PharMolix/UniProtQA huggingface dataset:
Protein: LEUC_ALIB4
Sequence: MGQTITEKIFSEHAGKKVYAGEIVRSPIDMVIGNDITTPISIRAFEEGGFEKLANPDGFAIVLDHFIPAKDIASANQAKISRDFALKHNLKNFFDEKDMGIEHALLPEKGLVIPGDVIIGADSHTCTHGALGAFSTGMGSTDISFGMITGGNWFKVPESIKVIFKGKPAPFVTGKDLILEIIRILGVDGALYKALEFTGDTIQYLSMDDRFSLCNMAIEAGAKNGIVAYDEITKEFLDKVGEANGGLRAEPKIHYSDEDANYCQVIEIDVAKLEPVIAYPYLPSNGHSVSQAVSDNIKVDQVFIGSCTNGRLSDFKIAAEILAGQKVARHVRLILTPGTQKILREATKLGYIDTLVDAGAVVSNPTCGACLGGYMGILGDNEVCISTTNRNFVGRMGSRSSKIYLANSAVAAASAISGYITDPRSL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: COR1A_MACFA
Sequence: MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLVLPLREPVVTLEGHTKRVGIVAWHPTAQNVLLSAGCDNVIMVWDVGTGAAVLTLGPEVHPDTIYSVDWSRDGGLICTSCRDKRVRIIEPRKCTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVALWGTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPEASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK
What is the function of this protein?
May be a crucial component of the cytoskeleton of highly motile cells, functioning both in the invagination of large pieces of plasma membrane, as well as in forming protrusions of the plasma membrane involved in cell locomotion.
What are the official names of this protein?
Coronin-1A, Coronin-like protein A, Clipin-A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cytoplasmic vesicle, phagosome membrane.
Protein: PAX1_CHICK
Sequence: EHTYGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPNVVKHIRDYKQGDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGSLSQPGGPYDGGKQPPPQPALPYNPLYQYPYPGPMDPRAAKMGADPPGPVPAAHVGLPRSWPSAHSVTNILG
What is the function of this protein?
This protein is a transcriptional activator.  It may play a role in the formation of segmented structures of the embryo.  May play an important role in the normal development of the vertebral column (By similarity).
What are the official names of this protein?
Paired box protein Pax-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: NLP10_PLAVT
Sequence: MKLPTFLIGFVALLVTSNGSARYVYREDPDDSADPPNPGALHANPILIDVDDVQPFPQPRAITDSQKSALVYKPRLYIKSGCHPYPAVQANGSLSDGLQWKNFLRSPCPGSPKGSQVYSRSDWYEGKWAIMYAWYLPRALDRVTWLVNGHRHYWLWVVVWTDSPDPKTSTLLATSMPGVANNIHKYYPPKSKYVIREKTLKVKSYQNHILFIKHGLELTDRAGDFQDLVTWEQMTDEARAALSTFHRPEHAANPPLQDKRFYEVLEKAYPFDR
What is the function of this protein?
Secreted effector that acts as a pathogen-associated molecular pattern (PAMP) recognized by the plant immune system (PubMed:35152834).  Seems not to induce necrosis in Nicotiana benthamiana leaves but significantly improves disease resistance of Arabidopsis thaliana to Hyaloperonospora arabidopsidis and causes an inhibition of plant growth which is typically associated with enhanced immunity when over-expressed in Arabidopsis (PubMed:35152834).
What are the official names of this protein?
NLP effector protein 10, Nep1-like protein 10.
What is the protein family that this protein belongs to?
Belongs to the Necrosis inducing protein (NPP1) family.
Protein: FOLD1_BORPE
Sequence: MTARIIDGAALSQRIREEVAQRVQALTAKGVRPGLAVVLVGDDPASQVYVRNKVAACEKAGLHSVKEQYPADLTEAQLLERIDALNRDPSIHGILVQLPLPRHMDAHKVIEAIAAEKDVDGFHISNAGLLMTGQPLFRPCTPYGVMKMLESEGVALRGAEAVIVGASNIVGKPMAMLLLQAGATITICNSKTRDLGAQTRRADVLVVATGKPGMIDGSMIKPGAVVIDVGINRGADGKLCGDVDMASAREVAGAISPVPGGVGPMTIAMLLVNTVEAAERAAA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 1.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PIMT_DICT6
Sequence: MDFKKFDTPEYEHKRRKLVEILKDEGIKSQKVLNAILKIPRHMFVPQEYLSLSYENEALPIGYGQTISQPYIVALMTEALNLQGNEKVLEIGTGSGYQTAILAELALEIYTVERIKELLEEAKKRLRVLGYNNVYFKLGDGTLGWEEFAPYDRIIVTAASYDIPEPLKEQLKDGGIMVIPIGGRDFQYLYRITKKGDNFYRENLGGVRFVPLKGEYGWKD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_CHLL2
Sequence: MPTLKDIRVRIKGIKSTQQVTKAMKMVAAAKLRRAQERAIMARPYAGKLKEMLGSLSAKVDTSLNPLLSSRQDVKKVLVILIAADRGLCGAFNTNIIKLAQKVVTEDYAAQYKNGGVSMICAGSRGFDFFRKRGFSIVKGYPSVFQNLDFSVAKEIAETASGMYLRGEADKVIVVYNEFKSVLAPVLKAEDLLPIAAENAGKDNSGDYIYEPSPAVIIDELVPKHLSTQVWRMMLESNAAEQAARMTAMDSATENAKELLRTLNISYNRARQAAITKELSEIVAGADALKN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL5_LEPBJ
Sequence: MAARLRTKYKKEIVPELNKKFKFESIMQVPRLEKIVLNVGMGEAHTNPKALEAAVEELALITGQRPVKTKAKKSIAGFKIREGMSLGCMVTLRGDYMYEFLDRLVNVALPRVRDFKGVNDKGFDGRGNYNMSIKEQIIFPEIKVDKINTLYGINMTFVTNSKSNEEALSLLAAFGMPYRNQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SAR1_MAGO7
Sequence: MWIINWFYDVLSSLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTLHPTSEELAIGNVRFTTFDLGGHQQARRLWKDYFPEVNGIVFLVDAKDHDRFPEAKAELDALLSMEELAKVPFVILGNKIDHPEAISEEELRHQLGLYQTTGKGKVPLEGIRPIEVFMCSVVMRQGYGEGIRWLSQYV
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y4429_CITK8
Sequence: MKRTKSIHHASFRKSWSARHLTPVALAVTAVFMLAGCEKSDETVSLYQNADDCSAANPGKNAECTTAFNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQSSGSFWMPLMAGYMMGRMMGGGAGFAQQPLFSSKNPASPAYGKYTDASGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSNRSMGG
What are the official names of this protein?
UPF0441 protein CKO_04429.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: BDS5D_HETCR
Sequence: GTPCDCYGYTGVYWFMLSRCPSGYGYNLSCHYFMGICCVKR
What is the function of this protein?
Toxin with different activities on acid-sensing ion channels 1 and 3 (PubMed:32326130).  It weakly and reversibly inhibits rat homomeric ASIC1 (isoform ASIC1a) (IC(50)=1. 25 uM), while it potentiates rat homomeric ASIC3 (EC(50)=1. 53 uM) (PubMed:29684594, PubMed:32326130).  ASIC1a current inhibition is not complete, and reaches a maximum of 86% inhibition (PubMed:32326130).  On ASIC3, this toxin does not activate the channel itself, but produces a remarkable potentiation of the transient current resulting from the acidic pulse (PubMed:32326130).  At the maximal applied concentration, it elicits responses that are twice as high as those produced by extracellular protons (PubMed:32326130).  Molecular modeling interaction with ASIC1a suggests that this peptide hinders the collapse of acidic pockets and stabilizes nonconducting channels state (PubMed:32326130).
What are the official names of this protein?
Pi-stichotoxin-Hcr5d, Pi-SHTX-Hcr5d, APETx-like peptide, Pi-AnmTX Hcr 1b-4, Hcr 1b-4.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: SP2AB_BACP2
Sequence: MRNEMNLTFSALSQNESFARVTVAAFIAQLDPTLDELTEIKTVVSEAVTNSIIHGYDGNPDGKVHIEVTLDDHVVYLTIRDEGMGITDLEEARQPLFTTKPDLERSGMGFTIMENFMDDVMIDSSPEMGTTIRLTKHLSKSKALCN
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: MRDA_ECOL6
Sequence: MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQIVRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTLDALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVLHGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKPYVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIHSGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAERLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAENPAVAAAEDH
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall.
What are the official names of this protein?
Peptidoglycan D,D-transpeptidase MrdA, Penicillin-binding protein 2, PBP-2.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. MrdA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ASNA_SHISS
Sequence: MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPFLPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRENVPSLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ2_YEAST
Sequence: MFIWQRKSILLGRSILGSGRVTVAGIIGSSRKRYTSSSSSSSSPSSKESAPVFTSKELEVARKERLDGLGPFVSRLPKKWIPYAELMRLEKPVGTWLLYLPCSWSILMGAMMQGATLSATAGMLGIFGVGALVMRGAGCTINDFLDRKLDQRVIRSVERPIASGRVSPRRALVFLGAQTLVGMGVLSLLPAQCWWLGLASLPIVFTYPLFKRFTYYPQAALSACFNWGALLGFPAMGVMSWPTMIPLYLSSYLWCMTYDTIYAHQDKKFDIKAGIKSTALAWGPRTKSIMKAMSASQIALLAVAGLNSGLLWGPGFIGGLGVFAYRLFSMIKKVDLDNPKNCWKYFNANINTGLYFTYALAVDYILRLFGFL
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
What are the official names of this protein?
4-hydroxybenzoate polyprenyltransferase, mitochondrial, 4-HB polyprenyltransferase, 4-hydroxybenzoate hexaprenyltransferase, Para-hydroxybenzoate--polyprenyltransferase, PHB:PPT, PHB:polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
Protein: AMPA_ECOLI
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Probably involved in the processing and regular turnover of intracellular proteins (PubMed:20067529).  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.  Required for plasmid ColE1 site-specific recombination but not in its aminopeptidase activity.  Could act as a structural component of the putative nucleoprotein complex in which the Xer recombination reaction takes place (PubMed:8057849).
What are the official names of this protein?
Cytosol aminopeptidase, Aminopeptidase A/I, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
Protein: PSD_BACC4
Sequence: MRRTLYRLMIELTNGRFTSYILRKFAQSRLSSIIIPSYAKVFQINQDEMEKGLKEYRTLHELFTRKLKEGKRSIDTDASSIVSPVDGVFADHGPIEDTKTFDIKGKRYSIVDMLGNEERATRYAGGTYMVIYLSPSHYHRIHSPLSGSVTERFVLGRKSYPVNAAGMEYGKEPLSKNYRSVTEVSSDGEHMALVKVGAMFVNSIELLHERDTVQKGEEMAYFTFGSTVVLLFEKDMIEVVQELKSGQELRLGEKIATRLAHK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYM_BRUME
Sequence: MSREKYYITTAIAYPNGKPHIGHAYELIATDAMARFQRLNGMDVYFLTGTDEHGIKMLQSARKEGITPRELADRNTSAFRRMAEVLNSSNDDYIRTSEERHYKASQVIWQAMVANGDIYKGGYAGWYSVRDEAYYGEEETEVRADGVRYGPQGTPVEWVEEESYFFRLSAYQDKLLDLYENNPGFIMPAERRNEIVSFVKSGLKDLSISRTTFDWGIPVPGDEKHVMYVWVDALTNYITALGYPDTTDERWAYWPANAHIIGKDISRFHAVYWPAFLMSAQLPLPKRVFAHGFLFNRGEKMSKSVGNVIDPFELVERYGLDQLRYFLMREVPFGQDGSYSHEAIVNRTNADLANDLGNLAQRSLSMIAKNCEGKVPQPGAFSEADKAILDQADAALETARKAMDDQALHLALGAIFAVVAEANRYFAGQEPWALRKTDPARMGTVLYVTAEVLRRVGIMVQPFIPQSAEKLLDILAAPADKRQFADVLASPLAGGTDLPAPQPVFPRYVEADEQN
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_PINTA
Sequence: MGRRPARCYRQIKNKPYPKSRYCRGVPDPKIRIFDVGAKKRLVDEFPFCVHLVSWEKENVSSEALEAGRIACNKYMVKFAGKDGFHLRVRVHPFHVLRSNKMLSCAGADRLQTGMRGAFGKPQGTCARVAIGQVLLSVRSRDNHSNHAQEALRRAKFKFPGREKIIVNRKWGFTKYTRADYLKWKTENRIVPDGVNPKLLGCRGPLSNRKPGQAFLKPAVVLSSDLVA
What are the official names of this protein?
60S ribosomal protein L10, Wilms tumor suppressor homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: GGGPS_METBU
Sequence: MQVEEYLNDIAEREGTVHLTLIDPASQSPEAAAEIAKAAVAGGTDAILIGGSTGAVGVALDQTLIKIKEQVDVPTILFPGNAGGVSTHADAIFFMSLLNSRDINYIITNQVMGAPVVYKSGIEPISMAYIISEPGGTVGWVGDAKLIPRNKPEIAAAYSLAGKYMGMHYTYLEAGSGADRPITPETIGAVKHVLGDNKLIVGGGIRDGKTAKICADAGADMIVTGTIVEETDDVRKKIEEIVSAIKK
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEA_PROMP
Sequence: MTDFDTKKLNKKWTIEDSISTYGIDKWGEKYFSINSEGNISISPDNKSQKKIDLFKLVKEFKSREINTPLIIRFNDILKDRIAELNNAFSQAIETYDYKNIYKGVFPIKCNQQRNVLEKIIEYGDRWNFGLEVGSKSELLIGLSILENQKSLLICNGYKDKKYIETAILARKLGKHPIIVIEQRDEVKRIIEAVKDLKATPILGIRSKLSSKSSGRWSKSVGDNSKFGLSIPEIMLTIKELKEANLINEMMLLHFHVGSQISDISVIKDALQEASQIFVELSKLGAPMKYIDVGGGLGIDFDGTKMSSNTSTNYSLQNYANDVIATVKDSCEVNNIQHPIIISESGRAIISHCSVLIFNILGTSHVSSQVKVSDQKKQSLIITNLIETLNQIKNLRDKKEDLSEIIELWNDAKKFKEDCLVAFRLGFICLEERAYAEELTWACAKEIANQLENNEIIHPDLSEITDTLASTYYANLSVFKSIPDTWAINQVFPIIPIHRHLEEPFCKGHFADLTCDSDGKLNNFIDNGKIKSLLNLHPPEKNNDYLIGIFMAGAYQEALGNFHNLFGNTNVIHIDINEDNSYKIKNIIKENSKSEILELLDYSSDNLVESIRVNTESAINNKTLTIQEARKLIDQIETSLRKSSYLSE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: RL18_ROSCS
Sequence: MAQRTPRELRLRRHRRVRKKVSGTPQRPRLCVFRSNMHIYAQVIDDTVGRTLAAASTVEPELRASLAGKTKTERAKVVGAAIAERARAVGIECVVFDRGGFKYHGRIQALADAAREGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TRX2_YEAST
Sequence: MVTQLKSASEYDSALASGDKLVVVDFFATWCGPCKMIAPMIEKFAEQYSDAAFYKLDVDEVSDVAQKAEVSSMPTLIFYKGGKEVTRVVGANPAAIKQAIASNV
What is the function of this protein?
Participates as a hydrogen donor in redox reactions through the reversible oxidation of its active center dithiol to a disulfide, accompanied by the transfer of 2 electrons and 2 protons.  It is involved in many cellular processes, including deoxyribonucleotide synthesis, repair of oxidatively damaged proteins, protein folding, sulfur metabolism, and redox homeostasis.  Thioredoxin-dependent enzymes include phosphoadenosine-phosphosulfate reductase MET16, alkyl-hydroperoxide reductase DOT5, thioredoxin peroxidases TSA1 and TSA2, alkyl hydroperoxide reductase AHP1, and peroxiredoxin HYR1.  Thioredoxin is also involved in protection against reducing stress.  As part of the LMA1 complex, it is involved in the facilitation of vesicle fusion such as homotypic vacuole and ER-derived COPII vesicle fusion with the Golgi.  This activity does not require the redox mechanism.  Through its capacity to inactivate the stress response transcription factor YAP1 and its regulator the hydroperoxide stress sensor HYR1, it is involved in feedback regulation of stress response gene expression upon oxidative stress.
What are the official names of this protein?
Thioredoxin-2, Thioredoxin II, TR-II, Thioredoxin-1.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Nucleus.
Protein: RS15_JANSC
Sequence: MSITPEEKARLMKEFATKEGDTGSPEVQVAILTSRISTLTEHFKSHKKDNHSRRGLLMMVAQRRKLLDYARAKDEGRYQDLIKRLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PRRX1_MOUSE
Sequence: MTSSYGHVLERQPALGGRLDSPGNLDTLQAKKNFSVSHLLDLEEAGDMVAAQADESVGEAGRSLLESPGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPIVPRPAPRPTDYLSWGTASPYSAMATYSATCANNSPAQGINMANSIANLRLKAKEYSLQRNQVPTVN
What is the function of this protein?
Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types.  The protein binds to an A/T-rich element in the muscle creatine enhancer.
What are the official names of this protein?
Paired mesoderm homeobox protein 1, Homeobox protein K-2, Homeobox protein mHox, Paired-related homeobox protein 1, PRX-1.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL18_FRATF
Sequence: MDKKTARLSRSKRTRIKLRELGHTRLCVYRTPRHVYAQVISGDGSTVLVAASTVEKDVKAKCKYTGNVESAAIVGEIIADRCKEKGISQVAFDRSGYKYHGRVKALVEAAREHGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PYRI_PROMH
Sequence: MTHDHKLKVEAIKRGTVIDHIPAQVGFKILSLFRLTETDERITVGFNLPSENLGKKDLIKIENVFLTAEQANRLAMYAPQATVNIIDDYQVVNKMALSLPELLEDVVPCPNSNCISHNEPVQSSFRVKKFASDVVLTCKYCEKEFERHAVIR
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: PHS_MYCTU
Sequence: MAVLTDEQVDAALHDLNGWQRAGGVLRRSIKFPTFMAGIDAVRRVAERAEEVNHHPDIDIRWRTVTFALVTHAVGGITENDIAMAHDIDAMFGA
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.