PharMolix/UniProtQA huggingface dataset:
Protein: TBB4A_BOVIN
Sequence: MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEEEVA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
What are the official names of this protein?
Tubulin beta-4A chain, Tubulin beta-4 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CR9DA_BACTP
Sequence: MNRNNQNEYEVIDAPHCGCPADDVVKYPLTDDPNAGLQNMNYKEYLQTYGGDYTDPLINPNLSVSGKDVIQVGINIVGRLLSFFGFPFSSQWVTVYTYLLNSLWPDDENSVWDAFMERVEELIDQKISEAVKGRALDDLTGLQYNYNLYVEALDEWLNRPNGARASLVSQRFNILDSLFTQFMPSFGSGPGSQNYATILLPVYAQAANLHLLLLKDADIYGARWGLNQTQIDQFHSRQQSLTQTYTNHCVTAYNDGLAELRGTTAESWFKYNQYRREMTLTAMDLVALFPYYNLRQYPDGTNPQLTREVYTDPIAFDPLEQPTTQLCRSWYINPAFRNHLNFSVLENSLIRPPHLFERLSNLQILVNYQTNGSAWRGSRVRYHYLHSSIIQEKSYGLLSDPVGANINVQNNDIYQIISQVSNFASPVGSSYSVWDTNFYLSSGQVSGISGYTQQGIPAVCLQQRNSTDELPSLNPEGDIIRNYSHRLSHITQYRFQATQSGSPSTVSANLPTCVWTHRDVDLDNTITANQITQLPLVKAYELSSGATVVKGPGFTGGDVIRRTNTGGFGAIRVSVTGPLTQRYRIRFRYASTIDFDFFVTRGGTTINNFRFTRTMNRGQESRYESYRTVEFTTPFNFTQSQDIIRTSIQGLSGNGEVYLDRIEIIPVNPAREAEEDLEAAKKAARQNLFTRTRDGLQVNVTDYQVDQAANLVSCLSDEQYGHDKKMLLEAVRAAKRLSRERNLLQDPDFNTINSTEENGWKASNGVTISEGGPFFKGRALQLASARENYPTYIYQKVDASVLKPYTRYRLDGFVKSSQDLEIDLIHYHKVHLVKNVPDNLVSDTYSDGSCSGMNRCEEQQMVNAQLETEHHHPMDCCEAAQTHEFSSYINTGDLNASVDQGIWVVLKVRTTDGYATLGNLELVEVGPLSGESLEREQRDNAKWNAELGRKRAEIDRVYLAAKQAINHLFVDYQDQQLNPEIGLAEINEASNLVESISGVYSDTLLQIPGINYEIYTELSDRLQQASYLYTSRNAVQNGDFNSGLDSWNTTTDASVQQDGNMHFLVLSHWDAQVSQQLRVNPNCKYVLRVTARKVGGGDGYVTIRDGAHHQETLTFNACDYDVNGTYVNDNSYITEEVVFYPETKHMWVEVSESEGSFYIDSIEFIETQE
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.
What are the official names of this protein?
Pesticidal crystal protein Cry9Da, 132 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIXD(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: PSB1_DANRE
Sequence: MISAQAYGENGKMKEYHYTGPVEHKFSPYAFNGGTVLAVAGEDFAIVASDTRLSEGYSIHSRDSPKCYKLTDTTVLGCSGFHGDCLTLTKIIEARLKMYKHSNNKSMTSGAIAAMLSTILYGRRFFPYYVYNIIGGLDEEGRGAVYSFDPVGSYQRDTYKAGGSASAMLQPLLDNQIGFKNMENVEHVPLTQEKAVQLVKDVFISAAERDVYTGDALKVCIVSKEGIKEEIVPLRKD
What is the function of this protein?
Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.
What are the official names of this protein?
Proteasome subunit beta type-1, Proteasome beta-subunit C5.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
Protein: TVB9_HUMAN
Sequence: MGFRLLCCVAFCLLGAGPVDSGVTQTPKHLITATGQRVTLRCSPRSGDLSVYWYQQSLDQGLQFLIHYYNGEERAKGNILERFSAQQFPDLHSELNLSSLELGDSALYFCASSV
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta variable 9.
What are the subcellular locations of this protein?
Cell membrane.
Protein: LGT_CHLAD
Sequence: MVLYPPDDPFLISFTLFGLPIVVRWYGAIIMTGALIAALLASRRAVARGYHPDHVWNQLMLGLVLGIAGARIYYVAFEWERFAPNPWSVFNLTTGGIAIHGAIIGALLSTVIYTRYAGLPYWDWLDVCVPGFLLAQSIGRWGNFFNQEAYGRPTDLPFGLRIDPEYRVPPYNDLTTYPITTLFHPTFLYESVWNLVGVGILLWLDRRFGRLAPPERRRLNPGDLLFLYGIIYSSGRFWIEGLRIDSLCANGVGGSCEGSIRVAQLVSMVAIVVCGVLIFLNHRRPFAGTPTVRPDGDASPVSEAR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS12_EHRCR
Sequence: MPTINQLVRKPRKSRSSLNKAPALQHNPQKRAVCVKVYTTTPKKPNSALRKVARVKIAGYGSEVIAYIPGEGHNLQEHSVILIRGGRVKDLPGVRYHIIRGALDSRGVQNRKKARSKYGVKKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MTGA_NEIMA
Sequence: MFRIIKWLIALPVGIFIFFNAYVYGNIITYRAVAPHRTAFMSMRMKQFEQEGRDVALDYRWMPYKRISTNLKKALIASEDARFAGHGGFDWGGIQNAIRRNRNSGKVKAGGSTISQQLAKNLFLNESRSYIRKGEEAAITAMMEAVTDKDRIFELYLNSIEWHYGVFGAEAASRYFYQIPAAKLTKQQAAKLTARVPAPLYYADHPKSKRLRNKTNIVLRRMGSAELPESDTD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GM_HHV7J
Sequence: MALSRVDVINMRIWVLSIICACLTYVNVTVHLVAVHFPNLGFPCAYYEINDMKAINLSIRNDIRSLTPQLYLNPIQLICYVVFMDICFFFILVYYIVCCVKVFSSEKTPNINQSTRDITWMGDSLSCFQFVLTMDTYQFFVTCLSFRLVTLAAFTYCLFFICFTAFTLTMITQYQSSERSFFVLKRIHPKLKGTIKYKTIIINMIELMLGFSSMVFAITICLGLGNNFYIKSSTVAFASINTFFVMSFVYSLVIELILHQYVKVQFGLHFGILFGILGLTYPILKYDSLFKTEWTVKFIVNLAVITIVCLSFIICRLIRFFMRKHHNYKKLPTTVEDLDVLEEANE
What is the function of this protein?
Envelope glycoprotein important for virion assembly and egress.  Plays a role in the correct incorporation of gH-gL into virion membrane.  Directs the glycoprotein N (gN) to the host trans-Golgi network.
What are the official names of this protein?
Envelope glycoprotein M, gM.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein M family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein accumulates in the trans-Golgi network where secondary envelopment occurs.
Protein: PNP_ANADE
Sequence: MTPIQKTATVGGKEVLLETGKVAKQAHGSVWVRLGDSIVLVTAVSAAEKKEGIDFFPLTVDYQEKLFAAGRVPGSFFRREGRPTEKETLTSRLVDRSCRPLFAEGYSNETQVIATVISFDQENDTDVLALTGASAALHISDIPFGGPIAGVRVARVGGQLVANPTLAQRADADLDVVMAASRDAIVMVEGGAQEVSEAVMIEALLFGQAAVQPLLDAQDALRAATGNKPRRAFDPPKNDVELRAKVKALTWEKVKEAYGRDEKHDRYGRLSEIKKELLQALKEEAAGDAAKLATIALREKEIKGYYEDVKYDYMRKMITDERRRIGGRGMADIRKITCEVGLLPRVHGSSLFTRGETQALVATTLGTAEDEQRVEMLTGMVFKKFMLHYNFPPFSVGEVKFLRSPGRREIGHGALAERALRAVMPPEDQFPYTVRVVSDIMESNGSSSMASVCGGCLSLMDAGVPIKAPVAGIAMGLIKEGEKIAILSDILGDEDHLGDMDFKVCGTAAGITSIQMDIKIGGVTREILEQALSQAAEGRKHILGEMAKALSAPRGSISAYAPRITTIKIRPERIKDIIGPGGKTIKDITARTGTSINIEDDGSVSIASPNQDKVEEAIKMIRGLTQEAEVGRIYMGTVRKIAEFGAFVEIFPGTDGLIHISELSDKRVKSVSDVLSEGEEVMVKVISVDRSGKIRLSRKEALADSAKKSEGTEPPKGEPAK
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_STAA2
Sequence: MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AG43_ECOLI
Sequence: MKRHLNTCYRLVWNHMTGAFVVASELARARGKRGGVAVALSLAAVTSLPVLAADIVVHPGETVNGGTLANHDNQIVFGTTNGMTISTGLEYGPDNEANTGGQWVQDGGTANKTTVTSGGLQRVNPGGSVSDTVISAGGGQSLQGRAVNTTLNGGEQWMHEGAIATGTVINDKGWQVVKPGTVATDTVVNTGAEGGPDAENGDTGQFVRGDAVRTTINKNGRQIVRAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQIVKNGGVAGNTTVNQKGRLQVDAGGTATNVTLKQGGALVTSTAATVTGINRLGAFSVVEGKADNVVLENGGRLDVLTGHTATNTRVDDGGTLDVRNGGTATTVSMGNGGVLLADSGAAVSGTRSDGKAFSIGGGQADALMLEKGSSFTLNAGDTATDTTVNGGLFTARGGTLAGTTTLNNGAILTLSGKTVNNDTLTIREGDALLQGGSLTGNGSVEKSGSGTLTVSNTTLTQKAVNLNEGTLTLNDSTVTTDVIAQRGTALKLTGSTVLNGAIDPTNVTLASGATWNIPDNATVQSVVDDLSHAGQIHFTSTRTGKFVPATLKVKNLNGQNGTISLRVRPDMAQNNADRLVIDGGRATGKTILNLVNAGNSASGLATSGKGIQVVEAINGATTEEGAFVQGNRLQAGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRIVAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLMRTEVAGMSVTAGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGKDNAGYVKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRAPLRDSAKHSVSELPVNWWVQPSVIRTFSSRGDMRVGTSTAGSGMTFSPSQNGTSLDLQAGLEARVRENITLGVQAGYAHSVSGSSAEGYNGQATLNVTF
What is the function of this protein?
Controls colony form variation and autoaggregation.  May function as an adhesin.
What are the official names of this protein?
Antigen 43, AG43, Fluffing protein.
What are the subcellular locations of this protein?
[Antigen 43]: Periplasm. SUBCELLULAR LOCATION: [Antigen 43 alpha chain]: Secreted. Cell surface. Note=The cell surface component is about 60 kDa and can be released by mild heat treatment (PubMed:22466966). SUBCELLULAR LOCATION: [Antigen 43 beta chain]: Cell outer membrane; Multi-pass membrane protein. Note=May form a beta-barrel.
Protein: COBQ_MARMS
Sequence: MPAFSLMIQGTTSDAGKSTLVTALCRLFYRRGISVAPFKPQNMALNSAVTKDGNEIGRAQAVQAYAAGLEPQVDMNPILLKPNTDTGAQVIIQGKAVGNMNAVGYHEYKSIAKVAALDSYQRLANQYQAVLIEGAGSPAEINLRARDIANMGFAESIDCPVIIIADIDKGGVFAHLVGTLDLLSPSEQDRVIGFVINRFRGDISLLQSGLDWLEERTGKPVLGVLPFLKGFHLESEDAVAKSPIKADSKAKLNIVIPIMPRTSNHTDWDALRLHPEVQVTLVGANETIPPADLVILPGSKSVQSDLAYLRQEGWEDYLNKHLRYGGKVIGICGGYQMLGEQLLDPLGLENQHANTRSTGFGFIPMETVLKEEKQLKQRQGQLAFAANAQVTGYEIHSGVSRFTDETQIAHFALLDDGKNKENSEKEGYISPDGQIIGTYLHGVFDHPDALQALLNWAGVDQAAAFDYDQFRDKEIDRLADSTEQNMNIDALIEQCQNFQQ
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: Y094_STAAN
Sequence: MKRLNTLVLYISFLILIISIVAGCGTGKEAEIKKSFEKTLSMYPIKNLEDLYDKEGYRDDEFDKNDKGTWTISSEMAIQKKGEALNIKGMVLKLNRNTRSAKGFYYVNAIKKDENGRPQDKQIEYPVKMIDNKIIPTKDIKDEKIKKEIENFKFFAQYGNFKDLTKYKGGDISYNPEAPIYSAKYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGSGNLDGSSIGYKKIEFTFVEKKGENTYFTANLHFKPSNDE
What are the official names of this protein?
Uncharacterized lipoprotein SA0094.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: Y149_MYCPN
Sequence: MAVGIFILSLNPSYELVDWKRVGDTKLVALVRSALVRVKFNDGTSSDSNNQDTNQNALSFDTQESQKALNGSQSGSSDTSGSNSQDFASYILIFQAAPRATWVFERKIKLELPYVKNESGAGDSTTTNSGSLYTTLQDLLVEQPVTPYTPNAGLARVNGAAQDTVHFGSGQESSWNSQRSQKVLKNNPGPKAVTGFKLDKGRAYRKLNEAWPVYEPLDSTKDGKGKDESSWNSSEKTTAESDAPLVGSTGSQMAAVTDSQQSGDNNGLVSLAQRSTTVAVQKSDSSGSQGQGTTDNKFQKYLNTTQALHQMGVIVPSLETWAGENKYWNRYPCCWWCFSPSSDPAIVFHKWRSTECNHPVIPYFNRPTRLLKWPDRCDGFERGTEFVVLGRGWANHVRKGYLMSPHRVELGHRQAEGVCGESAWFQWNQRHRLA
What are the official names of this protein?
Putative MgpC-like protein MPN_149.
What is the protein family that this protein belongs to?
Belongs to the MgpC family.
Protein: AGTA_DICDI
Sequence: MEKKVEYIKENDKIVLMCNYGFRDMTLNLLKCFEKLSIDKSRYILYCMDDKAYQFFAEFKGIECQRFSRDDIINSSTSSTQLFHDNNTNDNKGIYSENAESYGDIGFRAICNEKPLVVLDVLKKGYNVLWTDTDIVWKRDPFIHFYQDINQENQFTNDDDIDLYVQQDDDDICAGFYFIRSNQRTIKFIQDSINFLNPCIDDQIAMRLFLKSQGINIKSKNILLSLSENDKKDKIRYRLLDKKLFPNGTNYFNLKITQRDNITPFIIHNNCIIGHRSKKDRFIEYGLWYINDDEIDINSNINNDDENNKEIKLFKNVLKNHTDIITSINSSDDGKLFTTSIDKSIKIWKFENTSGNDTDNGIFKVLKSKYIHKRGGIWSTFIFSSNNNNNNDYGFENLLTSSHDKTIQYWDNNLQVIQTFIGHTGIINQLIVIPNSSYFFTCSDDNTIRQFDLNNINFKRVFIGHNGWVSSIAINKNLNTLYSCSNDGTIRFWDINSGRCLNIIKGNQGGWIRKIIYNDNLNQLISGGNDGTIKIWSCDNLNNFNDNQYLLKINTNENSSINDLQFDSDTNLIYCAFENGSLKSFKLTSNNNNNNNNNNNNNNNTINYSLDKVYQGHLNSSINCIHISKSLNLLFSGGFDKQIKSWDL
What is the function of this protein?
Specifically catalyzes the transfer of a galactosyl residue to the hydroxyproline-linked saccharide on Skp1 protein (fpaA/fpaB).  Catalyzes the formation of a Gal-alpha-1,3-Fuc linkage, leading to Gal-Fuc-Gal-GlcNAc-HyPro143-Skp1.
What are the official names of this protein?
UDP-galactose:fucoside alpha-3-galactosyltransferase, Alpha-GalT1, Fucosylgalactoside 3-alpha-galactosyltransferase, Skp1 alpha-3-galactosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 77 family.
Protein: DPH3_CRIGR
Sequence: MAVFHDEVEIEDFQYDEDSETYFYPCPCGDNFSITKEDLENGEDVATCPSCSLIIKVIYDKDQFMCGETVPAPSTNKELVKC
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase.  Acts as an electron donor to reduce the Fe-S cluster in DPH1-DPH2 keeping the [4Fe-4S] clusters in the active and reduced state.  Restores iron to DPH1-DPH2 iron-sulfur clusters which have degraded from [4Fe-4S] to [3Fe-4S] by donating an iron atom to reform [4Fe-4S] clusters, in a manner dependent on the presence of elongation factor 2 and SAM.  Associates with the elongator complex and is required for tRNA Wobble base modifications mediated by the elongator complex.  The elongator complex is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s 2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine).
What are the official names of this protein?
Diphthamide biosynthesis protein 3, CSL-type zinc finger-containing protein 2, Diphtheria toxin and Pseudomonas exotoxin A sensitivity-required protein 1.
What is the protein family that this protein belongs to?
Belongs to the DPH3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PPAC_STRT1
Sequence: MSKIFVFGHQNPDSDAIGSSYGYAYLKRQLGVEAEAVALGTPNEETAFVLDYFSVNAPRVVESAQSEGVNQVILTDHNEFQQSISDIKDVEVIEVVDHHRVANFETANPLMMRLEPVGSASSIVYRMFKENNVEIPKDVAGLLLSGLISDTLLLKSPTTHASDPAVAEELARLAGVNLEEYGLAMLKAGTNLSSKSAEELIDIDAKTFELNGNQVRVAQVNTVDISDVLSRQAEIEEAINSSIKSNGYSDFVLMITDILNSNSEILALGSNTDKIEKAFNFVLENNHAFLKGAVSRKKQVVPQLTESFNV
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX138_LYCSI
Sequence: MMKVLVVVALLVTLISYSSSEGIDDLEADELLSLTANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKILG
What are the official names of this protein?
U1-lycotoxin-Ls1v, Toxin-like structure LSTX-A38.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPIA_NEIMA
Sequence: MTTQDELKRIAAEKAVEFVPENEYIGIGTGSTINFFIEALGKSGKKIKGAVSTSKKSSELLAQYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHLNEKIVASASEKFVCIADESKYVSRLGKFPLPVEVVESARSLVSRKLLAMGGQPELRIGYTTFYGNQIVDVHGLNIDQPLTMEDEINKITGVLENGIFARDAADVLILGTEEGAKVIYPCQG
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: JZT48_CHIGU
Sequence: MRTFTLIAILTCAVLVIFHVSAAEELEAQDVIQPEDIFTGVATLEEDRIFECSFSCDIKKNGKPCTGAGEKKCSGGWRCKMNFCVKF
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Cg1c, U3-TRTX-Cg1c, Jingzhaotoxin-48, JZTX-48.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 03 (juruin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK_CLOBM
Sequence: MNYNKKSIEDIDVKSKKVLVRCDFNVPLNEGKITDENRLVGALPTVKYLMEKGAKIILCSHMGKPKGEPKKELSLLPVAKRLSEMLNKEVVFADDDNVVGENAKKAVEDMKDGDIVLLQNTRYRKEETKNEEIFSKELASLADVFVNDAFGTAHRAHCSTVGVTHYLKEAACGYLIQKELKFLGNAVETPERPFVAILGGAKVSDKINVINNLLDKVDTLIIGGGMGYTFLKSLGYTVGDSLLEEDKVEYAKEMINKAKEKGVNFLLPVDITIADRFDKDAEPIVTEDQNVKEGYMGLDIGSKTAKIYADAIKSAKTVIWNGPMGVFEFKNFANGTIEVAKAMADSDAVTIIGGGDSAAAVNIFGFGDKMSHISTGGGASLEFLEGKELPGIAALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_SACS2
Sequence: MIINSLKRFGITTGAAASAAAKAAVIGLLNKEKRSTVVIPTPIGLRLEIPVEKVEIDSEISCAEVKKFSGDNPDILDGLVIRCCAKLNENNEIVIIGERGVGKVTRSGLKATMGEMAISPTVREMIINAIREVTDKGIQITIEVPNGETIAEKTLNKMVGIVGGISILGTTGIETPVSDDDYLEHIRCELNVIRQSYDYVVIAPGNSAAKYAAELFDSNCIIKVGDRIGDSIKLASNLFKKVILAGLPAKLLKVYAGIFNTHYSQGDARLESLTHASVLAGLPYGTLTKISNALSVEEAFTYMTKEQRRKVMNIVAEKILSRIKSFNDNINFCVIIFDYDGESLSRVGC
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: ARR3_ARATH
Sequence: MAKDGGVSCLRRSEMIGIGIGELESPPLDSDQVHVLAVDDSLVDRIVIERLLRITSCKVTAVDSGWRALEFLGLDDDKAAVEFDRLKVDLIITDYCMPGMTGYELLKKIKESTSFKEVPVVIMSSENVMTRIDRCLEEGAEDFLLKPVKLADVKRLRSYLTRDVKVAAEGNKRKLTTPPPPPPLSATSSMESSDSTVESPLSMVDDEDSLTMSPESATSLVDSPMRSPGLA
What is the function of this protein?
Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Type-A response regulators seem to act as negative regulators of the cytokinin signaling.
What are the official names of this protein?
Two-component response regulator ARR3.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-A subfamily.
What are the subcellular locations of this protein?
Nucleus.