PharMolix/UniProtQA huggingface dataset:
Protein: UGTP_BACAN
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIKDVIVCDLFGESHPVITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKLLLQAEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKKVMVDIGVPAEQIVETGIPIRSSFELKINPDIIYNKYQLCKNKKILLIVAGAHGVLGSVKELCQSFMSVPDLQVVVVCGKNEALKQDLVGVQETNPDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDMKLLQMKEAMKSIYRPEPADHIVDTILAENHVEPNHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: KATG_PYRTR
Sequence: MSQGECPVKKVPNVAGSGTRNTDWWPNELRTNILRQHDPRQNPLGPDFNYVEEFKKLDYDALKKDLNALMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRVTDGRGGGGDGQQRFAPLNAWPDNVSLDKARRLLWPIKQKYGNKISWADLMLLTGNVALESMGCPTFGFAGGRADTFQSDESVYWGGETEWLGSDVRYADGAKGVKGEGIMDGDQHKTDKSEPHTSRNLEQPLAAAHMGLIYVNPEGPEGIPDPVAAAHDIRTTFGRMAMNDAETAALIIGGHSFGKTHGAAPSENTGPDPNSEDLATQGFGWMNKHGRGNGPDTITSGLEVTWTGTPTKWSNKYLEYLYKFEWELEKSPAGANQWVAKTDEHIIPDAYDQNKKHKPRMLTTDLAMRMDPAYEKITRRWLEHPQELHDTFVRAWFKLLHRDMGPRSRWLGPEVPKEVLIWEDPVPQPEGELIGESDIATLKKQVLDAGVEPAKLIRTAWASAASFRGSDKRGGANGARIRLAPQKDWEVNNPKELAEVLKALEGVQSKFNSGSKKVSLADLIVLAGTAAVEKAAGVQVPFTPGRTDATQEQTDAKSFEHLEPVTDGFRNYGKGTDRVRTEQLDVDKAHLLRLTAPEMVVLTGGMRALNANWDGSSHGVFTKRPGQLTNDFFVNLLDNNLEWKAADSSKELYEGFDRKSGQKKWTATRHDLVFGHHPELRAVAETYAQADNTDKFVKDFVAGWEKIMNNDRFDIKNKSVSAQSRGANKPRL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR52_HUMAN
Sequence: MNESRWTEWRILNMSSGIVNVSERHSCPLGFGHYSVVDVCIFETVVIVLLTFLIIAGNLTVIFVFHCAPLLHHYTTSYFIQTMAYADLFVGVSCLVPTLSLLHYSTGVHESLTCQVFGYIISVLKSVSMACLACISVDRYLAITKPLSYNQLVTPCRLRICIILIWIYSCLIFLPSFFGWGKPGYHGDIFEWCATSWLTSAYFTGFIVCLLYAPAAFVVCFTYFHIFKICRQHTKEINDRRARFPSHEVDSSRETGHSPDRRYAMVLFRITSVFYMLWLPYIIYFLLESSRVLDNPTLSFLTTWLAISNSFCNCVIYSLSNSVFRLGLRRLSETMCTSCMCVKDQEAQEPKPRKRANSCSI
What is the function of this protein?
Gs-coupled receptor activated by antipsychotics reserpine leading to an increase in intracellular cAMP and its internalization (PubMed:24587241).  May play a role in locomotor activity through modulation of dopamine, NMDA and ADORA2A-induced locomotor activity.  These behavioral changes are accompanied by modulation of the dopamine receptor signaling pathway in striatum (PubMed:24587241).  Modulates HTT level via cAMP-dependent but PKA independent mechanisms throught activation of RAB39B that translocates HTT to the endoplasmic reticulum, thus avoiding proteasome degradation (PubMed:25738228).
What are the official names of this protein?
G-protein coupled receptor 52.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_STRT1
Sequence: MKQLTSAQIRQMWLDFWKSKGHAVEPSANLVPVNDPTLLWINSGVATLKKYFDGSVIPENPRITNSQKAIRTNDIENVGKTARHHTMFEMLGNFSVGDYFRDEAIEWGYELLTSPEWFDLPKDKLYMTYYPDDKDSYNRWIACGVEPSHLIPIEDNFWEIGAGPSGPDTEIFFDRGEEFDPDNIGIRLLEEDIENDRYIEIWNIVLSQFNADPAVPRSEYKELPNKNIDTGAGLERLAAVMQGAKTNFETDLFMPIIREIEKMSGKAYDPDGETLSFKVIADHIRSLAFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGISDAFLYKLVPTVGQIMESYYPEVLEKRDFIEKIVKREEETFARTIDAGSSMLDELLANLKKSGKDTLEGKDIFKLYDTYGFPVELTEELAEDEGFKIDHEGFKAAMKEQQDRARASVVKGGSMGMQNETLANITEPSEFLYEAETAESRLSVIVADDARHDSVNSGQALLVFEQTPFYAEMGGQVADHGTISDAAGTTVARVVDVQRAPNGQALHTVEVEGELVVGANYKLEIDHSRRHRVMKNHTATHLLHAALHNIVGNHAVQAGSLNEQEFLRFDFTHFEAVTPEELRAIEEQVNEEIWKATPVTTIETDIDTAKSMGAMALFGEKYGKRVRVVSIGDYSVELCGGTHVANTAEIGMFKIIKEEGIGSGTRRILAVTSREAYLAYREEEDALKSIAATLKAPQLKEVPNKVASLQEQLHALQKENATLKEKAAAAAAGDVFKDVKEANGVRYIASQVEVSDAGALRTFADQWKQADYSDVLVLAAHIREKVNVLVASKSENVHAGNLIKVLAPIVSGRGGGKPDMAMAGGSDANSIQDLLSAVAEQF
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRM2_HUMAN
Sequence: MAGYLKLVCVSFQRQGFHTVGSRCKNRTGAEHLWLTRHLRDPFVKAAKVESYRCRSAFKLLEVNERHQILRPGLRVLDCGAAPGAWSQVAVQKVNAAGTDPSSPVGFVLGVDLLHIFPLEGATFLCPADVTDPRTSQRILEVLPGRRADVILSDMAPNATGFRDLDHDRLISLCLTLLSVTPDILQPGGTFLCKTWAGSQSRRLQRRLTEEFQNVRIIKPEASRKESSEVYFLATQYHGRKGTVKQ
What is the function of this protein?
S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methyluridine at position 1369 (Um1369) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a universally conserved modification in the peptidyl transferase domain of the mtLSU rRNA.
What are the official names of this protein?
rRNA methyltransferase 2, mitochondrial, 16S rRNA (uridine(1369)-2'-O)-methyltransferase, 16S rRNA [Um1369] 2'-O-methyltransferase, Protein ftsJ homolog 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
Protein: HPRK_LISW6
Sequence: MTKSVTVKDLKERLNLELICSETGLERPILTSDLSRPGLELTGFFSYYPEDRVQLFGMTEISFSEGMEPEERLKRYKQMCTKRTPAFVISRNLEVPKELVAAAKEADIPVLRSRLKTTRLSVYITNYLESRLAPVISMHGVLVDIYGLGVLITGSSGVGKSETALELVKRGHRLVADDNVEIRQEDELTLIGSSPAIIEHLLEIRGLGIINVMTLFGAGAVRSSKKITIVVHLENWDPDKHYDRVGLDQEKTKIFDMDIPKITVPVRPGRNLSVIIEVAAMNFRLKNMGYNAAEQFTQDLNNLIGHNSSMND
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: VF050_IIV6
Sequence: MIELKLKNFKCFENKTFNFKDEMVLISAPSGSGKTSILSAIKFALWGSGKTLTKGEIMHGKNSCSVTLTYNDITIQRTKRPNRLVYTKQNEIYEDNEAQIYINEYFGNQSHNNFLESSSLDKTEYLEKMAFGKSTEIIELMKENTKENIRSINDETNNTEGQLSLTKKLLKSVINDWNNRMCSIVEPQIPQIPVFENKVLNVSIYEEKDNIEKEIESLKLKNINHSILKSKLETILKQKCDLMNQIQNVKNNIDVTKNNLIYLNDLSTVSIDDLQEKINKINHEKKILNEKHTKILIEKSNLQNFLNETNTLNQKLTELKIKKENLTPTIVLSSENEQSTQSFSLLKTRETHELNSLKTTLQNDISCMTEIMLKESVCKSQTDSLKKNIVKIEDEVVRLLNITKTVNLTLMNENLSTLYQQSDHFNKIAAQKTILTTKVQNINIEKSKIEEKMVKTQKCNEDDVNKLDFKVQKLEKVKSFNKYLNSIKEHLKQSFPGVETLEFTGHKSQLSVIKDFFEDALYTQKLGDKAPKYKCPKCLHPLSIQHKNDKINIVSYIDEYILEILVKVNELLSEYNNETTIEVMDDEEIENIKDFKKLILEREAFQIQIKKLEEEIKNLPVLYDKSNEIQSLQNTIASYNANNIQLLKEETKLKEEKKLLTQNITMSKLIHEESNKIKDTYKIMIGIDKDITNENIQTYLKKELSDLESELKERLIFETNLLIYNDIVSQIKTILDRQTIITEEIATIKKFIEEHSNIDELIDNLNQEHNLCYTNLLNKHKYEQYNTQLLNYINLCVEYNESLNKVETDMETLKDQLKDDEKCCLELQKLQEYMKQIESFIKIQKKYELELNKFNEWTKLKNEYKKSVSNYETIINDLENRLLKLNNEYSASITLKLKISEAQNIALTSLVDTINIYVQQFLDLFFEEPIVINLTMFKETDKKGLKATPRYQPKVTVNLYYKGVLCPSDLSSLSSGEYARVSLAFTLAFHQINNNKVTPLMLDERTANLDQDLSTLIYSVIKENFPNQLLLVVAHQVITGPFDNIITLQDYN
What are the official names of this protein?
Uncharacterized protein 050L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 050L family.
Protein: MCHE_ECOLX
Sequence: MFRQDALENRKMKWQGRAILLPGIPLWLIMLGSIVFITAFLMFIIVGTYSRRVNVSGEVTTWPRAVNIYSGVQGFVVRQFVHEGQLIKKGDPVYLIDISKSTRSGIVTDNHRRDIENQLVRVDNIISRLEESKKITLDTLEKQRLQYTDAFRRSSDIIQRAEEGIKIMKNNMENYRNYQAKGLINKDQLTNQVALYYQQQNNLLSLSGQNEQNALQITTLESQIQTQAADFDNRIYQMELQRYELQKELVNTDVEGEIIIRALTDGKVDSLSVTVGQMVNTGDSLLQVIPENIENYYLILWVPNDAVPYISAGDKVNIRYEAFPAEKFGQFSATVKTISRTPASTQEMLTYKGAPQNTPGASVPWYKVIAMPEKQIIRYDEKYLPLENGMKAESTLFLEKRRIYQWMLSPFYDMKHSATGPLND
What is the function of this protein?
Probably involved, in conjunction with MchF, in the secretion of microcin H47.
What are the official names of this protein?
Microcin H47 secretion protein MchE.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HXT3_YEAST
Sequence: MNSTPDLISPQKSSENSNADLPSNSSQVMNMPEEKGVQDDFQAEADQVLTNPNTGKGAYVTVSICCVMVAFGGFVFGWDTGTISGFVAQTDFLRRFGMKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVGMSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGVTRLWPNGEGNGSSKGAGNCMIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNDMYAEGVLPWKSASWVPTSQRGANYDADALMHDDQPFYKKMFGKK
What is the function of this protein?
Low-affinity glucose transporter.
What are the official names of this protein?
Low-affinity glucose transporter HXT3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GRPE_PHOLL
Sequence: MSSKEQKMPDEQVSEDMEVVSEQQNSADKAEASETESVVDPRVAELEEQLKQAQQRERDAILRAKAEVENIRRRTEQDVEKAHKFALERFANELLPVIDNLERALEVADRTNTEIAPMVEGIELTLKSFLGAVGKFGIEVVGDTNVPFNPEIHQAMTMMESDQHEPNHVMMVMQKGYTLNGRLLRPAMVAVSK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_TOLAT
Sequence: MKDLLKFLKAQSKTEEFDGIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLLLDMTLRDIERVLYFESFVVVDAGMTSLERSQMLTEEQYLDALEEYGDEFDAKMGAEAILALLRAQDLEHEIATMREELSQTNSETKRKKTTKRLKLMESFLQSGNKPEWMIMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLETRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCSAFNADFDGDQMAVHLPLTLEAQLEARALMMSTNNILSPASGEPIIVPSQDVVLGLYYMTRSCVGAKGEGMVLSGAKEAEKIYRAGLASLHARVKCRITEYVKNEAGELVPKIELKNTTVGRAILSLILPKGMEYALIDPPLPMTEAGKAELAEHPERWIKYVSNQAMGKKQISKVLNTCYRKQGLKDTVIFADQLMYTGFHYAALSGSSVGIDDMVIPDAKKDIIAAAEAEVAEIQEQFQSGLVTAGERYNKVIDIWASANERVSKAMMENLSKETRQNSLGEDEVQASFNSVFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDVVITELDCGTSEGLWMTPLIEGGDVVEPLRERVLGRVVAEDVLKPGTEDVLVARNTLLDEQWCNTLERNSVDRVKVRSAIACESDFGICAHCYGRDLARGHLVNNGEATGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSASVKNTGVIKLQNAKSVENSAGKLVITSRSSELTIMDELGRTKESHKLPYGSVLEVKDGQAVKAGEIVANWDPHTHPIITEVAGRIQFENMIEGITITRQTDELTGLSSIVVLDVNERTTTGKELRPTVKLVDANGKDVLIPGTDVAAQYFLPGQAIVQLEDGAQVNVGDAVARIPQASSGTKDITGGLPRVADLFEARQPKEPAILAEISGTISFGKETKGKRRLVITPTDGGDAHEEMIPKWRNLNVFEGEKVQQGEVLADGPESAHDILRLRGISPVANYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKCEIVNPGDSDLLEGEQADVVRVKIANRKLVAEGKQPATFRRVLMGITKASLNTESFISAASFQETTRVLTEAAVSGKVDDLRGLKENVIVGRLIPAGTGFAYHHGRLEKRRQAAKAVVPVTQQATADEAEQNLADLLNAADNLNA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: HPCH_SALG2
Sequence: MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEARNAVAATRYPPAGIRGVGSALARASRWNRIPDYLHQANDAMCVLVQIETREAMSNLASILDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEALAKRYLELGALFVAVGVDTTLLARGAEALAARFGAEKKLSGASGVY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
What are the official names of this protein?
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, HHED aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, HKHD aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: ENO_FRATH
Sequence: MSSQIKQVFARQILDSRGNPTVEVDVVLESGAFGRAAVPSGASTGIREALELRDGNKALFIGKSVYKAVENVNTKIAQAVKGLDALDQRLIDKTMIELDGSENKKNLGANAILGVSLATARAAASHLRKPFYRYLMDVKEYLMPVPMMNVINGGSHADNNVDMQEFMIVPAGFDTFSEALRCGTEVFHTLKKVLIADGYSVAGVGDEGGYAPDLPSNEAAIEAILKAVKEAGYEPGKHVFIALDPASSEFYKDGKYELKSENKSLTTEEMIDYYAAWVEKYPIVSIEDGLAEEDWAGWKLLTEKLGNKVQLVGDDLFVTNPSILAKGIEKGIANSILIKLNQIGTLTETFEAMAMAGQAGYTCVVSHRSGETSDTIIADLAVATCSGQIKTGSLSRSDRIAKYNQLLRIEEELGENAIYPGIKAFVFNSDEEVEEVVQEIIVEDSEAEKVVVQVEE
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: APT_HALOH
Sequence: MELKKFIRDIPDFPKKGIIFKDITPLLKDKEAFNLAIEKMKDYYKDFDIDYIVGIEARGFIIGTPLALALNKGFIPIRKPGKLPAERISTSYELEYGTNEIEIHRDAIQPGDKILLVDDLLATGGTVKAAIELINKLQGEIVSLGFLIELVDLKGREKLEGYDVFTLLQE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_STAAB
Sequence: MAKQDVIELEGTVLDTLPNAMFKVELENGHEILAHVSGKIRMNYIRILPGDKVTVEMSPYDLTRGRITYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_HYPNA
Sequence: MSHNPIRPWRNIERRKSRQVRVGNLMVGGDAPIAVQTMTNTPTEDAAATIAQILRCAEAGADIVRVSCPTEESTKAMREIVKASPVPLVADIHFHYKRGIEAADAGAACLRINPGNIGSHARVKEVVAAARANGCSMRIGVNGGSLERHLLEKYGEPCPDAMVESALDHARILDDLGFYDYKISVKASDMFLTVAAYHALAEATDAPLHLGITEAGGLRTGTVKSSIGMGALLWAGIGDTIRVSLSAEPEEEVKVGFEMLKSLGLRTRGVNIVACPSCARQGFDVIRTVETLEKRLAHISEPISLSIIGCVVNGPGEASLTDLGFTGGGKESGKMFVNGRADHNVANADMVEHIVKLVEDKAARLKAQRDAEEATEVPAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RECU_LACCB
Sequence: MTIHYPNGNPYKDGTQFSSQAISRPTIYGGRGMTLEEELNISNQYYRSIDKAVVYKKPTPVQIVKVDYPKRSQAVIREAYFKTPSTTDYNGVYRGFYLDFEAKETKNKASFPLKNFHQHQIEHFRRCLKQSGICFVVIRFATLKRLFVFPAGRLIDCWDRQPDGGRKSIPLKDIVTNGFELHPQLQPVIPFLDGVDWLIETKVGNVRG
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_STRAW
Sequence: MARHLITSALPYINGIKHLGNMVGSMLPADVYSRYLRQRGHDVLYICATDEHGTPAELAAKERGLPVDEFCAQAHDAQKAVYDGFELAFDYFGRSSSEQNREITQHFARRLNENGFIEERAIRQVYSPADGRFLPDRYVEGTCPHCGYDKARGDQCENCTRVLDPTDLINPRSAISGSTDLEVRETKHLFLLQSKLQHEVEEWVARHEEEWPQLASSIARKWLNEGLHDRAITRDLDWGVPVPADTWPELAAEGKVFYVWFDAPIEYIGATKEWSDLDPENRDWKSWWYDADSGENPVRYTEFMAKDNVPFHTVMFPATELGVREPWKKVDYVKAFNWLTYYGGKFSTSQKRGVFTDHALEILPADYWRYFLIANAPESDDSSFTWEHFTATVNKDLADTLGNFVNRVLSFSKKRFGEEVPAGAPAGESETKLGEEIAALLAEYESHMETLQFRKAAAALRALWSAGNSYLEEKAPWLEIKTNPEGAALTLRTAMNLIHLYSVVSEPFIPASSKAMRSAFALSEDTATWVTQDEAKSLDSVPAGTPFTVPPVLFAKITDEDLESYKERFGGAPE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I97A1
Sequence: MEDFVRQCFNPMIVELAEKTMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRAMAWTVVNSICNTTGVDKPKFLPDLYDYKENRFTEIGVTRREVHIYYLEKANKIKSEETHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSQGPCVGLPTKVSHLTSPALKTLEPMWMDLNRTAALRASFLKCRKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: NANE1_STRR6
Sequence: MSQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIYTPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase 1, ManNAc-6-P epimerase 1.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: HUTI_PSEF5
Sequence: MKTLWQHCNVASMASGVYSIIEDAAMVTSGAHIEWIGRRSEAPAGDYAQVNDLAGAWVTPGFIDCHTHTVFGGNRSGEFEQRLQGVSYAEIAAAGGGIASTVRATRAATEEELFGSARKRLLSLLRDGVTSVEIKSGYGLDLASERKILRVIRRLGEELPVSVRSTCLAAHALPPEYAERSDAYIEHICSDMLPALAAEGLVDAVDAFCEYLAFSPEQVERVFIAAQQLGLPVKLHAEQLSSLHGSSLAARYHALSADHLEFMTEEDAIAMAASGTVAVLLPGAFYFLRETQQPPMEALRKHGVKIAVASDLNPGTSPALSLRLMLNMACTCFRMTPEEALAGVTLHAAQALGMEKTHGSLEVGKVADFVAWQIDRPADLAYWLGGDLEKRVVRHGVEVTV
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYT_HOPST
Sequence: MLHSQLPVAAPLRLLCALLLLPSVTMIPGGLSPRSVTDPDVQEAAEFAVQEYNALSANAYYYKQLRIVEAQSQVVTGAKYYLTMELMKTKCAKTTGKPKVYKEIQNCELPPKAQQEKLTCRFQVWSRPWLEKIELTKMSCN
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as a housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.