PharMolix/UniProtQA huggingface dataset:
Protein: MRF4_ARATH
Sequence: MATREWFVMNAQQTKLALESPPLFAVKKDDDKDHTCDTGEEPYALVGSPVFNPLEDYKREVVSIIDEYFSSGDVEVAASDLMDLGLSEYHPYFVKRLVSMAMDRGNKEKEKASVLLSRLYALVVSPDQIRVGFIRLLESVGDLALDIPDAVNVLALFIARAIVDEILPPVFLARAKKTLPHSSQGFQVILVSENSYLSAPHHAELVETKWGGSTHITVEETKRKISEFLNEYVENGDTREACRCIRELGVSFFHHEIVKSGLVLVMESRTSEPLILKLLKEATEEGLISSSQMAKGFSRVADSLDDLSLDIPSAKTLFESIVPKAIIGGWLDEDSFKERSDQNGGSENLRRFKKDAETIIQEYFLSDDIPELIRSLEDLGLPEYNPVFLKKLITLAMDRKNKEKEMASVFLASLHMEMFSTEDFINGFIMLLESAEDTALDILAASDELALFLARAVIDDVLAPLNLEEISNSLPPKSTGSETIRSARSLISARHAGERLLRSWGGGTGWAVEDAKDKIWKLLEEYEVGGVISEACRCIRDLGMPFFNHEVVKKALVMAMEKKNDRMLNLLQECFAEGIITTNQMTKGFGRVKDSLDDLSLDIPNAEEKFNSYVAHAEENGWLHRDFGCSTDS
What is the function of this protein?
Involved in target of rapamycin (TOR)-regulated translation control, especially under energy-deficient conditions.
What are the official names of this protein?
MA3 DOMAIN-CONTAINING TRANSLATION REGULATORY FACTOR 4, MA3 domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the PDCD4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: RS12_BACFN
Sequence: MPTIQQLVRKGREVLVEKSKSPALDSCPQRRGVCVRVYTTTPKKPNSAMRKVARVRLTNQKEVNSYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGTLDTAGVAGRTQRRSKYGAKRPKPGQAAPAKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TGIF1_PANTR
Sequence: MVLAQSRVSAGVGSPHCSGSGGGGSDYFPWPASHPGNPQCSFSTAFLASPRLSRGTLAYLPPALWSSLATPSALLGSSCAPPPPPARCPQPRALSPELGTKAGPRRPHRWELPRSPSQGAQGPAPRRRLMETMKGIVAASGSETEDEDSMDIPLDLSSSAGSGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLSTLQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGAKISETSSVESVMGIKNFMPALEETPFHSCTAGPNPTLGRPLSPKPSSPGSVLARPSVICHTTVTALKDVPFSLCQSVGVGQSTDIQQIAANNFTDTSLMYPEDTCKSGPSTNTQSGLFNTPPPTPPDLNQDFSGFQLLVDVALKRAAEMELQAKLTA
What is the function of this protein?
Binds to a retinoid X receptor (RXR) responsive element from the cellular retinol-binding protein II promoter (CRBPII-RXRE).  Inhibits the 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element.  Active transcriptional corepressor of SMAD2.  Links the nodal signaling pathway to the bifurcation of the forebrain and the establishment of ventral midline structures.  May participate in the transmission of nuclear signals during development and in the adult, as illustrated by the down-modulation of the RXR alpha activities (By similarity).
What are the official names of this protein?
Homeobox protein TGIF1, 5'-TG-3'-interacting factor 1.
What is the protein family that this protein belongs to?
Belongs to the TALE/TGIF homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IRX3_XENLA
Sequence: MSFPQLGYQYIRPLYPSDRQSVGVTRSGTELSPAGTLSNVLSSVYGAPYAAAAAAQAYGAFLPYSAELPIFPQLGSQYDMKDSPGVQHAAFSHPHPAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLKKENKMTWAPRSRTDEEGNAYGSDHEEDKHEDEEEIDLENIDTEDIESKEDLDDPDTDIHSDSKTDTRSDSEVSDGFEDLNVPEDRLLKSVVGQRQLLNEEPQDKCALSSDAKVPQPACEQIKLNRLPPSPPQENNMPVAHKPKIWSLAETATTPDNPRNSPNTGGSVNTQNLIAQHRLIASPGSRFQGWTGRAFSAQQLSLLNSAHFLQGLGVSHTAPCSGNASFPKAAESKCSTNSLTDRPSTVDIEKTIPVLNTAFQPVQRRSQNHLDAAMILSALSSS
What is the function of this protein?
Acts partially redundantly with other irx members in neural patterning.  Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord.  Both up-regulates and down-regulates gene expression during neural development.  Acts early in neural plate development to induce proneural gene expression and specify a neural precursor state.  Also up-regulates repressors that prevent neuronal differentiation.  Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling.  Subsequently required for proper formation of the intermediate tubule segment of the pronephros.
What are the official names of this protein?
Iroquois-class homeodomain protein irx-3, Iroquois homeobox protein 3, Xiro3.
What is the protein family that this protein belongs to?
Belongs to the TALE/IRO homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYFA_BIFLS
Sequence: MAEQMVFDADQVTAEVAEGIEKIQNASNLEELKAIKTTYAGADSAMTKASKAIGSLPADQKKEAGKLMGKLRADFGRAYGPKEVELKEAAEKAALAAETVDMTLPVNRKPLGARHPLPKLMEDVEDFFISMGWQISSGLEIEAEWYNFDSLNFGPDHPARQMQDTFYVKGNQAKDAAGFVGSNMVVRTQTSSDQVRALLTRGVPLYIASPGRVFRTDELDATHTPVFHQCEALAVDKHLTMADLKGVLDKLAVAMFGPEAKTRLRPSYFPFTEPSAELDLWFPDKKGGPGWLEWGGCGMVNPNVLKSAGIDPDVYTGFAFGVGMERTLLLRSDINDMHDLVEGDVRFAEQFVMGE
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEN15_HUMAN
Sequence: MEERGDSEPTPGCSGLGPGGVRGFGDGGGAPSWAPEDAWMGTHPKYLEMMELDIGDATQVYVAFLVYLDLMESKSWHEVNCVGLPELQLICLVGTEIEGEGLQTVVPTPITASLSHNRIREILKASRKLQGDPDLPMSFTLAIVESDSTIVYYKLTDGFMLPDPQNISLRR
What is the function of this protein?
Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini (PubMed:15109492, PubMed:27392077).  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  The tRNA splicing endonuclease is also involved in mRNA processing via its association with pre-mRNA 3'-end processing factors, establishing a link between pre-tRNA splicing and pre-mRNA 3'-end formation, suggesting that the endonuclease subunits function in multiple RNA-processing events (PubMed:15109492).
What are the official names of this protein?
tRNA-splicing endonuclease subunit Sen15, SEN15 homolog, HsSEN15, tRNA-intron endonuclease Sen15.
What is the protein family that this protein belongs to?
Belongs to the SEN15 family.
Protein: TRPD_BORPD
Sequence: MTITPAEALTRCIEHREIFHDEMLHLMRMLMRGEMSPQIASALLMGLRVKKETVGEITAAAQVMREFATPVVTPNPQDLLDMCGTGGDGSHTFNISTTAMFVAAAAGVPIAKHGGRSASSSSGSADVLEALGANLTLSPEQVAECIQATGIGFMFAPAHHSAMKNVAPVRKELGVRTIFNILGPLTNPANAANQLMGVFHPDLVGIQVRVLQRLGSRHVLIVHGKDGMDEASLGSATLVGELKDGEIREYEIHPEDYGLSMVSNRGIKVANREESRELVIQALDNVEGVARDIVALNAGLAIYAGNKTDTIGQALSLAFETISNGSARAKLEEFCAYTRKFQK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ISPG_VIBVU
Sequence: MHNESPIIRRKSTRIYVGDVPIGDGAPIAVQSMTNTRTTDVAATVAQIKALENVGADIVRVSVPTMDAAEAFKLIKQQVSIPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVDCARDKNIPIRIGVNGGSLEKDLQMKYGEPTPEALVESAMRHVDILDRLNFDQFKVSVKASDVFLAVDSYRLLAKKIDQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRISLAANPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNALEERLEDIITPMDVSIIGCVVNGPGEAEVSHLGLAGSNKKSAFYEDGKRQKERFDNEDLVNQLEAKIRAKAARMDESNRIDIKVQN
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RL23_HELPS
Sequence: MADIMDIKSILYTEKSLGLQEKGVLVVQTAQNVTKNQLKEVFKTYFGFEPLKINSLKQEGKVKRFRGKLGQRKSFKKFYVKVPEGASIAALGA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: YCJF_SHISS
Sequence: MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDEAPEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWQCLWCLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KIN17_MOUSE
Sequence: MGKSDFLSPKAIANRIKSKGLQKLRWYCQMCQKQCRDENGFKCHCMSESHQRQLLLASENPQQFMDYFSEEFRNDFLELLRRRFGTKRVHNNIVYNEYISHREHIHMNATQWETLTDFTKWLGREGLCKVDETPKGWYIQYIDRDPETIRRQLELEKKKKQDLDDEEKTAKFIEEQVRRGLEGKEQETPVFTELSRENEEEKVTFNLNKGAGGSAGATTSKSSSLGPSALKLLGSAASGKRKESSQSSAQPAKKKKSALDEIMELEEEKKRTARTDAWLQPGIVVKIITKKLGEKYHKKKGVVKEVIDRYTAVVKMTDSGDRLKLDQTHLETVIPAPGKRVLVLNGGYRGNEGTLESINEKAFSATIVIETGPLKGRRVEGIQYEDISKLA
What is the function of this protein?
Involved in DNA replication and the cellular response to DNA damage.  May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes.  May play a role in illegitimate recombination and regulation of gene expression.  May participate in mRNA processing.  Binds, in vitro, to double-stranded DNA.  Also shown to bind preferentially to curved DNA in vitro and in vivo.  Binds via its C-terminal domain to RNA in vitro.
What are the official names of this protein?
DNA/RNA-binding protein KIN17, Binding to curved DNA, KIN, antigenic determinant of recA protein.
What is the protein family that this protein belongs to?
Belongs to the KIN17 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=During S phase, strongly associated with the nuclear matrix, and to chromosomal DNA in the presence of DNA damage. Also shows cytoplasmic localization in elongated spermatids.
Protein: NUCS_MYCVP
Sequence: MRLVIAQCTVDYVGRLTAHLPSARRLLLFKADGSVSVHADDRAYKPLNWMSPPCWIVEPTDGDATVWVVENKAGEQLRITVEAIEHDSSHELGVDPGLVKDGVEAHLQALLAEHVELLGAGYTLVRREYMTPIGPVDLLCRDEQGRSVAVEIKRRGEIDGVEQLTRYLELLNRDSLLAPVAGVFAAQQIKPQARTLATDRGIRCLTLDYDKMRGMDNDEFRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFA3_ORNAN
Sequence: MRTLGLLLALLFLAAQTPAQLMGEEAEEATGRPEATEAQEAAAALMAARAADRHVTDPEQQRIITCSCRTFCFLGERISGRCYQSVFIYRLCCRG
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Defensin-A3, DefA3, OaDefA3.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GP180_MOUSE
Sequence: MGGLRLLAVALTCSCWWPQGGQGKTLRGSFSSAAARDAQGQSIGHFEFHGDHALLCVRINNVAVAVGKEAKLYLFQAQEWLKLLESSPGYSCSERLARAQLTVTVTQTEHNLTVSQLPAPQTWRVFYADKFTCRDDSESPQGEEIPFEMVLLNPDAEGNPLDHFSARESGLHEFFFLLVLVYFVTACIYAQSLWQAMKKGGPMHTILKVLTTALLLQAASALANYIHLSRYSRDGLGVPLIGSLAEVFDIASQIQMLYLLLSLCMGWTIVRMKKSQSRPLQWDSTPASTGIAVFIVITQSILLLWEQFEDTSHHSAHSHRSLAGLLLIVLRICLALSLGCGLYQVITVERSALKREFYITFAKGCILWFLCQPALACIAVAFNDYQRDKLITVGVILCQAVAMVILYRLFLSHSLYWEVSSLSSVTLPLTISSAHRGRPHF
What are the official names of this protein?
Integral membrane protein GPR180.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RM24_CAEBR
Sequence: MITSRVLRFPRKPFVDLDYSRHMPAAYVERTKRTVPRKVFGDRFGAPDIKMYYVHPDDYLPSHRRPWEDKQLSSHLQRSDKYFSAQLSNKYFELRRPKSERMPDTEWTFFPGDLVQVMVGKDKGRQGLVLTISRDSSEVVVDGLHTRLGEDMEGSEKLGVDKTLRWQEQPLSVSKKQVMLVDPNDENPCEARWQLNASADEYIRVSTRSGYEIPIPSQAKVTYEYLQPENYIEVEGKDTPSDAVLERTYMPRVASFEQEIMEEMGIKEDRTPKPTFWY
What are the official names of this protein?
Probable 39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ATPB_BIFLO
Sequence: MADNQTTAAEPTNGRVTRVQGSVIDVEFPVGHLPDIYNALKVTIVNTSAKEEGEAKETEITLEVEQHLGDSTVRCVALKPTDGLVRGASVSDTGAPISVPVGDVTKGHVFDVSGNILNKKPDETITVSERWPIHRNPPAFDQLESKTQMFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQNHGGVSVFAGVGERTREGNDLIGEMAEAGVLEKTALVFGQMDEQPGTRLRVPLTALTMAEYFRDVQNQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPNLADEMGSLQERITSTRGHSITSLQAIYVPADDYTDPAPATTFAHLDATTELSRDIASKGIYPAVDPLSSTSRILDPRYVGQAHYDCANRVKAILQRNKELQDIIALIGIDELGEEDKTTVNRARKIEQFLGQNFYVAEKFTGRPGSYVPADETIEAFTRICDGVYDDVPEQAFSGIGGIDDLEEKWHNMQKELGA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPA_YERE8
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGIIRVHGLADVMQGEMIALPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGEPVDGKGPVENDGFSAVEAIAPGVIERQSVDEPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTVANVVRKLEEHGALANTIVVVATASESAALQYLAPYSGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLSHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLGDIELAKVGSFEAALLAFADREHAELLQQINQTGAYNDEIEAKLKGILDTFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNAK_SYNC1
Sequence: MGKVIGIDLGTTNSCVAVMEGGEPVVIANAEGSRTTPSMVAFTENGERLVGQQAKRQAVTNPENTLFAIKRLIGRKFDSDAVRRDIQISPFEIVKADNGDAWVDVRDKKYSPPEISAMILQKMKQTAEDYLGEKVTDAVITVPAYFNDSQRQATKDAGKISGLNVLRIINEPTAASLAYGLDKKSEEKIAVFDLGGGTFDISILELGDGVFEVKSTNGDTFLGGEDFDQHIMDYVADEFKKEQGIDLRNDKMALQRLKEACEKAKCELSTSMETDINLPFITADQSGPKHLNLRLTRSKLESICSSLLAKLVEPCRMALKDAGLSASDVDEVLLVGGMTRMPAVQAKVQEIFGKTPNKGVNPDEVVAIGAAIQGGVLKGEVKDVLLLDVTPLSLGIETLGSIMTKLIEKNTTIPCKKSQIFSTAADNQPAVSVHVLQGEREMAGDNKTIGRFELVGIPPAPRGVPQVEVTFDIDANGILHVSAKDLGTGKEQSIRITASSGLSDEEIDKMVKDAEAHSSEDKKKREIIEARNQADGLAYSTEKSLKEHGDKIDEETRNNIQTALDALKAAMEGDDPEDIRQKSEALATASHKLAEAVYKQTQEGAEAASEAGEQSAGDEGVVDAEFEEVDEQNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y379_HAEIN
Sequence: MKLTSKGRYAVTAVLDIALNADGGPVSLADISERQHISLSYLEQLFAKLRKDGLVKSVRGPGGGYQLGLPSEQISVGMIIAAVNENIHVTKCLGRENCKNGVECLTHELWEDLSLRIESFLNEITLAELVNKRNVKRQSHRDFNNLLVNQ
What are the official names of this protein?
Putative HTH-type transcriptional regulator HI_0379.
Protein: MUTS_BACCN
Sequence: MAQYTPMIQQYLKVKADYKDAFLFFRLGDFYEMFFEDAVKAAHELEITLTSRDGGSSERIPMCGVPYHAAQNYIEQLIEKGYKVAICEQVEDPKTAKGVVRREVVQLITPGTMMEGRTIDEKENNFLAALTRFEDGSYALACNDLTTGQNTVTLLTGSVEDVLLEVYATGSKEIVVDSTFSQDELNKLTETLKMTVSYEEETKIPEGLEPLVKKVTQTKLVTAVGRLFNYVLRTQKRSLDHLQPVEIYYTNQFMKIDVHSKRNLELTETLRTKEKTGSLLWLLDKTKTAMGGRMLKQWMERPLIQKEKIEERLEMVETFVNDYFLREDLKEKLKEVYDLERLAGKVAYGSVNARDLLQLKRSLQQVPAILEAISLLDNSYAAKLIEGADPCEALTKLLDRSIQENPPLSVKDGDIIKDGYNEKLDEYRYISKNGKTWIAELEKREREITGIKSLKIGYNRIFGYYIEVTKANLSLLPEGRYERKQTLANAERFITDELKEKETLILEAEEKIVQLEYDLFTALREEVKVFIPKLQHLAKVISELDVLQSFATVSEEERFVKPVLTNKREIFIKDGRHPVVEKVLDGKLYVPNDCMMPENMDVFLITGPNMSGKSTYMRQLALVTIMAQIGCFVPATEAILPVFDQIFTRIGAADDLISGQSTFMVEMLEAKNAIANASERSLILFDEIGRGTSTYDGMALAQAIIEHIHDQIGAKTLFSTHYHELTVLEESLTHLKNVHVSAIEEDGKVVFLHKIQEGAADKSYGIHVAQLAELPDSLIARAKEVLAQLEGQEEITIPKRTEVKEQPERMQQPVIEEQPVIKEVAEVQQESEEIVEESQLSFFETEERMEKQEKPVLDAKETAVLAQIKKIDLLDMTPLEALNELYRLQKKLKKG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: UVRY_ECO57
Sequence: MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLMITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
What is the function of this protein?
Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system.  UvrY activates the transcription of the untranslated csrB RNA and of barA, in an autoregulatory loop.  Mediates the effects of CsrA on csrB RNA by BarA-dependent and BarA-independent mechanisms (By similarity).
What are the official names of this protein?
Response regulator UvrY.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_VIBVY
Sequence: MLSGQTVVSIQPVVGSPLDKTEFIVAMAVAAEQAGAKALRIEGVENVRHVSQATNVPIIGIVKRDLQDSPVRITPFVCDVDALATAGATIIAFDATDRQRPESRETIANAIKNSGCFAMADCSCFADGQWAAQIGVDIIGSTLSGYVGEIEPTEPDLELVKQFSSAGFFTMAEGRYNTPQLAAKAIENGAVAVTVGSAITRMEVVTHWFNSATQAVRQNNESISY
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: CRYM_RAT
Sequence: MRRAPAFLSADEVQDHLRSSSLLIPPLEAALANFSKGPDGGVMQPVRTVVPVAKHRGFLGVMPAYSAAEDALTTKLVTFYEGHSNNAVPSHQASVLLFDPSNGSLLAVMDGNVITAKRTAAVSAIATKFLKPPGSDVLCILGAGVQAYSHYEIFTEQFSFKEVRMWNRTRENAEKFASSVQGDVRVCSSVQEAVTGADVIITVTMATEPILFGEWVKPGAHINAVGASRPDWRELDDELMKQAVLYVDSREAALKESGDVLLSGADIFAELGEVVSGAKPAYCEKTTVFKSLGMAVEDLVAAKLVYDSWSSGK
What is the function of this protein?
Specifically catalyzes the reduction of imine bonds in brain substrates that may include cystathionine ketimine (CysK) and lanthionine ketimine (LK).  Binds thyroid hormone which is a strong reversible inhibitor.  Presumably involved in the regulation of the free intracellular concentration of triiodothyronine and access to its nuclear receptors (By similarity).
What are the official names of this protein?
Ketimine reductase mu-crystallin, CDK108, NADP-regulated thyroid-hormone-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ornithine cyclodeaminase/mu-crystallin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BORPA
Sequence: MPRVKRGVTARARHKKVIAAAKGYRGRRGNVFRIAKQAVMRAGQYAYRDRRNKKRTFRALWITRINAAVREQGMSYSVFIAGLKKAAIELDRKVLADLAVRDKAGFAAIVQQAKAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: EPSL_BACSU
Sequence: MILKRLFDLTAAIFLLCCTSVIILFTIAVVRLKIGSPVFFKQVRPGLHGKPFTLYKFRTMTDERDSKGNLLPDEVRLTKTGRLIRKLSIDELPQLLNVLKGDLSLVGPRPLLMDYLPLYTEKQARRHEVKPGITGWAQINGRNAISWEKKFELDVWYVDNWSFFLDLKILCLTVRKVLVSEGIQQTNHVTAERFTGSGDVSS
What is the function of this protein?
May be involved in the production of the exopolysaccharide (EPS) component of the extracellular matrix during biofilm formation.  EPS is responsible for the adhesion of chains of cells into bundles.
What are the official names of this protein?
Uncharacterized sugar transferase EpsL.
What is the protein family that this protein belongs to?
Belongs to the bacterial sugar transferase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PPK1_BARHE
Sequence: MEKTVADQISLSDITMKNPARFINREFSWLQFNNRVLMEAANSKNPLLERLQFLSISATNLDEFFMVRVAGLAAQIRAGVTACSADGRTPQEQLDFVLAEISCLQDNQLRELSILRHELKQNNIEIICSAGLSETEKSWIEKYFLDTIFPVLTPLSVDPVRPFPFIPNLGFSIALQLSRCADQHSFIALLPLPTTLRRFIPLPQKDNRFRFIACEDVINLFMRHVFPDYEVEGIGTFRVIRDSDIEVEEEAEDLVHFFETALKRRRRGQVIRIEFEAKMPDHLRQFITNGLAVPEYCINVLDGFLALNTVSEIVSIPRNDLKFAPYDPRVPECICQHKGDCFAAIRQNDIVIHHPYESFDVVVEFLRQAARDPDVIEIKQTLYRTSNDSPIVSALIEAAEQGKSVTALVELKARFDEEANIRWARDLERAGVQVFFGFIALKTHAKMSLVVRREGKRRCSYVHLGTGNYHPINAKVYTDLSFFTTDDDIAHDVALLFNYIAEYVRPNEAMKIAFSPLTLRSRILEHIEGEITNARQGQLAAIWMKVNALVDPEIIDALYRASQAGVQIDLVVRGICCLRPGIPGISDNIRVKSIVGRFLEHSRIFCFGNGVNLPSENALVYFGSADMMPRNLDYRIEILVPVFNKMVRQQILLQVMLANIIDNQQSFDILNDGTSQLITPQRGESPFNAQEYFMANAGLSRMERSFDSSVSHLVALYQQKVKLYKD
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: GLGC_MYCMM
Sequence: MREAPHVLGIVLAGGEGKRLYPLTADRAKPAVPFGGAYRLIDFVLSNLVNARYLRICVLTQYKSHSLDRHISQNWRLSGLAGEYITPVPAQQRLGPRWYTGSADAIYQSLNLIYDEDPDYIVVFGADHVYRMDPEQMVRFHIDSGAGVTVAGIRVPRADASAFGCIDADDAGTIRDFVEKPLEPPGTPDDPTSTFVSMGNYVFTTKVLIDAIRADADDDHSDHDMGGDIIPRLVADGMAAVYDFSNNEVPGATDRDRAYWRDVGTLDAFYDAHMDLVSVHPVFNLYNKRWPIRGESENLAPAKFVNGGSAQESVVGAGSIISAASVRNSVLSSNVVVEDGAIVEGSVIMPGARVGRGAVVRHAILDKNVVVGPGEMVGVDLDKDRERFAISAGGVVAVGKGVWI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block, required in the biosynthesis of maltose-1-phosphate (M1P) and in the elongation reactions to produce linear alpha-1,4-glucans.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.