PharMolix/UniProtQA huggingface dataset:
Protein: PYRB_CLOK5
Sequence: MLKGRHLIDAMDFSIEELEEIFKLSNEIISREKEFSHICEGKLLATLFYEPSTRTRLSFESAMLRLGGKVMGFSEPGSSSASKGESIADTIRVISCYADIAAMRHPKEGAPKIAAMYSNIPVINAGDGGHQHPTQTLTDLLTVKSIKGRLSNLKIGCCGDLKFGRTVHSLIKAMSRYENNSFTLISPEELKIPNYLKKELNSKNVKYEETKNLEDSIESLDILYMTRVQRERFFNEEDYIRLKDSYILDKGKISRAAKDMIVLHPLPRVNEISYEIDKDPRAYYFKQAKYGMYVRMALMIKLLGIQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ARNA_AERHH
Sequence: MKVVVFAYHDIGCTGIEALLEAGYEIQAVFTHADDPGENRFFGSVAQLCAEHNLPVYSPEDVNHPLWIERIRELAPQALFSFYYRNMLKQAILDIPTVGAFNLHGSLLPAYRGRAPINWCLVNGEAETGITLHQMTAKPDAGAIVAQQAVTIADDDTALTLHGKVRLAARALLEQELPKLRAGDIRLTPQDESKASYYGRRTPADGELHWHRPARELHNLVRAVTQPYPGAFSFAGDRKLTVWKSHWLAQQSDKQPGTILSQEPLRIACGEGVLEIVAGQAEGGLYVRGAQLARELGLVEGMKIGAKASNALRKARLTRVLILGVNGFIGNHLTERLLQDGGYEVYGLDIGSSAVDRFIGHPNFHFVEGDISIHTEWIEYHIKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLKIVRYCVKYHKRIIFPSTSEVYGMCDDHSFDEDSSRLIVGPINKQRWIYSVSKQLLDRVIWAYGKKEGLNFTLFRPFNWMGPRLDSLDSARIGSSRAITQLILNLVDGTPIQLVDGGAQKRCFTDIEDGIEALFRIIENKENRCDGQIINIGNPDNEASIQQMAEILLAKFEAHPLRDHFPPFAGFKLVESKSFYGDGYQDVSHRRPSIANARRLLDWEPTIEMEETIGNTLDFFLQGAVTTGVEHD
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: MSBA_XANCP
Sequence: MKTINENAPQVSSWQTYRRLLAFAKPYRLLLVAALIAALIEAAGTTGFLALMKPITDETFIYKNAEVSRWLPVQIILLFVIRGAAGYITDMAMGKSARSIARDLRVKVMSKYLRLPGSRFDSEPVPSMLIRLGSDSDQVAQAAVDAVKVMIQQSLQVIGALALMLWHSWQVTLTILVLAPVLAWVMDKVARRYRRISHSIQESGAHLLQAADQTLSSHQEVKIYGAQQSEMERYSGLADRNLRLAMKVESTRGISTATVQMIGAIGLSALLFVAGAQALAGRLTAGDFVVLMTSMLTIIPGLKQLTNVQNMVQRGLASAERLFSVLDSPDEPDQGQVPLTRAKGLIEFRDVTARYPGQANPALADVSFVAQPGTVTAIVGRSGSGKSSLIKLIPRFYEAESGQILLDGHPVQAYALADLRRQIALVGQQVMLFDGSIAENVAYGEMRQCDAGQLERAIQGANAMEFVAQLPEGLQSHVGTKGGRLSGGQRQRLAIARAMLKDAPILILDEATAALDNESERLVQDALHKLMPDRTTLVIAHRLSTIEHADQVLVMDQGRIVERGTHQELLALGGLYSHLHGMQFRERQA
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISCS_SHEFN
Sequence: MKLPIYLDYAATTPVDPRVAEKMMQHMTMDGVFGNPASRSHRYGWQAEEAVDVARNQVADLINADHREIVFTSGATESSNLAIKGIAHFYHKKGKHIITSKTEHKATLDTCRQLEREGYEVTYLVPDANGIIPMERLEAAMRDDTILVSIMHVNNEIGVIHDINAIGELCRSKGIFFHMDAAQSAGKIPIDVQTTKVDLISISGHKMYGPKGIGALYVRRKPRIRLESQMHGGGHERGMRSGTLATHQIVGLGEAAAVAKQDMAADSARITHLRDKLWNGIKHIEETYINGDMEQRYSGIFNVSFNFVEGESLMMALKDLAVSSGSACTSASLEPSYVLRALGLNDEMAHSSIRFSIGRFTTDEEIDHAIKTITESIDKLREMSPLWEMFKDGIDLEQVQWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_ALCBS
Sequence: MAKSKKDSGARRKKVTRTVADGIAHVHASFNNTIITITDRQGNALSWATSGGAGFRGSRKSTPFAAQVAAENAGNAAKDYGLKNLEVRVKGPGPGRESSIRALNGCGYKITHIEDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CHLL_PROM1
Sequence: MTSTITRKEDGEGSVQVKQDPKAQIQEGALVIAVYGKGGIGKSTTSSNLSAAFSKLGKKVLQIGCDPKHDSTFTLTHKMVPTVIDILEEVDFHSEELRPEDFMFKGFNGVMCVESGGPPAGTGCGGYVTGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFAAPLQHANYCLIVTANDFDSIFAMNRIVAAINAKAKNYKVRLGGVIANRSAELDQIEKFNERTGLKTMAHFRNVDAIRRSRLKKCTIFEMDSEEEGVVEVQNEYLSLAQKMIDNVEPLEAEPLKDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: NTRC_RHILP
Sequence: MTATILVADDDAAIRTVLNQALSRAG
What is the function of this protein?
Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation.  Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
What are the official names of this protein?
DNA-binding transcriptional regulator NtrC, Nitrogen regulation protein NR(I), Nitrogen regulator I, NRI.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTU_THEAB
Sequence: MERIIRAPRGTTLSCKSWQTEAPMRMLMNNLDPEVARDPANLIVYGGTGRAARNWQCFDKIVETLKTLEMDETLLVQSGKPVAVFKTSEWAPRVLIANSNLVPKWANWEYFRELEERGLIMYGQMTAGSWIYIGTQGILQGTYETFYAVAKKYFGGTLKGKWVLTAGLGEMGGAQPLAVTLNDGVVLAVEIDKRMIERRLNTGYLDTWTDNLDEALEMVQKAVKEERPLSVALLANAADVHPELVKRGIIPDIVTDQTAAHDPLTGYVPAGMSFEEALKLRKENPQKYLELVYESVVKHINAILEMQKQGAKVFEYGNNIRRLAYDHGVKDAFNIPGYVPEYIRDLFAEGKGPFRWAALSGNPEDIYKTDKKVLELFPYDDHLRKWIELAQKKVKWQGLPARICWLGQGERAEFGLAINEMVKKGELEAPIVIGRDHHDTGSVASPYRETEAMKDGSDAIADWPILNAMLNVASGATWVSFHHGGGVGIGYSLHAGMVIVADGTDLAHKKLERVLTNDVGLGVVRHADAGYEIAIETAKKHNLRMPMLD
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAM7A_DICDI
Sequence: MSQTDILYACVSYKGVCLVEHKIANGNFIDLARRLITKIPPTSKKIYTSENHNFHYISENDLAFLCLCHEKLGVQIPSEFLSDIRQQFIRSYGQSFSQNSPTATYDPFIRVLEERMKYYSNPKSNKMNLVMDQVSEAKGALTDAIEKTIHRGEKIEIIVDKTERLQSESFVFKSNSVALKRKLWWQNKKLAIAIGLVVCILIAVITLALLKYFKVI
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome.  Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion.  Required for calcium regulated lysosomal exocytosis.
What are the official names of this protein?
Vesicle-associated membrane protein 7A.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type IV membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Late endosome membrane; Single-pass type IV membrane protein. Lysosome membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type IV membrane protein. Note=During macropinocytosis highest levels are found in endosomes with lower levels observed in the lysosomes.
Protein: PDXT_BIFAA
Sequence: MTGILAVQGAFAEHAAMLDHLGAPWKLLRAAEDFDDSIDRVILPGGESTTQGKLLRSTGLFEPIAEHIAAGKPVFGTCAGMILLARKLDNDDNVYFGALDAVVRRNAYGRQLGSFAATADFGSSSGDSAVVVAPGEHVPQDAPADIVLKDFPLVFIRGPFVAEVGPAATVETSVDGNVVGLRQGKILATAFHPELTDDTRIHELFLSL
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: SSRP_CAMC5
Sequence: MKDLAKNKKALHDFSILETFEAGVVLKGSEVKALRAGRANLKDSFVRIIKGEIFLLNAHISHLDTTNSHFRPDERAPRKLLMHRKQIDKLFGSVTKDGLTMVALALYLNDKNIIKARVALAKGKNLHDKRETLKKREADMEARAAMKKFI
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CYB_MICLO
Sequence: MTIIRKKHPLIKMINHSFIDLPTPSNISSWWNFGSLLGLCLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIHYVGTTLVEWIWGGFSVDTATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYFTVKDFLGVLILLMVFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILALMPLLHTSKQRALIFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQAASIAYFAIIVILMPIAGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BIOB_SORC5
Sequence: MLEGIEREAAEHSNGCSGPAGHAPPAGAPRHDWTVQQAVALHDLPLFELIDRARAVHRAFHGEHEVQLCTLLSVKTGGCPEDCAYCPQSSHYETEVGPERMLDVGAVLAAAERAREGGSTRFCMGAAWREVKDGPAFERVLDMVRGVKALGLEACCTLGMLTDDQARRLKEAGLDAYNHNLDTSRKAYKSIISTRTYDERLVTLRNVRRAGITVCSGGIIGMGESIADRCEMLVELARLDPHPESVPINALVRSPGTPLESLPPVDPIEFVRMIAVARVMMPRAMVRLSAGRTELSRETQLLCMYAGANSIFYGDRLLTTPNPGQDEDRALIEKAGLQPMAPAAARAAR
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NDHK_ANTAG
Sequence: MVLVPKYLNFESDLAESVTNSMDSSLPDETTSDSIILTTFNDFSNWARLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLIITAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDIYLPGCPPKPEAIIDAIIKLRKGVAREVHERKDKLRQTRRYFTLNHQLEIVPIIHTGKYDEHLFSKFSEISIEPKLNVSPQRIEKSKSSISSQISF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: WBP11_MOUSE
Sequence: MGRRSTSSTKSGKFMNPTDQARKEARKRELKKNKKQRMMVRAAVLKMKDPKQIIRDMEKLDEMEFNPVQQPQLNEKVLKDKRKKLRETFERILRLYEKENPDIYKELRKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPDMPHAPSNILIQDIPLPGAQPPSILKKTSAYGPPARAVSILPLLGHGVPRLPPGRKPPGPPPGPPPPQVLQMYGRKVGFALDLPPRRRDEDMLYSPELAQRGHDDDMSSTSEDDGYPEDMDQDKHDDSTEDSDTDRSDAESDGDEFGHREDSERDNTEEKKSGLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEEEDADDSDDSEAEKQSQKQHKDDGHSDSTAAASSQQQAPPQSAPASQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGIRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPSLIQRPKADDASAATIEKKATATISAKPQITNPKAEVTRFVPTALRVRRENKGATAVPQRRSEDDSAVPVAKAAPRSGPSVAVSVQTKDDVYEAFMKEMEGLL
What is the function of this protein?
Activates pre-mRNA splicing.  May inhibit PP1 phosphatase activity.
What are the official names of this protein?
WW domain-binding protein 11, WBP-11, Splicing factor that interacts with PQBP-1 and PP1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly located in the nucleus with granular heterogeneous distribution. Excluded from nucleoli in interphase cells, distributed throughout cytoplasm in dividing cells. Colocalized with SC35 and U2B in the nucleus. In the cytoplasm, associates with the intermediate filament protein vimentin.
Protein: MIAA_AYWBP
Sequence: MKKVIAITGPTASGKTSLSIKIAKKFNLEIINCDSLQMYQKYDIGTAKITIEEAQGIKHHLLDFLTPGTNYNIYYFQKDARKKIEEMPLPLFVGGSGLYLKSVLFDYELTPKSLFLPPISLTAIENMVDFIKKKDPQLIANLDLKNPRRILSAYQDLLSGTLRSQKNKKHNPLYSSLIFYLDIDRQILKKRVILRLEQMLKKGFIEEVNQIQTFFPNANFNIIGYREIKVLLEGKITLDQAKTLIIQKTMQYAKRQKTWFKNQIKPMILDALSPDLEKTTIGLINNFLKTD
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HTPG_BURO1
Sequence: MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDPNLRIRIGYDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGDFTIDAIERAQRGTTITLHLREGEDDLLSSHRLKSIIQKYSDHIALPILMRKEEWDQEKGEMVLKDEDETVNQASALWTRSKSDVTDEQYTQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWGAFGQVLKEGLGEDHANRERIAKLLRFASTHGDTDAQDVSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHEFDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLTDSPSCLVADDNDMSGYLQRMLKAAGQNAPAMQPILEINPEHALVKQLNADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
Protein: TBB2_EMENI
Sequence: MREIVHLQTGQCGNQVGSAFWQTISGEHGLDASGIYTGDSDLQLERMNVYFNEAGGNKYVPRAVLIDLEPGTMDALRSGPNGALYRPDNFIYGQSSAGNNWAKGHYTEGAELVDQVIDVVRREAESCDCLQGFQVTHSLGGGTGSGMGTLLISKIREEFPDRMMATFSVMPSPKVSDTVVEPYNATLSVHQLVEHSDETFCLDNDALYDICIRTLKLSSPSYGDLNHLVSAVMSGITVSLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRSSSSFRTISVPELTQQMFDSRNMMTAANYQNGRFLTCSTLFRGKVAMKEVEDQMRNMQNKYSSYFVEWIPNNVQTALCSMPPKGLKMAATFVGNSTSVQELFNRVSNQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLMSEYQQYQEATVSDGEGAYDAEEGEAYEQEE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2 chain, Beta-2-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ADDA_STRP4
Sequence: MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNILVSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQETDDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLENEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWLSESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQFTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILENFPQVRESYQERFHEVMVDEYQDINHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVGEINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEILKLHQEKGVAFKEIALLTSSRNRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKAHENLYEKLVNAQKKASSQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIHKSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQDSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTALGQEIFANTDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLILLGKDEVQVVKV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: ESXR_MYCLE
Sequence: MTQIMYNYPAMLDHAGNMSACAGALQGVGIDIAAEQAALQACWGGDTGISYQAWQVQWNQATEEMVRAYHAMANTHQNNTLAMLTRDQAEAAKWGG
What are the official names of this protein?
ESAT-6-like protein EsxR.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-3 / type VII secretion system (T7SS).
Protein: RL29_MYCPA
Sequence: MAVGISPGELRELTDDELTERLRESKEELFNLRFQMATGQLTNNRRLRTVRQEIARVYTVLRERELGLASGPDGKES
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RIPP2_HUMAN
Sequence: MENAGGAEGTESGAAACAATDGPTRRAGADSGYAGFWRPWVDAGGKKEEETPNHAAEAMPDGPGMTAASGKLYQFRHPVRLFWPKSKCYDYLYQEAEALLKNFPIQATISFYEDSDSEDEIEDLTCEN
What is the function of this protein?
Plays a role in somitogenesis.  Required for somite segregation and establishment of rostrocaudal polarity in somites (By similarity).
What are the official names of this protein?
Protein ripply2.
What is the protein family that this protein belongs to?
Belongs to the ripply family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL2_MYXXD
Sequence: MGIKKYKPTSAARRLMTVSDFADITKDSPEKSLTEPLKRSGGRNVHGHITRRHQGGGHKRRYRVIDFKRRDKDGVPAKVVAVEYDPNRTANIALLHYADGEKRYILAPVGLSVGDTVFAGEGADIRPGNSLPLQNIPVGTVIHNVELKPGRGAQVIRSAGTSGQLMAKEDRYAQVRMPSGTVRKVLIECRATVGQVGNIEHEIIRIGKAGKSRWLGIRPTVRGLAMNPVDHPHGGGEGKSGQGNPHPVSPWGKKTKGLTTRTNKRTDKFIVSGRRQGARSQ
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: LUXS_SHEWM
Sequence: MPLLDSFTVDHTRMNAPAVRVAKTMKSPSGDTITVFDLRFCAPNKDILSERGIHTLEHLYAGFMRNHLNGDNVEIIDISPMGCRTGFYMSLIGSPKEADVAEAWLASMNDVLTVASQSEIPELNEYQCGTFNMHSLEQAQGIARSIIASGISVNKNDELKLSEKILKGL
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: SYK_PROMH
Sequence: MSQQQQGAEQAPDLNNELQTRREKLSALRDNGNAFPNDFRRDAMSDELHQKYDAMSAEELDAANVEVAIAGRMMTRRIMGKASFATLQDMGGRIQLYVSRDDLPEGVYNEQFKKWDLGDILGGRGRVFKTKTGELSIHCTELRLLTKALRPLPDKFHGLADQETRYRQRYLDLISNENSRNTFKIRSKIMSAIRQFMVNKGFMEVETPMMQTIPGGASARPFITHHNALDIDMYLRIAPELYLKRLVVGGFDRVFEINRNFRNEGVSPRHNPEFTMMELYMAYADYRDLIELTEELFRTLTQDVLGSTIVKYGDEEFDFGKPFEKLTMKEAICKYRPETNMADLDDMDKAVAIAQSIGIKIEKSWGLGRVQCEIFEEVAESHLIQPTFIIEYPAEVSPLARRNDDNPFITDRFEFFIGGREIGNGFSELNDAQDQAERFEEQVRQKEAGDDEAMFFDHDYITALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPGK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.