PharMolix/UniProtQA huggingface dataset:
Protein: TREH_THEAC
Sequence: MLVAMNGFIDWGCLPNFNSPAVFSSILDKKKGGYFAIYPTDTHDLYVDQYYKELTNILVTEFIKNGKVILRTTDFMPDSEYGKISFPEVHRFVETFSDPVRITIDFKPAFNYATERPLIQRVQHGFIFSTEKENMGISTEFQLKKNADHVFADVDMEPRSSSWVIALYGIHHLYRPTDYKSYLRLQETTDYWRKWASNSTYSGMYHSMVMRSALALKVLFYEPTGMMVAAPTASLPEAIGGERNWDYRYTWIRDTAYVIEALATIGYKREAVSFLYDMMDVISRENKIRTIYSIDNSDDFVERELDFEGYRGSRPVRIGNKAVDQLQIDQYGSIVRAIHAMEKAGGVVNSYLWDFVEEMMAKIEYLWKYPDSSIWEFRTEPKQYVYSKVMSWAAFDSAITMARDLGLTAPIKKWKGIQDEIWNDVMTKGFDPQTNSFVQYYGSKNVDASLLRLPILGFIPANDERFIGTMKRIEDELMVDGYLFRRYREDDGLKGDEGSFLMLTFWYIEDLILMKRLKAARAALESIIEKANHLGLYSEEIDEKTGDFLGNFPQALSHLGIIRVAPKLEEAFLKRVSKINE
What is the function of this protein?
Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose.
What are the official names of this protein?
Trehalase, Alpha,alpha-trehalase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 15 family.
Protein: TRIM6_MOUSE
Sequence: MTSTVLVDIRDEVTCPICLELLTEPLSIDCGHSFCQVCIIGNSNNSVFGQGGRSSCPVCRTSYQPGNLRPNRHLAAIVKRLREVALCPGKQLEVIFCALHGEKLQLFCKEDGKLICWLCERSQEHRGHHTFLMEEVAQEYQDMFQESLKKLRREQQEAEKLKALIQEKRESWKSQVEPEKRRIQTEFKQLRSILDREEQRELKKLEVEERKGLSIIEKAEGDLIHQSQSLKDLISDLEHRCQGSTVELLQDVGDVTKRSEFWTLRKPQALPTKLKSLFRAPDLRKMLKVFRELTDVQSYWVDVTLNPQTANLNLVLSKNRRQVRFVGAQLSEPSSLEEHYDCSVLGSQHFSSGKYYWEVDVSKKTAWILGVCSTPVDPMFSFSQYSSKQGAYSRYQPQCGYWVIGLQCKHEYRAYEDSSPSLLLSMTVPPRRIGIFLDCEAGTVSFYNVTNHGLPIYTFSKYYFPSALCPYFNPCSCIVPMTLRRPTS
What is the function of this protein?
E3 ubiquitin ligase that plays a crucial role in the activation of the IKBKE-dependent branch of the type I interferon signaling pathway (PubMed:24882218).  In concert with the ubiquitin-conjugating E2 enzyme UBE2K, synthesizes unanchored 'Lys-48'-linked polyubiquitin chains that promote the oligomerization and autophosphorylation of IKBKE leading to stimulation of an antiviral response (PubMed:24882218).  Ubiquitinates also MYC and inhibits its transcription activation activity, maintaining the pluripotency of embryonic stem cells (PubMed:22328504).  Promotes the association of unanchored 'Lys-48'-polyubiquitin chains with DHX16 leading to enhancement of RIGI-mediated innate antiviral immune response (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 6, RING-type E3 ubiquitin transferase TRIM6.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_STAAE
Sequence: MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELLEGARDGKTVAELMSYGRQILNKEDVMDGVEHMITDIEIEATFPDGTKLITVHHPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNCB_SHIDS
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLRKFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPSKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: RS6_LEIXX
Sequence: MHQYELMVILDPEIDERTVAPSLDKFLNVVRNDGGTIDNVDIWGRRRLAYEINKKSEGIYAVVQLTATGDTTKELDRQLKLSEAVMRTKVLRADEAIAQVAAAQKRADEKAARKAAAAEKTVTEKVGV
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ECM13_YEAST
Sequence: MNSTTPSIQDQYILASKVRSKLAKCVSVTTKNKDYNLRVLVGHANLLDKITENVETHNAATNALAGDPFSKGPENLSIEHIELSNANASKNDVGKEENAEKTIESEDYCDFYSSDEDPDADTLSSTDSEDDDDYEDYDFEYDYSGGDYNKKIDMYFSFHTAPNYQYLTHTNSHSEQTDELAESTPRYNALPATASTTEEEQDTETLDAVSLHSSAPIFRVLSRRVNGQEDDSENESSSDVDDGSVPLTRFHSCPITA
What is the function of this protein?
May be involved in cell wall organization and biogenesis.
What are the official names of this protein?
Protein ECM13, Extracellular mutant protein 13.
Protein: TAL_PICTO
Sequence: MKIFLDTANIDEIKDAIEYGLIDGVTTNPTLISREQKEGRGFSDIVKDILKTVDGPVSIEVVATDYQGMIDQATKIHNLGPNAVIKIPMTLAGLRAMKTLSEKHIPVNCTLVFNAIQATLAARNGAEYVSPFVGRLDDIGEDGMEIINQIRTIYNNYSFKTKILVASVRNPVHVLRSMIIGADVITMPYDVIKKLAMHPKTDEGLSKFLSDWKKVSPDGSFPI
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RKM5_CANGA
Sequence: MPFSLVRIDEDDVLEYVFERYTAINSDADSIRQDLGIQDSKSTTLNIEIAPPKSLINDTNITKKGKKKKGNKSSSDYDFYSFEIKQNVTSLHSTRDNDNSTTGYVLWSLTPVFCEWLLYNEQASPLHRAQMVNICSLEKKIIHDIEFPSLLNEDTTVIELGSGISSVLPILCSNFVGTYICTDQRGILNGLKQNIANNLDLVNKRTIVSETLDISNIQEQPTNSDDETIPIKPTTQLEVAILDWETFPKSIKSGSSNILTDFVKPHGTIFLLALDVIYNEYLINPFLHTLHSIMFYYKNQREIVALVGIHLRSDDIVQEFLEKVTTEFPFKLHVVDDPQWSHSRYDIYYITL
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates 60S ribosomal protein L1.
What are the official names of this protein?
Ribosomal lysine N-methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RKM5 family.
Protein: ZAPD_JANMA
Sequence: MIVYEYPFNERIRTLLRLEDLYEKFAFFIGQDHPQHHHVALATMFEMLEVAGRADLKSDLLQELERQKQTLLGFKSNPNVEAEMLDAILFDLDRISAALIASQGKTGQHIRENEWLMSIRGRTIIPGGACEFDLPSYYAWQHDSAEQRLADIHKWFTPLAPLFDAIGMVLRLLRESGRPVKMIAQTGSYQQMLQGKAYQMLRLNIDEALGAIPEISANKYMLWIRFTSQDGDMKPKAFEGDVPFELSLCSF
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: HTPX_SALCH
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLLIMALLFGFGGSFISLLMSKWMALKSVGGEVIEQPRNERERWLMNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRIIAQIAAGFLGGNRDEGEGSNGNPLIYFAVATVLELVFGILASIITMWFSRYREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRSGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH10_CHLP8
Sequence: MNLKPLADRVIVKPAPAEEKTKGGLYIPDTGKEKPQYGEVVAVGEGKVADNGQLVQMQVKVGDKVLYGKYSGTEVQVEAEDYLIMRESDIFAILG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPM_BREBN
Sequence: MEQWRYIVTEAMSPAMNMAVDEAILQLHSEGKVPPTVRFYTWDPATLSIGYFQKAIKEINLEEVQNRGLGFVRRATGGRAVLHDQELTYSVIVSEDHPKMPSSVTEAYKIISLGLLHGFQNLGLSAEMVSLASEEEKEKYNSPGSSACFDSPSWYELVVEGKKVAGSAQTRQKGVILQHGSILLDMDVDLLFSLLHFPSERVKQRMIDSFRQKAVTINEVSSRPISLQESIEAFSKGFASGLEVELTPSTLTDEELALAEELVRTRYATDEWNLRR
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.
What are the official names of this protein?
Octanoyltransferase LipM, Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipM family.
Protein: RSMG_SULNB
Sequence: MQYLNAEGIVLDDGIIGKLEGFAVLLHEWNQVHNLTGARSVVAIYDNIVDSLYPLTFIRIPKTLLDVGTGAGFPGLVLAIALPETEVVLAEPLKKRVSFLKYAAIDLGLKNVTVEAKRVENVVYEAFDMISSRAVTNTKLLLDLTSRISDEHTEYLFYKGSRVFDEIAQVEGQMSYDIIQKNQRNYLYIKNET
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADA_SULIN
Sequence: MSNEVEQKKSIKTINDLPGISQTVINKLIEAGYSSLETLAVASPQDLSVAAGIPLSTAQKIIKEARDALDIRFKTALEVKKERMNVKKISTGSQALDGLLAGGIETRTMTEFFGEFGSGKTQLCHQLSVNVQLPPEKGGLSGKAVYIDTEGTFRWERIENMAKALGLDIDNVMNNIYYIRAINTDHQIAIVDDLQELVSKDPSIKLIVVDSVTSHFRAEYPGRENLAVRQQKLNKHLHQLTRLAEVYDIAVIITNQVMARPDMFYGDPTVAVGGHTLYHVPGIRIQLKKSRGNRRIARVVDAPHLPEGEVVFALTEEGIRDAEE
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: SYT17_PONAB
Sequence: MAYIQLEPLNEGFLSRISDLLLCRWTCRHCCQKCYESSCCQSSEDEVEILGPFPAQTPPWLMASRSSDKDGDSVHTASEVPLTPRTNSPDGRRSSSDTSKSTYSLTRRISSLESRRPSSPLIDIKPIEFGVLSAKKEPIQPSVLRRTYTPDDYFRKFEPHLYSLDPNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLVKGGHWWKALIPSSQNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSESNHWRRMLNTHRTAVEQWHSLRSRAECDRVSPASLEVT
What is the function of this protein?
Plays a role in dendrite formation by melanocytes.
What are the official names of this protein?
Synaptotagmin-17, Synaptotagmin XVII, SytXVII.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: F16PC_STAAT
Sequence: MTQITEKELKKKYLDLLSQNFDTPEKLATEIINLESILELPKGTEHFVSDLHGEYEAFQHVLRNGSGNVRAKINDIFKERLSTKELNDLTALVYYPEDKLKLIKSDFQNCGQLNVWYITTIEHLIELIKYCSSKYTRSKLRKALPKQYVYIIEELLYKSNEYQNKKSYYETLVNQVIELKQADDLIIGLAYSVQRLVVDHLHVVGDIYDRGPQPDKIMDTLINYHSLDIQWGNHDVLWVGAYAGSKVCLANLLRICARYDNLDIIEDAYGINLRPLLTLAEKYYDADNPAFKPKKRPDKHERLTQREESQITKIHQAIAMIQFKLEIPIIKRRPNFEMEERLVLEKVNYDTNEITVYGNTYPLKDTCFQTVNRDNPAELLPEEEEVMNKLLLSFQQSEKLRRHMSFLMRKGSLYLPYNGNLLIHGCIPVDENGEMESFEIDGHTYSGQELLDVFEYHVRKSFDEKENTDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIADKASHKEEKNPYYHLREDVNMVRKMLSDFGLNPDEGRIINGHTPVKEINGEDPIKADGKMLVIDGGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQQFNAKEKILSEGIDELSIKRVVDKELQRKKIRDTNIGKDLQAQIDILKMLMHDRYLD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: Z36L3_MOUSE
Sequence: MANNNLNRPLNTNVADSSNSSSTPGTAPPPSSSDPQVLGHQAPSSSASSLTEDCSSSFARDLNSYNNGQSGATGAVSWEAPHEPSEANAVSQIHPRNGEHSLQQKPKPQKVSGSSSLATSERYKTELCRPFEESGICKYGHKCQFAHGYRELRTLSRHPKYKTEPCRTFHSVGFCPYGTRCHFIHNQPEQQPVLSESTLEEPSSFNGSNVLHLGVNGEQQPGLQSDSPSGFLSVNSQALQAPLQLNQQALSSGGVMPSSHPAAANLRMMCCRTSSSTTAHDADKDPDKDADKDPSNNSANDALAFPQEPGDFSPVAFQNPNTATTTPTAFYNNQQQMGLAASAQFQMPLARPLPSATIFGQASVGPALTPGAAMAPGAALAPAAALTPAAALAPGAAMALGAAMATGAAMATGAALTPGAALALGAAMAAGAALAPGAAMAPGAAMATGAALAFGAAMATGTTLTPGAAMALGAAMATGAALAPGAAVAPRAALAPRAAFAPGAAALAPRAALPPGAALTPGAALAPGAALAPRAALPPGATLRPGAALIPRAALAPGAALAPGAALTPGAALAPGATLAPRAALAPGAALAPRITITSRAAITPGVAIAPGVATASTGILAPGAATATVGNTSSTTITAATAAEGAAPHFTFQLPDVESESESESLEFDVVTSTLDSLLVSDDEDEDDFLRRSSSSSSLNESEFDNTNSSRRLPIFSRFSDSEK
What is the function of this protein?
Placenta-specific zinc-finger RNA-binding protein that destabilizes cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis (PubMed:15814898, PubMed:26952984).  Binds to the 3'-UTR ARE of placental target mRNAs, such as TNF, HBEGF and LIPG (PubMed:15814898, PubMed:18367448, PubMed:26952984).  Involved in placental expression of many genes important for normal placental physiology (PubMed:26952984).
What are the official names of this protein?
mRNA decay activator protein ZFP36L3, Zinc finger protein 36, C3H1 type-like 3, zinc finger protein 36-like 3.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Multi-pass membrane protein. Note=Localizes exlusively in the cytoplasm (PubMed:18367448, PubMed:15814898). Not detected in the nucleus despite the presence of a nuclear localization signal (NLS) in the zinc finger regions; a C- terminal alanine-rich repeat domain is able to override the activity of the nuclear localization signal and prevent import into the nucleus (PubMed:18367448, PubMed:26493225).
Protein: DCS3_GOSAR
Sequence: MASQASQVLASPHPAISSENRPKADFHPGIWGDMFIICPDTDIDAATELQYEELKAQVRKMIMEPVDDSNQKLPFIDAVQRLGVSYHFEKEIEDELENIYRDTNNNDADTDLYTTALRFRLLREHGFDISCDAFNKFKDEAGNFKASLTSDVQGLLELYEASYMRVHGEDILDEAISFTTAQLTLALPTLHHPLSEQVGHALKQSIRRGLPRVEARNFISIYQDLESHNKSLLQFAKIDFNLLQLLHRKELSEICRWWKDLDFTRKLPFARDRVVEGYFWIMGVYFEPQYSLGRKMLTKVIAMASIVDDTYDSYATYDELIPYTNAIERWDIKCMNQLPNYMKISYKALLNVYEEMEQLLANQGRQYRVEYAKKAMIRLVQAYLLEAKWTHQNYKPTFEEFRDNALPTSGYAMLAITAFVGMGEVITPETFKWAASDPKIIKASTIICRFMDDIAEHKFNHRREDDCSAIECYMKQYGVTAQEAYNEFNKHIESSWKDVNEEFLKPTEMPTPVLCRSLNLARVMDVLYREGDGYTHVGKAAKGGITSLLIDPIQI
What is the function of this protein?
Responsible for the cyclization of trans,trans-farnesyl diphosphate (FPP) to (+)-delta cadinene.
What are the official names of this protein?
(+)-delta-cadinene synthase isozyme A, D-cadinene synthase A.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: RK16_ATRBE
Sequence: MLSPKRTRFRKQHRGRMKGISYRGNHISFGKYALQALEPAWITSRQIEAGRRAMTRNARRGGKIWVRIFPDKPVTLRPAETRMGSGKGSPEYWVAVVKPGRILYEMGGVTENIARRAISLAASKMPIRTQFIIS
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UREF_RHOPS
Sequence: MSTSRAPETTSAAPLSAEQSASLYRLMTWLSPAFPVGAFSYSSGLEWAVEAGDVIDAPSLRDWLTAMLEHGAGFCDGVFLAHAYRAVAAADETALRHVAELATAFVPSAERHLETTAQGKAFIEIVRNAWPSDGLACAVDACAGALAYPVAVGLVSATHGVPLAATLHAFLHAVVSNWISAGARLVPLGQTDSQRVLAALEPAVIAAGDRAREASLDDLGSATFRADLASLRHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP2_METCA
Sequence: MPIVIEQSARGERAFDIYSRLLKERVIFLVGQVEDYMANLVIAQLLFLESENPDKDIHLYINSPGGLVTAGLAIYDTMQFIKPDVSTLCVGQAASMGALLLAGGAAGKRYCLPHSRIMIHQPLGGFQGQASDIDIHAREILAVRDRLNKILAHHTGQPIEKIQIDTDRDNFMGGDDAVSYGLIDKVLTHRTVTAA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX2F_CENTE
Sequence: IFINVKCSSPQQCLKPCKKAFGQHAGGKCINGKCKCYP
What is the function of this protein?
Blocks human voltage-gated potassium channels Kv1. 2/KCNA2 (IC(50)=0. 3 nM), Kv1. 3/KCNA3 (IC(50)=8. 3 nM) and Shaker IR (with inactivation domain removed) (IC(50)=12 nM) and blocks intermediate conductance calcium-activated potassium channel KCa3. 1/KCNN4 (IC(50)=6. 4 nM).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 2.15, Toxin II.10.5.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 02 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OMP5_GLAPU
Sequence: APQANSFYVGAKAGD
What is the function of this protein?
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm.  Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.
What are the official names of this protein?
Outer membrane protein P5, OMP P5, Outer membrane protein A.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RL24_CERS1
Sequence: MAAKLKKGDRVVVLAGKDKGKQGEITAVMPKDNKAVVEGVNVAIRHTKQTPTAQGGRLAKAMPIDLSNLALLDANGKATRVGFRFEGEKKVRYAKTTGDVI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HLDD_ACTSZ
Sequence: MIIVTGGAGFIGSNIVKSLNDLGRKDILVVDNLKDGTKFINLVDLDIADYCDKEDFIAQIIAGDDFGDIDAVFHEGACSATTEWDGKYIMHNNYEYSKELLHYCLDREIPFFYASSAATYGDKTEFVEERQFEGPLNVYGYSKFLFDQYVREILPNASSPVCGFKYFNVYGPREQHKGSMSSVAFHLNNQILKGENPKLFAGSEHFLRDFVYVGDVAAVNIWAWQNKISGIFNCGTGHAESFKAVAEAVIKHHGKGAIETIPFPDHLKSRYQEYTQADLTKLRAAGCNLKFKSVAEGVAEYMAWLNRK
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: LEUC_PROM1
Sequence: MSSRTLYDKVWNFHQVKELPGGSTQLFIGLHLIHEVTSPQAFSALNEKKLGVKFPNLTVATVDHIVPTSNQQRPFSDPLAEEMLSTLEKNCKTHGIKFHGIGSNSQGVVHVMAPELGLTQPGMTVACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQSLAMNKLKVRRIWVEGELQKGVYAKDLILHIIRHLGVKGGVGFAYEFAGPAIEKLSMEGRMTICNMAIEGGARCGYINPDETTFKYLKGKEHAPKGQEWDKAISWWKSLASDSKATFDDEIQLDGSSIEPTVTWGITPGQGISIKETIPNPEFLPKNEQQIAKDACKYMNLKPDEPIEGQSIDVCFIGSCTNGRLSDLQEASKIVKGNTVADGIRAFVVPGSQKVAKEAKEKGLDKIFLKAGFEWREPGCSMCLAMNPDKLEGRQISASSSNRNFKGRQGSAKGRTLLMSPAMVAAAAINGRVTDVRKFLQE
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: BIOB_SHEFN
Sequence: MSLAEVRHDWQKAQIEALFALPMNDLLFKAHSIHRETFDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLLEIDKVLTEAKSAKAAGASRFCMGAAWRNPRDKDMPYLTQMVKDVRALGMETCMTLGMLSSEQAGKLADAGLDYYNHNLDTSPEYYGDVITTRTYQSRLDTLTNVRASGMKVCSGGIVGMGEKATDRAGLLQQLANLEQHPDSVPINMLVKVAGTPFENIDDLDPLEFVRTIAVARILMPKSRVRLSAGRESMSDELQSMCFFAGANSIFYGCKLLTTPNPEENDDMSLFRRLGLHPEQGPQANIENDSALLAKASAKQDKSTKQFFDAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: KV02_RABIT
Sequence: AQIVMTQTPSSVSAAVGGTVTINCQSSQSVYENGRLSWFQQKPGQPPKRLIYRASTLASGVSSRFTGSGSGTQFTLSISDVQCDDAATYYCLGNYDCSSGDSFTFGGGTEVVVKG
What are the official names of this protein?
Ig kappa chain V region 3315.
Protein: ISPF_SYNWW
Sequence: MRVGYGYDVHRLQEGRRLVLGGVEIPHMQGLLGHSDADVLLHAICDALLGAAALGDIGQHFPDSDSQYKDINSLLLLKEVAGILQRAGWRVINVDSTVVAQEPRLAPHIKQMRQNIARVLAIESEQVSVKATTTEGLGFAGRQQGISAHAVVLIEQA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: Y1099_LACGA
Sequence: MTDQLLVTTTENIPNQKYEIIGEVFGVTTQSKNALRDLGAGLKSIVGGEIKAYTSMLTESRDQAINRLCENAANLGADAVVMMRFDSGSIAGDMQSVVAYGTAVKFID
What are the official names of this protein?
UPF0145 protein LGAS_1099.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PYRD_RALSO
Sequence: MLNALYPLARPLLFSMDPEDAHHFTLNQLKRAHALGLSGCIGARVAPQPRTVMGIAFPNPVGLAAGLDKDGAYIDALGALGFGFIEVGTVTPRAQPGNPRPRMFRLPAASALINRMGFNNGGVDAFIRNVQASKWREAGGVLGLNIGKNADTPIERAVDDYLHCLERVYPYASYVTVNISSPNTKNLRQLQGASELDSLLGTLRGAQQRLADQHKRYVPVVLKIAPDLDDDQIANIGDALLRHRMDGVIATNTTIRREAVAGLPHAEEAGGLSGQPVREGSTRVIRALCGLLGDAVPIIGVGGILAGEHAREKIDAGAQLVQLYTGLIYRGPGLVAECARALAR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEF2_NPVOP
Sequence: MERVWNPAAGIDGLKRSETYLVDPHDFVGVLTLSPYTVFERGLFVRMSGMRLLALLAAPKPQEPQPAVRRFPQRSRRNVCLKACADGAQSLAKVLAARVSMPPCMSKTMADLSSAPRGNMYRKRFEFNCYLANVITCTKCKTACLIGALLHFYRMDAKCVGEVTHLLIKAQDVYKPSNCAKMKKVTKLCPQASMCKGLNPICNF
What is the function of this protein?
Required for late and very late gene expression.  Specifically required for expression from the vp39 and polh promoters (By similarity).
What are the official names of this protein?
Late expression factor 2.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-2 family.