PharMolix/UniProtQA huggingface dataset:
Protein: RS10_SHESR
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTVLISPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TAM_AGRFC
Sequence: MAWSAQQYLKFEDERTRPARDLLAQVPLERVLNGYDLGCGPGNSTELLTDRYGVNVITGIDSDDDMLEKAADRLPNTNFGKADLATWKPAQKADLLYANAVFQWVPDHLAVLSQLMDQLESGGVLAVQMPDNLQEPTHIAMHETADGGPWKDAFSGGGLRRKPLPPPSDYFNALSPKSSRVDVWHTVYNHPMKDADSIVEWVKGTGLRPYLAAAGEENREAFLADYTRRIAAAYPPMADGRLLLRFPRLFVVAVKK
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_PAEAT
Sequence: MEEQDAAKPTSERHVPVLKDRCINLLAPGFEAARKRGERPVAIDATLGMGGHSEAMLQRFPDLHLVGIDRDEEALALAGARLEPFSDRTDLVHAVYDEIEDVLLDLGVPEVHGILMDLGVSSLQLDERERGFAYSYDAPLDMRMDTSRGQTAADVVNNYSEDELVRIIRKWGEEKFAGRIANRIVNARAEKPFATTGELVEQIRSVVPAAAAKSGGHPAKRTFQALRIEVNEELDVLERAVPAAVAATAMGGRIVVMSYHSLEDKIVKSVFQAGSKSSAPLGFPVELEEHKPELKTITKGTEVPTAAEIAENPRAASARLRAVERIKQRRDA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_RHIL3
Sequence: MKQSILFERVSARLKAQVGPDVYASWFARLKLHSVSKSVVRLSVPTTFLKSWINNRYLDLITGLFQAEDPEILKIEVLVRTATRHGTKALDEVVAPEPAAPTQMRRPTSAQPAGQAVQQAVSAVAAARPASFGSPLFGSPLDSRFTFDTFVEGSSNRVALAAAKTIAEAGQGAVRFNPLFIHSTVGLGKTHLLQAVANAAVQNPRSLRVVYLTAEYFMWRFATAIRDNDALTLKDSLRNIDLLIIDDMQFLQGKMIQHEFCHLLNMLLDSAKQVVVAADRAPWELESLDPRVRSRLQGGVAIEFDAPDYEMRLEILKRRLAVARLEDPSLEIPAELLQHVARNVTASGRELEGAFNQLVFRRSFEPNLSIERVDELLAHLVGSGEPRRVRIEDIQRIVARHYNVSRQELVSNRRTRVIVKPRQIAMYLSKTLTPRSFPEIGRRFGGRDHTTVLHAVRKIEELISGDTKLSHEVELLKRLINE
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_BOVIN
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4, H4.1.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CYB_PRIGL
Sequence: MAINIRKTHPLLKIMNHALVDLPAPSNISLWWNFGSLLGLCLIIQILTGLFLAMHYTADISMAFSSVVHICRDVNYGWLIRNIHANGASLFFICIYLHIARGLYYGSYLYKETWNIGVILLFLLMATAFVGYVLPWGQMSFWGATVITNLLSAFPYIGDILVQWIWGGFSVDNATLTRFFAFHFLLPFLILALTVIHLLFLHETGSNNPLGINSNADKISFHPYFSYKDLLGFFIMIFFLATLALFMPNLLGDAENFIPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSIFILMLVPLLHTSKQRSTIFRPMTQIFFWLLVANFLILTWIGGQPVEQPFMMVGQIASISYFALFLIIMPFAGWCENKILSLN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: QUEC_PHOV8
Sequence: MNKSDALVVFSGGQDSTTCLFWAKKHFRKVYALSFIYGQKHVKEVELARVIAGKAGVEFKAMDVSFIGNLGKNSLTDTTITMDEVKPADSFPNTFVPGRNLFFLSIAAVYARELGINHIVTGVSQTDFSGYPDCRDAFIKSLNVTLNLAMDEQFVLHTPLMWIDKAETWALADELGVLDLIRHETLTCYNGVQGDGCGHCPACKLRREGLEKYLEIKAEREKR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: TMM70_MOUSE
Sequence: MLLGLGGRWAAGLWPGRTRTTWCVAAALRGSGIAFWRAASLAEPERLRSGGHLALAESCGPPGRAQIPVCWEQCVRCFHTQVDKPENGRLIYTGNLARTIFGVKCFSYSTSVVSLAFLPYLLSQNNMMFGSLPLQVLFYGVMGSFTVITPTLLHLLTKGYVIRLYHEATSDTYRAVTYNVMLSETSTVFHQDDVTIPESAHIFTSFYAKTKSLLVNPALFLNPEDYNHLMGYDKPFTFDMEEVDEKKLHEGEK
What is the function of this protein?
Scaffold protein that participates in the c-ring assembly of mitochondrial ATP synthase (F(1)F(0) ATP synthase or complex V) by facilitating the membrane insertion and oligomer formation of the subunit c/ATP5MC1 through its interaction (By similarity).  Therefore, participates in the early stage of mitochondrial ATP synthase biogenesis and also protects subunit c/ATP5MC1 against intramitochondrial proteolysis (PubMed:31652072, PubMed:28173120).  In addition, binds the mitochondrial proton-transporting ATP synthase complexes I and may play a role in the stability of its membrane-bound subassemblies (By similarity).
What are the official names of this protein?
Transmembrane protein 70, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TMEM70 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Note=Mostly located within the inner cristae membrane.
Protein: SDHF2_CANDC
Sequence: MLSKSCRAISQRSFSQSSLVFANYGKPQNPPIDTEIKLKIQPIVRTGETIEVKRARLLYQSRKRGILESDLLLSRFADKYLKTMTMEELDEYDKLLDEADWDIYYWATKNYKITPLPDKWKDSKILKEIQKIANNEEKVIMRMPELNLEPESNTK
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: THIM_PEDPA
Sequence: MNLQDIAKIREVNPVVVNYANFVTPFLVANGLNAVGASPIMSDEVSEAEELVQLASAVVINAGASRKESWPLMNKLCEAANQYQKPLVLDPVAVGATQYRKALNLMLLEKYHFDVIRGNIGEIAVLAGIDWQTRGIDAGNGTGDMSAVVQACAQKFKNVVIASGEVDYISDGQQVITVHNNTKLLPAIVGSGDLLSSIVGAFSAVAENTLDAAVTASLVLSCAGERAAAQLDQQNRPGSFLSYLLDELANITPEQVQDLMKIGEA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: HBAD_STUVU
Sequence: VLTAEDKKLIQQTWGKLGGAEEEIGAEALWRMFHAYPPTKTYFPHFDLSQGSDQIRGHGKKVVAALGNAIKNLDNLSQALSELSNLHAYNLRVDPVNFKFLSQCLQVTLATRLGKEYSPEVHSAVDKFMSAVAAVLAEKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-D, Alpha-D-globin, Hemoglobin alpha-D chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SYR_CROS8
Sequence: MNIQALLSEKVSQALIAAGAPADCEPQVRQSAKAQFGDYQANGVMAIAKKLGMPPRQFAEQALAHLDLTGIAAKTEIAGPGFINIFLDPAFLAKNIEAAVASDRAGVEKVSAPQTIVVDYSAPNVAKEMHVGHVRSTIIGDASVRTLEFLGHKVIRANHVGDWGTQFGMLIAYLEKQQQENAGEMALSDLEGFYREAKKHYDEDEAFAERARSYVVKLQGGDEYCREMWRKLVDITMTQNQITYQRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTIKLSELLDEALDRARRLVAGKNPDMPADELEKLANAVGIGAVKYADLSKSRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAGVKESELTAPVVIQDDREAQLAARLLQFEETLGVVARDGTPHVMCAYLYDLAGLFSGFYEHCPILTAETDALRQSRLKLALLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_PSEFS
Sequence: MNVTALNLIPGQLSLAQLRAIYQQPVTLRLDDSATAQIEASVACVEQILAENRTAYGINTGFGLLASTRIASEDLENLQRSLVLSHAAGVGEPISDALVRLVMVLKVNSLSRGFSGIRRQVIDALIALINAEVYPHIPLKGSVGASGDLAPLAHMSLVLLGEGKARYKGEWLEATEALKVAGLTPLTLAAKEGLALLNGTQVSTAYALRGLFEGEDLFAGALACGGLTVEAVLGSRSPFDARIHAARGQRGQIDSAAAYRDLLGESSQVSQSHQNCDKVQDPYSLRCQPQVMGACLTQFRQAAEVLVVEANAVSDNPLVFAAEGDVISGGNFHAEPVAMAADNMALAIAEIGSLSERRISLMMDKHMSQLPPFLVGNGGVNSGFMIAQVTAAALASENKALAHPHSVDSLPTSANQEDHVSMAPAAGKRLWEMAENTRGILAVEWLAACQGLDLREGLKTSPKLEKARGILRDKVAFYDKDRFFAPDINAASELLATRCLNELVPANLLPSL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMS19_HUMAN
Sequence: MAAAAAVEAAAPMGALWGLVHDFVVGQQEGPADQVAADVKSGNYTVLQVVEALGSSLENPEPRTRARAIQLLSQVLLHCHTLLLEKEVVHLILFYENRLKDHHLVIPSVLQGLKALSLCVALPPGLAVSVLKAIFQEVHVQSLPQVDRHTVYNIITNFMRTREEELKSLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISRDYSLGPFVEELFEVTSCYFPIDFTPPPNDPHGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSRSVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACDSVTSNVLPLLLEQFHKHSQSSQRRTILEMLLGFLKLQQKWSYEDKDQRPLNGFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGAQPDLLSYEDLELAVGHLYRLSFLKEDSQSCRVAALEASGTLAALYPVAFSSHLVPKLAEELRVGESNLTNGDEPTQCSRHLCCLQALSAVSTHPSIVKETLPLLLQHLWQVNRGNMVAQSSDVIAVCQSLRQMAEKCQQDPESCWYFHQTAIPCLLALAVQASMPEKEPSVLRKVLLEDEVLAAMVSVIGTATTHLSPELAAQSVTHIVPLFLDGNVSFLPENSFPSRFQPFQDGSSGQRRLIALLMAFVCSLPRNVEIPQLNQLMRELLELSCCHSCPFSSTAAAKCFAGLLNKHPAGQQLDEFLQLAVDKVEAGLGSGPCRSQAFTLLLWVTKALVLRYHPLSSCLTARLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHAEVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDCVVQLSTLSCLQPLLLEAPQVMSLHVDTLVTKFLNLSSSPSMAVRIAALQCMHALTRLPTPVLLPYKPQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS
What is the function of this protein?
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity (PubMed:29848660).  In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER), homologous recombination-mediated double-strand break DNA repair, DNA replication and RNA polymerase II (POL II) transcription (PubMed:22678362, PubMed:22678361, PubMed:29225034, PubMed:23585563).  As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur (Fe-S) cluster assembly into ERCC2/XPD (PubMed:20797633).  Together with CIAO2, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization of KIF4A to mitotic machinery components to promote the progression of mitosis (PubMed:29848660).  Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery (PubMed:11279242).
What are the official names of this protein?
MMS19 nucleotide excision repair protein homolog, hMMS19, MET18 homolog, MMS19-like protein.
What is the protein family that this protein belongs to?
Belongs to the MET18/MMS19 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In mitosis, enriched on centrosomes during prophase, localizes to the spindle during metaphase and surrounds compacted spindle midzone microtubules during telophase.
Protein: EFTS_PSYWF
Sequence: MSKISAKLVKELRDRTGLGMMECKKALEETNGDVEQAIDNLRKSGQAKAAKKAGNIAADGAIVIAQEGNKAILLEVNCQTDFVAKDDNFTEFANKVAELALANNTTDVAAISELDYGNGQSVEEARVALVQKIGENIQVRRAKIIEGDNLASYRHGLRIGVVVSSEGGQEDSGKNLAMHIAAFNPVAVNDTDVPADILAREKDIAEAKARESGKPDNIIEKMIEGGLRKYLDEVVLVRQAYVMDNEKKVGDVLKADGVTVKDFVRFEVGEGIEKKQEDFAAEVAAAQAAAAQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BORC5_CHICK
Sequence: MAGVNGSHASPSPAKQRAKMDDIVVVAPGTQSSRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNTKLEKLDPHQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLYSFMQERQKKYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPESEQLEPFSMKPDREIKS
What is the function of this protein?
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery.  Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor.
What are the official names of this protein?
BLOC-1-related complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the BORCS5 family.
What are the subcellular locations of this protein?
Lysosome membrane; Lipid-anchor; Cytoplasmic side.
Protein: AMPA_BACCR
Sequence: MFQVQKELAGHEAVIVALFEEEKMSSFVQELDKAFEGQLQVLLEEKELSTKKKAISKVHSLGKTNVKRYYFVGLGKKESYTTETLRAALGKAFKTLQAAKVQDAAILLDSFVTEKLDAIDVAHIAAEVQGLGTYELQTYKSDKKDRVELEKFMAITSEDAQEIEAALTVGYVHGRATNSARTLVNMPPNVLTATKLAEYAVELAEKYDMDYKVLEKEEMEDLGMGALLAVNQGSVEPPKMIALIYKGKEEWKDVIGFVGKGITYDTGGYSLKPREGMVGMKGDMGGAAAVLGAMEIIGELRPEQNVIAVIPSTDNVVSGTAFKPDDVITSMSGKTIEVLNTDAEGRLALADGITYAKKLGANYLVDVATLTGGVIVALGNYTTGAMTNNEELFEQVLEASMETDEPIWQLPIFDRDKERVRNSKFADLNNSPGREGHAVMAGTFLGEFAEDTPWVHLDIAGTSETKGAHDLGPAGATGAMVRTLATLVERFGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSGA_STRR6
Sequence: MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVDFSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHKGIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGVGKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVSRAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEIENRRETYKKVSKKIPK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA3_ORYSJ
Sequence: MGVYTFVCRSSGDEWTAKQLKGELEASAATPYELQRRLVAAASAADSAAGVQSSFSMVSPSSAVFQVIIGAVGGGAAIGGGAAAGAASGGAAAEAPKAEEKKEEEKEESEDDLGFSLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P3, P1/P2-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: RXRB_CANLF
Sequence: MSWAARPPFLPQRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAAAAGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGAPPPSPPGLPLPPSSAPTLGGSGAPPPPPMPPPQLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGEGAGGAPEEMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA
What is the function of this protein?
Receptor for retinoic acid.  Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes.  The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).
What are the official names of this protein?
Retinoic acid receptor RXR-beta, Nuclear receptor subfamily 2 group B member 2, Retinoid X receptor beta.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ENGB_MYCAP
Sequence: MWKFVKSALKKETWVKCEDCIQICFWGRSNVGKSSLLNALVNQKISYVSKQPGRTQFINYFQEENRFIVDLPGYGYAQLSKEKIEEMNYWISAFLKDDKCTKVMFLLIDSRTGITKIDLEKLAFLKAINLPIHLIYTKIDKLNQKEKSALVKKHNEYLDSNLLNESTNSFLVSSTNKIGLDDLVLFIEENIFKK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: TRUB_NEIMA
Sequence: MTNKPAKRPVNGVLLLDKPEGLSSNTALQKTRHLFRAEKAGHTGVLDPLATGLLPVCFGEATKFAQYLINADKAYTATLKLGEASSTGDAEGEIVATARADISLAEFQTACQALTGNIRQVPPMFSALKHEGKPLYEYARKGIVIERKARDITVYAIDIAEFDAPKAVIDVRCSKGTYIRTLSEDIAKHIGTFAHLTALRRTETAGFTIAQSHTLEALANLDETERDSLLLPCDVLVAHFPQTVLNDYAVHMLRCGQRPRFEEDLPSDTPVRVYTENGRFVGLAEYQKEICRLKALRLMNTAASAA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: PYRC_LACDB
Sequence: MQTVIKNGTVYQNGRLIHADVLIEDQKIKAIGTDLTGDKVIDATGKLVSPGLVDVHVHYRDPGQTYKEDIETGSKAAAHGGFTTVGAMPNVTPVPDTPDLMKKMVQENKQKGIVHIFQYGPITKNETTDELPDYAALKKAGAFALSNDGHGVQTAQTMYLAMQEAKKNDLIVAAHAQDDSLFNHGIVNEGEKAKELNLPPVTELAETTQIARDLLLAEKTGVHYHICHVSTKTSVELVRIAKACGINVTCEAAPHHLLLTEDDIPKDNGYYKMNPPLRSKEDQVALLVGLLDGTIDLIATDHAPHAKQEKQGGMQNAAFGITGSETAFSTLYTKFVKEDKVFTLEQLLSWLSDQPAKVFGLKKAGVLEPGCPADVAIFDLEHETELKEKNYQSKGINTPFTGQKIYGATVMTMVDGEVVYQRGEK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: PANE_BACSU
Sequence: MKIGIIGGGSVGLLCAYYLSLYHDVTVVTRRQEQAAAIQSEGIRLYKGGEEFRADCSADTSINSDFDLLVVTVKQHQLQSVFSSLERIGKTNILFLQNGMGHIHDLKDWHVGHSIYVGIVEHGAVRKSDTAVDHTGLGAIKWSAFDDAEPDRLNILFQHNHSDFPIYYETDWYRLLTGKLIVNACINPLTALLQVKNGELLTTPAYLAFMKLVFQEACRILKLENEEKAWERVQAVCGQTKENRSSMLVDVIGGRQTEADAIIGYLLKEASLQGLDAVHLEFLYGSIKALERNTNKVF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_MYCTU
Sequence: MANFTAADVKRLRELTGAGMLACKNALAETDGDFDKAVEALRIKGAKDVGKRAERATAEGLVAAKDGALIELNCETDFVAKNAEFQTLADQVVAAAAAAKPADVDALKGASIGDKTVEQAIAELSAKIGEKLELRRVAIFDGTVEAYLHRRSADLPPAVGVLVEYRGDDAAAAHAVALQIAALRARYLSRDDVPEDIVASERRIAEETARAEGKPEQALPKIVEGRLNGFFKDAVLLEQASVSDNKKTVKALLDVAGVTVTRFVRFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DRS1_SCLS1
Sequence: MAPKRNRDDDFVLTLSDNEGEDLTNVIEEELPLDPSSNKKRKRNDDIASTKKSKKSKKKSEDEDVEEEEIWGIKDADDGAMDSDFEFALEADGKGGADLEEFEGWGFDGAKKGLNGGDKKAVDIDEIIARRREKKKATGKKGEAEDEVIAEKEDVVASDEEQDAPEEMDFEDEDDEFMAEDGFGMGAGSAEESGAEEDSEASDNEGAEDDDSDNDSVASPAPHPDDAASEASDDDEDIDEDPEEAAKREAFFAPEEKPVKGAKPELNSTFQSMSLSRPILRGLATVGFTQPTPIQSKTIPVALLGKDVVGGAVTGSGKTAAFIVPVLERLLYRPKKVPTSRVAILMPTRELAIQCHAVATKLASHTDIKFCLAVGGLSLKVQEAELRLRPDVIIATPGRFIDHMRNSPSFTVDTLEILVLDEADRMLEAGFADELNEILTTIPKSRQTMLFSATMSSSVDNLIRVGLNRPVRLLVDSQKSTAGTLTQEFIRLRPGREGKRMGYLLYLCANVYTDRVIVFFRQKKEAHRARIIFGLSGLKATELHGSMSQEQRIKSVEAFRDGKASFLLATDLASRGLDIKGVDTVINYEAPQSHDIYLHRVGRTARAGRSGRACTIAAEPDRKVVKAAVKASRTQGAKVVSRVIEASEADSWSEKVDEMADEIEEILKEEKEDKILAQAEMEVRKGQNFMDHEAEIKGRPKRTWFESEKEKLAAKKLGMEELNGVVGGKKKGKLSNKDKKKLDDKGERLEGRVWKKGRQERDGKGVLAKEKGKKKVKGGKPAGLGKKKAMKPMRTGGAKRR
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase drs1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.