PharMolix/UniProtQA huggingface dataset:
Protein: BRO_DROME
Sequence: MHHHQNLGDAAAMNGMIPPYEAMAMYEQPKPRFIFKMPRVVPDQRSKFDSDELFRRLSRESEVRYTGYRERAMEERRMRFVNDCRKGYAEISMVASGTNLQLYFNANHNPYAQEQDCDFERERGKVHLRSSFIMNGVCVRFRGWVDLDRLDGAACLEFDEQRAQQEDAQLQEQIQSYNQRMAESRRIYHTPQTPPEDHHHRGGPGLPRGPMGW
What is the function of this protein?
Regulates the DNA-binding properties of Runt.
What are the official names of this protein?
Protein brother.
What is the protein family that this protein belongs to?
Belongs to the CBF-beta family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_ONCMY
Sequence: MANLRKTHPLLKIANDALVDLPAPSNISVWWNFGSLLGLCLATQILTGLFLAMHYTSDISTAFSSVCHICRDVSYGWLIRNIHANGASFFFICIYMHIARGLYYGSYLYKETWNIGVVLLLLTMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGGALVQWIWGGFSVDNATLTRFFAFHFLFPFVIAAATVLHLLFLHETGSNNPAGINSDADKISFHPYFSYKDLLGFVAMLLGLTSLALFAPNLLGDPDNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLFSILVLMVVPILHTSKQRGLTFRPLTQFLFWALVADMLILTWIGGMPVEHPFIIIGQVASVIYFTIFLVLSPLAGWAEIKALQWA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: B3GT3_ARATH
Sequence: MSTKIKGELFPSRSLVSKKWTFLLCFGSFCFGILFTDRMWIIPESKDMPRPSVSTEAERLKLISEGCDPKTLYQKEVNRDPQALFGEVSKTHNAIQTLDKTISSLEMELAAARSAQESLVNGAPISNDMEKKQLPGKRRYLMVVGINTAFSSRKRRDSVRTTWMPSGEKRKKLEEEKGIIIRFVIGHSATAGGILDRSIEAEDKKHGDFLRLDHVEGYLELSGKTKTYFSTAVSKWDAEFYVKVDDDVHVNIATLGETLVRHRKKHRVYLGCMKSGPVLSQKGVRYHEPEYWKFGENGNKYFRHATGQLYAISRDLASYISLNQHVLHKYANEDVTLGAWFIGLDVTHIDDRRLCCGTPPDCEWKAQAGNICVASFDWTCSGICRSADRIKEVHKRCGEPENAIWKARF
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal glycosyl residue.
What are the official names of this protein?
Probable beta-1,3-galactosyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: GET1_PARBD
Sequence: MPSLLISVLFLHIAIYIINTIAASTIDSLLWLIYMKLPTSASCIAREQHQMKLEVVQLKREMNATSSQDEFAKWAKLRRRHDKALEEYEVKNKQFSRFKSFFDVAVKALRWAGTSGLIVFLQFWFSKTPIFTLPPSWIPWQVEWVLSFPRAPMGTVSIQVWGGACAVVVALIGEAIGATVRYLYASKDSMEAIKVGAGAVEKEKKRQ
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein GET1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: FTHS_STRA5
Sequence: MKTDIEIAQSVALKPIAEIVEQVGIGFDDIELYGKYKAKLSFDKIEAVKSQKVGKLILVTAINPTPAGEGKSTMSIGLADALNKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELDIDQRRVIWKRVVDLNDRALRQVIVGLGSPVNGIPREDGFDITVASEIMAILCLATDLSDLKKRLSNIVVAYSRNRKPIYVKDLKIEGALTLILKDTIKPNLVQTIYGTPALVHGGPFANIAHGCNSVLATSTALRLADYVVTEAGFGADLGAEKFLDIKTPNLPTSPDAIVIVATLRALKMHGGVSKEDLSQENVEAVKRGFTNLERHVNNMRQYGVPVVVAINQFTADTESEIATLKTLCSNIDVAVELASVWEDGADGGLELAQTVANVIETQSSNYKRLYNDEDTIEEKIKKIVTKIYGGNKVHFGPKAQIQLKEFSDNGWDKMPICMAKTQYSFSDNPNLLGAPTDFDITVREFVPKTGAGFIVALTGDVLTMPGLPKKPAALNMDVLEDGTAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ABRAL_COTCO
Sequence: MNVEHEISLLVEEIRRLGTKNADGQVSVKFGVLFADEKCANLFEALVGTLKAAKRRKIVTYQGELLLQGVHDNVDIVLLQD
What are the official names of this protein?
Costars family protein ABRACL, ABRA C-terminal-like protein.
What is the protein family that this protein belongs to?
Belongs to the costars family.
Protein: MOT10_DANRE
Sequence: MTEPEPTLEQEPTPEPEPTQEPTPEPTPEPEPTQEPESEPELELKQENGCTKASEQKSPEEFEPPEGGWGWVVMLASMWCNGSVFGIQNAFGIMFVYLLNEFGSEHDADLRFKTAWVGSLSMGMIFFCSPIVSVFTDLLGCRITAVGGAAVGCVGLLASSFVTSLGPMYFTYGIVFACGCSFAYQPSLVILGHYFKRRLGLVNGIVTAGSSVFTITLPYMLSGLLKSVGLYHTLRVLAIFMFILMLAGLTYKPLLPKPVSSSKPGSRCPPLSRIFNVNIWKSLGYRIWAFGIPAALYGYFVPYVHLMTHVEERFGPEANKEVLLACIGITSGVGRLIFGRVADYVPGVNKVFLQVSSFMVIGVMSMMIPLCHVFGGLIAVCLLMGLFDGCFICIMAPIAFELVGSQNVSQAIGFLLGMMSIPMTVGPPIAGFLRDRLGSYDVAFYLAGIPPLIGGAVLCAIPWVEARRKRREAANTAENTEKMLESRSPPLEDTVCRTEEPESVI
What is the function of this protein?
Sodium- and proton-independent thyroid hormones and aromatic acids transporter.  Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) with high affinity, suggesting a role in the homeostasis of thyroid hormone levels (By similarity).  Responsible for low affinity bidirectional transport of the aromatic amino acids, such as phenylalanine, tyrosine, tryptophan and L-3,4-dihydroxyphenylalanine (L-dopa).  Plays an important role in homeostasis of aromatic amino acids (By similarity).
What are the official names of this protein?
Monocarboxylate transporter 10, MCT 10, Solute carrier family 16 member 10.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ADI1_USTMD
Sequence: MLHPIDTTIYRAGTSRGLYFLASDLPAEPSERDAALISIMGSGHPLQIDGMGGGNSLTSKVAIVSASTQRSEFDVDYLFCQVGITERFVDTAPNCGNLMSGVAAFAIERGLVQPHPSDTTCLVRIFNLNSRQASELVIPVYNGRVHYDDIDDMHMQRPSARVGLRFLDTVGSCTGKLLPTGNASDWIDGLKVSIIDSAVPVVFIRQHDVGITGSEAPATLNANTALLDRLERVRLEAGRRMGLGDVSGSVVPKLSLIGPGTETTTFTARYFTPKACHNAHAVTGAICTAGAAYIDGSVVCEILSSRASACSASQRRISIEHPSGVLEVGLVPPENAAQSLVDVAVVERSVALIAHARVYYTTPDRRRSYDSPLTSPSTPADTHNLFDAAYRPVIQPSDTDVEAPHMLALENKEQCVSRCDTALHHIVASYGASDAHASDRSLS
What is the function of this protein?
Aconitate-delta-isomerase; part of the gene cluster that mediates the biosynthesis of itaconic acid and 2-hydroxyparaconate (PubMed:26639528, PubMed:27750034).  Cis-aconitate is secreted by the mitochondrial tricarboxylate transporter MTT1.  In the cytosol cis-aconitate is converted into trans-aconitate via isomerization by the aconitate-delta-isomerase ADI1 (PubMed:26639528).  Decarboxylation of trans-aconitate by the trans-aconitate decarboxylase TAD1 then leads then to the production of itaconic acid (PubMed:26639528).  The cytochrome P450 monooxygenase CYP3 further converts itaconate to 2-hydroxyparaconate via oxidation of the double bond, leading to a transient epoxide, which can subsequently be lactonized to produce 2-hydroxyparaconate (PubMed:27750034).  Secretion of itaconate and possibly 2-hydroxyparaconate into the medium is mediated by the major facilitator ITP1 (PubMed:26639528, PubMed:27750034).  The glyoxalase domain-containing protein RDO1 is not involved in the biosynthesis of itaconate and 2-hydroxyparaconate, however, it might play a role in the further conversion of 2-hydroxyparaconate to itatartarate (PubMed:27750034).
What are the official names of this protein?
Aconitate-delta-isomerase 1, Itaconic acid/2-hydroxyparaconate biosynthesis cluster protein ADI1.
What is the protein family that this protein belongs to?
Belongs to the PrpF family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: PUR9_XANCP
Sequence: MASDFLPVRRALLSVSDKTGLIDLARALVARNVELLSTGGTAKAIRDAGLPVKDVAELTGFPEMMDGRVKTLHPLVHGGLLGRAGVDEAVMAEHGIAPIDLLVLNLYPFESVTAKADCTLADAVENIDIGGPAMLRSAAKNFARVAVATDPAQYADLLAELEANNGQLSAAQRFALSVAAFNRVAQYDAAISNYLSAVADSAESVPTRSPFPAQINSNFIKVMDLRYGENPHQSGAFYRDLYPVPGTLATFQQLQGKELSYNNLADADAAWECVRQFDAPACVIVKHANPCGVAVGVACGDAYELAYATDPTSAFGGILAFNRTLDAATAKAILDRQFVEVLIAPDYEPGALDYATKKANVRVLKIPHGAGLNNYDTKRIGSGLLMQSADNRGMSLGELSVVTKRAPSDAELADLLFAWRVAKYVKSNAIVYAKDSRTIGVGAGQMSRVVSAKIAALKAEEAKLTVAGSVMASDAFFPFRDGIDAAAAAGIQAVIQPGGSMRDGEVIAAADEHGLAMVFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: TSAD_NITOC
Sequence: MRVLGIETSCDETGVAVFDSKQGLLADILHSQAKLHAGYGGVVPELASRDHIRKLLPLLRKVLNQAGLNKEDIDGVAYTGGPGLIGALLVGAAVGRSLAWALGKPAIAVHHMEGHLLSPLLEPNPPGFPFCALLISGGHTMLVTVNRIGAYRILGESLDDAVGEAFDKTAKLLQLGYPGGPALAKLAEQGNPDRFYFPRPMLDRPGLNFSFSGLKTYALNTLHKNGSEAAADIARAFQDAVVDTLTVKCRRALQQTGLNRLVVAGGVSANQALRQRLKAMGTQENVQVYYPRLAFCTDNGAMIAFAGCQRLLAGEQTSSGFSVRARWPLDTLPEI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYZ2_MOUSE
Sequence: MKTLLTLGLLLLSVTAQAKVYERCEFARTLKRNGMAGYYGVSLADWVCLAQHESNYNTRATNYNRGDQSTDYGIFQINSRYWCNDGKTPRAVNACGINCSALLQDDITAAIQCAKRVVRDPQGIRAWVAWRAHCQNRDLSQYIRNCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.  Lyz2 is active against a range of Gram-positive and Gram-negative bacteria.  More effective than Lyz1 in killing Gram-negative bacteria.  Lyz1 and Lyz2 are equally effective in killing Gram-positive bacteria.
What are the official names of this protein?
Lysozyme C-2, 1,4-beta-N-acetylmuramidase C, Lysozyme C type M.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPF_SYNJA
Sequence: MPSRLSFHKYQGLGNDFILVDNRHQPQPCLTPEEAVALCNRRFGVGADGVIFLLPGQEGADFSMRLFNSDGSEAEMCGNGIRCLARFLQDLGIPGQDGAYQIHTLAGRIVPQVRPDGLVTVDMGIPRLLAGQIPTTLAKPEEKVVRQPLQVGGREWAVTAVSMGNPHCVVFLEEGGSLEELDLERVGPLFEHHPAFPERTNTEFAQVLGPNYLRLRVWERGAGVTLACGTGACAALVAAVLEERAEPQATVELPGGNLEIRWDPDTQHVWMTGPALPVFSGTTAE
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O51I1_HUMAN
Sequence: MLGLNGTPFQPATLQLTGIPGIQTGLTWVALIFCILYMISIVGNLSILTLVFWEPALHQPMYYFLSMLALNDLGVSFSTLPTVISTFCFNYNHVAFNACLVQMFFIHTFSFMESGILLAMSLDRFVAICYPLRYVTVLTHNRILAMGLGILTKSFTTLFPFPFVVKRLPFCKGNVLHHSYCLHPDLMKVACGDIHVNNIYGLLVIIFTYGMDSTFILLSYALILRAMLVIISQEQRLKALNTCMSHICAVLAFYVPIIAVSMIHRFWKSAPPVVHVMMSNVYLFVPPMLNPIIYSVKTKEIRKGILKFFHKSQA
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 51I1, Odorant receptor HOR5'beta11, Olfactory receptor OR11-39.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANR2_YEAST
Sequence: MNSGGEEPTIKPNVFNITQLLNSNGEKPGIACIFLSKFDMKKGNIIIWSKSINGAAIDLSNIEFKSLPAGIHEQTDDVVNFVVPKELDVCQTAKTTTYDYGIAYFKQNSFDIIENDNRIDRSKVQMFSLGVIIDVQNASSDSKKHFYKEIYHAYAANRYSSYLESLLGQWIRQRDLDKFDIFEKFFDENNQGHMAENSVEVFEHSPKERRHLVEYLPYWTRKLGPLIFPLWKASLLQSRILILVPQGESFELCNSLAYCVFLISMLPKNLIGNHVSDEYIKPIFTVSTSDIPFLESFKKGNGYVATTSEEILLYKPEIYDIVVKLTSSSTIEESPEKEVEILTASGEQNKATPLDLEVYEKLILGELQEDASTNATCRHHEVTEPISWLQFLIDGFFLLTTAGYLVAPYHLANNFKIPRHVSGPEPNNSEIQIAENLVRYFHRRTSNLYNDLKDVIQKSENIDSEQPITIAASFLTKLNLDCFSKQDHQFVKDIALKWFQRSIDISNLPECLGNLC
What is the function of this protein?
May be involved in lipid metabolism.
What are the official names of this protein?
Uncharacterized protein ANR2, AVL9-related family protein 2.
What are the subcellular locations of this protein?
Lipid droplet.
Protein: GLTP3_ARATH
Sequence: MKRKRCEMEETTKKKKMTEIGSAIEELSVLSIAKTTIVTTEKEAINIINLPLKPLLSFCNIIVQVLDKIGPTMAVLRHDIDQNIQRLEKMWESDPLVYSNLVEILRKEAKEGSSRKPKSCSRAALWLTRAMDFTLALLQRLVKDMSQNMEQAIEECYNLTIKPWHGWISSAAFKVALKLVPNNNTFINVLAAKDETHQMVQDDITSLISLLIPLLSQLHSILELYEVSKLKSP
What is the function of this protein?
May be involved in glycolipids transfer.
What are the official names of this protein?
Glycolipid transfer protein 3.
What is the protein family that this protein belongs to?
Belongs to the GLTP family.
Protein: FIP37_ARATH
Sequence: MEFSSQDDDFGGDDSAANATRASGNRRSFGDLEDDEDDIFGSTTVAPGVRTGMILSLRGSLKNCKDDLASCQNELESAKTEIQKWKSAFQNESFVPAGKSPEPRFLIDYIQNLKSSEKSLKEQLEIAKRKEASCIVQYAKREQEMAELKSAVRDLKSQLKPASMQARRLLLDPAIHEEFSRLKNLVEEKDKKIKELQDNIAAVTFTPQSKNGKMLMAKCRTLQEENEEIGHQAAEGKIHELAIKLAMQKSQNAELRSQFEGLYKHMEELTNDVERSNETVIILQEKLEEKEKEIERVKKGLEIVSELVGDKKDEVDEIDEDAKEEIAGGE
What is the function of this protein?
Probable regulatory subunit of the N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation at the 5'-[AG]GAC-3' consensus sites of some mRNAs (PubMed:15047892, PubMed:28503769).  Associates with MTA, MTB, VIR and HAKAI to form the m6A writer complex which is essential for adenosine methylation at specific mRNA sequences (PubMed:28503769).  N6-methyladenosine (m6A) plays a role in mRNA stability, processing, translation efficiency and editing (PubMed:15047892, PubMed:28503769).  Essential protein required during endosperm development and embryogenesis.  Involved in endoreduplication, especially in trichomes.  May play a role in splicing events (PubMed:15047892).
What are the official names of this protein?
FKBP12-interacting protein of 37 kDa, FIP-37, Immunophilin-interacting protein AtFIP37, Protein WTAP homolog.
What is the protein family that this protein belongs to?
Belongs to the fl(2)d family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Note=Nuclear with a speckled distribution pattern.
Protein: PANC_ALTMD
Sequence: MKVIDSISTLRQTVNAWRRNGESVGFVPTMGNLHDGHLKLVKKAKAHNDNVVVSIFVNPMQFGANEDLDAYPRTIEEDKAKLISVGADAVFLPSVAEMYPAGLDAQTFVEVPGISDSHCGASRPGHFRGVATVVTKLFNMVQPDDAFFGEKDFQQLQVIRALARDLSMAVTIHGVPTEREASGLAMSSRNGYLSKEEKATASAIYEEMQRVKAGIEGGNIDFSELEDAMVTNLEAKGFKKDYCQVVNASTFKAATANDKELVLLVAMFMGKTRLIDNLQITR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHAM_LISMO
Sequence: MEKRLLDFEVGETVDLFLLIKSSVKGTASNGKPFLSLVLQDKSGELEAKLWDVKESDEANYGVQQIVHLMGDIQNYRGRKQLKIRQIRQATALDGVSASEFMETAPINKEEMADEITQYIFEMKNANLQRITRALLKKYQDDFYDYPAAMRHHHEFVSGLSFHVVSMLRLAKSVADLYPSVNRDLLYAGVILHDLGKVIELSGPVSTTYTLEGNLIGHISIVVEEVSKIADELSIDGEEVVVLKHVLLSHHGKGEWGSPKPPLVREAEILHQIDLMDASLNMMDKVLKHTKPGEFSERVFGLDNRSFYNPTFE
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: SYN_CLOBH
Sequence: MDITLVKSLYRETEKHMDKEVKINGWVRTVRDSKNFAFVEVNDGSFFKNVQVILESSLENFKELCKMPISTSVEVEGIVQPTPNAKQPFEIKATRISIEGKSSTDYPLQKKRHTFEYLRTIAHLRPRSNAFSAVFRVRSLAAYAVHKFFQERGFVYTNTPIITGSDCEGAGEMFQLTTMDLNNIPKTEEGKIDFSKDFFGSPANLTVSGQLSAETFALAFRNVYTFGPTFRAENSNTARHASEFWMIEPEMAFAELTDYLDNAEDMVKFVINYVMENAPEEMAFFNSFVDKGLFDRLDNVVNSDFKRITYTEAVELLQKSGVKFDYEVEWGIDLQTEHERYLTEQIFKKPVFVTDYPKDIKAFYMRLNDDGKTVAAADLLVPGVGEIIGGSQREERLDVLEKRMEELNLNKEDYWWYLELRKYGETKHSGYGLGFERILMYITGMTNIRDVIPFPRTPGSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDH_STRMU
Sequence: MAEKVSFEEGKLQVPDKPVIPYIEGDGVGQDIWKNAQIVFDKAIAKVYGGHKQVIWREVLAGKKAYNETGNWLPNETLEIIKTHLLAIKGPLETPVGGGIRSLNVALRQELDLFACVRPVRYFKGVPSPLKHPEKTAITIFRENTEDIYAGIEWNAGTAEVQKVINFLQDDMQVKKIRFPKSSSIGIKPISIEGSQRLIRAAIEYALANNLTKVTLVHKGNIQKFTEGGFRKWGYELAKREYAAELASGQLVVDDIIADNFLQQILLKPERFDVVALTNLNGDYASDALAAQVGGIGISPGANINYQTGHAIFEATHGTAPDIAGQDLANPSSVLLSGCMLFDYIGWSKVSDLIMKAVEKAIANGQVTIDFAKELGVEALTTRQFSEVLLTYL
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: RL16_DINSH
Sequence: MLQPKRTKFRKQFKGRIRGEAKGGSDLNFGTYGLKALQPERITARQIEAARRAMTRHMKRQGRVWIRIFPDLPVTSKPVEVRMGKGKGSVDFWACKVKPGRIMFEIDGVSEPVAREALRLAAMKLPIKTRTVVREDW
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SMG_ECOLU
Sequence: MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNALLWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: NUON_ECOSE
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUD_ERYLH
Sequence: MEALSQIEGRAIPYGAKNVDTDVIVPAHWLKTITREGLGRGAFETLREVPDNIFDSEEFAGAPILIAGDNFGCGSSREHAAWALLDLGIRAVIAPSFSDIFSSNAFKNGIVTVVLSQYEVDRLMEVAQSDPIAVDLETQTVVTPFQDRFPFEIDPFRKHCLLNGLDEVGLTLTRDAAIADYESRQKTQTPWLTTGTERAA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SYDND_RUTMC
Sequence: MRTHFCGELNKDNIGQTVEIYGWVNRRRDHGGVIFLDMRDKHGIAQVVINPDNADFSLAETVRNEFVLKITGTIIARGEGLTNPKLSTGKIEIKAQNIEILNTSKPVPFQIDATDTSEEVRLRYRYLDLRSDTMQNRLRLRSRVTRYMREFMDEHDFLDIETPFLTKATPEGARDYLVPSRTHSGKFFALPQSPQLFKQLLMMSGFERYYQIVKCFRDEDLRADRQPEFTQLDVETSFMSENEIMTMMEKMTRGLFKLVINVDLGDNFPTITYADSMAKYGLDRPDMRISMQIVSIDKIMQGVDFKVFSGPANYDDSRVAALKVPNGASISRKNIDKYTKYVSIYGAKGLAYIKLNKNGPASPILKFLGDEVIAKVIEMTDAKTGDIIFFGADKSKIVNEALGNLREQLAKDLDLFDTQWAPIWVVDFPMFEVGDDGSLNTTHHPFTAPSVDAKTLEKTATTALSKAYDLVINGSEVGGGSIRIHQIDMQKTVLKLLGISDQEIQDKFGFFLNALEYGCPPHGGMAFGLDRLMMIMTGANSIRDVVAFPKTQTAACLLTDTPTSISRKLLRELSVKINLPEKD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAD2_SCHPO
Sequence: MLQARIEEKQKEYELICKLRDSSNDMVQQIETLAAKLETLTDGSEAVATVLNNWPSIFESIQIASQHSGALVRIPPSTSNTNASATEQGDVEEV
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  May be necessary for growth under high osmotic stress.
What are the official names of this protein?
DASH complex subunit dad2, High osmolarity sensitivity protein 2, Outer kinetochore protein dad2.
What is the protein family that this protein belongs to?
Belongs to the DASH complex DAD2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore. Kinetochore association occurs only during mitosis.
Protein: PNP_BRUSI
Sequence: MFNTHKVEIEWGGRPLTLETGKIARQADGAVLATYGETAVLATVVSAKEPKPGQDFFPLTVNYQEKTYAAGKIPGGYFKREGRPSENETLVSRLIDRPIRPLFVDGYKNDTQVVITVLQHDLENNPDILSMVAASAALTISGVPFMGPISGARVGYIDGEYVLNPNIDEMPESKLDLVVAGTSEAVLMVESEAQELPEDVMLGAVMFGHKSFQPVIDAIIKLAEVAAKEPRDFQPEDLSELEAKVLAVVENDLREAYKITEKQARYAAVDAAKAKAKEHFFPEGVEETEMSAEQFATIFKHLQAKIVRWNILDTGNRIDGRDLSTVRPIVSEVGILPRTHGSALFTRGETQAIVVATLGTGEDEQMIDALTGTYKESFMLHYNFPPYSVGETGRMGSPGRREIGHGKLAWRAIHPMLPAAEQFPYTIRAVSEITESNGSSSMATVCGTSLALMDAGVPIVRPVAGIAMGLIKEGERFAVLSDILGDEDHLGDMDFKVAGTEFGITSLQMDIKIDGITEEIMKVALEQAKGGRVHILGEMAKAISSSRAELGEFAPRIEVMNIPTDKIRDVIGSGGKVIREIVEKTGAKINIEDDGTVKIASSNGKEIEAAKKWIHSIVAEPEVGEIYEGTVVKTADFGAFVNFFGPRDGLVHISQLAADRVAKTTDVVKEGQKVWVKLMGFDERGKVRLSMKVVDQETGKEIVAEKKKEEVDAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.