PharMolix/UniProtQA huggingface dataset:
Protein: CDK6_MOUSE
Sequence: MEKDSLSRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTSEEGMPLSTIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDIIGLPGEEDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYGALNHPYFQDLERYKDNLNSHLPSNQSTSELNTA
What is the function of this protein?
Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition.  Phosphorylates pRB/RB1 and NPM1.  Interacts with D-type G1 cyclins during interphase at G1 to form a pRB/RB1 kinase and controls the entrance into the cell cycle.  Involved in initiation and maintenance of cell cycle exit during cell differentiation; prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types (e. g.  erythroid and hematopoietic cells).  Essential for cell proliferation within the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles.  Required during thymocyte development.  Promotes the production of newborn neurons, probably by modulating G1 length.  Promotes, at least in astrocytes, changes in patterns of gene expression, changes in the actin cytoskeleton including loss of stress fibers, and enhanced motility during cell differentiation.  Prevents myeloid differentiation by interfering with RUNX1 and reducing its transcription transactivation activity, but promotes proliferation of normal myeloid progenitors.  Delays senescence.  Promotes the proliferation of beta-cells in pancreatic islets of Langerhans (By similarity).  May play a role in the centrosome organization during the cell cycle phases.
What are the official names of this protein?
Cyclin-dependent kinase 6, CR2 protein kinase, CRK2, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell projection, ruffle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized to the ruffling edge of spreading fibroblasts. Kinase activity only in nucleus (By similarity). Present in the cytosol and in the nucleus in interphase cells and at the centrosome during mitosis from prophase to telophase (By similarity). Localized to the cytosol of neurons and showed prominent staining around either side of the nucleus.
Protein: SNR40_MOUSE
Sequence: MIEQQKRKGPELPLVPVKRPRHELLLGAAGAGPGAGPQQATPGALLQAGPPRCSSLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDDGTVKLWDIRKKAAVQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRVLYKLPGHAGSINEVAFHPDEPIILSASSDKRLYMGEIQ
What is the function of this protein?
Required for pre-mRNA splicing as component of the activated spliceosome.  Component of the U5 small nuclear ribonucleoprotein (snRNP) complex and the U4/U6-U5 tri-snRNP complex, building blocks of the spliceosome.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).
What are the official names of this protein?
U5 small nuclear ribonucleoprotein 40 kDa protein, U5 snRNP 40 kDa protein, WD repeat-containing protein 57.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS14Z_CLOBL
Sequence: MARKALIEKWNKTPKHSTRAYTRCRICGRPHAVLKKYGICRICFRELAYKGEIPGCKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: NUD11_BOVIN
Sequence: MKCKPNQTRTYDPEGFKKRAACLCFRSEREDEVLLVSSSRYPDRWIVPGGGMEPEEEPGGAAVREVFEEAGVKGKLGRLLGNFEQNQDRKHRTYVYVLTVTEILEDWEDSVSIGRKREWFKVEDAIKVLQCHKPVHAEYLQKLKLGGSPTNGNSVAPSPPEGDP
What is the function of this protein?
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction.  Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates.  The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A.  Also able to hydrolyze 5-phosphoribose 1-diphosphate.
What are the official names of this protein?
Diphosphoinositol polyphosphate phosphohydrolase 3-beta, DIPP-3-beta, DIPP3-beta, Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta, Diadenosine hexaphosphate hydrolase (AMP-forming), Nucleoside diphosphate-linked moiety X motif 11, Nudix motif 11.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. DIPP subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_STRS7
Sequence: MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLVAENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: THRC1_ARATH
Sequence: MASSCLFNASVSSLNPKQDPIRRHRSTSLLRHRPVVISCTADGNNIKAPIETAVKPPHRTEDNIRDEARRNRSNAVNPFSAKYVPFNAAPGSTESYSLDEIVYRSRSGGLLDVEHDMEALKRFDGAYWRDLFDSRVGKSTWPYGSGVWSKKEWVLPEIDDDDIVSAFEGNSNLFWAERFGKQFLGMNDLWVKHCGISHTGSFKDLGMTVLVSQVNRLRKMKRPVVGVGCASTGDTSAALSAYCASAGIPSIVFLPANKISMAQLVQPIANGAFVLSIDTDFDGCMKLIREITAELPIYLANSLNSLRLEGQKTAAIEILQQFDWQVPDWVIVPGGNLGNIYAFYKGFKMCQELGLVDRIPRMVCAQAANANPLYLHYKSGWKDFKPMTASTTFASAIQIGDPVSIDRAVYALKKCNGIVEEATEEELMDAMAQADSTGMFICPHTGVALTALFKLRNQGVIAPTDRTVVVSTAHGLKFTQSKIDYHSNAIPDMACRFSNPPVDVKADFGAVMDVLKSYLGSNTLTS
What is the function of this protein?
Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.
What are the official names of this protein?
Threonine synthase 1, chloroplastic, Protein METHIONINE OVER-ACCUMULATOR 2.
What is the protein family that this protein belongs to?
Belongs to the threonine synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GUMH_KOMXY
Sequence: MNSKKRGDETLKVLHICRQFSPSVGGLEDSLLNLARSQRQRLGIDAEVLTLDTVFGRPGKLPHRDVVDGIPVTRLAWRGSTKYPLAPQVLRHIGGFDLLHVHAIDFFFDFLAWTWPLHRKTMIASTHGGFFHTGALRRIKEIWFRTITPISVRAYKKIVACSYSDADLFRHVAAGRLITIENGINQTRFRDAASRTPNRTILAFGRFAVHKRLKLLFQLVALLRAYNSGWNIIVAGQDSNLTADDLRAQARACGIEDSLRIVSGPSDAELRGLMGEASFFGCLSAHEGFGLAAVEAMSAGLVPILSNITPFARLMQQGAAGVMVNPDNLAPGAREAEDMAAALPETADALRARNMDVASRYDWHSVAHEYARLYQQVLGRALPEANMAAAGAE
What is the function of this protein?
Involved in the biosynthesis of the exopolysaccharide acetan, a water-soluble polysaccharide involved in production of bacterial cellulose (BC).
What are the official names of this protein?
GDP-mannose:cellobiosyl-diphosphopolyprenol alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: GSX2_MOUSE
Sequence: MSRSFYVDSLIIKDSSRPAPSLPESHPGPDFFIPLGMPSPLVMSVSGPGCPSRKSGAFCVCPLCVTSHLHSSRPPAGAGGGATGTAGAAVAGGGVAGGTGALPLLKSQFSPAPGDAQFCPRVSHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQHHAPVCAATTYNMSDPRRFHCLSMGGSDTSQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGASRNNHTSCKCVGSQAHYARSEDEDSLSPASANEDKEISPL
What is the function of this protein?
Transcription factor that binds 5'-CNAATTAG-3' DNA sequence and regulates the expression of numerous genes including genes important for brain development (PubMed:7619729).  During telencephalic development, causes ventralization of pallial progenitors and, depending on the developmental stage, specifies different neuronal fates.  At early stages, necessary and sufficient to correctly specify the ventral lateral ganglionic eminence (LGE) and its major derivatives, the striatal projection neurons.  At later stages, may specify LGE progenitors toward dorsal LGE fates, including olfactory bulb interneurons (PubMed:19709628).
What are the official names of this protein?
GS homeobox 2, Genetic-screened homeobox 2, Homeobox protein GSH-2.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR14_ANTAG
Sequence: MAKKSLIQREKKREKLKQKYQAFRKYLKEEMSQTLSIDKKWEIQKQLQSLPRNSTPTRIHRRCFLTGRPRANYRDFNLSRHILREMIHACLLPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ZAPD_ECOL5
Sequence: MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDSENGQVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: Y383_STRPC
Sequence: MRKSFYSWLMTQRNPKSNEPVAILADLVFDDTTFPKHTNDFELISRYLEDQASFSFNLGQFDEIWEDYLAH
What are the official names of this protein?
UPF0346 protein MGAS9429_Spy0383.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: RNH2_METCA
Sequence: MASLVAGIDEVGRGCIAGPVIAAAVIFAPGQDTHGLADSKRLRPDRRLVLAGRICSESLAWAVGRAEVSEIDQLNILRATHLAMCRAVAALPVLPDWVRVDGNRYPPLDCPGEAIVGGDASVAEIAAASILAKVFRDREMEVLDRLCPGYALGVHKGYPTRLHIDRLASRGASFFHRRSFAPVRAVIDRSSAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_LACLS
Sequence: MAVTMYYEEDVEVAALAGKKIAVIGYGSQGHAHAQNLRDSGHDVIIGVRQGKSFDRAKEDGFETFEVGEAVAKADVIMVLAPDELQQSIYEEDIKPNLKSGSALGFAHGFNIHFGYIEVPEDVDVFMVAPKAPGHLVRRTFTEGFGTPALFVSHQNATGHAREIAMDWAKGIGCARVGIIETTFKEETEEDLFGEQAVLCGGLTALVEAGFETLTEARYAGELAYFEVLHEMKLIVDLMYEGGFTKMRQSISNTAEFGDYVTGPRIITDEVKKNMKLVLADIQSGKFAQDFVDDFKAGRPKLTAYREAAKNLEIEKIGAELRKAMPFTQSGDDDAFKIYQ
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RSMH_MYCMM
Sequence: MHVRAPWSLPEPTLAYFPNARFVPSDRDLGAGALRLVGEDCPAPTRGGVAVADGPTEPGFNDFHHVPVLAQRCVELLRPALTRHHADGSEAVLVDATIGAGGHAERFLTELPGLRLIGLDRDPSALEIVRTRLARFADRVTLVHTRYDGLASALTELGYGAAQSIDGALFDLGVSSMQLDQAERGFAYSKDAPLDMRMNPQSALSAADIINTYDEAALADILHRYGEERFARRIAARIIRRRADKPFTTTAELVALLYEAIPAAARRTGGHPAKRTFQALRIAVNDELGSLRSAIPAAMDALAVGGRIVVMAYQSLEDRIVKRVFADAVASRTPMDLPVELPGHGPRFRSLTHGAERADAAEVERNPRSAPVRLRALERLELEALPRQGTGKGES
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_CLOPE
Sequence: MRILGLDIGSKTIGVAVSDPLGWTAQGVTTIKRDCYTKDVEAVMKICKEYGVETIVAGMPKNMNGTIGPSGEMVKNLCEQIEKSFDGKIEFWDERLTTVAAHRAMLEADLSRAKRKKIVDKIAATYILQGYLDRISK
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_BACFR
Sequence: MKIKVGFGFDVHQLVEGRELWLGGILLEHEKGLLGHSDADVLVHAICDALLGAANMRDIGYHFPDNAGEYKNIDSKILLKKTVELIAAKGYQIGNIDATICAERPKLKAHIPSMQQVLAEVMGIDADDISIKATTTEKLGFTGREEGISAYATVLINRV
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: YAII_SALNS
Sequence: MTIWVDADACPNVIKEILYRAAERMQLPLILVANQALRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEVLEKGAAALNPRGERYSDATIRERLTMRDFMDTLRASGVQTGGPNTLSPRDRQHFAAELDKWWLESQRKK
What are the official names of this protein?
UPF0178 protein YaiI.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: SYR_NOSP7
Sequence: MNATQEKLKVQLEQALVAAFGADFAGVDPILVSASNPKFGDYQANVALSLSKKLGKQPRAIAGAIVEKLDVSEICEPPEIAGPGFINLKLKTAYLEAQLNDIQADPRLGVPAAKTPKRENVDFSSPNIAKEMHVGHLRSTIIGDSIARILEFQGHDVLRLNHVGDWGTQFGMLIAYLREVYPDALTTANALDIGDLVSFYRKAKQRFDTDTAFQETARQEVVRLQAGAEDTLHAWKLLCEQSRREFQVIYELLDIKLTERGESFYNPLLSGIVEDLEKSGLLVENQGAKCVFLEGFTNREGEPLPLIVQKSDGGYNYATTDLASLRYRIQQDQAKRIIYVTDAGQGNHFAQFFQVARKAGWIPDDVELVHVPFGLVLGEDGKKFKTRSGDTVRLRDLLDEAVSHAHADLKTRLQKEERQETEEFINEVARVVGISAVKYADLSQNRTSNYIFSYDKMLDLKGNTAPYMLYVYARIHGISRKGDINFKELGNNAVLLQHETELALAKYLLQLDEVISSVEQDLLPNRLCEYLFELSQKFNQFYDRCSILQAEEPQRTSRLVLCDLTARTLKLGLSLLGIQVLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_CROS8
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFSALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TRUD_XANOR
Sequence: MSETSLLPRAHGAAVLSAAMRSTPDDFQVDELPAFEPSGEGEHLLLTVCKRGQNTAYIAKKLAHWAGIAEMGVGYAGLKDRHAVTTQRFSVHLPKRIAPDIAALDDAQMQVIDSTWHNRKLQRGALHGNGFVLTLRQVHGERDAVEERLQAIAARGIPNWFGEQRFGRDGGNVAAALVMFGYVQAADGTLAPAPTSRRRLRNDQRSMLLSAARSALFNRVLTARVEQDSWDSALEGEAWMLDGSRSVFGPEPWSDALAERLACFDIHPSGPLWGAGALRSTDQAAAVEQGALSDPQSEALRQGLEAAGLKQERRALRLRPQGLDYRWLEAQTLQLEFALPPGCYATAVLWELGEVTDAGRFDAGVRSDE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: ALDO4_ORYSJ
Sequence: MTKVVAPVERVVFELNGERQEVAAADVEPSTTLLEFIRTRTPFRGPKLGCGEGGCGACVILIAKYNPKTDEVTEFNVNSCLTLLYSIHFCSIITTEGLGNTKDGFHSIQKRMSGFHASQCGFCTPGMCMSIFSSLVNADKSKKPAPPKGFSKLSISEAERSFSGNMCRCTGYRPIVDACKSFESDVDLEDLGLNIFWKKGDKHPDPTKLPSYTLGGGICTFPDFLKSEIKSSLDFNDASISGPREGWYCPKSIKQYYKLVNSGLFSESSVKVVVGNTSTGVYKDQDLYDKYIDIAGIPELSAIVRKDKGIEIGAATSISRTIEILNQESELTSSPNGSVVFRKLAEHMSKVASPFVRNTASIGGNIILAHKYPFRSDIATILLGAAATVNLQVSSKTLHVNLEQFLEQPPLDHSTLLLSIFIPHWASDCKKEHTLVFETYRAAPRPLGNAVSYVNSAFLGHVSLDKSSGDNILSNLHLAFGAYGTKHAIRARKVEEYLTGKILSASVVLEAIRLLRETIVPVEGTTHPEYRVSVAVGFLFSFLSPLCKGVIESGKTLSISEDLVDTDNVHNKPLSSRRETLSDDEYTPVGDPIKKYKVEVQASGEAIYVDDIPAPKNCLYGEFIYSTQPLANVKSIKFKPSLASKKIITVVSAKDIPTGGRNIGSTFWFGDEEPLFGDPIAEFAGQVLGVVIAETQPYADMAAKQAVVEYTTDGLKAPILTVEQAVQSNSYFQVPPERAPKQVGDFSNGMAEADHKIMSEEVKLSSQYYFYMETQTALAIPDEDNTMTVYSSSQFSELAQNVISKCLGIPFNNVRVITRRAGGGFGGKVVRSLHVRI
What are the official names of this protein?
Probable aldehyde oxidase 4, AO-4.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
Protein: INO80_VANPO
Sequence: MSLAKLLNNDDDDNNINLPNINVNNTNTNDTSSSIVTNTHTTNTTTNLQKEKFLNKLNNDFNLLNKRDNLELNYQDWKFLNYQEFELLNEWNQQSKEWNNSIKNFEYLYSLMKKYKSEWENYLTLKSSDKYLKNVVNDCLINSNTNNLKSKSKLKTDTKTKAKSKSKSKLKLKSNSDAKVKSKSSNAKAKAKTKSVSTQQKRKRTTSIKNLLEKEDSALTSLDDMDEIDDVNEILNNDNNDEITQNSKDLSTTTATEKKLNTKTSPSKKRKDEVRVAMKKPMTSTPNVKTENKSKQKSNKKNIDADDNTYDDNNLINGKDTEELDDIEKAKDLEDNTDIEIEGTNENEDEDEDEDEDEDEDEEDEEEGEEEEEEEEDEEGVINMIENEDDEDYFAPGKKSGRQNASKVAGEPAAPVPKTPTTIHSDRERIVRELIKMCNKNKNKKSRKRRFTNSIVTDYNPEENKLIVKVTLKQYHVRKLKKLINDAKKLREEEEMKLKKSLMKEAENAEELEGPSSKKKKLNSGTAQNENGGEQNSEFIQNTHDLPTYGMQMTLKEAKAIKRHYDNTFFTILKDLARKDSAKMARLVQQIQSIRATNFKKNSSVCAREARKWQQRNFKQVKDFQTRARRGIREMLNYWKKNEREERDLKKKAEKVAMEQARKEEEDRENVRQAKKLNFLLTQTELYSHFIGSKIKTNELEGNMKDDEFDENEDNLMNNIDLDSTSSVKTDFKTIDFDNEDDDELRRKAAQNASNVLQKSREKTKKFDNDTSNGEELNFQNPTSLGEVVIEQPSILACTLKEYQLKGLNWLANLYDQGINGILADEMGLGKTVQSISVLAHLAEKYNIWGPFLVVTPASTLHNWVNEISKFVPQFKILPYWGNSNDRKILRRFWDRKNLRYNKDSPFHVMITSYQMVVSDTSYLQKMKWQYMILDEAQAIKSSQSSRWRNLLSFHCRNRLLLTGTPIQNNMQELWALLHFIMPSLFDSHDEFNDWFSKDIESHAEANTKLNQQQLRRLHMILKPFMLRRVKKNVQSELGDKIEIDVMCDLTQRQAKLYQILKSQMSTNYDVIENAAGDDDTGSDQNMINAVMQFRKVCNHPDLFERADVDSPFSFSIFGKSSSLSRDNEPLVDILYSTRNPITYHLPRLIYNDLILPNYENDLGLKNKLLNYTFSIFNNESTCKEISRVTGLTYGEIKRVVHRDLLMNAIHLKEPYSRQTFLEKISVIEDNDKTFSDMNFKSNLKLIERSAKLDALSRVTSTGVLNSLLNIKEQVFDNEYYNAISRSYHPNVSSSPVSIQVLGNRHFSIQQEEELFKPVISKALSEIPASTQYNMAVEKKIPLHDFPVSGLYPSPLNKSFSSYISMPSMDRFITESAKLKKLDELLVELKKGDHRVLIYFQMTKMMDLMEEYLTYRQYSHIRLDGSSKLEDRRDLVHDWQTRPDIFIFLLSTRAGGLGINLTAADTVIFYDSDWNPTIDSQAMDRAHRLGQTRQVTVYRLLIRGTIEERMRDRAKQKEHVQQVVMEGKTLQKDVKTIESGGDVKAAAAASTALTTN
What is the function of this protein?
ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
What are the official names of this protein?
Chromatin-remodeling ATPase INO80.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSDB_THIK1
Sequence: MRQFIPMRRVLAVATLGALFWAAPASWAAAPPEAASCIACHGAGGMGNPAAGYPRLAGLPEQYLADQLRYFADGARNNAVMSGMAKPLSAAQVTALATYYSKLKPSGKPAPMPTGAAAAEGERLALRGDWEKGIPACIRCHGPGAVGVGENFPALVGQSAAYIEAQIKAWKDGSRSGDPLGLMHTVALRMTDAQTQAVAQWLAAQPLSPTKSASAKH
What is the function of this protein?
Acts as an electron acceptor for the thiosulfate dehydrogenase TsdA.
What are the official names of this protein?
Thiosulfate dehydrogenase electron acceptor.
Protein: SCN2A_MOUSE
Sequence: MAQSVLVPPGPDSFRFFTRESLAAIEQRIAEEKAKRPKQERKDEDDENGPKPNSDLEAGKSLPFIYGDIPPEMVSEPLEDLDPYYINKKTFIVLNKGKAISRFSATSALYILTPFNPIRKLAIKILVHSLFNVLIMCTILTNCVFMTMSNPPDWTKNVEYTFTGIYTFESLIKILARGFCLEDFTFLRDPWNWLDFTVITFAYVTEFVNLGNVSALRTFRVLRALKTISVIPGLKTIVGALIQSVKKLSDVMILTVFCLSVFALIGLQLFMGNLRNKCLQWPPDNSTFEINITSFFNNSLDWNGTAFNRTMNMFNWDEYIEDKSHFYFLEGQNDALLCGNSSDAGQCPEGYICVKAGRNPNYGYTSFDTFSWAFLSLFRLMTQDFWENLYQLTLRAAGKTYMIFFVLVIFLGSFYLINLILAVVAMAYEEQNQATLEEAEQKEAEFQQMLEQLKKQQEEAQAAAAAASAESRDFSGAGGIGVFSESSSVASKLSSKSEKELKNRRKKKKQKEQAGEEEKEDAVRKSASEDSIRKKGFRFSLEGSRLTYEKRFSSPHQSLLSIRGSLFSPRRNSRASLFSFKGRVKDIGSENDFADDEHSTFEDNDSRRDSLFVPHRHGERRPSNVSQASRASRGIPTLPMNGKMHSAVDCNGVVSLVGGPSALTSPVGQLLPEGTTTETEIRKRRSSSYHVSMDLLEDPTSRQRAMSMASILTNTMEELEESRQKCPPCWYKFANMCLIWDCCKPWLKVKHVVNLVVMDPFVDLAITICIVLNTLFMAMEHYPMTEQFSSVLSVGNLVFTGIFTAEMFLKIIAMDPYYYFQEGWNIFDGFIVSLSLMELGLANVEGLSVLRSFRLLRVFKLAKSWPTLNMLIKIIGNSVGALGNLTLVLAIIVFIFAVVGMQLFGKSYKECVCKISNDCELPRWHMHDFFHSFLIVFRVLCGEWIETMWDCMEVAGQTMCLTVFMMVMVIGNLVVLNLFLALLLSSFSSDNLAATDDDNEMNNLQIAVGRMQKGIDFVKRKIREFIQKAFVRKQKALDEIKPLEDLNNKKDSCISNHTTIEIGKDLNYLKDGNGTTSGIGSSVEKYVVDESDYMSFINNPSLTVTVPIAVGESDFENLNTEEFSSESDMEESKEKLNATSSSEGSTVDIGAPAEGEQPEAEPEESLEPEACFTEDCVRKFKCCQISIEEGKGKLWWNLRKTCYKIVEHNWFETFIVFMILLSSGALAFEDIYIEQRKTIKTMLEYADKVFTYIFILEMLLKWVAYGFQMYFTNAWCWLDFLIVDVSLVSLTANALGYSELGAIKSLRTLRALRPLRALSRFEGMRVVVNALLGAIPSIMNVLLVCLIFWLIFSIMGVNLFAGKFYHCINYTTGEMFDVSVVNNYSECQALIESNQTARWKNVKVNFDNVGLGYLSLLQVATFKGWMDIMYAAVDSRNVELQPKYEDNLYMYLYFVIFIIFGSFFTLNLFIGVIIDNFNQQKKKFGGQDIFMTEEQKKYYNAMKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMTNILYWINLVFIVLFTGECVLKLISLRHYYFTIGWNIFDFVVVILSIVGMFLAELIEKYFVSPTLFRVIRLARIGRILRLIKGAKGIRTLLFALMMSLPALFNIGLLLFLVMFIYAIFGMSNFAYVKREVGIDDMFNFETFGNSMICLFQITTSAGWDGLLAPILNSGPPDCDPEKDHPGSSVKGDCGNPSVGIFFFVSYIIISFLVVVNMYIAVILENFSVATEESAEPLSEDDFEMFYEVWEKFDPDATQFIEFCKLSDFAAALDPPLLIAKPNKVQLIAMDLPMVSGDRIHCLDILFAFTKRVLGESGEMDALRIQMEERFMASNPSKVSYEPITTTLKRKQEEVSAIVIQRAYRRYLLKQKVKKVSSIYKKDKGKEDEGTPIKEDIITDKLNENSTPEKTDVTPSTTSPPSYDSVTKPEKEKFEKDKSEKEDKGKDIRESKK
What is the function of this protein?
Mediates the voltage-dependent sodium ion permeability of excitable membranes.  Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient (PubMed:10827969, PubMed:11166117, PubMed:28137877).  Implicated in the regulation of hippocampal replay occurring within sharp wave ripples (SPW-R) important for memory (PubMed:29867081).
What are the official names of this protein?
Sodium channel protein type 2 subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.2.
What is the protein family that this protein belongs to?
Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.2/SCN2A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.