PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_ALKCK
Sequence: MHTIAIGLNYKTAPVEIREKLVFSEHQLPEALKKLRSSKSMMECVILSTCNRTELYVVADQLHTGRYFAKAFLAEWFSVDMEDVTPYLVIRENDHAIEHLFRVACGLDSMVIGETQILGQVKQAFLLAQEEKVTGTVFNQLFKQAVTLGKRVHSSTEISSQAVSVSYAGVELGKKIFGTFSGKHVLILGAGKMSELTAKHLYANGAASISVMNRTKENAVELASQFAGTARSFAELNDALKEADVVISSTGARDFVVTKENAADALKKRKGRPLFAIDIAVPRDIDPEIATISDVYLYDIDDLQNIVETNKKERKKEAEKIGVMIEAEIDDFKAWLNTLGVVPLITALREKALQIQGDTMESIERKLPHLSERDIKVLNKHTKSIVNQLLRDPLTRVKELAAEPDAKHSLELFKTIFALEAQIELAEKAEADHAEQSWKEGQRPSLNQGMALRT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: QUEF_THEPX
Sequence: MTDKYKERRFDTYGYEKIDKEVLESIEYEYPEKNTIVEYITNEFSSVCPWTGLPDNAKLTIRYIPSKKLVELKSLKYYLTSYRNVGILQEHAINRILDDLVELLQPKFMEIIGEFQERGGIATRIVAKYEKEK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2BC_PSEAU
Sequence: NLIQFGNMIQCANKGSRPSLDYADYGCYCGWGGSGTPVDELDRCCQTHDNCYEQAGKKGCFPKLTLYSWKCTGNAPTCNSKPGCKRFVCACDAAAAKCFAKAPYKKENYNIDTKKRCK
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 PA-12C, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CTL1L_AEDAE
Sequence: MGCFESKPSEQHQPTAVRGCTDIFWLVVYILFWIALLVIAVFSFVYGNPLRVINGYDSFGNTCGVSSNEKFSHFPLSGMNTKDKPYVFFLDIKELRQTLKICVKECPKKEIGNAMELYRYYEERDTKYCRYDFNMSLLTAPDASGPKYFAFAGPCPKFPVYESSSVLHRCIPSGKNAPTKVVKDMYALVNSFGAAQQVFSDIYKTWPTVLLLVGLSLIFSIILIMMLHWLTAIISWLICIFVAVASIGITAVLWWSYYKQKHSIDTDTKLSYLEELVRNETTIYVLAILATCIMIILLVVIYYLREKLSGLAALFEEAGKCMLQIPGLAGPPVLAFIALAVFLSFWMVVIVCLATANYPNVKPLLPFTQLKENPNKTEAAIKPDMSVNNNTYKSFDLVEYPEADFLRHMLWIYIIGLVWTSEFIFACQQLVISGAVAYWYFRKPTDTPVLNAIAKLVKYHLGSVAKGSFIITLFKIPRLILTYLYAKLKRHQQEGSECASCCLKCCICSFWLLEKFIRYLNHNAYTVIAIESVNFCPAAKIAWNALVTNALQVATINGIGDLVLFLGKLAVAALCGLISILMLRDNPDVHFYMAPVIIITLFSFFVAHIVLSLYEMVVDTLFLCVCEDRTINGNSGRWKQSNLAHLLGESPEQDAVEAPMQVVELTPITKQPFSVQSLQMTEIDDKGAV
What are the official names of this protein?
Choline transporter-like 1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VTSS2_HYOMU
Sequence: SRWWKDLDFVTTLPYARDRAVECYFWTMGVYAEPQYSQARVMLAKTIAMISIVDDTFDAYGIVKEFEVYTDAIQRWDISQIDRLPEYMKISYKALLDLYDDYEKELSKDGRSDVVHYAKERMKEIVRNYFIEAKWFIEGYMPSVSEYLSNALATSTYYLLTTTSYLGMKSATKEHFEWLATNPKILEANATLCRVVDDIATYEVEKGRGQIATGIECYMRDYGVSTEVAMEKFQEMAEIAWKDVNEEILRPTPVSAEILTRILNLARIIDVTYKHNQDGYTHPEKFKPHIIALLVDSIEI
What is the function of this protein?
Sesquiterpene synthase that catalyzes the formation of vetispiradiene from trans,trans-farnesyl diphosphate.  The initial internal cyclization produces the monocyclic intermediate germacrene A.
What are the official names of this protein?
Vetispiradiene synthase 2, HVS2.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGK5_CAEEL
Sequence: MIFPIGIPMISKKRKSAQEAVSLREAAERRSQFARVPARSVSAPPRKKWFRSKQQLSGAADGMDGSSRAGSQEIVCDEFTKKLVAAITTWHDIHSSLLQLSIERSSNDSNEEHENVSVSSESSWSSASDSESDEDSATGRDSTNNHLSASAARFSISNPDLTNCQIKQMFPEMADHWRKALAKSPVVRRTAADQETSNPVNKHRSSRYWIEDEGDYHILPSEHVWLPSSTGSSASADSECYVGEKDCRRSGEKRRCAACHIVAHTNCFSLLAKLNLNCKTTFRDYATKKTPSKESTDGLTAHHWVHKWRHEGRCNTCAKSFQQKMFFQGKEKKETIAVTCSWCKESYHLKNCFARDKLEERCNRGALKEMIVPPTWILRLANRKRSSRTPSHPRKHKKSHRQFVVKPTDLWSSGPSQPLLVFVNPKSGGNKGSKALHTLCWLLNPRQVFDITSLKGPKFGLEMFRKVVTQLRILVCGGDGTVGWVLSTLDNLNWPAYPPMAIMPLGTGNDLARCMGWGGVFSDEPISQLMQAILHETIVTHLDRWRIDVEPNTSCNLEEEDDGMQSALPLTVMTNYFSIGADAHVALQFHHSRSANPQMLNSRLKNRIAYGGLGTIDLFKRSWKDLCEYITLECDGVDVTPRIKELKLHCILFHNITYYAGGTIPWGESSDNKPSCCDGKVEVLGFTTATLAALQMGGKGERIAQCSRVRVITNKAIPMQVDGEPCLLAPSIITLGFHSKVPMLKREKKTPCTPNLMRRGTRYGQKDSQVQSTSLIIQLPVIVVGRADYDNYKDCFERLKDTAYEIGIVNVESEAELDSARVLIQRLLVEHNSLPYEPDKNWRFLDYVSNAEEGTFRVSRQQEHVQSVSDVCNTDECLLILDHAFPSITDREAVELFQPQQPIPSTSTSAAPRYHNSRRISETLRIVLSSDAQETHL
What are the official names of this protein?
Putative diacylglycerol kinase K06A1.6, DAG kinase, Diglyceride kinase, DGK.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
Protein: GD1L1_MOUSE
Sequence: MATPNNLTPTNCSWWPISALESDAAKPVETPDAPEASSPAHWPKESLVLYHWTQSFSSQKRLQVRLVIAEKGLACEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRDNIISDYDQIIDYVERTFTGEHVVALMPEAGSPQHARVLQYRELLDALPMDAYTHGCILHPELTTDSMIPKYATAEIRRHLANATTDLMKLDHEEEPQLSEPYLSKQKKLMAKILEHDDVSYLKKILGELAMVLDQIEAELEKRKLENEGQTCELWLCGCAFTLADVLLGATLHRLKFLGLSKKYWEDGSRPNLQSFFERVQRRFAFRKVLGDIHTTLLSAVIPNAFRLVKRKPPSFFGASFLMGSLGGMGYFAYWYLKKKYI
What are the official names of this protein?
Ganglioside-induced differentiation-associated protein 1-like 1, GDAP1-L1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
Protein: CODY_CLOBH
Sequence: MSSLLDKTRMLNRILQKSGTEPVDFEDICDLLSDVLACNVYIISRKGKILGSKFYSGFECDEVREVVLKENRFPDFYNNKLLNVNETLSNSPNHDKCVFDNLKDCSINNKLSTIVPINGNRERLGTLLLARFDKEFTDEDLVLAEYSATIIGLEILRSKQDQIEEEARKKAVVQLAIGTLSYSELEAVEHIFNELDGTEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGTHIRILNDKLLEELKKIK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_CHESB
Sequence: MPKRVLQGTVVSDKNDKTVVVRVERRFAHPLLKKTVRRSKRYKAHDENNMCKVGDVVLIQETRPISKDKCWVVVNENQAQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: DNLJ_LACLA
Sequence: MNIESKIKELTEKLNQYAYEYYTLDEPSVEDSEYDRLYQELVKLEAENPQLTRADSPTHRTGGVILDGFVKFRHPYNLYSLGDVFSREELAVWEERVRKEIANPEYICELKIDGLSLSLYYENGLLMTAATRGDGTTGENITENVKRIKDVPLKLKEAIDIVVRGEAYLPRKNFAKLNKERELEGATPFANPRNAAAGTLRQLDTKIVAKRGLATFLYQEASPATNDTQEEVLEYFEELGFQVNPERKFARNMDEIWEFIEEATRLRDELPYDIDGVVVKVNNLAEQEELGFTVKAPRWAIAYKFPAEQAETEILSVDWTVGRTGVVTPTANMTPVLLAQTTVARATLHNVDYIEEKDIRIGDHVLIYKAGDIIPKVGKVLLDKRPEGLEGLEIPTKCPECGSELIHFEDEVALRCVNPLCPAQIREKLIHFASRDAMNIVGLGPSVISQLFDKKLVADVADLYQLTIEDLLTLDKVKETLAQKIVSAIAQSRENSAEKLLFGLGIRHVGGKAAKLLLERFANLRALSKATEEEISEIPSLGGVIATAVVSYFETDGAKILLDELENAGVNFDYLGAVNIEGILSGKTVVLTGKLTTLKRSEAKEKLEALGANVSGSVSKKTDLVVAGEEAGSKLTKAQDLGIEIWSEQDLLDL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: BPPCD_BOTCO
Sequence: QNWPHPPMPPAP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 12d, BPP-12d.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: CUTC_ALIFM
Sequence: MSIQIEVCIDNLESLHNAITGGADRIELCSSLALGGLTPSFGFMKKAAEISPIPVYAMIRPRQGDFLYDNDDIAAMISDIQAAKLAGLQGVVFGVLKANGDIDMPLSARLMKIANDNDLGVTFHRAIDQCSNYKKAIENIAELGCERILTSGLAANAYDGINVLADMVKLANGRFDILAGAGVTAENAKEIIEKTGVKEVHLSGKSTRPSKMKLILDGVKMGAGDLDDFIVPVTDAKKIDAVKQRIK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_NITMU
Sequence: MASLKQQTPRIGFVSLGCPKALVDSEQILTQLRAEGYETSSTYEDADLVVVNTCGFIDSAVEESLDAIGEALAENGKVIVTGCLGAKEGGDVVKQAHPQVLAVTGPHALPEVMAAVHMHLPQPHDPYTSLIPPQGIKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIHQVMEEAENLVNAGVRELLVISQDTSAYGVDVKYRTGFWQGRPLKTRMTDLARSLGELGVWVRLHYVYPYPHVDEVIPLMAEGKILPYLDVPFQHASPRILKAMKRPANSENNLSRIRRWREVCPDITLRSTFIVGFPGETEAEFEQLLEFLEEAQLDRVGCFAYSPVEGAAANALPDPVPEEVKEERRACFMAIQEKISAERLARKIGKRMIVLIDDVSKNKAVARSTADAPEIDGLVYIGKAKNVKPGEFIEVEIIRSDPHDLHARQVSDNRT
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_MARMS
Sequence: MAKVSMIQREAKRTKLVAKFAEKRAALKAIISDVNASDDEKWEATLKLQALPRDSSSSRQRNRCQITGRPHGVYRRFGLSRIKLREAAMRGDVPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RL13_HELPH
Sequence: MTKTAKVNDIVRDWVVLDAKDKVFGRLITEIAVLLRGKHRPFYTPNVDCGDFVVVINANKVKFSGMKLEDKEYFTHSGYFGSTKSKTLQEMLEKTPEKLYHLAVRGMLPKTKLGKAMIKKLKVYRDDKHPHTAQTSKKDAK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RIC8A_CHICK
Sequence: MELRTVVATVESGEQDAVLKVLQIYNQEKSQCFTFDDEEREERKKMAQLLIKFLERELQPSCQVTCLESIRILSRDKYCLEPFTTEEGLKTLSRHAGIDYSEELIREVPDLEVILESLKCLCNIVFSSPRAQELTAEARLVVGLTKRIKLYNERSLPHEVKFFDLRLLFLLTALRVDIRQQLAQELRGISLMTDTLELTLGVKWMDPYEVATEEGLLPPLPRQETERAMEILKVLFNITFDSSKREVDEEDAALYRHLGALLRHCLMISADGEDRTEEFHSHTVNLLGNLPLKCLDVLLTPKVRPGSLEYMGVNMDAVNILLDFLERRLDRGHKLKESLTPVLNLLTESARVHRQTRKFLKAKVLPPLRDVKNRPEVGNSLRNKLVRLMTHIDTDVKHCAAEFLFVLCKESVSRFVKYTGYGNAAGLLAARGLMAGGREEGEYSEDEDTDTEEYKEAKPNINPVTGRVEEKLPNPMEGMTEEQKEYEAMKLVNMFDKLSREQVIQPMGITPSGNLAPMENAIRDMADERSSSDSDLGLD
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins.  Able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP.  Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).
What are the official names of this protein?
Synembryn-A, Protein Ric-8A.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: MOBA_METAC
Sequence: MSGKTELKPGRTKSRSAIVLAGGRGRRMGMVEKALLEFEGKTILERLLENLFRVVDEVILSVRDIPQKEKLLPVLEKFPDREIRFCFDSREDAGPLEGIRAGLLESRSEYSFVCAGDMPFVNSEIVDLLFEKANGHDAALPRWEEDRMYEPLHAVYSRKMLLEIEKTFEGERNSVLTPVFAMKDVVFVEVSEIRGIDPELRTFANINTVEDIESMIGSVVGKVEL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI39_MOUSE
Sequence: MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQTVKRKIRDESLCSQHHEPLSLFCYEDQEAVCLICAISHTHRPHTVVPMDDATQEYKEKLQKCLEPLEQKLQEITCCKASEEKKPGELKRLVESRRQQILKEFEELHRRLDEEQQTLLSRLEEEEQDILQRLRENAAHLGDRRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPQRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE
What is the function of this protein?
E3 ubiquitin-protein ligase (By similarity).  May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1 (By similarity).  Regulates the G1/S transition of the cell cycle and DNA damage-induced G2 arrest by stabilizing CDKN1A/p21 (By similarity).  Positively regulates CDKN1A/p21 stability by competing with DTL for CDKN1A/p21 binding, therefore disrupting DCX(DTL) E3 ubiquitin ligase complex-mediated CDKN1A/p21 ubiquitination and degradation (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM39, RING finger protein 23, RING-type E3 ubiquitin transferase TRIM39, Testis-abundant finger protein, Tripartite motif-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion. Nucleus. Note=Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when colocalized with MOAP1. Colocalizes with CDKN1A in the nucleus.
Protein: CBPA5_HUMAN
Sequence: MQGTPGGGTRPGPSPVDRRTLLVFSFILAAALGQMNFTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPFSELKDIKAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQSILVLKFSTGGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAKDAVEALYKVHGIEYIFGSISTTLYVASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNHPY
What are the official names of this protein?
Carboxypeptidase A5.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_LACDB
Sequence: MDNVMAQLESLEVRYEEIQEMMADPEVIADTKRYMEITKEEADMREVVQKFRKFKADKEEIAGNKEIIADGSDPELVEMAKMENSELEDEISQLEDEIKILMLPKDPNDDKDIIMEIRGAAGGDEASLFAGDLLRMYEKYAENQGWNVSIVDSEQTEVGGYKRVAIMITGNKVYSKLKYENGAHRVQRIPVTESAGRVHTSTATVAVMPEYEQVDIDLDPKEIRVDVYRSSGAGGQHINKTSSAVRMTHLPTGIVVAMQDQRSQQQNRAKAMEILKSRVYDYYESQNRDKYDAKRKNAVGTGDRSERIRTYNYPQNRVTDHRIGLTLNKLDRIMNGELDEVIDALTVYYQTKQLEELAENA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYTB_GORGO
Sequence: MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF
What is the function of this protein?
This is an intracellular thiol proteinase inhibitor.  Tightly binding reversible inhibitor of cathepsins L, H and B (By similarity).
What are the official names of this protein?
Cystatin-B, Stefin-B.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FEOC_YERPY
Sequence: MASLLQLRDAIALNGSAEASQLSRQLAIPLPLVNAMLEKLTAMGKIERIELDHSGCLTGSCKSCPEGHQHCNTVIYQLKEPHAHQ
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: COAE_SYNC1
Sequence: MLVLGLTGGIGSGKSIVAEMFRTLGAKVVSADDLARMIVQPGSPTLARIARRFGAEVLCEGGALNRAWLAKKIFSDPQARLDLDRITHPAIAELARRRFAALAQASATLVVYDAPLLFEAGADTQVDAVVVVSVAEEVQLQRLMLRDGLDEQAARSRMDSQMPLDEKLARADYVIDNNGSLEQTRDQVVALMARLVPGMKGPDPHASGSAG
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_HAHCH
Sequence: MIEADRIISPNATLQEDSQDRAIRPKRLEDYVGQPQVREQMEIFINAARGRQEALDHTLIFGPPGLGKTTLANIIANEMDVSIKTTSGPVLEKAGDLAALLTNLEPKDVLFIDEIHRLSAAVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGLLTSPLRDRFGIVQRLEFYSVEDLRHIVARSASLLGVSIDDGGAHEIARRSRGTPRIANRLLRRVRDYAEVKADGAITNEVADKALNMLNVDLHGFDHMDRRLLLAVMEKFDGGPVGVESLAAAIGEEKGTIEDVVEPYLIQQGFLMRTPRGRVATQAAYNHFGLTMPE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: BAMB_SALTY
Sequence: MQLRKLLLPGLLSVTLLSGCSLFSGEEDVVKMSPLPQVENQFTPTTVWSTSVGNGIGEFYSNLHPVMVDNVVYAADRAGVVKALNADDGKEIWSVNLGEKDGWFSRSSALLSGGVTVAGGHVYIGSEKAEVYALNTSDGTTAWQTKVAGEALSRPVVSDGIVLIHTSNGQLQALNQADGAIKWTVNLDMPSLSLRGESAPATAFGAAIVGGDNGRVSAVLMQQGQMIWQQRISQATGPTEIDRLSDVDTTPVVVNGVVYALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGDRIYLVDQNDRVLALTTDGGVTLWTQSDLLHRLLTSPVLYNGDLVVGDSEGYLHWINVDDGRFVAQQKVDSSGFLTEPTVADGKLLIQAKDGTVYAITR
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
What are the official names of this protein?
Outer membrane protein assembly factor BamB.
What is the protein family that this protein belongs to?
Belongs to the BamB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: S2544_MOUSE
Sequence: MEDKRNIQIIEWEHLDKKKFYVFGVAMTMMIRVSVYPFTLIRTRLQVQKGKSLYHGTFDAFVKILRADGVAGLYRGFLVNTFTLISGQCYVTTYELTRKFVADYSQSNTVKSLVAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVHGNLEGQGVIAFGQTKDIIRQILRADGLRGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSRLCPQECPHIVFQAISGPLAAATASILTNPMDVIRTRVQVEGKSSIVLTFRQLMAEEGPWGLMKGLSARIISATPSTIVIVVGYESLKKLSLRPELVDSRHW
What is the function of this protein?
Mitochondrial solute transporter which transports branched-chain amino acid (BCAA; valine, leucine and isoleucine) into mitochondria in brown adipose tissue (BAT) (PubMed:31435015).  BAT is involved in BCAA catabolism and actively utilizes BCAA in the mitochondria for thermogenesis (PubMed:31435015).
What are the official names of this protein?
Solute carrier family 25 member 44.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: YGDR_ECOLI
Sequence: MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDDDTGLVSYHDQQGNAMQINRDDVSQIIER
What are the official names of this protein?
Uncharacterized lipoprotein YgdR.
What is the protein family that this protein belongs to?
To E.coli YgdI.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: DXR_GEOKA
Sequence: MKYISILGASGSIGTQTLDVIRAHPDEFRLAAASVGKNIEAARRLIAEFSPSLVAVADRDAYKVLYREYRGRTTIVYGEEGLIEAAVCPQADVVVTAVVGSVGLVPTLKAIEAGKAIALANKETLVVAGHLVMAAAKRRGVPLLPVDSEHSAIFQCLQGERMEHVDKLILTASGGSFRDKTRRELAHVTVEEALCHPNWSMGAKITIDSATMMNKGFEVIEAHWLFGLPYERIEVVLHRESIIHSLVQFRDTSVLAQLGTPDMRVPIQYALAYPKRLPLPSAKPLDFISLGALHFAPVDFDRYRCLRLAYEAGKRGGSLPTVLNAANEEAVAAFLAGRIPFLAIEEWIERALERHRPVSNPQLEDIREIDADARAYVRSLLS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: EFM5_DROME
Sequence: MDDDISLPADTLAILNEFLLERSKREAEEENQIANKTGKDAQFEEDWQLSQFWYSTETKHALRDVVRKLLAERTEDSGDFSIALLSCPSLYKDIREIHDTVHIFEFDKRFEAYGTDFVHYDLNCVGSNPDYLKEHHQQYDLIVADPPFLSQECIAKTCEIITRLQRNQKESKVILCSGEVVEPWLTARLPVLKCSFRPEHERNLGNKFVSYANFNLDEYIENK
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.
What are the official names of this protein?
Protein-lysine N-methyltransferase CG9154.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8948_DICDI
Sequence: MTSPIPTPTKFDDKFGSISKSYKNFRPTYNDELYSIIDSHCDEKRDLAIDIGAGSGQATVRLAKYFKKVIGFEPSQGQIENAEKTDNVEYRLSAAEKIDLPSGSVDLITVAQAAHWFNLPVFYEESKRLLRENGSLIIWSYGLMKITNNNDAQVVHEKHYYETIGDQYWAPERKYIDDEYVDIKPSFENTTRKTISLPKSMSINDMIGYYSSWSGYAAFIKAGNKDVLPEIKETLLKAYKTTDGDSKLIDVNFPVYMILSKKE
What are the official names of this protein?
Putative methyltransferase DDB_G0268948.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.