PharMolix/UniProtQA huggingface dataset:
Protein: KDPC_BACCZ
Sequence: MAKKQSILSPIIRITFTFLVLCGLVYPLIITGIAQAVMKDNADGSLIYNDKNEVIGSKLIGQNFTDPRYFHGRVSSIEYKAEASGSNNYAPSNPDLEKRVEKSIEEWKKQNPSVPVTEVPIDLVTNSGSGLDPDISPKAASVQVERISKLTKIPKETLEQLIQDQTEGAALGLFGETRVNVLKLNLELQKLLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NU2C_NAREL
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVMSITALLFRWKEEPIISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDXITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALISITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVSFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLKSNNSIEWSMTVCVIAXTIPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic, NAD(P)H dehydrogenase, subunit 2, NADH-plastoquinone oxidoreductase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ARGB_MYCA1
Sequence: MTPSTEALPTAVKAQVLAEALPWLKQLHGKIVVIKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIPGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVTTDIGLVGDVERVNAAAVLDLIAARRIPVVSTLAPDAEGVVHNINADTAAAALAEALGAEKLLMLTDVEGLYTSWPNRDSLVSEIDTATLSQLLPTLEAGMIPKVEACLRAVSAGVPSAHVIDGRVEHCVLVELFTDAGTGTKVVSS
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_SHEB2
Sequence: MARYLVLAVALLLAACSSTQKKPLADDPFYAPVYPEAPPTKIAATGSIYQDSQASSLYSDIRAHKVGDIITIVLKESTQAKKSAGNQIKKGSDMSLDPIFAGGSNVSIGGVPIDLRYKDSMNTKRESDADQSNSLDGSISANVMQVLNNGSLVIRGEKWISINNGDEFIRVTGLVRSQDIKPDNTIDSTRMANARIQYSGTGTFADAQKVGWLSQFFMSDWWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: THII_SHEPC
Sequence: MKFIVKLYPEIMMKSKPVRMRFTKMLETNIRNVLKKVDEDAKVQRQWDRIMVMVPKHKPELAQAFGERLACIPGIAHVVQVDEYSFESVDDIYQQALPVYRDQIAGKTFCVRVKRTGDHDFNSIDVERYVGGGLNQFTDAIGVRLKNPDVTVNLEIDRDKLYMVTKRIEGLGGFPMATQEDVLSLISGGFDSGVSSYQFIKKGARTHYCFFNLGGAQHEIGVKQVAYHLWKTYGESHKVKFVSVPFEPVVAEILEKIDNGQMGVVLKRMMMRTAARIAERLGIQALVTGESLGQVSSQTLTNLNVIDRCTELLILRPLIAMDKQDIINESRRIGTEDFAKSMPEYCGVISQKPTVKAVLAKVEAEEKKFSEDLIDQIVAQAVTIDIREIAEQMDTRITETETVIAIETNEVVIDIRAPEEEEHKPLNIEGVEVKRIPFFKLATQFADLDKQKTYLLYCERGVMSKLQALYLIEQGYTNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACD17_MYCTU
Sequence: MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPPHEREEFARHWRRALAGAGLVAVSWPTEYGGGGLSPMEQVVLAEEFARAGAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEPEAGSDLASVRTRGVLDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVNAAGHSSFSEVFLTDARTSAGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARDRGLHTDPRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPGAEAAITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYARAATIYAGSSQIQRNVIGERLLGLPKEPRPEVLC
What are the official names of this protein?
Putative acyl-CoA dehydrogenase FadE17.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: O1614_CONPE
Sequence: MNLTCMMIVAVLFLTAWTFVMADDSNNGLANLFSKSRYEMEDPEPSKLEKRKTCQRRWDFCPGALVGVITCCGGLICLGVMCI
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).
What are the official names of this protein?
Mu-conotoxin-like PnMKLT1-014.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHS7_FUSO4
Sequence: MSGFGDFTSICETAPLPLCASVGPTLQATGRTGIEPECYARNIELANTIIFEGAASVMHIVALIMTVIMILHVRSKFTAVGRKEILSFFYLYMLLTAMSLIIDAGVAPPGSDPYPYFVSVQNGLSSAVITCLLINGFVGFQLYEDGTPLSVWMMRISSLAAFAISFLVSLATFKSWAGLGPTNTVGLFVVLYLLNAVQLFVYVAMQILLVTRTLQDRWPLGDIAFGIFFFVAGQVLLYAFSSKICIAISHYLDGLFLATVCNLLGVMMVYKYWDSITKEDLEFSVGTRMNNWEVKELLPEEDRRATVFSEDPYAQSSSYDLPYSPGVARYSAKY
What is the function of this protein?
Chaperone required for the export of the chitin synthase chs3 from the endoplasmic reticulum.
What are the official names of this protein?
Chitin synthase export chaperone.
What is the protein family that this protein belongs to?
Belongs to the CHS7 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RUVC_SHEB5
Sequence: MAIILGVDPGSRITGYGVIQCQGRHQIYLGSGCIRTSSEELPGRLKQIFDGITEIIRQYQPDEFAIERVFMAKNADSALKLGQARGAAIVAATVANLPVAEYSATQIKSAVVGTGRAQKAQVQHMIQQLLKLPAAPQADAADALGVAVCHYHTSQSLIALSGRATARTYGRYR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: YHI2_MYCTU
Sequence: MPCVFCAIIAGEAPAIRIYEDGGYLAILDIRPFTRGHTLVLPKRHTVDLTDTPPEALADMVAIGQRIARAARATKLADATHIAINDGRAAFQTVFHVHLHVLPPRNGDKLSVAKGMMLRRDPDREATGRILREALAQQDAAAQD
What are the official names of this protein?
Uncharacterized HIT-like protein Rv1262c.
Protein: PHT5_PSEPU
Sequence: MAREPIIMNKLNLSIAVGNYVRIRPLVDGEVQIDGVDPIFMLQDPEEIFFRAFRHADYDICELSLSSYSVKTAAGTSPYIAVPVFPSRAFRHTSIYIRNDRGIESAADLKGKRIGVPEYQLTANVWVRLFLEEDHGLKASDVTWVRGGYEETGRLEKIVLKLPADVIVENAPETETLSGMLASGELDAVIGPRAPSCFTQGHPKVSYLYRDPQGAASDWYRALSYSRSCTCWGSGARWPSSTLGYPGPLPKHSRSPSP
What are the official names of this protein?
4,5-dihydroxyphthalate decarboxylase, DHP decarboxylase.
What is the protein family that this protein belongs to?
To P.testosteroni DHP decarboxylase.
Protein: HUTH_CAUVC
Sequence: MTELVLNPGAVPLAEWKAIYRGASARLAESAWPVIAESAAAVQRILAKGEPVYGINTGFGKLASVRIGDADLETLQRNIVLSHAAGVGEPSPVPVIRLMMALKLASLAQGASGVRVETVRMLEEMLVEGLTPVVPCQGSVGASGDLAPLSHMAATMIGVGEIFVGGQRLPAAQALAQAGLEPLTLGPKEGLALLNGTQFSTANALAGLFEAERLFQSALVTGALSTEAAKGSDTPFDPRIHTLRRHVGQIETAAALRALMSASEIRASHLKEDERVQDPYCLRCQPQVMGAALDILRQAATTLATEANCVSDNPLIFPEADEALSGGNFHAEPVAFAADMIALAVCEIGSIAERRIAMLVDPALSGLPAFLTPKPGLNSGFMIPQVTAAALVSENKQRAYPASVDSIPTSANQEDHVSMAAHGARRLLAMVENADAVLGIELLAAAQGCDFHAPLRSSAALEAVRALTRSKVPHLSDDRHFHPDMEAANTLVRSGAVIAAVGALPGVTA
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_PSEPG
Sequence: MVTIRLARGGSKKRPFYHLTVTNSRNARDGRFVERVGFFNPIAAGAEVKLSVNQERVTYWLSQGAQPSERVAQLLKEAAKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SOMA_SALSA
Sequence: MGQVFLLMPVLLVSCFLSQGAAMENQRLFNIAVNRVQHLHLMAQKMFNDFEGTLLPDERRQLNKIFLLDFCNSDSIVSPIDKLETQKSSVLKLLHISFRLIESWEYPSQTLTISNSLMVRNSNQISEKLSDLKVGINLLIKGSQDGVLSLDDNDSQQLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MCRZ_METFV
Sequence: MAYEPQFNPGETKIAENRRKHMNPNYELKKLREIADEDIVRVLGHRSPGESFKTVHPPLEEMDFEEDPMKDIVEPIEGAKQGTRIRYIQFADSMYNAPAQPYDRARTYMWRFRGVDTGTLSGRQVIEMRELDLEKVSKILLETEIFDPARCGIRGATVHGHSLRFDENGLMFDALQRYIYDEDSGHVVYVKDQVGRPLDQPVDMGEPLPEDELKEITTIYRKDNIGMREDEELLEVVNKIHEARTIGGFGMEVFKKDLNKRLGGANE
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase II subunit gamma, MCR II gamma, Coenzyme-B sulfoethylthiotransferase gamma.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase gamma subunit family.
Protein: MIAB_ACTP7
Sequence: MAKLHITTWGCQMNEYDSSKMADLLNSTHGLELTDKPEEADVLLLNTCSIREKAQEKVFSQLGRWKNWKKDKPDLIIGVGGCVASQEGEHIRDRAPFVDIVFGPQTLHRLPEMINKIRGGDRAIVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCSFCVVPYTRGEEVSRPVDDVLFEIAQLAEQGVREVNLLGQNVNAYRGETFDGGICTFAELLRLVAAIDGIDRVRYTTSHPIEFTDDIIEVYRDTPELVSFLHLPIQSGADRVLTMMKRNHTALEYKAIIRKLREVRPNIQISSDFIVGFPGETAEDFEQTMKVIEQVNFDMSFSFIYSARPGTPAADLPDDISEEEKKERLARLQQRINHQAMQFSRAMLGTEQRVLVEGPSKKDIMELTGRTENNRIVNFQGTPDMIGKFVDIKITDVYTNSLRGDVVRTEDEMGLRVVESAASVIARTRKEDDLGVGKYVVNL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_ACTP7
Sequence: MKTYTYSKQDLSFIEQLSQAYCKDPFSYLGLHQAGDVSVIRVFLPEATTVKILSADGQILSEALKIDDSGLFVAQLSQQYSSLNYRLRVGYSLAEIDLEDPYRFTSSLLPMDNWLLAEGTHLRPYEILGAHLKTQEGVSGVHFSVWAPNARRVSVVGDFNYWDGRVNPMRFHAESGIWDIFLPNVEKGALYKFEILDSNGNIRLKSDPYAFASQFRPDTASVVTGLPEKIEVDAKLRHANDPDQPISIYEVHLGSWRRHLENNYWLNYEEIANELIPYVKDMGFTHIELLPITEYPFDGSWGYQPTGLYSPTSRFGSPDDLRTLIRKAHEAGINVILDWVVGHFPTDSHGLTEFDGSHLYEHQDPREGYHQDWNTLIFNYGRHEVFNYLSSNALYWTERFGIDGLRVDAVSSMIYRDYSRKDGEWIPNQYGGRENLEALDFLRRTNRMLKKEGHGAVVIAEESTSFAGITHSPTENGVGFDYKWNMGWMNDTLRYMSLDPIYRQYHHDWMTFGMMYQYSEKFVLPLSHDEVVHGKCSILGKMSGDCWQKFANLRAYYGYMWGYPGKKLLFMGNEFAQGREWNYNESLDWFLLGEQGGGWHKGVLNWVRDLNRTYQKYPALYQLDYDPAGFEWLVVDDWQQSVFAFERKAKNGESVIVVSNFTPVVRHNYRIGVRQDGTYTEILNSDAAYYEGSNVGNYGEIECEAIESHGKPFSIELSIPPLSTIFIACQPKPKEAVEAEQDIVKMAEVAMQKALKPTKKTVSVKAKAHKKAHKNKK
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: COFD_METVS
Sequence: MKITILSGGTGTPKLIQGFKKIIPNKDISVIVNTGEDTYIGDLYLSPDIDTVIYTFSDIINDETWYGLKEDTFFCHEQLKNYGFNEVLKIGDRDRALKMHKTALLKKGIPLSEIVELEKSSLNITSKIYPMSNDLVQSKILIEENGEKLLLKFHDFWIFRKGNANVLDVFYENSNYAKPADGVLRAIEESDFVVIGPSNPITSIGPILSIKEIKEALKEKIVFAVSPIIGENPVSGPTGTLMSAKGYSVDVTGIYGYYKDIVNVMVIDSKDINKKKEIECDVLCIDTIMKTIEDKVNLSKNIVEYYKSKCTY
What is the function of this protein?
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
What are the official names of this protein?
2-phospho-L-lactate transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: RS20_LACJO
Sequence: MPQIKSAIKRVKTNATANKRNAAELSKLRTAVRKFNEAVENDAKDVLDLEVKAARALDKAASKGLISKNKANRDKSRLSKKAANK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: GPDM_MACFA
Sequence: MAFQKAVKGTILVGGGALATVLGLSQFAHYRRKQMNLAYVKAADYISEPVNREPPSREAQLLTLQNTSEFDILVIGGGATGSGCALDAVTRGLKTALVERDDFSSGTSSRSTKLIHGGVRYLQKAIMKLDIEQYRMVKEALHERANLLEIAPHLSAPLPIVLPVYKWWQLPYYWVGIKLYDLVAGSNCLKSSYVLSKSRALEHFPMLQKDKLVGAIVYYDGQHNDARMNLAIALTAARYGAATANYMEVVSLLKKTDPQTGKVRVSGARCKDVLTGQEFDVRAKCVINATGPFTDSVRKMDDKDAAAICQPSAGVHIVMPGYYSPESMGLLDPATSDGRVIFFLPWQKMTIAGTTDTPTDVTPHPIPSEEDINFILNEVRNYLSCDVEVRRGDVLAAWSGIRPLVTDPKSADTQSISRNHVVDISESGLITIAGGKWTTYRSMAEDTINAAIKTHNLKAGPSRTVGLFLQGGKDWSPTLYIRLVQDYGLESEVAQHLAATYGDKAFEVAKMASVTGKRWPIVGVRLVSEFPYIEAEVKYGIKEYACTAVDMISRRTRLAFLNVQAAEEALPRIVELMGRELNWDDHKKQEQLETAKKFLYYEMGYKSRSEQLTDRSEISLLPSDIDRYKKRFHKFDADKKGFITIVDVQRVLESINVQMDENTLHEILNEVDLNKNGQVELNEFLQLMSAIQKGRVSGSRLAILMKTAEENLDRRVPIPVDRSCGGL
What is the function of this protein?
Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M, mtGPD.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y1673_SYNY3
Sequence: MYPLTSDIASITSTQNPLVKQLRQLHQTKGRKQQGQLLLEGTHLLEVALAQGKGFNHGCFTAMWQEKNPVLADRLMAQSVHSYLVSGEVLAKMASTVNPDGVVATLTMDQFWRSPPPHARLGLVLERLQDPGNLGTILRTAAATGVEGIWLTADCVDPTSPKVLRSSAGSSLLLPQQQLQSLPPLLEKFHTQGLQLIATVPQATQTLWEIDFQRPTIVIFGSEGQGLSAPVLELTTHQVAIPQAPQVESLNVAIAVGVMLYEARRQQWAASTPG
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase slr1673.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: GLYA_TRIEI
Sequence: MINANFLADTDPLVAEIIQKEYGRQQDHLELIASENFTSPAVMAAQGSVLTNKYAEGLPSKRYYGGCEFIDEVEQIAIDRAKQLFGAAHANVQPHAGAQANLAVFLTLLKPGDTIMGMDLSHGGHLTHGSPVNISGKWFKAHHYGVNKETEAIDYDQVLELAKKHKPKLLICGYSAYSQIINFEKFRAIADEVGAYLLADIAHIAGLVATGHHPNPVPHCDVVTTTTHKTLRGPRGGLILTRDSELGKKLDKSVFPGTQGGPLEHVIAAKAVAFGEALKPEFKTYSGQVIENAAALATQLQERKLKIVSGGTENHVMLVDLRSVSMTGKKADKLMSGVNITANKNTVPFDPESPFVTSGLRLGSPAMTSRGMKATEFIEIGDIIAERLQNPEDEGIAQKCRERVASLCKAFPLYPHMMAKVPSLV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_PHOPR
Sequence: MSTHAPVITVDGPSGAGKGTLCMLLAEKLGWHLLDSGAIYRVLALAAIHHGVDLESEDVLVPLAAHLDVQFKAEGDLVKVILEGEDVSGELRKEETGMTASKVAALPRVREALLRRQRAFSNAPGLVADGRDMGTVVFPNAIVKIFLDASAEERANRRMNQLQQKGLDVNFGSLLSEIQERDDRDRNRSVAPLRPAEDALVLDSTDMSIEQVTAQAFAYIEQALEQKS
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_METFK
Sequence: MSFKVVIPARYASSRLPGKPLLDIAGKPMVVRVIERSLASGAAEVVVATDHERIQEAVSSYGYDVMMTSADHASGTDRIAEVVQQRGWEDDTIVVNVQGDEPLIDPRLIGEVAGNLSAHAEASMATACHVLHDTPSILNPNIVKVVLDQQGHALYFSRAPIPYPRDAFAANQDIPPGMPIYRHIGIYAYRAGFLRAYAALTPSAIEYFESLEQLRVLWHGYKISVEITEKAPASGVDTEADLAYVRSVVISGESKLL
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_I67A2
Sequence: MASQGTKRSYEQMETGGERQDATEIRASVGRMIGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPSVGKDPKKTGGPIYRRIDGKWMRELILYDKEEIRRVWRQANNGEDATAGLTHIMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTIVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGHDFEREGYSLVGIDPFKLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSGFIRGKKVVPRGKLSTRGVQIASNENVEAMDSSTLELRSRYWAIRTRSGGNTNQQKASAGQISVQPTFSVQRNLPFERATVMAAFVGNNEGRTSDMRTEIIRMMESAKPEDLSFQGRGVFELSDEKATNPIVPSFDMNNEGSYFFGDNAEEYDN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PLPHP_BUCBP
Sequence: MKNIQKNIKKLKQKITNISKKFKINTQKIKLLAVSKNRSVNDIKKAILCGQNSFGENYVQESQPKIKLFNNIEWHYIGQIQSNKAHIIAKNFSWCHTITNKKTAVLLNKYRPYSLPKLNTLIQINIRDNTINIDDDIETIKQLAKTINSLDNLNLRGIMAMPYFKNTYLEQIQSYKYIHLYFDILKKKYTYIDTVSLGTSHDIQAALYSGSTLLRIGSSIFDV
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: END4_CITBB
Sequence: MDLLGAHVSIAGGIHNAVDRGVSSGCGVIQIFTQNSNQWKGKAVSPADAQLFRDKLTASGLSHVVSHDIYLINLAAAPGEVKDKSLIAFKEEMQRCAALGIDKIVMHPGSHTGDGEETGIRRICEAFDQLFAEVPEFTGKVLLENTAGQGTNLGYRFDHLKSIIEGSSYPTRFGVCFDTCHAFASGYPIADRDGYRRTFDEFDSALGIDKLMAFHLNDSKKGLGCKVDRHEHIGAGALGLEPFRFILNDPHFKLVPKFIETPKGDADEMDVVNLKLLRSLVEG
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RK22_THAPS
Sequence: MSNGQSVKAVAKYVRISPHKVRQVLDQIRGRSYQEALMILEFLPYDAGSPIWQVVHSVAANAKNNYNLDKKKLVISEIFADEGPKLKRIRPRAQGRAYKILKPTCHITVVVKSIS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.