PharMolix/UniProtQA huggingface dataset:
Protein: ORYZ_NEOFI
Sequence: MLSIKRTLLLLGAVLPAVFGAPVQETRRAAQKIPGKYIVTFKPGTDAATIESHTLWATDLHKRNLERRDATSGEPPIGIEKNYKIKDFAAYAGSFDDTTIEEIRKSADVAHVEEDQIWYIDALTTQKGAPWGLGSISHKGQASTDYIYDTSAGAGTYAYVVDTGINVNHVEFEGRASLAYNAAGGSHVDSVGHGTHVAGTIGGKTYGVAKKTNLLSVKVFQGESSSTSIILDGFNWAANDIVSKGRTRKAAINMSLGGGYSYAFNNAVENAFDEGVLSVVAAGNENTDASNTSPASAPNALTVAAINRSNARASFSNYGSVVDIFAPGQDILSAWIGSNTATNTISGTSMATPHIVGLSVYLMGLESLSGPAAVTSRIKQLATNGVVTNAQGSPNKLAYNGNA
What is the function of this protein?
Secreted alkaline protease that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Alkaline protease 1, ALP, Aspergillopeptidase B, Aspergillus proteinase B, Elastase, Elastinolytic serine proteinase, Oryzin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KEX1A_KLULA
Sequence: MILSSQLMLALIAVSGYGKAMQVPKKDHENRQYFAIESYDDVGNLLAEHSDWSFEHDVRGLANHYVFSKPLQSLGKRDAIDTGYSENIIDFHDLPPVQLHKRLPIGDSSMEQIQNARILFNISDPLFDQQWHLINPNYPGNDVNVTGLWKENITGYGVVAALVDDGLDYENEDLKDNFCVEGSWDFNDNNPLPKPRLKDDYHGTRCAGEIAAFRNDICGVGVAYNSKVSGIRILSGQITAEDEAASLIYGLDVNDIYSCSWGPSDDGKTMQAPDTLVKKAIIKGVTEGRDAKGALYVFASGNGGMFGDSCNFDGYTNSIFSITVGAIDWKGLHPPYSESCSAVMVVTYSSGSGNYIKTTDLDEKCSNTHGGTSAAAPLAAGIYTLVLEANPNLTWRDVQYLSILSSEEINPHDGKWQDTAMGKRYSHTYGFGKLDAYNIVHMAKSWINVNPQGWLYLPTIVEKQSISNSDEVIESTVSVSAEEFKQNNLKRLEHVTVTVDIDAPYRGHVLVDLISPDGVTSTLATARRLDKNRYGFQNWTFMSVAHWGSSGVGSWKLKVKSTHDNEIVTLKSWRLKMFGETIDAKKAKVISYGNDKEDAEVKSTESKTTTPTAQTSSFTTTSGEETSGANKLPRPEQAAQLYLAIFVIGAIVIIIYYLFFLKSRRIIRRSRAEAYEFDIIDTDSEYDSSINQTAESISGEVNDDNLEDFNFDINEEELSPRESSSNNPFGNESLESFDNSPDHTSNLLGQNSIPNK
What is the function of this protein?
Probably involved in the processing of the precursor of m1-toxin and alpha-factor.
What are the official names of this protein?
Protease KEX1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GPMA_CLOB8
Sequence: MIKLVLVRHGESLWNLENRFTGWTDVDLSENGLKEARRAGKILKKNGFVFDVAYTSVLKRAIRTLWIILYEMDLAWIPVFKSWRLNERHYGALQGLNKAETAKKYGEEQVHKWRRFVNVKPPELTKEDTRYPGNEYKYKDLNEEQIPLTENLADTERRVLEEWRGNIAKDLKEGKRVIISAHGNTLRALVKYLDDIPADNVANLNIPTGIPLVYELDEKLKPITHYYLSDKE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: AT2B3_HUMAN
Sequence: MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEERLRAPPPPSPNQNNNAIDSGIYLTTHVTKSATSSVFSSSPGSPLHSVETSL
What is the function of this protein?
ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals (PubMed:25953895, PubMed:27035656, PubMed:22912398, PubMed:18029012).  Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment (PubMed:25953895, PubMed:27035656).  May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established (By similarity).
What are the official names of this protein?
Plasma membrane calcium-transporting ATPase 3, PMCA3, Plasma membrane calcium ATPase isoform 3, Plasma membrane calcium pump isoform 3.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Presynaptic cell membrane; Multi-pass membrane protein. Note=Localized at parallel fiber terminals.
Protein: HIS6_XYLF2
Sequence: MLSRRIIPCLDVRDGRVVKGVKFRDHVDMGDIVELALRYRDHGADELVFYDIGASPQGRSVDYRWVERVARLIDIPFCVAGGIGEVETARAVLHAGADKISINSPALRQPALISALAEAFGVQCVVVGIDSIREADGQWRVRCNTGDPDKTQALPLRTLDWIVEAQRLGAGEIVLNCMDSDGVRCGYDIAQLSQARALCQVPLVASGGAGDMQHFADVFHKADVDGALAASVFHSGAISIPGLKQFLREQQIEVRDV
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA1_BRADU
Sequence: MHEMAICMGIIQIVEEKVRERSSSRVRSVCLELGTLSHAAPEAIRFCFAVAAMRTVAEGAALNIVELPGVAWCMSCSKSVEIARRGDCCPCCGSYQLQVTAGEQMRVKALEID
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA 1.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: NINAB_DROME
Sequence: MAAGVFKSFMRDFFAVKYDEQRNDPQAERLDGNGRLYPNCSSDVWLRSCEREIVDPIEGHHSGHIPKWICGSLLRNGPGSWKVGDMTFGHLFDCSALLHRFAIRNGRVTYQNRFVDTETLRKNRSAQRIVVTEFGTAAVPDPCHSIFDRFAAIFRPDSGTDNSMISIYPFGDQYYTFTETPFMHRINPCTLATEARICTTDFVGVVNHTSHPHVLPSGTVYNLGTTMTRSGPAYTILSFPHGEQMFEDAHVVATLPCRWKLHPGYMHTFGLTDHYFVIVEQPLSVSLTEYIKAQLGGQNLSACLKWFEDRPTLFHLIDRVSGKLVQTYESEAFFYLHIINCFERDGHVVVDICSYRNPEMINCMYLEAIANMQTNPNYATLFRGRPLRFVLPLGTIPPASIAKRGLVKSFSLAGLSAPQVSRTMKHSVSQYADITYMPTNGKQATAGEESPKRDAKRGRYEEENLVNLVTMEGSQAEAFQGTNGIQLRPEMLCDWGCETPRIYYERYMGKNYRYFYAISSDVDAVNPGTLIKVDVWNKSCLTWCEENVYPSEPIFVPSPDPKSEDDGVILASMVLGGLNDRYVGLIVLCAKTMTELGRCDFHTNGPVPKCLHGWFAPNAI
What is the function of this protein?
Catalyzes the oxidative cleavage at the 15,15'-double bond of carotenoids and the simultaneous all-trans to 11-cis isomerization of one cleavage product.  Carotenoids like 11-cis retinal can promote visual pigment biogenesis in the dark.  Essential for the biosynthesis of the 3-hydroxyretinal chromophore of rhodopsin from zeaxanthin and for proper photoreceptor development.  Also essential for larval light perception.
What are the official names of this protein?
Carotenoid isomerooxygenase, Beta-carotene 15,15'-monooxygenase and retinoid isomerase, Beta-carotene dioxygenase and retinoid isomerase, Neither inactivation nor afterpotential mutant B.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
Protein: GLB2_PETMA
Sequence: MPIVDTGSVAPLSAAEKTKIRSAWAPVYSNYETSGVDILVKFFTSTPAAQEFFPKFKGLTTADQLKKSADVRWHAERIINAVNDAVVSMDDTEKMSMKLRDLSGKHAKSFQVDPQYFKVLAAVIADTVAAGDAGFEKLMSMICILLRSAY
What are the official names of this protein?
Globin-2, Globin II, Hemoglobin PmII'.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MUTL_BRUA4
Sequence: MPIRHLSETIINQIAAGEVIERPASVIKELVENAIDAGATRIEVVTGGGGKTLLRVTDNGSGIPVDELPLAVSRHCTSKLSDDVHDIRALGFRGEALPSIGSVAKLTLKSRPQDADSGFEVSVSGGHLDGPRPSALNRGTIAEVRDLFFATPARLKFMKTDRAEASAITDVVKRIAIAFPHVRFSLAGTDRTPLELAATGSGAEATLERINQVLGKEFGENALAIDAERDGVRLAGFVGIPSHNRGNALHQFAYVNGRPVRDKQLFGALRGAYADVMARDRHPVAVLFLTLDPAFVDVNVHPAKADVRFRDPGLVRGLIVGAIKQALAQSGIRPATSGADAMLQAFRAEGFQPPSPSFTSRPSSAGYASGSWHPAVSSPRTEWSPQTAHPAHRPLDLGAAPSFQESDQATLATVNVLAADARATRDEAPVELQQKPLGAARAQIHANYIVSQTEDSLVIVDQHAAHERLVYEALKNALHSRPISGQMLLIPEIVDLPEEDAERLATHAETLARFGLGIEQFGPGAIAVRETPAMLGEMNVQQLIRDLSDEIAEHDTSEGLKAMLNHVAATMACHGSVRSGRRLKPEEMNALLREMEATPGSGTCNHGRPTYIELKLTDIERLFGRR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DNAG_CHLMU
Sequence: MYYTEESLETLKHSIDIVSVLGEYVHLKRSGADYKACCPFHDEKTPSFIVYPTRGHYHCYGCGEHGDAINFLMKQQGYSFSEAVLFLAKKFHVDLVIKTKTKESSGQDSKECLRRINKEAERFFQYCLLCLPEGGEALSYLYKRGFSLDTIDRFQIGYAPEQRVFVRAMEERGISVKQLEWAGYLSKDWFLFAQRIMFPIQDSLGYTIGFSSRRFKEGGKGGKYINSPETLLFKKSRVLYGLQFSRKRIAKEKRVILVEGQADCLQMIDFGFNCTLAAQGTSFTETHVKELVKLGVSKAYLLFDGDAAGEKASLRVGDLCQVAGIAVIVCRLPSGQDPDSFLMQRGPEELRELLDRGEDYLSFLVWHKIRSYEQFTPREKARVVEEVIQQVQHWGSPIMIHEYLRQLASLVKVPEAAVLSYLSSIKSATEDKGKKADAKEVCPDPEATAVAYKGGKASKKISPRMILEADVIRCLLFAKPEEEFVPATVRHYLSPEEFHCIEYRSIFVMAMNHYNEKHMLPSMDDMMALVWGTEAMTLLVDRRINTELMRDIVVQAIQKLLDKHWRDRKRNFCHQMGKELDSLQEYVRLSEERIKVSLVS
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: RL10_PSYWF
Sequence: MALTLEQKQKVVAEVSEVAANAYSAVAADYHGLEVAQLTKLRNQAREKGVVLKVVKNTLAKRAFEGTSFECMSDKMVGPLLLAFSTEDLGSAARVIHEFAKEHKALEPKLVSVGGELFGPEEIERVAKLPTRDEALSILMATMKAPVTKLARTMKEVPGKFVRTVAAVKDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SYE_LEPBP
Sequence: MTEVRTRFAPSPSGFLHVGGARTALFNYLYAKAKKGKFLLRIEDTDQDRSTEASFKIILESLKWLGMEWDEGPGVGGPNGPYTQSERIHIYKEYTDKLIQEKKAYRCFCTAEELEGKKKQADAMGIPYIYDGKCSDLSDAEIGSQLEKKIPFTVRFKTPHKIVIVDDMIQGKVKFESKLIGDFIIVKSDGFPSYNYAVVIDDALMKITHVIRGVGHLSNTPRQILIFEAFGFPLPRFAHASEIVGTDGKKLSKRAGATSVLAFRDLGYSSETMRNYMALLGWTSPDGKEYMSDEELCSVFDVERCSKSPATFDVFKKLKEEEKESVDFNKLTILGLAEYLNPKSKLNWMSNKYIRDTKIETLGKALEPFLKDCQIPEAFKSGENPQLLSILDSVRVYLDRLIQAPPYIEEFFLENLSFENDEAKQLVLEGKGKEVVAEFYRIVKESSLTTPDAYKESMAKVGEITGEKGRTLFMPIRAITTGKSHGLELPILFSLLGQEKMVKRMEQLAGILGISLR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_PSET1
Sequence: MIPGEYQLKSGDIELCVGRKSITINVANKGDRPVQVGSHYHFAESNPALSFDREQAYGYRLAIAAGLAIRFEPGQTREVSLIPYSGLRRLYGFRGEVMGPLDNKPKQESV
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_AGRVS
Sequence: MIDPFKRFARPGLFLFDAETAHGLSIAGLKTSLMPKCHLPDDPRLAQTVAGLHFPNPLGMAAGYDKNAEVPDELLGLGFGFAEVGTLTPKPQGGNPKPRIFRLVRDEAVINRLGFNNQGHEAAFARLSARASRPGVVGINIGANKDAEDRIADYVTGIRRFYPLASYFTANISSPNTPGLRDLQAKDSLGHLLDAVLAARADEAAKAGRRVPVFLKIAPDLTEEGMDDIAEVVLARDLDGLIVSNTTLSRDGLTDTRQAGEAGGLSGKPLFEKSTAVLARMRHRVGSALPIIGVGGVSSAQTALEKIKAGADLVQLYSCMVYEGPGLPAAIVKGLSQALDRDGIASIAQLRDSRVDYWRALKV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: V_MUMP1
Sequence: MDQFIKQDETGDLIETGMNVANHFLSAPIQGTNSLSKASIIPGVAPVLIGNPEQKNIQHPTASHQGSKSKGSGSGVRSIIVPPSEASNGGTQIPEPLFAQTGQGGIVTTVYQDPTIQPTGSYRSVELAKIGKERMINRFVEKPRTSTPVTEFKRGGREPCSRPDNPRGGHRREWSLSWVQGEVRVFEWCNPICSPITAAARFHSCKCGNCPAKCDQCERDYGPP
What is the function of this protein?
Plays an essential role in the inhibition of host immune response.  Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway.  Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.  Blocks the type I and II interferon signaling pathways by interacting with host STAT1, STAT2 and STAT3, and mediating their ubiquitination and subsequent proteasomal degradation (By similarity).
What are the official names of this protein?
Non-structural protein V, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: SLAF9_HUMAN
Sequence: MCAFPWLLLLLLLQEGSQRRLWRWCGSEEVVAVLQESISLPLEIPPDEEVENIIWSSHKSLATVVPGKEGHPATIMVTNPHYQGQVSFLDPSYSLHISNLSWEDSGLYQAQVNLRTSQISTMQQYNICVYRWLSEPQITVNFESSGEGACSMSLVCSVEKAGMDMTYSWLSRGDSTYTFHEGPVLSTSWRPGDSALSYTCRANNPISNVSSCPIPDGPFYADPNYASEKPSTAFCLLAKGLLIFLLLVILAMGLWVIRVQKRHKMPRMKKLMRNRMKLRKEAKPGSSPA
What is the function of this protein?
May play a role in the immune response.
What are the official names of this protein?
SLAM family member 9, CD2 family member 10, CD2F-10, CD84 homolog 1, CD84-H1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RIMP_GRABC
Sequence: MSVAQTPLEQRIAGLIAPGLADMGFELVRVAVLGREQPTVQIMADRADGSLIGIDDCEAISHAAGALLDVEDVIQSTWNLEVSSAGIDRPLTRVKDWVRFAGHLAKVEMSIPGPGGRRRFSGTVLGADETAARLRLDDGEEVSLPMDGLKKAKLVLTDALIDATAQDAGVADSPQQPN
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_SALTI
Sequence: MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPDIWAEEIAWLKAQQIAEAMA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: PYRG_STAA3
Sequence: MTKFIFVTGGVVSSLGKGITASSLGRLLKDRGLNVTIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTAGKVYSHVLKKERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFIEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMTQDLKDKIALFCDINKESVIECRDADSLYEIPLQLSQQNMDDIVIKRLQLNAKYETQLDEWKQLLDIVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFAKDIDIRWIDSSEVTDENAAEYLADVDGILVPGGFGFRASEGKISAIKYARENNVPFFGICLGMQLATVEFSRNVLGLEGAHSAELDPATPYPIIDLLPEQKDIEDLGGTLRLGLYPCSIKEGTLAQDVYGKAEIEERHRHRYEFNNDYREQLEANGMVISGTSPDGRLVEMVEIPTNDFFIACQFHPEFLSRPNRPHPIFKSFIEASLKYQQNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ICMF_CUPMC
Sequence: MTDLSDVSRTAAAKPPAVPGRGPANKVRFVTAASLFDGHDASINIMRRILQSQGCEVIHLGHNRSVQEVVTAALQEDVQGIAISSYQGGHVEYFKYMIDLLREHGGEHIQVFGGGGGVIVPDEIRELQAYGVARIYSPEDGQRMGLAGMITDMAQRCDIDLTRYAPTTLDTVVAGDRRALAQLITALENGKADPELVSALHAQAKAAAVPVLGITGTGGAGKSSLTDELIRRFRLDQDDALSIAVISIDPSRRKSGGALLGDRIRMNAINHPNIFMRSLATREAGSEISQALPDVIAACKAARFDLVIVETSGIGQGDAAIVPHVDLSLYVMTPEFGAASQLEKIDMLDFADFVAINKFDRKGAQDAWRDVAKQVQRNREQWHSRAEDMPVYGTQASRFNDDGVTMLYQGLVGALGARGMSLKPGTLPNLEGRISTGQNVIVPPARSRYLAELADTVRAYHRRVVAQSKLARERQQLRAAHDMLQGAGHESAALETLASERDVSLGAVERKLLAMWPQMQQAYSGDEYVVKIRDKEIRTGLISTTLSGTKIRKVVLPRFEDEGEILKWLMRENVPGSFPYTAGVFAFKREGEDPTRMFAGEGDAFRTNRRFKLVSEGMEAKRLSTAFDSVTLYGEDPHERPDIYGKVGNSGVSIATLEDMKVLYDGFDLTNPSTSVSMTINGPAPTILAMFMNTAIDQQIDRFRADNGRDPTADEEAKIRAWVLQNVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQEYFVHHQVRNFYSVSISGYHIAEAGANPISQLAFTLANGFTYVEAYLARGMHIDDFAPNLSFFFSNGMDPEYSVLGRVARRIWAVTMRDKYGANDRSQKLKYHIQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAYDEAITTPTAESVRRALAIQLIINREWGVAKCENPNQGSFLIEELTDLVEEAVLQEFERIAERGGVLGAMETGYQRGKIQEESLYYEQLKHDGTLPIIGVNTFRNPNGDPTPQTLELARSSEDEKQSQLHRLTEFHGAHQADAEAMLARLRQAVIDNRNVFAVLMDAVRVCSLGQITHALFEVGGQYRRNM
What is the function of this protein?
Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, and to a much lesser extent, of pivalyl-CoA and isovaleryl-CoA, using radical chemistry (PubMed:22167181).  Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly (PubMed:22167181, PubMed:25675500).  The G-domain of IcmF has also a role in its cofactor repair (PubMed:28130442).  Does not display ATPase activity.
What are the official names of this protein?
Fused isobutyryl-CoA mutase.
What is the protein family that this protein belongs to?
Belongs to the IcmF family.
Protein: YBIX_ECO81
Sequence: MMYHIPGVLSPQDVARFREHLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSALYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPESYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: NORV_ALISL
Sequence: MTIHIKNNVNWVGQRDWEVSDFHGTEFKMTKGTSYNSYLIQEEKTILIDTVDHRFSHQFIQNLEMEIDLTSIDYIVINHAEEDHAGALAALMEKIPGTPIYCTENAIDSIVGHHHHPEWNFKPIKTGDALDIGNGKQLVFVEAPMLHWPDSMMTYLTGDAILFSNDAFGQHYCDERLFNDEVDQTELMDQCLRYYANILTPFSALVTAKIKEVLSFNLPVDMIATSHGCVWRDNPTQIIHQYLEWADNYQEDRITLFYDSMSNNTRMMADAIAQGIHDVDPGVAVKVFNVSRQDKNDILTSVFRSKGILVGSSTMNNVMMPKIAGMLEEITGLRFRAKKAGAFGSYGWNGGAVDRIHSRLTDAGFETAVGLKAKWRPDGKAMQLCREHGQFIAKQWALKPVTTTFQTINVEKKTIPASIAEPVIMVDPSVSSTVESEISVIASNDDKQCMLCTVCNWVYDPEIGEPNQGVEPNTAWIDVPDYFLCPECNLGKDVFVEVK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCAFD_BPPHS
Sequence: MSQVTEQSVRFQTALASIKLIQASAVLDLTEDDFDFLTSNKVWIATDRSRARRCVEACVYGTLDFVGYPRFPAPVEFIAAVIAYYVHPVNIQTACLIMEGAEFTENIINGVERPVKAAELFAFTLRVRAGNTDVLTDAEENVRQKLRAEGVM
What is the function of this protein?
Assembles the procapsid by joining twelve 12S pre-assembly complex into a T=1 icosahedral particle, called 108S procapsid.  Ten proteins D bind each 12S complex, which are formed by three pentamers of F, G, B protein and a H protein.  The scaffolding protein is released from the provirion after genome packaging to form the mature virion.
What are the official names of this protein?
External scaffolding protein D, Scaffolding protein D, GPD.
What is the protein family that this protein belongs to?
Belongs to the microvirus D protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: DF187_ARATH
Sequence: MKNSSIMFVLIVVFLISSSENQKMVGEAKQCKTGWACFGEDACKEKCMAKYKGVGTVTYFPFPPETIIIYCECLYDC
What are the official names of this protein?
Putative defensin-like protein 187, Putative low-molecular-weight cysteine-rich protein 42, Protein LCR42.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURA_CLOPE
Sequence: MSAFVVLGAQWGDEGKGKMTDYLAEEAEVVVRFQGGNNAGHTVEVEDKQYKLHLIPSGILHDEKLNVIGNGVVVDPKALFTEIDYLEGLGVKVTPEKLIVSDRAHLIMPYHITLDKLKEKARGKNDIGTTCKGIGPCYTDKYERSGIRVCDLMHKDSFAEKLRINIEMKNGYIKLLGGEELNFDEIYNEYMAFAERLRPYVKDTSVEIYNAIQADKNVLFEGAQGMLLDIDYGTYPYVTSSNTTSCGVASGAGIGPNMVTNAVGIAKAYTTRVGKGPFPTELENETGDWIREKGHEYGVTTGRSRRCGWLDLVILKTTTRVCGLTSLVVTKIDTLAGLDKIQMCVGYELDGKVIDYFPASLEDLARCKPVYEEFEGWGEEVADARSYEELPENAKTYLRRIEEFTGTKVSIVGVGPKRNQTIRVREEL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_SALTI
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFARHHGGEFVLRIEDTDLERSTPEAIEAIMDGMNWLNLEWDEGPYFQTKRFDRYNAVIDEMLEAGTAYKCYCSKERLEQLREDQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQDGSVIFDDQIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALNAPVPMYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSSGDQEIFTREEMIKLFSLGAVSKSASAFNTDKLLWLNHHYINTLAPEYVATHLQWHIEQENIDTRNGPQLAELVKLLGERCKTLKEMAQSCRYFYEDFSEFDADAAKKHLRPVARQPLEVVRDKLSAITDWSAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGKTRSIERINKALGFIAERESQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.