PharMolix/UniProtQA huggingface dataset:
Protein: TRMB_COPPD
Sequence: MLIKPQSTSSFPLNWDAIFPEKNPLAVEIGFGNGKFLKTLETTGTNVVGFEVSLLSVEKAMKVIDHTKTALLLMDGIWGLRELFSERSVDALYINFPLPWPHKKHASRRLFTLPKLQIYASRLVDNAILQLQTDVKEYAEEAIRNSEESGLFSLADYAVRNEVQVGTKYEQKWVSQGKKIYKVVLRKKRHVSVPNYLDKEVIMPHAIVHDSHGTLKAGTYRTTFGTIKLWEPFSNNQAMLLIPAIVSDDDFIGVSLQQRVYISVSPHREGFIVKLDNHADVFKTENVKSLIWLIANQISNGNIKRINVQPPSKLEYEPA
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: GSH1_DROME
Sequence: MGLLSEGSPLSWEETKALADHVREHGVNQFINLYHRLKDRQGDILKWGDEVEYIIVKFDDEQKVARVALRAQDLLAQLNEKELADPNGVKSLWRPEYGAYMIEGTPGKPFGGLMAHFNLVEANMRYRREEVTELLAKDECVMSITNFPRLGAPNFTYPLAQPRPEDPLSSARSLYFPDEAIFPGHPRFKTLTRNIRKRRGEKVSIKLKVFKDTKTKLPVEGAPPGEPDVVLLDAMGFGMGCCCLQLTFQACNITEARRLYDQLAPLCPIMLALTAASPIYRGYLTESDCRWNVISSSVDCRTEEERGLAPLDQQKFRIAKSRYDSIDSYLSPEGAKYNDVPLTYDEKVYQRLVEGGIDHLLAQHVAHLFIRDTVSLFSEKVHQNDNEDTDHFENIQSTNWQTMRFKPPPPNSSIGWRVEFRPCEAQISDFENAAIVCFVVLLTRVILSYQLNFLTPISKVDENMQTAQKRDACRKEKFWFRKSSKTTEQRAAKAQAQAQAQAKAQAQTNGKATLNGNGLANGNGNGSENSDQEEQQPLTNGSAKMNGHGSGTTNGTNGSSNGSSNGTDSDHTDTDDEENELFQLLSINEIFNGKPNVFPGLVPLIRSYLQSMEVDTDTHCTIEQYLRFIQKRAAGELITTATWMREQVLSHPDYKQDSVVSERINYDLLKRIQGIQEGKQVEPALLGQDYHSKTKTKDFIPPALQKQLAKNGCCEEK
What is the function of this protein?
Catalyzes the ATP-dependent ligation of L-glutamate and L-cysteine and participates in the first and rate-limiting step in glutathione biosynthesis.
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 3 family.
Protein: CBIN_SALHS
Sequence: MKKTLMLLAMVVALVILPFFINHGGEYGGSDGEAESQIQAIAPQYKPWFQPLYEPASGEIESLLFTLQGSLGAAVIFYILGYCKGKQRRDDRA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNAK_LISMO
Sequence: MSKIIGIDLGTTNSAVAVLEGGEAKIIPNPEGARTTPSVVGFKNGERQVGEVAKRAAITNPNTISSIKRHMGTNYKETIEGKDYSPQEISAIILQYLKSYAEDYLGETVDKAVITVPAYFNDAQRQATKDAGKIAGLEVERIINEPTAAALAYGMDKTETDQTILVFDLGGGTFDVSILELGDGVFEVHSTAGDNELGGDDFDKKIIDYLVAEFKKDNGIDLSQDKMALQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEVTLTRAKFDELTHDLVERTIAPTRQALKDANLSASDIDQVILVGGSTRIPAVQETIKKELGKEPHKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVMTTLIERNTTIPTSKSQTFSTAADNQPAVDIHVLQGERPMAKDNKTLGRFQLADIPPAPRGIPQIEVSFDIDKNGIVTVRAKDLGTGKEQNIVIKSSSGLTDEEIEKMVQDAEANAEEDKKNKENAELRNNADQLVFTVDKTLKELEGKVEEEEVKKAEAARDELQEALKGEDFDAIKEKTESLNEIVQNLSVKLYEQAAAEQQAAGGAEGQEAPQNDDVVDAEFEEVNDDDKENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RK24_HETA2
Sequence: MKKLTKTNLKYKKQSLKIGDLVEIIAGNDKKKQGTVKAIIKSQEKVIVEGINQRFKHIKPQRSNETGKINQFEAPIHRSNVKKINN
What is the function of this protein?
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L24, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CERT_CRIGR
Sequence: MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNTLSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDVCADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHNTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREESWQKRHDKEMEKRRRLEEAYKNAMAELKKKPRFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTPLPSGDAFSSVGTHRFVQKVEEMVQNHMTYSLQDVGGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWSVDVRNDWETTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSAIRKIPALTENDPETWIVCNFSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
What is the function of this protein?
Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (PubMed:19005213).
What are the official names of this protein?
Ceramide transfer protein, CERT, Collagen type IV alpha-3-binding protein.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Endoplasmic reticulum. Note=Preferentially localized to the Golgi apparatus.
Protein: ATPB_JANSC
Sequence: MANAVGKITQVIGAVVDVQFNDHLPEILNALETENDGKRLVLEVAQHLGEGTVRTIAMDSSEGLVRGQEVTDTDGPITVPVGPGTLGRILNVVGEPVDEGGPVDAEERRGIHQDAPEFADQSTEAEVLVTGIKVVDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGVSVFAGVGERTREGNDLYHEMIESGVIVPDNLPESKIALVYGQMNEPPGARMRIALSGLTLAEQFRDATGADVLFFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGTMQERITSTKRGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRAISELGIYPAVDPLDSSSRLMDPTIVGDEHYQVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVFTGSDGIQVQLEDTISSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS12_BURCJ
Sequence: MPTINQLVRKGRQSETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRKQARSKYGAKRAKAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GLGX_SHIDS
Sequence: MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGHEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLYAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALHEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: Y7585_HAEIG
Sequence: MLISHSDLNQQLKSAGIGFNATELHGFLSGLLCGGLKDQSWLPLLYQFSNDNHAYPTGLVQPVTELYEKISQTLSDVEGFTFELGLTEDENVFAQADSLSDWANQFLLGLGLAQPKLAKEKGEIGEAVDDLQDICQLGYDEDDNEEELAEALEEIIEYVRTIAMLFYSHFNEEEIESKPVLH
What are the official names of this protein?
UPF0149 protein CGSHiGG_07585.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: HSLU_ACIET
Sequence: MSSMTPQEIVSELDRHIVGQNGAKRAVAIALRNRWRRQQVDASLRHEITPKNILMIGPTGVGKTEIARRLARLADAPFIKVEATKFTEVGYVGKDVDSIVRDLVEVAVKQTREADMKKVRVRAEDAAEDRILDVLIPPARGASVDTARTGDPAGDSTARQVFRKKLREGQLDDKEIEIDLADARPQFEIMSPAGMEEMTEQLRGMFSQMGQERRRARKLKIAEAMKLLVEEEAAKLVNEEEVKTRALANAEQNGIVFIDEIDKVASRQEAGGADVSRQGVQRDLLPLVEGTTVSTKYGMVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELTSLSVQDFEAILTQTHASLVKQYQALLETEGVTLDFTPEGITRLAHIAFEVNERTENIGARRLSTVMERLLDEVSYDATRLSGQTVVVDAGYVNARLQSLSQDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFK_ACIFI
Sequence: MSQNADKIVDHFNLFKQPDYQEMFKNKQKTFENRLPADQVARGQEWTKTWEYREKNFAREALSVNPDKACQPLGRIFARGFDGTRPFVHGSQGCVAYFRSHFNRHFKEPSSCVSSSMTEDPAVFGGLNNMIDGLAISYSLYKPKMIAVSTTCMAEVIGDDLNAFIKTAKEKGNVPESFDVPFAHTPSFVGSHITGYDNMMKGILTHFWDGKAGTVPALERKPDEKINFIGGFDGYTVGNMREIKRLFSLMNVDYTILGDGSDVWDTPADGEFRMYDGGTTFAEAEAALNAKATVCMQGISTEKTMAYIQEKGQEVVALHCPIGVTGTDHFLQEVSGISGKPISEELKKERGRLVDAIGTSISYLHGKKFAIKGDPDFCLGVAGFLLELGAEPVHVVCTRGNKDWAEKMNALFASSPFGTGCHAYPGKDLWHMRSLVFTEPVDFLIGNSYTKYLERDTGTPMIHIGFPIHDRHHHHRYPIWGYQGAVNVLVWILDRIHLELDRNTLGIGTTDFSYDLVR
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein beta chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: RL16_SHEHH
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMNGVSEELAREAFTLAAAKLPLKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RS8_NEIMB
Sequence: MSMHDPISDMLTRIRNAQRANKAAVAMPSSKLKCAIAKVLKEEGYIEDFAVSSDVKSILEIQLKYYAGRPVIEQIKRVSRPGLRIYKASSEIPSVMNGLGIAIVSTSKGVMTDRKARSQGVGGELLCIVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS3_ENTFA
Sequence: MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIATKLADAAVSTIEIERAANRVNISIHTAKPGMVIGKGGSEVENLRKELNKLTGKRVHINIVEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGADIARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: Y1040_GLAP5
Sequence: MFGKGGLGGLMKQAQQMQERMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRIEIDPSLMEDDKEMAEDLVAAAFNDAVRRADEMQKEKMASVTAGMQLPPGMKFPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein HAPS_1040.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: A103_SCHMA
Sequence: MNIYLIGILCIVGLIISQGSTANGSPLDDRFNDVNTINKKQFTEEEFSRLINSMLKKYIEDKNVDIRIIGNKKDKQPTQKTTPKPTTPKQINDGTSDKTSDTHTIKRTTPKPTTPKQINDGTSDKTSDTHTIKRTTPKPTTPKQINDGTSDKTSDTHTIKRTTPKPTTPKQINDGTSDKTSDTHTIKRTTPKPTTPKQINDGTSDKPKSIADIFLINKPKVPLWIVNPLYYMVEKFVQIMGYLLEDDDTLELNLPKYYYDKSI
What are the official names of this protein?
Antigen 10-3.
Protein: RSMA_STRPN
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDILKVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLAEFAGLADALKGQGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALRL_MOUSE
Sequence: MDKKHILCFLVLLPLNMALISAESEEGVNQTDLGVTRNKIMTAQYECYQKIMQDPIQQAEGLYCNRTWDGWLCWNDVAAGTESMQYCPDYFQDFDPSEKVTKICDQDGHWFRHPDSNRTWTNYTLCNNSTHEKVKTALNLFYLTIIGHGLSIASLIISLIIFFYFKSLSCQRITLHKNLFFSFICNSIVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGVYLHTLIVVAVFAEKQHLMWYYFLGWGFPLLPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQVESNLYMKAVRATLILVPLLGIEFVLFPWRPEGKVAEEVYDYVMHILMHFQGLLVATIFCFFNGEVQAILRRNWNQYKIQFGNGFSHSDALRSASYTVSTISDMQGYSHDCPTEHLNGKSIQDIENVALKSENMYDLVM
What is the function of this protein?
Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
What are the official names of this protein?
Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLT35_DROME
Sequence: MMQIKRLLCKSCGLGTLLVAVVWLLALLFYSHSLRSSIRSAGWRIDEGNATPRAELSYQARVTVGCTPNASITTGESPAAPKPPSDPEQLELLGVVRNKQDKYIRDIGYKHHAFNALVSNNIGLFRAIPDTRHKVCDRQETTEAENLPQASIVMCFYNEHKMTLMRSIKTVLERTPSYLLREIILVDDHSDLPELEFHLHGDLRARLKYDNLRYIKNEQREGLIRSRVIGAREAVGDVLVFLDSHIEVNQQWLEPLLRLIKSENATLAVPVIDLINADTFEYTPSPLVRGGFNWGLHFRWENLPEGTLKVPEDFRGPFRSPTMAGGLFAVNRKYFQHLGEYDMAMDIWGGENIEISFRAWQCGGAIKIVPCSRVGHIFRKRRPYTSPDGANTMLKNSLRLAHVWMDQYKDYYLKHEKVPKTYDYGDISDRLKLRERLQCRDFAWYLKNVYPELHVPGEESKKSAAAPIFQPWHSRKRNYVDTFQLRLTGTELCAAVVAPKVKGFWKKGSSLQLQTCRRTPNQLWYETEKAEIVLDKLLCLEASGDAQVTVNKCHEMLGDQQWRHTRNANSPVYNMAKGTCLRAAAPTTGALISLDLCSKSNGAGGSWDIVQLKKPTEAEGRAKEARNSDKAL
What is the function of this protein?
Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:11925450, PubMed:12829714).  Displays the same enzyme activity toward MUC1, MUC4, and EA2 (PubMed:11925450, PubMed:12829714).  Not involved in glycosylation of erythropoietin (EPO) (PubMed:11925450).  It can both act as a peptide transferase that transfers GalNAc onto unmodified peptide substrates, and as a glycopeptide transferase that requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties (PubMed:11925450, PubMed:12829714).  Protein modification by this enzyme might be important for cytokinesis and tube formation during embryogenesis (PubMed:16251381, PubMed:20807760).  Together with Pgant3, regulates integrin levels and activity-dependent integrin signaling at the synapse in neurons and muscles (PubMed:25253852).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 35A, Protein l(2)35Aa, Protein-UDP acetylgalactosaminyltransferase 35A, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 35A, pp-GaNTase 35A, dGalNAc-T1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: DEFM0_ARTOT
Sequence: MQFTKLATILLVSLMGSAAIAAPATNNAAVDAAADATPAVEKRGFGCPFNENECHAHCLSIGRKFGFCAGPLRATCTCGKQ
What is the function of this protein?
Antibacterial peptide with potent activity against both Gram-positive and Gram-negative bacteria (PubMed:22586077).  May kill bacteria via an intracellular action mode to affect protein folding (PubMed:22586077).  Does not show effects on tested filamentous fungi or on the yeast S. cerevisiae (PubMed:22586077).  Does not act by destroying the membrane integrity, which is consistent with its nonamphiphilic architecture (PubMed:22586077).  Acts more rapidly than vancomycin, suggesting it does not act by inhibiting cell-wall biosynthesis (PubMed:22586077).  Does not cause hemolysis and has no cytotoxic effect on HEK cells (PubMed:22586077, PubMed:27084888).  In vivo, is as efficient as vancomycin to protect mouse peritonitis models from S. aureus and P. aeruginosa infections (PubMed:22586077).
What are the official names of this protein?
Fungal defensin micasin, Fungal defensin-like peptide, DLP, fDLP.
What is the protein family that this protein belongs to?
Belongs to the invertebrate defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VP4_AHSV4
Sequence: MEPYAILYVTQEIEYLLKDSFLPKWELDGIKDLNTLWLERGRMACDTYAIGKIEQWSVRQLRAHRFLFISTKRKIRLKDCTISPDIFILKKELKEYDMKRFETLIGRRRVTLRKSFGNMLRAYAFQHVTVLHGSEAETLSYADPKRHVVKGQPKAAPMYDHPDRWWRDVDDGPTDKKLVSMLDYIIYSADEVYYVGCGDLKTLEQFASRDRKRFDRIKWICIDPIAPETSYANVKVVREKVVSARDLKHYLMRDEVERLLIWDVSADGLKGTIEWEKQRFKEDRNGENIAEALCADFALALIKHRIPEESDEYICRSSWLIPQPGAPITMYELRNLMRLDGYSHVERKHIPRAYARKIDAEVARRLVEEYHGEDVGRLLKRSLYEDIHIERADGLTDGDERTRADLFYLTNMRNVAFMHDVYRVVEKSFISTLWVSNRQNFTYDDVPVNRNFITLRFSKKNRRVLDGNGAILFLMWQHPKDFPKTMNYDPSWAENYAVIFYHALTSPVPDLSLCRFIGLRLMSSTLRINSDRAHQVTDILKKLGLDVSGHLFICLMSNSYVADLDWWFRMILEWSVKDREGKLAALSEAKAELIEWRDEKADEPWHIKNDLLAALFEFIYFAKHFDINERYVESWIQYLRNA
What is the function of this protein?
The VP4 protein is one of the five proteins (with VP1, VP3, VP6 and VP7) which form the inner capsid of the virus.
What are the official names of this protein?
Core protein VP4, Inner capsid protein VP4.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP4 family.
What are the subcellular locations of this protein?
Virion.
Protein: ALR_RICRO
Sequence: MSLCTVEINLSTIKNNYLLLQDVCKTSLVGAAVKANGYGLGAIQISKALIEENCRHFFVASSEEGVNLRNALGLDINILVLNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKNRLLPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIISHLAISEEIDNPYNLEQLNRFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPLTKNPVTLKAPIIHLQNLTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEIFLGQEAEIIGNYCTPNKIASIIGTIGYEVLTNLGSRYKRKYIG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: DNBI_VZVD
Sequence: MENTQKTVTVPTGPLGYVYACRVEDLDLEEISFLAARSTDSDLALLPLMRNLTVEKTFTSSLAVVSGARTTGLAGAGITLKLTTSHFYPSVFVFHGGKHVLPSSAAPNLTRACNAARERFGFSRCQGPPVDGAVETTGAEICTRLGLEPENTILYLVVTALFKEAVFMCNVFLHYGGLDIVHINHGDVIRIPLFPVQLFMPDVNRLVPDPFNTHHRSIGEGFVYPTPFYNTGLCHLIHDCVIAPMAVALRVRNVTAVARGAAHLAFDENHEGAVLPPDITYTYFQSSSSGTTTARGARRNDVNSTSKPSPSGGFERRLASIMAADTALHAEVIFNTGIYEETPTDIKEWPMFIGMEGTLPRLNALGSYTARVAGVIGAMVFSPNSALYLTEVEDSGMTEAKDGGPGPSFNRFYQFAGPHLAANPQTDRDGHVLSSQSTGSSNTEFSVDYLALICGFGAPLLARLLFYLERCDAGAFTGGHGDALKYVTGTFDSEIPCSLCEKHTRPVCAHTTVHRLRQRMPRFGQATRQPIGVFGTMNSQYSDCDPLGNYAPYLILRKPGDQTEAAKATMQDTYRATLERLFIDLEQERLLDRGAPCSSEGLSSVIVDHPTFRRILDTLRARIEQTTTQFMKVLVETRDYKIREGLSEATHSMALTFDPYSGAFCPITNFLVKRTHLAVVQDLALSQCHCVFYGQQVEGRNFRNQFQPVLRRRFVDLFNGGFISTRSITVTLSEGPVSAPNPTLGQDAPAGRTFDGDLARVSVEVIRDIRVKNRVVFSGNCTNLSEAARARLVGLASAYQRQEKRVDMLHGALGFLLKQFHGLLFPRGMPPNSKSPNPQWFWTLLQRNQMPADKLTHEEITTIAAVKRFTEEYAAINFINLPPTCIGELAQFYMANLILKYCDHSQYLINTLTSIITGARRPRDPSSVLHWIRKDVTSAADIETQAKALLEKTENLPELWTTAFTSTHLVRAAMNQRPMVVLGISISKYHGAAGNNRVFQAGNWSGLNGGKNVCPLFTFDRTRRFIIACPRGGFICPVTGPSSGNRETTLSDQVRGIIVSGGAMVQLAIYATVVRAVGARAQHMAFDDWLSLTDDEFLARDLEELHDQIIQTLETPWTVEGALEAVKILDEKTTAGDGETPTNLAFNFDSCEPSHDTTSNVLNISGSNISGSTVPGLKRPPEDDELFDLSGIPIKHGNITMEMI
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).