PharMolix/UniProtQA huggingface dataset:
Protein: MARF1_BOVIN
Sequence: MEGSGTENPCSTTVGWLQQDNDAKPWLWRFSNCFSRPQQTLPLSPQTKDYMENKKVAVELKDVPSPLHAGSKLFPAVPLPDIHSLQQPKVQLSTVPKVSCCAHCTNDPSTSPVRFGGGSGGGAGSLVPPGALLDSQSTRTITCQVGSGLAFQSAPPLQNASARNTLAGVASDFPSMCLESNLSSCKHLPCCGKLHFQSCRGNVHKLHQFPALQGCPSSAGYFPCSDFTSGAPGHVEEHVSQSELTPHLCTNSLHLNVVPPVCLKGSLYCEDCLSKPARNSIIDAAKVWPNIPPPNTQTAPVTVPLCNGCGTKGMGKETTLLLATSLGKAASKFGSPEVALAGQMLENLPPIGVFWDIENCSVPSGRSATAVVQRIREKFFKGHREAEFICVCDISKENKEVIQELNNCQVTVAHINATAKNAADDKLRQSLRRFANTHTAPATVVLVSTDVNFALELSDLRHRHGFHIILVHKNQASEALLHHANELIRFEEFISDLPPRLPLKMPCHTLLYVYNLPANKDGKSISNRLRRLSDNCGGKVLNITGCSAILRFINRDSAERALKRMENEDVFGNRIVVSFTPKSSELCETKSSNATADKVKSPKKLKNPKLCLIKDISESPSSAKAAPGKGSQANSGSATRNANVKSLQELCRLESKTGTRSSEPQQGHLRLGAPPHRSSSAAAPAPKAPGLAESVYKTNPKKESLGARSVTSSPVEKKEKEETLFQVSYPSAFSKLIASRQVSPLLTAQPWSSRNLSPNLLNRASPLAFNAAHSSVGADGPDPFAHGVDVQISNLDYRLSRKELQQLMQEAFSRHGKVKSVELSPHTDYQLKAVVQMENLQEAIGAVNSLHRYKIGSKKILVSLATGAANKSLSLLSAETMSILQDAPACCLPLFKFTDIYEKKFGHRLNVSDLYKLTDTVAIREQGNGRLVCLLPSSQARQSPLGSSQSHDGSSTNCSPIIFEELEYHEPVCRQHCPNKDFSEHEFDPDSYKIPFVILSLKTFAPQVHSLLQTHEGTVPLLSFPDCYAAEFGELEIVQENRGGGVPLEHLITCVPGVNIATAQNGVKVVKWIHNKPPPPNTDPWLLRSKSPVGNPQLIQFSREVIDLLKNQPSCVIPISNFIPSYHHHFAKQCRVSDYGYSKLIELLEAVPHVLQILGMGSKRLLTLTHRAQVKRFTQDLLKLLKSQASKQVIVKEFAQAYHWCFSKDWDVTEYGVCELIDIISEIPDTTICLSQQDSEAMICIPRRERTQDEIERTKQFSKDVVDLLRHQPHFRMPFNKFIPSYHHHFGRQCKLAYYGFTKLLELFEAIPDILQVLECGEEKILTLTEVERFKALAAQFVKLLRSQKDNCLMMTDLLKEYAKTFGYTFRLQDYDVSSVSALTQKLCHVVKVADMESGKQIQLINRKSLRALTAQLLVLLMSWEGTTHLSVDELKRHYESTHSTPLNPCEYGFMTLTELLKSLPYLVEDQVFTNDKTEECVKLTSLYLFAKNVRSLLHTYHYQQLFLHEFSMAYSKYVGETLQPKTYGFSSVEELLGAIPQVVWIKGHGHKRIVVLKNDMKSRVNSLGPSPASHETQPSAPERILEVPESPPASELRLGVGGDGPHPAEQELLRLTDDSPVDLLCAPVPSCLPSPQLRPDPVVLQAADLIWFEEHPQEPSEIMILNQEEKIEIPVPIRNENLPPDPSSPGVSAAVPAPPSPSSETPESLLSKDPTESPAKKQPKNRVKLAANFSFAPITKL
What is the function of this protein?
Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity.  Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons.  Also required to protect from DNA double-strand breaks (By similarity).
What are the official names of this protein?
Meiosis regulator and mRNA stability factor 1, Limkain-b1, Meiosis arrest female protein 1.
What are the subcellular locations of this protein?
Peroxisome.
Protein: SYE_PSEA7
Sequence: MTTVRTRIAPSPTGDPHVGTAYIALFNLCFARQHGGQFILRIEDTDQLRSTRESEQQIFDALRWLGIEWDEGPDVGGPHGPYRQSERGHIYKKYSDELVEQGHAFTCFCTPERLDAVRAEQMARKETPRYDGHCMHLPKDEVQRRVAAGESHVTRMKVPTEGVCVVPDMLRGNVEIPWDRMDMQVLMKADGLPTYFLANVVDDHLMGITHVLRGEEWLPSAPKLIKLYEYFGWEQPQLCYMPLLRNPDKSKLSKRKNPTSITFYERMGYLPQALLNYLGRMGWSMPDEREKFTLAEMIEHFDLSRVSLGGPIFDLEKLSWLNGQWIREQSVEEFAREVQKWALNPEYLMKIAPHVQGRVENFSQIAPLAGFFFSGGVPLDASLFEHKKLDPTQVRQVLQLVLWKLESLRQWEKERITGCIQAVAEHLQLKLRDVMPLMFPAITGHASSVSVLDAMEILGADLSRYRLRQALELLGGASKKETKEWEKIRDAIPG
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_OLEA2
Sequence: MAHTLAQKILQKHTDQQVGEAGQIVRCRVSMALANDITAPLAIKSFRAMGAGKVFDKDRVALVMDHFTPQKDIDSAIQVKNTREFAAQMGITHYYEGGEAGVEHALLPELGLVGPGDIVVGADSHTCTYGGLGAFATGLGSTDVAGAMALGETWFKVPPSIRVSYRGTMPAHVGAKDLVLQLIGHIGVDGALYKALEFDGPVVDAMSVEGRMTIANMAIEAGGKCGLFPSDDLTLAYTAARGRNDEKLSADQDAVYERSLSFDVSDLAPQIACPHLPENVRPVTEVQGVQIHQAVIGSCTNGRISDLREAAAVLRGRKVHKSVRCIVLPATPGIWKQALREGLIETFMDAGCIVGPATCGPCLGGHMGILADGERAIATTNRNFRGRMGSLESEVYLSNPSVAAASAVAGEIADPRGL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: NADK_CERS5
Sequence: MTPQRIGFVASPAPVAQEALVAMEARYGQCPLPEAEVIVALGGDGFMLQTLHETQSLDIPVYGMNRGTVGFLMNGYAGDGLRERLAEAEEEILNPLVMTAVTEAGEVFHRIAINEVSLLRAGPQAAWLKISVDGKVRMEELVCDGALVCTPAGSTAYNYSAHGPILPIGADVLALTAIAPFRPRRWRGALLPKTATVRFDVIDARKRPVMADADGRSVRDVVSVEVRSEPAIRHRLLFDPGHGLEERLIREQFV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_KINRD
Sequence: MIDDTLLEAEEKMEKAIEVAKGDFGAIRTGRANAAMFHKIMVDYYGAPTPLQQLASFQIPEARSVLITPFDRAAMSEIEKALRNSDLGVNPGNDGNVIRIVLPQLTEERRKDYIKIARTKAEDARVSLRNVRRRAKEELDRIVKDGEAGEDEVGRAEKELEAVTKKHVDAIDELLKNKEAELLAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_TREDE
Sequence: MKCVVFTGGGTGGHIFPGLAVAEALSSSLECRIVWIGSAKGVDRKIVESSELYSASPSVLEFIGIPAGKLRRYFSFQNFIDVFKVAAGFIKSFFILLKLKPVFVFSKGGFVSVPPCAAAKFLKIPVITHECDFSPGLATRINSKFANRILVSYQETAELLPASLRSKVICTGNPVRLSFYSGRPEKGRSFLNIKSNLPVLFVLGGSLGARQLNDLISDSIEYLVKHFVVVHQIGEANMDQGQKIKEGLLKSSPEFAENYKPYPFIKKEMADVLSLSSIVVSRAGANTVWESAAAGKPMILVPLEKGSSRGDQIENAEFFKKKGSAEILLGEDVRPDIFIRLLRDLGFEENISGNERLKNMAQASAALAGEKPALVIADFLKSFFTSKNEDL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HSCA_SHIB3
Sequence: MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQADIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDNAAAHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.  Involved in the maturation of IscU.
What are the official names of this protein?
Chaperone protein HscA, Hsc66.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GSTO1_HUMAN
Sequence: MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHEVININLKNKPEWFFKKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMILELFSKVPSLVGSFIRSQNKEDYAGLKEEFRKEFTKLEEVLTNKKTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDHTPKLKLWMAAMKEDPTVSALLTSEKDWQGFLELYLQNSPEACDYGL
What is the function of this protein?
Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities.  Has S-(phenacyl)glutathione reductase activity.  Has also glutathione S-transferase activity.  Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.
What are the official names of this protein?
Glutathione S-transferase omega-1, GSTO-1, Glutathione S-transferase omega 1-1, GSTO 1-1, Glutathione-dependent dehydroascorbate reductase, Monomethylarsonic acid reductase, MMA(V) reductase, S-(Phenacyl)glutathione reductase, SPG-R.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Omega family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RBD2_KLULA
Sequence: MNIKQFFVPAGKPLSGLAVGLSIFLTALFLVNNLVYPINEHLLLKPDSLFKFDLNRISLYPLAHLSFFHLFFNVISTFSMIVMFEESHGTLYTGVILNLLAVFTAIPYCLIGSLLFPNVEIGGASGWFFSFLGYFAVKESRVRNSVMITSTFSFPTLYFPVALLFVTALLAPGSSLPGHAIGLLLGYFMGLKENWVAKITPPSFVLKKIETWVDPLINLIPFGIKYYREVEVDRSLEYTSVYLGSESRLPLHNTDTPAEPTFQGNGRVLGN
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Rhomboid protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: MINC_ECO55
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGKEKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARLQLVENALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ACPH_ENT38
Sequence: MNFLAHLHLAHLADSSLSGNLLADFVRGNPTQAYPTDVVDGIFMHRRIDVLTDNLPEVKEAKEWFRPETRRVAPITLDVMWDHFLSRHWAQLSPEMPLPEFVRYAHSQVAMILPDSPPRFVNLNEYLWSERWLERYREMDFIQRVLNGMASRRPRLDALRDSWQDLDTHYDALESRFWQFYPRMMVQAKNKQL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.
Protein: AT13B_ARATH
Sequence: MSSSHNRSNNNNSEGAKAEQIIFEFFAKSLHIILESRTPFMSSRNFSGEQMICSPSSSSSSSSSVRPRDKWFNLALRECPAALESFDIGRRSSLEPLVVDVVLVVRPLVGDQSGKRELIRNFSGKDYQSGWNSDQDELGCETKNEQIIERWVVQYDNRKIRESVTTSSRRSSSNKLQVMYKKATLLLRSLFVMVRLLPAYKIFRELNSSGQIFKFKLVPRVPSIVEPFTRKEEAEMQKFSFTPVETICGRLCLSVLYRSLSDVSCEHSTPMSPTFITDYVGSPLADPLKRFPSLPLSYGSPPLLPFQRRHSWSFDRYKASPPSVSCSPSPTRSDSHALVSHPCSRHLPPHPSDIPTGRRKESYPEEYSPCQDFSPPPSPSAPKHAVPRGITRTESAPVRIPAPTFQSKENVVAPSAHLKLSRHASLKPVRNLGPGESGAAIDKLFLYGRDDFRRPSGVRPSSSSSPRISFSRSSSRSFQDDFDDPDFPCPFDVEYDDITDRNSRPGSFDHRGDIHEPFDSSGSYPKKSQDAAVGALVRMLKKAPPLRQDVSESSRPEICSNNNKPAGAHEIAVASITASGIALASKTTADALEELRSYKEMKNHLLLGQSTSNPSSVTITSPFDV
What is the function of this protein?
Involved in autophagy in a nutritional condition dependent manner.  The ATG1-ATG13 protein kinase complex regulates downstream events required for autophagosome enclosure and/or vacuolar delivery.  Becomes a target of autophagy under nutrient starvation (By similarity).  Connects autophagy to plant nutritional status (PubMed:21984698).
What are the official names of this protein?
Autophagy-related protein 13b, AtAPG13b.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Plant subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome.
Protein: MIAA_HELPG
Sequence: MDAEIFSLDSLSIYKDINIASAKPSLKERKNIKHYALDYLNIDEKNNAQLFKTLLEDAMRVSSKEILLIVGGSSFYLKSILEGLSDTPKISGEEVVKIEREIATLSNPYIFLKSIDPNMAFKIHSNDTYRIHKALEIFYATHTPPSEYFKANPKKPFAHAISLFALSVEKNALHNNIKQRTKNMLHSGLIEEIKALYTQYPKDSQPFKAIGVKESILFLEKRLTLKELEETITSNTIKLAKRQNTFNKTQFNNLYTGSVKEVRHAILKHSKSGIKG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ATPE_NATTJ
Sequence: MARKEFQLEIVTPERIVYSDKVVSITAQAEDGRLGILHDHRPLVTKLQIAPFSFITQEGQEENVAISGSGYLEVTPQKVTVLCQTAELSHEIELERAQEAKERAEERLQASDEAIDYSRAEASLKRAIARIDAARAQRNDD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MDH_MYCA1
Sequence: MSASPLKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALKALEGVVMELDDCAFPLLSGVEIGADPNKIFDGANLALLVGARPRGPGMERSDLLEANGAIFTAQGKALNEVAADDIRVGVTGNPANTNALIAMSNAPDIPRERFSALTRLDHNRAISQLAKKTGAKVTDITKMTIWGNHSATQYPDIFHAEVKGKNAAEVVGDQNWIENDFIPTVAKRGAAIIDARGASSAASAASATTDAARDWLLGTPAGDWVSMAVISDGSYGVPEGLISSFPVTTKDGDWTIVQGLEIDEFSRSRIDKTTAELADERNAVTQLGLI
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: NCTR1_HUMAN
Sequence: MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQLHFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEMYDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLAPEDPTFPADTWGTYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASRASTWEGRRRLNTQTL
What is the function of this protein?
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
What are the official names of this protein?
Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46.
What is the protein family that this protein belongs to?
Belongs to the natural cytotoxicity receptor (NCR) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ODP1_MYCTU
Sequence: MTTDFARHDLAQNSNSASEPDRVRVIREGVASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVNTIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPGA
What is the function of this protein?
Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  AceE has reductase activity with pyruvate but does not react with 2-oxoglutarate.
What are the official names of this protein?
Pyruvate dehydrogenase E1 component, PDH E1 component.
Protein: SYFA_DELAS
Sequence: MNELDSLVESAQQLFAQAQTPADLENAKAQFLGKSGKVTELMKGMAQLSVEEKKSRGAAINVAKQGIEAALTARRKALADAELQAHLKAEVLDVTLPGRRRGQGGLHPVSLTLERIEGIFGSMGFDVAEGPEIESDWFNFTALNTPEDHPARSMHDTFYVEGGTEQAPNLLRTHTSPMQVRHAVQHVKKYRERLDAGQGMPEIRVIAPGRTYRVDSDATHSPMFHQCEGLWIGENVSFKDLKVVFTDFCKTFFESDDLVLRFRPSFFPFTEPSAEIDIQFQSGPLAGRWLEVAGSGQVHPNVVRNMGLDPEKYIGFAFGMGPDRLTMLRYGVNDLRLFFDGDIRFLSQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICK41_TRILK
Sequence: MKPIVYMLLFCAFTVVILGHPNNHGALIPHHDKLPNGESCTRPGYSCSESSQCCTPVDGETFTYGCGRAWMEGSKICYICNRESSMC
What is the function of this protein?
Probable neurotoxin with ion channel impairing activity.
What are the official names of this protein?
Toxin ICK-41.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 27 (Jztx-72) family. ICK-41 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LOLB_SHELP
Sequence: MNNLNYFTKISASCAALALMTLAGCASHKPIDYAPTQVESANQAEAWELQGKLAVRTPEDKFSTNLYWFHTQTNDDLTLTTMLGTTVMTLNKTPSQASLQIEDKVYQDSDAEELLRRLTGWSIPVDTLPLWITGQVSAQDEVVAVDEQGRPKEVLNHTGSSPWHVSFNSWQEQSGAELPRLLQLERDDIRLKLQVSQWQALTPKRASQPESTDDKQ
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: POT7_ARATH
Sequence: MAEESSMEGSEKEEIDSSGGGFGDMASMDSIESRWVIQDDDDSEIGVDDDNDGFDGTGLESDEDEIPEHRLIRTGPRVDSFDVEALEVPGAPRNDYEDLTVGRKVLLAFQTLGVVFGDVGTSPLYTFSVMFSKSPVQEKEDVIGALSLVLYTLLLVPLIKYVLVVLWANDDGEGGTFALYSLISRHAKISLIPNQLRSDTRISSFRLKVPCPELERSLKLKEKLENSLILKKILLVLVLAGTSMVIADGVVTPAMSVMSAVGGLKVGVDVVEQDQVVMISVAFLVILFSLQKYGTSKMGLVVGPALLIWFCSLAGIGIYNLIKYDSSVYRAFNPVHIYYFFKRNSINAWYALGGCILCATGSEALFADLCYFSVRSVQLTFVCLVLPCLMLGYMGQAAYLMENHADASQAFFSSVPGSAFWPVLFIANIAALIASRTMTTATFSCIKQSTALGCFPRLKIIHTSRKFMGQIYIPVLNWFLLAVCLVVVCSISSIDEIGNAYGMAELGVMMTTTILVTLIMLLIWQINIVIVIAFLVVFLGVELVFFSSVIASVGDGSWIILVFAVIMFGIMYIWNYGSKLRYETEVEQKLSMDLMRELGCNLGTIRAPGIGLLYNELVKGVPAIFGHFLTTLPAIHSMVIFVCIKYVPVPVVPQNERFLFRRVCTKSYHLFRCIARYGYKDARKETHQAFEQLLIESLEKFIRREAQERSLESDGNDDSDSEEDFPGSRVVIGPNGSMYSMGVPLLSEYRDLNKPIMEMNTSSDHTNHHPFDTSSDSSVSEAEQSLERELSFIHKAKESGVVYLLGHGDIRARKDSWFIKKLVINYFYTFLRKNCRRGIANLSVPQSHLMQVGMTYMV
What is the function of this protein?
Probable potassium transporter.
What are the official names of this protein?
Potassium transporter 7, AtHAK7, AtPOT7.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPA_CALS4
Sequence: MGIRPEEISSVLAEKIKNFDFSVETQEIGYVIQSGDGIARIYGLDNAVYGEMVEFESGVVGMVLNLEEDTVGVVVLGDPEKVKEGDVVKRTGRIMEVPVGKGLLGRVVNPLGEPIDGKGPIEYEGKRPIESPAPPIVRRQPVNTPLQTGILAIDSMIPIGRGQRELIIGDRQTGKTAIAVDTIINQKDKGVYCIYVAIGQKASTVASVVNTLEKYGAMEYTTVVAATASESAALQYIAPYAGCAMGEHFMYQGKDVLVVYDDLSKHAVAYRTLSLLLRRPPGREAYPGDVFYLHSRLLERSARLSDEYGGGSLTALPIVETQAGDISAYIPTNVISITDGQIYLESELFYSGIRPAINVGLSVSRVGGAAQIKAMKKVAGRLRLELSQYRELQVFARFGTDLDKATLEVLRQGERIVEITKQPQYQPMAVEDQVIAIYTVMNRYVTDIEVSEVRPFVMGLLKFLDEAYPEIKQSIRDTKDLTKETEEKLKAAILEYKEKYAAKGEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: STE7_YEAST
Sequence: MFQRKTLQRRNLKGLNLNLHPDVGNNGQLQEKTETHQGQSRIEGHVMSNINAIQNNSNLFLRRGIKKKLTLDAFGDDQAISKPNTVVIQQPQNEPVLVLSSLSQSPCVSSSSSLSTPCIIDAYSNNFGLSPSSTNSTPSTIQGLSNIATPVENEHSISLPPLEESLSPAAADLKDTLSGTSNGNYIQLQDLVQLGKIGAGNSGTVVKALHVPDSKIVAKKTIPVEQNNSTIINQLVRELSIVKNVKPHENIITFYGAYYNQHINNEIIILMEYSDCGSLDKILSVYKRFVQRGTVSSKKTWFNELTISKIAYGVLNGLDHLYRQYKIIHRDIKPSNVLINSKGQIKLCDFGVSKKLINSIADTFVGTSTYMSPERIQGNVYSIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQRIVNEPSPRLPKDRIYSKEMTDFVNRCCIKNERERSSIHELLHHDLIMKYVSPSKDDKFRHWCRKIKSKIKEDKRIKREALDRAKLEKKQSERSTH
What is the function of this protein?
Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast.  It is thought that it is phosphorylated by the ste11 protein kinase and that it can phosphorylate the FUS3 and or KSS1 kinases.
What are the official names of this protein?
Serine/threonine-protein kinase STE7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: MSRB_PECCP
Sequence: MTNDSASRTPSDNTELTEMQRYVTQQRGTEPAFSGKLLHNKRTGVYHCLCCQAPLFYSDSKYDSGCGWPSFDQPVSSEAVRYLEDDSHNMRRIEIRCGQCDAHLGHVFPDGPKTTGERYCVNSASLSFIDDVDGERVDG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: NSP3_ROTHT
Sequence: MLKMESTQQMVSSIINTSFEAAVVAATSTLELMGIQYDYNEVFTRVKSKFDYVMDDSGVKNNLLGKAITIAQALNGKFGSAIRNRNWMSDSKTVAKLDEDVNKLRMTLSSKGIDQKMRVLNACFSVKRIPGKSSSIIKCTRLMKDKIERGEVEVDDSYVDEKMEIDTIDWKSRYDQLEKRFESLKQRVNEKYNTWVQKAKKVNENMYSLQNVISQQQNQIADLQQYCNKLEADLQGKFSSLVSSVEWYLRSMELPDDVKTDIEQQLNSIDLINPINAIDDIESLIRNLIQDYDRTFLMLKGLLKQCNYEYAYE
What is the function of this protein?
Plays an important role in stimulating the translation of viral mRNAs.  These mRNAs are capped but not polyadenylated, instead terminating in a conserved sequence 'GACC' at the 3' that is recognized by NSP3, which competes with host PABPC1 for EIF4G1 binding.  The interaction between NSP3 and host EIF4G1 stabilizes the EIF4E-EIF4G1 interaction, thereby facilitating the initiation of capped mRNA translation.
What are the official names of this protein?
Non-structural protein 3, NSP3, NCVP4, Non-structural RNA-binding protein 34, NS34.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP3 family.
What are the subcellular locations of this protein?
Host cytoplasm.