PharMolix/UniProtQA huggingface dataset:
Protein: ARGD2_BRADU
Sequence: MTTATHPYDALMDITARPKAVFVRGAGSYLWDDSRKRYLDFVQGWAVNCLGHSPSAIADALAAQAKRLLTPSPAFYNEPSLKLAQALVANSAFDQVFFANSGAEANEGAIKLARKYGSLHKGGAFEIISFEGGFHGRTLATMSASGKKAFEPLFEPKVAGFKKAKLNDIASVEKLINDNTVAVMLEPIQGESGVWPATDQFLQELRALTKAHGLLLILDEIQTGMGRTGKLFHYEHTGIAPDIMTLGKGIGGGVPLAALLATERAACFEHGDQGGTFNGNPIMCAAGLAVLDEVGKPDFLKSVTETGLLLESELQKVSARHGLGGVRGRGLLLALDLKLPIAPGIVAQAFEAGVLLNAPQVDTLRFMPALNVTRAEIAEMIDCLDAILTKAGAARRVA
What are the official names of this protein?
Acetylornithine aminotransferase 2, ACOAT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_HELPH
Sequence: MRHYETMFILKPTLVEEEIKSKIEFYKEVITKHHGVIETSLDMGMRNLAYEIKKHKRGYYYVAYFKAEPSMILELERLYRINEDVLRFIVIKYESKKEVEAWHALVDRANKKPSHAKEKHEKTEHTHSHHLEEAESVGSHSE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: UPP_CAMJ8
Sequence: MKNIHCINHPLIEHKLGILRAKETKPFQFRMLIDEISSFLLFEASKDFSLKEIEISTPIQKTTVKKLDEKIMICPILRAALGMLESVFKMIPDASVGFLGFVRNEETLKADFYFQKLPKDAKKRTAIVIDPMFATGGTAIEACNFLKSQGVKKIKFISILAAPQGLKKFSQMHDDVEVFVACIDEGLNEKGYIIPGLGDAGDRVFNTL
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NRG1_XENLA
Sequence: MAEKKKVKEGKGRKGKGKKDRKGKKAEGSDQGAAASPKLKEIKTQSVQEGKKLVLKCQAVSEQPSLKFRWFKGEKEIGAKNKPDSKPEHIKIRGKKKSSELQISKASSADNGEYKCMVSNQLGNDTVTVNVTIVPKPTYNHLLLMKIYLKVTSVEKSVEPSTLNLLESQKEVIFATTKRGDTTAGPGHLIKCSDKEKTYCVNGGECYVLNGITSSNQFMCKCKPGFTGARCTETDPLRVVRSEKHLGIEFMEAEELYQKRVLTITGICIDLLVVGDMCVVDAYCKTKKQRKKLNDRLRQSLRERNKNITNKDNRPHNPKNPPPRKNVQLVNQYVSKNVISSEHVIERETETSFSTSHYTSTTHHSTTVTQTPSHSWSNGLSESMISEKSYSVIVTSSVENSRHTSPTGPRGRLNGIGGPRDCSYLRHARDTPDSYRDSPHSERYVSAMTTPARMSPVEFKTPISPKSPCLETSPPESSLAVSVPSVAVSPFIEEERPLLLVSPPRLREKRYDRKTPQKTPHKQHNSYHHNPGHDSSSLPPNPLRIVEDEEYETTQEYEPSLEPAKKLVNSRRQKRTKPNGHISNRLELDSDSSSESSTSESETEDERIGEETPFLSIQNPLAASLESASLYRHADSRTNPTSRFSTQEELQARLSSIANQALCDQKKRKMTCKTLFI
What is the function of this protein?
Direct ligand for the ERBB tyrosine kinase receptors.  Induces expression of acetylcholine receptor in synaptic nuclei.
What are the official names of this protein?
Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1.
What is the protein family that this protein belongs to?
Belongs to the neuregulin family.
What are the subcellular locations of this protein?
[Pro-neuregulin-1, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein. Note=Does not seem to be active. SUBCELLULAR LOCATION: [Neuregulin-1]: Secreted.
Protein: MUTS2_CALS4
Sequence: MKGMREKTLKSLEFDKIVKLIANECDSELGREKVFDIEIKKDLKAIEFELDLLNEAVKFIYSYGDISFSFQDIREHVKKAQIDYILYNRELLGIKNFLSLVEEVKAHFKSLYDREDFLLLKEFDKRLVPLKSLKEKIENTVISEDEISDEASPVLKAIRRQKASINEKIKSTLNSIISTRQKELQEPIITMRQGRYVVPVKQEYRNVFKGIIHDQSSTGATLFIEPIQVVDLNNELRELELKEQKEIERILFELSQEVKKNAEAIFKDVEVVSELDFLFAKARYSIKIKASRPELNTSGYVNLKKARHPLIDPEKVVPIDIHIGREFTTLVITGPNTGGKTVTLKTVGLLTLMAMAGINIPAEEKSQISIFEDVFVDIGDEQSIEQSLSTFSSHMTNIVSILKKVNKNSLVLLDELGAGTDPLEGSALAMSILDFLHRTGCRTIATTHYSELKQYALKTKGVENASVEFDVETLRPTYRLIIGIPGRSNAFEISRRLGLSEEIIENAKSYMSGEAIRFEDVIKDVEEKRKDLENAYQEVERLKKEVEVLKEELEKEKRKLESQKDKILKEAKEKAREIIKEAKQTAEEVIKRIKEAEEKEKNKDRAIQEIREKIKKNLEELEEEVLKPKEFSYGKIPDSLKAGQTVYIVPLDQNGIVLSPPDASGNVEVQAGILKMTVHISNLRVKEEQEQEEVKKGYSRFINEKAKSISPSLDVRGMTLDDALLEVEKYIDDAYLAGLNQVTIIHGRGTGVLRTGIAKFLRNSKYVKSFRLGRYGEGGDGVTIVELHSR
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: LRMDA_HUMAN
Sequence: MEKYLSLSGNHSSNKRSLEGLSAFRSLEELILDNNQLGDDLVLPGLPRLHTLTLNKNRITDLENLLDHLAEVTPALEYLSLLGNVACPNELVSLEKDEEDYKRYRCFVLYKLPNLKFLDAQKVTRQEREEALVRGVFMKVVKPKASSEDVASSPERHYTPLPSASRELTSHQGVLGKCRYVYYGKNSEGNRFIRDDQL
What is the function of this protein?
Required for melanocyte differentiation.
What are the official names of this protein?
Leucine-rich melanocyte differentiation-associated protein.
Protein: RS11_BRUO2
Sequence: MAKEATRVRRRERKNISSGVAHVNSTFNNTMITITDAQGNAIAWSSAGAQGFKGSRKSTPFAAQIAAEDCAKKAQEHGMRSLEVEVCGPGSGRESALRALQAAGFVITSIRDVTPIPHNGCRPRKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL131_ARATH
Sequence: MKHNNVIPNGHFKKHWQNYVKTWFNQPARKTRRRIARQKKAVKIFPRPTSGPLRPVVHGQTLKYNMKVRTGKGFTLEELKAAGIPKKLAPTIGIAVDHRRKNRSLEGLQTNVQRLKTYKTKLVIFPRRARKVKAGDSTPEELANATQVQGDYLPIVREKPTMELVKLTSEMKSFKAFDKIRLERTNKRHAGARAKRAAEAEKEEKK
What are the official names of this protein?
60S ribosomal protein L13-1, Protein BBC1 homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPTA_BORJA
Sequence: MGKILFFGLLLICIFLGFFFYKQKENNIIYNRIVEKFEDNVVIDEIYTHLFKDSNLKELVFIKSQLIIPELEHKKMIKATGYRADAYKALSTVYRFDFKVHDNKILGFKSVIFEGFEDAKVSKHENNLPSEKWQQLKDFNIGDPNINEKFFHLEFPFVVKNTLCVTISKGFFKKIKKLKRLKIMLISNEDREYKIDIENFLPKYNL
What is the function of this protein?
Virulence-associated protein essential for survival of the bacterium within the tick host and therefore within the natural life cycle of the spirochete.
What are the official names of this protein?
Protein BptA, Borrelial persistence in ticks protein A.
What is the protein family that this protein belongs to?
Belongs to the BptA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PAND_BURO1
Sequence: MQRHMLKSKIHRAAVTHCELHYEGSCAIDEDLLEAAGLIENERIDIWNINNGERFSTYAIKGERGSGMISLNGSAARRAQLGDLVIIAAFAMVDEAELQAGWKPKLVFIDDGNKIKGHRDHVPTQNWT
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
Protein: NPCL1_RAT
Sequence: MAAAWLGWLLWALLLSAAQGELYTPKHEAGVCTFYEECGKNPELSGGLTSLSNVSCLSNTPARHVTGEHLALLQRICPRLYNGPNTTFACCSTKQLLSLESSMSITKALLTRCPACSDNFVSLHCHNTCSPDQSLFINVTRVVERGAGEPPAVVAYEAFYQRSFAEKAYESCSQVRIPAAASLAVGSMCGVYGSALCNAQRWLNFQGDTGNGLAPLDITFHLLEPGQALPDGIQPLNGKIAPCNESQGDDSAVCSCQDCAASCPVIPPPEALRPSFYMGRMPGWLALIIIFTAVFVLLSAVLVRLRVVSNRNKNKAEGPQEAPKLPHKHKLSPHTILGRFFQNWGTRVASWPLTVLALSFIVVIALAAGLTFIELTTDPVELWSAPKSQARKEKSFHDEHFGPFFRTNQIFVTARNRSSYKYDSLLLGSKNFSGILSLDFLLELLELQERLRHLQVWSPEAERNISLQDICYAPLNPYNTSLSDCCVNSLLQYFQNNRTLLMLTANQTLNGQTSLVDWKDHFLYCANAPLTFKDGTSLALSCMADYGAPVFPFLAVGGYQGTDYSEAEALIITFSLNNYPADDPRMAQAKLWEEAFLKEMESFQRNTSDKFQVAFSAERSLEDEINRTTIQDLPVFAVSYIIVFLYISLALGSYSRCSRVAVESKATLGLGGVIVVLGAVLAAMGFYSYLGVPSSLVIIQVVPFLVLAVGADNIFIFVLEYQRLPRMPGEQREAHIGRTLGSVAPSMLLCSLSEAICFFLGALTPMPAVRTFALTSGLAIILDFLLQMTAFVALLSLDSKRQEASRPDVLCCFSTRKLPPPKEKEGLLLRFFRKIYAPFLLHRFIRPVVMLLFLTLFGANLYLMCNINVGLDQELALPKDSYLIDYFLFLNRYLEVGPPVYFVTTSGFNFSSEAGMNATCSSAGCKSFSLTQKIQYASEFPDQSYVAIAASSWVDDFIDWLTPSSSCCRLYIRGPHKDEFCPSTDTSFNCLKNCMNRTLGPVRPTAEQFHKYLPWFLNDPPNIRCPKGGLAAYRTSVNLSSDGQVIASQFMAYHKPLRNSQDFTEALRASRLLAANITADLRKVPGTDPNFEVFPYTISNVFYQQYLTVLPEGIFTLALCFVPTFVVCYLLLGLDMCSGILNLLSIIMILVDTIGLMAVWGISYNAVSLINLVTAVGMSVEFVSHITRSFAVSTKPTRLERAKDATVFMGSAVFAGVAMTNFPGILILGFAQAQLIQIFFFRLNLLITLLGLLHGLVFLPVVLSYLGPDVNQALVQEEKLASEAAVAPEPSCPQYPSPADADANVNYGFAPELAHGANAARSSLPKSDQKF
What is the function of this protein?
Plays a major role in cholesterol homeostasis (PubMed:17135346).  Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte (PubMed:17135346).  Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol (PubMed:17135346).  Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia (PubMed:15928087).  May have a function in the transport of multiple lipids and their homeostasis, thereby influencing lipid metabolism regulation (By similarity).  May be involved in caveolin trafficking from the plasma membrane (By similarity).  Acts as a negative regulator of NPC2 and down-regulates its expression and secretion by inhibiting its maturation and accelerating its degradation (By similarity).
What are the official names of this protein?
NPC1-like intracellular cholesterol transporter 1, Npc1l1, Niemann-Pick C1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the patched family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Subfractionation of brush border membranes from proximal enterocytes suggests considerable association with the apical membrane fraction. Exists as a predominantly cell surface membrane expressed protein.
Protein: SSRP_BURP0
Sequence: MSIIDNRKAFFDYHIEERYEAGLVLEGWEVKALRAGRGQIKEGYVVVKHAEIFLIGTHISPLPEASTHIKPDPVRTRKLLLHRDEIKKLIGKVEQRGYTLVPLNFHYKGGRVKCEIGLAKGKKLHDKRETEKKRDWEREKARIMRSAT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MTNN_BACHK
Sequence: MRIAVIGAMEEEVRILRDKLEQAETETVAGCEFTKGQLAGHEVILLKSGIGKVNAAMSTTILLEKYKPEKVINTGSAGGFHHSLNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADEALVALAEKCMQAEENIQVVKGMIATGDSFMSDPNRVAAIRDKFENLYAVEMEAAAVAQVCHQYEVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLEELK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: RLMD_XANC8
Sequence: MARSRNRFDRTPFQTAITDLSHDGRGVARRDGEGGKVTFISGALPGEVVVAEPTARSRHFDEAKTVEVLQASPQRVAPRCPHFGVCAGCVLQHLEESQQIVAKQRVLMDNLERIGHVTPQTVLPALVGDTWGYRRKGRFSVRRVEKKDKTLVGFRELDPRFVADLSVCYTVIPQIGEKIPQLAALVEGMDGKRDIPQIEFIAGDDAVALTIRHLQPLSARDEQALVEFAQAHDFAIFLQPGGVDSVHPLWPQEVPLSFRLPKWDVELAFRPLDFIQVNASLNQKMIAHALALLDAKPDDRVLDLFCGLGNFTLPLARTVREVVGVEGDAGLVARARENAQRNGLDNAQFYAADLTQDQRQTAWMRQGFDKLLLDPPRSGAIDVLQQLPLKQFKRIVYVSCHPGSLARDAGYLVNEQGFSLLSAGAMDMFPHTAHVESIAVFEKR
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: Y588_STRGC
Sequence: MVSVLVVGYKAFDLGIFGDKDQRLKIIKAAIRRDLIYLLENGMKWLVFTGNLGFEVWVLEVAKELQEEYNFQLATIFIFENQGENWNEANQEKLANFKNVDFIKYAYPSYENPSQFRTYNQFLLESTDGAYLFYDEENETKLKYLYRMMKENKQYHIKKLTFDDLNEMAENFSEI
What are the official names of this protein?
UPF0398 protein SGO_0588.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: Y2026_YERPA
Sequence: MNLQQQLAYCQQHQQRLQLRHFDNETAWQLGEKIKRQAEKQGVALAIDITVNHQTLFSYAMAGTCAENQDWLRRKRNVVELLSTSSYAAGLMLQQRETSLDARYGVSLRDYAALGGAFPLQIKQAGIIGSVNVSGAPHLDDHNLLLQVLADFVGLPTGSIELLTPLTPLSA
What are the official names of this protein?
UPF0303 protein YPA_2026.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: RS4_PARP8
Sequence: MARYIGPKAKLSRREGTDLFLKSARRSLADKCKLDSKPGQHGRTSGARTSDYGTQLREKQKVKRIYGVLERQFRRYFAEADRRKGNTGENLLKLLESRLDNVVYRMGFGSTRAEARQLVSHKAITVNGVVANIPSLQVKAGDVIAVREQAKKQARILEALSLAEQGGLPQWVAVDSKKFEGTFKSMPERSDIAGDINESLIVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS19_MACCJ
Sequence: MARSLKKGPFIDDHLMKKVEALEEGGKKTVIKTWSRRSTIFPNFIGHTIAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTYKGHGADDKKTKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: V031_FOWPN
Sequence: MPFLIELLRITGIVTLCPKYRLDRNSLLLVATKRNYIDVVRYLVKKGVDINFQETIRDNLTPLMIASRFNSHQLVELLLNNGAIINQRSLTCGNTALHLAVKNDNRITVDILLFHGANTNITNNDGFTPLHKAVIYNASIDIIKKLLRYKADVNIRDNEEENTGLTPLDIAMSCNNYEIISLLVSHVIRLDYSTCMSNKTKGFDHNKKLVKDNKRLQRIAIHCLKDIEKMKQVSINSRFTLFDLFVNNNVDLLLRCINKDNRFIVNFDKKLTVFNILYTDFIDTFMSRHVLLNKASKVLEDLFLDNDSNTSSWNNLPNEIKDHIFTYINNDELKIMTGSKT
What are the official names of this protein?
Putative ankyrin repeat protein FPV031.
Protein: RL32_BORRA
Sequence: MAVPKFKPSKSRSRTRRSINMRKKIPQFQECSNCGNLAIRHRICAKCGYYRNSQYLELGL
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GLYA_ACTSZ
Sequence: MLEKKTIAELDPVLWDAMQNEVRRQEEHIELIASENYVTPAVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGAEYANVQPHSGSQANAAVYGALLSAGDTILGMDLAHGGHLTHGAKVSFSGKIYNSVLYGITADGVIDYADVRTKALESKPKMIVAGFSAYSQVIDWAKMREIADEVDAYLFVDMAHVAGLIAAGLYPNPLPHAHVVTTTTHKTLAGPRGGLILSACGDEDIYKKLNSSVFPANQGGPLMHVIAAKAVCFKEALEPSFKVYQAQVLKNAKAMVEVFKQRGFDVVSNGTENHLFLVSFIKQGLTGKQADAALGAANITVNKNSVPNDPQKPFVTSGIRVGSPSITRRGFSETDAATLAGWMCDVLESIGKDNHEQVIAETKTKVLDICKRLPVYGIGR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPBP_MOUSE
Sequence: MLLLLTLAFLASPTCRAQNVLGNAAGKYFYVQGEDQGQLKGMRIFLSVFKFIKGFQLQFGSNWTDVYGTRSDNFIDFLLEDGEHVIKVEGSAVICLTSLTFTTNKGRVATFGVRRGRYFSDTGGSDKHLVTVNGMHAPGLCVRGIGFKWGNINANGNDHYNNKEDKADNKDADNKDADNKDDGDEDDDGNDDDDQKDES
What is the function of this protein?
This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding.
What are the official names of this protein?
Prostatic spermine-binding protein, SBP, Major prostatic secretory glycoprotein, P25.
What is the protein family that this protein belongs to?
To rat SBP.
Protein: ITIH3_MESAU
Sequence: MWWPYLVLALLSGLEASGFPRSPLRLLGKRSLPEGVVDGVEVYSTKISCKVTSRFAHNVVTTRAVNRADQAKEVSFDVELPKTAFITNFTLTIDGVTYPGNIKEKEVAQKQYDKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVRHFEIDAHIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTIVYDVNRESPGNVQVVNGYFVHFFAPQGLPVVPKNIVFVIDISGSMAGRKIQQTRVALLKILDDMKQDDYLNFILFSTGVTTWKDSLVQATPANLEEARTFVRSISDQGMTNINDGLLRGIRMLTDAREQHTVPERSTSIIIMLTDGDANTGESRPEKIQENVRKAIEGRFPLYNLGFGNNLNYNFLETMALENHGVARRIYEDSDANLQLQGFYEEVANPLLTNVEVEYPENAILDLTKNSYPHFYDGSETAVAGRLADSDMNNFKADVKGHGALNDLTFTEEVDMKEMDAALKEQGYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTAQALELSLKYHFVTPLTPMVVTKPEDNEDQTSIADKPGEDAPYAATSTAYLTSHQSPPTPYYYVDGDPHFIIQVPGKNDTICFNIDEKPGTVLRLIQDPVTGITVTGQIIGDKGSSPYSRTGKTYFGKLGITHAWMDFRIEVTTEKIILGTEDELSTFSWLDTVTITQTGLFVAINRKKNMVVSFGDGVNFVIVLHQVWKKHPLHQDFLGFYVVDSHRMSARTHGLLGQFFRPFDFEVSDVRPGSDPAKPDATMVVKNHQLTVTRGSQRDYRKDASVGTKVTCWFVHNNGEGLIDGVHTDYIVPSLF
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H3, ITI heavy chain H3, ITI-HC3, Inter-alpha-inhibitor heavy chain 3.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_BACP2
Sequence: MFVDQVKVYVKGGDGGNGMVAFRREKYVPKGGPAGGDGGNGADVVFEVDEGLRTLMDFRYKRHFKADRGEHGMSKNQHGRNAEEMIVKVPPGTVVTDAETEQVLADLTEHGQRAVIAKGGRGGRGNSRFATPANPAPQLSENGEPGKERDVILELKVLADVGLVGFPSVGKSTLLSIVSSAKPKIADYHFTTLVPNLGVVETDDNRSFVMADLPGLIEGAHEGVGLGHQFLRHIERTRVIVHVIDMSALEGRDPYEDYVTINEELEQYNMRLTERPQIIVANKMDMPDAADNLAAFKEKLTDDYKVFPISAITREGLRELLFEIANQLETTPEFPLYNEEELSDNRVMYRFDEGDAPFEITRDPDGTFVITGKALERLFKMTDFSRDESVKRFSRQLRGMGVDDALRERGAQDGDIIRLLEFEFEFID
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_SALTY
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_SALCH
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQTQQTTQTTTTAAGSAADQGVPASGQGKMITVKTDVLDLTINTHGGDVEQALLPAYPKELGSNEPFQLLETTPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAFVLADGQNELQVPMTYTDAAGNTFTQTFVFKRGDYAVNVNYSVQNTGEKPLEVSTFGQLKQSVNLPPHRDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNVSSKGGWVAMLQQYFATAWIPRNDGTNNFYTANLGNGIVAIGYKAQPVLVQPGQTSAMTSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRQSQEMMALYKAEKVNPLGGCFPLIIQMPIFLALYYMLMGSIELRHAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REG3G_RAT
Sequence: MLPRVALTTMSWMLLSSLMLLSQVQGEDAKEDVPTSRISCPKGSRAYGSYCYALFSVSKSWFDADLACQKRPSGHLVSVLSGSEASFVSSLIKSSGNSGQNVWIGLHDPTLGQEPNRGGWEWSNADVMNYFNWETNPSSVSGSHCGTLTRASGFLRWRENNCISELPYVCKFKA
What is the function of this protein?
Has bactericidal activity against L. monocytogenes and methicillin-resistant S. aureus.
What are the official names of this protein?
Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 3, Regenerating islet-derived protein III-gamma, Reg III-gamma.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: T185L_DICDI
Sequence: MIENENTSLLSTSSSSTSSSPNNANSPSSLNIGISNSENGTPRKDNTSGNNSPSAQITKYNGIDISNNSSRNSSRPNSRSGYRGDSSSNNNNNNNNNNNNNNNNNNINKHNSIVYNKSNNKLNSIGGSNNDLQGGGGGNGNGNGNGSSKYKIGINNKDVEEKIEIKKQKKMNRTNNQKFWRIVGSILQIIGLSSIVFTIFIGLYIDGYIDWSYWILFIPVYVILAASYLATGSRVLSNLVSWIIRLVWRLSVFGLTVFVVFTIIHFKYNTFGFSVMMIPLLFTFGSVFVMGIFSLLFGIIFVDGKSTPQRKTKYIVNGLPLLFTGAILTPAAIMIALKLDGLYDAKLAVCFVSLFIGDIIASCFSFFLLIFSLGSKDTATFSIGQLLSIIFITICSIVFKVLLILATDQQHNINSLFLLIPLLVAEAFMVFCGINLFLRPPRVIVDNSEELAKSNMINNQDSSESESDDETEVSFKDREDEESEKLISNL
What are the official names of this protein?
Transmembrane protein 185-like.
What is the protein family that this protein belongs to?
Belongs to the TMEM185 family.