PharMolix/UniProtQA huggingface dataset:
Protein: RP6L1_ARATH
Sequence: MRFDDPMDEFKRNRKMEEDSKKVIDVKVAESDKGFAKFGKAEVPFHIPTLTKPQEEYKILVDNANNPFEHVLLEKSEDGLRFIHPLEELSVMDFVDRNLSEMRPVKPLPLEETPFKLVEEVKDLEDLAAALQSVEEFAVDLEHNQYRTFQGLTCLMQISTRTEDYIVDIFKLWDHIGPYLRELFKDPKKKKVIHGADRDIIWLQRDFGIYVCNLFDTGQASRVLKLERNSLEFLLKHYCGVAANKEYQKADWRIRPLPDVMKRYAREDTHYLLYIYDVMRMELHTMAKEDEQSDSPLVEVYKRSYDVCMQLYEKELWTRDSYLHVYGVQTGNLNAVQLSIVAGLCEWRDRIARADDESTGYVLPNKTLFDIAKEMPIVVAQLRRLLKSKLPYLERNFDAVISVIRRSMQNAAAFEPVVQSLKDRRPETVVEMNIEPKIEKTDTGASASSLSLEKVCVDDSKKQSSGFGVLPLKRKLESDKTVVEKNIEPKIEKTGTEASASSLSSKKVCVDDSKKQSSGFGVLLSKRKFESDNKVKEEVKVSKSKPDKVIIVVDDDDDDDDDESYEQSTKAADALDRVSETPSKGSPSLTQKPKTCNTEVIVLDDDDDSESREDEDMRRRSEKHRRFMNMKRGFLNI
What is the function of this protein?
Acts as an important epigenetic regulator through multiple silencing mechanisms (PubMed:23555312, PubMed:24726328, PubMed:24719467, PubMed:25211139).  Involved in transcriptional gene silencing (TGS).  Plays a role for DNA methylation in the RNA-directed DNA methylation (RdDM) pathway.  Contributes to the methylation status of the retrotransposon SN1.  Required for DNA methylation only at a subset of RdDM target loci (PubMed:24719467).  Plays a regulatory role in RdDM through retention of non-coding RNAs (ncRNAs) in normal cells.  Helps to retain Pol V-transcribed RNAs in chromatin to enable their scaffold function and is required for genome-wide Pol IV-dependent siRNA (24 nt siRNA) production that may involve retention of Pol IV transcripts (PubMed:24726328).  Involved in association with RRP6L2 in the silencing of the solo LTR locus.  Controls levels of ncRNAs from the solo LTR locus.  Seems to function independently of the RdDM pathway (PubMed:23555312).  Functions redundantly with RRP6L2 in the regulation of FLC locus.  Participates in the maintenance of trimethylated 'Lys-27' (H3K27me3) at FLC locus via the regulation of antisense long non-coding RNAs (lncRNAs) and the regulation of diverse antisense RNAs derived from the FLC locus (PubMed:25211139).  Seems not involved in the exosomal RNA degradation (PubMed:24726328, PubMed:25211139).  Can complement the growth defect of a yeast mutant lacking RRP6 exonuclease (PubMed:18285452).
What are the official names of this protein?
Protein RRP6-like 1, AtRRP6L1.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=Also detected in the nucleolar vacuole.
Protein: CUTC_YERPS
Sequence: MTKLEVCCYSVDCAQIAEKAGADRVELCCGQSEGGLTPSVGALMQARETVTIPVHPIVRPRGGDFCYSSNDFTIMKNDIARIRDLGFAGVVVGVLDTDGHIDMPRMREIMSVSGSLAVTFHRAFDMCQNPMIALKQLAELNVARILTSGQQQNAELGLALLKDLVAATKDQGPIIMAGAGVRLTNMQKFIDAGIRELHSSAGRTVPSTMRYRKAGVTMCADSDVDEFSHYCVDGEVVEAMKSLLVMGSPLAKHT
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_HUPLU
Sequence: MAKTLFVFTSFPRGYSRNCLQSFFKKKELGPKKIDDSSLNNHFSFITRKRLISKIRQQNLLETLALWINKYLSGGGHNKKNQSFDYCINYYFESIREVLTSVLQIVQLQPLLEEINELNSFQSIHSIFPSMEDHFSHRHHFSDIKIPYFIHPEILIRIFRRRIQDAPFSHLLRFVFYEYQNIIVLDKSIPLSWKEISKLSTFLWNYYVHEFESTLVSLWKRTFHFNSFPYGALLDRTQSIRKVKHIEKLPHFKKSPRIIILSGNIPLCVKKYSIHYVRYENNLMIALKGTKFLVHKWKCYIIRFWQYYFHCWFKPCRVSPRESSKECLTFLGYILGIRPQIIVVQAKMINNLPITSIISKELCAIIPVFHSIKLLAREKFCNTLGHPIGKLAWTTSEDDDIPNQFNHIWKNIFYYYSGCLNRNGLYQIQYILRFSCAKTLACKHKSTIRVVWKKYGSRRLFPRYSSYKERESPFLSRVYSHKKRFWYLDVIQVDFIADSLQKGRIPEFKTNFTNKKLIKQLPEQTQYDSVIL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns (By similarity).
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSD1_TOXGG
Sequence: MRSYLRFSDRHRQRPTRPRKRVICSSAHFICSRMSPAATAQSPFGISLHSLSFRLLLIFRGSIVAMSRRFVYKLDQAVTAALGPNGRYIAMVGMTASAVLLTFHYKFREVIAATDNVAEIQSPSKLFYLRLLFGRTRSRITGSVMNINIMPALRDPIYRTLASVGGIDTEEIRYPLRSYKCIGHLFARTLKDKEREIEDIGTQSLASPADGVVTALGDVSSERVEQVKGATYSLRAFLGLMPKVTNPEKNTLKFVVLHLKPKNYHHFHAPAKFDVNVLRHMTGETLPVFSSFLKRFNDIFSVNERVVMSGNWKYGCMHMVAVAAYNVGNIRIDKEPSLRTNELRVVLRHLGGDVETRTYSRQPFEYSVGQHVGEFRLGSTIVLIFEAPHNFTWDMKPGQEVRVGQRLGGVGPIRRAQTEDERLFAFY
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
[Phosphatidylserine decarboxylase 1 beta chain]: Mitochondrion. Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side. SUBCELLULAR LOCATION: [Phosphatidylserine decarboxylase 1 alpha chain]: Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Anchored to the mitochondrial inner membrane through its interaction with the integral membrane beta chain.
Protein: PANC_BACMK
Sequence: MKIITTVQEMQQITNELHASGKSIGFVPTMGYLHEGHATLLRKAREENEIVVLSVFVNPLQFGPNEDLDRYPRDIDRDENVAKENGVDYLFYPSVEEMYPAEQTTTVEVVKRTDVLCGKQRPGHFAGVATVLMKLFNITLPTRAYFGMKDAQQVAVIEGFVTDFNIPVTIVPVDIVREEDGLAKSSRNVYLSLEEREEAPHLYGSLCIAKERIEAGERNPEIIMNLVKEHIEKYTKGTVDYADLYAYPSLKAINKIEGRIILAIAVKFENVRLIDNITLMGK
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_BORDL
Sequence: MRKHLNDLYKQIEKFPKTSGCYKMYSKDNKILYIGKAKNLRSRVKNYFSKRTSHKTKILMNNVTNIEIITTNSEYEALLLECNLIKKYKPTYNIKLKDDKGYPMIRITCEKYPRIFKTRKIINDGSEYFGPYVNVKNLDLVLDLINKTFKTKKCKKKSKNPCLYFHMGQCLGVCYREDLEDEYRKEIEQIKHILNGNISKLLNDIEIKMKEVIMKENFEAAIKLKETKKSLIEISQTQIITKIDKLSEDYLYIHKTNSLNTIVILKYKDGKLTEKDIHFDESIYEEDELIEKFITQYYTSPNMIVPDKIHIFKKIDTSNITKLINELKNIKTEIIYKETQDNIKIIEMATSNAKLALITYNHEKNKAIENLKTILEMKKLPKTIEGFDIAHINGYKTVASLVTFKMGKPFKDGYRVYKINSLSNGEIDDCKAIKEVISRRYSKLINEQLKLPDLILIDGGKGQLNAAYSILKGLRIEEKIAICALAKKEEIIFLPNKNQGIKLQKRNSALQVLQNVRDEAHRRANNFNNKLHNNIKLNYTKIKGIGEQKAKKILKVLGTYKDILLLNEDEIATKMKINITMANKIKKFAEEQNLNNKQNNHI
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_MICNA
Sequence: MAYPLQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAAILVLIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVSSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKYFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UD13_HUMAN
Sequence: MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVVLTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNMSLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQREVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
What is the function of this protein?
Lacks UDP-glucuronosyltransferase (UGT) activity but acts as a negative regulator of isoform 1.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A3, UGT1A3, UDP-glucuronosyltransferase 1-3, UDPGT 1-3, UGT1*3, UGT1-03, UGT1.3, UDP-glucuronosyltransferase 1-C, UGT-1C, UGT1C, UDP-glucuronosyltransferase 1A isoform 3.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NU4LM_MAMPR
Sequence: MPYIYMNITLAFVISLIGTLMYRSHLMSSLLCLEGMMLSLFTLNALLSLNMNFTLSTTVPLILLVFAACEAAVGLALLIMISNTYGLDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ASY2_ARATH
Sequence: MVVVSKNNEQQSLILTTELLRTAIFNISYIRGLFPVRYFKDMSVPALDLKMKKLMPMDAESRRLIGWMEKGVYDALHKKHLKKLIFYICETVDGPLIEEYIFSFSYSDSDSQDVRMNINITGINTYGGTLNSTADNSTADMTLNQMSSVDEDFGQNARRSNAFVTYQRFSVYISFHIANYRLCYFFASVQRTILMKLLYYEYVPPDYQPPFFRGCSEEEEAQYVWPKIPLRMEIGNVNSQHHVLTVKVKSVLDPYDPCEDENDNMQDDERSKGPDSLHDDQPCKVFTKPSKLILTENKDADHGEVNEEKLLLITPICEILQDVKQDQVEHQLAKVKDTKGRPASIVQNPILQSHEYDIRRLKARLQRLERHISVPDSPQEGIRKWFAAVSSQLFYKVMEACTRRKPILGDAILSSTVKVQNFNAKICSKLLKKPASIYRKKHFTLNSASLRISGLAGSIFAWAVGFCLFSAQIGHVFVQPKTRSSESKPKVTMEELEEKLTPPSSEPKSAPPSSEPKSAPPSSEPLEKLAVIRRILPEIFAQRCGQRNSSFEAFAQRRTTYDYYNIRLNPREIIFRRLQEESKVALALSSANYFVLSILYRFFRQWSEVSLVRRNSRLTGNPSNEAQSSRSNRIEIPTLLDEPDREGSGGHLAAPEDPVDFLAQFDPLIDLEDAYNTQPQYTEAEVNARLLHEDHVEFDLVPVVSWNTEITAKKTLSTTESVAEVFALCGSGDRPLTCMIPGENERPWNPPRGYVCMYEAYFRQCHLWFPIPSLIISFLNRRHMAFSQLTPAAICNFVAALTFGAEEGYLVNVRCFEEMTTLKAIRSPGYWVVNNRPKHNFLPGPKVSNFKNWEEYYFYVRVDLESYERPFSGRKRMWTEFPDRYRPSPDFPVEFEGVLEAIFRARRRTWKDVTRSRVNRIMGKVRKSFISFAAGLLNMPPPPAPIEEERQPLDGEAAASNPPVSAGPSGVDQVSHEMVNPESQDRMCLEGADVVPAQEIAECDRSQSVQVVEPEVQNITDDRSVVVYAAPPAGEEVNTGLTILDQDKDETVAEPGISRRSREEKGKGGANQSKKRSASEAGLDEAAAPKTFRLSRGETLNSDQFTFKYSGEKFLVRDQEAASHLWRNLMLPGTKDFPNPDDLVLKEGYQKFARSSLETAALANDLIATYDRKLKLKLADREAFDNLKKCADQAKAIYAKDMKEMASLRDAAEIHKAEMSSLNDEVKRLNSREADLQKEFSDLQVALVAVKEHGERECNRLRNDRAAKVARTTKKAQARLDRVKAYLKEQEDLVGPKVDAENQARGAEEIVGILMQRGAKIAASELSGLKELTKRATDEVNALNVIELGDDDLNMSPDQLGFSRQISQVAPVADQHGSNVDLLAEVIRRVSVEETNQTT
What is the function of this protein?
Required for normal meiosis.
What are the official names of this protein?
Meiosis-specific protein ASY2, Protein ASYNAPTIC 2.
What are the subcellular locations of this protein?
Chromosome. Nucleus.
Protein: GON3_SALTR
Sequence: MDLSNRTVVQVVVLALVAQVTLSQHWSYGWLPGGKRSVGELEATIKMMDTGGVVALPEETSAHFSERLRPYDVILKKWMPHK
What is the function of this protein?
Stimulates the secretion of gonadotropins.
What are the official names of this protein?
Progonadoliberin-3, Progonadoliberin III.
What is the protein family that this protein belongs to?
Belongs to the GnRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: TBCD_BOVIN
Sequence: MALSEEPAAGAAEDPVEDPVEDAGEDAALACGAALESFGESAETRELLGHLPAVLADRSAREGALERFRVIMDKYQEQPHLLDPHLEWMLNLLLEFVQNKTSPADLVHLAFKFLYIISKVRGYKTFLRLFPHEVADVQPVLDMFTNQNPKDHETWETRYMLLLWLSVTCLIPFDFSRLDGNLSQPGQERASTMDRILQVAESYLVVSDKARDAAAVLVSKFVTRPDVKQKKMASFLDWSLCTLARSSFQTIEGVIAMDGTLQALAQIFKHGKREDCLPYAATVLQCLDSCRLPDSNQTLLRKLGVKLVQRLGLTFLKPQVAKWRYQRGCRSLAESLQHSIQNPREPVTQAETPDSDGQDDVPEEVESVIEQLLVGLKDKDTIVRWSAAKGIGRMAGRLPKELADDVTGSVLDCFSFQETDSAWHGGCLALAELGRRGLLLPSRLSDVVPVILRALTYEEKRGACSVGSNVRDAACYVCWAFARAYEPQELKPFVAAISSALVIATVFDRDVNCRRAASAAFQENVGRQGTFPHGIDILTTADYFAVGNRSNCFLVISMFIAGFPEYTQPMIEHLVTMKVGHWDGTIRELSAKALRNLAQRAPEHTAREVFPRLLSMTQSPDLHTRHGAVLACAEVARSLHTLATQQGRPVSDFLDEKAMHGLKQIHQQLYDRQLYRGLGGELMRQAVCILIENVALSKMPFRGDAVIDGWQWLINDTLKNLHLISSHSRQHIKEAAVSALAALCSEYHAQEPGEAEAAAQEELVKLYLAELQSPEEMTRCGCALALGALPAFFLKGRLRQVLAGLRAVTHISPKDVSFAEARRDALKAISRICQTVGVRAEGPPDEAVCRENVSQIYCTLLDCLKDYTTDSRGDVGAWVREAAMTSLMDLTLLLGRNQPELIEAPLCQQLMCCLAQQASEKIDRFRAHAARVFLALLHADSPAIPHVPARPELERLFPRAAVASVNWGAPSQAFPRMARLLGLPAYRYHVLLGLAVSVGGLTESTVRYSTQGLFEYMKEIQNDPAALEDFGGTLLQVFEDNLLNDRVSVPLLKTLDQMLANGCFDIFTAQENHPFCVKLLALCKEEIKKSKDVQKLRSSIAVFCGLVQFPGDVRRKVLLQLFLLLCHPFPVIRKNTASQVYEMVLTYDVVPTAVLDEVMAVLSSTAWDAELPVVRAQRNRLCDLLGVPRPQLVPKPAVR
What is the function of this protein?
Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly.  Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB).  Its ability to interact with beta tubulin is regulated via its interaction with ARL2.  Acts as a GTPase-activating protein (GAP) for ARL2.  Induces microtubule disruption in absence of ARL2.  Increases degradation of beta tubulin, when overexpressed in polarized cells.  Promotes epithelial cell detachment, a process antagonized by ARL2.  Induces tight adherens and tight junctions disassembly at the lateral cell membrane.  Required for correct assembly and maintenance of the mitotic spindle, and proper progression of mitosis.  Involved in neuron morphogenesis.
What are the official names of this protein?
Tubulin-specific chaperone D, Beta-tubulin cofactor D, Tubulin-folding cofactor D.
What is the protein family that this protein belongs to?
Belongs to the TBCD family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Lateral cell membrane. Cytoplasm. Cell junction, adherens junction. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localized in cell-cell contacts.
Protein: GRDD_PEPAC
Sequence: MSDIKQMIGKTFMEIADAIETGSFAGKVKVGITTLGSEHGVENLVKGAELAAKDAAGFDIVLIGPKVETSLEVVEVATEEEAHKKMEELLDSGYIHSCVTVHYNFPIGVSTVGRVVTPGMGKEMFIATTTGTSAAQRVEAMVRNALYGIITAKSMGIENPTVGILNLDGARAVERALKELAGNGYPITFAESLRADGGSVMRGNDLLGGAADVMVTDSLTGNIMMKVFSSYTTGGSYEGLGYGYGPGIGDGYNRTILILSRASGVPVAANAIKYAAKLAQNNVKAIAAAEFKAAKAAGLESILAGLSKDTKKASTEEEVKMPPKEVVTGTISGVDVMDLEDAQKVLWKAGIYAESGMGCTGPIVMVNEAKVEEAAKILKDAGIVA
What is the function of this protein?
In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate.  Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine.  By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state.  Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
What are the official names of this protein?
Glycine/sarcosine/betaine reductase complex component C subunit alpha, Protein PC alpha.
Protein: TX313_LYCSI
Sequence: MKFVLLFGVLLVTLFSYSSAEMLDDFDQADEDELLSLIEKEEARAKECTPRFCDCSHDRHSCCRSELFKDVCTCFYPEGGDNEVCTCQQPKHLKYMEKAADKAKKFGGKIKKWFG
What are the official names of this protein?
U3-lycotoxin-Ls1c, Toxin-like structure LSTX-B13.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAND_GEOSW
Sequence: MFRTLMNAKIHRARVTEANLNYVGSITIDADILDAVGMVPNEKVQIVNNNNGARFETYIIPGERGSGVFCLNGAAARLVQKGDIIIVISYAIVPEEKIAQHRPKIAIMDENNRIQQLIVEEPAHTVL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_MYCVP
Sequence: MTDTQVTWLTEESYDRLKAELDQLIANRPVIAAEINDRREEGDLRENGGYHAAREQQGQEEARIRQLQELLNNAKVGEAPKQSGIALPGSVVKVYYDDDEKDTETFLIGTREQGVSDGKLEVYSPNSPLGGALIDAKVGESRSYTVPSGNTVKVTLVSAEPYHG
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: HTPX_YERPS
Sequence: MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGAFVSLLMSKWMALRSVGGEVIERPRNETEYWLLETVRRQSQQVGIAMPQVAIYQAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHVANGDMVTMTLIQGVVNTFVIFISRLIAQIAAGFLSGDRDGESNSPGNPMVYFAVSMVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEAGSMMAFCINGKSKTFSELFMSHPPLDKRIEALRSGQYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSCL_JANMA
Sequence: MGMMQEFKEFAVKGNVVDLAVAVIVGAAFGKIVDSLVQDVIMPVVGKIFGGLDFSNYYIALNNQDPNLTLVEAKKLGAVLAYGNFITIALNFIILAFIIFQMVRLLNKLKRTEPPAPEEPAAVPEDIALLREIRDSLKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CEC1_CERCA
Sequence: MNFNKVFILVAIVIAIFAGQTEAGWLKKIGKKIERVGQHTRDATIQTIAVAQQAANVAATARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-1.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURI_SHESA
Sequence: MSQPILVFDSGIGGLSVLAEIRKLLPHHDYCYLFDNARLPYGELEEQELISGCVALIDQVVERTHAAIVVVACNTASTVVLPALRATLSIPVVGVVPAIKPAAQLSKSKRIGLLATPGTVKRHYTYELISQFADDCHVELFGSSELVLMAEQKIATGQLDMVRLTQVLSPIVEADLDVLVLGCTHFPMLRDELQQVLGQGVTLLDSGEAIAKRVKTLLAETKSDEQVQEEDAHSNLLMQAFYTKAEISEGLATTLVDCGFSTLERITTINSNG
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: TRHO_BACCN
Sequence: MAIKKPYRVLLYYMYTTIENPEEFAAEHLQFCNSLELKGRILVAKEGINGTASGTTEQTEKYMEAMKNDPRFAGIVFKVDEADGHAFKKMHVRPRSELVTLRLEDDINPKELTGKYLEPKEFYEAMQQEETIVIDARNDYEYDLGHFRGAIKPEIKSFRELPNWIKENKEVLEGKKILTYCTGGIRCEKFSGWLVREGFEDVSQLHGGIVTYGKDPEVQGELWDGQCYVFDERIAVPVNQKEHVIVGRDHFTNEPCERYVNCANPECNKQILCSEENEAKYLRACSHECRVHPRNRYVKEHELTEEQVAAALEKIEAENQVKLG
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: CAINT_THOIN
Sequence: MRQNTMTIIFIVFIVTFASLTIYGAEASEANFLERRADCLAHLKLCKKNKDCCSKKCSRRGTNPEQRCR
What is the function of this protein?
This toxin stabilizes ryanodine receptor 1 (RyR1) opening in a long-lasting subconductance state (55% of the full conductance state) (PubMed:28159581).  Furthermore, it triggers calcium release from sarcoplasmic vesicles (45. 3 nM are enough to induce a sharp release, and 50% of the total calcium is released after toxin (100 nM) addition) probably by acting as a cell-penetrating peptide (CPP) (PubMed:28159581).  In addition, it has been shown to dose-dependently stimulate ryanodine binding to RyR1 (EC(50)=17. 4 nM) (PubMed:28159581).  It also augments the bell-shaped calcium-[3H]ryanodine binding curve that is maximal at about 10 uM calcium concentration (PubMed:28159581).  It binds a different site as ryanodine (By similarity).  It acts synergistically with caffeine (By similarity).  In vivo, intracerebroventricular injection into mice induces neurotoxic symptoms, followed by death (By similarity).
What are the official names of this protein?
Intrepicalcin, ViCaTx1.
What is the protein family that this protein belongs to?
Belongs to the scorpion calcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: F16PA_PSE14
Sequence: MSRVTLSRYLIEQTRSNNTPADLRFLIEVVARACKEISHAVSKGALGGVLGSMGTENVQGEVQKKLDVISNEILLEANEWGGHLAGMASEEMDNAYQIPGKYPKGAYLLVFDPLDGSSNIDINAPVGTIFSVLRCPNEYLSQNEALNEKAFLQPGTEQVAAGYAIYGPQTMLVLTLGDGVKGFTLDREMGSFVLTHEDIKIPESTQEFAINMSNQRHWEAPVQRYVNELLAGEEGPLKKNYNMRWVAAMVADVHRILTRGGLFMYPRDSREPSKPGKLRLMYEANPMSFLVEQAGGASTDGHQRILDIQPEGLHQRVAVYLGSKEEVERATAYHKE
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPH_ECOSE
Sequence: MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALRDSWYDLDAHYDALETRFWQFYPRMMAQASHKAL
What is the function of this protein?
Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP.
What are the official names of this protein?
Acyl carrier protein phosphodiesterase, ACP phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the AcpH family.