PharMolix/UniProtQA huggingface dataset:
Protein: NLGN3_MACMU
Sequence: RYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNKPVPQDTKFIHTKANRFEEVAWSKYNPRDQLYLHIGLKPRVRDHYRATKVAFWKHLVPHLYNLHDMFHYTSTTTKVPLRIPPTAPTSPAGPMARPGAPSGQPSHLPTATRMPRGPGTGTRMQGHSW
What is the function of this protein?
Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members.  Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins.  May promote the initial formation of synapses, but is not essential for this.  May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity).
What are the official names of this protein?
Neuroligin-3, Gliotactin homolog.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synapse. Note=Detected at both glutamatergic and GABAergic synapses.
Protein: AUPB_MARN1
Sequence: MKYNKTLALIPAILLAACGGGDKQSIDEKPRPGSMVYSFPMDGQADVSPKADIVLRFSHAITDDEATLQNKIILQSSGQSQPFTVTLIDSGKSLKLEPANPLATGEEFTVTFQEPLAAEGGRQITTPNATGDDGIQFATRGAYAGLAELANTADTFDIAWQVPASDSPFQAMNFSTFRFAMTQPVHPEWQSLGGSIQLRDASGQEVPATVLVKGNRITVDPCVTPEPSQCGSKQDILNTGETYTLQLTNLASLTDSSEENRFTGEFTFTPRDTGPTVVLQQTAVDSGNGELTSVLNGQALNAVTLNSVLQGEAGPSQQTGDLFAELAYAPAFDADEALPLRIPKGSVLKSTSLNVLVGGKVQVLDAATGEDQQTGTIKVTMLSDASGYMSPNQYTDDINAPRHITLFMDVSMNTEAAQPNAALSQDLMGVELRGIALVRDGVLTIDAIGMVEPNLLGQEFTDSTIAFHLQAATDADSVLDAENLRELDATPPSLVSWMPGPANAVPATRQSMQRPGDPIILFFDEPLDPASVENGVELIENGAPVTNLQARLDGTALVLNPQGGLKHGVPYSVSVDGLTDLAGNRAMVSPLSFELDSIEENGSPGNKGFPLALTTYPGYPCETDYENTLDLENGVFGKCWTADANNAGDVLPVSKMPADRPITVVFSKSLDLDSVIVGETFTVQEIAQEANGTVTVLNQQVAGRLEKNNQRIRFYPEQPWQVGAHYRYILASSEQSGTCTPGQYTSICDEDGIPLKTDLLEGLNDGDGNNGPDNLEIVFTGSEARSTVFTPLRNLPIRDTNSNLAIDCDDLGSESCLEPFNHQGSDSEGFLPSANAAKLLVTQDHAEDARVGCAVDGADCPRKKFIYQTYALNTEVIGPTVDPDTGRDAVKVLLYPTQLATTSLDVHLSLLSTVSSTGPQVLRMRYAKDDPECTGASCARNSLIPGYITENDQGETIFKTKAELFLDAPGLKATASILGIPTDLPLTHNLFGYPFTLELEGRVVFFDDGRMQIEQRNFNVPHIDVEAVALGIINTEIPLIIPEQGVYLNFISNPVKEIPAQYE
What is the function of this protein?
Required for growth on alkanes.  Probably involved in the uptake of micelle-solubilized alkanes.  May facilitate the transfer of alkanes from the outer membrane to the inner membrane.
What are the official names of this protein?
Alkane uptake protein B.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: TCPE_PONAB
Sequence: MASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPRMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAETSCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKIDDIRKPGESEE
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit epsilon, TCP-1-epsilon, CCT-epsilon.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: TAF1B_CHICK
Sequence: MDEEDAGDFNERCAQCSEVNWGLTDGGRFYCRTCHNVIERTREVVSTDVIPNARVQTISKGSRSQKKTDEGWEWYVCEGFQLVLKQQAEALEALGVCPQMKDEVLCNFWRRYLQKSQQAYCNRPAGETIKALSVCDSSTDMDSEPEQHSLLHFLSVSESDGDLQTDCSYASSAGKVSESTSVCSGSVDGSLYVRKNRKEKLRMSMPMTLSFCYMALLWLKEPMTLSDLLRFVVEGHIPYFNAYQHFPEKMKLYGLDLRIFCVESWPVYEEVYNKMVELAAFLDLPRFPDITDNCFLHPDVLCMKYLMEANLPDELHNWTCRLVKKTSIGEVDFLTLTPGNKSTRKVKYDVLAAAVIVVVLKLLFLLDDHYEWLLSDFSAEGNKNNKEGEGGPYFEFKKWYRVIKCTLDVEQKKLDEEKAKYLWKCEKPLFYSVKKKSKILRRRQMVENLQIQFGKLSGSVQPAGRPNPSSFLLSWSEESTDGSCFHGHSLKGILQEKHGLLTAINTDYWLCTDKLCNEKLCGHLAHYREEDFPKSYHFVLRLFSFLLRIQPSSIHEEVCVIEHKLFNKKLYKKPKRKRSLRK
What is the function of this protein?
Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription.  Binds rDNA promoters and plays a role in Pol I recruitment (By similarity).
What are the official names of this protein?
TATA box-binding protein-associated factor RNA polymerase I subunit B, RNA polymerase I-specific TBP-associated factor 63 kDa, TAFI63, TATA box-binding protein-associated factor 1B, TBP-associated factor 1B.
What is the protein family that this protein belongs to?
Belongs to the RRN7/TAF1B family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RXLRS_PHYIT
Sequence: MHFIYRVVLVLAAFALFKVDSISAGVTFNEEHLTIPRFTRPVEENLIKRQLRVMDDNERGFPSGPSLEKIEAMFQSLTNKITTKSKPSQRDVPDEKLSQLLGAAKPVNKAVEAAGRLKTLQTQKWLDEGKSTQEVFQLLELNKFMVPNFKKIEGTVFGLPDFNTWVNYVDDFNAKNPTKKESMIPTLRTIYSDEGLTRALELAKTYSTTNALATKLRKEQIQRWLDDAQTPKYVFEMFMIDDKVDGLLTNPRFIAWTKYVDDFNLQYPTSRASMEPPIAAHYGDDAVFAMLEAAKKVQLTENVASRLQAEQIKRLLNSNRSPEYVFEAFNLHETGDNLLSTPMFKTWFNYLESFNKKNTDKETLLAPIHRYYHDHGVAKIVAEGMKNPSTVELSKQLQIQRYKRWLHAERPPRDAFNTFILEKPGADVIIRYNERLDGKLYQVRLNKVSDGLLSSPEFQLWSKYLDDWNTKYPDQKQSMAKIFQALFTEDALAKMIMAARNNPSTQKIASLLENAFAKV
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves.
What are the official names of this protein?
RxLR effector protein PITG_15278.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm.
Protein: RPOA_XANCP
Sequence: MTVTANQVLRPRGPQIERLTDNRAKVVIEPLERGYGHTLGNALRRVLLSSIPGFAITEVEIDGVLHEYTTVEGLQEDVLDVLLNLKDVAIRMHSGDSATLSLSKQGPGTVTAADIRTDHNVEIINGDHVICHLTKDTALNMRLKIERGFGYQPAAARRRPDEETRTIGRLMLDASFSPVRRVAYAVEAARVEQRTDLDKLVIDIETNGTIDAEEAVRTAADILSDQLSVFGDFTHRDRGAAKPAASGVDPVLLRPIDDLELTVRSANCLKAESIYYIGDLIQKTEVELLKTPNLGKKSLTEIKEVLAQRGLALGMKLENWPPAGVAQHGMLG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: SYT_PYRCJ
Sequence: MRVLYIHAERFSWESREPALDIRDEPGSGAAANALVVFVSVERGDSSDEEFLRRVARDVVETAEKVKATAVVIYPYAHLSNDLARPYVAKEVVNKLYEVVKSEFKGEVYKAPFGYYKAFEVKCLGHPLAELSRSFKPEEARVAKAVEERRDVYLVLTPDGREHDPAAYSPADPDLKALIDKEVFKRELGGGEPRYLDYLRKFGFEWEPMSDVGHMRYGPEATVMMELVEDYAYQVAKSLGIPVFKIRGTNMFKLSEKAIETHARLFGERLYIVESDTDLILRYAACFQQFAMAKDWVISYRNLPFGMLEIADSYRHEQPGETVVLFRLRRFYMPDLHIFTKDLAEAVEVSYKVHEAIFREIGKLGRTYVSLYNVTEEFYKSHRDYLVELARREGKPILVRILPTQKYYWVLNVEYHIVDELGRPREIATFQIDVGNAQRFGIKYVDENNQVKYPVIIHTAIIGSVERYLYAVFDTIAKAEREGKTPRLPTWLAPVQVRIIPVARDNLKFAMEVADKLEEAGIRVDVDDRDETLSKRIRDAETSWVPYVCVVGSKEEETGTLSVRIRGEGQAKMTAEELIKRVREETRGYPTRPLYLPRLLSQRPTRG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCIN_CHICK
Sequence: MAPERHPPAFEGAGQESGLQVWRVERLELVPVPPSRHGDFFVGDAYLVLHTVRRGAAVAYRLHYWLGKECTQDESTAAAIFTVQLDDYLGGKPVQSREIQGYESNEFVSYFKGGIKYKAGGVASGFNHVVTNDLSAQRLLHIKGRRVVRATEVPLTWASFNKGDCFIIDLGNEIYQWCGSSCNKYERLKATQVAVGIRDNERNGRSRLITVEEGSEPDELITVLGEKPELPECSDDDDEMADIANRKSAKLYMVSDASGSMKLSVVAEENPFSMAMLLSEECFILDNGAARKIFVWKGKDANPQERKAAMKNAETFVQQMNYPANTQIQVLPEGGETPIFKQFFKDWKDKDQSDGFGKVYVTERVAKIEQIEFDATKLHESPQMAAQHNMIDDGSGKVQIWRVESSGRVPVEPETYGQFYGGDCYIILYTYPKGQIIYTWQGACATKDELTASAFLTVQLDRSLNDQAVQIRVSQGKEPPHLLSLFKNKPLIVYKNGTSKKEGQKPAPPTRLFQIRRNLMSVTRIAEVDVDAMSLNSNDAFVLKLPNNTGYTWVGKGVNKEEEQGAQYIASVLKCQTAKINEGQEPEEFWKALGGKKKYQTSSQLLTKAEDHPPRLFGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQVFVWIGKEANETERQESVKSAKRYIETDPSGRDKGTPIVIVKQGHEPPTFTGWFLAWDSNKWKN
What is the function of this protein?
Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane.  In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+).  Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity).  Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles (By similarity).  Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts (By similarity).  Regulates chondrocyte proliferation and differentiation (PubMed:17097081).  Inhibits cell proliferation and tumorigenesis.  Signaling is mediated by MAPK, p38 and JNK pathways (By similarity).
What are the official names of this protein?
Scinderin, Adseverin.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, podosome.
Protein: RS17E_SULTO
Sequence: MGNVYTKDIKRVAMQLYEKFKDQISTDYQANKKIVDAYVDVMSKKVRNRIAGYLTRYAKMQRTQVKNEVEEEYIEGEG
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: HFA1B_ARATH
Sequence: MESVPESVPSPNSNTPSIPPPVNSVPPFLSKTYDMVDDPLTNEVVSWSSGNNSFVVWSAPEFSKVLLPKYFKHNNFSSFVRQLNTYGFRKVDPDRWEFANEGFLRGRKQLLKSIVRRKPSHVQQNQQQTQVQSSSVGACVEVGKFGIEEEVERLKRDKNVLMQELVRLRQQQQATENQLQNVGQKVQVMEQRQQQMMSFLAKAVQSPGFLNQLVQQNNNDGNRQIPGSNKKRRLPVDEQENRGDNVANGLNRQIVRYQPSINEAAQNMLRQFLNTSTSPRYESVSNNPDSFLLGDVPSSTSVDNGNPSSRVSGVTLAEFSPNTVQSATNQVPEASLAHHPQAGLVQPNIGQSPAQGAAPADSWSPEFDLVGCETDSGECFDPIMAVLDESEGDAISPEGEGKMNELLEGVPKLPGIQDPFWEQFFSVELPAIADTDDILSGSVENNDLVLEQEPNEWTRNEQQMKYLTEQMGLLSSEAQRK
What is the function of this protein?
Transcriptional activator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor A-1b, AtHsfA1b, AtHsf-18, Heat shock factor protein 3, HSF 3, Heat shock transcription factor 3, HSTF 3.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ADD_SHEDO
Sequence: MIDKSIPLVDLHRHLDGNVRVQTIWELGHQHGIALPAQSLAELAPFVQIQGKENSLVAFLKKLDWMVAVLADLDAVKRVAYENVADAALSGLDYAELRFSPYYMAMNHNLPIEGVVEAVIDGVNAGLKDHAVKINLIGIMSRSFGQEKCLLELEGLLAHKDKLVAMDLAGDELGFPGDLFNDHFKRVRDAGLAITAHAGEAAGSESMWQAIQTLGATRIGHGVNAIHDPKLMEYLVKHKIGIESCPTSNLHTSTVDNYDVHPLRTFLDAGVLIGLNTDDPGVSNIDIAHEYRVVKSEMGFSDAQLAQLQRNGVEMAFMSDSDRKALYAAKA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: HPR_GEOKA
Sequence: MKATEQHYSIKEAMLFSQRIAQLSKALWKSIEKDWQRWIKPFDLNINEHHILWIAYHFKGASISEIAKFGVMHVSTAFNFSKKLEEKGLLSFSKKQDDKRNTYIELTEKGEEVLMKLMETYDPTKNAVFNGALPLRELYGKFPEILEMMCIVRNIYGDDFMEIFERAFENIKEDFIEQDGKLVKRKPKTEEHEKELASQAN
What is the function of this protein?
Negative regulator of protease production and sporulation.
What are the official names of this protein?
HTH-type transcriptional regulator Hpr, Protease production regulatory protein Hpr.
Protein: ECFT_LIMFC
Sequence: MNSRVLFGSFVPVDSVLHRLDPRLKLVTCFWYVVIIFFAKGPLTYLLLVAMLGAMIGLSKVPLKMYWAGLKPLLWVIGLTIAIQVLFSSGGHVYWHWGLMAITSGGINQALVILARFILIVLASTVLTATTPPLRLADAIESLMKPLKKIKVPVNQIAMMISIALRFIPTIMDEVNTIVKAQQARGVDFTSGSVYTRVKRMVPIMVPLFVGAFRRAEDLAVAMEARGYDPDQERTRYRQLTWRRPDSIALAVVVIVSVLFFVARILL
What is the function of this protein?
Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NCAP_WBV24
Sequence: MSGMYPQPLMMMPQQQRRPRKPRTKSAPKPPTTSKMSEKTKKEVTKSTMSTEKQIPMPTIPAASKGSLKDLDVRNNLNQQELNGIYYDTVNNLNACHGRMIFQPTGGSLTEGTLTVTIKLRVKSDQCLKMCSAFHKRNTNLETPLSAVDISKESEKSLGKD
What is the function of this protein?
Major structural component of virions that associates with genomic RNA.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NC, Protein N.
What is the protein family that this protein belongs to?
Belongs to the torovirinae nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Note=Located inside the virion, complexed with the viral RNA.
Protein: PSD_CAMJE
Sequence: MSFSKESSRLFGFVAGIKFPKMIQKVINENYVKYFNINMSEFKAPCEYESLNALFTRTLQIPRKFEEGFISPSDGKILECGSTFLANEEHFAFSIKGHAYSVEELLKDSFEKDELKNGLDYVNIYLSPKDYHRYHSPCDMQILSATYTSGVLYSVNEKHLERISNLYVKNERVSLKCQNEKGIFWLVFVGAQNVGKMRFNFDASIQTNAKISHNFTRKYENLNFKKGEELGNFELGSTIVLISQKGLLTFNLKVGQGIKFGEKIAD
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HS22C_PETHY
Sequence: MACKTLTCSASPLVSNGVVSATSRTNNKKTTTAPFSVCFPYSKCSVRKPASRLVAQATGDNKDTSVDVHVSNNNQGGNNQGSAVERRPRRMALDVSPFGLLDPMSPMRTMRQMMDTMDRLFEDTMTFPGSRNRGTGEIRAPWDIKDDENEIKMRFDMPGLSKEEVKVSVEDDVLVIKGEHKKEESGKDDSWGRNYSSYDTRLSLPDNVDKDKVKAELKNGVLLISIPKTKVEKKVTDVEIK
What are the official names of this protein?
Small heat shock protein, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PANB_BORBR
Sequence: MSVPTAAKRITTRQLRMRTPDEPIVALTAYTAPIAGLLDAHCDLLLVGDSLGMVIYGMETTLPVTVDMMIQHGRAVMRGSQRACVAVDMPFGSYQEDERQAYRNAARIMAETGASCVKLEGGAEMASTVAFLVERGIPVMGHVGLKPQSVHGHGGFRTVGRGAEAEQVMADAQAIAAAGAFTVVIEGTLEPVARAITEALPVPTIGIGASPACGGQILVSDDVLGLFSDFTPRFVKRYAQLGPIIEQAAAAYASEVRARTFPAPEHCTGMPAPDGRPA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2058_BRADU
Sequence: MYNRVDGEYAHTEQAEESSWPADGSECAQTLTEIARLESLAPGELFDRMGLCFSKPHTSDAIDDSSNTSGLSTSSLSSSSELSVATSPVRPLFDYRTAELPQANVSGICVGLAAEWLLDLPSSASSRMGVLLPGTENHRSAARRQEQSEKLKTQLKEDKAEGSHNFQAKSTILRDAGLEPSAEETRYRFGTSSCIDKIVNELAQDPSVHLVSLKFVQPGAGTHTIATATSNGTTILSDPNYGEFTVPSDRVGGLFKSLAERYSTLNKRDISAVVTQRIRYGHPNATDLALFPRAEPHR
What is the function of this protein?
Potential cysteine protease, which may play a central role after invasion of host cell.
What are the official names of this protein?
Putative cysteine protease YopT-like blr2058.
What is the protein family that this protein belongs to?
Belongs to the peptidase C58 family.
Protein: ASF1B_HUMAN
Sequence: MAKVSVLNVAVLENPSPFHSPFRFEISFECSEALADDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQLQRNILASNPRVTRFHINWDNNMDRLEAIETQDPSLGCGLPLNCTPIKGLGLPGCIPGLLPENSMDCI
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (PubMed:11897662, PubMed:14718166, PubMed:15664198, PubMed:16151251, PubMed:21454524, PubMed:26527279).  Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly (PubMed:11897662, PubMed:14718166, PubMed:15664198, PubMed:16151251).  Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol (PubMed:20953179, PubMed:21454524, PubMed:26527279).  Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA (PubMed:11897662, PubMed:14718166, PubMed:15664198, PubMed:16151251).  Required for gonad development (PubMed:12842904).
What are the official names of this protein?
Histone chaperone ASF1B, Anti-silencing function protein 1 homolog B, hAsf1, hAsf1b, CCG1-interacting factor A-II, CIA-II, hCIA-II.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: GHC2_HUMAN
Sequence: MTHQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRNLKMEMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGAGCRALVIAPLFGIAQGVYFIGIGERILKCFD
What is the function of this protein?
Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system).
What are the official names of this protein?
Mitochondrial glutamate carrier 2, GC-2, Glutamate/H(+) symporter 2, Solute carrier family 25 member 18.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KCY_LEPBJ
Sequence: MNENVIALDGPAGSGKSTVARQIAERIGFNYLDTGAFYRALTLYLFRLHGNSPNTESFADWVKTSEAERSLSDIRILCEFSAGKENRIFLNGEEVSLAIRTPEITREIKHIANRRIYRNFVNQELHSLAKLHKLIIDGRDIGTEVFPDAKFKFYLTASSKVRAERRFLQLQEQGIEADRDEIEKEIILRDKSDMEREIAPLYQANDAILIDTDILSKNSVISKILKILDR
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_SACD2
Sequence: MTTQELNVDSAEIAKFERLAARWWDLEGEFKPLHDLNPLRANYIDERAQVAEKKLLDVGCGGGILCEAMAQRGAIVTGIDMGDAPLEVAKLHSLESGVNVDYIKTTAEEFAAKHPQSYDVVTCLEMLEHVPDPAQTIAACAQLVKPGGDIFFSTINRNPKAYLFAVVGAEYVLKMLPKGTHDYNKFIRPSELAQWMRNAGLELQEMCGMTYNPITKHYKLNAKDVSVNYIMHARKI
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SEPF_SYNSC
Sequence: MSLISRLRAVVAGDDYLDGELDDFAYDDEQDDQDQRALQADGGALATIGDSNPFDLGGDLPGSNVIGMPGISNAAAEVNVMEPRSFDEMPRAIQALRERKTVILNLTMMEPDQAQRAVDFVAGGTFAIDGHQERVGESIFLFAPSCVTVTNTGHDEASAPTVVSREADAADVDEYASAPSPAWGAAAL
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: AMPA_METC4
Sequence: MAGGIEITFEPLSSRGTGGDLVVFVGDDLALSGAASEALGQPGTELVARAAASERFKGKAQSALVLPAPAGVEADRLVVIGLGSEKDRAKIDWTVLGGFTAGKVGARSARVVIDGPGFAASARDVADFTLGARLRSYRFDQYKTKKKDEDEAGAALTLRVADPSGAQAAARSAEAVAEGVILARNLVNEPPNVLYPEEYARRVSELTQLGVEVEILDVARMKEIGMGALLAVAQGSAREPRVVIMRWNGADDAAEPPLALIGKGVVFDSGGVSIKSAGGMEDMKGDMGGSAAVVGTLHALASRKAKANVIGAIGIVENMPDGAAYRPSDIVTSLSGQTIEVINTDAEGRLVLADVLWHIQATYKPKAMIDLATLTGAIIVALGQDIAGLFSNDDALSGQITAAGEAAGEKVWRMPLIPAFDKAIDSKFADMKNTGGRHGGAATAAAFLKRYVNDVPWAHLDIAGVGMSSTPSEINRSWGAGWGVRLLDRLVREHYER
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.