PharMolix/UniProtQA huggingface dataset:
Protein: PVIP_PEA
Sequence: PTADAIAAKKMENGKAAIDFPDQSVIRRVSSADRISLQDIARERVDVICDRMHRLPDEFLDELKNGLRAILEGGNGSQHRDEFFILQKLVQSRSDLTAKTLIRAHRVQLEILVSINTGIQGFLHPSISLSQTSLIEIFLYKRCRNIACQNQLPADECSXDTCTNNNGFCNLCMCVICSKFDFEVNTCRWIGCDLXSHWTHTDCAIREQLICMGPSVKSGSGPSEMVFRCQACSXTSXLLGWVKDVFQHCAPSWDGDALIRELDFVSRIFHGSKDQRGMNLFWKCDDLKEKLKSRKMDSKAACRAILMVFQELDLDNSKSLENAESGRLIAPQEACNRIAEVVQEAIRKMEFVADEKMRMFKKARIAVEACDRELADKAREAGDLKVERQKKKSQIEELERIVRLKNAEADMFQLKANEAKREAERLQRIALAKSDKSEEEYTSNYLKQKLSEAEAEKQYLYEKIKLQESSRLSQSSGDPSSMLMYSKIHDLLYNGPPKADSQSNDCHPFRTNP
What is the function of this protein?
Required for the maintenance and/or establishment of both the shoot and root meristems, probably by controlling the expression of the meristem genes and of genes required for auxin responses.  Involved in the development of the basal pole and in auxin-mediated root and vascular development in the embryo (By similarity).  Confers sensitivity to turnip mosaic virus (TuMV) probably by promoting viral movement and multiplication via interaction with TuMV VPg (Probable).
What are the official names of this protein?
OBERON-like protein, Potyvirus VPg-interacting protein, PVIPp.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PD_DICD3
Sequence: MAVTSTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGHIHPETRIIGVGRAEWDRDAYIKVVREALETFLKEPLDPALWTTLSNRLDFCNLDVEDTEGFKRLGTMLDQQNRTTINYFAMPPSTFGAICRGLGQAGLNKEPARVVMEKPLGTNLASSRVINNQVAEFFNECQVYRIDHYLGKETVLNLLALRFANSLFANNWDNRTIDHVQITVAEEVGIEGRWGYFDQAGQMRDMIQNHLLQILTMIAMSPPADLSTDRIRDEKVKVLRSLRRIDRSNVHEVTVRGQYTSGFVQGKKVPGYLEEEGANKTSNTETFVAIRVDIDDWRWSGVPFYLRTGKRLPSKCSEVVVYFKNPALNLFHDSYQQLPQNKLIIRLQPDEGVEIQILNKIPGLDHKHRLQTTKLDLSFSETFNQQHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVDSIMDAWAMDNDSPKPYQAGTWGPVASVAMITRDGRSWNEVE
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: TOLB_PECCP
Sequence: MKHVLKVAVSFLMLWAAVLHAEVRIEITQGVDSARPIGVVPFKWAGPGAAPEDVGGIVGADLRNSGKFNPIDANRMPQQPATASEVTPAAWTALGIDAVVVGQVQPSADGSYLVSYQLVDTSGNPGNVLAQNQFKVTKQWLRYAAHTASDEVFEKLSGIKGAFRTRIAYVVQTNGGQFPYELRVADYDGYNQFVVHRSPQPLMSPAWSADGSKLAYVTFESGRSALVIQTLANGAIRQVASFPRHNGAPSFSPDGSKLAFALSKSGSLNLYVMNLASGQISQVTDGRSNNTEPTWFPDSQTLAYTSDQAGRPQVYKVNANGGAPQRLTWEGAQNQDADVSADGKFLVTVGSNGGAQHISKLDLVTGAVQVLTDTFLDETPSIAPNGTMVIYSSKQGLGSVLQLVSTDGRFKARLPATDGQVKFPAWSPYL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.  TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSA_AERPE
Sequence: MAFPMPPHQTAYDRAATIFSPEGDLYQVRYAFEAVKKGWTSLGIKTNEGVVIAAEKRFIGPLVDIDDIDKIYKIDDHIGVAFAGMGGDGRILIDYARVFTVRHRLLYGEPPPVELVAKVVADVKQAYTQHGGVRPFGVALIFAGVNPDGTTKVYRTDPGGQYFSFKAIAIGSGEQVANEMFEKHYRSDMSLEEATKLALKILYAIIRKTVEDKEKAIATLPDQVELAYITVKERMFTKMTKEQVKEIVDSMREELLQL
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSL45_DICDI
Sequence: MTLFSSISSISNPMTSSKSSIASFGSGTSMSSNSIACGGGCGGGSGGILGLGLGLGLNLFGGSGSRGACGGNGRSGNPAQGGNGGSCCGGPCCGI
What are the official names of this protein?
HssA/B-like protein 45.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: TYY2_RAT
Sequence: MASDTEKLMCLTTENAEIPADFVELQPLDEIETVSLETNVSQTIEVYGDVGVDWAHGGHYHSPLIALQPLAGSNLSNGDHDQEMIIVQTREEVVDYQDSDNLLLGTEFESQMVLPVNEDDYLQPTTATFSGFMAAENGQDELSPYGGNLCGLTTIIEAGAEEGVNPDLGDKQWEQKQIQIDGLDGEFPFAMWEDNNLKEDPVAEEEAGESTPDYSEYMTGKKFPPEGIPGIDLSDPKQLAEFTSMKPKKPKGDFPRPVACSHKGCGKMFKDNSAMRKHLHIHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPYQCTFEGCGRRFSLDFNLRTHVRIHTGDKPFVCPFDACNKKFAQSTNLKSHILTHVKNKNDQ
What is the function of this protein?
Functions as a multifunctional transcription factor that may exhibit positive and negative control on a large number of genes.  May antagonize YY1 and function in development and differentiation (By similarity).
What are the official names of this protein?
Transcription factor YY2, Yin and yang 2, YY-2.
What is the protein family that this protein belongs to?
Belongs to the YY transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_ACICJ
Sequence: MKLNELRDNPGARPKSKRLGRGIGSGKGKTSGKGVKGQKAREGVSLNGFEGGQLPIYRRLPKRGFNNVNRKDYAPLNVGTLAALIESGKIDAGQKITEATLRAAGVYAGSKLAGVRLLGRGEISQKVEIEVSGASASAIAAIEQAGGSVTTTVARAEPASA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: MNTP_DESRM
Sequence: MSLFTLFALAVALGTDAFSLCIGIGIAGVNRRQIALISLTVLIFHILMPLLGWYAGGFLGSKMGQAASIAGALLLLYLGGKMIWDTIKPGKDEGPRFVITNTGGLLLLSASVSMDALSVGFTLGTQQVSLVLAAGVIGLVAGMMTFAGLTLGKYVGDWIGERAELVGGIILVGIGVKLFF
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YJDF_BACSU
Sequence: MSVTFPSSGCPSFFNIFYEEGIVMKLTIYYDGQFWVGVVEVVDNGKLRAFRHLFGKEPRDSEVLEFVHNQLLNMMAQAEQEGVRLQGRRQKKINPKRLQRQVSKELKNAGVTSKAQEAIKLELEARKQKKKQIMKEQREHVKEQRYMLKKQKAKKKHRGK
What are the official names of this protein?
Uncharacterized protein YjdF.
Protein: CIB3_HUMAN
Sequence: MGNKQTVFTHEQLEAYQDCTFFTRKEIMRLFYRYQDLAPQLVPLDYTTCPDVKVPYELIGSMPELKDNPFRQRIAQVFSEDGDGHMTLDNFLDMFSVMSEMAPRDLKAYYAFKIYDFNNDDYICAWDLEQTVTKLTRGGLSAEEVSLVCEKVLDEADGDHDGRLSLEDFQNMILRAPDFLSTFHIRI
What is the function of this protein?
Acts a an auxiliary subunit of the sensory mechanoelectrical transduction (MET) channel in hair cells (By similarity).  Plays a role in regulating hair cell MET channel localization and function (By similarity).
What are the official names of this protein?
Calcium and integrin-binding family member 3, Kinase-interacting protein 3, KIP 3.
Protein: HNRPC_XENLA
Sequence: MMASNVTNKTDPRSMNSRVFIGNLNTLVVKKTDVEAIFSKYGKIVGCSVHKGFAFVQFSNERTARTAVAGEDGRMIAGQVLDINLAAEPKANRSKTGVKRSAADMYGSSFDLEYDFPRDYYDSYSATRVPAPPPLARAVVPSKRQRVSGNASRRGKSGFNSKSGQRGGSSKSSRLKGDDLQAIKKELSQIKQRVDSLLENLERIERDQSKQDTKLDDDQSSVSLKKEETGVKLIEETGDSAEEGDLLDDDEQGEDTLEEIKDGDKETEEGEDEGDSANEEDS
What is the function of this protein?
Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles.  Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.  Single HNRNPC tetramers bind 230-240 nucleotides.  Trimers of HNRNPC tetramers bind 700 nucleotides.  May play a role in the early steps of spliceosome assembly and pre-mRNA splicing.  N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein C, hnRNP C, hnRNP core protein C.
What is the protein family that this protein belongs to?
Belongs to the RRM HNRPC family. RALY subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: AX22D_VIGRR
Sequence: MENSLGSYEKELNLKATELRLGLPGSDEPEKRATARSNKRSSPEASDEESISNGSDVTKEDNVVPPAKAQVVGWPPIRSYRKNNVQQKKEEESEGNGMYVKVSMAGAPYLRKIDLKVYKSYPELLKALENMFKCIFGEYSEREGYNGSEYAPTYEDKDGDWMLVGDVPWNMFVSSCKRLRIMKGSEAKGLGCF
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.  Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE).  Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression (By similarity).
What are the official names of this protein?
Auxin-induced protein 22D, Indole-3-acetic acid-induced protein ARG13.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LFNG_XENLA
Sequence: MLKNWGKKLLLSIVGATLTCLLVLVVDQQSRHMLETQSDHEPGSAAAVHLRADLDPANPGDGGDPANSAQDSGTFSAYFNKLTRVRRDVEQVAAPSKDSAAPEEDITANDVFIAVKTTKKFHRSRMDLLMDTWISRNKEQTFIFTDGEDEELQKKTGNVISTNCSAAHSRQALSCKMAVEYDKFIESDKKWFCHVDDDNYVNVRTLVKLLSRYSHTNDIYIGKPSLDRPIQATERISESNMRPVNFWFATGGAGFCISRGLALKMSPWASGGHFMNTAEKIRLPDDCTIGYIIESVLGVKLIRSNLFHSHLENLHQVPQSEIHNQVTLSYGMFENKRNAILMKGAFSVEEDPSRFRSVHCLLYPDTPWCPWKAAY
What is the function of this protein?
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules.  Essential mediator of somite segmentation and patterning (By similarity).  May be involved in mesoderm development (PubMed:8662522).
What are the official names of this protein?
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CCS1_PROMP
Sequence: MVIFKKFILKISSLRFAILLIIFIAISSGVGTFIPQGNDQQEYIDFYNETPILGFINGSQVIRLQLDHIYTSNWFLFSLILLCISLAACSFRRQIPSLKAALKWTDYKDEKKFYKLELITNYEIIQDADHILKADSLLRKKGWNISKFENRLSARKGLEGKLGPIIVHIGLIILLIGSAYGNFSSQSKEQYLRLGESLDLINESTNSRVKIKLKNFFIERESDGKPKQFISNLEFFSKQQNLNEIKTTQVNQPIRFKGLTIYQADWSVSNIVMEIDSVLYQLQLKPIPEIGDQIWGLLIELGRENKKNYLLTIDNENGPLKVSNIEDFSENFVYLNNNPIEINSSKLSLKKIIPSSGLIIKNDPSIPFIYLSFTLIIVGTILSLIPTNQIWILFNENTNKLFIGGLSNRNLLGFKKEFLKLSDEIKNN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: BIOH_PHOPR
Sequence: MTTALCWQTEGQGSDLVLIHGWGMNGAVWQQLLPLLTPFYRVHWVDMPGYGHSHDISADSIEEMAQLLLDKSPISATWLGWSLGGLVATQAALLAPERVTRLVTVASSPRFAAEGTWRGIQPQVLDDFRRQLGDDFQLTVERFLALQAMGSPTARQDIKLLKQAVLSRPQPNPEALSIGLRLLADVDLRAQLGDITQPWLRLYGRLDGLVPAKVAKDMDQLAPQSCRQIFAAASHAPFISHPEEFVQTLKDFIK
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OOXB_RHIME
Sequence: MSDRCELLVIGGGLIGSAIAWGAARKGARVTLLDEGDIAYRASRANFGLVWLQGKGLGHPDYMHWSIRAGQLWPELSTILLKETGIDIGWRGGGGLHFCLSESEMAARRALIARSSAEGAAIRIQLLDRDALHEIVPDIGPEVRGASLSDLDGEANPLLTLNALQLAFQQNGGRLVVQFAARNIRSEPARGFVVSDANGDEISGRRVVLAAGLGNNELARQVGLKLGLTPERGQIVVTDRIAPFLRYPSNAIRQTREGTVLLGSSHEDAGFSTGTDVETIARLCRIGTRVFPALRAARLIRAWGALRIMSPDGLPIYEEAPEMPGAYVVTCHSGVTLASLHALELGPALAEGHLGPAPRSMRSTRFAL
What is the function of this protein?
Oxidative cleavage of octopine into L-arginine and pyruvate.
What are the official names of this protein?
Opine oxidase subunit B, Octopine oxidase subunit B.
Protein: LPXK_BRUMB
Sequence: MASEAPPFWWDEPDWRALALAPAAWIYGRVSGRRLIRAVPPRVSLPVLCVGNFTVGGAGKTPTAIAFARGAIARGMKPGIVSRGYGGNYSGLHLVDPGHDGARHVGDEPLLLARHAAVALSPDRVKAAEYLKSLGCDFIIMDDGFQSARLHADFSLLVVDASRGIGNGRVIPAGPLRAPLTDQMRKTDALLCIGKGNGADFVIRQAARAGRPIYHAQLRPSSSATVAGRRWLAFAGIGNPDKFYESVRQAGGEVVETHSFADHYSFEPDDIRGLVDMARRQGLGLITTAKDHVRLATMPGVPPEFLSKLAVLDVDLEFDRTDALGHILDTVVERFKSRLHG
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RIMP_CHLP8
Sequence: MDEMIRRAIDESIAEVAVATGSDIYLVEADVRGGGRIIELTIEADKGVSIDQCAKLSRTIRARLEACEENLMLAAGDFELMVSSPGIGEPIRVSRQYLRHLGRKMKVVYLDSEGERKEIEGKLTEASLEGEEPSITIEPVVKGKKKKTSGREPLTLRLADVVKAVVQTEW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_ALIF1
Sequence: MALLEVLTFPDDRLRTVAKPVEAVTPEIQKFVDDMIETMYDEEGIGLAATQVDFHQRIVVIDVSETRDEPMVLINPVITQKSGDDGIEEGCLSVPGAKGLVPRSAEVSVSALDRDGNEFSFDADDLLAICVQHELDHLDGKLFVDYLSPLKRKRIKEKLEKIKKFNAKNQ
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: PAO1_ORYSJ
Sequence: MVAKKPRVVVVGAGISGLAAAHRLCGAGGDRFEVAVVEAGDRVGGRILTSEFAGHRVEMGATWVQGVVGSPVYALARDAGALGEEEGRGLPYERMDGFPDRVLTVAEGGEVVDADTVAGPIEELYRGMMEAARAGEAGGGGGVEEYLRRGLRAYQAARSAGGGGGGGKELEEVDEALLAMHINRERTDTSADDLGDLDLTAEGEYRDFPGEHVTIPGGYSRVVERLAAALPPGTVRLGLRLRRLKWGGTPVRLHFADGAPPLTADHVILTVSLGVLKASLGNKDTAGVGAAAIAFDPPLPPFKREAVARLGFGVVNKLFMEVEAVAPSEPEDVAGVQPAAAGFPFLHMAFRGHVSKIPWWMRGTESICPVHAGSTVALAWFAGREAAHLESLPDDDVIRGAHATLDSFLPAAPRWRVRRIKRSGWATDPLFLGSYSYVAVGSSGDDLDRMAEPLPRGPDAAADERPPSPRLLFAGEATHRTHYSTTHAAYLSGVREANRLLQHYRGGANHTT
What is the function of this protein?
Flavoenzyme involved in polyamine back-conversion (PubMed:24105034).  Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives (PubMed:24105034).  Substrate preference is thermospermine > spermine > norspermine > N(1)-acetylspermine (PubMed:24105034).  No activity detected when putrescine or spermidine are used as substrates (PubMed:24105034).  Plays an important role in the regulation of polyamine intracellular concentration (Probable).
What are the official names of this protein?
Polyamine oxidase 1, OsPAO1, OsAO4.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UFOG4_MANES
Sequence: CNKLKLDKAERGDKASVDNTELLKWLDLWEPGSVIYACLGSISGLTSWQLAELGLGLESTNQPFIWVIREGEKSEGLEKWILEEGYEERKRKREDFWIRGWSPQVLILSHPAIGAFFTHCGWNSTLEGISAGVPIVACPLFAEQFYNEKLVVEVLGIGVSVGVEAAVTWGLEDKCGAVMKKEQVKKAIEIVMDKGKEGEERRRRAREIGEMAKRTIEEGGSSYLDMEMLIQYVSERSPSRA
What is the function of this protein?
In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.
What are the official names of this protein?
Anthocyanidin 3-O-glucosyltransferase 4, Flavonol 3-O-glucosyltransferase 4, UDP-glucose flavonoid 3-O-glucosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: ATPG_BACAC
Sequence: MASLRDIKAKINSTKKTSQITKAMEMVSASKLNRAEQNAKSFVPYMEKIQEVVASIAQGSKGINHPMLNARPVKRTGYIVITSDRGLAGGYNSNVLRTVSNVIRERHNMDSNQYSIIVLGRLGRDYLKRRGFNIIDEVVGLSDHPSFTDIKDLASRAIAMFADGAYDELYIYYNHYVSKISQEVTENKILPLTDVASDKPTTAYEFEPSEEEILKVLLPQYAESLVYGALLDGKASEHAARMTAMKSATDNAMEVIDSLTLSFNRARQAAITQEITEIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SNX19_HUMAN
Sequence: MKTETVPPFQETPAGSSCHLNNLLSSRKLMAVGVLLGWLLVIHLLVNVWLLCLLSALLVVLGGWLGSSLAGVASGRLHLERFIPLATCPPCPEAERQLEREINRTIQMIIRDFVLSWYRSVSQEPAFEEEMEAAMKGLVQELRRRMSVMDSHAVAQSVLTLCGCHLQSYIQAKEATAGKNGPVEPSHLWEAYCRATAPHPAVHSPSAEVTYTRGVVNLLLQGLVPKPHLETRTGRHVVVELITCNVILPLISRLSDPDWIHLVLVGIFSKARDPAPCPASAPEQPSVPTSLPLIAEVEQLPEGRASPVAAPVFLSYSEPEGSAGPSPEVEEGHEAVEGDLGGMCEERKVGNNSSHFLQPNVRGPLFLCEDSELESPLSELGKETIMLMTPGSFLSDRIQDALCALESSQALEPKDGEASEGAEAEEGPGTETETGLPVSTLNSCPEIHIDTADKEIEQGDVTASVTALLEGPEKTCPSRPSCLEKDLTNDVSSLDPTLPPVLLSSSPPGPLSSATFSFEPLSSPDGPVIIQNLRITGTITAREHSGTGFHPYTLYTVKYETALDGENSSGLQQLAYHTVNRRYREFLNLQTRLEEKPDLRKFIKNVKGPKKLFPDLPLGNMDSDRVEARKSLLESFLKQLCAIPEIANSEEVQEFLALNTDARIAFVKKPFMVSRIDKMVVSAIVDTLKTAFPRSEPQSPTEELSEAETESKPQTEGKKASKSRLRFSSSKISPALSVTEAQDKILYCLQEGNVESETLSMSAMESFIEKQTKLLEMQPTKAPEKDPEQPPKGRVDSCVSDAAVPAQDPSNSDPGTETELADTALDLLLLLLTEQWKWLCTENMQKFLRLIFGTLVQRWLEVQVANLTSPQRWVQYLLLLQESIWPGGVLPKFPRPVRTQEQKLAAEKQALQSLMGVLPDLVVEILGVNKCRLSWGLVLESLQQPLINRHLIYCLGDIILEFLDLSASVEESAATTSASDTPGNSKRMGVSS
What is the function of this protein?
Plays a role in intracellular vesicle trafficking and exocytosis (PubMed:24843546).  May play a role in maintaining insulin-containing dense core vesicles in pancreatic beta-cells and in preventing their degradation.  May play a role in insulin secretion (PubMed:24843546).  Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) (By similarity).
What are the official names of this protein?
Sorting nexin-19.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDUS1_DROME
Sequence: MIRAPLVKALGALGSPTHQMASRAVRTSAMVAQTPAKAPEKIEVFVDDIPVQVVPGTTVLQAAAQIGVEIPRFCYHERLAVAGNCRMCLVEVEKSPKPVAACAMPVMKGWRIKTNSDLTRKAREGVMEFLLMNHPLDCPICDQGGECDLQDQAMAFGSDRSRFTDINYTGKRAVEDKDIGPLVKTIMTRCIHCTRCVRFASEIAGVDDLGTTGRGNDMQIGTYVEKLFLTELSGNVIDLCPVGALTNKPYSFVARPWEIRKVSSIDVLDAVGSNIVVSTRTNEVLRILPRENEDVNEEWLADKSRFACDGLKRQRLVAPMVRMPNGELQAVEWEGALIAVAKAIKAAGGQIAGISGQLADLEAQVALKDLLNRLGSEVVATEQGFIAGGTDNRANYLLNSTIAGLEEADAVLLVGTNPRYEAPLVNTRLRKAYVHNELQIASIGPKIDLSYDHENLGADAALVKDVCSGAHAFSKVLEGAKKPAIIIGADLLERADGAAIHATVAEYCKKLKKPNWNPFNVLQTNAAQVGALDVGYKAGAQTAVKAQPKVLFLLNADAGKVTREQLPKDCFVVYIGSHGDNGASIADAVLPGAAYTEKQGIYVNTEGRPQQTLPGVSPPGMAREDWKILRALSEVVGKPLPYDNLDELRNRLEDVAPHLTRLGQLEPAGDAGAAGTISKSIGGGAIDIKLKELRDYFMTDAISRASPTMAKCISAVNKQQRENEAKQSVAI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).  This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme.  It may form part of the active site crevice where NADH is oxidized (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, Complex I-75kD, CI-75kD.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Note=Matrix and cytoplasmic side of the mitochondrial inner membrane.
Protein: NU2M_MUSKA
Sequence: MKPPILIIIMFTVISGTIMVLMSSHWLMIWIGFEMNMLAIIPILMKKYNPRAVEAATKYFLTQATASMLLMLGIIMNLLLTGQWAVLSTLNPIVSNTMTVALAMKLGLSPFHFWVPEVTQGIPLLSGMVLLTWQKIAPLSILYQMAPSMNPHLLMTMALMSVLVGGWGGLNQTQLRKILAYSSIAHMGWMIAVMTYSPTLMLLNLSIYITMTLGTFMLFMFNSSTTTLSLSLTWNKLPLITSLILIIMLSLGGLPPLSGFIPKWMIIHELTKNNMIITTMLMTITALLNLYFYMRLTYATALTMFPSTNNMKMKWQFESTKNMTMLPPLIVISTMLLPLTPMMSTLF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NHAP2_ECODH
Sequence: MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIAMIQHHESNISWMFIVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFSLTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLKIGVRVAEEEAES
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_LARHH
Sequence: MKNSLYQRHIISISDLNREELEMVVKVAGDLKRTPRHELLKNKVVASCFFEASTRTRLSFETAVQRLGGTVIGFSDGGNTSLAKKGETLADSVQIITSYVDAYVMRHPQEGAARLASMFSNGKPVINGGDGSNQHPTQTLLDLFSIYETQGRLDGLKVAFVGDLKYGRTVHSLAQALSLFGCRFYFIAPEALAMPEYICEELDDKGIEYSLHTSIEEVVGELDILYMTRVQKERFDETEFKHMKSKFVLNVDTLKGAQDNLRILHPLPRVDEIAIEVDHTPYAYYFQQAENGVYAREALLALVLNETI
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.