PharMolix/UniProtQA huggingface dataset:
Protein: PNP_AERHH
Sequence: MNPIVKSFQYGQHTVTLETGVMARQATAAVMVSMDDTCVFVTVVGKKEADHGRDFFPLTVNYQERTYAAGRIPGGFFRREGRPSEGETLISRLIDRPIRPLFPEGFLNEVQVVATVMSVNPAVSPDIVAMIGASAALAISGIPFGGPIGAARVGYMNGQYVLNPTTTELPQSDLDLVVAGTANAVLMVESEAAILSEEVMLGAVVFGHEQMQAVINAINEFAADVGTKPWNWTAPAVNEALKAKVAELATAELGEAYRITEKAVRYETIGAIKARVVEQVIASGVEEDAKKIGEEFHSLESRIVRGRVVRGEPRIDGRDPEMIRALSVATGVLPRAHGSALFTRGETQAMVVATLGTERDAQNIDELTGNRADRFMLHYNFPPYCVGETGMMGSPKRREIGHGRLAKRGVAAVMPSADEFPYVVRVVSEITESNGSSSMASVCGSSLALMDAGVPIKASVAGIAMGLVKEEEGFVVLSDILGDEDHLGDMDFKVAGTTEGVTALQMDIKIEGITKEIMEIALKQARGARLHILKVMDEAIQAPRAEISDFAPRIHTIKINPEKIKDVIGKGGSVIRALTEETGTNIELDDDGTVRIAAVDGDAAKEAIRRIEAITAEIEVNRIYEGKVVRLADFGAFVNILPGKDGLVHISQITDARVQNVADYLKIGDVVKVKVLEVDRQGRVRLSIKEANAPTEAAAEPAVAAVEEPAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_NEOYE
Sequence: MKKTLSIHSVRKDLILGSRRLSNYWWATIIFIGALGFLLAGLSSYFQVDLLPFTNSTDLVFIPQGIVMTFYGSIGVFLSLFLWLTIIWNIGAGYNEFNKDKGIVKIFRLGFPGKNRKICLQFNIKEIKSIKIDIKEGLNPRREIYLCTKDKRVIPLTRVGQPLLLSEVEEQAAEIARFLDVVLEGA
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NUDB_HAEIN
Sequence: MRSDLTAFLMMQYKNNQSVLVVIYTKDTNRVLMLQRQDDPDFWQSVTGTIESDETPKKTAIRELWEEVRLDISENSTALFDCNESIEFEIFPHFRYKYAPNITHCKEHWFLCEVEKEFIPVLSEHLDFCWVSAKKAVEMTKSQNNAEAIKKYLFNLRR
What is the function of this protein?
Catalyzes the hydrolysis of dihydroneopterin triphosphate to dihydroneopterin monophosphate and pyrophosphate.  Required for efficient folate biosynthesis.  Can also hydrolyze nucleoside triphosphates with a preference for dATP.
What are the official names of this protein?
Dihydroneopterin triphosphate diphosphatase, Dihydroneopterin triphosphate pyrophosphatase, dATP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: EXT3_DROME
Sequence: MPPAYDLGHSGEAYQPLDTGSGGGNEACAPNSSSAQIRHSMGFRTSWMRQFRRYKLPMVLLMLLFLVSCLAYRILSVEQDAPPLDLHRSSPLLDAYEDFSAMRAGDLKMRIEEMVRIKSTVSVELRELESRRQKLQSDISQYNQKIEELKQELLREQTELERLKISVEQAQVAQREAVQRNTPDLALPRSLLPNTLPRKSNPITGGMAASCEMHNCFNHSRCSLTSGFPVYLYDPDEHSVQRKGYDIDGFLKTTLKQTLGYNAHIVKDPKHACIYLVLVGEALLEQDLLRNNRYAAQEAEHQQPSTPTLENDCPVDMEKLYSLPYWGGDGRNHVLLNLARRDLTSHRTNPLYRQNTMRAIVVQSAFEREQFRPGYDLIVPPILGPPGGDVWQECAEMVPARRKYLLTYQGELRPKQSSLNPLDAFILEHLADMAKGATQDQFVLQFQCVPATEQQEGDSLPDWTLCGSDSSRRQLLKDSTFSLILPPLNGRVSSTLMLARIYEALRSGAVPVILGADELRLPYAETVDWRRTALLLPKARITELHFLLRAVQDADLLLLRRQGRLIWERYLSSVQATVDTVIASLRDRLGIPPRPVPSVIAQSVFNSTFIPLKSDPPVGLDTEPEESLGPIEPPYPSPAFRRNYTILRMQAKEAWNDWLDPFYLYPQLPFDPALPSEAKFMGSHTGFRPIGKGLGGAGKEFGESLGGNYPREQFTIVMLTYEREQVLMDSLGRLYGLPYLHKVVVVWNSPKPPLDDLRWPDIGVPVAVLRAPRNSLNNRFLPFDVIETEAVLSVDDDAHLRHDEILFGFRVWREHRDRVVGFPGRYHAWDLGNPNGQWHYNSNYSCELSMVLTGAAFVHKYYLYLYTYHLPQAIRDKVDEYMNCEDIAMNFLVSHITRKPPVKVTSRWTFRCPGCPVSLSEDDTHFQERHKCINFFSRVFGYTPLLNTQYRADSILFKTRIPHDKQKCFKYI
What is the function of this protein?
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.  Plays a central role in diffusion of morphogens hedgehog (hh), wingless (wg) and Decapentaplegic (dpp) via its role in heparan sulfate proteoglycans (HSPGs) biosynthesis, HSPGs being required for movement of Hh, Dpp and wg morphogens.
What are the official names of this protein?
Exostosin-3, Protein brother of tout-velu.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Note=Localization to the Golgi may be regulated by sau (PubMed:23720043).
Protein: ITPA_AEDAE
Sequence: MTRPISFVTGNAKKLEEVRAILGPKFPRELLPVKLDLPELQGEIDDICRKKCLEAARRVKGPVLVEDTCLCFNALKGLPGPYIKWFLEKLEPEGLHKLLDGWEDKSAEAVCTFAYAPGEDAEVILFQGRTQGDIVYPRGCRDFGWDPIFQPKGYDKSYAELPKEKKNEISHRFRALNKLRDYFVAENQ
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_CORGB
Sequence: MQIVLASQSPSRRKILNSAGVEPLIHPADVDEDALLHSLNGSAPEEIVRQLALAKAQVVAPSYPGDVVIGGDSMLLIDATLQGKPHTREATIERWKQQRGNKATLITGHAIIFGDEVIVESSSTNIHFAEASDVDIERYADSGEPLECAGAFTLEALGGWFIDSIEGDPSSVIGLSLPVVRRALYRLGFNASDFWNM
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_STRT1
Sequence: MAGNRNEEMVYCSFCGKNQEEVKKIIAGNGVFICNECVALSQEIIREETAEEVLADLAETPKPKELLDILNNYVVGQDRVKRALAVAVYNHYKRINFTESREDNDVDLQKSNILMIGPTGSGKTYLAQTLARSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKAIDDESSYMKEIVAEDIQKFGLIPEFIGRLPVLATLEQLTVDDLVRILTEPRNALVKQYQTLLSYDGVELEFDQDALEAIASKAIERKTGARGLRSIIEEVMMDVMFEIPSLEDVTKVRITKEAVDGKAAPVLETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SRP54_RICBR
Sequence: MFKTLTQNLMKIFDRLVSSGLLTEEQIDAALRDIRVALLESDVALPVIKNFVAEVKQKALGQEVIKSVSPGQMIIKIIHEEMINILSSSEDEIKLNLNAKPPVNLLMVGLQGSGKTTASGKLALCLKNQNKKVLLVSLDTYRPAAQEQLEILANSVKINSLPIVKGEKPLDIVKRAMAEAKLSAYDIVIYDTAGRTQIDQEMMNEAIAIKKIVEPTETLLVIDSMTGQDAVVTASSFNEQLEISGLILSRIDGDSKGGAALSVKYITQRPIKFLSSGEKLTDLEEFDAKRIASRILDMGDIISFVEKAASIVDREQAEKTAAKLKKGKFDLNDYLQQMKSIKKIGGFGSILSMLPGSGKIMDQIDQSKLNSKIIEHQEAIILSMTPKERRNPDIINASRRKRIALGAGTTVQKVNILLKQFKQISDMMKKASNMNPKNLLRSGLGKLFS
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.  Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: RS20_METFK
Sequence: MANSAQARKRARQAVKQRAHNASLRSALRTAIKKIIKAVEAGDKTAAQSVFNENVSVIDRIADKKIIHKNKAARHKSRLSAAIKALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SURA_CUPMC
Sequence: MKRQAFSLLSRLNPWQQLLLSAVLVTLAAPAAAQLRAPGTRTQGIFTQQGSQSASQGSTVAPSQPMMGVPQPSSQPRSQLVDEVVAVVNNSVITRRELLDRADEIESQLRAAKREVPPRPDLLGEVLERLVMERVQTQAAQEAGIKVTDQEVDRAIESVAQQNKMSATELRSRVEASGMSWTKYRDELRKQVQVIRLREREVDSKVQVYDGEIDNYLAARNGGQAAASGPTEFNVAQILVRVPEDASDAQKAQLKTKAEGLLKQVQGGADFAELAKANSEAPEASQGGSLGFREIGRLPAVFANAVVDLQPGAVVPEVLESANGFHVVKLVSKRTAAAQPAASDRIAQTQVRHILIRTGPNMPEAEAKRQMATIRDRITHGVDFADAARRYSQDGSASQGGELGWVSPGELVPEFEQAMNRLRPGEISDPVVTQFGVHLIQVENRRETEVSPEKQRDFARAEVREQKLRAAYDDWVRQLRSAAYVEYRINRQR
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: IXTPA_NATTJ
Sequence: MKLVLASGNQGKLNELKALLSKQPVEIYSMSDFNNIKEAQETGKTFAENAIIKAQNVADSTGYLSLADDSGLEVDALDGAPGVYSARYAGENACDQDNNNKLLRSLKDIPYKQRTARFKCVIAIAYPDTPPVTFTGTCEGYILREPKGDRGFGYDPLFYHPDMGKTFGELYQEEKSSISHRGKALEKLVANFQDVMSLMEG
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: ARAA_ECOUT
Sequence: MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERIGSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: RBL_SILGA
Sequence: SVGFKAGVKDYKLTYYTPEYETLDTDILAAFRVSPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFLGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFTEKDRSRGIYFTQSWVSTPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNTIIREACKWSPELAAACEVWKEIKFEFQAMDTI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HRCA_LATSK
Sequence: MLTERQLMILKEIIRLFTESGQPVGSKKLMSELPMHVSSATIRNDMADLENVGLIEKTHSSSGRVPSMKGYRYYLDHLIQPAVLNPMDVATVQQSFGRHYHKIDEIVSQSANILSNLTSYTAITLGPEMAEIRLTGFRLVPLGNHQVMAIIVTSAGTVDNQVFTIPNAISGDELEKAIRVVNDHLIGLPLTVVSQKLKTEVPALLMQYMGSPGGFLNIFDDVLKQASQERLYVGGQSNLLNFSELTDVSQLKSIYNIINQSDDLAKLLELSPGEANSQVQVRLGDEMTNDLLKNYSLMTVNYDVGEHGQGLIALLGPTSMPHSRMIGLLDLFREELAKKLIDYYADFDDNQS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: GME72_PESMI
Sequence: MSSQPAADDVIGCLAAVYDWAESFDTKDWDRLRTVLAPTMRIDYTQVMGKIWESMPADDFIPLASDPKFLGNPLLKTQHFIGASKWEKTSDDEITGRHQVRVAHQRYADSGMKEVAKKGHAHGGATTWFKRVDGVWKFAGLCPDIRWSEYNYDEMFGEN
What is the function of this protein?
Dehydratase; part of the gene cluster that mediates the biosynthesis of dibenzodioxocinones such as pestalotiollide B, a novel class of inhibitors against cholesterol ester transfer protein (CEPT) (PubMed:31474098).  The biosynthesis initiates from condensation of acetate and malonate units catalyzed by the non-reducing PKS pks8/GME11356.  Pks8/GME11356 lacks a thioesterase (TE) domain, which is important to the cyclizing of the third ring of atrochrysone carboxylic acid, and the esterase GME11355 might play the role of TE and catalyzes the cyclization reaction of the C ring.  The lactamase-like protein GME11357 (or other beta-lactamases in Pestalotiopsis microspora) probably hydrolyzes the thioester bond between the ACP of pks8/GME11356 and the intermediate to release atrochrysone carboxylic acid, which is spontaneously dehydrates to form endocrocin anthrone.  Endocrocin anthrone is further converted to emodin via the endocrocin intermediate.  Emodin is then oxidized by several enzymes such as the Baeyer-Villiger oxidase GME11358, the oxidoreductase GME11367, the short chain dehydrogenase/reductase GME11373, as well as by other oxidoreductases from the cluster, to modify the A and C rings and open the B ring, and finally yield monodictyphenone.  The prenyltransferase GME11375 may catalyze the addition reaction between the C5 side chains and the carbon bone of dibenzodioxocinones.  The remaining biochemical reactions to the final product dibenzodioxocinones should be methylation catalyzed by methyltransferase GME11366 and reduction and lactonization reaction catalyzed by a series of oxidordeuctases (Probable).
What are the official names of this protein?
Dehydratase GME11372, Dibenzodioxocinones biosynthesis cluster protein GME11372.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
Protein: HIS2_STRCO
Sequence: MSKKTFEELFTELQHKAANGDPATSRTAELVDKGVHAIGKKVVEEAAEVWMAAEYEGKDAAAEEISQLLYHVQVMMVARGISLDDVYAHL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQRA_NEIMA
Sequence: MIKIKKGLNLPIAGRPEQVIYDGPVITEVALLGEEYAGMRPSMKVKEGDAVKKGQVLFEDKKNPGVVFTAPVSGKIAAIHRGEKRVLQSVVIAVEGNDEIEFERYAPEALANLSGEEVRRNLIQSGLWTALRTRPFSKIPAVDAEPFAIFVNAMDTNPLAADPVVVIKEAAEDFRRGLLVLSRLTERKIHVCKAAGADVPSENAANIETHEFGGPHPAGLSGTHIHFIEPVGANKTVWTINYQDVIAIGRLFATGRLNTERVIALGGSQVNKPRLLRTVLGAKVSQITAGELVDADNRVISGSVLNGAITQGAHDYLGRYHNQISVIEEGRSKELFGWVAPQPDKYSITRTTLGHFLKNKLFKFTTAVNGGDRAMVPIGTYERVMPLDILPTLLLRDLIVGDTDSAQALGCLELDEEDLALCSFVCPGKYEYGPLLRKVLETIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: PUR7_MYCLE
Sequence: MRPALFDYRHLASGKVREIYRIDDEHLLMVASDRISAFDYVLDSTIPDKGRILTAMSVFFFSFVDAPNHLAGPPDDPRIPEEVLGRALVVRQLDMLPMECVARGYLTGSGLLDYQATGKVCGIPLPPGLVEASRFAAPLFTPAMKAVLGEHDENISFSRMIEMVGVVRANQLRDRTLQIYLQAADHALKTGIIIADTKFEFGIDRDGNLLLADEIFTPDSSRYWSVDDYRVGVVQRSFDKQFVRNWLVSPESGWVRAGALSPPSLPDDIIEATRLCYVEVYERISGMSFDDWIGPGA
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: AZOR_SHIFL
Sequence: MSKVLVLKSSILAGYSQSNQLSDYFVEQWSEKHSADEITVRDLAANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTFLGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: AROA_TRIV2
Sequence: MDTIAIPALNRPVDATVEIPGSKSITNRALLVAALAQGDSTLENALFSEDSEYFAKCVEQLGIPITLNPHLAQIQVSGKGGDIPAKQADLFVGLAGTAARFITALVALGNGEYRLDGVPRMRERPMGDLVTVLQNSGIKINFEGNSGFMPYTIYGQQFAGGHFRLKANQTSQQLSALLMIAPYAQQDTTIEVEGTLVSQSYVKMTCRLMADFGVDVTQTDDNQFHIKAGQRYQARHYTIEPDASNASYFFAAAAVTGGRVRVNHLTKQSCQGDILWLNVLEQMGCQVLEGEDYTEVIGPEQLQGIDVDMNDMSDLVQTLGAIAPYANSPVIIRNVEHIRYKETERIRAVVTELRRLGVKVEEFADGMKIEPTPINPAAIETYHDHRMAMAFAVTGLKTPGIVIQDPGCTAKTFPDYFTRFFKMIGQ
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSG_SALA4
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALTFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVGLRDKLNWFSNYYD
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: HUTU_THEAC
Sequence: MESKVREIHAPRGKTLNTKGWGQEAALRLLMNNLDPMVAKDPANLIVYGGKGKAARNWEAFDKIVQELKRLENDETLLIQSGKPVGVFKTTKDAPRVLIVNAQIVPHWATDDVFWDLEARGLTMFGQMTAGSWIYIGTQGVLQGTYETLSALARKEFGKDDLSGKWVLTSGLGEMGGAQPLAITMNNASGIVVEVDEEKIKRRLRDKYLDTWTESLDEALKMKDESLAEGKPTSIGLLGNAATVYDELMRRGIVPDVVSDQTAAHDLNLGYIPEGYTVESAAKFRDENREEYIKRVYASIVKEARAILWFQRHGSKTFDYGNNFRTRAQEGGMKDAFEIPGYVPAYIRDLFAVGSGPFRWVALSGDPQDIYRIDDAIIKNFQKDQHLVRWIKLAKERVHFQGLPARICYASYGEREEIGLMINDMVRSGDLQAPVAIGRDHHDTGSVASPYRETEKMKDGSDAIADWPILNALLNAISGATWVSVHHGGGTAIGNAIHAGFVIVADGTKDAEERIKRVLNADPGIGVIRHADAGYESSIDIIKKGPKFRYPYIN
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Probable urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCI_ECOLC
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQQIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_HALHL
Sequence: MGVTAIYPGTFDPITHGHTDLIQRGARLFDRLIVGVAANPSPSKAPAFAVEERLELARTALAGIDNVEVEAFTSLLVDFVAHHEAQVIVRGLRAVSDFEYEFQLASMNRQLRADVETVFLTPAEQYAFISSSLVREVAALGGDVSRFVHPAVAEALRNRVRRVP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTBP2_RAT
Sequence: MALVDKHKVKRQRLDRICEGIRPQIMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDLEKFKALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTVCHILNLYRRNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRRAITGRIPESLRNCVNKEFFVTSTPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPPAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ
What is the function of this protein?
Corepressor targeting diverse transcription regulators.  Functions in brown adipose tissue (BAT) differentiation.  Isoform 2 probably acts as a scaffold for specialized synapses (By similarity).
What are the official names of this protein?
C-terminal-binding protein 2, CtBP2.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
What are the subcellular locations of this protein?
Nucleus. Synapse.