PharMolix/UniProtQA huggingface dataset:
Protein: SYI1_OCEIH
Sequence: MDYKQTLLMPKTAFPMRGNLPNKEPERQKKWEETNQYAKTLERTKGRPLFVLHDGPPYANGDIHIGHALNKVLKDFIVRYKSMTGYHAPYIPGWDTHGLPIETALTKKKKIKRKEMDIAAFRKLCEEYALGQINNQREQFKQLGVRGDWDNPYITLTKDYEASQIKVFGDMARKGYIYKGLKPVYWSPSSESALAEAEIEYQDKRSPSIYVAFEVKGGQALLSGGEKFIIWTTTPWTLPANLGISLHADLTYIVVQVGEEKYIIAEALFDDVSESLGWENPQVLQSFKGKEAEGIEAQHPFYDRTSLVMLGEHVTTDAGTGCVHTAPGHGEDDFYVSRSYGIDAFCPVDEKGVFTQEAPGFEGLFYDEANKIITEKLDASGALLKLEFITHSYPHDWRTKKPTIFRATSQWFASIKDFRVDILEEIKQVNWYPHWGETRLYNMVRDREDWCISRQRAWGVPIPVFYGEDGTPIITDETINHVSELFREHGSNIWFEKEAKELLPEGFTSEHSPNGNFAKETDIMDVWFDSGSSHEGVLLNRQNHQRPANVYLEGSDQYRGWFNSSLSTSVAVTGKAPYKAVISHGFVLDGNGRKMSKSLGNVIVPSKVQKQLGSDILRLWVSSVDYQADVRISDDILKQTSESYRKIRNTFRFLLANLADFNPNTDRVKEENMEEVDRYMVHRLQNVLAEAHKNYNQYEFAPVFQQIHHFCSVDLSSFYLDFAKDILYIEAKDHPRRRSIQTGYYEVLTSLVKLIAPIIPHTAEEVWEYIPEPEAESVHLTDIPEARDVAINEQTVDKWNHFMKIRDDVLKALEEARSEKVIGKSLEAKISIAAKDEGTKKVLDEMEHLHQYFIVSEAVIVDTLTDAKEGNVVNVQVEVHPGETCDRCWVSSETVGENKNHPSLCSRCADVVTKHYAD
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase 1, Isoleucyl-tRNA synthetase 1, IleRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_SHIB3
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVGIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFSRSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_STAA8
Sequence: MARFRGSNWKKSRRLGISLSGTGKELEKRPYAPGQHGPNQRKKLSEYGLQLREKQKLRYLYGMTERQFRNTFDIAGKKFGVHGENFMILLASRLDAVVYSLGLARTRRQARQLVNHGHILVDGKRVDIPSYSVKPGQTISVREKSQKLNIIVESVEINNFVPEYLNFDADSLTGTFVRLPERSELPAEINEQLIVEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: GATB_BEII9
Sequence: MNTHVKPSKLIKGATGDWEIIIGLEVHAQVTSRSKLFSGASTQFGAEPNSNVSLVDAAMPGMLPVINEECVAQAVRTGLGLKAQINLRSVFDRKNYFYPDLPQGYQISQYKSPIVGEGIVIVDVSPTEQIEVGIERLHLEQDAGKSLHDQSATDSFVDLNRSGVALMEIVSKPDMRSADEARAYVSKLRTILRYLGTCDGNMEQGSLRADVNVSVRRPGEPFGTRCEIKNVNSIRFIGQAIETEARRQIGILEDGGVIDQETRLFDPGKGETRSMRSKEEAHDYRYFPDPDLLPLEFDQAYVDGLASALPELPDAKKARFMNDYGLPAYDAGVLVADKETADYYETTVNYNGVKRDPKLVANWVTGDVAAYANSVGLPVSQTHLTPAQIATLVDLISEEVISGKIAKDVLAILINEDKAGDPRTIVEARGLKQVTDTGAIEAAVDAIIAANPDKVAQAQAKPTMLGWFVGQVMKQTGGKANPQAVNEILKAKLGI
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: PANC_BURMS
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDQYPRTLQDDIEKLQKENVYVLFAPTERDMYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIIAAETVRDADGLALSSRNRYLSEAERAEAPELAKTLAQVRSAVLGGERDLAAIEQRALAHLAARGWKPDYVSIRRRANLVAPSAAHIEAGEPLVVLTAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHR1_CAEEL
Sequence: MNGTLADQLQSHLANYGQPMVNSQRNEDPSMYMNGSAASVSHTNGSSSMGNDQKFPSYKRMAQRRKVPEGELCAVCSDLATGYHYGVASCNGCKTFFRRTIVSEQTFICQYNGNCDVNKNIRCACRHCRFNKCLLVGMDAKALQIPAIQNDRDRIGPTKKIKMSSGSDDEQATTPHRLQDQEIIDQLTQVEGLCQELRRCIIPEVTGVTHALTSPCLLFETTDLKVDVSLTNTIFKELFPASMNDIRMWNIREMRICIEWAKTFDVYQRLNLFDQFALVRNFAFAFNLLNRVFYSPDHGPDKIVFQNGAFIMRQPQQQVQLSGCRPIYTRQMDEIMIPFRKLQLSVAEFATFKAALFFNPDALDLSPQAKQEVFEERNKYLGGLFTCITQKIGIPTGVQKYGSLLMMTASIQNILAQNEENMQVMELFKNWEVDPFVKELCMKRA
What is the function of this protein?
Orphan nuclear receptor which acts in concert with the insulin/IGF-1-like signaling (IIS) pathway during osmotic stress, perhaps in response to a ligand modified by the sulfotransferase ssu-1.
What are the official names of this protein?
Nuclear hormone receptor family member nhr-1.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UNG_CAMFF
Sequence: MTIDLAKVKIEDSWKEVLKDEFLSSYFLEIKFNLINALKNGKVYPPSNLIFNAFNLTPFDKVKVVILGQDPYHNEGEAMGLSFSVPKGVRVPPSLANIYKEIKDDLGIIEPNCGDLSYWAKQGVLLLNATLSVGARMANSHSNFGWQIFSDAVIKNISEKKTGVVFMLWGNYARAKANLIEANKHLVLTAAHPSPLARGAFFGSRHFSKCNNYLIKNGQTPIDWDLNNYTLN
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSEL_SALTI
Sequence: MNICVNSLYRLSTPQFHSLYSEEVSDEALALLFSAVENGDQNCIDLLCNLALRNDNLGHRVEKFLFDLFSGKRSGSPDIDKKINQACLVLHQIANNDITKDNTEWKKLHAPSRLLYMAGSATTDLSKKIGIAHKIMGDQFAQTDQEQVGVENLWCSARMLSSDELAAATLGLVQESPLLSVNYPIGLIHPTTKENILRTQLLEKMAQSGLSENEVFLINTGDHWLICLFYKLAEKIKCLIFNTYHDLNENTKQEIIEAAKITGISENEDIDFIETNLQNNVPNGCGLFCYHTIQLLSNAGQNDPATTLREFAENFLTLSVEEQTLFNTQTRRQIYEYSLQ
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protease targets the host cell ubiquitin pathway by acting as a deubiquitinase in infected host cells (By similarity).
What are the official names of this protein?
Deubiquitinase SseL, Deubiquitinating enzyme, DUB, Deubiquitinating protease, Salmonella secreted effector L.
What is the protein family that this protein belongs to?
Belongs to the peptidase C79 family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion system 2 (SPI-2 TTSS), and delivered into the host cytoplasm. In phagocytic cells localizes to the Salmonella-containing vacuole (SCV). In epithelial cells localizes to the Salmonella-containing vacuole (SCV) and to the Salmonella-induced filaments (Sifs), which are tubular membrane extensions from the SCV that are formed at late stages of infection (By similarity).
Protein: PROA_MYCS2
Sequence: MSVEAQSRSGAVDTQEPADLREQVHSAARRARVAARTLATLSAEAKNRALHAAADSVLANVDAVLAANAADVDAARQGGTPEAMIDRLALNPQRVDGIAAGLRQVAALPDPVGEVLRGKTLPNGLQLRQQRVPLGVVGMVYEGRPNVTVDAFGLTLKSGNAALLRGSSSAARSNQALVDALRSALAEEGLPLDAVQLLPSQDRASVTHLIQARGLVDVVIPRGGAGLIDAVVRDAQVPTIETGVGNCHVYVHSSADIDMAEKILLNAKTRRPSVCNAAETLLVDRALTDTALPRLVKALQDAGVTVHADPTEDELRAEFLSMDIALAVVDGLDAAIDHINTYGTGHTEAIVTTDLAAAQRFTERVDAAAVMVNASTSFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIVWGDGQIRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_BRUA1
Sequence: MSRPSTPLLDKAPTPDRLRALPEQDLPQLAEELRTELIDAVSTTGGHLGAGLGVVELTVALHHVFNTPYDRIIWDVGHQAYPHKILTGRRDRIRTLRQAGGLSGFTKRAESEYDPFGAAHSSTSISAGLGMAVASELSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLVSGRTYRSVREAAKQVAQKLPKFLQDKARKSEEYARAFFTGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDTQKGPVLIHVVTQKGKGYAPAEAAADKYHGVNKFDVITGKQAKPPANAPSYTKIFGTSLIEEARHDDKIVAVTAAMPTGTGLDLFGEAFPKRVFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQVVHDVSIQNLPVRFPIDRAGLVGADGPTHAGSFDTGFLAALPGFVVMAASDEAELRHMVRTAAEYDEGPISFRYPRGDGVGVDLPERGSVLEIGKGRIVREGTKVALLSFGTRLQECLAAAEELGAAGLSTTVADARFAKPLDHDLIRRLAREHEVLVMVEEGAVGGFSSHVLQFLATDGLLDRGLKVRALMLPDIYQDHGKPDAMYAEAGLDRTGIVRTVFAALHRDELGHEALPTPFRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CBHB_EMENI
Sequence: MASSFQLYKALLFFSSLLSAVQAQKVGTQQAEVHPGLTWQTCTSSGSCTTVNGEVTIDANWRWLHTVNGYTNCYTGNEWDTSICTSNEVCAEQCAVDGANYASTYGITTSGSSLRLNFVTQSQQKNIGSRVYLMDDEDTYTMFYLLNKEFTFDVDVSELPCGLNGAVYFVSMDADGGKSRYATNEAGAKYGTGYCDSQCPRDLKFINGVANVEGWESSDTNPNGGVGNHGSCCAEMDIWEANSISTAFTPHPCDTPGQTLCTGDSCGGTYSNDRYGGTCDPDGCDFNSYRQGNKTFYGPGLTVDTNSPVTVVTQFLTDDNTDTGTLSEIKRFYVQNGVVIPNSESTYPANPGNSITTEFCESQKELFGDVDVFSAHGGMAGMGAALEQGMVLVLSLWDDNYSNMLWLDSNYPTDADPTQPGIARGTCPTDSGVPSEVEAQYPNAYVVYSNIKFGPIGSTFGNGGGSGPTTTVTTSTATSTTSSATSTATGQAQHWEQCGGNGWTGPTVCASPWACTVVNSWYSQCL
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
1,4-beta-D-glucan cellobiohydrolase B, Beta-glucancellobiohydrolase B, Exocellobiohydrolase B, Exoglucanase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOB_BUCAP
Sequence: MVYSYTEKKRIRKDFGKRPQVLDIPYLLSIQLDSFKKFIKIDPEGLHGLEAAFRSVFPICGYNGNSELQYVSYRLGDAIFDVKECQIRGATYSAPLRVRLRLVIYERDVLEPTVKDIKEQEVYMGEIPLMTNNGTFIINGTERVVVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPVTIILRALNYNTEEILNLFFEKNIFNINNNKIQLELVSERLRGETASFDIKKNGKIYVKKGRRITAKHIQELKKDKINSITVPVEYILGRIVSKNYLDPKTGETIILANTELSLEILTKLKNSSFFSIETLFTNDLDHGPYISETLRIDSSHDRISALMEIYRVMRPGEPLTKEATENLFENLFFSEDRYDLSSVGRMKFNRSLLRKKIEGVSTLNKEDIIDVIKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSVGDLDTLMPQDMINAKPISAAIKEFFGSSQLSQFMDQNNPLSEITHKRRISALGLGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYARTNSYGFLETPYRKVHNRLVTDEIHYLSAIEEGNYVIAQANTNIDKNNYFIDDLVTCRHKGESSLFNCNQVDYMDVSTQQIVSVGASLIPFLEHDDANRALMGANMQRQAVPTLKTDKPLVGTGMERAVAVDSGVTVVAKRGGIIQYIDASRIIIKVNEEETYTGEAGIDIYNLTKYTRSNQNTCINQKPCVKLREKINKNDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSEKVVQEDRFTTIHIQELSCISRDTKLGPEEISSDIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQIFTRDGVKKDKRALEIENMQLKKAKKDLTEEFKIFELSLFSRIKKTLVSFNIKEDFLNKLPYEKWFKIDIQDRNKKKEIEKLLQQHNQLKKEFEKKIEVKRRKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGIPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGNKINNMLKKQEKISNLKKFIQKAFDLGENLRQKVNLDDFSNEEILDLAKNLKKGMPISTPVFDGAQENEIKQMLKFSNLPTSGQISLFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELENE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: OBG_DESVH
Sequence: MRFVDEATINVRAGKGGNGCLSFRREKFIPRGGPDGGNGGDGGSVILRPTNRLLSLYDFRLQRNYEARNGQSGMGSQCDGRKGEDLVLELPLGTLVFEVDDEGHEQMIADLSDPDGVFVVARGGRGGKGNEHFKSSTMRAPRFAQKGEPGEERRLRLELKILADAGLLGLPNAGKSTFISRISAARPKIAAYPFTTLTPNLGVMIDEVDPDRRMVIADIPGLIEGAHTGQGLGHRFLKHVERTRFLVHILSIEDIDPENPWTGFDLINEELARFDEVLREREQIEVVNKIDLRTPEEVDALRQQAAQQGRRIFFISAMHGEGIEEVVDAMWRLRDTIDMHEPLVHLQEVEEEDEEFEDIEVVYTRE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSJ_SHIFL
Sequence: MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPVALAVTPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEFFCQSGKDFDSKLAELGGERLLDRVDSDVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLTGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTLIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANLETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: RL1_BACFR
Sequence: MGKLTKNQKLAAGKIEAGKAYSLKEAASLVKEITFTKFDASLDIDVRLGVDPRKANQMVRGVVSLPHGTGKQVRVLVLCTPDAEAAAKEAGADYVGLDEYIEKIKGGWTDIDVIITMPSIMGKIGALGRVLGPRGLMPNPKSGTVTMDVAKAVREVKQGKIDFKVDKSGIVHTSIGKVSFTAEQIRDNAKEFISTLNKLKPTAAKGTYIKSIYLSSTMSAGIKIDPKSVEEI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: METK2_MOUSE
Sequence: MNGQLNGFHEAFIEEGTFLFTSESVGEGHPDKICDQISDAVLDAHLQQDPDAKVACETVAKTGMILLAGEITSRAAIDYQKVVREAIKHIGYDDSSKGFDYKTCNVLVALEQQSPDIAQGVHLDRNEEDIGAGDQGLMFGYATDETEECMPLTIVLAHKLNAKLAELRRNGTLPWLRPDSKTQVTVQYMQDRGAVLPIRVHTIVISVQHDEEVCLDEMRDALKEKVIKAVVPAKYLDEDTIYHLQPSGRFVIGGPQGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDYTKVDRSAAYAARWVAKSLVKGGLCRRVLVQVSYAIGVSHPLSISIFHYGTSQKSERELLEIVKKNFDLRPGVIVRDLDLKKPIYQRTAAYGHFGRDSFPWEVPKKLKY
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase isoform type-2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
Protein: MED30_BOVIN
Sequence: MSTPPLAASGMAPGPFAGPQAQQAAREVNTASLCRIGQETVQDIVYRTMEIFQLLRNMQLPNGVTYHTGTYQDRLAKLQDHLRQLSILFRKLRLVYDKCNENCGGMDPIPVEQLIPYVEEDGSKDDRAGPPRFASEERREIAEVNKFQVNSKGTQPYLHMYPFSSKLPSHSGCRIPLSRIPCAVQNSNRRINS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 30, Mediator complex subunit 30, Thyroid hormone receptor-associated protein 6, Thyroid hormone receptor-associated protein complex 25 kDa component, Trap25.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 30 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_XANCP
Sequence: MSLTNEQIVDAIAEKSLMEVMELVKAIEEKFGVSAAAPVAAAAAGPAAVVEEQTEFTVVLTSPGANKVAAIKAVRGVTGLGLKEAKDLTEAGGILKEGVSKDEAEKIKKEMTEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: KCY_FUSNN
Sequence: MDNIIVAIDGPAGSGKSTIAKLIAKKFNFTYIDTGAMYRMITLYLLENNINFDDLKEIEKALKNINLDMQGDKFYLNDVDVSTKIREKRINENVSKVASIKIVRDNLVNLQRKISNNKNVILDGRDIGTVVFPNAKVKIFLVAAAEERARRRYNEFLEKKVEITYDEVLKSLKERDYIDSTRKESPLKKADEAIELDTTNLTIEDVINFISKKIEKVK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCYOX_HUMAN
Sequence: MGRVVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAIIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSAVQASGGLLGIYNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL
What is the function of this protein?
Prenylcysteine oxidase that cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine (PubMed:10585463, PubMed:11078725, PubMed:12186880).  Only active against free prenylcysteines and not prenylcysteine residues within prenylated proteins or peptides (By similarity).  Involved in the final step in the degradation of prenylated proteins, by degrading prenylcysteines after the protein has been degraded (PubMed:10585463).
What are the official names of this protein?
Prenylcysteine oxidase 1, Prenylcysteine lyase.
What is the protein family that this protein belongs to?
Belongs to the prenylcysteine oxidase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: KGUA_VIBPA
Sequence: MGKGTLYIVSAPSGAGKSSLISAMLERNPTYAMKVSVSHTTRNMRPGEEDGVHYHFVAKEEFETLIAKGDFLEYAEVFGNYYGTSRVWIEETLEKGIDVFLDIDWQGARQIREQMPKAKSIFILPPSNGELERRLNTRGQDSAEVIAKRMAEAKSEISHYSEYDYVIVNDDFDTALMDFKAILRAERLKEEKQAAKYKGMLDALLAE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_BURO1
Sequence: MTSATQFDNVSVVKRANVYFDGKCVSHTVLFPDGTRKTLGVILPCALNFGTDAPELMEVQAGKCRVKLDGSSEWQTYGAGESFSVPGKSRFDIEVLETLDYVCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: AROK_RHOE4
Sequence: MKPKAVLIGPPGAGKSTIGRRLAQALELELVDTDAEIERTTGRTIPEIFTHDGEPRFREIEESVVRDALQATDGIVSLGGGAILSDRTRELLQGHTVIYLEISVAEGLRRTGANNHRPLLAGGDPKVKYQELMRRRRPLYRRSATIRIRTDGRSPARVVGQLVSKLQDK
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_CHLPB
Sequence: MKRVVLFLLTNLAVIAVLSITARILGVDRFLTANGLNMGMLLAFAALIGFGGAFISLLMSKTMAKWSTRARVIERPGNQDEAWLVDTVRQLSKKAGLPMPEVAIFDGAPNAFATGASKSKSLVAVSTGLLQSMDRKQVAAVLAHEVAHVENGDMVTLTLIQGVVNTFVIFLSRALGYLVDNFLRGDNEESTGPGIGYWISSIAFEIVFGVLASIVVMYFSRKREFRADAGAAKLMGDRRPMIDALRTLGGLQAGQLPKEMAASGIAGGGMMALFSSHPPLESRIAALESATPPSTPTPSRRGS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_LEUCK
Sequence: MRHFLNINAIELDDVVDLVHRALAIKAGRSVIQSNLTVTNLFFENSTRTHSSFQMAENRLGYQQIDIDPQQSSMSKGESLTDTLKTLKAIGVDVAVIRHTVNNWYDQVLTATGHEIPHLINAGDGSGQHPSQSLLDLVTIYEQFNHFAGLNIRIVGDLAHSRVARSNAEILHHLGANMTFSGPKDWQPNDFGKFGQFVAIDDDWENLDVVIFLRVQHERITQTENQNFSTKQYHEQFGLNRVRYERLKAAAIIMHPAPVNRDVEIADELVEAPKSRIFEQMNNGVYARMAILEYTTEATHATH
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.