PharMolix/UniProtQA huggingface dataset:
Protein: FRDC_PROVU
Sequence: MTTKRKPYVRGMQPNWWTKLGFYRFYITREGTCLPQLWFSLVVLFGVFALKNGPESWAGFVGFLSNPILMLINIVTLIATVFHTATWFKLAPKAVNIVVKDEKLPQEPIVRGLWGLTIVVTVVILAVALIV
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LCPS_ARTGP
Sequence: MGLDYLMVHVKYNLPPALLLTILYKPFFTRLEVHKIVLLCTIAVVWTIPWDSYLIRTRIWSYPADSVLGQTLFQIPLEEVFFFIIQTYNTSLLYIIFNKRLVLPSYLSGPTKPLAQGLFGPITHRTQRDLGTLFFTGILILGISFIYIGGEYMYLGLILSWVSPILVMQWVLMYRFLLALPPASVWVPIALPTLYLWVVDTLALRRGTWVIESGTKVDIQLWEGLEIEEALFFLVTNVMVVFGIAAMHNAAALFEYKAFISTTAMGDTPSIYQLITLFLTSSRLYDTNVLQEMSQAVTLLKQKSQSMYLGSAMFEGQLRLDLIALYSFCRKADDLIDDAPDRETAKYWIEQCEKALELRFKLKETALDDTEAYQLLTKSIPQPLHAAAHLLPASRLPKEPLSCLLQGFEIDLKFDFEKGSFPIATEHDLEVYAYHVAGTVASLLLELVFRHHPVSISEAERLRVISAGEVMGRALQYTNIARDITRDAEIGRVYIPSSWLAEEGLTPSMVISHPRNSKLIPLRRRILEKADKCYCETQEAISKLPSNVQGPVRATVTAYMEIGQVIRENETKIWNGKLKVSRWRRFKRAWLAML
What is the function of this protein?
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
What are the official names of this protein?
Bifunctional lycopene cyclase/phytoene synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PTH_NOVAD
Sequence: MQLWVGLGNPGPQYALHRHNVGFMALDTIAEVHNFGPVQKKFQGWLQEGRIGTEKVLLLKPATFMNESGRSVGEAMRFYKLGMDALVVFHDELDLAPFKVKVKQGGGTAGHNGLRSIDKHLGPDFLRVRLGIGHPGHKDRVTGHVLGNFAKSEQDDLVDMLGAIASEAALLAKGDNVLFMNNIALRQQTAG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_BACAA
Sequence: MNKGQRHIKIREIIANKEIETQDELVDILRNEGFNVTQATVSRDIKELHLVKVPLHDGRYKYSLPADQRFNPLQKLKRNLVDSFVKLDTAGHMLVLKTLPGNAHSLGALIDHLEWDEIIGTICGDDTCLIICRTPEDTGVVSDRFLNML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMB1_HYDVU
Sequence: MNGRTQNLWFSTFRLVIVYALFFAKLCFGQEECLRGGCYPATGDLLVGRENRITATSTCGLKERTTGVCNNCLHNTKGTNCQLCKDGYYGNALLGTENVCQRCQCPGGSSGNQFSNTCELRDVGKVFCTNCSEGFTGTQCEKCDNGYYGNPLIQGGTCKKCLCNGNINSAS
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
What are the official names of this protein?
Laminin subunit beta-1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: PVK3_PILDU
Sequence: GSSGMIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-3, PilDu-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_PSEE4
Sequence: MPRRRVAAKREILDDPKYGSQILAKFMNHVMESGKKAVAERIVYGALDTVKARKNSDPLEIFEKALDAIAPLVEVKSRRVGGATYQVPVEVRPSRRNALAMRWLVDYARKRGEKSMALRLAGELLDAAEGKGAAVKKREDVHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GALP_ECOL6
Sequence: MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIADEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAAPNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLSDTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTSAEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPKIFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVLGTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTATNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERNLMKGRKLREIGAHD
What is the function of this protein?
Uptake of galactose across the boundary membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
Galactose-proton symporter, Galactose transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GNA14_MOUSE
Sequence: MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYMCEQNKENAQIIREVEVDKVTALSRDQVAAIKQLWLDPGIQECYDRRREYQLSDSAKYYLTDIERIAMPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFRTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVKAARDFILKLYQDQNPDKEKVIYSHFTCATDTENIRFVFAAVKDTILQLNLREFNLV
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit alpha-14, G alpha-14, G-protein subunit alpha-14.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: PANB_PROM3
Sequence: MRPSELTQLKQDGRAISILTAWDGLSAALVEAAGADVVLVGDSLAMVALCHATTLPVTVEQMLHHTQAVGRGFTRPLPQQPLVVCDLPFLSYQCGEDKAVAAAGSLLKHSCAAAVKLEGAEPEVLAVIERLVRMGIPVMGHLGLTPQAVHRLGYRRQAEDPRSQAQMLQQAKQLEQAGCFALVVEHVPSSIARCLSQQLTIPVIGIGAGEDCDGQVRVTADLLGLTPSQPPFSPPLIQGRQLCVEALQGWVKQLHQQAETATTTTSQPEPDC
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INCD_CHLTR
Sequence: MTKVYANSIQQERVVDRIALLERCLDPSNSLPTAKRLVAVAVATILAVALLVVAGLLFSGVLCSPVSVLAASLFFGVGAFLLGGALVGGVLTTEAVTRERLHRSQTLMWNNLCCKTAEVEQKISTASANAKSNDKTRKLGE
What is the function of this protein?
Inclusion membrane protein probably involved in early modification events of the chlamydial inclusion.
What are the official names of this protein?
Inclusion membrane protein D.
What are the subcellular locations of this protein?
Secreted. Host vacuole, host pathogen-containing vacuole, host pathogen-containing vacuole membrane; Multi-pass membrane protein. Note=Secreted, probably by a type III secretion system (By similarity). Localized in the inclusion membrane (By similarity).
Protein: WHITE_ANOAL
Sequence: MTINTDDQYADGESKTTISSNRRYSTSSFQDQSMEDDGINATLTNDKATLIQVWRPKSYGSVKGQIPAQDRLTYTWREIDVFGQAAIDGKSREPLCSRLRHCFTRQRLVKDFNPRKHLLKNVTGVARSGELLAVMGSSGAGKTTLLNELAFRSPPGVKISPNAIRTLNGVPVTAEQMRARCAYVQQDDLFIPSLTTKEHLMFQAMLRMGRDVPATPIKMHRVDEVLQELSLVKCADTIIGVAGRVKGLSGGERKRTAFRSETLTDPHLLLCDEPTSSLDSFMAQSVLQVLKGMAMKGKTIILTIHQPSSELYCLFDRILLVAEGVAFLGSPYQSADFFSQLGIPCPPNYNPADFYVQMLAIAPNKETECRETIKKICDSFAVSPIARDIIETASQVNGDGGIELTRTKHTTDPYFLQPMEGVDSTGYRASWWTQFYCILWRSWLSVLKDPMLVKVRLLQTAMVASLIGSIYFGQVLDQDGVMNINGSLFLFLTNMTFQNVFAVINVFSAELPVFLREKRSRLYRVDTYFLGKTIAELPLFIAVPFVFTSITYPMIGLKAAISHYLTTLFIVTLVANVSTSFGYLISCASSSISMALSVGPPVVIPFLIFGGFFLNSASVPAYFKYLSYLSWFRYANEALLINQWADHRDGEIGCTRANVTCPASGEIILETFNFRVEDFALDIGCLFALIVLFRLGALFCLWLRSRSKE
What is the function of this protein?
May be part of a membrane-spanning permease system necessary for the transport of pigment precursors into pigment cells responsible for eye color.
What are the official names of this protein?
Protein white.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VKT_VIPBN
Sequence: MSSGGLLLLLGLLTLWAELTPVSSRDRPKFCYLPAEPGECNAYMPSFYYDSASNKCKKFIYGGCRGNANNFKTRDECHHTCVASGKGIQPRIGSN
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor ki-VN.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: SC1_SCHCO
Sequence: MRFSLAILALPVLAAATAVPRGGASKCNSGPVQCCNTLVDTKDKHQTNIVGALLGLDLGSLTGLAGVNCSPVSVIGVGGNSCSTQTVCCEGTQFNGLVNVGCTPINVGL
What is the function of this protein?
Contributes to surface hydrophobicity, which is important for processes such as association of hyphae in reproductive structures, dispersal of aerial spores and adhesion of pathogens to host structures.
What are the official names of this protein?
Fruiting body protein SC1, Hydrophobin SC1.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted. Note=Secreted in aqueous environment.
Protein: RL28_NOVAD
Sequence: MSRICELTGKGRQVGHNVSHANNKTKRLFLPNLQNVTLLSEKLDRSFKFRVSTHGLRSVEHNGGLDNWLLKQSDTKLSARALKVKRELVKASAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NCAP_SENDE
Sequence: MAGLLSTFDTFSSRRSESINKSGGGAVIPGQRSTVSVFVLGPSVTDDADKLFIATTFLAHSLDTDKQHSQRGGFLVSLLAMAYSSPELYLTTNGVNADVKYVIYNIEKDPKRTKTDGFIVKTRDMEYERTTEWLFGPMVNKSPLFQGQRDAADPDTLLQTYGYPACLGAIIVQVWIVLVKAITSSAGLRKGFFNRLEAFRQDGTVKGALVFTGETVEGIGSVMRSQQSLVSLMVETLVTMNTARSDLTTLEKNIQIVGNYIRDAGLASFMNTIKYGVETKMAALTLSNLRPDINKLRSLIDTYLSKGPRAPFICILKDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGRTYLDMEMFLLGQAVAKDAESKISSALEDELGVTDTAKERLRHHLANLSGGDGAYHKPTGGGAIEVALDNADIDLETEAHADQDARGWGGESGERWARQVSGGHFVTLHGAERLEEETNDEDVSDIERRIAMRLAERRQGILQPMEMKAAITVWITTKMTMPQQ
What is the function of this protein?
Encapsidates the genome in a ratio of one N per six ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure with 13. 07 N per turn.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA.  In contrast, when associated with RNA, it is termed N.  During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: RL4_GLAP5
Sequence: MELQVVGATALSVSETTFGREFNEALIHQVVVAYAAGARQGTRAQKTRAEVSGSGKKPWRQKGTGRARSGDIKSPIWRSGGVTFAAKPQDHSQKVNKKMYRGAIKSILSELVRQDRLVVVDKFEIDAPKTKVLVQKLKDMALTDALIITASLDENLFLAARNLYKVDVRDVQGIDPVSLIAFDKVVITVDAVKQIEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: CNTFR_CANLF
Sequence: MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDLALDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTTHTITDAYAGKEYIIQVAAKDYEIGTWSDWSVAAHATPWTEEPRHLTTEAQAPETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLIHVPVTLALAAAAATANSLLI
What is the function of this protein?
Binds to CNTF.  The alpha subunit provides the receptor specificity (By similarity).
What are the official names of this protein?
Ciliary neurotrophic factor receptor subunit alpha, CNTF receptor subunit alpha, CNTFR-alpha.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MIAA_LACGA
Sequence: MFMQKIIVLIGPTGIGKTELALKLAPKINAEIISGDSMQIYQEVSIGTAKPTAEELRQVKHYLVNQRSIFDEYSVKDFVAEGKKAVNQIAAKGSIPLVVGGTGFYINALVNKLQLGEPGDYQTSVDSKWEKYLKDNGAEKLWQLLDEKDPVAAKKIAPQNSRRTLRALTVISRTGKLFSQQQAQISPRYDALIIGLNSNREEVYQRINKRVDKMMNAGLLKEAKFVYDNRAREHQAIQAIGYKEFFPYFSGEKTLDECVNKLKQASRKYAKRQLTYFKHQLSVVWLDPLQDKEVSERALNEIKSFLNK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: HXC12_HUMAN
Sequence: MGEHNLLNPGFVGPLVNIHTGDTFYFPNFRASGAQLPGLPSLSYPRRDNVCSLSWPSAEPCNGYPQPYLGSPVSLNPPFGRTCELARVEDGKGYYREPCAEGGGGGLKREERGRDPGAGPGAALLPLEPSGPPALGFKYDYAAGGGGGDGGGGAGPPHDPPSCQSLESDSSSSLLNEGNKGAGAGDPGSLVSPLNPGGGLSASGAPWYPINSRSRKKRKPYSKLQLAELEGEFLVNEFITRQRRRELSDRLNLSDQQVKIWFQNRRMKKKRLLLREQALSFF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C12, Homeobox protein Hox-3F.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXJ_MAGMM
Sequence: MILLGVNIDHIATLRQARGERYPDPVDAAFAAERAGADSITVHLREDRRHIQDRDVVLLQQTCQTKINLEMAASEPMLTLAERWKPQDCCLVPEKRHELTTEGGLDVVGNRHRLADAVARLHDAGIRVSLFVDPDLEQISAAGAIGATVVEMHTGRYANAATQAQRNLELEQLYRAAHQASLNGLTVHAGHGLTYHNVQPIARLPDLKELNIGHAIIARAVMVGMESAVKEMKRLMREAVKTP
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAP2_PUCGT
Sequence: MTGHAPLVGVIGGSGLYKLEGIEPVESLNIDTPWGRPSSPITLFKLPSGPVVAFLARHGVSHQFTPSEVPSRANIAALKKIGCQVIIAFSAVGSLREEIKPRDIVVPSQIIDRTKSAHAMFGEPFDTELTGLVTKSIKEAVTGFEMNDRIGVHAEKVAICMEGPAFSTRAESNMYRMFGGDIINMSVLPEAKLAREAELSYALIAQITDYDAWRESEEPVTVAEVMATIAANVSVSNRLTLTILDEVHNAVAKGQLKTCKGTMEYSVMTKKEMISEESKKTLSFILPYFS
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase 2, 5'-methylthioadenosine phosphorylase 2, MTA phosphorylase 2, MTAP 2, MTAPase 2.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RSMA_LARHH
Sequence: MSRHIPKKRFGQNFLQDAFIIHSIVAAVDARPGDVVVEIGPGLGALTRPLLRALPQLHVVEIDRDIIARLAAEFPPERLVIHEGDALAFDFGALAHEQPLKLVGNLPYNISTPLLFHLATYADRVTDMHFMLQKEVVDRMVADPGCADYGRLTVMLQYRFAMERLIDVPPESFDPPPKVDSAVVRMIPHAELPWPADDEENLSALVAQAFAQRRKTLRNNLRGWLDDDDFAALGIDPQRRPETLTLREFVLLSNRHGEKGRQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UFSP2_HUMAN
Sequence: MVISESMDILFRIRGGLDLAFQLATPNEIFLKKALKHVLSDLSTKLSSNALVFRICHSSVYIWPSSDINTIPGELTDASACKNILRFIQFEPEEDIKRKFMRKKDKKLSDMHQIVNIDLMLEMSTSLAAVTPIIERESGGHHYVNMTLPVDAVISVAPEETWGKVRKLLVDAIHNQLTDMEKCILKYMKGTSIVVPEPLHFLLPGKKNLVTISYPSGIPDGQLQAYRKELHDLFNLPHDRPYFKRSNAYHFPDEPYKDGYIRNPHTYLNPPNMETGMIYVVQGIYGYHHYMQDRIDDNGWGCAYRSLQTICSWFKHQGYTERSIPTHREIQQALVDAGDKPATFVGSRQWIGSIEVQLVLNQLIGITSKILFVSQGSEIASQGRELANHFQSEGTPVMIGGGVLAHTILGVAWNEITGQIKFLILDPHYTGAEDLQVILEKGWCGWKGPDFWNKDAYYNLCLPQRPNMI
What is the function of this protein?
Thiol-dependent isopeptidase that recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins (PubMed:25219498, PubMed:32160526).  Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins (PubMed:25219498).  Through TRIP4 deufmylation may regulate intracellular nuclear receptors transactivation and thereby regulate cell proliferation and differentiation (PubMed:25219498).
What are the official names of this protein?
Ufm1-specific protease 2, UfSP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Nucleus.
Protein: MAG5_ARATH
Sequence: MASTADFLLDDQTDEDFFDKLVDDSYTPTASSSAKELKFDDGSDSDDAKAFANLSVVDDVLGDGDVALNEAGLGNDVANEGTSGSVGKEEPSSSIAPEAVQFVNSDANRLRDVDVVRSEVDDMALTETGKESNIVDGSGSPGVKEVDWGSFYADSSVNDGGGFGSYSDFFTELDATAGNVQGQAEVAVATGGNLVANDTINTSVGLDNSAGFEQHQGQVQHDSGSGQYVDNSQSWENLYPGWKYDASTGQWYQVDGQDATVNSQESYINSTGNWESVAADNSDVAYLKQSTTSAMAGTAESVSTWNQVSQVGNGYPEHMVFDAQYPGWYYDTIAQEWRSLDSYNQASQTTVTGQAHDQQVQNGHARTTTYHNNSQSSVYDVNNKNQTFKAQDFAIQGQHGSWDESYYANNQQAGNTWQPVNVGKAEPAVTSDSLSRFGGNQQVNNLYSTESVAEQFKPNTIGAQSFIPQHMNVASATQNGPLSFSNDLYNRQQSVDHAQKSFQNNQLFSPSVGRSSDRRPPHALVSFGFGGKLIVMKDNNGSLQNTSFGSQGIGGSSITVLNLAEVISGSASYSSPGEDSLSYFRCLHQQSLPGPLVGGNVGSKELHKWIDERLLHCESSNMDFSRGKLLKMLLSLLRISCQYYGKLRSPFGSDASQKETDTPEAAVAKLFAFAKKDGIQNGYAPISQCLQHLPPESQMQVTASEVQNLLASGRKMEALQCAQEGHLWGPALVIAAQLGDQFYVDTVKQMALRQLIPGSPLRTLCLLVAGQPAEVCPTGSSSSMLDNWEENLGIITANRTTDDDLVIIHLGDSMWKERGEIIAAHICYLIADKNFDPYSESARLCLVGADHWKCPRTYASPDAIQRTELYEYSKTLGNSQYILLPFQPYKIIYAHMLAEVGKLSTAQKYCQAVIRCLKTSRSSEVEMWKQFASSLEERIRSHQEGGNLAPAKLVGKLLNSLWGMPPPAPHSTTGNPQVNEYQHQQQEAAKLSYSQSANTMSSLMPPASIEPVHEWGGNGRTMAAHSRSVSEPDFSRTPIQDQTDSSKDKAPDGVTQVKSTRKVPSSRFSRFGIGILKNTVGKVFPSRSSNEAKLGNENQFYYDDNLKRWVERGVEPPAEEAALPPPPTSVPFRSNSLGHENKSEIKNEMSPSSGSWSSGSPTPSENSPGIPPVSQGSNQFSARGRMGVRARYVDTYNQGSSSMYQSPPVQSSKPPIPAKAKFFVPAAPASFANDQVMESVSAETRQENSGDEAVVGSAGAPGPSQASFQSPTPSPIAMQRFPSVDNIRRSGSGTSLNGDLPQSVSRRTASWSGSVNSSSFMSPTSASTFRPSPLNSSSSSLGEELQEVEL
What is the function of this protein?
Required for efficient protein export from the endoplasmic reticulum (ER) to the Golgi by regulating COPII coat dynamics at the ER.  Functions as a scaffold and regulator of COPII coat assembly at ER exit sites.
What are the official names of this protein?
Protein transport protein SEC16A homolog, Protein MAIGO 5.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack. Endoplasmic reticulum. Note=Localizes at Golgi-associated cup- shaped endoplasmic reticulum exit sites.
Protein: TAL_STRP1
Sequence: MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIKEICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQAEIIAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN879_HUMAN
Sequence: MARRLLPAHVQESVTFRDVAVFFSQDEWLHLDSAQRALYREVMLENYSILVSLGILFSKPKVISQLEQGEDPWMVESGVPQGAHLGWESLFGTIVSKEENQEVMKKLIIDGTFDFKLEKTYINEDKLEKQQGKKNRLFSKVLVTIKKVYMKERSFKGVEFGKNLGLKSSLIRKPRIVSRGRRPRSQQYSVLFKQLGVNTVRKCYKCNICGKIFLHSSSLSKHQRIHTGEKLYKCKECRKAFSQSSSLTQHLRVHTGEKPYICSECGKAFSFTTSLIGHQRMHTGERPYKCKECGKTFKGSSSLNNHQRIHTGEKPYKCNECGRAFSQCSSLIQHHRIHTGEKPYECTQCGKAFTSISRLSRHHRIHTGEKPFHCNECGKVFSYHSALIIHQRIHTGEKPYACKECGKAFSQSSALIQHQRIHTGEKPYKCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTHRKIHTGEKPYKCNDCEKAFNQSSALIQHQRIHTGEKPYNCKVCGKAFRQSSSLMTHMRIHTGEKPYKCKECGKAFSQSSSLTNHQRTHN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 879.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.