PharMolix/UniProtQA huggingface dataset:
Protein: SEC2_SCHPO
Sequence: MPDVSNVRVKPNQHPYEKEVNGKLMSQEEILSQKLVAAIERQAALDDKYATEVHRNEALSERIRELEAKLSAKKSFDEELVKFHNLEEKLQLTETKCRNAESEKSRVENELEDLTSSLFEEANRMVANARKETVASEKRVNQLKKQLVDAETLLSSTQHQLTELKDVMHSMSDSHEQNNALHPPLSRTTSFVADNVSVGSFASSTSGLDILTGTSARESLDAKEISSDKHLNISGERPATFPNPTFIEGSDERRSASSLGHRTNNNQNQLIRFSTQIRSSSTSPPRSPLIISDSPSSSIIHNPHPTHPSASAMNYMNPCFLEFHAFFNYPMKFARSRSAYSTSANYSNTPPRNTVTPSTARSSTLSQNPSSSSNSIPLISRNLRDFSFFKRCLEEDIEPTLRLDHASGLSWLTRRSVFTAILESSLIINPLHSTSLLSSQPCSLCGFNRTQPLRQFEFRSRPDSTSHASCTYCVARLRSVCNFVAFLHQICKGVWSSCSLEKAWDECLKKREAMFLSRVGLAKELEG
What is the function of this protein?
Guanyl-nucleotide exchange factor for ypt2.  Catalyzing the dissociation of GDP from ypt2 and promotes the binding of GTP (By similarity).
What are the official names of this protein?
Rab guanine nucleotide exchange factor sec2, GDP-GTP exchange factor sec2.
What is the protein family that this protein belongs to?
Belongs to the SEC2 family.
Protein: CRCB_NITEU
Sequence: MWKPILAIALGSTLGGLLRWGLGLKLNNLFPDVPPGTLVANLIAGYVVGVAIAFFAHMPNLSPEWRLLVITGFCGGLSTFSTFSAEIVSLLQRGLYAWAMSAIAVHVAGSLIMTLAGIATVTWFKSS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y279_ECOL6
Sequence: MRGCTLLLFSEAPFLREQEVAVITAYRNVFIQDDPGMHFRWVIRNAEGQRRWRCRNSEPDAGKVLNTRLASDGPLRQ
What are the official names of this protein?
UPF0401 protein c0279.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: DEF2_BRACM
Sequence: QKLCERPSGTXSGVCGNNNACKNQCIR
What is the function of this protein?
Possesses some antifungal activity sensitive to inorganic cations and antibacterial activity against B. megaterium.
What are the official names of this protein?
Defensin-like protein 2, Cysteine-rich antifungal protein 2, AFP2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: NHAB_SALEP
Sequence: MEISWGRAMWRNFLGQSPDWYKLALLVFLIVNPFIFLANPFIAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVIIGMTSAAHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMVLSLAFCVAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRGEENDMLDDSHIDPHYKTVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLVCGLLTCMLVEKMRWFGYGETLPEKVRDVLQQFDDQSRKKRTRQDKIKLIVQAVIGVWLVTALALHLAEVGLIGLSVIILATALTGVTDEHAIGKAFTESLPFTALLTVFFSIVAVIIDQHLFAPIIQFVLQASEHAQLTLFYLFNGLLSSISDNVFVGTIYINEAKAAMENGAISLKQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLTLIGLLCVEFTLAPATEWMTQAGWLATLS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUDC1_DANRE
Sequence: MALPNCSLNVNRELVDPNFESYRLSLDSIPTYNIELDAAVAEVKLKDSQYTLDHVRAFGMFNYLQIDPWYEDSVYFVDSKGRVLNLTVTLDTALGKPREMFHFESDSSSPEALCASLSLTSATWAALSDGNGKLTLLRTSKRGESSHLKWEPMFSESLGDPFIIVHSLAHVHSNVHTVEVLLLRVQKDPSDTKGSGFSVSLEWITVDNSAGQGESEEKKYAVRKRRVMKGKSVPHYAAVEPQGKGVIVASEKPFAFTEVDGLPLEEPPVQDMEVGNSDPIYFWQQTEEDVTLCVRLPEGTTKDDIRFKLTVDCLRVRVGDYAPLLDGQLFAPVDPEASTWTMNDDKSLEVSLQKRSEGPLWSEVVLGDRRGEYLMNDEQKSQLQQRLSYLTSEDLNPNPEKDKPPCNAQELEDCDMSPEDSSTLMRFDGATLKPNNVVSLGSNQFLFSVHIDPSETPAFCLRHDVDALLWQPRPDQDNNIWEHISTFNALGYVQASKRDKKFATCAPNFSYAALCECLRRVFIYRQPSPVDTVLFNRKQGRQVGQVAKQQVANLDTNDPVLGFRATNERLFVLTLNNLFVLKVNN
What are the official names of this protein?
NudC domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YPE1_NPVLD
Sequence: MSGCWARRARPWIRWRTSKVSCARCKNAWARRRARRYTRPPPSRRLCTGSRRVWSRCAPSCARSRNA
What are the official names of this protein?
Uncharacterized 7.9 kDa protein in PE 5'region, ORF1.
Protein: RS15_BACC2
Sequence: MALTQERKNEIIAQFRTHETDTGSPEVQIAVLTEQINTLNEHLRTHKKDHHSRRGLLKMVGKRRNLLTYLRNSDITRYRELITKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SYNC1_ARATH
Sequence: MADEIVPPATQLAAVSLENDGSTVQRAQFSNRVLIRTILDRPDGGAGLAGQTVRIGGWVKSGRDQGKRTFSFLAVNDGSCPANLQVMVDPSLYDVSNLVATGTCVTVDGVLKVPPKGKGTQQQIELNVVKVIDVGTVDASKYPLPKTKLTLETLRDVLHLRSRTNSISAVARIRNALAFATHSFFQEHSFLYIHTPIITTSDCEGAGEMFQATTLINYTERLEQDLIDNPPPTEADVEAARLIVIERGNVVAELKAAKASKEAITAAVAELKIAKETFAHIDERSRLRPGLPKKDGNIDYSKDFFGRQAFLTVSGQLQVETYACALSNVYTFGPTFRAENSHTSRHLAEFWMVEPEIAFADLEDDMNCAEAYVKYMCNWLLEKCYADMELMAKNFDSGCIDRLKLVASTPFGRITYTKAIELLEEAVAKGKEFDNNVEWGIDLASEHERYLTEVLFQKPLIVYNYPKGIKAFYMRLNDDEKTVAAMDVLVPKVGELIGGSQREERYDVIKKRIEEMGLPIEPYEWYLDLRRYGTVKHCGFGLGFERMILFATGLDNIRDVIPFPRYPGKADL
What are the official names of this protein?
Asparagine--tRNA ligase, cytoplasmic 1, Asparaginyl-tRNA synthetase 1, AsnRS 1, Protein EMBRYO DEFECTIVE 2755.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL331_CUTAK
Sequence: MAKKSGDVRPKITLACTECKERNYITKKNRRNNPDRMEMAKFCPRCRKHTAHRETR
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SECY_PYRAB
Sequence: MGARDIIYAIEKWFPEVERPKKHVPLKEKFMWTGLALILYYVLAEIPVYGIPERIQDYFQFLRVVLAGRNGSILTLGIGPIVTAGIILQLLVGSEIIKLDLANPEDRRFYQALQRVFSVFMCFLEAAIWVLGGAFGRVGVDVTYAIAALMILQLAFGGIILIVLDELVSKWGIGSGISLFIAAGVSQRILTRSLNPLTDPNIIDPLTGKPAIVGAIPYFIQHILKGDLKGALYRGGTAPDMMAVIATIIVFLVVVYFESMRVEIPLGYRGVTIRGRYPIRFLYVSNIPIILTFALYANIQLWARVLDRLGHPWLGTFDPTTGNPVGGFVLYVIPPRSIFTVIDNPVRALVYLILTVISSLIFGFLWVELTGLDARTIARQLQRAGLQIPGFRRDPRTLERVLQKYIPYVTFWGSLTVALIAVLADFLGALGTGTGILLTVGILYRFYEEIAREQISEMFPALRRFFAT
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY, Protein transport protein SEC61 subunit alpha homolog.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF1_BACAH
Sequence: MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMC_MYCGE
Sequence: MVFLKRFRAYGFKSYADEITIDFTHSMTGIVGPNGSGKSNVVDALKWVLGERSMKHLRSKSGDDMIFFGSKDKPASKLAEIELTFDNSNRLLHDSRKEISVMRRVYRGSGQSEYFINSNPATLKEISGIFADIGLEKGSLGIISQGSVSWFVEAKPEERRKIFEDASGIGRYTKRKEEVVNQLNRTLINLKQVSVVLNELKKDLKKLTLQAEKAQQFIRVKNELKELELAVLVGEYLQAQTELDKFNFQINSSEHDFKIHEPQLELLEEQIVIFNSRFHSADMQSNELQKELQDIYQKINELEQRKVIIDVQLRQGFSQKDEKQKAAALKKLILVDQTQLDGFENQLSNSKTTITDLEKLINEQKSLVDQIKLQIEKNTADLIYQRSLKTIIELQTNELKKTNNANILVKNANALTGILNTLGTFLKFDKQYEKAILKALGKSIGYLVVNNNNAAIQAIDFLVKNEIGKVTFLPLDDVASDTKITNEHMEILKQLDGFLGVCSDHVKCDPLFQPVVNTLLAQVIIAKDLNSAINLSNYTYKLYRIVTLDGETVYAGGIINGGFEKTNLSDGYLSSASLDNEQNINKLENNERELKKELTELEVKLDEMNRKLKYEELLQAKFIERIVQIKKIILELKMEYEQLTNTTFDGKKAVASEAELIHSLNSAWAKRDEINSKLKLNQELKLQLAKTIKQSEEKIVDLRALLDEQRAKLVSAREGKIRFENTIQNITEKINSVYKMTMEFAIANHNKPVKLSSMQAHNKIAKLQNQLNEMGVINMESIAEISEKQKRFDDINAEYESAQQAVENLQKAITEIDEIASNEFDQLIQKLNQELPKTFKYLFGGGSCQIRYTDPSNVLVSGIDVFANPPGKNIANLMLLSGGEKTLVALSVLFSILKVSAFPLVILDEAESALDPANVERFANIIKTASKNTQFLIITHRQGTMMKCDMLLGAAMQTKGVTKTFAVELENAEKYVSENDSN
What is the function of this protein?
Required for chromosome condensation and partitioning.
What are the official names of this protein?
Chromosome partition protein Smc, Protein P115 homolog.
What is the protein family that this protein belongs to?
Belongs to the SMC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRY2_HUMAN
Sequence: MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTIAANS
What is the function of this protein?
In the ileum, may be involved in defensin processing, including DEFA5.
What are the official names of this protein?
Trypsin-2, Anionic trypsinogen, Serine protease 2, Trypsin II.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TIAF1_HUMAN
Sequence: MSSPSSPFREQSFLCAAGDAGEESRVQVLKNEVRRGSPVLLGWVEQAYADKCVCGPSAPPAPTPPSLSQRVMCNDLFKVNPFQLQQFRADPSTASLLLCPGGLDHKLNLRGKAWG
What is the function of this protein?
Inhibits the cytotoxic effects of TNF-alpha and overexpressed TNF receptor adapters TRADD, FADD, and RIPK1.  Involved in TGF-beta1 inhibition of IkappaB-alpha expression and suppression of TNF-mediated IkappaB-alpha degradation.
What are the official names of this protein?
Putative TGFB1-induced anti-apoptotic factor 1, 12 kDa TGF-beta-1-induced antiapoptotic factor.
What are the subcellular locations of this protein?
[Isoform TIAF1]: Nucleus.
Protein: PLYA_ASPNC
Sequence: MTNFKWIVAAAGLLSGQVLAAPTATSTHAKRATVSDAAFGYASLNGGTTGGAGGTTTTVSSYAAFTSAVSGDDAKVVYVDGTIKQTADQVKIGSNTSIIGKDANAILEGFGVLVKEKENVIIRNLGVSKVLADNGDAIGVQYSNNVWIDHCDVSSDRDHDKDYYDGLIDITHGSDYVTVSNTFIHDHWKASLVGHSDSNEDEDSGHLTVTYANNYWYNINSRAPSFRFGTGHVYNSYYLDVSDGINTRDGAQLLVESNQFVDSKKALYSTDDGYAVSNDNDFGDSENTAEEGTLTSMPYDYTLLGSANVKAAVVGTAGQTLTF
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BDLF2_EBVA8
Sequence: MVDEQVAVEHGTVSHTISREEDGVVHERRVLASGERVEVFYKAPAPRPREGRASTFHDFTVPAAAAVPGPEPEPEPHPPMPIHANGGGETKTNTQDQNQNQTTRTRTNAKAEERTAEMDDTMASSGGQRGAPISADLLSLSSLTGRMAAMAPSWMKSEVCGERMRFKEDVYDGEAETLAEPPRCFMLSFVFIYYCCYLAFLALLAFGFNPLFLPSFMPVGAKVLRGKGRDFGVPLSYGCPTNPFCKVYTLIPAVVINNVTYYPNNTDSHGGHGGFEAAALHVAALFESGCPNLQAVTNRNRTFNVTRASGRVERRLVQDMQRVLASAVVVMHHHCHYETYYVFDGVGPEFGTIPTPCFKDVLAFRPSLVTNCTAPLKTSVKGPNWSGAAGGMKRKQCRVDRLTDRSFPAYLEEVMYVMVQ
What is the function of this protein?
Rearranges cellular actin to increase intercellular contacts and thereby promote virus cell-to-cell spreading.  Induce the outgrowth of long, branched plasma membrane fronds to create intercellular network for virion traffic.  The fronds are actin based and RhoA-dependent (By similarity).
What are the official names of this protein?
Protein BDLF2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BDLF2 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein.
Protein: SSPK_BACP2
Sequence: MRNKAKGFPNQVNHKFEGEPGATDAYASKRPNGETNTRPQERMRASGKR
What are the official names of this protein?
Small, acid-soluble spore protein K, SASP K.
What is the protein family that this protein belongs to?
Belongs to the SspK family.
What are the subcellular locations of this protein?
Spore core.
Protein: MSCL_VIBCH
Sequence: MSLLKEFKAFASRGNVIDMAVGIIIGAAFGKIVSSFVADIIMPPIGIILGGVNFSDLSFVLLAAQGDAPAVVIAYGKFIQTVVDFTIIAFAIFMGLKAINSLKRKEEEAPKAPPAPTKDQELLSEIRDLLKAQQDK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: F181B_MOUSE
Sequence: MAVQAALLSSHPFIPFGFGGSADGLVSAFGSLDKGCCFEDDESGASAGALLSGSEGGDVREATRDLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGTAPPRPASPSAADAPAKRPPGAPTVATPAHCKAAPRREATQAAAAASLQSRSLAALFDSLRHIPGGAETAGGAEAVSVPGLGAASAVGDGAGTAVSSVAPGTRKVPLRARNLPPSFFTEPSRVGCGGASGVPSGQGVSLGDLEKGAEAVEFFELLAPDFGSGNDSGVLMAADPLDPFPAGATVLRGPLELESGPFEQPAMVGNLLYPEPWNTPSCPQTKKPPVAGVRGGVTLNEPVRLLYPTALDSPGGEDAPALSSFTPFFPDCALPPPHQVSYDYSAGYSRAVYPSLWRPDGVWEGASGEEGGHPD
What are the official names of this protein?
Protein FAM181B.
What is the protein family that this protein belongs to?
Belongs to the FAM181 family.
Protein: QUED_METTH
Sequence: MVMMKIVINGIHANLRFSAAHMIPEHESCGCIHGHSYIVDVKVEGKRSGKHGFVADFKDVKDIVRRICSEFDHKLLIPLRNPLINFTSTTRTVKFEIAGKKYSIPEEDCCLMDLESSSAEELSRYFAATLFKELSSKYDISSVEVCVNEGIGQGAIYTISR
What is the function of this protein?
Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde.
What are the official names of this protein?
Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase, CPH4 synthase, Archaeosine biosynthesis protein QueD.
What is the protein family that this protein belongs to?
Belongs to the PTPS family. QueD subfamily.
Protein: RBFA_SYNWW
Sequence: MSKRRQERMSVEIMRVLSQIIQEEIKDPRIEFKNLSITRIDLSNDYSHARVNISILGDEIQREEAMKALQKAKGYIRSALAQQLKVRHAPELEFRLDRSIEHGIRISSLLEEIKEEAKGSNE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_SALEP
Sequence: MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMVKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SHAN1_MOUSE
Sequence: MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGPQGTRGRGSGAPGNLASTRGLQGRSMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPPGAGLTVPPALLRANSDTSMALPDWMVFSAPGASSSGTPGPTSGSQGQSQPSAPSTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPRDGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQGEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLEEVANRSQEGRQESRSDKAKRLFRHYTVGSYDSFDAPSLIDGIDSGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKASQQAKRLPPPAISLRSKSMTSELEEMVSPWKKKIEYEQQPAAVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRSQPSYDRPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPAPSSSGRLTPSPRGGPFNPGSGGPLPASSPSSFDGPSPPDPRSGGREKSLYHSGALPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTSGAPSPSHHSSSGGSSGPAQAPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGSLPPASSPTSPALPRSEPPPAGPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPDGAGGGGSSPSPAPATSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDSGLGPGAPPGPRLRHSKSIDEGMFSAEPYLRLESGGSSGGYGAYAAGSRAYGGSGSSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGVTPQPPPRPPSPRYDAPPPTLHHHSPHSPHSPHARHEPVLRLWGDPARRELGYRAGLGSQEKALTASPPAARRSLLHRLPPTAPGVGPLLLQLGPEPPTPHPGVSKAWRTAAPEEPERLPLHVRFLENCQARPPPAGTRGSSTEDGPGVPPPSPRRVLPTSPTSPRGNEENGLPLLVLPPPAPSVDVDDGEFLFAEPLPPPLEFSNSFEKPESPLTPGPPHPLPDPPSPATPLPAAPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGAPAAPGDPPAPGPPAPAAPAPPAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGNTGGVAGGGAGVASGTELLDTYVAYLDGQAFGGSGTPGPPYPPQLMTPSKLRGRALGTSGNLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALSACSGPSTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLSQPQASALATVKASIISELSSKLQQFGGASTAGGALPWARGGSGGSTDSHHGGASYIPERTSSLQRQRLSEDSQTSLLSKPSSSIFQNWPKPPLPPLPTGSGVSSSTAAAPGATSPSASSASASTRHLQGVEFEMRPPLLRRAPSPSLLPASDHKVSPAPRPSSLPILPSGPLYPGLFDIRSSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKPLGFWTKFDVADWLEWLGLSEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLER
What is the function of this protein?
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton.  Plays a role in the structural and functional organization of the dendritic spine and synaptic junction.  Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function (By similarity).
What are the official names of this protein?
SH3 and multiple ankyrin repeat domains protein 1, Shank1.
What is the protein family that this protein belongs to?
Belongs to the SHANK family.
What are the subcellular locations of this protein?
Cytoplasm. Synapse. Postsynaptic density. Note=Colocalizes with alpha- latrotoxin receptor 1.
Protein: TEST_MOUSE
Sequence: MGARGKTLVPLLVVVATAAMALQSTYLQVDPEKPELQEPDLLSGPCGHRTIPSRIVGGDDAELGRWPWQGSLRVWGNHLCGATLLNRRWVLTAAHCFQKDNDPFDWTVQFGELTSRPSLWNLQAYSNRYQIEDIFLSPKYSEQYPNDIALLKLSSPVTYNNFIQPICLLNSTYKFENRTDCWVTGWGAIGEDESLPSPNTLQEVQVAIINNSMCNHMYKKPDFRTNIWGDMVCAGTPEGGKDACFGDSGGPLACDQDTVWYQVGVVSWGIGCGRPNRPGVYTNISHHYNWIQSTMIRNGLLRPDPVPLLLFLTLAWASSLLRPA
What is the function of this protein?
Could regulate proteolytic events associated with testicular germ cell maturation.
What are the official names of this protein?
Testisin, Serine protease 21, Tryptase 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: RL10_STAAR
Sequence: MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQLREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKDHEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQKEENAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: SWT21_YEAS6
Sequence: MEKKVICQDIFWSCDGTSFVSVHNDFGIRQYLVPEESNTDKLNRNLLLPFTRFFRNQSIVSCAIDPFYTLYNENSDRLAGDRIVVGGKNFPLQLYSLMDGQCILSYDTMNKINGEYETVYSVKIDVESRVYTGSCRNKVAIYDKSRRDAVWMNQSTKKASKGRQSIISCFEEQPMGGQALSRGSLLCGSYANEMFQVDCRHQRLERLNYTRTVAGGIVQILTSDNGRYVYVVRRNSDAISIYDRRNLQHELNVLRLPFRIHHNSAKLKAYIDTAYGLSMGTPQGTILNWGRDLVEFGGVPSHNSVEDPLITSIPPESEWRTNLDSTIPATVVKNCPGDPELFALSHGGTISLCRFGG
What is the function of this protein?
Involved in mRNA splicing.  Helps to stabilize the U1 snRNP-5' splice site interaction (By similarity).
What are the official names of this protein?
Protein SWT21, Synthetic With TGS1 protein 21.
What is the protein family that this protein belongs to?
Belongs to the SWT21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BUD32_ENTBH
Sequence: MILITSGAEAEIYESENMIIKRRVKKNYRIDELDSMLNKTRTKREVNIIKKLNALNIPSPMFYTTNKYDIVMEKIKGIPVKNILNNESLTSNQFLNKICAKTHKDILIEIGNIVYAMHNNNIIHGDLTTLNFIYSDKIHIIDFGLSFYSNKDEDKAVDLYLFEKSLISVHNEEFVSYFYSGYIVNETLNKKLLEIRKRGRKRE
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.
What are the official names of this protein?
EKC/KEOPS complex subunit BUD32, Atypical serine/threonine protein kinase BUD32.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome, telomere.
Protein: RBL_SCHTR
Sequence: SVGFKAGVKDYKLTYYTPEYQPQDTDILAAFRVTPQPGVPSEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIDAVPGEDNQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLALYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDYTEIDANRGIYFTQSWVSTPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLARQGATIIRNASKWSPELAAACEVWKEIKFEFPAVDTLDKKKG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.