PharMolix/UniProtQA huggingface dataset:
Protein: TS1R3_HUMAN
Sequence: MLGPAVLGLSLWALLHPGTGAPLCLSQQLRMKGDYVLGGLFPLGEAEEAGLRSRTRPSSPVCTRFSSNGLLWALAMKMAVEEINNKSDLLPGLRLGYDLFDTCSEPVVAMKPSLMFLAKAGSRDIAAYCNYTQYQPRVLAVIGPHSSELAMVTGKFFSFFLMPQVSYGASMELLSARETFPSFFRTVPSDRVQLTAAAELLQEFGWNWVAALGSDDEYGRQGLSIFSALAAARGICIAHEGLVPLPRADDSRLGKVQDVLHQVNQSSVQVVLLFASVHAAHALFNYSISSRLSPKVWVASEAWLTSDLVMGLPGMAQMGTVLGFLQRGAQLHEFPQYVKTHLALATDPAFCSALGEREQGLEEDVVGQRCPQCDCITLQNVSAGLNHHQTFSVYAAVYSVAQALHNTLQCNASGCPAQDPVKPWQLLENMYNLTFHVGGLPLRFDSSGNVDMEYDLKLWVWQGSVPRLHDVGRFNGSLRTERLKIRWHTSDNQKPVSRCSRQCQEGQVRRVKGFHSCCYDCVDCEAGSYRQNPDDIACTFCGQDEWSPERSTRCFRRRSRFLAWGEPAVLLLLLLLSLALGLVLAALGLFVHHRDSPLVQASGGPLACFGLVCLGLVCLSVLLFPGQPSPARCLAQQPLSHLPLTGCLSTLFLQAAEIFVESELPLSWADRLSGCLRGPWAWLVVLLAMLVEVALCTWYLVAFPPEVVTDWHMLPTEALVHCRTRSWVSFGLAHATNATLAFLCFLGTFLVRSQPGCYNRARGLTFAMLAYFITWVSFVPLLANVQVVLRPAVQMGALLLCVLGILAAFHLPRCYLLMRQPGLNTPEFFLGGGPGDAQGQNDGNTGNQGKHE
What is the function of this protein?
Putative taste receptor.  TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate).  TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.  TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity).  Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.
What are the official names of this protein?
Taste receptor type 1 member 3, Sweet taste receptor T1R3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EPN2_RAT
Sequence: MTTSSIRRQMKNIVNSYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVWKRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGINVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATGVGSNQITFGRGSSQPNLSISHSEQEYGKAGGSPASYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERLRRGDDLRLQMALEESRRDTVKVPKKKEVKACCKPGSHSQQTTLLDLMDALPSSGPVAQKTEPWSTGTPANQTNPWGGTVAPANISDPWPSFGTKPAASVDPWGVPTTASIQSVPKNSDPWAASQQPASDAGKTADAWGAAKPSPASGSFELFSNFNGTVKDDFSEFDNLRTSKKPAESGASVPPQDSRTTSPDLFESQSLTSASSKPSSARKTPESFLGPNAALVNLDSLVTKPAPPAQSLNPFLAPGAAAPAPVNPFQVNQPQPLTLNQLRGSPVLGSSASFGSGPGVETVAPMPSVAPHSALGATGSSLTPLGPTAMNMVGSMGIPPSAAQPAGTTNPFLL
What is the function of this protein?
Plays a role in the formation of clathrin-coated invaginations and endocytosis.
What are the official names of this protein?
Epsin-2, EPS-15-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the epsin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=In punctate structures throughout the cell and particularly concentrated in the region of the Golgi complex.
Protein: SODF_PLAMA
Sequence: MVITLPKLKYALNALSPHISEETLNFHYNKHHAGYVNKLNTLIKDTPFAEKSLLDIVKESSGAIFNNAAQIWNHTFYWDSMGPDCGGEPHGGIKEKIQEDFGSFNNFKEQFSNILCGHFGSGWGWLALNNNNKLVILQTHDAGNPIKDNTGIPILTCDIWEHAYCIDYRNDRASYVKAWWNLVNWNFANENLKKAMQK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe], FeSOD.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_CITBB
Sequence: MSKQVLKAELREQTGKGICRRLRAAGRVPAVVYGKGIAPVSISLGQKELSEAIAGEGGRNHILTLECAGELNGASVIVADLLRDSLKNVPRHVDLHKINLADKVKVHVKLNLVGTPAGVKAGGFLDFAMHEVEVECLPVHIPAHINVDVAELLIGHSVHVGQIVAPIGTAILSDPKASVVSILGRKGAAEEEAAPAA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: Y952_PARP8
Sequence: MMKGQLAGLMKQAQQMQENMKKMQEQLAQIEVEGQSGAGLVKVTMTCKNDVRRVSIDPSLLADDKDMLEDLVAAAFNDAVRKAEATAQEKMGGMTSGLPLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Bphy_0952.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AKCL2_HUMAN
Sequence: MGDIPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFCLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGGSCEGVDLIDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLNRNLRLAMFPITKNHKDYPFHIEY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol (By similarity).  Has low NADPH-dependent reductase activity towards 9,10-phenanthrenequinone (in vitro) (PubMed:12604216, PubMed:15118078).
What are the official names of this protein?
1,5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member E2, LoopADR, Testis aldo-keto reductase, htAKR, Testis-specific protein, hTSP.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREG_CYTH3
Sequence: MTLLKMYRHLDHFDSPGHFHHRELIHEKRNFKKRAFTVGIGGPVGTGKTAWLMQICKALRDKMNIAVVTNDIFTSEDAEFLIRNEALSKDRIIGVETGGCPHAAIREDVSQNMYALEELMKRFPDVELLFVESGGDNLAAHFSKELVDYSVYVIDVSGGDKIPRKGGPGITQADLLVINKIDLAHLVNADLSVMERDSKKMRGDGPFLFARAKDCFGIDEIINHILTAREKALEAKPVYSLRKE
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLO8_CANAL
Sequence: MVPNTTKQVLNSLILDFLVKHQFQDTAKAFSKESPNLPSIPPLMDCSQGFLLEWWQVFFDLFQVRYGDGNSNNNPNNKLYHDYLRVQETQKHLFSQLPLIQQQQQQQHHFQQQQQQQGQQGQPFSQQQQRGIGVASGMQNQQHQFAPQHQGQPQGPGQTPQPPGSATNANFPINMPPNSNPQQQMFPINQQFAQMPNGQNQPSMEQQQRMAMMMKQQAMAAQRQQIPMNGLDPQQQQQMMNAVGGGPGNLNLQQQLFLQQQQQQQQQPKTTFQQQAQNQMNNLRQQAAMVAQQQQQQQQQQQQQGQLQGNLASAMGDSSSKNNSPVGARSNQQSTPQQNAAPAPSPHPSQQGQAQAQHNFQSQQQQQQQQMTKMAGSQGMKKNGQMSNGTSNNSSGRNNNALRDYQNQLMLLERQNKERLEFARNTGNSDSNPLSNGMMFAGQNQYSNSNQNQNQLPPNQQQPTPATFHPPPPPTTANGPQGQFNQKPSPATSNNSPALGNKSSPAMGNKKSKKESNSKKGKKANSNASTTANNKTSGQTTPNMSQPPSAGTEPKQPQPTEQMRQLQDKQQRPGSNTPSMGKKDFQPLTPRSEPISGETTKKKRKSGKLNDNNENSNGNSPKKQAKTNANSKNLDPIIKEEENGVLSLKKESSTSLQDQDLDLNPPLAPTQATAMSNTFNDDPFDVHLLDTQHHHQQNSNNSNHNRGQNLSNGSNNLSVSGPGMGMNNSVFGDSTHAFDINFNIDSLDDIWTTTGPGGDITGTGSGSGGAGGTDDDNFMGMNWAADPIENGD
What is the function of this protein?
Transcription factor which mediates CO(2) sensing.  Required for CO(2)-induced white-to-opaque switching, as well as for filamentous growth and virulence.  Required for both normoxic and hypoxic biofilm formation.  Hypoxic biofilm formation is a major cause of perseverance and antifungal resistance during infections.
What are the official names of this protein?
Transcriptional regulator of filamentous growth FLO8.
What is the protein family that this protein belongs to?
Belongs to the FLO8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RF2_LISMO
Sequence: MELAEIRNELEKTAQQIKDFRGSLDLDSMEVRIAELEDQMLDPNFWNDQQAAQKVINESNGYKETYQAFHALEEEQESMEISLELLKEEADEDLQEELEKDIKAYMATISAFELKLMLSDPYDKNNAILELHPGAGGTESQDWGSMLLRMYQRWSEKKGFKVEMLDYQAGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFVSVDVMPELDGDIEIEVRTEDLKIDTYRATGAGGQHINTTDSAVRMTHIPSGIVVTCQSERSQLKNREQAMKMLKTKLYQKEQEEKERELAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNYETGNIQAVMDGDLDDFINAYLRSRIG
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_CHAGL
Sequence: MARSIKKGPFVADHLIKKIENLNAKGEKKVIITWSRASTIVPMMIGHTIAVHNGREHLPVFVTDRMVGQKLGEFSPTRTFRGHVKSDKKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPX4_SPIOL
Sequence: MASDSSAQPKSVHEFVVRDARGNDVDLSIYKGKVLLIVNVASQCGLTNSNYTEMTELYEKYRELGLEILAFPCNQFGNQEPGSNEEVLEFACTRFKAEYPIFDKVDVNGSNAAPIYKFLKSSKGGLFGDGLKWNFTKFLVDKDGNVVDRYAPTTSPKSIEKDVKKLLGIQK
What is the function of this protein?
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.
What are the official names of this protein?
Probable phospholipid hydroperoxide glutathione peroxidase, PHGPx.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KOI_DROME
Sequence: MSENTYQIETRRRSRSKTPFLRSSCDHENCEHAGEEGHVHHLKRKSAAPNVQTIIEEHIVESSISKKTRAKAFAQLTSDYSSDDMTPDAKRKQNSITATVTSILTKRSGGATSTPRNRSQLETTQNTLNSAQEKLNQSNGNLSSGNVSDYLAYIEYRDAGEYWNKTPKTDYTYSELSPHRRQLAPGIVAMPNMSRKSLENHNDRVNYMVQQNPAQEEFIRRRYQSKYTQQVNYDSADELDATFGQQKQSWWLIRLIQLVVSSITTVWSRVTNLSATETTAYQNYHAKRQQSQQVGLWWKIVQTIGGGLASLLRYLYVFIGSVLSLDTWLLRSSDAENKSKKRFLIFLLILLPLLLLSGWLLLQEDQRSAYVQRAEALLPLPLSIFGSLRSRFSNAGATLKSWMEVPTVRSPQREAEAIKVNMASIEQNIQKALTAEEYENILNHVNSYVQQLVELKMQQHSKELAPQQIELFVKLMKENLKQIMYKTELSEKDLSDLAIKLKLELQSSGGWQDGAKLSQANLEEITKLIKAEVHLHESHYTIQLDRIDFASLLERILAAPALADFVDARISLRVGELEPKESSGSSDAEVQIERLNREIAFIKLALSDKQAENADLHQSISNLKLGQEDLLERIQQHELSQDRRFHGLLAEIENKLSALNDSQFALLNKQIKLSLVEILGFKQSTAGGSAGQLDDFDLQTWVRSMFVAKDYLEQQLLELNKRTNNNIRDEIERSSILLMSDISQRLKREILLVVEAKHNESTKALKGHIREEEVRQIVKTVLAIYDADKTGLVDFALESAGGQILSTRCTESYQTKSAQISVFGIPLWYPTNTPRVAISPNVQPGECWAFQGFPGFLVLKLNSLVYVTGFTLEHIPKSLSPTGRIESAPRNFTVWGLEQEKDQEPVLFGDYQFEDNGASLQYFAVQNLDIKRPYEIVELRIETNHGHPTYTCLYRFRVHGKPPAT
What is the function of this protein?
Component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton (By similarity).  Is required to nuclear migration in eye and to anchor klar in the nuclear membrane (PubMed:18820457).
What are the official names of this protein?
Klaroid protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Lam is required for perinuclear localization of Koi.
Protein: QUEA_LISW6
Sequence: MKVEDFDFDLPEELIAQTPLLDRTSSRLMVLDKKSGEIKDQHFTDILSYLNEGDALVLNDTRVLPARLHGTKDETGAHIEVLLLKQKEGNAWETLVKPAKRIRKGGTITFGNGALKATCLEELEHGGRILEFSYEGIFYEVLEQLGEMPLPPYIKEQLADQDRYQTVYAKENGSAAAPTAGLHFTEDLLAQISAKGVEIIFVTLHVGLGTFRPVDVEDTANHKMHSEFYRLTEDAANRINKIKATGGKVVAVGTTSIRTLETIASHNEGKLVAESGWTDIFISPGYTFQAVDALITNLHLPKSTLIMLVSALSNRTNILAAYNHAVEQQYRFFSFGDAMFIH
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCLF_SCHPO
Sequence: MSLRHSTQLIVQTVKLGLPTARKACSLPIQNPVVAANRFFASSVHSRNPQEEDVIPPKENASREDATDSEAYVRSDWDNTPIPELEKETAEKAASERQHSEKVTINDKTSPPSVDEM
What are the official names of this protein?
Uncharacterized protein C16A11.15c.
Protein: GRPE_PARXL
Sequence: MENTQENPTSQNPKPAEETARQAAEAAAPQQEAAANAATDSPASAEQAALAEAQAKIAELQESFLRAKAETENVRRRAQEDVAKAHKFAIESFAEHLLPVIDSLEAAVAHSSDDPAKVREGVELTLRQLTGALEKGRVVALNPVGEKFDPHRHQAISMVPADQEPNTVVAVLQKGFVIADRVLRPALVTVAAPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_ALIFM
Sequence: MQNKPSSYDREDLLASSRGELFGPNGPQLPAPNMLMMDRIPLMSETEGAFGKGKVIAELDITPDLWFFDCHFPGDPVMPGCLGLDAMWQLVGFFLGWIGGEGKGRALGVGEVKFTGQVLPTAKKVTYEIDFKRVINRKLVMGLADGRVLVDGKEIYVAKDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_PARUW
Sequence: MLQRKPKYNSDYSDARSKKRKRCPFTAAGIREIDYKDIDTLTKFITERGKILPRRITGVSAYHQKKLTAAIKRARHVALLPFVAEV
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FLGA_SALTY
Sequence: MQTLKRGFAVAALLFSPLTMAQDINAQLTTWFSQRLAGFSDEVVVTLRSSPNLLPSCEQPAFSMTGSAKLWGNVNVVARCANEKRYLQVNVQATGNYVAVAAPIARGGKLTPANVTLKRGRLDQLPPRTVLDIRQIQDAVSLRDLAPGQPVQLTMIRQAWRVKAGQRVQVIANGEGFSVNAEGQAMNNAAVAQNARVRMTSGQIVSGTVDSDGNILINL
What is the function of this protein?
Involved in the assembly process of the P-ring formation.  It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.
What are the official names of this protein?
Flagella basal body P-ring formation protein FlgA.
What is the protein family that this protein belongs to?
Belongs to the FlgA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYI_STRGC
Sequence: MKLKETLNLGKTDFPMRAGLPTKEPVWQKEWEEAKLYQRRQELNQGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPYIPGWDTHGLPIEQVLAKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYEAAQIRVFGEMAKKGYIYRGAKPVYWSWSSESALAEAEIEYHDLLSTSLYYANRVKDGKGVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGESRKFVVASELLNSLSEKFGWADVQVLATYRGQELNHIVTVHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGEDDYNVGVANGLEVAVTVNERGIMMENAGPEFAGQFYDKVVPTVIEKLGDLLLAQEEISHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTPIMTVETIEHVAQLFEEHGSIIWWERDAKDLLPEGFTHPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELKYPADLYLEGSDQYRGWFNSSLITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTSVDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAEDTVAYEELRSVDKYMTVRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQMQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAETFANQEEILNTWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTIYPNEVVKTLLGAVDSNVAQLLIVSELTIAEGGAPEGAVSFEDVAFTVERAAGEVCDRCRRIDPTTAERNYHAVICDHCASIVEENFADAVAEGFETK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_CAMJD
Sequence: MKLFGTDGVRGKAGEFLDSFLAMRLAMAAGIYFKDKSVTNNILVGKDTRRSGYMIENAIVSGLTSIGYNVIQIGPMPTPAIAFLTEDMRCDAGIMISASHNPYYDNGIKFFDTHGNKLSEDIEKKIEEIYFDDKLIQASKVDMEKIGQAKRIDDVIGRYIVSIKNSFPKDLTLKSLRVVLDVAHGAAYKVAPTVFKELGAEVIVMSDKPNGLNINENCGALHPVNLATEVKRLRADVGFAFDGDADRLVVVDEKGEVANGDSLLGVLALYLKEQGKLQSSVVATIVSNGALKEFLNKHGIELDTCNVGDKYVLEKLKANGGNFGGEQSGHIIFSDYAKTGDGLIVALQFSALMLSKKKSASSILGQVKLYPQLLTNLKIAEKKDLDKIKGLKELKKDLENKNINTLFRYSGTENLIRLLLEAKDIKLLEKEMKNVVEFFKKALNG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MRAY_LACJO
Sequence: MQFSLIPFISSFALTVIFLPLFIGFMRMKHEGQVIRDEGPKWHEKKSGTPTMGGVVFMLAGVISTLWVLIWQKDLNKTAWILIIAFLGYGIIGFLDDGIKLYFKRNLGLRAWQKLLGQIIIAALIITLAFSDHFAFELYIPFAGMVRNSFLFSLFVLFWLVGFSNAVNLSDGLDGLATGLSIIAYATYAWIAYQERNWVIVVFTLSVIGGLVGFFIFNHKPAKIFMGDAGSLALGGGLATVSIFLHRPWSLLLIGIVFVLETLSVILQVISFQTTGKRIFKMTPIHHHFEMLGWSEWKVDIVFWIVGLIGSIIYLIIWG
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: END8_ECOLU
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKSYQSQLIGQHVTHVETRGKALLTHFSNGLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTILLYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQVGLTGNHKAKDLSAAQLDALAHALLDIPRLSYATRGQVDENKHHGALFRFKVFHRDGEPCERCGSIIEKTTLSSRPFYWCPGCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: SURE_ROSDO
Sequence: MRILITNDDGINAPGLMVLHEIATRLAGQDGEVWTVAPAFEQSGVGHCISYTRPMMVAQMGPRRFAAEGSPADCVLAGLHDVMKDSPPDLVLSGVNRGNNSAENTLYSGTIGGAMEAALQGLPAIALSQYYGPRNNAIENPFEASAQHGVDVVQRILAHTPQETGGYRLFYNVNFPPVPGDEVLGIRLATQGFREGLGFSTEPHNAPSGRRFLWIKGGDQHRPTAPGSDAQLNLEGYISVTPMRADLTAHDMMAPLAGINT
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_LEIXX
Sequence: MSIIDHHSVVPRSEAAVGEDGRARTYEVRTFGCQMNVHDSERLSGSLEAAGYVPANGEEADIVVINTCAVRENADNKLYGNLGHLASVKRRHAGMQIAVGGCLAQKDKNVILEKAPWVDVVFGTHNMGALPRLLERARHNDAAEIEILEALETFPSTLPTKRDSSFSGWVSISVGCNNTCTFCIVPALRGKEKDRRPGDILAEVQALVDEGAVEVTLLGQNVNSYGVEFGDRQAFSKLLRAAGQIEGLERIRFTSPHPAAFTEDVIDAMAETPNVMPQLHMPLQSGSDRILRSMRRSYRSEKFLGILDRVRAKLPGAAISTDIIVGFPGETEEDFLDTLRVVEAARFASAFTFQYSIRPGTPAATMAGQVPKEVVQERYDRLIALQERISLEENEKLIGRDVELLVATGEGRKDADTRRLSGRARDSRLVHFELPAGSEVPRPGDVALVRVTQAAPHYLIADAAGGPLRVRRTRAGDAWDRAEAESCAAPSLSGGRAAAAVGRVSLGLPTLRTREPLTSPGVGTMPLYDPTDGQR
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLD_BACSU
Sequence: MGKKIRLTTAQALIKFLNQQYIHVDGKEEPFVEGIFTIFGHGNVLGIGQALEQDAGHLKVYQGKNEQGMAHAAMAYSKQMLRRKIYAVSTSVGPGAANLVAAAGTALANNIPVLLIPADTFATRQPDPVLQQMEQEYSAAITTNDALKPVSRYWDRITRPEQLMSSLLRAFEVMTDPAKAGPATICISQDVEGEAYDFDESFFVKRVHYIDRMQPSERELQGAAELIKSSKKPVILVGGGAKYSGARDELVAISEAYNIPLVETQAGKSTVEADFANNLGGMGITGTLAANKAARQADLIIGIGTRYTDFATSSKTAFDFDKAKFLNINVSRMQAYKLDAFQVVADAKVTLGKLHGLLEGYESEFGTTIRELKDEWLAERERLSKVTFKREAFDPEIKNHFSQEVLNEYADALNTELPQTTALLTINETIPEDSVIICSAGSLPGDLQRLWHSNVPNTYHLEYGYSCMGYEVSGTLGLKLAHPDREVYSIVGDGSFLMLHSELITAIQYNKKINVLLFDNSGFGCINNLQMDHGSGSYYCEFRTDDNQILNVDYAKVAEGYGAKTYRANTVEELKAALEDAKKQDVSTLIEMKVLPKTMTDGYDSWWHVGVAEVSEQESVQKAYEAKEKKLESAKQY
What is the function of this protein?
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
What are the official names of this protein?
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, THcHDO hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: Y858_METJA
Sequence: MNDKNVEFVATLISILTVKEALNSEMENFVKVRAAIDKRELKDDDKVAIFNINSTTSYQVFFIDKDTNIEELKEEFKKMNVRINYDSEQVLKRYIERLRIQNNSKPISNNNKQ
What are the official names of this protein?
Uncharacterized protein MJ0858.
Protein: DEOC_META1
Sequence: MKYNKLVDHTLLAPQATVHDIDKLIDEAIKYDFKSVCIAPTWIKHAKEKLAKSDVLVCTVIGFPLGSNATSVKVYETKIAIAHGADEIDMVINIGRFKNKEYEFVLNEIKAIKEECGSKTLKVIVETALLTNEEIAKVTEIVMQSGAEFIKTSTGFSYRGASFEDVEIMKRVAQDKLLIKASGGIKVGDDAIKMVELGANRLGMSKSIQIMEDLEKK
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.