PharMolix/UniProtQA huggingface dataset:
Protein: COX7B_BOVIN
Sequence: MFPLAKNALSRLRVQSIQQAVARQIHQKRAPDFHDKYGNAVLASGATFCVAVWVYMATQIGIEWNPSPVGRVTPKEWREQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix (PubMed:27605664).  Plays a role in proper central nervous system (CNS) development in vertebrates (By similarity).
What are the official names of this protein?
Cytochrome c oxidase subunit 7B, mitochondrial, Cytochrome c oxidase polypeptide VIIb, IHQ.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIb family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: YP78_CAEEL
Sequence: MRRFTLFVFFLSISIAYADFDFEDYNFATFNEIYDNEIPDDIPSSRHFLKSSRGTVGLPKTATEMMTRFNENLLNFLKSKSENDWKLIMELMSPDAFIETCMESAYGLSMDQFHKWITFLSNYYAEVGLTSTKIKDNSETGVTTELVYYTVLRNGEKGSDKWAMSATLNKKKGHFCINTLHMLSECKNIPKKPSLEPAIPIETFISSLKKKLVNDIFLNGGLHYKSAYESMYNYITPATKVFICDVGKMNGNQFVEYWYKRFGKVQTYSEHVFDISNNGTNWHVDFEVTYESEPGKFYRDRYQFSMNKYTNVKVEYFENFLDWRIYQIQQNCTESRTKMSKSDASVVKMALASRRWDQMLNKGLSWDTLQAFKEMFDKSKFHGYTCGMKFENWAKFDNWLTGFSNFYAKSVPKQTNVYAYQDSKIGFWIVNTMSAASDNSTSTHRVFFEGYYVC
What are the official names of this protein?
Uncharacterized protein B0228.8.
Protein: DAPE_XYLFA
Sequence: MSEVFDLTCDLISRPSVTPEDAGCQAMIAARLERVGFTCEHLHYGSVANLWATHGQGAPVLVLLGHTDVVPPGPIEAWTSDPFIPQRREGKLYGRGAADMKGSVAAFVIAAERFLVAHAGHPGTLAILLTSDEEGQAIDGVRKVAETLRQRGQGIDWCLTGEPSSSKRLGDLLRVGRRGSLSATLHVKGVQGHVAYPHQARNPIHLAVPALAALTARHWDDGDESFPSTSLQISNIHAGTGANNVIPGALEVAFNLRYNPHWSAPRLESEIVALLDQHGLDYTLHWHRSGEPFYTPEGKLRRIAREVLERFSGAPPEESTGGGTSDARFIAPLGAQCIEIGPVNASIHQVDEHVCLADLEALPDLYQLLIERLLADH
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: UCHL3_BOVIN
Sequence: MEGQRWLPLEANPEVTNQFLKQLGLHPNWQFVDVYGMDPELLSMVPRPVCAVLLLFPITEKYEVFRTEEEEKIKSQGQDVTSSVYFMKQTISNACGTIGLIHAIANNKDKMHFESGSTLKKFLEESASMSPEERARYLENYDAIRVTHETSAHEGQTEAPNIDEKVDLHFIALVHVDGHLYELDGRKPFPINHGETSDETLLEDAIEVCKKFMERDPDELRFNAIALSAA
What is the function of this protein?
Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins.  Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8.  Has a 10-fold preference for Arg and Lys at position P3''.  Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling.  Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis.  Required for stress-response retinal, skeletal muscle and germ cell maintenance.  May be involved in working memory.  Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase isozyme L3, UCH-L3, Ubiquitin thioesterase L3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_BART1
Sequence: MTSKTVTRADLASVVCKKVGLSHTESAALVELVLDEICNSLVRGEAVKLSSFATFQVRSKNERIGRNPKTGVEAPIPPRRVVTFKAANILKQRILDSHRAKQKKDLL
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NUOF_BUCBP
Sequence: MKKLLSRTSETHPLTWRLNAQQDTVWIKEYKRKNGYRAFEKVVNHMTSEDVIDLIKQSGLKGRGGAGFLTGLKWSLMPPLNDEYGYTRYLLCNADEMEPGTYKDRFLMEKVPHQLLEGILISAFALSVTKSYIFLRGEYVNTERILKQSIIEATNYGYLGKNVCGSNLTFEIFIHTGAGRYICGEETALINSLEGRRANPRFKPPFPAYVGLWGKPTCVNNVETLSNVPAIFLNGVKWYKGLSKSLDTGTKMMGFSGSVKFPGIWELPFGITAREIFERYAGGMKNNKKLKVWQPGGASTSFLIDKHLDVPMDFVNIKKVGSRLGTALAMAVDDSVSIVSLVRNIEEFFSRESCGFCTPCRDGLPWIVKILKVLEQKIGVPEDIEILEQLCEQLGPGRTFCAHAPGAIEPLKSALKYFRLEFELCVNSNSTIKCKYIHSSISEY
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit F, NADH dehydrogenase I subunit F, NDH-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
Protein: SL9B2_TRIST
Sequence: MGRLIFVSFGLLVVFLSLSGTAADCLSGWSSYEGHCYKPFNELKNWADAENFCTQQHAGGHLVSFQSSEEADFVVKLAFETFGHSIFWMGLSNVWNQCNWQWSNAAMLRYKAWAEESYCVYFKSTNNKWRSRSCRMMANFVCEFQV
What is the function of this protein?
Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factors IX (F9) and factor X (F10) in the presence of calcium with a 1 to 1 stoichiometry.
What are the official names of this protein?
Snaclec coagulation factor IX/factor X-binding protein subunit B2, IX/X-bp subunit B2.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: PALI2_KLULA
Sequence: MLVKIVLVVLLTLALVFECFSTISVPITIGLYISEYNGYRFGVFGWCKVDRSVCSPIRIGYSKDDILLFNEQEYLHLPNHAKYALSNLLLVHVLAFVCVTILWVFGMLTCFRCIKTSRRMLIIAVLWSMLTFMVTLLGFLIDILIFSSHVTWCTWLTLASAFFTVLSGTVLCVMRRNLTYDKFLESKPEKHGVYVPLCRLNDVEELEIPWCNTMNHQALTAPTPM
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator palI/RIM9 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the palI/RIM9 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLGB_PROM3
Sequence: MTTSVALDWVVQDGQRLAECRHDHPFSLLGPQSHEGQWIVRIWMPEASQVELLCDGRTTAMTTPNHSWIFEAALNQDPGRTYQLRVKRAGIVHEQHDPWAFHDEWMGEMDRHLFAEGNHHHIWQRMGAHLMEREGVEGVMFCLWAPRACSVAVLGELNGWDGRHHPMQRRQGGLWELFIPGFKEGTLYKYEIRTQDGHCYQKADPYGFQHEVRPATSSVVARLDRYQWQDEQWMRQRDSRNALDQPISVYEMHLGSWIHAATDEPYIELDGTPRAPVLAADMKPGARLLTYPELADQLIPYVKDRGFTHIELMPISEHPFDGSWGYQVTGWYAPTSRFGSPDEFRAFVDRCHAEGLGVIIDWVPGHFPKDGHGLAFFDGTHLYEHSDPRIGEHKEWGTLIFNYSRNEVRNFLVANLVYWFEQFHIDGIRVDAVASMLYRDYLRPDGEWIANEDGGRENTEAVRFLQQANHVLFQHFPGALSIAEESTTWPMVTQPTDMGGLGFNLKWNMGWMHDMLDYFELDPWFRQFHQNNITFSIWYTYTENFMLALSHDEVVHGKSNLLHKMPGDDWQKCANVRALLAYMWTHPGKKTIFMGMEFGQRSEWNVWGDLQWELLTHDPHKGLQKLVDDLNTFYKAEPALWKDDFDQYGFQWIDCNDNRHSIISFMRRESSGGTWLVVVANFTPQSHSNYRIGVPIGGYYEEVFNTDSSCYGGRNLGNMGGKNTDEFNIHGYEQSLELCLPALSVLVFRHDPKRSL
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: BIG2_ARATH
Sequence: MASSEADSRLSRVVTPALEKIVKNASWRKHSKLANECKAVIERLNSLQKSPPPSSSAATDSESESSVPGPLNDGGSIEYSLADSELIFSPLINACGTGLAKIIEPAIDCIQKLIAHGYIRGESDPSGGAESLLLFKLIDSVCKCHDLGDESIELPVLKTLLSAINSISLRIHGKCLLLVVRTCYDIYLGSKNVVNQTTAKASLIQILVIVFRRMEADSSTVPIQPIVVAELMEPLEKSDADGTMTQFVQGFITKIMQDIDGVLNPTMSGSGSGSGSGGQDGAYGTTTVETTNPTDLLDSTDKDMLDAKYWEISMYKSALEGRKGELTDGDAERDDDLEVQIENKLRRDACLVFRALCKLSMKAPPKESSADPQSMRGKILALELLKILLENAGAVFRTSEKFSADIKQFLCLSLLKNSASTLMIIFQLSCSIFISLVARFRAGLKAEIGVFFPMIVLRVVENVAQPNFQQKMIVLRFLDKLCLDSQILVDIFLNYDCDVNSSNIFERMVNGLLKTAQGVPPGTATTLMPPQEAAMKLEAMKCLVAILKSMGDWLNKQLRLPVSNSLNKSDVIEIDLGPGSPQLANGNADESADGSDTYSESSGGTSDALAIEQRRAYKLELQEGISLFNRKPTKGIEFLINAGKVGESPEEIAGFLKDASGLNKTLIGDYLGEREDLALKVMHAYVDSFDFRGMEFDEAIRTFLEGFRLPGEAQKIDRIMEKFAERYCKCNPKVFTSADSAYVLAYSVIMLNTDAHNPMVKNKMSADDFIRNNRGIDDGKDLPADYMRSLYERITKHEIKMKEDDLRLQQKQYANSNRMLGLDGILNIVIRKQWGDSYAETSDDLMKHMQEQFKEKARKSESTYYAATDVVILRFMIEACWAPMLAAFSVPLDQSDDLIVINICLEGFHHAIHATSLMSMKTHRDAFVTSLAKFTSLHSPADIKQRNIEAIKAILRLADEEGNYLQDAWEHILTCVSRFEQLHLLGEGAPPDATFFASKQNESEKSKQPKQYILPVLKRKGPGKSQYAATGVLRGSYDSMSLGGKGSKNVRQEQMSSIVSNLNLLEQVGEMNQVFSQSQKLNSEAIIDFVKALCKVSMDELRSPSNPRVFSLTKIVEIAHYNMNRIRLVWSSIWQVLSGFFVTIGCSENLSIAIFAMDSLRQLSMKFLEREELANYNFQNEFMTPFVIVMRRSNDVEIRELIIRCVSQMVLSRVNNVKSGWKSMFMVFTTAAYDDHKNIVFLSFEIIEKIIREYFPYITETETTTFTDCVNCLVAFTNNRFSKDISLSSIAFLRYCATKLAEGDLNSPSTNKYKGTSGKIPQSSLHSGKSGKQENGEIVNNNHLYFWFPLLSGLSELSFDPRPEIRKSALQIMFDTLRNHGHLFSLPLWEKVFESVLFPIFDYVRHSIDPSGEDESADQGSSGGEVDELDHDAWLYETCTLALQLVVDLFVKFYTTVNPLLEKVLMLLVSFIKRPHQSLAGIGIAAFVRLMSDADGLFSEEKWLEVVSALKEAAKTTCPDFSYFLSEEYVARSQRSALNIQNSNAESAAPTATDGNEESQRTATHLYAAISDAKCRAAVQLLLIQAVMEIYNMYRPQLSAKNTLVLVDALHGVALHAHGINSNTILRSRLQELGPMTQMQDPPLLRLENESYQICLTFLQNLVADKTKKEEEEEEEEIESLLVNICQEVLNFYIETSSSAKKLQSESSRASEYRWRIPLGSGKRRELSARAPLIVATLQAMCTLDEASFEKNLKCLFPLLANLISCEHGSNEVQTALADMLGLSVGPVLLQWC
What is the function of this protein?
Activates the ARF proteins by exchanging bound GDP for free GTP.  Plays a role in vesicular protein sorting (By similarity).
What are the official names of this protein?
Brefeldin A-inhibited guanine nucleotide-exchange protein 2, BIG2, ARF guanine-nucleotide exchange factor BIG2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Note=Soluble and partially membrane-bound.
Protein: WEE2_CANLF
Sequence: MDDSSINKELKQKLNVSYCEEESESEGQKEAPESRETQSQTPDWAEGQESEAKFTPPRTPSSSIHGVGTFEEKDKMSPDQALRTPGPGFHKCPGTPAQPDSRSEVVHCESPYTPKSLLSQSVISSTEKLPSRGSKHLRFTPVPFVDEMTSSALVNINPFTPESYRKQFLRSNGKRKTRGDLEEADPGEGKVEQGLPAKRCVLRETNMASRYEKEFLEVEKIGVGEFGTVYKCIKRLDGCVYAIKRSMKPVAGLSNENLALHEVYAHAVLGHHPHVVRYYSAWAEDDHMIIQNEYCNGGSLQTAISENTKSGNHFPELKLKDILLQISLGLKYIHNSGMVHLDIKPSNIFICHKMQCDSPVVPEEIENEADWFLSANVMYKIAGDLGHVTSISKPKVEEGDSRFLANEILQEDYQHLPKADIFALGLTIAVAAGAESLPANGAKWHHIREGNLPDIPQKLSEEFHNLLKNMIHPDPSERPSAAGLARSRVLRPSLRKAEELQQQLNLEKSKTATLERELREAQQAWSPQEEHSDPGVSGTPTGSRCTKRPVGGKSAKSSSFTCGKSSP
What is the function of this protein?
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II.  Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry.  Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
What are the official names of this protein?
Wee1-like protein kinase 2, Wee1-like protein kinase 1B, Wee1B kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAPC_ASPCL
Sequence: MQPTLAPAPHPSMQTSAQDHADQVLHDQLLAAHQHLSHPQQARPPPPPPQPPHMQPTTPVARDQNNIDPAISGGAMLAGPQTPQPDLSGQESPKTYGKRPLSTSKRAAQNRAAQRAFRQRKEAHIRDLEGKVKAYETMGEAIKALQAENYQLREYIINLQSRLLDTQGEVPELPGNIDLSQPRGDIPVPAPPTSGTSTSAVPVPPPTAPQQPQPAQNQASAPNDDMNSLNRIAVAGLGMRKPPTEEANYLGNSFQQQARRVRPDDGQPDASELTLPKQEPTHGLPLIS
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Putative transcription factor kapC.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL29_STRA1
Sequence: MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQLEKTARLDEVKKQIARVKTVQSEMK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TILS_RICRO
Sequence: MLYEKFEYNINNLIGNFSLSKISIAVSGGSDSVALLYLANIWAEKNNIELFVISVDHNLREQSKQETHYIQNISNSLNRKHYSLSFDHQNNFSNLQERAREGRYDLMTNLCLELDILVLLTAHHEDDYVENFCLRLERNSGIFGLSSSNINWYNNIHIIRPLYNIPKSELVEYLVSHNIKWFEDESNSSDKYRRNVIRQKLAKGADYIRHFSKPVYREEFKGDTERSTAAYTSVREDASTGTASKLSLEAKCGKMSKAAIISQQLKTNKRIENEFKPELISAIAEAVKIFEYGFAFLDLVKFDKFSNEVKVQIINFLLIIISGQSRAARFYSVEPILKLITQDVNFKNTLHGCIIKRIQNELLIYREFGKKLPESKILLDKSVIWDNRFCITKNQEAPNCFVTHLSLKDYKIIKKQLDLEPLKNLSCKNHNAVLLTLPIIKILEKVIAIPHISYYDNDMWNFEVSFSPNFVSRFTHFC
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_RICTY
Sequence: MTKNPKISLIGSGNIGGTLAHLISLKKLGDIVLFDVAEGVPQGKALDIMQAATIAGADIKIKGTNNYKDIEGSDAVIITAGLPRKPGMSRDDLISVNTKIMQDVAQNIKKYARNAFVIVITNPLDIMVYVMLKESGLPHNKVIGMAGVLDSSRFNLFLAEEFKVSVRNVNSIVLGGHGDAMVPLVRYSTISGVPIPDLIKMGLSSNKNIEKIIDRTRNGGGEIVALLKTGSAYYAPAASAIAMLESYLKDKRQILTCAAYLQGEYDVHDLYIGVPIIIGKEGVIKVIELQLTEEEKILFDKSVVGVKKLIDAIQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: IDH3B_PIG
Sequence: ASRSQAEDVRVEGAFPVTMLPGDGVGPELMAAVGVIECLKLGDGLFLQCCEEVAELYPKNIANPTATLLASCMMLDHLKTSDMGGYATCQDFTEAVIGALSHP
What is the function of this protein?
Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate.  The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
What are the official names of this protein?
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta, NAD(+)-specific ICDH subunit beta.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RRP3_PORPU
Sequence: MSKFTLKVLWLENNIAIAIDQIVGNGTSPLTSYFFWPRNDAWEELKAELESKPWIAERDRIELLNKTTEVINYWQEEGKKHSLSKAQARFPEFIFSGSN
What is the function of this protein?
Probably a ribosomal protein or a ribosome-associated protein.
What are the official names of this protein?
Probable 30S ribosomal protein 3, chloroplastic, PSRP-3.
What is the protein family that this protein belongs to?
Belongs to the chloroplast-specific ribosomal protein cS23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL18_TERTT
Sequence: MNAKKQSRIRRATRSRSKIRELRETRLCVNRTPRHIYAQIISPESDKVLASASTLDKDLRSGATGNIDAATAVGKLIAERAKAAGVTKVAFDRSGFKFHGRVKALADAARESGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: IBBB4_HYAOR
Sequence: GQQPLCNDCFACARSLCICGDLVPQCHEGCQQCEKVDTLSGKPLYQCRSFEDYQCAN
What is the function of this protein?
Serine protease inhibitor (PubMed:33666645).  Inhibits trypsin (Ki = 110 nM) and very weakly inhibits chymotrypsin (Ki =1200 nM) (PubMed:33666645).  Does not inhibit bacterial subtilisin (PubMed:33666645).
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor B4, HOSPI-B4.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: PYRDB_GEOSW
Sequence: MNRLAVELPGLSLKNPIMPASGCFGFGREYAQFYDLSKLGAIMIKATTKEPRFGNPTPRVAETPGGMLNAIGLQNPGLQKVLEEELPWLAQFDVPIIANVAGSTMEEYVEVAKHISKAPNVHALELNISCPNVKKGGIAFGTVPEIAAELTKLVKEVSEVPVYVKLSPNVTNIVEMAKAIEAAGADGLTMINTLLGMRIDVKTAKPILANRTGGLSGPAIKPIAIRMIYEVSQAVSIPIIGMGGIQSAEDVIEFFYAGASAVAIGTANFIDPFVCPNIIAELPVLLDELGIDHISECMGRSWKKGERSVYCGA
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLU5D_COLGM
Sequence: MQIQNLIAALAGMAVVAEASVTFLDSPLSAALAKRQNKGGNNNNNNNNNNNNNNNNNKNNGGNNQLCLNPNNVQKGSQQAGTPKQGQANSAVDQANFINFCTGQQLTNGEQKTAGSCNGVVMGKIPSQNNMVSTIIKNPPPGGNLQANQQFNVQLKVNNLQAGSFTDAQSTYYSAPQDTNGAGNIIGHVHVTIQDMGNSLTPQNALDPKQFVFFKGIDDAGDGKGNLQATVTGGLPAGNYRVCTMSSASNHQPVLMPVAQRGAQDDCNKFTVGGNGGNGGNGGNGGNGGNGGNGGNGGNGGKNAAVNSGNADNGGNNDGGGGGNDGGNNSANNSGSGNKQGGKQQNGASTGGFPGTSNQFPGKTGTGSGAQTGNANTKTQAGGSASNSATNGNSGTGGKGGATANAIGGIQAPAVTNSGDSSRPFAVNGNTFVNKAAAVQRACDIQRNGCFDAINRGKLTGSTADCDAQLQTCTQQLS
What is the function of this protein?
Secreted protein required for appressorial penetration of intact host epidermal cells and for pathogenicit, but not for subsequent biotrophic and necrotrophic colonization of leaves.
What are the official names of this protein?
Pathogenicity cluster 5 protein d.
What are the subcellular locations of this protein?
Secreted.
Protein: TRUA_STRS2
Sequence: MTRYKAIISYDGHDFSGFQRQPHARTVQEEIEKTLVRLNSGQPVTVHGAGRTDAGVHAYGQVIHFDLAGSRDVEKLRFALDTQTSEDIDVVSVEQVADDFHCRYAKHSKTYEFLVDIGRPKNPMMRHYATFYPYDLDLSLIEEAIQDLVGTHDFTGFTASGTSVEDKVRTITVASMEYDQQRQFLIFTFSGNGFLYKQVRNMVGTLLKIGNGRMPVGQIKRILAEKDRGLAGPTAAGNGLYLKEIIYED
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: AGRA2_MOUSE
Sequence: MGAGGRRMPVPPARLLLLPLLPCLLLLAPGTRGAPGCPVPIRGCKCSGERPKGLSGGAHNPARRRVVCGGGDLPEPPDPGLLPNGTITLLLSNNKITGLRNGSFLGLSLLEKLDLRSNVISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFQGLPRLLRLNISGNIYSSLQPGVFDELPALKIVDFGTEFLTCDCRLRWLLPWARNHSLQLSERTLCAYPSALHAHALSSLQESQLRCEGALELHTHYLIPSLRQVVFQGDRLPFQCSASYLGNDTRIHWYHNGAPMESDEQAGIVLAENLIHDCTFITSELTLSHIGVWASGEWECSVSTVQGNTSKKVEIVVLETSASYCPAERVTNNRGDFRWPRTLAGITAYQSCLQYPFTSVPLSGGAPGTRASRRCDRAGRWEPGDYSHCLYTNDITRVLYTFVLMPINASNALTLAHQLRVYTAEAASFSDMMDVVYVAQMIQKFLGYVDQIKELVEVMVDMASNLMLVDEHLLWLAQREDKACSGIVGALERIGGAALSPHAQHISVNSRNVALEAYLIKPHSYVGLTCTAFQRREVGVSGAQPSSVGQDAPVEPEPLADQQLRFRCTTGRPNISLSSFHIKNSVALASIQLPPSLFSTLPAALAPPVPPDCTLQLLVFRNGRLFRSHGNNTSRPGAAGPGKRRGVATPVIFAGTSGCGVGNLTEPVAVSLRHWAEGADPMAAWWNQDGPGGWSSEGCRLRYSQPNVSSLYCQHLGNVAVLMELNAFPREAGGSGAGLHPVVYPCTALLLLCLFSTIITYILNHSSIHVSRKGWHMLLNLCFHMAMTSAVFVGGVTLTNYQMVCQAVGITLHYSSLSSLLWMGVKARVLHKELSWRAPPLEEGEAAPPGPRPMLRFYLIAGGIPLIICGITAAVNIHNYRDHSPYCWLVWRPSLGAFYIPVALILPITWIYFLCAGLHLRSHVAQNPKQGNRISLEPGEELRGSTRLRSSGVLLNDSGSLLATVSAGVGTPAPPEDGDGVYSPGVQLGALMTTHFLYLAMWACGALAVSQRWLPRVVCSCLYGVAASALGLFVFTHHCARRRDVRASWRACCPPASPSASHVPARALPTATEDGSPVLGEGPASLKSSPSGSSGRAPPPPCKLTNLQVAQSQVCEASVAARGDGEPEPTGSRGSLAPRHHNNLHHGRRVHKSRAKGHRAGETGGKSRLKALRAGTSPGAPELLSSESGSLHNSPSDSYPGSSRNSPGDGLPLEGEPMLTPSEGSDTSAAPIAETGRPGQRRSASRDNLKGSGSALERESKRRSYPLNTTSLNGAPKGGKYEDASVTGAEAIAGGSMKTGLWKSETTV
What is the function of this protein?
Endothelial receptor which functions together with RECK to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B) (PubMed:25373781, PubMed:25558062, PubMed:28803732).  Plays a key role in Wnt7-specific responses, such as endothelial cell sprouting and migration in the forebrain and neural tube, and establishment of the blood-brain barrier (PubMed:21071672, PubMed:21282641, PubMed:21421844, PubMed:25373781, PubMed:28288111).  Acts as a Wnt7-specific coactivator of canonical Wnt signaling: required to deliver RECK-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex (By similarity).  ADGRA2-tethering function does not rely on its G-protein coupled receptor (GPCR) structure but instead on its combined capacity to interact with RECK extracellularly and recruit the Dishevelled scaffolding protein intracellularly (By similarity).  Binds to the glycosaminoglycans heparin, heparin sulfate, chondroitin sulfate and dermatan sulfate (By similarity).
What are the official names of this protein?
Adhesion G protein-coupled receptor A2, G-protein coupled receptor 124, Tumor endothelial marker 5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, filopodium. Note=Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact.
Protein: HES7_MOUSE
Sequence: MVTRERAENRDGPKMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAVGYLRERSRVEPPGVPRSPGQDAEALASCYLSGFRECLLRLAAFAHDASPAARSQLFSALHGYRRPKPPRPEAVDPGLPAPRPPLDPASPILGPALHQRPPVHQGPPSPRLAWSPSHCSSRAGDSGAPAPLTGLLPPPPPPYRQDGAPKAPSLPPPAFWRPWP
What is the function of this protein?
Transcriptional repressor.  Represses transcription from both N box- and E box-containing promoters.  May with HES1, cooperatively regulate somite formation in the presomitic mesoderm (PSM).  May function as a segmentation clock, which is essential for coordinated somite segmentation.
What are the official names of this protein?
Transcription factor HES-7, mHes7, Hairy and enhancer of split 7, bHLH factor Hes7.
What are the subcellular locations of this protein?
Nucleus.