PharMolix/UniProtQA huggingface dataset:
Protein: AP2A1_ARATH
Sequence: MTGMRGLSVFISDVRNCQNKEAERLRVDKELGNIRTCFKNEKVLTPYKKKKYVWKMLYIHMLGYDVDFGHMEAVSLISAPKYPEKQVGYIVTSCLLNENHDFLKLAINTVRNDIIGRNETFQCLALTLVGNIGGRDFAESLAPDVQKLLISSSCRPLVRKKAALCLLRLFRKNPDAVNVDGWADRMAQLLDERDLGVLTSSTSLLVALVSNNHEAYSSCLPKCVKILERLARNQDVPQEYTYYGIPSPWLQVKAMRALQYFPTIEDPSTRKALFEVLQRILMGTDVVKNVNKNNASHAVLFEALSLVMHLDAEKEMMSQCVALLGKFISVREPNIRYLGLENMTRMLMVTDVQDIIKKHQSQIITSLKDPDISIRRRALDLLYGMCDVSNAKDIVEELLQYLSTAEFSMREELSLKAAILAEKFAPDLSWYVDVILQLIDKAGDFVSDDIWFRVVQFVTNNEDLQPYAASKAREYLDKIAIHETMVKVSAYILGEYGHLLARQPGCSASELFSILHEKLPTISTPTIPILLSTYAKLLMHAQPPDPELQKKVWAVFKKYESCIDVEIQQRAVEYFELSKKGPAFMDVLAEMPKFPERQSSLIKKAENVEDTADQSAIKLRAQQQPSNAMVLADQQPVNGAPPPLKVPILSGSTDPESVARSLSHPNGTLSNIDPQTPSPDLLSDLLGPLAIEAPPGAVSNEQHGPVGAEGVPDEVDGSAIVPVEEQTNTVELIGNIAERFHALCLKDSGVLYEDPHIQIGIKAEWRGHHGRLVLFMGNKNTSPLTSVQALILPPAHLRLDLSPVPDTIPPRAQVQSPLEVMNIRPSRDVAVLDFSYKFGANVVSAKLRIPATLNKFLQPLQLTSEEFFPQWRAISGPPLKLQEVVRGVRPLALPEMANLFNSFHVTICPGLDPNPNNLVASTTFYSESTGAILCLARIETDPADRTQLRMTVGTGDPTLTFELKEFIKEQLITVPMGSRALVPAAGPAPPVAQPPSPAALADDPGAMLAGLL
What is the function of this protein?
Subunit of the adaptor protein complex 2 (AP-2).  Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways.  Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation.  AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.  The complex binds polyphosphoinositides (By similarity).
What are the official names of this protein?
AP-2 complex subunit alpha-1, Adaptor protein complex AP-2 subunit alpha-1, Adaptor-related protein complex 2 subunit alpha-1, Alpha-adaptin 1, Clathrin assembly protein complex 2 alpha large chain 1, At-a-Ad, At-alpha-Ad.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane.
Protein: GLMM_CHRVO
Sequence: MSRKYFGTDGVRGEVGKFPITPEFVMKLGYAAGRVLVNHDQDSRPTVLIGKDTRISGYMLEAALQAGFTAAGVNVLLTGPLPTPGIAYLTRALRLEAGVVISASHNPFQDNGIKFFAEGGNKLDDALELEIEAMLDQPMATNPSLELGRARRIDGAAERYIEFCKSTFPNELSLKGLKLVVDCANGATYHIAPKVFHELGAELVEIGCEPNGYNINDKVGATYPKTLQMAVLEHQADFGIALDGDGDRLIMVDAAGRVYDGDQLIYVIAKARAARGELKGGVVGTVMTNMAMELALQKQGVPFGRAKVGDRYVLEMLHADGWQVGGEASGHILCLDKHSTGDGIISSLQVLASLKQLGLSLAEICADWRPFPQTLINVRHNGCDWKAASAAPLAEAEAALQGRGRVVLRPSGTEPVVRVMVEADDKALADTWAKAIAAAIEKVSA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CAP7_PIG
Sequence: MPALRFLALLASLLATSRVGLATLADIVGGRRAQPQEFPFLASIQKQGRPFCAGALVHPRFVLTAASCFRGKNSGSASVVLGAYDLRQQEQSRQTFSIRSISQNGYDPRQNLNDVLLLQLDREARLTPSVALVPLPPQNATVEAGTNCQVAGWGTQRLRRLFSRFPRVLNVTVTSNPCLPRDMCIGVFSRRGRISQGDRGTPLVCNGLAQGVASFLRRRFRRSSGFFTRVALFRNWIDSVLNNPPA
What is the function of this protein?
This is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein.  Binds heparin.
What are the official names of this protein?
Azurocidin, Cationic antimicrobial protein CAP37, Heparin-binding protein, HBP, pHBP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Elastase subfamily.
What are the subcellular locations of this protein?
Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to azurophil granules of neutrophil granulocytes. Also called primary granules, these specialized lysosomes of the neutrophil formed early during promyelocyte development store antibacterial proteins and peptides.
Protein: BUD20_YEAST
Sequence: MGRYSVKRYKTKRRTRDLDLIYNDLSTKESVQKLLNQPLDETKPGLGQHYCIHCAKYMETAIALKTHLKGKVHKRRVKELRGVPYTQEVSDAAAGYNLNKFLNRVQEITQSVGPEKESNEALLKEHLDSTLANVKTTEPTLPWAAADAEANTAAVTEAESTASAST
What is the function of this protein?
Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome (PubMed:23045392).  Involved in positioning the proximal bud pole signal (PubMed:11452010).
What are the official names of this protein?
Bud site selection protein 20.
What is the protein family that this protein belongs to?
Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: AIR2_CAEEL
Sequence: MENKPPVINLPEKETVNTPQKGGKFTINDFEIGRPLGKGKFGSVYLARTKTGHFHVAIKVLFKSQLISGGVEHQLEREIEIQSHLNHPNIIKLYTYFWDAKKIYLVLEYAPGGEMYKQLTVSKRFSEPTAAKYMYEIADALSYCHRKNVIHRDIKPENLLIGSQGELKIGDFGWSVHAPSNKRQTMCGTMDYLPPEMVNGADHSDAVDLWAIGVLCYEFLVGKPPFEHEDQSKTYAAIKAARFTYPDSVKKGARDLIGRLLVVDPKARCTLEQVKEHYWIQGMMEAKIRAEKQQKIEKEASLRNH
What is the function of this protein?
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of chromosome segregation and cytokinesis (PubMed:12707312, PubMed:11050385, PubMed:10983970, PubMed:9852156, PubMed:10354474, PubMed:10975519, PubMed:11050384).  The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation (PubMed:12707312, PubMed:10983970).  Required for histone H3 phosphorylation during segregation of homologous chromosomes in meiosis and mitosis (PubMed:18923084).  Required for histone H3 'Ser-10' phosphorylation (PubMed:9852156, PubMed:10354474, PubMed:10975519, PubMed:11050384, PubMed:11050385, PubMed:10983970, PubMed:12015116, PubMed:11940606).  Phosphorylates tlk-1 at 'Ser-634', which enhances its activity (PubMed:15916946).  Phosphorylates zen-4 at 'Ser-680'(PubMed:15854913).  Required for the recruitment of bub-1 to the ring-shaped domain between chromosomes during meiotic anaphase I (PubMed:20729837).  Also required for the localization of the condensin I complex subunit smc-4 to mitotic chromosomes (PubMed:11914278).  Acts at the spindle midzone and the midbody to prevent cleavage furrow regression upon chromatin obstructions during cytokinesis (PubMed:12213836, PubMed:23684975).
What are the official names of this protein?
Aurora/IPL1-related protein kinase 2, Serine/threonine-protein kinase aurora-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Chromosome. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Meiotic and mitotic chromosomes (PubMed:9852156, PubMed:18923084). During each division, relocates to the midbody microtubules (PubMed:9852156, PubMed:23684975). Localizes on chromosomes during metaphase and on the central spindle during anaphase (PubMed:25475837, PubMed:23684975). Localization to homologous chromosomes during segregation is dependent on lab-1 (PubMed:18923084).
Protein: RAB7_GIBZE
Sequence: MSSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSASYKATIGADFLTREVLVDDRQVTMQLWDTAGQERFQSLGVAFYRGADCCVLVYDVNNAKSFEALDSWRDEFLIQASPRDPPNFPFVVLGNKIDVEESKRVISNKRAMTFCQSKGDIPYFETSAKEAINIDQAFEVIARNALAQEESEEFSGDFDDPINIHIENDRDGCAC
What is the function of this protein?
Ypt/Rab-type GTPases are key regulators of membrane trafficking and intracellular vesicular transport.  They act as molecular switches that convert between GTP-bound and GDP-bound states, and regulate virtually all steps of membrane traffic from the formation of the transport vesicle at the donor membrane to its fusion at the target membrane.  In the GDP-bound state, Ypt proteins are predominantly cytosolic, solubilized through the interaction with a GDP dissociation inhibitor (GDI).  In the GTP-bound state, the proteins are membrane bound and interact with specific effector proteins that select cargo, promote vesicle movement, or verify the correct site of fusion (By similarity).  RAB7 regulates the fusion of vacuoles and autophagosomes (PubMed:26177389).  Required for ATG9 trafficking (PubMed:30044782).
What are the official names of this protein?
Ypt/Rab-type GTPase Rab7.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Late endosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: MCAT_BACSU
Sequence: MFKHTKMLQHPAKPDRPDPLFAKKMQEILGGQFGEISVAMQYLFQGWNTRGNEKYKDLLMDTATEELGHVEMIATMIARLLEDAPLDQQEKAAEDPVIGSILGGMNPHHAIVSGLGAMPESSTGVPWSGGYIVASGNLLADFRANLNAESQGRLQVARLFEMTDDKGVKDMLSFLLARDTMHQNQWLAAIKELEAQEGPVVPGTFPKALEKQEFSHQLINFSEGEVSAEQNWLNEKAPDGEAFEYVKEAKTFGEKPELKPAPPFVHNTLPGRE
What is the function of this protein?
Catalyzes the decomposition of hydrogen peroxide into water and oxygen.
What are the official names of this protein?
Manganese catalase, General stress protein 80, GSP80.
What is the protein family that this protein belongs to?
Belongs to the manganese catalase family.
Protein: RECF_CORGB
Sequence: MHIRSLELRDYRSWPELKVDLEPGITVFIGRNGFGKTNIVEAIGYLAHLSSHRVSSDAPLVRAHAENARVSAVAVNQGRELAAHLLIKPHAANQASLNRTKVRTPRELLGVVKTVLFAPEDLALVKGEPAERRRYLDDIIATRQPRMAGVKADYDKVLKQRNALLKTATIALRRGYGTEEGAAALSTLDTWDGQLARLGAEVMAARFALLNELGPKIYEAYTTIAPESRPAAVNYKTTIDQGLSQFSEFDAGIIEATLLTELAAKRQREIERGSSLVGPHRDDVDLMLGDQPAKGFASHGETWSFALSLRIAEFNLLKSDDTDPILILDDVFSELDAGRRQKLVGIAQEVEQVLITAAVHDDLPENLKKVLTAQHTVTVQDTDTGRISLLDVQP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SND1_PONAB
Sequence: MASSAQSGGSSGGPAVPTVQRGIVKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRAAATQPDAKDTPDEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIAESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIRDLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTILHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWRDYVAPTANLDQKDKQFVAKVMQVLNADAIVVKLNSGDYKTIHLSSIRPPRLEGENTQDKNKKLRPLYDIPYMFEAREFLRKKLIGKKVNVTVDYIRPASPATETVPAFSERTCATVTIGGINIAEALVSKGLATVIRYRQDDDQRSSHYDELLAAEARAIKNGKGLHSKKEVPIHRVADISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGIECPRGARNLPGLVQEGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLHIDGANLSVLLVEHALSKVHFTAERSSYYKSLLSAEEAAKQKKEKVWAHYEEQPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRNDIASHPPVEGSYAPRRGEFCIAKFVDGEWYRARVEKVESPAKIHVFYIDYGNREVLPSTRLGTLPPAFSTRVLPAQATEYAFAFIQVPQDDDARTDAVDSVVRDIQNTQCLLNVEHLSAGCPHVTLQFADSKGDVGLGLVKEGLVMVEVRKEKQFQKVITEYLNAQESAKSARLNLWRYGDFRADDADEFGYSR
What is the function of this protein?
Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs (By similarity).  As part of its function in miRNA decay, regulates mRNAs involved in G1-to-S phase transition (By similarity).  Functions as a bridging factor between STAT6 and the basal transcription factor (By similarity).  Plays a role in PIM1 regulation of MYB activity (By similarity).  Functions as a transcriptional coactivator for STAT5 (By similarity).
What are the official names of this protein?
Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, p100 co-activator.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Melanosome. Note=In IL-4 stimulated cells colocalizes with STAT6 in the nucleus.
Protein: YCQ3_YEAST
Sequence: MGKEKRKKLIYRFQFNSIYFFSDKKATPGNSLPSNNSKEAPPPVETWEILSVTPYFLATVAVSPPPMMTVLPAAELLTTSSNKALVPAANFSNSKTPGGPFQTMVLAFATVAANNFLDSGPLSNPCQPAGIPSLSVTVLVLASAEKASAMMKSTGKTTSTPLALAFSINFGTISAPALSKMESPISVFSKTFLKVKAIPPPMMIESTLSNKLSIN
What are the official names of this protein?
Putative uncharacterized protein YCR013C.
Protein: RL1_NOVAD
Sequence: MAKQTKKQKALVTKLGDNQKLYAVDEAIALLKDLKSAKFDESLEVSLNLGVDPRHADQMVRGMVTLPSGTGKDVKVAVFARGDKAEAALAAGADKVGAEDLLEDMQAGNLDYGRVIATPDMMGIVGRLGKVLGPKGLMPNPKLGTVTPNVAEAVKAAKGGQIEFRVEKAGIIHGGIGKLSFSDEALRANFDAFVDAIVKAKPAGAKGKYLRKVGLSSSMGPGLKIDLAQVNGG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: AS1AA_XENLA
Sequence: MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIYVGSAESEEYDQVLDSVLVGPVPAGRHMFVFQADAPNPGLIPDADAVGVTVVLITCTYRGQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHINWEENTEKLDDSNPHMHPVLSIEARPSASKGWPMSENSLNVMLESHMDCM
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly (By similarity).  Not critical for histone deposition during nucleosome assembly (PubMed:17576589).
What are the official names of this protein?
Histone chaperone asf1a-A, Anti-silencing function protein 1 homolog, XAsf1, Anti-silencing function protein 1 homolog A-A.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSN_PHOLL
Sequence: MSALAQNETIAHQIKQQGGVEAYLHAQQEKGLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSTLQNDSKRIGTQGEKLDLALLVDGLAAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLSILLIDARKGVQEQTRRHSFISTLLGIRHLVVAVNKMDLMEYRQEVFNQIKQDYMNFAGQLPTNLDVHFVPISALDGDNIVTISRNMDWYEGPTLLDILETVDVKKEASKQLLRFPVQYVSRPDLDFRGYSGTLSSGILRKGQKVKVMPSGICSQVERIVTFDGDLDFAVPGEAITVVLKDEIDISRGDLLISADDEMMVTRHALVDVVWMSEQPLVQGQNLDIKVAGKKSRGKVENIQYQVDITHLTQRVAVDLPLNAIGSVEFSFEEPLMLDSYQQNSDTGGIILVDRLTNVTVGAGLVREIQTDVYEGPKEFSEFELELNRLIRRHFPHWGARDLLGGK
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: LOLD_XANC5
Sequence: MNEIREAAVQTPEQATAVIRAEALAKTYAEGKMRTPVFDGLDLSVATGETVAIVGASGAGKSTLLHLLGGLDIPTSGEVYVAGERMSALSDAQRGKLRNQALGFVYQFHHLLPEFTALENVMMPVLLSGKDVAVAKGQALQLLESVGLGHRVEHKPSELSGGERQRCAVARALVNKPGCVLGDEPTGNLDDKTAGTVFELMLELNRAQRTSLVLVTHDRGLARRLDRVLELNQGKLRELAPSAV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL31_PYRIL
Sequence: MSEEKKVVLTREYIINLRRAYVVSRTKRAKYAVGLVRRFIARHLKVEPKAVKIGQRLNMAIWSRSIEKPPRKVHVVVEKYSDGVVKVELKE
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: MTS3_STAAU
Sequence: MNKIKVVELFAGVGGFRLGLENTKNGIFDITWANQWEPSRKIQHAFDCYSKRFKNGIHSNKDIAQVSDEEMANTEADMIVGGFPCQDYSVARSLNGELGIQGKKGVLFWQIIRYIQNTFPKYLLLENVDRLLKSPSSQRGRDFAVMLSTLNELGYNVEWRVINAADYGNAQRRRRVFIFGYKQDLNYSKAMEESPLDKIIYHNGLFAEAFPIEDYANKNRVNRTHITHDIVDISDNFSFQFYNSGIMKNGEILTIDTIPKYEKSVTLGEIIESNVDDGFSLNQDQIDKFKYLRGPKKIKRTTKDGHEYYFSEGGMSETDSLELPARTMLTSESSINRSTHFLNVDGVYRTLTPIEAERLNGFPDNWTEGMPIKMRYFCMGNALVVPLITRIGNQIEKIDSITNDEFSQLRLF
What is the function of this protein?
A methylase that recognizes the double-stranded sequence 5'-GATC-3', methylates C-4 on both strands and protects the DNA from cleavage by the Sau3AI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.Sau3AI, M.Sau3AI, Cytosine-specific methyltransferase Sau3AI, Modification methylase Sau3AI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: Y2555_GEOKA
Sequence: MSSFDQTMQFHFSEEPAETNVREVLLTVYGALQEKGYNPINQIVGYLLSGDPAYIPRHKDARALIRKIERDELIEELVKFYLQGQRKD
What are the official names of this protein?
UPF0297 protein GK2555.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: RPOB_MORIN
Sequence: MLEGGNEEISTIPGFNQIQFEGFCRFIDQGLTEELYKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKTSRDMQEQTIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRLELEIDRKARIWARVSRKQKISILVLLSAMGLNLREILENVCYPEIFLSFLKDKEKKKIKSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNTTFLLPRDILAAADHLIGMKFGMGILDDMNHLKNKRIRSVADLLQDQFGLALVRLENMVRGTMCGAIRHKLIPTPQNLVTSTTLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKASYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGHWGSLESPFYEISERSKKVRMLYLSPSIDEYYMVAAGNSLALNRGSQEEQVVPARYRQEFLTIEWEQVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLECQVALDSGVPTIAEHQGKIIYTDTEKIILSGNRDTLSIPLVIYQRSNKNTCMHQKPQVSRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNSEDAVLINERLVYEDIYTSFHIRKYEIHTHVTSHGPERITNEIPHLEAHLLRNLDKNGIVMLGSWVETGDILVGKLTPQMAKESSYAPEDRLLRAILGIQISISKETCLKLPIGGRGRVIDVRWIQKKGGSSYNPETIRVYISQKREIKVGDKVAGRHGNKGIVSKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGGLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRCSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTMVGGPIPKPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKDV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HDA1_CAEEL
Sequence: MNSNGPLMEHGKRRVAYYYDSNIGNYYYGQGHVMKPHRIRMTHHLVLNYGLYRNLEIFRPFPASFEDMTRFHSDEYMTFLKSANPDNLKSFNKQMLKFNVGEDCPLFDGLYEFCQLSSGGSLAAATKLNKQKVDIAINWMGGLHHAKKSEASGFCYTNDIVLGILELLKYHKRVLYVDIDVHHGDGVEEAFYTTDRVMTVSFHKYGDFFPGTGDLKDIGAGKGKLYSVNVPLRDGITDVSYQSIFKPIMTKVMERFDPCAVVLQCGADSLNGDRLGPFNLTLKGHGECARFFRSYNVPLMMVGGGGYTPRNVARCWTYETSIAVDKEVPNELPYNDYFEYFGPNYRLHIESSNAANENSSDMLAKLQTDVIANLEQLTFVPSVQMRPIPEDALSALNDDSLIADQANPDKRLPPQITDGMIQDDGDFYDGEREGDDRRNESDAKRAAQFESEGGEKRQKTE
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression.  Plays an important role in transcriptional regulation, cell cycle progression and developmental events (PubMed:25446273).  Histone deacetylases act via the formation of large multiprotein complexes.  Involved in the endoderm determination possibly by repressing end-1 expression.  Also involved in vulval development, possibly by repressing lag-2 expression.  Required during mitochondrial stress for the activation of genes involved in the mitochondrial unfolded protein response (mtUPR), in concert with homeobox protein dve-1 (PubMed:32934238).  Promotes normal hermaphrodite (XX) development, in concert with zinc finger protein tra-4 and nasp-1, perhaps as components of a complex (PubMed:17011494).  Plays a role in the regulation of longevity and mtUPR-associated innate immunity (PubMed:32934238).  In association with akir-1, plays a role in regulating the transcription of antimicrobial peptide genes in response to fungal infection (PubMed:30036395).
What are the official names of this protein?
Histone deacetylase 1.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=Except in the germ line where it is also cytoplasmic.
Protein: NSRR_VIBC1
Sequence: MQLTSFTDYALRTLIYLASLPKDELTNITEVTDLFGVSRNHMVKVINRLGQLGYVHTVRGKNGGIRLMKAPQEITVGGVVRDLEPLDLVNCSVEFCHITPACRLKEKLAKAKLAFLAELDDCTIEELLSDNSELLILLARP
What is the function of this protein?
Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress.  May require iron for activity.
What are the official names of this protein?
HTH-type transcriptional repressor NsrR.
Protein: ILVC_CARHZ
Sequence: MKKVYYDQDANLELLREKKIAIIGYGSQGHAQAQNLKDSGLNVVVGLHKKSKSREKAEADGFTVMKVDEAAQWADIIQILVPDQIQGELYRDKIEEHLKPGKALMFSHGFNIHYGQIVPPPDVDVFLVAPKSPGHLVRRMYLEGKGVPGLIAVYQDATGKAKDLALAYAKGIGCTRAGVFETTFKEETETDLFGEQAVLCGGVTHLIKAGFETLVEAGYAPEMAYFECLHEMKLIVDLIYEGGFSLMRYSISDTAEYGDYMVGPRIITEETKKEMKKVLEEIQNGTFAKNWILENMAGRPVYNAIKRREQEHLIEKVGAELRQMMPWLKK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: RF1_CORA7
Sequence: MSNQVSLVDDIISEYQGIEMQMADPEVAGDQSQFRKLSKRYAELRPIVAVNEELVQARQDLADAKEMAYEDHEFQSEVDRLEPLVVQLEEQLADLLAPRDEHDSEDIIMEIKAGAGGEEAALFAGDLARMYERFADKAGFQWEVLGLNESDLGGVKDMSISFKSKTPSRDGAWSVFKFEGGVHRVQRVPVTESQGRIQTSAAGVLVYPEPEEIDSVNIDDKDIRVDVYRSSGKGGQGVNTTDSAVRITHLPTGLVVTCQKERSQIQNKARALQVLQARLDQMEREAREAEAGEQRASQVRTMDRSERIRTYNWPENRITDHRIGYKANNLDSVLDGDMQDLIEALQAQERAERLEAEG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.