PharMolix/UniProtQA huggingface dataset:
Protein: PROA_LACP3
Sequence: MDATTIDLEQMGRAAKTAAMTLGQLTTLQKNTGLLAMAAALETHADTILAANKADLAAASALPEKFVDRLALTKARIADMAAGVRQVATLDDPTAQTDRAWVNEAGLTIAQKRVPLGVVGMIYEARPNVTVDAAALTFKSGNAVILRGGKEALHSNLALATVLQDALAAKELPRDAVQLITDPSRAVATQMMHLNGYIDVLIPRGGKGLIKAVVEQATVPVIETGAGNCHIYVDAHAQLQMAVAIVVNAKVQRPSVCNAAEKLLIHADVANEQLPVIAKALQDHGVELRGDERARAIVPSMHAATAEDWDTEYNDLIMAVKVVDSEEEAIQHINAHNTKHSEAIITDNYQNSQQFLQQVDAAVVYVNASTRFTDGYEFGFGAEIGISTQKLHARGPMGLAALTTIKYQVLGNGQIRKN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_FRAT1
Sequence: MSKQEKSNVEDKSLDIETAAQVETAQESASGALEELSVEEQLERAKDTIKELEDSCDQFKDEALRAKAEMENIRKRAERDVSNARKFGIEKFSKELLPVIDSIEQALKHEVKLEEAIAMKEGIELTAKMLVDILKKNGVEELDPKGEKFDPNLHEAMAMIPNPEFEDNTIFDVFQKGYMLNGRIVRAAKVVIVKN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_THEP3
Sequence: MKRSEFYFELPEELIAQEPLEDRASSRLMILNKKTGEIEHDIFKNITKYLKPGDCLVLNNTKVIPARLIGRREDSGGKIEFVLLKRISNNEWEILVKPGRRAKIGSKFVFGNGELIAEILDTTDVGGRIVRFYYEGVFEEVLDKLGEMPVPPYIKKKLKNKDRYQTVYAKYEGSAAAPTAGLHFTEELLEKIRQMGVKTVFITLHVGLGTFRPVKEEVIENHKMHEEFYIVTKEAAEEINETRKSGGRIIAVGTTSTRTLETVADEDGYIKEKSGWTDIFIYPGYKFKAIDGMITNFHLPESTLIMMVSAFAGKENIMRAYKIAVEKKYRFFSFGDAMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNPDE_HELPY
Sequence: MMQVYHLSHIDLDGYACQLVSKQFFKNIQCYNANYGREVSARIYEILNAIAQSKESEFLILVSDLNLNLNEAEYLQDKIQEHRLQNKNIQIQLLDHHISGKEVAESFHWYFLDINRCATKIVYEFLKKHYAILEPKNTTWLEPLVEMVNSVDIWDTQGYGFELGKVCMRMINQSSELNRFMFDDENRNYKLKLLEEVKNYLFLENAPVAYDNDLFKLKKIALGGDPDAETMDNISSNAQTHLLSLKKHDCSVYYQDKKGFLSYSMGGISVLANLFLTQNPDFDFYMDVNAKGNVSLRANGNCDVCELSQMCFNGGGHRNASGGKIDGFRESFNYRDIKEQIEEIFNNA
What is the function of this protein?
Hydrolyzes cAMP to 5'-AMP and cGMP to 5'-GMP.  Does not show phosphohydrolase activity toward various phosphatidylcholine and phosphorylated sugars.
What are the official names of this protein?
3',5'-cyclic-nucleotide phosphodiesterase, cAMP/cGMP phosphodiesterase.
Protein: E4PD_PSET1
Sequence: MAIKLAINGFGRIGRNIVRALYESGLSNEIKIVAINELADPEAIAHLLKYDTSHGRFFFPVKLGEDTISVAGDAIALFCEPNPAELPWKTLGVDVVLECTGVYHSREHAQLHLTAGAKKVLFSHPADNDVDATIVYGINDDELKPEHTIVSNGSCTTNCVVPVIKVLDDAFGIESGAITTIHASMNDQPVIDAYHHDLRRTRAASQSIIPVDTKLARGIDRILPKFKGRFEAIAVRVPTINVTAMDLSVTVNTDVDLNAVNNALKAQAKDRLEGILSYTAEPLVSIDFNHDPHSCIIDGTQTRVSHKRLIKLLVWCDNEWGFANRMLDTARAMVALEKITNIK
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_MOOTA
Sequence: MATPRVHVKKGDTVMVITGKDAGKKGKVLSVEPARGRVVVEGVNIVKRHTRPTQKMPQGGIIEKEAPVASSNVMLFCNKCNRPTRIGRQILADGTKTRVCKKCGEVID
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y7326_AFIC5
Sequence: MTQPIGLDGLPEKASSSGTTYLDGQLLIAMPVMQDERFARSVIYVCAHSPDGAMGIIVNRPAGSIDFPQLLRQLDIVADGVPIQLPDDGETVKILRGGPVETSRGFVLHSSDYAIEDATLPIDNGICLTATLDILKAIAQGTGPRRAVLALGYAGWAPGQLESEIQHNGWLHCPADPDIVFGRDMDDKYQRALQKIGIDLGMLSNSAGHA
What are the official names of this protein?
UPF0301 protein OCAR_7326/OCA5_c07920.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: RL5_PELPB
Sequence: MDKNKEMTPTTPSLARLETFFKEKVTPNLVERFQYKNAMLVPKLKKISINIGVGAAAAEPKLLEIALQELAQITGQKPQIRKSKKAISNFKLREGQAIGCRVTLRRKAMYEFFDRFVSLAVPRIRDFRGLSDTSFDGRGNYTVGVREQIIFPEIDIDKVPRISGMDISFVTSASTDEEAYVLLSELGMPFKKKNN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GSTUP_ARATH
Sequence: MADEVILLDFWPSMFGMRTRIALEEKNVKFDYREQDLWNKSPILLEMNPVHKKIPVLIHNGNPVCESLIQIEYIDEVWPSKTPLLPSDPYQRAQAKFWGDFIDKKVYASARLIWGAKGEEHEAGKKEFIEILKTLESELGDKTYFGGETFGYVDIALIGFYSWFEAYEKFGSFSIEAECPKLIAWGKRCVERESVAKSLPDSEKIIKFVPELRKKLGIEIE
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U25, AtGSTU25, GST class-tau member 25.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MIP_LEGPH
Sequence: MKMKLVTAAVMGLAMSTAMAATDATSLATDKDKLSYSIGADLGKNFKNQGIDVNPEAMAKGMQDAMSGAQLALTEQQMKDVLNKFQKDLMAKRTAEFNKKADENKVKGEAFLTENKNKPGVVVLPSGLQYKVINSGNGVKPGKSDTVTVEYTGRLIDGTVFDSTEKTGKPATFQVSQVIPGWTEALQLMPAGSTWEIYVPSGLAYGPRSVGGPIGPNETLIFKIHLISVKKSS
What is the function of this protein?
Essential virulence factor associated with macrophage infectivity.  Exhibits PPIase activity.
What are the official names of this protein?
Outer membrane protein MIP, Macrophage infectivity potentiator, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: Y357_RICBR
Sequence: MENNISNVRIHLHRKCDVNEQDIYGKTALHYAYTKRNIDIIKILLKCPGIKICIKDNDDYTPVDLICSTISSYIASSLENKIDEVDKLGETPHYENG
What are the official names of this protein?
Putative ankyrin repeat protein RBE_0357.
Protein: PUR9_LISMF
Sequence: MKRALISVSDKNGIVPFAEKLVELGVEIISTGGTKAAFEQAGVPVTGIEEVTEFPEMLDGRVKTLHPAIHGGLLARRDTAEHMEAIAAHDIKPIDLVVVNLYPFQETIQKSGVTLEEAIENIDIGGPSMLRSAAKNYAAVTVVVDTADYDTVLTELEEHGATTFETRQRLAAKVFRHTAAYDALIAEYLTNITGETFPEKVTLTYNRKQVLRYGENPHQDAAFYTEPGTVENSISSAKQLHGKELSYNNIRDADAALKIASEFTEPVAVAVKHMNPCGVGVGENIEEAYLKAYEADETSIFGGIVALNKEVDAKTAEHMSKIFLEIIIAPSFSEEAFAILAKKKNIRLLTVPFAGSVKGFEKTSVNGGLLIQASDSVIEDTASYEVVTEKQPTEAEMKALIAQWKIVKHVKSNAIVVGSDKQTLGIGAGQMNRIGSALIALKQAGEKAKGAVLASDAFFPMDDTVEAAAKAGITAIIQPGGSIKDKESIEMANKYGISMVLTHVRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: AZOR_MYCCT
Sequence: MSKVLVLKTTAQADEVSNSVALTNRFLEEYKKFNPDDEIIIVDLNKDEVGTSILTSETFPTFYQQEVTKKYINLLKSVDKLVIACPMYNFSTPVTLKSFIDHVSVANETFSYKYSKKGDAIGLITNLKAQILGVQGAPLGWYPWGQHTQYVEGAMRFLGIEFNKTVLLAGVKVAPLLELTPAQRVETIIDEVIQAAKTF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: RL35_THEP3
Sequence: MPKMKTHRGAAKRFKVLKSGKVKRSRAYKSHLLTHKNAKRKRRLRKATYLVGADAKNIKRLLPYS
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: API3_SOLTU
Sequence: NSSYRIISIGRGALGGDVYLGKSPNSDAPCPDGVFRYNSDVGPSGTPVRFIPLSTNIFEDQLLNIQFNIPTVKLCVSYTIWKVGNLNAYFRTMLLETGGTIGQADNSYFKIVKSSKIGYNLLSCPFTSIICLRCPEDQFCAKVGVVIQNGKRRLALVNENPLDVLFQEV
What is the function of this protein?
Inhibitor of cathepsin D (aspartic protease).  May also inhibit trypsin and chymotrypsin (serine proteases).  Protects the plant by inhibiting proteases of invading organisms.
What are the official names of this protein?
Aspartic protease inhibitor 3, API-3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RPOZ_BRUO2
Sequence: MARVTVEDCVDKVENRFELVLLAGHRARQISQGAPITVDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEAAPAQIANAAEEIAEGIAEAGEEDVVTFDRMSEEELLAGIEGLVAPEKNDGF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SLYX_SALPA
Sequence: MEARLAELESRLAFQEITIEELNLTVTAHEMEMAKLRDHLRLLTEKLKASQPSNIASQAEETPPPHY
What are the official names of this protein?
Protein SlyX.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: ATPF_DICT6
Sequence: MFSFNLLTIVSSIVNLLALAWIIKRYFLGAIIRIMNERREKIEAAMKEAEKKLQEAEDLRKQREAQLAQARDEAAKIIKEAVDTAEKMKRDITAKAEEEAEKIIVKAHEIATAERKRVLETAKKEVLAFSRLIIKEFFKRFLPVEAEELLISQFAESLDSAIANIKSDNIEEVKFISPDNVSSQLKKKIEDKLRSLLPGNWKFIFDVDPSIGLGFKLFIGEFLIDHSLDYHLSQIYETIREVENI
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: EFP_LACP7
Sequence: MISAGDFRNGLTLEIDNAVYQVIEFQHVKPGKGAAFVRTKLRDIKNGGLTERTFRPQEKYPQAHIERSDMQYLYSDGELYNFMNVETFDQIALNDEAVGDSLKFVKENDMVKMLSHQGNVFAIEPPLFVELVIVDTEPGFKGDTAQGATKPAKVETGATVYVPLFVNQGDKISIDTRTGDYMKRV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HD6_ORYSJ
Sequence: MSKARVYADVNVLRPKEYWDYEALTVQWGEQDDYEVVRKVGRGKYSEVFEGINVNNNEKCIIKILKPVKKKKIKREIKILQNLCGGPNIVKLLDIVRDQHSKTPSLIFEYVNNTDFKVLYPTLTDYDIRYYIYELLKALDYCHSQGIMHRDVKPHNVMIDHELRKLRLIDWGLAEFYHPGKEYNVRVASRYFKGPELLVDLQDYDYSLDMWSLGCMFAGMIFRKEPFFYGHDNHDQLVKIAKVLGTEALNAYLNKYHIELDPQLEALVGRHSRKPWSKFINADNQHLVSPEAVDFLDKLLRYDHQDRLTAREAMAHPYFLQVRAAENSRARPQ
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  It can phosphorylate a large number of proteins (By similarity).  Involved in photoperiod sensitivity (PS).  Increases days-to-heading under natural day (ND) and long day (LD) conditions, but not under short day (SD) conditions (By similarity).
What are the official names of this protein?
Casein kinase II subunit alpha-2, OsCKA2, Protein HEADING DATE 6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_LEPBJ
Sequence: MSAISSVFSSDKSVFIPYISLGDPDYESCISWADALIRGGAGILELGIPFSDPVADGPVIQKAFKRALAYPFSMKKILEITAEIHKLHPETPLVYLTYFNPLYSMGLEAFTESAKNSGIQGLIIPDLPFDTSEAEEFFSQLERKKIDFIHLVTPATTIDRIQSMKSFASGFIYYVTSYGVTGERRALAVGLKERIQMVRNKVGLPVCAGFGISTADQAKEISTYANGVIIGSAVQKIIEESGSNREVCISKLFTYASEIRASMK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: QUEA_HAEI8
Sequence: MRVSDFNFDLPDELIARYPKTDRVSCRLLQLNGENGEIFHRTFSDVLDLIDQGDLLIFNNTHVIPARMFGRKASGGKIEVLVERMLDEHRFLAHIRSSKSPKEGAELFLGEDKLGENNGIKAVMKARHSSLFEVELSDKSTALLDVLQTIGHMPLPPYIDRPDEEADKECYQTVYSKVPGAVAAPTAGLHFDKNLLEKLKAKGVNFEFVTLHVGAGTFQPVRVENIEDHVMHAEYVEVSQEVCNAIIATKKAGKRVIAVGTTSVRSIESAALSAEEFGNPDLIEPYFSDTSIFIYPGKKFRVVDCLITNFHLPESTLIMLVSAFAGYKNTMNAYKHAVQEKYRFFSYGDAMFINKNSNVRELE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_COPPD
Sequence: MSRIGKKPVVVPKGVTVTIDGSTVTVKGPKGTLTRTFDPRIKISLIEDQIIVERTSEEKEVRALHGTTRALIQNMVTGVSEGFSVTLKIRGVGYRAELKGKDLQMSLGFSHPVVIQSIEGIQFQVPSADTVVVSGIDKQLVTQVAANIRRYRIPDAYKGKGIWYEGEQRPLKPGKAVGKGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: PP144_ARATH
Sequence: MINLTRQRYRVSNLVTGGTSLDVILSHSPNKFTFPPLLKSCAKLGDVVQGRILHAQVVKTGFFVDVFTATALVSMYMKVKQVTDALKVLDEMPERGIASVNAAVSGLLENGFCRDAFRMFGDARVSGSGMNSVTVASVLGGCGDIEGGMQLHCLAMKSGFEMEVYVGTSLVSMYSRCGEWVLAARMFEKVPHKSVVTYNAFISGLMENGVMNLVPSVFNLMRKFSSEEPNDVTFVNAITACASLLNLQYGRQLHGLVMKKEFQFETMVGTALIDMYSKCRCWKSAYIVFTELKDTRNLISWNSVISGMMINGQHETAVELFEKLDSEGLKPDSATWNSLISGFSQLGKVIEAFKFFERMLSVVMVPSLKCLTSLLSACSDIWTLKNGKEIHGHVIKAAAERDIFVLTSLIDMYMKCGLSSWARRIFDRFEPKPKDPVFWNVMISGYGKHGECESAIEIFELLREEKVEPSLATFTAVLSACSHCGNVEKGSQIFRLMQEEYGYKPSTEHIGCMIDLLGRSGRLREAKEVIDQMSEPSSSVYSSLLGSCRQHLDPVLGEEAAMKLAELEPENPAPFVILSSIYAALERWEDVESIRQVIDQKQLVKLPGLSLSG
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g02750.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: MTNU_BACSU
Sequence: MKWTISCLQFDISYGKPSENIKKAEFFIEKESKHADVLVLPELWTTGYDLANLDELADEDGRSAQSWLKKTAKKHGVHIVAGSVAVRKNSDVYNTMYIADKEGQIIKEYRKAHLFQLMDEHLYLSAGSEDGYFELDGVKSSGLICYDIRFPEWIRKHTTKGANVLFISAEWPLPRLDHWKSLLIARAIENQCFVAACNCTGSNPDNEFAGHSLIIDPWGRVLAEGGREEGIVRAEIDLQESAEVRESIPVFDDIRKDLY
What is the function of this protein?
Involved in the methylthioribose (MTR) recycling pathway (PubMed:12022921, PubMed:24837359).  Probably catalyzes the conversion of 2-oxoglutaramate to 2-oxoglutarate (PubMed:24837359).
What are the official names of this protein?
2-oxoglutaramate amidase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: H2B6_ARATH
Sequence: MAPRAEKKPAEKKPAAEKPVEEKSKAEKAPAEKKPKAGKKLPKEAGAGGDKKKKMKKKSVETYKIYIFKVLKQVHPDIGISSKAMGIMNSFINDIFEKLASESSKLARYNKKPTITSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.6, H2BAt, HTB9.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ATA_ASPTN
Sequence: MTFSNRVSVAIIGGGIGGLSLAIGLLQNKNLDVAIYETAPKFAEIGAGVALGPNAQHALALISPAAEHAFRIHATTSLSPEFEHVWFDFRNGNAGEKDGEVLSKVENETGQQTVHRAKFLDELVKLIPREIAHFGKRLIHIQKDPVSGGAQYKLFFEDGTTASADCVIGADGIHSSVRKHLLGESHPAATPVFTGTVVYRGLIPMDVARDAIGEFADNSYMWCGDGGMVMTYPIDHGETLNVVGTRNDKGRWDGPPYTRPVDEETVRNDFMGWGEIPSKVIQPTMWAILDHYPAPYYYSGNVAIMGDAAHATTPFQGAGAGQAIEDALVLSTLFQRVTHSGLVRPALAAYNNVRLRRTQKVVATSRDALRLFCFNDRYVDGDAQRWREVWNGRMDWLWGMDLEKQNRDAVNLFADIVEKQSSARETMPKFGPVPFPVATSTV
What is the function of this protein?
6-methylsalicylic acid decarboxylase; part of the gene cluster that mediates the biosynthesis of terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase (PubMed:24534845, PubMed:25265334).  The first step of the pathway is the synthesis of 6-methylsalicylic acid (6-MSA) by the 6-methylsalicylic acid synthase atX (PubMed:9003280, PubMed:9438344, PubMed:25265334).  In the biosynthesis of 6-MSA, atX utilizes one acetyl-CoA and three malonyl-CoAs as its substrates and catalyzes a series of programmed reactions including Claisen condensation, dehydration, reduction, and cyclization to yield 6-MSA (PubMed:9003280, PubMed:9438344, PubMed:25265334).  The 6-methylsalicylic acid decarboxylase atA then catalyzes the decarboxylative hydroxylation of 6-MSA to 3-methylcatechol (PubMed:25265334).  The next step is the conversion of 3-methylcatechol to terremutin via several oxidation steps involving the cytochrome P450 monooxygenase atE and probably also the cytochrome P450 monooxygenase atG (PubMed:25265334).  Lastly, atC is required for the oxidation of terremutin to terreic acid (PubMed:25265334).  No function could be assigned to atD yet, although it is involved in the biosynthesis of terreic acid (PubMed:25265334).
What are the official names of this protein?
6-methylsalicylic acid decarboxylase atA, FAD-dependent monooxygenase atA, Terreic acid biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the paxM FAD-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y2215_THIDA
Sequence: MAGHSKWANIQHRKGRQDAKRGKIFTKLIKEITVAAKMGGGDPAMNPRLRLAIEKGKAESLPKDNIENAIKRGTGQLEGVNYEEARYEGYGIGGVAVMVDCLTDNKTRTVADVRHAFTKHGGNMGTDGCVAFQFKHVGQIVLEPGASEEAVMEAALDAGADDVIPNDDGSIEVLTSPDPKAFEAVKEALEKAGFKPAVAEITMRPEAETELAGDDAAKMQKILDALESLDDVQEVYTNAVLPD
What are the official names of this protein?
Probable transcriptional regulatory protein Tbd_2215.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYR1A_HUMAN
Sequence: MHTGGETSACKPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDRRQPNISDQQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQTFRDPATAPLRKLSVDLIKTYKHINEVYYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHILDQAPKARKFFEKLPDGTWNLKKTKDGKREYKPPGTRKLHNILGVETGGPGGRRAGESGHTVADYLKFKDLILRMLDYDPKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGGSSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGTEAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSANTGPAHYMTEGHLTMRQGADREESPMTGVCVQQSPVASS
What is the function of this protein?
Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities (PubMed:21127067, PubMed:8769099, PubMed:30773093, PubMed:20981014, PubMed:23665168).  Exhibits a substrate preference for proline at position P+1 and arginine at position P-3 (PubMed:23665168).  Plays an important role in double-strand breaks (DSBs) repair following DNA damage (PubMed:31024071).  Mechanistically, phosphorylates RNF169 and increases its ability to block accumulation of TP53BP1 at the DSB sites thereby promoting homologous recombination repair (HRR) (PubMed:30773093).  Also acts as a positive regulator of transcription by acting as a CTD kinase that mediates phosphorylation of the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II) POLR2A (PubMed:25620562, PubMed:29849146).  May play a role in a signaling pathway regulating nuclear functions of cell proliferation (PubMed:14500717).  Modulates alternative splicing by phosphorylating the splice factor SRSF6 (By similarity).  Has pro-survival function and negatively regulates the apoptotic process (By similarity).  Promotes cell survival upon genotoxic stress through phosphorylation of SIRT1 (By similarity).  This in turn inhibits p53/TP53 activity and apoptosis (By similarity).  Phosphorylates SEPTIN4, SEPTIN5 and SF3B1 at 'Thr-434' (By similarity).
What are the official names of this protein?
Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Dual specificity YAK1-related kinase, HP86, Protein kinase minibrain homolog, MNBH, hMNB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: VPC17_MYCTO
Sequence: MTTWILDKSAHVRLVAGATPPAGIDLTDLAICDIGELEWLYSARSATDYDSQQTSLRAYQILRAPSDIFDRVRHLQRDLAHHRGMWHRTPLPDLFIAETALHHRAGVLHHDRDYKRIAVVRPGFQACELSRGR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  The cognate antitoxin is VapB17 (By similarity).
What are the official names of this protein?
Ribonuclease VapC17, RNase VapC17, Toxin VapC17.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.