PharMolix/UniProtQA huggingface dataset:
Protein: MBTP1_RAT
Sequence: MKLVNIWLLLLVVLLCGKKHLGDRLGKKAFEKAPCPSCSHLTLKVEFSSTVVEYEYIVAFNGYFTAKARNSFISSALKSSEVDNWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKFAESDPIVPCNETRWSQKWQSSRPLKRASLSLGSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNERTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKIDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALIASARRLPGVNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETELKNGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVVFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANVPALNELLSVWNMGFSDGLYEGEFALANHDMYYASGCSIARFPEDGVVITQTFKDQGLEVLKQETAVVDNVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVALAFFVVQISKAKSRPKRRRPRAKRPQLAQQAHPARTPSV
What is the function of this protein?
Serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates include SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6, ATF6B and FAM20C.  Cleaves substrates after Arg-Ser-Val-Leu (SREBP2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu.  Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2.  Also mediates the first step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B).  Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.  Cleaves the propeptide from FAM20C which is required for FAM20C secretion from the Golgi apparatus membrane and for enhancement of FAM20C kinase activity, promoting osteoblast differentiation and biomineralization.  Involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes.  It is required for the activation of CREB3L2/BBF2H7, a transcriptional activator of MIA3/TANGO and other genes controlling mega vesicle formation.  Therefore, it plays a key role in the regulation of mega vesicle-mediated collagen trafficking.
What are the official names of this protein?
Membrane-bound transcription factor site-1 protease, Endopeptidase S1P, Subtilisin/kexin isozyme 1, SKI-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=May sort to other organelles, including lysosomal and/or endosomal compartments.
Protein: GRPE_CHLFF
Sequence: MTDSSNEHETENPSVPNPDNEIQDLQQEIATLKAELKEKNDKYLMVLAESENARKRMQKERQEMMQYAVENALIDFLVPIESMEKALGFASQMSDEVKNWALGFNMILQQFKQVFEEKGIVEYSSVGQKFNPFLHEAVETEETTKVPEGIIVEEFAKGYKIGDRPIRVAKVKVAKSPAPQEKEEEKK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGL2_CAEEL
Sequence: MKPCKREIVDFDGIRTHFFPNLALYTCYNEELIAHHSENANRFTSYVFGAVEDSPTEQEILEILFPENANPEAISTGMDACLALGENFLSHYKSFNARLNRQNHSHDLLDAVQEFDEKKILAISRKSRLRKSADSKILTILVNILLSENQEEKFMEICELCSLDLDFDAFVLIKILQLENEENAEEVQIIRENVVDQILEQKPFLAHLLKNGPEKIDEITKLLSVPIIGSSSNQINQLITKICDSSEISDTAVEEHYHQNFKLMNILVRTMIVDRFDLTIDALEQIPVEIKNRMFPGIRIRVLQDTLHFLHQLFKVFLNESQKFDNLAPQSFAKAIKNVWVRHAIIGILDSLKFSLNKDVFNQLVPLIPGSQVSNDVISGKVENAISCAIWIVKTFGTEGSRDSIEKLPWFDSSVELTELINSIEIAVTSVEVEDQTVNFRKIPQKDWLDGNLQKALKTEPTSEKFGISNSLKIKDENQRNQIRGFKDNSKEPNAKVSARFGSKFQRVDSSTKRRLFGGVGVGEPRNCRGFL
What is the function of this protein?
Transient component of P-granule which is involved in germline development.
What are the official names of this protein?
P granule abnormality protein 2.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Localizes to P granules only during postembryonic development.
Protein: COX2_CARSF
Sequence: MTHPLQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIITLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPLLTVKTMGHQWYWSYEYTDYEDLNFDSYMVPTTDLKPGELRLLEVDNRVVLPMEVPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLTSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKYFEDWSVSMT
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIS7_CANGA
Sequence: MAFVKRVTQETNIQLALDLDGGSVSVRESILGKEYASGDGQTIHVHTGVGFLDHMLTALAKHGGWSLILECIGDLHIDDHHTVEDCGIALGQAFKEALGSVRGIKRFGHGFAPLDEALSRAVVDFSNRPFAVVELGLKRERIGQLSTEMIPHFLESFATEARITMHVDCLRGTNDHHRSESAFKALAIAIREARTPTGRDDVPSTKGVLA
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
Protein: CUTC_ECOSE
Sequence: MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVDMPRMEKIMAAAGPLAVTFHRAFDMCANPLYTLNNLAELGIARVLTSGQKSDALQGLSKIMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDEHADEYSRYIVDGAAVAEMKGIIERHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_AFIC5
Sequence: MILGIGSDTIDIRRVQEVIERHGARFIDRIFTEAEQAKAERRAKAPRAWVATYAKRFAAKEACAKALGTGIRQGVWWRDMGVVNLPGGRPTMQLTGGALVRLESLLPPGHEARIDLTITDDWPTAQAFVIISALPRG
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_LEGPL
Sequence: MTNIIDQINAEQMQGKEIPDFNPGDTVLVQVKVIEGNRERLQAFEGVVIAKRNRGLNSAFTVRKISHNVGVERVFQTYSPIVDSITVKRRGDVRRAKLYYLRNLAGRAARIKEKLSGKKGD
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CITG_STRP6
Sequence: MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFMTFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEEIMFCATQGINTHKGLNFSMALLLGATGAYLARTPHLMTDLGCFSKEDTLAICRLVKPMTAHLIQADLGHLNTKKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYLMSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGGAADLLALTFYFAFLEKLL
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: NADE_BURCH
Sequence: MTSADYASRQRAIIAELNVAPHFDAEAEIARRIDFLAQYLRSTGLRTYVLGISGGVDSSTAGRLAQLSVERLRADGYDARFIAMRLPNGVQNDEEDAQRALAFVRADEVLTVDVKPAADAMLRSLVASGHAFETPAQQDFVHGNIKARERMIAQYAVAGARRGIVIGTDHAAESLMGFFTKFGDGGADILPLAGLSKRRVRGVARALGGEELIVMKVPTADLEELRPLRPDEHAYGVTYDEIDDFLEGKPVADRVYETVLRFYDGSRHKRALPYTMFDWPAA
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: RPP_XYLFA
Sequence: MPVITVYRHGGKGGVAPMNSSHIRTPRGEVQGWSPGAVRRNTEFLMSVREDQLTGAGLALTLTVRDCPPTAQEWQKIRRAWEARMRRAGMIRVHWVTEWQRRGVPHLHCAIWFSGTVYDVLLCVDAWLAVASSCGAGLRGQHGRIIDGVVGWFQYVSKHAARGVRHYQRCSENLPEGWKGLTGRVWGKGGYWPVSDALRIDLQDHRERGDGGYFAYRRLVRSWRVSDARSSGDRYRLRSARRMLTCSDTSRSRAIGFMEWVPLEVMLAFCANLAGRGYSVTSE
What are the official names of this protein?
Putative replication protein XF_b0001.
Protein: DDL_CHLCH
Sequence: MSRTTVALFFGGQSAEHEISIISAQSIAAHLDTERFTLLPIYITHSGEWLCDGFARTLLTTNLASKLRGSSREETAAALQQMVRNAAQAPCNRNLAALGVDVAFLALHGSFGEDGRMQGFLETCGIPYTGCGVLASALTMDKALTKLCVADAGIAVAQGTNILSADYLANPNAVEASVEAQVSYPLFVKPASLGSSIGISKVHNREELHPALQAACALDWKVVVESTVKGREIEVAVLGNADPIASVCGEIEPGKEFYDFQDKYMGNSAKLFIPARIPESLQEEVRRSALTAYRALGCSGMARVDFFVDESTNSVVLNEVNTIPGFTDISMYPQMMEASGISYRNLITRLLELALEPLRR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCISB_ARATH
Sequence: MAAHNLCFNSAFVCNVHHQKTQHFPCNAVSKTTSTHAVTFHRRSANYRPPLWDHQYLLSLENIYVKEVETAEKAILFKEEVRKTLNEIEGSIEQLEMIDSLQRLGISYHYKHEIHDILRKIHDQHGEIERETQDLHATSLEFILLRQHGFDVSQDAFDVFISETGEFRKTLHSDIKGLLSLYEASYFSMDSEFKLKETRIYANKRLSEFVAESSKTICREDETYILEMVKRALETPYHWSIRRLEARWYINVYEKKHEMNPLLLEFAAIDFNMLQANHQEELKLISSWWNSTGLMKQLDFVRDRITESYFWTIGIFYEPEFKYCRKILTKIFMLIVIMDDIYDIYGTLEELELFTNVVEKWDVNHVERLPNYMRMCFLFLYNEINQIGYDVLRDKGLNVIPYLKQVWTDLFKTFLTESKWYKTGHKPSFEEYMQNGVISSSVPTILLHLFSVLSDHISDQTLTDDSKNHSVVRSCATILRLANDLATSTEEMARGDSPKSVQCYMYETRASEEEARRHMQSMISDSWDIINSDLKTAHTSSLPRGFLAAAANLNRVVQCIYRHGDGHGSPEKTKTVDYIQSVLFNPVPL
What is the function of this protein?
Predominantly involved in monoterpene (C10) biosynthesis.  Using GPP as substrate, the major product is (E)-beta-ocimene with minor amounts of (Z)-beta-ocimene and myrcene.  Using FPP as substrate, could also be able to synthesize in vitro sesquiterpenes (C15) with (E,E)-alpha-farnesene as the major product and with (Z,E)-alpha-farnesene and (E,E)-beta-farnesene as minor products.
What are the official names of this protein?
(E)-beta-ocimene synthase, chloroplastic, (E,E)-alpha-farnesene synthase, Terpenoid synthase 2, AtTPS02.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GTX3G_NEOGO
Sequence: GLVDVLGKVGGLIKKLLPG
What is the function of this protein?
Has activity against Gram-positive bacteria and S. cerevisiae.  Has non-hemolytic activity.
What are the official names of this protein?
U1-poneritoxin-Ng3g, U1-PONTX-Ng3g, Poneratoxin, Ponericin-G7.
What is the protein family that this protein belongs to?
Belongs to the ponericin-G family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_STAA9
Sequence: MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGPVIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPYELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIRYLQSIQQTLNN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PQQC_RHIME
Sequence: MTTATDRQAFHARLLEIGKERYHDKHPFHAMLHGGGCTTTQVRAWVINRYYYQSRIPMKDAAFLSRCDDPDMRRAWRSRIEDHDGGVEEGGGIRRWLRLAEAVGLDPAYVGSARGVLPSTRFAVDAYVSFVREKPLLEAVASSLTELFAPKIHSERIAGLLEHYAFADDAALAYFRQRLAEVPRDVEFGLAYVLDHADTREKQDAAAQALTFKTDVLWAQLDALYSAYVTPGRIPPGAWDGREGVIREPRAREAAE
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: APO1A_CERAT
Sequence: MRLFLSLLVVVLSIVLEGPTPAQGVPDVSNPFDVLEEFGKTLEDNVREFINLITQSELPAKTRDWFSETFRKVKEKLKINS
What are the official names of this protein?
Apolipoprotein C-I, acidic form, Apo-CIA, ApoC-IA, Apolipoprotein C1A.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURC_LEGPH
Sequence: MNNSEQFLSPRMGRVEQIHFVGIGGAGMCGIAEVLHNQGYRITGSDLGESGTVQRLRSLGIQVYIGHRLENIKGADVVVRSSAVDFNNPEIVAARELMIPVIPRAAMLAELMRFRHGIAIAGTHGKTTTTSLVSSLLAEGGLDPSFVIGGKLNSCGANAQLGKSAYFVVEADESDASFLFLKPMMAVVTNIDADHMDTYEGDFEKLRTTFLEFLHHLPFYGLAVVCLEDEEICRILPAIQRPTLTYGFKEEAHYRAINWTQKGMLSEFVVVRPAPHKQLTIQFQYPGRHNVLNALASIAIATELGVDDDSIVRGLQKFQGVGRRFQMLGEKQFEKGAAIIVDDYGHHPQEILSTIDAFRRVWPERRLVHVFQPHRYTRTQSLHRQFVDVLSLSDELLLMDIYAAGETAIPGVTSENLANEIRSRDKRVTIVSEQSLKATLDEFIKDGDVILMQGAGSIGQIAVNLMKNM
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_WIGBR
Sequence: MMKIFNTLKNKKEKFKPINSNIVNVYVCGITPYDLCHIGHARTLVFFDIMIKYFQYKGYRTNYIRNITDIDDKIINKAFHKKEKYNLLSDFMIKEMKYDLNSLNIMPPNNEPRVTNHISDILEMIKILLEKKHAYISKTGDVVFDISTYRDYGKLSKRFEEKKQLLNNKKNKINFKTKKEKDFVLWKMSKPNEPSWKSPWGHGRPGWHIECSAISDKTLGNIFDIHGGGSDLIFPHHENEIAQSKCANSKFNVNFWVHTGMVMFKKEKMSKSLGNSCLIREIVKKYDADTLKYFLTSSHYRSQITYSVDNMEKSKSAVKRLYRSLHNTNYFYNLPIKEKFTSKFIDAMNDDFNTPKAYSVLFSISRQINYFKNKNPEKANQLSTVLKNLSNIIGILNENPDSYLNNKLKFSKDKINKIKSIIKKRENYRKLKQWEKADEERKKLKYIGVCLEDTIQGTKWFKL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T150A_RAT
Sequence: MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNDSCSPDPAEQGGPKTCCTLDDVPLISKCGTYPPESCLFSLIGNMGAFMVALICLLRYGQLLEQNRHSWINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGAGVAFPAGLLFVCLHCVLFYHGATTPLDMAMAYLRSVLAVIAFVTLVLSGVFFLHESSELQHGAALCEWVFVLDILIFYGTFSYEFGAVSSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI
What is the function of this protein?
Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex.  Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity).  May also play a role in fasting-induced catabolism (PubMed:10858565).
What are the official names of this protein?
Transmembrane protein 150A, Fasting-inducible integral membrane protein TM6P1, Transmembrane protein 150.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes mainly at the plasma membrane; only a minor fraction localizes on intracellular structures.
Protein: SFXN1_SHEEP
Sequence: MSGELPPNINIKEPRWDQSTFIGRAKHFFTVTDPRNILLTNAQLEAARKVVHDYRQGIVPSGLTENELWRAKYIYDSAFHPDTGEKMILIGRMSAQVPMNMTITGCMMTFYRTTPAVLFWQWVNQSFNAVVNYTNRSGDAPLTVNELGTAYVSATTGAVATALGLNALTKRVSPLVGRFVPFAAVAAANCINIPLMRQRELKVGIPVTDENGNRLGESASAAKQAITQVVVSRILMAAPGMAIPPFIMNTLEKKAFLKRFPWMSAPVQVGIVGFCLVFATPLCCALFPQKSSMSVTSLEAELQARIRETYPELRRVYFNKGL
What is the function of this protein?
Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria.  Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors.  May also transport other amino acids including alanine and cysteine.
What are the official names of this protein?
Sideroflexin-1.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ABA2_SPIOL
Sequence: MASTVLYNSLTTSTTVFLRSHLPISSSSPNDELHHQSSVISNCNYYLKKSSFGGQRKKLKENNNYVKAAAVAESLKTYPNEVAGDVPEKKLRILVAGGGIGGLVFALAAKKRGFDVKVFEKDLSAIRGEGKYRGPIQVQSNALAALEAIDMDVAEKVLAAGCVTGDRINGLVDGVSGNWYVKFDTFTPAVERGLPVTRVISRMTLQQILAEAVGEEVITNESNVVDFKDDGNKVSVTLDNGKTFEGDLLVGADGIWSKVRTNLFGHSDAVYSGYTCYTGIADYVPADIDSVGYRVFLGNKQYFVSSDVGGGKMQWYAFYKEAPGGVDQPNGMKQRLFDIFEGWCDNVIDVIIATDEEAILRRDIYDRTPKLTWGQGRVTLLGDSVHAMQPNLGQGGCMAIEDSYELALTLDKAWQKSVESGRPIDVASSLKSYEGARRLRVGVIHGLARLAAVMATTYKSYLGIGLGPLSFLTKLRIPHPGRVGGRFFITPAMPLMLRWILGGNSEKLEGRIPYCSLSEKASNNLQRWFEDDDALERALTGEWTLLPQGSVAGSLKPICLSRKEDEPCIIGGVFHKDSSGMSVALSSPQISEKHAQITCKNGAYFVTDLGSEHGTWITDNEGRNYRLPPNFPTRFHPSDVIEFGTDKKAVYRVKVMATPPKASQNSPSAAVLQTA
What is the function of this protein?
Converts zeaxanthin into antheraxanthin and subsequently violaxanthin.  Involved in the epoxidation of zeaxanthin.
What are the official names of this protein?
Zeaxanthin epoxidase, chloroplastic.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane.
Protein: EFTS_SYNSC
Sequence: MAAAVSAKLVKELRDKTGAGMMDCKKALAATEGDANKAVEWLRQKGIASAEKKSGRTAAEGAIGSYIHTGARVGVLVEVNCETDFVARGDMFQSLLRDVSMQVAACPNVEYVTTDEIPNEIREREKAIEMGRDDLEGKPEQMKEKIVEGRIGKRLKELALMEQPFIKDSSITVADLVKQTAGKIGENVKVRRFTRYTLGEGIEVEENDFAAEVASMQNAG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_SALTI
Sequence: MLEARDLYCERDERTLFRGLSFTVEAGEWVQVTGGNGAGKTTLLRLLTGLARPDGGEVYWQGEPLRRVRDSFHRSLLWIGHQPGIKTRLTARENLHFFHPGDGARLPEALAQAGLAGFEDVPVAQLSAGQQRRVALARLWLTRAALWVLDEPFTAIDVNGVARLTRRMAAHTAQGGMVILTTHQPLPGAADTVRRLALTGGGAGL
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS21_SHESR
Sequence: MPIIKVRENEPFDVALRRFKRSCEKAGILADVRAREFYEKPTTARKRAKAAAVKRLAKKLSRENARRVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL30_PYRNV
Sequence: MIAKVVYPRYAVIRLRGIPTTPRDIAATLDLLRLRRKFTMTVVVGSPDVLGMIEKANDWITWGEIDANTLAEVLKRRGRLVGDRPLTLEHLQRWGWRSFEEVALAFVAGEIDRLSCGRKVPAREGQRAPCIPYLKPFFRLHPPRGGLNSLKLHFSVGGDLGYRGPLINDLIRRML
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL27A_PONAB
Sequence: MPSRLRKTRKLRGHVSHGHGRIGKHRKHPGGRGNAGGLHHHRINFDKYHPGYFGKVGMKHYHLKRNQSFCPTVNLDKLWTLVSEQTRVNAAKNKTGAAPIIDVVRSGYYKVLGKGKLPKQPVIVKAKFFSRRAEEKIKSVGGACVLVA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L27a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_SALEP
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGNVEWFAAPRRLALKVANLAESQPDREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLKTDKGEWLLYRAHVKGESTEALVPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPQILLERGKVIADYEARKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLSVPAEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPTQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLALDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_RHILW
Sequence: MGSFSMWHWLIVLVIVLLLFGRGKIPELMGDVAKGIKSFKKGMTDEDAPDTAKTVDHKADETK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.