PharMolix/UniProtQA huggingface dataset:
Protein: ACD11_ARATH
Sequence: MADSEADKPLRKISAAFKKLAIIVNSPNPEVPVTQFSHACSLVSPLFGCLGIAFKFAEMDYVAKVDDLVRASSSISTLVVMMDKDIEADCVRKAGSHTRNLLRVKRGLDMVKVLFEQIIASEGDNSLKDPATKSYAQVFAPHHGWAIRKAVSLGMYALPTRAHLLNMLKEDEAAAKIHMQSYVNSSAPLITYLDNLFLSKQLGIDW
What is the function of this protein?
Exhibits selective intermembrane transfer of ceramide-1-phosphate (C1P) and phytoceramide-1-phosphate (PubMed:24412362, PubMed:28011644).  Does not transport ceramide (Cer) or GalCer, suggesting a requirement for phosphate in the headgroup for functionality (PubMed:24412362).  Transports in vitro sphingosine, but not glycosphingolipids (PubMed:11850411).  Has also some in vitro activity with sphingomyelin, a lipid not detected in plant tissues (PubMed:18657186).  The transport function may be not directly involved in regulating cell death.  Rather, perturbations in the function of ACD11 or related components could be monitored by R-proteins, which then mediate defense and programmed cell death (PCD), as proposed in the guard hypothesis (Probable).  C1P transfer is stimulated by phosphatidylserine in C1P source vesicles (PubMed:28011644).  Regulates autophagy, inflammasome mediated IL1B and IL18 processing, and pyroptosis, but not apoptosis (PubMed:28011644).
What are the official names of this protein?
Accelerated cell death 11, Ceramide-1-phosphate transfer protein ACD11, Glycolipid transfer protein domain-containing protein ACD11.
What is the protein family that this protein belongs to?
Belongs to the GLTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_CLOBH
Sequence: MSAFIVLGAQWGDEGKGKMTDYLAENADVVVRFQGGNNAGHTVVVGEKEYKLHLIPSGILYNDKLNVIGNGVVLDPKALFEEINYLESLGVEITPDRLIISDRAHVIMPYHRILDGIKERARGNKDIGTTGKGIGPSYTDKMERSGIRVCDLIHKEVFEENLKETLEVKNKIITEIFGGRALDYNEIYNEYLGYAEKLRPFVKDISVIVNKKIKDGKEVLFEGAQGTLLDIDYGTYPYVTSSSTIAGGVCIGAGVGPTAITNAVGIAKAYTTRVGKGPFPTELLDSTGDWVREKGHEFGVTTGRARRCGWLDLVILKTSARISGLTSFAVTKIDTLAGLDTLKVCTGYRLNGEIIDYVPASLEDLAKCEPIYEEFEGWDDSIANARCYEDLPENAIKYLKKIEDFTETKVSIVSVGPKRDQTMMISEI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL1_YERPB
Sequence: MSLKQHTQTIFRQQFDRESDITIKAPGRVNLIGEHTDYNDGFVLPCAINYETVISCGKRGDRQIRVIAADYENQQDIFSLDAPIVPHPEYRWADYVRGVVKHLQMRNADFGGADLVICGNVPQGAGLSSSASLEVAVGQALQSLYQLPLSGVELALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRTLETRAVPMPENMAVVIINSNIQRGLVDSEYNTRRQQCEAAARFFGVKALRDVEPSLFFSIQDELDPVVAKRARHVISENARTLAAADALAAGNLKLMGQLMQESHISMRDDFEITVPPIDRLVEIVKSVIGDQGGVRMTGGGFGGCIVALMPLELVEQVRTTVAQEYPAHSGGKKETFYVCQASQGAGLC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASPA_SHIFL
Sequence: MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSLIKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHPAYKAKRYTDESEQ
What are the official names of this protein?
Aspartate ammonia-lyase, Aspartase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.
Protein: TTHY_CROPO
Sequence: MAFHSMLLVFLAGLVFLTEAAPLVSHGSIDSKCPLMVKVLDAVRGSPAANVAIKVFKKTSDGDWQEFAAGKTTEFGEVHELTSDEKFVEGIYRVEFDTSSYWKALGLSPFHEYADVVFTANDSGHRHYTIAALLSPFSYSTTAVVSDPQE
What is the function of this protein?
Thyroid hormone-binding protein, with a much higher binding affinity for triiodothyronine (T3) than for thyroxine (T4).  Probably transports triiodothyronine from the bloodstream to the brain.
What are the official names of this protein?
Transthyretin, crocTTR, Prealbumin.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TEG3_EHV1V
Sequence: MSFSARSRRQRLQLEEAYQREMIFKMHTLDLVREGVNKRSPAFVRAFTSAKEASLDLDRYMQAHSRVGRVEQNARALAQRVEAQAAVGEILDRHRRFLHPDFIDNFDSREDSIVEREERLGDVLSDINCDGGGGEVGDPQEWLGHEDEALLMRWMLEEAPRVSTRIAADPHSPRSTCPAPRKAPEDARCGARKPGEVNNYTPSAQPRSQETTVDHLASPDEGTRLGDRTRDLEHHSTAPMRTHPNVLASERRRLGVVHQREKSSESQESATRSKAIVGQEDQKWLGGIPPLSDEELQVDMGIPTMNGPIYPDYHRTA
What is the function of this protein?
Contributes to the nuclear transport of the viral transcriptional activator VP16 during the early phase of infection.  Therefore, participates indirectly in the regulation of the immediate-early gene expression.  Additionally, seems to be important for efficient nuclear targeting of capsids (By similarity).
What are the official names of this protein?
Tegument protein UL14 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL14 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: GLYA_BRUSI
Sequence: MSQANAATKASSDVFFNASLEDIDPEIFGAIRNELGRQRHEIGLIASENIVSRAVLEAQGSILTNKYAEGYPGKRYYGGGQYVDVVEELAIERAKKLFGAEFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLNSGGHLTHGSPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAGGTAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRGPRGGMILTNDADIAKKINSAVFPGLQGGPLMHVIAGKAVAFAEALKPEFKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEIGSLIAEVLDGLKVANSDEGNAAVEQAVKEKVIALTGRFPMYGYQG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUTB_BACHK
Sequence: MSMKISEKKFNDRVGDGIQDSFMRGAVSSAQTRLYTNRLKAADELGNWEEWRELGEEIRQHTLENLDYYLMQLSENVSKRGGHVYFAKTKEEAAKYIQDVAKKKQAKKVVKSKSMVTEEISMNHALEEIGCEVLESDLGEYILQVDNDPPSHIIAPALHKNRTQIRDVFKEKLGYENSDDPYEMTKFVRKQLREKFMDAEIGVTGCNFAVANTGSLCLVTNEGNADLVMSIPKTQIAVMGMERMVPTMEELDVLVGLLCRSAVGQKLTSYVTVAGPIQEEEVDGPEEFHLVVVDNGRSQILGSEFRQVLQCIRCAACVNVCPVYRHVGGHSYGSIYSGPIGAVLTPLLGGYDDYKELPYASSLCGACTEACPVKIPLHDLLLKHRQVIVEQEGRAPLAEKLAMKMFSMGASSAALYKMGSKMAPAAMSPFTSGNRVSKGVGPLKNWTDIREFPAPSKERFRDWYKDHKKGGDK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: TIG_SYNJB
Sequence: MQVTQEKRPGSRVGLKIVVEADRVKRSYEKTLRQLEQNIQIPGFRKGKAPRNLVVRQVGRERILASAVDDLINEAIQQAFKEAQLTPISRFELDDEVGQLLAQFNPEADFSFSGYVEVYPEARVGQYKGLTVTATRVDVKPEQIDQLIDRWRDQRATLLPVEDRPAQLGDVVVIDFAARDAEGNPLDEMTTQDFQLELKEDNFIPGFVAGIVGMQLDETKEIAATFPDDYFRKELAGKTVTFIVCLREIKAKELPELDDAFVQEISSFQTVAELREHLQKRLEQDALRQSEENLETAILNAILETTEVDLPETLIEQETTQLLAQSLQALRQEGIKPGELRKFLSELPPETLNQLKERHRPEAIDRLRRTLALSAIVRQEQIAVGSTELDVEVEEVMAAYAQQGQKLDRERVRQAVYESLLTNKVMAWLKSQTTVNWVDSEGNPTQAPTSLAGSEEKVEVPEAEFEADEPEAEVSGIPEAVESSSETATGAETDGEAAAAEAEPATEKAVEASPAETVSASAAEATLPVEEKAAETATEIPAAEKPKPSKKDKKGK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ISPF_ECO27
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAAQGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYALGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: CLVS1_HUMAN
Sequence: MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
What is the function of this protein?
Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity).  Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).
What are the official names of this protein?
Clavesin-1, Cellular retinaldehyde-binding protein-like, Retinaldehyde-binding protein 1-like 1, clathrin vesicle-associated Sec14 protein 1.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Early endosome membrane; Peripheral membrane protein.
Protein: PRF1_SOLLC
Sequence: MHVLIACPYCPYPPSTPKHPKLPPKVKPPSTQPPHVKPPSTPKHPKDPPHVKPPSTPKQPPYVKPPTTPKHPPHVKPPSTPKHPKHPPQKPCPPPSHHGPKPPIVKPPHVPRPPIVHPPPIVSPPSTPKPPKTPPFTPKPPSPIPPIVSPPIVYPPITPTPPIVHPPVTPKPPSPTPPIVSPPIVYPPITPTPPVVSPPIIPTPPIVSPPFVPNPPVVIPPPYVPSPPVVTPPIVPTPPTPCPPPPPPPAIIPSPPAQPTCPIDALKLGACVDVLGGLIHIGIGGSAKQTCCPLLGGLVDLDAAICLCTTIRLKLLNINIILPIALQVLIDDCGKYPPKDFKCPST
What are the official names of this protein?
36.4 kDa proline-rich protein.
Protein: MURD_RHOJR
Sequence: MAEEHGGLDWLRGRSVLVAGAGVSGRATIEPLRDLGALVTVTDANVDALAECARLGAATVPIDDLLAERDRVAEFALVVTSPGFRPDAPLLSLAAGDGVPIWGDIEFSWHVDRAGLYGPPRRWLVVTGTNGKTTTTSMLQSILEAAELPSLACGNIGIPVLDALRQTEPRAEALAVELSSFQLHWAPSVRPTAGAILNIAEDHLDWHGGMQPYIDAKARALTGEVAVLGLDDEVASSLFSSSPAVRTVGFRLGVPAPGELGVEDGYLVDRAFADGERLAPAEGITPPGPAGLMDALAAAALARAIGVPPDAVAAGLAAHVVGPHRAALVAEVGGVTFVDDSKATNPHAARPSILAHERVVWIAGGLLKGARVDDLVREVASRLAGAVLLGRDAMQIAESLARHAPEVPVVTVETGDDAGVSAVPQTATHRVVLPADTDSDAVMGVVVREAAALATAGDSVVLAPAAASLDMFASYGHRGDSFTDAVGRLDASDISRTLR
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSK21_BOVIN
Sequence: MSGPVPSRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSANMMSGISSVPTPSPLGPLAGSPVIAAANPLGMPVPAAAGAQQ
What is the function of this protein?
Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.  Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection.  May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response.  During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage.  Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation.  Can also negatively regulate apoptosis.  Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3.  Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8.  Phosphorylates YY1, protecting YY1 from cleavage by CASP7 during apoptosis.  Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV.  Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, ATF4, SRF, MAX, JUN, FOS, MYC and MYB.  Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function.  Mediates sequential phosphorylation of FNIP1, promoting its gradual interaction with Hsp90, leading to activate both kinase and non-kinase client proteins of Hsp90.  Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1.  Acts as an ectokinase that phosphorylates several extracellular proteins.  During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV.  Phosphorylates PML at 'Ser-565' and primes it for ubiquitin-mediated degradation (By similarity).  Plays an important role in the circadian clock function by phosphorylating BMAL1 at 'Ser-90' which is pivotal for its interaction with CLOCK and which controls CLOCK nuclear entry (By similarity).  Phosphorylates FMR1, promoting FMR1-dependent formation of a membraneless compartment (By similarity).
What are the official names of this protein?
Casein kinase II subunit alpha, CK II alpha.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUSG_BUCBP
Sequence: MYKSYKKRWYVLQAFSGFEGRIAQSIREHVKLKKMEKLFGEVMVPSEEVIEIKAGQRKKSEYKFFPGYVLIQMIMNESSWHLVRSIPRVLGFIGGTPDRPLPITDQEVNTIINKLKQVGDKPRPKTLFEPGETVRVNDGPFSDFNGIVEEVDYEKNRLKVSVSIFGRSTPVELDFSQVKKN
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.  In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing.  In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho.  May be required to overcome a kinetic limitation of Rho to function at certain terminators.  Also involved in ribosomal RNA transcriptional antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: RSMA_STRPJ
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDILKVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLAEFAGLADALKGQGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_DRANE
Sequence: MEKFQGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNRNRSIFVENSDYEKKYSSLIVKRLIWRMYEQNRLIIPTTDLHKNPVLGHTNHLYYQMISVLFAVIVEIPFSLSLGFSFEGKQIKKSYNLQSIHSLFPFLEDKLSHFNYVLDVLIPYPIHLEILVQTLRYRVKDASSLHFFRFCLYEYGNWKNFDIKKKCILNPRFFLFLYNSHICEYESIFFFLRKRSSHLRSIAYEVFFERILFYGKIHHFFKVFVNNFPATLGLLKDPFLHYVRYHGKNILATKDTPLLMNKWKFYFLNFWQCYFSVWFPSQKVNINQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNIRIKFDSKIPISSIIGSLAKDKFCNVLGHPISKATWTDSSDSDILNRFVRICRKISHYYSGSSKKKNLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSVLLEEFLTGEDQVLSLIFPRSYYASKRLYRVRIWYLDILYLHDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RIC8A_XENLA
Sequence: MDLGALLDELESGDQELVQKSLAEYNQENSQCFFFNAEQREERKKLGELVISFLNRDLQPSCQIACLETIRILSRDKYALSPFTGRSAIQTLAQYAGLDYSEEMEMPCIPDGESAVEALKGLCNIIYNSVEAQEVAKDLRLVCGLARRLKLYNETRSSHESKFFDLRLLFLLTALSVDMRRQLAQELRGVSLLTDALESTLALKWSDIYEVVTDHLAPPLGKEETERVMEILKALFNITFDISRREVDEEEAALYRHLAAILRHCLLRQSDGEDRTEEFHGHTVNLLVNLPLMCLDVLLTPKVEQGSVEYMGMNMDTVEVLLQFLHRRLDRGHKLREMLTPVLNLLTESSRVHRETRKFLRAKVLPPLRDVKNRPEVGNTLRNKLVRLMTHVDTDVKHCAAEFLFVLCKENVSRFVKYTGYGNAAGLLAARGLLAGGRGEGCYSEDDDTDTEEYREAKANINPVTGRVEEKQPNPMDGMTEEQKEYEAMKLVNMFDKLSREQIIQPMGVTSDGRLGPLDEAAQKMLQRQESSDLDSDSD
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.  Involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein (By similarity).
What are the official names of this protein?
Synembryn-A, Protein Ric-8A.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane.
Protein: RK20_AETGR
Sequence: MTRIKRGYIARRRRTKIRLFASSFRGAHSRLTRTMTQQRIRALVSAHRDRGRRKRDFRRLWITRINAVIQEMEVFNSYNRFIHNLYKKQVLLNRKILAQIALLNRSCLYTISNEIIK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMG_SERP5
Sequence: MQKKLDSLLKAAGITLPDRQKQQLLGYVGMLDKWNKAYNLTSVRDPQQMLVRHILDSIVVNPHLQGKRFIDVGTGPGLPGIPLAIVRPDSHFTLLDSLGKRVRFLRQVQHELGLTNVEPVQSRVEEFPAEPPFDGVISRAFASLQDMLSWCHHLPAKGQGRFYALKGVRPDEELTQLPPGIELESVVRLQVPELEGERHLVILKAN
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_LEPIN
Sequence: MSQDKKTPLYETHRTLGAKMIPFGGWDMPVQYSGIIAEHNATREAAGLFDVSHMGEIFITGNPKSILLFLESITCNSVASLSDFQVQYNAILNQNGGLVDDVTIYKFSSEKYMICSNASNYEAVTEHLLEHLPISGVKVDNQSLQWHQIALQGPKANEIFSKFLKRDLDSIQYYRFMLLPYQGEEIIVSRTGYTGEDGFEIYSSIPIGLKLWNELLEFGKPYGLLPCGLGARDTLRIEAKYPLYGHELNDQWTPIESGIGWIVKEKENPYFSSEKILFQKKNGVPSKIVSFALTEAGVPRENFRVLDSQGNEIGKTTSGTFSPSLKKGIGLALIQSEKIKDGEPIQIEIREQPKQAIITMKPFIPGSIRKN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: COBS_DESRM
Sequence: MFSSLRLAISFLTIFPFYNKMADNKELAQSVSYYPLVGFLLGSIAAGVCYAMHSIGLNLAADVLGLVTIITLTGGLHQDGLMDTADGIFSGRELHRKLEIMKDSRVGAMGVIALATVLLLKIAFLFELDLAQKLTAFIMAPMAGRWAMVLAITRYPYARATGGLGACLKQAGKTQLALATLILVAGCLWLFGLPGLALLGIVFFITWLTVEFIVKRLGGMTGDTYGALGEMIETWVIFLILLGQQIRML
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXE_PORG3
Sequence: MNRESFLLLLVLLFALPLHLQASSPCNNMADTTCISDSAKMFPPAIGVYHVKPMKNTLRHSLPLVAASLLTFNVDDNIRELRFTGAGSFHTKIDNVSQLVPLMAQLSMRGFGYKGRSKSWGKMLVSDALGMALMGGMVNAGKYSFGRLRPDGTAANSYPSGHTATAFACATLFHLEYGSRSPWYSVAGYTVASFTGISRIVNNRHWASDVLCGAAVGILVGELGYWISDLIFRDPTGYNYKLTKKQEGTLESMVISLSTGNRYINRQMDFEGKTVERTDAFGMNLKTTFNPSFARWVRIGLQFSVSTEKQKGLTRERPAKVFVAPAISLGLSAGVEWHPWQRASVWAEILPSILFRTDFTNAQDKPDEMSSKLHRRSSFQPAFQVGVAYRVSDHMGIEAHAGYQLGEAVYHLMEETSTWSIIKKRATVPYRGFEFAVGLQFYPFR
What is the function of this protein?
Removes the 1-phosphate group from lipid A species.  Absence of phosphate groups in lipid A renders the bacteria resistant to host-derived cationic antimicrobial peptides (CAMP) and allowing it to camouflage itself from the host innate immune response.
What are the official names of this protein?
Lipid A 1-phosphatase.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y235_HELPH
Sequence: MKKPYRKISDYAIVGGLSALVMVSIVGCKSNADDKPKEQSSLSQSVQKGAFVILEEQKDKSYKVVEEYPSSRTHIVVRDLQGNERVLSDEEIQKLIKEEEAKIDNGTSKLVQPNNGGGSNEGSGFGLGSAILGSAAGAILGSYIGNKLFNNPNYQQNAQRTYKSPQAYQRSQNSFSKSAPSASGMGTASKGQSGFFGSSRPTSSPAVSSGTRGFNA
What are the official names of this protein?
UPF0323 lipoprotein HPAG1_0235.
What is the protein family that this protein belongs to?
Belongs to the UPF0323 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.