PharMolix/UniProtQA huggingface dataset:
Protein: SYP_ECO8A
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYLVKQIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSDM_GILLR
Sequence: MSKVLKNALAGYGYNLVALPKEGIAPLLLLYKNKRDVSSSGNNIDKLFALADSPPPIVSKNNATLNLQQNSTVSFDGKAGVDILDWLLQKLKMGKLRGNINADHINSLQISYQNVFEDNVSLLQLDNFISGSEPKVDQFNTFKEKLKDNELFVINSVLKSNSFSVSAQNKNGQNIDLEATIKGIVDADVNVGRSKKDEVLMEYKNATPIVFAFKAQKIIYDHKKWWQFFKKGDAKFRIKDEHGVVLKDESGFPTQSLEETNELINI
What is the function of this protein?
Pore-forming protein that causes membrane permeabilization via a pyroptosis-like activity.  Makes ring-like pores when released.
What are the official names of this protein?
Gasdermin bGSDM, bGSDM, Bacterial gasdermin.
What is the protein family that this protein belongs to?
Belongs to the bacterial gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin bGSDM]: Cytoplasm. SUBCELLULAR LOCATION: [Gasdermin bGSDM, N-terminus]: Cell inner membrane; Multi-pass membrane protein.
Protein: LSRB_SHIFL
Sequence: MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTSGGNGAQQAGKELSVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPALKRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYSSPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAIIAPDANALPAAAQAAENLKNDKVAIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISVYVADVLLKKGSMKTGDKLDIQGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKENIGKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL17_EHRRG
Sequence: MRHRVAHRKFSRTSAHRISMLLNLSISLIKHERITTTLPKAKELRPYVEKLITIGKVYREKNLVYGKRLLISKLKNIDATDKLIDVLSVRYKSRNGGYTRIMKNGFRKGDCAPIAIIELVDRQIVSQS
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HIS7_MYCBT
Sequence: MTTTQTAKASRRARIERRTRESDIVIELDLDGTGQVAVDTGVPFYDHMLTALGSHASFDLTVRATGDVEIEAHHTIEDTAIALGTALGQALGDKRGIRRFGDAFIPMDETLAHAAVDLSGRPYCVHTGEPDHLQHTTIAGSSVPYHTVINRHVFESLAANARIALHVRVLYGRDPHHITEAQYKAVARALRQAVEPDPRVSGVPSTKGAL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPGP_ECO57
Sequence: MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLREANVPVILCSSKTSAEMLYLQKMLGLQGLPLIAENGAVIQLAEQWQEIDGFPRIISGISHGEISQVLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQFTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPNDAPLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KA132_ORTSC
Sequence: ACGPGCSGSCRQKGDRIKCINGSCHCYP
What is the function of this protein?
Potent and selective inhibitor of Kv1. 2/KCNA2 potassium channels.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 13.2, OsK-2, OsK2.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 13 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: VFLIP_HHV8P
Sequence: MATYEVLCEVARKLGTDDREVVLFLLNVFIPQPTLAQLIGALRALKEEGRLTFPLLAECLFRAGRRDLLRDLLHLDPRFLERHLAGTMSYFSPYQLTVLHVDGELCARDIRSLIFLSKDTIGSRSTPQTFLHWVYCMENLDLLGPTDVDALMSMLRSLSRVDLQRQVQTLMGLHLSGPSHSQHYRHTP
What is the function of this protein?
Plays a role in the modulation of host signaling pathways by acting as an activator of both the classic and the alternative NF-kappa-B pathways.  Thereby, initiates an important range of cellular processes to promote cell survival, proliferation and protection from apoptosis.
What are the official names of this protein?
Viral FLICE protein, vFLIP.
Protein: HBA1_TRICR
Sequence: MKLSADDKHNVKAIWEHVKGHEEAIGAEALCRMFTSLPTTRTYFPTKDIKEGSSFLHSHGKKVMGALSNAVAHIDDIDGALSKLSDKHAEELMVDPANFPKLAHNILVVLGIHLKPHLTYSVHSSVDKFLATVGYVLASKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-1, Alpha-1-globin, Hemoglobin alpha-1 chain, Hemoglobin alpha-major chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CYB_MICMC
Sequence: MTIMRKSHPLMKMVNHAFIDLPAPSNISGWWNFGSLLGLCLIIQIVSGLFLAMHYTPDTLTAFSSVTHICRDVNYGWLIRNMHANGASLFFICLYLHIGRGIYYGSYTYMETWNSGIILLFLTMATGFMGKVFPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLNRFFAFHFILPFIIAAMAMVHLLFLHETGSNNPLGIPSDCDKIPFHPYYTTKDFLGMVLLLAFFFTMVLISPDLLGDLDNYSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALVLSILVLALFPHIQTANQRSLMFRPISQFLLWMMVSDVLILTWIGGQPVEPPFIIIGQVASLLYFLIILALMPIAGLNENKMIKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SCX9_CENEX
Sequence: KDGYPVEVTGCKKSCYKLGENKFCNRECKMKHRGGSYGYCYFFGCYCEGLAESTPTWPLPNKSCGKK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Neurotoxin Cex9.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EBPR_ANOGA
Sequence: MALGNALYPLTATVFLCVVGFATSSNENSRFLINSRLEVNVKSLLGEICGTNSSLLSIGVKSLSNEYSDRTVENLCGNETTEVLLWIPVGNFGNLAELGLSSRYLGKGAGDEDFAEYCSYDVTTKSCTTDNGAVEGSILLLAEKFPERYELRDLVYKKWRNSTHLGAPILAYGTLKNREPAYKYVDQDISYLADTRIEYVLPATVTHGIPLSVYRGKTESYKLVAGETYYSRIFKTINAIRYMSPYSTINVTVIGSEGRDYREFRAKLVTVYTDEEGYGWSKSLSSIEAAMIETKLTETHVEYALPVNLYDTQPPVLSPLLPALNEGNSIVDKGQQPAKGIVAKPENIHIHISELDFGQAYPGFRNVAIGAAILFFSVLGVAIIDMIRRTIANRRAKRLHLGKYSRT
What is the function of this protein?
(Microbial infection) Acts as a receptor for ENO/enolase from parasites P. berghei and P. falciparum (PubMed:24474798).  The interaction is involved in the invasion of the mosquito midgut by P. berghei ookinete, but is dispensable for P. falciparum ookinete invasion (PubMed:24474798).
What are the official names of this protein?
Enolase-binding protein, AgEBP.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Localizes to the luminal side of the midgut epithelium.
Protein: DLGP4_RAT
Sequence: MKGLGDSRPRHLSDSLDPPHEPLFAGPDRNPYLLSPTEAFAREARFPGQNTLPGDGLFPLNNQLPPPSSTFPRIHYNSHFEVPEESPFPSHAQATKINRLPANLLDQFEKQLPIHRDGFSTLQFPRGEAKARGESPGRIRHLVHSVQRLFFTKAPSMEGTTGKVGGNGGKKGVLEDGKGRRAKSKERAKAGEPKRRSRSNISGWWSSDDNLDGEGGAFRSGPASGLMTLGRQPERTQPRYFMHAYNTISGHMLKTTKNTTTELTAPPPPPAPPATCPSLGVGTDTNYVKRGSWSTLTLSHAHEVCQKTSATLDKSLLKSKSCHQGLAYHYLQVPGGGGEWSTTLLSPRDMDSTAEGPIPCRRMRSGSYIKAMGDEDSDESGGGSPKPSPKTAARRQSYLRATQQSLGEQSNPRRSLDRLDSVDMPLPSKYPSWEEDYNPISDSLNDSGCISQVFGQASLIPQLFGHDQQVREADLSDQYEAACESACSEAESTAAEALDLSLPSYFRSRSHSYLRAIQAGCSQEEDSVSLQSLSPPPSTGSLSNSRTLPSSSCLVAYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSSTRPPSVTRGGITPGPEAPEPPPKHAALKSEHGTLTSSESHSEAVPKRKLSSIGIQVDCIQPVPKEEPSPATKFQSIGVQVEDDWRSSAPSHSMSSRRDTDSDTQDANDSSCKSSERSLPDCTSHPNSISIDAGPRQAPKIAQIKRNLSYGDNSDPALEASSLPPPDPWMETSSSSPAEPAQPGACRRDGYWFLKLLQAETERLEGWCCQMDKETKENNLSEEVLGKVLSAVGSAQLLMSQKFQQFRGICEQNLNPDANPRPTAQDLAGFWDLLQLSIEDISMKFDELYHLKANSWQLVETPEKRKEEKKPPPPVPKKPAKSKAAVSRDKASDAGDKQRQEARKRLLAAKRAASVRQNSATESADSIEIYVPEAQTRL
What is the function of this protein?
May play a role in the molecular organization of synapses and neuronal cell signaling.  Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton.  May induce enrichment of PSD-95/SAP90 at the plasma membrane.
What are the official names of this protein?
Disks large-associated protein 4, DAP-4, PSD-95/SAP90-binding protein 4, SAP90/PSD-95-associated protein 4, SAPAP-4.
What is the protein family that this protein belongs to?
Belongs to the SAPAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: GUAA_MESFL
Sequence: MKNTQILILDFGSQYTQLLARRVREANIYTEVLPFDTSIEKIKEYPLLKGIILSGGPSSVYLQNAYKIDSEILNLDIAILGVCYGMQLLTQYFQGAVELADEQEFGKAIITIDDKKNPLFKNVTTESQVWMSHADHVTELPVDFKQIAHSNASIAAIAHNTKPIYGIQFHAEVTHSLQGKEMLENFLYDIAKCNKDWNLDDFIDQQIKEIKETVKDKQVILGLSGGVDSSVAAAIIGKAIGKQLTCIFVDTGLLRKNETIEVMKAYETNFDINIKLVEASDLFFSELKGIKEPEAKRKIIGKCFIDVFTDAARQHKDADFLAQGTIYPDVIESSSHGASSKTIKSHHNVGGLPEDLKFRLIEPLRNLFKDEVRQVGFKLGLPEEMINRHPFPGPGLGIRVIEEVTKDKVEILQEADAIFIKKLREWNLYNTVSQAFVTLLPVKTVGVMGDNRTYDYVVALRSVNTIDFMTATSTHLPWEFLDEVVNEIINKVDNVNRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MTNX_BACCQ
Sequence: MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEVKNRILSQELSIQEGVSQLFQFIPTNLHDEIIQFLIETAEIRNGFHEFIQFVNENNISFYVISGGMDFFVYPLLQGLIPKEQIYCNETDFSNEYITVNWPHPCDRLCQNHCGLCKSSLIRKLSDTNDFHIVIGDSITDLQAAKQADKVFARDFLITKCEENHISYTAFETFHDVQTELKHLLEVKL
What is the function of this protein?
Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase, HK-MTPenyl-1-P phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MtnX family.
Protein: GR02A_DROME
Sequence: MDTLRALEPLHRACQVCNLWPWRLAPPPDSEGILLRRSRWLELYGWTVLIAATSFTVYGLFQESSVEEKQDSESTISSIGHTVDFIQLVGMRVAHLAALLEALWQRQAQRGFFAELGEIDRLLSKALRVDVEAMRINMRRQTSRRAVWILWGYAVSQLLILGAKLLSRGDRFPIYWISYLLPLLVCGLRYFQIFNATQLVRQRLDVLLVALQQLQLHQKGPAVDTVLEEQEDLEEAAMDRLIAVRLVYQRVWALVALLNRCYGLSMLMQVGNDFLAITSNCYWMFLNFRQSAASPFDILQIVASGVWSAPHLGNVLVLSLLCDRTAQCASRLALCLHQVSVDLRNESHNALVGTLVRYCAPLIILVPLQITQFSLQLLHQRLHFSAAGFFNVDCTLLYTIVGATTTYLIILIQFHMSESTIGSDSNGQ
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its not yet determined substrates.
What are the official names of this protein?
Putative gustatory receptor 2a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURL_BARBK
Sequence: MSVRNNSAITPELIAHHGLKIDEYQRILELIGREPTFTELGIFSAMWNEHCSYKSSKKWLKTLPTKGKCVIQGPGENAGVVDIGNGQCVVFKMESHNHPSYIEPYQGAATGIGGILRDIFTMGARPVAAINALRFGSPDHPRTRHLVSGVVSGIGGYSNAFGVPTVGGEVNFDKRYNGNILVNAFAAGIAKIDSIFYSKAQGVGLPVVYLGAKTGRDGVGGATMASAEFDDAIDEKRPTVQVGDPFTEKCLLEACLELMALKAVIAIQDMGAAGLTSSSVEMGAKGNLGIELNLDKIPVREENMTAYEIMLSESQERMLMVLKPEMEKQAAAIFHKWGLDFSIIGKTTDDLRFRVLHQGKEVVNLPIKELGDEAPVYDRPWIAPSPKAILKAEEVKEIENFGDALLTLLNSADQSSRRWVYEQYDTFIQGNSLVRPGGDAGVIRVDNNDKHALAFSSDVTPRYCEADPYEGGKQAVAECWRNISATGATPLAATDNLNFGNPEKPEIMGQLVFAIKGIGEACKELDFPIVSGNVSLYNETNGESILPTPTIAGVGIIDDWLKVVTVGGMQDGDIIILVGPCGSHLGQSIYVRDILNIDTGTPPHVDLQLEKKNGQFVRDVINRGFIHAAHDISDGGLAIALAEMVIKSGKGIRAKLSNISPRHAELFGEDQGRYLIAIKPNALNSLKELSQTNMISLTELGTVEGDALDIKDTLSLSVSQLTQAYESWFPKFMGNST
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGJ_PROMM
Sequence: MALVEDVFSLSPKAVSSALASLWRPIQGGVSAPLGFQAAGITAGLKDSGKPDLALLLAPEGAVCAGMFTTSLVRAACVDLCVDHLQACGGKARAVLINSGQANACTGERGWLDSLRASQALAGRLELPVEQVLICSTGVIGVPIPMDTLLAGLDPLVEALSDEGGAEAAGAILTTDLVEKQFALEAELGGRSVRIGGMAKGSGMIHPDMATMLGYLSCDVGVEVDAWQAMLKRVVDCSFNAMTVDGDTSTNDSCLAFAAGELLEQEHLQALEAGLLVAAQQLAKAIARDGEGATCLLEVQVEGVVGDVEARRIARTVCGSSLVKTAVHGRDPNWGRIVAAAGCAGVPFDPAAVALWLGPHQLMEFGEPLPFDRLAASRYMQERVDGSYLCDDTVQIRLVVGDGSGDGMAWGCDLSDQYVRINADYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_STRPJ
Sequence: MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAGKGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSKRFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINELLKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLGELTDVYEIVWEKLQGLK
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CNKR3_HUMAN
Sequence: MEPVTKWSPKQVVDWTRGLDDCLQQYVHKFEREKINGEQLLQISHQDLEELGVTRIGHQELVLEAVDLLCALNYGLETDNMKNLVLKLRASSHNLQNYISSRRKSPAYDGNTSRKAPNEFLTSVVELIGAAKALLAWLDRAPFTGITDFSVTKNKIIQLCLDLTTTVQKDCFVAEMEDKVLTVVKVLNGICDKTIRSTTDPVMSQCACLEEVHLPNIKPGEGLGMYIKSTYDGLHVITGTTENSPADRSQKIHAGDEVIQVNQQTVVGWQLKNLVKKLRENPTGVVLLLKKRPTGSFNFTPAPLKNLRWKPPLVQTSPPPATTQSPESTMDTSLKKEKSAILDLYIPPPPAVPYSPRDENGSFVYGGSSKCKQPLPGPKGSESPNSFLDQESRRRRFTIADSDQLPGYSVETNILPTKMREKTPSYGKPRPLSMPADGNWMGIVDPFARPRGHGRKGEDALCRYFSNERIPPIIEESSSPPYRFSRPTTERHLVRGADYIRGSRCYINSDLHSSATIPFQEEGTKKKSGSSATKSSSTEPSLLVSWFTRLKLLTH
What is the function of this protein?
Involved in transepithelial sodium transport.  Regulates aldosterone-induced and epithelial sodium channel (ENaC)-mediated sodium transport through regulation of ENaC cell surface expression.  Acts as a scaffold protein coordinating the assembly of an ENaC-regulatory complex (ERC).
What are the official names of this protein?
Connector enhancer of kinase suppressor of ras 3, Connector enhancer of KSR 3, CNK homolog protein 3, CNK3, CNKSR family member 3, Maguin-like protein.
What is the protein family that this protein belongs to?
Belongs to the CNKSR family.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane; Peripheral membrane protein.
Protein: SAHH_AROAE
Sequence: MNSVAENFTDYVVADLALAGWGRKEIRIAETEMPGLMAIREEFAVVQPLKGARITGSLHMTIQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAIAASGVPVFAVKGESLADYWDYTHRIFEWRDGGYSNMILDDGGDATLLLHLGARAEKDVSVLAKPGSEEERVLFAAIRAKLASDPTWYSVRLAAIRGVTEETTTGVHRLYQMFERGELKFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMVAGKVAVVCGYGDVGKGSAQALRALSAQVWVTEIDPICALQAAMEGYRVVTMDYAAEHADIFVTCTGNYHVIRHDHMARMKDQAIVCNIGHFDNEIDVASIEGYEWEEIKPQVDHVIFPDGKRIILLAKGRLVNLGCATGHPSYVMSSSFANQTIAQIELFTRTADYPVGVYTLPKHLDEKVARLQLKKLNAQLTELRPDQAAYIGVPVEGPYKSAHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BARH2_MOUSE
Sequence: MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHSQQPPPPSAVPAQSLQPSPQQQPPPQPQSAAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAAHESFRPKLEQEDGKTKLDKREDPQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSNPIPGTPHPR
What is the function of this protein?
Potential regulator of neural basic helix-loop-helix genes.  It may down-regulate expression of ASCL1 and, within the thalamus, up-regulate NGN2, thereby regulating distinct patterns of neuronal differentiation (By similarity).
What are the official names of this protein?
BarH-like 2 homeobox protein, Bar-class homeodomain protein MBH1, Homeobox protein B-H1.
What is the protein family that this protein belongs to?
Belongs to the BAR homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA84_METTH
Sequence: MYIIFRCDCGRALYSREGAKTRKCVCGRTVNVKDRRIFGRADDFEEASELVRKLQEEKYGSCHFTNPSKRE
What are the official names of this protein?
Protein MTH_1184.
Protein: Y1264_LACDB
Sequence: MTEADQVRKRINELYKKKQESGLTEVEEAERKELHKQFIANFRAGFKQQLDSLVIVDDQGKDVTPDKAKQIQKKKVLR
What are the official names of this protein?
UPF0291 protein LBUL_1264.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SR542_SOLLC
Sequence: MVLAELGGSISRALQQMSNATIIDEKVLNECLNEITRALLQADVQFKLVRDMTTNIKKIVNLDDLAAGHNKRRIIQQAVFNELCKILDPGKPSFTPKKGKPSIVMFVGLQGSGKTTTCTKYAYYHQKKGWKPALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVDGVETFKKENCDLIIVDTSGRHKQEAALFEEMRQVAEATKPDLVIFVMDSSIGQAAFDQAQAFKQSVAVGAVIVTKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGMGDWSGFMDKIHEVVPMDQQPELLQKLSEGHFTLRIMYEQFQNILKMGPIGQVFSMLPGFSAELMPKGRENESQAKIKRYMTMMDSMTNEELDSSNPKLMTDSRIMRIARGSGRQVHEVMDMMEEYKRLAKIWSKMKGLKIPKKGEMSALSRNMNAQHMSKVLPPQMLKQIGGMGGLQNLMKQMGSAKDMMGGMGGMFGGGDK
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).  As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane.  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA.  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA.  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (By similarity).  Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP54 2, Signal recognition particle 54 kDa protein 2, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_STRP3
Sequence: MTNSFQNSRRDLRERAFQALFNIEMGAELLAASQFAYGYDKVTGEDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEIKYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: AMPL_BOVIN
Sequence: MFLLPLPAAARVAVRHLSVKRLWAPGPAAADMTKGLVLGIYSKEKEEDEPQFTSAGENFNKLVSGKLREILNISGPPLKAGKTRTFYGLHEDFPSVVVVGLGKKTAGIDEQENWHEGKENIRAAVAAGCRQIQDLEIPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKRKVVVSAKLHGSEDQEAWQRGVLFASGQNLARRLMETPANEMTPTKFAEIVEENLKSASIKTDVFIRPKSWIEEQEMGSFLSVAKGSEEPPVFLEIHYKGSPNASEPPLVFVGKGITFDSGGISIKAAANMDLMRADMGGAATICSAIVSAAKLDLPINIVGLAPLCENMPSGKANKPGDVVRARNGKTIQVDNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDIALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYTRQVIDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHLDIAGVMTNKDEVPYLRKGMAGRPTRTLIEFLFRFSQDSA
What is the function of this protein?
Cytosolic metallopeptidase that catalyzes the removal of unsubstituted N-terminal hydrophobic amino acids from various peptides (PubMed:14583094, PubMed:16519517).  The presence of Zn(2+) ions is essential for the peptidase activity, and the association with other cofactors can modulate the substrate spectificity of the enzyme (PubMed:16519517).  For instance, in the presence of Mn(2+), it displays a specific Cys-Gly hydrolyzing activity of Cys-Gly-S-conjugates (PubMed:16519517).  Involved in the metabolism of glutathione and in the degradation of glutathione S-conjugates, which may play a role in the control of the cell redox status (PubMed:14583094).
What are the official names of this protein?
Cytosol aminopeptidase, Cysteinylglycine-S-conjugate dipeptidase, Leucine aminopeptidase 3, LAP-3, Leucyl aminopeptidase, LAP, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.