PharMolix/UniProtQA huggingface dataset:
Protein: PYRB_BRUMB
Sequence: MTNQTVSPLFPHRHLLGIKGLSPLDILCLLDLADQEIAVSRQPEKKKSVLRGRTQINLFFEASTRTQSSFELAGKRLGADVMNMSVGNSSVKKGETLIDTAMTLNAMQPDILVIRHASAGAAALLAQKVGCSVVNAGDGAHEHPTQALLDALTIRRAKGQIENLIVAICGDVLHSRVARSNILLLNALGARVRVVAPSTLLPAGMADMSVEVFNSMEEGLKDADVVMMLRLQRERMAGSFVPSVREYFHFYGLDREKLKFAKPDALVMHPGPMNRGVEIASDVADGPQSVIQQQVEMGVAVRMAVMEALLDPRRNPGNGEPA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ACKA_ECOLI
Sequence: MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARIKWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSSVVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEESYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVSAIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGLLGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGIGENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIAQDASRLTA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.  During anaerobic growth of the organism, this enzyme is also involved in the synthesis of most of the ATP formed catabolically.  The main pathway for acetate production during exponential phase (PubMed:16080684).
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_ADICA
Sequence: MAAGNSSWARAAFTFKATVFKKSRYVIYYSLLEHRFSLSLWGILKYSGIYFCTEILRSFPKKRCKSHPYRVDGYPAGSCLDPPLHEPLDTSTPKKISLVSCSNSYMRNKTDNGKVGSRNVSEYKLEGDFASTSKSIYYKLNNLEKMNRKLAWIEAVSSEFSFWEKLRSKQIFPFQNEKDLIAEPFNYELAVSHRRPVIYESISLVPRSVTRTLSRFKAELTNQSNLNLSVHNKFDLAKNQASVSLQYVGFLLFLFPIQIAIENWFLEPRIRGWWNIRQIQLFSNVFQEENALKQLREAEALFWLDDVIGNLADTQLQNFDTDARNETTRLAMMYDELNIQLLLRLATNAISIATLFPLLIFGRKRLAVLNSWIQELFYSLNDTMKAFSILLLTDLCVGFHSPHGWEILVQSLFEYFGLTPNKYVTPCFVSTFPVILDTLFKYWIFRHLNRTSPSIVATYHTMSE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: RNPA_PHOPR
Sequence: MNKLAFSRELRLLTPEHYKKVFQQAHRAGSPHLTILARPNDLNHPRLGLAVPKKQIKTAPGRNHFKRIVRESFRLKQHDLPANDFVVIAKKSASELSNEELFKLLDKLWHRLSRLSRG
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: YEW0_YEAST
Sequence: MSLYPLQRFESNDTVFSYTLNSKTELFNESRNNDKQHFTLQLIPNANANAKEIDNNNVEIINDLTGNTIVDNCVTTATSSNQLERRLSISDYRTENGNYYEYEFFGRRELNEPLFNNDIVENDDDIDLNNESDVLMVSDDELEVNERFSFLKQQPLDGLNRISSTNNLKNLEIHEFIIDPTENIDDELEDSFTTVPQSKKKVRDYFKLNIFGSSSSSNNNSNSLGCEPIQTENSSSQKMFKNRFFRSRKSTLIKSLPLEQENEVLINSGFDVSSNEESDESDHAIINPLKLVGNNKDISTQSIAKTTNPFKSGSDFKMIEPVSKFSNDSRKDLLAAISEPSSSPSPSAPSPSVQSSSSSHGLVVRKKTGSMQKTRGRKPSLIPDASKQFGCEFCDRRFKRQEHLKRHVRSLHMCEKPFTCHICNKNFSRSDNLNQHVKTHASL
What are the official names of this protein?
Zinc finger protein YER130C.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABH_MYCMM
Sequence: MTEIATTSGISSVGLLSVGAYRPTRVVTNDEICENIDSSDEWIYSRTGIKTRRFAAPEESAASMAIEASREAIAKAALTGSDIDGVIVATSTHFLQTPACAPIVAAALGCQNVPAFDISAGCSGFGHALGIAADMIRGGSAATILVIGTEKLSPTVDMTDRSNCFIFADGAASVLVGHSPIQGIGPTVWGSDGEQAAAIRQDIDWISHAENPAGPRPFLRMEGTAVFRWAAFEMGKVGQQAMDAAGVKPDEIDVFIPHQANSRINELLTKNLQLRPDAVIANDIEHTGNTSAASIPLAMAELLATGAAKPGDLALLIGYGAGLSYAAQVVRMPNS
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Mycobacterial beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_CUPPJ
Sequence: MNAVTDLKQDYLVADISLAGWGRKEIAIAETEMPGLMAIRDEFAAAQPLKGARIAGSLHMTIQTAVLIETLKALGADVRWASCNIFSTQDHAAAAIAAGGTPVFAFKGESLKEYWDFTHRIFDWVDGGTPNMILDDGGDATLLLHLGAKAEKDASLIANPGSEEETFLFAAIKEKLAKDPSWYSRNLAAIRGVTEETTTGVHRLYQMAQKGDLKFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAIVAGYGDVGKGSAQALRALSAQVWVTEIDPICALQAAMEGYRVVTMDYAAEHGDIFVTCTGNYHVITHDHMARMKDQAIVCNIGHFDNEIDIASIEKYEWDEIKPQVDHVKFPDGKKIIILAKGRLVNLGCATGHPSYVMSSSFANQTIAQIELWQERDSGKYPVGVYTLPKHLDEKVARLQLRKLNAQLTELTEQQAAYIGVKKEGPYKADHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTAA_FLAJ1
Sequence: MKKENKSVIIWLLSGCVLLFLMVVVGGITRLTNSGLSMTDWHLVTDTFPPLTDAKWQAAFDEYKKFPEYQKINIHNDFQLSDYKFIYFWEWFHRFIGRIIGLVFFVPFVYFLAKKKLDTSTIKKCIVLLAMGAFQGFLGWFMVRSGLIDNPDVSHFRLSLHLTFAFITFAYTLWVALDLIYPERNINKILPLRNIARYALAALLIQIIYGGFVAGLNAGLIHNHWPLMSDGEFIHESVFIEQSSLIKNLIEGKSGVQFVHRTFAYAVVAVILFLFFKSKKYTLTRTQSNGINTLVVFVFIQFLLGVFTLLYSVPLALGLIHQIMAFFLLSAMTYTLHRLSK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SG2A1_HUMAN
Sequence: MKLLMVLMLAALLLHCYADSGCKLLEDMVEKTINSDISIPEYKELLQEFIDSDAAAEAMGKFKQCFLNQSHRTLKNFGLMMHTVYDSIWCNMKSN
What is the function of this protein?
May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer.  May be under transcriptional regulation of steroid hormones.
What are the official names of this protein?
Mammaglobin-B, Lacryglobin, Lipophilin-C, Mammaglobin-2, Secretoglobin family 2A member 1.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family. Lipophilin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: T10H_TAXCU
Sequence: MDSFIFLRSIGTKFGQLESSPAILSLTLAPILAIILLLLFRYNHRSSVKLPPGKLGFPLIGETIQLLRTLRSETPQKFFDDRLKKFGPVYMTSLIGHPTVVLCGPAGNKLVLSNEDKLVEMEGPKSFMKLIGEDSIVAKRGEDHRILRTALARFLGAQALQNYLGRMSSEIGHHFNEKWKGKDEVKVLPLVRGLIFSIASTLFFDVNDGHQQKQLHHLLETILVGSLSVPLDFPGTRYRKGLQARLKLDEILSSLIKRRRRDLRSGIASDDQDLLSVLLTFRDEKGNSLTDQGILDNFSAMFHASYDTTVAPMALIFKLLYSNPEYHEKVFQEQLEIIGNKKEGEEISWKDLKSMKYTWQAVQESLRMYPPVFGIFRKAITDIHYDGYTIPKGWRVLCSPYTTHLREEYFPEPEEFRPSRFEDEGRHVTPYTYVPFGGGLRTCPGWEFSKIEILLFVHHFVKNFSSYIPVDPNEKVLSDPLPPLPANGFSIKLFPRS
What is the function of this protein?
Involved in the transformation of a taxadienyl acetate by hydroxylation at C10 to yield taxadien-5-alpha-acetoxy-10-beta-ol.
What are the official names of this protein?
Taxane 10-beta-hydroxylase, 5-alpha-taxadienol-10-beta-hydroxylase, Cytochrome P450 725A1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RS18_MYCGE
Sequence: MMINKEQDLNQLETNQEQSVEQNQTDEKRKPKPNFKRAKKYCRFCAIGQLRIDFIDDLEAIKRFLSPYAKINPRRITGNCNMHQRHVANALKRARYLALVPFIKD
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TRM52_TRYCC
Sequence: MSGEERHQGGGEKGPMDHDEPPSYRTRVEASVELMALRVKPVHLLGEVLKALRGCLYDMRGVRNVMDAPQPTSDPGEEHKLLLLNPQVIPPPSSAAKNDSMAPTQPLWVEANHASVPPVVRERLQSFLLGKRSVAQSLRVAVAQHTVRLSHRNFTMPELLQRILPPGTIPLSGFEQVGHIAHVNLSAAHLPYRADIGAVILDCNPTVRVVVNKVDNIASVFREFKMEVIARRTTHSDMKGTPVKENSGDEEELHGLLLATVRQHGCIFRVPYDRVYWNSRLSHEHARVVGMMQSGDMLYDAMAGVGPFAIPAAVAGVKTYANDLNPVAAEYLRINAELNHINKDTFHVFNMDGREFLNTVLYRDVVSGAAVCGRRHVTMNLPAIAVEFLDVFTKPPWSQPLVSLSSLEEKAKEGKEKGEHVKMHPDKRLLFHVYCFSKNMDDFLGDAVKQVERWLAFSLAGENLEAVHMVRDVAPLKRMVCVSFTLPEAFWLHREAKGMSPLKRARSD
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase 2, M1G-methyltransferase 2, tRNA [GM37] methyltransferase 2, tRNA methyltransferase 5 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: COPA_BOVIN
Sequence: MLTKFETKSARVKGLSFHPKRPWILTSLHNGVIQLWDYRMCTLIDKFDEHDGPVRGIDFHKQQPLFVSGGDDYKIKVWNYKLRRCLFTLLGHLDYIRTTFFHHEYPWILSASDDQTIRVWNWQSRTCVCVLTGHNHYVMCAQFHPSEDLVVSASLDQTVRVWDISGLRKKNLSPGAVESDVRGITGVDLFGTTDAVVKHVLEGHDRGVNWAAFHPTMPLIVSGADDRQVKIWRMNESKAWEVDTCRGHYNNVSCAVFHPRQELILSNSEDKSIRVWDMSKRTGVQTFRRDHDRFWVLAAHPNLNLFAAGHDGGMIVFKLERERPAYAVHGNMLHYVKDRFLRQLDFNSSKDVAVMQLRSGSKFPVFSMSYNPAENAVLLCTRASNLENSTYDLYTIPKDADTQNPDAPEGKRSSGLTAVWVARNRFAVLDRMHSLLIKNLKNEITKKVQVPNCDEIFYAGTGNLLLRDAESITLFDVQQKRTLASVKISKVKYVIWSADMSHVALLAKHAIVICNRKLEALCNIHENIRVKSGAWDESGVFIYTTSNHIKYAVTTGDYGIIRTLDLPIYVTRVKGNNVYCLDRECRPRVLTIDPTEFKFKLALINRKYDEVLHMVRNAKLVGQSIIAYLQKKGYPEVALHFVKDEKTRFSLALECGNIEIALEAAKALDDKNCWEKLGEVALLQGNHQIVEMCYQRTKNFDKLSFLYLITGNLEKLRKMMKIAEIRKDMSGHYQNALYLGDVSERVRILKNCGQKSLAYLTAATHGLDEEAESLKETFDPEKETIPDIDPNAKLLQPPAPIMPLDTNWPLLTVSKGFFEGSIASKGKGGALAADIDIDTVGTEGWGEDAELQLDEDGFVEATEGLGDDALGKGQEEGGGWDVEEDLELPPELDIPPGAAGGAEDGFFVPPTKGTSPTQIWCNNSQLPVDHILAGSFETAMRLLHDQVGVTQFGPYKQLFLQTYARGRTTYQALPCLPSMYGYPNRNWKDAGLKNGVPAVGLKLNDLIQRLQLCYQLTTVGKFEEAVEKFRSILLSVPLLVVDNKQEIAEAQQLITICREYIVGLSMETERKKLPKETLEQQKRICEMAAYFTHSNLQPVHMILVLRTALNLFFKLKNFRTAAAFARRLLELGPKPEVAQQTRKILSACEKNPTDAYQLNYDMHNPFDICAASYRPIYRGKPVEKCPLSGACYSPEFKGQICKVTTVTEIGKDVIGLRISPLQFR
What is the function of this protein?
Xenin stimulates exocrine pancreatic secretion.  It inhibits pentagastrin-stimulated secretion of acid, to induce exocrine pancreatic secretion and to affect small and large intestinal motility.  In the gut, xenin interacts with the neurotensin receptor (By similarity).
What are the official names of this protein?
Coatomer subunit alpha, Alpha-coat protein, Alpha-COP, HEP-COP, HEPCOP.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. SUBCELLULAR LOCATION: [Xenin]: Secreted.
Protein: SYP_STAAN
Sequence: MKQSKVFIPTMRDVPSEAEAQSHRLLLKSGLIKQSTSGIYSYLPLATRVLNNITAIVRQEMERIDSVEILMPALQQAELWEESGRWGAYGPELMRLQDRHGRQFALGPTHEELVTSIVRNELKSYKQLPMTLFQIQSKFRDEKRPRFGLLRGREFIMKDAYSFHADEASLDQTYQDMYQAYSRIFERVGINARPVVADSGAIGGSHTHEFMALSAIGEDTIVYSKESDYAANIEKAEVVYEPNHKHSTVQPLEKIETPNVKTAQELADFLGRPVDEIVKTMIFKVDGEYIMVLVRGHHEINDIKLKSYFGTDNIELATQDEIVNLVGANPGSLGPVIDKEIKIYADNFVQDLNNLVVGANEDGYHLINVNVGRDFNVDEYGDFRFILEGEKLSDGSGVAHFAEGIEVGQVFKLGTKYSESMNATFLDNQGKAQPLIMGCYGIGISRTLSAIVEQNHDDNGIVWPKSVTPFDLHLISINPKKDDQRELADALYAEFNTKFDVLYDDRQERAGVKFNDADLIGLPLRIVVGKRASEGIVEVKERLTGDSEEVHIDDLMTVITNKYDNLK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOMPL_CHLTH
Sequence: MKKLLKSVLVFAALSSASSLQALPVGNPAEPSLMIDGILWEGFGGDPCDPCTTWCDAISMRMGYYGDFVFDRVLQTDVNKEFQMGAKPTATTGNAAAPSTCTARENPAYGRHMQDAEMFTNAAYMALNIWDRFDVFCTLGATSGYLKGNSASFNLVGLFGDNENQSTVKKDAVPNMSFDQSVVELYTDTTFAWSVGARAALWECGCATLGASFQYAQSKPKVEELNVLCNAAEFTINKPKGYVGKEFPLDLTAGTDAATGTKDASIDYHEWQASLALSYRLNMFTPYIGVKWSRASFDADTIRIAQPKLATAIFDTTTLNPTIAGAGEVKANAEGQLGDTMQIVSLQLNKMKSRKSCGIAVGTTIVDADKYAVTVETRLIDERAAHVNAQFRF
What is the function of this protein?
Permits diffusion of specific solutes through the outer membrane.
What are the official names of this protein?
Major outer membrane porin, serovar L1, MOMP.
What is the protein family that this protein belongs to?
Belongs to the chlamydial porin (CP) (TC 1.B.2) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: GPMI_ALIF1
Sequence: MSAKKPMALVILDGYGHRETQADNAITNANTPVLDGLMANQPNTLISASGMDVGLPDGQMGNSEVGHTNIGAGRVVYQDLTRITKAISDGEFQQNETLVNAIDKAVKAGKAVHIMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRSAENSLKNFQELFAKLGKGRIASLVGRYYAMDRDNNWERVQKAYDLMTEAKAEFTFATAVEGLEAAYAREENDEFVQATEIKAEGEESAAIVDGDAVIFMNYRADRARQITRTFVPSFDGFTRNVFPAIDFVMLTQYAADIPLLCAFAPASLENTYGEWLSKEGKTQLRISETEKYAHVTFFFNGGIEDEFEGEERQLVASPKVATYDLQPEMSAPELTEKLVAAIKSGKYDAIVCNFPNCDMVGHTGVYDAAVKAVESLDECIGKVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTNLPVPLIYVGSKAVEFKEGGKLSDLAPTMLALTDTAIPAEMSGEVLFK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: UVRB_STRT2
Sequence: MKGKTMIDRKEDNQFHLVSKYEPSGDQPQAIETLVDNIKGGEKAQILKGATGTGKTYTMSQVIQRVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSINDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYADSAVSLRPGQEISRDKLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDENAFRVEFFGDEIDRICEIESLTGRNLGEVEHLVLFPATHFMTNEEHMEEAIKNIMEEMEVQVNQFEAEGKLIEAQRIRQRTEYDVEMLREMGYTNGIENYSRHMDGRKEGEPPFTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKKMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYEMEQTETVVEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINARTEKGERVFVTTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSDGHVIMYADKITESMQKAMDETARRREIQMAYNKEHGITPQTIKKEIRDLISITKTNEAEVAEDTVNYSAMNKKERQEAIKKLQKQMHEAAELLDFELAAQIRDMVLELKSMD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_STAA2
Sequence: MAKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIRGQINKVKHLVTVEEK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PUR9_PSEAE
Sequence: MTDQTTRLPIRRALISVSDKTGVVDFARELVALGVEILSTGGTYKLLRDNGISAVEVADYTGFPEMMDGRVKTLHPKVHGGILGRRDLDGAVMEQHGIKPIDLVAVNLYPFEATVARPDCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNAGDYAAVIESLKAGGLTYAQRFDLALKAFEHTSAYDGMIANYLGTIDQTRDTLGTADRGAFPRTFNSQFVKAQEMRYGENPHQSAAFYVEAKKGEASVSTAIQLQGKELSFNNVADTDAALECVKSFLKPACVIVKHANPCGVAVVPEDEGGIRKAYDLAYATDSESAFGGIIAFNRELDGETAKAIVERQFVEVIIAPKISAAAREVVAAKANVRLLECGEWPAERAPGWDFKRVNGGLLVQSRDIGMIKAEDLKIVTRRAPTEQEIHDLIFAWKVAKFVKSNAIVYARNRQTVGVGAGQMSRVNSARIAAIKAEHAGLEVKGAVMASDAFFPFRDGIDNAAKAGITAVIQPGGSMRDNEVIAAADEADIAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: BIOC_ECOLI
Sequence: MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRKYTHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPKGVVAFTTLVQGSLPELHQAWQAVDERPHANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRILTRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.  E. coli employs a methylation and demethylation strategy to allow elongation of a temporarily disguised malonate moiety to a pimelate moiety by the fatty acid synthetic enzymes.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: HIS8_METVS
Sequence: MTIDDIIRPIVKEFKAYVPGKSKEEIARNYGISIEKIIKLGSNENPWGCSPKIKEALLLELSKLHQYPEPLNSELLGEISSFIGVPCENIIIGGDGADEVIDNIMRILIDEGDEVIIPIPTFTQYAISAKIHGAKIKWAKFDKEKDFKLDVESVLNNITEKTKAIFLCTPNNPTGNVISNEDIKKIIESTDALIMIDHAYIEYSKKEYDLTQWALKYDNVLVLRTFSKVFGLAGQRIGYGVTNKKIVDYMMRIKPIFSLTRASQVSAITALKDKEFFNGCKINGIRSITQLHDGLKKFKQLKVYPTETNYLLVEIKNGMNSKEFCEILLKKGVIVRDCYSFEGLEPYYFRVSIGTFEENERFLEIMSEIIE
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: TRPC_DEHMC
Sequence: MILERIVTDNLPDLERRKMRLPLAKLQELVLDIPYPPIDMAMKLKGRQVRLIAEVKKASPSKGIIRSDFDPVDIAGIYARNGASAISVLTEEHHFMGSLDNLKKIRESGVASKLPLLRKDFIHDPYQVYESRLYGADAILLIVAMLSPERLQELLSLSHKLGMKCLVEVHTRSELEIALESNARIIGLNNRDLHTFKIDLTVTERLRPLIPPECIVVSESGIQTRADISRLEELGVDAVLVGEALTASVDIAAKMRELL
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RS27_CHLRE
Sequence: MVLSSDIDLLNPPAELEKTKHKRKRLVQSPNSFFMDVKCQGCFNITTVFSHSQTVVMCGSCSSVLCTPTGWPRRLTEGCSFRRKSD
What are the official names of this protein?
40S ribosomal protein S27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: PTWCB_BACSU
Sequence: MLSFLQKLGKSFMLPIAVLPAVGIILALGREDVFNIPFVYQAGTAVFDHLPLIFAIGIAIGISKDSNGAAGLSGAISYLMLDAATKTIDKTNNMAVFGGIIAGLIAGYTYNRFKDTKLPEYLGFFSGRRLVPILTAIITIILAGIFGVVWPPIQSCINSFGEWMLGLGGIGAGIFGLFNRLLIPLGLHHVLNNIFWFQFGEYNGVTGDLARFFAKDPTAGTYMTGFFPIMMFGLPAACLAMVVTAKPSKRKATAGMMIGFALTAFITGITEPIEFAFMFLSPLLYAVHAVLTGLSLFIVNWLGIRSGFSFSAGAIDYVLSYGIAEKPLLLLLVGICYAAVYFIVFYVLIKALNLKTPGREDDDVDEVLDENTVQDVNENIMLKGLGGKENLQTIDHCATRLRLTVKDTALVDEALLKKAGAKGVVKSGGQSVQVIIGPNVEFAAEELRAAVK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  This system is involved in N-acetylglucosamine transport (By similarity).
What are the official names of this protein?
PTS system N-acetylglucosamine-specific EIICB component, EIICB-Nag.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: PRIB_NEIM0
Sequence: MGFNNLVSLAALIEKVFPIRYTPAGISVLDIILKHESWQKENGQQCFVQLEIPARILGRQAEEWQYRQGVYVHVEGFLAQKSRRSLMPMLRIQNIKEYKG
What is the function of this protein?
Stimulates the DNA unwinding activity of PriA helicase, which does not seem to require single-stranded DNA-binding by PriB.  Activates DNA-dependent ATP hydrolysis catalyzed by PriA.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.