PharMolix/UniProtQA huggingface dataset:
Protein: NDPA_ENT38
Sequence: MSLDINQIALHQLIKRDEQTLELVLRDSLLEPTSTVTEMMAELHRVYSAKNKAYGMFNEESELAQSLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGIVLFCQYRYLAVEYLLVTVLNNLSSMRVNEQLDISSTHYLDINHADIVARIDLTEWETNPESTRYLTFLKGRVGRKVSDFFMDFLGASEGLNAKAQNKGLLQALDDFTAEAQLDKSERQNVRQQVYSYCSEQLQAGEEIELESLSKELAGVSEVSFQEFTADKGYELEESFPADRSTLRQLTKFAGSGGGLTVNFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGK
What are the official names of this protein?
Nucleoid-associated protein Ent638_2782.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CH10_CLOBM
Sequence: MNIRPLGDRVVIKRVEAEETTKSGIVLPGAAKEKPQVAEVIAVGPGGLVDGKEVKMELKVGDKVLFSKYAGNEVKIEGEEVTILKQDDILAVVEG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX35C_CTEON
Sequence: GKCGDINAPCKAECDCCGYTTCDCYWGN
What is the function of this protein?
Insecticidal neurotoxin that reversibly inhibits the N-methyl-D-aspartate (NMDA)-subtype of ionotropic glutamate receptor (GRIN) and inhibits inactivation of insect sodium channels (Nav).  In vivo, is highly toxic to insects.
What are the official names of this protein?
U15-ctenitoxin-Co1a, U15-CNTX-Co1a, Neurotoxin Oc M33-7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SMU1_CHICK
Sequence: MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKVWNVKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the spliceosome (By similarity).  Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity).  Required for normal accumulation of IK (By similarity).  Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity).
What are the official names of this protein?
WD40 repeat-containing protein SMU1, Smu-1 suppressor of mec-8 and unc-52 protein homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SMU1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus speckle. Note=Colocalizes with SRSF1 in nuclear speckles.
Protein: NDB45_LYCMC
Sequence: MKVKFLLAVFLIVLVVTDHCHALFGLIPSLIGGLVSAFKGRRKRQMEARFEPQNRNYRKRELDLEKLFANMPDY
What is the function of this protein?
Mutant mucroporin-M1: can inhibit Gram-positive bacteria at low concentrations and antibiotic-resistant pathogens.  Minimum inhibitory concentrations (MIC) are the following: MIC=12. 5 ug/ml against E. coli AB94012, MIC=100 ug/ml against P. aeruginosa AB93066, MIC=25 ug/ml against B. thuringiensis AB92037, MIC=25 ug/ml against B. subtilis AB91021, MIC=5 ug/ml against S. aureus AB94004, and MIC=5 ug/ml against the methicillin-resistant coagulase-negative Staphylococcus.  Also shows antiviral activities against measles (EC(50) of 7. 15 ug/ml), SARS-CoV (EC(50) of 14. 46 ug/ml), influenza H5N1 viruses (EC(50) of 2. 10 mug/ml), HIV-1, and hepatitis B virus.
What are the official names of this protein?
Mucroporin, Antimicrobial peptide 36.21, Non-disulfide-bridged peptide 4.5, NDBP-4.5.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: DF210_ARATH
Sequence: MKTIILFLTLLVISSSCTSIITKTMNSKETTYLDSPAVSPSIDQYLVDIHLGHSFLQGVMSFCYDCGKACFRRGKNLARCKKFVCRCTKSGIK
What are the official names of this protein?
Defensin-like protein 210.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PCKA_LEPIC
Sequence: MQAQTQVKGLKELGLEPSEIFHNLSYDEIYEHEKKNGETVVSSNGTMMVDTGIFTGRSPKDKYFVDEPSSNGNIWWSHINFKVSEAIFDELYKKCVNYLSHKKLYVFDGYAGANPETRVSLRVVSEKAWQHHFCTNMFLRPTKEELVGLDPEFTIINACGIKNENFKQHGMNSEVFVIFHLAKKICIIGGTEYGGEMKKGIFSVMNYKLPLQGILSMHCSANVGQDGDTALFFGLSGTGKTTLSTDPNRKLIGDDEHGWDDNGIFNIEGGCYAKVINLDPKTEPDIYEAIRKDALLENVVYDPQTKIVDYSSAAKTENTRVSYPIFHINNIQVPSKGGHPKTIIFLTYDAFGVLPPVSKLSIEQAMYHFLSGYTAKVAGTERGIKEPTATFSACFGAAFMTLHPTKYAKLLGEKMKKHNVRAYLMNTGLVGGSYGVGKRMNLPSTRKIIDEILNGNIEKSEFVTHPVFQVAYPKTISGVDSAILDPREAWTDKAAYDQTAKKLGEMFIKNFKQYAEGSKDFDFTAFGPKI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_CLOB6
Sequence: MDKEWLEVCIYTSSEALEAISGILYNTGVKGVSIEDPKDIEFKKKHPGDWDYFDETLLKVKDTAIVKGYYKEDDKFNEYLDYIKKSVSNLDQFGIDKGKGLVEVHKVNEEDWENNWKKYYKPTKVSNKIVIKPIWENYDKKQEEIIVELDPGMAFGTGTHETTRMCINALEKHIKEDRTVFDIGCGSGILSIAAAKLGAKHVIGVDLDPVAVKSSKENIKYNNLDNIEILEGNLMEVVEGRANIVVANIIADVIIFLTEGVKAFIEKDGYFIASGIINSRKEDVIKKLEETGFVIEEVREEGEWVCIVSKIN
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS1_PAPAN
Sequence: MAGQFRSYVWDPLLILSQIVLMQTVYYGSLGLWLALVDGLVRSSPSLDQMFDAEILGFSTPPGRLSMMSFILNALTCALGLLYFIRRGKQCLDFTVTVHFFHLLGCWFYSSRFPSALTWWLVQAVCIALMAVIGEYLCMRTELKEIPLNSAPKSNV
What is the function of this protein?
Involved in protein trafficking.  May serve as a receptor for ARFRP1 (By similarity).
What are the official names of this protein?
Protein SYS1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SYS1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RR7_CHLAT
Sequence: MSRRNAPKKRPISSDPIYRSRLVSMVISHILKNGKKSLAHRILYQAMKNIEEKTEKDPLKILQQAVLNATPLVEVKARRIGGSTYQVPREVKPERGTALALRWLLSSARKRPGRDMASKLTNELLDAANEVGNAIRKREETHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MNTS_ECOLI
Sequence: MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK
What is the function of this protein?
Required for repression of mntH by MntR.  May function as a chaperone that makes manganese more available by delivering it to the necessary cellular locations when manganese is limiting.
What are the official names of this protein?
Small protein MntS.
What are the subcellular locations of this protein?
Cytoplasm. Note=May be loosely associated with the inner membrane.
Protein: IMP09_NAUMA
Sequence: FTAASQTLEAGR
What are the official names of this protein?
Uncharacterized protein IMPP9.
Protein: MESI_LEUME
Sequence: MKKKYRYLEDSKNYTSTLYSLLVDNVDKPGYSDICDVLLQVSKKLDNTQSVEALINRLVNYIRITASTYKIIFSKKEEELIIKLGVIGQKAGLNGQYMADFSDKSQFYSVFDQ
What is the function of this protein?
Imparts immunity to mesentericin-Y105 to naturally sensitive host strains.
What are the official names of this protein?
Probable mesentericin-Y105 immunity protein.
What is the protein family that this protein belongs to?
Belongs to the immunity protein EntA family.
Protein: GUF1_ARATH
Sequence: MGSMYRASKTLKSSRQALSILFNSLNSNRQNPTCIGLYQAYGFSSDSRQSSKEPTIDLTKFPSEKIRNFSIIAHIDHGKSTLADRLMELTGTIKKGHGQPQYLDKLQVERERGITVKAQTATMFYENKVEDQEASGYLLNLIDTPGHVDFSYEVSRSLSACQGALLVVDAAQGVQAQTVANFYLAFEANLTIVPVINKIDQPTADPERVKAQLKSMFDLDTEDVLLVSAKTGLGLEHVLPAVIERIPPPPGISESPLRMLLFDSFFNEYKGVICYVSVVDGMLSKGDKVSFAASGQSYEVLDVGIMHPELTSTGMLLTGQVGYIVTGMRTTKEARIGDTIYRTKTTVEPLPGFKPVRHMVFSGVYPADGSDFEALGHAMEKLTCNDASVSVAKETSTALGMGFRCGFLGLLHMDVFHQRLEQEYGTQVISTIPTVPYTFEYSDGSKLQVQNPAALPSNPKYRVTASWEPTVIATIILPSEYVGAVINLCSDRRGQQLEYTFIDAQRVFLKYQLPLREIVVDFYDELKSITSGYASFDYEDAEYQASDLVKLDILLNGQAVDALATIVHKQKAYRVGKELVEKLKNYIERQMFEVMIQAAIGSKIIARDTISAMRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKRVGSVDIPHEAFQQILKVS
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PDXB_PHOLL
Sequence: MKILVDENMPYADQLFQQLGDVQAIPGRPVPEGVLDHADAFMVRSVTKVNEELLKGRAVKFIGTATAGTDHVDQSWLSQAGIGFSAAPGCNAIAVVEYVFSALMLLAERDNFELKDKVVGIVGVGNVGSRLAERLAVLGIRTLLCDPPRADRGDAGEFWSLEKLVKEADILTFHTPLNKSGPYKTHHLVDVELLSVLPDNRILINASRGEVIDNQALLTALKCGKKLRVVLDVWEPEPDLSLPLLELVDIGTPHIAGYTLEGKARGTTQVFEAYCEFLGQPRKVALSDLLPEPDFSRVTLHGNVTQSTLKRLMHLVYDVRRDDTPLRQVAGQKGQFDYLRKNYLERREWSSLTVCCDNRESAELLAALGFSTELI
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXA_TRIL1
Sequence: MSIGVVHEQTITFEAGIRLESGRILAPITLVYELYGTMNADCSNVIMVEHAWTGDAHLAGKRREDDPKPGWWDAIVGPGRLLDTDRYCVLCSNVIGSCYGSTGPASINPRTGKRYNLSFPVITVRDMVRAQELLLDHLGIRRLLCVMGGSMGGMQALEWATQYPERVASVVALATTPRPSPQAISLNAVARWAIYNDPTWKKGEYKHNPKDGLALARGIGHITFLSDESMWQKFERRFSAKDGLFDFFGQFEVERYLNYNGYNFVDRFDANCFLYLAKALDLYDVAWGYESMTDAFSRITAPIQFFAFSSDWLYPPYQTEEMVTCLQGLGKEVEYHLIQSAYGHDAFLLEHETFTPMVRSLLERVAP
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.  In vitro, can also use propionyl-CoA or butiryl-CoA as acyl donor.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_SALDC
Sequence: MANIKSAKKRAVQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAALKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: BGAL_VIBVU
Sequence: MTAFSEILQRRDWENPQSVNIHCLKAHSPLASFRDMAHARDGIHAQRQSLNGQWKFKLFDAPEQVDGQFTQADFNDAEWDEIPVPSNWQLQGYDKPIYANIKYPFDVNPPFVPSDNPTGCYRTRVSLSPEDLLNTQRIIFDGVNSAFHLWCNGTWVGYSQDSRLPAEFDLTSHLVAGENTLAVMVMRWCDGSYLEDQDMWWLSGIFRDVTLLSKPQHCIEDVFITPELDACYRDGSLSIVTTIAAPETYQVQVQLFEGTQAVTEPNIARPHNRRIDERGTWNDDVVFQTLHLREPKKWTAETPNLYRLVVSLLDENGTHLESEAYPVGFRKVEISEGQLKLNGKPLLIRGVNRHEHHPELGHVMTEEDMIRDICLMKQYNFNAVRTAHYPNHPRWYELCDQYGLYVCDEANIETHGMQPMSRLSSDPQWAHAYMSRYTQMVLRDKNHPSIIIWSLGNESGHGSNHNAMYAWSKNFDPSRPVQYEGGGSNTTATDIIAPMYARVNTLVADEAVPKWPIKKWISLPNETRPLILCEYAHAMGNSLGSFDEYWAAFREFPRLQGGFIWDWVDQGLSQWDENGQHFWAYGGDFGDEINDRQFCINGLIFPDRTVHPTLQEAKYCQRMITVSLQEQTQKACTLLVTNENLFRTTDNEQLNWSLLENGQVIQTGSQVLSVEADSQTRLEIALNFTPKAQAQYYLNTDICLIEATSWAPAGHVVATEQMALRNHAGLAMPTLRTQPAPKLTENGHAIVVSSLDEKHQWRWDSQSGLLMEWNVDGKAQMLAAPQDNFFRAPLDNDIGISEVDNVDPNAWVCRWEMAGIGQWERHCVQCESETLAHAVVVTTTFAYHFGGDVQAITQWTHTLSNDGEMLLDVDVTLADALPPMPRIGLELQLPLHQADTPITWQGLGPFENYPDRLAAARFGLHTQTLAQMHTPYIFPTDSGLRCGTQWLQVNELAISGDFQFSVSQYAQQQLAEAKHTHDLLAQERIYLRLDHQHMGVGGDDSWSPSVHKEFQLTEKHYRYQLRFSPASR
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: BUD32_CANGA
Sequence: MSQEIVDRVRNYLSPNIPVTPISQGAEAVVFTTSVHPYLPENCNSNEKYIIKYRSPKRYRHPVIDKSLTKHRTLGEARLLSKLYTIEGLHVPKLIACDAYNGYLWLEFLGEDLPENFGYSNLKNFLWMYDAKNDPYCEVVKRALIEVGEQIGKLHWNDYCHGDLTSSNIVMVHSDTDSHHWVPHLIDFGLGSTTTMVEDKGVDIYVLERAILSTHSQHAEQYIEWMLDGFKSVYEKNGKLGKKKLDELLKRFAEVRLRGRKRSMIG
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
EKC/KEOPS complex subunit BUD32, Atypical serine/threonine protein kinase BUD32.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: RPOB_FERNB
Sequence: MKTYQIGKRTRYSFGKVDEIIQVPDLVEIQRKSFEELLNHGILRILKKFSPITSAKVEGRREKGFNLEFVNFRVGAPLHSVEECKQRLLTYVAPFYATVRVTDVSTGEMREEEVSLGNYPIMTENQTFVINGVERVVVSQLVRSPGVYFVEEPTKNIGAKPIYLAHFLPVRGVWLEIMLNLNDETLYARIDRRKRLNLFLVLKTLGFQNDIDILSLFPAYLDVEDDYSLKQSEGIIILEKIVSKSGEVIAEKGSVLTSTLVEILREHGIEKIKVVNNYMFKTYMKLKEKLKMPLEENISELRAFMEIYKELRPGEVFRYNAAKSYWNNLYFNEERFELSEVGRYKMNKKLTNAYRKYLIEIEGRNPKSVERIEYEEKSNALTPIDIILVIRMLLETEKHPETLDTKDHLSNKRVKTVGELIGSEFERAFSKSIHQIQEKLATYTSLDKISIPSLINLRNVIASLNSFFATNPLSQFMDQVNPIAELTHKRRLTAVGPGGLKRERARFEVRDVHHSHYGRMCPIETPEGGNIGLITSLSVYATIDEYGFLVTPYRRITNGKLANEVVYLAADEEENYKIASVTIAFDKEGNIIQERVPVRYLEKIVYVHKNEVDLVDISPKQIVSVTTSLIPFLEHDDANRALMGSNMQRQAVPVIKPEAPFVGTGMEYAAAIYSGHVVLAKNDGVVKKVDGRKIIIHRIDENGQLMYDKKGNPIIDEYTLLKYVRSNQDTSITQKPIVNVGDFVKKGSPIADGPATDNGELALGKNVLVAFLPWEGYNFEDAILVSEELLEEDTFTSVHIEVYETTARETRVGPEEITSEIPNVSKENIRNLDENGIIRIGAYVGKQKYFTSQDILVGKVTPKGESDASPEEKIMRSVFGEKGKDVKDSSLRVPHGVEGRVIGVHVFHKEEVGDLGPGVNTLVRVYLATRKPLEVGDKLAGRHGNKGVVSMILPKEDMPFLPDGTPVQVVLSPLGVPSRMNIGQVLETSLGWLAKLTNRYFATPVFDGAKEDDILPELYKVRETLNLHHGDDPNNPSGKVTLRDGRTGKEFDFPVLVGYMYIMKLIHIARDKIHARATGPYSLIHQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLNEMLTVKSDDIKGRTEVYKAIMKSKNLPEPGLPESFKVLVRELKGLALDVRVYDEHGNEIDIEKL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: HMSDV_HUMAN
Sequence: MEIFIEVFSHFLLQLTELTLNMCLELPTGSLEKSLMISSQVLQIPVANSTKQR
What is the function of this protein?
This splice variant of HMSD is the precursor of the histocompatibility antigen ACC-6.  More generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells.  The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing.  The binding of these peptides to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation from HLA-identical sibling donor.  GVHD is a frequent complication after bone marrow transplantation (BMT), due to mismatch of minor histocompatibility antigen in HLA-matched sibling marrow transplants.  However, associated with GVHD, a favorable graft-versus-leukemia (GVL) can be induced by donor-recipient disparities in mHags.  ACC-6 is presented to the cell surface by MHC HLA-B*4403.  This complex specifically elicits donor-cytotoxic T-lymphocyte (CTL) reactivity against hematologic malignancies after treatment by HLA-identical allogenic BMT.  It induces cell recognition and lysis by CTL.  Immunogenicity of most autosomal mHags results from single-nucleotide polymorphisms that cause amino-acid substitutions within epitopes, leading to the differential recognition of peptides between donor and recipient.
What are the official names of this protein?
Minor histocompatibility protein HMSD variant form, HSMD-v.
Protein: PUCC_RHOSU
Sequence: MNRLSKMAVNRIATVGPRFLPFAEAASEDLPLSRLLRLSMFQVSVGMAMVLLVGTLNRVMIVELEVPASIVGIMISLPLLFAPFRALIGFKSDTHKSALGWRRVPYIWKGTLLQWGGFAIMPFALIVLSGQESAAGAPEWIGILSAAVSFLLVGAGVHTVQTVGLALATDLAPREDQPNVVGLMYVMLLVGMIVSALLFGMWLEDFYHAKLIKVIQGAAVATMVFNVIALWKMEARDRVRARQRLEGDPEPSFREAWGLFTRGPNARRLLWVIGLGTLGFGLSDVLLEPFGGQVLDMSVAATTKLTAAVAGGTLVGFAWASRVLSRGYDPMAMAGWGAVVGLPAFAIITFSATLQSEPVFVFGTMMAGFGAGLFSHGTLTATMRSAPKAQVGLALGAWGAVQATSAGAGIALGGVFRDAVRIRRSAISSARRPYSLSTRSNWRCWSRPSSSATG
What is the function of this protein?
PucC is required for high-level transcription of the puc operon.
What are the official names of this protein?
Protein PucC.
What is the protein family that this protein belongs to?
Belongs to the PucC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DEK1_ORYSJ
Sequence: MEEEEHRGVVLVCSICGFLFAVLGPLSFWILWAVNWRPWRLYSWIYARKWPAYVQGPQLSTLCSFFTLFAWLVVVSPITVLLVWGGILIALLERNIIGLAVIMVGVALLLSFYSIMLWWRTQWQSSKAVAYLLLLAVGLLCAYEFCAVYVTTGASASELNSPSGFFFGVSAISLAINMLFISKILFNGSGFDVDEYVRRLYKFAYSDCVEVAPVSCSPDPPDPSELYMTKSSRVLHLGLLYLCSLMVLVVYSILYGLTSKEARWLGALTSVAVVILDWNLGLCSFRFELLKSRMIALFVAGTSRVFLICFGVHYWYLGHCISYAFVASVLLAAAVSCWLSISNPSVARIDALRSTVIKLREGFRRKGQTSSSNSSDGCGSSVKRSSGSVEAGPHGNATDSMYRSNSQSDCVNWNNVPFDRSNSCQEGQSSDKNIDSGRASLAHRSNSCLSAVAVQDPETAVVSADRHGDPTASLVVCSSSGLESQGCESSGSATASGNQQLLDLNLAAIFQDRLNDPRITSMLKRNGGLGDVELANLLQDKGLDPNFSYMMKDKVMDPRILALLQRSSLDADREHQDDVDVTGTDSDRLDTTIANQISLSEELRRSGLENWLNLSRLMFHQVAGSPIRAFVVFTLIFIIETVTVAVHRPKPIKVINATHEQFEFGFSILLLSPVVCSIMAFIWSLCAEEMTMTSKPRKYGFIAWLLSTCVGLLLSFLSKSSVILGLSLTVPLMVACLSFAIPIWMRNGYRFWIPGGELDSRENIRQAPGKKERALFAISITVFTASVIGLGAIVSAKPLDALGYKGWDADKKSFYSPYATSMYLGWALSSTIAVLATGVIPIVAWFATYRFSPSSAICVGLFATVLVSFCGVSYWGVVNSRQDGVPLKADFLAALLPLLCIPAVFSLFTGMYKWKDDDWKISRGVYLFVGMGVLLLLGAISAVIVTIRPWTVGVACLLVILFLVFAIGVIHYWTSNNFYLTRTQMLLVCSLAFLLALAAFLMGLFQEKPFVGASIGYFSFLFLLTGRALTVLLSPPIVVYSPRVLPVYVYDAHADSAKNVSYAFLILYGIALATEVWGVIASLILNPPFIGAAISAITLVIAFSFAVSRPCLTLKMLEDAVHFLSKDTVVQAMSRSANKTRNAISGTYSAPQRSASSAALLVGDPAITLDRAGNFVLPRADVMKLRDRLRNEEITAGSFFCGVKNCLMIGSPVDVDYRRNMCAHARILALEEAIDTEWVYMWDKFGGYLLLLLGLTAKAEQIQDEVRLRLFLDSIGLSDLSAKEIKKWMPEDRRHFELIQESYIREKEMEEEVLMQRREEEGKGRERRKALLEREERKWKELEISLLSSIPNAGSRDAAAMAAAVRAVGGDSALEDSFARDRVSSIARHIRKAQLARRAEQTGIPDTVCILDDEPRSTGRHCGEIDLCLCESKKVSFSIAVMVQPVSGPVCLFGTEFQKKVCWEILVAGSEQGMEAGQVGLRLVTKGERMTTVAKEWNIGASSIADGRWHLVTVTIDADLGEATSFIDGVYDGYQNALPLPRNNGIWEPGTDIWVGARPPTDLDAFGRSDSEGSDSKMQIMDAFLWGRCLTEDEVAMLHTAICSAEYGLFDLAAEDAWHGSYSARVDDWESEEANFELYDQEDVEWDGQYSSGRKRHARDSVAIDIDSFARRPRKPRFETREEVNQRMLSVERAVREALIAKGERNFTDQEFPPDDRSLFVDPMNPSLKLQVVSEWMRPSDIAKEVSISSQPCLFSGSVNSSDVCQGRLGDCWFLSAVAVLTEMARISEVIITPEYNEEGIYTVRFCIQGEWVAVVVDDWIPCESPGKPAFATSRKQNELWVSILEKAYAKLHGSYEALEGGLVQDALVDLTGGAGEEIDMRSPQAQIDLASGRLWSQLLHFKQEGFLLGAGSPSGSDAHISSSGIVQGHAYSILQVREVDGHKLVQIRNPWANEVEWNGPWSDSSQEWTERMKHKLKHVPQSKNGVFWMSWQDFQIHFRSIYVCRVYPPEMRYSVHGQWRGYSAGGCQDYDSWHQNPQYRLRVTGRDALYPVHVFITLTQGVGFSRKTNGFRNYQSSHDSSMFYIGMRILKTRGCRAAYNIYMHESVGGTDYVNSREISCELVLEPYPKGYTIVPTTIHPGEEAPFVLSVFTKAPIKLEAV
What is the function of this protein?
Essential protease involved in epiderm development.  Required for aleurone cell development in the endosperm probably by maintaining and restricting the aleurone and embryonic epidermal L1 cell-layer fates as well as meristems organization.  Involved in the maintenance of adaxial/abaxial axis information in developing leaves, probably by regulating cell proliferation and expansion.  Does not need calcium ions to be active.
What are the official names of this protein?
Calpain-type cysteine protease ADL1, Phytocalpain ADL1, Protein ADAXIALIZED LEAF1, Protein DEFECTIVE KERNEL 1, OsDEK1, Protein SHOOTLESS 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasm. Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.
Protein: Y7756_PARXL
Sequence: MLLHIPNVLNAEQLRIVRERLDTAGDAWVDGRATAGYQGAPVKRNQQIAEHTPIARELGDVILASIERNPLFISSVLPNQVYPPLFNRYEGGMQFGSHVDGAVRVLPNGVKLRTDVSVTLFISDPADYDGGELVIEDTYGVQQVKLPAGDMIVYPATSLHQVTPVTRGVRVASFFWVQSLVRSDTQRAMLFDMDTAIQRLNATNADDAARRSLVGIYHNLLRTWSEP
What are the official names of this protein?
PKHD-type hydroxylase Bxeno_B2756.
Protein: ENCP1_PYRFU
Sequence: MLSINPTLINRDKPYTKEELMEILRLAIIAELDAINLYEQMARYSEDENVRKILLDVAREEKAHVGEFMALLLNLDPEQVTELKGGFEEVKELTGIEAHINDNKKEESNVEYFEKLRSALLDGVNKGRSLLKHLPVTRIEGQSFRVDIIKFEDGVRVVKQEYKPIPLLKKKFYVGIRELNDGTYDVSIATKAGELLVKDEESLVIREILSTEGIKKMKLSSWDNPEEALNDLMNALQEASNASAGPFGLIINPKRYAKLLKIYEKSGKMLVEVLKEIFRGGIIVTLNIDENKVIIFANTPAVLDVVVGQDVTLQELGPEGDDVAFLVSEAIGIRIKNPEAIVVLE
What is the function of this protein?
Fusion of the shell and cargo protein of a type 1 encapsulin nanocompartment (PubMed:17397865).  The nanocompartment is probably involved in iron storage (Probable).  Expression in E. coli generates spherical particles (PfSPs) about 30 nm in diameter (PubMed:16091594).
What are the official names of this protein?
Ferritin-like-encapsulin shell fusion protein, Type 1 encapsulin shell protein, Virus-like particle.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the encapsulin family. Family 1 subfamily.
What are the subcellular locations of this protein?
Encapsulin nanocompartment.