PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_STRR6
Sequence: MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAVLAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLRAERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL29_PSEPW
Sequence: MMKANELREKSAQQLNEQLLGLLRDQFNLRMQKATGQLGQSHLLSQVKRDIARVKTVLNQQAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PRMA_ACTPJ
Sequence: MAWVQIRLNSTDKQAEQISDFLEEIGAVSVTFMDSQDTPIFEPLPGETRLWGNTDVVGLFDAETDMKAIVEALIASRLVEADFAHKIEQIEDKDWEREWMDNFHPMQFGKRLWICPSWREVPDSNAVNVMLDPGLAFGTGTHPTTALCLQWLDSLDLTGKTVIDFGCGSGILAIAALKLGAKQAIGIDIDPQAILASGNNAEANGVADRLQLFLAKDQPQDLQADVVVANILAGPLKELAPNIITLVKPQGDLGLSGILATQAESVCEAYAPDFNLDSVVEKEEWCRITGVKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SORAS
Sequence: QILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVIMPITSLFENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: G3P_ESCFE
Sequence: IVFRAAQKRSDIEIVAINDLLDADYMAYMLKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGIFLTDETARKHITAGAKKVVLTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAKVINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKVLPELNGKLTGMAFRVPTPNVSVVDLTVRLEKPATYEQIKAAVKAAAEGEMKGVLGYTEDDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLV
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GOT_CANSA
Sequence: MGLSLVCTFSFQTNYHTLLNPHNKNPKNSLLSYQHPKTPIIKSSYDNFPSKYCLTKNFHLLGLNSHNRISSQSRSIRAGSDQIEGSPHHESDNSIATKILNFGHTCWKLQRPYVVKGMISIACGLFGRELFNNRHLFSWGLMWKAFFALVPILSFNFFAAIMNQIYDVDIDRINKPDLPLVSGEMSIETAWILSIIVALTGLIVTIKLKSAPLFVFIYIFGIFAGFAYSVPPIRWKQYPFTNFLITISSHVGLAFTSYSATTSALGLPFVWRPAFSFIIAFMTVMGMTIAFAKDISDIEGDAKYGVSTVATKLGARNMTFVVSGVLLLNYLVSISIGIIWPQVFKSNIMILSHAILAFCLIFQTRELALANYASAPSRQFFEFIWLLYYAEYFVYVFI
What is the function of this protein?
Aromatic prenyltransferase involved in the biosynthesis of cannabinoids-related terpenophenolic natural products, which have pharmacological activity (PubMed:9607329, PubMed:30814733).  Catalyzes the transfer of geranyl diphosphate (GDP, GPP) to olivetolate to produce cannabigerolate (CBGA) (PubMed:9607329, PubMed:30814733).
What are the official names of this protein?
Geranylpyrophosphate:olivetolate geranyltransferase, chloroplastic, Prenyltransferase 4, CsPT4.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
Protein: EFPL_ECOLU
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: SYP_PICTO
Sequence: MENKKENFSEWYNEIIDLAKLSDKRYAIKGMNVWLPYGLKIMRLIDNIIRDNVDNKSFQEVSFPVLITRSQLETEFEHIKGFENEIYWVTKGGSEKLDIELALRPTSESAMYTMFPLWIRSHQDLPLKIYQIVSVYRYETKHTRSFIRVREIHFFEAHTAHVDYGDAERQMSEYMDIWSSIAEKLCLPYNIDMRPDWDKFPGAKYTLAFDTLMPSGRSLQIGTIHEYGENFARNYDIKYLDINGDLKYVSQTTFGLSERLLAAVIGIHGDDTGLILPASIAPVQAIIIPIPGKSFKEVLDYSGKILSMLKDINVRAEIDSRENYTPGYKYNDWEMRGVPLRIEIGSREMESSTVTVVSRLNKKRLNISIKEINNIKNMLNEHDKQLTLNAWKMMEENTVFIDDINNIPMNKDVLIKAYWCGSRECSDALEQKKDVTALGTLYNLNDSGKCIVCGNPGRLSMFARSY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSP9_CAEEL
Sequence: MSLTADPPACTVPAAGGSSTHKLVNGGAEKIIFKIKSSNNNEYRIAPVFGFVDPAGSKDVVITRTAGAPKEDKLVIHFAPAPADATDAQAAFAAVTPAGTVTIPMSATA
What are the official names of this protein?
Sperm-specific class P protein 9/11.
Protein: TSAD_ENT38
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATIGRSLAFAWDVPAIPVHHMEGHLLAPMLEENPPEFPFVALLVSGGHTQLISVTGIGEYELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKLASQGVEKRFVFPRPMTDRPGLDFSFSGLKTFAANTIRNNENDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFTRLVMAGGVSANRTLRTRLEEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRVKGGATADLSVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMERL_HUMAN
Sequence: MGKRRCVPPLEPKLAAGCCGVKKPKLSGSGTHSHGNQSTTVPGSSSGPLQNHQHVDSSSGRENVSDLTLGPGNSPITRMNPASGALSPLPRPNGTANTTKNLVVTAEMCCYCFDVLYCHLYGFPQPRLPRFTNDPYPLFVTWKTGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPLTREELPKLFCSVSLLTNFEDASDYLDWEVGVHGIRIEFINEKGVKRTATYLPEVAKEQDWDQIQTIDSLLRKGGFKAPITSEFRKTIKLTRYRSEKVTISYAEYIASRQHCFQNGTLHAPPLYNHYS
What are the official names of this protein?
AMMECR1-like protein.
Protein: MRAY_ECO5E
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GPA10_CAEEL
Sequence: MGVCQSFVLTDEMKDQIKVNKEIEKQLEKKKNMQLEQTVLLLGPGESGKSTVMKQMRAMTGNYTKTELHERKVLIIQNLCQFSEMLLEYVREYILEMTEDDDKRYTVMCEELKMAVIHDGIMRPELADTLKEFWGNSAIQDAYSKRDTFHLTDSAKYFFDNIDRIKLPGFEPTNQDIVHIRVPTTGVAQVEVIMNNIKLMICDCGGQRSERRKWYHFFDEADAVLFVAAISEFDQKLAEDEETNRMHESIRLFWTVFNGKFFKKAAVILFLNKIDLFEEKVKHVKIKDYFPKFEGANTVSEGTKFFRRQFREGIHPDFKKRMYTHETCAISDQVQIIINTVIDTVIQDNLKDTGMI
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-10 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: EAA4_CANLF
Sequence: MSSHGNSLFLRESGQRLGRVGWLQRLQESLQQRALRTRLRLQTMTREHVLRFLRRNAFILLTVSAVVIGVSLAFALRPYQLTYRQIKYFSFPGELLMRMLQMLVLPLIVSSLVTGMASLDNKATGRMGMRAAVYYMVTTVIAVFIGILMVTIIHPGKGSKEGLHREGRIETIPTADAFMDLVRNMFPPNLVEACFKQFKTQYSTRLVTRTIVRTENGSELGTSMPPPSSMDNGTSLLENVTWALGTLQEVLSFEETVPVPGSANGINALGLVVFSVAFGLVIGGVKHKGRVLRDFFDSLNEAIMRMVGIIIWYAPVGILFLIAGKILEMEDMAVLGGQLGMYTLTVIVGLFLHAGGVLPLIYFLITHRNPFPFIGGVLQALITAMGTSSSSATLPITFRCLEEGLGVDRRITRFVLPVGATVNMDGTALYEALAAIFIAQVNNYELNLGQITTISITATAASVGAAGIPQAGLVTMVIVLTSVGLPTEDITLIIAVDWFLDRLRTMTNVLGDSIGAAVIEHLSQRELELQEAELTLPSLGKPYKPLMAQEKGASRGRGGNESAM
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate.  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion.  Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport.  Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate.
What are the official names of this protein?
Excitatory amino acid transporter 4, Sodium-dependent glutamate/aspartate transporter, Solute carrier family 1 member 6.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. SLC1A6 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPF_HAES1
Sequence: MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLVAHSDGDVALHALTDALLGAMALGDIGKLFPDTDIQYKGADSRRLLRTAYQAILDKGYQVGNVDITIIAQAPKMRPYIDAMRTVIAQDLHCDIEQVNVKATTTEKLGFTGRSEGIACEAVALLIKQTGTK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: AROE_BORPD
Sequence: MSQASPLPRYAVIGNPVAHSRSPQIHAMFSSQTGKPLQYERLLAPVDGFAATVQAFREQGGLGLNVTVPFKEEACQLAGAHLSERARLAGAVNTLWLRDGAWHGCNTDGVGLVSDLLRLGVVLEGARVLLVGAGGAARGVLQPLAAAGCARIHIVNRSAQRAHDLAAGWAAAGAVPGTRVTAGALAEAGVAGGWNVVVNATASSLQGAAPELPRGLYAPDALAYDMMYAAHPTAFMRQATDDGAARTADGLGMLVGQAAESFLIWHGVRPDPSPVLTALRATLLAKD
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CRGC_BOVIN
Sequence: MGKITFYEDRGFQGRCYQCSSDCPNLQPYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGDYPDYQQWMGFNDSIRSCCLISDTSSHRLRLYEREDQKGLIAELSEDCPCIQDRFRLSEVRSLHVLEGCWVLYEMPNYRGRQYLLRPQEYRRYQDWGAVDAKAGSLRRVVDLY
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin C, Gamma-C-crystallin, Gamma-crystallin IIIA.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: YIDC_AGRFC
Sequence: MEKNRNYFIAIALSVVIVLAWQFLYMNPRIEQQRRAEEARQAQQQTTQQQPAPGAAPGATVEGAPPASSTQAAATATREEAIARTQRVAIDTNAIAGSINLTGARFDDIRLKGYHETVDDSSPIITLFSPADTKDGYFTELGYVAAQEVGGVPGPTTVWTLASGDKLTETTPVTLTYTNSKGVVFSRTVSIDEHYMLSIADKVENPGQAAISFATYGRVTRNNKPVIPPVFVIHEGFLGVSGKDGSLTEKKYKDVEEEPVTVAKATGGWLGITDKYWAAAIVPPQTTPFETRYSHITGNQPSYQADFKSDSMTVEAGQSIELKSLVFAGAKEVPLVDRYETEYSVPKFDLLIDWGWFYFITKPMFKMMDFFFRYFGNFGVAILLTTIVVKALFFPLASKQYASMANMKRMQPKMEELKAKHGDDRMAMQQAMMQLYKEEKINPVAGCWPMLLQIPVFFALYKVIYVTIEMRHAPFFGWIHDLSAPDPTSLFNLFGLLPYDVPHFLMIGVWPLVMGITMFLQMRMNPTPPDPTQAMIFTWMPLIFTFMLASFPAGLVIYWAWNNTLSISQQALIMKRHGAKIELFDNIKGLFKRKPVQSK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GDIB_MOUSE
Sequence: MNEEYDVIVLGTGLTECILSGIMSVNGKKVLHMDQNPYYGGESASITPLEDLYKRFKLPGQPPASMGRGRDWNVDLIPKFLMANGQLVKMLLFTEVTRYMDFKVIEGSFVYKGGKIYKVPSTEAEALASSLMGLFEKRRFRKFLVYVANFDEKDPRTFEGVDPKKTSMRDVYKKFDLGQDVIDFTGHSLALYRTDDYLDQPCCETINRIKLYSESLARYGKSPYLYPLYGLGELPQGFARLSAIYGGTYMLNKPIEEIIVQNGKVVGVKSEGEIARCKQLICDPSYVKDRVEKVGQVIRVICILSHPIKNTNDANSCQIIIPQNQVNRKSDIYVCMISFAHNVAAQGKYIAIVSTTVETKEPEKEIRPALELLEPIEQKFVSISDLFVPKDLGTDSQIFISRAYDATTHFETTCDDIKDIYKRMTGSEFDFEEMKRKKNDIYGED
What is the function of this protein?
GDP-dissociation inhibitor preventing the GDP to GTP exchange of most Rab proteins.  By keeping these small GTPases in their inactive GDP-bound form regulates intracellular membrane trafficking.  Negatively regulates protein transport to the cilium and ciliogenesis through the inhibition of RAB8A.
What are the official names of this protein?
Rab GDP dissociation inhibitor beta, Rab GDI beta, GDI-3, Guanosine diphosphate dissociation inhibitor 2, GDI-2.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: TM204_BOVIN
Sequence: MTVRKVVATAVLVALVSLVLNNAAAFTPNWVYQTLEDGRRRSVGLWWACWLVERPRGAPGPGARPGPADVRDCEALGWGSEAAGFQESRGTVKLQFDMMRACNLVATAALAAGQLTFVLGLTGLPLLSPDAQCWEEAMAAAFQLASFVLVIGLVTFYRIGPYTSLSWSCYLNIGACLLATLAAAMLIWNVLHRREDCTAPRVIVISRSLTARFRRGLDNDYVESPC
What is the function of this protein?
Can influence paracellular permeability.  Appears to be involved in cell-cell interactions through adherens (By similarity).
What are the official names of this protein?
Transmembrane protein 204, Claudin-like protein 24.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell membrane; Multi-pass membrane protein. Note=Co- localizes with the beta-catenin adherins.
Protein: PRDX6_PIG
Sequence: MPGGLLLGDEAPNFEANTTIGRIRFHDFLGDSWGILFSHPRDFTPVCTTELGRAAKLAPEFAKRNVKMIALSIDSVEDHLAWSKDINAYNGEEPKETLPFPIIDDKSRDLAIQLGMLDPAEKDEQGMPVTARVVFIFGPDKKLKLSILYPATTGRNFDEILRVIISLQLTAEKRVATPVDWKNGDSVMVLPNIPEEEAKKLFPKGVFTKELPSGKKYLRYTPQP
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively (By similarity).  Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides (By similarity).  Also has phospholipase activity, and can therefore either reduce the oxidized sn-2 fatty acyl group of phospholipids (peroxidase activity) or hydrolyze the sn-2 ester bond of phospholipids (phospholipase activity) (By similarity).  These activities are dependent on binding to phospholipids at acidic pH and to oxidized phospholipds at cytosolic pH (By similarity).  Plays a role in cell protection against oxidative stress by detoxifying peroxides and in phospholipid homeostasis (By similarity).  Exhibits acyl-CoA-dependent lysophospholipid acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (By similarity).  Shows a clear preference for LPC as the lysophospholipid and for palmitoyl CoA as the fatty acyl substrate (By similarity).
What are the official names of this protein?
Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, Acidic calcium-independent phospholipase A2, aiPLA2, Glutathione-dependent peroxiredoxin, Lysophosphatidylcholine acyltransferase 5, LPC acyltransferase 5, LPCAT-5, Lyso-PC acyltransferase 5, Non-selenium glutathione peroxidase, NSGPx.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Lysosome. Note=Also found in lung secretory organelles (lamellar bodies).
Protein: CT13_CONCL
Sequence: MRCLPVFIILLLLASTAAVDVAGSKLKRRLERKPYQGSQAYVKKTAFGLRKCCKRHHGCHPCGRK
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal1.3, Conotoxin Cal1.1a, Conotoxin Cl1.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMK_THISH
Sequence: MKIAILSRDAKLYSTRRLMEAARANGHEVQVLDPLRCYMNITSAKPTIHYKGKELTGFDAVIPRIGASITFYGTAVLRQFEMMGVFPVNESVAISRARDKLRSLQLLSRKGVGLPVTGFAHSPDDIDDLLAEVQGAPLVVKLLEGTQGVGVVLAETRKAAESVIQAFMGLRQNILVQEFVKEAGGTDLRCFVIGGKVVAAMQRRAKEGEFRSNLHRGGSAEPVKLTPQERATAVKAAKVIGLNVCGVDILRSSHGPVVIEVNASPGLEGIETASGVDVAGRIVSFIEQNARPHRTQTRGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: IAGB_SALTS
Sequence: MHYFFIIVIWLLSINTAWADCWLQAEKMFNIESELLYAIAQQESAMKPGAIGHNRDGSTDLGLMQINSFHMKRLKKMGISEKQLLQDPCISVIVGASILSDMMKIYGYSWEAVGAYNAGTSPKRSDIRKRYAKKIWENYRKLKGMSAEEKNKRLSIAANK
What are the official names of this protein?
Invasion protein IagB.
What is the protein family that this protein belongs to?
Belongs to the IagB/IpgF/P19 family.
Protein: NIG2A_ODOHO
Sequence: GLLGSLFGAGKKVACALSGLC
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacterium S. aureus ATCC 25923 (MIC=56 uM) and the Gram-negative bacterium E. coli ATCC 25726 (MIC=28 uM).
What are the official names of this protein?
Nigrocin-2HSa.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ICAM1_RAT
Sequence: MASTRARPMLPLLLVLVAVVIPGPVGAQVSIHPTEAFLPRGGSVQVNCSSSCEDENLGLGLETNWMKDELSSGHNWKLFKLSDIGEDSRPLCFENCGTTQSSASATITVYSFPERVELDPLPAWQQVGKNLILRCLVEGGAPRTQLSVVLLRGNETLSRQAVDGDPKEITFTVLASRGDHGANFSCFTELDLRPQGLSLFKNVSEVRQLRTFDLPTRVLKLDTPDLLEVGTQQKFLCSLEGLFPASEAQIYLEMGGQMLTLESTNSRDFVSATASVEVTEKLDRTLQLRCVLELADQTLEMEKTLRIYNFSAPILTLSQPEVSEGDQVTVKCEAHGGAQVVLLNSTSPRPPTSQGTSPRPPTSQIQFTLNASPEDHKRRFFCSAALEVDGKSLFKNQTLELHVLYGPHLDKKDCLGNWTWQEGSQQTLTCQPQGNPAPNLTCSRKADGVPLPIGMVKSVKREMNGTYKCRAFSSRGSITRDVHLTVLYHDQNTWVIIVGVLVLIIAGFVIVASIYTYYRQRKIRIYKLQKAQEEALKLKVQAPPP
What is the function of this protein?
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2).  During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By similarity).
What are the official names of this protein?
Intercellular adhesion molecule 1, ICAM-1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. ICAM family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RBFA_CHLPN
Sequence: MTENRRIKRVNALLQEAIAKVILKDVKHPKISNLWITVTRVSLSKDLHSARVYVSVMPHENTKEEALEALKVSAGFIAHRASKNVVLKYFPELHFYLDDIFSPQDYIENLLWQIQEKEKS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_HYPNA
Sequence: MTQPISSALVLFSGGQDSATCLAWALDRFDRVETIGFDYGQRHAIELACRPKVRAAIRQMSPVWAEKLGEDHMIDAGVLKSLGATAMTHEVEISMTAAGLPNTFVPGRNLLFFTLAGALAVRRGIGVLVGGMCETDYSGYPDCRADTLKAQEQTLRLGLDADIRIDAPLMYLDKAATWQLAQELGGDALVALIGEETHTCYLGERGARHDWGYGCGTCPACELRSNGWQRWQDGKAAAP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MOAC_BACP2
Sequence: MSQFSHFNEQGRAKMVDISDKSSTMRTAVAASSVRMIKEVFHKIEQREIGKGDVLSVAQVAGIMAAKQTSTIIPMCHPLALKGVDISFDWEEDGNAHILNIQVQVKTKGSTGVEMEALTSASVCALTVYDMCKAIDKGMIIGPTYLIEKTGGKNGDFHRASDI
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RL31_NEIMA
Sequence: MKQGIHPNYHEVNVTCSCGNKFATKSAMEKENFNIEVCSLCHPFYTGTQKIVDTTGRVDKFNNKFGNLFKR
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.