PharMolix/UniProtQA huggingface dataset:
Protein: PLSY_BART1
Sequence: MNETEIFFQSTPWFIFLISYLIGSIPFGLLFTKLAKLGDIRTIGSGNIGATNVLRTGNKKVAALTLLCDMLKGAIVVFVIKFFSDPLNKSILISLAGFFAFLGHLFPVWLKFKGGKGVATYLGVCLGVYWPAAIIFIIVWSAIFLLMHYSSLSALVAVTITPIFVFYFSDTYFCCMLIAMSLFVFIKHSANISRLLIGEENKIGTQNRDK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METN_COREF
Sequence: MSTPASTPAPDGSHQRDHHPGTRVEFRGVTKVFTNNKNTETVALDDVSLTVEPGEVIGIIGYSGAGKSTLVRMINGLDTPTSGALLLDGTDIVGMPEAKMRKLRSRIGMIFQQFNLFQSRTAAGNVEYPLELAKMDKAQRKARVREMLDFVGLSDKGRNYPEQLSGGQKQRVGIARALATNPSLLLADEATSALDPETTQEVLALLRKVNKELGITIVVITHEMEVVRSIADKVAVMEAGRVVEYGSVYEVFSNPQTTVAQRFVATALRNTPDMVEEEDLLFHEGRLFTIDLTEDSGFFAASAIAADNGVSINVVHGGVTTLQRQSFGKITVRLTGNPAAIEEFHRSLTRTTTIKEITR
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS3A_COPC7
Sequence: MAVGKNKRLSKGKKGLKKKVVDPFTRKDWYDIKAPSIFETRNVGKTLVNRSQGLKNANDSLRGRIIEVSLADLNKDEEQSFRKIKLRVDEIQGRNCLTNFHGMDFTSDKLRSLVRKWQTLVEAHVDVKTTDGYLLRLFAIGFTKRRPTQVKKTTYAQTAQVRELRKKMFEIITREATSCDLKELVQKFVPEAIGREIEKASRSIYPLQNVYIRKAKILKAPKFDVSKLLELHGDSTDESGTRVTKDFKEPEVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_PONPY
Sequence: MNPLAQPIIYLTVFTGTLITALSSHWFFAWLGLEMNMLAFIPVLTKKTSPRSTEAAIKYFLTQATASMIFLMAILHNNMFSGQWTTANTTNPYSSLMIVTALAMKLGMAPFHFWVPEVTQGVPLTSGLLLLTWQKLAPISIMYQMYPSVDTNILLTLSILSILVGSWGGLNQTQLHKILAYSSITHMGWMVAVLPYNPNITILNLIIYITLTTTTFLILDLNSSTTILLLSRTWNKLTWLMPLISSTLLSLGGLPPLTGFLPKWAIIEEFAKNDNLIAPTIMAIISLLNLYFYARLIYITSITLLPMSNNVKMKWQFENTKPAPLLPTLTILTALLLPISPLILSIP
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CDC22_ARATH
Sequence: MDAGLNRCPLQEHFLPRKNSKENLDRFIPNRSAMNFDYAHFALTEERKGKDQSATVSSPSKEAYRKQLAETMNLNHTRILAFRNKPQAPVELLPSNHSASLHQQPKSVKPRRYIPQTSERTLDAPDIVDDFYLNLLDWGSANVLAIALDHTVYLWDASTGSTSELVTIDEEKGPVTSINWAPDGRHVAVGLNNSEVQLWDSASNRQLRTLKGGHQSRVGSLAWNNHILTTGGMDGLIINNDVRIRSPIVETYRGHTQEVCGLKWSGSGQQLASGGNDNVVHIWDRSVASSNSTTQWLHRLEEHTSAVKALAWCPFQANLLATGGGGGDRTIKFWNTHTGACLNSVDTGSQVCSLLWSKNERELLSSHGFTQNQLTLWKYPSMVKMAELTGHTSRVLYMAQSPDGCTVASAAGDETLRFWNVFGVPETAKKAAPKAVAEPFSHVNRIR
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
What are the official names of this protein?
Cell division cycle 20.2, cofactor of APC complex, AtCDC20.2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CDC20/Fizzy family.
What are the subcellular locations of this protein?
Nucleus.
Protein: QOR_PIG
Sequence: MATGQKLMSAIRVFKFGGPEVMKLQSDVAIPIPKDNQVLIKVHACGVNPVDTYIRSGTHNMKPLLPYTPGLDVAGIVEAVGEHVSSFKKGDRVFTVSTLSGGYAEYALAADDTVYMLPEKLDFKQGAAIGIPYFTACLALLHSACVKAGEIVLIHGASGGVGIAACQIARAYGLKVLGTAGTEEGQNIVLQNGAHEVFNHREVNYIDKIKKSVGEKGIDVIIEMLANVNLSNDLNLLSHGGRVIIVGSRGPIEINPRDTMTKGSSIKGVALYSSTKEEFQQLAAALQAGMEVGWLRPVIGPVYPLEKAAQAHEDIIHSRGATGKMILLL
What is the function of this protein?
Does not have alcohol dehydrogenase activity.  Binds NADP and acts through a one-electron transfer process.  Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro).  May act in the detoxification of xenobiotics.  Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability.  NADPH binding interferes with mRNA binding (By similarity).
What are the official names of this protein?
Quinone oxidoreductase, NADPH:quinone reductase, Zeta-crystallin.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_SHEPW
Sequence: MLFAQLNEYMAEVGLDASEQQKKQLVDFVGMLNKWNKAFNLTSVRDPEQMLIRHIMDSLVVSPHLKGSRFIDVGTGPGLPGIPLAILNPDKEFVLLDSLGKRIRFQKQVQFELGINNISSIESRVEAYQPEELFDGVLSRAFASIQDMLQWCHHLPKSDGCFYALKGQLSEDEMANMPQGFRVTDTIELVVPKLDEQRHLLRVVKQD
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_DECAR
Sequence: MKRTRTSKAWMREHINDTYVQLARKEGWRSRAAFKLMEMDDKDKLLKHGEVVVDLGATPGGWSQVAVKRVGDGGLVFALDLLEMEPIHGVHFIQGDFREDEVLQQLEEQLGERRVGLVMSDMAPNMSGVPLVDQARIMHLAELGLEFSRVHLKPEGAFLVKVFQGTDYETFLKQMRETFKTVAVRKPDASRDRSPELYLLGRTLR
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O268_CONPE
Sequence: MQKLIILLLVAAVLMSTQALFQEKRLKEKINFLSKEKADAEKQQKRYCSDQWKSCSYPHECCRWSCNRYCA
What are the official names of this protein?
Conotoxin PnMEKL-032.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YN12B_YEAST
Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKIQEYDKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSDWSFYGRPSMIPYTPYQMSPMYFPPGPHSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFLNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQKLTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAQTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYQSFIASNEIQQSDDLNFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISKSDILPSKKRSSTPQISDIESTGSGGMHRLDVPLLAPMSQSNTHESSHTSKSKDFRHSDSYSDNETNHTNVPISSTGGTNNKTVPQTSEQETEKRIIHRSPSIDTSSSESNSLHHVVPIKTSDTCPKENTEESIIADLPLPDLPPEPPTKLSDSFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDKYYDRKEIDPKRVINSMFIFNRKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIEQCDMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRSKYMKLGMEKSLTEKLPKLNVHLNPKGKKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTKPDNKLVAISDASYGNQPYYKSQIGNIFLLNGKVIGGKSTKASLTCTSTTEAEIHAVSEAIPLLNNLSHLVQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-NL2 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: C1TM_YEAST
Sequence: MLSRLSLLSNSRAFQQARWRIYRLKVSPTVHASQYHILSGRKLAQSIREKANDEIQAIKLKHPNFKPTLKIIQVGARPDSSTYVRMKLKASKDSNVDCIIEKLPAEITEVELLKKISDINDDDSIHGLLIQLPLPRHLDETTITNAVDFKKDVDGFHRYNAGELAKKGGKPYFIPCTPYGCMKLLEEAHVKLDGKNAVVLGRSSIVGNPIASLLKNANATVTVCHSHTRNIAEVVSQADIVIAACGIPQYVKSDWIKEGAVVIDVGINYVPDISKKSGQKLVGDVDFDSVKEKTSYITPVPGGVGPMTVAMLVSNVLLAAKRQFVESEKLPVIKPLPLHLESPVPSDIDISRAQSPKHIKQVAEELGIHSHELELYGHYKAKISPNIFKRLESRENGKYVLVAGITPTPLGEGKSTTTMGLVQALSAHLGKPSIANVRQPSLGPTLGVKGGAAGGGYAQVIPMDEFNLHLTGDIHAISAANNLLAAAIDTRMFHEATQKNDSTFYKRLVPRKKGIRKFTPSMQRRLKRLDIEKEDPDALTPEEVKRFARLNINPDTITIRRVVDINDRMLRQITIGEAATEKGFTRTTGFDITVASELMAILALSKSLHEMKERIGRMVIGADYDNKPVTVEDIGCTGALTALLRDAIKPNLMQTLEGTPVMVHAGPFANISIGASSVIADLMALKLVGSEKNPLNDKNIHEPGYVVTEAGFDFAMGGERFFDIKCRSSGLVPDAVVLVATVRALKSHGGAPNVKPGQSLPKEYTEENIDFVAKGVSNLVKQIENIKTFGIPVVVAINRFETDSQAEIEVIKKAALNAGASHAVTSNHWMEGGKGAVELAHAVVDATKEPKNFNFLYDVNSSIEDKLTSIVQKMYGGAKIEVSPEAQKKIDTYKKQGFGNLPICIAKTQYSLSHDPSLKGVPRGFTFPIRDVRASIGAGYLYALAAEIQTIPGLSTYAGYMAVEVDDDGEIEGLF
What is the function of this protein?
Mitochondrial isozyme of C-1-tetrahydrofolate synthase.  The trifunctional enzyme catalyzes the interconversion of the one-carbon derivatives of tetrahydrofolate (THF) between different oxidation states by the enzymatic activities 10-formyltetrahydrofolate synthetase, 5,lO-methenyltetrahydrofolate cyclohydrolase, and 5,lO-methylenetetrahydrofolate dehydrogenase.
What are the official names of this protein?
C-1-tetrahydrofolate synthase, mitochondrial, C1-THF synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CHMP5_RAT
Sequence: MNRFFGKAKPKAPPPSLTDCIGTVDSRAESIDKKISRLDAELVKYKDQIKKMREGPAKNMVKQKALRVLKQKRMYEQQRDNLAQQSFNMEQANYTIQSLKDTKTTVDAMKLGVKEMKKAYKEVKIDQIEDLQDQLEDMMEDANEIQEALGRSYGTPELDEDDLEAELDALGDELLADEDSSYLDEAASAPAIPEGVPTDTKNKDGVLVDEFGLPQIPAS
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.  ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released.  The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.  ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4 (By similarity).
What are the official names of this protein?
Charged multivesicular body protein 5, Chromatin-modifying protein 5.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endosome membrane; Peripheral membrane protein. Midbody. Note=Localizes to the midbody of dividing cells. Localized in two distinct rings on either side of the Flemming body.
Protein: NEGR1_MOUSE
Sequence: MVLLAQGACCSNQWLAAVLLSLCSCLPAGQSVDFPWAAVDNMLVRKGDTAVLRCYLEDGASKGAWLNRSSIIFAGGDKWSVDPRVSISTLNKRDYSLQIQNVDVTDDGPYTCSVQTQHTPRTMQVHLTVQVPPKIYDISNDMTINEGTNVTLTCLATGKPEPVISWRHISPSAKPFENGQYLDIYGITRDQAGEYECSAENDVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRSGLIRCEGAGVPPPAFEWYKGEKRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLGTTNASLPLNPPSTAQYGITGSACDLFSCWSLALTLSSVISIFYLKNAILQ
What is the function of this protein?
May be involved in cell-adhesion.  May function as a trans-neural growth-promoting factor in regenerative axon sprouting in the mammalian brain.
What are the official names of this protein?
Neuronal growth regulator 1, Kindred of IgLON, Kilon, Neurotractin.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CH60_HISS2
Sequence: MTAKDVKFGNDARVKMLAGVNVLADAVKVTLGPKGRNVILDKAFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVSEGLKAVAAGMNPMDLKRGIDKAVNAVVEELKILSKPCETSKEIEQVGTISANADETVGKLIAQAMEKVGKEGVITVEDGSGLSDELDVVEGMQFDRGYLSPYFINKPEAATVELDNPFILLVDKKISNIRELLPVLEGVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAILTAGTVISEEIGMELEKATLEDLGQAKRVVINKDNTTIIDGIGDEAQIKGRVAQIRQQIEEATSDYDKEKLQERVAKLAGGVAVIKVGAATEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAATKVATTLKGDNEDQDVGIKLALRAMEAPLRQIVTNAGEEASVVASAVKNGEGNFGYNAGTEQYGDMIAMGILDPTKVTRSALQFAASIAGLMVTTECMVADLPKEEKADLTGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_PARP8
Sequence: MARTQVPDPATSAPAERALWLRDELERANYAYYVLDQPDLPDAEYDRLFKELQQIESEHPDLITPDSPTQRVGGEVASGFRPVVHDMPMLSLNNGFSDEDIAAFDKRVSDTLHHTPVDYACELKFDGLAISLRYVDGQFTQAATRGDGATGEDVTENVRTIRSIPLKLKGKRVPKLVDVRGEVLMFRRDFDKLNQRQRDAGQREFANPRNAAAGSLRQLDPKMTAQRPLSFFAYGIGVLDGIEMPGTHSELLDWYHEMGLPVNSERAVVQGAEGVLGFFHKVGEKRDKLPYDIDGVVYKVNRRDEQDALGFVSRAPRFALAHKFPAQEALTKLIAIDVQVGRTGAITPVARLEPVFVGGATVTNATLHNEDEVRRKDIRIGDTVIVRRAGDVIPEVVGALLERRPPDAREFVMPTQCPVCGSAIERLPDEAIARCSGGLFCPAQRKQALWHFAQRRALDIDGLGEKIIDQLVELNLVRTPADLFNLGFATLAELDRFAEKSAQNLIDSLEKAKHTTLARFIYALGIRHVGESTAKDLARHFGSLDPIMSATVEELLEVNDVGPIVAEAIHQFFAEEHNRTVIEQLRAPGKVTWAEGPPAPKAPQGVLAGKTVVLTGTLPNMGRDEAKELLEAAGAKVAGSVSKKTDYVVAGAEAGSKLAKAEELGIPVLDEDGMRKLLEGQTT
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SINL8_ARATH
Sequence: MVGALEALISQGHGGERVAKRQRSATLLDLDILDCPICCEGLTCPIFQCENGHLACSSCCPKLRNKCPACPMENILESILVTCPNDMFGCTESFLYGKKSTHEEECIFSLCSCPSLDCEYSGRYEDLYDHYKLTHISNSYWTTNCFRSSIPYKAPMLISDKIQITRVYEKKILFAVQCFRESCGVYVTVSCIAPSAPEVGQFSYQISYTVDEHTMVYRSPQMKRVRKVSFETPQENFMLIPHNLLRSELLDIKLSIVETSNQE
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  It probably triggers the ubiquitin-mediated degradation of different substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase SINA-like 8, RING-type E3 ubiquitin transferase SINA-like 8, Seven in absentia-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
Protein: SYY_SALHS
Sequence: MASSNLIKQLQERGLVAQVTDEDALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVAKIRKQVAPFLDFDCGENSAIAANNYDWFGSMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDQGISFTEFSYNLLQGYDFACLNKLHGVALQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMDIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLVAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDAELQPSRGQARKTIASNAVTINGEKQSDPEYIFNDEDRLFGRYTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBCC1_XENTR
Sequence: MDDSRVQLWVKTDPFLLGALQIPPPEKFSMHYLRKMATYVRTRASEGCYPRLCWCMWRHIACGKLQILEETAWLYFETFLSVFERSVAESLNWAEVASTCPSSEKYEEVKSKLSVDTLKFMLFLYIQQINKISLRSPLIGNEWPSPRGRSPISDFAAQSSFYNKVWDDYSHYNFIHNHLTYILELLMEPNQLSKVSQFSHCILISAEVVTALGFVIEGTVDKNRVVNAFLDLAIWQPVQIKSGFIETLGSFSFQKLQAWIKECLVINPFGITSCIKSGTKLSWAQQVDGLNKRAKVACNTYKVPHTHRMVVMSQISKQTLAKSSKTLVDARVKIHRCSDCYIYLLSPLRSVTVEKCQNCTIVLGPVQTVLHIQMCYNVKIIAVCQRLSLLSTTNCTFHVLTPTRPLFYCGNQGVVLAPFHISYSMLEDHMAHTGLATVPNSWDRPFFFSTESSNSHIWRLLLPEEFFTFVVPFEMEGDTTEIPGGLPPAYSTSVQQRQQKIRMWQETVKDAGLTREQRKQLQAVVEMKFNEWLIKTENRHQLDSLVS
What is the function of this protein?
May play a role in the regulation of centrosome and Golgi apparatus positioning.
What are the official names of this protein?
TBCC domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TBCC family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.
Protein: HISZ_DEHM1
Sequence: MIARCKGCSDLLPEDMLRFRYIESIFHDSCITWGYEEVRTPMLEYLSLFTSSGTLTPQMLKRVYSFLDWDGWSGERVVLRPDGTIPAARLYIDNLQEMEVARLCYTSNIFRFDETGKKSRENWQLGAEIIGVTGSEANAELITLALETLSRLGFEDVELRLSHSQLIKAVLAQLEPNADEQHKIFDQLLDGDVALMSRLEAEKPELFRTLKLLMENKGTSAAFLKNVMAMAGAAGGDLEEPLNDFIAGVDVLDKLGVSYQIDLASGKGFEYYTGVIFHLFVNGEHVGGGGRYDKLIPLLGGPDKPAAGFALYLNRLIPMIDAEDMYDMVEEKILIKYEGDNLKNAYEMANLIRECGISAELFYPGVDTAAYGWAVTVKAADSYEVTDLIEDKTTEFKNQAEVICLLSGEEDA
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_NEIMH
Sequence: MAITKEDILEAVGSLTVMELNDLVKAFEEKFGVSAAAVAVAGPAGAGAADAEEKTEFDVVLASAGDQKVGVIKVVRAITGLGLKEAKDIVDGAPKTIKEGVSKAEAEDIQKQLEEAGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: SYP_ANADF
Sequence: MPVVRLSQAFVPTLKEAPADAQVASHKLLVRAGFIRQLGAGIYDYLPLAKRTLAKIEAIVREEMDAIGGQEFYLPALHPAEIWKESGRWEVMGDNMFRLKDRKNGDYCLGMTHEEIFTAIARDELRSYRQLPQVWYQIQTKFRDEPRPKSGLLRVRQFTMKDAYSFDVDRAGLDKSYEDQRRAYERIFTRCGLDFVAVQAHSGAMGGSESSEFMVRTDAGEDLVAACPRCRYAANTETATSRLASEQDGAGLPKPEKFATPGVVTIEALEQPPYGVAARRQLKTLVYVADEKLVVAVVRGDQELNEAKLQTATGAQVIRPAHPEEIPSLMGARAGSLGAVGFSRAKVFVDPSLADRKDMVTGANEDGFHLRGVEVRRDVLTGPHATVAELRTVRAGEGCPRCDGTLDVFKALEVGHIFKLGTKYSESMKATVLDADGKAVPIVMGSYGIGVERIMAAAIELHHDELGIRWPPAIAPFQATVLTLGPEPELKKAADELVKALSDAGLEVLHDDREERAGVKFKDADLVGIPLRISVGKKGLAEGKVEWKLRGDKAVELVPLAEVARRAAEHVRAGR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_RICM5
Sequence: MNNLKQGKFITFEGGEGIGKSTQSQMLYEYLQSQNTPVILTREVGGTIVAEKMREILVHEELLPMSELLQAIAARYDHMARKIIPALQEGHIVICDRFIDSTACYQGLELENGIDLVYNLHKTLMPSLMPDITFFIDVEPDTAIKRVNSRNMSNKFDIRGIDFYKKIYDCFKELSNRFPERIKTIKASDLSPLEVHELIKKHL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ALR_SALTO
Sequence: MWQAEVRVDLDAIRENVSWLRSGSAAELMAVVKGDGYGHGMVPAAHAALDGGADWLGVCTLDEALTLRRAGITVPVLAWLLAPGLPLHEGVTAGIDLGVASVAQLEEMVEAGRVAGRPARLHLKIDTGLSRGGATISEWPELLDAAAKAQADGAVEVVGVWSHFVYADAPGHPTTDRQLAVFHEGLGMVEKAGLRPRYRHLANSAATLTRPDAHFDLVRPGLAVYGLSPVAGERFGLRPAMTARARVMLTKQVPAGAGVSYGHTYTTDRASNLAVIPLGYADGVPRDASNSGPVQLGGVRRTISGRVCMDQFVLDCGDDPVAPGDVATLFGTGRDGEPTADDWAEAVGTINYEIVTRFGSTRVPRCYDGERP
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.