PharMolix/UniProtQA huggingface dataset:
Protein: DORS_DROME
Sequence: MFPNQNNGAAPGQGPAVDGQQSLNYNGLPAQQQQQLAQSTKNVRKKPYVKITEQPAGKALRFRYECEGRSAGSIPGVNSTPENKTYPTIEIVGYKGRAVVVVSCVTKDTPYRPHPHNLVGKEGCKKGVCTLEINSETMRAVFSNLGIQCVKKKDIEAALKAREEIRVDPFKTGFSHRFQPSSIDLNSVRLCFQVFMESEQKGRFTSPLPPVVSEPIFDKKAMSDLVICRLCSCSATVFGNTQIILLCEKVAKEDISVRFFEEKNGQSVWEAFGDFQHTDVHKQTAITFKTPRYHTLDITEPAKVFIQLRRPSDGVTSEALPFEYVPMDSGKHTFWNLHRHLKRKPDEDLFQQILRLDAKREVQPPTIEVIDLDTPKIDVQREIPSEMEFNHEESQQSEPALEQEQSVQQEQYTQEQSLQQEQYTQEQSLQQEQYLQQLEQQQSFQLEEPMQQDQELPAQQSFDQAIDHLPDHTSDHIPEDMEAADAHAEAEAHRLRSEQEKEIDTIIDEKVRELEQLDLGQQLEPRPLTANDKITEWMKSSEIEQQVHEPSPTAEADVLDSALEISKADKTLDELLETVAELDEIYTDFKVQRDTYKNTIQNELAGLQGRAPLQVEDSFDDAATYTSLQIAFKNPVLIPMDDIMPPTPPMSQCAPEDAHQHYDPVEVNSQARKPETPMRPVPPVPPAILTIQYPPEEDKLPPLPPKRIRKQDSNAENRSIEANTVQTKPSTGESPLNKRLPPAPKNPNFNTLPRQKKPGFFSKLFSRRKSKPDLAQGQENSSILDSKANSREPSIGHFNMQDPMRASLRSSKSAAPFISNPAPAKSSPVKAKKPGSKLTKPVGRSVSSVSGKRPAYLNADVVHIPLKGDSVNSLPQQQRTEGYSQSSTISVGAGLDRRTASALQLADIPISEGGMELVAIADRQSLHNLVSSIEGHFNVQLDPNLDLTEAEHFALYTSIPPLAAASEFDETSAYYAPVDAGEILTPDEVAKRLAAANGI
What is the function of this protein?
Embryonic developmental protein (PubMed:2598266, PubMed:10072776).  The lateral or ventral identity of a cell depends upon the concentration of this protein in its nucleus during the blastoderm stage (PubMed:2598266).  A morphogenetic protein that specifically binds to the kappa B-related consensus sequence 5'-GRGAAAANCC-3', located in the enhancer region of zygotic genes such as Zen, Twist, Snail and Decapentaplegic.  Mediates an immune response in larvae (PubMed:10072776).  Part of a signaling pathway involving NF-kappa-B and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition (PubMed:25477468).  May be part of a NF-kappa-B and Tollo signaling cascade that regulates development of the peripheral nervous system (PubMed:18000549).
What are the official names of this protein?
Embryonic polarity protein dorsal.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In ventral regions it is first cytoplasmic, then the protein is relocalized in the nucleus (PubMed:2598266). Its nuclear localization is essential to its function as a morphogen (PubMed:2598266). In dorsal regions it remains cytoplasmic (PubMed:2598266). Tamo negatively regulates nuclear import of dl (PubMed:12653959). Emb is responsible for export of dl from the nucleus (PubMed:14638854). Nuclear localization is enhanced upon microbial infection (PubMed:17032737). SUBCELLULAR LOCATION: [Isoform A]: Nucleus.
Protein: PLYC_NEOFI
Sequence: MKLSAPLLVSLAAFSQAVTALVAFPGAEGFGADAIGGRKGQVYVVTNLNDSGTGSLRDAVSATDRIVVFAVGGVIKISERIVVSKRVTILGQTAPGDGITVYGNGWSFSNADDAIVRYIRIRMGKGGSSGKDAMGIAEGNRMIFDHVSVSWGRDETFSINGDASNITVQNSIIAQGLETHSCGGLIQTDGGVSLFRNLYIDNKTRNPKVKGVNEFTNNVVYNWGGGGGYIAGDSDGQSYANIIGNYFISGPSTSVTAFTRGNANFHGYVDNNYYDPDKDGQLDGSELGVSSSNYGGMAIVSSKYNYPAVAYTMSPAEAVTYVTKYAGASKVRDSVDTQLIAQVQSWGTKGALISDEATMGGPGTLNGGTPAKDTDGDGIPDEAEKQLGTDPNTNDSMKLHSSGYTYLEVWANSLVPSTYH
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase C.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: F215A_HUMAN
Sequence: MVSLWVEGTFPPPGFGLAHVACSGHGMKQKRKPASSEPTPEDALGGSAVPVRFHLHPEGLLWCSRCFFSHGPKGSEPPGRSAGLQGATERSGRPSVQAQAQACENLVPATVWDG
What are the official names of this protein?
Uncharacterized protein FAM215A, Apoptosis-related protein 2, APR-2.
Protein: VP2_SOUV3
Sequence: MAQAIIGAIAASAAGSALGAGIQAGAEAALQSQRYQQDLALQRNTFEHDKDMLSYQVQASNALLAKNLNTRYSMLIAGGLSSADASRAVAGAPVTRLIDWNGTRVAAPRSSATTLRSGGFMAVPMPVQPKSKTPQSSGFSNPAYDMSTVSSRTSSWVQSQNSLRSVSPFHRQALQTVWVTPPGSTSSSSVSSTPYGVFNTDRMPLFANLRR
What is the function of this protein?
Minor structural protein present in one or two copies per virion.  Stabilizes capsid protein VP1 by protecting it from disassembly and degradation.  May play a role in RNA genome packaging (By similarity).
What are the official names of this protein?
Protein VP2, Minor capsid protein.
What is the protein family that this protein belongs to?
Belongs to the norovirus VP2 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: ZN668_BOVIN
Sequence: MEVESPEERSPAPGYKRSGRRYKCLSCTKTFPNAPRAARHAATHGLADCTEEMAEAKLKPETDPKAEDASGDKVSGAAAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRGHTGERPYTCADCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEGVKPYRCEKCGKDFRQPADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTHRSSEATGAPPQQELVVGLALPVSMAGEGPAAPASGAALGDPPAGLLGLPSESGGVMATQWQVVGMTVEHVECQDAGVGEAPGPLGAAGEVGGEEVDEKPPQFVCRECKETFSTLTLLRRHERSHPELRPFHCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTHPVPIGTPTPLEPLVALLGMPEEGPA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 668.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HPR1_ARATH
Sequence: MAKPVSIEVYNPNGKYRVVSTKPMPGTRWINLLVDQGCRVEICHLKKTILSVEDIIDLIGDKCDGVIGQLTEDWGETLFSALSKAGGKAFSNMAVGYNNVDVEAANKYGIAVGNTPGVLTETTAELAASLSLAAARRIVEADEFMRGGLYEGWLPHLFVGNLLKGQTVGVIGAGRIGSAYARMMVEGFKMNLIYFDLYQSTRLEKFVTAYGQFLKANGEQPVTWKRASSMEEVLREADLISLHPVLDKTTYHLVNKERLAMMKKEAILVNCSRGPVIDEAALVEHLKENPMFRVGLDVFEEEPFMKPGLADTKNAIVVPHIASASKWTREGMATLAALNVLGRVKGYPIWHDPNRVDPFLNENASPPNASPSIVNSKALGLPVSKL
What is the function of this protein?
Catalyzes the NADH-dependent reduction of hydroxypyruvate into glycerate in the photorespiratory core cycle.  Mediates fatty acid beta-oxidation in germinating seeds when malate dehydrogenase is absent.
What are the official names of this protein?
Glycerate dehydrogenase HPR, peroxisomal, GDH, NADH-dependent hydroxypyruvate reductase 1, AtHPR1, HPR 1.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: ES30_TRICO
Sequence: GNTYSANNKQQTDIEQLMPKYNSTFAKMNGNYSYKLIWDDSMVSDALQEAKEQYSTNATFKIRRRKVFIKGDNATMEEKVEGALKYPVLRADKFLRRLLWFTHYACNGYYDTKGGHDVLTVACLYREIDYKNSHY
What are the official names of this protein?
30 kDa antigenic glycoprotein, ESGP30.
What is the protein family that this protein belongs to?
To H.contortus 15 kDa excretory/secretory protein.
What are the subcellular locations of this protein?
Secreted.
Protein: FOSA_PSEAE
Sequence: MLTGLNHLTLAVADLPASIAFYRDLLGFRLEARWDQGAYLELGSLWLCLSREPQYGGPAADYTHYAFGIAAADFARFAAQLRAHGVREWKQNRSEGDSFYFLDPDGHRLEAHVGDLRSRLAACRQAPYAGMRFAD
What is the function of this protein?
Metalloglutathione transferase which confers resistance to fosfomycin by catalyzing the addition of glutathione to fosfomycin.
What are the official names of this protein?
Glutathione transferase FosA, Fosfomycin resistance protein.
What is the protein family that this protein belongs to?
Belongs to the fosfomycin resistance protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAX3A_BUTOS
Sequence: MKVFFAVLIALFVCSMVIGIHGGVPINVKCRGSRDCLDPCKKAGMRFGKCINSKCHCTP
What is the function of this protein?
Inhibits insect potassium channel.  Is at least a 100-fold more potent against the Drosophila Shaker channel than towards its mammalian homologs Kv1. 1/KCNA1 and Kv1. 3/KCNA3.
What are the official names of this protein?
Potassium channel toxin alpha-KTx 3.10, BoiTx1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 03 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PAND_WOLSU
Sequence: MKFDMLWSKIHRATVTDANLNYVGSITIDEELMEAAELLVGQKVEILDVNNGERFSTYVIRGERGSREICLNGAAARKVAIGDKIIIVAYAQYDRSELSSYKPTVVLVDEKNDIVQIKHEV
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_BORBR
Sequence: MSTSAADTLSRPSGRAVDALRPFSLERGFTRYAEGSVLVRAGNTHVLCTASVLEKVPPFLKGRGEGWVTAEYGMLPRATHTRGDREAARGKQSGRTQEIQRLIGRSLRAVFDLRLLGERTLHLDCDVLQADGGTRCASITGAWVAAADAVALLMQRGDLAHNPIRDAVAAVSVGLVDGRAVLDLDYQEDSACAADVNVVMTGSGAFVEVQGTGEGATFTRGELDTMLGLAEGGIAQLVRAQREALQ
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PURA_MYCGI
Sequence: MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGILTPGVTNVIGNGVVVDPGVLLTELKGLEDRGVDTDRLLISADAHLLMPYHVAIDKVVERYAGSKKIGTTGRGIGPCYQDKIARQGIRVADVLDPAVLAEKIEGALELKNQVLVKIYNRKALEPAEVVENLLEQAEGFKHRIADARLLLNEALERDEIVLLEGSQGTLLDVDHGTYPYVTSSNPTAGGASVGSGIGPTRITTVLGILKAYTTRVGSGPFPTELFDEHGAYLAKTGGEVGVTTGRARRCGWFDAVIARYATRVNGITDYFLTKLDVLSSLETVPICVGYTVDGKRTDEMPMTQSDIARAEPVYEELPGWWEDISGAREFDDLPAKARDYVLRLEELAGAHVSCIGVGPGRDQTIVRRDILATS
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAS1_CHAGB
Sequence: MASDLSKKRKFKDSKGSKPERALASSSKAKKLKRAPTPEDSDAERDNSSDPEIENQEPEVEVPGPPQDNSEDQEAEENANAFERQDEPAGLDSAIQKGDGSLLGPSVSTDAQAFSELNLSDKTMMSINEMGFTKMTEIQRRGIPPLLAGKDVLGAAKTGSGKTLAFLIPAIEMLNSLRFKPRNGTGVIVVTPTRELALQIFGVARELMKNHSQTYGVVIGGANIRAEEDKLGKGVNLLIATPGRLLDHLRRGSFVFKNLKSLIIDEADRILEVGFEDEMRHIVKILPKENRQTMLFSATQTTKVEDLARISLRPGPLYINVDEEKQFSTVEGLDQGYVIVDADKRFLLLFSFLKKMAKKKIIVFLSSCNSVKYYSELLQYIDLQVLDLHGKQKQQKRTNTFFEFCNAKQGTLICTDVAARGLDIPQVDWIVQFDPPDDPRDYIHRVGRTARGNNTKGRSLLFLQPCELGFLAHLKAAKVPVVEYDFPKNKILNVQSQLEKLIGSNYYLNQSAKDGYRSYLHAYASHSLRSVFDVQKLDMVKVAKGFGFSTPPRVDITLGAGMSRDKKPQARRAYGSQPRQSGHQRR
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GRPE_RHOPA
Sequence: MTETDGQKDNNQDTAQAAADPVVSKPYIMPDDPEEGSNEALVREAADARDKMLRTLAEMENLRKRTQKEVADARTYGVTSFARDVLDIADNLQRALDAVPADARANAEPGLKALIEGVELTERSLLNALEKNGVKKFDPKGQKFDPNFQQAMYEVPDPSVPAGTVVQVVQAGFTIGDRVLRPALVGVAKGGAKAAPSDGGGETGNLN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYL8_ARATH
Sequence: MEANGIENLTNPNQEREFIRRHHKHELVDNQCSSTLVKHINAPVHIVWSLVRRFDQPQKYKPFISRCVVKGNMEIGTVREVDVKSGLPATRSTERLELLDDNEHILSIRIVGGDHRLKNYSSIISLHPETIEGRIGTLVIESFVVDVPEGNTKDETCYFVEALIKCNLKSLADISERLAVQDTTESRV
What is the function of this protein?
Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition.  Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) in an ABA-independent manner but more efficiently when activated by ABA.  Confers enhanced sensitivity to ABA (PubMed:19407143, PubMed:19624469, PubMed:19769575, PubMed:19889877, PubMed:23844015, PubMed:21658606).  Can be activated by both (-)-ABA and (+)-ABA (PubMed:23844015).  Mediates crosstalk between ABA and auxin signaling to regulate lateral root growth.  Required for lateral root growth suppression by ABA.  In response to auxin, promotes lateral root growth by enhancing MYB77-dependent transcription of the auxin-responsive gene IAA19.  Enhances the abilities of MYB44 and MYB73 to activate IAA19 gene (PubMed:24894996).
What are the official names of this protein?
Abscisic acid receptor PYL8, ABI1-binding protein 1, PYR1-like protein 8, Regulatory components of ABA receptor 3.
What is the protein family that this protein belongs to?
Belongs to the PYR/PYL/RCAR abscisic acid intracellular receptor family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Nucleus. Cell membrane. Note=Localizes at the plasma membrane in the presence of a CAR protein (e.g. CAR1 and CAR4).
Protein: ORCO_HARSA
Sequence: MMKMKQQGLVADLLPNIRVMKFFGHFVFNYYDDNSSKYLHKIFCCVNLFLLLLQFALCAVNLIIESADVDDLTANTITLLFFTHSIVKIIYFAVRSKYFYRTWAIWNNPNSHPLFAESNARYHAIALKKMRLLLFLVGATTVLSAIAWTVLTFFEHPIRKLVDPVTNETTIIELPQLLLRSYYPFDASKGIMHVIVLIYQFYWVLFMLIDANSLDVLFCSWLLFACEQLQHLKQIMKPLMELSATLDTVVPNSSELFKAGSAEHLRESENQPPPPVPPQGDSMLDLDLRNIYSNRQDFTATFRPTAGMTFNGGVGPNGLTKKQEMLVRSAIKYWVERHKHIVRLVTAVGDAYGFALLLHMLTTTITLTLLAYQATKVNGVNVYAASTIGYIIYTFGQVFLFCIFGNRLIEESTSVMEAAYSCHWYDGSEEAKTFVQIVCQQCQKAMSISGAKFFTVSLDLFASVLGAVVTYFMVLVQLK
What is the function of this protein?
Odorant coreceptor which complexes with conventional odorant receptors (ORs) to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability (By similarity).  Obligate coreceptor of all odorant receptors (By similarity).  Orco is a universal and integral part of the functional odorant receptor, involved in the dendritic localization of other olfactory receptors.  Can form functional ion channels in the absence of an odor-binding odorant receptor (By similarity).  Plays a central role in the perception of olfactory stimuli in ants and is essential for ant social organization (PubMed:28802043).  Required for pheromone sensing and mating behavior (PubMed:28802043).  Also required for the development and maintenance of odorant receptor neurons (ORNs) and of antennal lobe glomeruli (PubMed:28802043).
What are the official names of this protein?
Odorant receptor coreceptor.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Orco subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCH1_XYLFM
Sequence: MDHSKQQNASITQAQAEEAVRTLLRWAGEDPTREGLLDTPRRVVEAYGDWFSGYREDPHDYLQRTFEEISGYDEMIVLRNITYESHCEHHMAPIIGKVHVGYLPNGKVVGISKLARVVESYARRFQIQEKMTAQIAACIQETLSPRGVGVVIEGAHACMTTRGIHKRGVSMVTSKMLGTFREDARTRAEFLQFIEVGTNVMDL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GP4_EAVBU
Sequence: MKIYGCISGLLLFVGLPCCWCTFYPCHAAEARNFTYISHGLGHVHGHEGCRNFINVTHSAFLYLNPTTPTAPAITHCLLLVLAAKMEHPNATIWLQLQPFGYHVAGDVIVNLEEDKRHPYFKLLRAPALPLGFVAIVYVLLRLVRWAQRCYL
What is the function of this protein?
Minor envelope protein.  Part of the glycoproteins heterotrimer GP2b-GP3-GP4 which is probably responsible for the attachment to target host cell.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis.
What are the official names of this protein?
Glycoprotein 4, Protein GP4.
What is the protein family that this protein belongs to?
Belongs to the arteriviridae GP4 protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single- pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Secreted. Note=Only a small fraction of GP4 synthesized in infected cells ends up in virions.
Protein: REPA_NEIGO
Sequence: MPNDLVVVKANSLIEANYRLSIDEIRILALTIGTMDPKSNQKIFDFTVADFVREFPEISQDNAYKQIQAAIKRIYDRSVKTEDKDRVTEFRWVSSRTYFKKEGRFRIAMTDEVMPYLTQLKGQFTQYQLKHIAYFNSVHSIRIYELITQYRSVGSREITVEKLKEWLQVENKYPRFNSLNQRVLEPAITEINEKSDLVVEVEQIKRGRTIHSLNFVIGSKKRTAQKIEEVAKRPVFPHKNKYGKFVKLDKQNPKMSNHEYGLWARDCLKILEDHYTDITKVTNEDLRNYWVFLAGNDSNRSKLGSKSDFLNELKKRGYKLVDCELVKI
What are the official names of this protein?
Replication protein.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: GLYCO_RABVT
Sequence: MVPQALLFVPLLVFPLCFGKFPIYTIPDKLGPWSPIDIHHLRCPNNLVVEDEGCTNLSGFSYMELKVGYISAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKMAGDPRYEESLHNPYPDYHWLRTVKTTKESLVIISPSVADLDPYDKSLHSRVFPSGNCSGITVSSTYCSTNHDYTIWMPENPRLETSCDIFTNSRGKRASKGSKTCGFVDERGLYKSLKGACKLKLCGVLGLRLMDGTWVAMQTSDETKWCPPDQLVNLHDFRSDEIEHLVVEELVKKREECLDALESIMTTKSVSLRRLSHLRKLVPGFGKAYTIFNKTLMEAEAHYKSVQTWNEIIPSKGCLRVGGRCHPHVNGVFFNGIILGPDGHVLIPEMQSSLLQQHMELLESSVIPLMHPLADPSTVFKDGDEAEDFVEVHLPDVHKQVSGVDLGLPNWGKYVLLSAGTLIALMLIIFLMTCCRRVNRPKSTERSLGETGRKVSVTSQSGKVISSWESYKSGGETRR
What is the function of this protein?
Attaches the virus to host cellular receptor, inducing endocytosis of the virion.  In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane.  There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the lyssavirus glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: RF1_HELPH
Sequence: MSILAEKLSSILKRYDELTALLSSAEVISDIKKLTELSKEQSSIEEISIASKEYLSVLENIKENKELLEDKELSELAKEELKILEIQKSDLETAIKQLLIPKDPNDDKNIYLELRAGTGGNEAGIFVGDLFKAYCRYADLKKWRVEIVSSSENSVGGYKEIIALIKGKGVYSRLKFEAGTHRVQRVPETESQGRIHTSAITVAIMPEVDDVEVSINPSDLKIEVFRAGGHGGQCVNTTDSAVRITHLPTNISVSMQDEKSQHKNKDKALKILKARLYEKQIEEQQLANAKDRKEQVGSGDRSERIRTYNYPQNRLSEHRINLTLYSLEEIMLSGNLDEVINPLIAHAQSQFE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA12_RAT
Sequence: MTALLFLGSLLMSLDLTLSAPPWKSKEFKDGAGDPSVVLTVDGKLCHFPFQYHRRLYHKCIHKGQPGSRPWCATTPNFDEDQQWGYCLEPKKVKDHCSKHSPCHKGGTCVNTPNGPHCLCPEHLTGKHCQREKCFESQLLKFFHENEIWFRTGPGGVARCQCKGPQAVCKLLTSQVCRVNPCLNGGTCLLVEDHRLCHCPAGYAGPFCDLDLKATCYEDRGLSYRGQAKTTLSGAPCQRWASEATYRNMTETQALSWGLGHHAFCRNPDNDTRPWCYVWSGDRLSWDYCDLEQCQMPTLTSPVSPESHDMLKPRPPILQSSPRDSTRNQNVVSRTSTVVCGQRFRKRLSSLRRVVGGLVALPGSHPYIAALYWGDSFCAGSLIDPCWVLTAAHCLQKRPAPEELTVVLGQDRHNQSCERCQTLAVHSYRLHEGFSSKTYQHDLALLRLRGRKNSCAILSPHVQPVCLPSSAAPPSETVLCEVAGWGHQFEGAEEYATFLQEAQVPFISLDRCSSSNVHGDAILPGMLCAGFLEGGADACQGDSGGPLVCDEGVTERQLTLRGVISWGSGCGDRNKPGVYTDVANYLDWIQEHTAF
What is the function of this protein?
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin.  Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa.  Alpha-factor XIIa activates factor XI to factor XIa (By similarity).
What are the official names of this protein?
Coagulation factor XII, Hageman factor, HAF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSACC_HUMAN
Sequence: MERHTSHPNRKVPAKEEANAVPLCRAKPSPSYINLQASSPPATFLNIQTTKLPSVDHKPKECLGLLECMYANLQLQTQLAQQQMAVLEHLQASVTQLAPGRGSNNSSLPALSPNPLLNHLPQFSK
What is the function of this protein?
Co-chaperone that facilitates HSP-mediated activation of TSSK6.
What are the official names of this protein?
TSSK6-activating co-chaperone protein, SSTK-interacting protein, SIP, SSTK-IP.
What is the protein family that this protein belongs to?
Belongs to the TSACC family.
Protein: NQOR_BRUA2
Sequence: MVKMLVLYYSAYGYMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEVPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGMTTTADGDGSRQPSAQELDGARFQGRRVAEITAKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: YV006_HUMAN
Sequence: MTMTMSYKAIEKIPRCSWNREEPGEQWNKIYSVETGLLGTYSFEWQSQVANKTMRKRNTNSICGRQHEPHCPVSITRAIAQPQLLTFPDSLASRGGHMTQSGQCHVSGSLLGRGHKSRGR
What are the official names of this protein?
Putative uncharacterized protein FLJ36925.
Protein: RBGA_BACCR
Sequence: MVIQWFPGHMAKARRQVTEKLKLIDVVIELVDARLPLSSRNPMIDEIITHKPRLVVLNKADMADDRLTKQWIAYFKEKGHMAISINAQAGQGMKEIAAACKVLVKEKFDKMVAKGIRPRAIRALIVGIPNVGKSTLINKLAKKNIAKTGDRPGVTTAQQWIKVGKEMELLDTPGILWPKFEDQLVGLRLATTGAIKDSILNLQDVAVYALRFMEKHYPERLKERYNLNEIPEDIVELFDAIGKNRGCLMGGGMIDYDKTSELVLRELRGGKLGKMTFETPEEFGEQVEDVEKIEEV
What is the function of this protein?
Essential protein that is required for a late step of 50S ribosomal subunit assembly.  Has GTPase activity that is stimulated by interaction with the immature 50S ribosome subunit.  Binds to the 23S rRNA.  Required for the association of ribosomal proteins rplP and rpmA with the large subunit (By similarity).
What are the official names of this protein?
Ribosome biogenesis GTPase A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.