PharMolix/UniProtQA huggingface dataset:
Protein: LPXC_LEPBJ
Sequence: MKEILYRKSIQDRVRIKGIGLHSGKEVNLTAHPAPSGTGIVFEYRKGLEKASISVELSNVVDTSNATTLGDGLHKIQTVEHLLAAIYALGLTDLILEIDAVEVPIMDGSSLPFLQALESAGIVKYPEIIEPIYVQNPLWVVDGDKYLVLLPSDELKVTYTIDFNHPLLKGQNITISLDKETIKQEILPARTFGFLKDVEALQAKGLAMGGSLDNAIVLTQDGYLNQQLRFENECVRHKILDLFGDISIAGRPIIGHYLASKAGHALDISMAKLVMSSVTGDEISKYKSRRIPLFKRKVAVV
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RL32_BRAHW
Sequence: MAVPKHRKSKAKKRSRQAANDKRFLGSLSICPQCGAERMPHRICPECGFYKDRVIKAPKTQNAG
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: EDNRA_RAT
Sequence: MGVLCFLASFWLALVGGAIADNAERYSANLSSHVEDFTPFPGTEFNFLGTTLQPPNLALPSNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGEQHRTCMLNATTKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTSVPMNGTSIQWKNQEQNHNTERSSHKDSMN
What is the function of this protein?
Receptor for endothelin-1.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
What are the official names of this protein?
Endothelin-1 receptor, Endothelin receptor type A, ET-A, ET-AR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE1_MYCA9
Sequence: MTRLTREHYAKLYGPTTGDRIRLADTDLIIEITEDRCGGPGLAGEEAVFGGGKVLRESMGQSRLTRAGGAPDTVITGAIIIDHWGIIKADIGIRDGRIVGIGKAGNPDIMDGVDPALIVGPSTEIIAGNNRIVTAGGIDCHVHFICPQILPEALSGGITTMIGGGTGPAEGSKATTVTPGAWHLGRMLQALDGWPMNILMLGKGNTVNPDAMWEQLRGGAAGFKLHEDWGTTPAVIDACLRVADEADVQVALHSDTLNETGFVEGTLAAIGGRAIHAYHTEGAGGGHAPDIITVASHPNVMPSSTNPTRPHTVNTLDEHLDMLMVCHHLNAAVPEDLAFAESRIRPSTIAAEDLLHDIGAISMIGSDSQAMGRIGEVVMRTWQTAHVMKKRRGALPGDPSGPNGNDNNRVRRYVAKYTICPAITHGIDHEIGSVEVGKLADLVLWEPAFFGVRPHAVIKGGGIVWAAMGDANASIPTPQPVFPRPMFSAMHAVAAGLAVHFVSPTAIEDDLAARLALRRRLVPTRDVRNRGKADLPLNDAMPDIRVDPDTFTVRIDGEVWEEHPAAELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFNA_METBU
Sequence: MEENGKTKEEILLFLKKAKSADASYERVLSSMCTYPHEIAVLAHTQFIESNMGDPGLFPGTFNLEKQVLAMFGKMLHHKNSPEKAGYLTTGGTESNIQAIRSMHNFRHDISRPNIVMPESAHFSFDKVANLSGIEIRKASLDKLLKVDLDSVRSLIDKNTIGLVGIAGTTEFGQLDPINELSKIAIEKGIFLHIDAAFGGFVIPFMDIDYTYDFRLEGVTSMTIDPHKMALSTIPSGGLLFKEPEYFECLEIHTPYLSVNKQYSLTGTRSGAGVASTYAVMKHLGRKGYKKVVSDCMSVTKKLVDGAEKLGINTVIDPVLNIVALDVPEADLVRKKLLDEYGWHVSITRNPRALRIVIMPHIKNETIELFLKDLAKVIK
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: DTXS2_METRA
Sequence: MLRIPGKSLGYHEDISLTPWQAILASVIVLLGLKVATILYTAFYNVFLHPLRRFPGPVTWIAAPWMKSISHIRGQQDHQIVKLHQKLGHIIRVGPDTLSFTEMSAWRDIYGTGHAELPKHIYKGSGMEERPNIITAHSRDHHRFRKAMTPALTPEAITHEEALIKGYVDMLIEHLHKFAKSSDPYVNVSQWYTMTTFDIFGDLCYGESFNSLATGKQHLWLKSMSSMKVLVPLLVFPYISWLLVWWLLSPEQQRSLSDHQKRSYELTMKRIANRDTHPRHDFMTFMLRNRGEDQGVTDHELASNSDIVISAGSETTSTALTGITFFLCSNPDAMARCAKEVREAFKSDDEITFKATAELPFMLACIEETLRMYPPVPTSLIRRTLPGRPTLIAGELIPENTIVGVHHLATYRSERNFFDAKAFRPERWLAETRNDPKSPFKDDRLDAVRPFSYGPRNCIGRNLAYHEMRLILAKLLWHFDLKLKPGYEDWGFKQRTFQLWEKPKLVVEFKERQFQV
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of destruxins, insecticidal cyclic hexadepsipeptides which induce flaccid paralysis and visceral muscle contraction in insects through targeting the calcium channels and vacuolar-type ATPases (PubMed:22232661).  The aldo-keto reductase dtxS3 converts alpha-ketoisocaproic acid from deaminated leucine into alpha-hydroxyisocaproic acid (HIC), which is the first substrate for destruxin assembly by dtxS1 (PubMed:22232661).  L-aspartate decarboxylase dtxS4 converts aspartic acid into beta-alanine, the last substrate for the destruxin assembly line performed by dtxS1 (PubMed:22232661).  The nonribosomal peptide synthetase dtxS1 synthesizes destruxins B and B2, whereas the cytochrome P450 monooxygenase dtxS2 is required to convert destruxin B into other destruxin derivatives, including destructins C, D, A and E (PubMed:22232661).  Destruxin E-diol (ED) is further produced in a non-enzymatic manner from destruxin E (PubMed:22232661).  Destruxins play an important role in virulence and escape from insect host immune defenses (PubMed:22232661).
What are the official names of this protein?
Cytochrome P450 monooxygenase dtxS2, Destruxin synthesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MAO1_PSEAE
Sequence: MTETAKRPLYVPHAGPSLLEMPLLNKGSAFSTQERIDFNLQGLLPHNIETIEEQTERAYSQYNLCNTDLDRHIFLRSIQDNNETLFFRLLEEHLEEMMPIIYTPTVGQACQEFSKIYRTHRGLFISYPDRERIDDILRSATKNNVKIVVVTDSERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPDLLNDPMYMGWRHERVSGAQYEEFVDLFIQAIKRRWPNVLLQFEDFAQTNAMPLLERYKDELCCFNDDIQGTAAVAVGTLLAACKAKGEKLSEQTVTFVGAGSAGCGIAEQIIAAMQLEGLDEAQARRRIFMVDRWGLLTDDMSNLLDFQHRLAQKRADLGAWGGQQGDDLALLEVIRNARPTVLIGVSGQRGLFSEEVIRELHSHCKQPLVMPLSNPTSRVEATPQEILNWTDGQALVATGSPFQPVQVGDKRIPIAQCNNAYIFPGIGLGVIAARANRVTEGMLMAAANALANCSPIVTQGEGAVLPALGDIREVSKRIAVAVAKQAQAEGKALHTSDEVLNDAIEANFWFPRYRAYRRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: RR11_CHLRE
Sequence: MAKQTRKLTTNKTKKKIFRGVVHIQAGHHNTIVTITNIRGEVLCWSSAGACGFRGKRKSTSFAAKKAAETVARKSRDFTMKAAKILVTGPGQGRESAIREIFKAGIKVSVIREKTGIPHNGCRPPKKRSV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1792_ARCFU
Sequence: MLCISNIMLEKPNKGGIMRYGKIGVATAMAVGAAVGYAVESGKWFITVIAVLAGVALLSLVKRRVDEVVEDERTVRVGERASRRTVEIFSIGAALSGAVMLALDLHTEAALALEFAVCCVLVLYLIFYGYYSFRALD
What are the official names of this protein?
Uncharacterized protein AF_1792.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URK_YERE8
Sequence: MTDKAHQCVIIGIAGASASGKSLIASTLYRELREQVGDQHIGVIPEDGYYKDQSHLSMEERVKTNYDHPSAMDHNLLLEHLQSLKAGKPIELPLYSYTEHTRKKETVHLEPKKVIILEGILLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_DESAP
Sequence: MALRFILGRAGTGKTRLCLEEIRKELRQAPDGPPLVFLVPEQATFQTEYALALTPGLSGMFRAQVLSFRRLAWRVFSEVGGAARPHVGDVGKRMMLARILARRRNELRLFGRAAGQYGFSGTLAGVLSELKTYLVTPEALEQAVRMLPGTAETDSLQAKLEDLRLLYTDFERELAGKYIDPDDYLTLLAARLGESPTLRAAEVWVDGFAGFTPQEYAVLEALLKAAARVNVALCLDPRSGRREDLELFQVTRDTRARLAELARKNGVELERPVELAGPPARFRANPALAHLEREFFRRPTKKFAGPPENLRLVAAASRRAEVEGAAREILRLSRERGWRWRDVSLVVRNLADYHELVATVFADYGIPCFIDRKRPVRHHPLVELIRSALETVTENWTYDPVFRYLKTDLVPVSRGDVDLLENYVLAHGIKGAKWADPEDWHYRRSDALNRPVPNGTGAPAPSDRDRYLREKVNRIRRRAARHLLDFQRRVQAAGTVRELTAALYDLLSDLDVPGRIEEWSREAETEGRLEAAREHRQLWDGVVELLDQVVETLGDEALTPEEYGRILDSGMDGLQLALIPPALDQVLVGSLERSRNPDIRAAFVLGVSEGVLPGRHGGTGLFTDREREVLLAAGLEVAPDTRRKVYEEQYLVYIALTRAGHYLWVSYPLADEEGGALAPSSVIPRLRELFPGLREETLALEPEGTAPGADLPYVTAPGRTLGFLVTRLRDWKSGVTVDPVWWSVFNWFAAHAGWRERCAPVLAGLFYENREPRLDPELTPELYGSRLVVSVSRLEEFRGCPFAHFARYALRLKERDVCRLAAPDIGLFFHAALKTFEDRLREAGMEWDALESADCTRLASAVVEELAPQLQSEVLLSSPRLRFLTGKLERVVERTAGVMAAHARHSRFQPVAVEVAFGPGRDVPGPAYPLPGGGSVELAGRIDRVDVAHTDNAAYLRVIDYKAGPRSLALDDVYYGLNLQLLVYLEAGLREAAALAGRECRPAGAFYFRVQNPLLKGGTPVPPAEVAPRLLKAFRLQGLVLDDPALLRLMDDAIGSESAIVPAGLKQDGTVKKKPGVVSAAQLERLQEHVRRVVAETAAEIQAGVVAIAPYRKGQANACRYCAFKPVCAFDPLLESNRYRQLRALTAGELWRLLGLPEEDEPGDE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: CMOB_YERPE
Sequence: MIEFGDFYRLIAKGPLSPWLDTLPAQLSAWQRESLHGKFKTWFNAVEHLPQLTPTTLDLHSGVRAEMSPPISAGQREGMENMLRALMPWRKGPFSLYGLDIDTEWRSDWKWQRVLPHISPLAGRTILDVGCGSGYHLWRMIGEGAHLAVGIDPMQLFLCQFEAIRKLLGGDQRAHVLPLGIEQLPELAAFDTVFSMGVLYHRRSPLDHLYQLKNQLVTDGELVLETLVVEGDSQQVLVPGDRYAQMRNVYFIPSAPALKAWLEKCGFVDVRIADMAVTTTEEQRRTDWMTSESLAEFLDPHDHSKTVEGYPAPLRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RL23_BURO1
Sequence: MSEIRKNDHRLMQVLLAPVISEKATLVADKNEQVVFEVAPDATKQEVKAAVELLFKVEVDSVNVLVQKGKQKRFGRSMGRRKDVKKAYVCLKPGQEINFEAEAK
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RR19_EUGGR
Sequence: MSRSLKKGPFVFYSLIKKVDQMNSNRFKSVILTWSRSCTIIPIMIGNTIGVYNGKEHIPVLVSDQMIGHKLGEFVQTRNYRGHKKHDKKTKTKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YQGF_NITEU
Sequence: MPDMTSASSGTVLAFDFGKRRIGVAIGEHELRMAHPLTTIDQSMTRPRFEKIAELIEAWQPVLLVVGLSVHADGTEHEITRLCRRFARRLEGRFRIPVALADERYTTVIARSVLEEVGVTGKKQRPMLDQIAAQHILQTYFDLSHAAS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_ANASK
Sequence: MDPAFHEALASGIEALGLPVDEAARALLERYADRLLAWNRKVNLTAITAPAELAEKHLVDSLVLLPVLSGARTLLDVGSGAGLPGMPLACARRDLSVTCCDGVAKKIAFVKAVSAELDLPVRGVAVRAEGDPEREGLPRADAVVSRALADPDRWVPVGARYLAEGGTLLAMLGREVDRAALEAVGAAEGLTLVGLDVYELPISRAARAVARWQRR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_YEAST
Sequence: MPSRFTKTRKHRGHVSAGKGRIGKHRKHPGGRGMAGGQHHHRINMDKYHPGYFGKVGMRYFHKQQAHFWKPVLNLDKLWTLIPEDKRDQYLKSASKETAPVIDTLAAGYGKILGKGRIPNVPVIVKARFVSKLAEEKIRAAGGVVELIA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L28, L27a, L29, Large ribosomal subunit protein uL15, RP44, RP62, YL24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QEDH_PSEPU
Sequence: MTIRSLPAALSPLSMAVQAVLLVSSLALAPAANAKPVTWEDIANDHLNTQNVLQYGMGTNAQRWSPLAMVNDKNVFKLTPAWSYSFGDERQRGQESQAIINDGVIYVTGSYSRVFALDAKTGRRLWTYNHRLPDNIRPCCDVVNRGAAIFGDKIYFGTLDARVIALNKDTGKVVWNKKFGDHSAGYTMTGAPTLIKDQKSGKVLLIHGSSGDEFGVVGQLYARDPETGEEVWMRPFVEGHMGRLNGKDSTPTGDVKAPSWPDDPTTETGKVESWSHGGGAPWQSASFDPETNTIIVGAGNPGPWNTWARTSKDGNPHDFDSLYTSGQVGVDPTTGEVKWFYQHTPNDAWDFSGNNELVLFDYKDKDGKQYKATAHADRNGFFYVVDRTNGKLKNAFPFVDNITWASHIDLKTGRPVENEGQRPAKPLPGETKGKPVEVSPPFLGGKNWNPMAYSQDTGLFYVPANHWKEEYWTEEVNYKKGSAYLGIGFRIKRMYEDHVGSLRAMDPTTGKVVWEHNERLPLWAGVLATKGNLVFTGTGDGYFKAFNAKTGEELWKFQTGSGIVSPPITWEQDGEQYIGVTVGYGGAVPLWGGDMAELTKPVAQGGSFWVFKIPAWDTKTAKR
What is the function of this protein?
Catalyzes the oxidation of ethanol and other primary alcohols to the corresponding aldehydes, except methanol, which is not a substrate (PubMed:7730276).  Uses a specific inducible cytochrome c550, encoded by the adjacent gene in the locus, as electron acceptor (By similarity).  Is a key enzyme of the carbon and energy metabolism during growth of P. putida on ethanol as the sole carbon and energy source (PubMed:18218017).  Displays lower activity on secondary alcohols, aldehydes and diols.  Is not active with sugar alcohols such as glycerol and D-sorbitol (PubMed:7730276).  In vitro, reacts well with phenazine methosulfate (PMS) as an electron acceptor but not with NAD(P), potassium ferricyanide, or molecular oxygen (PubMed:7730276).
What are the official names of this protein?
Quinoprotein ethanol dehydrogenase, QEDH, Quinoprotein alcohol dehydrogenase (cytochrome c), Quinoprotein alcohol dehydrogenase (cytochrome c550), Quinoprotein alcohol dehydrogenase ADH I, ADH I.
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SHC3_MOUSE
Sequence: MSATRKSRAGDEPLPRPPRGAPHTSDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQVTREAISRVCEAVPGAKGALKKRKPPSKMLSSILGKSNLQFAGMSISLTISTASLNLRTPDSKQIIANHHMRSISFASGGDPDTTDYVAYVAKDPVNRRACHILECCDGLAQDVIGSIGQAFELRFKQYLQCPSKVPALQDRMQSLDEPWTEEEGDGPDHPYYNSVPTKMPPPGGFLDARLKGRPHAPEAAQFAGKEQTYYQGRHLGDTFGEDWQRAPTRQGSLDIYSTAEGKTHMVPVGETPTYVNTQPVPPQVWPAATSSTESSPRKDLFDMKPFEDALRNQPLGPMLSKAASVECISPVTPRAPDARMLEELNAEPWYQGEMSRKEAEALLREDGDFLVRKSTTNPGSFVLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLINYHLESSLPIVSAGSELCLQQPVERKP
What is the function of this protein?
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons.  Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons (By similarity).
What are the official names of this protein?
SHC-transforming protein 3, Neuronal Shc, N-Shc, SHC-transforming protein C, Src homology 2 domain-containing-transforming protein C3, SH2 domain protein C3.
Protein: PSAC_WHEAT
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: Y723_THEVB
Sequence: MAQGQGFGFGLGKMKELAAAIQKAQQVQEGAKKLQEDLERMDIEGQAAGGAVKVIMSGTQEPRRVEISPDLLSEGAEVLSDLVTAAMRDAYQKSTATMRERMEELTGSLNVPGLG
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein tlr0723.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CHIC2_HUMAN
Sequence: MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD
What are the official names of this protein?
Cysteine-rich hydrophobic domain-containing protein 2, BrX-like translocated in leukemia.
What is the protein family that this protein belongs to?
Belongs to the CHIC family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasmic vesicle. Note=Also present at a Golgi-like vesicular compartment and at scattered vesicles.
Protein: RECX_STRZJ
Sequence: MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEEELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKWINDGQYAYAIINTNQLSGDKGPYVLTQKLSQKGISKSTIEENLKEFDFSEVAQRVANKLLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDKQYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_CLOPE
Sequence: MSKKPVMLMILDGFGISPNKEGNAVAAANKPNYDRLFNKYPHTELQASGLEVGLPEGQMGNSEVGHLNIGAGRIIYQELTRITKEIKEGTFFTNKALVKAMDEAKENNTSLHLMGLLSNGGVHSHIDHLKGLLELAKKKGLQKVYVHAFMDGRDVAPSSGKDFIVELENAMKEIGVGEIATISGRYYAMDRDNRWERVELAYNAMALGEGEKASSAVEAIEKSYHDNKTDEFVLPTVIEEDGHPVARIKDGDSVIFFNFRPDRAREITRAIVDPEFKGFERKQLHVNFVCMTQYDKTLECVDVAYRPESYTNTLGEYVASKGLNQLRIAETEKYAHVTFFFNGGVEQPNTNEDRALIASPKVATYDLKPEMSAYEVTDELINRLDQDKYDMIILNFANPDMVGHTGVQEAAVKAIEAVDECLGKVADKVLEKEGTLFITADHGNAEVMIDYSTGKPMTAHTSDPVPFLWVSKDAEGKSLKDGGKLADIAPTMLTVMGLEVPSEMTGTCLLNK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: SECA_BURVG
Sequence: MTTGFLQKIFGSRNQRLVKQYQKTVAAINALEPQIEKLTDDQLRGKTDEFRQRIAAGESLDKLLPEAFAVCREASRRVLKMRHFDVQLIGGMVLHYGKIAEMRTGEGKTLVATLPVYLNALAGRGVHVVTVNDYLAQRDAEWMARLYNFLGLSVGINLSGMEHDQKQQAYAADITYGTNNEFGFDYLRDNMVYETDARVQRALNFAVVDEVDSILIDEARTPLIISGQAEDHTELYVRMNALPPLLERQIGEEKADGTGVEKPGDYTLDEKSRQVFLTESGHEKAERLLAEWGLIGEGESLYAPQNITLMHHVYAALRAHTLFHKDQHYVVQNGEVVIVDEFTGRLMAGRRWSDGLHQAVEAKEHVKIQSENQTLASITFQNYFRMYAKLAGMTGTADTEAYEFNEIYGLETVVIPTNRPPKRIDKQDQIYKTAKERYDAVIRDIRECYERGQPVLVGTTSIENSELLSHLLTQAGLPHEVLNAKQHEREAAIVAEAGRPKRITIATNMAGRGTDIVLGGNAEKQAAFLEADDSIPPDEKARRIKQLHDEWETLHEQVKAAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLDDPLLRIFAGDRVRSIMDRLKMPEGEAIEAGIVTRSIESAQRKVEARNFDIRKQLLEYDDVSNDQRKVIYQQRNELLEAHDITETISAMRHGVITEVVHQFVPAGSIEEQWDVPELEEVLRNDWQLDLAIQEMVNESSSITAEEILEAVTSAADEQYEAKVAMVGRESFSAFERSVMLQTVDRLWREHLAALDHLRQGIHLRGYAQKNPKQEYKREAFELFAAMLDAIKQEVTRIVMNVQVQSPEQLEEAAEQIEEQGGHLENVEFQHADYAESGAPVANVAVAAAATADMVGSAMTHGGAGGEMPKVGRNDPCPCGSGKKYKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ENGB_ALIFM
Sequence: MSKTIHYQKTHFITSAPDIRHLPEDEGIEVAFAGRSNAGKSSALNRLTNQKSLAKTSKTPGRTQLINLFKVEENCHIVDLPGYGFAQVPLEMKKKWQKSLGEYLQKRQCLQGLVVLMDIRHPLKDIDQQLVFWAVDQNIPVQILLTKADKLKSGARKAQVLKVREAAVDFGGEVEVDAFSSLKGIGVDKLRAKLDEWFAPAFELDDEFIEDLDVE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PDXH_WOLPM
Sequence: MAVALIFATRARIKILFFDMIFSLEKDPFDLFSKWYKAVLNSPCEQPTAMTLATCSKDCIPSARVVLLKEYSKEGFVFFTNVNSKKGKELTENPKAALVFHWIEFARQVRIEGEVKLLNDERTDKYFSSRALGSQISAWCSKQSSILKDWQDFEQAIKLKEKEFHNTQVSRPDFWVGFCVIPKVIEFWQEGEYRKHIRFRYTLVEGSDWKVEQLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PGP_PYRHO
Sequence: MKIKAISIDIDGTITYPNRMIHEKALEAIRRAESLGIPIMLVTGNTVQFAEAASILIGTSGPVVAEDGGAISYKKKRIFLASMDEEWILWNEIRKRFPNARTSYTMPDRRAGLVIMRETINVETVREIINELNLNLVAVDSGFAIHVKKPWINKGSGIEKASEFLGIKPKEVAHVGDGENDLDAFKVVGYKVAVAQAPKILKENADYVTKKEYGEGGAEAIYHILEKFGYL
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate (By similarity).  Has phosphatase activity towards p-nitrophenylphosphate (in vitro).
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.