PharMolix/UniProtQA huggingface dataset:
Protein: EIF3H_RAT
Sequence: MASRKEGTGSTATSSSSTGGAVGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKANITFEHMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIIKYNTYMRNSSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPHQAPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYSN
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h, Eukaryotic translation initiation factor 3 subunit 3, eIF-3-gamma, eIF3 p40 subunit.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOSZ_PSEFL
Sequence: MSDKKDQVPGAVEAPRGVSRRSFLGTGAVTGAVLAGATALGAGTFTRESWAAAAKEAKSKIHVGPGELDEYYGFWSGGHQGEVRVLGVPSMRELMRIPVFNVDSATGWGLTNESKRILGDSAKYQNGDCHHPHISMTDGKYDGKYLFINDKANSRVARIRLDIMKCDKILTVPNVQAIHGLRLQKVPYTKYVFANAEFVIPHPNDGHTFDLQDKNSFTMFNAIDAEKMEMAFQVIVDGNLDNSDADYTGKYAASTCYNSEKAYDLGGMMRNERDWVVVFNILRIEAAIKAGKFITLDGSKVPVVDGRKTDGKDSEFTRYIPVPKNPHGLNTSSDGKYFIANGKLSPTVSMIAIDRLDDLFNDRYKDPREVIVAEPELGLGPLHTTFDGRGNAYTTLFIDSQVVKWNMDEAIRAYKGEKVNYIKQKLDVQYQPGHNHASLTETSEADGKWLVVLCKFSKDRFLPTGPLHPENDQLIDISGEEMKLVHDGPAFAEPHDCILARRDQIKTQKIWNRNDPFFADTVALAKKDGINLETDNKVIRDGNKVRVYMTSMAPAYGLTEFTVKQGNEVTVTITNIDQIEDVSHGFVMTNHGASMEISPQQTSSITFTADKAGLHWYYCSWFCHALHMEMVGRMLVEKA
What is the function of this protein?
Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide.
What are the official names of this protein?
Nitrous-oxide reductase, N(2)OR, N2O reductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: G6PI_ECO5E
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_CHLL3
Sequence: MYAYFRGRVVSVLPEEAVLEVSGIAYRFLISTGTSRSLPQAGNEAILYTHLSVREDALQLYGFSSEEEKQLFRLLLLVSGVGPKLALAVLSGLPVAEVHEAILANAPERLFGVTGVGRKTAARIILELRDRILKLSPPGAAATPAGAVQCGIREDATNALLTLGFSRTAAQQAVAGVLEANPGGSVEDVVKSALLAMHNR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RS8_LACCB
Sequence: MVLTDPIADYLTRIRNANMVRHESLVVPASKMKKDISEILKREGFIRDYEVIDDDKQGVIRIFLKYGKNNERVISGLKRISKPGLRSYVKSDAVPKVLNGLGIAIISTSEGVITDKEARAKNVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NRDR_CUPTR
Sequence: MKCPFCGHSNTQVLDTRMSEDGDAVRRRRRCEACDRRFTTYERIELFFPAIVKKNGSRVDYARAKLKDSMRLALRKRPVSAEAIDEAITRIEEKLLALGEKEIPSSQVGELVMRELRKLDKIAYIRFASVYRSFEDVSEFSDVLAEVTAGSGKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MIRO1_DANRE
Sequence: MRKDVRILLVGEPKVGKTSLIMSLVSEEFPDEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLYQEITKANVICIVYSVNNKKSIEKVTSHWIPLINERTDKDSRVPLILVGNKSDLVEHSSMETILPIMNQYSEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYSPEEKEMKPSCIKALTRIFKISDLDNDGILNDNELNFFQRTCFNIPLAPQALEDVKNVVRKNMTDGVKDNGLTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLELTQEYLFPLFKIPPDCTTELNHNAYLFLQSVFDKHDKDRDCALSPDELKDLFKVFPYMPWGPDVNNTVCTNEQGWITYQGYLSQWTLTTYLDVQRCLEYLGYLGYSIIQEQESQAAAITVTRNKRIDLQKKQTQRSVFRCNVLGARGCGKSGFLQAFLGRNLVRQKRIREDHKSYYAISTTYVYGQEKYLLLHEVLPDVEFLSEADLACDVVCLVYDISNPRSFEYCAKVYKKHFMDSKTPCVIIAAKSDLHEARQYYSLSPLDFCRKHKLHPPQLFTCNTTEAPSKDLYTKLTTMAMYPHMTQADLKNSTFWLRASVGATVFAVLGFAMYKALLKQR
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking.  Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
What are the official names of this protein?
Mitochondrial Rho GTPase 1-A, MIRO-1-A, Ras homolog gene family member T1-A.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: SEPF_BACCZ
Sequence: MSWSKVKYFFFDTPEEKEAAQYSYEKEQTDMKKQQDPPEQQDVTFPKAQPKQNVVSIETAKQSSKVVLLEPRTYSEAQGIADHLKGRRAVVINLQRMSTDQAVRIVDFLSGTVYAIGGDIQKIGPKTFMCTPENVDIVGAISELFGEEEDTNIKRW
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: GRIFN_HUMAN
Sequence: MAVQSKAFCAGGLAPGWKLLVQGHADSGEDRFETNFLLETGDIAFHIKPRFSSATVVGNAFQYGRWGPEQVSSIFPLAPGEPFEIEVSWDAEHFHVYAPEHKVLQFPCRQRPLGATTRVRVLSDHCLAQVELAKRGLSWGDRGY
What are the official names of this protein?
Grifin, Galectin-related inter-fiber protein.
Protein: COXX_RICFE
Sequence: MSSLVTPINLDKINHSQSTVKDYILLMKPRVMSLVIFTGFVGIWLAPYSVHPFIAGIAVVCIALGAGSAGAINMWYDRDIDSLMKRTQKRPIVRGAIEPDEALSFGLITGFFAVFFMALCVNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGALPPVIGYAAVSNTISLESIILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPAVKGNLYTKKQILIYSILLFIVSLMPFFIGMNNFIYLITSGILGLVFLYYSGSLFYDTPDNKQAKRFFAYSIFYLFFIFLLLSSTSTISLIS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y286_PROMM
Sequence: MEPLTHPLLDEATVSQLRATLLADETSWQDGRKTAGYQAAEVKNNLQLDRNSKTAKENSQLVIKQLESDPLVKSFALPRHIHGVMFSRSGIGQGYGMHVDNAYMSSGRSDLSFTLFLNEPESYEGGALCIQTLQDSKQVKLPAGQVIIYPSTSLHAVETVTAGERLVCVGWIQSYISSNEDRTILFGLNAGARALLAEHGRSPELDLIFQAYTNLLRRLGS
What are the official names of this protein?
PKHD-type hydroxylase PMT_0286.
Protein: MSRA_BRUSI
Sequence: MSFFDSYRKKMQMPSKEEVLPGRVQPIPTAAAHFVSGHPLKGPWPDGMKQVLFGMGCFWGAERLFWQVPGVYVTAVGYAGGITPNPTYEETCTGLTGHAEVVLVVYDPKVVTLNELLALFWEEHDPTQGMRQGNDIGTTYRSVIYTFNAVDRAVAEKSRDAYSQALASRGLGPVTTQIADAPDFYYAEDYHQQYLAKNPDGYCGLRGTGVSCPIPLAH
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: YLB9_CAEEL
Sequence: MSTGTPHYAADRSKSRKSNNNRSIPFRTPTTQKVVKTSIRLGPVNPPTPTRNTQGGHGFSAEFLEYRRRRQERHTVRLAKLPNETLIIGGANPFDARNVPEAIKKFRDLVDEKIGDKVHKKDANKSKIVFREEEEETQNGTITID
What are the official names of this protein?
Uncharacterized protein C34E10.9.
Protein: COMB_CLOBL
Sequence: MNIDIVISADHIDEKRLINKTVIIIDILRATSVITTAINNGCKKVIPVLTVEEAKDIAKNSKEDIILGGERNALKIDGFNFSNSPLEYTKKYVEGKTVVLSTTNGTRAINNSFNAKTILISALINSKATAKAIDKLNEELIIINSGTNGQFSIDDFICSGYLIDCLYNIRKDLELSDIAKTAHYIYTNNKDIESFVKKATHYSRLKSLNLEKDLEYCFQKDIIDVVPQYKDGYIIKSNI
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: RSMJ_MAGMM
Sequence: MSLLSVMPATTAQQSRAEQVAHHFHWPLVAVEALCPTPLLLWVGPTGLALKSADGKHQHPITAQLQGGSIGLAGPDSWVRGQPLARAVGIKGQHTPTVVDATAGLGGDGWLMARMGCSMHWAERVPLMGLLLQEGLEQAHQDAQRAEVARRVTLHQADAIQLLQNMQEPPQVVYLDPMFPHEGKGSLPRKAMVQLRQLAGEDQDLPQLFELAMATAEQRVVLKRPLKAPLLTRAKPNFQLKGRSTRFDVYATG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_LACE2
Sequence: MYAIIATGGKQYTVSEGDTIRVEKLAVNAGDTVTFDQVLFVNNGEAKVGEPTVAGATVTASVVGEGRDKKVIVYKYKRKTGYHKKNGHRQAYTEVKIEKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: KEFG_SALTI
Sequence: MSQPAKVLLLYAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTLASHAKAYGEWLANPVSAGGY
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ZBT38_RAT
Sequence: MTVMSLSRDLKDDFHSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLYFKNIFWSHTICISSHVLELDDLKAEVFTEILNYIYSSTVVVRRQETVTDLAAAGKRLGISFLEDLSDRNFSNSPGPYVVCITEKGVVKEEKNEKRHEEPAVTNGPRITNAFSIIETENSNSMFSPLDLRASFKKVSDAMRTTSLCQERASVCPEAEPVRTLAEHSYAVSSITEAYRSQPLREHDSSSSSGKTGKENGEALTTKAKPCRKPKTQTQDSDSTTENMPLPLVTCPEVNQERSPQPAPILSHSEPPSSEGDVHFPREDENQPSETPGPPAAEVPPLVYNCSCCSKSFDSSTLLGAHMQLHKPTQDPFVCKYCNKQFTTLNRLDRHEQICMRSSHMPMPGGNQPFLENYPTIGQDGGSFTSPDSLVPESRIGELSSAGSALSDADHMVKFVNGQMLYSCVVCKRSYVTLSSLRRHANVHSWRRTYPCHYCNKVFALAEYRTRHEIWHTGERRYQCIFCLETFMTYYILKNHQKSFHAIDHRLSISKKTANGGLKPTVYPYKLYRLLPMRCKRAPYKSYRNSSYESAQGNRQRNESPPDTFVIPNLPSSEMPTLNFQDGRNSLTSSPAIPVETPSWQGTPTSAKVKNAEGLKWRKQALKTDLVDSAEVSISSIGNSVSTTLQAEPVCVSSGEHSASVISYSGLVPSVIVHSSQFSSVIKHSNAIACLANSNHQSPSQPVASPSLIKDSKPEADKASKLASRPKNSKEKKKTVPCNRGEITEEAKYVADLGGSSGKTTNVVEETSKIETYIAKPALPGTSTNSNVAPLCQITVKIGNEAIVKRHILGSKLFYKRGRKPKYQMQEETLPRESDPETRGDSPLGLCQADCVEMSEAFDEVSDQDSTDKPWRPYYNYKPKKKSKQLRKIRKVKWRKERGSRSPVGRRRYPAELDRAEMGRRRYPAELDRCAEVKLPPDKASEEEENKEMPKLQCELCDGDKAAGAGAEGKPHQHLTLKPYICELCAKQFQSSSTLKMHMRCHTGEKPYQCKTCGRRFSVQGNLQKHERIHLGVKEFICQYCNKAFTLNETLKIHERIHTGEKRYHCQFCFQGFLYLSTKRNHERRHVREHDGKGFACFQCPKICKTAAALRMHQKKHLFKTLTKQEETDDLCHENSDLLESQPCTDSEDSDQKDDIKKPLLKMSFE
What is the function of this protein?
Transcriptional regulator with bimodal DNA-binding specificity.  Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements (5'-CACGTG-3').  Can also bind specifically to a single methyl-CpG pair.  Represses transcription in a methyl-CpG-dependent manner.  Plays an important role in regulating DNA-replication and common fragile sites (CFS) stability in a RBBP6- and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication (By similarity).  Acts as a transcriptional activator.  May be involved in the differentiation and/or survival of late postmitotic neurons (PubMed:15713629).
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 38, Zinc finger protein expressed in neurons, Zenon.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to chromocenters.
Protein: AB20B_ARATH
Sequence: MMISRGLFGWSPPHMQPLTPVSEVSEPPESPSPYLDPGAESGGGTGTAAALAEADEEMDDQDELEPPPAAVPFSQLFACADRFDWVLMIVGSVAAAAHGTALIVYLHYFAKIVDVLAFSNDSSQQRSEHQFDRLVQLSLTIVYIAGGVFISGWIEVSCWILTGERQTAVIRSKYVQVLLNQDMSFFDTYGNNGDIVSQVLSDVLLIQSALSEKVGNYIHNMATFISGLVIGFVNCWEIALITLATGPFIVAAGGISNIFLHRLAENIQDAYAEAAGIAEQAISYIRTLYAFTNETLAKYSYATSLQATLRYGILISLVQGLGLGFTYGLAICSCALQLWIGRFFVHNGRANGGEIIAALFAVILSGLGLNQAATNFYSFDQGRIAAYRLFEMITRSSSVANQEGAVLASVQGNIEFRNVYFSYLSRPEIPILSGFYLTVPAKKAVALVGRNGSGKSSIIPLMERFYDPTLGEVLLDGENIKNLKLEWLRSQIGLVTQEPALLSLSIRENIAYGRDATLDQIEEAAKNAHAHTFISSLEKGYETQVGRAGLAMTEEQKIKLSIARAVLLNPTILLLDEVTGGLDFEAERIVQEALDLLMLGRSTIIIARRLSLIKNADYIAVMEEGQLVEMGTHDELINLGGLYAELLKCEEATKLPRRMPVRNYKESAVFEVERDSSAGCGVQEPSSPKMIKSPSLQRGSGVFRPQELCFDTEESPKAHSPASEKTGEDGMSLDCADKEPTIKRQDSFEMRLPHLPKVDVQCPQQKSNGSEPESPVSPLLTSDPKNERSHSQTFSRPLSSPDDTKANGKASKDAQHKESPSFWRLAQLSFPEWLYAVLGSLGAAIFGSFNPLLAYVIALVVTEYYKSKGGHLREEVDKWCLIIACMGIVTVVANFLQHFYFGIMGEKMTERVRRMMFSAMLRNEVGWFDDEENSPDTLSMRLANDATFVRAAFSNRLSIFIQDSFAVIVALLIGLLLGWRLALVALATLPILTLSAIAQKLWLAGFSKGIQEMHRKASLVLEDAVRNIYTVVAFCAGNKVMELYRMQLQRILRQSYLHGMAIGFAFGFSQFLLFACNALLLWCTALSVNRGYMKLSTAITEYMVFSFATFALVEPFGLAPYILKRRKSLISVFEIVDRVPTIEPDDNSALKPPNVYGSIELKNVDFCYPTRPEILVLSNFSLKISGGQTVAVVGVSGSGKSTIISLVERYYDPVAGQVLLDGRDLKLYNLRWLRSHMGLVQQEPIIFSTTIRENIIYARHNASEAEMKEAARIANAHHFISSLPHGYDTHIGMRGVELTPGQKQRIAIARVVLKNAPIILIDEASSSIESESSRVVQEALDTLIMGNKTTILIAHRAAMMRHVDNIVVLNGGRIVEEGTHDSLAAKNGLYVRLMQPHFGKGLRQHRLI
What are the official names of this protein?
ABC transporter B family member 20, ABC transporter ABCB.20, AtABCB20, Multidrug resistance protein 14, P-glycoprotein 20.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TNNT3_MOUSE
Sequence: MSDEETEQVEEQYEEEEEAQEEEVQEEAPEPEEVQEDAVAEEEREEDEEEEKPRPKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELIALKERIEKRRAERAEQQRIRAEKEREPQNRLAEEKARREEEDAKRRAEDDMKKKKALSSMGANYSSYLAKADQKRGKKQTAREMKKKILAERRKPLNIDHLSDDKLRDKAKELWDTLYQLETDKFEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGATAKGKVGGRWK
What is the function of this protein?
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin T, fast skeletal muscle, TnTf, Fast skeletal muscle troponin T, fTnT.
What is the protein family that this protein belongs to?
Belongs to the troponin T family.
Protein: CAPSD_HEVPA
Sequence: MRPRPILLLLLMFLPMLPAPPPGQPSGRRRGRRSGGSGGGFWGDRVDSQPFAIPYIHPTNPFAPDVTAAAGAGPRVRQPARPLGSAWRDQAQRPAAASRRRPTTAGAAPLTAVAPAHDTPPVPDVDSRGAILRRQYNLSTSPLTSSVATGTNLVLYAAPLSPLLPLQDGTNTHIMATEASNYAQYRVARATIRYRPLVPNAVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASELVIPSERLHYRNQGWRSVETSGVAEEEATSGLVMLCIHGSPVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRVSRYSSTARHRLRRGADGTAELTTTAATRFMKDLYFTSTNGVGEIGRGIALTLFNLADTLLGGLPTELISSAGGQLFYSRPVVSANGEPTVKLYTSVENAQQDKGIAIPHDIDLGESRVVIQDYDNQHEQDRPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQSTYGSSTGPVYVSDSVTLVNVATGAQAVARSLDWTKVTLDGRPLSTIQQYSKTFFVLPLRGKLSFWEAGTTKAGYPYNYNTTASDQLLVENAAGHRVAISTYTTSLGAGPVSISAVAVLAPHSVLALLEDTMDYPARAHTFDDFCPECRPLGLQGCAFQSTVAELQRLKMKVGKTREL
What is the function of this protein?
Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter.  The capsid is composed of 60 copies linked to each other (By similarity).  Binds to the 5' end of the genomic RNA to mediate genome encapsidation (By similarity).  Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry (By similarity).  Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes (By similarity).  Inhibits IFN production by blocking host IRF3 phosphorylation (PubMed:31717991).  The nuclear form probably modulates host gene expression (PubMed:36007070).
What are the official names of this protein?
Pro-secreted protein ORF2, Protein ORF2, pORF2.
What is the protein family that this protein belongs to?
Belongs to the hepevirus capsid protein family.
What are the subcellular locations of this protein?
[Isoform Secreted protein ORF2]: Secreted. SUBCELLULAR LOCATION: [Isoform Capsid protein ORF2]: Virion. Host cytoplasm. Host endoplasmic reticulum. Host Golgi apparatus. Host cell surface.
Protein: NADA_SHIBS
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNDLQAIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_MANSM
Sequence: MATINQLVRKPRVKKVVKSNVPALQACPQKRGVCTRVYTTTPKKPNSALRKVCRIRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVKDRKQGRSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CDCA2_BOVIN
Sequence: MDTCSQESEPLQTKESPINNAGKTPLVLGNGKLVTPHKQAAEMTPNCYTSETFKSPLNFSTVTVEQLGISPESFVNNSSGKSSPYLKKSRRRSTVGLRGLPETNHLIRFVAEQRSLKNASLTQTSPFQGSPALYRNVYSLREQMSAFHLAFNSIKENEKMTDCPEFSEAEGVFKTRGSTKKESLGECQLSEFSAQSSSKRRRLSSPSSSDVNLTDAVDLQACGVNMAACPSTDMKCAVETCAGLSQKSSASGLNLQCGCLMNESPLLSELTEASSGIQDAASVEERGSNDAVSVDKCTEVSTDTAPEVRSLVTPLCQKDLPSSKTFVLRSVLKKPAVKLCVESLQEHLDNLYNDETCPSLTSSLANSCKEQTAALPNTKKRKRVTFGEDLSPEVLDESLPANTPLRKGQTPVRKKDLSSLSPPLLEQSPVPEWLPQPNFDDKEENLENIEPLQVSFAVLSSLNMSSIAETLSGTDTSASSSNHENIAPFRVGRATRTSDRRSKLISFSQESVCNLLNAEAQPCKEKKTNRRKSQESKHADKVLPRKNRVLKGCKKKKGKGKRKGVQKSLYGERDLASKKPLLSPIPELPEVSETPLVGSLVRRTYPDDFNSNGKFEEMMLPKRENLLSQDPEDWQVIQGFNKDNASESCSSDMKSSSSFSNATFEQDANINSIEMDENENIPKAITLESENERKTGTECENSHISCTLVTVTPVVSDNPKPDFPLQSQELSAAGQNVENLFQIVKISEDMNIKCEKQSGFSVIPEDKLQTEHLIPDSQKECDCSEDVLTDQRKVSKSQGEDLGRNSAASCSGVSDRERKYRGHSVGGSDGPGLHLERTNNLQTSYSMSSLVEISLENSELCKDLSDSIEQSLQRTKSETKVRRSLRLQKSLEREGGLVWVSPPPPPASCTSQRTKRRTVGTLDSRGFEPVSSRQDPCTLPSTSSEENGEGFTAAPDASLPGKRRRRSFCTSTLANPKSTTQSRGCKRRSFLGQKRENTLQETSRESDLSEN
What is the function of this protein?
Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase.  Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase.  At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates (By similarity).
What are the official names of this protein?
Cell division cycle-associated protein 2.
What are the subcellular locations of this protein?
Nucleus. Note=Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin (By similarity).
Protein: IF3_STAAM
Sequence: MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_PSEAE
Sequence: MTTSDLPAFWTVIPAAGVGSRMRADRPKQYLDLAGRTVIERTLDCFLEHPMLRGLVVCLAEDDPYWPGLDCAASRHVQRAAGGAERAGSVLNGLLRLLELGAQADDWVLVHDAARPNLTRGDLDRLLEELAEDPVGGLLAVPARDTLKRSDRDGRVSETIDRSVVWLAYTPQMFRLGALHRALADALVAGVAITDEASAMEWAGYAPKLVEGRADNLKITTPEDLLRLQRSFPH
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.