PharMolix/UniProtQA huggingface dataset:
Protein: PE13A_LITPE
Sequence: DAQEKRQPWLPFV
What are the official names of this protein?
Peroniin-1.3a.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Peroniin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PDXT_SYNAS
Sequence: MIYREDSRRNTIGVLDLQGGVCEHLEHLERLGIACKRVKEPLDFEGVAGLILPGGESTCLSRLIRIFHLEGCILDAFQKGMKIWGTCAGAILLATGILGERPHLGLIDMDIERNGFGSQLDSFCIEAALPELSADPVPLTFIRAPKIRRVGSDVRILLQLQDYIVAAENDRVLVTVFHPELTPCIVFHKHFVHKCGICCTPEDDLADSDAQWNSRSWMRLAPHV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: Y2309_ACIAD
Sequence: MHCDIYRSSKKDEMYLYIARPDYPNDDVEGQDPLENVPEGIRTVFGKPTFVMHLELSQSRKLARVNVLHVLDSLQTKGFFIQMPPEGFINPSDEPEGLRGA
What are the official names of this protein?
YcgL domain-containing protein ACIAD2309.
Protein: NRDR_ANASK
Sequence: MRCPYCGHLEDRVVDSRETQDGQATRRRRACLSCERRFTTYERIEDVLPQVVKKDGRREAFDRAKIVEGVATACQKRPVSTEQVEALVSAVERQVQELGEREIRTTVIGEAVMQRLRTLDEVAYVRFASVYRAFRDVGEFMTELAGLARKDGEER
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: HSLO_PROM1
Sequence: MTDSLVRATAAKGGIRLVAVSTTESTKEAKERHSLSYLTSAIVGRAMSASLLLASSMKVNHGRVTLRISSNGPLKGLTIDAGRDGSVRGYVGDPSLELDLIKNKSNHYTFDFKKATGIGYLHVIRDDGKGEPHNSTVELINGGIGEDIASYLLHSEQTPSAVFVGERINQDGIVCSGGLLAQILPKAERDYSLIDLLEDRCKEINSFSELLNKKGNNLISLIEEIFPDLDQSPSDIISTSQEVRFKCRCSRERSLSALKILGKDELQKMIKEDGKAELTCQFCKNVYLVKEDELISLID
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_VARPS
Sequence: MKAIYDLPAPAKLNLFLHITGRREDGYHLLQSVFMLIDWCDTLHVELRSDGQLSREDLTTELPPDDLVLRAARALQAHAAPGQGAHIGIAKQVPAQAGMGGGSSDAATCLLALNRLWGLDLPLSRLAEIGVQLGADVPFFLGGRNAWVEGIGEKIRPVDIPSARFVVAKPPQGLDTKLIFSAPDLQRATPVAIISGFAADSEQLEAPNPESSAFKVFDFGHNDLQPVAQRLCPAVTDAIEWLGAQGLKARMTGSGSSVFAKMPQGPQEAELAKAPPGWQVRQCSNLAVHPLWGWAT
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CH601_PROM3
Sequence: MAKRIIYNEQARRALERGIDILAESVAVTLGPKGRNVVLEKKFGAPQIINDGVTIAKEIELEDHIENTGVALIRQAASKTNDAAGDGTTTATVLAHAMVKAGLRNVAAGANAISLKKGIDKASDFLVSKIEELAKPISDSNAIAQCGTIAAGNDEEVGQMIADAMDKVGKEGVISLEEGKSMTTELEVTEGMRFDKGYISPYFATDTERMEAVLDEPYILLTDKKIGLVQDLVPVLEQIARTGKPLLIIAEDIEKEALATLVVNRLRGVLNVAAVKAPGFGDRRKAMLEDMAVLTNGQLITEDAGLKLDNAKLEMLGTARRVTINKDTTTIVAEGNETAVKGRCEQIKKQMDETDSTYDKEKLQERLAKLAGGVAVVKVGAATETEMKDKKLRLEDAINATKAAVEEGIVPGGGTTLTHLAADLQKWANSNLSGEELIGANIVEASLAAPLMRIAENAGANGAVVAENVKSRPISDGYNAATGDYIDMLAAGIVDPAKVTRSGLQNAASIAGMVLTTECIVADLPEKKEAAPAGGGGMGGDFDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_CHLPB
Sequence: MSRIGKMPIKLAEQAKIEIKDNVISVSGPKGNLEQRLVPEVTVDIADGQVAVTRIDDSKRSRAMHGLYRMLISNMLEGVTSGFSKKLLINGVGFRAEKKAEFLALTLGYSHMIYFKAPEEIAIECPDPTSIVVSGIDKALVGQVAAKIRSFRKPEPYRGKGIRYSDEFVRRKEGKTAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: FRDB_MYCTO
Sequence: MMDRIVMEVSRYRPEIESAPTFQAYEVPLTREWAVLDGLTYIKDHLDGTLSFRWSCRMGICGSSGMTINGDPKLACATFLADYLPGPVRVEPMRNFPVIRDLVVDISDFMAKLPSVKPWLVRHDEPPVEDGEYRQTPAELDAFKQFSMCINCMLCYSACPVYALDPDFLGPAAIALGQRYNLDSRDQGAADRRDVLAAADGAWACTLVGECSTACPKGVDPAGAIQRYKLTAATHALKKLLFPWGGG
What are the official names of this protein?
Fumarate reductase iron-sulfur subunit, Quinol-fumarate reductase iron-sulfur subunit, QFR iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YBEY_VEREI
Sequence: MPLKPLALSLQWGRFDAAAAQRSALPRHLIRRWIRHALTTDAEITVRIVGADEGRQLNRTYRNKDYATNVLTFVYSQAPLVTADLLLCAPVIEREAQQQGKHLQAHYAHMLVHGTLHAQGWDHEGSADADAMQARETQIMQALGFADPYARQPG
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_WIGBR
Sequence: MAVQKNKPTRSKRGMRRSHDKINIHKFSVDKVSGEIHIRHCLTKSGFYCGKKVLNKKNK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RPOZ_MARN8
Sequence: MARVTVEDCLENVDNRFQLVMLATKRARQIATKGAEPMVAEENDKPTVIALREIAEGKVTRDLLLEEDDD
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: EX7S_LISMH
Sequence: MATKKKTFEEAIAELETIVEALENGSASLEDSLDMYQKGIELTKLCQDKLQSAEKRMAKVVTDAGEEIPFEADGE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYML7_MELLF
Sequence: GLPTCGETCFKGKCYTPGCSCSYPICKKN
What is the function of this protein?
Probably participates in a plant defense mechanism (Potential).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (PubMed:26322745).  In vitro, displays cytotoxicity against cultured cells but no hemolytic activity towards fresh erythrocytes (PubMed:26322745).  Not active against Gram-negative bacterium E. coli ATCC 25922 or Gram-positive bacterium S. aureus ATCC 25923 up to a concentration of 64 uM (PubMed:26322745).
What are the official names of this protein?
Cyclotide mela-7.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebuis subfamily.
Protein: EFTU_GLOC7
Sequence: MARAKFERTKPHVNIGTIGHVDHGKTTLTAAITMALAAQGKAKARKYADIDAAPEEKARGITINTAHVEYETDDRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLAKQVGVPNLVVFLNKEDMVDDEELLELVELEVRELLSEYEFPGDDIPIVKGSALKAVEALTDTPTIKKGDNDWVDKILALMDEVDAYIPTPERDIDKPFLMAIEDVFSISGRGTVATGRIERGKIKAGETVEIVGIKEKTKSTTVTGVEMFQKTLEEGLAGDNVGLLLRGVQKEEIERGMVIAKPGSIKPHTQFEGEVYVLTKEEGGRHTPFFKNYRPQFYVRTTDVTGTIVDYTADDGSAVEMVMPGDRIKMTVELINPIAIEQGMRFAIREGGRTIGAGVVSKIIQ
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK9_PORPU
Sequence: MSKKIIQVVLKENIQKLGKSNDVVKVATGYARNFLIPNKMASVATVGMLNQQKLYAAIKEKKIIFAKENARKTQQLLEEIQKFSISKKTGDGETIFGSVTEKEISQIIKNTTNVDIDKQNILIPEIKTIGLYNIEIKLFNQVTANIQLQVLPESN
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RPOB_STRR6
Sequence: MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHGLKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVRNTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVGRYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKIVYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYFLNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIVWLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQYDGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIADGPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDTKLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQEVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: COFG_METPE
Sequence: MHQGVITFSRNVFLPLTTVCQNHCGYCSFWTPIQKGCIMGREQVIETLRLGAGAGCTEALFTFGERPEMVPGFSEHLAAIGYSSILDYCYDLCKEALRFGILPHTNAGVLSTGEMERLREVNASMGLMLETTADVPAHQGSIGKSPAERLSMIARAGKLRIPFTTGILLGIGETTRDREESLEAIADLQREYGHIQEVIVQNFCPKEGTPMADVTPITTETFCETVRMARAILPEEVAVQVAPNLADAGVLVGCGANDLGGISPVTIDYVNPEHPWPAIDRLTEVAGDAVLRERLCIYPQYITQGWYPPSMEPLIRSLSIKIQERSL
What is the function of this protein?
Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8-hydroxy-5-deazariboflavin from 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil.
What are the official names of this protein?
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, FO synthase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. CofG family.
Protein: CST9_HUMAN
Sequence: MSSPQRRKAMPWALSLLLMGFQLLVTYAWCSEEEMGGNNKIVQDPMFLATVEFALNTFNVQSKEEHAYRLLRVLSSWREDSMDRKWRGKMVFSMNLQLRQTVCRKFEDDIDNCPFQESLELNNVRQGISFPQVHSCGCCMGCGVGTGAADKAIPRDKGK
What is the function of this protein?
May be involved in testis development (By similarity).  May play a role in hematopoietic differentiation or inflammation (PubMed:12535658).  Has immunomodulatory and antimicrobial functions against Francisella tularensis, a Gram-negative bacteria (PubMed:23922243).
What are the official names of this protein?
Cystatin-9, Cystatin-like molecule.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted. Note=May be targeted through the Golgi via the secretory pathway.
Protein: DAPE_PSEAE
Sequence: MTASSPSLSPTLELACELIRRPSVTPLDADCQALMMRRLEAAGFALEPMRIEEVDNFWARRGGDGPVLCFAGHTDVVPTGPLQAWQHQPFDALIDDQGMLCGRGAADMKGSLASMIVAVERFVADHPEHKGAIAFLITSDEEGPAHHGTKAVVERLAARGERLDWCIVGEPSSTSLVGDVVKNGRRGSLGAKLTIRGVQGHVAYPHLAKNPIHLAAPALAELAAEHWDDGNAFFPPTSFQVSNLNSGTGATNVIPGELTALFNFRFSTESTVEGLQKRVEAILDKHGLDWHVEWALSGLPFLTEPGELLDAVAASIRAVTGRETQPSTSGGTSDGRFIATMGTQVVELGPVNATIHQVNERVLASDLELLTEIYYQTLVRLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MURA_PSESM
Sequence: MDKLIITGGVRLDGEIRISGAKNSALPILAATLLADGPVTVQNLPHLHDITTMIELFGRMGIEPVIDEKLSVEIDPRTIKTLIAPYELVKTMRASILVLGPMVARFGEAEVALPGGCAIGSRPVDLHIRGLEAMGAIIDVEGGYIKAKAPEGGLRGAHFFFDTVSVTGTENIMMAASLANGRSVLENAAREPEVVDLANFLIAMGAKIHGAGTDTITIDGVKRLGSATYKVMPDRIETGTYLVAAAVTGGRVKVKDTDPTILEAVLLKLQEAGAEVTTGEDWIELNMHGKRPKAVNVRTAPYPAFPTDMQAQFISLNAIAEGTGAVIETIFENRFMHVYEMHRMGAQIQVEGNTAIVTGTEVLKGAPVMATDLRASASLVISALVAQGDTLIDRIYHIDRGYECIEEKLQMLGAKIRRVPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_PARP8
Sequence: MSQIQTAPLPVMPSQAAAAADAAASRWKVADVAALYELPFNDLLFRAQQVHREHFDANTVQLSTLLSIKTGGCEEDCAYCPQSVHHETGLKAEKLMEVEEVLAAARVAKENGATRFCMGAAWRNPKDRHLEPIKDMIRGVKSMGLETCVTLGMLEAHQAQALREAGLDYYNHNLDTSPEFYGQIISTRTYQDRLDTLEHVRDAGINVCCGGIVGLGESRRERAGLIAQLANMEPYPESVPINNLVQVEGTPLTGTEALDPFEFVRTIAVARITMPRAMVRLSAGREQMDEALQAMCFLAGANSIFYGDQLLTTSNPQAEADRKLLARLGIRAEAAQQMPAERECSHGCEGH
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MT1A_ORYSI
Sequence: MSCSCGSSCSCGSNCSCGKKYPDLEEKSSSTKATVVLGVAPEKKAQQFEAAAESGETAHGCSCGSSCRCNPCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable).  May be involved in ROS homeostasis.  May act as reactive oxygen species (ROS) scavenger in response to salt stress (PubMed:23385446).
What are the official names of this protein?
Metallothionein-like protein 1A, Class I metallothionein-like protein 1A, OsMT-I-1a, OsMT1a.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: EX7S_XANOM
Sequence: MAKKSLNETSPVARFEQSLEELEQLVQKMEVGDLSLEQSLTAYERGIGLYRDCQQALEQAELRVRLLTDPARPELAQAFEPPSLDG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_BART1
Sequence: MNIHEYQAKRLLHEYGAPIANGVAVYSIEQAEKWAKKLPGPLYVVKSQIHAGGRGKGQFKELGPDAKGGVRLAQSVEEVVANVQEMLGKTLVTKQTGPEGKQVNRLYIEDGADIERELYLSLLVDRSVGRIAFVVSTEGGMDIETVAEETPEKIFTLPIDVTEGVTSADCARLCDALELHDSAREDGEKLFPILYKAFCEKDMSLLEINPLIVMKDGHLRVLDAKVSFDNNALFRHPDILELRDLSEEDPKEIEASKHDLAYVALEGTIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPNVKGILVNIFGGIMRCDVIAEGVVAAVREVGLKVPLVVRLEGTNVEQGKAIINDSGLNVIPADDLDDAAQKIVAAVKGA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: Y585_BUCAI
Sequence: MLHNLLLNPNQSNKTHPNTIDIYTDAIKTMFETNKNQTVSKKNDQNTYDLEDENKLIDLENSYKKSLILLNILQKKIEQNILEKYNLEKNNNNITDNSDNEIIQNTLIKKNS
What are the official names of this protein?
Uncharacterized protein BU585, yba4.
What is the protein family that this protein belongs to?
To Buchnera BUsg564.
Protein: HEM6_SALSV
Sequence: MKPDAHHVKQFLLRLQDDICQKLSAADGANFVEDSWRREAGGGGRSRVLRNGGIFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGDDVYPRYKKWCDDYFFLKHRNEQRGVGGLFFDDLNTPDFDHCFAFMQAVGNGYTQAYLPIVERRKAMVWGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDWQPEAGSPEAALSEFIQVRDWV
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_CHLMU
Sequence: MVIRLFENDKQLEVFFSSLDKKKKYLLALSGGSDSLLLMYLLRSRGISFTAVHVDYGWRETSYQEACDLASLCEREQIPFILDRQEVANPMDFSDIENIARQYRYELFYRLCKERLFAGVFLGHHADDQAETILKRVFEGAHLGNLKGMARYGTYKGITLLRPLLHITKRQIVEALDNYRIEYVQDATNADERFLRARMREQLFPYLQEIFGKNIRQPLLFLAEDSAELREYLDQQAAPFLSQVIDNEIGQFLPVGQELLQTAFLTKWVCKQFFFKQGLVASKGFLQTVYDHLVRRSEARLRLRNRTVLVKARGVIIESIY
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAII_SHIDS
Sequence: MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG
What are the official names of this protein?
UPF0178 protein YaiI.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: ENO_CLOB8
Sequence: MKDYLEIVDVVARQILDSRCFPTVEVEIYLEDGTIGRAAVPSGASTGMYEAVELRDGDKDKFLGKGVLNAIRNVNEIIAEELIGCNVFEQTYIDKMLIELDGTNNKSKLGANAILGVSLAVANAAANSLDMPLYRYIGGVNSKVLPVPMMNILNGGSHADNSVDLQEFMIMPAGAPTFSEALRMCAEVYHTLKKILNDKGYSTGIGDEGGFAPNLKSNQEALDVIIEAIGKAGYKAGEEIFIAIDAASSEYYKDGKYVLEHEGRTLTSAEMVDFFEDWVNKYPIISIEDGMAEEDWEGWKLITERLGKKVQLVGDDLFVTNTERLEKGIDLGVANSILIKLNQIGTLTETLNAIEMANRAGYTAVVSHRSGETEDTTIADLVVAVNAGQIKTGAPARSERVAKYNQLLRIEEELNDVAEYRGRKAFFNIK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: AP3M_ASHGO
Sequence: MYTSIYITDSKKNLVFEYLLTSQAPTFQQLCSKIAGRDAAMDAMVAISKDMSLYRQAVGPEKLWYWALCQACGDPLEPQMFLAQYHQVLIEYFDKEALTVKKLVNNADRLALLLHAMLDAGEVAVTDSNRLRQLVPLRNDLSTILNSATKTLANTVKYADSKQLFGAPVATGKVEAGQTVPWRTADCRYVNNEIYVDLVETVNATLRQKGSSLTLINGSLSGKIDVKCYLSGNPTVQLKLRTSGHPLDNSALHRCVELGEAGVATMNFVPPDGRFTLAEYAIDLSAISQAARRLTNLGLVTVSLASGLGQHRDEFEIKVIIGNSTQVAAIEDLRITVYFPDISDAAKIKILRTTHGGWESDLSRVRGVWAFDKQTAVGSVPVLRGCVENPESTPHAPPVFPSHLAVSYSHVGQLPSGIRVDTIALSDLPPGSKPFKGVKYTSRAGDYIVRA
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole (By similarity).
What are the official names of this protein?
AP-3 complex subunit mu, AP-3 adaptor complex mu3A subunit, Adaptor-related protein complex 3 subunit mu, Mu-adaptin 3A, Mu3-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.