PharMolix/UniProtQA huggingface dataset:
Protein: BRG2_ARATH
Sequence: MAVDAHHLFLSPPQLFSNRELTMNNNTMEPTSGGFCNNNQTGYGVVSPFSVPNHTSTTTTATPPLLHVYGGSDTIPTTAGYYADGATNLDCEFFPLPTRKRSRDSSRSNYHHLLLQNPRSSSCVNAATTTTTTTLFSFLGQDIDISSHMNQQQHEIDRFVSLHLYQMERVKYEIEEKRKRQARTIMEAIEQGLVKRLRVKEEERERIGKVNHALEERVKSLSIENQIWRDLAQTNEATANHLRTNLEHVLAQVKDVSRGAGLEKNMNEEDDAESCCGSSCGGGGEETVRRRVGLEREAQDKAERRRRRMCRNCGEEESCVLLLPCRHLCLCGVCGSSVHTCPICTSPKNASVHVNMSS
What is the function of this protein?
Probable E3 ubiquitin-protein ligase.  Has no effect on the stability of the DELLA proteins.
What are the official names of this protein?
Probable BOI-related E3 ubiquitin-protein ligase 2, RING-type E3 ubiquitin transferase BRG2.
Protein: PSBH_HUPLU
Sequence: MATQISDISRRTKVKSTGLGNALKPLNSEYGKVAPGWGTTPIMGVAMASFAVFSVIILELYNSSVSLDGIPVSW
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FDHD_ALKCK
Sequence: MEKNIQTSRQIWRFQAGEPVRIDDPIAREQPVTLKINGEEFATLVCTPTYLQEMAIGFLVSEGLIQAYEEVKTIWIDDRQGFIHIELVRPIDRLHQHLQTKRYMGSCCGMSRQGFVFASDAKTAKKVQTRDVKLNAGDCFRLMAELQENARTFQQTGGVHNAALATKDGLLLMREDVGRHNALDKLYGHCLQNGLSLHGKLVVFSGRLSAEIILKVAKIGCELVLSKSAPTDRALQIAEELDITTVGFIRNRSMNVYTVPERIELKS
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3A_ASPFU
Sequence: MAVGKNKRLSKGKKGVKKRTVDPFSRKDEYSVKAPSTFQIRDVGKTLVNRTSGLKNANDSLKGRIFEVSLADLQNDEDHAFRKVKLRVDEVQGKNCLTNFHGLDFTTDKLRSLVRKWQSLIEANVTVKTTDDYLLRLFAIAFTKRRPNQIKKTTYARSSQIRAIRKKMIEIMQREAASCSLAQLTHKLIPEVIGREIEKATQGIYPLQNVHIRKVKLLKAPKFDLGALLNLHGESTTDDKGHKVEREFKEQVLESV
What are the official names of this protein?
40S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_CAUVN
Sequence: MTMKGGVASQDFSAAIATACEPAANVWSKVCVALKRELGDAAFGSWIAPAMLREAATGDVVLVTSTGIARDWIRRSAWRRIGELWAAHDATGRRIDLKSRLEFEAAAGAYVEATPKAVAAEPIEIVLPVSTDAPTVVAPSAKSPRTQGLQERFTFETFVPGPANEFAHAVARRIANWADGHFNPVLFHGPYGFGKTHLLNALAWEAMRNAPEKRVVYLTAERFLSTFVRAVMDRQTAAFKEELRAADLLIIDDVHFIAGKQSTQEELFHTLTALVGEGGRVVFSADRPPSAMTEMDAHLRSHLSAGLVCGLEPADRNLRLGILERKIQTLGAAHGFEPSIRPEVMQFLADRFTDSVRELEGALNTLSARAGEGLSRMTLDEVQAILRPHLRSGEKRITIDDIQKATAEHYGMKQADLLSERRNRAVARPRQAAMWLAKQLTTRSLPDIGRRFGGRDHTTVLHAVRRIEALRAEDSALSHDLETLTRKLRG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids (By similarity).
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL371_ORYSJ
Sequence: MTKRTKKAGIVGKYGTRYGASLRKQIKKMEVSQHSKYFCEFCGKFAVKRKAVGIWGCKDCGKVKAGGAYTMNTASAVTVRSTIRRLREQTEA
What are the official names of this protein?
60S ribosomal protein L37a-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: SL9C2_HUMAN
Sequence: MSSYFWAQNESNRPDLLCGQPADYLVEEKHFTTLVCFIVVLGGLLKMCLKNCEVIVLTILSLSGFVIGHMAYNSVEVHQIVYPLLRTSSFSLYSYFSPLIIFMVALDVEFYTLKKMFWQVLLTGLISFSTASIIIGYVVIKFNKDSWDLQSCLLFSITLGIIDPLRSVNSLKTIGISKIYIDLIRGESLIICSIASIFFGNFRGNRIHFSIFRDLHVGIELSYDILGSIIFGYWCAKIIQCILADVFSNMLTNIILCFSMVYMTFYIVEFLGMSGTLALAAVGLNLDSLTFKPKIELVITKFLRIFSSVYEHLIYAFFGIVIGCGELSHYEFHTIPFIFILFTTVNLVRLLTILLVSPILMHSNYEYNWRWGVVITWSGIKGVFNLLWAPDVYNLAERKVEVPQMFILYVQVISLLTMGINSYVMTQSARKLDLCVLSLPRQMILQNATQHIQEIVQNTITLFKTEKILTNVNWTLVEDKTRIEYIPFSHVSHNDMKTESTTDEALMEEARLHVAAIQMSSFEKQRNNGILEIEAARILIGAAKCYYSIQGKFMSIYDVSTYMRTRSWLIKFKNVLTFLEYCIEKIHFIPPESNTFLTFIFHIVFSEEFEYTGQIINLIYIYPMIIHLWPMARGLNVSALISINYYFMFLYVLESTLKIIILKRKYFQQCWNTLEFFILVIGIIDIFCVYFVKLRPDNLALIQLTVIMGYLRIIRFLPLFKIIVPILIRIADVQIKKRLSLMYSITKGYIKSQEDAKLLIKQIAVCESIYQKLCEILETNKQDAVKELVLMEHEGRDVVIALKTKQAIRNVIAKALKNLTFLCSRGIIDKHEVIEINKVLLKKLKALNNFPKAIPPPTPDIYLHNIIWLEGKDVLIDFFKERAKLACFDSGDTICKGGEMPQGIYLIISGMAILHSLSPTFGIESNQRCDRGSRDMFTEFCTTGDIIGELSCLLKREIEYTVICETSLQACFISLEDLYEGFDAFWPSLEYKIWLKLALSTAYQYFESSLIDEDLRFQNCVMFNQAYVETLSSYSDMIIDNMTMKFVIIVYGSVIDTKTEEPYFAPCIIPTTCEQVQGTSDLSKLLIIQASELTQRNSNTNVMASVNTVFEQPGKNINGRQKMS
What is the function of this protein?
Involved in pH regulation.
What are the official names of this protein?
Sodium/hydrogen exchanger 11, Na(+)/H(+) exchanger 11, NHE-11, Solute carrier family 9 member 11, Solute carrier family 9 member C2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PLSX_SHEB5
Sequence: MTNLTLALDAMGGDHGPHVTVPAALRALQLHSFLKIILVGDKTEIDVYLRQAEANLLSRIEIIHTDEVVSMSDRPVHALRTRKNSSMRLAIELVRDDRAQACVSAGNTGALMAMAKVLLKTLPGVDRPALVSCLPAVTQKPVYLLDLGANISCDSETLFQFAVMGSVLCEAVDKKSRPKVALLNVGIEEIKGNDQVQQAAQLLQHTDQINYTGFIEGDEIYSGNVDVIVCDGFVGNITLKTSEGIAKLLVHQLKRGLTQGLFVRFLAKLIAPRIQAVLSQMNPDHYNGASLIGLRGIVVKSHGNADETAYLQAISLAVTEAQRRLPEMIKDRLESILLDINN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RL9_SACD2
Sequence: MEVILLEKVGKLGTVGDVVDVKAGFGRNYLLPSGKAITATKASIADFETRRAELEAAAAEKKTSAEGRAKLIDNLGAITIGANAGDEGKLFGSVGARDIANAITAAGVNVTKAEVKLPEGTLREVGEYEIDLQLHVDVTHVVKVVIVADANA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: LUXS_ECO81
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARNILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: PSP2_YEAST
Sequence: MGTNNTSNNNGTTKKMSLEEFLGNDTLGESVWDEEDINLDAISNTTNIDILKQTKAGEHQRDGHQQHPHGGHGPMNRSRFSNAGPFGGGSMGDFANHHHPLQHQQGPPYIVKFSDLPPRFSNFDIEDLFQAKFTKFIKFKLFWEINKNPSISTLKSGSIFDQNFKRDSKVAFVELYTSRDMDKILNYWTTPLKEIYHITTAPAEFEDFKDYSTKVKLLTDPKDDAGKPFITKTQRSKSNPFGSAKPVDTQSKILDIEEKMENLHVEDTTTLRASLIPSSDSMATTATGSKITILKKQTPTEEESHSATPTPKPLSYSEVVERSVVNETSKKGTPLSKLDSPALELQSKPDKSDEFKGGDEQGFEKGGDDKAQLDVSNDKDKGSETDVDKQFTFKNVEREHSMSRTKYNGNHNNNNGNFRGSNRYRGGPNGSSYKGGHNNRGNRGGYRGGSSYNNNNNNTNDNNNNNNNSSSNNNNGSRYHDRQNNEEGLTSDSSLDASGNKKNDFTNSTSNTQQYSIFKPASGFLGQGNNDSIRNNGRGNYNSSGMNGGSRGRGFGRGRGFGRGAYNNRGSRGGRGSSGNYSNYNNRTTDMPL
What is the function of this protein?
DNA polymerase alpha mutation suppressor.  Suppressor of group II intron splicing defects of a mutation in MRS2.  May play a role in mitochondrial mRNA splicing.
What are the official names of this protein?
Protein PSP2, Mitochondrial regulator of splicing 15, Polymerase suppressor protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Cytoplasm, Stress granule.
Protein: UPE26_UPEMJ
Sequence: GILDIAKKLVGGIRNVLGI
What are the official names of this protein?
Uperin-2.6.
What are the subcellular locations of this protein?
Secreted.
Protein: C12B1_DROAC
Sequence: MWKFAIHSQQPFCWQQLCNRRHLYVGNVQQQTHLELLDAAPTRSDDEWLQAKPYEKVPGPGTWQVLSYFLPGGKQYNTNLIQMNRRMREWYGDIYRFPGLMGKQDVIFTYNPNDFELTYRNEGVWPIRIGLESFTYYRKVHRPEVFGSIGGLVSEQGKDWAHIRNKVNPVQMRVQNVRQNLPQIDQISREFVDKLDTLRDPVTHILNDNFHEQLKMWAFESISFVALNTRMGLLSDRPDPNAARLAEHMTDFFNYSFKYDVQPSIWPYYKTPGFKKFLQTYDKITEITTAYIDEAIKRFEIEKDSGNECVLQQLLSLNKKVAVVMAMYMLMAGIDTTSSAFVTILYHLARNPHKQRQLHRERRRILPDSDEPLTPENTKNMPYLRACIKECMRITSITPGNFRIATKDLVLSGYRVPRGEGVLMGVLELSNSEKYFGQSGQFMPERWLKADTDPDVKACPAARSRNPFVYLAFGFGPRTCIGKRIAELEMETLLTRLLRRYQVSWLAEMPLQYESNIILSPHGIYVQVRAAC
What is the function of this protein?
Probably involved in steroid hormones biosynthesis.
What are the official names of this protein?
Cytochrome P450 12b1, mitochondrial, CYPXIIB1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SODM_SALTI
Sequence: MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALENLPEFADLPVEELITKLDQVPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAAIERDFGSVDNFKAEFEKAAATRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGASGFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], MnSOD.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: ECHM_PONAB
Sequence: MATLRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQIKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRTVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIIAAMAKESVNAAFEMTLAEGSKLEKKLFYSTFATNDRKEGMTAFVEKRKANFKDQ
What is the function of this protein?
Converts unsaturated trans-2-enoyl-CoA species ((2E)-enoyl-CoA) to the corresponding (3S)-3-hydroxyacyl-CoA species through addition of a water molecule to the double bond.  Catalyzes the hydration of medium- and short-chained fatty enoyl-CoA thioesters from 4 carbons long (C4) up to C16 (By similarity).  Has high substrate specificity for crotonyl-CoA ((2E)-butenoyl-CoA) and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA (3-methyl-(2E)-butenoyl-CoA) and methacrylyl-CoA ((2E)-2-methylpropenoyl-CoA).  Can bind tiglyl-CoA (2-methylcrotonoyl-CoA), but hydrates only a small amount of this substrate (By similarity).  Plays a key role in the beta-oxidation spiral of short- and medium-chain fatty acid oxidation.  At a lower rate than the hydratase reaction, catalyzes the isomerase reaction of trans-3-enoyl-CoA species (such as (3E)-hexenoyl-CoA) to trans-2-enoyl-CoA species (such as (2E)-hexenoyl-CoA), which are subsequently hydrated to 3(S)-3-hydroxyacyl-CoA species (such as (3S)-hydroxyhexanoyl-CoA) (By similarity).
What are the official names of this protein?
Enoyl-CoA hydratase, mitochondrial, mECH, mECH1, Enoyl-CoA hydratase 1, ECHS1, Short-chain enoyl-CoA hydratase, SCEH.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RLR64_PLAVT
Sequence: MMSPPMTTTLMFILNYAIISFHGQPSGISWGNHIETAEAAAILAMANRELRSRELLLWTSGSTHLLLQPILPLPLCLPFPLVPASIFKKMMLPLSAFSFWM
What is the function of this protein?
Effector that acts as a broad suppressor of cell death to interrupt plant immunity.  Inhibits cell death induced by cell death-inducing proteins, including the PAMP elicitor INF1 from P. infestans.
What are the official names of this protein?
Secreted RxLR effector protein 64.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Membrane; Single-pass membrane protein.
Protein: RIBD1_BUCAI
Sequence: MNDIFYMKRAIELSKLGEFTTAPNPNVGCVIVKNNIIVGEGWHEQAGKNHAEINALIMAGEKAQGGTAYVTLEPCNHFGKTPPCCNALIKSGINRVVISNIDPNPKISGNGILYLKKHGICVKTGLLSKESKQYNKGFFKRMKTGFP
What are the official names of this protein?
Diaminohydroxyphosphoribosylamino-pyrimidine deaminase, DRAP deaminase, Riboflavin-specific deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: RL28_GLOC7
Sequence: MARHCELTGKKANNAFSISHSHRRTKRLQHANLQWKRIWWEEGKRWVKLRLSTKAIKTLEKKGLASMAKEAGINLNQY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RF1ML_BOVIN
Sequence: MRPRLVWNVFRGFWARRGVVPACRHLSCSNLPLEELFARGGALRTFLERQVGAEAQFQVRRPELVAVAKLLSDKEQELQETQHLLHDENEDLRKLAENEITSCEKEIAQLKHQIILLLVPSEETDKNDLILEVTAGVGGQEAMLFTSEIFDMYQQYAAFKRWHFETLEYFPSEIGGLRHASASIGGSEAYKHMKFEGGVHRVQRVPKTEKQGRIHTSTMTVAILPQPTEINLVINPKDLRIDTKRASGAGGQHVNTTDSAVRIVHLPTGIVSECQQERSQLKNKEMAMKKLRAKLYSLQLEEETSKRYNARKIQIGTKGRSEKIRTYNFPQNRVTDHRINKSLHDLETFMQGEYLLDELVQSLKDYANYESLVEIIAKEV
What is the function of this protein?
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
What are the official names of this protein?
Peptide chain release factor 1-like, mitochondrial, Mitochondrial translational release factor 1-like.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS5_THEKO
Sequence: MSDPREIAQRVLEEWEPKTKLGRLVKEGQITDIHEIFRKGYQIKEPEIVDVLLPEVNLRENQEVLDIALTVRMTDSGRRIRFRVLAAVGNRDGYVGLGIGHGREVGIAIRKAINYAKMNIIEIKRGCGSWECRCRRPHSIPFAVEGKEGSVRVKLMPGPRGLGLVIGDVGKKILTLAGVQDVWSQTLGETRTTVNFAKAVFNALYNTNRVAIKPEDIERYGIVVGRAMPTTFEVE
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: IF2_BACAH
Sequence: MSKIRVHEYAKKHNISSKDLMTKLKEMNIEVSNHMTMLDDEVVNKLDNEYQAEKPSVADEFEVEEKVVRSKKNSNKKKKKGKGNEDKRQENFAGRQQTQTVETPDKITFSGSLTVGDLAKKLSKEPSEIIKKLFMLGIMATINQDLDKDTIELIANDYGIEVEEEVIVSETEFETFIDEQDDEENLKERPAVVTIMGHVDHGKTTLLDSIRNSKVTAGEAGGITQHIGAYQVEVNDKKITFLDTPGHAAFTTMRARGAQVTDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKMDKPAANPDRVMQELTEYELVPEAWGGDTIFVPISAIQGEGIDNLLEMILLVSEVEEYKANPNRYATGTVIEAQLDKGKGTIATLLVQNGTLRVGDPIVVGTSFGRVRAMVSDIGRRVKVAGPSTPVEITGLNEVPQAGDRFMAFADEKKARQIGESRAQEALLAQRGEKSKLSLEDLFQQIQEGDVKEINLIVKADVQGSVEAMAASLRKIDVEGVKVKIIHTGVGAITESDIILASASNAIVIGFNVRPDVNAKRTAELENVDIRLHRIIYKVIEEIEAAMQGMLDPEFEEKVIGQAEVRQTFKVTKVGTIAGCYVTDGKITRDSGVRIIRDGVVIFEGQLDTLKRFKDDVKEVAQNYECGITIERYNDLKEGDIIEAYIMEEVKR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_OENOB
Sequence: MKKTMFDKIWHQHVITGEPGEPQLIYVDLQLLHEVTSPQAFEGLREKNRQVRRPDRNFATMDHNVPTVDIFNIKDLISKKQIETLAKNTKDFGIRLAGMGSKDQGIVHVIGPQLGLTQPGMVIVCGDSHTATHGAFGSIAFGIGTSEVEHVLATQTIWQTKPKTIGIHVHGKLSIGVYAKDIIMGIIAREGVSFGTGYAVEFYGDTIRNMNMEERMTLCNMVIEGGAKMGSIQPDQTTFDYIADRKYAPGNMEKAVSYWKQFYTDSPDAFDKVIDFSVNELAPFVSWGTNPGMAVPIDQPFPKIKNEEDKKAYEYVGLKAGEKANQIPIKFVFFGSCTNGRLSDLIIAAKVLKNKHIKNGITALVVPGSRKIKEKAEKIGLDKIFKEAGCEWREPGCSACLGMNPDRVPAGIHCASTSNRNFAGRQGAGSRTHLASPAMVAAAAIHGRFIDIRKEII
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SYDP_ALTMD
Sequence: MALTISAQLDKFVSSYVEHAKGEGLKIAFDSEWPSPCYEETAKDGELVEWAPKRQSPPLSFNNVEDALSLKLHADYCCYFTTYYSDNLKAKAPQGDCELLQVFNREDFERLQQNLIGHLLMKQRLNQAPTLFFGLTDEEDFILTVINETGEVALEQVGQAPTQILANSLAEFIEQLSPLNA
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: M2_I66A1
Sequence: MSLLTEVETPTRNGWECKCSDSSDPLVIAASIIGILHLILWILDRLFFKCIYRRIKYGLKRGPSTEGVPESMREEYRQEQQSAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: ARAB_HALH5
Sequence: MTTKYTIGVDYGTESGRAVLIDLSNGQELADHVTPYRHGVIDQYLPNTNIKLGHEWALQHPLDYVEVLTTSVPAVMKESGVDADDVIGIGVDFTACTMLPVDEEGQPLCLLAQYKDNPHSWVKLWKHHAAQDKANAINEMAEKRGEAFLPRYGGKISSEWMIAKVWQILDEAEDVYNRTDQFLEATDWIVSQMTGKIVKNSCTAGYKAIWHKREGYPSNEFFKALDPRLEHLTTTKLRGDIVPLGERAGGLLPEMAEKMGLNPGIAVAVGNVDAHAAVPAVGVTTPGKLVMAMGTSICHMLLGEKEQEVEGMCGVVEDGIIPGYLGYEAGQSAVGDIFAWFVKHGVSAATFDEAQEKGVNVHALLEEKASQLRPGESGLLALDWWNGNRSILVDTELSGMLLGYTLQTKPEEIYRALLEATAFGTRAIVDAFHGRGVEVHELYACGGLPQKNHLLMQIFADVTNREIKVAASKQTPALGAAMFASVAAGSEVGGYDSIEEAAKKMGRVKDETFKPIPEHVAIYEKLYQEYVTLHDYFGRGANDVMKRLKALKSIQHRPSSLLT
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: CBG95_UNIPI
Sequence: TSHGGGKAGKSKLLDVNY
What is the function of this protein?
Calcium-binding.
What are the official names of this protein?
Calcium-binding shell glycoprotein P95.
Protein: SECF_SEBTE
Sequence: MDLKLMKTRNVYFIFSTFMILFSLFSIFTKGFNLGIDFTGGNIYQMKFEKPVSKEAMDKTLKEMASKYPSLKSNKVQYSEGNTVLLRTQIADEKEKSAILEELKAEQGNYELIKADAVGAVVGNELAKNALWALALGSILILIYITIRFEWIYALSSVLALLHDVLVTIGFISFFQFEVDTPFIAAILTILGYSMNDTIVIFDRIRENDHKYGGKKPFADVIDESVNKVFIRSVYTSLTTLLALAALLIFGGSTLRTFNITLLVGIVYGTYSSIWLASPLVYLLRRFKKPPKQEKNGKKDRSMEKVVV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecF.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPP5_ARTBE
Sequence: MAAAKWLIASLAFASSGLAFTPEDFISAPRRGEAIPDPKGELAVFHVSKYNFDKKDRPSGWNLLNLKNGDISVLTTDSDVSEITWLGDGTKVVYVNGTDSVEGGVGIWISDAKNFGNAYKAGSVNGAFSGLKLAKAGDKINFVGYGQSTTKGDLYNEAAAKEAVSSARIYDGLFVRHWDTYVGTQFNAVFSGSLTKNGDKYSFDGKLKNLVQPVKYAESPYPPFGGSGDYDLSSDGKTVAFMSKAPELPKANLTTSYIFLVPHDGSRVAEPINKRNGPRTPQGIEGASSSPVFSPDGKRIAYLQMATKNYESDRRVIHIAEVGSNKPVQRIASSWDRSPEAVKWSSDGRTLYVTAEDHATGKLFTLPADARDNHKPSVVKHDGSVSSFYFIGSSKSVLISGNSLWSNALYQVATPGRPNRKLFYANEHDPELKGLGPKDIEPLWVDGARTKIHSWIVKPTGFDKNKVYPLAFLIHGGPQGSWGDSWSTRWNPRVWADQGYVVVAPNPTGSTGFGQKLTDDITNDWGGAPYKDLVKIWEHVRDHIKYIDTDNGIAAGASFGGFMVNWIQGQDLGRKFKALVSHDGTFVGSSKIGTDELFFIEHDFNGTFFEARQNYDRWDCSKPELVAKWSTPQLVIHNDFDFRLSVAEGVGLFNVLQEKGIPSRFLNFPDETHWVTKPENSLVWHQQVLGWINKWSGINKSNPKSIKLSDCPIEVIDHEAHSYFDY
What are the official names of this protein?
Dipeptidyl-peptidase 5, Dipeptidyl-peptidase V, DPP V, DppV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Secreted.