PharMolix/UniProtQA huggingface dataset:
Protein: ERF1_PODAS
Sequence: MSDPNANEAEKNIEIWKVKKLIKRLEAARGNGTSMISLIIPPKDQISRAAKMLAEEYGTASNIKSRVNRQSVLSAITSTQQRLKLYNKVPPNGLVVYCGEILTSEGKERKVNIDFEPFKPINTSLYLCDNKFHTEALAELLESDQKFGFIVMDGNGALFGTLSGNTRDIVHKFSVDLPKKHGRGGQSALRFARLREEKRHNYVRKVAELAVQNFITNDKVNVMGIVLAGSADFKNDLNASDMFDQRLATKVIKVVDVSYGGENGFNQAIELASETLGNVKFIQEKKLIGKYFEEISQDTGRICYGVEDTLKALELGAVETLIVFENLEVTRWVLKDSNGAEIIIHSTKQQDAANRDRFMDKETGQEMEVVSQESFLEWIAEHYKDFGTTLEFVSDRSTEGNQFVKGFGGIGGILRYKVNFEQLNEVDDDDEYYDD
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, eRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBR4_DANRE
Sequence: MSRLAVVFGGSRGIGRAASKLLAQRGHRIVLLSRNKEAAQSTAQSLPGENHLGLSCDVSKEEEVQKAFETINKTCGTVGFLVNAAGINRDALLLRSKSEDMLSVLHTNLLGSMLTCKAAVRNMLSHGGAIVNIGSVVGVKGNAGQCVYSASKAGLEGFTRSLAKEVASRNIRVNLVAPGLIHTDMTAGLAEEAAVRTIPLGRFGEPAEVAQAMLFLLESPYITGQILLVDGGLQLLM
What is the function of this protein?
The heterotetramer with HSD17B8 has NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis.  Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD.  The homotetramer has NADPH-dependent quinone reductase activity.  Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o-quinones and p-quinones.
What are the official names of this protein?
Carbonyl reductase family member 4, 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit, KAR beta subunit, 3-oxoacyl-[acyl-carrier-protein] reductase, Quinone reductase CBR4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PSTS_STAHJ
Sequence: MKKWQLVGTTVLGASVLLGACGGGDSSGSGSGDGKDLKGEAKGEGSSTVAPIVEKLNEKWAKDHPNATISSGQAGTGAGFEKFIAGETDFSQASRPIKDEEKQKLEDKDIKYKEFKIAQDGVTVAVNKDNDFVKELSKDQLKKIYNGEAKTWKDVNSSWPDKKIKAFSPNSSHGTYDFFEEEVMDKEDIKAEKNGDTNVIVQSVEKNKEGIGYFGYNFYEQNKDKLKEVKIKDDKGKTTEPTKKTIKDGSYALSRPLFLYVKEKSLKDNDVMREFIKFTLEDKGKSAEDAGYVASPEKTYKDELKDLKKYDKKSDK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CYB_ERYMN
Sequence: MPHQQMLILFGLLPVATNISTWWNFGSMLLACSSMQVLTGFFLAVHYTANINLAFSSIVHITRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKKTWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHIMLLHEDGSSNPLGTNSDIDKIPFHPYHTYKDLLMLSLMVLMLLMTVSFLPDIFNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLWGALALAMSITILLTVPFTHTSTIRSMMFRPIMQLMFWTLVATFMVITWAATKPVEPPFTMISQIASTIYFLFLIMNPIAGWIENNILKYN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TYPH_ECO57
Sequence: MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: NRDR_ECO45
Sequence: MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: BSHC_CHLPD
Sequence: MNTFLLDYRQIRTPKKGFSGIFRDYVSDGHERSQLLTECFHLDAEKEGDYYKQLSLLGSRTYSRATLVDLLKRQNQRYGCSELHLKEIEKLRSPRCMVVVTGQQPGLFLGPLYTMYKALSAIVFAERQKALFPEYDFVPVFWMEIEDHDYEESAHTALFSGGKVAHFRPEPYKRLPDQMIGGSSFGEEMRNTVAEFIDTLQDSPHKEAISGLLNAAYAPGSTFETGFAQTMMHLFRDQPLILLSSQDREFKKLSRNIFARELATCPTASYNVIAQSSKLEKLGYTTQSKPRAVNLFYINTDNQRQKIELHEEDTFQIHPDKQRYSRHQILELCEDHPERFSPNVVLRPIVQDTILPVFACIAGPGEISYLAQYRKNYEHFGITMPFIIPRGSFTLIEPKFSRIMDKLLRITGKPGFSRKQIYHAVFNDLQTLKKNAEGIAEHPDIERLFNETKTEMERLLESLEPVLAKIDPTLAPVLAASSVQTLKIIESLEQKTRKAGRKKNEELLEQIQKSETAFFPEGVPQERMINSFYFINKYGPSLIGTLKNLLSGHSTEEHIIVEL
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: SINL1_ARATH
Sequence: MVKGTNAEQALAREEASSSRPKRQRVPSIVEEEGENGGGDVVVRSGTLFELDLLDCPICCNALTIPIFQCDKGHIACSSCCTNVSNKCPYCSLAIGNYRSRIMERVVEAFIVRCPIVAGEASSSRQKRLRVPSIDEENGENGGRDVVVPSGTLSQLDLLDCPVCSKALKISIFQQSLFLAKRQNGCTETFSYGNELVHEKKCSFALCYCPAPNCNYAGVYKDLYSHYAANHKKLWTRFSCGYSMHVCMDFESKSLVLQQYSDGPLVVLQCFKEPPQGLFWTVNCIAPSAPGVGKFSYELSYSTAGNTLTFRSSEMNRIQKVSFQTPEKDFMFIPEYILCPMGLYKGTYICIRSLEEEEEEEEDNED
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  It probably triggers the ubiquitin-mediated degradation of different substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase SINA-like 1, RING-type E3 ubiquitin transferase SINA-like 1, Seven in absentia-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
Protein: LIPA1_PROMP
Sequence: MTNISKNAVTKPDWLRVKAPQVERIGNTANLLSDLKLNTVCQEASCPNIGECFASGTATFLIMGPGCTRACPYCDIDFDRSKRDLDPTEPDRLAEAVFRLKLKHVVITSVNRDDLDDGGASQFYKCVSEVRKKSPETTIELLIPDLCGNWSALEKILDSRPNVLNHNIETVSALYRKVRPQGNYQRTLELLKRTREYFPSVYTKSGFMLGLGEKDDEVLTLLMDLRKNDVDIVTIGQYLSPGPKHLQVQRFVTPSKFNYFKLFGENELGFMQVVSSPLTRSSYHAEEIQKLMKKFPR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 1, Lip-syn 1, LS 1, Lipoate synthase 1, Lipoic acid synthase 1, Sulfur insertion protein LipA 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_PIPCE
Sequence: MARSLKKSPFVANHLLKKIEKLNMKGGKEIIVTWSRASTIIPTMIGHTIAIHNGKEHLPIYITDRMVGHKLGEFAPTLTFRGHARNDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SEM4A_MOUSE
Sequence: MALPSLGQDSWSLLRVFFFQLFLLPSLPPASGTGGQGPMPRVKYHAGDGHRALSFFQQKGLRDFDTLLLSDDGNTLYVGAREAVLALNIQNPGIPRLKNMIPWPASERKKTECAFKKKSNETQCFNFIRVLVSYNATHLYACGTFAFSPACTFIELQDSLLLPILIDKVMDGKGQSPFDPVHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDIFLRWLHADASFVAAIPSTQVVYFFFEETASEFDFFEELYISRVAQVCKNDVGGEKLLQKKWTTFLKAQLLCAQPGQLPFNIIRHAVLLPADSPSVSRIYAVFTSQWQVGGTRSSAVCAFSLTDIERVFKGKYKELNKETSRWTTYRGSEVSPRPGSCSMGPSSDKALTFMKDHFLMDEHVVGTPLLVKSGVEYTRLAVESARGLDGSSHVVMYLGTSTGSLHKAVVPQDSSAYLVEEIQLSPDSEPVRNLQLAPAQGAVFAGFSGGIWRVPRANCSVYESCVDCVLARDPHCAWDPESRLCSLLSGSTKPWKQDMERGNPEWVCTRGPMARSPRRQSPPQLIKEVLTVPNSILELPCPHLSALASYHWSHGRAKISEASATVYNGSLLLLPQDGVGGLYQCVATENGYSYPVVSYWVDSQDQPLALDPELAGVPRERVQVPLTRVGGGASMAAQRSYWPHFLIVTVLLAIVLLGVLTLLLASPLGALRARGKVQGCGMLPPREKAPLSRDQHLQPSKDHRTSASDVDADNNHLGAEVA
What is the function of this protein?
Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling (PubMed:20043131, PubMed:17318185).  Regulates glutamatergic and GABAergic synapse development (PubMed:29981480).  Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner (PubMed:29981480).  Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity (PubMed:15780988).  Promotes phosphorylation of TIMD2 (PubMed:12374982).  Inhibits angiogenesis (PubMed:17318185).  Promotes axon growth cone collapse (PubMed:20043131).  Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (PubMed:20043131).
What are the official names of this protein?
Semaphorin-4A, Semaphorin-B, Sema B.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: OPGH_PSEAB
Sequence: MNNPSTTKAPLADYLAHLPLAEEERERLGESASFSELHARLAGAEGAAADAGGDPALASVRARLQLGTPELDDAEMFGVDAQGRTFLKISPPIRRTKVIPEPWRTNILVRGWRRLTGRSNPPKPKRALPRARWQRVGSLRRFILLLLMLAQTSVATYYMKGILPYQGWAFVDLEELAQQSLLDTVQQVLPYVIQFGILALFAILFCWVSAGFWTALMGFWELLTGRDRYRISGSSAGSEPIAADARTAIVMPICNEDVPRVFAGLRATVESMAATGEMERFDFFVLSDTNDPDIAVAEQQAWLELCRETKGFGKIFYRRRRRRVKRKSGNIDDFCRRWGGDYRYMVVMDADSVMSGDCLAKLVRLMEANPEAGIIQTAPKASGMDTLYARMQQFATRVYGPLFTAGLHFWQLGESHYWGHNAIIRMQPFIDHCALAPLPGKGSFAGAILSHDFVEAALMRRAGWGVWIAYDLDGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFFFLVLSTALLAVHQLMEPQYFLEPRQLFPIWPQWHPEKAIALFSTTLTLLFLPKLLSVMLIWAKGAKGFGGVIRVTLSMLLEMFFSVLLAPVRMLFHTRFVLAAFLGWSVQWNSPQRDDDATPWSEAIRRHGMQTLLGIAWTLLVAWLNPRFLWWLSPIVGSLILSIPVSVISSRVKLGLRARDEKLFLIPEEYDTPRELRATDEYTYENRWHALKDGFLKAAVDPLLNALACAMGTARHNRAQAIETVRGERIGKAIEKGPEQLDGATRLALLSDPVALSRLHTRVWEEDRDDWLGRWRKAEADDPHAASVPLAQVVPGDAGLLPAAQS
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_HAEIG
Sequence: MYAVFQSGGKQHRVSEGQVVRLEKLELATGATVEFDSVLMVVNGEDVKIGAPVVAGAKVVAEVVAQGRGEKVKIVKFRRRKHSRKQQGHRQWFTEVKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: OAR2_CAEEL
Sequence: MMSSYVMSPVDETYTLFQILKGSALFLLVLWTIFANSLVFIVLYKNPRLQTVPNLLVGNLAFSDLALGLIVLPLSSVYAIAGEWVFPDALCEVFVSADILCSTASIWNLSIVGLDRYWAITSPVAYMSKRNKRTAGIMILSVWISSALISLAPLLGWKQTAQTPNLIYEKNNTVRQCTFLDLPSYTVYSATGSFFIPTLLMFFVYFKIYQAFAKHRARQIYRQKLAVSSHVIRKHIESTILHEISHVLPTSDEFAKEEEEEEDSESSGQVENGLGNGNDAIIEEDECEDEDSDEKRDDHTSMTTVTATVTGPTEAPYMKREAKISKSVPIEKESAIQKREAKPMRSVMAISYEKVKRHKNRKERIYRKSLQRKPKAISAAKERRGVKVLGIILGCFTVCWAPFFTMYVLVQFCKDCSPNAHIEMFITWLGYSNSAMNPIIYTVFNRDYQIALKRLFTSEKKPSSTSRV
What is the function of this protein?
G-protein coupled receptor for tyramine, a known neurotransmitter and neuromodulator and direct precursor of octopamine.  Expression in amphidial sensory neurons suggests a role in chemosensation.
What are the official names of this protein?
Tyramine receptor tyra-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPEH_CLOBL
Sequence: MKYSGYHLVIDLFGCNFDQLENTEYIIEMLKKLARALDTKIVAKAFHKFHPQGFSGALIISESHITIHTWPEDAYIGIDIFTCSKCFDSRKIVAYLKENLIFKKVEIKEILRGKID
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: KCY_BURP6
Sequence: MKSTRPFHPTPVITIDGPTASGKGTVAALVAAHLGFHLLDSGALYRLAALASIRYQVEPDDADALASLVDGLHITFREGCAQLDGVDVSDEIRAEAVGNRASAIAVHASVRAALVARQRAFRKTPGLVADGRDMGTVIFPDAVLKVFLTASVEARAARRHKQLMQKGFSANMDNLLQDLRERDARDSNRAAAPLKPAADAKPLDTSALTIEQSVEQVLAWYRELGQPA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_VACCC
Sequence: MTSLREFRKLCCDIYHASGYKEKSKLIRDFITDRDDKYLIIKLLLPGLDDRIYNMNDKQIIKLYSIIFKQSQEDMLQDLGYGYIGDTIRTFFKENTEIRPRDKSILTLEDVDSFLTTLSSVTKESHQIKLLTDIASVCTCNDLKCVVMLIDKDLKIKAGPRYVLNAISPNAYDVFRKSNNLKEIIENSSKQNLDSISISVMTPINPMLAESCDSVNKAFKKFPSGMFAEVKYDGERVQVHKNNNEFAFFSRNMKPVLSHKVDYLKEYIPKAFKKATSIVLDSEIVLVDEHNVPLPFGSLGIHKKKEYKNSNMCLFVFDCLYFDGFDMTDIPLYERRSFLKDVMVEIPNRIVFSELTNISNESQLTDVLDDALTRKLEGLVLKDINGVYEPGKRRWLKIKRDYLNEGSMADSADLVVLGAYYGKGAKGGIMAVFLMGCYDDESGKWKTVTKCSGHDDNTLRVLQDQLTMIKINKDPKKIPEWLVVNKIYIPDFVVEDPKQSQIWEISGAEFTSSKSHTANGISIRFPRFTRIREDKTWKESTHLNDLVNLTKS
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.  Recruits cellular topoisomerase II to sites of viral replication and assembly.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in sites viral of replication and assembly.
Protein: HEMA_INBME
Sequence: LMVVTSNADRICTGITSSNSPHVVKTATQGEVNVTGVIPLTTTPTKSHFANLKGTKTRGKLCPKCLNCTDLDVAFGRPKCMGTIPSAKASILHEVKPVTSGCFPIMHDRTKIRQLPNLLRGYENIRLSTHNVINAETAPGGPYIVGTSGSCPNVTNGNGFFATMAWAVPKNNNNKTATNPLTVEVPFICTEGEDQITVWGFHSDNEIQMVKLYGDSKPQKFTSSANGVTTHYVSQIGGFPKQAEDGGLPQSGRIVVDYMVQKSGKTGTITYQRGILLPQKVWCASGRSKVIKGSLPLIGEADCLHEKYGGLNKSKPYYTGEHAKAIGNCPIWVKTPLKLANGTKYRPPAKLLKERGFFGAIAGFLEGGWEGMIAGWHGYTSHGAHGVAVAADLKSTQEAINKITKNLNSLSELEVKNLQRLSGAMDELHNEILELDEKVDNLRADTISSQIELAVLLSNEGIINSEDEHLLALERKLKKMLGPSAVDIGNGCFETKHKCNQTCLDRIAAGTFNAGEFSLPTFDSLNITAASLNDDGLDNHTILLYYSTAASSLAVTLMIAIFIVYMVSRDNVSCSICL
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: RS17_LACDA
Sequence: MSESIERNRRHVYQGRVVSDKMDKTIVVVVDTYKNHPVYSKRTRYSKKYYAMDENNEAKVGDIVRIMETRPLSRTKRFRLVDIVKKSV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RR8_PHATC
Sequence: MVNDTISDMLTRIRNANMVKHQIVQIPASKMSLAIAEILKQEGFIGDFETYSENEKKYLLISLKYVGKLRKPVICKIERVSKPGLRVYSNSKKLPRILDNLGIAIISTSKGVMTNLKAKELGIGGEVLCYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NTCP5_HUMAN
Sequence: MIRKLFIVLLLLLVTIEEARMSSLSFLNIEKTEILFFTKTEETILVSSSYENKRPNSSHLFVKIEDPKILQMVNVAKKISSDATNFTINLVTDEEGETNVTIQLWDSEGRQERLIEEIKNVKVKVLKQKDSLLQAPMHIDRNILMLILPLILLNKCAFGCKIELQLFQTVWKRPLPVILGAVTQFFLMPFCGFLLSQIVALPEAQAFGVVMTCTCPGGGGGYLFALLLDGDFTLAILMTCTSTLLALIMMPVNSYIYSRILGLSGTFHIPVSKIVSTLLFILVPVSIGIVIKHRIPEKASFLERIIRPLSFILMFVGIYLTFTVGLVFLKTDNLEVILLGLLVPALGLLFGYSFAKVCTLPLPVCKTVAIESGMLNSFLALAVIQLSFPQSKANLASVAPFTVAMCSGCEMLLIILVYKAKKRCIFFLQDKRKRNFLI
What are the official names of this protein?
Sodium/bile acid cotransporter 5, Na(+)/bile acid cotransporter 5, Solute carrier family 10 member 5.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PPK2_NAMOO
Sequence: SPPFAPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-2, PK-2, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURT_VARPS
Sequence: MTTLGTPLSPSATRVMLLGSGELGKEVLIALQRLGVETIAVDRYENAPGQQVAHHARTITMSDPEQLKALIEAEKPTLVVPEIEAIATPMLQQLEDAGVVRVIPTARAARLTMDREGIRRLAAETLGVPTSPYKFCDSLAELQAAIDAGIGYPCIVKPVMSSSGKGQSKIDGPADVQKAWDYAMAGGRVSHGRVIVEGFIDFDYEITLLTVRAKDAAGAVQTRFCEPIGHVQVSGDYVESWQPHPMAPAALQKAQQIAEAVTSDLGGQGLFGVELFVKGDEVWFSEVSPRPHDTGMVTMATQWQNEFELHARAILGLPVDTSLKSPGASAVIYGGVDATGIAFDGVAEALRVPGSDIRLFGKPESFAKRRMGVALVHAADTGTARRLAKDAASRVKPRKA
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: MDH_ACIET
Sequence: MSKKPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLEIPDEKAQNALKGVIMELEDCAFPLLAGIEAHSDPMTAFKDTDYALLVGARPRGPGMERADLLAANAQIFTAQGKALNAVASRNVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRAASQLAAKGGFKVGDIKKLTVWGNHSPTMYADYRFATVDGKSVKDAINDQAWNKDVFLPTVGKRGAAIIAARGLSSAASAANAAIDHMRDWALGSKGEWVTMGVPSNGEYGIPAGIVFGFPVTTENGEYKIVEGLAIDAFSQECIDKTLAELQGEQDGVKHLL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: UREF_STAAM
Sequence: MIDHTHLRLFQFCDSQFPTGAFSHSFGLETYIQRNIIHDDHTFIAWLKMFLQEQLTYSDGLAMRLVYDALENDDTQKVLHIDKLMFVQNLPKETRVGAKQMGTRMVKLALELYNSPWIAWYHQQMQDKKAKLNPAICFTMLGHHLGVDIETIIDYYLYQNVSSLTQNAVRAIPLGQTAGQKIVTHMIPYIEETRKQIFELKEADFGMTAPGLELNQMAHENVNVRIFIS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_CHLAT
Sequence: MAHSVKIYDTCIGCTQCVRACPTDVLEMVPWDGCRANQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGAETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: ATP25_CANGA
Sequence: MQSLLQLKHYPLLTSYLEVLSTQKLHYMLRIRSIARPIVRRPWANAARVTGISGTRIQVPFPSSVRWYSDREPQTEPVVKDEESEHVPWYMRLEDDSLKSLNEDISKQHEVRLPDDCPDSLHILVKHLQKQLALRDILVFDLKNQRLADPENYRLKMCDYVIICTAMSTKHCERSYVEINKLLKNEYGVSGYVEGQVNPNDEKKRLKRLARKNNLGRTNIRRNALNSTEESSWYMIDCHVDSIFLNILTENRRYEMNLEELYAPLNEKHLYEKSEHSMHINTNNRSQAFDSLEEEDNVLLALRKLAQQKRQYSTESPARSLRNELVKENFDSSKKLLADNPELREQLVKVAISTIEQIRDSTGASINTEKWYKFVSHNVPLVIQDTTFWDSYLKFLLLLNDCNSQTYSYKRLIPDYLVTKRSMGEELTADDITTFLSVISERVNPQNYWDLVKANTQVVEALRLFDEEVIFTDAILSKVIKTLTTNSNEHKLHSFYEVIKFLVWKYEKEIPINTLETILKTLINFGEYDYLLRLWTTKIGYNVGSKDTRPWKVFLKAITETQDVELIRLIIEKGCLLDISRGKVDVDPQLAVLLKTAFKTVDPENLIYNDQQRLLIPSSATRQ
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.