PharMolix/UniProtQA huggingface dataset:
Protein: COAD_LEPIC
Sequence: MKHLAIYPGSFDPLTKGHLDILQRSLGLFDKVIIAIAVNSNKSTLFSIEERLGFIREVTKGMKGLEIDTFQGLTVDYCNKVGANSIIRGLRAVTDFDYEYAISLMNKKLAPNVETVFLMSSGEYSFISSTIVKEVARHGRDVSNQVPEIVSKALLKKLSQ
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GROA_SHEEP
Sequence: MARAANPAPRLLGAAMLLLLLVAAGRRAAGAPVVNELRCQCLQTVQGIHLKNMQSVKVTPPGPHCGQTEVIATLKTGQEVCLNPAAPMVKKIIDKMLNQASSN
What is the function of this protein?
Has chemotactic activity for neutrophils.
What are the official names of this protein?
Growth-regulated alpha protein, C-X-C motif chemokine 1.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YTXE_BACSU
Sequence: MKLRRERFERRNGSGKNSQSSSSWMVTFTDLITLILVFFILLFSMSQIDLQKFKAAVDSIQKEGNGLQPDQTSIEKKNTSPSDTKKQEDQQDQLLKKVNTYIKDNHLKAQMTAKRDERGVVLVLQEAVLFDTGEAKVLKNAETLLHQIAVLLQTIPNDIQVEGHTDSRNISTYRYPSNWELSAARASGVIQYFTSKEKLPSKRFIAVGYADTKPVKDNKTNEHMKENRRVEIVIKKSKTTSS
What is the function of this protein?
May be involved in some transport function.
What are the official names of this protein?
Uncharacterized protein YtxE.
What is the protein family that this protein belongs to?
Belongs to the MotB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: UVRC_ESCF3
Sequence: MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVAGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLIARMEKASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLTELAGRRINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLSALATVLKLPEVKRMECFDISHTMGEQTVASCVVFDANGPLRSEYRRYNITGITPGDDYAAMNQVLRRRYGKAIEESKIPDVILIDGGKGQLAQAKAVFAELDVPWDKNRPLLLGVAKGADRKAGLETLFFEPEGEGFSLPSDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSTLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C19_RAT
Sequence: MTSYSYRQSSAMSSYGGMGGGPVRFGSGGVFRAPSIHGGSGGRGVSVSSTRIVSSSSGGYVGGRGGSFSGALTVTDGLLGGNEKITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKQGPGPFRDYSQYFKTIEDLRDKILGATIENSKIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIENLKEELAYLKKNHEEEISALRSQVGGQVSVEVDSTPGIDLAKILSEMRSQYEAMAEKNRKDAEAWYLTQIDELNTQVAVHTTQIQINKTEVTELRRKVQDLEIELQSQLSMKAALEGTVAEIEARYGAQLSHIQGVISSIEVQLSNVRADTERQNQEYQQLMDIKSRLEQEIATYRSLLEGQEAHYNSLSIAKAL
What is the function of this protein?
Involved in the organization of myofibers.  Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity).
What are the official names of this protein?
Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, Type I keratin Ka19.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: K6PF_THEKO
Sequence: MVRELLEKARGLSMFTAYNTNVDAIVYLNGETVQRLIDEFGAEAVKRRMEEYPREINEPLDFVARLVHALKTGKPMAVPLVNEELQAWFDSHFKYDVERMGGQAGIIANLLANLDFREVLVYTPHLAKRQAEMFVKKPNLFYPVVEGGKLVLKHPWEAYRENDPVKVNRIFEFRAGTTFRLGNETITVPFSGRFIVSARFESIRIYTEPELKPFLPEIGQRVDGAILSGYQGIKLRYSDGKDANYYLREAKKDILLLKREKDVKVHLEFASIQNRELRKKVIYNLFPLVDSVGMDEAEIAYVLSALGYDKLAERIFTYNRIEDTVLGGKILIDEMNLELLQIHTIYYIMYIAHANNPLSEAELRQSLELATTLAASRASLGDIASPDQISVGMNVPYNERGEYVKLRFEEAKRRLRTKEYKLVIIPTRLVQNPVSTVGLGDTISTGAFTSYLAMLKEKGEL
What is the function of this protein?
Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor.
What are the official names of this protein?
ADP-specific phosphofructokinase, ADP-dependent phosphofructokinase, ADP-Pfk.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHMD_TOLAT
Sequence: MVLPKIKEVRAWFTGGATAEKGAGGADYHDQGNHHWIDDHIATPMSKYKQYEQSRQSFGINVLGTLVIEVEADNGQIGFAVSTAGEMGCFIVEKHLNRFIEGKCVSDIKLIHDQMLGATMYYAGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAVRDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDKGIRKDAAMVAEYREKCGPDFWLMLDCWMSQDVNYATKLAYACAPYNLKWIEECLPPQQYEGYRELKRNAPPGMMVTSGEHHGTLQSFQTLSETGIDIMQPDVGWCGGLTTLVEVAAIAKARGQLVVPHGSSVYSHHAVITFTNTPFSEFLMTSPDCSVLRPQFDPILINEPVPVNGRIHKSVLDKPGFGVELNRDCKLKRPYTH
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: YAEH_SHIB3
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: MURQ_GLOVI
Sequence: MDERLPERAHLVTEQVNPDSARLDRLDSPSLVELFCREDERVVPAVRAAAPAIARAIDLTAAALRGGGRLFYVGAGTSGRLGVLDASECPPTFCTDPEQVQGIIAGGTAALTRSVEGAEDDPEAGAAELAGRALSAADVVVGISAGGTAPYVSGALAYARSLGGVTIFVACVPTNQIPERWDIEIRVPVGPEVLAGSTRLKAGTATKLVLNILSTGAMVRLGKTYGNLMVDVAVSNQKLRDRAVRILTTLTELERTAALALLEASGLRVKVALLMHWSNQDPASCATALEAAGGLLPVALEKLSGR
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: ILVC_CUPMC
Sequence: MKVFYDKDADLSLIKGKNVTIIGYGSQGHAHALNLKDSGVNVTVGLRKSGASWNKAVNAGLQVKEVAEAVKGADVVMILLPDEQIADVYKNEVHANIKEGAALAFAHGFNVHYGAVIPRADLDVIMIAPKAPGHTVRSTYAQGGGVPHLIAVHQNKSGAARDIALSYATANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEETKKAMKQCLKDIQTGEYAKSFLLENKAGAPTLISRRRLTAEHQIEEVGGKLRAMMPWIAKNKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GLY1_SCHPO
Sequence: MSGSVTSTTTETRLCPSNQGSAKKYRPWNDFRSDTLTVPTDEMRRIMYEASDGDCVYEEDEDTRKLEVYVAKLTGKEAALFVTSGTQGNQLCIRSHLHQPPHSIICDDRAHIYNWEAGAIGLFTQAIVRPISPKNNVYITAEEIENKLILGNDIHFSPTGLICLENTIKGAVVPLDEVARISGLAKAHKIPLHCDGARLWDAAVASNVSIKEYCSYFDSVSLCLSKGLAAPVGSIIVGPRDFIAKAKWFRKAYGGGLRQSGMLAAAGLYSIQHNFPLLKQVHKYAIEVAEYAESLGIELEVPTQSNMVTLANINVAILCDEAKKSGIILMGPRIVFHIQITPDAVEILKNVLRRTVERQAVETHIVAKPGEFCVGY
What are the official names of this protein?
Probable low-specificity L-threonine aldolase.
What is the protein family that this protein belongs to?
Belongs to the threonine aldolase family.
Protein: CML19_ORYSJ
Sequence: MVAATAEFRRVFSAFDRDADGKISAAELRLCMKAALGEDMSAEEAEALVSSADTDDDGLLDEEEFTKLAVQLEMGDEEERCRGLMEAFRMYEMEGEGRITPASLKRMLSKLGSHQGIEECQTMICRFDLDGDGVISFEEFKIMMDA
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Putative calcium-binding protein CML19, Calmodulin-like protein 19.
Protein: TI214_DRIGR
Sequence: MILKSFLLGNLLSLCMKIINSVVVVGLYYGFLTTFSIGPSYLFLLRARVMEEGTEKEVSATTGFITGQLMMFISIYYAPLHIALGRPHTITVLVLPYLLFHFFWNNHKHFFDYGSTTRNSMRNLSIQCVFLNNLIFQLFNHFILPSSTLARLVNIYMFRCNNKMLFVTSSFIGWLIGHILFMKWVGLVLFWIRQKNSIRSNVLIRSNKYLVSELRNSMARIFSILLFIICVYYLGRIPSPIVTKKLKETSETEERGESEEETDVEIETTSETKGTKQEQEGSTEEDPSFCSEEKEDPDKLDETEEIRVNGKEKLKDKEEFHFWFEKALSTQLFEKKRWNRPLRYIKNDRLENSVRTEMSQYFFSTTCTCGKKIISFTFPPSLSTFWKMIQRNISLCTTEKLSPKDLYNHWVYTNEQKRHNLSNEFRNRMEALDKGSLALDVLEKRIRFCNDENEQECLPKVYDPFLNGPYRGTIKKGYSRPIMDDSIISTEDSTGMVWINRIHGILPNLSDYQEFEDKMDAFNEELVSPDIDHSLNSISELAEESRPSLNLKGLTLLAEQRRLDSENQMKRLKFLFYAVKTDPNDQTIRNKSIGIEEIGKKVPRWSYKLTDDLEEQEAENEEGSTEDPGIRSRKAKRVVIYTYNDQNINTHTSTNTNSDSDQAEEVALIRYSQQSDFRRNLIKGSMRAQRRKTVTWEMFQANVHSPLFLDRIDKTFFFSFDISGMMNPFLRNWMGKDPQFKTSDSEEEEAKEKNKKKKEQKEENERIAISETWDTIIFAQAIRGSMLVTQSIFRKYIILPSLIIAKNLGRMLLFQFPEWYEDLKEWNKEMHVKCTYNGVQLSETEFPKNWLTDGIQIKILFPFCLKPWRGSKLQFHHRDPMKNKVKKENFCFLTVWGMETELPFGSPRKEPSFFEPIFKELEKKMRKVQKKYFRVLKFLKERTKWCLKVSKEKIRWVIKIVLFIKRIMKELAKVNSILLFGLRKGYQPSETGKDSIISNKITHESTIQIRPMGWTNYSLTEKKMKDLADSTTTIKNQIERIKKDKKKIFLTTDINIIPNKTSFDDERSESQKHIWQRSKKRSARLIRKSQYFIKYFIEIIYMDIFLCTINIPRINAQLFLESTKNLIDKYIYNNETNTNKEGIDETNQNKIQFISTIQKSLSILNIRNNNSHIYCDLSFLSQAYVFYKLSQNQEVINKYHLISVLQYHGASPFIKHRIKDCTRGIFDSKSRHKKLPNSRMNEWKNWLKRHYQYNLSQNRWSRLVSKKWRTRVNQRRTIQNKDSKNLDSYEKEKDQFIHYEKENDCAVNSLPSQKEKFKKHYRYDLLSYKYINYEDRKSSYIYVSPLQINGGREIPYNDNTPKPESCYVLGDIAISDYLGEESIMDTGKNPDIKYFKWRILHFFLRKNIDIDTWTDMDTGTNINKNTKNGINDYEKIDKKDLFYFTIHQEIKPPNKKKNFFDWMGMNEEMRYRPISNLESWFFPEFVRLYDTYKMKPWIIPIKLLLLNFHGNENISENKNISENENINGNQKKDLRISSNQKEYLELENRNKEKEQPGQGDIRSDARNQENLESDAQNKKKYVEKDYAESDIKKRRKKRKYKSNKEAELEFFLKRYLLFQLRWDDSLNQRMINNIKVYCLLLRLINPREIAISSIQRGEMRLDVMLIHKDLTLTELIKRGIFIIEPARLSIKRDGQFIMYQTIGISLIHKSKHQTNRECREKKYVDENSFDGSIAQHGKMLVNGDENHYDLLISENILSPRRRRNLRILMCFNSSNENIVDINPIFFNENNVRNSGQFLDEDKCLDTDTNKCIQFKLFLWPNYRLEDLACMNRYWFDTNNGSRFSMSRIYMYPQFRIS
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  May be part of an intermediate translocation complex acting as a protein-conducting channel at the inner envelope.
What are the official names of this protein?
Protein TIC 214, Translocon at the inner envelope membrane of chloroplasts 214, AtTIC214.
What is the protein family that this protein belongs to?
Belongs to the TIC214 family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: MOBA_CLOPE
Sequence: MIKKSAAILAGGKSSRMNYRNKAFLKYEEDYFIERIIKALKDYEEIIIISNNPEEYKEFGLKVFKDIYPSQGPLSGIHSALNHIKNDYCLVVACDMPFINKDVVNYLGNIKEDYEILIPKFQERLQPLCAIYKKSCKDIMEKELINNSNKLIKTCFKFSMKVVEEFPFIEKVHKKEIKNFYNINTVDEYEDLIKKKEI
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RKD4_ARATH
Sequence: MSSSKHSSVFNYSALFLSLFLQQMDQNSLHHLDSPKIENEYEPDSLYDMLDKLPPLDSLLDMEDLKPNAGLHFQFHYNSFEDFFENIEVDNTIPSDIHLLTQEPYFSSDSSSSSPLAIQNDGLISNVKVEKVTVKKKRNLKKKRQDKLEMSEIKQFFDRPIMKAAKELNVGLTVLKKRCRELGIYRWPHRKLKSLNSLIKNLKNVGMEEEVKNLEEHRFLIEQEPDAELSDGTKKLRQACFKANYKRRKSLGDDYY
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Protein RKD4, AtRKD4, RWP-RK domain-containing protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMA_SHEB5
Sequence: MNLAAMDPQTYDTQLEHKRIKLEQAFAQFETPSVEVFASEPANYRMRAEFRMWHDGDDLYYYMFDKVLNEKVRCDQYLPASVLINQMMSALIAELKPNPSLRHKLFQVDFLSTLSGEILVSLLYHRQLDDQWRADATALKAKLSSQFNVNIIGRARKQKIDLDKDFVVESLQVNDKTFLYKQIENSFTQPNAKVSVKMLEWAIDATQNSQGDLLELYCGNGNFSIALAQNFNRVLATELAKPSVDAAQYNIEVNGIENLQIIRMSAEDFSDAMAKKRSFRRLEGIDLDSYVCNTIFVDPPRAGIDPDTLALVQGYERILYISCNPETLKDNLQQLNETHKVTRFALFDQFPYTDHMETGVLLERR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: TILS_MYCGE
Sequence: MASEKQYIAGVSGGSDSMLMLKLYQKKIACVVHVNYNTRSTSLRDQKLVEQYCQKLNIPLVVHTVDPDLVWKKNFQNQARKIRFDQFKKTAKLYQTNKLLLAHHRDDFIEQAKMQLDAKKRAVYYGIKTRCELYGLKIYRPLMKYWKDEIIALCRQDHIPYEIDETNKLPIYKRNEVRLEIEKWSKIEKEQFYIAICAMNKTIAQKLFVLMKKAKKWLLQPDVRELKRFSIIDQKQLIYSYLIYHKINVNGEKIDAILDFIQPSQQKQYRLQNDIFLMVKNQCLALLYKS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VANX_ENTFA
Sequence: MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTKAVALALREAQIHAAALGYGLLLWDGYRPKSAVDCFLRWAAQPEDNLTKEKYYPNIERAELITKGYVASQSSHSRGSTIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGNAEAQNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS
What is the function of this protein?
Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
What are the official names of this protein?
D-alanyl-D-alanine dipeptidase, D-Ala-D-Ala dipeptidase, Vancomycin B-type resistance protein VanXB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M15D family.
Protein: RLMI_SALPK
Sequence: MTESTFPQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLGETIDIVDHQGKWLARGAWSPASQIRARVWTFDKAESIDIAFFTRRLRQAQQWRDWLAKKDGLDSYRLIAGESDGLPGVTIDRFGYFLVLQLLSAGAEYQRAALISALQTCYPDCAIYDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEHGMKLLVDIQGGHKTGYYLDQRDSRLATRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLDLSKAEFVRDDVFKLLRAYREHGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQLLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_CAMJJ
Sequence: MRHLITAKDFNKVEIMELFKEASDFLDEKPRTFLKGKSITTIFFENSTRTLSSFESAARRLGARVLRLDVSRSSSSKGETLYDTAANLDAMSPNAIVVRHANSGVPLILAKHMHCPVVNGGDGKHAHPTQALLDLFTIYNHFQGDVEGKKICIVGDIKNSRVAASNIELLSRFNLDITLVAPPHFMPNTHLKKHYKLDENIIANSDIIMSLRTQTERHNKTVYASLKDYANDFCIQKSLVKDKKLILLHPGPVNRNIDISDEMMSDERTLVLKQVKNGVAIRMAVLKKLILENEG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: FLJL_CAUVC
Sequence: MLNSINTNPGALLALQNLNSTNTELAATQGRINTGKKVANAKDNGAIWSMAKMQSATASSLNSVKDSLQRGQSTIDVALAAGDTITDLLTKMKEKALAASDTSLNTASFNALKADFESLRDQLQKAATNAKFNGVSLADGSTTKLSFLANEDGSNFTVTAQTLSLTGIGLTATSTFTDAATAKTMIATITTSLQTATNKLSSLGTSSVGLDTHLTFVGKLQDSLDAGVGNLVDADLAKESAKLQSLQTKQQLGVQALSIANQTPQTILSLFKG
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin FljL, 27 kDa flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: RPAC2_SCHPO
Sequence: MAAMTDVTDPSSVAMESATEKIIILPGHSADLTSVTFQIQKEDHTLGNSLRYVIMKNPEVEFCGYSIPHPSEAKMNFRIQTAPSTTAVDVLRKGLDDLIDLCDAVTEKFTEQLPRDTSTTMEVDG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.
What are the official names of this protein?
DNA-directed RNA polymerases I and III subunit RPAC2, RNA polymerases I and III subunit AC2, AC19, DNA-directed RNA polymerases I and III 14 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARIR_ECOHS
Sequence: MLEDTTIHNAITDKALASYFRSSGNLLEEESAVLGQAVTNLMLSGDNVNNKNIILSLIHSLETTSDILKADVIRKTLEIVLRYTADDM
What is the function of this protein?
Regulates expression of genes involved in acid-resistance and biofilm formation.  May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition (By similarity).
What are the official names of this protein?
Regulatory protein AriR.
What is the protein family that this protein belongs to?
Belongs to the AriR family.
Protein: RS19_JANMA
Sequence: MTRSLKKGPFCDAHLVKKVETAQAIKDKKPIKTWSRRSTIMPDFIGLTIAVHNGKQHVPVYVSENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y300_BRASB
Sequence: MNAPLDRPANSVDPKLLEILVCPMTKGPLEYDAAKQELISRSAKLAYPIRDGIPIMLPEEARKIG
What are the official names of this protein?
UPF0434 protein BBta_0300.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: VP35_EBOSU
Sequence: MQQDRTYRHHGPEVSGWFSEQLMTGKIPLTEVFVDVENKPSPAPITIISKNPKTTRKSDKQVQTDDASSLLTEEVKAAINSVISAVRRQTNAIESLEGRVTTLEASLKPVQDMAKTISSLNRSCAEMVAKYDLLVMTTGRATATAAATEAYWNEHGQAPPGPSLYEDDAIKAKLKDPNGKVPESVKQAYINLDSTSALNEENFGRPYISAKDLKEIIYDHLPGFGTAFHQLVQVICKIGKDNNILDIIHAEFQASLAEGDSPQCALIQITKRIPAFQDASPPIVHIKSRGDIPKACQKSLRPVPPSPKIDRGWVCIFQFQDGKALGLKI
What is the function of this protein?
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.  Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes (By similarity).  Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes (PubMed:31337716).  Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1.  VP35-NP interaction controls the switch between RNA-bound NP and free NP and thus the switch between genome replication and genome packaging into the nucleocapsid.  Prevents establishment of cellular antiviral state, thereby suppressing host DC maturation.  Acts by inhibiting host RIGI activation both by shielding dsRNA from detection and by preventing PRKRA binding to RIGI.  Blocks virus-induced phosphorylation and activation of interferon regulatory factor 3/IRF3, a transcription factor critical for the induction of interferons alpha and beta.  This blockage is produced through the interaction with and inhibition of host IKBKE and TBK1, producing a strong inhibition of the phosphorylation and activation of IRF3.  Also inhibits the antiviral effect mediated by the host interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR.  Increases PIAS1-mediated SUMOylation of IRF7, thereby repressing interferon transcription (By similarity).  Also acts as a suppressor of RNA silencing by interacting with host DICER1, TARBP2/TRBP and PRKRA/PACT (By similarity).  As a dimer, binds and sequesters dsRNA contributing to the inhibition of interferon production (By similarity).
What are the official names of this protein?
Polymerase cofactor VP35.
What is the protein family that this protein belongs to?
Belongs to the filoviridae polymerase cofactor VP35 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: THIC_CLOK1
Sequence: MNFTTQMDAAKKGIITKEMKVVSQKEGVDVEILRELVAEGKIVIPANKNHKSLDAQGVGQGLKTKINVNLGISKDCANIDMELEKVKTAIEMKAEAIMDLSSYGKTEEFRKRIVEMCSVMIGTVPIYDAVGFYDKELSDISPEEFLAVVEKHAQDGVDFMTIHAGINRETAKVFKRNKRLTNIVSRGGSLLYAWMELNNKENPFYEYYDKVLDICARYDVTISLGDACRPGSINDSTDASQIKELITLGELTKRAWEKNVQVIVEGPGHMSLNEIAANMQLEKKLCHGAPFYVLGPLVTDIAPGYDHITSAIGGAIAAANGADFLCYVTPAEHLRLPNLEDMKEGIIASKIAAHAADVSNNIKGAKEWDYKMSEARKELNWEKMFDLAIDPEKARRYRRESTPEHEDTCTMCGKMCAVRNMNKVMEGKNINILREED
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RECR_ACAM1
Sequence: MSTVYTRPLARLVEQLQRLPGIGPKSAQRLALHLLKRPTAEVEALANALIEAKQQVGFCSVCFHLSADPVCDICRAPSRDKTVICVVADSRDVIALEKTREFKGQYHVLGGLISPMDGIGPDQLNVQPLIRRVHQTKTQEVILAINPSVEGETTTLYVGQLLKPFTRVTRIAFGLPMGGDLEYADEVTLARALEGRRDLD
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: CHSB_IPOTF
Sequence: MSTAVTMLTDTWSRRAKRFEIEGYAKILAIGTATPANWVDQTTYPDFYFRITNSQHLLEHKEKFRRICNKSNIRKRHMVLTEELLKKNPNLCTYNDASLNTRQDILVSEVPKLGKEAAMKAIKVWGRPISEITHLVFCTTSGVDMPGADFQLTKLLGLNSSVKRLMMYQQGCNAGAAMLRLAKDLAENNKGARVLVVCSEVMLSVFRGPSLQQEDNLLAQCLFGDGSAAIIIGTDPRPGLETPLFELISAAQTIIPDTDSHLKLHVREMGLTFHCSKAVPTFITQNVEDCLVKAFEPYGISDWNSIFWVLHPGGNAIVEGVEETLGLAPEKLRASRDVLSEYGNLTSACVLFILDEVRKKSKKDEQ
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase B, Naringenin-chalcone synthase B, CHS-B.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.