PharMolix/UniProtQA huggingface dataset:
Protein: NU2C1_CALFG
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFHGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPESFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALISITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFARIVSFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSLLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RRF_SYNAS
Sequence: MKDMVFDELKQNMEKGLQALEKSFNKVRTGRASISLLDGIKADYYGTPTPLNQVATLSVPESRQILISPWDTSALNAIEKAIQKSDLGLVPNNDGKVIRISIPPLTEARRKELVKVVRKMAEECKVKLRNARRDANEEFKSMKKNNDISEDQMHDYQDQVQKMTDSYIEKSEDILVQKEKEIMEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCAT5_ARATH
Sequence: MERSAVASGFHRNYILCASRAATSTTRLHSLSSLRNFPSSSLRIRHCPSPISSNFIVSEVSRNRRCDAVSSSTTDVTELAEIDWDKIDFGLKPTDYMYAMKCSRDGEFSQGQLQPFGNIDINPAAGVLNYGQGLFEGLKAYRKQDGNILLFRPEENAIRMRNGAERMCMPSPTVEQFVEAVKTTVLANKRWIPPPGKGSLYIRPLLMGTGAVLGLAPAPEYTFLIFVSPVGNYFKEGVAPINLIVETEFHRATPGGTGGVKTIGNYAAVLKAQSIAKAKGYSDVLYLDCLHKRYLEEVSSCNIFIVKDNVISTPEIKGTILPGITRKSIIEVARSQGFKVEERNVTVDELVEADEVFCTGTAVVLSPVGSITYKSQRFSYGEDGFGTVSKQLYTSLTSLQMGLSEDNMNWTVQLS
What is the function of this protein?
Converts 2-oxo acids to branched-chain amino acids.  Acts on leucine, isoleucine and valine (By similarity).
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase 5, chloroplastic, Atbcat-5.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MED27_AEDAE
Sequence: MNLEPINNALSHLRMLRSSVGQVFETLGNGVRAEHGEEGKEQKFLQELQELLNGVNSNLREFETCINDLTPPQAPFNLANTAYLSLETNLERQALYPHLVQSYKWHDKLHEYSTFASVLLQQNSLKRSYYTNTKRRRSLPSSHLATPQTVDNLIGSIHFPNMNLKIVRPFMTNAILHITIARVLRAAVILKGLLIEWVTVKGFDESLLDGVDEHWTVSRHQVFRKVQDHAHSAMLHFFSPTLPDLAIRSFITWFRSYLTLFADPCKKCGKHLHNTLPPTWRDLRTLEPYHEECKQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 27, Mediator complex subunit 27.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 27 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LPXK_PSEA7
Sequence: MSFSERLLAAWYRGHPALALLRPLEALYRRVVNARRADFLSGRKPAYRAPVPVVVVGNITVGGTGKTPMILWMVEHCRARGLRVGVISRGYGARPPHAPWRVRPEQDAAQAGDEPLMIVRRSGVPLMIDPDRPRALRALLAEEPLDLVLCDDGLQHYRLARDLELVLIDAARGLGNGRCLPAGPLREPRERLESVDALLYNGADEDPEDGFAFRLRPAALVNLQSGERRALGYFPAGQMLHAVAGIGNPQRFFGTLEALHWRPIPHAFPDHATYSATELTFDPPLPLLMTEKDAVKCRAFAAADWWYLAVDAVPSPAFVAWFDARLEHLLAR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: THIE_ECOUT
Sequence: MYQPEFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLSAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PLSX_LACAC
Sequence: MRTIAIDAMGGENAPEAIVKAVLKAKNEMPETKFLLFGDKEQLRELIPADQINDQLGVVATTETIADEDEPVKAIRRKKDSSMVVAANFVKEGKADALLSLGNTGALLACGIFIIGRIKGIVRPGLMPTLPVQNSDDGFNMVDVGANAKSKPEYLLQWAEMASYYAQKIRGIDNPRIALLNNGAESDKGDDVHQKAYELLKDSDLNFVGNIEGNELLLGNADVVVTDGFTGNAVLKNIEGTSSVILHLLKDSLLNGNLMTKMGALMVKGSLASLKSKFDTAKYGGAVLLGVNAPVVKTHGRSNERPIYYTLKQVDKMIKEKLVEDFRDEFSEK
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: HIS1_RHIME
Sequence: MTVTIALPSKGRMKDEASAIFERAGMKIAAVGSDRSYRGRVEGWDDVEIAYLSASEIAREIGSGAVDFGVTGEDLVREGLADADARVDFAARLGFGHADVVVAVPEIWYDVDTMADLGDVAADFRARHGRRLAIATKYWRLTQQFFSGSHGIQLYRIVESLGATEGAPASGSADIIVDITSTGSTLKANHLKILSDGVILRSEACLVRARKATHEGNPVIDRIVAAVRAVL
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF415_TOBAC
Sequence: MAGAAPEGSQFDARQFDTKMNELLSADGQDFFTSYDEVYDSFDAMGLQENLLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGILQQLAYELLECQALVLAPTRELAQQIEKVMRALGDYLGVKVTACVGGTSVREDQRILSSGVHVVVGTPGRVFDMLRRQSLRPDHIKMFVLDEADEMLSRGFKDQIYDIFQLLPPKIQVGVFSATMPPEALEITRKFMNKPVRILVKRDELTLEGIKQFYVNVDKEEWKLETLCDLYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINFDLPTQPENYLHRIGRSGRFGRKGVAINFVTKDDERMLSDIQRFYNVVIEELPANVADLL
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-15, eIF-4A-15, ATP-dependent RNA helicase eIF4A-15.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: DHON_METGL
Sequence: MKPINVGLLGIGTVGGGTYTVLTRNQEEIARRAGRPIAITRVADRNLELARQVTGGKIDVTDDAFAIVSDPAIDIVVELIGGYTVARELVLKAIENGKHVVTANKALIACMAMKFLPLRRKKASSSLLKLPLLVVSPLFKAVREGLAANRIEWIAGIINGTTNFILSEMREKGLAFADVLKEAQRLGYAEADPTFDVEGIDAAHKLMILAAMLWLFVHSLCRGITKLDAVDITKRTDKGVELRVHPTLIPEKRLICQCEWRNECCAGQGRCCWPTLYYGAGAGAEPTASAVADLVDGTDRGISCPHLAFQPDRLVDLPILPIGEISSAYYLRLRAVDKPGVLADVTRILGDRQISIDAMIQKEPQEGEDQADIIILTHVTVEKNMDDAIAAIEALPAISGKVTRLRMEELSR
What are the official names of this protein?
Homoserine dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the homoserine dehydrogenase family.
Protein: SKGR_XENLA
Sequence: METMYHRFLCIPFLLILGLAQGQSKGLQTVTTFRTGLKPIDVTAIRTGLQPIATFHTGQKPIDVTAIRTGLQPIATFHTGLQPVDVTAIRTGLQPIATFQTGVQRVSTFHGEPASTLQGSGSTVIKKIMVSSMNQPVSKNEGIVEVPPPSGGTHVITEEMNWHGGRNGHKMKKLGKKKHHKNRHGGKNHHKMKKIGKHHGGGRKFGKKHRHHK
What are the official names of this protein?
Skin granule protein.
What are the subcellular locations of this protein?
Secreted.
Protein: LGUL_MOUSE
Sequence: MAEPQPASSGLTDETAFSCCSDPDPSTKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQKLDFPAMKFSLYFLAYEDKNDIPKDKSEKTAWTFSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKIATII
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:18695250).  Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity).  Required for normal osteoclastogenesis (PubMed:18695250).
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: OBSL1_HUMAN
Sequence: MKASSGDQGSPPCFLRFPRPVRVVSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGPILKRLPRKLDVLEGENAVLLVETLEAGVEGRWSRDGEELPVICQSSSGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPPILAEMFKGHKNTVLLTWKPPEPAPETPFIYRLERQEVGSEDWIQCFSIEKAGAVEVPGDCVPSEGDYRFRICTVSGHGRSPHVVFHGSAHLVPTARLVAGLEDVQVYDGEDAVFSLDLSTIIQGTWFLNGEELKSNEPEGQVEPGALRYRIEQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDRVSLTFTTSERVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEGVSAFFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSSWIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDAGEYLCDAPQDSRIFLVSVEEPLLVKLVSELTPLTVHEGDDATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLRPLEDVTISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVSFTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHPPREKTVLVGRRAVLEVTVSRSGGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSTHTRLLVEGN
What is the function of this protein?
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity.  It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696).  Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain.  Required to localize CUL7 to the Golgi apparatus in neurons.
What are the official names of this protein?
Obscurin-like protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Golgi apparatus. Note=Colocalizes with CUL7 at the Golgi apparatus in neurons (PubMed:21572988).
Protein: XYNB_BUTFI
Sequence: MNLKTAYEPYFKIGAAISRWNLHTPAHTKLLAEQFNSFTCENDMKPMYYLDREANKKDPEKYNLSPALTFENAIPYLEFAKDNKIAMRGHTLVWHNQTPKWFFCERYNENFPMADRETILARLESYIHGVLDFVQTNYPGIIYAWDVVNEIVDEGAFRKSIWTETVGEDFFIKAFEFARKYAAPEVSLFYNDYETAQPWKRDFILEKVLGPLIDKKLIDGMGMQSHLLMDHPDISEYRTALEMYGSTGLQIHITELDMHNADPSEESMHALATRYQEFFQTYLDAKKSGKANITSVTFWNLLDENSWLSGFRRETSYPLVFKGKCEAKEAYYAVLKAAVSDDSIDKWVPDYSEEDYKLQGMPTPDIKRFRENIWQENEYNYEASYGFIPNLFAYLHNDDVKRDCMLVIPGGGYCMCCSHEGELAAMEFYNRGMNAFVLSYTTDITMSVPLHKQPLEDISRAVRFIRKNASKYNIDGKKLVIMGFSAGSHVCGSLAVHFDDVKDNNPEYADISGRPDGVILSYPVITTGRYTHADSVRTLLGANPTDEELTYFSLEKQVKDNTPPCFIWQTEEDSVVPVENSYLFANALREKKIPFAHYVFPRGFHGLTVANDEFFSGWSGGEYSMEQTMRARFAV
What is the function of this protein?
B. fibrisolvens is located in the rumen of ruminant animals, where it contributes to the animal's digestion of plant material by hydrolyzing hemicellulose with its xylanases.
What are the official names of this protein?
Endo-1,4-beta-xylanase B, Xylanase B, 1,4-beta-D-xylan xylanohydrolase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Protein: CODY_STRSV
Sequence: MADLLEKTRKITSILKRSEEQMQEDLPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNNDRVEAFFQDKNFPEEYVQEANLVYETEANLPVTHDLTIFPVETKDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKEFADDDLILVEIASTVVGIQLLNFQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGQLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVLIPDVFDEIKKRDY
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUN1_DROME
Sequence: MKTETGSNNNNTTVVNMDFDMYPSISGKQQDPVREVVMKYIDYFLPDASGTSAVAIDNKIEQAMDLVKSHLMIAVREEVEVLKERISELMDKINKLELENSILKSNIPQETLQQLQLQLQLAAPPATPAIQAAPAVQSVVAPAAAGQAVQQQAAGAVAVTGVATSPASAVVPTSIPNGSAENGSSAVESAAVSVEQQVQQVTSAAAAAASVVTANGPMS
What is the function of this protein?
Probable transcription factor required for peripheral nervous system morphogenesis, eye development and oogenesis.  May be required for the transmission of the dpp signal and for a morphogenetic movement of the medulla in the brain that reorients the second optic lobe relative to the first.  Plays a role in determining proper dorsal cell fates leading to the formation of the dorsal appendages.
What are the official names of this protein?
Protein bunched, class 1/class 3/D/E isoforms, Protein shortsighted.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ANKY2_CHICK
Sequence: MAPPRKGELSPEEKDLLGVIAKGNVEEAGRLLGSKNVHVNCLDEHGMTPLMHAAYKGKVDMCRLLLRHGADVNCNEHEHGYTALMFAGLSGNKEITWMMLEAGAETDVVNSVGRTAAQMAAFVGQHDCVTIINNFFPRERLDYYTKPQGLDKEPKLPVKLAGPLHKIITTTNMHPVKIVLLVKENPLLAEVEALQKCYRVLDLICEKCMKQKDMNEVLAMKMHYISCIFQKCVTFLKEREDKLDGFIKSLLKGRDKDGFPVYQEKLIRESIRKFPYCEATLLQQLVRSIAPVELGSDPTAFSVLTQAITGQVGFVDAEFCTTCGEKGADKRCSVCKVVMYCDQNCQKTHWFTHKKVCKTLKEIHEKQELEAAKEKRRQEKKQKKDEAQLEEAGATSEEQSAPGPDATKEADPNLWIQTDQTEETELTKEPEARAPRPDSPLESETALADIALQKIQDSEE
What is the function of this protein?
May be involved in the trafficking of signaling proteins to the cilia.
What are the official names of this protein?
Ankyrin repeat and MYND domain-containing protein 2.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: PURQ_AQUAE
Sequence: MKFAVCVFPGSNCDYDTYYVIRDILEKDVEFVYWEEKNLSKYDVVVLPGGFSFGDYLRPGALAARTPLAQAIYDFAQKGKYVIGICNGFQILTELGLLPGALLPNLNMRFVCKWVNLRVENERSAFTRKLEKGDVLRIPIAHHDGRYYVPEEELRKMEENGQILFRYCDEQGEVKEEVNPNGSVSNIAGVMNKEGNVFGMMPHPERASEDILGSHDGLMLWYSLLSD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_WOLPP
Sequence: MTFSVTILTIFPEMFPGFLNYSLAGKALEKKIWNLEIVNIRSFAKDKHSTVDDVPYGGGAGMVMRPDVIGNAVDNVLSAHKNTRFIYMTPSGTKFNQRIAKELTEIPHVTILCGRFEGVDQRVIDVYTPYELSIGDYILSGGEPAAMVVLDACIRLLPGVVNNFDSVAEESFSYSGGILEYPQYTRPEQWSRYKVPEVLLSGNHRKISDWRREQSYVRTKERRPELLNGDDK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DN7B_SULIH
Sequence: MTTVKFKYKGEEKQVDTSKIKKVWRVGKMISFTYDEGGGKTGRGAVSEKDAPKELLQMLEKQKK
What is the function of this protein?
Can constrain negative DNA supercoils.  May be involved in maintaining the integrity of the genome at high temperature.
What are the official names of this protein?
DNA-binding protein 7b, 7 kDa DNA-binding protein b, Sis7b.
What is the protein family that this protein belongs to?
Belongs to the 7 kDa DNA-binding/endoribonuclease P2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_XANAC
Sequence: MAVSARDYWDLTKPKVVALIVFTALVGMFLAIPDMPTWLQVRTGALGFLGIWLAASAAAAINQLLDAKIDAQMARTSWRPLVVGKVRPWQVLVFAGVLIVISMTILVVWVNVITAVLTFASLIGYAVIYTVYLKRATSQNIVIGGLAGATPPMLGWAAVTGLPTSADWINASLLVLIIFIWTPPHFWALAIFRRADYAKAAIPMLPVTHGVPHTRKQILVYTVLLAIVTLAPVAVGMSGMFYLGGAAVLNAVFLWYAWRMLNPPDELFSMKMFGYSIVYLMALFAFLMVDHLLLPWVR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_OCETE
Sequence: MAPNPRKSHPLLKMINNSLIDLPAPSNISAWWNFGSLLALCLMTQILTGLLLAMHYTADTTLAFSSVAHTCRDVQYGWLIRNMHANGASFFFICIYLHIGRGFYYGSYLHKETWNTGVLLLLTLMATAFVGYVLPWGQMSFWGATVITNMFSAIPYIGQTIVEWAWGGFSVDNPTLTRFFALHFLLPFMIAGLTLIHLTFLHESGSNNPLGIVSNCDKIPFHPYYSLKDALGLALLLLPLTTMALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLSPLLHKSKQRTMAFRPLSQLLFWTLVANLLILTWIGSQPVEHPFIIIGQLASTTYFIILLILFPITSALENKMLNF
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RAC10_ARATH
Sequence: MASSASKFIKCVTVGDGAVGKTCMLICYTSNKFPTDYIPTVFDNFSANVVVEGTTVNLGLWDTAGQEDYNRLRPLSYRGADVFVLSFSLVSRASYENVFKKWIPELQHFAPGVPLVLVGTKLDLREDKHYLADHPGLSPVTTAQGEELRKLIGATYYIECSSKTQQNVKAVFDSAIKEVIKPLVKQKEKTKKKKKQKSNHGCLSNVLCGRIVTRH
What is the function of this protein?
Involved in local disassembly of cortical microtubules when associated with ICR5 and KIN13A.
What are the official names of this protein?
Rac-like GTP-binding protein ARAC10, GTPase protein ROP11.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited along cortical microtubules upon interaction with ICR5.
Protein: CDYL2_MOUSE
Sequence: MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHLSKDKRVKSGKQAGASKLLRDARGLPVERLSHRPLEPGKSKPSSHKRKRVNSPLSRPKKGSSGKAPDRATKTVSYRTTPSGLQIMPLKKAQNGLENGDAGSEKDESHFGNGSHQPDLELNDQLGEQEASDCDGTHSALVENGVGSALTNGGLNLHSPVKRKLETEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEEVNEKECVMLKQLWSSSKGLDSLFSYLQDKIYEV
What are the official names of this protein?
Chromodomain Y-like protein 2, CDY-like 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCZ1_DANRE
Sequence: MLMISPRMASGMQEKQYTPSLLSFFIYNPKFGPREGEEEKKILFYHPIEIEKNEKIRNVGLCEAIVQFTRTFCPTKPAKSLHTQKNRQFFHEPEENYWMVMVVRNPMVEKPNKDGKPPTVEYQEEEIIDSVYGSVLQQCYSMYKLFNGTFSRAFEAGGVELLTQKLEKFFYRYLQTLHLQSCDLLDVFGGISFFPLDKMTYLKIQSFVNRVEESLSLVKYTAFLYNDQLIWSGLEQDDMRILYKYLTTSLFPRHTEPELAGRDSPLRPEVAGNLLHYGRFLTGPANLKDPEAKFRFPRIFVNTEDSCEELHLIVYKAMSAAVCFMINASVDLNREFCEKLDSLVGPQLTLLASDICEQYNINRRISGPEKEPQFKFIYFNHMNLAEKSTIHMRKMASVSLTSVHPDLMKILGDINCDFARVDEDEEIIVKAMTDYWVVGKKSDQRELYVILNQKNANLIEVNEEVKRLCATQFNNIFFLD
What are the official names of this protein?
Vacuolar fusion protein CCZ1 homolog.
What is the protein family that this protein belongs to?
Belongs to the CCZ1 family.
What are the subcellular locations of this protein?
Lysosome membrane.