PharMolix/UniProtQA huggingface dataset:
Protein: RHO1_CAEEL
Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVRHFCPNVPIILVGNKRDLRSDPQTVRELAKMKQEPVKPEQGRAIAEQIGAFAYLECSAKTKDGIREVFEKATQAALQQKKKKKSKCMIL
What is the function of this protein?
Required for ventral migration of epidermal cells during ventral enclosure in the embryo and for cell elongation (PubMed:24016757).  Also required for ventral migration of P cells during larval development (PubMed:11687661).  Involved in asymmetric spindle positioning during anaphase and establishment of cell polarity during embryo development (PubMed:16921365).  In adults, involved in regulation of multiple processes including locomotion, pharyngeal pumping, fecundity, ovulation, defecation and body morphology (PubMed:21387015).  In body wall muscles, regulates organization of myosin thick filaments downstream of unc-89 (PubMed:18801371).  Association with the oxidase bli-3 promotes ROS production and this interaction may be modulated by memo-1, in order to control the oxidative stress response and longevity (PubMed:28085666).
What are the official names of this protein?
Ras-like GTP-binding protein rhoA.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Associated with the membrane and the cytoskeleton throughout development (PubMed:7798239). Enriched at the anterior cortex in embryos; localization to the anterior cortex requires kin-18 (PubMed:23064028).
Protein: NU3C_PROMM
Sequence: MFALPGYDAFLGFLLISAAVPILALVTNKLLAPRSRTGERELTYESGMEPIGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFHRLGLLAFIEALIFIAILLVALAYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CRSP3_PIG
Sequence: MGFWKFPPFLILSILVLYQAGMLHAAPFRMALGSSFDSATLTEEEMSLLLVAMVKDYVQMKATVLEQETEDFSITTQERSCNTAICVTHKMAGWLSRSGSVVKNNFMPINMGSKVLGRRRRQPQA
What are the official names of this protein?
Calcitonin receptor-stimulating peptide 3, CRSP-3.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXA_NEIG1
Sequence: MTLIHPTAVIDPKAELDSGVKVGAYTVIGPNVRIGANTEIGPHAVINGHTTIGENNRIFQFASLGEIPQDKKYRDEPTKLIIGNGNTIREFTTFNLGTVTGIGETRIGDDNWIMAYCHLAHDCVVGNHTIFANNASLAGHVTVGDYVVLGGYTLVFQFCRIGDYAMTAFAAGVHKDVPPYFMASGYRAEPAGLNSEGMRRNGFTAEQISAVKDVYKTLYHRGIPFEEAKADILRRAETQAELAVFQDFFAQSTRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_SYNY3
Sequence: MHSYTLHAPAKINLFLEILGDRPDGFHELVMVLQSIALGDKITVRANGTDDIRLSCGDSPLANDATNLAYRAAQLMINNFPQAHDNYGGVDITLTKHIPMAAGLAGGSADAAAVLVGLDLLWNLGLTRPELEQLAAQLGSDIPFCIGGGTAIATGRGEILDPLPDGNCFWVVLAKHRSIEVSTPWAYQTYRQKFGKNYLNDDQSQRARRKTIHAGPLLQGIQHRNPGQIASHIHNDLEKVVLPAHQPVAQLRQVLQSAGGLGTMMSGSGPSVFTLCREQAEAEQVLAIAKEKLNDPDVDFWLTHTIGHGIQIMNN
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ATPF_SULSY
Sequence: MKKVVLFTLLITGLSFAGEQKEANESMILFWKAVNTVILLGLVYYFGGKHIKKFLNGRRENVANMVLEAQKMREDSQKALEDAKRKLEEAKYKLEESIKISKETAEREREHAIMQANEIAERIKMQAKETINIEIRKAEAKLKKYAAEKALEVSKSLIESSINPQTSNELIKKTIKGLEA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y892_ATV
Sequence: MSVDQDVVDEAYQYYAEDKRQISDKARKFIEFIDPILRKYSKLFRYYQNFAKFTLEYYYKLFYPFLEKLPENVVEDLKRQIINEIMSNPNQSIRDVLAKAVQKEAQRIEEQLQRRPQRAKQQPQKTKTSEVANQRVSRSAENQGKRGNEEKQQQKTPGKTEEASGAEQESGEEGNQQEESGEEQEGVKGSRSKQREEQEEEVSESEGKQSEESGESESEEGQSSEETQLSSSGEGNQQEEGKGGEGEGAETEEGGRRGEAESEQEEGEETGNGQESSGEAQNGGESGESEGEITESESASEEQTGSKGKSGQQGEEGQQQSGSEGEEGAEQEESGEEGNQQEGVGKQKKRSSRGQESEAGEEPGSAPEETQLSSGEEEAGQESGGETGSEQGFGEEGEQGQESETTGKQKGKKREATESGGGAESESEEGQSPEETQEGGEGGAETEEGGQGSEAEGTAAEGEVGQPSEQGVSSSTGSGQRSEGSEASEEQNAGESGEGSESEGAESIAGEQTGSSSESAGSEQLGSQQGELSLEEGGRGYAHGDEDLLSSPQEINSILQTLSQLRDTVQQLRNYDFYSNAIDERTFDDQNVSEHRKEKEIENLYDTANNVQKLLKDLNVSEGEQNKILQELVTQYSLRRLLGNIATKYKGLLDFVRNKGESEVESRHGSGKGPSSTMGDDLSRLFIKEYAKLSNPIQQKMFLLDYLNGALSIHKSEEKKQGDFLFVIDSSGSMEGNKIATALAIPLVTYKKYKGKRNILVETFSDEPSPIYNIKNIANVLGSMKFGGTNIGSAVLYALKNIDKPDSDYDRKLRESLRKTRTLILLTDGEDEIPDDIAREINSLKKKNKVELLCYGIDLGERGLKTLKEICDEVYAVGSNNFGNIVLKRLVH
What are the official names of this protein?
Putative VWFA domain-containing protein ORF892.
Protein: VSR1_PEA
Sequence: MKCWRLSAILFLGFMLTSLSTARFVVEKNSLSVTSPEKIKGKHDSAIGNFGIPQYGGSMAGNVVYPKDNSKGCKDFDSSFKSRPGALPTILLLDRGSCFFALKVWNAQKAGASAVLVADDIEEPLITMDTPEEDVSSAKYIENITIPSALIGKSFGEKLKDAISGGDMVNVNLDWREAVPHPDDRVEYELWTNSNDECGVKCDMLIEFLKDFKGAAQILEKGGYTQFTPHYITWYCPHAFTLSKQCKSQCINHGRYCAPDPEQDFNTGYDGKDVVVENLRQLCVFKVAKETEKSWVWWDYVTDFQIRCPMKEKKYNKECANSVIKSLGLDVEKIDKCMGDPNADTENSILKEEQDAQIGKGTRGDVTILPTLVVNNRQYRGKLEKGAVLKAICSGFEETTDPAVCLSNDVETNECLTNNGGCWQDKTANIAACKDTFRGRVCECPLVDGVQFKGDGYTTCEVSGHGRCKINNGGCWHDARNGHAFSACLDDGGVKCQCPAGFKGDGVKNCEDIDECKDKKACQCPECSCKNTWGSYNCSCSGDLLYIKDQDTCISKTASQAKSTWAAFWVVLIALAMIAGGGFLVYKYRIRQYMDSEIRAIMAQYMPLDSQEEGPNHVNHQRG
What is the function of this protein?
Vacuolar-sorting receptor (VSR) involved in clathrin-coated vesicles sorting from Golgi apparatus to vacuoles.  Seems to binds preferentially proteins containing a N-terminal NPIR motif.
What are the official names of this protein?
Vacuolar-sorting receptor 1, 80 kDa proaleurein-binding protein, BP-80.
What is the protein family that this protein belongs to?
Belongs to the VSR (BP-80) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Associated to the Golgi apparatus, mostly on the trans-side, to clathrin-coated vesicles (CCVs) and to prevacuolar compartments (PVCs). May also be associated with the plasma membrane.
Protein: KICH_SCHPO
Sequence: MVNFASEVDKNNAFDSAHPSRKCKGSLDCNDPDPIFRHKVLVIIHKLAISSWNRIPLTLCNKLHIKRISGALTNAVYYVAPPEGYHAPKLLLRIYGPHVELFINRQVELENLKRLARHNIGPYLIGEFSNGRFEQYMESTTLTCKTIRDPKLSIYVGRRLCELHNFILLHPHEVLEMPAAWKNCLVWLPKAKAKILGRKHSLAITSEFMKTLEEDFNAYYNWFVEWSRDKKDWFGLKMVFSHNDTQYGNLLKIKAKKRSIPLSQKHRTLVPVDFEYAGPNLCAFDLANYFAEWMADYHHPTHNYLMDRSRYPDFNARKLVYHAYVEQSAVINDLLEIEDASLLKTDISDELKNTFEKQIMNLEESVRAISPAANIGWALWGILQCLEEDDEWEDLSVSSQVADRPEKQLVEGSTVPPIGTSSFDYIGYSSEKFDLFYEGCAALGLNGRNRSTFSYA
What is the function of this protein?
Catalyzes the committed step in the synthesis of phosphatidylcholine by the CDP-choline pathway.
What are the official names of this protein?
Choline kinase, ATP:choline phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYN_GEOUR
Sequence: MYGRTRVSAALAASRPGEELVLKGWVRTVRVGKDVTFLAINDGSCMTSLQVVVEPALPNYQDVCRIGTGSAVAVRGILRESPAAGQKYELAAEELEIIGPADDSYPLQKKRHSFEYLRTIAHLRPRTNTFGAVFRVRSSLAQAVHRFFAERGFLYVHTPIITANDCEGAGELFRVTTLDMARPPLAAGEVDYSGDFFAQATGLTVSGQLEGELFAQAFSDIYTFGPTFRAENSNTARHAAEFWMIEPELAFADLMADAALAEDFLKFLCRHVLDNCGEDMAFFNEQIDKGLLERVRAVADSSFAVMEYTEAITHLKKAKVPFAFPVEWGLDLQSEHERYITEKVVGGPVFLVNYPKDIKAFYMRQNDDGKTVAAMDLLVPKVGEIIGGSQREERLDLLLERMAQMGINEDGLWWYLDSRRWGSCPHAGFGLGFERLLMYLTGMENIRDVIPFPRTPRHAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_CUPTR
Sequence: MPRRREVPKRDVLPDPKFGNVEVAKFMNVLMLDGKKSVAERIVYGAFDQIEKKAGKAPIEVFSVAINNVKPVVEVKSRRVGGANYQVPVEVRPSRRLALAMRWLREAAKKRSEKSMALRLAGELLEAAEGRGGAMKKRDEVHRMAEANKAFSHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PYRB_PSEP1
Sequence: MTPIDAKRPLQLNDQGQLRHFLSLDGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLSADVISLNVSTSSTSKGETLFDTLRNLEAMAADMFVVRHSDSGAAHFIAEHVCPEVAVINGGDGRHAHPTQGMLDMLTIRRHKGSFENLSVAIVGDILHSRVARSDMLALKALGCPDIRVIGPKTLIPIGIEQYGVKVYTDLAEGLKDVDVVIMLRLQRERMAGGLLPSEGEFYRLFGLTTARLAGAKPDAIVMHPGPINRGVEIESAVADGKHSVILNQVTYGIAVRMAVLSMAMSGQNAQRQLDQENAQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: FMT_CHLTR
Sequence: MSLRVVYLGTPQFAATVLKTLLDAHTHIVGVVTRADKPQKRSSKLISSPVKQLALSKNIPLLQPIKTTDPAFLAQLREWQADVFIVVAYGVILKQELLDIPTYGCYNLHAGLLPAYRGAAPIQRCIMDGGVLSGNTVIRMDAGMDTGDIANVNYVAIGEDMTAGGLAEALAASGGELLLKTLQEIEAGTVRHVPQNEAMATLAPKLTKEEGGIHWDAPASQVYAHIRGVSPAPGAWTRYLSQGKEARRLGVLSARMESFSGNYGDPGEVLGVSGEDLLIACRQGALRLRMVQPEGKALMKAKDFFNGQSRLVSKLF
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: G6PI_XYLFM
Sequence: MHNGFDALQLHANRLRGVTIPDLLAAELKRPEQYARQVGPLYFNFARQKYDCVALEALFALARNHNVTGAFQRMFCGEQVNVTEGRAVLHTALRGDLSGTSVAVAAYTAAAKVRERMYALIAGLDASEVTDIVSVGIGGSDLGPRLVVDALRPISQGRFRVHFVSNVDGAAMRRTLDMLDPSRTAGILISKTFGTQETLLNGRILYDWLGGSERLYAVSANPERAVHAFDIVPTQVLPIWDWVGGRYSLWSAVGFPIALAIGSQRFEELLAGAAEFDAYALRVPLEENVAVLHGLTAVWNRNFLGCATYAVMAYDQRLALLPAYLQQLVMESLGKRVKCDGTPVDRDTVPVWWGGVGTDVQHSFFQALHQGTNIVPADFIGTIRNDDLYTENHFALNANLLAQIEVLANGQLSDDPHRVYPGGNPSTLILLDALTPQALGGLIAMYEHSVYVQSVIWGINAFDQFGVELGKHLAVQLLPALKGESVEVVDPVTRAVLVRLRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_METKA
Sequence: MLKVLLVGSGAREHAIAEALCGAPDEDVELYAFMGNRNPGIIRLAEDYVVGDPTDVEAVARAAADWNVDFAVVGPEDPLAEGVADRLEEEGIPTFGPKRGPARIEWDKGFARELMEKYDIPGRPEFGIFEDPDEACDFIDELGKPVAVKPAGLTGGKGVKVVGDQLKNLDEAKEYVKEIFEEDIGGIPKVIIEEKCVGEEYTIQAYTDGEKVIPTPAVQDHPHAYEGDKGPITGGMGSYSCPDGLLPFITKEDYERSVEILERTVEAIKKETGEPYRGVLYGQFMLTAEGPVVIEFNCRYGDPEAMNILPIAEGDIVTLHASIAEGSMEGEIEFLEKATVCKYVVPEGYPESSEGEGDVIEVDEECIHRYDAVPYYASVNLDEDGKIRMTSSRALAIVGIGDELEQAEEAAESAIRECVSGERIRHRSDIGKHETVEKRVRRMKRIRGE
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: SHO1_YEAS7
Sequence: MSISSKIRPTPRKPSRMATDHSFKMKNFYADPFAISSISLAIVSWVIAIGGSISSASTNESFPRFTWWGIVYQFLTICSLMLFYCFDLVDHYRIFITTSIAVAFVYNTNSATNLVYADGSKKAAASAGVILLSIINLIWILYYGGDNASPTNRWIDSFSIKGIRPSPLENSLHRARRRGNRNTTPYQNNVYNDAIRDSGYATQFDGYPQQQPSHTNYVSSTALAGFENTQPNTSEAVNLHLNTLQQHINSASNAKETNDNSNNQTNTNIGNTFDTDFSNGNTETTMGDTLGLYSDIGDDNFIYKAKALYPYDADDDDAYEISFEQNEILQVSDIEGRWWKARRANGETGIIPSNYVQLIDGPEEMHR
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Detects changes in external osmolarity and activates PBS2 through the stimulation of STE11 and targets PBS2 to the plasma membrane.  PBS2 activation leads to changes in glycerol production that helps to balance the intracellular and external osmotic pressures.  Activates also HOG1 in response to heat stress and mediates resistance to oxidative stress.  Involved in the regulation of the mating pathway.  May be a receptor that feeds into the pseudohyphal growth pathway (By similarity).
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1, Suppressor of SUA8-1 mutation, Synthetic high osmolarity-sensitive protein 1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bud. Bud neck. Cell projection. Note=Localizes at the tip of the mating projection during conjugation.
Protein: FENR_PICTO
Sequence: MEDYDLVIIGAGPTGLFATFLAGLRDIKSITLEALDYVGGQIPELYPEKPVYDVQGIPKINAIKLRDQMYEQAKTFNNRIELNSKVTDIIKENDIFKIEVNGVYKYNARAVLLCTGIGDFTPRKIGCEGEDRFFNKGLTYTVKDTEKFRDLTVAVVGGGDSALDYATELANTARHVYIIHHSENFKAAEKTIDLARKNEKITFIVNSSVISIDGGSKLESIKIKNELTNDISELGLDALVVAIGHVGRANIYKSLPLQLSPNKRGVLVNSKLETNIPGIYAAGDVASVEGEPANPLIAIGGAQAYQAINYIKKYINPQASFFGGHSSNLKI
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: NUOC_BURO0
Sequence: MASKIETLKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDLCGVDYQTFGDGAYDGPRFAAVSHLLSVTNNWRLRLRAFAPDDDLPIVASLVDIWTSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
Protein: NARY_ECOLI
Sequence: MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNVETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGNKMGVITKIFANPVVPQIDDYYEPFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNFEAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRGWRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDADRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIDAAQRSPVYKMAMDWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLANMLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIANYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVRDKAEGE
What is the function of this protein?
This is a second nitrate reductase enzyme which can substitute for the NRA enzyme and allows E. coli to use nitrate as an electron acceptor during anaerobic growth.  The beta chain is an electron transfer unit containing four cysteine clusters involved in the formation of iron-sulfur centers.  Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit.
What are the official names of this protein?
Respiratory nitrate reductase 2 beta chain.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ILVC_PSEAB
Sequence: MRVFYDKDCDLSIIQGKKVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHGLKVADVKTAVAAADVVMILTPDEFQGRLYKEEIEPNLKKGATLAFAHGFSIHYNQVVPRADLDVIMIAPKAPGHTVRSEFVKGGGIPDLIAIYQDASGNAKNVALSYACGVGGGRTGIIETTFKDETETDLFGEQAVLCGGCVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINAESRAAMRNALKRIQDGEYAKMFITEGAANYPSMTAYRRNNAAHPIEQIGEKLRAMMPWIAANKIVDKSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CCKAR_HUMAN
Sequence: MDVVDSLLVNGSNITPPCELGLENETLFCLDQPRPSKEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGARGEVGEEEEGGTTGASLSRFSYSHMSASVPPQ
What is the function of this protein?
Receptor for cholecystokinin.  Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach.  Has a 1000-fold higher affinity for CCK rather than for gastrin.  It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system.  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Cholecystokinin receptor type A, CCK-A receptor, CCK-AR, Cholecystokinin-1 receptor, CCK1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CBHA_NEOFI
Sequence: MHQRALLFSALAVAANAQQVGTQKPETHPPLTWQKCTAAGSCSQQSGSVVIDANWRWLHSTKDTTNCYTGNTWNTELCPDNESCAQNCAVDGADYAGTYGVTTSGSELKLSFVTGANVGSRLYLMQDDETYQHFNLLNNEFTFDVDVSNLPCGLNGALYFVAMDADGGMSKYPSNKAGAKYGTGYCDSQCPRDLKFINGMANVEGWKPSSNDKNAGVGGHGSCCPEMDIWEANSISTAVTPHPCDDVSQTMCSGDACGGTYSATRYAGTCDPDGCDFNPFRMGNESFYGPGKIVDTKSEMTVVTQFITADGTDTGALSEIKRLYVQNGKVIANSVSNVADVSGNSISSDFCTAQKKAFGDEDIFAKHGGLSGMGKALSEMVLIMSIWDDHHSSMMWLDSTYPTDADPSKPGVARGTCEHGAGDPEKVESQHPDASVTFSNIKFGPIGSTYKA
What is the function of this protein?
The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Probable 1,4-beta-D-glucan cellobiohydrolase A, Beta-glucancellobiohydrolase A, Cellobiohydrolase D, Exocellobiohydrolase A, Exoglucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 7 (cellulase C) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC1_PROMP
Sequence: MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDVGDHKDLKYKQLLTEDEWLEIEDEVYAEDSTIENEPVVGIGAEALKQLLEDLDLNQIAEELREEITNSKGQKRAKLIKRIRVIDNFLATNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKGDDEVMQVLQEVIEGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVHVPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNFKKPNFGDNQKTYASLEDVIFAFEDKRVGLHEWVWVRFNGEVDDDEEANKPKESKELEDGSRLETWNFRRDRFDSQNNLISRFILTTVGRVVMNHTIIDSVSKT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: MDTC_PROMH
Sequence: MKLFALFIQRPVATTLLSLAISLCGALGFMLLPVAPLPQVDYPVINIYASLPGASPETMASSVATPLERSLGRIAGIDEMTSSSALGSTSITLVFDLNKDINTAARDVQAALNASQSLLPSGMPSRPRYYKSNPSDAPIMILTLTSETQNTGELYDLASTRLAQKISQIEGVSEVSVGGGSLPAVRVALNPDALFNQNVSLDDVRKAISQSNVRRPQGFIHNDENRWQIQTNDELSKAQDYRPIIVHYNQDAIVRLSDVAQVTDSVQNARAAGMSGGEPAILLVIRREAGANIIETVNRIRDELPELRELLPASVNLKVAQDRTPTIRASLAEVERALAIAVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFSAMYLCGFSLNNLSLMALTVATGFVVDDAIVVLENISRHIENGLKPKQAALKGVSEVGFTVLSMSISLVAVFIPLLLMDGLVGRLFKEFAITLTTAIGISLFVSLTLTPMMCAHLLKGIKPKAQSHLRGFGKLIFRLQQGYSVTLQAALRHKRWIMAIFITTLGLNAYLYISAPKTFFPDQDTGRLMGFVRADQSISFQSMKEKMTRFMQEINADKDVDSVTGFTGGGRINSGFMFISLNPLSERTDSANQVINRLRIKLANEPGATLFLMPVQDVRAGGRQANASYQFTLLADDLSELRKWEPLIRKALGELPELVDVNSDKEDKGAEMALTYDRDTMSQLGINVSDANNLLNNAFGQRQISTIYAPLNQYKVVMEVSEQYTQDVSALDKMYVMNTQGERIPLSAFASWYPANAPLSVNHQGLSAASTIAFNVPEGYTLSDAINAIERTMTELGVPNTVRGTFAGTAQIFQETIKSQLILILAAIVTVYIVLGVLYESYIHPLTILSTLPSAGVGALLALRLFDTPFSLIALIGIMLLIGIVKKNAIIMVDFAITAQREGKLSAQEAIIQASLLRFRPIIMTTLAALFGALPLMLSSGDGAELRQPLGITIVGGLLMSQLLTLYTTPIIYLFFDGVRQRWQQRRHNKKEANA
What are the official names of this protein?
Multidrug resistance protein MdtC, Multidrug transporter MdtC.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.