PharMolix/UniProtQA huggingface dataset:
Protein: RS272_ARATH
Sequence: MVLQNDIDLLNPPAELEKRKHKLKRLVQSPNSFFMDVKCQGCFNITTVFSHSQTVVVCGNCQTILCQPTGGKAKLTEGCSFRRKGD
What is the function of this protein?
May be involved in the elimination of damaged mRNA after UV irradiation.
What are the official names of this protein?
40S ribosomal protein S27-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: AMPL_YEAST
Sequence: MEEQREILEQLKKTLQMLTVEPSKNNQIANEEKEKKENENSWCILEHNYEDIAQEFIDFIYKNPTTYHVVSFFAELLDKHNFKYLSEKSNWQDSIGEDGGKFYTIRNGTNLSAFILGKNWRAEKGVGVIGSHVDALTVKLKPVSFKDTAEGYGRIAVAPYGGTLNELWLDRDLGIGGRLLYKKKGTNEIKSALVDSTPLPVCRIPSLAPHFGKPAEGPFDKEDQTIPVIGFPTPDEEGNEPPTDDEKKSPLFGKHCIHLLRYVAKLAGVEVSELIQMDLDLFDVQKGTIGGIGKHFLFAPRLDDRLCSFAAMIALICYAKDVNTEESDLFSTVTLYDNEEIGSLTRQGAKGGLLESVVERSSSAFTKKPVDLHTVWANSIILSADVNHLYNPNFPEVYLKNHFPVPNVGITLSLDPNGHMATDVVGTALVEELARRNGDKVQYFQIKNNSRSGGTIGPSLASQTGARTIDLGIAQLSMHSIRAATGSKDVGLGVKFFNGFFKHWRSVYDEFGEL
What is the function of this protein?
Resident vacuolar enzyme that catalyzes the removal of amino acids from the N-terminus of peptides and proteins.  Also acts as the major cargo protein of the cytoplasm-to-vacuole targeting (Cvt) pathway.  The precursor form of aminopeptidase 1 (prApe1) assembles into dodecamers and the propeptide mediates the aggregation of dodecamers into higher multimers.  The multimers are then recognized via the propeptide by their receptor ATG19, and ATG19 further interacts with ATG11, which tethers the APE1-ATG19 complex to the pre-autophagosomal structure (PAS).  The cargo-receptor complex (also Cvt complex) is selectively enwrapped by a double-membrane structure termed the Cvt vesicle under vegetative growth conditions and by a similar but larger double-membrane structure termed the autophagosome under nitrogen starvation conditions.  The Cvt vesicle or the autophagosome fuses with the vacuolar membrane and release its content in the vacuolar lumen.  In the vacuole, prApe1 is processed into mature aminopeptidase 1 (mApe1).
What are the official names of this protein?
Vacuolar aminopeptidase 1, Aminopeptidase yscI, Leucine aminopeptidase IV, LAPIV, Lysosomal aminopeptidase III, Polypeptidase, Vacuolar aminopeptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
What are the subcellular locations of this protein?
Vacuole. Note=Transported to the vacuole by the cytosol-to-vacuole targeting (Cvt) pathway.
Protein: TSC10_EMENI
Sequence: MHPSLPSIIYDASPTALGISAVFGALFFYTLVKMFGFLARENQFVVEGRTVVITGGSEGMGKAVACQLAQKGANIVIVARTLQKLEEAIEAIKGSAANVNKQRFHYISADLTKPEECERIMTEVTEWNDGMPPDIVWCCAGYCTPGYFVETSVQTLKDQMDTVYWTAANTAHAILRKWLVPINPSHQRPLPRRHLIFTCSTLAFVPIAGYAPYSPAKAAMRALSDTLCQEIEVYNGSRASKERARATPADVKIHTVFPMGILSPGFDNEQQIKPALTKQLESADKPQTPKEVARIAIEAIERGEYLITTMFVGDVMKGAALGPSPRNSWFRDTCTGWLSNLLFLGVVPDLRKQAFNWGAKNGVPTSPSA
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
3-ketodihydrosphingosine reductase tsc10, 3-dehydrosphinganine reductase, KDS reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: TTM1_CAEEL
Sequence: MTISMISPSSIRLSSDKRDSSSSNLPANIEEDTQSVSSSDSGVSADSIDHHHHGHGHGHSHGGHGHSHTHNNDDSSSDCSGAGGGAHKHSHDEKYQKGRRAEKVLWAVAALSAVFIAAEFVGGFWAQSLAIMTDAGHMLSDLLSFIISIFAIRCARLPASKRLSFGYERAEVLGALTSVIILWVLTTVLVVVAIQRIVNNEHEVDADVMLITAGVGVLFNIVMGLVLHFGTGGHGHTHGGHSSHGHAHDGKNVNVRAALIHVIGDLVQSIGVLIAALIIRFTGWTLADPICTFLFSIIVLFTTVTVMRDIFFVLMEATPSHYDLSDVKKALSALEGVKGVHDLHLWSIGMDKTAFSVHLALESPNRAMENVAEARSLIRRRFGVAVATVQVEPFDEKIDSCDTCQQQETA
What is the function of this protein?
Promotes excretion of zinc from intestinal cells into the intestinal lumen in response to increased dietary zinc (PubMed:23717214).  Involved in cadmium resistance, possibly by promoting its transport from cells (PubMed:15256590).  Involved in resistance to B. thuringiensis pore-forming toxin Cry5B downstream of the sek-1 and pmk-1 MAPK kinase pathway (PubMed:15256590).
What are the official names of this protein?
Zinc transporter ttm-1, Toxin-regulated target of MAPK 1, Toxin-regulated target of p38MAPK.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
What are the subcellular locations of this protein?
[Isoform a]: Cytoplasmic vesicle membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform b]: Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: ACCD_PHOLL
Sequence: MSWIEKILNKSNITQTRKANIPEGVWTKCDSCSQVLYRAELERNLEVCPKCDHHMRISARTRLATFLDEGATTELGGELEPKDILKFRDSKKYKDRISAAQKQTQEKDALVVMKGTLSGMSVVAAAFEFAFMGGSMASVVGARFVRAVEQALADNCPLICFSSSGGARMQEALMSLMQMAKTSAALAKMQERGLPYISIMTDPTMGGVSASLAMLGDINIAEPKALIGFAGPRVIEQTVREKLPSGFQRSEFLLAKGAIDMIVRRPEMRDTLASLLSKLTHQSQPGTKPIVAEFVAEPADVEADIQISTNKEDA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_CAMJJ
Sequence: MEYKRFKTRQIKVGNVLIGGDAPISVQSMLFTKTRDIEGSLEQINRLYFAGANIVRLACLDMADARALKEIKAKSPLPLIVDIHFNHNLAVYCAEFIDGVRINPGNIGSKENIKEVVKACKERGIPIRIGVNHGSIEKQFSDKFGYGVDAMLESAMYNIKLLEDLDFFDIKISMKTSDAQKTIEAYERLRPLCDYPFHLGVTEAGTKFHSTVKSSIALGNLLLKGIGDTMRVSMTGELEEEIRVARAILQDSGVQKSGVNIISCPTCGRIQSDLLSAIKIVEEKTKHIKEPLNISVMGCVVNALGEAKGADVAIAFGKNQGLVIRHGEVVAKLKESELVDRFLAEVEDEVKSRAVKE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RSMJ_CHRSD
Sequence: MSDAVVAVGEPLRDLAARLGLAWQAEGDATAALRLAMTPEGLALSGEARHYGAPIRVDFTAGKAAHRRRFGGGRGQLVAKACGLARGVTPSIVDATAGLGRDAFVLATLGAEVLLIERVAAIYALLEDGLGRASANAETAEIAARMRVAQGDAARELASLVARHDIAPQVVHLDPMFPHRDKSALVKKEMRVFRDLAGDDDDAPRLLEAALDVASHRVVVKRPRRAPPIEGPAPHHMLEGKTSRYDLYVHRSLKPE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIBB_RABIT
Sequence: ADDYDDEVLPDARGHRPIDRKREELPSLRPAPPPISGGGYR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: COX2_LACTC
Sequence: MLNLLYNQIFNVILNDVPTPYNTYFQDSATPNQEGILELHDNIMFYLLVILGLVSWLLFTITRTYSKNPIAYKYIKHGQTIEIIWTIFPAVILLIIAFPSFILLYLCDEVISPAMTIKAIGLQWYWKYEYSDFINDSGETVEFESYVIPEDLLEDGQLRLLDTDTSVVVPVDTHIRFVVTAADVIHDFAIPSLGIKVDAAPGRLNQVSALIQREGVFYGQCSELCGTAHSAMPIKIEAVSLPAFLEWLNEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LLDD_ACIB5
Sequence: MIISSGNDYRAAAQRRLPPFLFHYIDGGAYAEYTLKRNVQDLSEIALRQRVLNDMSALSLETKLFNETLSMPVALAPVGLTGMYARRGEVQAAMAADKKGIPFTLSTVSVCPIEEVAPAINRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPVPGARYRDAHSGMSGPNAAMRRYMQSVFHPHWSWNVGLMGRPHDLGNISKYLGKPTGLEDYIGWLGSNFDPSISWKDLEWIREFWDGPMVIKGILDPEDAKDAVRFGADGIVVSNHGGRQLDGVMSSARALPAIADAVKGDLAILADSGIRNGLDVVRMLALGADTVLLGRAFVYALAAAGGQGVSNLLDLIDKEMRVAMTLTGAKSISDINADCLVQAIKQGL
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRPA_CALS4
Sequence: MNRIDRRFDDLKKEGKKALITFITAGDPDIDTTYDIVLALEEAGADIIELGIPYSDPLADGPTIQASSQRALAKGIKIKDIMDLVMRIREKSDIPIVYLVYYNSVFKYGIEKFLEDSKNAGVDGLIIPDLPLEERKEVLDVADKYEIYLIPLVAPTSKERIKGITENGKGFVYCVTLTGVTGAREEITTDLEEYMRLVSSYTSMPKALGFGISGPEMARKLKSLSDGIVVGSAIVERIAKGYNRCEMLKEVKEFVLSLREVL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: LEUC_ALIFM
Sequence: MSNAKTLYEKIYDAHVAVAAEGENPILYIDRHLVHEVTSPQAFDGLREKGRKIRQVGKTFATMDHNVSTQTKDINASGEMARIQMETLSKNCEEFGVTLYDLNHKYQGIVHVMGPELGITLPGMTIVCGDSHTATHGAFGSLAFGIGTSEVEHVLATQTLKQARAKTMKIDVKGKVAEGITAKDIVLAIIGKTTAAGGTGYVVEFCGEAITDLTMEGRMTVCNMAIELGAKAGLIAPDQTTFDYIAGRKFSPQGADLDAAIEYWSSLKTDDDAEFDAVVTLDASEIKPQVTWGTNPGQVIAVDAPIPAPESFADPVEKASAEKALAYMGLEAGKSLSDYNVDKVFVGSCTNSRIEDMRAAAAIAKGRKVASHVQALIVPGSEQVKAQAEKEGLDVIFKEAGFEWRLPGCSMCLAMNNDRLGPHERCASTSNRNFEGRQGRDGRTHLVSPAMAAAAAIAGHFVDIRTITEQA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CN023_HUMAN
Sequence: MELSSMKICAAIPTSRALPEVVRRMPRKRISGLEWLLQQDPGFSLVNTVKAGMIISFPSNNIYSSVCCCQSEIFKYEFSNSKKSSWIQEERHLGKNNVLYSAHDVSPEKVTSALKKTNKQTTTINNFPLQYLPGSKLLDRFLSLSRSLLCLNSWSSSLPLAPQVKKK
What are the official names of this protein?
Uncharacterized protein encoded by LINC01551.
Protein: RIMP_LACLA
Sequence: MNDVVKIVEDFIRPHIPQPFELFAVEWEKFGGDMMLSILVDKEGGIEIDETAELSEIISPLLDTISPDPFPTEGYLLEVASPGAERPLRKAEHFAGAVGEYIFVKLYQKINNEKEITGDLVSFDGETLVVDVLDKTRHKNIEIPLSAVAKAQTMVKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y053_CLOP1
Sequence: MARGGFPGGMGNMNNLMKQAQMLQKQMQSMQEEIEASEFEGSAGGGAVVAKVNGKKELIALNIKPEVVDPDDVEMLEDLVFSAVKQALEKASEETSEKMGKLTGGMGMPGLF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein CPF_0053.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: MED28_ARATH
Sequence: MDYQQKPPQSSDPSPSPPDRPPGIRSPETPSNNQNNDIEDIMACVTALEAALLPCLPARELQAIDRSPHPSHQIDVERHARDFMEAAKKLQLYFMGLKREDRAPSRAESLKKDIAVMEEELKTKDELIKKHMRLFQESQKLVKEQIEKHRDELEKV
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 28.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 28 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YD387_YEAST
Sequence: MSTDESEDVYSDLYSIISQVTSNTANDIEQLPYALTFKTSLIFVGATIGGLLFGYDTGVISGVLLSLKPEDLSLVVLTDVQKELITSSTSVGSFFGSILAFPLADRYGRRITLAICCSIFILAAIGMAIARTLTFLICGRLLVGIAVGVSAQCVPLFLSEISPSRIRGFMLTLNIIAITGGQLVSYVIASLMKEIDNSWRYLFALSAIPAILFLSILDFIPESPRWSISKGDILYTRDSLRMLYPTASTYHVNSKIKQLIIELDKLRLYEDASEPLLVQSQSVIRYMDSSTSGTLSPPNIKRLSSNTERTSNTMSSSSAYLSALRGPAPNGALASNKKKRHRMEPRTIRALIVGCMLMFFQQITGFNAFMYYAAIIFSKFNIKNPLLPPILIASTNFIFTFFAMYTMDSLGRRAILLRTILIMTVGLLLCSVGFGHDQVNLLLISVVIYVAAYASAMGSVPWTCVEFLPLNRRSFGASCIACTNWLTNAFVSMTYLSTINTIGDENTMLIFAFFTVCAWFFVYFWYPEVKGLSLEEVGRVFDNGIDVHYVFRTYH
What are the official names of this protein?
Probable metabolite transport protein YDR387C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPE_ECO45
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLSTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RRG9_SCHPO
Sequence: MNIFNYTTLIFRRLSSTFKASNKASIEWKKQNIAVKRKIGGYWNPKKKLPLESMDEIRRLKKEKSSMSCSELAKLYGVSPESIRRILKSSNRPLDDREKSRKEKRWLNSLKSNRDFA
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Nucleus.
Protein: STK40_BOVIN
Sequence: MKRRASDRGAGETSARAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILTLEERGDQGIESQEERQGKMLLHTEYSLLSLLHTQDGVVHHHGLFQDRTCEVVEDAESNRMVKKMKKRICLVLDCLCAHDFSDKTADLINLQHYVIKEKRLSERETVVIFYDVVRVVEALHQKNVVHRDLKLGNMVLSKRTHRITITNFCLGKHLVSEGDLLKDQRGSPAYISPDVLSGRPYRGKPSDMWALGVVLFTMLYGQFPFYDSIPQELFRKIKAAEYTIPEDGRVSENTVCLIRKLLVLDPQQRLAAADVLEALSSIIASWQSLSSLSGPLQVVPDIDDQMSNADSSQEAKVTEECSQYEFENYMRQQLLLAEEKSSVHEARSWVPKRQSGAGVPPVRRLGHDAQPVNPLDAAILAQRYLRK
What is the function of this protein?
May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
What are the official names of this protein?
Serine/threonine-protein kinase 40.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: IOD3_PIG
Sequence: MPGQAGRRRLVGGGCRGSQGPLGGAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTACMLWLLDFLCIRKHLLGRRRRGEPETEVELNSDGDEVPPDDPPICVSDDNRLCTLASLRAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGFQNQHILDYARGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYSIPQHRSLEDRVSAARVLQQGAPECSLVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDQQLHGPQPRRV
What is the function of this protein?
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine).  RT3 and T2 are inactive metabolites.  May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones.  Can regulate circulating fetal thyroid hormone concentrations throughout gestation.  Essential role for regulation of thyroid hormone inactivation during embryological development.
What are the official names of this protein?
Thyroxine 5-deiodinase, 5DIII, DIOIII, Type 3 DI, Type III iodothyronine deiodinase.
What is the protein family that this protein belongs to?
Belongs to the iodothyronine deiodinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein.
Protein: PRMA_BURP6
Sequence: MSYRELVAELPREHAEALSDALVELGALSVSVEDADADTPDEQPLFGEPGLVPERTAWQHSRVIALVDATQDPAVLLAAAANEAGLAQAPRFELREVEEQDWVRLTQSQFEPIHIGEKIWVVPSWHDAPQPDALVLELDPGLAFGTGSHPTTRLCMEWLEQTVQPGQTVLDYGCGSGILAILAKKCGAGRVTGIDIDPQAVEAARHNSERNRADVTYGLPDDCPDGEFDIVVANILSNPLKLMASMLASKVKPGGRIALSGVLARQADEVASVYARYIDIAVWREHEGWVCLAGTRRESH
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CETZ_THEKO
Sequence: MRALIIGVGQCGTKIADLFALVDFDTIALNTSRGDLEYLKHIPHDRRILIGESITGGKGVNANPLLGREAMKRDLPLVMRKIGSIVGYEDVDIFFLTFGFGGGTGAGGTPVLAEALKEEYPDSLVVAIGALPLKEEGIRPTINAAITIDKLSKVADSIIAIDNNKLKESGDDISSAYEKINYTIVERIASLLALVDVPGEQTLDASDLKFVLKAFGSFATVGYAKADASKVKNLSRLIIKSFESEGLYLDANIESALYGLVAIHGPPEVLKASDIFEALDYLTSKIRGKQIFRGFYPDPRERDVEVVTLLSGIYESKSIENIVRTAKEYARSFMQAKSEAETKKKELLTGLPDFDDVYPSLEATGSDDPEGFAEYREVSR
What is the function of this protein?
Involved in cell shape control.
What are the official names of this protein?
Tubulin-like protein CetZ.
What is the protein family that this protein belongs to?
Belongs to the CetZ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGN1_CAEEL
Sequence: MYHHSPFYPHHLQTGEQDLDMERENDMDQNSKNSTQKPVKREKRRYRCRKRSPATIERAKTVRRDKANARERRRMNSLNDALEHLRGILPALPDEPKMTKIETLRKAQEYIASLSFQLSGGSPDSSQCCETGSCGLCSASQSLQSTPFQSPCFPQPLQYPSSYSNPPSQMYYHHHHQSPSFPHH
What is the function of this protein?
Acts as a transcriptional regulator (By similarity).  Regulates expression of various genes, including homeobox protein unc-42 and helix-loop-helix protein hlh-34 (PubMed:32273286).  Required for embryonic viability, neuromuscular development, organization of the nerve ring and neuronal cell body location (PubMed:32273286).  Regulates AIY neuron axon morphology and cell fate (PubMed:32273286).  Plays a role in cell autonomously establishing a neuronal left-right asymmetry (PubMed:21041366).  Involved in regulating glial specification (PubMed:32665354).
What are the official names of this protein?
Helix-loop-helix protein ngn-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECA_YERPY
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKNANTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKDGDVVVGSETRVKVVKNKIAAPFKQAEFQILYGEGININGELVDLGVKHKLIEKAGAWYSYNGDKIGQGKANASNYLKENPAIAAELDKKLREMLLNGGNGEQPVAAATAEFADGADETNEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBID_SALA4
Sequence: MGELSFDAPVWHHGKALRKGYTTGSCATAAAKVAALMVLRQHLIHQVSIVTPSGVTLCLNVESPHIEGQQAIAAIRKDGGDDVDATHGMLIFARVTLNDSGEITLTGGEGIGTVTRKGIGLPLGSAAINRTPRHTIESAVREAIGPARGADVEIFAPEGEARAQKTYNSRLGILGGISIIGTTGIVTPMSEESWKRSLSLELEIKRASGLTRVILVPGNHGERFVREQMGVDTQAVVTMSNFVGYMIEEAVRLGFCQIVLVGHPGKLIKIAAGIFHTHSHIADARMETLVAHLALLGAPLELLTLVSDCDTTEAAMEHIEAYGFGHIYNHLARRICLRVMQMLRFTKTPPVCDAILFSFDNHILGSNRPVDEIAKELQC
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.