PharMolix/UniProtQA huggingface dataset:
Protein: STC_ONCKI
Sequence: MLAKFGLCAVFLVLGTAATFDTDPEEASPRRARFSSNSPSDVARCLNGALAVGCGTFACLENSTCDTDGMHDICQLFFHTAATFNTQGKTFVKESLRCIANGVTSKVFQTIRRCGVFQRMISEVQEECYSRLDICGVARSNPEAIGEVVQVPAHFPNRYYSTLLQSLLACDEETVAVVRAGLVARLGPDMETLFQLLQNKHCPQGSNQGPNSAPAGWRWPMGSPPSFKIQPSMRGRDPTHLFARKRSVEALERVME
What is the function of this protein?
Its primary function is the prevention of hypercalcemia.  Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment.  STC also stimulates phosphate reabsorption by renal proximal tubules.  The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.
What are the official names of this protein?
Stanniocalcin, STC, Corpuscles of Stannius protein, CS, Hypocalcin, Teleocalcin.
What is the protein family that this protein belongs to?
Belongs to the stanniocalcin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCA_ECOL6
Sequence: MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLSFRIADETLALMREMTHAGELEHLTPERVWKETENALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEILDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAVASWKEQRCPKPD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: AROE_LACLS
Sequence: MKIDGYTRMAAVVANPIKHSLSPFIHNLAFDLTDENGVYLAWEVESKKLAAIVENVRNLDMYGLNISMPYKGEIIKFMDELSPAAELIGAVNTVVNHSGKIIGHNTDGIGFFNSLKKYDFKIENKQMLVLGGGGAAIALIAQAALSGAKKIVVAARKSASYDPLNEKLAKLSAKTGVEIFLTDLSGADRLQKELNQTDLLVNATSVGMDGASFPLEKSLLLPDRLLVVDAIYKVRETPFLRWAKEQGAQTENGLGMLIGQAAESFYLWTGKEMPVDKITLEMEREV
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: PABP_MAGO7
Sequence: MAAPSNTAAVDQLTSDLANANMNGGEKTTVNTNVGASFTGEEIDTAGPTPSSAAPHPQASASLYVGELDPSVTEAMLFELFSQIGSVASIRVCRDAVTRRSLGYAYVNYNTTADGEKALEELNYTLIKGRPCRIMWSQRDPALRKTGQGNVFIKNLDVAIDNKALHDTFAAFGNILSCKVAQDENGNSKGYGFVHYETDEAASQAIKHVNGMLLNEKKVYVGHHIPKKDRQSKFDEMKANFTNIYVKNINPEVTDDEFRTLFEKYGDVTSSSLARDQETGKSRGFGFVNFTSHEDASKAVQELNEKEFHGQNLYVGRAQKKHEREEELRKSYEAARQEKASKYQGVNLYIKNLDDEVDDEKLRQLFSEFGPITSAKVMRDSITEPGEEGESKEGEESEKNKENKPEEKEGDDSKPEEKEGEDSKSKSKLGKSKGFGFVCFANPDDATKAVAEMNQRMVNNKPLYVALAQRKDVRKNQLEQSIQARNQLRMQQAAAAAGMPQQYMQAPVFYGPGSQPGFMPPAGGRGMPYPQGGMPMQPGRPGQFPAGFAAQQGGRGAMPQGIPPMYGLPGQFPPQGPFPQPNNPQFLAAMQQIQQSALAGGRGGPAGRGPMQGGVPVPGMPGGAGLPGFPPNARQQGPGAGRGAAAGRAPAGAPAGARGAGAPEGLQGQLAAVADNPGQQKQILGEAIFPKIQAIHPELAGKITGMLLEMDNTELVALVENDGALRSKVDEALAVYDDYVRQQGDGEGAQAPSKEEKTEEKA
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.  In the nucleus, involved in both mRNA cleavage and polyadenylation.  Is also required for efficient mRNA export to the cytoplasm.  Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation.  In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein, cytoplasmic and nuclear, PABP, Poly(A)-binding protein, Polyadenylate tail-binding protein.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GSA_CHLPN
Sequence: MLNCSNQKHTVTFEEACQVFPGGVNSPVRACRSVGVTPPIVSSAQGDIFLDTHGREFIDFCGGWGALIHGHSHPKIVKAIQKTALKGTSYGLTSEEEILFATMLLSSLKLKEHKIRFVSSGTEATMTAVRLARGITNRSIIIKFIGGYHGHADTLLGGISTTEETIDNLTSLIHTPSPHSLLISLPYNNSQILHHVMEALGPQVAGIIFEPICANMGIVLPKAEFLDDIIELCKRFGSLSIMDEVVTGFRVAFQGAKDIFNLSPDITIYGKILGGGLPAAALVGHRSILDHLMPEGTIFQAGTMSGNFLAMATGHAAIQLCQSEGFYDHLSQLEALFYSPIEEEIRSQGFPVSLVHQGTMFSLFFTESAPTNFDEAKNSDVEKFQTFYSEVFDNGVYLSPSPLEANFISSAHTEENLTYAQNIIIDSLIKIFDSSAQRFF
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_SHEON
Sequence: MKASELREKSVEELNAELLGLLREQFNLRMQHATGQLTQTHQLKLVRRNIARVKTIITSKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: FMT_STRPZ
Sequence: MIKLLFMGTPQFSATVLKGLLDNPAYEILGVVTQPDRAVGRKKDIKVTPVKQLALEHGISIYQPEKLSGSQELIEIMGLGADGIITAAFGQFLPTILLDSVSFAINVHASLLPKYRGGAPIHYAIMNGDKEAGVTIMEMIKEMDAGDMVAKASTPILETDNVGTLFEKLAIIGRDLLLDSLPAYLSGELKPIPQDHSQATFSPNISPEHEKLDWTMSNQEVFNHIRGMNPWPVAHTFLEGQRLKIYEAQLAEGEGLPGQVIVKTKKSLVIATGQGALSLIVVQPAGKPKMSIIDFLNGIGRKLEVGDIIGR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: LFTR_BURCH
Sequence: MVPWLGPDDPFPSIERALGPATGAPGLLAASADLLPSRLIDAYLRGIFPWYSDGQPVLWWSPDPRMILVPAEFKVSPSLRKTLKRVLRAPEWEVRVDHDFAGVMRACAQAPRRGQRGTWITAEIIDAYTSLYRSGNAHSIETWHDGRRVGGLYGVSFGRMFFGESMYADVTDASKIALAALIAHLREQRLEMIDCQQNTSHLASLGGREIARKAFVAHVRSAVAEPPIPWQFDKRVLAALTSPAETAAPTGTER
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YB4E_SCHPO
Sequence: MASCCPTSRGAAASNKSYTFKGKEIENFGGLTTYVVGSTSNTRVLIGFMDIFGLSDQIKEGADKLADDGFTVYLPDFLEGKPLPVTALPPKTPEDQKLCNDFFSTRISPNLHWPKLAKVVEAVRANHGPNVTIGTYGFCWGAKVLVTYPATIDFVGIASCHPSFPDSADAANVHCPVLFLCSKDEDAKIIKEWEEAFKTNPAYAKSSFETFSDMFHGWMAARADLSNPEQRKRFDEGYQKVSSFFQSLM
What are the official names of this protein?
Uncharacterized AIM2 family protein C30D10.14.
What is the protein family that this protein belongs to?
Belongs to the AIM2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: E310_ADE05
Sequence: MIPRVFILLTLVALFCACSTLAAVSHIEVDCIPAFTVYLLYGFVTLTLICSLITVVIAFIQCIDWVCVRFAYLRHHPQYRDRTIAELLRIL
What is the function of this protein?
Down-regulates the EGF receptor.
What are the official names of this protein?
Early E3B 10.4 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E3B family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: DXS_POLSJ
Sequence: MYPLLETINSPADLRRLPRAQLKALADELRAFVLDSVSKTGGHLSSNLGTVELTVALHYVFNTPEDRLVWDVGHQTYPHKILTGRRDRMGSLRQFGGLSGFPRRDESPYDTFGTAHSSTSISAALGMALAAHQQGEDRHAVAIIGDGAMSAGMAFEALNNAGVHDDCKLLVVLNDNDMSISPPVGALNRYLAQLMSGRFYASAKNVGKQVLRVAPPLLELAKRLEAHAKGMVVPATLFENFGFNYIGPIDGHDLESLIPTLENIKHLKGPQFLHVVTKKGQGYKLAEADPVAYHGPGKFDPAMGLQKSSAPAKRTFTQVFGQWLCDMAEQDKRLVGITPAMREGSGMVEFHKRFPGRYHDVGIAEQHAVTFAAGMACEGLKPVVAIYSTFLQRGYDQLIHDVALQNLPVVFALDRAGLVGADGATHAGAYDIPFLRCIPNMSVACPADENECRKLLSSAFEQNHPVAVRYPRGAGAGVEPEPGLQPLPFGKGEIRREGSGVAILAFGTLLYPALQAAEKLGVTVVNMRWAKPLDTELLLKVAASHEALVTLEEGAIMGGAGSAVGEALQAAGLGKPLLQLGLKDEFIEHGDPAKLLALQGLDAAGIEAAVMARFGSVLQPEKSGKPAKPALKSVA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: M3K7_RAT
Sequence: MSTASAASSSSSSSASEMIEAPSQVLNFEEIDYKEIEVEEVVGRGAFGVVCKAKWRAKDVAIKQIESESERKAFIVELRQLSRVNHPNIVKLYGACLNPVCLVMEYAEGGSLYNVLHGAEPLPYYTAAHAMSWCLQCSQGVAYLHSMQPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGSNYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHNGTRPPLIKNLPKPIESLMTRCWSKDPSQRPSMEEIVKIMTHLMRYFPGADEPLQYPCQYSDEGQSNSATSTGSFMDIASTNTSNKSDTNMEQVPATNDTIKRLESKLLKNQAKQQSDSGRLSLGASRGSSVESLPPTSEGKRMSADMSEIEARIVATTAYTKPKRGHRKTASFGNILDVPEIVISGNGQPRRRSIQDLTVTGTEPGQVSSRSSSPSVRMITTSGPTSEKPARSLPWTPDDSTDTNGSDNSIPMAYLTLDHQLQPLAPCPNSKESMAVFEQHCKMAQEYMKVQTEIALLLQRKQELVAELDQDEKDQQNTSRLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQGTS
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  Plays an important role in the cascades of cellular responses evoked by changes in the environment.  Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR).  Ceramides are also able to activate MAP3K7/TAK1.  Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7.  These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK).  Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK.  MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis.  In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B (By similarity).  Promotes TRIM5 capsid-specific restriction activity (By similarity).  Phosphorylates RIPK1 at 'Ser-321' which positively regulates RIPK1 interaction with RIPK3 to promote necroptosis but negatively regulates RIPK1 kinase activity and its interaction with FADD to mediate apoptosis (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase 7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Although the majority of MAP3K7/TAK1 is found in the cytosol, when complexed with TAB1/MAP3K7IP1 and TAB2/MAP3K7IP2, it is also localized at the cell membrane.
Protein: Y466_POLNA
Sequence: MTTPCPCGRTSANSAKPAKTQPLPFFACCGPYLNESVPAPDAHALMRSRYSAFVLQRADYLLATWHASTRPAALDFAPGAKWLGLDVRSHRVLDADHAEVEFVARCREAGRATRLHERSRFVRESERWFYVDGDQF
What are the official names of this protein?
UPF0225 protein Pnap_0466.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: NU1C_CYCTA
Sequence: MVINTTDPEERVINLSFVLGFIKEIFGLIWIRIYILIPILGVLIGLLVIVWLERKISAGIQQRIGPEYAGPLGILQALADGIKLLLKEDIIPSRGDLWLFSIGPAIVVIPILSSYLVIPFGRHIVLADLSIGVFFRIAVSSIAPLGLLMAGYGSNNKYSFSGGLRAAAQSISYEIPLALCVLSISLLSNSLGTVDIVEAQSRYGFWGWNLWRQPIGFIAFFISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYVASYLNLLASSLFVTILYLGGWNFSIPSIPISEYFEWDSINGTSEVLGITMGILITLAKAYLFLFISITARWTLPRMRIDQLLDLGWKFLLPIALGNLLLTASFQLLLL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SIGA_STAAW
Sequence: MSDNTVKIKKQTIDPTLTLEDVKKQLIEKGKKEGHLSHEEIAEKLQNFDIDSDQMDDFFDQLNDNDISLVNEKDSSDTDEKLNPSDLSAPPGVKINDPVRMYLKEIGRVNLLSAQEEIELAKRIEQGDEVAKSRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNMGLIKAVEKFDFNKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINKLIRVQRQLLQDLGRDPAPEEIGEEMDLPAEKVREILKIAQEPVSLETPIGEEDDSHLGDFIEDQEAQSPSDHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGKVFGVTRERIRQIEAKALRKLRHPSRSKRLKDFMD
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA2_STAAC
Sequence: MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKALGADIWTETV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_XANP2
Sequence: MARVKRGVTSHAKHKKVFEAAKGFYGRRKNTIRAAKSAVERSMQYAYRDRKVKKRNFRALWIQRINAGVRALDLDLTYSRFIDGLGKAGIEVDRKVLSDIAIHEPDAFKALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CARA_METVS
Sequence: MYGILVLEDGTIIRGKGFGAEAEVLGELVFNTSMTGYVEILTDPSYNGQIVTMTYPLEGNYGVDKRWFESEGIKAEGFIVKDMTGIELDSFLKEYGVPGISDVDTRFITKKIRSKGVVKSLLKTSATEISEEEEKELVNKVRNYEDISDIDLVPEVSTKKVVKYPAKDEKISCVVIDCGVKQSILNCLLERGCSVVKVPYDTKEEEILSYNPDFVLVSNGPGDPEKMLETANTVKNLFGKLPVTGICLGHQIITIALGGKTYKLKFGHRGGNQPVKDSSTGKVYITSQNHGFATDMSNVPEGSILSHVNLNDDTVEGISKIMDSDNVKGVVWSVQHHPEAGPGPHDAMFLFDDMVALGMKFKQEKTSKR
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: RL21_BRUSI
Sequence: MFAVIKTGGKQYRVAANDLIKVEKVAGEAGDIVEFAEVLMVGSTIGAPTVAGALVTAEVVEQGRGRKVIAFKKRRRQNSKRTRGHRQELTTIRISEILTDGAKPSKKAAEKKAPKADAAEGEAAKPKKAAPKKAAAKAESAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: FABH_YERE8
Sequence: MYTKILGTGSYLPVQVRSNADLEKMVDTSDEWIVTRTGIRERRIAGPDETVASMGFQAAKKALEMAVIDEGIDKKDIGLIIVATTSSSHAFPSSACQVQQMLGIEDAASFDLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDMLSRALDPEDRGTIILFGDGAGAVVLGASEEPGILSTHLHADGKYGELLALPYPDRQHQEQPAYVTMAGNEVFKVAVTELAHIVDETLQANNLDRSALDWLVPHQANLRIISATAKKLGMGMDKVVITLDRHGNTSAASVPAAFDEAVRDGRIQRGQLVLLEAFGGGFTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BTUC_SHISS
Sequence: MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWFTPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASAVLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FFSC6_GIBF5
Sequence: MPHKDLPIRPLVRAFDPVGPDTLGPPDLDFASLFRERNVPEDAPLTLYPEQLNVPWHTSLPWTRQSKWWVQGEAAGRDLVNRISADKASERGALPVEFMDERRKGKIDELVEDAVSCAVYLYPSSSPTRIELLTQALLLLFFHDDVMERGATQDDATVCDDFVTMIPKNKHMKRYFAEVLECDPILGPGLLRAIGLFVNAGRKKSPFKQDKYATLAEYLDYRRHDIAKPFMIAAIRFGSGVRQTPEETAPFAELEDLYVQHSILINDLYSYDKEMYEARTINGSVVNAVHVIEKLMCVPPHLAKTITRTMSFDVEKKYYAESERFMRDPALNDKQRTYVIALFDCLTGNLFHHATLGRYSRYAEYVFDCKT
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to the spirocyclic sesquiterpene alpha-acorenol.
What are the official names of this protein?
Terpene cyclase 6, Sesquiterpene synthase 6.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: PA2_HOFGE
Sequence: MSLIIVLVISVLSADAVLSMDNELYLNLEPSQRSSWPVARAVRMQFSKRSEGGRESRKMQGCQILESLNDIAREALRTPRHTTKRISKDEMEFFEGRCLSVGESERTVLGTKWCGAGNEAANYSDLGYFNNVDRCCREHDHCDNIPAGETKYGLKNEGTYTMMNCKCEKAFDKCLSDISGYFTRKAVSAVKFTYFTLYGNGCYNVKCENGRSPSNECPNGVAEYTGETGLGAKVINFGK
What is the function of this protein?
Toxic phospholipase A2, which may catalyze the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.  Inhibits both skeletal (RYR1) and cardiac (RYR2) ryanodine receptors (calcium release channels).  Probably blocks ryanodine receptors by generating a lipid product (By similarity).
What are the official names of this protein?
Phospholipase A2, HgPLA2, Group III heterodimeric phospholipase A2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRE_STAAN
Sequence: MAKEIAKSLLDIEAVTLSPNDLYTWSSGIKSPIYCDNRVTLGYPLVRGAIRDGLINLIKEHFPEVEVISGTATAGIPHAAFIAEKLKLPMNYVRSSNKSHGKQNQIEGAKSEGKKVVVIEDLISTGGSSVTAVEALKQAGAEVLGVVAIFTYGLKKADDTFSNIQLPFYTLSDYNELIEVAENEGKISSEDIQTLVEWRDNLA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: UB2V1_CAEEL
Sequence: MVDVPRNFRLLEELEEGQKGKGDGNISWGLEDDSDMTLTRWTASIIGPPRTPYESRIYNLQIQCGGNYPREPPTVRFTTKVHMVGVNQSNGVIDKRNLTTLRNWSNSYMIKTVLEDIRKNMMMAKENLKLQQPAEGAMF
What is the function of this protein?
Involved in protein ubiquitination, but has no ubiquitin ligase activity on its own (PubMed:15530417).  The uev-1-ubc-13 heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through Lys-63 (PubMed:15530417, PubMed:24595290).  Involved in sorting Lys-63-linked polyubiquitinated maternal membrane proteins for degradation by targeting to multivesicular bodies (PubMed:24595290).  Required for glr-1-containing glutamate receptor trafficking in neurons (PubMed:21179194).  May have a role in synaptic transmission at motorneurons (PubMed:21179194).  May be involved in the ubiquitination and growth of intracellular polyglutamine protein aggregates (PubMed:17663792, PubMed:22494772).
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 variant 1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Cell projection, dendrite. Perikaryon.