PharMolix/UniProtQA huggingface dataset:
Protein: AMEL_RABIT
Sequence: LPLPPHPGHPGYINFSYEVLTPLKXYQSI
What is the function of this protein?
Tooth enamel proteins are produced in ameloblasts and play a role in biomineralization.
What are the official names of this protein?
Amelogenin-like protein, Tooth enamel protein.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y1772_CERSK
Sequence: MIVTTTPNIEGYQIATYHGIVTGEAILGANVIRDLFAGITDFIGGRSGAYEKELGRARETALSEMEEAARAKGANAVVGVDLDYEVINNMLMVSASGTAVTIA
What are the official names of this protein?
UPF0145 protein RSKD131_1772.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PMAP1_SCHPO
Sequence: MMDERKLSNFQIDGEKAYTGSSQGNSYLEDRQKRQNTFTKRKAGIFKKANELALLTGSEVMVLVVSETGLVHTFSTPKLENVVKSPEGQKLITESLINATTDQNESQASQAKQSSAQLSDSESGYPLDHEEMRISEENGPSHIENLNFFSDIDNFSKTSAEEIASKLFSSVSPTHETLQFDHGLQNLEGFQANEHPEMFADHSIDFYNSNNVDIPALSMLTSQTSSSSTLNLPPEPASREVKIFPKQGKRIFSPSTGIDYETTGQHSVNSPPSTYKHRRSLNKSFATRSEPQTPRKNKIRDSLQSSPLNFPPRDRPPLIPISRIAVPSTIETEERQYRGNQKIINFYAKIFEPNSGLGTSSEGASSSFPDVDPNLAQNGVPYYSLPDIDHNQFDHLRR
What is the function of this protein?
In response to mating-pheromone signaling or nitrogen starvation, it interacts with mat1-Pc.  This activates the expression of one of two mating-type-specific genes sxa2 or map3, which leads to inactivation of the P-factor.  May also interact with mat1-Mc.
What are the official names of this protein?
Pheromone receptor transcription activator, Protein map1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK22_FAGEA
Sequence: MRKKKKSLTEVSALGQYIPMSVHKARRVIDQIRGRSYKETLMILELMPYRACYPIFKIIYSAAANAKHNKGFEKEDLLVWKAEVNKGPTRKKLKPRARGRSYLIKKPTCHISVVLKDISYYEAYETLYNREKYLPSNFRLKSSGAIWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GPDA_LATSS
Sequence: MTVNVAVLGAGSWGTILANLLVENGHHVELWGNDPEKVAEINEQHTNKHYLPEFKIDSRLHATLDLNEAFEAVDVVLFVIPTQVIRLVAEQIAPVLEAKGVKPVIVTASKGLEQGSHKRISEVLTETIPADIRNGIVVLSGPSHAEDVAMKDITTLTAASTDLVQAQWIQEIFMNDYFRLYTNTDVIGVEMGAALKNVIALGAGALHGLGYGDNTKAALMTRGLAEISRLGVAMGANPLTFIGLSGVGDLIVTGTSVHSRNWRTGNALGEGQKLDDVLENMGMVVEGVATCKAAYELAQQRSVDMPITNAIYNVLYRGCDIRTEIGNLMQRSGKPEIDFK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLB_ECODH
Sequence: MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: CH60_CYTH3
Sequence: MAKQILFDRDAREKLKKGVDALADAVKVTLGPKGRNVILDKKFGSPAITKDGVSVAKDIELKDAIENMGAQLVKEVASKTADQAGDGTTTATVLTQAIFNAGLKNVAAGANPMDLKRGIDKAVSAIIADLKVQSKKISNSNEIAQVATISANNDHEIGKMIAHAMDKVGKDGVITVEEAKGTETEVKTVEGMQFDRGYLSPYFVTNTDKMEVELDRPYILIYDKKVSSMKELLPILEQVVQSGRPLLIIAEDVDGEALATLVVNKIRGALKIAAVKAPGFGDRRKAMLEDIAILTGGTVISEESGYKLENATLEYLGTAEKINIDKDNTTVVNGSGLKDNIVARVNQIKSQMENTTSDYDREKLQERLAKLSGGVAIMYIGAATEVEMKEKKDRVDDALHATRAAVEEGIVPGGGVALIRAGAALDNVAFHNEDEKTGIQIIRTAIESPLRAIVYNAGLEGSVIVQKVKEGTGDYGYNAREDRYEAMIAAGIIDPTKVTRLALENAASVASLLLTTECVVADEPEEKSAMPPMGGGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCD_CHLTR
Sequence: MGIKEDNWIRKMAIEEGMIEPFADSQVKLHPETGEKLISYGLSSYGYDLRISREFKVFTNVYNSLVDPKCFTEDALISIVDDVCIIPPNSFALARSVEYFRIPRNVLTVCIGKSTYARCGLIVNVTPFEPEWEGYVTIEISNTTPLPAKVYANEGIAQVLFFEGDATCDVSYAERQGKYQKQQGITIPFV
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: YN92_SCHPO
Sequence: MNGIRKKPATLQLHNIKTSCFIDGSDDQSDRTRSSSGDSTSNSLKLSHHISDELINAIYKELKSPVSPWDKNISQHSPWLLEAASNSIGDSSPLLSPISPLKLRFHKYSVSKQLNSVGKQGFGLSSNHSRYASPSSPARLARGALGEELSNSQYRLECAAIQKLVAQKRANRRSSKSTLKNSANDIEFFDIEEVSSRKGLIDRTPSKRNVTSRVSDAYSRLKSAVKGESSLSFKRNRSKSKRKIQHLGLTEFNGWEHHQCDWL
What are the official names of this protein?
Uncharacterized protein C146.02.
Protein: RBL_PINLO
Sequence: MSPKTETKASVGFKAGVKDYRLTYYTPEYQTKDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEETQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDVTLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEVIREACKWSPELAAACEIWKEIKFEFDVIDRL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMF_ERWT9
Sequence: MSHTSRVFFPPAFVEQMQQLLPDADEFQRFITSSQLPLRRSLRVNTLKISVDDFLTLVEPYQWALTPIPWCQEGFWISRDDADTLPLGSTAEHLAGLFYIQEASSMLPVSALFDGGDMPQRVMDMAAAPGSKTTQIAAHMGNRGAILANEYSASRVKVLHANLSRCGVSNTAMTHFDGRVFGPALPECFDAVLLDAPCSGEGVVRKDADALRNWSQSSTEEIAATQQALINSAFHALRPGGTLVYSTCTLNTRENQQVVNGLLEQYPDAVKVEPLDTLFMGAERATTAEGYLHVFPHIFDSEGFFVARLRKVASVPPMPQPGYKVGKPPFTPLNRVQQQEVIAAAASVGLRWDTELKLWQRDKELWLFPSEIEPLLGRVRFSRIGLKLAETFPKGFRWQHHAAVALADAASANAFELNSNEAEEWYRGRDIYPERDLPASELIICYQQRPIGIAKKVGSRIKNNYPRELVRDGKLFTL
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED19_XENTR
Sequence: MEGFSGLFAASEPSSIPSAPGPPSVVPTCTGAFVSGKTQTSTPTVPGPPLPIPPPLSSSSSGEDSSRRPAAGPFYILRELPGLSDLTGSVNLILHYNLEHSFSKFCGKKMKEKLSNFLPDLPGMIDTPGAQDNSSLRSLIEKPPICGNSFTPLTGALLTGFRLHTGPLPEQCRLMHIQPPKKKNKKHKQSRTQEPAPPETPSDSDHRKKKKKQREDDPERRRKKKDKKKKKSRHSPEHPGAGSSQSGLR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y815_CLOBM
Sequence: MPRPTKFRRVEFFPENNYFVPWGKPKCEMHEVVLKVEELEAMRLKDIEELNQEQCAEKMEISRQTFQNIIDSARKKVAIALTEGKAIKISGGHYTTKLCKLKCIDCGEIYEINYEQDRHLCPNCGSEKVICNKKADFCRRWCKGQNRKEQYEESKNK
What are the official names of this protein?
UPF0251 protein CLK_0815.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: ZAPB_VIBCH
Sequence: MSFEVLEKLEAKIQTAVDTIALLQMEVEELKEEKQQLQNEAQELREAREALEQRAQQVQQEHAAWQERIRSLLGKMEDVE
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: RPOE_STRPI
Sequence: MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQNYLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDDEVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAYDAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE
What is the function of this protein?
Participates in both the initiation and recycling phases of transcription.  In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling.
What are the official names of this protein?
Probable DNA-directed RNA polymerase subunit delta, RNAP delta factor.
What is the protein family that this protein belongs to?
Belongs to the RpoE family.
Protein: NUON_CERS5
Sequence: MPSFAALLPVILLGAGAVTAMLAAPRLPGLARWIAGFALVAASVALALRLGAPDGLSVLLADDRMSRLTGLVVCLSGIGSLAFLRPDGPSKEGPALLLLATLGGVVLTGAVHAASLFLGLELITLALVALFVLPLDRPALEAGYKFLILGAAAAATLLMGLALGHAATGSLALEAFGGREALLTFAAALLLAGLAFKLALVPFHMWTPDAFTGAPGAAAAFAGAASKVAVVTALVRLDAVGLPQVWALGLGTFAGVSILLGNLAALRQDGVARMLGYSSVGHAGYIAAALATGAASAPAAALFYIVTYAPALLAALCVAALIGRATRISDLRGIVWRRPLAGAAMAAALVSLAGLPVSAGFFGKYVIFTALIEGRAWALLALAIAGSALGAYYYLRFVALIFRRAPDPADPAVRWPERTLLGAATAIILLLGIRPDLLLDQIRAALP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROC_KORCO
Sequence: MGGDIFGRELRLISFGESHGPVVGAIVEGAPAGLPLSEEDVQRILDLRRPGQSELVSQRAERDRVEILSGVFNGFTTGAPISMIVRNEDIDSSYYEEISRFPRPGHADYVARLKYSGYNDFRGGGRFSGRLTVSMCMAGAVAMKILEKLGIEVMAYSLEIGGERAEGFTLDDARNYRYMNPVRAPNEESYLRMAAAIERARREGDSLGGIVEAIALNVPPGLGEPIFDTIEGDIAKAMFSIPAVKGVEFGSGFRAARMRGSEHNDPIRVIDGKIRYKKNDHGGAIGGITTGEPIILRVAFKPTPSIAKPQETVDLELLRNVEIKVKGRHDPCVVPRAVVVVESMLAFTIADHIMRSMRGAI
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: UPP_CLOBM
Sequence: MSKVTQIAHPLILHKLALIRDKNTGSKDFRELVEEVAMLMAYEVTRDLQLKEVEIETPICKTKCKMLSGKKVAIVPILRAGLGMVGGMTSLIPAAKVGHIGLYRDEETLKPVEYFCKLPQDIGDRDVIVTDPMLATGGSAKDAITLLKQKGAKHIRLMCLVAAPEGIKEVMDEHPDVDIYVASVDEKLNEKGYVVPGLGDAGDRLYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PORTL_SHV21
Sequence: MNSGLSSAIIPVHPTKISVHLFEILQGKYAYVKGQTLHSSLRNPGVFSRQLFIHIYKTVLSSCTYDHVISDWHKYEDNIKTRWKNENFTSDSFRKSTYQSWAQTMRMTIDQLVLNNIYQIIHSKITSYERYTDWVMALGLVPVVKQLPDEKLIRQIQSQLSAASKIAAGNDRVMRTILSALEYTVTDMLETLTSIYIPDYSEVTIDYRSKDQLFVGTYKGKHIAVEVITRPVIAKNIFFDSPVQRLFQNIMSCYRTTEHAKLCQLLNTAPIKAICGASTQNVYKDILSHLEQNSQKSDPKRELLSLLVKLAENKTVSGVTDVVEEFITDVSQNIVDKNKLFGSQESTTQGLKKHVSNNVFKCLTSQINEQFDTINKLEKERELYLGKINQIETQLLHLTQDEKQSVSPDNVLVSDTFCSLQTLQSSKLSMTSSDVPKGAAVLNSFFSQYVPPFRELNKDLTLLWESEIFHTFKLTPVVDPQGQRLYVKYTQDTVTILIGPFTYSITKLHQMELINDIFVSMSFNDIASYIYSTSRLAVYIADIGNKYCPSETDGSSSSSVTGS
What is the function of this protein?
Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging.  Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid.  Binds to the molecular motor that translocates the viral DNA, termed terminase.
What are the official names of this protein?
Portal protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae portal protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ACL7B_HUMAN
Sequence: MATRNSPMPLGTAQGDPGEAGTRPGPDASLRDTGAATQLKMKPRKVHKIKAVIIDLGSQYCKCGYAGEPRPTYFISSTVGKRCPEAADAGDTRKWTLVGHELLNTEAPLKLVNPLKHGIVVDWDCVQDIWEYIFRTAMKILPEEHAVLVSDPPLSPSSNREKYAELMFETFGIPAMHVTSQSLLSIYSYGKTSGLVVESGHGVSHVVPISEGDVLPGLTSRADYAGGDLTNYLMQLLNEAGHAFTDDHLHIIEHIKKKCCYAAFLPEEELGLVPEELRVDYELPDGKLITIGQERFRCSEMLFQPSLAGSTQPGLPELTAACLGRCQDTGFKEEMAANVLLCGGCTMLDGFPERFQRELSLLCPGDSPAVAAAPERKTSVWTGGSILASLQAFQQLWVSKEEFEERGSVAIYSKC
What are the official names of this protein?
Actin-like protein 7B, Actin-like-7-beta.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: HEM1_YERPA
Sequence: MTLLALGINHKTAPVSLRERVTFSPESMDQALNSLLQQPLVQGGVVLSTCNRTELYLSVEQQENLHEQLTAWLCNYHKLSPDDVRQSLYWHHGNDAVRHLMRVASGLDSQVLGEPQILGQVKKAFAESQRGQSLSSELERLFQKSFSVAKRVRTETEIGASAVSVAFAACSLARQIFESLSELHVLLVGAGETIELVARHLREHQVKHMIIANRTRERAQSLASEVGAEVITLPEIDARLADADIIISSTASPLPIIGKGMVERALKTRRNQPMLFIDIAVPRDIEPEVGKLSNAYLYSVDDLQAIIQHNMAQRQAAAVQAESIVQQESMNFMTWLRAQGAVETIRDYRSQAEQVRSEMTAKALVAIEQGANVEQVINELAYKLTNRLIHAPTKSLQQAASDGDMERLQLLRDSLGLDQH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: TGBR3_RAT
Sequence: MAVTSHHMIPVMVVLMSACLATAGPEPSTRCELSPINASHPVQALMESFTVLSGCASRGTTGLPREVHVLNLRSTDQGPGQRQREVTLHLNPIASVHTHHKPIVFLLNSPQPLVWHLKTERLAAGVPRLFLVSEGSVVQFPSGNFSLTAETEERNFPQENEHLLRWAQKEYGAVTSFTELKIARNIYIKVGEDQVFPPTCNIGKNFLSLNYLAEYLQPKAAEGCVLPSQPHEKEVHIIELITPSSNPYSAFQVDIIVDIRPAQEDPEVVKNLVLILKCKKSVNWVIKSFDVKGNLKVIAPNSIGFGKESERSMTMTKLVRDDIPSTQENLMKWALDNGYRPVTSYTMAPVANRFHLRLENNEEMRDEEVHTIPPELRILLDPDHPPALDNPLFPGEGSPNGGLPFPFPDIPRRGWKEGEDRIPRPKQPIVPSVQLLPDHREPEEVQGGVDIALSVKCDHEKMVVAVDKDSFQTNGYSGMELTLLDPSCKAKMNGTHFVLESPLNGCGTRHRRSTPDGVVYYNSIVVQAPSPGDSSGWPDGYEDLESGDNGFPGDGDEGETAPLSRAGVVVFNCSLRQLRNPSGFQGQLDGNATFNMELYNTDLFLVPSPGVFSVAENEHVYVEVSVTKADQDLGFAIQTCFLSPYSNPDRMSDYTIIENICPKDDSVKFYSSKRVHFPIPHAEVDKKRFSFLFKSVFNTSLLFLHCELTLCSRKKGSLKLPRCVTPDDACTSLDATMIWTMMQNKKTFTKPLAVVLQVDYKENVPSTKDSSPIPPPPPQIFHGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGETARRQQVPTSPPASENSSAAHSIGSTQSTPCSSSSTA
What is the function of this protein?
Binds to TGF-beta.  Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
What are the official names of this protein?
Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted. Secreted, extracellular space, extracellular matrix. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.
Protein: NUOH2_SOLUE
Sequence: METVLNHPLFMPVLVTLVIIAAFPLVAGYIVLVERKVLADFQVRLGPMRCGPHGLLQPIADALKLLLKEDIIPTDSDKAIFWFAPCISTITGLVAFAVIPFARKIYVADVNVGLLVISATSAVGILGIILGGWSSNSHYSLLGALRSAAQLVSYEVALAFALLSGVMVAGTLSMQGIVQSQADRGVWGIFANYGFMVVPFVLYIIAATAETNRAPFDLPEAESELVAGFHTEYSGFRWALYFLAEYANIFVISSVAVTLFWGGWLRPFSSVAWLEKPLNYGVPVILFVGSGLLTFTLIRKVVDPMQQKVLLGVVVLLVLIGAIMAIPMVNDAMIGLFWFLVKVSVIIYTMIWFRGTFPRYRYDQLMNIGWKIAIPVGMASVMVNAVLGMLGKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 2, NADH dehydrogenase I subunit H 2, NDH-1 subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LAT1N_HUMAN
Sequence: MAGAGPKRRALAAPVAEEKEEAREKMLASKRADGAAPAGEGEGVTLQRNITLLNGVAIIVGAIIGSGIFVTPTGVLKEAGSPGLALVMWAACGVFSIVGALCYAELGTTISKSGGDYAYMLDVYGSLPAFLKLWIELLVIRPSSQYIVALVFATYLLKPLFPSCPVPEEAAKLMACHCVH
What are the official names of this protein?
Putative L-type amino acid transporter 1-like protein MLAS, hLAT1 3-transmembrane protein MLAS, hLAT1 3TM MLAS.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS12_UREP2
Sequence: MPTIAQLIRNKRAPKVKKTKSPALLFTYNSLHKKTTKNPSPLKSGVCTRVGTMTPKKPNSALRKYAKVRLSNGFEVLAYIPGEGHNLQEHSVVVIRGGRVKDLPGVRYHIVRGAGDASGVEKRRQQRSLYGAKRPKKEASK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SYP_PHOLL
Sequence: MRTSQYLLSTLKETPADAEVVSHKLMLRAGMIRKLASGLYNWMPTGIRVLKKVEKIVREEMNNTGAIEISMPVVQPADLWQESGRWEQYGPELLRFVDRGDRPFVLGPTHEEVITDLIRNEVSSYKQLPLTLFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHATQTSLQETYDNMYEAYSKIFTRIGLDFRAVLADTGSIGGSASHEFQVLAASGEDDIVFSTESNYAANIELAEAVAPAHDRAVPTEDMHLVDTPNAKTIAELVEQFNLPIEKTVKTLMVHAAEGTSHKLIALLVRGDHELNEIKAEKLSLVASPLTFATEEEIRSIVGAGPGSLGPVNLPIPAIIDRSVAVMSDFGAGANINDKHYFGINWERDLPVPEVADIRNVVEGDASPDGKGTLLIKRGIEVGHIFQLGTKYSDAMKATVQGEDGHNQIVTMGCYGIGVTRIVAAAIEQNHDDRGIIWPDAIAPFQVAILPMNMHKSYRVKEVAEKLYADLRASGIDVIFDDRKERPGVMFADMELIGVPHTVVIGDRNLDNGEVEYKHRRNDEKQMLKLDNVVDYLKQQLGC
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN152_HUMAN
Sequence: METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCRLLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLVFLLGIVLHNMSCISKRFTVISCG
What is the function of this protein?
E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation.  Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability (PubMed:25936802).  Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation.  Induces apoptosis when overexpressed (PubMed:21203937).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF152, RING finger protein 152, RING-type E3 ubiquitin transferase RNF152.
What is the protein family that this protein belongs to?
Belongs to the RNF152 family.
Protein: PA21_OPICY
Sequence: DFTGVKFDNTIGCGKG
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 1, PLA2, Phospholipase OcyPLA2_1.
What are the subcellular locations of this protein?
Secreted.