PharMolix/UniProtQA huggingface dataset:
Protein: PDXK_BORPE
Sequence: MKLAAPNPQALAPLPIDVVSIQSQVVYGQVGNSVAVPVFNGFGLRVAAVPTVVLSNTPHYPSMHGGAVPLDWFEGYLADLGARGALAGVRVVQLGYLGGPAQAEALGRWIAGLVAERPDLRVHIDPVIGDHDSGVYVAPGMVAAYRDHLLSLAQGLTPNGFELECLTGLPTGTMEQTIAAARTLLGGRARWVIVTSAAPATWPPGRVRVAVVTHDDAQVLEHAHVDTAPKGTGDMFGAALTGHRLAGQPVAEAARRAALQVIEALERTREAGCGELLLAGPLR
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: UGL_BURM1
Sequence: MKLLRYGPPGQEKPGILDADGRIRDLSAHVPDLAGDVLSDAGLARLRALDPATLPLVSGEPRIGACVGRVGKFIGIGLNYADHAAEAGMPVPKEPVVFGKWTSSICGPNDGIDIPKGSVKTDWEVELGVVIGAPCKDVDEARALDYVAGYCVVNDVSEREWQIERGGQWDKGKGFDTFGPIGPWLVTRDEVPDPQSLDLWLEVDGHRYQNGNTRTMVFTVAQLIAYLSSCMTLQPGDVITTGTPPGVGMGIKPAPVYLKAGQMVRLGIEGLGEQLQLTRAAR
What are the official names of this protein?
Ureidoglycolate lyase, UGL, Ureidoglycolase, Ureidoglycolatase, Ureidoglycolate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: TOR2A_XENLA
Sequence: MAVRWWIIPMLLLVPGSSGAWEVLSLPFSLYNFYECGFKVDIEALDCDLARNVFGQHLAQELLFKSVKEFIESDNPSKPLVLSLHGWSGTGKTFVSSLLVKHLFKEGSQSRFVHFFSPVLHFPRVQNLEQYKVDLKGWIQGNLTACGRSLFVFEEMDKMHPGLIDAIVPFLGTSWVVYGSNYRKAIFLFISNAGGDDINEVALDFWRQRKDREDIRLHHLESAISKAVFSNPKHGFWQSQIINQHLIDVIVPFLPLRPSHVRQCVRTEMVQQGLEPEEVLVNNITDSFVYFPEDEKVFSSTGCKTVASRINYFV
What are the official names of this protein?
Torsin-2A, Torsin family 2 member A.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: Y669_THEFY
Sequence: MRTRARLADQRRTLGQRGEELAARYLTRHGMRVLQRNWRCRDGEIDILARQDRTLVVVEVKTRAGRRFGTPLEAVDETKRARLRALGYRWARDHGCSARIRVDVVGILVLPGNQWFLRHQRGVA
What are the official names of this protein?
UPF0102 protein Tfu_0669.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: KATG_CAUSK
Sequence: MDGSELVEPTTKCPLKHGVRFHTSFGGRSNRDWWPNQLNLKILHQHAPASNPMPAGFSYAEQVETLDVEALKRDLAALMTDSQDWWPADYGHYGPLFVRMAWHSAGTYRTGDGRGGAGGGQQRFAPLNSWPDNGNLDKARRLIWPIKQKYGARISWADLMILAADVGMETMGFKTFGFGFGREDTWEPEEDVHWGAEDTWLGDARYTGERELDKPLGAVQMGLIYVNPEGPNGKPDPLAAAHDIRETFARMAMNDEETVALIAGGHTFGKAHGAGDAAHVGVEPEAAGIALQGLGWKNSFGSGVGSDAITSGLEGPWTPNPIKWDNGFFDTLFGHEWELTKSPAGAFQWTPKDPEAGPKAPDAHDPSRQVAPMMLTTDLALRLDPNYGPISKRFHENPDQFQDAFARAWFKLTHRDMGPKARYLGPLVPQEELLWQDPLPEPQGPPIDANDIRELKAKVLATGLSVPQLVATAWASASTFRGSDKRGGANGARIRLSPQKDWAVNQPAQLANVLATLEGVQSAFNGGQTDGKTVSLADLIVLAGCAAVEQAAKAAGHDVEVPFTPGRVDASQNQTDVASFGVLEPKADGFRNYLNTDLPLTAEELLVDKAQLLTLSAPEMTVLVGGLRALNANTDQSSHGVFTTRPGSLTNDFFVNLLDMRTVWTATSEDEAQFEGRDRTTGDLKWTATRVDLIFGSNSQLRALAEVFAQSDSQGAFVGAFVAAWTKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RRF_AZOC5
Sequence: MTTAFDIADIKRRMAGAVTSLKQELGGLRTGRASASLLEPITVDAYGANMPLAQVATVSVPEPRLLSVQVWDRGMVNAVEKAIRDSNLGLNPNTEGQTLRIRIPELNEERRKELVKVAHKYAEAARVAVRHVRRDGMDLLKKLEKDSAISSDDMERLSKDVQKATDETISEVDQTLAHKEKEILSV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IELK1_BAURF
Sequence: ASPVLDANGDPLVPGGQYYVLPHIWPGPGGLSFEKTGNQTCPVSVFQLPRLPLEQNNGKPLVFTPVSETDDINEDTAVEIAFAEPPSCAESGKWLIVNDFKEEYWSVGIGGPQDHEGYQTLTGYFKIHKVGSFAYMFSFLPFVR
What is the function of this protein?
Inhibitor of porcine pancreatic elastase with a Ki of 27 nM.  Does not inhibit human neutrophil elastase, bovine trypsin, human plasma kallikrein or porcine pancreatic kallikrein.
What are the official names of this protein?
Kunitz-type elastase inhibitor BrEI.
What is the protein family that this protein belongs to?
Belongs to the leguminous Kunitz-type inhibitor family.
Protein: Y2102_COREF
Sequence: MSIFVENQLLALVAIMGIGLLLGRIRFFGFRLGVAAVLFVGLAFSTIEPDITVPPLIYVVGLALFVYTIGLEAGRDFFRSLRSTGLRNNGLALGAIIATTAIAWVVIKALGLAPATGAGMLTGALTNTPAMAAVVDALPALIDDNPTDAARILELPVVAYSLTYPLGVLVVILTIAVCGGLFKVNHEKEAKNAGVAVQELTGRRVRVTRDDLPAISNIPELLDLEVIVSRVERRGQHDQFIPEEGDRTRLGDILTVVGSDDELERAVGLLGEFVDGHPYSDIDLDYRRIFVSDESMVGVPLAKLRNRIPGMLITRIRRGDTDLIAHPDMTLQLGDLVRVVAPAERIKEATHIFGDSYKRLADFNLVPLVVGLSLGVLVGMMEFPLPGGSALSLGNAGGPLLIALLLGAMGRTGKVVWQIPYSANLALRQLGITMFLAAIGTTAGAGFRSALSDPASLLIIGVGALLTLVISVLVLVIGHKVMRIPFGETAGILAGTQTHPAVLSYISEASRNELPAMGYTSVYPLAMVAKIIAAQVLLFLLI
What are the official names of this protein?
Uncharacterized transporter CE2102.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y507_HAEIN
Sequence: MKENKPVDPYAKYNEQSNIIAKIIFASRWLQVPIYLGLIVTLAIYSYKFIKGLWELVINVNDMDSNTIMLGVLNLIDVVMIANLLVMVTIGGYEIFVSKLRTRNHPDQPEWMSHVNATVLKVKLSMSIIGISSIHMLQTFVNASNMPEKTMMWQLLLHLGFLVSAIALAYTDKILYSTSHKTH
What are the official names of this protein?
UPF0114 protein HI_0507.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PREP_EMENI
Sequence: MLRSYLHLGRHRTPAFRQPLGRLLRPTASILQYAQSRTLASVSSLESLPEVGDQLHGFTVQEKKQVPELHLTAIRLRHDKTHADYLHIAREDKNNVFGIGFKTNPPDATGVPHILEHTTLCGSEKYPIRDPFFKMLPRSLSNFMNAFTSSDHTMYPFATTNQQDFQNLLSVYLDATMHPLLKEEDFRQEGWRLGPEDPRAIQTQEGNLKPEDILFKGVVYNEMKGQMSDANYLYWIRFQESIFPAINNSGGDPQHITDLTHKQLVEFSKKNYNPSNAKIITYGDMPLADHLKQVGGVLNDFSKGAVDTTVKLPIELRGPINVTVPGPIDTFVSEDRQFKTSTSWYMGDITDTVETFSAGILSSLLLDGYGSPMYKALIESGLGSSFTPNTGLDTSGKIPIFSIGVTGVSEEQAPRVKEEIQRVLQETLQRGFNDEKVQGFLHQLELALRHKTANFGLGVIQKTFTSWFNGSDPMKELAWNEVINAFKSRYEKGGYLEALMQKYLINDNCLTFTMVGTPSFNKELDDKEMARKEKKFEQLTQQHGSVEKAVTELAKAELQLLEVQEKAQHADLSCLPSLRVEDISRQKEHKPVRESKVEGTDIVWREAPTNGLTYFQAVNAFADLPDDLRLLLPLFNDAIMRLGTPTRTMEQWEDLIKLKTGGVSTSNFHTTSPTEMGKYTEGLQFSGFALDKNVPDMLEILTALVTETDFTSPSAPAMIQELLRLTTNGALDAVAGTGHRYALNAAAAGLSRSFWAQEQTSGLAQLQATANLLRDAETSPERLAELIEKLRLIQSFAISKTSGLRVRLVCEPASSTQNESVLQRWVTGLPKVPSPTSQPQRFDLSTPSKKAFYDLPYKVYYSGLALPTVPFTHSSSATLSVLSQLLTHNYLHPEIREKGGAYGAGASNGPVKGLFAFTSYRDPNPANTLKVFKNSGVFARDRAWSDREINEAKLGIFQGLDAPVSVDEEGSRYFLNGITHEMDQRWREQVLDVTAKDVNEVAQTFLVDGTRRSVCLLGEKKDWAESEGWEVRKLSMNPNGSNIPSGDAA
What is the function of this protein?
Degrades mitochondrial transit peptides after their cleavage in the intermembrane space or in the matrix, and presequence peptides; clearance of these peptides is required to keep the presequence processing machinery running (By similarity).  Preferentially cleaves the N-terminal side of paired basic amino acid residues (By similarity).  Also degrades other unstructured peptides (By similarity).  May function as an ATP-dependent peptidase as opposed to a metalloendopeptidase (By similarity).
What are the official names of this protein?
Presequence protease, mitochondrial, PreP, Pitrilysin metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. PreP subfamily.
Protein: CPG2_PORGI
Sequence: MKKNFSRIVSIVAFSSLLGGMAFAQPAERGRNPQVRLLSAEQSMSKVQFRMDNLQFTGVQTSKGVAQVPTFTEGVNISEKGTPILPILSRSLAVSETRAMKVEVVSSKFIEKKDVLIAPSKGVISRAENPDQIPYVYGQSYNEDKFFPGEIATLSDPFILRDVRGQVVNFAPLQYNPVTKTLRIYTEIVVAVSETAEAGQNTISLVKNSTFTGFEDIYKSVFMNYEATRYTPVEEKENGRMIVIVPKKYEEDIEDFVDWKNQRGLRTEVKVAEDIASPVTANAIQQFVKQEYEKEGNDLTYVLLVGDHKDIPAKITPGIKSDQVYGQIVGNDHYNEVFIGRFSCESKEDLKTQIDRTIHYERNITTEDKWLGQALCIASAEGGPSADNGESDIQHENIIANLLTQYGYTKIIKCYDPGVTPKNIIDAFNGGISLANYTGHGSETAWGTSHFGTTHVKQLTNSNQLPFIFDVACVNGDFLYNVPCFAEALMRAQKDGKPTGTVAIIASTINQSWASPMRGQDEMNEILCEKHPNNIKRTFGGVTMNGMFAMVEKYKKDGEKMLDTWTVFGDPSLLVRTLVPTKMQVTAPANISASAQTFEVACDYNGAIATLSDDGDMVGTAIVKDGKAIIKLNESIADETNLTLTVVGYNKVTVIKDVKVEGTSIADVANDKPYTVAVSGKTITVESPAAGLTIFDMNGRRVATAKNRMVFEAQNGVYAVRIATEGKTYTEKVIVK
What is the function of this protein?
Thiol protease.  Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA (By similarity).  Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms (Probable).
What are the official names of this protein?
Gingipain R2, Arg-gingipain, Gingipain 2, RGP-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C25 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YAAI_SALG2
Sequence: MRSVLTISAGLLFGLALSSVAHANDHKILGVIAMPRNETNDLALKIPVCRIVKRIQLTADHGDIELSGASVYFKTARSASQSLNVPSSIKEGQTTGWININSDNDNKRCVSKITFSGHTVNSSDMARLKVIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: ATPA_GRABC
Sequence: MDIRPAEISEILKSQIASFDSEANVAETGQVLSVGDGIARVYGLQNVMAGELVEFPSAGLKGMALNLENDNVGVVIFGDDRQIREGDTVARTREIVDVPVGRGLLGRVVDALGNPIDGKGPLTDVTRTRVEVKAPGIIPRKSVHEPMQTGLKSVDALIPIGRGQRELVIGDRQTGKTTVILDTFINQKPINQGTDESKKLYCIYVAVGQKRSTVAQIVRTLEEQGAMEYSIVVAATASDPAPMQFLAPYTGCAMGEFFRDNAMHAVIAYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDAHGAGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFFKGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYREMAAFAQFASDLDASTQKLLARGARLTELLKQPQFTPYPVELQVAVIFAGVKGYLDAIPTDKVVEFERRLVAELRGAQKDILDAIRNDREVKSETEAKLRSFLEGFVKNFTV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL23_AYWBP
Sequence: MNKYYDLVKAPIITELTNKLIERQNKYTFKVAKTANKVEIKKALESIFQVKVLSVNTRNVLPQFKRKGKFEGYTSGYKKAICKLAPGQKIKILANE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RIMP_CELJU
Sequence: MASKQERLTDLIVPVVESLGCELWGLEYLTQGRYTTLRIFIDGPQGVSLDDCERVSRQISAVLDVEDPIDGEYTLEVSSPGLDRPLYTEAQYARYVGETVNLRLRIAVEGRRRFKGVISAIEEGALLLQFDNQTVRLPIETIDKGNLVPRYDDILREHAAGLDE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SYMTH
Sequence: MIERRKTRAVKVGRVQIGGGAPITVQSMTKCDTRDVPEVLRQIRALEEAGCDIVRVAAPTMEAAECFKEIRKGCNIPLVADVHFDYRIALKVLEAGIDKLRINPGNIGARWKVEEVVRACKDRGVPIRIGVNAGSLEEEFLEKYGYPTADGMVESALKHVAILEELDFHDIVISIKSSRVDQMIEAYRKLSEKVDYPLHVGVTEAGTPFAGTIKSAVGIGTILAEGIGDTIRVSLSTDCVEEVRVGYEILKALGLRTRGINIISCPSCGRVQIDLVKVANEVERRLQHIDVPLNVAVMGCVVNGPGEAAEADVALFGGKGVGMLYVGGERVRKTTEEEMVEALVELVEQKAAEIKASGRVPTGYGRHEER
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: EFP_STRPB
Sequence: MIEASKLKAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDDTAYFMNTDTYDQYEIPVANVEQELLYILENSDVKIQFYGSEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATLETGLVVNVPDFIEAGQKLIINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOA_HUMAN
Sequence: MSILKIHAREIFDSRGNPTVEVDLFTSKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVSKAVEHINKTIAPALVSKKLNVTEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNSEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAANFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEGLELLKTAIGKAGYTDKVVIGMDVAASEFFRSGKYDLDFKSPDDPSRYISPDQLADLYKSFIKDYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAVNEKSCNCLLLKVNQIGSVTESLQACKLAQANGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKAKFAGRNFRNPLAK
What is the function of this protein?
MBP1 binds to the myc promoter and acts as a transcriptional repressor.  May be a tumor suppressor.
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, C-myc promoter-binding protein, Enolase 1, MBP-1, MPB-1, Non-neural enolase, NNE, Phosphopyruvate hydratase, Plasminogen-binding protein.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cytoplasm, myofibril, sarcomere, M line. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. ENO1 is localized to the M line. SUBCELLULAR LOCATION: [Isoform MBP-1]: Nucleus.
Protein: NUDI_SALPK
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: O2A25_HUMAN
Sequence: MGGNQTSITEFLLLGFPIGPRIQMLLFGLFSLFYIFILLGNGTILGLISLDSRLHTPMYFFLSHLAVVDIACACSTVPQMLVNLLHPAKPISFAGCMTQMFLFLSFAHTECLLLVVMSYDRYVAICHPLRYSTIMTWKVCITLALTSWILGVLLALVHLVLLLPLSFCGPQKLNHFFCEIMAVLKLACADTHINEVMVLAGAVSVLVGAFFSTVISYVHILCAILKIQSGEGCQKAFSICSSHLCVVGLFYGTAIIMYVEPQYESPKEQKKYLLLFHSLFNPMLNPLIYSLRNKEVQGTLKRMLEKKRTS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2A25, Olfactory receptor 2A27.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL40_PYRNV
Sequence: MPITLDPEKLAIVMKHRFQYKICRECGARNPPDAVKCRRCRSKNLRPKKFKKK
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: SCN2A_RAT
Sequence: MARSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDENGPKPNSDLEAGKSLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAISRFSATSALYILTPFNPIRKLAIKILVHSLFNVLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRNPWNWLDFTVITFAYVTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSTFEINITSFFNNSLDWNGTAFNRTVNMFNWDEYIEDKSHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAASAESRDFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQAGEEEKEDAVRKSASEDSIRKKGFQFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFNFKGRVKDIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRPSNVSQASRASRGIPTLPMNGKMHSAVDCNGVVSLVGGPSALTSPVGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPSRQRAMSMASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMHHFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIALGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEAEPEESLEPEACFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQMYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINYTTGEMFDVSVVNNYSECQALIESNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMTNILYWINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPEKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYEPITTTLKRKQEEVSAIVIQRAYRRYLLKQKVKKVSSIYKKDKGKEDEGTPIKEDIITDKLNENSTPEKTDVTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK
What is the function of this protein?
Mediates the voltage-dependent sodium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.  Implicated in the regulation of hippocampal replay occurring within sharp wave ripples (SPW-R) important for memory (By similarity).
What are the official names of this protein?
Sodium channel protein type 2 subunit alpha, Sodium channel protein brain II subunit alpha, Sodium channel protein type II subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.2.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.2/SCN2A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROC_FLAJ1
Sequence: MAGNSYGTLYKVTTFGESHGEALGGIIDGCPSGIELDFEAIEVEMSRRKPGQSAIVTQRKEPDAVQFLSGIFEGKTTGTPIGFIIPNTNQKSDDYSHIKDNYRPSHADYVYDQKYGFRDYRGGGRSSARETASRVVAGAIAKQMLPEIKINAYVSSVGPIHLDTPYQDLDFSKIESNPVRCPDEKSAAIMEEYIRDIRKQGDTVGGVVSCVIQNVPVGLGEPVFDKLHAELGKAMLSINAVKGFEYGSGFSGSEMKGSEHNDLYNPDGTTKTNLSGGIQGGISNGMDIYFRVAFKPVATIMQTQDSLDNKGNITPMTGKGRHDPCVVPRAVPIVEAMAAIVLADFYLINKTY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: KDSA_RICRS
Sequence: MQKVVKLNNIKIGNDLPFVLITGPCQIEGKDHALFMAEKLVKLTSKLEIPFIYKSSFDKANRTSVHGIRGVGIEKGLEILSKVKSEFDCPIVTDVHSESQCTATAEVADILQIPAFLCRQTDLLQAAAKTGKIVKVKKGQFLAPWDMKNVQTKLETFGVKDILFTERGACFGYNNLVSDMRSLAIMAELNVPVVFDATHSVQQPGGLGGSTGGERKYVELLAKAATSVGIAGMYMEVHQDPDNAPSDGPCMMKLDNLESILIKLKKYDKITKEK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_SHIF8
Sequence: MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_OCEIH
Sequence: MRTTFMANEANIERKWLVVDAEGQRLGRLASEVASILRGKHKATYTPHADTGDNVIIINADKIELTGNKINDKMYYRHSNHPGGLKERNAYEMRTKYPEQMLEIAVKGMLPKGPLGRKMGKKLHVYRGAEHNHQAQKPEVYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GSA_METTP
Sequence: MIRSHVSADTMNLNSSRSLYERAKRLMPGGVSSPVRAIRPYPFYVKRAEGPYLWDEDGNSFIDYCLAYGPMILGHRNPEVMRKVEEQIERGWLYGTPTALEVELAERIISHYPSIEMIRFVSTGTEATMAALRIARGFTGKDKIVKIEGGFHGAHDSVLVKAGSGATTIGVPDSKGVPADTAKNTVLVPYNDIQAMEAALREDDVAAVIMEPVLGNIGPVLPMDGYLEGVRRITEEHDALLIFDEVITGFRLALGGAQSYYRVRADITTLGKIIGGGFPIGAVGGRREIMENVAPQGGIYQAGTFNGSPVSMAAGLATLDILERGVLDRINEMGSYLRKGISDIVEDLKLDYSVSGVASMFKVFFGPLPRNYSEALRCDKEGYLRFFWRMLEAGIFLTPSQYETDFISASHDKEIIDKTLEAFKLFLKG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP88_DICDI
Sequence: MSFVVGFDFGTKNCTIAVAQKGGVDVIANEVSNRLTPSMVSFGEKERYLGESALTNQLRNIRNTITNIKRFIGQEFKTDTVQEELKHEMFQSYEMDNGFVGYNVTYAGEQCSFSSEAILGMLFGKLKKTTEAFVNNPVRDVVISVPVFWNDYQRRAILNAGSIAGLNIIRLINETTATALSYGIYKEWSETDPTNVLFVDVGDSATSVSAVQYKKGQLKVLGTASNPNIGSRVFDETLVKHFAKEFQTKYKINVFENKKALIRLRQACEKVKKILSSNNEAPVSIDSLMDDKDVKGMIDRATFEELANDDMNTIVEPLQRLLSELQMTPDQFQSIEITGGGTRSTSLQKKLSEVLGRDLSKTINSEESVCRGAALQCAMLSPVFRVRPFAVNDVASYPVSVHFKSVSGVEQKLDLFNLKSAIPTPKPLRISFPVTKAEGFEIVVNSTFGTIATVKVDNIPAFTNKSSIKAKVWLDIHGIFHIDEVKLVEQIPEEETAAPAETPAETPANGEAAKPAEEKKVKVKETSLVFTTSRKGLTNELLKAAIEEEGRMQASDLLAIETAEKKNALESYIYDMRSKLQSSLKEYVTPADAETFMTQLNKQMDWLESEEGEDQTKSVYAGKLEELRRLGNPIQKRKQDLEDYPDAVQTLKNIASYVKNEAMIPGERYDHIEKEEKEKLCKDCDDAVEWIDALVAKQQATPKTQPCIINTTEVLAKKTQLEVTAKMILGKPKPKPVEVPKEEPKDTPMESKDAPAEEPVATKDQKMDDILD
What is the function of this protein?
May function in protein folding and assembly, and disassembly of protein complexes.
What are the official names of this protein?
Heat shock protein 88, Heat shock 70-related protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.