PharMolix/UniProtQA huggingface dataset:
Protein: CP2CF_RABIT
Sequence: LGILFSNANTWKEMRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNASPCDPTFILGCAPCNVICSIIFHNRFDYKDEHFLKLMEKFNENVRILSSPWLQICNNFPVLTDYLPGIHNTLVKNIEYTKNFIMEKVKEHQKSLDVNNPRDFIDCFLIKMDQENHLEFTLESLVTTVSDLFGAGTETTSTTLSISLLLLLKHPEVAAKVQEEIERVIGRHRSPCMQDRSRMPYTDAVIHEIQRYIDLIPINLPHAVTRDIKFRNYFIPKGMNIITSLTSVLHDEKEFPNPKVFDPGHFLDESGNFKKSDYFMPFSAGKRMCVGEGLARMELFLFLTSILQNFKLQSLVEPKDLDITAVVNGFASVPPAYQLCFSPV
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 2C15, CYPIIC15, Cytochrome P450 B32-3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TTCA_PSEE4
Sequence: MGTLSVNQNKLQKRLRRLAGEAITDYNMIEDGDKVMVCLSGGKDSYTMLDVLLHLQKVAPIKFDIVAVNMDQKQPGFPEHVLPAYLKELGVEYHIVEKDTYSVVKELVPEGKTTCSLCSRLRRGTLYTFADEIGATKMALGHHRDDIVETFFLNMFFNGALKGMPPKLRADDGRNVVIRPLAYCSEKDIQAYSDMKEFPIIPCNLCGSQENLQRQVVKDMLVEWERKHPGRTESIFRALQNVAPSQLADRNLFDFTSLKIDESATPRFLDVLNI
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITR3_CUCMC
Sequence: QRMCPKILMKCKQDSDCLLDCVCLKEGFCG
What is the function of this protein?
Inhibits lysyl endopeptidase and trypsin.
What are the official names of this protein?
Trypsin inhibitor 3, CMCTI-III, Trypsin inhibitor III.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURI_ALIB4
Sequence: MKVGVFDSGLGGLTVLKSILKVLKNAEIFYIADTAYAPYGEKDSALILKRCEDITNYLLKEYKIDALIVACNTATSAAIKHLRDNFSSLIVIGTEPGIKPAILNTKSSNIGILATPSTLKSDKYQLLVNELSSIKKVNLFEQACPGLAMQIEKGEINTLTTYKMLEEWLIPMKEANVDTIVLGCTHYPLISQTIKKIMGEDITLIQTGDAIAKRLLSLSEEKGHKNIGDLKVTVLHTGLINLDMIENILENKNIEVRKCEI
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: RL2_HYDS0
Sequence: MGVRKLKPVTNGQRHAILYDYSELTRREPEKSLTYYYKRALGRSRQQGKITSRWKGAGNKIRYRLIDFKRDKSLIPAKVYSIEYDPFRSARIVLLHYKDGEKKYILWPDKLNVGDTVVSISYEDAIKGKELPDIKPGNAMPLRFIPVGTFIHNIELNPGRGAKLVRAAGLSAQVIGKIEGYAQVRLPSGEVRLINDKCMATIGVVGLAEHELVKLGKAGRSRWLGMRPNVRGTAMNPVDHPHGGGEGKTKGKHPESPWGWKTKGYKTKRGKRYSDRFIISKRNAGGKV
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CLUA1_HUMAN
Sequence: MSFRDLRNFTEMMRALGYPRHISMENFRTPNFGLVSEVLLWLVKRYEPQTDIPPDVDTEQDRVFFIKAIAQFMATKAHIKLNTKKLYQADGYAVKELLKITSVLYNAMKTKGMEGSEIVEEDVNKFKFDLGSKIADLKAARQLASEITSKGASLYDLLGMEVELREMRTEAIARPLEINETEKVMRIAIKEILTQVQKTKDLLNNVASDEANLEAKIEKRKLELERNRKRLETLQSVRPCFMDEYEKTEEELQKQYDTYLEKFQNLTYLEQQLEDHHRMEQERFEEAKNTLCLIQNKLKEEEKRLLKSGSNDDSDIDIQEDDESDSELEERRLPKPQTAMEMLMQGRPGKRIVGTMQGGDSDDNEDSEESEIDMEDDDDEDDDLEDESISLSPTKPNRRVRKSEPLDESDNDF
What is the function of this protein?
Required for cilia biogenesis.  Appears to function within the multiple intraflagellar transport complex B (IFT-B).  Key regulator of hedgehog signaling.
What are the official names of this protein?
Clusterin-associated protein 1, Qilin.
What is the protein family that this protein belongs to?
Belongs to the CLUAP1 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Nucleus.
Protein: PANB_SALA4
Sequence: MKPTTISLLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQACENAAIVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAGQMLLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAEAGDMRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS5_RHILO
Sequence: MRVAIIDYGSGNLRSATKAFERAAREGGISAEIDLTADADRVRTADRIVLPGVGAYADCAAGLRAVDGMWEAVEDVAIAQSRPFLGICVGMQLMSERGLEKTVTHGFGWISGDVKEITPTDPALKIPQIGWNTIELRRQHPLFAGIPTGPEGLHAYFVHSYHLDAKKPDEILAVADYGGPVTAAVARDNLVGTQFHPEKSQALGLALITNFLRWRP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG74_BPML5
Sequence: MEFPFGGMTFQCLHLTSLDKVQLWFRWRSRDWQFGHAKPIPEGMDAASVANLMRQFIVGEISHDEYNRLLPN
What are the official names of this protein?
Gene 74 protein, Gp74.
Protein: HBE2_BOVIN
Sequence: MVHFTTEENVAVASLWAKVNVEVVGGESLARLLIVCPWTQRFFDSFGNLYSESAIMGNPKVKVYGRKVLNSFGNAIKHMDDLKGTFADLSELHCDKLHVDPENFRLLGNMILIVLATHFSKEFTPQMQAAWQKLTNAVANALTHKYH
What is the function of this protein?
Hemoglobin epsilon chain is a beta-type chain found in early embryos.
What are the official names of this protein?
Hemoglobin subunit epsilon-2, Epsilon-2-globin, Hemoglobin epsilon-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RPOB_MYCSS
Sequence: MLEGCILAVSSQSKSAKAITNNSVPGAPNRISFAKLREPLEVPGLLDVQTESFDWLIGADSWRQRATARGDVNPTGGLEEVLTELSPIEDFSGSMSLSFSDPRFDEVKAPVDECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDESIDKSTEKTLHSVKVIPGRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTNEQITERFGFSEIMMSTLEKDNTAGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLNTDKPITSSTLTEEDVVATIEYLVRLHQGDTVMTVPGGVEVPVEVDDIDHFGNRRLRTVGELIQNQIRVGLSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHSSHYGRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVENGVVTDQIDYLTADEEDRHVVAQANSPLDDEGHFTEDRVLVRRKGGEVEFVSATEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGDVVVSEKAGVVEEVSADYITVMADDGTRHTYRMRKFARSNHGTCANQRPIVDAGQRVEAGQVVADGPCTQNGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSREDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPVEDMPFLPDGTPVDIILNTHGVPRRMNIGQILETHLGWVAKAGWNINVAGADGVPDWAEKLPEELYSAPSDSIVATPVFDGARENELSGLLASTLPNRDGDVMVNEDGKAELFDGRSGEPFPYPVTVGYMYILKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIEMRDGDDEDLERAAANLGINLSRNESASVEDLA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: TGFA_RAT
Sequence: MVPAAGQLALLALGILVAVCQALENSTSPLSDSPVAAAVVSHFNKCPDSHTQYCFHGTCRFLVQEEKPACVCHSGYVGVRCEHADLLAVVAASQKKQAITALVVVSIVALAVLIITCVLIHCCQVRKHCEWCRALVCRHEKPSALLKGRTACCHSETVV
What is the function of this protein?
TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
What are the official names of this protein?
Protransforming growth factor alpha.
What are the subcellular locations of this protein?
[Transforming growth factor alpha]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Protransforming growth factor alpha]: Cell membrane; Single-pass type I membrane protein.
Protein: DDL_ACIET
Sequence: MSQNDPKIDVKALGKVAVLMGGTSAEREVSLMSGGGVLQALRSRGVDAHAFDPAHSDLSELKAHGYSRCFIALHGRHGEDGTVQGALELLGIPYTGPGVMASSIAMDKIMTKRIWRADGLPTPDWRLVSSSAETAQAFQELGAPMIVKPSREGSTIGLTKVTSLGQCEQAYRLAAQHDPEVLCEQFIDGDETTCPILGQGAEARALPVIRIEAPQGNYDYQNKYFTDVTQYHCPSGLPEAEEREIQRIVVQAYRTLGCRGWARADIMIRASDRKPFLLEINTSPGMTGHSLVPMSANASGISYPDLCLRILASASLDALQGRAGAAGGREPV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CGR1_KLULA
Sequence: MSDNTAEQQDIQIKGKPVSGRTWKVEKEPLRAKNRVVKNKKLTSWELKKQKRLEDQQFKEKVRALKEEKKAEKDAVIQALKERRAKKEEQERYDRLAAKMHAKKVDRLRRREKRNKALKER
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein CGR1.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DSRB_ECO7I
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: TM6S1_HUMAN
Sequence: MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPRDPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALDCPSELCRLYTQFQEPYLKDPAAYPKIQMLAYMFYSVPYFVTALYGLVVPGCSWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFFIKTKAEEKVE
What is the function of this protein?
May function as sterol isomerase.
What are the official names of this protein?
Transmembrane 6 superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the TM6SF family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: SSUA_BACSU
Sequence: MKKGLIVLVAVIFLLAGCGANGASGDHKQLKEIRIGIQQSLSPLLIAKEKGWFEDAFEKEGIKVKWVEFQSGPPQFEGLAADKLDFSQVGNSPVIAGQAAGIDFKEIGLSQDGLKANGILVNQNSGIQDVKGLKGKKIAVAKGSSGFDFLYKALDQVGLSANDVTIIQLQPDEAASAFENGSVDAWSIWEPYLSLETMKHGAKILVNGESTDLYSPGFTLVRTKFSEEHPDEVVRFLKVFNKAVVWQKEHLDEAADLYSDIKDLDKKVVENVLKNTEPLNEIISDDIVKAQQETADFQFRTKAIDKKIDVKDVVDNTFIKKALEEHSSGGDQ
What is the function of this protein?
Part of a binding-protein-dependent transport system for aliphatic sulfonates.  Putative binding protein.
What are the official names of this protein?
Putative aliphatic sulfonates-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein SsuA/TauA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TM223_MOUSE
Sequence: MVASVPLRNVSHLLSVLRSQNVPRYLQNGVPRDVLLFRHERGRFFAILGLFCAGQGIFWTSLAVAALSRPLSRVPAEAPNRSYQDLRSALWRYGLAVGCGTMGVLVLGAGLLYSLRSVRSVMLLAGGQQVTLTTYAPFGLGTCFTVPLNQISCMAHRGEVPAMLPLKVKGRRFYFLLDKAGHFPNTQLFDNTVGAYRSL
What is the function of this protein?
Mitochondrial ribosome-associated protein involved in the first steps of cytochrome c oxidase complex (complex IV) biogenesis.  Stimulates the translation of MT-CO1 mRNA and is a constituent of early MT-CO1 assembly intermediates.
What are the official names of this protein?
Transmembrane protein 223.
What is the protein family that this protein belongs to?
Belongs to the TMEM223 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YD209_YEAST
Sequence: MNDGQFLFQRNDPIILYTFLLKSNYTVFRSIDERLCDFVFYIDHFLNKRISYRIPILIRNNNTNILNNCPSSFPPLVDLVGHRLVAAEDNPVAVDLVDNNLVVVDLVDNNLAVGVLVGSNLVVGSLVFALLTCFEDG
What are the official names of this protein?
Uncharacterized protein YDR209C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EPSE_RALSO
Sequence: MQKTAPRPPSARISFLSASVLGLGAAVASRGAVFLVNIMLAHSLTVHDFGLFSYAYVTALNLGLFLATGVSQAAGHVLPLTEDPERRRRQLCAFIVLLVALIAVAATALYLSATSISIAAFGSAQGGEALRMAAIVLIATAFTQALQAFLYAMHEHRASASVSIGAALLLLAMLWTMGPIRQPVVALVIFLAINAGAAASQLVILGRTTQNQRGPWRTGRQELRLAFKHALPSVLTTSMGAPVHWICLSMLAAMTDGAHQLALFSVAFQWYIAITFIPATLGNLALPFLARNTGATEAMVRQRFRSALLFGGGLSLALGCMAFLLAGQIFAWLYPAAYGSAAASMRSLAVAAALCGISVLLQQRIAAAGKFWRNFAMAAVYSVIYVAAAYLALRLGYGAPSIGLAMSAAYCCLILFQTLTLQSDSGAAIRLGRSFS
What is the function of this protein?
Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor.  May play a role in export of EPS I or its intermediates across the membranes (By similarity).
What are the official names of this protein?
EPS I polysaccharide export inner membrane protein EpsE.
What is the protein family that this protein belongs to?
To E.coli bicyclomycin resistance protein (BCR).
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AK1C4_HUMAN
Sequence: MDPKYQRVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDFLMDHPDYPFSDEY
What is the function of this protein?
Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids.  Liver specific enzyme that acts as NAD(P)(H)-dependent 3-, 17- and 20-ketosteroid reductase on the steroid nucleus and side chain (PubMed:14672942, PubMed:10998348, PubMed:7650035, PubMed:1530633, PubMed:11158055, PubMed:10634139, PubMed:19218247).  Displays the ability to catalyze both oxidation and reduction in vitro, but most probably acts as a reductase in vivo since the oxidase activity measured in vitro is inhibited by physiological concentration of NADPH (PubMed:14672942).  Acts preferentially as a 3-alpha-hydroxysteroid dehydrogenase (HSD) with a subsidiary 3-beta-HSD activity (PubMed:14672942).  Catalyzes efficiently the transformation of the potent androgen 5-alpha-dihydrotestosterone (5alpha-DHT or 17beta-hydroxy-5alpha-androstan-3-one) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol) (PubMed:11158055, PubMed:10998348, PubMed:14672942).  Catalyzes the reduction of estrone into 17beta-estradiol but with low efficiency (PubMed:14672942).  Metabolizes a broad spectrum of natural and synthetic therapeutic steroid and plays an important role in metabolism of androgens, estrogens, progestereone and conjugated steroids (PubMed:10998348, PubMed:14672942, PubMed:19218247).  Catalyzes the biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leading to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route (PubMed:2427522).
What are the official names of this protein?
Aldo-keto reductase family 1 member C4, 3-alpha-hydroxysteroid dehydrogenase type I, 3-alpha-HSD1, 3alpha-hydroxysteroid 3-dehydrogenase, Chlordecone reductase, CDR, Dihydrodiol dehydrogenase 4, DD-4, DD4, HAKRA.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: GLMU_HAMD5
Sequence: MSKKVMSVVILAAGKGTRMCSNLPKVLHLLAGKPMVQHVINTANQLDCTRIHLVYGHGGALLKEKLNNEKLNWILQEEQWGTGHALQKAIPYFSEDENILVLYGDVPLIEVDTLNRLLLAKPHGGISLLTARVDNPRGYGRIIRKNDDISGIVECKEATEIQKKINEINTGIMAINSSDLKKWLKQLKNDNHQNEFYLTDIIKMAYQENRKIIGIQPAHLNEIEGINDGLQLARLERLFQKQQAEKLLLSGVRILDPARFDLRGQLICGSDVVIDTNVIIEGEVTLGDRVQIRTGCLLKNCRIGDDSQINAYTVIEGSFLDKNCVVGPFARLRPGSELSEKVHVGNFVEIKKSSLGQGSKAGHLSYLGDAEIGSGVNIGAGTITCNYDGVNKHKTQIGDYVFVGSHTQFIAPVTVGDHATIGAGTTVTLNVPENELGLSRVKQKNIQGWKRPKKT
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F221A_XENTR
Sequence: MEKLQFQGGARAIDEYAEYRRIVGDDDGGKLFTPEEYEEYKKTVLPMRLQNRLYVSWRSPTGMDCKLVGPETPCFCTHRYKQHKTDFQELPKERPLLLPCRVSKCACKSFHYIPLNGSRPIRCRCKHFADEHSVAGTYHCTQCTKCSGFHSSFTCGCSQPAYTHDTVVETKEERLAQGKPVGHDVPFAAMGGLTGFSSLAEGYMRLDESGAGAPSTSFLESSESGTSHPFLKMYYQPIKVQAVSEPSGIVTQVSNMRISEDDDMAYFERRYQERLLKEKEQKRQKNSKPPTTNRP
What are the official names of this protein?
Protein FAM221A.
What is the protein family that this protein belongs to?
Belongs to the FAM221 family.
Protein: RL32_PIG
Sequence: MAALRPLVKPKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILMPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNPNARLRSEENE
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL32 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_STRPG
Sequence: MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSAFFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITDLEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGFIKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVEALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPTFVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDELGMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT5A_CONSP
Sequence: MRCLPVFVILLLLIASAPSVDAQLKTKDDVPLASFHDNAKGTQHKRIINWCCLIFYQCC
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (PubMed:35940316).  This peptide inhibits the cardiac sodium channel hNav1. 5/SCN5A (33% inhibition at 200 nM, 50% at 400 nM, and 55% at 600 nM) (PubMed:35940316).  Does not interfere with the voltage-dependence of activation, but affects the voltage-dependence of inactivation of hNav1. 5 (PubMed:35940316).  In vivo, intracranial injection into 9-day-old mice causes transient symptoms, including extension of the body and clockwise and counter-clockwise turns, that last 3 to 4 minutes (PubMed:16297502).  Intracranial injection into 16-day-old mice, causes transient symptoms, including agitated breathing and occasional turning followed by scratching and grooming behavior, that last for 15-19 minutes (PubMed:16297502).
What are the official names of this protein?
Mu-conotoxin SrVA, Conotoxin sr5a, Sr5.1, Sr5.2, Sr5.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SIGE_SALDU
Sequence: MESLLNRLYAALGLDAPEDEPLLIIDDGIQVYFNESDHTLEMCCPFMPLPDDILTLQHFLRLNYASAVTIGADADNTALVALYRLPQTSTEEEALTGFELFISNVKQLKEHYA
What is the function of this protein?
Molecular chaperone required for SopB/SigD stabilization and secretion.
What are the official names of this protein?
Chaperone protein SigE.
What is the protein family that this protein belongs to?
Belongs to the IpgE/SigE chaperone family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOT7_HUMAN
Sequence: MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLEMDLAKNEHRVHVQMEPV
What is the function of this protein?
Proton-linked monocarboxylate transporter.  Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
What are the official names of this protein?
Monocarboxylate transporter 7, MCT 7, Monocarboxylate transporter 6, MCT 6, Solute carrier family 16 member 6.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS10_PYRFU
Sequence: MQKARIKIASTNVRSLDEVANQIKQIAERTGVRMSGPIPLPTKRIRITTRKSPDGEGSATFDRWELRVHKRLIDIEADERAMRQIMRIRVPEDVTIEIELIS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: Y1808_RHOCS
Sequence: MAGHSQFKNIMHRKGAQDAKRAKKFNKLAREITVSAKAGLPDPASNPRLRAAIQAARAENMPKDRIERAIKQGTPGADGANYEEVRYEGYGPGGVALIVEALTDNRNRTASEVRTAFTKFGGTLGETNSVSFMFNRIGQVVYPASVADADTVLEAAIEAGADDVQSDEGGHYISTAVDSLGEVRDALETRFGPPESAKLTWQPQNTVPVAAEDAAQSLMKLLDMLDDNDDVQTVLGNFDIPQDLLDKLNG
What are the official names of this protein?
Probable transcriptional regulatory protein RC1_1808.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.