PharMolix/UniProtQA huggingface dataset:
Protein: PCAQ_AGRFC
Sequence: MVDQRIKFRHLQTFVEVARQKSVIRAAEILHVSQPAVTKTIRELEDVLGVSLLEREGRGIRISRYGEVFLRHAGATMTALRQAVDSVSQEAARAGPPVRVGALPTVSVRIMPKAMSGFLAEKTGSPVKIVTGENAVLLEQLRVGDLDLVVGRLAAPQKMAGFSFEHLYSEKVRFVVRAGHPLLSPGLSVFDHLHEYPVLMPTRQSVIGPVVEQFLIANGVPALPIRIETVSDAFGRAFLRTSDAIWIISEGVVAADVADGILAILPVETGDTSGPVGLTVRADTQPSLPLSLLMQAIREAAGELFDGRTEG
What is the function of this protein?
Activates transcription of the pcaDCHGB operon for the catabolism of the phenolic compound protocatechuate.
What are the official names of this protein?
HTH-type transcriptional regulator PcaQ, Pca operon transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: GLND_ECO57
Sequence: MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVATNLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGIYSTTLRQLRHARRHLQQPLCNIPQARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVNVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEVLHQIWSRCRANYFVRHSPNQLAWHARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHFTVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRLTEALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: CSP2_STRM6
Sequence: MKNTVKLEQFVALKEKELQKIKGGEMRKPDGALFNLFRRR
What is the function of this protein?
Acts as a pheromone, induces cells to develop competence for genetic transformation.
What are the official names of this protein?
Competence-stimulating peptide, CSP.
What is the protein family that this protein belongs to?
Belongs to the ComC family.
What are the subcellular locations of this protein?
Secreted.
Protein: IHFA_THIDA
Sequence: MTTLTKADLAELLFEKVGLNKREAKDVVESFFDEIRLALEKGDIVKLSGFGNFQCREKPQRPGRNPKTGEEMPISARRVVTFHASQKLKSQVEGARIGTPSQE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RL15_STRAW
Sequence: MAENNPLKIHNLRPAPGAKTAKTRVGRGEASKGKTAGRGTKGTKARYQVPERFEGGQMPLHMRLPKLKGFKNPFRTEYQVVNLDKLTALYPEGGEVTVEGLVAKGAVRKNSLVKVLGQGEISVALQVTVDAVSGSAKEKITAAGGTVTELV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: NOS2_CANLF
Sequence: MACPWKFLFRAKFHQYGMKEEKDINNNVEKPPGATPSPSTQDDLKNHKHHNDSPQPLTETVQKLPESLDKLHATPLSRPQHVRIKNWGNGMTFQDTLHHKAKGDLACKSKSCLGAIMNPKSLTREPRDKPTPPDELLPQAIEFVNQYYSSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAKEMFEHICRHLRYASNNGNIRSAITVFPQRTDGKHDFRVWNAQLIRYAGYQMPDGTILGDPASVEFTQLCIDLGWKPKYGRFDVVPLVLQADGQDPEFFEIPPDLVLEVPMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDRAVIEINVAVLHSFQKQNVTIMDHHSAAESFMKYMQSEYRSRGGCPADWIWLVPPISGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQDEKRRPQRRKIQLKVLVKAVLFASMLMRKTMASRVRVTILFATETGKSETLARDLGALFSCAFHPKVLCMDEYKLSHLEEEQLLLVVTSTFGNGDSPGNGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDHKLSHLGASQLTPGGEGDELNGKEEAFRCWAVQTFKAACDTSDVRGKHCIQIPRLYTSNVTWDPHHYRLLQDSQPLDLNKALSKMHAKNVFTLRLKSQRNLQSPISNRTTLQVELSCEDSQELSYLPGEHLGVFPGNQLALVQGILERVVYSPAPLQPVHLETLSERGSYWVRNNRLPPCSLSQALTYFLDITTPPTHLLLRKLAQLAHQYAERHRLEILCHPSEYNKWKLTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRYYSISSSRDCTPMEVHLTVAVLVYPTRDGQGPLHHGVCSTWLSNLKPQDPVPCFVRSAGNFKLPEDPSRPCILIGPGTGIAPFRSFWQQRLHDIKHKGLRGSRMTLVFGCRRPDEDHLYREEMLEMAQSGVLHEVHTAYSRLPGQPKVYVQDILRQQLASQVLRMLHEEQGHLYVCGDVRMARDVAHTLKHLVAAKLSLSEEQVEDYFFQLKSQKRYHEDIFGAVFPYEVKKDGAAKQPSDPRVPAAHGRS
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.  In macrophages, NO mediates tumoricidal and bactericidal actions.  Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2.  As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM.  Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8.
What are the official names of this protein?
Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Localizes as discrete foci scattered throughout the cytosol and in the presence of SPSB1 and SPSB4, exhibits a more diffuse cytosolic localization.
Protein: PEL1_ARATH
Sequence: MKIVRRDFVRNGPGSVKMVAEDSDDLWYAYNLIAVGDSVMAVTFRKVQREIPGGGRDSERVKLKLEVQVEEVDYDKDGSVLRIRGKNILENEHVKIGAFHTLELELKRPFVLRKEMWDSMALDTLKQASDPAASADLAVVLMQEGLAQIFLVGRSVTSSRARIETSIPRKHGPAIAGYESALKKFFENVLQAFVKHVDFSVVRCAVVASPGFTKDQFHRHLLLEAERRQLRPIIENKSRIILVHTNSGYRHSLGEVLHAPNVMNMIKDTKAAKEVKALNDFHNMLSTEPDRACYGPKHVEVANERMAIQTLLITDELFRNSDVKTRKKYVNLVESVKDSGGDAFIFSAMHVSGEQLAQLTGIAALLRFPLPELEDIEM
What is the function of this protein?
Required for normal chromosome segregation during cell division and genomic stability (By similarity).  May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.  May have ribonuclease activity (Potential).
What are the official names of this protein?
Protein PELOTA 1, AtPelota1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: EIF3A_COCIM
Sequence: MPPIPHVRPENVLRRAEELIAVGQPAAALSVLHEHVTSKRSRSSPIASLEPVMLLFVELCVDLRKGKSAKDGLYQYKNIAQNTNVGTIEMVLKKFIELAEQKVTEAQAKADEIQSSLESAAPTSNVEDLDAIETPETILLATVSGEQSRDRTDRAVVTPWLKFLWETYRTVLEILKNNARLEVMYQATALQAFQFCLKYTRKTEFRRLCELLRNHVQNAAKYSAQMHAINLSDPDTLQRHLDTRFQQLNVAVELELWQEGFRSVEDIHTLLNLSKRQPKNIMMANYYEKLTKIFMVSDNYLFHAAAWNRYYNLLRQSAIALAAGQGSKKDSPSVTEADMTKAASFVLLSALSIPVISTSRSRGALVDVDEVRKNKNTRLTNLLGMPQPPTRASLFKDALNKGLLSRCRPEIRDLYNILEVDFHPLSICKKISPILKEIGADPEMEKYVLPLQQVILTRLFQQLSQVYESVELKFVHELAHFPEPFQVTSSMIEKFIMNGCKKGDLAIRVDHVSGVLTFESDIFSSAKALHPGSAAGSAESEVGSVQRLQSTPAEIARSQLARLAKTLHVTCMYVDPSYNQARIKAKEAAHARARAGAAKEHEETLTRRAIIEKRKEALSDALQKKQREEENRKRARNQQLQEAEQQRLLDEHRERERKRMKDEQDRIRQQELKKQLEELKTGVKGIDVNQIDLEELDSNRLRAIKLAQLEKEKNDLNEKIRITSKRIDHLERAFRREELKHLPEDYETQKKQDLETYEQTKEETLKAARQKHKEDVALKHRLSRLVPYFNDFKKSVTEKRHEEFERRRKAADREFEQKKKQRIKEVHERIRRERAEREAEEQRRREEEERIAREEQERIAKEEERRRALAEEKAAREEQRRKLDEQAIRQRQREEEAEQRRAARKAGLAEPRGPAREASPERTAPRLNLAGRTGTSWRDRQAAKAAASAGEQPAAAQEATPAPPAKAGSYLPPHLRATRDGPSDSRDLSHARESAAPPRQFSRSPVPPSGAPSSQEKPGPWRPRFKQQQ
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGF23_RAT
Sequence: MLGACLRLLVGALCTVCSLGTARAYSDTSPLLGSNWGSLTHLYTATARNSYHLQIHRDGHVDGTPHQTIYSALMITSEDAGSVVIIGAMTRRFLCMDLRGNIFGSYHFSPENCRFRQWTLENGYDVYLSPKHHYLVSLGRSKRIFQPGTNPPPFSQFLARRNEVPLLHFYTARPRRHTRSAEDPPERDPLNVLKPRPRATPIPVSCSRELPSAEEGGPAASDPLGVLRRGRGDARRGAGGTDRCRPFPRFV
What is the function of this protein?
Regulator of phosphate homeostasis (By similarity).  Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity).  Regulator of vitamin-D metabolism (By similarity).  Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity).  Acts directly on the parathyroid to decrease PTH secretion (PubMed:17992255).  Up-regulates EGR1 expression in the presence of KL (PubMed:17086194).
What are the official names of this protein?
Fibroblast growth factor 23, FGF-23.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Note=Secretion is dependent on O-glycosylation.
Protein: TSAD_SYNSC
Sequence: MHAVLALETSCDESAAAVLRRHADGRIDVLASRIASQVEEHARWGGVVPEIASRRHVEALPGLVEAVVDEAGVTLGQLDAIAATITPGLAGALMVASVTGRTLAALHQRPFLGVHHLEGHLASVMLGDVPQQAPYLVLLVSGGHTELILVAEDGGMTRLGRSHDDAAGEAFDKVARLLGLGYPGGPAIQAVAETGDATRFRLPKGRISLPGGGFHPYDFSFSGLKTAMLRTVETLRQTTDSLPLADLAASFEQVVADVLVQRSLRCAADHGVQQLVMVGGVAANRRLRQSMLEQGNQRGIAVSIAPLAFCTDNAAMIGAAALMRLGQNAACTSFESGVAARWPLDQANALYTPDPPF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHBDL_MIMIV
Sequence: MRYVTYIVLLILVVIFFSPLNFFNTNSEIINYLIRTFYHANLQHLLANSFSFYMLSFLEDVMGHAKFAFCIIFIWILSSMLLLAEHTAFPSRKVYTVGFSGVIFGLIVVYLMSLGKNRGLSIAGLVLSIIPQFFVSGISYEGHICGMIAGFVYVVLFPLPKGSVDNQVAMF
What is the function of this protein?
Probable serine protease.
What are the official names of this protein?
Putative rhomboid protein L523.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PIP1_DROME
Sequence: MMSAGGTYISTASVEVPQALQDGEKFIRWDDDSGTGTPVTMRVDAKGFFLYWVDQNNELDILDIATIRDVRTGQYAKRPKDNKLRQIVTLGPQDTLEEKTVTVCHGSDFVNMTFVNFCCTRRDIAQLWTDGLIKLAYSLAQLNGSAIMFLQKAHTKLCLQVDKSGRIPVKNIIKLFAQNKEDRKRVEKALDVTGLPSGKVDSISVSKFQFEDFYNLYKYLTQRSEVERLFDSIVGNSKRKCMSIAQLVEFLNKTQRDPRLNEILYPYANPARAKELIQQYEPNKFNAQKGQLSLDGFLRYLMGDDNPIMAPSKLDLCDDMDQPMSHYFINSSHNTYLTGHQLTGKSSVEIYRQCLLAGCRCVELDFWNGRTEEPVIVHGYTFVPEIFAKDVLEAIAESAFKTSEYPVILSFENHCNPRQQAKIANYCREIFGDMLLDKPLDSHPLEPNMDLPPPAMLRRKIIIKNKKKHHHHHHHHHHKKPAQVGTPAANNKLTTANSVDAKAAQQVGLSASHEDGGVTRSTANGDVATGTGTGSAAGTAGHAPPLQQIRQSSKDSTGSSDSDSSSEDESLPNTTPNLPSGNEPPPEKAQKETEAGAEISALVNYVQPIHFSSFENAEKKNRCYEMSSFDEKQATTLLKERPIEFVNYNKHQLSRVYPAGTRFDSSNFMPQLFWNAGCQLVALNFQTLDLAMQLNLGIFEYNARSGYLLKPEFMRRSDRRLDPFAESTVDGIIAGTVSITVLSGQFLTDKRANTFVEVDMYGLPADTVRKKFRTKTVRDNGMNPLYDEEPFVFKKVVLPELASIRIAAYEEGGKLIGHRVLPVIGLCPGYRHVNLRSEVGQPIALASLFLCVVVKDYVPDDLSNFAEALANPIKYQSELEKRDIQLSVLTDEAEALGSADEDLSKSFVFVQVGGQKKELRPVESLATSPKHRPSISAAAAMSVDVTVDRTDGGRGEDSISIVAPSIQHQHSLDQSVSTSIRQVESSQFDVDLVLAEPLEKILDHKSVKEKRLEMEKKLESLRKKHDKEKIKIAGQKSSPLEGKKPKFAITNKLVKRLSNKSLNCLSPHSEPGVEIPACPLDLGDSSEESAAADAGEDLAGGSSSLDGRTQESRLRSACREYTSQYRELQEKYHEAIYSAAEKVLKTSQTGQTKQLKASLDKVTGEVMHQLQEARRNEVKNLATVHRDRDELIRMKREVASSVVERGVAERVRLKQTFDRRTDELQKQHDSVRNALAEHRSKARQILDKEAESRSCVSSNGFLVLFHGPHHHGCTGSGSSALSGNNLTLNLDAGAAGSHSAISPAKSHNSIAAAAEMKT
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase classes I and II, Phosphoinositide phospholipase C.
Protein: REMO_SOLTU
Sequence: MAELEAKKVEIVDPAPPAPGPVEAPKEVVADEKAIVAPALPPPAEEKEKPDDSKALVVVETKAPEPADEKKEGSIDRDAVLARVATEKRVSLIKAWEESEKSKAENKAQKKVSAIGAWENSKKANLEAELKKMEEQLEKKKAEYTEKMKNKIALLHKEAEEKRAMIEAKRGEDLLKAEELAAKYRATGTAPKKILGIF
What is the function of this protein?
Binds to both simple and complex galacturonides.  May be involved in cell-to-cell signaling and molecular transport.
What are the official names of this protein?
Remorin, pp34.
What is the protein family that this protein belongs to?
Belongs to the remorin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SPED_SHIFL
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: NU4LC_EUCGG
Sequence: MILEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDSRQLKGDIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNK
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COAD_PROM1
Sequence: MKALYPGSFDPLTFGHLDLIQRGSDLFGEVLIAVLENPSKKATFSCKRRIEQIENATKDIPGCRTIAFKGLTVDCARENNADLILRGLRAMSDFEYELQVAHTNRSLNNQYETIFLATETHHSFLSSSVVKEVARFGGEIRHMVPEFIAKDLMKLNTN
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRL2_HALMA
Sequence: MDRLKKSLLEAPIIEKEGYHYFVHPISDGVPMLRPELLREIVIKIIRKAELDDVDKIVTPAAMGIHISTAVSLMTDIPLVVVRKRQYGLDGEVSLSQVTGYSESEMYVNDVYEGDQVLVLDDVLSTGGTLAGLTGALEDIGADIRDIVCVIKKADGTNKLDEAGYDAKTLINVQVIDGEVTIVDEHGDD
What is the function of this protein?
May catalyze a purine salvage reaction, the substrate is unknown.
What are the official names of this protein?
HGPRTase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
Protein: YCCE_ECOLI
Sequence: MGSNIHGISCTANNYLKQAWNDIKNEYEKNQTYSITLFENTLVCFMRLYNELRRKVNEEDTPCLECESLEKEFEEMQNDNDLSLFMRILRTNDTQIYSGVSGGITYTIQYVRDIDIVRVSLPGRASESITDFKGYYWYNFMEYIENINACDDVFSEYCFDDENISVQPERINTPGISDLDSDIDLSGISFIQRETNQALGLKYAPVDGDGYCLLRAILVLKQHDYSWALVSYKMQKEVYNEFIKMVDKKTIEALVDTAFYNLREDVKTLFGVDLQSDNQIQGQSSLMSWSFLFFKKQFIDSCLNNEKCILHLPEFIFNDNKNLLALDTDTSDRIKAVKNFLVVLSDSICSLFIVNSNVASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKLNNKEMNAQLDYLNRYAI
What are the official names of this protein?
Uncharacterized protein YccE, ORF-D.
Protein: HEM3_ECO55
Sequence: MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQNAEQMGISLAEELLNNGAREILAEVYNGDAPA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YLM7_SCHPO
Sequence: MSSDDAIIIRCPFDCEFAGDSISFISHLTTIHNSSVQTLAKNAYLCASEIANELNQNPNLKDQEILLLQIAQENSLKRVLRQQQKERREGKIKSLQCLFCNNEGLLNRQEWFEHSFHVHGLNIGLADNIVYINRLLEKIKNELESFRCLCCHVPCKNKKLLREHMNNKRHFRLDPKSSEYDEFYIINYASVTKSITISHSQFAINEDINETDDTISDINDEDAEPLSVECIFCTNFYEPVFCFEHCKIVHDWDIKKIQKDYSLDVYGAIRVINYSRKTKKKSIPAETDSFWKEPGWLIPVVPDDALIICLSEVIEDPRL
What are the official names of this protein?
Zinc finger protein C19B12.07c.
What is the protein family that this protein belongs to?
Belongs to the ZNF277 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEPD7_RAT
Sequence: MATVREKAAALDLSALHSPAQRPPGFSVAQKPFGATYVWSSIINTLQTQVEVKKRRHHLKRHNDCFVGSEAVDVIYSHLTQNKFFGDVDIPRAKVVRVCQALMDYKVFEAVQTRVFGKDKKPAFEDSSCSLYRFTTIPNQDSQLGHENKGTSPSRFSDALFKSSDIKSDSLEDLWENLSLKPTNSPHVSTRLSPQVINEVWQEETIGRLLQLVDLPFLDSLLKQQEVVPKAPQSKRQPDMVNTSNYLDRGILRAYGDSQEDEWISAAIDCLEYLPDQMVVDISRNFPEQPDRTDLVKELLFGAIGKYYSTREPLLNHLSDVHNGIAELLVNGKTEIALEATQLFLKLLDSQNREEFRRLLYFMAVAADPSEFKLQEESDNRMVVKRVFSKAIVNNKNLSKGKTDLLVLFLMDHQKDVFKIPGTLHKIVSVKLLAIQKGRDPNKDTGYIYCQRIDGREYSSSIQKKTKDQLLSLLKTIDEDSKLSAKEKKKLLGQFHKSHPDIFIEYFGDSF
What are the official names of this protein?
DEP domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the DEPDC7 family.
Protein: IF1_UREPA
Sequence: MADTEKLKMLGKIVEVLQGGNFRVQLENGITIMSHVSGKMRVNKINILPGDTVDVELSPYDLTRGRITYRHRDN
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_ACIBY
Sequence: MAEFKFTDLVEPVAVDKKTALRITVLGGGSFGTAMANLAARNGCDTMIWIRDAETAEEINKTHINKRYLPDFTLESSLRAVSDLEQAVCDRDIILVAIPSHSFRDVLKQIAPYITAQAVVSLTKGVEAKTFSFMSDIIREELPEVPYGVLSGPNLAKEIMAGMPSGTVIASDSELVRYAVQHALHSALFRVFGSDDVHGVELGGALKNIYAVAMGIGAAYKIGENTKSMILTRALAEMSRFAVKQGANPLTFLGLSGVGDLFATCNSPLSRNYQIGYALGSGKTLEQASKELGQTAEGINTIVQVRGKAQELDVYMPITNALYEVIFEGAPPLNIALSLMKNGHRSDVEFVLPHHEV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_ALIF1
Sequence: MATVTAALVKELRERTGAGMMECKKALVEANADIELAIENMRKSGAAKAAKKAGNVAAEGAIIIKEENGVAALLEVNCQTDFVAKDSNFTAFAEEVVAAAVATQATVEELQAQFEETRVALVAKIGENINIRRVQYVAGSALASYRHGEKIGVVVAGEGDAETLKHIAMHVAASKPEYVNPSDVPADVVEKEKAVQVEIAMNEGKPQEIAEKMVIGRMKKFTGEVSLTGQAFIMEPKKTVAEILKEKGASVSNFVRLEVGEGIEKAAEMSFADEVAAVQKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4401_PECAS
Sequence: MSDIALTVSMLALVAVLGLWIGNWRIYGVGLGIGGVLFGGIIVGHVAHQYQIQLNDDMLHVIQEFGLILFVYTIGIQVGPGFFSSLRVSGLRLNAFALLTVFLGSVVTVMLHKLLNIPLPIILGIFSGAVTNTPSLGAGQQILTDLGSSTALVNQMGTGYAMAYPLGICGILLVMWLMRVLFRVAVDNEAKQFETSNGQHHEQLLTINVSVTNTNLQGLAIQDVPILNRDTIVCSRLKRGDELMVPSPHTLIQLGDYLHLVGAKNDLEQARLVIGNEVETSLSTRGTDLHVERVVVTNEKVLGRKIRELNLKQNYDVVISRLNRAGVELVASNQASLQFGDILNLVGRKTAIDAVADIVGNAQQKLQQVQMLPVFIGIGLGVLLGSVPLMVPGFPVALRLGLAGGPLVVALVLGRIGSIGKLHWFMPPSANLALRELGIVLFLSVVGLKSGGDFVDTLLNGDGVWWIGYGALITIVPLLAVGILARTLGKMNYLTLCGMLAGSMTDPPALAFANGLHPTSGAAALSYATVYPLAMFLRIMSPQLLAVLFLTL
What are the official names of this protein?
Putative transport protein ECA4401.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1809_SHESH
Sequence: MAIQSKYSNTQVESIIAEVSAVLDKHQAPTDLRLMVLGNCVTDLLARKVPQEARAAVAEQFSKALAQSVKG
What are the official names of this protein?
UPF0352 protein Ssed_1809.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: GRPE_BURP6
Sequence: MENTQENPTDQTTEETGREAQAAEPAAQAAENAAPAAEAALAEAQAKIAELQESFLRAKAETENVRRRAQDDVAKAHKFAIEGFAENLLPVLDSLEAAVGDTSGDLAKVREGVELTLRQLTSALEKGRVAALNPVGEKFDPHLHQAISMVPADQEPNTVVAVLQKGYTIADRVLRPALVTVAQPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.