PharMolix/UniProtQA huggingface dataset:
Protein: TGT_FRATO
Sequence: MTVMKFDLIKKEGKARRGKITFPRGDIQTPAFMPVGTYGAVKSLSPVELKEMGAEIILGNTFHLWLRPGTEIIKKHGSLHGFNGWDKPILTDSGGFQVFSLGKMRKLTEEGVTFKSPVNSSKVFLSPEISMQVQRDLGSDIVMCFDECTPYPATEKEAKESMELSMRWAKRSKEAHGDNPSALFGIIQGGMYEHLRDESLAKLKEIDFDGFAIGGLSVGEPKEDMIRILDHTAHQMPEDKPRYLMGVGTPKDLVEAVYRGVDMFDCVMPSRNARNGHIFTSEGVIKIRNSKYKDDTSPLDPNCDCYTCKNFTKSYLHHLDKTKEILGSRLNTIHNLTFYQNLMKSIRKALDEGRFSEFRKEFLASYK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DSBD_SHIDS
Sequence: MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFTFDFQQNQHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTLPVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAAPQPVSVPQQEQPTAQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMALTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLTLMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYALGMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDIWGLRLWSALGVAFFGGAFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNFTQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQANVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_WOLSU
Sequence: MYAIVKNGGKQYKVQEGDIVLFDKMSLEPKSKVELNEVLALCKDDNLILGTPFVEGAKIEIEVINEDRAKKVVTFKKRRRKDSKTKRGFRRDFTRVRILKIAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ACSA_LEPIN
Sequence: MPNSEEVMAKERVVSPSAEFKKNANISLKNYKSLYKESIENPNKFWAREANRLIWFKKWTKVLSHDFKNAKVEWFKGGKLNVSYNCLDRHISTPLKNKAALIWEGDNPTESRVLTYYDVYREVNRFANILKKFGVKKGDRVLVYLPMIPELAITILACTRIGAIHSVVFGGFSPEALQSRIDDCKPKLVVTADGGFRGGKPIELKKNVDLALEKSKEKVKTVIVVRRTGNESGLTWKDGQDYWYHFLMNDPELSAYCKPEEMDAEDPLFILYTSGSTGKPKGVLHTTGGYLLGANLTFHYVFDIKPEDTYWCTADIGWVTGHSYLVYGPLSNGASSVMFEGVPSYPDAGRFWDVIDKYGVNIFYTAPTAIRALMREGLNHIQKRDLSSLRLLGSVGEPINPEAWEWYFKNIGKGKCPIVDTWWQTETGSIMITALPGAIPQKPGSATLPFFGVQPVLVDNDGKEITDKGEVSGNLCIKGPWPSMMRGVYGDPKRFFETYFSQFKGYYFTGDGARRDKDGYFWITGRVDDVINVSGHRIGSAEVESALVENKSVAEAAVVGFPHDIKGQGIYAYVTVKEGVTTNDVLKKELISTVEKMIGKIARPDVIHWAPGLPKTRSGKIMRRILRKIVSGEFEGLGDTSTLADPSVVQKLIEDKKKFHS
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PGK_ECO24
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BR1B_RANIT
Sequence: IVPFLLGMVPKLICLITKKC
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Brevinin-1ITb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: Y1857_STAS1
Sequence: MAKKAPDVGNYQYGFHDEDVSIFRSERGLTENIVREISNMKEEPEWMLNYRLKSLKQFYKMPMPQWGGDLSELDFDDITYYVKPSENTERSWDEVPEEIKRTFDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEDKGIIFKDTDSALRENEELFKQYFSTVVPAADNKFSALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLIIADEGASVNYVEGCTAPVYSTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRTLVYENGNMEWVDGNLGSKLTMKYPNCVLMGEGAKGSTLSIAFAGKGQVQDAGAKMIHKAPNTSSTIVSKSISKDGGKVVYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYNEVFNDNISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
What are the official names of this protein?
UPF0051 protein SSP1857.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: PSD_VEREI
Sequence: MPDRLAVLAQYALPKRALTTWAGKWASARLGGLTTALIRRFVARYDVNMAEAANPDMAGYASFNDFFTRALQPGARPLARADLICPVDGAISQFGRIGKDRIFQAKGHAYSTTALLGGDAAMAARFDDGHFATLYLSPRDYHRVHMPCAGELTRMVHVPGELFSVNPATACVVPGLFARNERVVCVFESAPGPGGPFALVLIGAAIVGSMATVWHGQVNPPRPGTLRQWDYAKGQVRLQQGQEMGRFLLGSTVVLLLPRGPLQFNPQWAPARPIMLGQAMAQRCAD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MNMA_NEOSM
Sequence: MKLMQELAEIIPGKAYNDVKVMVAMSGGVDSSTVAAYLHRVGYKVIGVTLQLHNNFTSTQTNRKTCCAGSDIFDAKRVAAQFGFLHYVVNMEETFRKEVIENFAESYLKGETPVPCVKCNQTVKFRDLMKIAKSLSVDALATGHYVRRLTTTNGVELHKGIDPSKDQSYFLFNTTREQLEFLRFPLGNLKKSETRDLARKLSVDISEKPESQDICFVNGKSYADVIKKFRPDAQRPGKILSTDGEVLGTHNGTIHYTIGQRHGLQLSAPIPLYVVKIDAQNNIIIVGTRDKLQQRSLYVKEVNWLDRKELTAGLECEVKLRSGADTVKGYLYPNGELLKVSLAEEPKCAIAPGQACVMYHGSKVLGGGWIV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNME_PROM0
Sequence: MDSIVTTEDTIAAIASAISIGKGGVAIIRVSGKDAINSCKKIVQTKSKYAWESHRVFRGFIQENKQNKFIDEVLILVMKSPNSFTGEDVVELHCHGGIIIVNKVLKILLSSNSRVRIANPGEFSQRAFLNGKIDLTQAESINQLINASNTRSAELAFSGIQGEIKKKIDDIKNDLINQLCEIEARVDFEEDFTDFDYTKYLKNIKKVKEKIELLIENAKRNSYIHNGISIALIGKTNVGKSSLLNLLAKKEKAIVTNIPGTTRDVIEVNLTINDIPMKIIDTAGIRETYEQIESIGIKKSFGKIKESDFIIYIYSLEEGFNEEDKKIIQEIPKEKLITILGNKKDLIDCKNINSNELKNTILMSIKNNDGEKLLIDTIIKKCGLKQVENINIFLNERHQTNLSACLSNLNDTDEIIENKLPFDLLSIELRDGIQNLSKITGQELTEELLDNIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_FUSNN
Sequence: MKIGVYAGSFDPITKGHQDIIERALKIVDKLIVVVMNNPTKNYWFNLDERKNLISKIFEGSDSIKVDEHAGLLVDFMAKNSCNILIKGLRDVKDFSEEMTYSFANKKLSNGEVDTIFIPTSEKYTYVSSTFVKELAFYNQSLTGYVDDKVIVDILNRAKEYRG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_PSET1
Sequence: MNSIQMLVGLANPGPEYANTRHNAGAWFIEQLAARYNCTLKHDPKYHGLTGKVIIQDQEFKLLIPTTYMNLSGKAVGSLANFFKIPVESILVAHDELDLEPGVAKLKKGGGHGGHNGLKDIIAKMANQKDFMRLRIGVGHPGHREMVTGWVLGKAAKADQEKMDAAIDEAVRCMEILAKDGVLKAQNRLHSFKP
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1479_LACP3
Sequence: MVGKRLWVTGYRAYELNVFGSNDPKLKVLKTSLKNTLMQFLDEGLEWLITGGQLGVEQWAVEVALGLKPLYPDFKIAMMVPFTDFGKQWNEDNQGQLAALRGQVDFSDAVSQAPYQQPAQLQGYTRFITIHTDAALLVYDPEFPGKAKWDYQAAEAMADRRDYPVQLITMDDLEETAQAMAEAENEHFQND
What are the official names of this protein?
UPF0398 protein LSEI_1479.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: RSMA_DESPS
Sequence: MSSYGRTRTDLKKHKLAPKKRFGQNFLVHKQTAEAIVRAGEVGEDDIITEIGVGLGALTVPMAHQAKHVYGIEIDNGIIKYHEEEQDLPDNVTLIHQDVLKVGFGDLAEKCGGKLKILANLPYSISHPLIFKLIEHRDIIPTATIMLQEEVADRLLAKPGTKEYGIPTILLGCCASIKKKMVLKPAEFHPRPKIDSAVITVDFTKPPELPEYNKELLSRVVRSAFSQRRKTILNTLSSASFFFAEKENKAKNKAMTEKTIEKAGFAVSLRPEVLSIQDFVRLTTVFEQEMNRTEE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_STRPB
Sequence: MITQRQNDILNLIVELFTQTHEPVGSKALQRTIDSSSATIRNDMAKLEKLGLLEKAHTSSGRMPSPAGFKYFVEHSLRLDSIDEQDIYHVIKAFDFEAFKLEDMLQKASHILAEMTGYTSVILDVEPARQRLTGFDVVQLSNHDALAVMTLDESKPVTVQFAIPRNFLTRDLIAFKAIVEERLLDNSVIDIHYKLRTEIPQIVQKYFVTTDNVLQLFDYVFSELFLETVFVAGKVNSLTYSDLSTYQFLDNEQQVAISLRQSLKEGEMASVQVADSQEAALADVSVLTHKFLIPYRGFGLLSLIGPIDMDYRRSVSLVNIIGKVLAAKLGDYYRYLNSNHYEVH
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: UVRC_STRTD
Sequence: MNGLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEINLIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCFYYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMAFERAAEYRDLIEAVSTLRTKQRVIRQDMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEALVGDEVKVFKPKRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAMVVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAGLQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFKSMTAIQQASVEDIQALGIPKKVAQALLDKLSQDSH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRM3A_DANRE
Sequence: MAALMYNVSRGLVMLGERSLFQRERYQILVNSRRFLRGLRRRPVAVLYPDGERETLIKSKRATDITSQGFTQKGKARKDVTERAAYKNCSGFVSERAEESSQINKLKLAGLRFEKAPAGDNRLARVSSVARSRAFRDKEGKVLLEGRRLICDALSAGASPQMIFFSLLERLQELPLDKLQQAKLIKVKYEDIKLWSDLVTPQGLIAIFSKPDASRLTFPKDARLQSVPLFLICDNVRDAGNLGTILRCAAAAGGDRVLLSKGCVDAWEPKVLRSAMGAHFRLPVFPNLDWDDISKHLPKNVIVHVADNYSTSTKQLVSGQTENVSSDDYSESDSDDDDDEEEDEDSLPHVKPQVYHECWAQRSAALVIGGETHGLSVEALRLAEETDGKRLFVPMAPGVESLNSAMAAGILLFEGRRQLLMLSDKLRRRARTKML
What is the function of this protein?
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1485 (Gm1485) in the mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
What are the official names of this protein?
rRNA methyltransferase 3A, mitochondrial, RNA methyltransferase-like protein 1A, rRNA (guanosine-2'-O)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: QUEC_METMP
Sequence: MKAICVLSGGLDSAVTSMFAKSKNYDISTVTFNYGQMALNQEIKSAKKISDILNADHHVIDINFVKEFSKSGLNTGNIPEPENEDLDDFEKSEKTMKAVWVPARNMIMFSIASGFAEGIGAEKIFSGLNKEEGVTFPDNTPEFIERFNKSLEYGTLNKVKMVAPLYELNKPEIAKLGKELELKLDLEVLKYSYSCYKDNGKDYLHCGTCESCMRRKRAFKEAGITDPTKYLVE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, Archaeosine biosynthesis protein QueC, PreQ(0) synthase.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MUTS_NEIMF
Sequence: MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYEMFFDDAVEAAKLLDITLTTRGQVDGEPVKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTVDKLDDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDGKEHAVAIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKSPTLMSTLDLCATHMGSRLLALWLHHPLRNRAHIRARQEAVAALESQYKPLQCRLKNIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSANGSSLLETLKAVFPENLSTAEQLRQAILPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAFEDKVLTAQEQALALEKQLFDGVLKNLQTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEFADYPVIHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPIDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQSLVLMDEVGRGTSTFDGLALAHAVAEHLLQKNKSFSLFATHYFELTYLPEAHAAAVNMHLSALEQGQDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKSAQKHLNGLENQAAANRPQLDIFSTMPSEKGDEPNVGNFVDKAEEKHFEGILAAALEKLDPDSLTPREALSELYRLKDLCKSVS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RS15_CLOBH
Sequence: MDKAKKQELMAKHARHEGDTGSPEVQIALLTERINHLNSHLKEHKKDHHSRRGLLMMVGKRRGLLNYLMREDIERYRAIIKELGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: EIF3A_DROYA
Sequence: MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFHFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYRAIEDIHGLMALSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPQLVSEDFRNLYNWLEVDFNPLNLCKRIQSIVDFIENGPENALLTPYIQSLKDVTIMRLIRQISQVYESIEFQRLMQLASFCNIFELEKLLVESVRHNDMQIRIDHQKNSIYFGTDLTESQREYRPDGPALQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRTQMVNHYHEIKDREHQRILQRQKIIEDRKEYIEKQNNAREEEEARRQEEESRKAKLAEQKRLEQEQEERERKRHQNEIQAIREKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAKRESEELQREAKELQSKLKSQEKKIDYFERAKRLEEIPLFEKYLAEKQVKDKEFWEATEKTRIENAIAERKDAVGQQERLKRMYPDRDEFLDALKKERASLYVEKLKKFEAALEAERKKRLADRIIRRREERRQAFLREKEEERLRKEEEIRLAQAAEERAAAEARRLEREAEDEKRRAQYEKQRAKEEEAERKIKEDRERLARELASERERTEKERDTWRPRGGDRPSAPSGGSGEWRRGAPTVNNERGIERGGDRIERGGDRIERGGERIERGGDRDRKDNEGADSSWRVRREPDSQRAAAPKDSGAPQSRDEKWRRGGERDRDFRNDGARRDRDDGPRRDRDDGPRRDRDDERSGFRRNDGPRRTEEPQRETGGNWRDAPRHADRENRRTAGGERRDRDVRETRGDQRGPAPKEAVSSGGGGNWRTTPAAREEKPATKRDQPQEKENKAADDGEWTSVKRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIA_STAEQ
Sequence: MSFASDMKNELTRIEVDESNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRIFNVEVEILVRKKMKLKKNNIYICRTKMLAKEILNDLGILKKGVFTHDIDPDMIKDDEMKRSYLRGAFLAGGSVNNPETSSYHLEIFSQYEDHSEGLTKLMNSYELNAKHLERKKGSIAYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIQLIDEEIGLENLPDRLREVAKLRVEHQEISLKELGEMVSTGPISKSGMNHRLRKLNELADKIRNGEQIEL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: RS11_BIFA0
Sequence: MAAQKQAARKTRRRDRKSIPVGQAHIKSTFNNTIISITDPSGAVVSWASGGDVGFKGSRKSTPYAAGMAAESAARKAMEHGVKKVDVFVKGPGSGRETAIRSLQSAGLEVGSITDVTPQAFNGVRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: CBPM_ECOBW
Sequence: MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: DNLJ_BACVZ
Sequence: MMDKETAKHRAEELRRTIDQYSYEYYTLDEPSVPDSEYDRLMQELIAIEEEHPELRTPDSPTQRVGGAVLESFQKVQHGTPMLSLGNAFNDDDLRDFDRRVRQAVGDGVAYNVELKIDGLAVSLRYEDGYFVRGATRGDGTTGEDITENLKTIRNIPLKMKRNLSIEVRGEAYMPKQSFEALNEERLKHEEEPFANPRNAAAGSLRQLDPKIAAKRNLDIFVYSIAELDEMGVETQSQGLDFLDELGFKTNQERKKCATIDEVIEMIEELQAKRADLPYEIDGIVIKVDSLDQQEELGYTAKSPRWAIAYKFPAEEVVTKLLDIELNVGRTGVITPTAVLEPVKVAGTTVSRASLHNEDLIKEKDIRILDKVVVKKAGDIIPEVVNVLIEQRTGEEKEFNMPTGCPECESELVRIEGEVALRCINPECPAQIREGLIHFVSRNAMNIDGLGERVITQLFREHLVRNVADLYKLTKEQVIRLERMGEKSTDNLISSIQKSKENSLERLLFGLGIRFIGSKAAKTLAMHFESLENLKQVTEEELLAVDEIGEKMADAVITYFRKEEMLELLNELEELGVNTLYKGPKKVKAEDSDSYFAGKTIVLTGKLEELSRNEAKAQIEALGGKLTGSVSKKTDLLIAGEAAGSKLTKAQELNIEVWNEAQLLGELKK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PSAC_AEGTA
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: TI201_ARATH
Sequence: MITGYSTPSAHVLMSSRAFKSSSYRAAAGQTQHYLARSSLPVVKNSWGSPPSPFNELPRVSRGVPLSYLSASSSLLLNGEQGSLSGTLPVLPVRRKTLLTPRASKDVPSSFRFPPMTKKPQWWWRTLACLPYLMPLHETWMYAETAYHLHPFLEDFEFLTYPFLGAIGRLPSWFLMAYFFVAYLGIVRRKEWPHFFRFHVVMGMLLEIALQVIGTVSKWMPLGVYWGKFGMHFWTAVAFAYLFTVLESIRCALAGMYADIPFVCDAAYIQIPYD
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.  Seems to be specific for photosynthesis-related pre-proteins.  Partially redundant with TIC20-IV, but not with TIC20-II or TIC20-V.
What are the official names of this protein?
Protein TIC 20-I, chloroplastic, Translocon at the inner envelope membrane of chloroplasts 20-I, AtTIC20-I.
What is the protein family that this protein belongs to?
Belongs to the Tic20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: MT3_BOSMU
Sequence: MDPETCPCPTGGSCTCSDPCKCEGCTCASSKKSCCSCCPAECEKCAKDCVCKGGEGAEAEEKKCSCCQ
What is the function of this protein?
Binds heavy metals.  Contains five zinc and one copper atoms per polypeptide chain and only a negligible amount of cadmium (By similarity).
What are the official names of this protein?
Metallothionein-3, MT-3, Metallothionein-III, MT-III.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.