PharMolix/UniProtQA huggingface dataset:
Protein: O16B_CONCL
Sequence: MKLTCVLIIAVLILTACQFIAADNTEYRKWRRSGTSTGMRLGSRDCGPWCWGQNKCCPDESCRSLHESCT
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal6.11, Conotoxin Cal6.2, Conotoxin Cl6.11, Conotoxin Cl6b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PDRP_GEODF
Sequence: MQRIYLFSDATGETVERVVRAALTQFRNVDVKLHRMSRLRTREDISISLDEAAKQPGVIFYTLVDNELAQYLYNEANLRQLEAIDLITPLLYRLASLLGIQPQKEPGLLYQLNSEYYKRMEAVDFTVKQDDGQEPRNLHKADIVLVGVSRTSKTPLSMYLAHKGYKVANVPLVMGIEPPSELYQVDNSRVVGLMIDAQRLVDIRTARLRNMRQNPRGSYADYQRVEEELDFCRRIYRKHPQWQVIDVTNKSVEESAAEILRRFETGIKD
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: NU5M_TRIRU
Sequence: MYLVIIFLPLLGSIISGFFGRKIGVQGAQLITSSFIIITTMLAIFNFFEVGYNNIPLEINLFRWIDSESINILWGFYFDSLTVSMLIPVLIVSSLVHIYSIGYMSHDPHNQRFFSYLSLFTFMMIILVTANNYLLMFLGVEGVGVCSYLLVNFWFTRIAANQSSISAFLTNRVGDCFLTIGMFIIIWSFGNLDYSTVFSLAPYFNQEFITLIGICLLIGAMAKSSQIGLHVWLPQAMEGPTPVSALIHAATMVTAGVYLLMRSSPLIEYSSTVLILCLWLGAITTIFSSIIGLFQQDIKKVIAYSTMSQLGMMVIAIGLSSYNLALFHLVNHAFYKALLFLGAGAVIHSVSDNQDFRKYGGLKPFLPLAYSIMLIASLSLVAIPFMSGFYSKDFILESAYGQFYISSTLVYFIATIGAMFTTLYSVKVLYLTFLTNPNGPLNNYKNVDQGNIFINLPLIILAIFSIFFGYLTKDVFIGLGTSFFIDNRYFIHPSHEIMLDTEFALPTLFKLLPLFFTITLSIIGIMFSEFFGNLLIKFKFTNLGYNIFSLFNQRFLIEFFYNNYITNFVLKLGGQTTKVLYKGSVELLGPYGLEKRLLNLSKNIGSLSTGVITSYALYILIGLIFYVFLLYLNIDNNILLLLLFGIFSTINKK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FIB12_BPB03
Sequence: MQKPELRRFEKLGEMMVQVYERYLPTAFDESMTLLEKMNKIIEYLNQIGRLTNDVVEEWNKVMEWILNDGLEDYVKETLEKWYEEGKFADLVIQVIDELKQFGVSVKTYGAVGDGKTDDIEAFEKAIASGYPVYIPNGKFAVSRSIKIPSNTVITGAGIDNAVVTFLDSVPLGDSLMINDNYATGNENIYLSDFTLDGNCQRFGVNAIGSGGSRDSNLSIHASKNVHINRIKSINATLHGIDITCGGLDYPYMGDGTTAPYPSRDIYISDCEAPSLGDDGITTNNSEYITISNCNCHDPRLLNNCNGIEIDDGSRHVQLSNNISKNCFGGVEVKAHGNVPAAYNVSINGHMSIGDVRSYNFRHIGHHSATDPESMSAKNIICNNLMSVNPNNKRGFQNNAAPRVLAVSAYYGVVVNGLSAYTTEPANLTETAISVQFRARNVSLSGIVMTGFSMAENAIYVIGGSRGGDSVNISNVTLNNSGRNGVAIGSGIDNVSISNVSAIGDGIANPIAIVKTVNSNPQISGVNGIGYPTVCQVAGVAYNDGLTLFNGAFRGATSSSEFIHSEGFVLGSTSKSGATASKSGVVSSSNSIAKAERSLIAGSASCTTSGSYNTILSSLNCETTDTGNLISTSSASKATGNRNIILASYGVLASGSYKVNGGYGGEGTPSASNIKLGNSLNGHIKAKNTVTGANTWSDYGEYFESVDGQAIETGYLVTLEGSKIRKAQEGEKIIGAISETAGIILGESTWNWQGQYLKNEFGGLIYETVEIDEGVFEKMPKINPSYNPKLEYLSRGERPEWNIVGLIGQIMVRIDDTVKIGSGISAKDGIATDGDTGIVMQITTPYESSKGYGVAKVLLK
What is the function of this protein?
Structural component of the 12 appendages that hang from the lower collar.  Adhesion protein that binds to the host cell surface during virus attachment and mediates teichoic acids degradation.
What are the official names of this protein?
Pre-neck appendage protein, Gene product 12, gp12, Late protein GP12, NP1, Protein p12.
What are the subcellular locations of this protein?
Virion. Note=Present in 36 copies in the virion.
Protein: PPS_THEKO
Sequence: MVNIPKSHPRYWSLYYREKIIEGMEKGMTAKAGLIAHGRGEAFDYLIGERTIEPAERAMRAAVAKFLLAEHPVISVNGNVAALVPKETIELAKALNAKLEINLFYRTEERVRTIAEELRKYDPEIEILGINPTKRIPGLEHERGKVDENGIWKADVVLVPLEDGDRTEALVRMGKFVVTVDLNPLSRSARMADITIVDNIVRAYPRMVELAREMKDYSREELLKIVGEYDNGKTLSDVLLHIRDRLTRLAEEGIWRRKELE
What is the function of this protein?
Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway (PubMed:19666462, PubMed:22940806, PubMed:24638914).  Cannot use (R)-pantoate as substrate and thus does not display pantothenate synthetase (PS) activity (PubMed:19666462, PubMed:22940806).  Displays strict specificity for its natural substrates, 4-phosphopantoate, ATP and beta-alanine (PubMed:22940806).
What are the official names of this protein?
4-phosphopantoate--beta-alanine ligase, Phosphopantothenate synthetase, PPS.
What is the protein family that this protein belongs to?
Belongs to the archaeal phosphopantothenate synthetase family.
Protein: ASNA_TREPA
Sequence: MEKSFILQQQGISFAKHTFTQKLMEHLGLIEVQGPLLSQVGDGIQDGLSGREKAVSVSVKQIPGTAFEVVHSLAKWKRHTLARYGFQDNEGLFVHMIALRPDEDFLDQVRSVCVDQWDWEKVVPVGSRNLAYLKDTVRKVYGALRESEVLVSERFGLRAFLPADIVFVQSEELVRRYPHLDSKGREDAICKEHGAVFLIGIGGVLSDGKPHDVRAPDYDDWTTPSEGEYKGLNGDILVWNPVLGRAFEVSSMGIRVDEGALRTQLALTGDEDSLACSWHQDLINGRLPQSIGGGIGQSRLAMLLLQRKHIGEVQASVWPRSVREEFENIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDE1_ARATH
Sequence: MEARIGRSMEHPSTPAINAPAPVPPPSTRRPRVREVSSRFMSPISSSSSSSSSSSAGDLHQLTSNSPRHHHQHQNQRSTSAQRMRRQLKMQEGDENRPSETARSLDSPFPLQQVDGGKNPKQHIRSKPLKENGHRLDTPTTAMLPPPSRSRLNQQRLLTASAATRLLRSSGISLSSSTDGEEDNNNREIFKSNGPDLLPTIRTQAKAFNTPTASPLSRSLSSDDASMFRDVRASLSLKNGVGLSLPPVAPNSKIQADTKKQKKALGQQADVHSLKLLHNRYLQWRFANANAEVKTQSQKAQAERMFYSLGLKMSELSDSVQRKRIELQHLQRVKAVTEIVESQTPSLEQWAVLEDEFSTSLLETTEALLNASLRLPLDSKIKVETKELAEALVVASKSMEGIVQNIGNLVPKTQEMETLMSELARVSGIEKASVEDCRVALLKTHSSQMEECYLRSQLIQHQKKCHQQECTTSV
What is the function of this protein?
Microtubule-associated protein required for seed development and for microtubule function in the endosperm.  Associates with nuclear microtubules during mitosis.  Binds to microtubules of the spindle and spindle-poles and to midzone microtubules out of which the phragmoplast emerges.  Not associated with cortical microtubules.  Required for endosperm cellularization.  May be bound and sequestered by GRF5 in an inactive soluble form during the early stages of mitosis.
What are the official names of this protein?
Protein ENDOSPERM DEFECTIVE 1, Protein EMBRYO DEFECTIVE 3116, QWRF motif-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the QWRF family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.
Protein: IF2_FRATW
Sequence: MAEITVGQLAQQTNKEVDALLKQLKSFGIEKSSEKDTLTPTEMKTLLEKINSAKNTATRKKVTSVKLDGKHKINVSVKRKRRVAKKVEQQESTTLEQPQELETMVQEVSQQVDIVKEQDNIEQIVENKEAVKVQEQRQAEIAKPVIKDSGFKITAMPEIKIEEIVAEDDEGLAASDKQAKKKAAKKVFSEAVNTNTKYKREEEEKKSKAKKAGGKGFKKANPRQLSQLAGDLESFDEFGAKKGKLKAPKVKKQEFTKPVENTVRTVEIHEGITVSELAQKMAVKGAEIVKVLFNMGVMATINQSLDQDTAILIVEEMGHKYTLHNENALEEAVTIVDRSSYKKISRAPVVTIMGHVDHGKTSLLDYIRQTRVVAGEAGGITQHIGAYSVKTDKGSITFLDTPGHEAFTSMRARGAKSTDIVILVVAADDGVMPQTEEAIQHAKAARVPIVVAVNKIDKPEADPDKVISELAQRNVIPESWGGDVMFVNVSAKTGEGVADLLEAVLLQSEVLELEAFAEGLAEGVVIESRLEKGRGPVATVLVQNGNLKQGDNILCGTEYGRVRAMHNDLGKKIKAAGPATPVEILGLSGVPAAGDEMVVIENEKKAKELAAQRSQKQKEAKIAQEQSLKLSNMFNNMGKEGEQQVLKIILKGDVQGSVEAIRESLLKLSTDEVKVDIIASGIGAITSSDVTLAVASTAVVIGFNVRADSAAKKLAETDGVEFRYYNIIYDLIDDVKKAMSGLLSPEMKEQIIGIAEVREVYRSSKFGSIAGCMVIEGVVKRTNPIRVLRNNVVIYEGTLESLKRFKDDASEVKKGLECGIGVKNYNDVREGDQIEVFEVAKEL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_MESFL
Sequence: MSVNDLRPGTTFIYEGNLFVVIEQSFSKTGRQQGKVSVKAKNLRTGSRVEITFTGGEKVEKAMIERKDMQYLYNDGTDAYLMDTDTYEQIQIPMTRLEWESKFLTDGLMIKMTEYDGEVLGISLPDKVELEVTEAEAAVKGDTTSGALKKAVVETGLDIMVPLFVNVGTKVIISTTDGKYSGRAQ
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_AQUAE
Sequence: MRVLFCSSEIYPYAKTGGLADFSFCLIKYLKKYGVKVKGVMPYYKTLKAENLRKTDKGVTLNLNGKDYTFEVYESEDCYFLRNDELFGRDYIYGPPGWGYEDNDIRFGGFSRAVSELISTGQLEADVVHANDWQTALIPLFLKEVFKTPVKTVFTIHNLAYQGLFPKETVERVGIPPYLFHMEAVEFWGLVNFMKGGIVFSDLITTVSPTYAKEIQTQEYGYGLEGVLKKYSYKLRGILNGIDYEVWNPEKDKYIYQNYSLRNYSKKFKNKEFLSKELGIEAEKPLISFINRFTHQKGVELILNCAEEMSKLNANFVFLGTGEYENAFLDVSKIYKNFKVFAEFNEGFARKLYASSDFILMPSYFEPCGLTQMIGMRYGCVPIVRKTGGLRDTVKDISEGGYGITFEEPSKETFLCSLKRAIELYENAKKFRNSVKIVMSLDFSCDRMTKEYIECYEEVQSHQ
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: LRK21_ARATH
Sequence: MAGVLGSVVFWLIIGIHVTFLVFAQEGDHFVYYDFRNADLELDGMANTNHGPLHLTNNTNTGTGHAFYNIPIKFTASSLSSFSFSTEFVFAIFPLQKSTYGHGMAFVVSPTKDLRSNGSANSNLGIFNRANDNKTATHIFAVELDTNQNSESFDKGGNDVGIDINSIVSVESADASYFNARKGKNISLPLASGKSILVWIDYDGIEKVLNVTLAPVQTPKPDSPYFSSFIKPKVPLLSRSINLSEIFTETMYVGFSGSTGSIKSNQYILGWSFKQGGKAESLDISRLSNPPPSPKRFPLKEVLGATISTIAFLTLGGIVYLYKKKKYAEVLEQWEKEYSPQRYSFRILYKATKGFRENQLLGAGGFGKVYKGILPSGTQIAVKRVYHDAEQGMKQYVAEIASMGRLRHKNLVHLLGYCRRKGELLLVYDYMPNGSLDDYLFHKNKLKDLTWSQRVNIIKGVASALLYLHEEWEQVVLHRDIKASNILLDADLNGKLGDFGLARFHDRGVNLEATRVVGTIGYMAPELTAMGVTTTCTDVYAFGAFILEVVCGRRPVDPDAPREQVILVKWVASCGKRDALTDTVDSKLIDFKVEEAKLLLKLGMLCSQINPENRPSMRQILQYLEGNVSVPAISFGTVALGIPNISHETVTQMTTTSSSANFSFEDVTVLFGGR
What are the official names of this protein?
Probable L-type lectin-domain containing receptor kinase II.1, LecRK-II.1.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SYP_YERPG
Sequence: MRTSQYLLSTQKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRGEINSYKQLPLNFFQIQTKFRDEVRPRFGVMRAREFLMKDAYSFHTTQESLQETYDAMYTAYSKIFSRMDLNFRAVLADTGSIGGSASHEFQVLAESGEDDIVFSTGSDYAANIEFAEALAPTEPRAPATEELRIVDTPNAKTIAELVEQFKLPIEKTVKTLLVHAHEESGHKLVALLVRGDHDLNEIKAEKLPQVAKPLTFASEEEIRAAIGAGPGSLGPVNLSLPVIADHSVAVMSDFGAGANIDGKHYFGINWERDLALPLVADLRNVVEGDISPDGKGTLQIKRGIEVGHIFQLGTKYSEVMKATVQGEDGRNQVMTMGCYGIGVSRVVAAAIEQNHDDRGIIWPDAIAPFQVAILPMNMHKSFRVKELAEELYTTLRSHGIDVILDDRKERPGVMFADMELIGVPHNIVIGDRNLDSEEVEYKNRRVGEKQMIKTSEIVEFLLSQIKR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MA655_ARATH
Sequence: MSPSSTTTCTSLLEELQMIWDEIGESYNERDKMLLELEQECLDIYNKKVEKTRKFRAELQRSLAQAEAEIASLMSALGEKVSFAKKEGSLKEQISSVKPVLEDLLMKKDRRRKELSETLNQIAEITSNIAGNDYTVSSGSEVDESDLTQRKLDELRADLQDLRNEKAVRLQKVNSYISAVHELSEILSFDFSKALNSVHSSLTEFSKTHSKSISNDTLARFTELVKSLKAEKHERLLKLQGLGRSMQELWNLMETPMDERRRFDHCSSLLSSLPDDALKKGCLSLDIIREAEDEVRRLNSLKSSKMKELVFKRQCELEEICRGNHMDINSDAARKSLVELIESGDGDLSDILASIDGQIEKAREEALSRKEILDKVDKWRHAKEEETWLDDYEKDENRFSAVRGAHKNLKRAEKARSLISKIPAMVDVLTTKVKAWEKERGVPFLCDKQPLLQTLEDDIVIRAQREEEKRQFREQKRLQGQLATEKEAKYGSKSAKKKPLGQSLNTDNVTKTPIGRRIGNTPGRSVTSGGKDYRGNAVIPLNYVALQKDD
What is the function of this protein?
Microtubule-associated protein that bundle and stabilize adjacent microtubules (MT) of the cell cortex.  Confers MT resistance to the drug oryzalin.  Promotes the formation of a planar network of antiparallel microtubules.
What are the official names of this protein?
65-kDa microtubule-associated protein 5, AtMAP65-5.
What is the protein family that this protein belongs to?
Belongs to the MAP65/ASE1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cell cortex. Cell junction, plasmodesma. Note=Present in MT cortical arrays. Binds the preprophase band and the prophase spindle microtubule during prophase. Binds MT during anaphase. Associates also with phragmoplast; binds MT of young emerging phragmoplasts but don't binds along MT when the disk-shaped phragmoplasts transform into a ring-shaped, centrifugally expanding structure. At this time, accumulates in the cell plate and associates with the surface of the separated nuclei. Later traverses the newly formed cross wall, probably in association with plasmodesma.
Protein: SCONB_EMENI
Sequence: MSTEDNHDSQILTARHRSDASEQSFKSLFGGPSSEDGKETEPDTHDHNHSFSNAKAPAKFANQNVAPFLARHIPEQYAPLGAQSILPADLSSANSKYCYRHRPDQKCRRQADEPSMDKLQRELESLPQGDQQSISHVWSLFSAAPAKHRKLILQGIMAQCCFPQLSYISATVRDLIRIDFITALPPEIAFKILCYLDTTSLCKASQVSRGWRALADDDVVWHRMCEQHIHRKCKKCGWGLPLLDRKRLRESKREIELRATTWDKGVVGPRSPDASAESPPSGKRKLEDDEVAVVKRHCSSLGSDAGVDKDSDFFKTRYRPWKEVYKDRFKVGTNWKYGRCSIKTFKGHTNGVMCLQFEDNILATGSYDTTIKIWDTETGEELRTLRGHESGIRCLQFDDTKLISGSMDRTIKVWNWRTGECISTYTGHRGGVIGLHFDASILASGSVDKTVKIWNFEDKSTFSLRGHTDWVNAVRVDTSSRTVFSASDDCTVRLWDLDTKTCIRTFHGHVGQVQQVVPLPREFEFEEHDAECENDDLSTTSGDADPPSIQASMGLEPNAAYSQSSAFGTSFDNGRAAPPRYMVTSALDSTIRLWETTTGRCLRTFFGHLEGVWALGADTLRIVSGAEDRMIKIWDPRTGKCERTFTGHSGPVTCIGLGDSRFATGSEDCEVRMYSFQS
What is the function of this protein?
Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.
What are the official names of this protein?
Probable E3 ubiquitin ligase complex SCF subunit sconB, Sulfur controller B, Sulfur metabolite repression control protein B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MET30/SCONB/SCON-2 family.
Protein: SYH_SHEPW
Sequence: MAKQIQAIRGMNDILPTQSPIWQKLETVLRETVSAYGYSEIRTPIVESTDLFKRSIGEVTDIVEKEMYTFDDRNGDSLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQFGVEVYGIPSADIDAEVLMLSAMLWEKLGITEHVTLELNTLGDSEERAAYRDALIAFLEQHKDVLDEDSQRRMYSNPLRVLDSKNAAVQALLADAPALMDYLGEETRSHFSHLCELLEAVGIQYTINPRLVRGLDYYNRTVFEWVTSSLGSQGTVLAGGRYDGLVGQLGGKSTPAVGFAMGLERIVLLLQTLELDKDIKPAVDVYVTAMGDSCRVEAIKVAQDLRASLPNLKVMSHCGGGNFKKQMKRADKSGAAVALVIGEDELANNQVAVKYLREDKAQELVARDALATYIAELV
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_BLOPB
Sequence: MNCNSNKYPILGLINTPKELRQLSEDHLAKLCNELRQFLLTSVSKSSGHFASGLGTIELTVALHYVYNTPFDYLIWDVGHQAYPHKILTGRRERIFSIRRKNGLHPFPCRDESEYDVLSVGHSSTSISAGLGLAIAAEREMLGRRTVCVIGDGAITAGMAFEAMNHAGFTKSDLLIILNDNEMSISENVGALNNHHTHILSKKVYSNLKVDNNKILSDVLSTNTLIKHIGNQIKNFNGTSSSLFSQLGFNYIGPVNGHDVLELVYILRNIRDMKGPQFLHIITKKGCGYEPAEKDPIKWHAVPKFNPESGSLPVEHSKNITYSAIFGDWLCQVAARDNKIIGITPAMREGSGMSIFSQKYPKQYFDVAIAEQHAVTFAAGLAIAGYKPIVAIYSTFLQRAYDQVIHDVAIQNLPVLFAVDRGGIVGADGQTHQGAFDLSYLRCIPNMIIMTPSDACECKLMLYTGYRYRYGPSVVRYPKGYAVPGNLADTTKLYTLPLSKGVIRRQGNCIAILNFGTLLQSAYNVASKLNATLVDMRFVKPLDENLIKTLAKNHQVLITLEENTVMGGAGSGVNEFIMQNKLSIPVLNIGLPDFFISQGSQSEILSELGLDSIGIYKKIIKWIH
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: LSD1_DROME
Sequence: MATATSGSGLHLEAIDRIGSIPLVESSVKRVETIYDKVKNNNRLFSWYFETAEATISAAYETIQPAVKLFEPSIQRLDNVMCKSLDILEQRIPLVYLPPEMMYWNTKEYMSDHLVRPVLKRADSVKQIGNAVLESPLTTYAAERIDGAFTVGDKFVDKYLVPIQTDQDQTDVKKLVSALNDNFSPIRQQLNRMFGHKSPQEDDNEAVPDERGAIKAIHHGQRFSRKLKRRLTQRTIAEARALKKQSKEAIHVLFYAAELIATDPKQAVQKAKELWVYLSADEPENQARPATLEQLIVLLTRESARRVVHLVNFSAHVAANIPRNLAHTTTEVAHHIIYINHRIITISRLDKVKTISKEEAESLFKRMLAFYGSLQGLTNAYLERVASFLSGRMEAEKVTGSDGGNSNHRSSRRRQDPNHYSATHNNINGVY
What is the function of this protein?
Required for normal deposition of neutral lipids in the oocyte.
What are the official names of this protein?
Lipid storage droplets surface-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
What are the subcellular locations of this protein?
Cytoplasm. Lipid droplet. Note=Cytoplasmic and in lipid storage droplets of adipocytes of first instar larvae. Colocalizes with Lsd-2 on the surface of neutral lipid storage droplets in cells of fat bodies.
Protein: BPHA_COMTE
Sequence: MSSTMKDTQEAPVRWSRNWTPDAIRALVDQDNGKLDARIYADQDLYQLELERVFGRSWLMLGHETHIPKIGDYLTTYMGEDPVIMVRQKDQSIKVFLNQCRHRGMRIVRSDGGNAKAFTCTYHGWAYDIAGNLVNVPFEKEAFCDKKEGDCGFDKADWGPLQARVETYKGLVFANWDPEAPDLKTYLSDAMPYMDVMLDRTEAGTEAIGGIQKWVIPCNWKFAAEQFCSDMYHAGTMSHLSGVLAGLPPEMDLTQIQLSKNGNQFRSAWGGHGAGWFINDSSILLSVVGPKITQYWTQGPAAEKAARRVPQLPILDMFGQHMTVFPTCSFLPGINTIRTWHPRGPNEVEVWAFVLVDADAPEDIKEEFRLQNIRTFNAGGVFEQDDGENWVEIQRVMRGHKAKSTSLCAKMGLNVPNKNNPAYPGKTAYVYAEEAARGMYHHWSRMMSEPSWDTLKP
What are the official names of this protein?
Biphenyl dioxygenase subunit alpha, Biphenyl 2,3-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.
Protein: APAH_AERS4
Sequence: MANCFVGDIQGCYDDLRRLLDLAKFDPAKDVLWLCGDLVARGPDSLKTLRYVKSLGQRAVTVLGNHDLHLLAVADGVAPLKKKDKLQALMEAPDRDELLTWLRHRPLLAEHPDLPIMMVHAGISPAWDARTARNCAREVESLLRGDQYSWLLHNMYGDLPDGWSEDLAGIERYRYIINTFTRMRFCYFDGRLEFKCKKGPTESTPGLRPWFEQREHHMDDPILVFGHWAALMGNTGRNDIKALDTGCVWGNSLTLWRYEDDALIATPCPTHAK
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: NRAM_I83A6
Sequence: MNPNQKIITIGSVSLTIATVCFLMQIAILATNVTLHFRQNERSIPAYNQTTPCKPIIIERNIKYRNWSKPQCQITGFAPFSKDNSIRLSAGGGIWVTREPYVSCDPSKCYQFALGQGTTLDNNHSNGTIHDRTPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCVTGDDRNATASFIYNGMLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGKADIRILFIREGKIVHISPLSGSAQHIEECSCYPRYPNVRCVCRDNWKGSNRPVIDINMADYSIDSSYVCSGLVGDTPRNDDSSSSSNCRDPNNERGNPGVKGWAFDIGDDVWMGRTISKDSRSGYETFRVIGGWATANSKSQTNRQVIVDNNNWSGYSGIFSVESKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPL
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: NR5A2_RAT
Sequence: MSASSITGDFQDFLKHGLPAIAPAPGSETPHSPKLEEKHREKRAGLPDRHRRPIPARSRLVMLPKVETEASGLVRSHGEQGQMPENMQVSQFKMVNYSYDEDLEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNQKRYTCIENQNCQIDKTQRKRCPYCRFKKCIDVGMKLEAVRADRMRGGRNKFGPMYKRDRALKQQKKALIRANGLKLEAMSQVIQAMPSDLTSAIQNIHSASKGLPLSHVALPPTDYDRSPFVTSPISMTMPPHGSLHGYQPYGHFPNRAIKSEYPDPYSSSPESMMGYSYMDGYQTSSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQNNRNRQEKLSAFGLLCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVAHGKEGTIFLVTGEHVDYSSIISNTEVAFNNLLSLAQELVVRLRSLQFDQREFVCLKFLVLFSSDVKNLENFQLVEGVQEQVNAALLDYTLCNYPQQTEKFGQLLLRLPEIRAISKQAEDYLYYKHVNGDVPYNNLLIEMLHAKRA
What is the function of this protein?
Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis.  Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism.  Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex.  Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver.  May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development (By similarity).  Activates the transcription of CYP2C38 (By similarity).
What are the official names of this protein?
Nuclear receptor subfamily 5 group A member 2, FTZ-F1 beta, Liver receptor homolog 1, LRH-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR5 subfamily.
What are the subcellular locations of this protein?
Nucleus.