PharMolix/UniProtQA huggingface dataset:
Protein: T3HPD_SACKO
Sequence: MHTGGEPLRIVTDGFPKPDGKTILQKRRFVKEKLDNFRKLLMHEPRGHYDMYGALLVEPDIEDADIAVLFMDNRSYSTMCGHAVIALGRYATDYGYVRPTEPETKVNIECPCGLVKALVEYKNGKSGSVRFQSVPAFVFATDVELNVQGHGKVKVDISYGGAFYAFISADKLGLDLWKTPINQIKDAATMVTNAVKNEVQLEHPDDNDLAFIYGTIVTDGKDEYSDEPTANICVFADAQVDRSPTGSGVTARTALQYHKRHISLNKSRVFVNARIGSKFSAKPVRQTKCGSYDAVIIEVSGHAFYTGKSAFTFEEDDPLKGGFLLK
What is the function of this protein?
Catalyzes the dehydration of trans-3-hydroxy-L-proline to delta-1-pyrroline-2-carboxylate (Pyr2C).
What are the official names of this protein?
Trans-L-3-hydroxyproline dehydratase, Trans-3-hydroxy-L-proline dehydratase.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: MSRQ_SHIDS
Sequence: MRLTAKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLRSLFNRLRKQVHNKLSV
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYT_CLOD6
Sequence: MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEVVGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGFYYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELISDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIYGTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNELLKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCPGGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQIKDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPYTINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMIHRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIRVELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIASISKEIESRESIIQD
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_PSEAB
Sequence: MSSVRLPSVDRLLRSAAAAPLHQRYGREALLATLRDLLDELREPARHGALAEIELSEAVLAGRAGERLAAQHASRVRRVFNLTGTVLHTNLGRALLPDEAIEAITLAARYPLNLEFDLASGKRGDRDDLIAGLIRELTGAEAVTVVNNNAAAVLLALNSLGARKEGIISRGELIEIGGAFRIPDIMARAGVRLHEVGTTNRTHARDYEAAIGPRSGLLMRVHTSNYSVQGFTASVPTAQLAAIAHGHGLPLLEDLGSGTLVDLTRWGLPKEPTVQEALADGADIVTFSGDKLLGGPQAGLILGNRELIGRIKKNPLKRALRVDKLTLAALEAVLGLYRDPDRLAERLTTLRLLSRPAAEIRAQAERLAPALGEALGEGWEVAVVDALGMIGSGAQPVARLASAALCLRPRQPRRLRGRALRNLEEALRGLPLPVIGRLDDDALWLDLRQLDDEPAFLAQLPRLRSELS
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_YERPA
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGLSYSRFINGLKKASVEIDRKILADIAVFDKVAFSALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y1606_STRP3
Sequence: MMNMQNMMRQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFTGDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDEATKKTLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SpyM3_1606.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CALC1_ONCKE
Sequence: MVMMKLSALLIAYFLVICQMYSSHAAPARTGLESMTDQVTLTDYEARRLLNAIVKEFVQMTSEELEQQANEGNSLDRPMSKRCSNLSTCVLGKLSQELHKLQTYPRTNTGSGTPGKKRSLPESNRYASYGDSYDGI
What is the function of this protein?
Causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
What are the official names of this protein?
Calcitonin-1.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YR902_MIMIV
Sequence: MDNEYKNIDNKLKKEIGKFLTYNYSKNNNVVAIKYLGYVRLLNMNNSIRDLCMESSSKNMNDYNTFNNYVYNKIEELIYFMLDKYKKTEIESAGLRIIQIDKLCEELSLDAKKIVLDNLGIFDENFNYKKENSTAKLKFYLLFLLINHNKSCDKIALFNKMNNILKNFNPQYNVHSDPNVISFCDPNVISFCDTLVYNKLIDNKNLVALIKML
What are the official names of this protein?
Uncharacterized protein R902.
Protein: RECA_NITWN
Sequence: MSQAALRIVEGSSMDKSKALSAALSQIERQFGKGSVMKLGKNDKSMDVEVISSGSLGLDIALGVGGLPKGRIVEVYGPESSGKTTLALHAVAEAQKKGGICAFIDAEHALDPVYARKLGVNVDDLLISQPDHGEQALEIADTLVRSGAVDVLIIDSVAALVPRAELEGEMGDALPGLQARLMSQALRKLTASINKSNTMVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRIGAIKERDEVVGNQTRVKVVKNKLAPPFKQVEFDIMYGEGISKMGEILDLGVKAGIVEKSGAWFSYDSQRMGQGRENAKAFLRANPDITAKVEMAIRQNSGLIAEQILAGSPERETDDDETAED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNZ_LISMH
Sequence: MELVFLGTGAGVPSRGRNVTSIALSMLNERNAIWLFDCGEATQHQIMRSQIKLSKLEKIFITHLHGDHIFGLPGLLSSRSFQGGESDLTIYGPVGITEYVETSLRLSGTRLTYKIIFNEIEPGLIFEDKMFSITVDELDHGLRSFGYRIVEKDKPGALNADKLIEDGVEPGPIFQKIKKGETVTLADGSVINGKDYIDEPQKGKIISIFGDTKATASELELALNADVLVHEATFEGDKEKLAGEYMHSTTLQAASLAKKANVKKLILTHISSRYDRDASKELLIEAQSVFENTEIAYDLAVFPIGE
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: IF2_BURM1
Sequence: MASNNVAQFAAELKMPAGVLLEQLQAAGVQKASEDDALSEADKARLLDHLRKSHGATDGDKRKITLTRKHTSEIKQSDATGKARTIQVEVRKKRTFVKRDDVSDVAEQGQAQVAEADDDAELKRREEEARREAALLEKQAQELRERQERLEREEAERRAREEAAEAERRRAEEEAAAKRAAAEAAAAQQAAQQAAAAQQAAAPADSAQDEARAAAERAAQREAAKKAEDAAREAAEKARAEQEEIRKRREAAEAEARAIREMMNTPRKAVVKAVEPPKPAEPAKPAEAKGTLHKPAKPEGAQARPAAKKPAAAPAATPAPAGAGDRNKKPGGGKGGWQDDAAKRRGIKTRGDSSGGVDRGWRGGPKGRGRHQDNASSFQAPTEPIVREVHVPETISVADLAHKMAIKASEVIKVMMKMGQMVTINQVLDQETAMIVVEELGHRALAAKLDDPEALLVEGETGSDAEQLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVVTFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAISHAKAGGVPIVVAINKIDKPEANPDRVKQELVAEGVVPEEYGGDSPFVPVSAKTGAGIDDLLENVLLQAEVLELKAPVEAPAKGIVIEAKLDKGKGPVATMLVQSGTLSRGDIVLAGTAYGRVRAMLDENGKPTKEAGPSIPVEIQGLSEVPAAGEEVIVLPDERKAREIALFRQGKFRDVKLAKQQAAKLESMLEQMGEGEVQNLPLIIKADVQGSQEALVQSLLKLSTDEVRVQIVHSAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGIDIRYYNIIYDAVDEVKAAMSGMLAPEKREVVTGMVEVRQVFKVPKVGTVAGCMVTDGIVKRSSSVRVLRNNVVIFTGELESLKRFKDDVKEVKQGFECGMSVKNFNDILEGDQFEVFEVTEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPE_GLOBL
Sequence: YLTDHYFKVDLNSTVTQQRFLLDPSELAGITIMQPSDSNIEWLKQYRDDVATWLENS
What is the function of this protein?
Venom protein that cleaves N-terminal acidic residues from peptides with high potency in presence of calcium (PubMed:18384831).  It may have several roles in venom including alteration of blood pressure by cleaving circulating angiotensin-2, general degradation of host tissue, increase of permeability to other venom components, and/or processing of other toxins in the venom (By similarity) (PubMed:18384831).
What are the official names of this protein?
Aminopeptidase A, AP-A, APA, Glutamyl aminopeptidase, EAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Found in the venom as transmembrane proteins in exosome-like vesicles.
Protein: HIS6_BRUA2
Sequence: MTLKARVIPCLDVKDGRVVKGVNFVDLIDAGDPVEAARAYDAAGADELCFLDITASSDNRETIFDVVARTAEQCFMPLTVGGGVRQVADIRKLLLAGADKVSINTAAVKNPEFVAEAADKFGNQCIVVAIDAKKVSGAGENDRWEIFTHGGRQPTGIDAVEFAQKVVDLGAGEILLTSMDRDGTKAGYDVALTRAVADSVRAPVIASGGVGTLDHLVAGIRDGHATAVLAASIFHFGTYTIGEAKRYMAEAGIPMRLDPVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNFA_BUBCA
Sequence: MSTKSMIRDVELAEEVLSEKAGGPQGSRSCLCLSLFSFLLVAGATTLFCLLHFGVIGPQREEQSPGGPSINSPLVQTLRSSSQASSNKPVAHVVADINSPGQLRWWDSYANALMANGVKLEDNQLVVPADGLYLIYSQVLFRGQGCPSTPLFLTHTISRIAVSYQTKVNILSAIKSPCHRETPEWAEAKPWYEPIYQGGVFQLEKGDRLSAEINLPDYLDYAESGQVYFGIIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: ARGB_SULSY
Sequence: MESIIEKAEILLEALPFIRNFRGKTFVIKYGGNAMDKADLRDAFAQDIIMLKYIGINPVIVHGGGPQIGQYLKKMGLESKFVGGLRVTDKETMDIVEMVLGGLVNKSIVQLINSYSGGHVKAVGITGKDGCLIKAKKLDAEEYFRSIGDYRPTELLDLGHVGEVEEVNPELLIHLDEDNYIPVIAPIGFDAEGNAYNINADFVAAAIAGALKAEKVLFLTDIEGLKDENGNTLSSATVSQINQMIKDGVIKGGMIPKVKACIQALEKGVNKAHILDGRLPHCILLEIFTKKGVGTEITL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_CUTAK
Sequence: MADPSSYRPAPGTIPTQPGVYRFSDAHGQVIYVGKAKNLRNRLNSYFQDISALHPRTQRMVTTAAHVQWTVVQNEVESLQLEYTWIKEFDPRFNVMYRDDKSYPWLCFTWTDEYPRVFVGRGAHHKGWRYYGPFGQAWAIRDTVETLLRVFPMRSCSTGVFNRAKNQGRPCLLGYIGKCSAPCVERITSEAHREIADEFCDFMAGRTTKIVKRLESQMAEASENLEFERAAVIRDSLGALSKTLERNAVVLGDGTDADVISMALDPLEVGVKIFHVRGGRIRGERGWVADRADDADEAELMETFLTQLYGVNASDGQVRDDGHGNAVPPLVLVSAEPTNPDVMSTILSSERGSHVEIRVPRRGDKATLMDTVTRNAQETLAQHKLKRASDLATRTRALEEIQESLGLDRAPLRMESYDISHIQGTNVVGSMVVFEDGMPRKSEYRRFSIKGFEGSDDFAAMHEVLSRRLRRLIEDRDAMAAAQTPDGDVGSLIDPTTGSPRKFAYAPHLIVVDGGAPQVHAAQQVLEEFGLEDEIALCGLAKRLEEVWLPDEEWPVILPRTSEGLYLLQRLRDEAHRFAITFHRSKRSKAMVESVLDGVSGLGETRRKALVSHFGSVRSLRKATVDDIVEVPGFGPKLAGEVVAALSQDKPAEAINTATGEVVDANGPDAGR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR474_MIMIV
Sequence: MNISIESQLINYCLLFFTVVIIPIFYYIYKIVYLYLSHKLRESLINTSARIFKENESFVKQIIFTITDGVGNLRQDIMDHLQYRQTCNSIKYIVDKVFVLIDNISAIYSNTPVENYNYQYCDNITPVQPLGCGAYCPYYQPYDATFNPDCNLNYDTIYNFDFDKDIIKCDNTSECSETNETNKNTSHKLKFEYPKRCRKSRRNSRVFSRNFLKTKKSRENNSKTSTTEPFACTKDETTGMYTIKSNAYDTKNSTETNSDNNSEIVSETNSETNYSTPTTAKVNIDDVLAAMTTVYDKSDFGLNDKIKENVADSLKKMCDSSGNIKVDFDDQKLFKTVFDSVYQGLMTDPSIVDNSGYSSPTNESLNGSLTETLNESLNGSFDNSINNIKETLNKSLMDFIDCPSGSINFSNKN
What are the official names of this protein?
Uncharacterized protein R474.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GPMB_SHIF8
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: VPS34_YEAST
Sequence: MSLNNITFCVSQDLDVPLKVKIKSLEGHKPLLKPSQKILNPELMLIGSNVFPSSDLIVSLQVFDKERNRNLTLPIYTPYIPFRNSRTWDYWLTLPIRIKQLTFSSHLRIILWEYNGSKQIPFFNLETSIFNLKDCTLKRGFESLKFRYDVIDHCEVVTDNKDQENLNKYFQGEFTRLPWLDEITISKLRKQRENRTWPQGTFVLNLEFPMLELPVVFIEREIMNTQMNIPTLKNNPGLSTDLREPNRNDPQIKISLGDKYHSTLKFYDPDQPNNDPIEEKYRRLERASKNANLDKQVKPDIKKRDYLNKIINYPPGTKLTAHEKGSIWKYRYYLMNNKKALTKLLQSTNLREESERVEVLELMDSWAEIDIDDALELLGSTFKNLSVRSYAVNRLKKASDKELELYLLQLVEAVCFENLSTFSDKSNSEFTIVDAVSSQKLSGDSMLLSTSHANQKLLKSISSESETSGTESLPIVISPLAEFLIRRALVNPRLGSFFYWYLKSESEDKPYLDQILSSFWSRLDKKSRNILNDQVRLINVLRECCETIKRLKDTTAKKMELLVHLLETKVRPLVKVRPIALPLDPDVLICDVCPETSKVFKSSLSPLKITFKTTLNQPYHLMFKVGDDLRQDQLVVQIISLMNELLKNENVDLKLTPYKILATGPQEGAIEFIPNDTLASILSKYHGILGYLKLHYPDENATLGVQGWVLDNFVKSCAGYCVITYILGVGDRHLDNLLVTPDGHFFHADFGYILGQDPKPFPPLMKLPPQIIEAFGGAESSNYDKFRSYCFVAYSILRRNAGLILNLFELMKTSNIPDIRIDPNGAILRVRERFNLNMSEEDATVHFQNLINDSVNALLPIVIDHLHNLAQYWRT
What is the function of this protein?
Phosphatidylinositol 3-kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I.  This complex is essential to recruit the ATG8-phosphatidylinositol conjugate and the ATG12-ATG5 conjugate to the pre-autophagosomal structure.  Also involved in endosome-to-Golgi retrograde transport as part of the VPS34 PI3-kinase complex II.  This second complex is required for the endosome-to-Golgi retrieval of PEP1 and KEX2, and the recruitment of VPS5 and VPS7, two components of the retromer complex, to endosomal membranes (probably through the synthesis of a specific pool of phosphatidylinositol 3-phosphate recruiting the retromer to the endosomes).  Its activation by VPS15 may lead to the phosphorylation of phosphatidylinositol in the sorting compartment membrane.  Finally, it might also be involved in ethanol tolerance and cell wall integrity.
What are the official names of this protein?
Phosphatidylinositol 3-kinase VPS34, PI3-kinase VPS34, PI3K VPS34, PtdIns-3-kinase VPS34, Carboxypeptidase Y-deficient protein 15, Vacuolar protein sorting-associated protein 34, Vacuolar protein-targeting protein 29.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: DEOC_CLOBH
Sequence: MKLSKYIDHTLLKPQATEKDILKLIEEAKTYDFASVCVNPSWVKLAYENLKDTDVKVCTVVGFPLGATSTASKVYETKVAIKDGADEIDMVISVGQLKSGNDEYVKEEIKKIVEASKNKLVKVIIETCLLTEEEKVKACTLSKEAGADYVKTSTGFSTGGAKPEDIKLMRETVGKDMGVKASGGIHTREEMEVMIENGATRIGASCGVELVK
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_CLOBA
Sequence: MSVISMKQLLEAGVHFGHQTRRWNPKMAPYIFTERNGIYIIDLQKTVRKAEEAYNFIKEVSTEGKDILFVGTKKQAQDAIKDEAIRSSMHFVNNRWLGGMLTNFSTIKKRIRRLSEIERMQEDGTFEVLPKKEVIKLKGELEKLEKNLGGIKNLDCDNIGAMFVVDPRKEKNAISEAKILGIPVVAIVDTNCDPEEVDYVIPGNDDAIRAVKLITAKMADAIMEGRQGEELAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SSTT_SHIBS
Sequence: MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLGFALRHGNETTKNLVNDLSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQLLVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDDRLANSALRN
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCF12_PHAAC
Sequence: MELLIQLTSLLLIVIAGPLVIALLFLKQGNL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: THIO_STAA8
Sequence: MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity).
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: LPQV_MYCTO
Sequence: MRPSRYAPLLCAMVLALAWLSAVAGCSRGGSSKAGRSSSVAGTLPAGVVGVSPAGVTTRVDAPAESTEEEYYQACHAARLWMDAQPGSGESLIEPYLAVVQASPSGVAGSWHIRWAALTPARQAAVIVAARAAANAECG
What are the official names of this protein?
Putative lipoprotein LpqV.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: SYR_METS3
Sequence: MYFEIEKQAIDAISDALDKFEVDNTLENFQVEDEKNFRLEFPPNPDMGDLASTIAFSLAKKLRKAPNLIASEIVEKLEIPEIFEKVEAIGPYVNFFIDYSNFSKKLLEYVGKDYGHLPKADEKIILEHTSANPNGPLHIGHVRNSIFGDSLNRLLKVAGREVETQYYVNDMGRQIAIIVFGITELGLKIEDQEGDKIDHKIGRLYFKANQKLNEDESLVSHVDNLIERYEGGAEPELNKIFEEVVESCLLGIKETLHRININHDDFVWEGQFVRSGEVDDMIKYFDHEGFVSYGDVTYIDLTCFQIEKEFVLRRSDGTSLYSTRDLAYHRYKATQGDVVLDILGSDHKLAAQQINVIFKEILREIPPEVIFYEFITLPSGSMSTRKGVFVSVDELVDEAVKRAADEIKSRNPDLTDEEIKPMAEDIGVGAIRFFIAKLSPEKHLTFKWDEALSFERGCASIQYAHARACKLLKKSGKDVSSLAVSDDWVPNENEKDLIRTIAKFPQVIEDCANKKRIHNITQYCQDLAGAFNKFYKAEQVIGSDVEDTRLVLVDRAKTTLKNALDILGVPAPQKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCPS_SPORE
Sequence: MTRLYQPSQDWPACTLSYRHFHLLWTLPLCAVLFLVARPFLTKLDRAKLILLPIIAFVWTTPWDNLIVKNRAWFYHRHCIWFTIGYVPIEEYFFFVIQSLISTLWCTLLTRWALPNLYLVPSSPKRRRLATPAVVVCMLCFVLGLKAAVPETHSYYFGMITWWSSLPLALLLWGSVDFVSNMGVRAGLAPFALSVLAPTFYLWASDVYALRRGTWHINEATSLNVFPIPHLPIEEMLFFLVTNLILVSACFTFDRCVAICRQSVAENAPPLSPSYLPLGSLDTYTKLWAAFVRSDRPPVATSAASASVEPRDLAASLQVLRAASKSFNAASLLLPWDLRTDLGCLYAFCRVADDLVDDDAQGLEAKSSNLDVIRAIVDAIYADSPEAAPQKQPSAQPVSDRIRTLLAPVALPDKVKQDTRAAAASIAPLTRYIPKRLWYEMLQGYSLDLLFEHPDADKRTRLRTMDDLVEYSQCVAGVVGEMCTRVILGRCGGAVPLELKVDRTIAVPSTKAAMAGKALDLTRADDVHALLYEARRMGVSLQLVNIARDIVPDSVELRRCYLPTDMFDKQDARMQDALLAGHIAVRSQHTTTLEEKELVQPRDVRKYALRLLRVSRGLYDQAYPALAQIPNRPARAGLKAACSVYAAIGTRIEAQTETDVAEGRRARMSNRDRMLRAVSAVYFGV
What is the function of this protein?
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
What are the official names of this protein?
Bifunctional lycopene cyclase/phytoene synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ACCO_DIACA
Sequence: MANIVNFPIIDMEKLNNYNGVERSLVLDQIKDACHNWGFFQVVNHSLSHELMDKVERMTKEHYKKFREQKFKDMVQTKGLVSAESQVNDIDWESTFYLRHRPTSNISEVPDLDDQYRKLMKEFAAQIERLSEQLLDLLCENLGLEKAYLKNAFYGANGPTFGTKVSNYPPCPKPDLIKGLRAHTDAGGIILLFQDDKVSGLQLLKDGHWVDVPPMKHSIVVNLGDQLEVITNGKYKSVMHRVIAQTDGNRMSIASFYNPGSDAVIYPAPTLVEKEEEKCRAYPKFVFEDYMNLYLKLKFQEKEPRFEAMKAMETTGPIPTA
What are the official names of this protein?
Probable 1-aminocyclopropane-1-carboxylate oxidase, ACC oxidase, Ethylene-forming enzyme, EFE, Senescence-related protein.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.