PharMolix/UniProtQA huggingface dataset:
Protein: PUR7_CLOBB
Sequence: MEKLEMLYEGKAKQIYATDKADEVVIYYKDDATAFNGEKKGQITDKGVMNNKITSILFEQLEKQGIKTHFIKKLNDREQLCKKVSIVPLEVIVRNVAAGSMAKRLGLEEGTKLKTTVFEFSYKDDELGDPLINSYHAVAIGAATFEEIDTILEMTAKINNILKEAFAKENINLIDFKIEFGKCADGTIVLADEISPDTCRFWDATTGEKLDKDRFRRDLGNVEDAYIEILKRISK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: LIM4_CAEEL
Sequence: MDAHLVQAKKTSTASELSDSSLTFPFIGDYLSSPSLTTSDYVSDCSNLTVEGPVPANQEFSSSDESSVYISSALRLADYAFTPDDNIRIKPDAVIVICTQCQHQIQDKFFLSIDGRNYHENCLQCSTCENPLSNKCFYKDKTFYCKGCYFRTHVTSTASSCRELGPKCASCDRTIQATDWVRRARNYVYHLACFSCNQCKRQLSTGEEYALQEGNLLCKQHFLELVEGDSGVSSQKAKTKRVRTTFAEDQLSVLQTYFNRDSNPDGADLEKIASMTGLSKRVTQVWFQNSRARQKKWHQKSEGDNGDSQRSSVGPSSPSQKSDSSSEMMYPTSVTTSVEDAIPDSIVILGSLQFD
What is the function of this protein?
Transcription factor that binds to the promoter of target genes (PubMed:26305787, PubMed:16168406, PubMed:26341465).  Regulates genes involved in serotonin synthesis and release in serotonergic ADF neurons (PubMed:26305787, PubMed:16168406).  Involved in specification of neuron cell fate, olfactory receptor expression, locomotion, and foraging behavior (PubMed:10421632, PubMed:26305787).  Required in AWB olfactory neurons to repress AWC cell fate and promote the AWB cell fate during early development (PubMed:10421632).  Cooperates with additional factors to direct the differentiation of the olfactory neurons, functioning with the transcription factor sox-2 to suppress AWC terminal differentiation and promote AWB neuron differentiation (PubMed:26341465).  Involved in regulating terminal specification and maintenance of the SMB sensory/inter/motor neurons (PubMed:26305787).  Plays a role in regulation of RID motor neuron differentiation, but is dispensable for motor axon outgrowth in the dorsal nerve cord (PubMed:14568548).  May regulate its own expression (PubMed:10421632, PubMed:26305787).
What are the official names of this protein?
LIM/homeobox protein lim-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y092_METJA
Sequence: MIKITVKRFNGEKEYLESYEVPENITVLEALEYINKHYEANILFRASCRNAQCGSCAVTINGEPRLACETKVEDGMIIEPLRGFKVIRDLIVDREPYYKKLLGIKNYLIRKNYPEELEILIPKYVEENKELRGCIDCLSCLSVCPAREVSDYPGPTFMRQLARFAFDKRDEDGREITAYFENIYNCTTCAKCVEVCPKEIDIVHRAIEKLRALAFSKGYYIENHLKVRENVLKYNRSVVEEELPLLKQVADFYPAESEKLRVAFFTGCLVDFRLQNVGKDAIKVLNAHGVSVVIPKNQVCCGSPFFRTGQRDVAEMLKRKNLEIFNKLDVDCVVTICAGCGSTLKNDYKERKFEVKDITEVLTEVGLLKYKPLKMRITYHDPCHLRRGQKIYKQPREILKSIPELEFIDIEARCCGAGGGVRSGKPDIANLIGKSRARMIYDANVDAVITVCPFCEYHIRDSLKRFKEENKIDKEIDVMNIVSLLAKVI
What are the official names of this protein?
Uncharacterized iron-sulfur protein MJ0092.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
Protein: ATP6_HELHP
Sequence: MDERLFTFAGLINPNHDFIIGFHTLLVAVILLILARYATHKMQVVPSGIQNVFEFIISGIISFAKDIVGEQVARKYFPLAATIAFLVFFGNAIGIIPGFEAPTSSWSFTLVLALVVFFYYHFEGIRAQGVLKYFKHFMGPVWWLAPLMFPVEIISHFSRIISLSFRLFGNIKGDDMFLLVMLMLAPWIVPVAPFAILTFMALLQAFVFMILTYVYIHGAVVVDEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRF_FRATF
Sequence: MINDILKDAENRMKKSLEVLADDLAKIRTGRAHPDLLAHVTIDYYGVETPITQAANITVLDARTLGITPWEKGLSSKIEKAILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSETEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDIQKITDKMIAQADALAAKKEQDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SHIDS
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: FOSB_HALH5
Sequence: MRIQGINHLLFSVKCLERSIEFYKKALGAKLLVKGRTTAYFDLQGIWLALNEEPDIPRNEIHQSYTHIAFTVGEEEMEEAYERLAGLGVNILKGRPRDPRDRQSIYFTDPDGHKFEFHCGTLNDRLDYYREAKPHMTFFDD
What is the function of this protein?
Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin.  L-cysteine is probably the physiological thiol donor.
What are the official names of this protein?
Metallothiol transferase FosB, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family. FosB subfamily.
Protein: MTNA_NEOFI
Sequence: MASILQAIRYSRGKLAIIDQLQLPYVEKFITIQTPEDAWHAIKEMRVRGAPAIAIVAALALASELNTLIVHDKLSSGAEEVKLFIREKLDYLVSSRPTAVNLSDAARKLESTISDHADTPGATGRTVAEAFIRAAEDMMTKDLDDNMRIGKNGAEWIIKHALAARKSTATVLTHCNTGSLATSGYGTALGVIRALASKKALEHAYCTETRPYNQGSRLTAFELVHDRLPATLITDSMVAALLANTKAEVDAIVVGADRVAANGDTANKIGTYGLAVLAKYHGVKFLVAAPLTTIDLGTKSGEDIVIEERPAAEVTKIRGPVDGDHSADIVKLETVHIAAKGINVWNPAFDVTPSTLIDGIITEVGVIEKGTDGQFHLERLFIDNSAS
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CASP5_ARATH
Sequence: MKSGQAEIMETSKGIQKSGLMSRRIAILEFILRIVAFFNTIGSAILMGTTHETLPFFTQFIRFQAEYNDLPALTFFVVANAVVSGYLILSLTLAFVHIVKRKTQNTRILLIILDVAMLGLLTSGASSAAAIVYLAHNGNNKTNWFAICQQFNSFCERISGSLIGSFIAIVLLILLILLSAIALSRRH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion.
What are the official names of this protein?
Casparian strip membrane protein 5, AtCASP5.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain.
Protein: MOBA_STAAE
Sequence: MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAL_PHATC
Sequence: MANFIKPYNDDPFVGHLATPITSSAVTRAILQNLPAYRFGLTPLLRGLEIGLAHGYFLMGPFVKLGPLRDSEIGLLAGFLSTVGLIVILTLGLTIYGVAAFGQEKTQSSNENDLQTKKAWDQFKGGFFVGACGSAGFAFICLSSIPSFITN
What are the official names of this protein?
Photosystem I reaction center subunit XI, PSI subunit V, PSI-L.
What is the protein family that this protein belongs to?
Belongs to the PsaL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ISPD_BURTA
Sequence: MTSRLFALIPCAGTGSRSGSALPKQYRTLAGRALLHYTLAAFDACSEFAQTLVVISPDDAHFDARRFAGLRFAVRRCGGASRQASVMNGLIQLAEFGATDADWVLVHDAARPGITPALIRTLIGALKDDPVGGIVALPVADTLKRVPAGGDAIERTESRNGLWQAQTPQMFRIGMLRDAIQRAQLEGRDLTDEASAIEWAGHTPRVVQGSLRNFKVTYPEDFDLAEAILAHPARAS
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: GYRB_STAAN
Sequence: MVTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANKIEVVIEKDNWIKVTDNGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLNENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEEKDRLSGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKAREVTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRELDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANLDF
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8793_DICDI
Sequence: MYDVVDLTPTYSPTLKPMLSQQYQTVPPFIIPPNDPNSPSPLSSPSLLSLHQIQMHHQQQLQLLQQQQQQLQQQHQNQVVNQPIQPLQPQPSAFLLNHPNTITTPPLQPMMTPNTIISINSLPPTTTTTTTTTTTTTIPNNNNNITLSPQHHHGQQQHHQHPHLRVDISNNNNSVVDQLPQQQQTNVNNNNNNNNNNNNNNNSNNNNNNNNDFSTPNSFSVPTTPMVAPQMQFPQPPPPLSALNTPNNSTSNPTTPRNERDLLRRLAVANSNNNLNNNLNNLNNNNNNNNNNNNNNNNNNNNNSNNNNINNNNNINNNNNLNNNNLNNNNLPIIQPLNLNNNNNNNNNNNNNNNNNLINPFLNEAIDEQVVPKGSTSPLITSSKKRIKLNV
What are the official names of this protein?
Uncharacterized protein DDB_G0286175.
Protein: SCA4_RICSL
Sequence: DTSEFDPLANKEYTEEQKQTLEQEQKEFLSQTTTPALEADDGFIVTSASSAQSTPSMSALSGNISPDSQTSDPITKAVRETIIQPQKDNLIEQILKDLAALTDRDLAEQKRKEIEEEKEKDKTLSTFFGNPANREFIDKALENPELKKKLESIEIAGYKNVHNTFSAASGYPGGFKPVQWENHVSASDLRATVVKNDAGDELCTLNETTVKTKPFTLAKQDGTQVQISSYREIDFPIKLDKADGSMHLSMVALKADGTKPSKDKAVYFTAHYEEGPNGKPQLKEISSPKPLKFAGTGDDAIAYIEHGGEIYTLAVTRGKYKEMMKEVELNQGQSVDLSQAEDIIIGQGQSKEQPLITPQQTTSSSVEPPQYKQQVPPITPTNQPLQAETSQMPQSQQVNPNLLNTATALSGSMQDLLNYVNAGLTKEIDSNKQIDLIKEAAKAILNNEKSDIAEKQANIIALAENTVNNKNLKPDAKVAGVNAVLETIKNDQNTPDLEKSKMLEATVAIVLNSENLEPKQKQQMLEKAVDVGLSLKDDASRAAAIDGIKDVVIKSNLSPEDKGTMLIAVGDKVNVSELSNAEKQKLLGSVLKKKGVEAQVLSPAQQQLMQQHLYKITAEQTKKDTIKKVNDILFDPLSNTELKTTNIQAITSNVLDGPATAEVKGEIIQEITNTVAGSSLEAQDKAAIIKGVGETIATHSDTSLSLPNKALIMASAEKGIAESQTNLPDRELMTKGLVDGIYEGKGGPEITKAVSSGIDNSNINDSEKEALKKAKDAASEAALDRDTQNLTEGFKGQNIEEHKPHDDIYNKAREVINAVNPVIEALEKFKEPVVSAEERIVQETSSILNNISKLAVEKVNNFRAMLSPTGNLKTLEEKKEESIKKVDELVKAFGTKSSTEEQQSFIKTNLIDDKTLSKEVRLQTIDKLLQEQKRAEAIENPSVKTEDVRVVSGKSKLKPISKDNPDIEKAKMVVGRDRVNIKGNIKIMGALMNARDIIQSENLNKSTPIKRE
What are the official names of this protein?
Antigenic heat-stable 120 kDa protein, 120 kDa antigen, Protein PS 120, PS120.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_NEOYE
Sequence: MSITKNVKETKAVGKYIRLSPHKVRRVLDQIRGRKYQEALIILEFMPYRVCSHIKQILESAAANAEHNDGLNKNQLFVSKAFADKGPTLKRFQPRAQGRAFPIHKPTCHITLGVSEL
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRMD_CLOD6
Sequence: MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNNKHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQMSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGVLNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITKERRFDLYKKSNEK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_CHLPB
Sequence: MSTSPDNLFCPEQNFYGPDSEKIYIDGSLHPVKVGMRRIKLSKTYTLHGTDFSSFPLYDTSGPYSDPSVTIDLHKGLPSTRDFWQKNRTDIEVCPGKNPSPMNNRTPVRAKQGKSVTQMHYARKGIITPEMEYVAIRENQQLEEWIERFSSNGSSVKPVTPEFVRDEIAKGRAIIPANINHPELEPMAIGRNFRVKINANIGNSALASSISEEVEKSVWACRWGADTVMDLSTGKNIHQTREWILRNSPVPIGTVPIYQALEKVGGKAEELNWNIYRDTLIEQAEQGVDYFTIHSGILLDFLPAAQRRTTGIVSRGGSIIAKWCRAHKQENFLYSHFDDICDILRSYDIAISIGDALRPGSIADANDEAQFSELKTLGELTLKAWKYDVQVMIEGPGHVPLNLVEENMRKQLEYCHEAPFYTLGPLVTDIAAGYDHVNSAIGGTLLASLGCAMLCYVTPKEHLGLPDKNDVREGVIVHKLAAHAADIAKGSPSALLHDKLMSSARYSFAWNDQFNLSLDPVKTRQVHAESSQQNTGDGTDDHFCTMCGPDFCSMKKSQEVTGK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PYS1_PSEAI
Sequence: MARPIADLIHFNSTTVTASGDVYYGPGGGTGIGPIARPIEHGLDSSTENGWQEFESYADVGVDPRRYVPLQVKEKRREIELQFRDAEKKLEASVQAELDKADAALGPAKNLAPLDVINRSLTIVGNALQQKNQKLLLNQKKITSLGAKNFLTRTAEEIGEQAVREGNINGPEAYMRFLDREMEGLTAAYNVKLFTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQTPDSVRYALGMDAAKLGLPPSVNLNAVAKASGTVDLPMRLTNEARGNTTTLSVVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPVYEGATLTPVKATPETYPGVITLPEDLIIGFPADSGIKPIYVMFRDPRDVPGAATGKGQPVSGNWLGAASQGEGAPIPSQIADKLRGKTFKNWRDFREQFWIAVANDPELSKQFNPGSLAVMRDGGAPYVRESEQAGGRIKIEIHHKVRVADGGGVYNMGNLVAVTPKRHIEIHKGGK
What is the function of this protein?
Causes breakdown of chromosomal DNA as well as complete inhibition of lipid synthesis in sensitive cells.
What are the official names of this protein?
Pyocin-S1, Killer protein.
What is the protein family that this protein belongs to?
Belongs to the colicin/pyosin nuclease family.
Protein: CYSA1_AGRFC
Sequence: MEVKVSGITKQFDRFPALNDVSLDIRSGELIALLGPSGSGKTTLLRLIAGLEQPTQGQIFFGDEDASHRTVQERNVGFVFQHYALFRHMTVADNIAFGLKVRPSASRPPKAEIRRRVSELLDMVHLTGLEKRYPTQLSGGQRQRVALARAVAIEPKVLLLDEPFGALDAKVRKELRRWLREFHDRTGHTTVFVTHDQEEALELADRVVVMSQGKIEQVGTADDVYDTPNSPFVFSFIGESSSLPVTIRDGHVLFQGESIGINEGGTGEGELFFRPEDVVLTDEKDALYGKVTTCRRLAGTRIAEIDIANNGHEPYHLEIEVPLNAAVAVGAELRFRPTRWKVFGKK
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA 1, Sulfate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SIPL2_ORYSJ
Sequence: MATHHARRLPAAAAVLLLVLLAGGSAADDASSDDDAGVPPSPGCSNKFQLVKVKNWVNGTEGTIVVGLSARFGASVPRDIHEAQKTFAVLANPLDCCSNSTSKLTNYIAIAQRGECAFTAKAKIAQTGGAVGLLVINDNEELYKMVCSDNDTSINVTIPVVMIPQSAGKKMKGLLDQGARLEVQLYSPNRPVVDLSACFLWIMAIGTIVCASLWTEFVACEQVDERYNQLTRKDGPNSGTTNREDKEIFEISAKGAIVFILVASVFLLLLFYFMSSWFVWLLIVLFCIGGIEGMHVCLVTLLTRICKDCGQKTVQLPFFGEVLTLSVLIVPFCTIFAILWAVYRHASFAWIGQDILGICLMITVLQMARLPNIRVASALLSAAFVYDVFWVFISPLIFHESVMIAVARGDNSGEAIPMLLRIPRFFDPWGGYDMIGFGDIIFPGLLVAFSYRFDRASKRGLFNGYFLWLTVGYAVGLFLTYLALFLMDGHGQPALLYLVPCTLGLIVILGWFRGELHDLWNYGRSQTENLVDEP
What is the function of this protein?
Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane.
What are the official names of this protein?
Signal peptide peptidase-like 2, OsSPPL2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22B family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: DAUA_ECOLI
Sequence: MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQMAHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL
What is the function of this protein?
Responsible for the aerobic transport of succinate from the periplasm to the cytoplasm at acidic pH (PubMed:23278959).  Can transport other C4-dicarboxylic acids such as aspartate and fumarate (PubMed:23278959).  May also play a role in the regulation of C4-dicarboxylic acid metabolism at pH 7, via regulation of expression and/or activity of DctA.  May act as a co-sensor of DcuS (PubMed:23278959).
What are the official names of this protein?
C4-dicarboxylic acid transporter DauA, Dicarboxylic acid uptake system A.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G3P_CHLT2
Sequence: MRIVINGFGRIGRLVLRQILKRNSPIEVVAINDLVAGDLLTYLFKYDSTHGSFAPQATFSDGCLVMGERKIRFLAEKDVQKLPWKDLDVDVVVESTGLFVNRDDAAKHLDSGAKRVLITAPAKGDVPTFVMGVNHQQFDPADVIISNASCTTNCLAPLAKVLLDNFGIEEGLMTTVHAATATQSVVDGPSRKDWRGGRGAFQNIIPASTGAAKAVGLCLPELKGKLTGMAFRVPVADVSVVDLTVKLSSATTYEAICEAVKHAANTSMKNIMYYTEEAVVSSDFIGCEYSSIFDAQAGVALNDRFFKLVAWYDNEIGYATRIVDLLEYVQENSK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX2B_ARATH
Sequence: MMGSENDEESHLHSSKEEMEKLFLREDGDPLTKSNVNGDKSNSNYRSAMSTLFDSRHPSIVVTPADSDPLFAPPSYYSESRSPRSKPNGGDRVSSYLEPPSYADVIFSPFDDISEINGSEDGHSQSSDSLSRSPSSLSSDYIKITVSNPQKEQEATNSMIPGGSTYITYQITTRTNLSDYGGSEFSVRRRFRDIVTLADRLAESYRGFCIPPRPDKSIVESQVMQKQEFVEQRRVALEKYLRRLVAHPVIRNSDELKVFLQAQGKLPLATSTDVASRMLDGAVKLPKQLFGEGGGASSVEVVQPGRGGRDFLRMFKELRQSVSNDWGGSKPPVVEEDKEFLEKKEKMYDLEQQIINASQQAESLVKAQQDMGETMGELGLAFIKLTKFENEEAVFNSQRARANDMKNLATSAVKASRFYRELNSQTVKHLDTLHDYLGLMMAVQGAFADRSSALLTVQTLLSELSSLEARAEKLEVASSKVFGGDKSRIKKIEELKETIKVTEDSKNVAIREYEQIKENNWSEVERLDRERRADFLNMMKGFVANQVGYAEKIANVWTKVAEETRQYDRESS
What is the function of this protein?
Plays a role in vesicular protein sorting.  Acts at the crossroads between the secretory and endocytic pathways.  Is involved in the endosome to vacuole protein transport and, as component of the membrane-associated retromer complex, is also involved in endosome-to-Golgi retrograde transport.
What are the official names of this protein?
Sorting nexin 2B.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPZ1_RAT
Sequence: MADSDSSSEMPAHSPSPSPIPCAKQKPPNTGITISLLEIGSLPTFCCSSFSEPNNNMCPIRKQGKVQKFSNLLKDVKDVLKNIAGFEEKTTDGDPFDDTYIPEDLSELNIRGFDKRNKLRFKDDLFIHFDPERENTMRQEMLFKSHSAKNMVQKFARDLCNSEEKRGCDGVQLNAKRRRTGSVHIRGEYRKLRNNMEQLLQEADHWSKQHNELSELMRSYQECHKEIKDIVDCSRVCSQTQNNNEVPSKQKLEEQVKKLSQDTHSLHLIAALLENECQILQQRVDILRELHLHEAGPGHEKPLQTSGEQDKKCGEQDKKCGEQDKKCGEQDKKCPKLAEAEKMDGSKHTMKTTEGTITRKPKIFRCPNDCLTKKARNNRFNARVAKKSLVGKRRTISSFR
What is the function of this protein?
Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif.  May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis (By similarity).
What are the official names of this protein?
Spermatogenic leucine zipper protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PXMP4_MOUSE
Sequence: MAAPPQLQALLQAVNKLLRQRRYHAALAVIKGFRNGAVYGVKIRAPHALVMTFLFRSGSLREKLQAILKATYIHSRNLACFVFAYKSLHALQSHVQGETHQMHSFLAAFIGGLLLFGENNNINSQINMYLTSRVLYALCRLGVEKGYIPALKWDPFPLHTAVIWGLVLWLFEYHRPTLQPSLQSSMTYLYEDSNVWHDLSDFLIFNKSHPSK
What are the official names of this protein?
Peroxisomal membrane protein 4, 24 kDa peroxisomal intrinsic membrane protein.
What is the protein family that this protein belongs to?
Belongs to the peroxisomal membrane protein PXMP2/4 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Multi-pass membrane protein.