PharMolix/UniProtQA huggingface dataset:
Protein: Y1643_ARCFU
Sequence: MGIKTQKNFICLKRTFSMNLRDAISVANPVQLEEEIKHDEVVSFLKSKNLLDKPVILNVEGKKVAKNFVSSRETLGKYLGVDAYSIARELSKIEDREAEIRVEPFSSLAMKKVDVNLQELPVIKYFPRDGGRYITAGIVIAQRNGVYNASIHRMLLLDESRVAARLVPPRHTYLMWREAVEREEELEVAVVIGTHPLFLFASATRVPSGKEFSYAAGLMGRLTLYRKGEMLVPDSEIILFGRITAETAKEGPFVDITGTYDIVRDEPVIVFDEMYVKEDYIYYSITPAGKEHQMLMGVPYEPVIYRFVSNVCKVKNVITTPGSCHYFHCVVQIEKKSEGDGKNAIIAALAANPSMKGVVVVDDDIDILSYEDMEFAIATRFQPDRDLVVVKGARGSSLDPSADKTTSKWGIDATKPLGKEGFDRVV
What are the official names of this protein?
Uncharacterized protein AF_1643.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
Protein: RL2_NEIMA
Sequence: MAIVKMKPTSAGRRGMVRVVTEGLHKGAPYAPLLEKKNSTAGRNNNGHITTRHKGGGHKHHYRVVDFKRNKDGIPAKVERIEYDPNRTAFIALLCYADGERRYIIAPRGIQAGAVLVSGAEAAIKVGNTLPIRNIPVGTTIHCIEMKPGKGAQIARSAGASAVLLAKEGAYAQVRLRSGEVRKINVNCRATIGEVGNEEQSLKKIGKAGANRWRGIRPTVRGVVMNPVDHPHGGGEGRTGEAREPVSPWGTPAKGYRTRNNKRTDNMIVRRRYSNKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ISCS_SHESA
Sequence: MKLPIYLDYAATTPVDPRVAEKMFQYMTMDGIFGNPASRSHRYGWQAEEAVDVARSQVADLINADHREIVFTSGATESNNLAIKGVAHFYNKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLEPEANGIIPMERLEAAMRDDTILVSIMHVNNEIGVIHDVDAIGELCRSKGIIFHMDAAQSAGKLPIDVQTTKVDLISISGHKMYGPKGIGALYVRRKPRIRLEAQMHGGGHERGMRSGTLATHQIVGLGEAAAIAKAEMATDNARIAKLRDKLWNGIKHIEETYVNGDMTHRVSGSLNVSFNYVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTEEEIDHAIETITQSIDKLREMSPLWEMFKDGIDLNQVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMI_SALDC
Sequence: MTESTFPQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLGETIDIVDHQGKWLARGAWSPASQIRARVWTFDKAESIDIAFFTRRLRQAQQWRDWLAKKDGLDSYRLIAGESDGLPGVTIDRFGHFLVLQLLSAGAEYQRAALISALQTCYPDCAIYDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEHGMKLLVDIQGGHKTGYYLDQRDSRLATRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLDLSKAEFVRDDVFKLLRAYREHGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQLLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CHLL3
Sequence: MPKMKSHRGACKRFKATASGKIKRERMNGSHNLEKKNRKRTRRLHQSTMLDNATKEKQIKRMILA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ARSC_OCEIH
Sequence: MSKKIIYFLCTGNSCRSQMAEGWGKKILGEEWDVYSAGIEAHGLNPNAIKAMREVDIDITNQTSDQIDKDILNKADFVVTLCGDAKDKCPMTPPHVKRDHWGFEDPAKAQGTEEEKWTVFQQVRDKIGDRIKVFAKTGE
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_MALP2
Sequence: MIEYIIGKISYKNNNYLILENNFKGYKLFMSDPNIFEENSSAKIFVYTKIFQNNKNNFLFEYYGFKTLREKIFFENLLTVNGIGPKTSLTILRNDLNLLKELIRNEDIESLSVLEGFTNKTALSIVSALSYKLKNERISEYNNDVNHSSINQQSNSYNPVPDLVSALKALGYKKNMIEKAINLLIPQLSNVSEDQISDLISQAIKIISDEAVTNKTTVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NPR3_CANAL
Sequence: MSLNLPNPSLIGILLVISTHSGPQLIYKYPFDLSNDPSRDESKYALDDNEDDELYDHEESEDENEVNENEMYGVNSRNWDSKHIDYYMGTKSDLLKFLDEQDSRRRKITTTSPSEEKHTKEKHGLTKTISKSSTMASSSTTSPPESSIQGEIFGTDAAYICEMLAPPKQMCNTRFEMTIQDKLFLGLPVHRSDNGQWRSIGHNNEHDEEETHTAKNSLNMFHLVFVMNPPVIESNYRVDEMFHYVISRLSLVLRYEQQKHDYVSQQVKNILALRESLEGNESLLTEKSSLSRVIRDCFEGISTSTIANLSINGKLRSFQIPIKTEFHSLPDPSVPFLPASYLSSTVELLGDTSFINVGETSRYGHAFNSVQDEENSAEKIIVYFALLLLDDPESIIKDMKTETDSTLAKFIRMIEPTESLLKLSARNSKLDISQIKDFAFHLIYWRRARVILPLSSRSVYIVSPMAPITIKLYDDISFFNRRFPTLPSLPHFLKLLSPQSRKPQQFATVIPSKDHRDRYLQALGWLIKHGYVTQLQTFIWLKISRKIKIKVEEDIENENLAKKKKKQKNGSVTVATANSSKTEAPIMPTDNTSKQVSDSKDSDKPEDDEYASKPRLDGLHEHIDGTPIVTLVQGDDTIILDPGRATTLERRWINKIIYEECKLSPELTAVFYKLLKYMNGKNSLELLLLKENISRSELRKLLLSIEEHIISVRHW
What is the function of this protein?
Mediates inactivation of the TORC1 complex in response to amino acid starvation.  Required for meiotic nuclear division (By similarity).
What are the official names of this protein?
Nitrogen permease regulator 3, Required for meiotic nuclear division protein 11.
What is the protein family that this protein belongs to?
Belongs to the NPR3 family.
Protein: ENGB_CALS4
Sequence: MKIKTAEFVGSAFNESQYPKDKIPQIAIVGKSNVGKSTLINTVLGRKNLAKVSSTPGKTRGINFYLVNRAFYIVDLPGYGYAKVSKEMKKQWAYNIETFLNTSKNLKHALLLIDIRREPTEDDFMMVNWFSFKNLPFSVVLTKADKVNKSEANKAIENICRSFNISSDRVIVFSAVEKTGISEILRIFEEVIEK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: LSM2_ARATH
Sequence: MLFFSYFKDLVGQEVTVELKNDLAIRGTLHSVDQYLNIKLENTRVVDQDKYPHMLSVRNCFIRGSVVRYVQLPKDGVDVDLLHDAARREARGG
What is the function of this protein?
Component of LSM protein complexes, which are involved in RNA processing.  Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by promoting decapping and leading to accurate 5'-3' mRNA decay.  The cytoplasmic LSM1-LSM7 complex regulates developmental gene expression by the decapping of specific development-related transcripts.  Component of the nuclear LSM2-LSM8 complex which is involved splicing nuclear mRNAs.  LSM2-LSM8 binds directly to the U6 small nuclear RNAs (snRNAs) and is essential for accurate splicing of selected development-related mRNAs through the stabilization of the spliceosomal U6 snRNA.  Plays a critical role in the regulation of development-related gene expression.
What are the official names of this protein?
Sm-like protein LSM2, AtLSM2, U6 snRNA-associated Sm-like protein LSM2.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THIC_PROM1
Sequence: MRNSWVASRKGKTNVSQMHFARKGEITEEMRYVAKRENLPESLVMEEVARGRMIIPANINHINLEPMAIGIASTCKVNANIGASPNASDISEELKKLDLAVKYGADTLMDLSTGGVNLDEVRTEIINASPIPIGTVPVYQALESVHGSISRLNEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRITGIVSRGGGILAQWMLYHYKQNPLFTRFDDICEIFKRYDCTFSLGDSLRPGCLHDASDEAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPMDQIEFNVRKQMEECSEAPFYVLGPLVTDISPGYDHISSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADVARHRSGARDRDDELSKARKEFDWNKQFELSLDPEKAKQYHDETLPEEIFKKAEFCSMCGPNHCPMNTKITDEDLDQLNDQIQSKGAAELTPVKLNKEN
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: TSAD_SHELP
Sequence: MRVLGIETSCDETGIAVYDDEKGLLSHALYSQVKLHADYGGVVPELASRDHVRKIIPLIRQALKEANCTQDDIDAIAYTKGPGLVGALLVGACVGRSLAFAWGKPAVGVHHMEGHLLAPMLEEDVPEFPFLALLVSGGHSMMVAVEGIGRYQVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLAKLAAQGEPNCYRFPRPMTDRPGLDFSFSGLKTFAANTIADEPDDEQTRANIARAFEEAVVDTLAIKCKRALKQTGYNRLVIAGGVSANSRLRESLAEMMQGLGGRVYYPRGEFCTDNGAMIAYAGMQRLKADQLEPLAVKGMPRWPLDSLPPV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_LARHH
Sequence: MQSRKLYKSLYFQVIVAIICGVLLGHFMPDSGTAMKPLGDGFIKLVKMMITPIIFCTVVVGIAGMEDMKKVGRVGGKALLYFEVVTTLALIIGLVVVNVLKPGAGMNVDPATLDTGAIAKYTAKAGEQSVVDFVLHIIPNSVVGAFAEGEILQVLLFSVLFGFALSMMGQSGKPVVKLVEDISHALFAAIGFIMKLAPIGAFGAMAFTIGKYGVSSLSSLAALMGSFYLTCLLFIGLVLGTITRFCGFSIWKLVRYIKEELLIVLGTSSSESALPRLMAKLEQLGCQKSVVGLVVPTGYSFNLDGTSIYLTMAAIFIAQACGIELTLTQELTIIGVLLLTSKGAAGVTGSGFITLAATLATVPDIPVAGLALILGIDRFMSEARALTNLVGNTVATVVVAKWENALDSDKLAAELHNPTPLAHGLKVEAPHLTREVSRTLS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CP17A_PAPCY
Sequence: MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQVTTLDILSNNRKGIAFADYGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQTIDISFPVFVAITNVISLICFNISYKNGDPELKIVHNYNEGIIDSLGKESLVDLFPWLKVFPNKTLEKLKRHVKTRNDLLTKIFENYKEKFRSDSITNMLDVLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWIVAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRIRPVAPMLIPHKANVDSSIGEFAVDKGTHVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSLSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGNPKVVFLIDSFKVKIKVRQAWREAQAEGST
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.
Protein: RLME_AERHH
Sequence: MTQKKHSPSSTRWLKEHFDDQYVKKAQKLGLRSRAVFKIDEIQGKDKLLKPGMTVVDLGAAPGGWSQFAIDQVGDKGRVIACDILPMDSIAGVDFLQGDFREETVLGALLERVGPDKVDVVMSDMAPNMSGTQQVDQARSMYLVELALDMCNQVLRANGSFVVKVFQGEGFDIYLNEIRKLFTAVKIRKPDSSRARSREVYIVATGFKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_ECOL6
Sequence: MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIGAFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVFVNLLGSFAMTALAFWLFSASTAH
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURA_PLAKH
Sequence: MNIFEHDIQNLSQGNVVAILGSQWGDEGKGKIIDILSKHSDITCRFNGGANAGHTISVNDKKYALHLLPCGILYENNICVLGNGMVVHLKSLINEINSIGGNIIERLYLSDKSHILFDIHQTIDSIQENRKLKEGKQIGTTKRGIGPCYSTKVSRVGIRLGSLKNFEHFKNLYLKLIDNLMELYDIKDYNKEEELESFYKYHLLLKDRIIDVISFMNNRLNEKKNILIEGANAAMLDIDFGTYPYVTSSCTTVGGIFSGLGINHKKLNLTIGVVKSYLTRVGCGPFMTELNNEIGAYLREKGHEYGTTTKRPRRCGWLDIPMLLYVKCINSIDIINLTKLDVLSGLKEILLCVGYRSKGTGELLQKGCYPVDEDAPENYEPVYEQFQGWEEDISNCQTFEELPENAQKYVLAIEKYVDSPIVWIGVGPNRNNTITKK
What is the function of this protein?
Plays an important role in the salvage pathway for purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_AGRRK
Sequence: MPKMKTKSSAKKRFKITATGKVKAAAAGKRHGMIKRSNKFIRDARGTMVLAEPDGRKVIKNYLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: VP10_NPVSE
Sequence: MSQNILLLIRADIKAVDEKVDALQQAVNDVSANLPDTSELSAKLDAQATTLDTIVTQVNNINDVLNPDLPDVPGNLQKQQQQKKSNKK
What is the function of this protein?
Seems to be involved in the morphogenesis of the polyhedra.  Forms extensive fibrillar structures in both nucleus and cytoplasm.  It is involved in the liberation of polyhedra from infected-insect cell.
What are the official names of this protein?
Protein p10, Fibrous body protein.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae p10 family.
Protein: DHR11_HUMAN
Sequence: MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMRPTEQVT
What is the function of this protein?
Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites.  Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids.  May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 11, 17-beta-hydroxysteroid dehydrogenase, 3-beta-hydroxysteroid 3-dehydrogenase, Estradiol 17-beta-dehydrogenase, Short-chain dehydrogenase/reductase family 24C member 1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1205_BACC4
Sequence: MVHMHITAWALGLILFFVAYSLYSAGRKGKGVHMGLRLMYIIIIVTGFMLYMSIVKTATGSMHMWYGLKMLAGILVIGGMEMVLVKMSKNKPTGAVWGLFIVALVAVFYLGLKLPIGWKVF
What are the official names of this protein?
UPF0344 protein BCB4264_A1205.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EAF3_CRYNJ
Sequence: MAGAVPQFMVDEYVLAYHGPLLYEARVILAEVWDESNTLLGTVGPHYFIHYKGWKQTWDEWVPESRLLKLNEAGFAKRRALLDAQAKKGRSTGGSGGTGSPGAGKGGLKDKKKDTKKRGRDAMESESDFMKRPEVKIVIPDVLKLVLVDDWENVTKNNQLVALPRKPNVRELLEEYRQYASASKKQERSDRATALLSEIISGITLYFDKALGNNLLYRFERAQYVEQKRQNPEKPMSEIYGAEHLLRLFVNFGPFIAYTNIDTESLNILRDYINDIMQWMIKEQKRLFMKEYEETTTHYQNLSRS
What is the function of this protein?
Involved in deacetylation of histones, chromatin assembly and chromosome segregation.  May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF3.
What is the protein family that this protein belongs to?
Belongs to the MRG family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NHAA2_PSEA6
Sequence: MQSYLGKLIQHEAAGGVLLVIAAAIAMVLANSPAYDFYNGLLEIPVSIRFGAFEIAKPLLLWVNDGLMAIFFFLVGLEVKREVLGGQLSSVSQITLPAVAAIAGIVFPALIYVWFNIDDPVAVNGWAIPSATDIAFAVGVFTIFGKFLPLSLKLFLLSVAIFDDIGAIVIIALFYSQDLSTTSLIVACAGFVALFLLNRFNVRRQAAYVLIGVVVWAAVLKSGVHATLAGFALAWFIPLKLKNEDGHPMLPHLEHKLHPWVGFVVLPIFAFANAGVSLFGASISDLLNPITLGIAVGLFVGKQLGIFGVCWITVKTGLAKLPDGSTWVQLYGVSLLCGIGFTMSLFIGSLAFEEQGLAYQTSVKAGVLLGSLVSAVLGAVLLARSNAKSKERAEREAARDA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OTX5_XENTR
Sequence: MMSYIKQPHYAVNGLTLAGTGMDLLHSAVGYPTTPRKQRRERTTFTRAQLDILEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQQSTGQAKPRPAKKKTSPARETNSEASTNGQYSPPPPGTAVTPSSTASATVSIWSPASISPIPDPLSAATTPCMQRSAGYPMTYSQAPAYTQSYGGSSSYFTGLDCGSYLSPMHPQLSAPGATLSPIATPTMGSHLSQSPASLSAQGYGASSLGFTSVDCLDYKDQTASWKLNFNATDCLDYKDQSSWKFQVL
What is the function of this protein?
Transcription factor involved in anterior and eye development.  Promotes the differentiation of both rod and cone photoreceptors cells in the retina.  Together with other retinal homeobox proteins, acts as an effector of a cellular clock which, depending on cell cycle progression, establishes the generation of distinct retinal neuronal cell types.  Acts synergistically with nrl to activate the rhodopsin promoter.  Promotes the formation of anterior regions and represses the formation of posterior structures during development (By similarity).
What are the official names of this protein?
Homeobox protein otx5, Orthodenticle homolog 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: PANC_NITOC
Sequence: MRVLRTVAAVRSAVEGWRASHERVALVPTMGNLHRGHLALVERAAQLADRVIVSIFVNPLQFNDRDDYSRYPRTFEKDQQYLDEYGVAVVFAPSLEDIYPQRLENVTHVEVPGLSDILEGASRLGHFRGVTTVVAVLFNIIQPQVAVFGEKDYQQLLIIRRMVADLLMPVEVESIATVRDKDGLALSSRNSYLTKEERARAPILFGALSHAAETIKEGWRNFSILEEEGRQRLVTAGFCPDYFHIRRAEDLAEPGGRENNLVVLAAAYLGKARLIDNMQVQLKSVD
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG057_VACCP
Sequence: MWPFASVPAGAKCRLVETLPENMDFRSDHLTTFECFNEIITLAKKYIYIASFCCNPLSTTRGALIFDKLKEASEKGIKIIVLLDERGKRNLGELQSHCPDINFITVNIDKKNNVGLLLGCFWVSDDERCYVGNASFTGGSIHTIKTLGVYSDYPPLATDLRRRFDTFKAFDSAKNSWLNLCSAACCLPVSTAYHIKNPIGGVFFTDSPEHLLGYSRDLDTDVVIDKLKSAKTSIDIEHLAIVPTTRVDGNSYYWPDIYNSIIEAAINRGVKIRLLVGNWDKNDVYSMATARSLDALCVQNDLSVKVFTIQNNTKLLIVDDEYVHITSANFDGTHYQNHGFVSFNSIDKQLVSEAKKIFERDWVSSHSKSLKI
What is the function of this protein?
Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell.  Produces the wrapped form of virus that is required for cell-to-cell spread.  Acts as a lipase with broad specificity including phospholipase C, phospholipase A, and triacylglycerol lipase activities.
What are the official names of this protein?
Envelope phospholipase OPG057, 37 kDa protein, Envelope phospholipase F13, Envelope protein F13, Palmitoylated EV membrane protein, p37K.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG057 family.