PharMolix/UniProtQA huggingface dataset:
Protein: CYB_HYPAP
Sequence: MINIRKTHPLMKIINNTFIDLPTPSNISSWWNFGSLLGLCLITQILTGLFLAMHYTPDTTTAFSSIAHICRDVNYGWVIRYLHANGASMFFICLYAHIGRGLYYGSYIFLETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFALHFILPFIILALAIVHLLFLHETGSNNPTGIPSDMDKIPFHPYYTIKDTLGALLLILVLLTLTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILLFIPLLHTSKQRSMMFRPFSQLLFWLLIADFLTLTWIGGQPVEHPYMIMGQLASMLYFLLILVLMPMASLIENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Z280D_HUMAN
Sequence: MGDNPFQPKSNSKMAELFMECEEEELEPWQKKVKEVEDDDDDEPIFVGEISSSKPAISNILNRVNPSSYSRGLKNGALSRGITAAFKPTSQHYTNPTSNPVPASPINFHPESRSSDSSVIVQPFSKPGYITNSSRVVSNKSSELLFDLTQDTGLSHYQGGPTLSMAGMSESSFLSKRPSTSEVNNVNPKKPKPSESVSGANSSAVLPSVKSPSVTSSQAMLAKGTNTSSNQSKNGTPFPRACPKCNIHFNLLDPLKNHMKYCCPDMINNFLGLAKTEFSSTVNKNTTIDSEKGKLIMLVNDFYYGKHEGDVQEEQKTHTTFKCFSCLKILKNNIRFMNHMKHHLELEKQSSESWENHTTCQHCYRQFPTPFQLQCHIESTHTPHEFSTICKICELSFETEHVLLQHMKDNHKPGEMPYVCQVCNYRSSSFSDVETHFRTSHENTKNLLCPFCLKVIKIATPYMHHYMKHQKKGIHRCTKCRLQFLTCKEKMDHKTQHHRTFIKPKQLEGLPPGTKVTIRASVGPLQSGASPTPSISASASTLQLSPPRTKNITAKNPAKSNTSKPNTVKSNASKPNTSKPNGSKSKYKPKISNMQKKQSTLASSNKKSKVNTALRNLRYRRGIHKCIECCSEIKDFANHFPTYVHCSFCRYNTSCSKAYVNHMMSFHSNRPSKRFCIFKKHSENLRGITLVCLNCDFLSDVSGLDNMATHLSQHKTHTCQVVMQKVSVCIPTSEHLSELKKEAPAKEQEPVSKEIARPNMAERETETSNSESKQDKAASSKEKNGCNANSFEGSSTTKSEESITVSDKENETCLADQETGSKNIVSCDSNIGADKVEKKKQIQHVCQEMELKMCQSSENIILSDQIKDHNSSEARFSSKNIKDLRLASDNVSIDQFLRKRHEPESVSSDVSEQGSIHLEPLTPSEVLEYEATEILQKGSGDPSAKTDEVVSDQTDDIPGGNNPSTTEATVDLEDEKERS
What is the function of this protein?
May function as a transcription factor.
What are the official names of this protein?
Zinc finger protein 280D, Suppressor of hairy wing homolog 4, Zinc finger protein 634.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMN6_VIBA3
Sequence: MKDKTINTKSFNFKRFSIYGGQSGMPVSTDGVLLGSWINLAPESLVLDIGTGTGLLALMAAQRFEDALISAIDIDQHAIDAATVNIEQSPWQDRISLHHDSVLTTDFSQRFDAIICNPPYFNSGEQAQQSQRATARHTDSLDHLQLAQRCFEITTDAATASFILPTPEGEGFIKLAEQCGWYLAKRLDVKTTDKKPASRILFELSKDPVCGQDLQRESLTIHHQGGYSEAFIALTKDFYLKM
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIC8_CAEBR
Sequence: MPGDQLTEETIQRVFLNATSAKIEEFFSKWNFSNANSTKFGMSEAERNLLGDEISAKIDNDDLASILLETVRLISRERQGLESLLNENLCDTILKLAGITPVVGYPRSVHALMEAQKCLVNTMFHSAKMRERFYMNLVNGDQIQRFLSEFEDSRRENSNIQWIREMNPTQAAEVWYFYHRIAFIATAMDKGFQRHWADQSTTVSNILCAAEVCLQKASDDVANLDLLRANEAMKTFFNVFCHFHGDVPGLDEKNTHLACRILRDVICSGIPNDDVIQSAIHALSVPPLPMDLSVLLSDPNFPIVPLPETISEEERVHPRDYYVNMTLTEAILAALDKQLIKAVDLLNSVPFNQVSPEGNTLVDLSGPYFQALARLCVESKYARRYCRIRVLPPLVADEVKKRPEEHDSLRGRIVRVMMLPSTTKEVASEFLFIICKRSVSRMIKYVGFGHSAGHLANFGLLGQINQPKHASDSEDSETEDYNAVKDNVNPVTGAMYPPDHGSAMDGMSDAQKEFEAMKLVDAMNKLMDQGLVKPGTIGDDGKVREVSHVLELLKDAPEPDTMDSDSD
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins independently of G-protein coupled receptors.  Acts by exchanging bound GDP for free GTP.  Also able to activate the G(s)-alpha in synaptic signaling network.  Plays a key role in asymmetric spindle positioning, a step for asymmetric cell division that generates cell diversity during development by activating G(i) alpha protein goa-1 and gpa-16 independently of G-protein coupled receptors (By similarity).
What are the official names of this protein?
Synembryn, Resistance to inhibitors of cholinesterase protein 8.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the cell cortex.
Protein: BFRH_ABSSP
Sequence: MRGNPEVIDYLNMLIGGELAARDQYLIHSRMYEDWGLTKY
What is the function of this protein?
May perform analogous functions in iron detoxification and storage to that of animal ferritins (By similarity).  Contains approximately 750 iron atoms per molecule.
What are the official names of this protein?
Bacterioferritin heavy chain, BFR.
What is the protein family that this protein belongs to?
Belongs to the bacterioferritin family.
Protein: IHFB_BORPD
Sequence: MTKSELIAALAARYPQLAARDTDYAVKTMLDAMTQALASGQRIEIRGFGSFSLSQRSPRVGRNPKSGEQVLVPGKQVPHFKAGKELRERVDLAGGLADTQPDGDAPDQPQPTLLGLHAM
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: YQGE_ECOLI
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKTPIADRWREAAKLIGVDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: DRE2_PLAYO
Sequence: MINFSNTLVILNNDVPCELLKKKYSELLIPTISILDFKKKKIYKKYNNIFLYSYQNYSFLLDLNDNILLKIQKYLNKNGILDINLYLNDKNNNNNSGTNKKDHSKIEDISQILKKLRKECLYNGYINISTEQTTSENGIVINIKAENPDFNKSDDDNNLVSSDEEIYEKCEDKKKVVNRVCDNCTCGKKEKAMNLEKIKINDNEVEYSTENVVSSCGNCYLGDAFRCGSCPYKGLPAFQPGENVKLNLNVC
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: TMC5_RAT
Sequence: MSSFHKNSSYMEDPDYPGYSGSQNHTQNYLRTQDDLEFPGCLDNPGFHHPRRNPYSSDSRTNPDYHHSLAEPDYPGSPSDADYQNTRCHPRSAHPRTRPDYEPDYEPDYNDFQSESYHPDLSMEPDYPGSHGHPGFAGVRSSVNSTGPRTNLGYLDLEEPDYPGAQGNSYHSGPRSHSNLPGSRRNAGYAGSRINSYPDSLGEPDYPGAENQPNSPDFYGKPDYPGAEEGDVYSPSKTLGVIGRSRGSFGILGREDGDYPEGIEMASLGMAGDPRNGYVNPAYMRGSSPVCPDRNLLLCARDWNTSPQGQKLIASLVPMTSRDRIKTIRNQPRTMQEKRELRKIVDKEKNKQSHGTFEANCCAQCLSSLSLAYRRTKSSLSELLNYISLWQKRFKVIGGKFGTSVLSYFSFLRWLLKFNIFSFVMNFSFIIIPQFTVGEKNTLQFTGLEFFTGAGYFRETVMYYGFYTNSTIRHRMGGASYNMQLAYIFTIGACLVICFFSLLFSMAKYFRNNFINPHIYSRGIAKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSEIRQENDRLTLNQKLTRFSVHVAAWLVSTGITAACCVAVYYLAEYNSEFLKTHKNPGAVLLLPFVVSCINLAVPRFYSMFRLVERYEIPRQEVYVLLIRNIFLKISIVGILCYYWLNIVALSGEECWETLIGQDIYRLLLMDFVFSLADSLLGEFLRRLIGMKFITSLSLQEFDIARNVLELIYAQTLAWLGIFFCPLLPFIQMITLFIMFYVKNVSLMMNFQPPSKAWRASQMITFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPSFIQSIYSWIDTLSHRPGYLWVVWIYQNLIGSVHFFFILTLIVLIITYLYWQITEGRKVMIRLLHEQIINEGKDKMFLIEKLTKLQDIERRANPSTLVLERREVEQQSPLHLEELDAAPDLRLRRSMQEENAIA
What is the function of this protein?
Probable ion channel.
What are the official names of this protein?
Transmembrane channel-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the TMC family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEPA_STAAM
Sequence: MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: STA13_MOUSE
Sequence: MFSQVPRTPAAGCYYLNPLTPESQEMYLRFDQTARRSPYRMSRILARHHLVTKIQQEIEAKEACDWLRAAGFPQYAQLYEDSQFPINIAAVKKDHDFLERDLVEPLCRRLNTLNKCASMRLDVNFQRKKGDDSDEEDLCISNKWTFQRTSRRWSRVDDLHTLFPVADRNGSPGGPRMRNTASSESVLTDLSEPEVCSIHSESSGGSDSRSQSGHHSADSTHALEATLVSSSLPQSTREGLNQSFHPKNEKPTRTRAKSFLKRMDTLRVKGALGRHKGPGRTGGLVISRPVLQQEPESFKTMQCVQIPNGDLQTSPPAACRKGLPCSSKSSGESSPLENSSTVSTPCMKERKCHHEANKRGGMYLEDLDVLAGTALPDTSDQNHMHGFHSQENLVVHIPKDHKPGTFPKALSIESLSPTDNSNGVNWRTGSISLGRQQGPGMREPRLMSSCHRASRVSIYDNVPSSHLYASTGDLLDLEKDGLLPQLDDILQHVNGIQEVVDDWSKNILPELQSHSTLAGDPGLSPFPSPNQVTLDFEGNSVSEGRTTPSDVERDRTSLNESEATGVRERRDSGVGASLTRPNRRLRWSSFQLSHQPQPSPATPHISSQTAAQLNLLQRFSLLRLTAIMEKYSMSNKHGWTWSVPKFMKRIKAPDYRDKAVFGVPLIVHVQRTGQPLPQSIQQALRYLRSNCLDQVGLFRKSGVKSRIHALRQMNENFPDNVSYEDQSAYDVADMVKQFFRDLPEPLFTNKLSETFLHIYQYVPKEQRLQAVQAAILLLADENREALQTLLCFLHDVVNLVDENQMTPMNLAVCLAPSLFHLNLLKKESSPKVIQKKYATGKPDQKDLNENLAAAQGLAHMITECNRLFEVPHEMVAQSRDSYLEAEIHVPSLEDLGAQLAESGATFHTYLEHLVQGLQKEAKEKFKGWVTCSSPDNTDLAFKKVGDGHPLKLWKASVEVEAPPSVVLNRVLRERHLWDEDFVQWKVVERLDKQTEIYQYVLNSMVPHPSRDFLVLRTWKTDLPKGMCTLVSLSVEYEEAQLMGGVRAVVMDSQYLIEPCGSGKSRLTHICRIDLKGHSPEWYSKGFGHLCAAEVTRIRNSFQPLVAEGPETKI
What is the function of this protein?
May function as a GTPase-activating protein.
What are the official names of this protein?
StAR-related lipid transfer protein 13, START domain-containing protein 13, StARD13.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet.
Protein: ISCA1_HUMAN
Sequence: MSASLVRATVRAVSKRKLQPTRAALTLTPSAVNKIKQLLKDKPEHVGVKVGVRTRGCNGLSYTLEYTKTKGDSDEEVIQDGVRVFIEKKAQLTLLGTEMDYVEDKLSSEFVFNNPNIKGTCGCGESFNI
What is the function of this protein?
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.  Probably involved in the binding of an intermediate of Fe/S cluster assembly.
What are the official names of this protein?
Iron-sulfur cluster assembly 1 homolog, mitochondrial, HESB-like domain-containing protein 2, Iron-sulfur assembly protein IscA, hIscA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CCCR_CERS4
Sequence: MALDVQSDIVAYDAPKKDLYEIGEMPPLGHVPKEMYAWAIRRERHGEPDQAMQIEVVETPSIDSHEVLVLVMAAGVNYNGIWAGLGVPVSPFDGHKQPYHIAGSDASGIVWAVGDKVKRWKVGDEVVIHCNQDDGDDEECNGGDPMFSPTQRIWGYETPDGSFAQFTRVQAQQLMKRPKHLTWEEAACYTLTLATAYRMLFGHKPHDLKPGQNVLVWGASGGLGSYAIQLINTAGANAIGVISEEDKRDFVMGLGAKGVINRKDFKCWGQLPKVNSPEYNEWLKEARKFGKAIWDITGKGINVDMVFEHPGEATFPVSSLVVKKGGMVVICAGTTGFNCTFDVRYMWMHQKRLQGSHFANLKQASAANQLMIERRLDPCMSEVFPWAEIPAAHTKMYRNQHKPGNMAVLVQAPRTGLRTFADVLEAGRKA
What is the function of this protein?
Catalyzes the NADPH-dependent reductive carboxylation of crotonyl-CoA ((2E)-butenoyl-CoA) to (2S)-ethylmalonyl-CoA, in the presence of CO2 (PubMed:17548827, PubMed:18819910, PubMed:19458256).  This is a key reaction in the ethylmalonyl-CoA pathway for acetyl-CoA assimilation required for R. sphaeroides growth on acetate as sole carbon source (PubMed:17548827, PubMed:22056933).  Is also able to accept acryloyl-CoA as an alternative substrate, yielding (2S)-methylmalonyl-CoA (PubMed:18819910, PubMed:19458256).  To a lesser extent, when CO2 is absent, the enzyme also catalyzes the reduction of crotonyl-CoA to butanoyl-CoA (PubMed:17548827, PubMed:19458256).
What are the official names of this protein?
Crotonyl-CoA carboxylase/reductase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Crotonyl-CoA carboxylase/reductase subfamily.
Protein: ENV_CAEVC
Sequence: MDAGARYMRLTGKENWVEVTMDGEKERKREGFTAGQQGKYNPQVSKNIGNRNTNDCFAYKGIFLWRISLTMWILLGINMCVSAEDYITLISDPYGFSPIKNVSGVPVTCVTKEFAKWGCQPLGAYPDPEIEYRNVSQEVVKEVYQENWPWNTYHWPLWQMENVRYWLKENMQENQQRKNNTKEGIEELLAGTIRGRFCVPYPFALLKCTKWCWYTAAINNESGKAGKIKINCTEARAVSCTEDMPLASIQRAYWDEKDRESMAFMNIKACDSNLRCQKRPGGCMEGYPIPVGAEIIPESMKYLRGAKSQYGGIKDKNGELKLPLTLRVWVKLANVSEWVNGTPPDWQDRINGSKGINGTLWGELNSMHHLGFALSQNGKWCNYTGEIKLGQETFQYHYKPNWNCTGNWTQYPVWQVIRNLDMVEHMTGECVQRPQRHNITVGNGTITGNCSTTNWDGCNCSRSGNYLYNSSEGGLLLILCRQNSTLTRILGTNTNWTTMWGIYKNCSGCENATLDNTGEGTLGGVANKNCSLPHKNESNKWTCAPRQRDGKTDSLYIAGGKKFWTRIKAQFSCESNIGQLDGMLHQQILLQKYQVIKVRAYTYGVIEMPENYAKTRIINRKKRELSHKRKKRGVGLVIMLVIMAIVAAAGASLGVANAIQQSYTKAAVQTLANATAAQQDVLEATYAMVQHVAKGVRILEARVARVEAITDRIMLYQELDCWHYHQYCITSTKTEVAKYINWTRFKDNCTWQQWERGLQGYDTNLTILLKESAAMTQLAEEQARRIPEVWESLKDVFDWSGWFSWLKYIPIIVVGLLGCILIRAVICVCQPLVEIYRTLSTPTYQRVTVIMETRADVAGENQDFGDGLEESDNSETSERVTVQKAWSRAWELWQNSPWKEPWKRGLLRLLVLPLTMGIWINGWLGEHHKNKKRKGGLETWHKKGTDIGLGQIPVDHLWCYKKSKSL
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N- terminus of Gag (By similarity).
Protein: RUVA_PROMT
Sequence: MISWLKGEKVHTWKISSRKGVVLNVGGVGYEIQLLPKQIDKAEVLNEFELWIHQIDREDGTSLYGFIEVNQRDLFREIISVNGIGPQIGMAMLEEFEVPQLVNAIENKESNLLTKTQGIGKRIAERLIVELRNKLQRFTDNDKTIHENKNDIEANQFSKYIDEIYLILNSLGYVDNEIKESIKIITINEKENSLLLNSSSAEEKADLMDKHLKEILMKLSEKST
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: Y3906_YERPS
Sequence: MSAIALTVSMLALVAVLGLWIGNWKIYGVGLGIGGVLFGGIIVGHFAQTYQIVLNGDMLHFIQEFGLILFVYTIGIQVGPGFFSSLRVSGLRLNCFAILMVVVGGLVTAIIHKLFAVPLPIILGVFSGAVTNTPALGAAQQILTDLGSPPQLVSQMGMGYAMAYPFGICGILLVMWLIRLFFKINIDREAKAFDSSYGQNRELLQTMNVAVRNPNLHGLSVQDVPLLNSDEVVCSRLKRGDLLMVPMPATVIEIGDYLHLVGQRDALEKVRLVVGEEVDVTLSTAGTALQTARVVVTNEAVLGKKIRDLNLKQKYDVVITRLNRAGIELVASNSANLQFGDILNLVGRPEAIEAVSAIVGNAQQKLQQVQMLPVFIGVGLGVLLGSIPLFVPGFPAALRLGLAGGPLVVALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFINTLVNGDGLAWIGYGAMITGIPLLTVGILARMLVKMNYLTLCGMLAGSMTDPPALAFANGLHPTSGAAALSYATVYPLAMFLRIMSPQILAVLFWTL
What are the official names of this protein?
Putative transport protein YPTB3906.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CASA1_RAT
Sequence: MKLLILTCLVAAALALPRAHRRNAVSSQTQQENSSSEEQEIVKQPKYLSLNEEFVNNLNRQRELLTEQDNEIKITMDSSAEEQATASAQEDSSSSSSSSEESKDAIPSATEQKNIANKEILNRCTLEQLQRQIKYSQLLQQASLAQQASLAQQASLAQQALLAQQPSLAQQAALAQQASLAQQASLAQQASLAQKHHPRLSQVYYPNMEQPYRMNAYSQVQMRHPMSVVDQAQFSVQSFPQLSQYGAYPLWLYFPQDMQYLTPEAVLNTFKPIAPKDAENTNVW
What is the function of this protein?
Important role in the capacity of milk to transport calcium phosphate.
What are the official names of this protein?
Alpha-S1-casein, Alpha-casein.
What is the protein family that this protein belongs to?
Belongs to the alpha-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRAS1_URTCR
Sequence: MKLFLVSIVLVGMLVLAAARPERDIDSFDEQEEKGFVKRGASCDCHPFVGTYWFGISNCPSGHGYRKKCASFFGVCCVK
What is the function of this protein?
Peptide with both antimicrobial and neurotoxin activities.  Cationic AMP with antibacterial activity against both Gram-positive bacteria (B. subtilis, MIC=11. 49 ug/mL) and Gram-negative bacteria (E. coli (MIC=12. 21 ug/mL) and S. enterica (MIC=11. 95 ug/mL)) (PubMed:28796463).  Shows no significant antimicrobial activity against bacteria S. aureus and P. aeruginosa, as well as the fungus C. albicans (PubMed:28796463).  In vivo, induces reversible paralytic activity towards the shrimp P. paucidens (PubMed:28796463).  May act by impairing sodium or potassium channels in the prey (Probable).
What are the official names of this protein?
Crassicorin-I, BDS-like antimicrobial peptide, BDS-like AMP.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: RLPH2_ARATH
Sequence: MAQKPRTVICVGDIHGYISKLNNLWLNLQSAIDPSDFSSALVIFLGDYCDRGPETRKVIDFLISLPEKHPDQTHVFLAGNHDFAFSGFLGLLPRPSDGSDLKDTWKEYSKSEETEGWYTGEGFEDMHLQGRRWAGKIKATFNSVKGMAYKGSIYDAGSTFESYGVPHGSSDLMKAVPESHKKFLTNMVWVHEEDDVCIETEEGLKHCKLIAVHAGLEKGNNVEEQLKLLRAKDTSISKIQHLSGRKNVWDIPQELDDKHTVVVSGHHGKLHIDGMRLIIDEGGGFPDKPVAAIVLPSKKIIRDTDNLSS
What is the function of this protein?
Protein phosphatase that dephosphorylates specifically tyrosine-phosphorylated peptides; especially active on dual-phosphorylated substrates containing a phosphothreonine-X-phosphotyrosine motif.
What are the official names of this protein?
Tyrosine-protein phosphatase RLPH2, Protein RHIZOBIALE-LIKE PHOSPHATASE 2.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: FPG_SHEPW
Sequence: MPELPEVEVTKQGVSPYLIDNRVTDLIIRNPSLRWPVPDIAKQIIGQTIRAVRRRAKYLLIDTDAGTTIVHLGMSGSLRILPINSPVEKHDHIDLVLASGKILRYNDPRRFGAWLWNELPEQAHPLLAKLGPEPLESAFNSSYLLSALANKKKAIKLCLMDNHIVVGVGNIYANEALFAAGIHPQAEAGKVDAERISILVAEVKQILARAIKQGGTTLKDFTNAEGKPGYFAQKLHVYGRGGDTCTHCGQLLSEIRLGQRATVFCSICQQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TO1A_HADVE
Sequence: SPTCIPSGQPCPYNENCCSQSCTFKENENGNTVKRCD
What is the function of this protein?
Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons (PubMed:17610847).  Is lethal to many insect species but not toxic to mammals (PubMed:9228949, PubMed:16779650).  May target the insect high-voltage-activated calcium channel Dmca1D.  Also inhibits acarines calcium channels.  An extremely high toxin concentration partially inhibits Cav1. 2/CACNA1C, Cav2. 1/CACNA1A and Cav2. 2/CACNA1B calcium channel of rats.  As for omega-AcTx-Hv2a, the phenotypic effect of injection of this toxin into lone star ticks (Amblyomma americanum) is curling of all eight legs into closed loops.
What are the official names of this protein?
Omega-hexatoxin-Hv1a, Omega-HXTX-Hv1a, Omega-atracotoxin-Hv1a, Omega-ACTX-Hv1, Omega-AcTx-Hv1a, Omega-atracotoxin-Hv1, Omega/kappa-atracotoxin-Hv1a, Omega/kappa-HXTX-Hv1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 08 (Shiva) family. 01 (omega toxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MOG1_YEAST
Sequence: MKIEKASHISQPVQLSTCTLIDTYPGHQGSMNNKEVELYGGAITTVVPPGFIDASTLREVPDTQEVYVNSRRDEEEFEDGLATNESIIVDLLETVDKSDLKEAWQFHVEDLTELNGTTKWEALQEDTVQQGTKFTGLVMEVANKWGKPDLAQTVVIGVALIRLTQFDTDVVISINVPLTKEEASQASNKELPARCHAVYQLLQEMVRKFHVVDTSLFA
What is the function of this protein?
Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export.
What are the official names of this protein?
Nuclear import protein MOG1, Multicopy suppressor of GSP1.
What is the protein family that this protein belongs to?
Belongs to the MOG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YJPA_BACSU
Sequence: MYTYLMLTMRTEKFNQEHVAGHYEFLDRLQAEKRLKMFGPFSDATGGAYVIEADSLEEAAEIGHADPLVASGSSELTIKEWKLKK
What are the official names of this protein?
Uncharacterized protein YjpA.
What is the protein family that this protein belongs to?
Belongs to the YciI family.