PharMolix/UniProtQA huggingface dataset:
Protein: CYB_AERVU
Sequence: MDPNLRKSHPLLKMINNSLIDLPTPSNISAWWNFGSLLGTCLATQIITGLLLAMHYTADTTVAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGFYYGSYLYQETWNTGVVLLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTGFFALHFLLPFLIAGLTLIHLTLLHESGSNNPLGIVSNCDKIPFHPYFSTKDLLGFIIMLTPLMTLALFSPNLLGDPKNFTPANPLVTPPHIKPEWYFLFAYAILRSIPNQLGGVLALTASVLVLFLSPFLHKSKQRTMTFRPLSQILFWTLVANLLILTWVGSQPVEHPFIIIGQLASLTYFTILLILFPLIGALEYKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPS1_KLULA
Sequence: MVNQDISKLSLNECPGSVIVISNRLPVTIKKDEKTGEYEYSMSSGGLVTALQGLKKSTTFQWYGWPGLEVPDEDKAKVKRELLEKFNAIPIFLSDEVADLHYNGFSNSILWPLFHYHPGEITFDDTAWLAYNEANMAFADEIEGNINDNDVVWVHDYHLMLLPEMIRQRVIAKKLKNIKIGWFLHTPFPSSEIYRILPVRQEILKGVLSCDLIGFHTYDYARHFLSAVQRILNVNTLPNGVEFDGRFVNVGAFPIGIDVETFTEGLKQDAVIKRIKELKESFKGCKIIIGVDRLDYIKGVPQKLHALEVFLGAHPEWIGKVVLVQVAVPSRGDVEEYQYLRSVVNELVGRINGQFGTAEFVPIHFMHRSIPFQELISLYAVSDVCLVSSTRDGMNLVSYEYISCQEEKKGTLILSEFTGAAQSLNGALIVNPWNTDDLAESINEALTVPEEKRAANWEKLYKYISKYTSAFWGENFVHELYRLGSSNN
What is the function of this protein?
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process.  Can function independently of the complex.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit, Trehalose-6-phosphate synthase, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: NNRD_YEAST
Sequence: MLAELSHRELIKLAQKRCIPPLLPKFHKGQSGGRVCIIGGCEDYTGAPYFSANATALMGCDLTHVICEYNAGTVIKSYTPNLMVHPYLRMSNTKLDVDMDEQRKKINSLLDRIHVVVIGPGLGRDPLMLKSIKDIIRYILEKHEGKIPLVIDADGLFLVTQDSEVKEMLKSYPKGRVILTPNVVEFKRLCDAIGKKGDSHSEMGSLIAQELNCIVVEKGQSDKIFSPDSEKDMLTNSEEGSNKRVGGQGDTLTGAISCMLAFSRAMYDFKICEQEEKGESSNDKPLKNWVDYAMLSCYAGCTITRECSRLGFKAKGRAMQTTDLNDRVGEVFAKLFG
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase, Nicotinamide nucleotide repair protein 2.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_PECCP
Sequence: MAENQYYGTGRRKSSAARVFIKPGNGNIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRGELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CSG_HALVD
Sequence: MTKLKDQTRAILLATLMVTSVFAGAIAFTGSAAAERGNLDADSESFNKTIQSGDRVFLGEEISTDAGLGASNPLLTGTAGNSEGVSLDLSSPIPQTTENQPLGTYDVDGSGSATTPNVTLLAPRITDSEILTSSGGDVTGSAISSSDAGNLYVNADYNYESAEKVEVTVEDPSGTDITNEVLSGTDTFVDDGSIGSTSSTGGGVGIDMSDQDAGEYTIILEGAEDLDFGDATETMTLTISSQDEIGIELDSESVTQGTDVQYTVTNGIDGNEHVVAMDLSDLQNDATTEQAKEVFRNIGDTSEVGIANSSATNTSGSSTGPTVETADIAYAVVEIDGASAVGGIETQYLDDSEVDLEVYDAGVSATAAVGQDATNDITLTIEEGGTTLSSPTGQYVVGSEVDINGTATSSDSVAIYVRDDGDWQLLEIGGDNEISVDSDDTFEEEDIALSGLSGDGSSILSLTGTYRIGVIDASDADVGGDGSVDDSLTTSEFTSGVSSSNSIRVTDQALTGQFTTINGQVAPVETGTVDINGTASGANSVLVIFVDERGNVNYQEVSVDSDGTYDEDDITVGLTQGRVTAHILSVGRDSAIGDGSLPSGPSNGATLNDLTGYLDTLDQNNNNGEQINELIASETVDETASDDLIVTETFRLAESSTSIDSIYPDAAEAAGINPVATGETMVIAGSTNLKPDDNTISIEVTNEDGTSVALEDTDEWNNDGQWMVEIDTTDFETGTFTVEADDGDNTDTVNVEVVSEREDTTTSSDNATDTTTTTDGPTETTTTAEPTETTEEPTEETTTSSNTPGFGIAVALVALVGAALLALRREN
What is the function of this protein?
S-layer protein.  The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of the cell.
What are the official names of this protein?
Cell surface glycoprotein, S-layer glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the halobacterial S-layer protein family.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Cell membrane. Note=This archaeon is covered by an S-layer with hexagonal symmetry. S-layer glycoproteins are anchored to the plasma membrane as well as being surface-exposed (PubMed:2123862, PubMed:1569073). Bound to the membrane via a covalent lipid-mediated ArtA-dependent anchoring mechanism (PubMed:26712937).
Protein: TRUA1_BACCZ
Sequence: MDRIKCTVAYDGMHFCGYQIQPQHRTVQQEIEKALQKLHKGELVRVQASGRTDSTVHAKGQVIHFDTPLSLEEWQWSNALNTMLPDDIVITQVEKKTEEFHARYGVERKEYRYRVLVSKTADVFRRNYVYQYPYPLEVNSIRKAIPYFIGTHDFTSFCSAKTDKKDKVRTIYEIELIEQDDELIFRFVGNGFLYNMVRIIVGTLLNVGQGKLDPDSIPEILAKQNRQFAGKMAPGHGLYLWQVNYNN
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 1, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 1, tRNA-uridine isomerase I 1.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CB60F_ARATH
Sequence: MENSMNNRGHGHNQEHADNLPESKRQKLPALASVIVEAVKVDSLQRLCSSLEPLFRRIVSEEVERAISRLENSKSTSRSTEPNKIQGLDGRNLQLRFRTRMPPHLFTGGKVEGEQGSAIHVVLIDANTGNVIQTGEESMTKLNIVVLDGDFNDEDDKDWTREHFESFEVKEREGKRPILTGDRHVIIKEGVGTLGKLTFTDNSSWIRSRKFRLGVKPATGFHIREAKTEPFAVKDHRGELYKKHYPPVLHDEVWRLDKIAKDGALHKKLLKSNIVTVEDFLQILMKDPQKLRSLLGSGMSNRMWDNTVEHAKTCVLGGKLYAYYTDQTHQTAVVFNHIYEFQGLIANGHFLSSESLNHDQKISADTLVKTAYENWHKVVEYGGKLLNCLPVAKKGIKSLPEPKMAQNHQTQQKALQCQQTVNGYSSDPQHLIEYPFVQQPCYQLRDYTSMESSSVSGSYNGGLEDIFTEEIRARSSEMLETDNMQRLLKTFGISGGFGNRDESIYGFSDQYEAQIDKGYMREGGRGAGKAVVGWLKLKAALRWGIFIRKKAAERRPQIVEID
What is the function of this protein?
Transcription activator that binds DNA in a sequence-specific manner, likely 5'-GAAATTTTGG-3', to promote the expression of target genes.
What are the official names of this protein?
Calmodulin-binding protein 60 F.
What is the protein family that this protein belongs to?
Belongs to the plant ACBP60 protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPF_SHIB3
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVIEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSIGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_NEIMB
Sequence: MMKPHNLFQFLAVCSLTVAVASAQAGAVDALKQFNNDADGISGSFTQTVQSKKKTQTAHGTFKILRPGLFKWEYTKPYRQTIVGDGQTVWLYDVDLAQVTKSSQDQAIGGSPAAILSNKTALESSYTLKEDGSSNGIDYVLATPKRNNAGYQYIRIGFKGGNLAAMQLKDSFGNQTSISFGGLNTNPQLSRGAFKFTPPKGVDVLSN
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NOL4_HUMAN
Sequence: MESERDMYRQFQDWCLRTYGDSGKTKTVTRKKYERIVQLLNGSESSSTDNAKFKFWVKSKGFQLGQPDEVRGGGGGAKQVLYVPVKTTDGVGVDEKLSLRRVAVVEDFFDIIYSMHVETGPNGEQIRKHAGQKRTYKAISESYAFLPREAVTRFLMSCSECQKRMHLNPDGTDHKDNGKPPTLVTSMIDYNMPITMAYMKHMKLQLLNSQQDEDESSIESDEFDMSDSTRMSAVNSDLSSNLEERMQSPQNLHGQQDDDSAAESFNGNETLGHSSIASGGTHSREMGDSNSDGKTGLEQDEQPLNLSDSPLSAQLTSEYRIDDHNSNGKNKYKNLLISDLKMEREARENGSKSPAHSYSSYDSGKNESVDRGAEDLSLNRGDEDEDDHEDHDDSEKVNETDGVEAERLKAFNMFVRLFVDENLDRMVPISKQPKEKIQAIIDSCRRQFPEYQERARKRIRTYLKSCRRMKRSGFEMSRPIPSHLTSAVAESILASACESESRNAAKRMRLERQQDESAPADKQCKPEATQATYSTSAVPGSQDVLYINGNGTYSYHSYRGLGGGLLNLNDASSSGPTDLSMKRQLATSSGSSSSSNSRPQLSPTEINAVRQLVAGYRESAAFLLRSADELENLILQQN
What are the official names of this protein?
Nucleolar protein 4, Nucleolar-localized protein.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: STF3_MYCTU
Sequence: MKALRSSSRLSRWREWAAPLWVGCNFSAWMRLLIRNRFAVHHSRWHFAVLYTFLSMVNSCLGLWQKIVFGRRVAETVIADPPIFIVGHWRTGTTLLHELLVVDDRHTGPTGYECLAPHHFLLTEWFAPYVEFLVSKHRAMDNMDLSLHHPQEDEFVWCMQGLPSPYLTIAFPNRPPQYEEYLDLEQVAPRELEIWKRTLFRFVQQVYFRRRKTVILKNPTHSFRIKVLLEVFPQAKFIHIVRDPYVVYPSTIHLHKALYRIHGLQQPTFDGLDDKVVSTYVDLYRKLDEGRELVDPTRFYELRYEDLIGDPEGQLRRLYQHLGLGDFECYLPRLRQYLADHADYKTNSYQLTVEQRAIVDEHWGEIIDRYGYDRHTPEPARLRPAVGG
What is the function of this protein?
Involved in the biosynthesis of sulfomenaquinone (SMK, initially named S881 on the basis of its mass), which is localized in the outer envelope of M. tuberculosis and negatively regulates its virulence (PubMed:16537518, PubMed:27933784).  Catalyzes the transfer of a sulfonate group from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to omega-hydroxy-beta-dihydromenaquinone-9, generating omega-sulfo-beta-dihydromenaquinone-9 (sulfomenaquinone) (PubMed:16537518, PubMed:18928249).
What are the official names of this protein?
Omega-hydroxy-beta-dihydromenaquinone-9 sulfotransferase Stf3, PAPS-dependent sulfotransferase Stf3.
What is the protein family that this protein belongs to?
Belongs to the Stf3 family.
Protein: KA293_LYCMC
Sequence: MKSVCGVLIILVVLTTMLSISTFSTVGAEADCPISEAIKCVEKCNQKVEVCEPGVCKCSG
What is the function of this protein?
Weakly inhibits the Kv1. 3/KCNA3 channel (1 uM of thetoxin inhibits currents by 13. 2%) and Kv7. 1/KCNQ1 channel (10 uM of the toxin inhibits currents by 27. 7%).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 29.3, Neurotoxin LmKTx95, Neurotoxin-E.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 29 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGJ_ORYSJ
Sequence: MPPPSLLLLHPRTPLPHHHRSSFRTSSPRPSRMVCAAAEGFISAAPILLPDGPWKQVEGGVTAAKGFKAAGIYGGLRAKGEKPDLALVACDVDATVAGAFTTNVVAAAPVLYCKRVLNSSKTARAVLINAGQANAATGDAGYQDTVDSADAVAKLLNVSTNDILIQSTGVIGQRIKKEALVNSLHRLVGSLSSSIEGANSAAVAITTTDLVSKSIAVQTEIGGVPIKIGGMAKGSGMIHPNMATMLGVLTTDAQVSSDVWREMVRTSVSRSFNQITVDGDTSTNDCVIALASGLSGLSSILTHDSTEAQQFQACLDAVMQGLAKSIAWDGEGATCLIEVTVAGANNEAEAAKIARSVASSSLVKAAVFGRDPNWGRIACSVGYSGIQFDADQLDISLGAIPLMKNGQPLPFDRSAASKYLKDAGDIHGTVNIDVSVGRGGGSGKAWGCDLSYKYVEINAEYTT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL3_TETTH
Sequence: MSHRKFEAPRHGSLGFRPRRRTRHHRGRCRSFPKDDPSKKPHLTAFTGFKAGMTHILREVDRSGSRHNKKEVVEAVTVIECPPMTIVGVVGYIDTPRGLRALTTVWAKTIDNNTKKRFYKNWANSNKKAFTHHEKNFDQKAQDLLLKRIEKYCSVVRVIAHTNMSKLNLRQKKNHILEIQVNGGKVAEKVAFAKSLLEKEVKVDSIFAENEMLDVLGVTKGKGFAGVIKRFGVKHLQKKTHRGYRKVGCIGAWHPSRIRFTVPRAGQLGYHHRTETNKKVYRVGKGDDASNASTAGDVTDKAITPLGGFPHYGVVKNDFIMIKGCCVGPKKRVLTLRKSIIPQTHGAAKEIINLKFIDTSSKIGHGRFQTVEEKDKFFGRDRTKKVEAKSE
What is the function of this protein?
The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
What are the official names of this protein?
Ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMO_RAT
Sequence: MRGLEKQGPSATAAPCGCAQPALETGNLLTEPIGYLESCFSAKIGTPRQPSICSQSRACLKIRKSIFNNPEHSLMGLEQFSHVWILFVFHKNGHLNYKAKVQPPRLNGAKTGVFSTRSPHRPNAIGLTLAKLEKVEGGAVYLSGIDMIHGTPVLDIKPYIADYDSPQNLEPQTKHHKLRAAGPSDATANSCDQQLLSGCEKAQPCHSTKEKPKCREHRTSDENSQKFRDTSEIQHTLPEDRERAVDLALESSREETMDEPEDQLGPQELKSFLEEGTDRPRKVEGALVLRGSSAETRWDASCHARTADRVPCSVVPSWVKEAPVATLQVRFTPHAEMDLRKLSSGGASQTSFKYFHSAEEAKCAIEAMLSADPRSVYRRKLCEDRLFFFTVDIAHVTCWFGDGFAEVLRIKLASEPVEVADPEESLVALGS
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase responsible for the addition of the methyl group in the formation of N6-methyl-N6-threonylcarbamoyladenosine at position 37 (m(6)t(6)A37) of the tRNA anticodon loop of tRNA(Ser)(GCU).  The methyl group of m(6)t(6)A37 may improve the efficiency of the tRNA decoding ability.  May bind to tRNA.
What are the official names of this protein?
tRNA (adenine(37)-N6)-methyltransferase, tRNA methyltransferase O.
What is the protein family that this protein belongs to?
Belongs to the tRNA methyltransferase O family.
Protein: ZAPD_ECO45
Sequence: MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFFRNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVLISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIASLNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGHKSRFAIRFMPLDSENGQVPERLDFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: COX5A_GORGO
Sequence: MLGAALRRCAVAATTRAGPRGLLHSARTPGPAAAIQSVRCYSHGSQETDEEFDARWVTYFNKPDIDAWELRKGINTLVTYDMVPEPKIIDAALRACRRLNEFASTVRILEAVKDKAGPHKEIYPYVIQELRPTLNELGISTPEELGLDKV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: TRPD_THEPX
Sequence: MLQEAIKKIVSKENLEEREAYAVMNEIMSGNATPSLIGGILIGLRLKGESVEEITGFAKAMRDNAIKLELASDYVIDTCGTGGDGGKTFNISTAVAIIASAAGVKVAKHGNRAVSSKSGSADVLMELGFDIEMVPEKTKRLIEEKGMGFLFAPKYHVAMKNVAGIRKELGTRTVFNVLGPLTNPAFVKGQVLGVYDKELTHPLAEVLLRLGTEKAMVVHGFDGLDEITTTSPTFVSEVKEGKVIDYVIDPEDYGIPYAKLEDLEGKDAKENAQIILNILKGEKGPKRDIVVLNAAAALYIGKVVEDLKEGIKVANYLIDTGLALDKLTEILEYQRRLN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL14_SHEFN
Sequence: MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRAKAKKGDVYNAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANLAPIGTRIFGPVTRELRNDKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DNAA_RICCN
Sequence: MSTNQIILTDQGDNYVNVWSHVAQDLYNHYGETLYNSWFSKVNFIESSLNTVILCAPTNFVRDWIKSKYSMVILQLFQHYNNTIKSIEIITKELPGTTQTVTELPTKTFADIGSSELNSENIFSTLDVRFTFDNFVVGAPNELAYAAARAVAESSGAVSESNPLFLYGGVGLGKTHLMHAIGWYIKQHNPSRKVIYMSAEKFMYQFVKALRNKEVISFKEKFRSVDVLMIDDIQFICGKDSTQEEFFHTFNTLIDNNRQMVISCDRSPSDLDNIEDRIKSRLGWGLVADVHSTTYELRLGILESKIEQMNVKIPKDVIDFLASKIVSNVRELEGALNKVIAHSNFTLKEITLENTQNILRDLLRSNERIITVEDIQKKVASRYNIKLSDMSSSRRLREVARPRQIAMYLSKALTPKSLADIGKKFGKKDHTTVMHAIKKVEELLENDIELREEINLLMKILQN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PALLD_HUMAN
Sequence: MSGTSSHESFYDSLSDMQEESKNTDFFPGLSAFLSQEEINKSLDLARRAIADSETEDFDSEKEISQIFSTSPASLCEHPSHKETKLGEHASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAMSPLLTRPSYIRSLRKAEKRGAKTPSTNVKPKTPHQRKGGPQSQLCDKAANLIEELTSIFKAAKPRNRSPNGESSSPDSGYLSPKNQPSALLSASASQSPMEDQGEMEREVKSPGARHCYQDNQDLAVPHNRKSHPQPHSALHFPAAPRFIQKLRSQEVAEGSRVYLECRVTGNPTPRVRWFCEGKELHNTPDIQIHCEGGDLHTLIIAEAFEDDTGRYTCLATNPSGSDTTSAEVFIEGASSTDSDSESLAFKSRAGAMPQAQKKTTSVSLTIGSSSPKTGVTTAVIQPLSVPVQQVHSPTSYLCRPDGTTTAYFPPVFTKELQNTAVAEGQVVVLECRVRGAPPLQVQWFRQGSEIQDSPDFRILQKKPRSTAEPEEICTLVIAETFPEDAGIFTCSARNDYGSATSTAQLVVTSANTENCSYESMGESNNDHFQHFPPPPPILETSSLELASKKPSEIQQVNNPELGLSRAALQMQFNAAERETNGVHPSRGVNGLINGKANSNKSLPTPAVLLSPTKEPPPLLAKPKLDPLKLQQLQNQIRLEQEAGARQPPPAPRSAPPSPPFPPPPAFPELAACTPPASPEPMSALASRSAPAMQSSGSFNYARPKQFIAAQNLGPASGHGTPASSPSSSSLPSPMSPTPRQFGRAPVPPFAQPFGAEPEAPWGSSSPSPPPPPPPVFSPTAAFPVPDVFPLPPPPPPLPSPGQASHCSSPATRFGHSQTPAAFLSALLPSQPPPAAVNALGLPKGVTPAGFPKKASRTARIASDEEIQGTKDAVIQDLERKLRFKEDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQEYKVSSCEQRLISEIEYRLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYKIFEGMPVTFTCRVAGNPKPKIYWFKDGKQISPKSDHYTIQRDLDGTCSLHTTASTLDDDGNYTIMAANPQGRISCTGRLMVQAVNQRGRSPRSPSGHPHVRRPRSRSRDSGDENEPIQERFFRPHFLQAPGDLTVQEGKLCRMDCKVSGLPTPDLSWQLDGKPVRPDSAHKMLVRENGVHSLIIEPVTSRDAGIYTCIATNRAGQNSFSLELVVAAKEAHKPPVFIEKLQNTGVADGYPVRLECRVLGVPPPQIFWKKENESLTHSTDRVSMHQDNHGYICLLIQGATKEDAGWYTVSAKNEAGIVSCTARLDVYTQWHQQSQSTKPKKVRPSASRYAALSDQGLDIKAAFQPEANPSHLTLNTALVESEDL
What is the function of this protein?
Cytoskeletal protein required for organization of normal actin cytoskeleton.  Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types.  May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays.  Binds to proteins that bind to either monomeric or filamentous actin.  Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles.  Different isoforms may have functional differences.  Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation.  Involved in targeting ACTN to specific subcellular foci.
What are the official names of this protein?
Palladin, SIH002, Sarcoma antigen NY-SAR-77.
What is the protein family that this protein belongs to?
Belongs to the myotilin/palladin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, myofibril, sarcomere, Z line. Cell projection, ruffle. Cell projection, podosome. Cell projection, lamellipodium. Cell projection, axon. Cell projection, growth cone. Note=Localizes to stress fibers and Z lines (PubMed:11598191, PubMed:16125169, PubMed:17322171, PubMed:17537434). Preferentially expressed in the excitatory presynaptic terminals (By similarity).
Protein: RS12_STRA5
Sequence: MPTINQLVRKPRKSKVEKSDSPALNIGYNSHRKVHTKLSAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DEFA1_ORNAN
Sequence: MQTLSFLLALLFLVAQTPAQPTGEGEKGGTIQEPEATEAQDTAAVLMAAGAADGDDSDTKQLDTTFCRCRVSCNILEKYSGKCELSGRTARICCRKIK
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Defensin-A1, DefA1, OaDefA1.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1308_METJA
Sequence: MVDFMDYNDFQKKLDKEEHGDGITVGAVYTGEFTLYLLFIFGALIIGRVYGKTLMTLFGLAALAFSLSVSPLIFKFKEENSNAINYQLFWLSIFLGAIAFCIYMTTRW
What are the official names of this protein?
Uncharacterized protein MJ1308.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRFA_EDWI9
Sequence: MIKVSNALQRILIGAALALFGGGAQAAAADSAAAAEKAPPKIEARNDRFAAPHPDQYASWKATAEQSEISDALAEDPRLVILWAGYAFAKDYNKPRGHAYALTDVRETLRTGAPMKPEDGPQPMACWSCKSPDVARVIAEQGEAAYFHGMWARGGPEIVNALGCADCHNTASDDFAAGKPALQLSRPYAARALEAIGKPFDKANRIDQQSMVCGQCHVEYYFSGKDKTVKFPWDQGTSVDEIEAYYDGIAFTDWVNPLSKAPMLKAQHPDYETWRAGIHGQNNISCVDCHMPKVQNAEGKLYTSHKIGNPFDSFEQTCRTCHTQDKATLQQTVAKRKQDVNEIKLKVEDQLVRAHFEAKAAWAAGASEAEMQPILTDIRHAQWRWDFSIASHGVHMHAPDVALRMLGTALDKAANARTQLVRVLANHGVNDAVPLPDISTKALAQQALGMNMQQFTQEKQTFLNTVVPEWEAQARSAGRLDH
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.