PharMolix/UniProtQA huggingface dataset:
Protein: YL12B_YEAST
Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQPASVPPPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNLSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLGQELTESTVNHTNHSDDELPGHLLLDSGASRTLIRSAHHIHSASSNPDINVVDAQKRNIPINAIGDLQFHFQDNTKTSIKVLHTPNIAYDLLSLNELAAVDITACFTKNVLERSDGTVLAPIVKYGDFYWVSKKYLLPSNISVPTINNVHTSESTRKYPYPFIHRMLAHANAPTIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNSYEPFQYLHTDIFGPVHNLPNSAPSYFISFTDETTKFRWVYPLHDRREDSILDVFTTILAFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRTLLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLPFGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKESRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQPRNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQISNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPISSTGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEESIIADLPLPDLPPESPTEFPDPFKELPPINSRQTNSSLGGIGDSNAYTTINSKKRSLEDNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYNKDIKEKEKYIEAYHKEVNQLLKMKTWDTDEYYDRKEIDPKRVINSMFIFNKKRDGTHKARFVARGDIQHPDTYDSGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIKEELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVFKNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEIKYQRGKYMKLGMENSLTEKIPKLNVPLNPKGRKLSAPGQPGLYIDQDELEIDEDEYKEKVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDKQLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTSTTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRFFGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH
What is the function of this protein?
Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane.  Once in the nucleus, integrase performs the integration of the dsDNA into the host genome (By similarity).
What are the official names of this protein?
Transposon Ty1-LR2 Gag-Pol polyprotein, Gag-Pol-p199, TY1A-TY1B, Transposon Ty1 TYA-TYB polyprotein, p190.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CA426_CONBU
Sequence: LVVLATTVVSFRSNRASDGRKIAVNKRRRELVVPPGKLRECCGRVGPMCPKCMCPPRRC
What are the official names of this protein?
Conotoxin Bu26.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYA_CHLPD
Sequence: MNSREIRQSFLDFFDRKGHTIVRSAPVIPLDDPTLLFTNAGMNQFKDVFLDKGTRPYVRAADTQKCIRASGKHNDLEDVGRDTYHHTFFEMLGNWSFGDYYKKEAISWAWELLTSVWHLPKERLYATVYYDDEESYLLWQEETDIPHDHIIKFDEKDNFWEMGETGPCGPCSEIHIDLTEDGSGKPLVNAGDYRVIELWNLVFIQYNRQADGRLEPLPQKHVDTGMGFERVCAVMQGKASNYDTDVFRPLFDRITEITGVSYNASLDDPSDIAMRVLADHARTLTFALTDGAMPSNEGRGYVLRRILRRALRYSKTLGCSEPLLYRLVETLAASMGDVFPELRKQQQAVSRIIRAEEESFLATLDRGIEIFNELIAAVRSRGTTVVSGDDAFRLYDTFGFPLDLTRLMAAEAGFEVDEEGFDRCMKEQKTRARQDRRDKQHLKGDEGEWTWFSAERTSVFTGYHSLEELASITGVSIFSDRLLVVLDRTPFYAESGGQCGDRGWIETAAYRLRVSDTRKDGDMIVHLVTEVRDSVSDGAISPADLSFDEGKLACRASVDRSDRQGTERNHTATHLLHAALRRTLGQHVQQKGSFVSSERLRFDFSHFARLTSEELAIVESEVNEQIRSAEPVVKHQDIPYDEAIARGALAFFGDKYADRVRVVEIAGLSVELCGGTHVDSIGQIGLFKIVSESSVASGVRRIEALTGKAAEVLLWKEYRELQDIRQMLKLKADEEVIGRIAELADSKKELEKQLQVYRTEALSGILQRSLDAAESVGSIRFMTLRLEHVDQDSLRQAVLALREKDPASTGLLCTEEDGKVSLTAFAGERAVGEFGLDAGKLVREAAAFVRGGGGGKPEFATAGGKDPEGIQKAFDSFAASVREKVSAK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNTP_XYLFA
Sequence: MSPITILLIGIAMSTDAFAAAIGKGAAIGKPRLRDALYVAVIFGVIETATPIAGWLLGQIASHYIATFDHWIAFGLLSGLGIHMIVNGLKNNGNTCKDNADTHNRNSRWLPLAATALATSIDAAAIGISLAFLDIHISIVAAVIGLCTFTMVIFGVMLGRVLGTFVGNRAEIVGGIILIIVGSTILYEHLSNNG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NMT_YARLI
Sequence: MSADKFNEILKMFQQQMAMQDIPDREKAKKWEEYLFWKTQPVPKFDEDIDSEGPIEHKKLEDVRPTPYNLPAEYEWSDVDIENPEHIQEVYDLLYDNYVEDDDATFRFKYSASFLDWALKPPGWQKTWYPCVRVAATGKMVAFISAIPTSIQLRDNDLIKAVEINFLCVHKKLRSKRLAPVLIKEITRRVNQKDIWQALYTAGVVLPSPVSTCRYYHRPLNWTKLYEIGFSAIPPNQTAASMVARYTLPKEVPLKVRAMTKADVKAVHAILQNYLSAASEMSQHFSEEEVAHWFVDPISEDKNDDKIVYSYVVEEDGKVIDFFSFYKLDHTVLKEWATESNLRAAYGFYYATSSLSSAKARQDRVKELIGSAVILANNLGFEVYNELTLLDNPSHLDDLKFGCGDGYLNYYLFNYRAQPVHGGLDKQKQLEQLDGKGVGVIML
What is the function of this protein?
Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
What are the official names of this protein?
Glycylpeptide N-tetradecanoyltransferase, Myristoyl-CoA:protein N-myristoyltransferase, NMT, Peptide N-myristoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1C_PELHO
Sequence: MIIDTPEVQDINSFSRFESLQEIYGIVWMLVPILTLVVGITIGVLVIVWLEREISAGIQQRIGPEYAGPFGILQALADGTKLLLKENLLPSRGDSPLFSIGPSMAVISILLSYSVIPFSYRLVLADLNVGVFLWIAISSIAPIGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLTLCVLSISLLSNSSSTVDIIEAQSKYGFWGWNLWRQPIGFLIFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFAFFYITSYFNLLVSSLFVTILYLGGWNMSIPYIDFLPLFEINNVGGIFRTTTELFITLAKTFFFLFISITTRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PNP_ACTP2
Sequence: MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVTVVAKKEVKEGQDFFPLTVDYQERTYAAGRIPGGFFKREGRPSEGETLIARLIDRPVRPLFPEGFFNEIQVIATVVSVNPQISPDLVAMIGASAALSLSGVPFNGPIGAARVGFINDQFVLNPTTSEQKISRLDLVVAGTDKAVLMVESEADILSEEQMLSAVVFGHQQQQVVIENIKEFVKEAGKPRWDWVAPEPNTALINQVKALAEARIGDAYRITEKQARYEQIDAIKADVIAQLTAQDETVSEGAIIDIITALESSIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVATLGTERDAQIIDELTGEKSDRFLFHYNFPPYSVGETGRIGSPKRREIGHGRLAKRGVLAVMPTAEEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEEEKFVVLSDILGDEDHLGDMDFKVAGTREGVTALQMDIKIEGITPEIMQIALNQAKGARMHILSVMEQAIPAPRADISDFAPRIHTMKIDPKKIKDVIGKGGAVIRALTEETGTSIDIDDDGTVKIAATDNNAAKAVMARIEDIVAEVEVNAIYKGKVTRVVDFGAFVSILGGKEGLVHISQITNERVERVADYLSVGQEVTVKVVEIDRQNRIRLTMKDLNNDTPVAENVTEEAEVSSEQQAEI
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_RICRS
Sequence: MTKIVRSKYKASRRLGVSLWGDSKDAFNTRNYRPGQHGQNTMIKTSDYGLHLKAKQRLKCHYGRVTEKQFRNIFALAQKMKGNTGENFIGLLESRLDTVVYRMNIAPTIFAARQLVSHGHIKLNGKKADIASIRLKAGDVIEVKESVKQIPLIQESVSKQGQTTPGYLSFDVPSLTGKYLRVPALSDVPYPFEAEVHLVIELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: Y350_METJA
Sequence: MAKVRHGCRTERIELIIKINHLKRENLKLRNKIADYKRTLYLIRGKGCKLTEELLKIEIENCIKMIKFNEETIRDLKEKVEMIPNEQL
What are the official names of this protein?
Uncharacterized protein MJ0350.
Protein: TX704_LYCSI
Sequence: MKLIIFTGLALLLIVSLIDVEAQNEGACLPRGSVCTTNHASCCSKLSCDCYRRFEKGVEKGQKCWCIPTGLRYSKEKE
What are the official names of this protein?
U7-lycotoxin-Ls1e, Toxin-like structure LSTX-G4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 07 (U7-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NAKD2_MOUSE
Sequence: MTCYRGFLLGSCRRVAGGRAALRGSGSGADGRRHLGHGQPRELAGGGSPADGGFRPSRVVVVAKTTRYEFEQQRYRYAELSEEDLKQLLALKGSSYSGLLERHHIHTKNVEHIIDSLRDEGIEVRLVKRREYDEETVRWADAVIAAGGDGTMLLAASKVLDRLKPVIGVNTDPERSEGHLCLPVRYTHSFPEALRRFSRGEFRWLWRQRIRLYLEGTGINPTPVDLHEQQLSLNQHSRAFNIERAHDERSEASGPQLLPVRALNEVFIGESLSSRMPYCWAVAVDNLRRDIPNLKGLASYYEISVDDGPWEKQKSSGLNLCTGTGSKAWSFNINRVAAQAVEDVLHIARRQGNLTLPLNKDLVEKVTNEYNESLLYSPEEPKILFSIREPIANRVFSSSRQRCFSSKVCVRSRCWDACMVVDGGTSFEFNDGAIASMMINKEDELRTVILEQ
What is the function of this protein?
Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+).  Can use both ATP or inorganic polyphosphate as the phosphoryl donor (By similarity).
What are the official names of this protein?
NAD kinase 2, mitochondrial, Mitochondrial NAD kinase, NAD kinase domain-containing protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUOI_YERPN
Sequence: MTLKELVVGFGTQVRSLWMIGLHAFHKRETLMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAEQKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKQKGEAENEAKPIDVKGLMP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LUXS_LACP3
Sequence: MAKVESFTLDHTAVKAPYVRLITTEHGAKGDVISNYDLRLVQPNTAAIDTAGLHTIEHLLASLLRDRMDGVIDCSPFGCRTGFHLITWGEHSTTEVAKALKSSLEAIANDITWDDVPGVDIKSCGNYKDHSLFSAKEWAKLILSRGISNDPYTRQVV
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: HBB1_ARCGL
Sequence: WSKIDIDVCGPLALQRCLIVYPWTQRYFGSFGDLSTVAAIMGNPKVAQHGVVALTGLRTALDHMDEIKSTYAALSVLHSEKLHVDPDNFRLLCECLTIVIAGKMGKKLSPDMQAAWQKYLCAVVSALGRQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-1, Beta-1-globin, Hemoglobin beta-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GLYA_METAC
Sequence: MSYIEKIDPDMFEAIQKEADRQEHKLNLIASENYASRAVMEAQGSIMTNKYAEGYSGKRYYGGCDFVDIAENLAIARAKEIFGAKYVNVQPHSGSGANMAVYFSVLQPGDTIMSMDLSHGGHLSHGSPVSFSGKLYNIVPYGVSKETEALDYDELMKMAKECKPKMIVCGASAYPRVIDFKKFREIADEVGAYLLADIAHIAGLVVSGVHPSPVPYADFVTTTTHKTLRGPRGGMIISKTEELAMGVNKAVFPGIQGGPLMHVIAAKAVAFKEAMDEKFRQDQAQTVKNAKVLCACLKEKGFDIVSGGTDNHLMLVNLNNMNITGKDAEAAMSKAGIIANKNTVPFETRSPFITSGVRLGTPACTTRGMKEKEMELIADYIETAIKNAGNDALLSEVSAKVRDLCSRFPVYS
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_STAAB
Sequence: MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCKNCGSYNGEEVAAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RNC_BACC1
Sequence: MPYRKYREKKYETKYREAFKVFQEKIGITFTDEKLLIQAFTHSSYVNEHRKKPHEDNERLEFLGDAVLELTVSQYLFQKYPTMSEGELTKLRAAIVCEPSLVRFANELSFGSLVLLGKGEEMTGGRERPALLADVFEAFIGALYLDQGLETVWGFLKEIVYPKINEGAFSHVMDYKSQLQELIQRDGSGNIEYQILQEKGPAHNREFVSRVTLNNVALGLGSGKSKKEAEQQAAAEALKKLKEQL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_BACAH
Sequence: MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKTVPADVAEKIEKRYTVSEHKRQVPASMFDDWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: HIS4_BUCA5
Sequence: MIIPAFDLINGRTVRLYQGDYSNQKNYNVNLFNSLEVYKSKGIEIVHLVDLDGAKNSANRQIELFKKIVSHTTVPVQVGGGIRTTKDISTLLDLGVKRVVIGSSIVSNKKQVKQWLNFYGPDAIVLALDVHVDGSNKKEISIDGWQKKTNFILEEIIEYFLSSGLKHVLCTDISRDGTLLGPNFKLYKEICSNFKNINFQASGGVASLQDIIFLKKTGVKSIIIGRSLLEKKFTIEEAVKCWQRES
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPH2_MYXVL
Sequence: MENHLPNIFYFPNCVTAFPYRYTQKELDDMKPVDRERFKYAVFPLIKHRWCRAYVVRDNHTFKLNVETSKRLRRVAYPTLVPLVGVNAALREYVMEDGTKISFECYSYLICKRTTSLHDVDDSTIRGLVEGGNQLNIFTNSVGSVTNTVGIFGNPNPFAKVPLKSLHPSMQCKIFTSWARRVPVVLTGDTGVGKTSQVPKLLLWFNYLFGGFTDLSTLTFEVQEKPIVLSLPRVALVKLHSETLLTSLGFEEIHGSPVSLKFGNMQERFVNTRFSRYGIVFSTHKITLNTLFKYSTVILDEVHEHDQTGDIIIAVCRKYIRKLDSLFLMTATLEDDRRRIEEFFAESVFVHIPGGTLFSISEAYVKNSNDPLNRFMYIEEEKRNLANAIKTYTPPKQSSGIVFVSTVSQCEAYKQYLSERLPYKFYIIHGKVQNINDVLSDIYDNDGVSIIISTPYLESSVTVRNATHVYDTGRVYIPSPYGGCESFISKSMRDQRKGRVGRVNPGMYVYFYNVSELRPIKRIDFEFLHNYVLYAKVFDLQLPEDLFVKPTNVTRLHDVIEYIRSFDISDDVWTRLLSSYYIHILEYAKVYARGGSGALALDSFERTGNLTDDALDAIKSLNMRAKILSHKKASAHTYALRCKLLFGVYAGKVFTVYHKRPLTGYITMIAEHSFIPDY
What is the function of this protein?
NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase.  Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm.  Required for replication and propagation of viral particles.
What are the official names of this protein?
RNA helicase NPH-II, Nucleoside triphosphatase II, NTPase II, Nucleoside triphosphate phosphohydrolase II, NPH II, RNA helicase m44R.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: FABPL_CHAVI
Sequence: MKAIGLPDDLIQKGKDIKGVSEVVQEGKHFKVTITTGSKMETMTGEKVKTVVRMEGDNKLVTTFKGIKSVTEFNGDTVXNXMTLGXIVFKRVSKR
What is the function of this protein?
This protein binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm; it may be involved in intracellular lipid transport.
What are the official names of this protein?
Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_COXBR
Sequence: MDEKIETRLIGATVQSNEPDLERSIRPKRLSDYIGQAAVREQMDIFIRAATNRREALDHVLIFGPPGLGKTTLAHIIAHEMQAGLKQTSGPVLEKAGDLAALLTNLEPHDVLFIDEIHRLNPAIEEVLYPALEDFQLDIIIGEGPSARSIKLDLPPFTLVGATTRAGLLTSPLRDRFGIVQRLEFYRIPDLIHIVKRAAHILNVVIDENGAGEIARRSRGTPRIANRLLRRVRDFAEVRANGMINESIAKEALDLLNVDIRGLDVMDRKLLETIIKKFQGGPVGIESLAAAISEERGTIEDVIEPYLIQEGFILRTPRGRIATELTYQHFKLPLPTQSTLQENFDLLGKVE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ATPB_KLULA
Sequence: MVLPRFYAASSRAALQAARRAVPFTGVRGYAAAASSQGKVRAVIGAIVDVQFEQGQLPAILNALEIDTPEGKLVLEVAQHLGENTVRTIAMDGTEGLVRGENVSDTGAPISVPVGRETLGRIINVIGEPIDERGPINSKMRKPIHADPPLFVEQSTAAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFTGVGERTREGNDLYREMKETGVINLEGDSKVALVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGLLQERITTTKKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDAAVVGQEHYDVATQVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFAVAEVFTGIPGRLVRLKDTISSFKAVLDGKYDHLPENAFYMVGGIEDVVAKAEKLAAEAN
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Peripheral membrane protein.
Protein: DPO4_YERPP
Sequence: MRKIIHVDMDCFFAAVEMRDDPRLRDIPLAIGGSKERRGVISTANYPARRYGVRSAMPTAMAFKLCPQLTLLPGRMAAYKEASQHIREIFARYTPLIEPLSLDEAYLDVSDSLACGGSATLIAQEIRQSIASELNLTASAGIAPIKFLAKIASELNKPNGQYVITPNQIQPFLQDLPLSKIPGVGAVTAKRLQALGLVTCGDIQKYPLAELLKHFGKFGRVLWERSHGIDEREISPDRLRKSVGVEKTLAEDIYDWESCEALIEELYLELETRLRKVKPSLHIARQGVKLKFHDFQQTTQEHTWPVLNKVDLLEIAHAAWHERRAERGVRLVGLHVTLLDPQLERQLLLDWG
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORFX2_PARBF
Sequence: MSKKPLDFLRIYDWHKTEAMNKISKLDFERIIPKHFSKEIKNKHLSVKITGNWKIWKLTDEGEGQYPIFKCIVEDGFLKIKNECGNKKYSLDNAWIKICTKIKYDNENGKDIYSIDEKNLTLYSVNNSFNSKYKNNIVDAFLDNLLIACIEDNIKDLNKFFKLYKVKTAIKEDLSLLGWDTGYSTSFTHVNKTIENQQNYPKQFKYESEGPYNIDISGEFDSWRLTTGSDGQNVNFICPIKNGEFNFLGTEYKFSQGEQVNIQLKLKYLNIEEPTFEDSTSLNDGNQVDLIVKTDEDENENPPVTIIKVVLLGEIDAIGKMLLEGTFREWFNENIDAFKQIFSSFLLEDTSKNPDFQWLKPTKAYYGVASAEPIDGKPDLDSSVFSVMSMVEDNKNDKPSHTVDGRILDAVNNESAFGIRTPLFVKKWLIAGLEMMQIGKLEDFDLINNGMGFINNKKLLFGTFENADGEDVPAYVEKDNFRLEITNNQLKIEITDIYWQQSRRLTGHVMYSQYFDLELRSGTDITGAEYKNILIPVENSEPTLVVNISQDEFDIWGDIVGEIVGGIVVGIVTGYLGSILGKGVGKYLEKFLTKTSGGRWVLKMNKEMYDYLNNLFKGDRRVFNEVAIDEIELISTLGTSQAISTIANTPTNFASKIWVNKSKFIGGLIGGSVGSVIPSVIIKSIDAWDKQNYSVLPSINAFVASSVGSVKWPDTSEFKIESAELNGIFLLGGKLERYEK
What is the function of this protein?
Expression of the ptox operon (ntnh-orfX1-orfX2-orfX3-pmp1) in B. thuringiensis kills Anopheles but not Aedes mosquito 3rd instar larvae.  The ntnh-pmp1 construct is about half as toxic.
What are the official names of this protein?
Protein OrfX2.
What is the protein family that this protein belongs to?
Belongs to the TULIP P47 family.
Protein: Y2420_SHESM
Sequence: MAFDKKLLDIVACPVCKGKLEYDKTTQQLICKADKLAYPITDGIPVLLENRAVPLNEAV
What are the official names of this protein?
UPF0434 protein Shewmr4_2420.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.