PharMolix/UniProtQA huggingface dataset:
Protein: RL13_DICT6
Sequence: MKTFMAKKEEIKREWYVVDAKGKVLGRLASEIAKILRGKHKPIYTPHVDTGDFVIVVNAKDVVLTGKKEQQKIYFFHSGYPGGHRLISAKDMRAKSPEKMIYLAVKGMLPKGPLGRKMLKKLKVYAGPEHPHQAQKPKELNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CA171_CONPO
Sequence: MGMRMMFTMILLVVLVTTVVSFTLDRVLGPVSDGRNAAPDDEKFDRMEYFLSKCCANPSTCDLSLLCIFG
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Pl171.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARCH_HUMAN
Sequence: MAQEEEDVRDYNLTEEQKAIKAKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLQTVEVETQGDDLQSLLFHFLDEWLYKFSADEFFIPREVKVLSIDQRNFKLRSIGWGEEFSLSKHPQGTEVKAITYSAMQVYNEENPEVFVIIDI
What is the function of this protein?
Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB.  Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation.
What are the official names of this protein?
Protein archease, Protein ZBTB8OS, Zinc finger and BTB domain-containing opposite strand protein 8.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: PHNX_VIBC1
Sequence: MSNSPIQAVIFDWAGTIVDFGSFAPTSIFVEAFKQGFDFEIDLEEAREPMGLGKWDHIQAVGRIPAVDKRWNEKFGRSMTSEDIDAIYAAFMPLQKAKVADHADPILNAIEVVNGLKDKGIKIGSCSGYPREVMDVLIPVAADYGYKPDYVVATDDLPQGGRPAPFMALKNVIELNVTDVNACIKVDDAAPGIDEGHNAGMWTVGLLLSGNEAGLTFEEYQAADEATLNAAREKARAKLLKSSPHYLIDTIADFPEVVADIERRLAAGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: YQGF_LEVBA
Sequence: MKLMGLDVGSRTVGVAVSDALGWTAQGVEIIRINEDEEQFGLDRVGELIASHDVQGFVVGLPKNMNNSLGPRAEASKRYGDMLTARFNLPVDFEDERLTTVEAERMLVEQADTSRRKRKQVIDKLAAGLILQNYLDRHGKLTREK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAP3_LATCU
Sequence: NIPQLTPTP
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacteria L. monocytogenes, L. lactis subsp lactis and L. curvatus H28, but not against the Gram-positive bacteria L. curvatus CWBI-B28, L. brevis and L. plantarum or the Gram-negative bacteria E. coli and Pseudomonas sp 55.  Has no antifungal activity against S. cerevisiae, Penicillium sp BKS-TAN2 or A. niger.
What are the official names of this protein?
Bioactive peptide 3, BAP3.
What are the subcellular locations of this protein?
Secreted.
Protein: XYLT_LEVBR
Sequence: MRKVSTGFVYFFGALGGLLFGYDTGVISGAILFIQKQMNLGSWQQGWVVSAVLLGAILGAAIIGPSSDRFGRRKLLLLSAIIFFVGALGSAFSPEFWTLIISRIILGMAVGAASALIPTYLAELAPSDKRGTVSSLFQLMVMTGILLAYITNYSFSGFYTGWRWMLGFAAIPAALLFLGGLILPESPRFLVKSGHLDEARHVLDTMNKHDQVAVNKEINDIQESAKIVSGGWSELFGKMVRPSLIIGIGLAIFQQVMGCNTVLYYAPTIFTDVGFGVSAALLAHIGIGIFNVIVTAIAVAIMDKIDRKKIVNIGAVGMGISLFVMSIGMKFSGGSQTAAIISVIALTVYIAFFSATWGPVMWVMIGEVFPLNIRGLGNSFASVINWTANMIVSLTFPSLLDFFGTGSLFIGYGILCFASIWFVQKKVFETRNRSLEDIEATLRAKTGEDAAELSTTK
What is the function of this protein?
Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system).  Transport is driven by the proton motive force generated by either malolactic fermentation or by the metabolism of D-glucose.
What are the official names of this protein?
D-xylose transporter, D-xylose-proton symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUTB_ECO8A
Sequence: MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: PURQ_LYSSC
Sequence: MKFAVLVFPGSNCDIDMYHAIKDELGEEVEYVWHTATDLSGFDGVLVPGGFSYGDYLRCGAMANQSNIMAEVKKVADAGKPVLGVCNGFQILTEAGLLPGALLRNTNLKFMCRTVQLKVENNNTLFTNQYEQGQIIHIPIAHGEGNYYCDEETLQSLKDNNQIVFTYSGDNPNGSLEDIAGIINERGNVLGMMPHPERAVDALVGGADGLAVFKSIVKQWRENHVNN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DESI2_DANRE
Sequence: MANEPVILNVYDMYWINEFTSSLGIGVFHSGIEIYGREFAYGGHPYPFSGIFEITPGDATELGETFKFKEAIVLGSTDFTEEDVERIVEEMGKEYKGNAYHLMHKNCNHFSSALSEILCGREIPRWVNRLAYFSSCVPFLQSCLPKEWLTPAALQSSVSQELQGELEEAEDAAASASTPTCAVAPAPRPARHQPRR
What is the function of this protein?
Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
What are the official names of this protein?
Deubiquitinase DESI2, Desumoylating isopeptidase 2, DeSI-2, PPPDE peptidase domain-containing protein 1, Protein FAM152A.
What is the protein family that this protein belongs to?
Belongs to the DeSI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_HELP2
Sequence: MNTLGRFLRLTTFGESHGDVIGGVLDGMPSGIKIDYALLENEMKRRQGGRNVFITPRKEDDKVEITSGVFEDFSTGTPIGFLIHNQRARSKDYDNIKNLFRPSHADFTYFHKYGIRDFRGGGRSSARESAIRVAAGAFAKMLLREIGIVCESGIIKIGGIEAKNYDFNHALKSEIFALDKEQEEAQKTAIQNAIKNHDSIGGVALIRARSAKTNQKLPIGLGQGLYAKLDAKIAEAMMGFNGVKAVEIGKGVESSLLKGSEYNDLMNQKGFLSNRSGGVLGGMSNGEEIIVRVHFKPTPSIFQPQQTIDINGNECECLLKGRHDPCIAIRGSVVCESLLSLVLADMVLLNLTSKIEYLKTIYNEN
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GLMU_METFK
Sequence: MSLPTYSKLNIVILAAGKGTRMNSSKPKVLHALAGKPVLQHVLDTARRLNPSSIIVVYGFGGEIVPQALPADDIIWVKQAEQLGTGHAMQQALPYLEPDARTLILLGDVPLLTQESCTQLLTQQAALCLLTVSKDNPSGYGRIVRQGDAVKAIVEHKDAAEAQLAIREVNTGIMAAENTWLATWLPRLDNRNAQQEYYLTDIVAMAVADGQAVAAVQSNDEWQVAGINSKQDLAALERVYQGRYAARLLAKGVTLADPSRIDVRGELTTGRDVEIDVGCVFEGQVTLADNVRIGPYCVIRDATIGAGTTLAAYTHIDGATLAEDCRIGPYARLRPGTVLSDHAHIGNFVELKNAQVDSGSKINHLSYVGDATVGKQVNIGAGTITCNYDGVNKFRTVIEDNAFIGSDSQLVAPVTIKAGATIAAGSTITEDAPADKLTMSRVRQFTIENWKRPEKVKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BENC_ACIAD
Sequence: MSLYLNRIPAMSNHQVALQFEDGVTRFIRIAQGETLSDAAYRQQINIPMDCREGACGTCRAFCESGNYDMPEDNYIEDALTPEEAQQGYVLACQCRPTSDAVFQIQASSEVCKTKIHHFEGTLARVENLSDSTITFDIQLDDGQPDIHFLAGQYVNVTLPGTTETRSYSFSSQPGNRLTGFVVRNVPQGKMSEYLSVQAKAGDKMSFTGPFGSFYLRDVKRPVLMLAGGTGIAPFLSMLQVLEQKGSEHPVRLVFGVTQDCDLVALEQLDALQQKLPWFEYRTVVAHAESQHERKGYVTGHIEYDWLNGGEVDVYLCGPVPMVEAVRSWLDTQGIQPANFLFEKFSAN
What is the function of this protein?
Electron transfer component of benzoate 1,2-dioxygenase system.
What are the official names of this protein?
Benzoate 1,2-dioxygenase electron transfer component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: FOLD_RICTY
Sequence: MNNIIDGKALANEILADLKLEIQGFKEKTQTSPKLAIVLVGDNPASMIYIKNKIKNAQQVGIDTLLVNLSTNIYTDDLISKINELNLDKEISGIIVQLPLPSSIDENKILSAVLPSKDSDGFHPLNVGYLHSGINQGFIPCTALGCLAVIKKYAPNLNGKDAVIVGRSNIVGKPLSALLLKENCSVTICHSKTCNLSSITSKADIVVVAIGSPLKLTAEYFNPESIVIDVGINRISNNKIIGDVDFENVKSKVKYITPVPGGIGPMTIAFLLKNTVKAFKNAIAL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: YQA5_SCHPO
Sequence: MEIDLLSFSIKRILNLSAFIHIYSRYFRPDTFLSSKQSITMSVKKPYKHPNCTSVIHINRVAIVIEQEKGKKSKQNLIPS
What are the official names of this protein?
Uncharacterized protein C4F11.05.
Protein: SYN_STRT2
Sequence: MSKQLVSIIDVPKHIGEEITIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFIEKFGEEEGLEKFDTIKHLSQETSIYVTGMVKEDERSKFGYELDITDIEVIGKSQDYPITPKEHGTDFLMDNRHLWLRSRKQMAIQQIRNAIIYATYDFFDKNGFIKFDSPILSSNAAEDSTELFETDYFGTPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSFLSHDESLDLQEAYVKALIQGAIDRAPQALEILERDVDLLKKYIAEPFKRVSYDEAIDLLQAHENDEDTDYEHLEHGDDFGSPHETWISNYFGVPTFVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDDYDALVAKMEELGMDRSEYEFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIKP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BUCAT
Sequence: MKFIDQAIIHVIAGNGGNGCVSFRREKYIPKGGPDGGNGGDGGNIWLEANNNLNTLIDLRFKKKFQAQNGQNGSSRKSSGKKGDDIKIHVPIGTKVINYQTREIIGDLIQHKQKMLIAKGGWHGLGNARFKSSTNRTPRQSTLGSIGEKRDIQLELMLLADVGTLGMPNVGKSTLVTNISGAKTKISDYPFTTLHPVLGSVNIQKNKKFIIADIPGIIKGASYGAGLGIRFLKHLERCKLLLHIIDLVPQNNCHPSDNIKTVLNELKKYSLKLYNKPRWFIFNKIDLLSVEELNQIIKEIIFQFKIHEKYYLISSMKKIGIKKLCSDITKYLKK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_ROSS1
Sequence: MAQVMISQHPLVQHKLTLLRRATTEPKKFRELVRELSQFLLYEATLDLPLQERIVDTPLAPYHGHRIAERVGLVPILRAGLGMVDPILDLIPTAHVWHLGLYRDHATLKPVTYYNKLPPEVDVDLCLVLDPMLATGGSAVAAVTVLKEWGASRIKFLGLIAAPEGVQALHQEHPDVPIHLAAIDDCLNDHGYIVPGLGDAGDRLFGTG
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: REH1_YEAST
Sequence: MSSTFFTCNCCVIQFKTSDLQRYHMKTEWHRYNLKRRIANLPPIGAEQFAEKLQISEKEQAENQVDEFGFPVLKPVMNQSNALPQKQKKPIKSKRGRKVGTNLLKRKDRDIAKEKQNRSVSPSGSISSQLSNLTVGTENTNTDYGEDTVSEYGFTSDSNYEYATSDEELDIADKPSDKENEKITITECIYCGKDNKEVERNVKHMFSEHGLFIPERSYLIDLNGLLEFLIKMIVIDHNCLCCNFHGSGLESIRAHMASKRHCRLPYETKEERQLFAPFYDFTYDDHSISKNLQNDRAITSKLSSVYGAKNDEEDGEVDITLVSSENDINANYTTVSIDESGLELTLPTGARLGHRAGQRYYRQNLPSQPNPNESRRTITAADRRMVSGVTEKQYKKGMKKMQQLEKNAINTQIRREIKRVNFQTHYRDELLQ
What is the function of this protein?
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit.  May act redundantly with REI1 to directly promote a stabilizing structural rearrangement in cytoplasmic 60S subunit maturation independent on the REI1-specific ARX1 recycling.
What are the official names of this protein?
Cytoplasmic 60S subunit biogenesis factor REH1, REI1-homolog 1, pre-60S factor REH1.
What is the protein family that this protein belongs to?
Belongs to the REI1 family.
Protein: RL30_RHIWR
Sequence: MAGKTLKVTQIGSPIRRTADQRATLIGLGLNKMHRTRELQDTPEVRGMIRKVQHMVKVDEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PLSY_STRP7
Sequence: MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNTFRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKGGKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFGFILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLOA_STAAT
Sequence: MFSLSFIVIAVIIVVALLILFSFVPIGLWISALAAGVHVGIGTLVGMRLRRVSPRKVIAPLIKAHKAGLALTTNQLESHYLAGGNVDRVVDANIAAQRADIDLPFERAAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIARLVGGAGEETIIARVGEGIVSTIGSSKHHTEVLENPDNISKTVLSKGLDSGTAFEILSIDIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVATEQEMKARVQEMHAKVVEAESEVPLAMAEALRSGNISVKDYYNLKNIEADTGMRNAINKRTDQSDDESPEH
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.
Protein: COPA_STAA8
Sequence: MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLILTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTHYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
What is the function of this protein?
Involved in copper export.  Can also probably export ferric and lead ions.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase, Cu(I)-translocating P-type ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MEP50_HUMAN
Sequence: MRKETPPPLVPPAAREWNLPPNAPACMERQLEAARYRSDGALLLGASSLSGRCWAGSLWLFKDPCAAPNEGFCSAGVQTEAGVADLTWVGERGILVASDSGAVELWELDENETLIVSKFCKYEHDDIVSTVSVLSSGTQAVSGSKDICIKVWDLAQQVVLSSYRAHAAQVTCVAASPHKDSVFLSCSEDNRILLWDTRCPKPASQIGCSAPGYLPTSLAWHPQQSEVFVFGDENGTVSLVDTKSTSCVLSSAVHSQCVTGLVFSPHSVPFLASLSEDCSLAVLDSSLSELFRSQAHRDFVRDATWSPLNHSLLTTVGWDHQVVHHVVPTEPLPAPGPASVTE
What is the function of this protein?
Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones (PubMed:11756452).  This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.  Might play a role in transcription regulation.  The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage (PubMed:23071334).
What are the official names of this protein?
Methylosome protein 50, MEP-50, Androgen receptor cofactor p44, WD repeat-containing protein 77, p44/Mep50.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear in Leydig cells and cytoplasmic in germ cells during fetal testicular development. In adult testis, predominantly nuclear. Subcellular location varies from nuclear to cytoplasmic in various tumors (PubMed:17437848).
Protein: Y1158_ARCFU
Sequence: MVTMDRTEILEKIKQAEIKVEEAIRAAEEERKNKILEAKMKAREIIESAEAEAVKVKEDILNSARQQIEAEKEEIRKRETKNIEDYAKKGKDNIMKAVEMLYNEFVGMMEHA
What are the official names of this protein?
Uncharacterized protein AF_1158.
Protein: BGL32_ORYSJ
Sequence: MAAGARALVPSPFIVVVFLLLAAAARDASALTRHDFPEGFVFGAGTSAFQVEGAAAEDGRKPSIWDTFTHQGYSPGGAIADVSADQYHHYKEDVKLMYDMGLDAYRFSIAWPRLIPDGRGEINPKGLEYYNNLIDELIMHGIQPHVTIYHFDLPQALQDEYGGILSPRFIEDYTAYAEVCFKNFGDRVKHWVTVNEPNIEPIGGYDAGVQPPRRCSYPFGTNCTGGDSSTEPYIVAHHLLLAHASAVSIYRQKYQAIQGGQIGITLLGWWYEPYTDAVADAAAAIRMNEFHIGWFMNPLVHGDYPPVMRSRVGARLPSITASDSEKIRGSFDFIGINHYFVIFVQSSDANHDQKLRDYYVDAGVQENGGGGFDKEHYQLHPWALGKMLHHLKLKYGNPPVMIHENGDADSPETPGKIDYDDDFRSDFLQSYLEVLHLSIRNGSNTRGYFVWSLLDGFEFLSGYGNRFGLCCVDFTAPARTRYVRSSARWYSDFLNGGELRPVKPFVAL
What are the official names of this protein?
Beta-glucosidase 32, Os9bglu32.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: PGK_RHOBA
Sequence: MAKKTIDQIDVQDKTVLMRVDFNVPLDESLAITDDRRIRMALPSIKSVIDRGGKVILMSHLGRPTGGEGDEKYSLAPAAKRLGELLGSTVHFATDTVGDDASSKASSLAAGEVLVLENLRFNPGEKKGDSEFAGKLAAMADAYCNDAFGTCHRKDASMVAVPEAMAGKPRVVGHLVAKEIQYLTDAISKPERPFVAILGGAKVSDKINVINNLLGICDAVLIGGAMAYTFSLASGGKVGKSLVEKDKVELAKELMAKGGDKLQLPVDTHCGDDFGNIAGCNKKVVAAGEIPDDMEGLDIGPETAKKYAEVIKSAKTIVWNGPMGVFEKPPMDEGTKAVAQAIADGDAVSIIGGGDSAAAVDQLGFADDVSHVSTGGGASLAMLEGQAFAAVDLLDEA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAS_CARAU
Sequence: MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLPSRSVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLRKLSKEEETTQCIKL
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
Ras-like protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: NTPPA_PARXL
Sequence: MSTSAASLHPFVYLASQSPRRQELLQQLGVRFELLLPRPDEDAEALEAELPGERAHAYVQRVCVAKAHAARARLVAGGHAARPILVADTTVTIDDAILGKPVDADDAFAMLTRLAGRDHEVLTAVAVVDAEGTLLPAALSVSKVRFAALHAEAIRRYVASGEPLGKAGAYGVQGRAAEFIGHIDGSYSGIMGLPLFESAALLRAARIDF
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_CHLTB
Sequence: MSHLFSKACQYFPGGVNSPVRACRAVNITPPIVARASKEVFIDSLDKTFIDFCGSWGSLIHGHSHPKICAAIRQGLERGSSYGLTSEQEILFAEEIFSYLGLETNYKIRFMSTGSEATMTAVRLARGITGRPIIIKFLGCYHGHADTFLQEKPFSHTSLDTLDLAHPLTLSLPFNDFPLFQTVMNSLGHKVAGVIFEPVCANMGVILPVPDFIEGVIQTCQQTGSFSIMDEVVTGFRVAQGGAAALYHVKPDILVFGKILGGGLPASAVVAPKDIMDHLAPEGKIFQAGTLSGNPLAMIAGKVSVNLCREQGFYTQLATIEQNFLSPIEHMIRTTGIPVTLVRYGSLFSFFFNPNRPNNLADAQLSDIEAFQKFYQSAFSKGVYLSPSPFEASFLSAAHSMESLDYAQTALIESLEQVFSLV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_SYNP6
Sequence: MSVRVRIAPSPTGNLHIGTARTAVFNWLFARRHQGQFILRIEDTDLERSRSEYTDNILTGLQWLGLNWDEGPFYQTQRLDLYKAAVQQLLDSGKAYRCYCTEAELEALRESQRARNEAPRYDNRHRDLTPEQEAAFQAEGREAVIRFRIDDDREIAWTDLVRDRVVWKGSDLGGDMVIARRSPAGTIGQPLYNLAVVVDDIDMTISHVIRGEDHIANTAKQILLYEALGAAVPEFAHTPLILNKEGRKLSKRDGVTSISDFQNLGYLPEAIANYMTLLGWSPVEGMDERFSLAEAATVFDFDRVNKAGAKFDWDKLNWLNSQVIKEKSASELVALLQPFWSKAGVDTAAYPAAWLEELATLLGPSLVTLTDIVGQSQLFFSQGIELQEDAIAQLGQAGSKAVLQQILEALPSEALTLEVAKGLIDQAVKAAGVKKGIGMRSLRAALMGSMQGPDLLTSWVLLHQAGQAQPRLQAAIAAAQG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.