PharMolix/UniProtQA huggingface dataset:
Protein: CBPC1_DANRE
Sequence: MNKPKMAAEKSASRVLMLLSQLERLNEESRVSDNDAIRQVTGKILHLIQTQEKTRKEVGSKGSGGMEIILSSLENTRDLQTTLNILGILNELLTVGGGRRTGLFVSKGGTAILLQLLVSSSKDPPANEELMLHIHSLLVKVGPKDRKFGVKARLNGALNVTLNLAKHNLQNYKLLLPCLQVLRVYSSNSVNAVSLGKSGALEILFEIVGPFSKKSTTLLKVALDTLAALLKSGMNARRAVDRGYLPTLLAIYQDWHRNDTRHRHVIIRKSILGCIKNITNIKLGRKAFIEASGMRILYNTSTECLPVRTLDPLVNTSSLIMRKCFPKNRLPLPTIKSVFLYPLPHIPAGGPVAQLYNQPPGVDDVVDESDENEATEVDTENDTENEEDDTGHKTQNDDIETDINKLRPKQMNTRPFEELRVYEHFCREFTETFQDIDFEDSISAIPPSRVNSELHRPIIIPTTQSSPGLQNRRPLRESALPLKPEQSPLELDSISIAKRPDGRADADLVCSLGHLILDAAVNGGSVDGCQDDGGEQSVLEVPDTAALLPLHDPELYLEMVKSTRSVPGYTEVAYPDYFGHVALNLREPILERVYGVQRTKIFQDIERLIHSSDILDKVVYDLDNQSSPLTDNGESLKFNSKFESGNLRKAIQVRKFEYDLILNSDINSNHYHQWFYFEVGNMRPGVRYRFNIINCEKSNSQFNYGMQVIMYSVQEAINGSPHWVRTGSDICYYKNHFARSSIAAGGQKGKSYFTMTFTVTFQHKDDVCYFAYHYPYTYSMLKMHLQKLSALCTPEIYYRQEDLCETLGGNGCPLLTITAMPESSSDEHISQFRSRPVIFLSARVHPGETNSSWVMKGSLEFLMSCSPQAQSLRQSYIFKIMPMLNPDGVINGNHRCSLSGEDLNRQWQNPNAELHPTIYHAKSLLQYLRATGRTPLVFCDYHGHSRKKNVFMYGCSIKETMWQSSVNTSTCDLNEDLGYRTLPKLLSQMAPAFSLSSCSFVVERSKEATARVVVWREIGVQRSYTMESTLCGCDQGKYKGLQIGTSELEEMGSQFCLALLRLRRFTSPLELHNHNSHLLDMENELIDTRHIPNITSPTTYVLDEDEPAFLEEVDYSAESNDENDPELEPDLRDNHALPDPSSDSELSHQDSLT
What is the function of this protein?
Metallocarboxypeptidase that mediates protein deglutamylation of tubulin and non-tubulin target proteins.  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of alpha- and beta-tubulin.  Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate.  Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of alpha-tubulin as well as non-tubulin proteins.
What are the official names of this protein?
Cytosolic carboxypeptidase 1, ATP/GTP-binding protein 1, Protein deglutamylase CCP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Nucleus. Mitochondrion.
Protein: PNP_HELAH
Sequence: MDFITINSINKTEEFALKQVAKQATSSLLYRLGKTIILASVCVERELVSEDFLPLVVQFLEKSYAAGKIPGGFVKREGRAQDFEILTSRLIDRTLRPLFPKDYRYPTQITLMVLSHDIENDLQVSALNAASAALFLAHAAPFKSVSACRIARIDNEFIINPSTSLLNQSSLDLFVSGTKESLNMIEMRSLGQKLNALEEPLMLEALELAQKSLKETCTLYEETFTPHQNALLFKESQGIVFNERLLDLLKNQYFNEIIKGIESSALSERENVFNEIARKISEAHSEFNLEEIELSLEKVKKTEIRRMIIRDKIRPDKRALEEVRPISIESNLLPMAHSSILFTRGQTQSLVVGVLGTDNDAQTHESLEHKAPIKERFMFHYNFPPFCVGEASSIGATSRRELGHGNLAKRALETSIKNKDQVIRLVSEILESNGSSSMASVCAGSLALYASGVEIHDLVAGVAMGMVSEGQDYAILSDISGLEDAEGDMDFKIAGNLEGITAMQMDTKMSGIQLEILYQTLLQAKRVREHILKIMHEAKEKIVINFSHLPTTEIFNVAPDKIIEIIGQGGRVIREIVEKFEVKIDLNKPSGEVKIMGNKERVLKTKEFILNYLHSLDQELEQYAIDEVLEAQVKRIVDFGAFLSLPKGGEGLLRKQHMERCQVALKEGDSIRCRVISFNKGKIALDLA
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_PSESM
Sequence: MIQTQSMLDVADNSGARRVMCIKVLGGSHRRYAGIGDIIKVTVKEAIPRGKVKKGQVMTAVVVRTRHGVRRADGSIIRFDGNAAVLLNNKQEPIGTRIFGPVTRELRTEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: HEPA_HCMVA
Sequence: MTAQPPLHHRHHPYTLFGTSCHLSWYGLLEASVPIVQCLFLDLGGGRAEPRLHTFVVRGDRLPPAEVRAVHRASYAALASAVTTDADERRRGLEQRSAVLARVLLEGSALIRVLARTFTPVQIQTDASGVEILEAAPALGVETAALSNALSLFHVAKLVVIGSYPEVHEPRVVTHTAERVSEEYGTHAHKKLRRGYYAYDLAMSFRVGTHKYVLERDDEAVLARLFEVREVCFLRTCLRLVTPVGFVAVAVTDEQCCLLLQSAWTHLYDVLFRGFAGQPPLRDYLGPDLFETGAARSFFFPGFPPVPVYAVHGLHTLMRETALDAAAEVLSWCGLPDIVGSAGKLEVEPCALSLGVPEDEWQVFGTEAGGGAVRLNATAFRERPAGGDRRWLLPPLPRDDGDGENNVVEVSSSTGGAHPPSDDATFTVHVRDATLHRVLIVDLVERVLAKCVRARDFNPYVRYSHRLHTYAVCEKFIENLRFRSRRAFWQIQSLLGYISEHVTSACASAGLLWVLSRGHREFYVYDGYSGHGPVSAEVCVRTVVDCYWRKLFGGDDPGPTCRVQESAPGVLLVWGDERLVGPFNFFYGNGGAGGSPLHGVVGGFAAGHCGGACCAGCVVTHRHSSGGGGSGVGDADHASGGGLDAAAGSGHNGGSDRVSPSTPPAALGGCCCAAGGDWLSAVGHVLGRLPALLRERVSVSELEAVYREILFRFVARRNDVDFWLLRFQPGENEVRPHAGVIDCAPFHGVWAEQGQIIVQSRDTALAADIGYGVYVDKAFAMLTACVEVWARELLSSSTASTTACSSSSVLSSALPSVTSSSSGTATVSPPSCSSSSATWLEERDEWVRSLAVDAQHAAKRVASEGLRFFRLNA
What is the function of this protein?
Component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase synthesizes short RNA primers on the lagging strand that the polymerase presumably elongates using dNTPs.  The primase-associated factor has no known catalytic activity in the complex and may serve to facilitate the formation of the replisome by directly interacting with the origin-binding protein and the polymerase.
What are the official names of this protein?
DNA helicase/primase complex-associated protein, HEPA, Primase-associated factor.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae HEPA family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: SFSA_ECO27
Sequence: MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGCATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAIICVNTLWANRLTKEAILNESISELAGYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKHLRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAELSAEGMALKKSLPVTL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RLMH_GEOSW
Sequence: MHIHIISVGKLKEKYLMQGIDEYKKRLSSYAKVDIIEVPDEKAPEHLSEQEMEQIKQREGERILAKIPNDAYVIALAIEGKMKSSEQFAASLDKLATYGKSKIAFIIGGSLGLSKQVMQRADEALSFSKMTFPHQLMRLILLEQIYRAFRINRGEPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_ECO57
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: URE1_ACIAC
Sequence: MATVSRRAYAEMFGPTVGDRVRLADTGLVAEVEQDFTLRAGGYGEEVKFGGGKTIRDGMAQSQRTRAEGAMDTVLTNALVIDHWGIVKADIGLKDGRVAAIGKAGNPDTQPGVDIVIGPGTEIISCEGNIVTAGGIDSHIHFICPQQIEEALASGITTMLGGGTGPATGTLATTCTPGPWHIERMLQAADAFPMNIGFLGKGNASLPAALHEQIEAGVIGLKLHEDWGTTPSAISNCMDVADATDTQVAIHSDTLNESGFVENTIAAVGGRGICAFHTEGAGGGHAPDILRVVGEDNFLPSSTNPTMPYTRNTLDEHVDMLMVCHHLDAAIAEDLAFAESRIRKETIAAEDILHDLGAISMMSSDSQAMGRVGEVILRTWQTADKMKQQRGALPEDGARNDNHRIKRYVAKYTINPAIAHGISHDVGSLEVGKWADIVVWKPAFFGVKPAMVLKGGSIAVAAMGDPNASIPTPQPVHYRPMFGAFGGSLARSSLTFVSQAAMAAGVRERFGLAKQLSAVRGIRGVRKQHMVHNGYTPRMEIDAQTYTVRADGQLLTCESATRLPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_NITMU
Sequence: MNLQGRTVLVLGLGETGLSMAKWLFRRGALVRAADTRNEPPAMRAFNSLLPQAEVFTGSLAGRAFYGVDLIAISPGLPLSEPLVQQALKEGIPVVGDMELFACAVGGTGGGMPKLVGITGSNGKTTVTAMTGAMLKKAGWDVEVAGNIGPAVLDALMRREDTGKMPQAWVLELSSFQLETTKSLGLDAAAVLNVSEDHLDRYAGMQEYAAAKARIFLGDSEGVQILNGDDPVVRQMTLAGRPHVTFSLATPQSADDFGLLREGGDTWLMQGDTRLMDARELAITGRHNCANALAALALCRALAVPFEPLLQALREFRGLPHRVEKVAAFSGITFYDDSKGTNVGATVAALKGLGQPVVLIAGGDGKAQNFSPLAAPIGEHGRAVVLIGRDAEKIAVAINECGVPLHRAQTMEEAVRKSFQLAREGDAVLMSPACASFDMFDNYVHRAEAFVAAVRSMQAARAGGNSAGVAGRH
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_CHAGB
Sequence: MTPYRDVPPVSSRTHSSNRDRSQSRSRMSHESGSSVSTTSIVFDRISERVAAGDLSEKQPRGDDNEDALKDEPDNDDLETGPFLGNASGNGNSPRHAQKKGPGMDRGMRRALLIAAGLLVSAWVAGLFVYIATKSYKPASATAHDPQATIVRGSGKAVTLDQVMGSFWRPEVRSIQWIAGPEGEDGLLLERDAAGKDYLVVEDIRSQDAAAVDSSADAQAADARTLMEKGSFEYGKRVYNAVKVAPSRDLQRVLVATDVKSNWRHSSYAAYWIFDVKTQTADPLVPGEPDARIQLAQWNPTGDAVAFTRDNNLYLRKVGSDNIIQVTKDGGSEVFNGVPDWVYEEEVFSGSSATWWSEDGDYIAFLRTNETGVPEFPIDYFLKRPSGTEPKPGEEAYPETRKIKYPKAGAHNPVVELKFYDVVRGDVFSVDISGGFADDDRLITEVVWAGKQILVKETNRVSDVMRVVLVDVAARSGKTVRTTDVKAIDGGWFEITHQTKHIPADPSKGREHDGYIDLIIHGDGNHLAYFTPLDNPDPVMLTSGDWEVVDSPYAVDLDKNVVYFMATKESSIQRHVYQVKLTGEDLTAVSDTSSEGYYAASFSIGGGYALLTYQGPGIPWQKVISTPSNPRKYEHTVEENKDLADNAKKHELPIKIYGTINVDGVELNYVERRPAHFDASKKYPVLFQQYSGPGSQTVNKKFTVDFQSYVAAGLGYICVTVDGRGTGYIGRKNRVIVRGNLGQWEAHDQIAAAKIWAKKKYIDETRLAIWGWSFGGFNALKTLEQDAGETFRYGMAVAPVTDWRFYDSIYTERYMLTPQANGHGYDTSAIYNTTALGQNVRFLLMHGLADDNVHFQSSLTLLDKLNLAGVENYDVHVFPDSDHSIYFHNANRIVYDKLTNWLINAFNGEWIKVASPKPNGKRRAA
What is the function of this protein?
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl-aminopeptidase B, DPAP B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.
Protein: AA2AR_CANLF
Sequence: MSTMGSWVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHNCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAVCWVLSFAIGLTPMLGWNNCSQPKEGRNYSQGCGEGQVACLFEDVVPMNYMVYYNFFAFVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPECSHAPLWLMYLTIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRRREPFKAGGTSARALAAHGSDGEQISLRLNGHPPGVWANGSAPHPERRPNGYTLGLVSGGIAPESHGDMGLPDVELLSHELKGACPESPGLEGPLAQDGAGVS
What is the function of this protein?
Receptor for adenosine (PubMed:2125216).  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (PubMed:2125216).
What are the official names of this protein?
Adenosine receptor A2a.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Colocalizes with GAS2L2 at neuronal processes.
Protein: EAA1_AMBTI
Sequence: MTKSNGEDPRAGSRMERFQQGVRQRTLLAKKKVQNITKDDVKGFLKRNGFVLFTVIAVVVGSILGFSVRSYHMTFRELKYFSFPGELLMRMLQMLVLPLIVSSLVTGMAALDSKASGKMGLRAVVYYMTTTVIAVFIGIVIVIIVHPGKGTKEHMHREGKIEPVTAADAFLDLIRNMFPPNMVEACFKQFKTSYEKKIFKVTMPANETAVMTSVLNNVSEAMETLTKMREEMIPVPGAVNGVNALGLVVFSMCFGLVIGNMKEQGKALKDFFDSLNEAIMRLVAVIMWYAPIGILFLIAGKIAEMEDMGVVGGQLGMYTVTVIIGLLIHAVIVLPLLYFAVTRKNPWVFIGGILQALITALGTSSSSATLPITFKCLEENNKVDKRVTRFVLPVGATINMDGTALYEALAAIFIAQVNNYDLNFGQILTISITATAASIGAAGIPQAGLVTMVIVLTSVGLPTDDITLIIAVDWFLDRLRTTTNVLGDSLGAGIVEHLSRHELQSGDAEMGNSVIEENEMKKPYQLVSQENELEKPIDSETKM
What is the function of this protein?
Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:9425012, PubMed:17008380).  Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:17008380).  Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity).
What are the official names of this protein?
Excitatory amino acid transporter 1, SEAAT1, Sodium-dependent glutamate/aspartate transporter, GLAST.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MUTS_STRT1
Sequence: MAKEKISPGMQQYLDIKKNYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLVEMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSANNFLVAIDKVGSRFGLSYMDVSTGEFFATELDDFSSVCSEIQNLKAREVVVGYDLLETDEQVLVNQLNLLLSKETEGYDDVHLIGNSLTDLESSVASKLLQYVHRTQMRELSHLQKAQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDKTKTAMGMRLLRTWIDRPLVNQASIIERQNIIQVFLDNFFERSDLAESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFNDDALSGLLQELDALPELESLIRSAIDPDAPATITEGGIIRDGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKATLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFNDEHRIAIDRGRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVMAQMGAYVPADSVDLPVFDAIYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHELTALSNSLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPTDLLNRADTILTQLEGETVVIQPQEKVLSQEKPAIETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RUB1_ARATH
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGTMIKVKTLTGKEIEIDIEPTDTIDRIKERVEEKEGIPPVQQRLIYAGKQLADDKTAKDYNIEGGSVLHLVLALRGGFGLL
What is the function of this protein?
Appears to function as a stable post-translational protein modifier.  An AMP-RUB1 intermediate is formed by an activating enzyme, distinct from the ubiquitin activating enzyme E1, which is composed of a heterodimer AXR1/ECR1.  Auxin response is mediated, at least in part, through modification of the cullin AtCUL1 by the attachment of RUB1 to 'Lys-692'.
What are the official names of this protein?
Ubiquitin-NEDD8-like protein RUB1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: HOA_VEREI
Sequence: MTLKGKQITVHDMTLRDGMHPKRHLMTLEQMKTIACGLDAAGVPLIEVTHGDGLGGSSVNYGFPAHSDEQYLSAVIPLVKQAKVSALLLPGIGTVDHLKMAHGLGVHTIRVATHCTEADVSEQHIRFARKLEMDTVGFLMMAHMASPEKLLEQAKLMEGYGANCIYVTDSAGHLLPETVKTRVGAVREALKPETELGFHGHHNLAMGVANSIAAIEAGANRIDAAAAGLGAGAGNTPMEVLIAVCDLMGIATGVDVFKIQDVAEDLVVPIMDFPIRIDRDALTLGYAGVYGSFLLFAKRAEQKYGVPARDILVEMGRRGMVGGQEDMIEDTAMTMARERGRLAA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: IE0_NPVAC
Sequence: MIRTSSHVLNVQENIMTSNCASSPYSCEATSACAEAQQVMIDNFVFFHMYNADIQIDAKLQCGVRSAAFAMIDDKHLEMYKHRIENKFFYYYDQCADIAKPDRLPDDDGACCHHFIFDAQRIIQCIKEIESAYGVRDRGNVIVFYPYLKQLRDALKLIKNSFACCFKIINSMQMYVNELISNCLLFIEKLETINKTVKVMNLFVDNLVLYECNVCKEISTDERFLKPKECCEYAICNACCVNMWKTATTHAKCPACRTSYK
What is the function of this protein?
Putative viral E3 ligase that plays an essential regulatory role in both viral DNA replication and transcriptional transactivation.  The role in transcription has been shown to include activation of gene expression from early viral promoters.  Promotes also the efficient egress of nucleocapsids from the host nucleus.  May act as an E3 ligase that promotes ubiquitination of nucleocapsids proteins by vUbi and subsequent viral egress for the host nucleus.
What are the official names of this protein?
Immediate-early protein IE-0, Immediate early 0 protein, Immediate early transactivator 0.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Virion.
Protein: ISPT_STRA5
Sequence: MFIFKRKKQVEMPLEKIPAHIGIIMDGNGRWAKKRLKPRVMGHKAGMDALQEVTIAASGLGVKVLTVYAFSTENWSRPDDEVKFIMNLPVKFFDKYVPELDKNNVRVQVIGDTHKLPKATYDAMQRACLRTKHNSGLVLNFALNYGGRSEITNAIKEIAQDVLEAKLNPDDITEDLVANHLMTNSLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFYFTPVLWPDFKKDELHKAIVDYNQRHRRFGSV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: DLGD_SALPK
Sequence: MKVTFEELKGAFYRVLRSRNIAEDTADACAEMFARTTESGVYSHGVNRFPRFIQQLDNGDIIPDAKPQRVTSLGAIEQWDAQRAIGNLTAKKMMDRAIELASDHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLIVAIPSTPITMVDMSMSMFSYGMLEVNRLAGRELPVDGGFDDNGQLTKEPGVIEKNRRILPMGYWKGSGLSIVLDMIATLLSNGSSVAEVTQENSDEYGVSQIFIAIEVDKLIDGATRDAKLQRIMDFITTAERADDNVAIRLPGHEFTKLLDDNRRHGITVDDSVWAKIQAL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_PSEA8
Sequence: MANNEQKRDEGYIEKLVQVNRVAKTVKGGRIFAFTALTVVGDGKGRVGFGRGKAREVPAAIQKAMEAARRNMIQVDLNGTTLQYPTKSAHGASKVYMQPASEGTGIIAGGAMRAVLEVAGVQNVLAKCYGSTNPVNVVYATFKGLKNMQAPEAVAAKRGKSVEEIL
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CIRBP_LITCT
Sequence: MSCDEGKLFVGGLSFDTDEQCLETVFSKYGQIQEVVVVKDRETKRSRGFGFVTFENCEDAKDAMAGMNGKTVDGRQIRVDQAGKSSNDRRGGYRGGSSGGGRGFFRGGRGRGGGGYGGSSRFDNRSGGGYGGWIPDYYSSGRESSYGDRSAGGRSYRDSYDSYG
What is the function of this protein?
Cold-inducible mRNA binding protein.  Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to them and inhibiting their deadenylation.  Essential for embryonic gastrulation and neural development, acting to maintain the expression of a set of adhesion molecules, and cell movement during embryogenesis.  Required for pronephros development (By similarity).  May play a role in hibernation.
What are the official names of this protein?
Cold-inducible RNA-binding protein, BFCIRP, Glycine-rich RNA-binding protein CIRP.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm. Predominantly cytoplasmic in oocytes. Translocates from the nucleus to the cytoplasm upon arginine methylation (By similarity).
Protein: ALGD_PSESH
Sequence: MRISIFGLGYVGAVCAGCLSARGHDVVGVDISSTKIDLINNGKSPIVEPGLEELLQKGISTGKLRGTTDFAEAIRATDLSMICVGTPSKKNGDLELDYIESVCREIGYVLRDKATRHTIVVRSTVLPGTVANVVIPILEDCSGKKAGVDFGVAVNPEFLRESTAIKDYDLPPMTVIGEFDKASGDVLQSLYEELDAPIIRKDIAVAEMIKYTCNVWHATKVTFANEIGNIAKAVGVDGREVMDVVCQDKALNLSQYYMRPGFAFGGSCLPKDVRALTYRASSLDVEAPLLNSLMRSNTSQVQNAFDMVASYDTRKVALLGLSFKAGTDDLRESPLVELAEMLIGKGFDLSIFDSNVEYARVHGANKDYIESKIPHVSSLLNSDFDQVINDSDVIILGNRDERFRALANKTPEGKRVIDLVGFMTNATSEDGRAEGICW
What is the function of this protein?
Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization.  The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics (By similarity).
What are the official names of this protein?
GDP-mannose 6-dehydrogenase, GMD.
What is the protein family that this protein belongs to?
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
Protein: PSBE_TRICV
Sequence: MSGGSTGERPFSDIITSVRYWIIHSITIPSLFVSGWLFVSTGLAYDVFGTPRPNEYFTQDRQQIPLVNDRFSAKQELEDLTKGL
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PRP5_VANPO
Sequence: MSADNVSSIDPEKERISRERREKLAKWRAKKALMDSQNELKKETVPLEVKNSKITNNENDSTSRSKLLERQHKLQEWKRKKREREEEQLIKEQENTKETSSHSKKKNKKQNRGSQKRQITFDDSDDETTGESKDSFDKSEIVVEKSDMSGSKNNNEDDPLEAYMKSLVNGGQPLNHKIGENILDEDGDDNSIEEDDEFSNSESDEESSRYKRISKAKAKKKVKEIKFTIKDLEPFPKSFYSEPDEVKLMTDDEVEEMRLSLGGIKVKGKHCPKLITRWSQLGLPTDIMNLITKELKYDEPTAIQSQAIPAIMSGRDLIGISKTGSGKTISYILPMLRQIKAQRTLSKNETGPLGLILAPTRELALQINEEVEKFTKQDRSIRTICCTGGSEMKKQINDLKRGVEIVVATPGRLIDILTLNSGKLISTKRITFVVMDEADRLFDMGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAARILTDPLTVTINSNNLVNENVNQSFYIEDNENDKFNRLVNILDGFYKVNKNITSNSEEREIDEEVSDKKIIIFVSSQQFCDLLYSKLENFGYFPYTIHAGKPYQERVMNLEKFKTTTNSILLCTEVLSRGLNVPEVSLVIIYNAAKTFAQYVHTTGRTARGTHKGDAITLLLPDELAAAYILKRALRERELSSIDPQMVEDMKQMSERFESGMKEGKYKLSKGFGGKGLDNLDTKREEKQQEEKHKLDKIENDESTPSTSYKTTDNASSSSEVDSVTIPKLEFTIDRDKNIDSTISFTAIVNVNDLPQLVRWEATKNTTLMFIKHETGCSITNKGKYYPEGKGPTSNKDQPKLYLQIEGKEEKDVLLSIELLEQKVREGIKKVEYQSIKSTKY
What is the function of this protein?
ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing.  Catalyzes an ATP-dependent conformational change of U2 snRNP.  Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-processing ATP-dependent RNA helicase PRP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: 11K_PAVHV
Sequence: MQNNTTGMDTKSLKNCGQPKAVCTHCKHSPPCPQPGCVTKRPPVPPRLYLPPPVPIRQPNTKDIDNVEFKYLTRYEQHVIRMLRLCNMYQNLEK
What is the function of this protein?
Enhances viral DNA replication and virion release (PubMed:29437973).  Plays a role in viral infectivity (PubMed:16731932).  Induces apoptosis of primary erythroid progenitor cells (PubMed:19861680).
What are the official names of this protein?
Host-modulation protein 11K, Host-modulation protein of 11 kDa.
What are the subcellular locations of this protein?
Host cytoplasm.