PharMolix/UniProtQA huggingface dataset:
Protein: RS20_FINM2
Sequence: MANIKSAIKRIDVTKLETARNKSKKSAIKTFIKKFEAAIEKNDKEDATKLFNLATKKIDQAASKNTISKNSAAKKISRMAKELNKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PAR1_RAT
Sequence: MGPRRLLLVAVGLSLCGPLLSSRVPMRQPESERMYATPYATPNPRSFFLRNPSEDTFEQFPLGDEEEKNESIPLEGRAVYLNKSRFPPMPPPPFISEDASGYLTSPWLTLFIPSVYTFVFIVSLPLNILAIAVFVFRMKVKKPAVVYMLHLAMADVLFVSVLPFKISYYFSGTDWQFGSGMCRFATAACYCNMYASIMLMTVISIDRFLAVVYPIQSLSWRTLGRANFTCVVIWVMAIMGVVPLLLKEQTTQVPGLNITTCHDVLNETLLHGFYSYYFSAFSAIFFLVPLIISTVCYTSIIRCLSSSAVANRSKKSRALFLSAAVFCIFIVCFGPTNVLLIVHYLLLSDSPGTETAYFAYLLCVCVTSVASCIDPLIYYYASSECQKHLYSILCCRESSDSNSCNSTGQLMPSKMDTCSSHLNNSIYKKLLA
What is the function of this protein?
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
What are the official names of this protein?
Proteinase-activated receptor 1, PAR-1, Thrombin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS17_BUCCC
Sequence: MNEKKNLLNGYIVSNKMNKSAVVIVERKIKHSIYKKFIKKRTKLCIHDEKNICNIGDIVTIRECRPISKTKSWILVNILEKSIV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: TIG_HAHCH
Sequence: MQVSLESTSSIERRMTIGVPATQVNSEVEKRLQKTARTVRMNGFRPGKVPMSVVKKRYGEGVRQEVIGEMMRDAYVEALQKEDLNPAGYPKFEPKKIEDGEDLEFIATFEIYPEVSIGDLSSISVEKEDFEIVDADVDSMIEKLRQQSSEWKDSEDAAAEGDRLTIDFKGMIDGEAFEGGSAQNAQIVIGSQRMIPGFEDGLVGLKAGDEKTLDLTFPEDYHAENLKGKLAQFEVKVSKVERSELPEINDEFFAQYGVQEGGEEAFKVEIRKNMEREARFAIANKVKQQVVDQLLGLSEFEVPSALVDSEVNRMREDAVQRFGGGQMKASQLPAELFKDQAVKRVKTGLIFAQVVKDNNLEATEEQIEAKIRELASSYQEPEQVVSWYMSNPEQKAQMQSVVLEDVVVDFVADKAKIETKSVSYEDAVKPRTAPAEQAEDGEQSAE
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: CSBL2_DICDI
Sequence: MTEKMHELKITIFTDKGRSTISGIDFPLPVLPYPAPYTFRLYGYKIEGPNLTNKEFKVKTGKIEYKGEEFDIPPSSKGSWRGVDEEMDLTYVTIYPSRQPKKVFHY
What are the official names of this protein?
Uncharacterized protein csb family protein DDB_G0271320.
What is the protein family that this protein belongs to?
Belongs to the csb family.
Protein: ILVC_PARPJ
Sequence: MKVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKESGVNITVGLRKGGASWSKAENAGLQVKEVAEAVKGADVVMMLLPDEQIAEVYAKEVHANIKQGAALAFAHGFNVHYGQVIPRADLDVIMIAPKAPGHTVRGTYSQGGGVPHLIAVAQDKSGAARDIALSYAAANGGGRAGIIETNFREETETDLFGEQAVLCGGTVDLIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRIVTAETKKAMKAVLTDIQTGEYAKSFIIENKAGAPTLQSRRRLTAEHQIETVGAKLRSMMPWIAANKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: EF2_RABIT
Sequence: MVNFTVDQISAIMDKKANISNMSVIARVDDGKSTL
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Phosphorylation by CSK promotes cleavage and SUMOylation-dependent nuclear translocation of the C- terminal cleavage product.
Protein: MURD_BACLD
Sequence: MDTQDLLQNQNVLVLGLAKSGYAAASILHEKGVKVVVNDQLPFEENEPARILAEKGVEVVCGSHPTELFDLHSIDILIKNPGIRYENVMVEEALKRGIPVWTEVELAYHLTDAPFIGITGSNGKTTTTTLVYEMLKADSKKALVAGNIGTAASEVANQASGDEWIVTELSSFQLMGTYQFRPKIGLLLNVFDAHLDYHHSRKNYELAKQQVYRNQSETDVAVVNLDDETVVRLAECSKAEKVYFSVRRTLERGACVKDGAIMFNGEPVMPLEDVVLPGEHNLENILAALCIVKTAGVSDAAVRKVLTSFTGVKHRMQYVATIKNRLFYNDSKATNILATKKALSAFQKPVILLAGGLDRGNEFDELKPHMSFVKAVITFGETAPKFEKLAEEMGIQQVKRVDNVEQAATAAFSLSDEGDVILLSPACASWDQYKTFEERGDMFVNAVHMLK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_COTJA
Sequence: MANHSQLGFQDASSPIMEELVEFHDHALMVALAICSLVLYLLTLMLTQKLSSNTVDAQEVELIWTILPAIVLVLLALPSLQILYMMDEIEEPDLTLKAIGHQWYWSYEYTDFKDLSFDSYMTPTTDLPQGHFRLLEVDHRIVIPMESPIRIIITADDVLHSWAVPTLGVKTDAIPGRLNQTSFITTRPGVFYGQCSEICGANHSYMPIVVESTPLKHFETWSSLLSS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NADE_COREF
Sequence: MTDTRDHIISQLSVVPSIEPAAEVEARVQFLVDYLRVSHARGYVLGISGGQDSTIAGRLAQLAVERIRREDGSDHQFVGVRLPHGLQADEDDALVALDFIQPDRSISINIREATDVLSAATAAALGIDELGDFNKGNVKARQRMVAQYAIAGELGLLVVGTDHAAENVTGFFTKYGDGAADVLPLAGLTKRQGALLLQHLGAPESTWTKVPTADLEEDRPALPDEEALGVTYREIDTYLENSGEVSPEAAARIEHLWKVGQHKRHMPVTPQDQWWRQ
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: YGB4_CUPNE
Sequence: MPRFAANLSMMYNEHAFLDRFAAAAADGFRAVEFLFPYEHAAAELRARLDANGLTQALFNAAPGDWAAGERGLAALPGREADFRGTIGRALEYAGVIGNDRIHVMAGLIPADADRARCRATYLENLAFAANAAAAQGVTVLIEPINTRDMPGYFLNRQDDGQAICKEVGAANLKVQFDCYHCQIVEGDVAMKLKRDIAGIGHIQIAGVPERHEPDVGELNYPYLFEVMDTLGYDGWIGCEYRPRAGTSAGLGWLKPYLGR
What is the function of this protein?
Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).
What are the official names of this protein?
Putative hydroxypyruvate isomerase, Glyoxylate-induced protein.
What is the protein family that this protein belongs to?
Belongs to the hyi family.
Protein: GPR63_HUMAN
Sequence: MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV
What is the function of this protein?
Orphan receptor.  May play a role in brain function.
What are the official names of this protein?
Probable G-protein coupled receptor 63, PSP24-2, PSP24-beta.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HLDE_ACICJ
Sequence: MAEHDDGDLIAAIRGLARANVLVVGDLMLDRYAYGRVERISPEAPVPILTVTREIAMPGGAGNVVRNLTALDAAAAFVSVVGDDQEGSDLTALIGGQPNVEPWLLVETGRATTVKTRYIAAGQHLIRADRELVMPLTDKLGERLLKIASDAMAATSVTVLSDYRKGVLAPTIARNLIASARSIGRTVIVDPKGADWSHYAEADVITPNRRELAEAVGRDLPDEAAIVGAAREVIGRFGFGAVLCTRSEDGMSLVTVDTVRHYPAEAAEVYDVSGAGDTVVAVLAAGLASGLPLEIAARLSNIAGGLVVGKVGTAVARPDDLVDAVKPASGALRKVVTRQAAAEAAERWRQRGWRIGFTNGCFDLLHPGHVHLLEQARAGCDRLVVGLNADSSVRRLKGATRPVQPEAARAAVLASLASVDLVVIFEEDTPLDLLSAIRPDVLVKGADYTHDTVVGAREVESWGGRVMLAELLPGHSTTATVTRLRS
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: PEPA_RHIFE
Sequence: MKWLLLLSLVALSECYIYKVPLVKKKSLRKNLMEQGLLQDYLKTHSINPASKYLKEAASMMATQPLENYMDMEYFGTIGIGTPPQEFTVIFDTGSSNLWVPSVYCSSPACSNHNRFNPQQSSTYQGTNQKLSVAYGTGSMTGILGYDTVQVGGITDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSIASSGATPVFDNIWNQGLVSQDLFSVYLSSNDQGGSVVMFGGIDSSYFTGNLNWVPLSSETYWQITVDSITMNGQVIACSGSCQAIVDTGTSLLSGPTNAIASIQGYIGASQNANGEMVVSCSAINTLPNIVFTINGVQYPLPPSAYVLQSQQGCTSGFQGMDIPTSSGELWILGDVFIRQYFTVFDRGNNQVGLAPVA
What is the function of this protein?
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
What are the official names of this protein?
Pepsin A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AT1A_ARTSF
Sequence: MGKKQGKQLSDLKKELELDQHKIPLEELCRRLGTNTETGLTSSQAKSHLEKYGPNALTPPRTTPEWIKFCKQLFGGFQMLLWIGSILCFIAYTMEKYKNPDVLGDNLYLGLALLFVVIMTGCFAYYQDHNASKIMDSFKNLMPQFAFVIRDGKKIQLKAEEVTVGDLVEVKFGDRIPADIRITSCQSMKVDNSSLTGESEPQSRSTECTNDNPLETKNLAFFFTNTLEGTGRGIVINVGDDSVMGRIACLASSLDSGKTPIAREIEHFIHIITAMAVSLAAVFAVISFLYGYTWLEAAIFMIGIIVAKVPEGLLATVTVCLTLTAKRMAKKNCLVRNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDQKIVTADTTENQSGNQLYRGSKGFPELIRVASLCSRAEFKTEHAHLPVLKRDVNGDASEAAILKFAEMSTGSVMNIRSKQKKVSEIPFNSANKYQVSVHEREDKSGYFLVMKGAPERILERCSTILIDGTEIPLDNHMKECFNNAYMELGGMGERVLGFCDFELPSDQYPRGYVFDADEPNFPISGLRFVGLMSMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIARQVGIISEGHETVDDIAARLNIPVSEVNPRSAQAAVIHGNDLKDMNSDQLDDILRHYREIVFARTSPQQKLIIVEGVQRQGEFVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNIKKSIAYTLTSKIPELSPFLMYILFDLPLAIGTVTILCIDLGTDVVPAISMAYEGPEADPRKPRDPVKEKLVNERLISMAYGQIGVMQAFGGFFTYFVIMGECGFLPNRLFGLRKWWESKAYNDLTDSYGQEWTWDARKQLEYTCHTAFFISIVIVQWTDLIICKTRRLSLFQQGMKNGTLNFALVFETCVAAFLSYTPGMDKGLRMYPLKIWWWFPPMPFSLLILVYDECRKFLMRRNPGGFLERETYY
What is the function of this protein?
This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane.  This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit alpha-A, Na(+)/K(+) ATPase alpha-A subunit, Sodium pump subunit alpha-A.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2225_RHILO
Sequence: MWNGIIPGLVLVAMITAVAFSAHNVSGFALFSPMILAVVAGMVYSNVLGTPAHAKAGIAFSQKRLLRFAIVLLGFQLTLGQVVSIGAGGVGIVAATLGATFVFTITLGRLIGVDRKLAQLIAAGTSICGASAIVATNIVTDARDEDVTYAVASITLFGTVAMLGFPLLAPALGLDQHAFGLWAGASIHEVAQVIGAGFQNGTQSGEIATVAKLTRVTMLAPMVIALGLMARRKTSGGQQAARPPMPWFVAAFVAVVALNSLVTVPAEVKSAMALATTIMLTMGLAAMGLQADISQLRSRGLRPLALAFCAFLFIGCFSLVLVKFV
What are the official names of this protein?
UPF0324 membrane protein mlr2225.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR14_BUXMI
Sequence: MARKSLIQREKKRKKLEQKYHLIRRSSKKEISKVPSLSDKWEIHGKLQSPPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1098_ALTMD
Sequence: MFKGGMGNIMKQAQQMQERMQKVQDDLANLEVTGEAGAGMVKVTMTCNHNVRRVNIDESLMDDDKDMVEDLVAAAFNDAVRRVQETSKEKMGDVTGGMPLPPGFKMPGF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein MADE_1013280.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RPOA_CAMHC
Sequence: MRKITTSAYMPTEIEVENVSENVAKIIAYPFETGYAVTLAHPLRRLLYTSTVGYAPTAVKIDGVSHEFDSMRGMLEDVAIFIINLKGIRFKIKGDSKREVIEYNFTGPKEITGKDLNNDIVEIVNPDAYLATINEDADLKFSVVIEKGIGYVPSESIRDYVSSDYIALDAFFTPVIRAIYDIENVFVEDNPDYEKIIFTITTDGQVSAVDAFKNALEAMYQQMSVFKGIVDIDTGKSFTKQIPSGEHSKLFESIENLNLSARSFNCLEKADIKFVGEIVIMDESELKGIKNLGKKSLEEIKSVMEEIGYPIGNEEIKDKKEVLSKKIAELKKKAKDDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: BRM1L_XENLA
Sequence: MPVHSREKKESNHNDMEVDYPENEGSSSEEDDSDSSSGSEEGDSSEMDDEDCERRRMECLDEMSTLEKQFTDLKDQLYKERLSQVDAKLQEVKADQAQEYLEPLANLQENMQIRTKVAGIYRELCLESVKNKHDCEIQAARQHCESEKLLLYDTVQSELEEKIRRLEEDRHSIDITSELWNDELQSRRKRKDPFSPDKKKKPVVVSGPYIVYMLQDLDILEDWTTIRKAMASFGPHRVKPEVTVKIEKHQHSARSEEGRLHYDGEWYGRGQTICIDKKDEFPTSAVITTINSDEVWFKRQDGSKSKLYISQLQKGKYSIKHI
What is the function of this protein?
Involved in the histone deacetylase (HDAC1)-dependent transcriptional repression activity.
What are the official names of this protein?
Breast cancer metastasis-suppressor 1-like protein.
What is the protein family that this protein belongs to?
Belongs to the BRMS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1845_ARCFU
Sequence: MKFEFRTLVLISLAVVVVLSGCSQSPSSGGVPEYSGSKVYSAPTLYSQLIGVPTEGVSVKAYTVENANAKDILSWYKEKLSDYEIVNEMSVVQMTTPQGSAEWGAILFKKGDKGVGIWAMSGSGVEGGGAVYFIVEGPIDKLTGESGEAGGAGEQLPASDQASGEEPVKRYPGSVMLSYYKDTSNPLEVSIGIDYGTEDSAEKVAHWYKQELQAEGWVLESESSDDSSIDLAFSRGKEYIDIYIIEPYEGFLTRKLTSTTGRRGCHLTTWSVERSRWRGIPAQLCWNT
What are the official names of this protein?
Uncharacterized protein AF_1845.
Protein: FKRP_MOUSE
Sequence: MRLTRCWAALAAAIILNLLVFFYVSWLQHQPRNSRARGPRRTSAIGPRVTVLIREFEAFDNAVPELVDSFLQQDPAQPVVVAADTLPYPPLALPRIPNVRLALLQPALDRPAAASRPETYVATEFVALVPDGARAESPGHLERMVEALRGSSARLVAAPVATANPARCLALNVSLREWTARYDPAPSAPRCDALDGDAVLLMRSRDLFNLSVPLARPLATSLFLQTALRGWAVQLLDLTFAAARQPPLATAHARWKAEREGRSRRAALLRSLGIRLVSWEGGRLEWFGCSKESARCFGTVAGDTPAYLYEGRWTPPCCLRALRETARYVVGVLEAAGVRYWLEGGSLLGAARHGDIIPWDYDVDLGIYLEDVGNCEQLRGAEAGSVVDERGFVWEKAVEGDFFRVQYSENNHLHVDLWPFYPRNGVMTKDTWLDHRQDVEFPEHFLQPLVPLPFAGFMAQAPNNYRRFLELKFGPGVIENPEYPNPALLSLTGG
What is the function of this protein?
Catalyzes the transfer of CDP-ribitol to ribitol 5-phosphate previously attached by FKTN/fukutin of to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1) (PubMed:26923585).  This constitutes the second step in the formation of the ribose 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha-1,3-glucuronic acid-beta-1 (PubMed:26923585).
What are the official names of this protein?
Ribitol 5-phosphate transferase FKRP, Fukutin-related protein, Ribitol-5-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the LicD transferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Cell membrane, sarcolemma. Rough endoplasmic reticulum. Cytoplasm. Note=The N-terminal hydrophobic domain is cleaved after translocation to the Golgi apparatus and the protein is secreted (PubMed:19900540). Localization at the cell membrane may require the presence of dystroglycan (PubMed:17452335). At the Golgi apparatus localizes to the middle-to-trans-cisternae (PubMed:12471058, PubMed:17554798). Detected in rough endoplasmic reticulum in myocytes (By similarity).
Protein: GATA2_CLOAB
Sequence: MEILDMTVEQLRNAILDKHLKSEDIVKAYFDNIKRNEPEINAYITLCEDYALKEAKDVDKKIANGDKVGRLAGIPIAIKDNICTDGIKTTCASKMLYDFVPPYDATVIKKLKAEDAIIIGKVNMDEFAMGSSTENSAFKITKNPRDITRVPGGSSGGSAAVVAAKMAPISLGSDTGGSIRQPAAFCGVVGLKPTYGLVSRFGLIAFASSLDQIGPLGKTVKDCAELLEVISGEDELDNTSSKKHEKEDYLEGIDDGIKGMKIGMPKEFLNDGLDPEIRKCIDDTIEKLKSLGAEVCEMSLPITEEGLSAYYIISSAEASSNLARFDGIRYGYRPDDFEDVYDLMETSRSEAFGDEVKRRIMLGTYALSSGYYDAYYKRALKLKKKIKNEFKEAFENYDLILSPVSPVLPFKIGEKKADPLQMYLADIYTVNINLAGIPAISLPCSVSKEGLPIGLQLLGPHFGEKKIFRAARALEKER
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A 2, Glu-ADT subunit A 2.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SELM_DANRE
Sequence: MWPLIFTALLPSVILTYEVNIEKLSGLARARVETCGGUQLNRMREVKAFVTQDIPLYHNLVMKHIPGADPELVLLNHYYEELDRIPLSEMTRAEINKLLAELGFYKKGHPEDQVPEEFRFSPAKDSPFESRLSSAAAPETTEPSDSQHTDL
What is the function of this protein?
May function as a thiol-disulfide oxidoreductase that participates in disulfide bond formation.
What are the official names of this protein?
Selenoprotein M, SePM, SelM.
What is the protein family that this protein belongs to?
Belongs to the selenoprotein M/F family.
Protein: NMD3A_RAT
Sequence: MRRLSLWWLLSRVCLLLPPPCALVLAGVPSSSSHPQPCQILKRIGHAVRVGAVHLQPWTTAPRAASRAQEGGRAGAQRDDPESGTWRPPAPSQGARWLGSALHGRGPPGSRKLGEGAGAETLWPRDALLFAVENLNRVEGLLPYNLSLEVVMAIEAGLGDLPLMPFSSPSSPWSSDPFSFLQSVCHTVVVQGVSALLAFPQSQGEMMELDLVSSVLHIPVLSIVRHEFPRESQNPLHLQLSLENSLSSDADVTVSILTMNNWYNFSLLLCQEDWNITDFLLLTENNSKFHLESVINITANLSSTKDLLSFLQVQMDNIRNSTPTMVMFGCDMDSIRQIFEMSTQFGLSPPELHWVLGDSQNVEELRTEGLPLGLIAHGKTTQSVFEYYVQDAMELVARAVATATMIQPELALLPSTMNCMDVKTTNLTSGQYLSRFLANTTFRGLSGSIKVKGSTIISSENNFFIWNLQHDPMGKPMWTRLGSWQGGRIVMDSGIWPEQAQRHKTHFQHPNKLHLRVVTLIEHPFVFTREVDDEGLCPAGQLCLDPMTNDSSMLDRLFSSLHSSNDTVPIKFKKCCYGYCIDLLEQLAEDMNFDFDLYIVGDGKYGAWKNGHWTGLVGDLLSGTANMAVTSFSINTARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAFMWPLHWTMWLGIFVALHITAIFLTLYEWKSPFGMTPKGRNRNKVFSFSSALNVCYALLFGRTAAIKPPKCWTGRFLMNLWAIFCMFCLSTYTANLAAVMVGEKIYEELSGIHDPKLHHPSQGFRFGTVRESSAEDYVRQSFPEMHEYMRRYNVPATPDGVQYLKNDPEKLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPPNSPLTSNISELISQYKSHGFMDVLHDKWYKVVPCGKRSFAVTETLQMGIKHFSGLFVLLCIGFGLSILTTIGEHIVHRLLLPRIKNKSKLQYWLHTSQRFHRALNTSFVEEKQPRSKTKRVEKSRWRRWTCKTEGDSELSLFPRSNLGPQQLMVWNTSNLSHDNQRKYIFNDEEGQNQLGTQAHQDIPLPQRRRELPASLTTNGKADSLNVTRSSVIQELSELEKQIQVIRQELQLAVSRKTELEEYQKTNRTCES
What is the function of this protein?
NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium.  Mediated by glycine.  During the development of neural circuits, plays a role in the synaptic refinement period, restricting spine maturation and growth.  By competing with GIT1 interaction with ARHGEF7/beta-PIX, may reduce GIT1/ARHGEF7-regulated local activation of RAC1, hence affecting signaling and limiting the maturation and growth of inactive synapses (PubMed:25009255, PubMed:24297929).  May also play a role in PPP2CB-NMDAR mediated signaling mechanism.
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 3A, GluN3A, Glutamate receptor chi-1, N-methyl-D-aspartate receptor, N-methyl-D-aspartate receptor subtype 3A, NMDAR3A, NR3A, NMDAR-L, NMDAR-L1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR3A/GRIN3A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. Requires the presence of GRIN1 to be targeted at the plasma membrane.
Protein: RLA2_BABBO
Sequence: MALKYVSSYLLAVAAGNENPSVDDLKKILDAVGSDVDEECLQGLVDSMSGKTVHETIAAGMTKLQSMPAGGAAMPAAAAGGAPAAAEDKAEAKKPEAEPEEEEDDMGFSLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2, L12EI.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.