PharMolix/UniProtQA huggingface dataset:
Protein: C3H34_ARATH
Sequence: MERYGRPGEEGSRSDPSLEWTSHGGETAVEAPMWRLGLSGGGGGGGGGESYPERPDEPDCIYYLRTGVCGYGSRCRFNHPRDRGAVIGGVRGEAGALPERMGHPVCQHFMRTGTCKFGASCKYHHPRQGGGGGSVAPVSLSYLGYPLRPGEKECSYYLRTGQCKFGLTCRFNHPVPLAVQGPPQQPQQQQPQPQPQLQTIYPTLQSQSIPSSQQYGLVLTRPSFLTGSYLQSPYGPPMVLPPGMVPYSGWNPYQASLSAMPSPGTQPSIGSSSIYGLTPLSPSATAYTGTYQSVPSSNSTSKEFPQRPDQPECQYFMRTGDCKFGSSCRYHHPVDAVPPKTGIVLSSIGLPLRPGVAQCTHFAQHGICKFGPACKFDHSMSSSLSYSPSASSLTDMPVAPYPIGSSSLSGSSAPVSSSNEPTKEAVTPAVSSMVSGLSRPEPAETSGDSASVSGSIEAKTSS
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 34, AtC3H34, Zinc finger CCCH domain-containing protein ZFN-like 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAZ_ECO8A
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DYNA_NEUCR
Sequence: MSELGVAVGQKIELADGSGRTAFVRYVGETAFAPGTWVGIELDEPSGKNDGSVQGERYFNCEMGYGMFVRPTTFNVIAQPPPPPPPSTFRRSVTTRPTSLNASTTRRPAPVDSGLAKRMSLNAPSPSPGPRPSRTSSTSITRSPTRSPTKQLATASSSGNPSRSGTPSTTTKPAGPTTRTRPSLSTSRHSMGPPPTPTTRTTRKPSVSSVGTRPSIGATRPVGGRASMSARSSTNRLSDPRESTGSVSSVGKSGFKRGSASPRSSDEELSASPVPASPVHQKTAALEKLTAPGAGNGGGGASPGATSPNLKATTITPRSSITNTATMNKEIEDLKAKLKVLEKKRMEDREKLNSLEKVKAERDKFERIIQTLQIKYQPQQQEIQDLKRQLKEAENRLYNVEELQAEHDTAMELATLDREMAEETAEVLKVELDALKQKNEELELEVEVLREENSEFTNGMSPEERASTGWLQMERNNERLREALIRLRDITQQQEEELKDQIKSMEEDLREFETIKEQHTTAKEKLAQTEAIVEDLREQLNNALGAEEIIESLTEQTMNQSEEIKELRAVIDDLESLKEINDELEINHVQNEKEMQEEIDLKDSIIAEQFRQANLQRESLEDMEYTLSRFRELVTSLQSDLEDMRASHAVTENESEQLNSRSRAMLDLNMKLQISASKAQVKTIDLELRRMEAQEAEQHLEIVKLFLPDTYQSDRDSVLALLRFKRLAFKANLLNGFIKERVNGQPHPGHEDDIFDGCDAIDKLTWVSAMCDRFVNAISHCSLEQFSRYEGALYELEPVERALNGWIDGLRRDDLKEKQCADELKRTIALMTHLGEVHISNDLESFADDVHMKALLMQSHLESAAISVNSLKAMVQRVIPSSGEDDELAQYFSKRAEAVVSQTRSAKVIAGKTVRALEDLKTRSLSLTPDTLEAFEQSETATRDLANMARQIGLDLHAFLHEEGRTEPYNYMEVQSCIQRSAQASSPTASSPESDLFNTYLSYLRNATSTISDLASLASDLAQTQEFDRTPAPWILRSAELKAAKTVAPDINDELRRLRDDIAEARRSIAVREEMLSTAQVKIETLESRMRDANAKAARIVDLEADLQAAKKEAAQLQEDMEKQDRELKALESDRDKWKKIASESRVVVADGSGVGVDNKASAERAVATAREMDALKKEIEALQAAVRYLREDSRRARLKEQGDYEWLAEPLVKKKPSVQEQRKQLVKKEGKAVLGELVKLVSSAKVFDLGSLPEKAEDRLKWRPAKTTPGWWVAKQMEDWEALKEWEGSVKGRVRELGGVPGSKKAEREEEAKRMVRRTAAAKLQIRLPGMEGKVGHGGGGGSGRRVQIVGSREWESLQGRLAVVV
What is the function of this protein?
Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules.  Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles (By similarity).
What are the official names of this protein?
Dynactin, 150 kDa isoform, 150 kDa dynein-associated polypeptide, DAP-150, DP-150, p150-glued.
What is the protein family that this protein belongs to?
Belongs to the dynactin 150 kDa subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: SPEE_ECOK1
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTNQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_SALNS
Sequence: MRSSAKQEELVRAFKALLKEEKFSSQGEIVLALQDQGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVRDLYEAILELFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMMR1_MOUSE
Sequence: MAAGCCGVKKQKLSSSPPSGSGGGGGASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLSGGGGSGGGGGCPLSPPQGCGGGGGGGGGGGSGSGGGGISLSPPLSCGVGTLLSTPAAATASSPSSSSSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVCDYLDWEVGVHGIRIEFINEKGSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFRKTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS
What are the official names of this protein?
Nuclear protein AMMECR1, AMME syndrome candidate gene 1 protein homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECA_PROM9
Sequence: MSLEEKKKPESKEKDKALSLVLGQIERNFGRGSIMRLGDASRMKVETISTGALTLDLALGGGYPKGRVVEVYGPESSGKTTLTLHAIAEVQKNGGVAAFVDAEHALDPVYAASLGVDVENLLVSQPDTGEMALEIVDQLIRSSAVDLVVVDSVAALTPRAEIEGEMGDHVIGSQARLMSQAMRKITGNIGKSGCTVIFLNQLRLKIGVTYGNPETTTGGNALKFYASVRLDIRRIQTLKRGTEEYGIRAKVKVAKNKVAPPFRIAEFDILFGKGISTTGCLLDLAEETNIIIRRGAWYSYEGENIGQGRDNTIIWLDQNLEIRNKVESMVKEKLTEGTEVSSNSMKALNSNPANTIAVNDIKTVA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_SHEB5
Sequence: MSKRDYYEVLGVSRDTSEREIKKAYKRLAMKFHPDRNPGDKTAEANFKEIKEAYEILTDADKKAAYDQFGHAGVDPNRGGGGYGGGQGDFGDIFGDVFGDIFGGGRRGGQRQAARGSDLRYNLELSLEEAVKGLTKELRIPTLATCDLCEGSGAKKGTSATTCGTCHGQGQVQMRQGFFAVQQPCPTCHGRGKIIKDPCTKCHGDGRVEKSKTLSVKIPAGVDTGDRIRLAGEGEAGEFGAPAGDLYVQVSVREHAIFVRDGNNLYCEVPISFSKAALGGEIEVPTLDGKVSLKIPAETQTGRMFRLRGKGVKSVRSHAVGDLLCKVVMETPVNLNDRQKELLREFEATLTGESKKHSPKAEGFFDGVKKFFQDLNS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HB2C_PIG
Sequence: MSGMVALRLPRGLWTAALTVMLVVLGAPVAEGRDSPQDFVFQFKGECYFYNGTQRVRGVARYIYNQEEHLRFDSDVGEFRAVTPLGRPEADSWNSQKDVLEQMRAEVDRVCKHNYQIEEGTTLQRRVQPTVTISPSKAEALNHHNLLVCAVTDFYPSQVKVQWFRNGQEETAGVVSTPLIRNGDWTYQVLVMLEMNLQRGDVYTCRVEHSSLQNPILVEWRAQSESAQSKMLSGVGGFVLGLIFLGLGLFIRHRSQKGLVR
What are the official names of this protein?
SLA class II histocompatibility antigen, DQ haplotype C beta chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ISPF_SALA4
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLMKAAK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TACAN_DANRE
Sequence: MLFNPTGLTECLQEWEDLEKDYQQIQDTHRHYKHKLEEVSKLQESCSSSIARQRKKLKDLSESLEECKGAVNPEDVNKIDDIQESIKERPNVFFEMEAFLPKKNGLYLSLVLGNVNVTLLNKQSKFAYKDEYEKFKLYLTVLLLFFSFTCRFLVSYRVVDALFNFLLVWYYCTLTIRESILINNGSKIKGWWVFQHYVSTFLSGVMLTWPDGELYQMFRNQFLSYSMYINFVQFFQYYYQSGCLYRLRALGERHNMDLTVEGFQSWMWRGLTFLLPFLFLGHFFQLYNGITLFQMTQLPEWKEWQVLMCGSTFLVLFMGNFFTTLGVVYHKYMDQDKAKGL
What is the function of this protein?
Ion channel involved in sensing mechanical pain.  Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli.  May also be required for efficient adipogenesis.
What are the official names of this protein?
Ion channel TACAN, Transmembrane protein 120A.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Protein: ARGB_SERP5
Sequence: MNPLIIKLGGVLLDSEEALERLFTALDSYRQQHQRPLVIVHGGGCLVDELMKKLSLPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAIKHQINAVGLSLADGGSVTVTPLDPALGHVGNAQPGSPLLLNTLLGAGYLPVISSIGITADGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARTLGRPVDIASWRHADQLPALFNGVSIGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP2AB_THEP3
Sequence: MEYTNMMELNFLSKSQNESFARTVVAAFAAQLDPTIEEIADIKTAVSEAVTNCIIHGYENKIGIITIKAFISGNKITIEVIDEGKGIEDIEKAMQPLFTTRLEEERAGMGFTVMQTFMDELEVESTPGKGTLVRMTKYIGSDK
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: SYF2_DROPS
Sequence: MEQSKSASDKLAERKARLLDLHKKRQEARTDNHQEVVAEDARKKLPKNWEARKRQAEWLLADDKAREDAQAAGKDYERLKLLEVSAIDAERIEKKKKRKDNPDLGFSTYEAQTARQYSRLVKGMPARDMEKYEKQKAELGEAFYGGPHTTLHALTKDTPAAINKMVNDLDQQIERRKKYSRRRIYNDDADVDFINERNSKFNKKLDRFYGEHTAEIKQNLERGTAI
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor Syf2.
What is the protein family that this protein belongs to?
Belongs to the SYF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAL5_YEAST
Sequence: MSADASTNSNASLDEKNLNITSEAEIKNEDVTAEPVLSTVLSPNGKIVYISDKVDEAMKLAEEAKEIEVTPEEDRKLRWKIDYCMFPLMCILYAVQFMDKISTSSAAVMGLRTDLKMHGDQYSWVTSAFYFGYLFMNLGPVQFIFQRTSHMSKMLAVFIVIWGMLLALHAAPTVKYPSFIVLRVLLGCAESVVTPCFTIITAQYWKTEEQFTRVSIWFGMNGLGSILINAIAYGVYIHQDSYAIKGWRTLFVITGVITIFIGILIFLWIPDDPSKARFLSKREKLMVVQRIRSNQQGFGNHEIKKYQIIEALKDVRTWLYFLFTVSSNIPNGGISSFMSILLNSDFGYSSKETLLMGLPTGAVELVGCPLFGILAVYAANKKIPFWKYKLSWAIFAAVLALIASCMLGFATNSKKARLAGAYLWYISPVSFICVLSNISANSSGYSKKWTVSSINLVAYAAANLAGPQTFIAKQAPKYHGAKVAMVVCYAVMIVLLSILLIVNLRENKRRDKIAAERGFPEETENLEFSDLTDFENPNFRYTL
What is the function of this protein?
Component of the allantoate transport system.
What are the official names of this protein?
Allantoate permease.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Allantoate permease family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS4_CALMQ
Sequence: MGDPKRPKKKYVEGKPKRLWNSDLLMSELRLIGEYGLRNKKELWLARALLRSIKHRAREILSAPMEIRGEAEKRLKDRLFRMGLISDINIPLDSVLALDVTAVLERRLQTLVYRKGMARSIHEARQLIVHGHISINGVRVRSPGYLVPRNLEDGIGFAPTSRIVKAKVTQQVNQGGQAVNQ
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: REEP5_PONAB
Sequence: MSAAMRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQVDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST
What is the function of this protein?
Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
What are the official names of this protein?
Receptor expression-enhancing protein 5, Polyposis locus protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the DP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes to endoplasmic reticulum tubular network. In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery.
Protein: RL9_CLOBH
Sequence: MKVILLKDVKSLGKKGDLVNASDGYARNYLIPKKLAEQATENNVHILNNKKEAERRQKLKELEEAQKLAKSLMGKEIKFKVKIGENGRLFGSITSKDISEKLKEQYNMNIDKKKIVAETIRQTGVYEAEIKIYPEVSTKVKVSVLEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: INT4_MOUSE
Sequence: MAAHLKKRVYEEFTKVVQQQQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGSKLPENQATQVRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDTEGSAARDVQKIIGDHFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTLRHYAYLRDSLSHLVPALRLPGRKLVSSTVPSNITPHEDPSQQFLQQSLERVYSVQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLQCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIQHMRLQAKALQLIVTARTTRGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDKLLDLMPRLMASKPVEVIKILQTMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLLTQVYLSHTAWTEPCQVEVRLLLAYNSGARIPKSPWLEGSEMSPQVETSIEGTIPFSKPVKVYIMPKPARR
What is the function of this protein?
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 4, Int4.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CARME_MOUSE
Sequence: MQRRQRAPPASQPAQDGGRSEDVEVQFSAGRLGSAAPAGPPARGTAEDEERLEREHFWKVINAFRYYGTSMHERVNRTERQFRSLPENQQKLLPQFPLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDANGKIMPASTFDMDKLKSTLKQFVRDWSETGKAERDACYKPIIKEIIKNFPKERWDPSKVNILVPGAGLGRLAWEVAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPILFPDVDPHSLPPGSNFSMTAGDFQEIYSECNAWDCIATCFFIDTAHNVIDYIDTIWRILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFQLEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ
What is the function of this protein?
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine.  Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles.  Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
What are the official names of this protein?
Carnosine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the carnosine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: DEOC_YERPG
Sequence: MTTNYAHYIDHTLLAMDATEAQIIKLCEEAKQHHFYAVCVNSGYVPVVAQQLAGSSVKVCSVIGFPLGAGLTAAKAFEAQAAINAGAQEIDMVINVGWLKSGKIADVKADIKAVRDNCAATPLKVILETCLLSDEQIVQVCEMCRELDVAFVKTSTGFSTGGAKEEHVKLMRATVGPVMGVKASGAVRDRATAETMIQAGATRIGTSSGVAIVSGQQAAASGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY197_POSPM
Sequence: MVFVTTTNVLLSMSGAIAAIVLWKVISILRAPYTSALRNLPGPPSPSWPLGHLKMMFSAEDSAALYESWVERHGTTFKYNGWAGTYRLFTADTRAVNYIQSHSNDYWKPEISRFSLIQILGHGLLSVEGDRHRQQRRVMNPAFGPAQIRGLTEIFVEKAHKLCEFWRNELSKNGEPGRIEVLNGLSKMTLDVIGLAGFNYDFNSLNVDGKPNELNEAFNVLFRSLDGFAILPVLQAVFPPLRLLPDRRSRRIASAVKVMRRIGMELISNKKAEIVAAAISDQKEKNKLQSRDLLTLLLKSNLSRDNPESQRLSDKDVLAQVPTFLIAGHETTSNAVAWCLYALTQNSEIQQKLRDELWSVPTEDPTMDELNELPYLEAVVRETMRVHAPVPATERVAIKDDVILLNTPYIDIRGQVQDSVRVRKGDHIFIPIIAMNKSKALWGEDAFEFKPERWESIPDAVQTIPGVWANMMSFLGGAHSCIGFRFSVVEMKALVFALVRSFEFELAVPAGQLTAKTIGVQRPAVRGEQNQGCQLPLLIKVYKRN
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use carbazole as a substrate for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 197.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GYRB_TREDE
Sequence: MTKSNYSANNITVLKGLEAVRKRPGMYIGSTGPDGLHHLVYEVVDNCIDEAMAGFCDKILVVLEPNDIVRVEDNGRGIPVDIHPTEKISALELVLTRLHAGGKFDKGSYKVSGGLHGVGVSVVNALSVWMEAKVYKDGFEHYAKFEKGSILEPVKKIGETEKSGTVIRWAVDPSIFTETTVYNFEVLATRLRELAFLNSKISITMRDERLSTPKEVTFAFEGGISQFVSYLNESKQVFPKSPVFIEGEKNDILCEVAIQYNDGYNENLLSFVNDINTREGGTHLEGFKTALTRVMNDFLKKYPKLVKKMDKEEKLTGEDVRAGLTAIVSVKVPEPQFEGQTKTKLGNSDVRGIVDSFVNEKLTLFFEQNPNEVEKVLEKCVAEAAARIAARRAKEATRRKSGLDSFGLPGKLADCSLKDPESCEVYIVEGDSAGGSAKKGRDSKTQAILPLWGKMLNVEKTRLDKVVNNEKLQPIIATLGTGIGKDFNIEKLRYHKVIIMADADVDGSHIRTLLLTFFFRYMPQVIEKGHVYLAMPPLYKISHNKKEWYVYNDDERDSVLDQIGRGNNAAVQRYKGLGEMDGTQLWETTMDPARRKMMRVTLPDAVEADRIFSTLMGEEVEPRRKFIEENAVYANLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_BARHE
Sequence: MLTCKQYELLLFIHNHMKETGVPPSFDEMKTALELTSKSGIHRLITALEERGFIRRLPNRARAVEVIRLPEKITFNLSSARKISPSVIENNKRKISKNSDNFDLEEKKNIIIPIMGRIAAAVPISAIQQQINTLCLPQDMISLGEHYALEVKDDSMIEAGILDKDIIIVRRQNTATSGEIIIALIDKEEVTFKRYRRKGNSITLEAANPHYETRIYRPERVQIQGKLIGLIRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: HRCA_DESRM
Sequence: MKMDERKQQILLAIIKDYINTAEPVGSRTISRKYKLGVSPATIRNEMSDLEEMGYIEQPHTSAGRIPSNLGYRYYVDCLMQREQLSEEEEVTIRRGYENKVREVGEVLNRTGRMMAQLTHYTALVQMPSFRRSAYKHVQMVLMGPSQAILIVVMDTGAVHHQMMTVPESITQQDLDQISSVLNAKLQGRTMDNIRLTLIKEIYFELSKHRSILDLALELMQDRVISVAEDKIYLEGVFNILNQPEFHNVERVKILLSLLEQEDTLKDILDFTRDRQGITIKIGNENLRQEIQDCSMVTATYQVGDKILGTIGVLGPTRMDYARVVTVIDCMSRNLSRTLDRILKGQV
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RL8_MOUSE
Sequence: MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECB_RICCN
Sequence: MSTINTDTNETMPHISVNAQYIKDLSLENPSAPSSLAALDQRPQIDLSLDINITNLSEENFYEVELNIEAIARNEKYKLFQIELKYAGVFNLINIDSEQHPVLLSVHCPAMIFPFARKIIASCTQDAGFQPLMIDPIDFGALYHKKMSEHQN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.