PharMolix/UniProtQA huggingface dataset:
Protein: BAX_BOVIN
Sequence: MDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGETPELGLEQVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAAEMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQTVTIFVAGVLTASLTIWKKMG
What is the function of this protein?
Plays a role in the mitochondrial apoptotic process.  Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM).  Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis.  Promotes activation of CASP3, and thereby apoptosis.
What are the official names of this protein?
Apoptosis regulator BAX.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
[Isoform Alpha]: Mitochondrion outer membrane; Single-pass membrane protein. Cytoplasm. Note=Colocalizes with 14-3-3 proteins in the cytoplasm. Under stress conditions, undergoes a conformation change that causes release from JNK-phosphorylated 14-3-3 proteins and translocation to the mitochondrion membrane (By similarity). SUBCELLULAR LOCATION: [Isoform Beta]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform Gamma]: Cytoplasm.
Protein: METN_BORPE
Sequence: MIHIENLSKTYATPHGRFEALRGINLHIQQGEVFGIIGPSGAGKSTLVQCINLLERPDQGSIAIGGQALVGLGEAQLRNQRRRIGMVFQGFNLLARRTVYGNVALPLEIAGVARAEIPARVERLLALVGLEHLRDRYPSQISGGQKQRVGIARALANDPDVLLSDEATSALDPETTHNILALLRDINRKTGVTVVMITHQMEVVREICDRVAVLSHGEVVELGSTREVFAAPRHEVTRAMVSAATASDLSEATLAAVKQRIDALAAAEPGRAVRLWRLSLKGVAAGEPLWSDLAREFALDVSLVQARVEDIQGVAVGTLFVLAQGAPHAVKDALAALAAREITVEEIAHEPATDRSAYHVAA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: G6PI_CLOD6
Sequence: MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTFLGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNGLKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKDYLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQLHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENCKRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYNFGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MARCS_MOUSE
Sequence: MGAQFSKTAAKGEATAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAEPGAKEELQANGSAPAADKEEPASGSAATPAAAEKDEAAAATEPGAGAADKEAAEAEPAEPSSPAAEAEGASASSTSSPKAEDGAAPSPSSETPKKKKKRFSFKKSFKLSGFSFKKSKKESGEGAEAEGATAEGAKDEAAAAAGGEGAAAPGEQAGGAGAEGAAGGEPREAEAAEPEQPEQPEQPAAEEPQAEEQSEAAGEKAEEPAPGATAGDASSAAGPEQEAPAATDEAAASAAPAASPEPQPECSPEAPPAPTAE
What is the function of this protein?
MARCKS is the most prominent cellular substrate for protein kinase C.  This protein binds calmodulin, actin, and synapsin.  MARCKS is a filamentous (F) actin cross-linking protein.
What are the official names of this protein?
Myristoylated alanine-rich C-kinase substrate, MARCKS.
What is the protein family that this protein belongs to?
Belongs to the MARCKS family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Membrane; Lipid-anchor.
Protein: SLYA_YEREN
Sequence: MESTLGSDLARLVRVWRALIDHRLKPLELTQTHWVTLHNINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISPDEIELLSGLIDKLERNIIQLQSK
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.  Required for expression of the virulence gene inv.  Important for the regulation of genes that influence the early stages of infection that occur in the Peyer plaque.
What are the official names of this protein?
Transcriptional regulator SlyA, Regulator of virulence protein A.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: NFYA8_ARATH
Sequence: MDKKVSFTSSVAHSTPPYLSTSISWGLPTKSNGVTESLSLKVVDARPERLINTKNISFQDQDSSSTLSSAQSSNDVTSSGDDNPSRQISFLAHSDVCKGFEETQRKRFAIKSGSSTAGIADIHSSPSKANFSFHYADPHFGGLMPAAYLPQATIWNPQMTRVPLPFDLIENEPVFVNAKQFHAIMRRRQQRAKLEAQNKLIKARKPYLHESRHVHALKRPRGSGGRFLNTKKLQESTDPKQDMPIQQQHATGNMSRFVLYQLQNSNDCDCSTTSRSDITSASDSVNLFGHSEFLISDCPSQTNPTMYVHGQSNDMHGGRNTHHFSVHI
What is the function of this protein?
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters.
What are the official names of this protein?
Nuclear transcription factor Y subunit A-8, AtNF-YA-8.
What is the protein family that this protein belongs to?
Belongs to the NFYA/HAP2 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECB_PSYCK
Sequence: MAEEQAQPQLALERIYVKDMSLEVPGAGVFTKEWNPELDINLSSNAEKLDDDHYQVVLTVSVTAKNAEEAAFIAEVHQAGIFLLKDIPEDQIGQILGAYCPNVLFPYAREVISDIVTRGSFPQLLLAPVNFDQAFAQSQQQAQVDAEGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI2_STUS1
Sequence: MSKQSLVSRKNDHLDIVLDPTRAIAATGTGFGAFRFEHCALPELHLDQIDLQTALFGRRLRAPLLISSMTGGAARSAAINAHLAEAAQQLGIAMAVGSQRVALETAGDQGLTGQLRQLAPDILLLANFGAAQLVRGYGVDEARRAVEMIEGDALIVHLNPLQEAVQTGGDRDWRGVLQAIEALAARLPVPVVIKEVGAGISAAVARRLVDAGVAAIDVAGAGGTSWAAVEAARAADASQQAIAEAFADWGIPTAQALLAVRDACPNTPLIASGGIRDGVEAAKAICLGADLVGQAAGVLQAAMHSSEAVVSHFEVLIEQLRIACFCTGSADLAGLRQARLLQLSAC
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
Protein: UVRC_HYDCU
Sequence: MPNQFETQFDIDAFLKHLTERPGVYLMYDASGQIIYVGKAKNLKRRVSSYFKKRHEEIKTETLVSQVASIEVTVTDTESEALILENTLIKRHKPRYNILFRDDKSYPYIFVSTGKKFPSLSYHRGAKRKVGRYFGPFPNASAVHQTLHALQKIFPVRQCTESVFNHRSRPCLQYQIKRCSGPCVEGLVTEAEYNEDVQHTIAFLEGKSFDVIESLGHKMQQASDEFEFEKAALYRDKISALRAIQSQHLINQPGSKDTDVVALAEEANQVCVSIMMYRGGNLWGSQNYFPKIGGQSINPGEIISAFITQHYIDLPIPQMILVSDVLEDKSSLETWLSEQKKAKVSIRKAVSQTHKGLMKLALTNAQSGLKQQLTQKASQAERVKSLQDVLALASPPNHMECFDISHTQGNQTVASCVVFNEGVPNTSAYRKFNIEGIQPGDDYAAMHQAITRRYSRVKKEGLPLPDLIVIDGGKGQLNKAIDVFKTLELDNLPLVSVAKGEGRKAGLEILYTPFNEEGIDLEADDIALHLLNYIRDEAHRFAITSHRSRRQKAQTHSRLEDIPGVGAKTRHKLLTHFGGLTEVKNAAVSELQKVPGISARIAQTIYDFFHGEI
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_SULDN
Sequence: MARISGVDLPKKKRIEYGLTYVYGIGLHASRKILDATGIDYNKRVYELNEDDIAAITKEIRASHVVEGDLRKQVAMDIKALMDLGSYRGLRHRRGLPCRGQKTKTNARTRKGKRKTVGAA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y482_BURTA
Sequence: MRIVLITGISGSGKSVALNALEDAGYYCVDNLPPHVLPELARHLANEGQNRLAVAIDARSSASLDEMPGLIRALSREHDVRVLFLNASTQSLIQRFSETRRRHPLSGSPSHDADVGLLVSLEEAIERERDLVAPLAEFGHQIDTSNLRANVLRTWVKRFIEQKNDDLVLMFESFGFKRGVPLDADFMFDVRALPNPYYDHELRPLTGLDQPVVAFLDALPVVHQMLGDIESFLIKWLPHFREDNRSYLTVAIGCTGGQHRSVFLAETLAARLSRQANVIVRHRDAPVAVDASSRLVT
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein BTH_I0482.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: FETP_ECO57
Sequence: MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: SP5G_STAA2
Sequence: MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: SYK_PARPJ
Sequence: MTEPTQPNAAQPDAARPNVAPEMDDNKIMTERREKLRELREQGVAYPNDFRPTHHAEDLQSQYEQSDKEALEANPLEVAIAGRMMLKRVMGKASFATVRDGSGQIQFFITPTDVGQETYDAFKKWDMGDIVAARGVLFRTNKGELSVRCTELRLLSKSLRPLPDKFHGLADQEMKYRQRYVDLIVTPETRKTFVARTKAISSIRKFMAEADFMEVETPMLHPIPGGAAAKPFTTHHNALDMQMFLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSVRHNPEFTMIEFYAAYTDYKWLMDFTEQLIRQAAIDALGTATITYQGRELDLAKPFHRLTITQAIQKYAPQYTNEQLADSAFLRTELKKFGVDASQPQFLNAGVGSLQLALFEETAESQLWEPTYIIDYPIEVSPLARASDKVAGITERFELFITGREIANGFSELNDPEDQAARFKKQVDQKEAGDEEAMFYDADYIRALEYGMPPAGGCGIGIDRLVMMLTDSPSIRDVILFPHLRRED
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_META3
Sequence: MPLNLNCYLLNLKIDGVMKKYPEDFIVEEITPEGIVLEAGKDIGFKEENKHDWNGSFIHFTMEKINWNTMDAIRELARRTKTKRKNFGFAGTKDKFALTTQRVGCFGIKPEKLEEIKNSIKDITIRDIQKTNIKLRMGHLWGNKFTIKIRLNETDKYYNDISKYEEILKNKNLDYILNYYGTQRFGTFRPITHIVGKFIYNRDFESAFYTYCGAPINETGVVKEAREMVDNGEFEKALKLFPKKSYYNEIKMIRHYIKTGNYKECFKVLPPQLSSMFVNAYQSYLFNEMINIRHRDYSFDILDGDVVEEGAPTGNILGSDTILSDGIQGDIEKYIIEKENLDLKKFKIEDYGNFPGTRRKLITKIYDFESSIDKDNNIISISFKMERGNYATVVLREIISEI
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RS18_AQUAE
Sequence: MVVRAPKKKVCMYCEQKREPDYKNYEELRNFLTERGRIKDRKQTGLCAKHQRRLAVQIKRARQLGLLPYVVY
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CYC_ALLPO
Sequence: ATFSZAPPGBZKAGQKIFKLKCAQCHTVEKGAGHKQGPNLNGLFGRQSGTAAGYSYSAANKNMAVVWZZBTLYDYLLNPKKYIPGTKMVFPGLKKPQDRADLIAYLKESTA
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: Y751_ACTP7
Sequence: MADVKKQSFQDMLDYVHLYRLKNKLHRETADNDRKIRDNQKRVLLLDNLNQYINDSMTVEDIRAIIANMRDDYENRVDDYMIRNAELSKQRREIRQKMAAHKTAASEKNEK
What are the official names of this protein?
UPF0265 protein APP7_0751.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: GATB_LACLM
Sequence: MNFETVIGLEVHVELSTNSKIFSPASTKFGGDPNSNTNVIDWSLPGVLPVMNKGVIDSGIKAALALNMDIHKSMHFDRKNYFYPDNPKAYQISQFDEPIGYNGSIEIELEDGHKATIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRTPEEAYAYLTALKEAILYTGISDVKMEEGSMRCDANVSLRPYGQEAFGVKTEVKNMNSFSNVKKALDFEVARQAKILRAGGEIRQETRRFNDKTGETILMRVKEGASDYRYFPEPDVPRFEISDEWIEQMRASLPMTATARRAHYINDLGLSDYDARQLTATKEVSDFFDQAIKFDTDPKLVSNWLQGEVAQYLNSEKKELHEIGLTPENLTEMIRLISDGTISSKIAKKVFIELAKNGGSAEEFVKKAGLVQISDPDLLLPIIHEVFAKNEQSVADYRGGKQNAAKALVGQLMKATKGQANPTVAQKLLYQELDNF
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: GLNA1_VITVI
Sequence: MALLSDLINLNLSETTEKVIVEYIWVGGSGMDLRSKARTLSGPVSDPAKLPKWNYDGSSTGQAPGEDSEVILYPQAIFKDPFRRGNNILVMCDTYTPAGEPIPTNKRCNAAKIFSHPDVAAEVPWYGIEQEYTLLQKEVKWPIGWPVGGFPGPQGPYYCGIGADKAWGRDIVDAHYKACLYAGINISGINGEVMPGQWEYQVGPSVGISAGDELWVSRYILERITEIAGVVLSFDPKPIQGDWNGAGAHTNYSTKSMRNDGGFEVIKKAIEKLGLRHKEHIAAYGEGNERRLTGRHETADINTFLWGVANRGASIRVGRDTEKAGKGYFEDRRPASNMDPYVVTSMIAETTILWKP
What are the official names of this protein?
Glutamine synthetase cytosolic isozyme 1, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_CHLTR
Sequence: MGAVSRDDYIALCTELVEHDRRYYVLNQPTISDYSYDVKMRELQEIEVQHPEWKVSWSPTMYLGDRPSGQFPVVPHSSPMLSIANVYSLQELEEFFSRTEKLLGYSPGYSLELKIDGIAVAIRYEKRLFAQALSRGNGVKGEDITANVSTIRSLPMRLPQEAPEDLEVRGEVFLSYEAFEELNACQREQGKLEFANPRNAAGGTLKLLSSKEAAKRKLDLSVYGLITDQKKRSHFENLQLCSQWGFFVAGMPKQCRSRQDVVERIREIEEMRAALPMAIDGVVIKVDNIAYQDRLGLTSKHYRWAIAYKYAPERAETILEDIVVQVGKTGILTPVAELAPVFLSGSRVSRASLYNQDEIEKKDIRIGDSVYVEKGGEVIPKIVGINLAKRSLESEPWKMPSLCPVCHEPVVKEKVSVRCVNPLCSGGMLEKICFFASKSALNIDHLGEKVVTKLFEVGLISSCSDIFALAEEDLKQVPGFKDRSIQNLLASIAGAKKVALDRLLTALSIPFVGSSGAIALADHFGTLDKVIEASLDELMSIEGIGPKVAASIVAFFSKHENREEIRRMQELGVQVLSKQSDKEAPLQGKVFVLTGTLQQMTRTQAEERIRCLGGKVSSSVSKSTYAVIAGSEAGGKLKKAQDLGLSIWNESELLRILDAKSVS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MZRA_ERWBE
Sequence: MLALLRPYLSTRVLCVLVVCFSALMLVAFIPTLFRNDTALQIRASRQGTTLPDGFYVYQRLNAEGIRIKSITPDNDSLVIRFDTEEQSMAAEKVLHQLLPYGFDIGQMDPSGSSQLMNRLSLRKQSVG
What is the function of this protein?
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
What are the official names of this protein?
Modulator protein MzrA.
What is the protein family that this protein belongs to?
Belongs to the MzrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NREC_STAAT
Sequence: MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTTDPFKILSKRELEILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
What are the official names of this protein?
Oxygen regulatory protein NreC, Nitrogen regulation protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_HELPH
Sequence: MKDSFLFTSESVTEGHPDKMADQISDAVLDYIIERDQKAKVACETLVSNGFCMITGELKTSVYAPMQEIAREVVKKIGYTDALYGFDYRSAAVLNGIGEQSPDINQGVDREDGEIGAGDQGLMFGYACKETETLMPLPIHLAHQLAFALAQKRKDNTLPFLRPDGKSQVSVHYENNKPVSIDTIVISTQHSPEVSQKHLKEAVIEEIVYKVLPKEYLHDNIKFFVNPTGKFVIGGPQGDAGLTGRKIIVDTYGGSCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKATVQLAYAIGVIEPVSIYVNTHNTSKYSSVELEKCVKAVFKLTPKGIIESLDLLRPIYSLTSAYGHFGRELEEFTWEKTNKDEEIKAFFKR
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBT_DESHY
Sequence: MNMGVDKKQNTVLYISSAIALLFVLWGVFLPENMANVVNKVFALLTTNFGWLYLLAVAIFIIFVFGIAISRYGKIKLGADDDKPEFSNFQWFAMLFGGGMGIGLVFWSVAEPIMHFNSPPFGEPGTVEAMQTSMRVVFFHWGIHAWVNFAIAGLALAYFQFRKGLPFLISSAFYPLIGDRIYGPIGKAIDILAVFATIFGIATSLGLGSSQIATGIQYIWGIPAGPLTISLVIAVITVIFTLATVSGLHKAMQSIANVKVWLSVAFMVFIFYFGGKVFILNTFTQSLGDYLQNFVGQTFWMANESWVGGWTIFYWAWWIAWAPFVGQFVARVSKGRTIREFVFAVTLLPVGFSFIWLAIYGGAAFNLDQISGGFIQNAVNADYTTALFALLQQMPLYAITGPLAILLIVTCFVGAADSATYVLAMLTSNGDMDPSKKLRSFWGIMQGAMTIVLIVVGGTAALKALQTASIASAFPFMLIMLVMCYSILKALRSDHP
What is the function of this protein?
Probably acts in the uptake of glycine betaine.  May function in the pathway that allows anaerobic methylotrophic growth of D. hafniense using glycine betaine.
What are the official names of this protein?
Probable glycine betaine transporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1226_METJA
Sequence: MWGVVMNVEEIEEEYKTSIKTGLSTEEAKKRLKIYGYNEIPEKKVHPIIKFLSYFWNPIAWMIEIAAILSAIIKHWVDFVIILILLLVNGVVGFWEEYKAENVIEFLKQKMALNARVLRDGKWQIIPAKELVPGDVVRIRIGDIVPADIILVDGDYLVVDESALTGESLPVEKKIGDIAYSGSIVKKGEMTGIVKATGLNTYFGKTVKLVEKAEKVSSYQKMIIKIGDYLIVLAVILIAIMVAVELFRGKSLIETAQFALVLAVSAIPAAMPAVLSITMAIGALNLAKKDAIVKKLVAIEELAGVDILCSDKTGTLTKNQLVCGEIIALNGFSKEDVVLFAALASREEDADAIDMAILNEAKKLGLMEKIKNYKIKKFIPFDPVIKRTEAEVTNDEEFKVSKGAPQVILDLCNADEELRRKVEEIVDKLAENGYRALGVAVYKNGRWHFAGIIPLYDPPREDAPLAVKKIKELGVIIKMVTGDHVAIAKNIARMLGIGDKIISISELLKKLKRGEIKEEKFDEIVEEADGFAEVFPEHKYKIVDSLQKRGHLVAMTGDGVNDAPALKKADCGIAVSNATDAARAAADIVLLSPGISVIVDAIQEARRIFQRMESYVIYRITETIRILFFVELCILILGIYPITALMIVLLAILNDIPILAIAYDNVVEPKSPVRWRMREILMLSTALGLSGVVSSFLIFYISDVFLHLTIAELQSFVFLKLILAGHATIFVTRIRDRLWKKPYPSKLLFWGVMGTNIIGTIVAAEGIFMAPIGWDLALFMWLYAHVWMLINDEIKMILLKRLKID
What are the official names of this protein?
Putative cation-transporting ATPase MJ1226.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL3_ACTP7
Sequence: MIGLVGRKVGMTRVFTEDGVSIPVTVIEIEANRVTQVKTLENDGYSAIQVTTGSKKANRVTKPEAGHFVKAGVEAGRGLWEFRTEGEEFTLGQEINVDIFTDVKKVDVTGTSKGKGFQGGVKRWNFRTQDATHGNSLSHRVLGSIGQNQTPGRVFKGKKMAGHLGAERVTVQSLEVVRVDAERKLLLVKGAVPGATNSDVIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: SYDP_YERE8
Sequence: MDQNVSTALKSFTQRYIDLWQQQTGRPPASEELYGVPSPCNIETQDNQVFWLPQPFVGEANLANVERALEIQLHPDIHEFYTQQYAGDMKADLGDHRFTLLQVWSEDDFIRLQENLIGHLVTQKRLKLSPTLFLATTESEMTMASLCNVSGNMVLEEFGSGKRTLLASTLAHFLDALRPVFPE
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: F161_CAEEL
Sequence: MAPPKDPPVLRNLQATADLLDALQNDPSLLNDEEFIKRLSILRQKHEETTNFLAKKLGAPPLPTMMTSSEITQHRSSYKVTKSSSCHFQDEASPSDYQMPRHLDLKPRSSEVRVPVRAAPEPPREQSWSQTEYATLAHNQSHEALYEDPRHQVHATSSHQNPRHQSSRHHNIESTAPSQVSVTSSVQSVAALSGQNPRQQVHATPSHQIPRHQSSRTHQNSRQQVPSATSSTLQNPRHRTSSASRHHSTRNATSATVRQILANASTRHLSSAPHIATSVAMPSGLLLSSSNTKHVASSKSENPQFATSSHVVEESFLEDGMSTTREVPTIRDEVVAGDLKLSKNRSKSMHQLSKYTPQVTVPKPFQLSLRKSTGNTYAKKFMSGLITEKQKLEEDAKKALENTKFRAKPVPKSTYQPTNTFATEQKYVEAMRKKVAAKARRKFEVQNEMVRSKSEGNLASIKPLGYVPPSTYISPIPVKPNARSRSATMRATILIQEATTPKGIKSHRAQSNLTHHLRHGRCTMDASAVSLHRRTSPPDFEKIHAKITDNFRNTNSKPSTVPIPFKFASRSKSATSRHGNCQEQAPKPFKKSTENLPKTSKNRVPSTHATQLREELNRAKIELKKSEKSGKNGNFWAEDNKQRISSFLGARSKTEEDIAMRTKQKLQQQQETTQEYMRQLAEMKQRVLNGPLIMEKQTALAQEHRLKRKFEERMKSAKGRGIERVQSQEKQQSIGRRSSEVSGSGTFVVDKGYEESFESEDKSEKSGSSTPSESGSGSESENESRSSRSSKPKSSKSTSSKSSSSRSTSSSSEA
What are the official names of this protein?
Protein fam-161.
What is the protein family that this protein belongs to?
Belongs to the FAM161 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Note=Localizes to the base of the cilium and also to the proximal part of the ciliary axoneme, including the transition zone.