PharMolix/UniProtQA huggingface dataset:
Protein: HUT1_ASHGO
Sequence: MGSQVRLVIAVCGIYATFLTWSLAQEPLTTSVWPNSAARFSHSSFIVLCQALTAAVVGLCYLKAQRSGYGAREFIRKHWADVAGISLTQALSAPAANHSLQYVDYVGYMLAKSCKLLPIMLVHVLVYRTPIGRDKALVGVLVSGGVALFTLGGAERKQGEASLYGLGMLLVSLFLDGLTNASQDRLLRRPASKKITGAHLMVALNTAIVLWNLAYLVLFDRTQWQGSLQQLHADPAILTYLFTYCACGALGQCFVFFTLEHYSSLVLATVTVTRKMVSMLLSIVVYGHSVRPVQWLGILVVFGGIIWETVKKGQRGSGQKSKQH
What is the function of this protein?
May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen.  Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).
What are the official names of this protein?
UDP-galactose transporter homolog 1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CAOG1_ARATH
Sequence: MAEPSFARLFLLFFSFLLIFATYSWVFGPDSGFLFGTRVRKTLGSNRQVHVDHSLEKPHHPLDPLTVREINRVRTILSNHDPGFGSGSATIHSMALDEPEKSRVVQWKKGNKLLSRRAAVVAYWGGQTHEITVDLDSGRVVSDVINRTSGYPILTLNDVFAASQVPLKSLEFNRSIEARGVKFSDLACITPFAGWFGSEEEGRRVIRVQCFTLQGTTNYFMRPLEGLYVTVDLDKLEVIKIIDKGPIPIPKASGTEYRFGVQNKPVHMDRINPISMEQPDGPSFRVEDGHLVKWANWVFHVKADQRAGMIISQATVRDSETGEPRSVMYKGFPSELFVPYMDPEEGWYYKGYMDAGELGLGPTAMPLVPLNDCPRNSYYIDGVFASPDGKPIVQPNMICLFERYAGDISWRHSEILFANADIRESRPKVTLVARMATSVGNYDYIFDWEFQTDGLIRVTVAASGMLMVKGTPYDNVDDLGDREDDAGPLISENVIGVVHDHFITFHLDMDIDGPMNNSLVKVHLEKQRVPTGKSPRKSYLKVKKYIAKTEKDAQIKLSLYDPYEFHIVNPNRKSRVGNPAGYRIVPGGNAASLLDHDDPPQIRGAFTNNQIWVTPYNRSEQYAGGVLIYQSQGDDTLQVWSDRDRSIENKDIVLWYTLGFHHVPCQEDYPVMPTVAASFELKPANFFESNPILGSAPFFEKDLPVCRPFASS
What is the function of this protein?
Copper amine oxidase that can use putrescine and spermidine as substrates (PubMed:23915037).  Required for abscisic acid- (ABA) and polyamine- (PA) and H(2)O(2)-dependent induced nitric oxide (NO) biosynthesis (PubMed:21471330).  Involved in ABA signal transduction and in responses to osmotic stress (PubMed:21471330).
What are the official names of this protein?
Amine oxidase [copper-containing] gamma 1, AtCuAO1, AtCuAOgamma1, Copper amine oxidase 1, Primary amine oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: SYT_RICAH
Sequence: MINISFPDGSVRQFENDITAYEVANAISMSLAKAAMVAEINGELKDLSTVIENDCKLRILTAKDSECLEIIRHDAAHIIAEAAKELFPDIQVTIGPAIENGFFYDFAKDKPFTPDDVAMIEARMHEIVKRNEQITRELWNRDKAIEFFKSIGEHYKAEIIASIPAGEQITLYRQGNFIDLCRGPHAPSTGFVKHFKLMKVAGAYWRGDSRNEMLQRIYGTAWATKEQLDNYLLMLEEAEKRDHRKLGKELDLFHFQEEAQGMVFWHDKGWSIYNTIEQYIRKKIRKNGYTEVKTPVLVDKSLWEASGHWEKFRDDMFALDTDDKTLALKPMNCPCHVQIFKQGIKSYRDLPLRMSEFGLCHRNEASGALHGLMRVRSLVQDDAHIFCTEEQITDETVSFCKLLTEVYKDFGFTNISVKFSDRPEVRAGSNGTWDKAENALKEAVEKAGFTYTLNPGEGAFYGPKLEFVLTDAIGRQWQCGTLQMDFVLPERLDASYIAASGEKKRPVMLHRAILGSLERFIGILIEEYAGCFPLWLAPIQVAIATITSDLNDYALEVQKALIDNGVRTDINISPDKINYKIREFYNQKIPMIAVIGKQEQENKQVTIRRLRTTEQEVLSLEQLITLIKEENEKYL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADE_PSEPK
Sequence: MYDWLNALPKAELHLHLEGSLEPELLFALAERNKIALPWADVETLRGAYAFNNLQEFLDLYYQGADVLRTEQDFYDLTWAYLQRCKAQNVIHTEPFFDPQTHTDRGIAFEVVLNGISQALKDGREQLGISSGLILSFLRHLSEDEAQKTLDQALPFRDAFIAVGLDSSEMGHPPSKFQRVFDRARSEGFVAVAHAGEEGPPEYIWEALDLLKIKRIDHGVRAIEDERLMQRIIDEQIPLTVCPLSNTKLCVFDHMSQHNILDMLERGVKVTVNSDDPAYFGGYVTENFHALHTHLGMTEDQARRLAQNSLDARLV
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: MX1_PHOVI
Sequence: MVNSKGEITDSDPGSNHLLLNGLPDKAGKNQDTEPENSLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLLNEDEWRGKVSYQDFEMEISDPSEVEVEISKAQNVIAGEGQGISHELISLEVSSPHVPDLTLIDLPGITRVAVGNQPADIGRQTKQLIRKYILKQETINLVVVPCNVDIATTEALSMAQEVDPSGDRTIGILTKPDLVDRGTESKVVDVAQNLVCHLKKGYMIVKCRGQQDIQDQVTLTEALQKERDFFEDHPHFRVLLEEGRATVPCLADKLTSELITHICKTLPLLENQIKENHEKITEELKKYGSDVPEEEHEKMFFLIEKINAFNHDINSLIEGEEFVGEDESRLFTKIRNEFHKWSCVIEKKFQQGYKAIYKQIEKFENRYRGRELPGFVNYKTFEIIIKQQIKELEEPAVYMLHMVTDMVQAAFTDISEANFAEFFNLYRTTKSKIEDIKFELEKEAEKSIRLHFQMEQIVYCQDQVYQRALQRVREKVADEEKNKKINSMSSEEVSSVNISLSEIFEHLLAYRQEATNRISSHIPLIIQYFILQAYGQKLQKGMLQLLQDKDTYNWLLKERSDTSDKRKFLKERLSRLAQARRRLAKFPG
What is the function of this protein?
Interferon-induced dynamin-like GTPase with antiviral activity.
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx1, Myxoma resistance protein 1, Myxovirus resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region. Note=Binds preferentially to negatively charged phospholipids.
Protein: PAP1_CAMPM
Sequence: MNRNPDHNTLPNITLKIIETYLGRLPSVNEYYMLKLQTRNIQKITVFNKDIFVSLVKKNKKRFFSDVDTSASEIKDRILSYFSKQTQTYNIGKLFTIIELQSVLVTTYTDILGVLTIKAPNVISSKISYNVTSMEELARDMLNSMNVAVIDKAKVMGRHNVSSLVKNVNKLMEEYLRRHNKSCICYGSYSLYLINPNIRYGDIDILQTNSRTFLIDLAFLIKFITGNNIILSKIPYLRNYMVIKDENDNHIIDSFNIRQDTMNVVPKIFIDNIYIVDPTFQLLNMIKMFSQIDRLEDLSKDPEKFNARMATMLEYVRYTHGIVFDGKRNNIPMKCIIDENNRIVTVTTKDYFSFKKCLAYLDENVLSSDILDLNADTSCDFESVTNSVYLIHDNIMYTYFSNTILLSDKGKVHEISARGLCAHILLYQMLTSGEYKQCLSDLLNSMMNRDKIPIYSHTERDKKPGRHGFINIEKDIIVF
What is the function of this protein?
Polymerase that creates the 3'-poly(A) tail of mRNA's.
What are the official names of this protein?
Poly(A) polymerase catalytic subunit, Poly(A) polymerase large subunit, PAP-L.
What is the protein family that this protein belongs to?
Belongs to the poxviridae poly(A) polymerase catalytic subunit family.
Protein: RTC1_LACTC
Sequence: MSRSQSPSLNDGLSTSNSRHSSSHSRFSLHKAFPQLSGNASFNGTSPKTKLPSRFSGGSNPPYMDSLKEQESSSSSSRSNFRRANYVNPGRIRSSGLKYSLQAPKELSSIDKINDPASRSIVISGKNHLGLYRFREDYGKLELTLDLFNIDQKAASLRTTTRKTSTISDVKAGFHNYKNYVAICGTSTSVSIYDINRANLVDGPASMVLSKHTRSINSVDFNMAQTSLLISGSQDGCIKVWDLRSSQGRKNKSDLTINSGSDSVRDVKWMPTYDFPNNDDVVAGPSNRSHRFASIHDSGLLLTYDLRQPSQAEKRINAHSGPGLCLSWHPTLDYIMTGGRDGKCCLWNMGSKPLNPASFQNIHHNSSFSTSAASSFTQGFSANSVTNFINSPEAVVNTAHPLTKLKFRPSAIPEVFDSVIALSSLGENSDVSLYSLSRSYIPKNVLTTNSPSCGFVWWNENLIFNIDKQNMVTGWDLGKEPTVLDNLPKNKIAWRDIEGDGLVFLAQDKGGYESGGPDGMSVSTETRNFSQSRLSTTTMSNLFPSHTMRQNSSVSSFPALNTHSNSGANLGDRPSLPRTVTSYSKGAYTQTYGSYNTHSSHHNSAASASASSIATELGSEHVLSPRMISLDLPHILNSIRSAKIENYAKKPSRPGSAAFKDSPVEVFKFLSRELKFSYMHDRNFNKPENLTDQDDLAQSVDDNDLKSHLITRFGFSENNTWTKFIKKSNSPEKDAAVENGTKVNEASIEKVTNSPNDTGSDELSSISKLSTEPKKSDLAERNITAIRQRVKHFIELVSMCDHNAEIYLYIDDLSNFKIWMMMRDSLLWELKQITDSLETDGGSLLSESLLVNPDVTRHSNGARKQSMASDYSSFSTSEVGSTTGVQALPEFRGPHSLSTPPRATTSFGAKEPSSLKKRESTIDENLSETEIEAKGLPKEDIKNLRNQISKHQIGDEVAIEDEEEDKFEEKSSAGTDASNKNIPIIPSERKVSFVDQFINSMRSPKTLHGDFETDGSRMANSASTKRSSQPSFSSSLAGLITRRLSDQSPKTKPKDLIYSKSSGSIAKNSSDLFDFQNVEGNNSPRVLTQKSKISMLLKGLKKSETAPPWDASRLIKKIFEQSVATGNVLLTISIILLFQTTFKVTSTTVVKNALSEFINILHKYELFEIAANLLKFCPWDDILEAGNGQCTVRIYCERCKKLLVNESSKEKFTEEWKRTGRQEVMKRFGYWYCDNCSKRNTLCVLCEQPLKKLTFCVLNCGHEGHPECFKKWFMNEEMSECPSGCSGFLL
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RHLB_SHIB3
Sequence: MSKTHLTEQKFSDFALHPKVVEVLEKKGFHNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHADAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEYIEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLTRPRTGNGPRRTGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_SHEDO
Sequence: MSKVTSSTLLKFKQEGTKFTSITAYDASFAAAFDSEGIDAILVGDSLGMVLQGHDDTLPVTTADVAYHTACVRRGISRALLIADMPFMSYATPEQAMTNATTLMQAGANMVKLEGGHWLLETVTMLTQRGIPVCGHLGLTPQSVHVFGGFKMQGKDEKNAQRILDEALALQDAGAQLLVLECIPAALAKTITQAVAIPVIGIGAGADTDGQILVMHDVLGITSGYIPKFSKNYLKQTGEIRSAIKAYIDEVAAGDFPSEEHTLV
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_SULSY
Sequence: MKIDKKYFRKVVNEIIAKTDKSEENLLKISSILDILNKLFKENQTFRNIVLNPKASMEDKEKLMEKVLSALGVDAEISKLLIKIVKDKKANIFKELNKVFKFEVEKFFGTVQGEIISAYKIDEALLNEIKSVIESKIGKKVEFTVKEDNSLIGGAVIKAGTYIIDTSVKSYLKRLESTLSRF
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CEEH2_CAEEL
Sequence: MGFFADLFKVVYSTWRQYIYTTGALLTLTWKWFTEGNEYFVEHVYPEPECLKNWNHKFVQLKNIRMHYVEEGPADGDVLLMVHGFPEFWYSWRFQLEHFKHTHRCIAIDMRGYNTTDRPSGISDYNLTHLVEDIRQFIEILELKRVTLAAHDWGAIVCWRVAMLHSNLIDRLVICNVPHPFAFFEVYNMSKEQRNKSWYIYLFQSQYIPEIAMRSNKMKMLEAMFRGSKAGIRNSENFTDEDMLAWKHVFSQPGGTTGPLNYYRDLFNAPAIPRKLQIVQPKVLILWGDEDAFLDKKGAELSVQFCRDCRVQMIRGASHWVQQDQPQLVNVYMEQFMNEDSYRPIGEIKTFKSHL
What is the function of this protein?
Catalyzes the hydrolysis of epoxide-containing fatty acids.  Active in vitro against trans-1,3-diphenylpropene oxide (t-DPPO), epoxyeicosatrienoic acids (EETs) including 8,9-EET, 11,12-EET and 14,15-EET and the linoleic acid metabolites 12,13-epoxy-9-octadecenoate (12,13-EpOME) and 9,10-epoxy-12-octadecenoate (9,10-EpOME).
What are the official names of this protein?
Epoxide hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Epoxide hydrolase family.
Protein: FTSH_PELPD
Sequence: MNQSFWRPLFAILLFMLVFHLTNIFFAQQGAQVAQISYSRLRAELAQDNIKKITLKGTAVTGEFRGKTRVSALVQGKEQQREFTGFSSVLPTIDDQTLVPELMARKVEVSALSTETPLLLNALIYVAPWVILIAIWWVGMRSMRSQGPSGMMGGFSRSGAKAYLAGDKMAVSFKDVAGMEDSKQELKEVVDYLRNPKQFARIGGKVPKGVLLVGPPGTGKTLLARAVAGEAGVAFFSISASQFIEMFVGVGASRVRDLFTNAKKAAPSIVFIDELDAVGRSRGAGFGGGHDEREQTLNQLLSEMDGFDQHEEVIVLAATNRPDVLDPALLRPGRFDRHVVIERPDWRDREKILQVHVRKITMNGRIDLGVIARGTPGMTGADLESLVNEAAILASRENAAAVTMEHLEKAKDKILMGSERRMIISLEEKRITAYHEAGHTLVARLLPGTDPIHKVTIIPHGMALGVTQQLPEDDRYHYPQSYLENRLVVAMGGRVAERLAFGEVSSGAQGDLKQVTSLAEKMVCQWGMSEKVGGMTFSRGEEHPFLGMKLAEEKTFSEAMAWRIDQEIAAFITRAEQRAGDLLSANRERLDLLAQALQDEETLDGSRVDEIIGSLNTAQAPPP
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: SYR_BORDL
Sequence: MIKTIKADLKNKIQKTIKELALSSNIKLDKINIVMQKPPKSEMGDLSILIFEFSKILKLSIPVITQEIIKQIGNEYKTKSMGPYLNIKFNRKEYIQNTIKKVNKEKENYGANNSLQNKKTIIEFSSPNTNKPLHVGHLRNDIIGESLSRILKASGSKVTKINLINDRGTHICKSMLAYKKFGNNITPEIAQKKGDHLIGDFYVKYNEYASQNSEIAENEIQQLLCQWEQGDEKTVQLWTKLNKWAIDGIKETYNTTNITFDKIYLESEIFKIGREVVINGLKEGLCYKREDGAICINIPTEKNNIDNQNFKQKVLLRANGTSIYLTQDLGNIVARKNEFDFDEMIYVVGSEQIHHFKTLFYVADKLGVTNENNLIHLSYGMVNLPEGKMKSREGNIIDADNLIHDLSQSTMLELKKRYENEQNLQKLALNISLGAIHYYLLKTAIHKDILFNKTESLSFTGNSGPYIQYVGARINSILDKYNNLNLANKNTNFDLLVNENEWEIIKIISEFEEYIIKASKDRNPSIIANYSYLLAKNFSTYYQDTKIIDKDNLELTHARIDLAKAVLQTIKNCMHLLNIPYIQKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_EHRCR
Sequence: MMKNNLVSNLRKSFIDFFAKNGHQVFPSSPLILKDDPSLLFTNAGMVQFKQMFTNPNNANVNTATSSQKCLRVGGKHNDLENVGYTNRHHTFFEMLGNFSFGSYFKEGAIEFAWNFVIKELSLSKDRLYFTVYHDDQEAFDLWKKISGVSDSRIIKITTSDNFWSMGNTGPCGPCSEIFYDYGDNVKGGLPGTPEEDGARFTEIWNLVFMQYDRKLDGELCVLPKKCIDTGMGLERIAAVMQGVHDNYDISLFKALIAASKEQSGNSTNELAHRVIADHVRSAAFLIAEGLTPGNEGRNYILRRIIRRAARYVYMLKYDDALMYKVFPTLIDEESCGYMADYYPELIHAKDLIMSILKIEEENFKDTLVRALPLLEKELMNLSSGDILSGDIVFKLYDTYGFPVDITLDIIKEKGVKFDEQGFYDNMNKQKERSKLNHSIKSDQQLKEEFWVDIKERCGSTKFVGYERYDTKATVLSIVCGGDKNVEIANVGDKVSILLDITPFYAESGGQKGDVGIFNVIVRQEKELFANDNIAEVIDTKKVLDTLYIHECIIKQGSLMVGDVIFAKIDCERRRNLCANHSATHLLHYVLKSEIDSSIMQKGSLVSDEKLRFDFSYGVALTKEQLTLIEDKMYSLISGNNPVISHVCDLKDAVAGGAVALFTEKYEEHGVRVVSIKDSKELCCGTHVKYTSEIGCFKIVSEASIACGIRRIEAVTGRYAIDYFRQQEKMLNSIAESVKVPVDNVLVQIDKLDKKNQELEQKLSDVYFDMINLQGVNTEKIGNVDFLYSNLSNIPVNVMRKFINKHLTADRIILFANVVGQNVVCVVGVGNSLHCKVKAVDFVKMIGTMVKSKGGGNAQLAQINGEYVKEIDIMSNVKSKLVDILSN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGZ_ECOSM
Sequence: MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKTTGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSDVDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISARLNQLHERWQEEKAGH
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_CAMJ8
Sequence: MKIYKLQTPVNAILENIAADKSISHRFAIFSLLTQEENKAQNYLLAQDTLNTLEIIKNLGAKIEQKDSCVKIIPPKEILSPNCILDCGNSGTAMRLMIGFLAGISGFFVLSGDKYLNNRPMRRISKPLTQIGARIYGRNEANLAPLCIEGQNLKAFNYKSEISSAQVKTAMILSAFRANNVCAFSEISLSRNHSENMLKAMKAPIRVSNDGLSLEISPLKKPLKAQNIIIPNDPSSAFYFALAAIILPKSQIILKNILLNPTRIEAYKILQKMGAKLEMTITQNDFETIGEIRVESSKLNGIEVKDNIAWLIDEAPALAIAFALAKGKSSLINAKELRVKESDRIAVMVENLKLCGVEARELDDGFEIEGGCELKSSKIKSYGDHRIAMSFAILGLLCGIEIDDSDCIKTSFPNFIEILSNLGARIDY
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_JANMA
Sequence: MQFPDRLIQHFDSALRVMSGVSVAGRPNPAAKVADGDLDSAQRRHSAGLMRVNHVGEVCAQALYQAQAQFARSPAIRQQLLLAGREEEDHLAWTAERLRELGSRPSLLNPLWYAGAFALGTVAATLGDARSLGFVVETERQVEAHLNQHLSSLPPQDAKSLAIVKQMSTDEAEHGAAAHALGAQTVPPLAQMGMQAMAKVMTSTAYYL
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RT83_ECOLX
Sequence: MSIDIETTLQKAYPDFDVLLKSRPATHYKVYKIPKRTIGYRIIAQPTPRVKAIQRDIIEILKQHTHIHDAATAYVDGKNILDNAKIHQSSVYLLKLDLVNFFNKITPELLFKALARQKVDISDTNKNLLKQFCFWNRTKRKNGALVLSVGAPSSPFISNIVMSSFDEEISSFCKENKISYSRYADDLTFSTNERDVLGLAHQKVKTTLIRFFGTRIIINNNKIVYSSKAHNRHVTGVTLTNNNKLSLGRERKRYITSLVFKFKEGKLSNVDINHLRGLIGFAYNIEPAFIERLEKKYGESTIKSIKKYSEGG
What is the function of this protein?
Reverse transcriptase (RT) component of antiviral defense system retron Ec83, composed of a non-coding RNA (ncRNA), this reverse transcriptase (RT), a probable ATPase and a putative HNH endonuclease.  Expression of retron Ec83 confers protection against bacteriophages T2, T4 and T6.  At multiplicity of infection (MOI) of 0. 02 cultures slow growth when infected with T4 but do not collapse, at MOI 2 cultures enter growth stasis (PubMed:33157039).  Responsible for synthesis of msDNA-Ec83 (a linear ssDNA with a 5'-terminal phosphate residue).  Unlike most known msDNAs the mature product from the original strain does not have an RNA component.  When the ncRNA plus RT are expressed in strain K12 / JM109 only linear DNA is seen in stationary phase cells, but logarithmic phase cells have both a linear and branched msDNA (a branched molecule with RNA linked by a 2',5'-phosphodiester bond to ssDNA, a 'classic' retron).  The branched msDNA is probably the precursor for the mature linear msDNA, the precursor is cleaved endonucleolytically by ExoVII (xseA-xseB) leaving the observed mature 5'-phosphate ssDNA terminus.  The retron transcript serves as primer (from a conserved internal G residue) and template for the reaction, and codes for the RT (PubMed:1282191, PubMed:26626352).  Overexpression of the ncRNA and RT, which leads to increased levels of msDNA, is mutagenic in vivo (PubMed:7885227).  This may be due to a mismatch in the msDNA stem which binds and sequesters MutS and/or MutL (Probable).
What are the official names of this protein?
Retron Ec83 reverse transcriptase, RT.
What is the protein family that this protein belongs to?
Belongs to the bacterial reverse transcriptase family.
Protein: FRDD_PROMH
Sequence: MNQNQLPKRSDEPIFWGLFGAGGMWSAIVSPAIIILLGILIPMGIAPEAFTYDRIMAFSQGFIGRIFLLLMIILPVWCALHRIHHTLHDFKVHVPASNWVFYGAAAIISVIAIIGVFTL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AI4_USTMA
Sequence: MVRWLYSTNAKDIGTLYLIFAVFAAMIGTAFSVLIRMELAAPGVQYLNGDHQLYNVIITAHAFVMIFFMVMPAMVGGFGNYLVPVMIGAPDMAFPRLNNISFWLLPPSLILLLASAFVEQGAGTGWTVYPPLSGLQSHSGGSVDLAIFSLHLSGISSMLGAMNFITTVLNMRNPGMTLHKLPLFVWAIFVTAILLLLSLPVLAGKFVPALNLAVCWELFSSVFSKIIDVKDDQQVTYESYNFIWNLNDCAPELSISHMSSLLFFGSYLAGLIEGDGTIVVPKQERSAKGKRNYPSVQIVFQLKDFPLCQIVQKLIGHGTISKKKQAAAYILTINNIQGLIELSNLINGKIRGPKYYQFVLLVEYLNKKCPNLNLKPAGFNKTPLGFDSWLSGFIEADGSFQVRTSLSSKYPRLSLSFELVQSRITHYGFTMFTIMQEIAIFLETNVNEIRSERKNPQYRLRTSSLKTNKNIRDYLVKYPLKGTKYLDFKDWCKVLSYFEQGTHMDNTARIVEIKSQMNQRRTVYNWDHLQ
What is the function of this protein?
Mitochondrial DNA endonuclease involved in intron homing.
What are the official names of this protein?
Probable intron-encoded endonuclease aI4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Multi-pass membrane protein.
Protein: CRM_DROSE
Sequence: MEELCKQPPPPPPLPPPPSSPSVAIEDPLPNGKGGGAVVVPSIAKLPEEELLGSVTMHNCPGTRASARVIQKMKQDQTRPMTPPPSEREPNKKEEKAAQKTPSQLKTGSGKTTWTNVERNCFFDALNEFGKDFEAVANCINAKLKRRNANSDYSFKTKDQVRQHYYQTYHKICKYVRFSEELKKPAQELYTLINYGEMRRKLQFLTEKHFMKLKQLVYQGQITVRCKGKNIRIKTPSCKALRRLNQLDDSLEDIRLPSKVEVLVTPANMEAFGRVQSLAQNPRGRIIVPLHKKLISFIKTFEYKWRSANQRLHEEKSAIFPSSLPSTATNNNNNNNETEPMQPSVASLDPSMCFQPRPGVAIHRPLLSITAYLSSISICLTAYEERMGFKVRSETLGNLAGMPVAASKRLRTESGSEKRSPETKKPKPSASPPLEKTLDDGPLEGNLMKMENSSGDELAEEIHEFLGDILEAMPHPQAVTIPALSTTTGDTTTVAVALETSHDPVLQAYPASADLSHAMVTSVIQTTCAAAPAPSTLVSGSLTAPSVARSKRKEAKEAAAAAQARNFKPLLSDDILKRIRKGWTQANAADITIGDLYVVFGQDSKLELEYYWCEVDSSTAMASSILTINTVAPSSSSVATQTGTSASNAIQTSASSNCYVSATSTSSTSLPYNPNDCDSVERVRAVTTSSVSNKLKHLLLVANLSERVRKRQCNCGHTCDRKRDLMTKAQQLAEATATGVVDGNFRTPMLPVRRPISNIDPVRQLSALTRQKINRQVLVQRRLLPPTSVGDRPYDLLSVRQLHSGLFEPIDRVDGTSSGGISSSGSKPDSSMGATAASQDQEPGDQRALDFLNDEATQASNRDMPNLDICVATSRTDVSGSLNEAVQDESTNQSFFHGSMSPMHLLRDSTSNARWLEDNINDFSLTSLLGHLDEIDATRDILDPSSSMSIISESSVDFRHKFQEIAALLQQQEKD
What is the function of this protein?
Polycomb group (Pc-G) genes are needed to maintain expression patterns of the homeotic selector genes of the Antennapedia (Antp-C) and Bithorax (Bx-C) complexes, and hence for the maintenance of segmental determination.  Can act as a modifier of position effect variegation (PEV) (By similarity).
What are the official names of this protein?
Protein cramped.
What is the protein family that this protein belongs to?
Belongs to the cramped family.
What are the subcellular locations of this protein?
Nucleus. Note=During S-phase in early embryogenesis.