PharMolix/UniProtQA huggingface dataset:
Protein: ARNA_PSEA8
Sequence: MTSKAVVFAYHDIGCTGIEALLNAGYEIAAVFTHADDPRENTFYASVARLCAERGIPLHAPEDVNHPLWLERIRQLRPDFLFSFYYRRLLGAELLACAARGAYNLHGSLLPRYRGRAPANWVLVNGETQTGVTLHRMIERADAGPILAQQAVAIDPEDTALSLHGKLRKAAGALLRDSLPLLALGVLPEVEQDESQASHFGRRTPADGLLDWHRPARQLYDLVRAVTQPYPGAFCQVGEQKLIVWSAEVVAGNHGREPGSVLSCDPLRIACGEDSLVLRFGQRGERGLYLAGTQLATELGLVEGARLRGAASGPQRRTRVLILGVNGFIGNHLSERLLRDGRYEVHGMDIGSDAIERLKADPHFHFVEGDIGIHSEWLEYHVKKCDVILPLVAIATPIEYTRNPLRVFELDFEENLRIVRYCVKYGKRVVFPSTSEVYGMCQDPDFDEDRSNLVVGPINKQRWIYSVSKQLLDRVIWAYGQQGLRFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCFTDVDDGIEALARIIDNRDGRCDGQIVNIGNPDNEASIRQLGEELLRQFEAHPLRAQFPPFAGFREVESRSFYGDGYQDVAHRKPSIDNARRLLDWQPTIELRETIGKTLDFFLHEALREREAQA
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: RRF_OCEIH
Sequence: MSASELKEMEQKMEQAVQALSKNLASVRAGRANPSILDSVFVDYYGASTPLNQLASVGAPEARLLTITPYDKSAIGDIEKAIQKADLGLSPSSDGNIIRINIPALTQERRKDLVKVVGKYSEEAKVQIRNIRRDTNDQLKKMEKNGDLTEDDLRGFQDDVQTSTNDYINKIDQLAKNKENEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_MYCTU
Sequence: MSTETRVNERIRVPEVRLIGPGGEQVGIVRIEDALRVAADADLDLVEVAPNARPPVCKIMDYGKYKYEAAQKARESRRNQQQTVVKEQKLRPKIDDHDYETKKGHVVRFLEAGSKVKVTIMFRGREQSRPELGYRLLQRLGADVADYGFIETSAKQDGRNMTMVLAPHRGAKTRARARHPGEPAGGPPPKPTAGDSKAAPN
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_MYCTA
Sequence: MAISFRPTADLVDDIGPDVRSCDLQFRQFGGRSQFAGPISTVRCFQDNALLKSVLSQPSAGGVLVIDGAGSLHTALVGDVIAELARSTGWTGLIVHGAVRDAAALRGIDIGIKALGTNPRKSTKTGAGERDVEITLGGVTFVPGDIAYSDDDGIIVV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: MURC_BARHE
Sequence: MKMPLNIGLIHFVGIGGIGMSGIAEVFHNLGYKVQGSDQIDNANVKRLQDKGIQVHVGHHAENLGDAEFVVLSTAIKKTNPEYIAAKERHLPLVKRAEMLAELMRFRRAIAVGGTHGKTTTTSMIAALLDAGSFDPMVINGGIINAYGTNARMGEGDWMVVEADESDGTFLKLPADIAVVTNIDREHLDHYGSFAAVRDAFRQFVENVPFYGFAVLCIDHPEVQSLASRIDDRWVITYGANPQADIRFLNLSMDGQKTYFDVFMRSRKTGRETELKNLVLPMSGQHNVSNATAAIAIAHELGISNESIKKGLAGFGGVKRRFTQIGSWRGVEIFDDYGHHPVEIKAVLCAARESAKGRVIAIAQPHRYSRLYHLFDDFAACFNDADIVLIAPVYAAGEEPITGFGARELVEHIQMAGHRDVRLIDCLEDVVSIVSTFSKSGDYVVFLGAGNITQWACALPNQLAVFDNNDKFSAD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPB1_CRYNJ
Sequence: MGKHDKKTGKGRLDKFYRLAKEQGYRARSAFKLVHLNRKYDLLSKARCCIDLCAAPGGWLQVAEKYMPKGSLIIGVDLNAIKPLPHVTTFVADITTPHCRQTLRQHMHDWKADLVLHDGAPNVGSAWVQDAFTQNELVLQSLKLATEFLAKGGSFVTKVFRSQDYNSLLWVFGQLFKSVEATKPPSSRNVSAEIFVVCRDFIAPKHIDPKFLDPKHVFKDIASLPTSITEPTDTSIAPTSSSTASAAAAAARLAANSHAHSNVYAPEKKRRHREGYAEGDYTLHHTASAEEFVRGQDPVLLLGNMNKIEFRNETEKGWLKSRHTTPDIIANFEDLKVLGKGDFKALMKWRLAIRLEIGLDVKADKTQDATEEVVVEPMDEEEQITEELQKLQQAKLAKTKRERKRANEKKARELLKLQLNMTVPDDLDQNDLALQGEEEIFDLEEGENEARRRGKNGGLATLVDDGEGMDLASESEEEEDEDEEDDEVLDSDEERERKTAALEGELDGLYDSYVERKKERDAKWKVKQDRLKDKNFDAWHGIQEKSDEEGSDDDDGQDDDEEGGWDVIAQKKAKYGEGDSSDSDSDAEPETEVPKKIKKVSFEKPARSEKSSGLMTSLREPELRAQRSKQAQLWFDQPVFKEVGDLAALDGDDEEEEEEDESEEEESDDEDVDMEDASESSSTLEGDDDFEIVPQAPEDDGPEWDVDDEDQDEVKKKVIQDKGLLTAEAVSLATALVNRKTTADKLIDQGFNRLSAHNKDGLPTWFLDDESQFYKPNIPITKEAVDALRARQRALDARPIKKVAEAKGRKKMKAVARMEKAKKKADGVMESEEMGDGEKARQVRRMLARAAKGKEKAKEKKIVVAKGVNKGVKGRPTGVKGKYKIVDARMRKEVRALKRIKKAGSKRR
What is the function of this protein?
Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
AdoMet-dependent rRNA methyltransferase SPB1, 2'-O-ribose RNA methyltransferase, S-adenosyl-L-methionine-dependent methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YGFX_SERS3
Sequence: MVQWQCNLRVSWRMQLFSLLAHGLLVLLILLAPWPDGYMSVWLGLVTLVMFGFIRSQRNIKSRHGEIVLYNENHLRWQHREWQITKRPWVLKNGILLSLRTTEGKGPRRRSLWLASDSMRNEEWRHLCHLLLQHKNWQSDRLM
What is the function of this protein?
Required for production of prodigiosin antibiotic (Pig); overproduction in ygfX, sdhE or double sdhE-ygfX deletion mutants leads to nearly 10-fold increased synthesis of Pig (PubMed:22474332, PubMed:23657679).  Overexpressing cells have somewhat altered cell length depending on growth phase (PubMed:23657679).  Does not function as a toxin; overexpression in the presence or absence of sdhE (the putative antitoxin) has no effect on growth rate (PubMed:23657679).
What are the official names of this protein?
Inner membrane protein YgfX.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUTC_CROTZ
Sequence: MPKQVIIPPGASTPIAPFVPGTLADGVVYVSGTLPFDKANNVVYPGDPKAQTRHVLETIRHVIETAGGTMEDVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPEALVEIATVAHIGPSGGA
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: ATPB_THAPS
Sequence: MVETTNKGYVCQIIGPVLDIEFPGGKLPPIYSAIKIETADGIGNIVEVQQLLGDNKVRAVSMRSTDGLKRGVEAVDLGAPITVPVGVPTLGRIFNVIGEPVDEQGDVVVDQTLPIHRDAPAFTELETKPSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYEEMKESGVINSSNFAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGALQERITSTTQGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRNLAAKGIYPAVDPLDSTSTMLQPGIVSEVHYETAETVKETLQRYKELQDIIAILGIDELSEEDRLVVARARKVERFLSQPFFVAEIFTGSPGKYVSLEETIKGFTMILNGELDDLPEQSFYLVGNIDEAIAKAETLK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RPC3_CANAL
Sequence: MDEVQMETARIQSPKSYLYTTLATTHLGEIASCIISILISNGRLTAREISNRTKIPTKNIKSALVSLIQLNCIYYWQEEKDRKFYYSLKETGLLLFVYSGDIINHIKRQYGEDEAEIIQNILIHGHVKIEDYLTQFNHDKSMKIDQENKFLKLFNDNWLIKLQDYHFHSLDDIWHKIFEECLKDTPRSSVTSEIKRVAEAQAKAKVKLNTLLESGTTGGGDIFTEVNGMKKLKPDLVVTFNLSRFQKHLRTNAFVNMVRSKIGVLTAIVYDAALRYIENKSPPMDYPLLDIPGLINDPKDVKEYILSIENKLVNEKKITFSARDIQRLLPKDIDFKNSVITPTFAKPKRPLENGSSPTLKKIKLEDGIASSTSTSTSTSSSTSSNGTSIDLNTLEQHLKLLLNGTNTAFVNEISPGNYTIPFSHLTNILKQNNFEALVKATLGDYAFRILRCVKSMKLCDEKSICNGALLKEKTVRSELYHLIKANIIEIQEVPRSADRAASKTFYLFRHKSNSNFNYLKNCLIYDMAEILNRIQDFKLEHKILLEKYKLVEGQEDQYLLDRELKLLNDLQLREIKNLVKFQRIKSLYSLYSLVD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DRS7_PHYTS
Sequence: ALWKDVLKKIGTVALHAGKAALGAVADTISQ
What is the function of this protein?
Antimicrobial peptide, active against the Gram-positive bacterium S. aureus, and the Gram-negative bacteria E. coli and P. aeruginosa.  Has hemolytic activity at 286 uM.
What are the official names of this protein?
Dermaseptin-TA1, DRS-TA1, Dermaseptin-7, DStar 07.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SMIM8_HUMAN
Sequence: MSSAPEPPTFKKEPPKEKEFQSPGLRGVRTTTLFRAVNPELFIKPNKPVMAFGLVTLSLCVAYIGYLHAIQENKKDLYEAIDSEGHSYMRRKTSKWD
What are the official names of this protein?
Small integral membrane protein 8.
What is the protein family that this protein belongs to?
Belongs to the SMIM8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL34_NITMU
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTAGGAAVIRARRAKGRVRLGVQ
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: DHAS_MYCSM
Sequence: MVNIGVVGATGQGRQVMRNLLEQRNFPATSVRFFASPRSEGKKLTFRGQEIEVENAETADPSGLDIALFSAGATMSRVQAPRFAEAGVIVVDNSSAFRKDPDVPLVVSEVNFDRDVRGKKLAKGIIANPNCTTMAAMPVLKPLHEEAGLQRLIVSSYQAVSGSGIAGVEELAGQARPVIDGVEQLVHDGSALQYPAPNKYVAPIAFNIVPLAGNYVDDGSGETDEDQKLRNESRKILGIPELLVSGTCVRVPVFSGHSLSINAEFSQPISVERTKELLSAAAGVKLVDVPTPLAAAGIDDCLVGRIRQDPGVPDGRGLALFVSGDNLRKGAALNTIQIAELLAADL
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: LRC10_HUMAN
Sequence: MGNTIRALVAFIPADRCQNYVVRDLREMPLDKMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALPQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNALRLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFPSLAHLSSLKLVIYDHNPCRNAPKVAKGVRRVGRWAEETPEPDPRKARRYALVREESQELQAPVPLLPPTNS
What is the function of this protein?
May play important roles in cardiac development and/or cardiac function.
What are the official names of this protein?
Leucine-rich repeat-containing protein 10.
What are the subcellular locations of this protein?
Nucleus.
Protein: IPK2_ORYSI
Sequence: MASDLRPPEHQVAGHRASADKLGPLVDGEGLFYKPLQAGERGEHEAAFYAAFTAHPAVPPRVRGAFFPRFHGTRFLPAPASPGGAPYPHIVLDDLLAGLPSPCVADVKIGACTWPPRSPDPYVAKCLAKDRETTSALLGFRVSGVRVVDARGGAVWRPDRSELKGIDAAGVRRVLRRYVSTGGGDGLDCALAAAVYGGEGGVLAQLRELKAWFEEQTLYHFYSASILFGYDANAAAAAAPGGGSGGVRVKLVDFAHVDDGDGVIDHNFLGGLCSLIKFIGDIVAEVTEKASSDHS
What is the function of this protein?
Inositol phosphate kinase with a broad substrate specificity.  Phosphorylates inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), inositol 1,4,5,6-tetrakisphosphate (Ins(1,4,5,6)P4), inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4), inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4) and inositol 1,2,3,4,6-pentakisphosphate (Ins(1,2,3,4,6)P5) but not inositol 1,4-bisphosphate (Ins(1,4)P2), inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), inositol 1,2,6-trisphosphate (Ins(1,2,6)P3), inositol 3,4,5,6-tetrakisphosphate (Ins(3,4,5,6)P4), inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5), inositol 1,2,4,5,6-pentakisphosphate (Ins(1,2,4,5,6)P5) or inositol hexakisphosphate (InsP6).  Regulates pollen and root development probably through the regulation of InsP3-mediated calcium accumulation.
What are the official names of this protein?
Inositol polyphosphate multikinase IPK2, OsIPK2, Inositol polyphosphate 6-/3-/5-kinase.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
Protein: Y197A_SYNY3
Sequence: MISIDLTLKYSPMPVSVQRKEKDGAEALYQTIVTAMQGDRPQVLELTCEKQTEKKVAIMSDQISAVIVSEKDGAASAGKVPGFAALGQIVNQG
What are the official names of this protein?
UPF0367 protein ssl1972.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: MUTS_JANMA
Sequence: MKTIKPQTPEGNEKHTPMMQQYLRIKAEYPTTLVFYRMGDFYELFFDDAEKASRLLGITLTQRGASNGNPIKMAGVPFHAVDQYLSKLVKLGESIAICEQIGDPATSKGPVERKVLRVITPGTLTDSDLLPEKSEQPLLALYSTTQRKTATIGLAWLSMASGVLKLMEFATDAQNADVRLKHELERIAPAEILLPGSVNDLFSEFSLAKNTTVPDWHFDIAHGTKALYEQLNVGTLTGFGAENLSAAIGAAGALLRYAQSTQGKGLQHVRTLTVETENEFIGLDAATRRNLELTETIRGQDANAATLFSLLDHCRTAMGSRLLRHWLHHARRDQSVAMARHAAINALMRADACSGLASTLASVPDVERITTRIALLSARPRDLAGMRGGLQQLPSLRAYVSMCNKDADAPLLKTIHDALATPSDCLDLVERAIAMEPAAMVRDGGVIARGFDAELDELRGLSENAGQFLIDLETRERARTGINNLRVEYNKVHGFYIEVTHGQTDKVPDDYRRRQTLKNAERYITPELKAFEDKALSAQERALAREKYLYEQVLQQMTQHIATLQNIAHALAQLDTLVALAEHALRHNWCAPQLVSEPTITIEQGRHPVVENHIERFIANDCLLSSECKLLLITGPNMGGKSTYMRQVALITLLAYVGSFVPASSAVIGPIDRIFTRIGAADDLAGGRSTFMVEMTESAAILNGATENSLVLMDEVGRGTSTFDGLALAWAIAKHLIDNTKSFTLFATHYFELTQLPEIHPTAANVHLSAVEHKDSIVFLHAVQAGPASQSYGLQVAQLAGVPQPVIRAARKHLALLEANSMQATPQFDLFAGGGSPTTVESAAEPQQASAVDEAIAAINPDALSPREALDALYRLKELSNQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: ZMYM5_MACFA
Sequence: MDKCSVGGLELTEQTPALLGNMAMATSLMDIGDSFGHPACPLVSRSRNSPVEDDDDVVFIESIQPPSVSAPAIADQRNFILASSKNEKPQGNYSVIPPPSRDLASQKGNISETIVIDDEEDIETNGGAEKNSSCFIEWGLPGTKNKTKDLDFSTSSLSRSKTKTGVRPFNPGRMNVAGDLFQNGEFATHHSPDSWISQSASFPRNQKQPGVDSLSPVALLRKQNFQPTAQQQLTNPAKITCANCKKPLQKGQTAYQRKGSAHLFCCTTCLSSFSHKRTQNTRSVICKKFASTKKADVVLPVESSRSFQEFCSTSCVSPCENNRNLKKGVFNKSRCTICSKLAEIRHEVSVNNVTHKLCSNHCFNKYRLANGLIMNCCEHCGEYMPSKSTGNNILVIGGQQKRFCCQSCINEYKQMMETKSKKLTASENRKRNAVREENEKQFCGLSSTLLKKIDGITEKKEKTSELHLSVECGTDTLLIKENVNLPPSSASAIADTFQEQLEEKNFEDSIVPVVLSADPGTWPRILNIKQRDTLVENVPPQVRNFNFPKDNTGRKFSETYYTRILPNGEKTTRSWLLYSTSKDSVFCLYCRLFGEGKNQLKNENGCKDWQHLSHILSKHEESEMHINNSVKYSKLKSDLKKNKAIDAAERRLYENEKNDGALLLYT
What is the function of this protein?
Functions as a transcriptional regulator.
What are the official names of this protein?
Zinc finger MYM-type protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSA_SULIA
Sequence: MAFGPAAMGYDRAITIFSPDGSLYQVDYAFEAVKKGWTAIGIKSKSGVVIASEKRKAQSLLDVDSIEKVFLIDDHVGCSFAGLASDGRVLIDYARNIALQHRLIYDEPVSIDYLTKSVADVKQMYTQHGGVRPFGVALVIAGIDKSVPKLYMTEPSGQYMPYQAVAIGQGYYTATEFLEKNYKEDLTIEDTILLALKALSATLKPNEKLTPNTVEIGYASTQTGLFLKMTSEDKNMYLQKL
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PsmA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_RICFE
Sequence: MSEIEEKFNESSYGADSIKVLKGLEAVRKRPGMYIGDVGDGSGLHHMIYEVVDNAIDESLAGYCDLVRVTLNKNGSVTVSDNGRGIPVEIHQEEGISAAEVIMTQLHAGGKFDQNSYKVSGGLHGVGVSVVNALSEWLELRIWRNNKEYLIRFNNGITEAPLAVVNEDINKKGTEVTFFPSVETFTNIEFDFGTIEHRLRELAFLNSGVKILLVDNRFEEAKEVEFYYTGGIEAYVKYIDRAKHAVHPCIVVNTENTESGISLELAMHWNDSYHENILCFTNNIRQRDGGTHLSAFKSAITRVITSYLDTTGLNKKSKNDFSGEDTREGLCCVLSVKVPDPKFSSQTKDKLVSSEVRPVVENAVYTKVLEWFEEHPAESKAIIAKIMEAANAREAARKARELTRRKSALEVSNLPGKLADCHAKDPAISELFIVEGDSAGGTAKQGRDSKIQAILPLRGKILNVERARFDKMLGSDQIGTLITALGTGVDNREFSLEKLRYHKVIIMTDADVDGSHIRTLLLTFFYRHMPELINKGYLYIAQPPLYKVKKGAAEFYLKNEQALQDYLIKSTINDATLTLDGKEQLVGDNLEELINKVVKFNGLLDHASKKFNRSITEILAINDLLNNKIFELESDSRLQKALDVLNSLEESPDKTNWEVLKHENKVEFFRFSRGLKESKILLKEQLESFEFVQISKLALTIFDIFDKQLKLIVKSQEFGILTASQLLNAIIECGKRGISIQRFKGLGEMNSNQLWETTLDPAKRTLLQVRVAEVDEAEGIFSTLMGDVVEPRRLFIQANALNVVNLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_PSEF5
Sequence: MAVQQNKKSRSARDMRRSHDALEASTLSVEKTTGEVHLRHHVSPEGVYRGRKVIDKGADE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GCSPB_PYRHO
Sequence: MYRQARWDEPLIFELSRPGRVGYTLPKPIEDVKVEIPEKLKRKTPLELPEVSEPEVVKHYTRLSEMNYGVDSGIYPLGSCTMKYNPKINEEIANHPKVAFIHPYQDERTVQGALKIMWELEQWLKEITGMDRFTLQPAAGANGEFTGVMIIKAYHLDRGDTQRTEILVPDSAHGTNPASASMAGFKVVEIPSNENGTVDLEALENAVSERTAGLMLTNPNTLGIFEDEIEEIAKIVHKVGGLLYYDGANLNGILGKVRPGDMGFDIVHLNLHKTFSTPHGGGGPGAGPVGVKEFLKDYLPVPLVSYDEENDRYYLDYNVPKSIGKVKELFGNFAVLVKALTYLKIMGKEGLREVSEVAVLNANYLARKLKGTRGYELPHKELRKHEVVFSAEPMKKETGVRTLDVAKRLLDFGLHAPTIYFPLIVHEALMIEPTESVSKEELDAYVEALKKISEEAYTNPEIVKSAPHNTAVRRVDDVLAAKKPVITWKMYKELKEKGEIDY
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: THIG_ACIAD
Sequence: MQDSPLIIGSRQFQSRLLVGTGKYKDLNETDLAIQASGAEIVTVAIRRVNIGQHADQPNLLSVIPPEKYTILPNTAGCFDADSAIRTCMLARELLDGHNLVKLEVLGDQDTLYPNITETLKAARTLIDDGFEIMVYTSDDPIVAKELESMGCVAIMPLGSLIGSGLGILNPHTISIIKENAKVPVLVDAGVGTASDAAIAMELGCDGVLMNTAIAAAQHPVLMASAMKKAIEAGREAFLAGRMPRKRMANASSPETGYFFK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_ROSDO
Sequence: MDASTVSRETMHALQMYHDLLLKWNARINLISKSSIEDVWSRHIWDSAQVVDCVAKAKTWVDLGSGGGMPGIVVAIFAKNIDPDRRVILVESDQRKAAFLRTVIRELSLNARVIVERIEDVAPLRADVVSARALADLSVLLSFAQRHLSAQGTALFMKGQSWEKEVSSAQETWSFDLKAHRSKTSPAAAILEIKEIQRV
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_ECOBW
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ISIK_HELPO
Sequence: QGRPSFCNLPAETGPCKASFRQYYYNSKSGGCQQFIYGGCRGNQNRFDTTQQCQGVCV
What is the function of this protein?
This is one of several isoinhibitors of broad specificity that are secreted into the mucus of the snail.
What are the official names of this protein?
Isoinhibitor K.
What are the subcellular locations of this protein?
Secreted.
Protein: ENO_CHRSD
Sequence: MAEIKDIHALEVLDSRGNPTVQADVVLASGVRGTACAPSGASTGSREALELRDGDTSRYLGKGVLKAVEAVNGRIRDALVGKDALDQRALDAAMLELDGTDNKAGLGANAILAVSLAAAKAAAIEKGVPLYAHIADLYGQSGQFRMPVPMMNILNGGEHADNNVDIQEFMIQPVGAPSFREALRMGAEIFHALKKVLAARGLSTSVGDEGGFAPNLASNAEALAVIQQAVEKAGYVLGKDVTLALDCASSEFYQDGQYNLSGEGKSYDAAGFVDYLAALCDQYPIVSIEDGMDESDWAGWKALTEKLGDKVQLVGDDLFVTNTRILKRGIDEHIGNSILIKFNQIGSLSETLDAIKMAQDAGFTAVISHRSGETEDTTIADLAVGTSAGQIKTGSLCRSDRVAKYNRLLVIEQELEGQAVYPGLAAIKGQG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.