PharMolix/UniProtQA huggingface dataset:
Protein: FOLC_MOUSE
Sequence: MSWARSRLCSTLSLAAVSARGATTEGAARRGMSAWPAPQEPGMEYQDAVRTLNTLQTNASYLEQVKRQRSDPQAQLEAMEMYLARSGLQVEDLNRLNIIHVTGTKGKGSTCAFTERILRNYGLKTGFFSSPHMVQVRERIRINGKPISPELFTKHFWCLYNQLEEFKDDSHVSMPSYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAFDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIAWQKGGIFKPGVPAFTVVQPEGPLAVLRDRAQQIGCPLYLCPPLEALEEVGLPLSLGLEGAHQRSNAALALQLAHCWLERQDHQDIQELKVSRPSIRWQLPLAPVFRPTPHMRRGLRDTVWPGRTQILQRGPLTWYLDGAHTTSSVQACVHWYRQSLERSKRTDGGSEVHILLFNSTGDRDSAALLKLLQPCQFDYAVFCPNVTEVSSIGNADQQNFTVTLDQVLLRCLQHQQHWNGLAEKQASSNLWSSCGPDPAGPGSLLLAPHPPQPTRTSSLVFSCISHALLWISQGRDPIFQPQSLPRNLLNHPTANSGASILREAAAIHVLVTGSLHLVGGVLKLLDPSMSQ
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Dihydrofolate, tetrahydrofolate, 5,10-methylenetetrahydrofolate, 10-formyltetrahydrofolate and 5-formyltetrahydrofolate are the best substrates.  Folic acid and 5-methyltetrahydrofolate can also act as substrates.
What are the official names of this protein?
Folylpolyglutamate synthase, mitochondrial, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion inner membrane. Mitochondrion matrix. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: CYB_HETBL
Sequence: MLSSLRKSHPVLKIVNGALVDLPVPVNLSVWWNFGSLLGLCLIVQVLSGLFLAMHYTSCVEMAFDSVVHIMRDVNYGWVLRYIHANGASFFFICLYFHVARGIYYGSYVLMETWNIGVVLLFLVMGTAFVGYLLPWGQMSFWGATVITNLVSAIPYVGEMVVYWIWGGFSVDNATLSRFFCFHFLLPFVLMAMVVMHFLFLHQTGSNNPLGINGNLDKIPFHQYYSYKDLLGFFVMLLLLIEFSMLFPNALGDSENFIPANSLVTPLHIKPEWYFLFAYAILRSIPSKLGGVISLVMSICVLFFLPFLHIKGCRGCSYNVFMQLNFWLMIGCFFLLTWIGGCPVEYPYEFIGQVLSVMWFGVFLVRPFLDLLWLYILDY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATPL_STRZP
Sequence: MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLMFLGVAFIEGTFFVTLVFSFIIK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2563_ACIAC
Sequence: MDPKLLELLVCPVTKGPLTYDRERDELVSRSARLAYPVRDGIPVLLETEARPLTDAELEA
What are the official names of this protein?
UPF0434 protein Aave_2563.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: KHSE_STRPN
Sequence: MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQIGKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLGQLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIPNYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYRQDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHDLRVDTQGVRVEAK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG059_VACCW
Sequence: MVIGLVIFVSVAAAIVGVLSNVLDMLMYVEENNEEDARIKEEQELLLLY
What is the function of this protein?
May play a role in cell adhesion and is important for virus virulence in vivo, although it is not required for the virus life cycle in cell cultures.
What are the official names of this protein?
Protein OPG059.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG058 family.
Protein: ARL4A_RAT
Sequence: MGNGLSDQTSILSSLPSFQSFHIVILGLDCAGKTTVLYRLQFNEFVNTVPTKGFNTEKIKVTLGNSKTVTFHFWDVGGQEKLRPLWKSYTRCTDGIVFVVDSVDVERMEEAKTELHKITRISENQGVPVLIVANKQDLRNSLSLSEIEKLLAMGELSSSTPWHLQPTCAIIGDGLKEGLEKLHDMIIKRRKMLRQQKKKR
What is the function of this protein?
Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).  GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit.  Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 4A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is dependent by nucleotide binding.
Protein: AROQ_BARHE
Sequence: MSMIITILNGPNLNFLGKREPEIYGTETLKDIEQFCKECATRLGVRIHFYQSNYEGQLVEWIQEAIGVSAGLIINPAAYSHTSVAILDALKMFTGTKVEVHLSHIYHREAFRHHSYTSAAVDAVIAGCGGDGYWLALEYIVKRFNRNK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: ATPG_FUSBL
Sequence: MPSLKDLKNRIGSVKNTRKITKAMQMVAAAKLRRAQDSAEAARPYAERMGAVIASLASGQGAGAPRLLAGNGRDQIHLLVVMTSERGLCGGFNSTIVRLARQRANELVAQGKTVKILTVGKKGREQLKRDWASAFVGHVDLSDVRRLGYSNAQGIAREVLAAFEAGEADVVTIFYNRFQSVISQVPTAQQVIPAKFEAAETNALYDYEPSEEAILADLLPRGVATQIFTALLENAASEQGARMSAMDNATRNAGDMINKLTIQYNRSRQAAITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYC_TRIEI
Sequence: MALKLYNSLTRQEETFEPLEPNIIKMYVCGVTVYDYCHLGHARSYIAWDTMRRYLIWQGYQVRYVQNFTDIDDKILKRARETGSSMDSVAKRFTEAYFEDMKRLNVLEADEYPRATQNIDRIQNLIHDLEKKGFAYSSGGDVYYQVREFSQYGKLSGRRLEEMQAGASGRVDSEDLETAKKKDPFDFALWKAAKTGEPAWDSPWGKGRPGWHIECSAMVQDCLGETIDIHAGGADLIFPHHENEIAQSEASTGKILARYWLHNGFVTINGEKMSKSLGNFTTIRDLLDQPVDPMALRMFVLTAQYRKPIDFTEEAIASAKNGWNTIKEGILFPYQYGPKLGWEMPAKNLSDQTLLLTSYLEKFQKAMDDDINTPAALAILFELAKDLRREGNVLIHEGKTETSLEELKKQWVTLVSLSQVLGLEVKIEEQVSNISEGLSNIEIESLIQQRLEAKKAKNYSEADRIRNELQSQGIKLIDKSGGLTNWHRN
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABV_PSEA7
Sequence: MIIKPRVRGFICVTTHPAGCEANVKQQIDYVEAKGPVVNGPKKVLVIGSSTGYGLAARITAAFGSGADTLGVFFERPGSESKPGTAGWYNSAAFEKFAHEKGLYARSINGDAFSDEVKRLTIETIKRDLGKVDLVVYSLAAPRRTHPKTGEVFSSTLKPIGKSVSFRGLDTDKEVIKDVVLEAASDQEVADTVAVMGGEDWQMWIDALLEADVLADGAKTTAFTYLGEKITHDIYWNGSIGAAKKDLDQKVLGIRDRLAPLGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEQGTHEGCIEQVDGLYRESLYGAEPRLDEEGRLRADYKELQPEVQSRVEELWDKVTNENLYELTDFAGYKSEFLNLFGFEVAGVDYEQDVDPDVQIANLIQA
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: MCM2_XENTR
Sequence: MADSSESFNIATSPRTGSRRDALTSSPGRDLPPFEDESEGMFGDEVPREEEEDGEELIGDAMERDYRAISELDRYEAEGLDDEDDVEDLTASQRDAAEQAMRMRDREMGHELGRMRRGLLYDSDEEDEDRPARKRRMAERAAEGAPEEDEEMIESIENLEDMKGHTVREWVSMAATRLEIYHRFKNFLRTHVDEHGHNVFKEKISDMCKENKESLVVNYEDLAAREHVLAYFLPEAPAEMLKIFDEAAKEVVLVMYPKYDRIAREIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTCCTGVLPQLSMVKYNCNKCNFILGPFFQSQNQEVKPGSCPECQSLGPFEINMEETVYQNYQRITIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTGTYHNNYDGSLNTANGFPVFATVILANHITKKDDKVAVGELTDEDVKAIVALSKDERIGERIFASIAPSIYGHEDIKRGLALALFGGEAKNPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQGASAVGLTAYVQRHPVTKEWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTIIAASNPIGGRYDPSLTFSENVDLTEPIVSRFDILCVVRDTVDPVQDEMLARFVVGSHIKHHPSSKDIANGEEFALPNTFGVEPLPQEVLKKYIMYSKEKIHPKLNQMDQDKVAKMYSDLRKESMATGSIPITVRHIESMIRMAEAHARMHLRDYVVEDDVNMAIRVMLESFIDTQKFSVMRSMRKTFARYLAFRRDNNELLLFVLKQLVAEQTSYQRNRYGAQQDTIEVPEKDLVDKARQINIHNLSAFYDSDLFKMNRFTHDVKKKMIIQQF
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.  Required for the entry in S phase and for cell division.
What are the official names of this protein?
DNA replication licensing factor mcm2, Minichromosome maintenance protein 2.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses.
Protein: ARP3_ARATH
Sequence: MDPTSRPAIVIDNGTGYTKMGFAGNVEPCFILPTVVAVNESFLNQSKSSSKATWQTQHNAGVAADLDFYIGDEALAKSRSSSTHNLHYPIEHGQVEDWDAMERYWQQCIFNYLRCDPEDHYFLLTESPLTPPESREYTGEILFETFNVPGLYIAVNSVLALAAGYTTSKCEMTGVVVDVGDGATHVVPVAEGYVIGSCIKSIPIAGKDVTLFIQQLMRERGENIPPEDSFDVARKVKEMYCYTCSDIVKEFNKHDKEPAKYIKQWKGVKPKTGAPYTCDVGYERFLGPEVFFNPEIYSNDFTTTLPAVIDKCIQSAPIDTRRALYKNIVLSGGSTMFKDFGRRLQRDLKKIVDARVLANNARTGGEITSQPVEVNVVSHPVQRFAVWFGGSVLSSTPEFFASCRTKEEYEEYGASICRTNPVFKGMY
What is the function of this protein?
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament (By similarity).  Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.  Involved in the control of cell morphogenesis in leaf epidermal pavement cells, root hairs, hypocotyls epidermal cells and trichomes, especially during rapid cell expansion.  Regulates the directionality of cell expansion by regulating the actin organization, and thus the microtubules distribution and the fusion of small vacuoles.
What are the official names of this protein?
Actin-related protein 3, Protein DISTORTED TRICHOMES 1.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: Y207_RICPR
Sequence: MFRNIQLVAINYSCYFVTHTHYFNLLFLLLLNVSKRASQRFHSYILCYLVCVVSAFSYNDINFIYLL
What are the official names of this protein?
Uncharacterized protein RP207.
Protein: METRE_DESRM
Sequence: MSILFSPAQIGTLQLRNRIIMTPMHLGYTPNGEVTDQLIEFYRVRARGGAGLIVVGGCGIDRIGNAYGMTQLDDDRFIPGLRRLADAVQAEGAKIVAQLYQAGRYAHSALTGQPAVAPSPIPSKLTGETPVELTEEKIAEIVASFAKAAKRAKTAGFDGVEIIASAGYLISQFLSPLTNKRTDRYGGDLQARMTFGLEVVAAVREAVGSDYPIIVRVAGNDFMPGSHTNTEAQVFCQAMEKSGVNAINVTGGWHETQVPQITMNVPPGAYAYLAYGIKQAVSIPVIACNRINTPDLAEAILQEGKADFIGMARSLMADPELPNKAMSGHPEQIRPCIGCNQGCLDHVFRMKPVSCLVNAEAGREAELSLTPTSQPGKILVIGAGAAGLEFARVAALRGHKVTIWEESDQAGGQLILAAAPPGRKDFLHLRTYLVNACRDLGVEIQYHTKATPENILSAVQEGKFNRVVIATGAHPITPPIPIEEGVKVIQAWDVLAGRSKAGQNIIIVGGGAVGVETALLLAESGTLDNETLRFLMLQQAETEKELYRLLIQGTKKITVLEMANGIGRDIGPSTRWSMLADLKRHQVNCLDETTVLEIRREGVLVKNAGTQKILPADTVILAVGSRSQNELYQALQGKVEYLSIIGDAIKPRKVMDAIHQAYNEAIKY
What is the function of this protein?
Metal reductase able to reduce Fe(III)-chelates to Fe(II)-chelates, as well as soluble Cr(VI) and U(VI), using NADH as electron donor.  Cannot use NADPH as an electron donor.  Is unable to reduce riboflavin and FMN with NADH as electron donor.  May have an in vivo role in metal reduction in D. reducens, which is an organism capable of reducing contaminant heavy metals and radionuclides.
What are the official names of this protein?
Metal reductase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_STAHJ
Sequence: MFNSSSLNVYFICGTQDVPEGKDIREILKQALEAGITLFQFREKGPTSLDGVEKEHLAIDLLKLCHDYQVPFIVNDDVDLAEKINADGIHVGQDDENVKSFAERFKDKIIGLSIGNEKEYYHSDLEHVDYIGVGPMFATISKNDANAPVGPSMIATLKNINPSLPMVAIGGITEDNIEPIAQNGADGVSVISAIARSHNIDKTVTKMKSYFK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: NU4LM_CHICK
Sequence: MSPLHFSFYSAFTFSSLGLAFHRTHLISALLCLESMMLSMFIPLSIWPVENQTPSFALVPILMLAFSACEAGTGLAMLVASARTHGSDHLHNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: I2BP2_XENLA
Sequence: MSSATVAASRRQSCYLCDLPRMPWAMIWDFTEPVCRGCVNYEGADRIEFVIETARHLKRAHGFQEGRSPGPSPSSSSSSSSSSSVKPQLSAKEMAQIGHTMGGPEGVTRTSQQPPPPQCLDRYSLERPPPPRLGSEYGLGRQVNGILLPNGFPKPEEPPELNRQSPNPRRTSTVPQSLGALMNGTPMGSARATIGLSGASLVAAAAATTSADLSGKRPGSVSSSEHDGKEKHRADSYSELGENHKSRAEEWISKPKTVRDTLMAMQHSHSPFDSKFKKDTGPGRVLSFEANNPVSKSGARGGRKRKTSPEPEGEGGSVKINGEGQPWLPATESLKISTMASPSFISPPSTVSPHSNRTTPPEAAQNGQSPMAALILVADNAGGNHASKDANQVHSTTRRNSSSPPSPSSMNQRRMAPRDVPSQLPSGGTSSHAGMEQGLPQSIPDSSIPNSIPLCCTLCHERLEDTHFVQCPSVPSHKFCFPCSRQSIKQQGSSGEVYCPSGEKCPLVGSNVPWAFMQGEIATILAGDVKVKKERDS
What is the function of this protein?
Acts as a transcriptional repressor.
What are the official names of this protein?
Interferon regulatory factor 2-binding protein 2, IRF-2-binding protein 2, IRF-2BP2.
What is the protein family that this protein belongs to?
Belongs to the IRF2BP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HMGCL_CHICK
Sequence: AFPQRVKVVEVGPRDGLQNEKSVVPTPVKIRLIDMLSETGLPVIEATSFVSPRWVPQMADHAEVMQGINKLPGVSYPVLTPNLKGFQAAVAAGAKEVSIFGAASELFTKKNINCSIEESLERFSEVMNAARAASIPVRGYVSCVLGCPYEGNISAAKVAEVSKKMYSMGCYEISLGDRIGIGTPGSMKEMLAAVMKEVPVGALAVHCHDTYGQALANILVALQMGVSVVDASVAGLGGCPYAQGASGNVATEDLVYMLNGLGIHTGVDLQKLMDTGTFICNALNRRTNSKVSQAACRL
What is the function of this protein?
Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis.  Terminal step in leucine catabolism.  Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.
What are the official names of this protein?
Hydroxymethylglutaryl-CoA lyase, mitochondrial, HL, HMG-CoA lyase, 3-hydroxy-3-methylglutarate-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA lyase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Peroxisome. Note=Unprocessed form is peroxisomal.
Protein: RBL_STEHA
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYQTLDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIDPVPGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDYTEIDANRGIYFTQSWVSTPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNTIIREASKWSPELAAACEVWKEIKFEFPAVDTLDKDKKKG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RECF_BACHK
Sequence: MFISEIQLKNYRNYEKLELSFEDKVNVIIGENAQGKTNLMEAIYVLAMAKSHRTSNDRELIRWDEDFGQIKGKLQKRNSSLSLELNISKKGKKAKLNQLEQQKLSQYIGVMNVVMFAPEDLNLVKGSPQVRRRFLDMELGQIAPVYLYELSQYQKVLTQRNHLLKKMQGNSKNEETMLDVFTLQLIEHGTKILQKRFEFLHLLQEWAAPIHRGISRGLEELEIVYKPSVDVSESMDLSKIKEVYYESFQSVKQREIFRGTTLIGPHRDDLQFFVNSKNVQVFGSQGQQRTTALSLKLAEIELIYSEVKEYPILLLDDVLSELDDYRQSHLLNTIQGKVQTFVTTTSVDGIEHETLKEAKTIHVTNGTVDCEIDRA
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_MYCGI
Sequence: MAELIISASDIEGAIEDYVSSFTADSEREEIGTVIDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSVGAVILGEFEKIEEGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDGQGDIESDTRRALELQAPSVVQRQGVSEPLQTGIKAIDSQTPIGRGQRQLIIGDRKTGKTAVAVDTILNQRKAWETGDPKQQVRCVYVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAPYTGSAIGQHWMYDGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLSDELGGGSMTGLPIIETKANDISAFIPTNVISITDGQCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLELSQYRELESFAAFASDLDAASKAQLDRGARLVELLKQPQYTPYSVEDQVVAIFLGTKGHLDSVPVEDVSRFEQEVLEHVKASHDDILQEIRETKKLSESTEEKLTNVINDFKKGFSASDGSSVVVNEADAEAMDEADVEKESVKVRKPAPKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CGR1_ASHGO
Sequence: MAVKNLEKGINVSGRVWKSEKDAFRATSKVIKNKKLTSWELKREQRQLDQQFKERMNALKNEKEEERQQRIKALRERREKKEEKERYERLAARMHAKKVERMRRREKRNKALKER
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein CGR1.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RF3_IDILO
Sequence: MSESSLQNEVAKRRTFAIISHPDAGKTTITEKVLLHGQQIQKAGTIKGKKSGQHAKSDWMQMEQERGISVTTSVMQFPYHNALVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDGAKGVEDRTIKLMEVTRLRDTPIITFMNKLDRDIRDPLELLDEVEDVLKIMCAPITWPIGSGKNFKGVYHLLKDETILYKTGQGHRIQEETIIKGLDNPELDEKLGVWADELREQIELVNGASNPFDKELFLAGELTPVFFGTALGNFGVDHMLDGLVDWAPKPQGRETDQQEGVSATSEDFSGFIFKIQANMDPRHRDRVAFMRIVSGKYEKGMKMRQVRTGKDVRISDALTFLAGDRSHVEEAYPGDIIGLHNHGTIQIGDTFTAGEDFKFSGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPLISNDLIVGAVGVLQFDVVVHRLRTEYKVDAMYENINVATARWVSSKDEKKLDEFRRRAEANLALDGGDNLTYIAPTMVNLSLAEERYPDIEFTHTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_AROAE
Sequence: MTARILDGNALSARVRGELAERAAALADGGVQPCLAVILVGVNPASAVYVRNKVAACEKAGIRSLRFDFAADVDAAEVMAKIAELNADSAVHGVLVQLPLPKQFNEAEVLEAIRVEKDVDGFHAENVGRLSQGQEAFLPCTPHGVMKMLEAGGVPVQGAEAVVIGRSNIVGKPMAMLLTNAGATVTVTHSKTRDLAFHTRRADILVAAIGKPRFVTGDMIKPGAVVIDVGINRLTEGPDAGKLCGDVDFESAKEVASLITPVPGGVGPMTITMLLANTVESAERVARSKG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: Y053_RICCN
Sequence: MKASLTCVGEYYNNVEQTELYLKAVASLRQTALYTSKPKDTDILLGKAFYKAGKLSEAGTVLNKYIYILSRE
What are the official names of this protein?
Uncharacterized protein RC0053.