PharMolix/UniProtQA huggingface dataset:
Protein: GP17_BPPH2
Sequence: MNNYQLTINEVIDIINTNTEINKLVAKKENLFPTDLYDLDKQELIAIILNSDFALSSIKRVLLEVTVEELGTQDNDEDDELEDLDGEIDRVDYIDKDGIRFDVPRETSPHVDKSIVTFNDELLDEANKIAKSIQEHDFNDKAIEEAELKIFKNHLPSIYSMKKENK
What is the function of this protein?
Involved in the replication of viral DNA (PubMed:9858710).  It is required at the very beginning of the virus amplification, conditions in which a low number of viral DNA molecules enter the host cell, possibly to recruit the limiting amount of initiation factors at the replication origins (PubMed:9858710).  Once the infection process is established and the other replication proteins reach optimal concentration, it becomes dispensable (PubMed:9858710).  Optimizes the binding of protein p6 at the viral DNA ends, thus favoring the initiation of replication (PubMed:12480935).
What are the official names of this protein?
DNA replication protein 17, Gene product 17, gp17, Protein p17.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus protein p56 family.
Protein: RLMM_XANC8
Sequence: MSGLLCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAARLQWRELIFARQKLVVLAELKGLDPKDRITPILAALDGQPRFGDLWVEHPDSDAGKPLAGLARSFGNALRPALRKAGLLTDKPQARLPRLHICFLDGDHALLAVADSSDSAPWPLGIPRLKLLPEAPSRSALKLDEALLTLLTPEEREQLVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPLREHVLATGLVEHLRADGFHWKPAQPLDWMVCDMVEQPRRVAERMATWVREGWCRHTIFNLKLPMKKRWDETRLCLDLFEQQAEKSLTVRAKQLYHDREEITVLAMRG
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G1PDH_SULTO
Sequence: MELKEHIIDLPKKVYIGYDIIDNIKEYILSLNLSGPFLIVTGPLVRKIITDKIIENFKDESVEVVEVKIASIDEVNKVEEMAKGSRINTIIGVGGGNIIDVAKYVAYRIGKEFVSLPTAPSHDGITSPFASIKGLGKPTSVKAKGPIAIIADINVLASAPRRLINAGIGDTIGKITAVRDWQLAAKLRGEYYGDYTASLALMSAKHALSCAKILDKDVRAGVRVLTEALISSGVAMGMAGSTRPASGSEHLFAHAIEILYPDKALHGELVALGTILMAYIHGINWKKIKKAMKKVGLPTKAKQLGIPDEIIIKALTIAHTIRPERYTILGDRGLTWEAAEKIAKETGIID
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTC_SALA4
Sequence: MSLSVTRENFDEWMVPVYIPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMHYGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNTLNVRFGMFSEIRGLGLLLGCVLQTKFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQAGGASCG
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: TCL1B_HUMAN
Sequence: MASEASVRLGVPPGRLWIQRPGIYEDEEGRTWVTVVVRFNPSRREWARASQGSRYEPSITVHLWQMAVHTRELLSSGQMPFSQLPAVWQLYPGRKYRAADSSFWEIADHGQIDSMEQLVLTYQPERKD
What is the function of this protein?
Enhances the phosphorylation and activation of AKT1 and AKT2.
What are the official names of this protein?
T-cell leukemia/lymphoma protein 1B, Oncogene TCL-1B, Oncogene TCL1B, SYN-1, Syncytiotrophoblast-specific protein, TCL1/MTCP1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TCL1 family.
Protein: ISPE_MOOTA
Sequence: MDVLTLPAYGKINLTLKVLGRRSDGYHNLSTIFQSIALADRLTFSRCREGIRLETSGLPVPQGPENLAYRAAARLQSRYGFPGVRITLKKQIPLAAGLAGGSADAAATLIGVNALFNLGLTPGQLAREGAALGSDVPFCVIGGTALGRGRGEELSLLPPLPTLWLVLVKPSFGVSTAAVYRGWDASPGQTPMEAPDEERALAAIRRGDRAGIMASLGNDLEAVTCRLYPEVMAIKMRLLAEGAERAVMCGSGPAVFGVAADGETARRIASRLQETYPETIVTRTL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ATPF_NOSP7
Sequence: MGIMGTFLLLAAEANAVHSELAEGAAEGGFGLNLDIFETNLINLAILVGILFYFGRKVLSNILNERQSNIATAIQEAEGRLKEAKTALSQAQEQLKQSQAEAERIRQSAVENAQKAKEALLAKAVQDVERLKQTAAADLNTETERAIAQLRQRVATLALQKVESQLKGGIADDAQQSLIDRSIAQLGGNV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CBID_PROM9
Sequence: MKKGFSLPLWVAGAARSALKKLVGLPFDNYELIKIPNEKKEIKIEIHSVGLLKDDSHALGISFAKSGLYLDITQNLEIWTIASLERNSFNNPLQTNPINIIAGSGVGIKEDTSEICISDFAKEVLYENLLDIIPEGFNLKLEIIFPNGVFLAERTSNKSFGIVDGLSIIGTSAETYSSASPDQLEEAKTNLAKLVQNDFKGKVVFVIGENGLNLAKNCNLKFPILKVGNWIGPLIVDAAIKKVKTVILFGYHGKLIKLAGGIFHTHNHLADGRIEILVYLAVQEKVPTEIIVQLSHLKNLEEALLLLERFDKSIAEKLFLNLSNTIEKRSFTYVNRYVKTDMEIASIIFDRKREIRWAGTYGNKYISDFQ
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: Y231_METJA
Sequence: MDLEKLIKIGEKEGFETEVLFVKSYEVSVDLDGKSVDSFQTGISYGIGVRVIKDGKVGFAYANKFDENIVYKAMKNLVEDKYTEFAHPQKYKEPKGMFYKEILDLDEEKLLEDLITMRDIALDNNAIVLSGGVSKEVGYARLINSNGVDVEEQDTYFSAAISIMYDGETSYECRTRHNIFDVEEISYRALDLAKKSANGKAISYKGNIVLSPRALYDLLSYTLMPAFSAENVQRDRSVLKGKIGEQIFGENITIIDDGTLDYALYSSKCDGEGTATQKTVLVENGVLKNYLYDIKRANREGKTSTGNASRGYRSLPYVSPTNFIIKETKNSLDDFDEYVYINGVIGSHTSNPITGDFAVEIQNSYYYKNGKIIPIKRGMFGGNIFEMFKEAIPLNDVEQRGKLISPSVVFKGEIIN
What are the official names of this protein?
Uncharacterized protein MJ0231.
Protein: Y552_ARCFU
Sequence: MAIKVRLPASINQGDLEIDAEKLTVNQLIALLSQITGKDLEKILKRDGELSPFISIFVNGRNVRYAEGLETEVRSGDEVSIVPTVAGG
What are the official names of this protein?
Putative sulfur carrier protein AF_0552.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein CysO family.
Protein: TFXA_RHILT
Sequence: MDNKVAKNVEVKKGSIKATFKAAVLKSKTKVDIGGSRQGCVA
What is the function of this protein?
Antibiotic whose production provides the bacterium a mechanism of host root nodule competitiveness with other invading inefficient strains.
What are the official names of this protein?
Trifolitoxin, TFX.
Protein: PFLA_STAA3
Sequence: MLKGHLHSVESLGTVDGPGLRYILFTQGCLLRCLYCHNPDTWKISEPSREVTVDEMVNEILPYKPYFDASGGGVTVSGGEPLLQMPFLEKLFAELKENGVHTCLDTSAGCANDTKAFQRHFEELQKHTDLILLDIKHIDNDKHIRLTGKPNTHILNFARKLSDMKQPVWIRHVLVPGYSDDKDDLIKLGEFINSLDNVEKFEILPYHQLGVHKWKTLGIAYELEDVEAPDDEAVKAAYRYVNFKGKIPVEL
What is the function of this protein?
Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
What are the official names of this protein?
Pyruvate formate-lyase-activating enzyme, PFL-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPH19_ARATH
Sequence: MSGSLAFHIIMSVTFMVFFFGGLCEARGVNVDLINDIGPNVQLGLHCKSKNKDLGSQSLVSDQHWGFRASLGFWTVTLFFCHFEWENQSKWFDIFVEDRDLTCGDHCVWSIRPSGPCRLTGREKCFPWNNKY
What are the official names of this protein?
S-protein homolog 19.
What is the protein family that this protein belongs to?
Belongs to the plant self-incompatibility (S1) protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPB_RHIE6
Sequence: MNETPKPNSFRSGPDEDGRFGIYGGRFVAETLMPLILDLQDEWNKAKTDPAFQAELQHLGAHYIGRPSPLYFAERLTAELGGAKIYFKREELNHTGSHKINNCIGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCVVYMGATDVERQAPNVFRMKLLGAEVKPVTAGSGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPEMVRDFQSVIGAEAKEQMLAAEGRLPDLVVAAVGGGSNAIGIFHPFLDDPSVKIVGVEAGGKGLQGDEHCASITAGSPGVLHGNRTYLLQDGDGQIKEGHSISAGLDYPGIGPEHSWLSDIGRVDYVPIMDHEALEAFQTLTRLEGIIPALEAAHAIAEVIKRAPTMSKDEIILMNLSGRGDKDIFTVGKILGMGL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SAU54_ARATH
Sequence: MAIINRSKLTQTTMIKQILKRCSSLGKKQSSEYNDTHEHDGDSLPLDVPKGHFVVYVGGNRVRYVLPISFLTRPEFQLLLQQAEEEFGFDHNMGLTIPCEEVAFKSLITSMLQPTYI
What is the function of this protein?
Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e. g.  AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion (By similarity).  Triggers plant growth probably by promoting cell elongation (By similarity).  Regulates branch angles and bending (By similarity).
What are the official names of this protein?
Protein SMALL AUXIN UP-REGULATED RNA 54.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FMT_ACIF5
Sequence: MTEKQRIVFAGTPEFARITLAELRQGPEAVVGVFTQPDRPAGRGRTLQASPVKQEALAAGIPVFQPESCKTGEALELLRSLAPDLLIVVAYGQILPQAILALPTRGAINVHASLLPAWRGAAPIARAIAAGDKESGVAIMQMEAGLDSGPVLWEERLPIAADDTAASLHDRLARLGGKALRHVLDDLWAERLKPVPQDPALVTYAHKLKKEEALLDWRLPAATLERLVRAFNPSPVAHTLFRDKGLRVWQARVLGAGGDQAPGSISAVEKDGVVVTCGEDRLQLLAVQPAGKGVLSGSDFARGYRPQVGEVLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: STF1_BOVIN
Sequence: MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPVGVPPPPPPPPDYMLPHGLHASEPKGLASGPPAGPLGDFGAPALPMAVPSAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGPPYGYPEPFSGGPGVPELILQLLQLEPDEDQVRARIVGCLQEPAKGRPDQPAPFSLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQIQHGKEGSILLVTGQEVELTTVAAQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKFLILFSLDVKFLNNHSLVKEAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
What is the function of this protein?
Transcriptional activator.  Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues.  Binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B.  Also regulates the AMH/Muellerian inhibiting substance gene as well as the AHCH and STAR genes.  5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1.  The SFPQ-NONO-NR5A1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional activity.  Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3.  Activated by the phosphorylation of NR5A1 by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation (By similarity).
What are the official names of this protein?
Steroidogenic factor 1, SF-1, STF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CBPB1_RAT
Sequence: MLLLLALVSVALAHASEEHFDGNRVYRVSVHGEDHVNLIQELANTKEIDFWKPDSATQVKPLTTVDFHVKAEDVADVENFLEENEVHYEVLISNVRNALESQFDSHTRASGHSYTKYNKWETIEAWIQQVATDNPDLVTQSVIGTTFEGRNMYVLKIGKTRPNKPAIFIDCGFHAREWISPAFCQWFVREAVRTYNQEIHMKQLLDELDFYVLPVVNIDGYVYTWTKDRMWRKTRSTMAGSSCLGVRPNRNFNAGWCEVGASRSPCSETYCGPAPESEKETKALADFIRNNLSTIKAYLTIHSYSQMMLYPYSYDYKLPENYEELNALVKGAAKELATLHGTKYTYGPGATTIYPAAGGSDDWSYDQGIKYSFTFELRDTGFFGFLLPESQIRQTCEETMLAVKYIANYVREHLY
What are the official names of this protein?
Carboxypeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted. Zymogen granule lumen.
Protein: SMY2_YEAST
Sequence: MIAPDSQRLFGSFDEQFKDLKLDSVDTENNNTHGVSTILDSSPASVNNNTNGAVAASVNTVPGSTFRSNTPLLGGRHPLSRTSSLIDSIGIQRAASPFSSMKEPFIPQSSGVMSSSFWHGDHPESRVSTPVQQHPLLQRNESSSSFSYAANLGVNLSTHSLAVDITPLSTPTAAQSHVNLFPSSDIPPNMSMNGMSQLPAPVSVESSWRYIDTQGQIHGPFTTQMMSQWYIGGYFASTLQISRLGSTPETLGINDIFITLGELMTKLEKYDTDPFTTFDKLHVQTTSSDSINLNLAPYASGVAATGTIKATENDIFKPLTHDNIWDMDGGTTSKGVDIKLASATTISQTDESHKQEYKSTTMLEKGKKEKSESVAKALLDEQEKRNRELKRKEEARLSKKQKQKEDDLLKKQKEQKEQKEKEALEAEKQKKSEKTKKDTQTQTEGFKTSKDLPSLNSSSANPAPWASKVKVNNAIETSIKNGVSSTGKKKGEPLGLQQRNSKEEKQKEELKSVLNWANKSSLPSNQTIDIKSQFQKSPKGMKESSPLKELEDPNFIEEQKKLWEKVQSSSKQVKSTSSASTTTSSWTTVTSKGKAPIGTVVSPYSKTNTSLNSSLTAKTSTTSTTTTFASMNNVSPRQEFIKWCKSQMKLNSGITNNNVLELLLSLPTGPESKELIQETIYANSDVMDGRRFATEFIKRRVACEKQGDDPLSWNEALALSGNDDDGWEFQVVSKKKGRKH
What is the function of this protein?
Suppressor of the MYO2 gene.
What are the official names of this protein?
Protein SMY2, Suppressor of MYO2-66 protein.
What is the protein family that this protein belongs to?
Belongs to the SMY2/mpd2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_EDWI9
Sequence: MKIVVDENMPYAEALFGRLGEVVAVRGRPLPAAALVGADALMVRSVTTVNQALLAGQRVRFVGTATAGTDHVDTAWLAQAGIGFSAAPGCNAIAVVEYVFSALMLLAERDGFALRDKTVGIVGVGNVGSRLQRRLTALGIRTLLCDPPRADRGDDEQFHSLADLQREADIITFHTPLNKSGPYRTLHLADADFLRGLPPGRILINAGRGAVVDNAALLQALEAGQDLRVVLDVWEPEPMLSLPLLARVDIATPHIAGYSLEGKARGTTQVFEAFSTFLGQPQSVVLPSLLPPPPVASVRIHGHPDQAMLKRLMHLVYDVRRDDVPLRRVAAQEGEFDRLRKHYPARREWSSLQVLCDDCTSASLLTALGFDARVA
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDH5_DECAR
Sequence: MKKIRCALIGSGNIGTDLIYKIQRSPVLEPVWMVGIDPESEGLARAREMGLKTTAAGVDGLLPHVLEDNIQIAFDATSAYVHAENSRKLNELGVMMIDLTPAAIGPLCVPPVNLKEHTEKLEMNVNMISCAGQATIPIVHAISRIQSVSYGEIVASLASKSIGPGTRANLDEFTYTTSNAIEIVGGARKGKALAIINPADPPMMMRNTISCLTDEEPDEPRIIESVLAMIKEVQKYVPGYRLVNGPLFDGKRVTVFMEVAGLGDYLPKYAGNLDIMTAAATRTAEMFAEEILAGTIQLKPVEMAV
What are the official names of this protein?
Acetaldehyde dehydrogenase 5, Acetaldehyde dehydrogenase [acetylating] 5.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: MSH3_DEBHA
Sequence: MAPETKGQRSISHFFKSQSSSQKLNKDDTEYSGNIIDLTNGDEKVSSRLANFEHKPNKSSKSPNELDTSKRKSSKDNEHVDGDPEPVKKKPRTSQSLSRSKSKPQSVGSNSKKLTPLEKQFVEMKQSNLDKILAIQVGYKFKFFGEDAVIASKILSIMLIPGNIKLDEYQHDRFAYCSIPDNRLHIHLKRLLNQGLKVGVAKQTETAAIKSIDSTNKSGLFEREITGVYTKATYMGDELLTGDPNINRTSITDDEMGDYIFCIDESHSKDIGMIAIQPITGDIIYDTFNDNVTRDELETRLVYLNPSEILVINNSTEISKETIKMINIVNNKVNIIHRPRRQQTDYTNEIYNFFNTIDEGKYKDLGEHYLLKFPNNIQSCMIELIKYLEEFKLSNIFTIISNVSCFSNSKTCLVLPSSTVQALEIFQNMTDPNSNKGSLIWLLNHTRTRMGNRLLVKWISKPLIDKAQIEERLQGIEDLTFKFNHFIDSLKNQLDKIGKASIDLEKNLIKVHYSSTYQLDKISRKEVYLLLKCFDDILSMIKQFGKPTNNILESIHSPLLLRIFDELMQLAKEDTVRCLLDMISADALDDSNLNDQKIKFFNLNYFKDQQIISQLSEISNVESLLNDELIEIRKMLKRPQLNYITSSKETYLVEVRNGKMVDSLPKDWIKINGTKTVSRFRSPEITRLHKQLQYHNDMLIRNCDKAFNAYLFKIDNNYEFFSKIIRNLSTFDCLLSLSAVSSINSNYARPKIVEDKQIIQMKNSRNPIIENLSVNYSNYISNDINISYDEDRVLIITGPNMGGKSTYVKQVALLVIMAQIGSYIPCDEATVGIFDSIFIRMGARDNILQNQSTFMIEMLECSHILKNMTSNSLIILDEIGRGTGTNDGIAIAYSILNYLIEEPRKPLTLFITHFPSLHVLEDKFKGIATNYHMGFHEVSKSNQEFPEVVFLYNLVRGVVGNSYGLNVAKLAGIPNSIINNAYTKSTEIRDAIESDWPKKLIKMIKSLREQNDARVELLEIEQLCNNID
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair.  MSH3 provides substrate-binding and substrate specificity to the complex.  When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs.  Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication.  After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MSH3, MutS protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MSH3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPAT_AGARV
Sequence: MFQINDNFQKLPGSYLFSTIAKKVAAYQEANPDKEIIRLGIGDVTQPLAPAIIDALHKAVDEMGNAATFHGYAPDLGYEFLRKAISDNDYKARGCDISADEIFVSDGAKSDSANIQELFSANSRIAVTDPVYPVYVDSNVMAGRTGTYDAQTETWSNVIYMPSTADNGFVPELPKEVPDMIYLCLPNNPTGTTLKKEQLQVWVDYANKNGSVIIFDAAYEAYISEADVPHSIYECNGAKTCAIELRSFSKNAGFTGVRLGFTVVPKELKCGDVSLHAMWARRHGTKFNGAPYIVQRAGEAVYSDAGKAQLKDQVAYYMNNAKTIKTGLAEAGFTVYGGVNAPYIWLKTPDQMTSWEFFDYLLENANVVGTPGSGFGPSGEGYFRLTAFGNYENTVKALERIKAL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: DGTP_KLEP3
Sequence: MAKIDFRNKINWRRRFRSPPRVETERDILRIFESDRGRIVNSPAIRRLQQKTQVFPLERNAAVRTRLTHSLEVQQVGRYIAKEVLSRLKEQKLLEEYGLEELTGPFESVVEMACLMHDIGNPPFGHFGEAAINDWFRQRLAPGDALGQPLTDDRCEVQALRLHEGETALNALRRKVRQDLCSFEGNAQGIRLVHTLMRMNLTWAQVGCILKYTRPAWWFEATPASHSYLMKKPGYYLAEEEYVARLRKELDLAPYNRFPLTWIMEAADDISYCVADLEDAVEKRIFSAEQLYQHLYDAWGNHEKGSLFSQVVENAWEKSRANYLRQSAEDQFFMYLRVNTLNKLVPYAARRFIDNLPAIFTGDFNHALLEDDSDCSQLLELYKNVAMKQVFSHPDVEQLELQGYRVISGLLDIYQPLLKLSLEDFSELVAQERVRRLPIASRLYQKLSTRHRLAYVEAVNKLVRTAPEFALMEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVE
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: EIF3B_TOBAC
Sequence: MADVTSMGEITAIAARIGVDLSQIDLDSIHLPPGEDCGIPSDDDDLMEEDPLEFDAGFGNILVVDNLPVVPKEKFEKLEGVVRKIYSQLGVIKEDGLWMPVDPETHKTLGYCFIEYNTPQEAELSKEKTHGYKLDRSHIFAVNMFDDIERFLKVPDEWAPPEIKPYVPGENLQQWLTDEKARDQFVIRAGNDTEVLWNDARQLKPELVYKRSFWTESFVQWSPLGTYLATVHRQGGAIWGGATTSNRLMRYAHPQVKLIDFSLAERYLVTYSSHEPSNPRDSHAVVLNISDVRTGKVMRDFQGSADEFAVGGTGGVTGVSWPVFRWSGGKQDKYFARIGKNVISVYETETFSLIDKKSIKVENVMDFSWSPADPILALFVPECGNQPARVSLVQIPSKEELRQKNLFSVSDCKMYWQSNGDYLAVKVDRYTKTKKSTYTGFELFRIKERDIPIEVLELDNTNDKIPAFGWGPEGSPICCYPSVTTPRPDIRFYSVPVWALTPGLVSKLTTLKGKQANALYWSPGGRFLILTGLKGFNGQLEFFDVDELETMASAEHFMATDVEWDPTGRYVATSVTSVHEMENGFNIWSFNGKLLYRILKDHFFQYLWRPRPPSFLSKEKEEEIAKNLKRYSKKYEAEDQDVSLQLSEQDREKRKKLKEEWEAWINEWKRLHEEEKMERQKLRDGEASDEEEEYEAKEVEVEEIINVTEEIIPFEESQQ
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, eIF-3-eta, eIF3 p110.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLHD1_RAT
Sequence: MFTSKSNSVSPSPSLEQADADALDISTKVQLYGVLWKRPFGRSSAKWSRRFFIIKESFLLYYSESERKSFETNKYFNIHPKGVIPLGGCLVEAREEPSMPYAMKISHQDFHGNVLLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLMEETEELCLQREQREELERLNQVLEAEKQQFEEVVQELKVEQEQIKRELELTARCLKGVEQEKKELRHLTESLQHTLEELSIEKKKTLEMLEEDKNQPQPLTNQSEQPPATDGLHSNLRQIEERMQELLAEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTAEKQQAEQELKAEVKVRMDLERRLREAEAALRSLEQGLNSKVRNKEKEERMRADVSHLKRFFEECIRNAELEAKMPVIMKNSVYIHKAATRRIKSCRFHRRRSSTSWNDMKPSQSFMTSQLEANNIEELKEVAKRLSRDQRFRESIYHIMATQPGASALPRGGK
What are the official names of this protein?
Pleckstrin homology domain-containing family D member 1, PH domain-containing family D member 1.
What is the protein family that this protein belongs to?
Belongs to the PLEKHD1 family.
Protein: SPKE_SYNY3
Sequence: MTPSLSLGQRLDDRYLIQLHLGQNSLGQQYLAQDTHRFDEPCTITVLTAPPGDKAGNLFKQQAEILYALDHPQIANFREFFALGSELYLVQDFIEGQSYFDLLKDRRLQGKAFTELEVRQWCRQLLPVLHYLHIQKICHGQISPSSIMRRTVDGLPVLVDFTHSQYYSGTPGEDRRDLHGLGLGAIALLTGEVNPNPPWENLLSSVALSQEFRQLLLKLLAWPPLVDWPTLTDNLNNLPQHFLPTVAEFNLTSTIPEQTDNGVGKSSTGEPPFPTVHQSPESSSSAKVKNMVRVDGLKGLVKKSFILLGLMAIAMALGWGAGQLWLDNQQRAALEKLAQEEPGDDVPEKTDLEIKNEIRARRLNLGISPQRFQTLMDDGLAFQLGIDPQQRLEKNPNTNGAPLSLGSPEQQMAMTITVLDALESLSREATRDFAQNNSGDRRRWIPRVNQLRLSSRSFYDLVNARFHHYLPMVSPALLGEPEFEQRPLAQVWNAMAFDSLASLEDESHYQRLSFDDTNQLNLNGTLEPGEGYAYAVTIPPTEEFSLQLTAPPTARISFYPPTGPEVILQNSAMHRWSGPTDQAGYYELVITSVAEEPIAFELELSIIPASAQPF
What is the function of this protein?
Lacks protein kinase activity.
What are the official names of this protein?
Serine/threonine-protein kinase-like protein E.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.