PharMolix/UniProtQA huggingface dataset:
Protein: FYV7_YEAST
Sequence: MGTAKQNQNRKKFTREYKVKEIQRSITKKTRLRKEYLKALKDEGYAVPEKEPKTVAKESVRKIKEARAIEGKKKLDEKKEIKKQRKRMQKDELNKQRNEQLERIRVSKEKFQRREDRKKKLTQRTRTGQPLMGPKIEDLLDKIKTDDTYTS
What is the function of this protein?
Involved in the processing of the 20S pre-rRNA.  Required for survival upon K1 Killer toxin exposure.
What are the official names of this protein?
rRNA-processing protein FYV7, Function required for yeast viability protein 7.
What is the protein family that this protein belongs to?
Belongs to the FYV7 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PYRB_RUTMC
Sequence: MKKDLISNHIQLDDSGKLIHLLGLEGLSKQYLIHILDTADSLIDVSGNLKKSKALDDIFVANLFFEPSTRTRNTFEIAAMRSSANVINVDLANSALKKNEDLLNTMRTLKAMQIDMFVIRHKQNGLPHHVVQHLKDVSILNAGDGINAHPTQALLDMLSIRQHKKTFENLSVAIVGDITHSRVAHSDIQALKTLGTTDIRLIAPKVLQYNLAPCSVVKHFDDIEPGLKNCDVVIVLRLQKERMIEADIPNEQEYFDNFGLTPKRLALAKPDAIVMHPGPTNRGVEIDSNVADGNQSIILQQVTNGIAVRMAVMQILVNKS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: HSP1_SAISC
Sequence: MARYRCCRSRSRSRCYRRRRRCRTRRRRCCRRRRARRCCRRRYKLRCRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RBFA_BARBK
Sequence: MKHADLSQRQLRVGEQVRHALAHMLQRGILLDDALKDVVFSVSEVRMSPDLKIATCFVSFLNTVDDISRATLIKVLNKHSRFIRGEISSSLRQMKYMPELRFRLDNSFDNFSKIDALLRLPEVARDLHHHKPED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPA9_SHIF2
Sequence: MLPINNNFSLPQNSFYNTISGTYADYFSAWDKWEKQALPGEERDEAVSRLKECLINNSDELRLDRLNLSSLPDNLPAQITLLNVSYNQLTNLPELPVTLKKLYSASNKLSELPVLPPALESLQVQHNELENLPALPDSLLTMNISYNEIVSLPSLPQALKNLRATRNFLTELPAFSEGNNPVVREYFFDRNQISHIPESILNLRNECSIHISDNPLSSHALQALQRLTSSPDYHGPRIYFSMSDGQQNTLHRPLADAVTAWFPENKQSDVSQIWHAFEHEEHANTFSAFLDRLSDTVSARNTSGFREQVAAWLEKLSASAELRQQSFAVAADATESCEDRVALTWNNLRKTLLVHQASEGLFDNDTGALLSLGREMFRLEILEDIARDKVRTLHFVDEIEVYLAFQTMLAEKLQLSTAVKEMRFYGVSGVTANDLRTAEAMVRSREENEFTDWFSLWGPWHAVLKRTEADRWAQAEEQKYEMLENEYPQRVADRLKASGLSGDADAEREAGAQVMRETEQQIYRQLTDEVLALRLSENGSQLHHS
What is the function of this protein?
Effector E3 ubiquitin ligase that interferes with host's ubiquitination pathway and modulates the acute inflammatory responses, thus facilitating bacterial colonization within the host cell.  Interacts with IKBKG (NEMO) and TNIP1 (ABIN-1), a ubiquitin-binding adapter protein, which results in TNIP1-dependent 'Lys-27'-linked polyubiquitination of IKBKG.  Consequently, polyubiquitinated IKBKG undergoes proteasome-dependent degradation, which perturbs NF-kappa-B activation during bacterial infection.  Mediates polyubiquitination of host U2AF1, leading to its proteasomal degradation.  Catalyzes 'Lys-48'-linked polyubiquitination and subsequent degradation of a subset of host guanylate-binding proteins (GBP1, GBP2, GBP4 and GBP6), thereby suppressing host cell defense.  In contrast, host GBP3 and GBP7 are not ubiquitinated by IpaH9. 8.  Uses UBE2D2 (UBCH5B) as an E2 ubiquitin-conjugating enzyme.
What are the official names of this protein?
E3 ubiquitin-protein ligase ipaH9.8, Invasion plasmid antigen ipaH9.8.
What is the protein family that this protein belongs to?
Belongs to the LRR-containing bacterial E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Note=Secreted via Mxi-Spa type III secretion system (TTSS), and delivered into the host cytoplasm. Transported into the host nucleus (By similarity).
Protein: FTHS_FUSNN
Sequence: MTDIQIAQAAKKENIVEIAKKLGLTEDDIEQYGKYKAKVNLDVLQKNKRPNGKLILVTAITPTPAGEGKSTVTIGLTQALNKMGKLSAAAIREPSLGPVFGMKGGAAGGGYAQVVPMEDINLHFTGDMHAIGIAHNLISACIDNHINSGNALGIDVTKITWKRVVDMNDRALRNIVIGLGGKANGYPRQDSFQITVGSEIMAILCLSNSITELKEKIKNIVIGTSVTGKLIKVGDFHIEGAVAALLKDAIKPNLVQTLENTPVFIHGGPFANIAHGCNSILATKMALKLTDYVVTEAGFAADLGAEKFIDIKCRLGGLKPDCAVIVATVRALEHHGKGDLKAGLENLDKHIDNIKNKYKLPLVVAINKFITDTDEQINMIEKFCNERGAEVSLCEVWAKGGEGGIDLAEKVLKAIDNNKTEFDYFYDINLTIKEKIEKICKEIYGADGVIFAPATKKVFDVIEAEGLNKLPVCMSKTQKSISDNPALLGKPTGFKVTINDLRLAVGAGFVIAMAGDIIDMPGLPKKPSAEVIDIDENGVISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: LACA_LACLL
Sequence: MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTLAVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMITVGAEIVGDELAKNIAKAFVNGKYDGGRHQVRVDMLNKMC
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: GYRA_CHLMU
Sequence: MLNKEEIIVPKNLEEEMKESYLRYSMSVIISRALPDVRDGLKPSQRRILYAMKQLNLTPGAKHRKCAKICGDTSGDYHPHGEAVIYPTLVRMAQDWAMRYPLVDGQGNFGSIDGDPAAAMRYTEARLTHSSIFLLEDLDKDTVDMVPNYDETKYEPVVFPSKFPNLLCNGSSGIAVGMATNIPPHNLGELIEATLLVLANPQTSIEEILEVMPGPDFPTGGIICGTEGIRSTYYTGRGKLRLRARIHVEENSDKQRENIILTEMPYNVNKSRLVEQIAELINEKTLTGISDVRDESDKDGIRVVLELKKGESSEVIINRLYKFTDVQVTFGANMLALDKNLPRTMSIHRMISAWIRHRMDVIRRRTRYELNKAETRAHILEGFLKALSCMDEVVKTIRESSNKEHAKQQLVELFGFSEAQSLAILELRLYQLTGLEIDKVQKEYNELLEKIAYYRRVLAEEELVKDIIREELQELHKVHKTPRRTTIEMDAGDVRDIEDIIADESVIITISGDDYVKRMPVKVFREQKRGGQGVTGFDMKKGSDFLKAVYSASTKDYLLIFTNMGQCYWLKVWQLPEGERRAKGKPIINFLEGIRPGEQVAAVLNVKRFEQGEYLLLATKKGVVKKVSLDAFGSPRKKGIRALEIDDGDELIAARHIVNDEEKVMLFTRLGMAVRFPHDKVRPMGRAARGVRGVSLKNEEDFVVSCQVVTDDQSVLVVCDNGFGKRSLVCDFRETNRGSVGVRSILINQRNGDVLGAISVTDFDSILLMSAQGQAIRINMQDVRVMGRATQGVRLVNLREGDTLVAMEKLSVNTESGETEESVSIQVGHAVEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POTA_LISIN
Sequence: MIVTETIIRFENVTKQFDNDPPVLDNVSFEIEKGKFYTLLGPSGCGKTTILRLIAGFLEASEGQIYLGDKVINQIPANKRPVNTVFQDYALFPHLNVYENVAFGLRIKKLKKDAIDKKVQEALRFVNLKGYEKREISEMSGGQRQRVAIARAIVNEPEVILLDEPLSALDLKLRTEMQYELRDLQKRLGITFIFVTHDQEEALAMSDEIFVLNKGEIQQSGTPIDIYDEPINKFVADFIGESNIVNGKMIQDFEVEFVERRFECVDQGFRPNEVVEVVIRPEDLEITSAEKGKLQVTVDWMLFRGVHYEVGCIDIDGNEWLVHTTRKVRVGDKIGLAFEPEAIHVMRLGETEEEFDKRLDSYDEVQ
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YIMB_BPPH1
Sequence: MQYAFSFSFWADIEYPSFACSSVETLTYIPTFFGVFSSIKFMIIYPPFLETYVLFSG
What are the official names of this protein?
Uncharacterized immunity region protein 11.
Protein: PIGX_MOUSE
Sequence: MAAGAVAWLLLWAAWLVGRLAADFSDAPFSAGKGVRATCSEIILRQEFLKDGFHRDLLIKVKFGESIEDLQTCRLLIKHYIPPGLFVDPYELASLRERNLTEAVMLSESFNIEAPNYLSNESAVLIYARQDAQCIDCFQAFLPVHYRYHRPHKKDGDTLIVVNNPDLLMYCDQEFPILKCWAQSEVAAPCALKSEEICQWKSMQYKSILKNLTVQVPVGLTIHTSLVCSVTLLITILCSTLILLAVFKYGHFSL
What is the function of this protein?
Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.  Probably acts by stabilizing the mannosyltransferase PIGM (By similarity).
What are the official names of this protein?
Phosphatidylinositol-glycan biosynthesis class X protein, PIG-X.
What is the protein family that this protein belongs to?
Belongs to the PIGX family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: IRC22_LODEL
Sequence: MKVFTLLAAAAASIATVVGYETAEKQFVDILIEYQIVQTPEVTKNDVAQWTNGDEVTLKYNIVNNEEKEVTVIGVTGQFTNPVTNEIVTNLTQGRVGPLSIPPGQSASFEQNIGIDVIPNNYELIPQVFFAHDELIKVIPCRGQLATVADKSISFFDPRLIFLELVLLASFAGIAYLAYQIWGKKYIQGTAPVKVKKTTAVTSVPAGTGVSTTTTGASGYDVNWIPEGHLKQKKTKKVA
What is the function of this protein?
Is probably involved in a pathway contributing to genomic integrity.
What are the official names of this protein?
Increased recombination centers protein 22.
What is the protein family that this protein belongs to?
Belongs to the IRC22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: Y2479_PHOLL
Sequence: MPITANTLYRDSFNFFKNQLLSTLTLAVLAALVTTLLGHLFIPDSEQMKLLTEAEFTFATSGKAGIQELVSQMTPEQQSMIMRAGIGTIFSSMIGSVLLVGGVLTLVAAVSAGNRISSLQAIGLSASQLPKLFLLLLICTLLIQFGLMLMLVPGIILSIALALSPVIMTAERRGVFASMKISWKLAFANIRLLVPAILLWLTARLLLVFIIDRLTFIHSEMAGIILGVFNNLISAILLIYLYRLYMLIASPQQKSI
What are the official names of this protein?
UPF0259 membrane protein plu2479.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: F168A_HUMAN
Sequence: MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYATLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAPPPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAIYPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYVPPHW
What is the function of this protein?
In cancer context, protects cells from induced-DNA damage and apoptosis.  Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation.  Decreases POLB ubiquitation and stabilizes its protein levels.
What are the official names of this protein?
Protein FAM168A, Tongue cancer chemotherapy resistance-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the FAM168 family.
Protein: YR260_MIMIV
Sequence: MNKESTDLYEILGLTPSASEEDIKKAYRKLAIKYHPDKNKGNPEAEEMFKKINHANSILSNSEKRRVYDQYGEEAVNNGLNEDSFDPMSMFMRMHQPGNKKLRAQMRHQISLQDYFTKKTVKVTITVDSKCDDCDATGFSDKQKHVCKVCRGKGIVVNEIRNGPFIQQIQQHCHGCQGKKYDTTAKDLHCPSCKGAGINKSEEETEVNVPFDILRNPKVILEGKGPWVDGKNIDLEIVFILAFSDGFELTDNHKLIYTMEINFPETLCGFRRIIDHPSGDSLLIVANPGFVINPHYIYLLERKGLNNDTLYLKFKINYSKLIHIPKKKVFNFENLEIALGTRYVPDVSDDIGTEPENVFNLSTLRQINTDPSDESQDRDSEESYGGHGRPEGVGCAQQ
What are the official names of this protein?
DnaJ-like protein R260.
Protein: ALLA_BURM7
Sequence: MKTLSIEPLTRAAFAPFGDVIETQGAKQIPINLGTTMRFHDLAKIDVADEGGRPLVNLFRGQPRTLPFEVTMLERHPLGSQAFVPLTDRPYIVVVAPAGDLDASKIRAFVTSGWQGVNYAKGVWHHPLIALGEVSDFIVVDRGGDGRNLNEQNLPESLWLTDDALLAVGA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the utilization of allantoin as nitrogen source.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: RNZ_PYRAR
Sequence: MPLLKLVFLGTGGAVPRADRMLPAIYLEDWLGHRILLDAGEGVQYRLFQIGVAPSSLTLVAVTHMHEDHVLGLPGLVITAKFLGGKVKLLGPRSAHGILSRLGVDVADGYDGGRLRVRCVEVCHTVDACGWLLEWDVGYKLDLKKVEGLPKWALTKLIRGEEVEVGGRVIRPEEVADPAHKRYRRLLYTGDTGPCPRMLKTVGEVDVLIHEATFADDVDPNKAHEEGHSTVADAVEAAKALRAGVLVLTHISARYTDKARHRQLAGRVPPPPHVYVPDDFDTLLVQL
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ATG16_YEAS7
Sequence: MGNFIITERKKAKEERSNPQTDSMDDLLIRRLTDRNDKEAHLNELFQDNSGAIGGNIVSHDDALLNTLAILQKELKSKEQEIRRLKEVIALKNKNTERLNDELISGTIENNVLQQKLSDLKKEHSQLVARWLKKTEKETEAMNSEIDGTK
What is the function of this protein?
Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy.  The ATG5-ATG12/ATG16 complex is required for efficient promotion of ATG8-conjugation to phosphatidylethanolamine and ATG8 localization to the pre-autophagosomal structure (PAS).  Recruits also ATG3 to the PAS.  Involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity).
What are the official names of this protein?
Autophagy-related protein 16, Cytoplasm to vacuole targeting protein 11, SAP18 homolog.
What is the protein family that this protein belongs to?
Belongs to the ATG16 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: GATB_AJEDR
Sequence: MIRQCLSRRGAYSRYRLAARGVELAEPFHHQSSRPQGRRNWSSSPRCSLDIRTDTPRSRSEYVPLRKQLKEEAKAKRAAKRKGSAPPAKHDDWELTVGIEIHAQLDTDAKLFSRASAAIDDIPNSNVALFDIALPGSQPLFQPSTLIPALRAALAMNCDIQRVSRFDRKHYFYQDQPAGYQITQYYEPYAKNGSIWLQEHDGIAREDGEGVQIGIKQIQMEQDTAKSQELPSSTYLLDFNRVSRPLIEIITLPQIHSPATAAACVRKIQAILQSVGAVTTGMEMGGLRADVNVSVRKRSEEAGDHEYHGIVGLGQRTEIKNLSSFKAVEDAIIAERDRQIAVLEAGGTIEGETRGWTLGSTETRKLRGKEGEVDYRYMPDPDLGPVVIGEDVICDLQMKMPLLPDALFQMLVRNPKYKLSTADAKTMIELDDGQRLEYYQDVVDILIGLQTDLSADFSGGKAVGNWVLHELGGLLTKSSLPWDSGRVPAQSLAEIIDLLSRKEITSSSAKSLLAMVFDGDKRSVAQIVEDENLRFQSLSRGEYIALAEEVMRQNPKMVSEIREKGQLGKIGWFVGQIKRIGDANRVEAQKAEEILRELILKKNS
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LAP1_SCLS1
Sequence: MKFTNLSLLALSASLASARFVEQHETDQVILNSNAVTDERYLIETAPGKQQWVTEEEKWELRRNGQNFMDITETPELGTLRTSSVKVKFPSKPTLQKDLKPLLEDLSKSKMHKNLETFTSFHTRYYKSDYGRQSSEWLLEQVQTLIKDAGADKYGAHARHFKHSWGQNSIIATIPGQKNSTVVIGAHQDSINLFLPSILSAPGADDDGSGTVTILEALRVLLTSKDIIKGKGENTIEFHWYSAEEGGLLGSQAIFSEYEKTGRDVKAMLQQDMTGYTQKTLDAGEPESVGVITDFVDPDLTDFIKKIVTEYCTIDFVETRCGYACSDHASASKAGYPSAFVIESDFKYSDDRIHTSGDTLNFLNFDHMLQHARLTLGLVYELAFAKL
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MT_AMBME
Sequence: MDCACATGGSCSCAGSCKCENCKCTSCKKSCCSCCPSECEKCGQGCVCKGGSSEKCSCCN
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, AnMT, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: VGFR1_CHICK
Sequence: MPRQLLSGTVLLGAAFLLAGSTSGSKLKVPVLSVNGRQHVVQAGQTLNLTCRGEMLHSWSLPEALSKDSKRLNVTKYACGRNGTQFCSTLTLSRTQANDTGRYSCRYPTSPVKKKRESIVYVFINDTSNPFVEMHSDIPKIIHMTVGKEMIIPCRVTAPNIAVTLKKIPRETLIPDGKTIIWDNMRGFRIPEATYRFIGLLSCETTIGGHKYSTKYLTHRETNTIFDIKLSTPRLVKLLKGDSLAINCTVKAAWNTRVQMTWTYPGEAMKRGSVTQRIDQKNREANVFYSILVIDKVRDIDKGQYACHVKSGPSNKLVNTTVIVYDKRFINLKRRRKTMLEAVAGRKSYRLPMKVKAFPSPEVTWLKDGLPAAEKCARYMVKNYSLIIKDVAEEDAGNYTIILSLRQWNLSKNLTVTLKVNVKPQIYENAVSSFPDPNLYLLSSKQVLTCTVYGIPPPKITWMWYPCRQNHSKTRRGFCSRTDGSFNLKTGSNIGNRIQSIIERTAIIEGKNKTASTLVVAEAKSSGIYSCVASNKVGKAERNVSFLVTDVPSGFHISLEKVPIEGENLVLSCSANKFMYKDISWILPRTVTNQTKARKALNKEYSITLTLTIRNVSLAHSGTYTCRARNIFTGKEVLQKKDVSIRAQEAPALLRQLMDQTVNTSNSAMLECQVHGIPEPQITWFKNHEEIQQESGIILGPGSRMLFIERVKEEDEGLYQCIATNLKGSVESTAYVTVQGTVERSNLELITLTCTCVAATLFWLLLTLFIRKLKRPYFSETKTNHYLSIIMDPDEVPLDEQCECLPYDASKWEIARERLKLGKSLGHGAFGKVVQASAFGIKKSPTCRIVAVKMLKEGATASEYKALMTELKILIHIGHHLNIVNLLGACTKNGGPLMVIVEYCKYGNLSNYLKSKRNFFSPTKDPSLQGELMKDKKGIEPVEGKKQRLASVTSSESFASSGFQEDKSLSDAEEDEEDAAELYKLPLTMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDARLPLKWMAPESIFDKIYNTKSDVWSYGVLLWEIFSLGASPYPGVQIDEDFCSKLKEGTRMRAPEQATEEIYQIMLDCWRSNPNERPWFSELVKRLGDLLQASVQQEGKDYIPLDTIFTAESGFPPASDPLCNEKFPVPSPNCRSTERARYINTFKIKPPQRIKTFEELPIKEKLVFNDYQADSGMVLASEELKRFTWTGSKQKWTLFGMKGVSRSKESGLSGITKPRSFCSFSCDQLSESKRRYTYGNTVLEKMKACHSPPPDYSSVVHYSQPSI
What is the function of this protein?
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the regulation of angiogenesis, cell survival, cell migration, macrophage function, and chemotaxis.  Acts as a positive regulator of postnatal retinal hyaloid vessel regression (By similarity).  Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.  Ligand binding leads to the activation of several signaling cascades.  Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate and the activation of protein kinase C.  Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, leading to activation of phosphatidylinositol kinase and the downstream signaling pathway.  Mediates activation of MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway.  Phosphorylates PLCG1.  Promotes phosphorylation of AKT1 and CBL (By similarity).
What are the official names of this protein?
Vascular endothelial growth factor receptor 1, VEGFR-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Endosome. Note=Autophosphorylation promotes internalization and degradation. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: LGT_THEMA
Sequence: MKKILAFLLIAAGSTLFFVFLFIFLSKVFSGEILLSRYIFRIGGFELRWYSTLILMGFLISYFVARKRAKNEGINLEEFDELIFYGVIAGIVGARLYYVLFNLKYYRSLWDALKIWEGGLAIHGAVIGALLTGFLYVRLKKPSFTFLQATDLFTSVLPLGQAIGRWGNFFNYEAFGVPTNLPWKMFVPEPYRPVVYKDYSFFHPTFLYESIWDLLVFFMLSVYFKRYRKRHGEVTCLYFVLYSLGRIVIERLRVDSLMIGNIKAAQLLSAVLILLGFTGFLILRSSQEPKRAF
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPA_LISMF
Sequence: MDLGKVITAMVTPIHPEKDKVCKKRIHHLVNHLIKNGSDGLVIAGTTGESPTLSHDEKIKLFRQVIETNDGRAKLIAGTGSNNTAETIAFTKEVAELGGIDAVLIVAPYYNKPNQDGLYAHFAAVSEASDLPVVIYNIPGRSVVNIEPETIIRLAKLPNIVGVKESSGNLDNISKIIAETSDDFQVYSGDDSLTLPILAVGGNGVISVASHVVGNEMQEMIQAFERGEVQKAAQIHRELLPLMNGLFSVPNPAPTKYLLNQQGISVGPVRLPLVDLNAEQGTKLQAILEGLSK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAC17_ARATH
Sequence: MADSSPDSCFKGGKFSAPGFRFHPTDEELVMYYLKRKICRKRLRVNVIGVVDVYKMDPEELPGQSMLKTGDRQWFYFTPRSRKYPNAARSNRGTENGYWKATGKDRVIEYNSRSVGLKKTLVFYRGRAPSGERTDWVMHEYTMDEDELGRCKNPQEYYALYKLFKKSGAGPKNGEQYGAPFQEEEWVDDDNEDVNAIAVAVPEQPVVRYEDARRVDERRLFNPVILQLEDIDELLNGIPNAPGVPQRCIPQVNSEEELQSTLVNNSAREFLPNGQQYNRPSSFDSLETAEVTSAPLVFEKEDFIEMDDLLLIPEFGASSTEKAAQFSNHGEFDDFNEFDQLFHDVSMSLDMEPIDQGTSANLSSLSDSANYTSDQKQQLLYQQFQDQTPENQLNNIMDPSTTLNQITSDIWFEDDQAILFDQQQSFSGAFASPSSGVMPDSTNPTMSVNAQGHEIQNGGGTTSQFSSALWALMDSIPSTPASACEGPLNRTFVRMSSFSRMRFNGKANGTPVSTTIAKKGIRNRGFLLLSIVGALCAIFWVLVATVRVSGRSLLLKD
What is the function of this protein?
Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP).  Transcriptional activator that acts as positive regulator of AOX1A during mitochondrial dysfunction.  Binds directly to AOX1A promoter.  Mediates mitochondrial retrograde signaling.
What are the official names of this protein?
NAC domain-containing protein 17, ANAC017, Protein NTM1-like 7, Protein REGULATORS OF AOX1A 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=Localized primarily in endoplasmic reticulum membrane as dormant form and, upon abiotic stress, is processed into a transcriptionally active and nuclear form after a proteolytic cleavage through regulated intramembrane proteolysis (RIP).
Protein: SYGB_POLNA
Sequence: MTTKNLLVELFVEELPPKALKKLGDAFAGVLAEQLKALGLATAESVVTAYASPRRLAAHISHVWLKADDKAVQQKLMPVSVGLDSAGHATPALLKRLQALGADLSDPVAAVAALKRAPDGKAEALFYNSLVTGATLDTGLQKALEEAIAKLPIPKVMSYQLETDCELPGWTSVNFVRPAHGLVALHGSTVVPVKVLGLKAGNSTRGHRFEAAVDPVVLADADSYAVTLEIDGAVIASFAQRKAEIARQLAEAAAELGGGVQPIEDDALLDEVTALVERPNVLVCEFEKEFLDVPQECLILTMKANQKYFPLLDAAGKLTNKFLVVSNISPEDASFVIGGNERVVRPRLADAKFFFDQDRKRTLASRVEGLGKVVYHNKLGTQGERTERVAEIAVKIAQLLEGDALAGKAGKAAWLAKADLLTDMVGEFPELQGTMGRYYALHDGHSAEIAAAIEDHYKPRFAGDELPRNPVGVVVALADKLETLVGMFGIGNLPTGDKDPFALRRHALGVIRMLVEKDLPLDLGALVGGAAPVFGDKITDATPALLDFIYDRLSGSLREQGYSAQEVDSVVSQKPQRLGDVPKRLAAVRAFAALPEAPALAAANKRIGNILKKEALEVDPHVSELLLREAAEIALYAAMRDVVPTANAQFDTGDYTASLQTLAALRAPVDAFFDGVMVNAEELDLRLNRQGLLKSLHNAMNRVADLSRLVA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1647_BACC1
Sequence: MNTPVSVNEKKDFVKWFLNNYQLKQRECVWILNYLMSHDQLMHKVHFVEHAKYCPRGLVMSANCVKDTPFHFFKQNVMTTDAEKSFHDIRLNRDEDIYIQLNFKSSFQNANYVAVLEENPYLPKHIEVNEKDRLLAERFLEESVFSFRRERLLKQIDEALDKQDKEAFHRLTAELKML
What are the official names of this protein?
UPF0302 protein BCE_1647.
What is the protein family that this protein belongs to?
Belongs to the UPF0302 family.