PharMolix/UniProtQA huggingface dataset:
Protein: FLIT_BACSU
Sequence: MNNIDQLYTETKSMLSHIQNTPESDELLKQIEDFVATRSELIQEISLPLSEEERKQMKLILTWDQLIVKEMERLKQSIATELQQMKRKRVMHTTYLNPYNNITIDGTYYDKRK
What is the function of this protein?
May act as an export chaperone for the filament capping protein FliD.
What are the official names of this protein?
Flagellar protein FliT.
What is the protein family that this protein belongs to?
Belongs to the bacillales FliT family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: VMA21_ASPFC
Sequence: MTSRRSQEKSYAEAAAAPPPKESASSDVTPAVPADVIYKLLGFTAAMVVGPIGMYFVTVNSGGMSFFHQTSNFSLFETLTRIASPTVAGITAAITANLVLFGYIYVAWLDDREEREAASKRNEKKAQ
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein vma21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: MURQ_JANSC
Sequence: MGVAAVFTAVQSDLGALVSEASNSRSADIDLMTTAQILACMNAEDRKIADAVAAELPAIAQTVDRIVAAIGRGGRLIYIGAGTSGRLGVLDASECPPTFSVPPGMVVGLIAGGDTALRTSVEAAEDDEATGAEDVKAIGLTTKDVVIGIAVSGRTPFVMGAIDYARRIGAFTAALTCNPGSPMADLADIAISPVVGPEVVTGSTRLKSGTAQKMILNMLSTASMIRLGKTWGNRMVDVTISNRKLADRATAMLRDATGCSADDARTLLDQSNGSVKLAILMQITGCDADAARANLEAENGFLRKAIERAEKTPPQS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: SYFA_YERPG
Sequence: MPHLAELVAKAKAAVEGAQDIAALDLVRVEYLGKKGHLTLQMTSLRELPAEERPAAGAVINQAKQEVQEALNARKEKLESAVLNARLAAETIDVSLPGRRMENGGLHPVTRTIERIETFFGELGFSVESGPEIEDDYHNFDALNIPAHHPARADHDTFWFDATRLLRTQTSGVQIRTMQEQQPPIRIIVPGRVYRNDYDQTHTPMFHQMEGLIVDRDISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_CAMC5
Sequence: MDVVAFFTEILKFRSITPDDDGCLKFIAEFLGDFEARFIEKNGVKNLILSKRFGDGAHLAFAGHVDVVPPGEGWQSEPFTPLMKDGFIYARGAQDMKSGVAAFVCACRDAKNFNGRLTLILTSDEEGDALFGTLEALKILKERGELPQFAVVAEPTCTGVFGDTIKVGRRGSINGKILIRGVQGHVAYPEKCVNPVHQIAPLLSRIAGHDMDAGSEFFSPSKIVITDIRGGMEVCNVTPSELGIMFNVRNSDITSADDVKNYLQSVLEGLNFELSLKQSSKPFLTDKDSKIVRAMSKAVQKISGVAPQLNTKGGTSDARYLAEFGVKVVEFGVINDRIHAVDERAGVKEVERLYLVFKELIENFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ORN_YEAST
Sequence: MKWLLFPARIVARTRPNLFSLYRRSVSQYLRPRTIQNLQSMAQTPELKTKLFKPLVWIDCEMTGLDHVNDRIIEICCIITDGHLAPVKAADGQGDSHYESVIHYGPEVMNKMNEWCIEHHGNSGLTAKVLASEKTLAQVEDELLEYIQRYIPDKNVGVLAGNSVHMDRLFMVREFPKVIDHLFYRIVDVSSIMEVARRHNPALQARNPKKEAAHTAYSDIKESIAQLQWYMDNYLKPPQETESVESIGSEQPESPSSSTSSLKRQRTDF
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: EX7S_CITK8
Sequence: MPKKNEAPASFETALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASPEPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBPA_PECAS
Sequence: MRNPDFSPLYRSAIGFDRLFNLLETGQTQSNGGYPPYNVELVDENQYRIAIAVAGFAEQELDITAHDNLLIVKGAHAGEQVARNYLYQGIAERNFERKFQLAEHIQVKGANLENGLLYIDLERIVPEAMKPRRIEIK
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AES_SHIBS
Sequence: MKPENKLPVLDLISAEMKTVVNTLQPDLPSWPATGTIAEQRQYYTLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDTHDRIMRLLASYSQCTVIGIDYPLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKIVGVLLWYGLYGLRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLAAHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL
What is the function of this protein?
Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons).  Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate.  Negatively regulates MalT activity by antagonizing maltotriose binding.  Inhibits MelA galactosidase activity.
What are the official names of this protein?
Acetyl esterase.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA_LEPMC
Sequence: MSHMDAEDAQFQKEVAEVKQWWNDSRWRYTKRTFTAEEIVSKRGNLKITYPSNSQSKKLWNIVEHRFKNKDVSYTYGCLDPVMVTQMAKYLDTVYVSGWQASSTASSTDEPGPDLADYPYTTVPNKVGHLFMAQLFHDRKQREERLTTPKADRAKVANVDYLRPIIADADTGHGGLTAIMKLTKLFIEKGAAGIHIEDQAPGTKKCGHMAGKVLVPISEHINRLVAIRAQADIMGTDLLAVARTDSEAATLITSTIDPRDHYYIQGCTNPALQPLSELMYAAEQSGKSGSELQAIEDAWVKEANLKLFHEAVVDTINAGVHVNKQELINQFLEQSKGKSNAEARTIAQGLTGVDVYFNWDAARTREGYYRYKGGCQCAINRAIAYAPFCDMIWMESKLPDYAQAKEFADGVHAVWPEQKLAYNLSPSFNWKAAMPRDEQETYIQRLAQLGYCWQFITLAGLHQSALMADTFSKAYSKQGMRAYGEIIQEPEAENKVDVLTHQKWSGANYVDNMLKMVSGGVSSTAAMGKGVTEDQFK
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate (By similarity).  Plays an important role in plant pathogenicity.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: SPRT_PSEP1
Sequence: MPEQLKQRVETCYQQAEAFFKRRFPRPEVSFKLRGQKAGVAHLHENLLRFNLQLYRENQEDFLRQTVAHEVAHLVAHQLFGDRIQAHGEEWQLIMRGVYELPPNRCHNYDVQRRAVTRYIYRCPCPQSDFPFTAQRHKLVHQGRRYLCKRCREILVYSGETRVE
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAE2_SYMTH
Sequence: MSFVHLHVHSPFSFLDGASRLDDLIAEAALHGMPALALTDHNNVSGAVRFQRKAQEAGIQPIQGAELTLEGGYHLTLLATGPKGYANLNRLITAAHLGQEPRATPGAMFALAPGHDRLQPACPLSALSHDTDGLIALSGCRRGEIPSLILRGRLAEAEAAARRYAAWFPGRFYLELHDERLPGEQALNRALRDLGEALGLPLVVTSNVHHRTREEFFVHDLLTCVRTLTRIDQPHPERPLNDQRYLKPPEVMIERFREFPEAVKNTLAIAERCRPVLDLDARLHPEFQTPDGSHPAAYLTHLVYDGAARRYGRITERIRRRLEHELTIITRLGYEDYFLLVWDVVRFARERGIRCAGRGSAADSAVAYCLFITDVDAIERGLLFERFMSLERAQKPDIDIDFDARRRDEVAAYVYRKYGADHVASVCTYNTFQARSAVRDLGKAMGFQEADLDYLAKRIPWHAGADEILTVMARYPELRQSGIPWHKFEQLVQAAERVARFPRFIGTHLGGLVISRRPLLEVTPLQMAAKGQVVCQFDKEYVEDLGLVKLDLLSLRTFTAVDDAVRAIGDIDYEQIPHGDAATYEMLGVGESIGVFQLESPAQRALQARLKPDRFEDIVASVAIIRPGPIKGNMVEPFLARRHGKEEVTYLHPKLKPILEKTYGVVLFQEQVIEIATAVAGFTPGEADQLRRVMTHARNREDMEAIGRLFRQKAAAAGVDPAVADTIFSYIQGYASYGFCEAHAAAFANTAYKTAYLVRHYPAEYFAALMSAQPMGYYPINTLAVEARRRGVGLLPVDINRSEEAFTVEEWSREAWEAFWGMEPFAPEYPATGKAIRIGLRAVKGVGEPAAAAILAARDGGEFRSLADLVRRTGGAVPRGPLEALVLAGAFDRLHSNRRAALWQVAHLLEAERIRQERGAGQAGLLDGDAPGLGAQAAEALEAASPQGTPAIADFGAAERYLKEYELTGLMVRTHFMRFVRERLAREGYLTAQEVRQRRAGELVKVAGLPVCPHRPPTRSGKIVVFLSLEDETGLIDLTIFEDVYQRYGHLIFTDPRPPLAALGRVDRRGGHVSITVNRLRLLDT
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_VIBPA
Sequence: MLKIGDKEFKSRLFTGTGKFSNSHLMAEAIQVSGSQLATMALKRVDVHDQQDDILQPLIHAGVNLLPNTSGAKNAKDAVFAAQLAREALGTNWVKLEIHPDPKYLMPDPIETLAAAEQLVRDGFIVLPYCHADPVLCKRLEEVGCAAVMPLGAPIGSNKGIASHDFLEIIIDQANVPVVVDAGIGAPSHAARAMEMGADAVLVNTAIAAASNPVAMAKAFKMAVESGRMAYKAGLAGKVSHAVASSPLTAFLDEL
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_LEIXX
Sequence: MTRHFLRDDDLSPAEQVEVLDLAAKLKRDRFSARPLAGPQTVAVMFDKTSTRTRLSFATGIADLGGNPLIIQAGESQVGAKESLADTARVMERMLAAIVWRTFAHSGLEELVDGTRIPVVNALSDDVHPCQTLADLQTVRERKGRTAGLTMSFFGDGASNMAHSSLLGGVTAGMRVRIAAPAGYTPDPRFVADAEAIAARTGGSVLVTADPGEAAAGADVIVTDTWVSMGKEDEKAERIAVFGDYAVNAGTLRLADPAAIFLHCLPAYRGLEVSAYVIDGPQSVVWDEAENRLHAQKALLTWLLAKNREDAV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_HELPJ
Sequence: MAKRNVTAKKKVVKKNIARGVVYISATFNNTNITITDEMGNVICWSTAGGLGFKGSKKSTPYAAQQAVESALSKAKEHGVKEVGIKVQGPGSGRETAIKSVGATEGVKVLWIKDITPLPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: HSLU_SALPC
Sequence: MSEMTPREIVSELNKHIIGQDNAKRSVAIALRNRWRRMQLDEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQAEQQQEPSAARQTFRKKLREGQLDDKEIEINLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKPRKLKIKDAMKLLVEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGETSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELQALTTSDFERILTEPNASVTVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNETTENIGARRLHTVLERLMEEISYNASDLHGQNITIDAEYVSKHLDALVADEDLSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Heat shock protein HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y502_RICPR
Sequence: MLKRTYIRTLTEDLALSLQSLGFVLELRRTQVGIFKAENAIKIKSSDEITKNFIEKKSIKIEAILDDILVLDATDDQAQRIKYGQKCVFDYEEDVSFLWVRYNGTLLAIGSLNKSCFNSLRVFNLL
What are the official names of this protein?
Uncharacterized protein RP502.
Protein: SYA_SULIA
Sequence: MKASEEEYRLNFFIKNDFKRKICKSCKTPFWTRDEKKEYCSDIPCTDYYFFDINIKSQPLTVKEAREKFLSFFEKRGHTRISPKPVLARWREDLYLTIASIVDFQPHVTSGLVPPPANPLVVSQPSIRLEDIDNVGITFGRHLTTFEMAAHHAFNYPDHYVYWKEETTAYATEFFTKELGIPEEELNFKESWWEGGGNAGPCLEVTVGGLELATLVFMQYKITDNGNYTPLKLKIVDTGYGVERIAWITQKTPSAFHAIYGNLVYKFFNKIGVAYIDETLLKVASRFAGKIDPDNPDTIKIHRQMVSKELGIDIKAVEEELDRAAKVFQILDHTKTIMLMLADGLVPSNSGEGYLGRLVIRRALKVLRLLKSDVRLYELVKEQIDFWKEDFPQVLKNKDYILDAVELEQQRFEKILEKVPSIASTLARKSEITTEDLIQVYDSNGIPPDLLEEELKKKSVKFELPRNFYALVAKRHQTSTIKSAYDKVKLPKDMLEYITALQPTEKLYYKDQYMRSFEGKVLGVYKNYLILDKTTFYPEGGGQLGDTGLIIDEKSSKRYEVIDTQKVNDVIVHILKEEPSTIKVGDNVRGEINWERRYRLMRHHTVTHVILAAAKKVLGEHVWQAGAEKTPEKGRLDITHHKTLTEEEVKLIENYANSVISDRRPVKPLEMNRMEAEMKYGVSIYEGGVPNSATIRLLEIKDWDIESCGGTHVSNTSEIGAVKIINVERIQDGVIRLEYVAGPALVDYIRETEAKIVEASKIIGSSPDQLTSRLRRILNEIEEKNNLIIQYRRIIETELLNNLKPYEINGNKIYIIEGLGDEEENKEILRKLTSTDNTIAISISDNRLQIATSKNMRVDKIVEELLKGGGKGGGKGTFANVILNSKKSKEEIIEIVRKSL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_LAWIP
Sequence: MAKPKRIGKKREKKNIPVGVVHIQASFNNTIITFTDPRGNTISWASSGQSGFKGSRKSTPFAAQVAAEQAARRAQDNGMRTVGIYVKGPGSGRESAMRAINAVGFKVAFIRDITPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TESS_TERAN
Sequence: MKCSVLQMSRLSWTACVLLLPLLLLTLQGGVQGCFIRNCPRGGKRAVDSVQPTRQCMSCGPEGVGQCVGPSICCGLAIGCLMGTPEAEVCQKENESSAPCAVSGRHCGMDNTGNCVADGICCVEDACSFNSLCR
What are the official names of this protein?
Terepressin/terephysin, Conopressin/Conophysin-like.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPA_METS4
Sequence: MTTRLDDTFARCRAEGRAALVTYVMAGDPDPETSLQVLRALPEAGADIVEFGLPFTDPMADGPAIQAAGLRALKAGQTVSGTLALVRRFRAENRTTPVILMGYYNPLYIYGVARFLADAVAAGVDGLIVVDLPPEEDDELCLPTQEAGLAFIRLATPTTDERRLPAVLANTSGFVYYVSITGITGSATPDFGQVEAAVARIRARTALPVVVGFGVKTGAHAAAIARGADGVVVGSALVDALARSLDLDGRATSGSVAAVSALVRDLAAGVRAAAR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: KAIA_NOSS1
Sequence: MTQEVDQQILLQQLKSDYRQILLSYFTTDKALKEKIDKFINAVFCANIPVPEIIEIHMELIDEFSKQLRLEGRGDETLMDYRLTLIDILAHLCEAYRGAIFK
What is the function of this protein?
Key component of the KaiABC oscillator complex, which constitutes the main circadian regulator in cyanobacteria.  Complex composition changes during the circadian cycle to control KaiC phosphorylation.  KaiA stimulates KaiC autophosphorylation, while KaiB sequesters KaiA, leading to KaiC autodephosphorylation.  KaiA binding to the KaiC CII domain during the subjective day yields KaiA(2-4):KaiC(6) complexes which stimulate KaiC autophosphorylation.  Phospho-Ser-431 KaiC accumulation triggers binding of KaiB during the subjective night to form the KaiB(6):KaiC(6) complex, leading to changes in the output regulators CikA and SasA.  KaiB(6):KaiC(6) formation exposes a site for KaiA binding on KaiB that sequesters KaiA from KaiC's CII domain, making the KaiC(6):KaiB(6):KaiA(12) complex resulting in KaiC autodephosphorylation.  Complete dephosphorylation of KaiC leads to dissociation of KaiA(2):KaiB(1), completing 1 cycle of the Kai oscillator.
What are the official names of this protein?
Circadian clock oscillator protein KaiA.
What is the protein family that this protein belongs to?
Belongs to the KaiA family.
Protein: FIBB_THEGE
Sequence: NQEGLFGGR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPA_RHOP5
Sequence: MDIRAAEISAILKDQIKNFGQEAEVTEVGQVLSVGDGIARVYGLDNVQAGEMVEFENGTRGMALNLETDNVGIVIFGADREIKEGQTVKRTRSIVDTPVGKGLLGRVVDALGNPIDGKGPIVATERKRVDVKAPGIIPRKSVHEPMATGLKSIDALIPIGRGQRELIIGDRQTGKTAIALDTILNQKPLNVEGAPEGQKLYCVYVAIGQKRSTVAQFVKVLEEQGALEYSIVVAATASDPAPMQYIAPFTGCTMGEYFRDNGMHAVIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDEGNGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFQGIRPAVNVGLSVSRVGSSAQTKAMKKVAGKIKGELAQYREMAAFAQFGSDLDASTQRLLNRGSRLTELLKQPQFSPLKMEEQVVVIYAGVNGYLDPLPVAKVRAFEDGLLSLLRGKNVEILNAIRDSRDLSDDTAGKLKAVVEAYAKTFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NEK11_MACFA
Sequence: MLKFQEAAKCVSGSTAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDYKIQEYKEAGKIFPDNQIIEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNTIMESMLNKNPSLRPSAIEILKIPYIDEQLQHLMCRHSEMTLEDKNLDCQKEAARLINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADERARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLIGMEEKEEQPEGRPSCSPQDEDEERWQDREEEFDEPTLENLSEPQPIPSMDLRKLESIVEDATSDLGYHEIPEDPLVAEEYYADAFDSYCEESDEEEEEIVLAGPEKEIKNEGSQPTYRTNQQDSDIEALARCLENVLGCTSLDTKTIPSMAADVSPGPTIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRERLEKVVPRASDCFEVDQLLYFEEQLLITMGK
What is the function of this protein?
Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage.  Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
What are the official names of this protein?
Serine/threonine-protein kinase Nek11, Never in mitosis A-related kinase 11, NimA-related protein kinase 11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S-arrested cells.
Protein: SUB7_TRITO
Sequence: MGFITKAIPLALAAASVINGAEILETRAGVQTLADKYIVVMNDGMSDKDFDSHRSWVNRTHRRRLIRRGAKAMGGMKYTYNFPTGLKGYSGHFDEQMIKEISKRADVKYIERDARVQINAIEQQDNVPSWGLARVGSREPGGTTYYYDSTAGEGTTAYIIDTGTDIQHEEFDGGRATWGENFVDDMDMDCNGHGTHVSGTVGGRTFGVAKKSNIVAVKVLDCNGSGSNSGVIMGMQWATEDAQSKGADKAVVNMSLGGAFSQTSNDAAKAIAEGGVFLAVAAGNDNVDAAEASPASEPSICTVAASTEQDGKADFSNFGQVVDVYAPGDGITSAKPGGGSQVLSGTSMASPHVAGLAAYLIGLGKGGGPQLCDTIKQMAIDVIQNPGSSTTSKLINNGSGM
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LACA_STRP4
Sequence: MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTLAVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMITMGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.