PharMolix/UniProtQA huggingface dataset:
Protein: RL24_DESAP
Sequence: MGKMNVRKGDKVVVITGKDAGKRGKIIEAIPDKNKVIVEGVNVVKRHSRPTRKLPQGGIQEKEAPIDSSNVMLLCARCHKPTRVGRRILDDGTKVRVCKKCGEALQ
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: VIPR1_RAT
Sequence: MRPPSPPHVRWLCVLAGALACALRPAGSQAASPQHECEYLQLIEIQRQQCLEEAQLENETTGCSKMWDNLTCWPTTPRGQAVVLDCPLIFQLFAPIHGYNISRSCTEEGWSQLEPGPYHIACGLNDRASSLDEQQQTKFYNTVKTGYTIGYSLSLASLLVAMAILSLFRKLHCTRNYIHMHLFMSFILRATAVFIKDMALFNSGEIDHCSEASVGCKAAVVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSVFITIWTVVRIYFEDFGCWDTIINSSLWWIIKAPILLSILVNFVLFICIIRILVQKLRPPDIGKNDSSPYSRLAKSTLLLIPLFGIHYVMFAFFPDNFKAQVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWSSKSQHPWGGSNGATCSTQVSMLTRVSPSARRSSSFQAEVSLV
What is the function of this protein?
This is a receptor for VIP.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Vasoactive intestinal polypeptide receptor 1, VIP-R-1, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, PACAP-R-2, PACAP-R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANCY_SYNSC
Sequence: MPTMGGLHQGHGELIRRASEQGPVLVSVFVNPLQFGPAEDFDRYPRTLEADRGLAECCGAHALWAPSVDAIYPSGLPSAVSRSAPAGLQTHLCGASRPGHFDGVVTVVARLLQLVEPSCLWLGEKDWQQLVILRRLVVDLDLGVVVKGVPTVRESDGLALSSRNQYLFPADRARAAALPAALRHADPSDPESSVRQSLAKAGLEVEYVERVDPRTLQPCGPETAISLLAAAVRCGTTRLIDHVFLMTRQPLVAIDGPAGAGKSTVTRAFAERMGLVYLDTGAMYRSVTWLVQQNGVDHQDAVSIAPLLNDLDLQLKSLPGGGQQVLVNGQDVSDAIRSPEVTASVSAVAAHRCVRQALTAQQKAMGAKGGLVAEGRDIGTAVFPDADLKVFLTATVGERARRRALDLEQRGFPVPERSELEAQIAERDHLDSTREEAPLVQADDALELVTDGMSIEAVIDALVGQFRSRVGEEAWPTPAG
What is the function of this protein?
Catalyzes the transfer of a phosphate group from ATP to either CMP or dCMP to form CDP or dCDP and ADP, respectively.
What are the official names of this protein?
Bifunctional pantoate ligase/cytidylate kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGALB_ASPNG
Sequence: MRWLLTSSALLVPAAALVRPDGVGLTPALGWNSWNAYSCDIDADKIVTAANEVVNLGLKDLGYEYINIDDCWSVKSGRNTTTKRIIPDPDKFPNGISGVADQVHALGLKLGIYSSAGLTTCAGYPASLGYEEIDAQSFAEWGIDYLKYDNCGVPTNLTDQYTYCVPDSTDGSNYPNGTCVNLTDAAPQGYDWATSTTAKRYQRMRDALLSVNRTILYSLCDWGQADVNAWGNATGNSWRMSGDITATWSRIAEIANENSFLMNYANFWGYPDPDMLEVGNGNLTLPENRAHFALWAMMKAPLIIGTPLDSIDTSHLTILSNKPLLTFHQDAVIGRPAYPYKWGYNPDWTFDPEHPAEYWSGPTSSGEVFVLMLNSEGEVKTRSAVWEEVPELKDRGTKKNSKEKKGFKVTDAWTGKDLGCVKDKYEVKLQAHDVAVLVVGGQC
What is the function of this protein?
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
What are the official names of this protein?
Probable alpha-galactosidase B, Melibiase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ALGG_PSEPK
Sequence: MNLHPHLRHSLLASALLLASGLATAAEPQVIAKELQQAKTYTVASAPIEPLQMDPPKLPDLTGFTAEAVQKKIDRRHKGKVSLRRMFQEDTLKEFVGGDNKAAEWVQRQHGIPQAIFVDDGHVDLTELSKKVPKQYFSEVEPGVYLARLPIVVGQKGILEIDGKVKQLRLSQEGGAFLVNDGKLFVTDTQVTGWREKDNGPATFRSPKEFRPFLLSWGGTETYIVNTKMASFGYAKSKSYGVSISQYTPNMAKRMGRPEPTGWIIGSEFSDMWYGFYCYETQDFVIKDSTYRDNIVYGIDPHDRSHRLIIAGNTVYGTKKKHGIIVSREVNDSWIINNKSYDNKLSGVVIDRNSVNNLVAYNEIYRNHTDGITLYESGDNLIWGNKLVNNRRHGIRVRNSVNIRLYENVAMANGLVGVYGHIKDLSDTDRDIALDPFDTKVSLIVVGGELSANGSGPLSIDSPLSVELYKVSMLAPRKASGISLNGVLGERQDEILDLLVRQQKAVLIDPVERQTEMID
What is the function of this protein?
Catalyzes the epimerization of beta-D-mannuronate to alpha-L-guluronate during the synthesis of the linear polysaccharide alginate.  In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE.
What are the official names of this protein?
Mannuronan C5-epimerase, Poly(beta-D-mannuronate) C5 epimerase.
What is the protein family that this protein belongs to?
Belongs to the D-mannuronate C5-epimerase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HLDD_ECOK1
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: CLPX_PROMM
Sequence: MAKFDAHLKCSFCGKSQDQVRKLIAGPGVYICDECIDLCTEILDEELVDSQGNPRHSSESNRKSATASHKSGKPAPTLATIPKPQQIKSFLDKQVVGQEAAKKVLSVAVYNHYKRLAWQGDGQGETDLSATRLHKSNILLIGPTGCGKTLLAQTLAELLDVPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVEHAQRGIIYVDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFIGLEDVVQKRLGRNAIGFMPSDGRGRSRANRDLQASQVLHHLEADDLVRYGLIPEFIGRIPVSAVLEPLDSQALESILTEPRDALVKQFSTLLSMDNVQLEFESDAVEAIAQEAHRRKTGARALRGIIEELMLDLMYDLPSKKNVKKFTVTRTMVDEHTGGKVLPLPANDERSHQESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SKY1_DICDI
Sequence: MSDIQQDSTSTTLGGTSLGGTSLGGTSLGGTSLGGTSLGGTSLGGTSLGGSTTTSTTTPKSTNSKNKKKKQTSSNNNNNNNNNNNNNNENNRDNDAGSSNKSFMPLNNNEDEGTKDYKQGGYHPVRRNDVYGNRYQVVDKLGWGHFSTVWLCNDKDTPITTSSSSSSTTTTTTSSSSNGNGNGNGGNVIGYKQVALKIVRSARTYSETAEDEIKILNAISKYNAQDKCVARLLDHFTHRGPNGRHYCMVFELLGNNLLDLIKHHRYRGMPITLVKTLMKQTLIALDYIHTKCKIIHTDLKPENVLLEKSFDFFTSNDYIWSEKYGYFKNRTSSSNKQSQQQQQPQQQQSQQNINDYSDDSDDSHSDYSDSEDELKNKGNKKSSNRDRDNNKNKNIKKDDNKSSVNEINNISKENTDNKDLNSSEENKKEEEQQQNKKEEPTTTTTTATATATTTTTTGTEEFKFVNGISYKFKKNNELFNENHYPRAQLVDLGNACWTDKHFTDDIQTRQYRAPEAIVKAKWGTPVDIWSAACMAFELATGDHLFKPKSGKGFEKSDDHLALMIELLGKPPRFIFAGGDESRVYFTHKGDLRKIPDLSDQWPLFSVLTEKYKFSIQEAKDFEAFLLPMLNYLPEKRATAKDCLNHTWLKDVPPFLN
What are the official names of this protein?
Probable serine/threonine-protein kinase sky1, SRPK1-like kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
Protein: UBA4_EMENI
Sequence: MEDLETRCASLRTEIAAAEAQLTKLKRELHEAEGAALRAQSQKTASANATTGQRTKSKWPLHGEEYRRYGRQMIVPQFGLQGQLKLRDAKVLIVGAGGLGCPAALYLAGAGVGTIGLVDGDTVEASNLHRQVLHRSRNVGKLKVDSAIEYLRELNPHPTYIAHQAHLTPREAPDIFKDYDLILDCTDNPATRYLISDTAVLLGKPLVSASALRTEGQLMVLNNPPQPPGDKTGGPCYRCVFPKPPPANSVTSCADGGILGPVVGTMGVLQASEAIKVLTSAGESVEATPPSLLIFSAYSSPQFRTIKLRSRRPNCAVCSAEATVTLESVRSGSMDYVFFCGTVDPADILSPEERISPSEYGNVDSAGAQRHIIDVREKVQFDICSLENSINIPMSTILASAYSAPTLDADEPKRLPSWLPPEVAHESNKPIYVVCRQGNDSQTVVRKLKELGLDHGGERPVVDIKGGFRSWREQVDPDWPDY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a.  Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity).
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase uba4, Common component for nitrate reductase and xanthine dehydrogenase protein F, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ5_LEIDO
Sequence: MLHYTRLGRNMGLGDAYVKKVFDSVATKYDMMNDVLSLGIHRIWKKHFVEDCVCPLPGSKFLDVAGGTGDIAFRITDSIRARGQSFGIVPKTLDGTKVVVCDINAMMLKEGQKRAEREGYMDIDWVCASGEELPFEDGAFDSYTVSFGIRNFSDRPKALREAFRVLKVGGALHVLEFSRVTCPLLSVPYELWSYGFMPQAGRMLADEESYRYLVDSIRAFPDQETFAQMIRDAGFGYVRYENLTGGIACIHTGVKTTPTPITPTTSSDIPAQNTSEATCEVKPEPNSA
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ZEAD_MAIZE
Sequence: MAAKIFCFLMLLGLSASVATATIFPQCSQAPIASLLPPYLSPAVSSMCENPIVQPYRIQQAIATGILPLSPLFLQQPSALLQQLPLVHLVAQNIRAQQLQQLVLANLAAYSQQHQFLPFNQLAALNSAAYLQQQLPFSQLVAAYPRQFLPFNQLAALNSAAYLQQQQLLPFSQLADVSPAAFLTQQQLLPFYLHAMPNAGTLLQLQQLLPFNQLALTNSTVFYQQPIIGGALF
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
Zein-alpha PMS2, 19 kDa zein PMS2.
What is the protein family that this protein belongs to?
Belongs to the zein family.
Protein: RPIA_LACGA
Sequence: MDKSEQDQLKKEAATKAAMMVESGSVLGVGTGSTVAFFIDALGERKEKENFSLKHIVTTSNRSKKQLEGLGFQVDELADIDQADLTVDGADRVDDNLDGIKGGGGALTLEKNVAINSKKVIWIVDESKLVHHLSGFPLPVEVLPVSAEQNFKRFEEEGLKPQWRLDDNGKRYVTHYGNYIIDLAADPTPVPHGLADYLDHTVGVVEHGLFLDMCDEVIIAHSDGTIEDKKRK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: YM65_CAEEL
Sequence: MIKYHVSRSARLWAYWSTLPHRMLKKYPEQTIFYATFGVATLLIGGYKMKKYLTESDKPFYRGYYDVVRSNDPIAQNWRKPEEYPAPYLLSSVETAH
What are the official names of this protein?
Uncharacterized protein K12H4.5.
Protein: RB11A_RAT
Sequence: MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity).  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity).  The small Rab GTPase RAB11A regulates endocytic recycling (PubMed:11163216).  Acts as a major regulator of membrane delivery during cytokinesis.  Together with MYO5B and RAB8A participates in epithelial cell polarization.  Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.  Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells.  Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane.  Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane.  Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes (By similarity).  May also play a role in melanosome transport and release from melanocytes (By similarity).
What are the official names of this protein?
Ras-related protein Rab-11A, Rab-11, 24KG.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Recycling endosome membrane; Lipid-anchor. Cleavage furrow. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Note=Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Localizes to the cleavage furrow. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis.
Protein: AGBR_MYCBO
Sequence: MRFVVTGGLAGIVDFGLYVVLYKVAGLQVDLSKAISFIVGTITAYLINRRWTFQAEPSTARFVAVMLLYGITFAVQVGLNHLCLALLHYRAWAIPVAFVIAQGTATVINFIVQRAVIFRIR
What is the function of this protein?
Required for arabinosylation of arabinogalactan (AG), an essential component of the mycobacterial cell wall.  Probably acts as an anchor protein recruiting AftA, the first arabinosyl transferase involved in AG biosynthesis.
What are the official names of this protein?
Arabinogalactan biosynthesis recruiting protein Mb3818.
What is the protein family that this protein belongs to?
Belongs to the GtrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYE_NOSP7
Sequence: MTVRVRIAPSPTGNLHIGTARTAVFNWLFARHHGGKFILRIEDTDLERSRPEYTDNILEGLRWLGLNWDEGPFFQSQRLDLYKEAVQKLLDQGLAYRCYTTSEELEALREAQKARGEAPRYDNRHRNLTPEQRAAYEAEGRSYVIRFKIEDGREIVWNDLVRGKMSWRGSDLGGDMVIARASEEGSGQPLYNFVVVVDDIDMQITHVIRGEDHIANTAKQILLYEAMGAKIPEFSHTPLILNMEGRKLSKRDGVTSISEFQKMGFTAEGLVNYMTLLGWSPPDSTQEIFTLETAAKEFGFERVNKAGAKFDWDKLDWLNSQYIHNTPVDKLTDLLIPFWEAAGYKFDGGRDRAWLEQLVTLISQSLTRLVDAVPQSQLFFSDTVEFSEEGSTQLKQEGSTAVLEAIVTALENQPQLSEAAAQDIIKQVVKEQKVKKGLVMRSLRAALTGDVHGPDLIQSWLLLNQIGLDKSRLSRAITEAN
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_STAAS
Sequence: MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELALLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKPPSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGADGALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: GLNA_SUIBO
Sequence: MAYQYHNDLLAPYLALSQGDKVQAEYVWIDGDGGLRSKTMTMTKKTTDIGQLRIWDFDGSSTNQAPGGDSDVYLRPAAIFKDPFRGGDNILVLAETFNNDGTPNRTNHRHHTKKVMDLAKDSVPWFGLEQEYTLFDADGTPFGWPKGGFPGPQGPYYCGAGTGKVFARDLIEAHYRACLYAGVNISGINAEVMPSQWEFQVGPCEGISMGDHLWMARYLLVRIAEQWGIKVSFHPKPLAGDWNGAGCHTNYSTKVMREPGGMKYIDEAIEKLSKRHAEHIAVYGEDNDLRLTGRHETGHIGDFSSGVANRGASIRVPRHVAAQGYGYLEDRRPASNIDPYRVTGIIVETTVLDK
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLP5_PLAVT
Sequence: MRVLVLCAAVLTCFVTVSAQEVAYDRIEPFEEVKPDCPLNELALMFKPQLYISNGCHPYPAIDSEGHFSNGLSAFRIGTSCDGSSKGSQVYGRAFYNSDRNIMEIMYAWYFPRDRMITPVYIGHRNAWEHAIVYVDVAKDDPQLLAVAARGMWSYRTYNPPRSDYLDDEKSFKLQYKWIGISHHYLKGTKNPGEFQDLIMWDNMTVKARHNIQEKTWFGSKAPIADDKFFKYLEKARPF
What is the function of this protein?
Secreted effector that acts as a pathogen-associated molecular pattern (PAMP) recognized by the plant immune system (PubMed:35152834).  Seems not to induce necrosis in Nicotiana benthamiana leaves but significantly improves disease resistance of Arabidopsis thaliana to Hyaloperonospora arabidopsidis and causes an inhibition of plant growth which is typically associated with enhanced immunity when over-expressed in Arabidopsis (PubMed:35152834).
What are the official names of this protein?
NLP effector protein 5, Nep1-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the Necrosis inducing protein (NPP1) family.
Protein: LAT_RAT
Sequence: MEADALSPVELGLLLLPFVVMLLAALCVRCRELPASYDSASTESLYPRSILIKPPQITVPRTPATSYPLVTSFPPLRQPDLLPIPRSPQPLGGSHRMPSSRQNSDDANSVASYENQEPARKNVDEDEDEDDYPEGYLVVLPDSSPAAVPVVSSAPVPSNPDLGDSAFSMESCEDYVNVPESEESAEASLDGSREYVNVSQDAQPVIRAELASVTSQEVEDEEEEDVDGEEAPDYENLQELN
What is the function of this protein?
Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development.  Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells.  Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules (By similarity).
What are the official names of this protein?
Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Note=Present in lipid rafts.
Protein: RS8_HISS2
Sequence: MSMQDPIADMLTRIRNGQAANKVAISMPSSKLKVAIANVLAEEGYIANVKVSEGVKPELEITLKYFQGKPVVESIQRVSRPGLRIYKRKNELPKVMGGLGVAVVSTSKGIMTDRKARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS3_MYCTA
Sequence: MGQKINPHGFRLGITTDWKSRWYADKQYAEYVKEDVAIRRLLSSGLERAGIADVEIERTRDRVRVDIHTARPGIVIGRRGTEADRIRADLEKLTGKQVQLNILEVKNPESQAQLVAQGVAEQLSNRVAFRRAMRKAIQSAMRQPNVKGIRVQCSGRLGGAEMSRSEFYREGRVPLHTLRADIDYGLYEAKTTFGRIGVKVWIYKGDIVGGKRELAAAAPAGADRPRRERPSGTRPRRSGASGTTATGTDAGRAAGGEEAAPDAAAPVEAQSTES
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: AQP1_PIG
Sequence: MASEFKKKIFWRAVVAEFLAMTLFIFISIGSALGFQYPVRNNQTSGAAQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISVLRAVMYIIAQCVGAIVATAILSGITSSLPGNSLGLNSLAPGVDSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGFSVALGHLLAIDYTGCGINPARSFGSAVITHNFQDHWVFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDGDDINSRVEMKPK
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
What are the official names of this protein?
Aquaporin-1, AQP-1, Aquaporin-CHIP, Water channel protein for red blood cells and kidney proximal tubule.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TTC7A_MOUSE
Sequence: MAAKGAHGTHLKVESEVERCRAEGQWDRMFELARHLQMLGISGGGSSNRRNSPSGRFTTLDTDDFVKLLLAEALLEQCLKDNHDKIKNSIPLLEKTDHRLNEAKDHLSSLLNNGKLPPQYMCEAMLILGKLHYVEGSYRDAVSMYARAGIDDISVENKPLYQMRLLSEAFVIKGLSLERLPNSVASHIRLTEREEEVVACFERASWVAQVFLQELEKTSNNSTSRHLKGSLSPDYELSYFLEAALQSAYVKNLKKGNIVKGMRELREILRTVETKATQNFKVVAAKHLAGVLLHSLSEDCYWSPLSHPLPEFMNKEENSFVTQTLRKPHLYEGDNLYCPKDNIEEALLLLLISESMATRDVVLSRAPEQAEDRKVSLQNASAIYDLLSITLGRRGQYVMLSECLERAMKCAFGEFHLWYQVALSMVACGKSAYAVSLLRECMKLQPSDPTVPLMAAKVCIGSLHWLEEAEHFATVVIGLGEEAGESLPKGYLALGLTYSLQATDATLKSKQDELHRKALQTLERARELAPDDPQIIFYVALQLALVRQISSAMERLQEALTMCRDDANALHLLALLFSAQKYYQHALDVINMAITEHPENFNLMFTKVKLEQVLKGPEEALVTCRQMLRLWQTLYNFSQLGGLEKDGSFEGLTVKKQNGIHLTLPDAHDADSGSRRASSIAASRLEEAMSELTLTTSVLKQGPMQLWTTLEQIWLQAAELFMEQRQLKEAGFCIQEAAGLFPTSHSVLYMRGRLAEVKGSFEEAKQLYKEALTVNPDGVRIMHSLGLMLSQLGHKSLAQKVLRDAVERQSTFHEAWQGLGEVLQDQGQNEAAVDCFLTALELEASSPVLPFSIIAREL
What is the function of this protein?
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane.  The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity).  In the complex, plays a central role in bridging PI4KA to EFR3B and HYCC1, via direct interactions (By similarity).
What are the official names of this protein?
Tetratricopeptide repeat protein 7A, TPR repeat protein 7A.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Localizes to the cytosol and is recruited to the plasma membrane following interaction with EFR3 (EFR3A or EFR3B).
Protein: ARLY_BRUME
Sequence: MSEQKSSNQMWGGRFASGPDAIMEEINASIGFDRKLYAQDIQGSLAHAAMLAKTGIIAAEDHKQIENGLKTIRKEIEEGKFTFSRKLEDIHMNIEARLAELIGPAAGRLHTARSRNDQVAVDFRLWVKQELEKTAAALKNLIEAFLERAEEHAATVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDLSRVRDAIERIDESPLGAAALAGTGFPIDRHMTAKALGFREPTRNSLDSVSDRDYALEFLSLAAICAGHLSRLAEEIVIWSTPQFNFVRLSDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLVALLTIMKGLPLAYSKDMQEDKEQVFDAAENLELAIAAMAGMVRDLTVNVAAMKKAAGSGYSTATDLADWLVRTLGLPFREAHHVTGRAVALAESRKVDLAKLSLEELQSINPAITAEVFGYLTVEKSVKSRQSFGGTAPQEVRRQIRYWKKRIAKA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CISY1_MYCTU
Sequence: MADTDDTATLRYPGGEIDLQIVHATEGADGIALGPLLAKTGHTTFDVGFANTAAAKSSITYIDGDAGILRYRGYPIDQLAEKSTFIEVCYLLIYGELPDTDQLAQFTGRIQRHTMLHEDLKRFFDGFPRNAHPMPVLSSVVNALSAYYQDALDPMDNGQVELSTIRLLAKLPTIAAYAYKKSVGQPFLYPDNSLTLVENFLRLTFGFPAEPYQADPEVVRALDMLFILHADHEQNCSTSTVRLVGSSRANLFTSISGGINALWGPLHGGANQAVLEMLEGIRDSGDDVSEFVRKVKNREAGVKLMGFGHRVYKNYDPRARIVKEQADKILAKLGGDDSLLGIAKELEEAALTDDYFIERKLYPNVDFYTGLIYRALGFPTRMFTVLFALGRLPGWIAHWREMHDEGDSKIGRPRQIYTGYTERDYVTIDAR
What are the official names of this protein?
Citrate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.