PharMolix/UniProtQA huggingface dataset:
Protein: NGF_MOUSE
Sequence: MSMLFYTLITAFLIGVQAEPYTDSNVPEGDSVPEAHWTKLQHSLDTALRRARSAPTAPIAARVTGQTRNITVDPRLFKKRRLHSPRVLFSTQPPPTSSDTLDLDFQAHGTIPFNRTHRSKRSSTHPVFHMGEFSVCDSVSVWVGDKTTATDIKGKEVTVLAEVNINNSVFRQYFFETKCRASNPVESGCRGIDSKHWNSYCTTTHTFVKALTTDEKQAAWRFIRIDTACVCVLSRKATRRG
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems (PubMed:20036257).  Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (PubMed:22649032).  The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse (PubMed:22155786).  In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) (PubMed:20036257).  Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI (By similarity).  Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer (PubMed:22649032, PubMed:26144237).  The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form (PubMed:22649032).
What are the official names of this protein?
Beta-nerve growth factor, Beta-NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted. Endosome lumen. Note=ProNGF is endocytosed after binding to the cell surface receptor formed by SORT1 and NGFR.
Protein: FIE2_MAIZE
Sequence: MAKLGPGQGLGCEAAEGSLVPSRKREYKPCGKHTEGKRPLYAIGFNFMDARYYDVFATVGGNRVTTYRCLENGSFALLQAYVDEDKDESFYTLSWARDHVDGSPLLVAAGSNGIIRVINCATEKLAKSFVGHGDSINEIRTQPLKPSLIISASKDESVRLWNVHTGICILIFAGAGGHRNEVLSVDFHPSDIERFASCGMDNTVKIWSMKEFWLYVDKSYSWTDLPSKFPTKYVQFPVLIAAVHSNYVDCTRWLGDFILSKSVDNEIVLWEPKTKEQSPGEGSIDILQKYPVPECDIWFIKFSCDFHFNQLAIGNREGKIYVWEVQSSPPVLIARLYNQQCKSPIRQTAVSFDGSTILGAGEDGTIWRWDEVDHPSSRN
What is the function of this protein?
Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility (By similarity).
What are the official names of this protein?
Polycomb group protein FIE2, Protein FERTILIZATION-INDEPENDENT ENDOSPERM 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ESC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CIDB_STAAW
Sequence: MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGIIFVLLIFGISYNGYMKGGSWINHILNATVVCLAYPLYKNREKIKDNVSIIFASVLTGVMLNFMLVFLTLKAFGYSKDVIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIGSILGSMLLRFGRFESSIAKGLTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISSVLIPVLILLFY
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential (By similarity).
What are the official names of this protein?
Holin-like protein CidB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. CidB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH60_ECOL6
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3M_ANOGA
Sequence: MLMLSTMTLIIFIITIVVMMLATLLSKKTLLDREKCSPFECGFDPMNSSRLPFSLRFFLIAIIFLIFDVEIALLLPMIMIIKTSNLMNWTITSLFFIFILLIGLYHEWNQGALEWNE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: AQP5_BOTFB
Sequence: MSVTTLNGQPTLNISGPGQTALSRLDPLKKVFTKFFSSIPQKVRGHVVAVIGELIGTTAFLFIAFSAAEVALASANDNKGDKVSYETKSISTTQILFIAFGAGISLVVNAWTFFRISGGLFDPAVSIALFFVGAIDLTRCVLLCIAQCLGAIAASAMAYGLYHGGLHTATTLKPGMSPAQGVIVEMILTCQLCFTVLMLAAEKHEATFLAPLGIGLSVFIGELAGVFWTGGSMNPARSLGPAVVTLSFPSYHWIYWVGPIAGAGLASIIYKLIKALEYETAQLSEGEMHAHPVEDSEKASGHTGPCECMCFKVAAQGQSSAASTLQVATTDARKSSSLVPTKSTKSGNSEVKKTETVVEEPAKTQPKPAPAADDGFFGEMYAD
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes (Probable).  May play a role in the vegetative growth (PubMed:26527167).
What are the official names of this protein?
Aquaporin-5.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein: E2AK4_MOUSE
Sequence: MAGGRGASGRGRAEPQESYSQRQDHELQALEAIYGSDFQDLRPDARGRVREPPEINLVLYPQGLAGEEVYVQVELQVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSHLEELAKKQCGEVMIFELAHHVQSFLSEHNKPPPKSFHEEMLERQAQEKQQRLLEARRKEEQEQREILHEIQRRKEEIKEEKKRKEMAKQERLEITSLTNQDYASKRDPAGHRAAAILHGGSPDFVGNGKARTYSSGRSRRERQYSVCSGEPSPGSCDILHFSVGSPDQLMVHKGRCVGSDEQLGKVVYNALETATGSFVLLHEWVLQWQKMGPCLTSQEKEKIDKCKRQIQGAETEFSSLVKLSHPNIVRYFAMNSREEEDSIVIDILAEHVSGISLATHLSHSGPVPAHQLRKYTAQLLAGLDYLHSNSVVHKVLSASSVLVDAEGTVKITDYSISKRLADICKEDVFEQARVRFSDSALPYKTGKKGDVWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFINPQPKLPLVEQSPEDSGGQDYIETVIPSNQLPSAAFFSETQKQFSRYFIEFEELQLLGKGAFGAVIKVQNKLDGCCYAVKRIPINPASRHFRRIKGEVTLLSRLHHENIVRYYNAWIERHERPAVPGTPPPDCTPQAQDSPATCGKTSGDTEELGSVEAAAPPPILSSSVEWSTSAERSTSTRFPVTGQDSSSDEEDEDERDGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNQKDGSHEIEPSVTAEAVHYLYIQMEYCEKSTLRDTIDQGLFRDTSRLWRLFREILDGLAYIHEKGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFTAEGKQDDQAGDGVIKSDPSGHLTGMVGTALYVSPEVQGSTKSAYNQKVDLFSLGIIFFEMSYHPMVTASERIFVLNQLRDPTSPKFPDDFDDGEHTKQKSVISWLLNHDPAKRPTAMELLKSELLPPPQMEESELHEVLHHTLANIDGKAYRTMMSQIFCQHISPAIDYTYDSDILKGNFLIRTAKIQQLVCETIVRVFKRHGAVQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYCIERVFRPRKLDRFHPKELLECAFDIVTSTTNSSLPTAETIYTIYEIIQEFPALQERNYSIYLNHTMLLKAILLHCGIPEDKLSQVYVILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKFIEQKGDLQDLTPTINSLIKQKTGVAQLVKYSLKDLEDVVGLLKKLGVKLQVSINLGLVYKVQQHTGIIFQFLAFSKRRQRVVPEILAAGGRYDLLIPKFRGPQTVGPVPTAVGVSIAIDKIFAAVLNMEEPVTVSSCDLLVVSVGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQEYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLESDLVDHVMQKLRTKVGDERNFRDASDNLAVQTLKGSFSNASGLFEIHGTTVVPNVIVLAPEKLSASTRRRHEIQVQTRLQTTLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVCDEIYNIKVEKKVSVLFLYSYRDDYYRILF
What is the function of this protein?
(Microbial infection) Plays a role in modulating the adaptive immune response to Yellow fever virus infection; promotes dendritic cells to initiate autophagy and antigene presentation to both CD4(+) and CD8(+) T-cells under amino acid starvation.
What are the official names of this protein?
eIF-2-alpha kinase GCN2, Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein, mGCN2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_HTL32
Sequence: MPKTRKQRSRRPKNQRPSTPWPISQVSDRAFSTGTLSTFSATVYRPIGAPFLGGFVPLGYTAMPYWPRAPNIRLPGTPSMDALSAQLYNTLSLDSPPSPPRELPAPSRFSPPQPLLRPPRFLHPSSTPLKNTPPSETIALNSPWESSCQPCPSPTLGSDPKTSTPCGEAPLCAFTSISSPPP
What is the function of this protein?
Rex escorts unspliced gag-pro-pol and singly spliced env mRNAs out of the nucleus of infected cells.  These mRNAs carry a recognition sequence called Rex responsive element (RxRE or XRE) located at the 3' region of the long terminal repeat (LTR).  This function is essential since most HTLV proteins are translated from unspliced or partially spliced pre-mRNAs that cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rex, Rev homolog, Rex-3.
What is the protein family that this protein belongs to?
Belongs to the deltaretrovirus Rex protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import (NLS) and nuclear export (NES) signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: INT14_HUMAN
Sequence: MPTVVVMDVSLSMTRPVSIEGSEEYQRKHLAAHGLTMLFEHMATNYKLEFTALVVFSSLWELMVPFTRDYNTLQEALSNMDDYDKTCLESALVGVCNIVQQEWGGAIPCQVVLVTDGCLGIGRGSLRHSLATQNQRSESNRFPLPFPFPSKLYIMCMANLEELQSTDSLECLERLIDLNNGEGQIFTIDGPLCLKNVQSMFGKLIDLAYTPFHAVLKCGHLTADVQVFPRPEPFVVDEEIDPIPKVINTDLEIVGFIDIADISSPPVLSRHLVLPIALNKEGDEVGTGITDDNEDENSANQIAGKIPNFCVLLHGSLKVEGMVAIVQLGPEWHGMLYSQADSKKKSNLMMSLFEPGPEPLPWLGKMAQLGPISDAKENPYGEDDNKSPFPLQPKNKRSYAQNVTVWIKPSGLQTDVQKILRNARKLPEKTQTFYKELNRLRKAALAFGFLDLLKGVADMLERECTLLPETAHPDAAFQLTHAAQQLKLASTGTSEYAAYDQNITPLHTDFSGSSTERI
What is the function of this protein?
Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
What are the official names of this protein?
Integrator complex subunit 14, von Willebrand factor A domain-containing protein 9.
What is the protein family that this protein belongs to?
Belongs to the INTS14 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSRP_LEPIN
Sequence: MVKKKEESGHSPLVNKKAKFNFELISFIEAGIVLSGSEVKSLRDKKGNLTDAFAKIKNGEVFLENFSIAPYKNGGYANHPEIRPRKLLLHKKEIEKLERQVKEKGLVLVATKVYFKNNLRVKVEIAVGKPKKLHDKRDDLQKKDAQQEIARALKSSNRYQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MNHB1_STAA9
Sequence: MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B1, Mnh complex subunit B1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRMD_ANAMF
Sequence: MIFNVLTIFPDMFPGPLGYSTVGNALRKGLWSLNVVDIRSFASDKHSTVDDKPYGGGPGMLMKADVLGRCIDSVLEAHPDTRLVYTSPKGKQFTQDMSRQIVHFGNITLLCGRFEGIDERVVDVYNFQEVSIGDYVISGGELAAMVVIDSCVRMVTGVIGNKDSLTRESFDCGLEYPQYTRPASWKGVSVPDVLLRGNHKETELWRCKMSRIITERRRPDLLKDCGGEEEGSSNE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA_CUPTR
Sequence: MAQRITLHDMTLRDGMHPKRHQISLEQMKGIARGLDAAGVPLIEVTHGDGLGGASVNYGFPAHSDEEYLRAVLGELKQARVSALLLPGIGTVDHLRMAHEIGVQTIRVATHCTEADVSEQHIGMARKLGMDTVGFLMMAHMAPVQTLVQQALLMESYGANCLYITDSAGHMLPHDVTEKLTAVRQALRPETELGFHGHHNLAMGVANSLAAITCGATRIDAAAAGLGAGAGNTPMEVLVAVCERMGIETGVDVFRIADVAEDLVVPIMDHPIRIDRDALTLGYAGVYSSFLLFAKRAEAKYRIPAREILVELGRQRLVGGQEDMIEDTAITLARARGLPVA
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: THIM_STAAS
Sequence: MNYLNKIRIENPLTICYTNDVVKNFTANGLLSIGASPAMSEAPEEAEEFYKVAQGLLINIGTLTAENEQDIIAIAQTANEAGLPIVFDPVAVGASTYRKQFCKLLLKSAKVSVIKGNASEILALIDDTATMKGTDSDANLDAVTIAKKAYATYKTAIVITGKEDVIVQDNKAIVLANGSPLLARVTGAGCLLGGVIAGFLFRETEPDIEALIEAVSVFNIAAEVAAENENCGGPGTFSPLLLDTLYHLNETTYQQRIRIQEVEKYV
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: YWDI_BACSU
Sequence: MNIHISALIQKMEEELKKAKTAERDEELKRYVAVVRSLCDVVLDQPENASAPRIQPSVTPSPAAPPSTDQLMMEKMMGSAGLNKYRKQEKEKQEEDGNGESLFDF
What are the official names of this protein?
Uncharacterized protein YwdI.
Protein: Y679_VIBC3
Sequence: MNSVFEIVSLARRKNKLQRELDDNEKKVRDNRKRVELLVNLLDYIKPNMSHEEILGIIKNMKSDYEDRVDDHIIKSAEISKERRDISRRIKDLTEHDKQMTQGKKA
What are the official names of this protein?
UPF0265 protein VC0395_0679/VC395_A0572.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: CAPP_STRSV
Sequence: MSFNKLESYSNKEVIREEVAILTDLLADITRNLLSPETFEKISLMEDLAVNSKYHELKAIVEELTTDEMVYISRYFSILPLLINISEDVDLAYEINHQNNINQDYLGKLSTTIDLISTRENAQEILENLNVVPVLTAHPTQVQRKTILDLTNHIHSLLRQHRDVKAGLVNEKKWLGNLRRYIELMMQTDMIREKKLKVTNEITNVMEYYNSSFLQAITNFMVEYRRLAEERGIKLDNPKPITMGMWIGGDRDGNPFVTAETLKLSATLQSEVILNYYIDKVYTLYRTFSLSTNLSETSQAVAEMAALSTDKSVYRENEPYRRAFHYIQSKLIQTLLYLKEGNFSNDGQRLTDRAEEKLSAKANLSVSNKGREIIPNYIQSRISETLTELKKEETPSYKTAQEFKEDLQVIYDSLIEHHGEALVSGDLTELLQAVDVFGFFLASIDMRQDSSVHEACVAELLASANIVQDYSSLSEEEKCQVLLKQLLEDPRILSATHEPKSELLQKELEIFKTARQLKDAIGEEVIKQNIISHSTSVSDLLELAIMLKEVGLIDENGARVQIVPLFETIEDLDNSCNTMEKYLSLPIAQKWIASKDNYQEIMLGYSDSNKDGGYLSSCWTLYKAQQQLTAIGDKFGVKITFFHGRGGTVGRGGGPTYEAITSQPLRSINDRIRLTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMVTHKKSDSHTSDKYERIMDQVVNRSYQIYRDLVFGDERFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWSQSRVMFPGWYGVGSSFKEFIDEDPENNLAFLQFMYKRWPFFKSLLSNVDMVLSKSNMNIAFEYAQLCEDQNVRDIFNIILDEWQLTKDVILEIEGHDELLAENTYLRDSLHYRMPYFNVLNYIQLELIKRQRNGQLTPDQEKLIHITINGIATGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: DNAK_BACC4
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPKVIPNPEGNRTTPSVVAFKNEERQVGEVAKRQAITNPNTIMSVKRHMGTDYKVEVEGKDYTPQEISAIILQNLKASAEAYLGETVTKAVITVPAYFNDAERQATKDAGRIAGLEVERIINEPTAAALAYGLEKQDEEQKILVYDLGGGTFDVSILELADGTFEVISTAGDNRLGGDDFDQVIIDHLVAEFKKENNIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFISAGAAGPLHLELTLTRAKFEELSAGLVERTLEPTRRALKDAGFAPSELDKVILVGGSTRIPAVQEAIKRETGKEPYKGVNPDEVVALGAAVQGGVLTGDVEGVLLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMSADNKTLGRFQLTDLPPAPRGIPQIEVTFDIDANGIVNVRAKDLGTSKEQAITIQSSSGLSDEEVERMVQEAEANADADQKRKEEVELRNEADQLVFQTDKVVKDLEGKVDAAEVAKATEAKEALQAAIEKNELEEIRAKKDALQEIVQQLTVKLYEQAQAAAGQAEGAQGAQDAGAKKDNVVDAEFEEVKEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: EFTU_STRMU
Sequence: MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSAVNQPKDYSSIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKYLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDIPVIQGSALKALEGDTAQEDIIMELMHTVDDYIPDPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGTVKVNDEVEIVGIRDDIQKAVVTGVEMFRKQLDEGIAGDNVGVLLRGIQRDEIERGQVLAKPGSIHPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGIVSEIEA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_NITMU
Sequence: MSTLNIAVAGSSGRMGRALLEAVERAPDMRLSAALERSGSPYLGKDAGELIGSPCGIGITDNVDTALDGSQVLVDFTRPDGTLVHVDRCREKNIKMVIGTTGFSPRQKEALWIASRDIAIVLAPNMSVGVNVTLKLLETAARVLNEDYDIEIIEAHHRHKVDAPSGTALLMGEVVAKALGKELSEVAVYSREGHTGEREAGSIGFATVRGGDIVGDHTVMFAGTGERIEISHKASSRATFAEGALRAARFLADKRNGMFDMQDVLGLRQ
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIRA3_HUMAN
Sequence: MGNASFGSKEQKLLKRLRLLPALLILRAFKPHRKIRDYRVVVVGTAGVGKSTLLHKWASGNFRHEYLPTIENTYCQLLGCSHGVLSLHITDSKSGDGNRALQRHVIARGHAFVLVYSVTKKETLEELKAFYELICKIKGNNLHKFPIVLVGNKSDDTHREVALNDGATCAMEWNCAFMEISAKTDVNVQELFHMLLNYKKKPTTGLQEPEKKSQMPNTTEKLLDKCIIM
What are the official names of this protein?
GTP-binding protein Di-Ras3, Distinct subgroup of the Ras family member 3, Rho-related GTP-binding protein RhoI.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Di-Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RL30_BRUSI
Sequence: MAEKKGKTVTVEQIGSPIRRPAEQRATLIGLGLNKMHRRSTLEDTPAVRGMIAKLPHLVRVVDEA
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: CH60_BUCAP
Sequence: MGAKDVKFGNEARIKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPSITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATLLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVISAVEELKNLSVPCSDSKAITQVGTISANADEKVGALIAEAMEKVGNDGVITVEEGTGLQNELEVVKGMQFDRGYLSPYFINKPETGIVELENPYILMADKKISNVREMLPILESVAKSGKPLLIISEDLEGEALATLVVNSMRGIVKVAAVKAPGFGDRRKAMLQDISILTGGSVISEELAMDLEKSTLEDLGQAKRVVINKDTTTIIGGSGEKQAIQSRIGQIRQEIQEATSDYDKEKLNERLAKLSGGVAVLKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVAGKISNLRGHNEDQNVGIRVALRAMEAPLRQIVSNSGEEPSVVTNNVKDGKGNYGYNAATDEYGDMIDFGILDPTKVTRSALQYAASVAGLMITTECMVTDLPREDKSSDVASSPAGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSP2_STRPN
Sequence: MKNTVKLEQFVALKEKDLQKIKGGEMRISRIILDFLFLRKK
What is the function of this protein?
Acts as a pheromone, induces cells to develop competence for genetic transformation.
What are the official names of this protein?
Competence-stimulating peptide type 2, CSP-2.
What is the protein family that this protein belongs to?
Belongs to the ComC family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBT_MAIZE
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RF1_SALAR
Sequence: MKPSIVAKLEALHERHEEVQALLGDAGIIADQDRFRALSREYAQLSDVSRCFTDWQQVQDDIETAQMMLDDPEMREMAQEELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSMSEGEHGGYKEIIAKISGEGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPEAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAETAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDETMEGKLDMLIEPIVQEHQADLLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.