PharMolix/UniProtQA huggingface dataset:
Protein: MKAR_ASPFC
Sequence: MEFLSKYTACLSNWGLNLEPGLQTVGAAVLLTTGTLFIASRVLTFVRVLLSLFVLPGKPLRSFGPKGSWAVVTGASDGLGKEFSLQLARAGFNIVLVSRTASKLTTLAEEITTKHSVQTKTLAMDYAANNDADYEELKAIVDGLDVAVLINNVGKSHDIPTPFALTPEDEMTDIVTINCLGTLRTTQLIIPGMMQRKRGLVLTMGSFGGLLPTPLLATYSGSKAFLQQWSTSLGSELEPYGITVELVQAYLITSAMSKVRRTSATIPDPRAFVKAVLSKIGRNGGSPGYAYSSSPYWSHGLMAWFLTCVMQPMGKLVVGQNKSMHEAIRKRALRKAEREKGKKST
What is the function of this protein?
Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate.  Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation.  VLCFAs serve as precursors for ceramide and sphingolipids.
What are the official names of this protein?
Very-long-chain 3-oxoacyl-CoA reductase, 3-ketoacyl-CoA reductase, 3-ketoreductase, KAR, Microsomal beta-keto-reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MTBP_XENLA
Sequence: MERFVLCIHWERRAEQQQPVPQGLVYAQDIYTQLKEYSTNCTSTFPACSLTGNPGIRKWFFALQSLYGFSQFCSSDWEDLCPAVTTDDSEEPVQTALDECLDALQFPDGEDDNSRDSISQTNLFEEAAELLHQLSDKLPAPGRALVDVLLFPSEAPKLKDCLSAIGAIKHLKEWHTAKITIVSKDCKGWQKIGKFLSANVVVSDCPRQLIDPQELWRGTIEIKERKFTSEVEFPEFCLRSVSDDKVPYFENNGDDKNKTVLSEVFHYYGASLEYVQMVALSEIPSYFVSDSVFELSITRNGLQGKSKLMLDQLCSLTEKVGAIFMLPCNVCSLPNPPALQRSSKKWREYMSRKPKDIKVPGVELKGEYCSYYFLIQGKGSGLCKATLLHSASQISGAASLLLLHQRLNNNHPVNMAESTSDILDSLPHFNGEQIALREQILARAQVLAVKEYLKRQEAQPHASVSQSNNLGRLLALTREHVIGDCESRLDSVSYKNMQNITVSTPAFPESEAMISNPADWPERNVLQNLENFEKIKQRLRASILSGSAEQLLGRKDGLKEGMTLLDAKELLKYFTPQGLAVGELQPLQVQRGDNAFLVTPKLTPRKLKGLPFEKAAECHYHGLEYCLDNRKALDRDVAFSELQSRLIRYETQTTCTRECCPIPFALSPIPSPAVLSEPGSVPDGESIQTELRGDPLRLKRRSKDIEGLYPSKRLAKSGSSDSLVSLASEGSGHQQPTRLRTERTASSVSGAQPSSTRVRTAPSVPAQSKPSSHLELEQKESRSQKHNRMLKEVVSKTLQKHSIGVEHPCYAACNQRLFEISKFFLKDLKTSRGLLDEMKKAASNNAKQVIQWELDKLKKN
What is the function of this protein?
May play a role in mdm2-dependent p53/TP53 homeostasis in unstressed cells.  Inhibits autoubiquitination of mdm2, thereby enhancing mdm2 stability.  This promotes mdm2-mediated ubiquitination of p53/TP53 and its subsequent degradation (By similarity).
What are the official names of this protein?
Mdm2-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MTBP family.
Protein: ILVC_SULDN
Sequence: MTVYYDKDCNINLIKSKKVAMIGFGSQGHAHAENLRDSGVEVVVGLRKDGSSWAKAEAKGFKVMTVGDASAYADLIMILLPDENQAEIYKDEIEPNLKNGATIAFGHGFNIHYGRIHPRADINVTMIAPKAPGHTVRSEFVRGGGIPDLIAVGQNPSGNTRELALSYASAIGGGRTAIIETTFKDETETDLFGEQAVLCGGAVSLVQAGFETLTEAGYAPELAYFECLHELKLIVDLMFQGGIADMRYSISNTAEYGDYVSGKRVINAESKAAMREILKEIQDGRFAKDFILEGQSGYPRMNAERANAKASLIEQTGVKLRTMMPWIAANKIVDTSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MIAA_RHIEC
Sequence: MENLLSVENAILITGPTASGKSALAVELAKRHNGAVVNADSMQVYDTLRVLTARPSEEEMQGVPHHLYGHVPAWAGYSTGAWLRDVSALLPALRAAGQLPVFVGGTGLYFKALTGGLSDMPDIPEALREELRRRLVEEGTDALYAELSDVDPAMAAGLNRQDGQRIVRALEVTKATGRSIADFQGRSGPVVIDADEARKIVVLPDRAVLHARINGRFEKMLQQGAEDEVKALLALGLPAEAPVMKAIGVSQIAAMLKGEMTRDEVLEKGAAATRQYAKRQMTWFRNQMDDSWQRLTH
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: KDSB_FRATO
Sequence: MANIHIVIPARLKSTRLPNKMLADIAGKPMIQRVYEQVTKSKFDSIIIATDSQKIKDIAESFGAKVVLTRDDHQSGTDRIAEAVTKLGFADEDIVVNVQGDEPLIPIENIEQAAQLLIDKSEAVVSTLCEKITDVEDIYNPNNVKVVFDKNNYALYFSRASIPFERGFSEKEQINISEFFRHIGIYAYRVAFLKHYAELTVSPIEKYEALEQLRVLYNGYKIAIEQSAKSTPAGVDTLQDLEKVRKLFNV
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_BACLD
Sequence: MSYLIKNGFMLDEKGEKVQRDIRVEGDAISEIGSLEAASGETVIDADGLFVSPGLVDLHVHFREPGGEKKETIETGAKAAARGGFTTVAAMPNTRPVPDTKEQMEWLVNRIDETASVRVLPYASITIRQTGREMTDFEGLKDAGAFAFTDDGVGVQTAGMMYEAMKKAASINKAIVAHCEDNSLIYGGSVHDGEFAKANGLNGIPSVCEAVHIARDVLLAEAAGCHYHVCHISTKESVRVVRDAKKAGIRVTAEVTPHHLLLSDSDIPGLDTNYKMNPPLRSPEDREALLEGLRDGTIDFIATDHAPHTEEEKQQTMSLAPFGIVGLETAFPLLYTHFVKTGKWTLKQLHDYMTVKPCEAFGLPYGKLEAGRSADITLIDLEREEKIDKSTFLSKGKNTPFDGISCFGWPAMTMAKGKLVYQEGRLVK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: ERPA_VESOH
Sequence: MEIKQISEKADIIFSDNAAKKVSTLIEEEQNNNLYLRVYITGGGCSGFSYGFTFDEKRKEGDSSVTNNGVQLVIDPMSYQYLIGATVDYLEDLQGARFIIHNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: SUGFT_MYCTO
Sequence: MTILILTDNVHAHALAVDLQARHGDMDVYQSPIGQLPGVPRCDVAERVAEIVERYDLVLSFHCKQRFPAALIDGVRCVNVHPGFNPYNRGWFPQVFSIIDGQKVGVTIHEIDDQLDHGPIIAQRECAIESWDSSGSVYARLMDIERELVLEHFDAIRDGSYTAKSPATEGNLNLKKDFEQLRRLDLNERGTFGHFLNRLRALTHDDFRNAWFVDASGRKVFVRVVLEPEKPAEA
What is the function of this protein?
Sugar N-formyltransferase that catalyzes the conversion of dTDP-4-amino-4,6-dideoxyglucose into dTDP-4-formamido-4,6-dideoxyglucose using N(10)-formyltetrahydrofolate as the carbon source.  Plays a role in virulence.
What are the official names of this protein?
dTDP-4-amino-4,6-dideoxyglucose formyltransferase, dTDP-Qui4N formyltransferase, Sugar N-formyltransferase MT3512.
What is the protein family that this protein belongs to?
Belongs to the dTDP-Qui4N formyltransferase family.
Protein: PYRE_SHIB3
Sequence: MKPYQRQFIEFALGKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGLEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: Y693_VIBCH
Sequence: MLSALLIDDERFAREELAELLAESGQIEVIGQASNAIEGLKKINQLKPDVVFLDIQMPQISGIELLSMLDPETMPEVVFVTAYDQYALQAFEDNAFDYLLKPVDTERLAKTVQRLLRQHKKSDYSPLTQPSLDQIPCTGLNRIVLLPINEVEFAYSDISGVNVQTAQQKATSQLTLKVLEEKTALVRCHRQYLVNLKAIREIKLLENGLAEMITHAGHKVPVSRRYLKELKEMLGFY
What are the official names of this protein?
Uncharacterized response regulatory protein VC_0693.
Protein: BCP1_GIBZE
Sequence: MGKKRAREEVKDVPPTDVNMMDEDGSDDEDFDMVNVDFEWFNFDPEVDFHGTKTLLRQLFDVDANLFNMSALADLVLSQPTIGSTIKVDGKANDAYALLTVLNTAVHQDKEPMKDIIKYLVEKAQTNSSLAPIADVLSSGKHVGLVFSERLINMPSELAPPLYSMLVDEVEAAVEDKEPYNFSHYLILSKTYQELESKLDVENQKRKKAKEEAGMYYFHMEDEVLHKHAVAHGNFNYTKEDELAADSKRAFQEMGVKAHGHMILIEASKFPGAVKSVNEYLSAAQ
What is the function of this protein?
Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
What are the official names of this protein?
Protein BCP1.
What is the protein family that this protein belongs to?
Belongs to the BCP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GDPD1_HUMAN
Sequence: MSSTAAFYLLSTLGGYLVTSFLLLKYPTLLHQRKKQRFLSKHISHRGGAGENLENTMAAFQHAVKIGTDMLELDCHITKDEQVVVSHDENLKRATGVNVNISDLKYCELPPYLGKLDVSFQRACQCEGKDNRIPLLKEVFEAFPNTPINIDIKVNNNVLIKKVSELVKRYNREHLTVWGNANYEIVEKCYKENSDIPILFSLQRVLLILGLFFTGLLPFVPIREQFFEIPMPSIILKLKEPHTMSRSQKFLIWLSDLLLMRKALFDHLTARGIQVYIWVLNEEQEYKRAFDLGATGVMTDYPTKLRDFLHNFSA
What is the function of this protein?
Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (PubMed:27637550, PubMed:25596343).  Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC) (PubMed:27637550, PubMed:25596343).  May be involved in bioactive N-acylethanolamine biosynthesis from both N-acyl-lysoplasmenylethanolamin (N-acyl-lysoPlsEt) and N-acyl-lysophosphatidylethanolamin (N-acyl-lysoPE) (PubMed:27637550, PubMed:25596343).  In addition, hydrolyzes glycerophospho-N-acylethanolamine to N-acylethanolamine (PubMed:27637550).  Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine (By similarity).
What are the official names of this protein?
Lysophospholipase D GDPD1, Glycerophosphodiester phosphodiesterase 4, Glycerophosphodiester phosphodiesterase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Endoplasmic reticulum. Note=Concentrated at the perinuclear region and the cell periphery (PubMed:18991142).
Protein: KCY_BRUME
Sequence: MKSFVVAPFIVVIDGPAASGKGTLARRIATHYGMPHLDTGLTYRAVAKALLDKGLPLDDEALATDAALSLDLLAMDKAVLSAHAIGEAASKVAVMPAVRRALVEAQRHFANALPSSVLDGRDIGTVVCPDAAIKLFVTASPEVRARRRFDEVLARGDTADFAEILADLKKRDERDMNRTDSPLRPAEDAHLLDTSEMSIEAAFLAAKKLIDHALAQHRG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_STRS7
Sequence: MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTEMGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLEALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDDKPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_XANCB
Sequence: MSDNNEKQTLRTVEGRVVSNKMDKTVTVLVERQVKHPLYGKYIKRSSKLHAHDADNACNEGDVVRVTEIAPMSKTKNWRVVEIVSRAAV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PERL_MOUSE
Sequence: MKVLLHLPALLASLTLLQTAASASDDPTAETDIIHDTVEEVKVWVNKAFLDSRDRLKMAMTTKIHSTRHLSDYLKHAKGRTRTAIRSGQVWEESLKKLSQFLTNVTGQGLDLTLLSWEAGCDPPAPTMTCNISSPYRTITGYCNNRKNPALGSANRALARWLPAEYEDGLSLPYGWTPGKMRNGFPLPQPREVSNQIAAYLNEEDVLDQKRSMLFMQWGQIVDHDMDFAPETEMGSDTYTKAQCDEHCIQGDNCFPIMFPPGDPKLKTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASLVYSPEPSLANRLRNLSSPLGLMAVNEEVSDNGRPFPPFVKMKPSPCEVINATAGVPCFLAGDSRASEQILLATSHTLFIREHNRLATELSRLNPHWDRETLYQEARKIMGAFIQITTFRDYLPILLGDEMQKWIPPYQGYNESVDPRISNVFTFALRFGHLEIPSTVYRLDENYQPWGSESELPLHTVFFNTWRLVKDGGIDPLVRGLLAKNAKLMHQNKMMTGELRNKLFQPNHTIHGFDLASINIQRSRDHGQPGYNSWRAFCGLSQPKTLEELSAVMKNEVLAKKLMDLYGTPSNIDIWLGAVAEPLVHRGRVGPLLTCLLGQQFQRIRDGDRFWWENPGVFTEKQRESLQKMSFSRLVCDNTGIDKVPLNPFQANAYPHGFVDCSSIDKLDLSPWASVKE
What is the function of this protein?
Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2) (By similarity).  Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2 (By similarity).  Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism (By similarity).  May be implicated in airway host defense against infection (By similarity).  May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation (PubMed:34127712).
What are the official names of this protein?
Lactoperoxidase, LPO.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Expressed in the cytoplasm in intestinal epithelial cells.
Protein: DAPB_BURMA
Sequence: MSSMKIAIAGASGRMGRMLIEAVLAAPDATLAGALDRTGSSQLGQDAGAFLGKQTGVALTDDIERVCAEADYLIDFTRPEGTLAHLDAALRHDVKLVIGTTGFSEPQKAQLRAAGGKIALVFSANMSVGVNVTMKLLEFAAKQFAQGYDIEIIEAHHRHKVDAPSGTALMMGETIAAATGRTLDDCAVYGRHGVTGERDPSTIGFSAIRGGDIVGDHTVLFAGIGERIEITHKSASRVSYAQGALRAARFLAGHQAGFFDMQDVLGLR
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_FUSNN
Sequence: MKIALDAMSGDFAPISTVKGAIEALEEIEGLQVILVGKEGIIKEELKKYKYDTNRIEIKNADEVIVMTDDPVKAVREKKDSSMNVCIDLVKEKLAQASVSCGNTGALLASSQLKLKRIKGVLRPAIAVLFPNKKDSGTLFLDLGANSDSKPEFLNQFATMGSKYMEIFSGKKNPKVALLNIGEEETKGNELTRETYALLKENKDIDFYGNIESTKIMEGDVDVVVTDGYTGNILLKTSEGIGKFIFHIVKESIMESWISKLGALLVKGAMKKVKKKTEASEYGGAIFLGLSELSLKAHGNSDSRAIKNALKVASKFIELNFIEELRKTMEVE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: SSRP_CHRVO
Sequence: MSIIQNRKAFHDYFIEEKLEAGLVLEGWEVKAIRAGRVQLKESYVDWKNGAFWLIGCHITPLQSASTHVKPDPVRPRKLLMSQAEINRFIGKVERAGYTMMALDLHYTKGNVKAEVGLAKGKKLHDKRDTEKDREWQREKQRVMKNQRGAA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SIX3G_LEIHE
Sequence: MKLLLLLTISASMLIEGLVNADGYIRGGDGCKVSCVINHVFCDNECKAAGGSYGYCWGWGLACWCEGLPAEREWDYETDTCGGKK
What is the function of this protein?
Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently at site-4 of sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current.  This depressant toxin is active only on insects.  It is found in a relatively small amount in the venom.
What are the official names of this protein?
Beta-insect depressant toxin Lqh-dprIT3g.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRC_STRP1
Sequence: MNELIKHKLELLPDSPGCYLHKDKEGTIIYVGKAKNLKKRVRSYFRGSHDTKTELLVSEIVDFEYIVTESDTEALLLEINLIQKNMPKYNIKLKDDKSYPFLKITNESFPRLVITRYIKKNDGLYFGPYPDSYTANEVKKLLDRIFPFKKCKNPINKVCFYYHLGQCCAHTICHTDKAYWDRLIDDVKHFLNGKDDKIIEDLRSKMLAASKEMAFERAAEYRDLISGIATMRTKQRVMSKDLQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNLFPYYTDAEEDFLTYMGQFYQDKQHFIPKEVFIPEAIDEELVAAIVPTKIIKPKRGEKKQLVALATKNARVSLQQKFDLLEKDIKKTSGAIENLGQLLRIDKPVRIEAFDNSNIQGTSPVAAMVVFVDGKPSKKDYRKFKIKTVVGPDDYASMREVLFRRYSRVKKEGLQAPNLIIVDGGVGQVNVAKDVIEKQLGLTIPVAGLQKNDKHQTHDLLFGNPLEVVPLPRRSEEFFLLHRIQDEVHRFAVTFHRQVRRKNSFSSTLDHISGLGPKRKQLLLRHFKTITAIASATSEEIQALGIPKTVVEAIQQQITDNKNDRSSP
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTIB_BACSU
Sequence: MSLLNDILEFNKTFTEQREYEKYQTSKFPDKKMAILSCMDTRLVELLPHAMNLRNGDVKIIKSAGALVTHPFGSIMRSILVAVYELNADEVCVIGHHDCGMSKISSKSMLEKIKARGIPEERIETIKYSGVDFDQWFKSFDSVEASVKDSVDVIKHHPLFPENVPVHGLVIDPKTGKLDLIVNGYNN
What is the function of this protein?
Reversible hydration of carbon dioxide.
What are the official names of this protein?
Putative carbonic anhydrase YtiB, Carbonate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the beta-class carbonic anhydrase family.
Protein: DBP7_SCHPO
Sequence: MADEPLLLNFVVDNAQSRKPEALKSSRRWTDRARDRKRQKRNSNESSKSTVKRNSGTNGASTDYKNSQKEKVINPVFDPRKPAHELKGNKRDNTFVTSLFTGDDSEHFSQDVGQNLEDNQISNIGTTKEASNAPIKTTNFAGVQLDTQLADHLNNKMNISAPTAIQSCCLPALLNTDDKDAFIEAQTGSGKTLAYLLPIVQRLIRLPKNLHTRTSGIYAVIMAPTRELCQQIYNVANKLNNNPLSHWIVSCNVIGGEKKKSEKARIRKGVNILIGTPGRLADHLENTEALDVSQVRWVVLDEGDRLMDMGFEETLTKILSYLESQSSIIKKDLSIPSRKVTMLCSATMKDTVKRLSDSALKDALYLKSSIVEETNDGYSQAPEQLLQRYVVVPPKLRLVSLVALLRSHVRSYKKIIIFLSCSDSVDFHFEAFRCAINADEMEEAVKEKPDSEGDIISNAPALRIDGKSNVYRLHGSLSQQIRTSTLNLFSSSEDSGSHILLCTDVAARGLDLPNVDLVVQYDAPFSTDDYLHRIGRTARAGHNGAAIMFLLPKESEYINLLKSSVSANILEQPNGPSGLLSAGFSQGKTNTNDWQDRATEWQLELERFILENEPMRNIAKRAFTSYVRAYATHLSSERSIFNMRDLHLGHIAKSFALREAPGKISGANSSKPRKQGGSVDKGKSKSSKDIAALMHRKAMEHYSTEHNIG
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp7.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DTDA_SACS2
Sequence: MDIKLVYSTLDPVGVTIKKLGYRFEEINEDVTDFHYENGEAIVIFSRHESKAGIPSLTVHYPGNPSEEIMGGEPKKLGIAYPRLLTSILREIKKIDLNIEKTMEATHHGPTYQNVPVIFVEVGSNETYWTNDTIVKALVDSTIRSIDKVDEIDCEYYISGFGGPHYSRLFTKLADESCIGHVISKHYIDKLDDKVIIQTITNSVNTINKVVIDSLNSKQKERIIASLKKLNNINIEFR
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.  Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr).
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: RL4_BRADU
Sequence: MELKVTTLEGKEAGSVQLSDAIFGLEPRQDIIARCVQWQLNKRQAGTHKAKGRAEIWRTGKKMYKQKGTGGARHGSARVPQFRGGGRAFGPVVRSHATDLPKKVRALALKHALSAKAKDGDLLVIDKAALEAAKTKALLGHFSGLGLTNALIIDGAELNNGFAAAARNIPNMDVLPIQGINVYDILRRQKLVLTKAAIDALEARFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: AADK_CAMJU
Sequence: MRSEKEVYDIVLNFAKTDKRIRMVTLEGSRTNTNIPPDDFQDFDITFFVTDMDSFTSDDKWLDIFGERLILQKPEDMELFPAVEKGFSYLMLFTDDVKIDLTLLPLELIDEYFTWDKLVKLLLDKDNRIVKPPIPTDIDYHLQKPTQRMFDDCCNEFWNTTTYVVKGLCRKEILFAIDHMNDIVRKELLRMISWLIGIKQGFHFSLGKNYKFMKQYVPEELWERLMSTYNMDSYPHMWESFEQCMALFREVSSEVACQLDYQYPLYDEKISNYVIRQKKKYGIEDDNK
What is the function of this protein?
Mediates bacterial resistance to streptomycin, is probably a streptomycin 6-adenylyltransferase.
What are the official names of this protein?
Aminoglycoside 6-adenylyltransferase, ORF2, Streptomycin 6-adenylyltransferase.
Protein: PHAT_AMAPH
Sequence: PAWLVDCPCVGDDINRLLTRGEK
What is the function of this protein?
Major toxin that belongs to the bicyclic heptapeptides called phallotoxins (PubMed:24613547).  Although structurally related to amatoxins, phallotoxins have a different mode of action, which is the stabilization of F-actin (PubMed:24613547).  Phallotoxins are poisonous when administered parenterally, but not orally because of poor absorption (PubMed:24613547).
What are the official names of this protein?
Phallacidin proprotein 1.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.