PharMolix/UniProtQA huggingface dataset:
Protein: CETN3_MOUSE
Sequence: MSLALRGELVVDKTKRKKRRELSEEQKQEIKDAFELFDTDKDQAIDYHELKVAMRALGFDVKKADVLKILKDYDREATGKITFEDFNEVVTDWILERDPHEEILKAFKLFDDDDSGKISLRNLRRVARELGENMSDEELRAMIEEFDKDGDGEINQEEFIAIMTGDI
What is the function of this protein?
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.
What are the official names of this protein?
Centrin-3.
What is the protein family that this protein belongs to?
Belongs to the centrin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus, nucleolus. Nucleus envelope. Nucleus, nuclear pore complex. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centrosome of interphase and mitotic cells. Localizes to centriole distal lumen (By similarity). Localization at the nuclear pore complex requires NUP153 and TPR (By similarity).
Protein: RL24_COXBN
Sequence: MAIKKIKKDDTVIVITGRDKGRQGKVLKVLPNSRLLVEGINLVKKHVKPNPNKNEQGGILERELSIHVSNVAIYNPAAKKADRVGIKTLEDGSKVRIFKSNGEVIDV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RRAB_SHEAM
Sequence: MSIERLLKAQQEETRDIVQSLLDDGSDPDAEYMIEHHFSSTNFDRLEKAAVDAFKLGFEVTDAEELELDDGSVILCFDAIANHALDVDLIDKACEQLINLAAKQKVDYDGWGTYFMGDDEDFDDEDDDEDYDKDGFPIERH
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity B.
What is the protein family that this protein belongs to?
Belongs to the RraB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZHP4_CAEEL
Sequence: MEAVHCFRCYKFPSKQIEFYLTNCMHMFCIECERLCHPPEEEPLKCIQCSKTPIRIVKMGPELPMTIKSMFTPISEEINQYTRDLTRVLTFQHRQRASLSTFLERKVAAFDRLRDAYSEEKTKKEHYKKQLEEAYHLLKSKEHEISKLKKQLAEQAPPPQTPPRSNSLKVASSRSLETPSMMRVFSDSMYETPVQIQRRFTKAQAKAEAEAEAPAKSPGSKAQTTKCTSNYQSHPPASFETPIHHPPKTSMGFTTPANPPHMFPYLKKHEAQREKHKEHRNSQ
What is the function of this protein?
Recruited co-dependently with zhp-3 to the synaptonemal complex between homologous chromosome pairs to regulate the formation and number of crossover events between homologs during meiotic recombination (PubMed:29521627, PubMed:30379819).  In the early stages of pachytene, in complex with zhp-4, recruited by the zhp-1-zhp-2 heterodimer to designated crossover sites along the recombination intermediate to stabilize other pro-crossover factors such as rmh-1, msh-5 and cosa-1 (PubMed:29521627, PubMed:30379819).  This in turn facilitates crossover and promotes the formation of chiasma in each meiotic nucleus at the late pachytene stage of meiosis (PubMed:29521627, PubMed:30379819).  Negatively regulates double strand break formation to promote formation of the crossover intermediate (PubMed:30379819).
What are the official names of this protein?
Zip homologous protein 4.
What are the subcellular locations of this protein?
Chromosome. Note=Co-localizes with zhp-3 to chromosomes from mitosis to early diakinesis in the germline (PubMed:29521627, PubMed:30379819). Co-localizes with syp-1, a component of the synaptonemal complex from early prophase to mid- pachytene (PubMed:29521627, PubMed:30379819). At late pachytene, localization at chromosomes is not dependent on syp-1 (PubMed:29521627). From mid-pachytene, co-localizes with cosa-1 at crossover sites of recombination intermediates, and gradually disassociates from syp-1 along both chromosome arms (PubMed:29521627, PubMed:30379819).
Protein: RNT_XANCP
Sequence: MPMNEPVDLQPSPSLLPMSRRFRGYLPVVVDVETGGFDWNKHALLEIACVPIEMDAQGHFFPGETASAHLVPAPGLEIDPKSLEITGIVLDHPFRFAKQEKDALDHVFAPVRAAVKKYGCQRAILVGHNAHFDLNFLNAAVARVGHKRNPFHPFSVFDTVTLAGVAYGQTVLARAAQAAGLDWNSADAHSAVYDTEQTARLFCKIANAWPGPASAG
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: LGUL_ARATH
Sequence: MASEARESPANNPGLSTNRDEATKGYIMQQTMFRIKDPKASLDFYSRVLGMSLLKRLDFSEMKFSLYFLGYEDTTTAPTDPTERTVWTFGQPATIELTHNWGTESDPEFKGYHNGNSEPRGFGHIGVTVDDVHKACERFEELGVEFAKKPNDGKMKNIAFIKDPDGYWIEIFDLKTIGTTTVNAA
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: KUP_STRS7
Sequence: MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQGGLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWLIIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLFGLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENHRGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKDSGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKITYPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYLIKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTVIVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKRPKRAQVYWFVNVRVTDEPYTATYKVDMLGTDYIVCVELYLGFRMPQTVPRYLRTIVQDLMESGRLPKQVQDYTITPGREVGDFRFVIIEERVSYARQLSTLERFVMQTKASIKHVTASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DIAA_ENT38
Sequence: MLERIKVCFTESIQTQIAAAEALPEAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEIYAKQVRALGHAGDILLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
What is the function of this protein?
Required for the timely initiation of chromosomal replication via direct interactions with the DnaA initiator protein.
What are the official names of this protein?
DnaA initiator-associating protein DiaA.
What is the protein family that this protein belongs to?
Belongs to the SIS family. DiaA subfamily.
Protein: PCDGG_PANTR
Sequence: MGSGAGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTARDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNGQVSYCIIASDLEQRELSSYVSISAESGVVFAQRAFDHEQLRAFELTLQARDQGSPALSANVSLRVLVDDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPDPSDLEAELQFYLVVALALISVLFLVAMILAIALRLRRSSSPASWSCFQPGLCVKSESVVPPNYSEGTLPYSYNLCVAHTGKTEFNFLKCNEQLSSGQDILCGDSSGALFPLCNSSELTSHQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-B4, PCDH-gamma-B4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ATPF_HETA4
Sequence: MENLTNIFLFLSNENEGIQLNTDIFEANIINLALLIVLVINVAKDVLGSILSARKASILDKIEEADKKLNEADKRFTEARLQWSQANIFGEDLEKKTYQRINAFHESQNLKNKDALLREYFSTLVVLDLKNEQVQKQVRNYVMELALIEVYGVFTKLVANKKFQENYSNYSVLLLEKLIGEK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RASF2_RAT
Sequence: MDYTHQTALIPCGQDKYMPKSELLLHLKTYNLYYEGQNLQLRHREEEDEFIVEGLLNISWGLRRPIRLQMQDDHERIRPPPSSSSWHSGCNLGAQGTTLKPLTVPTVQISEVDMPVENMEMHSPTDSRGLKPVQEDTPQLMRTRSDVGVRRRGNVRTSSDQRRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSAEEFALYVVHTSGEKQKLKNSDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYIKFEMPVLKSFIQKLQEEEDREVEKLMQKYTVLRLMIRQRLEEIAETPETI
What is the function of this protein?
Potential tumor suppressor.  Acts as a KRAS-specific effector protein.  May promote apoptosis and cell cycle arrest.  Stabilizes STK3/MST2 by protecting it from proteasomal degradation (By similarity).
What are the official names of this protein?
Ras association domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1.
Protein: UVRC_ECOSM
Sequence: MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGIRPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTC_SALPK
Sequence: MSLSVTRENFDEWMVPVYVPAPLIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGKLYAYMHYGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNTLNVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGASCG
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: AROC_SYNWW
Sequence: MVLRFITSGESHGKGLIGIVEQMPAGVEIGEEDINRELQRRQKGYGRGGRMKIESDRVEIFSGIRNGYSLGTPISYLIRNQDFENWQEIMATGECKRHEEKIVNRPRPGHADLAGAMKYNQSDMRNILERASARETAARVAAGAMFKKLLESFNIRVYSQVKSIGPVQVKTWQVNEQNWQDLREKVDESPLHSVDTEKEPLMREAIDQARSKGESLGGSFEVGVIGVPPGLGSYISWESRLDSQICALLMSIPAIKAAEIGEGIANSAEPGSRVHDEIFYSEEGGLHRKSNRAGGIEGGISNGETVWARAYMKPIPTLYKPLTSVNTKLWQEEKADIERSDICAVPAAAIVGESMLAFAIARAFLEKFSGDSLDEIRKSYTTYQAYLKRVWKWEKI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: DAPF_BAUCH
Sequence: MQFSKMHGLGNDFMVVDVVTQNVYLSPTKIRFLANRHSGVGFDQLLFVEPPYDPEIDFHYRIFNADGSEVTQCGNGARCLAHFVRMKKLTNKREIYISTQTSRMVLTIIENNMVRVNMGVPKFELPQIPFDMHQIEKKEILYLAKNYIFGGIVSIGNPHCIMIVNNVDSAQVSIIGPILEIHKYFSERTNVGFMQVINREQVLLRVYERGVGETQACGSGACAAVAIGIRLGLLAEQVQVALPGGKLVIYWRGPGQSLYMTGPAVHIYDGFIND
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_ACOGR
Sequence: MPRDGNEGMFTIPGFSQIQFEGFCRFVDQGLMEEFHKFPKIEDTDQEIEFQLFVERYQLVEPLIKERDAVYESLTYSSELYVPAGLIWKTGRDMQEQTIFIGNIPLMNSLGTFIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTSTIISDWGGRSELEIDRKSRIWARVSRKQKISILVLSSAMGSNLREILDNVCYPEIFLSFLNDREKKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQSNTFLLPRDVLAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQFGLALVRLENAVRGTICGAIRHKLILTPQNLVSSTSLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGHWGSIESPFYEVYQRSKETKMVFLSPSRDEYYTVATGNSLALNRGGIQEEQIVPARYRQEFLTIAWEQIHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSXXXXXXXXXXXXAALDSGVSAIAECEGKIIYTDTHKIVLSGHGDTISIPLVMYQRSNKNTCMHQNPQVRRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPERITHEIPHLEAHLLRNLDRNGIVALGSWVETGDILVGKLTPQTANESSYAPEDRLLRAILGIQVSTAKETCLKLPIGGRGRVIDVRWIQKKGGSSYNPETIRVYISQKREIKVGDKVAGRHGNKGIISKILSRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFECSLGLAGDLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVLIGKSYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPTPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MRAZ_PSEPF
Sequence: MFRGANAISLDAKGRLAMPSRYRDELDSRSSGQLIVTIDAVDPCLCVYPLDEWEIIETKLRALPSLREENRRLQRLLIGNAVDLELDGSGRFLVPPRLREYAKLDKRAMLVGQLNKFQLWDEDAWNAVSAADLAAIQQPGAMPDELRDLIL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NA227_NEMVE
Sequence: MASFKIVIVCLALLVAVASARRRDMMSDDELDYHFSKRGIPCACDSDGPDIRSASLSGIVWMGSCPSGWKKCKSYYSIVADCCNQ
What is the function of this protein?
Binds to site 3 of voltage-gated sodium channels and inhibits the inactivation process (PubMed:18538344).  Is highly active on DmNav1/TipE (drosophila) and is only extremely weakly active on rat Nav1. 4-beta-1/SCN4A-SCN1B, and on human Nav1. 5-beta-1/SCN5A-beta-1 (PubMed:18538344).  This reveals high specificity for arthropod over mammalian channels (PubMed:18538344).  In vivo, when released into the medium, this recombinant toxin induces impaired swimming, paralysis and death of the crustacean A. nauplii within several hours (PubMed:22048953).  Also causes paralysis of cherry shrimps immediately after injection at very low doses (PubMed:29424690).  Its effect on zebrafish (D. rerio) larvae is also rapid, since it induces tail twitching accompanied by impaired swimming after 20 minutes and complete paralysis within 45 minutes (PubMed:22048953).  It has also been observed to cause death of zebrafish larvae within 1 hour (PubMed:31134275).
What are the official names of this protein?
N.vectensis toxin 1 2, Nv1, Neurotoxin Nv1-116.27.1, Neurotoxin Nv1-12, Neurotoxin Nv1-7.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDK_METB6
Sequence: MDRTFVMIKPDGVQRGQVGGIVSRFEAKGLKLVAARFEVLPESRVIEQYQEHLSKPFFPSLKSYIRGGPCFLMVWEGRNVVAIVRKMIGATNPQEAAPGTIRGDFGIDIGRNVIHASDSPESAAREIGIHFKPAELFAYTRVDESVVYEY
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDA3_PANTR
Sequence: MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNAPVFPMSVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEEIKSLGLVLKKYLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIHSLSLPVLEDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLXYELQPGTGGARIPFRVGLYTGEISTTRALDEVDVPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPTEGACGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin alpha-3, PCDH-alpha-3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Q2OG_COMTE
Sequence: MIQAEKNPXL
What is the function of this protein?
Converts (3-methyl-)-quinoline to (3-methyl-)2-oxo-1,2-dihydroquinoline.
What are the official names of this protein?
Quinoline 2-oxidoreductase gamma chain.
Protein: ENDA_HYPBU
Sequence: MIRAVLLGLRAVVFDREAARRLYASGYYGKPLGIPKPRGSNFDAPLELGLLETLHLLERGMLEVYDEEGHRVSVEEVRRRAERFIPKFELLYKVYRDLRDRGYVVRSGLKYGSDFAVYERGPGLEHAPYLVHVMRVDEEIDPLEIVRAGRLSHSVRKAFILALTGPRDTPIRYLLLKWSKP
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: PCM1_CHICK
Sequence: MATGGGPFEEGMNDQDLPSWSNESLDDRLNNTDWGCQQKKANRSSEKNKKKLGGEAETRLTNDISPESSPGMGRRKTRTPHSFPHARYMTQMSVPEQAELERLKQRINFSDLDQINTNKSKDPVSGSQKKESGEPLQCKELFGAALNKDFLQNGQLSIQEDGRGEPTMDSSQARDPQQEAKEELENLKKQHDLLKRMLQQQEQLKALQGRQAALLALQHKAEQAVAVVDDSVVTETTGSVSGVSLTSELNEELIDLIQRFHNQLHDSQTQSVPDNRRQAESLSLTREISQSRNSSVSEHQSDEKAQLFNKMRMLQGKKQKMDKLLGELHTLRDQHLNNSSFFPASSSPQRSIDQRSTTSAASAPVGVVTVINGESNSLASAPYPPDSLASQNESEEDDNLNPTEKLQKLNEVRKRLNELRELVHYYEQTSDMMTDAVNENTKEEEETEDSGSDSEHGDPQPVTNIRNPQGISSWSEINSNSNVQCGTNNRDGRHLNTDCEINNRSAANIRTLKMSSTLDCHNREDDKHADLPHGEDDEVEEDRASEDSMSSHRSSLGDVAGDAEFEQKINRLMAAKQKLRQLQNLAAMVQDDDPEPQVLTANASNMGDFLGEMEETKQQPNNVRVSTNKLQKDAGLNEKAREKFYEAKLQQQQRELKQLQEERRKLMEIQEKIEVLQKACPDLQSAGLGNSPANRQTSPATSTPAMNECNTAGKPLLEFGESVPVGNELWSEMRRHEILREELRRRRKQLEALMAEHQRRRELAETISTVAASVKSEGSEAQRTPQQSRTENRTMATWGGSTQCALDEEDGDEDGYLSDGLDQAEEEEDAPSMNDSFSAYPNNQIPESVYYLKGNKDRWKNCRPLSADGNYRPMSKTRQQQNISMRRQENFRWISELSYVEEKEQWQEQINQLKKQLEFSVSICQTLMQDQQTLSCFLQTLLAGPYNVVPNNVASSQVHLIMHQLNQCYTQLSWQQNNVQRLKQMLNDLMHQQEQQCQEKPSRKERGSSAPPPPSPVFCPFSFPPQPVNLFNIPGFTNISSFAPGINYNPVFPCGFGDFAHSGFPQSSEQQQHPLDHNASGKTEYMAFPKPFESSSSTGAENQRSHRQPEDEVEKRSTWLNDSQEVKKDDQSQQKAGFPVSVQSIASGHKNQSDTSRRRNFDEESLESFSSMPDPVDPTTVTKTFKSRKASAQASLASKDKTPKSKNKRKNSSQLKGRIKNTGYDSASASSVCEPCKSTKSKHSEEVVHAKVFSKKNREQLEKIIKYSRSTEMSSETGSDLSMFEALRDTIYSEVATLISQNESRPHFLIELFHELQLLNTDYLRQRALYALQDIVTRHLSENNEKGRCIKSLNTATWIASNSELTPSESLASTDDETFDKNFPTEACQDCEQNDADNGSTMSTSSHFEPFATDDLGNTVIHLDQALARMREYERMKIEAESTLDSEGCSSNLQGATAAKLEGPSTSECLSVPQSSEVSAVPCPRIDTQQLDRQIKAIMKEVIPFLKEHMDEVCSSQLLTSVRRMVLTLTQQNDESKEFVKFFHKQLGSILQDSLAKFAGRKLKDCGEDLLVEISEVLFNELAFFKLMQDLDNNSISVKQRCKRKIETTEEIQSYAKEDKDETETVKPVQGLETYDGNEVPESIKSDASDQEEDEESESGPVAISLSKAETQALTNYGSGEDENEDEEIEFEEGPVDVQTSLQASSETATENEQISSQELSKTKGSDILSSEQQSVNVKGEQDAATILPHYLNVVENTPPLPVNTPESFIAASMKTEESSSSLPGNETQMLDTACVVNKSSAGSSESSMAGSPDTESPVLVNEYEAGSGNVSQKSDEDDFVKVEDLPLKLAVYSEADLLKKIASEAQTNSLSDELLGGGGEQDRELVGDAQTLKEPETFGAQSA
What is the function of this protein?
Required for centrosome assembly and function (PubMed:12403812).  Essential for the correct localization of several centrosomal proteins including CETN3 and PCNT (By similarity).  Required to anchor microtubules to the centrosome (PubMed:12403812).  Probably involved in the biogenesis of cilia (By similarity).
What are the official names of this protein?
Pericentriolar material 1 protein, PCM-1.
What is the protein family that this protein belongs to?
Belongs to the PCM1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasmic granule. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton, cilium basal body. Note=The majority of the protein dissociates from the centrosome during metaphase and subsequently localizes to the cleavage site in telophase.
Protein: FRUF_BIFLO
Sequence: MAEKAKAEGNNFVKKLLSSNLTWSIVAFILLVIICTIFQHDFLALSWNSNTGGLAGPLITMLQESARYLMIATGMTLVISTAGIDLSVGSVMAVAGAAAMQTLSNGMNVWLSILIALAVGLAIGCVNGALVSFLGLQPFITTLIMMLAGRGMAKVITSGENTDASAVAGNEPLKWFANGFILGIPANFVIAVIIVILVGLLCRKTAMGMMIEAVGINQEASRMTGIKPKKILFLVYAISGFLAAIAGLFATASVMRVDVVKTGQDLEMYAILAVVIGGTSLLGGKFSLAGSAVGAVIIAMIRKTIITLGVNAEATPAFFAVVVIVICVMQAPKIHNLSANMKRKRALKAQAKAVAA
What is the function of this protein?
Part of the high-affinity ABC transporter complex FruEKFG involved in fructose uptake.  Can also transport ribose and xylose, with lower affinity.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Fructose import permease protein FruF.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.