PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_STRPM
Sequence: MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKAVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSINYDQTEIQPGDDKPNHFSFMSKDAEYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKDLIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDERWKAFEIKKNQFDNELKRLNSIKLKPVKATNDRVQELGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMIYLEGNGKAHRKY
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTF_ECOLU
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: YIBN_ECOLI
Sequence: MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGEATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDGSGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK
What are the official names of this protein?
Uncharacterized protein YibN.
Protein: YGK9_YEAST
Sequence: MAAQNPLADIQVYKRYKAKRRMEGQKKNSCTIAYIDSLQYYCRRSLSHKSCFPFPSQHAFSRPLPLSESYETWHALELAFCLTRPYCTFHSSLEISSQQLTLRPPLG
What are the official names of this protein?
Putative uncharacterized protein YGL109W.
Protein: LONM_ORYSJ
Sequence: MLRAAAAAAAVFPSRFAAAPAVAAVEEVRSPLLRVLGALRGGRVSTLGRRARFCSNSAGSDSEAAAAEAKAEDAVAAEGEADGKASSAIVPTVLRPEDCLSVIALPLPHRPLFPGFYMPIYVKDQKLLQALVENRKRSIPYAGAFLVKDEEGTDPNIVTSSDSDKSIDDLKGKELLQRLNEVGTLAQITSIQGDQVVLLGHRRLKITEMVQEDPLTVKVDHLKEKPYDKDDDVIKATSFEVISTLREVLKASSLWKDHVQTYTQHMGDFNYPRLADFGAAISGANKFLCQEVLEELDVYKRLKLTLELVKKEMEISKLQQSIAKAIEEKISGDQRRYLLNEQLKAIKKELGLETDDKTALSAKFRERIEAKKEKCPAHVLQVIEEELTKLQLLEASSSEFNVTRNYLDWLTVLPWGNYSDENFDVHHAQQILDEDHYGLSDVKERILEFIAVGKLRGTSQGKIICLSGPPGVGKTSIGRSIARALNRKFYRFSVGGLADVAEIKGHRRTYVGAMPGKMVQCLKSVGTANPLVLIDEIDKLGRGHSGDPASALLELLDPEQNVNFLDHYLDVPIDLSKVLFVCTANVIEMIPNPLLDRMEIIAIAGYITDEKMHIARDYLEKNTREACGIKPEQAEVTDAALLALIESYCREAGVRNLQKQIEKIYRKIALQLVRQGVSNEPTQEAAIVTASEEPNGGDSANKLKDETMEDPATENAAMTNADTASKEASELDLLNRTVDHDVHPAETPKEAVLTDSALSTDKLCTPEGNKDMEGAKEESADKAVEKVVIDSSNLGDYVGKPVFQAERIYEQTPVGVVMGLAWTAMGGSTLYIETTKVEEGDGKGALVMTGQLGDVMKESAQIAHTVGRAILLDKEPENLFFANSKVHLHVPAGSTPKDGPSAGCTMITSMLSLAMGKPVKKDLAMTGEVTLTGRILPIGGVKEKTIAARRSAVKTIVFPAANKRDFDELAPNVKEGLEVHFVDTYNEIFDIAFQSETQTETS
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GLNE_RHILO
Sequence: MAAVAKRTVTDWQLKPALGLAPLDQGRARQELAEIAAAAREEGLARLAKFLAGKGAGQDFLAAVFDLSPFLRDTSRRRPRILDALFDQPVEARLEAITAAIEQAPLAETVSESSLMMELRQCKAEAHFLIALADLAGEAETSLTVRRLSDLADACTRAAVDFLLRDAHGQGKLKLPDLDNPSLQSGWILLGMGKLGAHELNFSSDIDLVVFFDPDAPAVVDRLDATELFSRLTRRLVRILQDRTEHGYVFRTDLRLRPDPGSTPLAIPVEAALRYYEARGQNWERAAMIKARPVAGDLAAGAAFLRELQPYIWRKYMDYAAIADVHSIKRQIHAHKGHGEIAVKGHNVKLGRGGIREIEFFVQTQQLIAGGRFPELRGRETVPMLGQLAARGWITADARDALARQYWFLRRVEHAVQMVADEQTHTLPEDDEGLERIAHMLGFGDAAAFSQAFRASLLQVERHYAALFETAPELSAGIGNLVFTGDVDDPNTLQTLQGLGFQRPSDICRVIRGWHFGRYRVTQSAEARERLTELTPALLKAFGQTRRADEALIRFDEFLAGLPAGIQLFSLLQSNPALLKLMATIMGAAPRLAAIITRRPHVFDGLLDPALLTELPDRVYLSARLSAFLEGDRAYEEVLDRLRIFASEQKFLIGVRLLAGSIDPARAGRAFSDLADLTIEAALQAVTAEFAARHGTIAGGVVSLLGMGKLGSRELTAGSDVDLILLYDHDADAEDSDGDKPLAPSHYYTRMTQRLISAVSAPTAEGVLYELDLRLRPSGNKGPVATHIDAFKKYQRQEAWTWEHMALSRARAIGGDTGLCAEVEAEVAAVLGQPRDAAKVKTEAADMRAMIEKEKPARDLWDIKLIPGGLIDLEFIAQVAVITGQVGAGPRATGTAEILSRLAPGFADAGARQELGAAFALYLALTQMTRLCLTGSFERDDVPPGLSDLLLAVTDLPDFGVLEAHLKETSQKVRKDFDLLLRAGRP
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: SYA_FLAPJ
Sequence: MTSKEIRQQYLKFFESKGHLIVPSAPIVLKDDPTLMFNNSGMAQFKEYFLGNGTPKSPRIADTQKCLRVSGKHNDLEDVGFDTYHHTMFEMLGNWSFGDYFKKEAINWAWELLTEVYKIPKQNLYVSVFEGSKEDNVPFDQEAWDIWKGLIDEDRIILGNKKDNFWEMGDQGPCGPCSEIHVDLRTPEEKAQVSGKSLVNNDHPQVVEIWNNVFMEFNRKADGSLEKLPAQHVDTGMGFERLCMALQGKTSNYDTDVFTPLIEKVTQITGYKYTSNEVKNISEEQNKTNIAIRVIVDHVRAVAFAIADGQLPSNTGAGYVIRRILRRAIRYGFTFLDTKEPFITKLVAVLASQMGEFFPEIKSQQQLVTNVIREEEASFLRTLEQGLQLLDKVVAETKGKEVSGAKAFELYDTFGFPIDLTALILREKGYELDEAGFNAAMQEQKNRSRAASEVFTEDWSVLIPGNIETFVGYDKTENDVKITRIRKVNSKKDGILYQIVLDNTPFYPEGGGQVGDKGTLVSANDSSDSEQAKQTIDIIDTKKENNLILHFAKQLPENIETGFVAKVNTNLRASTSKNHSATHLMHLALRSILGTHVEQKGSLVNPDYLRFDFSHFSKVSDDQLRQVEASVNAQIEAQLQLTEHRNIPIKEALDKGAMALFGEKYGDNVRMIEFGESKELCGGIHVKNTAQIWHFKILSEGAVAAGIRRIEAITGDAVKAFYTNQENTLSEIKEVLKKPQDILKSVTSLQDDNVKLKKQIEQLLKEKIEGLKNTLVSEFQEINGINFLSKQVDLSMSSTKDLLQALGSLKPNSFVVLASIEENMPNIHCYIAKELVAGKGLNANVVIKELGKYIEGNGGGQPFFASGKGKNVSGIKEALQKAIEFVK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_SOYBN
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWNITGGTITNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLAGVACFGFGAFHVTGLYGPGIWVSDPYGLTGRIQSVNPAWGVEGFDPFVPGGVASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVGAGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPVFRDKEGHELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVIVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKKQVV
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CML23_ORYSJ
Sequence: MVASDEFRRVFGSFDQDGDGKISATELRLCVKASLGEDMPDEEVQALMALADTDGDGLLDEEEFVRLVTEMEADGDEEEDDDDETCRCLREAFAMYEMEGRGCITPLSLKLMLSKLGTHLDVAECQAMICRFDMNGDGVLTFDEFKTMMMA
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Putative calcium-binding protein CML23, Calmodulin-like protein 23.
Protein: TVP23_NEUCR
Sequence: MMEATPTPGSLSWRLSSHPITLLTFLAFRSSSLLVYLFGLLFTDNLVMIFIITILLLAGDFYYLKNIAGRRLVGLRWWNEVDPNSGDSHWVFESSEPGTKIINATDSRFFWLAIYAQPLLWVVLAIVALFSLKFIWLPLVAIALVLTITNSLAFSRCDKFSQASNIAGTAFSSGNIAGNIASNMVGRFFSR
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein tvp23.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: AG19_COCPS
Sequence: MKFSLLSAIAAAVFVPFTSATPLASTADLSYDTHYDDPSLPLSGVTCSDGDNGMITKGYNTAGEIPNYPHVGGAFTVETWNSPNCGKCYKVTYNAKTIFLTAIDHSNSGFNIAKKSMDVLTNGRAEELGRIKVTYEEVASSLCGLK
What are the official names of this protein?
Heat-stable 19 kDa antigen, Coccidioides-specific antigen, CS antigen, CS-AG, Precipitin antigen, TP-AG.
What is the protein family that this protein belongs to?
Belongs to the cerato-platanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AIPL1_PANPA
Sequence: MDAALLLNVEGVKKTILHGGTGELPNFITGSRVIFHFRTMKCDEERTVIDDSRQVGQPMHIIIGNMFKLEVWEILLTSMRVHEVAEFWCDTIHTGVYPILSRSLRQMAQGKDPTEWHVHTCGLANMFAYHTLGYEDLDELQKEPQPLVFVIELLQVDAPSDYQRETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLRNLQTKEKPWEVQWLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEAEAKADLRKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPTEPPAQSSTEPPAEPPPAPSAELSAGPPAETATEPPPSPGHSLQH
What is the function of this protein?
May be important in protein trafficking and/or protein folding and stabilization.
What are the official names of this protein?
Aryl-hydrocarbon-interacting protein-like 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TIG_PSEMY
Sequence: MQVSVESTSALERRMTVGVPVERIETEVNKRLQQTARRAKVPGFRPGKVPMSVIRQRYEDAARQEALGDLIQATFYEAVVEQKLNPAGAPAVEPKSFEKGKDLEYVATFEVFPEFEVTGFDSIAIERLQADVADSDVDNMLDILRKQNTRFEAVERAAENGDQLNIDFVGKIDGEAFAGGSAKGTQLVLGSGRMIPGFEDALVGVKAGEERVINPTFPEDYQNLDLAGKTAEFAVTVNSVSAPQLPELNDEFFALFGIKEGGLEGFRAEVRKNMERELRQAIKSKVKNQVMDGLLAANPVEVPKALIGNEVNRLRVQAVQQFGGNIKPDQLPAELFEEQAKRRVVLGLIVAEVVKQFDLKPDEARVRELIEEMASAYQEPEQVVAWYYKNDQQMNEVRSVVLEEQVVDTVLQKANVTDKAVSYEDAVKPAEAPKAD
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CLPX_BURA4
Sequence: MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSRSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVDTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLRETEPEDLIKFGLIPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYHKLFAMERVELEIRPGALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPAMKGVSKVIIDENVIDGDGKPLLIYEDTPKVAGSN
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: KPCZ_HUMAN
Sequence: MPSRTGPKMEGSGGRVRLKAHYGGDIFITSVDAATTFEELCEEVRDMCRLHQQHPLTLKWVDSEGDPCTVSSQMELEEAFRLARQCRDEGLIIHVFPSTPEQPGLPCPGEDKSIYRRGARRWRKLYRANGHLFQAKRFNRRAYCGQCSERIWGLARQGYRCINCKLLVHKRCHGLVPLTCRKHMDSVMPSQEPPVDDKNEDADLPSEETDGIAYISSSRKHDSIKDDSEDLKPVIDGMDGIKISQGLGLQDFDLIRVIGRGSYAKVLLVRLKKNDQIYAMKVVKKELVHDDEDIDWVQTEKHVFEQASSNPFLVGLHSCFQTTSRLFLVIEYVNGGDLMFHMQRQRKLPEEHARFYAAEICIALNFLHERGIIYRDLKLDNVLLDADGHIKLTDYGMCKEGLGPGDTTSTFCGTPNYIAPEILRGEEYGFSVDWWALGVLMFEMMAGRSPFDIITDNPDMNTEDYLFQVILEKPIRIPRFLSVKASHVLKGFLNKDPKERLGCRPQTGFSDIKSHAFFRSIDWDLLEKKQALPPFQPQITDDYGLDNFDTQFTSEPVQLTPDDEDAIKRIDQSEFEGFEYINPLLLSTEESV
What is the function of this protein?
Involved in late synaptic long term potention phase in CA1 hippocampal cells and long term memory maintenance.
What are the official names of this protein?
Protein kinase C zeta type, nPKC-zeta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Cell junction. Membrane; Peripheral membrane protein. Note=In the retina, localizes in the terminals of the rod bipolar cells (By similarity). Associates with endosomes (PubMed:9566925). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction (PubMed:7597083). Colocalizes with VAMP2 and WDFY2 in intracellular vesicles (PubMed:17313651). Transiently translocates to the membrane of CA1 hippocampal cells in response to the induction of long term potentiation (By similarity). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: RECA_FRATN
Sequence: MSKEKALESALSQIEKQFGKGAIMRLGDQEAAHDIDVIPSGIIALDVALGIGGYPKGRIIEIYGHESSGKTTLTLLAIAQCQKQGGTAAFVDAEHALDPKYAKLLGVDVDNLIVSQPDTGEQALEIADMLVRSGGVDIVVIDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTANIKRSNTLVIFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLEVKKGGSIKDGIDVSGNEIKVKVVKNKVAPPFKQADFELIYGEGISLEAELIDLGAKYNIIEKSGAWYSYKGKKIGQGKEKSKEYLKENTAERDEIERAILELLLPNKYPNKDSNDSPKEGSKIKTKVNPAVTQDELI
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_ECOL5
Sequence: MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSMQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RL7_PROM4
Sequence: MSKKTDEILDSLKSLSLLEASELVKQIEEAFGVSAAASAGVVMAAPGAGGGASAAGEAAEEKTEFDVILESFDAAAKIKVLKEVRNATGLGLGEAKAMVEAAPKTIKEGASKEDAEALKKAIEAVGGKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SRBS1_MOUSE
Sequence: MSSECDVGSSKAVVNGLASGNHGPDKDMDPTKICTGKGTVTLRASSSYRGTPSSSPVSPQESPKHESKSGLEPEDPSADEWKLSSSADTNGNAQPSPLAAKGYRSVHPSLSADKPQGSPLLNEVSSSHIETDSQDFPPTSRPSSAYPSTTIVNPTIVLLQHNRDPASERRAGEQDPVPTPAELTSPGRASERRAKDASRRVVRSAQDLSDVSTDEVGIPLRNTERSKDWYKTMFKQIHKLNRDDDSDVHSPRYSFSDDTKSPLSVPRSKSEMNYIEGEKVVKRSATLPLPARSSSLKSSPERNDWEPLDKKVDTRKYRAEPKSIYEYQPGKSSVLTNEKMSRDISPEEIDLKNEPWYKFFSELEFGRPTNLEKDLSFCQAELEADLEKVETVNKSPSANSPQSSAVSPTPDITSEPPGYIYSSNFHAVKRESDGTPGGLASLENERQIYKSVLEGGDIPLQGLSGLKRPSSSASTKVDRKGGNAHMISSSSVHSRTFHTSNALGPGCKHKKPLSAAKACISEILPSKFKPRLSAPSALLQEQKSVLLPSEKAQSCENLCVSLNDSKRGLPLRVGGSIENLLMRSRRDYDSKSSSTMSLQEYGTSSRRPCPLSRKAGLHFSMFYRDMHQINRAGLSLGSISSSSVRDLASHFERSSLTLARGELGASQEGSEHIPKHTVSSRITAFEQLIQRSRSMPSLDFSGRLSKSPTPVLSRSGLTSARSAESLLESTKLRPREMDGMDSGGVYASPTCSNMADHALSFRSLVPSEPLSICSDELDHCSNVSNDSREGSGGSVHGDFPKHRLNKCKGTCPASYTRFTTIRKHEQQSSRQSDWRSDSRGDKNSLLRNIHLMSPLPFRLKKPLQQHPRQPPPSDSSESPAGQKADLPCHDPQDQPHSAGKPQVPTRLSSRHTMARLSHNSEPPLDRPAGLEDCTRAINNGNPVPYSDHGLDRNNNPQSELAAAHGDSESPRHFIPADYLESTEEFIRRRHDDKEKLLADQRRLKREQEEADIAARRHTGVIPTHHQFITNERFGDLLNIDDTAKRKSGLEMRPARAKFDFKAQTLKELPLQKGDVVYIYRQIDQNWYEGEHHGRVGIFPRTYIELLPPAEKAQPRKLAPVQVLEYGEAIAKFNFNGDTQVEMSFRKGERITLLRQVDENWYEGRIPGTSRQGIFPITYVDVLKRPLVKTPVDYIDLPYSSSPSRSATVSPQQPQAQQRRVTPDRSQPSLDLCSYQALYSYVPQNDDELELRDGDIVDVMEKCDDGWFVGTSRRTRQFGTFPGNYVKPLYL
What is the function of this protein?
Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor.  Required for insulin-stimulated glucose transport.  Involved in formation of actin stress fibers and focal adhesions.
What are the official names of this protein?
Sorbin and SH3 domain-containing protein 1, Ponsin, SH3 domain protein 5, SH3P12, c-Cbl-associated protein, CAP.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell membrane. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Nucleus matrix. Note=Colocalized with PXN at focal adhesions during myogenic differentiation (By similarity). Colocalizes with actin stress fibers. Also detected at the plasma membrane and in neuronal intranuclear inclusions. Colocalizes with the Ten-1 ICD form of TENM1 in the nucleus.
Protein: FKBP4_GIBZE
Sequence: MSAVPGPVYGLEVPPGEILIPAAMEFPASSLSVAGASFATPLVLPAGDLNSNQKILQFRITMAAVDPTEEPEADGEGNIPTVPRSTLRLVKRALPGLEDEDDEIDDEYMKALLAGSDDEEDSDEEANGGPSDPAKAKKQRQAAAIKKLLESAQEESDEEMEDAKPNGKAKGKAKATEESDDDEDEDSDDDSEEGADLENFVICTLDTERNYQQPLDITVNHGEKVFFVVTGSHTIYLTGNYIMDDDEDDEDSEDEDEYDLSPDELEYGLEGDDSDASDDLDGLEDPRVEEIDTDEEEAPKLVAANKGKNKRAAEEAAGLDELITKEDAKLSKKQQKKLKNNKGEAVAAEEKKDAKKVQFAKNLEQGPTGSTTEKPKQAKDSKPATGVKVVQGVTVDDRTVGNGRTVKSGDTVGVRYIGKLQNGKQFDANKKGKPFSFKAGKGQVIKGWDIGVIGMAIGGERRLTIPAHLAYGSRGLPGIPANSTLIFDVKLLEIK
What is the function of this protein?
PPIase that acts as a histone chaperone.  Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail.  Proline isomerization influences H3 methylation thereby regulating gene expression.
What are the official names of this protein?
FK506-binding protein 4, Histone proline isomerase, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXS_HALMA
Sequence: MTEETDLEDLRRGTDLVKRGFAKMQKGGVIMDVVNREQARIAEDAGAVAVMHLESVPADIRKRGGVARMADPSKLEEIIEEVSIPVMGKARIGHTAEAQILEAAGADMVDESEVLTQADDRYHIDKREFTAPFVCGARNLAEALRRIDEGAAMIRTKGEAGTGDVNQAVTHQRNIQRSIGKLEGMAYEERDEWAREHGAPRRLVHETADRGRLPVVNFAAGGIATPADAALMMQHGCDGIFVGSGIFGAENPQAMGESVVAAVNNYDDPEQLKEIAKNPGKGMKGQANADLDEEEQLQGRGV
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: THIO_STAA3
Sequence: MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: SYY1_BACCZ
Sequence: MGILQDLEFRGLINQQTDAEGLEQLLEKESVKLYCGFDPTADSLHIGHMLPVLMLRRFQLAGHQPIALVGGGTGMIGDPSGKKAERTLNTKDTVAYYTESIKNQLSNFLEFENVENPATMANNYDWLGNLDVISFLRDIGKNFGLNYMLAKDTVASRLETGISFTEFSYMILQSYDFLNLYQHHNCRLQIGGSDQWGNITAGLELIRKSEEDAKAFGLTIPLVTKSDGTKFGKTEGGAIWLDPEKTTPYEFYQFWINTDDRDVVKYLKYFTFLSHEEILELEKQVAEAPEKRAAQKALGAEMTKLVHGEEALEQAIKISAALFSGSVAELTASEIEQGFKDVPSVERTAEDTVLIDLLVESKISPSKRQAREDVTNGAIYVNGERTQALDYVVTEKDRIEGKFTIIRRGKKKYFLIRY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase 1, Tyrosyl-tRNA synthetase 1, TyrRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPT3_NICPL
Sequence: MAGYRADDEYDYLFKLVLIGDSGVGKSNLLSRFTKNEFNLESKSTIGVEFATKSLNIDNKVIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDVTRHVTYENVTRWLKELRDHTDPNIVVMLIGNKSDLRHLVAVSTDEAKGLAEREGLYFMETSALEATNVENAFTEALTQIYRIVSKKAVEAGDEGATSSAPPKGETINIKDEGSSWKKFGCCSS
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein YPT3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: MSRA_ECO27
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLHGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRRITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TRPC_ALKCK
Sequence: MLEKILATKREEISQLQLPEKQYFPKKSLKASLQKTSLPLGLIAEIKQASPSKGVLCETISPTAIARVYEEGGASAISVLTDRTYFQGDTAYVAEVKKTVSLPVLRKDFILSPLQVEETACIGADAMLLIAGAMEAKQLHELYELAYSKGLECLVEVHSEEELESLLAVFTPEVIGINNRNLKTFQTSVSQTEQIAKMVPKEALLVSESGIHTPDDIARVKKAGANAVLIGEQLMRKDDKRQAIIDLFSESAINQ
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.