PharMolix/UniProtQA huggingface dataset:
Protein: NUOD_JANSC
Sequence: MMDGDIRVNTYDDGSTDFQTGEQKIRNFNLNFGPQHPAAHGVLRLVLELDGEICERCDPHIGLLHRGTEKLMESRTYLQNLPYFDRLDYVGTMNQEHAWCLAIERMTGTDVPRRAQLIRVLYCEIGRILNHLLNVTTQALDVGALTPPLWGFEEREKLMIFYERASGARLHAAYFRPGGVHQDLPPELIEDIDTWAHEFPQMLDDIDGLLSENRIFKQRNVDIGVVTEEDIQNWGFSGVMVRGSGFAWDLRRAQPYECYDEFEFQIPVGKNGDCYDRYLCRMAEMRESTKIIHQACEKLRNEPGEIMSRGKMSPPSRGDMKTSMEALIHHFKLYTEGFHVPEGEIYACVEAPKGEFGVFLVADGTNKPYRAKLRAPGFAHLQAMDYLCKGHQLADVSAVLGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Z354B_MOUSE
Sequence: MAPEQREGKSQVSVTFEDVAVLFTRDEWKKLVPSQRSLYREVMLENYSNLASLGFPFTKPKMISVLQQGEEPWKSEKESHGCSPLGCHGSLQTTKSTQTKESLFQELKRKQLKRDEAWDFTSGKSCRPDNSFRTQDTNESLEIISINHTKILTIDKSRKNFKFGPSVGLKSIGKQKIAGEKTQRNSLEENSTLLSQPKLKTVEKRYKCSTCEKAFIHNSSLRKHLKNHTGERLFQCKDCLKAFSQSSALIQHQRTHTGEKPYICKECGKAFSHSASLCKHLRTHTLEKSYTCKECGKSFSRRSGLFLHQKIHARENPHKYNPGRKASTSLSGCQRIHSRKKTYLCNECGNTFKSSSSLRYHQRIHTGEKPFKCSECGRAFSQSASLIQHERIHTGEKPYRCSECGKGFTSISRLNRHRIIHTGEKFYNCNECGKALSSHSTLIIHERIHTGEKPCKCKVCGKAFRQSSALIQHQRMHTGERPYKCNECGKTFRCNSSLSNHQRTHTGEKPYRCQECGMSFGQSAALIQHRRIHTGEKPFKCNTCGKSFRQSSSLIAHQRIHTGEKPYECSACGKLFSQRSSLTNHYRIHIEEDALNIDLHE
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 354B, Kidney, ischemia, and developmentally-regulated protein 2.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FIB36_BPT4
Sequence: MADLKVGSTTGGSVIWHQGNFPLNPAGDDVLYKSFKIYSEYNKPQAADNDFVSKANGGTYASKVTFNAGIQVPYAPNIMSPCGIYGGNGDGATFDKANIDIVSWYGVGFKSSFGSTGRTVVINTRNGDINTKGVVSAAGQVRSGAAAPIAANDLTRKDYVDGAINTVTANANSRVLRSGDTMTGNLTAPNFFSQNPASQPSHVPRFDQIVIKDSVQDFGYY
What is the function of this protein?
Structural component of the distal-half of the long-tail fiber.  The long-tail fiber of T4 is about 1600 Angstroms long with a kink in the middle that divides the fiber into proximal and distal halves.  The thin tip of the distal half-fiber interacts with the bacterial lipopolysaccharide receptor and specifies the host range of the phage.
What are the official names of this protein?
Long-tail fiber protein gp36, Gene product 36, gp36.
What is the protein family that this protein belongs to?
Belongs to the tevenvirinae tail fiber protein p36 family.
What are the subcellular locations of this protein?
Virion.
Protein: ATPA_LEPBL
Sequence: MKIKTDEITSVLKQEILNYKKDLGVDEVGTVLEIGDGIARVYGLKNVMSGEMVEFQNGIFGQAFNLEDNSVGVVVYGDYLAIQEGFTVKRTSRILEVPVGPELLGRVVNPLGEPLDGKGPINAKLTRPVESPAPGIAMRQPVGEPMQTGIKAIDAMIPIGRGQRELIIGDRGTGKTSIALDTIINQKGTGVICVYVAIGQKASTVASTVEMLRNKGALEYTIVVSATAAEPAPLQYIAPYSGCSMAEYFMYNEKKATLVVYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLDDKYGAGSLTALPIIETQEGEVSAYIPTNVISITDGQIYLQSNLFASGNRPAVDVGISVSRVGSAAQIKAMKQVAGKMKLELAQFRDLEAFAQLGTELDPATQAQLDRGNRIVQMLKQPVSSPFPVEEQVVEIFAVTRGFMDKIPVPKVQQYGKFLLTRIKEQHSEVLEAIRKEKKISDEEKLGEVLSAIAEEFLRKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PGK_CORDI
Sequence: MAIKTLKDLLAEGVEGRHVLVRSDFNVPLNDDREITDAGRITASLPTIKALVDNGARVILMAHLGRPKGEVNEKFSLAPVAEALSEALGQYVALAGDVVGEDAHERANGLNDGDVLLLENVRFDPRETSKEEAERGEFADQLVALTAENGAFVSDGFGVVHRAQASVFDVAQRLPHYAGTLVEKELEVLGNKVASAPERPYAVILGGAKVSDKLGVIEALATKADKLIIGGGMCYTFLAAKGINVQKSLLQEEQINKCKELLEAYADKIVLPVDLVAAAEFASDAENKIVAIDEIPEGWMSLDVGPKTVEKFAEVLATSKTVFWNGPMGVFEFENFSAGTRGVAEAIIAATANGAFSVVGGGDSAAAVRLLGLDEDGFSHISTGGGASLELLEGKNLPGVSVLES
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXH_AROAE
Sequence: MSALFISDLHLCEQRPVTLRAFFAFLQGPARSVQALYILGDLFEYWAGDDDATPLDNAVSDALAALAETGTSLFFLPGNRDFLLGESFARRARLRILPDPTLIDFDNEGVLLSHGDILCTDDEHYQSFRRLVRDPAWQLAFLERPLAQRKQVIEGLRFQSETAKQEKASDIMDVNAFAVETLLREHGYPTLIHGHTHRPAHHVHVVDGRSCERWVLADWHDDAPYLRWDGAGPPVALRFGAKLGT
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL9_BLOPB
Sequence: MKIILLDNIDKLGNKGSEVVVRSGYARNFLIPKSKAMLATKKNIEIFKAQQLELQSKAIEAQTQAEFCAKTINRLGSITIKAKSGVEGKLFGSIGSRDIATAITAASGFNISKSQIRLPNHDVLRTIGTYSINIHIYNDIFSKINVIILDEIV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: HN131_CYRHA
Sequence: ECKWYLGTCSKDGDCCKHLQCHSNYE
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Hainantoxin F1-31.97, Peptide F1-31.97.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 17 (Hntx-9) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TU92_GEMSO
Sequence: MKVYCLLLVLLVGLVSQAHGQLDKKCQMVCTMDYRPVCGSDGRTYPNKCTLTSTACMSQRSITVFHDGEC
What is the function of this protein?
Acts as a neurotoxin by inhibiting an ion channel (By similarity).  May also act as a serine protease inhibitor, since it possess the kazal serine protease inhibitor signature.
What are the official names of this protein?
Turripeptide Gsg9.2.
What is the protein family that this protein belongs to?
Belongs to the conopeptide P-like superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_TRIV2
Sequence: MNNIFSKLRDFVGLNEQVEYEYYEEEADTDNYQNLYQQENPQPAPAEAAPNNRRWREPMTTMGDDVATGTKSAMGNVIGMPGAINGISEVLVLEPRTFEEMPQAIQALRERKSVVLNLTIMDPDQAQRAVDFVAGGTYALDGHQERIGESIFLFTPSCVQVSTQGGVIHEVPQPPARPARPASTNPPAWGNETNRMAQ
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RYBPA_DANRE
Sequence: MGDKKSPSRPKRQAKPSADNGFWDCSVCTFKNSAEAFKCSICDVRKGTSTRKPRINSQLVAQQVAQQYAAPPPAKKERRERTDRDLPDDDHFDMDNSDSDRLSSLHPDSDHPERLGLEGGQLDRGHSLKERRQERVLDKPQALDTDRRPERAGLTPDLLQQQQPQPQQHPQQPQQPQQHSQQQPQQHPPQQHNRIDREHTDRAMLEKLQPLREHMEKDHPHTAGSGMQPAERMGAEREELKKGKIERAMMEKHKERHKSLTPSKKPTPKKMKPKLIQKSPAGESNGMKPGKSVTKNNKSVISRPKLKNVDRSSAQQLAITVGNVTVIITDFKEKTRSSSTSSSTVTSSAGSEQQHLSSSSESTDKGSSRASTPRRDHSSGHNETL
What is the function of this protein?
May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1.
What are the official names of this protein?
RING1 and YY1-binding protein A, Death effector domain-associated factor A, DED-associated factor A.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Primarily found in the nucleus.
Protein: XYLA_YERE8
Sequence: MQSYFDELEQVRYEGSQNTNPLAFHHYNPDEIILGKRMADHLRFAACYWHTFCWGGADMFGSNAFERPWQQSGDALALAKRKADVAFEFFHKLNVPYYCFHDVDVSPEGASLKEYLNNFAVMTDVLAEKQASSGVKLLWGTANCFTHPRYGAGAATNPDPEVFSWAATQVFTAMNATQKLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDPQLGWDTDQFPNSVEENALVMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAAKMIEDGQLDKQVAERYAGWSSDLGQQILKGKMSLEDLASYAEQHNLNPHHQSGHQELLENRVNRYIFG
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CITA_KLEPN
Sequence: MSIYPMYTRKITHWFARRSFQNRIFLLILFTSTIVMLAMSWYLTDITEERLHYQVGQRALIQAMQISAMPELVEAVQKRDLARIKALIDPMRSFSDATYITVGDASGQRLYHVNPDEIGKSMEGGDSDEALINAKSYVSVRKGSLGSSLRGKSPIQDATGKVIGIVSVGYTIEQLENWLSLQISSLLIPMAIMLLLLLFCARRFSLHIKKQMLNMEPQQLSQLLIQQSVLFESVFEGLIAIDSDYKITAINQTARRLLNLSQPEPTLIGKRISSVISQEVFFYDAPQTNKKDEIVTFNQIKVIASRMAVILNNEPQGWVISFRSKDDINTLSLQLSQVQQYADNLRAVQHEHRNLISTIAGLLFLKRYNQALELIQQQSESHQKVIDFIARNFQDNHLAGLLIGKYYRAKELGLELIFDPACFVDRLPTALSHNEWISIVGNLLDNAYNASLRQPQGSKQIECLINSDGQEVIIEIADQGCGIDEALRDRIFERGVTSSASKDHGIGLWLVRSYVEQAGGSIVVENNIPFGTIFTLYIPLTRDEHHG
What is the function of this protein?
Member of the two-component regulatory system CitA/CitB.  Probably activates CitB by phosphorylation.  The periplasmic domain binds H-citrate(2-), which is essential for induction of the citrate-fermentation genes.
What are the official names of this protein?
Sensor histidine kinase CitA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PEPT_ECO81
Sequence: MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAQRK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPK13_ORYSJ
Sequence: MEFFTEYGEASQYQIQEVVGKGSYGVVAAAVDTHTGERVAIKKINDVFEHVSDAIRILREIKVLRLLRHPDIVVIKHIMLPPTRREFRDIYVVFELMESDLHQVIEANHDLSPEHHRFFLYQLLCALKYIHSANVFHRDLKPKNILANSDCKLKICDFGLARVAFNDSPSTIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSIGCIFAEILTGRPLFPGRNVVHQLDLITDLLGTPSSETLSRIRNENARGYLTGMQRKHPIPFSHKFHNADPLALRLLERLLAFDPKDRPTAEEALADPYFRGISKLSREPSRLPVSKFEFEFERRKLTKDDVREMIYREILEYHPQMLQEYIRGGEQISFLYPSGVDRFKRQFAHLEENYSRGERSTPLRRQHASLPRERVCSSVDSNNQDSDNEERRAISSIARTMISPPRSQEKGKNRASAYPNGIINLNSNPKIYLKSASISASTCIIRGNKGPKENGISEDMEEVVYELSDNVTRMLS
What are the official names of this protein?
Mitogen-activated protein kinase 13, MAP kinase 13, Benzothiadiazole-induced MAP kinase 2, MAP kinase 2, OsBIMK2, OsBWMK2, OsMAPK2, OsMPK17-2, Wound- and blast-induced MAPK 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: ALF2_STAAW
Sequence: MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAPVILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKECQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKDIQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKIKEFGTSNRAK
What is the function of this protein?
Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
What are the official names of this protein?
Fructose-bisphosphate aldolase, FBP aldolase, FBPA, Fructose-1,6-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family.
Protein: DTPD_SALPC
Sequence: MNKQASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYDDNHAYELFSAYCSLVYVTPILGGYLADKVLGNRMAVMLGAFLMAIGHLVLGASEIAPTFLYLSLAIIVCGYGLFKSNISCLLGELYQPEDPRRDGGFSLLYAAGNIGSIVAPIACGYVQEEYSWAMGFALAAIGMLAGLVIFLCGNRHFTHTTGVNKAVLCARNYLLPNWGWLLILLVAAPLLITVLFWKEWSVYALIVATAISLVVLAKIYRQAQTAKQRKELGLIVTLTLFSMLFWAFAQQGGSSISLYIDRFVNRDILGYSVPTAMFQSVNAFAVMLCGVVLAWLVKESVSGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAAYGHSSMPLMVLGLAVMGFAELFIDPVAMSQITRIDIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQSAFDASGAVNYAINAYVDVFEQITWGALACVGVVLLIWLYQSFKFKSRALAVES
What is the function of this protein?
Probable proton-dependent permease that transports dipeptides.
What are the official names of this protein?
Dipeptide permease D.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS6_BORA1
Sequence: MTQTQGPTASALTRRIIPCLDVTAGRVVKGVNFVNLTDAGDPVEIARRYNEQGADELTFLDITATSDGRDLILPIIEQVASQVFIPLTVGGGVRQVSDVQRLLNAGADKISINSAAISNPELVRAAADYHGSQCIVVAIDARRVSSEGEAARWEVFTHGGRRATGLDAVAWARRMAAYGAGEILLTSMDRDGTKSGFDLELTRTVSDAVPVPVIASGGVGNLEHLAEGVTTGRASAVLAASIFHFGQHTVRECKAFMAQRGIDVRLD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXJ_SALTI
Sequence: MAELLLGVNIDHIATLRNARGTDYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTLHTRMNLEMAVTEEMLAIAVETRPHFCCLVPEKRQEVTTEGGLDVAGQRDKMRDACARLAAAGIQVSLFIDADERQINAAAEVGAPFIEIHTGCYANAETDAEQAKELARIASAATLAARLGLKVNAGHGLTYHNVKAIAALPEMHELNIGHAIIGRAVMTGLKEAVAEMKRLMLEARG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_PAVHV
Sequence: MELFRGVLQVSSNVLDCANDNWWCSLLDLDTSDWEPLTHTNRLMAIYLSSVASKLDFTGGPLAGCLYFFQVECNKFEEGYHIHVVIGGPGLNPRNLTVCVEGLFNNVLYHLVTENVKLKFLPGMTTKGKYFRDGEQFIENYLMKKIPLNVVWCVTNIDGYIDTCISATFRRGACHAKKPRITTAINDTSSDAGESSGTGAEVVPINGKGTKASIKFQTMVNWLCENRVFTEDKWKLVDFNQYTLLSSSHSGSFQIQSALKLAIYKATNLVPTSTFLLHTDFEQVMCIKDNKIVKLLLCQNYDPLLVGQHVLKWIDKKCGKKNTLWFYGPPSTGKTNLAMAIAKSVPVYGMVNWNNENFPFNDVAGKSLVVWDEGIIKSTIVEAAKAILGGQPTRVDQKMRGSVAVPGVPVVITSNGDITFVVSGNTTTTVHAKALKERMVKLNFTVRCSPDMGLLTEADVQQWLTWCNAQSWDHYENWAINYTFDFPGINADALHPDLQTTPIVTDTSISSSGGESSEELSESSFFNLITPGAWNTETPRSSTPIPGTSSGESFVGSSVSSEVVAASWEEAFYTPLADQFRELLVGVDYVWDGVRGLPVCCVQHINNSGGGLGLCPHCINVGAWYNGWKFREFTPDLVRCSCHVGASNPFSVLTCKKCAYLSGLQSFVDYE
What is the function of this protein?
Multifunctional protein essential for viral DNA replication, which cooperatively interacts with the viral DNA origin of replication and transactivates several promoters including the viral p6 promoter (PubMed:27809499, PubMed:24418564, PubMed:11853402).  Binds the origin of replication and performs an endonucleolytic nick within a conserved sequence in the viral genome, thereby initiating the rolling circle replication (RCR) (PubMed:27809499).  Participates in the transcriptional regulation the viral p6 promoter that regulates all viral transcripts and the cellular CDN1A or IL6 promoters (PubMed:8970971, PubMed:11853402).  Transactivates several host promoters some of which induce the S cell cycle phase for the production of host replicative proteins (PubMed:20890043, PubMed:15518826, PubMed:24049177).  Up-regulates the expression of host E2F4 and E2F5 and interacts with both these factors thereby inhibiting the host cell cycle G2/M transition (PubMed:20890043).  This arrest promotes apoptosis for viral release (PubMed:20890043, PubMed:9525624).
What are the official names of this protein?
Initiator protein NS1, NS1, NCVP1, Non-capsid protein NS-1, Non-structural protein 1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: NEF_SIVG1
Sequence: MGSSNSKRQQQGLLKLWRGLRGKPGADWVLLSDPLIGQSSTVQEECGKALKKSWGKGKMTPDGRRLQEGDTFDEWDDDEEEVGFPVQPRVPLRQMTYKLAVDFSHFLKSKGGLDGIYYSERREKILNLYALNEWGIIDDWQAYSPGPGIRYPRVFGFCFKLVPVDLHEEARNCERHCLMHPAQMGEDPDGIDHGEVLVWKFDPKLAVEYRPDMFKDMHEHAKR
What is the function of this protein?
Interferes with TCR signaling from the cell membrane.  Interacts with CD247/TCRZ (TCR zeta chain) and exert potent down-regulation of cell surface TCR/CD3 complexes (By similarity).
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: RBL_ALNIN
Sequence: MSPQTETKASVGFKAGVKDYKLTYHTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREAAKWSPELAAACEVWKEIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL24_YERPY
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNLALFNATTGKADRVGFRFEDGKKVRFFKSTSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TRM13_YEAST
Sequence: MLQDNNGPAVKRAKPSERLQCEYFMEKKKRRCGMTRSSQNLYCSEHLNLMKKAANSQVHNKNGSEAEKERERVPCPLDPNHTVWADQLKKHLKKCNKTKLSHLNDDKPYYEPGYNGENGLLSSSVKIDITAEHLVQSIELLYKVFEGESMDELPLRQLNNKLMSLKRFPQLPSNTKHAVQQSSLIENLVDAGAFERPESLNFIEFGCGRAEFSRYVSLYLLTQLTSLPAEHSGSNSNEFVLIDRATNRMKFDKKIKDDFSEIKSNSPSKPISCPSIKRIKIDIRDLKMDPILKSTPGDDIQYVCISKHLCGVATDLTLRCIGNSSILHGDDNNGCNPKLKAICIAMCCRHVCDYGDYVNRSYVTSLVEKYRAHGSILTYETFFRVLTKLCSWGTCGRKPGTAITDIVNVVESFEGAEPYTITIKERENIGLMARRVIDEGRLVYVKEKFTEFNAELIRYVESDVSLENVAMLVYKK
What is the function of this protein?
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
What are the official names of this protein?
tRNA:m(4)X modification enzyme TRM13, tRNA methylase 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TRM13 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATP8_CARAU
Sequence: MPQLNPGPWFAILVFSWLVFLTIIPTKILSHISPNEPTPVSAEKHKTESWDWPW
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: VATB2_TREPA
Sequence: MKGVWYRGLSSIDGPIVVAKRREGAFYGEITAIRDRFGALRTGRIIDLSQECCLIQVFGSTLGLSLDGACLEFLDVPMQLRVCEGLMGRVFDGLGRPIDGFPEVLSSQLRNVNGYPINPYARVYPRDFIQTGISAIDGMNTLIRGQKLPIFSGNGLAHNRLAAQIIRQAKILGTDEAFVMVFAGMGIKHDVARFFVSSFEETGVLSKVVMFLSLADAPSIERIITPRCALTAAEYLAFEKNKHVLVIFTDMTNYCEALREVSTTRGEVPGRKGYPGYLYSDLAELYERAGRVKGSSGSVTQIPILTMPNDDISHPIPDLTGYITEGQIVLQRDLSQRGLYPPIGCLPSLSRLMKDGIGEGMTRADHHAVSSQLFASYARVQSVRSLASIVGEEELPALDKCYLRFGDLFEQYFLTQDEHEDRSISQTLDIGWSLLSLLPRTELYRIDPKLIDQYLTASCSAVSDQLRKAIEEARTPVADA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type beta chain is a regulatory subunit (By similarity).
What are the official names of this protein?
V-type ATP synthase beta chain 2, V-ATPase subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: COBQ_NOVAD
Sequence: MLQGTGSDVGKSVLVAGLCRALVQRGLRVLPFKPQNMSNNAAVTSDGGEIGRAQALQAIACKVEPHTDMNPVLLKPQADRTSQLIVHGRVRGTLGAGNFRQARGALLGEVLASYNRLRRACDIVVVEGAGSPAEINLRAGDIANMGFARAAGVPVVLVGDIDRGGVIAAIVGTRTIIDPADTAMIQGFIINKFRGDPALFADGYAQIESLSGWRGFGVVPWLSAAARLPSEDAVVLESGKARAESRKLIACPILPRISNFDDLDPLKLEHGVDLHMVPPGQPIPAEAALIILPGSKSTIADLAALRAEGWDIDIFAHHRRGGLILGLCGGYQMLGKSIADPDGFEGSASAASGLGLLDVETTLHAHKALRPVSGLAMGAPFQGYEMHMGQTNGPDTEQPFAVFADGRRDGAINAGGTVFGSYVHGLLADAELRRALLSRMDVEAGGVDYGASVEAALDEIAAALEEHLDIDALVALAMAERPASVPAGDSA
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.