PharMolix/UniProtQA huggingface dataset:
Protein: SCR_APIME
Sequence: TVNANGEVKRQRTSYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKEHKMASMNIVPYHMSPYGHPY
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein H55.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Deformed subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL33_GRABC
Sequence: MAKSNTVQIKLVSTADTGFFYVTKKNARAQTGKLEFRKYDPVVRKHVTFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SYM_STRP7
Sequence: MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYVSGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIVQELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAILDPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTKRYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNITDFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSNNWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRTLKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKFYDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWNYISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_BACVZ
Sequence: MRSFFVTGTDTGVGKTIVSCGLAAAFRQKQADIGVFKPFLSGVPRTHPESDTSLLKDMSQTALSHEEITPFEWKEPLAPYTAAMLEGKSVSMADVMAHWSKIKNRHECFIVEGAGGISVPLGENYLVSDLIKAMELPAVIVTRPDLGTINHTYLTVEYAKNMGIEVLGIIINGVRSRPGLDEKTNPSMIETLCKVPILGITPKLDHVSSENIQHMIEKHIDVSSFMNLTQMGR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMCY_PARVE
Sequence: MISAKTLRPAIAAIALFAIGATGAWAQDKITVTSEKPVAAADVPADAVVVGIEKMKYLTPEVTIKAGETVYWVNGEVMPHNVAFKKGIVGEDAFRGEMMTKDQAYAITFNEAGSYDYFCTPHPFMRGKVIVE
What is the function of this protein?
Primary acceptor of electrons from methylamine dehydrogenase.  Passes those electrons on either a soluble cytochrome c or to pseudoazurin.
What are the official names of this protein?
Amicyanin.
What are the subcellular locations of this protein?
Periplasm.
Protein: GCSH_PROMA
Sequence: MIFDFPKKFRFADSHEYACPEGDLVRIGISAFAVDQLGDIVFVDLPGIGTLLEQGISFGSVESVKAVEDMNAPIGGEVLQINESVLNSPEELQNDPHGEGWLLLVKPSDASQLDKLMSSEIYSEKVSSK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: FABH_SALCH
Sequence: MYTKIIGTGSYLPEQVRTNADLEKMVETSDEWIVTRTGIRERHIAAPNETVATMGFTAANRAIEMAGIDKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALSIADQYVKSGAVKHALVVGSDVLARTCDPGDRGTIIIFGDGAGAAVLSASEEPGIISTHLHADGRYGELLTLPNADRVNPDNPIYLTMAGNEVFKVAVTELAHIVDETLAANNLDRSELDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKAGQLVLLEAFGGGFTWGSALIRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPA_GEOSE
Sequence: MAQLSVEQFLNEQKQAVETALSRYIERLEGPAKLKKAMAYSLEAGGKRIRPLLLLSTVRALGKDPAVGLPVACAIEMIHTYSLIHDDLPSMDNDDLRRGKPTNHKVFGEAMAILAGDGLLTYAFQLITEIDDERIPPSVRLRLIERLAKAAGPEGMVAGQAADMEGEGKTLTLSELEYIHRHKTGKMLQYSVHAGALIGGADARQTRELDEFAAHLGLAFQIRDDILDIEGAEEKIGKPVGSDQSNNKATYPALLSLAGAKEKLAFHIEAAQRHLRNADVDGAALAYICELVAARDH
What are the official names of this protein?
Farnesyl diphosphate synthase, FPP synthase, (2E,6E)-farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_ARCUU
Sequence: MEEFKRDLELDRSQQHDFIYPLIFQEYIYALAHDRGLNRSIVLENPGYDNKSSLLIVKRLIIHLITQMYQQNHFLFSANDSNKKKIVGYNTNFYSQMIFXGFAVVVEIPFSLXLLSSLEGKEIVKSQNFQSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLRFFLHAYHNWNSLMTQKKSSFSFSKKNKRLFLFLYNFHVCEYESIFVFLRNQSSHLRSISSETFLERIYFYRKIELXVFTKDFKAILWVFKXPFLHYVRYQGKSTLASKGTSLLMNKWKYYLVKFWQCYFYMWSQPRRIHINQLSNDSLDFLGYLSSVRLNPLMVRSQMLKNAFLIGNAFXKFDTLVPIIPMIGSLSKAKFGNVLGHPMNXSVWADLSNPDIMDRFXRXFRNLSHYHSGSLKKMSLYRVKYILRLSCARTLARKHKSTVRAFLKRLGVGLLEEFFTEEEQVFYLTFPKASSSSGELYRRRIWYLDIICINELANHS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LNT_PHOPR
Sequence: MTKKSFFSLGRLLLAVPAGAIATLTFAPYNYWLLAPVSIALLLWLLQAQTVKRSGLIGFLWGLGLFGTGISWVHVSIDTFGGMPKIASVFLMSSLISYLALYPAAFGALFNRFNRGRPFHQLMLSGPVIWLLLDWVRGWALTGFPWLWMGYGQIDSPLASLAPILGVEGITLALVLISGALVASVVYRNWKPLMVPVLIMALTWAANTVSWVVPDPTKNLDVALIQGNVPQELKWLPSERWPTLMKYTDLTRENWDADIIVWPEAAIPALEAHLPTFLQNLDSAARNNNSTVITGVLDQKEDGQYFNNILTLGKNAYGPYQYDKATRYSKHHLLPFGEFVPFGDLLRPIAPLFNLPMSSFSRGDLVQPNLEASGYSIAPALCYEVAFSEQVRKNVNIDTDLLLTLSNDAWFGTSIGPFQHMEIAQMRALELGKPLIRSTNTGITAVVDHTGQIIKQIPQFETAVLRATITPTEGLTPYTTLGSWPLYFYSLWSLTLSMILIRRRSGRFRDTRPVETE
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y098_RICTY
Sequence: MCDKIFHNLSGKTLVATPYVITKGIYHKSLIYMLSHTEEGAIGLIFNRLVNHVDLKSFFKIKEDKITSQVIVPIYLGGPIEHEKGFFLHSRDYNKNLLLDFHNDLAVSSNLEISEDIAFGQGPKNSLFIVGYTAWKPGQLEEELEKNLWLVMDCNKEFIFADNPENKWHNALKHLGIDEMYFSSQIGNA
What are the official names of this protein?
UPF0301 protein RT0098.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: ARF_CRYNJ
Sequence: MGLSVSKLLNGLFGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGIIFVVDSNDRERITEAREELQRMLSEDELRDALLLVFANKQDLPNAMNAAEITDKLGLHSLRQRSWYIQAACATSGDGLYEGLEWLSANLKRKSP
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: RUVA_CLOAB
Sequence: MYEYIKGKYIGINKDYIIVDNNGVGYKIFTSGNTMANMPKPEEDVLIYLTQIVRQDFIGLYGFLTKDELEMFNKLLTINGVGAKASLSLLSICTVNNLKYAIITGDEKTIVKAPGIGKKTAQRIILELKDKFKSTDISKGNSEINNLDVDYDEHSKKLEEVRFALNSLGYSEKETDRAINNVDKSEGIENIIKSCLRFLMN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RFCL_NATPD
Sequence: MSDWTEAYRPTTLSEVRGNNKARDAFEEWAKAWEDHREAVILHGSPGVGKTSAAHALANDMGWPVLEMNASDARTKDEIERFAGRAASNATLGGGRQLIILDEADNLHQHKDRGGAAAMTRLVKDATQPVVLIANDYYEMSSGLRSACRDVEFRDVSARSIVPVLRDICRQENVEFDEDVLQEIAEANRGDLRGAVKDLQARERDGEIKPEGSEGSRDRTEDIFAFLDAVLKEESAEEALQTAYAVDETPDNLLQWIEDKVPKVYEGDELADAYEHLADADVWLGRVRATQNYSYWRYATDNVAAGVAAVRQEDRGGWTRYGGAPYRSSRDSTRDYIATRIAESAGVSTATARREILPYLSAMTHHCNNRELTVRMTARYELDAEHVAFITGSGKTTNKVQGIVEDAETRRETAAVDHGGGIFAPAVDDAQSDTESDDDDDGDTLAAFGADEPKEESVNREQSDGTADAEESDDGQAGLSDFM
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: TARI2_STAAB
Sequence: MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNVNGINNNDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVRNEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: AB52G_ORYSJ
Sequence: MDDAGEICSFSRSSSSAREDDEEDQRWAALEKLPTYDRARTALLAMPPDGELREVNVQRLAAVERRALLQRVAGVADDHARFLAKFKERVDRVGIKLPTVEVRYENLNIEAESYVGRRGLPTILNTYTIIMEGLTNALCITKKITHKIPILHNVSGIIKPHRMTLLLGPPGSGKTSLLLALAGTSTLKVSGTITYNGHSMEEFVPQRSAAYVSQHDVHMAELTVRETVNFAAKCQGVGHHYDLLMELLRREKEQNIKPDPEIDIYLKAATTGEQKAEVVTNHILKILGLDICADTIVGNNMLRGISGGQKKRLTTAEMIVTPGRALFMDEISTGLDSSTTFQIVNTIRQTIRILGGTAVIALLQPAPETYELFDDIILLSDGQVVYNGPRDHVLEFFKSVGFKCPERKCVADFLQEVTSRKDQKQYWIGSDDTYQYVPVTMIAEAFQSFHVGQAIRSELAIPFEKSKNHPAALATSKYGVSMKELLKANIYREILLMKRNSFLYIFKAIQLKLVAINAMTVFIRTNMYRDSIENGRSYMGALFYGMMMIVYSALAEMGPAIAKLPVLFKQRDLLYYPSWTYSLPSWIIKIPISFLNTTVWVFLTYYVIGFDPNVLRFFRQFLVLFVLCEVIYALFRFIVALTRHPVIASNMGPFCILIFMLSCGFILTRDDVKKWWIWLYWISPLMYALNALAVNEFLGQIWNKSILGYKGPLGRLVLGSSSFLPETKWYWISIGALLGYVLLFNVLYTICLTFLTHAKEIINDEANSYHATRHSSAGNKGMVLPFVPLSITFEDIRYSVDTPEAFKAKGMTEGRLELLKDISGSFRQGVLTALMGVSGAGKTTLLDVLAGRKTSGYVQGSITISGYPKKQETFARISGYCEQNDIHSPNVTVYESLMFSAWLRLPVEIDSATRKMFVYEVMELVEILSLKDALVGLPGVSGLSSERRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRAIRNTVDTGRTVVCTIHQPSIEIFESFDELFLMKQGGEEIYVGPIGRQSCELIKYFEAIQGVSKIKDGYNPSTWMLEVTSTTQEQRTCVDFSQIYKNSELYRRNKNLIKELSAPPEGSSDLSFPTQYSQLFLTQWLACLWKQHLSYWRNPPYIVVRYLFTIVVALLFGTMFWGIGKKRQNQQTLFSIMGAMYSACMAMGVQNSSSVQPAIFVERTIFYRERASHMYSALSYALGQVAIEFPYIFLQTIIYCVLVYAMVGYEWTCAKFLWYLFFMFFTLSYFTFYGMMMAGLTPNNAMSAVVSTAFYNIWNLFSGFLIPRIRIPVWWRWYYWMCPVAWTLNGLLTSQFGDVNDKFNNGVSVSDFIESYFGYKQDLLWVAAVAVVSFAILFAFLFGLSLRLFNFQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 52, OsABCG52, Pleiotropic drug resistance protein 18, OsPDR18.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ALKB_SALTY
Sequence: MLDLFADEAPWQEPLAPGAVVLRRFAFRAAQSLLDDIGFVASQSPFRQMVTPGGYTMSVAMTNCGALGWTTDRHGYCYAVRDPLTDKPWPALPLSFASVCRQAAIAAGYASFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGVPAVFQFGGLRRSDPIQRILLEHGDIVVWGGESRLFYHGIQPLKAGFHPMTGEFRYNLTFRQAAEKE
What is the function of this protein?
Dioxygenase that repairs alkylated DNA and RNA containing 3-methylcytosine or 1-methyladenine by oxidative demethylation.  Has highest activity towards 3-methylcytosine.  Has lower activity towards alkylated DNA containing ethenoadenine, and no detectable activity towards 1-methylguanine or 3-methylthymine.  Accepts double-stranded and single-stranded substrates.  Requires molecular oxygen, alpha-ketoglutarate and iron.  Provides extensive resistance to alkylating agents such as MMS and DMS (SN2 agents), but not to MMNG and MNU (SN1 agents) (By similarity).
What are the official names of this protein?
Alpha-ketoglutarate-dependent dioxygenase AlkB, Alkylated DNA repair protein AlkB, DNA oxidative demethylase AlkB.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
Protein: AMPP1_PARBP
Sequence: METVDTSQRLARLRELMKERNVDVYLVPSEDSHQSEYIAPCDGRREFISGFSGSAGCAIVSMTKAALSTDGRYFNQASKQLDNNWLLLKRGIESMPTWQEWTAEQLEGGKVVGVDPSLITASDARSLSETIKKSGGSLLGVQENLVDLVWGKDRPCRPSEKVTVHPVEFAGKSFEEKITDLRKELEKKKSAGFVVSMLDEVAWLFNLRGNDIPYNPVFFSYAIITPSTADLYIDEEKLSADVKKHLGDKVSLKPYTSIFEDAKALGQSAQAEVNGGASDPPRKFFISTKASWSLSLALGGANKVEEVRSPISDAKAIKNDTELEGMRACHIRDGAALTKYFAWLENELVNKKTVLNEVEASDKLEEIRSKQKNFVGLSFDTISSSGPNAAVVHYKAERKNCSIIDPEAVYLCDSGAQYLDGTTDTTRTLHFGEPTEKERKAYTLVLKGMIAIDTAIFPKGTTGFSLDTLARQFLWKEGLDYLHGTGHGVGSYLNVHEGPIGIGTRVQYSETPLSVGNVISDEPGYYEDGKFGIRIENIIMAREVKTTFSFGERPWLGFEHVTMTPLCRKLIDPSLLNDAEKKWINEYHSEVWEKTSGYFAEDELTRNWLKRETQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: METK_METJA
Sequence: MRNIIVKKLDVEPIEERPTEIVERKGLGHPDSICDGIAESVSRALCKMYMEKFGTILHHNTDQVELVGGHAYPKFGGGVMVSPIYILLSGRATMEILDKEKNEVIKLPVGTTAVKAAKEYLKKVLRNVDVDKDVIIDCRIGQGSMDLVDVFERQKNEVPLANDTSFGVGYAPLSTTERLVLETERFLNSDELKNEIPAVGEDIKVMGLREGKKITLTIAMAVVDRYVKNIEEYKEVIEKVRKKVEDLAKKIADGYEVEIHINTADDYERESVYLTVTGTSAEMGDDGSVGRGNRVNGLITPFRPMSMEAASGKNPVNHVGKIYNILANLIANDIAKLEGVKECYVRILSQIGKPINEPKALDIEIITEDSYDIKDIEPKAKEIANKWLDNIMEVQKMIVEGKVTTF
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase 2 family.
Protein: PROB_CAMJ8
Sequence: MKRIVVKVGSHVISEENTLSFERLKNLVAFLAKLMEKYEVILVTSAAISAGHTKLDIDRKNLINKQVLAAIGQPFLISVYNELLAKFNKLGGQILLTGKDFDSRKATKHAKNAIDMMINLGILPIINENDATAIEEIVFGDNDSLSAYATHFFDADLLVILSDIDGFYDKNPSEFSDAKRLEKITHIKEEWLQATIKTGSEHGTGGIVTKLKAAKFLLEHNKKMFLASGFDLSVAKTFLLEDKQIGGTLFE
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_SERP5
Sequence: MQQHYQFDAIVIGSGPGGEGAAMGLVKQGARVAVIERYNNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYNNSRTLSATFPDILRHADNVINQQTRMRQGFYERNQCKLFAGDARFIDANTVSVSYMDGTQDTIRADHIVIACGSRPYNPSSVDFNHPRIYNSDSILELNHEPRHVIIYGAGVIGCEYASIFRGLNVKVDLINTRDRLLAFLDQEMSDSLSYHFWNNGVVIRHNEEFEKIEGTDDGVIVHLKSGKKVKADCLLYANGRTGNTDSLGLENVGLESDSRGLLKVNSMYQTALSHIYAVGDVIGYPSLASAAYDQGRIAAQAIASGEASGHLIEDIPTGIYTIPEISSVGKTEQELTAMKVPYEVGRAQFKHLARAQIAGMNVGSLKILFHRDTLQILGIHCFGERAAEIIHIGQAIMEQKGEGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAPD_SHIFL
Sequence: MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELTEGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE
What is the function of this protein?
Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
What are the official names of this protein?
Peptide transport system ATP-binding protein SapD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYI_METB6
Sequence: MKEVTANFSAKDIEREVQEYWRTHDTYKAVKEQHSAGRAFFFVDGPPYTTGQIHLGTAWNKIIKDSILRYHRMNGRNVIDRAGYDMHGLPIEVKVEQKLGFASKKDIETFGIEKFINECREFAIKNKELMDAQFENLGIWMDFKNAYQTIKPWYVEAAWWTLAKAQEKGMLERGYRVVNWCPRCETAIADAEVEYWDETDPSVFVKFPIRGKVSESLVIWTTTPWTLPANVAVAVGKEFVYARVHAEKNGREEYLWVAEDLVKSVLKKGRYQKFETLETKKGAELIGWEYDSPLMDVVPIQKEIAHRVVAADFVAMENTGMVHIAPGHGWDDYVLGTKEKLAIVCPVDGAGKFRPETGIFAGKFVRDANGEVLDALGERLLATEKITHRYGHCWRCKTPIIFRATSQWFLKASEMRDLMLSEVKKVTWYPEWAGSARFYDWIKEARDWCVSRQRYWGIPIPVWICDKCDKYRVIGTIAELEKASGQKVPDPHRPFVDQVTIPCECGGTMKRVGDIFDVWFDSAVASWATVGFPAKTDEFEKLWPADFITEGQDQTRGWFYSQLGASTIAFGKAPYKSVCMHGFALDAEGRKMSKSLGNVVAPEEVIAKVGVDVLRLYVLSSSAPWDDLKFNWDGIATVNRTMNILWNVYRFPMPYMILDRFEPEAKSGHWDGSFVRSHIRELPDEDRWIVSRINTVAGIVDASTKECQLHRATREILNFILEDLSRWYVQLVRPRMWLEGESEQKIFAYETIYYVMRRLVDLMAPFAPHITEEIYSNLRCKNDPGSVHMLDWQACDDALTNRELEHAMELVRSFDDAVQNARQAGKRKLRWPVDEVVIVTAKPEVKDAVARLNEVCMDRANARKVTVVIGRWDRIGWHAEPVMKALGKGFGKNSFAVKGLIEAADGNAIKAAVDAGQKFQLKIEEGKISKPDDLKIGTDYEQDVVEIGIEHVRFTEKLPTDIFSAPMEDGTVYVDVALTPDLEAEGYAREIIRRIQEMRRQLDLAVEDFIMVDVAVADKRICELVGASWKPGIADEVRAKTLSLHHSAEPAGSSHQLAKDWDVEGIAMTIGISKVA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_MANSM
Sequence: MTAQVISGSALAKKVKTEVGQKIEQYVAQGKRAPGLAVILVGADPASQVYVGSKRKSCAEIGINSKSYDLEESTSEAALLTLIDELNNDADIDGILVQLPLPKHIDSTKVIERIAPHKDVDGFHPYNVGRLCQRIPTLRACTPYGIMKLLETTELNLKGRHAVIVGASNIVGRPMAMELLLAGCTVTVTHRFTTNLEGYVRQADILVVAVGKAEFIPGNWVKEGAVVIDVGINRCEDGKLRGDVEFAAAAEKAGFITPVPGGVGPMTVAMLMFNTLTAYENNG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y325_CUPTR
Sequence: MRIILITGISGSGKSVALNVLEDAGYYCVDNLPAQFIPELTRYLDAQGYTHLGVATDIRSRESLDQLPDTVRALAAEHQVEVIFLTASTDALVQRYSETRRRHPLSARTDGAAGGGAFNDTALMEAIEMERSLLSPLAEAAHRIDTSNVRTNTLRSWIKELIRDDSQRLTLLFESFGFKHGVPSDADMVFDVRSLPNPYYDLALRPLTGRDTPVIDFLQGQPMVLAMAEDIRAYVEKWLPSFIADNRSYLTVAIGCTGGQHRSVYIAERLANYFRAHGNVLVRHRELAPAG
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein RALTA_A0325.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: TFE_METTP
Sequence: MVAVENPIHRAYLLKIVGEEGLRIVEAMPEEEVTDEHLAEITGISLNTVRKSLYLLYEHRLAIYRRKRDPESGWLTYLWKICPESLDSALEAEVRKLINKLNARLRYEKDHVFYACVNGCARFVFEEASENNFTCPFCQGSLEYMENSTIVEVIEERIKELSAALCS
What is the function of this protein?
Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment.  Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal.  It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes.  Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.
What are the official names of this protein?
Transcription factor E, TFE, TFIIE subunit alpha homolog, Transcription initiation factor TFIIE.
What is the protein family that this protein belongs to?
Belongs to the TFE family.
Protein: EAF3_CRYNB
Sequence: MAGAVPQFMVDEYVLAYHGPLLYEARVILAEVWDESNTLLGTVGPHYFIHYKGWKQTWDEWVPESRLLKLNEAGFAKRRALLDAQAKKGRSTGGSGGTGSPGAGKGGLKDKKKDTKKRGRDAMESESDFMKRPEVKIVIPDVLKLVLVDDWENVTKNNQLVALPRKPNVRELLEEYRQYASASKKQERSDRATALLSEIISGITLYFDKALGNNLLYRFERAQYVEQKRQNPEKPMSEIYGAEHLLRLFVNFGPFIAYTNIDTESLNILRDYINDIMQWMIKEQKRLFMKEYEETTTHYQNLSRS
What is the function of this protein?
Involved in deacetylation of histones, chromatin assembly and chromosome segregation.  May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF3.
What is the protein family that this protein belongs to?
Belongs to the MRG family.
What are the subcellular locations of this protein?
Nucleus.