PharMolix/UniProtQA huggingface dataset:
Protein: BGA12_ORYSJ
Sequence: MAARVAAAVAAALLAAALLLPGAAAEWTLTKKGTVVSYDERSLMIDGKRDLFFSGAIHYPRSPPEMWDKLVKTAKMGGLNTIETYVFWNGHEPEPGKYYFEGRFDLIRFLNVIKDNDMYAIVRIGPFIQAEWNHGGLPYWLREIGHIIFRANNEPFKREMEKFVRFIVQKLKDAEMFAPQGGPIILSQIENEYGNIKKDRKVEGDKYLEWAAEMAISTGIGVPWVMCKQSIAPGEVIPTCNGRHCGDTWTLLDKNKPRLWTENWTAQFRTFGDQLAQRSAEDIAYAVLRFFAKGGTLVNYYMYHGGTNFGRTGASYVLTGYYDEAPMDEYGMCKEPKFGHLRDLHNVIKSYHKAFLWGKQSFEILGHGYEAHNYELPEDKLCLSFLSNNNTGEDGTVVFRGEKFYVPSRSVSILADCKTVVYNTKRVFVQHSERSFHTTDETSKNNVWEMYSEAIPKFRKTKVRTKQPLEQYNQTKDTSDYLWYTTSFRLESDDLPFRRDIRPVIQIKSTAHAMIGFANDAFVGTGRGSKREKSFVFEKPMDLRVGINHIAMLSSSMGMKDSGGELVEVKGGIQDCVVQGLNTGTLDLQGNGWGHKARLEGEDKEIYTEKGMAQFQWKPAENDLPITWYKRYFDEPDGDDPIVVDMSSMSKGMIYVNGEGIGRYWTSFITLAGHPSQSVYHIPRAFLKPKGNLLIIFEEELGKPGGILIQTVRRDDICVFISEHNPAQIKTWESDGGQIKLIAEDTSTRGTLNCPPKRTIQEVVFASFGNPEGACGNFTAGTCHTPDAKAIVEKECLGKESCVLPVVNTVYGADINCPATTATLAVQLLLASHVMRIAICVRPMLFARNGIVTSVLAHILGHPEWDRKSLRVKMAGRQNPCPDFTPTKSYGYLFSKPLVALTVSLDSNLSP
What are the official names of this protein?
Beta-galactosidase 12, Lactase 12.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 35 family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: SBMA_ECO57
Sequence: MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQIPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLVEVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVSHYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIAFLPVLVTLSAHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFGLFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHELDGDKIQEVTHTLS
What is the function of this protein?
Uptake of antimicrobial peptides.
What are the official names of this protein?
Peptide antibiotic transporter SbmA.
What is the protein family that this protein belongs to?
Belongs to the peptide uptake permease (PUP) (TC 9.A.18) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WAXS3_ARATH
Sequence: MEEELKNFIKLWISAIISISYCYYLSTGIKAGVFRLLSVLPVCALFLVFPLFFSYVHFSGCMAFFLSWLANFKLILFSFDQGPLSPLPRTLSRFICITCFPIKPQQNPNIQNYKIPIWLFAIKVVIFVVLLQMYEYKQYLSPALLLVFNSLHIFLELEIVFMLVKALVFITLGCDLEPQSNEPYLATSLQDFWGRRWNLMVPAILRPAVYLPARRMACRKVNSDQAMFLGVFAAFLVSGAVHEMLFFYLTREVPTGEVTWFFLLHGVCTVAEVAVKKSTFVRRWWRVSPTVSRLLTVGFVVVTSGWFFFPLIRSGIIERLASEALMCIDFVKHKFLLLLLGD
What is the function of this protein?
Catalyzes the final step in the synthesis of long-chain linear esters (waxes).
What are the official names of this protein?
Probable long-chain-alcohol O-fatty-acyltransferase 3, Wax synthase 3.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: STK35_HUMAN
Sequence: MGHQESPLARAPAGGAAYVKRLCKGLSWREHVESHGSLGAQASPASAAAAEGSATRRARAATSRAARSRRQPGPGADHPQAGAPGGKRAARKWRCAGQVTIQGPAPPRPRAGRRDEAGGARAAPLLLPPPPAAMETGKDGARRGTQSPERKRRSPVPRAPSTKLRPAAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGRSGARVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQLYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQLTSAIAFLHKNHIVHRDLKPDNILITERSGTPILKVADFGLSKVCAGLAPRGKEGNQDNKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKELLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAFELETRMDQVTCAA
What are the official names of this protein?
Serine/threonine-protein kinase 35, CLP-36-interacting kinase 1, CLIK-1, PDLIM1-interacting kinase 1, Serine/threonine-protein kinase 35 L1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Cytoplasm. Note=When associated with PDLIM1, it is mostly found in cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in the nucleus, and the presence of PDLIM1 had no influence on its location.
Protein: MURD_CERSK
Sequence: MIPVRGLEGRKVAVLGLGRSGLATARALEAGGAEPLLWDDSPEARAKAEGQGFTVTDLTRDRAFEGVALLVTSPGIPHLYPAPNPVIARAMAAGVPVDNDIGLFFRSFATRDWDAFDQMPRVVCVTGSNGKSTTTALIHHILSEAGRPTQMAGNIGRGVLDLDPARDGEVVVLELSSYQTDLARALTPDVAVFTNLSPDHLDRHGGMGGYFAAKRRLFAEGGPDRAVIGVDEPEGLYLAGQLSVAPEDDRVIRISSGQKLERFGWSVFARKGFLAEWRKGRQMASIDLRAMPGLPGAHNHQNACAAYAACRTLGLAPRQIEAALASFAGLPHRSQTVGEKGGVRFVNDSKATNVDSAAKALQAFPKIRWIAGGLGKDGGIVALQPHLGSVVKAYLIGHSARDFALQIGATDHEICETMERAVARAAEEAQPGEVVLLAPAAASFDQYPNFEKRGEDFMEKVKALL
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_GEOTN
Sequence: MKQGIHPAYKKVIVRCACGNEFESGSVKDELRVEICSECHPFFTGKQKFVSAAGRVDKFNKKYGLK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PYRH_HELPY
Sequence: MQAKIKNKRVLVKFSGEALAGDNQFGIDIHVLDHIAKEIKSLVENDIEVGIVIGGGNIIRGVSAAQGGIIRRTSGDYMGMLATVINAVAMQEALEHIGLDTRVQSAIEIKEICESYIYRKAIRHLEKGRVVIFGAGTGNPFFTTDTAATLRAIEIGSDLIIKATKVDGIYDKDPNKFKDAKKLDTLSYNDALIGDIEVMDDTAISLAKDNKLPIVVCNMFKKGNLLQVIKHQQGVFSMVK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_ARTS2
Sequence: MNTQTRETTSMSDAQDKAGTLIEALPWIQRFAGTTMVIKYGGNAMVNDELRRAFAEDVVFLHHVGIHPVVVHGGGPQINAMLSRLGIESEFKGGLRVTTPEAMDVVRMVLTGQVGRELVGLINSHGPYAVGMSGEDGGLLRAVRTGTVVDGEEVDLGLVGEVVGVNPEGIVDILAAGRIPVISTVAPEIADDGSTTGQVLNVNADTAAAAVASALGASKLVILTDVEGLYANWPDKSSLISSLTASELREMLPRLESGMIPKMAACLQAVDDGVERAHIVDGRLPHSMLLETFTTAGIGTQVVPDEETNA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_HALOH
Sequence: MARIAGVDLPRNKRVEIGLTYIYGIGRSTSNKILKVTGIDPDTRVKDLTEAEIAKLREEVDKYQVEGDLRREIRANIKRLMDIGCYRGIRHRKNLPVRGQRTRTNARTRKGPKKTVGVRRAK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: TPM1_DROME
Sequence: MDAIKKKMQAMKVDKDGALERALVCEQEARDANTRAEKAEEEARQLQKKIQTVENELDQTQEALTLVTGKLEEKNKALQNKKKTTKMTTSIPQGTLLDVLKKKMRQTKEEMEKYKDECEEFHKRLQLEVVRREEAESEVAALNRRIQLLEEDLERSEERLGSATAKLSEASQAADESERARKILENRALADEERMDALENQLKEARFLAEEADKKYDEVARKLAMVEADLERAEERAEQGENKIVELEEELRVVGNNLKSLEVSEEKANQREEEYKNQIKTLNTRLKEAEARAEFAERSVQKLQKEVDRLEDDLVLEKERYKDIGDDLDTAFVELILKE
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin-1, isoforms 9A/A/B, Cytoskeletal tropomyosin, Tropomyosin II.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
[Isoform 9A]: Cytoplasm, cytoskeleton.
Protein: SYGB_LIGS1
Sequence: MAHTFLLEIGLEEIPAHVVTPSVNQLVQKTTKFLKEQRIDFDEVIPYSTPRRLTVKVTGLADKQADIEEEAKGPSKKIALDDEGNWSKAAQGFVRGQGVTVDDIFFKELKGTEYVYVKKFIPGKPVSEVLTGMKDVAMDLKFPTMMRWGSNDFEYVRPIKWLVALLDDEVVPFEILDIKTGRTTQGHRFLGEAVDVPSADKYLETLETQKVIADAGVRKAEIRKQIDDLATENNWNIVVDEDLLEEVNNLVEYPTVFAGKFKEEYLQVPNEVLITSMKDHQRFFYVTDKDGNLLPNFVSVRNGNKDYLENVVAGNEKVLTARLEDAKFFYEEDQQHTIADYVERLKKVMFHDKIGTIYEKMERVNLLAKFLGNKLGLSETELKDLDRASMIYKFDLVTGMVGEFSELQGIMGEIYARLQGEDDNVSTAIREEYMPTSSEGELPQSNVGAVLSIADKLDSIQSFFAANMIPSGSNDPYALRRQALGIIRIALDKGWDISLPLLHEAINYAYAEREDLYKNTQPITNVSETDSFVIDRLAQVLSGNKFRRDILDAVVARADMPFIQALQAAQVLSKHAEDDNFKEVIEALTRVTRLAKKAPEFGSDAVIDSTLFENDTEKVLADEFAKVEAGYGDAEMNEKFTILSSLKDSITAYFDATMIMADDEKVKNNRLLQLVKIAELTEDFGSLDKLIVK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_ROSAC
Sequence: MEEFQGYLELYRSQQHDFLYPLIFREYIYALAHDRGLNRSVLLDNVGYDKKSSLLIIKRLISRMYQQNHFLISVNDSNQNKFFGYNKNLYSQMISEGFAVIVEIPFSLRLVSSLKETETVKSYNLRSIHSIFPFFEDKFPHLNYASDVLIPYPIHLEILVQTLRYCVKDPSSLHLLRLFLHEYYNWNTLITPKKSIFAKSNQRLFLLLYNSYVCEYESILLFLRNQSNHLRLTSSGILFERIRFYEKIKYPVKEVFANDFPATLWFFKDPFIQYVRYQGKSILASKDTPLLMNKWKYYLVHFWQCHFYVWSQPGRIHINQLSKHSFDFLGYLSSIRPNISVVRSQLLENSFLMDNAMKKLDTLFPIIPMIGSLAKVKFCNTSGHPISKSSWADSSDSDIIDRFVRIGGNLSHYYSGSSKKKSLYRIKYILRLSCVKTLARKHKSTVRTFLKRLGPKLLDEFFTEEEQIFSLLFPRTSSTLKRFYRGRIWYLDILCINDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HUTH_ACIAC
Sequence: MSAMPTLVLHPGRVTLAELRAIAAGGQRLALDASALAGMRASQATVDRIALEEQVVYGINTGFGKLASTKIAHDRLAELQRNLVLSHSVGTGDPLPDGVVRMVLATKAVSLARGHSGVRPALVDALLALANADVLPVIPAKGSVGASGDLAPLAHLACVLIGEGAAQVGGRIVTGREAMAAVGLEPFVLGPKEGLALLNGTQVSTALALAGLFAAENVFAAGLVSGCLTLEAIKGSVKPFDARIHEARGQAGQIAVAAAVRALLEGSAIDPSHPDCGRVQDPYSIRCVPQVMGACLDNLSHAARVLQIEANAASDNPLVFTDTGEVISGGNFHAEPVAFAADIIALALSEIGAISERRLALLLDTGLSGLPAFLIRDSGVNSGFMIAQVTAAALAAENQCLAHPSSVTSLPTSANQEDHVSMATYAARRLLDMARNTAVIVGIEAMAAAQGMEFDRSLKSSPLIEAQFAAIRGRVAFLEQDRYLAPDIEAMRLWASTSAWPAPLAACLPSFQ
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_BACFR
Sequence: MNFKEGEVLYFNKPLGWTSFKVVGHARYHMCRRMKVKKLKVGHAGTLDPLATGVMIVCTGKATKRIEEFQYHTKEYVATIQLGATTPSYDLEHEIDATYPTEHITRELVEKTLKTFVGEIQQIPPAFSACKVDGARAYDLARKGQEVELKPKLLVIDEIELLECNLPEIKIRVVCSKGTYIRALARDIGEALQSGAHLTGLIRTRVGDVKLEQCLDPAKFAEWIDQQDVEISD
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: GRIK1_HUMAN
Sequence: MEHGTLLAQPGLWTRDTSWALLYFLCYILPQTAPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQTHPTNSTSGTTLSTDLECGKLIREERGIRKQSSVHTV
What is the function of this protein?
Ionotropic glutamate receptor.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse.  The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.  May be involved in the transmission of light information from the retina to the hypothalamus.
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 1, GluK1, Excitatory amino acid receptor 3, EAA3, Glutamate receptor 5, GluR-5, GluR5.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: FMT_STAAM
Sequence: MTKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMTPPPVKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVDLIVTAAFGQLLPESLLALPKLGAINVHASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDNVGTMHDKLSVLGADLLKETLPSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGLSPWPVAYTTMDDTNLKIYDAELVETNKINEPGTIIETTKKAIIVATNDNEAVAIKDMQLAGKKRMLAANYLSGAQNTLVGKKLI
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SYS_XYLFA
Sequence: MLDPTLLRQQLAKLAECLSTVRGFTLDVAALEALESERKRIQVHTQELQSLRNSKSKAIGQARSKGEDVSSLMAEVAAFSDDLKASEIALEEIRTELEKVALGIPNLPQQDVPLGADERDNVEQARWGVPRTFDFSIKDHVELGACHGWLDAESAAKLSGARFTVLRGPIARLHRALAQCMLDLHVRQHGYEEVNVPIIVNADSLYGTGQLPKFEEDMFSTQLGEHRRYLISTSEISLTNLVRNEIIEADRLPLRMAAHSLCFRSEAGSGGRDTRGMIRQHQFEKVELVSVCKPQESEGEHQRMTRCAETVLEMLGLPYRKILLCTGDMGFAATKTYDLEVWLPSQGMYREISSCSNCGDFQARRMQARWRNSVTGKPELVHTLNGSGVAVGRAMIAVMENYQNADGSITVPEVLRPYMDGLSRIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MHQR_BACSU
Sequence: MTEKSLKLFIVLSRAYRSINDHMNKHIHKHGLNPTEFAVLELLYHKGDQPLQQIGDKILLASGSITYVVDKLEQKELLIRKASPTDRRVTFAQITEKGIGLLNDIFPDHAAEIDEMISVLSEEEVEMCTEMLKRVGLNAKQFHNK
What is the function of this protein?
Negatively regulates mhqA, mhqED, mhqNOP, and azoR2 which may contribute to the degradation of aromatic compounds.
What are the official names of this protein?
HTH-type transcriptional regulator MhqR.
Protein: DXR_MYCLE
Sequence: MNNPIEGHAGGRLRVLVLGSTGSIGTQALEVIAANPDRFEVVGLAAGGAQLDTLLRQRAATGVTNIAIADDRAAQLAGDIPYHGTDAVTRLVEETEADVVLNALVGALGLRPTLAALHTGARLALANKESLVAGGSLVLAAAQPGQIVPVDSEHSALAQCLRGGTPDEVAKLVLTASGGPFRGWNAGDLERVTPEQAGVHPTWSMGTMNTLNSASLVNKGLELIEANLLFGIPYDRIEVVVHPQSIVHSMVTFIDGSTIAQASPPDMKLPISLALGWPQRVGGAARACAFTTASTWEFEPLDIDVFPAVELARHAGQIGGCMTAIYDAANEEAAEAFLQGRIGFPAIVATIADVLQRADQWAPQWGEGPATVDDVLDAQRWARERALCAVATASSGKVSDMVLERS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RS7_HELPJ
Sequence: MRRRKAPVREVLGDPVYGNKVVTKFINKMMFDGKKSVAEKIIYKAFNKIEEKSGEKGIEVFEKALERVRPLVEVRSRRVGGATYQVPVEVRASRQQSLSIRWILEATRKRNERMMVDRLANELMDAASDKGAAFKKKEDVHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: YJCD_BACSU
Sequence: MKCARLNDRIIHLHTYSREHYQFLFEEGIKGHLFCSHCGKPVLLRLNIADPPEFIHRQPGDFPACEEACEPKPSKEGKKEDDQESGVIRLPKGKAIAADPSPAVTEWHRPRSIKPGTPFVPKTIEPDTSLFPSVGLNTDQLKAVTETEGPLLVLAGAGSGKTRVLTARAAHMIEHLGIPPENMLLVTFTTKAVAEMKERMANQYGLQPAKVRRIVTGTFHSLFYKILYHSNSAKWNGEHLLKMEWQREQYIKKALYEEGIDEKESPVDQALQQIGFWKNTYVPNERIPLKDEWEKQVYRLYEHYERQKKEHSQFDFDDMASACYELFIERPDLLEQYQSRFTYILIDEFQDINPVQYKIMQMLASPEQNLCCVGDDDQSIYAFRGSNPSFILDFQKDYPGAKTIYLTANYRSTHPIVSSADIVVKKNKNRYAKTLEAARDDIQVPVLFYPYDEEEEATMVVSDIKEKIQNGASPEDFAVLYRTNSGGRAIYERLHQSSIPYTADRGVQSFYSRRIVRQILAYLYASQNEDDTEAIKHLLPALFLKQSALNTLKALSITEDCTMIKALAKLPDLKPFQLDKIKKIVPFFASLRTMKPVEAITFAEGKMGFSEYLKKRGNEGNKLEKGSDDLRDIKVVAKKFKTIPDFLAHVDHMRAAEKNRTDEHGVQLMTIHRSKGLEFKTVYVLGTVDGSIPHDFSLETARKGDEAALEEERRLLYVAMTRAKQHLYLSCPANRRGKTANRSRFLYPLLQKARQPLHH
What is the function of this protein?
May be involved in the generation of recombinogenic substrates for the subsequent action of RecA.
What are the official names of this protein?
Putative ATP-dependent DNA helicase YjcD, DNA 3'-5' helicase YjcD.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_STRPQ
Sequence: MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWKRKKA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MET2_CAEEL
Sequence: MDQQEPSNNVDTSSILSDDGMETQEQSSFVTATIDLTVDDYDETEIQEILDNGKAEEGTDEDSDLVEGILNANSDVQALLDAPSEQVAQALNSFFGNESEQEAVAAQRRVDAEKTAKDEAELKQQEEAEDLIIEDSIVKTDEEKQAVRRLKINEFLSWFTRLLPEQFKNFEFTNPNYLTESISDSPVVNVDKCKEIVKSFKESESLEGLSQKYELIDEDVLVAAICIGVLDTNNEEDVDFNVLCDDRIDDWSIEKCVTFLDYPNTGLNSKNGPLRFMQFTVTSPASAILMLTLIRLREEGHPCRLDFDSNPTDDLLLNFDQVEFSNNIIDTAVKYWDDQKENGAQDKIGRELNDFFHEIESTSAEFKQHFENAVGSRNEIIQLVNEKIPDFDGTEAAVNESFTSDQRTEIINSRAIMETLKAEMKLAIAEAQKVYDTKTDFEKFFVLTVGDFCLARANPSDDAELTYAIVQDRVDAMTYKVKFIDTSQIRECNIRDLAMTTQGMYDPSLNTFGDVGLRVACRQVISSSQFGKKTIWLTGTAAGRRRAHRSDFLIFFDNGTDAYVSAPTMPGEPGYEVASEKKSVFSLKEMIAKMNAAQIAIMVGQPVGKEGNLDYFLTFHWIRQSHRSAYIRDFMKEFPEWPLLKMPVGMRICLYNSLVDRRKKMVTVIGTDRAFAIVRHEAPNPLAPGNRCTDFPCNDRNHQHIDEKIYRGSHRLEGAAHKKHMISTNNNLSQRRKDQLQSQFEPTDMIRSMPERNHQQVVKKKTTGTNQNVASTNDAKSKREIEIRKKNQFLFNKIIVPIPVLTPLENLKAHAQCGPDCLQKMDADPYEARFHRNSPIHTPLLCGWRRIMYTMSTGKKRGAVKKNIIYFSPCGAALHQISDVSEYIHVTRSLLTIDCFSFDARIDTATYITVDDKYLKVADFSLGTEGIPIPLVNSVDNDEPPSLEYSKRRFQYNDQVDISSVSRDFCSGCSCDGDCSDASKCECQQLSIEAMKRLPHNLQFDGHDELVPHYQNRLLSSKVISGLYECNDQCSCHRKSCYNRVVQNNIKYPMHIFKTAQSGWGVRALTDIPQSTFICTYVGAILTDDLADELRNADQYFADLDLKDTVELEKGREDHETDFGYGGDESDYDDEEGSDGDSGDDVMNKMVKRQDSSESGEETKRLTRQKRKQSKKSGKGGSVEKDDTTPRDSMEKDNIESKDEPVFNWDKYFEPFPLYVIDAKQRGNLGRFLNHSCDPNVHVQHVMYDTHDLRLPWVAFFTRKYVKAGDELTWDYQYTQDQTATTQLTCHCGAENCTGRLLKS
What is the function of this protein?
Histone methyltransferase which is required for the mono- and dimethylation of 'Lys-9' of histone H3 (PubMed:20107519, PubMed:22939621).  This increases the efficiency of set-25-mediated trimethylation of histone H3 'Lys-9' (PubMed:22939621).  Involved in the transcriptional repression of lin-3 which is required for the negative regulation of vulval cell fate specification during postembryonic development (PubMed:17634190).  Has a role in blocking checkpoint signaling and mediating the transcriptional silencing of meiotic sex chromosome inactivation; a mechanism which enables checkpoint proteins to distinguish between the partnerless male X chromosome and asynapsed chromosomes thereby shielding the lone X from inappropriate activation of an apoptotic program (PubMed:21909284).  Operates redundantly with set-25 to position chromatin at the nuclear periphery (PubMed:22939621).  Required for small-RNA-induced H3K9 methylation (PubMed:26365259).  Together with set-25, protects and stabilizes repeat-rich genomic regions by suppressing transcription-induced replication stress through methylation of H3K9 (PubMed:27668659).  Together with spr-5, required for transgenerational fertility (PubMed:24685137).
What are the official names of this protein?
Histone-lysine N-methyltransferase met-2.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm.
Protein: PSBN_ZYGCR
Sequence: METATLVAIFISCLLVSFTGYALYTAFGQPSKELRDPFEEHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CENPU_YEAST
Sequence: MDRDTKLAFRLRGSHSRRTDDIDDDVIVFKTPNAVYREENSPIQSPVQPILSSPKLANSFEFPITTNNVNAQDRHEHGYQPLDAEDYPMIDSENKSLISESPQNVRNDEDLTTRYNFDDIPIRQLSSSITSVTTIDVLSSLFINLFENDLIPQALKDFNKSDDDQFRKLLYKLDLRLFQTISDQMTRDLKDILDINVSNNELCYQLKQVLARKEDLNQQIISVRNEIQELKAGKDWHDLQNEQAKLNDKVKLNKRLNDLTSTLLGKYEGDRKIMSQDSEDDSIRDDSNILDIAHFVDLMDPYNGLLKKINKINENLSNELQPSL
What is the function of this protein?
Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis.  Component of the inner kinetochore COMA complex, which connects centromere-associated proteins and the outer kinetochore.  COMA interacts with other inner kinetochore proteins to form the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.
What are the official names of this protein?
Inner kinetochore subunit AME1, Associated with microtubules and essential protein 1, CENP-U homolog, Constitutive centromere-associated network protein AME1.
What is the protein family that this protein belongs to?
Belongs to the CENP-U/AME1 family.