PharMolix/UniProtQA huggingface dataset:
Protein: NDUBA_HUMAN
Sequence: MPDSWDKDVYPEPPRRTPVQPNPIVYMMKAFDLIVDRPVTLVREFIERQHAKNRYYYYHRQYRRVPDITECKEEDIMCMYEAEMQWKRDYKVDQEIINIMQDRLKACQQREGQNYQQNCIKEVEQFTQVAKAYQDRYQDLGAYSSARKCLAKQRQRMLQERKAAKEAAAATS
What is the function of this protein?
Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I.  Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10, Complex I-PDSW, CI-PDSW, NADH-ubiquinone oxidoreductase PDSW subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB10 subunit family.
Protein: THII_SULTO
Sequence: MIIIVRLAGEIGIKSPRSRKNFEHALINNIKNVIDVEEVSIDQGYIILNTKGDFSKLSKVFGIASFSPADVISFSKLQDIVDFVKNKYAEKVKGKKFAIRVRRVGKHNFTSLDAAKVIGSSLYPYSSGVDLENPEIEIHVDIRQDYAYVYDKVYEGARGLPIGTTGRTIVLFSGGFDSPIATWMMMKRGSSVTLLNFKLGGEVHKKIVLDEVKILSEWNSGHKIKVYFVNGIKVLSALAGVKRYIRVVVLKRIMYKTAELLAKKINAYSVTTGESLSQVSSQTMKNLFVTEYDINIPIFRPLIGFDKEEIIELSRKVGTYEYSSKLPEYCAISSKSTTSANLEEVLESEKQVNIEYEKLIDEAEVVEV
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS (By similarity).
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPGH_CAUVC
Sequence: MSDRSSLFDVRSSTSVTLDQVVRRDTVEIPDEAALAMPVQPLSFWQGGARRATALTQDMNLRRWMLGLMTIAMGVAGWKASFDTIALGGVTRLEAVVLTLLAPLFLALSLWFCTALIGFVVLMGRPKDPLGIDSEAPMPKLHTRTAILMPVYNEDAAAVFARLRAMDASIAETGSARNFDIFVISDTRDAQVALAEQACFARFRREANCNVYYRIRKENTGRKAGNVADWVSRWGSAYEHMLVLDADSLMTGEAMVRLADAMERHPGAGLIQTMPMIINGQTIFARTLQFATRLYGRVAWTGLAWWSGSESSFWGHNAIVRTRAFAETCGLPHLPGPKPFGGEVMSHDALESALLRRGGWSVHLAPYLDGSYEESPSNLLDFATRDRRWCRGNIQHVPLIALPGLHWMSRMHLVIGVLSYALSPLWFFCLSAGLISRALMPELKKAAFTMADLKAAAHALIDWSEIQATAWAMIITFVLLFGPKILGAILVLARKGEVKGFGGKRRMAAGLGVEMLLSALVAPMLMFTQTRAIVEILAGKVGGWAAQRRDADKVDFKEAWAAMGWISLSGLILAASFWFTPDLLTATAPILAGLVLAVPLTMLGAHKVAGLKLKANGLFMTPEERRPPAIVRAAVGAACEPPIRWFARNGRPIGPTTKIRDAA
What is the function of this protein?
Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis glucosyltransferase H.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. OpgH subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPF2_BRADU
Sequence: MAESHGGAKGPAAGAHTGAEGGHGGGFPPFESSTYASQLVSLAIFFVVLYVIVSKLALPKVGGAIEARQNKIEGDLAEAQTLRDQSDAALKAYESELASARSRAQAIGNESRDKANAQAETERKALEEQLAAKLAGAEKTIASTRTAAMSNVRGIAADAAGQIVQQLTGVVPDAASVNAAVDASLKG
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AZLD_BACSU
Sequence: MTMTMTQQMITIAMVVLGTMLTRFLPFMIFPSGKPTPKYVQYLGKVLPSAVIGLLVIYCLKDVSLLSGSHGIPELVGAAAVVLLHLWKKNMLLSIAGGTVVYMVLVQLVF
What is the function of this protein?
Involved in branched-chain amino acid transport.
What are the official names of this protein?
Branched-chain amino acid transport protein AzlD.
What is the protein family that this protein belongs to?
Belongs to the AzlD/HI_1737/HP1330 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS16B_ARATH
Sequence: MVVRIRLSRFGCKNRPFFRVMAADSRSPRDGKHLEVLGYFNPLPGQDGGKRMGLKFDRIKYWLSVGAQPSDPVQRLLFRSGLLPPPPMVAMGRKGGARDTRPVDPMTGRYVDAENKTVNANDNQPKEEDTEAKSA
What are the official names of this protein?
30S ribosomal protein S16-2, chloroplastic/mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Mitochondrion. Plastid, chloroplast.
Protein: ITPA_EMENI
Sequence: MKTINFITGNKNKLAEVRAIIGNVVDVQNQTVDVPEIQGTIEEIAKEKCRHAANAVGGPVLTEDTALGFHALKGLPGPYIKFFLEALGHEGLNKMLDGFESRGAEAVCTFAFSPGPGSEPILFQGRTEGVIVSPRGPANFGWDPIFEYEGQTYAEMTKEEKNKISHRYKALVKLQQWLVDELS
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FAR10_MANKU
Sequence: PAASESGFRRDP
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-10, FMRFa-10.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_ECO8A
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: LIS12_PARTE
Sequence: MVLTARQRDELNQAIHQYLLISYQQSAQVFKTEAVVKDGQIEADLLEKKWNSIVRLSKRVITLEQQVEQLNEQLAQAQAGKIQFNKSDDEQRLTPFEKFKLEGHRAGVNCVAFHPQYQILGSASDDGSIKLWDYESGHFEKTLKGHTSNVNCLAFDPTGKYICSASSDLSIKLWELKNHTCVKTLIGHEHSVSTVQFSDHGDFILSASRDKSIKLWEVQTGFCKKTFSEHQEWVRCAVFSNDEKQMASCSQDQMIYIWVIDSGQILHQLSGHEHVVEQVKYVPEHGAKQILTQQQQQNIQTINLLVSVSRDKEIKIWNTILGTNLFTLSGHDNWVNGVSFHPDGVHMLSVSDDKTIRVWNLKEQKQKKKIENAHDKFILKCEINKFIFATCSVDQTIKLWLLS
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end.  Required for several dynein- and microtubule-dependent processes.
What are the official names of this protein?
Lissencephaly-1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to the plus end of microtubules and to the centrosome.
Protein: GATA_COXB1
Sequence: MHQKTIAELKQDLRDKTISSVELTQHFLDRIKTINPTLNSFISITEEYALTQAKAADARLAKGEATSLTGIPIAQKDIFCTKDIKTSCGSKMLDNFIAPYDATVVEQLNKAGAILIGKTNMDEFAMGSSNENSYFGAVKNPWDLERVPGGSSGGSAAAVAARLVPGATGTDTGGSIRQPAALCGITGLKPTYGRVSRYGMIAFASSLDQAGPMAQTAEDAALLLNALAGHDAKDSTSINKNVPDYTATLTTSLEGLKVGLPKEYFGEGLNSSIAESIETVKKTLEKMGATFIEIQLPHTDFAAPAYYVLAPAECSSNLARYDGVRYGYRCDKPVDLDDLYKRSRTEGFGSEVKRRIMIGTYVLSAGYYDAYYLKAQKIRRLIRDDFMKAFETVDVILTPATPTPAFKLNEKIADPVAMYLSDVYTIAVNLAGLPAIAFPAGFMDQLPIGAQLIGNYFEEARLLNITHRYQQETDWHKQSPKLR
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: AROC_BURM7
Sequence: MSGNTLGTLFTVTTFGESHGPAIGCVIDGCPPGMALTEADVQLELDRRKPGTSRHVTQRQEPDQVEILSGVFEGVTTGAPIALLIRNTDQRSKDYGNIAETFRPGHADYTYWQKYGVRDYRGGGRSSARLTAPVVGAGAIAKKWLRERFGVEVRGYMSALGEIEIPFVDWSHVRENPFFAPNADIVPQLEDYMDALRKDGDSIGARIDVVASGVPVGWGEPLFDRLDADIAHAMMGINAVKGVEIGAGFASVAQRGSVHGDELTPDGFVGNHAGGVLGGISTGQDITVSIAIKPTSSIRTPRRSITRAGEPAVVETFGRHDPCVGIRATPIAESMLALVLIDHALRHRAQCGDVSSATPRIAARAPDAQ
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RUVA_SHEDO
Sequence: MIGRLNGILVEKHAPEIVLDVGGVGYELQVPMTSFYELPELEQSATLYTHFVVREDAQLLYGFITKQERALFRLLIKTNGVGPKLALTILSGMTAGEFVSCVERDDIVTLVKLPGVGKKTAERLVVEMRDKLKSLLEASVGNEREFMLQTNYTAPAANAEEDAISALVSLGYKPPQASRAVSKAYKEGMDTETLIKLALKSML
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: SYNC_ENTBH
Sequence: MKLQDNLKSIKKELERIKVENWSKENIDKNTYRYIRLFDIDDSLMNQKICFFGWVKSSRSSSKISFIELISQFKIIKCVIPTKVKLTDHTTLKVWGIMKPNNGNDEHQFEIDVQAYEVYGGYQAPSFPLNIHSDKDTLLDLAHLGLRMPHRILFLQAQNELLKALRKFYWNNNYTEITPPTLVQTQVEGGATLFKLNYYDQPAYLTQSSQLYLETVAPVVGKAFCIMPSYRAEKSKTSRHLSEFTHVEAELVDIQFDELMDQIEQLIRSTINEFYKNILPEIKKIDNDFQPVVLSDKQFKKITYEDAIHFLIAQNHKKTDNTDYQLGDDISDASEKFLLETYGENQPIFLIRFPTDHKPFYVAKDQYGTQTCDLLFPGIGEIVGGSMRETNYNNLLDGFKRENIDHEPYSWYLDMAKFGPSPHGGYGLGFERLLMCLMKYKSVDQSTLYCRKPSRCTP
What are the official names of this protein?
Probable asparagine--tRNA ligase, cytoplasmic, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_HAEDU
Sequence: MAFNLKNRHLLSLVNHTEREIKYLLALARDLKRAKYSGTEQQTLKGKNIALIFEKTSTRTRCAFEVAAYDQGAQVTYIDPNSSQIGHKESMKDTARVLGRMYDAIQYRGFKQATVNELAKYAGVPVFNGLTDEFHPTQMLADVLTMLENCEKPLNQISYVYMGDARNNMGNSLLLIGAKLGMDVRICAPQALLPEDSLVTLCQQFAQQSNARITITDDIDLAIQGVDFIHTDVWVSMGEPLETWGERINMLMPYQVTPALMQRTGNPNVKFMHCLPAFHNSETTMGKQIAEQYPQLANGIEVIEEVFESSANIAFEQAENRMHTIKAVMVASLA
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y064_SYNY3
Sequence: MPDTSAFSATTRPYFATVARGLEAIAAQELTELGAEQVKPEFAGVAFIGDRALLYRINLWSRLIYRVLMPMATVKAFNAQDLYRSIKKIDWDEYFSPEQTLQINCTGKNPQLNHSHFTALQVKNAIVDQQRDRYQRRSSVDLEQPDIVINAHIHQNHCQLSLDSTGFSLHRRGYRPALGNAPLKETLASALLTMAGWTPELPLYDPLCGSGTFLLEAGLQSLNIAPGKFQPGFCFQQWPDFDQDLWHSLLQTAKAGERDTLQAPLWGSDGDREVIQAAKSNAQQCQLGGKIHWQKLNFADIEPPAAEGVLICNPPYGKRIGQEEALGDFYQQIGDVLKQRFRGWTAFVFSGNKALTKRIGLRTSARFPVNNGGLPCTLLKYELY
What are the official names of this protein?
Putative RNA methyltransferase slr0064.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: KUP_BIFAA
Sequence: MAIVALGVVYGDIGTSPLYTMQTFLNGQGGLAHTDRAAVLGILSLVFWSITLITTVKYVFIAMRIDNNGEGGIFALYSLIRKYGAWLAIPAMLGGAAFLADSVLTPAVSISSAVEGLETLPLLEPIMSGNKELTLMITIVIIVCLFAVQSRGTERIGRTFGTVVMIWFSFLAVVGLVNLSSDWSVLEALNPVYGVEFLFSHHNAAGLAVMGTVFLSTTGAEALYSDMGHVGRGNIYFTWPFIKIALVFCYFGQGAWMLNHWDDTAYNHMHGLNPFFEMMTPSVRYVAVLLSVCAGVIASQALITGAYTMVSEATRLNWMPHLQVRYPARTRGQLYIPVVNAVLCVSTLLVLAMFRDSEHISAAYGLALTVTMITTTILLAVYIWHDGKRVGAVVFTVVFLAIQFLFFFASMAKFLHGGWFTMLLTLAILLIMYTWNEGTKLERAQRRHMQPADCVPVLKRLHEDDSIPYFADNIVYLTSDPEMKRVDTDIFFSIFADHPKRARAWWAVSVETSDNPFTREYSVENFGTDFLFRVRIRLGFKVSQSIPAYIHQIMNDLSKSGDLPKQTTRYPKLDADPNIGPIRYVLIHKALMPESKVSQKGAISLQIKYAIRHLAGSPVKWFGLAPYNPLIEIQPLFLATERPPRLKRV
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEF11_NPVBM
Sequence: MPPKNCTHLGGCNSDCLTRSEIQALFREAINTLKHTMNTEDVCAHMLDIVSFERIKEYIRANLGHFTVITDKCSKRKVCLHHKRIARLLGIKKIYHQEYKRVVSKVYKNQTW
What is the function of this protein?
Involved in late/very late gene activation.
What are the official names of this protein?
Late expression factor 11.
What is the protein family that this protein belongs to?
Belongs to the baculoviridae LEF-11 family.
Protein: FIXX_RHILT
Sequence: MKAIVKRRVEDKLYQNRYLVDPGRPHISVRKHLFPTPNLIALTQVCPAKCYQLNDRRQVIIVSDGCLECGTCNVLCGPDGDIEWTYPRGGFGVLFKFG
What is the function of this protein?
Could be a 3Fe-4S cluster-containing protein.
What are the official names of this protein?
Ferredoxin-like protein.
What is the protein family that this protein belongs to?
To ferredoxins from P.putida and C.tartarivorum, ferredoxin I from A.vinelandii, ferredoxin II from D.desulfuricans.
Protein: PYRD_ACAM1
Sequence: MDLYQQGLQPLLFSALKADPETVHRQLMRTCAWLDRNVDQGLAQGLQRRLASSLQVEDPRLSQSLWGLSFANPIGLAAGFDKDGVATNIWPRFGFGFAEVGTVTFHAQPGNPQPRLFRLPEDQAALNRMGFNNQGAAAMAKVIAASLDRQARSYPLGINLGKSKVTPLEQAVADYVGSFQLLKTYGDYFVVNVSSPNTPGLRSLQAVEQLAPILAGLQAENTEGKPLLVKIAPDLEWKDIAAIVDLAQVHQLAGIIATNTTIRRDLKTERIAATGNVPSEEAGGISGAPVRSRSTDVIRFIHKQTQGQLPIIGVGGIFTAEDAWEKLCAGASLLQVYTGWVYEGPWMVRRILEGLLVKMQEEGIQQLSEIVGQK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEUC_THEKO
Sequence: MTLVEELLGAKTGEVVVREVDLVYAHDGTMPLIIEAFRRNFTRVVPRTYVFFDHVFPAPTVKIANLQKEILEFAGEQGIPVIQGQGISHQLAVEMGLADNARIVVGADSHTPTLGALGVFAVGIGATDTAVVMGLGKTWFRVPESVSVVFEGRPGKNVMAADAMIHIITALRDFEMNYKAIEFFNVPFSFDERLTLTNFSVEANAKTGIIGEEYSGDGYVLELGIDLSSLPPMVAKPHHPSNGVPVEEVEGTKIDQVFIGSCTNGRFEQIERAAEILAGEEVAVRTIIGPASANVYRRMIETGIAKVLIDAGAVILPPGCGPCLGRHMGVAGDGDVILSTTNRNFRGRMGSPNSEIYLASPVTAALSALYGEITTPEGGA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: RL1_HAEIN
Sequence: MAKLTKKMKAIKAGVDSTKAYEINEAIAVLKQFATAKFVESVDVAVNLGIDPRKSDQNVRGATVLPHGTGREVRVAVFTQGANADAAKEAGADLVGMEDLAEQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKSGQIRYRNDKNGIIHTTIGKANFSEVQLKENLQALLAALNKAKPTTAKGIFIKKVSISTTMGAGVAVDQASL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: LFTR_LAWIP
Sequence: MLSALSNDPMYFPPLETAFDNGLLAYGGDLSPQRLLSAYTKGIFPWYDNNSPILWWSPDPRCILLPENFRIPKTIQRELKKCTFSVTINNAFTEVITACATLPRTKQKGTWITQDMKMAYIQLHKLGFSHSIEVWDNSTLVGGLYGVALGKAFFGESMFHIAPHASKLALVWLAQYLWSYNFDFIDCQMPTTHIMRYGATLISRNEFLTRLTIAVTTGTSQASTKEAL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPRI_MYCTU
Sequence: MRWIGVLVTALVLSACAANPPANTTSPTAGQSLDCTKPATIVQQLVCHDRQLTSLDHRLSTAYQQALAHRRSAALEAAQSSWTMLRDACAQDTDPRTCVQEAYQTRLVQLAIADPATATPPVLTYRCPTQDGPLTAQFYNQFDPKTAVLNWKGDQVIVFVELSGSGARYGRQGIEYWEHQGEVRLDFHGATFVCRTS
What is the function of this protein?
Strongly binds and inhibits lysozyme, may help bacteria survive in lysozyme-producing host cells.  When overexpressed in M. tuberculosis or M. smegmatis increases resistance to hen egg white lysozyme.  M. smegmatis overexpressing LprI survive better during intracellular infection of peritoneal and monocyte-derived macrophages, both of which produce lysozyme during infection; M. smegmatis does not encode this protein.  Somewhat better survival is seen in human cell lines when M. smegmatis cells express both proteins from this operon, i. e.  GlbN (HbN) and LprI.
What are the official names of this protein?
Lipoprotein LprI, Glycolipoprotein LprI, Lysozyme inhibitor LprI.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MliC family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted, cell wall. Cell surface. Note=Protein is accessible to externally added trypsin and alpha-D-mannosidase.
Protein: CAS2A_FRATN
Sequence: MQLRKEYLIAYDIEDNKTRTIIYKQLLAYGLKAVQKSVFWGYVSIAELNAIKRLFDSSLTISDKVFITRVNMHEQKLDYSFGYDDKTFKDWDEYGHI
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Functions as a ssRNA-specific endoribonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endoribonuclease Cas2 1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
Protein: BET_SFVCP
Sequence: MDSYQEEEPVASTSGLQDLQTLSELVGPENAGEGDLVIAEEPEENPRRPRRYTKRDVKCVSYHAYKELEDKHPHHIKLQDWIPKPEEMVAQKVQNQDVGTILSFDVTCLKSITSLGRNDPGNDPSIMSHVLPVVTPWPMSQDHYAPTLFGLLDRYYKGYLENPATFQTWKFTCQEDPSGKRYMGTQFWVPPLGQVNIQFYKNYQIVTCCQALDPFANIFHGTEEEMYDIDSGPDVWCTPSLCFKVIYEGAIGQKQEQKSWLCRLGYGHRMGANDYRRVDLYAMKQGKKNPYGDKGDAALQYAYQVKRGCKAGCLASPVLNFKALQFHRTLMADLTNPKIGQGYLAHGYHAAMEAYGPQRGSSEERVWWNATRNQGKKDEYYREGGEEPHYPNTPAPHKKTWEERHKVLKLSPFATPSDIQRWTTRALPYGWKVIDGNGDDYTSRRNIRTLTEMTQEEIRKRWERGYCDPFIDSGSDSDGPLSKPQTVKVW
What is the function of this protein?
Bet counteracts the innate antiretroviral activity of APOBEC3 family defense factors by inhibiting their incorporation into virions.  May be implicated in the establishment and/or maintenance of viral persistance.  Bet is required for viral replication (By similarity).
What are the official names of this protein?
Protein Bet.
What are the subcellular locations of this protein?
[Isoform Bet]: Host cytoplasm. Host nucleus. Secreted. Note=Bet is highly expressed in infected cells, where it localizes to both cytoplasm and nucleus. Also secreted and internalized by non-infected surrounding cells. SUBCELLULAR LOCATION: [Isoform Bel-2]: Host nucleus.
Protein: RL31B_XANAC
Sequence: MKDNVHPNYKDVVFHDVTSDFKILTRSTMTSKETVKWEDGQEYPLIKVEISSSSHPFYTGKHKVIDTGGRIDKFQKRYAR
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: Y1611_BURO1
Sequence: MIIVLSPAKSLDYETPAHVESYTKPAFVDDASELIDGLRKLSPQDIATLMDISDPLARLNFQRYADWSPTFTPANAKQAVLAFNGDVYEGFDAKSLSSTDLDYAQQHVRVLSGLYGLLRPLDLLQPYRLEMGTRFANARGKDLYAFWGDRITRALNEQLETRSGAARVLVNCASTEYFKSVKPKLLAAPVITPVFEDWKGGRYKIISFHAKRARGLMARFVVENRITDPNALKEFATEGYAFDAAASNDSTYVYRRRVGE
What are the official names of this protein?
UPF0246 protein Bcen_1611.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: Y1071_STAAR
Sequence: MEYEYPIDLDWSNEEMILVINFFNHVEKYYESGVTAGDFMDAYKRFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK
What are the official names of this protein?
UPF0223 protein SAR1071.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: TRML_BURCM
Sequence: MFNVILVAPEIPPNTGNVIRLCANTGARLHLIEPLGFPLDDAKMRRAGLDYHEYAEMRVHRDWDAFVAAEAPDPARMFAFTTRGSGRFHDHAFVPGDWFVFGSETRGLPADVLERFPNEQRVRLPMRPGNRSLNLSNTVAVVVFEAWRQAGFEGGA
What is the function of this protein?
Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA).  Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
What are the official names of this protein?
tRNA (cytidine(34)-2'-O)-methyltransferase, tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.