PharMolix/UniProtQA huggingface dataset:
Protein: MSHR_SAGGE
Sequence: MPMQGAQRKLLGSLNSTPTATSNLGLAANHTGAPCLEVSIPDGLFLSLGLVSLVENVLVVAAIAKNRNLHSSMYCFICCLALSDLLVSGSNMLETAVILLLETGALATRTSVVQQLHNTINVLTCSSMLCSLCFLGAIAVDRYISIFYALRYHSIMTLPRAQRAIAAIWVASVLSSTLFITYYDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAHGIIRLHKRQTPAHQAFGLRGAATLTILLGIFFLCWGPFFLHLTLVVFCPQHLTCSCIFKNFKVFLTLIICNTIIDPLIYAFRSQELRRTLKEVLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_CHRSD
Sequence: MRASQLLISTLKETPADADIVSHQLMLRAGMIRRLSSGLYTWLPLGLRTLRKVENIVREEMNRAGAQEVLMPSIQPAELWQESGRWDQYGNLLLRIRDRHERDFCYGPTHEEVITDLVRNEIRSYKQLPSNFYQIQTKFRDETRPRFGVMRAREFIMKDAYSFDIDQAGLQRSYDAMYDAYMRIFTRLGLDFRAVEADNGDIGGSGSHEFQVLADSGEDAVIFSTGSDYAANIEKAEALPAPLGETPERPAPQEELRLVDTPNARTIATLVEQHGLPIEKTIKTLMVHGSEGGLVALLVRGDHELNEVKAENLPEVAAPLTMASEEEIRAAVGAGPGSLGPVNLDMPLIIDRSVALMSDFGAGANIDGQHYFGINWERDVALPKVADLRNVVEGDPSPDGKGTLSIARGIEVGHVFQLGTKYSTAMNATVLDDNGQAVPLLMGCYGIGVTRVVAAAIEQNHDAGGIIWPDAIAPFEIALVPMNAHKSERVREYADTLYQQLSDAGFDVLIDDRDLRPGVKFADQELIGIPHRVVIGDRGLDNDELEYKGRRDSDVTMVPTEGLLSFLRERITK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_BACC2
Sequence: MIYYVIALFVIAIDQISKWLIVKNMELGTSIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVVFIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKAKE
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FIEF_ECOSE
Sequence: MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGIQHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMMNGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVIIHQDPCSVVPREGKRSMLS
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RF1_CHLAD
Sequence: MFDKLEAVAQRYDELTQLMAQPEVATNVTLLQQYAREQRELEDIVTTYREYQAAQRAIAEAEAMLDENDPELRALAQEELDTQRKRLATLEEQLKVLLLPRDPNDSKDVIMEIRQGEGGDEAALFAADLFRMYTRFAESRGWKVEVDSLTENGIGGIKEVIFQIHGEGAYSQLKYEGGVHRVQRVPATEARGRIHTSTATVAVLPEVEETEIEIKPEDLRIDVFRSAGHGGQGVNTTDSAVRIVYKPGTPEEIVVTCQDGRSQIQNRERAMTVLRARLYAREQEKRQREIGASRLAQVGSGERAEKIRTYNFPQDRITDHRIGQNFSNLPAVLDGELDKIIEALIVYDTAERLRASGISNN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCAM5_MOUSE
Sequence: MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM
What is the function of this protein?
Required for the calcium-dependent exocytosis of signal sequence-containing cytokines such as CCL5.  Probably acts in cooperation with the SNARE machinery (By similarity).
What are the official names of this protein?
Secretory carrier-associated membrane protein 5, Secretory carrier membrane protein 5.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family. SCAMP5 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Mainly localizes in Golgi apparatus membrane. Upon calcium-triggered exocytosis, it translocates to the cell membrane. Highly enriched in synaptic vesicles (By similarity).
Protein: RPOZ_PERMH
Sequence: MNKRPLIEQALKRVNNRYELVHAAAKLAKDLYETGAESYVTEEGIPLKKTVISINEIAKGRAVILRKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: CALC_CALS5
Sequence: CISARYPCSNSKDCCSGSCGIFWTCYLRKDPCSKECLAP
What is the function of this protein?
Causes paralysis to insect larvae (H. virescens).  This toxin is active only on insects.
What are the official names of this protein?
U1-nemetoxin-Csp1c, U1-NETX-Csp1a, Toxic peptide C.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 13 (insecticidal toxin ABC) family. 02 (Calisoga) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOA_ANADF
Sequence: MLTPLQTYFPIAVALLVAVGLAAVMLALANVLGPRRPSEVKSTPFECGSLPVSPARERFSVKFYVVALLFIVFDIEAIFLYPWAVLLLPSDGYPGLGWAGYISMGIFVATLVAGLVYVWKKGVLDWAD
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: STKLH_ARATH
Sequence: MVTPKQIDFSSCGGGDNSDDTLSHRESPRNPSSKRAAASFAAEAGEETMKKKKKKKKKNLGPPLIVRIWNEEDELSILKGLVDYRAKTGFNPKIDWDAFYSFLGSSIVAKFSKEQVLSKIRKLKRRFHVHWEKISEGNDPKFTRSSDSEAFGFSSMIWGQGEFGNDDGMDKEMVKEHDVNGNGAAENGTARIAQENESGEEMLKEHEETLNENGAEEIRDNDETARKAQQLESESEEEMLKEHEEPFNENGAENIRDNNGTTQIAQQSESESEEMLKEHEEVANTELVNENGAAKTTENGTTGGKERHDDDDDDELCAVQDAFEAVMSQGLSGYQKKLQLEKLMNLGTGKRRELSDEWKALCVEERRLNIKKLRFSAKLAEAANDS
What is the function of this protein?
Probable transcription factor.  May play redundant roles with GEBP and GPL2 in cytokinin responses by regulating the transcript levels of type-A ARR response genes (PubMed:18162594).  Involved in stress responses (PubMed:21875893).  Plays a repressive role in cell expansion by counteracting the positive role of CPR5 in this process, but does not regulate cell proliferation or endoreduplication (PubMed:21875893).
What are the official names of this protein?
GLABROUS1 enhancer-binding protein-like 1, Protein GPL1, Storekeeper-like protein At2g25650.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MATK_ADADI
Sequence: MEEFQVYLELNRSRRHDFLYPLIFREYIYALAHDHGLNKSMIFLENQGYVNKFSSLIVKRLIIRMDQQNHLIISANDSNQNPFFGHNNNLYSQMISAGFAVIVEIPFSLRLVSYSQGEEVAKSHNLQSIHSIFPFLEDKFSHLNYVLDVLIPHPIHLEILVQALRYWVKDASSLHLLRFSLYEYCNLKSFITPKKSISIFNPRLFFFLYNSHACEYESIFLFLRNQSSHLRSTSSGVFLERIYFYGKIEYLLEVFYNDFQNNLWLFKDPFIHFIRYQGKAILASKDTSLLMNKWKYYFVDLWQYHFYMWSQSGRVRINQLSKYSLDFLGYLSSVRLNPSVVRSQMLENSFIIDNAMKKLDTRIPIISLIGSLSKAKFCNTLGHPISKPTWADSSDSDIIDRFVRICRNLSHYHSGSSKKKSLYRIKYILRFSCVKTLARKHKNTVRAFLKRLGSEFLEEFFTETEEEHVFSLIFPRVFFTSRKLYRGRIWYLDIICINALVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SECA_SHIB3
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SYT_PARPJ
Sequence: MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKIDGELVDTSALIDHDVALAIVTEKDADGLDIIRHSTAHLLAYAVKDLYPEAQVTIGPVIDNGFYYDFAYNRPFTPEDLEKIEKRMQELAKKDEPVSRRVVSRDEAVDYFKSIGEKYKAEIIESIPATDDIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQEAYLHMLEEAEKRDHRKLGKQLDLFHMQDESPGMVFWHPRGWTLWQQVEQYMRRRVNDAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFNHGLRSYRDLPLRYAEFGSCHRNESSGALHGLMRVRGFVQDDAHIFCTEDQFISESIAFNTLAMSVYKDFGFDNVEIKLSLRPDARAGTDETWDRAEQGLREALTACGVTWEELPGEGAFYGPKVEYHIKDALGRSWQCGTLQLDMVLPERLGAEYVAEDNSRRRPIMLHRAIVGSMERFLGILIEHHAGAMPAWLAPMQVVVMNIAESQAEYAQSLAQSLQKQGVRVEADLRNEKISYKIREHTLEKVPYLLVVGDKEREAQTVAVRARGGVDLGVMPPDTFIERLRQDVQSFN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_ANOFW
Sequence: MLWRGVMLYYLLAFVVILIDQWTKWLVVRYMELGESIPIIENVLYMTSHRNRGAAWGMLQGQFWLFYLITIVVVVGIVIYIQRLQPTQRLFGIALGLMLGGALGNFIDRIFRKEVVDFVHTYIFNYSFPIFNVADAALTIGVALMFIYTWTEEKQRKGMSDGANSTHD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y666_MYCPN
Sequence: MEQNNCKIRTWFAKLALAQKVFLGVIPLFFICFVFVIADIVISLQNKGHIIEEIDKFTNQSNVMLLIYACWYVSKPKSHYLKNQQFFLSAFAYIIFTFLGYNVILAASQQAYSDKDAYSLASSVFLHVLAPIAFLVAGIVKMKTDKDVTFNHFWKSLGYFMIYPLVYGLYLATIPYVRGHYVSDDGKSTTYVVYGEITNTKDNPIVAWPVVICFLFIYFPLSFLAVYALQCKLLNRPLKAQFKCATNKCPK
What are the official names of this protein?
Uncharacterized protein MG452 homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: F16PC_CLOBK
Sequence: MTLYDENNLHIIKDNLRYLKLLSKQYPSISSASSEIINLQAILNLPKGTEHFISDVHGEYESFTHMLKNASGVIKRKIDDVFGTSLRECDKKNLATLIYYPEQKLDLIKKSEKNLEDWYKITLYRLIRLCQIVSSKYTRSKVRKSLPSDFAYIIEELLNEQGDRVDKQEYYNSIIETIIDIDRASEFIIAISNVIQRLVVDKLHIIGDIYDRGPGAEIIIEALSKHHSIDIQWGNHDIVWMGAAAGCEACIANVIRISLRYANLSTLEDGYGINLLPLATFAMDFYKEDNCENFKPRTIDKNLNETDIKLLSKMHKAISIIQFKLEGKIIKRRPEFKMEERLLLDKINIKEGTLNLSEKIYKLIDTNFPTLDKENPYELNERERDLVEKLTNSFINSEKLQRHIKFLYSNGSLYLKYNSNLLYHGCIPLNEDGSLKEVTLCKETLKGKSLLDKLDRLAREAYFFKKDPESKLYGMDMMWYLWCGSNSPLFGKKKMTTFERYFLDDKNTHKEEKNPYYKYRNDEKMCTMIFEEFELDADNSHIINGHIPVKTKEGENPIKANGKLLVIDGGFCKAYQPQTGIAGYTLIYNSYGLLLTSHEPFSSIHKAIVEGNDILSSTTILEHVSSRKRVLDTDSGEEIKKQIHDLEMLLVAYRKGLIKEENEANIRF
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: VM2BI_BITGA
Sequence: KYENVEKGDEAPKKCGVTHTNLESDEPIEKASQLFGTSEQQRFDPRHIELVIVADHGMVMKHNGDLTAVRTWLHQIGNNLNVMFADLNIRITMAGLEMWSEKDLIDIQSAASETLRLFGEWRERYLLNRRMHDNAQLLTTVNLDGDTVGLAYVGGMCDPKNSVGIVQDHSRIAREVAATMAHELGHNLGMAHDGNQCNCGANGCVMSEEIIERTSYQFSDCSKEEYRTFLDNHNPQRILNEPLRTDTVSTPVYGNVLQNSPHPCCDPVTCKPKAWEHCISGPCCRDCKFLRPGTVCRVARGDWNDDFCTGRSSECESNPWNFWNH
What is the function of this protein?
In dimer with gabonin-2 (bitisgabonin-2), preferentially inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) and alpha-9/beta-1 (ITGA9/ITGB1) integrins to VCAM-1 and acts also as a strong antagonist of alpha-5/beta-1 (ITGA5/ITGB1).
What are the official names of this protein?
Zinc metalloproteinase/disintegrin.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIe sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CYB_HETGU
Sequence: MKIMRKTHPLAKMVNHAFIDLPMPMNISGWWNFGSLIGMCLIIQIATGLFLAMHYTADTLTAFSSVTHICRDVNYGWLIRNMHANGASLFFICLYLHIGRGIYYGSYLYKETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVIANLLPAIPYIGPDLVEWIWGGFSVDKATLTRFFAFHFILPFIVAALALVHLLFLHETGSNNPLGIPSNCDKIPSHPYYTFKELLGVIMLLGLYLSIVLFFPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVLSILVLALFPFLHTSNQGSLTFRPISQFIFWILVSDLFILTWIGGQPVEPPFILIGQIASILYFFIILILFPVAGLIEDKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CLPP_ALKEH
Sequence: MSDERREGLAPEIEATGLVPMVVEQSARGERAYDIYSRLLKERVIFLVGPVEDHMANLIVAQLLFLESENPDKDIHIYINSPGGAVTAGLAIYDTMQFIKPDVSTVCIGQAASMGALLLTGGTKGKRYALPNSRMMIHQPLGGFQGQATDVDIHAREILDMRDRLNRIMAHHTGQDMETIARDTDRDNFMSPDTACEYGLVDAVLADRKALDQA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEK3_HUMAN
Sequence: MDDYMVLRMIGEGSFGRALLVQHESSNQMFAMKEIRLPKSFSNTQNSRKEAVLLAKMKHPNIVAFKESFEAEGHLYIVMEYCDGGDLMQKIKQQKGKLFPEDMILNWFTQMCLGVNHIHKKRVLHRDIKSKNIFLTQNGKVKLGDFGSARLLSNPMAFACTYVGTPYYVPPEIWENLPYNNKSDIWSLGCILYELCTLKHPFQANSWKNLILKVCQGCISPLPSHYSYELQFLVKQMFKRNPSHRPSATTLLSRGIVARLVQKCLPPEIIMEYGEEVLEEIKNSKHNTPRKKTNPSRIRIALGNEASTVQEEEQDRKGSHTDLESINENLVESALRRVNREEKGNKSVHLRKASSPNLHRRQWEKNVPNTALTALENASILTSSLTAEDDRGGSVIKYSKNTTRKQWLKETPDTLLNILKNADLSLAFQTYTIYRPGSEGFLKGPLSEETEASDSVDGGHDSVILDPERLEPGLDEEDTDFEEEDDNPDWVSELKKRAGWQGLCDR
What is the function of this protein?
Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules.  Regulates microtubule acetylation in neurons.  Contributes to prolactin-mediated phosphorylation of PXN and VAV2.  Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.
What are the official names of this protein?
Serine/threonine-protein kinase Nek3, HSPK 36, Never in mitosis A-related kinase 3, NimA-related protein kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Protein: PDXH_SALRD
Sequence: MSKLADLRQEYARAELSRDHVTDDPIEQFRAWFDEAEDAELEEPNAMTLATAATDGTPSARIVLLKGLDDRGFHFYTNYESRKGTDLSQNPHAALVFLWKPLERQVRIEGTVERLPAEESTEYFHRRPRGAQMGAWASPQSRVVDSRADLEENLDTVKAEYGDEDEIPRPSHWGGYVVRPTEVEFWQGRPNRLHDRLRYRRSDPAGDWTLERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: YSH1_USTMA
Sequence: MAPSVVPQSAAGGAALQASADDQLTIEMLGAGQEVGRSCCVLKYRGKTIVCDTGVHPAFTGIAALPFIDELDWSTVDAILITHFHLDHAAALTYIMEKTNFRDGHGKVYMTHPTKAVYRFLMSDFVRISNAGNDDNLFDENEMLASWRQIEAVDFHQDVSIAGGLRFTSYHAGHVLGACMFLIEIAGLRILYTGDFSREEDRHLVQAEIPPVKPDVLICESTYGTQTHEPRLDKEHRFTSQIHHIIKRGGRVLLPVFVLGRAQELLLLLDEYWAAHPELHSVPIYYASALAKKCISVYQTYIHTMNDHIRTRFNRRDNPFVFKHISNLRSLEKFEDRGPCVMMASPGFMQSGVSRELLERWAPDKRNGLIVSGYSVEGTMARNILNEPDEIIGINGQKIPRRMSVDYISFSAHVDFAQNSRFIDEIKAQHIVLVHGEQNNMSKLRAALQARFTARGSDVKIHTPRNCEPLVLQFRAQRTAKAIGTIAAKPPAQGDIVDGLLISKDFAYTILDPKDLTDFTGLSTSTIVQRQRVALAVSWEMVRWHLQGMYGRLQEGVDAEEGLRTLRIMGAVDVRQSARHELLVEWVSSIANDMVADSIVALLLGIDSAPSSVKMTMHNHHHHHHHHHHHHPGDAKAEETDDDAEATTEDEEARTPTESAANLPMHPFSEAALVAESEVRAKAATDEAVHRDAYQLAKMEHMAAFLEAHFGQVEELVIPEAPISEEIEESVPKVKVETEREAEKDEAGDESMSTLQPEPDSVTDVDKPELAPPAEQATASPPISIASLFDGEARSALRVFLDEAEAVIDVENLVILASSESFRARVQHLCTLALRSFTSLSDAFYLPQQMGTSLFQGKHSQLATIPEFGEERPSKMVRSS
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
Endoribonuclease YSH1, mRNA 3'-end-processing protein YSH1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAS1A_METRM
Sequence: MSKKNYYLLSEGILKRKENTIYFVNEKGSKPLPINKIYSMYAYGQITISSQVISLFAKEGIPIHFFNYYGYYNGSFYPRESLLSGDLLIKQAEHNIDFSKRLKLAKLFVEGAAKNILKVLAYYKIENNIKNTLTELNESSKITEVMNVEGRIRAEYYQYFDDILPDEFKMEGRSRQPPTNMINSLISFGNSMMYASVITELYNTQLNPTISYLHEPAERRFSLALDLSEIFKPIIVDRVIFYLVNKKMITEKDFNQDLNCCLLNDKGRATFVKEYNKRLETTIKHKDLGRKVSYQRLIRLEAYKLKKHVFGMKEYDPFVIWW
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated protein Cas1 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: FTSW_GEOSL
Sequence: MNLGLNVKEIERYDLVILLMAVALTCFGVVMVYSASSVMATKKFHDGFYFLKRQGVYALLGFGVMAVAMRIDYRTWREYAVPILLGCLFLLFLVFIPGIGGAAKGASRWIRLPGFNFQPSELTKIALIVYMAYSLDKKQDKVKFFSTGFLPYMVLLSVVLLILLKQHDLGAALTMGLVAIIMLFAAGTRPRYIIAMGMMALPILYFLVMNVDYRRRRILAYLNPWEDPTDTGFQIIQSWLAFGNGGVLGQGLGEGKQKMFYLPEAHTDFILSVTGEELGLIGVTVIAAMFLMLVLRGVRVALMAQEPFGRFLAFGIATLLGIQSFVNMAVVTGLLPTKGLALPFISYGGSSLIVTLFAVGILLNISTRLKGAP
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: ATPL_UREPA
Sequence: MSSFIDITNVISSHIEANLPAIASENVGSLANGAGIAYLGKYIGTGITMLAAGAVGLMQGFSTANAVQAVARNPEAQPKILSTMIVGLALAEAVAIYALIVSILIIFVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.