PharMolix/UniProtQA huggingface dataset:
Protein: GUAA_BARQU
Sequence: MSISHPDTVLIIDFGSQVTQLIARRVRAMGVYCEIVPFQLALEGVKRLRPQAVILSGSPYSVIDDGSPRAPMEIFEIGVPVLGICYGEQVMCVQLGGKVESGHRREFGRAFLEVQEKSALFDGVWEKGSCYQVWMSHGDHVAALPEGFRVIGTSKGAPYAAIADEKRCLYAVQFHPEVVHTPDGTKLLQNFVHKISGLKGNWSMASYRDQAIATIRKKVGKSRVICGLSGGVDSSVVAVLLHEAIGDQLTCILVDHGLMRKNEAEEVLKLFRDHYNIELIHVNAANIFLNALEGETDPEKKRKTIGRLFIEVFEEETKKIEGVEFLAQGTLYPDVIESVSAIGESVTIKSHHNVGGLPERMNMKLVEPLRELFKDEVRSLGRELGLPEQFLGRHPFPGPGLAIRCPGAVTREKLEIIREADAIYLDEICKAGLYDEIWQAFVVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYPYDMEFLSKTAARIINEVRGINRVVYDITSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GSH1_DICDI
Sequence: MGFIAEGNTLAWEDSVKYLEYIREHGVIQLLNIIKNNKDKVTEDFKWGDEVEYILINNDNYKLKLRANEILDLLMLEEKRNPTTVEHLWRPEYGRFMIEGTPGSPYIGLGKQLLSIQSNLKSRRENVEKYLKPNESILTITSYPRMGCKNFTDPQGEVKGPIAESKFLPDTVINPHFRFSTLTANIRKRRGGTVSINIPMYRDKNTPEYLDQICTYEKVPPILDDSDNSQTNISSPSNQPFNIYMDAMGFGMGCCCLQTTFQLPNIDDARTVYDQLAPISPLMLSLTAASSIFKGYLSDIDARWTIISQSVDDRNKEELGKAPLNNNKFVINKSRYDSIDSYIGSKSKSFRSEYNDLDLVYDKDVYQKLIENGVDSLLSKHFAHLFIRDPLVIYSDKIEIDDEKNTDHFENIQSTNWQTVRFKPPPPSSSIGWRVELRPMEVQLTDFQNSAFVVFSAILVKAIQDLKLNFYIPITKVDENLKTAHKRASVINDKFYFRKNIYNNTPNGSIENEYELMTINEIFNGKGGDNKGLIGVIRDYISTLDFDNETTELVNKYIKFISKRASGEIKSISTWTREFVQNHPAYNHDSIVNDEIQADYLQRCLDISNGTIYDSSIQGDKDDYYC
What is the function of this protein?
An essential enzyme in glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) biosynthesis, GSH is essential for growth and differentiation to prespore stage (PubMed:15993406).  Catalyzes the condensation of glutamate to cysteine (PubMed:15993406).
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 3 family.
Protein: BANP_DANRE
Sequence: MMSEQGLVEIVQIAVADLNHEGHQTDVLENNEDSDQPGRKRARIEISQETSIKSMLISISQAICQRLDSMEAKLQVLEVTCRGLVEKLDTVMGKNQSTTQVPMVSGSPFGATQTCDKVRCVVPQTNVIVSGDRAKTEETSPRTSDSLENLLSNTVGRGRQKTIVLKVPVQEEIQDDQESGSETSDSVSNSGQPQNNNNVTLITLNSEEDYPTGTWLGDENNPEMRVRCPVSPADMLHISTNCRTAEKMALTLLDYLFHREVQAVSNLSGQGKHGKKQLDPLMIYGIRCHLFFKFAITESDWYRIKQSIDSKCRTAWRRKQRGQSLAVKSFSRRTPASQSSSDGVSAAETSAIETSTQQALHYALAGATQQVQIHRIGEDGQVQVIPQGHLHIAQVPQGEQVQITQDSEGNLQIHQVHVGQDGQVNVLRGPQLIAVASTDGTGGVDASPLQANDIQVQYVQLGTVTDHTGAVQAEALTPALQAEMDVKEAIQLQQAENGEVVQIQMPGT
What is the function of this protein?
DNA-binding protein which may repress cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels.  Promotes TP53 activation, which causes cell cycle arrest (By similarity).
What are the official names of this protein?
Protein BANP.
What is the protein family that this protein belongs to?
Belongs to the BANP/SMAR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CITD_VIBCM
Sequence: MKIAHPAFAGTLESSDLQVRIEPNNDGGIELVLDSTVEQQFGHAIRQVVLHTLDAMQVRDALVTIEDKGALDCVIRARVQAAVMRACDVQNIEWSQLS
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_UROTA
Sequence: MMTYIAFILSTILVVSFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNYGGSFLGLMVFLIYLGGMLVVFGYTTAMAMEEYPEVWVSNKTVLSLFVLGFMAELLFAGYCISDEKLEIVLNFNGQGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSLVIGVLVVMEITRGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1313_BRASB
Sequence: MLICVPGILSKDDVAEFRHIMDSSDWEDGRSTAGAQSAMVKRNEQLPPDSEVARKLGHRIISAMTANPRFLAAAIPQHIFPPLFNRYAADSGHHFGIHVDNAVRGDKLTGLRIRTDLSVTLFLSEPEEYDGGELVIEDLYGSHEVKLPAGDLVLYPASSLHMVTPVTRGVRIASFFWLQSMIRDPLARSMIFDLDTTIQDLSRRMGRDDPEMVRLTGLYHNLIRYWAET
What are the official names of this protein?
PKHD-type hydroxylase BBta_1313.
Protein: KEX1_COPC7
Sequence: MLSAIWTGFVTLFLCSFVQGAPADNVLPSAASFYVPSIPGIIPNPDYRLQIYAGHLPAESNKTLLASNDVTAHLYFVMVKNRRVADKERVVFWFNGGPGCSSFDGLMMEVGPWRWDGQPEGKESFIVKEGGWEEYTTMVFVDQPPGTGFSFTSTDQYAKTMKDAQWHILEFLRNFYQVFPEVLTMDTYLAGESFAGQWIPYFADAILESSLQIPLRGIAIGNGWMDARRQYLSYLDYSLKMGLIKDNSEDWKEVKAAHDRCEAHLEKLEGDPIHIRECGSIIMKVINQKRPDNEKGEKMCLNMYDVRFTDTSPACGLNWPPEMHAITHFLGRKDVVRALHAERHPGSWVECRRPVHRAFKDGEEESSITVLPRVLSKIPVLIFAGDQDLICNYVGLENMIKSLTWNGETGLGTVETQSWSVNSTATGTWVESRNLTYVKIFNASHMAPFDLPHVTHDMMLRFMGVNFSSIVGGSAMIPSSLGDAAKPVFVGGHLPQPSTPALPAGKTPEQDKAMWEAYYNAGSAALVLVLIMLVIGLFIWYRRRKSRLQLPSNQSGELAEESIPLRSEMEDRGGNGVSNGGAWKGKARASEPVFEVGDSDEDEPSPYRKPDGGGDRNV
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: RL6_TRIEI
Sequence: MSRIGKLPIPIPKKVTITIEGQKVTVKGPLGELSRVLPPEIAVKEQENTIIVKPQEQSRRARQRYGLCRTLVANMVEGVSKGYEKRLVIQGVGYRAQVQGKTLVLNVGYSKPVEMPAPEGINIAVENNTNVIVNGINKELVGNTAAKIRAVRPPEVYKGKGVRYAGEVIKLKAGKSGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MSRQ_PASMU
Sequence: MLSLFRIIIHVCCLGPVAWLAWVLLSGDESQLGADPIKEIQHFLGFSALTILLIMFILGKVFYLLKQPQLQVLRRALGLWAWFYVVLHVYAYLALELGYDFSLFVQELVNRGYLIIGAIAFLILTLMALSSWSYLKLKMGKWWFYLHQLGYYALLLGAIHYVWSVKNVTFSSMLYLILSIMILCDALYGLFIKRKGRSTSAHTGKD
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF12_ACISJ
Sequence: MAKEELIEMQGSVTEVLPDSRFRVTLDNGHQLIAYTGGKMRKHHIRILAGDKVSLEMSPYDLTKGRITFRHLAGRGPGPGTGSSSGNR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 261R_IIV6
Sequence: MASFNIENPLQQLEQSGLAGVTLNDNAAPAANVIYSSLKSGGGGSTPPATTTSLGTIQLAGVLTGIATSPQLAAGSVGASQLAPGAVNASSIAPGSITGSSLAPGTITSTQLAPGSVGSSQIANGAVGSSQIANGAVGSSQIANGAVGASQIANGAIGPMQLAPLSGPSELIGSNSTSPNAMDITLGPSLQMSPAGVLSVNPSAVTVAPSTTTSLGTIQLAGVLTGTATSPQLAAGSVGASQLAPGAVTSSSIAPGSISGSSLAPGSVTSSQLAAGSVGTSQLAPLPAPSELLGSSSTSSAVTDIMLGSGLSMTGSVLSVNASTAVPPATSSSLGTVQLAGALTGSATAPSLAANSVGSSQISAGAVGATQLGANVVGNGQLAPLSGPSELIGSNSSSPAASNITLGTGLSMSSGGVLSVNASTAVPAATSSSLGTIQLAGALSGTATSPTLSAGSVGATQIVAGSVGATQLGANVVGNSQLAALSGPSELIGSASGSSDATNIILGSGLTMTGNTLNSTLGTIPIPVSQGGTGLTTIPSGSFLLGNGTSPVTTASSIPATMVTPNLVGSVNGVVPSSAGGNVAVVLGNVTTGVLSAQPAQPQPNGNIYVVSGDPTPANNGRTFISNGTTWNEVTNNIATTDARYVQLAGSTMNANANLVFPSTGHVTLNQTTFASTDAVTAQYVASQIASGSTPAATTTSLGTIQLAGSLTGTATSPSIASGVVTQTNMASNSIGSAQIIAGSVGATQLGANVVGTGQLAPLSANSELLGSNSSSPAATNITLGSGLSMTGSVLSVNASTAVPAATSSSLGTIQLAGALTGSATSPTLATGSVGATQIVAGSVGATQLGANVVGNGQLAPLSAPSELIGSNSASPNATNISLGSGLSMSSGGVLSVDASTAVPAATSSSLGTIQLSGALSGSATSPTLSAGSVGSTQIADGAVGASKIANGAVGATQIAANSVGTGQLAALSGTSQLIGSNSSSSAATNITLGTGLSMSSGGVLSATAIAPAPATSTSLGTIQLAGSLSGTATAPTIANNAIGTAQLANNAVETAQLANGAVGLSQLAPLPATSELIGSSSGSTTASAITLGSGLVMSAGGQLSVNLTGVSIPAATSSSLGGIQMLGDLTGSVATAPTVAPGAITLAKMANLSGNSQLIGSSKTSTTPTNITLGPSMSMTNSQLNGPISFLTSGNNPNTTAPSDRPAQQNTLYSGTDGSIWLYNGTNYVKINSGLTSTGSIVASLTNITFGNLVVQVGGIVNNANCSIFVMFNDSQTHQCTASLFSTYAANGSAQNIGNMYQPISGTFVGLQKVWGGGFLSQVGGMQTYVLIDQTFGKQWNISISAIASNSFFVSVLSVI
What are the official names of this protein?
Uncharacterized protein 261R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 261R/396L/443R family.
Protein: RS3_ECO57
Sequence: MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation (By similarity).
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y4LS_SINFN
Sequence: MARIGYARTFTTDQNLAAQIAALRNAGCEVIREEQKSGASLEGRPQLMTILDFIHAGETFVITRIDRLARSLRDLQVIVDRLKAKGAHLVATEQPADTSTAAGKAFFDMLGVFAGFETNLRRERQAEGIAAARKRGIYKGRPPKIDRAEILLRLQQGQGPSKIARDLGISRGTVYQVRKGVFE
What are the official names of this protein?
Integrase-like protein y4lS.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: TT39A_MOUSE
Sequence: MGQKGHKDSLYDCKGSPVSSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQSLCQRHRRKSSMTDSFSNLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYSKGESHRHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGATGHSFRAVLCVMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMAYFYADLLSKENSWSKATYIYMKAAYLSMFGKEDYKPFGDNEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYLSPNPISLPIPALEMMYIWNGYAVIGKQPTLTDGMLEVITKAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRSISANEKKIKYDHYLIPNALLELALLFMEQGRNEEAIKLLESAKQNYKNYSMESRTHFRIQAATLQARSSLEDGNRSLVSSVSL
What are the official names of this protein?
Tetratricopeptide repeat protein 39A, TPR repeat protein 39A.
What is the protein family that this protein belongs to?
Belongs to the TTC39 family.
Protein: RNFH_ECODH
Sequence: MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: RIR2_LEIAM
Sequence: MKPVAAGAEVLPADKVAQGTNAEEEPLQQENPFRYVLFPIQYHDIWRKYKEQESCIWTVEEIDLGNDMKDWATLNDGERHFIKHVLAFFAGSDGIVIENLAQRFMSDVKVPEARAFYGFQLMMENIHSETYSVLLDTYITDSEEKLRLLHAIQTIPCIQKKAEWPVRWIGSSASFQQRLIGFAAVEGIFFSGSFCALFWLKKRGLMPGLTFSNELISRDEGLHTDFACLLYNSHIKHKLPRERVLEIIVDAVNIEREFICDALPVRLIGMNAELMAQYIEFVADRLLVSLGEEKHYRSTQPFDFMEMISLQGKTNFFEKRVGEYQKAGVMSTEGTSKKFSLSEDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small subunit, Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: PUR9_STRZJ
Sequence: MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGVDTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNLYPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAANGETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENPQQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHMNPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSYTDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQVVTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQAKDRLNGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQEFIEAADKYGLTMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL31_ACIB5
Sequence: MRADIHPKYEKLVATCSCGNVIETRSALGKETIYLDVCSACHPFYTGKQKNVDTGGRIDKFKQRFAGMSRSIKR
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: HIS4_METBF
Sequence: MVFEVIPAVDMRGGKCVQLVQGVPGSEIVSIDDPVEVALDWVRKGAKTLHLVDLDGAIEGERKNAPIIEKIVSACQKKGVQIQVGGGIRSFEDAASLLELGVSRVILGTAALKNPELVQQLSSTFGNEHVTVALDAKNGKISIKGWTEECAQTPVEMGRKFEELGAGSLLFTNIDTEGLMQGVNPVPTKNLVESVSIPVIASGGVSSLQDLRTLKKTGASGVVVGSALYTGRFTLEAAIETTQQE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_DESVM
Sequence: MPKHGKKYRSAIEGRDIAEILTLEDAVAKSLGASFAKFDETVDVAICLGVDPKYSDQMVRGAVTLPHGLGKTVRVAVFCKGDKEAEAKAAGADFAGAEELVAKIKEGWLDFDKAIATPDVMALVGQIGRVLGPRGLMPNAKTGTVTFDVATAVKETKAGRVEFKVDKAGVLHAPLGKVSFGPEKILDNLKSLLDTVNRLKPATAKGTYMKAMAVSTTMGPGFKVDPTTIKKFLEG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RCN1_TAKRU
Sequence: MDVLGFICAVFLGTVVLHAKPTVRKDRVLYQDPELLRQATNEDNNSFQYDHEVFLGKEESKTFDQLSPEESKDRLSKIVDRIDGDGNSYITTDELKAWIKRVQKRYVYENVVKVWADYDLNKDNKISWEEYKQATYGYYLSNPEEFDETTDQFSFKKMLPRDERRFKRADLDGDSAANREEFTSFLHPEEFEHMKDIVVLETLEDIDKNSDGHVDEDEYIADMFAHEDRGPEPEWVKTEREQFSDFRDLNKDGKMDLDEIRHWIMPQDYDHAQAEARHLVYESDKDKDQMLTKEEILDNWNMFVGSQATNYGEDLTRNHDEL
What is the function of this protein?
May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.
What are the official names of this protein?
Reticulocalbin-1.
What is the protein family that this protein belongs to?
Belongs to the CREC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: PTYBC_ECOUT
Sequence: MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPDIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQLKARQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVTADAQGTLPDALNFMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPTATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVSGFIFTTLFGCRNVNLD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylmuramic acid (MurNAc) transport, yielding cytoplasmic MurNAc-6-P.  Is also able to take up anhydro-N-acetylmuramic acid (anhMurNAc), but cannot phosphorylate the carbon 6, probably because of the 1,6-anhydro ring.
What are the official names of this protein?
PTS system N-acetylmuramic acid-specific EIIBC component, EIIBC-MurNAc.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL18_BRASB
Sequence: MSRAKVTNARRKQRVRLSLRRSAGGRPRLSVFRSSKHIYAQVIDDQKGETLASASSMEKEMRSSGNTGADIDAAKAVGKLLAERAVKAGIKEVVFDRGGYLYHGRVKALADAARESGLSF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: SLX4_VANPO
Sequence: MDFRQAQRNLELIEEVAKNSQDSDEPIIDEDDLKEGKVEEEGEGTQIPSMPFSDDDDSDNNSKDTFKETPLELVDKEEAIEDKAPNDDEPVVSVEEKIATQEPEPEEQIFMNTQIQGQLDDIEQEDNLRSKLSNFKYASEESSSVQVIKRSNERKLKSKKITKPKLTKTSKRTKTNSNPSTQQTLDEIKISRSENILKLLSGKHGKVKDMINHQRNVEKKVKLVKNKNSNIITYDTYNSEEWLRIMKLILEKFPSANDMEVKQVYHYIYGEEQEQEYDNLWEASQIPLASMREEAYNEDNQIDRKIPNIPNSTQTRVEVMSLSQVMDDVSIIEESKKTTIDSEREMHIYEVPDSTDDEDSRIIRVISGSDEVASIVAESEFSTETESTSTQFFTADGNMVDGVIDLTQGSFKAVTKLFSPLKVDTLLSINKNKEKVQVAVTRTSTRFSNLGSGPVGLEETPRLAPDEAATPPTVISRSPQSTRTPQATRLPNPNITVMYEVNKCELQSSNSYQSRSSEDIRIVNQYDIDVRDSQDEYDSATEKCLIEFAVTNSATPSVQPEDVMNVISSQSVQKLRQDLKTIGLKPVRTKAKMIEALMAASQVLDTDNVDQEQTREALYDQLTSMIKQIPELVSKISRFEPITMEELVLQLIEVNPFADHIDESTIKEWADIQGITLRNN
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPAG4_HUMAN
Sequence: MRRSSRPGSASSSRKHTPNFFSENSSMSITSEDSKGLRSAEPGPGEPEGRRARGPSCGEPALSAGVPGGTTWAGSSQQKPAPRSHNWQTACGAATVRGGASEPTGSPVVSEEPLDLLPTLDLRQEMPPPRVFKSFLSLLFQGLSVLLSLAGDVLVSMYREVCSIRFLFTAVSLLSLFLSAFWLGLLYLVSPLENEPKEMLTLSEYHERVRSQGQQLQQLQAELDKLHKEVSTVRAANSERVAKLVFQRLNEDFVRKPDYALSSVGASIDLQKTSHDYADRNTAYFWNRFSFWNYARPPTVILEPHVFPGNCWAFEGDQGQVVIQLPGRVQLSDITLQHPPPSVEHTGGANSAPRDFAVFGLQVYDETEVSLGKFTFDVEKSEIQTFHLQNDPPAAFPKVKIQILSNWGHPRFTCLYRVRAHGVRTSEGAEGSAQGPH
What is the function of this protein?
Involved in spermatogenesis.  Required for sperm head formation but not required to establish and maintain general polarity of the sperm head.  Required for anchoring and organization of the manchette.  Required for targeting of SUN3 and probably SYNE1 through a probable SUN1:SYNE3 LINC complex to the nuclear envelope and involved in accurate posterior sperm head localization of the complex.  May anchor SUN3 the nuclear envelope.  Involved in maintenance of the nuclear envelope integrity.  May assist the organization and assembly of outer dense fibers (ODFs), a specific structure of the sperm tail.
What are the official names of this protein?
Sperm-associated antigen 4 protein, Outer dense fiber-associated protein SPAG4, SUN domain-containing protein 4.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme. Nucleus envelope. Nucleus inner membrane. Note=In spermatids, it is localized in the transient manchette and in the axoneme of elongating spermatids and epididymal sperm (By similarity). Colocalized with SEPT12 at the nuclear periphery in round spermatids, at sperm neck in elongated spermatids and at midpiece regions in ejaculated spermatozoa (PubMed:25775403).
Protein: GPMI_LISW6
Sequence: MSKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWADFPHGELKAAGLDVGLPEGQMGNSEVGHTNIGAGRIVYQSLTRIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDGGVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSSLEYLETLQKAMNDLNYGEIATVSGRFYAMDRDKRWERVEKAYKAIVSAEGEKFEDPIELVKASYANDKNDEFVVPAIITKDGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGANHPKNIKFVTMTLYNPSVDAEVAFEPIEMKNVIGEVLSNEGLSQLRIAETEKYPHVTFFMNGGRNEEFPGENRILINSPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFANPDMVGHSGMLEPTIKAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVKLREGGRLADVAPTMLDLLGVKKPAEMTGESLIQK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: NELFD_HUMAN
Sequence: MAGAVPGAIMDEDYYGSAAEWGDEADGGQQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVAQTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSVSTACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRIAQEVQRFAQEKGHDASQITLALGTAASYPRACQALGAMLSKGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGARINQDHKHKYIHILAYAASVVETWKKNKRVSINKDELKSTSKAVETVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLELKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKTEGEHDPVTEFIAHCKSNFIMVN
What is the function of this protein?
(Microbial infection) The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II.
What are the official names of this protein?
Negative elongation factor C/D, NELF-C/D, TH1-like protein.
What is the protein family that this protein belongs to?
Belongs to the NELF-D family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CNMD_HUMAN
Sequence: MTENSDKVPIALVGPDDVEFCSPPAYATLTVKPSSPARLLKVGAVVLISGAVLLLFGAIGAFYFWKGSDSHIYNVHYTMSINGKLQDGSMEIDAGNNLETFKMGSGAEEAIAVNDFQNGITGIRFAGGEKCYIKAQVKARIPEVGAVTKQSISSKLEGKIMPVKYEENSLIWVAVDQPVKDNSFLSSKVLELCGDLPIFWLKPTYPKEIQRERREVVRKIVPTTTKRPHSGPRSNPGAGRLNNETRPSVQEDSQAFNPDNPYHQQEGESMTFDPRLDHEGICCIECRRSYTHCQKICEPLGGYYPWPYNYQGCRSACRVIMPCSWWVARILGMV
What is the function of this protein?
Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells.  May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development.  Inhibits in vitro tube formation and mobilization of endothelial cells.  Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization.
What are the official names of this protein?
Leukocyte cell-derived chemotaxin 1, Chondromodulin.
What is the protein family that this protein belongs to?
Belongs to the chondromodulin-1 family.
What are the subcellular locations of this protein?
[Chondromodulin-1]: Secreted, extracellular space, extracellular matrix. Note=Accumulated in the inter-territorial matrix of cartilage. SUBCELLULAR LOCATION: [Chondrosurfactant protein]: Endomembrane system; Single-pass membrane protein.