PharMolix/UniProtQA huggingface dataset:
Protein: YXXB_BACSU
Sequence: MAVKDRYMSKIKQETKPWIKRFGRLGYFAFGGVFILLGVLAFMTAAGAGRAKDSSGALQTLSRMPYGSLLLFFIGIGLIGYVIWMVLSAIKDTEGHGNSRRGLSRRIGNFFSAAVYTSIAWNALRFVFGQGDGGTSEQTWSAYVLAQPFGQWLTGLTGAGFIVFAIVQFMKGVRAAFMKEFDTSKMNKQMICITKNTGRAGNIARAIIFSAIGYFLIKTAMTADPDDTRGFDGALAELAQQPHGKLILSILALGLILYGMYAIMKGIYQHMTWEK
What are the official names of this protein?
Uncharacterized protein YxxB.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPR4_ARATH
Sequence: MNFRNLIASGSRLGKRFCATVFAPASATGIVEASVSSPAAANVVEASVSSPAAENGVRTSVAAPTVASRQRELYKKLSMLSVTGGTVAETLNQFIMEGITVRKDDLFRCAKTLRKFRRPQHAFEIFDWMEKRKMTFSVSDHAICLDLIGKTKGLEAAENYFNNLDPSAKNHQSTYGALMNCYCVELEEEKAKAHFEIMDELNFVNNSLPFNNMMSMYMRLSQPEKVPVLVDAMKQRGISPCGVTYSIWMQSCGSLNDLDGLEKIIDEMGKDSEAKTTWNTFSNLAAIYTKAGLYEKADSALKSMEEKMNPNNRDSHHFLMSLYAGISKGPEVYRVWESLKKARPEVNNLSYLVMLQAMSKLGDLDGIKKIFTEWESKCWAYDMRLANIAINTYLKGNMYEEAEKILDGAMKKSKGPFSKARQLLMIHLLENDKADLAMKHLEAAVSDSAENKDEWGWSSELVSLFFLHFEKAKDVDGAEDFCKILSNWKPLDSETMTFLIKTYAAAEKTSPDMRERLSQQQIEVSEEIQDLLKTVCP
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g02370, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYS_STRMK
Sequence: MLDPALLRHQPADLAERLRTSRGFELDVSALESLEADRKRIQVRTQELQSLRNSRSKAIGQAKAKGEDVSAIMAEVAAFADELKASEVALDELREKIEAISMGIPNLPADDVPAGADENDNVEQSRWGTPRQFDFKVLDHVELGARNGWLDGETAAKLSGSRFTVLRGPIARLHRALAQFMVDLHTGEHGYEETNVPLLVNADSLRGTSQLPKFEDDLFKTAVGDSTRYLIPTSEVPLTNIVRDEIVDAERLPLRMTAHSMCFRAEAGSGGRDVRGMIRQHQFEKVELVSISRPEDSDAEHQRMTRCAEVVLEKLGLPYRKVLLCTGDMGFSAVKTYDLEVWLPSQETYREISSCSNCGDFQARRMQARWRNPATGKPELAHTLNGSGVAVGRAMIAVMENYQNADGSITVPEALRPYMGGLETIA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_XANOR
Sequence: MTTLDESLALIGRGAEEILKLDQLEARLTSGVPLRVKAGFDPTAPDLHLGHTVLLNKMRQFQQLGHQVIFLIGDFTGMIGDPSGKNATRKPLSREDVLANARTYEEQVFKILDRERTEVRFNSEWFGQMSAADMIKLSAQHTVARMLERDDFAKRFGSQQPIAIHEFLYPLVQGYDSVALRADVELGGTDQKFNLLMGRGLQEHYGQAPQIVLTMPLLEGLEGVAKMSKSLGNYIGINEPAIDIVTKTMKIGDELTWRWIDLLSLDISVAEAVRLKEQVTSGELHPREVKLRLARELATRFHDAATAEQAIAGWHAVVTGQGDTSLLPLQEVVVPAEGLRIASLLTAAGLTPSNSEATRKLKERAVKIDGEVLEDATRVFTQGFEGVIQVGKRNFARVSLVIG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG52_ALHV1
Sequence: MDPKNLTVEQLAAELTKLQMENSHLKRKLRRSVGGPPKEPPKPRELTEPERQLVLARWHNRFSSRSSELLRRQLDKLTATLVTEEDIDEVLKNADFRLHFRPDPSENPEKKLSKEKRRTARGQQQ
What are the official names of this protein?
Uncharacterized gene 52 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BLRF2 family.
Protein: KAD_ECO7I
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRAALEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_THENN
Sequence: MRCPFCGSMDTRVLDSRPTLDGAAIRRRRECISCGRRFTTYERYEEAPVLVIKKDGRREKFDRNKIKNGMIKACEKRPVTYDQIEEAVNRICLKLREEGLFEVETKKIGELVMEELKKLDQVAYVRFASVYRDFREVDQFLEIVKELKREKEGEGK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: UNG_PSHV1
Sequence: MANDERVATGEDRAWGRLGVAELRIDAASVAPNDPTEDREVVLPIPGPAVSPIPRLTQPPRSSPPRPDAPSDLPRAQREPTKRSPATAGPTEDPNFADKIFKQAAPARKKPRFMPPPKLICGGVTDVTAELPAPSWDRVAEEFGIPDSWKNILAPLVETQRFAKTLQSYNGAKKSGNVLPSQDQIFAWARYCAPHEVKVIIVGQDPYPTEGDAHGLAFSVPVGRRVPPSLRRVFAALKDCYGDGFPTPSSGSLIAWAKQGVLLLNRHLTVERGLPRSHVSMGWDKLTFGVIKTLANDNPRMAVMLWGYDAKTFVPKLPSKHLRLEYSHPSTSTRRPFDCRHFIEANKFLEEGGLQAVVWRLP
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RSXA_SALDC
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLDLIYLRTLAFILVIAVVVQFTEMVVRKTSPALYRLLGIFLPLITTNCAVLGVALLNINLGHHFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FER2_RICFE
Sequence: MSGKIKVTFIVNDGEEKTVEAPIGLSILEITHSNDLDLEGACEGSLACATCHVILEEEFYNKLKKPTEAEEDMLDLAFGLTDTSRLGCQIILTEELDGIKVRLPSATRNIKL
What is the function of this protein?
Ferredoxin are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
What are the official names of this protein?
2Fe-2S ferredoxin, Adrenodoxin-like protein.
What is the protein family that this protein belongs to?
Belongs to the adrenodoxin/putidaredoxin family.
Protein: RLME_SALTY
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_SALSV
Sequence: MANQPSAEELKKKLSEMQFYVTQDRGTEPPFTGRLLHNKRDGVYHCLVCDTPLFHSHTKYDSGCGWPSFYQPVSEEAIRYIDDFSHGMQRVEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLAFSDEKNGDQLKG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: AROQ_LEGPC
Sequence: MKKILVLHGPNLNLLGSREPSIYGHASLTEINGDLIQEADNAGIRLSCFQSNAEAELIQAVHQAGIDKINYIIINPAAFTHTSIALRDALSAVAIPFIEVHLSNIFSRETFRHHSYFSDIAVGVISGLGTKGYLLALQAIIKELK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: KM11_TRYCR
Sequence: MATTLEEFSAKLDRLDAEFAKKMEEQNKKFFADKPDESTLSPEMKEHYEKFEKMIQEHTDKFNKKMHEHSEHFKAKFAELLEQQKNAQFPGK
What is the function of this protein?
May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules.  May be involved in parasite mobility and attachment to the surface of the host cell.  Behaves as a strong immunogen during infection.
What are the official names of this protein?
Kinetoplastid membrane protein 11, KMP-11.
What is the protein family that this protein belongs to?
Belongs to the KMP-11 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: NORV_SALTY
Sequence: MSILVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRSEIDLADIDYIIINHAEEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFKVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYMTGDAVLFSNDAFGQHYCDERLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWATDYQEDRITIFYDTMSNNTRMMADAIAQGINEVDPNVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDLDALELCRQHGRDIARQWALAPLPETTQQIAPVEETITCTAADLGPKMQCSVCQWIYDPALGEPLQDVAPGTPWNDVPDNFLCPECSLGKDVFDVLATEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAFD_ECOLU
Sequence: MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNFSLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK
What are the official names of this protein?
UPF0294 protein YafD.
What is the protein family that this protein belongs to?
Belongs to the UPF0294 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDC61_METAC
Sequence: MIKAQSLDGLFEKLLDGKSIFKNKEVLRPSYTPDLLLHRNEQINSLATILVSALRGETPSNVLIYGKTGTGKTAVTRYVGKELERVSEDKSLFCSVVYINCEVIDTQYRLLANLARHFEEEVPMTGWPTDQVFMKFKEAIDARDQVIIIILDEIDKLIKKGDDVLYNLSRINTDLRKAKVSMIGVSNDLKFTEFLDPRVKSSLGEEELIFPPYDAEQISDILKQRAKMAYNDGVLGEMVIPLCAAFAAQEHGDARRALDLLRVSGEIAERENQPQVLEEHVRRAQEKIEIDRVVEVVRTLPTQSKLVLYSIILLRSRGREGKNVTTGEMYNVYRQLCHHIDVDILTQRRVTDLMSELDMLGIVNAVVVSKGRYGRTKEISLSVPVENTRKVLLEDYRLKPLVDFKTAVFNKMFS
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 1.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: MIRO2_CHICK
Sequence: MKRDVRILLLGEAQVGKTSLIMALVGEEFPEEVPPRAEEITIPADVTPEKVPTHIVDYSESEQTEDELQEEIAKANVVCVVYDVTKEATIEKIRTKWIPMVNGGAEKGARIPIILVGNKSDLQMGSSMEVILPIMNQFSEIETCVECSAKNLKNISELFYYAQKAVLHPTAPLYDPEEKQLRPACSRALTRIFNLSDQDNNQILSDDELNYFQKSCFGNPLAPQALEDVKMVVWKNTTDGVQDNGLTLNGFLFLNTLFIQRGRHETTWTILRRFGYDDELELTDDYLYPQFRLPPGCSTELNHLGYQFLQRLFEKHDKDQDGALSPAELQNFFSVFPCMPWGPELYNTVCTTDKGLLSLHGFLCQWTLIAYLDVRHCLECLGYLGYPILSEQDSQTQALTVTREKRIDLEKGQTQRNVFLCKVLGARGAGKSAFLQAFLGRSLAAQRESPGEPSPYTINTVQVNGQEKYLILHEVSAETQFTKPSDAACDVACLIYDLSDPKSFSYCASIYKQHYMDSQIPCVFVASKTDLPEASQQPGLSPAEFCYKHCLPPPFLFSCHSQGPPGTAIYTKLATAATFPHLNAVELGAASFWLRVALGAAVTALVGFTLYRVLAKNK
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking.  Probably involved in control of anterograde transport of mitochondria and their subcellular distribution (By similarity).
What are the official names of this protein?
Mitochondrial Rho GTPase 2, MIRO-2, Ras homolog gene family member T2.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: SYM_AZOVD
Sequence: MPEARQILVTSALPYANGSIHLGHMLEYIQTDIWVRFQKQRGNQCVYVCADDAHGSAIMLRAEKEGITPEQLIAYVQAEHSADFADFLVDFDNYHSTHAEENRALSEAIYLRLRDAGHIATRSVTQYFDPEKGMFLADRFIKGTCPKCGAEDQYGDNCEKCGATYEPTELKDPRSAISGATPVLKDSKHFFFKLPDFEAMLKEWTRSGTLQEAVANKIAEWLDGGLQEWDISRDAPYFGFEIPDEPGKYFYVWLDAPIGYMASFKNLCARRPELDFDAFWCKDSKAELYHFIGKDIVNFHTLFWPAMLEGAGFRKPTAVNVHGYLTVNGQKMSKSRGTFIKARTYLDHLNPEYLRYYYASKLSRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNAGLMVDANPEPELWEAFQVAAPAIAEAYEGRDFGRAMREIMALADRANAWIADKAPWALNKQEGKQTEVQEICAFGINLFRQLVIFLKPVLPNLATAAEAFLNVAPLTWQDHTLRLANHPLNPFTPLMTRIEPAKIDAMIEASKEDLAAQNSEAAAPQGNGELVKEPLAPEIDFNAFAAVDLRIALIEKAEFVEGADKLLRLTLDIGDAKRNVFSGIKSAYPEPSELEGRLTLYVANLAPRKMKFGLSEGMVLAAGPGGSEIFLLSPDAGAKPGQRVH
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB1_PROMA
Sequence: MHSKLNIQSKQLYKIFLLIVGSILGAILRWKLNNYFWVNISGAALLGLIVGLRAGSRIQFFLVIGFCGSFTTFSGWILDVFDLFRTGFFWKAAGLICSNLLGGFTALSVTFWIGRKIRHLFIPQ
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LSPA_ECO45
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIMD1_HUMAN
Sequence: MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARWEVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYYDNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQRVSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGSQQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLEALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKRPSSTALHQHHF
What is the function of this protein?
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration.  Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity.  Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A.  Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription.  Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1.  Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements.  Regulates osteoblast development, function, differentiation and stress osteoclastogenesis.  Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts.  May act as a tumor suppressor by inhibiting cell proliferation.
What are the official names of this protein?
LIM domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
Protein: MURG_NOVAD
Sequence: MTTVSRHYVLAAGGTGGHLIPAFALAVELDRRGHHVALVTDERGAKIPGKPDFLPAHVLPAGRLGKNPVALFKGLRAIWQGRAMALRLFESFEPSCVIGFGGYPALPALLAAHAARIPTVIHEQNAVLGRVNRLLAKRVDAIATAYGEVDRLDPKLWGKVHRVGNPVRPDVLALRGEPFPEFTEDSLFRVLVTGGSQGASILSEVVPDGLAMLPPALRHRLQVTQQCRPEDLEVVRARYAAHEIPAELGTYFEDMQARLAGTHLFIGRAGASTIAELTAVGRPAILVPLPIATDDHQAANTREVVAAGGARAIRQSGFTPKELAKQIQAMAQHPHTLANAAHAAWNCGLPNAVKDLADLVESFGASPIMDVIRLDSTVSAASGQEQLA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HPRK_FUSNN
Sequence: MYTYTTIREIVDKLNLEILNEGNLDLKIDIPNIYQIGYELVGFLDKESDELNKYINICSLKESRFIATFSKERKEKVISEYMSLDFPALIFTKDAIITEEFYYYAKRYNKNILLSNEKASVTVRKIKFFLSKALSIEEEYENYSLMEIHGVGVLMSGYSNARKGVMIELIERGHRMVTDKNLIIRRVGENDLVGYNAKKREKLGHFYLEDIKGGYVDVTDHFGVKSTRIEKKINILIVLEEWNEKEFYDRLGLDVQYEDFVGEKIQKYIIPVRKGRNLAVIIETAALTFRLRRMGHNTPLEFLTKSQEIIERKKKEREEYMNTNRLPVTKLINEFDLEIKYGEDKVSSTYINSSNVYRPSLSLIGFFDLIEEVKNIGIQIFSKIEFKFLENLPPIERVNNLKKFLTYDIPMIVLTVDANPPDYFFDLVSKSGHILAIAPYKKASQIVANFNNYLDSFFSETTSVHGVLVELFGFGVLLTGKSGIGKSETALELIHRGHRLIADDMVKFYRNTQGDVVGKSAELPFFMEIRGLGIIDIKTLYGLSAVRLSKTLDMIIELQAVDNSDYMSAPSAHLYEDVLGKPIKKRILEISSGRNAAAMVEVMVMDHMSGLLGEK
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr) (By similarity).
What are the official names of this protein?
Putative HPr kinase/phosphorylase, HPrK/P.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: CNBA_COMTE
Sequence: MPTSPFIDDLIRDRRTKRGFLDQPVPIEMVKDILSVAKYTPSSSNTQPWRCYVLTGEARERVTTAAVEAYRGAPEGLKPEYSYFPEPLHEPYATRFNSFRGQLGDAEGCCRSDITGRRRYVERQFRFFDAPVGLIFTMDRRLEWASFICYGCFLQNIMLAAKGRGLDTCPQGLWSLQHPVLRTELNLPDDQMVVAGMSLGWADNSMAVNQMSMSRVELEEFTTFVHE
What is the function of this protein?
Involved in the biodegradation of chlorinated nitroaromatic compounds.  Catalyzes the reduction of 4-chloronitrobenzene to yield 1-hydroxylamino-4-chlorobenzene.  Probably also able to catalyze the two-electron reduction of nitrobenzene (NB) to produce a nitrosobenzene (NOB) intermediate, which is immediately reduced to hydroxylaminobenzene (HAB) by a second two-electron transfer.
What are the official names of this protein?
Chloronitrobenzene nitroreductase, Nitrobenzene nitroreductase.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: OTC_STRPC
Sequence: MTQVFQGRSFLAEKDFTRAELEYLIDFSAHLKDLKKRGVPHHYLEGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEEEIVTLAEGYAKESGARILITEDADEAVKGADVLYTDVWVSMGEEDKFKERVELLQPYQVNMDLVQKAGNDKLIFLHCLPAFHDTNTVYGKDVAEKFGVKEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_RHOPS
Sequence: MSAPEPKITPELVASHGLKPDEYQRILDLIGREPSFTELGIFSAMWNEHCSYKSSRIHLRGLPTKAPWVLQGPGENAGVIDIGDNQAVVFKMESHNHPSYIEPYQGATTGVGGILRDVFTMGARPIACLNALSFGAPEHPKTRHLVSGVVAGVGGYGNSFGVPTVGGQTRFHTRYDGNILVNAMAVGLADADKIFLAAASGVGMPIVYLGSKTGRDGMGGATMASAEFGEGSEEKRPTVQVGDPFAEKLLLEACLEIMANDCVIAIQDMGAAGLTCSAVEMGAKGDLGVDLDLDAVPTRETGMTAYEMMLSESQERMLMVLKPEKEKEAEAIFRKWGLDFAVVGYTTPTKRFVVKHGGKAMADLPIKELGDEAPLYDRPWVESPKLPVIHAREVNAPNSIADALEKLLATPDLCSKRWVWEQYDHVIGGNTLQRPGGDAAVVRVQDGPKGLALTVDVTPRYCEADPFEGGKQAVAEAWRNITAVGGKPLAITDNLNFGNPERPEIMGQFVGCLKGIAEACIAFDFPVVSGNVSLYNETSGRGILPTPSIGGVGLLDDFTKSATLAFKAEGEAILLIGETHGWLGQSVYLRDICGREEGAPPPVDLACEKRHGDVVRGMIHAGTATAVHDLSDGGLLVALAEMALAGSIGASLEAPPDGIVPHAWWFGEDQGRYLVTVKEDDLLTVLSKMKSVGVSCEQIGRTAGHTLKIEGERALDLKALRHAHEHWLPDYMGGKN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR12_BARVE
Sequence: MPTIKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.