PharMolix/UniProtQA huggingface dataset:
Protein: ESXA_STAA8
Sequence: MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEIAANWEGQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ
What is the function of this protein?
Virulence factor that is important for the establishment of infection in the host.  EsxA is required for EsxB synthesis as well as secretion (By similarity).  Modulates host cell apoptotic pathways and mediates together with EsxB the release of S. aureus from the host cell.  By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity (By similarity).
What are the official names of this protein?
Type VII secretion system extracellular protein A, Ess extracellular protein A.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. sagExaA-like subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: CYSN_FRAT1
Sequence: MSHKSDLIATNIQKYLQQHQQKELLRFITCGSVDDGKSTLIGRLLHDSKLIFEDQLASIVADSKKVGTQGDRLDLALLVDGLQSEREQGITIDVAYRYFSTDKRKFIIADTPGHEQYTRNMATGASNCDLAIILIDARKGLQTQTRRHNFICSLLGIKHVIVAVNKMDTVGYSQQIYKSIQDEYLKLAGSLQIPDIRFVPISALDGDNVVSKSPKMPWFRGSPLMHYLETIKIDYAYTDEFRFPVQLVCRPNSEFRGFQGTVVSGSAKIGDTIRVMPSGKITTIKSILSFDGKLNEAEAGQSITITTYDEIDISRGDMIVHKDAISHVSSMLRANIVWMSEQPLIEYKDYYIKFLTKQVIGSVNKFNYKTDINTLKEVACGTLELNEIATIELKLSEPVCFDSYQKNRTIGAFIIIDRLTNVTAGAGMVIKPLAANDKKDSTNDYSEFELELNALIRKHFPHWDAKNLRE
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: YCF3_OENEH
Sequence: MPRSRINGNFIDKTFSIVANILLRIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEIDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAEAWFDQAAEYWKQAIALTPGNYIEAQNWLKITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: IBP3_BOVIN
Sequence: MLRARPALWAAALTALTLLRGPPAARAGAGTMGAGPVVRCEPCDARAVAQCAPPPPSPPCAELVREPGCGCCLTCALREGQPCGVYTERCGSGLRCQPPPGDPRPLQALLDGRGLCANASAVGRLRPYLLPSASGNGSESEEDHSMGSTENQAGPSTHRVPVSKFHPIHTKMDVIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNMLSPRGIHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPGFDVKGKGDVHCYSMESK
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.  Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.  Promotes testicular germ cell apoptosis.
What are the official names of this protein?
Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3.
What are the subcellular locations of this protein?
Secreted.
Protein: UB12A_XENLA
Sequence: MEILMTVSRIASICTMGANASALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQPRKKENLLTCLSDLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNGRIPNGNIDNENNNSAPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSDISKNSESGYILFYQSRD
What is the function of this protein?
Deubiquitinating enzyme.  Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 12-A, Deubiquitinating enzyme 12-A, Ubiquitin thioesterase 12-A, Ubiquitin-specific-processing protease 12-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP12/USP46 subfamily.
Protein: SYA_STRCO
Sequence: MESAEIRRRWLSFFEERGHTVVPSASLIADDPTLLLVPAGMVPFKPYFLGEVKPPFDRATSVQKCVRTPDIEEVGKTTRHGTFFQMCGNFSFGDYFKEGAITYAWELLTSAQDKGGYGLDPERLWITVYQDDDEAERIWHDVVGVPSERIQRLGKKDNYWSMGVPGPCGPCSEINYDRGPEFGVEGGPAVNDERYVEIWNLVFMQYERGEGIGKEEFEILGELPSKNIDTGLGLERLAMILQGVQNMYEIDTSMAVINKATELTGVAYGDAQASDVSLRVVTDHMRTSVMLIGDGVTPGNEGRGYVLRRIMRRAIRNMRLLGATGPVVKDLIDVVIGMMGQQYPELVTDRERIEKVALAEENAFLKTLKAGTNILDTAVSDTKASGGTVLAGDKAFLLHDTWGFPIDLTLEMAAEQGLSVDEDGFRRLMKEQRERAKADAQAKKTGHAGAGAYREIADKAGATDFVGYTDTESESTIVGILVDGASSPAATEGDEVEIVLDRTPFYAEGGGQIGDTGRIRVDTGAVIEVRDCQKPVPGVYVHKGVVQVGEVTVGAKAQASIDDRRRKAIARAHSATHLTHQALRDALGPTAAQAGSENQPGRFRFDFGSPSAVPTAVMTDVEQKINEVLARDLDVRADVMGIDEAKKQGAIAEFGEKYGERVRVVTIGDFSKELCGGTHVHNTAQLGLVKLLGESSIGSGVRRIEALVGVDAYSFLAREHTVVAQLQELIKGRPEELPEKVSAMLGKLKDAEKEIEKFRAEKVLQAAGGLADSAKDVRGVALVTGQVPDGTTADDLRKLVLDVRGRIQGGRAAVVALFTTVNGKPLTVIATNEAARERGLKAGDLVRTAAKTLGGGGGGKPDVAQGGGQNAAAIGDAVDAVERLVADTAK
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1352_SULIY
Sequence: MSMPYDNEAKIKQAVILLQKIVNDTSVPRNIRRAATDAIRNLQDLGLSPAVRAANAIGILEDISQDPNMPTHARISIWNVVSILETVKD
What are the official names of this protein?
UPF0147 protein YG5714_1352.
What is the protein family that this protein belongs to?
Belongs to the UPF0147 family.
Protein: ATPL_BACC7
Sequence: MSLGVIAAAIAIGLSALGAGIGNGLIVSRTIEGVARQPELKGALQTIMFIGVALVEALPIIGVVIAFIVMNK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBM_SACOF
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTASQND
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CYT2_CROAD
Sequence: MALLRGFLVCSLLLLSCICKEALGTRLLGGLENASPEEPGVARALQFAMNEYNRGSNDMYSSRVSEVVEAQKQIVSGIKYYFTVKIGRTVCRKGATDLENCAFHNAPKLAQTMTCTFEVYNIPWRNFISLEKSSCT
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin-2.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARLY_METSB
Sequence: MSNKMWGGRFASGPDAIMEEINASIGFDYRLAMQDIAGSKAHVAMLADVGIVSADDAADITQGLEAIKAEIESGAFTFSRALEDIHMNVESRLAALIGPAAGRLHTARSRNDQVALDFRLWVRDTIDALDGQLRGLQLALAEKAKLYAGAVMPGFTHMQSAQPVTFGHHLLAYVEMFARDRSRLRDARARLNESPLGAAALAGTSFPIDRHATARALGFDRPTANSLDSVSDRDFVLETLSAAAIAAVHLSRFAEEIVLWSTPQFGFARLSDKFSTGSSIMPQKRNPDAAELVRGKAGRVIGALTGLLVVMKGLPLTYSKDMQEDKEGAFDALHSLSLCLAAMTGMVKDIEPDTERMKAAAGAGYATATDLADWLVKALGLPFREAHHVTGRLVAAASAQDKGLEELALAEMQAVEPRINAGVFAVLGVENSVRSRMSYGGTAPANVSEQAERWLGALAAEPASKI
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_ERYLH
Sequence: MPKRILIGTVTSDKTDKTVTVLVERKVKHPLYGKIIRRSKKYHAHDEKNEYTLGDVVRIEETKPISKTKTWAVKDRVVAGGTQAIEADLDVAEATPGGAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: ASSY_STAAE
Sequence: MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT1_MOUSE
Sequence: MGLWALLPSWVSTTLLLALTALPAALAANSSGRWWGIVNIASSTNLLTDSKSLQLVLEPSLQLLSRKQRRLIRQNPGILHSVSGGLQSAVRECKWQFRNRRWNCPTAPGPHLFGKIVNRGCRETAFIFAITSAGVTHSVARSCSEGSIESCTCDYRRRGPGGPDWHWGGCSDNIDFGRLFGREFVDSGEKGRDLRFLMNLHNNEAGRTTVFSEMRQECKCHGMSGSCTVRTCWMRLPTLRAVGDVLRDRFDGASRVLYGNRGSNRASRAELLRLEPEDPAHKPPSPHDLVYFEKSPNFCTYSGRLGTAGTAGRACNSSSPALDGCELLCCGRGHRTRTQRVTERCNCTFHWCCHVSCRNCTHTRVLHECL
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (By similarity).  In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (PubMed:15454084, PubMed:16116452).  Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (PubMed:2202907, PubMed:16116452).  Has a role in osteoblast function, bone development and bone homeostasis (By similarity).
What are the official names of this protein?
Proto-oncogene Wnt-1, Proto-oncogene Int-1.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: KATG_CLOBA
Sequence: MTENKCPVTGKMSKATAGSGTTNKDWWPNQLNLNILHQNSQLSNPMSKDFNYAEEFKKLDFQALKVDLYMLMTDSQIWWPADYGNYGPFFIRMAWHSAGTYRVGDGRGGGSFGLQRFAPLNSWPDNINLDKARRLLWPIKKKYGNKISWADLMILTGNCALESMGLKTLGFGGGRVDVWEPQEDIYWGSEKEWLGDEREKDDEELENPLAAVQMGLIYVNPEGPNGNPDPLGSAHDVRETFARMAMNDEETVALVAGGHTFGKCHGAASPSYVGPAPEAAPIEEQGLGWKNTYGSGNGDDTIGSGLEGAWKANPTKWTMGYLKTLFKYDWELVKSPAGAYQWLAKNVDEEDMVIDAEDSTKKHRPMMTTADLGLRYDPIYEPIARNYLKNPEKFAHDFAAAWFKLTHRDMGPISRYLGPEVPKESFIWQDPIPLVKHKLITKKDITHIKKKILDSGLSISDLVATAWASASTFRGSDKRGGANGARIRLEPQKNWEVNEPKKLNNVLNTLKQIKENFNSYHSKDKKVSLADIIILGGCVGIEQAAKRAGYNINVPFIPGRTDATQKQTDVKSFAVLEPKGDGFRNYLKTKYVVKPEDMLIDRAQLLTLTAPEMTVLIGGMRVLNCNYNKSKDGVFTNRPECLTNDFFVNLLDMNTVWKPKSEGKDRFEGFDRETGELKWTATRVDLIFGSNSQLRAIAEVYACDDNKEKFIQDFIFAWNKIMNADRFEIK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: DRD2_CANLF
Sequence: MDPLNLSWYDDDLESQNWSRPFNGSEGKPGKPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTERSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTADSPAKPEKNGHAKDHPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCECNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed:11054572).  Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity).
What are the official names of this protein?
D(2) dopamine receptor, Dopamine D2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: BSRG_BACSU
Sequence: MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system; expression in the absence of cognate antisense antitoxin SR4 RNA leads to cell lysis (PubMed:22229825, PubMed:23969414).  Induced expression causes membrane invaginations that dislocate the cell wall synthesis machinery, leading to eventual death.  Unlike many type I TA systems it does not form pores (PubMed:26234942).  Base pairing occurs between the 3' UTRs of bsrG mRNA and SR4 RNA, which leads to initiation of degradation by RNase III (rnc) followed by the action of RNase Y (rny) and RNase R (rnr).  Not toxic when expressed in E. coli (PubMed:22229825, PubMed:23969414).  When induced during logarithmic growth it only slowly exerts its toxic effect.  Expression during log growth leads to significant disturbances of cell envelope biosynthesis and cell morphology, causing cell membrane invaginations and delocalization of cell division and cell wall synthesis machinery.  Cell lysis depends on mreB, lytC and lytD, suggesting expression of bsrG triggers autolysis rather than disintegration of the membrane.  Additionally expression of bsrG also inhibits transcription (PubMed:26234942).
What are the official names of this protein?
Small toxic protein BsrG.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Fusion of GFP to the C-terminus renders the protein non-toxic but still able to associate with the membrane.
Protein: VE4_HPV11
Sequence: MADDSALYEKYPLLNLLHTPPHRPPPLQCPPAPRKTACRRRLGSEHVDRPLTTPCVWPTSDPWTVQSTTSSLTITTSTKEGTTVTVQLRL
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: SYL_SORC5
Sequence: MARRDMAAETMDPRASTEPSPNEPREPARYDHAAVEPRWQRAWEEGETFRAVRSADPARGKRYVLDMFPYPSGSGLHVGHPEGYTATDIMSRYFRMRGIDVLHVMGWDAFGLPAEQHALETGTHPADTTARNIATFKRQLKMLGFSYDWSRELSTTDPRYVRWTQWIFLQLFKKGLAYQDEVSVNWCPALGTVLANEEVIDGKSERGSHPVYRTPLRQWMLRITAYADRLAEDLRLLDWPEGTVAMQRSWIGRSEGALITFEVKGWGKGALSVFTTRPDTLMGVTYVVLAPEHPLTTWLTSAESGASEPRREAVRAYVAAAAGKSDRERLAAAAREKTGVDTGLVAVHPITGVEVPIWVADYVLGGYGTGAVMAVPGHDERDFSFARTYGLPIVEVVSPDGSLHDQLEAAYVDPGVAVRSGEFDGLATEECKRAVIARLEALGRGKREVNYKLRDWVFSRQRYWGEPIPIYFPVELADPQGDPRKGAAHTIRYDQPIAVDEASLPIELPPLADFRPGDDPAGPLARAVDWRFFQRDGKWYARETNTMPQWAGSCWYYLRFLDPQNDAEPFSEAAYDAWMPVDLYVGGAEHGVLHLLYARFWHKVLYDLGHVKHPEPFAKLVHQGMILGEDNEKMSKSRGNVINPDDIVRAHGADVLRMYEMFMGPLEAVKPWQSGQIQGVVRFRDRVFATCTRPLSDAMDDATSRQLHRTIKKVTGDIEGMAFNTAISAMMVFVNHLSSLPSPPREAVLRLILLVSPFAPHLAEELWRLTGHERSLSYEPWPTYDEAFCVDDVLEIPVQVNGKVRGRVMLAKAASEEEARAAALGLETVAALAAGKQLKKFIYVAGKIVNIVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E74EB_DROME
Sequence: MIMVQHLVAASAHNFASQAAASLVNVSSSSSSSSSSSSSSLSLSSSSSSSSLSSATPTPVASPVTPTSPPPAAAAPAEASPPAGAELQEDGQQAKTQEDPTMKDQDMLEKTRQEVKDPVNVEEPGAIVDTESVMARQSPSPVASTKVPESLEEISNKSPPVQEDEEESESVASDCREFKVLYNHLRQQQHHHSPSSPDKTRSTLDDVSKILWERKQQLQRSSVITAAPTLQPQQHQQPMSDIEDEETLEDVDDADADVEADAEDEELLEQYQNGYDSPLDLSLGGATSAAASAAAAASAVSRRRGRTYSGTESDDSAQCERARMRLKPERKAERSAAYKKSLMKRYYTEIPIVKQSTSPAPQQQLQQQHHLQQQQQQQPHNGSTFAGATALLHIKTEQNTLLTPLQLQQQQQQQQGLHGAAGNGGSSNGNNAHQQQQPLAIPQRPLLHNLLSGGAIHNPHHRNYTTATTGSFPPSPADSGVSDVDSSSSGGQPCADELKARLGMPPATSASAAAAAAAAAAAAAHLHTGTFLHPNLYQNNAANSLRNIWNRSVGVPDNYYGSSGAGSGGTQPGGPGNPQTPGYLTTSYFNAPTAATAAASQRGTTINGYHSLHQQQQQQQQSQQSQQQQQLAHQQLSHQQQQALHQQLSHQQQQQQQQQQQHPHSQLNGPHPHSHPHSHPHSHPHAGQHTHSTIAAAAAAAAASVVSSSSSAVAAAAMLSASAAAAATAAAAAGGSQSVIQPATSSVSYDLSYMLELGGFQQRKAKKPRKPKLEMGVKRRSREGSTTYLWEFLLKLLQDREYCPRFIKWTNREKGVFKLVDSKAVSRLWGMHKNKPDMNYETMGRALRYYYQRGILAKVDGQRLVYQFVDVPKDIIEIDCNGV
What are the official names of this protein?
Ecdysone-induced protein 74EF isoform B, ETS-related protein E74B.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UCHL_DICDI
Sequence: MSVDQELIETQKNWIPLEANPEVLTTFMQSLGVSKDWEFCDIYGIDEGLLEMVPSPCVAVILLFPITNEYEDKRYKLEKEIEEKGQVLSDKVYFMKQYIGNACGTIGVIHSVLNNANVIEFNENGFFKQFLDKTTSLSTEERAISLLKNSEIEKSHEISALQGQSNVPQEDEPVVLHFVSFVHVDGHLYELDGRKPFAINHGESSAETLLKDTANVLQKMIDEDPKEIRFNLMGLVKKPNEESEEEEEKEKEETK
What is the function of this protein?
Ubiquitin-protein hydrolase is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins.  This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or nedd8 (By similarity).
What are the official names of this protein?
Probable ubiquitin carboxyl-terminal hydrolase, Ubiquitin thioesterase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYDND_CERS1
Sequence: MHAYRSHTCTELNAAHVGQEVRLSGWVHRVRDHGGVLFLDLRDHYGITQVIADADSPAFAELETVRAEWVIRIEGRVKARDASLVNPKLATGEIEVYATGMSVLGAADELPLPVFGETDYPEETRLTYRFLDLRREKLHQNMMLRSNVVRSLRNRMWGAGFNEFQTPIITASSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLIMVAGFDRYFQIAPCFRDEDPRADRSPTDFYQLDIEMSFVEQEDVFAAVQPVIQGLFEEFGHGKRVDADWPRIAYRDAMLWYGSDKPDLRNPIKMQVVSEHFAGSGFAIFAKLLENEGTEIRAIPAPTGGSRKFCDRMNAFAQSQGLPGMGYIFWRKGDDGAMEAAGPLAKNIGPERTEAIRQQLGLGEGDAAFFLGGKPETFEAVAGRARTEIGRELGLTEENCFKFAWIVDFPMYEKDDEGKIDFSHNPFSMPQGGMEALEGDPLKVHAYQYDLACNGYELISGGIRNHKPEIMFKAFELAGYPKEEVEKRFGGMVKAFRYGAPPHGGCAAGIDRIVMLLADEANIREVIMFPMNQRAEDLLMGAPSEPTNEQLRELRLRVVPKD
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_LEGPH
Sequence: MTKELCMRCYISGRVQGVWFRASAKNLAEQLMISGWARNLADGRVEVFACGKEDKLEEFYTWLQKGPLNARVDVCTRENLPWEDYISFDVL
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: MINC_YERPP
Sequence: MSQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGANWKDLQQAVTSAGLRIVGISGCQDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPTQTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNIHIYGMMRGRALAGASGDAKCQIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: PPNP_ACIAC
Sequence: MTTEKIDGVSVTARANVYFDGKCVSHGITFPDGTKKSVGVILPATLTFNTGAPEIMECVGGACEYKLDGTDAWVKSGEGDKFSVPGNSKFEIRVTEAYHYICHFG
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: RS27_HALS3
Sequence: MSGGFYNVECPDCENEQTVFGKASTEVACAVCGTTLARPTGGEADLLGEVIETVEAR
What are the official names of this protein?
30S ribosomal protein S27e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.