PharMolix/UniProtQA huggingface dataset:
Protein: OTCC_BACCR
Sequence: MLMTRPNLKGRSFLAEKDFTQEELLYFLDLAAELKEKKKNGIPHHYLEGKNVALLFEKTSTRTRCAFTVACTDLGANPEYLGKGDIQLGKKESVEDTAKVLGRMFDGIEFRGFNHETVESLAQNSGVPVWNGLTDMWHPTQTLADLLTIREHIGKLKNVKLVYVGDGRNNVANSLLVGGAIVGMDVRICTPESLWPAQEVIDLAKKYNEQVMITSNVEEAVANADVIYTDVWVSMGEEEKFAERVELLKPYQVNMKMIKATGNENVIFLHCLPAFHDVETMYGEEVYEKYGLKEMEVTDEVFRSKHSKVFDQAENRMHTIKAVMAATLGNME
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSR2A_XENLA
Sequence: MGSKALPAPVPLHPSLQLTNYSFLQAVNTFPAAVDHLQGLYGLSAVQTMHMNHWTLGYPNLHGLTRSTITEMAAAQGLMDARFSFPALPFATHLFHPKQGTIAHVIPALHKDRPRFDFANLAIAATQEDPPKIGDLSKLSPGLGSPISEISKLSPDRKPSRGRLPSKTKKEFICKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQDHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHMQTSSPTVVSSAEKFSGEIAI
What is the function of this protein?
Transcriptional repressor.  Required for pronephric kidney development.
What are the official names of this protein?
Protein odd-skipped-related 2-A, XOsr2.
What is the protein family that this protein belongs to?
Belongs to the Odd C2H2-type zinc-finger protein family.
Protein: SYDND_METNO
Sequence: MHRYRSHTCGALRPSDVGSTVRLSGWCHRVRDHGGVLFIDLRDHYGLTQCVVDADSPAFRAAEAVRSEWVIRIDGRVRQRPAGTENPDLPTGAVEVYIADLEVLGHAVELPMPVFGDLDYPEETRLRYRFLDLRREKLHANIMKRGAIIDSLRRRMREGGFFEFQTPILTASSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLTMIAGFDRYFQIAPCFRDEDARADRSPGEFYQLDIEMSFVTQEDVFQAVEPVLRGVFEEFADGWRVTQSFPRIPYAEAMLKYGVDKPDLRNPLLIVDVTEEFSAEAVTFNAFKNLIRAGGVVRAIPAPGAASQPRSFFDKLNDWARSEGAPGLGYIVFEEEGGQLIGRGPIAKFVPAEVQAAIAGKAGLKAGDAVFFSAGTEAKAAGLAGKARIRIGDDLGLSDKDQFAFCWITDFPMYEWNEDEKRIDFSHNPFSMPNYDHKAFLALDPADADTILGIKAFQYDIVCNGIELSSGAIRNHRPDVMEKAFAIAGYGRDVLEQKFGGMLNALRMGAPPHGGIAPGVDRIVMLLCHEPNIREVVLFPMNQRAEDLMMGAPSEVTAKQLRELHIRLNLPEKSA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANO3_MOUSE
Sequence: MVHHSGSIQSFKQQKGMNISKSEITTEASLKPSRRSLPCLAQSYAHSKSLSQSASLFQSTESESQAPTSVTFLSADKPEHVTSEESRKDSTLKCSFADLSDFCLALGKDKDYLDESEHANYDRSRLLNDFVTKDKPASKTKLSKNDMSYIASSGLLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIANPDIMFIKIHIPWDTLCKYAERLNIRVPFRKKCYYTDQKNKSKSRVQNYFKRIKKWMSQNPMVLDKSAFPELEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVGIRKLITNGSYIAAFPPHEGAYKSSLPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRMYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNESQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEEETLRPQFEAKYYRMEVINPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFVKQHWQFATSGAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFERWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDASIPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGMGKSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEMMYEAELEHLQQQRRKSGQPIHHEWP
What is the function of this protein?
Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylcholine and galactosylceramide (PubMed:23532839).  Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:23532839).  Seems to act as potassium channel regulator and may inhibit pain signaling; can facilitate KCNT1/Slack channel activity by promoting its full single-channel conductance at very low sodium concentrations and by increasing its sodium sensitivity (PubMed:23872594).
What are the official names of this protein?
Anoctamin-3, Transmembrane protein 16C.
What is the protein family that this protein belongs to?
Belongs to the anoctamin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Shows an intracellular localization.
Protein: HISZ_STAAC
Sequence: MNNSEQLIALKESETAFLKYFNKADYELVDFSVVEKLDWKQLNHEDLQQMGERNFWQHEHQIYALRNDFTDQLLRYYSMYPTAATKVAYTGLIIRNNEAAVQVGLENYAPSLANVQQSLKLFIQFIQQQLRDNVHFVVLGHYQLLDALLDKSLQTPDILSMIEERNLSGLVTYLSTEHPIVQILKENTQQQLNVLEHYIPNDHPALVELKIWERWLHKQGYKDIHLDITAQPPRSYYTGLFIQCHFAENESRVLTGGYYKGSIEGFGLGLTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB2_AMBCR
Sequence: VHWTAEEKQLITCLWGKVDVATIGGESLAGMFVMYPWTQRLFSEFGNLSSPTAICGNPKVKAHGKKVLTAFGDAIRNLDNIKDTFAKLSELHCDKLHVDPENFKLLGKVLLIVLAGHYGKDFTPACHAAYQKLVNVVAHALARRYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, Hemoglobin beta-2 chain, Hemoglobin beta-II chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: UGPB_ECOL5
Sequence: MKPLRYTASALALGLALMANAQAVTTIPFWHSMEGELGKEVDSLAQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIKPVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDGTDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKPENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADIATRQMLNKPPLPFTKGLRLGNMPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Binds G3P.
What are the official names of this protein?
sn-glycerol-3-phosphate-binding periplasmic protein UgpB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GHRB_ECOLU
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTIEQNAAIFAEAEGLLGSNENVDAALLGKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDSLLQESDFVCLILPLTDETYHLFGAEQFGKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UDP_KLEPN
Sequence: MSKSDVFHLGLTKNDLQGATLAIVPGDPERVEKIAALMDKPVKLASHREFTSWRAELDGKSLIVCSTGIGGPSTSIRVEELASTLGVDSRTLTPRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPMEFPAVETSTATRAGEARKSIGATTIGVTASDTFYPGQERYDTSGRERNSRSHIVRTLSILYQQQTYDTYSRVERFKGSMEEWQAMGVMNYEMESATVLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKSTESQFAVKIVVEAARRLL
What is the function of this protein?
Catalyzes the reversible phosphorylytic cleavage of uridine to uracil and ribose-1-phosphate.
What are the official names of this protein?
Uridine phosphorylase, UPase, UrdPase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_SALTI
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKGLWVVTAVVTVVILYVALFW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_NITEC
Sequence: MRKAQVTRNTQETQITVAINLDGQGKAELDSGVPFLDHMLDQIARHGMIDLNVAAKGDLHIDAHHTVEDIGIALGQALNRAIGDKKGIFRYGHAYVPLDETLSRVVIDLSGRPGLQFNTTFTRAVIGSFDVDLIQEFFQGFVNHAMMTLHIDNLAGKNAHHQAESIFKAFGRALRMAVTIDPRCDDLIPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_BACCN
Sequence: MNYLFKNGRYLNEEGTIVATDLLVQDGKIAKIAKNISAENAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDSKEHMEDLQKRIQEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSVDPNFKMNPPLRGREDQEALIEGLLDGTIDIIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLETGRLKEGRAADITILDLEQEEKIDPTTFLSKGKNTPFAGWKCQGWPVMTLVGGKIVWQKESALV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: HOT_XENLA
Sequence: MAAGRDGVIHLLRQLQRASCRCPAHSHTYSQAPATARTTDYAFEMAVSSIRYGENVTQEIGMDLQNWGTRNVCVMTDRNLSELSPVKAVLNSLVKNGINFKLYDSVRVEPTDKSFMDAIEFAKKGQFDAFVAVGGGSVIDTCKAANLYSSSPDSDFLDYVNPPIGKGKAVTVPLKPLIAVPTTSGTGSETTGIAIFDYEELKAKTGIASRAIKPTLGLIDPAHTLSMPERVVANSGFDVLCHSLESYTALPYNMRSPCPTNPINRPAYQGSNPISDVWAKHALRIVAKFLKRAVRNPDDREARFAMHLASSFAGVGFGNAGVHLCHGMSYPIAGHVKTYRAKDYKVDHPLVPHGLSVVLTSPAVFSFTGLMCPERHLEAAEILGADLRTAKIKDAGLILADTLRKFLYDLNVDDGLAAVGYTAEDIPALVKGTLPQERVTKLSPRAHSEEELAALFEASMKLY
What is the function of this protein?
Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG).  L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity).
What are the official names of this protein?
Hydroxyacid-oxoacid transhydrogenase, mitochondrial, HOT, Alcohol dehydrogenase iron-containing protein 1, ADHFe1.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MTNC_KLEAE
Sequence: MIXAIVTDIEGTTSDTXFVXNVLFPY
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: NUOK_DEIGD
Sequence: MAPTAYYVALSGLLFAIGMIGVLTRRTAIMIFLSVELMLNAANLALVAFARAWGDLTAQTAVFIVMTLAAAEVAIGLAIIVAIFRKRETTNVDDLATLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LGUL_VIBCH
Sequence: MSNHRILHTMLRVGDLDKSIEFYTQVMGMSLLRKNENTEYKYTLAFLGYGDESQGAVIELTYNWGVADYEKGNAYGHIAIGVDDIYATCDTIKAAGGIVTREPGPVKGGTTHIAFVKDPDGYMIELIQNKQAHAGLEG
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
What are the official names of this protein?
Probable lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: RL13_HALH5
Sequence: MRTTYMAKPNEVERKWYVVDAEGQTLGRLASEVASILRGKHKPTYTPHVDTGDHVIIINAEKIHLTGNKLQDKIYYRHSGHPGGLKETRAADMRANKPEKMLELAIKGMLPKNTLGRKQGMKLHVYAGSEHKHQAQKPEVYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MIC60_ASHGO
Sequence: MLSSRAAAFTGRRLASTLPPVPRKKSHGVRRLLAKAVVATSLFYAGGLTLSAYNDKANELFVEHVPFGEELVERWEDWTSLRRPGRRMIDARRVDEISRDFRAAATPEATPVVVRPLVQLQLPELQMQGSSPVLEALVNNVNDVVVALNARALELPEDTASALSSVYGEIVHSIQALNASLDQEFATEVESRTGKAISSVQEQLEVEYKQRELALAEQYIQNFEVFKSQLQKATAEQLETELKAHEQALLARHRNEVAQLSIRQVEEFNKIIEKKLDQERNGRLAKLSELNSAVESLAPVLDRLELRAVKNECVTQLSTLISDIQGKLSRGGDEPLDLSSDLQRLTLLADILPRPKRCCSEGPALLDVAMAELQAKAQAPVASNEQLYNRWQLLQPELKTTSLLPPNAGFLGHLTAKLFSMLLFTKEGFSTTQDMDAVTARIAENLRLNKLDCALEEAVNMKGWSRKSADAWVDLARRRLEVLTLLDVIEAEVKTL
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.  Plays a role in keeping cristae membranes connected to the inner boundary membrane.  Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
What are the official names of this protein?
MICOS complex subunit MIC60, Mitofilin.
What is the protein family that this protein belongs to?
Belongs to the MICOS complex subunit Mic60 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: HVCS_HETFR
Sequence: ATPSPPTLYGLCSCEQPNTDGSLAYGCLAMDYIPQITSVSWKKDNEPITTGLKTYPSVLNKKGTYTQSSQLTITESEVGSSKIYCEVRRGESVWIKEIPDCKGDKVHPTVILTQSSSEEITSRRFATVLCSIIDFHPESITVSWLKDGQHMESGFVTSPTCGVNGTFSATSRLTVPAREWFTNKVYTCQVSHQGVTQSRNITGSQVPCSCNDPVIKLLPPSIEQVLLEATVTLTCVVSNAPYGVNVSWTQEQKSLKSEIAVQPGEDADSVISTVNISTQAWLSGAEFYCVVNHQDLPTPLRASIHKEEVKDLREPSVSILLSPAEDVSAQRFLSLTCLVRGFFPREIFVKWTVNDKSVNPGNYKNTEVMAENDNSSYFIYSLLSIAAEEWASGASYSCVVGHEAIPLKIINRTVNKSSGKPSFVNISLALLDTVNSCQ
What are the official names of this protein?
Ig heavy chain C region, secreted form, Clone 3050.
Protein: NUOD_HELHP
Sequence: MKQNYTKLKPNFENIFFEQENDKMILNFGPQHPSAHGQLRLILELENEKIIKATPDIGYLHRGIEKMAENMIYNEFMPTTDRLDYIAATSNNYAFALGVEKLIGVDIPLRAQVIRTMLLEINRIISHIFLLGVQGMDVGALSIFLYCFIEREYGLDLMEDYCGARLTHNAIRIGGVPLDLPHNFLESVEKFTHSVPKTLDLVRGLLDKNRIWRIRLENVGYISQDFAKQWSLSGIMARGSGIKWDIRKHNPYELYSELDFEVPIATEGDCYARYQLYIEEIYESLKIIKQLIAMYPSTPKEIMAKDARYISAPKEDIMTQNYSLMQHFVLVTQGMRPPVGEVYVPTESPKGELGFFINSQGAPSPHRLKIRTPSFYHIGVLQELLIGHYFADIPAILASTNVVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SSRP1_HUMAN
Sequence: MAETLEFNDVYQEVKGSMNDGRLRLSRQGIIFKNSKTGKVDNIQAGELTEGIWRRVALGHGLKLLTKNGHVYKYDGFRESEFEKLSDFFKTHYRLELMEKDLCVKGWNWGTVKFGGQLLSFDIGDQPVFEIPLSNVSQCTTGKNEVTLEFHQNDDAEVSLMEVRFYVPPTQEDGVDPVEAFAQNVLSKADVIQATGDAICIFRELQCLTPRGRYDIRIYPTFLHLHGKTFDYKIPYTTVLRLFLLPHKDQRQMFFVISLDPPIKQGQTRYHFLILLFSKDEDISLTLNMNEEEVEKRFEGRLTKNMSGSLYEMVSRVMKALVNRKITVPGNFQGHSGAQCITCSYKASSGLLYPLERGFIYVHKPPVHIRFDEISFVNFARGTTTTRSFDFEIETKQGTQYTFSSIEREEYGKLFDFVNAKKLNIKNRGLKEGMNPSYDEYADSDEDQHDAYLERMKEEGKIREENANDSSDDSGEETDESFNPGEEEEDVAEEFDSNASASSSSNEGDSDRDEKKRKQLKKAKMAKDRKSRKKPVEVKKGKDPNAPKRPMSAYMLWLNASREKIKSDHPGISITDLSKKAGEIWKGMSKEKKEEWDRKAEDARRDYEKAMKEYEGGRGESSKRDKSKKKKKVKVKMEKKSTPSRGSSSKSSSRQLSESFKSKEFVSSDESSSGENKSKKKRRRSEDSEEEELASTPPSSEDSASGSDE
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.  The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II).  Binds specifically to double-stranded DNA and at low levels to DNA modified by the antitumor agent cisplatin.  May potentiate cisplatin-induced cell death by blocking replication and repair of modified DNA.  Also acts as a transcriptional coactivator for p63/TP63.
What are the official names of this protein?
FACT complex subunit SSRP1, Chromatin-specific transcription elongation factor 80 kDa subunit, Facilitates chromatin transcription complex 80 kDa subunit, FACT 80 kDa subunit, FACTp80, Facilitates chromatin transcription complex subunit SSRP1, Recombination signal sequence recognition protein 1, Structure-specific recognition protein 1, hSSRP1, T160.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Chromosome. Note=Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Protein: NU2C1_ARATH
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDLTSDQKDIPWLYFISSTSFVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDLITIFVALECFSLCSYLLSGYTKKDIRSNEATMKYLLMGGASSSILVYGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSLAPFHQWTPDVYEGSPTPVVAFLSVTSKVAALALATRIFDIPFYFSSNEWHLLLEILAILSMIFGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYIAMNLGTFACIILFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVLSIYYYLKIIKLLMTGRNQEITPHMRNYRISPLRSNNSIELSMIVCVIASTILGISMNPIIAIAQDTLFSF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PROD_CAEEL
Sequence: MQAALIGLNFPLQRRFLSGVLTTTSSAKRCYSGDTGKPYDCTSAEHKKELEECYNRLDLSFENTKEAFKSKSNTELVRALVVLRLCGIQTLVNQNQIILNTMRRVLGKNLFKKTLKNTFFGHFVAGETEEEVRHVVEKLRNYGVKSILDYSVEADITSQEATDKTVKGTSVATVKPAAMTPVVDAKTLETTRERYTVHEEFGDRRQGVSSARTYFYEGEEQCDKNRDIFKDSINAVASATKNEGFVAVKITALGRPQLLLKLSEAIVQTQNFFKALTGGMSLQEGRLTSQEFYKRLGELGVKTDTESVKKFFDEVDFDSDGIVDLHGWNHILDDHVKLGQLFQVLNIKTGSLEPLIQNLSNEEEQEFRNMVRRTLDVAEYAIEKGVRIMVDAEQTYLQPAISKITIEMMKKYNKGRGNIFNTYQAYLKGTLQNMEADMQVARREGWHFGAKLVRGAYMEQERARAKAIGYEDPINDNFEATSKMYESCLTRIADEVHRRGKTNVSVMVASHNEDTVRFALNLMKEKCISPSERVMCMAQLYGMCDQVSFSLGQAGFSVYKYLPYGPVEEVLPYLSRRALENGSVLKKANKERDLLWKELKRRISSGEFKARSSSSS
What is the function of this protein?
Converts proline to delta-1-pyrroline-5-carboxylate (By similarity).  Through proline catabolism, promotes reactive oxygen species (ROS) production and the transcription of skn-1 target genes in response to bacterial infection by P. aeruginosa (PubMed:27974198).
What are the official names of this protein?
Proline dehydrogenase 1, mitochondrial, Proline oxidase.
What is the protein family that this protein belongs to?
Belongs to the proline oxidase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYH_LEPIN
Sequence: MENQKNFLTTAPYKGTRDFYPEDMRLRNWMFSVMRETVLSFGYEEYDGPILESFDLYKAKSGEEIVERQLYDFIDKGERRVAIRPEMTPTLARMVAGNLRNLPKPVRWFSIPNLWRYEQPGKGRLREHWQLNVDLFGVDSHRAELEILLIADSILKKFGAPIGSYQIKVSHRKLLDSFLKNSLKLNGDQVHGVSKLLDKKSKISPEAFETEMKPFLNNFKEQFSLIETYLNSNLETVSKIPGIDTNSVSFIQNLFQELGELGIDKQLLFDPSIIRGFDYYTGCIFEVFDTNPENRRSLYGGGRYDNLIGLFSKEQLSGIGFGLGDVTLKNFLEGHNLIPNLSREKTIFLPIMDESLFVDTFKLSKELRENEILTETMLDSAKIGKQIQIAEKKGYRYVLFLGESEIRTETVQIKDLISGEQKSLPRKGLSDTLKKDFQL
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.