PharMolix/UniProtQA huggingface dataset:
Protein: SYN_STRR6
Sequence: MTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTAFFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITDIEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYVTYEFFDKNGFMKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTELLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPTFVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDELGMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_YERPN
Sequence: MTQNLSQLEHNDAFIQRHIGSSVEQQQQMLAAVGASSLSTLIQQIVPADIQLPGPPPVGEAATEHQALAELKGIASQNQCYKSYIGMGYSPVLTPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQLTQDLTGLDLASASLLDEATAAAESMALAKRASKLKDANRFFVADDVHPQTLDVVLTRAETFGFDVIVDRAEKVLELDGIFGVLLQQVGTTGELHDYSALLAELKKRKIITSVAADIMALVLLTAPGAQGADVVFGSAQRFGVPMGYGGPHAAFFACRDEFKRSMPGRIIGVSRDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPQGLQRIAGRIHRMTDILAAGLQHAGLTLRFKHWFDTLTVEVKDKAAVLARALSFGINLRTDIHGAVGITLNETTSREDIQTLFALFVGDNHGLDIDQLDAAVSQHSQSIQDSMLRRDPILTHPVFNRYHSETEMMRYMHRLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAAGYQQMIGQLSQWLVQLTGYDAVCMQPNSGAQGEYAGLLAIRRYHESRNQANRHICLIPSSAHGTNPASAQMAGMSVVVVACDKQGNIDLHDLRQKAEHAGDELSCIMVTYPSTHGVYEETIREVCQIVHQFGGQVYLDGANMNAQVGITTPGYIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIDGMTTQQGAVSAAPFGSASILPISWMYIRMMGADGLKQASQVAILNANYIATRLKNAYPVLYTGHDGRVAHECILDIRPLKEATGISEMDIAKRLIDFGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIEKVAQGEWPLEDNPLVNAPHTQAELVGEWTHPYSRELAVFPVAGVLENKYWPTVKRLDDVYGDRNLFCSCVPISDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: ALAM_YEAST
Sequence: MLSLSAKNHFTVSNSITHVIKSYHIRTLTSSAEKMPHITTPFSTSASSTKLKAFRKVRPVLQRHSSSWIVAQNHRRSLSGQSSLNDLRHLNRFPHHTLKTSNNEFYPAEQLTLEDVNENVLKAKYAVRGAIPMRAEELKAQLEKDPQSLPFDRIINANIGNPQQLQQKPLTYYRQVLSLLQYPELLNQNEQQLVDSKLFKLDAIKRAKSLMEDIGGSVGAYSSSQGVEGIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRGPETGVLIPIPQYPLYTATLALNNSQALPYYLDENSGWSTNPEEIETVVKEAIQNEIKPTVLVVINPGNPTGAVLSPESIAQIFEVAAKYGTVVIADEVYQENIFPGTKFHSMKKILRHLQREHPGKFDNVQLASLHSTSKGVSGECGQRGGYMELTGFSHEMRQVILKLASISLCPVVTGQALVDLMVRPPVEGEESFESDQAERNSIHEKLITRAMTLYETFNSLEGIECQKPQGAMYLFPKIDLPFKAVQEARHLELTPDEFYCKKLLESTGICTVPGSGFGQEPGTYHLRTTFLAPGLEWIKKWESFHKEFFDQYRD
What are the official names of this protein?
Probable alanine aminotransferase, mitochondrial, Glutamate pyruvate transaminase, GPT, Glutamic--alanine transaminase, Glutamic--pyruvic transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: COBS_THEM4
Sequence: MIYDFLLSLGFISRIPINIKVKAFEVRVKRLPIYFPLVGYIPGILFFFGGSFENFLLKILFLILGYYFFDLFHFDGFLDTLDGFLNQSSKEKRLEIMSKGDVGPFAVFFGTLYVVVFWTLYLEIPPITFIYSSVFGRYSMNLLMFFSKPAKKTGLGALFFPFQKKNLLFSSFFLLPLLFSMKYFFISYVVTVVFSYLMSIVSNSKIGGVTGDVLGGACLMTNGLLLVVLGVV
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATG5_CAEEL
Sequence: MDYEVCRKVWESHVPCQFTLQSSGGTHGEPLPFYTMLPRFSYLALAIQKVLSSFNRRDDGEKVHSDKMWLEHNGIPLKMYIPIGVIYDQANLSENDSILEIIVRTSQPPPQFQMVDRDMMEAMFMQNIKEADYLKTKAEITKNMMKDESAQLWRSVCNIPDNFDEFWTIVQKLMETSEGNEFAHIPLRVYVKNQAFKQALITAKHPDGSLRTIGEAVSDVLSSSSSSSTDSQSEHPPRLISHGIDIPHHTPLIFAAKNLSYPDNFIHVVLLLVVP
What is the function of this protein?
Involved in autophagic vesicle formation (By similarity).  Conjugation with lgg-3/ATG12, through a ubiquitin-like conjugating system involving atg-7 as an E1-like activating enzyme and atg-10 as an E2-like conjugating enzyme, is essential for its function (By similarity).  Most likely a component of an atg-5-lgg-3-atg-16 complex that promotes autophagosome formation by associating with lgg-2, but not lgg-1, at the preautophagosomal membrane (PubMed:24185444).  Probably, as part of an atg-5-lgg-3-atg-16 complex, required for lgg-1 lipidation; the complex acts as an E3-like enzyme promoting atg-3-mediated lgg-1 lipidation (Probable).  Furthermore, association with atg-16. 2 is required for the nucleation of lgg-1 positive autophagic vesicles (PubMed:24185444).
What are the official names of this protein?
Autophagy-related protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: TCAA_STAAD
Sequence: MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNNIKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTKDNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRVSKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFIPGTYRIPAMKSTENGDFAGYLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSKKVTINDREMAFSSSKTYGPYPQNKDITISASGKAKGKTFTTQTKTIKASDLKYNTEITLNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSSFYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQDRLQLIKTSEK
What is the function of this protein?
Plays a major role in decreasing resistance to glycopeptide antibiotics.
What are the official names of this protein?
Membrane-associated protein TcaA.
What is the protein family that this protein belongs to?
Belongs to the TcaA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RLMM_ECO5E
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPT_HELHP
Sequence: MKPSYPQHIAVIMDGNGRWAKKQGKKRTQGHKEGAKIVRDITQWCAEKGIPYLTLYAFSTENWKRPKIEVDFLMKLLEKYLHDEKPVYMKNHIRFRVIGDISVFNTRLKNAILELEHATQNHTKLTQILALNYGSRDEIARTFIKLAHTLTPHTLASLSSQDIISMINANLDTATLPDVDMLIRTGGEKRISNFMLWQASYAELFFTPTLFPSFGKNELNAMLEEFLQRQRRFGGVE
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: FYPP1_ARATH
Sequence: MDLDQWISKVKDGQHLSEDELQLLCEYVKEILIEESNVQPVNSPVTVCGDIHGQFHDLMKLFQTGGHVPETNYIFMGDFVDRGYNSLEVFTILLLLKARHPANITLLRGNHESRQLTQVYGFYDECQRKYGNANAWRYCTDVFDYLTLSAIIDGTVLCVHGGLSPDVRTIDQIRLIERNCEIPHEGPFCDLMWSDPEDIETWAVSPRGAGWLFGSRVTTEFNHINNLDLVCRAHQLVQEGLKYMFQDKGLVTVWSAPNYCYRCGNVASILSFNDNMEREVKFFTETEENNQMRGPRTGVPYFL
What is the function of this protein?
Catalytic subunit of protein phosphatase 6 (PP6) (Probable).  Dephosphorylates phosphorylated phytochromes, with a preference toward Pfr forms.  Plays a major role in the photoperiodic control of flowering time in long days by modulating phytochrome signals in flowering time control (By similarity).  Involved in the regulation of polar auxin transport in roots (PubMed:22715043).  Dephosphorylates directly the auxin efflux carriers PIN1 and PIN2, thus promoting their proper polar localization in root cell plasma membrane (PubMed:22715043).  Acts antagonistically with the protein kinase PID to regulate the reversible phosphorylation of PIN and polar targeting, subsequently impacting polar auxin transport and plant development (PubMed:22715043).  Involved in the regulation of abscisic acid (ABA) signaling during seed germination and postgermination seedling growth (PubMed:23404889).  Functions as negative regulator of ABA signaling through direct dephosphorylation and destabilization of ABI5 (PubMed:23404889).  Acts antagonistically with the protein kinase SRK2E/SNRK2. 6 to regulate ABI5 phosphorylation and ABA responses (PubMed:23404889).  Involved in the regulation of phosphorylation status in hypocotyl phototropism (PubMed:30373470).  Involved in the negative regulation of photomorphogenesis by controlling the stability and transcriptional activity of PIF3 and PIF4 proteins in the dark, via the regulation of their phosphorylation status (PubMed:31527236).
What are the official names of this protein?
Phytochrome-associated serine/threonine-protein phosphatase 1, AtFyPP1.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-6 (PP-V) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSGA_YERPS
Sequence: MNNSNRIRLTWISYLSYALTGALVIVTGIVMGNIAEYFNLPIASMSNTFTFLNAGILISIFLNAWLMEIIPLKRQLVFGFILMLIAIAGLMVGHNLMIFSISMFIFGVVSGITMSIGTFLVTHMYEGRQRGSRLLFTDSFFSMAGMIFPIAAAMLLARHIEWYWVYACIGLLYVGIFVLTLCSEFPVLGHKATDQSKPVVKEKWGVGVLFLAIAALCYILGQLGFIQWVPEYATKTFNMNISQAGQLVSNFWISYMIGMWIFSFILRFFDLQRIVTVLAAMATLAMYLFVSTDNPAYLSYYILALGFVSSAIYTTLITLGSLQTKVSSPKLVNFILTCGTVGTMLTFVVTGPIVANNGVHAALATANGLYLAVFILCLALGFFTKHRSHGHVTH
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FEN1_EMENI
Sequence: MGIKHLYQVIAENAPDAIKAGDIKNHFGRKVAIDASMSIYSFLIAVRSEGQQLMSDTGETTSHLMGMFYRTLRMVDNGIKPLYVFDGAPPKLKSGELAKRSARKHEATEAHEEAKETGTAEDVEKFSRRTVRVTREHNAECKKLLKLMGIPYIDAPTEAEAQCAVLARAGKVYAAASEDMDTLCFEAPILLRHLTFSEQRKEPIQEIHLNRALEGLGMDRNQFIDLCILLGCDYLEPIPKVGPNTALKLIRDHGTLEKVVESIEKDPKQKYVIPESWPYQDARELFLNPDVRDANDPECDFKWEAPDIEGLVDFLVKDKGFNEDRVRNGAARLQKNLKTAQQSRLEGFFKPVAKTDAEKATLKRKHDEKIQEQKKRKKEEAKAKKEAKARPRAAV
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: TAP_MYCBO
Sequence: MRNSNRGPAFLILFATLMAAAGDGVSIVAFPWLVLQREGSAGQASIVASATMLPLLFATLVAGTAVDYFGRRRVSMVADALSGAAVAGVPLVAWGYGGDAVNVLVLAVLAALAAAFGPAGMTARDSMLPEAAARAGWSLDRINGAYEAILNLAFIVGPAIGGLMIATVGGITTMWITATAFGLSILAIAALQLEGAGKPHHTSRPQGLVSGIAEGLRFVWNLRVLRTLGMIDLTVTALYLPMESVLFPKYFTDHQQPVQLGWALMAIAGGGLVGALGYAVLAIRVPRRVTMSTAVLTLGLASMVIAFLPPLPVIMVLCAVVGLVYGPIQPIYNYVIQTRAAQHLRGRVVGVMTSLAYAAGPLGLLLAGPLTDAAGLHATFLALALPIVCTGLVAIRLPALRELDLAPQADIDRPVGSAQ
What is the function of this protein?
Efflux pump that contributes to intrinsic antibiotic resistance.  The pump uses the electrochemical gradient as a source of energy.
What are the official names of this protein?
Multidrug efflux pump Tap.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Drug:H(+) antiporter-3 (DHA3) (TC 2.A.1.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LNT_HAEIN
Sequence: MKNLNRILLSIKFMNKYFTYLIAIISGLLGVFAFSPFDYWPLAYVSLLGLLYVAKNPKKSTALLSTFLWAMGFFCFGVSWLNVSIHQFGGASLGVSYFLVGLLAAYLALYPMLFTYLVHHFKVQSAVIFAVIWTLTEFLRGWIFTGFPWLQFGYTQIDSPFYGIAPIFGVTGLTFFTVWASAVIFNLVSSLFKTKNLKLVLANALLLIIVGGLSAYSSRIHFVKSVEDKAISVTLAQGNIEQNLKWDPNYFYSTLAIYQKLITENLGKTDLIILPESALPTLENAITPFFEGLERAAKETKTEIMVGTVFQDTKSGKLLNSIMTAGNPDFPYQPNTQNRYNKHHLVPFGEYVPLESILRPLNSVFNLPMSAFQSGEAVQPSLIAKKRAFSPAICYEIIFGEQVRQNLKQDTDYLLTLSNDAWFGDSIGPWQHLQMARMRALELGKPLIRATNTGISVFVDAQGKVLAQAPQFIETTLTYKIAPAEGKTPYSVLGNMPLYALSLLFLLLHSMMAFIRRKMNIL
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YB8J_YEAST
Sequence: MAATPAAIEVSLTIVFVLFFSADVSLTRNSEMKAHTSKMDSYSSSIYMNVLPTSLAQTSYHLAPISHLKCLSVQFSSHIHYSYYYGASVLERCVFHRSRIRGARFIVPIPFIAFPRHKNVFSQCTYFRRIPLGCLQRCSCSFWPRKSQNQICFEPSLRGHLIFVL
What are the official names of this protein?
Putative uncharacterized protein YBR300C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SWI5_MOUSE
Sequence: MIDENNDVSEEALSSDIKKLKEKHDMLDKEISQLIAEGYRVIELEKHISLLHEYNDIKDVSQMLLGKLAVTRGVTTKELYPDFDLNLND
What is the function of this protein?
Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination.
What are the official names of this protein?
DNA repair protein SWI5 homolog, Protein SAE3 homolog.
What is the protein family that this protein belongs to?
Belongs to the SWI5/SAE3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL21_ALTMD
Sequence: MYAVFQSGGKQHRVAEGQTVRLEKIEVAPGETVEFDKVLMVSNGDDVKIGTPIVAGGKVTAEVVTHGRGDKVKIVKFRRRKHSRKQAGHRQWFTEVKITGINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RECO_BIFA0
Sequence: MALYRDEAVVLRTAKLGEADRIITLLTRDHGKVRAVAKGVRRTKSRFGARLEPFMRVDLLLGEGRTFDSVRQAESISAYAGGITGDYATYTAASAMCETAADLLPAEHEPAAAQYRLLIAALGALSRHLHDPQAIALSYILRAMSLAGWTIRLDSCVVCGSQDVEFFSASAGGAMCPNDHTPDAVRVPVHVFDQLRALEQGDWPQLDMLQTPDPRCENIVREWAQYYLERPIRSLRLLD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: MNMG_SALDC
Sequence: MFYQDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRVLYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVSRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENAKIVRPGYAIEYDFFDPRDLKPTLESKFIHGLFFAGQINGTTGYEEAAAQGLLAGLNAARLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTEMGRELGLVDDERWARFNEKLESIERERQRLKSTWVTPSAESADEVNAHLTTPLSREASGEDLLRRPEMTYAQLTSLAAFAPALEDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNENTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGMLRRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EF2_SCHPO
Sequence: MVAFTPEEVRNLMGKPSNVRNMSVIAHVDHGKSTLTDSLVQKAGIISAAKAGDARFMDTRADEQERGVTIKSTAISLFAEMTDDDMKDMKEPADGTDFLVNLIDSPGHVDFSSEVTAALRVTDGALVVVDTIEGVCVQTETVLRQALGERIRPVVVVNKVDRALLELQISQEELYQNFARVVESVNVVISTYYDKVLGDCQVFPDKGTVAFASGLHGWAFTVRQFANRYAKKFGIDRNKMMQRLWGENYFNPKTKKWSKSATDANGNSNQRAFNMFILDPIYRIFDAVMNSRKDEVFTLLSKLEVTIKPDEKELEGKALLKVVMRKFLPAADALMEMIVLHLPSPKTAQQYRAETLYEGPMDDECAVGIRNCDANAPLMIYVSKMVPTSDRGRFYAFGRVFSGTVRSGLKVRIQGPNYVPGKKDDLFIKAIQRTVLMMGSRIEPIEDCPAGNIIGLVGVDQFLVKSGTLTTSEVAHNMKVMKFSVSPVVQVAVEVKNGNDLPKLVEGLKRLSKSDPCVLCTTSESGEHIVAGAGELHLEICLKDLQEDHAGIPLKISPPVVSYRESVSEPSSMTALSKSPNKHNRIFMTAEPMSEELSVAIETGHVNPRDDFKVRARIMADEFGWDVTDARKIWCFGPDTTGANVVVDQTKAVAYLNEIKDSVVAAFAWASKEGPMFEENLRSCRFNILDVVLHADAIHRGGGQIIPTARRVVYASTLLASPIIQEPVFLVEIQVSENAMGGIYSVLNKKRGHVFSEEQRVGTPLYNIKAYLPVNESFGFTGELRQATAGQAFPQLVFDHWSPMSGDPLDPTSKPGQIVCEARKRKGLKENVPDYTEYYDRL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity).
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_SULDN
Sequence: MIVGVRGVLVSKEPSFVHVDVGGVVYEVFISLQSFSALSGNEVKLFTSHVIREDAQLLYGFLELGEKKLFERLIKINGVGPKVAMAICSTYTPSQFAVVLNNKDITAVQRVPGIGPKSAGRILVELSGFDTELIISASEPKSLAVAQASEALESLGFKKDKISKALGSCSAVDTAILVKEALKLLQTI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: EFTS_BACP2
Sequence: MAITAQLVKELRQKTGAGMMDCKKALTETDGDIDKAIDLLREKGIAKAAKKADRIAAEGLTLIKTDGNTGVILEVNSETDFVAKNEGFQSLLNELADHLLAAKPATIEEAHASKMENGSTVEEHITSAIAKIGEKITLRRFSVITKEDNAAFGSYLHMGGRIGVLAVLNGTTDEELARDIAMHVAAVNPKYISRDQVSEEEANREREVLTQQALQEGKPENIVAKMVEGRLNKFFEEICLLDQAFVKNPDEKVKQVVAAKNASIQTYVRYEVGEGIEKRQDNFAEEVMSQVKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEGT_KOMPG
Sequence: MIMQLGLTSLAFLALKCDAYNIAPKIDTPNVEPFAPSGGLKLLAIVAIIWYVVVLLVAYYGFFEIMQKFSKRKTLPVPPQVEGVTILRPIKGIDPEMELCLQSAFDQDYPKFEIIICVESENDPGIGVAEALIRKYPHVDARILKGDSHNPDHFGPNPKVNNLAKGYSAGKYDIMWILDSNVWVCSGALSRSVDALNRSLDNGRSTFDFQTGKGRKVNLVHHVPMAISINPQTGTNLDEMFLFTSHSKFYISINKAALAPCVNGKSNLYRRSELDLAVKRLGKGSEPSLDGTTGILAKDAAYYGSKPGQGLRFFARYIGEDNMIATALWFQNGGRTGLTGDAAIQPLGGVNSTSLKNYLLRRIRWLRVRKHMVLEATLLEPTTECLLCGTFGTFAISTLFLQSYFNWKFFIFHLLVWMVTDYTQFHILLTNASQDTATCNVPYFAEPNFNAYGSPFESSNLRTFHRWVLYWLLREVLALPIWISAMLGTRIIWRNRPFRINVDLSAEEL
What is the function of this protein?
Catalyzes the final step in the biosynthesis of the membrane lipid glucosylceramide (GluCer), the transfer of glucose to ceramide.  Glucosylceramides play important roles in growth, differentiation and pathogenicity.
What are the official names of this protein?
Ceramide glucosyltransferase, GLCT-1, Glucosylceramide synthase, GCS, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: MUTY_HAEIN
Sequence: MLAKSSINAPFAKSVLAWYDKFGRKHLPWQQNKTLYGVWLSEVMLQQTQVATVIPYFERFIKTFPNITALANASQDEVLHLWTGLGYYARARNLHKAAQKVRDEFNGNFPTNFEQVWALSGVGRSTAGAILSSVLNQPYPILDGNVKRVLARYFAVEGWSGEKKVENRLWALTEQVTPTTRVADFNQAMMDIGAMVCMRTKPKCDLCPLNIDCLAYKNTNWEKFPAKKPKKAMPEKTTYFLILSKNGKVCLEQRENSGLWGGLFCFPQFEDKSSLLHFLAQEKVTHYQEWPSFRHTFSHFHLDIHPIYAEMESTLCVEQANLDWRKVMESTKEYQSNLSSAVKYWYDPQNPEPIGLAQPVKNLLIQFVRNHYGKNSIL
What is the function of this protein?
Adenine glycosylase active on G-A mispairs.  MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
What are the official names of this protein?
Adenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: LPTE_SODGM
Sequence: MRYWTLALVLGLAVTITAGCGYHLRGTTDQVPTEMKTMTLNSYDPYGPLTRAVRAELRLNDVTLVDDAQDKNNTLPSLRIVNSSENQVTASVFQDGKTAEYQMTLGVHAQVLMPGEDYYPIDVKVYRSFFDNPLTALAKDAEGDIIRQEMRQQAAQQLVRKLLTVHAAEEADKALDAKLKQQQPPQPVAPAS
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.