PharMolix/UniProtQA huggingface dataset:
Protein: M2_I80A8
Sequence: MSLLTEVETPTRNGWECKCSDSSDPLVIAASIIGILHLILWILDRLFFKCIYRRLKYGLKRGPSTEGVPESMREEYRQEQQNAVDVDDGHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: TM108_MOUSE
Sequence: MKRSLQALYCQLLSFLLTLALTKALVLAVHEPSPRESLQTLPSGSPPGTMVTAPHSPTRLSSVLTLNPTPDGPSSQAAATLETTVSHPEGHPPTDTTSTVMGTAAVPHPESPLPTGSPPAAMTTTPSHSESLPPGDATPTTTLPTKPAGTTSRPTVAPRATTRRPPRPPGSSRKGAGGSTRTLTPVPGGHLARKESQRGRNQSSAHLGPKRPLGKIFQIYKGNFTGSAEPDPSALTPRTPLGGYFSSTQPQTVSPATAPRSTSRVPPTTSLVPVKDKPGFIRSNQGSGPILTSPGGEPAATAATGAPASTQPAPVPSQSPHGDVQDSASHSDSWLAVTPDTDRPTSASSGVFTAATGPTQAAFDATVSAPSPGIPQGPSATPQAPTRPSGVSESTVSPAEEEAEASPTTTDRGPRPLSTVLSTATGNFLNRLVPAGTWKPGTVANISHVAEGDKPQHRATICLSKMDIAWVIVAISVPISSCSVLLTVCCMRRKKKTANPENNLSYWNNAITMDYFNRHAVELPREIQSLETSEDQLSEPRSPANGDYRDTGMVLVNPFCQETLFVGNDQVSEI
What is the function of this protein?
Transmembrane protein required for proper cognitive functions.  Involved in the development of dentate gyrus (DG) neuron circuitry, is necessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons (PubMed:28096412).  Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.  Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport (PubMed:17287360).  In hippocampal neurons, required for BDNF-dependent dendrite outgrowth (PubMed:21849472).  Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes (PubMed:21849472, PubMed:27605705).
What are the official names of this protein?
Transmembrane protein 108, Retrolinkin.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Postsynaptic density. Endosome membrane. Cell projection, axon. Cell projection, dendrite. Early endosome.
Protein: MTNC_ACICJ
Sequence: MTTRPELVLLDIEGTIAPISFVHDVLFPYARARLAGFVAAHGDEPEIAAALAELDAIAPGAPPVETLLALMDRDAKVGPLKLIQGRIWAEGFAEGALTSRLYPDVAPVLRAWHGSGLRLAIYSSGSEEAQRLLLGHTPDGGLTALFERFFDTRMGGKRDAASYAAIARSMAVAPAHVLFLSDVADELAAAATAGIQVCQIVRPEDGTIASADYPTAPDLAAVAAAFDRPDPA
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: TSDA_ALLVD
Sequence: MRGDVRVHTASPIAAAWLLAVGLVAHAEEPPTVALTVPAAALLPDGALGESIVRGRRYLSDTPAQLPDFVGNGLACRHCHPGRDGEVGTEANAAPFVGVVGRFPQYSARHGRLITLEQRIGDCFERSLNGRALALDHPALIDMLAYMSWLSQGVPVGAVVAGHGIPTLTLEREPDGVHGEALYQARCLACHGADGSGTLDADGRYLFPPLWGPRSFNTGAGMNRQATAAGFIKHKMPLGADDSLSDEEAWDVAGFVLTHPRPLFQEPTGD
What is the function of this protein?
Catalyzes the oxidation of 2 molecules of thiosulfate to tetrathionate.
What are the official names of this protein?
Thiosulfate dehydrogenase, Tetrathionate synthase.
What are the subcellular locations of this protein?
Periplasm.
Protein: CYSK2_ORYSJ
Sequence: MAESGQSIASDVTALIGNTPLVYLNKVVDGCEAQIAAKLEIMEPCSSVKDRIGYSMITDAEEKGLITPGKSVLIEPTSGNTGIGLAFMAAAKGYKLILTMPASMSMERRIILKAFGAELVLTDPLLGMKGAIQKADELAAKMPNSYILQQFENPANPKIHYETTGPEIWKATAGKVDILVSGIGTGGTVTGTGKYLKEQNPEIKIYGVEPTESAILSGGRPGPHKIQGIGAGFVPGVLDVNLLDEVVQVSSDEAISMAKQLALKEGLLVGISSGAAAVAAIRVAQRPENKGKLVVVVFPSFGERYLSSVLFESIKREAENMVFEP
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHI_SYNJA
Sequence: MTFLKRVGEYVSDAFKAAKYIGQGMGVVFDHMNRRPVTVQYPFEKLIPSERFRGRIHFEFDKCIACEICVRVCPIDLPVVDWVYNTELKKKELYSYSIDFGVCIFCANCVEFCPTNCLSVTEDYELATYDRHELNYHQVALGRLPSKVTEDPMVTPLREFAYLPKGVIDPHDLPTGSQRAGKRPEEILAEMRAAKAAEAKEDKTAAEQSN
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: Y167_UREPA
Sequence: MKVELYTNDWIDFFKNIAIAWFKTKRYGNKRLSSIEQKQVNKLIRQEFDQYVEFKIISNLIKDYNDNMEKVISLYGANLMPLNLAVQKLYPELTPTEQDELVKELEHKQKLENGEFENE
What are the official names of this protein?
Uncharacterized protein UU167.
Protein: RS12_STRS7
Sequence: MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DHE3_PYRFU
Sequence: MVEQDPYEIVIKQLERAAQYMEISEEALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQHNWARGPTKGGIRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAIYDVISPYEDIPAPDVYTNPQIMAWMMDEYETISRRKTPAFGIITGKPLSIGGSLGRIEATARGASYTIREAAKVLGWDTLKGKTIAIQGYGNAGYYLAKIMSEDFGMKVVAVSDSKGGIYNPDGLNADEVLKWKNEHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIKAKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYWTIEEVRERLDKKMTKAFYDVYNIAKEKNIHMRDAAYVVAVQRVYQAMLDRGWVKH
What are the official names of this protein?
Glutamate dehydrogenase, GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_LEPIC
Sequence: MASIKPLGDRVLVEPRQEAEEKIGSIFVPDTAKEKPQEGKVVEIGSGKYEDGKLIPLEVKVGDTVLYGKYSGTEIKSEGKEYLIIRESDILAVVKK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY550_PARPN
Sequence: QEGDAAKGEKEFNKCKACHMVQAPDGTDIVKGGKTGPNLYGVVGRKIASEEGFKYGDGILEVAEKNPDLVWTEADLIEYVTDPKPWLVEKTGDSAAKTKMTFKLGKNQADVVAFLAQNSPDAGAEAAPAEDAAD
What is the function of this protein?
Electron donor for nitrous-oxide reductase.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c550.
Protein: DRC10_MOUSE
Sequence: MALDQVSIPPSYHGLAIQRIPLRTGLVPAEPMKTLVPSKSKLNTIEAKRIMSVLDEAIHKIELITLMSYMESHPEALEDTLPEDFVRALREHLDIGQTLVERASILQRRHKKLEEEEEAEETRNQERLLSLELHKVNLLTLAHQFRDSTKTVLRLVLGEPQFTRLLQVQAPGRSPGAQCLLDGLVELRGFLFEKLLTSPMEVREKNQFIQDISRRSERNQEVIDDLQAELANVLKNKESEVEKENFVIQELKNHLHQVFKFSENSLLRTKQEAEKQQKVDFRASQVRLAKTQQDILALRAQYHNLVMENREAEQALRKKKYKVETEIENWIQKYDMEMGEKQDEYEDLESIHKEEKLQLEELRERHAVLVEEFSQIRAESEINSKKRVEAEREMVRMVRAATLIQAVWKGYLVRSILRSKKKKRGKGKGKDKGKGKEKPKEEKAKEKKPKAKGKGKKK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
What are the official names of this protein?
Dynein regulatory complex protein 10, IQ domain-containing protein D.
What is the protein family that this protein belongs to?
Belongs to the DRC10 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: ASZ1_EULMM
Sequence: MASGALRGLAVAGGGESSDSEDDGWEIGYLDRVSQKLKGPLPGEEKSETFKKALTTGDISLVQELLDSGISVDSSFRYGWTPLMYAASIANVELVRVLLNRGANASFDKDKQTILITACSARGSEEQILKCVELLLSRNADPNIACRRLMTPIMYAARDGHPQVVALLVAHGAEVNAQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKDGKIPSEIAKRNKHLEIFNFLSLTLNPLEGNLKQLTKEETICKLLTTDSDKEKDHIFSSYTAFGDLEIFLHGLGLEHMTDLLKEKDITLRHLLTMRKDEFTKNGITSKDQEKILSALKELEVEEIKFGELPEVAKLEISGDEFLNFLLKLNKQCGHLITAVQNIITELPVNSHKIVLEWASPRNFTSVCEELVSNVEDLSEEVHKLKDLIQKLQNERENDPTHIPLMEEVSTWNSRILKRTAIAVCGFGFLLFICKLTVQRRYPNICF
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: FAR2_TYRGL
Sequence: ADYLRLARA
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-2, FMRFa-2.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YCLH_BACSU
Sequence: MSLLQFQQVGYWYKNKSQPLFQDINISFQKGKFYTIVGTSGTGKTTFLSLAGGLDAPKEGNILYDGKAVSKIGLTNFRNQYVSIVFQAYNLLPYMTALQNVTTAMEITGSKEKNKESYALDMLQKVGINEKQARQKVLTLSGGQQQRVSITRAFCCDTDLIVADEPTGNLDEDTSKEIVRLFQDLAHKEDKCVIMVTHDEQIAKVSDINIRLSRGSFTVKENVAVV
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YclH.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: YSCJ_YERPS
Sequence: MKVKTSLSTLILILFLTGCKVDLYTGISQKEGNEMLALLRQEGLSADKEPDKDGKIKLLVEESDVAQAIDILKRKGYPHESFSTLQDVFPKDGLISSPIEELARLNYAKAQEISRTLSEIDGVLVARVHVVLPEEQNNKGKKGVAASASVFIKHAADIQFDTYIPQIKQLVNNSIEGLAYDRISVILVPSVDVRQSSHLPRNTSILSIQVSEESKGHLIGLLSLLILLLPVTNLAQYFWLQRKK
What is the function of this protein?
Required for the export process of the Yop proteins.
What are the official names of this protein?
Yop proteins translocation lipoprotein J, Lipoprotein YlpB, Low calcium response locus protein KA.
What is the protein family that this protein belongs to?
Belongs to the YscJ lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MDTN_SHIFL
Sequence: MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYASADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQIMLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTAQRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMTTVRAPFDGRIISLKTSVGQFASAMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGASAVANLEPQ
What is the function of this protein?
Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride.
What are the official names of this protein?
Multidrug resistance protein MdtN.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: NADD_SULDN
Sequence: MDTIALFGGSFDPPHIGHEAIIEALKKFKDIDKIIIMPTFLNPFKSNFYAPSSLRVKWLREIFKEEKRVEVSDYEVLQNRQVPTIETAKHLLESYKKIYLVIGADNLAKLRDWNSYDELKELVTFVVATRDDIEIPDEFIMLSVDEKISSTQLRENIQLSKLPKKCAKEIYDFYKEEHCKTE
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: Y411_STAAC
Sequence: MASLKNKHFMIGLSLTFIVALFSFLAAKLPILDKVGALTIAILIAILYRHFRGYPEQYSSGITFSSKYLLRFAIILYGLKLNIFDIIGQGSKLLAIDVGVVIFSIVMMLFVNKLLHGDKNIALLLGVGTGVCGAAAIAAVAPIFKSREKDTAISIGIIALIGTIFSLIYTAIYAIFSMTTNVYGAWSGVSLHEIAHVVLAGGFGGSDALKIALLGKLGRVFLLIPLTIVLILIMRFRSSESSSKGRISIPYFLIGFVIMALVNTYVTIPSALLNILNTVSTICLLMAMVALGLNVAFKDLKNRALKPLMTIIITSICLSSLAFIVVHWLYS
What are the official names of this protein?
UPF0324 membrane protein SACOL0411.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VES_ECOBW
Sequence: MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIAANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPFQPFAFAADQVVKAKLTAGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFDGRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
What are the official names of this protein?
Protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.
Protein: ECHA_MOUSE
Sequence: MVASRAIGSLSRFSAFRILRSRGCICRSFTTSSALLTRTHINYGVKGDVAVIRINSPNSKVNTLNKEVQSEFIEVMNEIWANDQIRSAVLISSKPGCFVAGADINMLSSCTTPQEATRISQEGQRMFEKLEKSPKPVVAAISGSCLGGGLELAIACQYRIATKDRKTVLGVPEVLLGILPGAGGTQRLPKMVGVPAAFDMMLTGRNIRADRAKKMGLVDQLVEPLGPGIKSPEERTIEYLEEVAVNFAKGLADRKVSAKQSKGLVEKLTTYAMTVPFVRQQVYKTVEEKVKKQTKGLYPAPLKIIDAVKAGLEQGSDAGYLAESQKFGELALTKESKALMGLYNGQVLCKKNKFGAPQKNVQQLAILGAGLMGAGIAQVSVDKGLKTLLKDTTVTGLGRGQQQVFKGLNDKVKKKALTSFERDSIFSNLIGQLDYKGFEKADMVIEAVFEDLGVKHKVLKEVESVTPEHCIFASNTSALPINQIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTDKTSKDTTASAVAVGLRQGKVIIVVKDGPGFYTTRCLAPMMSEVMRILQEGVDPKKLDALTTGFGFPVGAATLADEVGVDVAQHVAEDLGKAFGERFGGGSVELLKQMVSKGFLGRKSGKGFYIYQEGSKNKSLNSEMDNILANLRLPAKPEVSSDEDVQYRVITRFVNEAVLCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKVVDRLRKYESAYGTQFTPCQLLLDHANNSSKKFYQ
What is the function of this protein?
Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway.  The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA.  Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids.  Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA described here carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities while the trifunctional enzyme subunit beta/HADHB bears the 3-ketoacyl-CoA thiolase activity.  Independently of the subunit beta, the trifunctional enzyme subunit alpha/HADHA also has a monolysocardiolipin acyltransferase activity.  It acylates monolysocardiolipin into cardiolipin, a major mitochondrial membrane phospholipid which plays a key role in apoptosis and supports mitochondrial respiratory chain complexes in the generation of ATP.  Allows the acylation of monolysocardiolipin with different acyl-CoA substrates including oleoyl-CoA for which it displays the highest activity.
What are the official names of this protein?
Trifunctional enzyme subunit alpha, mitochondrial, Monolysocardiolipin acyltransferase, TP-alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Note=Protein stability and association with mitochondrion inner membrane do not require HADHB.
Protein: PYRG_WOLSU
Sequence: MSESKKNPETKYIFVTGGVLSSLGKGITSSSVATLLKHSGFNVGILKIDPYINVDPGTMSPFEHGEVFVTYDGAETDLDIGHYERFLNTNFSSKHNFTTGQVYLSVIERERRGGYLGKTIQVIPHIVDEIKHRVRLAGEGKEFLVVELGGTVGDIEGLPFLEAMREMKHELGLERVISVHVTLIPLIKAAGELKTKPTQHSVQELRRIGITPQIIIARSEKPLPKELKKKLSLGCDVDYDSVIVAEDAPTIYQVPLNFMKEDILTPIARRFNMPKIEPKMEEWNRLVKQILAPKDEVTIAFVGKYLSLKESYKSLIEALTHAGANLDTKVNIKWCDSEEIESSGVEPLRYVDGILVPGGFGERGVKGKMEAIRFARENKIPFLGICLGMQLAMIEFARNVLGIAEANSMEFDPQTPEPIIYLIEDFIDQQGNKQVRTHTSPMGGTMRLGEYECGLKEGSQTKAAYQGESLIKERHRHRYEANPKYRERIEQAGLIVSGESEGLIEALELVDHPWFIGVQFHPEFTSRLQNPNPVILTFIQKSLELKKVDRDS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: EIF3C_XENLA
Sequence: MSRFFATGSDSESESSLSGDEILPKPVGGTFGKQPIILSDDEEDTKRVVRSAKDKRFEELTNLIKTIRNAMKIRDMTKCLEEFELLVKAFIKAKNIVDKEGVPRFYIRLLSDLDDYLNELWEDKEGKKKMNKNNAKALSTLRQKLRKYNRDFEASITAYKQNPEESADEDQEKDEDSEASSSSDDDSDEGMSASKFLKKAESAPPESRSKFLKKEEAEDEAESSEDEDWGSDSDESDSDESDDENKHASMASRFLKKTVTEGDRQAVEKKKEDKAKKKQHRKVKRKDEEGEEGEEDDNEGGGEWEKVKGGVPLVKEKPKMFAKGTEITPPIVVKKLNEILLARGKKGTDRAAQIELLQLLAGIAEENNLGQGIAVKIKFNIMASLYDYNTNLATYMKSDMWKKCLDCIHDLLDILFANSNMFIGEHIVEDSENLSNLEQPLRVRGCILTLIERMEEEFTKIMQNTDPHSQEYVDNLKDEARVCEVIERAQKYLQEKGSTEEICRVYLRRIMHTYYKFDYKAHQRQLSTEQESKSEQDQAENEAEDSAILMDRLCKYIYAKDRTDRIRTCAILCHIYHHALHNRWFQARDLMLMSHLQDNIQHADPPVQILYNRTMVQLGICAFRQGMIRDAHNALLDIQSSGRAKELLGQGLLMRTMQERNQEQEKIEKRRQIPFHMHINLELLECVYLVSAMLLEIPYMAAHEFDARRRMISKQFHHQLRVGERQPLLGPPESMREHVVAASKAMKMGDWKTCKNFIINEKMNGKVWDLFPEAERVRGMLVRKIQEESLRTYLFTYSSVYDSIRMGILGDMFQLEIPTVHSIISKMIINEELMASLDQPTQTVVMHGTEPSSLQNTALQLAEKLGNLVENNERIFDHKQGSYGGYFNRGDRGDRGDRDQKDQYQRKEGGYMRRGYRRDQQGQSNY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYAM1_RAT
Sequence: MVFPWRCQSAQRGSWSFLKLWIRTLLCCDLLPHHGTHCWTYHYSERSMNWENARKFCKHNYTDLVAIQNKREIEYLEKTLPKNPTYYWIGIRKIGKTWTWVGTNKTLTKEAENWGTGEPNNKKSKEDCVEIYIKRERDSGKWNDDACHKRKAALCYTASCQPESCNRHGECVETINNNTCICDPGYYGPQCQYVIQCEPLKAPELGTMNCIHPLGDFSFQSQCAFNCSEGSELLGNAKTECGASGNWTYLEPICQVIQCMPLAAPDLGTMECSHPLANFSFTSACTFTCSEETDLIGERKTVCRSSGSWSSPSPICQKTKRSFSKIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKKGKKSQERMDDPY
What is the function of this protein?
Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells.  Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes.  Promotes initial tethering and rolling of leukocytes in endothelia.
What are the official names of this protein?
L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, Lymphocyte antigen 22, Ly-22, Lymphocyte surface MEL-14 antigen.
What is the protein family that this protein belongs to?
Belongs to the selectin/LECAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MRAZ_PSET1
Sequence: MFRGASSLSLDDKGRFAVPTKYRDDLLSEDQGTVICTVALNEPCLWLYPLAQWQEIESRLAKISNMNPRARRMQRMLLGNATEYQLDKNGRILLAPSLRAHADLGKKIMLVGLMNKFEIWDEARWHQQMRQDTELERLGDFEPHPDLDNFTL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.