PharMolix/UniProtQA huggingface dataset:
Protein: MDTB_PHOLL
Sequence: MQAGSPIPGGGPSRLFILRPVATTLFMAAILLAGIIGYRMLPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQLGQMSGLKQMASQSSGGASVITLQFQLTLPLDVAEQEVQAAINAASNLLPNDLPYPPIYSKVNPADPPILMLAVTSDAMPMTQIQDMVETRIAQKISQVNGVGLVTLAGGQRPAVRVKLNAQAVAAQGLDSETIRTAINNANVNSAKGSLDGPTRSVTLSANDQMKSVNDYRNLIIAYKNGSPVRLQDVATIEQGAENTKLGAWSNNTQAIVINVQRQPGANVIETTDNIRQMLPELISSLPKSVDMKILTDRTTTIRASVKDVQFELLLAIALVVMVIYLFLRNGIATLIPSIAVPLSLIGTFAVMYFCGFSVNNLTLMALTIATGFVVDDAIVVIENISRYIEQGEKPMTAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARILKPESQIKHNRFEQASGRFFEQMIAGYAVWLKRALNHPWITFGIALSTLALTALLYLMIPKGFFPSQDNGLIQGTLEAPQSISFTAMVNKQQQVSSLLLQDPAVENITTFVGVDGSNPTLNNGRLQITLKPLNQRDDRIVDIIPRLQEKVAAIPGIKLYLQPMQDLTIDTQVTRTQYQFTLQATSLDELSIWVPKLLAELKQRAELVDISSDWQDQGLIAYVKVDRDIASRLGISMAAIDNALYNAFGQRLISTIYTQANQYRIILEHDVTSTPGLAAFDNIRLNGTDGHVVPLRTIATIEQKFGPLAINHLAQFPSATFSFNVAEDASLEQAVNAVRDAAQLINMPKDISTQFQGTTLAFESALGNTLWLIAAAIIAMYIVLGILYESFIHPVTILSTLPTAGVGALLALMMAGHELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGLSPYEAIYQACLLRFRPILMTTMAALLGALPLMLSTGVGAELRRPLGICMVGGLIMSQILTLFTTPVIYLLFDRLAHYRRNRQLSVSNTPSIDHQEPR
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ILVB_ARATH
Sequence: MAAATTTTTTSSSISFSTKPSPSSSKSPLPISRFSLPFSLNPNKSSSSSRRRGIKSSSPSSISAVLNTTTNVTTTPSPTKPTKPETFISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPEDSHLEQIVRLISESKKPVLYVGGGCLNSSDELGRFVELTGIPVASTLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKTPHVSVCGDVKLALQGMNKVLENRAEELKLDFGVWRNELNVQKQKFPLSFKTFGEAIPPQYAIKVLDELTDGKAIISTGVGQHQMWAAQFYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVENLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAARVTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVITEGDGRIKY
What is the function of this protein?
Catalyzes the formation of acetolactate from pyruvate, the first step in valine and isoleucine biosynthesis.
What are the official names of this protein?
Acetolactate synthase, chloroplastic, AtALS, Acetohydroxy-acid synthase, Protein CHLORSULFURON RESISTANT 1.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SAHH_HUMAN
Sequence: MSDKLPYKVADIGLAAWGRKALDIAENEMPGLMRMRERYSASKPLKGARIAGCLHMTVETAVLIETLVTLGAEVQWSSCNIFSTQDHAAAAIAKAGIPVYAWKGETDEEYLWCIEQTLYFKDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEETTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRIILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHFLPKKLDEAVAEAHLGKLNVKLTKLTEKQAQYLGMSCDGPFKPDHYRY
What is the function of this protein?
Catalyzes the hydrolysis of S-adenosyl-L-homocysteine to form adenosine and homocysteine (PubMed:10933798).  Binds copper ions (By similarity).
What are the official names of this protein?
Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: TSAD_STRTD
Sequence: MADRYILAVESSCDETSVAVLKNEKDLLSNIIASQVESHKRFGGVVPEVASRHHVEVVTLCIKDALSEAGIVAEQLDAVAVTYGPGLVGALLVGMAAAKAFAWAHGLPLIPVNHMAGHLMAAREVQELEYPLLALLVSGGHTELVYVSEPGNYKIVGETRDDAVGEAYDKVGRVMGLTYPAGREIDELAHKGKDVYDFPRAMIKEDHLEFSFSGLKSAFINLHHNAEQKGEVLVTEDLCASFQAAVLDILLAKTKKALERYPVKTLVVAGGVAANQGLRERLAEEITDVDVVIPPLRLCGDNAGMIALAAAIECDKKHFADLDLNAKPSLAFAGFEE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y778_HAEDU
Sequence: MKAVEFVENPYGIRLRIFLQPKASRDQIVGLHDNELKVAITAPPVDGAANAYLLKYLSKLFKVPKSSIVLEKGELQRHKQLFVPAPKLLPKEIEQWL
What are the official names of this protein?
UPF0235 protein HD_0778.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: RRP36_VERA1
Sequence: MLKSTARKRKAPSTGPSGLQRRVRARKEEVDSEIDESSNPSENEGSERSSDEDEEDEEPKASRSSKSNLDMASISFGALAKAQASMPKRSKKESAESEESEIDDSGSDSGNESKYRKRGGLAKRSSKHAPTEMSSKRPVSRKREIFQVPKVEARDPRFDPAVNSGGSNFDEAKAKKAYAFLDEYRDSEMAELRMEIRKTKDAAQKERLQTLLQSMQNRKKAAKRKDDEKRILEEHRQREKDLVQQGKQPFYLKKSEQKKRLLTEQFKGMKKKQVNKVIERKRKKVAAKEKMELDQLQRR
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein RRP36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: OTCC_LATSK
Sequence: MTNSVFQGRSLLAEKDFTKSELEYLIDFSLHLKDLKKKGIPHHYLEGKNIALLFEKNSTRTRAAFTTAAIDLGAHPEFLGKNDIQLGKKESVEDTAKVLGSMFDGIEFRALAKVVEDLAKYSGVPVWNGLTDEWHPTQMIADFMTVKENFGKLKGVTLTYVGDGRNNMANSLLVTGSMLGVNIHIVAPDSLQPTQEVRDLAEGYAKETGSKNMITSDVDAGVKGSDVLYTDVWVSMGEEDKFEERVNLLKPYQINMDMVKKTGNENMIIMHCLPAFHDIETEYGKKIDEQFGIQEMEITDEAFRSKYARQFEEAENRMHSIKAIMAATLGNLFIPQA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_PYRAB
Sequence: MRVDLNSDLGESFGRYKLGLDEEVMRYITSANIACGWHAGDPIVMRRTVKLAKENNVQVGAHPGYPDLMGFGRRYMKLTPEEARNYILYQIGALYAFAKAEGVELQHVKPHGALYNAMVKEEELARAVIEGILDFDKNLILVTLSNSRVAEIAEEMGLKVAHEVFADRAYNPDGTLVPRGKPGAVIEDKEEIAERVISMVKDGGVRAINGEWVELRVDTICVHGDNPKALEITSHIRKILEEEGVKVVPLKDFIG
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: GATC_PHEZH
Sequence: MAIDAATVRKVARLARIAEPEEKLEPLAKELSGILNWIEQLNEVDTDGVEPMTTSVETTLPMRDDVVTEGGDPAKVLANAPKAAKNFFVVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: EFP_THEPX
Sequence: MIAAGDFRKGVTIEVDGQVFTVVDFMHVKPGKGAAFVRTKLKNVMTGAVIEKTFSPTEKFEEAVIERREMQYLYNDGELYYFMDTETYEQIPLNYDKVEDAIKYIKENMVVTVKFYKGEAFSVEPPTFVELEVVETEPGFRGDTATGGSKPATVETGAVIQVPLFINVGDKIRIDTRTGEYLERV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_CLOAB
Sequence: MAVQKNKKTRRRKEKKNIEHGCAHIKSTFNNSIVTITDVNGNALSWSSAGGLGFKGSRKSTPFAAQMAAETAAKTAMEHGLKSVDVFVKGPGSGREAAIRSLQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FB54_ARATH
Sequence: MRKGNEEKNYREEEYLQLPLDLIVEILKKLPLKSLVRFRCVSKQFSTIICSLRDFIESVVTRHLAQPGQQLPLLAVFHHCVPETFFTVSSSFSQSLKPAIYNPTTKRSVGLPEIGPPVTGFRKCNCLFGYDPVMDQYKVLSMVFDFRELTQTFHVFTLGQSQSWRRIQGINDGKLFPSAVGICIDGTFEFLRFKRDQDCLFCDNETQHIII
What are the official names of this protein?
Putative F-box protein At1g52490.
Protein: MLTC_PASMU
Sequence: MKKYIIYALIPFLFACGGTKTHRSSQFDEAFAKDTRGLDILTGQFSHNIDRIWGVNELLVASRKDYVKYTDRFYTRSHVSFDEGLITVETQSDLRHLQNAIVHILLMGSDANGIDLFASGDVPISSRPFLVGQVIDHLGGSITNTTTAGNFANYLLQNKLQTRRLSNGHTVQYVVIPMIANHVAVRAQRYLPLVRKMARRYNMDESLILGIMQTESSFNPYAISYANAIGLMQVVPTTAGRDIFKMKGKGGQPSKSYLFDPEKNIDAGTSYLWLLQNKYLDGITNPTSKRFAMISAYNSGAGAVLRVFDQDRDAAIVKINSLYPEQVYRILTTQHPSAQARNYLLKVDQAQKSYRVRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ADRB3_MERUN
Sequence: RVGADAEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRRLLRRELGRFPPEESPRSPSRSPSPVAGGTGEAPDGVPSCGRRPARLLPLREHRALRTLGLIMGIFSLCWLPFFLANVLRALAGPSIVPNGVFIALNWLGYANSAFNPLI
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  Beta-3 is involved in the regulation of lipolysis and thermogenesis.
What are the official names of this protein?
Beta-3 adrenergic receptor, Beta-3 adrenoreceptor, Beta-3 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WLS_DROSI
Sequence: MSGTILENLSGRKLSILVATLLLCQVLCFLLGGLYAPLPAGHVTVLGSLCREDHARQNDTSFLLYSRGAGACIPVTREEVEQDSTKMANELVHVFQMPLPRDLRDLDYSRWQQNLIGVLQVEFGYDSSSELREPPRELQLTIDMRLAYRNKGDPDNGWKLYAHGVEHRYLDCVTSHVGPTETLYSCDMIPLFELGALHHSFYLLNLRFPLDTPSQMNLQFGHMHDLTLTAIHQNGGFTQIWLLLKTMLFPFVVGIMIWFWRRVHLLQRSPALLEYMLIYLGAALTFLNLPLEYLSLVYEMPYMLLLSDIRQGIFYAMLLTFWLVFAGEHMLIQDAPNKSTIRSRYWKHLSAVVVGCISLFVFDICERGVQLRNPFYSIWTTPLGAKVAMTFIVLAGVSAAIYFLFLCYMIWKVFRNIGDKRTSLPSMSQARRLHYEGLIYRFKFLMLATLVCAALTVAGFIMGQMAEGQWDWNDNVAIQPTSAFLTGVYGMWNIYIFALLILYAPSHKQWPTMHHSDETTQSNENIVASAASEEIEFSHLPSDSNPSEISSLTSFTRKVAFD
What is the function of this protein?
A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells.  In non-neuronal cells wls directs wg secretion.  The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26).  In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles.  Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip (By similarity).
What are the official names of this protein?
Protein wntless.
What is the protein family that this protein belongs to?
Belongs to the wntless family.
What are the subcellular locations of this protein?
Presynaptic cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=In non-neuronal cells, wls binds to wg in the Golgi and accompanies it to the plasma membrane where the two proteins dissociate. Wg is secreted and wls is then internalized and returns to the Golgi apparatus in a retromer-dependent manner. Wls and wg colocalize in the Golgi apparatus in wg-producing cells, and reduced expression is seen in non-producing cells. Endoplasmic reticulum expression is unchanged in wg-producing versus non-producing cells. In neuronal cells, wls is localized both pre- and postsynaptically and is transferred trans-synaptically from the pre- to the postsynaptic compartment (By similarity).
Protein: ILVH_MYCTO
Sequence: MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGPRGIGTAK
What is the function of this protein?
Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
What are the official names of this protein?
Putative acetolactate synthase small subunit, Acetohydroxy-acid synthase small subunit, AHAS, ALS.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: CYAS_METMA
Sequence: MGRFTLKCLKCGREYGQEYRLTCDNDDSLLRADYFEKKLELRDQPGIGRFHSWLPVQEELTTEAGPITYKSEALAKELGLSNLYIGFSGYWPEREALIKTCSFKELEAHPTMQLLKESGGKAIVLASAGNTGRAFAYSSSLTGTDAYIVVPDSGVSSIWLPEEPANSIHLISMTPGNDYTDAINLAGRLAKLPGMVPEGGARNVARREGMGTVMLDAAVTIGKMPDHYFQAVGSGTGGMSAWEASLRLRDDGRFGSKLPKLQLAQNLPFVPMYNAWKAGRREIIPDIDMKDAKKQIEETYATVLTNRAPPYSITGGLYDALVDTDGIMYAITREEALEAKALFESLEGIDILEPSAVAAASLLKAVEAGNVEKDDVILLNIAGGGFKRLKEDFTLFQVEPEVTVSSSEVSLDELKI
What is the function of this protein?
Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate.
What are the official names of this protein?
Cysteate synthase, CS, Cya synthase.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family. Cysteate synthase subfamily.
Protein: SYS_STRZJ
Sequence: MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVKVETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTTTLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTGARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTFELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSTAKTYDLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEALRPYMGGAEVIKP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_GEOMG
Sequence: MKIEIAIVLILAAAGLGYFVGNMLRKRISDTLVSKAEELASKIVDDAKREAETITKEAELKAKDEVFQAKAEAERDAKEKRKDLQALEKRLQQKEENLDKKMNLFDQRDADLTKKDQALLNREQGLVQKEERLDGLIAEQREKLESISGLSSTEAKKILMDAMESEAKLDAAKRIKVIEEEARETADKKSKEIMALAIQRYAGEYVAERSVSVVALPSDEMKGRIIGREGRNIRALEAATGIDLIIDDTPEAVILSGFNPVRREVAKIALEKLITDGRIHPGRIEEVVAKAEEEVEQTIKEAGDQAAFDLGVHGIHPEILKLIGRLKYRTSYSQNVYQHSLEVAFLCGIMASELGINVKQAKRAGLLHDLGKAVDHEVEGSHAVIGAELARKYGESPKIVHAIMAHHEDEKPNTVLAVLVQAADALSGARPGARREMMETYVKRLDDLERIATSFVGVNNSFAIQAGREIRVMVSSDEVTDERAVVLAKDIAKKIEAEMTYPGQIKVNVIRETRAIEYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RUVB_PSYWF
Sequence: MENRLINPVERVDDSVDNNIRPSTLAEYIGQPVVREQMEVFIEAARRRNEALDHTLIFGPPGLGKTTLANIIAREMGGNLRSTSGPVLERAGDLAAMLTNLEEGDVLFIDEIHRLSPVIEEILYPAMEDFQLDIMIGEGPAARSIKLDLPPFTLVAATTRAGLLTSPLRDRFGIVQRLEFYNIEDLTTIVSRSARLMNVVMTPEGAVEVARRSRGTPRIANRLLRRVRDYAQVKSNGEVTGEIADSALDMLAVDRRGLDHLDRRYIEMVHARFDNGPAGVEAIAAAMAEDRGTLEDVIEPYLIQQGYVLRTARGRVLTQMAIDQL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GLK_RHILW
Sequence: MPKPNHSTAPLPFPILIGDIGGTNARFSILTDAYAEPKQFPNVRTADFATIDEAIQQGVLDKTAVQPRSAILAVAGPINDDEIPLTNCDWVVRPKTMIEGLGMEDVLVVNDFEAQALAVAALSDENRERIGEATGDMIASRVVLGPGTGLGVGGLVHAQHSWIPVPGEGGHVDLGPRSKRDYQIFPHIETIEGRVSAEQILCGRGLVNLYHAICVVDGIQPTMKDPADITSHALAGSDKAAVETVSLFATYLGRVAGDMAMVFMARGGVYLSGGISQKILPALRRPEFRLAFEDKAPHTALLRTIPTYVVTHPLAALAGLSSYARMPANFGVSTEGRRWRR
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_HELHP
Sequence: MKYPEMTLATLAILKYPNALLRKKSIPVEIFDDNLHNFLDDMYETLIESKGVGLAAIQVGRAERILIINIPREEDKQQYKEDLLEIINPTFLTQEECVEWEEGCLSVPDFYESIKRFDKVSIAYKDRYGNDRILKAQGFLAVAIQHEIDHLNGVLFVDKLPILKRKKFEKELKKLKKESQA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RS15_BARBK
Sequence: MSITAERKQELITEYATKAGDTGSPEVQVAVLSERISNLTNHFKSHKKDNHSRRGLLKMVSQRRRLLDYLKEVNHSRYQVLIEKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DNAE2_XANCB
Sequence: MSWDDAIDGVDRDTPGGRMPRGWTVAARLRAANDDITHAAVADTLPAYAELHCLSDFSFLRGASSAEQLFARAHHCGYSALAITDECSLAGIVRGLEASRATGVRLIVGSEFTLIDCTRFVLLVENAHGYPQLCSVITTGRRAAGKGAYRLGRAEVEAHFRDVVPGVFALWLPGDQPQAEQGAWLQRVFAERAFLAVELHREQDDAARLQALQALAQQLGMSALASGDVHMAQRRDRIVQDTLTAIRHTLPLADCGAHLFRNGERHLRPRRALGNIYPHALLQASVELAQRCTFDLSKVQYTYPRELVPQGHTPASYLRQLTEAGMRERWPEGAPANVVAQIDSELELIAYKGYEAFFLTVQDVVRFARAQHILCQGRGSSANSAVCYALGITAVNPSETRLLMARFLSKERDEPPDIDVDFEHERREEVLQYVYTKYGRERAALAATVICYRGKSAVRDVAKAFGLPPDQIALLANCYGWGNGDTPMEQRIAEAGFDLANPLINKILAVTEHLRDHPRHLSQHVGGFVISDEPLSMLVPVENAAMADRTIIQWDKDDLETMQLLKVDCLALGMLTCIRKTLDLVRGHRGRDYTIATLPGEDAATYKMIQRADTVGVFQIESRAQMAMLPRLKPREFYDLVIEVAIVRPGPIQGDMVHPYLRRRQGYEPVSFPSPGVEEILGRTLGIPLFQEQVMELVIHAGYTDSEADQLRRSMAAWRRGGDMEPHRVRIRELMAGRGYAPEFIDQIFEQIKGFGSYGFPQSHAASFAKLVYASCWLKRHEPAAFACGLLNAQPMGFYSASQIVQDARRGSPERQRVEVLPVDVLHSDWDNILVGGRPWHSDADPGEQPAIRLGLRQVSGLSEKVVERIVAARAQRPFADIGDLCLRAALDEKARLALAEAGALQSMVGNRNAARWAMAGVEARRPLLPGSPAERAVELPAPRAGEEILADYRAVGLSLRQHPMALLRPQMLQRRILGLRELQARRHGSGVHVAGLVTQRQRPATAKGTIFVTLEDEHGMINVIVWSHLAMRRRRALLESRLLAVRGRWERVDGVEHLIAGDLYDLSDLLGEMQLPSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_AZOPC
Sequence: MTLMDGRAIAAQIKLEITKEVQQIVINGEKKPHLAAILVGHDCSSETYVANKVKTCEELGFQSTLIRYESDLIENKLLATVEKLNQDSNIDGFIIQLPLPKHISEQKVIEAIDYKKDVDGFHPVNAGRMAIGLPCFVPATPAGILELLKRYKITTAGKHCVVLGRSNIVGKPIANLLMRKAYPGDCTVTVCHSRTKNILKHCLEADIIIAAMGVPEFLKGNMVKDGVVVIDVGTTRVLSTETDSGFKLRGDVRFKEVAPKCSYISPVPGGVGPMTIISLMRNTLLARKKVIYS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MATK_TYPLA
Sequence: MKQLHVQKYLEKVRSRKQHFLYPLLFKEYIYAFAHDYGLNGSIFYEPTEILGNDNKSSSVLVKRLIIRMYQQNYLINSTNHSNQNRFLGHNNYFYSRFFSQMISESFAVIMEILFSLRLVSSSEKKEIPQFHNLRSIHSIFPFLEDKLSHLNSISDILIPHPIHLEILVQILQCRIQDVPSLHLLRFFLHEYHNWNSLITSKKSIYVFSKENKRLFRLLYNFYVFECEFVFVFLRKQSSYLQLTSFGTFLERIHFYGKIEHLLVVYRNFFNKTLWFFTDPFMHYVRYQGKAILASKGTHLFMKKWKCYLVNFWQYYFHFWSQPHRIHINQLSNYSFHFLGYLSSLLRNPLVVRNQMLENSYLIDTVMTKFDTIXPVDPLIGSLSKAKFXTLLGHPISKPIWTDLSDCDIIDRFGRICRXLSHYYSGSSKKRTLYRIKYILRFSCARTLARXHKSTVRTFMQRLGSVLLEEFFTEEEQVLSLIFPKTTPFSLHGSHRERIWYLDIIRINDLVNH
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.