PharMolix/UniProtQA huggingface dataset:
Protein: SYI_STRA1
Sequence: MKLKETLNLGQTAFPMRAGLPNKEPQWQEAWDQADIYKKRQALNEGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFRAPYVPGWDTHGLPIEQVLAKKGVKRKEMDLAEYLEMCRDYALSQVDKQRDDFKRLGVSADWENPYITLTPDYEADQVRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGKGILDTDTYIVVWTTTPFTVTASRGLTVGPDMEYVVVVPVGSERKYLLAEVLVDSLAAKFGWENFEIVTHHTGKELNHIVTEHPWDTEVEELVILGDHVTTDSGTGIVHTAPGFGEDDYNVGIANGLDVVVTVDSRGLMMENAGPDFEGQFYDKVTPLVKEKLGDLLLASEVINHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKTNFQPEWGKKRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFAEYGSIVWWQRDAKDLLPAGYTHPGSPNGLFEKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSSLITSVAVNGHAPYKAVLSQGFVLDGKGEKMSKSLGNTILPSDVEKQFGAEILRLWVTSVDSSNDVRISMDILKQTSETYRKIRNTLRFLIANTSDFNPKQDAVAYENLGAVDRYMTIKFNQVVDTINKAYAAYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSPERRRMQTVFYDILVKLTKLLTPILPHTAEEIWSYLEHEEEEFVQLAEMPVAQTFSGQEEILEEWSAFMTLRTQAQKALEEARNAKVIGKSLEAHLTIYASQEVKTLLTALNSDIALLMIVSQLTIADEADKPADSVSFEGVAFTVEHAEGEVCERSRRIDPTTKMRSYGVAVCDASAAIIEQYYPEAVAQGFEA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_CHLCH
Sequence: MGIVINLLLLVLAALVAFVAGFFIGRYFLERIGTTKVLEAEERAVQIVQEAQKEANEYKELKVSEVNQEWKKKRREFEQDVLIKNNKFAQLQKQLQQREAQLKKQSQDVRDAERKLQDQRKEVEQLSDSVKLRATELERVIVEQNQRLESISNLQADEARQMLIDNMVTQAREEASNTIHRIHEEAEQQATRMAEKTLITAIQRISFEQTTENALSVVHIQSDELKGRIIGREGRNIKAFENATGVDIIVDDTPEVVILSCFDPLRRELAKLTLKKLLADGIIHPVAIEKAYADATKEIDDVVYSAGEEVAASLQLNDIPTEVIALLGKMKFHTVYGQNLLQHSREVAMLAGVMAAELKLDARMAKRAGLLHDIGLVLPESDEPHAITGMNFMKKFNESDQLLNAIGAHHGDMEKESPLADLVDAANTISLSRPGARGAVTADGNVKRLESLEEIAKGFPGVLKTYALQAGREIRVIVEGDNVSDSQADMLAHDIARKIESEAQYPGQIKVSIIREKRSVAYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: EX7L_CITBB
Sequence: MQLFKERRVLTVSALTALVRGLLEENFEQVWVEGEISNLACPQSGHCYFTLKDVGAQIRCVMFRGAFRSLKFTPRDGMRILTRGRLTLFEPRGEYQLVADYLEPQGIGGLQMAFIQLKEKLAKEGLFSELHKREIPKLPRRIGVVTSPTGAAIRDILTVLNRRFTNVELLISPVRVQGDGAAREIADAIDDLNRVGNLDVMIVGRGGGSLEDLWAFNEEVVARAIHRSKVPVISAVGHEIDFTIADFVADLRAATPSAAAEIVVASKKELTAEVEALTHRLHVSQQRRLERSRALVTALSRAITDPSRFLGHLAQRVDSLDARLTREAGLILDDASERIVTLTARLSRQTPALTLKRWEERLATLSLRLDHAMTRRLAVAAESIGLATGTLNAVSPLATLSRGYSITRKLPARSVVTSSRQLAPGDRVEVSFAAGSALCTVEQAHKDSDSLTAPPRSV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_METCA
Sequence: MEYSTRTDTLERLSTDCLIVGVFQKRKLAPTAEALDALFDGLLARLLKRDDVEGKAGDTLLVNHVPGGRIDRVLLVGLGKREELNVAAYRKSLAAAFKVLKESGAKHAVSALHEVEVGQRGADWKIRQAIELLESGLYRFQEMKGASAEDHPPRLSRLQFLLASDQDAAPVETGIREGQAIAHGMTLARNLGNLPGNVCTPAYLAEQALKLGKEYKKLKVSVLEESDMEELGMGALLSVARGSRQPAKLIVLEYRGAAGKAKPYVLIGKGLTFDAGGISLKPAANMDEMKYDMCGGAGVIGAIQAVAEMGLPLNVVGLVPASENLPDGNANKPGDIVRSMAGITIEILNTDAEGRLILCDALTYAKRFDPVAVIDVATLTGACIVALGRHPSGLMGNDDALCEQLTRAGETTWDRVWRMPIWDDYQEQLKSNFADVANIGGPDGGSITAACFLSRFAKDFKWAHLDIAGTAWKTGADKGATGRPVPLLVQYLIDRAA
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EP15R_MOUSE
Sequence: MAAPLVPLSQQIPGGNPLYESYYKQVDPAYTGRVGASEAALFLKKSGLSDIILGKIWDLADPEGKGFLDKQGFYVALRLVACAQSGHEVTLSSLSLTMPPPKFHDTSSPLMATQSSAETHWAVRVEEKAKFDGIFESLLPVNGLLSGDKVKPVLMNSKLPLDVLGRVWDLSDIDKDGHLDRDEFAVAMHLVYRALEKEPVPSILPPPLIPPSKRKKTVFAGAVPVLPASPPPKDSLRSTPSHGSVSSLNSTGSLSPKHSVKQPPVAWVVPVADKMRFDEIFLKTDLDLDGYVSGQEVKEIFMHSGLTQNLLAHIWALADTRQTGKLSKEQFALAMYFIQQKVSKGIDPPQVLSPDMVPPSERGTPIPDSSSTLASGEFTGVKELDDISQEIAQLQREKYSLEQDIREKEEAIRQKTSEVQELQNDLDRETSSLQELEAQKQDAQDRLDEMDQQKAKLRDMLSDVRQKCQDETQTISSLKTQIQSQESDLKSQEDDLNRAKSELNRLQQEETQLEQSIQAGRAQLETILRSLKCTQDDINQARSKLSQLQESHLEAHRSLEQYDQVPDGVSGTSLPDLATLNEGILLAERGGFGAMDDPFKNKALLFSNNSQELHPDPFQAEDPFKSDPFKGADPFKGDPFQSDPFSEQQTAATDPFGGDPFKESDPFHSSSSDDFFKKQTKNDPFTSDPFTKNPSLPSKLDPFESSDPFSSSSISSKGSDPFGTLDPFGSSSFSSAEGFADFSQMSKPPPSGPFSSSLGGTGFSDDPFKSKQDTPALPPKKPAPPRPKPPSGQSTPVSQLGSSDFPESPDPFQPLGADSGDPFQNKKGFGDPFSGKDPFAPSSSAKPPKTSSSGFADFTSFGNEEQQLAWAKRESEKAEQERLARLRRQEQEDLELAIALSKADMPA
What is the function of this protein?
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis.  Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2 (By similarity).
What are the official names of this protein?
Epidermal growth factor receptor substrate 15-like 1, Epidermal growth factor receptor pathway substrate 15-related sequence, Eps15-rs, Eps15-related protein, Eps15R.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Nucleus. Membrane, coated pit. Note=Localized to plasma membrane coated pits.
Protein: RSMG_XANCB
Sequence: MNDAALPPDVSAALANGLQAQSLDADFAAPLLRYLTLLVRWNKTYNLTAVRDPREMVTRHLLDSLAMQPYIVSGTLADLGTGPGLPGIPLAITRPQLQVTLVESNGKKARFMREALRHLALGNARVAEARAEAVDEPAAYDHLTARALDTLAGIIAVGGHLLRPGGSLLAMKGVYPREEIAALPAGWRVGDVHPLQVPGLEGERHLVVVHKD
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P53_MOUSE
Sequence: MTAMEESQSDISLELPLSQETFSGLWKLLPPEDILPSPHCMDDLLLPQDVEEFFEGPSEALRVSGAPAAQDPVTETPGPVAPAPATPWPLSSFVPSQKTYQGNYGFHLGFLQSGTAKSVMCTYSPPLNKLFCQLAKTCPVQLWVSATPPAGSRVRAMAIYKKSQHMTEVVRRCPHHERCSDGDGLAPPQHLIRVEGNLYPEYLEDRQTFRHSVVVPYEPPEAGSEYTTIHYKYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRDSFEVRVCACPGRDRRTEEENFRKKEVLCPELPPGSAKRALPTCTSASPPQKKKPLDGEYFTLKIRGRKRFEMFRELNEALELKDAHATEESGDSRAHSSYLKTKKGQSTSRHKKTMVKKVGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression (By similarity).  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis, but seems to have to effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-BMAL1-mediated transcriptional activation of PER2 (PubMed:24051492).
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: T22D1_HUMAN
Sequence: MHQPPESTAAAAAAADISARKMAHPAMFPRRGSGSGSASALNAAGTGVGSNATSSEDFPPPSLLQPPPPAASSTSGPQPPPPQSLNLLSQAQLQAQPLAPGGTQMKKKSGFQITSVTPAQISASISSNNSIAEDTESYDDLDESHTEDLSSSEILDVSLSRATDLGEPERSSSEETLNNFQEAETPGAVSPNQPHLPQPHLPHLPQQNVVINGNAHPHHLHHHHQIHHGHHLQHGHHHPSHVAVASASITGGPPSSPVSRKLSTTGSSDSITPVAPTSAVSSSGSPASVMTNMRAPSTTGGIGINSVTGTSTVNNVNITAVGSFNPNVTSSMLGNVNISTSNIPSAAGVSVGPGVTSGVNVNILSGMGNGTISSSAAVSSVPNAAAGMTGGSVSSQQQQPTVNTSRFRVVKLDSSSEPFKKGRWTCTEFYEKENAVPATEGVLINKVVETVKQNPIEVTSERESTSGSSVSSSVSTLSHYTESVGSGEMGAPTVVVQQQQQQQQQQQQQPALQGVTLQQMDFGSTGPQSIPAVSIPQSISQSQISQVQLQSQELSYQQKQGLQPVPLQATMSAATGIQPSPVNVVGVTSALGQQPSISSLAQPQLPYSQAAPPVQTPLPGAPPPQQLQYGQQQPMVSTQMAPGHVKSVTQNPASEYVQQQPILQTAMSSGQPSSAGVGAGTTVIPVAQPQGIQLPVQPTAVPAQPAGASVQPVGQAPAAVSAVPTGSQIANIGQQANIPTAVQQPSTQVPPSVIQQGAPPSSQVVPPAQTGIIHQGVQTSAPSLPQQLVIASQSSLLTVPPQPQGVEPVAQGIVSQQLPAVSSLPSASSISVTSQVSSTGPSGMPSAPTNLVPPQNIAQTPATQNGNLVQSVSQPPLIATNTNLPLAQQIPLSSTQFSAQSLAQAIGSQIEDARRAAEPSLVGLPQTISGDSGGMSAVSDGSSSSLAASASLFPLKVLPLTTPLVDGEDESSSGASVVAIDNKIEQAMDLVKSHLMYAVREEVEVLKEQIKELIEKNSQLEQENNLLKTLASPEQLAQFQAQLQTGSPPATTQPQGTTQPPAQPASQGSGPTA
What is the function of this protein?
Transcriptional repressor (PubMed:10488076).  Acts on the C-type natriuretic peptide (CNP) promoter (PubMed:9022669).
What are the official names of this protein?
TSC22 domain family protein 1, Cerebral protein 2, Regulatory protein TSC-22, TGFB-stimulated clone 22 homolog, Transforming growth factor beta-1-induced transcript 4 protein.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y432_TREPA
Sequence: MSGGVGVGKRLCCIALVMRAFWYLSAKGVSIAYVPVHRSGGSQDSSMSTAVGDTLLNAFFDEGMVVTAVPPGVHDGQTIAEIAACFEVMPDYALLVQFHSARLPGGESPTSRARGAWSSERFRAVWTLVDLHTQRACVYACVAPYRESIPVSECVDVVTRCIAEQAISYIRVGTSTDTAGVQL
What are the official names of this protein?
Uncharacterized protein TP_0432.
Protein: APT_ECO7I
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_MARSD
Sequence: MSLLVKVCGMTSKEDATMCEQLGVDFLGFIFHPSSPRNVDAAFARSVKTDGAKKVGVFVKQSATEVIETLKNGQLDFAQLHGGQNEEFCKAVGKERVIKVLWPQKYDSVKEFQADIDRFVPHCTYLLFDAGKSGGGHGIAMEFEVFKDVTIPVPWLLAGGLSAENLREALDTAQPNGVDLNSGVESEPGKKERNKLAAAFAAIGQ
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TM237_XENLA
Sequence: MGKKQVALPRALPPMPSTSIDEIPHSRPKKKKTKSNNNTPDDVLQNAGFTTSENNDPLSPERRKRKKKRFSIDAETSLTQNNPSIPVVLNGKDTDNQTTEEGATRKPRRRTKKTRLAEEEFPNELGVEDEDIIPDGHTKIPTQNPAFLASSLTSQPVGKLFVEKNRRFQAADRSEIIKTTEQMDVFLDVKPTWSSMDVSLTAHHIFRMVGLFCCGFLAGYAVWNIVVIYVLAGSQLTNLPNLLQTYKILAYPSQCFLYFLLVLSTVTAFDRIDLERAADALRGLLKLDPAAVASFFYFVALFLVLSQQMTSDRMNFYTPPTQNGSLWQTDTEGQILQPWIVINLVVAILVGLAWLFLSCRPDIDHSEEAMFIPEEEDYPDMEKGMKIQG
What is the function of this protein?
Component of the transition zone in primary cilia.  Required for ciliogenesis (By similarity).
What are the official names of this protein?
Transmembrane protein 237.
What is the protein family that this protein belongs to?
Belongs to the TMEM237 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes to the transition zone.
Protein: FSCH_DICDI
Sequence: MFIKFYFFIIFLILNFKNNYASPTLLDSVLSSTSSLSSPGSFFIETEFCPPPLLYRYSSDLEGDKGRGYKYVEFPNGTMSHCVHPCPSLYFSDGDWTTMMDMSLIVATISFFASIFLILTYSPLMNPSYNNRHTIGILSMSFGIFLIMFTDMYNLKKRFTLGCPSETRYAIQNDADCLITGLIFQFGCVSAVFFWTALSLDLYFQITNRNISRKYDLYYFIGVNLISLIFTFVPVISKSYGYGDFALGCWILDFNYALGCFWIPLSVCLIFSTVVVLMILYEVYKIYKASNQKTSLKGHIKPLLCLISNCFEFFYVFGYSLYLATKLTELHDNMDAYIKCLFLNSQNDPDSYTCPDHRLKLGPQFLFFLSLRLLGVSGIVFYGTNSKVRKIWKNSILINNRFIGKYFSFNSGTSTPVGSKNRSKTSSQLYDNSFGDSGILEEIREYDEKVKNGIIVTPGGDDDNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNENNENNTQEIELTNINTIDNV
What are the official names of this protein?
Frizzled/smoothened-like sans CRD protein H.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y2744_VIBC3
Sequence: MLCSIYKSPKKEGTYLYIPKRDDFSQVPDTLKQMFGKPIFVMLVNLEQRQLAQVNVEKVKQSMQEQGFFLQLPPPPENLLEQHKERKARQTP
What are the official names of this protein?
YcgL domain-containing protein VC0395_A1544/VC395_2072.
Protein: TREH_MYCTU
Sequence: MVLHAQPPDQSTETAREAKALAGATDGATATSADLHAPMALSSSSPLRNPFPPIADYAFLSDWETTCLISPAGSVEWLCVPRPDSPSVFGAILDRSAGHFRLGPYGVSVPSARRYLPGSLIMETTWQTHTGWLIVRDALVMGKWHDIERRSRTHRRTPMDWDAEHILLRTVRCVSGTVELMMSCEPAFDYHRLGATWEYSAEAYGEAIARANTEPDAHPTLRLTTNLRIGLEGREARARTRMKEGDDVFVALSWTKHPPPQTYDEAADKMWQTTECWRQWINIGNFPDHPWRAYLQRSALTLKGLTYSPTGALLAASTTSLPETPRGERNWDYRYAWIRDSTFALWGLYTLGLDREADDFFAFIADVSGANNNERHPLQVMYGVGGERSLVEAELHHLSGYDHARPVRIGNGAYNQRQHDIWGSILDSFYLHAKSREQVPENLWPVLKRQVEEAIKHWREPDRGIWEVRGEPQHFTSSKVMCWVALDRGAKLAERQGEKSYAQQWRAIADEIKADILEHGVDSRGVFTQRYGDEALDASLLLVVLTRFLPPDDPRVRNTVLAIADELTEDGLVLRYRVHETDDGLSGEEGTFTICSFWLVSALVEIGEVGRAKRLCERLLSFASPLLLYAEEIEPRSGRHLGNFPQAFTHLALINAVVHVIRAEEEADSSGMFQPANAPM
What is the function of this protein?
Catalyzes the hydrolysis of alpha,alpha-trehalose into two molecules of D-glucose.
What are the official names of this protein?
Trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 15 family.
Protein: O16G_CONAB
Sequence: VLIIAVLFLTACQLTTAETSSRGKQKHRALRSTDKNSRMTKRCTAPGGACYAAYTCCSNACNLNTKKCVLS
What are the official names of this protein?
Conotoxin AbVIG.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBD_THAPS
Sequence: MTIAIGQNQERGLFDLVDDWLKRDRFVFVGWSGILLFPTAYLAAGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSMGHSLLLLWGPEAQGDFTRWCQIGGLWAFIALHGAFGLIGFCLRQFEIARLVGIRPYNAIAFSGPIAVFVSVFLLYPLGQASWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFEDGDAANTFRAFTPTQSEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVAGLWTSSIGIVGLALNLRAYDFVSQELRAAEDPEFETFYTKNILLNEGIRSWMAAQDQPHENFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NU4M_HUMAN
Sequence: MLKLIVPTIMLLPLTWLSKKHMIWINTTTHSLIISIIPLLFFNQINNNLFSCSPTFSSDPLTTPLLMLTTWLLPLTIMASQRHLSSEPLSRKKLYLSMLISLQISLIMTFTATELIMFYIFFETTLIPTLAIITRWGNQPERLNAGTYFLFYTLVGSLPLLIALIYTHNTLGSLNILLLTLTAQELSNSWANNLMWLAYTMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRLTLILNPLTKHMAYPFLVLSLWGMIMTSSICLRQTDLKSLIAYSSISHMALVVTAILIQTPWSFTGAVILMIAHGLTSSLLFCLANSNYERTHSRIMILSQGLQTLLPLMAFWWLLASLANLALPPTINLLGELSVLVTTFSWSNITLLLTGLNMLVTALYSLYMFTTTQWGSLTHHINNMKPSFTRENTLMFMHLSPILLLSLNPDIITGFSS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:8644732, PubMed:8344246, PubMed:15250827).  Essential for the catalytic activity and assembly of complex I (PubMed:8644732, PubMed:8344246, PubMed:15250827).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GRAR_GLARU
Sequence: FGFLPIYRRPAS
What is the function of this protein?
Mast cell degranulating peptide.
What are the official names of this protein?
Granuliberin-R.
What are the subcellular locations of this protein?
Secreted.
Protein: LSPA_SHIFL
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVLLAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPB_METVO
Sequence: MKCNTKCDKNGYFGEFGGQYIPEVLKPAVEELKEAYKELKDDEDFQNELAYYLKHYAGRETPLYYAKNLTEKLGGAKIYLKREDLLHGGAHKTNNTIGQALLAKKMGKTRIIAETGAGQHGVGTSMAGALFGLETEIFMGRVDTERQQPNVARMKLLGAKVTPVDTGSKVLKDAVNEAMRNWTATFENTHYLLGTVMGPHPFPTMVRDFQSVIGKEVKKQIMEQEERLPDYLVACIGGGSNAMGLFHPFLSNNISTGNDDAKNVKMIGIEAAGKGLNTSLHGASITKGEKGVLHGMLSYFLQDEDGQIEEAYSISAGLDYPGIGPEHAYLHNLGRVQYASATDKQALKAFMELTRTEGIIPALESSHAIAYAIENAGNMDKDDIMVINLSGRGDKDLNTVINAVHKLGC
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: MGRA_STAAR
Sequence: MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVLTILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKSETIRPELSNASDKVASASSLSQDEVKELNRLLGKVIHAFDETKEK
What is the function of this protein?
Regulatory protein involved in autolytic activity, multidrug resistance and virulence.
What are the official names of this protein?
HTH-type transcriptional regulator MgrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_SALHS
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAVRGMVNAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: DBND1_BOVIN
Sequence: MEPSEGASPGGLVKEVDMPQAALSAPVPVTGTSGQSPMAEEELGIPIPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENVASDSHAGLHPLPRAGCLRSPSWTRTRAEQNREKQPFGDPERQPAIVDTILTVERPKED
What are the official names of this protein?
Dysbindin domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the dysbindin family.
Protein: CAP3_VIBCH
Sequence: MMSDVELVFKDESDCLVVIMGHVVTRLLSYRQLHHLTPESAGVLIGERRGQHLVVCDISEPGSGDIRQRCRVDRRGVHHQSRVNEAFERSAGTHLYLGEWHTHPEDRPFPSATDRHSWRRNIVSDESMLLLIVGRKDFWLGKKERELITVFKKIES
What is the function of this protein?
Protects E. coli against phage P1 and T2 infection.  When the 4 gene operon capV-dncV-cap2-cap3 is introduced in E. coli MG1655 there is about 100-fold protection against phages P1 and T2 (PubMed:31533127).  Protects E. coli against phage T2 infection.  When the CBASS operon (capV-dcnV-cap2-cap3) is introduced in E. coli MG1655 there is a more than 10(3) decrease in the efficiency of T2 plaque formation.  Protects 100-fold against phage T5, offers no protection against T7 (PubMed:32544385).
What are the official names of this protein?
CD-NTase-associated protein 3, Probable metalloprotease Cap3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67B family.
Protein: ARGC_STAAS
Sequence: MIKVGIVGGSGYGAIELIRLLQTHPHVTIAHIYSHSKVDEPLKLTFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSKTCIPPLVEKGIHVIDLSGAFRIKNREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLISEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSIIAGQDVSVIFTPHLVPMTRGILSTIYVKLSSEYTTESLHKLMTSYYANQPFVRIRDIGTFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQAIQNLNILYDFEVTTGLNQSPVYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLM_ENT38
Sequence: MGNAPQRPILITGGGRRIGLALAHHFLTLRQPVIVSYRNEYPSIEGLRQAGATCIQADFSTDEGILRFAETVKSNTRGLRAIIHNASAWQAEKPGTPLSETLACMMQIHVHAPYLLNHALEELLRGHGHAAGDIIHFTDYVVERGSDKHIAYAASKAALDNMTRSFARKLAPEVKVNAIAPSLILFNEEDDAEYRQKALNKSLMKIVPGEKEVIDLIDYLLTSCYVTGRSFGVDGGRPLN
What is the function of this protein?
Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin.  Also has lower activity with dihydrofolate.
What are the official names of this protein?
Dihydromonapterin reductase, H(2)-MPt reductase, Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FolM subfamily.