PharMolix/UniProtQA huggingface dataset:
Protein: FETP_PSEAB
Sequence: MSRTVMCRKYHEELPGLDRPPYPGAKGEDIYNNVSRKAWDEWQKHQTMLINERRLNMMNAEDRKFLQQEMDKFLSGEDYAKADGYVPPSA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: PGK_SYNR3
Sequence: MAKRSLSALNSDALRGKRVLVRVDFNVPLNDAGAITDDTRIRAALPTIKDLTGKGAKVILSAHFGRPKGQVNEDMRLTPVAARLSELLGAPVAKTDSCIGSDAEAKVAAMADGDVVLLENVRFFAEEEKNESGFAEKLAALAEVYVNDAFGAAHRAHASTEGVTKYLSPSVAGYLMEKELQYLQGAVDDPKRPLAAIVGGSKVSSKIGVLEALIDKCDKVLIGGGMIFTFYKARGLSVGKSLVEEDKLELAKELEAKAKAKGVQLLLPTDVVLADNFAPDANSQVASIDAIPEGWMGLDIGPDSIKVFQDALGDCKTVIWNGPMGVFEFDKFAAGTNAIATTLAELSAKGCCTIIGGGDSVAAVEKAGLAAQMSHISTGGGASLELLEGKVLPGVAALDEAA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXA_ECOL5
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RRBR2_CLOAB
Sequence: MKKFKCVVCGYIYTGEDAPEKCPVCGAGKDKFVEVKDEGEGWADEHKIGIAKGVDKEVLEGLRANFTGECTEVGMYLAMARQADREGYPEVAEAYKRIAFEEAEHASKFAELLGEVVVADTKTNLQMRVDAEKGACEGKKELATLAKKLNYDAIHDTVHEMCKDEARHGSAFRGLLNRYFK
What is the function of this protein?
Functions as the terminal component of an NADH peroxidase (NADH:H(2)O(2) oxidoreductase) when using NADH:rubredoxin oxidoreductase (NROR) as the electron transport intermediary from NADH to revRbr 2.  Plays an important role in the oxidative stress defense system in C. acetobutylicum, an obligate anaerobic bacterium.  Also exhibits NADH oxidase (NADH:O(2) oxidoreductase) activity in vitro, which is 100-fold lesser than that of FprA1/2 using the same electron transfer components.  Therefore, its predominant function is most likely as a scavenger of its preferred substrate, H(2)O(2).
What are the official names of this protein?
Reverse rubrerythrin-2, revRbr 2, NADH peroxidase, NPXase, Npx, Rubperoxin 2, Rpr 2.
Protein: CSE15_BACSU
Sequence: MKRSGPFFHDVSQENLYLKSELSRCHKLISELEASYFHQKNNKLLKENTDMKEKLQQLSAELTHMSTKEKHASHTSQTLHQIRAELLDKIVVLQELLSAETYKRRAEIEEKHKLHIAKVKIEEENKNLHKRISELQASIEQEQNALLQAKQQAELIKAENGRLKEQMVEKEYQLKHIKIEVDHMKDRIIETKERLLDIEKTKEKLFHETIISYKRQLDESDAWIASHFADIDGGTKQKEKTEEEAPAAYAQPNHVETILEDVTKQIHVLQKQLAHAQSSDQAKSHTIEELKNRAAEEKPYQKWVYKLNLEKENKPSQKKPQ
What are the official names of this protein?
Sporulation protein cse15.
Protein: MNMA_CHLTE
Sequence: MSSPQHVIIGLSGGVDSAVAACLLIKQGYHVTGLNIRVLDTPEDTPTLAPSAMRISDSEEFDFPVFTLNLSAKFARDVVGYFHDDYLAGRTPNPCMVCNKAIKWFGLFEAMRLLRADLVATGHYARTELRDAVTRLLKGVDPEKDQSYFLWMLTQAELAKTLFPLGGYTKAEVRELARSFGVHAAEKKESQEICFVPHDDYCAYLANAIPGLEARVAGGEIVDQAGKVIGHHRGYPFYTIGQRRGLGVSTGEPVYVTEIDAEHNRIHVGSKADLECRSLIASGMNWIGIATPDKSFEAEARIRYRDRQSACMIEPMDDNRAWVSFREPKQGVACGQAVVFYDGDEVLGGGIIAKVNPEAPPQKILG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGK3_CAEEL
Sequence: MLLSPEQFSRLSEYAAYSRRKLKDMLSDFQQDGKFYSYLSVDGQTINIDGFRAFLIDYFGADLPSDLVDQLFLSFSKPPIKERRTSLFEDAISTVRAKFSESLSGRMAGLNIAGGSGQQTDRSQSSEPQALVCIPEDDVMGPRVANNDSQEPRIPLKPLICTLSLLEADTPENKLDVVFHVYDSDGNGFLDKSEIDGIIEQMMNVARYQQWDTIELEQVIRQMMVDIDYDNDGIVSFDEWRRGGLTNIPLLVLLGFDTEMKEDGSHVWRLRHFTKPTYCNACCSILVGWGGKQGLSCSLCKYTVHERCVRSAATNCIRTYSSRQQDKLYHHWQDANATAKCVKCKATVGVFQGKGCRWCHNYVHHRCMSALAQECDLGALVHHILPPTHIFPAFLERKTSTSLKNHNFSSHSASLLQAVSPSNDCRPLLVLVNPKSGGKQGVKILQKFEYLLNPRQVYDLSKTGPEPGLQLFSTLKNCNILVCGGDGTIGWVLESMDKMTFPHGRPPVAVLPLGTGNDLARCLRWGGGYENENLHKILEQIEKSSLIDMDRWQIKIEITENKSARRASEKGDTPPYSIINNYFSIGVDASIAHRFHVMREKFPEKFNSRMRNKLWYFELGTSETLSSSCKNLHEQIDILCDGESIDLGQDASLEGIALLNIPSIYGGSNLWGRSRKSKGRMPGLFPMKNAEKMQLQTRVQDIGDGLIELVGLESAMQMGQIKAGVRGARRLSQCSTVVIQTHKSFPMQIDGEPWMQPPCIIQITHKNQAKMLVAAAPRKRSSWMLLKRQSTNDDN
What is the function of this protein?
Involved in AFD-neuron mediated thermotaxis.  Regulates behavior to environmental temperature.  Thought to have a role in olfactory adaptation by affecting diacylglycerol levels.
What are the official names of this protein?
Probable diacylglycerol kinase 3, DAG kinase 3, Diglyceride kinase 3, DGK-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
Protein: HOP2_HUMAN
Sequence: MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKIYFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAELKELSSALTTPEMQKEIQELKKECAGYRERLKNIKAATNHVTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP
What is the function of this protein?
Plays an important role in meiotic recombination.  Stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis.  The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA.  This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA.  This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing.  May inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.  Acts as a tissue specific coactivator of hormone-dependent transcription mediated by nuclear receptors.
What are the official names of this protein?
Homologous-pairing protein 2 homolog, Nuclear receptor coactivator GT198, PSMC3-interacting protein, Proteasome 26S ATPase subunit 3-interacting protein, Tat-binding protein 1-interacting protein, TBP-1-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the HOP2 family.
Protein: RS8_NAUPA
Sequence: MMNDIIADGLTRIRNAAMRGLEVTQLNHSKLMEAVLKVFEDKGYIESFKVVEDGNKKFINVTLKYDENGNSVINEVKKVSKPGRRVYKGYEDIKRFKNGYGTLVVSTNKGVLPNDEAYKLKVGGEVICSIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: APT_CHLTE
Sequence: MPIKSRIRTVPDYPKKGIMFRDITTLIKDPVGFRLVIDNMTQHYLSNGVDFDAIVGIESRGFILGGALAYTLGKGFVPVRKPGKLPADVVQLEYELEYGTDKIEMHTDALVQGQRVLLVDDLLATGGTALAAAGLVEKLGGVVASMAFIVNLPDIGGEKKIREKGYNIYFLTEFEGD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPR_CROS8
Sequence: MTQHSTYSAAQAEQSNQEWLRFVALLKQSFDNDLHLPLLTLLLTPDERAALGTRVRIIEELLRGEMSQRELKSELGAGIATITRGSNSLKAAPPELRQWLEQELLQAQR
What is the function of this protein?
This protein is an aporepressor.  When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription.  The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
What are the official names of this protein?
Trp operon repressor.
What is the protein family that this protein belongs to?
Belongs to the TrpR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_META1
Sequence: MLDLKFILNNKNEVIKKLSTRNYDLANITKINNLGEMRSKLIFELEKLQAKRNKLSDEIGIKKRNNENCDSLIEEVNAIKAQIEKVDHEADDIISQVNDILTKIPNLPYDDVPVGSDELDNKVIKEHASLGRGLVKGVEAHYDIATKLDIIDFTRAVKLAQTRFVLYKNAGAKLIRALANFMLDTHINNGYKEIMPAHLVNSKMLFGTGQLPKFKDDLFRVSDSDLWLIPTAEVPLTNYHYDEILNLNEPIKYVAYTKCFRSEAGSGGRDTRGIIRQHEFHKVELVKIVRQEDAMGEWEKMVNDAKNILTLLELPYREILLCTGDMGFSSAKTIDLEIWIPSEQRYRETSSISICKDFQARRAKIRYKDADGKTKYAFTMNGSGVAIDRVMAAILENYQNSDGTITVPKVLVPYMNGITKIEAK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1267_BORBR
Sequence: MNIWVDADACPAEVKDILWRAAQRWQVPVTLVANQLLRVPASPWMRAVQVPRGFDVADAHIVASAVPGDLVITADIPLAAEVVGKGVAAMSWRGEVFDAGSIGERLTMRDMMEELRAGGVDIGGPAAFGQADRRAFANALDAAMQRRARTRGAGGKPGVV
What are the official names of this protein?
UPF0178 protein BB1267.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: KDPA_MYCBO
Sequence: MSGTSWLQFAALIAVLLLTAPALGGYLAKIYGDEAKKPGDRVFGPIERVIYQVCRVDPGSEQRWSTYALSVLAFSVMSFLLLYGIARFQGVLPFNPTDKPAVTDHVAFNAAVSFMTNTNWQSYSGEATMSHFTQMTGLAVQNFVSASAGMCVLAALIRGLARKRASTLGNFWVDLARTVLRIMFPLSFVVAILLVSQGVIQNLHGFIVANTLEGAPQLIPGGPVASQVAIKQLGTNGGGFFNVNSAHPFENYTPIGNFVENWAILIIPFALCFAFGKMVHDRRQGWAVLAIMGIIWIGMSVAAMSFEAKGNPRLDALGVTQQTTVDQSGGNLEGKEVRFGVGASGLWAASTTGTSNGSVNSMHDSYTPLGGMVPLAHMMLGEVSPGGTGVGLNGLLVMAILAVFIAGLMVGRTPEYLGKKIQATEMKLVTLYILAMPIALLSFAAASVLISSALASRNNPGPHGLSEILYAYTSGANNNGSAFAGLTASTWSYDTTIGVAMLIGRFFLIIPVLAIAGSLARKGTTPVTAATFPTHKPLFVGLVIGVVLIVGGLTFFPALALGPIVEQLSTQ
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH60_BARBA
Sequence: MAAKEVKFGRDARERLLRGVDILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVSVAKEIELENKFENMGAQMLREVASKTNDIAGDGTTTATVLGQAIVQEGVKAVAASMNPMDLKRGIDAAVEAVVADLFKKAKKIQTSEEIAQVATISANGAEDIGKMIADAMEKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNSEKMMVDLDDPYILIHEKKLSNLQSLLPVLEAVAQSGKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAVLTSGQVISEDVGIKLENVTLEMLGRAKKVHVSKETTTIVDGAGQKSEINARVSQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGSTEVEVKEKKDRVDDALNATRAAVEEGIVPGGGTPLLRAAKALSIKGKNPDQEAGIGIIRRALQAPARQIAHNAGEEAAVIVGKVLENCSDTFGYNTATAQFRDLISFGIVDPVKVVRSALQNAASIASLLITTEAMVAEVPKKEAAAPAMPGGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1B1_CAVPO
Sequence: MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISELKPTYQDRVAPPGLTQIPQIQKTEISFRPADPKSYEAYVLNIYRFLEKYKDAAQKDDMIFEDCSTVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGQNDDSYGYRDGKPCIIIKLNRVLGFKPKPPKNDSSETVEIYSTMKYNPYVLPVQCTGKREEDKDKIGSVEYFGLGGYAGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTTDTEVRIECKAYGENIGYSEKDRFQGRFDVKIEVKS
What is the function of this protein?
Involved in cell adhesion and establishing epithelial cell polarity.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Cell membrane, sarcolemma. Note=Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes. Localizes in long striations at the level of Z and M lines.
Protein: PBP1_EPIPO
Sequence: MMNHKELVLFAVVCLSLYQAVEPSQDVVKDMSLNFRKGLDACKKELNLPDTINADFNRFWNDDHVVTNRDTGCAIMCLSSKLELVTDTGLHHGNTLEYAKQHGADETVAQQIVDLLHTCAQAVPDLQDTCMKVLEWAKCFKAEIHKLNWAPSAEVMAAEMLAEV
What is the function of this protein?
This major soluble protein in olfactory sensilla of male moths serves to solubilize the extremely hydrophobic pheromone molecules such as bombykol and to transport pheromone through the aqueous lymph to receptors located on olfactory cilia.
What are the official names of this protein?
Pheromone-binding protein 1, PBP 1.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
Protein: PLCD4_ARATH
Sequence: MEGKKEMGSYKFCLIFTRKFRMTESGPVEDVRDLFEKYTEGDAHMSPEQLQKLMTEEGGEGETSLEEAERIVDEVLRRKHHIAKFTRRNLTLDDFNYYLFSTDLNPPIADQVHQNMDAPLSHYFIFTGHNSYLTGNQLSSNCSELPIADALRRGVRVVELDLWPRGTDDVCVKHGRTLTKEVKLGKCLESIKANAFAISKYPVIITLEDHLTPKLQFKVAKMITQTFGDMLYYHDSQGCQEFPSPEELKEKILISTKPPKEYLEANDTKEKDNGEKGKDSDEDVWGKEPEDLISTQSDLDKVTSSVNDLNQDDEERGSCESDTSCQLQAPEYKRLIAIHAGKPKGGLRMALKVDPNKIRRLSLSEQLLEKAVASYGADVIRFTQKNFLRIYPKGTRFNSSNYKPQIGWMSGAQMIAFNMQGYGRALWLMEGMFRANGGCGYVKKPDFLMDASPNGQDFYPKDNSSPKKTLKVKVCMGDGWLLDFKKTHFDSYSPPDFFVRVGIAGAPVDEVMEKTKIEYDTWTPIWNKEFTFPLAVPELALLRVEVHEHDVNEKDDFGGQTCLPVSEIRQGIRAVPLFNRKGVKYSSTRLLMRFEFV
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
What are the official names of this protein?
Phosphoinositide phospholipase C 4, Phosphoinositide phospholipase PLC4, AtPLC4, PI-PLC4.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein.
Protein: EIF3L_HUMAN
Sequence: MSYPADDYESEAAYDPYAYPSDYDMHTGDPKQDLAYERQYEQQTYQVIPEVIKNFIQYFHKTVSDLIDQKVYELQASRVSSDVIDQKVYEIQDIYENSWTKLTERFFKNTPWPEAEAIAPQVGNDAVFLILYKELYYRHIYAKVSGGPSLEQRFESYYNYCNLFNYILNADGPAPLELPNQWLWDIIDEFIYQFQSFSQYRCKTAKKSEEEIDFLRSNPKIWNVHSVLNVLHSLVDKSNINRQLEVYTSGGDPESVAGEYGRHSLYKMLGYFSLVGLLRLHSLLGDYYQAIKVLENIELNKKSMYSRVPECQVTTYYYVGFAYLMMRRYQDAIRVFANILLYIQRTKSMFQRTTYKYEMINKQNEQMHALLAIALTMYPMRIDESIHLQLREKYGDKMLRMQKGDPQVYEELFSYSCPKFLSPVVPNYDNVHPNYHKEPFLQQLKVFSDEVQQQAQLSTIRSFLKLYTTMPVAKLAGFLDLTEQEFRIQLLVFKHKMKNLVWTSGISALDGEFQSASEVDFYIDKDMIHIADTKVARRYGDFFIRQIHKFEELNRTLKKMGQRP
What is the function of this protein?
(Microbial infection) In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit L, eIF3l, Eukaryotic translation initiation factor 3 subunit 6-interacting protein, Eukaryotic translation initiation factor 3 subunit E-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit L family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_SALDC
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLANELERWKQDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_DESHY
Sequence: MLDLKFVRTNPEVVKEALKKRNSNVSLDAFLEQEEERRKLLFEVESLKAKRNTVSEEVGRRKKHGEDAEQLILEMREVGQKVKNLEDKLGEIEQSMEAVLYEIPNIPHESVPVGADEEANVEVRTWGTPRSFDFEPLAHYEIGEKLDILDFARAGKVTGARFTFYKGLGAKLERALISFMLDRHSAKGYVEVLPPYMVHRNSMIGTGQLPKFEEDAFKVAGTDYFLIPTAEVPVTNMYREEILEAEQLPIHHCAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFAFPENSYEELESLTRDAESILQELELPYRVMALSTGDLGFTSAKTYDLEVWLPSFNTYREISSCSNFEDFQARRANIRFRRAPKAKPEFLHTLNGSGLAIGRTVSAILENYQEADGRVRVPKALQPYLGVEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA47C_HUMAN
Sequence: MGDQRPQDRPSSPGMDSTPWYCDKPPSKYFAKRKHRRLRFPPVDTQNWVFVTEGMDDFRYGCQSPEDTLVCRRDEFLLPKISLRGPQADPKSRKKKLLKKAALFSKLSPAQPARKAFVEEVEAQLMTKHPLAMYPNLGEDMPPDLLLQVLKPLDPERKLEDAGSCEGQEKTTDEPTEPGKYPCGEFSPRPPETRVSCLPPEPPKTPVSSLRPEPPETGVSHLRPQPPKTQVSSLHLEPPETGVSHLRPEPPKTQVSSLHLEPPETGVSHLYLEPPGTGVSHLCPEPPKTRVSHLHREPPETGVPDLCLEPPKSRVSHLRPEPSETGVSHLHPEPPKTLVSSLHPEPPETGVSHLCPEPPETRVSPLRQLPPEAGVSHLCPEPPKTRVPPLRPETPKNGVSPLFPEPPKTRISNLRSEPPKIGVSHLCLEPPKTRGSHLRPEPPETGVSHLRPEPPKTRVSSLHLEPPETGVSHLCPEPPEKDVSHLRPEPPDTGVSHLCPEPPKTRVSHLRPEPSETGVSHLRPEPPKILVSSLHQAPPESSVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPDTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSHLRPEPPKTRMYSLRPEPPNTGVSHLCPEPPKTRVSSLPPEPPETGVSHLCPEPPETRVSHLRPEPPETGVSRLHPEPPKTRVSSLHAEPPESRVSHLCPEPPETGVSHLRPEPPKPRVSSLRPEPLETRVSHLRPEPPETGVSHLHPELPKPRVSSLHLEPPKTRRVSSLRLEPPKTGRVSSLCPEPTKTGASHLKELFQEGTSSTMECVSDSLQRRHTSRKLRDFKWAGDLGVNEESISSLFDFTPECRATYQDQKNKKANECSSGLKYSMELDEMDEVKFFSQEKDLDGKIQNAPNSHSAQHVKMGYGAWYLKPKLGKKLRSDEPLIDPKLVLEKPDEPDILDGLYGPIAFKDFILSKGYEMPGIIQRLFARRGWTYDSVKTPIQRAMQVYKYKEDVTDASEED
What are the official names of this protein?
Putative protein FAM47C.
What is the protein family that this protein belongs to?
Belongs to the FAM47 family.
Protein: Y406_BACAH
Sequence: MDLSVKSEENVEYMVEAIKEKLRMVNAGAMRAASFNEEMYEDLRDIYEHVMKRETFSISEMQAITEELGTLIKK
What are the official names of this protein?
UPF0435 protein BALH_0406.
What is the protein family that this protein belongs to?
Belongs to the UPF0435 family.
Protein: GUAA_GEODF
Sequence: MSVDIHSEKILILDFGSQYTQLIARRVREAHVYCELHPFDLELAAIRSFAPSGIILSGGPKSVYEEGAPAVAEELFELGVPVLGICYGMQLMSRHFGGEVVPAGKREFGHAELLAQGTPGPLFDGFFLDGKSPVWMSHGDHVSQVPEGFQVAAGTANAPVCAIQNLACNLYGVQFHPEVNHTPRGEQLIDTFVRKICGCSGKWTPGQIIEDAVARIKQQVGSDRVILGLSGGVDSSVAAALIHRAIGEQLTCVFVDNGLLRLGEGDQVMATFAQNLGVKVIRVDAEDRFLSALAGVSDPEKKRKIIGGLFVEIFEEESNKITDARWLAQGTIYPDVIESAGAKTGKAHNIKSHHNVGGLPEHMKLKLLEPLRELFKDEVRAIGEELGLPHQMVWRHPFPGPGLGVRILGEVRKDYADILRQADAIYIEELYAADHYHKISQAFAVFLPVKSVGVMGDGRTYEYVVALRAVETKDFMTAGWYPLPYEDLARISSRIINEVKGINRVVYDISSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RUVC_FRACC
Sequence: MRVLGVDPGLTRCGLGVVDGGLGIRAHLVEVGVVRTPATAEVAERLCAVSDGIDAWLDRTRPEAVAVEKVFSQANMRTVMGTAQAGAVAIVLAARRGLPVGLYTPSEVKAAVTGSGRADKAQVSFMITRLLGLTEAPRPADAADALALALCHLWRGPALARFRSAAPGGPTR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: PER6_CAPAN
Sequence: GYEVIDTIK
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 6.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HDA8_ARATH
Sequence: MVTNRVDVFWHEGMLRHDAVEGVFDTGYDPGFLDVLEKHPENADRVRNMLSILRRGPIAPHVNWFTGLPAIVSELLMFHTSEYIEKLVEADKSGERCEIAAGTFMSPGSWEAALLAAGTTLSAMQHILDCHGKIAYALVRPPGHHSQPTQADGYCFLNNAALAVKLALNSGSCSRVAVIDIDVHYGNGTAEGFYTSDKVLTVSLHMNHGSWGSSHPQKGSIDELGEDVGLGYNLNVPLPNGTGDRGYEYAMNELVVPAVRRFGPDMVVLVVGQDSSAFDPNGRQSLTMNGYRRIGQIMRGVAEEHSHGRLLMVQEGGYHVTYAAYCLHAMLEGVLKIPEPHLSDPIAYYPEEEANAVAAVESIKTYHTEFVPFLRGT
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes.
What are the official names of this protein?
Histone deacetylase 8.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GUAAA_PYRAB
Sequence: MIVIMDNGGQYVHRIWRTLRYIGVESKIIPNTTPLEDIKAMNPSGIIFSGGPSLENTGNCEKILENYDEFNVPILGICLGHQLIAKFFGGKVGRGEKAEYSLVEIEILEEDEIFKGLPRKLRVWESHMDEVKELPPNFKVLARSETCPIEAMKHEELPIYGVQFHPEVAHTEHGEDILRNFAKLCGEL
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.