PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_MARSD
Sequence: MAKLDKIRNFSIIAHIDHGKSTLADRILEITGMVSEREKKDQYLDKMELEQERGITIKAQTVRIPYKANDGEEYILNLIDTPGHVDFSYEVSRSLAASEGALLVVDSTQGVEAQTLANVFLALDHDLEIVPVLNKVDLPSSDCERVAQEIEEVIGLDCSEPLMISAKTGLNVEDVLESIVKDLPAPQGDPDAPLKALIFDSWYDSYQGVVVLFRILDGTIKKGDKIQIHSTGRTFDVTTLGVYTPEPQKAKELAAGEVGFLCASMKELNDAPVGDTITLAADPVEDPFPGFQEVKPMVFCGLYPVEPAEYEPLKAALEKLQLNDTAFSFEPETSTALGFGFRCGFLGLLHMEIIQERLEREFQAKLIATAPSVVYQARLNNGEVLEIDNPSKMPDGGDLESLAEPFCRLEIHVPNDYVGAVLKLCEEKRGIQKDMRYLTSSRVIITYEVPFAEIMYDFFDKLKSHTKGYASLDYEIIDYRESNLVKLDILINTDPVDAFSAIVHKDSAYPFGRSLALKLKRAIPRQMFEIVIQAAIGRKIIAKERVAPFRKNVTAKCYGGDITRKRKLLEKQKEGKKRMKKMGNVEIPQEAFMAVLKAGED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YG58_SCHPO
Sequence: MLYVSNLPVGTSSSAIHALFSAYGNVKDIWMLSPDNSAIVSYESLSSAIVARDALHNRPVFENHGPVQVMLAKPSSNYEPGNITAAVSPPASTSSKDGVVCSPTSTGASQLLKSRVDILEVARQFEMRINLDIVDSMIASAIENNKVATEILPPVETLRSRQFEASKLREIRKNIDSGFYTQEEIEVIARSMLDDVAELSSDYLGNTVVQKFFEYCSDPIKEAMLERIAPYLAAIGIHKNGTWAAQKIIDVASTEKQMDLIVKHLRPYTALLYFDQFGNYVAQCCLRFKYPKNTFLFEVMARHCCEIGQSRFGARAIRACLENENATFEQQALVVASIIINSHLLATNSNGMLLLTWLLDNSFFRNRHRLLAIHLATHLHTTCTHKLASTLIFKLINNKQEPESRNLLLKNLFFSEKDNVLTYILQDQAVGPSFIHKVITYPSIGREFLAQFHLVIKRVLINIHAQPNAVYCRLMEEVGMTSKSISPSLSGISAPSASVDSSASRLARDFGSLSLSSNSLLGSLGGLESTPAYPSYPSHIPLGTASLPLKGNLYQISRSDDIKSGAPVLDTSSLVNPTLAKSASLNNSSLLNPSSSLLRREVPAGKLTMPAYPYTTQLMNHTAGADYGLPRLSSKLPQVFPGNYPRLQQSLFPRQGELRFN
What are the official names of this protein?
Pumilio domain-containing protein C56F2.08c.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTL_ECO45
Sequence: MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSALFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWTMATMGIALLMLSLFILKETRPAAPTTSDKPRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA
What is the function of this protein?
Confers resistance to chloramphenicol.
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EASC_ASPFU
Sequence: MLIERGLLSIMASKCSGTWSTYKTYTTANGCPFMKPEGPPADGRTLALNDHHLVESLAHFNREKIPERAVHAKGAAAYGEFEVTADISDICNIDMLLGVGKKTPCVTRFSTTGLERGSAEGMRDLKGMATKFYTKEGNWDWVCLNFPFFFIRDPLKFPSLMHAQRRDPRTNLLNPNMYWDWVTSNHESLHMVLLQFSDFGTMFNWRSLSGYMGHAYKWVMPNGSFKYVHIFLSSDRGPNFSQGEQAKDNSDLDPDHATRDLYEAIERGDYPTWTANVQVVDPAEAPDLGFNILDVTKHWNLGTYPKDLPKIPSRPFGKLTLNRIPDNFFAEVEQLAFSPSNMVPGVLPSEDPILQARMFAYPDAQRYRLGPNHHKIPVNQCPMTFNPTLRDGTGTFDANYGSLPGYVSESQGVNFARPQEHDPKFNAWLSQLSSRPWMQTNENDYKFPRDFYNALPEFRSQEFQDKMVENIIASVAQTRREIREKVYHTFHLVDPELSARVKRGVEKMDASFKQVSLSRL
What is the function of this protein?
Catalase; part of the gene cluster that mediates the biosynthesis of fumiclavanine C, a fungal ergot alkaloid (PubMed:15933009, PubMed:23435153, PubMed:26972831).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:15870460).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by EasD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:20039019, PubMed:20526482, PubMed:21409592, PubMed:23435153).  EasA reduces chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:20526482).  EasG then catalyzes the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:20526482).  Hydrolysis of festuclavine by easM then leads to the formation of fumigaclavine B which is in turn acetylated by easN to fumigaclavine A (PubMed:26972831).  Finally, easL catalyzes the conversion of fumigaclavine A into fumigaclavine C by attaching a dimethylallyl moiety to C-2 of the indole nucleus (PubMed:19672909).
What are the official names of this protein?
Catalase easC, Ergot alkaloid synthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: KDSA_SHESA
Sequence: MSNKIINLGSIEIANDKPFVLFGGMNVLESRDLAMSIAETYAEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLKIFEEIKKTFNLPLITDVHETYQCAPVAEVVDIIQLPAFLARQTDLVVAMAKTGAIINVKKPQFLAPHEMRHIITKFNEAGNDEIILCERGSCFGYNNLVVDMLGMDEMKQSGYPVIFDATHALQRPGGRADSAGGRRAQATELARSGMALGLAGLFIEAHPDPDNAKCDGPCALPLHQLENYLKQMKAIDDLVKSFDPIDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_ORITI
Sequence: MTTFLNINQIRTTFIEFFKKYGHHHASSSSLVPGNDPSLFFVNAGIVQFKDYVRAPETSKYSRVVTCQKCVRAGGKHNDLESVGYTARHHTFFEMLGNFSFGEDNAKADFMQLIWNFLTKELFIDEDRLIVTVYHTDHETAKLWRSIAGLDDSRIIRIKTDDNFWSMGPVGPCGPCTEIFYDHGDKIPGGLPGTKDENGGRYVEIWNIVFMQYEQLNESTRVELAKRCIDTGAGLERIATVLQGVYDNYDIDLFKNLIANIEHLTKIKSVGEANFSHRIIADHLRASAFLIADGVMPSNDGRGYVLRRIMRRAMNQIHQLGCKEPVMHLLVQGLINEMGDFYKELRVRQELITYLLKNEEEKFKTTLSKGLKLLEEESKNLTSGSQLSGHIAFKLYDTYGFPFDLTQDILKKRSISINKTEFDQNMLEQQNRARQLWKGQGSNKEQLLWEKLKEEFRATEFVGYSLCQAEGIVVSLIQDNQYVEYIDINQVDDNNKEFWLITNQTPFYGQSGGQIGDIGIIKNNECTIHVTDTIKLFGCTHVHICKIVSGKINLNAVVHMAIDKQYRTQLQIHHSATHILHAALREILGNHIIQKGSLVAYDYLRFDVSHPTSISKDLLTKIENRVNEIILNNTAVKLRIMPFDQAIAHGAVALFEEKYGDEVRAISIGETSDARYYSFELCGGTHVKYTGDIGAFRILSESAIAAGVRRIEAIAGKHVIKQARQNSELLDLIAEKFSVTKQTIMSKIDGIIEENNLLKKQLHQLKYNQLILCEKDIQNMADNIGKIKLVYKNIEDYDLQIVRKAVSNTTKNIQNLVMVVISNNDKKSTIIIGVSDNITNKIQANNLVKEIINYIGGSGGGSATLAQIGCQYTSKLLDLKNIICKLLAT
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_MYCSK
Sequence: MNGTISVLLAGGGTAGHVEPAMAVADALAALEPGVRITALGTERGLETRLVPERGYALELITPVPLPRKLSGDLARLPMRVRRAVRETREILDTVHADVVIGFGGYVALPAYLAARRNRVPIVVHEANASAGLANKVGARFARRVLSAVADPGLGRVEVVGTPVRSSITELDRAALRAEARAHFGFADDARVLLVFGGSQGARSLNNVVSGAAKALAAAGISVLHAYGAKNTLELPDPAPGDPPYVAVPYLSRMDLAYAAADLAICRSGAMTVAEVTAVGLPAVYVPLPIGNGEQRLNARPVVETGGGLVVDDADLSPQFVADTVVPLLTDTGRLQTMTAGAALSGHRDAARHVAHVALDVAREAAGGRKGVR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SCP42_ARATH
Sequence: MASVSWRAVAVAMVVVLLSLQWFAKGYPEEDLVVRLPGQPTVGFKQYAGYVDVDVKAGRSLFYYYVEAVKQPDSKPLTLWLNGGPGCSSIGGGAFTELGPFYPTGDGRGLRVNSMSWNKASHLLFVESPAGVGWSYSNKSSDYNTGDKSTANDMLVFLLRWFEKFPKLKSRDLFLTGESYAGHYIPQLADAILSYNSHSSGFKFNIKGVAIGNPLLKLDRDSPATYEFFWSHGMISDELKLTITSQCDFDDYTFASPHNVSTACNEAISETENIITEYVNNYDVLLDVCYPSIVQQELRLKKMATKMSMGVDVCMTYERRFYFNLPEVQKALHANRTHLPYSWSMCSGVLNYSDIDGNIDMLPILKRIILNKTPIWIFSGDQDSVVPFGGSRTLVRELAQDLNFKTTVPYGAWFHKSQVGGWAIEYGKLLTFATVRGAAHMVPYAQPSRALHLFSSFVSGRRLPNNTHSSTDE
What is the function of this protein?
Probable carboxypeptidase.
What are the official names of this protein?
Serine carboxypeptidase-like 42.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_BUCAP
Sequence: MDIAILNTGCANLTSIQVAIKKLGYDSIVTSDPSIVLKSKKIFLPGVGTALAAMEQLHKKNLINTLKKLTQPILGICLGMQIFSQFSEECKGVKTIGIFDNCFTHLLKSSNLPLPHMGWNHIVFNNLHPLFKNIDKKERFYFVHSYIIPLNKYTLAKTKYGVSFSSVMQKNNFFGVQFHPEKSGDAGAQLLKNFLEI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDC4_DANRE
Sequence: MASSSSMDIEGATQHLRDILKLDRPGNSAEASLVESQRKPSFNGELNGVLGSDLMGAAMVEPTVHNSDKLNGQDTQTICLSGDDGSICVPIRANIVEIVSSRDSSIDSKARGSNKVKIQPVAKYDWEHKYYYGNLIAVSNTYLAYAIRGANNHSMIRVLHLSSTERSLLKGFTGAVTDLAFAHLDSTLLGCVDEAGNMFIWQLTSHSSKIQDEVIVHIRRPEDTPLNSNRRLIWCPFIPEDNDESPEDACQTLALLHEDRAEVWDLDILRSNNSSWPVDATELKEGFITIRGHAARISEGALSPDGTVLATASHDGYVKFWQIYIEGQDQPRCLHEWQPHNGQPLSCLLFCDNHKKQDPDVPFWRFLITGADQNQELKMWCTVSWTCLQTIRFSPDPFNCGVLPSLKASLDLSAEFLILSDVQRKVLYVMELLQDQEKGRASFTAVSEFLLTHPVLSFGVQDVSRARLRHTEVLPPEEESESMTAEGNQGTSESRSGIQIKLYCVHTKSLQDVQIWFQPNQGDSSSLFMPQSGSQDGFSFSDPLADLNVEAMSSDKESGDSGSQNDLSKILPLPSPADFMSPAPSALPKLMTPDAFMTPSASMPASPGSSASSLTIVTAMSSSDSGARGGDDLTQSPKMSVECVNSSFANAGSPRSNSILISGLGENIQVSPPNPPLSLDLQAIDPMVVPQASPTRARSPDVISSASTAMSQDIPEIASETLQRGLSGANADSGPILHSDSMASAASILHLLSPRARSSAEHSLLPLELGAASVDGEQRLSNTPSLLETALSQENAGAAGGSCSDSSVNHAWPAAPDITRETRNSLRDNGLGDCSREEIKDRHISSPYHRRTYHLTQNDSQDASAEQSDHDDEVASLASSSGNCGPRSSHRLPVKDWKTSPRSSPKLKRKSKKDEGESSQSRQIESQMSTEVQDELLQMLRSQQREIAELRQNQLDLLQRVTSHMDAVQSSMMAHIEHAMLAQQEQEQRRMERILVEGQSRNQQLQDQLVQQLVQTLNNSLCNRLEKVLREEMKKTVPQTISKSLEPVTGQMNSTIAAKLTAVEGALKENVTKVVKSKNTTDAIGRAAAEAMQGPIQAAYKETFQSIVLPVFERGCQSMFQQINDSFKQGTNEYIQQLETHIKNRKQRDQDTRDPVIGQLQQMIDSLQSSQDQLASTVTASVSSDVQHQLHMIVGNLQDSILTQVQRIVKGEVSLAMKEQQAAVTSSIMQAMRSAAGTPVPSAHLDYQAQQASILQLLQQGQLNEAFQQALSAADLNLVLYVCETIDSQQVFGQQPCPLHQAVLLSLIQQLSTNLSTRTELKISYLEDAVMNLDHGDPVTRDHMSAVLTQVRQKLFLFLQQDAHSPMSKRARRLMMMLQGLVNH
What is the function of this protein?
In the process of mRNA degradation, seems to play a role in mRNA decapping.
What are the official names of this protein?
Enhancer of mRNA-decapping protein 4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EDC4 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Nucleus.
Protein: FGD1_MOUSE
Sequence: MHGHRVPGGPGPSDPERSAANTPGAAPLACADSDPGALEPGLPVSRGSGTALGGPLDPQFVGPSDASLGAPPSSRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQSLEPHPEGPQRLRSDPGPPTEIPGPRPSPLKRAPGPKPQVPPKPSYLQMPRVLPPPEPIPPPPSRPLPADPRVAKGLVPRAEASTSSAAVSSLIEKFEREPVIVASDRPAPGPCPVPPEPAMLPQPPPQPTGSQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDDGPPIHSLCPGPPALASMPVALADPHRPGSQEVDSDLEEEEEEEEEEKEREIPVPPMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNMPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNRDDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLIYDNNRSNRVCTDCYVALHGAPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFEVGPPEAGERPDRRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDKEMEETPVAASGATAEPPEASQTRDKT
What is the function of this protein?
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP.  Plays a role in regulating the actin cytoskeleton and cell shape.
What are the official names of this protein?
FYVE, RhoGEF and PH domain-containing protein 1, Faciogenital dysplasia 1 protein homolog, Rho/Rac guanine nucleotide exchange factor FGD1, Rho/Rac GEF, Zinc finger FYVE domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Note=Associated with membrane ruffles and lamellipodia.
Protein: MOBP_RAT
Sequence: MSQKVAKEGPRLSKNQKFSEHFSIHCCPPFTFLNSKREIVDRKYSICKSGCFYQKKEEDWICCACQKTSRRATSPQKPKHQPAASPVVVRAPPAKPKSPPRPAKPRSPPIPAKPRSPSRTERQPRPRPEVRPPPAKQKPPQKSKQPARSSPLRGPGTSRGGSPTRAPRFW
What is the function of this protein?
May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
What are the official names of this protein?
Myelin-associated oligodendrocyte basic protein.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Present in the major dense line of CNS myelin. Isoform 5 may be differentially localized in the oligodendrocytes or perinuclear region. Isoform 2, 4, 5 and 6 are highly enriched in myelin. Isoform 1 and 3 are not enriched in mylein.
Protein: URE1_BURMS
Sequence: MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDTDTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALAGDGARNDNFRAKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIVKGGMIAVAQMGDPNASIPTPQPVHYREMFATRGGALARTSLTFVSQLALDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_SHELP
Sequence: MIFIPPFEQGKLLRRYKRFLADVLLDDGTEITIHCPNTGSMRNCLFPGERVWFSTSDNPKRKYAHTWEQAASDEGHIIGINTGRANALAAEAIEAGVISELTGYDRLRREVKYGSENSRIDLLLESEDKPACYIEVKSCTLLEQGQGYFPDAVTTRGQKHLRELMEMVKQGHRAVLLFVVQHTGITTVAAARHIDPEYAELLTQAHQAGVEILAYSCELSPSAAKLIKSCPVKL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: Y371_CAMJE
Sequence: MKKIKKIIQIGMIGGLAAVAGGALAGCGSNNDNADTLNQAANAQGAFVIIEETAPGQYKIKDQYPSDETRVVLKDLNGTERILSKEEMDALIKEEAAKIDNGTSNLTKDNGQISSGGLSLGETLLASAAGAILGSWIGSKLFNNQNFANQQRGAFSNQSAYQRSVNSFNKAGTTSSASSAKKSGFFGGGSKATSSSSSFGS
What are the official names of this protein?
UPF0323 lipoprotein Cj0371.
What is the protein family that this protein belongs to?
Belongs to the UPF0323 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ACCD_BACVZ
Sequence: MLKDIFTKKKKYASVPSEQAKHDVPEGIMTKCPKCKKIMLTKELDKNLRVCMNCGHHFPMNAKQRIESLLDEDSFEEFNQGMISENPLGFPEYLEKIEKDREKTSLNEAVVTGKGTISGFPAVIAIMDSTFRMGSMGSVVGEKITLAIEKAKEEKVPFIIFTASGGARMQEGVLSLMQMAKTSSALKLFSEEQGLIISVMTHPTTGGVSASFASLGDYNFAEPGTLIGFAGRRIIEQTIGEKLPEDFQTAEFLLKHGQLDAVIHRNDMKDKLAFLLDMHQTGGEYEWLQD
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_HELPS
Sequence: MKYTELKDKSIKELEELLHAKKAELFELHVKLKAMQLSNPNEIKKARRNIARINTAINAYYSSSVE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PNCA_ECOLI
Sequence: MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG
What is the function of this protein?
Is also able to hydrolyze the first-line antituberculous drug pyrazinamide (PZA) into pyrazinoic acid in vitro, but this reaction is not considered to be physiologically relevant.
What are the official names of this protein?
Nicotinamidase, Nicotinamide deamidase, NAMase, Pyrazinamidase, PZAase.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family.
Protein: THIE_CALS4
Sequence: MKRIDFTLYAITDRSFIKGMDIAEAVEIAIKNGVTVVQLREKDISSREFYEIALKVKEVTRKYNVPLIINDRVDIALAVDAEGVHVGPDDLPVGVVRRILGPDKIVGGSAYSVEEALKAEKEGADYIGAGSVFAQPVKPEAEVIGIEGVRKIKEAVNIPVVAIGGVNKTNAYEVILHSGVDGISAIAGIFDGDIEANTKDMLREIRRAFKERGK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RNC_BRUC2
Sequence: MNRTRPLPEIKMVSANKTASILEERTGHRFLNLKRLERALTHSSVQAPARANYERLEFLGDRVLGLTVAEMLFEAFPEASEGELSVRLNALVNAETCAAIADEIGLADLIHTGSDIKSLNDKRLLNVRADVVEALIATIYLDGGLEAARSFIQRYWKKRSLETGAARRDAKTELQEWAHQQGNVHPVYAILSRSGPDHDPLFLVEVTVKGFAPEKGEGRSKRIAEQSAAEAMLYREGVWKRDGSA
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1L_HALSA
Sequence: MDVSDVTSRYNDRLRVTDYADAATNGLQVGPGDRSVERIAFAVDAAAATISDAVEWGADLLVVHHGVAWGGLDAVTGREYDRIAALVDGECALYAAHLPLDGHPELGNAAHVADVLGLTQRSPFGDHSGEQIGLQGQLPDPTSAPALSKSLAAALPTGDQPVQVLDVGPAELTDVAVVTGSGADWLREAEANGVDALVTGEGKGKLYHEAREAGVSVFLAGHYATETGGVRALEAVADDWGVETRFISHPTGL
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: HIS5_BLOPB
Sequence: MNIVIIDTNCSNLLSVKTMLHRLGHNPIISDRADVISQADKLFLPGVGTASSAMKQLKKKNLITLIQNCTKPILGICLGMQLFGSISSENNGVNTLNIIHTPVKRMQYHGFPLPHMGWNTITIPKKHFLFYGIKENDYFYFAHSYCIKVCSVTISQTNYGQLFSSVIKYKNFFGVQFHPEKSGMPGQQLVKNFLEI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEPH_MOUSE
Sequence: MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAALAAKIPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVASRVGSLKARLPSCSSTYSVSEVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQPTQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPGNPVSAVVTCNLFVVPALRKMQGILDPRPTIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL
What is the function of this protein?
Has also a catalytic activity and catalyzes two steps in the biosynthesis of the molybdenum cofactor.  In the first step, molybdopterin is adenylated.  Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
What are the official names of this protein?
Gephyrin.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MoeA family.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Lipid-anchor; Cytoplasmic side. Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell projection, dendrite. Postsynaptic density. Note=Cytoplasmic face of glycinergic postsynaptic membranes (By similarity). Forms clusters at synapses (PubMed:25025157).
Protein: RL17_MAGSA
Sequence: MRHGMSGRKLNRDKSARKALFVSLANALLKHEQIKTTLPKAKDARPIVEKLITLGKRGDLHARRQAYAFLRDDKVVAKLFAVIGPRYKERQGGYCRVLKAGFRYGDCAPMAIIELVDRDLAAKGTDSGPTADKKADADEE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: Y940_STRM5
Sequence: MPVTPTSLADHLLVALPSLLDATFARSVALICQHDENGAMGVLVNQPSEYTLGEVLAQMDITTGDGDLQARMVLNGGPVHPERGFVIHDDARAWDSSLIVGEGLYLTTSRDILEAMARGEGPANAVVTLGCAGWGAGQLESELSENSWLTVPADAELVFQLPLEQRWQGAASRIGVDLFRLTDYSGHV
What are the official names of this protein?
UPF0301 protein Smal_0940.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.