PharMolix/UniProtQA huggingface dataset:
Protein: MUTS_ESCF3
Sequence: MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLENVDSAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: MCPT1_RAT
Sequence: MQALLFLMALLLPSGAGAEEIIGGVESRPHSRPYMAHLEITTERGYKATCGGFLVTRQFVMTAAHCKGRETTVTLGVHDVSKTESTQQKIKVEKQIVHPNYNFYSNLHDIMLLKLQKKAKVTPAVDVIPLPQPSDFLKPGKMCRAAGWGQTGVTKPTSNTLREVKQRIMDKEACKNYFHYNYNFQVCVGSPRKIRSAYKGDSGGPLVCAGVAHGIVSYGRGDAKPPAVFTRISPYVPWINKVIKGKDLTSLSLHESESPS
What is the function of this protein?
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.  May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits.
What are the official names of this protein?
Mast cell protease 1, rMCP-1, Chymase, Chymotrypsin-like protease, CLIP protein, Mast cell protease I, rMCP-I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule. Note=Mast cell granules.
Protein: NADK_TERTT
Sequence: MQSFNTIGLIGRLASASTQYSLKRLIAFLTDQKLEVLLDKETSTILPDCDLPVATRPELAQACDLIIVVGGDGSLLSAARAFAGHDVQILGINRGRLGFLTDISPEDIENKVGEVLSGRYLLEQRFLLESTLLRDDEVMSTGLALNDVVIHPGKLIRMIEFELYIDDEFVYRQRSDGLIISSPTGSTAYALSGGGPIMHPNLDAVVLVPLYPHTLSSRPIVVGGNSEIRLIVCENNNLNPLVTCDGQSQTMTQPGDTVFITKSEKRLKLIHPEGHNFYETCRSKLGWASHTGN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGPC_SHIFL
Sequence: MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPLLPIIAIALLIKGRAARWPMSLLLWGCTFGHSEARLQTLQADFVRWFRDNVTAFPLVQERLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCLGHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE
What is the function of this protein?
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).
What are the official names of this protein?
Phosphatidylglycerophosphatase C, Phosphatidylglycerolphosphate phosphatase C, PGP phosphatase C.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MO25M_ARATH
Sequence: MRGLFKSKPRTPADIVRQTRDLLLYADRSNSFPDLRESKREEKMVELSKSIRDLKLILYGNSEAEPVAEACAQLTQEFFKADTLRRLLTSLPNLNLEARKDATQVVANLQRQQVNSRLIAADYLESNIDLMDFLVDGFENTDMALHYGTMFRECIRHQIVAKYVLDSEHVKKFFYYIQLPNFDIAADAAATFKELLTRHKSTVAEFLIKNEDWFFADYNSKLLESTNYITRRQAIKLLGDILLDRSNSAVMTKYVSSMDNLRILMNLLRESSKTIQIEAFHVFKLFVANQNKPSDIANILVANRNKLLRLLADIKPDKEDERFDADKAQVVREIANLKLRELA
What are the official names of this protein?
Putative MO25-like protein At4g17270.
What is the protein family that this protein belongs to?
Belongs to the Mo25 family.
Protein: AROQ_SHEWM
Sequence: MSAKAKILLVNGPNLNLLGRREPGHYGHHTLDSIVQNMKNTANSADVELEHIQSNAEHELIDAIHSTDANFIIINPAAFTHTSVAIRDAILGVAIPFIEVHLSNVHAREPFRHHSYFSDKAVGVICGLGADGYQFALKSAINRLQGPSA
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PSA1_YEAST
Sequence: MSGAAAASAAGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQD
What is the function of this protein?
The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  It has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-1, Macropain subunit C7-alpha, Multicatalytic endopeptidase complex C7, Proteasome component C7-alpha, Proteasome component Y8, Proteinase YSCE subunit 7, SCL1 suppressor protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS17_RICPU
Sequence: MPKRVLQGVVISSKADKTVTVKVERKFKHPIYKKFVKVSKKYAAHDSENKYQEGDKVSIIESRPISKTKTWVVVNGE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PYRB_CUPTR
Sequence: MTKTFRNPQLTKNGELKHLLSIEGLSRDMITHILDTASQFVSLSDSDRDVKKVPLLRGKSVFNLFFENSTRTRTTFEIAAKRLSADVLNLNINASSTSKGESLLDTINNLSAMSADMFVVRHASSGAPYLIAEHVAPHVHVINAGDGRHAHPTQGLLDMYTIRHFKKDFTNLTVAIVGDILHSRVARSDIHALTTLGVPEVRAIGPRTLLPSGLEQMGVRVFHSMEEGLKGVDVVIMLRLQNERMSGALLPSAQEYFKAYGLTPERLALAKPDAIVMHPGPMNRGVEIDSAVADGAQSVILNQVTFGIAVRMAVMGIVAGNND
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: P2C33_ORYSJ
Sequence: MESAAGEEGKAAPSLPLATLIGRELRGGGSERPLVRYGHFGFAKRGEDYFLVKPDCLRVPGDPSSAFSVFAVFDGHNGVSAAVFSKEHLLEHVMSAVPQGIGRDDWLQALPRALVAGFVKTDIDFQRKGEASGTTATLVVVDGFTVTVASVGDSRCILDTQGGVISLLTVDHRLEENVEERERVTASGGEVSRLNLCGGQEVGPLRCWPGGLCLSRSIGDTDVGEFIVPIPHVKQVKLSNAGGRLIIASDGIWDALSSEAAAQACRGLPAELAAKLVVKQALKTSGLKDDTTCVVVDIIPSDHSSTPPSLSPKKNQNKLRSLLFGRRSHSSVGKLGNKSASFDSVEELFEEGSAMLDERLGRNFPSKANSSPSRCAICQVDQAPFEDLVTDNGGGCCSAPSTPWVGPYLCSDCRKKKDAMEGKRSSRSTACR
What are the official names of this protein?
Probable protein phosphatase 2C 33, OsPP2C33.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: YCF4_SYNSC
Sequence: MSAAVLEQPVLGSRRLSNFLVASAVTIGGVGFLLASLSSYLGRDLVPIGHPAALVFVPQGLVMGLYSLAAALLATYLWYVIAVNVGGGSNRFDKDAGVVTISRRGFRKPVLVEIPLKDVKAVKVEVRDGFNARRRVALRIQGRRDMPLTRVGEPLPLAQLEKDGAELARFLGVNLEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RUTB_ECOSM
Sequence: MMTTLTARPEAITFDPQQTALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDAQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: CYSB_KLEPN
Sequence: MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDELGIQIFARSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYVATTHTQARYALPGVIKGFIERYPRVSLHMHQGSPTQIAEAVSKGNADFAIATEALHLYDDLVMLPCYHWNRSIVVTPEHPLATKGSVSIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGVGVIASMAVDPVSDPDLVKLDANGIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDTAVALRSNEDIEAMFKDIKLPEK
What is the function of this protein?
This protein is a positive regulator of gene expression for the cysteine regulon.  The inducer for CysB is N-acetylserine.  Thiosulfate and sulfide act as anti-inducers.
What are the official names of this protein?
HTH-type transcriptional regulator CysB, Cys regulon transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN148_RAT
Sequence: MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQESVLQDRSLPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQTDTHERLPQGLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINEDGSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHEKIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRMCHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKPEKKSSGMDKESVLDKSDTKKDRNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVLKKINSKRSLKQPLEQSQTISPLSTYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNLQEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASVIDENTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTEVTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLNSPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGDSQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGSRAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG
What is the function of this protein?
Involved in transcriptional regulation.  Represses the transcription of a number of genes including gastrin, stromelysin and enolase.  Binds to the G-rich box in the enhancer region of these genes.
What are the official names of this protein?
Zinc finger protein 148, Transcription factor ZBP-89, Zinc finger DNA-binding protein 89.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HEMH_ALIF1
Sequence: MNNKKTGVLLVNLGTPTAPTAAAVKQFLSEFLHDKRVVDMNRFIWCPLLHGVILPIRAPKVAKLYESVWMEEGSPLLVYSQRQVKALEARLSMPVALGMTYGEPRIKSGIESLEQQGCDEIIILPLYPQYSRTTTAAVFDQIAKQYKTTPVLPNFTMIHNYHDHPLYIKALANSVRQSWERNGKGDYVLCSYHGIPQRFVDNGDIYAAHCERTTELLAQELGLTSEQIGMSYQSRFGREEWLKPYTSETLKALAPKGIKSLDIISPAFSSDCLETLEELSEECKEIFMESGGQKYTFIPCLNDDELHIEMMADIVSSKIFNK
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPH6_BOVIN
Sequence: MRVAALISGGKDSCYNMMQCVAAGHQIVALANLRPAENQVGSDELDSYMYQTVGHHAIDLYAEAMALPLYRRTIRGKSVDTGPVYTKCEGDEVEDLYELLKLVKEKEEVEGISVGAILSDYQRVRVENVCKRLNLQPLAYLWQRNQEDLLQEMISSNIQAIIIKVAALGLDPDKHLGKPLDQMEPYLLELSKKYGVHVCGEGGEYETFTLDCPLFKKKIIVDSSEVVTHSADAFAPVAYLRFLELHLEDKVSPVPDNCRTSNDIHNS
What is the function of this protein?
Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.  Diphthamide biosynthesis consists in the conversion of an L-histidine residue in the translation elongation factor eEF-2 (EEF2) to diphthamide (By similarity).
What are the official names of this protein?
Diphthine--ammonia ligase, ATP-binding domain-containing protein 4, Diphthamide synthase, Diphthamide synthetase, Protein DPH6 homolog.
What is the protein family that this protein belongs to?
Belongs to the Diphthine--ammonia ligase family.
Protein: CCD82_HUMAN
Sequence: MIHVRRHETRRNSKSHVPEQKSRVDWRRTKRSSISQLLDSDEELDSEEFDSDEELDSDESFENDEELDSNKGPDCNKTPGSERELNLSKIQSEGNDSKCLINSGNGSTYEEETNKIKHRNIDLQDQEKHLSQEDNDLNKQTGQIIEDDQEKHLSQEDNDLNKQTGQIIEDDLEEEDIKRGKRKRLSSVMCDSDESDDSDILVRKVGVKRPRRVVEDEGSSVEMEQKTPEKTLAAQKREKLQKLKELSKQRSRQRRSSGRDFEDSEKESCPSSDEVDEEEEEDNYESDEDGDDYIIDDFVVQDEEGDEENKNQQGEKLTTSQLKLVKQNSLYSFSDHYTHFERVVKALLINALDESFLGTLYDGTRQKSYAKDMLTSLHYLDNRFVQPRLESLVSRSRWKEQYKERVENYSNVSIHLKNPENCSCQACGLHRYCKYSVHLSGELYNTRTMQIDNFMSHDKQVFTVGRICASRTRIYHKLKHFKFKLYQECCTIAMTEEVEDEQVKETVERIFRRSKENGWIKEKYGQLEEYLNFADYFQEEKFEL
What are the official names of this protein?
Coiled-coil domain-containing protein 82.
Protein: RL9_ECO27
Sequence: MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GLGA_MAGSA
Sequence: MRVLFASSEVFPLVKTGGLADVSGALPAALAAAGEDVRILLPGYPDAIKASGAKKAVGSLGDPFGLGAEATLLSGKLPGSGVPVWLVDCPALFERAGGPYQDPQGRDWPDNALRFALLSWTAAHLCTENSPVKWRPQVLHANDWQTGLAPAYLHAWSPAQRPATVFTIHNIAYQGQFPRDLVPRLGFPPEMYAMDGFEYYDTLSFLKSGLFYSDRITTVSPRYAKEIQTPAFGCGMEGLLAHRAADLTGILNGADYEVWNPAADTHLDHAFTPGDAAGKACNKAALQAELGLSQAPDAPLMVIVSRLNDHKGMDLVLAALPNILKMGAQVAVVGTGDRPLEDGFRAAAAAHPTQVAARIGYSEPLAHRMMAGGDMLLMPSRFEPCGLTQFYAFRYGTVPVAHATGGLADTLVDTGYDTLMTGKANGFVFEHSNVGAFQWAVERAVGLYAKKDQWTRIVKACNAQDFGWGRSAGLYRDLYKSLTGNGGGKGKKKA
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: Y907_ACIAC
Sequence: MPADSAPMNLTHHFLIAMPGLEDESFARSVVYLCEHSERGALGLIINKPSDLSLKGLFDKVDLSLRREDLSLEPVFRGGPVQTERGFVLHEAMGPSSGKQAAGEGGAQAEGEGAEESAYASTMSIPGGLEMTTSKDVLEALSTGAGPRRVLVTLGYSSWGEGQLESELAENSWLTVGADLSVIFDTPVGQRYDRALALLGLQSWMLSPEAGHA
What are the official names of this protein?
UPF0301 protein Aave_0907.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: LEUD_ECOLC
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RRF_PROM4
Sequence: MITKELEQNMRKSVEAAQRNFNTIRTGRANTSLLDRLTVEYYGADTPLKSLATISTPDSQTISIQPFDLSSLVLIEKSIAMSDLGFTPNNDGKIIRINIPPLTEERRKEFCKLASKYAEEGKVALRNIRRDAIERIKKSEKESEISEDQSRDEQDNVQKLTDRFITEIEKNLSDKEQEILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_STRM5
Sequence: MSMTDPIADLLVRIKNAAAVGKQTVKAPSSKIKVAIAQVLKDEGYITDLRVTALENNKSELEIVLKYFEGKPVIATLKRFSRSGLRQYRGKSELPKVMNGLGISIISTSKGIMTDAQARQLGVGGEVLCFVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: FEOC_YERPB
Sequence: MASLLQLRDAIALNGSAEASQLSRQLAIPLPLVNAMLEKLTAMGKIERIELDHSGCLTGSCKSCPEGHQHCNTVIYQLKEPHAHQ
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: POK25_HUMAN
Sequence: NKSKKRRNRVSFLGAATVEPPKPIPLTWKTEKPVWVNQWPLPKQKLEALHLLANEQLEKGHIEPSFSPWNSPVFVIQKKSGKWRMLTDLRAVNAVIQPMGPLQPGLPSPAMIPKDWPLIIIDLKDCFFTIPLAEQDCEKFAFTIPAINNKEPATRFQWKVLPQGMLNSPTICQTFVGRALQPVREKFSDCYIIHYIDDILCAAETKDKLIDCYTFLQAEVANAGLAIASDKIQTSTPFHYLGMQIENRKIKPQKIEIRKDTLKALNDFQKLLGDINWIRPTLGIPTYAMSNLFSILRGDSDLNSKRMLTPEATKEIKLVEEKIQSAQINRIDPLAPLQLLIFATAHSPTGIIIQNTDLVEWSFLPHSTVKTFTLYLDQIATLIGQTRLRIIKLCGNDPDKIVVPLTKEQVRQAFINSGAWQIGLANFVGIIDNHYPKTKIFQFLKLTTWILPKITRREPLENALTVFTDGSSNGKAAYTGPKERVIKTPYQSAQRAELVAVITVLQDFDINIISDSAYVVQATRDVETALIKYSMDDQLNQLFNLLQQTVRKRNFPFYITHIRAHTNLPGPLTKANKQADLLVSSALIKAQELHALTHVNAAGLKNKFDVTWKLAKDIVQHCTQCQVLHLPTQEAGVNPRGLCPNALWQMDVTHVPSFGRLSYVHVTVDTYSHFIWATCHTGESTSHVKKHLLSCFAVMGVPEKIKTDNGPGYCSKAFQKFLSQWKISHTTGIPYNSQGQAIVERTNRTLKTQLVKQKEGGDSKECTTPQMQLNLALYTLNFLNIYRNQTTTSAEQHLTGKKNSPHEGKLIWWKDNKNKTWEIGKVITWGRGFACVSPGENQLPVWIPTRHLKFYNEPIRDAKKSTSAETETPQSSTVDSQDEQNGDVRRTDEVAIHQEGRAANLGTTKEADAVSYKISREHKGDTNPREYAACSLDDCINGGKSPYACRSSCS
What is the function of this protein?
Early post-infection, the reverse transcriptase converts the viral RNA genome into double-stranded viral DNA.  The RNase H domain of the reverse transcriptase performs two functions.  It degrades the RNA template and specifically removes the RNA primer from the RNA/DNA hybrid.  Following nuclear import, the integrase catalyzes the insertion of the linear, double-stranded viral DNA into the host cell chromosome.  Endogenous Pol proteins may have kept, lost or modified their original function during evolution (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 25 Pol protein, HERV-K_11q22.1 provirus ancestral Pol protein.
What is the protein family that this protein belongs to?
Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.
Protein: KUNI_ORNKA
Sequence: MLFYVVITLVAGTVSGLNVRCNNPHTANCENGAKLESYFREGETCVGSPACPGEGYATKEDCQKACFPGGGDHSTNVDSSCFGQPPTSCETGAEVTYYDSGSRTCKVLQHGCPSSENAFDSEIECQVACGVSME
What is the function of this protein?
Tick salivary thrombin inhibitor that plays an important part in the anti-hemostatic strategy of ticks.  Inhibits thrombin-induced platelet aggregation, but has no effect on ADP- or collagen-induced aggregation (PubMed:10502470).  Is a competitive, slow-, tight-binding inhibitor of thrombin (Ki=4. 89 pM) (PubMed:10502470).  It requires thrombin fibrinogen-binding exosite for optimal inhibition, as its affinity for thrombin lacking the exosite is much lower (Ki=22. 3 nM) (PubMed:10502470).  Its N-terminal amino acid residues may bind inside the active site cleft of thrombin, while its C-terminal domain may interact with the basic fibrinogen recognition exosite of thrombin (PubMed:12044499).  It does not inhibit plasmin, factor Xa (F10), and trypsin (PubMed:10502470).
What are the official names of this protein?
Thrombin inhibitor savignin.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Secreted.
Protein: SECA1_STAA3
Sequence: MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: RSA3_KLULA
Sequence: MSEGHIAAISKTNKRKNRRKKRRTQDVSDSSSDSSSDSENSSVEDNDTKLETVEKAASDVEDVTLSDIDMDKEEDEAALDDKKASRKEGSVLSSETVDKLNKVGLTTSDLTGNNGIHLGNIDLNKMSATLDESSNKLLENNKDKNGLKNQYLSMLFESYGDDMNELRNAPDFTSKTLVMLANVLKDGGDMFDLETLKTIVEDK
What is the function of this protein?
Required for efficient biogenesis of the 60S ribosomal subunit.
What are the official names of this protein?
Ribosome assembly protein 3.
What is the protein family that this protein belongs to?
Belongs to the RSA3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: EMTA_SALEP
Sequence: MKLRWFAFLVVILAGCSSKQDYRNPPWNAEVPVKRAMQWMPISEKAGAAWGVDPHLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWRGEPTTSELKNPERNISMGAAYLSILENGPLAGIKDPQVMQYALVVSYANGAGALLRTFSSDRKKAIEKINDLDADEFFEHVVDNHPAPQAPRYIWKLQQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SYN_THET8
Sequence: MRVFIDEIARHVDQEVELRGWLYQRRSKGKIHFLILRDGTGFLQATVVQGEVPEAVFREADHLPQETALRVWGRVREDRRAPGGFELAVRDLQVVSRPQGEYPIGPKEHGIDFLMDHRHLWLRHRRPFAVMRIRDELERAIHEFFGERGFLRFDAPILTPSAVEGTTELFEVELFDGEKAYLSQSGQLYAEAGALAFAKVYTFGPTFRAERSKTRRHLLEFWMVEPEVAFMTHEENMALQEELVSFLVARVLERRSRELEMLGRDPKALEPAAEGHYPRLTYKEAVALVNRIAQEDPEVPPLPYGEDFGAPHEAALSRRFDRPVFVERYPARIKAFYMEPDPEDPELVLNDDLLAPEGYGEIIGGSQRIHDLELLRRKIQEFGLPEEVYDWYLDLRRFGSVPHSGFGLGLERTVAWICGLAHVREAIPFPRMYTRMRP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.