PharMolix/UniProtQA huggingface dataset:
Protein: CGL_BOVIN
Sequence: MQEKEASPHGFLPRFQHFATQAIHVGQEPEQWTSQAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYSLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVATEFGLKISFVDCSKPKLLEAAITPETKLVWIETPTNPSLKMIDIEACAHTVHKHGDIILVVDNTFMSAYFQRPLSLGADICMYSATKYMNGYSDVVMGLVSLNSESLHDRLRFLQNSLGAVPSPIDCYLCNRGLKTLQVRMEKHFENGMAVAQFLESNPQVEKVIYPGLPSHPQHELAKRQCTGCPGMVTFYIKGSLQHAETFLQNLKLFTLAESLGGYESLAELPAIMTHASVPKSDREVLGISDTLIRLSVGLEDKQDLLDDLDQALKAANPPNASSN
What is the function of this protein?
Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine.  Has broad substrate specificity.  Converts cystathionine to cysteine, ammonia and 2-oxobutanoate.  Converts two cysteine molecules to lanthionine and hydrogen sulfide.  Can also accept homocysteine as substrate.  Specificity depends on the levels of the endogenous substrates.  Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure.  Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function (By similarity).
What are the official names of this protein?
Cystathionine gamma-lyase, Cysteine-protein sulfhydrase, Gamma-cystathionase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPS2_MOUSE
Sequence: MLDPSSSEEESDEGLEEESREVLVAPGVSQRAPPAAAREGRRDAPGRSGGGSGGGAARPVSPSPSVLSEGRNEPELQLDEEQERRIRLQLYVFVVRCIAYPFNAKQPTDMARRQQKLNKQQLQLLKERFQAFLNGETQIVADEAFCNAVRSYYEVFLKSDRVARMVQSGGCSANDFREVFKKNIEKRVRSLPEIDGLSKETVLSSWIAKYDAIYRGEEDLCKQPNRMTLSAVSELILSKEQLYEMFQQILGIKKLEHQLLYNACQLDNADEQAAQIRRELDGRLQLAEKMAKERRFPRFISKEMESMYIEELRASVNLLMANLESLPVSKGGPEFKLQKLKRSQNSAFLDLGDENEIQLSKSDVVLSFTLEIVIMEVQGLKSVAPNRIVYCTMEVEGGEKLQTDQAEASRPQWGTQGDFNTTHPRPVVKVKLFTESTGVLALEDKELGRVVLYPTSNSSKSAELHRMTVPKNSQDSDLKIKLAVRMDKPAHMKHSGYLYALGQKVWKRWKKRYFVLVQVSQYTFAMCSYREKKSEPQELMQLEGYTVDYTDPHPGLQGGQVFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSYKPVPAVQSQKLNPKGGALHADAQLYADRFQKHGMDEFISASPCKLDHAFLFRILQRQTLDHRLNDSYSCLGWFSPGQVFVLDEYCARYGVRGCHRHLCYLTELMEHSENGAVIDPTLLHYSFAFCASHVHGNRPDGIGTVSVEEKERFEEIKDRLSSLLENQISHFRYCFPFGRPEGALKATLSLLERVLMKDIATPIPAEEVKKVVRKCLEKAALINYTRLTEYAKIEETMNQATPARKLEEVLHLAELCIEVLQQNEEHHAEGREAFAWWPDLLAEHAEKFWALFTVDMDTALEAQPQDSWDSFPLFQLLNNFLRNDTLLCNGKFHKHLQEIFVPLVVRYVDLMESAIAQSIHRGFEQETWQPVKNIANSLPNVALPKVPSLPLNLPQIPSFSTPPWMASLYESTNGSTTSEDLFWKLDALQMFVFDLHWPEQEFAHHLEQRLKLMASDMIEACVKRTRTAFELKLQKANKTTDLRIPASVCTMFNVLVDAKKQSTKLCALDGGQEQQYHSKIDDLIDNTVKEIIALLVSKFVSVLEGVLSKLSRYDEGTFFSSILSFTVKAAAKYVDVPKPGMDLADTYIMFVRQNQDILREKVNEEMYIEKLFDQWYSNSMKVICVWLADRLDLQLHIYQLKTLIKIVKKTYRDFRLQGVLEGTLNSKTYDTLHRRLTVEEATASVSEGGGLQGITMKDSDEEEEG
What is the function of this protein?
Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides.  Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles.  Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development.  May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles.
What are the official names of this protein?
Calcium-dependent secretion activator 2, Calcium-dependent activator protein for secretion 2, CAPS-2.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Note=Membrane-associated to vesicles. Strongly enriched in synaptic fractions. Probably localizes to different vesicles compared to CADPS. Enriched on vesicular structures in the parallel fiber terminal of granule cells that are distinct from synaptic vesicles.
Protein: MDTJ_SALPA
Sequence: MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKGAARATI
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS11_BURCH
Sequence: MAKASNTAAQRVRKKVKKNVAEGVVHVHASFNNTIITITDRQGNALAWATSGGQGFKGSRKSTPFAAQVAAESAGRVAMEYGVKNLEVRIKGPGPGRESAVRALHGLGIKITAISDVTPIPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TARGB_BPD10
Sequence: MNISDIRAGLRTLVENEETTFKQIALESGLSTGTISSFINDKYNGDNERVSQMLQRWLEKYHAVAELPEPPRFVETQTVKQIWTSMRFASLTESIAVVCGNPGVGKTEAAREYRRTNNNVWMITITPSCASVLECLTELAFELGMNDAPRRKGPLSRALRRRLEGTQGLVIIDEADHLGAEVLEELRLLQESTRTGLVLMGNHRVYSNMTGGNRTVEFARLFSRIAKRTAINKTKKADVKAIADAWQINGENELELLQQIAQKPGALRILNHSLRLAAMTAHGKGERVNEDYLRQAFRELDLDVDISTLLRN
What is the function of this protein?
Selects the target DNA sites for transposition.  Recruits DDE-recombinase A to the target sites and catalytically activates it.  Displays non-specific DNA-binding properties.  Polymerizes as helical filaments around the DNA.  Coating of the DNA by the target DNA activator B might play a role in favoring target-primed replication over integration.  Prevents self-integration into an integrated copy of the viral genome.  This mechanism is called target immunity and is achieved by two mechanisms: first, the target DNA activator B dissociates from the viral genome ends upon interaction in cis with DDE-recombinase A, which makes the viral genome ends a poor target for new insertions.  Second, the interior of the viral genome may also be protected from integration events by the target DNA activator B being strongly bound throughout the whole viral genome (By similarity).
What are the official names of this protein?
ATP-dependent target DNA activator B, Gene product B, gpB, MuB.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RS21_DICNV
Sequence: MPSVKVRDNEPFDVAMRRFKRSCEKAGVLAEVRSREFYEKPTQERKRKLAAAVKRNSRRLKKERSRFERLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS8_PARPJ
Sequence: MSMSDPIADMLTRIRNAQMVEKVSVTMPSSKVKVAIAQVLKDEGYIDDFAVKSEGAKSELNIVLKYYAGRPVIERIERVSKPGLRVYRGRNDIPVVMNGLGVAIVSTPKGVMTDRKARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: EXO70_EMENI
Sequence: MVAPRDTAFAEESAEVEVLYANLEKLKRLTKKIQGSLVRLETGGNVVKHAIGPIYSNTQSLQITNNNIDRVIEAIERLRQPLDAKNREEGVIRAGPQPNNLPQYLAAMRGVNDALMDLTSTNLKSNQKAISEFTSLLGIGNSKLQDLLRLKLGEHVSPIEPLHYLTKDLPFPTIPEDRIAEIAPICAAINSAAVHVPHRGEGGSPALKIYADVRGPYISTSAQNLAIASLNTLKRRVDDESPYKQGTNGIGTYSDALENFIYAEWEAIKRIFTGDHRGLALQMTCRSAIAEYSKTIRELNDYIRTNLLTDCFLAFEIIDIVTAKSYDIELKTGELKSLFLEALRPVRETAKYSLAELLEETKRRAQAIPMLPPNGAPTPLVDKVMRSLIELTGYQKPLASILTSLGDGNWRSTSASSMNTPLDVNPDSDVLFSHFILDVIETLLIALEARARQLHRTKAAQGVFLSNVFCLVDRAIRSSPELARFLGSPDSVSRIDTFRKRATSTYLDAWKETSHYLLDVQYTSHTRGGSRPQSGGAVDSSAIVKSLSSRDKDAIKDKFKAFNASFDDLVARHKSFYMEREVRSVLAREVQAVLEPLYARFYDRYHELDKGRGKYTKYDKGSLSAQLASLQ
What is the function of this protein?
Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis.  Also plays a role in the assembly of the exocyst (By similarity).
What are the official names of this protein?
Exocyst complex protein exo70.
What is the protein family that this protein belongs to?
Belongs to the EXO70 family.
What are the subcellular locations of this protein?
Bud. Bud neck.
Protein: URED_RHOPS
Sequence: MQTESSRREAAAATEQLFAANRAQGSVQFDVRAVDGVTRRGKLHESGSLRVRFPSPEQQGLSAVLVNTAGGVAGGDRFSIDIAVGESARLTLTTAAAEKIYRSHGPSAQLDITLKVADDGHLGWLPQETILFDQARVERRIDIELAPRASLLLCESVIFGRSAMGETMRHGRFIDRWRLRVGGKLVFAETVRLDGEIGALLDRPAVAKGGVAVGTALIAPGDSELVERLRENADLFGAEVGITAWNGIAMARFCAQDAARLRADMMAVLRRAAGRALPRLWLS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP1_SOLTU
Sequence: MKAGALELGHASKTTKSGVNRGMSILDLFIRIIAIIATLGSAIAMGTTNETLPFFTQFVRFKAKYSDLPTFTFFVVANAIVSAYLVLSLGLSIYHIMRSRAQATRIALIFFDAAMLGLLTGGASASAAIVYLAHKGNRKTNWFPICQQYDSFCHRTSGSLVGSFAGSVLIILLIFLSAIALSRQSLNH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, StCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: ATP6_BUCAI
Sequence: MILEKISDPQKYISHHLSHLQIDLRSFKIIQPGALSSDYWTVNVDSMFFSLVLGSFFLSIFYMVGKKITQGIPGKLQTAIELIFEFVNLNVKSMYQGKNALIAPLSLTVFIWVFLMNLMDLVPIDFFPFISEKVFELPAMRIVPSADINITLSMSLGVFFLILFYTVKIKGYVGFLKELILQPFNHPVFSIFNFILEFVSLVSKPISLGLRLFGNMYAGEMIFILIAGLLPWWTQCFLNVPWAIFHILIISLQAFIFMVLTIVYLSMASQSHKD
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YIDC_AGRVS
Sequence: MMENNRNYLIAIALSVMVVLGWQFFYMNPRIEAQRQAEQAQQAQQAKTPATQATPGAAVNGALPGQTQASATTSREDAVAKSARVEINTEALSGSINLTGARLDDLRLKGYHETVDKTSPIITLLNPADTKDGYFAEIGFIGGEKSGSVPGPSTVWTVKDGQTLTETTPVTLTYTNETGLTFSRKISVDKHYMFTIEDTVANAGGADISLAPYGRVTRYNKPAVASTYVLHEGFIGVMGSGDGKFASVEAKYAAIEKENETNAKATGGWLGITDKYWAATLVPPQSLAYDSRFSHFTDGQARFQADYKNDPVTIAPGQSTTLKTLLFAGAKEVPVVDGYALDKSWFGQAFTNLFAGAKDTVQQYDIPRFDLLIDWGWFYFLTKPMFKLMDFFFRQVGNFGVAILLTTIAVKLLFFPLASKQYASMANMKRMQPKMEELKAKHGDDRMALQQAMMELYKTEKINPVAGCWPLLLQIPVFFALYKVIYITIEMRHAPFFGWIHDLSAPDPTSFVNLFGLLPFESPAMLHLGIWPIIMGITMFVQMRMNPTPPDPTQAMLFNWMPLVFTFMLGSFPAGLVIYWAWNNTLSVLQQSIIMKRHGVKIELFDNLKGLFQRKSAKTK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDRP_WOLWR
Sequence: MTLKKLNLHLVSDSSGETVISVAKSALKHFRSVETIEYVWSFVKGEEQIDKILEEINRKSDEHNFVICTITDDELRKYLKDNCIKLKIPYRAILSHIIREISSYLEIEKDEKLDLHTEINNEYFQRIEAINYTINHDDGQNIQDIDKADIILVGVSRTSKSPTSTYLAYRGYKVANIPFVSGVPFYVDLAKLKNKLTIGVTIDVSRLIEIRKNRLTSINNEDNNIYANPEKVEKEIKEAEELFKQNNWPIIDVTQKSIEEVSATIIQYFNKMLSID
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RECR_FRATH
Sequence: MTSKIFSPKISAVIESLRKLPTIGKKSSQRLALYLLDKSPETAIAIANSLLDATANIKKCVYCQALTEDDVCNICSNTNRDDTKLCIIESMLDMIAIEEAGIYRGKYFVLNGRISPLDGIGPSELKLDILQQIIADRKIDEVILAISPTVEGETTAHFISQMIAKDIKISRIGFGVPFGGELEYLDQQTLLHAFNTRTNI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MRAY_MARN8
Sequence: MLLWLTEILSQYFSSLTVFQYLTLRAILGILTALLISLVIGPVMIRKLSQYQIGQAVRDDGPQTHLSKAGTPTMGGALILVAIAISTLLWADLTNRYVWVVLLVTLLFGAIGWVDDYRKVVERNPRGLPARWKYFWQSVIGATAAIVLYVTASMPQETSLYLPFLKNVSLTLGPVLFILLTYFVIVGSSNAVNLTDGLDGLAIMPTVMVAGALAIFAYLSGHAQFANYLLIPHLPGTGELIIFCGALVGAGLGFLWFNTYPAQVFMGDVGALALGAALGTVAVIVRQEIVLFIMGGVFVMETISVILQVASFRLTGRRIFRMAPLHHHFELKGWPEPRVIVRFWVVTVVLVLIGLASLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUF3_SCHPO
Sequence: MFTAVNSNPNASESISGNSAFNFPSAPVSSLDTNNYGQRRPSLLSGTSPTSSFFNSSMISSNYTFPHGSNKQASLESPVSYSNPIPSLTWLSLDGDSPDSLVSTPTAPSANHHGNPFPNGKQSIKAMPSLVNLQEDSVISKFPNSLEVPFRKRSESTSSSLSGLHSDLRPLKTELYGQLNSECGARFPQTLKSPLTPIGGDSARTVSASTARTSDKFFPRHTRAHSDFWIPATSKPSRHASHSSIGDLTTITQSSISSGSGSFKPSWDGSFDSSLMAHQSYGTSPAFANGNSPTLKNDSSFFGSASVRPTVSPIGTSFRQSLPDISAFGIPKTETNPSEVVAPGTIPISVLPTSNFSAATPANPSLINQNGQEFLQQSRVLYLFHANKQRHFELSDILGNVVLFSTDQHGSRFIQQKLATATEEEREAVFQEIASTSCLQLMMDIFGNYVVQKYFEFGNEKQKQILLSQIKGHVFSLSLQMYGCRVVQKAIEYISPEHQVQLIQELDGHVLDCVCDQNGNHVIQKAIECIDTGHLQFILRALRPQIHVLSAHPYGCRVIQRAIEHCHSERKLIIEELLPHILKLTQDQYGNYVVQHILRTGSESDKKYIFDLMIDHLLFLSCHKFASNVVERCISYISDVDRRRILNKIISEKAENCSILMLMMKDKYANYVIQKLLDASPEEERDLLISYIYPHISVLKKFTYGKHLIMSVERFRQKSISAVPKLASKECK
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation.  Predominantly binds to mRNAs encoding mitochondrial proteins and localizes them to the vicinity of mitochondria for translation.  Regulates mitochondrial biogenesis, motility and morphology (By similarity).
What are the official names of this protein?
mRNA-binding protein puf3, Pumilio homology domain family member 3.
What is the protein family that this protein belongs to?
Belongs to the PUF3 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Localizes to multiple discrete foci in the cytoplasm.
Protein: COAX_MARN8
Sequence: MILLIDAGNTRLKWRLAGTGGPLEGAGVMADAEPLIGLSGYWSDIDRILVSTVASESARAQLHELLLAGAKVPVEYCWAESTRDGLSNSYGDVSRMGADRWHAMLAGWVRCKASFAVVDAGSAVTVDYVNAGGRHLGGYILPGLQMMRRSLKVDAARIGFEQSEQLDTRPGQSTGECVNHGLAWLTEALVQRIHRDAKAFGLSAIYLTGGDARRLQALGLEANVVEGMVLDGLERIASAGVL
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZP3_CHICK
Sequence: MQGGRVVLGLLCCLVAGVGSYTPWDISWAARGDPSAWSWGAEAHSRAVAGSHPVAVQCQEAQLVVTVHRDLFGTGRLINAADLTLGPAACKHSSLNAAHNTVTFAAGLHECGSVVQVTPDTLIYRTLINYDPSPASNPVIIRTNPAVIPIECHYPRRENVSSNAIRPTWSPFNSALSAEERLVFSLRLMSDDWSTERPFTGFQLGDILNIQAEVSTENHVPLRLFVDSCVAALSPDGDSSPHYAIIDFNGCLVDGRVDDTSSAFITPRPREDVLRFRIDVFRFAGDNRNLIYITCHLKVTPADQGPDPQNKACSFNKARNTWVPVEGSRDVCNCCETGNCEPPALSRRLNPMERWQSRRFRRDAGKEVAADVVIGPVLLSADPGAVGQQEEGGDGAAVMVPSVGTGLVCVAVAVALAAVGVAVGIARKGCTRTSAAV
What is the function of this protein?
Component of the zona pellucida, which mediates species-specific sperm binding.  Directly binds to sperm.  Important for egg fertilization.
What are the official names of this protein?
Zona pellucida sperm-binding protein 3, Sperm receptor, Zona pellucida C protein, Zona pellucida glycoprotein 3, Zp-3.
What is the protein family that this protein belongs to?
Belongs to the ZP domain family. ZPC subfamily.
What are the subcellular locations of this protein?
[Processed zona pellucida sperm-binding protein 3]: Secreted, extracellular space, extracellular matrix. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein.
Protein: RNFB_BUCAI
Sequence: MITLIIFSFLSFLLGIILSFTAYKFRSQEDPIVAIVNELLPQSQCAQCGYSGCYPYAKAIVENSEKINKCIPGGTDLISAISSVLSIEVPEKNLIITHKKQKNNTVLINESNCVGCSKCASFCPVDAIVGAPNFIHTVLQEFCTGCNICLLHCPTNCIEIKKETYEE
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: SELU_SHEPW
Sequence: MPVNMVSASEYRRILVSDHPIMDARAPVEFTKGAFPASRNHPLMEDEERRLVGTCYKQNGQQAAIDLGHSLVTGEIKQQRLDAWQRYFTKHPDAYLYCFRGGLRSKLTQQWLKEAGIDVPFIEGGYKAMRQFLIETIDNAASQNPMLILSGITGSGKTDFLLARNDSVDLEGIAHHRGSSFGRYHEPQPTQINFENALAVALLKHQDSQAKHLLLEDESFLIGRSALPQAFYKGMQQANVVVLEEPMEARLTRLLNEYVHKMHSGYIQRLGEEAGFAAFAEYLALSITGIKKRLGGKQHDEFQAIITNALNIQQSRGDTSAHIEWIELLLSKYYDPMYQYQIDKKAERILFKGDHLAMHQWLDAN
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: ALDOC_CHICK
Sequence: LLKPNMVTPGHSCPTKYSPEEIAMATVTALRRTVPPAVPGVTFLSGGQSEEEASINLNAINTCPLVRPWALTFSYGRALQASALSAWRGQRDNANAATEEFVKRAEVNGLAALGKYEGSGDDSGAAGQSLYVANHAY
What are the official names of this protein?
Fructose-bisphosphate aldolase C, Brain-type aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: RS10_STAHJ
Sequence: MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGAEVSGPIPLPTEKSVYTIIRAVHMYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: FANCJ_CHICK
Sequence: MSSDVSQYTIGGVKIMFPCKAYPSQLAMMNAIVKGLNNRQHCLLESPTGSGKSLALLCSALSWQQSLYEKSLLKSSCEKEDREPAASLPCRCVCHSRSESSEATAGASHGAACSNNYETGGSVKHGDQLSDTECKENNTLASKLSAKKRASACGNECDDFQVERKRIRPLETEQQVRKRHCFSKEVQLVDALEVYNQRKNGELIVHSEKSVKNTSPQTLFSSCTECSCSSGKETRKDSGNTKKKANGDQTFIPKIFFGTRTHKQIAQITRELKRTAYSGVPMTILSSRDYTCIHPVVSSSNSNRNELCVELLEGKHGKSCLYYHGVHKLSEHYALQSAHNTYQAWDIEDLVSLGKKLRACPYFAARELMVGADIVFCPYNYLLDPQIRESMEINLKGQVVILDEAHNIEDSAREAVSYSVTESQLNAAREELDFMVNNNIRQKDHEQLRAMCCSLTNWLRESSSQLVETGYETSCKVWSGKEMLNHFHDMGITNISFPILQKHLSAVLEKEEKISMFGKEELVEIPIVSSATQIVLKGLFMVLLYLFKDNSRFADDYRVALQQTYAWTNDNQPDVSDTSAFFTKTKHKRNLRHKTVVHMLNFWCLNPAVAFSDLNDVRTVVLTSGTLSPMDSFSSELGVKFSIQLEANHVIRNSQVWVGTIGTGPNGRKLCATFQHTETFEFQDEVGALLLSVCQKVGQGILCFLPSYKLLDKLKDRWIHTGLWRNLELVKTVIAEPQGGAKSDFDELLKIYYDAIKFKGEKDGALLIAVCRGKVSEGLDFCDENARAVITIGIPFPNVKDLQVELKRKYNDQHKTTRGLLPGSQWYEIQAYRALNQALGRCIRHRSDWGALILVDDRFRNNPNKYITGLSKWIRQQVQHHENFGSALESLHAFAERNQKGIDFSSQCSNEVFHVPLNSKEPSSASQQEATIHLSPDVPVKSEEQSFVPETHLTTTINSINPGPSNQPGGQKVDVESCSHNGIQRRKHMDSTPRRPANKTEKKSDRTNSDFMKEHCCFKPLTSTPLPVATNCVSTASSKQRKNVNSASELIGGVNQCQSSFTLEHKPSIPESHLETTNFSVKSTEAPVAEEHLDEQKLQIEPCSELPSVGGRPELSVLEISAEDEDESLYFTPELYDDAESEEQEMRPLDPDENQIECGKPTVADDLFVISTSKTLSEPKEMINDDGRNTSLHGTMLSDISKNSTVNIEKMTNGEEAEQVESQEVDTKKRKISLSRSRNKGVSPFLLDSTST
What is the function of this protein?
DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability.  Acts late in the 'Fanconi anemia' pathway of DNA repair, after FANCD2 ubiquitination.  Probably not involved in the repair of DNA double-strand breaks by homologous recombination.
What are the official names of this protein?
Fanconi anemia group J protein homolog, Protein FACJ, ATP-dependent RNA helicase BRIP1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CFI1_CAEEL
Sequence: MSVRIDEPQLFVSMSKEPTQETVNVGGHHDDSSSNCDERVDDQTEEQKSPPASPDLTANLNVFDLESRQKVVQRLLNSQLNLSNLRAPLNLPPIFQALQGPFSIQQQLLGLASGLTAISPGLDDYDEENTNQGEPEDLTLGGFRKETSVKSEEPSESGINASGPAWSYEEQFKQLYELSDDVKRKEWLDDWLNFMHRIGKPVTRIPIMAKQVLDLYELYRLVVQHGGLVEIINKKLWREITKGLNLPSSITSAAFTLRTQYQKYLYDYECEKEKLSNQSDLQQAIDGNRREAPGRRTAPSFPLPFQLPHAASAAATMLNNQLNGLGMRNDLLDDENTLSLQASGLFGTSYGAEQMAILEAHQRNLERAQRAVQQQVARQSLGLTACSNGNGGNIHNSGRESTSSNDSDIPAKRPKLENDVKTNGASSMRISTKHSDNSKTSMSVSMEINGITYQGVLFALDETVSES
What is the function of this protein?
Transcription factor (PubMed:11959845, PubMed:28056346).  Regulates neuronal subtype identity (PubMed:11959845, PubMed:28056346).  Involved in motor neuron fate determination and maintenance, acting as a transcriptional repressor to counteract gene activation by transcription factor unc-3 in a subset of motor neurons (PubMed:28056346).  Probably acts by binding to specific promoter elements (PubMed:28056346).  Promotes differentiation of URA sensory neurons and prevents them from expressing male-specific CEM neuronal features (PubMed:11959845).  Promotes differentiation of AVD and PVC interneurons and their glutamate receptor expression (PubMed:11959845).
What are the official names of this protein?
AT-rich interactive domain-containing protein cfi-1, ARID domain-containing protein CFI-1.
What are the subcellular locations of this protein?
Nucleus.