PharMolix/UniProtQA huggingface dataset:
Protein: ISL3_ONCTS
Sequence: MVDIIFNSSFLGDMGDHSKKKSGFAMCVGCGSQIHDQYILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCAKCNLGFSSSDLVMRARDNVYHIECFRCSVCSRQLLPGDEFSLRDEELLCRADHSLLMERTSAGSPISPGHIHSNRSLHLAAEPVTVRAPHRNHVHKQSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMREQLVEMTGLSPRVIRVWFQNKRCKDKKRSILMKQLQQQQHSDKTVSIFSLQGLTGTPLVARSPIRHDNTVQGNSVEVQTYQPPWKALSEFALQSDLDQPAFQQLVPFSESGSLGNSSGSDVTSLSSHLPDTPNSMVPSPVET
What is the function of this protein?
Binds to one of the cis-acting domain of the insulin gene enhancer.  May be involved in subtype specialization of primary motoneurons.
What are the official names of this protein?
Insulin gene enhancer protein ISL-3, Islet-3.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS7_BURVG
Sequence: MRVAEVVRNTSETQIRVKLDLDGTGRQKLATGVPFLDHMLDQIARHGLIDLEVEAHGDTHIDDHHTVEDVGITLGQAVAKAVGDKKGIRRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPFTRARIGTFDVDLSIEFFRGFVNHAGVTLHIDNLRGINAHHQLETVFKAFGRALRAAVELDERAAGQIPSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_CAMC5
Sequence: MLMPKRTKFRKQMKGRNRGYATRGASLSTGEFALKAVEAGRVNSRQIEAARQALTRHVKRQAKIWIRVFPDKPLTKKPLQTRMGKGKAGVEEWVMNIKPGRILFEMAGVSEELAREALTLAMHKLPFKSKFVTRESENEIY
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DUT_SCHPO
Sequence: MSFFVQKLSEKATIPTKGSANSAGYDLYAAAECIVPRRGKVLVDTDLAIAVPEGTYGRVAPRSGLASKHSIDTGAGVIDADYRGHVRVLLFNYSDVDFPIKVGDRIAQLILERIVNPPVILVESLEATVRGANGFGSTGV
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Probable deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: ATPG_AROAE
Sequence: MASGKEIRTKIKSVQNTRKITKAMEMVAASKMRKAQDRMRAARPYAEKIRRLAANLSQANVTDYKHAFLVQKDEVKRVGLILVTTDKGLCGGLNTNIQRVALNAMKGWDASGTTEIQACCIGNKGFGFMQRMGAKVVSHVVQLGDTPHLEKMIGPVKIMLDAFQNGELDAVYVAYTRFINTMKQEPVLEQLLPLTGEKLGTPEGSWDYLYEPDPQVVIDEMLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKNVIGELQLVYNKTRQAAITKELSEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HMP_DEIRA
Sequence: MLTPEQKAIVKATVPALEAHGETITRTFYASMFAAHPELLNIFNPANQQTGKQARSLAASVLAYAAHIDHPEALGGMVGRIAHKHVSLEVLPEHYPIVGQYLLGAIAGVLGDAAKPEILDAWAAAYGELADLMIGIEKGMYDAGAGQPGGWRDFRPFRVARKVAESRVITSFVLEPVGGGALPAYQPGQYLSLKVKVPGQERWQIRQYSLSDAPSPDHYRISVKREGGGLVSEYLHGAVQEGDELLVHVPAGDFVLQQSERPVVLISAGVGITPMLAMVQTLAQAGSQRPVTFIHAAQNGSVHAFRDDVARLTHEYPHFRKVVFYDEAGPDDQLGTHHDVAGRLSLDAVRGALPAGEAEFYYCGPAGFAGAVEAILDDLQVPAERRFTETFGPSQSFAPVILG
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: GL24_ARATH
Sequence: MDSRCFGFFFTLLSLNVIVLAYDPDTLQDLCVADRTSGIKVNGFTCKPESNITASDFFFAGIGKPAVVNNTVGSAVTGANVEKIAGLNTLGVSLARIDYAPGGLNPPHTHPRATEVIFVLEGELDVGFITTANKLFAKTVKKGEVFVFPRGLIHYQKNNDKAKPASVISAFNSQLPGTQSIAATLFTATPAIPDHVLTTTFQIGTKEIEKIKSKFAPKKV
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 2 member 4.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: TRPC_DECAR
Sequence: MSDILNKIIATKREEVAAARLAKPLAIVEAEAIAQPAPRDFVGAIRNKIANDRPAVIAEIKKASPSKGIIRPDFQPADIARSYEQHGAACLSVLTDRQYFQGCPEYLQSARAACALPVLRKDFMVDAYQVAEARAMGADAILLIAAALTLEEMQALETQASAYGMAVLVEVHNGEELDAALQLKTPLLGINNRNLRTFAVTLETTLGLLSRIPAGRIVVTESGILKPEEVALMRTNKVNAFLVGEAFMRVPEPGAELARLFA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: GPDA_RUEST
Sequence: MSVAVLGAGAFGTALAISLARKAPTTLWCRSKDHADEIRSTRENTRRLPGAPLPDALAVTSDIACLGAHDVILLAVPMQKMRGFLTAHHAALSGKTLVACCKGIELDSGLGPVAVLRDTVPDATAALLTGPSFAADIALGLPTALTLACDPDETGKALQATLSTDNLRLYRTTDLTGAEIGGALKNVIAIACGAVIGARLGDSARAALMTRGYAEMQRLALARGARPETLAGLSGFGDLTLTCGSELSRNFRLGLSLGRGEAFDPSITVEGAATARATAKTAQEMGLEMPITQTVTNLLDQRLTISDAADQLLKRPLKEE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_BIFA0
Sequence: MLRWQTAGESHGEALVAMIEGMPSGVRVTSQDIRDALARRRLGYGRGARMKFEQDQVRLLTGVRFGSTLGSPIAIEIGNTEWPKWTEVMSADPLDHELAREGRNAPLSRPRPGHADLTGMRKYGFDDARPVLERSSARETASRVALGEVAALFLEQVAGIRTVSHVISIGGAGVESDNTPLPGPDDVAALDASPVRTLDKDAEERMVARIDEAKAKADTLGGVIEVIAYGVPAGIGTYVESDRRLDAALAAAVMGIQAIKGVEIGDGFLEAGRPGSMAHDEMVPGDDGCIARLSNRAGGIEGGMSNGQPIRVRAAMKPIPSIPRALRTVDITTGEAAQAINQRSDSTAVPAAAVVAEAMVRLTLAQHLLEKFGGDSIEETRRNIEGYLASWPEHMR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: KN7G_ARATH
Sequence: MGIGEDQMQGSSGREEKIFVSVRLRPLNVRERARNDVADWECINDETVIYRSHLSISERSMYPTAYTFDRVFGPECSTREVYDQGAKEVALSVVSGVHASVFAYGQTSSGKTYTMIGITDYALADIYDYIEKHNEREFILKFSAMEIYNESVRDLLSTDISPLRVLDDPEKGTVVEKLTEETLRDWNHFKELLSICIAQRQIGETALNEVSSRSHQILRLTVESTAREYLAKDKFSTLTATVNFIDLAGSERASQSLSAGTRLKEGGHINRSLLTLGTVIRKLSKGKNGHIPFRDSKLTRILQTSLGGNARTSIICTLSPARVHVEQSRNTLLFASCAKEVTTNAQVNVVMSDKALVRHLQRELAKLESELSSPRQALVVSDTTALLKEKDLQIEKLNKEVFQLAQELERAYSRIEDLQQIIGEAPQQEILSTDSEQTNTNVVLGRQYPKLRVRSSWESLNITPESPLSAQASIMISPQSTEHGSDENVFQLSDLRLNSGASSPAQHLAFVTPGKFTKVRLNIRGVESKNQLHIHKGESVDQSRVQGERLHEMDEPSEVDSEDTCTELQCIETESPGIIMYPEPNILPDRCKAVSALPLCEPESKNSRPPTETAEEKEEKEETEEKEEEEEERVKEVSSVSIQTKEKSGPIKVSPRCVLSLTDESFPDESSNLKRDPTHQDFVTPSPEKLYAWHLESNGQTAGGTGFTRSRSCGASFVSSSSFSLSERDANTPPCWYQNERAESNLKPSNSKRPPLPKHISRMSMPATWFEKDFNHTQRMPAGLDGVNMIKSSPNGSQVSTSKSHVYARQTSGRALISQDEGEETVPQRDKRIIHLSMEEIEQKFLALRSSKSFKDAAVDPIQDYLTMPLNWPLEFKRLEMEIIELWHACNVSLSHRSYFFLLFRGDQKDCLYMEVELRRLKYIRETFTHNNKAIENGRTLTSMSSLRALNRERYKLSQLMQKKLTKEERENVFLRWGIGLNTKHRRLQLAHRLWSESKDMDHVRESASVVGKLMGFVDMDLASKEMFGLNFSLRPRAKKSSLWKRSVLSLSIL
What are the official names of this protein?
Kinesin-like protein KIN-7G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-7 subfamily.
Protein: RL11_PORG3
Sequence: MAKEVAGQIKLQIKGGAANPSPPVGPALGAKGINIMEFCKQFNARTQDKAGKVLPVVITYYADKSFDFIVKTPPVAIQLLEASKQKSGSAEPNRKKVAEITWEQVRTIAEDKLVDLNCFDIKAAMKMVAGTARSMGIAIKGDFPE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PGK_BACAN
Sequence: MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGAKVILASHLGRPKGQAVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKNDAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAVSGLLMEKELEVLGKALSNPERPFTAIIGGAKVKDKIGLIRHLLDKVDNLIIGGGLAYTFVKALGHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTKIVGIDSIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQALADAEGTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALMA_HALRO
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin-A, CaM A.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: SEY1_LACBS
Sequence: MASAAPINLRAQDTPYVPPTSLPTSSSQTGSTARIQIIDDEKKFTPDLATQIERWGLRDAGFSYNIVAVFGSQSTGKSTLLNRLFGTTFDVMDETRRQQTTKGIWMCRGKDMGVMVMDVEGTDGRERGEDQDFERKSALFSLASSEILIVNLWEHQVGLYQGANMGLLKTVFEVNLGLFGKKAQDGSNGRTLLLFVIRDHIGQTPLANLQATLTADLNRIWESLSKPTDLKDRLLSDYFDLAFTALPHKILSADKFESEVQELRTRFVDKESSDYLFKPAYHKRIPADGVAFYMEGIWEQVQTNKDLDLPTQQELLAQFRCDEISAVALAEFNEQAKSQKRPVEGGRVVEGLGAMMNNWRTQALTRYDRDASRYHKGVYGRKRADLVAVLDSTLSPLFLGQLKNLHKSCLVTFKKEMLDGLHGEDYDFANVFKRAREKSERTFSEGGKEALVEGTDWSWEEELELLRDEIRAVADQCRKDETTKMINLIERNLKKHISEPVELHLGKASPDMWDEILRVFRDTLDKAEKTYLTKAKSFNCTEEENTAALDALRKRGWVALRAKIDEQTADPIILGKLRNHFEERFRYDEQGVPRVWKPDDDIDSAFMKAKDQTLDLVPLYSKISPKDTSLEFNLPSESNDSFSNDDFDLSTSPVIFTETKCLDLTNKFRRDADAYYVEAKRSTVASIAQIPYWIYGVLVVLGWNEAMLVLFNPLYFAFLLLAMATSYIIAQLGLVGPLFQVTRTVGSEIQRQATARLREHFSQPVLAEPVQVGPSRDREEVGQIQ
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: OBG_RALPJ
Sequence: MKFIDEARIEVIAGDGGNGSASMRREKFVPFGGPDGGDGGRGGSVWAVADRNINTLIDYRFAKKHLARNGENGRGADCYGAAGDDITLRMPVGTAIYDADTEELIADLTIDGQRLCLAQGGEGGWGNIHFKSSTNRAPRQKTDGKAGERRNLRLELKVLADVGLLGMPNAGKSTLITAISNARPKIADYPFTTLHPNLGVVRTGPSKSFVVADIPGLIEGAAEGAGLGHQFLRHLQRTRVLLHVVDLAPFDESVDPVAEAKAIVGELKKYDAELFDKPRWLVLNKLDMVPEDEREARVKDFVKRFKWKGPVHRISALTHDGTQALVHAIQEYLDELRAEEDAAAAAPDQRLDPTLHNVDHDDQA
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_PARMW
Sequence: MTSPAALSPTPFGRVVTAMVTPFDDSGAVDLPLAGRLARHLVEQGSDGLVVSGTTGESPTLSWQEQLQLLQAVREAVGSDAQVLAGTGSNCTAEAVEATRQAAAAGADGALVVVPYYNKPPQDGLAAHFRAIAEAAPELPLMLYNIPGRTGCSMAPETVAQLMDCPNVVSFKAASGTTEEVTALRLACSSKLAIYSGDDGLTLPMISVGAVGVVSVASHVVGPQIRAMIDAYMQGDAAVALALHEQLQPVFKALFATTNPIPVKAALQLNGWSVGDPRPPLSPLPDDMRSTLAQTMAALRQT
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SHEB9
Sequence: MELVLKDAQSALEVSETTFGRDFNEALVHQVVVAYAANARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKGPIWRGGGVTFAAKTQDHSQKVNKKMYRGALKSILSELVRQERLVVVESFGVEAPKTKELKAKLKAMNLEDVLIVTAEVDENLFLAARNLYKVDVRDVAGLDPVSLIAFNTVLVTADAVKQIEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS18_STRPS
Sequence: MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PRIC1_RAT
Sequence: MPLEMEPKMSKLAFGCQRSSTSDDDSGCALEEYAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEEEKKELQVFSAQRKKEALGRGTIKLLSRAMMHAVCEQCGLQMNGGEVAVFASRAGPGVCWRPSCFVCFTCNELLVDLIYFYQDGKIHCGRHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCCGCFESLYAEYCETCGEHIGVDHAQMTYDGQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSKTCSLGEDIHASDSSDSAFQSARSRDSRRSVRMGRSSRSADQCRQSLLLSPALNYKFPGLSGSADDTLSRKLDDVSLSGQGAGFAHEEFWKARVDQEASEDPEEWAEHEDYMTQLLLKFGDKNLFQQPPSEVDMRASEHWIPDNMVTNKPEAKQNHQSLASKKYQSDMYWAQSQDGLGDSAYGSHPGPASSRRLQELDLDHGAAGYNHDQTQWYEDSLECLSDLKPEQSVRDSMDSLALSNITGASVDGESKPRPSLYSLQNFEEIEAEDCEKMSNMGTLNSSMLHRSAESLKSLNSELCPEKIIPEEKPVHLPVLRRSKSQSRPQQVKFSDDVIDNGSYDIEIRQPPMSERTRRRVYHFEERGSRPHHHRHRRSRKSRSDNALNLVTERKYSAKDRLRLYTPDNYEKFIQSKGARELQAYMQNANLYGQYAHTTSDYALQNPGMTRFLGLYGDDDDSWCSSSTSSSDSEEEGYFLGQPIPQPRPQRFTYYTDDLSSPASALPTPQFNQRTTKSKKKKGHRGKNCIIS
What is the function of this protein?
Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure (By similarity).  Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis.  Necessary for nuclear localization of REST.  May serve as nuclear receptor (By similarity).
What are the official names of this protein?
Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Nucleus membrane. Cytoplasm, cytosol. Note=A smaller amount is detected in the cytosol.
Protein: VF229_IIV6
Sequence: MNKNSKNKMDLDTKELPSLSFSLRENSRVFLDYMYVYDNISVFPAKFVTQFPKFLNYLKYSKYDYSMLESNNRILFVAVNSNELITISTFDNCVFFGFAIVNILNQSLEVIMSEDNSRNIKIRLLDVVTHLFTNNLYVRLTIDNVNFDVDVVFLVEYGFGDPTLIDNSIVLLKYIKRILPETTLSIIQEIVGSIKTNLYTIKVFIPRVVAETLSKCVKYINEAAGVLSLVKYNENGVGILGLNSENITEGGLDAVNLPSQRAPFVFHSHPDKVTREYGAFISWPSGQDMRVVASQYLADMDQLAHFVIGPEGIWVIHLTPGFQTILQVLKESQNVDCGNAILEAVYQTFTKFDYDRDISTDPIERYKASDRYLSAVKHYRVSNLFSDVPVAKNICKPQLQEDVRLFDVNLLKWKLFDRGGVQLSFSYILDIRGGLSFFIFPYM
What are the official names of this protein?
Uncharacterized protein 229L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 229L family.
Protein: GANS_BACSU
Sequence: MKMAKKCSVFMLCAAVSLSLAACGPKESSSAKSSSKGSELVVWEDKEKSNGIKDAVAAFEKEHDVKVKVVEKPYAKQIEDLRMDGPAGTGPDVLTMPGDQIGTAVTEGLLKELHVKKDVQSLYTDASIQSQMVDQKLYGLPKAVETTVLFYNKDLITEKELPKTLEEWYDYSKKTADGSKFGFLALFDQIYYAESVMSGYGGYIFGKAKDGSYNPSDIGINNEGAVKGAALIQKFYKDGLFPAGIIGEQGINVLESLFTEGKAAAIISGPWNVEAFSNAGINYGITKLPKLENGKNMSSFIGVKSYNVSAFSKNEELAQELAVFLANEKNSKTRYEETKEVPAVKSLANDPAIMKSEAARAVTEQSRFSEPTPNIPEMNEIWTPADSALQTVATGKADPKQALDQAAETAKGQIKAKHSGK
What is the function of this protein?
Involved in galactan degradation (PubMed:27501980, PubMed:29240795).  Part of the ABC transporter complex GanPQS involved in the uptake of galactooligosaccharides (PubMed:27501980, PubMed:29240795).  Binds mainly galactotetraose and galactotriose (PubMed:27501980).
What are the official names of this protein?
Galactooligosaccharide-binding protein, Cyclodextrin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CH60_CHLTR
Sequence: MVAKNIKYNEEARKKIQKGVKTLAEAVKVTLGPKGRHVVIDKSFGSPQVTKDGVTVAKEVELADKHENMGAQMVKEVASKTADKAGDGTTTATVLAEAIYTEGLRNVTAGANPMDLKRGIDKAVKVVVDQIRKISKPVQHHKEIAQVATISANNDAEIGNLIAEAMEKVGKNGSITVEEAKGFETVLDIVEGMNFNRGYLSSYFATNPETQECVLEDALVLIYDKKISGIKDFLPVLQQVAESGRPLLIIAEDIEGEALATLVVNRIRGGFRVCAVKAPGFGDRRKAMLEDIAILTGGQLISEELGMKLENANLAMLGKAKKVIVSKEDTTIVEGMGEKEALEARCESIKKQIEDSSSDYDKEKLQERLAKLSGGVAVIRVGAATEIEMKEKKDRVDDAQHATIAAVEEGILPGGGTALIRCIPTLEAFLPMLTNEDEQIGARIVLKALSAPLKQIAANAGKEGAIIFQQVMSRSANEGYDALRDAYTDMLEAGILDPAKVTRSALESAASVAGLLLTTEALIAEIPEEKPAAAPAMPGAGMDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STPG4_MOUSE
Sequence: MAEPTVVIAPTTVPREDLGHGEPLLMTAKQVKKTPGLEREGWWRLTITDTPIPGTYHFRTFTEEALLNPVKITYNFKNEGRKKLPLVLRNDPVPTDLPQYSPPDFLELLKKQTASYSFKDKPRADPSTLVDKDESLHLCPGQYEVLPAPVPKSPARSFVFRSSVQRFPPNYFTPHEGPGPGDYELKASPKGSITSCFRSKVPRFLPVSSKTPGPGAYTSSRQFPKQSSTIAKMGREHSLFFNNTIGF
What is the function of this protein?
Maternal factor that plays a role in epigenetic chromatin reprogramming during early development of the zygote (PubMed:23560077, PubMed:28930672).  Involved in the regulation of gametic DNA demethylation by inducing the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) (PubMed:23560077, PubMed:28930672).
What are the official names of this protein?
Protein STPG4, Gonad-specific expression gene protein, GSE, Sperm-tail PG-rich repeat-containing protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in female and male zygote pronucleus (PubMed:23560077, PubMed:16571911). Associates preferentially with the paternal chromatin during zygote development (PubMed:23560077).
Protein: SYH_PORPU
Sequence: MAKIQAIRGTKDILPDEQLYWQFIHEKVASLLKYANYKEIKTPIFENSDLYDRGIGENTDIVNKEMYRFNDRSNRDITLRPEGTAGVVRAFIENRMDVQNRLQKLWYSGPMFRYERPQSGRQRQFHQLGIEFIGSSDARADAEIIHLAMNIFNDLSVNDLQLDINSIGKAEDRNHYQAKLQEYLEQYYDDLDTDSQNRLSSNPIRILDTKNKYTQTILNDSPRISDFLSLESEKHFDDVCDYLTLLNVPYKINTQLVRGLDYYNDTAFEIKILKSQGQDTLCGGGRYDSLIHQLGGNKTPAVGCAIGLERLLLVAKDNILLPHMSIDCYIVSKGIKARKIGIIITQFLRNQLVKTELDISSSNFGKQLKQAHKKRAIACLILGDNEIQQETITIKWMYTQEQENMSIIEFKNKISYLKKKIAFNKKFNSY
What are the official names of this protein?
Histidine--tRNA ligase, chloroplastic, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PA24A_BOVIN
Sequence: MSFIDPYQHIIVEHHYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISSTPDSRKRTRHFNNDINPVWNETFEFILDPNQENILEITLMDANYVMDETLGTTTFPISSMKVGEKKQVPFIFNQVTEMILEMSLEVCSSPDLRFSMALCDQEKAFRQQRKENIKENMKKLLGPKNSEGLHSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSHPDFPEKGPEEINKELMKNVSHNPLLLLTPQKIKRYVESLWRKKSSGQPVTFTDIFGMLIGETLIHNRMNTTLSSLKEKVNTGQCPLPLFTCLHVKPDVSELMFADWVEFSPFEIGMAKYGTFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSKGSTMEEELENITAKHIVSNDSSDSDDESQGPKGTEHEEAEREYQNDNQASWVQRMLMALVSDSALFNTREGRAGKVHNFMLGLNLNTSYPMSPLRDFTMQESLDEDELDAAVADPDEFEQIYEPLDVKSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVPRETNEEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKNAIVESIEYRRQNPSRCSVSLSSVEARRFFNKEFLSKPTA
What is the function of this protein?
Has primarily calcium-dependent phospholipase and lysophospholipase activities, with a major role in membrane lipid remodeling and biosynthesis of lipid mediators of the inflammatory response (By similarity).  Plays an important role in embryo implantation and parturition through its ability to trigger prostanoid production (By similarity).  Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity).  Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis via the cyclooxygenase pathway.  In an alternative pathway of eicosanoid biosynthesis, hydrolyzes sn-2 fatty acyl chain of eicosanoid lysophopholipids to release free bioactive eicosanoids.  Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 position of phospholipids (phospholipase A1 activity) only if an ether linkage rather than an ester linkage is present at the sn-2 position.  This hydrolysis is not stereospecific.  Has calcium-independent phospholipase A2 and lysophospholipase activities in the presence of phosphoinositides.  Has O-acyltransferase activity.  Catalyzes the transfer of fatty acyl chains from phospholipids to a primary hydroxyl group of glycerol (sn-1 or sn-3), potentially contributing to monoacylglycerol synthesis (By similarity).
What are the official names of this protein?
Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane. Nucleus envelope. Note=Translocates to intracellular membranes in a calcium-dependent way.