PharMolix/UniProtQA huggingface dataset:
Protein: IPO8_MOUSE
Sequence: MDLNRIIQALKGTIDPKLRIAAETELNQSYKIINFAPSLLRIIVSDHVEFPVRQAAAIYLKNMVTQYWPDREPPPGEVIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMCLRVIIRHDFPGHWPAVVDKIDYYLQSPNSGSWLGSLLCLYQLVKTYEYKKAEEREPLLAAMQIFLPRIQQQILQLLPDASHYSVLLQKQILKIFYALVQYALPLQLVNHQTMTTWMEIFRTIIDRTVPPETLQIDEDDRPELVWWKCKKWALHIVARLFERYGSPGNVTKEYFEFSEFFLKTYAVGIQQVLLKILDQYRQKEYIAPRVLQQAFNYLNQGVVHAVTWKQMKPHIQNISEDVIFSVMCYKDEDEELWQEDPYEYIRMKFDIFEDYASPTTAAQTLLYTAAKKRKEVLPKMMAFCYQILTDPNFDPRKKDGALHVIGSLAEILLKKSLFKDQIELFLQNHVFPLLMSNLGYLRARSCWVLHAFSSLKFHNELNLRNAVELAKKSLIEDEEMPVKVEAALALQSLISNQAQAKEHMKPYVRFIMQELLHIVRETENDDVTNVIQKLICEYSQDVASIAVDTTQHLAEIFGKVLQSDEYEEIEDKTVMAMGILHTIDTILTVVEDHPEIIQQLENICLRIIDLVLQKHVIEFYEEILSLAYNLTCHTISPQMWQLLGILYEVFQQDCFEYFTDMMPLLHNYVTVDTNALLSNPKHLEVLFTMCRKVLCGEAGEDAECYAAKLLEVIILQCKGRGIDQCIPLFIQLVLERLTRGVKTSELRTMCLQVAIAALYYSPELLFHTLEQVQLPHNPGPVTSQFINQWMNDTDYFLGHHDRKMCIIGLSVLLELQNRPPAVDAVAAQILPSILFLFLGLKQVCATRQTVNRENHSKAEKVDIEENEEISSEEEEETSVSAQAMQSQIGRSEEEDDDDWDEEVLEETALEGFSTPLDLDNSVDEYQFFTQALLTVQNRDAAWYQLLVAPLSEDQKRKLQEVYTLAEHRRTLAAGQFHI
What is the function of this protein?
Involved in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1.  Acting autonomously, may serve as receptor for nuclear localization signals (NLS) and promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.  In vitro mediates the nuclear import of the signal recognition particle protein SRP19.  May also be involved in cytoplasm-to-nucleus shuttling of a broad spectrum of other cargos, including Argonaute-microRNAs complexes, the JUN protein, RELA/NF-kappa-B p65 subunit, the translation initiation factor EIF4E and a set of receptor-activated mothers against decapentaplegic homolog (SMAD) transcription factors that play a critical role downstream of the large family of transforming growth factor beta and bone morphogenetic protein (BMP) cytokines.
What are the official names of this protein?
Importin-8, Imp8, Ran-binding protein 8, RanBP8.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NUDL_SALTI
Sequence: MDTSRLTLDHFLSRFQLLRPQMTHETLNQRQAAVLIPVVRRPQPGLLLTQRAIHLRKHAGQVAFPGGAVDSTDASLIAAALREAQEEVAIPPQAVEVIGVLPPVDSVTGFQVTPVVGIIPPNLPWRASEDEVSAVFEMPLAQALQLGRYHPLDVYRRGNSHRVWLSWYEHYFVWGMTANILRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: RS14Z_HELMI
Sequence: MAKTSMIVKQSRTPKFRVRAHNRCKICGRPHAYMRKFGMCRICFRNLAYKGEIPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: TGCE3_SCHPO
Sequence: MTLNGNIMKYCLEKGEILISFLLIALESMFRICTVILPSPLRNWFYEQSKKVYSYFLPELLVDDNANKLTDARDTIDLCALHGYDLEEHFVRTTDGYLLGLHRVYKKKKGKIEELNYLPPVLFIHGLMMNSESWVCNLKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPKFWDFSLDSIAIFDIPSIVKYILSVNSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPAIAPKKYSGRTVKSIIHANSQLLYLMFGRNSMLGSAVFWQAVLYPPVFAKIVDLFLRFFLSWTGKNISETQKIVAYSHLYSFTSVKCFVHWAQITRRKVLQMYDDSPGFKPSYYTNLNRIARYPIENIRLPITLVYGSNDNMVDIETLKTQLPPLSQCIQIPNYEHLDIIMGDTKKDIVIQQVVEQLNHVIAGDYFESIKEEFGLDTELVDGVMNHTI
What is the function of this protein?
Probable lipase.
What are the official names of this protein?
Probable lipase C14C8.15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Golgi apparatus. Membrane; Single-pass type II membrane protein.
Protein: SEC5B_ARATH
Sequence: MSSSDDLDEDELLQMALKEQSQRDVTYQKPPSANSRKPVTNLVQQPRRQKRAAAPPSKGGAKASRKPSMDEDDESEVELLSISSGDEDEGNDRGRGGGGDGGGGRGRGGSGKERGRARKEDDRAWDGVEPDCWKRVNEAELARKVRDMRESRTAPSVTQNLDRKVSGADKKVVLTSLQSFPRGMECIDPLKLGIIDNKTLRLITESSESLSKAEKVDNALREKLVYTSDHFDPKLFISRIHQETSAADLESGALALKSDLKGRNLQRKQLVKDNFDCFVSCKTTIDDIESKLKRIEDDPDGSGTTHLFNCMKSVTSRANRAFEPLFERQAQAEKIRSVQGMLQRFRTLFNLPSIIRSSISKGEYDLAVREYKKAKSIALPSHVNLLKRVLEEVEKVMQEFKGTLYRSMEDPKIDFTSLENTVRLLLELEPESDPVWHYLNVQNHRIHGMLEKCTFDHEARMEILRNQVHERALSDAKWRQIQQNGVQLSDDTSSMEDNQVQVDQPLEESARREKDALRGRYIKILTAVIVYHLPTFWKTALSVFTGKFAKSSQVNDTSASKAEEKAEEARYSSHSLEEIAGMIRNTISVYEAKVQSTFHDFDESYILHPYMSDTIKEVSKACQAFEAKESAPHSAVMALRKVKVEITKIYIQRLCSWMRASTEEISKEETWIPVSILERNRSPYSISYLPLAFRSIIVSGMEQINMMILSLKGEAARSEDMFAHIEEILISVRLAFLNCFLDFAAHLEQIGADLSQRTTKRESWQNGYSNDHQEEQSINAPESVVDPHRQLLMILSNIGYCKDELASELYNKYKYTWLQSRRNDEDISDLQDLMMSFSGLGEKVLEHYTFAKANLIRTAATNYLLDSGIQWGAAPPVKGIRDAAVELLHTLVAVHAEVFAGAKPLLDKILGTLVEGLIDTFLSLLDENRSDDLSSIDANGFCQLMLELEYFETILKPYLTVDATESLKSLQGAVLEKAIESISETVENNPGGHQRKPTRGSEDAISDDKQSSVSPDDLLALAQQCTSGMLQLELEKTRLNSACFIETIPLDPVPPVAKAAYSRTSTDSPSRNYRESQPMGSPVQARPRRR
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane during regulated or polarized secretion.  Involved in polarized cell growth and organ morphogenesis.  During cytokinesis, involved in cell plate initiation, cell plate maturation and formation of new primary cell wall.
What are the official names of this protein?
Exocyst complex component SEC5B, AtSec5b.
What is the protein family that this protein belongs to?
Belongs to the SEC5 family.
Protein: RIMM_ECO5E
Sequence: MMSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLTTRSIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_SYNY3
Sequence: MARIAGVDLPRDKRVEIALTYLYGIGLSRSHEILDATGVSPDVRVKDLSDEDALKLRTYIDENYEIEGDLRRWEAMNIKRLGDIGTYRGRRHRQGLPVRGQRTRTNARTRRGRRLTVAGKKKTPAKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL21_LARHH
Sequence: MYAVVKTGGKQYRVAVGEKLKVEQIPADIDSQIVLEEVLMVAGGDEVKVGTPLVAGATVKATVVSHGRGEKVRIFKMRRRKHYQKHQGHRQNYTEIRIDEISL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CLC_DROME
Sequence: MDFGDDFAAKEDVDPAAEFLAREQSALGDLEAEITGGSASAPPAASTDEGLGELLGGTASEGDLLSAGGTGGLESSTGSFEVIGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGESISKTKLASRNAEKQAATLENGTIEPGTEWERIAKLCDFNPKVNKAGKDVSRMRSIYLHLKQNPIQVQKST
What is the function of this protein?
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
What are the official names of this protein?
Clathrin light chain, dClc.
What is the protein family that this protein belongs to?
Belongs to the clathrin light chain family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic face of coated pits and vesicles.
Protein: Y1736_OCEIH
Sequence: MEQTFYQFLMTYRGKLEKDDNSELAEWAFRNHNFPKHSNTYDEISNYLEWNSPFPSATVTFDSLWNEYEWKKAAY
What are the official names of this protein?
UPF0346 protein OB1736.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: ARGJ_PROMP
Sequence: MSDGEEKPDGFSFAGIAAGLKDSNKKDLALILAPENSICSGLFTQSIVRASCVDICEQRIKKSSGLIRAILINSGQANACTGDYGIQHTLFATKEVSQLLGINEEEVLMCSTGVIGIPIQIKNLIDNLPNLVKELKTNSLQNAAEAILTTDLVDKKITIETFIEGRKVKISGFAKGSGMIYPNMATMLAFLTCDVGVDKEEWDKMISIAVKKSFNAISVDGETSTNDAFIGINSGKKIDKKFLSKIQSGIDIVCQSLAKNIARDGEGANCLLEVLVEGAKSNSDAIKIAKSICNSSLVKTAINGCDPNWGRIISAAGNSGIDFKLDFLDLYIGDFQILKKGKLNKYDSKKVANYMQTRMNGKYLVEDIVSISLHLNSGSEKGTAWGCDLSKKYVEINSEYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURT_PYRHO
Sequence: MIKLRDELGTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVVAVDRYANAPAMQVAHRSYVGNMMDKDFLWSVVEREKPDAIIPEIEAINLDALFEFEKDGYFVVPNARATWIAMHRERLRETLVKEAKVPTSRYMYATTLDELYEACEKIGYPCHTKAIMSSSGKGSYFVKGPEDIPKAWEEAKTKARGSAEKIIVEEHIDFDVEVTELAVRHFDENGEIVTTFPKPVGHYQIDGDYHASWQPAEISEKAEREVYRIAKRITDVLGGLGIFGVEMFVKGDKVWANEVSPRPHDTGMVTLASHPPGFSEFALHLRAVLGLPIPGEWVDGYRLFPMLIPAATHVIKAKVSGYSPRFRGLVKALSVPNATVRLFGKPEAYVGRRLGIALAWDKDVEVAKRKAEMVAHMIELRTRSSDWHDQNYEKRKHLLR
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: ATPA_ORYSA
Sequence: MATLRVDEIHKILRERIEQYNRKVGIENIGRVVQVGDGIARIIGLGEIMSGELVEFAEGTRGIALNLESKNVGIVLMGDGLMIQEGSFVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEIVASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQDVICVYVAIGQRASSVAQVVTTFHEEGAMEYTIVVAEMADSPATLQYLAPYTGAALAEYFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNSLLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELQAFAQFASALDKTSQNQLARGRRLRELLKQSQANPLPVEEQIATIYIGTRGYLDSLEIGQVKKFLDELRKHLKDTKPQFQEIISSSKTFTEEAEILLKEAIQEQLERFSLQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SYD_TOLAT
Sequence: MRSIYCGQVTSSHVEQTVTLCGWVHRRRDLGGLIFIDMRDREGIVQVFFDPDKPEAFALASELRNEFCIRVTGVVRARPDSQINKDMATGEVEIFAHGLEIINRAEPLPLDFNQTNTEEQRLKYRYLDLRRPEMAASLKTRARITSFVRRYMDEHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFLNAEQVRELMENLIRGLWQNIIGVDLGQFPIMTFDEAMRRYGSDKPDLRNPMEMVDIADLLKDVSFAVFAGPANDPKGRVAALRVPDGAQLSRKQIDEYTQFVSIYGAKGLAWMKVNQADSGLAGVQSPVAKFLNDEIVREILSRTSAQDGDIIFFGADSKKVVCDAIGALRLKLARDLDLVENCWKPLWVVDFPMFEEDGEGGVTAMHHPFTAPKDFTPAQLEADPLAAYANAYDMVINGYEVGGGSVRIHRGDMQQTVFRAIGISEAEQKEKFGFLLDALKFGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTDAPSFANQQQLSELAIQTTVKAAE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEY1_PENRW
Sequence: MAERRPSGLERSPTAPPVLSNGHFASIGAEGDASSYEHGVQVIDENKEFNPDLSKYLSLENVTPAGFNYHLISVFGSQSTGKSTLLNHLFGTQFSVMSELERRQTTKGIWLSNNKKQGDAGSAERMADNILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQVGLYQGANMGLLKTVFEVNLQLFLKDKHTTHRSLLFFVIRDFIGTTPLKNLQKTLLEDLSRLWDTISKPAGLEKSTIHDYFDFQFYGLPHKGYQPDQFVTEANKLGLRFREGHRDPKRDALKGEFSEGGVFLPEYHRRIPADGFSHYAEGIWDQIVNNKDLDLPTQQELLAQFRCDEILREVMIGFDEAITAFEDKQAESVRVGAPEVLGGLGVAMRAARVKTLKSFETEASRYHKGVYQRKSAELQGKVDTRLKALFHGQLSAAHKSGIRDFSDSVSAAVKDGQKKGGSYDFAEIVAKETQSSLEKFEEVAHSTLVDGASWSNCTQELSLFKKELAEVSARLRRDEMRRLATRVERWVQSRLGESVGLEFNALGSGRAGGGAPENGEKPTEKDFWDRIWNLFEETVLDAERRFTDRASSFDASIDEVDVGLWRLRRKSWGVLRAKIEEEMIEGNLLLKLRENFEDKFRYDEAGVPRIWRPTDDIEGIYTRARESTLTVIPLLSRFRLERTTAPPPLDRWIGHTPSTATPADEEDLAPIGGVDEHEGKSLEEEMTILSDAKRQELTVRFKKAADGVYVEAKRSAIGGMTQVPLYFYGLLLALGWNEIWAVLRNPAYFILLFAFAIGAYITYQLNLWGPMLKMTEAASQQALEEGKRRLREFLESSDTGRQAIAMSAGERAGSSGRKEEYEMSDMQKRASNANDDLDDM
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein sey1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: WDR75_XENLA
Sequence: MVSQCQIRVVRSGGSKLDYRRSVFSADGKYLICVSGDFIKVYSTSTEECIHALQGHRKLVTGIELNPKNHLQLYSCSLDGTIKLWDFTDGILIKTFLIGCKFLSLYTSATDDLVFAVTLKNNDSASSQLVSVKLPKSASQECEAKEISVIIEDVSHLPKCTAIGRQCLYVASVKGVHLSIYYFKTKKSFRFSLKATSKKGANNIFTVVACHPSEDCIATGHMDGRIRLWRNFNHKKEYTYTSLHWHHDSVMDLAFSAQGTKLLSGGVESVLVQWPYGSEEKKEFLPRLGAAIEHISVSPHGTLYCTSHTDNKISIIDTSLKVSGIIQGLLKGTVVKTGLIVDPRSNALVLNGKPGHLQFYSLLNDRHLYNLDIVQQEFIHQAGLQYMDLVKASFSSTGRWLATVEELQGGEDSMDLEMQMKLWEYQDKSQSFVLNTTINRPHEDHITSLCFRDEGNSEKEAPTLVTTGKDGLFKVWMLNNNYDIYKQSSSWLCDFVGGYHKNQATNCCFSEDGSLLAVSFDEIITVWESSTWDLKQTFCQPPGKIRNLCFGRMSCSKYLVASTNNGFICCWNLLTCALEWRAQLDATVLQPDPLSENIAVVSCSKRWSNLFLFQPSEPRPFYTQKNICQEKVQWAVFVPKEIPEFVKSESHQWLNKSQLYFLTEKQDLLTFSSKSTEERLTPLSKQLAVEESLPVTPFHLLLGKKRQEEQEKLDAQSVRAAPSFHRGYQNSAIREVLHTPAHVLPPASVLCTVFVNSLLISKKSQSTEESKEDEEMKSEHSEADSSDETEEMESQKRFPSAFSLDVAAMLPKFQEKELRRIRRTDYSWISSL
What is the function of this protein?
Ribosome biogenesis factor.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
What are the official names of this protein?
WD repeat-containing protein 75.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NIKR_SHIDS
Sequence: MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
What is the function of this protein?
Transcriptional repressor of the nikABCDE operon.  Is active in the presence of excessive concentrations of intracellular nickel.
What are the official names of this protein?
Nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: IHFA_AGRVS
Sequence: MAGKTVTRADLAESVFRKVGLSRTESAELVETVIDEICNAIVRGEMVKLSSFATFQVRAKNERIGRNPKTGEEVPISPRKVMTFKASNVLKQRILRSHLARKAKQKPANPAA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: COAX_AZOVD
Sequence: MIVELDCGNSFIKWRIIDAFSRVLSSGVVESIEELVHALDEARTSHEFAHCRMVSVRSDDEVARLESVLAQRFGLRVSAVRPASCLAGVRNGYLNHERLGLDRWMAVVAAYRLSAGACLVLDLGTAVTADFVDADGEHRGGFICPGLPLLRRQLREHTRRIHYDAVAANDLTGGSFAPGRSTAEAVERGCVLMLRGFVASQLELAKEYWGDRFEIFLTGGDASLVADVLPRAKVVPDLIFTGLAIACPIPS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELF5_BOVIN
Sequence: MLDSVTHSTFLPNTSFCDPLMSWTDLFSNEEYYPAFEHQTACDSYWTSVHPEYWTKRHVWEWLQFCCDQYKLDANCISFCHFNISGLQLCGMTQEEFMEAAGVCGEYLYFILQSIRSQGYSFFNDPDETKATLKDYADSSCLKTSGIKSQDCHSHSRTSLQSSHLWEFVRDLLLSPEENCGILEWEDREQGIFRVVKSEALAKMWGQRKKNDRMTYEKLSRALRYYYKTGILERVDRRLVYKFGKNAHGWQEDKL
What is the function of this protein?
Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation.  Binds to DNA sequences containing the consensus nucleotide core sequence GGA[AT] (By similarity).
What are the official names of this protein?
ETS-related transcription factor Elf-5, E74-like factor 5.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALCA_BORPE
Sequence: MNREIYDFVAIGIGPFNLSLASLSAPLRGVRTLFLDKKSGFDWHPGMLIETSTLQNPFLADLVSLADPRSEYSYLNYCKLTNRIYSYYMRENHYLSRAEYTRYCQWVAARLPNLRFGCDVQGVLHDPESHSYLVTGQHTMSGQRFMFRCRKLVLGLGSQPYLPACCDRRAAPFIHSADYLRHKYELQGRASITIVGSGQSAAEVFHDLLRESGRHDYSLAWITRSPRFFQMENTKLTLELISPDYTEYFHDLPEARRQEILTQQNSLYKGINASLINQIYDLLDEKVHDGDNRYTLLTNSELRACRYDPLQERFQLDFQHLDCDRPFSHATDGLVLATGYSHEIPACINPIHDRIAWNADGSYRIGRNYAIDHEGSEIFVQNTGLLSHGVTNPDLGFCCYRNSQILRELTGTEHYRIETRTALQEFSPPADGVLKHRPARRAERRPTVAARPLMDIHRATL
What are the official names of this protein?
Alcaligin biosynthesis enzyme.
What is the protein family that this protein belongs to?
Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
Protein: EFGM_EMENI
Sequence: MRCPSLARLPHRAVSGLTRTPVRFQSQAFLTARCASTAALRSATPVHQSVLNRRYQQTRNASGTAAAVLEAAAQTPDSLSQEAIIENLDPVEAERLSRVRNIGIAAHIDSGKTTCTERVLFYTGRIKAIHEVRGRDSVGAKMDSMDLEREKGITIQSAATFCDWVKKDEDGKEQKYHMNLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMRRYNVPRISFVNKMDRMGANPFKSVDQINTKLKLPAAAVQVPIGAEDEFEGVVDLVRMKAIYNQGSNGENIVVKDEIPEKVRELAEERRRMLIETLADVDDDMAEIFLNEEEPTEKQIKDAIRRATIGLKFTPVFMGSALANKSVQPMLDGVIDYLPNPSEVQNTALDKKRNEAQVKLVPYNALPLVCLAFKLEESSFGQLTYIRVYQGTLRKGSYVFNARTDKKVRIPRIVRMHSNEMEDVSEIGAGEICAVFGVECASGDSFTDGQLGYTMSSMFVPEPVISLSIKPKHSKDYANFSKAMARFQREDPTFRVSFDPESEQTLISGMGELHLDIYVERMRREYRVDCETGPPQVAYRETISQRVEFDHLLKKQSGGPGDYARVVGWLEPTGKLEENQFEEQIVGGSISEKFIFACEKGFHLSCEKGPLIGHKVLGTKMVINDGATHMTDSSEMAFKNATQQAFRKAFQEGNPAVLEPMMKTVVTAPAEFQGDVIGLLNKRGATINDSEVGVDEFTVYADCSLNGMFGFSSHLRAATQGKGEYTMEFSHYEKAPPQEQRELVKKYLQAQADRHKK
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TATA_FRACC
Sequence: MGDIGAPELIIIILVVVVLFGSKRLPDAARSLGRSLRIFKSEIKGLHDDEAPAPTAAVAAAPTQVTGPAPAAPHTPPSAEPATPATGGSGNRSA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PUR2_LISMF
Sequence: MNLLVVGSGGREHAISKKLLESNNVENVYCAPGNDGMRLDNIQLVAISETDKAGLIDFAKKAEIAFVIVGPEVPLLEGVVDALEEAGIKAFGPKANAALIEGSKDFAKQFMEKYAIPTAASKTFTDYAEAKAYLDERGVPIVIKADGLAAGKGVTVALEMEEAVLALKDMMLEEKFGDASLKVVIEDFLAGEEFSLMAFVNGEEVYPMAIAQDHKRAYEGDKGPNTGGMGAYSPVPHISETVVDEAVEKILLPAAKGMVKEGRYFRGILYAGLILTAEGPKVIEFNARFGDPETQVVLPRLESDFAALIDALLHNEKPDVRFKKSGITLGVVLASAGYPEHYEKGNKLTGLNDVAEDVAIYHAGTKQDENDDFISDGGRVLLLAKEAETMTDARTLLYPEMQKLDNPNFFYRIDIGTKAE
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: DNAA_SHEPW
Sequence: MAVSLWQQCIARLQDELSAQQFSMWIRPLQAEMEGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEQMGADAPKLRFDIGSRPSAKPVVQATAAIRPKPAASKAVEKPTFNAPQAEPAITANHRSNINPTYQFDNFVEGKSNQLGKAAALQVSENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNKPDAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDKYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.