PharMolix/UniProtQA huggingface dataset:
Protein: UVRC_CAUVC
Sequence: MTDTPSASDAEAPLRQAAPLWGAALIKDEVTRLPDAPGVYRMIGEADEVLYVGKAKSLKKRVVQYAQGRFHTNRIANMVDATRAMEFITTRTEADALLLEINLIKQLKPRFNVLLRDDKSFPEIVIRRDHDAPQLRKHRGAHTIKGDYFGPFASAWAVNRTLNTLQKAFLLRSCSDSVYDSRDRPCMLYQIKRCAAPCTGLIGKDDYQALVDQAEAFLRGKSRAVMATMAKAMEEAAEELEFERAARLRDRIRALSAVAQETQINPETVEEADVVALHVEGGQACVQVFFFRAGQNWGNRAYFPRITGAADDPEDETVTEEQRIITAFLGQFYDDKPIPRLILANVQPAESELLSEAFALKSGRKVEIAVPKRGEKADLVQHVLTNAREALGRKMAEGSAQTKLLAGVAEAFKLDAPPERIEVYDNSHIQGANAVGGMIVAGPEGFMKGQYRKFNIKSTELTPGDDYGMMKEVLRRRFARLVKEEEEGDDANRPDLVLVDGGQGQLDAAIEIMADLGVDDIAVVGVAKGPDRDAGLERFFIPGQTPFMLEPKSPVLYYLQRLRDEAHRFAIGAHRTRRSMDLKKNPLDEIEGVGPGRKKALLHAFGSAKGVGRASVEDLVKVDGVSQALAERIFGFFRKG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBCR_EMENI
Sequence: MYPWSSTGTSPFSHPDNEGAESGDMSMGEEQQQPHQRRQKFNNLRACQSCRASKVRCDQPNPGMPCLRCQKSGKPCVDAASQPGKRQRQPINSILEMESRIETILSSAELQDSAGDGETAHSTALRSPSQLSHHIQPFQHLPMGFAIPFNGGNSGTEDLNSSIRSWLNDNITDLDARTTETIFSHYLTNMVPTFPVVVFATGTTAADVRRNNPILFLAILDVASSGFCALETQRKLRKLIVQAYVHCMLRTEQYTLGLLQALIVSATWYRTIEPVEPGEQMDIYQISHTAANMALIMRLGESLNAKSWGGPMFPRREMKKGPGSAFQADSLEARRVWLGCHYICSNTSMSLRAPNIMRWTRLMDECLEVLENSPAALLSDRLLCQHIRLQHITEEFAMHLSAEEASAPAKSRAIQIQVTHRAFKRQLSEWRRTVGDGWDAHCTATSDDVPEDNAQRLTPPPPIVAIEPHAITEFMDTIDNIFRVFTSLDMSTIRALPAMYLIRIIYTFIILVKLYFAAAKLPAQDAVLQVDGLQVSRRFNRVIQMTAGWGPLWPATKLTTVFTKMRSWFESGGDNNCQRLQQAAAWLTGWELKPPSQGRDAHAMNMAEVVSDDGSIVASSSRGPASWVPSLASTDVDTLAFSHEPPLGTEFSIAPPPFRSMSCATKSCSPQAGAAEFMHDEEVPLEGQRLGDLPNIDQMDDVGMDWSQYTNMGFDLYNLDAPFLPNPPSGFDPDAAMKDNCADRNT
What is the function of this protein?
Transcription factor; part of the gene cluster that mediates the biosynthesis of the diterpene ent-pimara-8(14),15-diene (PD) (PubMed:22506079, PubMed:27098256).  Acts as a positive regulator for the cluster gene (PubMed:22506079).  Down-regulates the expression of the penicillin gene cluster, two putative polyketide clusters, and one putative nonribosomal peptide cluster (PubMed:22506079).
What are the official names of this protein?
Transcription factor pbcR, Pimaradiene biosynthesis cluster protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: FIEF_SALG2
Sequence: MNQTYGRLVSRAAIAATAMASALLLIKIFAWWYTGSVSILAALVDSLVDIAASLTNLLVVRYSLQPADDEHTFGHGKAESLAALAQSMFISGSALFLFLTSIQNLIKPTPMNDPGVGIGVTVIALICTIILVTFQRWVVRKTQSQAVRADMLHYQSDVMMNGAILIALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDAERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHFVADQVEQAILQRFPGSDVIIHQDPCSVVPREGRKFELV
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCJ12_BOVIN
Sequence: MTASGRTNPYSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEAHGRTPCVLQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYKIDYSHFHKTYEVPSTPRCSAKDLVENKFLLPSTNSFCYENELAFLSRDEEDEVDGEQDSLGPQARRDFDRPQAGTALEQRPYRRESEI
What is the function of this protein?
Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells.  Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium (By similarity).
What are the official names of this protein?
ATP-sensitive inward rectifier potassium channel 12, Potassium channel, inwardly rectifying subfamily J member 12.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: VF355_IIV6
Sequence: MKNIFLDLDNTLICAEPFEDITDLGRFKERASHFDFKNMEDYYLICGRPYLQPFLDYLFKNFNVHIWTAASKGYASFIIEEFILKKDPSRKINLVLFDHHCRVSKRVYKKEKASKKLEMLWTIWKLQEFDKENTFIIDDLEEVKESQVKNCFSVKPFFFMENDSEYDQELMRLKDVLNRHLN
What is the function of this protein?
May function as a phosphatase.
What are the official names of this protein?
Putative CTD phosphatase-like protein 355R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 355R family.
Protein: GCST_THENN
Sequence: MKRTPLYERHVALGAKMVDFAGWIMPLYYSSIFEEVMAVRKSVGVFDVSHMGEIVVEGQETVDFVNFLVTNDFSAIPEGKAMYTVMCNETGGIVDDLVVYRISHEKAIMVVNAANIEKDYEWIKVHAKNFNVEVRNVSDETALVAFQGPKSQETLQRVVDIDLEGIGYYSFQWGRLDGERVLVSRTGYTGEDGFELMMNAESAAKIWDTLVEIAGNVDGKPAGLGARDVCRLEASYLLYGQDMDESTNPFEVGLSWVVKMNKDFVGKEALLKLKEKVERKLVALELSGRRIARKGYTVLKEGKEVGKITSGNFSPTLGKSIALALVSRCVKTGDRLEVVFPGKNVEAHVVKKPFYRGSVRREA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: NUDI_KLEP7
Sequence: MRHRTIVCPLIENKGHYLLCKMAADRGVFPGQWALSGGVEPGERIEEALRREIREELGEKLILTHIAPWCFRDDTRVKTYPDGHQETIYMIYLIFNCVSANRDVTINEEFDDYAWVKAEDLKNYDLNAATRVTLSLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: RF1ML_RAT
Sequence: MRSGFLRSARRLWARRAISRMPPPSEELLARGGPLRAFLERRVGSEAGGLDAGSPQLAAAARLLNEKERELRDTESLLHDENEDLKKLAESEIALCQKEIAELKHRIISLLVPSEDMDGSDLILEVTAGVGGQEAMLFTSEMFDMYQQYAAFKRWHFETLEYFPSELGGLRHASASIGGPEAYRHMKFEGGVHRVQRVPKTERQGRIHTSTMTVAILPQPTEIKLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPTGIISECQQERSQLKNRELAMKKLRARLYSMRLEEETAKRYSARKIQVGTKGRSEKIRTYNFPQNRVTDHRINKSLHDLESFMQGDCLLDDLIQSLKDYSDYESLVEMISRKD
What is the function of this protein?
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
What are the official names of this protein?
Peptide chain release factor 1-like, mitochondrial, Mitochondrial translational release factor 1-like.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RBFA_CLOB8
Sequence: MANYRGGRINEEFKREISNLIQNEVKDPRLTAMISVTDVKVTKDLRYAKVYVSIFSKDDEEKKNNLEALKNASGFIRKSVGQKINLRHTPEIIIELDDSINYGMHMDELIQRISKGNE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_EUGST
Sequence: YRLTYYTPDYQVAETDILAAFRMTPQPGVPAEECGAAVAAESSTGTWTTVWTDGLTQLDRYKGRCYDLEPVPGESNRYIAYIAYPIDLFEEGSVTNLLTSIVGNVFGFKALRALRLEDLRIPPDYAKTFWGPPHGIQAERDRLNKYGRPLLGCTVKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQSVMRWRDRSXFCAEAIYKAQAETGEVKGHYLNATAGTVEEMFKRAVFSAQLGVPIIMHDYITGGFTANTSLSMYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKTLRMSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDPYVEKDRSRGIYFTQDWCGMGGTMPVASGGIHVWHMPALTEIFGDDACLQFGGGTLGHPWGNRPGAAANRVASEACVQARNEGRDLSREGGDVIREACKWSPEL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVC_ANASK
Sequence: MIVLGIDPGSRRCGYGVVAREGARLTVVESGVLVPGDLPMAQRLGRILEGLDALIARARPVEASVESVFSGASPRSALVLGQARGVALAAAARAGLPVFEYAPSEVKLAFTGNGRAGKDQMLRTARMLLGAAPDLSDEADALAIAVCHLARRAFAVPAAGAGRAAAARAAAARLRPSRRDHRGTP
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TRUB_STRR6
Sequence: MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVLPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSSLDEKLVDEAIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVIIYQFERTSPISYDGQLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAEKVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKRGNLYKPRKVFS
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CSEN_HUMAN
Sequence: MQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI
What is the function of this protein?
May play a role in the regulation of PSEN2 proteolytic processing and apoptosis.  Together with PSEN2 involved in modulation of amyloid-beta formation.
What are the official names of this protein?
Calsenilin, A-type potassium channel modulatory protein 3, DRE-antagonist modulator, DREAM, Kv channel-interacting protein 3, KChIP3.
What is the protein family that this protein belongs to?
Belongs to the recoverin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Endoplasmic reticulum. Golgi apparatus. Nucleus. Note=Also membrane-bound, associated with the plasma membrane (PubMed:15485870). In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus.
Protein: RS16_RICB8
Sequence: MAVKIRLARGGAKKRPFYRVVVANATAPRDGDFLEKVGTYNPMLAKDSNERVVLKADRVEYWLKSGAKPTDRVARFIEQAGIALPEKVKKEMEVKLKNRKAKPSKKEAKEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y3427_GLOC7
Sequence: MDIQLINIGFGNIVSANRVIAIVSPESAPIKRIISDARERGQLIDATYGRRTRAVIITDSSHVVLSAIQPETVAHRFVVNKEVQANSN
What are the official names of this protein?
Putative regulatory protein PCC7424_3427.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: TRPC1_BOVIN
Sequence: MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKEILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQSADALLVAIDSEVVGAVDILLNHRPKRSSRPTIVKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILGAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSNDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYHEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKEEAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFYVYTSSILGPLQISMGRMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTPKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAILCTRFSYGEELQSFVGAFIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRHLNEKRDENYQKVMCCLVRRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN
What is the function of this protein?
Thought to form a receptor-activated non-selective calcium permeant cation channel.  Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.  Seems to be also activated by intracellular calcium store depletion.
What are the official names of this protein?
Short transient receptor potential channel 1, TrpC1, Transient receptor protein 1, TRP-1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BETB_STRMK
Sequence: MTTLPVQQLYIHGQRVDATSGKTFKTVNPATGEVIAEVQVASQADVERAVQSASEGQKVWAAMTAMERSRILRRAVEILRERNDELAHLETLDTGKALAETTTVDIVTGADVVEYYAGLATAIEGIQLPLRESSFFYTRREPLGVVAGIGAWNYPIQIAMWKSAPALAAGNAMVFKPSEVTPLTAIRLAEIYTEAGVPAGVFNVVQGPGREIGQWLTEHPVIEKISFTGGVATGKKVMASAASSSLKEVTMELGGKSPLVICDDADLDRAADIAVMANFFSSGQVCTNGTRVFVPRSMLAAFEAAVVERVKRIRIGDPMAAETNFGPLTSFPHMENVLRYIESGKAEGARLLTGGGRATEGALANGAYVLPTVFSDCRDDMTIVKEEIFGPVMSILAYDDEDEVVRRANDTTFGLAAGVVSKDISRAHRIIHRLEAGICWINTWGESPAEMPVGGYKESGVGRENGISTLGHYTRIKSVQVELGDYASVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: GLMM_YERPY
Sequence: MSNRKYFGTDGIRGKVGESPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKPLTCVESAELGKANRIVDAAGRYIEFCKGTFPSELSLNELKIVVDCANGATYHIAPSVLRELGATVITIGCEPDGMNINEECGATDVRLLQERVLAEGAHVGLAFDGDGDRLMMVDHLGNKVDGDQILYIIAREGLRQGQLKGGAVGTLMSNMGLQLALKDLGIPFVRAKVGDRYVLEAMQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLTAMVRNHMSLHDLCSGMKLLPQILVNVRFSGEHNPLKSDEVEEVTRQVEKELGGRGRVLLRKSGTEPLIRVMVEGDAEESLIAEMANRIADAVKAAG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MNMC_PSEE4
Sequence: MSTLLQHAQIDWDDQGRPHSRQYDDVYFAINEGIDETLHVFIEQNQLRQRFAELKPHDCLVIGETGFGTGMNFFCAWQLFAELAPAGARLHFVSVEKYPLSRDDLARAMQLWPELAAFTQPLLEQYVAIHPGFQQFSLDGGQVTLNLMIGDALEQLPQLDARIDAWFLDGFAPAKNPDMWTPELFTQLARLSRPGTTLGTFTTTGWVRRSLIEAGFTMKKVPGIGKKWEVMHGVYTGAAAAPAAPWYARPTDLPGPREALVIGAGLAGSATARSLAERGWQVSVLERHAGPAQEASGNPQGVLYLKLSAHGTTLSQMILSGFGYTRRWLEHLQRGQDWDACGVLQLAFDDQEAARQAKLAAAFDESLLQRLEHDQAEAVAGIALASGGLFYPEGGWVHPPALCQAQLGHPNVRLLNHHEVIELRKVDGQWQAWDGERLLASAPLVVLAGAADVRRFPACAELPLKRIRGQITRLPATEASRALRTVVCADGYVAPPRGDEHTLGASFDFHNDDLTPTTAEHQGNLGLLEDISTDLATRLGCAELDAEQLEGRAAFRCTSPDYLPIVGPVADVQAFNTTYAMLAKDARQVPDIACPWLDGLYVNSGHGSRGLITAPLSGELIAAWACGEPLPVPRAVAEACHPNRFALRRLIRGK
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDH_CITK8
Sequence: MKKTGYFLLAVVIVAAVAGIGYWKLAANPNALRDIVLQQCVPNQLQQQNPAPCAEVKPDAGYVVFKDRNGPLQYLLMPTYRINGTESPLLVEPYTPNFFWLAWQARSFMSQKYGKDIPDSAISLAINSRSGRTQNHFHIHISCLRPDVRAQLDDNLAKVSTRWLPLPGGLRGNEYLARRVTESELAQRSPFMMLAEEVPDAREHMGSYALAVVRQSDDSFVLLATQRNLLAFNLASAEEIQDHQCEILQ
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ISPH_ACIB3
Sequence: MEIVLANPRGFCAGVDRAIAIVNRALECFNPPIYVRHEVVHNKFVVDDLRQRGAVFVDELDQVPDDSIVIFSAHGVSKAVQQEAERRGLKVFDATCPLVTKVHIEVTKYAREGTEAILIGHEGHPEVEGTMGQYDKLKGGDIYLVEDEADVAALEVRHPEKLAFVTQTTLSIDDTAKVIDALRAKFPNIQGPRKDDICYATQNRQDAVRDLAEKCDVVLVVGSPNSSNSNRLRELAERMGKAAYLVDNADQLEQSWFNDTCKIGVTAGASAPEILIKQVIQRLQDWGAQAPKELEGREENITFSLPKELRIHVTQA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: W_HENDH
Sequence: MDKLDLVNDGLDIIDFIQKNQKEIQKTYGRSSIQQPSTKDRTRAWEDFLQSTSGEHEQAEGGMPKNDGGTEGRNVEDLSSVTSSDGTIGQRVSNTRAWAEDPDDIQLDPMVTDVVYHDHGGECTGHGPSSSPERGWSYHMSGTHDGNVRAVPDTKVLPNAPKTTVPEEVREIDLIGLEDKFASAGLNPAAVPFVPKNQSTPTEEPPVIPEYYYGSGRRGDLSKSPPRGNVNLDSIKIYTSDDEDENQLEYEDEFAKSSSEVVIDTTPEDNDSINQEEVVGDPSDQGLEHPFPLGKFPEKEETPDVRRKDSLMQDSCKRGGVPKRLPMLSEEFECSGSDDPIIQELEREGSHPGGSLRLREPPQSSGNSRNQPDRQLKTGDAASPGGVQRPGTPMPKSRIMPIKKGAQTRSLNMLGRKTCLGRRVVQPGMFADYPPTKKARVLLRRMSN
What are the official names of this protein?
Protein W.
Protein: ACTC_TAKRU
Sequence: MCDDDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETAYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, alpha cardiac muscle, Alpha-cardiac actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HMEN_TRIGR
Sequence: NSGYSNIHNEMLFDFVVFVFTGPRTRKVKRREKKADEKRPRTAFSASQLQRLKQEFQQSNYLTEQRRRSLAKELTLSESQIKIWFQNKRAKIKKASGLKNDLARQLMAQGLYNHSTVPLEADSMDTKLLNGQNTSGDCSRSDYTSDSDGDSLTH
What are the official names of this protein?
Homeobox protein engrailed, SU-HB-En.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYNS_THAPS
Sequence: MLSQCLSRTSRAVAGSNGHRFSKLSAIDGVHHAHPSPRRYTTFSSSDHADRTKRLLDAKEKAGLTYDKLASKLGITNTYAAQILLGQTKLSAATAAKLQAALPISEQDIEDMKSTYPMRGFDDEILKEPNVYRTYEAITHYGEAIKSIINEQCGDGIMSAIDFYCDVGTTTGVNGEKRVVITFNGKFLPHIEQKEEDNTAKSPRD
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: PSTB1_CALS4
Sequence: MEIELKNVNYFRDGKYILKNVYFKFEKNGIYTVVGPSGAGKSTMLKLINRLIEPTEGAIFINGVEYKNIDVILLRRKIGMVFQRPFLFEGTVKENIELGPSLRGEKNIDALFYLEAVGLSKDYLFKDVNNLSGGEAQRVSIARALANSPEVLLLDEPTSSLDPTSTSIIEELIKRLNREGIMVILVTHNMEQAKRIGDYTLFLYKGELIEARKTWEFFENPVSEVSKLFLEGKLKEMIK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RSSA_TRIGR
Sequence: MSGGLDCLALKEDDVQKFLASGAHIGSSNLDYQMTQYVYKRKPDGTYIINLRRTWEKLLMAARIIVAIENPADVCVISSRPYGQRAVLKFGAHTGATPIAGRYTPGTFTNQIQAAFREPRILIVTDPRSDHQPVTEASYVNIPVIALCNTDSPLRYVDIAIPCNNKSIHSIGLMWWMLSREVLRLRGAISRDVTWEIMCDLYFFRDPEEAEKEEQEARDRATAVKEEPAQPYAEQWSDPVAVPPAGQPVAEVTDWAADSVKAPVAGIGTYGGPSEDWAVADAPAAPAAPTPAAPSQEFTATDDWGGAASNDWAISS
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_IDILO
Sequence: MALTVFNTLTRKKQLFEPIQPGHVGIYVCGVTTYDYCHIGHARTYVAFDIVVRYLRKLGYSVKYVRNITDLDDKIIKRAAENGEDFHQVTERFIREMHKDFDALNLVRPDIEPRVTSHMDEIILMIERLIENGNAYEAGNGDVLFDVSTFNDYGKLSRQDLEQLQAGSRVDVDAAKQDPLDFVLWKSAKPGEPSWSSPWGEGRPGWHIECSAMNKKHLGSTFDIHGGGSDLSFPHHENEIAQSCCANQSEYVKYWMHSGMVQVDNEKMSKSLGNFFTIRSVLEQYDAETVRYFLLSSHYRSQLNYTQENLDQAHSALERLYTALRDITPQTASEELRSKYWQSFQQAMDDDLNAPEAMSVLFEIAREINRNRESAPDTAAQLAHVLLELAEVMGLLQQSPEEFLQGDDDDVAKIEALIAKRNQAREDKDWAAADEARDELTNMGIVLEDGAEGTRWRRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.