PharMolix/UniProtQA huggingface dataset:
Protein: 1A1D_BURM1
Sequence: MNLQRFPRYPLTFGPTPIQPLKRLSEHLGGKVELYAKREDCNSGLAFGGNKTRKLEYLIPDALEQRADTLVSIGGVQSNQTRQVAAVAAHLGMKCVLVQEHWVNYDDPVYDRVGNIQLSRMMGADVRLVPDGFDIGIRRSWEEALESVKQAGGRPYPIPAGCSEHPLGGLGFVGFAEEVRAQEAQFGLRFDYIVVCSVTGSTQAGMIVGFAADGRADRVIGIDASATPARTREQITRIARHTAELVDLGRDITDADVVLDTRYAGPEYGLPNEGTLEAIRLCARLEGVLTDPVYEGKSMHGMIDKVRRGEFEPGSKVLYAHLGGVPALSAYSAIFADG
What is the function of this protein?
Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate.  Allows growth on ACC as a nitrogen source.
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase, ACCD.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: XPT_STRA3
Sequence: MKLLEERILKDGDVLGENILKVDSFLTHQVDFELMQEIGKVFADKYKEAGITKVVTIEASGIAPAVYAAQALGVPMIFAKKAKNITMTEGILTAEVYSFTKQVTSQVSIVSRFLSNDDTVLIIDDFLANGQAAKGLLEIIGQAGAKVAGIGIVIEKSFQDGRDLLEKTGVPVTSLARIKAFENGRVVFAEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_STRTD
Sequence: MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEVAREALRLASHKLPVKSKFVKREAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DPO3_STAA8
Sequence: MTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEFHITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHAIKYFGHCIDQTALSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIFETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGKPIQIENIKPIESIIEEEFKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFTRKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRVEFHLHTAMSQMDGIPNIGAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMIYGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEIIDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASFDMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAIYDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKNLFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIAKYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFEHDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELADRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIGNGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKTSEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEYQPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGCTGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLDILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTEDEILCKTGTFGVPEFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRDDIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYSRYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPGLGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_SULIN
Sequence: MDFEQLLDKSLNKVREEIKTELSKSLDEAIKLLNEGHTKIIQEYTQRINELITKTKEEIEGEKARLEVENKRTLLVEKEYWINKVYERVLEKIGEVVKTKEYKDAIQSILNKEIKEIEGEKITVYCSPNDKSTVEKVVGNNKNVTIKTDDKMLGGIRIYYEGSGLTRDFSLKLILDQVFDSMRGKISDMLFGGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: PSAB_JASNU
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFESWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGSLGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLLAGWFHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPGSRGEYVRWNNFLEVLPHPQGLGPLFTGQWNLYAQNPDSSSHLFGTSQGAGTAVLTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSIKDLLDAHIPPGGRLGRGHKGLYDTINNSLHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTSGPAFNAGRNIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWLNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLIFWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: GAR1_USTMA
Sequence: MSFRGGGRGGGDRGGRGGFSSRGGRGGFGGGGRGGYANAGPPETVQPMGSFMHAVEGEMLCQSTDAKHVPYFNAPIYLENKSQIGKVDEILGPINEVFFTVKMDPGMVATSFKADDKVYISGDKLLPIERFLPKPKSLTKAPKKKGGARGGAAGGRGGFGGGRGAPRGRGGFGGGRGGARGGGFGAPRGGGRGAFGGGRGGAFSGGRGGAAGARGGFGGRGRGRGGY
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit GAR1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: Y904_BACCZ
Sequence: MIVTTTSGIQGKEIIEYIDIVNGEAIMGANIVRDLFASVRDVVGGRAGSYESKLKEARDIAMDEMKELAKQKGANAIVGVDVDYEVVRDGMLMVAVSGTAVRI
What are the official names of this protein?
UPF0145 protein BCE33L0904.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: ATP6_AERHH
Sequence: MSATGEVLTPQGYISHHLTHLQVGSGFWTVNIDSMIFSVLLGALFIWSFRRVAVKATSGVPGKLQCFVEMLVEFVSGNVKDIFHGRNKVIAPLGLTVFVWIFLMNLMDLIPVDFIPHAAQLMGVPYLRVVPSADVNITMSMALGVFFLILYYSIKVKGIGGFVKELTLQPFNHPAAIPVNLILETVTLISKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILSVPWAIFHILIITLQAFIFMVLTIVYLSMAQEDHG
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CO8B_ONCMY
Sequence: MNHKLKPTVGLGYCLLCAALCLLLLRDVAIAGSGEEPSGVREARSVGTQVAVQPVDCVQSEWSSWTRCDVCRKKRYRYAKLVQPSQFGGEPCHVQGKEVEPCSPPSRYDCTHDETPLCEGFLCTYTGRCVPIDLRCNGDDDCGDWSAEKGSPKVPKACKQEAQEYHGIENLAKGINILHSHLEGSVIDNRYYAGSCLPHYIQDVRFRKPYNLQQYTLETKGTYDFKLQSFESYSEFVHYTMTERSSKTTVSIGFALPGVAEFGFNYADSKYSKSEKKIRRASRKENSFVQAKAELQLARYILKSEDLMLHPEFFLRLRALPQSYNYGEYRQIYRDYGTHYITEATLGGDYEYTVILDKEKLEKTGYSLEAYKNCEQIVLKVGANIKGVYVTVGLEGGGCDGLLNEMGEDTVKGSMVEDYVAVVSGGDSESITWLAAKNLPTPPLMRLWGEAVHYNLDFIRSVTRPLYELVTARDFSSANSLKKNLRRALAEYLEESSSCRCAPCRNNGLAVLKGTRCECVCPSGYSGLGCEITQRPDIGIDGSWSCWGSWSPCRGRSKTRSRQCNNPAPSSGGIACRGLQMETTDCF
What is the function of this protein?
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
What are the official names of this protein?
Complement component C8 beta chain, Complement component 8 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUA_ECOL6
Sequence: MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGHGISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML
What is the function of this protein?
Responsible for the transport of C4-dicarboxylates during aerobic and anaerobic growth.  Required for the uptake of L-aspartate as a nitrogen source during aerobic growth.  The uptake of L-aspartate in aerobic conditions is coupled to the excretion of fumarate, resulting in the net uptake of nitrogen without carbon uptake.  In addition, during anaerobic growth, catalyzes the uptake of fumarate, malate or aspartate coupled to the export of succinate.  May play a a general role in anaerobic C4-dicarboxylate transport.
What are the official names of this protein?
C4-dicarboxylate transporter DcuA.
What is the protein family that this protein belongs to?
Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL36_RHOP2
Sequence: MKVRNSLKSLRARHRDNRLVRRKGRLYVINKVQRRFKARQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RPF2_CAEEL
Sequence: MVRVEKIKTKKGKRVLVNRASKTVENDKKALFCRGAKTNEIISHAMMDLFDMKKPLTTKMDKHNPYHLFEDETPIVRAGSKFDTSLFVLGSNSKKKPNCLTFGRTYDGQLLDMAELRITSYKSSSNFEAAKMTLGSKPCVILEGAAFESDGDMKRIGNLMVDWFRGPKVDTVRLEGLETVIVFTALDETNLALRVYRPMLKKSATATPRVELAEMGPSISFEVMRKKLADDALFKLACKKPKALMKKRRKNLSEDVFGNQLARVHVGKQRTDDIQTRKVKALRKTPLVEAAPENAIE
What are the official names of this protein?
Ribosome production factor 2 homolog, Brix domain-containing protein 1 homolog, Ribosome biogenesis protein RPF2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RPF2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TXLS1_PSETR
Sequence: LSLGTIKKLLQILAQGLKAICNHRDLIAKGCQA
What is the function of this protein?
This heterodimer may have anti-inflammatory properties, since the myrmexin complex (composed of 6 SS-LS heterodimers) inhibits carrageenin-induced edema in a dose-dependent manner (after subcutaneous injection into rats).
What are the official names of this protein?
U1-pseudomyrmecitoxin-Pt1 subunit LS1, U1-PSDTX-Pt1 subunit LS1, Myrmexin II subunit LS1/Myrmexin V subunit LS1/Myrmexin VI subunit LS1, U1-pseudomyrmecitoxin-Pt1b subunit LS1/U1-pseudomyrmecitoxin-Pt1e subunit LS1/U1-pseudomyrmecitoxin-Pt1f subunit LS1, U1-PSDTX-Pt1b subunit LS1/U1-PSDTX-Pt1e subunit LS1/U1-PSDTX-Pt1f subunit LS1.
What is the protein family that this protein belongs to?
Belongs to the myrmexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ODP2_STAAS
Sequence: MAFEFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKSVVEIPSPVSGTVEEVMVEEGTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPAKEEAPAEQAPVATQTEEVDENRTVKAMPSVRKYAREKGVNIKAVSGSGKNGRITKEDVDAYLNGGAPTASNESAASATSEEVAETPAAPAAVTLEGDFPETTEKIPAMRRAIAKAMVNSKHTAPHVTLMDEIDVQALWDHRKKFKEIAAEQGTKLTFLPYVVKALVSALKKYPALNTSFNEEAGEIVHKHYWNIGIAADTDRGLLVPVVKHADRKSIFQISDEINELAVKARDGKLTADEMKGATCTISNIGSAGGQWFTPVINHPEVAILGIGRIAQKPIVKDGEIVAAPVLALSLSFDHRQIDGATGQNAMNHIKRLLNNPELLLMEG
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: O163_CONTC
Sequence: MKLTCVLIISVLFLTASQLITAVYSRDKQQYRAARLRDEMRNLKGARDCGEQGQGCYTRPCCPGLGCRAGATGGGVCQQ
What is the function of this protein?
Ion channel inhibitor that inhibits the increase in intracellular calcium upon depolarization in DRG neurons.  In vivo, both intraperitoneal and intracranial injections into mice induce hyperactivity.
What are the official names of this protein?
Conotoxin Tr6.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_MORKA
Sequence: MTNIRKSHPLIKIVNDAFIDLPAPSNISSWWNFGSLLGVCLTVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYTETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VE4_HPV2A
Sequence: MEDSAAPRPAPRTTNHYPLLELLYPQSQPQSQPQQNQQEQEEQLRPPKRCAPPRRQRVRRPSASVSSSDSSIPGPTLRERSERGKWSVTTSGASVTLTAQTPGGATVTLTLCL
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: VL2_PCPV1
Sequence: MAHSRPRRRKRASATQLYQTCKASGTCPPDIIAKVEQNTLADKILKWGSLGVFFGGLGIGTGSGTGGRTGYVPVQTAPRPAIPFGPTARPPIIVDTVGPSDSSIVSLVEDSTIINSAASDFVPPIREGFEISTSETTTPAILDVSVTTHNTTSTSIFKNPAFAEPSIVQSQPSVEASGHVLTSTYTSTISSHSVEDIPLDTFIVSSSDSNPASSTPVPTPVARPRLGLYSKALQQVQVTNPAFLSSPQRLITFDNPAYEGEDISLQFQHNTIHNPPDDAFMDIVRLHRPAITSRRGIVRFSRIGQRGSMYTRSGKHIGGRVHFYTDISPISAAAEELEMQPLVAAAQDDSGLFDVYVDPTPGPVAVQNMSYPSSTSFVRSSMFTTKWGNTTVPLSLPSNIFAQPGPDIIFPAAPGVPPYNPVIPSLPITPIFISGSQFYLHPSLYLARKRRKRVSLFFADVAA
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: DEF_SYNS3
Sequence: MARSFAQLARSAEKSSSSIAVPKEPLETAPLDIHTLGDDALRGDARRIGKVDERVRDLARDMLRSMYTASGIGLAAPQVGVHQQLLVIDLDFETPSTPPLVLINPEITTCSASVDTYEEGCLSIPGVYLDVVRPTAIQLSFRDEMGRPRTMKADGLMARCIQHEMDHLRGVLFVDRVTDAGGLKKELKDHGFLATDVRPITP
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: GCSH_PSEA6
Sequence: MSNIPSDLRYATTHEWVRPEGDGTFTVGISEHAQELLGDMVFVELPDVGATVSAGDDIAVAESVKAASDVYAPIGGEIVGVNEDLEDSPELVNSDPYGDGWLFRIKADDADEVEGLLDAEGYENSIEEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RECA_WOLPM
Sequence: MASNPEERNSDKQKALDNAISQIEKAFGKGAIMKLKQNPVEKIDTISTGSIALDSALGVGGLPKGRIIEIFGPESSGKTTLALHVIAEAQKKGGSCAFIDAEHALDVLYARKLGVSTDDLVISQPDTGEQALHIVEYLVCSGAVDVIVIDSVAALTPRAEIEGDMGDQHMGLQARLLSHGLRKLTSAVSKANCILIFINQIRMKIGVVYGNPETTTGGNALKFYTSVRLDIRKVGVIKDKENITGNETRVKVVKNKVAPPFREAKFDIMYNEGISKLGEIIDMGAKLGVLEKAGAYYSYNNTRLGQGRENVKTYLKTNKEVANEIETKIRDLLRNHDNSIIIDEDSEQLLEESVF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_RHOBA
Sequence: MSVADSSAADSVAAPDTADTSSSVGVFSPPGYYDALAQQVLDGTPITREQALAMLEASDLDVPAIISAGYRIRHQYFGNTVQLYFLMNAKSGLCPEDCHYCSQSKVSDAPVPKYNILKRDALMDAAKVAAERGAKTYCLVISARGPNEREMKAVEEIVPEIKQKYNLDICACLGLLDESQAARLKACGVDRVNHNLNSSESHYEKICTTHTYEDRVQTLRHVRDAGMEMCSGGIIGMGESKSDIVSMAFDLNELGVQSIPVNILNAIDGTPLEGTAALTPQDALKALAMFRFVNPDRELRIAGGRELHLRQLQPMGLYVANSVFVGDYLTTQGQAPQADYDMIRDLGFDVTGSCEEMSI
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: TI11B_ARATH
Sequence: MSTGQAPEKSNFSQRCSLLSRYLKEKGSFGNINMGLARKSDLELAGKFDLKGQQNVIKKVETSETRPFKLIQKFSIGEASTSTEDKAIYIDLSEPAKVAPESGNSQLTIFFGGKVMVFNEFPEDKAKEIMEVAKEANHVAVDSKNSQSHMNLDKSNVVIPDLNEPTSSGNNEDQETGQQHQVVERIARRASLHRFFAKRKDRAVARAPYQVNQHGSHLPPKPEMVAPSIKSGQSSQHIATPPKPKAHNHMPMEVDKKEGQSSKNLELKL
What is the function of this protein?
Repressor of jasmonate responses.
What are the official names of this protein?
Protein TIFY 11B, Jasmonate ZIM domain-containing protein 6.
What is the protein family that this protein belongs to?
Belongs to the TIFY/JAZ family.
What are the subcellular locations of this protein?
Nucleus. SUBCELLULAR LOCATION: Nucleus. Cell membrane. Note=(Microbial infection) Interacts with Pseudomonas syringae HopZ1a at the plasma membrane and in the nucleus.
Protein: RECR_BURM7
Sequence: MSIKPPSALSELVEALRALPGVGPKSAQRIAYHLMQHDREGAERLGRSLLFATEHLRHCEKCNTFTEAQICEVCSDPERDPALLCVVETPADQIMLEQTMTYRGLYFVLMGRLSPLDGIGPKEIHFDRLVRRASDGIVKEVVLATNFTNEGEATAHYLGQTLKARGLAVTRLARGVPVGGELEYVDAGTIARAMLDRRTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: C19AA_DANRE
Sequence: MAGDLLQPCGMKPVRLGEAVVDLLIQRAHNGTERAQDNACGATATILLLLLCLLLAIRHHRPHKSHIPGPSFFFGLGPVVSYCRFIWSGIGTASNYYNSKYGDIVRVWINGEETLILSRSSAVYHVLRKSLYTSRFGSKLGLQCIGMHEQGIIFNSNVALWKKVRAFYAKALTGPGLQRTMEICTTSTNSHLDDLSQLTDAQGQLDILNLLRCIVVDVSNRLFLGVPLNEHDLLQKIHKYFDTWQTVLIKPDVYFRLDWLHRKHKRDAQELQDAITALIEQKKVQLAHAEKLDHLDFTAELIFAQSHGELSAENVRQCVLEMVIAAPDTLSISLFFMLLLLKQNPDVELKILQEMDSVLAGQSLQHSHLSKLQILESFINESLRFHPVVDFTMRRALDDDVIEGYNVKKGTNIILNVGRMHRSEFFSKPNQFSLDNFHKNVPSRFFQPFGSGPRSCVGKHIAMVMMKSILVALLSRFSVCPMKACTVENIPQTNNLSQQPVEEPSSLSV
What is the function of this protein?
Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
What are the official names of this protein?
Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1a, Estrogen synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.