PharMolix/UniProtQA huggingface dataset:
Protein: C1GLT_HUMAN
Sequence: MASKSWLNFLTFLCGSAIGFLLCSQLFSILLGEKVDTQPNVLHNDPHARHSDDNGQNHLEGQMNFNADSSQHKDENTDIAENLYQKVRILCWVMTGPQNLEKKAKHVKATWAQRCNKVLFMSSEENKDFPAVGLKTKEGRDQLYWKTIKAFQYVHEHYLEDADWFLKADDDTYVILDNLRWLLSKYDPEEPIYFGRRFKPYVKQGYMSGGAGYVLSKEALKRFVDAFKTDKCTHSSSIEDLALGRCMEIMNVEAGDSRDTIGKETFHPFVPEHHLIKGYLPRTFWYWNYNYYPPVEGPGCCSDLAVSFHYVDSTTMYELEYLVYHLRPYGYLYRYQPTLPERILKEISQANKNEDTKVKLGNP
What is the function of this protein?
Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.  Plays a central role in many processes, such as angiogenesis, thrombopoiesis and kidney homeostasis development.
What are the official names of this protein?
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, B3Gal-T8, Core 1 O-glycan T-synthase, Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1, Beta-1,3-galactosyltransferase, Core 1 beta1,3-galactosyltransferase 1, C1GalT1, Core 1 beta3-Gal-T1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
Protein: BNIP3_HUMAN
Sequence: MSQNGAPGMQEESLQGSWVELHFSNNGNGGSVPASVSIYNGDMEKILLDAQHESGRSSSKSSHCDSPPRSQTPQDTNRASETDTHSIGEKNSSQSEEDDIERRKEVESILKKNSDWIWDWSSRPENIPPKEFLFKHPKRTATLSMRNTSVMKKGGIFSAEFLKVFLPSLLLSHLLAIGLGIYIGRRLTTSTSTF
What is the function of this protein?
Apoptosis-inducing protein that can overcome BCL2 suppression.  May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.  Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria.  The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix.  Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.
What are the official names of this protein?
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3.
What is the protein family that this protein belongs to?
Belongs to the NIP3 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein. Note=Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane.
Protein: SDC1_MESAU
Sequence: MRRAALWLWLCALALRLQPVLPQIVTVNVPPEDQDGSGDDSDNFSGSGTGALPDITLSRQASPTLKDVWLLTATPTAPEPTSRDAQATTTSILPAAEKPGEGEPVLTAEVDPGFTARDKESEVTTRPRETTQLLITHWVSTARATTAQAPVTSHPHRDVQPGLHETSAPTAPGQPDQQPPSGGTSVIKEVAEDGATNQLPTGEGSGEQDFTFETSGENTAVAAVEPDQRNQPPVDEGATGASQGLLDRKEVLGGVIAGGLVGLIFAVCLVGFMLYRMKKKDEGSYSLEEPKQANGGAYQKPTKQEEFYA
What is the function of this protein?
Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.  Regulates exosome biogenesis in concert with SDCBP and PDCD6IP.
What are the official names of this protein?
Syndecan-1, SYND1.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Secreted. Secreted, extracellular exosome. Note=Shedding of the ectodomain produces a soluble form.
Protein: GLGA_BACLD
Sequence: MKVLFAVSECVPFVKSGGLADVAGALPKELALLGIETVVMMPKYSLIAEDVRRRMVKTAECEVRVGWRRQFCGIEHLEHDGVSYYFLDHGYYFNRDSLYGHYDDGERFAFFSRAVLEALYALNFEADVIHTHDWHTGMVNYLLKEEYRKKPFYQHMKSVFTIHNLQFQGIFPKEAVHDLLGLDISHFTTEKLEFYGNINYMKGGIIAADQVTTVSPTYRDEILTPYYGERLEGVLSDKKDALTGILNGIDDVLYDPLNDPHIDYHYDAVNRDGKRKNKAVIQKTFGLPVNEDIPLISMVARLTKQKGFDLIKRVLHELFEEEDMQLIVLGTGEAEFENYFRYMEHAFPDRCKAYIGFHEPLSRKIYAASDLFLMPSKFEPCGLGQLIALRYGAVPVVRETGGLHDTVTAYRETTGEGNGFTFAHFNAHDMKHTIKRALSFYHRKEEWGRIVQKAMTHDVSWALSARQYQRLYSREIKGEAHVLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: GATA_CHLSY
Sequence: MTELHHLTVTAAQAALAAGDITAVELTEACLARINATEPTIRAFLHLTPDAALAAARAADERRQQGRSLGPLDGIPIAIKDVICTDGVPTTAGSRILAGFRPPYNATVIERLVAAGAVLVGKLNCDEFAMGSSTENSAYQITTNPWDPTRVPGGSSGGSAAAVAAGQVPATLGTDTGGSIRQPAALCGISGLKPTYGRVSRYGLIAYGSSLDQIGPMAWTVADLAVLLNVIAGHDPRDGTSAPIDTPDYTTALTGDIRGLRIGIPREYFVEGMEPGVESATRTAIEVLRDLGAILVDVSLPHTRYALPTYYIIAPAEASANLARFDGVRYGFRAEGETMWEQIEQTRGQGFGPEVRRRIMLGTYALSAGYYDAYYRRAQQVRTLIKRDFEQVFTQVDLLAAPTSPTVAFPIGQKINDPLAMYLSDVCTLPINLAGVPALVVPCGFSEGLPVGLQLIGRPFDEATLLRVGDAYQRLTEWHTQRPRLVV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MTNA_TOBAC
Sequence: MANGNEGDKTLLSICYNRGSLQLLDQRKLPLETIYLDIQDTKDGWDAIKEMVVRGAPAIAIAAALSLAVEVSNLSSFDGTSDDASDFLSNKLDYLVSSRPTAVNLSDAAVKLKEVIKKAATTAKDANSVFQAYIEAAEVMLEDDVTSNKAIGSYGASFLKEHLTDSQKITILTHCNTGSLATAGYGTALGVIRALYTDGVLERAFCTETRPFNQGSRLTAFELVHENIPATLIADSAAAALMNAGRVKAVIVGADRVAANGDTANKIGTYNLAVSAMHHGIPFYVAAPLTSIDLSLSSGQEIVIEERSPKELLHTRGGLGEQVAASGISVWNPAFDVTPANLISGIITEKGVITKKGAETFDIAEFVRKTSGNL
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TSE1_PSEAE
Sequence: MDSLDQCIVNACKNSWDKSYLAGTPNKDNCSGFVQSVAAELGVPMPRGNANAMVDGLEQSWTKLASGAEAAQKAAQGFLVIAGLKGRTYGHVAVVISGPLYRQKYPMCWCGSIAGAVGQSQGLKSVGQVWNRTDRDRLNYYVYSLASCSLPRAS
What is the function of this protein?
Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells.  Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987).  To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).
What are the official names of this protein?
Peptidoglycan amidase Tse1, Type VI secretion exported 1.
What are the subcellular locations of this protein?
Host membrane. Secreted. Note=Delivered to the target cell periplasm by the H1 type VI (H1-T6SS) secretion system.
Protein: RRAS_MOUSE
Sequence: MSSGAASGTGRGRPRGGGPGPRDPPPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDTAGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPIVLVGNKADLENQRQVLRSEASSFSASHHMTYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKDGGCPCVLL
What is the function of this protein?
Regulates the organization of the actin cytoskeleton.  With OSPBL3, modulates integrin beta-1 (ITGB1) activity.
What are the official names of this protein?
Ras-related protein R-Ras, p23.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Inner surface of plasma membrane possibly with attachment requiring acylation of the C- terminal cysteine (By similarity with RAS).
Protein: OASL1_RAT
Sequence: MAVAQELYSFPASKLDSFVAQWLQPTREWKEEVLETVQTVEQFLRQENFRGERGPAQDVRVLKVLKVGCFGNGTVLRSTTDVELVVFLSCFHSFQEEAKHHQAVLRLIQKRMSYCRDLLDLGLSNLSVIEEVPSSLIFTIQTRETWEPITVTIVPAFRALGPSCPNSAEVYVNLIKANGYPGNFSPSFSELQRSFVKHRPTKLKSLLRLVKHWYQQYVRDKCPRANLPPLYALELLTVYAWEAGTQEDSNFRLDEGLATVMELLQDHELLCIYWTKYYTLQHPVIERFVRRQLKGERPIILDPADPTHNVAQGYRWDIVAQRASQCLKQDCCYDDRDAPVPSWTVKRAPDIQVTVQQWGHPDLILWVNPYEPIKKLKEKIRLSRGYSGLQRLSFQEPGGQRQLIRSQCSLAYYGIFCDTQICLLDTISPEIQVFVKNPDGGSHAYAIHPLDFVLSLKQQIEDRQGLQSQEQQLEFQGRVLEDWFDFKSYGIQDSITIILSRKREGKAPSAPS
What is the function of this protein?
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA.  Displays antiviral activity via an alternative antiviral pathway independent of RNase L (By similarity).
What are the official names of this protein?
2'-5'-oligoadenylate synthase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the 2-5A synthase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm.
Protein: GPMA_STRGC
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDQAYTSVLKRAIKTTNLALEAADQLWVPVEKSWRLNERHYGGLTGKNKAEAAEQFGDEQVHIWRRSYDVLPPAMPHDDEYSAHTDRRYASLDDSVIPDAENLKVTLERALPFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKHLSDDEIMGVEIPNFPPLVFEFDEKLNVVKEYYLGK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: SVF1_CANAL
Sequence: MLKWVQSGLSAVAGTAEPEYGPDAIQPITKRIFDTNNGKIYRATEPKDFEWLSPNYTNVETQTFYFTDLSNGNIGFAQIIHSNVMGLTTTAQFTFRLYNVKDKSINLWTSTKLEDFEIKDSNFYAKDLSLELKDNKVYKLKSSVNKESIVEFEMERLTDGVIFGDDGMSFYGEDPEQPWGSMRHVFWPRCKVNGTITTADNKVIEINNGLTMFVMALQGMKPHHAAKSWNFMNFQSANHSAVQMEFTTPKSYGTTKVNIGIVTDNEKILIASIDNQVVHSDTKFDDVGGWDVPQKIEFNYIDGKDKDKQVASVSGNLSQLVERVDVMAEIPQFVKNIVSGVAGARPYIYQYANEFTIDINNGDGEKVKEDGVGFTEVTFISD
What is the function of this protein?
May be involved in the response to oxidative stress.
What are the official names of this protein?
Survival factor 1.
What is the protein family that this protein belongs to?
Belongs to the SVF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MSRA_XANOP
Sequence: MLGIGAFKQRIPRPGEALPGREQALPLHNTHLINGHPLRGEFTGLAQVQFGLGCFWGAERKFWKVPGVYTTAAGYAGGQTPNATYSEVCSGQTGHTEAVLVVFDEQAVSFEHLLRTFWESHDPTQGMQQGNDVGTQYRSAIYCTTQAQYAAALASRDAYQQQLTAAGYGAITTEIGFPAPTFYYAEDDHQQYLAKHPNGYCGLGGTGVSCPIGLDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: PNP_GLOC7
Sequence: MEEFDRSISFDGRDIRLKLGLLAPQAGGSVLIQSGDTAVLVTATKAASREGVDFLPLTVDYEERLYAAGRIPGGFLRREGRPPEKAILISRLIDRPLRPLFPHWLRDDIQVIATTLSMDEEVPPDVLAVTGASLAVILAEIPFFGPMAAVRVGLVGDDFIINPTYKEINTGDLDLVVAGSPDGVVMVEAGANQLPEQDIIEAIDFGYEAVRDLIAAQQDVMETLGVKLATLDPPPVNESVLEFIKTQTADEIKKVLSQYDLDKNGRDTALDEIKAAKVEEVIASLPEEDPIKVATTEEAKLVDTLFKDVTKKLMRSQIINEGVRVDGRQLDQVRPISCRVGLLPPRVHGSGLFCRGLTQVLSIATLGTPGDAQELADDLHPEDEKRYLHHYNFPPYSVGETRPMRSPGRREIGHGALAERAILPVLPTQQEFPYVVRVVSEVLSSNGSTSMGSVCGSTLALMDAGVPIIKPVSGAAMGLIKDGDEVRILTDIQGIEDFLGDMDFKVAGTDNGITALQMDMKITGLSMDIVAKAIEQARPARLHILDKMLSVIDSPRPELSPYAPRLLTMRIDPDMIGLVIGPGGKTVKSITEQTKTKIDIDDDGTVTISASEAEQAERAKQLIHNMTRKLNEGEVYVGRVTRIIQIGAFVEIMPGKEGMIHISQLAEGRVGKVEDELAVGDEVVVKVREIDNKGRLNLTRLGIHPDEAAAARKAAALL
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH_SUHVN
Sequence: MPASSVRLPLRLLTLAGLLALAGAAALARGAPQGGPPSPQGGPAPTAAPARGPTLFVLVGDGSARFVFQLGGLGALNDTRIRGHLLGRYLVSYQVVPPPVSAWYFVQRPRERPRLSGPPSGAELVAFDAPGVRRTYTTAAVWPAEVAVLADAEARCPAAVFNVTLGEAFLGLRVALRSFLPLEVIISAERMRMIAPPALGADLEPPGPPAGRFHVYTLGFLSDGAMHQTMRDVAAYVHESDDYLAQLSAAHAAALAAVVQPGPYYFYRAAVRLGVAAFVFSEAARRDRRASAPALLRVESDARLLSRLLMRAAGCPAGFAGLFDGRAERVPVAPADQLRAAWTFGEDPAPRLDLARATVAEAYRRSVRGKPFDQQALFFAVALLLRAGGPGDARETLLRTTAMCTAERAAAAAELTRAALSPTAAWNEPFSLLDVLSPCAVSLRRDLGGDATLANLGAAARLALAPAGAPGAAAATDGGAEEEEEDPVARAAPEIPAEALLALPLRGGASFVFTRRRPDCGPAYTLGGVDIANPLVLALVSNDSAACDYTDRMPESQHLPATDNPSVCVYCDCVFVRYSSAGTILETVLIESKDMEEQLMAGANSTIPSFNPTLHGGDVKALMLFPNGTVVDLLSFTSTRLAPVSPAYVVASVVGAAITVGILYALFKMLCSFSSEGYSRLINARS
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: RTCA_PYRHO
Sequence: MITIDGSYGEGGGQILRTSVALSTITGEPVRIVNIRANRPNPGLRPQHLHAILALKHLANAEVKGAHVGSRELVFIPKKLEAKEISIDIGTAGSITLVLQALLPAMVFAREKVKFRITGGTDVSWSPPVDYLSNVTLFALEKIGIHGEIRVIRRGHYPKGGGIVEGYVEPWNEKRELVAKEYSRIIKIEGISHATNLPSHVAERQARAAKDELLQLKVPIEIRTEISRSIGPGSGIVVWAETDCLRLGGDALGKKGKPAEIVGKEAAQELLDQLKPGHCVDKFLGDQLIPFLAFSGGVIWVSEITNHLKTNIWVVESFLGRIFDVDGNVGEPGKIRVIRRV
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRDC_BOVIN
Sequence: MSPARPCRGLRAVVAASMGLSEGPAGSARSGRLLRSPSPTPGARLLRLPGSGAGRAANPERGGWTEALRAAVAELRAGAVVAVPTDTLYGLACSASCSEALGAVYRVKGRSETKPLAVCLGRVADVYRYCHVRVPEGLLKDLLPGPVTLVMERSEELNKDLNPFTPLVGIRIPDHAFMQDLAQMFGGPLALTSANLSSQSSSLNVEEFQDLWPHLSLIIDGGPIGDGQSPECRLGSTVVDLSVPGKFGIIRPGCALESTSAILQEYGLLPSHGSCW
What is the function of this protein?
Cytoplasmic and mitochondrial threonylcarbamoyl-AMP synthase required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.  Participates in t(6)A37 formation in cytoplasmic and mitochondrial tRNAs (By similarity).  May regulate the activity of some transporters (By similarity).
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Cell membrane; Peripheral membrane protein. Note=A large fraction localizes in the cytoplasm, whereas a smaller fraction is imported to mitochondria.
Protein: RUVA_MYCLE
Sequence: MIFSVRGEVLEVALDHAVIEAAGIGYRVNATPSALATLRQGSQARLVTAMVVREDSMTLYGFSDAENRDLFLALLSVSGVGPRLAMATLAVHDAAALRQALADSDVASLTRVPGIGKRGAERIVLELRDKVGPVGASGLTVGTAADGNAVRGSVVEALVGLGFAAKQAEEATDQVLDGELGKDGAVATSSALRAALSLLGKTR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PTHP_BUCBP
Sequence: MFQRDIKITTPNGLHTRPAALLVKEAKKFISEINIISNGKSANAKSLFKLQTLGLVQNSLITISAHGIDEKVAVEDLAKFLTTLK
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I.  Phospho-HPr then transfers it to the PTS EIIA domain.
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_AERS4
Sequence: MKQYLQVTKPGIIFGNLISVIGGFLLASKGSLDVPLFILTMAGVSLVVASGCVFNNYIDRDIDCIMERTKNRALVRGLIAPGVSLWYASALGVAGIALLYWAANPLAALLAVLGFIVYVGVYSLYMKRHSVYGTLVGSLSGAAPPVIGYCAVSGQFDSGALILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGIVVAKHHITLYILAFMVPTLMLFLGGYAGYKYLIVATAVSVWWLGMALSGYKQAVDDSLWARKLFMFSIVTITCLSVMMSVDFQPDATPVLVSMLP
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PORB_ORYSJ
Sequence: MALQAATTTSFLPSALSARKEGAVKDSAFLGVRLGDGLKLETSALGLRTKRVSTSSVAIRAQASAAVSSPTVTPASPSGKQTLRKGTAVITGASSGLGLATAKALAETGRWHVVMGCRDFLKASRAAKAAGMEKGSYTIVHLDLASLDSVRQFVANVRRLEMPVDVVVCNAAVYQPTAKQPSFTADGFEMSVGVNHLGHFLLARELLADLTSSDYPSKRLIIVGSITGNTNTLAGNVPPKANLGDLRGLASGLDGVSSSAMIDGGEFDGAKAYKDSKVCNMLTMQEFHRRYHGETGVTFASLYPGCIATTGLFREHVPLFRLLFPPFQKYITKGYVSEEEAGKRLAQVVSDPSLTKSGVYWSWNNNSASFENQLSEEASDPEKAKKVWELSEKLVGLADHDQ
What is the function of this protein?
Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
What are the official names of this protein?
Protochlorophyllide reductase B, chloroplastic, PCR B, NADPH-protochlorophyllide oxidoreductase B, POR B.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DF139_ARATH
Sequence: MEPSNQIFFYLRRSKLLSGLGEIRMAKGQPLGTMERCYDMLTWGECVPDNCAFSCALKRHGKGGCIKAYDNRPACVCYYTCLRS
What are the official names of this protein?
Putative defensin-like protein 139, Putative low-molecular-weight cysteine-rich protein 7, Protein LCR7.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHCH2_HUMAN
Sequence: MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMATTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQFLECAQNQGDIKLCEGFNEVLKQCRLANGLA
What is the function of this protein?
Transcription factor.  Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen) (PubMed:23303788).
What are the official names of this protein?
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, Aging-associated gene 10 protein, HCV NS2 trans-regulated protein, NS2TP.
Protein: PPTC7_DANRE
Sequence: MLSVLSYGRLVARAVIGGLSQTDSRDYSLVSASFGFGKDFRKGILKKGMCYGDDACFIARHRSADVLGVADGVGGWRDYGVDPSQFSGTLMRTCERLVKEGRFVPSNPVGILTTSYYELLQNKVPLLGSSTACIVVLDRQSHRLHTANLGDSGFLVVRGGEVVHRSDEQQHYFNTPFQLSIAPPEAEGSVLSDSPDAADSSSFDVQLGDIILTATDGLFDNMPDYMILQELKKLKNTNYESTQQTAKSIAEQAHVLAYDPNYMSPFAQFACDNGLNVRGGKPDDITVLLSIVAEYTD
What is the function of this protein?
Protein phosphatase which positively regulates biosynthesis of the ubiquinone, coenzyme Q (By similarity).  Dephosphorylates the ubiquinone biosynthesis protein coq7 which is likely to lead to its activation (By similarity).
What are the official names of this protein?
Protein phosphatase PTC7 homolog.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GON1_MESAU
Sequence: QHWSYGLRPGGKRNAERLGDSFQEMDKEVDQLAEPQHLECTVHWPRSPLRDLRGVLESLIEEE
What is the function of this protein?
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
What are the official names of this protein?
Progonadoliberin-1, Progonadoliberin I.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: FIS_HAEIE
Sequence: MLEQQRNSADALTVSVLNAQSQVTSKPLRDSVKQALRNYLAQLDGQDVNDLYELVLAEVEHPMLDMIMQYTRGNQTRAANMLGINRGTLRKKLKKYGMG
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.