PharMolix/UniProtQA huggingface dataset:
Protein: OTC_PYRIL
Sequence: MRHLLTLMEYKPHEVENILRMSRDFKTRYLAGEVYTPIFPGRLVVLYFEKPSTRTRLSLTAAAAQLGMQAVYTTPSELQIGRGETIADTMRVLSRYAVAVAARVYRHETLEEMAQNSSISVINALSDKHHPLQALADALTLWEYVGKLHGIKVAFVGDVSNNVATSLAIIGAKLGWEVRLVGPKQLWNMKLVEELSEDLAKTGGRIYFTDSINDVAGVDGVYTDVWVSMGFEKEAEERRRMLKPYQVNQRVMEIAGRKAIFLHCLPAHRGEEVTDDVIDGPQSVVWDQAENRMHTAKAVFAYLLR
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_KLEP7
Sequence: MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGSADQHPRQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENARIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAARFSAEKEGWAPRRDQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEQGRELGLVDDERWARYNEKLESIERERQRLKSTWVNPQAESANEVNAHLTAPLSREASGEDLLRRPEMTYEQLVQLSPFTPGLEDRQAAEQVEIQVKYEGYIARQQDEIEKQQRNENTLLPATLDYRQVTGLSNEVIAKLNDHKPSSIGQASRISGITPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_DAUCA
Sequence: MSRYRGPRFKKIRRLGALPGLTNKRPRAGSDLRNQSRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVRIAGKAKGSTGQVLLQLLEMRLDNILFRLGMATTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITARDEQNSRALIQNSFNSPSQDEMPKHLTLQPFQYKGLVNQIIDSKWVGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCYL1_HUMAN
Sequence: MGNTLTCCVSPNASPKLGRRAGSAELYCASDIYEAVSGDAVAVAPAVVEPAELDFGEGEGHHLQHISDREMPEDLALESNPSDHPRASTIFLSKSQTDVREKRKSNHLNHVSPGQLTKKYSSCSTIFLDDSTVSQPNLRTTVKCVTLAIYYHIKNRDANRSLDIFDERSHPLTREKVPEEYFKHDPEHKFIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPTNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLNFLFAPLSKERAQNLEAISRLCEDKDLCRAAMRRSFSADNFIGIQRSKAILS
What are the official names of this protein?
Cyclin-Y-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin Y subfamily.
Protein: RHLB_ENT38
Sequence: MSKTHLTEQKFSDFALHAKVIEALENKGFHYCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSAFHYLLSNPAMADRKVNQPRALIMAPTRELAVQIHADAEPLAQTTGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPTPQRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADGHRVGLLTGDVAQKKRLRILEDFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLTAIETYIGHSVPQSKYNPDALLSELPPPKRLTRARSGNGPRRTGAPRNRRRPG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOK1_RAT
Sequence: MDGALMEGPLFLQSQRFGTKRWKKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGGSRRLDCKMIRLAECVSVVPVTVESPPEPGASAFRLDTAQRSHLLAADAASSTAWVQILCRTAFPKGGWALAQTENPPKFSALEMLENSLYSPTWEGSQFWVTSQKTEASERCGLQGSYVLRVEAEKLTLLTLGAQSQILEPLLFWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQAVEAAIQQQKAQGKVGQGQDITRTDSHDGETEGKMAPTPVPQEPLGSPPALYAEPLDSLRIPPGPSQDSLYSDPLGSTPAGAGEGVQRKKPLYWDLYGHVQQQLLKTKLIDSKEDPIYDEPEGLAPAPLRGLYDLPQEPKDAWWCQARLKEEGYELPYNPATDDYAVPPPRSSKPTPAPKPQGLILPESGTTAGSGSKGSDTALYSQVQKSGTPGRWDCGLSRVGNDRVGVKSEGST
What is the function of this protein?
DOK proteins are enzymatically inert adaptor or scaffolding proteins.  They provide a docking platform for the assembly of multimolecular signaling complexes.  DOK1 appears to be a negative regulator of the insulin signaling pathway.  Modulates integrin activation by competing with talin for the same binding site on ITGB3 (By similarity).
What are the official names of this protein?
Docking protein 1, Downstream of tyrosine kinase 1.
What is the protein family that this protein belongs to?
Belongs to the DOK family. Type A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL4_METBF
Sequence: MATAKTIDLTGKVVREIELPDVFDVDYRPDLIKKAVLAAQANRLQPYGPRLYAGMETSARGWGSGRGTSHVPRLVNSSRAARVPHARGGRRAHPPKPEADRSEKVNTKERRYAIRSAIAATRDPTLVSLRGHIFEAELPIVTENALEDLDKTKQVIEFLQAIGVYEDVLRAKYGRHIRAGRGKLRGRKYKHKKSVLIVAGESAPILKAARNLSGVDVATVDSLNAELLAPGTHAGRLTIWTESAVEKLEGAFQ
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: Y3323_BACC1
Sequence: MDMVAHAEINNLSFVYADENEKALQHISLSVQKGEFIALAGGSGSGKTTLLKHLKKELLPIGKRTGDTYYDGTLLENVPDLLSAQEIGMVFQNPENQLVMDTVIQELAFSLENIGLPSHIIQKRIAELISFLGFQDLLHQSVHTLSGGQKQLVNLAAVLVMQPKLLLLDEPTAQLDPIAAKEFLGLLKRINEELGITIVLSEHRLDEVIPLATRVICMNNGRIVYDGSPKRVIANMWEVEGFRPFIPQIPRLFLEWNAKDIPFTVREAQMKMNDFSAISYVNEPIVQREKQEVILSAEHISFQYEKNSPLILRDLTVSIEKGKWVALVGKNGTGKSTLLTILAGLQKARRGKVKWNGKVIHKIDSKERFKSIGYVSQHPYYHFTFDTVWDEVYERARELYGEQGKEIAEQQLKKFWLYALKERHPHDCSGGEQQLLALCTTLLSKPTLLLLDEPTKGLDPWKKERVGELFRKLQKEGTTIVMATHDIEFAAKYVDQCMMLFDGAVIMNDAPKEFFSGNFFYTTSINRFIRKELPYALTWEDVYEACPNDMLHS
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein BCE_3323.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS17E_THEVO
Sequence: MGSIRPFNVKRTAEEIAEKYPSLFTEKFEENKRKLEKMMPDVSKRTINIISGYLTRYVVKKKEKAEREIEENAAS
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: FUMC_SACS2
Sequence: MKYTDTAPKLFMNTGTKFPRRIIWSMGVLKKSCAKVNADLGLLDKKIADSIIKASDDLIDGKLDDKIVLDVFQTGSGTGLNMNVNEVIAEVASSYSNLKVHPNDHVNFGQSSNDTVPTAIRIAAVAEVTNRLLPALQQIISSLNKKAEEYKDVIKAGRTHLRDALPVTLGQELSAYADAFQHEHEQVMNILEYVKELPIGGTATGTGLNSHPEFQERVINEINRITGLGFKPANRFRAMRLLTDLLLLSGALRNIAVDLYRLGQDIRLMFSGPLTGLNEIDLPTQEEIAGSSIMPGKTNPVTVEATLLISAQVVGLDHANQFASMLGEFELSMGIPLVGYNIVTQVNFISEALEKMSRLVIDGMVANVEKMKRYAESSPSLITIVSPVIGYDKATEIGKKLNKGMSIREALRELGYSDNEINKILDLSKLVKPGFTAK
What is the function of this protein?
Involved in the TCA cycle.  Catalyzes the stereospecific interconversion of fumarate to L-malate.
What are the official names of this protein?
Fumarate hydratase class II, Fumarase C, Aerobic fumarase, Iron-independent fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2B_MYCTU
Sequence: MTGNAKLIDRVSAINWNRLQDEKDAEVWDRLTGNFWLPEKVPVSNDIPSWGTLTAGEKQLTMRVFTGLTMLDTIQGTVGAVSLIPDALTPHEEAVLTNIAFMESVHAKSYSQIFSTLCSTAEIDDAFRWSEENRNLQRKAEIVLQYYRGDEPLKRKVASTLLESFLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQRGLALVDDVTRAELKDYTYELLFELYDNEVEYTQDLYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVVTEDDDWDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.  Two genes for this protein are present in M. tuberculosis; this is the active form.  When coexpressed in E. coli with nrdE the 2 proteins complement a temperature-sensitive E. coli mutant.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit beta nrdF2, Ribonucleoside-diphosphate reductase nrdF2, Ribonucleotide reductase R2-2 small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: UBL4B_MOUSE
Sequence: MFLTVKLLLGRRCSLKVSGKESVATLKKLVSQHLQVPEEQQHLLFRGQLLADDKYLSDYSIGPNASINVIMRPPEDAALDKTHQTQPLWLQLGQVLDKHFGAKDAKTVLGFLRQEHEERLQRLSLEALEQLVGQLLAQQQLDELAEEKEAPAVASELEQNNGGGGGGGGTGGEGGGKKEEEEGEEADQ
What are the official names of this protein?
Ubiquitin-like protein 4B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXL16_HUMAN
Sequence: MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPPPPPTLPPPSLAAPLSRAALAGGPCTPAGGPASALAPGHPAERPPLATDEKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGSLRLLSLAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box/LRR-repeat protein 16, F-box and leucine-rich repeat protein 16.
Protein: RL16_SHEDO
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGTFGLKAVGRGRLTARQIESARRAMTRHVKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMDGVPESLAREAFALASAKLPIKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: URED_STAA3
Sequence: MDEQQWTGQLDLTVFFDGNRSVSRDIFFEKALKVIRPVYLNQSTIPTFYIVNVGGGYLDGDRYRMNVNVEDNAKVTLTSQGATKIYKTPSNHVEQYQTFNLKDNAYLEYVADPIIAYENAKFYQHNTFNLNNSSSLFYTDILTPGYSKTGEAFKYQYMHLINEIYIEDELVTYDNLLLNPNKQSINEIGYMEHYSHYGSAYFIHEDVNQKLIDSVYETISSYSNTFDCRVAISQLPTHGFAVRIFAYRTQIIEKILGTIQSYIAENIYDRKLDFLRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_SYNP2
Sequence: MGRVGVLLLNLGGPDKLEDVRPFLFNLFADPEIIRLPAPWMQKPLAWLISTLRAGKSQENYKEIGGGSPLRQITEAQGTALAQKLAEWGQEVKVYVGMRYWHPFTEEAIAEIKKDDLDQLVVLPLYPQFSISTSGSSFRVLEEMWRTDKDLNQLDYTLIPSWYDHPQYIAAMVDLIRQELDQFDNPDQAHIFFSAHGVPQSYVEEAGDPYQREIEECTKLIMEALGRPNDYTLAYQSRVGPVEWLQPYTEDSLIALGEKGVKDLVVIPISFVSEHIETLQEIDIEYREVAEEAGIENFRRVPALNTHPLFIESLANLVTDSLEQCPRTFGQVTHPKENMKMYPQELSWGMNTSAEVLNGRLAMIGFLALLLELISGQGPLHFVGIM
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_BARHE
Sequence: MVKAVTSSKETAKVEKKKSAPRSGVKKAVSKSQAGVKDSSSPVHKSSKKAPLAEAAVGVIKQVIGAVVDVQFEGPLPNILNALETDNLGNRLVLEVAQHLGENTVRTIAMDTTDGLVRGQKVFDTGTQISVPVGEATLGRIMNVIGEPVDNVGPIATSKTRSIHQEAPEYVEQSTASEILVTGIKVVDLLAPYSKGGKVGLFGGAGVGKTVLIMELINNIAKAHGGYSVFAGVGERTREGNDLYYEMIESRVNVNPKDNNGSTEGSKCALVYGQMNEPPGARARVALSGLTIAESFRDEGQDVLFFVDNIFRFTQAGAEVSALLGRIPSAVGYQPTLATDMGALQERITSTRTGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSFSRMLDPLIVGEEHYTVACQVQTILQRYRSLQDIIAILGMDELSEDDKLLVGRARKIERFLSQPFHVAEAFTGSPGKLVPLEETIKGFKGLCAGEYDNLPEAAFYMVGSIDEAVEKGKRLIAEVSS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HPPE_PSESX
Sequence: MDVRTLAVGKAHLEALLATRKMTLEHLQDVRHDATQVYFDGLEHLQNVAQYLAIPLSEFFVGQTQSDLDDGVKIARRNGGFKREEIRGGVHYYTYEHLVTTNQDPGLMALRLDLHSDDEQPLRLNGGHGSREIVYVTRGAVRVRWVGDNDELKEDVLNEGDSIFILPNVPHSFTNHVGGAKSEIIAINYG
What is the function of this protein?
Non-heme-dependent dioxygenase that catalyzes the oxidative epoxidation of (S)-2-hydroxypropylphosphonate into (1R,2S)-epoxypropylphosphonate, the final step in the biosynthesis of fosfomycin antibiotic.
What are the official names of this protein?
(S)-2-hydroxypropylphosphonic acid epoxidase, Hydroxypropylphosphonate epoxidase, Ps-hppE.
What is the protein family that this protein belongs to?
Belongs to the non-heme iron-dependent dioxygenase family.
Protein: SNORC_MOUSE
Sequence: MASCLALRVALLLISGVLAPAVLTAEGPQEPDPTLWNEPIELPSGEGPLESTSHNQEFAVSGPPFPTSAPAPEDSTPPARVDQDGGSLGPGAIAAIVIAALLATCVVLALVVVALRKFSAS
What is the function of this protein?
Plays a role in the regulation of chondrocyte maturation and postnatal endochondral ossification.  May inhibit cell growth stimulation induced by FGF2.
What are the official names of this protein?
Protein SNORC, Secondary ossification center-associated regulator of chondrocyte maturation protein.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Cytoplasm. Secreted, extracellular space, extracellular matrix. Note=Appears as reticular-like structures throughout the cytoplasm and adjacent to the plasma membrane (PubMed:21624478). In proliferation and hypertrophic chondrocytes, detected intracellulary and in the pericellular extracellular matrix. In primary spongiosa, detected only in the extracellular matrix (PubMed:28323137).
Protein: CUED2_RAT
Sequence: MELERIVSSALFAFVQTHLPEADLSGLDEVIFSYVLGVLEDLGPSGPSEENFDMEAFIEMMEAYVPGFAHIHRGIIEDMVQTLSVQLSSARNKETLRRPEKLKEESRPPAATGNTQDEAAAAEEEQPGVDVLLEVFPTCSMEQAQWVLAKARGNLEEAVQMLIEGKEEGPPGWGGPNQDLPRRLRGPRKEELKSFILQKYMMVDRAEDQKTHRPMAPKEAPKKLIRYIDNQVVSTKGERFKDVRNPETEEMKATYINLKPARKYRFH
What is the function of this protein?
Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation.
What are the official names of this protein?
CUE domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the CUEDC2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ODO1_BACCR
Sequence: MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFEIFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAANGQSLLEKAMSELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHIQDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLTAVEGFEQFLHKTFVGQKRFSIEGVDMLVPVLDEIVLEGAKNGVEDVMIGMAHRGRLSVLAHVLEKPYSHMFAEFKHAKIEGAVANSGWTGDVKYHLGREQVVSNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSGLPDQDTSKSFVILVHGDAAFPGQGIVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSYDSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRMLFKKDFLIDLIGYRRYGHNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQAAGVLNADEVETITQFTQEQLKSDYAQVPPADTSDATIHVKVPDVVAKGIQPIDTGVEIDSLRAINEGLLSWPEGFNVYPKVKKILERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTNETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQALFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSAAQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGMKPNKVKRLVLSTGKMAIDLAAEIESGKHEYNLDEVHVVRIEQLYPFPAEKVQSIIKRFKNLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQELIVAHALDVKYNFRQDKQEIEVYSN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: YFHK_BACSU
Sequence: MKKKQVMLALTAAAGLGLTALHSAPAAKAAPLHDISVSMPSSDTYIIKAGKLNVRTEPNHEGDILGTVSSEQKVKVDRFVNADWAQIHFKGKKAYISTHFLMKTASQAKTTKQTAFYTPTPENGKAKQLSSGTEVTILGWGFSENGGFDFTWAFVDYGGVKGYIHTKDLQMR
What are the official names of this protein?
Uncharacterized protein YfhK.
Protein: ARGB_BACCZ
Sequence: MSDYVVVKCGGSMLDQLNDVFFDCIKKLQQKYKVVIVHGGGPEIDAQLKDCNINVEKRDGLRVTPKEVMDVVQMVLCGSTNKKLVMNLQKHNLRAVGCSGCDGNLLQVQPVSEEIGYVGEVRYVETALLKGLINMNYIPVIAPVGINDNEIYNINADTAAAGIAAALSAKELIFITDVDGVLHEGKLVKKTDEFEIVNFIENGVITGGMIPKVQAAIASLKMGVQKVSIVNGMKDFTEVTGECIGTTVTRGVSIA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_ZYMMO
Sequence: MALLPILEVPDPRLREKSTVVEVFDDNLQRLIDDMFETMYKAPGIGLAAIQVGVAKRLLVIDLQQPEEGGEAKRNPMVFINPELTPEGEEKRLYNEGCLSVPDQYAEVRRPSVINAKWQDRDGNFHEERIEGLLATCLQHEMDHLEGILFIDHLSRLKRGMLMKKLLKERKLREDSY
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: FEZ1_HUMAN
Sequence: MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYILKVLCPT
What is the function of this protein?
May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery.  Able to restore partial locomotion and axonal fasciculation to C. elegans unc-76 mutants in germline transformation experiments.  May participate in the transport of mitochondria and other cargos along microtubules.
What are the official names of this protein?
Fasciculation and elongation protein zeta-1, Zygin I, Zygin-1.
What is the protein family that this protein belongs to?
Belongs to the zygin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell membrane. Note=Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity).
Protein: PPAC_STAHJ
Sequence: MAKTYIFGHQNPDTDAIASAIIMADFEQLTGNSEATPYRLGDINPETKFALDHFEVKAPELLSDNLDGREVILVDHNEFQQSAETISDAEIKHVVDHHRIANFETASPLWYRAEPVGCTATILYKMYKERGFEIKPHIAGLMISAIISDSLLFKSPTCTDEDVNAAKDLKDLANVDLDEYGLEMLKAGASTTDKSAEELLDMDAKSFNMGDYVTRIAQVNTVDIDEVLNRKEDLEKAMLETSANEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFKVQLDDGMAFLSGVVSRKKQVVPQITDALIK
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGF_VACCP
Sequence: MSMKYLMLLFAAMIIRSFADSGNAIETTLPEITNATTDIPAIRLCGPEGDGYCLHGDCIHARDIDGMYCRCSHGYTGIRCQHVVLVDYQRSENPNTTTSYIPSPGIVLVLVGIIIITCCSLSVYRFTRRTKLPIQDMVVP
What is the function of this protein?
Stimulates cellular proliferation (hyperplasia)and mobility around infected cells to promote rapid and efficient spread of infection.  This effect is beneficial for virus replication in vivo, because poxviruses replicate possibly better in proliferating cells than in quiescent cells.  Acts by binding host EGFR, inducing its dimerization, autophosphorylation and leading to activation of several cellular pathways regulating cell proliferation or cell survival.  The activation by host EGFR of mitogen activated protein kinases (MAPK) and extracellular-signal regulated kinases (ERK) are essential for the positive effect of vaccinia growth factor on poxvirus virulence in vivo (By similarity).
What are the official names of this protein?
Pro-vaccinia growth factor, Pro-VGF.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG019 family.
What are the subcellular locations of this protein?
[Pro-vaccinia growth factor]: Host membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Vaccinia growth factor]: Secreted.
Protein: RS2_XANOR
Sequence: MPQVTMRQMLEAGVHFGHQCRYWHPNMAQYIFGARGKIHIINLEKTVPLFNDAMNYLSSIAQKRGTILFLGTKRSARASIKEEAERCGMPFMTQRWLGGTLTNFRTVKQSVARLKELEAAETDGTFDKLVKHEVLSLRREREKLDASLGGIKEMNRLPDAIFVIDIGHEDIAIKEAKKLGIPVIAVVDTNYNPNLVDYAIPGNDDAIRAVQLYARAAADAVLEGKAAAPNSASVREEEFSAESADEGKGRRAPAKKGEKKADAPAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CYO9_VIOOD
Sequence: GIPCGESCVWIPCLTSAVGCSCKSKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cycloviolacin-O9.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: EX7S_LISMF
Sequence: MATKKKTFEEAIAELETIVEALENGSASLEDSLDMYQKGIELTKLCQDKLQSAEKRMAKVVTDAGEEIPFEADGE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4425_BACHK
Sequence: MKMTSKKMKDELMKKLSRPEWDFHYDSEKEVLRIEQKDSKKGINVSLPGVVAKWEVNKEKAIEEVAYYVQEALIAMHKEENSAAKILPVIRSTSFPKQAEEGNPFIMTDHTAETRIYYALDSNKTYRLIDERLLQKLGLTEQQVREMALFNARSLSYEFKQDTVAGNTFYFLNTNDGYDATRILNESLLQSMREKISGDMVVAVPHQDVLIIADIVNEIGYDIIAQMTMKFFAEGHVPITSLSFVYEDGDFEPIFILAKNRKKTDGKEKG
What are the official names of this protein?
UPF0354 protein BT9727_4425.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.