PharMolix/UniProtQA huggingface dataset:
Protein: YL629_MIMIV
Sequence: MCIIADSVKNVSNTKIASFHVAYSVDNNKNMIPSQLIVYAAKIDSTVSSNAIILPVYNPGNDSSKIIPLDLSNFSDFFDKLSTIYGRWFIDDNKIQALSYRNGQISVTNSILQVYTVGDYRFSIMPSKKYFNNLDKSQLNVDPRSKISIDQHNNDYSFIVFQFYQKGVIDITPFGYLCPTNSTSQIVPTIHGHPENNDFMPMDMGINISRMQVFSSIDQFNTPIGGRHNNNFENEAEFDHEIYLLVKDTISAGKSTTQDVIDINNLLKKITHDYANNQIRLFVPKNFIPGKIKITGKKPNRNIFVGPNNYRFMNDLLIDNQK
What are the official names of this protein?
Uncharacterized protein L629.
Protein: GPDA_TERTT
Sequence: MTNSLRVAVLGGGSFGTAIANIIAANGHHTYLWMRDEDRAEKCQFERENPEYLPGYKLNDNLEITSDLVASVADADVVTLSVPSQSFREVARRVAPHIPENAIVLSTTKGIEGESFLLMSQILEQELGNVRIGVLSGPNFAKEIIQNQFTGSVIASEHDSVIQCIQQVFASKTFRIYANTDRYGVELGGALKNIYAIVTGMAAALGCGSNTQAMLLTRSLAEMTRLATALGANGMTFLGLAGVGDLILTCTSDLSRNYRVGYAIGKGESLAQVLDNIGQVAEGVNTVKIVKDKADEMGIYMPLVTGLHEVLFEGKDILEVVTGLMTGAMASDVDMQGGVQ
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_HELPG
Sequence: MRKIYATGKRKTAIAKVWLTPGKGELSINEQSLNQWLGGHEAIKMKVMQPLLLTKQEQSVDIKAVVFGGGYSAQAEALRHGISKALNAYDIAFRAILKPKGLLTRDSRVVERKKYGKRKARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: AROC_PSEPG
Sequence: MSGNTYGKLFTVTTAGESHGPALVAIVDGCPPGLEISLADLQHDLDRRKPGTSRHTTQRQEADEVEILSGVFEGRTTGCSIGLLIRNTDQKSKDYSAIKDLFRPAHADYTYHHKYGVRDYRGGGRSSARETAMRVAAGAIAKKYLASQGITVRGYMSQLGPIEIPFKTWESVEQNAFFSPDPDKVPELEAYMDQLRRDQDSVGAKITVVAEGVMPGLGEPIFDRLDAELAHALMSINAVKGVEIGAGFASVAQRGTEHRDELTPQGFLSNNAGGILGGISSGQPIVAHLALKPTSSITTPGRSIDIDGNPVDVITKGRHDPCVGIRATPIAEAMMAIALMDHLLRHRAQNADVKVNTPVLGQL
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: MURA2_STRPN
Sequence: MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCVPDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLLGRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYMDTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIIDGVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMTVSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVNHVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITNIEFILRGYSDIIEKLRNLGADIRLVED
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_MARN8
Sequence: MTVSDRWLLPDGVEDILPPLAGRIESLRRDVMDTCQRWGYQLVIPPLIEYLESLFTGTGHDLELQTFKLTDQLTGRMMGVRADMTPQAARIDAHTLGQDGITRLCYAGHVLHTRPRHMLTGRTPIQAGCELFGSGSEAADMEVISLMLETLRVAGLPRLHLDLAHVSIYESLVSDAGFDRDTEAAVFDAMARKSVPELDRLLGECVPGSAGFRLRQLARVSGGVESLADAREILSGASGAIDAALDQLARVADMLNRDFPEVSLGFDFCELRGYNYHTGLVFAAYVPGHGDAVAKGGRYDAIGSDFGRARPATGFSLDIRALVSLGERPFRKAGAIWAPADNDARLEGVISGLRMTETVIRALPDDRETDPSERGCDRQLVNRDGQWVVETIA
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_PSEF5
Sequence: MSACQTPIIVALDFPTRDAALKLADQLDPKLCRVKVGKELFTSCAAEIVGTLRDKGFEVFLDLKFHDIPNTTAMAVKAAAEMGVWMVNVHCSGGLRMMAACREVLDQRSGPKPLLIGVTVLTSMEREDLAGIGLDIEPQEQVLRLAALAQKAGMDGLVCSALEAQALKSAHPSLQLVTPGIRPAGSAQDDQRRILTPRQALDAGSDYLVIGRPISQAADPAKALADVVAELAL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: PSAA_CAPBU
Sequence: MIIRSPEPEVKILVDRDPIKTSFEEWAKPGHFSRTIAKGPDTTTWIWNLHADAHDFDSHTSDLEEISRKVFSAHFGQLSIIFLWLSGMYFHGARFSNYEAWLSDPTHIGPSAQVVWPIVGQEILNGDVGGGFRGIQITSGFFQIWRASGITSELQLYCTAIGALVFAALMLFAGWFHYHKAAPKLAWFQDVESMLNHHLAGLLGLGSLSWAGHQVHVSLPINQFLNAGVDPKEIPLPHEFILNRDLLAQLYPSFAEGATPFFTLNWSKYSEFLTFRGGLDPVTGGLWLTDIAHHHLAIAILFLIAGHMYRTNWGIGHGIKDILEAHKGPFTGQGHKGLYEILTTSWHAQLSLNLAMLGSLTIIVAHHMYSMPPYPYLATDYATQLSLFTHHMWIGGFLIVGAAAHAAIFMVRDYDPTNRYNDLLDRVLRHRDAIISHLNWVCIFLGFHSFGLYIHNDTMSALGRPQDMFSDTAIQLQPVFAQWIQNTHALAPGVTAPGETASTSLTWGGGELVAVGGKVALLPIPLGTADFLVHHIHAFTIHVTVLILLKGVLFARSSRLIPDKANLGFRFPCDGPGRGGTCQVSAWDHVFLGLFWMYNAISVVIFHFSWKMQSDVWGSISDQGVVTHITGGNFAQSSITINGWLRDFLWAQASQVIQSYGSSLSAYGLFFLGAHFVWAFSLMFLFSGRGYWQELIESIVWAHNKLKVAPATQPRALSIVQGRAVGVTHYLLGGIATTWAFFLARIIAVG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A1, PSI-A, PsaA.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ZN684_MACFA
Sequence: MINFQESVTFQDVAVDFTAEEWQLLDCTERTLYWDVMLENYRNLISVGCPINKTKVILKVEQGQEPWMVEGVNLHQSSPESDCPLVDEPRKHRESKDNFLKSVLLTFNKILTMERIHHYNMSTSLNPMRKKSCKSFEKRLPPHLDLLNYNRSYTGENAYECRECGKAFKKKFHFIRHEKNHTRKKPFECSDCGKAYSRKAHLVTHQKIHNGERPFVCNDCGKAFMHKAQLVVHQRLHTGEKPYECSQCGKTFTWNSSFNQHVKSHTLEKSFECEECGKTFRYSSSLYKHSRFHTGEKPYQCIICGKAFGNTSVLVTHQRIHTGEKPYGCIECGKAFIKKSHLLRHQITHTGEKPYECNRCGKAFSQKSNLIVHQKIHT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 684.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXB_BURL3
Sequence: MPLPTSQLRLAMVAGEPSGDLLGASLLGGLRERLPESAQYYGIGGQRMIAQGFDSHWQMDKLTVRGYVEALGQIPEILRIRGELKRQLLAERPDAFIGVDAPDFNFNVEQAARDAGIPSIHFVCPSIWAWRGGRIKKIAKSVDHMLCLFPFEPAILDKAGVASTYVGHPLADEIPLEPDTHGARIALGLPADGPVIAVLPGSRRSEIALIGPTFFAAMALMQQREPGVRFVMPAATPALRALLQPLVDAHPKLALTITDGRSQVAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAGRFVVPELLQHFATPEALADATLTQLRDDANRRTLTEIFTEMHLSLRQNTAAKAAEAVVRVLEQRKGRA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: SYH_SHEB2
Sequence: MAKQIQAIRGMNDILPTQSPLWQKVEAVLRSSVSAYGYSEIRTPIVENTDLFKRSIGEVTDIVEKEMYTFADNNGDSLTLRPEGTASTVRAGNENGLLYNQEQRLWYMGPMFRHERPQKGRYRQFNQFGVEVYGIGTADIDAEVLMLSARLWEKLGISDHVSLELNTLGDPAERAVYRDALIAFLEQHKDALDEDSKRRMYSNPLRVLDSKDQNVQAILAGAPELMDFLGEESKTHFSQLRELLDAVGIKYTINPRLVRGLDYYNRTVFEWVTSSLGSQGTVLAGGRYDGLVAQLGGKDTPAVGFAMGLERIVLLLETLELNKDIPSEVDVYVTAMGDSCLVEAIKIAQELRSALPNLKVMSHCGGGNVKKQMKRADKSGASVALLIGEDELAEGMVTVKHLRNDIEQQRVARSALGAFLAELAIK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_CROS5
Sequence: MTISPQYIWNQVLDRLKLRLNPTAYETWIASATVQTFQDNCLVIQVENPFILNHLQKTYYSLILEEVETIVGYPIAVKLTTSQEQNLRIVDKNKDNLSSTKLQNKRQQESPKLNQLNPRYNFSRFVVGPTNRMAHAASLAVAESPGREFNPLFLCGGVGLGKTHLMQAIAYYRLELYPNANVFYVSTEQFTNDLITSIRQDSMENFREHYRTADILLVDDIQFIEGKEYTQEEFFHTFNTLHEAGKQVVIASDRPPKRIPSLQDRLVSRFSMGLIADIQVPDLETRMAILQKKAEYENIRLPRDVIEYIATNYTSNIRELEGALIRAVTYISISGLSMTVENIAPVLNPPMEQITASPEIIIQIVAENFNVSVEDLKGSSRRREISLARQIGMYLMRQHTDLSLPRIGEEFGGKDHTTVLYSCDKISKLQKKDWDLSQQLSELSDRINIASRNQN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_STRP1
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWEKRRLAYEINDFREGLYHIVNLEATDAAALNEFDRLSKINGDILRHMIVKLDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: COF_ECO81
Sequence: MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKENPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQIQLYEALGERAHLCFSATDCLEVLPVGCNKGAVLTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
What is the function of this protein?
Catalyzes the hydrolysis of 4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2-methyl-5-hydroxymethylpyrimidine phosphate (HMP-P).
What are the official names of this protein?
HMP-PP phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. Cof family.
Protein: PA2BA_PROFL
Sequence: HLLQFRKMIKKMTGKEPIVSYAFYGCYCGKGGRGKPKDATDRCCFVHDCCYEKVTGCDPKWSYYTYSLEDGDIVCEGDPYCTKVKCECDKKAAICFRDNLKTYKNRYMTFPDIFCTDPTEGC
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that displays edema-inducing activities.  PLA-A is three times less active than PLA-B in edema-inducing activity.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 PLA-A, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2628_MYCTO
Sequence: MSTQRPRHSGIRAVGPYAWAGRCGRIGRWGVHQEAMMNLAIWHPRKVQSATIYQVTDRSHDGRTARVPGDEITSTVSGWLSELGTQSPLADELARAVRIGDWPAAYAIGEHLSVEIAVAV
What are the official names of this protein?
Putative uncharacterized protein MT2703.
Protein: AROE_CUPNH
Sequence: MTSTDSSQATSDRYVVIGNPVAHSRSPAIHAAFARQTGEAVQYDRLEAPLDGFADAVRQFFAEGGYGCNVTVPFKLEAYDLADRLTERAEAAGAVNTLWIEEGLIHGDNTDGIGLVRDIQDNLDTLIEGKRVLLLGAGGAAMGAMLPLIECRPSRIVVANRTASRASDMLEEFVEAADQYGVELWGGGLDALDGLSEDEAVDVVINASSSSLHGEVPPVPEFLLGEGVLAYDMMYGAEPTVFLQFAARCGARTSDGLGMLVEQAAEAFYIWRGVRPRTAPVLAELRAALQAERKG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MOAC_CERS1
Sequence: MSGLTHFDESGSAHMVDVSEKPVTARVAVARGAVKMSAETLALVTEGRAEKGDVLGVARLAGIMGAKRTADLIPLCHPLPITKVALELTADPALPGVVVEATVKTGGQTGVEMEALTAVSVACLTIYDMVKAVEKGMEITGIRLLLKEGGKSGRFEASA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PDXS_STRPN
Sequence: MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMALERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDESEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAVRHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPADAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVGINENEIQILMAERGK
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: AGLS_HALVD
Sequence: MKRLAKAAFSQNSLTAPIVSTFVYLISVVRVVLNGNWPVTSSDTAMFQHIGWMVFSGKRYYIDAWDPKPPLTLELATIIAYISNGDPHLQHTLSVVSTIVAGILLTYLISHITSEITGNQFAGLLSGIVFITFPVIHYSAVFGYEPKYFVFLFGLGSIYLSRNPKPILSGAAAAASAGMWQFAIIFPIISFGIISRRKSKDLILKYVFGATIIAFISLLPIYLQGGLVAMTVEVIIAPLYAGETQSFLYRLVKGVTHLKLMIPIALLGMAGILLGFLDDIRERWWVVGLLLWFCIQIFILDYDGADDLFLGIILVSMGIGFAFEKLSTKYESERINSIVTAVVVCMLIWQVVTLGGVGVITNPYSYSGDGPDQAILESGIQQFAHLSGYTEYTIGGSPPDEQYNVKSRYGPDKIEELFFTSTIPSTCHYRLSGMELEWMNLTEQSFTEEKCGKWRLP
What is the function of this protein?
Involved in the assembly of a N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins.  Transfers mannose, the terminal pentasaccharide residue, from its dedicated dolichol phosphate carrier to the protein-bound glycan comprising the first four subunits of the N-linked pentasaccharide.
What are the official names of this protein?
Dolichol phosphate-mannose mannosyltransferase, Archaeal glycosylation protein S.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_DESRM
Sequence: MAEISASMVKELRERTGAGMMDCKKALAEVGGDMEKAIEFLREKGLAAAAKKAGRIAAEGVVESYIHGGGRIGVLVEINCETDFVAKNEDFRGLAKDIAMQIAAAKPEFVRREEVSADKIEKEKEILRAQALNEGKPEKIVEKMVEGRIEKFYKEVCLLEQPFIKDSDKTVQQVINEIIAKIGEKVDVRRFVRYEMGEGLEKRQDDFAAEVAAQIKA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTP1_MACMU
Sequence: MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTMETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTFLRHLGRTLGLYGKDQREAALVDMVNDGVEDLRCKYLSLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVARLSARPKLKAFLASPEHVNLPINGNGKQ
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2).  Participates in the formation of novel hepoxilin regioisomers.  Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
What are the official names of this protein?
Glutathione S-transferase P, GST class-pi.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Pi family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino acids function as un uncleaved transit peptide, and arginine residues within it are crucial for mitochondrial localization.
Protein: GSA_AERHH
Sequence: MSKSDQLFEQARQTIPGGVNSPVRAFNGVGGTPRFIDHADGAYLYDVDGQAYVDYIGSWGPMLLGHNHPAIKAAVIKAVEKGLSYGAPTEIEVLMAEKVRQIVPSMEQVRMVNSGTEATMSAIRLARGYTGRDKIVKFEGCYHGHADSLLVKAGSGALTLGQPNSPGVPADFAKHTLTCVFNDLDSVCEAFTQYGSEIACIIVEPVAGNMNCIPPVPGFLEGLRAICDEAGALLILDEVMTGFRVSLRGAQGHYNIDPDLTTLGKIIGAGMPVGAFGGKKKVMQHIAPTGPVYQAGTLSGNPVAMAAGLTMLDLLLEPGLYEQLSAKTARVAEGLKAAAAKHGIPLAINYVGGMFGFFFTDEPEVTRYEQVTRCDMERFKRFYHLMLEEGVYLAPSAYEAGFLSLAHGDKEIEHTLAAAERSFAKLAG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MO4L1_MOUSE
Sequence: MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRSEKSLKTREDIVALFPVPEGAPSVHHPLLTSSWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRKAV
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.  This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription.  This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair.  The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400.  NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.  Also a component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones.  Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC).  Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci (By similarity).
What are the official names of this protein?
Mortality factor 4-like protein 1, MORF-related gene 15 protein, Testis-expressed gene 189 protein, Transcription factor-like protein MRG15.
What are the subcellular locations of this protein?
Nucleus.
Protein: STKP_STRR6
Sequence: MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVAFAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQNPLPSVIAENSSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYNRRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQAPKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANFEIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSDVIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKATTIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVSKPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVEGMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP
What is the function of this protein?
Protein kinase involved in signal transduction pathways that regulate various cellular processes.  Likely senses intracellular peptidoglycan subunits present in the cell division septa of actively growing cells; thus, intracellular unlinked peptidoglycan may serve as the signal molecules that trigger StkP phosphorylation activity on a set of substrates.  Plays a crucial role in the regulation of cell shape and cell division of S. pneumoniae through control of at least DivIVA activity.  Identified target substrates that are specifically phosphorylated by StkP in vivo, mainly on threonine residues, are DivIVA, KhpB (also called EloR/Jag) and StkP itself.  Autophosphorylated StkP is a substrate for the cotranscribed protein phosphatase PhpP (shown in the avirulent strain Rx / Cp1015); PhpP and StkP appear to constitute a functional signaling couple in vivo.
What are the official names of this protein?
Serine/threonine-protein kinase StkP, Ser/Thr-protein kinase StkP, Eukaryotic-type Ser/Thr protein kinase, ESTPK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=The kinase domain is located intracellularly, while the C-terminal PASTA domain is exposed extracellularly. Localizes to the midcell division sites. Time-lapse microscopy shows that StkP displays an intermediate timing of recruitment to midcell: StkP arrives shortly after FtsA but before DivIVA. Furthermore, StkP remains at midcell longer than FtsA, until division is complete. Delocalizes from the septum in the presence of antibiotics that target the latest stages of cell-wall biosynthesis and in cells that have stopped dividing.
Protein: RIBBA_ENDTX
Sequence: MKNKVFASIGDAVKDIKVGRMVIVVDDPGRENEGDLICAAEKASPEVINFMTKYARGLICVPMKHERLKELEIENMVEKPTEKKGCSFTVSVDYKIGTTTGISAYDRSVTVRKLIDKTAKHEDFARPGHIFPLRCKEGGVLARTGHTEAAVDLVRLAGFYPAGIICEIMNNDGTMARMSDLIKFAKKHDLHIITIGELVNYRRRTEKFISEIVNVDLPTRYGDFKLVLFEDLITKDSHIAVVKGVVKNRQNVLVRVHSSCETGDIFHSLRCDCGDQLETALKAVGEAEQGVVLYIHQEGRGIGLANKLKAYRLQEKGMDTVEANKALGFDPDLRDYGIGAQMLSELGIKSINLMTNNPGKINGLESYGLKITKRVPLEISPSKSNEKYLKTKKEKMGHMLKKV
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: YIP1_SCHPO
Sequence: MAYYNNPANLQYYDYSYTADNSFNTQSRAAGFYDEPLHEPLSQGWLAAFSTSGYPGEPSLLEELEINFGHIKQKTTHVLNPFKHVDVHIMDDTDMAGPILFCLLFSTFLSLHGRSHFGYIYGIALLGSLSLHFVLRLMSAKNLFFTRTVSVLGYSLLPLVVIAFFKNIFTFNGIAGYALAALACIWCTYAASAMFVGILQVNNMRFLVAYPIALFYGVFAVITVFSK
What is the function of this protein?
Required for fusion of ER-derived vesicles with the Golgi during ER-to-Golgi protein transport, probably by mediating correct membrane localization of ypt1.
What are the official names of this protein?
Protein transport protein yip1.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.