PharMolix/UniProtQA huggingface dataset:
Protein: SYP_LEPCP
Sequence: MKASQFFIATLKEAPADAEVKSHQLMMRAGMIKRLGAGIYNYMPMGLRVIRKVEAIIREEMNRAGAVELLMPVVQPAELWQETGRFDKMGPELLRVKDRHDRDFIIQPTSEEVVTDIARQELRSYKQLPKNFYHIQTKFRDERRPRFGIMRGREFTMKDAYSFDRDAASAARSYDAMFAAYKRIFDRFGLQYRAVAADTGAIGGDLSHEFQVIADTGEDAIVYCPTSDYAANIELAEAVSLIAERGAATESMAKTPTPGKSTCADVAQLLNLPLARTVKSLVLATDELNEAGDVAKTTVWLLLVRGDHDMNEVKVGKVDGLKAGFRFATVAEIESHFGCKPGYLGPIGLKKPVKVIADRTVAQMADFICGANEIDFHLTGINWGRDLPEPDAVADIRNVVEGDPSPDGQGVLAIQRGIEVGHVFFLGTKYSKAMNATYLDENGKPQFMEMGCYGIGVTRILGAAIEQKHDARGILWPDAIAPFTVVVCPIGYDRSAEVKAAADALHDELQAAGIDVMLDDRGERPGAMFADWELIGVPHRVVISDRGLKAGQVEYQGRCDEAASTVPAAEVAAFVKGRLRS
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCS_PSEAE
Sequence: MPVNLSMTPINKAKAWGVHAVTASGVILALLALLALVDNKPQACLLWLGLALLVDGLDGTLARKYEVKEMLPHFDGSVLDLVIDYLTYVFIPAIFIYRYIPLPEHFELLAVGVILVSSLFCFCNVNMKSTDNYFVGFPAAWNVVAVYFYVLDLHPWVNLATVLVLAALTLTRMKFLHPFRVRQFMPLNIAVTFVWLISSGLLIVQQPADLPILLGLWFAASAYFVGICLWRSAREWFG
What is the function of this protein?
Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP.
What are the official names of this protein?
Phosphatidylcholine synthase, PC synthase, PCS, CDP-diglyceride-choline O-phosphatidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METN1_PARXL
Sequence: MIEIRNISQRFAGPRGSVEALHNVNLSIPAGEVFGIIGRSGAGKSTLVRTINLLTRPSEGNIVVNGRDLTTLPAAQLREARREIGMIFQHFNLLSSRTVYGNVALPLELAGMKRDEIEANVLPLLELVGLTAQKDRYPAQISGGQKQRVGIARALASKPKVLLSDEATSALDPETTRSILDLLRRINRELNLTIVLITHQMDVIKQVCDRVAVLDAGRVVEEGKVIDVFLQPHHEVTRALIGDVIAQELPPAMKARVAERLKTGSGHLLRLAFTGSGVDQPILSETIRRYELDFNILHGQIDEIQGQAFGSLAVLAGGEPAKVAQALTYLREQGVVVEELSYVE
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HCP_ECOLU
Sequence: MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YXT2_CAEEL
Sequence: MTNIVPRILGFVLFVLGAAIFLTEVMHSYHRFVKQSEEYSISNSNTDDAPTKKKQMKAFFSLYHNMDELKAQNSDVVQPRVLKGTAREFCNNTDHCIRPFLNHETRYRVAPDYKMAHCVVHKSMSTVITGIWCYLFNRNRFVRVDKQMNMSEWDKESLCRGDNTFRHLKSLQKKYNASEMTGWSLSMITRDPIDRFISGYVDRCIRVAEGPSPCNGCDKNMTCFILSEYERFKKQAHKGVLTNTFEDRHFYPQNWRCDIKTMRNKYEFIRYSSDASKELMEDLFKIARRQGIPEKELEYIENELTKNRKTSHTTAYSPAREFFQRRLRESPLLMEYVVRMFYHDFVILNYPLPEGF
What are the official names of this protein?
Uncharacterized protein C18B2.2.
What is the protein family that this protein belongs to?
To C.elegans C41C4.1 and C18B2.1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FMT_STRAW
Sequence: MKLVFAGTPEVAVPALDALIASGRHEVAAVVTRPDAPAGRGRRLVASPVAQRAEEAGIEVLKPVKPRDEEFLARLREIAPDCCPVVAYGALLPRVALDIPAHGWVNLHFSLLPAWRGAAPVQHSIMAGDEITGASTFLIEEGLDSGPVFGTVTEEIRPTDTSGDLLTRLAFAGSGLLVATMDGVEEGKLKAVPQPADGITLAPKITVENAHVDWSTPALRVDRVVRGCTPAPGAWTVFRGERLKLIQVVPVPERTDLAPGALSVGKNNVYVGTGSYAVELLWVQAQGKKPMRAADWARGVRITDGEPLGA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HIRA_ARATH
Sequence: MIAEKPFWVKHEGLQIFSIDVQPNGERFATGGGDHKVRIWNMKSVDKDLQNIDTKERLLATLRDHFGSVNCVRWAKNSRYVASGSDDQVIQIHERKPGSGTTEFGSGEAPDVENWKAVMTLRGHTADVVDLNWSPDDSMLASGSLDNTVHIWNMRTGMCTTVLRGHLSLVKGVTWDPIGSFIASQSDDKTVIIWRTSDWGMAHRTDGHWAKSLGSTFFRRLGWSPCGHFLTTTHGFQKPKHSAPVLERGEWSVAYDFLGHSAPIIVVRFNHSMFKRIPSSTHETKQVGWSNGTSKSGEKDLQSYNVIAMGSQDRTITVWTTGSARPLFVAKHFFGQSVVDLSWSPDGYSLFACSLDGTVAMIHFDPKELGVRLTDTELDELKKSRYGDVRGRQANLVESPAQLLLETASTKQAGSKRAASDVQQNQVTTKPSVSVESTAKRRKSQVDDRNKAAESTGQTLNKASTLNRVSSPVNQKVYRRPDGRKRIIPEAVGVPQQENNIMINGESHNFLPASAAAPAKGDSGDFPVEISNRDLSGKEIVCRNPDLKERSRITARATITESLVIEKVPGTSGRDGVLNVEQSVGIKESSSTDLLIRVFDWKDGEAAPPVCLEACPREHALDTVGAVSTSMVKETEISCKKSGETLWSDRIMGRVTVLAGNPNFWAAGCEDGSLQVYTKCGRRAMPTMMMGSAATFIDCDDSWKLLLVTRKGSLYVWDLFNRKCVLHDSLSSLVSSDVNLSSTVKGTIKVISVKLSKSGSPLVVLATRHAFLFDTSLMCWLRVADDCFPASNFSSSWNLGSAPCGELAGLQVDVRKYMARKPGWNRITDDGTQTRAHLESQLASSLALESPNEYRQCLLAYVRFLAREADESRLREVCESFLGPPTGMAEAASSDTNLSWDPYVLGVKKHKLLRNDILPAMASNRKVQRLLNEFIDLLSEYEDVETADPAPKGSTPTMNCGGVPSSLDQIGSDPPAMTATTPMTIDNDKPVSLENPAALDIGVCEKTGSEDRDKQDQNSRDSGS
What is the function of this protein?
Histone chaperone involved in maintining knox genes silencing throughout leaf development (PubMed:16243907).  Involved in heterochromatic and euchromatic gene silencing, especially upon salt stress (PubMed:25600486).  Involved in gene expression reprogramming during dedifferentiation probably by modifying histone H3. 3 recruitment at the nucleolus (PubMed:25086063, PubMed:25600486).  Contributes to maintenance of silencing of pericentromeric repeats and certain transposons (PubMed:25600486).
What are the official names of this protein?
Protein HIRA, Histone regulator protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Localized at rDNA loci in the nucleolus.
Protein: NSRR_ECO5E
Sequence: MQLTSFTDYGLRALIYMASLPEGLMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: PHLD_PSEF5
Sequence: MSTLCLPHVMFPQHKITQQQMVDHLENLHADHPRMALAKRMIANTEVNERHLVLPIDELAVHTGFTHRSIVYEREARQMSSAAARQAIENAGLQISDIRMVIVTSCTGFMMPSLTAHLINDLALPTSTVQLPIAQLGCVAGAAAINRANDFARLDARNHVLIVSLEFSSLCYQPDDTKLHAFISAALFGDAVSACVLRADDQAGGFKIKKTESYFLPKSEHYIKYDVKDTGFHFTLDKAVMNSIKDVAPVMERLNYESFEQNCAHNDFFIFHTGGRKILDELVMHLDLASNRVSQSRSSLSEAGNIASVVVFDVLKRQFDSNLNRGDIGLLAAFGPGFTAEMAVGEWTA
What is the function of this protein?
Type III polyketide synthase that catalyzes the synthesis of phloroglucinol from three molecules of malonyl-CoA (PubMed:15826166, PubMed:16931521).  In addition to its ability to produce phloroglucinol from malonyl-CoA, it exhibits broad substrate specificity, accepting C4-C12 aliphatic acyl-CoAs and phenylacetyl-CoA as the starters to form C6-polyoxoalkylated alpha-pyrones from sequential condensation with malonyl-CoA (PubMed:16931521).
What are the official names of this protein?
Phloroglucinol synthase, Type III polyketide synthase PhlD.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: NU5M_PHYIN
Sequence: MLLLTLIFLPFLGSVAAGLFGFYIGRKGSVFITTLTTFLSCIFSLIIIYNSITNEYEYIIYISNWINSGLFNCNWCFLFDSLTMIMLVVVTSISTLVHLYSSQYMAHDPHLSRFMSYLSLFTFFMIILVTGDNFMQMFVGWEGVGFCSYLLINFWFTRLQANKAAIKAMLVNRISDLILLLGVLTIFYNIRTIEYFSTFAAISIVKDFKFIFFNYILSIIDVACILIFIGAMGKSAQIFLHLWLPDAMEGPTPVSALIHAATMVTAGVYLTARCSPMFEYSMFSLKIITIIGASTAFFASTVGLVQNDFKKIVAYSTCSQLGYMFFACGLSNYPLAIFHLSNHAYFKALLFLCSGAVIHAMGDEQDIRKMGGLRRILPFTYIMFLIGSLSLMGFPFLTGFYSKDLILEVAFASFSETGHFAYWLGTIGAFFTAFYSTRLLFFAFLSETNAYKNIIKNAHDVPLEMGIPLGLLAFGSIFIGYISKDMFVGLGSDFWNNSIYINPFNNQMIDAEFLPTFFKLLPVILSFCGLFGAFYLYFFKFKFLYNLKISEYGLYFYNFLNRKWYFDKIYYEFINQYILKIGYNVTYKMIDKGLIEMCGPYGLTTIFSFLSQQIILLQTGYIYHYSLLMLISTIFLINIIFFSIIYYFNIITILLFLFIFLLIK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURC_CERS4
Sequence: MNAATKLPGELGPIHFVGIGGIGMSGIAEVLMTLGYRVQGSDAKASKITERLVSLGATFFEGQRAGNLGEAAVVVISSAIKKGNPELEEARLRGLPVVRRAEMLAELMRMRSNIAIAGTHGKTTTTTMVATLLDKGGFDPTVINGGVIHAYGSNARAGAGEWMVVEADESDGSFNRLPATIAIVTNIDPEHMEHWGSFDALRKGFYDFVTNIPFYGLAVCCTDHAEVQALVGRVTDRRIVTFGFNAQADVRAINLRYENGIAHFDVALQSEGTGHVIEGMSLPMPGDHNVSNALAAVAVARHLGMKKDEIREALAAFGGVNRRFTKVGEVGGVTIIDDYGHHPVEIAAVLKAARQAVKGRVIAVHQPHRYSRLHSLFDDFCTCFNEADVVAIAEVYAAGEDPIPGAGRDDLVAGLIAHGHRHARAILCEDDLERLVREQARPGDMVVCLGAGTISAWANNLPARLMGKAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMD1_BOVIN
Sequence: MAAELEGSKCLSGLLSGLAQDTFYGHPGITEELLRSQLYPEVSLEEFRPFLAKMKGILKSIASADMDFNQLEAFLTALTKKQGGITSEQAAVISKFWKSHKTKIRESLMNQSCWDRGLRSLSWRVDGKSQSRHSAQIHTPVAIMELEIGKSGQESEFLCLEFDEVKVNQVLKKLSEVEESISTLMQPA
What is the function of this protein?
Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins.  Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2.  Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation.  Down-regulates NF-kappa-B activity.  Involved in the regulation of membrane expression and ubiquitination of SLC12A2.  Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits and by promoting their ubiquitination presumably involving NEDD4L.  Promotes the localization of SCNN1D to recycling endosomes.  Promotes CFTR cell surface expression through regulation of its ubiquitination.  Down-regulates SOD1 activity by interfering with its homodimerization.  Plays a role in copper ion homeostasis.  Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes.  Can bind one copper ion per monomer.  May function to facilitate biliary copper excretion within hepatocytes.  Binds to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).  Involved in the regulation of HIF1A-mediated transcription; competes with ARNT/Hif-1-beta for binding to HIF1A resulting in decreased DNA binding and impaired transcriptional activation by HIF-1.  Negatively regulates neuroblastoma G1/S phase cell cycle progression and cell proliferation by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a FAM107A- and actin-dependent manner.
What are the official names of this protein?
COMM domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endosome membrane. Cytoplasmic vesicle. Early endosome. Recycling endosome. Note=Shuttles between nucleus and cytosol. Detected in perinuclear foci that may be aggresomes containing misfolded, ubiquitinated proteins (By similarity).
Protein: RPOE_STRMU
Sequence: MELEVFAGQEKSELSMIEVARAILEERGRDKEMYFSDLVNAIQVYLEKSDADIREALPFFYSDLNTDGSFIPLGENKWGLRSWYGIDEIDEEIVTLEEDEDGAPKHKRKRVNAFMDGDEDAIDYSDDDPEDESFNTAEEDTEYDEEDPDDEKSEVESYDSEINEIIPDEDLDENVDLDEEDDDYSDDEEDEEGE
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: PDRP2_STAEQ
Sequence: MKDNNEVLKLFIVSDSIGETAQRMIHATLTQFPDLTQVEIKKFPYIKDEQEFLNVLQLAKEQNAIVATTLVSESFNALGHQFANEHQIPYVDYMSELISIIKQHTHAKPLMESGALRKLNDEYFKRIEAIEYSVKYDDGKHFTDIGEADALIVGVSRTSKTPLSMYLANKGYKIANIPLVPEVAIPDNVFQQKNLKVFGLTASPNYIANIRRNRAETLGLSSESNYNSLERIKKELSYAEEVFRKLNATVINTEYKSIEESAFYIEKFLAKR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein 2, PPDK regulatory protein 2.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: HN_NDVI
Sequence: MDRAVGRVALENEEREAKNTWRFVFRIAIFLLIVITLAISAAALVYSMEASTPGDLVGIPTVISRAEEKITSALSSNQDVVDRIYKQVALESPLALLNTESVIMNAITSLSYQINGAANNSGCGAPVHDPDYIGGIGKELIVDDASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDISATHYCYTHNVILSGCRDHSHSHQYLALGVLRTSATGRVFFSTLRSINLDDNQNRKSCSVSATPLGCDMLCSKITETEEEDYSSVTPTSMVHGRLGFDGQYHEKDLDVITLFKDWVANYPGVGGGSFIDNRVWFPVYGGLKPNSPSDTAQEGRYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRVQQAILSIKVSTSLGEDPVLTVPPNTVTLMGPEGRVLTVGTSHFLYQRGSSYFSPALLYPMTVNNKTATLHSPYTFNAFTRPGSVPCQASARCPNSCVTGVYTDPYPLVFHRNHTLRGVFGTMLDDKQARLNPVSAVFDNISRSRITRVSSSSTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKEDGV
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: HISZ_BORA1
Sequence: MGNWLLPEGLADVLPAEARRIEELRRELLDLYRTYGFELVAPPLVEYIDSLLSGMGGDLNLYTCKLIDQLSGRTLGVRADMTTQVSRIDAHLLNRNSVTRLCYCGTVLHARPADLLSSRELLQIGAEIYGHVGFEADLEILQLVLETVAIAGVSRPRLDLSHPGVVKALFDADPAAAAISGRIIMLLREKDVAGLAELAGVEPALRADTLAALGALVRLYGEIDVIDRARQELPALPALVLALDELERLARAVPDVALGLDLADVGGYGYHSGVTFELYAQGWHDALVRGGRYDDVGRAFGRARPATGFSLDLRKLAAGLSPAEPGRAIRAPWGQDPALVGAVRALRHTGEIVVQVLPGHEHDQDEFVCDRELVLQDGAWTVKTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PO210_HUMAN
Sequence: MAARGRGLLLLTLSVLLAAGPSAAAAKLNIPKVLLPFTRATRVNFTLEASEGCYRWLSTRPEVASIEPLGLDEQQCSQKAVVQARLTQPARLTSIIFAEDITTGQVLRCDAIVDLIHDIQIVSTTRELYLEDSPLELKIQALDSEGNTFSTLAGLVFEWTIVKDSEADRFSDSHNALRILTFLESTYIPPSYISEMEKAAKQGDTILVSGMKTGSSKLKARIQEAVYKNVRPAEVRLLILENILLNPAYDVYLMVGTSIHYKVQKIRQGKITELSMPSDQYELQLQNSIPGPEGDPARPVAVLAQDTSMVTALQLGQSSLVLGHRSIRMQGASRLPNSTIYVVEPGYLGFTVHPGDRWVLETGRLYEITIEVFDKFSNKVYVSDNIRIETVLPAEFFEVLSSSQNGSYHRIRALKRGQTAIDAALTSVVDQDGGVHILQVPVWNQQEVEIHIPITLYPSILTFPWQPKTGAYQYTIRAHGGSGNFSWSSSSHLVATVTVKGVMTTGSDIGFSVIQAHDVQNPLHFGEMKVYVIEPHSMEFAPCQVEARVGQALELPLRISGLMPGGASEVVTLSDCSHFDLAVEVENQGVFQPLPGRLPPGSEHCSGIRVKAEAQGSTTLLVSYRHGHVHLSAKITIAAYLPLKAVDPSSVALVTLGSSKEMLFEGGPRPWILEPSKFFQNVTAEDTDSIGLALFAPHSSRNYQQHWILVTCQALGEQVIALSVGNKPSLTNPFPAVEPAVVKFVCAPPSRLTLAPVYTSPQLDMSCPLLQQNKQVVPVSSHRNPRLDLAAYDQEGRRFDNFSSLSIQWESTRPVLASIEPELPMQLVSQDDESGQKKLHGLQAILVHEASGTTAITATATGYQESHLSSARTKQPHDPLVPLSASIELILVEDVRVSPEEVTIYNHPGIQAELRIREGSGYFFLNTSTADVVKVAYQEARGVAMVHPLLPGSSTIMIHDLCLVFPAPAKAVVYVSDIQELYIRVVDKVEIGKTVKAYVRVLDLHKKPFLAKYFPFMDLKLRAASPIITLVALDEALDNYTITFLIRGVAIGQTSLTASVTNKAGQRINSAPQQIEVFPPFRLMPRKVTLLIGATMQVTSEGGPQPQSNILFSISNESVALVSAAGLVQGLAIGNGTVSGLVQAVDAETGKVVIISQDLVQVEVLLLRAVRIRAPIMRMRTGTQMPIYVTGITNHQNPFSFGNAVPGLTFHWSVTKRDVLDLRGRHHEASIRLPSQYNFAMNVLGRVKGRTGLRVVVKAVDPTSGQLYGLARELSDEIQVQVFEKLQLLNPEIEAEQILMSPNSYIKLQTNRDGAASLSYRVLDGPEKVPVVHVDEKGFLASGSMIGTSTIEVIAQEPFGANQTIIVAVKVSPVSYLRVSMSPVLHTQNKEALVAVPLGMTVTFTVHFHDNSGDVFHAHSSVLNFATNRDDFVQIGKGPTNNTCVVRTVSVGLTLLRVWDAEHPGLSDFMPLPVLQAISPELSGAMVVGDVLCLATVLTSLEGLSGTWSSSANSILHIDPKTGVAVARAVGSVTVYYEVAGHLRTYKEVVVSVPQRIMARHLHPIQTSFQEATASKVIVAVGDRSSNLRGECTPTQREVIQALHPETLISCQSQFKPAVFDFPSQDVFTVEPQFDTALGQYFCSITMHRLTDKQRKHLSMKKTALVVSASLSSSHFSTEQVGAEVPFSPGLFADQAEILLSNHYTSSEIRVFGAPEVLENLEVKSGSPAVLAFAKEKSFGWPSFITYTVGVLDPAAGSQGPLSTTLTFSSPVTNQAIAIPVTVAFVVDRRGPGPYGASLFQHFLDSYQVMFFTLFALLAGTAVMIIAYHTVCTPRDLAVPAALTPRASPGHSPHYFAASSPTSPNALPPARKASPPSGLWSPAYASH
What is the function of this protein?
Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity.
What are the official names of this protein?
Nuclear pore membrane glycoprotein 210, Nuclear pore protein gp210, Nuclear envelope pore membrane protein POM 210, POM210, Nucleoporin Nup210, Pore membrane protein of 210 kDa.
What is the protein family that this protein belongs to?
Belongs to the NUP210 family.
Protein: TXA1A_ETHRU
Sequence: MSRFCLLFVAFGFVLYFLHMEVTGKRTREDILKEAEQKGPEIKAMILENVQKCKTNCALHLKYEKCNELVPECCPKETPKCKSV
What are the official names of this protein?
U-scoloptoxin(10)-Er1a, U-SLPTX(10)-Er1a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CH60_KLEOX
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIIAEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKTLSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLEDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLVIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVTQIRKQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVDDALHATRAAVEEGVVAGGGVALVRVAAKLAGLTAQNEDQNVGIKVALRAMEAPLRQIVSNAGEEPSVVANNVKAGEGNYGYNAATEEYGNMIDFGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGG
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NGN3_HUMAN
Sequence: MTPQPSGAPTVQVTRETERSFPRASEDEVTCPTSAPPSPTRTRGNCAEAEEGGCRGAPRKLRARRGGRSRPKSELALSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALTQTLRIADHSLYALEPPAPHCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEERPGLLGATFSACLSPGSLAFSDFL
What is the function of this protein?
Acts as a transcriptional regulator.  Together with NKX2-2, initiates transcriptional activation of NEUROD1.  Involved in neurogenesis.  Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity).
What are the official names of this protein?
Neurogenin-3, NGN-3, Class A basic helix-loop-helix protein 7, bHLHa7, Protein atonal homolog 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2292_ROSCS
Sequence: MNPRQLEQMARQMQKEMMRIQEELANATVEGTAGSYITVTMNGHREIKSIKIAPEVVDPDDIETLQDLIVAAITDASKKAQELAEQRLGPLAGGMKLPGF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Rcas_2292.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LGT_HELPY
Sequence: MNAWNTIYDQFNPIAFSLGSIEVHWYGLAYACAIVTAFYMALRMIQKDPKRFPIERKEFESYFLWAELGIVLGARIGYILIYEPNSGYYLTHFWQIFNPFDSHGNFVGIRGMSYHGGLVGFLIASYLYSRKDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRIVPKDSHLGQIIGIMVDNELRYPSQLIEAFLEGVIVFLMVMWAKKHTKTHGLLIVVYGLGYSLMRFIAEFYREPDSQMGVYFLNLSMGQILSLFMVIVSLGILLYATKNSKKIKENQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: F16PA_METS4
Sequence: MGLGSRLDACLAREVAGGDRPIAAVLAALAEAAAGTGRLLRDGGADAGPDDLDAAVQARFVAALRETPTALLALPEAEAPLALMPDGAIAVALTPLDGRENLAGNQPAGTLFSLRPAAGAPFREPGRIQVAAGFVTYGPRTELAVTWGAGARIFTLDPSGAFRLSREAVAIPPTSTLYAIDAANARFWEAPMRAFVEDCLRGSEGPRGQDFAMGWCASLAVGAQRALCRGGVHILPGETRRGRANGATRLIHEAAPIALVMEAAGGAATDGRDARILDLPTLDLQQRTPLVFGSAEEVACVGKYHDGRRHTGARSPLFGQRGLLRA
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.