PharMolix/UniProtQA huggingface dataset:
Protein: TTCA_BARHE
Sequence: MEENLERTESLAREADDCHPIFRIAPSTVEFNKLRKRLLRHIRQAFDDFSMLSSGKKWLVALSGGKDSYGLLALLLDLKWRGLLPVEILACNLDQGQPGFPKHILPDFLNSYQIPHRIEYQDTYSIVTDKLVHTQTYCSLCSRLRRGNLYRIAREEGCSALVLGHHRDDVLETFFMNLFHGGRLAAMPGKLINDEGDLFVLRPLVYAAEEDMEKFSQAMQFPIIPCNLCGSQDGLQRNAMKEMLKDIERKMPGRKDTMIRALTNVRPSHLLDKKFFDFKNLF
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_ALKEH
Sequence: MSKSKFERKKPHVNVGTIGHVDHGKTTLTAAMTVVLAEAFGGDARAFDQIDNAPEEKARGITIATAHVEYETSERHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPYIVVYLNKADMVDDEELLELVEMEVRELLSDYDFPGDDTPVITGSALKALEGDDSEIGKPSIIKLAEAMDEYIPTPERPVDQPFLMPIEDVFSISGRGTVVTGRVERGVIKTGEEVEIVGLKETQKTTCTGVEMFRKMLDQGEAGDNIGALLRGTKRDEVERGQVLCKPGSITPHTKFECEVYVLSKDEGGRHTPFFNGYRPQFYFRTTDVTGSCELPEGVEMVMPGDNVKMTVSLIAPIAMEDGLRFAVREGGRTVGAGVVSKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNA_PSEAE
Sequence: MGARRWLVSGVGYRLEESLEYRTLVPEALSIWRMAGANRMLFDCFDVDSKAARRSVAILSSCLRIECWGRDVVLRALNSNGRALLAPLSEDCPAQVTCLRDGDTLHWRFPQEESHADEWRRLHGLSSLEALRRVLGTLGDAEGPVLLGGLFSFDLAEQFEPLPAPAEPARHCPDYLFLVPELLLDIDHLARRTSLQAFVHDPAGHDRLAASLRQCADEFHGAVEEASESPVAGVRAGNYQVDLDDASFARQVERLQAHVRAGDVFQIVPSRSFSMPCADPWRAYRQLCLRNPSPYRFFLDAGDFCLFGASPESALKYDAESREVELYPIAGTRPRGRDARGAIDAELDNRLEAELRLDAKEIAEHMMLVDLARNDLARVCRSGTRQVRDMLKVDRYSHVMHLVSRVAGELHGELDALHAYRACLNMGTLVGAPKVRAMQLLRQYEDGYRGSYGGAIGILDSAGNLDTSIVIRSAEVREGIARVRAGAGVVLDSDPRLEAEETRNKALAVLTAVAAAERERGERDAHHAVG
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, a precursor for Pseudomonas quinolone signal (2-heptyl-3-hydroxy-4-quinolone; PQS) production which is required to induce the genes for the biosynthesis of the virulence factor pyocyanine (PCN), a characteristic blue-green phenazine pigment produced by P. aeruginosa (PubMed:11591691, PubMed:2153661, PubMed:23449919).  In the first step, the glutamine-binding beta subunit (PhnB) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (PhnA) to produce anthranilate (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, pyocyanine specific, AS, ASI, Anthranilate synthase alpha subunit, pyocyanine specific.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: OX2G_HUMAN
Sequence: MERLVIRMPFSHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINITQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNITCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEVICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVILLVLISILLYWKRHRNQDRGELSQGVQKMT
What is the function of this protein?
Costimulates T-cell proliferation.  May regulate myeloid cell activity in a variety of tissues.
What are the official names of this protein?
OX-2 membrane glycoprotein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RK23_ACOCL
Sequence: MDGIKYAVFTEKSIRLLGNNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKGRRVGPIKGHTMHYRRMIITLQPGYSIPPLIEKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HMEN_DROME
Sequence: MALEDRCSPQSAPSPITLQMQHLHHQQQQQQQQQQQMQHLHQLQQLQQLHQQQLAAGVFHHPAMAFDAAAAAAAAAAAAAAHAHAAALQQRLSGSGSPASCSTPASSTPLTIKEEESDSVIGDMSFHNQTHTTNEEEEAEEDDDIDVDVDDTSAGGRLPPPAHQQQSTAKPSLAFSISNILSDRFGDVQKPGKSMENQASIFRPFEASRSQTATPSAFTRVDLLEFSRQQQAAAAAATAAMMLERANFLNCFNPAAYPRIHEEIVQSRLRRSAANAVIPPPMSSKMSDANPEKSALGSLCKAVSQIGQPAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGASGSGVNASSPQPQPIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSDRPSSGPRYRRPKQPKDKTNDEKRPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPLTKEEEELEMRMNGQIP
What is the function of this protein?
This protein specifies the body segmentation pattern.  It is required for the development of the central nervous system.  Transcriptional regulator that represses activated promoters.  Wg signaling operates by inactivating the SGG repression of EN autoactivation.
What are the official names of this protein?
Segmentation polarity homeobox protein engrailed.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
Protein: IDI_SALPB
Sequence: MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDGQLLVTRRSLSKKAWPGVWTNSVCGHPQQDETTEEAIIRRCRFELGVEITDLTPVYPHFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLLATPWAFSPWMVMQASDEQARERLLDYCQR
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHB_MOUSE
Sequence: MALGALLLLLGVLGTPLAPGARGSEAEGQLIKKLFSNYDSSVRPAREVGDRVGVSIGLTLAQLISLNEKDEEMSTKVYLDLEWTDYRLSWDPAEHDGIDSLRITAESVWLPDVVLLNNNDGNFDVALDINVVVSFEGSVRWQPPGLYRSSCSIQVTYFPFDWQNCTMVFSSYSYDSSEVSLKTGLDPEGEERQEVYIHEGTFIENGQWEIIHKPSRLIQLPGDQRGGKEGHHEEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDAGEKMGLSIFALLTLTVFLLLLADKVPETSLAVPIIIKYLMFTMVLVTFSVILSVVVLNLHHRSPHTHQMPFWVRQIFIHKLPPYLGLKRPKPERDQLPEPHHSLSPRSGWGRGTDEYFIRKPPSDFLFPKLNRFQPESSAPDLRRFIDGPTRAVGLPQELREVISSISYMARQLQEQEDHDALKEDWQFVAMVVDRLFLWTFIVFTSVGTLVIFLDATYHLPPPEPFP
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Acetylcholine receptor subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-1/CHRNB1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: SPA37_BOVIN
Sequence: MRTERTSFLLALGLLVSGFCSRVHCLPENVTPEEQHKGTSVDGHSLASSNTDFALSLYKQLALKDPNKNVIFSPLSISIALAFLSLGAHDHTVTEILEGLKFNLTETPETEIHQGFQHLLQTFNQPSNQLQLSVGNAMFASEELKLLDKFRKDAEAFYASEVLSTNFKDSEAAVKLINEYVKNKTHGKIEKLFNDLDVLTNLILLNYIFFKAQWKTPFNPNHTYESEFHVSQNERVIVPMMTLYLETPYFRDEELGCTLVELTYTSNDSALFILPDEGKMQDLEAKLTPETLTRWRSSLQPRLIHRLRLPRFSISSHYQLKDILSQLGIKKIFTSDAGFSGITDDHKLAVSHVIHKAVLDVGEEGTEGAAVTAVVMATSSLLHTLTVSFNRPFLLSIFCKETQSIIFWGKVTNPKEA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Serpin A3-7.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, chromaffin granule. Secreted.
Protein: RIMO_KLEP3
Sequence: MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPTYDNADMVIVNTCGFIDSAVQESLEAIGEALKENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYSPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLAEAKRLADAGVKELLVISQDTSAYGVDVKHRTGFHNGMPVKTSMVSLCEELAKLGIWVRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSADRQLARIKQWREICPDLTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGATANELADQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVLVDEVDEEGAIGRSMADAPEIDGAVYLNGETRVKPGDVVRVKVEHADEYDLWGTRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_BLEZA
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RSMF_PSET1
Sequence: MDANTFIPEHFIDDVKTYLPAHLDIDDFINACRRPLRKSIRVNTLKISVTEFKQYAKQKNWLLTPIPWCEEGFWLERPAAEEQNLALGNTDLHLSGAMYVQEASSMLPPIALKQSIEHTNYVLDMASAPGSKTSQLAALMNNQGVLVANELSSSRLKVLSATLKRMGVGNCALSHFDGVIFGNYMFECFDSILLDAPCSGEGTVRKDADALKNWSIDSNIEIAQVQKDLIKSAFYALKPGGTLVYSTCTLTPLENQHVCDFLLSEFGDCIIPESLSDLFPGASKATTPEGYLHVWPQTFDSEGFFIAKFKKQASSDNPNLKVKKGAFPFQQFESKKSAVFMQTLKQQFGLNTLPGILMQRDKELWLFPQEFEAVQNKIKYARLGIQLGAIHNNGVRLAHEFATAFGKQCKSNVLPLTDTQANDYFQGKDIRLADVSQNTGEVILTLCGCPIGLGKWQKNKVKNSLPRDLVQNTQLITWAQSN
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRC10_CHLRE
Sequence: MNSLEAGRVLSVLDEALEGIRLISYVTQDVLDTAEQLRDMLGEDLANALIKHRQLIQSAKSTLNNDQVQASTLELVRLLKKSPSAQRLQVLPYERTYGILQTLQYFEQLRQFAQKRLTTTVEEDSSNREFFEEVRDREERAVAEQEQLKQKLKLQRVELQKAAGTIQVSEDRARGEVSEVQSSTQQSRAAIEGSARAQSEADKSSFQSDLDQVTKELAAARAELARLRQEHKDNEALLRKARKRAEQDVEVQIGEYDADVGAKEEELGKARAEYEEVLRQLQEYNSGWSEMYQERLEYEERERRLADQRFQAALLAVRQNHAARVIQSYWRGFKKAREAAKKKAKKLEKAKAAKKK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes (PubMed:23427265, PubMed:25411337).
What are the official names of this protein?
Dynein regulatory complex protein 10, Flagellar associated protein 84.
What is the protein family that this protein belongs to?
Belongs to the DRC10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: VPR_SIVMK
Sequence: MEERPLENEGPQREPWDEWVVEVLEELKEEALKHFDPRLLTALGNHIYNRHGDTLEGAGELIRILQRALFMHFRGGCNHSRIGQPGGGNPLSTIPPS
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: DHSD_NEUCR
Sequence: MASVARSSALLKQVAAQQSVAANGLRVAAFHTTSRKSLLPPPPQRIEGTVNDPVEVPPPSPSHGSYHWTFDRVVAAGLIPLTVAPFAAGSLNPTMDAVLAATILIHSHTGFGNIIVDYVPSKRVPKARKVFTWGLNAATVLVGLALYEFETTDVGLTETIKRVWKA
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial, CybS, Succinate-ubiquinone reductase membrane anchor subunit.
What is the protein family that this protein belongs to?
Belongs to the CybS family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNC_ROSHA
Sequence: MDEKEIKFIQDQIGYTFKNQELLVQAFTRRSYSMENGGQDNEVLEFIGDKALDFVVVKQLSEEFGHYSKKYQNWEKWGKTEETGTFISDLDEGELTEIKKQLVQKNTLADAIDNLGIAYYLIMGKGDVEKNIQDSLSVKEDLFEAILGAIALDSNWDIEALQDSMNVMLNPGELMFDEDVNYVAEIQAWSSANSGNIPLHCFYPTSMQGTWYMPRHHMCIYGKAEQDTHFACEVLIPGIDYHFVGYGRSKNLARMDASRLAYEYLKDEDMLFSIRDEIDDPNYNDSIGQLEILARRGYFSIPQYDFKETHDEDGNPVWNCKCSIKEKDTVTNGRSSSKKDAKKQAAYDMLTFVLEEE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity).
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_CLOB6
Sequence: MGILNKIFGTYSERELRRVNPIVNKIEALDEKMQSLKDEDFKLKTEEFKSRLEKGEKLDDILPEAFALVREAAHRTIGLKHYREQLIGGVVLHQGRIGEMKTGEGKTLVATLPAYVNALTGKGVHIVTVNDYLAKRDRDLMAPVYEFLGLKVGVILHNLNNEERQEAYGSDITYGTNSEFGFDYLRDNMVVYKEERVQRKLNFSIVDEVDSILIDEARTPLIISGQGEKSTEFYKVADYFTKSLIAEKDFTIDEKANSAMLTDEGVNKAENFFKVDNYADAENMEIQHHVVQALKANYVMKKDKDYMIKDGEILIVDEFTGRAMEGRRYSDGLHQAIEAKEGVRVERESKTLATITYQNYFRMYNKLSGMTGTAQTEENEFREIYGLDVIVIPTHEPIARIDNADVVYKSEKGKFKAIVDEIVERYKKGQPMLVGTVSIEKSEMLSSMLKKKGVPHQVLNAKYHEKEAEIISHAGEYGMVTIATNMAGRGTDIKLTKEAEEAGGLMIIGTERHESRRIDNQLRGRSGRQGDPGESRFFVSLEDDLMRIFGSERIQGIVDKLGLAEDEAIESKMVSSAIESAQKKVEGNNFDIRKTLLQYDDVINKQREIIYKQRSEVLEGEDLKDQIRDMIRDVVYTAVNSHISGVEEEFETELQNLVNYLEDICLPKALVKVKDISNLSDEEIKEKLLEAVENIYSNKEKEIGEEQIREIERVILLRVVDTKWMDHIDDMDHLKQGIGLRAYRQQDPVQAYQFEGSEMFEEMIYNIKVDTVRYLFHVEVEKAPEREKVAKETSTNYDEDSVKKQPIKKENRIGRNDLCPCGSGKKYKNCCGRMA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: GUNC_FUSOX
Sequence: MKSLSLILSALAVQVAVAQTPDKAKEQHPKLETYRCTKASGCKKQTNYIVADAGIHGIRQKNGAGCGDWGQKPNATACPDEASCAKNCILSGMDSNAYKNAGITTSGNKLRLQQLINNQLVSPRVYLLEENKKKYEMLHLTGTEFSFDVEMEKLPCGMNGALYLSEMPQDGGKSTSRNSKAGAYYGAGYCDAQCYVTPFINGVGNIKGQGVCCNELDIWEANSRATHIAPHPCSKPGLYGCTGDECGSSGICDKAGCGWNHNRINVTDFYGRGKQYKVDSTRKFTVTSQFVANKQGDLIELHRHYIQDNKVIESAVVNISGPPKINFINDKYCAATGANEYMRLGGTKQMGDAMSRGMVLAMSVWWSEGDFMAWLDQGVAGPCDATEGDPKNIVKVQPNPEVTFSNIRIGEIGSTSSVKAPAYPGPHRL
What are the official names of this protein?
Endoglucanase type C, Cellulase, Endo-1,4-beta-glucanase, Endoglucanase I, EG I.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
Protein: PROA_MYCSS
Sequence: MSVHAPAAPDLRTEVHDAARRARVASRTLATLSTETKNRALRAAADRVLMDAHLIIAGNERDLEKARAAGTPDAMLDRLALNPQRIDGVAAGLRQVASLPDPVGEVLRGNTLVNGLQLRQQRVPLGVVGIVYEGRPNVTVDAFGLTLKSGNAVLLRGSSSAAHSNAALVDSLRAALVAEGLDANAVQLLPSHDRASVTHLIQARGLVDVVIPRGGAGLIDAVVRDAQVPTIETGVGNCHVYVHSAADLDMAETILLNAKTRRPSVCNAAESVLIDAAIAEEAVPRLTKALQDAGVTVHADPTEEELRAEFLSMDIALAVVDGVDAAIAHVNEYGSGHTEAIVTADLAAAQRFTERVDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIVWGDGHTRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUT_CHLT3
Sequence: MIRIHCKKLHPEARLPKYATEGAAGMDISACLDEPISVEAQSVALVPTGLALEIPPGYEAQLRPRSGLALKHLISLPNAPATIDADFRGELKVILINHGKDAFEVKHGDRIAQMVIAKVEKVAVVEVAALSETKRGEGGFGHTGVEG
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: HIS7_GEOUR
Sequence: MSRKAVIERITKETQIKLSLNIDGSGEARVCTSVPFLDHMLNLFARHGLFDLEVEAKGDIDIDFHHTVEDIGIVLGEALKQALGDKQGIRRYGQATVPMDETLASVAVDLSGRPYLVYNVRLPKVKIGEFDVELAREFFQALTNNLAANLHINVMYGDNVHHILEACFKALARALDQATQQDPRIAGVMSTKGKL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_BAUCH
Sequence: MLIIDNITILRQTIKQWRKSIQSIALIPTMGNLHDGHMTIVNQGRSHTNIVIVSIFVNPMQFDREEDLFLYPRTLQSDYEKLHKIGVDAVFVPSVETMYRDNINCHTFLDVPNLSSILEGIYRPNHFRGVATIISKLFNLVQPNVVYFGEKDFQQLVLIRQMVRDMNYDIEIIAVPTVRANDGLALSSRNSYLTPEQRKIAPKLYQVMQTLVTNLCSGEKNIDVLLNKAAKQLSKFGFTPEILEIRDAITLQPITINSKKVVVLFSAWLGKARLIDNTQVSIPKE
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_AZOPC
Sequence: MADLNINIGKLKFKNPVLAASGTFGYGIEYSDFVDLSKIGGIFTKGITLYHREGNDYPRMAETSSGMLNAVGLQNRGVTYFIKNIYPKVKNIETNIMVNISGSTIEDCVSCAEKINELDKIPAIELNISCPNMKQGGMAFGTNCSNASEIVNAVRKVYHKILIVKLSPNVTDITEIAKAVEIAGADAVSLINTLIGMAIDIKIKKPILSTVTGGLSGPCIKPIALRMVYQTYKIVKIPIIGLGGISNSDDAIEFILAGASAIQVGTYNFIDPTISTKIVDGINAYLDKYHLLSIKELVGELL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOLA_HAEIN
Sequence: MQNNRQKKGINAFAISILLHFILFGLLILSSLYHTVEIMGGGEGEGDVIGAVIVDTGTAAQEWGRIQQQKKGQADKQKRPEPVVEEKPPEPNQEEIKHQQEVQRQEELKRQQEQQRQQEIKKQQEQARQEALEKQKQAEEAKAKQAAEAAKLKADAEAKRLAAAAKQAEEEAKAKAAEIAAQKAKQEAEAKAKLEAEAKAKAVAEAKAKAEAEAKAKAAAEAKAKADAEAKAATEAKRKADQASLDDFLNGGDIGGGSASKGGNTNKGGTQGSGAALGSGDGGKVGDQYAGVIKKEIQRRFLKDPNFAGKVCRIKIQLGRDGTILGYQKISGSDDICSAALSAVARTKKVPAAPSDEIYEKYKSPIIDFDIR
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolA.
What is the protein family that this protein belongs to?
Belongs to the TolA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HSLO_THEMA
Sequence: MIYYGTMFDHKVRFSIVRMREVVEEARNRHALSYLATVVLGRALIGAALVTPWLAEKERWTLDIEGNGPIRRVVAQSTSEFTVRGYVANPKVELPLNEKGKFDVAGAIGQGVLRVVRDLGLKTPFVSQVPLVSGEIAEDLAYYFAVSEQIPSAFSIGVLVDSDGVKIAGGFAVQIIDRTLEQEKVEMIEKNIKNLPSISKLFQEAEPLDVLERIFGEKVGFVETAEIKYKCDCNREKAKNALLVLDKKELEDMRKEGKGEVVCKWCNTRYVFSEEELEELLKFKVDDSGS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_GEOMG
Sequence: MSQNFGRISQVIGAVIDVEFEPGKLPPIYNALRVTNPAIDDKEYNLVLEVAQHLGENSVRTIAMDSTDGLVRGQAALDTGKQISVPVGRKTLGRILNVIGEPVDEMGPVNAEKEYGIHRESPSFVDQSTKVEAFTTGIKVVDLLAPYARGGKIGLFGGAGVGKTVLIMELINNIAKQHGGFSVFAGVGERTREGNDLWMEMKESGVLDKAALVYGQMNEPPGARARVALSALSIAEYFRDEEGQNVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGELQERITSTTKGSITSVQAIYVPADDLTDPAPATAFAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPQVIGEEHYAIARQVQYVLQKYKDLQDIIAILGMDELSEEDKLVVARARKIQRFLSQPFHVAEAFTGSPGKYVELKDTIKGFQEIVAGKHDDIPEQAFYMVGTIEEALEKAKKLAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.