PharMolix/UniProtQA huggingface dataset:
Protein: HBB_ANAPL
Sequence: MVHWTAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFASFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFTKDFTPECQAAWQKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RD23A_MOUSE
Sequence: MAVTITLKTLQQQTFKIRMEPDETVKVLKEKIEAEKGRDAFPVAGQKLIYAGKILSDDVPIKEYHIDEKNFVVVMVTKAKAGQGIPAPPEASPTAVPEPSTPFPPVLASGMSHPPPTSREDKSPSEESTTTTSPESISGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERVVAALRASYNNPHRAVEYLLTGIPGSPEPEHGSVQESQAPEQPATEAAGENPLEFLRDQPQFQNMRQVIQQNPALLPALLQQLGQENPQLLQQISRHQEQFIQMLNEPPGELADISDVEGEVGAIGEEAPQMNYIQVTPQEKEAIERLKALGFPESLVIQAYFACEKNENLAANFLLSQNFDDE
What is the function of this protein?
Involved in nucleotide excision repair and is thought to be functional equivalent for Rad23b in global genome nucleotide excision repair (GG-NER) by association with Xpc.  In vitro, the XPC:RAD23A dimer has NER activity.  Can stabilize Xpc.  Reported differences to Rad23b in regard to NER activity and Xpc stabilization are probably due to differences in expression levels with Rad23a being much less expressed than Rad23b.
What are the official names of this protein?
UV excision repair protein RAD23 homolog A, HR23A, mHR23A.
What is the protein family that this protein belongs to?
Belongs to the RAD23 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUON1_KORVE
Sequence: MTSLPNLLSRSDYLLALPMLVLSGFAVAILLLDLVLPKGWKRWNAALALAGLAAATMSLAKVWQAVYYIETPESKRFSGFLGSLVMDRFAIYFYLLFIVGAAVAILMSIRYMEIEHEDHGEYHALILFATIGMMCMASGMDLILLFVGLELMALSTYVLVGFLKRDKRSNEAALKYLLLGAFSSGIFAYGLSLFYGLTGSTNLTEIANKLAQRMADNPRDPIALLALITTATGLLFKIAAVPFHQWAPDAYEGAPTAVTGFMSVAVKAAGWAMLLRIFLFMLWPMREQYTPILIFVAVATMIGGNFAALTQTNVKRLLAYSSISHVGYMLLGLVASDGKNSSTGIKGILVYLAVYTFMNLGAFAVITSLRRRDIIGDELDDLAGLFFKAPSEAVLLLVFLLSLAGIPPLAGFWGKYYIFLSLMETGHYTLAVVAVLFAVLGMYYYLRIANAAFMREAVDAEPVKISPSLGAALWISALGTLGIGLFPEVFLRIVNWSLALSGDARVIGLLR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 1, NADH dehydrogenase I subunit N 1, NDH-1 subunit N 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: JMT_BRARP
Sequence: MEVMRILHMNKGNGETSYAKNSIVQSNIISLGRRVMDEALKKLMIRNSEILSFGIADLGCSSGPNSLLSISNIVETIQNLCHDLDRPVPELSLSLNDLPSNDFNYIFASLPEFYDRVKKRDNNYESLGFEHGSGGPCFVSAVPGSFYGRLFPRRSLHFVHSSSSLHWLSQVPCGEVNKKDGVVITADLDNRGKIYLSKTSPKSAHKVYALQFQTDFSVFLRSRSEELVPGGRMVLSFLGRSSPDPTTEESCYQWELLAQALMSLAKEGIIEEENIDAFNAPYYAASPEELKMAIEKEGSFSIDRLEISPVDWEGGSISDDSYDIVRFKPEALASGRRVAKTIRAVVEPMLEPTFGQKVMDELFERYAKLVGEYVYVSSPRYTIVIVSLLRMG
What is the function of this protein?
Catalyzes the methylation of jasmonate into methyljasmonate, a plant volatile that acts as an important cellular regulator mediating diverse developmental processes and defense responses.
What are the official names of this protein?
Jasmonate O-methyltransferase, Floral nectary-specific protein 1, S-adenosyl-L-methionine:jasmonic acid carboxyl methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic (PubMed:10809010). Partially nuclear (PubMed:10809010).
Protein: RTP1_MACFA
Sequence: MRIFRPWRLRCPALHLPSLSVFPLRWKLPSLTTDKTMCKSVTTDEWKKVFYEKMEEAKPADSWDLIIDPNLKHNVLSPGWKQYVELHASGRFHCSWCWHTWQSPHLVILFHMFLDRAQRAGSVRMRVFKQLCYECGSARLDESSMLEENIEGLVDNLITSLREQCYGERGGQYRIHVASRQDNRRHRGEFCEACQEGIVHWKPSEKLLEEEATTYTFSRAPSPTKPQDETGSGWNFCSIPWCLFWATVLLLIIYLQLSFRSSV
What is the function of this protein?
Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs.
What are the official names of this protein?
Receptor-transporting protein 1.
What is the protein family that this protein belongs to?
Belongs to the TMEM7 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein. Note=Effective cell surface expression depends upon interaction with olfactory receptors.
Protein: RES_CLOPF
Sequence: MLVGYARVSTEEQSLNRQIDMLVDYGVDKRNIYQEKISGMKPNREQLDKMIDELQEGDTVIITDLTRISRSTKDLLNIIDRIKAKGASIKSIKDTWLDTSSDNPYNSFLLTVMSGLSQLERDLISQRTKEGLKSAKARGRNGGRPSKRNDKADTVGLLYREGYKIVDIVKQTGLSRATVYRVLNDLKLK
What is the function of this protein?
A likely role for the res protein would be to stabilize pIP404 by reducing the number of plasmid multimers resulting from homologous recombination.
What are the official names of this protein?
Resolvase.
What is the protein family that this protein belongs to?
Belongs to the site-specific recombinase resolvase family.
Protein: F16A2_NITHX
Sequence: MSHELTLQQRLEVQAGPDPLHRAVKEAVAALAQAAIDISDLTCRGALAGITGEAQGRNTDGDIQKDLDVRADQIIRDALSALPIAVLASEEMAELDILNPGAPISVAFDPLDGSSNINTNISVGTIFSIMPTPPDASAAFTQPGSAQLAAGFVVYGPQTSLILTLGQGVDIFTLDRVERVFKLTGSMMQIPADATEFAINTSNRRHWDLPVRAYIDECLMGADGPSGKNFNMRWIGSLVAEAFRILVRGGIFLYPGDARDGYEDGRLRLVYEAHPMAFIIEQAGGGASTGRKRILDIVPGSLHQRVPLIMGSIKNVRRLEDMHTGPNVALEANAPLFGHRGLFRV
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 2, FBPase class 1 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLN1A_MYCS2
Sequence: MDRQKEFVLRTLEERDIRFVRLWFTDVLGYLKSVAIAPAELEGAFEEGIGFDGSSIEGFARVFESDTVARPDPSTFQVLPWKTSDGNHYSARMFCDITMPDGSPSWADSRHVLRRQLAKASDLGFTCYVHPEIEFFLLKPGPNDGTPPEPADNGGYFDQAVHDAAPNFRRHAIEALEQMGISVEFSHHEGAPGQQEIDLRYADALSMADNVMTFRYLVKEVALADGVRASFMPKPFAEHPGSAMHTHMSLFEGDTNAFHSPDDPLQLSDVAKSFIAGILEHANEISAVTNQWVNSYKRLVHGGEAPTAASWGAANRSALVRVPMYTPHKVSSRRVEVRSPDSACNPYLTFAVLLAAGLRGVEKGYVLGPQAEDNVWSLTQEERRAMGYRELPTSLGNALESMENSELVAEALGEHVFDYFLRNKRSEWENYRSHVTPYELKNYLSL
What is the function of this protein?
Glutamine synthetase (GS) is an unusual multitasking protein that functions as an enzyme, a transcription coregulator, and a chaperone in ammonium assimilation and in the regulation of genes involved in nitrogen metabolism.  It catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.  Feedback-inhibited GlnA also interacts with and regulates the activity of the transcriptional regulator TnrA.  During nitrogen limitation, TnrA is in its DNA-binding active state and turns on the transcription of genes required for nitrogen assimilation.  Under conditions of nitrogen excess, feedback-inhibited GlnA forms a stable complex with TnrA, which inhibits its DNA-binding activity.  In contrast, feedback-inhibited GlnA acts as a chaperone to stabilize the DNA-binding activity of GlnR, which represses the transcription of nitrogen assimilation genes.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_CYAP4
Sequence: MPTIQQLIRSERQELKKKTKSPALKSCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGIGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDTAGVKDRKQGRSKYGAKRPKPGAASTASTGKKR
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: IDI2_PARZE
Sequence: MTDSKDHHVAGRKLDHLRALDDDADIDRGDSGFDRIALTHRALPEVDFDAIDTATSFLGRELSFPLLISSMTGGTGEEIERINRNLAAGAEEARVAMAVGSQRVMFTDPSARASFDLRAHAPTVPLLANIGAVQLNMGLGLKECLAAIEVLQADGLYLHLNPLQEAVQPEGDRDFADLGSKIAAIARDVPVPVLLKEVGCGLSAADIAIGLRAGIRHFDVAGRGGTSWSRIEYRRRQRADDDLGLVFQDWGLQTVDALREARPALAAHDGTSVLIASGGIRNGVDMAKCVILGADMCGVAAPLLKAAQNSREAVVSAIRKLHLEFRTAMFLLGCGTLADLKDNSSLIRQ
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUD_PSESP
Sequence: MSLNIFWFLPTHGDGKYLGTSDGARAVDHGYLQQIAQAADRLGFGGVLIPTGRSCEDSWLVAASLIPVTERLKFLVALRPGIISPTVAARQAATLDRLSNGRALFNLVTGGDPDELAGDGLHLNHQERYEASVEFTRIWRKVLEGENVDYDGKHIQVKGAKLLYPPVQQPRPPLYFGGSSEAAQDLAAEQVELYLTWGEPPAAVAEKIAQVREKAAAQGREVRFGIRLHVIVRETNEEAWAAADRLISHLDDDTIARAQASLARFDSVGQQRMAALHGGNRDNLEVSPNLWAGVGLVRGGAGTALVGDGPTVAARVKEYADLGIDTFIFSGYPHLEESYRVAELLFLHIDVQRPEQPKTGGYVSPFGEMVANDILPKSVSQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: SYS2_METBU
Sequence: MELKFNLKGAFKTSTDPTGAKEVIAQYFDEANNTILKKGAPEGQGAKITQWDIVDGSIELTIESGRYVRAHDAIMRLKKPLAAKLGKEFRIGIRGVDVKKFTISMPAEGEIGNMNIPHVSNISKVEGGLILELNVGESELERRIPDRILTLMEEKVRAKDYGGKAEHWQILWESDKKEHTFAGDPTQEMMKHGWIKRGASRGQWIHGPQSTKMFRTFEKIVYDELLEPLGYREMIFPKLVPWEVWQKSGHAKGVYPEIYYVCPPKTRDPAYWEEVSDHYKVTHEVPTELIKSKIGDPIGGLCYAQCPPFWMYLQGETIPTDEFPIKVFDKSGTSHRYESGGIHGIERVDEFHRVEIVWLGTKEQVIETARKLHERYMHIFNEILDLEWRKAWVTPWFMAQEGLTGLSEQGEAGTTDYEAPLPYRGDDGEWLEFQNVSINGNKYPSGFNVKSQTGEELWSGCSGVGLERWASAFFAQKGLDPENWPEEFRKRVGEVPKGIRFL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Type-2 serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_XYLFA
Sequence: MTGLFQLVSSYSPSGDQPTAVQKLVTNFHAGIAKQVLLGVTGSGKTYTIANVVEQIQKPTLVMAPNKTLAAQLYGEFKAFFPHNAVEYFVSYYDYYQPEAYVPASDTFIEKDSSINEYIEQMRLAATKALLSRSDVLVVATVSAIYGLGAPEDYLSLRLILSLGEHIEQRQLIRHLTELQYTRNELDLVRGSFRVRGEVVDVFPAESEMEALRIELFDGEIESLSLFDPLTGQTVRKLQRYSVYPKTHYATTRERTLSAVDTIKDELKEYLELLYGRNKLVEAQRLAQRTQFDLEMMAEVGYCNGIENYSRHLTGKAPGEPPPTLFDYLPPDALLVIDESHVTIPQIGAMFKGDRSRKETLVEFGFRLPSALDNRPLRFEEWEVRSPRSIYVSATPGSYEFRESAGEVIELLVRPTGLIDPEIEIRPVATQVDDLISQINVCIKLGDRVLVTTLTKRMAENLTEYLSEQGIRIRYLHSEIDTVERVEIIRDLRLGKFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSTSSLIQTIGRAARSVRGRAILYADKVTRSMRAAIDETERRRQKQKEYNAENGIVPKSVVRPISDILEGARDGVEVKSKGKGRRVDEVPADYCALNQAEIAAQMKVLEQQMYQHARDLEFEDAARIRDQIQRLREAGLG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_RHOCS
Sequence: MAEISAALVKELREKTGAGMMDCKKALTETSGDMEAAVDWLRKKGLAAAAKKSGRVAAEGLVGVVAAPTAGACVEVNAETDFVARNETFQNFVAKVTELALTTGDDVEKLQSQPFPGTGRTVAEELTHLVATIGENMTIRRAARLSVTQGIVSTYMHSSLVPNLGKIGVLVALESAGDQAKLQELGKQIAMHIAAARPEALDIADVDPSKLNRERDVLADQARASGKPEEIVQKMVEGRVRKYYEEVVLLEQVFVVDGETKIRKVVENAGKTVGAPVKLTGFVRFALGEGIEKATSDFAAEVASMAG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR13_GRATL
Sequence: MTRIVGVDLPKNKRIEISLTYIYGIGKSKAIEILEQLKINRNIKTKELKDEQIVLIRQILNNSYQIEGDLKRVESMNIKRLMTISSYRGKRHQLGLPLRGQNTRTNARTKRGIKKTMAGKKKAPRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.
What are the official names of this protein?
30S ribosomal protein S13, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: QUEF_SHEB2
Sequence: MTQNHDPYSDAQALVGLTLGKATDYQAEYDASLLQGVPRSLNRNAIALTGTLPFHGADIWTGYELSWLNAKGKPMVAIAEFHLSYESLNLIESKSFKLYLNSFNQTKFDSIDSLQKTLVADLSQCAQGDISVKIIEPKSFGIQRIIELPGTCIDDLDIEVSDYSFNPDYLENSTDDKQTVAETLNSNLLKSNCLITSQPDWGSVMIRYQGPKIDREKLLRYLISFRQHNEFHEQCVERIFVDLKRFCHCTKLTVYARYTRRGGLDINPYRSDFEQPGESHRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_ECOSE
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: TCAF2_HUMAN
Sequence: MATIAAAAFEALMDGVTCWDVPRGPIPSELLLIGEAAFPVMVNDKGQVLIAASSYGRGRLVVVSHEGYLSHTGLAPFLLNAVSWLCPCPGAPVGVHPSLAPLVNILQDAGLEAQVKPEPGEPLGVYCINAYNDTLTATLIQFVKHGGGLLIGGQAWYWASQHGPDKVLSRFPGNKVTSVAGVYFTDTYGDRDRFKVSKKVPKIPLHVRYGEDVRQDQQQLLEGISELDIRTGGVPSQLLVHGALAFPLGLDASLNCFLAAAHYGRGRVVLAAHECLLCAPKMGPFLLNAVRWLARGQTGKVGVNTNLKDLCPLLSEHGLQCSLEPHLNSDLCVYCCKAYSDKEAKQLQEFVAEGGGLLIGGQAWWWASQNPGHCPLAGFPGNIILNCFGLSILPQTLKAGCFPVPTPEMRSYHFRKALSQFQAILNHENGNLEKSCLAKLRVDGAAFLQIPAEGVPAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGTWTCSSSLYPSKHPITVEINGINPGNNDCWVSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKARKLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYKLGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDPEPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQRHGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDWNVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPKDNTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASLPEWQENPMQVYLRARK
What is the function of this protein?
Negatively regulates the plasma membrane cation channel TRPM8 activity.  Involved in the recruitment of TRPM8 to the cell surface.  Promotes prostate cancer cell migration stimulation in a TRPM8-dependent manner.
What are the official names of this protein?
TRPM8 channel-associated factor 2, TRP channel-associated factor 2.
What is the protein family that this protein belongs to?
Belongs to the TCAF family.
What are the subcellular locations of this protein?
[Isoform 2]: Cell membrane. Note=Colocalizes with TRPM8 on the plasma membrane.
Protein: CRH1_YEAST
Sequence: MKVLDLLTVLSASSLLSTFAAAESTATADSTTAASSTASCNPLKTTGCTPDTALATSFSEDFSSSSKWFTDLKHAGEIKYGSDGLSMTLAKRYDNPSLKSNFYIMYGKLEVILKAANGTGIVSSFYLQSDDLDEIDIEWVGGDNTQFQSNFFSKGDTTTYDRGEFHGVDTPTDKFHNYTLDWAMDKTTWYLDGESVRVLSNTSSEGYPQSPMYLMMGIWAGGDPDNAAGTIEWAGGETNYNDAPFTMYIEKVIVTDYSTGKKYTYGDQSGSWESIEADGGSIYGRYDQAQEDFAVLANGGSISSSSTSSSTVSSSASSTVSSSVSSTVSSSASSTVSSSVSSTVSSSSSVSSSSSTSPSSSTATSSKTLASSSVTTSSSISSFEKQSSSSSKKTVASSSTSESIISSTKTPATVSSTTRSTVAPTTQQSSVSSDSPVQDKGGVATSSNDVTSSTTQISSKYTSTIQSSSSEASSTNSVQISNGADLAQSLPREGKLFSVLVALLALL
What is the function of this protein?
Probable glycosidase that plays a role in cell wall architecture.  Required for the transfer of chitin to 1,6-beta-glucan in the cell wall.
What are the official names of this protein?
Probable glycosidase CRH1, Congo red hypersensitive protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. CRH1 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Lipid-anchor, GPI- anchor. Note=Covalently-linked GPI-modified cell wall protein (GPI- CWP), localized particularly in chitin-rich areas. Found at the incipient bud site, around the septum area in later stages of budding, and in ascospore envelopes. Redistributes uniformly over the cell cortex upon heat stress.
Protein: ELOF1_ARATH
Sequence: MGKRKSRAKPAPTKRMDKLDTIFSCPFCNHGSSVECIIDMKHLIGKAACRICEESFSTTITALTEAIDIYSEWIDECERVNTAEDDVVQEEEEEVEEEEEEEEEEDDEDDHVSVKRKYNF
What is the function of this protein?
Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.
What are the official names of this protein?
Transcription elongation factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ELOF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA_FRACC
Sequence: MRVLAAMSGGVDSAVAAARAVDAGHDVTGVHLALSRSPESDRTGARGCCTIEDARDARRAADILGIPFYVWDLADRFETDVIEEFVESYAAGRTPNPCVRCNERIKFAAVLDKALALGFEAVVTGHHARLDPDGTLRRSVDPDKDQSYVLGTLRPEQLAAARFPLGDSTKAQVRVEAAERRLAVADKPDSHDICFISHGDTGGWLRERLGPRPGPVIDATTGQTLGHHDGAYAFTVGQRRGLKLGRPAADGRPRYVLDISPVTSTVTVGPAEALDVRRLVADRAVWPHEGAVSCLAQVRAHGGVVPAVAQARDEELVVTLTTPVRGTAAGQAVVLYDGDRVLGGGHIRTTGG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_PERMH
Sequence: MEDFIKGLAERVLEGEKLSKEDGLKILSIPDEYLDLLVQEASKVREAVFGDEVEFCSLINAKNGACSEDCSFCAQSSKYPTPINAYGLVPKKELVEGAQKAVSIKANRYCIVTSGKRATKEEVEQIADAVREITENLPVRVCVSIGTVDEEDLKLLKDSGVDRVNHNLETSERHFKNIVTTHSYKERLETIKTVQKVGLSTCTGGIFGIGETDEDIVDLASVYRELNVNSIPMNFLIPIPGTPLEGNKQLTPQRCLKIISLFKLFNPQAELRLCGGREINLREYHDTAMEIANCVMAGGYLTRAGRAPGKDEEMVRRLGRKLITGRDLFSKYKTAV
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CHER_BACSU
Sequence: MDTYSVFTTKWKQLTGVDLTLYKEAQMKRRLTSLYEKKGFQSFKDFAAALEKDQALLNETLDRMTINVSEFYRNYKRWEVLETAILPLIKTSRPLKIWSAACSTGEEPYTLAMLLDQQKGLPGYQILATDIDEKALEKAKKGVYQERSLQEVPLSVKDRYFTQNANRSYEVKTEIKKNITFKKHNLLADRYEQDFDLIVCRNVFIYFTESAKEELYLKMAHSLKKNGVLFVGSTEQIFNPEKFGLVPADTFFYQKR
What is the function of this protein?
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.  CheR is responsible for the chemotactic adaptation to repellents.
What are the official names of this protein?
Chemotaxis protein methyltransferase.
Protein: ATPB_BACC3
Sequence: MNKGRVTQIMGPVVDVKFDGGKLPEIYNALTVKQSNENGTSINLTFEVALHLGDDTVRTVAMSSTDGLVRGTEVEDTGKAISVPVGDATLGRVFNVLGDAIDLDGEVPADVRRDPIHRQAPAFEELSTKVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYHEMSDSGVIKKTAMVFGQMNEPPGARQRVALTGLTMAEHFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTNKGSITSIQAVYVPADDYTDPAPATTFAHLDATTNLERRLTQMGIYPAVDPLASTSRALSPEIVGEEHYEVARQVQQTLQRYKELQDIIAILGMDELSEEDKLVVHRARRIQFFLSQNFHVAEQFTGQKGSYVPVKETVRGFKEILEGKYDDLPEDAFRLVGGIEEVIENAKKMMA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS11_SALCH
Sequence: MAKAPVRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RBFA_XYLFM
Sequence: MPKKSFQRTERISVQIRRDLGAFVQAAVRDHGLPSMSVSDVEVTRDMAHAKVFVTVLQAERSFEAVAGLKALARELRMQLAQTMRLRFVPELHFHYDDSLDRGERINTLLRDLIPPADAEKDESG
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.