PharMolix/UniProtQA huggingface dataset:
Protein: PLSB_PSE14
Sequence: MTRSPFRRLVFGTLRRLLYLWVRSETINQSSFTLNLDRSRPVFYALQSPSISDLAVIDTECRKAGLPRPVLSVAVGNLIEPAAFFYLTPAPDWLGRQDKRGAPPTLERLVAAVSQNPGEDAQIIPVSVFWGQSPDRESSAWKLLFADSWAVTGRLRRLVSILILGRKTRVQFSAPIHMRELVGENKGYELTLRMTQRLLRVHFRNLKSAVIGPDVSHRRTVVKGLLDEPLVKQAIIEEAERENITQDKARDRALSYGNEIASDYTYSVIRFMEVVLSWFWNKIYDGIKVSHIEGVQEVAPGHEVIYVPCHRSHIDYLLLSYLLFCNGLTPPHIAAGINLNMPVVGSLLRRGGAFFMRRTFKGNPLYTAVFTEYLHTLFIKGFPVEYFVEGGRSRTGRMLQPKTGMLAITLRSFLRNSRMPIVFVPLYIGYERVLEGRTYLGELRGATKKKESIFDIFKVIGALKQRFGQVSVNFGAPIKLAEFLDGEQPDWREQALAPQFRPEWLSETTHRLGERVAQHLNEAAAVNPMNLVAVALLSTQRLALDDQAMERVLDLYLTLLRAVPYSPHTTLPEGDGRSLIEHVKGMDLLAEQKDALGKILYLNEQNAVLMTYYRNNVLHIFALPSLLASFFQSSSRMSREQILRYTRALYPFLQSELFIRWPLSELDEVVDQWLAAFVEQGLLRFKKDVYVRPEPSSREFVLLTLLSRAIAQTLQRFYMAIALLLNSGQNTLSAEQLEDLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLGVLRKDSAGKLSYHPMLGELAEGAAKRVLPAEIRLSIRQVALHSNEEEQDAGNGEGVA
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDHI_ESPTI
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKI
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HAP2_ARATH
Sequence: MVNAILMACILAGIFVGMFNEVDGIQILSKSKLEKCEKTSDSGNLNCSTKIVLNLAVPSGSSGGEASIVAEIVEVEDNSSSNMQTVRIPPVITVNKSAAYALYDLTYIRDVPYKPQEYHVTTRKCEHDAGPDIVQICERLRDEKGNVLEQTQPICCPCGPQRRMPSSCGDIFDKMIKGKANTAHCLRFPGDWFHVFGIGQRSLGFSVRVELKTGTRVSEVIIGPENRTATANDNFLKVNLIGDFGGYTSIPSFEDFYLVIPREAAEAGQPGSLGANYSMWMLLERVRFTLDGLECNKIGVGYEAFNTQPNFCSSPYWSCLHNQLWNFRESDINRIDRHQLPLYGLEGRFERINQHPNAGPHSFSIGVTETLNTNLMIELRADDIEYVFQRSPGKIINIAIPTFEALTQFGVAAVIIKNTGEVEASYSLTFDCSKGVAFVEEQFFIIKPKAVTTRSFKLYPTKDQAAKYICTAILKDSQFSEVDRAECQFSTTATVLDNGTQVTNPFQIPETQPKGFFDSIRILWTKIINGLVDFITGDTCRNKCSSFFDFSCHIQYVCLSWMVMFGLLLALFPITCLLLWLLHQKGLFDPCYDWWEDHFDLDHHRRLLPSRADVVNRHHHHHKHRHHHNHHRRTHQRHKHHHGQDDDVLQKMMLERDHSDSHYYHQLHRVHKDSKQKQRRRAKHGIVLPRDVHVERQRKQRLRES
What is the function of this protein?
Required for male fertility (PubMed:17079265, PubMed:20333238).  Plays a role in pollen tube guidance and successful gamete attachment (PubMed:17079265).  Essential for the fusion of gametes during double fertilization, where one male gamete fuses with the egg to produce a zygote, and another male gamete fuses with the central cell to produce the endosperm (PubMed:17079265, PubMed:20333238, PubMed:21209845).  Mediates the fusion of cell membranes (PubMed:28137780).  Not required for pollen tube outgrowth (PubMed:17079265, PubMed:20333238).
What are the official names of this protein?
Protein HAPLESS 2, GENERATIVE CELL SPECIFIC 1.
What is the protein family that this protein belongs to?
Belongs to the HAP2/GCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass type I membrane protein. Note=Predominantly localized in a perinuclear ring (PubMed:17079265). Redistribution to the cell membrane is mediated by EC1 peptides after their secretion upon sperm arrival (PubMed:23180860).
Protein: ATPF_HELPJ
Sequence: MFVVKMVLGFLILLSPLCATGLDISQTDIIERSLNFLLFVGILWYFLAKRLRSFLHSKSLEISKRLEEIQAQLKVSKEHKKKLLKELEQAKEKAELIISDANKEAYTITQKYELQTKMDVENLIKNSKALMDLEVKKIKRELVESVFKDLRESKKVSFNAQDCVNILKQRL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AAEA_ECOSM
Sequence: MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFTIDQPRYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
What is the function of this protein?
Forms an efflux pump with AaeB.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeA, pHBA efflux pump protein A.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: THIG_NITHX
Sequence: MLKFYDREFSSRLLIGTALYPSPKIMQDAIRAAGSQIVTVSLRRETAGGRTGDAFWSLIRELDVTVLPNTAGCKSVREAVTTAKLARELFGTSWIKLEVIADNDTLQPDVIGLVEAAAVLIKDGFKVFPYCTEDLGVAMRLVEVGCKVVMPWAAPIGSAKGIVNRDALRLLRERLPDITLVVDAGIGAPSHAAQACELGYDAVLLNTAVAKAADPVAMAGAFSLAVEAGRTAFEAGLMEARDFASPSTPVVGTPFWHAVS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_SOLUE
Sequence: MIALLRGLVVEKHPNQVLVETGGVGYDVTIPVSTFTKLPDLGGEVRLRIYTHVREDVLALYGFLTQDEKALFEKLISVSGIGPTLAVKILSGLAAADLILSIRRGEVEKLVKVPGVGKKTAERMVLELRDKLPAATGEEPGAPAAEALSPIDQDVLSALLNLGCARPQAEAAVRKAKAAGASLDFEPLFRRALELVR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CDSN_PANTR
Sequence: MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPMRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCRSIRDILAQVKPLGPQLADPEVFLPQGELLDSP
What is the function of this protein?
Important for the epidermal barrier integrity.
What are the official names of this protein?
Corneodesmosin, S protein.
What are the subcellular locations of this protein?
Secreted. Note=Found in corneodesmosomes, the intercellular structures that are involved in desquamation.
Protein: TRPB_BRASO
Sequence: MTTAIPNSYRSGPDERGHFGIFGGRFVAETLMPLILDLEKAYADAKADPAFQGEMNSYRTHYVGRPSPLYYAERLTEHLGGAKIYFKRDELNHTGSHKVNNVLGQIMLARRMGKKRIIAETGAGQHGVATATLCARFGLDCVVYMGAVDVERQQPNVLRMEMLGAKVIPVQSGARTLKDAMNEALRDWVTNVHNTFYCIGTVAGPHPYPMMVRDFQSVIGQETRTQMQEAEGRLPDSLVACIGGGSNAMGLFHPFLDDPSVEIFGVEAAGHGLTQLHAASIAGGRPGVLHGNRTYLLMDDDGQIAEAHSISAGLDYPGIGPEHSWLHEAKRVTYLSATDDEALDAFLLLSRLEGIIPALEPAHAVAKVMQLAPNKPKDHLMVVNLCGRGDKDVPQVGEILRKRAKQS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LDH_MESM1
Sequence: MDKKIKRVAMVGAGLVGVSVLYSCMNRGLAEQYGIIDINDKLSVGHSLDFEDASAANNHNFSVGKIEYSDLKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSIVVANPVDVMTFIYQHETGFDKNRVISSGTSLDSARLRFEISKKLKVHPKSVQAFVLGEHGDSSVSVYSAATVSGKSFNEIVKERGISKKELEDMHTTVYKKAYEIINRKGSTYFGIGSTVAELVEAILTDSHAIFGVGVYLTGQYGVKDLYIGVPTVLGSKGVVEVINFNLTKEEQEKFVSSATILKGNIQKALEAIKG
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
Protein: PSD_ECOBW
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYSA1_SHEON
Sequence: MSIRLTNISKKFGQFQALSPLNLDIQEGEMIGLLGPSGSGKTTLLRIIAGLEGADSGHIHFGNRDVTQVHVRDRRVGFVFQNYALFRHMTVADNVAFGLEVIPKKQRPSAAEIQKRVSHLLEMVQLGHLAQRYPEQLSGGQKQRIALARALATQPEVLLLDEPFGALDAKVRKELRRWLRSLHDELKFTSVFVTHDQDEALELSDRVVVMSNGNIEQVNTPIELYAQPNSRFVFDFLGNVNRFEANWQQNRWTNGDAFIVPPEQTPLQQNGALYVRSHELALADKPNSQAHIPFTIVAITPIGAEVRVELAPIGWQSEELWEAKFTHHHLQELGLQKGSVVYATPRTGYFFGKQGDGSPIRQSWPFLPPGSLAFDI
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA 1, Sulfate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEPA_BORAP
Sequence: MSISIRKKNFCIIAHIDHGKSTLADRFIQKAKIISDRDFKSQMLDSMEIERERGITIKSQAVTITYKSNDGDFYELNFVDTPGHVDFSYEVSRAISSCEGALLLIDASQGIQAQTVSNFYMAFEHDLEIIPVINKIDLPNANVDFIKKQIKNDLGLNDELAISISAKNGIGIDDLLEAICKYVPSPKGSIKDPLRALIFDSHYDSYRGVVVHFRIFEGQIKTGDKIRLMHTNSDYLIEEIGVFKILLERKDRLEAGDVGYFIAGIKNISDVKIGDTVTLCDCPALSPLEGFKEVKPVVFSSVYPVDANQYDDLLRAMDRLKLNDASLTFEKDSSSALGHGFKCGFLGLLHLEVIQERIEREFDLNVILTSPSVRYKIIPKKGKSYFIESPEQFPGNEAIESVLEPYIRANIIVPTEFLGNIMSVCLLKRGVQTNLIYLNTKRVELIYKMPLAEILFDFYDKIKSVSRGYASFDYELLDYEYTDLVRLDILVNGDRVDALSQLVFKDSARTKAVGICKKLKDEIARQQFKIAIQGAIGSNVIARETISPVRKDVTAKCYGGDITRKRKLLEKQKEGKKRMKMVGNVEIPQSVFLSVLKSNDN
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MNME_NOVAD
Sequence: MTDTIFALSSGQPPAGIGVIRISGPGAGAALSSLAGRLPSPRRATLATLADPRDGTHLDRTMVLWLPGPATATGEDCAELHLHGGRAVIAAVEAALSSLPGLRRARPGEFTRRAFANGRIDLAEAEGLADLLSAETELQRRTALAMAEGALSREVDEWRTTLLQISARLEAALDFSDEDDVGAGDGTQRASLLPPHFAADCISLACSLNTWLDRPRAEPLKEGFRVVLAGPPNAGKSTLFNALVEHEAAITAAEPGTTRDLLTHAAALDGVPFTFVDTAGLRDEGAGEIERIGIARARAAAEKADLILWLGPEGLGPAGRTLWEIAARADDPGAGRKSQCAFHLSAVTGEGMAAFRSALIAHARSALPAPGEAALNQRQHTHLSEVARALEDAAAEQDPLLAAENLRLGRRGLDALVGRTGTEDMLDTLFGRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRGB_STAA2
Sequence: MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
What is the function of this protein?
Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and/or CidB.  The LrgAB and CidAB proteins may affect the proton motive force of the membrane.  May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses.
What are the official names of this protein?
Antiholin-like protein LrgB.
What is the protein family that this protein belongs to?
Belongs to the CidB/LrgB family. LrgB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H2O01_CYRHA
Sequence: MKVTLIAILTCAAVLVLHTTAAEELEAESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEDNKDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1g, U4-TRTX-Hhn1g, Hainantoxin-II-15, HNTX-II-15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_FRAP2
Sequence: MAHKKAGGSTRNGRDSNPKYLGVKRYGGEFVKAGTIILRQRGTKTHPGVNVGCGKDHTLFALKDGTVKFHVGGALNRKFVSIDE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: EIF3B_YEAS7
Sequence: MKNFLPRTLKNIYELYFNNISVHSIVSRNTQLKRSKIIQMTTETFEDIKLEDIPVDDIDFSDLEEQYKVTEEFNFDQYIVVNGAPVIPSAKVPVLKKALTSLFSKAGKVVNMEFPIDEATGKTKGFLFVECGSMNDAKKIIKSFHGKRLDLKHRLFLYTMKDVERYNSDDFDTEFREPDMPTFVPSSSLKSWLMDDKVRDQFVLQDDVKTSVFWNSMFNEEDSLVESRENWSTNYVRFSPKGTYLFSYHQQGVTAWGGPNFDRLRRFYHPDVRNSSVSPNEKYLVTFSTEPIIVEEDNEFSPFTKKNEGHQLCIWDIASGLLMATFPVIKSPYLKWPLVRWSYNDKYCARMVGDSLIVHDATKNFMPLEAKALKPSGIRDFSFAPEGVKLQPFRNGDEPSVLLAYWTPETNNSACTATIAEVPRGRVLKTVNLVQVSNVTLHWQNQAEFLCFNVERHTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAIPANTIRFYAPETKEKTAKDVIKRWSLVKEIPKTFANTVSWSPAGRFVVVGALVGPNMRRSDLQFYDMDYPGEKNINDNNDVSASLKDVAHPTYSAATNITWDPSGRYVTAWSSSLKHKVEHGYKIFNIAGNLVKEDIIAGFKNFAWRPRPASILSNAERKKVRKNLREWSAQFEEQDAMEADTAMRDLILHQRELLKQWTEYREKIGQEMEKSMNFKIFDVQPEDASDDFTTIEEIVEEVLEETKEKVE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 90 kDa subunit homolog, eIF3 p90, Translation initiation factor eIF3, p90 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_LEGPL
Sequence: MTVRTRFAPSPTGFLHVGGVRTALFSWLYAKHHNGQFILRIEDTDRERSTQESVQAILDGMAWLGLNFDEGPYYQTERYARYQQVAQQLLEEGKAYRCQCSKERLEALREAQLAAKEKPRYDGHCRNQSLPDSGIPYVIRFRNPDGGIVSFHDEVYGDIHVDNSELDDLILVRSDGHPTYNFAVVIDDWDMKITHVIRGDDHINNTPRQINLFKALDAPVPVFAHLPMILGEDGKRLSKRHGAVSVLQFKELGVLPHALLNYLVRLGWSHGDQEIFSVQEMITSFDLKNVSRGVSSFNYDKLYWLNQHYQKSDSPESVANALQWHFEQAGIDLNQGPDLKDLVAVQAERCKSLAEMCQISQYFYTDTIEYNEDAVKKHLRPVVLEPLMVLHERLKALDEWKNDKIQECINDVSLQFDLNLGKIAQPLRVAVTGSGTSPSIDMTLALLGKNKSIKRLEDALEKIRARASVV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VANTE_ENTFL
Sequence: MKHRANGIDLFRIFAATMVVAIHTFPFQSIAPFLDEVITLTVFRVAVPFFFMITGYFLLGRLSLNFSYNNNQRVKKYLYKIGMIYLYSILLYFPLSLLNGTISLKMNILLLLKVFIFDGTFYHLWYFPASIIGTILVTLLLRSIGFKLTVAFSTCLYLVGLGGDSWYGITNQVPLLNKLYTFIFSWSDYTRSGVFFTPVFLCLGIFAYRVSKKLTASKILNLLFYVFIIGMTFESIFLHRFTNVKHDSMYLLLPSCALILFLMLLNWQPKLKVKESADLTLLVYILHPLVIVIVHSISKYIPILKNSLLNFLLVVVCSFILAQLLLNLKRKLRVSKQKIPFERASKEISASAIHHNINEIRKIIPKNTNIMGVVKANAYGCGMVEVAYELEKIGISFFCVATIEEAIALRKSGNQGDILILGYTHPNRINDIKKYNLIQSIVSEEHGKVLNLKKIPIRCHLQVDTGMHRLGVTPNVTIIQQMYLFSNLKIEGIYSHLGSSDSLEQESIARTNTQIFLFNNILSDLEQMGISYGYTHIQSSYGILNYPELSFDFVRIGILCYGFLSDYNSPTKIPIDLQPIVKVKASLITERIVEAGEYVGYGLGAKVEKRTRIGVVSIGYADGIPRALSNAKLTLEFKGQSIKQIGNICMDMMLVDLSEVEDISLNDELIVLPNISKIADEEQTITNELLSRLGSRLGTELN
What are the official names of this protein?
Amino-acid racemase, Vancomycin E-type resistance protein VanT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the alanine racemase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TGT_ACIF5
Sequence: MSIFQLLARDGAARRGTIRLPRGTVQTPAFMPVGTYGTVKAMSPEELKTLGAEIILGNTFHLFLRPGLEVISAVGGLHRMMHWDRPILTDSGGFQVFSLGALRKLTEAGVQFRAPTDGHMVFLGPEESMQIQAALGSDIAMVFDECTPHPASYEEARVSMELSLRWAARSHAAYAGPGELFGIVQGGMYADLRRRSLAGLQRLDFPGLAIGGLSVGESKVEMMQVLDDLMPHMPADRPRYLMGVGTPEDLVEGVRRGVDMFDCVMPTRNARNGWLFTRDGVLKLRNARYEKDVLPPDPACACYTCQNYSRAYLRHLQRSHEILGARLNTLHNLHYYQELMAGLREAIAAGRLDAYADDFYRRRRAGSLVGA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: FLIW_GEOUR
Sequence: MKVTTTRFGELDIEEGKVIHMPEGMLGFVEKRFILLTPENLGPFCWLQAVDNPDLAFVVADAKNCAPGYTFALTAEECRALELSERSEAIFLLVVTMAPEPGDITVNLRGPIVLNPERLIARQIVIEGEKYTTRHPFFETSEKKQSGLQRLERQPEKSVPPAG
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP19_CALMQ
Sequence: MGKKDYWVVWRINIDSTVSRSNGRVVPRQLAVDKPTLEEIAKAASMLGLKYEAHPEKKHPRHWFEEDYVGCIYVYKVDDYSRRSLIKKLAQIVKSSRRGG
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_OPITP
Sequence: MLNASPLQTLDPQVFSAISEELARQQSHIELIASENFTYPAVMEAQGSVLTNKYAEGYPAKRWYGGCEFVDKVEVLAIERAKKLFGAEHANVQPHSGAQANTAVYAAVLQPGDKVLGMNLSHGGHLTHGNPANFSGKLYQFCQYGVREDNGLIDYDELAATADREKPKMITVGASAYSRIIDFARMGEIARGVGAYLFADIAHIAGLVAAGAHPSPVPHADFVSTTTHKTLRGPRGGLVLCKAAHAKALDSAVFPGTQGGPLMHIIAAKAVCFGECLKPEFKAYSEQIVKNSKALAAAFLSRGYKIVSGGTDNHLFLVDLRTKYPELTAKKAQETLDLANITCNKNTVPFETRSPFQASGIRLGTPAVTTRGFREAHMADIADCIDSVLAAIGTEREAVVVAATKKRVTTLTSRFPLPYQL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_STRSY
Sequence: MKLNKYIDHTILKPETTQEQVEKILAEAKEYDFASVCVNPTWVALAAESLKDSDVKVCTVIGFPLGANTPAVKAFETKDAISNGADEIDVVINIGALKTGNYDLVLEDIKAVVAASGDKLVKVIIEACLLTDDEKVKGCQLSQEAGADYVKTSTGFSTGGATVADVALMRKTVGPDMGVKASGGARSYEDAIAFIEAGASRIGASSGVAIMNGAQADGDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB1C_DICDI
Sequence: MGCSPSKEGNGSFSSTSTSFIHGSESHPEYDMLLKILVIGDSGVGKSCMLLRFADNRFTDSYISTIGVDFCIRTIELDGKKIKLQIWDTAGQERFKTITTSYYRGAHGLIIVYDITSMDSFNSIKRWLIDVDRFASPSVLKLIVGNKCDLNSKRAVDFKIAKKFADELNIPIMETSAKESTAIDEAFIKLASDIKKSTPQK
What are the official names of this protein?
Ras-related protein Rab-1C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.