PharMolix/UniProtQA huggingface dataset:
Protein: PDXJ_HELPJ
Sequence: MRFGLNIDHIVTLREVRKTYEPEILEALFIAKNTHKVDLITIHLREDKRHIQNEDVLRLLEISPLPINIECSINAEITDFLCSLKNKPSKVTIVPENRNEVTTEGGLDCSLKGLEEVIRAYHNKGIEVSLFVDPLKDALHFAKEHQVKQVEFHTGVYANLHNALYSNANNQIHAISTLKDKCPKELKEELHNAFLQLRRMSKEAFFMGIVVCAGHGLNYSNVKELLKIPSLRELNIGHSVVSKAVLVGLEKAILEMAQLIKR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODF3A_MOUSE
Sequence: MAEEVWMGTWRPHRPRGPIMALYSSPGPKYLIPPTTGFVKHTPTKLRAPAYSFRGAPMLLAENCSPGPRYSVNPKILKTGKDLGPAYSILGRYHTKTLLTPGPGDYFPEKSTKYVFDSAPSHSISARTKTFRVDSTPGPAAYMLPVVMGPHTVGKVSQPSFSIKGRSKLGSFSDDLHKTPGPAAYRQTEVQVTKFKAPQYTMAARVEPPGDKTLKPGPGAHSPEKVTLNKPCAPTVTFGIKHSDYMTPLVVDVE
What is the function of this protein?
Outer dense fibers are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail.  May help to maintain the passive elastic structures and elastic recoil of the sperm tail.
What are the official names of this protein?
Outer dense fiber protein 3, Outer dense fiber of sperm tails protein 3, Sperm tail protein SHIPPO 1.
What is the protein family that this protein belongs to?
Belongs to the ODF3 family.
Protein: NODJ_RHIS3
Sequence: MGKGFSAALPANAWNWIAVWRRNYLAWTKVALASILGNLADPMIYLFGLGTGLGMMVGRVEDASYPAFLAAGMVATSAMTASTFETIYATFPRMNEQRTWEAILHTQLTLGDIVLGELVWATTRAFLAGTAIAMVAVIAGYSAWSSVLYVLPVIALTGLAFASLAMIVTALAPSYHYFIFYQTLFLTPMLFLSGAVFPVTQLPSTFQHIAGILPLAHSIDLIRPGMLDRPAGDIALHIGALCIYAVVPFFLSMVLLRRRLLR
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit encodes the transporter (By similarity).
What are the official names of this protein?
Nodulation protein J.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_STREM
Sequence: MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYACDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIGDYDCKVLMHFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPRK_HUMAN
Sequence: MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
What is the function of this protein?
G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins.  Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A.  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.  Signaling leads to the inhibition of adenylate cyclase activity.  Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.  Plays a role in the perception of pain.  Plays a role in mediating reduced physical activity upon treatment with synthetic opioids.  Plays a role in the regulation of salivation in response to synthetic opioids.  May play a role in arousal and regulation of autonomic and neuroendocrine functions.
What are the official names of this protein?
Kappa-type opioid receptor, K-OR-1, KOR-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KADA_THEKO
Sequence: MPFVVVITGIPGVGKSTITKLALKKTRAKFRLVNFGDLMFEEAVNMGLVKHRDEMRKLDPLTQKELQLKVAQRIVEIARKEPVLLDTHATIRTPAGYLLGFPREVIEILNPNFIVIIEAAPSEILGRRLRDLKRDRDVETEEQIARHQDLNRAAAIAYAMHSNALIKIIENHEDKGLEEAVNELVKVLDLAVSEYA
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_YERPP
Sequence: MDQKFAVFGNPISHSKSPRIHTLFSEQTGIEHRYGKVLAPSEAFENTLVSFFADGAQGANITTPFKERAYDQCDELTDRASLAGAVNTIKRLEDGRLLGDNTDGIGLLSDLERQNLIRTTDHILLVGAGGAARGVILPLLSYGCTVVVTNRTHTRAQQLAKVFNHIGDIDVCEMSELAGQRFDLVINATASGLHGEVPNLPAAILTSQTRCYDMFYQAGTTPFLAWAQRLGLADYADGLGMLVGQAAHAFKLWHGVMPEITPVLAQLRSELGK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YKO8_CAEEL
Sequence: MSTQIPMDPPKFLCMPARPLVVGLAVFGAIRSFVQFWMSSGFGMAGTHFCVLLLDLLLLFGAYKNDVFALKWSQRVTFACVLIAIIRFMIYPVVFASYMASGLSRNFTGIDSEEIEILGNVTTPEQNFVFGMISGFTLEFATALSIGVESLKYLLVHRLWEYAKATEASSSSRYVIP
What are the official names of this protein?
Uncharacterized protein C05B5.8.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YCNE_BACSU
Sequence: MIVLQAYIKVKPEKREEFLSEAQSLVQHSRAEEGNAQYDLFEKVGEENTFVMLEKWKDEAAMKFHNETAHFQGFVAKGKELLSAPLDVVRTELSE
What is the function of this protein?
Putative monooxygenase that may contribute to the degradation of aromatic compounds.
What are the official names of this protein?
Putative monooxygenase YcnE.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
Protein: YIDC_RUEPO
Sequence: MDDQNKNLILATALSFLVILVWFILFPPPEQTEAPATEIATTNGTAVQTPTAAATEGGAGEVPALDSAAPTQAEAPRVQIDTPRLKGSVSLLGGRIDELSLKDYRVSLDEDAEIVEMLTPAGSTSAYYALYGWAPGAGLNAADVPGPLTEWSLESGDTLSVGTPVTLSWSNGSGVTFRRTLAVDEDYMFTVTQSVENGSAAPIGAAPYGILARHGIGEDADLPGLKNFFILHEGVVAMNDGTLSEIDYKDVRKFDIDPNEGAQAEVFQNKSDGWIGFTDHYWMATLIPGSGTAFKSAAKYDARRKIYQAETVLPTMSVAPGESAEVTTRLFAGAKEWESIRAYQQDGVQKFLDSIDWGWFFFLTKPIFWLLHQINGLIGNMGWSIIGLTLIIKAIVFPLALKSYVSMAKMKELQPQMEALKEAAGDDRQKMQQGMMELYKKEKVNPAAGCLPILLQIPIFFSLYKVIFVTIELRQAPWFGPFRDLSMPDPTSIMNFFGWLPWAGPEAGSLTATILIGILPLLLGISMWLQQKLNPAPTDPTQAMIFAWMPWVFMFMLGSFASGLVVYWIANNTITFTQQYIIMRSHGYKPDVFGNIKSGFARRAKADKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PRMA_LATSS
Sequence: MEWTKVTVATVNEAVEAIANILTEAGAEGIQIEDASINDTLVGDVAAVSAFFPETVFVPEKLPLIRQRVLQLTEFGLSIGEGSVNLQQVADDDWATAWKKYYQPTRLTRFLTVVPSWTDYQPTDEREALIRMDPGMAFGTGTHPTTHLSVQMLEMVLRGGEQLIDVGTGSGVLSIAAAHLGVQDIRAYDVDQVAVDAAVANFDLNPVTQGIIAKPNDLLHGITGAADVIVANMLPVVLVPLIPQVPALLKEGGHLLLAGIITEKEAVIRETLSANGLMVEESLHMGDWVGLITRLKTDED
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_ROSDO
Sequence: MLKTRIIPCLDVADGRVVKGVNFVDLRDAGDPVDAAIAYDAAGADELCFLDITATHENRATMFDVVTRTAEHCYIPLTVGGGVRSVSDVRALLLAGADKVSFNSAAVANPDVVAQAADQFGSQCIVVAIDAKTTSPGKWEIFTHGGRKPTGIDAVAFAQTVTAKGAGEILLTSMDRDGTRAGFNLPLTRAISDAVNVPVIASGGVGTLDHLVEGVTKGGASAVLAASIFHFGDYTIAQAKQHMSDAGIPMRLI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_STRPQ
Sequence: MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHLRKAGLVSSGDFKRIKAMVTGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: IRAK2_RAT
Sequence: MACYIYQLPSWVLDDLCRNIDTLSEWDWMQFASYVITDLTQLRKIKSMERVQGVSITRELLWWWSMRQATVQQLVDLLCHLELYRAAQIVLSWKPAPDSLSPLSAFPEAVKPGPVATSGRNLKDDQKKGQPVKPCSFLSSGTTMAGAQQQASCQRPCEEDAPCSLKTDVPDSLQSKYCSTSIPKQEKLLNLPGDRLFWSEADIVQATEDFDQSHRISEGTFADIYRGQRNGVAFAFKRLREVTGSSPGSMDRFLQAEMQLCLRCCHPNILPLLGFCTGRQFHSLIYPYMANGSLQDRLWAQGDSDMLSWPQRASICSGLLLAVEHLHSLDIIHSNVKSANVLLDQHLNPKLAHPVAHPCPTNKKTKYTVMKTHLFQASAAYLPENFIRVGQLTKQVDIFSCGIVLAEVLTGIPAMDKDRSPVYLKDLLLSEIPSNTSSVHSRKTSMGKVVVKEICQKHLERKAGLLPEACAETWATAVSVCLRRREASLEEARVSMAGVEEQLRGQLSLPWSRVSEDTGSSSNTPEETDDVDNSSLSVPSSVMVVSCARVSSPPPSMGNGTAQPSTSGRQEADSSSEACAGPQPPQEATETSWKIEINEAKRRLMENILLYKEEKLDSVELFGP
What is the function of this protein?
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
What are the official names of this protein?
Interleukin-1 receptor-associated kinase-like 2, IRAK-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
Protein: FTHS_OENOB
Sequence: MKSDIEIDHSIKALPITEIGKQIGLSDSQLIPYGHDKAKIDAYSIANMPRQGKLVLVTSINPTPAGEGKTTVTIGLVDAINRLGKSAIGALREPSMGPVFGLKGGATGGGYAQVIPMEDINLHFTGDIHAVSAAHNLLAAVIDNHLHQGNELKIDPENIYWRRVLDMNDRALRQITLGKGRVNGPERNSGFDITASSEIMAVLTLSKNLFDLKKRLSRIVVALDVQGKPVTVADLKVAGALTAILKDAINPNLVQSLEHSPFIIHGGPFANIAQGTNSVVATDAALKLADFAVTEAGFGSDLGGEKFMDVKVPVLGKEPDAVVIVATVKALKFHGGVALDHLSDKNVDAVRNGLDNLNRHLEAMTHYGKPVVVALNKFLDDDMEEIQLIKNFVEGEKKLQFEIVTSFVDGFEGSLDLAKKVIEATDNQRFFMPLYQADDSIENKIQTIVEKIYGGKDFELSDRAKKDLAEVKENGWGKLPVVIAKTPNSLTDDSKIHGAPTGFTIHIRRFIPKIGAGFIVAMAGKVLMMPGLGKNPAAEKIDVDENGKISGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: TRHO_PECCP
Sequence: MPVLHNRISNEELKARMLAETEPRTTVSFYKYFTIDDPKAFRDRLYIQLEQCKVLGRIYIATEGINAQISVPNNQFDAFKAVLFSAHPALDQIRLNIALEDDGKSFWVLRMKVRERIVADGIDDPTFNPANVGQYLKADQVNAMADDPDTVFVDMRNHYEYEVGHFENALEVPSDTFREQLPMAVEMLDEARDKNIVMYCTGGIRCEKASAYMLHHGFKNVYHVEGGIIEYARQAKAQGLPLKFIGKNFVFDERMGERISDDVIAHCHQCGASCDSHTNCRNEGCHLLFIQCPTCAAKYEGCCSTQCLDEMKLPLEEQRAIRSGRENGMKIFNKSKGLLQSTLHIPAPEVKDKAE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: SUGP1_HUMAN
Sequence: MSLKMDNRDVAGKANRWFGVAPPKSGKMNMNILHQEELIAQKKREIEAKMEQKAKQNQVASPQPPHPGEITNAHNSSCISNKFANDGSFLQQFLKLQKAQTSTDAPTSAPSAPPSTPTPSAGKRSLLISRRTGLGLASLPGPVKSYSHAKQLPVAHRPSVFQSPDEDEEEDYEQWLEIKVSPPEGAETRKVIEKLARFVAEGGPELEKVAMEDYKDNPAFAFLHDKNSREFLYYRKKVAEIRKEAQKSQAASQKVSPPEDEEVKNLAEKLARFIADGGPEVETIALQNNRENQAFSFLYEPNSQGYKYYRQKLEEFRKAKASSTGSFTAPDPGLKRKSPPEALSGSLPPATTCPASSTPAPTIIPAPAAPGKPASAATVKRKRKSRWGPEEDKVELPPAELVQRDVDASPSPLSVQDLKGLGYEKGKPVGLVGVTELSDAQKKQLKEQQEMQQMYDMIMQHKRAMQDMQLLWEKAVQQHQHGYDSDEEVDSELGTWEHQLRRMEMDKTREWAEQLTKMGRGKHFIGDFLPPDELEKFMETFKALKEGREPDYSEYKEFKLTVENIGYQMLMKMGWKEGEGLGSEGQGIKNPVNKGTTTVDGAGFGIDRPAELSKEDDEYEAFRKRMMLAYRFRPNPLNNPRRPYY
What is the function of this protein?
Plays a role in pre-mRNA splicing.
What are the official names of this protein?
SURP and G-patch domain-containing protein 1, RNA-binding protein RBP, Splicing factor 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURA_RHIME
Sequence: MTNVVVVGSQWGDEGKGKIVDWLSERADIVVRFQGGHNAGHTLVIDGVSYKLSLLPSGVVRPGKLAVIGNGVVIDPHALLAEIDKLAAQGVKVTPENLRIADNATLILSLHRELDGIREDAASNSGTKIGTTRRGIGPAYEDKVGRRAIRVMDLADLDTLPAKVDRLLTHHNALRRGLGEAEISHQAIMDELSSVAERVLPFMDTIWLLLDRERRKGARILFEGAQGTLLDIDHGTYPFVTSSNTVAGQAAAGSGMGPGSLGYILGITKAYTTRVGEGPFPTELDDEIGRFLGERGHEFGTVTGRKRRCGWFDAALVRQSVAANGITGIALTKLDVLDGLDELKICVGYTLDGQQIDHLPASQAQQASAKPVYITLEGWKESTVGARSWADLPAQAIKYVRQVEELIGAPVALLSTSPERDDTILVTDPFED
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMCT_HELPJ
Sequence: MQEYHIHNLDCPDCAAKLERDLNKLDYVKKAQINFSTSKLFLDTSDFEKVKAFIKQNEPHLSLSFKEAAEKPLSFTPLIATIAVFLGAILILHLEPSPFIEKAVFVVLALVYLISGKDVILGAFRGLRKGQFFDENALMLIATIAAFCVGAYEESVSIMVFYSAGEFLQILAIARSKKSLKALVDVAPNLAYLKKGDTLVSVAPEDLRINDIVVVKVGEKVPVDGVVIKGESLLDERALSGESMPVNVSERSKVLGGSLNLKAVLEIQVEKLYKDSSIAKVVDLVQQATNEKSETEKFITKFSRYYTPSVLFIALMIAVLPPLFSMGSFDEWIYRGLVALMVSCPCALVISVPLGYFGGVGAASRKGILMKGVHVLEVLTQTKSIAFDKTGTLTKGVFKVVDIVPQNGHSKEEVLHYASCSQLLSTHPIALSIQKACEEMLKDDKHQHDIKNYEELSGMGVKAQCHTDLIIAGNEKMLDQFHIAHSPSPENGTIVHVAFNQTYIGYIVISDEIKDDAIECLRDLKAQGIENFCILSGDRKSATESIARTLGCEYHASLLPEEKTSVFKTFKERYKAPAIFVGDGINDAPTLASADVGIGMGKGSELSKQSADIVITNDSLSSLVKVLAIAKKTKSIIWQNILFALGIKAVFIVLGLMGVASLWEAVFGDVGVTLLALANSMRTMRA
What is the function of this protein?
Couples the hydrolysis of ATP with the transport of cadmium, zinc and cobalt out of the cell.
What are the official names of this protein?
Cadmium, zinc and cobalt-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SET1_COCIM
Sequence: MSRAPAGFADFFPTAPSVLQKKRSKAAQDRHAANTPKAADPLPNLGLSSTPDIKGGVGTSADNPVRAVGERSAETTLALGDTNGATSSSSLSTGSSGFFSASAPPGVAKPNGISSCALTPLTNTDSSPPCKIESPLGSKSGSTDAAPQLAPTCEAHGGPEPVTITPLHTPPTPRVQARPANSEVKGHKITYDPDLDRKFPSKARRRKPQYETFGVDDEKDPPPCDPRMAIANYTRGAACKQKTKYRPTPYILRPWAYDPTTSVGPGPPTQIVVTGFDPLTPIAAISALFSSFGDIGEINNRTDPMTGRFLGVCSIKYKDSRAFRGGISLSASQAVRRAYLECKKEQRIGTRRIRVELDRNGVVSGRMVAKLITAQKAEFPSLEESRKESVGDNDNRLPIGDGAKKDNEQSKDNLPPSTAPKGPSGRSSLHPSLLAPDGPRAVLKSPVPSRIEETPILQQIKRDPYIFIAHCYVPVLSTTVPHLERRLKLYDWKAVRCDKTGYYIIFENSRRGELEAERCYRMCHMTALFTYVMNMECQPYGNPNYERSPSPERIKAEKREKAKRERLHREMELDIEEEKRLRVENLDPAREALSVLIIELRDKLLDDVKSRVAAPALYDFLEPDRHNAKRQQLGIPAPEGTGRPSFRIDASTDGTVVHSQPDAYSRHHRPGGVSSLNVLALPRIRKVKGFEQGNAVYIDERRRAKPRKREFRPLYHRLQQLHEIEDSDDDQQVSFARDTEEVESRPLSRLSSESAESDNEDDLMRKSPSLLDAKPLDVPLPESESLAGGIEQSGLPDREKSIIEELERGINTLPTSSKKRKRLIEELATRKKRKEVDNLFELDAKPLESLVEETAQEALPADSTDALRTVTPVLKDKKRKVKGQSGKQIFEERQAPKRKEIDSTQPLLFEESVELLPEGEIEISEPAIEELKPEVEWGVSTDEPRPTAEDDDTIVLDLDGWQSLIKDDEDINFLKKALSEHLAADIGNLAAWTWKHKEIKAINRGGDRGPVHSETRIDGYYVPNPSGSARTEGRKRIRESEKSKYLPHRIKVQKAREERLAKAKNDPHAAAAEAARLLAAKSLSKSTSRSTRVNNRRLIADINAQKQALPMQNGDSDVLRFNQLKKRKKPVRFARSAIHNWGLYAEENISANDMIIEYVGEKVRQQVADMRERRYLKSGIGSSYLFRIDENTVIDATKRGGIARFINHSCTPNCTAKIIKVDGSKRIVIYALRDIDRDEELTYDYKFEREWDSDDRIPCLCGSAGCKGFLN
What is the function of this protein?
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-4 specific, COMPASS component SET1, SET domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ATPB_ALIFM
Sequence: MTTGKIVQIIGAVVDVEFPQGEVPRVYDALNVVDAQERLVLEVQQQIGGGVVRCIVMGSSDGLRRGLTVENTGAPISVPVGTKTLGRIMNVLGDAIDECGDIDAEEHYAIHREAPSYEEQSNSTELLETGVKVIDLVCPFAKGGKIGLFGGAGVGKTVNMMELINNIALQHSGLSVFAGVGERTREGNDFYFEMQEAGVVNIEKPEESKVAMVYGQMNEPPGNRLRVALTGLTMAERFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKQGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLNRNIAAMGLYPAIDPLDSTSRQLDPLVVGQEHYDVARGVQSTLQRYKELKDIIAILGMDELSEEDKQVVSRARKIEKFLTQPYHVAEVFTGDPGIYVPLKDTLAGFKGLLAGDYDDVPEQAFMYCGKIEDALEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SAES_STAEQ
Sequence: MTIFSIRSQIIIGVISSVILTTIILVIAYKLMWFNGHMTLTLAITTMITSCLTLSICSIFINPLIQKIKQFNIKTKQFINHEKFIDDETFQSPREIKELNDSFNKMAYEINNQMNMIKNEQQEKTEIIQNLAHDLKTPLAGIRSYSEGLRDGVISDPQEVHEAYEILIKQANRLSILFDDITHVINLNTGRSYPLELIQLDQLLVNILQPYEQHIKQENRTLEVNFCTDIDAFYQYRPPIERILTNLLDNALKFSNSGSRIDIIISECKENDVISISIKDEGIGIVPELQSRIFERTFRVEDSRNTKTGGSGLGLYIANELAQQIDASITVQSDLDIGTTMTLTLKKFQFKK
What is the function of this protein?
Member of the two-component regulatory system SaeR/SaeS.  Probably functions as a membrane-associated protein kinase that upon sensing the appropriate signal, autophosphorylates and in turn activates the cytosolic response regulator SaeR (By similarity).
What are the official names of this protein?
Histidine protein kinase SaeS, Sensor protein SaeS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRLF3_DANRE
Sequence: MSIEAEALLQEAKESIEAAQNYRSELQQRLHGLSQARKQVRGSASQTRKALQRHFQELQTAVSRLLIDRLNGLLQEVDNIELDSVSPLDDCQKLIEHGVSTADELLREGEAAIRCSINETEDKLGSFTKKALQIQLDSLPEVPSLVDVPCLSAQLDDSLLHMFRAHVARHGSVASHPPVQIEELVERPGGVLVRWCKVDDDFSPQDYRLQFRRSNSSQYEDAYIGKDTEFLVLHLDPHVDHLFRVCARGEGRTEWSPWSIPQTGYTTLAPHEWCPGVDGYILSSRKNIAMRSDSSAPGHGGVLYSNSPTYFCGQTLTFKITAAGQTDKRDSLGVCADSRTDTDSLQRDQAVCISTNGAVFVNGKEMTNQLPAITVGSSVTFDMEVVSLFPVNNNNPSDGGNFKLRVTIGSGNREVVFDWLLDQVLDSLFFGCSFTHPGWKVLVF
What is the function of this protein?
May play a role in the negative regulation of cell cycle progression.
What are the official names of this protein?
Cytokine receptor-like factor 3, Clf-3 protein.
What is the protein family that this protein belongs to?
Belongs to the cytokine receptor-like factor 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_SALHS
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNU8_YEAST
Sequence: MSANEFYSSGQQGQYNQQNNQERTGAPNNGQYGADNGNPNGERGLFSTIVGGSAGAYAGSKVSNNHSKLSGVLGAIGGAFLANKISDERKEHKQQEQYGNSNFGGAPQGGHNNHHRQDNNNNNGGFGGPGGPGGQGFGRQGPQGFGGPGPQEFGGPGGQGFGGPNPQEFGGPGGQGFGGPNPQEFGGQGRQGFNGGSRW
What are the official names of this protein?
Uncharacterized protein YNL208W.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RLMG_PSEMY
Sequence: MPIFTTPFASLELLRQPHQPNEPLQAFDAADEYLLNHLHEQGLRAEDSLLLLNDSFGALACSLAGRCQVTSSSDSHLGFIALENNLAGNGLNRDAVRFLPSSETPQGPFDWVLIRVPKTLALLEEQLIRLHGQLAPGARVVAAAMVKHLPRAAGDLLEKYIGPVQASLAVKKARLLLATPEAKAAPHSPYPTRYRLDKPALELINHANVFCRDGLDIGTRAFLPHLPRHLDARRVADLGCGNGVLGIAYALGSPQAQLTLVDESYMAVQSARENWAAALGERPATIRAGDGLAEQPAGSLDLVLCNPPFHQQQVVGDFLAWRMFQQARAALVTGGELWIVGNRHLGYHAKLARLFRGVEQVAANPKFVVLKASK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_METCA
Sequence: MESWVFERGSLTRRLKAACGADFNVRVIRQGFAHPFPDEALLLKLRSGRRALVREVELRSRERRLVLARSVLPAQTLKGAGRRLAHLGNRPLGEILFASRRPRRHGFEAALAEDRHWRPAVRAGSGSAGPVWGRRSLYSIAGRPLLVAEFFLPAVLSVPESA
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_CUSGR
Sequence: MTDTTGRIPLWMIGTLAGILVISLIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.