PharMolix/UniProtQA huggingface dataset:
Protein: CFT1_NEOFI
Sequence: MQCYTELLPPSGVTHALAIPFISATAENLVVVKTSVLQIFSLLKVQHHLRGGTIEGKSARPDRVETTKLVLEREYPLSGTVVDICRVKILNPKSGGEALLLAFRNAKLSLVEWDPERHGISTLSIHYYERDDLTRSPWVPDLSSCGSILSVDPSSRCAVFNFGIRNLAILPFHQPGDDLAMDDYEFHLHQDDFNQVSDHVGNDLKSKDRTVYQTPYASSFVLPLTALDPSILHPVSLAFLYEYREPTFGVLYSQIATSHALLPERKDSIFYTVFTLDLEQRASTTLLSVPKLPSDLFKVVALPPPVGGALLIGSNELVHVDQAGKTNAVGVNEFARQVSAFSMVDQSDLALRLEGCVVEHLSDSTGDLLLVLSSGNMVLVHFQLDGRSVSGISLRPLPAQAGGTIMKSAASSSAFLGSGRVFFGSEDADSVLLSWSSMSSNPKKPRPRMSNVAEDREEASVDSQSEEDVYEDDLYTAEPETPALGRRPSAETSGVGVYIFQILDRLPNIGPLRDITLGKPASTVENTGRLIENACSELELIAAQGSGRNGGLVLMKREIEPDVAASFDAQSVQGVWTAVVALGSGAPLVPDEQRINQEYRQYVILSKPEAPDKEQSEVFIADKQDLKPFKAPEFNPNNDVTIEIGTLSCKRRVVQVLRNEVRSYDIDLGLAQIYPVWDEDTSDERMAVSASLADPYIAILRDDSTLMLLQADDSGDLDEVELDDSTRAGKWRSCCLYWDKAEIFSSTVPTSKQRTHCELFLFLLSIDCRLYVYRLPDQQLMSVIEGIDCLPPILSTELPKRSTTREVLSEAVIADLGESWNPSPHLILRTESDDLVIYKAFASSIKGESHTHLSFVKETNHTLPRVTTSDKEMQSNEELSRSRSLRILPNISDLSAVFMPGPSASFILKTAKSCPHVFRLRGEFVRGLSIFDLASPSLDKGFIYVDSKDVLRICRFPSETLFDYTWALRKIGIGEQVDHLAYATSSETYVLGTSHSADFKLPDDDELHPDWRNEVISFLPELRQCSLKVVSPRTWTVIDSYSLGPAEYVMAVKNMDLEVSENTHERRNMIVVGTAFAWGEDIPSRGCIYVFEVIKVVPDPEKPETDRKLKLIGKELVKGAVTALSQIGGQGFLIAAQGQKCMVRGLKEDGSLLPVAFMDMQCYVNVVKELKGTGMCIMGDAVKGLWFAGYSEEPYKMSLFGKDQGYLEVVAAEFLPDGDKLFILVADSDCNLHVLQYDPEDPKSSNGDRLLARSKFHMGHFATTMTLLPRTMVSSEKAMADPDSMEIDSQTISQQVLITSQSGSVGIVTSVPEESYRRLSALQSQLTNSLEHPCGLNPRAYRAVESDGTAGRGMLDGNLLYQWLDMGQHRKMEIAARVGAHEWEIKADLEAIGAEGLGYL
What is the function of this protein?
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Involved in poly(A) site recognition.  May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
What are the official names of this protein?
Protein cft1, Cleavage factor two protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DXR_LISMH
Sequence: MKKIILLGATGSIGTQTLAIIRENPEKFQVVALSFGRNMERGRAIIKEFKPKMVAVWHTRDRVTLEAEFPNVKFFNGLEGLREVATYLDGDVLLNAVMGSVGLLPTLDAIEAGKAIAIANKETLVTAGHLVMRAAKEKNISLLPVDSEHSAILQALNGENTERIEKIVLTASGGSFRDKTREQLSLVTVKEALKHPNWNMGNKLTIDSATMFNKGLEVMEAHWLFGVDYDDIEVVIQRESIIHSMVQFVDGSFIAQLGTPDMRMPIQYALTYPDRLYIPYEKEFRITDFSALHFEKVDYERFPALKLAYNAGKIGGTMPTVLNAANEIAVAGFLNGQVAFYNIEALVENAMNRHTSISDPDLDTILQVDQETRAYVKTLL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: LYTS_STAAB
Sequence: MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARCQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
What is the function of this protein?
Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism.  Participates also in sensing and responding to host defense cationic antimicrobial peptides (HDPs).  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of LytR.  In turn, LytR binds to the upstream promoter regions of target genes including lrgA and lrgB, to positively regulate their expression.  Possesses also a phosphatase activity that dephosphorylates and thus inactivates LytR.
What are the official names of this protein?
Sensor histidine kinase/phosphatase LytS, Autolysin sensor kinase.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 5DNU_ECOLU
Sequence: MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAKTRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase YfbR, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_STAPU
Sequence: MAHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKASQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGSETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: CYPD2_CATRO
Sequence: MDFEYLPFNLVTFFIFLFFVFLLIYGRRKSKRTXKINLPPGPWKLPILGNLHNMMMGSSPHHIFRDLSRKYGDLMLIKLGEFNTIVASSPRMAKEVLKTHDLSFLNRPIIQATKILCYDNSALVFSQYGDSWRQMRKIFVLELLSTKRVRSFQPIRQDEGSRLVSLIKESVGKSIDLSEKIKLYTTSMVARAAFGKVNDAGVTFLKLVTEAAEVAEGFDPADMFPSYKFLNVFFNSRSNLLKIHGKTDMILEEMIDEHIKSHQMGKKANGENGEEDVIDILLSIKDSGDLGISHWMNNVKALIFDMFSAGTETSSATVEWAMTELMKNPSVMRKAQDEVRQAFKGKKTIDESDLEELKYLKLVVKEVLRLHPFAPLLVPRECREACQIDGYDIPVKTRVFVNVWAIGRDEKYWKDPESFIPERFEDNSLDFTGNNFEYLPFGCGRRICPGMTFGLANVHLVLALLLYHFNWKLPPGVNDIDMAERPGLGASKKHGLVLVPSFYQPSF
What are the official names of this protein?
Cytochrome P450 71D2, CrCYP71D2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SECA_DINSH
Sequence: MLGLGTITKKVFGTPNDRKVKSVRPLVAKINALEPEFQALDDAGLIAKTEEFKQRIAAGESLDDLLPEAFANAREGARRALGLRAFDTQLMGGIFLHQGNISEMKTGEGKTLVATLPAYLNALTGKGVHIVTVNDYLARRDAEWMGKVYAQLGMTCGVVVPFQQEDEKHAAYAADITYATNNELGFDYLRDNMKSELSQMSQRGHHYAIVDEVDSILIDEARTPLIISGPSQDKSDLYVTIDKVIPELVEEHYTIDEKTRGVSFTDEGNEFLEDRLHALGILPEEQSLYDPESTTIVHHINQGLRAHKLFNKDQQYIVRNGEVVLIDEFTGRMTPGRRLSEGLHQALEAKEGVEIKPENVTLASVTFQNYFRLYDKLGGMTGTAATEAEEFAEIYGLGVVEVPTNRPIQREDEHDQIYRTVQEKFDAIVKTIKEAHAKGQPILVGTTSIEKSEYLSQLLKKEDVPHNVLNARQHEQEAQIVADAGKLGAVTIATNMAGRGTDIQLGGNVEMRVLQALAETPEANPDEIRTRIEAEVAENKRKVLEAGGLFVLATERHESRRIDNQLRGRSGRQGDPGRSAFFLSLEDDLMRIFGSERLDKVLSSLGMKEGEAIVHPWVNKSLEKAQAKVEGRNFDIRKQLLKFDDVMNDQRKTIFSQRMEIMETDDVAEITRDMRHQVINDLVDEFIPPKSYADQWNVEGLYAAILEKVGADTDVIKWAEEEGVDDEIIRERLEKASDEFMAAKAAQFGVENMRRIEKQLLLQTIDQKWREHLLTLEHLRSVVGFRGYAQRDPLNEYKTEGFQLFESMLDSLRVDVTDKLGKIRPLTEEEQQAMMRQIAAQQAAAQAANEAARQPQPAMAGAGAEAEEGTPAEGFVESDPTTWGNPGRNDRCPCGSGKKFKHCHGRYT
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RLMKL_SHEPC
Sequence: MLNFFAAAPKGFEYSLAQELTEFGATEIKESVAGVYFTAPLALAYRITLWTRLASRIVLVIYKGSCESAEQLYNAAYCIDWPAHFSNRNTFSIDFHGTGGFINNTQFGALKIKDAIVDRFRDDGDERPNVSRTDADFKVDAHFRNGVITIAMNFSGPSLHQRGYRSTTGEAPLKENLAANMLVRSGWQAAPTTLLDPFCGSGTVLIEAALMAADIAPGLQRNRFGFEHWRRHDKAVWQDIVAEAKARASLGVKRCEIKFYGSDIDSRLVALAKRNAENAGVLELIEFKVANALNIEPPAAEGYLITNPPYGERLGNVSELLQLYYQLGDKFKKEFGGWKVAMLCSDIELISSLKLKADKQMKMFNGALECAFNLYTLHANSTRRDTPVLPEGVDIADIAPAFANRIKKNAKQLEKWAQKEGIDSYRIYDADIPEYNVAVDKYLDYVIVQEYMAPATIPEAVTKRRLSDVLLALPAAIGINPNKIIMKTRERQKGTNQYQKLDERKLELITTEYGAKFKLNLTGYLDTGLFLDHRLTRRLVGQKAKGRRVLNLFSYTGSASVHAALGGAKSVTTVDMSNTYINWAKDNFALNGLQGKQYEFVQADCLQWIRDCNEQFDLIFIDPPTFSNSKRMEDSFDVQRDHVNLLGALVKLLSPTGELVFSNNKRKFKMDIETLTKMNIMVKNIDDITLPMDYKRNPHIHNTWLITHA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_BIFLD
Sequence: MKVSPSVKRICENCRVIRRHGRVMVICVNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: MIAA_STAAM
Sequence: MNKNKPFIVVIVGPTASGKTELSIELAKRINGEIISGDSMQVYKHMNIGTAKVTPEEMDGIPHHLIDILNPDDTFSAYEFKRLAEDLITDITNRGKVPIIAGGTGLYIQSLIYNYELEDETVTPAQLSIVKQKLSALEHLDNQQLHDYLAQFDAVSAENIHPNNRQRVLRAIEYYLKTKKLLSNRKKVQQFTENYDTLLLGIEMSRKTLYSRINKRVDIMLDHGLFREVQQLVEQGYESCQSMQAIGYKELIPVINGQMIYEDAVNDLKQHSRQYAKRQMTWFKNKMSVHWLDKENMSLQMMLDEITTQIK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: INT12_BOVIN
Sequence: MAAAVNLELDPIFLKALGFLHSKSKDSAEKLKTLLDESLARGIDSSYRPSQKDVEPPKISSTKTVSVKQEPKTSSSLPSGNNNGKVLTTEKVKKEGEKRPADKMKSDITEGADVPKKPRLEKPETRSSPITVQTSKDLAMADLSSFEETSADDFAMEMGLACVVCRQMTVASGNQLVECQECHNLYHQDCHKPQVTDKEVTDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPTVVSVAPAVKDPLVKKPETKLKPETTFLAFKRSEVKASTVVSGNSSSTNVSSSATSGLIGWAAFAAKTTSAGPSTAKLSSAAQNNSGKPATSSANQKPVGLTGLATTSKGGIGSKIGSSNSTSPTVPLKPPPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGSSSQLSGNGNSGTSGPSGSTTNKTASEPSTSPSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 12, Int12, PHD finger protein 22.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAAS1_HUMAN
Sequence: MRPEVGREPAALQPRQRPRSDHQLHRSPFTVPPRTPACRSPGPSPPIAVALEVKPQLEDAIGKLAAEAVAVRVFPLAVDDLESDVLVGRPRVEAQDGEILVVGAGLQEVLGRGALVDEVGVEDVELVSLHDLGRWVVKVVVRLVVLVPLEARVHAVEEARLAWPVLVGPQDGGCPGSARTAAGKSFHHLWPQGQWASKPRMNEGTPQCACR
What are the official names of this protein?
Putative uncharacterized protein encoded by CACTIN-AS1, Cactin antisense RNA 1.
Protein: POTA_MYCMS
Sequence: MENNILELRNVTKEYDGQVVLKGISFNVKEGEFITLLGPSGCGKTTILKIIGGSQKPNSGEILFEDKNLIPIPINKRQFNTIFQSYALFPHLNVFDNVAFGLTIKKTKKDIIEREVMRQIRQVGLEGYENKKIDELSGGQKQRIAIARALVMKPKVLLLDEPMAALDVKLRKTMQEELKRLQQDIGITFIMVSHDQEEALSMSDRIVVMNQGTIQQIGTPEEIYNEPENAWVANFIGSSNIITDGIFLEDNKIKFDGKVFECIDTNFGENESSIDIIIRPEDIIIKNPNNGFFNAKVIKTTFKGIHWEIVVETSKKRQWIIHTINEYDVDQQVSIKWKPANVHVMWKEVDN
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: REXO4_ASPFU
Sequence: MDVNNLSSNWKKLQETLKKQSASSSSKKRKTSDRETQNVTTKKQKIETIERKKSSLKKKRMSEGQEHGGDESAQEPMVKTISHKSSTATISEQSRTESKPTKVNEGRSPTAEIGKYVAMDCEMVGVGPNPDNDSALARVSIVNFNGEQVYDSYVRPKEMITDWRTHVSGISPKHMAEARSLEQVQKDVAEILDGRILVGHAVSNDLDALLLGHPKRDIRDTSKHPPYRKIAGGGSPRLKILASEFLGLNIQDGAHSSVEDAKATMLLYRRDKEAFEREHLKKWPIRVVVDKKENGEDQKKKKKKKKPRKR
What is the function of this protein?
Exoribonuclease involved in ribosome biosynthesis.  Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
RNA exonuclease 4.
What is the protein family that this protein belongs to?
Belongs to the REXO4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NHR28_CAEEL
Sequence: MIIGKSPCSVCGEAGDGAHFGAEACRACAAFFRRSVALNKAYVCRAMGTCVIQKNVRCMCRACRFTKCIAVGMRKSAVQRHRELFASQETSSESSSNPRISPTLSWPMDISPQSYEETGMPTLSQLNENYNQMSTVRRVIHNTGGDNIFHRREPKAVAYTDAHNVHLKEIGLVADWIIKSYPDFEQLHQEQKKLLYRNFFLPFMILECGYMCCLNNRTDILFLPSGDYIDCNRPETFYGHRIKSHLISPNEAVRMFGPSFEIYRRNVLDPMRRENVDNFEFFTLCSLVLWDHGLEGQTEECVQMARCNRERILREVLYYYRRVKQISDPSMRLANLLVLLPALQRSVRRFQEDVEITHVFNVYSVEETFYELVSGRLSDSFFQTTQLTTSVEEEKVIKTEEIDSVWDLNKGQLVEMYEFPTPPLHTPTEMDPSTTQL
What is the function of this protein?
Orphan nuclear receptor.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-28.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENO_THENN
Sequence: MEIVYVEIVDVRAREVLDSRGNPTVEAEVVLEDGTVGRAIVPSGASTGKFEALEIRDKDKKRYHGKGVLKAVENVNETIAPALIGMNAFDQPLVDKTLIELDGTENKSKLGANAILAVSMAVARAAANYLGLPMYKYLGGVNAKVLPVPLMNVINGGQHADNNLDLQEFMIVPAGFDSFKEALRAGAEIFHTLKKILHDSGHVTAVGDEGGFAPNLSSNEEAIKILIEAIEEAGYKPSEQVFIALDCAASSFYDEEKGVYFVDGEEKSSEVLMGYYEELIAKYPIISIEDPFAEEDWDAFVEFTKRVGNKVQIVGDDLYVTNVKRLSKGIELKATNSILIKLNQIGTVTETLDAVELAQKNNMTAIISHRSGESEDTFIADLAVATNAGFIKTGSLSRSERIAKYNQLLRIEEELGKVAEFRGLSSFYSIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MTNA_AQUAE
Sequence: MDIRTHLGINQELSGKPVKVAEGYAEVLLKTQESMKADDKGLVHGGFIFSAADYASMLAVNHPNVVLAGANVKFLKPVKVGDEIICKARVSEDKGKKKKVLVECFKGEDKVFEGEFFTVFLIDMFWRGEKMEVKPFYWKGDKLLLLDQRKLPHQEVWLELKTYEEVAKAIKEMAVRGAPAIGCTAAYGFVLGVKVQKEDPEKVYETLKNTRPTAYNLFWALDRMMKALKEGKDIEEEAKEIEKEDYEANKRMGEIGSEIVPLNAKVLTHCNTGALATAGWGTALGVIRSAHYGGKNIFVWVDETRPYLQGARLTAWELVKESIPHKIITDSTAGFLMKKGMVDLVIVGADRITAKGDVANKIGTYTLAVLCKEHNVPFYVAAPTSTIDSNIKSGEEIIIEERSPEEVKVCGGCAIAPKESDALHLAFDITPAELITGIITEKGIFKPERITEALKD
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: ATPE_CUCSA
Sequence: MTLNLSVLTPNRIIWDSEVKEIILVTNSGQIGVLPDHAPIATAVDIGILKIRLTPNDGWLTMALMGGFARIGNNEVTILVNDAEKASDIDPQEAQQTLEIAEANLRKAQGKRQTIEANLALRRARTRVEAINGVPS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TLR2_CRIGR
Sequence: MLHVLWTFWILVAMTDLSRKGCSAQASLSCDAAGVCDGRSRSFTSIPSGLTAAMKSLDLSNNKITSIGHGDLRGCVNLRALILQSSGINTIEEDAFSSLSKLEYLDLSDNHLSNLSSSWFRPLSSLKYLNLLGNPYRILGETPLFLNLTHLQTLRVGNVATFSGIRRTDFAGLTSLDELEIKALSLQNYEPGSLQSIQSIHHLTFHLSQSDFLLGVFEDTLSSVGYLELRDANLDSFYFSELSTDEMNSPMKKLAFQNADLTDESFNELLKLLRYTPELLEVEFDDCTLNGVGDFQPSESDVVRELGKVETLIIRRLHIPRFYSFYDLSTVYTLLEKVKRITVENSKVFLVPCLFSQHLKSLEFLDLSENLMVEEYLKNAACEGSWPSLQTLILRQNRLKSIERTGKILLTLKNLTALDISRNSFQSMPDSCQWPGKMRFLNLSSTGIQAVKMCIPQTLEVLDVSNNNLISFSLFLPLLRELYISRNKLHTLPDASLFPVLLVMKIRENAISTFSKDQLSSFPKLVSLEAGGNHFICSCELLSFTLEHPALVQVLAGWPDSYLCDSPSRLRGQRVQDARPSVLECHQTLLVSGVCCALVLLILLIGGLCHHFHGLWYLRMMWAWLQAKRKPKKAPCRDICYDAFVSYSEQDSYWVENLMVQQLENSEPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTLFVLSENFVRSEWCKYELDFSHFRLFDENNDAGILVLLEPIEKKAIPQRFCKLRKIMNTKTYLEWPLDEGQQEVFWVNLRTAIKS
What is the function of this protein?
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components.  Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  May also promote apoptosis in response to lipoproteins.  Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).
What are the official names of this protein?
Toll-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Protein: MTNA_PSEAE
Sequence: MRERLLAAERVKAIEWRDGTLRLLDQRLLPQEEVWLEHESAAEVAKAIRDMVVRGAPAIGISAAYGIVLGARARLAQGGDWRAALEEDFRLLADSRPTAVNLFWALNRMRDRLERMKEGDQPLAVLEAEAISIHESDREANLTMAQLGMELIRKQQGSPQNILTHCNTGALATGGFGTALGVIRAAHLEGLVNRIYADETRPWLQGSRLTAWELANEGIPVSLNVDSAAAHLMKTENITWVIVGADRITANGDVANKIGTYQLAVNAMHHGVRFMVVAPSSTIDMNLESGEDIPIEERDGRELLEIGGRRVAAEVDAYNPVFDVTPADLIDAIVTERGVVERPDAERMAALMSRKRLH
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: RS13_PYRAB
Sequence: MADFRHIVRVAGVDLDGNKQLRWALTAIKGVGINFATMVCRVAGLDPFMKAGYLTDEQVKKIEEILQDPVAHGIPRWAVNRPKDYETGRDLHLITAKLDMAIREDIMRLRRIRAYRGIRHELGLPVRGQRTRSNFRRGQTVGVSRKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MIAA_RENSM
Sequence: MARISNAIGINPPIVIAVVGATGTGKSELSLALAEQIGGEIINADSMQFYRGMDIGTAKLTLAERRGIPHHLLDTLEIAEEASVARYQEQAREAIEDIQSRGLHPILVGGSGLYLRAALDVLEFPGTDPQLRRRLESELADSDIAKFRDRLRLVDSISEKRIGDEKRLVRALEVYELTGRPFSSFMPQREYVQPTFQIGLNGDRAGLHERLARRVHSMVEAGLPEEVAGLALRGLSDGKTASRALGYLQFLRTMSEPDYSRGQAAEDTIIATRQFARRQITWFTADPRVQWLDYASPELPALAKEMLSRF
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ASSY_PROM2
Sequence: MQQVKKVVLAYSGGVDTSVCIPYLKKEYGISEVITFVADLGQGEDLELIRQKALNSGASQSIVGNLVNSFVERYAFPAIRANALYLDKYPLSTALARPLIAENLVNIAREFSADAVAHGCTGKGNDQVRFDLAINALGPDLKIITPAREWNMSREEAIIYGEKFGIPAPVSKKSPYSIDVNLLGRSIEAGILEDPMQEAPEDIFAMTSSIDNSPDSPLDIEIIFKNGFPVGINDEFLTPVEIIKKANVLAGEHGYGRIDMIEDRVVGIKSREIYETPGLLLLIKAHKELESITLNPDIVDFKGIVEKKWGQIVYQGFWFGPLKDSLDAFISSTQTSVNGRVKIRLYKGNAIVIGRMSENNSLYRDDLATYSKDDVFKHSLAEGFIYMWGMSNKIWAELNSKTTD
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.