PharMolix/UniProtQA huggingface dataset:
Protein: SYP_GLUOX
Sequence: MRLTKAFQPTLKEVPAEAQIASHRLMLRAGLVRQTASGIYAWLPAGLRVLRNIEQIIREEQDAIGAQEVLMPTLQSAELWRRSGRYDAYGPEMLRIQDRHGRDLLYGPTNEEMITDIFGSSVKSYKELPKALYHIQWKFRDEVRPRFGVMRGREFLMKDAYSFDASYEGAVASYRRMMLSYLRIFQRLGVRAVPMVADTGPIGGDLSHEFLVLAPTGESAVFFDAALEEQDWLSRPVDCDDAESLATFFATVTDHYAATDEKHDEAEWAKVPAERKREGRGIEVGHIFYFGTKYTASMGIEVSGPDGAPFHPHMGSYGVGVSRLVGAIIEASHDDAGIIWPASVAPYRAAILNLRQDDEACDAICDRIYGTDPENLLYDDRSERAGVKFNDADLMGHPWQIIVGPRGAKEGKVELKQRATGERFELSVEDALAKIGAA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_CLOB1
Sequence: MSNISVIGTGSYVPNNIITNDFLSTIVDTSDEWIRTRTGILERRISKGENTIYMATESAKEAIKNANIEANDLDLIIVATLTPDNFMPSTACSVQKEIGAMNALCFDISAACSGFIYGLEIACSMLKNSFRNKALIIGAENLSKIVDWEDRNTCVLFGDGAGSAILSKTKEEGILEFHSGSNGLKGEHLTCGVLKANNTPNKNDSLEKNNFIKMNGKEIFRFAVGAMNETIYNIQEKTKWDLNEVKYIISHQANSRIIEYTAKKLNTEKDKFYMNLDKYGNTSAASIPIALDEMNKRGLLNKQDKIILVGFGGGLTFGGVAIVWSI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MECA_STRTD
Sequence: MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDLKEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAFSDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDALPVLQATKWS
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: CAC2_YEAST
Sequence: MEASHLQIYWHDSQPVYSLTFQKNSANDKLFTAGGDNKVRIWKLNRDENGQNGGVRKIESLDFLGSLTHHEQAINVIRFNSKGDVLASAGDDGQVLLWKQEDPNTQQESVVRPFGMDAETSEADENKEKWVVWKRLRGGSGATAAAEIYDLAWSPDNRNIVVACMDNSIRLFDVGAGMLVCGQSDHGHYVQGVAWDPLNQFILSQSADRSLHVYGVILSSAGVVTGLKLRSKIAKAELPCPGDVLRTNYLFHNETLPSFFRRCSISPCGGLVVIPSGVYKVAGDEVANCVYVYTRSGILNSAGGVKNRPAIRIPSLKKPALMAAFSPVFYETCQKSVLKLPYKLVFAIATTNEVLVYDTDVLEPLCVVGNIHYSPITDLAWSEDGSTLLISSTDGFCSYVSIDTETQFGSRIEPPAMHAEPLDTDESAVAAKNQREAGGIVNMLPVKKIPCNSSDSKKRRIHPTPVDL
What is the function of this protein?
Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro.  It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.  p50 and p60 form complexes with newly synthesized histones H3 and acetylated H4 in cell extracts (By similarity).
What are the official names of this protein?
Chromatin assembly factor 1 subunit p60, CAF-1 60 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPF_SORC5
Sequence: MQPGRARPTPPPAQPEHASHGEGHCPGHGPTDPPPHVNWWHGLIGVNNEAAAKGGINALLWRYHNEQNPCDPKNEPPPFLASVLNFGLLALIVVRFGRKPIAEALKKRKQTITQELDNASRLKQEAELRLEEYEDKLTRLEETLAELKAEHAAQAEVEKAHVLAEAEQRRVRMRRDAEFRAEQELKAARAMLLQEAVQNAVVAAEELLRQRIGQQDLDRVNEDYLKAIPAAVSAGARRGAQTTGAAT
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TIG_STRPZ
Sequence: MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGFRKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGKEWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEAAQGDTVVIDFVGSVDGVEFDAGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVTFPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKELEAAQETSYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEMYFQLTGTTQEDLHNPYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYNMPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: TUSD_SERP5
Sequence: MLDYCLVVTGPAYGTQQASSAYQFAQALLAKGHRLSSVFFYREGVLNANQLTAPAGDEFDLVRGWVQLARQHGIELNVCVAAALRRGVTDEQEAAQQGLPAANLQPGFILSGLGSLAEAALSSDRLVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH_CUPPJ
Sequence: MATRKLKAAIIGSGNIGTDLMIKILRHGKHLEMGAMVGIDPASDGLARAARMGVATTHEGVEGLISLPNFADIDVVFDATSAGAHVKNDARLREVKPGIRMIDLTPAAIGPYCVPVVNLDDRLDALNVNMVTCGGQATIPMVAAVSRVAKVHYAEIVASISSKSAGPGTRANIDEFTETTSKAIEVIGGAAKGKAIIVLNPAEPPLIMRDTVYVLSAAANRAEVEASIEEMAAAVQQYVPGYRLKQKVQFDEIPASAPLNIPGLGKFSGLKTSVFLEVEGAAHYLPAYAGNLDIMTSAALATAERMAQAALTA
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: THIM_STRA5
Sequence: MYLEQLKEVNPLTICITNNVVKNFTANGLLALGASPAMSECIEDLEDLLKVADALLINIGTLTKESWQLYQEAIKIANKNQVPVVLDPVAAGASRFRLEVSLDLLKNYSISLLTGNGSEIAALIGEKQASKGADGGKVADLESIAVKANQVFDVPVVVTGETDAIAVRGEVRLLQNGSPLMPLVTGTGCLLGAVLAAFIGSSDRSDDLACLTEAMTVYNVAGEIAEKVAKGKGVGSFQVAFLDALSQMKSEMIMDK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: PIM3_XENLA
Sequence: MLLSKFGSLAHICNPSNMEHLPVKILQPVKVDKEPFEKVYQVGSVVASGGFGTVYSDSRIADGQPVAVKHVAKERVTEWGTLNGVMVPLEIVLLKKVPTAFRGVINLLDWYERPDAFLIVMERPEPVKDLFDYITEKGPLDEDTARGFFRQVLEAVRHCYNCGVVHRDIKDENLLVDTRNGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWVRYHRYHGRSATVWSLGVLLYDMVYGDIPFEQDEEIVRVRLCFRRRISTECQQLIKWCLSLRPSDRPTLEQIFDHPWMCKCDLVKSEDCDLRLRTIDNDSSSTSSSNESL
What is the function of this protein?
Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation.
What are the official names of this protein?
Serine/threonine-protein kinase pim-3, Pim-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_CHLPN
Sequence: MEKRKDTKTTIVKSSETTKSWYVVDAAGKTLGRLSSEVAKILRGKHKVTYTPHVAMGDGVIVINAEKVRLTGAKKGQKIYRYYTGYISGMREIPFENMMARKPNYIIEHAIKGMMPRTRLGKKQLKSLRIVKGDSYETFESQKPILLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CPSF3_DICDI
Sequence: MHHNNHHHGHHGRYQHHHNQHLKRPLKGGTEDDDILEITPIGSGSEVGRSCVLLKYKGKKVMFDCGVHPAYSGLVSLPFFDSIESDIPDIDLLLVSHFHLDHAAAVPYFVGKTKFKGRVFMTHPTKAIYGMLLSDYVKVSNITRDDDMLFDKSDLDRSLEKIEKVRYRQKVEHNGIKVTCFNAGHVLGAAMFMIEIAGVKILYTGDFSRQEDRHLMGAETPPVKVDVLIIESTYGVQVHEPRLEREKRFTSSVHQVVERNGKCLIPVFALGRAQELLLILDEYWIANPQLHHVPIYYASALAKKCMGVYRTYINMMNDRVRAQFDVSNPFEFKHIKNIKGIESFDDRGPCVFMASPGMLQSGLSRQLFERWCSDKRNGIVIPGYSVEGTLAKHIMSEPAEITRLDNVNVPLNLTVSYVSFSAHSDFLQTSEFIQEIQPPHVVLVHGDANEMSRLRQSLVAKFKTINVLTPKNAMSVALEFRPEKVAKTLGSIITNPPKQNDIIQGILVTKDFTHHILSASDIHNYTNLKTNIIKQKLTLPFAQTYHILISTLEQIYEQIIESTESTGGGGNEKPTITIYNEIKLIYNIGVSIILEWNSNTVNDMICDSIIALISQIELNPLSIKVRNPNFNNIDEKEEITKDDIEKEKEKEKEQQDGDDDDDDEIQIKVVSRKSRKLSNKLNTITEVKLLLEQQYGNFKVDENDPLILHFNLDNQKAIIHLETLTVESLDQILKQKIENSIKRIILSVSPIGNNLNQINNQDNENNIKMETDFK
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  Has endonuclease activity, and functions as mRNA 3'-end-processing endonuclease (By similarity).
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 3, Cleavage and polyadenylation specificity factor 3.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYS_DEHMC
Sequence: MLDLKFIRENPELVRKAVADRNTDAPIDEILELDNSRRNLTQELDNLRAKRKIMAKQRDETAIEEGRVLRGQISTLESELSQVDEKLTDRLLRVPNIPDPSVPVGKDESENVVLYYRGEKRNFSFTPKPHWELGEALDIIDFDRGIKLSGSRFYILKGAGARLQRALIAFMLDLHTRKHDYTEIYPPYMIKRECLVASGNLPKFADNLYHDAEEDYWWVPTAEAPLTNLHRDEILSAEQLPIHYVAYTACFRREKMSAGKDVRGIKRLHQFDKVELYKYCKPEDSFAELEKMVADAEEIADALKIPYRLKQLVTADISFGSAKSYDIEMYSPGVDEWLEVSSCSNCTDFQGRRANVRFRRTSEAKPEFVHTLNGSGLALPRVMISVIENYQQPDGSIVIPEVLRPFMGVDVIR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_BURP6
Sequence: MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROE_ERWT9
Sequence: MPSFVVIGNPIGHSKSPRIHQLFAEQTGIAHPYESLCAPLAGFEQTARSFFAKDGGGANVTLPFKQQACKLADELTERAALSGAVNTLKKLDDGRLVGDNTDGIGLLSDLERLDLIKPDDRILLIGAGGAARGVILPLLSFGCRLTVTNRTQEKAEDLAQLFKHSGHIDSMVKEQLAAGRFDLVINATSSGVGGGIPDIPEGLIGDHTRCYDMFYQAGDTPFLHWCRQQGAFQMADGLGMLVGQAAHSFMLWHGIMPQITPAIAVLKAEMGA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CYSB_ECOL6
Sequence: MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDELGIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHTQARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVMLPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK
What is the function of this protein?
This protein is a positive regulator of gene expression for the cysteine regulon.  The inducer for CysB is N-acetylserine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator CysB, Cys regulon transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYFE_SHIFL
Sequence: MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSIFATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAARNIPQNIPEKALFGPAMMALLAALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMENGSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG
What are the official names of this protein?
Hydrogenase-4 component E.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFTS_BACC7
Sequence: MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDFLREKGIAKAAKKADRIAAEGLTFIETNGNDGLILELNSETDFVAKNEGFQTLIKELAAHLLAKKPANVEEAMAQTMENGKKVEEHINEAIAKIGEKLTLRRFEIVSKTDADAFGAYLHMGGRIGVLTVLEGSTDEAAAKDVAMHIAAVNPKYIDRDAVTAEEVEHERQVLTQQALNEGKPEKIVAKMVEGRLGKFFEEICLLDQAFVKNPDMKVRQFVESKGATLKGFVRYAVGEGIEKREDNFAEEVMNQVKGSN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFF_RAT
Sequence: MAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNADLEQGFQDGVPNASVIMQVPERIVVTGNNEDISFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPPTPQSEEIRAVGRLKRERSMSENAVRQNGQLVRNDSMYGISSLDAAVEGASEDMSVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR
What is the function of this protein?
Plays a role in mitochondrial and peroxisomal fission (By similarity).  Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface (By similarity).  May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles (PubMed:23792689).
What are the official names of this protein?
Mitochondrial fission factor.
What is the protein family that this protein belongs to?
Belongs to the Tango11 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein. Peroxisome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
Protein: RBSA2_BURCH
Sequence: MDTILRLSHITKSFPGVKALSDIDLEIARGEIHALLGENGAGKSTLMKILCGIHQPDAGTIEIDGAARHFADYHDAVAAGVGIVFQEFSLIPHLDAVDNLFLGRELRNRWGARDRKRMRAAAAAIFARLGVAIDLDAPIRTLSVAQQQFVEIGKALSLDARILILDEPTATLTPAEAEHLFAIMRELKRQGVAMIFISHHLDEIFVVCDRITVLRDGQYVATTEVARTDVEQLVRMMVGRRIESSFPPKPVLPADAPAVLEVDALQIERDGPVNRFALREGEILGFAGLVGSGRTETALAVIGATRAHRKELRVRGAAAKLADPADALRAGIGILPESRKTEGLVTSFSIRDNISLNNLGKYRSMRWLIDRRGEARTTHDVMRRVGVKAPSIHTEVATLSGGNQQKVVIARWLNHHTSVLIFDEPTRGIDVGAKAEIYGLMRELTARGYAIIMISSELPEIVGMCDRVAVFRQGRIEATLEGDEIDPDTVMTYATAGTRGATHEPA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TILS_MALP2
Sequence: MKHKYLIAVSGGPDSMALLNKKRHLVEAVCHVNYHDREDSDNDEKIVRDYCKKYNLKLFVFDTHKDDVSKYKDINNLQTWYREIRYDFFEKISQELGIKKILIAHQKNDFLESAYMSLNKNKKNLFLGIRRKSKFRSLILIRPLLNKTKKSLEQYCRSKNIEFVIDYTNFWDRYSRNVVRKMMAEWDKKTFQKFYLKVKWFNLKNMFFIKLLDSKFNNWIKQDFDINYFLKIKNNYKESLIYLFLNHIGIKPNENKIEQIIEFINKNKNGSVKKYRLKENQFIEIKNKKILYSIC
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNJC_ECOLI
Sequence: MATPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQALFADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVAFATSALLLFADGGLLYDYFPYFTPPMDRFGIGLGLTLAVKESAFLLWILAAVLSEKWLLQQVIVLDSLGYSRWQCLNWLLLPSVAPALAMAMLAIVAWSLSVVDVAIILGPGNPPTLAVISWQWLTQGDIDQQTKGALASLLLMLLLAAYVLLSYLLWRSWRRTIPRVDGVRKPATPLLPGNTLAIFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLLLWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLKLDGSWTAVVWGHLLWVMPWMLFILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPVLIAFAVGFAVGIAQYMPTLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVAKWVGYVRQGLR
What is the function of this protein?
Probably part of the binding-protein-dependent transport system YnjCD.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Inner membrane ABC transporter permease protein YnjC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMA_ECOUT
Sequence: MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGTEEPWYVVDKDVENNILIVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDADRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_ALKMQ
Sequence: MIILGIDPGIAILGYGIVKYEGNKFKVIDYGAIKTSSKMATPQRLKEIYLRLDELISEYQPDAVAIEELFFNTNTTTAMVVSHARGVAVLAAAIHEKEIYEYTPLQVKQAVVGYGRAEKKQVQQMIKILLNLEQAPKPDDVADALAVAVCHAHSGHFQSLFKVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: GCSH_SALHS
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ACCD_THET2
Sequence: MALERLFRRKRPSGGNRDVPELWTKCEACGAQIYKKEFQENLHVCPKCGHHHRLPAQERVAMLADPGTFQETTRLRPLDPLGFVDTKPYVERLKAYQAETGRPDAILGGTCQIGGVPAVLLVMDYAFAGGSMGSVVGEEIARGAERAAEEGRALVIVAASGGARMQEAALSLMQMAKTVMSLDRVWARRLPYVSVLTDPTTGGVTASFAALADVILAEPGALIGFAGPRVIRQTIRQELPEGFQRSEFLLKHGMVDRVTDRRRLKEELVRVLRHLHPGVAYAPGV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.