PharMolix/UniProtQA huggingface dataset:
Protein: CD22_MOUSE
Sequence: MRVHYLWLLLILGHVASARYSSANDWTVDHPQTLFAWEGACIRIPCKYKTPLPKARLDNILLFQNYEFDKATKKFTGTVLYNATKTEKDPESELYLSKQGRVTFLGNRIDNCTLKIHPIRANDSGNLGLRMTAGTERWMEPIHLNVSEKPFQPYIQMPSEIRESQSVTLTCGLNFSCFGYDILLKWFLEDSEITSITSSVTSITSSVTSSIKNVYTESKLTFQPKWTDHGKSVKCQVQHSSKVLSERTVRLDVKYTPKLEIKVNPTEVEKNNSVTMTCRVNSSNPKLRTVAVSWFKDGRPLEDQELEQEQQMSKLILHSVTKDMRGKYRCQASNDIGPGESEEVELTVHYAPEPSRVHIYPSPAEEGQSVELICESLASPSATNYTWYHNRKPIPGDTQEKLRIPKVSPWHAGNYSCLAENRLGHGKIDQEAKLDVHYAPKAVTTVIQSFTPILEGDSVTLVCRYNSSNPDVTSYRWNPQGSGSVLKPGVLRIQKVTWDSMPVSCAACNHKCSWALPVILNVHYAPRDVKVLKVSPASEIRAGQRVLLQCDFAESNPAEVRFFWKKNGSLVQEGRYLSFGSVSPEDSGNYNCMVNNSIGETLSQAWNLQVLYAPRRLRVSISPGDHVMEGKKATLSCESDANPPISQYTWFDSSGQDLHSSGQKLRLEPLEVQHTGSYRCKGTNGIGTGESPPSTLTVYYSPETIGKRVALGLGFCLTICILAIWGMKIQKKWKQNRSQQGLQENSSGQSFFVRNKKARRTPLSEGPQSQGCYNPAMDDTVSYAILRFPESDTHNTGDAGTPATQAPPPNNSDSVTYSVIQKRPMGDYENVNPSCPEDESIHYSELVQFGAGKRPQAKEDVDYVTLKH
What is the function of this protein?
Mediates B-cell B-cell interactions.  May be involved in the localization of B-cells in lymphoid tissues.  Binds sialylated glycoproteins; one of which is CD45.  Preferentially binds to alpha-2,6-linked sialic acid.  The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface.  Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling.  Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
What are the official names of this protein?
B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM, Sialic acid-binding Ig-like lectin 2, Siglec-2, T-cell surface antigen Leu-14.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CAH10_MOUSE
Sequence: MEIVWEVLFLLQANFIVCISAQQNSPKIHEGWWAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGRKVSGTMYNTGRHVSLRLDKEHLVNISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRITYKNDAYLLQGLNIEELYPETSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSLRLLSQNQPSQIFLSMSDNFRPVQPLNNRCIRTNINFSLQGKDCPNNRAQKLQYRVNEWLLK
What is the function of this protein?
Does not have a catalytic activity.
What are the official names of this protein?
Carbonic anhydrase-related protein 10, Carbonic anhydrase-related protein X, CA-RP X, CARP X.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
Protein: AROC_LISMF
Sequence: MRYLTAGESHGPGLTTIIEGLPAGMPLLAEDVNKELKRRQGGHGRGARMRIEKDQVQITAGIRHGKTLGAPVAMFVENKDWKHWETVMSIEPVPEKNEKSRRVSRPRPGHADLVGGMKYGHNDMRNVLERSSARETTVRVAAGAVAKKLLHELGIEVAGHVLEIGGTRANLTRDYAVSEIQETSEASPVRCLDGVAAEEMMQKIDDAKKNGDTIGGIVEVVVGGVPAGLGSYVQWDKKLDAKIARAIVSINAFKGAEFGVGFEAARKPGSEVMDEILWSKEDGYTRRTNNLGGFEGGMTNGMPIVVRGVMKPIPTLYKPLQSVDIDSKETFNASVERSDSCAVPAASVVAEAVVAWEVAVAVLEKFDGDRFDTLKKHVEEHRNLTKEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: GPDA_RUEPO
Sequence: MSIAVLGSGAFGTALAISLAGKGPVTLWSRAPEQARQMQETRENHQRLPGLPLPAALNVTADLDQATRCDTLLLAVPMQKLRGMLSEHAAALHGRVLVACCKGIELNSGLGPMAVMAETLPGTRTALLTGPSFAQDIARGLPTALTLACADPDLGRDLQAQLTTTNLRLYRTTDTIGAELGGALKNVIAIGCGACIGAGMGDSARAALLTRGFAEMQRLAALKGARPETLMGLSGLGDLMLTCSSDLSRNYRFGLALGRQEPFDRATTVEGVATAHAVAQLARDLGIDMPISTTVAQLSNGDYSVAEAMRSLLNRPLKEE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPO11_YEAST
Sequence: MALEGLRKKYKTRQELVKALTPKRRSIHLNSNGHSNGTPCSNADVLAHIKHFLSLAANSLEQHQQPISIVFQNKKKKGDTSSPDIHTTLDFPLNGPHLCTHQFKLKRCAILLNLLKVVMEKLPLGKNTTVRDIFYSNVELFQRQANVVQWLDVIRFNFKLSPRKSLNIIPAQKGLVYSPFPIDIYDNILTCENEPKMQKQTIFPGKPCLIPFFQDDAVIKLGTTSMCNIVIVEKEAVFTKLVNNYHKLSTNTMLITGKGFPDFLTRLFLKKLEQYCSKLISDCSIFTDADPYGISIALNYTHSNERNAYICTMANYKGIRITQVLAQNNEVHNKSIQLLSLNQRDYSLAKNLIASLTANSWDIATSPLKNVIIECQREIFFQKKAEMNEIDARIFEYK
What is the function of this protein?
Required for meiotic recombination.  Mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination.  The action of SPO11 is important in setting off a regulatory chain of events encompassing 5' to 3' resection.  When there are no SPO11-DSBs, resection of a site specific VDE-DSB takes place but it is faster than in wild-type meiosis and increases the risk of uncovering flanking homology.
What are the official names of this protein?
Meiosis-specific protein SPO11, Sporulation-specific protein 11.
What is the protein family that this protein belongs to?
Belongs to the TOP6A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: G3PA_CHOCR
Sequence: MAFVAPVATVRATTKSSVCQVQGRSTFAQFSGMKKVNQSSRLQPAQSGSAFGGYSDANDAFYTRVSGIVAATFGPTMKVRVAINGFGRIGRNFIRCWAGRSDSNMEVVCINDTSGVKTASHLLKYDSILGTFDADVSAGEDTISVNGKTIKIVSNRNPLQLPWKEMNIDIVVEATGVFVDAPGAGKHIEAGAKKVLITAPGKGDGIGTFVVGVNEKDYSHDKYDIVSNASCTTNCMAPFMKVLDDEFGVVRGMMTTTHSYTGDQRLLDAGHRDLRRARSAALNIVPTTTGAAKAVALVVPSLKGKLNGIALRVPTPNVSVCDVVMQVNKKTFKEEVNGALLKASEGAMKGIIKYSDEPLVSCDHRGTDESTIIDSSLTMVMGDDMIKVVAWYDNEWGYSQRVVDLGEVMARQWK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, chloroplastic, NADP-dependent glyceraldehydephosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCH1_SULTO
Sequence: MEETLNQEKMVEEIAKRIREILEILGENPDREGLRETPLRVARALLEMTSGLRTPQPQIKTFNLSEDGISEVEDQIILVKNIGFSSLCEHHLLPIIGKVHVAYIVGQERKVAGFSKIIRIVNYYASRPQIQERLVQQIADAIMNSDIHPKGVMVIGDALHMCAYVRGVKDREASLLSVATRGLFKNNVSLRNYVFRLLETSKKTSLL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: VATF_METM6
Sequence: MRIGVVGDPDVVVGFRLAGLTDVYEVKSPEQAAKAIEELNNNSEIGLIITTERIGEQIRDSISGVKKIVVEVPDKNGPIVRENDPVKVLVRNAVGVDIK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: RPOA_MAGMM
Sequence: MYRNWTELIKPHTIELGGDETEIQRKATLVAEPLERGFGTTLGNALRRVLLSSLQGAAVSTVRIEGVLHEFSSVPGVIEDVTDIILNIKGLALRMESTGIKNIYLRVDKEGPVTAGMIECETGIEILNPDHHIATLNKSGTLDITMTVTTGKGYVRAQLNREDESYAIGDIPIDASYNPVKKVAYRVENARVGQQTDYDKLIMDIETNGVVTPEDALALAAKILQDQLNPFINFDDVPTAHDHEMEDRPQWNPNLFRKVDELELSVRSANCLKNDDIVYIGDLVQKSESEMLKTPNFGRKSLNEIKEVLDEMGLSLGMTLDTWPPENIDDLSKQFEEENF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SK1_GYNLU
Sequence: EQFEDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, GynLu-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCP_SULIY
Sequence: MTVLLFGFEPFLEYKENPSQLIAEALNGSTILKEEVKGVILPVEYEKIEDLIVTKIREMKPILTLGIGVAPGRAKITPEKIAINYKYSREGDNAGKKYKGEKIDPLGQDGIFTNIPVEDLVDLLNENGIPAELSLSAGSYLCNNAMYIIIREARKYNSLGGFIHVPLHESYAARIQRPIPSMSLDTMIRGIRLSMEFILTNKKENLTFS
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNU3_YEAST
Sequence: MEPFDFFNSFKHALAVLKLPSKSMSTTDLKAFGERFAKSHTKFPAAPAMTKSILPNFSTVFLTAFSTCSKLRTSTFAIAKTASLSFANCEIPFAACSVLSWSLPTIAALQPRRTKASVCTRHIVPAPPVTNATLPLNKSGLQEPSVTNLPSKVFAVFIVSMTRTYDLPNSKSVNIRNYELLFKFRFSLIWSLTLIPILFGKLQ
What are the official names of this protein?
Putative uncharacterized protein YNL203C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS9_STAEQ
Sequence: MAQVEYKGTGRRKNSVARVRLVPGEGNITVNERDVRDYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKKARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS6_THET2
Sequence: MRRYEVNIVLNPNLDQSQLALEKEIIQRALENYGARVEKVEELGLRRLAYPIAKDPQGYFLWYQVEMPEDRVNDLARELRIRDNVRRVMVVKSQEPFLANA
What is the function of this protein?
Located on the outer edge of the platform on the body of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MURI_SHEB9
Sequence: MSRPILVFDSGIGGLSVLAEIRKSLPHSDYCYLFDNARLPYGELEEQVLIAGCVALVCDLVARTNAMIVVVACNTASTVVLPALRANLSIPVVGVVPAIKPAAQMSKSKRIGLLATPGTVKRHYTHELISQFADDCHVELFGCSELVMMAEQKIATGEMDMHRLADLLAPVVAAQLDVLVLGCTHFPMIQAELQQVLGAGVTLMDSGAAIAKRVVTLLTQQNLIVEQRRVTNEREALGQSVMQAFYTKAEISEGLTTTLIDCGFSTIERITTTN
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: GAL7_STRLI
Sequence: MKKTSTRLADGRELVYYDLRDDTVRDAVDRRPLERTVTTSEVRRDPLLGDSAPSRLAPQGRTYHPPADQCPLCPSGRGTAERDPAYDVVVFENRFPSLAGDSGRCEVVCFTSDHDASFADLSEEQARLVVDAWTDRTSELSHLPSVEQVFCFENRGAEIGVTLGHPHGQIYAYPFTTPRTALMLRSLAAHKDATGGGNLFDSVLEEELAGERVVLEGEHWAAFVAYGAHWPYEVHLYPKRRVPDLLGLDEAARTEFPKVYLELLRRFDRIFGEGEPPTPYIAAWHQAPFGQLEFEGVTRDDFALHLNFSLPPYVRQAEVPRGLRIRHERVHQRDVPPERAAERLREVADVHERE
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: Y1276_LACGA
Sequence: MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKSGGPDPSGNPTLRMVMDKARAANMPKTNIERAIKKAEGNSDEHYDEITYEGYAPGGVAVLVEALTDNKNRTASDVRVAFTRNGGSLGATGSVAYMFDRKGYIVIDRSTTDADEDQVLLDVMDAGGDDLETSDDAFEIYTDPKQFTAVRDALEKAGYKLANAELTMIPQNTTPVPADKKEQFTHLIDALEDNDDVSNVYTAAADDDE
What are the official names of this protein?
Probable transcriptional regulatory protein LGAS_1276.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR2_ARATH
Sequence: MAEIKDEGSAKGYAFPLRNPNVTLNERNFAAFTHRSAAAHPWHDLEIGPEAPTVFNCVVEISKGGKVKYELDKNSGLIKVDRVLYSSIVYPHNYGFIPRTICEDSDPMDVLVLMQEPVLTGSFLRARAIGLMPMIDQGEKDDKIIAVCADDPEFRHYRDIKELPPHRLAEIRRFFEDYKKNENKKVDVEAFLPAQAAIDAIKDSMDLYAAYIKAGLQR
What are the official names of this protein?
Soluble inorganic pyrophosphatase 2, Pyrophosphate phospho-hydrolase 2, PPase 2.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKR1_ORYSI
Sequence: MAAAAMATVAVPRVKLGSQGMEVSAQGLGCMGMCPAFEPPKPEADMVALIRHAIAAGVTFFDTSDLYGPHTNEVLLGKALQGGGVRDRVELATKFGKFFAGGKPGIRGDPAYVRAACEGSLRRLGVDCIDLYYQHRVDKKVPIEVTIGELKKLVEEGKIRYIGLCEASASTIRRAHAVHPITAVQLEWSLWSRDVEEDIVPTCRELGIGIVAYSPLGKGFFSSGAKLVDSLPDHDFRKLIPRFQPGNIEKNAEIFERVNEMAARKGCTPSQLALAWIHHQGRDVCPIPGTTKIENFNQNVAALSVKLTPAEMAELESYASNVHGDRYPLMMANTTWQDSETPPLSSWKSE
What are the official names of this protein?
Probable aldo-keto reductase 1.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: RUVB_COREF
Sequence: MERTEFEIPGGIPPRRHGGTGRDPDTSVDANIQPDDVEAEVTLRPRSLDEFIGQPKVRDQLSLVLTGAKKRGVVPDHVLLSGPPGLGKTTMAMIIAQELGTSLRMTSGPALERAGDLAAMLSNLMEGDVLFIDEIHRIARPAEEMLYMAMEDFRIDVIVGKGPGATSIPLEIPPFTLVGATTRSGMLTGPLRDRFGFTAQMEFYDVADLTRVVKRTARILEVGIDADAAVEIASRSRGTPRIANRLLRRVRDFAEVHADGHITLGAANAALIVFDVDELGLDRLDRAVLDALVRGHGGGPVGVNTLAVAVGEEPATVEEVCEPYLVRAGMIARTGRGRVATAAAWRHLGLEPPEGTIGDY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SARU_STAA8
Sequence: MDYQTFEKVNKFINVEAYIFFLTQELKQQYKLSLKELLILAYFYYKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRKKIACVINELDKIIKGFNKERDYIKYQWAPKYSKEFFILFMNIMYSKDFLKYRFNLTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLNNKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF
What is the function of this protein?
Positive regulator of RNAII and RNAIII in a cell density-dependent manner.  It can contribute to the expression of virulence genes controlled by agr.  May also regulate target genes via an agr-independent pathway.
What are the official names of this protein?
HTH-type transcriptional regulator SarU, Staphylococcal accessory regulator U.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_PARPJ
Sequence: MRLILLGAPGAGKGTQANFIKEKFGIPQISTGDMLRAAVKAGTPLGLEAKRFMDAGELVTDELIINLVKERLQQPDCANGYLFDGFPRTIPQAEAMKQAGVPIDYVLEIDVPFDEIILRMSGRRSHAASGRTYHVKFNPPKVEGVDDMTGEPLIQRDDDKEETVKKRLEVYEAQTKPLIEYYNTWAKNGDSSTPLTAPQYRRISGLGSVDEIRDRAFEALK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCP35_ARATH
Sequence: MKKNALWLLCILVLPAIACGRKPEKKVTISSSGRKEDDLVTGLPGQPPVNFKHYAGYVNLGPEQKQKALFYWFFEAQQNSSRRPLVLWLNGGPGCSSIAYGAAQELGPFLVHDNGGKLTYNHFSWNKEANMLFLEAPVGVGFSYTNNSMDLQKLGDEVTASDSLAFLINWFMKFPEFRSSEFYISGESYAGHYVPQLAEVIYDRNKKVTKDSSINLKGFMIGNAVINEATDMAGLVDYAWSHAIISDEVHTSIHGSCSFEEDTTNKTEQCYNNFKGFMDAYNDIDIYSIYTPVCLSSLLSSSPRKPKIVVSPRLLTFDDLWDKFPAGYDPCTESYAENYFNRKDVQVALHANVTNLPYPYSPCSGVIKRWSDAPSTMIPIIQKLLTGGLRIWIYSGDTDGRVPVTSTRYSIKKMGLKVESPWRSWFHKSQVAGWVETYAGGLNFVTVRGAGHQVPALAPAQSLTLFSHFISSVPLPSKRF
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 35.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNS1_DANRE
Sequence: MILEHRKQEERREDHSKRVVKERQLEANLSCEDRIERKRLLRKLQDEEYGKQIEESLLRAEEDKLFRERQLEQEERMAKELARINNEKLRDEKMRQYIKENSVELRELELKLKSAYLNRERAAQMAEKEAMRYETLREEAMIARTMRDEHELAEMEKEKLEQKKYEEVVRYQQELERQLEEKERKRQEAYEEFLKEKHMVDEIVRKIYMEDQMELQLQLDKMKATQRYIEDFKKQQAEWRRMEREKVEAENRRIIEFAQYQQRKEEDRMAKVREREQAKETLHKMLSEQIELEKQQREKMERAREELCLEEQAEAARQQEIEEMEKRIRQRLELQQTQQEMMAFKKLRLQEEKEEEEAFRQMMMAKFAEDDRIEQMNAQKRRMKQLEHKRAVEQLLEERRQQYLAEQEREEQERAVELEREAQRRKIIEEERQRLLKQHATKLLGYLPKGIFKEEDLEHFDEDFKSNFKQRQADIFSDEGWGDDSQ
What is the function of this protein?
May play a role in the control of meiotic division and germ cell differentiation through regulation of pairing and recombination during meiosis (By similarity).  Required for sperm flagella assembly (By similarity).  May play a role in the assembly and function of the outer dynein arm-docking complex (ODA-DC).  ODA-DC mediates outer dynein arms (ODA) binding onto the axonemal doublet microtubules (By similarity).
What are the official names of this protein?
Meiosis-specific nuclear structural protein 1.
What is the protein family that this protein belongs to?
Belongs to the MNS1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme. Note=Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme.
Protein: ALS3_CANAL
Sequence: MLQQYTLLLIYLSVATAKTITGVFNSFNSLTWSNAATYNYKGPGTPTWNAVLGWSLDGTSASPGDTFTLNMPCVFKFTTSQTSVDLTAHGVKYATCQFQAGEEFMTFSTLTCTVSNTLTPSIKALGTVTLPLAFNVGGTGSSVDLEDSKCFTAGTNTVTFNDGGKKISINVDFERSNVDPKGYLTDSRVIPSLNKVSTLFVAPQCANGYTSGTMGFANTYGDVQIDCSNIHVGITKGLNDWNYPVSSESFSYTKTCSSNGIFITYKNVPAGYRPFVDAYISATDVNSYTLSYANEYTCAGGYWQRAPFTLRWTGYRNSDAGSNGIVIVATTRTVTDSTTAVTTLPFDPNRDKTKTIEILKPIPTTTITTSYVGVTTSYSTKTAPIGETATVIVDIPYHTTTTVTSKWTGTITSTTTHTNPTDSIDTVIVQVPSPNPTVTTTEYWSQSFATTTTITGPPGNTDTVLIREPPNHTVTTTEYWSESYTTTSTFTAPPGGTDSVIIKEPPNPTVTTTEYWSESYTTTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSYTTTTTVIAPPGGTDSVIIREPPNPTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSYTTTTTVIAPPGGTDSVIIKEPPNPTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSYATTTTITAPPGETDTVLIREPPNHTVTTTEYWSQSFATTTTVTAPPGGTDTVIIREPPNHTVTTTEYWSQSFATTTTIIAPPGETDTVLIREPPNPTVTTTEYWSQSYTTATTVTAPPGGTDTVIIYDTMSSSEISSFSRPHYTNHTTLWSTTWVIETKTITETSCEGDKGCSWVSVSTRIVTIPNNIETPMVTNTVDTTTTESTLQSPSGIFSESGVSVETESSTFTTAQTNPSVPTTESEVVFTTKGNNGNGPYESPSTNVKSSMDENSEFTTSTAASTSTDIENETIATTGSVEASSPIISSSADETTTVTTTAESTSVIEQQTNNNGGGNAPSATSTSSPSTTTTANSDSVITSTTSTNQSQSQSNSDTQQTTLSQQMTSSLVSLHMLTTFDGSGSVIQHSTWLCGLITLLSLFI
What is the function of this protein?
Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation.  Plays an important role in the biofilm formation and pathogenesis of C. albicans infections.  Necessary for C. albicans to bind to N-cadherin on endothelial cells and E-cadherin on oral epithelial cells and subsequent endocytosis by these cells.  During disseminated infection, mediates initial trafficking to the brain and renal cortex and contributes to fungal persistence in the kidneys.
What are the official names of this protein?
Agglutinin-like protein 3, 3D9 antigen, Adhesin 3.
What is the protein family that this protein belongs to?
Belongs to the ALS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Note=Covers the surface of the germ tube.
Protein: Y890_MYCTO
Sequence: MRALLAQNRLVTLCGTGGVGKTRLAIQIASASELRDGLCFVDLAPITESGIVAATAARAVGLPDQPGRSTMDSLRRFIGNRRMLMVLDNCEHLLDACAALVVELLGACPELTILATSREPIGMAGEITWRVPSMSITDEAVELFADRASRVQPGFTIANHNAAAVGEICRRLDGIPLAIEFAAARVRSMSPLEIADGLDDCFRLLAGGVRGAVQRQQTLRASIDWSHALLTETEQILFRRLAPFVGGFDLAAVRAVAAGSDLDPFSVLDQLTLLVDKSLVVADDCQGRTRYRLLETVRRYALEKLGDSGEADVHARHRDYYTALAASLNTPADNDHQRLVARAETEIDNLRAAFAWSRENGHITEALQLASSLQPIWFGRAHLREGLSWFNSILEDQRFHRLAVSTAVRARALADKAMLSTWLATSPVGATDIIAPAQQALAMAREVGDPAALVRALTACGCSSGYNAEAAAPYFAEATDLARAIDDKWTLCQILYWRGVGTCISGDPNALRAAAEECRDLADTIGDRFVSRHCSLWLSLAQMWAGNLTEALELSREITAEAEASNDVPTKVLGLYTQAQVLAYCGASAAHAIAGACIAAATELGGVYQGIGYAAMTYAALAAGDVTAALEASDAARPILRAQPDQVTMHQVLMAQLALAGGDAIAARQFANDAVDATNGWHRMVALTIRARVATARGEPELARDDAHAALACGAELHIYQGMPDAMELLAGLAGEVGSHSEGVRLLGAAAALRQQTRQVRFKIWDAGYQASVTALREAMGDEDFDRAWAEGAALSTDEAIAYAQRGRGERKRPARGWGSLTPTERDVVRLVSEGLSNKDIAKRLFVSPRTVQTHLTHVYAKLGLASRVQLVDEAARRGSPS
What are the official names of this protein?
Putative HTH-type transcriptional regulator MT0914.
Protein: TRPA_THEFY
Sequence: MTVLRRKLAEAKAEGRAALVGYYPAGFPDVASSIRVVQAMVAGGCDVIEVGFPYSDPTMDGPVIQQAADRALAAGTTPKDVLAVVRAVADAGAAALVMSYWNPIEKYGVDAFAADLAAAGGSGLITPDLIPEEAEPWIKASDAAGIDRIFLVAPSSTDERLAKTCAASRGFVYAASLMGVTGTRDKVAATARRLVERTRAVTRDSGLPICVGLGISNGAQAAEVASYADGVIVGTGFCQRVLDAPDVDTACQQVRDFAAELAAGVRAAAR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: DNAJ_GLOVI
Sequence: MARDLYETLNVSRDASKEDIKRAYRKLARQYHPDVNKDAGAEDTFKELSRAYEVLSDDDQRARYDRFGEAGLNGGVGGGPGDFAGAAGFGDISDIFESFFGGFAGAGTGGRRATRPGGPTRGDDLRYDMVLEFQEAIFGGEKEITINHLITCETCRGSGSKPGSGPMTCRNCGGQGQIRQARRTPFGLFTQVAACPNCQGTGEVIESPCPTCSGRGRNQKQTTIKITIPAGVDAGSRLRVQGEGDAGMRGGPPGDLFIYVSVRNHPVFRREGQDIYSIAEISYLQAILGSQMSVETVDGPQTVVVPPGTQPETVLTLDGKGVPRIGNPTRRGNHYLQLKVVIPTKLGAEERELLTKLAKARGEKVSKKEGLEGLIDSIGNLFH
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.