PharMolix/UniProtQA huggingface dataset:
Protein: THIG_PROM0
Sequence: MKNYSSLIIGGKKFSSRLMVGTGKYKSSQDMVESLSNSETEIITVAVRRIKNEQSGENLLEKINWEKYWMLPNTAGCVNSDEAVRIAILGRELAKLSGQEENNFVKLEVIPDKKYLLPDPIETLKAAEILIKKGFAVLPYINADPILAKRLEEIGCATVMPLGSPIGSGQGLLNLSNIRIIIENAKVPVIIDAGIGVPSEASQAMEIGADGVLINSAIAQAANPPLMAQAINYSVKAGRQAFLAGRIKKQDFAVASSPEKNISI
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOX6_ARATH
Sequence: MFVASPVKTNFNGVSLVKSPAFSALSCRKQHRVPISRQVRAVISREEKAVDQEDGKKSTNKPLINSSQFPWQRSKYTGSKTVTAVVKIRKKIKEKLTERFEHQLELFMKAIGQGMLIQLVSEEIDPETGKGRKSLESPVMGLPKAVKDPRYLVFTADFTVPINFGKPGAILVTNLLSTEICLSEIIIEDSTDTILFPANTWIHSKNDNPQARIIFRSQPCLPSETPDGIKELREKDLVSVRGDGKGERKPHERIYDYDVYNDLGDPRKTERVRPVLGVPETPYPRRCRTGRPLVSKDPPCESRGKEKEEFYVPRDEVFEEIKRDTFRAGRFKALFHNLVPSIAAALSNLDIPFTCFSDIDNLYKSNIVLGHTEPKDTGLGGFIGGFMNGILNVTETLLKYDTPAVIKWDRFAWLRDNEFGRQALAGVNPVNIELLKELPIRSNLDPALYGPQESVLTEEIIAREVEHYGTTIEKALEEKRLFLVDYHDILLPFVEKINSIKEDPRKTYASRTIFFYSKNGALRPLAIELSLPPTAESENKFVYTHGHDATTHWIWKLAKAHVCSNDAGVHQLVNHWLRTHASMEPYIIATNRQLSTMHPVYKLLHPHMRYTLEINARARKSLINGGGIIESCFTPGKYAMELSSAAYKSMWRFDMEGLPADLVRRGMAEEDSSAECGVRLVIDDYPYAADGLLIWKAIKDLVESYVKHFYSDSKSITSDLELQAWWDEIKNKGHYDKKDEPWWPKLNTTQDLSQILTNMIWIASGQHAAINFGQYPFGGYVPNRPTLLRKLIPQETDPDYEMFMRNPQYSFLGSLPTQLQATKVMAVQETLSTHSPDEEYLIELREVQRHWFQDEQVVKYFNKFSEELVKIEKTINERNKDKKLKNRTGAGMPPYELLLPTSPHGVTGRGIPNSISI
What is the function of this protein?
Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).  13S-lipoxygenase that can use linolenic acid as substrates.
What are the official names of this protein?
Lipoxygenase 6, chloroplastic, AtLOX6.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPE_CLOBM
Sequence: MLSKAHAKVNLSLDVIGKRKDGYHLLKMLMQTIDLYDLIQIKKIKKGIIIDCDREYIPKDRRNLAYKAAELFLDRYNIDSGVRIDITKNIPVAAGLAGGSTDAATVLKIMRDIFRSDISNKELKEIALDIGADVPFCIEGGTALCEGIGEKITPIKNFKNQILVLVKPNFGLSTKDVYNNLKVEKIYIHPNTTKLIQSIEEDNLKSVARNMRNVLENVTLRKYKTLNSIKSNFIELGALGSMMSGSGPSVFGLFDDMLKAQICYDNMKEKYKEVFITRTI
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PURT_ACIBT
Sequence: MSVTLGTPLQSSAFKVLLLGSGELGKEVVISLQRLGVEVHAADRYDHAPAMQVAHFSYVLNMADPAQLKQLIEKVKPNLIVPEIEAIATEVLLEIEANKTATVIPSAKAVNLTMNREGIRRLAAEELGLPTSAYRFADTLESFRAACDDIGYPNFVKPVMSSSGKGQSRVKSFDEVDAAWEYAMQGGRVNQGTVIIESQIDFDFEITLLTVRAKNPETGEIETHYCDPIGHRQDAGDYVESWQPQPMTPAALEEAKRIANKVTTALGGCGIFGVELFIKGDKVWFSEVSPRPHDTGLVTLASQFQSEFELHARAILGLPVNTARHSVAASAVIYAGVDANNLSYSNLNVALAHPDTDLRLFGKPEGFKRRRMGVATARAENTDLARTLAKETADQVSVQTNS
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: ILVC_YERPP
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADEAGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVAYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSAVVKAVQPLMKEGAALGYSHGFNIVEVGEQVRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLEFSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVSEGTDAAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGAFSSGMMADWANDDVKLLNWREETGRTAFENAPQFEGKISEQEYFDHGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKEKFMDSLQAGDLGKSIPGSAVDNAQLRDVNEAIRNHPIEAVGHKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: COA3_YARLI
Sequence: MSQDPHNGKGTFEVHKQPQPGLKVFRKGKYIDPKTFQMSPALIRARRPFFVRNMLALAGLTGFVAGIYGYTMYSLRTDDFGDVPIPPLDPEEIKKLQSKYSDDSKA
What is the function of this protein?
Required for assembly of cytochrome c oxidase (complex IV).
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: TIM13_SCHPO
Sequence: MGIFGGNSGNAPSSEDKKSIFMKQIRQELAVAQAGELISKINENCFDKCIPEPGSTFDPNEKSCVSKCMERYMDAWNIVSRTYISRMQREQKNLN
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: CIB2_MOUSE
Sequence: MGNKQTIFTEEQLDNYQDCTFFNKKDILKLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRELKANYAFKIYDFNTDNFICKEDLEMTLARLTKSELEEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
What is the function of this protein?
Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis (PubMed:23023331, PubMed:29084757, PubMed:29255404, PubMed:28663585, PubMed:34089643).  Acts as a auxiliary subunit of the sensory mechanoelectrical transduction (MET) channel in hair cells (PubMed:34089643).  Essential for mechanoelectrical transduction (MET) currents in auditory hair cells and thereby required for hearing (PubMed:29084757, PubMed:29255404, PubMed:28663585).  Regulates the function of hair cell mechanotransduction by controlling the distribution of transmembrane channel-like proteins TMC1 and TMC2, and by regulating the function of the MET channels in hair cells (PubMed:34089643).  Required for the maintenance of auditory hair cell stereocilia bundle morphology and function and for hair-cell survival in the cochlea (PubMed:29084757, PubMed:29255404, PubMed:28663585).  Critical for proper photoreceptor cell maintenance and function (PubMed:23023331).  Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (PubMed:23023331).  Seems to be dispensable for vestibular functions (PubMed:29084757).
What are the official names of this protein?
Calcium and integrin-binding family member 2, Kinase-interacting protein 2, KIP 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, stereocilium. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cell membrane, sarcolemma. Note=Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ) (PubMed:18611855). Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells (By similarity).
Protein: ILVD_SALDC
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDSDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIKLDLVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNCNVKNVLGLTLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFSQDCRWDSLDDDRAAGCIRSLEYAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGTIALIEDGDTIAIDIPNRSIQLQLNEAEIAARREAQEARGDKAWTPKNRQRQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PSBM_VITVI
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQNN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HFQ_VIBVY
Sequence: MAKGQSLQDPFLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARPVSHHSGERGSDRPSEKSED
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: NAGB_CORK4
Sequence: MEIVIRKTPEQVSLQAADILEPYVSEGATLGLATGSTPLGTYQELIRRHNESGLSFANNQAFLLDEYVGLPRDHEQSYYRTIRREFTEHIDIKDEAVSSPDGLADNIDEAGRAYDERIRNAGGVDIQILGIGTDGHIGFNEPGSSLNSPTRLKTLHPQTVSDNARFFDSEDDVPRHVLTQGLGTIQHARHLLLLATGKNKAAAVQALAEGPVSASCPASVLQLHPHATVIIDEAAATCLEHKEYYIFAEKNKPEWQRY
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: DDX6_XENTR
Sequence: MSTARTENPVLMGMSSQNGQLRGPLKPSAGPGGGGTQTQQINQLKNASTINSGSQQQAQSMSSVIKPGDDWKKTLKLPPKDLRIKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLERLDLKKDCIQAMVIVPTRELALQVSQICIQVSKHMGGVKVMATTGGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVAKVDHIQMIVLDEADKLLSQDFVQIMEDIIITLPKNRQILLYSATFPLSVQKFMTSHLQKPYEINLMEELTLKGVTQYYAYVTERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGTEIKPIPSSIDKSLYVAEYHSESGEDKP
What is the function of this protein?
ATP-dependent RNA helicase that is an integral component of messenger ribonucleoprotein complexes (mRNPs), storage particles that mask maternal mRNAs from the translational apparatus during oocyte maturation.
What are the official names of this protein?
Probable ATP-dependent RNA helicase ddx6, DEAD box protein 6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm. Nucleus. Note=Mostly cytoplasmic. Upon cellular stress, relocalizes to stress granules.
Protein: SECA_BACC4
Sequence: MIGILKKVFDVNQRQIKRMQKTVEQIDALESSIKPLTDEQLKGKTLEFKERLTKGETVDDLLPEAFAVVREAATRVLGMRPYGVQLMGGIALHEGNISEMKTGEGKTLTSTLPVYLNALTGKGVHVVTVNEYLAQRDASEMGQLHEFLGLTVGINLNSMSREEKQEAYAADITYSTNNELGFDYLRDNMVLYKEQCVQRPLHFAIIDEVDSILVDEARTPLIISGQAQKSTELYMFANAFVRTLENEKDYSFDVKTKNVMLTEDGITKAEKAFHIENLFDLKHVALLHHINQGLRAHVVMHRDTDYVVQEGEIVIVDQFTGRLMKGRRYSEGLHQAIEAKEGVEIQNESMTLATITFQNYFRMYEKLSGMTGTAKTEEEEFRNIYNMNVIVIPTNKPIIRDDRADLIFKSMEGKFNAVVEDIVNRHKKGQPVLVGTVAIETSELISKMLTRKGVRHNILNAKNHAREADIIAEAGIKGAVTIATNMAGRGTDIKLGDDVKNVGLAVIGTERHESRRIDNQLRGRAGRQGDPGVTQFYLSMEDELMRRFGSDNMKAMMDRLGMDDSQPIESKMVSRAVESAQKRVEGNNYDARKQLLQYDDVLRQQREVIYKQRQEVMESDNLRGIIEGMMKSTVERAVALHTQEEIEEDWNIKGLVDYLNTNLLQDGDVKEEELRRLAPEEMSEPIIAKLIERYNEKEKLMPEEQMREFEKVVVFRVVDTKWTEHIDAMDHLREGIHLRAYGQIDPLREYQMEGFAMFESMVASIEEEISRYIMKAEIEQNLERQEVVQGEAVHPSSDGEEAKKKPVVKGDQVGRNDLCKCGSGKKYKNCCGIVQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: DAPF_ZYMMO
Sequence: MTFSFHKMHGLGNDFIVLDARKNPIQMNPALAQALSNRHTGIGCDQLIIIGNGKNQADVSMEIWNADGSEVEACGNATRCVPVFLGRDVIISTAAGLLDARLSDEGACVDMGRPRLSWDEIPLAYAMDTLSMPVAWEDLKEPTAVNMGNPHVVFVVDDVDAVDFGRLGNMIEHDQLFPERINVNIVMVTGKDHLKMRTWERGAGLTRACGTGACATFVAAKRRRLVSGKTQIDLPGGRLVLDENSEGHIIMRGPATYVFKGEADWASFS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_RUMCH
Sequence: MRKIRLTIEYDGTNYHGWQIQKNAKTVQEVIQKALSKLLGEDVGVTGCSRTDVGVHAYGQVAHFLTDSKIPGDKFSYAINNLLPDDIVIKNSEEVPEEFHARYSAKGKKYRYLIYNSPHASAIMRNRSCHVRPELNVAEMQKAAGYFKGEHDFLAFQATGGQVRSTVREIYGMEVYVKEDNMISIEVSGNGFLYNMVRIIAGTLIYVGMGKLHESEIPGIIAGLDRTKAGKTAPAQGLYLVQIYY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: H2A_ASPCL
Sequence: MTGGKSGGKASGSKNAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTPKSGKGPSQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS14_XYLFA
Sequence: MAKISMINRDLKRKRLAKKFADKRLSLKKVISSDASSYEEKIEASCKLQKLPRDSSPTRLRNRCEISGRPRGVYCKFGLGRNKLREAAMRGDVPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: OBG_BAUCH
Sequence: MKFIDEATIIVAAGDGGNGCISFRREKYIPFGPAEGGDGGNGGNVWLQADENLNTLIDYHFQHNFHAENGKHGQGKNFTGKCGKDLTIKVPIGTRVVDQNTNEILGDLIVHQQYLLVAKGGLRGLGNNHFKSSANCTPRKKTNGTKGEIRRLQLELILLADVGLLGLPNVGKSTLIRAVSAAKPKVANYPFTTLVPNLGVVQVHKKQSFIIADIPGLIKGAADGAGLGIRFLKHLERCRILLHLIDLAPADQSSPVENASIIINELKRYSEKLATKPSWLVFNKLDLIDKREALNIAQTISDALNQKHNYYLISAMNHQGIKTLCRDIMLFINKNK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH_PROM3
Sequence: MDTQAFKRSLHHSERYNRRGFGRANEVASNLEKAYQSSLIGSIRDNGYVLQHGRLQVKLAEAFGFCWGVERAVAMAYETRRHYPSERIWITNEIIHNPSVNEHLREMDVLFIHAEGGVKDFSCVSDGDVVILPAFGATVQEMELLHERGCHIIDTTCPWVSKVWHTVEKHKKQEFTSIIHGKVKHEETLATSSFAGTYLVVLDLDEAQLVADYILGQGDRAAFMKRFAKACSANFDPDQDLQRLGVANQTTMLKSETEEIGRLFERTMLRKYGPIELNKHFLSFNTICDATEERQQAMFSLVDEPLDLLVVIGGFNSSNTTHLQEIAISRGIRSFHIDTPERIGDNNSIQHKPLGEDLFIESNFLPAGSVNVGITSGASTPDRVVEHVIQKLIDLTSD
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: Y322_MYCGE
Sequence: MVKLTTWLKKIGWGETITQRIFCFYIYCILFGSLLLFLPIALQDNYQKVVSYGIDWQGKRFEQKTDYNFLDALFLSTSAFSDTGLSTVVVSKTYSIFGQIVLAVLLQLGGIGFVVIAFLAWRLFNFHKKEQYSFYEKLMLQSERGGSKLGNTSEMILVSIIFLFIVELIYGFLYGILFYFIPGFEPANLFADHAKVSTQLKALVVDSNQTIAAFNDINKAFQAGFFHSLSAVNNAGIDLIGGSSFVPYRNGLGIIIQWLTISQIIFGGIGYPCLFDGFEAIKKKIKYGRHTKHQFSLFTKLTVITNIVVILLFFTLLLMVEFIASDSLTNTIVNFSDEKKSLINTQLQSQSNQAIHASVFGNNPNASRVMQLFFMVISSRSAGFSVFPVASEIQTTKIIIALAMFIGASPSSTAGGIRTTTLAVIFLALVAKFKGQKEVKAFKRSIDQTTVIDAFLVLIISLIAVLLTAVLLPLSMEQPVSFIDALFETTSAFGTVGLSSGATVNIALDPNRNTFNFLALCLLMVMGQVGVSSSVLTFVRKHPKANSYSYPKEAVKIG
What are the official names of this protein?
Uncharacterized cation transporter MG322.
What is the protein family that this protein belongs to?
Belongs to the TrkH potassium transport family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HLYA_PROMI
Sequence: MKSKNFKLSPSGRLAASLAIIFVSLNAYGNGIVPDAGHQGPDVSAVNGGTQVINIVTPNNEGISHNQYQDFNVGKPGAVFNNALEAGQSQLAGHLNANSNLNGQAASLILNEVVSRNPSFLLGQQEVFGIAAEYVLSNPNGITCDGCGFINTSRSSLVVGNPLFENGQLKGYSTLNNTNLLSLGKNGLNTTGLLDLIAPRIDSRGKITAAEISAFTGQNTFSQHFDILSSQKPVSALDSYFFGSMQSGRIRIINTAEGSGVKLAGKFTADNDLSVKADNIQTDSQVRYDSYDKDGSENYQNYRGGITVNNSGSSQTLTKTELKGKNITLVASSHNQIKASDLMGDDITLQGADLTIDGKQLQQKETDIDNRWFYSWKYDVTKEKEQIQQIGSQIDAKNNATLTATKGDVTLDAAKINAGNNLAINANKDIHINGLVEKESRSENGNKRNHTSRLESGSWSNSHQTETLKASELTAGKDLGLDAQGSITAQGAKLHANENVLVNAKDNINLNVQKTNNDKTVTDNHVMWGGIGGGQNKNNNNQQQVSHATQLTADGQLLLAADNNVNITGSQVKGNQGAFVKTTQGDVVIDNALSETISKIDERTGTAFNITKSSHKNETNKQTSTGSELISDAQLTVVSGNDVNVIGSLIKSADKLGIHSLGDINVKSAQQVTKIDDEKTSLAITGHAKEVEDKQYSAGFHITHTTNKNTSTETEQANSTISGANVDLQANKDVTFAGSDLKTTAGNASITGDNVAFVSTENKKQTDNTDTTISGGFSYTGGVDKVGSKADFQYDKQHTQTEVTKNRGSQTEVAGDLTITANKDLLHEGASHHVEGRYQESGENIQHLAVNDSETSKTDSLNVGIDVGVNLDYSGVTKPVKKAIEDGVNTTKPGNNTDLTKKVTARDAIANLANLSNLETPNVGVEVGIKGGGSQQSQTDSQAVSTSINAGKIDIDSNNKLHDQGTHYQSTQEGISLTANTHTSEATLDKHQTTFHETKGGGQIGVSTKTGSDITVAIKGEGQTTDNALMETKAKGSQFTSNGDISINVGENAHYEGAQFDAQKGKTVINAGGDLTLAQATDTHSESQSNVNGSANLKVGTTPESKDYGGGFNAGTTHHSKEQTTAKVGTITGSQGIELNAGHNLTLQGTHLSSEQDIALNATNKVDLQSASSEHTEKGNNLSGGVQAGFGKKMTDDASSVNGLGSAQFAIGKQDEKSVSREGGTINNSGNLTINGNSVHLQGAQVNSKDTQLTSQSGDIEITSAQSTDYKNNWGTDIGFNGKKTNNTPKEVTEEKPATSIHNIGGKLLVNVEDQQKTSHQNATLETGTLTINSNKDLTLSGANVTADSVTGNVGGSLNIASQKESDRHVTVGVNVGYNHTNDPKSSQVNKTAKAGGSLLEKTIKDTIDSGIKSSTDAISDKYNSLSSTIADKTGISDETKAKIDQGFGKVGNGIKNIVTGAEGHTANADIKVTHVDNDAVTKTTSLTSNNDLSLNVNGSTKLTGAEIVSQQGQVDLGGSSVKLENIEGHHYEAGADLDLKSSVVDLAKQLVGGDISFKSPVKTNETVNTKASISEK
What is the function of this protein?
Cell-bound hemolysin, which releases heme-iron from erythrocytes by interaction with the erythrocyte membrane.  HpmA requires HpmB function.
What are the official names of this protein?
Hemolysin.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: BBP_CANAL
Sequence: MSNRGRQPSGPPPSRKRETKWSGKPKRYANFGAQSFDTVITGHLTQEQLDAYQRYFRIEEISNFLSVAKQQHKSIVDVLPSAKVDETDHYKRDPSPPPKYDKNGNRTNTRERRVTEALEKERHELVELAASSIKNYMIPSNYRRPSRTVERLYVPVKDYPDINFVGFLIGPRGNTLKKLQEDSGARLQIRGKGSVKEGKSSDGFGSSQTGTDIQDDLHVLITADSPLKISKAVKLVNEIIDKLIFSPQGMNFMKRDQLKELAVLNGTLRETKPFDPEAHEKKQQQQMDITKIVCKICGNIGHIARDCKQNNGKRPLDDNAENEPTTINKKARTDVPPPPPPPPPPAPPSSSTEISKQVPPPPPPPPPPAPSAAASGFATTENYKQGLVPPPPPPPPPPPPPVRSALVNFENNSKVLLTKEKEESGSSELKNTGESSSSSSGVPPSPPPPSSNVPR
What is the function of this protein?
Necessary for the splicing of pre-mRNA.  Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns (By similarity).
What are the official names of this protein?
Branchpoint-bridging protein.
What is the protein family that this protein belongs to?
Belongs to the BBP/SF1 family.
What are the subcellular locations of this protein?
Nucleus.