PharMolix/UniProtQA huggingface dataset:
Protein: KPRA_RAT
Sequence: MNAARTGYRVFSANSTAACTELAKRITERLGAELGKSVVYQETNGETRVEIKESVRGQDIFIIQTIPRDVNTAVMELLIMAYALKTACARNIIGVIPYFPYSKQSKMRKRGSIVCKLLASMLAKAGLTHIITMDLHQKEIQGFFCFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQSYAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGDVGGRIAIIVDDIIDDVESFVAAAETLKERGAYKIYVMATHGILSAEAPRLIEESPIDEVVVTNTVPHELQKLQCPKIKTVDISLILSEAIRRIHNGESMAYLFRNITVDD
What is the function of this protein?
Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis.
What are the official names of this protein?
Phosphoribosyl pyrophosphate synthase-associated protein 1, PRPP synthase-associated protein 1, 39 kDa phosphoribosypyrophosphate synthase-associated protein, PAP39.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
Protein: RRF_METSB
Sequence: MSAEFDLADIKRRMQGAIATLKHELGGLRTGRASASLIEPVNVEAYGQTMPLNQVATISVPEPRMLSVQVWDKGMVGAVDKAIRNANLGLSPTVEGQVLRIRIPELNEQRRKEMAKVAHKYAEDARVAIRHVRRDGIDVLKRLLKDKEISEDDEKRHESEVQKATDQCVADVDSALVAKEREIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M1_I76A6
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVATTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: Y108_HERAR
Sequence: MFELKTVALFVVTAIAEIVGCYLPYLWLRQSGSIWLLLPAALSLALFAWLLSLHPEASGRVYAAYGGIYVAVALGWLWLVDGIKPTNWDVAGVVFTFIGMGIIMFAPRA
What are the official names of this protein?
UPF0060 membrane protein HEAR0108.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NAPA_ALIF1
Sequence: MKMTRRAFVKANAAASAAAVAGVTLPASATNLIVSSDQTKIKWDKAPCRFCGTGCSVLVGTQNGRVVATQGDPEAPVNKGLNCIKGYFLSKIMYGKDRVQTPMLRMKDGQYNKDGDFAPVSWDVALDTMAEKWKAALKKHGPTGVGMFGSGQWTVMEGYAAVKLMKAGFRSNNIDPNARHCMASAVGAFMRTFGIDEPMGCYDDFENADSFVLWGSNMAEMHPVLWTRISDRRLSHPHVKVNVLSTYYHRSFELADKGYIFEPQSDLAIANFIANYIIQNNAVNWDFVNKHTNFKQATTDIGYGLRDDDPLQMEAANPNSGAMSSISFEEYKKSVAPYTAQKASEMSGVSEEDLITLAKQYADPKTKVMSLWTMGMNQHTRGVWMNSLVYNIHLLTGKIATPGNSPFSLTGQPSACGTAREVGTFSHRLPADMVVANPKHRAISEKIWKLPEGTLNGKPGAHAVVQDRMLKDGKINAYWVMCNNNMQAGPNINTERLPGYRNPENFIVCSDPYPTATAQAADLILPTAMWVEKEGAYGNAERRTQAWYQQVQAKGEAKSDLWQIMEFSKRFKVEEVWGEELVAKAPEYRGKTMYDILFKNGQVDAFPLSEAQELNDDAKAQGFYVQKGLFEEYASFGRGHGHDLAPYDTYHTVRGLRWPVVDGKETLWRFKEGSDPYAKKGSDWDFYGKPDGKALIISAPYEAPPEVPNDEFDMWLCTGRVLEHWHTGTMTRRVPELYKAVPDALCYIHPADAKKRNLRRGDEVLISNKRGEVRVRVETRGRNRPPEGLVFVPFFDARILINKLILDATDPLSKQTDFKKCPVKITKIA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: PUR7_ECO45
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: TRPC_PROM2
Sequence: MEIRRRPPNPTVRVENLEYAVPHREAQAKNILEEIVWHKDIEIKNFKKIVSLEDLIKKIENLPAPKDFYKNILESKIKPGVIAEIKKASPSKGVIRKDFNPKDIAICYEGLGASCISVLTDKRFFQGSYEILETVRKSTNLPLLCKDFIISAYQIYKARVSGADAILLIAAILSDDDLIYLKKIADNLKMSVLVEVHNDNELERILKLKSFNLIGINNRDLKTFKTDLKTSIELMNVYADIFSKQNILPISESGINCAKDLESLRSIGIKGVLIGETFMRESDIEESFNKLFYSI
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: FBW1A_HUMAN
Sequence: MDPAEAVLQEKALKFMCSMPRSLWLGCSSLADSMPSLRCLYNPGTGALTAFQNSSEREDCNNGEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLASTAMKTENCVAKTKLANGTSSMIVPKQRKLSASYEKEKELCVKYFEQWSESDQVEFVEHLISQMCHYQHGHINSYLKPMLQRDFITALPARGLDHIAENILSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPNSFYRALYPKIIQDIETIESNWRCGRHSLQRIHCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNTLECKRILTGHTGSVLCLQYDERVIITGSSDSTVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVTCSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSRTYTYISR
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Recognizes and binds to phosphorylated target proteins (PubMed:10066435, PubMed:10497169, PubMed:10644755, PubMed:10835356, PubMed:11238952, PubMed:11359933, PubMed:11994270, PubMed:12791267, PubMed:12902344, PubMed:14603323, PubMed:14681206, PubMed:14988407, PubMed:15448698, PubMed:15917222, PubMed:16371461, PubMed:25503564, PubMed:25704143, PubMed:9859996, PubMed:22087322).  SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling (PubMed:12077367, PubMed:12820959).  SCF(BTRC) mediates the ubiquitination of phosphorylated NFKB1, ATF4, CDC25A, DLG1, FBXO5, PER1, SMAD3, SMAD4, SNAI1 and probably NFKB2 (PubMed:10835356, PubMed:11238952, PubMed:14681206, PubMed:14603323).  SCF(BTRC) mediates the ubiquitination of NFKBIA, NFKBIB and NFKBIE; the degradation frees the associated NFKB1 to translocate into the nucleus and to activate transcription (PubMed:10066435, PubMed:10497169, PubMed:10644755).  Ubiquitination of NFKBIA occurs at 'Lys-21' and 'Lys-22' (PubMed:10066435).  SCF(BTRC) mediates the ubiquitination of CEP68; this is required for centriole separation during mitosis (PubMed:25704143, PubMed:25503564).  SCF(BTRC) mediates the ubiquitination and subsequent degradation of nuclear NFE2L1 (By similarity).  Has an essential role in the control of the clock-dependent transcription via degradation of phosphorylated PER1 and PER2 (PubMed:15917222).  May be involved in ubiquitination and subsequent proteasomal degradation through a DBB1-CUL4 E3 ubiquitin-protein ligase.  Required for activation of NFKB-mediated transcription by IL1B, MAP3K14, MAP3K1, IKBKB and TNF.  Required for proteolytic processing of GLI3 (PubMed:16371461).  Mediates ubiquitination of REST, thereby leading to its proteasomal degradation (PubMed:21258371, PubMed:18354482).  SCF(BTRC) mediates the ubiquitination and subsequent proteasomal degradation of KLF4; thereby negatively regulating cell pluripotency maintenance and embryogenesis (By similarity).
What are the official names of this protein?
F-box/WD repeat-containing protein 1A, E3RSIkappaB, Epididymis tissue protein Li 2a, F-box and WD repeats protein beta-TrCP, pIkappaBalpha-E3 receptor subunit.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PEPT3_CAEEL
Sequence: MEEKSLLQKLRSYPPAVFFMLGNEFCERFSFYGMKTILFIYLITEHEFSPSKATFIYHLFTCIAYLTPLIGSIMADSVFGRFKVILYGSSIYVVGHVLLSLGAVPFLSYPIRSSLDFSGLFVIAFATGCIKPCVSAFAADQFTEDQKDLRSQFFSFFYFAINGGSLFAIIITPILRGRVQCFGNAHCFPLAFGVPGVLMLLALILFLMGWSMYKKHPPSKENVGSKVVAVIYTSLRKMVGGASRDKPVTHWLDHAAPEHSQKMIDSTRGLLNVAVIFCPLIFFWALFDQQGSTWVLQARRLDGRVGHFSILPEQIHAINPVCVLILVPIFEGWVYPALRKITRVTPLRKMAVGGLLTAFSFAIAGVLQLKVNETMEFPPSLGRIYLQRVGNESLISDFRYKSDGRLIGDGMLPKGRTELDAGIYTFNTGLKNESQEIDISTPNKGYVMAVFRLKDAVEVVKFDYKVEKTDNGATRVFVVTAREDADTLVYAINKKGKILSSCELKSGSYVDVIPGIISDPNVRLYWGPKNSCSGVDCPNTVTLNAQMGAVHVLHIHPSTTEGDFNLLVRPNSVSILWSLPQYIIITLGEVLLSVTGLEFAYSQAAPNMKSVLTAMWLLTVFAGNLIDMMISGTRLIPHPALEFFFYSTLMVIVMGVFILLAMQYTYVEDNDDEITITESEKKDVIALTEIESGTATSDKKE
What is the function of this protein?
Neuron-specific, H(+)-coupled oligopeptide transporter with broad specificity towards di- and tripeptides in a Na(+) and Cl(-)-independent manner.  Shows H(+) channel activity in the absence of peptide substrates.
What are the official names of this protein?
Peptide transporter 3, Oligopeptide transporter 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: REM3_ARATH
Sequence: MANHPLSSSRSNRPFFVRSLAGHTSNLIIPDEFFTAHLEGKTGLTKLKLTSDASDRIWDVRLNGRRFAGGWDDFSAAHCLRDDDVLVFRLDVKMVFHVTPSGRSFSQIRTSSSSGDYDSDDDDDEAGDDDSDSKNISLKKKSRFEAESSSSEKYCLLGLTASNLRLNRVSFTKHFSRANGLTKRCCMIDLMNLSGESWTLGLRHNKRTGQAFIRGRWRSFCHANELKPGSFYRFKLVRNGTRPLLQLCFKVIPQGNCSNSKANGKANVSEKYSREDGSASTKQNKFLTVTLKHYMIQSGQLRLRRSFVRENGIKEAEEIILVDKNGVEWPSYVSSSKQRREFYMAHGWIRFCEANKLKTGETFTLEFVRGEGTTPMLKFCSEAKIEQEEAPEERGTPLPKRARVSAEVGHSRRTQAPNKSSDDPKILQRKQPLQPCSFSDQAKKVKQSIVNILTGIKRFRSELELKERNLEAALLEIDALGDKVSEINKILK
What are the official names of this protein?
B3 domain-containing protein REM3, Protein REPRODUCTIVE MERISTEM 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNH_STUS1
Sequence: MSDDWVEIYTDGACKGNPGPGGWGALLIYKGVKRELWGGEPDTTNNRMELMAAIRALAELKRPCKVRLVTDSQYVMQGINDWMPNWKKRGWKTASKQPVKNADLWQQLDEQVNRHEVSWQWVRGHTGHPGNEQADLLANRGVVQAKRQPIV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
Protein: Y1868_PROA2
Sequence: MVRLKEKDGGVVFFVKAQPRSSRSAIIGEYDGKIKISLKAAPVDDAANVECCRFLAKSLGVASSRVRILSGHSSRIKRLTIDGMGAAEAATLFGEHLESVEFDL
What are the official names of this protein?
UPF0235 protein Paes_1868.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: SHDD_SEDHY
Sequence: MKCHRCGSDNVRKMVDSPVGDAWEVYVCEKCCYSWRSTENPVVMEKFKLDDNKIANMGVIPPIPPLKK
What is the function of this protein?
Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives under anaerobic conditions, however the precise biochemical function of ShdD in metabolism of phenolic acid is unknown.
What are the official names of this protein?
Protein ShdD, Phenolic acid decarboxylase subunit D, PAD.
Protein: HSCB_AZOVI
Sequence: MTSHFALFDLEPDFRLDQDRLAVRYRELVRRVHPDRFAGAPEREQRLALEEAARLNEAYQTLKSPSQRARYLLSLQGEELSQETTVQDPAFLMQQMELREELQELQDSADLAGVARFKRRLVQDQEQLNEGFAACWADPRRRDEAERLARRMQFLDKLFAEVRQLEERLDD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: UXAB_ECO27
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQYRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: RPPH_HAEI8
Sequence: MIDFDGYRPNVGIVICNRKGQVLWAKRCGQNSWQFPQGGINDNESAEQAMYRELHEEVGLQPKDVRLLYVSKHWLRYKLPKRLLRYDSKPMCIGQKQRWFLLQLVGDEKNINMKTTKSPEFDGWRWVSFWYPVRQVVSFKRDVYRKVMKEFASVLFTDNPPIFSASREANSQSNSANKKYSQTKYTKRHFYKSKGQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PEPA_SORUN
Sequence: MKWLLLLGLVALAEGLIHKVALVKKKSLRQSLWENGLLEDFLKTHSLNPASKYFPTEATTLSANQPLVNYMDMEYFGTISIGTPPQEFTVIFDTGSSNLWVPSIYCSSPACSNHNRFDPQKSSTFKPTSQTVSIAYGTGSMTGVLGYDTVQVAGIADTNQIFGLSQSEPGSFLYYSPFDGILGLAYPSISSSGATPVFDNMWNQGLVSQDLFSVYLSSNDQSGSVVMFGGIDSSYYTGSLNWVPLSSEGYWQITVDSITMNGQSIACNGGCQAIVDTGTSLLSGPTNAIANIQSKIGASQNSQGQMAVSCSSIKNLPDIVFTINGIQYPLPASAYILQSQEGCSSGFQGMDIPTSSGELWILGDVFIRQYFTVFDRANNQVGLAPVA
What is the function of this protein?
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
What are the official names of this protein?
Pepsin A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOZ_CHESB
Sequence: MARVTVEDCIDKVENRFDLVLLASHRARQISQGEQITIDRDNDKNPVVALREIADETLSPGDLKEALIHSLQKHVEVDEPEADLPQIASQAEETPDAELAPEENIAFDRMSEEELLAGIEGLVPPEKNDDF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SOXE_SULAC
Sequence: MKAQSSVLPVVVGILVVIIAVAVGVYVYNQYVMLSSPSASSSTGTSTGPSKISIPYSSSNKTVFLTIVVESSSNVNQFNFNGTSSGSLVIYIPAGSTVIVKFINQESLPHNLVLLQNSTPTPQSPEISSDGKIIDIVGATTSNYDVNGISGGASAEGVWGPISAGDYMLVCGILGHAASGMWAVLVASNNVTAPYAVID
What is the function of this protein?
The 4 redox proteins SoxE, SoxF, SoxG and SoxH probably form part of a membrane respiratory complex together with SoxM, a catalytic subunit of cytochrome oxidase.
What are the official names of this protein?
Sulfocyanin, Blue copper protein.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: MCTP8_ARATH
Sequence: MMSNLKLGVEVISARLKPREDYGGVNAYVELRFDDQKVITMTKIDDSSPVWNEKFFFNISDTEDLSNQFLDAYVYNKTSSITKSCLGKIRILGTAFLPYSEAVGLPYPLEKEKWSMFSSAAANGGELALKVFLTDNPSPKVPNLISTKKIPSKSRHKFHNIPTNESNHSPRGNQQSFQPQPPPPQSQTALPPPMMESSLYQAPRFGTPIPTTMGFNPNPPDYSIKETKPILGGGKRARSSDHDLVEPMEFLFIKIVKARNLPSMDLTGSLDPYIEVKLGNYTGKTKHFEKNQNPVWNEVFAFSKSNQQSNVLEVIVMDKDMVKDDFVGLIRFDLNQIPTRVAPDSPLAPEWYRVNNEKGGEIMLAVWFGTQADEAFSDATYSDALNAVNKSSLRSKVYHSPRLWYLRVNVIEAQDLVIVPDRTRLPNPYVKIRLNNQVVRTKPSHSLNPRWNEEFTLVAAEPFEDLIISIEDRVAPNREETLGEVHIPIGTIDKRIDDNRTVPNRWFSLKTENQRRVRFATTRLHLNVCLEGGYHVLDESTYYSSDFRPSMKELLSHKQPSFGVLELGILRIEGLNLSQEGKKETVDAYCVAKYGTKWVRTRTVTNCLNPRFNEQYTWEVYEPATVITIGVFDNNQINSGNGNKGDGKIGKIRVRISTLEAGRIYSHSYPLLVLRPSGLKKMGELHLAIRFSCSSMFQMLMQYWKPLLPKMHYARPLKVVQQEILRQHAVNLVAARLSRAEPPLRKEVVEYISDSNSHLWSMRKSRANLFRLSSVFSGLLGTGEWFQDICRWKKPVETTAIHIIFLVLVCSPEMILPVMSLCLFMLGVWNYRLRPRQPPHMDTRLSFADNIHPEELNEEFDTFPFSSQDPGIVKMRYERLRSIASRAQTVVGDIAGQGERVQALLSWRDPRATSIFMVLCLVSTVVLYVVPFKVFVLLAGLYIMRPPRFRGKTPPGPINFFRRLPAKTDCML
What is the function of this protein?
May function as a signaling molecule by regulating the trafficking of other regulators.
What are the official names of this protein?
Multiple C2 domain and transmembrane region protein 8.
What is the protein family that this protein belongs to?
Belongs to the MCTP family.
Protein: IPAB_SHIDY
Sequence: MHNVNTTTTGLSLAKILASTELGDNTIQAGNDAANKLFSLTIADLTANKNINTTNAHSTSNILIPELKAPKSLNASSQLTLLIGNLIQILGEKSLTALTNKITAWKSQQQARQQKNLEFSDKINTLLSETEGLTRDYEKQINKLKNADSKIKDLENKINQIQTRLSELDPDSPEKKKLSREEIQLTIKKDAAVKDRTLIEQKTLSIHSKLTDKSMQLEKEIDSFSAFSNTASAEQLSTQQKSLTGLASVTQLMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKAEELNRVMGCVGKILGALLTIVSVVAAAFSGGASLALADVGLALMVTDAIVQAATGNSFMEQALNPIMKAVIEPLIKLLSDAFTKMLEGLGVDSKKAKMIGSILGAIAGALVLVAAVVLVATVGKQAAAKLAENIGKIIGKTLTDLIPKFLKNFSSQLDDLITNAVARLNKFLGAAGDEVISKQIISTHLNQAVLLGESVNSATQAGGSVASAVFQNSASTNLADLTLSKYQVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQANRTDVAKAILQQTTA
What is the function of this protein?
Associated with the entry of the bacteria into colonic epithelial cells.
What are the official names of this protein?
Invasin IpaB, 62 kDa antigen.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted through a type-III system.
Protein: QUEA_JANMA
Sequence: MYSLSDFDFELPQELIAQTPLAERSASRLLQVLPEQMTDRNFAYIVDLLSPGDLLVFNDTRVLKARFFGIKETGGKVEVLVERVIDQRNVHAQIRASKSPAVGMRIRLADAFDVIVGERAGEFYELQFPDDVFELIEAHGRLPLPPYIEHAADAYDETRYQTVYAKTPGAVAAPTAGLHFDQALLDALTAKGVKLAYITLHVGAGTFQPVRNENLAEHNMHSEWYTISQQTVDLVKATQVAGGNIVAVGTTSMRALESASQSGSLQAGSADTRLFITPGYTFKTVTRLITNFHLPKSTLLMLVSAFAGYDTIRAAYQHAISQRYRFFSYGDAMFLTRMPPC
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNPH_DROME
Sequence: MEADLEVQSELEKDTIPIKIGIIGEANLDKPIYLAERMEYAVCTPFGKPSDVIIDGQIEGVNVCLLSRNGRNHDIMPSNINYRANVWAMRKMGCTHILVTNTFSSLRDTFQPGHLVVPNDVIDYTSRRAQTFYDGAVGSPLGVCHVPMNPTFCERTRQHLLSAAEELGFPTGSSGTVLTLEGPRYSTVAENNMFRKWGADLLSMTLCPEAILAKEAGIPYASLGLVTNMECWCAKQPNATTHEIIYIFKKQSENLQKVLITAIRNMAAEDWAEDILKAKILVCSNFANSK
What is the function of this protein?
Purine nucleoside phosphorylase involved in purine salvage.
What are the official names of this protein?
Purine nucleoside phosphorylase, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COAA_YERPA
Sequence: MTKREQSLATPYLQFDRTQWAALRDSVPLTLTEEEIVKLKGINEDLSLDEVAQIYLPLSRLLNFYISSNLRRQAVLEQFLGTDGQRIPYVIGIAGSVAVGKSTTARLLQALLSRWPEHRSVELITTDGFLHPNKVLNERGLMKKKGFPESYDMHNLVKFVSEVKSGADYVTAPVYSHLIYDVVPDGNKVIKQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQSWYINRFLKFRQGAFSNPDSYFHNYAKLPETEAIKIATQLWNEINGLNLKQNILPTRERASLIMTKSANHAVESVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ENTFA
Sequence: MAELKITLKRSVIGRPQNQRATVKALGLGKVNSTVTKPANEAIKGMVNTISHLVDVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SERC_PSEA7
Sequence: MSKRAFNFCAGPAALPDAVLQRAQAELLDWRGKGLSVMEMSHRSDDYVAIASKAEHDLRDLLDIPSDYKVLFLQGGASQQFAEIPLNLLPEDGVADYIDTGIWSKKAIEEARRYGRVNVAASAKEYDYFAIPGQNEWNLTKDAAYVHYASNETIGGLEFDWIPETGGVPLVTDMSSDILSRPLDVSRFGLIYAGAQKNIGPSGLVVVIVREDLLGRARSACPTMLNYKIAADNGSMYNTPATYSWYLSGLVFEWLKEQGGVTAMERRNRAKKDLLYKTIDASDFYTNPIQPSARSWMNVPFRLADERLDKPFLEGAEARGLLNLKGHRSVGGMRASIYNALGLDAVEALVAYMAEFEKERG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTI_PHOLL
Sequence: MQQFEWWHAAFLFLAVVLDILANILLKLSNGFRRPWMGILSLIAVLGAFSALAQAVKGIELSIAYALWGAFGIIATVAAGWIMFNQRLNYKGWGGIALLLLGMVMIKMA
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HYBF_PROVU
Sequence: MHEITLCQSAFEIIDSQAKLNNAQKVKSVWMEISALSCVEVSALEFCFDIVCRDTIAQGCQLHIEVIPAKAWCWDCHQVVTVSTFNAGCPACGSQNLRVENDDAMRIKQIEIE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HybF.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family. HybF subfamily.