PharMolix/UniProtQA huggingface dataset:
Protein: NADD_PELUB
Sequence: MVKPENNLNQKKTKIGILGGTFDPAHKGHLEISKQAKKILELKNIIWAITKQNPFKNTSKTDLKNRIKFAKKIIGKNNFIKVKFYEEKVLSNKTIDLINYLNKDKKFEIYFIMGADNLINFHKWYKWKSIIKKCNLLVFDRQGYKAKSLKSVTYNGVNKNRLSFINFKKVNISSSQLRKI
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: YTOP_BACSU
Sequence: MNQETKALFQTLTQLPGAPGNEHQVRAFMKQELAKYADDIVQDRLGSVFGVRRGAEDAPRIMVAGHMDEVGFMVTSITDNGLLRFQTLGGWWSQVLLAQRVEIQTDNGPVPGVISSIPPHLLTDAQRNRPMDIKNMMIDIGADDKEDAIKIGIRPGQQIVPVCPFTTMANEKKILSKAWDNRYGCGLSIELLKELHGKELPNTLYAGATVQEEVGLRGAQTASHMIKPDLFFALDASPANDMSGDKNEFGQLGKGFLLRILDRTTVMHRGMREFVLDMAETHDIPYQYFVSGGGTDAGKVHISNSGVPSAVIGICSRYIHTNATIIHIDDYAAAKEMLIKLVTACDKQTVDAIKENM
What are the official names of this protein?
Putative aminopeptidase YtoP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M42 family.
Protein: DEOC_MYCBT
Sequence: MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATRLGLSGTRAVLDGLS
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EG5A_PHACH
Sequence: MLKYASIALALATLGVAQQQQWGQCGGIGWTGATTCVAGSVCSVLNPYYSQCIPGAATVTSSSAPSTPTPPAGALPRLGGVNTAGYDFSVATDGSFTGTGVSPPVSQFSHFSSQGANLYRIPFAWQLMTPTLGGTISQSFLSRYDQTVQAALNSGPNVFVIIDLHNYARWNGGIIAQGGPTDAQFQSIWTQLAQKYGSNQRVIFGIMNEPHDIPSISTWVNSVQGAVNAIRAAGATNYLLLPGSSWSSAQAFPTEAGPLLVKVTDPLGGTSKLIFDVHKYLDSDNSGTHPDCTTDNVQVLQTLVQFLQANGNRQAILSETGGGNTSSCESLLANELAYVKSAYPTLAGFSVWAAGAFDTTYVLTVTPNADGSDQPLWVDAVKPNLP
What is the function of this protein?
Secreted manganese dependent endoglucanase that acts by cleaving the beta-1,4-glucose linkage (PubMed:26173955).  Exhibits high activity toward carboxymethyl-cellulose (CMC), barley glucan, and glucomannan (PubMed:26173955).  Displays low activity on larminarin and xyloglucan but does not hydrolyze hemicellulose substrates such as birchwood xylan, arabinoxylan, and arabinan (PubMed:26173955).
What are the official names of this protein?
Manganese dependent endoglucanase Eg5A, Carboxymethyl-cellulase 5A, CMCase 5A, Cellulase 5A, Endo-1,4-beta-glucanase Eg5A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: METAS_SHEB5
Sequence: MPVRIPDHLPAAEVLESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEAVRHKNYDGLIITGAPLGQIDFEDVVYWDHIREIIDWSQEHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTSQHFPLLRGFDDEFFAPHSRFAEMDVEEIRQHPQLQLLAESDEAGAYLVLSRNNRNLFVMGHPEYQKSTLNEEYQRDLSQGLDPNVPQNYYRNDDPKADAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESR
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADDB_STRT2
Sequence: MKLLYTDMSQDLTEILTEQASSYAQKGKRVFYIAPSALSFEKERKVLEYLPQSASFDITVTRFTQMARYFILNTSNPKTQLDDTGLAMIFYKVLLHMGDDELKVYGRLRKDSNFINQLVDLYKELQQANMTVLDLQHLDQVEKQEDLVRIFSAAQDLLLAGDFDNQSKLSAFFKEITSGHLDEALSNTVLVIDGFTRFSAEEEALVALLNDKCHQIVVGTYTSQKAYKANFVYGNVYQASVDFLRTLAQTYKVIPDYVTTDKEGNLSFARISRLLESRHDFSTVDETVTEQDKHALKVWEVVNQKEEVAQVAKSIRQLLADGKRYKDILVLLGDEESYKLHVGQIFRKFDIPYYFGKEESMSSHPLVEFVDSLERIKRYNYRAEDLLNLVKSGLYGGFAQEDLDLFEYYVNFADIKGRHKFLSDFTANSRDKYNLDQINALRSQLIEPLDKFLNSRKQKGSSLLKKLVVFLEAVQLPSQMFELSTKASEAEKEQNEQVWKAFTHILEQVETIFGDESLSVDDFLSILRSGMLACDYRTVPATVDVVNVKKYDLIQPHSAPYVFALGMTQSHFPKVGQNKSLLSDEERSRINEATDEHRRLDIVTQINSKRGHFVAMSLFNAASEQLVLSQPQIINESQDDMSVYLKELLDLGIPLVEKGRNRFEAKGDQIGNYRDLLSTVIALNSSHLDLDLDKETQTFWSVAVRYLRKRLDKDQVLIPKVIDDVTTTKVDDQVMQLVFPEEEPLKLSATALTTFYNNQYLYFLRYVLELEELESIHPDARHHGTYLHRVFERVMGDSSSESFDDKLEKAIAQTNQDQPFEILYTEDQESRFSRQILEDIARSTASVLRDNAAVKVECEEVKFDLLLANSIKITGIIDRVDRLTDGALGVVDYKTGKNVFDIQKFYNGLSPQLVTYLEALRQTYKVDADQLFGAMYLHMQVPQLNLSQIGLEKLAAQAHKELTYKGLFVASETEHLTGGNYDLQKTVTYDKEDLETLLDYNIKLFRSAAEVIRSGNFAINPYTEDGKSVQGDQIKSITHFEADRHMGQARKLLRLPKKGKKEAYLELMAKTEEENQMQVSENTISFPVIDHAVRVDKKDQEDNHVD
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  This subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease RexB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 2 subfamily.
Protein: BTUB_PHOLL
Sequence: MINKKRLLLSTVSIMVISGWNQASAAVESQDSLVVTASRFKQPISSILAPYTVVTRDEIDRWQSNSVADILRRLPGVDIARHGGIGQLSSLFIRGTHASHVLVLMDGIRLNQAGISGSSDLSQIPVSLVQKIEYIRGPRSAVYGSDAIGGVINIITTREKLGTSLNVGIGSHGYQTYDGATQQTLAENTVLTAAANYTYTKGYDVVADGNTGGFRQPDRDGFMSKMLWLGVDQKFNEQVSGFVRAYGYNNRTSYDADINWSYPYARPDTRELYSRHYDMGVRFNQGIYSSQLITSYSHTKDYNFDPQYGRYDKSASLNDSEQYNLQWGNTFQLYQGIVSTGVDFQKQSIEAGTSYIPKSKTVRNTGMYLTAQQQLKDFILEGAIRSDKHSEAGWNTTWQASLGWEFIKDYRLIASYGTAFKAPTLSQMYGFGGNHDLKPEESKQWEGGIEGVTGQLTWRMTVYRNEIEQLIDYANSRYYNIGKAKIKGVEWTGLIDTGMFQHQLTIQYIDPRNSETNEILVRRAKQQVKYQLDWQLYDFDWGLTYQYLGRRYDKDFSTSPAKRVKLGGVSFWDLTVSYPVTSYLTIRARIANLLDKDYETVYGYRIPGREYYLTGSYNF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: AROK_HYDCU
Sequence: MHRESIFLVGPMGAGKSTVGRFLADKLHYQFLDSDQVIEDKTGATIPMIFDIEGESGFRAREKAAIDDLTQQSEIVLATGGGAILNPENRKNLRSRGFVVYLKSSVDSLVQRTRHDRNRPLLQTENPEQVLRKLIEERGPLYEEVADLVIQTEQVSVHRVVKQILDKLAEQKII
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRU_AGACL
Sequence: MAFLKKSLLLVLFLGLVSLSICDEEKRENEDEEEQEDDEQSEEKRGMWGTVFKGIKTVAKHLLPHVFSSQQS
What is the function of this protein?
Has antibacterial activity against Gram-positive bacterium M. luteus NCT C2665 and against Gram-negative bacterium E. coli K12D31.
What are the official names of this protein?
Caerin-regulated peptide, CRP-AC1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNFA_SHEDO
Sequence: MTEYLLLLIGTVLVNNFVLVKFLGLCPFMGVSSKLASAIGMSMATTFVLTLASVLSFLTNEFLLQPFSLEYLRTMSFILVIAVVVQFTEMLVQKTSASLHRALGIYLPLITTNCAVLGVALLNINEDHNFIESAIYGFGAAVGFSMVLILFSAMRERLAAADVPLPFRGGAIAMITAGLMSLAFMGFAGLIK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SIKE1_MOUSE
Sequence: MSCTIEKILTDAKTLLERLREHDAAAESLVDQSAALHRRVAAMREAGAVLPEQYQEDASDVKDMSKYKPHILLSQENTQIRDLQQENRELWVSLEEHQDALELIMSKYRKQMLQLMVAKKAVDAEPVLKAHQSHSAEIESQIDRICEMGAVMRRAVQVDDNQFCKVQERLAQLELENKELRELLSISSESLQVGKESSVAPASQTIK
What is the function of this protein?
Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3.  Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter.  May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and RIGI.  Does not inhibit NF-kappa-B activation pathways (By similarity).
What are the official names of this protein?
Suppressor of IKBKE 1, Suppressor of IKK-epsilon.
What is the protein family that this protein belongs to?
Belongs to the SIKE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG025_VACCC
Sequence: MVNDKILYDSCKTFNIDASSAQSLIESGANPLYEYDGETPLKAYVTKKNNNIKNDVVILLLSSVDYKNINDFDIFEYLCSDNIDIDLLKLLISKGIEINSIKNGINIVEKYATTSNPNVDVFKLLLDKGIPTCSNIQYGYKIKIEQIRRAGEYYNWDDELDDYDYDYTTDYDDRMGKTVLYYYIITRSQDGYATSLDVINYLISHKKEMRYYTYREHTTLYYYLDKCDIKREIFDALFDSNYSGHELMNILSNYLRKQFRKKNHKIDNYIVDQLLFDRDTFYILELCNSLRNNILISTILKRYTVSIQDLLLEYVSYHTVYINVIKCMIDEGATLYRFKHINKYFQKFGNRDPKVVEYILKNGNLVVDNDNDDNLINIMPLFPTFSMRELDVLSILKLCKPYIDDINKIDKHGCSILYHCIKSHSVSLVEWLIDNGADINIITKYGFTCITICVILADKYIPEIAELYIKILEIILSKLPTIECIKKTVDYLDDHRYLFIGGNNKSLLKICIKYFILVDYKYTCSMYPSYIEFITDCEKEIADMRQIKINGTDMLTVMYMLNKPTKKRYVNNPIFTDWANKQYKFYNQIIYNANKLIEQSKKIDDMIEEVSIDDNRLSTLPLEIRHLIFSYAFL
What is the function of this protein?
Plays a role in the inhibition of host immune repsonse by counteracting the action of interferons on early events in the viral replication cycle.
What are the official names of this protein?
Ankyrin repeat protein OPG025.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG025 family.
Protein: PRPX_HORVU
Sequence: MASAEGGGDKYRSFLHGDGEKKTVWRHGAPPNYDLVNKLFEEERTKEWAEGSVEEKVQRLLKTWEMEMVHKVRPEDQKSVNLKNYSASTNGLKPLTREEVMAMGGYNAFLATTLPPEHRIYDPEAESVESATSTFLTAFPRGFAIEVLDVYSSPSAPRIAFKFRHWGYMEGPFKGHPPHGGRVEFFGVCVFHVDEDTKVEKAEFFYERGNFLASFLTAPAASASASGCPVMRGAD
What are the official names of this protein?
Pathogen-related protein.
Protein: FIBR_HEDJA
Sequence: NYLHDTVGRLWGPSRAGLLDGLDWMVGDVQSR
What is the function of this protein?
Plasmin-like serine protease.  Has fibrinolytic and fibrinogenolytic but not plasminogenolytic activity.  Cleaves after Arg and Lys residues.
What are the official names of this protein?
Fibrinolytic enzyme, NJF.
Protein: KAD2_CHAGB
Sequence: MGYLDDEVKRLQGIISNIEGRVQALESRQLGGNQKKTAEEIRMILIGPPGAGKGTQAPKIKEKFNCCHLATGDMLRSQVAKKTTLGREAKKIMDAGGLVSDDIVIGMIKEELDNNKECKGGFILDGFPRTVPQAEGLDKMLRERSQSLQHAVELKIDDQLLVSRITGRLVHPASGRSYHTTFNPPKVHMTDDITGEPLIQRSDDNAEALKKRLATYHKQTAPVVDYYRKTGIWQAIDAAQAPGQVWKSLQAIFDGDKAKAKKAGSGLLSKLTPSS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: TMCAL_MESM1
Sequence: MAIGIIAEYNPFHNGHIYMINYIKNKFPNEEIIVFMSGKYTQRGEIAVASFETRKKYVLEAGVSKVYELPFETSTQAAHIFAQGAIKMLYEYNVDKLIFGSETNDIDLFYKIANTLKNNEQEYNLKLKEFLKQGLGFPNASSLALKSLVGYEIVMPNDILGLEYVKAIVNNNYNIQAYCLKRTINFHSEFTLENFASASYLRTLIYKSEDISKYSPMIFETIPDRIENYYEEFKQKVISTSKEELAKISLISEGLENRFKKIVLEAQDYDSFVNKANSKRYTSSRIKRIMLYILLDIKK
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
Protein: Y551_PSEAB
Sequence: MLKKTLAALALGSALFTAGQAMAADYKIDKEGQHAFIEFRIKHLGYSWLYGRFNDFDGSFTFDEKNPSADKVKVTINTNSVDTNHAERDKHLRSGDFLNVSKNPTATFESTEVKANGDSADITGNLTLNGVTKPVTIKAKLIGQGDDPWGGYRAGFEGSATLKLKDFGIKMDLGPASQEVELLLSVEGIRQ
What are the official names of this protein?
UPF0312 protein PA14_05510.
What is the protein family that this protein belongs to?
Belongs to the UPF0312 family. Type 1 subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: GAL1_MYCTU
Sequence: MTVSYGAPGRVNLIGEHTDYNLGFALPIALPRRTVVTFTPEHTGAITARSDRADGSARIPLDTTPGQVTGWAAYAAGAIWALRGAGHPVPGGAMSITSDVEIGSGLSSSAALIGAVLGAVGAATGTRIDRLERARLAQRAENDYVGAPTGLLDHLAALFGAPKTALLIDFRDITVRPVAFDPDACDVVLLLMDSRARHCHAGGEYALRRASCERAAADLGVSSLRAVQDRGLAALGAIADPIDARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHESMREDFAITTERIDLIAESAVRAGALGARMTGGGFGGAVIALVPADRARDVADTVRRAAVTAGYDEPAVSRTYAAPGAAECR
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNR23_MOUSE
Sequence: MVTFSHVSSLSHWFLLLLLLNLFLPVIFAMPESYSFNCPDGEYQSNDVCCKTCPSGTFVKAPCKIPHTQGQCEKCHPGTFTGKDNGLHDCELCSTCDKDQNMVADCSATSDRKCECQIGLYYYDPKFPESCRPCTKCPQGIPVLQECNSTANTVCSSSVSNPRNWLFLLMLIVFCI
What is the function of this protein?
Receptor for the cytotoxic ligand TRAIL.  Lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis.  May protect cells against TRAIL mediated apoptosis through ligand competition.  Cannot induce the NF-kappa-B pathway.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 23, Decoy TRAIL receptor 1, TNF receptor family member SOB, TNF receptor homolog 1, Tumor necrosis factor receptor p60 homolog 1.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: TF2L1_PONAB
Sequence: MLFWHTQPEHYNQHNSGSYLRDVLALPIFKQEEPQLSPENEARLPPLQYVLCAATSPAVKLHEETLTYLNQGQSYEIRLLENRKLGDFQDLNTKYVKSIIRVVFNDRRLQYTEHQQLEGWRWSRPGDRILDIDIPLSVGILDPRASPTQLNAVEFLWDPAKRASAFIQVHCISTEFTPRKHGGEKGVPFRVQIDTFKQNENGEYTEHLHSASCQIKVFKPKGADRKQETDREKMEKRTAQEKEKYQPSYETTILTECSPWPDVAYQVNSAPSPSYNGSPNSFGLGEGNASPTHPVEALPVGSDHLLPSASIQDAQQWLHRNRFSQFCRLFASFSGADLLKMSRDDLVQICGPADGIRLFNAIKGRNVRPKMTIYVCQELEQNRVPLQQKRDGSGDSNLCVYHAIFLEELTTLDLIEKIANLYSISPQHIHRVYRQGPTGIHVVVSNELRAMTATTSS
What is the function of this protein?
Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (By similarity).  With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity).  Required for normal duct development in the salivary gland and kidney (By similarity).  Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity).  Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity).  Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity).  JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity).  Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity).  Modulates the placental expression of CYP11A1 (By similarity).
What are the official names of this protein?
Transcription factor CP2-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the grh/CP2 family. CP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARD1_SCHPO
Sequence: MDIRPARISDLTGMQNCNLHNLPENYQLKYYLYHAISWPMLSYVATDPKGRVVGYVLAKMEEEPKDGIPHGHITSVSVMRSYRHLGLAKRLMVQSQRAMVEVYGAKYMSLHVRKSNRAAIHLYRDTLQFDVQGIESKYYADGEDAYAMHKDFSTLKFDTPETNDELAKTVQSLALNN
What is the function of this protein?
Catalytic component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala.  N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover.
What are the official names of this protein?
N-terminal acetyltransferase A complex catalytic subunit ard1, NatA complex subunit ARD1.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ARD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GDX_YERPS
Sequence: MAWIILVIAGLLEVIWAIGLKYSHGFSRLTPSIITLVAMAASVFLLAYAMKSLPAGTAYAVWTGIGAVGTAILGIVLLGESASLARILSLGLILAGIIGLKLAS
What is the function of this protein?
Guanidinium ion exporter.  Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons.
What are the official names of this protein?
Guanidinium exporter.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RBFA_STRU0
Sequence: MANHRIDRVGMEIKREVNAILQKKVRDPRVEGVTITEVQMLGDLSAAKVYYTVMSDLASDNQKAQLGLEKATGTIKRELGKNLTMYKIPDLIFEKDNSIAYGNKIDQLLRALDKKS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBM38_HUMAN
Sequence: MLLQPAPCAPSAGFPRPLAAPGAMHGSQKDTTFTKIFVGGLPYHTTDASLRKYFEGFGDIEEAVVITDRQTGKSRGYGFVTMADRAAAERACKDPNPIIDGRKANVNLAYLGAKPRSLQTGFAIGVQQLHPTLIQRTYGLTPHYIYPPAIVQPSVVIPAAPVPSLSSPYIEYTPASPAYAQYPPATYDQYPYAASPATAASFVGYSYPAAVPQALSAAAPAGTTFVQYQAPQLQPDRMQ
What is the function of this protein?
(Microbial infection) Essential factor for the splicing of the pre-mRNAs of human parvovirus B19 (B19V) and for the expression of B19V 11-kDa protein, which enhances viral replication.
What are the official names of this protein?
RNA-binding protein 38, CLL-associated antigen KW-5, HSRNASEB, RNA-binding motif protein 38, RNA-binding region-containing protein 1, ssDNA-binding protein SEB4.
What is the protein family that this protein belongs to?
Belongs to the RBM38 family.
Protein: NFUA_SHEB8
Sequence: MITISDAAQAHFVKLLADQPEGTHIRVFVISPGTSQAECGVSYCPPDAVESDDIEIEFTGFNAMVDEKSAPFLEDATIDFVTDQLGSQLTLKAPNAKMRKVSGDAPLVERIEYVIQSEINPQLAGHGGNIMLVEITKEGVAVLQFGGGCNGCSQVDITLKDGIEKQLLDMFPGELTGVRDVTDHQHGEHSYA
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: LEUD2_PYRAB
Sequence: MITTGRVWKFWDNVSTDEITPGRYNLTKDPQELARIAFIEVRPEFAEKVRRGDVVVGGKNFGIGSSRESAALALKAAGVSGIIAKSFGRIFYRNAVNLGIPLLIGDTDELEDGDVITVNWETGEVRKNGQTLQFEPLPGFLLEIVREGGILEFIRRRGDLCIG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit 2, Alpha-IPM isomerase 2, IPMI 2, Isopropylmalate isomerase 2.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: MSHB1_SACEN
Sequence: MTLTAPPRLLLVHAHPDDETLWTGGTIARYAARGVQVVVVTCTLGEEGEVIPDNLRGLAADQADQLGGYRVGELRSACAALRVADQRFLGGVGRWRDSGMLWEKPGQASALPDAHPRAFAVGDADEQADALEELLREFRPQVVVTYAADGGYGHPDHIRAHEVTMAAAAKVPDVLRVFHAVPSQGVVKEGLAALAEAEGMPFELPEPHELPGVPDERITTVVDVGEHLPAKISALRAHGTQVKMWLEQWNNGAGVAAYALSNGVAQPVVNTEHYVLATGDQQGCETDLFGGLGVSGTEPVGAR
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 1, GlcNAc-Ins deacetylase 1, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 1.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: PELO_METS3
Sequence: MKIVKQDKKEGIVTLVPETLDDLWHLSHIVEVGDSVSSKTTRRIQDNTGDKLRSDRGVKKTFTLRIDVENITFHIFTGKLRLTGVITKGPEDLIPLGSHHTVEVKLNTPITIKKEKWANWALKRLNQAIEASKKLAAIIVLLEDDTATLGLMRQFGIEYYGPIKGSVSGKRIVDKNRSKAIAQFYEKVIESVNKFHDIQNIVVAGPGFVKNDFYDYIKNKHKDLADKAIIESTGSGGRVGIHEVLKKGTVEKLTVENRVASEMVAINNLLEEIGKNSSKVAYGEKETVKAINLGAVKQLLVLDSAVAINDMGNLMDMVENMNGEVMVISSQHEGGEQLKGLGSMAAILRYEIA
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FER1_ASCSU
Sequence: MMVKQEIVQTGRAQELRCQGYDALKRTSYEFTKHAQPLPNGGFLLCNLEACSYSIQGCGFSPTFALESSEGSVDWRETLILSPKPKLFFLLCREGGPAVHLLSVSSYGDRCKSGEARLRTWHLSCSRCGVALLPSGA
What are the official names of this protein?
Putative FERT-1 protein.
Protein: 2SS2_BRANA
Sequence: MANKLFLVSATLAFFFLLTNASIYRTVVEFDEDDATDSAGPFRIPKCRKEFQQAQHLRACQQWLHKQAMQSGGGPSWTLDGEFDFEDDMENPQGPQQRPPLLQQCCNELHQEEPLCVCPTLKGASKAVKQQIQQQGQQQGKQQMVSRIYQTATHLPKVCNIPQVSVCPFQKTMPGPSY
What is the function of this protein?
The small, basic, water-soluble napins are one of the two major kinds of storage proteins synthesized in the seed during its maturation.
What are the official names of this protein?
Napin-2, 1.7S seed storage protein.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.