PharMolix/UniProtQA huggingface dataset:
Protein: PLSX_SYNFM
Sequence: MKIAVDAMGGDHAPEALIEGALLAGPQCSADILVIGNEARLSSLLAHSGDSTSLKVVHAPQVIGMGEAGPMALRRKREASLTIAMRLLAENEVDAVVSAGNSSAVVSAARHLVGLIPGLRRPAMAVPLPTPSGKLLLLDAGAHAEATAIHLAQSAVLAHCYLKIEEGLNRPRIGLLNIGHEPAKGNRAVQRAFALLRRCSLEFTGNVEPNDLFAGKVDAVICDGFVGNVLLKMYEGFSETVCRFLESLANHDGRDFSGGAGRILERFRRDYHYEFVGGAPLLGIRKTVVAAHGRSRATAIANAIRLACRLQEARVFERLAGIVEEDGALTELRHQNTLLMIDQLKDKWGFAHR
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ADE_SCHPO
Sequence: MSNLPIYNFIRKLPKCEHHVHLEGCLSPDLVFRLAKKNGITLPSDDAAYTTPSTLLASYEHFGCLDDFLRYYYIAVSVLIEASDFEALAYEYFSIAHSQGVHHAEVFFDPQTHTSRGISYDVVVSGFSAACERANRDFGMSTNLIMCFLRHLPSEAAHETFAEALKRNDFENGIVAGVGLDSSEVDFPPELFQEVYKLAAEKGIRRTGHAGEEGDPSYIRSGLDNLSLQRIDHGIRLVEDKELMKRVAEENIMLTMCPLSNLKLRCVNSIAELPVREFLEAGVPFSINCDDPAYFGGYTLENYFAIQKHFNLTVKEWVFIANAAINGSWISGKRKEELLSSVQKCVKEYTAEIQQPKTLETAVEVQA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.  Also exhibits a low activity towards N(6)-substituted adenines that are commonly known as the plant hormones cytokinins.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COPB_PSEUB
Sequence: MTVLNRLHVCSLLAVSSLGMLPVGVFAAEAAMPGVDHSQMQGMDHSKMQGMDHSQMQGMDHSKMQGMDHSQMQGMDSDMTTMAPSKPAAPTQSRTPIAPVTDANRAAVYRSAKGHTVHDEAANYFLLFDQLEWQDADNGSVLNWDVNGWVGGDIDRLWIRSEGERTNGKTESAELQALWGHAISPWWDLVGGVRQDFKPGSPQTWAAFGLQGLALYNFEAEATAFLGEGGQTGLRLEGDYDILLTNRLILQPTAEVNFYGQSDPQRGIGSGLSETEVGVRLRYEIRREFAPYIGVTWNRSYGNTADFAREEGEDRSEARLVLGVRMWF
What is the function of this protein?
Exact function not known.  Possibly mediates copper resistance by its sequestration in the outer membrane.
What are the official names of this protein?
Copper resistance protein B.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: PROB_PSEAE
Sequence: MRDKVTGARRWVVKIGSALLTADGRGLDRNAMAVWVEQMVALHCAGIELVLVSSGAVAAGMSRLGWVSRPSAMHELQAAASVGQMGLVQAWESSFALHGLQTAQVLLTHDDLSDRKRYLNARSTLRTLVELGVVPVINENDTVVTDEIRFGDNDTLAALVANLVEADLLVILTDRDGMFDADPRNNPDAQLIYEARADDPQLDAVAGGSAGALGRGGMQTKLRAARLAARSGGHTVIVGGRIERVLDRLRAGERLGTLLTPDRSRKAARKQWLAGHLQMRGTLVLDDGAVKAVSQDHKSLLPVGVKAVQGSFRRGEMVVCVDQGGREVARGLVNYSALEAQKILGQPTDAIEALLGYVDGPELVHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2947_PHOPR
Sequence: MKVYECCELIRKTYAQIGGGDLGYIPNAIHCAVKTFDFIAANEELPKDVRERAAFAAANLLMSDFED
What are the official names of this protein?
UPF0253 protein PBPRA2947.
What is the protein family that this protein belongs to?
Belongs to the UPF0253 family.
Protein: OTC_LEPIC
Sequence: MSESNVKHLISWEDWSDSEILDLLDFAIHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLDWMASNFQLSDIDLEARYLSRNVSVIMARLKKHEDLLTMRNGSQVPLINGCDNMFHPCQSLADIMTIALDKPEIPLNQIQLTYIGVHNNVVNSLIGITSALGIRLTLVTPIAEKENIHSQTVERAKAKGTLSWEENLKKAIQNADYVYTDTWLDMEFFNDPSYADKKKQRMELMMPYQINSSLLEKTNAKVMHDMPIHAGYEITREVVLGPRSIIFQQAENRLDAQKAVILKLLEA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIRC_STUST
Sequence: MTVARHAVSRLGLALASFLLFPLALAAAPAAERQATLDHLLLQDCGSCHGLRMTGGLGPALTREALAGKPRDSLIATVTHGRPGTAMPGWNALLDEQDIAYLVDRLLEGYPKP
What is the function of this protein?
Monoheme c-type cytochrome.
What are the official names of this protein?
Cytochrome c55X.
Protein: 3MGH_BACC2
Sequence: MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTSGPGKLCRALGITLKERGLSLQSDTLHIELVPKDEHISSQYKIAAGPRINIDYAEEAVHYPWRFYYKGHPFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: ERA_MARMM
Sequence: MSDTPKRCGFAAVIGSPNAGKSTLVNALVGEKVTIVTHKVQTTRFAVRGVALAGETQIVLVDTPGVFAPKTRLDKSMVAAAWSGAGEADTIMHVVDAGARARMEHGGAKSGDSRMVEDDDRVTEGLKKTEQKAILVLNKVDLMPRDQLLAMSQELYETGVYSEVFMISAKTGSGVPQLREFIAGLMPEGVWHYPADQVADLPARILAAEITREKVYLRLHEELPYASMVETEVWKKLRDGSLRIEQSIIVERETQKPIVLGKGGSAVKSIGEASRKELEEVLGCKVHLFLNVKVDAKWMARRSHYKDVGLDFDV
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: SIMC1_MOUSE
Sequence: MEDFIVISDDSGSESSAGTRSGRARRLRRALSRTPGALPRRTVDFIDLTRENRARTKDRNGLCVIDLTRNEEENRPIATLDLTLEPVASSQKEPTSLQTCTSLSGKEVMEAHEDRGSQPAAQRIINNDPVDLDLLEENLFEGSRPPTSISQDSVYPPEPNCSSITYKGDLSFLTSLQLSSDVSSFSSTSNQRASLPCPQQDVPCQSQGLLCPLQALSCPQTASPCPPRASSCPPQALSCPPQALSCPSQTLQCQLQALPQPPQEVPCSTQNVPCPQQNMPSTPQGLSWHPRHTLYPYQDTLGLPQDVPGRPQNMSYPQDVTQLQDMPWSLHDMPLSLQDVLQSLQDVPPLLGDVPPSPEVMQLPGYVTQTSRDVIQSPAGVTQSLGSMMQSPGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVTQSLRSVMQSSGSVMQSPGGVTQSLRSVTQSPGGVMQSPGGVMQSPRDVMQSPRDVMQSPRDVMQSPRGVTQSLGSMMQSPGGVMQSLRSVMQSSGGVTQSLRSVMQSPGGVMQSPGGVTQSPRGMIKSPGMMLSPGDVIQSLNSVPQSSRDRMQSAGHVPSASGDAIQSPGGMSPTSRDRMQSPGGVSLATEDSIQLPGGVPLSSDVIQSQGGVPLSSKDRMQSPGGVPPSSGDMIQSQGGVPQSLGDAIQSAGGVPQSSGDAIQSPGGVSLATGDSIQLPGGVPLSSGDVIQSQGGVPRSSRDRMQSPGGVPPSSGGVIQSPGGVSPASGDAIQSPGSVLPASGDAIQSAGGVLLASGDAIQSPRSVPQSPSGTLRSPGNMSESLGDTPNLSGDVSNSPQALLDLARDRPKSSPNDVQNRDTPMDISASSSSSCSANPQSRQSEFKLDKVPWLTITDSSARREKSLPQLANPGSAQIQGQIPQVGVYNRPCLHRLKYFLRPPVHHLFFQTLIPDKDTRESKGQKLEPIPHRRLRMVTNTIEENFPLGTVQFLMDFVSPQHYPPREIVAHIVQKILLSGSETVDVLKEAYMLLMKIQQLHPANAKTVEWDWKLLTYVMEEEGQTLPGRVLFLRYVVQTLEDDFQQILRRQRQHLQQSIANTVLSCDKQPHNVRDVIKWLVKAVTENELTPPQDETQTSPRTGVLKTSSDHLSPRPNQNKNTNQLIVCQLQRMLSIAVEVDRTPTCSSNKIAEMMFGFVLDIPERSQREMFFTTMESHLLRCKVLEIIFLHSCETPTRLPLSLAQTLYFLNNSTSLLKCQSDKTQWQTWDELVEHLQFLLSSYQHVLREHLRSSVIDRKDLIIKRIKPKPQQGDDITVLDVEKQIEAFRSRLVHILGEPLVPQLQDKVHLLKLLLFYAADLNPDTEPASEH
What is the function of this protein?
Inhibits the protease activity of CAPN3.
What are the official names of this protein?
SUMO-interacting motif-containing protein 1, Platform element for inhibition of autolytic degradation.
Protein: ZN524_HUMAN
Sequence: MDTPSPDPLPSPLPGEEEKPLALSPPVPRGRRGRRPGGATSSNRTLKASLPRKRGRPPKSGQEPPLVQVQGVTAPVGSSGGSDLLLIDDQGVPYTVSEGSAAGPEGSGPRKAPHFCPVCLRAFPYLSDLERHSISHSELKPHQCKVCGKTFKRSSHLRRHCNIHAGLRPFRCPLCPRRFREAGELAHHHRVHSGERPYQCPICRLRFTEANTLRRHAKRKHPEAMGVPLCAPDPGSEPPWDEEGIPATAGAEEEEETEGKGEPA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 524.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIFE_BRADU
Sequence: MSSLAATVQDIFDEPGCAKNGSKSEAERRNGCTRQLQPGSAAGGCAFDGAKVALQPFTDVAHLVHGPIACEGNSWDNRGAASSGSDLWRTAFTTDLSETDIVFGGEKRLCKAIKEIIDKCDPPAIFVYQTCIPAMIGDDINAVCKAASRRFSKPVIPINSPGFAGSKNLGNKLAGEALLDYVIGTREPDYTTPYDINLIGEYNLSGELWQVKPVLDELGVRILCCISGDGKYREVASSHRARAAMLVCSKSMINVARKMEQRYGIPFFEGSFYGIQDSSESLRQIARLLVERGAPADLLGRTEAVIAREEARAWAAIQPYKPRLEGKRALLMTGGVKSWSVVSALQEAGLELVGTSVKKSTMEDKERIKELMGQDAHMIDDMTAREMYKMLKDAEADIMLSGGKSQFVALKAAVPWVDINQERCHAYMGYAGIVKLVEEIDNSLSSPMWEQLRRPAPWEALAKAREQMQSMAAIAGDPVLAETARRARNICVCNRVDLGTIEDAISVHGLRSVAAVREHTNAAGGCCQGRIEDMLMSEPSDMRQAAE
What is the function of this protein?
This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).
What are the official names of this protein?
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: VIME_BOVIN
Sequence: MSTRSVSSSSYRRMFGGPGTASRPSSTRSYVTTSTRTYSLGSALRPTTSRTLYTSSPGGVYATRSSAVRLRSGVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGDLYEEEMRELRRQVDQLTNDKARVEVERDNLAEDIMRLREKLQEEMLQREEAESTLQSFRQDVDNASLARLDLERKVESLQEEIAFLKKLHDEEIQELQAQIQEQHVQIDMDVSKPDLTAALRDVRQQYESVAAKNLQEAEEWYKSKFADLSEAANRNNDALRQAKQESNEYRRQVQTLTCEVDALKGTNESLERQMREMEENFSVEAANYQDTIGRLQDEIQNMKEEMARHLREYQDLLNVKMALDIEIATYRKLLEGEESRISLPLPNFSSLNLRETNLDSLPLVDTHSKRTLLIKTVETRDGQVINETSQHHDDLE
What is the function of this protein?
Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
What are the official names of this protein?
Vimentin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Cell membrane.
Protein: PYRG_LACH4
Sequence: MTKYIFVTGGVVSSLGKGITASSLGRLLKNRGLKVTMQKFDPYINIDPGTMSPYQHGEVYVTEDGTEADLDLGHYERIVDVRTSKYSNVTTGKIYQEVLEKERRGDYNGATVQVIPHITDMIKKKIMRAALTTDSDVIISEIGGTVGDMESTPFMEAIRQMRREVGEENVMYIHCTLVPLLHAAHEMKTKPTQHSVAELRSIGIQPNMLVLRAEQPIDQEHKNKISTFTDVPVDRIIESIDAPSLFDVPLAFQKQGMDQKVCDFLHIDSPKPEADMEAWKKLDDRAKNLKHHTKITLVGKYVELEDAYISVTDALQHAGYLYNTKIDVDKVQAEDITEDNIAKIMEGSDGLIVPGGFGTRGLEGMITAIKYARENDIPFLGICLGMQMASVEFARDILNLEDANTTEAEPHCKNNIIDIMADKRDEENIGGTLRLGLYPAALKKGTKTREAYGDQDVIQERHRHRFEFNNKYREAFEKAGMVFSGVSPDNHLVEIIELPKKKFFIAAQYHPEFLSRPQRPEGLFKSFIGAASGLPEQEF
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: EDNRB_PIG
Sequence: MQPLRSLCGRALVALIFACGVAGVQSEERGFPPAGATPPALRTGEIVAPPTKTFWPRGSNASLPRSSSPPQMPKGGRMAGPPARTLTPPPCEGPIEIKDTFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIIIDIPINVYKLLAEDWPFGVEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEALGFDMITTDYKGNRLRICLLHPTQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYDQNDSNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKSCLCCWCQSFEEKQSLEEKQSCLKFKANDHGYDNFRSSNKYSSS
What is the function of this protein?
Non-specific receptor for endothelin 1, 2, and 3.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Endothelin receptor type B, ET-B, ET-BR, Endothelin receptor non-selective type.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=internalized after activation by endothelins.
Protein: CB081_RAT
Sequence: MSHEGSRQARDRGVTRSKAEKARPPTQPVPQVDIVPGRLNEAEWIAFMSLEEGEDIVGDILADLVTRVMECAFKVYLTQQCVPFTISQAREAMLQITEWRFLARDEGESAVAEDPTWGEDEEPLACTTDAWAQGSVPVLHAPAPVGVEEHFHNEEPGNPDQFLIDSSWLGRESQEPTQSSEPSAEPRVNPRPTPAMEVFEEAEPRDALEVPHRQESILTVPSKESLRPTLEVQTVHSPQLSPKLSQVVSLQTCERTGSSFGSHLSLQDLYHCVPQPDAAGDRLNLKNKGQLCRSSIGSADRSLLSVPTPDGPSPFLQPGGMERRPSHKTPTMRLDPSRLPRHWVRPVAEVLIPDLEARPLEIYRVRPRKSQVGASASESQALGSRTHSKLQVSIPRFPLKRCATFRSSGPDPTLNLAQSSPSFGSNLPFLSPGFRFLARNLVPPDVASAPSPKLWPRAKWPSGWEREAEQLGELWAGRTRVPPQGQEPVEDSVSEDSGWPLAVPQVLEATSQVLWKPMVISENMKLVPGVSMWNRGTQELLNPAAIQEEAEEGTPQAPEQQPIQTGVSKPQVIMKQLRNETPKAWLLPTKPVPHSGS
What are the official names of this protein?
Uncharacterized protein C2orf81 homolog.
Protein: YA280_ASPFU
Sequence: MKFSPAYLLAFAPIVAAHFRLQYPTSRGFNADTMANFPCGDLAQSSNRTQVSLSSGSFPVALRMGHDETAVEVLLALGNDPGTNFNITLHPTFRIEGLGEFCLPNVVFDESVLGTKITDGMNATLQVQSNGDPSGGLYACADIQFSTTAQDEKPSSCTNNTGISAIAFTGAAAERNANESTADGQAQSGSSGSSSDSGSHSGHSSATQTSSTTASSTAGAVALETAAWGILGAAVVGGLAVL
What are the official names of this protein?
Uncharacterized protein AFUA_6G02800.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: MSS11_KLULA
Sequence: MAGPGARKSNASNTPQDKKMKGDSIQDQKNKQYNSGDVVEPFVSDAMAKNSKQLLYAHIYNYLVHNQHHDTAKKFLQEANVPLSKAVPQHSLNGDKLLNSKMLMNSPDTFLFEWWQSLWALNQYVETTPIENLTSLKPFNDRIVPILPQVPPQEMLSRVVRTGPIAPAMGFAGNIVPQQQQQQQQQQQQQLQQQQQQQQHFRTMTSPGSGNTPYATNANSFPAGVRVPQPQGSFQPVLGTTPNAGTNAGLGVNPYHAATLGSSKSTPKPQNTSVGSKNKQTKKSSATNKDSGANTKPRANGESKQFKGVNSSSKVKKPSPSGSQQVQANWTKLQQKQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQHQQQQQHQQQQQHQQQQQQIRMQYQKMMTLMQHQQNQQNQQHHQLGNQNILPGQGDPSDNSSPSQQYLQQQRAYENMVKSQQQDQPMNKDHFAMSLQTQQPQSFDSYAMPATMGPQASSQPLDNNKKSEPLSKIDVTNNQDFNTFSGGSNNKLNFGQFDMSGLGNEFMGGRKQ
What is the function of this protein?
Transcription factor that regulates pseudohyphal differentiation, invasive growth, floculation, adhesion and starch metabolism in response to nutrient availability.
What are the official names of this protein?
Transcription activator MSS11.
What is the protein family that this protein belongs to?
Belongs to the MSS11 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ILVD2_RHILO
Sequence: MRQAAPPAARMRMDAKVISKAKLPSRHVTVGPARAPHRSYLYAMGLSAAEIAQPLVGVASCWNEAAPCNISLMRQAQVVKKGVAAANGTPREFCTITVTDGIAMGHQGMKSSLVSREVIADSVELTMRGHCYDALVGLAGCDKSLPGMMMAMVRLNVPSIFIYGGSILPGSYRGRQITVQDVFEAVGQHSVGTIGDAELLEIEQAACPSAGSCGAQFTANTMATVAEAIGLALPYSCGAPAPYEMRDRFNFASGEKIMELIAKNIRPRDIITLKALENAATVVSATGGSTNAALHLPAIAHEAGIKFDLFDVARIFEKTPYIADLKPGGKYVAKDMFEAGGIPLLMKTLLDHGYLHGDCLTVTGRTLAENMEHVAWNEHQDVVRPANRPITQTGGVVGLKGNLAPEGAIVKVAGMTELKFSGPARCFDSEEECFEAVTQRNYREGEVLVIRYEGPRGGPGMREMLSTTAALYGQGMGGKVALITDGRFSGATRGFCIGHVGPEAAVGGPIGLIRDGDVISIDAVNGTIEVALSDSELAARAKTWKARTTDYQSGAIWKYAQTVGSARDGAVTHPGGAKETHCYADI
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase 2, DAD 2.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ITGBL_XENLA
Sequence: MHAGAFINFVWALSLVSLLAAVPPSPSFSLKNLPSTACRLPPAVSEKRCRTPDGSICSGRGSCDCGICLCEVKEAGKYYGPLCECHDWVCHTYDGQVCAGHGQCDCGVCKCDVGWSGEACQYPTTCDLTRKKSNEMCKNSQAVICSNAGTCQCGRCKCENSDNSGLIYGKYCECDDTECFDDETQEICGGHGKCYCGNCYCEAGWHGDKCEFQCDITPWEIKKRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGDTCECDERNCKSVYDRYSDDFCSGHGQCNCGRCDCKDGWTGRKCEHPRACALSIEESKKKCQGSASQPCSGRGKCECGQCTCFPPGDSKVYGKNCECDDRQCEDLEGKICGEHGTCSCGRCICEAGWFGKLCQHERKCNMTEEESKSQCESDDGILCSGKGSCHCGKCICSPQEWYVSGEFCECDDRDCDKHDGLICTGNGICNCGNCECWEGWNGNACEIWLGSEYP
What are the official names of this protein?
Integrin beta-like protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: GPNMB_RAT
Sequence: MESLCGVLVFLLLAAGLPLQAAKRFRDVLGHEQYPDHMRENNQLRGWSSDENEWDEQLYPVWRRGEGRWKDSWEGGRVQAALTSDSPALVGSNITFVVNLVFPRCQKEDANGNIVYERNCRSDLELASDPYVYNWTTGADDEDWEDSTSQGQHLRFPDGKPFPRPHGRKKWNFVYVFHTLGQYFQKLGRCSARVSINTVNLTVGPQVMEVIVFRRHGRAYIPISKVKDVYVITDQIPIFVTMYQKNDRNSSDETFLRDLPIFFDVLIHDPSHFLNYSAISYKWNFGDNTGLFVSNNHTLNHTYVLNGTFNFNLTVQTAVPGPCPSPTPSPSSSTSPSPASSPSPTLSTPSPSLMPTGHKSMELSDISNENCRINRYGYFRATITIVDGILEVNIIQVADVPIPTPQPDNSLMDFIVTCKGATPTEACTIISDPTCQIAQNRVCSPVAVDELCLLSVRRAFNGSGTYCVNFTLGDDASLALTSALISIPGKDLGSPLRTVNGVLISIGCLAMFVTMVTILLYKKHKTYKPIGNCTRNVVKGKGLSVFLSHAKAPFSRGDREKDPLLQDKPWML
What is the function of this protein?
Could be a melanogenic enzyme.
What are the official names of this protein?
Transmembrane glycoprotein NMB.
What is the protein family that this protein belongs to?
Belongs to the PMEL/NMB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Melanosome membrane; Single- pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein: GATC_RHIL3
Sequence: MSVDLATVKRVARLARIAVSEDEANRMVGELNGILGFVEQLSEVNVDGVEAMTSVTPTAMKKRTDEVTDGSKAADIVANAPVTDHNFFLVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CRTB_ENTAG
Sequence: MEVGSKSFATASKLFDAKTRRSVLMLYAWCRHCDDVIDDQVLGFSNDTPSLQSAEQRLAQLEMKTRQPMRIQMHEPAFAAFQEVAMAHDILPAYAFDHLAGFAMDVHETRYQTLDDTLRYCYHVAGVVGLMMAQIMGVRDNATLDRACDLGLAFQLTNIARDIVEDAEAGRCYLPAAWLAEEGLTRENLADPQNRKALSRVARRLVETAEPYYRSASAGLPGLPLRSAWAIATAQQVYRKIGMKVVQAGSQAWEQRQSTSTPEKLALLVAASGQAVTSRVARHAPRSADLWQRPV
What is the function of this protein?
Involved in the biosynthesis of carotenoids.  Catalyzes stereoselectively the condensation of two molecules of geranylgeranyl diphosphate (GGPP) to give prephytoene diphosphate (PPPP) and the subsequent rearrangement of the cyclopropylcarbinyl intermediate to yield 15-cis-phytoene.
What are the official names of this protein?
15-cis-phytoene synthase, Phytoene synthase, PSase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
Protein: IF1_SYNAS
Sequence: MAKEEPIEVEGRVIEPLPNAMFRVELENGHRVLAHISGKMRMHFIKILPGDKVTVELSPYDLTRGRIIYRTK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_KORVE
Sequence: MLMPKKVKYRKQQRGRMRGKAWRGSELSFGDFGLKVLEPGWISDRQIEASRVAMTRFIKRGGKIWIRLFPDKPVTKKPAETRMGKGKGAPDHWVAVVRPGKILFEMEGVSVTDAAEAMRLAAHKLPLRTKFVARETSAH
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RR14_STIHE
Sequence: MAKKNMIQRELKRQKCVLKYETRRQLLKKQITLASTLREKLMLHRQLQKLPRNSSAVRLRNRCMITGRSRGYHRDFGLSRNVLREMAHQGLLPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DNLJ_SHIBS
Sequence: MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELCELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGVPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKLAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: EFP_BART1
Sequence: MKINGNEIRPGNVIEHQGSLWVAVKCNAVKPGKGGAFNQVELKNLLDGTKLNERFRAAETVERVRLEQKDFTFLYQQGDALVFMDSESYEQLELQKDFVGERAAFLQDGMTVTVELYQEKPIGISLPDQVAVTIVEADPALKGQTVTSSYKPAILENGIRILVPPFMNAGERIIVDTNELIYLRRANEKDK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_BACC3
Sequence: MPKVTVYNQTGSQVGEIELAEAIFGIEPNEAVLFEAVMMQRASLRQGTHKVKTRSEVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGTVFGPTPRSYAYKLPKKVRRLAIKSALATKVVENNIVVLEDLVLNAPKTKDMLAVLKGLTVEKKALIVTADANESVELSARNIPGVTVITADGVNVLDVLHHDKLIMTKAAVEKVEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS20_BRUC2
Sequence: MANTPSAKKAVRKIAARTEINKSRRSRVRTFVRKLEDALLSGDKQAAEVAFKAVEPELMRAASKGVVHKNTAARKVSRLAKRVKALNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.