PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_BALPH
Sequence: MNENLFAPFMIPVMLGIPITTLIIILPSMLFPAPNRLINNRTIAIQQWLTKLTSKQLMNVHSPKGQTWSLMLISLFLFIASTNLLGMLPHSFTPTTQLSMNVGMAIPLWAGTVTTGFRNKTKMSLAHLLPQGTPTFLIPMLVIIETISLFIQPVAWAVRLTANITAGHLLMHLIGETTLALMNINLFSAFITFTILALLTILEFAVALIQAYVFTLLVSLYLHDNT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, F-ATPase protein 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RECO_STRA3
Sequence: MRVSQTYGLVLYNRNYREDDKLVKIFTETEGKRMFFVKHASKSKFNAVLQPLTIAHFILKINDNGLSYIDDYKEVLAFQETNSDLFKLSYASYITSLADVAISDNVADAQLFIFLKKTLELIEDGLDYEILTNIFEVQLLERFGVALNFHDCVFCHRVGLPFDFSHKYSGLLCPNHYYKDERRNHLDPNMLYLINRFQSIQFDDLQTISVKPEMKLKIRQFLDMIYDEYVGIHLKSKKFIDDLSSWGSIMKSD
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: GUC2B_MOUSE
Sequence: MSRSQLWAAVVLLLLLQSAQGVYIKYHGFQVQLESVKKLNELEEKEMSNPQPRRSGLLPAVCHNPALPLDLQPVCASQEAASTFKALRTIATDECELCINVACTGC
What is the function of this protein?
Endogenous activator of intestinal guanylate cyclase.  It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.  May be a potent physiological regulator of intestinal fluid and electrolyte transport.  May be an autocrine/paracrine regulator of intestinal salt and water transport (By similarity).
What are the official names of this protein?
Guanylate cyclase activator 2B.
What is the protein family that this protein belongs to?
Belongs to the guanylin family.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PI_PLAFA
Sequence: MNMEITNLKSYKELVTLSAEEKTKDLKDYLNDKNRSESLIKKFKNFYMDLSRQRYSEKTLNKLVEYAEEVELKKKVEKTFMGEKVNMTENRSVLHTALRIPIEKINTHKIIIDNKNVLEDVHGVLKKIEKYSDDIRNGVIKTCKNTKFKNVICIGIGGSYLGTEFVYEAMKYYYYNMELNKNEKDQVNNFNNNYDQDNVFNVRFLANVDPNDVNRAIQNLDQYDTLVIIISKTFTTAETMLNARSIKKWLSLKIKDDENLSKHMVAVSTNLKLTDEFGISRDNVFEFWDWVGGRFSVTSSVGILPLSIAFGYKNMRNFLNGCHDMDEHFLHADLKENIPVLLALTSFYNSHFFDYKNVAILPYFQNLLKFSAHIQQLSMESNGKSVDRNNQPIHYNTCQVYFGEPGTNGQHSFYQLIHQGQVIPVELIGFKHSHFPIKFDKEVVSNHDELMTNFFAQADALAIGKTYEQVKEENEKNKMSPELLTHKVFNGNRPSTLLLFDELNFYTCGLLLSLYESRIVAEGFLLNINSFDQWGVELGKVLAKEVRNYFNDTRNQKKSDNTYNFNESTKNFIKLLLVQIKKKKKINTNLK
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_NEIMF
Sequence: MTAQTLYDKLWNSHVVREEEDGTVLLYIDRHLVHEVTSPQAFEGLKMAGRKLWRIDSVVSTADHNTPTGDWDKGIQDPISKLQVDTLDKNIKEFGALAYFPFMDKGQGIVHVMGPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHTMATQCITAKKSKSMLIAVDGKLKAGVTAKDVALYIIGQIGTAGGTGYAVEFGGEAIRSLSMEGRMTLCNMAIEAGARSGMVAVDQTTIDYVKDKPFAPEGEAWDKAVEYWRTLVSDEGAVFDKEYRFNAEDIEPQVTWGTSPEMVLDISSKVPNPAEETDPVKRSGMERALEYMGLEAGTPLNEIPVDIVFIGSCTNSRIEDLREAAAIAKDRKKAANVQRVLIVPGSGLVKEQAEKEGLDKIFIEAGFEWREPGCSMCLAMNADRLTPGQRCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAVTGRFTDIRMMA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SOBRL_ARATH
Sequence: MRTSRLKKPIVLLTIALLSSVFFFAFFFLNKSDVSSTSALRNRDSMARTFILWLHGLGDSGPANEPIKTLFRSQEFRNTKWLFPSAPPNPVSCNYGAVMPSWFDIPELPLTAGSPKDESSLLKAVKNVHAIIDKEIAGGINPENVYICGFSQGGALTLASVLLYPKTIGGGAVFSGWIPFNSSITNQFTEDAKKTPILWSHGIDDKTVLFEAGQAALPFLQQAGVTCEFKAYPGLGHSISNEELQYLESWLKQRMQSSSSSS
What is the function of this protein?
Carboxylesterase.
What are the official names of this protein?
Probable carboxylesterase SOBER1-like.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
Protein: SFSA_YERP3
Sequence: MPANAPLLQFTPPLQPATLILRYKRFLADIVTPAGEALTIHCANTGAMTGCATPGDTIWYSTSDNPKRKYPQSWELTQTQTGDWICVNTMRANELVNLAIEKNQIAELSGYNFVRKEVKYGEENSRIDLLLQAEDRRDCYIEVKSVTLLQQQCGYFPDAVTLRGQKHLRELQNRVVNGHRAVLFFAVLHTGIKQVAPARHIDRRYAELLVQAQQAGVEVICYGFQLSPDGIALNTRLPLLLDEMLSSENAE
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: DEXHC_ARATH
Sequence: MANLGGGAEAHARFKQYEYRANSSLVLTTDNRPRDTHEPTGEPETLWGKIDPRSFGDRVAKGRPQELEDKLKKSKKKERDVVDDMVNIRQSKRRRLREESVLTDTDDAVYQPKTKETRAAYEAMLGLIQKQLGGQPPSIVSGAADEILAVLKNDAFRNPEKKMEIEKLLNKIENHEFDQLVSIGKLITDFQEGGDSGGGRANDDEGLDDDLGVAVEFEENEEDDEESDPDMVEEDDDEEDDEPTRTGGMQVDAGINDEDAGDANEGTNLNVQDIDAYWLQRKISQAYEQQIDPQQCQVLAEELLKILAEGDDRVVEDKLLMHLQYEKFSLVKFLLRNRLKVVWCTRLARAEDQEERNRIEEEMRGLGPELTAIVEQLHATRATAKEREENLQKSINEEARRLKDETGGDGGRGRRDVADRDSESGWVKGQRQMLDLESLAFDQGGLLMANKKCDLPPGSYRSHGKGYDEVHVPWVSKKVDRNEKLVKITEMPDWAQPAFKGMQQLNRVQSKVYDTALFKAENILLCAPTGAGKTNVAMLTILQQLEMNRNTDGTYNHGDYKIVYVAPMKALVAEVVGNLSNRLKDYGVIVRELSGDQSLTGREIEETQIIVTTPEKWDIITRKSGDRTYTQLVRLLIIDEIHLLHDNRGPVLESIVARTLRQIETTKENIRLVGLSATLPNYEDVALFLRVDLKKGLFKFDRSYRPVPLHQQYIGISVKKPLQRFQLMNDLCYQKVLAGAGKHQVLIFVHSRKETSKTARAIRDTAMANDTLSRFLKEDSVTRDVLHSHEDIVKNSDLKDILPYGFAIHHAGLSRGDREIVETLFSQGHVQVLVSTATLAWGVNLPAHTVIIKGTQVYNPEKGAWMELSPLDVMQMLGRAGRPQYDQHGEGIIITGYSELQYYLSLMNEQLPIESQFISKLADQLNAEIVLGTVQNAREACHWLGYTYLYIRMVRNPTLYGLAPDALAKDVVLEERRADLIHSAATILDKNNLVKYDRKSGYFQVTDLGRIASYYYITHGTIATYNEHLKPTMGDIDLYRLFSLSDEFKYVTVRQDEKMELAKLLDRVPIPIKETLEEPSAKINVLLQAYISQLKLEGLSLTSDMVYITQSAGRLVRALYEIVLKRGWAQLAEKALNLSKMVGKRMWSVQTPLRQFHGLSNDILMQLEKKDLVWERYYDLSAQELGELIRSPKMGKPLHKFIHQFPKVTLSAHVQPITRTVLNVELTVTPDFLWDEKIHKYVEPFWIIVEDNDGEKILHHEYFLLKKQYIDEDHTLHFTVPIFEPLPPQYFVRVVSDKWLGSETVLPVSFRHLILPEKYPPPTELLDLQPLPVTALRNPNYEILYQDFKHFNPVQTQVFTVLYNTNDNVLVAAPTGSGKTICAEFAILRNHHEGPDATMRVVYIAPLEAIAKEQFRIWEGKFGKGLGLRVVELTGETALDLKLLEKGQIIISTPEKWDALSRRWKQRKYVQQVSLFIVDELHLIGGQHGPVLEVIVSRMRYISSQVINKIRIVALSTSLANAKDLGEWIGASSHGLFNFPPGVRPVPLEIHIQGVDISSFEARMQAMTKPTYTAIVQHAKNKKPAIVFVPTRKHVRLTAVDLMAYSHMDNPQSPDFLLGKLEELDPFVEQIREETLKETLCHGIGYLHEGLSSLDQEIVTQLFEAGRIQVCVMSSSLCWGTPLTAHLVVVMGTQYYDGRENSHSDYPVPDLLQMMGRASRPLLDNAGKCVIFCHAPRKEYYKKFLYEAFPVESQLQHFLHDNFNAEVVAGVIENKQDAVDYLTWTFMYRRLPQNPNYYNLQGVSHRHLSDHLSELVENTLSDLEASKCIEVEDEMELSPLNLGMIASYYYISYTTIERFSSLLSSKTKMKGLLEILTSASEYDMIPIRPGEEDTVRRLINHQRFSFENPKCTDPHVKANALLQAHFSRQNIGGNLAMDQRDVLLSATRLLQAMVDVISSNGWLNLALLAMEVSQMVTQGMWERDSMLLQLPHFTKDLAKRCQENPGKNIETVFDLVEMEDEERQELLKMSDAQLLDIARFCNRFPNIDLTYEIVGSEEVNPGKEVTLQVMLERDMEGRTEVGPVDSLRYPKTKEEGWWLVVGDTKTNQLLAIKRVSLQRKVKVKLDFTAPSEPGEKSYTLYFMCDSYLGCDQEYSFSVDVKGSGAGDRMEE
What is the function of this protein?
RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes.  Involved in spliceosome assembly, activation and disassembly.
What are the official names of this protein?
DExH-box ATP-dependent RNA helicase DExH12, BRR2 homolog A, AtBRR2A, Pre-mRNA-splicing helicase BRR2A, Protein EMBRYO DEFECTIVE 1507.
What is the protein family that this protein belongs to?
Belongs to the DExH box helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPN2_ASHGO
Sequence: MSVITAAPLLALLREDDHTVKSYALHSINEVVDQLWSEVSNDITDIEALYEDSKFEDRKLAALVVSKIYYNLGEYESAVRYALAAEEYFDINEKSRYVETIVSQSIEMYIKLATENYGKEKSEIDLQLVSIFERMLNKCITAGEYKLALGIALESYRLDVVTNILTQQTSEPNMLKLITYVLIAATTTVSNTHFKINILYALFDILIRLKAPDYFAVSKIIVNLNDSKLAARLFDKLVSEKNTEIAYQIAFDLVTSASQGLLNELVATLSTGEGNDRLVEILSGLPTCDFYNTFLHANKRIDRSLLNKSKSSMDGKFSLFHTAVSVSNAFMHAGTTDDTFVRANLQWLGKAQNWAKFTATASLGIIHQGNLTGGKKIMEPYLPGSRASSRYIKGGSLYGLGLIYAGYGKEIIGYLKDQIVENSSNATDDDVDVLLHGASLGIGLAGMSSNSTEIFEALKEVLYADSANSGAAAALGIGLTMLGSGDETVAENLYTYAQETSHGEITKGLAIALALLNYGREELADETIKKMLEHENDSMRYGAVYTIALAYAGTSSNEAVKKLLHVAVSDSNDDVRRASVTALGFVLIRDYTTVPRIVELLSESHNPHVRCGTAFALGVACAGRGLQAAIDVLEPLTNDPVDFVRQAAMIALSMILIQQTEKTNVKVRDVNEQLRNVIANKHQEGLAKFGACVAQGIINAGGRNVTIQLENSEMGTLNTKSVIGLAMFTQFWYWFPLAHFLSLSFTPTTTIGVRSHDLKIPKFSFHCHTKEGIFDYPPMFEEDIDKSIEKVATAVLSTTAKAKARAKKSKKDKAVEPDKSKEEIKVENEQRDKKEHDADVPEEEFKIKYTSTYYKVENMTRVVPQQLKYIAFPKDERFTPVRKFKGSNGVIVLSDKTPDEPVEVIKTVRQEKETDAPLPAPFKVQDDLEF
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
What are the official names of this protein?
26S proteasome regulatory subunit RPN2.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S1 family.
Protein: GRM2A_MOUSE
Sequence: MQMKMMFFCLSDWQSNQQMHGKMAPLKSHVPCTEKPGKVQEPPDDGSLHWSEGSKGEDIKKYSREGTLRSKYNQQYHKLFKDIPLEEVVLKVCSCALQRDLLLHGRLYISPNWLCFHASLFGKDIKVVIPVVSVQLIKKHKMARLLPNGLAITTNTSQKYVFVSLLSRDSVYDMLRRVCTHLQPSSKKSLSIRKFPEEAECESPEVLIPEMKWRKACSAPASLSLPDSISCISQIPTDSTDSCFPSRKPPGSEAVCEKDALEEEPSTDQELRLWDSRLLKVIFVMICFLVLSSSYLAFRISRLEQQLCSLSWGSPLPRDR
What is the function of this protein?
Participates in the organization ofendoplasmic reticulum-plasma membrane contact sites (EPCS) with pleiotropic functions including STIM1 recruitment and calcium homeostasis.  Constitutive tether that co-localize with ESYT2/3 tethers at endoplasmic reticulum-plasma membrane contact sites in a phosphatidylinositol lipid-dependent manner.  Pre-marks the subset of phosphtidylinositol 4,5-biphosphate (PI(4,5)P2)-enriched EPCS destined for the store operated calcium entry pathway (SOCE).
What are the official names of this protein?
GRAM domain-containing protein 2A, GRAM domain-containing protein 2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Peripheral membrane protein. Note=Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS). Anchored at the ER, PM binding is mediated via GRAM domain and phosphatidylinositol lipid interaction. Localizes to distinct EPCS than GRAMD1A.
Protein: 1106L_ASFK5
Sequence: MLVIFLGILGLMASQVLGLPSNQPTGQLRPTEDPPEEELEYWCAYMESCQFCWDCQDGNCINKIDGSVIYKNEFVRPCSVSRWMDKCMYDLNKGIYHTMNCSQPQSWNPYKYFRKEWKKDEL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-6L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum lumen.
Protein: DDL_WOLSU
Sequence: MNLAVIFGGASYEHEISIVSAISLKKILPALEHFIFVDGNRDFYWIPASEMRSKHFADGIYKKNPKLFLRPGGFYAKGLWGEKRVPFDTALNLIHGGDGEDGKLASLLEFFRIPFIGPRIEASVMSFNKHLTKLYAKERGVKTLPYLLARKNEKREFGNEFPLIVKPLRLGSSIGVSIAKNRQELDYALDVAFEFDEAALLEPFMQGIKEYNLAGCKINGEYHFSIIEEPQKKEFLDFDKKYLDFSRTQKLLKADLSEASERLLKEAFIKLYDDSFEGSLIRCDFFVQNQEVFLNEINPIPGSLANYLFEDFPKILQSLAHNLPKERGIKIDYRYIHQIQKAKGK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAF17_CRYNB
Sequence: MAAPRIAHLAHKSVLELSGPDAQKFLKGLSCKDVEYLAGGYSGFLNASGRVLHTAFVFPRSKNSYLITHESPEDHPAPLTSLLPPFKLRSKVRIKDVTSQWDAWSAWGSDLQGGPSPIRTWKMGSGGASESHWDWEGGVRDLGLRDDEVGCWDLRAGWPHMGRQLLIPKGEKPSLATSHDLGNMDDYELHRMLLGVPEGPTEILPGHALPLESCMDIHGGVDFRKGCFLGQELTVRTYHTGATRKRILPVRLIPLDQTSSSSISDLLSSSPQQSLDEVSTPLDITYHPPSSSATRKPRSAGKILSLHNAVGLALVRLEMAERCWWSGDILRSSVSQWLDSGAGRLTTQVNGKEWGVYVGQGEAYAAALEHMSSSS
What are the official names of this protein?
Putative transferase CAF17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. CAF17 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYP_HALH5
Sequence: MKQSFFLVPTMREVPADADVVSHQLMLRAGMIRQVAAGIYTYLPLARRVIRKIESIVREELDQTGAQEITMPTLHPAELWQESGRWEKYGDELMRLTDRHNRQFALGPTHEEVITSLIRDSINSYKKLPLNVYQIQSKFRDERRPRFGLLRGREFIMKDAYSFHTGGESLDEMYKVMYDAYSRIFRRAGLNVRPVIADSGAIGGKDTHEFMALADVGEDTIAYSDQSDYAANIEMAAVKVNYTRPDEPLLERELVDTGDAKTIRAVAERLSVQEEKIIKSLLVSIDDEWALILLRGDHELNDIKLKHALGASDIRLATEEEVLEVIGTEVGTIGPVDVKGVKVIADHGIKSIVNGVCGANESNKHFIHVNEERDFTVDTYADLRFIQEGDPSPDGKGTIRFAQGIEVGQVFKLGTVYSEKLGATFLDENGKSQPMLMGCYGIGVSRMVAAVIEQHHDEDGIVWPTSVAPFDVHVLALNVKKEEQMKLADSVYHSLQQAGLDVLLDDRPERAGVKFKDADLIGLPLRVAVGKRADEGYVEVKVRKTGEVIEVHADELVPTIQAKLQQLAE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
Protein: GMHA_CHLP8
Sequence: MTRQCNCSEGSCGSGRYEELVLERMLYSARLKETVARRDSDVIAAMATMIAETFRNGGKVLLCGNGGSAADAQHLAAELTIRYRSSVNRPALPAIALSTDTSALTAGANDLGFDEVFSRLTEAYGRPGDLLLGLSTSGNSPNVLKALQTARKLGLKTLALLGGDGGTIRPHADLAVVVPHTGSADRTQECHIAIGHVIVELVESMMGYA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_BACP2
Sequence: MKFALRLLSVITTFVMLIVLIGGALVTKTGSGLGCGRQWPLCHGRFFPEMNPASIIEWSHRMSTGVSTILVLALAVLCWKKISPVFRETKFLVIMSIIFLLLQALLGALAVVFGSNALVMALHFGISLISFASVLLLALLVFEATRSETKLVKPLHIGKKMQFHIYGLITYTYIVVYTGAYVRHTKSSLACSVFPFCSKDGALPAYFNQWVQMSHRAAALLLFVWIFVAMFHAMKHYKEQKQLYYGWIISAILITLQAISGVMSVYSQLALGYALAHSFFISCLFGVLCYFCLLIARFKYESKEPFK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MBTM_MYCBO
Sequence: MSELAAVLTRSMQASAGDLMVLDRETSLWCRHPWPEVHGLAESVAAWLLDHDRPAAVGLVGEPTVELVAAIQGAWLAGAAVSILPGPVRGANDQRWADATLTRFLGIGVRTVLSQGSYLARLRSVDTAGVTIGDLSTAAHTNRSATPVASEGPAVLQGTAGSTGAPRTAILSPGAVLSNLRGLNQRVGTDAATDVGCSWLPLYHDMGLAFVLSAALAGAPLWLAPTTAFTASPFRWLSWLSDSGATMTAAPNFAYNLIGKYARRVSEVDLGALRVTLNGGEPVDCDGLTRFAEAMAPFGFDAGAVLPSYGLAESTCAVTVPVPGIGLLADRVIDGSGAHKHAVLGNPIPGMEVRISCGDQAAGNASREIGEIEIRGASMMAGYLGQQPIDPDDWFATGDLGYLGAGGLVVCGRAKEVISIAGRNIFPTEVELVAAQVRGVREGAVVALGTGDRSTRPGLVVAAEFRGPDEANARAELIQRVASECGIVPSDVVFVSPGSLPRTSSGKLRRLAVRRSLEMAD
What is the function of this protein?
Activates lipidic moieties required for mycobactin biosynthesis.  Converts medium- to long-chain aliphatic fatty acids into acyl adenylate, which is further transferred on to the phosphopantetheine arm of the carrier protein MbtL.
What are the official names of this protein?
Medium/long-chain-fatty-acid--[acyl-carrier-protein] ligase MbtM, Fatty acyl-[acyl-carrier-protein] synthetase, Fatty acyl-ACP synthetase, Mycobactin synthetase protein M.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GLYA_DESVM
Sequence: MDELLIQDPEVGRAVTLEIERQTGKLELIASENFVSAAVRQAQGSVLTHKYAEGYPGKRYYGGCEFVDIAENLAIDRAKAIFGCGYANVQPHSGSQANMGVYFACLKPGDTILGMNLSHGGHLTHGSPVNFSGRLYNVVFYGVKKETGYIDYDEVAALAREHKPTLIVAGASAYPRTIDFARFRAIADEVGAKLMVDMAHIAGLVATGLHPTPIGQAHFTTTTTHKTLRGPRGGMILSDEDNAKTLNSQIFPGIQGGPLMHVIAAKAVAFGEALRPTFVDYQQQVVKNAARLAGCLTAAGYDLVSGGTDNHLMLMDLTAKDITGKDAEHALDKAGMTANKNTVPFETRSPFVTSGVRLGTPALTTRGMKEAEMEKVAAWIVDALANVNNETRLAAISREVEVFARQFPLFAW
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_ACET2
Sequence: MSTPKKDKNNKEVDKTDVKTPVKVRRAKKKICAFCVDKVERIDYKDVAKLKKYISERGKILPRRISGNCAKHQRQLTVAIKRARHIALLPYTAD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RUVC_ACISJ
Sequence: MRILGIDPGLQTTGFGVVDVDGHRLRYVASGTVRTTGRATGLALGDLPGRLKVLFDGVSEVAARYQPSTAAVEIIFVNVNPQSTLLLGQARGAALTALVNANLPVAEYTALQMKKAVVGHGRAAKSQVQEMVRRLLELPGLPGTDAADALGLAITHAHAGAAMARVGEVAQLTRRQHAMYKAGRSY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ACUK_FUSV7
Sequence: MPHEMEENGAEVSDVMSENEDDTETFLKDDEKMTEQSTTDSTTEVKKKYDPKDPLRPRRKKARRACFACQRAHLTCGDERPCQRCIKRGLADACQDGVRKKAKYLHDAPPEALRPVLGPNYNPTPTPSRTNGHRHSSSQSDNLSATGSNFFSQGSTASLPVYSAGAQTPVAIDGLPSFNPQTSPTSFQGPINNAAHTPMNNMMPAGNMDFNALFDPSNPALYNFDLEGLNFGSQYAGWEFGILNKMALGAETPPRENSMSQTPTTEANYAALFGNANNGFDHPMLGADFSGMDQNNQSLYAQGNLQHGLPHAYAIAAGPTSLASPSTDTTASPHSVAGMDGSPNHNFAGIPTVPAATRPRPKHNKAGPKSILGKRQRDSAAIYESVKEPYPYTTGFHNMVAVLRNRLPGNKLLRIAKALGEIRPSFISCTKDLTRQDLVFMEKCFQRTLVEYDDFLQHCCAPTIVCRRSGEVAAVNKEFTALTGWTKDVLLGKEPNLNVNVYSGRSTNGTNTPDHNSQGEMTTPRPQRAMLDLSGGRPQPVFLGELLDDDSVVEFYQDFSQLAFEDSRGKVQRSCRLNKYRAPQDPDQKEPGSQKDAQPGILSSRVTRIDGSHGISRIEKDGKVECTYCWTIKRDVFDIPMMIIINFLPRYLPDQGPQQLAV
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis NECHADRAFT_59099.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CTIP_DANRE
Sequence: MSITPADLSPASSSDHREKLQELLTAVRDLHDTALQELQAKIAKLKKERCLDAQKLSEFHSKNQHLREQQKIQQEKIRQLEDRLRSGPCDRCTVKEKQIKKTNTELEDNNQRNLSVISELEAERKTLTDENRRLSLELERLRRSGSPQNTSSEAEEGMIPDSPLRPLSLPVASKMKRRKEQNHVRYTETPLSLSHPESRQREQSVAFGCNGKGVLVAETCEMDATSVAERDNKRHFRIVVPETCRPDVYPEQVDDVDDDDLHIPSHTEQNQKPELRDCTNILIAGQNDDSPLILRCRPLASQDHQSSIDDVLRTPANSSTCVLTKGKRKHSNGAKKDREISDCRLDADETDIKGIIFASTPANGRLQSKNQETSEIETTQDSKKKCLDGHTPRKSLVQNHHAPFPYDQSWSVDPGADLGQYDTESSPQPEHQARTDLETLDTDCTFVSHSLLLRGQKTTGQSQTTGIGQKANDSLADIFDKTGYGEYESCPQDDSIDLKQDSVYEEEREEDDPEEKPEAAVVFRRPADRKPLVSDSDKSSRNKSFACVEVVRKKDERRKLKGHYCKECEVYYADLPEEEREKKLTSCSRHRYRYIPPSTPENFWEVGFPSTQTCVERGYIKEDEQPDVRIRRRRPYLAMFSPKAKSQKKKH
What is the function of this protein?
Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway.  Functions downstream of the MRN complex and ATM, promotes ATR activation and its recruitment to DSBs in the S/G2 phase facilitating the generation of ssDNA.
What are the official names of this protein?
DNA endonuclease RBBP8.
What is the protein family that this protein belongs to?
Belongs to the COM1/SAE2/CtIP family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with sites of DNA damage in S/G2 phase.
Protein: MZM1_ASPCL
Sequence: MASQTAVAARGAYRQILRATRVAFQNDFRVLIAARQEARQQFDKHRREGIDTPMQINHAKEVADILRHNIVQGVRDGSDEASKWELRIHDDIERGDNDSIKIGGKNVKIEKACSA
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FOLD_SYNY3
Sequence: MTAVPPSCQILDGKALAQKMQGELQRDIAQLVAQGHRSPGLAVLMVGDNPASAVYVRNKEKACEKLGMVSFGKHFSADTDQETLTAAIASLNEDERVDGILVQLPLPDHLDAVKLLHTIDPSKDADGLHPVNLGHLVRGEEGLRSCTPAGVMALLAEYNLDLTGKNAVVLGRSILVGKPLALMLLEKNCTVTIAHSRTQNLADITRQADILVAAIGKPEFVTADMVKPGAIVVDVGINRLDLGEGKSTLVGDVDFAGVAPVASYLTPVPGGIGPMTVTLLLANTVASYRQRLGI
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.