PharMolix/UniProtQA huggingface dataset:
Protein: HSP68_DROME
Sequence: MPAIGIDLGTTYSCVGVFQYGKVEIIANDQGNRTTPSYVAFTDSERLIGDAAKNQVAMNPKNSVFDAKRLIGRRFDDSKIQEDIKHWPFKVINDNGKPKISVEFKGANKCFSPEEISSMVLTKMKETAEAYLGTTVKDAVITVPAYFNDSQRQATKDAGAIAGINVLRIINEPTAAALAYGLDKNLKGERNVLIFDLGGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVNHFAEEFKRKYKKDLRSNPRALRRLRTAAERAKRTLSSSTEASLEIDALYEGHDFYSKVSRARFEELCGDLFRNTLEPVEKALKDAKMDKSQIHDIVLVGGSTRIPKVQNLLQNFFGGKTLNLSINPDEAVAYGAAIQAAILSGDKSSEIKDVLLVDVAPLSLGIETAGGVMTKLIERNSRIPCKQSKTFTTYADNQPAVTIQVFEGERALTKDNNVLGTFDLTGVPPAPRGVPKIDVTFDLDANGILNVTAKEQGTGNAKNITIKNDKGRLSQADIDRMLSEAEKYAEEDERHRQRIAARNQLETYLFGVKEAAENGGDRISAADKSSIVERCSEAMKWLDSNTTAEKEEYEYKLKELEQFCSPIMTKMHKGGGDGQQAPNFGQQAGGYKGPTVEEVD
What are the official names of this protein?
Heat shock protein 68.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CEL3B_MAGO7
Sequence: MRWSSPTSSSLSLVALLLVAHVDAAERATSPPVHPSPPMKGAGVWSAAYASAKELVSQMTLEEMVNITGGFATTENVCAGNTGTVPRLGWPGLCLHDAGNGVRATDLVSAYPSGLHVGASWDKNLTYERGLYMGKEFKAKGVNVLLGPNAGALGRVPVAGRNWEGFTIDPYLSGILNAESIVGHQEAGVIATTKHFIGNEQELYRRPYFGVEAVSSNIDDKTVHELYMWPFMDSVKAGAASAMCSYQRVNNTYACMNSKLMNGLLKGELEFEGFIMLDWNAVHTVDSAEAGLDMVMPRGNWGTNLTAAINNGTTSKERLVDMATRIVAAWYFVGQDGDKFPKPGVGMYNLTQPHTPVEARVSESKPIIMEGAVAGHVLLKNEKNALPLKKPKMLSVYGYDATVPRTKNTDVLFTLGYYSSAEMAQAVLGTEQHFDQAAKGGTIISGGRAGANGPPYISDPLSAIQHRAADDDTWVNWDLDSGNPDVNSGSDACLVFINAIATEGWDRDGLHDDFSDGLVLNVASKCENTIVVIHNAGVRLVDQWVDHPNVTALVMAHLPGQDSGAALVKLLYGEEYFSGKLPYTIPHNESDYGHVYRSCAHDRAQDDKDPQCDFTEGVYIDYRDFDARNVTPRFEFGFGLGYTTFEFSELSIETSENLTAGVGSGSIWDHVAIVHATIKNNGSADGAEVAQLYLGIPNSPPKQLRGFEKVALSPGVSAPVRFELTRRDFSIWDVVAQKWVVQEGSYSVHVGASSRDIRLSDDIKI
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose.  Shows higher activities on cellobiose and cellotriose but lower activities on laminarioligosaccharides and polymers.
What are the official names of this protein?
Beta-glucosidase cel3A, Beta-D-glucoside glucohydrolase cel3A, Cellobiase cel3A, Gentiobiase cel3A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y526_SYNWW
Sequence: MLFELIFIFLARVLDVSLGTVRMILVIRGDRIPAAIIGFFEILIYTVALGLVIGSLNEPLKLLVFCSGFALGILLGSILEEKIALGYRGVQVTIDSEHGHIVEELREEGFPVTCWEASGKAGSKLVLNIFLKRNMAVAVADKIYEKDPDAFVVFMEPKHFQGGYIKKK
What are the official names of this protein?
UPF0316 protein Swol_0526.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEXA_STRCO
Sequence: MSDAANPEGHKRSLPGRPPGIRADSSGLTDRQRRVIEVIRDSVQRRGYPPSMREIGQAVGLSSTSSVAHQLMALERKGFLRRDPHRPRAYEVRGSDQAASVQPTDTAGKPAASYVPLVGRIAAGGPILAEESVEDVFPLPRQLVGDGELFVLKVVGDSMIEAAICDGDWVTVRRQPVAENGDIVAAMLDGEATVKRFKREDGHVWLLPHNSAYEPIPGDDATILGKVVAVLRRV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: MPAF_PENBR
Sequence: MVEILDYTKALEVLKEYPSGDGLHVDTLLDSDNHGALTYNDFLILPGSITFSAADVSLDTKVTRRFTIKAPLLSSPMDTVTEHNMAIHMALLGGLGVIHNNCPPDDQAEMVRKVKRYENGFILDPVVLSPSTTVAEAKELKTKWNFGGFPVTEKGTLHSKLLGIVTSRDIQFHKTPEDPVTAVMSTDLVTAPAGTTLAEANEVLRSSKKGKLPIVDKDGLLVSLLSRSDLMKNIHYPLASKLPSKQLLCAAAISTHDADKVRLQKLVDAGLDIVVVDSSQGNSMYQIAMIKWIKSTFPDIDIIAGNIVTREQAAALIAAGADGLRIGMGSGSACITQEVMAVGRPQAASVRSVSAFAARFGVPTIADGGVQNLGHIVKGLALGASAVMMGSLLAGTTESPGEYYVSNEGQLVKAFRGMGSIAVMEDKGKSGGGKNAGASRYFSENDKVKVAQGVAGSVVDRGSITQYVPYLVAGIQHSLQDIGVQDLEALHTGVNNGQVRFEMRSASAQTEGNVHGLHSHEKKLYSS
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).  Part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world (PubMed:21398490).  Does not play a role in the biosynthesis of MPA, but is involved in self resistance to MPA, since MPA acts as an inhibitor of IMP dehydrogenases (PubMed:21923907).
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH, Mycophenolic acid biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_FLAPJ
Sequence: MSKQVRVRFAPSPTGALHIGGVRTALFNYLFAKKHNGVFYLRIEDTDQNRFVPGAEKYILEALKWLGISPDETIGKNEKFGPYRQSERKHLYKQYADLLINSGWAYYAFDTSESLDTLRKITEAAGNTFIYNHTVRETLDNSLTNSPEKVAERIANGEDYVIRFKTPVNETLHLKDIIRGDIKFETNLLDDKVLFKSDGMPTYHLANIVDDHLMETSHVIRGEEWLPSMPLHVLLYRAFGWEAPEFAHLPLILKPVGNGKLSKRDGEKLGFPVFPLQWKTNEGTSLGYKENGFFPETVINFLAMLGWNDGTQQEIFSLEELVQKFDLNRIHKAGAKFDPEKNKWFNHQYLVKKEDSTLAELFLPILASKGIVTNLDYTTKVVALVKERAHFVNELWDLSDYFFIAPTSYDEKATKNWKEETPELMKQLIVVLNGIEDFTSLNIETIVKDWMTQNEIGMGKVMQPFRLSLVGKMMGPHLFDIIEMIGKKETINRIEKAIATL
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRPL_PSESY
Sequence: MLPNLVILDVTEPRKPSSSAGIRQLTADQIQMLRAFIQKRVKNADDVDDILQCVFLEALRNEHKFQHASKPQTWLCGIALNLIRNHFRKMYRQPYQESWEDDVHTDLEWHGDITHQVDGHRQLARVIEAIDCLPTNMQKVLEVSLEMDGNYQETANTLGVPIGTVRSRLSRARVQLKQQIDPFA
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in the activation of hprD as well as other hrp loci which are involved in plant pathogenicity, hrmA and avr genes.
What are the official names of this protein?
RNA polymerase sigma factor HrpL.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
Protein: DICER_MOUSE
Sequence: MKSPALQPLSMAGLQLMTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELAHQIRGDLNPHAKRTVFLVNSANQVAQQVSAVRTHSDLKVGEYSDLEVNASWTKERWSQEFTKHQVLIMTCYVALTVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCESCPSCPRILGLTASILNGKCDPEELEEKIQKLERILRSDAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYERLLMELEAALDFINDCNVAVHSKERDSTLISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTLLRKIHALCEEYFSPASLDLKYVTPKVMKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDDDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRSKQMEAEFRKQEEVLRKFRAHETNLLIATSVVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYVMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSADGAEADVHAGVDDEDAFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMDSVRLAERVVALICCEKLHKIGELDEHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAIPECLRESYPKPDQPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELKKSGFTLSQQMLELITRLHQYIFSHILRLEKPALEFKPTGAESAYCVLPLNVVNDSGTLDIDFKFMEDIEKSEARIGIPSTKYSKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHLNQKGKALPLSSAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHCLLTAEELRAQTASDAGVGVRSLPVDFRYPNLDFGWKKSIDSKSFISTCNSSLAESDNYCKHSTTVVPEHAAHQGATRPSLENHDQMSVNCKRLPAESPAKLQSEVSTDLTAINGLSYNKNLANGSYDLVNRDFCQGNQLNYFKQEIPVQPTTSYPIQNLYNYENQPKPSNECPLLSNTYLDGNANTSTSDGSPAVSTMPAMMNAVKALKDRMDSEQSPSVGYSSRTLGPNPGLILQALTLSNASDGFNLERLEMLGDSFLKHAITTYLFCTYPDAHEGRLSYMRSKKVSNCNLYRLGKKKGLPSRMVVSIFDPPVNWLPPGYVVNQDKSNSEKWEKDEMTKDCLLANGKLGEACEEEEDLTWRAPKEEAEDEDDFLEYDQEHIQFIDSMLMGSGAFVRKISLSPFSASDSAYEWKMPKKASLGSMPFASGLEDFDYSSWDAMCYLDPSKAVEEDDFVVGFWNPSEENCGVDTGKQSISYDLHTEQCIADKSIADCVEALLGCYLTSCGERAAQLFLCSLGLKVLPVIKRTSREKALDPAQENGSSQQKSLSGSCAAPVGPRSSAGKDLEYGCLKIPPRCMFDHPDAEKTLNHLISGFETFEKKINYRFKNKAYLLQAFTHASYHYNTITDCYQRLEFLGDAILDYLITKHLYEDPRQHSPGVLTDLRSALVNNTIFASLAVKYDYHKYFKAVSPELFHVIDDFVKFQLEKNEMQGMDSELRRSEEDEEKEEDIEVPKAMGDIFESLAGAIYMDSGMSLEVVWQVYYPMMQPLIEKFSANVPRSPVRELLEMEPETAKFSPAERTYDGKVRVTVEVVGKGKFKGVGRSYRIAKSAAARRALRSLKANQPQVPNS
What is the function of this protein?
More active than isoform 1 to process long double-stranded RNA into siRNAs.  Responsible for the accumulation of endogenous siRNAs observed in mouse oocytes compared to somatic cells and it regulates meiotic spindle organization in female germline.
What are the official names of this protein?
Endoribonuclease Dicer, Double-strand-specific ribonuclease mDCR-1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_VARPS
Sequence: MIKLFVGLGNPGPEYEATRHNAGFWWIDALARDWKLNLVPERSYHGLAARTNIGGQSVWLLEPQTFMNLSGKSVGALARFFKIAPEEILVVHDELDVVPGQAKLKFGGSHAGHNGLRDIHAQLGTGDYWRLRLGIGHPGVKSEVINWVLKKPLKEQREAIEDAIVRTLHAAPALVAGEMEKATLIIHTSKPPRPKPPRREPGDGGTPATA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_RHIWR
Sequence: MARRRRPEKREILPDPKFGDVVLSKFMNSVMLDGKKSVAEGIVYGALETIETRAKREPLGVFHEALNNVKPGIEVRSRRVGGATYQVPVEVRPDRSQALAIRWLISAARARSEHTMAGRLSGELLDAANNRGNAVKKREDTHRMAEANRAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: AROD_SHIFL
Sequence: MKTVTVKDLVIGAGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLVGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: ALDH_ASPNG
Sequence: MSDLFATITTPNGVKYEQPLGLFIDGEFVKGAEGKTFETINPSNEKPIVAVHEATEKDVDTAVAAARKAFEGSWRQVTPSTRGRMLTKLADLFERDAEILASIEALDNGKSITMAHGDIAGAAGCLRYYGGWADKIHGQTIDTNSETLNYTRHEPIGVCGQIIPWNFPLLMWAWKIGPAIATGNTVVIKTAEQTPLSGLYAANVIKEAGIPAGVVNVISGFGRVAGSAISHHMDIDKVAFTGSTLVGRTILQAAAKSNLKKVTLELGGKSPNIVFNDADIDNAISWANFGIFYNHGQCCCAGSRILVQEGIYDKFIARLKERALQNKVGDPFAKDTFQGPQVSQLQFDRIMEYIQHGKDAGATVAVGGERHGTEGYFIQPTVFTDVTSDMKINQEEIFGPVVTVQKFKDVEDAIKIGNSTSYGLAAGIHTKDVTTAIRVSNALRAGTVWVNSYNLIQYQVPFGGFKESGIGRELGSYALENYTQIKAVHYRLGDALF
What are the official names of this protein?
Aldehyde dehydrogenase, ALDDH, ALDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: NDHI_RIEOB
Sequence: MFPMVTEFMNYGQQTIRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTIFNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GAG_MLVRD
Sequence: MGQTVTTPLSLTLEHWGDVQRIASNQSVEVKKRRRVTFCPAEWPTFDVGWPQDGTFNLDIILQVKSKVFSPGPHGHPDQVPYIVTWEAIAYEPPSWVKPFVSPKLSLSPTAPILPSGPSTQPPPRSALYPALTPSIKPRPSKPQVLSDNGGPLIDLLTEDPPPYGEQGPSSPDGDGDREEATYTSEIPAPSPMVSRLRGKRDPPAADSTTSRAFPLRLGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLTTHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGNDGRPTQLPNEVNSAFPLERPDWDYTTPEGRNHLVLYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDHGQETSVSMSFIWQSAPDIGRKLERLEDLKSKTLRDLVREAEKIFNKRETPEEREERFRRETEENEERRRAEDEQREKERDRRRQREMSKLLATVVTGQRQDRQGGERKRPQLDKDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLDD
What is the function of this protein?
Involved in the packaging and encapsidation of two copies of the genome.  Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome.  This binding is dependent on genome dimerization.
What are the official names of this protein?
Gag polyprotein, Core polyprotein.
What are the subcellular locations of this protein?
[Gag polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. SUBCELLULAR LOCATION: [Matrix protein p15]: Virion. SUBCELLULAR LOCATION: [Capsid protein p30]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p10-Gag]: Virion. SUBCELLULAR LOCATION: [RNA-binding phosphoprotein p12]: Host cytoplasm. Note=Localizes to the host cytoplasm early in infection and binds to the mitotic chromosomes later on.
Protein: TENA_MOUSE
Sequence: MGAVTWLLPGIFLALFALTPEGGVLKKIIRHKRESGLNMTLPEENQPVVFNHIYNIKLPMGSQCSVDLESASGEKDLTPTPESSGSFQEHTVDGENQIVFTHRINIPRRACGCAAAPDVKELLSRLEELELLVSSLREQCTMGTGCCLQPAEGRLDTRPFCSGRGNFSAEGCGCVCEPGWKGPNCSEPDCPGNCNLRGQCLDGQCICDEGFTGEDCSQLACPNDCNDQGRCVNGVCVCFEGYAGPDCGLEVCPVPCSEEHGMCVDGRCVCKDGFAGEDCNEPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGELTCPNDCQGRGQCEEGQCVCNEGFAGADCSEKRCPADCHHRGRCLNGQCECDDGFTGADCGDLQCPNGCSGHGRCVNGQCVCDEGYTGEDCSQRRCPNDCHNRGLCVQGKCICEQGFKGFDCSEMSCPNDCHQHGRCVNGMCICDDDYTGEDCRDRRCPRDCSQRGRCVDGQCICEDGFTGPDCAELSCPSDCHGHGRCVNGQCICHEGFTGKDCKEQRCPSDCHGQGRCEDGQCICHEGFTGLDCGQRSCPNDCSNQGQCVSGRCICNEGYTGIDCSEVSPPKDLIVTEVTEETVNLAWDNEMRVTEYLIMYTPTHADGLEMQFRVPGDQTSTTIRELEPGVEYFIRVFAILENKRSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKKVTTTRLDAPSHIEVKDVTDTTALITWFKPLAEIDSIELSYGIKDVPGDRTTIDLTHEDNQYSIGNLRPDTEYEVSLISRRVDMASNPAKETFITGLDAPRNLRRVSQTDNSITLEWRNVKADIDSYRIKYAPISGGDHAEIDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKGDKESDPATINAATEIDAPKDLRVSETTQDSLTFFWTTPLAKFDRYRLNYSLPTGQSMEVQLPKDATSHVLTDLEPGQEYTVLLIAEKGRHKSKPARVKASTEEVPSLENLTVTEAGWDGLRLNWTADDLAYEYFVIQVQEANNVETAHNFTVPGNLRAADIPGLKVATSYRVSIYGVARGYRTPVLSAETSTGTTPNLGEVTVAEVGWDALTLNWTAPEGAYKNFFIQVLEADTTQTVQNLTVPGGLRSVDLPGLKAATRYYITLRGVTQDFGTAPLSVEVLTEDLPQLGGLSVTEVSWDGLTLNWTTDDLAYKHFVVQVQEANNVEAAQNLTVPGSLRAVDIPGLKADTPYRVSIYGVIQGYRTPMLSTDVSTAREPEIGNLNVSDVTPKSFNLSWTATDGIFDMFTIEIIDSNRLLQTAEHNISGAERTAHISGLPPSTDFIVYLSGIAPSIRTKTISTTATTEALPLLENLTISDTNPYGFTVSWTASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVLVSGFTQGHQTKPLRAETITEAEPEVDNLLVSDATPDGFRLSWTADEGIFDSFVIRIRDTKKQSEPQEISLPSPERTRDITGLREATEYEIELYGISRGRRSQPVSAIATTAMGSPKEIMFSDITENAATVSWRAPTAQVESFRITYVPMTGGAPSMVTVDGTDTETRLVKLTPGVEYRVSVIAMKGFEESDPVSGTLITALDGPSGLLIANITDSEALAMWQPAIATVDSYVISYTGERVPEVTRTVSGNTVEYELHDLEPATEYILSIFAEKGQQKSSTIATKFTTDLDSPREFTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYSARIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQDHGESAYAVYDRFSVGDAKSRYKLKVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSNFRNLEGRRKRA
What is the function of this protein?
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration.  Promotes neurite outgrowth when provided to neurons in culture.  May play a role in supporting the growth of epithelial tumors.  Ligand for integrins ITGA8:ITGB1, ITGA9:ITGB1, ITGAV:ITGB3 and ITGAV:ITGB6.  In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (By similarity).
What are the official names of this protein?
Tenascin, TN, Hexabrachion, Tenascin-C, TN-C.
What is the protein family that this protein belongs to?
Belongs to the tenascin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ALG14_CANAL
Sequence: MDIETAACFSIAFIATPILIVLVRLLFILPSLRLPTSVKKKKKLIQECQLSILLGSGGHTGEMMRIISKLDMGKVSRTWIYTSGDNASLAKAQDYERKSGTSSQYIPIPRARTVGQSYISSIPTTIYSFLFSAIAMLKHRPAVILLNGPGTCVPVAYILFLYKLLGLCNTKIIYIESLARVNKLSLSGLLLLPISDRFIVQWESLYQQYSRVEYYGILI
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway.  Anchors the catalytic subunit ALG13 to the ER (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG14, Asparagine-linked glycosylation protein 14.
What is the protein family that this protein belongs to?
Belongs to the ALG14 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: BGLK_KLEPN
Sequence: MKIAAFDIGGTALKMGVMARDGRLLETARQSINDSDGDRILQAMLSWLAAHPSCEGIAISAPGYIDPHSGLITMGGAIRRFDNFAMKSWLETRTGLPVSVENDANCVLLAERWQGKAAEMANFLVLTIGTGIGGAIFCQHQLINGARFRAGEFGYMLTDRPGGRDPRRYSMNENCTLRVLRHRYAQHIGAPLDSVTGELIFDRYDAGDPVCQRLVAEFFNGLGHGLYNLVHIFDPQTIFIGGGVVERPGFLTLLRQHLAWFGIADYLDTVSHGNDAGLIGAVYHFNQLYRSPDDDRH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of a wide variety of beta-D-glucosides, to produce 6-phospho-beta-D-glucosides including cellobiose-6'-P, gentiobiose-6'-P, cellobiitol-6-P, salicin-6-P, and arbutin-6-P.  Is not able to phosphorylate alpha-D-glucosides.  May have a dual role of kinase and transcriptional regulator of the cellobiose-PTS operon.
What are the official names of this protein?
Beta-glucoside kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: TOP1_VAR67
Sequence: MRALFYKDGKLFTDNNFLNPVSDNNPAYEVLQHVKIPTHLTDVVVYGQTWEEALTRLIFVGSDSKGRRQYFYGKMHVQNRNAKRDRIFVRVYNVMKRINCFINKNIKKSSTDSNYQLAVFMLMETMFFIRFGKMKYLKENETVGLLTLKNKHIEISPDKIVIKFVGKDKVSHEFVVHKSNRLYKPLLKLTDDSSPEEFLFNKLSERKVYECIKQFGIRIKDLRTYGVNYTFLYNFWTNVKSISPLPSPKKLIALTIKQTAEVVGHTPSISKRAYMATTILEMVKDKNFLDVVSKTTFDEFLSIVVDHVKSSTDG
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
Protein: TIMP2_CAVPO
Sequence: MGATARSLRLALGLLLLGTLPRGADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKSINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
What is the function of this protein?
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor.
What are the official names of this protein?
Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2, TIMP-2.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I35 (TIMP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14_STRA5
Sequence: MAKKSKIAKFQKQQKLVEQYAELRRELKEKGDYEALRKLPKDSNPNRLKNRDLIDGRPHAYMRKFGMSRINFRNLAYKGQIPGIKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: ANM61_ORYSJ
Sequence: MLPSHLNGHSPLARRCPRLSAASPPATGDSDAAAAAADAPLAEHDRIYFQSYSHIGIHEAMIKDRVRTDAYRSAIMHHQKFIEGKVVMDVGCGTGILSVFCARAGAKCVYAVEASEMATQAREIVKANNLDDKVVVVHGRVEDVEVEDKVDVIISEWMGYMLLYESMLPSVLFARDKWLKPGGLILPSHATLFMAPITNSERYEGSVDFWSDVYGINMSALVPLAKKFTSEEPSIEIIGGENVLSWPFVVKHIDCYTFKAEELKSFTTKYKVSSMMLAPIHGFGLWFEVEFNGPSNPTDKSPSDLNPLDVIRKKRRRGSEDPVVLSTAPEDEPTHWHQTILYFPDPIEVKQDQIIEGSVKVSQSEENPRFLNIQLDCTTGGQTLVKDYAMR
What is the function of this protein?
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA).
What are the official names of this protein?
Probable protein arginine N-methyltransferase 6.1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT6 subfamily.
Protein: ATPE_SACEN
Sequence: MANMSVQLVAVERRLWSGEATAVVAQTTEGEIGILSGHEPVLGQLVEGGVVKITTPEKETVTAAVHGGFLSVTADGVSVLAESAELADEIDVAQAREDVKRGDEQARARALSRLRAAGHSS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: COAA_STRA1
Sequence: MNNEFINFDRISRENWKDLHQQSQALLTEKELESIKSLNDNINIQDVIDIYLPLINLIQIYKRSQENLSFSKAIFLKKENYQRPFIIGISGSVAVGKSTTSRLLQLLISRTFKDSHVELVTTDGFLYPNEKLIQNGILNRKGFPESYDMESLLNFLDTIKNGITAKIPIYSHEIYDIVPNQLQTIETPDFLILEGINVFQNQQNHRLYMNDYFDFSIYIDAENKQIEEWYLQRFNSLLQLAEADPSNYYHKFTQIPPHKAMELAKDIWKTINLVNLEKYIEPTRNRADFIIHKGKHHKIDEIYLKK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.