PharMolix/UniProtQA huggingface dataset:
Protein: ARGP_AERSA
Sequence: MKALDYKLLLALDAVMQEQNFERAAQRLHITQSAISQRIKQLEQQFAEPLLIRSQPLQATPLGQKLLAHYRQVRQLELELAGEIAPDEPQAPIRVSIAVNADSLATWFLPALAPLLEQHPIELNLLVDDECRTLDRVREGQAFGAVSLHGQPLAGCCVDELGEMRYLLTASPAFVARHFPAGLTPAALAKTPAVAFDQRDDMHVSFMARHFGLEPGGYPCHTVRSSEAFVAMAEQGLAYCLIPELQIRQQLAQGILLDLSPSHHLIEPLYWHRWVLERGLHKQISQRLISEGRRALQPG
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: FMT_LACLA
Sequence: MTKTKIIFMGTPQFAATVLKGLIDSNQYEILAVVTQPDRKVGRKQELRMTPVKELALTVNLPVLQPEKLSGSVEMTQIMTLLESGEVGIVTAAFGQFLPGKLLDVAQFAVNTHASLLPKYRGGAPIHYAIMNGEKEAGVTIMEMIRKMDAGDMIAQDSTPILEDDNVGTMFEKLALVGRDLLLETLPKYLSGQLKAQAQNEDEVTFSPNISPEEEKIDWNKSAREIFNKVRGMNPFPVAHTTWNGERFKIYETKVVDDSVGNLQAGEIVEKTKKSLKVATGEGLLELLFVQPAGKPKMDIVSFLNGLGQKIQVGDKFGD
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: DEOC_BACAA
Sequence: MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCX4_CHLRE
Sequence: MGRGLSTKKFYFKIGVQLKSNWNPLIDKLISILKLNSFYSSFVLRLIKLCLTKYLLLYAQQH
What are the official names of this protein?
Uncharacterized 7.3 kDa protein in petA 5'region, ORF62.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ASSTI_METJA
Sequence: MRKRVYYWTDSEHINKPVISDTILNTGVKINILKAKVEPQEAFLILELFGSKETIEKALNYLSKFGEVEEISKVIKRDLEKCVHCGCCITQCPINVIYMDEDYNVVFKEEDCVGCKNCLKACPFKAIEIFE
What is the function of this protein?
Required for O-acetylhomoserine sulfhydrylase (OAHS)-independent homocysteine (Hcy) biosynthesis.  Together with MJ0100, catalyzes the condensation of sulfide with aspartate semialdehyde to generate homocysteine.  May be involved in the reduction of the disulfide formed in MJ0100.
What are the official names of this protein?
L-aspartate semialdehyde sulfurtransferase iron-sulfur subunit.
Protein: MCM10_DROME
Sequence: MGPAQKSGTDISIDDEEEILALEKLLGAAENENTKSAESEKAKPTAPILVPKLREDNSFANAFTFEKIVKPEKQKNAAIIKEPELDSSDDEEVKNFLERKYNEYGSDINKRLKQQQENAYESKVAREVDQELKKSIHVVTSTPQPLKNPHNPIKRQSAVSTTFQRPPPVAAAVASTSQSSAPVSAVFTDPVFGLRMINPLVSSSLLQERMTGRKPVPFSGVAYHIERGDLAKDWVIAGALVSKNPVKNTKKGDPYSTWKLSDLRGEVKTISLFLFKEAHKSLWKTAEGLCLAVLNPTIFERRAGSSDVACLSIDSSQKVMILGQSKDLGTCRATKKNGDKCTSVVNLTDCDYCIFHVKQEYGKMSRRSELQSATAGRGINELRNKVLGKNEVFYGGQTFTAVPARKSAKLITKERDRLSMLAGYDVSPFAHTANHTSKPKTAEPTKIPYAERGGPVSRLAGGVEASRKQRVQDLERLRLLKEENERFEKKKQAEGHVLGSDNKKESEAGTPAVSMPTTPVPDKFKNRGFSFDASLTPKLSGSENFSFEINVGSRQAQNAKLKAAALLKKKPLEKINPNSTRGSESGKRRAIDELNEKFSSSAKRQKIDEDDRELMRKSRIEKIMAATSSHTNLVEMREREAQEEYFNKLERKEAMEEKMLTTYKMPCKAVICQVCKYTAFSASDRCKEQKHPLKVVDAEKRFFQCKDCGNRTTTVFKLPKQSCKNCKGSRWQRTAMIREKKILTGRETLSVRGDEETFMGCLAGSANLNLLVPDEE
What is the function of this protein?
Proposed to be involved in DNA replication and to participate in the activation of the pre-replication complex (pre-RC).  May be involved in chromosome condensation.
What are the official names of this protein?
Protein MCM10 homolog, Sensitized chromosome inheritance modifier 19.
What is the protein family that this protein belongs to?
Belongs to the MCM10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEC_AZOSB
Sequence: MTDLPRAVVLLSGGLDSATCLAIARDMGLETYALSVAYGQRHAAELTASRRVAHALGAREHRVASVSLGEFGGSALTDPAIAVPEDAAPGGIPVTYVPARNTVMLSMALAWAEVLGARHIFVGVNAVDYSGYPDCRPAFIQAFETMANLATKAGVEGHPTTIHAPLIDLSKADIIRRGVALGVDYGLTVSCYQADDDGRACGRCDACRLRREGFAAAGIADPTRYQAR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: NDHI_ENYSE
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PRMA_DESHY
Sequence: MNWREIAVTVSSAGEEAVADLFYQLGCPGVSVEDPELLQSYVESGNWDYHDFGEIALTGTSVVKGYICEDHELQPKLRQLDEGLKELLQRFPEWVLQVKGLTVQEEDWATSWKAYFKPVRIGRHFLIKPSWEEVTPLPEDIILELDPGMAFGTGTHATTSLCLETLEETVKPDMRIFDLGTGSGILAIAAAKLGAQVEAIDLDSVAVKVAQENVELNQVADRISVRQGDLGTVLQGQADLVVANIIADVILMLIPDLKRIMKEDGEFLASGIIGHRSSDVEAGLGEHGLEVLEKKEDSGWVLLRARWQRASL
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_RHOPS
Sequence: MSGVNEIRSAFLNYFAKNGHDIVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGLEKRPYHRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKDRAIELAWNLITKEYGLPKDRLLVTVYSEDDEAFGLWKKIAGLPESKIIRIPTSDNFWQMGDTGPCGPCSEIFFDHGDHIFGGPPGSLEEDGDRFIEIWNLVFMQFEQVAPGNRTPLPKPSIDTGMGLERIAAVLQGKHDNYEIDLFQALIRAIAELTGADPQGEQKGSLRVIADHLRAASFLIADGVLPSNEGRGYVLRRIMRRAMRHGQLLGAREPLMWRLVWALVREMGQAYPELVRAEAMIEETLRLEETRFRKTLERGLTILDEKSGSLKKGDMFDGDTAFTLYDTYGFPLDLTQDALRNRGISVDIASFTDAMDRQRAKARASWAGSGEAATETVWFGLRDKLGATEFLGYDTETAEGVVTALVKDGKEVEALKAGDAGAIVLNQTPFYAESGGQVGDTGVLTGEGVRFRVTDTLKKAGDLFVHFGTVEEGTVKPEAALALEVDHSRRSSIRANHSATHLLHEALRQVLGDHIAQKGSMVAPDRLRFDFVHQKPITQDELRRVEDIANDIVLENDEVTTRLMAVDDAREAGARALFGEKYGDEVRVVSMGKASREHGSNAFGWSVELCGGTHVRRTGDIGLISVTGESAVASGVRRIEALTGRHARQSANAAMATAKAAAAELRTTLDDMPARIASLMDERKKLERELSDARKKLAMGGSGAAGAADGGADVRDVGGVKLLARAVEGIEIKDLKSLVDQGKKQLGSGVIALVAKSEDGKGSIVVGVTPDLVARFSAVDLVRKASEVLGGKGGGGKPDMAQAGGPDGSKAQAALDAIAAAIGG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTFP1_MOUSE
Sequence: MSEQQRQGAERDLYRDTWVRYLGYANEVGEAFRSLVPAAVVWLSYGVSSSYVLADAIDKGKKAGEVPSPEAGRNTRMALAVVDTFVWQSLASVAIPGFTINRLCAASLYVLGTMTHWPPTVRKWTTTTLGLLAIPVIIHPIDRSVDFLLDSSLRKLYPSVEKPSTP
What is the function of this protein?
Involved in the mitochondrial division probably by regulating membrane fission.  Loss-of-function leads to apoptosis (By similarity).
What are the official names of this protein?
Mitochondrial fission process protein 1, Mitochondrial 18 kDa protein, MTP18.
What is the protein family that this protein belongs to?
Belongs to the MTFP1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NQOR_BRUSU
Sequence: MVKMLVLYYSAYGHMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQYGGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGMTTTADGDGSRQPSAQELDGARFQGRRVAEITAKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: RPIA_CHRVO
Sequence: MLTQDQLKLAVAKKALEFVPEDAIIGVGTGSTVNLFIEELAGIKGRIKGAVSSSEASTARLKAHHIQVFDLNEVEKLSVYIDGADEINHHLHMIKGGGAALTREKIVAGVADEFICIADEKKYVTMLGAFPLPIEVIPMARSYVARELVKLGGHPELRQGVTTDNGNVILDVHGLQIMKPVELEETINHIAGVVTCGLFARRRADVLLLGKQDGVEVLR
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: FKBP3_HUMAN
Sequence: MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
What is the function of this protein?
FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways.  PPIases accelerate the folding of proteins.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP3, PPIase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-25, FK506-binding protein 3, FKBP-3, Immunophilin FKBP25, Rapamycin-selective 25 kDa immunophilin, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CH10_STRE4
Sequence: MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSETGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_RICBR
Sequence: MQKLIIHGGKPLKGIINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKELLKSHGAGIEIIEHENEFELVINAANINNLTADYEIVRKMRASIWVLGPLLSRYGKAKVSLPGGCAIGARQVDLHIAVLKAMGAEITIEDGYINASTAGRLKGTHFIFDKISVGATINAVLAAVLADGETLLFNCAREPEIVDLCNCLNKMGADISGIGTSEIRINGKDSLSEASYRVLPDRIEAGTYMFAAAITKGDLKLYGIDYHIIENIALKLIETGIKVMPIDNGVQVTYADKLNAVNLETNPYPGFATDLQAQFMSLMTISQGSSIITENIFENRFMHVPELCRMGADITVRGNQAIVQGVKGLKGAEVMASDLRASVSLILAGLSTDSETVLHRIYHLDRGFQNLEKKLNNCGADIKRV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEA_PHOLL
Sequence: MNDNIARKMQQTYNIAYWGGSYYYVNDLGNVSVCPNPDLPGAKIDLAELVKRVQQEQKHLRLPALFCFPQILQHRLRSINAAFKRARESYGYKGDYFLVYPIKVNQQRRVIESLASSGEPLGLEAGSKAELMAVLAHAGMTRTVIVCNGYKDREYIRLALIGEKLGHKVYLVIEKMSEIAQVLEEAERLNVIPRLGVRARLASQGSGKWQASGGEKSKFGLAATQVLQLVETLRAVDRLDSLQLLHFHLGSQLANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNVIWGIGDACDEHGLPHPTVITESGRALTAHHTVLVSNVIGVERNEFTQTTPPAEDASRPLTSLWETWQEMHSEGNRRSLRESLHDGQLDLHDVHTQYAHGMLDLTERAWAEELYLNICRRIQQDLDPSNRAHRPIIDELQERMADKFYVNFSLFQSLPDAWGIDQLFPVLPIEGLDKPLDRRAVLLDITCDSDGIVDHYVDGDGVAATMPMPAYDPDCPPMIGFFMVGAYQEILGNMHNLFGDTAAIDVYVFDNGEVTYNQSEEGDSVADMLQYVKLDPNVLMARFRDQVKGADLDTGLQEQFLLEFESGLYGYTYLEDE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: GFOD2_XENLA
Sequence: MMTLPGIGVFGTGNTARVLIQLLRAEGFSIEALWGKTDEDAKVVAEEMGIPFYTSHTDDVLLHQEVDLVCISIPPPLTRQIAVKALGIGKNVICEKAASSLDAFTMVKAARYYPKLMSLVGNALRFLPAFDRMRQLILEQGYVGEIRICDVRVYGGSLLSSNYSWICDDLMGGGGLHTLGTYLVDLLTHLTNKKAEKVHGFLKTFVKQNEAISGIRYVTSDDFCFFQMQMTGGACSTVTLNFNMPGTFVHEVMVVGSAGRLVVRGTELYGQKNSASEEKLLLSEPLTSDIADVSDFDKVPPPYLMGIAHMVKALRQSFQDQEDRRTWDHKPLSVAATFEDGLYMQRVVDAIKRSNRSGEWESVELTNEETDSNQNLSEVIQHNL
What is the function of this protein?
Promotes matrix assembly.
What are the official names of this protein?
Glucose-fructose oxidoreductase domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HID1_DICDI
Sequence: MGTGSSREQHLNSFNTLQKETVPFSSDLWKTILSQNLEDDSLYLENLKKLKNERPENLATFIKKLVNQLVLVKGLQRETNTPGDFQLTSISLSYLSRILPIVFESGDDFADKVFWLNEGIEPLSHPSAKISTPPSITTTKTTEIIEEQEKKDQENKQVEENKENEEKKDEEKKDEEKKDEEKKDEDKKENKTTTTTTTTNTTNNTNNNNNSDESSFDTTPLAVKLMDSLLDLLFFPGFTVTESLGLKSPKEASPDAIPVLFSWAGGFGVDSVPTVHNKQFWINRLSVLQCLITCLSEQLYVPQDSVSTFKSKWLDWITHTQEYYTEALLFSLINTFATFDPIGWGIPYNHLMYSDDHEICSKLSIQILNVLLTYDPIENNDQQPQQQHHHHQQQHHQQQQQQQQSTIECRNKFIQYIKTLKRVRDFKFFFNAFERIMNVPLIASHTKLPNSTKKIELHQDLTYTMWLFLSYNHDFLRSIVNYENSPEFLIPLLQYMDEGRKSQTTHGIVQIGTFILLLLSGERDFSISLNKPFVGRIHIDIQQPQVYSDFVITVMYRLLVDTPDRLESIYECVLTILSNLSPYMKNLSMVTCVKLMKLFEYLSTPRFLFATNHNYRYVGFLLESLNNLLQHQYESNTRLIYAILRCQNQFSKLAYLKISPVTPSKPMEQITQPSPISTSEEAFGKLNKLSISEEPSTLSNEKSDKTTDGGDHQDESISKSKVQSKPTTEHPNSTGATPSSTNSGTPTIKAFSSTTPNQESPKLGGDGIDSQSSTPNKQQLPPPPPQQTKKTQMVSHFMPTDEWLQDIKKQLPLDNILKVITHLSPQIQGLCTGSGSDEQKIMDYLKMSTIVGIFHNPGPIMTRRYHSNAITKSWFIAYMWCIIYLENHSPPLFLHTNIKLFQVKQ
What are the official names of this protein?
Protein HID1, HID1 domain-containing protein, Protein hid-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the hid-1 family.
Protein: PDXH_NITWN
Sequence: MNDTTDIKHTSQLTSGDFTEAREPFALFEAWLAEATASEPNDPDAMALATADADGLPDLRMVLMKGFDARGFVFYSHIASAKGRELAANPKAALLFHWKSLRRQVRVRGPVTPVTDAEADAYFATRPRQAQIGAWASRQSRPLESRLAFEQAIAKEAAKYAIGAVPRPPGWSGWRITPLQFEFWHDRPFRLHDRIEFRRSALDVPWTKTRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: END8_PECCP
Sequence: MPEGPEIRRAADKLVEAVVGKTLTRVWFAFPELKPYEAELVGQQVRQIATRGKALLTYFSNDRVLYSHNQLYGVWRVVNAGESPETKRDLRVRLETQNRAILLYSASDIEMLTPEALTTHPFLQRIGPDVLDLSLTPEQVYERLLLPRFRRRQFSGLLLDQAFLAGLGNYLRVEILWQAQLAPQHTAAQLNEEQLQTLSQALLEIPRLSYNTRGTVDENHHHGAIFSFKVFHRDGESCERCGGIIERTMLSSRPFYWCPHCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: HSLO_PROMT
Sequence: MTDSLVRATAAKGGIRLVAVSTTESTKEAKERHSLSYLTSAIVGRAMSASLLLASSMKVNHGRVTLRISSNGPLKGLTIDAGRDGSVRGYVGDPSLELDLIKNKSNHYTFDFKKATGIGYLHVIRDDGKGEPHNSTVELINGGIGEDIASYLLHSEQTPSAVFVGEKINQDGIVCSGGLLAQILPKAERDYSLIDLLEDRCKEINSFSELLNKKGNNLISLIEEIFPDLDQSPSDIISTSQEVHFKCRCSRERSLSALKILGKDELQKMIKEDGKAELTCQFCKNVYLVKEDELISLID
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_MYCPA
Sequence: MKQSLAVKTFEDLFAELGERARTRPAGSATVAALDGGVHGLGKKILEEAGEVWLAAEHESDDALAGEISQLLYWTQVLMTARGLSLDDVYRKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIB2_SHEEP
Sequence: LFYRYQDCTFFNKKDILKLHARFYELAPNLVPMDYRKSPIVHVPMSLIIQMPELRENPFKERIVEAFSEDGEGNLTFNDFVDMFSVLCESAPRDLKASYAFKIYDFNTDNFICKEDLQLTLARLTKSELDEDEVVLVCDKVIEEADLDGDGKLGFADFEDMIAKAPDFLSTFHIRI
What is the function of this protein?
Calcium- and integrin-binding protein that plays a role in intracellular calcium homeostasis (By similarity).  Acts as a auxiliary subunit of the sensory mechanoelectrical transduction (MET) channel in hair cells (By similarity).  Essential for mechanoelectrical transduction (MET) currents in auditory hair cells and thereby required for hearing (By similarity).  Regulates the function of hair cell mechanotransduction by controlling the distribution of transmembrane channel-like proteins TMC1 and TMC2, and by regulating the function of the MET channels in hair cells (By similarity).  Required for the maintenance of auditory hair cell stereocilia bundle morphology and function and for hair-cell survival in the cochlea (By similarity).  Critical for proper photoreceptor cell maintenance and function (By similarity).  Plays a role in intracellular calcium homeostasis by decreasing ATP-induced calcium release (By similarity).
What are the official names of this protein?
Calcium and integrin-binding family member 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, stereocilium. Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Cell membrane, sarcolemma. Note=Colocalized with ITGA7 at the myotendinous junctions (MTJ) and at the neuromuscular junctions (NMJ). Localizes in the cuticular plate along and at the tip of the stereocilia of vestibular sensory hair cells.
Protein: KDSA_ENT38
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSINSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQAQPVAEVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFIEGGNDQIILCDRGANFGYDNLVVDMLGFSVMKKVSNNSPVIFDVTHALQCRDPFGAASSGRRGQVTELARAGMATGIAGLFIEAHPDPANAKCDGPSALPLDKLEPFLKQIKAIDDLVKSFDELDTSN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX1_CHORO
Sequence: PEVYILILPGFGMISHIISQESGKKETFGCLGMIYAMMAIGLLGFVVWAHHMFTVGMDIDTRAYFTSATMIIAVPTGIKIFSWLATLHGTQINYSPSMLWSLGFVFLFTVGGLTGVILANSSIDVTLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWYPLFTGLAMNPYLLKIQFFTMFIGVNLTFFPQHFLGLAGMPRRYSDYPDIYTSWNIISSLGSYISLIATMLMLMIIWESLINKRIILFPLNMNSSIEWYQNLPPAEHSYNELPILSNF
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPOY_LISMF
Sequence: MIFKVFYQETLTETPVREKTQSLYVEAESEVKVRQLLKDEPFHIEFVEKISDAHLAYEKENPDFALWEK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: RS2_METBU
Sequence: MENTDQNIEITAETSAAAENTESTSLVPIDEYLAAGVHIGTQQKTQNMMKFVYRVRTDGLYVLDIQSTDERIRSIAHFLSMYDPSRILVVSARQYGQYPATMFSKSVGAVSKVGRFIPGSLTNPVQEGFFEPDVVIVTDPAGDAQVIREAVNVGIPVVALCDTNNMTSNVDLVIPTNNKGRKALSLVYWLLAREIANERDIPFNYEASEFETGL
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MTGA_AGRFC
Sequence: MDFRTLAKRIIMTLLALLILPYLLIPVYALPFIRPVSTLMLADLVTLQGYDRRWVPLEDISPRLVQSVMMSEDGQFCFHGGVDWNQMQSVVSNALDGASTRGASTIPMQTAKNLFLWNGRSFLRKGLELPLAIAADFVWSKKRMMEIYLNVAEWGPGIYGIEAAAQHHFKIPAAKLSSRQAALLAVSLPNPIDRVASKPGRGLQRLAGLIERRARASGGYVGCVLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.