PharMolix/UniProtQA huggingface dataset:
Protein: CNBL3_ARATH
Sequence: MSQCIDGFKHVCSSFFRCFDIDIYKQSGGLGDPELLARETVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTNKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIEDKIDFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLSDEIIESIIDKTFEEADTKHDGRIDKEEWRTLVLRHPSLLKNMTLQYLKDITTTFPSFVFHSQVEDT
What is the function of this protein?
Acts as a calcium sensor.  CBL proteins interact with CIPK serine-threonine protein kinases.  Binds calcium ions.  Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner.  Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement.  Negatively regulates the enzyme activity of MTN1 in the presence of calcium.
What are the official names of this protein?
Calcineurin B-like protein 3, SOS3-like calcium-binding protein 6.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Lipid-anchor. Note=Tonoplast localization abolished by 2-bromopalmitate (2-BP) treatment.
Protein: ARMD1_HUMAN
Sequence: MTSIKEQAAISRLLSFLQEWDNAGKVARSHILDKFIETNQGKTAPELEQEFSQGASLFLVRLTTSLRITYMTDSCLEKLLRSIGIFLSAVSSNRYLIEFLEVGGVLTLLEILGLEKIKEEAKKESVKLLQVIANSGRTYKELICESYGVRSIAEFLAKSKSEETQEEVQVLLDSLVHGNPKYQNQVYKGLIALLPCESPKAQQLSLQTLRTAQPIIGTTHPSIVDCVLKVLGTMHLEVQYEAIELIKDLVGYDVRQALLKGLVALLIPSVKEISKLQAKILSDPSVLQLTPSLPMFLQQAAAAKAIGVLARNDMSIAEELLYLRVVRGLMAAMGNTDHSNSQRLASLTLECFVQMFPLVAEHVRKCMGEELYQLFLSNAEDLYMKIDSIQADILAANTVNVTKALCLHGSSYSMNTLYGSRDSAQMAYLTHFEEDVESKE
What are the official names of this protein?
Armadillo-like helical domain containing protein 1, p40.
Protein: RL17_DESVH
Sequence: MRHSNSGKKLGRTPSHRKALFRNLAKALLTHGKIRTTEIKAKELRRVVEPLITLALRNDLHARRQAYSVLGSHQLVKRLFDEIGPAFVGVPGGYTRVVKLGQPRRGDCAPLAIIEFTRTVAASEAAAAPAEAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL44E_METTH
Sequence: MKIPKERRTYCPNCRKHTVHEVLESKRRKASELKWGQRQFRRVTAGYRGYPRPLPSGNKPVKKLDLRLKCKECGKSHIKKKSFRAGRVEYVA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L44e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: NBPFC_HUMAN
Sequence: MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNLKERCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSTVVVDRKSSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSSPREMQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDKVNSSLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLLKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLAEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYRSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLSRELLAEKEPEVLQDSLDRWYSTPSVYLGLTDPCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYRSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHITFALDMDNSFFTLTVTSLHLVFQMGVIFPQ
What are the official names of this protein?
Neuroblastoma breakpoint family member 12, Chromosome 1 amplified sequence 1.
What is the protein family that this protein belongs to?
Belongs to the NBPF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_NEUCR
Sequence: MKDVEDIHRPMLNSLQSTSAKMKKIVLSVNAGSSSVKISAYSALFGQAPIQLAEAQISGLTAPPPTLRYTRHGEKVINDEEVKDQKVSTQADAFDILVKALIDDNGVPEISSKEDIAYICHRIVHGGDFVRPKLISDETYHNLEKLNDLAPLHNSTSLVIVHRCMSDMPKTTFNIACFDSQFHHTIPEHIRTYPINQDIARNNHLRKYGFHGISYAFITRATAEFLGKKVEDVNIIALHLGSGASACAIKGGKSLDNSMGLTPLAGLPGATRSGSVDPSLVFHYASDVGKLSPASTKDLHISRAEEILNKQSGWKALTGTTNFGTITAALDPSSSDTTSHLSPEEVAKMRLAFDIFVERICAYIGSYYVSLQGQVDALVFAGGIGEKSDRLRAAVIEQVSCLGFGPVDKEANETRVKEELDDSHDVIEIAPPNSKKGGKDGREHRVLVCKTDEQFEMARACAEDGEFWR
What are the official names of this protein?
Probable acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
Protein: TROPF_TALSN
Sequence: MLHGMSPECALSKLLSSLEFHTLYRYTMTQKHNFPSNNKDTLHLPRILCLHGGGTNARIFRAQCRALEKALRTSFRLCYAEALFPSQPGPDVTAVYRDFGPFRAWIDSPDANPVTMTEALQISICKAIMEDDQRGATGPVVGLLGFSQGAKVCASLILEQQLLGRTFGDHSHLPFRLPQWRFAVLLAGRGPLVTLSHLSVGADIMQKMAHLCENDDSSGLDSQENLGNVILTRELIQVPTIHVHGRKDPALDLHRKLYYDDFDPRYSKVMEWDGAHRVPLKSKDVATLVKEINVLWASVSHSNVQG
What is the function of this protein?
Esterase; part of the gene cluster that mediates the biosynthesis of the tropolone class of fungal maleic anhydrides (PubMed:22508998, PubMed:24863423).  The pathway begins with the synthesis of 3-methylorcinaldehyde by the non-reducing polyketide synthase (PKS) tropA (PubMed:22508998).  3-methylorcinaldehyde is the substrate for the FAD-dependent monooxygenase tropB to yield a dearomatized hydroxycyclohexadione (PubMed:22508998, PubMed:24863423).  The 2-oxoglutarate-dependent dioxygenase tropC then performs the oxidative ring expansion to provide the first tropolone metabolite stipitaldehyde (PubMed:22508998, PubMed:24863423).  Trop D converts stipitaldehyde into stipitacetal which is in turn converted to stipitalide by the short-chain dehydrogenase/reductase tropE (PubMed:24863423).  The next steps involve tropF, tropG, tropH, tropI and tropJ to form successive tropolone maleic anhydrides including stipitaldehydic, stipitatonic and stipitatic acids (PubMed:24863423).
What are the official names of this protein?
Esterase tropF, Tropolone synthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the LovG family.
Protein: BH092_ARATH
Sequence: MDNFFLGLSCQEENNFWDLIVADISGDRSVSVPIRSAFRSYMKDTELRMMSPKISSSKVNVKKRMVNLLRKNWEEKKNTVAPEKERSRRHMLKERTRREKQKQSYLALHSLLPFATKNDKNSIVEKAVDEIAKLQRLKKELVRRIKVIEEKSAKDGHDEMSETKVRVNLKEPLSGLDSMLEALHYLKSMGTKLKTVHANFSPQEFSATMTIETQIRGEEVEKRVERRLQETEWKLLFLPEASFYKDY
What are the official names of this protein?
Transcription factor bHLH92, Basic helix-loop-helix protein 92, AtbHLH92, bHLH 92, Transcription factor EN 22, bHLH transcription factor bHLH092.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPX_SALDC
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: DPO3_STRP6
Sequence: MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQFEAFGFGTLTIDMVSDQEMTEHLTKNFVSSRQALVEKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQVKEIVHHERKDLMPEGQKRVEFHAHTNMSTMDALPTVESLIDMAAKWGHKAVAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYDPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGIPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGIEQVIRDLIEVGKRANKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLGKDLAYQVVVENTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAEVERLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVEKMDEMSILGNMPEDNQLSLFDDFF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_STAA2
Sequence: MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: KGUA_LACDA
Sequence: MADKGLLLVLSGPSGVGKGTVKSAIVEHKVFPFEYSVSMTTRKPREGEVNGKDYYFVTREEFKQAIADNQLLEYNEYVGNLYGTPLGPVKEMLAAGKDVLLEIDVNGARTVRQQMPEGVFIFLTPPDLHTLRDRLEHRGTESEDVIRGRIAQARKEILVMQDYDYAVVNDTVANAVNHIKAIVDAEHVSVRRVIDDYRKMVKED
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_ECO45
Sequence: MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DGP11_ARATH
Sequence: MFFRPCVHTVGRYSRARVPGLLSSLFFYRSCNNVLTNSLPTVTTAGRVSRYGYICRRSSTSAAERGVFLPFALTCRRNIHSIHEDEKKLERWKKIEESHPLDELVLDSVVKVFSNSTEYSKSKPWKTLDQKSSRGTGFAIAGRKILTNAHVVMAMNDHTFVDVKRHGSQIKYKAKVQKISHECDLAILEIDSDEFWKGMNPLELGDIPPLQEVVSVVGGENICITKGLVLRVETRIYDYSDSDLLSIQIDATINDENSGGPVIMGNKVVGVVYEIGFVIPTPIIKHFITSVQESRQYSCFGSLDLSYQSLENVQIRNHFKMSHEMTGILINKINSSSGAYKILRKDDIILAIDGVPIGNDEKVPFQNKRRIDFSYLVSMKKPGEKALVKVLRNGKEYEYNISLKPVKPNFTVQQFYNVPSYYIFGGFVFVPLTKTYLDSEHHQVKISERLADDINEGYQSLYGAQVEKVNGVEVKNLKHLCELIEECSTEDLRLEFKNHKVLVLNYESAKKATLQILERHKIKSVISKDICLPMLLDDPFKDNKINLLPWSVLPLMFDFS
What is the function of this protein?
Putative serine protease.
What are the official names of this protein?
Putative protease Do-like 11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion membrane.
Protein: ENLYS_BPPH2
Sequence: MQISQAGINLIKSFEGLQLKAYKAVPTEKHYTIGYGHYGSDVSPRQVITAKQAEDMLRDDVQAFVDGVNKALKVSVTQNQFDALVSFAYNVGLGAFRSSSLLEYLNEGRTALAAAEFPKWNKSGGKVYQGLINRRAQEQALFNSGTPKNVSRGTSSTKTTPKYKVKSGDNLTKIAKKHNTTVATLLKLNPSIKDPNMIRVGQTINVTGSGGKTHKVKSGDTLSKIAVDNKTTVSRLMSLNPEITNPNHIKVGQTIRLS
What is the function of this protein?
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
What are the official names of this protein?
Endolysin, Lysis protein, Lysozyme, Muramidase, Protein p15.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.
Protein: VATC_HALS3
Sequence: MSASGPANYEYVVARIRHRRAGLFGDDEYRKLLRMGTGEIARFMEDSTYKDAVDSLASRHRGMDLVEYALNEGLAAEFDALLSWSEGRLYDQLAKYLRKFDAWNVKTVFRGLYSHADTDAIRADLVDAGEFDAAFLDELLSADSVETVVDALSGTIFDTYLEPAFADYEDEDSLVPLENAVDRAYYENLNPSQPATAAQDSPEALYAEFLTAEIDFRNARNALRLARSGVSVDPAAYFIEGGTLFEASEMTTLVERQSDLVSRIQDSTYGDELSTALTALEESDSLIGFEHALDRALLSYSDHLSYVYPTSVCPVLAYVLAKEREVDNIRAIARGREAGMSEDEIQAELVML
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: YFDS_ECOLI
Sequence: MRMNVFEMEGFLRGKCVPRDLKVNETNAEYLVRKFDALEAKCAALENKIIPVSAELPPANESVLLFDANGEGWLIGWRSLWYTWGQKETGEWQWTFQVGDLENVNITHWAVMPKAPEAGA
What are the official names of this protein?
Uncharacterized protein YfdS.
What is the protein family that this protein belongs to?
To the N-terminal region of phage HK97/HK620 Gp37/hpaH.
Protein: PNCB_SALHS
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLQEDEFQWLSGLPFFKPDYLNWLREFRYNPDQVCVTNDNGKLHIRLTGPWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALTADLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQISPDLATSQRAALAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLQKAVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: HIS9_PSEAE
Sequence: MRLALFDLDNTLLAGDSDHSWGEWLCQRGLVDAAEYQARNDAFYADYVAGKLDVLAYQAFTQAILGRTEMAQLETWHRQFMQEVIEPIVLAKGEALLAEHRAAGDRLVIITATNRFVTGPIAERLGVETLIATECEMRDGRYTGQTFDVPCFQGGKVVRLQRWLDENGLDLEGASFYSDSLNDLPLLEKVSRPVAVDPDPRLRAEAEKRGWPIISLR
What is the function of this protein?
Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine.
What are the official names of this protein?
Histidinol-phosphatase, Hol-Pase, Histidinol-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. SerB family.
Protein: PROA_RHIEC
Sequence: MLDTVAPSPDIDALMNDIGRKAKAAARPLGFASTEAKNKALNAMADAIMANKAHILAENAKDLKDIEGSETLASFVDRLTLNDKRIAEMAEGIRAIAALADPVGEVIAAWDRPNGLKIERVRTPLGVIGVIFESRPNVTADAGALCLKAGNAVILRCGSDSRRSSQAIHVCMVEGLKAAGLPEHAIQLVPVTDRAAVGAMLRGLEGAIDVIVPRGGKSLVARVQNEARVPVFAHLEGLCHIYVDASADLEMAKKIVVNAKMRRTGICGAAETLLVDGAAIDTHLTPLLEVLTDAGCEIRASAAVLKVAPGLKTATEEDWSTEYLDAIISVATVDGISGAIAHIQTYSSNHTEAVIAEDPAVVQRFFTEVDSAILLHNASTQFADGGEFGMGAEIGIATGKMHARGPVGVEQLTSFKYRVRGAGQTRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEF_SIVMK
Sequence: MGGAISMRRSKPAGDLRQKLLRARGETYGRLLGEVEDGSSQSLGGLGKDLSSRSCKGQKYNQGQYMNTPWRNPAEEKEKLAYRKQNMDDIDEEDDDLVGVSVRPKVPLRAMTYKLAIDMSHFIKEKGGLEGIYYSARRHRILDMYLEGIIPDWQDYTSGPGIRYPKTFGWLWKLVPVNVSDEAQEDERHYLMQPAQTSKWDDPWERF
What is the function of this protein?
Interferes with TCR signaling from the cell membrane.  Interacts with CD247/TCRZ (TCR zeta chain) and exert potent down-regulation of cell surface TCR/CD3 complexes (By similarity).
What are the official names of this protein?
Protein Nef, 3'ORF, Negative factor, F-protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus primate group Nef protein family.
What are the subcellular locations of this protein?
Host cell membrane; Lipid-anchor; Cytoplasmic side. Note=Associates with the inner plasma membrane through its N-terminal domain.
Protein: CH10_DESVV
Sequence: MNLKPLNDRVLVKRLESEEKTAGGLYIPDTAKEKPSRGEVVAAGPGKTADDGKLVAMTVKAGDMVLFNKYAGTEIKIDGVEHLVMREDDILAIIE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_POPAL
Sequence: MVREKVRISTRTLQWKCVESRADSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRAKSKKIPHEFSTITGIQESIHEILMNLKEIVLRSNLYGTHNASICVKGPGCVTAQDIILPPSVEIIDNTQHIASLREPIDLHIGLEIERNRGYCMKPPKNFQDGSYSIDAVFMPVRNANHSVHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLIDLFIPFLHAEEESFHLEKNQHKITLPLFAFHDRLAKLRKNQKEIALKSIFIDQLELAPKIYNCLKRSNIHTLWDLLKNSQEDLMKIEHFRIEDVKHIFGILKIEKHFTINLPKNKF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, PEP, Plastid-encoded RNA polymerase subunit alpha, RNA polymerase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ADEC_METKA
Sequence: MARSNRRGGRGDPEDDPAWAPPGHRCAGERAVGGPTVIPRAYLPAVPAGGNESRAFQGRFVDPWFSGIRTGYVIWDGGRLLGVTRNEPEHADVIDVDGIICPGFVDAHVHVESSGLRPARYAEIVVREGTTAVVWDPHEVVNVSGELGLEWAVKTAEEALPFKFYIALPSCVPALGPPYETVEGEITVDVARKFASHPMVVSVGELMDVAGVMEGEKDEFIELKSLYGLTVDGHAPGLTGFEAMRYFAAGPETDHECSTAEEFTSRRELGVWTFVRQGSSSKDMEVALETLEDLRGVCFVTDDLHVKDMDEISLRKIVGRAIEAGFDPLESLSAVTLNPSLCYGLQSGRLVPGFHADIVVVEDLDENMELTDVWIGGKRSERVRFRDAEAELPDVELSVDPREVSFQDGKYEVRCVGLVRGSIRTEEIVREITVKDGAVKDDDVAFLVVTDRYGQGSWSIGFVEGFEELDCAVVSTVAHDSHNVVVAGRRLDDVRRALQLVSEVGGCVGAVAGDRAEFVRLDVAGLMSSSDPEEVKKSYEDVLELIRSSSGVDWDPFQALSFVTLPVVPELRLTDRGLVKVEPDEIRFVDIITDGDPVE
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: DNAG_PYRNV
Sequence: MGALTIVAKYMIVAQIEVNGSVDKSDIIGALFSQTEGLLGKDMDLRELQMMGRIGRIEVDIFEKNSKTKAKIYIPSNLDRYETALVAALIESIERVGPYLANIKVLEIKDLREEKRRRIIEKAKELVKMIEEEILPDTKEIIEKLKEDVAKAEIVEYGPEKLPAGPDVEKSDSVIIVEGRADVVNLVKHGYRNVIAIEGISRGIPQTVIDLSKKKSVTVFIDGDKGGELVLRELLKVAHIDYIARAPPGKEVEQLTAKEIAKALRNKVTLEEWLAQQKAAGEKTEAPAQPTQQQPPPAEAPIQFPFDMSKKVEEMLGTLEAEIYDANWGLVKKLPVRELPDFLTGEGDSFYAIVMDGIVTQRIVDLAAKKGVKVIVTARVGPLTKVPEDMKIITFEKLTQKVA
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: Y312_JANMA
Sequence: MQIWVDADACPNVIKDVLFRVADRLQVQVTLVANKLLRTPPSRFIKAIQVPAGFDVADNEIVRLVQAGDLVITADIPLAADVLEKGGHPLNPRGEFYTKDNIQQHLTMRSFMDDLRSSGVDTGGPSAFSQGDIRAFANQLDRYLARQRSKG
What are the official names of this protein?
UPF0178 protein mma_0312.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: HSL21_DICDI
Sequence: MTILGSISSIGNVKLISKSNNLSSLSNSSSSLQSMNSIQCGGGCGNGGLLGGVGGLVGGVLVGTGVIVGSVLHGVGSILTGGSNNCGCN
What are the official names of this protein?
HssA/B-like protein 21.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: QUEA_ECOL5
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDQRSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YI71_SCHPO
Sequence: SFAYSGNSESVWTGENITSIWKTILINETGSYCVAARPMTMDGAEFNLDLMGYSVSEDQINNDEIGIWNYISVAEMGGVLLFLSYWIWTCLHFSKIIFPAQKVICLYIFLFALNQTLQECIEEYVFSSECIKYRQFYSVYEIIDFLRTNFYRLFVIYCALGFGITRTVPKYLMIKGISIVIALCSVYWISLYKDVYVVSEIFDMIQYEVSPAIWVYSICHLLKQCTSVTTYENASKARFFRRMLNAFIFIFCASPMLHYLSNIIFGNFDYRLSVIIGDLFTFMEKIAFPCYIMFPTHNEALAYNRNVAEEAQEKMI
What are the official names of this protein?
Uncharacterized membrane protein SPAC977.01.
What is the protein family that this protein belongs to?
Belongs to the UPF0742 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Membrane; Multi-pass membrane protein.
Protein: HOX8_ORYSI
Sequence: MRSYMDGGGAAAYEEEEEEVEDDDGGGGGGGGGGGGGLGEKKRRLAAEQVRALERSFEADNKLDPERKARIARDLRLHPRQVAVWFQNRRARWKTKQIERDFAALRSRHDALRLECDALRRDKDALAAEIADLRDRVDGQMSVKLEAVAADEHQPPPPPPPPPLAYNSKVVDGSTDSDSSAVFNEEASPYSGAAIDHHHHQTPASYDTAGFTSFFAPSTTLTSSLSFPSMFHASSHFDGHQELLVGGGGAGAVADADLGGAGFFAGDEHAGGLSWYGAEGW
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HOX8, HD-ZIP protein HOX8, Homeodomain transcription factor HOX8, OsHox8.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus.