PharMolix/UniProtQA huggingface dataset:
Protein: KUP_SHIDS
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVIRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFLLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTEVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_CANAS
Sequence: MPHQQMLILFGLLPVATNISTWWNFGSMLLTCSALQVMTGFSLSMHYTANINLAFCSIIHITRDVPHGWVMQNLHAIGASMFFICIYMYIARGLYYGSYLNKETWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTMTTWLWGGFAINDPTLTRFFALHFILPFGIISVSSIHIMLLHEDGSGNPLGTNSDIDKIPFHPYHTYKDILMISIMIITLLLTVSFFPDIMNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALVMSIMILFTMPFTHTSPMRSLTFRPLMQFMFWTLVATFVIITWTATKPVEPPFTTISQVASIIYFTFFMSNPILGWLENKITKHN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CA14_CONPL
Sequence: MFTVFLLVVLATTVVSFPSDRDPASNHENSKGSNRNAWFTPEECCAAPACRGMILEFCLAGEAFAAALDGFRRLPYRLSSE
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them (By similarity).  Has possibly a distinct nAChR binding mode from other alpha-conotoxins, due to a different three residue motif (lacks the Ser-Xaa-Pro motif) (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Pu1.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7S_XANOR
Sequence: MAKKSLNETSPVARFEQSLEELEQLVQKMEVGDLSLEQSLTAYERGIGLYRDCQQALEQAELRVRLLTDPARPELAQAFEPPSLDG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_PSYWF
Sequence: MADKTVKELADMVSKTVSAVQKQLTDAGLPARGEDDLVTELEQEQLVAFLKQSHGQKEKRRISLKSKTTSTARVTGSSGKSKSVNVEVRKKKVFEKPDPNKLAEEIAAREQAALEAKKRAEEEAKKREQVKKEAEERQAATLAAMRANLGGGSSSSDKKEELSTVVVKKGSKAAAAAKEAPKKKVAQTKPKVETAAERKARETREAEEERLRQIEAETRRKQAEEAQKKTLEQMRKMAGKYSDKDPVAEVRKDEPLAEGLVGEALEESFEKERREIKRGSASTATRGRRRKGQEEREIRNRKHGLKSSQASQHKFEKPVEKIVHDVEIGEQIVVSDLAQRMAVKAREVTKLLMKMGEIVSADQEIDQATASLIVEEMGHNPIPVSDTKVEDDLQEAVEERRSNVQTRPPVVTIMGHVDHGKTSLLDKIRETKVATGEAGGITQHIGAYHVETDRGVITFLDTPGHAAFTAMRSRGAQATDIVILVVAADDGMMPQTEEAIDHARASGTPLIVAINKMDKSTADPDRVLNELTTKEVVTEAWGGDVPMAKISAKTGEGIDELLELINLQAELMELEAPTDGAAQGVVIESRLEKGRGAVASILVKKGTLNQGDLVLAGEFYGKVRAMTDETGKRVKSAGPSIPVEILGLPDTPAAGSEFLVVSDEKKAREVAEFRATRERERQLERQNKMRLESMFEQMGQDDLSFLNIILKTDVRGTLEALLAALEDLSTDEVKVKVISSGVGPIAESDVTLAESSEAVLLGFNVRADNAAKRKADEAGIDIRYYSVIYGLIDDVKAAMSGMLSPEHREKILGIAEVRDVFRSSKFGAAAGCMVVEGTIYRNKSIRVLRDDKVAFTGQLQSLRRYKDDVNEVRSGMECGLAVRGYDVEVGDKIEVFEIQEIQRTI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_CLONN
Sequence: MEVLIIIFGIILDRITKLWALKELSSGHEIEIIKNFFSFNYLENRGAAFGIFQGKTVLLVLVTLLIMIGVIYYFIKYRPTSRFMRIGVSFIVSGALGNLYDRIFYKYVVDFILIHYKNVYYYPTFNIADILVVVGTIMLAIFLLREGK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROQ_GEOUR
Sequence: MKILVLHGPNLNMLGTREPEVYGKMTLDDIDSTLKELACELGVELTIYQSNSEGALVDKIQSAVGSFDGILINPAAYTHTSVAIRDAIAATALPTVEVHLSNIHSREEFRTKSFVAPIALGQISGFGADSYLLGLRALFNHNKK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: DTD_SHEHH
Sequence: MIALIQRVSEAKVVVDGATIGEIDRGLLVLLGVEREDNIEKMQKLATKVMSYRVFSDENGKMNLNLEQAGGSLLVVSQFTLAADTGRGLRPSFSGAGTPEQARELYEAFIDFCKSKGVNTQTGQFAADMKVSLVNDGPVTFNLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_METC4
Sequence: MAQKQTPSGPTQRQQRVAELIRHALAEVLQRGDIQDPVLGSHVVTVPEVRMSPDLKLATAYVMPLGGQDEAPVIAALERHKKILRQEVARRVNLKFAPDLRFRRDETFDEAARIDQLLRSEKVQRDLESAPREDDEGEPASSSRD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERA_STAES
Sequence: MTQNSYKIPIQGMTCTGCEEHVTEALEQAGAKDVSADFRRGEAIFELSDDQIEKAKQNISAAGYQPGEEESQPSENSVDFNRDGDYDLLIIGSGGAAFSAAIKANENGAKVAMVERGTVGGTCVNIGCVPSKTMLRAGEINGLAQNNPFTGLQTSTGAADLAQLTEQKDGLVSQMRQEKYIDLIEEYGFDLIRGEASFIDDKTIQVNGQNITSKSFLIATGASPAVPEIPGMNEVDYLTSTSALELKEVPQRLAVIGSGYIAAELGQMFHNLGTEVTLMQRSERLFKTYDPEISEAIDESLTEQGLNLITGVTYQKVEQNGKSTSIYIEVNGQEQVIEADQVLVATGRKPNTETLNLESAGVKTGKKGEVLTNEYLQTSNNRIYAAGDVTLGPQFVYVAAYEGGIVANNALGLAKRKIDLRFVPGVTFTNPSIATVGLTEQQAKEKGYDVKTSVLPLDAVPRALVNHETTGVYKLVVNAQTQKLIGAHIVSENAGDVIYAATLAVQFGLTIEDLTDSFAPYLTMAEGLKLAALTFDKDVSKLSCCAG
What is the function of this protein?
Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase.  MerA protein is responsible for volatilizing mercury as Hg(0) (By similarity).
What are the official names of this protein?
Mercuric reductase, Hg(II) reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: ABR1_ASPFU
Sequence: MFHSRALLLSWLVGFTAAKDIHLDWNITWVWAAPDGFGRPMIGINNEWPCPIVNADLGDRLIVDVHNGLGNQSTGIHWHGFHQYMTGTMDGSNQVTQCALPPGSSMRYEFDVNQTGTYWYHSHEMGQYPDGLRGPFIVRDPSPPFAYDDEFTLTLTDHYHEQMSVLLQQYEADSVGAQAGVNEPLPAAALINEGFDTTTLRVEPNKTYLIHLVCVGNWPGHVIVFDDHEISVVEVDGTWVDAYPARDKKIRLATGQRMSILLKTKDNTDRNYAIWDSMDVNMMFFYQNRAIPEGFNPNTTAWLVYDEAKELPPAPDVHELDPNNDFVDDLVFVPASHEPLLEKVDRQIIFDTGVTQRDGRSVYTINGQTYVDPEEPTLYTALAASPENASNASLYGQVNPFVVQYGEVVEIIINNHHGNLHPWHMHGHQFQVLQRTIPEGGYFDGYFANISSTPVKRDTIMVQNHGHAVLRFRANNPGVWLIHCHIEWHVTKGLTGTLIEAPAQMHKISVPLDHQRICPSYGTPPGGTPSSPPHDAPRPDGASGSPQYPPKPWGEPDASAPEQDDSQPGGTPDSPEDFPQPWGEPEESPQEPPQPWSPSNNAQPPANTYAPEYPSGYVPVAPGPVIIDSELHYGGKSSHVECSGVNAGHTQDTTTGGDGCANAS
What is the function of this protein?
Multicopper oxidase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment and a structural component of the conidial wall (PubMed:10515939, PubMed:14970241, PubMed:19156203).  The first step of the pathway is the production of the heptaketide naphtopyrone YWA1 by the polyketide synthase alb1 though condensation of acetyl-CoA with malonyl-CoA (PubMed:10515939).  The naphtopyrone YWA1 is then converted to the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN) by the heptaketide hydrolyase ayg1 though chain-length shortening (PubMed:10515939).  1,3,6,8-THN is substrate of the hydroxynaphthalene reductase arp2 to yield scytalone (PubMed:10515939).  The scytalone dehydratase arp1 then reduces scytalone to 1,3,8-THN (PubMed:10515939).  1,3,8-THN is also substrate of the hydroxynaphthalene reductase arp2 to yield vermelone (PubMed:10515939).  Vermelone is further converted by the multicopper oxidase abr1 to 1,8-DHN (PubMed:10515939).  Finally the laccase abr2 transforms 1,8-DHN to DHN-melanin (PubMed:10515939).  DHN-melanin biosynthesis appears to be initiated in endosomes where early enzymes (abl1, ayg1, arp1 and arp2) localize, with exocytosis leading to melanin deposition on the cell surface where late enzymes (abr1 and abr2) localize (PubMed:26972005).  DHN-melanin is an important structural component of the outer cell wall and is required for the presence of conidial surface hydrophobins (PubMed:19703288).  DHN-melanin also plays a crucial role in fungal virulence, including a protective role against the host's immune defenses (PubMed:19156203, PubMed:20145078, PubMed:21747802, PubMed:21573171, PubMed:24818666).  DHN-melanin protects also conidia against amoeba predation (PubMed:25684622).
What are the official names of this protein?
Multicopper oxidase abr1, Conidial pigment biosynthesis oxidase abr1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted. Cell surface. Note=Localized at the surface of stalks and conidiophores, but not in young hyphae (PubMed:24123270).
Protein: SYFB_MYCGE
Sequence: MLISKKTLGVLIPDIFSFSNDQIAQKLEQMGIEVESIKQFNSPDYLQLAKVVSIQPHPHDNKLFICELQIDKNKFINVVSNANNINNPDNINKFVIVAKKGTELLNGLIVKTQNIKGIISEGILCSYIDINPFSRQIIEKTEVADAIIIDHVSNDHDWNQYLSFLSLDDVIFDVKTPTNRADLHSLIFLAKELGVLLKTKTFLKQKSSVVNHDFFKFPLNLKNKLKANYFGGLFLRQINQHSSPWTVKGLLINQMIKPVNYYVDKANLVTVFTAQPIHCHDADRIVGNIELKQATHNETFVGLDDKQYEIEPGDIVVCDEKGIIALVGIIGSKRTMVQPTTTNIFFEVVNCNSETIKQTAKRFLINNFASKFMVKPISLLATDNCLNYLQNSLLTTDNIGKISHFSSSLKVEPFSKKLTVNFHKIRQLIGIEKKELTDQTIKKSLSQLGFKVDNQLLKIPSYRQDINTWQDISEEIVKLIDINKLKPIGITSSFNFEKSSYFNTFNALTKLRKKLQTLGFHNVITYQLTDQKSAKTFNLFNLENFITIKNPVSQNHSVMRVSLIDSLLKVLKTNNNYKNELVNIFEFSFIKTQNNSELHLAVLWVEKLFTSSFNPMQGISNDVFTMKGLAKLIVANLGFSCDFEPLDDSDYFVNNQSLKIVVFNEQIGFIGLIKESLLNNYDLNNKPIYCLEINLDRMLSSLNRIEKNYLGYSKLQPVCKDLTFSFTNPASHFDQFANMIKRITGIESWKLISVFETMQNNQLITKYTVRYFLKNDANKPLTNQTIELITNNLKLQCEKLKIKLDI
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAS16_CAEEL
Sequence: MGNLFKFSLNCIKYRSENLEKSKMFYQYFYFHLTLSIVLIYGSDIGKDANEHMSSVPKKIIIEGTRQKRQVVTKLFSPQWSNAKVFYCNADSFSKLQLKKLKLKKNSDTVKRKLMKFAMNFISSQTCVTFEENCTISTRIKFVDSTFCASYVGMINSVQEIYFPDWCMRFGSAVHELMHALGVLHTHARFDRDNFLNVNLNKDDEDDSNFEIVSPPFSINVVPYEYGSTLHYTADVSGTNSLLPKQMEYYRTLGNRRVTFYDMLTINTAYNCKCPSELLCANGGYTNPSNCLECICPLGYGGVLCDRVVACSVQLSADSYWKGSWISVGSSVLRDTTDPVKAFISINAPKDKIIEVKIVKIENFSCDSGCNNNGVEIKYMGDPRITNPIICCENQVDPSNKGYKAKLNPLLINIYTFLGKNKVTFHYRYVNERLSSYNKTTNGYDNYEYYA
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-16, Nematode astacin 16.
What are the subcellular locations of this protein?
Secreted.
Protein: RS13_COXBR
Sequence: MAARIAGVNIPVQKHARIALQAIYGIGNSRALEICKEAKIDPATKVKDLSEAELDALRTEVGKFSVEGDLRRERSMDIKRKMDLGTYEGIRHRRGLPLRGQRTRSNARTRKGKRKPIRS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GUAA_MACCJ
Sequence: MEMAFEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTVDPEIFNLGVPVMGICYGMQLMTKLLGGSVERANEREYGKAVIKAETHSLFTKLPEEQTVWMSHSDKVINLPEGFNVIAHSPSCKYAAIENPERNLYGVQFHPEVRHSEYGNDLLRNFIREICKCTGEWTMENFIEIEIEKIREKVGDRKVICAMSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEGDMVMKQFGEGFNMNIIRVDAKERFMSKLAGVSDPEQKRKIIGNEFVYLFDEEAAKLKDADFLAQGTLYTDIIESGTKTAQTIKSHHNVGGLPEDMQFELIEPVNTLFKDEVRALGIELGIPEHLVWRQPFPGPGLGIRVLGEITEEKLEIVRESDAILREVIAEEGLERDIWQYFTVLPDIRSVGVMGDYRTYDYTVGVRAVTSIDGMTSDFARIDWEVLQKVSSRIVNEVDHVNRVVYDITSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RPAB5_BOVIN
Sequence: MIIPVRCFTCGKIVGNKWEAYLGLLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC5, RNA polymerases I, II, and III subunit ABC5, DNA-directed RNA polymerase III subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
Protein: NRDR_CALBD
Sequence: MRCPFCGYEDSKVVDTRPTNEGKTIKRRRECLKCQKRFTTYEKIEKQPILVIKKDNRREEFDRNKILNGIIKACQKRPVSIEQMNKIVDEIENEIYNSMREEISSREIGEMVMEKLKKIDEISYVRFASVYRQFKDINTFIEELQKLLTEKIE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: CYB_THODA
Sequence: MTIMRKNHPLLKLINHSFIDLPTPSNISSWWNFGSLLGICLIIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYMLLKTWNIGIXLFLTTMPTAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSTNPSGLNSNSDKIPFHPYYTIKDLLGVLLLLMVLMILVLFFPDILGDPDNYTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAAFPLLNSSKQHGLVYRPITQFLYWIFIANLLILTWIGGQPVEYPFTLIGQISSILYFAIIVILMPLASMIENNILKLHD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPPC2_NEMVE
Sequence: MLGNYYFAIVGHYDNPVYEKEFNQQMKMDSNDHRHLNQFIVHAALDLVDESMWGTTGMYLKSVDKFNEWFVSAFDPPLSWIIDPQFFLDLTSWMRFMMLHDVKNDDGIKNFFSDVYETFIKVLMNPFYEINSKIKSANFDKKVLLAAKKHILP
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Probable trafficking protein particle complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. Sedlin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Endoplasmic reticulum. Golgi apparatus.
Protein: HRCA_LACLA
Sequence: MITERQRQILNLIVSLYAKEHTPIGSKSLLDSIQASSATIRNDMKVLEKLGLIQKEHTSSGRVPSVSGYKYFVENVIQLDEFSQNDLFKVMKAFDGDFYRLSDLFKTAAKSLSGLTGLTSFVLNAPQRDQQLVSFEMVMLDSHSVLSVITLGTGEVRTNQFILPKSMTEADLAVFSNLVKERLVGKKVIDIHYTLRTEIPQIVQRYFKVTSEVLQLFESIFDDLFKERLTVAGRKNIFDYATDNLAELYKLFSDDERMLHEIREITNNDEMRAVKFDNDEKYMKNLTIISQKFVIPYRGFGTLTVVGPVEMDYQRTLSVLDLVAKVLTMKLSDYYRYLDGNHYEISK
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: OST1_SCHPO
Sequence: MLVLKLLLWSIISGLSLAEQVWRNSNAIRTIDLRSTYTKTLTSLIIVNEGDEPQNTYRYFQQTSPGESVLSLSVSIKEEEKKGTNPIKVNNNVYDIPLQPPVKPGESRTLLIQAGLDGGVRPLPAAVDQDEEQYLVYLTTLYLDSPYTTDLQRTRLILPSAKIDTYTTYNIDGAELPNRVGNTLVYESRETITGEDNDLGEIYVRYEHTVPIPRGADLYVQIDMHEYRKMLEVSERVVFENHAAKLKSNFDRAKWYMGNFYNPVSTAINRVVYSLPRNSKDVYYTDEVGNITTSHMRVEPHQTWIELNPRYPVFGGWNYLFQLDWKMPYEEFRSSKNRREYLDIPLAWSPGDMIYEKAVWSYVFPEGATNIEIEMPVEISNSNVTKIHKFLDTLGRQVFTYEALNVTDGVPSDIVHISYEYNSSAFFLRIAIITTLLILLAAAAYMIWAP
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Oligosaccharyl transferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: PREB_RAT
Sequence: MGRRRGVELYRAPFPLYALRIDPKTGLLIAAGGGGAAKTGIKNGVHFLQLEQISGCLSASLLHSHDTETRATMNLALAGDILAAGQDAQCQLLRFQIHQQKGSKAEKSGSKEQGPRQRKGAAPAEKKSGAEVHPEGVELKVKNLEAVQTDFSTEPLQKVVCFNHDNTLLATGGSDGHVRVWKVPSLEKVLEFKAHEGEIGDLALGPDGKLVTVGWDFKASVWQKDQLVTQLQWQENGPTSSNTPYRYQACRFGQVPDQPGGLRLFTVQIPHKRLRQPPPCYLTAWDSSTFLPLQTRSCGHEVISCLTVSESGTFLGLGTVTGSVAIYIAFSLQRLYYVKEAHGIVVTDVTFLPEKGCGPKLLGPHETALFSVAVDSRCQLHLLPSRRSVPVWLLLLLCVGLIIVTILLLQSAFPGFL
What is the function of this protein?
Was first identified based on its probable role in the regulation of pituitary gene transcription.  Binds to the prolactin gene (PRL) promoter and seems to activate transcription.
What are the official names of this protein?
Prolactin regulatory element-binding protein, Mammalian guanine nucleotide exchange factor mSec12.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus. Note=Concentrates at endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER).
Protein: PYRF_HALHL
Sequence: MSVPGPPRLVVALDFPAAAPAEALAAQLDPRLCRLKVGKELFTRAGPQLVERLHARGFEVFLDLKYHDIPNTVAGACRAAADLGVWMVNVHALGGRRMLEAAAEAVAAAEGRTLITAVTVLTSHDAATLEEIGLAGPPREAVLRLAGLAQASGLDGVVCSPEEAAAIGERFGAGLLRVTPGVRPAGAALGDQQRIATPAAAVAAGCDHLVVGRPITAAEDPAAAAAAIAAEIAAAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: AMYB_PAEPO
Sequence: MTLYRSLWKKGCMLLLSLVLSLTAFIGSPSNTASAAVADDFQASVMGPLAKINDWGSFKKQLQTLKNNGVYAITTDVWWGYVESAGDNQFDWSYYKTYANAVKEAGLKWVPIISTHKCGGNVGDDCNIPLPSWLSSKGSADEMQFKDESGYANSEALSPLWSGTGKQYDELYASFAENFAGYKSIIPKIYLSGGPSGELRYPSYYPAAGWSYPGRGKFQAYTETAKNAFRTAMNDKYGSLDKINAAWGTKLTSLSQINPPTDGDGFYTNGGYNSAYGKDFLSWYQSVLEKHLGVIGAAAHKNFDSVFGVRIGAKISGLHWQMNNPAMPHGTEQAGGYYDYNRLIQKFKDADLDLTFTCLEMSDSGTAPNYSLPSTLVDTVSSIANAKGVRLNGENALPTGGSGFQKIEEKITKFGYHGFTLLRINNLVNNDGSPTGELSGFKQYIISKAKPDNNGGTGNKVTIYYKKGFNSPYIHYRPAGGSWTAAPGVKMQDAEISGYAKITVDIGSASQLEAAFNDGNNNWDSNNTKNYSFSTGTSTYTPGNSGNAGTITSGAPAGANPGDGGGTTNKVTVYYKKGFNSPYIHYRPAGGSWTAAPGVKMQDAEISGYAKITVDIGSASQLEAAFNDGNNNWDSNNTKNYLFSTGTSTYTPGSNGAAGTIRTGAPSGSVLSVVTSTYATDLNEVTGPIQTEKLSGVSLNVSTSTYAPNSNGVEVTAQTEAPSGAFTSMDLGTLSNPTSLNTDWSKQSIYFIMTDRFSNGDPSNDNYGGFNSNNSDQRKWHGGDFQGIINKLDYIKNMGFTAIWITPVTMQKSEYAYHGYHTYDFYAVDGHLGTMDKLQELVRKAHDKNIAVMVDVVVNHTGDFQPGNGFAKAPFDKADWYHHNGDITDGDYNSNNQWKIENGDVAGLDDLNHENPATANELKNWIKWLLNETGIDGLRLDTVKHVPKGFLKDFDQAANTFTMGEIFHGDPAYVGDYTRYLDAALDFPMYYTIKDVFGHDQSMRKIKDRYSDDRYYRDAQTNGVFIDNHDVKRFLNDASGKPGANYDKWPQLKAALGFTLTSRGIPIIYQGTEQGYSGGDDPANRENMNFNANHDLYQYIAKLNYVRNNHPALQNGSQREKWVDDSFYSFQRSKNGDEAIVFINNSWNSQTRTIGNFDNLSNGTRLTNQLSNDSVQINNGSITVTLAPKEVKVFTK
What is the function of this protein?
The precursor protein is proteolytically cleaved to produce multiform beta-amylases and a 48 kDa alpha-amylase after secretion.
What are the official names of this protein?
Beta/alpha-amylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.