PharMolix/UniProtQA huggingface dataset:
Protein: SYP_ECOLU
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_STRPI
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_RALSO
Sequence: MSAPLANDTFLRALRRQPTEYTPLWLMRQAGRYLPEYNATRARAGSFLGLAKSPAYATEVTLQPLDRYPLDAAILFSDILTVPDAMGLGLSFEQGEGPRFARPVRSEADVAALSVPDMASLQYVFDAVSEIRRALVQDGRQRVPLIGFSGSPWTLACYMVEGGGSDDFRTVKSMLYARPDLMHRILEINAAAVIDYLNAQIDAGAQAVMVFDTWGGALADGIYQTFSLAYMARVVEGLRAGADGQRVPVILFTKGGGLWLESMAQTGADALGVDWTVNLQLARVRTGGRVALQGNLDPTVLFAEPDAIRAQVRRVLEDYAAGGDSDGHVFNLGHGISQFTPPESVAVLVDEVHTFSRALRTRLP
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_XANC5
Sequence: MSDNNEKQTLRTVEGRVVSNKMDKTVTVLVERQVKHALYGKYIKRSTKLHAHDADNACNEGDVVRVTEIAPMSKTKNWRVVEIVTRSAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: MENH_ECOK1
Sequence: MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLYVDLPGHGGSATISVDGFDDVTGLLCKTLVSYNILNFWLVGYSLGGRVAMMAACQEPAGLCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQRRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPAGVIASLAQILRF
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: GUAA_STRPB
Sequence: MTEISILNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITAQELREINPIGIVLSGGPNSVYADNAFGIDPEIFELGIPILGICYGMQLITHKLGGKVVPAGQAGNREYGQSTLHLRETSKLFSGTPQEQLVLMSHGDAVTEIPEGFHLVGDSNDCPYAAIENTEKNLYGIQFHPEVRHSVYGNDILQNFAISICGARGDWSMDNFIDMEIAKIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKDEGDQVMGMLGGKFGLNIIRVDASKRFLDLLADVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGIALGMPEEIVWRQPFPGPGLAIRVMGAITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWDVLKKISTRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: HXK1_HUMAN
Sequence: MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVHGSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGVEGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLGVEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLTKDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGFTFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDDIRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRGIFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAAVVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKGAALITAVGVRLRTEASS
What is the function of this protein?
Catalyzes the phosphorylation of various hexoses, such as D-glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6-phosphate, respectively) (PubMed:1637300, PubMed:25316723, PubMed:27374331).  Does not phosphorylate N-acetyl-D-glucosamine (PubMed:27374331).  Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity).  Involved in innate immunity and inflammation by acting as a pattern recognition receptor for bacterial peptidoglycan (PubMed:27374331).  When released in the cytosol, N-acetyl-D-glucosamine component of bacterial peptidoglycan inhibits the hexokinase activity of HK1 and causes its dissociation from mitochondrial outer membrane, thereby activating the NLRP3 inflammasome (PubMed:27374331).
What are the official names of this protein?
Hexokinase-1, Brain form hexokinase, Hexokinase type I, HK I, Hexokinase-A.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol. Note=The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (Probable). Dissociates from the mitochondrial outer membrane following inhibition by N-acetyl-D-glucosamine, leading to relocation to the cytosol (PubMed:27374331).
Protein: C554_HALH2
Sequence: AGDAAAGEDKIGTCVACHGTDGQGLAPIYPNLTGQSATYLESSIKAYRDGQRKGGNAALMTPMAQGLSDEDIADIAAYYSSQE
What are the official names of this protein?
Cytochrome c-554(548), Cytochrome c554.
Protein: RS14_CHLT3
Sequence: MAKKCVVVRNEKRKQIVEKYASKREELKKQGDYEALRKLPRDSSPTRLKNRCSITGRAKGVYKKFGLCRHILRKYALEGKIPGMKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: SYE_PSET1
Sequence: MTIRTRVAPSPTGDPHLGTAYIALFNYCFAKQQGGEFVLRIEDTDQVRSTAESEQAIMDSLRWLGLEWDHGPDVGGEFGPYRQSERSDLYKKYAHQLVDDGKAFYCFATSEELDKMREEQMAEGLRPKYDGRGLNHTDDEIKANLAAGKPYVIRMKIPSEGTFKFNDYLRDEIEIPWENVDMQVLLKADGFPTYFLANVVDDHHMQISHIFRGEEWINSAPKLLKLYEDFGWEAPVLGHLPLLRNPDKSKLSKRKNPTSINYYKEMGYLPEAVLNYLGRMGWSMPDEREKFTLNEMIENFDMKRVSLGGPVFDVDKLSWLNGMWIRENLTDEQLIQRFVDWKFNGEMLAKVLPEAKARINTLSDLVDLAGHFVGGIPTYDPALLTAGKADEDVIRQALQFFVWQLEGLRSFDKPAIFAIAKEVATFHELKIKDFLEPIFVAITGKTSSTSVLDAMEILGSDLSRARLRVALAHLGISKKQAKNIERAYREYPSA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_DEIRA
Sequence: MTVPDPARPAASPSARPRVLVANDDGIFAPGIKALGLALSEWADVVVVAPDVEQSAVGHGITIRRPLRFKHTAAAGFGDIPAYRVDGTPADCVVLGVHLLGRPDLVVSGINIGPNLGEDLTHSGTVAAAIEGLTLGLPSIAFSQFANEAGEYDFGPSAAYASRLAREVCCRGLPPRVLLNVNFPRVSPRGVRVTEVGLHRWEDSVVTRQDPEGRDYHWVAGVSTAHDGHDEQTDYGAVQAGFISVSPVRLDLTARDLIGELTQALPPL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_ACIBS
Sequence: MSFEQKPKVTVILANLGTPDEATVPAVRRFLKQFLSDPRVIEIPKFIWWIILNLFVLPFRPKRAAHAYASVWSTDSPMREIVFEQTQRVQAYLERENKQFDLTVLPAMTYGNLGIDAVLEKLSAHPQEHVILLPLFPQYSATSTAPLYDAFAKWIPTQRNLPGLTIIKDYYQHPMFIQALAESVLAYQEQHGKPEKLLMSFHGIPQPYADKGDPYADRCRITAKLVAEALHLKDDEWAISFQSRFGKQEWVKPYTDQLLQDWAKQGVKSVQVLSPAFSADCLETLEELAIQNAELFQQAGGGSYAYIPALNSDQAHIDLLAGLVQANLDALTHTLAHR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VL1_HPV24
Sequence: MSVWLPASGKVYLPPSTPVAKVQSTDEYIQRTNIFYHAYSDRLLTVGHPYFNVYNNDGTVLEVPKVSGNQHRVFRLKLPDPNRFALADMSVYNPEKERLVWGCRGVEIGRGQPLGVGTSGHPLFNKVNDTENPVSYRTQASSTDDRQNTSFDPKQIQMFIIGCAPCIGEHWEVAERCAGDNNDAGRCPPIKLVNSVIQDGDMADIGYGNLNFRTLQQSRSDVSLDIVNETCKYPDFLKMQNDVYGDSCFFFARREQCYARHFFVRGGKPGDDIPGEQIDAGTYKNDFYIPAATGQTQKNIGNSMYFPTVSGSLVSSDAQLFNRPFWLQRAQGHNNGICWANQLFITVVDNTRNTNFSISVYTENGKVTDINEYDANKFREYQRHVEEYEISLILQLCKIPLKADVLAQINAMNPSLLEEWQLGFVPAPDNPLQSTYRYIESLATPCPDKVAPKEREDPYAPYTFWNVDLSERLSLELDQYSLGRKFLFQAGLVQKTSKKTSNVSKGTKRKRT
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: MTLN_HUMAN
Sequence: MADVSERTLQLSVLVAFASGVLLGWQANRLRRRYLDWRKRRLQDKLAATQKKLDLA
What is the function of this protein?
Positively regulates mitochondrial complex assembly and/or stability (By similarity).  Increases mitochondrial membrane potential while decreasing mitochondrial reactive oxygen species (PubMed:29949756).  Increases mitochondrial respiration rate (PubMed:29949756).  Increased mitochondrial respiratory activity promotes myogenic differentiation which facilitates muscle growth and regeneration (By similarity).  Increases mitochondrial calcium retention capacity (PubMed:29949756).  Plays a role in maintenance of cellular lipid composition through its interaction with cytochrome b5 reductase CYB5R3 which is required for mitochondrial respiratory complex I activity (By similarity).  Interacts with the mitochondrial trifunctional enzyme complex (MTE) and enhances fatty acid beta-oxidation (PubMed:32243843).  Not required for MTE formation or stability (By similarity).  Modulates triglyceride clearance in adipocytes through its role in regulating fatty acid beta-oxidation and lipolysis (PubMed:32243843).
What are the official names of this protein?
Mitoregulin, Micropeptide in mitochondria, Micropeptide regulator of beta-oxidation, Small integral membrane protein 37, lncRNA-encoded micropeptide.
What is the protein family that this protein belongs to?
Belongs to the mitoregulin family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Note=Preferentially binds to cardiolipin relative to other common cell membrane lipids.
Protein: UVRA_RICTY
Sequence: MNEEYIKVRGAKEHNLKNINVDIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSSYARQFLHLQNKPNVESISGLSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIPYSPVTGLPIHSQTVAEMVDIINELPKGTKVYLLAPIVRGHKGEFRREIINLKKQGFQKLIVNGEVCEIDDLPKLDKNKKHNIEVIVDRIVLDENLGNRLADSLESSLNLADGITYLEIVELPQAVKSQFKKNQRITFSEKYSCPVSGFHLTEIEPRIFSFNSPFGACPKCEGIGKEFFFDRDLIVQDQRISIKDGAIVPWGSTSSKFILETLKALADHYKFSIEVPFISLSQNVKDILFEGSGEEEIKFEFHDGSKTQIIKQPFAGIIPSLQEKDRTIESVLIKEELAKFKSEHKCTACSGFRLKDEALCVKIANLHIGEVAGMSIAALQKWFSHLEEKLNQKQLFIAKRILKEINERLKFLMNVGLDYLTLSREAGTLSGGESQRIRLASQIGSGLSGVLYVLDEPSIGLHQRDNTRLIATLKRLRDLGNTVLVVEHDEETMYEADHIIDIGPGAGIHGGRVIAEGNAEKIKHFEESITGRYLSGRQTIKVPSETRVGHDNRAIELLGAVSNNLDNVDIKIPLGTFTAITGVSGSGKSSLMIHTLYKAALKHLEPTSKVFPGKYRELKGLEYIDKIIDINQSPIGRTPRSNPATYTGAFTHIRDWFVELPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNGHRYNRETLEIKYKGKSIADILMMTVEDAMQFFDKIPLIYEKLITLNEVGLGYIKIGQSATTLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDIKKLLKVLHKLVDMGNTVLVIEHNLDVIKTADYIIDVGPEGGDKGGKIVVCGTPADIAACKESHTGRYLKQYLV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_SYNPW
Sequence: MAREKFERNKPHVNIGTIGHVDHGKTTLTAAITNVLAKKGQAKVQDYADIDGAPEERERGITINTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMAQTKEHILLAKQVGVPALVVALNKCDMVDDEEIIELVEMEIRELLSSYDFPGDDIPVVQVSGLKAIEGEAEWEAKIDELMQAVDANIPEPEREVDKPFLMAIEDVFSITGRGTVATGRIERGIVKVGEEIEIVGIKDTRKTTVTGVEMFRKLLDEGMAGDNVGLLLRGIQKEDIERGMVLVKPGSITPHTKFEGEVYVLKKEEGGRHTPFFAGYRPQFYIRTTDVTGQITAFTADDGSDVEMVMPGDRIKMTGELICPVAIEQGMRFAIREGGRTIGAGVVSKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STUA_GIBZE
Sequence: MNQSHHQQSEMYYPQYPTQQYNPYPYPTNGAHAPAVSTPMPGPQNVLPVPSALSNQGAMPQAAYSNNAPAGNFDTTGQHNPPGMKPRVTATLWEDEGSLCFQVEARGICVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPYDRALDFANKEKITELLYPLFVHNIGALLYHPSNSNRTSQVMAAAERKKNEAIVGNRSLPSLVQSHHQMMPAMPTGYTSQQPLTNGHQSMANTPQPLTNGSQPPMNGSQTPMNGPQPPMQNGGSMLKRVREDDDDLHRSGPNGHDPMNNIHGMPNGYPHQSPLGSVHQPPMQNGNDGGLKRGREEHDDMHRAGPNGHDPMNNMPGGMPSLPNYAPPPLQNLHQPLSNGDSGMLKRGRDDDDDVHRSSPNGHDANGNFELKRRKTETSTSNDMLPQSPYYTLSNGAYQGPMMNSMNHYKRRDDEAETPRPGPNMNDLNNFDLKQRHKTMESSVPAPQYDAMNRPHSSIGNSPAYASAPTGYDHLTRPASTVAVSPSYPAGPGYELARPVTNVPRRQQSFG
What is the function of this protein?
Transcription factor that regulates asexual reproduction (PubMed:20879840).  Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (PubMed:20879840).  Controls the expression of the gene clusters involved in the production of deoxynivalenol (DON) and 15-acetyldeoxynivalenol (15ADON) (PubMed:20879840).  Regulates the expression of genes involved in chitin and glucan metabolism (PubMed:20879840).  Controls also catalase activity and cell surface hydrophobicity (PubMed:20879840).  Plays an important role in pathogenicity (PubMed:20879840).
What are the official names of this protein?
Cell pattern formation-associated protein StuA, Stunted protein A.
What is the protein family that this protein belongs to?
Belongs to the EFG1/PHD1/stuA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COAW_STAAN
Sequence: MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLGK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type II pantothenate kinase, PanK-II, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUREJ_STRPU
Sequence: MSVFVILILFNAILNFKTVGPAAVSSKTVDCASAPCMNGGTCADGFNNFTCFCEEGFTGSMCETEYGCFRPWFYGPAFGYCYLWERVDYNWTQARESCIDQGRGAELASIHSAEENAFVYAQIRRYAWIGLSDQVTEGVFDYADGTPVDYLSFPDKNKQSETRDCVYVKHLRVDNWSLLDCRANKTSICKSTTTFSATDGCATGWVHNPATGYCYFYEERGGMWSKGREFCLDAGADLASIHSAEENAFIFDMLTEFVWLGLNDLETEGVYTNFSDGTPADFDNFPADNYQNEDHDCVSIRHLEKTDRYWFFLGCDDTVTSICKRPHEVVATQAPPYLFTTTDVPATTTTIPTTTTTISATTRTIDAMILIELLLFPNNVSSIDNIFRVNNTILVTASVLGSFQALSSQILWSITNHLSGDSVQYTVYSEDAVLVRFTTVSIFTIKATAVGNSHNLTATANATVKHVCISSLTTSVKEHCDAPHPAVYLRAFDIHISTHMELNGKCIDPMTPDFKWRIFTSTEADDVVTAFEKITHTRQVMIPRGTLPYGIYSLNLNAKTRLKTSGEVTGEKEIISWLEIQPPPLVAVIKGGASRSHGVSSNLIVDGSNSYDPDVPPGSSSNVTFLWYCVVVDPDVMYSSLDEAIQNTDNACFEDEGIMMNSTSSMIEVIANKLNANVTMNFWLNISKEGQISGLTQQRIHLTLGLLPEIEISCISNCNMYIFTAERLVLHASCTNCDSENEDVSFRWSLESNHTSVIGDLSSQTTTGLDQPYLVLKPLTFDSISEMGSIILRVTGSQSDSDGYAEFSVDLPHNAPPALGSCVVTPDEGYALQTDFTVTCSNFTDVDEPLTYQIILFSHVDVVDWMFVGRGEGFQLYEGSAPIKDGLYLPVGVGTDDHDILLQVNVRDCNMASTSVYISATVHPPTLDAVGMNLVQELLDMALLVETNVNALLAVGDPGQAAQLISALGSILNSIGDEDDSEEGRETRSEIRSFLVDCVAAIPVESMTSLKQSSAALAVVTHNKQEISTHVQMLAASTLSEMTSFVKSKSGSYTQAQENIESAGTILVEGLSNILSAAKETERLLSDDTSQEREDHKNLIEVAVSTINDIQDAIVAGKIPSEAATIITSPALSIAVGSISRDELAEATFGGPEDLGSFRMPSQDVLNQAMEHALGTTVSMKMSAMKWNPFSWPGAGGESIKSSIVGIQLEADQMLEFHDLTADIDVYLPMRETLSADPVSVHITKTSSDSVLIDHSSLPVDGALHLTVIAENEPMVALSICTARISITESSCVGTDTPLGVSNEDPDTDANFTWTVPLVDLKAADGIMIRLYDSEDQPGYENDNITLSVFMHTLQCNFWNEDQQEWDSTGCKVGPLSKPSTTHCLCNHLTGFFGSSILVPPNHAQPVIGGHKLTGVDFLICVLIGYGIYCVALVIRVVGCSFAIRVHKVL
What is the function of this protein?
Receptor for the egg jelly ligands inducing the acrosome reaction.  Could be a regulator of sperm ion channels.
What are the official names of this protein?
Sperm receptor for egg jelly, suREJ.
What is the protein family that this protein belongs to?
Belongs to the polycystin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Present on the surface of the sperm flagellum and also on a thin belt of membrane directly over the acrosomal granule at the anterior apex of the sperm head.
Protein: TFIIB_ASFM2
Sequence: MDALLKEIEKLSQPSLQKENNDVCDLCFMQMKKISNYQLLCEECGQLKDWFEPEYNEKFTVYSRLKIVGANSSYHQRDLDKANSSDYSSLQFHHILEELKSLNVKYMDAGQKPFPIQVLKETAHSYNQVQQHRVIRSITKLQILASILRSICLKLNIACTVADAARFTQLNTKGISKGMDLLRSLFVDNKITLNVDLNPIDSFINSTYSALQIKQIHQELQEENVYNLKEIVKSFILYADEKNIGVDLNRRTVVIATMYNVLRRAYYPIEIDTVVYQCKIRKNTITRALKMYEDYYSHFKSLYEQYHLNAAKKLI
What is the function of this protein?
Putative initation factor.
What are the official names of this protein?
Initiation factor TFIIB homolog, pC315R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C315R family.
Protein: MYL9_HUMAN
Sequence: MSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILKHGAKDKDD
What is the function of this protein?
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation.  Implicated in cytokinesis, receptor capping, and cell locomotion (PubMed:11942626, PubMed:2526655).  In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity).
What are the official names of this protein?
Myosin regulatory light polypeptide 9, 20 kDa myosin light chain, LC20, MLC-2C, Myosin RLC, Myosin regulatory light chain 2, smooth muscle isoform, Myosin regulatory light chain 9, Myosin regulatory light chain MRLC1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts.
Protein: CH60_BACLD
Sequence: MAKDIKFSEEARRSMLRGVDALADAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDAFENMGAKLVAEVASKTNDVAGDGTTTATVLAQAMIREGLKNVTAGANPVGVRKGIEQAVAVAVESLKEISKPIEGKESIAQVASISAADEEVGSLIAEAMERVGNDGVITIEESKGFTTELEVVEGMQFDRGYASPYMVTDSDKMEAVLENPYILVTDKKITNIQEILPVLEQVVQQGKPLLLIAEDVEGEALATLVVNKLRGTFNAVAVKAPGFGDRRKAMLEDISILTGAEVITEDLGLDLKSTQINQLGRASKVVVTKENTTIVEGAGDTEQIAARVNQIRAQVEETTSEFDKEKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVSGGGTALVNVYNKVAALEAEGDELTGINIVLRALEEPIRQIAHNAGLEGSVIVERLKNEEIGVGYNAATGEWVNMIDKGIVDPTKVTRSALQNAASVAAMFLTTEAVVADKPEENKGGAGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.