PharMolix/UniProtQA huggingface dataset:
Protein: SPRTN_CAEEL
Sequence: MSRSSLVDPSFELSDPCPDIHALFIQFDARFFGGSLACCEVKWSPRMYACAGICSYEIRGGRGGLCSIRLSKPLLTLRPRSDLVETLLHEMIHAYLFVKERNRDRDGHGPQFQAHMHRINQAGGTNITIYHSFHDEVRLYKQHWWRCSGPCRDRRPFFGYVKRSCNRAPGPNDRWWSQHQQSCGGNFLKVKEPEGYGQGKGSKRTNDKNKSGGPALKKTITPPRVTLDDFFKKDGKNSSDNSTSKSPTKPSTSLFTGSGQKLGGSSSTSSLLNSYPKATQNSGGNRLGGTSGGVSRLLPPVNFTSPSSAPVAEQVIDLGDSDDDDFQDMDDDALEISFVASDNSVICPSCNTEVMENLIHGHLDYCLG
What is the function of this protein?
DNA-dependent metalloendopeptidase that mediates the proteolytic cleavage of covalent DNA-protein cross-links (DPCs) during DNA synthesis, thereby playing a key role in maintaining genomic integrity (PubMed:27871365).  DPCs are highly toxic DNA lesions that interfere with essential chromatin transactions, such as replication and transcription, and which are induced by reactive agents, such as UV light or formaldehyde (PubMed:27871365).  Associates with the DNA replication machinery and specifically removes DPCs during DNA synthesis (PubMed:27871365).  Regulator of UV-induced DNA damage response: required to protect genome stability during DNA replication, possibly via recruitment of vcp/p97 (cdc-48. 1 or cdc-48. 2) recruitment (PubMed:23042605).
What are the official names of this protein?
DNA-dependent metalloprotease dvc-1, DNA damage protein targeting VCP, DVC1, Protein with SprT-like domain at the N terminus, Spartan.
What is the protein family that this protein belongs to?
Belongs to the Spartan family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to nuclear foci following UV treatment.
Protein: RS11_PSELT
Sequence: MARRSEGKKKRKILTDRGVVHIKSTFNNTVITLSDADGATILWSSGGTAGFEGTRKGTPYAAQLAADKIAKEALRLGIKRVDVLVKGPGPGREAAIRTLQAAGLEVDSIKDVTPIPFNGCRPKKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL30_EUPES
Sequence: MVAAKKTKKTHESINSRLALVMKSGKFTLGYKTVLESLRSNKGKLIIIANNCPPLRKSEIEYYAMLAKVGVHHYNGNNVDLGTACGKYFRVCCLSIIDAGDSDIIKSIPGDH
What are the official names of this protein?
60S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL30 family.
Protein: TPZ1_SCHPO
Sequence: MSNCLKHPWLENGLLNLIKNADVLPIRVFKCQPLQIFEYIRYEHPIRCKLSDTEFYIEAEFSSQSISDLNNFTEKRITSLRGGIVTLGNFLIHLIPSQSGIIPWIQVESFNFQGCEGAVFGNPKAITTSALFNALLQSPYLAALANEFNRSIKEGSSYQEASLSQQEKPNDNTSNSRDIKNNIQFHWKNMTSLSIEECIIPKGQQLILEKESEENTTHGIYLEERKMAQGLHNSVSETPEVKQEDNDEDLDAYSWSSSTDSAGEIPSLPTNRKILEKIAEKPPPFESPLEDDETPDQTNEHEANQVNVSQLPLNPRGSGISGRPVESTEQLNSSLTIERSQSIQSTDSKQRVETQSHRRSKIEIFDAQDELFDRSICTTIDDSTGKLLNAEETPIKTGDLHSTSASSVISCTPPAINFTSDICNEQIELEYKRKPIPDYDFMKGLETTLQELYVEHQSKKRRLELFQLTNNHQKNSEACEMCRLGLPHGSFFELLRDWKKIEEFRNKS
What is the function of this protein?
Telomeric DNA-binding protein that is required to protect the 3'-end telomeric overhang and involved in telomere length regulation.  recruits poz1 and ccq1 to telomeres, regulating telomere length negatively and positively respectively.
What are the official names of this protein?
Protection of telomeres protein tpz1, Meiotically up-regulated gene 169 protein.
Protein: NADA_HELPH
Sequence: MPTDNDLKTSIVELLHDLDALLVAHFYQKDEIVELAHHTGDSLELAKIASQSDKNLIVFCGVHFMGESVKALAFEKQVIMPKLSCCSMARMIDSHYYDRSVHLLKECGVKEFYPITYINSNAEVKAKVAKDGGVVCTSRNASKIFNHALKQNKKIFFLPDKCLGENLALENGLKSAILGVNSPEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNADFSGSTSQIIEFVEKLSPNQKVAIGTESHLVNRLKAKRHHQNTFILSSTLAFCPTMNETTLKDLFEVLKAYKNHRAYNAVELKDEVAHWAKLALTKMMELS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_CHLAB
Sequence: MIKLESLQDPSPRKRRTKLLGRGPSSGHGKTSCRGHKGDGSRSGYKRRFGYEGGGVPLYRRVPTRGFSHARFDKCVEEITTQRLNALFSEGEEITLEALKQKKAIDKRAIRVKVIVKGDLEKTFIWKDANVVLSQGVRNLIGVA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RL15_BURM1
Sequence: MELNNLKPAAGAKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFTSLTKEFVGEVRLGDLEKLPVDEIDLLALKQAGLVGELTKSAKIIATGELKRKIVVKGLGATKSARAAIEAAGGSFAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RBL_SYNPW
Sequence: MSKKYDAGVKEYRDTYWTPDYVPLDTDLLACFKCTGQEGVPKEEVAAAVAAESSTGTWSTVWSELLTDLDFYKGRCYRIEDVPGDKESFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPMAFIKSCYGPPNGIQVERDRMNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDFTKDDENINSQPFQRWQNRFEFVAEAIKLSEQETGERKGHYLNVTANTPEEMYERAEFAKELGMPIIMHDFITGGFTANTGLSKWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDQLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALVTIFGDDSVLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGRHLEKESRDILMEAGKHSPELAIALETWKEIKFEFDTVDKLDVQN
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: UCR11_SOLTU
Sequence: MTSPAAAGNGLFKFLRPKLRPQSTDIQAAAGWGVAAVTGALWVIQPWDFLRKTFIEKQEEEK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.  QCR10 has a role in CIII assembly and RIP1 stability.
What are the official names of this protein?
Ubiquinol-cytochrome c reductase complex 6.7 kDa protein, CR6.
What is the protein family that this protein belongs to?
Belongs to the UQCR11/QCR10 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RS2_CLOD6
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQKTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLTNHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGAMFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMATAVIEGRQGAEEEVAEDQE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PROB_VARPS
Sequence: MTSNSGSTALRDARRIVVKVGSSLVTNEGRGLDEAAIGEWCRQLAVLVQGGREVVMVSSGAIAEGMKRLGWRTRPHEVHELQAAAAVGQMGLAQMYETKLRENRIGSAQVLLTHADLADRERYLNARSTLVTLLGLGVVPVINENDTVVNDEIKFGDNDTLGALVANLVEADALVILTDQKGLYTADPRKDPQAKFVHEAAAGDPALEAMAGGAGSSLGRGGMITKILAAKRAAGSGASTVIAWGREPDALLRLVRGESIGTLLVAQTAKHQARKRWMADHLQLRGAVTVDAGAAAKVRAEGKSLLPIGMTGVSGEFSRGDVIAVRDADGVELARGLANYSSVEARLLCRKPSSEFERLLGYVAEPEMVHRDNMVLMRG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U17LC_MOUSE
Sequence: MVVSLSFPEADPALSSPGAQQLHQDEAQVVVELTANDKPSLSWECPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEYSQTCCSPEGCKMCAMEAHVTQSLLHSHSGDVMKPSQILTSAFHKHQQEDAHEFLMFTLETMHESCLQVHRQSEPTSEDSSPIHDIFGGLWRSQIKCLHCQGTSDTYDRFLDVPLDISSAQSVNQALWDTEKSEELRGENAYYCGRCRQKMPASKTLHIHSAPKVLLLVLKRFSAFMGNKLDRKVSYPEFLDLKPYLSQPTGGPLPYALYAVLVHEGATCHSGHYFSYVKARHGAWYKMDDTKVTSCDVTSVLNENAYVLFYVQQTDLKQVSIDMPEGRVHEVLDPEYQLKKSRRKKHKKKSPCTEDAGEPCKNREKRATKETSLGEGKVLQEKNHKKAGQKHENTKLVPQEQNHQKLGQKHRINEILPQEQNHQKAGQSLRNTEGELDLPADAIVIHLLRSTENWGRDAPDKENQPWHNADRLLTSQDPVNTGQLCRQEGRRRSKKGKNKNKQGQRLLLVC
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes (PubMed:8995226, PubMed:11443643).  Important for preimplantation stage embryonic development (PubMed:22984479).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein C, Deubiquitinating enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: MURI_BRUA1
Sequence: MKKAPAGSFPAKPTIAPERPILVFDSGIGGLTVLREARVVMPDRRFVYIADDAGFPYGNWEEEALKRRIIELFGEFIANYDPEIAVIACNTASTLVLEDLRRAYPSVPFVGTVPAIKPAAERTSSGLVSVLATPGTVKRAYTRDLIQSFASRCHVRLVGADGLAAIAEAHIRGESFDEALVMAQIAPCFIEKDGKRTDIVVLACTHYPFLVNVLRRLAPWPVDWLDPAEAIARRMKSLLPARSDDDEFHSQDDLAFFTSRKPDYAIRRLMQGFGLRF
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: YBHA_ECOLI
Sequence: MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
What is the function of this protein?
Catalyzes the dephosphorylation of pyridoxal-phosphate (PLP).  Can also hydrolyze erythrose-4-phosphate (Ery4P) and fructose-1,6-bis-phosphate (Fru1,6bisP).
What are the official names of this protein?
Pyridoxal phosphate phosphatase YbhA, PLP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: DCD_THISH
Sequence: MSIKSDRWIRRMAEQHGMIEPFEPGQVRHAGEERIVSYGTSSYGYDVRCADEFKIFTNINSSIVDPKAFDARSFVDVKSDVCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTPLPAKIYANEGVAQMLFLESDEVCETSYKDRGGKYQGQVGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: PENK_CAVPO
Sequence: MARLLRLCTWLVALGPGLLATVQAECSQDCAACSYRLVRPGDLNFLACTLECEGQLPSLKIWETCKDLLQVSKQELPQEGASSLRESGKQDESHLLSKKYGGFMKRYGGFMKKVDELYPVEPEEEANGGEILTKRYGGFMKKDAEDGDALANSSDLLKELLGTGDDRDRENHHQEGGDSDEGVSKRYGGFMRGLKRSPQVEDEAKELQKRYGGFMRRVGRPEWWMDYQKRYGGFLKRFAEFLPSDEEGESYSKEVPEMEKRYGGFMRF
What is the function of this protein?
Increases glutamate release in the striatum.
What are the official names of this protein?
Proenkephalin-A.
What is the protein family that this protein belongs to?
Belongs to the opioid neuropeptide precursor family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, chromaffin granule lumen. Secreted.
Protein: MDTC_ECOHS
Sequence: MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFTVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRHPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL20_BRASB
Sequence: MSRVKRGVTAHAKHKKVFKAAKGYYGRRKNTIRTAKQAVEKAGQYAFRDRKRKKRTFRALWIQRLNAAVRPFELTYSRFIDGLSKSGITVDRKVLSDLAINEPAAFQAIVEKAKAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: GPTC1_CAEEL
Sequence: MNRKKLAAYGQEFEDDDEEGSSVSKKPTQIHEEIATDEKGKRRFHGAFTGGFSAGYWNTVGSKQGWVPQVFSSSRNERGEQIKQRAEDFMDAEDLGEYGIGNRSIKQTAAFGEGAGQKRKMAWERDTTSISTITQMFEDVVKPVSNSIGVRMLRSMGWREGRGIGLANVKQKQKRGGESSEAQFDREQASKVAPAYEFSNEDALVKQLTPLTGTHGIGYQGLRKTTVLNESYGRTTLALKSGKKNSKGIKGQAFGVGAFEEEDESVYSNYDLSQFDFSLDVAGASEESNLKTQKLVTAFELQPKRLNPRKFYAPPRVPPNFRGDHRPIPMDISKLPQMMKNDVKHMNAEQRAKFLGEDRVNALEIGGKSSKKPTERRSRWDIKANEVEKRDNERGGGEAEEDRDRRQRNRIEFPDEPMRQARFKEFLHYIRRGLPYPQPTDLTVWEWEWEKKEFESKLTSDERGMLPEVQSRAQPLAKTAIAAPIHEMMASKFVKEAGGDLKVGTKDEDKLAAVKMEMFGEKTRQSFDWYPDNLLAKRFNVPHPYPGSDTVGVPALQKTDWKRKDRLADIGGVSATLGLPNTANEIEMRERLLKSRAQRGAEEKKRNQSDDDDEKEYDDKDSDEEEENEAEPNNQKVDKAPKSFFDFIFGDGDGADSDESNSEDEEAEEKERQEILKKREEDLKRRREIVEKKEEENRKRVEKELKELENRDLLRVSKQQEDDDIQIIDETSASSFGPALPPSSKPVLSKTEVLKLLEKNMKKKKKDKKEKEKKKKSKKSKKSKKEKKTKRKHSSSSADDSGDNSDGWEEKK
What are the official names of this protein?
G patch domain-containing protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the GPATCH1 family.
Protein: CA17_CONLE
Sequence: MGMRMMFTMFLLVVLTTTVVSFNSDRESNHENRRTSNQITRGMWDECCDDPPCRQNNMEHCPAS
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Lp1.7, Alpha-conotoxin-like Lp1.8.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YJIH_ECOLI
Sequence: MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWRVFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDGLGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKVIFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEERRNPTQGAQA
What are the official names of this protein?
Uncharacterized protein YjiH.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PEX16_XENTR
Sequence: MAARYWDKLQDLSQKYKDYVIQNPTGATQLESAVRMLSYLIAGRFADSHELSELVYSASNLLALLNDGILRKELLAPPPTEGSRRRLLTWLGVLESLEVFIEIGAARAWGDRTRWAAILIIQLLKACLRIVLLFWYRAGIQSSPPVTPLDREGILNQAEDNSNSGSSCFVGRRSSRAVRSLDDSASSHRRFWRSPQIHDGKQRNTGETESDKDGSELGTLGTLAEAIHILRPITHLLSLATWGQKSWKPWMVAAALDITSISLLSDVRNLSHRERAELRRRMFLLLYYLLRSPFYNHYTETRLLLLLRLLGDYVPGVGLVARPLMDYLPVWQKIYFYNWG
What is the function of this protein?
Involved in peroxisome biogenesis.
What are the official names of this protein?
Peroxisomal membrane protein PEX16, Peroxin-16, Peroxisomal biogenesis factor 16.
What is the protein family that this protein belongs to?
Belongs to the peroxin-16 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.
Protein: NST1_YEAST
Sequence: MPPNSKSKRRKNKSKQHNKKNGNSDPEQSINPTQLVPRMEPELYHTESDYPTSRVIKRAPNGDVIVEPINTDDDKKERTANLTHNKDSMDSASSLAFTLDSHWESLSPEEKKTILRIEKEEVFNVIRNYQDDHSCSCSVCGRRHLAMDQEMERIYNTLYAMDKDKDPETNPIKFHLGIIKELQISKNQQQNDLSSTKGEVVKNFLSSSTVGSLKEEVLHFKQKQLSKQEQAHNETADNTSLLEENLNNIHINKTSSEISANFNSVSDEELQQKYSNFTKTFISSHPKIAEEYVQKMMMYPNIRALTDDLMNSNGQGFLNAIEDFVRDGQIQASKKDDSITEDEASSTDLTDPKEFTTMLHSGKPLTEDEYADLQRNIAERMTNAYDTASKKFKDVSQLEKELFTRFMSGRDKKSFRELIIQSFKNKFDGELGPSVLAATLSSCFSSQSKDTSLDTDSIYEDEDEEDYDDYSEYAEDSEEVSEYEGIEAVEKPEHDEKSNGIRETLHLSYDHDHKRQNHPHHHYHSTSTHSEDELSEEEYISDIELPHDPHKHFHRDDDILDGDEDEPEEEDENEGDDEEDTYDSGLDETDRLEEGRKLIQIAITKLLQSRIMASYHEKQADNNRLKLLQELEEEKRKKREKEEKKQKKREKEKEKKRLQQLAKEEEKRKREEEKERLKKELEEREMRRREAQRKKVEEAKRKKDEERKRRLEEQQRREEMQEKQRKQKEELKRKREEEKKRIREQKRLEQEKLQKEKEEEERQRLIAEDALRKQKLNEEQTSANILSAKPFTENGVGNPVSSQSHPNMTNYQEDNSCSINDEILKMVNSVAASKPVSPTGFNVHDLLLPSTNNQMPAMEQSHLPQPGNQNNHFGTTTIPNALDLATKSSLQTENNYLMNSQTLENTSLLMHNNSSPTKLLPNDFGLSSWGGLTNTMSINPTCKPPVIQTSEMESQAHKSSPQATMPSFGLPNGGTHRKSFTDELNTLTSMLSSSGFADTSLSSSGFPPSQRSVWNDQKSSFSGPSTAGNFNNSSIQSGMLLAPTLGSVESFPNRTSIWDSSTTPMMNKSELSGRNITSTAQDSPAFMASNIWSSNSQYNSPYLTSNVLQSPQISSGVDESHILDSIYNTYLAISPQDSLNPYIAIGTLFQNLVGLNLDYSTFINKLISMQGAYNCEFFTDNNGSITHVRFARQTPAGHSKGLLNQLFSGLNDPTATPFTSRPHTSTRASFPIASSTTQTS
What is the function of this protein?
With MSL1, acts as a negative regulator of salt tolerance.
What are the official names of this protein?
Stress response protein NST1, Negatively-affecting salt tolerance protein 1.
What is the protein family that this protein belongs to?
Belongs to the NST1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_SALTY
Sequence: MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSIRPLLTSAGINAGQLRTAIDQALSRLPQVEGTGGDVQPSSELVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLTDLLKSAGATTANITQAIEQMRGGESVNDQGAEDQRQALKKYTVDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELDDKERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQSEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMLEGEREKLLRMEQELHSRVIGQNEAVEAVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDDAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYGRMKEMVLGVVSQNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLQRLYKRLEERGYEIHISDEALKLLSANGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEANDDRIVAVQ
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).  Required for colonization of the gastrointestinal tract, probably due to protection from a combination of stress factors.
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAA_PINTH
Sequence: MTIRSPEPEVKKVKVVVDRDTVKTSFEKWAKPGHFSRTLAKGPDTTTWIWNLHADAHDFDSHTNNLEDISRKIFSAHFGQLAIIFIWLSGMYYHGARFSNYEAWLADPTHIKPSAQIVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALIFAALMLFAGWFHYHKAAPKLAWFQEVESMLNHHLAGLLGLGSLSWAGHQIHVSLPINQLLDAGVDPKEIPLPHEFIFNRDLLAQLYPSFAKGVTPFLTLNWSEYSDFLTFRGGLNPVTGGLWLTDTAHHHLAIAVLFLIAGHMYKTNWRIGHNLKDLLEAHKGPFTGEGHKGLYEILTTSWHAQLAVNLAMLGSLTIVVAHHMYSMPPYPYLATDYGTQLSLFTHHMWIGGFIIVGAAAHAAIFMVRDYDPTTQYNNLLDRVLRHRDAIVSHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPIFAQWIQNTHASAPGSTAPGATASTSLTWGGGDLVTVGSKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGNISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLLFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPAIQPRALSIVQGRAVGVAHYLLGGIVTTWAFFLARIIAIG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL3_CROS5
Sequence: MAVGLLGTKLGMTQIFEEESGLAIPVTVVQAGPCTITQIKTAETDGYSAIQIGYLEVKEKALTKPELGHLKKVEASPLRHLKEYRVDDTATYTLGEAVKADIFNAGDLVDIAGTSMGRGFAGYQKRHNFKRGSMTHGSKNHRLPGSTGAGTTPGRVYPGKKMAGQYGAVKTTTRHLQVVRVDAERNLLLIKGAVPGKPGGLLNITPAKIVGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: LEUO_SALTY
Sequence: MPEVKTEKPHLLDMGKPQLRMVDLNLLTVFDAVMQEQNITRAAHTLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPGSGFEPTSSERVFNLCVCSPLDNILTSQIYNRVEKIAPNIHVVFKASLNQNTEHQLRYQETEFVISYEEFRRPEFTSVPLFKDEMVLVASRKHPRISGPLLEGDVYNEQHAVVSLDRYASFSQPWYDTPDKQSSVAYQGMALISVLNVVSQTHLVAIAPRWLAEEFAESLDLQILPLPLKLNSRTCYLSWHEAAGRDKGHQWMEDLLVSVCKR
What are the official names of this protein?
Probable HTH-type transcriptional regulator LeuO.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RS15_GEOSM
Sequence: MLVTEKKQEIVNAHKLHDSDTGSPEVQIALLSERITYLTEHFKTHKKDHHSRRGLLKIVGQRRGLLDYLKKKDVERYKSIIAKLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.