PharMolix/UniProtQA huggingface dataset:
Protein: RS11_NEIM0
Sequence: MAKANTASRVRKKVRKTVSEGIVHVHASFNNTIITITDRQGNALSWATSGGAGFKGSRKSTPFAAQVAAEAAGKVAQEYGVKNLEVRIKGPGPGRESSVRALNALGFKITSITDVTPLPHNGCRPPKKRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: H1_ECHCR
Sequence: AASPQKRAASPRKSPKKSPRKSPKKKSPRKRKARSAAHPPVIDMITAAIAAQKERRGSSVAKIQSYIAAKYRCDINALNPHIRRALKNQVKSGALKQVSGVGATGRFRVGAVKRSAASANKLKATREKARARAKAKKAKAAARRKAAAAKRKAAAAKRRAAKKARKAKAKP
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1, gonadal.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PHOSP_MEASC
Sequence: MAEEQARHVKNGLECIRALKAEPIGSLAVEEAMAAWSEISDNPGQDRATCKEEEAGSSGLSKPCLSAIGSTEGGAPRIRGQGSGESDDDAETLGIPSRNLQASSTGLQCYHVYDHSGEAVKGIQDADSIMVQSGLDGDSTLSGGDDESENSDVDIGEPDTEGYAITDRGSAPISMGFRASDVETAEGGEIHELLKLQSRGNNFPKLGKTLNVPPPPNPSRASTSETPIKKGTDARLASFGTEIASLLTGGATQCARKSPSEPSGPGAPAGNVPECVSNAALIQEWTPESGTTISPRSQNNEEGGDYYDDELFSDVQDIKTALAKIHEDNQKIISKLESLLLLKGEVESIKKQINRQNISISTLEGHLSSIMIAIPGLGKDPNDPTADVELNPDLKPIIGRDSGRALAEVLKKPVASRQLQGMTNGRTSSRGQLLKEFQLKPIGKKVSSAVGFVPDTGPASRSVIRSIIKSSRLEEDRKRYLMTLLDDIKGANDLAKFHQMLMKIIMK
What is the function of this protein?
Essential component of the RNA polymerase and the nascent chain assembly complex.  Also required during RNA synthesis.
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus P protein family.
Protein: HIS6_SALPK
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIRSIDDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWFDDATGKYHVNQYTGDENRTRVTQWETLDWVQEVQQRGAGEIVLNMMNQDGVRNGYDLTQLKKVRDVCRVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLAGQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_STRPJ
Sequence: MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYLAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAFHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXAC_ALKCK
Sequence: MISTGKAFIHENFMLQNKTAETLYHTYAKTLPIIDYHCHVPPQEIAENRQFNNISEIWLHGDHYKWRAMRAVGVEETFITGDGDDKEKFLKWAETVPYTMGNPLYHWTHLELKRYFGIDELLSSETAEAIWSATKEQLAAPERSVQGIIKESNVKVICTTDDPSDHLEAHQQIRKEGACQAAVYPAFRPDKALVASAPSFVPYLETLGAAAEVDISSLRSLLEALEKRATFFAEEGCVLSDHGLRTLPFVDTTEKEAEAAFQKALNQETLTPQEEEKYQTYVLLFLARLYNKLGWTMQFHLGALRNNNSRMVEQVGPDSGFDSMADDRFAESLNRFLNELERTNELPKTILYTLNPIFNEVIATTIGNFQGGGIPGKIQFGSGWWFNDTKDGMEKQMTDLANNGLLSLFVGMLTDSRSFLSYTRHEYFRRILCNRIGEWVERGEWPADEKWLGKVVEDISYYNAKRYFAFPK
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: WBP2_MOUSE
Sequence: MALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKNVPEAFKGTKKGTVYLTPYRVIFLSKGKDAMQSFMMPFYLMKDCEIKQPVFGANFIKGIVKAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPNGAYGYPYMPSGAYVFPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGPSAPATPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ
What is the function of this protein?
Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation.  In presence of estrogen, binds to ESR1-responsive promoters.  Required for YAP1 coactivation function on PGR activity.  Synergizes with WBP2 in enhancing PGR activity (By similarity).  Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR (PubMed:26881968).
What are the official names of this protein?
WW domain-binding protein 2, WBP-2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus when phosphorylated.
Protein: LGT_STRAW
Sequence: MELAYIPSPARGVLYLGPIPLRGYAFCIIIGVFVAVWLGNKRWVARGGRPGTVADIAVWAVPFGLVGGRLYHVITDYELYFSEGRDWVDAFKIWEGGLGIWGAIALGAVGAWIGCRRRGIPLPAWADAVAPGIAFAQAFGRWGNWFNQELYGRETHVPWALHITSSTDGRVPGYYHPTFLYESLWCVGVGFLVIWADRRFKLGHGRAFALYVAAYCVGRAWIEYMRVDDAHHILGVRLNDWTAIAVFLLAVLYIVLSSRKRPGREEIVEPGASDTGTGADDPVDLGKDEDKATTDKATATDTSTTTDKSTDRGKNEDENEGEDAEPSEKTESAAESAKKV
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4125_CYAP4
Sequence: MDIKLINIGFGNIVSAHRVIAIVSPESSPIKRIITEAREKGQLIDATYGRRTRAVIIADSGHVILSAIQPETVANRFLLSRDVHDSSSSPC
What are the official names of this protein?
Putative regulatory protein Cyan7425_4125.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: TVP38_NEOFI
Sequence: MPADYTSTARALSLPMSPAESLSPAEEDTQPLWSHLASSRRNTASPSARESTGLRDQVVNQATKMLRRTKKTWRRLTFWQRIGAIGAALLAILLGLAFMIFTGQVFFWLGPVAEKWEQSWLAFFVLWLCVFFVSFPPLVGWSTFGTIAGFIFGIWKGWILYATATVLGSTCSFIVSRTILSKFVNRMMERDKRFAALALTLKYDGLKLLCMIRLCPLPYSVCNGAVSTFPTVHPLMYGLATALITPKLLVPAFIGSRIRILSEKNEEMSAGSKAVNICSIILTIGIGIFTGWYIYRRTLARAKELEAKERADIRRSLQADHAAHHPHGSFSEDPDVNTAATTLARDEEERIGFNDFDDDNVDLVIDDESGSENSPNLTKKQFQGPYRDEFTDNDSDVFGDGDGPDSQMFRLHTHVRSG
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking and spindle migration.
What are the official names of this protein?
Golgi apparatus membrane protein tvp38.
What is the protein family that this protein belongs to?
Belongs to the TVP38/TMEM64 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: Y2241_LISW6
Sequence: MSVLFTILLMAVIGGFIGAMTNYIAIRMLFRPYKALYLFNKRVPFTPGLIPKRRDELAEHIGKVVVSHLLTEDAIRARLLEENLQKEITETVAKMFHEKMQLETTPNELLHQLGYENAEGRSISWLETVLEKEINHFLTIKKTSQMNELIPVMLEKELETKLPHVTERITSKLTLFIASEEGKLQIKMMLQKFFEEHGKMGSMARMFINVESFSEKIQQEGAKLINQEDTKNLINQLLTTEWKNFEAKELQELIPTEKQAHLAEQLTSEIIQAFPHDKIFNQPVQVILRDYEVMIKSKIIPFAVERMLDFVATHSADIVERMDLAKLVETQIATFSLQEIEKLVVEISGRELKMITYLGGILGGFIGVIQGILAIWI
What are the official names of this protein?
UPF0754 membrane protein lwe2241.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFG_THET8
Sequence: MAVKVEYDLKRLRNIGIAAHIDAGKTTTTERILYYTGRIHKIGEVHEGAATMDFMEQERERGITITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSSQGVEPQSETVWRQAEKYKVPRIAFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIGREDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIMLKYLEGEEPTEEELVAAIRKGTIDLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLDIPPIKGTTPEGEVVEIHPDPNGPLAALAFKIMADPYVGRLTFIRVYSGTLTSGSYVYNTTKGRKERVARLLRMHANHREEVEELKAGDLGAVVGLKETITGDTLVGEDAPRVILESIEVPEPVIDVAIEPKTKADQEKLSQALARLAEEDPTFRVSTHPETGQTIISGMGELHLEIIVDRLKREFKVDANVGKPQVAYRETITKPVDVEGKFIRQTGGRGQYGHVKIKVEPLPRGSGFEFVNAIVGGVIPKEYIPAVQKGIEEAMQSGPLIGFPVVDIKVTLYDGSYHEVDSSEMAFKIAGSMAIKEAVQKGDPVILEPIMRVEVTTPEEYMGDVIGDLNARRGQILGMEPRGNAQVIRAFVPLAEMFGYATDLRSKTQGRGSFVMFFDHYQEVPKQVQEKLIKGQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_WOLTR
Sequence: MGIKFLNPVTPSSRGTVLVSKIGLSRGKPEKSLAFGKKSSGGRNNNGRITIRHKGGGHKKKYRIIDFKRNRNDQGVVEKIEYDPNRSGFLALVSYKCDDTKSYILAPQGIKPGDIVMSGSGIDILPGNCLPLKGIPIGSFVHGVELKPGSGAVIARAAGCYAQVVGRDGNYVLLRLRSGQVRLVLSSCKATIGVVSNPDRKNRKLGKAGRSRWLGVRPTVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGVATKGKKTRKKNKFSDKYIKQLKG
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RSMH_RHOBA
Sequence: MTASQPLDQADQDSESSSAGSSAAETEHVSVMPNEIVQWVREINPTTIIDGTYGGGGHTRLLAEVLADAGSDSDTPRVIAIDRDPAVVRRDEQKSWIKDDPRIELFLGSYESSPKALDALDLTHADALVLDLGLSSDQLADRNRGFTFTIDDAELDLRFDPENGVPAHRWLQQHSEKEIADAIYRFGEERFSRRIAKQIFLRARERNPVTKVGELVEICRRCVPRSRNHDIHPATRTFQALRIAVNDELGGLTRTLQSAPDWIAPGGRVAVISFHSLEDRIVKNAFREDHRWEILTKKPLRPTDEEVQANPRSRSAKLRVAKRVE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3P_COCP7
Sequence: MVVKVGINGFGRIGRIVFRNAVEHPEVEIVAVNDPFIETHYAAYMLKYDSTHGRFKGDVKFSENGLDVDGKHVRFYQERDPANIPWAETGADYVIESTGVFTTTEKASAHLKGGAKKVIISAPSADAPMFVMGVNNETYKSDIKVLSNASCTTNCLAPLAKVVNDNFGLVEGLMTTVHSYTATQKTVDGPSSKDWRGGRTAAQNIIPSSTGAAKAVGKVIPSLNGKLTGMSMRVPTSNVSVVDLTCRTDKSVTYDQIKEAMKKASANELKGIMSYSEDALVSSDLNGDPHSCIFDATAGIALNDHFIKLVAWYDNEWGYSRRVIDLIAYIAGVDAGK
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_HELPS
Sequence: MKEILNALYHQKDLNDGEVKKLFTLIINEKVSPAQLGAVLCALKIKGESFKEISVAATTLLEHAPKPFDSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLSMAKHGSRSVSSHSGSADLLENLGVNIEMNPTQLENCFKQTHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPLINPLRPKIQLLGVYEKSLCKTMALALKALGVKRAMVVNGGGTDEIVLHDTTHACELKNNGILEYDLSAKDFDLPPYDLKELQIKNAQESVQACLDILENKGKDSHTMVVVANVASLLYLSHKAKDLKEGVGMTLEHLKTKVPYTHLQKIIRLSHA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PEMT2_DICDI
Sequence: MEKGLSSDLIIAFVAIVLHVVNYNVTAQFEYKTRYFTKLIGRNAIYYYAVFLIISALIRDHFINVAVLSDKDSIILFPTEIANMIGDSCFIFGILLNIWTLKALGIKGMYNGDSFGHIMDSPVTGGPYQFFSDPQYVGTTIAALGVAIRNQSIYGFLCTILVGVVFYISATFVETPHLKNIYSNRSYSKINFKNLKSLKN
What is the function of this protein?
Catalyzes the three sequential steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME), PMME to phosphatidyldimethylethanolamine (PDME), and PDME to phosphatidylcholine (PC).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase B, PEAMT, PEMT, Phospholipid methyltransferase B, PLMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Protein: RUVC_YERPN
Sequence: MAIVLGIDPGSRVTGYGVIRQQGRQLTYLGSGCIRTVVDDMPTRLKLIYAGVTEIITQFQPDFFAIEQVFMAKNPDSALKLGQARGAAIVAAVNLNLPVSEYAARQVKQTVVGTGAAEKSQVQHMVRSLLKLPANPQADAADALAIAITHCHLSQNTLRLGNDQMTLSRGRIR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CHMP3_BOVIN
Sequence: MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCVVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEAAEMEIDRILFEITAGALGKAPSKVTDALPEPEPLGAMAASEDEEEEEEALEAMQSRLATLRS
What is the function of this protein?
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (lentiviruses).  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.  Selectively binds to phosphatidylinositol 3,5-bisphosphate PtdIns(3,5)P2 and PtdIns(3,4)P2 in preference to other phosphoinositides tested.  Involved in late stages of cytokinesis.  Plays a role in endosomal sorting/trafficking of EGF receptor (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 3, Chromatin-modifying protein 3, Vacuolar protein sorting-associated protein 24.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Lipid-anchor. Endosome. Late endosome membrane. Note=Localizes to the midbody of dividing cells.
Protein: DTD_ACIBT
Sequence: MRALIQRVLEAKVEVDGQTTGEIKKGLLVFLGIGRDDTLATGQKLIDKILKYRIFDDEQGKMGWNVSQANGGILLVSQFTLMAQTQKGLRPDFGPAMPPSDAKALYEQLVEYTRSQFENVQTGIFAADMKVHLINDGPVTFNLEVEA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNSP1_BOARA
Sequence: MAFLKKSLFLVLFLGIVSLSICEEEKREGEEEEKQEEENEELSEEELRERRAWLDKLKSLGKVVGKVALGVAQNYLNPQQ
What is the function of this protein?
Has antibacterial activity against the Gram-negative bacteria E. coli ATCC 25922 (MIC=5 uM), P. aeruginosa ATCC 27853 (MIC=10 uM) and X. citri (MIC< 2 uM), and the Gram-positive bacterium S. aureus ATCC 29313 (MIC=20 uM).  Does not have hemolytic activity against human erythrocytes.
What are the official names of this protein?
Raniseptin-1, Rsp-1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
Protein: RS17_PYRFU
Sequence: MMRDIGLRVQPPAEKCDDPKCPWHGNLKIHGRVFEGIVVSDKPRKTVTVERQYYFYLNKYERYELRRSKIHAHNPPCINAKVGDKVLIAETRPLSKTKHFVVVAVLERAEERR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17, Small ribosomal subunit protein uS17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SLEL_DROME
Sequence: MRTIFNAKIGDAAYIQDELSSSLSSSVASKFKEFSKRKRISDSFSDLSEELERIGLRQMRKRIKLEKSFERTPKKKVQTKKHLPPVRKKDSVKRRRIIIASPSDEEHDGKVQTNDDSSENKTEKPKNQSNCSSNASKLSEAAQLLNVSEEKSSISETELERSRQVALNELNKSERFNKTETQLDISVMEVDSSDHDEEEKTEKVGAKNNRSLYEIVDSDDEEEQDQDQSDAAKPAESENHSEIKKSTSFMDQMSGAKGNKSVYEIMDSYETEDPKEAGKNEESDKDKPAENGKSDKDKQAETEMSDEDKPSEIKSPSTIKKSIISTADEEALLAELASSDLSHLEKMFNPLQKSRRQSLHVPSPELAAKNPKLRRRSERVEVGNDFCPSQSFVDMVAEKKRQKNKRKRLSKSLSGAPEDLEEMEIKHERKRLKSSHGASTDSMEEDNENETMTVAEEHHSDGEVSNGEVPIEEKPTTSSEKPSASELPEEGNSAPPALKKDVKRLQAARQAVSHAVNLLAPPKATEAEPRTLSRKLSPQPPVVDKKSAKQKKKGKKKQKPQEASPLKSSDEENHGHRIRTNAGYVTVVDEPPTKVPIIELIKTSSGMVRVEPCTPKQKYFRELPPTPKMHGFREEPGPSGMSRKRAKHAAPKVEHNSAKQAALRFKEQIFARRS
What are the official names of this protein?
Slender lobes-like protein.
Protein: RL24_STAA9
Sequence: MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKHQKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIKSNN
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL25_VIBVY
Sequence: MKFEAVVRTELGKGASRRLRLAGQFPAVVYGGEAAPVAVALNHDDIVNQMDKPEFYEAITLVIGGEEVKVKPQDVQRHAFKPKVEHMDFIRI
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: FEN_PYRHO
Sequence: MGVPIGDLVPRKEIDLENLYGKKIAIDALNAIYQFLSTIRQRDGTPLMDSKGRITSHLSGLFYRTINLMEAGIKPAYVFDGKPPEFKRKELEKRREAREEAELKWKEALAKGNLEEARKYAQRATKVNEMLIEDAKKLLQLMGIPIIQAPSEGEAQAAYMASKGDVYASASQDYDSLLFGAPRLIRNLTITGKRKMPGKDVYVEIKPELVVLDEVLKELKITREKLIELAILVGTDYNPGGVKGIGPKKALEIVRYSRDPLAKFQRQSDVDLYAIKEFFLNPPVTNEYSLSWKEPDEEGILKFLCDEHNFSEERVKNGIERLKKAIKAGRQSTLESWFVKKKP
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: RS5_MYCBP
Sequence: MAEQPAGQAGTTDNRDARGDREGRRRDSGRGSRERDGEKSNYLERVVAINRVSKVVKGGRRFSFTALVIVGDGNGMVGVGYGKAKEVPAAIAKGVEEARKSFFRVPLIGGTITHPVQGEAAAGVVLLRPASPGTGVIAGGAARAVLECAGVHDILAKSLGSDNAINVVHATVAALKLLQRPEEVAARRGLPIEDVAPAGMLKARRKSEALAASVLPDRTI
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SDHF3_EMENI
Sequence: MRIFTRLLYAAPSNMGSAASLSEALALLPPIPLYRRILRVHRKKLDPEMRILGDSYVKSEFRAHRGTENPLHIIGFLTEWQLYAQKLEGDSWIGEKLDQGKLDKMSDQQLGQLYELMQTIQNKDGKGEGEGESEK
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  May act together with SDHAF1.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 3, mitochondrial, SDH assembly factor 3, SDHAF3.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.