PharMolix/UniProtQA huggingface dataset:
Protein: SRRM4_MOUSE
Sequence: MASLQQGEKQLFEKFWKGTFKAVATPRPESIIVASITARKPMPRTEPQSSLLLPDQDGPSEKLGQHLAPEALGTNSWGREKACRELDPARAHSASQDRDPTPPPSSRGKKKKKKSTRKKRRRSPSYSPSPVKKKKKKSSKKHKRHRSFSKKRRHSSCSPKSKRREEKRHKKQSRSRKSHRHRHHRCPSRSQSSELRSPSCESRHRGRSPEEGRKSRRTHSRRCSKNHCKVSPDARSSHLPSQPLPRLGFLSARGVITGSGSAADLFSKSASPLAATRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPGGDLSKSRDLNCGNTSDSGNSFTTSSPQNKGAVLETVSPACRSRESRGFQSPCLQCAEVKKSSLVPSTARSSPIKECSRSSSYTSTRSSSPSSRSPNPRASPRYTRSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDLKYGEKEPQPRERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSSSLSSASSWYSSSSSSSSSSSRSPSRSYSRSRSPSRSHSSRSQTRSRTRTSRSSSSRSLSLGSRSRSRNRSLSYSSAESYASTRR
What is the function of this protein?
Splicing factor specifically required for neural cell differentiation.  Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation.  Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2.  Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (PubMed:19737518).  Promotes alternative splicing of REST transcripts to produce REST isoform 2 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells (PubMed:21884984).  Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system.  Regulates alternative splicing events in genes with important neuronal functions (PubMed:25838543).
What are the official names of this protein?
Serine/arginine repetitive matrix protein 4, Neural-specific serine/arginine repetitive splicing factor of 100 kDa, Neural-specific SR-related protein of 100 kDa, nSR100.
What is the protein family that this protein belongs to?
Belongs to the nSR100 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LOLD_PSESM
Sequence: MSDKAVLSCRNLGKSYEEGPESVVVLSGLQLELHPGERVAIVGTSGSGKSTLLNLLGGLDTPSEGSVWLAGEELSALGEKARGLLRNRALGFVYQFHHLLPEFTALENVCMPLLIGRTAIPEARQRATALLERVGLGHRLAHKPSELSGGERQRVAIARALINQPGLVMLDEPTGNLDHHTAQGIQDLMRELSTSSRTAFLIVTHDMSLARQMDRILRLEGGRLVEA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ARGC_METTP
Sequence: MIDIGIVGGSGYTGGELLRLLSVHPSANVVCVTSRKLAGKPVTSVHQHLRGLLDLRFEAPSPAEIAQRCDVVFTAVPHGTAMDWVPELLDNGAKVIDLSADYRLPVDVFEKTYGIKHRAPRDAVFGLPELHPEVAGASLVGNPGCYPTGATLAIAPLAKAGMVDRVVFDSKSGISGAGAEPTETSHYPNLAENIRCYRVTNHRHVPEIKQELSRLQNDIRISFTPHVIPAVRGILTTAHVFVKDSFQDTIQDREFISKLYSDFYRNAKFVRLVEGVPMLGNVRCSNFCDIGFEIEKNSDRIVVISAIDNLVKGASGQAIQNMNLMMGLDETAGLWFPGGAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_STAHJ
Sequence: MSAIIEAKKQQVDVIAEQLKNSVSTVIVDYRGLTVAEVTELRSQLREAGVEYKVYKNTMVRRAAEQAGIEGLDEFLTGPTAVATSTEDVVAPAKVIAGFAKEHEALEIKTGVMEGSVISAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAVGEQKEESAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: FZD2_RAT
Sequence: MRARSALPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQGCEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGTPALLTTAPPSGLQPGAGGTPGGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSHHHTRFARLWILTWSVLCCASTFFTVTTSLVAMQRFRYPERPIIFLSGCYTMVSVAYIAGFVLQERVVCNERFSEDGYRTVGQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKWGHAAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNRLDPLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEPLERLMVRIGVFSVLYTVPATIVIACYFYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRTSPDFTVYMIKYLMTLIVGITSGFWIWSGKTLHSWRKFYTRLTNSRHGETTV
What is the function of this protein?
Receptor for Wnt proteins.  Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (By similarity).  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.  Activation by Wnt5A stimulates PKC activity via a G-protein-dependent mechanism.
What are the official names of this protein?
Frizzled-2, Fz-2, rFz2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: IPYR_LEGPN
Sequence: MSLMEIPSGRDVPNEVNVIIEIPMHGEPVKYEVDKKTGALFVDRFMTTAMFYPTNYGYIPNTLSEDGDPVDVLVITPVPLISGAVISCRAVGMLKMTDESGVDAKILAVPTTKLSKMYQSMQTYQDIPQHLLLSIEHFFKHYKDLEEGKWVKVEGWVGPDAAREEITSSINRYNHIKK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_EXISA
Sequence: MAYSKLGRTSSQRKALLRDLATDLIINERIQTTEQKAKELRPVVEKLITLGKRGDLHARRQVASFVRKENAGEKDAIQKLFEDVAPRYAERQGGYTRIMKVGPRRGDGAEVVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: DNLJ_CHLMU
Sequence: MRALSQDYYIALCTELIEHDRRYYVLDRPTISDYSYDMKMRELQKIEAQHPEWKVPWSPTIYLGDRPSGQFPVVPHSHPMVSIANVYSLEELEEFFSRTEKLLGYFPTYSLELKIDGIAVAIRYENRTFAQALSRGNGVKGEDITANVSTIRSLPMTLPQDAPEEVEVRGEVFLSYQAFEKLNICQREQGKLEFANPRNAAGGTLKLLSSREAAKRNLDLSIYGLITNREEHSHFENLGLCAHWGFPIAGMPKQCRTKEEVIERIREVEGMRSRLPMAIDGVVVKVDSVAEQHRLGLTSKHYRWAIAYKYAPERAETILQDITVQVGKTGILTPVAELTPVLLSGSRVSRASLYNEDEIEKKDIRIGDSVYVEKGGEIIPKIVGINLAKRSPDSKPWKMPSLCPMCHNPVIKERVSVRCTNPLCLGGMLEKICFFASKGALNIDHLGEKVIAKLFEMGLIRSCSDVFALTENDLKQVPGFKDRSVHNLLASIAGAKEVTLDRFLTALSIPFVGSSGAIALADHFGTLDKVMKASLDELLSIEGIGQKVAASIIDFFSKTENVEEICRMQELGVRILPKQVDRWAPLQGKIFVLTGTLQEMTRLQAEERIRSLGGKISSSVSKNTYAVVVGREAGSKLKKAQELGVQVLEESDLLKILNQN
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ENO_BACAH
Sequence: MSTIIDVYAREVLDSRGNPTVEVEVYTESGAFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVMNAVNNVNEAIAPEIVGFDVTDQAGIDRAMIELDGTPNKGKLGANAILGVSMAVAHAAADFVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQEFMILPVGAPTFKESIRMGAEVFHALKAVLHDKGLNTAVGDEGGFAPNLGSNREALEVIIEAIEKAGYKAGENVFLGMDVASSEFYNKETGKYDLAGEGRTGLTSAEMVDFYEELCKDFPIISIEDGLDENDWDGHKLLTERIGDKVQLVGDDLFVTNTQKLAEGIEKGISNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAKYNQLLRIEDELGEIAVYDGIKSFYNIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: FYV4_ASHGO
Sequence: MLQTRLFHACAALARAASRPVPKPTSEIPDVSTFLAKIGRQCSEHAELYENKWENLFMWDGPKLKEKGVPVQQRRYILQQVERLRQGGPVREIREGKKSFFGGERKRKEKVAKWRAEQRHAA
What is the function of this protein?
Involved in telomere length regulation.
What are the official names of this protein?
Protein FYV4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS41 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MTCP1_MOUSE
Sequence: MAREDVGAPPDHLWVHQEGVYRDEYQRTWVAVVEEETSFLKARVQQVQVPLGDATKPSHLLTSQLPLMWQLYPEERYMDNNSRLWQIQHHLMVRGVQELLLKLLPDD
What is the function of this protein?
Enhances the phosphorylation and activation of AKT1 and AKT2.
What are the official names of this protein?
Protein p13 MTCP-1, p13MTCP1, Mature T-cell proliferation-1 type B1, MTCP-1 type B1.
What is the protein family that this protein belongs to?
Belongs to the TCL1 family.
Protein: METK_STAEQ
Sequence: MTYNKRLFTSESVTEGHPDKIADQVSDAILDEILKDDPNARVACETTVTTGMALISGEISTTTYVDIPKVVRETIKDIGYTRAKYGYDSQTMAVLTAIDEQSPDIAQGVDKALEYRNDISEEEIEATGAGDQGLMFGYATDETDTYMPLPIFLSHQLAKRLADVRKDEILDYLRPDGKVQVTVEYGEDDKPRRIDTIVVSTQHAEDVELAQIEKDIKTHVIYPTVDKALLDDETKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLAKQCEVQLAYAIGVAEPVSISINTFDTGKVSEARLVEAVRKHFDLRPAGIIKMLDLKQPIYRQTAAYGHFGRTDVLLPWEKLDKVNVLKDAVEIQ
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZGLP1_HUMAN
Sequence: MTEPQVGCVACPRVHKEPAQVGTPWPAKPRSHPRKRDPTALLPRSLWPACQESVTALCFLQETVERLGQSPAQDTPVLGPCWDPMALGTQGRLLLDRDSKDTQTRISQKGRRLQPPGTPSAPPQRRPRKQLNPCRGTERVDPGFEGVTLKFQIKPDSSLQIIPTYSLPCSSRSQESPADAVGGPAAHPGGTEAHSAGSEALEPRRCASCRTQRTPLWRDAEDGTPLCNACGIRYKKYGTRCSSCWLVPRKNVQPKRLCGRCGVSLDPIQEG
What is the function of this protein?
Transcriptional regulator that plays a key role in germ cell development.  Determines the oogenic fate by activating key genes for the oogenic program and meiotic prophase entry.  Acts downstream of bone morphogenetic protein (BMP) by regulating expression of genes required for the oogenic programs, which are repressed by Polycomb activities in sexually uncommitted germ cells.  Regulates expression of STRA8, a central downstream effector for the meiotic program.  Acts independently of retinoic acid (RA).  In males, not required for germ-cell sex determination, but required to allow the spermatogonia to efficiently accomplish the meiotic prophase.
What are the official names of this protein?
GATA-type zinc finger protein 1, GATA-like protein 1, GLP-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH4_DESVM
Sequence: MEDVQNSPAQVAMPIDRVGVKNLKLPLVVRDRAQGSQHTVATVDIGVDLPAEFKGTHMSRFVEALENWSEELDYNSMKRLLEDVKERLHARKAYALFRFPYFVRKGAPATASSGLVWYECRLTGELGDGKPSFLLELEVPVMTVCPCSKAISDEGAHSQRAVVRMSIRMTGFSWMEEFIDLAEAAGSSPVYTLLKREDEKFVTEDAFAHPTFVEDVVRAAAQRLEGHPHVAWFRVEVESFESIHCHNAFASIEREVRKG
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: TCEA2_TULGE
Sequence: MSVASFFSSLPARPFGYKDGRGRTGMVSTTDIGRRMVKPPVLACRPIESNTYHGSVFLTKSSRSPSPSLSPTPTALDDEIVLDLKPFLIIYKSGRIERFLGTTVIPACPEVATKDVVIDPATGVSVRLYLPNVVDLPSKKLPVLVYFHGGGFVIENTGSPNYHNYLTLLAAKAGVLIVSINYRLAPEYPLPASYDDCMAGFNWVVSHSAGPALEPWLAQHGDFSQILLSGDSAGGNVTHYVAMRADAGVIEGVAIVHPYFLGSEPVGNEINDPANIEFHDKLWRLAAPDTEGLDDPLINPVAPGAPILAGLKCKRAVVFVAGNDFLVERGRMYYEALVKSGWGGEAELVQHEGVGHVFHLSDYSGDISVAMMTKLIAFLKGE
What is the function of this protein?
Lactone-forming carboxylesterases, specifically catalyzing intramolecular transesterification, but not hydrolysis.  Involved in the biosynthesis of tulipalins, defensive chemicals that show antimicrobial activities against a broad range of strains of bacteria and fungi.  Substrates are 6-tuliposide A > 6-tuliposide B.
What are the official names of this protein?
Tuliposide A-converting enzyme 2, chloroplastic, TgTCEA2.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GUAA_ASPFU
Sequence: MAEEQNPSATFDTILTLDFGSQYTHLITRRLREIGVYSEMLPCTQKLADLPFKPKGIILSGGPYSVYEDGAPHADPAVFELGVPVLGICYGLQEIAYRLGKDNVVAGTAREYGHADLNAQRLDNQGHVDKLFAGLEEHVKVWMSHGDKLVKLPEGFHTIATTANSEYAGIAHETKPVYGIQFHPEVTHTPDGAKLLRNFAVDICGANPNWTMSKFVDQEILRIRKLVGETDHVLGAVSGGVDSTVAAKLMKEAIGDRFHAVLVNNGCMRLNECETVAETLNKHLGINLTVVDASKRFLDGLKGVTDPEKKRMFIGATFIDVFEEEAEKIEALAENSGAKVKWFLQGTLYPDVIESISFKGPSATIKTHHNVGALPKRMIEGQGMKLIEPLRELFKDEVRQLGRELGIAHELVMRHPFPGPGIAIRVLGEVTPERVDIARKADHIFISMIREAGLYDKISQAYAALDPSKAVGVMGDKRVYAEIIILRAVETTDCKLTLGIDGDFVLRYIISVMTARAFPFDNEFLSKCATRIINEVHGVSRVLYDISSKPPATIEME
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_PARL1
Sequence: MKLILLGPPGAGKGTQAKRLEEAHGLVQLSTGDMLRAAVAQGSEVGKVAEGIMARGELVPDDVVVGIIADRIEQPDAVNGYILDGFPRNVAQAEALDKMLAGKGTTLDAVVELGVDDSILLKRIETRAAETAGGPRADDNAEALAKRLKVYHEQTAPLIAYYKAKGKLRTVDGMKSMDEVTGQIETVLGISKRKGSWLSRLTGKK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF01_ARATH
Sequence: MKLSVRFISAALLLFMVFIATGMGPVTVEARTCESKSHRFKGPCVSTHNCANVCHNEGFGGGKCRGFRRRCYCTRHC
What is the function of this protein?
Confers broad-spectrum resistance to pathogens.
What are the official names of this protein?
Defensin-like protein 1, Low-molecular-weight cysteine-rich protein 68, Protein LCR68, Plant defensin 2.3.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y629_GEOSW
Sequence: MSNQLYVLAEQLEQAIRTSSDFQQLKQAYEAVRRDETAYRLFTNFRNLQMRLHEKQMTGAEILPEEIEQAQKAMALTQQNEKLAQLMTLEQRMSMVLSDIQQITMKPLEELYRSFAE
What are the official names of this protein?
UPF0342 protein GWCH70_0629.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: ATP6_ACIBS
Sequence: MAAEEHALTSPEYIKHHLTNMTYGKMPDGTWKLAETAEEAHSMGFTAIHLDSMGWSIGLGVIFCLLFWIVARAANAGVPTKFQSAIEMIIEFVDSSVRDTFHGKSRLIAPLALTIFVWIFLMNLMDLIPVDWIPQVAAFVGANAFGMDPHHVYFKIVPSTDPNITLGMSLSVFVLILFYSIREKGVGGFVGELALNPFNPSNPVAKALLIPVNLILELVTFLARPISLALRLFGNMYAGELIFILIALLPFWIQWALSVPWAIFHILVITLQAFIFMMLTIVYLSMASEKH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELD_BORBR
Sequence: MNTPVRLTQYSHGAGCGCKISPKVLEIILAGSGAQNLDPRLWVGNASRDDAAVYALDDQRGVVSTTDFFMPIVDDPFDFGRIAATNAISDIYAMGGDPLLAIAILGWPVNVLPPEVAREVVRGGRAACDEAGIALAGGHSIDAPEPIFGLAVTGVVDKARLKRNDTATAGCRLYLTKPLGIGILTTAEKKSRLRPEDVNLARDWMCTLNKPGSRFGALAGVKAMTDVTGFGLLGHLVEMADGSGVSARIEYAKVPRLPGVEHYLAEGCVPGGTGRNFDSYGARIAPLPQDRVDLLCDPQTSGGLLVAVEPAGEAEFLAAAGELGLRLEPIGELVAQRPYAVEVL
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: P34_RICRS
Sequence: MDTNSRNRLIKSASYLSVTTALIILSIKLYAWVVTDSQSILAALIDSMLDITSSFINLIALRFALQPPDHHHRFGYEKLQDLTIFSQSIFFFASAFFVGFSSVKSLFEKTKPENISDGTTVMYVCIFLTIILVFYQTYVIKKTGSEIVKADKLHYFTDLLTNVIVIISINLSDYFWFVDPLFGVVISLYIFHSSYSLFKKAFKNLVDHELPEQDRQKIISIVNNHLGAKGMHEMKTRYAGQKAFIQCHLEMDGNMSLYNAHKISDEIAFEILQEFPEAEIIIHQDPFGIEEHVKYREYIVR
What are the official names of this protein?
Protein p34.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FY_ARATH
Sequence: MYAGGDMHRGSQMPQPPMMRQSSASSTNINPDYHHPSGPFDPNVDSFGAKRMRKHTQRRAVDYTSTVVRYIQARTWQRDSRDRTTLQPTPAAAVDMLPTVAYSDNPSTSFAAKFVHASLNKNRCSINRVLWTPSGRRLITGSQSGEFTLWNGQSFNFEMILQAHDQPIRSMVWSHNENYMVSGDDGGTLKYWQNNMNNVKANKTAHKESIRDLSFCKTDLKFCSCSDDTTVKVWDFTKCVDESSLTGHGWDVKSVDWHPTKSLLVSGGKDQLVKLWDTRSGRELCSLHGHKNIVLSVKWNQNGNWLLTASKDQIIKLYDIRTMKELQSFRGHTKDVTSLAWHPCHEEYFVSGSSDGSICHWIVGHENPQIEIPNAHDNSVWDLAWHPIGYLLCSGSNDHTTKFWCRNRPADNPRDVLMQNQGYNEQGFGRQPDNFQPSEASPIPGAFVPGLTRNEGTIPGIGIAMPFDASSQGDHKQPLPGSMALGAPPLPPGPHPSLLGSGQQQGYQQQQQHQGHPQQMLPMPNMPHHQLPPSSHMPLHPHHLPRPMQMPPHGHMPPPSMPMSHQMPGSMGMQGGMNPQMSQSHFMGAPSGVFQGQPNSGGPQMYPQGRGGFNRPQMIPGYNNPFQQQQQPPLPPGPPPNNNQQHQ
What is the function of this protein?
Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels.  Required for the negative autoregulation of FCA expression.  Acts probably as an RNA 3' end-processing factor.  Required for growth and development in plants.
What are the official names of this protein?
Flowering time control protein FY.
What are the subcellular locations of this protein?
Nucleus.
Protein: NEP_I83A5
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGKAVMRMGDLHSLQSRNGNWRRQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEMRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SYY_PYRCJ
Sequence: MDVEERLSLVLRYPTEEVITVEELRELFQGGYKLNHYIGFEISGFIHIGTGVVSMSKVVDLQRAGVRTTVFLADIHSWLNNKLGGDLDTIRRVAVTYYVETFKRIIEVLGGDPDATRFVLGSDLYHHNDEYWFLLMDITRHLTLSQVRHSLTILGRKMGESIPLAYLVYPPLQVADVFALGAHIPHGGIDQRRAHILARQVADKIRFYPLTVDGKRIKPVALHHRLLPALNISSKPSSKEELSELKMSKSIPQSAIFVHDSPEEIRQKVAKAYCPPREVEYNPVLELLRIAAFREERKTPLVIKRPEKYGGDVEVWKYEELEAMYKEGKIHPADLKAVTAEALAALLEPVYKFFQGPGAKLLEEMRNIAITR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_HAEI8
Sequence: MSQGNLYILSAPSGAGKSSLISALLASDSSTQKMVSVSHTTRAPRPGEVEGVHYYFVSKEEFESLIEQDLFLEYAKVFGGNYYGTSLPAIEENLAKGIDVFLDIDWQGAQQIRKKVPSVKSIFILPPSLPELERRLIGRGQDSEEVIAERMSKAISEISHYDEYDYVIVNDDFEKTLKDLQSILQSERLTKDYQQKQNAMLIQQLLAK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4UE_SINFN
Sequence: MGDGPNWRSLPEPSRFVGSDPSPPVPRAPGGDTCPVGLAVIDAPWGVRAGPVLFRAPVQGSAKIAVARMLERGEGMTDQRHCYAGVDWASESHHVFLTDGDGRKIGERVFRHGGEGLAEMAAWLMATSGAVEGDEIQVAIEVPHGPVVETLIERGFKVNAINPKQMDRFRDRFTMAGAKDDSRDAEVMASALRTDPRCFRLLAVSDPVVIELREWSRIAEDLSAERNRLTNRMREQLWRYFPALLELENDLGAEWLLDLWDTVPTPDKAARIREATIAKLLKRHRIRRFDAPPCARYIAPAAAQGRRRNDRIRQRPRHYAHCPHPPRQPAAQTGASSAGWPDRQPHRNRAGGAGAEEAA
What are the official names of this protein?
Putative transposase y4uE.
What is the protein family that this protein belongs to?
Belongs to the transposase 9 family.
Protein: RL22_STREM
Sequence: MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTPNKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.