PharMolix/UniProtQA huggingface dataset:
Protein: PODN_MOUSE
Sequence: MAGSRGLPLLLLVLQLFLGPVLPVRAPVFGRSDTPTLSPEENEFVEEENQPVLVLSSEEPEPGPATVDCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLQRLETLNLQNNRLTSRGLPEEAFEHLTSLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDHMFNGSSNVEILILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSNLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIQSVEADVLTPIRNLEYLLLHSNQLQAKGIHPLAFQGLKKLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQMHRDAFRKLRLLRSLDLSGNRLQTLPPGLPKNVHVLKVKRNELAALARGALAGMAQLRELYLTGNRLRSRALGPRAWVDLAGLQLLDIAGNQLTEVPEGLPPSLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVESAFRRLKHLQVLDIEGNFEFGNGSKDKDEEEEEEEEEEDEEEETR
What is the function of this protein?
Negatively regulates cell proliferation and cell migration, especially in smooth muscle cells.
What are the official names of this protein?
Podocan.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class V subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RL27_BORA1
Sequence: MAQKKGGGSTRNGRDSESKRLGVKVYGGQEILAGSIIVRQRGTRFHPGVNVGVGKDHTLFALADGKVKFGTKGALNKATVWVEAAN
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: PIP23_MAIZE
Sequence: MAKQDIEASGPEAGEFSAKDYTDPPPAPLIDADELTKWSLYRAVIAEFIATLLFLYITVATVIGYKHQTDAAASGPDAACGGVGILGIAWAFGGMIFILVYCTAGISGGHINPAVTFGLFLARKVSLVRALLYIIAQCLGAICGVGLVKGFQSAYYVRYGGGANELSDGYSKGTGLAAEIIGTFVLVYTVFSATDPKRSARDSHVPVLAPLPIGFAVFMVHLATIPITGTGINPARSLGAAVIYNKDKAWDDQWIFWVGPLIGAAIAAAYHQYVLRASATKLGSYRSNA
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Aquaporin PIP2-3, Plasma membrane intrinsic protein 2-3, ZmPIP2-3, ZmPIP2;3.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTL_PELPD
Sequence: MSQRIAILPEIITNKIAAGEVVERPASVIKELIENSLDAGATDISVEIAAGGRRLIRITDNGHGMSREDALLSLERHATSKIRSDNDLDGIHTLGFRGEALPSVASVSRLRLSSRETDSPEGTEIIVEGGKVRDVRACGMAPGTVISVEQIFFNTPARLKFLRSAETEAGHVGDCLTRMAISRPDVAFSCSSDGRDLLRVQRGDLLRRLSQALGKGTAASLHELHLSRDGIDISGYISSPAACRSTTSAMFTYINGRFIRDKVIQHAIMQAYRGVMDRGRYPVVALFIQLPPAEVDVNVHPTKHEVRFRRQSLVHDTLQSALEELLKRSPWLPRPQTPVQPAAVGAPSISQAYRERVAAAAQASLAMARKPDPPRFHETARPQPDPRHTPGTESVSVREAPTPFLPREPAADPQGYFSALRIIGQFHDEYILCQSGDQLVIIDQHAASERVAFQKLRHQFDTDGVESQRLLFPETLELSFSEADTARRFGNELARIGFELEPFGGNTVIVSAIPRLAIARDASGLIRDLLAELTQLGASSAFLDSRDALLSRIACHSVVRGVHRLEERQIRELLHGMDGTDFAASCPHGRPVSHVITLGELERIFKRT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: APT_SHIF8
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISENYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_BURCH
Sequence: MSKRRVVVGMSGGVDSSVTAWLLKEQGYDVVGLFMKNWEDDDDGEYCSTRQDWIDVVSVADLIGIDVEAVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLDAEMIATGHYARVRERDGRFELLKAFDHTKDQSYFLHRLNQAQLSKTMFPLGEIPKTKVREIAAQIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTKPGPMKTPDGKVVGEHIGLAFYTFGQRKGIGLGGSKSGSGEPWFVAAKDIASNTLYVVQGHDHPWLLSRELVAGNVSWVAGEPPADGFACGAKTRYRQADAACVFGGAATGAAAAGPAGEVRFSLAFDDAQWAVTPGQSAVLYDGEICLGGGIIESAATGQPGQATSAGHAPALAEAR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_MYCA1
Sequence: MSSPGDTAVLVLAAGPGTRMRSDTPKVLHTLGGRSMLSHLLHAIAKVAPQHLAVVLGHDHERIAPLIADWADDLGRPIDVALQERPRGTGDAVRCGLSALPDDYAGVLVVTSGDTPLLDADTVADLIAGHTATRAAVTVLTTTLSDPSGYGRILRTQDNEVTAIVEHADATESQREIREVNAGVYAFDTAALRSALNRLSADNAQQELYLTDVIAILRGDGLPIRARHVDDSALVAGVNNRVQLAQLGAELNRRIVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGHCVVGPDTTLTDVSVGDGASVVRTHGTGSSVGAGATVGPFAYLRPGTVLGDDGKLGAFVETKNATIGTGTKVPHLTYVGDADIGEHSNIGASSVFVNYDGESKRRTTVGSHVRTGSDTMFVAPVTVGDGAYTGAGTVVREDVPPGALAVSAGPQRNIEGWVRRKRPGSAAARAAEAAEKAAGGRPAGEAE
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_VIBC3
Sequence: MSGNNPSLSYKDAGVDIDAGNALVERIKGAVKRTRRPEVMGGLGGFGALCELPTKYKHPVLVSGTDGVGTKLRLALDMKKHDTIGIDLVAMCVNDLIVQGAEPLFFLDYYATGKLDVDTAAEVISGIADGCLQAGCALIGGETAEMPGMYEGEDYDVAGFCVGVVEKEEIIDGSKVQVGDALIAVGSSGPHSNGYSLVRKILEVSKADKNERLAGKTIGEHLLAPTKIYIKSGLKLIAEHDIHAISHITGGGFWENIPRVLPEGTKAVIDGKSWEWPVIFQWLQEKGNVTTHEMYRTFNCGVGLIIALPKDQANAAVALLQAEGETAWVIGEIAAANSNEAQVEIN
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_RIPO1
Sequence: MSLSATQKQEVITSYQVHETDTGSADLQVALLTTRISQLTGHLQQNPKDHASRRGLLKMIGRRRRLLSYINSKDSQRYQDLIKRLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: LHA3_HALHL
Sequence: MNQARIWLVVKPSVGLPLLLGVVLLIALLVHGAILTNTSWYPTYFEGNW
What is the function of this protein?
Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.
What are the official names of this protein?
Light-harvesting protein B800/850/890 alpha-3 chain, Antenna pigment protein alpha-3 chain, EHA-alpha-3.
What is the protein family that this protein belongs to?
Belongs to the antenna complex alpha subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: POTA_LACLS
Sequence: MSKTIIEFKNVSKTYADTDTTVLKDISFELEEGKFYTLLGASGSGKSTILNIIAGLLDATDGDVILDDKRINDLPANKRNVHTIFQSYALFPNMNVFDNVAFALKIKGVDKKEIAKRVSESLKLVRLDGFEKRSITKLSGGQKQRVAIARAIIDRPKVLLLDESLSALDMKLRKDMQYELRELQQSLGITFIFVTHDQEEALAMSDWVFIMNEGEIVQSGTPTDIYDEPINHFVADFIGESNILNGKMIEDYLVEFNGQKFEAVDGGMRKNEPIEVVIRPEDIWFTLPNEGKFNVKVDTQLFRGVHYEIVAYDEFNNEWIIHSTHKAIVGETVGLDFDPEAIHIMRLNESEEEFDARIEEYVEEEETVGLAKAVEEENAEEEAAIQEAVKEALENTMELTELAETVNEILQKQENETENSESGDHK
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PES1_CAEEL
Sequence: MTSSIKSDAPQFLLDLDNCSSLPPTPPKTASPGNSKMKGFNISDLCLDLDSSTSSSCSVSPASSFHTRSESVGQQQSGRNSPVSSSTESPTKRPKYSYNALIAMAIQSSPFKSLRVSEIYKYISSNFSYYKNQKPLQWQNSVRHNLSLHKEFRKVRTLDGKGSYWAMTADLGTDVYISNNCGKLRRQKSKVAKFPPMQQHFPIPQLPTQNIHQLCMQNPQILATLLQNMYLQNMQNLQNIPMVPGFPIIPVPINPTSFHFPKSS
What is the function of this protein?
Transcription factor (By similarity).  Plays a role in embryogenesis and later development, perhaps acting redundantly with forkhead protein fkh-2 (PubMed:11044397).
What are the official names of this protein?
Forkhead box protein pes-1, Pattern expression site 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: EFP_ACTSZ
Sequence: MASYTTTDFKPGLKFMQDGEPCVIIENEFVKPGKGQAFTRTRIRKLISGKVLDVNFKSGTSVEAADVMDLNLNYSYKDEAFWYFMHPETFEQYSADAKAVGEAEKWLLDQAECIVTLWNGSPISVTPPNFVELEVVDTDPGLKGDTAGTGGKPATLSTGAVVRVPLFIQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSG_SALCH
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVGLRDKLNWFSNY
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: KAD_HELMI
Sequence: MNVLLMGPPGAGKGTQAEMLVSRFAIPHISTGDMFRAAIKNETELGRKAKAFMDAGQLVPDEVTIGIVRERLAQDDCRQGFLLDGFPRTVPQADALEETLKELGLELDAVIDIHVPRERLIERLTGRRICRQCGATYHVLFNPPPTEGLCGKCGGELYQRSDDSRETAENRLDVYTRQTQPLIEYYEAKGRYKRIDGEQDMAAVFKDICAALGRDAE
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_LISIN
Sequence: MPEQIDGNKLDLEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGHVGFGTGKAQEVPDAIRKAVEDAKKNMVFVPTVDTTIPHTVVGHFGGGEILLKPASAGSGVTAGGPVRAVLELAGVADVSSKSLGSNTPINMVRATIDGIKQLKNAEDVAKLRGKTVEELLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: GSPG_XANCP
Sequence: MIKRSITRSPSRAGQAGMSLLEIIIVIVLIGAVLTLVGSRVLGGADRGKANLAKSQIQTLAGKIENFQLDTGKLPSKLDDLVTQPGGSSGWLGPYAKPVELNDPWGHTIEYRVPGDGQAFDLISLGKDGRPGGSSYDSDIKYQ
What is the function of this protein?
Core component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm (PubMed:15590656, PubMed:16078004).  Pseudopilin (pilin-like) protein that polymerizes to form the pseudopilus (PubMed:11931643).  Further polymerization triggers pseudopilus growth (PubMed:11931643).
What are the official names of this protein?
Type II secretion system core protein G, T2SS core protein G, General secretion pathway protein G.
What is the protein family that this protein belongs to?
Belongs to the GSP G family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GRPE_CHLTR
Sequence: MTETPNTSSEEIQTSEPSPDNELQVLQQENANLKAELQEQNDRYLMALAEAENSRKRLQKERTEMMQYAVENALMDFLPPIESMEKALGFASQTSEEVKNWAIGFQMILQQFKQIFEEKGVVEYSSKGELFNPYLHEAVEIEETTTIPEGTILEEFTKGYKIGDRPIRVAKVKVAKLPAKGNSDSNEEKE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_OSTTA
Sequence: MIKAAATLKSLQYRQNSLTDCYGRLSFGPVNPGQGLTIGNTLRRILLNDLPGIGVIGAEINGVQSEFSTLPGIRESVIEIFLNLRELIFTPTATCAQKVKQTKPFVYAKLNSELKIDNFPYVVTAKDLHIPEYEFVDPNQQIATILSPTAAENFKLTLLIGQGRGYQSWKKLPGVPQLMDQRFFEQFDSTQTNSKSVTFPIDAIFMPIRQVNFTVQEHSVDGEYIYFEVWTNGSINPFDAVKSAAKVGMKLMTACLTTLQDQQVYLDESKLPETPNFVQVNYNKMESESNFDQIFIEQLELSLRAYNCLKRANILTLADLSQQSFRDLMKLRNFGQKSADEVRAALSTYGIELKED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RTK1_YEAST
Sequence: MVKETPLHSSSSTSLSSLFRPTKLKNLSAKIFNGGGNQSYSKTDDVSRSSSRSSKKNTDSDQEDQIKYNKPNDRRSTIGKSPQGNGALSKESHVVASSTLTGISPTSAKKAPIDYSPSRPLPNNHNPVRTGHTVPHLPHSIHNPINYIHQGSKDAFHHPHPVRSTAHSNISTVSSAKSDTPSSNLSYQAHMHPVEILQKQIEDKHFMDSQASTPGSVELQHNSSSGSDDTSSRKKKSLRLTRFFKKIHNDYHDNHHHHHHHNRGSTPTKPKLNLNTNENIVESNGKALYETDNPVELLEKYGIPGRKLGEGASGSVSVVERTDGKLFACKMFRKPHLNNEGTNQSQLANYSKKVTTEFCIGSTLHHENIVETLDMLTEGDTYLLVMEYAPYDFFNLVMSNLMTQDEVNCYFKQLCHGVNYLHSMGLAHRDLKLDNCVVTKDGILKLIDFGSAVVFQYPYEDTIVKSHGIVGSDPYLAPELLKQTSYDPRVADVWSIAIIFYCMVLKRFPWKAPKKSFNSFRLFTEEPEDEDDIVRGPNKILRLLPRHSRTIIGRMLALEPKQRVLMNDVVKDDWLVSVPSCEVDPTSGDLVEKPKNHKHHLVTEEELNELTKQHGNKDSN
What is the function of this protein?
Probable serine/threonine-protein kinase that may be involved in ribosome biogenesis.
What are the official names of this protein?
Probable serine/threonine-protein kinase RTK1, Ribosome biogenesis and tRNA synthetase-associated kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: NCPP_OCEIH
Sequence: MQIQVGSQNPTKIQAVKEMFPNIDVIGVQAESGVSAQPFSDEETKLGAITRAKYCAMNNPYTIGVGLEGGVMYIDNELYLCNWGALVTPENDIITASGARIKIPNDVEEGLLKNIELGELMDTYAEKKDVSKKEGAIGIFTNQLITRKEMFRHVVTLLKGQWMLLNSNNH
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Probable inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: PYRE_BUCAT
Sequence: MDWKKEFIDFSFKKKVLKFGVFQLKSGRISPYFFNSGLLSTGIDIIKIGLFYARSIIDSKNKFDVLFGPAYKGIPIAVATSIALKNHYNLNVPYSFNRKEYKEHGEKGDLIGSTIYKKRVIILDDVITSGTAIHHSIKIIEKQEASISSIFVLLDRKEKGIRKLSTINHFRNQKSYKIISIITIDDLIEYVLEDKKLKEHIPQLIKYREKYGI
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: CHED_VIBCM
Sequence: MLVVAVRFSIIWDILFMSDSKLATKRKLKQEEAKGQYYRFNHPSDHRHWVKVMPGGVYATSDQEIIHTGLGSCVSACAWDIEMKVGGMNHFLLPFNNQFESQHWHPQALLSDSSRYGCYAMEVLINRLLSMGAERERLKFKLFGGAHLMGYQSLVGEKNVEFVLEYAKREKLNVVAQDLGGAQPRKLLFDPQTGQAWVKRIGFSSAHAIKQDEELYQHSIDKQIPSDDVELFQ
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: TRPB_SHEB5
Sequence: MSKLKLNPYFGEYGGMYVPQILVPALKQLETAFVEAQEDDDFKAEFTDLLKNYAGRPTALTLTRNLSPNPMVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSGSYEKAHYLLGTAAGPHPFPTIVREFQRIIGEETKKQMLEREGRLPDAVIACVGGGSNAIGMFADFIDEPSVELIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQNSEGQIEESYSISAGLDFPSVGPQHAHLNATGRARYESATDDEALEAFQQLARCEGIIPALESAHAIAYAVKMARECTKETILVVNLSGRGDKDIFTVSDILNGKEV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GRPE_SHIFL
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDP_ECOSE
Sequence: MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGTRKRTHLASNLAEFLNQLKPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: SMRCD_CAEEL
Sequence: MSTTSDFQTGERVRVAHQGNPQSSSLQADMDAKKALLSQNLNNGHLTARPPRTTGPGIKYGEKKPKKQKGSDDDDEDYVDETMPSEDEEDFDNNEEDEDDDDYEEEGPRKRKAPSKKKLVYPRENYRREDSETPEPEMKRIRTLSDSSDDEWMTKPRLNGSESPIGNVMRTQMAKRSAASKRKIVIDDESEDDFINDEEISEKGSGKGSEKEESEGSGKDSETEEVTMKQGQSLKAAMAKAQKEQKKKAESDEDWEEDEDDMNADGDETPSDDSDIEERRAKRGETKNQKECREFFNKAKKEDLLQQARINDKIADFVLANRPFEIYGAMVAKMKGVTRGTNAIEAYMEFLEKRGILSRILDDCKDHAHTVTKDFERCTEGPLQLPLLKEGCTLHDYQLIGVKWLIMMYNKDLNAILGDEMGLGKTIQIVAFLSYLKQIGKTGPHLIVVPSSTIENWIGEFHKWCPSIQLLTYYGSQDERKHLRHRVKKQKDHIDVILTTYNMVTSKSDDKKFFKNFSLNYVIYDEGHMLKNCDSERYRGLMKVKGKKKILLTGTPLQNNLIELISLMYFVLSKVFNKYCEDITHLLQHFKQLGPALDTKNKALYQQDRIEEAKAILQPYILRRLKNQVLGSLPSKSEQIIEVEMKKPQKQLYDNIVEALQQSEESGDSYGSLMRLRQAANHPLLRRSEYTDQKLDKIAKMLCLREKAYADKKWQHVSEDLAWLSDIKIHQLCERFRCTSKFLLNEQLALKSGKCEQLDVMLPEIQKKGDKVLIFSQFTSMLDILEVYLNIRGYSYKRLDGQTPVLDRQEMINEFNLSKDLFVFLLSTRAGGLGINLTSANHIIIHDIDFNPYNDKQAEDRCHRMGQEKPVHVTRLVSKGTVEVGMLALAKKKLQLEKQVTDGVKGQLDEDALRELKEEEGGEQCGGRDLSKLLSSAISGRYDDVEDDSGDSKNGIDAEEAAKKEDEAVKEPVEKEQQKEEESQPSTSA
What is the function of this protein?
DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is both required for DNA repair and heterochromatin organization.  Promotes DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs (By similarity).
What are the official names of this protein?
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS4_RICB8
Sequence: MTKIVRSKYKASRRLGVSLWGDGKDAFNTRNYRPGQHGRNTMVKTSDYGLHLKAKQRIKCHYGRITEKQFRNIFGFAQKMKGNTGENFIGLLESRLDSIVYRMNIAPTIFSSRQLISHGHIKVNGKKADIASMRLKEGDVIEIKEASRQMGIIQESVSKQGQTTPDYVSFDVDSLSGKYLRVPTISDVRYPFTPEVHLVVELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.