PharMolix/UniProtQA huggingface dataset:
Protein: FPG_SHISS
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SPAP_SALTY
Sequence: MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
What is the function of this protein?
Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.
What are the official names of this protein?
Surface presentation of antigens protein SpaP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH10_HYDCU
Sequence: MNIKPLHDRVVVRQVEEQKESTGGILLPGSAQEKENLGEVVAVGPGKAADNGSIIPMTVKVGDKVMFGQYSGQEVKDDAGKPLKVMREDDIIAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMCAL_STRPZ
Sequence: MTVTGIIAEFNPFHNGHKYLLETAEGLKIIAMSGNFMQRGEPALIDKWIRSEMALKNGADIVVELPFFVSVQSADYFAQGAIDILCQLGIQQLAFGTENVIDYQKLIKVYEKKSEQMTAYLSTLEDTLSYPQKTQKMWEIFAGVKFSGQTPNHILGLSYAKASAGKHIQLCPIKRQGAAYHSKDKNHLLASASAIRQHLNDWDFISHSVPNAGLLINNPHMSWDHYFSFLKYQILNHSDLTSIFQVNDELASRIKKAIKVSQNIDHLVDTVATKRYTKSRVRRILTYILVNAKEPTLPKGIHILGFTSKGQAHLKKLKKSRPLITRIGAETWDEMTQKADSIYQLGHQDIPEQSFGRIPIIIKNERLN
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNS1_SCHPO
Sequence: MVKRRTVKYFLRRILALFVLCVPIYYLYTTVQRPPGYTKLKGSTRRKALIKKTFIESWTDYETYGWGKDEYYPIIKRGRNYLRKGMGWMIIDSLDTMMIMGLDEQVLRAREWVNNSLTWNQDDEEVSVFETTIRILGGLLSSYHLSQDKLYLDRAVDLADRLLAAYNTSTGLPRSNVNLGTRKSRKRTREYFVSTAESGTVQMELRYLSYLTGDPKYWITADKTMEVLLGDATWSHTGLVPITVNLITGAYVGRNIRLGSHGDSYYEYLLKQDLQLFSSGTVYRKAFDLSVDGIIEYLLNYTTPNHFAYIAELPGGLEHAQLPKMDHLVCFLPGTLMWGATNGTSLEAARTSKNWGTRQERDVKLAQELMRTCYEMYNMTATGLAPEIVFFDVDQTKNEIYSKRRDQHNLMRPETVESLFILYRITRDEIYREWGWNIFVSFLRYSRLPGRDAFTCLDSVESKKVKDQRDKTESFWFAETLKYLYLLFEDDFSILPLTNYTFNTEAHPFPNIENNMDLYTV
What is the function of this protein?
Involved in glycoprotein quality control as it is important for the targeting of misfolded glycoproteins for degradation.  It trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2) with low efficiency.
What are the official names of this protein?
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, ER alpha-1,2-mannosidase, Man(9)-alpha-mannosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RPOZ_LACP3
Sequence: MIIYPSIDKLLEKVPSRYSLAVLAAKRAHELESGDLKMLSDYKSDKSVGKALEEIAAGDVIIDPKSKMLERDAEKLDRKDQE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PSAB_BIGNA
Sequence: MKLRLFTSGILGDDKRSMETTQDLWFFRIVHDFFATFEGVSVYQKIFASHFGQIALIFLWASGNLFYVSSQGNFEQWVSDPLHTRPIAHAIWDPQFGQSAVAAYTRAGASGPVTLSTSGLYQWWYTIGMRSNDDLSTASMFLLILSVLFLIAGFIHGYVPLFKPSLAFFKDAESRLNHHLSALFGVSSLAWTGHLIHVAIPESRGQHIRWNNYLSTLPHPDGLAPFFSGNWSAYSTNPDTFNHVFGTSNGAGSAILTFQGGLNPQTGSLWLTDIAHHHLAIAVLFIVAGHMYKTNWSIGHNLQELVEGHNIINGRFNHKGLYQTVNTCLNLQLALALAAVGTICSLVAQHMYSLPAYAYMAQDYVTQAALYTHHQYIAGFIMCGAFAHGTIFLVTEYDPEINADNVLARFLENREVIISHLSWVCLFLGFHTLGLYVHNDVMLAFETPEKQILIEPIFAQYIQAAQGKSSYDFNVLLSSSVSDAYLIPTQSANKGIWLSGWLNSINNNTNSLFIEIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKRFGYGFPCDGPGRGGTCDISAWDAFYLAIFWMLNTIGWVTFYWHWKHLGIWQGNTKQFYESSTYLMGWLRDYLWLNSSQLINGYNPLGMNALSVWSWMFLFGHLIYATGFMFLISWRGYWQELIETLVWAHDRLPIVLWPEKPVALTIVQARFVGLIHFTVGYILTYAAFLIASTSGKFS
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y460_BACAH
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWEETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHANYWFNVIGMLREEGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAQLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BALH_0460.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: OBG_FLAPJ
Sequence: MTEGNFVDYTKIYVSSGKGGKGSTHLHREKFIEKGGPDGGDGGRGGHVYLVGEKSLWTLFHLKFARHVKAGHGGDGGSSRSTGSDGEDKYIEVPLGTVVRDKETNEILFEITEHGEKRIIAEGGKGGLGNWHFRSSTNQTPRYSQPGLPAQEADIVLELKVLADVGLVGFPNAGKSTLLSVLTSAKPKIADYPFTTLKPNLGIVAYRDYQSFVIADIPGIIEGAAEGKGLGHYFLRHIERNSTLLFLVPADADDIKKEYDILLDELRRYNPEMLDKDRLIVVSKCDMLDEELQVEMKKQLDKDFAGIPYLFISSIAQQGLVELKDKLWAMLNVEA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLRK_ECOLI
Sequence: MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQAALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHAGVLPDDKLYQALRQDLHNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSRGQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSSKNTK
What is the function of this protein?
Member of the two-component regulatory system GlrR/GlrK that up-regulates transcription of the glmY sRNA when cells enter the stationary growth phase.  Activates GlrR by phosphorylation.
What are the official names of this protein?
Sensor histidine kinase GlrK.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYY_WOLTR
Sequence: MKHKSEFLNFIQERGYLCQCTNIEGLDQLLLQNNYVVAYIGFDCTASSLHVGSLIQIMMLRHLQKFGYKPIVLLGGSTTKIGDPSGKDKARSVLPIEDINQNISGIKKALKKMVYFNDGKAGAIIVNNADWLDSIKYIDFLRDIGAHFSVNRMLSFDSAKTRLDREQNLSFLEFNYMLLQAYDFAELNKKYGCRLQIGGSDQWGNIVNGIELGKKLNLPELFGLTTPLLLSAQGKKMGKTESGTVWLDGDMLKPYDYWQYFRNIDDQDIGRFLRFFTDLPIDEIKKLESLKNQEINEAKKALATEVTKICHGDKEAELAQSSAVSVFENGDSSLLPDYTITKKQVANGISLIDLLHDIGLEPSKGAAKRLIQGNGCKVNDYTINDINYIINSKSFKDQSFIKLSAGKKRHIKVMVS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURP_PYRAE
Sequence: MALKPTMSQLLKNYDLERLAISTVASHTALQILRGAKKYGFRTIAVARGEAVAQFYRQFPFIDEVWVGDFANFRKTAEKLAANNAVFIPHGSYVEYVGWRQALEAPVPTLGCRELLRWEADQFKKMSLLEKAGIPIPRIYKTAEEVEGPVIVKLFGAKGGRGYFVARDRRELAERLKRVTEDYIIQEYLFGVPAYYHYFSSPVYSRLEIFGADIRYESNVDGRTFGWAEPTFVVVGNLPMVLRESLLPTIYTYGVQFLKAVEEAVGCKLAGPFCLESIIKDDMSIVVFEFSGRIVAGTNIYMGYGSPYSVLYFDKPMDMGERIAHEIKEAVKRGKIEHLFT
What is the function of this protein?
Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.
What are the official names of this protein?
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase, 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MUTS2_STREM
Sequence: MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQAYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLEVKKLLQVSAEACRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISNKEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTVYIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRAKYLYMQAKQAAVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGKTIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHIVEILKQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYGIETAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATNHDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAALEAREIVDMALAESESILSQLHEKAELKPHEIIEAKHRLKQLVPEQSLSQNKVLKKAKKWRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQPKKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGTGVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: TRUB_STRA3
Sequence: MITGIINLKKEAGMTSHDAVFKLRKILHTKKIGHGGTLDPDVVGVLPIAVGKATRVIEYMTESGKIYEGEITLGYATSTEDSSGEVISRTPLTQSDLSEDVVDHAMKSFTGPITQVPPMYSAVKVNGKKLYEYARSGEEVERPKRQITISEFRRTSPLYFEKGICRFSFYVSCSKGTYVRTLAVDLGIKLGYASHMSFLKRTSSAGLSITQSLTLEEINEKYKQEDFSFLLPIEYGVLDLPKVNLTEEDKVEISYGRRILLENEADTLAAFYENRVIAILEKRGNEFKPHKVLL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: GTR12_MOUSE
Sequence: MVPVENTEGPNLLNQKGREAETEGSCGASGGGHPACAGGPSMFTFLTSVTAAISGLLVGYELGLISGALLQIRTLLALTCHEQEMVVSSLLIGAFLASLTGGVLIDRYGRRLAIILSSCLLGLGSLVLIMSLSYTLLIMGRVAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEESAGKVLRKLRVISDTTEELTLIKSSLKDEYQYSFWDLFRSKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVVSTIPATLLVDHIGSKTFLCIGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLNQSLEEFVFYATGNLSISNSSLREHFKRITPYSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEHQGVTDTAVVPAAYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNLLISLTFLTVTDLIGLSWVCFIYTIMSLASLAFVVLFIPETKGCSLEQISVELAKANYVKNNICFMSHHQEELVPTQLQKRKPQEQLPECNHLCGRGQSQRPSPDT
What is the function of this protein?
Insulin-independent facilitative glucose transporter.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 12, Glucose transporter type 12, GLUT-12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Localizes primarily perinuclear region in the absence of insulin.
Protein: FBK56_ARATH
Sequence: MVQISDLPRDLTEEVLSRIPVTSMRAVRFTCKKWNTLSKDRSFTKKHLRGARAAAKKKQTKEFQVIMMIQFRVYLYSVNLLNPSIERIGKLISLDVEDHVDISKIFHCGGLLLCITKDISRLVVWNPYSGQTRWIKPRNSYHRLDRYALGYEEKNKSCRCYKILRFMDDYEDDRALRLIREFEIYDLNSDSWKVVNVTPDWDVEFYHRGLSLKGNTYWFAQEKLPPLPRGRVITISDMADFLLCFDFTRERFGPRLPLPFHSFVEDTVTLSSVRDKKLAVLFQPCSASTVKIWISRKIEPNAVSWRKVFLAVDMKSLTGFQFDINAASFFVDEKKKVAMVLDKDRFSYKFTRNIAYIIGKKGYFEKVDLGESTVSSCASLVCSYVPSSVQI
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
F-box/kelch-repeat protein At3g16740.
What are the subcellular locations of this protein?
Nucleus.
Protein: APT_ECOSM
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDGC_ECO45
Sequence: MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TILS_FRATO
Sequence: MSISKSLVLNEIKKFSPSHIIIGYSGGVDSSVLLNISKELDIPLIAIYINHNLHRDSLKWQIHCQQTCQKYNLQFISHSLDKVPKGESFEAWASKQRMAFFQKIMQQYSKPLLLLGHHQDDQAETFLIQAIRGSGLAGLASIPHYKELHHGGVLRPLLKYSKIDIEGFAKLNNISYIYDDSNEDIKYRRNLIRNQIIPILQQVNPNISQTLSRSANICAESNNILQKLLTERLQSISQDTNLIISELIKLDDDIQKNLLHLWFKQNTQQSLKSKQIKELHLAVNNPSTGWQIDISNYYQIHIQYNQLIIKYPTTINDISKEDIISWLSKNLNEEIDLTKIVIRDRKPDDKCKYRGRNKPNKLKILFQELQIPTTERSKAKIILKDQQIIAVYPFFICG
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_PSEMY
Sequence: MSRVCQVTGKGPVTGNNISHANNKTRRRFLPNLQHHRFWVESEKRFVRLRVSAKGMRVIDKRGIDVVLAELRARGEKV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HUTI_ANAD2
Sequence: MSRPTATLVLRNAVVATCDRSPSDAGLLPGAAVAVEGRRVAWVGRDRDLEAEVNAGGAQVIDARGGLVTPGLVDSHTHLVFAGERAGEFALRCAGRSYLQVALSGGGIAVTTRATRAAPDEQLLADAAARARRLIAQGVTTIEVKSGYGLDAPEELRLLRIVHQLGDALGGDATILPTLLFHAVPPEQVGDRAAFVREACAALIPQVARERLAVFCDVFVEDGAFAPDEARRLLQAAKDRGLVPRVHAEQLTAGGGARLAAELGCASADHLEELDDAGVAALAEARVVAGLLPLSTLFLGSERYAPARRLLEAGVPVSLATNMNPGSAMSENVGLTLSLACLKLGLTPAEALVAFTAGGARALRQPDLGRIARGADADLVLWGCGSPEHLAWHMAVNHALVVVKHGRVVHEAPSAAMVDCR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_DESVM
Sequence: MESKRAIIAIALSFVVLVGWSYLADHMGWNGQPAPQAQQEETAPSASQAAPQSASQAAAPAPRAETPVFLPSAGREVTVVTPLYKAVLHSGGGVLKHFSLTRYRTAITAGAPAVDMVDTASTVMSPLGLLINGQPSWNTGQWSFDGGDLSLGAGQSGVLTFTGEVDGVRVVRELTFSADTYLISEKVRLAPLADARTVRLGFTVGTGNLSPNGGQYDHTRVAWLHDGSFSEKTSASDLEKGVLETGALSWGAVMSNYFLVAAAPVDTTGVTLKGKLQEGVYRVAMERGDVSIPAGGETTVACNYWFGPKDRGLLKEAPNQLAEAINLGWFSIIARPLVDMLEFFHKYVGNYGVAIILLTVVIKLVFWPLSHKSYKSMEQMKKLQPMLQKLREKHGDDREKMNEEMMRLYKTYKVNPAGGCLPMLVQIPVFFGLYQALLNAIELRHASFITHLPFTDMVWLADLSAKDPYYITPIVMGATMLLQQKLTPAPGDPTQAKIMMFMPVVFTFMFLSFPSGLVVYWLCNNVLSIAQQWWMLRKA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_LACDA
Sequence: MSIDFKKYIASVKDFPNEGIIFRDITPILQDGEAFAAATHEIAEYAKSRQADVIVGPEARGFLVGTPVAIELGIGFVPARKPHKLPREVEAAAYDLEYGSNVLEMHKDAIKPGQRVVICDDLMATAGTMHATKELIERLGGKVVGAAFYIELTDLKGREKFPDVDIFSLVQYTGA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LANZ_LACLL
Sequence: MSTKDFNLDLVSVSKKDSGASPRITSISLCTPGCKTGALMGCNMKTATCNCSIHVSK
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
What are the official names of this protein?
Lantibiotic nisin-Z.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
Protein: ACKA_MESFL
Sequence: MILVVNAGSSSIKFRLFNDLDKSNPIDILDGLAERITVDGAVSFKYEGKKYEYNVELPNHEVAIKFILDKLIELNIISNVDDINAVGFRVVHGGTISKSSIIDQKVFDTIKDAVKLAPLHNPGAITAIEAIEKVMPKAKLVACFDTAYHQTLAEEQYLYAVPYSWYKEHGVRKYGFHGISYQYIAEKMSEVLAKPKDQLNLIVCHLGNGASITCIKNGKSFDTTMGLTPLAGVMMGTRSGDIDPSIIEYMCKELQLDVSKITNILNKESGLLGLSGKSSDMRDVTGGYFKGDEDYKRALNKYTQVSADYIIRFANLLGHNIDGIVFTAGVGENSIHTRQFILEKLPLLDIEIDNAKNEESYGDYKYISSPNSKIKVLAVRTNEELMICKDTINLTK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_SHESA
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQSEKSGTPSEGGNF
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_LITCT
Sequence: MKAIAVLKGXSEVTGVVRFEQQED
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_OCEIH
Sequence: MLAKRIIPCLDVDNGRVVKGKKFLDIQDVADPVELAKRYNDEGADELVFYDITASNEQRGIFLDVVEKVAKEIAIPFMVGGGIRTTKDIHQVLRSGADKVSINSAAVQRPELIFESAQKFGSQCTVLSIDAKEIAVGKWNVFINGGRKDTGIDAIEWAKKGESYGAGEIVVNAMDADGEKNGYNLPLTTAIATAVNIPVIASGGAGNIQHFKDVLSHEIDAALAASVFHYDEIKIPALKTYLNEQEISVRRNSK
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.