PharMolix/UniProtQA huggingface dataset:
Protein: RRF_FRAT1
Sequence: MINDILKDAENRMKKSLEVLADDLAKIRTGRAQPDLLAHVTIDYYGVETPITQAANITVLDARTLGITPWEKGLSSKIEKAILTSDLGLNPTNLGDSLRVPMPALNEERRKELVKLVKSETEAGRVSIRNIRRDANGDIKELLKEKEITEDQAKKAEDDIQKITDKMIAQADALAAKKEQDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSA_SALTI
Sequence: MELYLDTANVAEVERLARIFPIAGVTTNPSIVAASKESIWDVLPRLQNAIGEEGTLFAQTMSRDAKGMVEEAKRLNNAIPGIVVKIPVTAEGLAAIKLLKKEGIVTLGTAVYSASQGLLAALAGAKYVAPYVNRVDAQGGDGIRMVLELQTLLEHHAPDSMVLAASFKTPRQALDCLLAGCQAITLPLDVAQQMLNTPAVESAIEKFEQDWKNAFGNLNL
What is the function of this protein?
Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction.
What are the official names of this protein?
Fructose-6-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECA_SPAPA
Sequence: AEETSFVFSKFKPLEPNLILQGDALVTVAGVLQLTNVDKNGVPEPSSLGRATYSAPINIWDSATGLVASFATSFRFTIYAPNIATIADGLAFFLAPVASAPDSGGGFLGLFDSAVSGSTYQTVAVEFDTYENTVFTDPPYTHIGFDVNSISSIKTVKWSLANGEAAKVLITYNSAVKLLVASLVYPSSKTSFILADIVDLSSVLPEWVRVGFSAATGASGGKIETHDVFSWSFASKLAGXXTKDSSFLDGG
What is the function of this protein?
Galactose-binding lectin (PubMed:21889532, PubMed:23652482).  Exhibits hemagglutination activity in a calcium- and magnesium-dependent manner (PubMed:23652482).  Also binds to several carbohydrates including lactose, D-galactose and GalNAc in a calcium- and magnesium-dependent manner (PubMed:23652482).  Likely to have antifungal activity as it is able to inhibit the activity of the A. flavus alpha-amylase (PubMed:24460654).
What are the official names of this protein?
Seed lectin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: TX33B_TRILK
Sequence: MKLFMVLVASFAFAVALPSKKREETAENELTGDLQEAAQPMIYAVAFPEIRASCVIGWKQQGAKCERDCECCGVAATCITRSTNSLPGFCGYRQTPNVLGQGLLYTADTISNGLSAIFCAA
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Toxin ICK-23.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1419_MYCTU
Sequence: MGELRLVGGVLRVLVVVGAVFDVAVLNAGAASADGPVQLKSRLGDVCLDAPSGSWFSPLVINPCNGTDFQRWNLTDDRQVESVAFPGECVNIGNALWARLQPCVNWISQHWTVQPDGLVKSDLDACLTVLGGPDPGTWVSTRWCDPNAPDQQWDSVP
What are the official names of this protein?
Uncharacterized protein Rv1419.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MTM1_MYCPN
Sequence: MHYFNRAKKAKNNEFYTLFEDIAAEVACYPNAFKGKVVLCNCNDGYQSNFWQFFQSQFHALGLKKLVAIAFNPLGNSYQLNFDGKEIKELPLAGNGSFDSAEAIVLLKQSDIVVTNPPFSLFQDFVCLLAEHGKQFLVLGHNGAVGYNQIFKLFKEEQLWYGHTVNSSMLFQVQSNFKLYDPKSVNFVKKDGQLFQKVPGISWFTNLKKNQQPAWLKTKSRYQGNEHKYPKFDWYDAIFVSKVKEIPLDWFGYMGVPLTFLNCFNPKQFELIDCLANPYATLDTLKTNAYVRSHHGDVRNVKGKRRYVRVVIKQRQNVI
What is the function of this protein?
A methylase that recognizes the double-stranded sequence 5'-CTAT-3' and methylates A-3 on one strand; probably responsible for all of the methylation on this site in the genome.
What are the official names of this protein?
Type II methyltransferase M.MpnI, M.MpnI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: HUTI_VIBCH
Sequence: MNCVLTEARLVTMQPGVQGYQITEPQTLIIEQGRIQHIGQHIDLPSDAHPISCAGKLVTPGLIDCHTHLVYAGSRANEFELRLQGVPYQTIAAQGGGILSTVNATRKASEEALIELALPRLDGLLRSGVTSVEVKSGYGLTLKDELKMLRAAKALEQHRRVKITTTLLAAHALPPEFQGRSDDYIAHICQEIIPRVAEEQLATSVDVFCESIGFSVAQTERVFHAAQAHGLQIKGHTEQLSNLGGSALTARMGGLSVDHIEYLDEAGVKALAQSSTVATLLPGAFYFLRETQKPPIEWLRQYRVPMAISTDLNPGTSPFADLSLMMNMGCTLFDLTPEETLRAVTCHAAQALGYPANRGQIAEGYDADLAIWNIEHPAELSYQVGVSRLHARIVNGELSYES
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_STRPI
Sequence: MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISKTVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIIYTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRRDLAVSPFAPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTLLKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLLLITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGVIPVGHFADISATVADNFGVETAMIGESFLDKLV
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2616_MYCBO
Sequence: MAPRRRRHTRIAGLRVVGTATLVAATTLTACSGSAAAQIDYVVDGALVTYNTNTVIGAASAGAQAFARTLTGFGYHGPDGQVVADRDFGTVSVVEGSPLILDYQISDDAVYSDGRPVTCDDLVLAWAAQSGRFPGFDAATQAGYVDIANIECTAGQKKARVSFIPDRSVVDHSQLFTATSLMPSHVIADQLHIDVTAALLSNNVSAVEQIARLWNSTWDLKPGRSHDEVRSRFPSSGPYKIESVLDDGAVVLVANDRWWGTKAITKRITVWPQGADIQDRVNNRSVDVVDVAAGSSGSLVTPDSYQRTDYPSAGIEQLIFAPQGSLAQSRTRRALALCVPRDAIARDAGVPIANSRLSPATDDALTDADGAAEARQFGRVDPAAARDALGGTPLTVRIGYGRPNARLAATIGTIADACAPAGITVSDVTVDTPGPQALRDGKIDVLLASTGGATGSGSSGSSAMDAYDLHSGNGNNLSGYANAQIDGIISALAVSADPAERARLLAEAAPVLWDEMPTLPLYRQQRTLLMSTKMYAVSRNPTRWGAGWNMDRWALAR
What are the official names of this protein?
Uncharacterized lipoprotein Mb2616c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv2585c and M.leprae ML0489.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: URE1_COREF
Sequence: MFSMSRKQHASMYGPTTGDRLRLADTGLFAEIEEDLTIAGEEAVFGGGKVVRVGMGQNGHRTREEDPDIPDTVITNVIVLDWSGIYKADIGIRDGIITGIGHAGNPDTMDGGTIPIGVSTDIIAGEGKVLTAGGIDTHIHFISPEQIEAALVSGITTMIGGGTGPSESTKATTITPGPWHIHQMLRSLDGFPMNIGLLGKGHATASAPLIDQIRAGAIGLKVHEDWGATPATIDLSLSVADEFDIQVAVHTDTLNEAGFVESTREAIGGRVIHTFHTEGAGGGHAPDIIALAGEPNVLPASTNPTLPYTVNTVEEHLDMLMVCHHLNPDVPEDVAFADSRIRTETIAAEDVLHDMGIFSITSSDSQAMGRVGEVIIRTWQVADSMKRQRGPLEGDTADSDNNRIKRYVAKYTINPALAQGISHVVGSVETGKFADLVLWEPKFFGVKPFMILKGGQVVNSIMGDAGASIPTPQPELYRPMFGSYGSATSSNSITFLPRVAIAAGIPEQLGLNRRIEECHGIRTLTKQSLKLNGETPSIHVDPETYEVRIDGALITCEPAEKLPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_MARPO
Sequence: MDIINIAWAALMVIFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL21_RICAH
Sequence: MFAVIKAGGKQYKVDRNSIIKVEKIDGELGSKIQFDQILMIGEYSKPSFIGTPIVKGAVVTAEITNQLKDNKIIVFKKKRRKNYRRKAGHRQELTELKILDITKQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RNAS4_PIG
Sequence: MALQRTHVLLLLLLLTLLGLGLVQPSYGQDRMYQRFLRQHVDPDATGGNDAYCNLMMQRRKMTSHYCKRFNTFIHEDIWNIRSICSTSNIQCKNGQMNCHEGVVKVTDCRETGSSRAPNCRYRAMASTRRVVIACEGNPEVPVHFDK
What is the function of this protein?
This RNase has marked specificity towards the 3' side of uridine nucleotides.
What are the official names of this protein?
Ribonuclease 4, RNase 4, Ribonuclease PL3.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTH_FRATM
Sequence: MPKIKMIVGLGNIGKEYQDTRHNVGEWFIAKIAQDNNQSFSSNPKLNCNLAKVSIDYNNVVLVFPTTYMNNSGLAVSKVANFYKIAPAEILVVHDELDIDSGEIRLKKGGGHGGHNGLRSINQHLGTNDYLRLRIGIGHPGHKSKVANYVLSNPSIAQKKDIDSAIDNGICFLDDIINYKLEPVMQKLHTK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSJ_SALPA
Sequence: MTTPAPLTGLLPLNPEQLARLQAATTDLTPEQLAWVSGYFWGVLNPRSGAVAVTPAPEGKMPGVTLISASQTGNARRVAEALRDDLLAANLNVTLVNAGDYKFKQIASEKLLVIVTSTQGEGEPPEEAVALHKFLFSKKALKLENTAFAVFSLGDTSYEFFCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDVLKSRAPVAAPSQSVATGAVNDIHTSPYTKDAPLTATLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVDGKTLPLAEALEWHFELTVNTANIVENYATLTRSESLLPLVGDKAQLQHYAATTPIVDMVRFSPAQLDAQALIGLLRPLTPRLYSIASAQAEVESEVHITVGVVRYDIEGRARAGGASSFLAGRVEEEGEVRVFIEHNDNFRLPANPQTPVIMIGPGTGIAPFRAFMQQRAADGAEGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLNRIDLAWSRDQKEKIYVQDKLREQGAELWRWINDGAHIYVCGDARCMAVDVEKALLEVIAEFGAMDIESADEYLSELRVERRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: Y2252_BREBN
Sequence: MTEIKVPDLEQKALALLQADADKIYKLIDVQMENLTMPQCPLYEEVLDTQMFGLSREVEYAVRLGLISDDIGREIMGSLERKLAHLHELFNQR
What are the official names of this protein?
UPF0358 protein BBR47_22520.
What is the protein family that this protein belongs to?
Belongs to the UPF0358 family.
Protein: HIS1_BRUSI
Sequence: MSVTLALPSKGRLKEKTLAVLEKAGYKVVLPDDDRNYRARVEGEDDLDILFLSASEIARELGYGSVDLGVTGEDLVRETLAHADERVAIEAQLGFGHADVVVAVPEVWRDVTTMADLDDVAADFRQRHGRRLRIATKYWRLTQQFFSQKHGIQVYRIVESLGATEGAPAAGSADMIVDITSTGSTLRANRLKVLEDGIILRSQACLVSARRSHTSRRVEEIAARIRAGLEI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_YERPE
Sequence: MTPNILPIESYDHQLAEKSARLKAMMLPFQAPEPEIFRSPADHYRMRAEFRVWHDEDDLYHIMFDQQTKQRIRVEQFPVASRLINRLMDALMTAIRAEPLLRRKLFQIDYLSTLSGKLIASLLYHRQLDEEWQQKALELRDQLRAQGFDLQLIGRAAKTKIMLDHDYIDEVLPVAGREMIYRQVENSFTQPNAAVNIHMLEWALDVTQGATGDLLELYCGNGNFSLALARNFERVLATEIAKPSVAAAQYNIAANNIDNVQIIRMSAEEFTQAMQGVREFNRLKGIDLGSYNCETIFVDPPRSGLDHETVKLVQAYPRILYISCNPETLCANLEQLQHTHKISRLALFDQFPYTHHMECGVLLEKRH
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RPRMA_DANRE
Sequence: MNSTFNQTDSGIFSNRTEENLLCCNFSSVVTDNGFAAAAPDERSLFIMRIVQIAVMCVLSLTVVFGIFFLGCNLLIKSEGMINFLVTDRRPSKEVEAVIVGAY
What is the function of this protein?
May be involved in the regulation of p53-dependent G2 arrest of the cell cycle.
What are the official names of this protein?
Protein reprimo A.
What is the protein family that this protein belongs to?
Belongs to the reprimo family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass membrane protein.
Protein: RS15_YERPS
Sequence: MSLSVEAKAKIVADFGRGTNDTGSSEVQVALLTAQINHLQGHFSEHKKDHHSRRGLLRMVSTRRKLLDYLKRQDVARYASLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: THIM_CAMLR
Sequence: MYIEKIRKVKPLIHHITNYVTVNDCANASIAIGASPIMADFIQEQEEFSKICNCLVLNTGTINERVANSMYESAKFYGNLNKAIVLDPVALGVSMARDAINLKLLNSYKISIIKANASEIASVIGLDGKAKGTDNTFVVNDHFLDKACEYAKGHNRILVVSGEVDFIISSEKIAKIYNGSIMATKITGAGCMCASMCGVFAGVIEDKFQASLQAMLSFDIACEMAEEISNGSGSFRVNLIDALSNLNDEDVKKRAKYEII
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: ATPB_COFAR
Sequence: MKINPTTSGSGVSTLEKKNMGRIVQIIGPVLDVAFPAGKMPNIYNALVVKGRDTVGQPINVTCEVQQLLGNNRVRAVAMSSTDGLTRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGAVDTRTTSPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINKENIAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDSLPEQAFYLVGNIDEATAKAMNLEMENNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: KRT84_HUMAN
Sequence: MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSGGRSSSVRFVSTTTSCRTKY
What are the official names of this protein?
Keratin, type II cuticular Hb4, Keratin-84, K84, Type II hair keratin Hb4, Type-II keratin Kb24.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: Y1864_ARATH
Sequence: MCLLRHLLPIWVLLGFFFFSTATKSQESSVVYVSGASPEIPISQASPRMGAQSPGPPIVKVVLRQDLNKKILIALIVSSSLLCVTVMFLVYLLLWRYRNMKNSFTGIKRKSDSVKSVTTKPTVHKIDSVRKGTIPVYEYQLLESATNKFSDSNVLSRGGRGCLYRACLDEKSSVTVKKLDGGGETDIEKQFETEVDWLAKIRHQNIVSLLGFCVYRQTSCIVYELMQNGSLESQLHGPSQGSGLTWQLRMKIAVDIARGLEYLHEHCHPPVVHRDLKSSSILLDSDFNAKISDFGFATVLTTQNKNLIHKASEDLLDGKVTDKNDVYSFGVILLELLLGKKSVEKPSSEPESIVTWAVPKLSDRANLPNILDPAIKGTMDLKHLYQVAAVAVLCVQPEPSYRPLITDVLHSLIPLLPVELGGSLRIL
What are the official names of this protein?
Probable receptor-like protein kinase At1g80640.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LAT1_RAT
Sequence: MAVAGAKRRAVAAPATTAAEEERQAREKMLEARRGDGADPEGEGVTLQRNITLINGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDIGQGDASNLHQKLSFEGTNLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSILSMIHPQLLTPVPSLVFTCVMTLMYAFSRDIFSIINFFSFFNWLCVALAIIGMMWLRFKKPELERPIKVNLALPVFFILACLFLIAVSFWKTPLECGIGFAIILSGLPVYFFGVWWKNKPKWILQVIFSVTVLCQKLMQVVPQET
What is the function of this protein?
The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, L-DOPA, histidine, methionine, valine and alanine (By similarity).  The heterodimer with SLC3A2 mediates the uptake of leucine, isoleucine and tryptophan (PubMed:9726963, PubMed:11311135, PubMed:12614332, PubMed:15980244).  Functions as an amino acid exchanger (By similarity).  May play a role in the transport of L-DOPA across the blood-brain barrier (By similarity).  May act as the major transporter of tyrosine in fibroblasts (By similarity).  May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier (Probable).  Can mediate the transport of thyroid hormones diiodothyronine (T2), triiodothyronine (T3) and thyroxine (T4) across the cell membrane.  When associated with LAPTM4B, the heterodimer formed by SLC3A2 and SLC7A5 is recruited to lysosomes to promote leucine uptake into these organelles, and thereby mediates mTORC1 activation.  Involved in the uptake of toxic methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes.  Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the membrane (By similarity).
What are the official names of this protein?
Large neutral amino acids transporter small subunit 1, 4F2 light chain, 4F2 LC, 4F2LC, Integral membrane protein E16, Protein TA1, L-type amino acid transporter 1, LAT-1, Solute carrier family 7 member 5.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Located to the plasma membrane by SLC3A2/4F2hc. Localized to the apical membrane of placental syncytiotrophoblastic cells. Recruited to lysosomes by LAPTM4B (By similarity). Expressed in both luminal and abluminal membranes of brain capillary endothelial cells (By similarity).
Protein: XYNA_PENSI
Sequence: QASVSIDAKFKAHGKKYLGTIGDQYTLTKNTKNPAIIKADFGQLTPENSMKWDATEPNRGQFTFSGSDYLVNFAQSNGKLIRGHTLVWHSQLPGWVSSITDKNTLISVLKNHITTVMTRYKGKIYAWDVLNEIFNEDGSLRNSVFYNVIGEDYVRIAFETARSVDPNAKLYINDYNLDSAGYSKVNGMVSHVKKWLAAGIPIDGIGSQTHLGAGAGSAVAGALNALASAGTKEIAITELDIAGASSTDYVNVVNACLNQAKCVGITVWGVADPDSWRSSSSPLLFDGNYNPKAAYNAIANAL
What are the official names of this protein?
Endo-1,4-beta-xylanase, Xylanase, 1,4-beta-D-xylan xylanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NIFK_METBA
Sequence: MLDYTPCEEVTREAVTINPAKTCQPIGAVYAALGVHNCMPHSHGSQGCLSYLRMCLSRHYREAALATTSSFSEGTAVFGVSANLKEALVNLTTIYKPEVIAIHTTCVAETIGDDVGVILEDVEAEELIDPSIKICAASTPSYVGSHITGYDNMVKSFVTTFTKKSKPNGKLNIIPGFVEPGDIREIKRILSIMEISSIVFPDTTDVFGAPLTGEPGMYPKGGTPIGDIEDSANSVGTIALCRMAGGSAAKILEGRYKVPAKIGPTPIGIRNTDRFVMNAAKLANVAIPPELEDERGRLVDMMTDAHPHYHGKKVAIYGDPDILTGLTSLVMEMGMEPVVVLTGTKSSEFEKEVEGLIGPEHPEADVISGGDMFTLHQIIKRKPVDLLIGNTYGKFISRAEDVPLVRVGFPIMDRANLHYFPIMGYAGAARLVERIANTLLDRKDRDAPDWLLETIQ
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: PG077_VACCC
Sequence: MAEFEDQLVFNSISARALKAYFTAKINEMVDELVTRKCPQKKKSQAKKPEVRIPVDLVKSSFVKKFGLCNYGGILISLINSLVENNFFTKDGKLDDTGKKELVLTDVEKRILNTIDKSSPLYIDISDVKVLAARLKRSATQFNFNGHTYHLENDKIEDLINQLVKDESIQLDEKSSIKDSMYVIPDELIDVLKTRLFRSPQVKDNIISRTRLYDYFTRVTKRDESSIYVILKDPRIASILSLETVKMGAFMYTKHSMLTNAISSRVDRYSKKFQESFYEDIAEFVKENERVNVSRVVECLTVPNITISSNAE
What is the function of this protein?
DNA-binding protein which binds to the hairpin form of the viral telomeric sequence.  Required for the production of mature virions (MV).
What are the official names of this protein?
Telomere-binding protein OPG077, Telomere-binding protein I1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG077 family.
Protein: IF2_SHEPW
Sequence: MADTTVDKLAKEVGKSADRLVEQFSQAGIKKSANDTVSESEKQQLLDFLKKQHGGDAAPQKMTLQRKSVSTLSVAGSGGQSKDVKVEVRKKRTFVKRDEAAEAELAAAAKAEEEAKAAAAKAEAEAKAKADAEAKQKADAEAKAKAEKAAKAKSEKQEAAPAQTADEKAAKDEADKLQAAKDEVAKAKADAEAAAATEEARRLAEENAKRWADEEKARKEAEKTGDHHVTTSTEARAAEDTADANAEKRGRRPRKPSANAGNNANSNSNAGSGRPGGKGKRGKDNRRDNRNSRNSRNARSVAPESMDQAFNKSAVVVKAEVSIGETVSVSELASKMSVKATEIIKQMMKMGSMVTINQVLDQETAQLVAEEMGHKVILTRENELEHQVLADRNGDVKVEPRAPVVTIMGHVDHGKTSLLDYIRRAKVASGEAGGITQHIGAYHVETGNGMITFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTIEAIQHAKAGGVPLIVAVNKIDKPEADPERVKSELSQHGVMSEDWGGENMFVHVSAKSGEGIDELLEGILLESEVLELKAVREGMAAGVVVESKLDKGRGPVATVLVQEGTLKQGDIVLCGLEYGKVRAMKDENGKAITEAGPSIPVEILGLSGVPSAGDEATVVRDERKAREVALYRQGKFRDVKLARQQKSKLENMFANMVEGEVQELNLVLKADVQGSLEAIADSLNKLSTDEVKVNIIARGVGGLTETDATLAAASNAIMVGFNVRADAQARKVVDSESVDLRYYSIIYQLIDEVRDAMGGMLAPEFRQEIIGLAEVRDVFKSPKIGAIAGCMVTEGTIKRSAPIRVLRENVVIYEGELESLRRFKDDVSDVRNGMECGIGVKNYNDVRVGDQIEVFETVEIARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.