PharMolix/UniProtQA huggingface dataset:
Protein: IMDH2_XENTR
Sequence: MADYLISGGTSYVPDDGLTAQQLFGAGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPMVSSPMDTVTEASMAIAMALTGGIGIMHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKHRVRDVFEAKARHGFCGIPITENGKMGSKLAGIISSRDIDFLKSEEHDLALSEIMTRREDLVVAPAGVTLKEANEILQRSKKGKLLPIVNGNDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLVQAGVDAVVLDSSQGNSIFQINMIKFIKEKYQDLQVIAGNVVTAAQAKNLIDAGADALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQTVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKNVSSQKRYFSEADKIKVAQGVSGAVQDKGSIHKFIPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTMSAQVEGGVHGLHSYEKRLF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase 2, IMP dehydrogenase 2, IMPD 2, IMPDH 2.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytosol. Note=Can form fiber-like subcellular structures termed 'cytoophidia' in response to intracellular guanine- nucleotide depletion.
Protein: APAH_ECO27
Sequence: MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYNIAFGHWASLEGKGTPEGIYALDTGCCWGGTLTCLRWEDKQYFVQPSNRHKDMGEGEAVAS
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: ODP1_ECOLI
Sequence: MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQEQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTIKGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFNIDADKVNPRLA
What is the function of this protein?
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component, PDH E1 component.
Protein: Y126_TREPA
Sequence: MRTHDIPRSPLVGHKKNAAPDGIGASRACCPARENEPFKKGSTNSRGGGVEWSRSSTRRVRGSALERGMKQLKWWAVGPVLGICAGVWGAAHPVHADPWDTTAAGRSTIRLSAMGAVPLFQVDWCNSGRGDDRNANAQTNGHKYIYPAFSAALGFEHFVCRGLSLGIDASVQYHCSYPNNTYSPTTPYYYLAIPVALTAGYTVAFWRIRLPLTVGAGFNYQHYYTSTYYGLVLKAAAGCYFQLTEHWSLGVSATYSGVPRSCEKIIEEDRQQTNTRTAQFIAAGVDVRYHL
What are the official names of this protein?
Uncharacterized protein TP_0126.
What is the protein family that this protein belongs to?
To T.pallidum TP_0733.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CF107_HUMAN
Sequence: MFLTAVNPQPLSTPSWQIETKYSTKVLTGNWMEERRKFTRDTDKTPQSIYRKEYIPFPDHRPDQISRWYGKRKVEGLPYKHLITHHQEPPHRYLISTYDDHYNRHGYNPGLPPLRTWNGQKLLWLPEKSDFPLLAPPTNYGLYEQLKQRQLTPKAGLKQSTYTSSYPRPPLCAMSWREHAVPVPPHRLHPLPHF
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Cilia- and flagella-associated protein 107.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: SYT_BRUAB
Sequence: MSNTVSLQFPDGSVREYDASMTGAALAESISKSLAKKAVAYAVDGTVRDLSDPLGASGKLEIITREDPRALELIRHDTAHVLAEAVQELFPGTQVTIGPVIENGFYYDFARNEPFTLDDLPVIEKKMREIIQRNKPFTKEVWSREKAKQVFSDKGESYKVELVDAIPAGQDLKIYYQGDWFDLCRGPHMASTGQIGNSFKLMKVAGAYWRGDANNPMLTRIYGTAFANDNDLQAYLHMLEEAEKRDHRRLGREMDLFHFQEEGPGVVFWHAKGWKMFQNLVSYMRRRLDSHGYQEVNTPQVLDKSLWETSGHWGWYRDNMFKVTVAGDDTDDDRVFALKPMNCPGHVQIFKHGLKSYRDLPIKLAEFGNVHRYEPSGALHGLMRVRGFTQDDAHIFCTEEQMAAECLHINDLILSVYKDFGFEEITIKLSTRPEKRVGSDELWDRAESVMMTVLEQIRQQSNNIKTGILPGEGAFYGPKFEYTLKDAIGREWQCGTTQVDFNLPERFGAFYIGADSEKKQPVMIHRAICGSMERFLGILIENFAGHMPLWFAPVQVVVATITSDADEYAKEAAAKLKAAGLQVVTDLRNEKINYKVREHSLQKVPVILVCGKREAEEKTVNMRRLGSRDQESMTLDEAIARLCEEATPPDLLRLKNAG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK12_TUPAK
Sequence: MTTVEQIIDQLKTLTLIESSELVKQIEETFGVDASAPVGGAIMMAPGQESAGQEVVEEKTTFDVIVKDIASDKRVSVLKVIRKLTSLGLAEAKEFTVSLPKALKEGISKEEAAEAKKDLELAGAVVDIV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS13_AGABI
Sequence: MGRMHAPGKGISSSALPYRRTPPSWLKTTSEEVVEQIVKLARKGLTPSQIGVTLRNSHGIPQVRFVTGNKILRILKSQGLGPSIPEDLWHLIKKAVAVRKHMETNRKDKDSKFRLILIESRIHRLARYYKTKQQIPPTFKYDSATASTLIA
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PLY19_ARATH
Sequence: MEMVRLSKLMFTFCIAVLIPTIRGNISELDEYWSQRADEAREFTLQAYHSDPYEIVDHFHERHYDNSTDVTTPEEDGDAKPEEEEKEFIEMLGSSTNSTRRSLRGKGKGKWSKLKGPCTASNPIDKCWRCRSDWAKRRKKLTRCVRGFGHRTTGGKRGRIYVVTSNLDEDMVNPKPGTLRHAVIQKEPLWIIFKNDMSIRLNQELLINSHKTIDARGANVHVAHGAGITMQFVKNVIIHGLHIHHISESSGGMIRDSVDHFGMRTRADGDGLSIYGSSNIWLDHISMSKCQDGLIDAIVGSTGITISNSHFTHHNDVMLLGAQNTNEADKHMQVTVAYNHFGKGLVQRMPRIRWGFVHVVNNDYTHWELYAIGGSQGPTILSHGNRFIAPPHKPHYREVTKRDYASEDEWKHWNWRSDKDVFMNGAYFRQSGNPQYKCAHTRQQMIKPKNGLAVSKLTKYAGALDCRVGRRC
What are the official names of this protein?
Probable pectate lyase 19.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
Protein: P3_MOUSE
Sequence: MVVKKSRGSSQQLPGLGGQGGCTGFVGMLGTALLFISLPWGAQVMASANISTALGHTSGHYLSIGDGSVTEFDFPEKSEGIIVISSQYTGQTNGTGPSPILKVISLDTEVLTIKNVSAITWSSGGGFVVGIHSGLAGLAPLHLQLMDFYEAPPLLIEERRDFCIRVSPAEDLPSALNTNLGHFSENPILYLLLPLIFVNKCSFGCKVELEVLKELLQSPQPMLLGLLGQFLVMPFYAFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFISTVAATGFLPLSSAIYSYLLSIHETLHVPISKILGTLLFIAIPIAAGVVIKSKLPKFSELLLQVIKPFSFILLLGGLFLAYHMGVFILVGVRLPIVLVGFTVPLVGLLVGYSLAICLKLPVAQRRTVSIEVGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGQFIYSILFPVP
What is the function of this protein?
The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions.
What are the official names of this protein?
P3 protein, Solute carrier family 10 member 3.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DALD3_HUMAN
Sequence: MATRRLGVGETLGALNAALGPGGPVWIKETRTRHLRSRDFLAPHRALQARFDDGQVPEHLLHALACLQGPGVAPVLRCAPTPAGLSLQLQRSAVFERVLSAVAAYATPASPASLGQRVLLHCPALRSSPCALRLSQLRTVLVADHLARALRAHGVCVRLVPAVRDPHMLTFLQQLRVDWPAASERASSHTLRSHALEELTSANDGRTLSPGILGRLCLKELVEEQGRTAGYDPNLDNCLVTEDLLSVLAELQEALWHWPEDSHPGLAGASDTGTGGCLVVHVVSCEEEFQQQKLDLLWQKLVDKAPLRQKHLICGPVKVAGAPGTLMTAPEYYEFRHTQVCKASALKHGGDLAQDPAWTEIFGVLSVATIKFEMLSTAPQSQLFLALADSSISTKGTKSGTFVMYNCARLATLFESYKCSMEQGLYPTFPPVSSLDFSLLHDEGEWLLLFNSILPFPDLLSRTAVLDCTAPGLHIAVRTEMICKFLVQLSMDFSSYYNRVHILGEPRPHLFGQMFVRLQLLRAVREVLHTGLAMLGLPPLSHI
What is the function of this protein?
Involved in tRNA methylation.  Facilitates the recognition and targeting of tRNA(Arg)(CCU) and tRNA(Arg)(UCU) substrates for N(3)-methylcytidine modification by METTL2A and METTL2B.
What are the official names of this protein?
DALR anticodon-binding domain-containing protein 3.
Protein: PHNW_PSEP1
Sequence: MSNAPILLTPGPLTTSIRTRQAMLVDWGSWDRDFNQLTASVCEQLLAIIDGASSHHCVPLQGSGTFAVEAAIGTLVPRDGKVLVLINGAYGQRLAKICKVLGRTYSTFETAEDQPTTAADVDRLLAEDSAITHVALIHCETSTGILNPLPEIAQVIKHHGKRLIIDAMSSFGALPIDAREIPFEALIAASGKCLEGVPGMGFVFAEKNALAAAEGNAHSLAMDLHDQHAYMAKTGQWRFTPPTHVVAALHEALQQYNEEGGLPARHQRYADNCKTLLDGMAAIGLRSFLPAEIQAPIIVTFHAPTDARYQFKDFYERVKAKGFILYPGKLTQVETFRVGCIGVVGADGMQAAVNAVAEVLREMEVLDI
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: ARLY_CARHZ
Sequence: MKLWGGRFEKDTDREMRDFHASIHFDWRLYEEDIRGSIAHVTMLARQGIITNEEKEKIIGALTEILEEIKAGKVDFSPEAEDIHLNIETLLIKKIGDVGKKVHTGRSRNDQVALDTRLYVKKEGTAIIALIKELQETLINLAEGHLNTIMPGYTHLQRAQPVTLAHHLLAYFWMFDRDRSRFYDCLKRADRSPLGAGALAGTTLPLDREFVSELLGFNGVCENSLDAVSDRDYILEFLFAAATTMMHLSRFSEEIVLWNSKEFSFVEIDDRYATGSSMMPQKKNPDAAELIRGKTGRVYGNLMAVLTMMKGLPLAYNKDMQEDKEPLFDTVDTLKGSLRVFTGMLKTIKFNQGAMYKAALKGFLNATDLAEYLVEKGVPFREAHRITGELVLKAEKTGRELLELSLDELKEMSPLIEEDIYEKLKIENVLAKRKLFGGPAPQAVIEQLRQAREALA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR2_DRANE
Sequence: MTKRYWNIDLEEMMRAGVHFGHGTRKWNPRMAPYISAKRKGIHIINLTRTARFLSEACDLVFDAASRGKQFLIVGTKNKAADLVSRAAIRARCHYVNKKWLGGMLTNWSTTEKRLHKFRDLRTEQKTEGFNRLPKRDAAVLKRQLSRLETYLGGIKYMTGLPDIVIIIDQQEEYTALRECITLGIPTISLIDTNCNPDLADISIPANDDAIASIRFILNKLVFAICEGRSSYIQNY
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PNP_XANC5
Sequence: MAKITKTFQYGKHTVTLETGEIARQAGGAVIVKFDDTVLLVTAVAAKSAREGQDFFPLTVDYQEKFYAGGRIPGGFFKREGRATEKETLISRLIDRPIRPLFPEDYKNEVQIIATVMSMNPDIDGDIAALIGASAALSLAGTPFKGPIGAAKVGYKNGEYILNPTVTELKDSQLELVVAGTANAVLMVESEAELLSEEVMLGAVTFGHREMQKVINVINELTVEAGTKPSDWVAPAKNEGMIAALKEAVGDQLASAFQVRDKLQRRDAISAIKKDVLGALAPRATIEGWAAGDLAKEFGELEYQTMRGSVLSSKVRIDGRALDTVRPISAKAGVLPRTHGSALFTRGETQAIVITTLGTARDGQVIDAVSGEYKENFLFHYNFPPYSVGECGRFGAPKRREIGHGRLAKRGVLAVMPTLEEFPYTIRVVSEITESNGSSSMASVCGSSLALMDAGVPIKAPVAGIAMGLVKEGNDFVVLSDILGDEDHLGDMDFKVAGTAEGVSALQMDIKIEGITEEIMKQALQQAKAGRLHILGEMAHALTTPRQELSDYAPRLLTIKIHPDKIREVIGKGGSTIQAITKETGTQIDIQDDGTIIIASVNAIAAQAAKSRIEQITSDVEPGRIYEGKVAKIMDFGAFVTILPGKDGLVHVSQISSERVEKVGDKLKEGDLVRVKVLEVDKQGRIRLSIKAVEEGEGVQASAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGSP1_LEPFX
Sequence: GLWDDLKAAAKKVVSSLASAAIEKL
What is the function of this protein?
Stimulates aggressive behavior in male frogs.  No effect on female frogs.
What are the official names of this protein?
Aggression-stimulating peptide, LASP.
What are the subcellular locations of this protein?
Secreted.
Protein: YL366_YEAST
Sequence: MIRYSSRNRSAREVPVRRHPIFQVQHWKTSNEHSYHYSLCITFRSNPRTLTFSKITVKNDGRNFSQKFFFSFLLKSFLRWINCSLPFEIWRRSKSISTHLR
What are the official names of this protein?
Putative uncharacterized protein YLR366W.
Protein: CAT_CLODI
Sequence: MVFEKIDKNSWNRKEYFDHYFASVPCTYSMTVKVDITQIKEKGMKLYPAMLYYIAMIVNRHSEFRTAINQDGELGIYDEMIPSYTIFHNDTETFSSLWTECKSDFKSFLADYESDTQRYGNNHRMEGKPNAPENIFNVSMIPWSTFDGFNLNLQKGYDYLIPIFTMGKIIKKDNKIILPLAIQVHHAVCDGFHICRFVNELQELIIVTQVCL
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase, CAT.
What is the protein family that this protein belongs to?
Belongs to the chloramphenicol acetyltransferase family.
Protein: CYNS_VITVI
Sequence: MEESKSSVASRLMSVKRTSGKSYGRIAEETGLTNVYVAQLLRRQAQLKADTAPKLQAALPELTDELLQEMMKPPLRSYDPHLIQEPTVYRLNEAVMHFGESIKEIINEEFGDGIMSAIDFYCSVDKVKGVDGKDRVVLTFDGKYLPHTEQKSEHMVSRLRLQGD
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: MDH_ECODH
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: CTPAL_STAAB
Sequence: MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILIGTILITAVITVVAYIFINQKINGLNKTDQANLNKIENVYKILNSDYYKKQSSDKLSKAAIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPAERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREKIHVKSVEYKKKGKVGVITINKFQNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLDEAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDALKEAKDMDISILVNEGSASASEVFTGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPDVTIDTPKYQSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQVKAFQQTNKLEVTGEFNKETNNKFTELLVEKANKHDDVLDKLINILK
What are the official names of this protein?
Probable CtpA-like serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CAIC_ECOLC
Sequence: MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLCEESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATVTECIPMMIRTLMVQPPSANDQQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRVGFCYEAEIRDDHNRPLPAGEIGEICIKGIPGKTIFKEYFLNPQATAKVLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIAAHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
What is the function of this protein?
Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle.  Also has activity toward crotonobetaine and gamma-butyrobetaine.
What are the official names of this protein?
Crotonobetaine/carnitine--CoA ligase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: EDNRA_HUMAN
Sequence: METLCLRASFWLALVGCVISDNPERYSTNLSNHVDDFTTFRGTELSFLVTTHQPTNLVLPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNHDQNNHNTDRSSHKDSMN
What is the function of this protein?
Receptor for endothelin-1.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
What are the official names of this protein?
Endothelin-1 receptor, Endothelin receptor type A, ET-A, ETA-R, hET-AR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DPO3_HALH5
Sequence: MNEEQRVRQERFKLLMEQLLIPEDVTANHLKDGKIEKLTIKKDERRWHFQLSIPTVLPASIYELLADRLVQTFSHIAKVSFQIQYGQPDLSEQVWQSYWPLIVAKLTNISQPLKEMLEKQTPRFDGKRLVIQVGNETEAIALKRKLTEPLQQAVQSFGFPAVQLDAEVKESKQAFEKFVEQRKQEDHSKVVEAILEKKKLEQQVEKKMKEEKLTIGYPIKDEPVPLETIVEEERRITVQGYIFAAETKELRSGRTLLTFKITDYTDSILVKMFSRDKEDIPLLQAVKKGMWVKVRGGVQNDTFVRDLVMIANDVNEVSGKETKDEAPDDEKRVELHLHTAMSQMDGISSAGAYVTQASKWGHKAIAITDHGVVQAFPEAYGASQKHGIKVIYGVEANLVDDGVPIAYNEAHIPLLDSEFVVFDVETTGLSAVYNKIIELAAVKVKNGEIIDRFERFADPHEPLTNTIIELTGITDDMLKGQPEVEQVLNEFHAFIGDAVLVAHNASFDMGFLNTGFQKMGLGEAKNPVIDTLELGRFLYPTLKNHRLNTLCKKFDIELVSHHRAIYDAEATGHLLWRMVKDATERDILYHDQLNDNMGEGNFHRQRPSHCILLAQTQEGLKNLYKLVSMAHVEYFYRTPRIPRSQLQKHREGILVGSGCDKGEVFEGMMQKTPQEVEEIAKFYDYIEVQPLANYEHLIEKELVKSREALQEIVANIVKLGEQLGKPVVATGNAHYLKEEDYIYRKILIASQGGANPLNKQTLPQVHFRTTSEMLEAFAFLGEEKAKEIVVTNTNHIADQIEEIHPIPDKLYTPKIEGADEEIRQMSYNRARKIYGDPLPEIVEARLEKELKSIIGHGFAVIYLISHKLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYVCPNCHHSHFFNDGSVGSGYDLPDENCPKCGTPYVKDGQDIPFETFLGFKGDKVPDIDLNFSGEYQPRAHNYTKELFGESYVYRAGTIGTVAEKTAYGYVKGYQSDHDLHFRGAEIDRLVTGCTGVKRTTGQHPGGIIVVPDYMDIHDFCPIQFPADDRGAEWKTTHFDFHSIHDNLLKLDILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFSGPDVLGVTEEQILCKTGTLGIPEFGTRFVRQMLEETKPSTFSELVQISGLSHGTDVWLNNANELIYNGTCELKDVIGCRDDIMVYLIYKGLEPSLAFKIMEFVRKGKGLQPEWIEEMKKHDVPDWYIGSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHYPILYYASYFTVRADDFDLDTMVKGSAAIRAKIEEINGKGLDASPKEKSLLTVLELALEMVERGFSFQKVDLYRSEATEFLVEGNTLIPPFNALTGVGTNAAINIVKARDEREFLSKEDLQQRSKITKTVLENLDAHGCLEGLPESNQLSLF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
Protein: XPT_ALKCK
Sequence: MELLKEAIRKRGSVLSSGVLKVDQFLNHQVDTNLMSAIGEEFARLFADEHVTKVVTIESSGIAPSFMCAHSLQVPLIFARKKKSVTMDKENVYSSRVYSFTKKEYSEVTVSKDWLCPGDRVLIIDDFLANGQAATGLTQIVEEAGATVAGIGIVIEKSFQDGRALLEGKGYRIESLARISSLEGNKVQFVEESAHFAYNKS
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1024_SYNY3
Sequence: MSFFSHHPSRSPRIWTDILLRWQGSVIPAIASRVLVCMAFSLGVTLVDGWGYKFSIPIQESIVPSIVLGLLLVFRTNTAYERFWEGRKAWGTMVNTIRNLSRIIWVSVAEPSPQAHQDKIKILHLLVAFAVATKLHLRSQPLNEEIWALLPESGYRKLEDLNNPPLEIAFWISNYLQREYDQNNINAYQLTAMLRLVDTMVDVLGSCERILKTPIPLAYAIHLRQLIFLYCFITPFQIVNTLHWATAFVVGIIAFTVFGIEEIGVEIENPFGHDANDLPLDQICQTMQANLEDLIQLPPWHQISHGD
What are the official names of this protein?
Voltage-dependent anion channel-forming protein sll1024.
What is the protein family that this protein belongs to?
Belongs to the anion channel-forming bestrophin (TC 1.A.46) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSMD5_DROME
Sequence: MEMEDNWWVTKLKALESKPQRLDALTAMNSAIAKEAALPRQIIERLLTTDQLYDCANPAADSHVPKDQAVDVTLELLCHCLDQLAMDTADEQLSSLLRRGLTHSNPALRAQVLASLFKKLLRQLTVGQVLTLPNNELIFLILDELKQPDTQSTSLAINILSIVLPQRISNADVQAKLVQLLKQNEIVRCRAYELAVVLAKKSATLLSDVTFILDAALSELDNDDVLLQASVMELLVPLAEQNHGLSYMERRRVLDIISYRVQRVEEHPLDALLVPSIMKFFGKISVYQPLKIIGGYPHMLACLFMQLQSEDESILPTAMDTLANLATTPQGKILLNMHFSGAMEKSFKKYGSHTKKLSAHIKKRLLNSLDVIYDFKTPPATEIINIGKNWYECFAGGAHANIIMDLINTPFPDLQMAALSFLKTICKYNWGIVALKNTGGAVEFLLSRQKDLHRDIKYMKWQIMEILSASAEFSPTETIRFTAYVNEGPYHVQADLDVATEPQGNA
What is the function of this protein?
Acts as a chaperone during the assembly of the 26S proteasome.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 5, 26S proteasome subunit S5B, dS5b.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5B/HSM3 family.
Protein: FABV_TERTT
Sequence: MIIKPKVRGFICTNAHPKGCAANVQAQIEYTQAQGKIENGPKNVLVVGASTGYGLASRIVAAFGCGAKTLGLFFEKPGTERKTGTAGFYNVAAFQQAAEKAGLWSKNMNGDAFSHEAKSKAIDVIKAEMGKIDLVVYSLASPRRQDPDSGEVYSSVLKPVGQAYTSKNLNTDTLKITETTLDAASDEEIAQTIKVMGGEDWELWMNALAEADVLAEGCKTVAYTYLGEKITWPIYGKATIGKAKEDLDRAATAIASAHSEKNISANVAVLKAVVTQASSAIPIMPLYLSALFKVMKANGTQEGCIEQLNRLFTECLYSDSPRLDDANRFRVDEKELSPEVQAGVEALWGEITEENLLEISDFKGYQQEFLGLFGFGVDGVDYEEDVDPNVALALVE
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: PPN1_CANGA
Sequence: MAVNEKDVGRKSRVSVVLWVFIALGTLFLCKNAFTFSSESIHGLKISSDDSDSVDIERQISLGLTPRKPVVITDLRTGNKRKLHGRFLHITDMHPDEYYVAGTSIDNVCHSGEPTKGKDRAAKFGNAMSGCDSPMLLMDMTLDWIDKNLKDQIDFVVWTGDNIRHDNDRTYPRTEDEIFRMNAEVAEKIKKIFRTPNSPDPRDFAVPVVPSIGNNDVFPHNLFSLGPTLQTREYYRLWGDFIPEEQQRMFDRDASFFTEVIPGKLAVLSFNTLYLFKANPLVDNCDSRKQPGYQLLLWLGYVLDEIRERGMKVWISGHVPPIAKNYDSSCYDKFSLWMHEYRDVIIGGLYGHMNMDHFVPVDVQAIRENMEEQQMSLLSEDERLTKTIREHAIAAREAHLMGAKPVNKESYLDGVLDTYYKGVLQEIEQAVDSDLDIEKKKKKKGKKKKGKKEKRTLEEIYDQHSIVQVSGSVIPTFNPSIRVWEYNISDITDSSSIFGENQLEYQSWDLFFEDLEHKMKNEFDDNESSFWAASAEQNKKKKKKNGKPDKSIPRKKPDELPAGPGHIQQLFSPTKFVQYFADLDSINSEYEKLIDKGLAEHDAINKAFNYEVEYTSKDEPYPMESLLVKDYLHLAADLARDNGLWKIFKERAFISTGYEDERN
What is the function of this protein?
Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
What are the official names of this protein?
Endopolyphosphatase.
What is the protein family that this protein belongs to?
Belongs to the endopolyphosphatase PPN1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein.