PharMolix/UniProtQA huggingface dataset:
Protein: SYT_LACGA
Sequence: MSFSVTLPDGSKKDFDKAVSVKELASSIATSLGKAAVGAKINGEMKPLDYVVDEDVEAAIITDKDEEGLNILRATAAFLLEAIAKRKYPELRLGMHEADEGGFFVDTDKEDQIKITELPELEKEMQKAIKNGEKIEYTSMKKSELEDIFKDDQFKLDLLKDEKDEVAVYKLGDFVDFGFEALLPNTGKIKNFKLLSVAGAYWLGKSSNPMLQRIFGTAFFKKAALDEDLKRRAEIKERDHRTIGRDLDLFFVDPKVGAGLPYWMPKGATIRRVVERYIVDKEVADGYEHVYTPVLMNVDAYKTSGHWAHYRDDMFPPMDMGDGEMLELRPMNCPSHIQIYKHHIRSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVALDQIREEFAKVLKLIMDVYKDFDITDYYFRLSYRDPKNTDKYYANDEMWEKSQSMLKAAMDDLGLDYVEAEGEAAFYGPKLDIQTKTALGNDETMSTIQLDFMLPERFGLTYVGQDGEEHRPVMIHRGIVGTMERFIAYLTEIYKGAFPTWLAPVQAEIIPVNEEAHGAYADKVREELAKRGFRAEVDHRNEKLGYKIRESQTQKVPYTLVLGDDEMNANGVNVRRYGTEEQISKSLDDFIAEIDADVKSYSREK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOD_BUCAI
Sequence: MDQNPQSQLKLLVTHGKEQGYLTYSEVNDHLPEDIIDSEQIDDIIQMINDMGIPVVEEAPDADDLILNEINTDTDEDAVEAATQVLSSVESELGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEEGINQVQCSVSEYPEAITYLLEQYDRVKTGQIRLSDIITGFVDPNAEEIFPPTAIHIGSELLDEQQNNEEDEENNQEDHEDDHSIDPELANEKFSELRIQYNNTNNTIKNKNRTHKDSLLEIYNLSEVFKQFRLVPKQFDHLVNNMRHMMERVRKQERIIIKLCVEICKMPKKNFIKIFPIKKINYLWFIREQNTNQPWSENLKKVKEDVFISVKKLIKIEEETGLTIEQVKDINKRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEIGREPTPEELSEKMLIPEDKIRKVLKIAKEPISMETPIGDDDDSHLGDFIEDTTLELPLDSATSESLRSATHDVLSGLTAREAKVLRMRFGIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor RpoD, Sigma-70.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMOB_METCA
Sequence: MSVNSNAYDAGIMGLKGKDFADQFFADENQVVHESDTVVLVLKKSDEINTFIEEILLTDYKKNVNPTVNVEDRAGYWWIKANGKIEVDCDEISELLGRQFNVYDFLVDVSSTIGRAYTLGNKFTITSELMGLDRKLEDYHA
What is the function of this protein?
The B protein acts as a regulator of electron flow through the soluble mmo complex, switching the enzyme from an oxidase to a hydroxylase in the presence of the substrate.
What are the official names of this protein?
Methane monooxygenase regulatory protein B.
What is the protein family that this protein belongs to?
Belongs to the TmoD/XamoD family.
Protein: CO3_CAVPO
Sequence: MGPAAGPSLLLLLLASVSLALGDPMYSIITPNILRLENEETVVLEAHEVQGDIPVTVTVHDFPAKKNVLSSEKTVLTSATGYLGTVTIKIPASKEFKSDKGRKLVVVQAAFGGTQLEKVVLVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVDSDLLPVGRTIIVTIETPDGIPIKRDTLSSNNQHGILPLSWNIPELVNMGQWKIQAFYENSPKQVFSAEFEVKEYVLPSFEVLVEPTEKFYYIDDPKGLEVNIIARFLYGKNVDGTAFVIFGVQDGDQRISLAQSLTRVVIEDGSGEVVLSRQVLLDGVQPSRPEALVGKSLYVSVTVILHSGSDMVEAERSGIPIVTSPYQIHFTKTPKYFKPAMPFEIMVLVTNPDGSPAPHVPVVTQGSNVQSLTQADGVARLSINTPNTRQPLSVTVQTKKGGIPDARQAINTMQALPYTTMYNSNNYLHLSMPRTELKPGETINVNFHLRSDPNQEAKIRYYTYLIMNKGKLLKVGRQPREPGQALVVLPMPITKELIPSFRLVAYYTLIGASAQREVVADSVWADVRDSCVGTLVVKGGSGKDGQDKRQQHLPRQQMTLRIEGNQGARVGLVAVDKGVFVLNKKHKLTQSKIWDVVEKADIGCTPGSGKDYAGVFTDAGLSFKSSKAGLQTAQREGLDCPKPAARRRRSVQLMERRMDKAGKYKSKELRRCCEDGMRENPMQFSCQRRARYVSLGEACVKAFLDCCTYMAQLRQQHRREQNLGLARSDMDEDIIPEEDIISRSQFPESWLWTIEELKEPERNGISTKTMNIFLKDSITTWEILAVSLSDKKGICVADPFEVTVMQDFFIDLRLPYSVVRNEQVEIRAVLYNYREAQSLKVRVELLHNPAFCSLATAKKRHTQTVTIGPKSSVAVPYVLVPLKIGLQEVEVKAAVYNYFISDGVKKTLKVVPEGMRVNKTVAIRTLNPEQLGQGGVQREEIPAADLSDQVPDTDSETKILLQGTPVAQMAEDAVDAERLKHLIITPSGCGEQNMIGMTPTVIAVHYLDQTEQWEKFGLEKRQEALNLINRGYTQQLAFKQPNWAYAAFKNRASSTWLTAYVVKVFSLAANLIGIDSEVLCGAVKWLILEKQKPDGVFQEDGPVIHQEMIGGVRTAQEADVSLTAFVLIALQEAKDICRAQVNNLEANINKAGDYIESRYADVRRPYTLAIAGYALALLERLNGATLQKFLNAATEKNRWEEARQKLYSVEATSYALLALLLLKDFDAVPPVVRWLNEQRYYGRGYGSTQATFMVFQALAQYQTDVPDHKDLNMEVALQLPSRSSPSKFRLVWEAGSLLRSEATKQNEGFKLTAKGKGQGTLSVVAVYYAKTKRKVVCKNFDLRVTLKPAPDTVKKPQEAKSTMILGICTRYLGDQDATMSILDISMMTGFIPDTDDLKLLATGVDRYISKYEMNKDFSKNTLIIYLDKVSHSEEECLSFKIHQFFNVGLIQPGSVKVYSYYNLDETCTQFYHPEKEDGMLNKLCHKDLCRCAEENCFIQLPEKITLDERLEKACEPGVDYVYKTKLLKMELSDDFDEYIMTIEQVIKSGSDEVQAGKERRFISHIKCRDALHLKEGKHYLMWGLSSDLWGERPNMSYIIGKDTWVEAWPEAEECQDEENQQQCQDLGTFTENMVVFGCPN
What is the function of this protein?
Acts as a chemoattractant for neutrophils in chronic inflammation.
What are the official names of this protein?
Complement C3.
What are the subcellular locations of this protein?
Secreted.
Protein: PSA1_ORYSJ
Sequence: MFRNQYDTDVTTWSPAGRLFQVEYAMEAVKQGSACVGLRSRTHAVLAAANKAASELSSHQRKVFRVADHAGVALAGLTADGRVLSRFLRSECINHAFVYDAPLPVSRLALRLADKAQVCTQRSWKRPYGVGLLVAGLDESGAHLYYNCPSGNYFEYQAFAIGSRSQAAKTFLERRFEGYNDYTPEQLIKDALSAIKETLQGEKLTSSNCTVAIVGRKDDGTVEPFEMIDVKRIQEIIDSMEAAEEAPAAEAESSSMQEEDKGTDAAPMDI
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-1, 20S proteasome alpha subunit F, 20S proteasome subunit alpha-6, Proteasome component C2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPA_DRIGR
Sequence: MVTLRVDEISNIIRERIEQYNREVTIVNTGTVLQVGDGIARIHGLDQVMAGELVEFEEGTVGIALNLESNNVGVVLMGDGLMIQEGSSVKATGRIAQIPVSEAYLGRVINALAKPIDGRGEISASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQKGQNVICLYVAIGQKASSVAQVVTTFQERGAMEYTIVVAETADSPATLQYLAPYTGAALAEYFMYRERHTSIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKSSSHLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSSDLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLELAQFAELEAFAQFASDLDKATQNQLARGQRLRELLKQSQSAPLTVEEQILTIYTGANGYLDPLDIGQVKKFLVQLRTHLKTNKPQFQEIISSTKTFTEQAEALLKEAIPEQMELFILQEQT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SECB_RUEST
Sequence: MAENGAAEGTAQQPQVQMNILGQFIRDLSFENVMAQKGVGGEVQPDVNVQVALDAKKRSTENQYEVITKLNIESKNKAGGEVLFVLELEYVGIFNIAGVPEDQLHPFLLIECPRMLFPFLRRIVSDISRDGGFPPLNLDNIDFVAIYRNELARRQAEAPAEVTN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XBP1_CAEEL
Sequence: MSNYPKRIYVLPARHVAAPQPQRMAPKRALPTEQVVAQLLGDDMGPSGPRKRERLNHLSQEEKMDRRKLKNRVAAQNARDKKKERSAKIEDVMRDLVEENRRLRAENERLRRQNKNLMNQQNESVMYMEENNENLMNSNDACIYQNVVYEEEVVGEVAPVVVVGGEDRRAFESAAFINEPQQWEQARSTSINNNISNQLRRMDSKKNNTISVDMYLTIISILCNHMDRNKKMDTSNKSSNISRAQAESSIDSLLATLRKEQTVMQRLVQADPCTHLQKRVKHFRRIP
What is the function of this protein?
Functions as a stress-inducible potent transcriptional activator during endoplasmic reticulum (ER) stress by inducing unfolded protein response (UPR) target genes via binding to the UPR element (UPRE) (By similarity).  Plays a role in modulation of the UPR, lipid metabolism, proteostasis, and lifespan (PubMed:23791175, PubMed:31303493, PubMed:31315038, PubMed:31570707).  In neurons, rescues stress resistance, increases longevity, and, drives expression of lysosomal genes in the intestine and activates the UPR in distal, non-neuronal cell types through a cell-nonautonomous mechanism (PubMed:23791175, PubMed:31303493, PubMed:31315038).  In neurons or intestine, plays a role in protection against proteotoxicity, acting via positive modulation of genes involved in lysosomal function, including lipases and the fatty-acid desaturase fat-6 (PubMed:31303493, PubMed:31315038).  Protection against proteotoxicity in neurons is dependent upon the transcription factor atf-6 (PubMed:31570707).
What are the official names of this protein?
X-box-binding protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLIGB_ELACL
Sequence: MKFLLFCCLFGTFLATGMCIDCEHCVVWGQNCTGWKETCGENEDTCVTYQTEVIRPPLSITFTAKTCGTSDTCHLDYVEANPHNELTLRAKRACCTGDECQTLPPPVLEPQVNRPNGLQCPGCIGLTSTECNEYLVSCQGSENQCLTIILKKPDFSLSEMSFKGCASENLCLLFEKKFWRFLEASEVDVKCTPAVPQTSQ
What is the function of this protein?
Inhibits the enzymatic activity of the phospholipase A2 (PLA2).
What are the official names of this protein?
Phospholipase A2 inhibitor gamma subunit B, PLI-gamma B, gamma-PLI B.
What is the protein family that this protein belongs to?
Belongs to the CNF-like-inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in blood plasma.
Protein: ACKA_STRPN
Sequence: MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTVKFDGRSEQQILDIENHIQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTVVEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRYPLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKAGKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLGVSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGENAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVERLKK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_OLEA2
Sequence: MEKSLQLEIVTPDKVVLSEQVDYVGAPGYEGEFGVLPNHIPFLSALSIGSLYYKAGGKTRYAFVSGGFAEVSDNKVTILAESAERAEDIDIERARKAQQRAEERLKAEREKIDATRAEAALKRALARLQVRNAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HDOX_LISMH
Sequence: MIIVTNTIKVEKGAAEHVIRQFTGANGDGHPTKDIAEVEGFLGFELWHSKPEDKDYEEVVVTSKWESEEAQRNWVKSDSFKKAHGRTKDTREQREDRKGIVGNAIARFEVVHVQNPVIVEK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme-degrading monooxygenase, Heme oxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATG1_CANLF
Sequence: MASQSQGIQQLLQAEKRAAEKVADARKRKARRLKQAKEEAQMEVELYRREREQEFQSKQQAAMGSQGNLSAEVEQATRRQVQGMQSSQQRNRERVLAQLLGMVCDVRPQVHPNYRIAV
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit G 1, V-ATPase subunit G 1, Vacuolar proton pump subunit G 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
What are the subcellular locations of this protein?
Apical cell membrane.
Protein: YFBU_SALTY
Sequence: MEMTNAQRLILSNQYKMMTMLDPTNAERYRRLQTIIERGYGLQMRELDREFGELTEETCRTIIDIMEMYHALHVSWTNLKDTQAIDERRVTFLGFDAATEARYLGYVRFMVNIEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: MURE_HAEI8
Sequence: MKKLTALFNLPELKNDIELHNMVLDSRKVKAGDLFVAIKGHQVDGNQFIDSALHSGASAVVSETELSSEHLTVAFIRNVPVVKYYQLARHLSSLADVFYDSPSKNLTLVGVTGTNGKTTISQLLAQWAELLGHRAAVMGTIGNGLLGQIVEAKNTTGSAVEIQSSLSTFKHAGADFTSIEVSSHGLAQHRVEALHFKAAIFTNLTRDHLDYHQSMENYAAAKKRLFTELDTQIKVINADDEIGYQWLTELPDAIAVSMNADFKVGSHQWMKAINIHYHFKGADITFESSWGNGVLHSPLIGAFNVSNLLLVMTTLLSFGYPLENLLATAKSLKGVCGRMEMIQYPNKPIVIVDYAHTPDALEKALIAAREHCQGELWCIFGCGGDRDRGKRPLMAQVAEQFAEKIIVTKDNPRTEPQSQIEADIVAGFKNMEKVGIIPDRAQAIQFAIESAVENDVILIAGKGHEHYQIIGSEVVHFSDQEIALDFLK
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_FRATM
Sequence: MSRRNRAPKRDILPDPKYKSQVVAKFVNHIMLSGKKSIAEKIVYGAFDKIKAKDASANEVEVFEKALESVSPMVEVKSRRVGGATYQVPVEVRPERRQTLGMRWIIDAARKRKENTMGDRVAAEILEAVEGRGAAVKKREDTHKMAEANKAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CX6A2_CANLF
Sequence: ASGAKGDHGGAGASTXXLLT
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.  Plays a role in the assembly and stabilization of complex IV (By similarity).
What are the official names of this protein?
Cytochrome c oxidase subunit 6A2, mitochondrial, Cytochrome c oxidase polypeptide VIa-heart, COXVIAH.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DHSC_RICPR
Sequence: MTKIKQEIYNKRPTSPHLTIYKPQISSTLSILHRMTGVALFFVVSILVWWLILSKYDNNYLQLASCCIIKICLVAFSYSWCYHLCNGIRHLFWDIGYGFSIKAVNITGWCVVVCSILLTMLLWV
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase cytochrome b556 subunit, Cytochrome b-556.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b560 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LTN1_DROME
Sequence: MGGKTKQAPRTKNNAKPSSSSRTAELLGSSTPIFVGFSAQTDGGGLVPFAPGFASAEQMPDSFDAAISPQTQIILRKLSKKDPMTKKKALQELHELIEQSDVEVLKNILPLWPKYYLNLASDPEHTVREQTQTVLQLLMAKCKKAMAPYLKLLVPVWLGSRFDTYAPAASIASQSFRDTFAGNANRSREVCMHCQVEILEYATRNLTFHTAATLSIGKSLTPEDAEQKYQRVIISSLKLLSFFMGQTAQTEELSQVKEGFGTLVAHQKFWSFAKHKVPAIKAAWFECIYHILQSVALLDVITPQKTQLTNLCFQFIDDADPVVAPHIWGCVLLLQSNYVDWFVPLNIRKTLLPKLSSLLQNGFNRNAQAICPNLLPFLSKVTQASLQDLDIYDFYQRFFDDMKLAVTKKFDPPLSKSDCIVIHNAYFECLRFLMQQINNNKQREQKEEEFSFSLLDNNVLEPIAWLLKSDSTHVKIFFQHSSALVAFWDRQINNRLDNGDLYAKLLNKFWIRIFELVTQDLSAEEVNEQLLGHVLLLVQDLHMANPSLESPSVKFVEGPNEKIEKSEPTTPVKKAQEAAAFIQKELKQLVIKLVRICLDKANKGSGSGTSSSRYIEQIRTLTKMFNDAAFYKSLTDDGDLASALNKFVSLLGQLSCQACESVVEIVFEILPLLETGKRFEYIENTLMKLPQHGVQNLLLHRLLSYPLCAEAAVRQMLSGPETCEMIARIAEEVVVDNDREKLNLLHKCFFQTDTGDILINAKTVDKILLSMCGPLEQPVVDDAVEVCGSFIAQIMPVICSNNNSSLHVRQHIFLKLFKFSLEHRPEDYLSEDTLWEITTCWQDGLSSKDIEIDDDMLKCCAGIVEELANSAELKADTLDGMAEAMAKFVICSTENIEDEYKRLERIDETLTALLETPLKTTDKVQQFENHCVLLEALHGSVTAGVPFENACLSRNEILPLLQRSTLNFSTIYKLVYQFPPPQDTNDPEDELTEDYCDPNADVLKKWNEPLIAELLQCIRVAGTAECWLEMSVLQSSTEELVLILSEKVQSFMGNSSDLVAIVKERLQQAAVQQSSVIDCRLLSYLRFCPQYAAFEESASILLHEDLSENLVTQGALKTYVIALQFLLPKLSQKAITLSSAIMGTEPPEIWVKAAVFHALLLNNFEGDVNEQTDRNIIVSAVQFMTSIGERQASQKDLLHYNVEIQRQPYESVINTVEFIKLLTEVLKRFPYELSIKNWDAIRIGLSSWVLSVSKSIAQYQDPKTSLFIVAVYELFAALIDFIRSEKQKSSTELLKNMIDEWDSLFAKEVNLVLFKSYYLLTHEVSVDPGFQACYEALLEQITPVIERLDYSFVYSFCKSNSNITLDHLCNFLFKQLYSVQHSVRLSAVHSLRQLTPHFVADDIELNEKQSESLDASTTICKWHFLNRFEDYLTRYDALITKYLEEFTFKLSELDDLEPIDRHNALSYLFLWDCIINACAKSPVALRAVYTNWLNDNKYEENFLHFLFRAMPVDILKNHGAKVHSNGVYKELTWSQQKDRHLPLERYACHLYTEVLRKLPAVVRRWWNATQSRQKNFIDNLTTNYVSSLICSEELKAIANRKEKHENMQVTVHSSTREVLAVYAIDEARMELVITLAPNYPLGAVKVECGKQIGGRASSRNVGMQLTIFLTHQNGTIYDGLTMWKNNLDKKFEGVEECYVCYTVIHQETCQLPKLTCKTCKKKFHGPCLYKWFTTSSKSTCPICRNVF
What is the function of this protein?
E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (PubMed:25128630).  Ubiquitination leads to TER94/VCP recruitment for extraction and degradation of the incomplete translation product (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase listerin, Listerin E3 ubiquitin protein ligase 1, RING-type E3 ubiquitin transferase listerin.
What is the protein family that this protein belongs to?
Belongs to the LTN1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: LRGA_BACAN
Sequence: MSTKKVYSFLSQAFIFSAIMLISNIIATHLPIPMPSSVIGLVILFSLLCLKVIKLEQVESLGTALTGIIGFLFVPSGISVINSLGVMGQYFVQILTVIVVATVILLAVTGLFAQFILGKDEKETEDTKELKVVNKGRKHGKVA
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA.  The LrgAB and CidA proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. LrgA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YGFZ_ESCF3
Sequence: MAFTPFPPRQPTASARLPLTLMTLDDWALATITGTDSEKYMQGQVTADVSQMTEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVRESQLTELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVIREGATTLLWFEHPAERFLIVTDEATANTLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDMNTLHIEPLPYSLEE
What is the function of this protein?
Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs.  It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication.
What are the official names of this protein?
tRNA-modifying protein YgfZ.
What is the protein family that this protein belongs to?
Belongs to the tRNA-modifying YgfZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y538_LIMRJ
Sequence: MSGHSKWHNIQGRKNAQDAKRGKIFQKISRDLYQAAKAGDPDPANNAQLRLVIDKAHAANMPKKNIDRAIAKASGIGGAKFEEVTYEGYGPGGVAVMVSALTDNKNRTASAVRSAFSHSGGSLGASGSVSYMFDRKGLIEILRDDLDKSEDDMLMDALDAGAEDMKATEEKFQIFTDPSSMTDVRDALQEQGYELDTAEVTMIPQNRTEVPADKAKQYRHLIDELTENDDVADIYETGILPDEDDDEE
What are the official names of this protein?
Probable transcriptional regulatory protein LAR_0538.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK5_EUBDI
Sequence: AGESSNEAKGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, EubDi-Capa-PK, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLME_CUPMC
Sequence: MAKNKFNQSWLHDHINDPYVKMAQREGYRARAAYKLKEIDDQDKLIQPGQVIVDLGAAPGSWSQYARNKLAASPRAKDGRIDGAVVAIDILPMEPVADVTFIQGDFREEEVFRQLEQVVLDASGGSRIDLVISDMAPNLSGVASADAARIEYLCDLALDFAQAHLKPEGSLLVKCFHGSGYSQIVEKFKRQFKVVASRKPKASRDKSSETFILGRYLKSVD
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.