PharMolix/UniProtQA huggingface dataset:
Protein: SNX4_YEAST
Sequence: MTDKGKNDLTSKAKDKARGNPEKPPYWFEIIVSDPQKRTGDPGSSSGYVSYQISTKTNNTSFYDNRGDPESIIVVHRRYSDLLLLHDILLNRFPTCIIPPLPDKKVFQYIAGDRFSQRFTQKRCHSLQNFLRRVSLHPDLSQSKVFKTFLVSKDWESHRKVLQDSLQPNKDEVTDAFMNAFKTVHKQNEEFTEIREKSDKLDRTVTKIDKLFHKVVKKNDSMSEDYTKLGSNLQELQELVTGENEELAAKLKIFNEGVTQLSYGLQDLTKYLDYEYIVDLKDLEHYIDSMRQLIKLKDQKQIDYEELSDYLTRSIKEKNNLISGYGGSNFFANKLEELAGINQEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKEIDHFESVKTAEIKKSLGSLADHHIEFYERILEAWEKVDDSL
What is the function of this protein?
Sorting nexin, involved in the separation or division of vacuoles throughout the entire life cycle of the cells (PubMed:12048214, PubMed:12554655, PubMed:15800066, PubMed:17420293, PubMed:18818209, PubMed:19793921, PubMed:20729555, PubMed:20861302, PubMed:21429936, PubMed:8663607).  Involved in retrieval of late-Golgi SNAREs from post-Golgi endosomes to the trans-Golgi network, for cytoplasm to vacuole transport (Cvt), autophagy, mitophagy, and pexophagy (PubMed:12048214, PubMed:12554655, PubMed:15800066, PubMed:17420293, PubMed:18818209, PubMed:19793921, PubMed:20729555, PubMed:20861302, PubMed:21429936, PubMed:8663607).  Involved in proper sorting of the v-SNARE protein SNC1 (PubMed:12554655).
What are the official names of this protein?
Sorting nexin-4, Autophagy-related protein 24, Cytoplasm to vacuole targeting protein 13.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Preautophagosomal structure membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Endosome and other perivacuolar punctate structures (PubMed:17420293). Associates to phosphatidylinositol 3-phosphate, necessary for peripheral membrane localization to the perivacuolar punctate structures (PubMed:12048214).
Protein: RIMM_RIPO1
Sequence: MDNSESWLEIGRIVAAQGLKGELKVMSSSDFPERFEKPGTRWLQSPDRLSIQEVELVRGRYVPGKNLYVIKLAEIADRTQAETLRDYTLLVPSSDRPQLNEGEYHVSDLINLTVYHQQTGEEIGVVTDMLSAGNDLLEVQLNTLNSSENTSSKKVLIPFVYEIVPVVDLVNKRIEINPPVGLLELS
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_FERNB
Sequence: MITIEDLKPTPGSNKKYKRLGRGQGSGKGKTAGKGHKGQKSRGTGKVRAWMEGGQTPLHRRLPKFGFKNFTKKFYAVVNLETLEEKFDSNAVVTPEVLIEKGIIDKIYDGVKILARGEITKPLTVKAHKFSEKAKEKIEKVGGKIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SYH_DESRM
Sequence: MLTTRPRGTNDILPGEVEKWQFLEQLTRQVCREYGYGEIRTPIFEHTELFARGVGETTDIVEKEMYTFTDRGDRSITLRPEGTASTVRAYVENKLHALPQPVKLYYTGPMFRYDRPQAGRYRQFHQFGVEVFGSNDPAIDAEVIAMAMDIYHRIGLQNLKLHINSVGCPECRPVLRQRLQEYFKPHLSNLCSNCQGRYERNPLRILDCKSEKCQEIGQSAPTTLDVLCPECNSHFESVKTYLDAVGVSYIIDNRLVRGLDYYTRTAFEIMTQDIGAQSSIGGGGRYNGLIEECGGPATPGIGFALGLERILLTAERQGITFPITRGPQVYIATVGSGIERQAFALLQDLRRQGIAAEKDYLGRSLKAQMKFAGKLDTRFVVILGEEEFDRGVAVVRDMQAGEQQEVSLRELVLFIKART
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_SALAR
Sequence: MKICLLDETGAGDGALSVLAARWGLEHDENNLMALVLTPQHLELRKRDEPKLGGIFVDFLGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADADIGPWLRQRLQLIHASSLTALTDITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPLADIATPNAIVTKGHRFDIYAGTA
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIRC2_HUMAN
Sequence: MGSRWSSEEERQPLLGPGLGPGLGASWRSREAAAAALPAAVPGPGRVYGRRWLVLLLFSLLAFVQGLVWNTWGPIQNSARQAYGFSSWDIALLVLWGPIGFLPCFAFMWLLDKRGLRITVLLTSFLMVLGTGLRCIPISDLILKRRLIHGGQMLNGLAGPTVMNAAPFLSTTWFSADERATATAIASMLSYLGGACAFLVGPLVVPAPNGTSPLLAAESSRAHIKDRIEAVLYAEFGVVCLIFSATLAYFPPRPPLPPSVAAASQRLSYRRSVCRLLSNFRFLMIALAYAIPLGVFAGWSGVLDLILTPAHVSQVDAGWIGFWSIVGGCVVGIAMARFADFIRGMLKLILLLLFSGATLSSTWFTLTCLNSITHLPLTTVTLYASCILLGVFLNSSVPIFFELFVETVYPVPEGITCGVVTFLSNMFMGVLLFFLTFYHTELSWFNWCLPGSCLLSLLLILCFRESYDRLYLDVVVSV
What is the function of this protein?
Electrogenic metabolite transporter.
What are the official names of this protein?
Solute carrier family 49 member 4, Disrupted in renal cancer protein 2, Disrupted in renal carcinoma protein 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: KDPC_CLOBB
Sequence: MKEFKAVFPKALIIFMIFTILCGGIYTIFITGISQLIFPKQANGSIIEVNGKKYGSVLLAQQYNDEKHLWGRIMNIDTDTFVDDNGKKLAYSAPSNLSPASKEYEALVKERVDKIKANHPEQDDKAIPVDLVTCSGSGLDPHISVAAAKYQVNRIAKNNNMKIKDVEKIIDKYTSGKLFGVLGEKTVNVLEVNLAIDGILK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FRDC_SALPK
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKHGAESWMGFVGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKGLWVVTAVVTVVILYVALFW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METK_MYCBT
Sequence: MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNVPVQLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV_HV1M2
Sequence: MRVREMQRNWQHLGRWGLLFLGILIICSAADKLWVTVYYGVPVWKEATTTLFCASDAKAYEREVHNVWATYACVPTDPSPQELVLGNVSEKFNMWKNNMVDQMHEDIISLWDESLKPCVKLTPLCVTLNCTKAIINVTSSNNTTLAPNVTISEEMKNCSFNITTEIRDKQKKEYALFYKLDVVQINNSNTSYRLINCNTSTLTQACPKVSFDPIPIHYCAPAGFAILKCNNKTFNGTGLCRNVSTVQCTHGIKPVVSTQLLLNGSLAEEKMIIRSENISDNTKTIIVQFKNPVKINCTRPNNNTRRSIHIGPGRAFYATGEIIGDTRKAHCNISEKQWYDTLIKIATEFKDQYNKTVGFQPSAGGDLEITTHSFNCRGEFFYCNTTILFNHTRVNDILSNNHTRENDTITLPCRIKQIVNMWQRVGQAMYAPPIAGKIQCNSNITGLLLTIDGGEGNESETLRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRQVVQREKRAVGMGAMFLGFLGAAGSTMGAASITLTVQARNLLSGIVQQQSNLLKAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKLICPTTVPWNLSWSNKSQDEIWGNMTWMEWEKEIGNYTDTIYRLIESAQNQQEKNEQDLLALDKWDNLWNWFSITRWLWYIEIFIMIIGSLIGLRIVFTVLSIINRVRQGYSPLSLQTLIPNSRGPERPGGIEEEGGEQDKDRSIRLVSGFLALAWDDFRSLCVFSYHCLRNFILIAARTVDKGLKRGWEVLKYLWNLAQYWGQELKNSAISLLDRTAIAVAEGTDRIIEILQRAGRAVLNIPRRIRQGLERALL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: ENTP6_MOUSE
Sequence: MRKIPNHGTLRMTKVAYPLGLCVGLFIYVAYIKWHRASAAQAFFTIAGAASGARWTQQAFSSPGSAARGHEVFYGIMFDAGSTGTRIHVFQFARPPGETPTLTHETFKALKPGLSAYADDVEKSAQGIQELLNVAKQHIPYDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDEGVSAWITVNFLTGSLKTPGSSSVGMLDLGGGSTQITFLPRVEGTLQASPPGHLTALQMFNRTYKLYSYSYLGLGLMSARLAILGGVEGKPAENDKELVSPCLSPRFRGEWEHAEVTYRISGQKAVGLYELCASRVSEVLRNKVHRTEEAQHVDFYAFSYYYDLAASFGLIDAEKGGSLVVGDFEIAAKYVCRTLETQPPSSPFACMDLTYISLLLHEFGFPGDKVLKLARKIDNVETSWALGAIFHYIDSLKRQKVPAL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner.  Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP.  The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 6, NTPDase 6, CD39 antigen-like 2.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Cell membrane; Single-pass type II membrane protein. Note=Exists as a secreted and membrane-bound forms in the medium of transfected cells, the secreted form is predominant.
Protein: SYDND_RALSO
Sequence: MRTQYCGQVTEQLLGQSVTLSGWAHRRRDHGGVIFIDLRDREGLVQVVCDPDRPEMFKVAEGVRNEFCLQVKGIVRARPEGTTNPNLASGKIEVLCHELTVLNASVTPPFQLDDDNLSETTRLTHRVLDLRRPQMQYNLRLRYKVAMEVRKYLDDKGFIDIETPMLTKSTPEGARDYLVPSRVNAGQFFALPQSPQLFKQMLMVSGFDRYYQITKCFRDEDLRADRQPEFTQIDCETSFLSEQEIRDLFEEMIRTVFQNTMSVALDAKFPVMEFREAMARFGSDKPDLRVKLEFTELTDAMKDVDFKVFSGPANAEGGRVVALRVPGGAALSRGDIDAYTKFVEIYGAKGLAWIKVNEVAKGRDGLQSPIVKNLHDAAIAEILKRSGAQDGDILFFGADRAKVVNDAMGALRLKVGHSDFAKSTGLFEDAWKPLWVVDFPMFEYDEEDARWVAMHHPFTSPKDEHLEYLETDPGKCIAKAYDMVLNGWEIGGGSVRIYREEVQSKVFRALKIGDEEARAKFGFLLDALQYGAPPHGGIAFGLDRVVTMMAGADSIRDVIAFPKTQRAQDLLTQAPSPVDEKQLRELHIRLRAAEAKVAAPAAATA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_ECOLU
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MIC27_YEAS2
Sequence: MVNFYDDVDESKSHGEFPLIPVVLQNSSELSVRTIPTGNEIIESVHLTKWLRKYRNALASQLDRYEKGWQSKIANFRLQVQHVINYSRKNIFNVDSENKHTVVPGSLIALGAFFAGSIAVNRSNWGAKRLIFGHKSSILEKLCTSLPSRILLPWVLAAATFKYWAPQTSQNLVNATENDLLPADFVKSYHNTWKRIYEEGYVAKKCDLKRQIDQTLQKNIRYAREQLYEKLEQA
What is the function of this protein?
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
What are the official names of this protein?
MICOS complex subunit MIC27.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YER5_YEAST
Sequence: MNFKEPLVNFLKCVLNNINSAFSHRIDQLQLQLLRETNILRVLNRGIERLFSENPRTHSVSRIVVEKDVGCRIGRYVEGSKYELVESRAKEIQIYYERMVFEITQELKGDKRVFALIANLSQRYSAERKEIRNVKVHGGRPCNENEFQVIPIRFKPINLERRARLIRKKKTIN
What are the official names of this protein?
Uncharacterized protein YER085C.
Protein: RL34_NITEU
Sequence: MKRTYQPSVISRKRTHGFRVRMKTRGGRAVIRARRAKGRAKLSV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RS3A_NEOFI
Sequence: MAVGKNKRLSKGKKGVKKRTVDPFSRKDEYSVKAPSTFQIRDVGKTLVNRTSGLKNANDSLKGRIFEVSLADLQNDEDHAFRKVKLRVDEVQGKNCLTNFHGLDFTTDKLRSLVRKWQSLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYARSSQIRAIRKKMIEIMQREAASCSLAQLTHKLIPEVIGREIEKATQGIYPLQNVHIRKVKLLKAPKFDLGALLNLHGESTTDDKGHKVEREFKEQVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_NICSY
Sequence: MGLPWYRVHTVVLNDPGRLLSVHIMHTALVAGWAGSMALYELAVFDPSDPVLDPMWRQGMFVIPFMTRLGITNSWGGWSITGGTVTNPGIWSYEGVAGAHIVFSGLCFLAAIWHWVYWDLEIFCDERTGKPSLDLPKIFGIHLFLSGVACFGFGAFHVTGLYGPGIWVSDPYGLTGKVQPVNPAWGVEGFDPFVPGGIASHHIAAGTLGILAGLFHLSVRPPQRLYKGLRMGNIETVLSSSIAAVFFAAFVVAGTMWYGSATTPIELFGPTRYQWDQGYFQQEIYRRVSAGLAENQSLSEAWSKIPEKLAFYDYIGNNPAKGGLFRAGSMDNGDGIAVGWLGHPIFRDKEGRELFVRRMPTFFETFPVVLVDGDGIVRADVPFRRAESKYSVEQVGVTVEFYGGELNGVSYSDPATVKKYARRAQLGEIFELDRATLKSDGVFRSSPRGWFTFGHASFALLFFFGHIWHGARTLFRDVFAGIDPDLDAQVEFGAFQKLGDPTTKRQAA
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: THIL_NITMS
Sequence: MSKLDESEIIKIFQRKLGNKNSEDVEIFKLKQNIIAKTDTLVQSTDIPPKMKLGEAARKSVVACVSDFAAKGVKPQYGIISINFPSNISRSKVEEAATGFRKACSEFGISILGGDTNAGKEIVFNVCLFGSAEKIVPRNGSESKDLIFATGPFGYTGAGLSILLYKKKGKREFVAKAIKAVTHPKPRVDFGVKNKRYFTSSMDSSDGLSTTLNEMAKQSKKKFVINNSPHKKDLGEFAKSNQDNLVFHGGEEYEFVFTINPKHKKTILKNAKSLRTPIIEIGYVTTGKGVILQRDNKDIPLKDKGWKHFR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: H1_ONCMY
Sequence: MAEVAPAPAAAAPAKAPKKKAAAKPKKAGPSVGELIVKAVSASKERSGVSLAALKKSLAAGGYDVEKNNSRVKIAVKSLVTKGTLVQTKGTGASGSFKLNKKAVEAKKPAKKAAAPKAKKVAAKKPAAAKKPKKVAAKKAVAAKKSPKKAKKPATPKKAAKSPKKVKKPAAAAKKAAKSPKKATKAAKPKAAKPKAAKAKKAAPKKK
What is the function of this protein?
Oncorhyncin II has antibacterial activity against Gram-positive and Gram-negative bacteria at submicromolar concentrations.  Potentially important role in mucosal defense.
What are the official names of this protein?
Histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. SUBCELLULAR LOCATION: [Oncorhyncin II]: Secreted.
Protein: PRSA1_LACPL
Sequence: MKKWLIALAGVLLTFTLAGCGSKTVASTSGGKITESQYYSSMKGTSSGKQVLQQMILNKVLEKDYGSKVSTKQVTKQYNTYKSQYGSSFSTVLSQNGLTTKTFKEQLRSNLLLKEAVKDKVKITDKALKKQWKSYEPKVTVQHILVAKSATADKVLDALKKDSSQANFTKLAKKYSTDTTTKNDGGKLSAFDNTNTSYSSKFLTAAFKLKNGEYTTSAVKTSNGYEIIRMIKNPGKGKMSDHTADLKKQIWDNDMSDSTVLQNVVSKVLKGGNVSIKDNDLKDILSSYLSTSSSSSSN
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 1.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: M2OM_DICDI
Sequence: MSSFNTQNKNVLQTPIPAPTPQSQLKQFVIGGLAGMLSSAFTHPIDSLKVRMQLQGEGTGVGPKRGALKMLVHINQTEGFFTLYKGLSASLLRQATYTTTRFGLYDLIKDIVAKDDKPLPFTQKIMVGMLSGAGGAIVGTPADLTMVRMQADGKLPFNLRRNYKNVFDGIFRISKEEGIISLWKGCSPNLIRAMFMTAGQVSSYDQTKQLMLASGYFHDDIKTHLIASTTAAFVAAVATSPLDVIKTRIMNSPKTVTGELQYKGTFDCLSKTLRAEGFKAFYKGFNPYFMRLGPQTILTFIFVEQLNILWKKSQSYFK
What is the function of this protein?
Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane.  Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity).
What are the official names of this protein?
Probable mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, Mitochondrial substrate carrier family protein ucpC, Solute carrier family 25 member 11 homolog.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ULAR_ECO24
Sequence: MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_YERPS
Sequence: MIRILLSNDDGISAPGIQTLASALREFAQVQIVAPDRNRSGASNALTLDSALRITTLSNGDIAVQQGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGYPALAVSLNGHQHYDTAAAVTCRLLRALQRKPLRTGKILNINVPDLPLSEIKGIRVTRCGSRHPAEQVFCQQDPRGQDLYWIGPPGEKYDAGPDTDFAAVEQGYVSITPLQVDLTAYTAQEVVESWLANTEVDGEW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_STRA1
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTRETVTAYREYKQVIQNISDAEEMIKDASGDAELEEMAKEELKESKAAKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYEIDQKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKMDEVIDALVMYDQTQKLEALNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.