PharMolix/UniProtQA huggingface dataset:
Protein: PENC2_PENCI
Sequence: MKGFLGLALLPLLTAASPVSVESIHNGAAPIISSMNSQEIPDSYIVVFKKHVDTSAAAAHHSWVQDIHSAVNGRMELKKRGLFGFDTDAFLGVKHSFHVAGSLMGYAGHFHEDVIEQVRRHPDVDYIEKDSEVHHFDSPSVEKNAPWGLARISHRDSLSFGTFNKYLYAEDGGEGVDAYVIDTGTNTDHVDFEGRASWGKTIPQGDEDVDGNGHGTHCSGTIAGKKYGVAKKANVYAVKVLRSNGSGTMSDVVKGVEWAAEAHIKKSKAAKDGKAKGFKGSVANMSLGGGSSRTLDLAVNAAVDAGMHFAVAAGNDNADACNYSPAAAEKAVTVGASTLADERAYFSNYGKCTDIFAPGLNILSTWIGSKYAVNTISGTSMASPHIAGLLAYYVSLQPSDDSAFAVEKITPKKLKEALITVATSGALTDIPSDTPNLLAWNGGGSSNYTDIVAQGGY
What is the function of this protein?
Serine protease.
What are the official names of this protein?
Subtilisin-like serine protease Pen c 2, Vacuolar serine protease Pen c 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: SYR_MIMIV
Sequence: MQDNLIYLANCFLNEAIKTTLQNLNKVNIIDTPELYSFVKGINTDYQFNKSTKLANDCNLDKEKIVNELITQLKSNSFFENISSVELEQNKSVKINGKKTNTVIKQIMITLNISKLYLSNRINLLYKRILSGSSIYVPNTITKKIIVDYSSPNIAKEMHIGHLRSTIIGESICRVLEMCGHDVYRINHVGDWGTQFGMLIAYIKNNQIESYTISELMNIYKESRKLFESSIDFKNQSRLETVSLQNGNIESITIWQKIHKISMNSFHEIYSLLGINNLITKGESFYQDQMTELVNSLTSDNKITVENDMKLMFVEGISKPFILQKSDGGFTYDTSDLTALKYRLFIEKADHIIYVVDSSQQEHFSQMFQIAEKLDWIKNQQLQHIGFGLVLGSDGSKLKTRSGETIKLQDVIDNVVSHASNITRELIKQKNLDWNDDDILTISKKIAINCIKYSDLNNPRLNNYKFDINKMLNSKGNTAVYLMYGLARCKSILRKVPNNTVLNGDIIIENENSRNLLLHVLKYVEVIDQTVETMCPHYLCIYLYDLIGSLTKFYTTNRCLEYDNDNLIGYNANNLRIVNMVKIIISKIFELIGLEEIEQL
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
Protein: RL1_METHJ
Sequence: MVEKSVLIDALKKAKEQAPERKFTESVDMTINLKNIDMSQPKNRIDETILLPHGNGRVVKIAVLGSGDIVTQARESGVELIMGPEEIERLGGAPREARKIASEHQFFLAETQVMSLVGRWLGPRLGPRGRMPQPIPAGTDIRPIVERLRKSVKIRTKDKMSFSLKVGTTAMSEEEIAENIDAVLKRILSKLEMGDFQVRSVYIKTTMGPSVKVEL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: HOX27_ORYSJ
Sequence: MELGLSLGDAVTVADGGRLELVLGLGVGVGAGVRRGEEEERGRREDVVGAGRWAAMAAASPEPSVRLSLVSSLGLHWPSETGRSEAAARGFDVNRAPSVAAGAPGMEDDEEGPGAAPALSSSPNDSGGSFPLDLSGQGLRGHAEAAAQGGGGGGGGERSSSRASDDDEGASARKKLRLSKEQSAFLEESFKEHSTLNPKQKVALAKQLNLRPRQVEVWFQNRRARTKLKQTEVDCEYLKRCCETLTEENRRLHKELAELRALKTARPFYMHLPATTLSMCPSCERVASNPATASTSAPAAATSPAAAPTAAARTAVASPEPHRPSSFAALFAAPLGFPLTAAQPRPPPPASNCL
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX27, HD-ZIP protein HOX27, Homeodomain transcription factor HOX27, OsHox27.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class II subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y079_PERMH
Sequence: MAGHSKWHNIRHKKAKMDAKRGQMFTKIIREITVAARQGGGDPEFNPRLRIAIEKAKKANMPVENIERAIKRGTGELEGVSYEEVVYEGYGPEGVAIIVECLTDNRNRTTGEVRHIFTKHGGNLGSSGCVSFLFEEKGVILVPKDKYDEETVFEKAIEAGAEDVITDDEEFYEIRTEPKELYTVKENLEKEGIEIEKAELTRIPTTTVEINDEETATKLMKLLDALEDNDDVQKVYSNFEMSQQLMEKVS
What are the official names of this protein?
Probable transcriptional regulatory protein PERMA_0079.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_CERS5
Sequence: MSRYDPAATESRWQAAWDEAGVFTARHDPSRPKYYVLEMFPYPSGRIHMGHVRNYTMGDVVARQKAAAGYSVLHPMGWDAFGMPAENAAMERGGHPKDWTYGNIADMRAQMKPLGLSIDWSREFATCDPEYYGQQQAMFIDMLEAGLIYRKNAVVNWDPVDMTVLANEQVIDGKGWRSNAPVERRELTQWFFRISDYAGELLEALDRLKDWPEKVRLMQANWIGQSRGLQFAFSTVNAPEGFDRLEVYTTRPDTLLGASFAAISPDHPLAKHLERHDAGVAEFVAECRRVGTSEEALEKAEKKGFDTGIRVRHPFDTALELPVYIANFILMDYGTGAIFGCPAHDQRDFEFASKYGLPIPPVFVAEGTEEAPLTEAFVPMKSERVAYVRGFAGAEIQTGEEAVAAAIDFCESKGVGRGVTNYRLRDWGISRQRYWGCPIPVIHCETCGVVPEAKENLPVRLPDDVTFDVPGNPLDRHPTWRDCTCPKCGAKARRETDTMDTFVDSSWYYARFTAPRATTPTDPEEAEYWMNVDQYIGGIEHAILHLLYSRFFARAMQKTGHLPAKAIEPFNALFTQGMVTHEAYYSEEAKQEPVWQGMLEPGESPDTQMTVRHITYHFPEEVERTEDGAILKTTGQKLKVIPSTKMSKSKKNVVDPMNIISQFGADTARWFVMSDSPPERDVEWTASGAEAAFKHLGRVWRLADEIARAEGAPTAEDVALDRATAKAIAEVTQGIEGFAFNKAIAKLYEFTNTLSRSGAGAEAKRRAMRTMAQLMSPMVPHLAEEVWSMLGGEGLVAQAPWPKADPALLVDDMVTLPIQINGKRRAEVTVPKDMAASEVEKLVLADEAVQRALSGGAPKKLIVVPGRIVNVVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBTN2_HUMAN
Sequence: MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI
What is the function of this protein?
Acts with TAL1/SCL to regulate red blood cell development.  Also acts with LDB1 to maintain erythroid precursors in an immature state.
What are the official names of this protein?
Rhombotin-2, Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, T-cell translocation protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: MUTS_LACH4
Sequence: MMEQYYEIKKQYPDAFLFYRVGDFYELFEDDAVKGAQILELTLTHRSNKTKNPIPMAGVPHMAVDTYVNTLVEKGYKVALCEQLEDPKKAKGMVKRGIIQLVTPGTMMNEGPNDAKDSNYLTSVVTTKSGFGLAYSDLSTGEIYSTHLKSFAAVSNELLSLRTREVVYNGPLTEQSKDFMHKANITVSAPTPIEGEHAEISYVEQNLTNGAEKSATRQLVGYLLSTQKRSLAHLQIAKSYEVNQYLQMSHTVQNNLELVASAKTGKKMGSLFWVLDKTHTAMGGRLLKQWLARPLLNVDIINHREKMVQALLDGYFTRENTIDALKGVYDLERLTGRIAFGNVNARELLQLSRSLQAVPVILDALNQSDSDVLTDFAKKIDPLKGVAELISTTLVKDPPLLTTEGGLIRDGVDKQLDRYRDAMNNGKKWLVQMETDERQKTGIENLKVGFNKVFGYYIQVSNGNKSKVPLDRYTRKQTLTNAERYITPELKEHENLILEAQTRSTDLEYDLFVQLRDEVKKYIPALQKLGNQLAALDVYCGFATVAEQNNYCRPSFHTDSQDIDVVNGRHPVVEKVMTAGSYIPNDVKMDSATNIFLITGPNMSGKSTYMRQMALIAIMAQVGSFVPADSAALPIFDQIFTRIGAADDLISGQSTFMVEMSEANAALQYATKRSLVLFDEIGRGTATYDGMALAGAIVKYLHDKVGAKALFATHYHELTSLDETLDYLKNIHVGATEENGKLIFLHKILPGPADQSYGIHVAQLAGLPRAVLREATKLLKRLEAQGSELAPVSQQLDLFAQPEAASDEVDDNNSENSPMTDAEQEVLDDISNLYLADKTPLQIMQMVANWQKDLKDDK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: NU4LM_MICKK
Sequence: MSPAVLNITMAFTFSLLGTLMFRSHLMSTLLCLEGMMLSLFMLATITPLNTHSMIMFPIPIAILVFAACEAAVGLALLAKISNTYGSDFVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BIOD_FRACC
Sequence: MTALVVTGTGTGVGKTVVTAAIGALAHDRHHAVAVVKPAQTGVGPGELGDVDLVRDLTGITDVHELARYPDPLAPATAARRSGHRAVDLDELAARIGTLADSRDLVLVEGAGGLLVRYDAGGATLADLARVLRAPVLVVTAAGLGALNDTALTLEALAHRGLDLAGVVVGSWPAEPDLACRCNLIDLESLAARPLAGVLPAGAGLLARLEFLAVARASLQPALGGTFRAQEFRARYET
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRX4_PENRF
Sequence: MIPRWQPASIPLLLHLDTLRCHHVSVQPPRATMTSLNIKEEDIPRLDGKVVVISGGASGIGLAAANIFARAGAKIFLFDRNPPDSGEAPENSTFIKADITSWAELKAAFAQAGHVDIAVANAGVSEEQPYFEDTFDEQGELKEPGFAVVDVNFKGTVMFTKLAVSYMRKQGKGGSVVITASATGYAPEQNLPVYSAIKSGLVGLVRSLRSTLPRFDISINAVAPAATITKLLPMDIAGPLMAAGLPVSSAHMVGLAVVYSAVARQPRMVETYGKENVLDLESKWNGRTILTLGEHYTELEEKLADLRPVWFGWRNTDLTKKQQATADFR
What is the function of this protein?
Short-chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of PR-toxin, a bicyclic sesquiterpene belonging to the eremophilane class and acting as a mycotoxin (PubMed:24239699, PubMed:27921136).  The first step of the pathway is catalyzed by the aristolochene synthase which performs the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene (PubMed:8440737, PubMed:15186158, PubMed:24239699).  Following the formation of aristolochene, the non-oxygenated aristolochene is converted to the trioxygenated intermediate eremofortin B, via 7-epi-neopetasone (PubMed:24239699, PubMed:26274339).  This conversion appears to involve three enzymes, a hydroxysterol oxidase-like enzyme, the quinone-oxidase prx3 that forms the quinone-type-structure in the bicyclic nucleus of aristolochene with the C8-oxo group and the C-3 hydroxyl group, and the P450 monooxygenase ORF6 that introduces the epoxide at the double bond between carbons 1 and 2 (PubMed:24239699, PubMed:27921136).  No monoxy or dioxy-intermediates have been reported to be released to the broth, so these three early oxidative reactions may be coupled together (PubMed:24239699).  Eremofortin B is further oxidized by another P450 monooxygenase, that introduces a second epoxide between carbons 7 and 11 prior to acetylation to eremofortin A by the acetyltransferase ORF8 (PubMed:16345540, PubMed:24239699, PubMed:27921136).  The second epoxidation may be performed by a second P450 monooxygenase (PubMed:24239699).  After the acetylation step, eremofortin A is converted to eremofortin C and then to PR-toxin (PubMed:24239699).  First the conversion of eremofortin A to eremofortin C proceeds by oxidation of the side chain of the molecule at C-12 and is catalyzed by the short-chain oxidoreductase prx1 (PubMed:16345540, PubMed:24239699).  The cytochrome P450 monooxygenase ORF6 is probably also involved in this step (PubMed:27921136).  The primary alcohol formed at C-12 is finally oxidized by the short-chain alcohol dehydrogenase prx4 that forms PR-toxin (PubMed:16345540, PubMed:24239699).
What are the official names of this protein?
Short-chain dehydrogenase/reductase prx4, PR-toxin biosynthesis cluster protein 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TIG_CUPNH
Sequence: MSNVIENLGKLDRKVTLAIPKAEVEKEKQERLVRLSKTVKMSGFRPGKVPMKMVEKQYGQQVEFEVRFDKAARKFFDITKEQDVKVAGQPKFEIKNEGVGEDEVAFDATFEVYPEVTIGDLSAAEVTRTGTEITDAEVDKTIDILRKQRVHYHARGEAGEHGDGGADVAAQNGDRVTLDFVGKIDGEEFAGGKAEDFPFVLGEGRMLPEFEQAALGLKVGESKTFPLAFPEDYHGKEVAGKTAEFTVTLKKIEWAHLPEVNDAFAKSLGIADGSVEKMRADIRENLEREVKRRTHSMLKDQVMEALLKASELEVPKALIEQDQERLVEMARRDLEQRGMPNAKDMPIPAEMFAQQAERRVKLGLILAEIVKANGLEAKADQIKAEIEDFAKSYEDPKEVMRWYYGDQQRLAEMEAYVLENNVVNFVCGKAKVTDKKVSFEELTAEGNQQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HM02_CAEEL
Sequence: MTLKFSVERLVDSEKESEEADVEEQNNLKKLEEDEEDDELCEKSGKNEPLSQTLSYFDVLLPHVQMACSNPFISGIGASGSGDQNLNTGAGGSVWQHPWLELLQSTTAAQFGDVTAGLFLQPLRKNKRIRTAFSASQLIQLEKAFEGNHYVVGNERKQLAAKLSLTETQVKVWFQNRRTKHKRVRLEGSDPNAPMSNDEDDEDDKKSVS
What is the function of this protein?
Required for activity of the M3 pharyngeal motor neuron.
What are the official names of this protein?
Homeobox protein ceh-2.
What is the protein family that this protein belongs to?
Belongs to the EMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABV_BURA4
Sequence: MIIKPRVRGFICVTTHPVGCEANVKEQIDYVTSHGPIANGPKKVLVIGASTGYGLAARISAAFGSGADTLGVFFERAGGETKPGTAGWYNSAAFEKFAAEKGRYARSINGDAFSDKVKQVTIDTIKQDLGKVDLVVYSLAAPRRTHPKTGETISSTLKPVGKAVTFRGLDTDKEVIREVSLEPATQEEIDGTVAVMGGEDWQMWIDALDEAGVLADGAKTTAFTYLGEQITHDIYWNGSIGEAKKDLDKKVLSIRDKLAAHGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEQGTHEGCIEQVYGLLKDSLYGATPHVDEEGRLRADYKELDPQVQGKVVAMWDKVTNENLYEMTDFAGYKTEFLRLFGFEIAGVDYDADVNPDVKIPGIIDTTV
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: MSCL_ACIBT
Sequence: MSIIQEFKEFAIKGNMMDLAIGVIIGGAFGKIVDSLVKDIIMPLITVITGGGVDFSQKFIVLGANPNNLQSLDALQKAGINVLTYGNFLTILINFLILAWVVFLMVKLLNKLRRDKNEPEAPAATPEDIQLLREIRDELKKQA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECA_ROSDO
Sequence: MLGIGTISRKIFGSPNDRKVKATRPVIAQINALEPEFEKLSDEGLKEKTEEFRKRALEGESLDALLPEAFANCREAARRALGLRAFDTQLMGAVFLHQGNIAEQKTGEGKTLTATFAAYLNGLTGRGVHIVTVNEYLAKRDAAWMGSVFGALGLTTGVAYSDMPEDEKRKAYASDITYATNNELGFDYLRDNMKSELDQIYQKQHNFAIVDEVDSILIDEARTPLIISGPSQDRSEMYKTVDAVIPQVRDDHFELDEKTRNVTFTDEGNEFLEEILHAQGLLEEGQSLYDPESTTVVHHVNQGLRAHKLFQRDKDYIVRDDNVVLIDEFTGRMMPGRRLSDGLHQAIEAKEGVDIKPENITLASVTFQNYFRLYDKLSGMTGTALTEAEEFMEIYGLGVVEVPTNKPIARVDEDDQVYRTAREKYEAMLEKIKESNAKGQPVLVGTTSIEKSEMLSNMLKQAGITHNVLNARQHEQEAQIVADAGKYGAVTIATNMAGRGTDIQLGGNVDLQVMNALTADPDADPEALRASIEAQHADEKAKVLAAGGLYVLASERHESRRIDNQLRGRSGRQGDPGRSSFFLSLEDDLMRIFGSERLEKVLKTLGLKEGEAIVHPWVNKSLERAQSKVEGRNFDIRKQLLKFDDVMNEQRKVIFGQRREIMEAKDLSEITTDMRHQVIDDFIEQYLPPNTYADQWDAEGLYAAVQEQLGIDVPVMDWVEEEGVDDEAIRERLVEATDKLMTEKAGQFGAENMRNIEKQLLLQAIDTKWREHLLTLEHLRSVVGFRGYAQRDPLNEYKNESFQLFESMLDSLREDVTQKLSQIRPMTEEEQQAMIEQIRAQQAAAQAAAAGPTVSAQAGPVAGPADAAVAFDENDPSTWGNPGRNEPCPCQSGKKFKHCHGRLI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: GCH11_PSESM
Sequence: MSSSLPQHYRDILLELGENPEREGLLDTPKRASKAMQYLCHGYTQTVEEIVNGALFASDNDEMVIVQNIELYSLCEHHLLPFIGKAHVAYIPTGKVLGLSKIARIVDMFARRLQIQENLTKQIADSIQQVTGAAGVAVVIEAQHMCMMMRGVEKQNSTMNTSVMLGAFRESSTTRMEFLQLIGRSRT
What are the official names of this protein?
GTP cyclohydrolase 1 1, GTP cyclohydrolase I 1, GTP-CH-I 1.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CH60_STRA3
Sequence: MAKDIKFSADARSAMVRGVDILADTVKVTLGPKGRNVVLEKAFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGLKNVTAGANPIGIRRGIETAVSAAVEELKEIAQPVSGKEAIAQVAAVSSRSEKVGEYISEAMGRVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVSELENPYILITDKKISNIQEILPLLEEVLKTNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVVTEDLGLDLKDATMQVLGQSAKVTVDKDSTVIVEGAGDSSAIANRVAIIKSQMEATTSDFDREKLQERLAKLAGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVSGGGTALVNVIEKVAALKLNGDEETGRNIVLRALEEPVRQIAYNAGYEGSVIIERLKQSEIGTGFNAANGEWVDMVTTGIIDPVKVTRSALQNAASVASLILTTEAVVANKPEPEAPTAPAMDPSMMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YG1I_YEAST
Sequence: MAKTIKVIRKKDPKKKNLSDPLAKQKLVWKIGHVLTLVFGLLFSITYFYHVLIFFKYRSWKWLFLRVNKNYSFIQSKRWYMKLLSWSPQVMYRLSLIGVFMSESVTMQQNWVGLNPTWNDLLSSENFHTLLIACLWFFGGGKSFYKILPYMILSYLHLTKMNYELNANKEEKIPLTPKDRKMLHLLAYSELLVILALTLDTILFKTGTSGFMLVIYVGIYWLRLNFSPYAQVAVLELLVKFEKYVPKKYRDKWQVIKNFIYMKMKEHEKRTEEVARYA
What are the official names of this protein?
Uncharacterized membrane protein YGR026W.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL36_ALTMD
Sequence: MKVRASVKKICRNCKVIKRNGVVRVICSSDPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TTDB_ECOUT
Sequence: MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELKRPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGKGGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEFGPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK
What are the official names of this protein?
L(+)-tartrate dehydratase subunit beta, L-TTD beta.
What is the protein family that this protein belongs to?
Belongs to the class-I fumarase family.
Protein: ECOT_PSEPK
Sequence: MRPTPMTAILALSLAAAAPAMAASLKDIAPYPEAEKGFTRQVIHLPAQADESAYKLEILAGKTLQVDCNRQRLGGNLEAHTLEGWGYNYYRLDNVSGPASTLMACPDGKKTEAFVPVVGDGFLLRYNSKLPVVVYVPKDVEVRYRVWSASQDVQKAKVE
What is the function of this protein?
General inhibitor of family S1 serine proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUDL_ECODH
Sequence: MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASAIAAALREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDSHRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
What is the function of this protein?
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
What are the official names of this protein?
Uncharacterized Nudix hydrolase NudL.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: RL29_KLEP7
Sequence: MKAKELREKSVEELNAELLNLLREQFNLRMQAASGQLQQTHLLKQVRRDVARVKTLLTQKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: Y555_METJA
Sequence: MSVVEYLKKLSKLHGISGREDSVREFMKKELEKYCDSVEIDNFGNLIAKRGNKGKKIMIAAHMDEIGLMVKYIDDNGFLKFTKIGGIYDPTILNQKVVVHGSKGDLIGVLGSKPPHRMKEEEKTKIIKYEDMFIDIGAESREEAIEMGVNIGTWVSFLSEVYDLGKNRLTGKAFDDRVGCAVLLEVMKRLSEEDIDCQVYAVGTVQEEVGLKGARVSAFKINPDVAIALDVTIAGDHPGIKKEDAPVDLGKGPVVGIVDASGRGLIAHPKVLDMIKAVSEKYKIDVQWEVGEGGTTDATAIHLTREGIPTGVISVPARYIHTPVEVIDKRDLEKTVELVYNCIKEVNNFF
What are the official names of this protein?
Putative aminopeptidase MJ0555.
What is the protein family that this protein belongs to?
Belongs to the peptidase M42 family.
Protein: WETA_PENCA
Sequence: MFAQPYDHSFNDLFNQYVNMETSAADGKDSALSDFDQLFPLDSLSSDCGDLPPTVSTPKRHQSPQPWSNDWSLQNDGAAVDHFAFHDTVHPSAISDVNLNNFEVPSRPTATHALSTSPSTPPATPRRKPTQSALITPKSIRHRSPNERRSHLRKQSFSPSLMRSSNLSKSRMAYPEAWAQQIQNFSLHSSEDRLPLSPPPSDVLIQHENMPTEHIMNQPRDSAEMPPQYDARLYHQSPSVSCHRRTSQCQHASNSTTLITKLFHLDSSSPSSADDMFSSSHSSDPHSISSWQSDPLHASSLSFTPDLQGQDSQWWSPMPSRVAQQQASYLESPTPVRTTQNVGNQNDIMQGGLMIQFNPSYDMSADHSFSSSNMLPATPQKFDTSFTTSQIHNVSRSPSLSPKAGTSPRDIHNGSISKPTHRRTHSRKLSGQSMNAPKPAKASGSSSRGSNKSVSVSFVNFTAHDSKKILTGVAPSGSSKTKARREQEARDRRRKLSEAALRAVRSAGGDVEALEAVLC
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation (By similarity).  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (By similarity).
What are the official names of this protein?
Developmental regulatory protein wetA.
What is the protein family that this protein belongs to?
Belongs to the wetA family.
Protein: ARMOM_ARMGA
Sequence: MPSSLKLLSNLIAESVDKIEQRCAAQGVPFPELNEVLSFQSEAIRSDTDVAEAIQVIAASAAQLLATAMSPIATLSVVAHQWDVPACLGAANDANVAEILRDAGPKGAHIDDIAKRNGTNAGRLGRVLRLLASHHIFREVSPDVFANNRISSLLDSKKPVEELEKNPQSKYTETSLVNTFVSFGAGEFFKGGAFLSETLRDPVFGHSDEANHSAFNKAFKFDVSFFEWMERPENKDVLSRFSLMMRATTDLLPDAAILNGFDFGSLPDGALVVDVAGGIGSLSMVLAKTFPKLNFVVEDRPQLASDAEPYWKSNLPEALESGRVRLVAHDMFTPQPDLGSPVDVFVLRGILHDWADSYGIRLLSHLRAAAGPQTKLVVIEILLESPCRDPETSTIKGCEPRTVPEPLLANMGAADSVDYSMDMMMMGFGNGQERTLRHYVKILSETGWELKEVIHIDSLHIGPLRPHLIAVPV
What is the function of this protein?
O-methyltransferase, part of the gene cluster that mediates the biosynthesis of melleolides, a range of antifungal and phytotoxic polyketide derivatives composed of an orsellinic acid (OA) moiety esterified to various sesquiterpene alcohols (Probable).  The first step in melleolides biosynthesis is performed by the delta(6)-protoilludene synthase PRO1 which catalyzes the cyclization of farnesyl diphosphate to protoilludene (PubMed:21148562).  The orsellinic acid synthase armB produces OA by condensing acetyl-CoA with 3 malonyl-CoA units in a three-round chain elongation reaction folowed by a C2-C7 ring closure (By similarity).  ArmB further catalyzes the trans-esterification of OA to the various sesquiterpene alcohols resulting from the hydroxylation of protoilludene (By similarity).  The melleolides cluster also includes 5 cytochrome P450 monooxygenases, 4 NAD(+)-dependent oxidoreductases, one flavin-dependent oxidoreductase, and one O-methyltransferase (By similarity).  The cytochrome P450 monooxygenases may be involved in protoilludene hydroxylation to elaborate melleolides with multiple alcohol groups, such as melleolide D, which carries alcohol functionalities at C-4, C-5, C-10, and C-13 (By similarity).  The role of the NAD(+)-dependent enzymes remains unknown (By similarity).  Numerous melleolides, including arnamial, show 5'-O-methylation of the aromatic moiety which may be catalyzed by the methyltransferase encoded in the cluster (By similarity).  The flavin-dependent oxidoreductase might represent the dehydrogenase yielding the aldehyde in position 1 of arnamial and other melleolides (By similarity).  Finally, several halogenase localized outside of the cluster, are able to catalyze the transfer of a single chlorine atom to the melleolide backbone, resulting in a 6'-chloromelleolide product (By similarity).
What are the official names of this protein?
O-methyltransferase ARMGADRAFT_1088206, Melleolide biosynthesis cluster protein ARMGADRAFT_1088206.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.