PharMolix/UniProtQA huggingface dataset:
Protein: ENO_BORBR
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGAMGRASVPSGASTGSREAIELRDGDKGRYLGKGVLRAVENLNTEISEALMGLDAQEQTFVDRTLIELDGTDSKERLGANAMLAASMAVARAAADESGLSLYRYFGGSGPMSMPVPMMNVINGGAHANNTLDLQELMILPVGAASFREALRWGAEVFHMLKKLIHDQGMSTAVGDEGGFAPNVASHEAAIQLILKAITEAGYEPGTQIALGLDCASSEFYRDGKYTLAGEGGVSLSSQEFANLLATWCDKYPIISIEDGMAENDWDGWKLLTDQLGKKVQLVGDDLFVTNTRILREGIQKGVANSILIKINQIGTLTETFAAIEMAKRAGYTAVVSHRSGETEDSTIADIAVATNAMQIKTGSLSRSDRMAKYNQLLRIEEELAEVASYPGLEAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: H39_STYLE
Sequence: NTGGKAPRKHIAHKQAKKSSAAAATGGVKKPHRFRPGTVALREIRRFQKSTELLIRKLPFQRLVREIASEFKNDLRFQSSAVLALQEASEAYLVGLFEDTNLAAIHAKRVTIMP
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3-2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS21_DICTD
Sequence: MTEVRVGKDESLDSALKRFKKKLQEDGVLADIRRHEYYEKPSEKRNRKKAQSKKKK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL35_ALIFM
Sequence: MPKMKSNKGASKRFKKTAGGIKFKHATKRHILTKRTTKNKRQLRPNSLLPKCEVAAVARMLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: OSTP_CHICK
Sequence: MKLAFLCLCFISIAAAWPVSKSRQHAISASSEEKYDPRSHHTHRYHQDHVDSQSQEHLQQTQNDLASLQQTHYSSEENADVPEQPDFPDIPSKSQEAVDDDDDDDNDSNDTDESDEVVTDFPTEAPVTPFNRGDNAGRGDSVAYGFRAKAHVVKASKLRKAARKLIEDDATAEVGDSQLAGLWLPKESREQDSRELAQHQSVENDSRPRFDSPEVGGGDSKASAGVDSRESLASRSAVDTSNQTLESAEDAEDRHSIENNEVTR
What is the function of this protein?
Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
What are the official names of this protein?
Osteopontin, Bone sialoprotein 1, Secreted phosphoprotein 1, SPP-1.
What is the protein family that this protein belongs to?
Belongs to the osteopontin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CD244_MOUSE
Sequence: MLGQAVLFTTFLLLRAHQGQDCPDSSEEVVGVSGKPVQLRPSNIQTKDVSVQWKKTEQGSHRKIEILNWYNDGPSWSNVSFSDIYGFDYGDFALSIKSAKLQDSGHYLLEITNTGGKVCNKNFQLLILDHVETPNLKAQWKPWTNGTCQLFLSCLVTKDDNVSYALYRGSTLISNQRNSTHWENQIDASSLHTYTCNVSNRASWANHTLNFTHGCQSVPSNFRFLPFGVIIVILVTLFLGAIICFCVWTKKRKQLQFSPKEPLTIYEYVKDSRASRDQQGCSRASGSPSAVQEDGRGQRELDRRVSEVLEQLPQQTFPGDRGTMYSMIQCKPSDSTSQEKCTVYSVVQPSRKSGSKKRNQNSSLSCTVYEEVGNPWLKAHNPARLSRRELENFDVYS
What is the function of this protein?
Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48.  SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.  Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2.  Acts as activating natural killer (NK) cell receptor (PubMed:8326140, PubMed:12734329, PubMed:19648922, PubMed:20962259).  Activating function implicates association with SH2D1A and FYN.  Downstreaming signaling involves predominantly VAV1, and, to a lesser degree, INPP5D/SHIP1 and CBL.  Signal attenuation in the absence of SH2D1A is proposed to be dependent on INPP5D and to a lesser extent PTPN6/SHP-1 and PTPN11/SHP-2.  Stimulates NK cell cytotoxicity, production of IFN-gamma and granule exocytosis (PubMed:8326140, PubMed:15169881, PubMed:15998796, PubMed:22683124).  Optimal expansion and activation of NK cells seems to be dependent on the engagement of CD244 with CD48 expressed on neighboring NK cells (PubMed:15905190).  Regulation of NK cell activity by adapters Sh2d1b and Sh2d1b2 is reported conflictingly (PubMed:16127454, PubMed:16425036).  Acts as costimulator in NK activation by enhancing signals by other NK receptors such as NCR3 and NCR1.  At early stages of NK cell differentiation may function as an inhibitory receptor possibly ensuring the self-tolerance of developing NK cells (By similarity).  Involved in the regulation of CD8(+) T-cell proliferation; expression on activated T-cells and binding to CD488 provides costimulatory-like function for neighboring T-cells (PubMed:11739483).  Inhibits inflammatory responses in dendritic cells (DCs) (PubMed:25643613).
What are the official names of this protein?
Natural killer cell receptor 2B4, NK cell type I receptor protein 2B4, NKR2B4, Non-MHC restricted killing associated, SLAM family member 4, SLAMF4, Signaling lymphocytic activation molecule 4.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell membrane. Note=Receptor engagement results in a recruitment to lipid drafts essential for the subsequent tyrosine phosphorylation of the ITSMs.
Protein: PAB4L_HUMAN
Sequence: MNVAAKYRMASLYVGDLHADVTEDLLFRKFSTVGPVLSIRICRDQVTRRSLGYAYVNFLQLADAQKALDTMNFDIIKGKSIRLMWSQRDAYLRRSGIGNVFIKNLDKSIDNKTLYEHFSAFGKILSSKVMSDDQGSKGYAFVHFQNQSAADRAIEEMNGKLLKGCKVFVGRFKNRKDREAELRSKASEFTNVYIKNFGGDMDDERLKDVFSKYGKTLSVKVMTDSSGKSKGFGFVSFDSHEAAKKAVEEMNGRDINGQLIFVGRAQKKVERQAELKQMFEQLKRERIRGCQGVKLYIKNLDDTIDDEKLRNEFSSFGSISRVKVMQEEGQSKGFGLICFSSPEDATKAMTEMNGRILGSKPLSIALAQRH
What is the function of this protein?
May bind RNA.
What are the official names of this protein?
Polyadenylate-binding protein 4-like, PABP-4-like, Poly(A)-binding protein 4-like.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
Protein: LAC2_FOMPI
Sequence: MLLSSAFVGSCLAILNFAAAVSAQGGLSRTTLNIVNKVISPDGYSRDSVLANGIHPGPLISGNKGDTFQINVNNQLHDNSMNTSTTVHWHGIDQHHTNWADGPAFVTQCPIVPEHSFLYNFTVPDQAGTFWYHSHESVQYCDGLRGPLVVYDPEDPHKDLYDVDDDTTIISLSDWYHSPAHELLPGPIPPNSTLINSLGRPDGSDLPVTIIEVDPTKRYRFRLISMACHPYFDFSIDGHNMTIIEADGSNTEPLSDIDQIRIYPAQRYSFVLEPNQTPGDYWIRAAPLQLGNTSNPDTTTSLGLAILRYTNRSGYAQAASVDPYDISQTPIPVNPLLEQNLHAYGDVPELDEECDDCKLTFDFAFNFTAVDFTVNGTSYVNPTVPVLLQILNGTYTAQELLPHHSVYTLPRNKTIEITMPGAVTGGPHPMHLHGHSFYVIQSMGSDTTNTVNPVLRDTVAVGGATGDNVVIRFRTDNPGPWIMHCHIDFHLALGFAVVLAEAPQDVAEYVSPIPTWDELCPIWDNAPSHN
What is the function of this protein?
In vitro, has activity towards 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS), 2,6-dimethoxy-phenol, and guaiacol (PubMed:34116754).  Although brown rot fungi preferentially degrade hemicellulose and cellulose, the enzyme may contribute to generating small amounts of lignin breakdown products required for catalytic reactions (PubMed:34116754).
What are the official names of this protein?
Laccase-2, FpLCC2.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TBA1_GOSHI
Sequence: MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPSDKTVGGGDDAFYTFFSETGAGKHVPRAIFVDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFSAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVSVLLDNEAIYDICRRSLDIERPTYTNLNRLVSQVISSLTASLRFDGALNVDVTEFRTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVAEITNSAFEPSSMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFADWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNSTSVAEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGADSAEGDEEDEGDEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1 chain, Alpha-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RSP5_ASPCL
Sequence: MGSNLPSQPNLRLTIIAADGLYKRDVFRFPDPFAVATVGGEQTQTTSVIKKTLNPYWNEMFDLRVNEESILAIQIFDQKKFKKKDQGFLGVINVRIGDVIDLEMGGDEMLTRDLKKSNDNLVVHGKLIINLSTNLSTPNTNQANGLHRSHIQPSTSSGLVPQVGASAAHPAASPAPIDPAASNPSLHPQRVPSTNRPPSTVAPGAAAGATPTNTQGSRTNLSSFEDSQGRLPAGWERREDNLGRTYYVDHNTRTTTWTRPSSNYNEQTQRTQREANMQLERRAHQSRMLPEDRTGANSPNLPETSQQAPTPPAGGSANAVSMMATGATTAGTGELPPGWEQRTTPEGRPYFVDHNTRTTTWVDPRRQQYIRMYGQNANGTNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQGVPQYKRDFRRKLIYFRSQPALRIMSGQCHVKVRRNNIFEDSYAEIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGVLELTFAVDDEKFGERRTIDLKPGGRDIPVTNENKGEYVELVTEWKIVKRVEEQFNAFMSGFNELIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQESDDVIQNFWKVVRTWDAEQKSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKSGDPVALPKSHTCFNRLDLPPYKTYETLEHKMSIAVEETLGFGQE
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Probably involved in the regulatory network controlling carbon source utilization.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase hulA, HECT ubiquitin ligase A, HECT-type E3 ubiquitin transferase hulA.
What is the protein family that this protein belongs to?
Belongs to the RSP5/NEDD4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_ECO45
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: RL4_HELHP
Sequence: MSKAILLDKKLQQSNELALPERYAQIKEHNLYLYVKSYLSSLRANSASAKKRGEVSGGGKKPWKQKGGGRARAGSITSPVFVGGGVSHGPSNDKNYTLKINKKQKRLALECALFQKAQEGKLFVVDSLAMPSGKTKDAYAMFKALKQRSTLFVAQMSDEPTFLAFRNLQQCYLADANELNAYLVAAFRSVVIEKAVFDEIIAEKKGE
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PTLA_STRAW
Sequence: MPQDVDFHIPFPSRRSPDFERARADHLSWPRALGLIGTDAAAERHSRGGYADLAARFYPSATGADLDLGVDLMSWFFLFDDLFDGPRGEDPQETRKLTDAVAAALDGPLPTSAPPIAHGFADVWRRTCQGMSPAWRARSARHWRNYFSGYVDEAVSRHLNTPYDSAGHYLAMRRQTIGVQPTVDLAERSCHCEVPQRVFDSAVLFAMLQIATDTNLILNDIASLEKEEARGELNNMVFILMREHGWTRGRSIAHMQDGVRTRLEQFLLLEACLPKVYDTFELTAQERESAEKYRMDGVRSVIRGSYDWHRSSGRYAADYAIAASYQGYLEELGSTL
What is the function of this protein?
Catalyzes the cyclization of farnesyl diphosphate (FPP) to the tricyclic sesquiterpene pentalenene in the biosynthesis of neopentalenolactone antibiotic.
What are the official names of this protein?
Pentalenene synthase, PS, Pentalenolactone biosynthesis protein A, Sesquiterpene cyclase, Sesquiterpene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RL7_CORGL
Sequence: MAKLTKDELIEAFKEMTLIELSEFVKEFEEVFDVTAAAPVAVAAAGAAGGEAAAAEEKDEFDVVLEDAGAKKIGVIKAVRELVSGLGLKEAKELVEGAPKAILEGANKDDAEAAKAKLEEAGAKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GFL_ARATH
Sequence: MDGSLYGECGNYIGPEIESDRDSDDSVEDEDLQEPGGSNGWITTINENQNIVLPEDKKYYPIAKEVYGEDVETLVMDEDEQSLEQPIIKPVRDIRFEVGVIKDQTTTYVSTLFLIGLMSNPALVRNVALVGHLQHGKTVFMDMLVEQTHRMSTFNAENDKHMRYTDTRVDEQERNISIKAVPMSLVLEDSRSKSYLCNIMDTPGNVNFSDEMTASLRLADGAVFIVDAAQGVMVNTERAIRHAIQDHLPIVVVINKVDRLITELKLPPRDAYYKLRYTIEVINNHISAASTNAADLPLIDPAAGNVCFASGTAGWSFTLQSFARMYAKLHGVAMDVDKFASRLWGDVYYHPDTRVFNTSPPVGGGERAFVQFILEPLYKIYSQVIGEHKKSVETTLAELGVTLSNSAYKLNVRPLLRLACSSVFGSASGFTDMLVKHIPSPREAAARKVDHSYTGTKDSPIYESMVECDPSGPLMVNVTKLYPKSDTSVFDVFGRVYSGRLQTGQSVRVLGEGYSPEDEEDMTIKEVTKLWIYQARYRIPVSSAPPGSWVLIEGVDASIMKTATLCNASYDEDVYIFRALKFNTLPVVKTATEPLNPSELPKMVEGLRKISKSYPLAITKVEESGEHTILGTGELYLDSIIKDLRELYSEVQVKVADPVVSFCETVVESSSMKCFAETPNKKNKLTMIAEPLDRGLAEDIENGVVSIDWNRVQLGDFFRTKYDWDLLAARSIWAFGPDKQGTNILLDDTLPTEVDRNLMMGVKDSIVQGFQWGAREGPLCDEPIRNVKFKIVDARIAPEPLHRGSGQMIPTARRVAYSAFLMATPRLMEPVYYVEIQTPIDCVTAIYTVLSRRRGYVTSDVPQPGTPAYIVKAFLPVIESFGFETDLRYHTQGQAFCLSVFDHWAIVPGDPLDKAIQLRPLEPAPIQHLAREFMVKTRRRKGMSEDVSGNKFFDEAMMVELAQQTGDLHLQMI
What is the function of this protein?
Splicing factor involved in pre-mRNA splicing and component of the spliceosome.
What are the official names of this protein?
109 kDa U5 small nuclear ribonucleoprotein component GFL, Protein GFA1-LIKE, SNU114 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: TDCD_ECOL6
Sequence: MNEFPVVLVINCGSSSIKFSVLNASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDNVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLHRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAEFA
What is the function of this protein?
Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP.
What are the official names of this protein?
Propionate kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family. TdcD subfamily.
Protein: NCPP_SALAR
Sequence: MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPIAVESGVPEQPFGSEETRTGARNRVANARLLCPEADFWVAIEAGIDDNSTFSWVVIESVELRGESRSATLPLPAVILENVRAGDALGPVMSRYTGIDEIGRKEGAIGIFTAGKLTRSSVYHQAVILALSPFHNAVYR
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: RBFA_BRUSU
Sequence: MARSHDTKGSGGLSQRQLRVGEQVRHALAQVLQRGEIRDDLIERTVISVSEVRMSPDLKIATCFITPLGSADPQAVIKALASHAKFIRGRVAPSLAQMKYMPEFRFRPDTSFDNFSKIDALLRSPEVARDLSHDDDEDGGADEAPRNGDE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXB_ECOSE
Sequence: MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANKL2_CAEEL
Sequence: MGRKSAILAVILAIIYFRSNFSKMSNTPVQETEGPVYVAYSMEDMLKSPRDLYKSVKEVAKFVNSAEGKSMSARFKKFGTPREAMDFLAYGDAPTTPKTVPPVAPTEPNSPFSGVNRIQMNEFKKYVEKGDMENFLRLVDSNPRFLVNTGGDVASIVMEGFRYNALHIAAKAGQTEIIAKILELIQNIDFLIRLYGTGADDVTLRKINILDSYLNTPDKGNSDTPLHFASKFGKIGVVRVLTENSATDRTLLNKSGKSALDCAGERYTGEDKDMVQRDIHLAIEGFYVFLHRNPTTGSTQLTVSQKPPATYSTSPTTATVTVSAQAGPFFTEREARDFAKSWQTAGKELKRTDFDKGWERVGRVLAEQSEAMWRETWHFLGSMELLDLGSEQGLGVLEAFLREKRRGNLRNSEISEISTKKSIFRRGIHARKLDFGILDGEKSAEISENLTPDGSDSADDEDDDDIFYDTFSEIPAAAEKSINDPDDTLGSLTDRFAAISIFSPLPPPPPPQWSNSPNFDYSEGEDSFATPPTTPPPTFVADDEPCKIDNDLFEVLAQISSELISKFPLTQDYVQKLGKLTAHDRSTWRPIDSPARCDSRRKI
What is the function of this protein?
Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of baf-1 during mitotic exit.  Coordinates the control of baf-1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of baf-1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly.  It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex.
What are the official names of this protein?
Ankyrin repeat and LEM domain-containing protein 2 homolog, LEM domain-containing protein 4-like.
What is the protein family that this protein belongs to?
Belongs to the ANKLE2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: RPOB_ACIAC
Sequence: MAPTSTYSYTERKRIRKSFGSRDSVLKVPYLLQMQKDAYTAFLQADMAPQKRTNEGLQAAFNAAFPIVSHNGFVEMKFVEYNLAKPAFDVRECQTRGLTFASAVRAKVQLIIYDRESSTSQSKVVKEVKEQEVYMGEVPLMTDKGSFIINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLNPESILANFFVNDNFRLMDSGAQMEFVADRLKGEVARFDITDKSGKVVVAKDKRITARHTRELEQSGTTHISVPEDFLIGRVVARNIVDGDTGEIVAKANEELTEALLKKLRSAGVQDLQVIYTNELDQGAYISQTLRIDETVDEFAARVAIYRMMRPGEPPTEDAVQALFQRLFYNPDTYDLSRVGRMKFNAKIGRDESTGPMVLSNDDILAVVKILVDLRNGKGEVDDIDHLGNRRVRCVGELAENQYRTGLARIEKAVKERLGQAEQEPLMPHDLINSKPISAALKEFFGASQLSQFMDQTNPLAEITHKRRVSALGPGGLTRERAGFEVRDVHVTHYGRVCPIETPEGPNIGLINSLALYARLNEYGFIETPYRRVVDGKVTDQIDYLSAIEEGKYVIAQANAALDAEGRLTGDLVSAREKGESTLLSAERVQYMDVSPAQIVSVAASLVPFLEHDDANRALMGANMSRQAVPVLRPEKPMVGTGIERVAAVDSGTVVTANRGGIVDYVDATRIVVRVNDDEAVAGEVGVDIYNLIKYQRSNQNTNIHQRPIVKKGDVLAKGDVIADGASTDLGEIAIGQNMLIAFMPWNGYNFEDSILISERVVAEDRYTSIHIEELVVMARDTKLGAEEITRDIPNLSEQQLNRLDESGIIYVGAEVQPGDTLVGKVTPKGETTLTPEEKLLRAIFGEKASDVKDTSLRVDQGSSGTVIDVQVFTREGIQRDKRAQQIIDDELKRFRLDLNDQLRIVEADAFDRIEKLLNGRVANGGPQKLAKGTKIDKAYLASVEKFHWFDIRPAEDEVATQLESIKNALEQTRHSFDLAFEEKRKKLTQGDELPAGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMADGTPADIVLNPLGVPSRMNIGQVLEVHLGWAGKGIGQRIGDMLRDQAKAAEMRKFLEEVYNSRGRKEDLSVLSDDEVMAMAANLTNGVPYATPVFDGASEAEIKDMLKLAYPDDIKERKGLTESRTQAYLYDGRTGERFERPTTIGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVQGRTKVYESIVKGEHAIEAGMPESFNVLVKEIRSLGLDIELERS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: Y439_BORPD
Sequence: MSDTFLEIAYERARQAQQRQMKRRRAAAHRAARGPAPARAPRASPTQRTGTAHEDQALRLLAGAGLVPLARNLHCRAGEIDLVMRDGATLVLVEVRARANPRYGGAAASVGRAKRARLLRCAALLLPDLARRHWGGRIPPVRFDVVAFEAGRADWLPAAFTL
What are the official names of this protein?
UPF0102 protein Bpet0439.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: PCNA2_PBCV1
Sequence: MYIVTTSFCKIQLQMFTIVSDAAETIKKLFVVFNDLVDIANLSFTNEGLSVQSMDTSHVSLVNLKIGKSYFKDYSIAQEATVGIKISNFVRILDCVGNDEITISFTYDNPDELIVKSEYSDFKMKTIDIETEEMEIPEMDIDVLIDADSNIIQKYLKNMAGFGDTVKIYTQDDVVHMKTAGEIGEVDLQIHDQRVEIKGRLTCEFATRYLMTFAKAAGISKRVVIKLLDDQPGIFEYVFDAESDSKISFFLAPKVKDDGDDEEY
What is the function of this protein?
Sliding clamp subunit.  Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication (By similarity).
What are the official names of this protein?
Probable DNA polymerase sliding clamp 2, Proliferating cell nuclear antigen homolog 2, PCNA 2.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: RECF_LISMH
Sequence: MHLESIVLRNFRNYENLELEFSPSVNVFLGENAQGKTNLLEAVLMLALAKSHRTTNDKDFIMWEKEEAKMEGRIAKHGQSVPLELAITQKGKRAKVNHLEQKKLSQYVGNLNVVIFAPEDLSLVKGAPGIRRRFLNMEIGQMQPIYLHNLSEYQRILQQRNQYLKMLQMKRKVDPILLDILTEQFADVAINLTKRRADFIQKLEAYAAPIHHQISRGLETLKIEYKASVTLNGDDPEVWKADLLQKMESIKQREIDRGVTLIGPHRDDSLFYINGQNVQDFGSQGQQRTTALSIKLAEIDLIHEETGEYPVLLLDDVLSELDDYRQSHLLGAIEGKVQTFVTTTSTSGIDHGTLKQATTFYVEKGTVKKS
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMT_CRYNB
Sequence: MDSSDSKAATDEEIRRALKAADLMKILDGKIALGNKSGTKNLGEHKFWKTQPVPQITGSGAPAPIEEGPIDDPKTPADVRQEPGVLPAGFEWSTIDINDEEQSKEVYVLLCENYVEDDDAMFRFNYSREFLLWALTAPGYLPDWHIGVRVQKTKKLVAFISGIKIDIRVRAKTFPAAEINFLCVHKKLRSKRLAPVLIKEVTRRVNLTNIWQAIYTAGVILPTPIGTCRYFHRNLNPPKLVDIGFSPLPRGSTIARLVQQYSVPSHPRIPGFREMKKEDVPQVGALLRRYLDRFDVAQAFRDDDEVEHWLLSGQGKEVGGRRVEQVVWAYVVEDPTTHRITDLISFYALPSTIMKHPKHNLLNAAYMFYYATDVVFPPSSSSANSDVDVDANAGESSVAAVGTGGEDAKTKKKLETRLNALTADILIIAKQAGFDVFNALTLLDNNMFLQEQKFGPGDGYLNYYLYNWNCAPIDGGHHSTTAKQGSKIGVVML
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
What are the official names of this protein?
Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, NMT, Peptide N-myristoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.