PharMolix/UniProtQA huggingface dataset:
Protein: Y3568_PSEAE
Sequence: MTYLQQHARSIAEPAAFWAEQARSLAWYQAPANILESLPDGTHRWFADGRLNSAYLALDRQIEEGRGEQTALIYDSPVTGTQDRYSYLRLRDEVARLAGALRALGVGKGDRVIIYMPMVPQAAMAMLACARLGAVHSVVFGGFAPYELALRIDDATPKLVLTASCGLEFDRVIEYKPLVDKALELAIHQPAHVMVWQRPQAPARLHPGRDLDWQDCLAAAEPADPLPVASGDPLYIMYTSGTTGKPKGIVRDNGGHAVAVRYAVRTIYGMQAGDVWWGISDVGWVVGHSLIVYGPLMCGCTTVFYEGKPVRTPDAGAYWRVIEEHRVNSLFCAPTAIRAIRKEDPHGERVKRYDLGSLRHLFLAGEKLDSSTQHWLEEHTGRPVHDHWWQTETGWPVTAPCIGIAGHDLRAGSTNRAVPGYHVQVLDDEGRPLGANRQGAIVIALPLPPGCAQTLWGDHPRYLQAYLGNYPGYYHTGDGGYLDEDGFVYIMGRTDDVINVSGHRLSTGEMEERVAQHQAVAECAVIGVRDELKGHVPLGLVVLKDDAGIAAEQLQRELVALVREQIGALACFQRVVVVKRLPKTRSGKILRAVLRKIADGEDYAAPSTIDDPTILGEIEAALRVRKAG
What are the official names of this protein?
Uncharacterized protein PA3568.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GG6LA_HUMAN
Sequence: MWPQPRLPPHPAMSEKTQQGKLAAAKKKLKAYWQRKSPGIPAGANRKKKVNGSSPDTATSGGYHSPGDSATGIYGEGRASSTTLQDLESQYQELAVALDSSSAIISQLTENINSLVRTSKEEKKHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEERLCEQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELEKSGGAEEPRGSESAAAARPVPGAPVPQGAWMCGQAGWTPQEHPGLSGEAVGTGEAAGGAEEAACHSFRAAENRELNITII
What are the official names of this protein?
Golgin subfamily A member 6-like protein 10.
What is the protein family that this protein belongs to?
Belongs to the GOLGA6 family.
Protein: BRS3_SHEEP
Sequence: MSQRQPQSPNQTLISTTNDTESSSSVVPNDSTNKRRTGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDVTHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGCIWIMSMIIALPEAIFSNVYTFQDPDKNVTFKACASYPVSERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQRHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYRSFTSQTYMDSSTVHLFVTIISRILAFSNSCVNPFALYWLSNTFQQHFKAQLFCCKAGRPDPTAANTPLDNLAVMGRVPGAASTQMSEISVSPFTGCSVKKEDDRV
What is the function of this protein?
Role in sperm cell division, maturation, or function.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
What are the official names of this protein?
Bombesin receptor subtype-3, BRS-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YAAW_ECOLI
Sequence: MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLMRNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKLKADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKLLAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVTIPAVLQIACLRRMVSATQV
What are the official names of this protein?
UPF0174 protein YaaW.
What is the protein family that this protein belongs to?
Belongs to the UPF0174 family.
Protein: PTNAB_STRP6
Sequence: MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDDLYGHFNNAIQQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQAYTERLMDAGAGIEQVAANIIKESKDGIKALPEDLNPVEETAATEKVVNALQGAIPAGTVIGDGKLKINLARVDTRLLHGQVATAWTPASKADRIIVASDEVAQDDLRKQLIKQAAPGGVKANVVPISKLIEASKDPRFGNTHALILFQTPQDALRAVEGGVEINELNVGSMAHSTGKTMVNNVLSMDKEDVATFEKLRDLSVTFDVRKVPNDSKKNLFELIQKANIK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ManXYZ PTS system is involved in mannose transport.
What are the official names of this protein?
PTS system mannose-specific EIIAB component, EIIAB-Man, EIII-Man.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: FEMB_STAAN
Sequence: MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLLGIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQCLYVKLDPYWLYHLYDKDIVPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWMGVLNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGFVSKTDDYFYNFIDTYGDKVLVPLAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDKQMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEKYNQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELIGDFYKPIHKVKYWLFTTLDKLRKKLKK
What is the function of this protein?
Catalyzes the formation of the pentaglycine interpeptide bridge, which is characteristic of the S. aureus peptidoglycan.  Adds glycines 4 and 5 of the pentaglycine bridge, using glycyl-tRNA(Gly) as donor.  Involved in resistance to methicillin (By similarity).
What are the official names of this protein?
Aminoacyltransferase FemB, Factor essential for expression of methicillin resistance B, N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-(N6-triglycine)-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine:glycine glycyltransferase.
What is the protein family that this protein belongs to?
Belongs to the FemABX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRA1_MOUSE
Sequence: MAELYVKPGNKERGWNDPPQFSYGLQTQTGGPKRTPLTKRVAAPQDGSPRAPETSGPPPVDHPPPSSKASRPPPMGSCPATGVEPPSSPVIESETLIEDVLRPLEQALEDCHGHTKKQVCDDISRRLALLREQWAGGKLSIPVKKRMALLVQELLHHQWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAEKKSLSSEETKEEKFTVEPENQTIPGFQQPS
What is the function of this protein?
Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors.  Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2).  Enhances cellular proliferation and differentiation and promotes apoptosis in vivo.  May play a role in tumorigenesis (By similarity).
What are the official names of this protein?
Steroid receptor RNA activator 1, Steroid receptor RNA activator protein, SRAP.
What is the protein family that this protein belongs to?
Belongs to the SRA1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: THIC_CLOBH
Sequence: MNYTTQMDAAKKGIVTKEMEIVAKKENMNVKDLMELVSKGKVAIPANKNHKSLDPEGIGQGLRTKINVNLGISKDCYNIDMELEKVQKAIDMKAEAIMDLSCFGKTEEFRKRLIDMSPAIIGTVPIYDAVGFYDKELKDITSEEFLKVAEKHAENGADFLTIHVGMNRKTAATFKKNPRRMNIVSRGGSLLYAWMELNNKENPFYEGFDKLLDICEKYDVTLSLGDACRPGCIEDSTDASQIEELIALGELTKRAWERNVQVIIEGPGHMTLDEIETNMKIEKKLCHGAPFYVLGPIVTDIAPGYDHITSAIGGAIAATHGADFLCYVTPAEHLRLPNLDDMKEGIIASKIAAHAADLAKGVKGARDWDNAMAKARRDLDWERMFELSIDEEKARRYREESKAKSKDSCTMCGKMCAVRNMNRVTEGKDLNMLRDDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: MGTA_MYCS2
Sequence: MRVAIVAESFLPNVNGVTNSVLRVIDHLRRTGHEVLVIAPDTPRGQPPADRIHDGVRVHRVPSRMFPKITSLPLGVPRPRMIGVLRGFDPDVVHLASPALLGYGGLHAARHLGVPSVAVFQTDVAGFAESYGMGVASRAAWAWTRHLHSRADRTLAPSTSAMENLAAHRIPRVHRWGRGVDITGFVPSARDEHLRRTWSPDGRPIVGFVGRLAPEKHVERLAVLAARDDLQLVIVGDGVDRVKLQTVLPTAVFTGELRGAALAAAYASMDVFVHPGEHETFCQTVQEAMASGVPVIAPDAGGPRDLVAPCRTGLLLDVDGFECALPAAVTHLIAERRRYGIAARRSVLARTWPVVCDELIGHYEAVLGRRSLRAA
What is the function of this protein?
Catalyzes the addition of a mannose residue from GDP-D-mannose to GlcAGroAc2 to generate 1,2-di-O-C16/C18:1-(alpha-D-mannopyranosyl)-(1-4)-(alpha-D-glucopyranosyluronic acid)-(1-3)-glycerol(ManGlcAGroAc2).
What are the official names of this protein?
GDP-mannose-dependent alpha-mannosyltransferase, Guanosine diphosphomannose-dependent alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: RLMC_YERPE
Sequence: MHCAQYTAGRCRSCQWLDKPYPQQLADKQHHLESLLAGHAVTQWLAPVFGRESAFRNKAKMVVSGSVERPLLGMLHRDGTPVDLCACPLYPPSFEPVFTVLKTFIARAGLTPYNVARKRGELKFLLLTESTYNGELMLRFVLRSETKLAQLIAALPWLQQQLPQLAVISANIQPVHMAILEGEREIPLTEQQALPERFNQVPLYIRPQSFFQTNPQVAASLYATARQWVQEHEVHSMWDLFCGVGGFGLHCAGPETQLTGIEINAEAIACARQSAEQLGLKNVSFAALDSTRFATAEAQIPELVLVNPPRRGIGRELCDYLSQMAPKFILYSSCNAETMAKDISLLAGYHIERVQLFDMFPHTSHYEVLTLLTLRR
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: MENE_HAEIN
Sequence: MYPWQDFAIQPDFSDKIALRTTQGDMLTWIELTTKINQTVAFLQKKGVNAESAVAFVGKNSEKILFLYLATIQLGAKVLGINPAFPQEKIAKLCEFYQIDFCFYDKDLLNLQEIDVFTQKADFFRPATMTLTSGSTGLPKAVVHNVQAHLDNAKGVCNLMKFDCNQSWLLSLPLYHVSGQGIVWRWLYCGAQLHFPEDDFYASLLKTTHVSLVPTQLQRLLDYLQENPSISFATRHILLGGAHIPTELTQNMLKYGIETYSGYGMTEMASTVFAKKSDRKQGVGQPLLGREYCLVNDEIWLKGAGLAMGYWKDRQIVPLTNNQGWIQTKDKGIWQEGELVIIGRLDNMFISGGENIQPEEIEQVIIQHSSVNQVFVLPQKNKEFGQRPVALVDFNEPFSKSAVENLMFFLQDKLARFKQPIAYYPLPLMLEKGIKISRKQLADWLAKRDEIN
What is the function of this protein?
Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA).
What are the official names of this protein?
2-succinylbenzoate--CoA ligase, o-succinylbenzoyl-CoA synthetase, OSB-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.
Protein: SBK1_MOUSE
Sequence: MSVGCPEPEPLHSLPCCGPGAAPVPGAGVPLLTEDMQALTLRTLAASDVTKHYELVRELGKGTYGKVDLVAYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFETEECYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHSRQLVHRDIKPENVLLFDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGRADGFAVDTGVDVWAFGVLIFCVLTGNFPWEAASGADAFFEEFVRWQRGRLPGLPSQWRRFTEPALRMFQRLLALEPERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRLPGSLRLEAPGPLKRTVLTESGSGSRPSPPSVGPVVPVPVPVPVPVPEAGLAPPAPPGRTDGRTDKSKGQVVLATAIEICV
What is the function of this protein?
May be involved in signal-transduction pathways related to the control of brain development.
What are the official names of this protein?
Serine/threonine-protein kinase SBK1, SH3-binding kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F166A_MOUSE
Sequence: MTATQKHNLFTPEPHYIPGYAGFYPQLRYQVGNTYGRTTAQLLTDPSVQKSPCSVLSPMTKPKFIEDFSKSKPPWIPCRDLREPYIPHYTSLKPYKNFEILGQLPRQDVDTQGPPQVENRQGPLTAGFMPYPPYPACPPGRKGEARDLGHPGLLLAYGEEAWKDAAPLQDTPGKNNQLYHCRRDEYLPPHPPQETLDVGRFQRLPQLDHPNLIQRKAISGYAGFVPRFAWVMGMNYRDGVTQAMDDFDKNQFVFRHPVCALGERLPRTHWPNTTIYRSQGLIPFYMGFIPSMQDNYALTFGNSTRRAYQKELDRRSHTL
What are the official names of this protein?
Protein FAM166A.
What is the protein family that this protein belongs to?
Belongs to the UPF0605 family.
Protein: PEPT_BACMK
Sequence: MKQELIERFTRYVKIDTQSNEESHTVPTTPGQIEFGKLLVEELKEIGLSEVTMDEKGYVMATLPANTDKDVPVIGFLAHLDTATDFTGKNVKPQIHENFDGNAITLNEELNVVLTPEQFPELPSYKGHTIITTDGTTLLGADDKAGLTEIMVAMNYLIHNPQIKHGKIRVAFTPDEEIGRGPSHFDVEAFGASFAYTMDGGPLGGLEYESFNAASAKLTFRGTNTHPGTAKNKMRNASKLAMEFDRQLPVEEAPEYTEGYEGFYHLLSLNGDVEQSKAYYIIRDFDRNHFEARKNNIKDIVKNMQEKYGEDAIVLEMNDQYYNMLEKIEPVREIVDIAYEAMKSLNIEPNIHPIRGGTDGSQLSYMGLPTPNIFTGGENYHGKFEYVSVDTMEKAVQVIVEIARRFEEQA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YLBH_BACSU
Sequence: MRVISGSKKGRSLKAVAGTSTRPTTDKVKESIFNMIGPYFDGGRGLDLFAGSGGLGIEALSRGFEHCIFVDRDFKAIQTVKSNLKTLELTKHAQVYRNDAERALHAAAKRETGFRGIFLDPPYKEQKLKALLTLIDEYQMLEEDGFIVAEHDREVELPETVGDLVMTRKETYGLTGVAIYKKRG
What is the function of this protein?
May catalyze the S-adenosyl-L-methionine-dependent methylation of a specific base in rRNA.
What are the official names of this protein?
Putative rRNA methyltransferase YlbH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmD family.
Protein: OGT_MYCTU
Sequence: MIHYRTIDSPIGPLTLAGHGSVLTNLRMLEQTYEPSRTHWTPDPGAFSGAVDQLNAYFAGELTEFDVELDLRGTDFQQRVWKALLTIPYGETRSYGEIADQIGAPGAARAVGLANGHNPIAIIVPCHRVIGASGKLTGYGGGINRKRALLELEKSRAPADLTLFD
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YVDB_VACCC
Sequence: MGSDIPVLNALNNSNRAIFVPIGPSNCGYSVLLIDILILLSGNRGSTSSKNKSLITSGLFINKNLAILYILLLSNLAIVL
What are the official names of this protein?
Uncharacterized 8.5 kDa protein.
Protein: CATB_COTJA
Sequence: LPDTFDSRKQWPNCPTISEIRDQGSVSVEVSAEDLLSCCGFECGMGCN
What is the function of this protein?
Thiol protease which is believed to participate in intracellular degradation and turnover of proteins.  Has also been implicated in tumor invasion and metastasis.
What are the official names of this protein?
Cathepsin B, Cathepsin B1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: CLCA1_MESMA
Sequence: MNTFVVVFLLLTAILCHAEHALDETARGCNRLNKKCNSDGDCCRYGERCISTGVNYYCRPDFGP
What is the function of this protein?
May increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells.
What are the official names of this protein?
Toxin BmCa-1, BmKCaTx4, Calcium channel toxin BmCa1.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_MOOTA
Sequence: MLHLTIVAVGRVREKYLVAGIEEYLKRLRPYARVRILEAPEEKVPDKPSPAGVEQILASEGRGIGRLIPPSSFTVALDREGVMLSSEELAGRLADLALAGKNEVALIIGGTLGLATFILQQADLRLSFSRFTFPHQLMRLILLEQLYRAFKIQRGETYHR
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AOTC_XYLFT
Sequence: MALKHFLNTQDWTCSELNALLTQARAFKHNKLGNALKGKSIALVFFNPSMRTRSSFELGAFQLGGHAIVLQPGKDAWPIEFDTGTVMEAETEEHICEVARVLGHYVDLIGVRAFPKFLDWTYDRQDIVLNSFAKYSPVPVINMETITHPCQELAHIMALQEHFGTTDLRGKKYVLTWTYHPKPLNTAVANSALTIATRLGMDVTLLCPTPDYVLDERYIDWARQNIADTGSTFQVSHDIDNAYRGADVIYAKSWGALPFFGNWAMEKPIRDQYRHFIVDEAKMALTNNAVFSHCLPLRRNVKATDAVMDGSNCIAIHEAGNRLHVQKAIMAALASQ
What is the function of this protein?
Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-acetyl-L-ornithine to produce N(2)-acetyl-L-citrulline.  This is a step in an alternative arginine biosynthesis pathway.  The enzyme has no activity with ornithine.
What are the official names of this protein?
N-acetylornithine carbamoyltransferase, N-acetyl-L-ornithine transcarbamylase, AOTCase, Acetylornithine transcarbamylase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. AOTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKGR_ECOLI
Sequence: MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY
What are the official names of this protein?
Uncharacterized membrane protein YkgR.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: COLI_BALPH
Sequence: SYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF
What is the function of this protein?
Anorexigenic peptide.  Increases the pigmentation of skin by increasing melanin production in melanocytes.
What are the official names of this protein?
Pro-opiomelanocortin, POMC, Corticotropin-lipotropin.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted.
Protein: TPX_STRSA
Sequence: MTTFLGNPVTFTGKQLQVGDTAHDFSLTATDLSKKTLADFAGKKKVLSIIPSIDTGVCSTQTRRFNQELSDLDNTVVITVSVDLPFAQGKWCAAEGIENAVMLSDYFDHSFGRDYAVLINEWHLLARAVLVLDENNTVTYAEYVDNINTEPDYDAAIAAVKSL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: MRN1_MEGVI
Sequence: YLDVKQLANYLLCIGNGQVFNGRKTCQIGCRAVCQQPGCSGYKECEQIPNIRLHKYRCHCNEA
What is the function of this protein?
Has antimicrobial activity against Gram-positive bacteria and fungi.
What are the official names of this protein?
Megourin-1.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_VIBA3
Sequence: MSITNEQILDAVAEMSVMQVVELIEAMEEKFGVTAAAAVVAGGASAEAAAEQTEFDVILTAAGANKVQVIKAVRGATGLGLKEAKGLVDSAPAALKEGVDKAEAEALKAQLEEAGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: BSPH2_MOUSE
Sequence: MEVMSHLVHWVFLAVYMYELNAELISHLHPPEQEISTDSCVFPFVYADGFHYSCISLHSDYDWCSLDFQFQGRWRYCTAQDPPKCIFPFQFKQKLIKKCTKEGYILNRSWCSLTENYNQDGKWKQCSPNNF
What is the function of this protein?
Binds sperm in vitro but has no effect on sperm capacitation.  Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes.
What are the official names of this protein?
Binder of sperm protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the seminal plasma protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXH_SHEFN
Sequence: MSDLSDIRREYTQGGLRRANLPVNPMDLFEQWMQQAKDAQLSDPTAMCVATVDEDGQPFQRIVLLKKFDDNGFVFFTNLESRKAKQIATNSKISLLFPWHPLERQVAVLGEAEPLSMLDVAKYFMSRPKDSQIAAWVSKQSSKISARQALEGKFAEMKAKFAQGEVPLPKFWGGYLVRPASIEFWQGGEHRLHDRFIYTKTDADWNIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RL21_CERS1
Sequence: MFAVLKTGGKQYKVQAGDVLRVEKLACEAGDKIQFNDILMVGGDSVTVGAPFVAGAAVQAEVIAQIKGEKTIHYVKRRRKHSSQRTKGHRQQLTLLRVTDVLASGADASGVAAATGTADARRAAHNASAKE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ZN569_MOUSE
Sequence: MTESEGLVTFKDVAIDFTQEEWKQLDPTQRNLYRNVMLENYNNLITVGPPLTKPEVIFKLEQEEEPCVVEREVLWRPCPGEILGIDEHQKIQDGQVFEGIVVTSEASECPEEFASTFFPNADSIPSMHSLFECDGVGECLEPNFGDDDVQYPLPEEQFEYDDAMQPFHTSSPHFVLTPFKCNHCGKGFSQTLDLIRHLRVHTGGKLYECHQCGKGFSHKEKLINHHKLHSREQCYECSECGKTFIKMSNLIRHQRIHTGEKPYVCQECGKSFGQKSNLIDHEKIHTGEKPYKCNECGKSFSQKQSLVAHQKVHTGEKPYACNECGKAFPRVASLALHMRGHTGEKPYKCDKCGKAFSQFSMLIIHVRVHTGEKPYECGECGKAFSQSSALTVHIRSHTGEKPYECKECRKSFSHKKNFITHQKIHTREKPYGCNECGKAFIQMSNLVRHQRIHTGEKPYLCKECGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFITHQKVHTGEKPYDCNKCGKAFSQIASLTLHLRSHTGEKPYECEKCGKAFSQCSLLNLHMRSHTGEKPYVCNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSSLTIHIRGHTGEKPFDCSNCGKAFSQISSLTLHMRKHTGEKPYVCIECGKAFSQKSHLVRHQRIHTH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 569, Mszf21, Zinc finger protein 74, Zfp-74.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXA_BRUSU
Sequence: MKETFIHPTALVEPGVELGQGVSVGPFCHVQSGAIIGNDCELMSHVVITGATTLGAGTKVYPHAILGCDPQNNKHKGGPTRLNVGVNCIIREGVTMHKGSDNARGYTSIGDNCSFLAYAHVAHDCDIGDYVTFSNNVMIGGHTSIGHHAILGGGAAVHQFVRVGHHAFIGGLAAVVSDLIPYGMAIGVHAHLGGLNIIGMKRSGMERKEIHNLRHAVRMLFDRTKPIRQRAQDVLAAIPDSPTVSDMISFINVDTKRAYCTPPLDAAHGGAGHDSDED
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAV2_PLEMO
Sequence: MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSGQDRDPHRLNSHLKLGFEDVVAEPVTTHSFDKVWICSHALFEISKYVMYKFLTVFLAIPLAFLAGILFATLSCLHIWIIMPFVKTCLMVLPSVQTIWKSVTDAIIAPLCTSIGRSFSSVSLQLSQD
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.  The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.  Positive regulator of cellular mitogenesis of the MAPK signaling pathway.  Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
What are the official names of this protein?
Caveolin-2.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin (By similarity). Tyr-27- phosphorylated form is located both in the cytoplasm and plasma membrane. CAV1-mediated Ser-23-phosphorylated form locates to the plasma membrane. Ser-36-phosphorylated form resides in intracellular compartments.