PharMolix/UniProtQA huggingface dataset:
Protein: VARB_VIOAR
Sequence: GLPVCGETCFGGTCNTPGCSCDPWPMCSRN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Varv peptide B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: PRMA_BACCZ
Sequence: MKWSEISIHTTEEAVEAVSHILHEAGASGVAIEDPAELTKEREQQYGEIYALNPDEYPAEGVLIKAYFPQTDSLHETIAGVKSSIDVLPSYDIEIGTGNITVNEVNEEDWATAWKKYYHPVQISDTFTIVPTWEEYTPSSPEEKIIELDPGMAFGTGTHPTTTMCIRALEKTVQPGDTIIDVGTGSGVLSIAAAKLGASSVQAYDLDPVAVESAEMNVRLNKTDDVVSVGQNSLLEGIEGPVDLIVANLLAEIILLFPEDAARVVKSGGLFITSGIIAAKEKVISEALEKAGFTIEEVLRMEDWVAIIARNA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBR1_YEAS7
Sequence: MRMEKTTDKSLSAGDMNDEYSRGPIDDIDCLNFFERAVQDPCCEACDTEDADEELRAKLSSFNFQPDSSPCNAKCQQTLNPLCKIDEALSAESELAPSRNGSVSEANSDTNSIASTVHDPVDSKYGGMPSLRKAKTTSYFASSSSNNTTMRNPLKKCNTNINGLLVNGRSSSSSRQSIPELFSGACTKKKNNVLLKSETPNSEFSSNSLQHCNSRSFSLPRSRSRSSAIAIPTHLYGLEKYVSPGLDTLTADPEESIERFSNNRPREISSCCPNDTGDTSSSLSHSNTSSSLNFPLGTNTNQFHQPRQPVQQQQSSKPNFGAGRKKSFIEMSLASSFAG
What is the function of this protein?
Participates in mitochondrial biogenesis and stress response.
What are the official names of this protein?
Mitochondrial biogenesis regulation protein 1.
What is the protein family that this protein belongs to?
Belongs to the ISF1/MBR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FMT_CAMJE
Sequence: MKKIIFMGTPSYATCILKALVENENFKLVALFTQPDKAVGRKQILTPSDTKAFLSQNYPSIPIFTPSSLKDKNIIREIKDLNPDFIVVAAYGKILPKAILDLAPCVNLHASLLPKYRGASPIQSAILNKDEKSGVCTMLMEEGLDTGAILESLECDIKDKNSSEVFELLANLAAKIILSTLLNFDKITPKKQEESLATLCRKIKKEDGLINLQNARELYQKYLAFTPWPGVFLENGLKFLELELVDELKQNAKMGEILELEKESFLLACKQGVLRIKKLQESGKKALDGRTYLNGKRLKSEDSLC
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: YODD_ECOLI
Sequence: MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHVSVDGREYHTWRELADAFELDIHDFSVSEVNR
What are the official names of this protein?
Uncharacterized protein YodD.
Protein: RECO_RHOOB
Sequence: MRLYRDNAVVLRQHKLGEADRIVTLLTRQHGLVRAVAKGVRRTKSKFGARLEPFAHIDVQLYPGRNLDIVTQVQTVDAFATDIVDDYTRYTTACAILETAERLAGEERAPALQLHRLTVGALRAVAEHHRPCELILDAFLLRAMGFAGWAPALDDCARCSAPGPHRAFHVAAGGAVCVQCRPPGAATPSPGVLDLMDALFRGDWASTEQVPEWLRGQASGLVAAHLQWHLERQLRTLPLIERARPHAAVGVEDSVRQDGDRDSTTRTPSSA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CYSG_PSEE4
Sequence: MDYLPLFHKLQGGRALVVGGGEIALRKARLLADAGAALRVVAPEVDGQLAALAREGGGEVLVRGYQSSDLDGCRLVIAATDDPGLNAQVSAHAQARSLPVNVVDAPALCTVIFPAIVDRSPLVVAVSSGGDAPVLARLIRAKLEAWIPSAYGELAGLAARFRDKVKALYPDVNQRRGFWENVFQGPIAERQLAGQGAEAERLLQAMVDGAPVQQGGEVYLVGAGPGDPDLLTFRALRLMQQADVVLYDRLVAPAIIEMCRRDAERIYVGKRRADHAVPQDQINRLLVDLARQGKRVLRLKGGDPFIFGRGGEEIEELADEGIPFQVVPGITAASGCSAYGGIPLTHRDYAQSVRFVTGHLKDGTSNLPWNDLVAPAQTLVFYMGLVGLPTICAELIRHGRAASTPAALVQQGTTRNQRVFTGTLADLPELVARHEVHAPTLVIVGEVVKLRDKLAWFEGAQNS
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: RS4_SYNPW
Sequence: MSRYRGPRLRITRRLGDLPGLTRKAAKRSYPPGQHGQARRKRSEYAIRLEEKQKLRFNYGVSERQLVRYVKKARAQEGSTGTNLLKLLENRLDNVCFRLGFGPTVPGARQLVNHGHVTVNGRVTDIASYQCKPGDVIAIRERKCSKQLAEGNLEFPGLANVPPHLELDKPKLNAKVVGRCEREWVALEINELLVVEYYSRKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: BIOB_SHEB9
Sequence: MSQLQVRHDWKREEIEALFALPMNDLLFKAHSIHREVYDPNEVQISRLLSIKTGACPEDCKYCPQSARYDTGLEKERLLAMETVLTEARSAKAAGASRFCMGAAWRNPKEKDMPYLKQMVQEVKALGMETCMTLGMLSEDQANDLASAGLDYYNHNLDTSPEYYGDVITTRTYQNRLDTLTNVRASGMKVCSGGIVGMGEKATDRAGLLQQLANLPQHPDSVPINMLVKVAGTPFEKLDDLDPLEFVRTIAVARILMPLSRVRLSAGRENMSDELQAMCFFAGANSIFYGCKLLTTPNPEESDDMGLFRRLGLRPEQGAAAKLEEESAVLAKAAAYQDKSSAQFYDAGAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ATPG_ECO5E
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUCS_STRAW
Sequence: MRLVIARCSVDYAGRLTAHLPSAPRLILVKADGSVSIHADDRAYKPLNWMSPPCTLKEGSGDEEGVWTVINKAGEKLIITMEEILHDSSHELGVDPGLIKDGVEAHLQELLADRIETLGDGYTLIRREYMTAIGPVDILCRDATGQTVAVEIKRRGEIDGVEQLTRYLELLNRDPHLAPVRGVFAAQEIKPQARVLATDRGIGCTVLDYNAMRGIEDDKLRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNS_TALSN
Sequence: MSHLNLATLDTSQHPYLPASSQTLFAAKAKRKFTFEDISKQIGRNEVATAAIFYGQAKASAEDIANLAKVLDIPLKLLEEQLSGFPDRGRSVEMPPKEPLIYRLYEIVQNYGYAYKAVLNEKFGDGIMSAISFSTKVEKETDADGNNWAVITLRGKWLPFSRF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: DNAG_METBF
Sequence: MQNTDTTKYIIHSKINADGVIERPDIVGAIFGQTEGLLGADLDLRDLQKTGRIGRIEVMVTAKGGKTKGNIFVPSSLDKVETSILAASLETIDRVGPCSAKIEVFQVEDVRAVKRKKIIERAKLIFTKMFDETVPESQELADEVRQSVRVDELTYYGKSRIPCGPNVLNSDAIIILEGRADILNLLRYGIKNTICVGGTNIPPEVAELTKKKTVTAFTDGDRGGELIIRELLQVADIDYVARAPDGKCVEDLVQKEVIRALRRKVPVEQIIEKYGIQEREGEESTRVERGSKRKIRAPEIAPRITEKKLHKRIKIHRVSSKPDLYEEELPEEETKGKASAKAFEKVSVKAAEKVSEMVPATAGKVKTRSIVAKPQISARKAPAAARVSREKPAEKVPSAVKVSRGEAVRVSPAPVKTVPVSPEATRFRPHVEALKGTLTARILDSQDKVIEEIAVRDLASRLKTYKENIQSVVFDGVITQRLVDIASSNAIKNLIGVKIGNIAKVPADMEVLTASML
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: MYL6B_HUMAN
Sequence: MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEEEVETVLAGHEDSNGCINYEAFLKHILSV
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light chain 6B, Myosin light chain 1 slow-twitch muscle A isoform, MLC1sa, Smooth muscle and nonmuscle myosin light chain alkali 6B.
Protein: RNC_CHLAA
Sequence: MSDRLAELERAIGITFRDRTLLQTAFMHRSLFNEQPHLLNHLTDNERLEFLGDSVLHFVTTTWLFETFPDQDEATLTNWRAALVSTKGLAECAAQFNLGQYAYLSRGEDNPGGRSRQKLLADLFEALVGAIYLDQGLETARAFIVPFWQARIEQIIHIDLDPTTRLQELMQARFKQLPDYSIEEERGPEHQREYVMAVTVAGRKFTGSGSSKKEAKRAAARKALAAWDKHGFTATAIDAQDERN
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GET3_ZYGRC
Sequence: MDLVVEPNLHSLINSSTHKWIFVGGKGGVGKTTSSCSIAIQMAQSQPHKQFLLISTDPAHNLSDAFGEKFGKDARRVTGMNNLSCMEIDPSAALKDMNDMAVSQANENGAQGDDGLGGLLQGGALAELTGSIPGIDEALSFMEVMKHIKNQEKGEGERYDTVIFDTAPTGHTLRFLQLPNTLSKLLEKFGEITGRLGPMLNSLAGAGNVDISTKLNQLKESVETIKDQFTNPDLTTFVCVCISEFLSLYETERLIQELISYDMDVNSIIVNQLLFADDDQEHNCKRCQARWKMQKKYLDQIDELYEDFHVVKMPLCAGEIRGLENLRKFSRFLNKEYNPAMDNKIIYELENKK
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting.  Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.  Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
What are the official names of this protein?
ATPase GET3, Arsenical pump-driving ATPase, Arsenite-stimulated ATPase, Golgi to ER traffic protein 3, Guided entry of tail-anchored proteins 3.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum. Golgi apparatus. Note=GET1 and GET2 are required for targeting GET3 to the endoplasmic reticulum.
Protein: RMR1_YEAST
Sequence: MSEEEAHKTVEVDDVGVQLDEGDEEDLLEYDDELVEEQPSDARIRNVAETLMKSELPKVTVEYKDTTFLLFTSDDKNESNNPIICENAALYQRPMGEFMESIRKFMGNRFGRLAFATKELVLQLKSLDLTLFEDNVYNNHISFSDVYTIFKILKERSESNFETDIPTHLAIELSTRPRFVSRYNALVELTESSATLKNIKPFSNDETHPLIVDDNDQYTHQNTSEVIVMDIDDDVGEDSED
What is the function of this protein?
Required for normal levels of gene conversion events during meiosis.
What are the official names of this protein?
Reduced meiotic recombination protein 1.
What is the protein family that this protein belongs to?
Belongs to the RMR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FGF1_XENLA
Sequence: MAEGDITTFNAITESFSLPIGNYKKPKLLYCNNGGYFLRILPEGVVDGTRDRNDLYITLKLSALSQGEVHIKTTETGCYLAMDSSGQLYGTLTPNEECLFLETLEENHYNTYKSKKYADMNWFVGIKKNGASKKGSRTHYGQKAILFLPLPASPD
What is the function of this protein?
Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration.  Functions as potent mitogen in vitro.  Acts as a ligand for FGFR1 and integrins.  Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades.  Binds to integrins.  Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
What are the official names of this protein?
Fibroblast growth factor 1, FGF-1, Acidic fibroblast growth factor, aFGF, Heparin-binding growth factor 1, HBGF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Note=Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery (By similarity).
Protein: COQ5_DANRE
Sequence: MAAPIRAFVLRVLSDSTRNIHHVLRCRSKYLCRRAAITARRGYSDSTEGRSTHFGFQTVPEEEKAEKVYKVFESVAKKYDVMNDAMSLGIHRLWKDTLLHIMNPQPGLRLLDTAGGTGDISFRFLEYTRSMYDRQQRLRAKSQQTPSWKDIAGHYVSDEEGPPQSRAVVCDINKEMLKVGKQRAEDAGITTGLSWVAGDAEELPFDDDQFDMYTIAFGIRNVTHIEQALQEAFRVLKPGGRFMCLEFSKVTNPLLARLYDAYSFQMIPVLGEVIAGDWKSYQYLVESIRKFPDQEIFKEMIEDAGFFRVQYFNLTGGIVAIHSGFKL
What is the function of this protein?
Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial, Ubiquinone biosynthesis methyltransferase COQ5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GATE_SULIN
Sequence: MSELNYEELGLKVGLEIHQQLNTSHKLFCNCSTNLKEDYKLTLERYLRPALSELGEVDVAALFEWKKGKKYVYRIPITTSCLVEADEEPPHAINEEALKIALAIAIALNSNIVDEIYVMRKIVIDGSNTTGFQRTAIVALGGMLKDEGVTIQTIAVEEDAARKIDERTDQVTYSLDRLGIPLIEISTGPDIRSPEQAERVALKIGQLLRMTGKVKRGIGTIRQDLNISIKGGTKIEIKGVQKLELIPDIVRYEAMRQFNLLKIKEELNKRGVSKNLILSNFVVKDLTELFKNTNSKIIKSGIEKGGLVYGIRAYKLKGILGWELIPKKRRFGTEIADYVRALAELGGLFHSDELPNYGITEEEINKVREALNATTEDGFILIVGERERLDKAVEVIRDRILLAFDGIPKETRGALDDGTTKFLRPQPSSARMYPETDIPPRRIDEKLLEDAKKFVPESPESKMKRYITLGLSEELAKEIIRDPRLDLFEELVNKYSPKVSPVVIASTITNTLKYVKSKGGDISKINEEDIEELIKSVYENKISKDSISEILLEYTTNKNVELKDVIRKYEALPTEELEKIIDDVISSNLDEIRKRKDKAVNLIMSKVMSKVKGRAEGKVILELIKSRLKNVME
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: RECU_STRPC
Sequence: MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDYYLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAKETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQIDNGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOD_PARP8
Sequence: MSPALSLFVTGTDTEIGKTLVSAALLRGFVRDGLRAAAMKPIAAGATLVNGVLHNEDADQLDAAANVLLPPDIRTPFMLKEPAAPHIAAAHESVTLDMARIVDAHEAALQMADVVVVEGVGGFRVPLTDSHDTADLAFALNLPVVLVVGMRLGCISHALLTAEAIAARGLRVVGWVANRVDPAMLFPDENIDTLRDRLARQYDAPLLGSVPHLSPASPDVAATHLDTTRLLHALRTAPR
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRA27_HUMAN
Sequence: MKMSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRCCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVCPRRWKLQVLDLQDVCENFWMVWSEAMARGSFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEVNCKWVLPILTQFTPYLGHMRNLQKLVLSHMDVSRYVSPEQKKEIVTQFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNAFSFCGNPISMATLENLLSHTIILKNLCVEVYPAPRESYGADGTLCWNRFAQIRAELMNRVRDLRHPKRIFFCIDNCPDCGNRSFYDLEADQYCC
What are the official names of this protein?
PRAME family member 27.
What is the protein family that this protein belongs to?
Belongs to the PRAME family.
Protein: MERA_ACICA
Sequence: MTTLKITGMTCDSCAAHVKEALEKVPGVQSALVSYPKGTAQLAIEAGTSSDALTTAVAGLGYEATLADAPPTDNRAGLLDKMRGWIGAADKPSGNERPLQVVVIGSGGAAMAAALKAVEQGAHVSLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDGGIAATVPAIDRSKLLAQQQARVEELRHAKYEGILDGNPAITVVHGEARFKDEQSLVVRLNDGGERVVAFDRCLVATGASPAVPPIPGLKESPYWTSTEALVSDTLPERLAVIGSSVVALELAQAFARLGSQVTILARNTLFFRDDPAIGEAVTAAFRAEGIKVLEHTQASQVAHVDGEFVLTTGYGEIRADQLLVATGRAPNTRSLALEAAGVAANAQGAIVIDKGMRTSTPHIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRTLTLDNVPRALANFDTRGFIKLVIEEGSGRLIGVQAVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG
What is the function of this protein?
Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase.  MerA protein is responsible for volatilizing mercury as Hg(0).
What are the official names of this protein?
Mercuric reductase, Hg(II) reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: PXYP1_XENTR
Sequence: MLLRNRFLLLLALAGLLAFLSLSLQFFSRWLPVSLQLKTEMQVFPEFPVRLIQVGQGREEGLGAKNRKRIMPEPLTEPPALNPLYEANLYCNTPGAKERSMEGHAPPNLKLLSVQVIIRHGDRYPLYTIPKTKRPDIDCVLEPGRKPSHPHLTDFISHMSKGVDTQMDGTLGSLPRLPNHILCEMGELTQTGVVQHLRNGQLLKEIYLKKHRLLTSAWTAKHLYFESTGKSRTLQSGLALLYSLLPNFDWKKINVKHQWSTIFCSNHCDCPMRNHYLEEEQRRQYNFRVKNSLLEKTYINMAKIVGIPTRQLRASNPIDSLLCNFCHNATFPCTKNGCIDLEHFKVIKTHQLEDEKERYEKQLYFKYALMATHPLLNQTANRMLRIAEGKKDELFALYSAHDVTLSPILSALGLREARFPRFAARLVFELWHDPEKANNHYVRVLYNGEDVTFQTSFCRDQLRSSKRPLCPLKKFSTFVQKDMFSSLNSTSYYDACHQRLF
What is the function of this protein?
Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains.  Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases.  Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
What are the official names of this protein?
2-phosphoxylose phosphatase 1, Acid phosphatase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: RTPR_LACDA
Sequence: MSEGISLSAEFIDRVKASVKPHWGKLGWVTYKRTYARWLPEKGRSENWDETVKRVVEGNINLDPRLQDSPSLELKQSLTEEAERLYKLIYGLGATPSGRNLWISGTDYQRRTGDSLNNCWFVAIRPQKYGDSKIVPSYLGKQEKAVSMPFSFLFDELMKGGGVGFSVARSNISQIPRVDFAIDLQVVVDESSESYDASVKVGAVGKNELVQDADSIYYRLPDTREGWVLANALLIDLHFAQTNPDRKQKLILDLSDIRPYGAEIHGFGGTASGPMPLISMLLDINEVLNNKAGGRLTSVDAADICNLIGKAVVAGNVRRSAELALGSNDDQDFISMKQDQEKLMHHRWASNNSVAVDSAFSGYQPIAAGIRENGEPGIVNLDLSKNYGRIVDGYQAGIDGDVEGTNPCGEISLANGEPCNLFEVFPLIAEEQGWDLQEVFALAARYAKRVTFSPYDWEISREIIQKNRRIGISMSGIQDWLLTRLGNRVVTGFKDDFDPETHEAIKVPVYDKRAIKMVDQLYKAVVKADQDYSKTLGCNESIKHTTVKPSGTVAKLAGASEGMHFHYGAYLIQRIRFQNSDPLLPALKACGYRTEADIYTENTTCVEFPVKAVGADNPNFASAGTVSIAEQFATQAFLQTYWSDNAVSCTITFQDSEGDQVESLLRQYRFIIKSTSLLPYFGGSLQQAPKEPIDKETYEKRSQEITGNVEEVFSQLNSDVKDLELVDQTDCEGGACPIK
What are the official names of this protein?
Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, RTPR.
What is the protein family that this protein belongs to?
Belongs to the class II ribonucleoside-triphosphate reductase family.
Protein: RS14_PASMU
Sequence: MAKQSMKARDVKRVKLAEKFYAKRAELKQIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGVLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: FXI1E_XENTR
Sequence: MSAFDPQAHSPPRCGPQFPSIGQEPPEMNIYCDSIFHPQTMPSPQRPSNFETADYSTTANPYLWLNGPSITPPPYLPGSNTSHFMPQSYGMQRQLLPNMHGLGGSDLGWLPIPSQEELMKLVRPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSPNGQISSDKPEGSPLNESPKNGEHHDMLGNSSPGTDDSSEKRSPPPSITPCLNNFLSSMTAYVNSANPVSRSVPLGLTNEPSDRMGQNMVGLNSYTPLSNMPSHGGSDWSSTISSSPFGYSSSVFNQFTPHFYNTINANNTLYNREGTEV
What is the function of this protein?
Transcriptional activator.  Activates ectoderm, in addition to inhibiting mesoderm and endoderm formation; required at the blastula stage for normal formation of both the central nervous system and epidermis, the two early derivatives of the ectoderm.  In addition, also required to maintain the regional identity of the animal cells of the blastula, the cells that are precursors of ectodermal structures.  Also plays a role in differential adhesion, which limits cell mixing as primary germ layers become specified (By similarity).
What are the official names of this protein?
Forkhead box protein I1-ema, FoxI1-ema, Ectodermally-expressed mesendoderm antagonist, FoxI3.
What are the subcellular locations of this protein?
Nucleus.