PharMolix/UniProtQA huggingface dataset:
Protein: ILVC_BREBN
Sequence: MVKMYYEADVKQEVLRGKTIAIIGYGSQGHAQAQNLRDSGYKVVVGLRPGKSWDVAAKDGFEVLTVAEATKRADVVQILMPDERQAQVYRDEIAPNLKSGAALCFSHGFNIHYAQIVPPADVDVIMAAPKSPGHLVRRVYQEGFGVPGLIAIYQDATGNAKDLALAYSSGIGCTKAGVIETSFREETETDLFGEQAVLCGGASELVKAGFDTLVEAGYAPEIAYFECLHELKLIVDLMYEGGLARMRYSISDTAEYGDYSTGRRIITDETRKEMKKVLAEIQDGTFARNWILENQANRPGFTSRRRLESEHGIEVVGEQLRGMMSWINKDTKKEEVKIGQ
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PANB_DEHMB
Sequence: MRTTISQLKEMKQNKQKIAILTAYDYPTAQILDKAGIPAILVGDSLGMVVLGYDSTVSVTMEDMLHHLKAVVRGSQKALIIADMPFMTYHLSPEQALLNAGRFIQEGGAQAVKLEGGVNVADKVKRIVDCGIPVMGHIGLTPQSVNQLSGFKVQGKTLATALSLIEDAKALEKAGAFAIVLETMPAELAAIITAGISIPTIGIGAGEECDGQVQVISDMLGMFTDFIPKHTKRYADLNGIITKAVSEYAAEVTKGAFPTLKESFTLDKKVLEELKKCVL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_STAA3
Sequence: MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGGGVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVVKNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PURA_WOLPP
Sequence: MNNIVIVGLQWGDEGKGKIVDYLSENADVVVRFQGGNNAGHTIVIDDEVYKLNLLPSAVLRADKISIIGNGVALDSHALVSEIESLKVKGVDVNYNNLMVSESCPLILSVHKDKEKLFEDLNGNHKIGTTNKGIGPCYEDKVGRRAIRLCDLENTDELNQRVDALLSYHNAIRKGLNYQVVKKEEILKEIQEISEKILLYKKPVWKILNDFMKEGKKIIFEGAQGAFLDIDHGTYPFVTSSNTVASQAITGSGLSYNAQIIGVAKAYTTRVGNGPFPTEQNNEIGDSLFSIGKELGTVSNRRRRCGWFDAVLVRQAVQLSGVSSIVLTKLDILDSFDTIKIGTGYKYGGKMYDYLPASHSIQKELEPIYEEFPGWKEKTQGKRSVKELPANLMKYVRKIEELIGVPIHLISTSPNREDVIKLKNL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_FRAAA
Sequence: MRVVLASRNEAKLTELRRILAASGLSVELVALPDGEEVAETGTTFAENALIKARAAADQTGLPAVADDSGLAVDELSGMPGVRSARWSGRRDGTRVERDEANNALLLAQLDDVPPERRGAAFVCAAALVTPAGVERVTHGELRGVLLTEPRGQAGFGYDPLFLADGQTRTNAELTAAEKDAISHRGLAFRDLATLLREVLTS
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: DEF_ACIC5
Sequence: MMIRPIVKYPDPVLQQPAEPVTEFNEELRALVDDMFESMYEAKGIGLAAPQIGISKRLTVIDLSFKENPDEKIVLINPEIIHREGRQYEEEGCLSLPDIREKVVRAEKVTVRAQNLDGEWFEMDGEELLSRAFQHEIDHLDGVLFIFRISALKRDLVLRRIRKMQRAGEW
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: BTG3_MOUSE
Sequence: MKNEIAAVVFFFTRLVRKHDKLKKEAVERFAEKLTQILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACENSCILYSDLGLPKELTLWVDPCEVCCRYGEKNNAFIVASFENEDENKDEISKKVSRALDKVTSDYHSGSSSSDEDTSKEVDVKPSSVAATPSPVYQISELIFPPLPMWHPLPRKKPGMYRGSGHQTHYPPPVPFAYPNPGRKNKPFRPIPVTWVPPPGMHCDRNHWINPHMLAPH
What is the function of this protein?
Overexpression impairs serum-induced cell cycle progression from the G0/G1 to S phase.
What are the official names of this protein?
Protein BTG3, Abundant in neuroepithelium area protein, BTG family member 3, Protein Tob5.
What is the protein family that this protein belongs to?
Belongs to the BTG family.
Protein: LIPA_MYCS2
Sequence: MTVVPEGRKLLRLEVRNAQTPIERKPPWIKTRAKMGPEYTELKGLVRREGLHTVCEEAGCPNIFECWEDREATFLIGGEQCTRRCDFCQIDTGKPADLDRDEPRRVAESVQAMGLRYSTVTGVARDDLPDGGAWLYAETVRYIKRLNPNTGVELLIPDFNGNPEQLEEVFESRPEVLAHNVETVPRIFKRIRPAFRYDRSLAVITAARNFGLVTKSNLILGMGETIDEVRTALRDLHDAGCDIITITQYLRPSPRHHPVERWVHPDEFVELSAYAEGLGFAGVLAGPLVRSSYRAGKLYAQAARVRFADQPPVS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_NITWN
Sequence: MIIGIGSDLIDIRRVAKVIERHGDRFLNRVFTEIERAKAERRATNEKMVVSTYAKRFAAKEACAKALGTGIRQGVWWRDMGVVNLQAGQPSMMLTGGALKRLQLLTPPGLEVRIDVSLTDDWPLAQAFVIISAAAAGKL
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_SORC5
Sequence: MANHASADKRNRQRITRTARNRAIKSELRTTVKKARTALKGVPQESAAPVTAAVSALDRAASKGTIPAKRASRVKSRLALALHKASVAAKTAAS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: A20A1_HUMAN
Sequence: MKLFGFGSRRGQTAQGSIDHVYTGSGYRIRDSELQKIHRAAVKGDAAEVERCLARRSGDLDALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTPLIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLSHGAHIEALDKDNNTPLLFAIICKKEKMVEFLLKKKASSHAVDRLRRSALMLAVYYDSPGIVNILLKQNIDVFAQDMCGRDAEDYAISHHLTKIQQQILEHKKKILKKEKSDVGSSDESAVSIFHELRVDSLPASDDKDLNVATKQCVPEKVSEPLPGSSHEKGNRIVNGQGEGPPAKHPSLKPSTEVEDPAVKGAVQRKNVQTLRAEQALPVASEEEQERHERSEKKQPQVKEGNNTNKSEKIQLSENICDSTSSAAAGRLTQQRKIGKTYPQQFPKKLKEEHDRCTLKQENEEKTNVNMLYKKNREELERKEKQYKKEVEAKQLEPTVQSLEMKSKTARNTPNWDFHNHEEMKGLMDENCILKADIAILRQEICTMKNDNLEKENKYLKDIKIVKETNAALEKYIKLNEEMITETAFRYQQELNDLKAENTRLNAELLKEKESKKRLEADIESYQSRLAAAISKHSESVKTERNLKLALERTRDVSVQVEMSSAISKVKAENEFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNDLSQTQQQTQEMKEMYQNAEAKVNNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFIESGKKDLVLEEKSKKLMNECDHLKESLFQYEREKTEGVVSIKEDKYFQTSRKTI
What are the official names of this protein?
Ankyrin repeat domain-containing protein 20A1.
Protein: LIPB_THEVB
Sequence: MKNALGWHCALGIIPYRDAWRWQQQLVAERRQNLAAPDVLLTLEHPAIYTLGQGATTAHIHFDPVATGIEVLRIERGGDVTYHCPGQLVAYPILNLRRHCCDLHWYLHQLEEVIIQTLRHYGIKGERVAGLTGVWVEGYKVAAIGIKVTRWISFHGIALNVVNDLKGFGRIVPCGIGDRPVGNLRQFCADIQLEDVRQQFVAAFSRVFGLEFAPKALADLLIPTSS
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_BRUSI
Sequence: MTETTPKTAPWTVQKRTAVLVLADGTVIEGKGLGATGAVEAEVVFNTALTGYEEILTDPSYAGQIVTFTFPHIGNVGANAEDIEDLTPANRHGAVGAIFKADITAPSNFRAAEDLDSWLKHRGIIALAGIDTRALTALIRERGAQNAVIAHDPNGNFDLDALKARAANWCGLENLDLAKDVTIGQSLVWKELPWTLQDGYGEQDAPQYHVVALDFGVKRNILRLLTGLGAKVTVLPATATAEDVLAHNPDGVFLSNGPGDPAATGEYAVPTIGKLVETGIPLFGICLGHQMLALALGGRTEKMHQGHHGANHPVKDYTTGKVEIVSMNHGFAVDSDSLPENVEETHVSLFDGTNCGLRVVGKPVFSVQHHPEASPGPQDSHYLFRRFINLIRERKGQAPLPESEQAA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: HSCA_RICAH
Sequence: MQIIEIREPEQTDFKQKQQIAVGIDFGTTNSLIAIATDRKVKVIKSIDDKEITPTTIDFTSNNFTIGNNKGLRSIKRLFGKTLKEILNTPALFSLVKDYLDVNSNELKLNFANRRIRICEIAAEVFIYLKNQAEEQLKTHITKAVITVPAHFNDAARGEVMLAAKIAGFEVLRLIAEPTAAAYAYGLNNNQKGCYLVYDLGGGTFDVSILNIQEGIFQVIATSGDNMLGGDDIDVVITQYLCNKFDLPNSIDTLQLAKKAKETLTYKDSFNNDNISINRQILEQLILPLVEYTINIAQECLAQAGNPNIDGVILVGGVTRIPLIKDELYKAFKVDILSDIDPDKAVVWGAALQADNLIAPHTNSLLIDVVPLSLGMELYGGIVEKIIMRNTPIPIAVVKEFTTYADNQTGIQFHILQGEREMAVDCRSLARFELKGLPPMKAGNIRAEVTFAIDADGILSVSAYEKISNTSHTIEVKPNHGIDNTEIDIMLENAYKNAQIDYTTRLLQEAIIEAEALISSIEGAMAELTTLLSESEISVINSLLDNIKAAAKARDRILINNSIKEFKSKINKSMDTNLNIIINGVLKGKNINQIQ
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PPNP_SALSV
Sequence: MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEEMTVVSGALKVLLPGTVEWKVYTAGEVFNVPGHSEFHLQVAEPTSYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: PSBL_SCIVE
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LY66C_HUMAN
Sequence: MKALMLLTLSVLLCWVSADIRCHSCYKVPVLGCVDRQSCRLEPGQQCLTTHAYLGKMWVFSNLRCGTPEEPCQEAFNQTNRKLGLTYNTTCCNKDNCNSAGPRPTPALGLVFLTSLAGLGLWLLH
What are the official names of this protein?
Lymphocyte antigen 6 complex locus protein G6c.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: V1R90_RAT
Sequence: MRRISTLYGVVDKQAIFFSEVVIGISFNSILFLFHIFQFLLERRLRITDLIISLLALIHLGMLTVMGFRAVDIFASQNVWNDIKCKSLAHLHRLLRGLSLCATCLLSIFQAITLSPRSSCLAKFKYKSTQHSLCSLLVLWAFYMSCGTHYSFTIVADYNFSSRSLIFVTESCIILPMDYITRHLFFILGIFRDVSFIGLMALSSGYMVALLCRHRKQAQHLHRTSLSPKASPEQRATRTILLLMSFFVLMYCLDCTISASRLMHNGEPIHHSIQMMVSNSYATLSPLLLIVTENRISRFLKSLLGRTVDA
What is the function of this protein?
Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior.
What are the official names of this protein?
Vomeronasal type-1 receptor 90, Pheromone receptor VN6, Vomeronasal receptor 6, Vomeronasal type-1 receptor A16.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PKS2_METAQ
Sequence: MPKLSQQAPLVSSGSGVIASQTFADLIRAALRDILLHRLDLPALVGHLTGIFGLSSNESFVITPVSTNVATGLVAATAKAVGKTGSVDNEIMEAVALAGSRGTSARTHDSKIAIIGMSGRFPEAADLDSFWSLLVQGVDAYRPVAPDRFDAHAHYDETGRRKNTSKVLGGCWINQPGLFDPKFFSISPKEAEQSDPAQRLALQTAYEALEMAGMVPDRTQSTQRERVGVFYGMFTQGGIRAFTPGRINYHFKFSGPSITVDTACSSSLAAIHVACNSLWRGDCDTAVAGGVNVLTNPDIFAGLDRGHFLSTTGNCKTFDDDADGYCRADGVGTVILKRLEDAIMDKDPILAVLNSAYTNHSAEAVSITRPHAGAQELIFSKLLRETGIHPHDVSYIEMHGTGTQAGDATEMSSVLRTFAPDTGRLSNQTLHLGSAKSNVGHGESASGVTSLIKVLLMMKHNTIPPHCGIKGRINHRFPTDLRERNVFIASQPVAWDKPHSGSGKRRVFINNFSAAGGNSALLLEDAPTRQHPETKDPRSTHIVAVSAKSSTALVNNLKRLKVFVQDNIHNLDLLAKLSYTTTARRIHYPFRAAITASSSDQLLQGIESILLRDESTKPATSQKNIGFVFSGQGAQYAGMGRHLFQNNETFRTQVLACNQICLSQGFPSILDIFNQGVEMNNLEPLVVQLGTTCLQMSLVSFWKSLGVTPDFCIGHSLGEYAALQAAGVLSVSDTIYLTGIRARLLQKKCSAGSHAMLAVRAPLAQVHGFFNPSIHEVTCLNSPHDVAIGGLVADIEDLERELAENNIEAVKVSVPFAFHSTQVEPILDEFCAAAESVQFQTQRIPVISTLLGEVVLPEAKAVFGPEYLKRHCREPVNFTAAAQAGKDANIINSASVFIEIGPHTVCSALLKSNIGPNAVTLPSLHRKDDGWKVLADTLAGLYHSGLRINWDEFHRDFESCQEVLQLPSYCWDNKNYWIQYVHNWTLTKGDPPATTAQTPALELPENSTSSVQKVIQQTDGPGPFVTIVVQSDFGSPRLAEVAEGHKVNGEMLCTSSLYAEIGMTLGRQLLEKYRPDLQGYSTEIEDMSVDKPLILKEKNKETLFRAEVVHDKSTLTAAMSIYSVDSAGKKTVDHAHCILRFADPKSWLDEWERTYYSIERSVRWLEARVEQGTDSLLSKGIVYKLFSSLVDYSPSFKGLQEVILNSSDREATAKVRLQAEKEDFDYNPMWIDSFGQLTGFLMNGHDFTEKDQVFINHGWRSMRCAKQFRKDAVYRTYICMQNVDKTKYCGDLYIIEDGVIIAVFGGMTVLPPRRGADAIHTPNPVAAAPAGLVASTKAHVRRPLDIPTRAQRQASSPQSGAIHRILVILAEEVGLSLETLTDDLVFADYGVDSLLSLTITGRIREELDLDVDSSTFTNCSTLGELRLFLAADQKLDDAVACESSNGQHTPQTSDKGSGTLTAQKPDHDTDSEMTLNRVCAIIAEEVGISVEELSSSQDFQELGIDSLSALTILSRVREELQLDLESDFFDTHPSFYSLQKTLRGTEGASNRTLEPNGAIPSRHDLKSDLGNIEWQSGQNIVASAPHATSILVSGSPSTARMILVLFPDGSGSAASYGALAPKIRKDIAVYALNCPWRTNGEEILRLGVSLDQMVAKHLIEVRRILDNHQQSRLNGSIDLALGGWSAGGILAIEGVRQLRQTGIVVQKLVLLDAPNPIGLQNPPPRMFHFLDELGILGAGTGKAPTWVLQHFDAMVNLLKSYRPRPLSAESAPKSLIVYAKDGVCKDPKGPQMDTKPDDAREMLWLLYDRVDFSAEGWKSLVGQQNLVVGVVEDVNHFSMMNPGPKIIEMSNLIGDFLLGLN
What is the function of this protein?
Polyketide synthase; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster (Probable).  The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified (Probable).
What are the official names of this protein?
Polyketide synthase 2.
Protein: ACT1_HELER
Sequence: MCDDDVAALVIDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVFDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMSTAASSSSLEKSYELPDGQVITIGNERFRAPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMFPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin CyI, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LDH_PLAFD
Sequence: MAPKAKIVLVGSGMIGGVMATLIVQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVTNPVDVMVQLLHQHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNAHIVGAHGNKMVLLKRYITVGGIPLQEFINNKLISDAELEAIFDRTVNTALEIVNLHASPYVAPAAAIIEMAESYLKDLKKVLICSTLLEGQYGHSDIFGGTPVVLGANGVEQVIELQLNSEEKAKFDEAIAETKRMKALA
What are the official names of this protein?
L-lactate dehydrogenase, LDH-P.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
Protein: HEM1_AQUAE
Sequence: MGEIFVAGVNFKVAPVEVREKLACSLEETKKVLPILKRETPLEEVMLLSTCNRVEVYAYNFVENSEDLINKLLEIKRLNPSFKRYFFVKRGEEAVYHIFKVASSLDSMVIGEPQIVAQFKEAYRVAKEAGTVGKILNRVYEKALRASKRVRTETGISRSAVSVSYAAVELAKKIFGDLKEAKVLLIGAGEMGELAANYLRRFGAKLHITNRTYERALKLVKELSGNVLRFEELKEYLPLMDIVIVSTGAKDYILKREDFERSVRERHYEPQFVIDIAVPRNVDPEAGNVEGVFLYDIDDLKQVVEENLKERIKEAQRGEIILWDEVKKFMNWYESLKAEPYILELKASVEGKEVSPYIKKLVHRAIKEIKRNPEVADIILRIFKEVEKNEPRRKELSNVYNGTHGA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SFAS_CHLMO
Sequence: MSISPGRSFSPMRASGLTGITSAGPTAKLEHVSERFASLWTDLEHEKQNRKLAESSRFQLFTEAVSRLEKGLEAEVKRRAESDKQLQSHFEGEIRALAERSAAQHVDMQNSLKQAVDSLSNRLQDLHSLVREEREQRRNDIEHLATSLVGKVNECVQALDEERNSRLQDQSLSLKRFGEDLITIQQRVDQEKLVRDAELSGLRSEVHEALGNRNLADEQFRNMTLDELTALKGALALEREERIAEDDEIVQAINDYTKALQEGLKLVST
What is the function of this protein?
Major component of the striated microtubule-associated fibers (SMAFs; system-I-fibers).
What are the official names of this protein?
SF-assemblin.
What is the protein family that this protein belongs to?
Belongs to the SF-assemblin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DDL_LIMRD
Sequence: MTQKLHIALLFGGNSSEHDVSKRSAHNIYDALDKEKYDVSLFMFTKDGILLGNEDSQKIFDGEPEDQVVAEAYQKMDMSSPLAPIMALNEQKEIDFFFPVIHGNLGEDGTIQGLFKLLNKPYVGSNIAASAMSFDKDLTKKIISQAGIRNTPYVVVTPENQADYSWGRIEEKLGNLTFVKPAKQGSSVGIHRVTNAEEYEKALDDAFKYDYKILVEQGIANPQEIEISILGNEHPIASKLGAVRVPKDDPFYDYENKFVDASGVVFELPVKLPQYLVDEITDMALKAYKALGMKGMARIDFLVDSNNVPYLGEPNTLPGFTNISLYPQMWEVSGISYSDLIDRLIQLGLQEFERNSKIKYDFRKLGTERVGQKKYNED
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_ACAM1
Sequence: MSLDSRRYHITTYGCQMNKADSERMAGVLENMGYQWSENPDDANLILCNTCTIRDNAEHKVYSYLGRQAKRKHAQPDLTLVVAGCVAQQEGDALLRRVPELDLVMGPQHANRLQDLLEQVASGQQVLATEPIHIVEDITKPRRDSAVTAWVNVIYGCNERCTYCVVPNVRGVEQSRTPEAIRAEMVQLGEQGFKEVTLLGQNIDAYGRDLPGTTSEGRHQHTLTDLLYFVHDVPGIERIRFATSHPRYFTERLIQACYELPKVCEHFHIPFQSGDNDVLKAMSRGYTHEKYRRIIDNIRAIMPDASISADAIVGFPGETEEQFMNTMQLVEDIEFDLLNTAAYSPRPGTPAALWDNQLSEEVKADRLQRLNRLVGVCAELRSQRYANRIEEVLVEDQNPKDPTQVMGRTRGNRLTFFPGNIEQLRGEIIAVKVTEVRSFSLTGEPLSSVATAVR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y453_METLZ
Sequence: MIREKFAYRETITTILADDTSHVEAAKGGMIAARTGVEEYLLTDPFFQMSYSPVSAPADAPESVRCMAAASFEADVGPMAAVAATIGWAGVKAMQNRGAAFGLIDNGGDIVLFSNRELRVGIYAGPAPSSGKFAFLITPQTEILGICTSSATVGPSVSFGIADSVTCFSHDPAKADAWATGLCNILTPENFDKVMKKVEESSVFAVYAVIGDWIGRWGDLPEIVPAHVSYDLITKG
What are the official names of this protein?
UPF0280 protein Mlab_0453.
What is the protein family that this protein belongs to?
Belongs to the UPF0280 family.
Protein: NIKR_SULIN
Sequence: MSAEKISISLPKELYRELEDFITRKGIPDRSKIFQIALRNYLDENREGTEIIYGIINLVYDHEEASEALTEIQHEYKDNIISTLHLHVNERLCIEAIAVKGEKSKLVELNNRLGQIRGILKARLLISFPYEKT
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: RS15_YEAST
Sequence: MSQAVNAKKRVFKTHSYRGVDLEKLLEMSTEDFVKLAPARVRRRFARGMTSKPAGFMKKLRAAKLAAPENEKPAPVRTHMRNMIIVPEMIGSVVGIYNGKAFNQVEIRPEMLGHYLGEFSITYTPVRHGRAGATTSRFIPLK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  uS19 is involved in the nuclear export of the small ribosomal subunit precursor.  Has a role in the late stage of the assembly of pre-40S particles within the nucleus and controls their export to the cytoplasm (PubMed:15167894).
What are the official names of this protein?
40S ribosomal protein S15, RIG protein, RP52, S21, Small ribosomal subunit protein uS19, YS21.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPT_SULAC
Sequence: MLVSLLGILLSVIVGFVVTLISTKWVIGLCKKRGFTGKDINKLTKDDVPVLGGIGIVAGFVAGSFTFLLTSYNLSPGIENVVVSILLSSLIIGFLGLLDDIFNISQATRAFLPIFASIPLILYSVGHTIISIPFLGKVNFGILFYIIILPATLTITANAFNMLEGLNGLGAGMGLIMALALAYIGLKSGGTSFYAGIVSIILASVLFGFLIFNFYPAKTFPGNIGTYFIGSVIGSIGISGYMYTALFFLYLPYVIEFVLKAKTRFKGVSFGKIDDQGYLHWDSKPNSLTHIVMRIGKFKEYHIVLIIWGIEILFAILAVVFQTVTITI
What are the official names of this protein?
Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-P transferase, G1PT, GPT, N-acetylglucosamine-1-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YFU3_GEOSE
Sequence: MWNVTIKAAPPYDFDRVLERLSLDPLNKVDVHKRTVLVPLYSEKEEPFVAVVKAIGSKENPIFEISGEQDEQKERAIHELTRIFQWKNS
What are the official names of this protein?
Uncharacterized protein in fumA 3'region, ORF3.