PharMolix/UniProtQA huggingface dataset:
Protein: PURA_CITK8
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKGLEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFAVKLKEVMEYHNFQLVNFYKVEAVDYQKVLDDVMAIADILTSMVVDVSDLLDQARKRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGIIKAYSTRVGAGPFPTELFDDTGEFLCKQGNEYGATTGRRRRTGWLDSVAVRRAVQINSLSGFCLTKLDVLDGLEEVKICVAYRMPDGREVTTTPLAADDWEGIEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_MAGMM
Sequence: MSDNKPSEGDNKLQLKAPRRIVLKKTVEGSSIKQNFAHGRSKSVAVEVRRKKTFLKPGSKEGGFLIDQEKPEEIEEKKEAPKSPKRGEERHILRPLTPEEIEAKQKELEAKRQAEEEAARQKAEQEAARQKQEAEAARRKAEQEAARQKQEAEAARRKAEEEAARAAAAAPAAPVAAPAEAAPAVPVAVAEPVVVAQPAPEAPAPVVEEEMVEAKPLPAAAPAAPSAPVRLLHQPVEEEPKRKLSKAQREEMARRKTEDLVSKRLNQLEELREQKRKEDARKEAEVALAKKEKPVVAATAAAAAEVVAGRTPREDSAGEPFSAGRRKNKKYQDNEDRLQQPRGKSRRRKPFKSEMQAPAPVYREVTIPETITVGELANRMAVKSSEVIKLLFAQGMLVTINQTLDQDTAVLVVEEMGHKPKSVSESAAIEAELDAGEDAAEDMETRPPVITVMGHVDHGKTSLLDAIRSTDVTSREHGGITQHIGAYQVTLASGDKITFLDTPGHSAFTAMRARGAQVTDIVVLVVAADDGVMPQTVEAINHAKSAKVPIVVAVNKIDKPGSNPDRVMQQLSDHGLVPEAWGGDTIFVHVSAKSGEGISTLEEMLLLQAEMLNLQSNPTKKRARGTIIEANLDRGRGAVATCLVQNGTLRVGDICVVGNEWCRVRALNDDRGNQVSEASPSMPVEIIGLSGVPQAGDDLVAVNDERRAREIAQFRQQKDKEAIQAKQQPATRLEDMFEHIEQGEVEELNVVLKADVQGSVEAVAEALRKIKHEQIEVRVIHTGVGGINESDVMLAVASGAITVGFNVRADAKARDLAKREQIDLRFYNVIYDLVDDISLALEGRLAPTVREKVLGHAQVREVFRITKIGNVCGCLVTDGIIQRNGKLRILRQNVVVYEGPVSALKRFKDDVKEVREGFECGISIEKFNDVKVDDVLECYVEEQVKQTLS
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSSGP_EBOZ5
Sequence: MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYTSGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKKPH
What are the official names of this protein?
Super small secreted glycoprotein, SsGP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
Secreted.
Protein: LARC_NOCSJ
Sequence: MTTAWVDASAGASGDMLLGALVGAGVPVAVLQAAVDAVAPEPVTLRVEHVRRGGLAATRCHVEVTDTARHRTWRDVRTLLAAADLADDVRGLALRVFERLATAEATVHGTSPDDVHFHEVGALDAIADVTGVVAGFVHLGATAVTVSPVAVGSGSVSTAHGLLPVPPPAVAELLRGVPSYAGAATMETCTPTGAALLTTLATAYGPQPAMSVDTIGVGAGGRDPEGHPNVLRLFVGVPADAGGGPLLLECNVDDLDPRVWPAVIAALLEAGASDAWLTPILMKKGRPAHTLSALVDAGRAAGVRAAIFRQTSTIGLREQPLTKHALEREIVAVDVDGQRIAVKLARHDGAVVNAQPEYDDVARAAADLDRPVADVLAEAVARGRAFLTPGDKI
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor.  Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, P2TMN nickel insertion protein, Nickel-pincer cofactor biosynthesis protein LarC.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: BAF1_CAEEL
Sequence: MSTSVKHREFVGEPMGDKEVTCIAGIGPTYGTKLTDAGFDKAYVLFGQYLLLKKDEDLFIEWLKETAGVTANHAKTAFNCLNEWADQFM
What is the function of this protein?
DNA-binding protein which plays an essential role in nuclear envelope formation (PubMed:17170708).  Required for normal chromosome segregation during mitosis (PubMed:12684533).  Associates with the nuclear lamina via its interaction with LEM domain containing proteins emr-1 and lem-2 (PubMed:12684533).  In association with lem-3, plays a role in radiation-induced DNA damage repair response (PubMed:22383942).
What are the official names of this protein?
Barrier-to-autointegration factor 1.
What is the protein family that this protein belongs to?
Belongs to the BAF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPB_ACIBT
Sequence: MSSGRIIQIIGAVIDVEFERTSVPKIYDALQVDGTETTLEVQQQLGDGVVRTIAMGSTEGLKRGLTVTSTNAPISVPVGTATLGRIMDVLGRPIDEAGPVATEERLPIHRQAPSYAEQAASTDLLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEYFRDEKDENGKGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKSGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASSGIYPAIDPLDSTSRQLDPLVVGQEHYEIARAVQNVLQRYKELKDIIAILGMDELAEEDKLVVYRARKIQRFFSQPFHVAEVFTGAPGKLVPLKETIRGFKGLLAGEYDHIPEQAFYMVGGIDEVIAKAEKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RR18_PHYPA
Sequence: MKQAINKSKRSSRRRLPPIRSGEIIDYKNINLLRRFISEQGKILSRRMNRLTSKQQRLMTIAIKRARVLALLPFLNNEN
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PANB_KORVE
Sequence: MSIATGDFRSKVTSSTLLDKKSKHDPITCLTAYDYSTARLVDEAGIDMILVGDSLAQTMLGYENTLPVTMDEMLHHTRAVRRAVRHAFLIADMPYASYHVGGRESVRNAARFIKEGGAEAVKIEGGENRAALIDRLLDAEVPVVGHIGLTPQSVHRMGGYKVQGKTIRDIEQLMRDATALDRAGVVALVLEGIPREVAAMITAEVETPTIGIGAGPDCDGQVLVFHDILNLTFAPPAKFVRRYADAAELITGAVKAFRDDVKTGSYPSDDESYHLPKEAQATLEMVQNRKHAMRK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAT7_FUSBL
Sequence: MLRLGASVGVHQGSRILFSDFADGGQMWTGNGPREYRLDVTFPEPFTRTPAVTVGLSMWDMDHKTNSRMDIGAENITPQGFQIVFKTWGDTRIARVRADWLAIGSVRDDEDWEIE
What are the official names of this protein?
ATP synthase subunits region ORF 7.
Protein: ARGJ_RHIME
Sequence: MSGSVSPLAPKTFAEMPALRGVRMATAAAGIKYKNRTDVLMMLFDRPASVAGVFTRSKCPSAPVDHCRQNLPGGIARAVVVNSGNANAFTGKKGREATRLTAEAAAKAVGCSEAEVFLASTGVIGEPLDATKFAGVLDKLAASATQDFWFEAAKAIMTTDTYPKVATRSAEIGGVKVAINGIAKGAGMIAPDMATMLSFVVTDADIAPAALQALLQAGVEPTFNSVTVDSDTSTSDTLMLFATGAAAGDGQAKVEDAADPRLDGFRAALDDLLRDLALQVVRDGEGARKMVEVTVEGAENDAAAKRIALSIANSPLVKTAVAGEDANWGRVVMAVGKSGEMAERDRLAIWFGDIRVAVEGERDPAYSEAAATAVMQGETIPIRVDIGLGSGRATVYTCDLTKEYVEINGDYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP83_BOMMO
Sequence: MPEEMETQPAEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELYIKIIPNKNEGTLTIIDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADRVTVHSKHNDDEQYVWESSAGGSFTVRPDSGEPLGRGTKIVLHVKEDLAEFMEEHKIKEIVKKHSQFIGYPIKLMVEKEREKELSDDEAEEEKKEEEDEKPKIEDVGEDEDEDKKDTKKKKKTIKEKYTEDEELNKTKPIWTRNADDITQDEYGDFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKRKNNIKLYVRRVFIMDNCEDLIPEYLNFIRGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEELAEDKENYKKYYEQFSKNLKLGIHEDSQNRAKLSELLRYHTSASGDEACSLKEYVSRMKENQKHIYYITGENRDQVANSSFVERVKKRGYEVVYMTEPIDEYVVQQMREYDGKTLVSVTKEGLELPEDEEEKKKREEDKVKFEGLCKVMKNILDNKVEKVVVSNRLVESPCCIVTAQYGWSANMERIMKAQALRDTSTMGYMAAKKHLEINPDHSIVETLRQKAEADKNDKAVKDLVILLYETALLSSGFTLDEPQVHASRIYRMIKLGLGIDEDEPIQVEEPASGDVPPLEGDADDASRMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).  Required for piRNA biogenesis by facilitating loading of piRNAs into PIWI proteins.
What are the official names of this protein?
Heat shock protein 83, BmHSP90.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_METSB
Sequence: MTKPRTLYDKIWDEHLVHESADGSSLLYIDRHLVHEVTSPQAFEGLRLTGRTVRAPQKTLAVVDHNVPTTDRSKGIADHESRTQVEQLAINAREFGVEYFNELDPRQGVVHIIGPEQGFTLPGATIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQSKAKNMRVIVDGQPSEGVSAKDIVLAIIGEIGTAGGTGHVIEYAGEAIRALSMEGRMTVCNMSIEGGARAGLIAPDDKTFAFLKDRPKSPKGKAWDEAVAHWRTLHSDEGAHFDKEVRLDAASLPPIVTWGTSPEDVATINGEVPRVESAMSEAKRVSIARALDYMGLKGGEKITDISIDRVFIGSCTNGRLEDLRAAAKILAGKHIAAHVNGMVVPGSGLVKQQAEAEGLDVVFREAGFEWREPGCSMCLAMNPDRLEPGERCASTSNRNFEGRQGFKGRTHLVSPAMAAAAGVAGHFVDIRTWR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: COXX_RHOPS
Sequence: MSVIDTNQIDLAAPRISEAGVADYVALLKPRVMSLVVFTALVGMLLAPGDFHPVLAVTAMLCIAVGGGAAGALNMWYENDIDALMTRTANRPIPRGRVTRPEALTFGMTLSFFSVVTLGVLVNWIAAALLAFTIFFYVVIYTMWLKRSTAQNIVIGGAAGALPPVVAWAAVTGSLAVEPLLLFAIIFFWTPPHFWALALFRNDDYARAGVPMLPVVAGPDHTRLQILLYTIVLVAVAAAPWPLGYFDAVYGIASLALGGWMLVLAIRVYRHRSGSAALRATRNLFKFSILYLFALFSILLIEVVAKAVWQLFA
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPR_YERPS
Sequence: MTDEKQVSDSLNRQTAGNPYSAADPALSAEDNQHWLSFVALLQNAITQDLHLPLLQLMLTPDERTALGTRVRIIEELMRGELSQRELKSQLGAGIATITRGSNSLKTAPPQLKSWLEAQLLANKR
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y847_TREPA
Sequence: MLNLGQVKVLEEKVAKAVHLVQMLKEENAALRAEIDGRGKRITELEQLVLXFQDDQTKIEEGILKALNHLSTFEDSAYGEALTQHAAKVLENREHAGLSEELTSRTQMEIF
What are the official names of this protein?
Uncharacterized protein TP_0847.
Protein: FON2_ORYSJ
Sequence: MGRLFLCLVVAWCWVALLLVAPVHGRVGLPGEFSGDQRPVPATSFDLVTEPKTKQPRGVKGTRRPSWSSWSSTASRSSPPPGRGAPSAAAAAELRSVPAGPDPMHHHGSPRRPEHARSTGRP
What is the function of this protein?
Probable extracellular signal that regulates meristem maintenance.  May function as a putative ligand for a receptor complex including FON1.  Regulates the size of the floral meristem and the number of floral organs.
What are the official names of this protein?
Protein FLORAL ORGAN NUMBER2, OsFON2, CLAVATA3-like protein, Protein FLORAL ORGAN NUMBER4.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_TOBAC
Sequence: MTLNLSVLTPNRIVWDSEVEEIVLSTNSGQIGILPNHAPIATAVDIGILRIRLNDQWLTMALMGGFARIGNNEITVLVNDAEKGSDIDPQEAQQTLELAEANVKKAEGRRQKIEANLALRRARTRVEAINPIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: NU4M_CERGO
Sequence: PIAGSMVLAAVLLKLGGYGIIRMMQTLPTTKTDMFLPFIVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGFHNILPMTTTWWLLANLMNIATPPTLNFTSELLIMSTLFNWCPTTIILLGLSMLITASYSLHMFLSTQMGPTLLNNQTEPMHSREHLLMALHLVPLMMISMKPELII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TSAD_RHOP2
Sequence: MTSEQTLLVLGIETTCDETAAAVVERRADGSGRILSNIVRSQTDEHAPFGGVVPEIAARAHVDLLDGIVARAMREAGTGFPELSGVAAAAGPGLIGGVIVGLTTAKAIALVHNTPLIAVNHLEAHALTPRLTDATEFPYCLFLASGGHTQIVAVRGVGDYVRLGTTVDDAIGEAFDKIAKMLGLPYPGGPQVERAAASGDAVRFAFPRPMLGRPDANFSLSGLKTAVRNEASRLTPLEPQDINDLCAGFQAAVLDSMADRLTSGLRLFRERFGAPKALVAAGGVAANQAIRRALREVAAKAQTTLIVPPPALCTDNGAMIAWAGAERLALGLTDSMDAAPRARWLLDANATAPGKFANTRAGF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB6_CHLRE
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCIGGITFTCFLVQVATGFAMTFYYRPTVAEAFASVQYIMTDVNFGWLIRSIHRWSASMMVLMMVLHVFRVYLTGGFKRPRELTWVTGVIMAVCTVSFGVTGYSLPWDQVGYWAVKIVTGVPDAIPGVGGFIVELLRGGVGVGQATLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: PG137_VACCW
Sequence: MTTVPVTDIQNDLITEFSEDNYPSNKNYEITLRQMSILTHVNNVVDREHNAAVVSSPEEISSQLNEDLFPDDDSPATIIERVQPHTTIIDDTPPPTFRRELLISEQRQQREKRFNITVSKNAEAIMESRSMITSMPTQTPSLGVVYDKDKRIQMLEDEVVNLRNQRSNTKSSDNLDNFTKILFGKTPYKSTEVNKRIAIVNYANLNGSPLSVEDLDVCSEDEIDRIYKTIKQYHESRKQKIIVTNVIIIVINIIEQALLKLGFEEIKGLSTDITSEIIDVEIGDDCDAVASKLGIGNSPVLNIVLFILKIFVKRIKII
What is the function of this protein?
Required for viral crescent formation early during virus morphogenesis.
What are the official names of this protein?
Protein OPG137.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG137 family.
Protein: PTH_PSEA7
Sequence: MTAVQLIVGLGNPGPEYDQTRHNAGALFVERLAHAQGISLVAERKYFGLVGKFSHQGKDVRLLIPTTYMNRSGQSVAALAGFFRIPPDAILVAHDELDMPPGVAKLKTGGGHGGHNGLRDIIAQLGNQNSFHRLRLGIGHPGHSSLVSGYVLGRAPRSEQELLDTSIDFALGVLPEMLAGDWTRAMQKLHSQKA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_CORDI
Sequence: MTDFSRADGRAVDQMRTVKITRGFTSNPAGSVLVEFGNTRVMCTASVELGVPRFKRDSGEGWLTAEYAMLPAATAERNARESMRGKVKGRTHEISRLIGRSLRAAVDLDELGENTINIDCDVLQADGGTRTASITGAYVALADAIAVLKEQGVVPGNPLKAAVAAVSVGVIDGQVCLDLPYEEDSRADVDMNVIMQGDRFVEIQGTGEHNTFDRDELAVILDFAQKGCQELFAAQKAALEQ
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: ODFP2_HUMAN
Sequence: MSASSSGGSPRFPSCGKNGVTSLTQKKVLRAPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARPVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERMKEEKDFTILQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYSTFLTSSPIRSRSPPA
What is the function of this protein?
Seems to be a major component of sperm tail outer dense fibers (ODF).  ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.  May have a modulating influence on sperm motility.  Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles.  Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes.  Required for the formation and/or maintenance of normal CETN1 assembly.
What are the official names of this protein?
Outer dense fiber protein 2, Cenexin, Outer dense fiber of sperm tails protein 2.
What is the protein family that this protein belongs to?
Belongs to the ODF2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell projection, cilium, flagellum. Note=Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
Protein: Y3338_CLOB6
Sequence: MSGHSKWHNIQAKKGKVDAKRGKIFTKIGKEIVVAVKQGGPSADSNPRLRDVIAKAKANNMPNDTIERSIKKASGELNAVDYETITYEGYGPAGIAVLVDVLTDNKNRSAGNVRYAFTKQGGNMGSTGCVSFMFQSKGQIVIEKKDGLDEDELMMMALDAGAEDFESEDEVYVVTTSQEDFGTVREALEAEGLEFLEAEIKMVPDTYTAIDEDTATKFQKMLDVLEDDDDVQNVYHNAEFPEGWEE
What are the official names of this protein?
Probable transcriptional regulatory protein CLJ_B3338.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHLB_PHOPR
Sequence: MKTTHITEQKFADLGLEPTVLEGLDAQGFHYCTPIQALALPVVLTGQDIAGQAQTGTGKTLAFLTATFNYLLLNPASDERKTNQPRAIIMAPTRELAIQIYNDAAPLLASTGLKAGLAYGGEAYEKQQKVFAEGVDILIGTCGRIIDFYKQRVIDLASIQVVVLDEADRMFDLGFIKDIRFLFRRMPAPKARLNMLFSATLSYRVKELAFEHMNSPESVVVEPNQKTGHLIQEELFYPSNQEKMRLLQTLIEEEWPDRAIIFANTKHRCEDIWGHLAADNHRVGLLNGDVPQKKRVRILEQFTQGDIDILVATDVAARGLHIPQVTHVYNYDLPDDAEDYVHRIGRTGRAGESGSSISFACEEYAINLPAIETYIEHPIPLSKYNSEALLDELPAPLRLQRTPRQGGNRRPNGNRQGQGQSRPRNNNRRHPQSQKQQ
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS28_HUMAN
Sequence: MDTSRVQPIKLARVTKVLGRTGSQGQCTQVRVEFMDDTSRSIIRNVKGPVREGDVLTLLESEREARRLR
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:23636399, PubMed:25901680, PubMed:25957688).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:25901680, PubMed:25957688).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797).
What are the official names of this protein?
40S ribosomal protein S28, Small ribosomal subunit protein eS28.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).