PharMolix/UniProtQA huggingface dataset:
Protein: DDB2_XENTR
Sequence: MPPKRATRGRRNVELSSEEEEEQEEVSPGKRKRDIEKNGEARLKKPSKKRSGQQCASDVPCSSKESDCGTNLTNKGDKQRSIVHYLYRSTLGGNVRAKYLQTPFLRSLASYILYRTNSPFDRRVTTLEWHPTHPNTVAVGSKGGDIILWDYEELNNTLIPGIGAGGCITGMKFDPFNPNQLYTSSVAGSTVLQDFSGRNIQTFTNTEDWAMWYCSLDVSAERQCVVTGDNVGNVVLLETCGKEIWKLRLHKKKVTHVEFNPRCDWLLASASVDQTVKLWDLRNIKDKSSYLYTLPHARGVNSAYFSPWDGAKLLTTDQHSEIRVYSACDWAKPQHIIPHPHRQFQHLTAIKATWHPRYDLIVVGRYPDPLFPGYMSDELRTVDVFDGQKGNIVCQLYDPYASGIVSLNKFNPMGDLLASGMGFNILIWSREILLMMKQEEMMKALREKGVSVGRKELPNSRLPHSSAPREKPGNKGSTTESSKTRTVRESSKRGKHKDPGK
What is the function of this protein?
Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively.  Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.  The UV-DDB complex preferentially binds to cyclobutane pyrimidine dimers (CPD), 6-4 photoproducts (6-4 PP), apurinic sites and short mismatches.  Also functions as the substrate recognition module for the DCX (DDB2-CUL4-X-box) E3 ubiquitin-protein ligase complex DDB2-CUL4-ROC1 (also known as CUL4-DDB-ROC1 and CUL4-DDB-RBX1).  The DDB2-CUL4-ROC1 complex may ubiquitinate histone H2A, histone H3 and histone H4 at sites of UV-induced DNA damage.  The ubiquitination of histones may facilitate their removal from the nucleosome and promote subsequent DNA repair.
What are the official names of this protein?
DNA damage-binding protein 2, Damage-specific DNA-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Accumulates at sites of DNA damage following UV irradiation.
Protein: RFT1_HUMAN
Sequence: MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLFLAREAFRRACLSGGTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYATGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGGTMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKMT
What is the function of this protein?
May be involved in N-linked oligosaccharide assembly.  May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
What are the official names of this protein?
Protein RFT1 homolog.
What is the protein family that this protein belongs to?
Belongs to the RFT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SELO_DECAR
Sequence: MNAPESLPVEFPVFDNSFAALPEAFYTRLEPHPLPEPYVVGVSTEVADLLGLPAELMNSPQFAEIFAGNRLLPGSEPLAAVYSGHQFGVWAGQLGDGRAHLLGGLRNDQGHWEIQLKGAGRTPYSRGADGRAVLRSSIREFLCSEAMAGLGVPTTRALCVIGADQPVRREEIETAALVARVAPGFVRFGSFEHWASRDRSRELQQLADYVIDTFRPACRDAENPYDALLRDISRRTGELIAHWMAVGFMHGVMNTDNMSILGLTLDYGPFGFMEAFDAGHICNHSDHQGRYTYRNQPHVAQWNLYCLADAFLPLLKHPDISRVAVDETYGDAFAQTFERLMCAKLGLRHALPDDENFIGETFGFLQQHRPDFTLFFRRLSRLSGGLDGEAMAKADAPLRDLFVDRAACDAWLANWRARLAQTPWDDGERQASMLAANPKYVLRNWLAEAAIRKAKLKDYSDVQRLLTCLRRPYDEQPEFDDLAALPPDWASGLEVSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: SHO1_PODAN
Sequence: MPNYGSLHSPSLRKMEQSRIQYGRKRLSLGNIIGDPFALATISIAFLAWIISFFGSLFAHINQPPNTPGVNNSFPLYTWWAVVFYFFLVVGVFIVVASDSVQTYHVAIVGYLGCGLVLSTSAVHGLIYSNIGSREAAAAGMILLAMVTIVWIFYFGSAPSAVPRAYIDSFALAKESSTNRQTMNTGYGIGRPETSTSVQPPQMYTAQLNGLENPSPVGGMQSSGMRNSAVPPPFQSTLGQKSNGLPGSSDGDIAPPTEYPYRAKAIYSYEANPEDANEISFQKHEILEVSDVSGRWWQARKENGDTGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF_OLIPU
Sequence: MKTLTDSFVYLGHWPSAGSFGFNTDILATNPINLSVVFGVLIFFGKGVLNDLLDNRKQRILNTIRNSEELREGAIQQLENALARLRKVETEADQFRVNGYSEIEREKLNLINSTYKTLKQLENYKNETILFEQQRTINQVRERVFQQALQGAIGTLNSCLSNELHLRTINANIGMFGTMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HVM35_MOUSE
Sequence: ESGGGLVQPGGSMKLSCVASGFTFSNYWMNWVRQSPEKGLEWVAEIRLKSGYATHYAESVKGRFTISRDDSKSSVYLQMNNLRAEDTGIYYCTRPGVPDYWGQGTTLTVSS
What are the official names of this protein?
Ig heavy chain V-III region HPC76.
Protein: PSBX_SYNP6
Sequence: MTPTLSAFIWSLVLGGVIVVIPLTVALIFISQTDKVRRS
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ZDHC2_DANRE
Sequence: MAPSGSRSFDCWRVLYWIPVLFISLIVAWSYYAYVVQLCIETIENMGEKTVYLLIYHLLFLMFVWSYWQTIYSKPMNPLKEFHLSHVDKELLEREDRRESQQEILRRIAKDLPIYTRTMSGAIRYCDRCLLLKPDRCHHCSACDMCILKMDHHCPWVNNCVGFANYKFFMLFLAYSLLYCLFVTATDMQYFIQFWTNGLPDTQAKFHIMFLFFAASTFSVSLAFLFAYHCWLVCKNRSTLEAFRAPAFQHGTDKNGFSLGAYKNFRQVFGDEKKYWLLPIFSSLGDGCSFPTCLVNPDPEQPSIPPGRNPSVKSAGESHPFPPKPLRESQSRLLNNGQTDGSEDRDKRGTSNPALTIEKET
What is the function of this protein?
Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes.  Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC2, Acyltransferase ZDHHC2, DHHC domain-containing protein 2, Zinc finger DHHC domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Postsynaptic density. Postsynaptic recycling endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Translocates to postsynaptic density when synaptic activity decreases.
Protein: BTUC_YERE8
Sequence: MQTSHLFTALQQRQQQRDNRYLKGLVVILLLSLLISLCAGDIWLWPTQWFSETGRLFVWQLRLPRALAVLMVGASLAVSGAVMQALFENPLAEPGLLGVANGAGVALVMAVLLGHGLLPIWFLSACAIAGALLMTMLLLGFARRRLLTNARLLLVGVALGIVCSAIMTWAVYFSTSLDLRQLMYWMMGGFSGIDWRHQGLVLALLPIVLWLCCQGHVLNFMSLGEQQAQQLGVSLHLWRNLLVLAIGLLVGVSVALAGVISFIGLVIPHILRLTGLTDQRRLLAGCALAGGGILLLADIVARIALFSAELPIGVVTATLGAPLFIWLLTRVKSVK
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DF247_ARATH
Sequence: MKFAAIFLVTCVFFSLFSSNLSQGEKLSMDPTRRPWCPSKKQMFGGNCGNDGDSLCLMLLAASWDESLRHSSISCNCTTYPNYKILCSCPNMICP
What are the official names of this protein?
Defensin-like protein 247, S locus cysteine-rich-like protein 6, Protein SCRL6, SCR-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: CEFD1_ACRCH
Sequence: MAPGGLLTLAGAAAASTAAAAYLDAKLHLTKDLNQLARAERGAQNFARAVEQRKASGFFLFEAAAARLGDAPCIWSRGHPEYSWTQTYQRACQYGHYFRDLGVVAGQHVGVYLYNSPELMFIWMGLLSIGAAPALINYNLGSDALVHCVRLSRSRFLIYDDASDCSSRIHEVGERLRDINVEAIMLSGSGTTGLPKAAPITVARNYPSASLLPKTFGQKPGPNGDRTYYCIPLYHGTGGIAAMNDLMSGISIALAPKFSLSRFWDDCIESGSTIFVYVGELIRYLLSAPASPKDRQHRVRLVWGNGLSPELWTKFQDRFGVSDIGEFYASTEGVLTLLKHYRGGGFGLGAVGHHGWLLRRKFHNDYVPVRIDPETGDIWRSPKTGFAERLPYERGGEILARLPSRSAWAGYWHAEEATQKKLVENVFEKGDLYFRTGDALRRDADGHWYFLDRLGDTYRWKGENVSTTEVGQVLGSHADIAEANVYGVQVPNHDGRAGCAAIALKNAATPDTLDWSRLTSLLRSELPSYAVPVFIRVRETVGGMSTDNHKHNKVPLRDEGVDPRSMGSKVPGSEKDRFFWLPAGASKYVPFTERDWDLLSGQSAARPRL
What is the function of this protein?
Together with cefD2, catalyzes the reversible isomerization between isopenicillin N and penicillin N.  This two-component IPN epimerase system may function by two sequential steps, an activation of isopenicillin N by the acyl-CoA synthase component cefD1, followed by epimerization by the acyl-CoA racemase component cefD2.
What are the official names of this protein?
Isopenicillin N epimerase component 1, IPN epimerase component 1, Isopenicillin N epimerase acyl-CoA synthase component.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HEM2_SELMA
Sequence: MAALLVPGGGAAPGLVWRRRRAAVQCAAASPSSPDPSWRTNVVSDRVSVEPSPRTIHECEADVVSGNPPAAPAAPAKAKAPPGTPVVKPLRLTSRPRRNRKSAALRDAFQETTLTPANFILPLFIHEGEEDSPIGAMPGCSRLGWRHGLIDEVYKARDVGVNSVVLFPKIPDALKSSTGDEAYNPDGLVPRAIRTLKDKFPDLVIYTDVALDPYSSDGHDGIVREDGVIMNDETVHQLCKQAVAQAEAGADVVSPSDMMDGRVGAIRTALDEAGYYHVSIMAYTAKYASAFYEPFREELDSNPRFGDKKTYQMNPENYREALLEVHADESEGADILMVKPAMPYLHVIRLLRDTSALPISAYQVSGEYSMIKAAASQGMLDEKKAILESLLCIKRAGADVILTYAALQAARWLCGEK
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, chloroplastic, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DAPB_CAMJD
Sequence: MIKIGIYGAKGRMGKQIEECLKSETQAEISILYNKGGNLEELFEKSDVIIDFSSPSGTHELLNYARTMPKPLTIGTTGLDEKILHLMQSASKVMPIFYATNMSLGVAVLNYLASKASQMLRNFDIEILEMHHRHKKDAPSGTAMTLAQSVAKARNLELEKVRVSGRDGIIGERSKDEIAVMSLRGGDIVGRHTVGFYEDGEFLELNHTATSRATFAKGAIKIAIWLSKQEAKMYSINDFFRNLKCVQL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCRB_COREF
Sequence: MSNKLATVGNNLDSRYTMAGGIRRQINKVFPTHWSFLLGEIALYSFIILILTGVYLTLFFDPSITKVIYDGAYLPLNGVEMSRAYMTALDISFEVRGGLFVRQMHHWAALMFVVSMMVHMMRIFFTGAFRRPREANWVIGVVLLILGIAEGFMGYSLPDDLLSGVGLRIMSAIIVGLPIIGTWMHWMIFGGDFPSDIMLDRFYIAHVLIIPGIILGLIAAHLALVWYQKHTQFPGAGRTENNVIGIRIMPVFAVKSVAFGAITLGFLSLLAGVTTINAIWNLGPYNPSQVSAGSQPDIYMLWTDGAARVMPAWELYFGNYTVPAVFWVAIMLGILVVLLIAYPWIEKKLTGDDAHHNLLQRPRDVPVRTSLGVMALIFYILLTISGGNDIWAYQFDVSLNAMTWIGRIGLIVFPAIGYFVTYRLCIGLQRSDREVLEHGIETGVIKQMPNGAFIEVHQPLGPVDEHGHPIPLPYSGAKVPKQLNELGFAEVESRGGFFGPDPESVATKANEIAHANHLEEVATLAAIQEENRKRDQAEGRI
What is the function of this protein?
Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
What are the official names of this protein?
Cytochrome bc1 complex cytochrome b subunit, Cytochrome bc1 reductase complex subunit QcrB, Menaquinol--cytochrome c reductase cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MEND_STAAT
Sequence: MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLIVLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETIDAIYYQMQIASQYLYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGLIIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVDFVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLMEDTTVNRVSWLEKWQCLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMPIRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLMSKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFKRFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RLMM_HAES1
Sequence: MNKLALYCRSGFEKELAAEITEKATALGVFGFARVVENSGYVIFECYQIGEADLLARKITFSQLIFARQLIVVSDLISNLSVQDRISPIIEYYRQQEKILNLKQSSDIWVETADTNEAKTLAAFCRKFTVPLRQALRKQGWLQAKNKKSGITLHIFFTQSNSCYIGYSYNNNHAEHIMGIPRLKFPAEAPSRSTLKLEEAILYFIPPNQEATRFNENKYAVDLGACPGGWTYQLVRRGVFVYAVDHGKMATSLHETGRIEHCAEDGFKFRPPKHCKIDWLVCDMVEQPRRIADLISQWLVKGWCKETIFNLKLPMKKRYFEVQQCLRQIEDKLNKQNISFQLQAKHLYHDREEITVYIRLM
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_NANDO
Sequence: MNVLPCSINTLKGLYEISGVEVGQHFYWQIGGFQVHAQVLITSWVVMAILLGSATIVVRNPQTIPTDGQNFFEYVLEFIRDLSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALPTSVAYFYAGLTKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPSVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RNFA_ACTP2
Sequence: MVDYILLIISTALINNFVLVKFLGLCPFMGVSKKVETAIGMGMATTFVLTVASLSAYLVETYVLIPLEAQFLRTLVFILVIAVIVQLTEMIVHKTSPTLYRLLGIYLPLITTNCAVLGVALLNVNLSNNLVESVLYGFGAALGFSLVLVLFAALRERLAAADVPRPFQGASIALITAGLMSLAFMGFTGLVKI
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAJ_BURO0
Sequence: MAKRDYYEVLGVAKNASDDEIKKAYRKLAMKYHPDRNPDSKDAEEHFKEAKEAYEMLSDGQKRAAYDQYGHAGVDPNMGGAGAQGFGGFADAFGDIFGDIFGQAAGGAARGGRGGPQVYRGADLRYSMEITLEQAAHGYDTQIRVPSWVSCEVCHGSGAKPGTKPETCPTCHGQGTVRMSQGFFSIQQTCPKCHGTGTYIPEPCAHCHGSGKVKETKTLEVKIPAGIDDGMRIRSAGNGEPGINGGPPGDLYVEIHIKPHSVFERDGDDLHCQMPIPFTTAALGGEIEVPTLAGRASFPVPEGTQSGKTFRLRGKGIKGLRSSIAGDLYVHVQVETPVKLTDQQRDLLKQFEKSLAEGGARHSPQSKSWFDRVKSFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
Protein: MT2_COLGL
Sequence: MAPCSCKSCGTSCAGSCTSCSCGSCSH
What are the official names of this protein?
Metallothionein-like protein CAP5.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 8 family.
Protein: NUOH_BACAA
Sequence: MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPIGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWAFFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALANIFLTALIKELFF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y353_METJA
Sequence: MMRYSSNKIYFIVYLGGKPVSFGVAKDVDEFERRRENIECLSDKIRVVKVGKKLFKRLRRQILEGEKKDFGMLKVNRRDLNVQV
What are the official names of this protein?
Uncharacterized protein MJ0353.
Protein: TTC30_AEDAE
Sequence: MFSQNMLIRDGEYTKSIYTMIKEERFQEAINVLNGIPEVSTTRAGLSLLGHCYYQTQDFIEASNCYEYLVNLVPDVPEYKLYYAQSLFQAGLFEEAHKISTTLDAPQLKDKVLQLQSAIAYGNEDYSTAQSLLLQRQDTSQEATVKNDEGCLLFQANMFEDALQRYVSALQAGGFNPHIAYNAALCHYRKKENSQALNYIAEIVERGIRNHPELGVGAQAETEGGARSVGNPPALAASGLAQAFNLKAAIEYQEGNVEGSREALTDLPPRLEPELDPVTLHNMALTDPVGGGAGLRRLAFLLELGPPTCPPETFANLLLLCCKHEMYDTAADILAEHTHLTYKYLSPYMYDLLDALITAQSTPEEAEQKLGVLANNIGGRLRSLAAKVQECRSAPDQNALRVALREYEFALESYLPVAMARAWIPWRADDFQGAEREFRASAEFCSETPTWRLHAAHVLFMRGDRYKEAAAFYEPIVRQNYDDILAVSASVLANLCVAYIMTSQNEEAEELMRKVERAEERKGNANGQCLHLCIVNLVIGTLYCAKGNYEFGLSRIAHALDGGSGARLCADTWLHVKRCVLGLLTGLSKQTIVLPSIAIQETLSFLRTCEAYGLTIPSVLTGPLEETGEQPPTIGLEARKLRALLLRLMEYNNFVSNTW
What is the function of this protein?
Required for polyglutamylation of axonemal tubulin in sensory cilia.  Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
What are the official names of this protein?
Tetratricopeptide repeat protein 30 homolog, TPR repeat protein 30 homolog.
What is the protein family that this protein belongs to?
Belongs to the TTC30/dfy-1/fleer family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: UREE_YERPY
Sequence: MILIEHILGNVKKDPVWREKLKDATFDLLILDQREAQKSRCRKSSTQGLDLGISLDRNVVLADGDVLAWDEETNVAVVVQINLRDVMVIDLSELKSRSPDELIKTCFELGHALGNQHWKAVTKHNEVYVPLTVATTMMDSVMRTHGFQHLPFRFVKGAEILPLLTNSEARLLFGGAEDTDTHVHVASPLDEPHGSGLHIHGIHSHGEGHSHGDHDHDHSHSHGDHDHDHKH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCF2L_RAT
Sequence: MSNCWCFIFCKERVRSNSSSPQHDGTSREEADHQVDVSDGIRLVPDKAEATMATASDEIMHQDIVPLCAADIQEQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRQDKWTSVKASVLRIAASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDEFKMKVPVMMLSSVPELHGYIDKSQLTEDLGGTLDYCHSRWLCHRTAIESFALMVKQTAQMLQAFGTELAETELPNDVQSTSLVLSAHTEKKAKVKEDLQLALTEGNSILESLREPLAESIVHSVNQDQLDNQATVKRLLTQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKTALDSMSQKIAAFTDVGNSLAHVQHLLKDLTTFEEKSSVAVDKARALSLEGQQLIENRHYAVDSIHPKCEELQHLCDHFASEVTRRRDLLSKSLELHSLLETSMKWSDEGIFLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNKIYKEYECILNQDLLEHVQKVFQKQESTEEMFHRRQASLKKLAAKQTRPVQPVAPRPEALTKSPSPSPGSWRSSENSSSEGNALRRGPYRRAKSEMSEPRQGRTSSTGEEEESLAILRRHVMNELLDTERAYVEELLCVLEGYAAEMDNPLMAHLISTGLQNKKNILFGNMEEIYHFHNRIFLRELESCIDCPELVGRCFLERMEEFQIYEKYCQNKPRSESLWRQCSDCPFFQECQKKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSKHCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKKGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMTAVGITENVKGDTKKFEIWYNAREEVYIIQAPTPEIKAAWVNEIRKVLTSQLQACREASQHRALEQSHSLPLPTPASTSPTKGSTRNVKKLEDRKTDPLCLEGCVSSSLPKPPEKGKGWSKTSHSLEAPEEDGGWSSAEELINSSDAEEDGGVGPRKLVPGKYTVLMDGEKGGSDTLAMRSGDMVEVVEEGTEGLWYVRDLTSSKEGWVPASSLATLLGKSSSAQCLSSSGKTHCARQLCPEPAKILSPEPV
What is the function of this protein?
Guanine nucleotide exchange factor that catalyzes guanine nucleotide exchange on RHOA and CDC42, and thereby contributes to the regulation of RHOA and CDC42 signaling pathways.  Seems to lack activity with RAC1.  Becomes activated and highly tumorigenic by truncation of the N-terminus.
What are the official names of this protein?
Guanine nucleotide exchange factor DBS, DBL's big sister, MCF2-transforming sequence-like protein, OST oncogene.
What is the protein family that this protein belongs to?
Belongs to the MCF2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.