PharMolix/UniProtQA huggingface dataset:
Protein: VPS10_BLAGS
Sequence: MILRRLLLAAGSLLLASAFTSAKKADGPKITVTKFKHEPVNLFYFDDSDVVMLQDGNNGDVYVSRNAGTKWDIVDVGEMKGQAWSLMPHPMDRTKAYVLGKGGKHWVTNDQAMTWREFTVDAELSPYQLPLVFHGKDSNRVMLQGIKCSGRDCVERTYYTTDGFQTLHLLMEKGRHCAWAVSTPMFGDGLDLPKEVNDRIFCVVSGLHSQWPEDNRLLYSDRFFKDDSGIEAGLDSGRAVSGVIRTASAKRHLLAATKSRRTNELALFVTDDASGWHRAEFDGQRIEEDAYTILESTNYSLQVDVVSTDSSAMGTLFTSNSNGTYFTRNIEHTNRNRQGLVDFEKIATIQGIILVNTVKNWEDVEKSSVVEKKIVSRISFDDGRTFQPLKAGKQDLHLHSVTDATNYGRVFSSPAPGLVMGVGNTGGHLKDYSDGDLYISDDAGINWKKALSDAHKYEFGDQGSVIVAVYDEGRTNKISYSFNHGKSWEKASLPLPDDVKIRAKILTTMPDSTSLKFVLVGSAKADSDVEHYVIAIDFAEMEERTCVDPDFEKWPARLNEKQEPDCLMGHKQFYRRRKADANCFIKKKFEDPIPNFEPCKCTEEDFECDFNFIRSEDGKSCVPARSLLAPEGACKNPDDKYTGSSGFRLIPGDACIKKGGLELDKPIERVCSDTMKTPAAGEIAVEKTFFTADNYRDYFYLERTGSSRGDDETVIMITSEQEIFISRDHGKRWKRIFEAETITRIEPHRYFNDVAYFLTNSGEGWYTLDRGENFRKFKAPLPPNQDKLPALSFHPDRRDWLIWTGAEECNGSGGQCHSVAYYTTNRGAEWHFLMRYVRRCEFIKRDARGSSDKIVFCEQYEDENPSSKHLQLISSEDWFAEKKVHYNNILDFATMQEFIIVAIRGEKPQDSLSVGVSIDGKTFADAELPANVKIPIQRAYTVLESRTHAAFLHVTVNNLEDHEYGSLIKSNSNGTSYVLSLSAVNRNSRGYADFEKMQGLEGVAMANVVANVDDVEKGAAKKYRTMITHNDGAEWTLLAPPGKDSEGRAYGCSTKGGKPTKACALHLHSYTERVDPRDTYSSPGAVGIMIGTGNVGEYLTPKSSADTFITRDAGISWEEAKKGKYQWEYGDSGSIIVLVPESTPTKTLLYSLDEGRSWKEYQFSEVEMQIRDISTVPSDTSRNFLLWGNEVGQGKKPGLATVNIDFSGLKERSKQCVLNEEKPEADDYYLWEPKHPLQPNGCLFGHRAKYHRKRPEKDCYNGREIQHLDSIGDICECTRSDYECDYNYEPQTDGTCARVPGLEPLDPKLVCTEDPKAIEWYEPTGYRRIPLTKCQGGKQLNHIIAHPCPNKEEEFEKKHPRLRGIGLFFAIVIPIGLAAAVGYYVYQHWDGKFGRIRLGETGSGGFFDRDSPLISIPVTIVAGIVAVATALPLLVSSLWRSLGGYIRVPGSGSSRQPYSSRGAFAARRGDYVGVVDDEDELLGTDDLEDDEEGEERNGQV
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: O1627_CONCL
Sequence: MKLTCVLIAAMLLLAVCQLDSADATETGCKKDGSWCWIPSECCIESCLITCWY
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Cal6.27, O1_cal6.27.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYV_YEAST
Sequence: MNKWLNTLSKTFTFRLLNCHYRRSLPLCQNFSLKKSLTHNQVRFFKMSDLDNLPPVDPKTGEVIINPLKEDGSPKTPKEIEKEKKKAEKLLKFAAKQAKKNAAATTGASQKKPKKKKEVEPIPEFIDKTVPGEKKILVSLDDPALKAYNPANVESSWYDWWIKTGVFEPEFTADGKVKPEGVFCIPAPPPNVTGALHIGHALTIAIQDSLIRYNRMKGKTVLFLPGFDHAGIATQSVVEKQIWAKDRKTRHDYGREAFVGKVWEWKEEYHSRIKNQIQKLGASYDWSREAFTLSPELTKSVEEAFVRLHDEGVIYRASRLVNWSVKLNTAISNLEVENKDVKSRTLLSVPGYDEKVEFGVLTSFAYPVIGSDEKLIIATTRPETIFGDTAVAVHPDDDRYKHLHGKFIQHPFLPRKIPIITDKEAVDMEFGTGAVKITPAHDQNDYNTGKRHNLEFINILTDDGLLNEECGPEWQGMKRFDARKKVIEQLKEKNLYVGQEDNEMTIPTCSRSGDIIEPLLKPQWWVSQSEMAKDAIKVVRDGQITITPKSSEAEYFHWLGNIQDWCISRQLWWGHRCPVYFINIEGEEHDRIDGDYWVAGRSMEEAEKKAAAKYPNSKFTLEQDEDVLDTWFSSGLWPFSTLGWPEKTKDMETFYPFSMLETGWDILFFWVTRMILLGLKLTGSVPFKEVFCHSLVRDAQGRKMSKSLGNVIDPLDVITGIKLDDLHAKLLQGNLDPREVEKAKIGQKESYPNGIPQCGTDAMRFALCAYTTGGRDINLDILRVEGYRKFCNKIYQATKFALMRLGDDYQPPATEGLSGNESLVEKWILHKLTETSKIVNEALDKRDFLTSTSSIYEFWYLICDVYIENSKYLIQEGSAIEKKSAKDTLYILLDNALKLIHPFMPFISEEMWQRLPKRSTEKAASIVKASYPVYVSEYDDVKSANAYDLVLNITKEARSLLSEYNILKNGKVFVESNHEEYFKTAEDQKDSIVSLIKAIDEVTVVRDASEIPEGCVLQSVNPEVNVHLLVKGHVDIDAEIAKVQKKLEKAKKSKNGIEQTINSKDYETKANTQAKEANKSKLDNTVAEIEGLEATIENLKRLKL
What are the official names of this protein?
Valine--tRNA ligase, mitochondrial, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
[Isoform Cytoplasmic]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform Mitochondrial]: Mitochondrion.
Protein: RS9_MYCTO
Sequence: MTETTPAPQTPAAPAGPAQSFVLERPIQTVGRRKEAVVRVRLVPGTGKFDLNGRSLEDYFPNKVHQQLIKAPLVTVDRVESFDIFAHLGGGGPSGQAGALRLGIARALILVSPEDRPALKKAGFLTRDPRATERKKYGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: Y945_BACCQ
Sequence: MTKNIHDVAYELQKAIAENDDFKTLKESYAAVQADAASKNLFDEFRTMQLSLQQKMMQGQEITEEDNQQAQEVVVRIQQDAKITKLMETEQRLNVVIGDVNKIIMKPLEELYSAQQQA
What are the official names of this protein?
UPF0342 protein BCQ_0945.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: PBN1_ASPOR
Sequence: MRRRITFVQRPETPFSLDQAVLTPDALALHGIDGAREERATFSVDELPEELSDVLKQCHQLHVRWASERRYDAVAPFSSRVSPGLHVFYTPVDGSSEENKLKSLCALLKRAFDYGLKCKSPETLEESFITPPILSTRFASTAAFQYHSLLPTLDNLVAYIENKICSSSDEQCLRYAASIRSADSVDINYDSISHSLTVLGYWSQSPKNGWTDEIRRHAAGTDQVEVGLLGTEAATEPEDIKMGGLLAVVGKDDQLSMLSSGLPSEFGVAYGYGTDDSWAEPTLFSFPSRHQPLPEDATYSISFTSPTGLHPTMTISMPPSSLNSPPAPPDATCALHTYLTLPSTIFGDKYQLSTTDPLFLDSHNLVALHAVAGETDLEAPDWFVSRWGSNWLLELATPSESDQVPEEWNVTIPLHLRYLRPSESGYRSASVPWPVVFWACTAEDGTKMGVNPFDRVNLGWEGLFGTRTMFYQLHPSSDRLVEELEVPVLQLDDKGFFQSKAIELGTMIVIGLGSLWVLWKLGAIAWSSGTRPQRKSTKQKKSE
What is the function of this protein?
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum.  Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.  Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity).
What are the official names of this protein?
Protein pbn1.
What is the protein family that this protein belongs to?
Belongs to the PIGX family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: GGAB_BACSU
Sequence: MNEKSFNYDFSVIMPIYNVELYLTEAIESIINQTIGFENIQLILVNDDSPDKSEIICKEYAQKYPNNIVYAKKQNGGVSSARNYGLKYAEGRYIQFLDPDDLVSEGTFENVLNFFDEHKNEIDIVAIPIFFAEGRTGEHNLNNKFSSTRILDVEKEPHHILTHCCSTFIKKDALKNIRFDENCKIGEDAKLVNLIISQKKKYGLVKEAKYHYRVREDGSSAMQTAKANKNWFNHSLITFSKNLIDIIKNHEQKIPLFLQYMVMHDLKWKLLIKDISETPLDENEYSEFLTLIREVLSYIDDDVIIETKSVSHFYLYHALKIKHGENYSRYVYERETEQDYYLYREGKIVSKLSDQTLTIEILEENEDSIHIEGFWSSLFNSKGFKFYAKIGETKIKAKNIKRQHNDYISLGEVIKKYPGFSIDIPKGHLADNHHIEFFITKGKKRKLTKLRFFKYSGLSNDLYNTYVAKKDYIFYYNYKKLMFKKNNFKNRFIKEFRFLKSLHKSGEKSKKRKSAIKKALMARMVHHVFTIFNRKPVWLFIDRQDKADDNAEHLFKYAINKNDGVKKYFIIKKDSKDYDRIKKYGKVIPYRSFRHKILTLSSSKVISTHADIWVVNPFFNMEIYFRDLFNFEFIFLQHGITMADHSEWLNKYNKNIKLLVTSAKPEYRSIVKGNYNYKKENILLGGFPRYDNLKKSEGEKQLLIMPTWRKDIVLPKDQAKGVRPYNPKFKDSEYFSRYNALINDERLIEFAKKNNYKITFFPHPDIQQQIVDFEKHDYVEFADYNSSYQMLFNSSNIMITDFSSVAFDFAYEKKPVIYYQYEKSYHFKLDYYDYKKMGFGDVLENHNSLVDKVIYYMKNNSRMEDKYRKRVDNFFAYTDKNNRNRIYNAILELDNNKVAK
What is the function of this protein?
Involved in the biosynthesis of galactosamine-containing minor teichoic acid, a non-essential cell wall polymer in B. subtilis 168.
What are the official names of this protein?
Minor teichoic acid biosynthesis protein GgaB.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: RL16_CHLCH
Sequence: MLMPKRVKYRKTQRGRMKGNAGRGTSVAFGSFGLKAMEPAWITSRQIEAARIAMTRYMKRDGKVWIRIFPDKPVTQKPAETRMGSGKGSPEFWVAVVKPGRVMFEADGVSKEIATEAFRLAAKKLPIKTKFIIRPDYEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DXR_XANC5
Sequence: MAGSSLRQVAVFGATGSIGASALDVIARHPERLRASLLSAGSKVDELLALCATHRPAHAVIADAALYPALRDGLRALGLATQAHAGAEALDALASGDVCDTVVAAIVGAAGLPSTLAAARAGKRLLLANKESLVLAGELLTRTAAAAGAEIIPIDSEHSAIFQCLRSCDASRGVRRVILTASGGPFRGRDRAALAAVTPAQAVAHPKWSMGPKISVDSATMMNKGLEVIEAHHLFGLPGEQIDVLVHPQSLVHSLVEFVDGSTLAQLGLPDMRTTLAVGLAWPERVDSGVGGLDLLRQGRLDFEAPDTAAFPCLRLAWDALRAGGTAPAILNAANEVAVSAFLQGQVGFLAIPALVEHTLTTLPRHNADSLDTLLFADAQARQITERALAHHALHA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: M4K2_MOUSE
Sequence: MALLRDVSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILRECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHHLHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVERKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNFHHFLKLALTKNPKKRPTAERLLQHPFTTQHLPPALLTQLLDKASDPHLGTLSPEDSELETHDMFPDTIHSRSHHGPAERTPSEIQFHQVKFGAPRRKETDPLNEPWEEEWTLLGKEELSGSLLQSVQEALEERSLTIRPALELQELDSPDDAIGTIKRAPFLGLPHTESTSGDNAQSCSPGTLSAPPAGPGSPALLPTAWATLKQQEDRERSSCHGLPPTPKVHMGACFSKVFNGCPLQIHAAVTWVHPVTRDQFLVVGAEEGIYTLNLHELHEDTMEKLISQRCSWLYCVNNVLLSLSGKSTHIWAHDLPGLFEQRRLQHQAPLSIPTNRITQRIIPRRFALSTKIPDTKGCLQCRVVRNPYTGSTFLLAALPASLLLLQWYEPLQKFLLLKNFSSPLPSPAGMLEPLVLDGKELPQVCVGAEGPEGPGCRVLFHVLPLEAGLTPDILIPPEGIPGSAQQVIQVDRDTVLVSFERCVRIVNLQGEPTAALAPELTFDFTIETVVCLQDSVLAFWSHGMQGRSLDTNEVTQEITDETRIFRVLGAHRDIILESIPTDNPGAHSNLYILTGHQSSY
What is the function of this protein?
Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway (PubMed:8643544).  Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser extent of the p38 MAPKs signaling pathway (By similarity).  Required for the efficient activation of JNKs by TRAF6-dependent stimuli, including pathogen-associated molecular patterns (PAMPs) such as polyinosine-polycytidine (poly(IC)), lipopolysaccharides (LPS), lipid A, peptidoglycan (PGN), or bacterial flagellin (By similarity).  To a lesser degree, IL-1 and engagement of CD40 also stimulate MAP4K2-mediated JNKs activation (By similarity).  The requirement for MAP4K2/GCK is most pronounced for LPS signaling, and extends to LPS stimulation of c-Jun phosphorylation and induction of IL-8 (By similarity).  Enhances MAP3K1 oligomerization, which may relieve N-terminal mediated MAP3K1 autoinhibition and lead to activation following autophosphorylation (By similarity).  Mediates also the SAP/JNK signaling pathway and the p38 MAPKs signaling pathway through activation of the MAP3Ks MAP3K10/MLK2 and MAP3K11/MLK3 (By similarity).  May play a role in the regulation of vesicle targeting or fusion (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase kinase 2, Germinal center kinase, GCK, MAPK/ERK kinase kinase kinase 2, MEK kinase kinase 2, MEKKK 2, Rab8-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Basolateral cell membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein.
Protein: URE1_CYTH3
Sequence: MSYILSRKSYADMFGVTTGDKITLGDTNLLVRVEKDLTVYGEECKFGGGKVLRDGMGQASGYKSDDVLDLLITNALIIDYTGIYKADIGIKNGHIKAIGKSGNPHIMPGVHPDMIAGTVTEVIAGEGMIITAGGIDNHIHYICPQQMNEALASGITTFIGGGTGPATGTKATTCTPGAFHIEMMLKATDNIPMNIGFLGKGNTSHPEEIEEQIKAGALGLKLHEDWGTTPAAIDNCLSVAEKYDVQVCIHTDTLNESGFVESSRAAFKGRTIHTYHTEGAGGGHAPDIIVLCGDPDVLPSSTNPTKPFTVNTIDEHLDMLMVCHHLDRNIPEDVSFAESRIRGETIAAEDILHDMGALSMLSSDSQAMGRVGEVICRTWQTAHKMKEQRGLLEEDKQIDADNFRVKRYIAKYTINPAIAHGCSHVIGSVEVGKLADLVVWQPDFFGSRPELILKGGVIVQAQMGDPNASIPTPQPFFSRPMFGAMGKATGATSLAFVSAASEETVNGYGLNKKVTPVVGCRSVKKKDMKLNDFLPDIKVDAETYKVTVNGEWITCAPAKKLPLAQLYNLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CONO_CONTE
Sequence: CFIRNCPP
What is the function of this protein?
Targets vasopressin-oxytocin related receptors.
What are the official names of this protein?
Conopressin-Tx.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAB_IDILO
Sequence: MSKKLYIKTWGCQMNEYDSTKMAELLHSTHGYDVAEEAEDADLILLNTCSIREKAQEKVFHQLGRWKNLKKNNPNLLIGVGGCVASQEGNEIRARAPFVDIIFGPQTLHRLPEMVNQVSETHAPMVDVSFPEIEKFDRLAEPKADGASAFVSIMEGCSKYCSFCVVPYTRGEEVSRPVDDVIYEIAQLAEQGVREVNLLGQNVNAYRGEHYDGEVCRFAELLHLVAAIDGIDRIRYTTSHPVEFTDDITEAYKTIPELVSHLHLPVQSGSDRILTMMKRGHTALEYKSKIRALKKARPDIAMSSDFIIGFPGESDADFEATMDLIQSIDFDMSFSFIYSARPGTPAADLPDDISEETKKKRLQLLQQRLNQQSMAHARRMLETEQRILVTGPSKKNPMELTGRTENNRVVNFVGQPHMIGQFVDVRITEVLPNSLRGELIREEADMGLRVDTAPEIILQRGKSSEPDELGVVRMPRQAS
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_SHIB3
Sequence: MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MPND_MOUSE
Sequence: MAAPESLSPGATAEEAPEEDEDDAEAEDPERGTGSGGRSGSLGGSGGGTAGPGMALGGALTRRAVTLRVLLKDELLEPGEGVLSIYYLGRKFTGDLQLDGRIVWQETGQVFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKAAWLRRHQLHMPVATADESPTSEGEEEELLLEEEEEDVLAGVSSEDKGHRPPGKGSLEPEATPPGKRMDKVPVPIRYCMLGSRDSARNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHCHLTRSEVVGYLGGRWDINNQMLTVLRAFPCRSRLGDTDTAATVEEEIYQVLFLRGLSLVGWYHSHPHSPAVPSLQDIDAQMEYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKICPFWVMPPPEQRPSDYGIPMDVEMAYVQDSFLTNDVLQEMVMLAEFYKGAPDLVKFQEAWSPEHTYLDKLKMSLASRTPKDQGMCHVLEQVCSVLKQGS
What is the function of this protein?
Probable protease (By similarity).  Acts as a sensor of N(6)-methyladenosine methylation on DNA (m6A): recognizes and binds m6A DNA, leading to its degradation (By similarity).
What are the official names of this protein?
MPN domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67 family.
Protein: RECF_ECOLI
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNUC_MAGMM
Sequence: MSDTSLTHCSEVLLTARNLCADRGGRRVLEGIDLSIGAGEVVTIIGPNGAGKSTLLKVLLGVEPYSEGQVIRKANLCVGYVPQRMPVDAILPMTVQRMLRLAKEVDETAMLAVLEETGVAHVLHAPLQGLSGGEFQRVLLARAMLRNPQLLVLDEPVQGVDYSGEVALYQLIGALRKRHGCGVLLVSHDLHMVMRDTDRVVCLNRHICCTGTPDHVSGHPEFARLFGDQALQTLALYQHHHHSCTHHMPVDVAIDPQEQA
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPF3_HUMAN
Sequence: MATVIHNPLKALGDQFYKEAIEHCRSYNSRLCAERSVRLPFLDSQTGVAQNNCYIWMEKRHRGPGLAPGQLYTYPARCWRKKRRLHPPEDPKLRLLEIKPEVELPLKKDGFTSESTTLEALLRGEGVEKKVDAREEESIQEIQRVLENDENVEEGNEEEDLEEDIPKRKNRTRGRARGSAGGRRRHDAASQEDHDKPYVCDICGKRYKNRPGLSYHYAHTHLASEEGDEAQDQETRSPPNHRNENHRPQKGPDGTVIPNNYCDFCLGGSNMNKKSGRPEELVSCADCGRSGHPTCLQFTLNMTEAVKTYKWQCIECKSCILCGTSENDDQLLFCDDCDRGYHMYCLNPPVAEPPEGSWSCHLCWELLKEKASAFGCQA
What is the function of this protein?
Acts as a regulator of myogenesis in cooperation with HDGFL2 (PubMed:32459350).  Mediates the interaction of HDGFL2 with the BAF complex (PubMed:32459350).  HDGFL2-DPF3a activate myogenic genes by increasing chromatin accessibility through recruitment of SMARCA4/BRG1/BAF190A (ATPase subunit of the BAF complex) to myogenic gene promoters (PubMed:32459350).
What are the official names of this protein?
Zinc finger protein DPF3, BRG1-associated factor 45C, BAF45C, Zinc finger protein cer-d4.
What is the protein family that this protein belongs to?
Belongs to the requiem/DPF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMH_RHOPA
Sequence: MKPSDARHIPVLGPEAVGLLAPRAGGIYVDGTFGAGGYTRLILETAGSRVIAIDRDPSAIAGGADLVTEAGGRLTLVQDRFSNLADVCAAQGAATVDGVVMDIGVSSMQLDQAERGFSFRFDGPLDMRMGRDGPSAADVVARASETDLANIIYIFGEERYSRHVARAIVAARSETPITTTKALADIVAKVVRAKPGEIHPATRTFQGLRIFVNEELDELHQALDAAERVLKPSGRLAVVSFHSLEDRIVKTFLAERSKTGGGSRHLPEVAQAAPSFTLLSKRPIVAGDAEVAANPRARSAKLRGAERTESPAHAAGDLPGWPTLASVMRAGR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_SYNP6
Sequence: MHLSEITHPNQLHGLSVAQLEQIGHQIREKHLQTVAATGGHLGPGLGVVELTLALYQTLDLDRDKVVWDVGHQAYPHKLLTGRYHNFHTLRQKDGIAGYLKRTENRFDHFGAGHASTSISAALGMALARDAQGEDYRCVAVIGDGSLTGGMALEAINHAGHLPKTRLLVVLNDNDMSISPNVGALSRYLNKIRVSEPMQLLTDGLTQGMQQIPFVGGAITQGFEPVKEGMKRLSYSKIGAVFEELGFTYMGPVDGHNLEELIATFREAHKHTGPVLVHVATTKGKGYPYAEEDQVGYHAQNPFDLATGKAKPASKPKPPSHSKVFGQTLTTLAKSDRRIVGITAAMATGTGLDILQKALPKQYIDVGIAEQHAVVLAAGMACDGMRPVVAIYSTFLQRAFDQVIHDVCIQKLPVFFCLDRAGIVGADGPTHQGMYDIAYLRLIPNMVLMAPKDEAELQRMLVTGIEYDGPIAMRFPRGNGIGVPLPEEGWESLPIGKAEQLRQGDDLLMLAYGSMVYPALQTAELLNEHGISATVINARFAKPLDEELIVPLARQIGKVVTFEEGCLPGGFGSAIMESLQAHDLQVPVLPIGVPDLLVEHASPDESKQELGLTPRQMADRILEKFGSRQRIGAASA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RL18A_NANEQ
Sequence: MEKKVFVVEGYAKKGSLKFRFKKYFIALKKEDAIFYTYSILGSNHKLKKTQIHIERVYELDPEKDKDKLPDKRLLAFF
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: DEOC_GLOC7
Sequence: MTLTDSDIELAAYIDHALLIPTATPQQLEQCCAEADQFHFPTVCIYPVAVKQAVQLLHNKKVRVCAVIGFPAGATTSTTKLYEAREAAENGATELDVMINLGWLKAGKSEDIYREIASICEETGLTVKAILETNVLTDTEKRLAAEICMDAGASYLKTSTGWFGGATIADVRFLKQVTKGQVGIKASGGIRTPEQALALIEAGANRLGTSKGPDLIRQLQSPRETKPPEDQ
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GST1_ASCSU
Sequence: MPQYKLTYFDIRGLGEGARLIFHQAGVKFEDNRLKREDWPALKPKTPFGQLPLLEVDGEVLAQSAAIYRYLGRQFGLAGKTPMEEAQVDSIFDQFKDFMAELRPCFRVLAGFEEGDKEKVLKEVAVPARDKHLPLLEKFLAKSGSEYMVGKSVTWADLVITDSLASWESLIPDFLSGHLQLKKYIEHVRELPNIKKWIAERPKTPY
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Can also function as a GSH peroxidase.
What are the official names of this protein?
Glutathione S-transferase 1, GST class-sigma.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Sigma family.
Protein: RPOA_CAMJ8
Sequence: MRNITTSAYTPTEFTIENISDTVAKISAWPFEIGYGITLAHPLRRLLYTSTIGYAPTAIHIDGVAHEFDSMRGMLEDVALFIINLKKLRFKIKGESNKEIVEFSFKGSKEIYGKDLNNDQVEVVNKDAYLATINEDAELKFTLIVEKGIGYVPSEEIKELINDPKFIALDAFFTPVREATYDIEKVLFEDNPDYEKVVLTVTTDGQITPNEAFQNALEAMYKQLSVFDKITNVRSVIKNQATSNELENTKLLQNITDLNLSARSYNCLEKAGVVYIGELALMSVSELAGLKNLGKKSLDEIKNIMESIGFPVGTSKLSDNKEILKNKIAELKAQNEG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RS14_PSEAE
Sequence: MAKESMKNRELKRQLTVAKYAKKRAELKAIIANPNSSAEERWNAQVALQKQPRDASASRLRNRCRLTGRPHGFYRKFGLSRNKLREAAMRGDVPGLVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.