PharMolix/UniProtQA huggingface dataset:
Protein: DBP4_CANGA
Sequence: MAKKHRYTTVQRKQERQKEEEYIKELEQRIQDYDVKNNKAVFFKDLPISKSTLKGLNEASFIKMTDIQRDSIVTSLQGHDVFGTAKTGSGKTLAFLVPVLEKLYRERWTEFDGLGALIISPTRELAMQIYEVLVKIGSHTQFSAGLVIGGKDVNFELERIAKINILIGTPGRILQHMDQAVGLNTSNLQMLVLDEADRCLDMGFQKTLDAIVGNLPPDRQTLLFSATQSQSISDLARLSLTDYKKIGTIDSSEDGPATPKTLQQSYIIADLADKLDVLYSFIKSHLKTKMIVFFSSSKQVHFVYETFRKMQPGISLLHLHGRQKQRARTETLDKFFRAQQVCLFATDVVARGIDFPAVDWVIQVDCPEDVDTYIHRVGRAARYGKKGRSLIILTPQEEAFLTRMAAKKIEPGKLTIKQSKKKSIKPQLQSLLFKDPELKYLGQKAFISYVKSIYIQKDKEVFKFDELPTEEFANSLGLPGAPRIKIKGMKAIEQAKKLKNTSRSLLSLSKANDDGEINDKKDKQVRTKYDKMFERKNQTILSEHYLNITKSQAQEDEDEDFITVKRKDHELKEEDLPQLTVPTSRRAQKKALSKKASLSTKGNATKMVFDDEGQAHPVYELEGEEEFHKKGDAEEQKKEFLSKEAEIMADRDVSDKIIQKEKKQEKKRKRLEAMRREMEAAYADEYSDEDEEGGNVAYLGTGNLSDDMEEYSSDEESRKTKKSKTVDYRFDKKNKTISEDTDIMEIQEPETIEDLESLTARLIEG
What is the function of this protein?
ATP-dependent RNA helicase required for ribosome biogenesis.  Involved in the release of U14 snoRNA in pre-ribosomal complexes.  Required for pre-rRNA cleavage at site A2 (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RM48_MOUSE
Sequence: MSGTLGKVLGVWTNTVSKQGFSLLRFRSLGENPIFSAGGILWTSRHYKTKPTHGIGRYRHLVKVQEPKKKKAKVELRAINVGTDYEYGVLNIHLTAYDMSLAESYAQYVHRLCNRLSIKVEESYAMPTKTMEVMRLPDQGNKMVLDSVLTTHERVVQISGLSATFAEIFLEVLQSNLPEGVRLSVREHTEEDFKGRFKARPELEELLAKLN
What are the official names of this protein?
39S ribosomal protein L48, mitochondrial, L48mt, MRP-L48.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL48 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: V1BR_MOUSE
Sequence: MDSEPSWTATPSPGGTLFVPNTTTPWLGRDEELAKVEIGILATVLVLATGGNLAVLLILGLQGHKRSRMHLFVLHLALTDLGVALFQVLPQLLWDITYRFQGSDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPSQSTYPLIAAPWLLAAILSLPQVFIFSLREVIQGSGVLDCWADFYFSWGPRAYITWTTMAIFVLPVVVLTACYGLICHEIYKNLKVKTQAGREERRGWPKSSSSAAAAATRGLPSRVSSISTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDENAPNEDSTNVAFTISMLLGNLSSCCNPWIYMGFNSHLLPRSLSHRACCRGSKPRVHRQLSNSSLASRRTTLLTHTCGPSTLRLSLNLSLHAKPKPAGSLKDLEQVDGEATMETSIS
What is the function of this protein?
Receptor for arginine vasopressin.  The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.
What are the official names of this protein?
Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAPA5_MYCBP
Sequence: MFPGSVIRKLSHSEEVFAQYEVFTSMTIQLRGVIDVDALSDAFDALLETHPVLASHLEQSSDGGWNLVADDLLHSGICVIDGTAATNGSPSGNAELRLDQSVSLLHLQLILREGGAELTLYLHHCMADGHHGAVLVDELFSRYTDAVTTGDPGPITPQPTPLSMEAVLAQRGIRKQGLSGAERFMSVMYAYEIPATETPAVLAHPGLPQAVPVTRLWLSKQQTSDLMAFGREHRLSLNAVVAAAILLTEWQLRNTPHVPIPYVYPVDLRFVLAPPVAPTEATNLLGAASYLAEIGPNTDIVDLASDIVATLRADLANGVIQQSGLHFGTAFEGTPPGLPPLVFCTDATSFPTMRTPPGLEIEDIKGQFYCSISVPLDLYSCAVYAGQLIIEHHGHIAEPGKSLEAIRSLLCTVPSEYGWIME
What is the function of this protein?
Catalyzes diesterification of phthiocerol, phthiodiolone, and phenolphthiocerol with mycocerosic acids, the final step in the phthiocerol, phthiodiolone and phenolphthiocerol dimycocerosate esters (PDIM) synthesis.  Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (mas) onto the substrate alcohols.
What are the official names of this protein?
Phthiocerol/phthiodiolone dimycocerosyl transferase, Acyltransferase PapA5, Phthiocerol/phthiodiolone O-acyltransferase, Polyketide synthase-associated protein A5.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase PapA5 family.
Protein: HEMH_HELPJ
Sequence: MNLINEKLNNLENSATKSPKEAVVLLNMGGPNSLYEVGVFLKNMFDDPFILTIKNNFMRKMVGKMIVNSRIEKSKKIYEKLGGKSPLTPITFALTERLNELDPSRFYTYAMRYTPPYASMVLQDLALKEIESLVFFSMYPQYSSTTTLSSFNDAFNALKSLETFRPKVRVIERFYADKKLNEIILNTILSALNNCKSQDFVLIFSVHGLPKSIVDAGDTYQQECEHHVSLLKELMQQKNIPFKEVLLSYQSKLGPMKWLEPSTEELIEKHRKSNIIIYPLAFTIDNSETLYELDMQYRLMAERLAVKEYLVCPCLNDSIEFAKFIIELVKNLKSE
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_SHESW
Sequence: MEDLQLVLFILGAIAIVAVLVHGFWSIRRQQPKSLKDSPMGNFYKQQADKESPPKRVDADGFDADGIGAVRVRKVGESNPHETPPISPYLKQDVKAEPKPLFKHTTSTEIKQEPVPQPDFSLQSPLATEQQRGAKVSRQEPVLNGHVPPLGQSHAAMVAQKALEQEKHAQSTTVPTQTALFDEDAYLENTESEDEYAEETVDEGLDEPRDVLVLHVVAKEGQQLNGAELLPCFLTLNFKYGDMNIFHRHVDNAGNGKVLFSIANMLKPGVFDPDNMEQFSTQGVVFFMTLPCYGDALMNFSIMLNSARQLADDIDAVVLDGQRQPWGEFTKQDYLHRIRANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: GATB_BORPD
Sequence: MNWEIVIGLETHTQLSTDAKIFSGSSTRFGAAPNTQANVIDLALPGSLPVMNRGAAERAIRFGLAVGGKVAPRSVFARKNYFYPDLPKGYQISQYELPVVLGGSLSFFVGEQEKTVNLTRAHLEEDAGKSLHDDFALASGAPASGIDLNRAGTPLLEIVTEPEMRSAAEAVAYARALHSLVVWLGICDGNMQEGSFRCDANVSVRPVGQKEFGTRTEIKNVNSFRFLERAILFEARRQIELIEDGGTVVQETRLYDADRDETRSMRSKEDAHDYRYFPDPDLPPLVISPEWVEEVRANMPELPAALRERFQRDYGLSAYDAAQLSASRGLASYFEDVARALPAGQAKQAANWIMGEVTATLNREEKDIADAPVQAPALAALIGRIIDGTISNKIARDVFSAMWAGEHGGQPDAIIEARGLKQISDTGAIGAMIDEVLAANPAIVAEYRAGKQKAFNSLVGQIMKAAKGKANPQQVNELLKQKLEG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: AROK_SHEPA
Sequence: MAEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFRIRETQVVADLTEKQGIVLATGGGSIQSKEIRNNLSARGIVVYLETTIDKQVARTQRDKRRPLLQVDDPREVLESLAEVRNPLYEEIADVIVKTDEQSAKVVANQIIEQLGF
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_PSESM
Sequence: MSLIVSDRFRIVVGLGKSGMSLVRFLANRGVSFAVADTRENPPELATLRRDYPQVEVRCGELDVDFLCRADELYVSPGLALATPALQQAHARGAKLSGDIELFARYAKAPVIAITGSNAKSTVTTLVGEMAAAAGKRVAVGGNLGTPALDLLSDDVELYVMELSSFQLETTDQLNAEVATVLNISEDHMDRYSGLPAYHLAKHRIFRGARQVVVNRQDALSRPLIGEGLPCWTFGLNKPDFHGFGLREENGEKFLAFQFENLMPVSELKVRGAHNQANALAALALGHAVGLPFDAMLSSLREFTGLEHRCQWLRERNGVDYYNDSKATNVGAALAAIEGLGSDIGGKLVLIAGGDGKGADFSGLRAPVAKYCRAAVLLGRDAELIAQALGDAVPLIRVDTVQAAAERSAELAQRGDAVLLSPACASLDMFKNYEERGRVFAQAVECLS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YETL_BACSU
Sequence: MELKHLPKYKHITEHAETYANIDAGSLELFLSLFDISKKMNHVMEHYFAGRGLSEGKFKILMLLFDAKDHRLSPTELAKRSNVTKATITGLLDGLARDGFVSRRHHTEDKRKISIELTTEGKARLEQFLPGHFSKISAVMENYSDEEKDMFVKMLGDLFERLSVFKD
What is the function of this protein?
Negatively regulates yetM expression and its own expression (PubMed:19329649).  Binds specifically to corresponding single sites in the divergent yetL and yetM promoter regions, with higher affinity to the yetM region (PubMed:19329649).  Recognizes a 28-mer operator of double-stranded DNA that contains a palindromic sequence (PubMed:35367827).
What are the official names of this protein?
HTH-type transcriptional repressor YetL.
Protein: GALT_CLOPS
Sequence: MYNLNALIDRLIEISKNNNLIEDMDTVYTRNRLLSIFNENSYTPCEEKLTLSFHETLNELINIAIEKKIIENALYSKDIFSSDIMNIFLPTPSLINKEFYKRYAISPKESTDYFYSLSKSSNYIRTDRIAKNINFKAPSKYGTMDITINLSKPEKDPKEIALARNSVKSNYPKCLLCIENEGYEGTVTHPDRANHRMIRLSLNDRTWMLQYSPYLYYNEHCIILSEDHVPMKIDISTFKNLLSFVDKFPHYFAGSNADLPIVGGSILSHEHYQGGNHRFPMNDAKKLFDFSIDGFEDVECEAIKWPISTIRLRGENIDSLVLASDLILKKWRDYSDETLDILSYSNSEMHNTITPMVRKEDGKFVVDLSLRNNRTSKEHPLGIFHPHEEVHHIKKENIGLIEVMGLAVLPGRLLKELEKIKEYLRDEISLDNIEEYHRPWALELKKKFDYLKSATDLNDFVNKELSNKFVSVLEHCGVFKLNEEGLEGFKRFTNSLNN
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMT1_SERL9
Sequence: MVYFATSAENSKTSYKVDLSHHLSRETRARQPNPIKTIWKIAQTKVGTINMGNGDPHNTLYPISKIDFVVPSLDQPNPVQAWKEGNSKTDIISSYKDESCALSLKTAFAYGTGAGLQQVRGVLADLNNRIHSPPNHTVSLSLGNADSLTKCFRLFGDPGDSFLCEEFTFSPMTNAALPLGIKWEPIKMDKGGLIPADMDKILTNWDERTQGRRPHVLYTVPCSQNPTGSTLPFERRKSIYEIARKWDIIILEDDPYYFLQYGLNVDQFIVEQHGFTRALASVLPRSFLSMDYDGRVVRLDSFSKIVAPGMRLGWVTANNFFAEKLDSLTDSSSQHPHGFGQAFIAELLGDGGWGLDGFMKWTKSLCDEYQRRRDLFMDVFRREVGINGFATAEVPKSGMFVWIKINLEHHARYRVVKESNGDPRTNTAALMDELFRTLLDSGLVLIPASTFAITGSLSPPSGDCILDVSICIDGVGAIAELPLSIFQRVNYFRATFVGTDETICDGLKIFGRTIEQFFCF
What is the function of this protein?
An L-tyrosine:2-oxoglutarate aminotransferase (probably amt1) and atromentin synthetase nps3 catalyze consecutive steps to turn over L-tyrosine into atromentin, which represents the generic precursor molecule for the entire terphenylquinone and pulvinic acid family of pigments, which are widely distributed secondary metabolites in homobasidiomycetes (Probable).  The first step catalyzed by amt1 converts L-tyrosine in to 4-hydroxyphenylpyruvate (4-HPP).  Adenylation of two 4-HPP monomers by the nps3 adenylation (A) domain, covalent tethering of the monomers as a thioester and oxoester onto the nps3 thiolation (T) and thioesterase (TE) domains, respectively, and symmetric C-C-bond formation between two monomers catalyzed by the nps3 TE domain leads to atromentin.  Follow-up products of atromentin in S. lacrymans include atromentic acid, xerocomic acid, isoxerocomic acid and variegatic acid (By similarity).
What are the official names of this protein?
L-tyrosine:2-oxoglutarate aminotransferase amt1, Atromentin biosynthesis protein amt1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: FUR_BRUA2
Sequence: MNKPYTKPDYEQELRRAGVRITRPRRIILNILNETEDHPDALEIFRRAVEEDDSISLSTVYRTMKLLEERGAIHRHAFAGGPSRFEQASGAHHDHIIDMDSGDVVEFHSDKIEKLQEEIARSLGFEIVHHRLELYCKKLKS
What is the function of this protein?
Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.
What are the official names of this protein?
Ferric uptake regulation protein, Ferric uptake regulator.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB1_PLETE
Sequence: MEFSVKNKNLLIQNLVEIQQQSFNELLCVGLKRQLLQLNFIENKTRNIKLIFHAKNYKFILPEITPKEAVLKSKTFASALFIPVEYRAKNSIGLYWVLLGHLPFMTKRGHFIINGVPRVVLNQMVRSPGLYYKTTANPQNVSNQVSINDSSHTSPVFYSDIIPNRGTWLRLEIDRKKNIWIRMKRVDKIPMMLFLQALGYDLHCIEKLLYSRKFLNCDYLLNTDHPADSNSALKKIKVEIEQQKVLKLAALEALDDDDPDIAKQLDYIEKTTTPEMGKDFLFQSFFNPASYDLSPIGRFQLNKKLNLSIPSDYTVLTEFDIYFATKELIKRATTMSNSDDIDHLQTRRIRSCGELLEIQLGEGIERLQKTIIDKINNTNLKKFAKHSSTYKRGTSSSIYRQDRQVINTDKNSKFLKNNLPTKFNRITLEPNLLPNGTSFIHKNNKLNQVSSNKLKLLSKKLIYLNLLINQKFIIAKLKSANLLANKSSFDKFLIHLVDESPRQKFVKNKTGLYHKFIPTPEIYIVEPNLNLVDMKSQQKFNLLKMDLYKVGLAESFLKSNLNNLNIYLQMCLRKPNTYFRDISKICSAQITQQLKQKSFLKLLLINPRLISQNNLLVLNRAVNFLKKIQFNLKDSPNLNDYQNFEINKLKAHIFKCQIKTQNNLTCCKYIYIKTKFNYINLPIKQFFFTKRFLITEQKLLLGGKFINSNLALTSLLKLHKFSEVVSNSFLIYNANNPNPNPTSIMSMIRPVNKSEIYRQLNRRFVRSRLQLNVLKSELTNSHSQLIKANNDPIDRELSIQILKQDVQKSNPFNKKGIYNQRFINKKFLDTSQFIDQELLHFLKTHKIFLDRQLTSLKTKQQNEKLKFIKWKKLRNFKNALKNPIQNLITTNAINGALQELFGLNPLSQFMDQINPLSEITHKRRISSMGPGGVNRDNASMDVRSIHPTHYGRICPIETPEGHNAGLVNSPTIYARINNYGFLETPFFKVNSGQIQAKAFYLNAQKEQKFKVSPPDLSCSELQFLPLGPTKIESEVPMRKDFKFQRMAATQIEFIGISPLQMISVATSLIPFLEHDDANRALMGSNMQRQAVPLLIAERPVVGTGLEGRVIADSSYIMQTKQSGVISYVSNEQVIVQTFHLNN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta N-terminal section, PEP, Plastid-encoded RNA polymerase subunit beta N-terminal section, RNA polymerase subunit beta N-terminal section.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TIG_CUPMC
Sequence: MSNVIENLGKLDRKVTLAIPKAEVQKETQERLARLSKTVKMSGFRPGKVPMKMVEKQYGQQVEFEVRFDKAARKFFDITQAQEVKVAGQPKFDIKTEGVADDELAFEATFEVYPEVKIGDLASAEVTRTKTEIGDAEIDKTVDILRKQRVHFHARGDAGAHGDGGADVAAQNGDRVTLDFVGKIDGVEFAGGKAEDFVYVLGEGRMLPEFETATLGLKVGESKSFPLTFPADYHGKEVAGKTAEFTVTLKKVEWAHLPEVDDAFAKSLGIADGSVEKMRADIRENLEREVKRRTHSMLKDQVMEALLKVSELDVPKALVEQDQERLVEMARRDLEQRGMPNAKDMPIPAEMFTQQAERRVKLGLILAEIVKANGLEAKPDQIKAEIEDFAKSYEDPKEVMRWYYGDQQRLAEMEAYVLENNVVNFVCDKAKVADKTVSFEELTAAPAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RL331_MYCGI
Sequence: MTRNEIRPIVKLRSTAGTGYTYVTRKNRRNDPDRIVLRKYDPVVRRHVDFREDR
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS9_SALCH
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: YBEY_PSEA6
Sequence: MSAIVDLQVASDAANLPSADDFQRWLNAVLAHQQLSEHELTVRIVETQESQELNLTYRGKDKPTNVLSFPFEAPPGLSLNLLGDLVVCADVVAHEADEQHKKLHHHWAHMIVHGALHLLGFDHINDDEAKEMEALEVDILKQFSIDDPYQDQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_AGRRK
Sequence: MGFTTSSVTDAIAALDERSKEIFRRIVEGYLENGEPLGSRNLSRLLPMSLSPASVRNVMSDLEELGLIYSPHISAGRLPTQIGLRFFVDAFMQVGDLSAEDRATIDRQVRGSNRDQPMESVMTEASRMLSGISRGAGLVITSKNDPVLKHVEFIRLEPTKALAVLVGDHDQVENRIIELPAGITSSQLTEAANFLNAHMTGQTLPDLRRQLLTLKESVRHELDTLSHELVERGIAVWSGGEDEGKPTQLIVRGHANLLTEVGGAEDLDRLRLLFDDLEKKDSLIEILNLAESGPGVRIFIGSENKLFSLSGSSLIVAPYRDDDDRIIGAVGVIGPTRLNYARIVPMVDYTAQLFSRMSRPGL
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: PANB_DESPS
Sequence: MRKTVVDIIAMKAAGQKISMLTAYDASMSALLDQAGIDILLVGDSLGMTVLGYDSTVPVTMADMVHHMAAVRRGAPDAFVVGDMPFGSYQTGARDAVLNAMRLLKEGGCDVVKLEGGEVVCPVVKAIVDAGIPVMGHLGLTPQTAAVLGGYKVQGRDMEAARKLFADAKRLEEAGVCGLVLECIPAGLAEVVTASIAVPTVGIGAGKGCDGQVLVINDMLGLFEKFTPKFVKHYAQLAPLVRQGVENYIGEVRAGAFPEAEHTFTSSCDYKVLLSGDDQ
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MG101_CANPC
Sequence: MLHSTKLVFRATPQALCFPVRSYSRYVRTVPKTASAKTTSKLAPSITTEDEVAEQDPSLQEPQSATSTASFAFHDAPPETRSVLNSSTNNNIDWSDSYHGLGSQPFSREIADILLAPIKDQDIEIKPDGLLYLPEIKYRRILNKAFGPGGWGLVPRTESLITKSQISREYGLICHGRLISIARGEQDYFGGEEKVTTALEGCKSNALMRCCKDLGIASELWDPGFIRKWKAKYCEEVFVEHVVNKKKKKLWKLKSNKKIEYPYKQL
What is the function of this protein?
Plays a role in the replication of the mitochondrial genome and the maintenance of its telomeres (PubMed:26743001).  Able to catalyze strand annealing and D-loop formation (PubMed:26743001).  Binds a wide variety of DNA substrates (PubMed:26743001).  Exhibited the highest affinity for DNA molecules carrying 3' ssDNA overhangs (Y-form, 3' FLAP, 3' overhang) and for substrates with complex structures (X-O and Fork) (PubMed:26743001).  Forms homogeneous ring-shaped structures at the ssDNA native telomeres ends (PubMed:26743001).  Oligomers seem to bind to the ssDNA as a filament until they reach the double-stranded region and induce the formation of bends and loops within the double-stranded part of the molecules (PubMed:26743001).
What are the official names of this protein?
Mitochondrial genome maintenance protein MGM101.
What is the protein family that this protein belongs to?
Belongs to the MGM101 family.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid.
Protein: UPA1_USTMA
Sequence: MTIPDPANIIHNDAGTASPHHIWADVGDSTSSSQHEATRSRSDDANGGASASMHAPQHVKANRAAQPTYDSSDLPSFGLSARLTRDSSSFGSKPSSSASDSRRPKFAPYEAENLWATSSTTSHPSKASQSTLSPNASVFKPSRSLQPNHFEPHAVANVHDFDDPLNSAYSSDTVSPRPDHAPLDHEQPQQPSALDPVAVSKVEEQRGDHSIPHQNGLVSAQAQTASDAVSTSKYTTEAADQEEDQDDFVYPGADSPSSGQAAVQDEQQAVTDSQTTKSLTKQESDPEASSTSLSAPAEAEHIVVGSAAEQSLTSSAPAETAVHIDYDTLAQLCSRGPLSDLQSFFHTAQESGLSMFSLSNDPNPGNGLVPLHFAAKDGKTDIVRWLITQAGAIVEMEDREGETALHKAAMAGKLSVASLLLSHGADANAQDADGWTALHNACSRGYLDLVRLLVDRGHAQIDVQGGRGAWTPLMNAASKGHLPVVRHLTAKYHADPFVRNAAGETAFDVAAATFEVYICEILERYEAERWNASKFTTSSPSRSGAIVPGRGPYEPLALHTTIPVILHENQRLDTRLQTLALNGGKPRWSSSSAARAHKPDRRSPSSMPPGPLAPSRTRHVPMRQDDVGLPTRSLPYKLRLRSRVGPAAARRRAAALAAQHTPNPQDCHDDDLASTPTPESVLQARRGTSSVNGASAQHADAESSHFWLCEWQLDTTHPLVDVEHGWQYAQSFDALDDKWSSQPPPPLERLLEGRGLSASVTRAITGGAGFANAQAEQEISSSSWVRRRRWIRVLRRRLDIEFGDDLEACEGATGAGAEHLVLSSESQSNGDGSHGLSTAAIMAAQEAAKSECSQLGPDADYVSRAKALAGPSAASGATPADAMGADRDELARRIARLVMANTELRAAFEDDDVERRSRAEELRKEYALQLGQLREAAGLDEDEDEDAADDDDDEFIYPNSYKDDGASVFTRLVNGETSGTLSRPSLSQRQSSAASMLRNSVAPSEAGTSLAAARSADLAANREFRVPTNEAPNKVVLRHGPTMREQNLQPQWQRDEEAKDCIGCGRHFTFFLRKHHCRRCGRIFCDACSSKRAQLRMAELVVDPSLPSMAASEVLAPTRVCNGCHAELQLPPQLQNMRGADAMMAASRSRGADEVSGRSILETQLEDGAFRSTLAPPSDVSSRASELTECPVCSTTLSALGGSEEQEAHVRNCLENGGGGSMQGGRYLVYKLPEDSPIVGKECSICMEDFVANSTIARLPCLCYFHRGCIDSWFKRGRECPVHARDW
What is the function of this protein?
FYVE zinc finger domain protein that functions in endosomal targeting and transport of mRNAs, as well as associated ribosomes (PubMed:25985087, PubMed:28422978).  The endosomal mRNA transport regulates polarity of the infectious hyphae by transporting a broad spectrum of cargo mRNAs from the nucleus to cell poles (PubMed:25985087).  Involved in chitinase CTS1 secretion (PubMed:25985087).  Dispensable for general endosomal functions but crucial for endosomal recruitment of RRM4 (PubMed:25985087).
What are the official names of this protein?
FYVE zinc finger domain protein UPA1, PAM2 domain-containing protein UPA1.
What is the protein family that this protein belongs to?
Belongs to the UPA1 PAM2 domain-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Endosome. Note=Shuttles with endosomes along microtubules (PubMed:25985087). the FYVE domain mediates endosomal localization and endosomal targeting is crucial for its function during polar growth and CTS1 secretion (PubMed:25985087).
Protein: ACP_BACCQ
Sequence: MADVLERVTKIIVDRLGVEETEVVPAASFKEDLGADSLDVVELVMQLEDEFEMEISDEDAEKIATVGDAVTYIESHL
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_RHIET
Sequence: MHLTAENLAARRGEDMIFINISFYLAAGEALVLTGRNGSGKSTLLRVVAGLLKPEKGTVIFGDKESPEGQHPGEVSHYLGHRNAMKNELTVAENLDFWRHFLRSTCSSADLSVEDATEAVGLSGISHLPFGYLSAGQQRRFAFAKLLVAHRPVWILDEPTAALDASADRLFAGLIEAHLAKGGIVLAATHQPLGLKNAQELKMTGFAGVDRGVWG
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FYV7_ASHGO
Sequence: MVGVGKKFTKESKVREIQKNLHKRAKLKRQYLKTLEQEGYEVPEEQKRQKPSFEQRKGEKKQKVDEKKEHARRRKREQKEEMEAKRQRELDELERAKVRQVERERRNKRIQQKTRSGQPKMGPRINDLLDKIQKDTTYTS
What is the function of this protein?
Involved in the processing of the 20S pre-rRNA.
What are the official names of this protein?
rRNA-processing protein FYV7.
What is the protein family that this protein belongs to?
Belongs to the FYV7 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TRUA_ERYLH
Sequence: MTRFALTLEFDGTPFMGLQRQKHGPSVQQAVEEAARATLNQDITLHSAGRTDTGVHALGMRSHFDAETDLTPFRLMGGLNAHLRPHPIAVTNCEIMPEDWHARFACIGRSYVYRIINRRAPLTIDRKRAWQVPQQLDHEAMQRAAQLLVGTHDFTTFRSTQCQAKDPVKSLDRLEVERDGDEIRVHAEARSFLHHQVRSMVGCLKLVGQGTWREEEVEEALLARDRQRLGLNAPPHGLYFVAAEYPR
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: Y070_RICCN
Sequence: MILLMCLTSYRKNRRAYKKEFEAMLKCEEGDLSCPFIIKTQNLGFFVDISS
What are the official names of this protein?
Uncharacterized protein RC0070.