PharMolix/UniProtQA huggingface dataset:
Protein: TC125_PHYPA
Sequence: MDALRKLGSLGRRRDEVDTASSPLKNEASAAEIPRDPVQISGKDEASPSGLTPIRVRVPEDVRSESEVKRDGDEESVGSGESFDSALERMEASSITSFEPPSPMESIDGRFQFEDGVREDLAESGLDGNFSYDDDDDDEEEEEDGSEEGESTSSSIINSEYSSSASNTEDEMDISGYGASSARTMLVSNDASKSDEEAIDEPKYKLRNVVTGEENMSGGLSVENEARGVALSSWKSELEDFYEASLEDNDVQEELAEKIIKVASEQNDEEDEEVHFPVIANELPGRITRNRTMIDSPAHLYSAVKAVDSTLPALKSESTKSITQGFVEAEEAESDVFTEGEDGYDDEDEDGDIQMDVSQATEKSGTPDESESNPSMGAGGPRLPSLPQRSSARRSAATTATGVPRPNTASSTQSAATSDASISSESSEANEIREKLQNIRIKFLRLARRLNQSPQNVVVAQVLYRLGLAESLRGGSSLNRTRAFSFDHANALAEEQEAAKYEDLDFACTILVLGKTGVGKSATINSIFDECKTVTSAYYPSTTKVHEVSGTVLGVKVRFIDTPGLLPSTADQRHNKNIMRQVKKYIKKVSPDIVLYFDRMDMQTRDSGDVPLLRTITDVFGAAVWFNATVVLTHASKAPPDGSNGTPMSYDYFVAQRSHFVQQTIRQAAGDARLQNPVSLVENHPACRINRSGQRVLPNGQPWKQQLLLLCFASKILAEANTLLKLQEASTPGKPFGQRSRVPPLPYLLSSLLQSRAQLKMPDEQHGESEDSDDDSDEEDEEEGDEYDDLPPFRPLSKQELEDLSKEQRQEYAEELADRERLFQKKQYREQIRRRRERKKQASVMSKEEPSIPGDGAEDESGQPATVAVPMPDMALPPSFDSDNPTHRYRYLETANQWLVRPVLETHGWDHDAGYDGFNVEKMFVVKEKIPASVSGQVTKDKKEAQVNFEAAASLRHGEGKVTLTGFDVQTIGKDLAYTVRAETRFNNFKRNKTTAGVTATYLNDTIAAGVKLEDRVLIGKRVKLVVNGGVLTGKGDKAYGGSLEATLRGKEYPLSRTLSTLGLSVMDWHGDLAIGGNLQSQFMVGKTMMVGRANLNNRGSGQVSIRASSSEQLQMVLIGIVPILRSLINCRFGFGGQPQQ
What is the function of this protein?
GTPase involved in protein precursor import into chloroplasts (Probable).  Seems to recognize chloroplast-destined precursor proteins and regulate their presentation to the translocation channel through GTP hydrolysis (Probable).  Probably specialized in the import of nuclear encoded non-photosynthetic preproteins from the cytoplasm to the chloroplast (Probable).
What are the official names of this protein?
Translocase of chloroplast 125, chloroplastic, PpTOC125, 125 kDa chloroplast outer envelope protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. TOC159 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane; Single-pass membrane protein.
Protein: MIRO3_ARATH
Sequence: MWMGVGDSSGSPKPIRIVVVGEKGSGKSSLIMAAARNTFHPNIPSLLPYTNLPSEFFPDRIPATVIDTSSRPEDKGKVVKEVRQADAIVLTFAFDRPETLDRLSKYWLPLFRQLEVRVPIIVAGYEVDNKEAYNHFSIEQITSALMKQYREVETSIQWSAQRLDQAKDVLYYAQKAVIDPVGPVFDQENNVLKPRCIAALKRIFLLSDHNMDGILSDEELNELQKKCFDTPLVPCEIKQMKNVMQVTFPQGVNERGLTLDGFLFLNTRLIEEARIQTLWTMLRKFGYSNDLRLGDDLVPYSSFKRQADQSVELTNVAIEFLREVYEFFDSNGDNNLEPHEMGYLFETAPESPWTKPLYKDVTEENMDGGLSLEAFLSLWSLMTLIDPPRSLEYLMYIRFPSDDPSSAVRVTRKRVLDRKEKKSERKVVQCFVFGPKNAGKSALLNQFIGRSYDDDSNNNNGSTDEHYAVNMVKEPGVISDTDKTLVLKEVRIKDDGFMLSKEALAACDVAIFIYDSSDEYSWNRAVDMLAEVATIAKDSGYVFPCLMVAAKTDLDPFPVAIQESTRVTQDIGIDAPIPISSKLGDVSNLFRKILTAAENPHLNIPEIESKKKRSCKLNNRSLMAVSIGTAVLIAGLASFRLYTARKQS
What is the function of this protein?
Mitochondrial GTPase that may be involved in mitochondrion development.
What are the official names of this protein?
Mitochondrial Rho GTPase 3, AtMIRO3, Miro-related GTPase 3.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: STBB_PSESM
Sequence: MILLDTNVISEPQRREPNAHVLDWIDAQALETLYLSTITVAELRAGIALMPVGKRQDSLRENLEKHLLPMFANRVLSFDMTCTKAYAELLAKSRAAGLAVETADAFIAAIALANGFTVATRDTGPFEAAGLNVINPWEA
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Involved in plasmid stability.
What are the official names of this protein?
Plasmid stability protein StbB, Ribonuclease StbB, RNase StbB, Toxin StbB.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: CLPP2_TRIV2
Sequence: MPIGVPKVPYRMPGGQFTDWISIYDRLYRERIIFLGRDVDDEIANQIIAVMLYLDSEDPGKDIYLYINSPGGMVTSGLAIYDTMQHIKSDVVTICVGLAASMGSFLLAAGTKGKRLALPHSRIMIHQPSGGTRGQATDIEIEAREILRIRHQLNQIYANNTNQPLAKIEKDMDRDFFMSAQEAKEYGLIDRVIEERI
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COLL1_DROME
Sequence: MRKHKAPPSGSPRTMAQDNSQSEPSGGNGESPAATTAAAASVEAPQQSLLLGHNAADASAAAVASRLAPPPCQHPINNSNNNSNISNNSSNSSSSKERPRPTVRFISLLHVASYVLCLCAFSFALYGNVRQTRLEQRMQRLQQLDARIVELELRLEQQQLLHWPAEQTQVLASHPSDRDSSNSNNGSQHLELHVRRELHRLRRDVSHLQLTRRQQRRQAAEAAAAAASGEGGSGGGQCQCQPGPPGPPGPPGKRGKRGKKGDSGEKGDPGLNGISGEKGAAGKPGDKGQKGDVGHPGMDVFQTVKGLKRSVTTLHGGTLGYAEIVAVKDLQEAGVNVSASTVIKLKGEPGEPGPPGPPGEAGQPGAPGERGPPGEIGAQGPQGEAGQPGVAGPPGVAGAPGTKGDKGDRGDRGLTTTIKGDEFPTGIIEGPPGPAGPPGPPGEPGARGEPGPIGPAGPPGEKGPRGKRGKRIFGPGGTKIDEDYDDPPVTLLRGPPGPPGIAGKDGRDGRDGSKGEPGEPGEPGSLGPRGLDGLPGEPGIEGPPGLPGYQGPPGEKGDRGDIGPPGLMGPPGLPGPPGYPGVKGDKGDRGDSYRKMRRRQDDGMSDAPHMPTIEYLYGPPGPPGPMGPPGHTGSQGERGLDGRKGDPGEKGHKGDQGPMGLPGPMGMRGESGPSGPSGKAGIPGAQGETGHKGERGDPGLPGTDGIPGQEGPRGEQGSRGDAGPPGKRGRKGDRGDKGEQGVPGLDAPCPLGADGLPLPGCGWRPPKEPIISTPVHKDYLPDVTQPESNTSDYEQEEEEDDEQAEDNENEYDEYQDNLHNNE
What are the official names of this protein?
Collagen alpha chain CG42342.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: RL18A_METMP
Sequence: MAKIVRIKGEIVGKDEPMVFTKEYNVLKENDALETMYSEIGSKHAVKRANIKVVEISEISVEEIQSPILKKTLEMN
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: RL11_PELPD
Sequence: MAKKITGYIKLQVPAGKANPAPPIGPALGQHGVNIMEFCKAFNAKTQADEGTITPVVITVYADRSFTFITKTPPVPVLIKKAAGIASGSAVPNKTKVGKLTKAQVEEIAKTKMPDLNAASLEAAMRTVEGTARSMGVDIV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: STAD1_OPHSP
Sequence: MELHLALLASPLPAAPGRRSLPRSSFATNSTTTINQTHLSPEKQEKLQSLLDTWAEHNLLTFLKPVEKCWQPQDFLPDPSHLSPTELGDAVREIQERAAEIPDDVWVCMVGNMVTEEALPTYQSMMSLVLGGTGADSNPWERWIRGWSAEENRHGDLLNKYLYLTGRLDMRQVEKTIQYLIGAGMDIGVDNNALCGIIYACFQEKATFISHGNTARLANHHGDTALAKICGLVAADEKRHAAAYTNLMRKLFEVDPNESMMAFAHVMQARVTMPASRMFDGRDPRLFTHFSDVSQKIGVYTVGDYSEMLEFFLKEWDISDVVDGLSPEGRRAQEYVCGLPEVMRKLAERADDRRKKLVNAGEPRYIPFSWIFNKQVRV
What is the function of this protein?
Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain.  Converts palmitoyl-ACP to (4Z)-hexadec-4-enoyl-ACP by introduction of a cis double bond between carbons 4 and 5 of the acyl chain.
What are the official names of this protein?
Palmitoyl-[acyl-carrier-protein] 4-desaturase 1, chloroplastic, Acyl-[acyl-carrier-protein] desaturase 1, Stearoyl-[acyl-carrier-protein] 9-desaturase 1, Stearoyl-ACP desaturase 1.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ARGR_STAA2
Sequence: MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSRDIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPGNAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_MOUSE
Sequence: MGIHGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSLMGMFYRTIRMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQQAQEAGMEEEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALAKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRVLQELGLNQEQFVDLCILLGSDYCESIRGIGAKRAVDLIQKHKSIEEIVRRLDPSKYPVPENWLHKEAQQLFLEPEVVDPESVELKWSEPNEEELVKFMCGEKQFSEERIRSGVKRLSKSRQGSTQGRLDDFFKVTGSLSSAKRKEPEPKGPAKKKAKTGGAGKFRRGK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: DPHB_METM5
Sequence: MLVMAGLGLYDERDVTLKTLDFAKKVDKIYAEFYTAILTGTTMEKVEETLQKPITVLDREKVEYETNKLIEEAKDKDIMFLTAGDPMVATTHVDIAVEARKKGIEVVIINAPSIYSAIGITGLQLYKFGKTTSIVFPEPNYFPETPYDVIKDNLKLGYHTLCLLDIQADKERFMTANEGLSALLEIEEKRNENVISGETHAAVVARAGSTKPGLYYGKIKDLINYDFGTPLHCVIIPGKLHFMEEDALKYLFENI
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RNH2_THEM4
Sequence: MIVAGVDEAGRGPLFGPVVASAVVLKKEIYGITDSKKLTLKQREELFMEIIRNSYFGIGFASSSEIDKLNILHATELAMNRALAMLERKIRFDMVLVDGKNLKLDYKSKCIVKGDVLIKEISAASIIAKVVRDKIMTFYSKKFSNYALEKHKGYPTKDHIKLIEKYGLTPEHRLTFKPITKMLSINKLEEWYKSDIIDEERYKKIIEKLGVPLFGV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_STUS1
Sequence: MKTFTAKPETVKRDWFVVDAAGQTLGRLATEIASRLRGKHKPEYTPHVDTGDYIVVINAEQVRVTGAKTSDKMYYSHSGFPGGIKSINFEKLIAKAPERVIETAVKGMLPKNPLGRDMYRKLKVYKGANHPHTAQQPQELKI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y755_GLUOX
Sequence: MSDACIYCKTAQRCPSDMIQAGPVALIRKLRWLYAPDPVMAGYALRTTCTSLLALGIALWMELGSPQWAALTVWMVAQGTRGRSLAKAKWHLFGMVVGVISGITLVAAIPQAPLMFILLLAVGIGTFCMIGTFMPGPASMTNYRIHGMRASGFTYAIVSLDGIADPHHIFAISMSRATYILLGIVLEASISGLFQLGLTKRTRHQLASTFEDTLKPALTAIAGILVGKEGAMQNVQAIFAQITTLGDQVEFAEVELGRHDHAGDHARAALADIAVLLARALDLATLMRLPLSQDDMFRQEAEAIRDMFLKLPARLEETESMASILADLLTLRRQCRQKVVSDFSTAQPDDAAREAVLRHGMLQQALVELIDALRMALTQFEASRHPGSHDHFHSPIRSYRDWQQAITNSLRSSVTVFGAGLIWICTAWPSGLTFIMFVCIVCSLFSTLERPALATQAFLRGACCAVVAAGILNLALMGKSTTFEMLGMWSGLAMMIGGLAFAYPPLTLPAVSYNLFLPILIGPSNQAKTDEIVYFNTALPLVLGLLYASWMYRVFLPYDPAHQRWTMREHILRDLHRIADGRAQETVDSVVSRNVDRFVRLMTNSGSTPSPVIQAYLTGILSGMRVMLNLLRLQAIRRDTRLNPEAGQALALIMGRMSHFSGRYHGHYGRTLRATKLAILRLRTCERNEDRPRERFVLIAALTSLDVIATELDTNRIFFDARSPYLDPSLTPAELESTG
What are the official names of this protein?
Uncharacterized transporter GOX0755.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2288_MYCTO
Sequence: MSRRRPLIEPATVQVLAIAFTDSFSVSLHWPQREQGCRTAILAPMRRWCDGDVDGRKLLPPARRTGTQQRRIRPAAPRVYTTGDILRDRKGIAPWQEQREPGWAPFGWLHEPSGARCPKADGQSV
What are the official names of this protein?
Uncharacterized protein MT2345.1.
Protein: PHT15_PETHY
Sequence: MASNNLNVLNALDTAHTQWYHVTAVVIAGMGFFTDAYDLFCISTISKLLGRLYYYDPHTHAPGKLPHTVNNWVTGVALVGTLTGQLVFGWLGDKLGRKKVYGLTLILMVICALSSGLSFGYSRKVVIGTLCFFRFWLGFGIGGDYPLSATIMSEYANKRTRGAFIAAVFAMQGVGIIFAGLVLMTVSKVFLMRYAGKAFSTDEVFSTEPEADYVWRIVLMLGALPALLTYYWRMKMPETGRYTAIIEGNAKQAAIDMGKVLEIEIQAEGEKLAKFKSANDYSLLSNEFFQRHGLHLIGTMSTWFLLDIAFYSQNLTQKDIFPTMGLVSDAKSISALREMFETSRAMFVIALLGTFPGYWFTVFFIEKIGRFKIQLMGFFMMSIFMAIIGVRYDYLKTKDHKWTFAALYGLTFFFANSGPNSTTFVLPAELFPTRVRSTCHALSAASGKAGAMVSAFGVQQYTQDGEVHKIKKAMLFLAFTNMVGFCCTFLVTETKGRSLEEISGEDENQNETKMKGRPVSGGHQDDGWD
What is the function of this protein?
Low-affinity transporter for external inorganic phosphate (Pi) probably involved in the acquisition of phosphate released by arbuscular mycorrhizal (AM) fungi during AM symbiosis.
What are the official names of this protein?
Low affinity inorganic phosphate transporter 5, PhPT5, PhPht1;5, Arbuscular mycorrhiza-induced phosphate transporter PT5, AM-induced phosphate transporter PT5, H(+)/Pi cotransporter PT5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. phosphate:H(+) symporter (TC 2.A.1.9) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Present on the periarbuscular membrane in cells containing arbuscules during arbuscular mycorrhizal (AM) symbiosis with AM fungi.
Protein: CT5D_CONTE
Sequence: NIQIICCKHTPACCT
What are the official names of this protein?
Conotoxin tx5d, Trixin.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YCCT_SHIFL
Sequence: MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLLRGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLENEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASLPQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQPSS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: TRPC_STAES
Sequence: MTILNEIIEYKKTLLERKYYDKKLEILQDNGNVKRRKLIDSLNYDRTLSVIAEIKSKSPSVPQLPQRDLVQQVKDYQKYGANAISILTDEKYFGGSFERLNQLSKITSLPVLCKDFIIDKIQIDVAKRAGASIILLIVNILSDDQLKELYSYAINHNLEVLVEVHTIRELERAHQINPKIIGVNNRDLKRFETDVLHTNKLLKFKKSNCCYISESGIHTKEDVEKIVDSNIDGLLVGEALMKTNDLSQFLPSLKLKKNLYDS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: BIOD_FRATW
Sequence: MKKFFIIGTDTEVGKTYISTKLIEVCEHQNIKSLCLKPVASGQSQFSELCEDVESILNAYKHKFTAAEINLISFNQAVAPHIIAAKTKVDISIENLKQFIEDKYNQDLDILFIEGAGGLLTPYSDHTTQLDLIKALQIPVLLVSAIKVGCINHTLLTINELNRHNIKLAGWIANCNDSNIKYIDEQINTIEELSGYKCSAKISRNADYLDFIDLSKILISPEENE
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MD2L2_CHICK
Sequence: MTTLTRQDLNFGQVVADVLSEFLEVAVHLILYVREVYPIGIFQKRKKYNVPVQMSCHPELNQYIQDTLHCVKPLLEKNDVEKVVVVILDKEHHPVERFVFEITQPPLLSISSESLLSHVEQLLRAFILKISVCDAVLDNNPPGCTFTVLVHTREAATRNMEKIQVIKDFPWILADEQDVHMHDPRLIPLKTMTSDILKMQLYVEERAHKGT
What is the function of this protein?
Adapter protein able to interact with different proteins and involved in different biological processes.  Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis.  Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions.  May also play a role in signal transduction in response to DNA damage.  May regulate the activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle.  Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs).  During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (By similarity).  Through transcriptional regulation may play a role in epithelial-mesenchymal transdifferentiation.
What are the official names of this protein?
Mitotic spindle assembly checkpoint protein MAD2B, Mitotic arrest deficient 2-like protein 2, MAD2-like protein 2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Chromosome.
Protein: PYRG_PHOLL
Sequence: MKTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMTRRNNFTTGRVYSEVLRKERRGDYLGATVQVIPHITNEIKDRIISGGEGHDVVLVEVGGTVGDIESLPFLEAIRQMAVEVGREHTLYLHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRVIPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLDCPEANLSEWEQVIYEEANPSGEVTIGMVGKYVELPDAYKSVIEALKHGGLKNRLTVNIKLLDSQDVETRGVELLKGLDAILVPGGFGGRGVEGKIMTARYARENNIPYLGICLGMQVALIEFSRHVAGLEKASSTEFEPDCRLPVVGLITEWRDEDGNLEVRSEESDLGGTMRVGGQPCHLTKDSLVRTLYGADTIVERHRHRYEVNNLLLKRIEDAGLRVAGRSVDNKLVEIIEIPDHPWFVACQFHPEFTSTPRDGHPLFTGFVKAAGKYQKGQLK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: APAH_ACTP7
Sequence: MATYIVGDLHGCFDELQLLLKQVNYNPAQDELWLTGDLVARGAKSLECLRFVKDPKNNAKTILGNHDLHLLATLLGVKKVKPNDQVDAIFAAEDRADLQNWLRNQPLLIQHPKYGFLLTHAGISPEWNLTETIACAREAEAVLQSGHYADYIAQMYENTPDHWSAEWQGIERWRYIINVFTRMRFCYADKRLDFACKLPVEDAPNELKPWFKLDNPLFHQQDIIFGHWASLMGKADKPNIYALDTGCAWGNHLTMIRWEDKQIFTQERLK
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: VSP17_CRODU
Sequence: MVLIRVLANLLILQLSYAQKSSELVIGGDECNINEHRLLAIVYTNSSQCAGTLINQEWVLTAAHCDGENMDIYLGVHNESVQYDDEEGRVAAEKFFCLSSRNYTKWDKDIMLIRLNIPVRNSTHIAPLSLPSSPPSVGSVCRVMGWGTITSPNETYPDVPHCANINLFDYEVCLAAYPEFGLPATSRTLCAGIQQGGKDTCGSDSGGSLICNGQFQGIVSWGDNPCAQPHKPALYTKVLDDTEWIQSIIAGNTAVTCPP
What is the function of this protein?
Thrombin-like snake venom serine protease.  Displays a specificity similar to trypsin.  Releases only fibrinopeptide A in the conversion of fibrinogen to fibrin.  Shows coagulant, esterase and amidase activities (By similarity).  Reversibly increases the permeability of the blood brain barrier (BBB) in mice.  Induces the barrel rotation syndrome in mice, which is manifested by gyroxin-like, rapid rolling motions.  This syndrome may be due to its effect on BBB permeability, and certainly also to other actions affecting endogenous substrates present in the endothelium, nervous tissues or blood.
What are the official names of this protein?
Thrombin-like enzyme gyroxin B1.7, SVTLE gyroxin B1.7, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COFC_METKA
Sequence: MRFVVPFADRGDRKTRLSSCMDEETRERFALAMLRHVVRVLSKFGEVEVVTPDSSLSVPGTKVRRSDASLDELPLPDGEFGLVMSDLPLLSEEDVERALEGLKDADVVLCPSRRGGTSGVFVRKGVRFRPTFGGVSFPRNLRRAEKQGVEVAVVKSLGFFADVDEPEDLLDAALLGRREVAKIARSVVEV
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
2-phospho-L-lactate guanylyltransferase, LP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: EFP_SALTY
Sequence: MATYYSNDFRSGLKIMLDGEPYAVESSEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNA2_XENLA
Sequence: MSDHLLRDEHQENVQPRKLLVPVGGRTVLGVLQENHRGPKALKVSKPALQQTQVLSVNHLGVNDENYGKIPARKAASKQPAFTIHVDEPDCATNKRKAVHKKTVQDENLQQLNSVLGSIGTRKPLHPIQIAMETSFGSPMDVSIVDEEQKVVGCNNVADYAKEIHTYLREMEVKCKPKAGYMQKQPDITGNMRAILVDWLVEVGEEYKLQNETLYLAVNYIDRFLSSMSVLRGKLQLVGTAAMLLASKFEEIYPPEVAEFVYITDDTYTKKQVLKMEHLVLKVLSFDLAAPTILQYLNQYFQIHPVSPKVESLSMFLGELSLVDADPFLRYLPSVVAAAAFVIANCTINERTWSDPLVEYTSYTLETLKPCILDLYQTYLSAASHQQQAVREKYKAPKNHAVSLIIPPESMSTFL
What is the function of this protein?
Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle.  Functions through the formation of specific serine/threonine kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 and CDK2.  The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
What are the official names of this protein?
Cyclin-A2, Cyclin-A.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ARGB_NEIG2
Sequence: MEFENIISAADKARILAEALPYIRRFSGSVAVIKYGGNAMTEPALKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKVGKKGEFVQGMRVTDKETMDIVEMVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLVDTPEQNSVDIGQVGTVESIDTGLVKGLIERGCIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKTGNLLTKLTPKRIDGLIADGTLYGGMLPKIASAVEAAANGVKATHIIDGRLPNALLLEIFTDAGIGSMILGRGEDA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.