PharMolix/UniProtQA huggingface dataset:
Protein: PDXB_SHEB5
Sequence: MKILVDENMPYVEPLFGDLGDIIPVNGRTLTAEQVGEADVLLVRSVTKVNAELLSGNNKLKFVGSATIGTDHVDLTYLAERNIPFSNAPGCNATAVGEFAFIAMLELAQRFNSPLKGKVVGIVGAGNTGTATAKCLQAYGIKVLLNDPIKAAEGDPRSFVSLETIMAQADIISLHVPITRTGEHKTKYLFDEARLKALKPNTWLVNCCRGDVIDNQALIKVKQQRDDLKLVLDVWEGEPTPLPELVPLAEFATPHIAGYSLEGKARGTFMLYQKLCQLLNITADKSLLDLLPTFNIKAVELATAPNEKALLQLARFVYDLRDDDKMFRNTFLNENGFDTMRKNHQHRREFSALALAYDGQSEVDWLSNLGFSGVGQ
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_SALPK
Sequence: MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: DCL1_MAGO7
Sequence: MEVHDGLKSPDKAAKSRYDDDRIDQDSEDEAVRLVANPDPSKPRKISERKRADQAAFESWVNDNKIRLSLPSATKSRRSGIRELFSSDETLETRPTRTRPRERVIEGPREYQIELFERAKQKNTIAVLDTGTGKTLIAILLIRHIIELELGARWQGREKRITFFLVDKVALVRQQTDHIRANLDFPVTGLHGDTVRNLWYSKEYFEKLLQEQEVVVCTAEILYRCLHRSYLNISQVSLVVFDEAHHAKKNHVYARIIKDFYLMEEDCQKRPRIFGMTASPIDTKDTCISYERATHELESLLHSEIATISDRDLLKVIGSRPQEVRKSYARVLRQENTELCNQLRELVGNHPLFKQTFDSAEFAVTELGAWCADKLWELCFREEAVSTLDGRVEGSRARDPDEVGESSHEVSNAREALSLVQQWSFSPPEDGSLSTKTHKLIEILAECFSQASAGNAIQCIVFVKRRDTAVLLNALCEQAEIRTKIPDLKGAFLIGAGRGGNAAFTTTRQQEQTVSRFRDGEINCLFATSIAEEGLDIPGCNVVIRFDLHGTTIQYIQSRGRARMRNSWFIHMTEFGNPEHNRRWFQDRVNEQKMRDFCLSLPKDRIMEKAEVDDVLRGDQSQKIFVVPGSKASLTFKQSLVVLAEFVATLPARPDEILSVDYTVVPVFGGFQGEVYLPASSPLRSAMGGVYRSKQLAKCAAAYAMCIQLYNSNYLDDHLKSTLAKVLPAMRNARLAVSSKKRKSYNMRTKPVLWSEVGPLTELYAMVLSLAQPGAAYYHSRPILLLTRKPLPEIAQFPLFFGKGSSRRSNVRCIPLAHPWSPTTTQVEGICAFTLCIFRDIFSKDFQASGTDMPYFLAPSTGIEHGTDLSSLVNPERIIDWATVHRTTTTDRVPYNFNEPDEFFQDKYVSDPFDGSRKFFMRKVRRDLKPQDKVPEGVPAPSKWRAVEHTILNYSVSLWKKSRAGHNSRQDQPVVEAELAPLRRNLLDETDGENSTGPQTCYLVLETLLISQIPVDTVVMAYTFPAIIYRLENSLISLEACQNLGLDIPIDIALIAMTKDSDNSDDHDEAPINFQSGMGQNYERLEFLGDCFLKMATSIALYTLVEGDEFEYHVERMLDICNKNLLNWALESNLQEHIRSKSFNRRTWYPPGLKLLKGKKTEVDDEHALGDKSIADVCEALIGAAYLTAQAQSSPNFDLAVKAVTVMTHSKTHTMQAWSDYYASYQCPEWLSTPPSQTQLELCSQIKNKMGYRFKNPRLLRCAFMHPSYPRQYENIPSYQRLEFLGDSLLDMVCVDYLFKKHPDKDPQWLTEHKMAMVSNQFFGCVAVGLGFHRHLIHMQPALGGSITEWAELVTKKREEARQLAVRRGQREEDYARDFWIEVHHPPKCLPDILEAYVGALFVDTGYDYSAVVGFFDRHIKPYFADMSIYDMYSSKHPVTHITSIITTQFGCSSFRLMVHEIPDDVQGEGLVTGAVKVVAACMIHGEVRCHAVAASGRYAKLAVAKQAVAIYEDMSPTEFRLRHGCNCKPEDGDGDHGVLVDHRADCEPEEPLRKQDPPAKSVVDVDGKTIAEMRLRHSKQMNDQEECLSW
What is the function of this protein?
Dicer-like endonuclease which seems not to be involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway, contrary to its DCL2 counterpart.
What are the official names of this protein?
Dicer-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: FBRL2_ARATH
Sequence: MRPPLTGSGGGFSGGRGRGGYSGGRGDGGFSGGRGGGGRGGGRGFSDRGGRGRGRGPPRGGARGGRGPAGRGGMKGGSKVIVEPHRHAGVFIAKGKEDALVTKNLVPGEAVYNEKRISVQNEDGTKTEYRVWNPFRSKLAAAILGGVDNIWIKPGAKVLYLGAASGTTVSHVSDLVGPEGCVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPAKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKSGGHFVISIKANCIDSTVPAEAVFQTEVKKLQQEQFKPAEQVTLEPFERDHACVVGGYRMPKKPKAATAA
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins (Probable).  Involved in pre-rRNA processing.  Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA (Probable).  Site specificity is provided by a guide RNA that base pairs with the substrate (Probable).  Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA (Probable).  Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (By similarity).  Acts as negative regulator of expression of immune responsive genes, including pathogenesis-related gene 1 (PR1), and of resistance against bacterial pathogen (PubMed:30307032).  Binds to MED19A, a positive regulator of PR1 expression, to repress the activator activity of MED19A (PubMed:30307032).  In response to the bacterial pathogen-associated molecular pattern (PAMP) elf18, associates with the long non-coding RNA (lncRNA) ELENA1 (At4g16355), and releases its repression of MED19A (PubMed:30307032).  Possesses ribonuclease activity toward rRNA in vitro (PubMed:29163603).  Binds phosphoinositides, phospholipids and phosphatidic acid in vitro (PubMed:29163603).
What are the official names of this protein?
rRNA 2'-O-methyltransferase fibrillarin 2, AtFib2, Fibrillarin-like protein 2, Histone-glutamine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Fibrillarin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Localizes to the fibrillar region of the nucleolus.
Protein: TM50A_MOUSE
Sequence: MSGFLEGSRCSECMDWGEKRNTIASIAAGVLFFTGWWIIIDAAVMYPRMDQFNHSYHTCGVIATIAFLMINAVSNGQVRGDSYSEGCLGQTGARIWLFIGFMLAFGSLIASMWILFGGYVAKEKDVVYPGIAVFFQNAFIFFGGLVFKFGRTEDLWQ
What are the official names of this protein?
Transmembrane protein 50A, Small membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the UPF0220 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOZ_WOLTR
Sequence: MAESVIEKCTEQVSNRFKLALLASQRTHDLNTGASNPVQSARFKGHKNTIISLYEIAERQVDTHELFSLLVSRCKEYMKGNLSNTYSSNTSKLEKLLNFSNDQFNTDADVDQESTDIQDDEVENEMSNQDSEDIDDEVDNEE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RPO3B_TOBAC
Sequence: MASTASYSPSPTSQWRTQKLPKRFNFYVIHNQEFGKLSQSSSLSTSSFPKTLKLPVIHMPINNIQSQTTVCVSTDENLEELVNLQKIPNGFLNKESNKRVFIQDPPWVSSLFMNSLFVRAKQVQGVRREFREIERRRRYAMLRRRQIKAETEAWEQMVEEYRELEREMCEKKLAPNLPYVKKLLLGWFEPLRQAIEKEQNAETTVKHRAAFAPHIDSLPADKMAVIVMHKLMGLLMMGGKEERCVQVVQAAVQIGMAVENEVRIHNFLEKTKKLQKHMTGAQSQEDMSKETMILRKRVKSLIKRNRVVEVRKLMKSEEPESWGRDTQAKLGCRLLELLTETAYVQRPVDQSADTPPDIRPAFRHVFKIATRDPGKNIVKKYGVIECDPLVVAGVDRTVKQMMIPYVPMLVPPKKWRGYDKGGYLFLPSYLMRTHGSRRQQDAVRGVPTKQMQQVYEALDTLGSTKWRVNKRILNVVESIWAGGGNIAGLVDRKDVPIPELSNSDDIMEVKKWKWKVRKSKKINQELHSQRCDTELKLSVARKLKDEEGFYYPHNLDFRGRAYPMHPHLNHLSSDLCRGILEFAEGRPLGKSGLRWLKIHLASLYAGGVEKLCYDARLAFVENHIHDILDSANNPLNGNRWWLNAEDPFQCLAACINLSEALKSSSPHTVISHLPIHQDGSCNGLQHYAALGRDSMEAAAVNLVAGEKPADVYTEIALRVDHIIRGDSIKDPAIDPNALLAKLLIDQVDRKLVKQTVMTSVYGVTYVGAREQIKRRLEEKGLIDDDRLLFTASCYAAKVTLAALGELFQAARGTMTWLGDCAKVIALENQPVRWTTPLGLPVVQPYFKTQRHVIRTSLQILALQREGDAVEVRKQRTAFPPNFVHSLDGSHMMMTAVACRDAGLQFAGVHDSFWTHACDVDQMNRILREKFVELYSLPILEDLLENFQKSYPALTFPPLPKRGDFNLREVLESPYFFN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase 3B, chloroplastic, NictaRpoT3-tom, T7 bacteriophage-type single subunit RNA polymerase 3B.
What is the protein family that this protein belongs to?
Belongs to the phage and mitochondrial RNA polymerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOB_STAAT
Sequence: MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREGLIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDATIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLRNTLEKDGTENTEQALLEIYERLRPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTNKKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMDVLESNANSEVFELHGSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLSGIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQIDYLTADEEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVEHVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSGTCYNQRPIVAVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CYB_NEUCR
Sequence: MRLLKSHPLLKLVNSYLIDASQPSNISYLWNFGSLLACCLIIQIVTGVTLAMHYSPNVLEAFNSIEHIMRDVNNGWLVRYLHSNTASAFFFLVYLHIGRGMYYGSYRAPRTLVWAIGTVILILMMATAFLGYVLPYGQMSLWGATVITNLISAIPWIGQDIVEFIWGGFSVNNATLNRFFALHFVLPFILAALVLMHLIALHDTAGSSNPLGVSGNYDRITFAPYYLFKDLITIFIFIYVLSSFVFFMPNVLGDSENYIMANPMQTPPAIVPEWYLLPFYAILRSIPNKLLGVIAMFSAILAIMLLPITDLGRSKGLQFRPLSKFAFWAFVVNFLILMKLGACHVESPFIELGQFSTIFYFSYFIFIVPVLSLIENTLVDLNYLK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (PubMed:3015618) (Probable).  Cytochrome b is a catalytic core subunit containing 2 b-type hemes BL and BH topographically segregated in the quinone reduction (Qi) and quinol oxidation (Q0) sites on opposite sides of the membrane (By similarity).
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome c oxidoreductase complex cytochrome b subunit, Ubiquinol-cytochrome c reductase complex 30 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: AMPA_DESDA
Sequence: MDIRFQNLGPEHWKGEIMLAPVCQDEVLTEICPQMDKAAPWLAIAPALRDFKGKTGELALMHGHPELAVPRVLAVGLGPREKVDTAGIRKAVAAAVQLCRQKGFGSILLPEPALARLPGGRERLVEECVCASLLALYRFTALKKAEKDEPAEPQWLALGFDGQEVPDASHAAARKGENAAWAVMLARDLASTPPNLLYPEKLAERARELAREKGFACTVLDEHELEKESMGCLLAVGQGSGRPPRLVILEHAPEGHEQEKPLILVGKGITFDTGGISLKPAANMHQMKADMTGAATVLATLAALAQEDAPRRVIGLLACAENMPGGRAMRPGDVVRAANGDSVEIQNTDAEGRLALCDALAYAQKTWTPAALVDIATLTGACAVALGTQIAGLFSDDADLAERIRAAGGACGEEYWPLPLWKPYAEQLKSDVADICHMGPREGGAINAALFLQHFIQEGVRWAHLDIAGVDWVSKPTPLCPAGPSAFGARTLLELARGGVL
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB5A_ORYSJ
Sequence: MAANPGNKIRNAKLVLLGDVGTGKSSLVLRFVKGQFVEFQESTIGAAFFSQTLAVNDETVKFEIWDTAGQERYHSLAPMYYRGAAAAIVVYDITNAASFTRAKKWVQELQAQGNPNTIMALAGNKADMVEARQVPAEEAKTYAQENGLFFMETSAKTAINVNDVFHEIAKRLLQGQQAQDTPAGMVLNQRPAERMVSSSSCCS
What is the function of this protein?
Plays an important role in intracellular trafficking of seed storage proteins to the protein storage vacuoles (PSVs) (PubMed:21105928).  Participates in the transport of the proglutelins from the Golgi apparatus to the PSVs in endosperm (PubMed:21825104).  Functions cooperatively with VPS9A to regulate post-Golgi dense vesicle-mediated transport of storage proteins to the type II protein bodies (PBII) protein storage vacuoles in developing endosperm (PubMed:23723154).  Involved in the maintenance of the general structural organization of the endomembrane system in developing endosperm (PubMed:21105928, PubMed:21825104).  Binds GTP in vitro (PubMed:21105928, PubMed:21825104, PubMed:23723154).  Forms a quaternary complex with the two glutelin zipcode RNA-binding proteins RBP-L and RBP-P, and the membrane trafficking factor NSF (PubMed:32471860).  This quaternay complex carries glutelin mRNAs for active transport on endosomes to the cortical endoplasmic reticulum membrane, and enables endosome-mediated glutelin mRNA transport in endosperm cells (PubMed:32471860).
What are the official names of this protein?
Ras-related protein Rab5A, OsRab5A, Protein GLUTELIN PRECURSOR 4, Protein GLUTELIN PRECURSOR ACCUMULATION 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Prevacuolar compartment membrane; Lipid- anchor. Golgi apparatus membrane; Lipid- anchor. Cell membrane; Lipid-anchor. Protein storage vacuole membrane; Lipid-anchor.
Protein: PANC_MYCBP
Sequence: MTIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLALVRAAKRVPGSVVVVSIFVNPMQFGAGEDLDAYPRTPDDDLAQLRAEGVEIAFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIVRPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNRYLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYLELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYRAILESHWRN
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF73_ORYSI
Sequence: MTKDETLLVFTLVVSSVSVFLFGILLFMVLISATRDFRERTKSKLVKIMIWAGIVVITFAIAVRIYPIFIFLLKERIKPLVEALYDKLPWIWEVSLSRYWDRLIDFLDRYLWACAQRIQTGIRKQKGEFVVTFSCRVKKRLYARAIEVGIHLSLLSNLFWILKTTLAVGYRLLWVLYYIISFEGFLGSFRLYLVYFGFYCLLFSGKWLRTSEDRGERQAQISGILLRGMLIECAFSVLCLEEDSNLHAL
What are the official names of this protein?
Uncharacterized protein ycf73.
What is the protein family that this protein belongs to?
Belongs to the ycf73 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYST_HELSJ
Sequence: MGNFILHPIQSRLIVISYSILILILPLYALFSYASNASWSLILEKATDPIAVAAYTLTIKMALYTAIINTIFGFIIAWVLTRYNFSGKRIMDAIVDLPLALPTSVAGLALSTVFGRNGLFGHILDFYNYEIIYTKRGILLAMIFVSFPFSVRAIQPILKEINKEEEEAAWSLGSGPLETFKRFIFPIILPAILNGFTLTFSRSLSEFGSIVMVAGNLPLQDLVSSVLISQYLEQYDYIGACVISIIVLMLACSVLLFVQIIHSLVVVDSK
What is the function of this protein?
Part of the ABC transporter complex cysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Probable sulfate transport system permease protein cysT.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: MALK_VIBCH
Sequence: MASVTLKNVCKAYGDVLISKNVDLEIQEGEFVVFVGPSGCGKSTLLRCIAGLEDITSGDLYIGEQRMNDVEPSKRGVGMVFQSYALYPHLNLYDNMSFGLKLSKADKSEIKKRVDHAAEILQLSHLLDRQPKALSGGQRQRVAIGRTLVSQPNVFLLDEPLSNLDAALRVQMRSEITKLQRKLGCTMIYVTHDQVEAMTMADKIVVLDAGFVSQVGKPLELYHYPQNRFVAGFIGSPKMNFMSVFIEGVEKDRVQVQLSNGTTFWIPVDGTTVTRGERMSLGIRPEHLVEAEHGDAKIEGKVMIVEKLGNETQVYMNLKGSDSDVIYRQPDTLDVETGDTLTIGIPAHRCHLFHSDGRACRRLHKEKGVDLPA
What is the function of this protein?
Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Maltose/maltodextrin import ATP-binding protein MalK.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ECPE_ECOL6
Sequence: MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFVSKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFYYHGPRDNRERYYRVSFREVPTRNLTKRSPSGGEVSTEPVVVMDTILVVRPRQVQFKWSFDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYNDKFIKISDSCPAKPPSAD
What is the function of this protein?
Part of the ecpRABCDE operon, which encodes the E. coli common pilus (ECP).  ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition (By similarity).
What are the official names of this protein?
Probable fimbrial chaperone EcpE.
What is the protein family that this protein belongs to?
Belongs to the EcpB/EcpE family.
Protein: BRLA_ASPFU
Sequence: MRSQGNMSDRLGVEVDCHSLGSNECPSMGSSFSPLESPTPTPTSIYSQGSLASPSWPENGSYPGHAYDRGTGSTPIRGHFRLASMPSHENMGLPPYSSLDGQDRMAVTDFLPSYDENADQFWLPSDVPKTYDHHVHGLPCPPSMHQYPPMLRSNYRHHPAPYFPESATNPCLSRPIFHHQPERLPPSLSMSHMMPWMGHTESIAPETIAPSQVAPVTPPPSYTDFSNSINTFKTHSPDTPIRSCSLGTVSGADTPLSRLSGGAGEYMDECHQSPIYRDASGVRLQRQPSRKMARKQPSKQSLSLENLPSIIKQVQFKCKEPGCKGRFKRQEHLKRHMKSHSKEKPHVCWVPGCHRAFSRSDNLNAHYTKTHSKRGGRNRYVATLDETSPDYNPDYRGPLTADGRPMPGGTLDESMPSREISMEWDE
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (PubMed:17030990).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).  Binds promoters of target genes at brlA response elements (BREs) containing the conserved sequence 5'-(C/A)(A/G)AGGG(G/A)-3' (By similarity).  Positively regulates expression of the gliotoxin biosynthetic gene cluster in actively growing vegetative cells, and likely bridges morphological and chemical development during the life-cycle (PubMed:26032501).  Regulates (directly or indirectly) the ergot cluster genes (PubMed:18333504).  Positively regulates expression of the fumiquinazoline C biosynthetic gene cluster (PubMed:24612080).  Positively regulates expression of the melanin biosynthetic gene cluster (PubMed:24123270).  Mediates repression of ribosomal protein gene expression in response to nitrogen depletion (PubMed:19028996).
What are the official names of this protein?
C2H2 type master regulator of conidiophore development brlA.
What are the subcellular locations of this protein?
Nucleus.
Protein: IF2_THET2
Sequence: MAKVRIYQLAKELGMETQELLELLDQMGVAYKSHASTLEEKDAEAVRELVKEQRGLQEKLAEEERRKSLPRRPPVVVIMGHVDHGKTTLLDYLRKSRIAEKEAGGITQHVGAFEVKTPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGIMPQTEEAIAHAKAAGAKLIFAINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPISAKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILESKLDKQAGIIANMLVQEGTFRVGDYVVAGEAYGRIRAMMDADGNQRKEAGPGSAVQVLGFQELPHAGDVVEWVPDLEAAKEIAEERKEERKAREEEEKARRPRTMAELLRAMQEEGRKELNLILRADTQGSLEAIQHILARESTEDVKINILLAQVGAPTESDVLLAQTANAAILAFGVNPPGSVKKKAEEKGVLLKTFRIIYDLVDEVRNMVKGQREPQYKEEVLGQAEVRAIFRLPTGKQVAGCMVTQGRIPRNAEVRVLRDGQVIWQGRIASLKRFKEDVREVAQGYECGIGLDGFDDFREGDVIEAFQMVEVPA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRE11_SACS2
Sequence: MVQILHISDTHLGKRQYSLVEREKDIYDIFSQLVDIAIKEHVDVIIHSGDLFDVSSPTTNALVMAIKILKRLKDVNIPFLSIPGDHDTPKRKGYLIPHNILSELDLIKILNYEKPYIIKGIEVYGIPHIPTVSKSILVSALSALRPKSSRSILLLHQGVKQILPYDGSWQMELGSLPKGFGYYALGHIHTRWRLTQDDGSVIAIAGSPDIMREEEIEGYEKFGKGAYLIDFSKDLPILSTINITVRPQKVVTINTKNIKKDILTIRDDLIEHNKSENNKPILHIIVEGERMRKDLLYKELLPLNDVALYYRIYKDETTQTVDNLSYTLPRDKGLDKIIIEYLTKYEKFSEDEANLILQMIKNVESDEIVNEILKKLTGVNL
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity.
What are the official names of this protein?
DNA double-strand break repair protein Mre11.
What is the protein family that this protein belongs to?
Belongs to the MRE11/RAD32 family.
Protein: RL7_XANOM
Sequence: MSLTNEQIVDAIAEKSLMEVMELVKAIEDKFGVSAAAPVAAAAAAGPAAVVEEQTEFTVVLTNPGLNKVTAIKAVRGVTGLGLKEAKDLTEAGGILKEGVSKDEAEKIKKEMTEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PUR7_ESCF3
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.