PharMolix/UniProtQA huggingface dataset:
Protein: MOBA_BACCQ
Sequence: MSKWAGIVLAGGMSSRFGEPKALASWQGSTFIEHILKLMTSALQEVVVISHSHIKERVEQLVQVPVIEDIPHYKGNGPLAGIVSGMEYIEADWYAIMPCDAPNVSHEWFTILLEQTSNNYDAVVPIINGRKQPLLAAYHNRVKEKIYALLQEEKRSMGQLLSQCNVKYIAGEDIQANADWFINVNTKEEYVQAQKDLSNE
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTU1_YEAST
Sequence: MKLKVTGAGINQVVTLKQDATLNDLIEHINVDVKTMRFGYPPQRINLQGEDASLGQTQLDELGINSGEKITIESSDSNESFSLPPPQPKPKRVLKSTEMSIGGSGENVLSVHPVLDDNSCLFHAIAYGIFKQDSVRDLREMVSKEVLNNPVKFNDAILDKPNKDYAQWILKMESWGGAIEIGIISDALAVAIYVVDIDAVKIEKFNEDKFDNYILILFNGIHYDSLTMNEFKTVFNKNQPESDDVLTAALQLASNLKQTGYSFNTHKAQIKCNTCQMTFVGEREVARHAESTGHVDFGQNR
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.  Participates in the regulation of the ubiquitin conjugation pathway involving CDC48 by hindering multiubiquitination of substrates at the CDC48 chaperone.  May be indirectly involved in PIS1 gene expression.
What are the official names of this protein?
Ubiquitin thioesterase OTU1, OTU domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISPG_TROW8
Sequence: MSIDLGLPKVREVLSPRRKTRRIKLGKVFVGGDSPILVQSMTTTQTTNIDATLQQIAELTAAGCDIVRVAVPSRDDAQVLHIIAKKSQIPVIADIHFQPNYVYAAIDAGCAAVRVNPGNIRKFDDQIGKIAEKAKAAGVSIRIGVNAGSLDPRLLEKYGRPTAQALVDSAVWEAGLFEEYDFHDFKISVKHHDPVTMVKAYRLLAERGDWPLHLGVTEAGPAFQGTIKSSTAFAVLLAEGIGDTIRVSLSAPPVEEVKVGLEILRSLGLRERRLEIVSCPSCGRAQVDVYRLAEEVTKGLEKLTVPLRVAVMGCIVNGPGEAREADLGVASGNGKGQIFVRGQVIKTVPESEIVPTLLEEANRLAGEMPFSSGSPTIAIV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RMUC_CHLPN
Sequence: MNLPVSLACLLLSGCVFFLGVFVSSSLYARKKRAFLEKIQKLEHENQLLQTSLNLSRHQEQLIEDFSNRLALSSHKLIKDMKEEAQNYFGDTSKSFQSILSPIQTTLTTFKQSLETFETKHAEDRGRLKEQISQLLAVEKKLEHETHVLTDILKHPGSRGRWGEIQLERILELAGMLKYCDYDSQTTSAQGAFRADIIIRLPQDRCLIIDAKAPISDSYFSVEEIDKGDLVDKIKEHIKTLKSKSYWEKFHQSPEYVILFLPGESLFNDAIRLAPELMEIGASSNVILSSPLTLLALLKTIAYMWKQENLQKQIQEVSLLGKELHRRLQVVFTHFQKIGKNLNQTVQSYNDMTSSFQYRVLPTLRKFEGLETSSSHQIEEPTPIESLATSFPHTCDIDTNLAVIESLEKQD
What is the function of this protein?
Involved in DNA recombination.
What are the official names of this protein?
DNA recombination protein RmuC homolog.
What is the protein family that this protein belongs to?
Belongs to the RmuC family.
Protein: ZBT24_MOUSE
Sequence: MADTTPEPCGQLMVHSDTHSDTVLASLEDQRKKGFLCDITLIVENVHFRAHKALLAASSEYFSMMFAEEGEIGQSIYMLEGMVADTFGILLEFIYTGYLHASEKTTEQILATAQFLKVYDLVKAYADFQDNHSAPKPPALNCTGTPVVVISNKKNDPLKRKRGRPRKANGLQEGRSELAAEGELQLRVNNSVQNRQNFVFKEEDSVKLSEQTPEDKESEPAGEPGSVEEVPAEKDENFDPKAGDGQESQSRCSRRRIRRSVKLKDYKLLGDEDDQSTAKRLCGRKKRSSGPEARCKDCDRVFKYSHFLAIHQRRHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCGKALTTKHSLLEHMSLHSGQKSFTCDQCGKYFSQKRQLKSHYRVHTGHSLPECSHCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCSICGKCFSDSSAKRRHCILHTGKKPFSCPECGLQFARLDNLKAHLKIHSKEKHTADSSSVSGSNVDEGRNILQLQPYQLSTSGEQEIQLLVTDSVHNINFMPGPSQGVSIVAAESPQSMATDPAANITLLTQQPEQLQGLILSAQQEQAEHIQSLSVIGGQMESSQTEPVHVITLSKETLEHLHAHQEQTTSSVPAADTGARATPVPSTRPGAELTQAPLAVPLDPSPGATVAGWPFGPSSYRSLKM
What is the function of this protein?
May be involved in BMP2-induced transcription.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 24, Bone morphogenetic protein-induced factor 1, Brain-specific protein 1, Zinc finger protein 450.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COPD_PSEUB
Sequence: MEDPLSIAVRFALYTDLMMLFGLALFGLYSLRGAERRSGAVLPFRPLLSATALIGLLLSVVSIVLMAKAMSGASEWLEAVPHAEMMVTQTELGTAWLIRMAALVGAAVTIAFNLRVPMASLLMVSLLGGVALATLAWTGHGAMDEGSRRFWHFSADILHLWSSGGWFGALVAFALMLRPNKVETLQSVQVLSRTLSGFERAGAVIVAFIVLSGVVNYLFIVGPQVSGVVESTYGVLLLGKLALFGLMVGLASANRFVLSPAFERAVHRGEYARAARSIRYSMALELGAAVLVLGLIAWLGTLSPEMEAGM
What is the function of this protein?
Exact function not known.  Involved in copper resistance.  Appears to be involved in copper uptake in conjunction with CopC.
What are the official names of this protein?
Copper resistance protein D.
What is the protein family that this protein belongs to?
Belongs to the CopD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CEL7A_MYCTT
Sequence: MGQKTLQGLVAAAALAASVANAQQPGTFTPEVHPTLPTWKCTTSGGCVQQDTSVVLDWNYRWFHTEDGSKSCITSSGVDRTLCPDEATCAKNCFVEGVNYTSSGVETSGSSLTLRQFFKGSDGAINSVSPRVYLLGGDGNYVVLKLLGQELSFDVDVSSLPCGENAALYLSEMDATGGRNEYNTGGAEYGSGYCDAQCPVQNWNNGTLNTGRVGSCCNEMDILEANSKAEAFTPHPCIGNSCDKSGCGFNAYARGYHNYWAPGGTLDTSRPFTMITRFVTDDGTTSGKLARIERVYVQDGKKVPSAAPGGDVITADGCTSAQPYGGLSGMGDALGRGMVLALSIWNDASGYMNWLDAGSNGPCSDTEGNPSNILANHPDAHVVLSNIRWGDIGSTVDTGDGDNNGGGPNPSSTTTATATTTSSGPAEPTQTHYGQCGGKGWTGPTRCETPYTCKYQNDWYSQCL
What is the function of this protein?
Endoglucanase that is involved in the biological conversion of cellulose to glucose.  Hydrolyzes internal beta-1,4-glucosidic bonds.  Shows relatively high activity toward barley beta-glucan and carboxymethyl cellulose (CMC), and lower activity toward lichenan, wheat arabinoxylan and other xylans.
What are the official names of this protein?
Endoglucanase 7a, Cellulase 7a, Endo-1,4-beta-glucanase 7a.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROB_ACET2
Sequence: MIKLNVNLQDRSYPIYISTDYSQIGKCIQSAKLTGKMVLITDTNVDKYQAEECVKAFSDAGYEVSKFVIPAGEENKNLDTTRDIYKYLLGLKLDRSATLMALGGGVVGDITGFAAATFLRGINFVQIPTTLLAQSDSSVGGKVGVDFEGTKNIIGAFYQPKFVYINVNTLKTLPERELKAGLAEVVKHGVIMDEEFYEYIDYNVHKILNHDEAVLQYIAKRNCSIKASVVEKDEKEGGLRAILNFGHTIGHAIETVMNFELLHGECVSLGMVGAMRMALYLEMIDEQSVNRVKNTLDKIGLPTRLEGIDVDKVYNQMFYDKKIKGSKLTFVLPRKRIGEVIQCTIDDEDLIKRVIASLGE
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSN_ALIFM
Sequence: MNSAVEQQLAELGIEAYLKEHQYKSLLRFLTCGSVDDGKSTLIGRLLHDSKQIYADQLDAVHADSQRVGTTGERPDLALLVDGLQAEREQGITIDVAYRYFSTQKRKFIIADTPGHEQYTRNMATGASTCNVAVILIDARKGVLDQTRRHSYIANLLGIRHFIVAVNKMDLVEYSQSRFEEIKEEYLAFSKKLNNPNLDISILPLSALEGDNVVNPSEALSWYQGEPLLEVLENVDIDADKGNGEFRFPVQYVNRPNLDFRGFAGTVSSGGISVGDEIVALPSGKKSKVARIVTFDGDLTSAQAGQAVTLTLEDEIDISRGDLLVKSQSNLQATDQFKAEIVWMTEKGLEPGRQYDIKIAGKKTVGQIDAIHHQVNINSLEKFDTQELPLNGIGLCDVSLTETVSLDRYQDCADTGGFIFIDRLTNVTVGAGMIQNLSDLSETKPINDNISAFEIELNALIRKHFPHWETQDISKLLG
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: PRL_MESAU
Sequence: MNSQGSDRKAVTLLLLVMSNLLFCQNAHPLPICPGGNCQMPLQELFDRVIMLSHYIYMLSADMFIELDKQYAQDHEFIAKAISDCPTSSLATPEGKEEAQQVPPEVLLNLILSLVHSWNDPLFQLVTEVDGIHEASDAIISRAKEIGEQNKRLLEGIEKILGQAYPEAKGNEIYSVWSQFPSLQGVDEESRDLAIYNKVRCLRRDSHKVDNYLKLLRCRVVHNNNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPC1_ARATH
Sequence: MAMATRVLAQSTPPSLACYQRNVPSRGSGRSRRSVKMMCSQLQVSGLRMQGFMGLRGNNALDTLGKSRQDFHSKVRQAMNVPKGKASRFTVKAMFERFTEKAIKVIMLAQEEARRLGHNFVGTEQILLGLIGEGTGIAAKVLKSMGINLKDARVEVEKIIGRGSGFVAVEIPFTPRAKRVLELSLEEARQLGHNYIGSEHLLLGLLREGEGVAARVLENLGADPSNIRTQVIRMVGENNEVTANVGGGSSSNKMPTLEEYGTNLTKLAEEGKLDPVVGRQPQIERVVQILGRRTKNNPCLIGEPGVGKTAIAEGLAQRIASGDVPETIEGKKVITLDMGLLVAGTKYRGEFEERLKKLMEEIRQSDEIILFIDEVHTLIGAGAAEGAIDAANILKPALARGELQCIGATTLDEYRKHIEKDPALERRFQPVKVPEPTVDETIQILKGLRERYEIHHKLRYTDESLVAAAQLSYQYISDRFLPDKAIDLIDEAGSRVRLRHAQVPEEARELEKELRQITKEKNEAVRGQDFEKAGTLRDREIELRAEVSAIQAKGKEMSKAESETGEEGPMVTESDIQHIVSSWTGIPVEKVSTDESDRLLKMEETLHKRIIGQDEAVKAISRAIRRARVGLKNPNRPIASFIFSGPTGVGKSELAKALAAYYFGSEEAMIRLDMSEFMERHTVSKLIGSPPGYVGYTEGGQLTEAVRRRPYTVVLFDEIEKAHPDVFNMMLQILEDGRLTDSKGRTVDFKNTLLIMTSNVGSSVIEKGGRRIGFDLDYDEKDSSYNRIKSLVTEELKQYFRPEFLNRLDEMIVFRQLTKLEVKEIADILLKEVFERLKKKEIELQVTERFKERVVDEGYNPSYGARPLRRAIMRLLEDSMAEKMLAREIKEGDSVIVDVDAEGNVTVLNGGSGTPTTSLEEQEDSLPVA
What is the function of this protein?
Molecular chaperone that hydrolyzes ATP and is associated with the chloroplast protein import apparatus.  May function as the motor for chloroplast protein translocation, as translocation requires ATP hydrolysis in the stroma.  May interact with a ClpP-like protease involved in degradation of denatured proteins in the chloroplast.  Involved in the regulation of chlorophyll b biosynthesis through the destabilization of chlorophyllide a oxygenase (CAO) protein in response to the accumulation of chlorophyll b.  Involved in leaf iron homeostasis.
What are the official names of this protein?
Chaperone protein ClpC1, chloroplastic, ATP-dependent Clp protease ATP-binding subunit ClpC homolog 1, Casein lytic proteinase C1, Protein DE-REGULATED CAO ACCUMULATION 1, Protein IRON-RESCUED MUTANT 1.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chloroplast membrane. Note=The membrane association is important for the in vivo functions.
Protein: ACP_PROMT
Sequence: MSQEAILEKVRSIVAEQLSVEAGEVKPDSNFQNDLGADSLDTVELVMALEEAFDIEIPDEAAEGIATVGDAVKYIEEKQS
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LTV1_HUMAN
Sequence: MPHRKKKPFIEKKKAVSFHLVHRSQRDPLAADESAPQRVLLPTQKIDNEERRAEQRKYGVFFDDDYDYLQHLKEPSGPSELIPSSTFSAHNRREEKEETLVIPSTGIKLPSSVFASEFEEDVGLLNKAAPVSGPRLDFDPDIVAALDDDFDFDDPDNLLEDDFILQANKATGEEEGMDIQKSENEDDSEWEDVDDEKGDSNDDYDSAGLLSDEDCMSVPGKTHRAIADHLFWSEETKSRFTEYSMTSSVMRRNEQLTLHDERFEKFYEQYDDDEIGALDNAELEGSIQVDSNRLQEVLNDYYKEKAENCVKLNTLEPLEDQDLPMNELDESEEEEMITVVLEEAKEKWDCESICSTYSNLYNHPQLIKYQPKPKQIRISSKTGIPLNVLPKKGLTAKQTERIQMINGSDLPKVSTQPRSKNESKEDKRARKQAIKEERKERRVEKKANKLAFKLEKRRQEKELLNLKKNVEGLKL
What are the official names of this protein?
Protein LTV1 homolog.
What is the protein family that this protein belongs to?
Belongs to the LTV1 family.
Protein: LIPA_DECAR
Sequence: MAEKGVKQKGELKTARIPIKIVPVDTPLRKPEWIRVKAGNSAGRFGEIKSMLREKKLHTVCEEAACPNIGECFGRGTATFMILGDICTRRCPFCDVGHGQPLPPNPNEPAELADSVSSLKLQYVVITSVDRDDLRDGGAQHFVDVVRAVREASPKTTIETLVPDFRGRMDIAIDILGNGLPDVLNHNMETVPRLYKQARPGADYAHSLALMKQFKARYPDVKTKSGLMVGLGETDEEILEVMRDLRANDVEMLTIGQYLAPSGHHLPVSRYVHPDTFKMFEEEAKKMGFSGAACAPMVRSSYWADQQAHSAGVA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ALCBS
Sequence: MQVSVETTSGLERRVTVGVPAEKVDVAVEGKLQEAQKTIRLDGFRPGKVPMREVKRRFGGAVRNEVLADVMREAFIEAVEQEKLQPAGMPGFEATTNEAGKDLEFVATFEVYPQVELAAFDSIEVEKPQSEVTDADVDTMIETLRQQRAEFADVDRASEIGDRVNIDFKGLKDGEAFEGGTAEGQNLELGSGQMIPGFEDGIVGMKAGEEKDIDVTFPEDYQSEDLKGQAVVFHIKVNKVEGKALPEVDAEFMKGFGVDDGDETKFKAEVRKNMERELKNAITSKVKEQAMDGLVNLHEFDLPGALVTQEIQRMRQQMMQQFGGGQQFDPSILPDDLFKEQAERSVRLGLVVRAILDKNEIKADADKVKARVEEISEQYEKPEEVVSWVYSNPQQLQQIEGAILEEQVVDLVLESAKVEEKTMPYQDAVKPREQADG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: UBP42_MOUSE
Sequence: MTIVDKTEPSDPSTCQNQPGSCEAVSPEDMDTGSASWGAVSSISDVSSHTLPLGPVPGAVVYSNSSVPEKSKPSPPKDQVLGDGIAPPQKVLFPSEKICLKWQQSHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQTHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVTKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTISLKRFANFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIIYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRAVLNQQAYVLFYIRSHDVKNGGESAHPAHSPGQSSPRPGVSQRVVNNKQVAPGFIGPQLPSHVMKNTPHLNGTTPVKDTPSSSVSSPNGNTSVNRASPATASTSVQNWSVTRPSVIPDHPKKQKITISIHNKLPARQGQAPLNNSLHGPCLEAPSKAAPSSTITNPSAIQSTSNVPTTSTSPSEACPKPMVNGKAKVGASVLVPYGAESSEESDEESKGLAKENGVDMMAGTHSDRPEAAADDGAEASSHELQEPVLLNGANSADSDSQENSLAFDSASCQVQPELHTENLFSKLNGLPGKVTPAPLQSVPEDRILETFKLTNQAKGPAGEESWTTTGGSSPKDPVSQLEPISDEPSPLEIPEAVTNGSTQTPSTTSPLEPTISCTKEDSSVVVSAEPVEGLPSVPALCNSTGTILGDTPVPELCDPGDLTANPSQPTEAVKGDTAEKAQDSAMAEVVERLSPAPSVLTGDGCEQKLLLYLSAEGSEETEDSSRSSAVSADTMPPKPDRTTTSSCEGAAEQAAGDRGDGGHVGPKAQEPSPAKEKMSSLRKVDRGHYRSRRERSSSGEHVRDSRPRPEDHHHKKRHCYSRERPKQDRHPTNSYCNGGQHLGHGDRASPERRSLSRYSHHHSRIRSGLEQDWSRYHHLENEHAWVRERFYQDKLRWDKCRYYHDRYTPLYTARDAREWRPLHGREHDRLVQSGRPYKDSYWGRKGWELQSRGKERPHFNSPREAPSLAVPLERHLQEKAALSVQDSSHSLPERFHEHKSVKSRKRRYETLENNDGRLEKKVHKSLEKDTLEEPRVKKHKKSKKKKKSKDKHRDRESRHQQESDFSGAYSDADLHRHRKKKKKKKRHSRKSEDFIKDVEMRLPKLSSYEAGGHFRRTEGSFLLADGLPVEDSGPFREKTKHLRMESRPDRCRLSEYGQGD
What is the function of this protein?
Deubiquitinating enzyme which may play an important role during spermatogenesis.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 42, Deubiquitinating enzyme 42, Ubiquitin thioesterase 42, Ubiquitin-specific-processing protease 42.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: TRPF_GEOUR
Sequence: MTKVKICGITTVEDALMAIEAGADALGFVFYDKSPRNIIPERAAEIIGSLPPFIHVVGLFVHAHLDFVNATADRCRLDIVQLHGDESREFCSRVNRRVIKAFRVKDITSLDRMEEYRVAGYLLDAYSPKAFGGTGITFNWDTAVVAKKFGPIILAGGLTPDNVTEAIGHVSPYGVDVSSGVESAPGVKDPAKVREFIKRAKGL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: HIS4_YEAST
Sequence: MTKFIGCIDLHNGEVKQIVGGTLTSKKEDVPKTNFVSQHPSSYYAKLYKDRDVQGCHVIKLGPNNDDAAREALQESPQFLQVGGGINDTNCLEWLKWASKVIVTSWLFTKEGHFQLKRLERLTELCGKDRIVVDLSCRKTQDGRWIVAMNKWQTLTDLELNADTFRELRKYTNEFLIHAADVEGLCGGIDELLVSKLFEWTKDYDDLKIVYAGGAKSVDDLKLVDELSHGKVDLTFGSSLDIFGGNLVKFEDCCRWNEKQG
What is the function of this protein?
Catalyzes the isomerization of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR.
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 5-proFAR isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_BURCJ
Sequence: MARTQAEPPASQPDARAAWLRDQLERANYAYYVLDQPDLPDAEYDRLFRELQQLETDHPELVTPDSPTQRVGGEAAGGFTPVVHDAPMLSLNNGFADEDIVAFDKRVADALAKATDLAGSVTDPVEYACELKFDGLAISLRYENGVFVQAATRGDGTTGEDVTENVRTIRSIPLKLKGKHVPAVLDVRGEVLMFKRDFARLNERQRAAEQREFANPRNAAAGSLRQLDSKITAQRPLSFFAYGIGVLDGMPMPDTHTALLDWYEAFGLPVNRERAVVHGAEGLLDFFRKVGEKRESLPYDIDGVVYKVNRRDEQERLGFVSRAPRFALAHKFPAQEALTKLVAIDVQVGRTGAITPVARLEPVFVGGATVTNATLHNEDEVRRKDIRIGDTVIVRRAGDVIPEVVGALLDRRPADAAEFVMPTECPVCGSKIERLPDEAIARCTGGLFCPAQRKQALWHFAQRRALDIDGLGEKIIDQLVELNLVRTPADLFNLGFATLAELDRFAEKSAQNLLDSLEKAKHTTLARFIYGLGIRHVGESTAKDLAKHFGSLTPIMDASIEELLEVNDVGPIVAESIHQFFAEEHNRTVIEQLRAPGKVTWPEGPPAPKAPQGVLAGKTVVLTGTLPNLTRDAAKEMLEAAGAKVAGSVSKKTDYVVAGAEAGSKLAKAEELGIPVLDEDGLHQLLEGNTP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RCO3_NEUCR
Sequence: MAIFAMGWQKPDNVAGSSAPAIMVGLFVATGGLLLGYDTGTINGILAMKSFKDHFSTGYIDGNGQPGIYPKESALIVAMLSAGTAIGALLAAPLGDHYGRRRSLIGAIGIFVIGAILQVCAYNIDLLVAGRTVAGVGIGIVSVLVPLYQSEMAPKWIRGTLVCTYQLSITMGLLAAAVVNILTYKLKTAAAYRVPIGLQLTWACVLALGLTVLPETPRYLIKRGDKNAAALSLSRLRRLDITHPALVEELAEIEANHQYEMALGPDSYKDILFGEPHLGRRTFTGCCLQMLQQLTGVNFIMYYGTTFFNNAGVGNPFKISLIMQVINTASTIPGLFVVESWGRRRLLMVGAIGMAICQLLIAAFATASGSNNLSAQNKVLITFVAIYIFFFAASWGPVVWVVTSEIYPLKVRAKSMSITTASNWFLNFGIAYGTPYMQTNSAASDESSIDLGSKVFFVWGAFCIVAVGFVWCMVYETSKISLEQIDEMYERVDHAWHSRRFEPSWSFQEMRDLGFSDGGIPPTQQLQQQPQQPQQQQQQHHQQQQHQLQVDLQQSQSRTSNSSTSQTDTGGSNNTGASQDDKLVASLGNIDLSY
What is the function of this protein?
Probable glucose transporter.  Involved in sugar transport, carbon catabolite repression, and initiation of conidiophore development.
What are the official names of this protein?
Probable glucose transporter rco-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CB042_HUMAN
Sequence: MEPNSLRTKVPAFLSDLGKATLRGIRKCPRCGTYNGTRGLSCKNKTCGTIFRYGARKQPSVEAVKIITGSDLQVYSVRQRDRGPDYRCFVELGVSETTIQTVDGTIITQLSSGRCYVPSCLKAATQGVVENQCQHIKLAVNCQAEATPLTLKSSVLNAMQASPETKQTIWQLATEPTGPLVQRITKNILVVKCKASQKHSLGYLHTSFVQKVSGKSLPERRFFCSCQTLKSHKSNASKDETAQRCIHFFACICAFASDETLAQEFSDFLNFDSSGLKEIIVPQLGCHSESTVSACESTASKSKKRRKDEVSGAQMNSSLLPQDAVSSNLRKSGLKKPVVASSLKRQACGQLLDEAQVTLSFQDWLASVTERIHQTMHYQFDGKPEPLVFHIPQSFFDALQQRISIGSAKKRLPNSTTAFVRKDALPLGTFSKYTWHITNILQVKQILDTPEMPLEITRSFIQNRDGTYELFKCPKVEVESIAETYGRIEKQPVLRPLELKTFLKVGNTSPDQKEPTPFIIEWIPDILPQSKIGELRIKFEYGHHRNGHVAEYQDQRPPLDQPLELAPLTTITFP
What are the official names of this protein?
Uncharacterized protein C2orf42.
Protein: PURL_LEPBL
Sequence: MEKDVVSLQDALEHGLTAEEFQKIQEILGRIPNSTELGIFSAMWSEHCSYKNSVLKLKTLPTSSDKLLAKAGEENAGAMDIGDGLAVVFKIESHNHPTAVEPYQGAATGVGGIMRDIFTMGARPIVSLNSLRFGNPDEPRNKYLLSRAVKGIGDYGNSLGIAVSGGELFIDECFSKNPLVNAMTVGIVRHDQMASATTGGQVGNAVYIVGATTGRDGIHGASFASKDLSKESESKRSAVQVGDPFMEKLLMEASLEAIQKGLLIGIQDMGAAGISCATSEMSAKGKTGMKIDLDLVPFRETGMNAYEVMLSESQERMLVVPKKGKESELVSIFEKWNLNAVRIGEVTADGFIEIYMGGKLKAHIPAESLVLGGGAPRYERETKRPSYLDAVKTWKPNSILDITPGANTKDVLLNILSSWNVCSRKPITEQYDSEVGLVKLIGPGLDGGLSSIPDTNKALATATDCNSRYTYLDPYKGAQFAVCEAARNVYVTGATPYGVTNNLNFANPYIPENYYMFSECIRGMGDACRFLGLPVTGGNVSFYNESPEGPIFPTPTIGMVGILQDKKKFLSNFPKEVGIELAVLGNFRPSLGGSEYLKKIHGQVNGSIPEIDIKEELELCKLILSLNEKGALKSARDLSLGGIGIALSKTILFSGLGIDAELIAFKQSRLDLTLFGESSTTVLVGFDSSWKEKIREQTEEKGLKFYPVGKTTSSELLKLKDIGVEVSFSELNGPYEKGLEVVFAL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEFB1_BOVIN
Sequence: DFASCHTNGGICLPNRCPGHMIQIGICFRPRVKCCRSW
What is the function of this protein?
Has bactericidal activity.  Active against E. coli ML35 but not against S. aureus 502A (PubMed:8454635).  May act as a ligand for C-C chemokine receptor CCR6.  Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner.  Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (By similarity).
What are the official names of this protein?
Beta-defensin 1, BNBD-1, BNDB-1.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.