PharMolix/UniProtQA huggingface dataset:
Protein: G3P_SCHMA
Sequence: MSRAKVGINGFGRIGRLVLRAAFLKNTVDVVSVNDPFIDLEYMVYMIKRDSTHGTFPGEVSTENGKLKVNGKLISVHCERDPANIPWDKDGAEYVVESTGVFTTIDKAQAHIKNNRAKKVIISAPSADAPMFVVGVNENSYEKSMSVVSNASCTTNCLAPLAKVIHDKFEIVEGLMTTVHSFTATQKVVDGPSSKLWRDGRGAMQNIIPASTGAAKAVGKVIPALNGKLTGMAFRVPTPDVSVVDLTCRLGKGASYEEIKAAVKAAASGPLKGILEYTEDEVVSSDFVGSTSSSIFDAKAGISLNNNFVKLVSWYDNEFGYSCRVVDLITHMHKVDHA
What is the function of this protein?
This antigen is associated with human resistance to schistosomiasis.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, Major larval surface antigen, P-37.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
Protein: LEUC_ACTP2
Sequence: MAKTLYEKLFDAHVVYEAAGETPILYINRHLIHEVTSPQAFDGLRVAGRQVRQIGKTFGTMDHSISTQVRDVNKLEGQAKIQVLELAKNCEANGISLFDMQTKEQGIVHVMGPEQGLTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQARAKSMKVEVRGKVNPGITAKDIVLAIIGKTTMAGGTGHVVEFCGEAIRNLSMEGRMTVCNMAIEFGAKAGLVAPDETTFAYLKDRPHAPKGKDWDDAVEYWTTLKSDDDAVFDSVVVLEAKDIAPQVTWGTNPGQVIGIDQVVPNPQEMADPVTKASAEKALAYIGLDANTDMKNIPVDQVFIGSCTNSRIEDLRAAAAVMKGRKKADNVKRVLVVPGSGLVKEQAEKEGLDKIFIEAGAEWRNPGCSMCLGMNDDRLGEWERCASTSNRNFEGRQGRNGRTHLVSPAMAAAAAMFGKFVDIRHVELN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: EX7S_BACC3
Sequence: MENKLSFEEAISQLEHLVSKLEQGDVPLEEAISYFKEGMELSKLCDEKLKNVQEQMAVILGEDGELEPFTALGDEA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_PSEPH
Sequence: MARVKRGVIARKRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQKKRQFRALWIARINAGARNNGLSYSRLIAGLKKASIEIDRKVLADLAVNEKAAFAAIVEKAKATLA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RS11_COLP3
Sequence: MAKTPVRTRKRVKKQVADGMAHIHASFNNTIVTLTDRQGNALSWATAGGSGFRGSRKSTPFAAQVAADRAGAVAKEFGLKNIEVFVKGPGPGRESAIRALNAAGFKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SXY_ECOLI
Sequence: MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQNSLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
What is the function of this protein?
Induces low levels of natural DNA uptake by inducing transcription of the competence genes (the CRP-S regulon) required for DNA transformation.  Induction of the CRP-S regulon also requires Sxy-activated promoter (CRP-S), cAMP receptor protein (CRP) and cAMP (PubMed:17068078, PubMed:22532864).  Induces CRP-S site-containing genes which are involved in genome maintenance and transcription or encoding transposases and toxin-antitoxin pairs (PubMed:19502395).
What are the official names of this protein?
Protein Sxy, Competence activator Sxy.
What is the protein family that this protein belongs to?
Belongs to the TfoX family.
Protein: YNFB_SALSV
Sequence: MNNTLSKRLCLTAMLTLAAVVYTTSAFAETSKLVIESGDSAQSRQEAAMEKEQWNDTRSLRQKVNTRAEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
What are the official names of this protein?
UPF0482 protein YnfB.
What is the protein family that this protein belongs to?
Belongs to the UPF0482 family.
Protein: APT_CERS5
Sequence: MTNKSVRDYIRTIVDFPHEGILFRDVTTLFADPRGFRIAIDQLLAPYAGMRFDKVAGLEARGFILGGAVAHQLSTGFVPIRKKGKLPGRTVSVSYQLEYGEAVVKVHDDAIQAGERILLVDDLLATGGTAEAGIRLIEQLGGEVVGCAFVVDLPDLGGRKKLEAMGMEVHALCAFEGL
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_HAMD5
Sequence: MVKSKLGVLLVNLGTPDAPTVPAIKRYLKQFLSDRRVIDTPPILWWPLLRGIVLPFRSRRVAKLYQSIWMPEGSPLLVYSDRQQKALAARLPDASVELAMSYGSPSLGDAINRLITQGIIKLVILPLYPQYSATTCGSVWDAVSGILKKYRSLPSIYFIRDYAQHPSYINALKQSVARYFEKHGQPDKLLLSFHGIPQRYVRLGDDYPKRCEDTYRALSTALGLHNNKIMMTYQSRFGWEPWLTPYTDKTLKSLPAKGIKHIQVLCPGFSADCLETLEEIKEQNKEIFLKAGGKKFEYIPALNDSPEQIDLLEQLVSLG
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YO45_SCHPO
Sequence: MDEDETTYPEALRRLLIETPAAIWQLDDESAQCNNCGGPFTWFRRRHHCRWCGKLFCYNCCNSFAKLPVSSVSVDPTEDLIPQDMFIRDPDFLANDNDDDNDSQDSSWINVRVCVNCRQQLSELKELDLPYPITTCLNDDTTTRSNNQVIQSSCGNNLQRIEEPDDFVECPVCYAPLSSFKTLSERESHVANCLSNNSSSPRNMTEFLKHARRYISMQLSETSPCLGQECIICFEEFAAGDRVARIEYCLCIFHLKCYRDWLSTGAAGCPVHAATLHLS
What is the function of this protein?
Functions as an E3 ubiquitin-protein ligase.  Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase C36B7.05c, RING-type E3 ubiquitin transferase C36B7.05c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endosome membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: GSA_TOBAC
Sequence: MAAVNGVGISWPSKLTQGQRPKLVFSPSPRRCTPSSSTIKMTASVDEKKKTFTLQKSEEAFSKAKELMPGGVNSPVRAFKSVGGQPIIIDSVKGSRMRDIDGNEYIDYVGSWGPAIIGHADDEVLAALAETMKKGTSFGAPCLLENTLAEMVISAVPSIEMVRFVNSGTEACMGVLRLARAFTGRPKIIKFEGCYHGHADPFLVKAGSGVATLGLPDSPGGPKAATSDTLTAPYNDISAVESLFEEHKGEVAAIILEPVVGNAGFIQPNLDFLAAIRKITKENDALLIFDEVMTGFRLAYGGAQEYFGITPDLTTLGKIIGGGLPVGAYGGRRDIMEMVAPAGPMYQAGTLSGNPLAMTAGIHTLKRLQGPGTYEYLDKITGELTQGILDAGKKTGHAMCGGYIRGMFGFLFAEGPVNNFSDAKKSDTEKFGRFYRGMLEEGVYFAPSQFEAGFTSLAHTSEDIQKTVAAAEKVLKQI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RISB_PERMH
Sequence: MTEINGNLSAEGLNFCIVVGRFNDLITNKLLEGAIDCIVRHGGSEDNITVVRVPGSFEIPLIAKKVAKTGKYDAVICLGAVIRGSTPHFEYVAAEVTKGIALVSLETEIPVSYGILTTDTIEQAVERAGTKMGNKGFDAALSAIEMANLIKEIR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: NUOB_PECAS
Sequence: MDYTLTRIEPDGENDRYPLQRQEIVSDPLEQHVHRSVYMGKLEHALHDTVNWGRQNSLWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADFMVVAGTCFTKMAPVIQRLYEQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAYMQALLLLKESIGKERRPLSWVVGEQGVYRANMQSERERKRGERIAVTNLRSPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL22_YERPP
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALETLTYTNKKAAGLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CAD22_HUMAN
Sequence: MRPRPEGRGLRAGVALSPALLLLLLLPPPPTLLGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLDGEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHKSHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGGGSGGGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAFQTYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAALYAGHRGDDEAQAS
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.  PB-cadherins may have a role in the morphological organization of pituitary gland and brain tissues (By similarity).
What are the official names of this protein?
Cadherin-22, Pituitary and brain cadherin, PB-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PA2A1_WALAE
Sequence: AVCVSLLGASSIRPLPLHLGQFNNMIKCTIPGSTPWWDFSDYGCYCGYGGSGTPVDQLDRCCQTHDNCYTEAQKFSGCSPYTRKYSYECSEGTLTCKSDNDECAAFVCNCDRSAAICFARAPYNSNNVDIDLEAHCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that may act in the hemostasis system of the prey (By similarity).  Exhibits hydrolytic activities, and prefers the anionic micelles (dPPC with deoxycholate) (793 umol/mg/min) to the zwitterionic micelles (dPPC with Triton X-100) (591 umol/mg/min).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 PL-I, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBP2A_DANRE
Sequence: MSLKSDSETNTSVSLEEEVRTLFVSGLPVDIKPRELYLLFRPFKGYEGSLIKLTSKQPVGFVTFDSRSGAEAAKNALNGIRFDPESPQTLRLEFAKANTKMAKSKLMATPNPSNLHPALGAHFIARDPYDLTGAALIPASPEAWAPYPLYTTELTPGLPHAAFTYPAAAAAAAALHAQMRWYPSPSESSQPGWKSRQFC
What is the function of this protein?
RNA-binding protein involved in the regulation of smooth muscle cell differentiation and proliferation in the gastrointestinal system (By similarity).  RNA-binding protein localized in Balbiani body (electron-dense aggregates in the oocyte) and germ plasm during oogenesis, and may be required to maintain germ plasm mRNA translational repression (PubMed:18582455).  Translational regulator during topographic map formation in the visual system (PubMed:27974617).  Establishes oocyte polarity through interaction with Bucky ball (BUC) (Probable).
What are the official names of this protein?
RNA-binding protein, mRNA-processing factor 2a, rbpms2a, Heart and RRM expressed sequence, hermes, Protein hermes A.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the Balbiani body during oogenesis.
Protein: UTP10_SCHPO
Sequence: MASSLQKQLKNIQSNNVLKINKIRRAPSLLYDPKVAADMDLEEIYVTAVSGFHELAVHEPRLLYFEKTLLGEQSVQVDRVLLNRTENEKIDLECVQILRLLAPFFTEKNALKVLEWLIRRFSIHEYVSDEFILSFLPFHDHPFFARILGCSKPKSRPLLFLENAIKMPVTLSRADIVHALSRDKEFFAMFAQFVQNTAESHNMYPELARFWAGTMMEVLVAWHSSNEDPNVLLDRFFLRVSYAVSYVSSIDFQIAGFMLLSSIAASLPLSPSIIPPLVSAITDRLSFDNIKPALICVGHLLQFCSSFEFDHEQLEKLESFGASSLLIELSQEHRLDEFFVSYWVSLIKSRKQKDKKRLISLLDTSISQIRVTHEQAKFLLSVIPVNQDFKALQSYRRILDSVIQPERKEGKLDNLINTLQDKKKSSTFSKKDREVLLKKISEIDSQTSFEQCLAYADSAADLDSSVFISLLSKFGDKIPFLLFCIANGSERIIILSLIELRKTIEENKDVDYQIILPVVLYSLQSKDTEVRSRALNLILTFLELRNENLEFSIIYGMDDNDNKNLRWLSPVETKYYCSDLLLDRSSEIGLDGTYLFSYIPERLFTEKKPKNASKEIAVTSFLSSHAACSKLSNVRVLLLEILTRVHGKVEDAKMQILLPRLEQLSEFNSEKFKTVSKREVEALVNCFNHTSFTSLLSFLSSNIVLSQAICRRIVEIQSHLKDPQRLEFVKAVISQDEQPHYYVDVLDSIKIPDTVFKKLIGSVRLVKEKNPAIAKRKRIDSHIFDGDVQRLTRILELLETKNAASYPKLASPLFEVLNSVIALKEDIVSSNYLLQLLLGLLYEMIGASPITELSPSIRIDTLVGCIRSTNNPQIQNKALLLVSALANAAPEAVLHGVMPIFTFMGSTVLSRDDAFSIHVIEQTVKTVISALIRLGKDFDSSLLVSCFVNAFPHIPQHRRLRLYRLVLQTIGSNRFLSVVLIQFAEKMLLAKSTNVVAIHDFCLTLVQSFSVADRIGSINQCSRFCLKSLEEQSNSDSNGKAVSLIKLDELPMDVDLATLGSLRVKVLELISLVSKAKNFAFDLAKIMENSVDSFVEIQAGLFESIKLLITLSQQSSNEMELGHVYVALRSVIHLLPNELFCTVLGKLLHDERALLRRKALSIVQQRVQQGSKVSALTALIPDVTYNISNYSDEETTQLAMDCLAVMAKRFSASPELFISPIEVVSGPYGLKNSARDVQVSAIVCITVLTNTLAARILPYLADIVNYSLSILDDARKDPEGDLLELACFSMMIDFFKVLPEFSSSYVEPTIKCALASDRAFEHDAIGELLFETIANFIPTRLLMKSIFAAWPECARLGSTAALRLLELIELALQNSSRSAIGTVYKSIFKFFLDSFDSRRSLLFAEDVDNVETQAVNVFLKFVMKLSDTTFRPLFLHLHSWALEDLYETDPSGIVSRQTFFYNFLTIFLDTLKSIVTNYYAYVLDDTIELLSSKDTNSEVRHLVNSSLVSAFENDTEEFWMVPARFGKISPVLIEQIQYAPLLDDKVLVKAIVELASVASSSDNFRSMNTQLLQYLRSSNINARLLAIQIQTQLYGRLGENWISTLPQSVPFIAELMEDDDDQVETATAELVRIIDDRLGENESLQDYLT
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).  Involved in ribosome biosynthesis (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 10, U3 snoRNA-associated protein 10, U3 protein 10 required for transcription.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GLND_RUEPO
Sequence: MFDTPAVFARITEAAAEAADNAALRGAVVAILRDVQNAGRAAIAEGFAEDPFAARPLTRAYTYLTDGMVKTAMYVASEILHPLATPTQGERIAVLAVGGFGRGEMAPFSDVDLLFLTPYKITAWAESVIESMLYILWDLRLKVGHSSRTVKDCIRLGRDDFTIRTAMLEHRFLAGHAPLARSLDQRLKSELYKDTQREFIEAKLEERDARHRKQGERYMVEPNVKEGKGGLRDLQSLYWIAKYIYEVKETAELVPLGLFTPSEYRTFVQAEEFLWAVRAHLHLVTGRATEQLTFDLQVEVAARMGYQDRAGRRGVEVFMQKYFREATRVGELTRIFLTKLEAAHMKGAPLLERIFRRRRRIKQGYKVVRGRLDVVDPEAFLADKLNLLRIFEEALRTGMLIHPDAMRLVTANLDLIDDGMRNDKEARRIFLDLLLKHGNPERALRRMNELGVLSAFVPEFEPIVAMMQFNMYHSYTVDEHTIQTIVNLAQIEKGELVESLPLASSILKAGVNRKVLYVALLLHDIGKGRPEDHSILGARIARKVAPRLGLSKADCETVEWLVRYHLLMSDMAQKRDISDPRTVRDFAKAVQTTKRLDLLTVLTVCDIRGVGPNTWNNWKATLLRALHAETKRALEMGMEALNREGRGNEAKKALRTALSDWPAGEVKTEIARHYPPYWQGFNVETHVTFAEMLRQLEHSGDPGGIEIRLDPDEDRDATRACFAMADHPGIFSRMAGALALVGANVVDARSYTTKDGYVTDAFWIQDAEGHPYEAARLPRLSQMILKTLKGEVVARDALKSRDKIKKREKAFNVPTHITFDNEGSDIYTIIEVDTRDRPGLLYDLARALAAANVYIANAVIATYGEQVVDSFYVKDMFGLKYHSEAKQRTLETKLRKAITEGAERAAAS
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: Y1154_METJA
Sequence: MKVIRDSIHKDIYLDEKELEIIDSEEFQRLRNIKQTGLTYLVYPSANHTRFEHSLGTMFIASKIAEKINADVELTRVSALLHDIGHPPFSHTLEICGYSHEVFGRKKIKHMNLDNFSKSEIIKTLNRKNLEGKIISGDVDADRMDYLLRDSYHTGTAYGMIDLPRILRSITTFESFGKVKIGILKKGIQAIESLLVARHQMYSAVYMHPTVRIADTMIKRAVIKEIQEKNLDIKDLANMDDIALVSFLRISENYLMERIDRRNLYKNLITYSYFDLNPIEKWIFVNLDEKQILSLESRFYEEFGWDIFIDIYPIPKMEEHNVYIISDEGVKRLDEVSPLAQSLKPSEMRLWNISIYAPKEKIKELRENNVKDRINKILKELDVKVESKLIDILKEYGTITGKRRFLEIAKERGISPKEFYNELHKLIFCGLIKERFNRRTYVYCLNNFVKL
What are the official names of this protein?
Uncharacterized protein MJ1154.
Protein: MSA_STAAN
Sequence: MKYLILSLVANLLVFGVLSAIGLNINILAAMMIVLVIPIMISGILFFKTNIDKTYIFFNIIFIDFYYYIYNVHLMTLPKFNNYIKAEMMELEDIDVLITSKDFGFDEILFYTLYLLLILIVLYYLKKQVKHKI
What is the function of this protein?
Accessory element involved in the expression of sarA and several virulence factors.  Modulates SarA production and/or function in a strain-dependent manner.  Affects the transcription of the accessory gene regulator (agr) and genes encoding virulence factors including alpha toxin (hla) and protein A (spa) (By similarity).
What are the official names of this protein?
Protein msa, Modulator of SarA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LADD_ONCMY
Sequence: MAMLTISLLLCAAVALNGATVLELFQDFEQALHLGAKGEDERVVAAENRNQCPTGWFQFGSRCFMFVETARSWPLAERHCVSLGANLASVHSSAEYQFLQEVVASKTGGFSTPWIGGFDAVQDRLWFWSDGSEFDYQNWKKGEPNNSGGREPCIVINWRDEYRWNDINCGNSFPSGVLQKNVEIQKNEPT
What is the function of this protein?
Lectin that binds sepharose in a calcium-dependent manner.
What are the official names of this protein?
Ladderlectin.
Protein: Y1509_MYCTO
Sequence: MFALSNNLNRVNACMDGFLARIRSHVDAHAPELRSLFDTMAAEARFARDWLSEDLARLPVGAALLEVGGGVLLLSCQLAAEGFDITAIEPTGEGFGKFRQLGDIVLELAAARPTIAPCKAEDFISEKRFDFAFSLNVMEHIDLPDEAVRRVSEVLKPGASYHFLCPNYVFPYEPHFNIPTFFTKELTCRVMRHRIEGNTGMDDPKGVWRSLNWITVPKVKRFAAKDATLTLRFHRAMLVWMLERALTDKEFAGRRAQWMVAAIRSAVKLRVHHLAGYVPATLQPIMDVRLTKR
What are the official names of this protein?
Uncharacterized protein MT1557.
Protein: FKB15_HUMAN
Sequence: MFGAGDEDDTDFLSPSGGARLASLFGLDQAAAGHGNEFFQYTAPKQPKKGQGTAATGNQATPKTAPATMSTPTILVATAVHAYRYTNGQYVKQGKFGAAVLGNHTAREYRILLYISQQQPVTVARIHVNFELMVRPNNYSTFYDDQRQNWSIMFESEKAAVEFNKQVCIAKCNSTSSLDAVLSQDLIVADGPAVEVGDSLEVAYTGWLFQNHVLGQVFDSTANKDKLLRLKLGSGKVIKGWEDGMLGMKKGGKRLLIVPPACAVGSEGVIGWTQATDSILVFEVEVRRVKFARDSGSDGHSVSSRDSAAPSPIPGADNLSADPVVSPPTSIPFKSGEPALRTKSNSLSEQLAINTSPDAVKAKLISRMAKMGQPMLPILPPQLDSNDSEIEDVNTLQGGGQPVVTPSVQPSLHPAHPALPQMTSQAPQPSVTGLQAPSAALMQVSSLDSHSAVSGNAQSFQPYAGMQAYAYPQASAVTSQLQPVRPLYPAPLSQPPHFQGSGDMASFLMTEARQHNTEIRMAVSKVADKMDHLMTKVEELQKHSAGNSMLIPSMSVTMETSMIMSNIQRIIQENERLKQEILEKSNRIEEQNDKISELIERNQRYVEQSNLMMEKRNNSLQTATENTQARVLHAEQEKAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCLALQAQITALTKQNEQHIKELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSLRREFELEESYNGRTILGTIMNTIKMVTLQLLNQQEQEKEESSSEEEEEKAEERPRRPSQEQSASASSGQPQAPLNRERPESPMVPSEQVVEEAVPLPPQALTTSQDGHRRKGDSEAEALSEIKDGSLPPELSCIPSHRVLGPPTSIPPEPLGPVSMDSECEESLAASPMAAKPDNPSGKVCVREVAPDGPLQESSTRLSLTSDPEEGDPLALGPESPGEPQPPQLKKDDVTSSTGPHKELSSTEAGSTVAGAALRPSHHSQRSSLSGDEEDELFKGATLKALRPKAQPEEEDEDEVSMKGRPPPTPLFGDDDDDDDIDWLG
What is the function of this protein?
May be involved in the cytoskeletal organization of neuronal growth cones.  Seems to be inactive as a PPIase (By similarity).  Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule-based movement.
What are the official names of this protein?
FK506-binding protein 15, FKBP-15, 133 kDa FK506-binding protein, 133 kDa FKBP, FKBP-133, WASP- and FKBP-like protein, WAFL.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, axon. Early endosome. Note=Present in axons and neuronal growth cones.
Protein: PDXY_HAES1
Sequence: MKNILSIQSHVVYGYAGNKSATFPMQLLGIDVWALNTVQFSNHTQYGKWTGMVIPKEQIGEIVQGIDNIGELHQCDAVLSGYIGSAEQVEEIIKAFHKIKERNPKAIYLCDPVMGHPDKGCVVADGVKEGLIKIAMAQADIITPNLVELRELSGLAVENFEQAIEAVKVILSKGPKKVLVKHLSRVGKNAAQFEMLLANNDGIWHISRPLHNFNKEPVGVGDLTAGLFLANLLNGKSDVEAFEHTANTVNDVMETTHNAGVYELQTIAAREWIVNPKSQYKAVKIG
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: CIDA1_BACAN
Sequence: MKWWKLSGQILLLFCFAWTGEWIAKQAHLPIPGSIIGIFLLLISLKFNLVKKEWIQDGADFLLKELILFFIPSAVAVIRYKDTLSQYGIDLILIIMISTLCVTLVTGLLTELLLKRKGSVQ
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential (By similarity).
What are the official names of this protein?
Holin-like protein CidA 1.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4063_BACC4
Sequence: MTIQTFKSTDFDVFTVDGLEERMSAIKTNIHPKLEALGEQFAEYLSKQTDENFFYHVAKHARRKVNPPNDTWVAFSTNKRGYKMLPHFQIGLWGTHAFIYFGLIYECPQKVETAHAFLEHLNDLKTNIPNDFVWSIDHTKPSVKLHKTLETEDLQKMIERLATVKKAELLVGIHISPEEFSAMTNEQFLAKIESTMQSLLPLYALCNR
What are the official names of this protein?
UPF0637 protein BCB4264_A4063.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.