PharMolix/UniProtQA huggingface dataset:
Protein: NHAA2_KINRD
Sequence: MKSSTREQTPVTSPTPHDPTPPTPPRGSTPLFSRGSWLETRRITDVLRKETIGGALLLLGTVVALVWANSPWSSSYAGLRDTVIAPSLLHPLHLDLTLGQWAADGLLAIFFFIAGLELKREFVAGDLRDPRRALVPVAAAVGGMAVPAVVYVLVARSAGDGALNGWAIPTATDIAFAVAVLAVISTHLPTALRTFLLTLAVVDDLLAITIIAIFYTDTLAVLPLLGALAVIAVFGLLVQKRIRSWWLLIPLAVVAWALMHASGIHATVAGVLLGFTVPVLRSRAAGGPEAGPGMAEHFEHVWRPLSAGFAVPVFAFFSAGVTVGGLSGLVDSLQDRVALGIVAGLVVGKAAGILGATAAVSRFTRARLDPSLSWWDVLGASLLGGIGFTVSLLIGELAFGAGSVRDEHVKVGVLTGSLLAAALAAVVLRARNRVYRRLHEAERVDEDADGVPDVYQAPRLNG
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KARG_PACMR
Sequence: MADAATISKLEEGFKKLQGATDCKSLLKKYLTKDVFDQLKAKKTSLGATLLDVIQSGVENLDSGVGVYAPDAEAYTLFAPLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCGRSMEGYPFNPCLTEAQYKEMEAKVFSTLSSLEGELKGSFYPLTGMAKDVQQKLIDDHFLFKEGDRFLQAANACRYWPSGRGIYHNDNKTFLVWCNEEDHLRIISMQMGGDLGQVYRRLVSAVNEIEKRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYSLQVRGTRGEHTEAEGGIYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: MYO6_HUMAN
Sequence: MEDGKPVWAPHPTDGFQMGNIVDIGPDSLTIEPLNQKGKTFLALINQVFPAEEDSKKDVEDNCSLMYLNEATLLHNIKVRYSKDRIYTYVANILIAVNPYFDIPKIYSSEAIKSYQGKSLGTRPPHVFAIADKAFRDMKVLKMSQSIIVSGESGAGKTENTKFVLRYLTESYGTGQDIDDRIVEANPLLEAFGNAKTVRNNNSSRFGKFVEIHFNEKSSVVGGFVSHYLLEKSRICVQGKEERNYHIFYRLCAGASEDIREKLHLSSPDNFRYLNRGCTRYFANKETDKQILQNRKSPEYLKAGSMKDPLLDDHGDFIRMCTAMKKIGLDDEEKLDLFRVVAGVLHLGNIDFEEAGSTSGGCNLKNKSAQSLEYCAELLGLDQDDLRVSLTTRVMLTTAGGTKGTVIKVPLKVEQANNARDALAKTVYSHLFDHVVNRVNQCFPFETSSYFIGVLDIAGFEYFEHNSFEQFCINYCNEKLQQFFNERILKEEQELYQKEGLGVNEVHYVDNQDCIDLIEAKLVGILDILDEENRLPQPSDQHFTSAVHQKHKDHFRLTIPRKSKLAVHRNIRDDEGFIIRHFAGAVCYETTQFVEKNNDALHMSLESLICESRDKFIRELFESSTNNNKDTKQKAGKLSFISVGNKFKTQLNLLLDKLRSTGASFIRCIKPNLKMTSHHFEGAQILSQLQCSGMVSVLDLMQGGYPSRASFHELYNMYKKYMPDKLARLDPRLFCKALFKALGLNENDYKFGLTKVFFRPGKFAEFDQIMKSDPDHLAELVKRVNHWLTCSRWKKVQWCSLSVIKLKNKIKYRAEACIKMQKTIRMWLCKRRHKPRIDGLVKVGTLKKRLDKFNEVVSVLKDGKPEMNKQIKNLEISIDTLMAKIKSTMMTQEQIQKEYDALVKSSEELLSALQKKKQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLALRRSLDSYPVSKNDGTRPKMTPEQMAKEMSEFLSRGPAVLATKAAAGTKKYDLSKWKYAELRDTINTSCDIELLAACREEFHRRLKVYHAWKSKNKKRNTETEQRAPKSVTDYDFAPFLNNSPQQNPAAQIPARQREIEMNRQQRFFRIPFIRPADQYKDPQSKKKGWWYAHFDGPWIARQMELHPDKPPILLVAGKDDMEMCELNLEETGLTRKRGAEILPRQFEEIWERCGGIQYLQNAIESRQARPTYATAMLQSLLK
What is the function of this protein?
Myosins are actin-based motor molecules with ATPase activity (By similarity).  Unconventional myosins serve in intracellular movements (By similarity).  Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments (PubMed:10519557).  Has slow rate of actin-activated ADP release due to weak ATP binding (By similarity).  Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration (By similarity).  Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway (PubMed:16507995).  Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells (PubMed:11447109).  Together with TOM1, mediates delivery of endocytic cargo to autophagosomes thereby promoting autophagosome maturation and driving fusion with lysosomes (PubMed:23023224).  Links TOM1 with autophagy receptors, such as TAX1BP1; CALCOCO2/NDP52 and OPTN (PubMed:31371777).  May act as a regulator of F-actin dynamics (By similarity).  As part of the DISP complex, may regulate the association of septins with actin and thereby regulate the actin cytoskeleton (PubMed:29467281).  May play a role in transporting DAB2 from the plasma membrane to specific cellular targets (By similarity).  May play a role in the extension and network organization of neurites (By similarity).  Required for structural integrity of inner ear hair cells (By similarity).  Modulates RNA polymerase II-dependent transcription (PubMed:16949370).
What are the official names of this protein?
Unconventional myosin-VI, Unconventional myosin-6.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: YIDC_ENDTX
Sequence: MQKNSILFVTLSAFTVFIWYFFFAQPSEQSYRQMMQLQNTVAVSESGVNKFKNADLNEFQIDDIYAKEEHINIETEQYKAVLTNKGGGVLSWSVKEKNGQWVDLVFPESAPVMANFPNLTYKVVSKSAEKIVFEYASKEGWKITKIYNLSDLYMHNLNISVEKNAKTPFPQIDLKWGPGLGTDSKELKENISLTRALVYTAVKPNKLKKLKDNFEPASLCKWTAVDNRYFLVAFIPKNSMDFDKILFSRLEKKHPCSVILKAAEPKDVDKKDYSVNFYLGPKDYKYLKTYDLGLEKTVDFGFFGFLGKIAFSILVFFYKLTHNYGWAIIMLTTIIQILVLPLTLKSFKSSAAMKRVQPVIKDIQTKYKDNPQRLKAEMLNIYQSQKVNPLGGCLPMLLQLPIFWAFFTMLRNAYELRNEGWILWVKDLSAADQFMQFGSFNLNLLPLMMGIGMFFQQRMTTVTSDPTQRKIMYIMPVIFTFMFWSFPSGLVLYWLTNSLISMIEQYFIMKKDAITVKHI
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KDSA_SALNS
Sequence: MKQKVVNIGDIKVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGNDKVILCDRGANFGYDNLVVDMLGFSVMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRGQVTELARAGMAVGLAGLFLESHPDPANAKCDGPSALPLAKLEQFLTQIKAIDDLVKSFDELDTEN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3913_SHESH
Sequence: MPRPRKCRRLSACVPCSMFKPNGIPSVELTKIQLEADEFEALNLGDVEKMSQLDAAARMGISRQTFGNLLASARKKVATAITRGHALVLPQERQES
What are the official names of this protein?
UPF0251 protein Ssed_3913.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: CYOE_YERP3
Sequence: MIKQYLQVTKPGIIFGNLISVIGGFLLASKGDIDYPLFLSTLLGVSLVVASGCVFNNYIDRDIDKIMERTKNRVLVKGLIDPKVSLIYASVLGIAGMLLLYVAANALAMMLAVIGFVIYVGVYSLYMKRKSVYGTLIGSLSGAAPPVIGYCAVTGQFDTGALILLLIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVIKGISVTKNHITLYILAFMVATLMLTLSGYAGYKYLVVAAAVSVWWLGMALRGYKATNDSVWARKLFVFSIIAITSLSVMMSVDFNVHSSAVLLTYAG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: T23O_KINRD
Sequence: MSGTAEENTREVEAGVVTDFTREMSYGEYLHLDELLAAQHPLSTPEHHDELLFIVQHQTSELWLKLVLHELRSAMRAIAADDLKTALKNIARVKHIQRTLTEQWSVLATLTPTEYAQFRGFLANSSGFQSQQYRAVEFALGNKNAKMLDVFAHDGPGHAQLTELLEAPSLYDEFLRHLARRGHDVPAELLERDVTKAHVHTPALVATFRVIYEDAQRYWTEYEACEELVDLEENFQLWRFRHLKTVERTIGFKRGTGGSSGVGFLARALDLTFFPELYAVRTEIGS
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: FOXO6_HUMAN
Sequence: MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWKNSIRHNLSLHTRFIRVQNEGTGKSSWWMLNPEGGKTGKTPRRRAVSMDNGAKFLRIKGKASKKKQLQAPERSPDDSSPSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEAAELEDDEALEALAPSSPLMYPSPASALSPALGSRCPGELPRLAELGGPLGLHGGGGAGLPEGLLDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Forkhead box protein O6.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. High nuclear localization after stimulation with growth factors (By similarity).
Protein: RF2_LACPL
Sequence: MKEGSFVELSEYKHLIEEMQSAVDDFRGSLDLDALNESIQENEARMAEPGFWDDQAAAQKVIDENNVLKGKYDTFKQLADEVGDLAVAYELLSEEPDAEMQAEFETDFQHAEHDLQQYRLNLLLDGPYDRNNAILEIHPGAGGTESQDWGAMLLRMYTRWAASHNFKVETVDYQAGDEAGIKSVTLLISGHNAYGYLRSEKGVHRLVRISPFDAAGRRHTSFASVDVMPELDDTVDVDIRPEDLKIDVYRASGAGGQHVNKTSSAVRITHVPTGIVVASQAQRSQLQNRQTALNMLRAKLYEREEEKKAKERAAIQGEQMDIGWGSQIRSYVFHPYTMVKDHRTNYESHHGQAVMDGDLDPFMDAYLQWKLAQRNPQ
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDR2_NICPL
Sequence: MEESFLGDELTRLRSNSRMSSWRSSQSIREVFGGSSDVFMKNYSTRWREMAEEEEKELKWAAIDRLPTYNRLRKGMMKEVMSNGRVVHHEVDMTKLGNQDKKVLMESILKVVEDDNEQFLRRLRNRTDRVGIEIPKIEVRFQNLSVGGDAYVGTRALPTLLNSTLNTIEAVLGLIHLSPSKKRVVKILEDVSGIIRPSRMTLLLGPPGSGKTTFLKALAGKSEKDLRVNGKITYCGHEFHEFVPQRTSAYISQHDLHHGEMTVRETLDFAGRCLGVGTRYDLLVELSRREKEAGIMPDPQIDAFMKATAIDGQETSLITDYVLKILGLDICADIMVGDDMRRGISGGQKKRVTTGEMLVGPAKAFFMDEISKGLDSSTTYQIVKFMRQMVHINDITMVISLLQPAPETFDLFDDVIVLSEGQIVYQGPRENVLEFFEYMGFRCPERKAIADFLLEVTSKKDQEQYWFRKSRPYVYISVPEFSESFNSFQIGEQIIEELTIPYDKYSVHRAALVKNKYGISSWELFKSCFTREWLLMKRSSFLYIFKTTQITIMATIALTVFLRTQMKAGTVKDSAKFWGALFFSLINVMFNGMQELAMTVFRLPVFFKQRNSLFYPAWAFALPIWVLKIPISLVESAIWIILTYYTIGFAPAASRFFKQLLAFIGVHQMALSLFRFIAAAGRTQVVANTLGTFTLLMVFILGGFIVSKDDIQDWMIWGYYLSPMMYGQNAIAINEFLDDRWSAPTNGSQPTVGKTLLHARGLFTTESWYWISIGALFGFSLLFNVLFIAALTFLNPIGDTKAVKVENGDKNNRRPQETAIVGDIQMAPTRSQANTSSVIPFPNNESRKGMILPFQPLSLAFNHVNYYVDMPAEMKTQGVEEERLQLLRDASGAFRPGILTALVGVSGAGKTTLMDVLAGRKTGGYIEGSINISGYPKNQTTFARVSGYCEQNDIHSPYVTVYESLLYSAWLRLASDVKTETRKMFVEEVMELVELKLLRNALVGLPGVDGLSTEQRKRLTTAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRKTVDTGRTVVCTIHQPSIDIFEAFDELLLMKIGGQVIYAGPLGHRSHKLVEYFETIPGVPKIRESDNPATWMLDVSSSSMEAQLVVDFAEVYANSNLYQRNQLLIKELSTPATCSKDLYFPTQYSQSFITQCKACFWKQHWSYWRNSQYNAIRFFMTVIIGILFGVIFWNKGNQIHRQQDLLNLLGATYAAVMFLGATNASAVQSVVAIERTVFYRERAAGMYSELPYAFAQVAIETIYVAIQTFVYSLLLFSMIGYQWTAVKFFYFYYFIFMCFTYFSMYGMMVVALTPGYQIAAIVMSFFLSFWNLFSGFLIPRPLIPVWWRWYYWASPVAWTIYGIFASQVGDRTDELELTGETEKIQVNEFLKEYLGYDHDFLLVVVFAHVGWVLLFFFVFAYGIKFLNYQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
Pleiotropic drug resistance protein 2, NpPDR2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PANB_HALSA
Sequence: MPTVNSVRRAGNTDEETDPVTMLTAYDAPTASVVDDAGVDMILVGDSVGNAKLGYDTTLPVSVDEIASATGAVARATADAVVVADMPFLSFGADETESVRNAGRMLKEEDADAVKLESGPHTVSLTETLTSLGIPVMAHLGLTPQHVNQLGGYFRQGTDQDSAERMLDLARDHEAAGAFALVLEHVPANVAADITDAIDIPTIGIGAGPDTDGQVLVISDVIGMSERSPPFSKQFGDVNREMAAAVDDYVDAVESGSFPAAEHSHVADDVDDVY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGI_XANOR
Sequence: MNLSSLSFRLLATLLGACVVVAPASAERIKDLAQVGGVRGNALVGYGLVVGLDGSGDRTSQAPFTVQSLKNLLGELGVNVPANVNPQLKNVAAVAIHAELPPFAKPGQPIDITVSSIANAVSLRGGSLLMAPLKGADGQVYAMAQGNLVVGGFGAQGKDGSRVSVNVPSVGRIPNGAIVERALPDVFAGTGEITLNLHQNDFTTVSRMVAAIDSSFGAGTARAVDGVTVAVRSPTDPGARIGLLSRLENVELSPGDAPAKVVVNARTGTVVIGQLVRVMPAAIAHGSLTVTISENTNVSQPGAFSGGRTAVTQQSTITATSEGSRMFKFEGGTTLDQIVRAVNEVGAAPGDLVAILEALKQAGALSAELEVI
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: Y020_PROM9
Sequence: MAGFGLPNFGQLTEAFKKAKQIQQDAQKLQDELENMEIEGESDDEMVKVWISGNQLPLRVEVQENILNSDKEKIEQNILQAIQKAHELSTTTMKERMNDLTGGLNLNLPGFDNTDS
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein PMT9312_0020.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SLYX_SHIDS
Sequence: MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: AROK_STRPD
Sequence: MTKVLLGFMGVGKTTVSKHLSMHCKDMDAIIEAKIGMSIAAFFEQHGEIAFRTIESQVLKDLLFANDNSVIVTGGGVVVLQENRQLLRKNHQHNILLVASFETLYQRLKHDKKSQRPLFLKYSKEAFYEFYQQRMVFYEGLSDLVIRVDHRTPEEVANIIEGY
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_METMA
Sequence: MQQADLTKRINELKLKRNAVILSHYYSRPEVQDIADFVGDSLALSQEAVRQDADVIVFCGVHFMGESAAILSPNKTVLLPEIDATCPMADMVNVEGLKILKEKHPEAPVVSYVNSSAAIKAESYICCTSANAVEVVNSLDADEVIFVPDKNLAAYVASRTDKKIIPWEGHCPTHHQILREDVLKMKEKHPRAEFIAHPECRPDVLELADHVASTRGMIVHAERSPAKEFIIGTECGLIHGLLKAVPEKTYYCVSEFACCPSMKMVNLEKVLTSLEKMQQRVIVPEDVRARAKEALDRMLAVKIN
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_MYCSS
Sequence: MFEGPVQDLIDELGKLPGIGPKSAQRIAFHLLSVEPPDIDRLTAVLNRIRDGVKFCEVCGNVSDADRCRICSDPRRDASLVCVVEEPKDVQAVERTREFRGRYHVLGGALDPLSGVGPDQLRIRELLNRIGERVDGVDVAEVIIATDPNTEGEATATYLVRMLRDIPGLTVTRIASGLPMGGDLEFADELTLGRALAGRRAMA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HIS3_METB6
Sequence: MLPLKFHEGGLIPVIVQDQKTREVLMMAYANEEAVRLTESTGSAHYYSRSRKKIWKKGEESGHFQKVGRILVDCDEDCLIYEVEQTGAACHTGYRTCFYRTLDGVTIGEKIFDPEKVYGKTGH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCC1_YEAST
Sequence: MSIVALKNAVVTLIQKAKGSGGTSELGGSESTPLLRGSNSNSSRHDNLSSSSSDIIYGRNSAQDLENSPMSVGKDNRNGDNGSDNEKANLGFFQSVDPRVISDLIIGLSDGLTVPFALTAGLSSLGDAKLVITGGFAELISGAISMGLGGYLGAKSESDYYHAEVKKEKRKFYDNSNLINREIEDILLEINPNFSDETIVSFIKDLQRTPELMVDFIIRYGRGLDEPAENRELISAVTIGGGYLLGGLVPLVPYFFVSDVGTGLIYSIIVMVVTLFWFGYVKTKLSMGSGSSTSKKVTEGVEMVVVGGVAAGAAWFFVKLLG
What is the function of this protein?
Has a role in both calcium and manganese homeostasis.  Involved in the transfer of iron and Mn(2+) from the cytosol to the vacuole for storage of these metals.
What are the official names of this protein?
Protein CCC1, Cross-complementer of CSG1 protein 1.
What is the protein family that this protein belongs to?
Belongs to the CCC1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane. Vacuole membrane; Multi-pass membrane protein.
Protein: SYS_AFIC5
Sequence: MHDIRWIRDNPEAFDAALGRRGLEPQAAALIALDEKRRGAIAAFEQAQARRNAASKEIGEAKKAKENARADALMAEVGELKTKLPEMDAAAKRLEEDLRKELAQIPNLPLAEVPEGADEHGNVQHHVYGEPRSYAFKPKEHVALGEGLGFMDFERAAKLSGARFVVLKSGLARLERAIGQFFLDVHTGEHGYTEVNPPLLVRDDAMFGTAQLPKFREDQFAAGSLDAEGQGYWLIPTAEVPLTNLVRESILDEKELPMRLTALTPCFRAEAGAAGRDTRGMIRQHQFTKVELVSITTPDESRNEHERMLSCAEEVLKRLGLHYRVMTLCTGDMGFASQKTYDIEVWMPGQISSQGEGGMYREISSCSVCGDFQARRMDARYRGPDNKPHFVHTLNGSGTAVGRALIAVMETYQQEDGSIAVPDVLQPYMGGLKVIERDR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALSR_BACSU
Sequence: MELRHLQYFIAVAEELHFGKAARRLNMTQPPLSQQIKQLEEEVGVTLLKRTKRFVELTAAGEIFLNHCRMALMQIGQGIELAQRTARGEQGLLVIGFVGSATYEFLPPIVREYRKKFPSVKIELREISSSRQQEELLKGNIDIGILHPPLQHTALHIETAQSSPCVLALPKQHPLTSKESITIEDLRDEPIITVAKEAWPTLYMDFIQFCEQAGFRPNIVQEATEYQMVIGLVSAGIGMTFVPSSAKKLFNLDVTYRKMDQIQLNAEWVIAYRKDNHNPLIKHFIHISNCQQTRTKESDAGT
What is the function of this protein?
Regulates the expression of the alsSD operon for acetoin biosynthesis.
What are the official names of this protein?
HTH-type transcriptional regulator AlsR, Als operon regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: MRAY_OCEIH
Sequence: MDLTGLLITIVVAFLITVLLSPIFIPFLRRLNFGQSIREEGPQSHQKKTGTPTMGGLMIIFSIIITSLIMASRTDEGINYQVWLLIFVLFGYGLLGFLDDFIKVAMKRNLGLTSKQKLFGQIIIALVFYFILRNQGFSTVIYVPGTELQFDIGWFYAVLVIFMMVGASNAVNLTDGLDGLLAGTAAIAFGAFAIIAWYGIPDHVVAVFSLAVVGALLGFLVFNAHPAKVFMGDTGSLALGGAIAAISILLKLEILLIIIGGVFVIETLSVIIQVISFKTTGKRVFKMSPLHHHYELLGWSEWRVVTTFWLVGLLFAMLGVYIEVGM
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CF120_CHICK
Sequence: MAARWRRILIVFVAAQVLCLVNTFEEEDVPEEWILLHVVQGQIGAGNYSYLRLNHEGKIVLQMQSLKGDADLYVSDMTLHPSFDEYELQSVTCGQDIVHVPAHFRRPVGIGIYGHPSHQESEFEMKVYYDRTVVQYPFGEASYNPEEMEANQKYSHSTEDESQDEESVFWTVLIGILKLILEILF
What are the official names of this protein?
UPF0669 protein C6orf120 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0669 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR7_OCEIH
Sequence: MKAALLYEGKAKKVYQSSEDEHQLVLSYKNDATAFNGEKKSQFEGKGRLNNEISSLIFQRLHEAGISTHFIKRLDSTQQIVQKTSIIPLEVVIRNLATGSITKRLGIKEKVSFTPPLLELFYKDDALGDPLINDEHALLLTDITETELAEIKDKAREVNAALQEIFQSIGIKLVDFKLEFGRNKDGEILLSDEVSPDTCRLWDIETNEKLDKDVFRQGTGDLITVYQEILNRLEVHV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: NU1C_MICAN
Sequence: MNQGIDLQESFIKSLTDLGLSGGLAKAIWMPLPMFLMIIAATVGVLVCVWLERKISAAVQQRIGPEYAGPLGVLQPVADGLKLVFKEDVVPAKADPWLFLFGPILVVMPVFVSYLIVPFGQNLLITDLNVGIFLWISLSSIAPIGLLMAGYASNNKYSLLGGLRAAAQSISYEIPLALSVLAIVMMSNSLSTIDIVEQQSGYGILGWNIWRQPVGFLIFWIAALAECERLPFDLPEAEEELVAGYQTEYAGMKFALFYVGSYVNLVLSALVFAVLYLGGWEFPIPVNALAGWLGVSETNPWLQIITASLGITMTVLKAYFLIFIAILLRWTVPRVRIDQLLDLGWKFLLPVSLVNLLLTAALKLAFPFAFGG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RLMN_HAEI8
Sequence: MCNNEAKMSELLSVQSDAPAKKINLMDLTRQQMREFFKELGEKPFRADQLVKWIYHFGEDNFDNMTNINKKLREKLKAVAEIKAPEVAVEQRSADGTIKWAMQVGEQQVETVYIPEADRATLCVSSQVGCALACTFCSTAQQGFNRNLTVSEIIGQVWRASKIIGNFGVTGVRPITNVVMMGMGEPLLNVANVVPAMEIMLDDFAYGLSKRRVTLSTSGVVPALDNLSKMIDVALAISLHAPNDELRDEIVPINKKYNIKTLIDSVNRYLNVSNANHGKVTIEYVMLDHVNDGIEHAHQLAEVLKNTPCKINLIPWNPFPEAPYAKSSNTRIDRFQKTLMEYGFTVIIRKTRGDDIDAACGQLAGDVIDRTKRTAMKRQFGQNIGVTEVN
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.