PharMolix/UniProtQA huggingface dataset:
Protein: BETB_PSEPG
Sequence: MARFGTQKLYIDGAYVDAGSDATFEAINPATGEVLAHVQRATEADVEKAVESAERGQKVWAAMTAMQRSRILRRAVDILRERNDELAQLETLDTGKSYSETRYVDIVTGADVLEYYAGLVPAIEGEQIPLRESSFVYTRREPLGVTVGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGLPNGVFNVLTGSGREVGTWLTEHPRIEKVSFTGGTTTGKKVMASASSSSLKEVTMELGGKSPLIICADADLDKAADIAMMANFYSSGQVCTNGTRVFIPAEMKAAFEAKIAERVARIRVGNPEDENTNFGPLVSFAHMENVLSYIAKGKEEGARVLCGGERLTEGEFAKGAFVAPTVFTDCSDDMTIVKEEIFGPVMSILSYETEEEVIRRANDTEYGLAAGVCTNDITRAHRIIHKLEAGICWINAWGESPAEMPVGGYKQSGVGRENGVSSLAQYTRIKSVQVELGGYNSVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: BAG6_DANRE
Sequence: MEESGVIEVTVKTLDSQSRTFTVRGEWTVKQFKEHIAASVEISVDKQRLIYQGKVLQDERTLTEYNVDGKVIHLVERPPPQSSQPGGGGGGVSGSSGAADGGSSSSQSSAYTTSHDRNANNYVMLGTFNLPVNIMDPQQIQMSVQQMLAGVGEMGRNVRVSTSTGSSGSVDVHINVDQSVQSEPRMRLHLAENLLRETQALIHRLEGQSSEPSQQETPPPQPSSSSFSAHPMDSSPPPPSVSSSASQTEGETQSGPNHPSPLELVEVLSEVRRVEERLRPFMERTHSILGAATSADYNNNTQEREEDQRTLNLIGESLHLLGNTLVALSDLRCNLSAQPPRHLHVVRPMSHYTSPVMMQSGLPHIPIPMNLGSTVTMTSNSRQTSDGQPQPPHSSNQSDQQGQAPPTPANESNQQTGHGQGTPRVIRITHQTMEPVVMMQMNLDGTTVPLHVPGLPPEFMQAIMHQISQQAVTMATAASAGHQGQQQGTAGAGAQNGESPVPPPPQARVVITRPTLSPRVPQPMGTRGTTINLRAAVPPPSGQQTNQMVSGLVGQLLLPLHTGDQTSTTSSSHSFSFSTSSSTSSSSSFSSASPPLSSANTSGQTSTHTTSTASVGQAQESGPGDNLAQLLGSLLGGAAGAGGGVSGATPSITVTVPGVPAFIQGLSEFIQSGQPVFPSPNQQPPPSQATPPSAPSGPAPTTAPSGGAETLSPELFTGIVQGVLSTMMGSLGAGQGNTESIAQFIQRLSQTSNLFTPGAGDAVGFFGDLLSLVCQSFSMVDMVLLLHGNPQPLSRIQPQLTAFFTEHYLQGREPTDANIASASEDLINELEEYIAESFSTVTVREGVDIIQTNMSFLRQQFTRMATHILRCTDNTFGQRLLYLCTQGLFECLALNLYCLRGEQRALTTVINHRIRRMSAEVNPSLVNWLTSMMSMRLHVILEHNPVTEDQIQHYVIYTQSESARRTEAGSQSSQQSQNMNVEEGLSPAPATTAEEALRSTGDTDGDEAPGRPSAEETRGAVAMATTEREESTGEAEPWAATVPPEWVPIIRRDMLTQRKMKAQPPLSDAYMHGMPAKRRKTAQGEGPHLSLTEAVSRAARTAGVRPVTAPDSLQGELETPELQEAYAQQVKSDIKKRLSDDPDYNHQRFPNTHRVFSEDA
What is the function of this protein?
When nuclear, may also act as a component of some chromatin regulator complex.
What are the official names of this protein?
Large proline-rich protein BAG6, BCL2-associated athanogene 6, HLA-B-associated transcript 3.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Secreted, extracellular exosome.
Protein: HSLO_CYAP4
Sequence: MADQLIRATAAEDGIRAVGVITTRLTEEARQRHKLSYVATAALGRTMAAGLLLASSMKQPQARVNIRIKGDGPLEGLFVDAGCDGTVRGYVYNPAIELPPNAKGKLDVGGAVGSQGYLYVIRDLGYGYPYSSTVELVSGEIAEDITHYLVTSEQTPSALVLGVFVTEAGVTAAGGVLIQVLPKAAQDEALVEKLESRISALSGFTPLLQRGLSLSEIFEQLLGDMGLTILPQRQLVRFHCRCSFDRMLGALKILGSDELQDMIDRDNGAEATCHFCGEVYQASSEQLAELIDELKAEAGG
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_HYDCU
Sequence: MNEEVSRPTRVALEIRKTLMEILHRDTKDPRLEKVNITECKISKDLSIATVYFTIIGVNEKDQPAQDAIKALEKAKGFFRSEIGKRMNLRITPEVRFFYDTVAENASHIEELIFKALHQKK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG27_PICAN
Sequence: MLHLITPLLLLLARFSMAIDISDEHFSAYPRMKELIGSHLVSRTEETPPSTKKITWYLKITDSGSGSPKDDTFPSECPKDSQLCGLTEISLPNRDPVITEVFSFSNKLTPQFDVNTSSFIVNLRGANWGAYTLDAEIEFVCASDDNAEGLKLVKFDYSTVSLQYKTSSACKSNETPPKDGKNKAPKDDDSNSWGVFTWLFILLVIVMASYIIAQAWINANRVGSSHEFLNELVESIVETLTKLPEFLREIANKLFTSGSRGGYSAV
What is the function of this protein?
Regulates the cytoplasm to vacuole transport (Cvt) vesicle formation.
What are the official names of this protein?
Autophagy-related protein 27.
What is the protein family that this protein belongs to?
Belongs to the ATG27 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Cycles among the pre- autophagosomal structure (PAS), mitochondria and Golgi.
Protein: GLPK_STRR6
Sequence: MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAGWVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAIVWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGELLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEVRSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYARDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDIIDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGLSVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: NLTP_CORAV
Sequence: MGSLKLVCAVLLCMMVAAPVARASLTCPQIKGNLTPCVLYLKNGGVLPPSCCKGVRAVNDASRTTSDRQSACNCLKDTAKGIAGLNPNLAAGLPGKCGVNIPYKISPSTNCNNVK
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein Cor a 8.0101, nsLTP Cor a 8, Allergen Cor a 8, Lipid transfer protein Cor a 8, LTP Cor a 8.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: ARBH_ASFM2
Sequence: MEGEELIYHNIINEILVGYIKYYMNDISEHELSPYQQQIKKILTYYDECLNKQVTITFSLTNAQEIKTQFTGVVTELFKDLINWGRICGFIVFSARMAKYCKDANNHLESTVITTAYNFMKHNLLPWMISHGGQEEFLAFSLHSDIYSVIFNIKYFLSKFCNHMFLRSCVQLLRNCNLI
What is the function of this protein?
Suppresses apoptosis in host cell to promote the viral replication (By similarity).  Has the ability to potentially bind to all the members of the proapoptotic Bcl-2 family (By similarity).  Inhibits autophagy by interacting with host Beclin 1 (BECN1) (By similarity).
What are the official names of this protein?
Apoptosis regulator Bcl-2 homolog.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Host mitochondrion. Host endoplasmic reticulum.
Protein: TM59L_BOVIN
Sequence: MDSVALMPLLLLLLLQPPPATPAPPVRDPFALQLGDTQNCQLRCRDRYPKPQLAQEELGEDPIQSRRAKAYDRAVLTSACERGCRLFSICRFVARSSKPNATQAECEAACVEAYVKETEQQACSEGCWSQNPEPEPEPELEQKRKVLEAPSGALSLLDLFSTLCNDLVNSAQGFVSSTWTYYLQTDNGKVVVFQTQPVVESLGHEGARLQRVEVTWRGSHPEALEVHVDPVGPLDKVRKAKIRVKTSSKAKVESDELQDNDFLSCMSRRSGLPRWILACCLFLSVLVMLWLSCSTLVTAPGQHLKFQPLTLEQHKGYMVEPEWSLYPPPSHAYADSPPPYKLKLDLTKL
What is the function of this protein?
Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP.  Inhibits APP transport to the cell surface and further shedding (By similarity).
What are the official names of this protein?
Transmembrane protein 59-like.
What is the protein family that this protein belongs to?
Belongs to the TMEM59 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type I membrane protein.
Protein: GRPE_CUPMC
Sequence: MEEQNQTPTPNTQAAEDAARTPEAGADEVGRLTQQVAELEAKAKEHYDMFLRATAEGENIRRRSQDEVAKAHKFAIESFADNLVPVMDSLQAALADGTGDLGKLREGVELTARQLAAAFERGRIVEVNPVGEKFDPHRHQAISMVPSEQEPNTVVNVLQRGYMIADRVLRPALVTVSAPR
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC5D2_ARATH
Sequence: MAATMADYNDQIVNETSFYNRMVLSHLLPVNLWEPLPHFLQTWLRNYLAGNILYFISGFLWCFYIYYLKLNVYVPKESIPTRKAMLLQIYVAMKAMPWYTLLPAVSEYMIEHGWTKCYSTLDHFNWFLCFLYIALYLVLVEFMIYWVHKELHDIKFLYKHLHATHHMYNKQNTLSPFAGLAFHPLDGILQAIPHVIALFIVPIHLITHLSLLFLEGIWTASIHDCIHGNIWPIMGAGYHTIHHTTYKHNYGHYTIWMDWMFGSLMVPLAEKDSFKEKEK
What are the official names of this protein?
Putative Delta(7)-sterol-C5(6)-desaturase 2, Delta(7)-sterol-C5-desaturase 2, Delta-7-C-5 sterol desaturase 2, Homolog of DWF7 protein.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CHDC_STRCO
Sequence: MSDDASTPAAERIPNKGKLAKDLNEVIRYTLWSVFKLKDTLPEDRAGYADEVQELFDQLAAKDVTIRGTYDLSGLRADADLMIWWHAETADQLQEAYNLFRRTKLGRALEPVWSNMALHRPAEFNRSHIPAFLADETPRNYISVYPFVRSYDWYLLPDEDRRRMLADHGKMARGYPDVRANTVASFSLGDYEWILAFEADELHRIVDLMRHLRGSEARRHVREEIPFYTGRRKDIGELVAGLA
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 2 subfamily.
Protein: PCP4_HUMAN
Sequence: MSERQGAGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS
What is the function of this protein?
Functions as a modulator of calcium-binding by calmodulin.  Thereby, regulates calmodulin activity and the different processes it controls (PubMed:19106096, PubMed:23204517, PubMed:27876793).  For instance, may play a role in neuronal differentiation through activation of calmodulin-dependent kinase signaling pathways (PubMed:21491429).
What are the official names of this protein?
Calmodulin regulator protein PCP4, Brain-specific polypeptide PEP-19, Purkinje cell protein 4.
What is the protein family that this protein belongs to?
Belongs to the PCP4 family.
Protein: LG3BP_RAT
Sequence: MALLWLLSVFLLVPGTQGAKDGDMRLVNGASASEGRVEIFYRGRWGTVCDNLWNLLDAHVVCRALGYENATQALSRAAFGPGKGPIMLDEVECTGNESSLANCSSLGWMVSHCGHEKDAGVVCSNDSRGIHILDLSGELPDALGQIFDSQQDCDLFIQVTGQGHGDLSLCAHTLILRTNPEAQALWQVVGSSVIMRVDAECMPVVRDFLRYFYSRRIEVSMSSVKCLHKLASAYGATELQGYCGRLFVTLLPQDPTFHTPLELYEYAQATGDSVLEDLCVQFLAWNFEPLTQAEAWLSVPNALIQALLPKSELAVSSELDLLKAVDQWSTATGASHGDVERLVEQIRFPMMLPQELFELQFNLSLYQGHQALFQRKTMEALEFHTVPLKVLAKYRSLNLTEDVYKPRLYTSSTWSSLLMAGAWSTQSYKYRQFYTYNYGSQSRYSSYQNFQTPQHPSFLFKDKLISWSATYLPTIQSCWNYGFSCTSDELPVLGLTTSSYSDPTIGYENKALILCGGYSVVDVTTFIGSKAPIPGTQETNSSKTPSLFPCASGAFSSFRVVIRPFYLTNSTDTE
What is the function of this protein?
Promotes integrin-mediated cell adhesion.  May stimulate host defense against viruses and tumor cells (By similarity).
What are the official names of this protein?
Galectin-3-binding protein, Cyp-C-associated protein, CyCAP, Lectin galactoside-binding soluble 3-binding protein, Mac-2-binding protein, MAC2BP, Mac-2 BP, Protein 90K.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space, extracellular matrix.
Protein: PNP_PSELT
Sequence: MKTWKREILGREFIVEHGKVAKQANGAVVARIGDTTVLATAVMSDSAVEGIDFVPLTVEFQERFYAAGKIPGGFIKREGKPSEMAILSARTIDRPIRPLFPKHLRNEVQVVVTVISTDSVNTPDIVGVFAASLALNISDIPFNGIVAAVRVGLVDGKIVLFPTEDQLQKSLLDIVVAGTEDTITMVEGEAKEVSESQMLQALLKAHDAIKQIIDFEKEILSYFNIEKAQIAEKTLPEEIEKEFSQLLDGNELRERLLIQGKKARSNALSEYFKKIYEILEARYGTEKIEELSVLLKDKYEEALKYKMRRIIVEEGTRLDMRKPKDIRPITCETGLLPRVHGSALFTRGETQSLGIVTLGAPMDEQIIDSLLEEGTKRFMLHYNFPPFSTGEVKPLRGPSRREIGHGHLAERALKFVLPDEDRFPYTIRIVSEILESNGSSSMATVCSGSLALMDAGVPISKHVAGVAMGLILEKDSQIVLTDILGAEDHWGDMDFKVAGTRDGITAFQMDCKVSGVSADLLERALNQAKEARLYVLEKLYETISKPRDTLSKYAPVIKVISIDPSKVAEIIGPGGKIIKALIKDYDVKISVDDLTGKVSVIGGNEEKVDAAIEQINSILKEISVGDVFSGKVTRIEPFGVFVEISPGKVGLLHQSKLITDLKTVKIGETMRVKVSNIDNLGRLQLEEFSDSPDHKHGEKRSFKRHRKNDN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_CLOK5
Sequence: MAKKVVVGMSGGVDSSVAAHLLKEQGYEVIGVTMQVWQEDDYYEDMESGCCSLSAVEDAKMVAYHLNIPHYVMNFKEAFKKNVIDYFIQEYMEGKTPNPCIACNKYIKFDELLKRAMDLGADYVATGHYATVEKINDRYTLRKSKDHNKDQTYALYNLTQFQLAHTLMPCGIYKKEEIREIAREIGLMVHSKRDSEEICFIPDNDHGAYIKRITKDKVKEGNFIDKEGNVLGKHKGIVYYTLGQRKGLGLSFGVPTYVIDIKPYTNEVVLGSEEDIFKTDLVAKDVNFLPFENLTSPMKVEAKIRYSSKPAEATISCLDEERIKVKFTDRQRAITKGQSVVFYKDNILIGGGIIDS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_CHRVO
Sequence: MSKPRSNRRHIDGVLLIDKPYDISSNNALQKARWLLNAAKAGHTGVLDPLATGLLPVCLGEATKFSSYLLDADKGYRATVRFGVVTTTGDVEGEVVSERPVEFGREQLEAALARFRGEISQVPPMYSALKHQGKPLYEYARAGIEVPREARQVTIRKLELLSFDGVSAEIDVLCTKGTYIRTLGCDIGEALGCGAHLTALRRTATGGFSLDESHRLADLESLDMPAREALLMPADVLVMHFPQLELADEEIGKFLHGQPVRFEQKCEKMQRFRVYQQSSRRFVGLGEARGDGRLHPIRLLANQAQA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: F16PA_CYTH3
Sequence: MERNLSTVKTLVQFITESQKHVFGASGDLSKILNDIAVAAKIINREVNKAGLLDILGMEGGMNVQNEEVKKLDVYANDQFISALRSGGQCCAIASEENTDIIPIENNGHSKSNYVVLIDPLDGSSNIDVNVAIGSIFSIYRRVSESGPGETVDCMQVGNKQVAAGYIIYGSSTMMVYTTGDGVNGFTLDPSIGEFCLSHPNLKIPEDGFIYSVNEGNYADFPREIQEYIYYCKTPDFETSRPYSSRYIGSMVADFHRNLIKGGIFMYPATAKYPLGKLRLMYECNPLAFIVEQAGGKAIDGEGRILDIEPTNIHQRTGIIIGSKNMVEKVEAFIQMNVGLNVYRLK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPA_BACSU
Sequence: MANNNSGNSNNLLVPGAAQAIDQMKLEIASEFGVNLGADTTSRANGSVGGEITKRLVSFAQQNMGGGQF
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
What are the official names of this protein?
Small, acid-soluble spore protein A, SASP.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: THIG_SALRD
Sequence: MSDVTHANGAVANEADDALVIGDHSFSSRILVGTSRYPNPQVMLDALEATGTELVTVAIRRVNIENPAPESHLDLLRRGGYEVLPNTAGCYTAREAVLTARLAREALGTDLLKLEVIGDDETLMPDVEQLLDAAKTLVDDGFTVLAYANDDPITCRKLADLGCAAVMPLGSPIGSGMGIVNPYNLRIIREMIEDTPLIVDAGIGTASDAVTAMELGYDGILVNTAIAQAQHPVDMGRAMRKAVEAGRSAHRAGRIPRRLYAEASSSMEGRIGT
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_VARPS
Sequence: MTLTLGHFLSLGAMLFALSVIGIFLNRKNLIVLLMAIELMLLAVNMNFVAFSYYLGDMHGQIFVFFILTVAAAESAIGLALLVLLFRNKSNINVDELNSLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YNW8_YEAST
Sequence: MVWCHYILLVLTFFLFTTFFTAACPAIFTWLNSLFRLSNDSPHVVHTSIAEVGDIEDGRVDKDGVLFVDLEFFLGCLPFFFFALVDQSSSSSVCKPLSPSDAKRSSNSLLRLSLVSSNDSDSSVSVSTFAFFFFFLFFLFFVFTCTFSSELTSSTSISISMLRLSSSLSSSEDDSASFLSISASSACNACRSISSFSLTLSSAESNFSRSERLSNPSVMFSSSISFRISSIFFLCSLVFMWFFNCFSDLNVLLQIKHS
What are the official names of this protein?
putative uncharacterized membrane protein YNL228W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NAGB_BACHK
Sequence: MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSIMKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIADEHRQVFTISDLLSDSRVGETAN
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: DAF9_CAEEL
Sequence: MHLENRVLSSVLDYASKFYKRMSSLVFFSANSIQVQMNISQSSWIKCRDWMAFALSHHIIMGIYLLILRNFLPQVVPDFEWQHYFMRVFIVHIIYIIISYFIRITRYPPGPPPMAVFGNSPFVNILTPEQTFLEYREIYGPIFTLHLSQPTIILAEYKTIQEALVKNGQQTSGRSSAESFVLFTGDRLNGDGVILAMRQKWKDMRHEISRFMNKWYGAPMDELVLHHTRCLEQELAKIAETKSLIDLRDPLAGAIANVIQQITIGRNYMYQDQEFQTQLRDINAVVKEIMTAEVFFVNCYPWLRYLPEGILRKWTNYKRSGFRLQQWFRTILEEHHVNRHQGDFMSHMIDLQESKQEQFRDLSIILTCGDMWTGGMETTVTTLRWGIIYLLNNPEVQAKCQMEILDVFGNDIPDMGKMNQTPYVRATLSEIQRLANVLPWAIPHKTIEECNIGGYDIPVNTEIIPALGAVLFDPNVFESPKQFKPERFLDEEGKYRVMEEFRPFGLGPRVCLGERIARTELYLIFASLLQNFRFYLNRGDPIPVAERVIGGITAPPKPYATRVEYLGNRLIN
What is the function of this protein?
Converts the 3-keto steroids 4-cholesten-3-one and lathosterone into the carboxylic metabolites 3-keto-4-cholestenate (Delta(4)-dafachronic acid, Delta(4)-DA) and 3-keto-7,(5a)-cholestenate (Delta(7)-dafachronic acid, Delta(7)-DA) respectively, by catalyzing successive oxidations at C-26 (PubMed:16529801, PubMed:22505847).  Dafachronic acids bind directly to the nuclear hormone receptor (NHR) DAF-12, suppressing dauer formation and inducing reproductive growth (PubMed:11782415, PubMed:12783794, PubMed:16529801, PubMed:22505847).  In a non-cell autonomous manner, negatively regulates body wall muscle arm extensions to motor neurons probably by preventing daf-12 isoform b activation (PubMed:18436204).  May be involved in thermotolerance (PubMed:24957743).
What are the official names of this protein?
3-ketosteroid oxygenase, Cytochrome P450 daf-9, DAF-9.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Localizes to dendrite-like structure in XXXL/R cells.
Protein: RS7_ROSS1
Sequence: MPRRGTIERRIPPPDPRYNSVLVQQFINKVMQRGKKSIAEKIVYQAFDLAAQRLKKPALEIFETAVRNAGPVIEVKPRRVGGATYQVPVEVKSDRRQSLAMRWLLMSARARSGKPMYERLAAELIDAYNNTGATIKRKEDVQRMAEANRAFSHYGRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: LOX3_ARATH
Sequence: MALAKELMGYPLITERSSLVSSASHFKKRTQSTQFSINPFDRRPRKTKSGVVAAISEDLVKTLRFSTTTGDRKSEEEEKAAVKFKVRAVVTVRNKNKEDLKETLVKHLDAFADKIGRNIVLELISTQLDPKTKLPKKSNAAVLKDWSKKSKTKAERVHYTAEFTVDAAFGSPGAITVMNKHQKEFFLESITIEGFALGPVHFPCNSWVQSQKDHPDKRIFFTNQPYLPNETPSGLRVLREKELKNLRGDGSGVRKLSDRIYDFDVYNDLGNPDKSSELSRPKLGGKEVPYPRRCRTGRQSTVSDKDAESRVEKPLPMYVPRDEQFEESKQDTFAAGRLKAVLHHLIPSLKASIVAEDFADFGEIDRLYKEGLLLKLGFQDDIFKKFPLPKVVVDTLQESTKGLLKYDTPKILSKDKNAWLRDDEFARQAIAGINPVNIERVKTFPPVSNLDPKIYGPQHSALTDDHIIGHLDGFSVQQALEENRLYMLDYHDIFLPFLDRINALDGRKAYATRTIFFLTRLGTLKPVAIELSLPPHGPKHRSKRVLTPPVDATSNWMWQLAKAHVSSNDAGVHQLVNHWLRTHACLEPFILAAHRQLSAMHPIFKLLDPHMRYTLEINALARQSLISADGVIEGGFTAGAYGMEMSAAAYKSSWRFDMEGLPADLIRRGMAIPDATQPHGLKLLIEDYPYANDGLLLWSAIQTWVRTYVERYYPNPNLIKTDSELQSWYSESINVGHADLRDADWWPELSTVDDLVSILTTLIWLASAQHAALNFGQYPYGGYVPNRPPLMRRLIPDESDPEYASFISHPEKYYFSSMPSLAQTSKFMAVVDTLSTHSPDEEYIGERQQPSIWTGDAEIVEAFYGFAAEIGRIEKEIEKRNADPDRRNRCGAGVLPYELLVPSSEPGVTCRGVPNSVSI
What is the function of this protein?
13S-lipoxygenase that can use linolenic acid as substrates.  Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).
What are the official names of this protein?
Lipoxygenase 3, chloroplastic, AtLOX3.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.