PharMolix/UniProtQA huggingface dataset:
Protein: PHOSP_HMPVC
Sequence: MSFPEGKDILFMGNEAAKLAEAFQKSLRKPSHKRSQSIIGEKVNTVSETLELPTISRPTKPTILSEPKLAWTDKGGAIKTEAKQTIKVMDPIEEEEFTEKRVLPSSDGKTPAEKKLKPSTNTKKKVSFTPNEPGKYTKLEKDALDLLSDNEEEDAESSILTFEERDTSSLSIEARLESIEEKLSMILGLLRTLNIATAGPTAARDGIRDAMIGIREELIADIIKEAKGKAAEMMEEEMNQRTKIGNGSVKLTEKAKELNKIVEDESTSGESEEEEELKDTQENNQEDDIYQLIM
What is the function of this protein?
Plays critical roles in regulating RNA replication and transcription through its interactions with multiple proteins (By similarity).  Tethers the RNA-directed RNA polymerase L to the nucleoprotein-RNA complex (PubMed:31698413).  Recruits the M2-1 protein, a processivity factor that is required for efficient transcription of viral RNA (By similarity).  Acts as a chaperone for neo-synthesized nucleoprotein by forming an N-P complex that preserves N in a monomeric and RNA-free state and prevents the association of nascent N with host cell RNAs (By similarity).  Recruits the host phosphatase PP1 to inclusion bodies to regulate viral transcription (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P.
What is the protein family that this protein belongs to?
Belongs to the pneumoviridae phosphoprotein P family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Localizes in cytoplasmic inclusion bodies.
Protein: PURA_STRPD
Sequence: MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLVKELAYLHDEGVTTDNLRISDRAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERLRINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVLSGLDTVKICVAYDLDGKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRVGELVGVRISTFSVGPGREQTNILESVWASI
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT5B_PLESK
Sequence: SGSCSLKTCWLQLADFRKVGDLLKEKYDSAAAMRISRKGKLELVNNRFNSPTPEDLVYVDPSPDYCLRNETTGSLGTQGRLCNKTSEGMDGCELMCCGRGYDQFKSVQVERCHCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-5b.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ATPB_WHEAT
Sequence: MRTNPTTSPPGASTIEEKSTGRIDQIIGPVLDVTFPPGKLPYIYNALVVQSRDTDDKQINVTCEVQQLLGNNRVRAVAMSATDGLMRGMEVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDSSATFPIHRSAPAFIELDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIEESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERIASTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLASKGIYPAVDPLDSTSTMLQPRIVGNEHYETAQRVKETLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVALAETIRGFQLILSGELDGLPEQAFYLVGNIDEASTKAITLEEENKSQK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: TRHO_STRSV
Sequence: MAKDIRVLLYYKYVPIENAEKFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVIVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERISVDINHVNPVVIGKDWFDGTPCERYVNCGNPECNRRILTSEENEDKYLRGCSHECRVHPRNRYVAENGLSQAEVVERLAAIGESLETLVAQ
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: HSP90_BRUPA
Sequence: MSEEMNGETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYQALTEPAELETGKELYIKITPNKADKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVASKHNDDDCYQWESSAGGSFIIRQVNDPELTRGTKITLYIKEDQTDYLEERRIKEIVKKHSQFIGYPIKLTVEKERDKEVSDDEAEEEKKDEDKEKKEGEIEDVGEDEEEDKKDKDKKKKKIKEKYHEDEELNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKTKNAIKLYVRRVFIMENCDELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFDEIAEDKDNFKKFYEQFSKNIKLGIHEDSTNRKKLSEFLRFYTSASSEEMTSLKDYVSRMKENQKQIYFITGESREAVASSAFVERVKRRGFEVIYMTDPIDEYCVQQLKEYDGKKLVSVTKEGLELPESEEEKKKFEEDKVKFENLCKVMKDILEKKVEKVAVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVIKALRERVEADKNDKTVKDLVVLLFETALLSSGFSLEDPQLHASRIYRMIKLGLDITEDEEEEAIASVSGEKDECVPNLVGAEEDASRMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 90.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LATA_LATHA
Sequence: SLVRMRREGEEDLTLEEKAELCSELELQQKYVDIGSNIIGDLSSLPIVGKIVGTIAAAAMAVTHVASGRLDIEQTLGGCSDVPFDQIKEILEERFNEIDRKLESHSAALEEITKLVEKSISAVEKTRKQMNKRFDEVMRSIQDAKVSPLVSKINNFARYFDTEKERIRGLKLSDYILKLEEPNGILLHFKESRTPRDDSLQAPLFSIIQERYAVPKSIDDELAFKVLYALLYGTQTYVSVMFFLLEQYSFLANHYYEKGDLEKYDEYFNSLNNVFLDFKSSLVGTGTSNNEGLLDRVLQVLVTVKNSEFLGLEKNGVNEMLNEKINLFNKIKVEIEGKQRMTLSETPENFAQISFDKDITTPIGDWRDGREVRYAVQYASETLFSKISHWSDPVGVREKACPTLRMPVDQTRRNILVFRKFDSSKPQLVGEITPYQSNFIDIDRDLYNTANNPDSAVGFKEFTKLNYDGANIRATFEQGRTVFHAAAKSGNSRIMIGLTFLVKSNELNQPDKKGYTPIHVAADSGNAGIVNLLIQRGVSINSKTYNFLQTPLHLAAQRGFVTTFQRLMESPEININERDKDGFTPLHYAVRGGERILEAFINQIRIDLNAKSNKGLTPFHLAIIKDDWPVASTLLGSKKVDVNAVDENNMTALHYAAILGYLETTKQLINLKEINADVVSSPGLLSALHYAILYKHDDVASFLLRSSNVNVNLKALGGITPLHLAVIQGRTQILSLMFDIGVNIEQQTDEKYTPLHLAAMSKYPELIQILLDQGSNFEAKTNSGATPLHLATFKGKSKAALILLNNEVNWRDTDENGQMPIHGAAMNGLLDVAQAIISIDATVLDIKDKNSDTPLNLAAQKSHIDVIKYFIDQGADINTRNKTGHAPLLAFSKKGNLDMVKYLFDKNANVYIADNDGINFFYYAVRNGHLNIVKYAMSEKDKFEWSNIDNNRRDECPKEECAISHFAVCDAVQFDKIEIVKYFVTTLGNFAICGPLHQAARYGHLDIEKYLVEEEDLNVDGSKPDTPLCYASENGHLAVVQYLVSNGAKVNHDCGNGMTAIDKAITKNHLQVVQFLAANGVDFRRKNKLGATPFLTAVSENAFDIAEYLIRENRQDIDINEQNVDKETALHLAVYYKNLQMIKLLVKYGIDMTIRNAYDKTALDIATDLKNSNIVEYLKTKSGKFRREYKSSYGEHSLLQTNKISSFIDGKNIEHDHPQFINADNESSQLFSDTASNIDVIGPLLLIDVLIRYFSKQGYISKESDSASDGITQAAALSITEKFEDVLNSLHNESAKEQVDLAEVHGKVYAALKSGRNSQIHPILCSSLKSISTLKPEDMEKLGSVIMNSHS
What is the function of this protein?
Presynaptic neurotoxin that causes massive release of neurotransmitters from vertebrate (but not invertebrate) nerve terminals and endocrine cells via a complex mechanism involving activation of receptor(s) and toxin insertion into the plasma membrane with subsequent pore formation.  Binds to neurexin-1-alpha (NRXN1) in a calcium dependent manner, adhesion G protein-coupled receptor L1 (ADGRL1, also termed latrophilin-1 and calcium-independent receptor of latrotoxin (CIRL)), and receptor-type tyrosine-protein phosphatase S (PTPRS), also termed PTP sigma.  NRXN1 and PTPRS are suggested to provide a platform for binding and subsequent pore formation events.  In contrast, binding to ADGRL1 does not involve oligomerization and channel formation, but direct downstream stimulation of the synaptic fusion machinery (By similarity).  Induces rapid muscle contracture and loss of twitch tension when added to the isolated and indirectly stimulated chick biventer cervicis nerve-muscle preparation (PubMed:22001442).
What are the official names of this protein?
Alpha-latrotoxin-Lh1a, Alpha-LTX-Lh1a, Alpha-latrotoxin, Alpha-LTX.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 01 (latrotoxin) family. 03 (alpha-latrotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a membrane channel in the prey.
Protein: MNMA_SHESM
Sequence: MTSIEPTHTGKKVIVGMSGGVDSSVSAYLLMQQGYQVEGLFMKNWEEDDNDEYCAAAEDLKDAQAVCDKLGIKLHTVNFAAEYWDNVFEYFLAEYKAGRTPNPDIMCNKEIKFKAFLDFADDILDADYIAMGHYVRRRDNADGTTQMLRGVDNNKDQSYFLYTLSHEQVARSLFPVGELEKHEVREIAKKMGLITHDKKDSTGICFIGERKFTEFLGNYLPAQPGNIETAEGEVIGKHQGLMYHTLGQRKGLGIGGMKNSNDDPWYVVDKDLKRNVLVVGQGGHHPRLMSNGMLVNQLHWVDRKGPAEGSQIVVKTRYRQQDIPCTLTYLDDNTLKVVFDEPVAAVTPGQSAVFYDGEVCLGGGIIDQLIRG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_RHORU
Sequence: MEIRAAEISAILKEQIANFGTEAESAEVGQVLSVGDGIARVYGLDNVQAGEMVEFANGVKGMALNLESDNVGIVIFGEDRGIKEGDVVKRTQTIVDVPVGKGLLGRVVDGLGNPIDGKGDLVDVERKRAEVKAPGIIPRKSVHEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAVILDTILNQKAVNDKAKDDSEKLFCVYVAVGQKRSTVAQVVKVLADHGALDYTIVVAATASEPAPLQFLAPYTGCTMGEFFRDNGMHAVIFYDDLTKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLNDDNGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFKGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYREMAAFAQFASDLDPATQKLLARGARLTELLKQAQYSPLAVEEQVCVIYAGTRGYLDKLKTTDVVRYEASLLGALRTSGADLLESIRTGKALSKEIEQKLVKFLDDFGKKFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: P19_PLV
Sequence: MERAIQGSDAREQAYSERWDGGCGGTITPFKLPDESPSLIEWRLHNSEESEDKDNPLGFKESWSFGKVVFKRYLRYDGTEASLHRALGSWERDTVNNAASRFLGFGQIGCTYCIRFRGSCLTISGGSRTLQRLIEMAIRTKRTMLQLTPCEVEGNVSRGSPEGTEAFKEESE
What is the function of this protein?
Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs).  Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).
What are the official names of this protein?
RNA silencing suppressor p19, 19 kDa symptom severity modulator.
What is the protein family that this protein belongs to?
Belongs to the tombusvirus protein p19 family.
Protein: LYC1_YARLI
Sequence: MSLREITSPDEIRDTRSFSHLEWGAFLSIDDYNHREEIVLGHTPMCKNRLKSWGLYIEDGTRVAACETLERPALVQCKDGKIKSTSTFSIGAVFTPKEHRGKGYASVMMKQMASGIPFKPTLTDADIIKATGVSDVDQTLRVTPLWSDVGTFYEKFGWIGTTDLQYVFEVDGSASQNGVNGTPNGTNGTNGVNGHTNGTNGHSSAVKYLSEEDVYRLADVEASSFASDFEKFPFKGSYKCGIVPDRTVYEWHLARAKFLAKFAKVPEPKVFGAQIGDSWMAWHHMYNARELVILRAKLAKAEDLVELIAAAKNHLCKDGFSDQINKIILWEQEREWNHIVDGLSYDAIDQAIEKSQGKREHRGSSIPAVMFVEYKLQKDAMEFVDHGKLTWC
What is the function of this protein?
Lysine N-6-acetyl transferase (LAT) that catalyzes the first step of the lysine degradation pathway.
What are the official names of this protein?
Lysine acetyltransferase, LAT, Lysine N(6)-acetyltransferase.
Protein: DEFI6_DANRE
Sequence: MDLRSELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLKIPHEAAALEEHFRDDDDGPVSSQGYMPYLNKYILDKVVEGTFVKENVDELCWTLTAKKNYRPEGKSILPAKDAFRLWCLFIFLSEDRYPLVMIPDEVEYLLKKFCMAMSVELNYVELEDFISQDSVQQNGFTVWTFLEMMNSGKLTRGIAKETVSMAIEEVYREIVGDVLKEGYLWKKGQLRRNWTERWFTLRPSTLLYFTSEDRKDHKGNIQLDGNCCVEVLPDRDGKRCMFCLKTLTKTYELSASDTKQRQEWTTAIQTAIRLYVEGKTSLHKDLKLKRRDQREQREKRREAKEQELQRLRALQEERERKMAELELLKEAQRQAQAMLEQDEQRRRQQHEQLHQALEIQLKEAEEARASMQAEMALKEAEAEKQRTRIRELEAMQQRLEDALQQEIKARQDEEAFRYAQARLLAEEEEKMKALMGLREEQEEYIQRAQREKQELRQEMESKSRALEEAQRQLEETRANRYRVDQDVVAAQRKLRQASTNVKHWNVQMNRLMHPIGPGEKRSSGGSFSSFRIPSQKDPALRQKQKSEEQDEESKENMESRGGCEADRRLSTNGQMEIP
What are the official names of this protein?
Differentially expressed in FDCP 6 homolog.
Protein: VE4_HPV05
Sequence: MTDPNSKAPRLQGRQEDKQTQTPPPRPPPPPQPPLTPRPDSSPHQNSHNKPKPEEEGTDGGPPASQGDRKRSKGDQGPDTGPGLGPGRGPSPKPTPLGPPPGPGPRRSPRLGPLQADRDPEEGPQPPAEGEVEGHPGGDQGHPPPPPPAPHNGHSGHEPKVQQPEGPEGREGHEEGAVGGEGGDEEGHPPPPPPPTNGHEGGLLSSVASLLVKWEGHFDQLVQSIQDDLEDYWKKLATPQ
What is the function of this protein?
Contributes to multiple aspects of the viral life cycle including viral genome amplification, suppression of suprabasal cell differentiation and egress of newly formed virions.  Induces host cell cycle arrest at the G2 phase by associating with and preventing the nuclear entry of host CDK1/cyclin B1 complexes.  Inhibits cellular DNA replication by preventing loading of host replication licensing proteins MCM2 and MCM7 onto chromatin.  Within the cytoplasm, associates with host kinase SRPK1, a splicing factor regulator, and inhibits its activity.  Therefore, E4 favors expression of late viral transcripts by inhibiting SRPK1-mediated phosphorylation of host serine-arginine (SR) proteins that have critical roles in mRNA metabolism.  Late in the infectious cycle, E4 also acts to diminish the integrity of the keratinocyte by disrupting the keratin cytoskeleton and inducing apoptosis through alteration of mitochondrial function to facilitate egress of the newly formed virions.
What are the official names of this protein?
Protein E4.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E4 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MOAE_STAES
Sequence: MKQFEIVTQPIETEQYRDFTINERQGAVVVFTGHVREWTKGIRTQHLEYEAYIPMAEKKLAQIGKEIEEKWPGTITTIVHRIGPLQISDIAVLIAVSSPHRKAAYAANEYAIERIKEIVPIWKKEIWEDGAEWQGHQKGTYNEAKKGKAR
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, MPT synthase subunit 2, Molybdenum cofactor biosynthesis protein E, Molybdopterin-converting factor large subunit, Molybdopterin-converting factor subunit 2.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.
Protein: BM8E_BOMMX
Sequence: MKCFAQIVVLLLVIAFSHGAVITGVCDRDAQCGSGTCCAASAFSRNIRFCVPLGNNGEECHPASHKVPYNGKRLSSLCPCNTGLTCPKSGEKFQCS
What is the function of this protein?
Potent agonist for both PKR1/PROKR1 and PKR2/PROKR2, and inducer of a potent and long-lasting hyperalgesia.  Also potentiates capsaicin-induced TRPV1 current, when tested on DRG neurons.  At subnanomolar concentrations, this protein both induces potent chemotaxis of macrophages and stimulates LPS-induced production of the pro-inflammatory cytokines IL-1 and IL-12.  In vivo, potently stimulates the contraction of the guinea-pig gastrointestinal (GI) smooth muscle (nanomolar concentration).
What are the official names of this protein?
Prokineticin Bm8-e.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CFMN1_GIBZE
Sequence: MKLSVFTSVLLAGLVAAQQEKLPKCAQPCVDQYTTGGGVAGCGQLDIKCICSNKNFLSGIACCLEKECDAQGKETAVKYAKQICATAGVTDLPDDVTCDKSAASSGTASGTATGATTPTSSDSTNTASATGGSSTVEPNAGAREGAAGFIGVGMAMLLAL
What is the function of this protein?
Suppresses host programmed cell death during infection by binding to Z. mays WAK17 isoform 2 and Z. mays LRR5, to prevent activation of Z. mays WAK17 isoform 1 and the downstream hypersensitive response.
What are the official names of this protein?
Effector CFEMN1.
What is the protein family that this protein belongs to?
Belongs to the RBT5 family.
Protein: ATPA_STAA1
Sequence: MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGLNDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEELIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGALDYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNVISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYRELESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPVVDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHBG_SHIFL
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRIDRQPLSNAGDLPANLRSSQGFSSAFYGEEISEALFLQVLDDASHRGDPSLEVMCHPAFIDNTIRQSAYCFPRLTELEVLTSASLKYAIAERGYRLGSYLDV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_BURM1
Sequence: MNTETKPLPAWLDKVRWDDNGLVPVIAQEASTNDVLMFAWMNREALAKTIETQRAVYYSRSRKRLWFKGEESGHVQHVHEVRLDCDEDVVLLKVEQVSGIACHTGRHSCFFQKFEGTVDAGDWVAVDPVLKDPEHIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRK_LACLA
Sequence: MPKLQEMMTIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISSWDKVAKTCTILYRIGDETSGTYEISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGIGVPPLYELAKQLEEKNCQMTILLGFASEKVKILEKEFAELKNVSLKIATDDGSYGTKGHVGMLMEEIDFEVDALYTCGAPAMLKAVAKKYEQLERLYISMESRMACGIGACYACVEHDKEDENHALKVCEDGPVFLGKQLLL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: QUEA_ALTMD
Sequence: MKLSDFSFVLPENLIAKYPTQQRTASRLLHLDGKNGKVEHTMFADMLKFVEPGDLLVFNNTRVIPARLLGKKETGGQVEVLIERITSDTTALAHVRASKAPKPGTKLILEEKVNVTVTGRDDALFILQFDHDETVLTLLEAHGHMPLPPYIDRPDENSDKERYQTVYNEKPGAVAAPTAGLHFDDSILNALKEKGVNLAFVTLHVGAGTFQPVRVDNIQEHKMHAEFAEVPQDVVDAVLNTKANGKRVIAVGTTSVRSLESAAKASAERGDEQIIAPFNEDTEIFIYPGFEFKVVDAMFTNFHLPESTLMMLISAFAGKENVMNAYQEAIAKEYRFFSYGDAMFIERA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRA6_SHIFL
Sequence: MINVAILSAIRRWHFRDGASIREIARRSGLSRNTVRKYLQSKVVEPQYPARDSVGKLSPFEPKLRQWLSTEHKKTKKLRRNLRSMYRDLVALGFTGSYDRVCAFARQWKDSEQFKAQTSGKGCFIPLRFACGEAFQFDWSEDFARIAGKQVKLQIAQFKLAHSRAFVLRAYYQQKHEMLFDAHWHAFQIFGGIPKRGIYDNMKTAVDSVGRGKERRVNQRFTAMVSHYLFDAQFCNPASGWEKGQIEKNVQDSRQRLWQGAPDFQSLADLNVWLEHRCKALWSELRHPELDQTVQEAFADEQGELMALPNAFDAFVEQTKRVTSTCLVHHEGNRYSVPASYANRAISLRIYADKLVMAAEGQHIAEHPRLFGSGHARRGHTQYDWHHYLSVLQKKPGALRNGAPFAELPPAFKKLQSILLQRPGGDRDMVEILALVLHHDEGAVLSAVELALECGKPSKEHVLNLLGRLTEEPPPKPIPIPKGLRLTLEPQANVNRYDSLRRAHDAA
What is the function of this protein?
Required for the transposition of the insertion element.
What are the official names of this protein?
Transposase for insertion sequences IS1326/IS1353.
What is the protein family that this protein belongs to?
Belongs to the transposase IS21/IS408/IS1162 family.
Protein: UGE2_ARATH
Sequence: MAKSVLVTGGAGYIGSHTVLQLLEGGYSAVVVDNYDNSSAASLQRVKKLAGENGNRLSFHQVDLRDRPALEKIFSETKFDAVIHFAGLKAVGESVEKPLLYYNNNIVGTVTLLEVMAQYGCKNLVFSSSATVYGWPKEVPCTEESPISATNPYGRTKLFIEEICRDVHRSDSEWKIILLRYFNPVGAHPSGYIGEDPLGVPNNLMPYVQQVAVGRRPHLTVFGTDYKTKDGTGVRDYIHVMDLADGHIAALRKLDDLKISCEVYNLGTGNGTSVLEMVAAFEKASGKKIPLVMAGRRPGDAEVVYASTEKAERELNWKAKNGIEEMCRDLWNWASNNPYGYNSSSNGSSS
What is the function of this protein?
Catalyzes the interconversion between UDP-glucose and UDP-galactose (Ref. 6, PubMed:16644739, PubMed:19754426).  Cooperates with UGE3 in pollen development and with UGE4 in cell wall carbohydrate biosynthesis and growth (PubMed:17496119).
What are the official names of this protein?
UDP-glucose 4-epimerase 2, AtUGE2, UDP-galactose 4-epimerase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1276_XYLFT
Sequence: MSMPTMTLVNQLLIALPSMPDPHFARGVALICQHDSNGAMGVVLNRPSEYTLGEVLFQMGIETASETLREQVVLAGGPVHPDRGFVIYDSEHVWGPSLLIGDGLYLTTSRDVLAAMAEGSGPSRALVALGCAGWAAGQLELELVENNWLMVPADASLLFDTALEQRWQRAAGRIGVDLFRLTDYTGHA
What are the official names of this protein?
UPF0301 protein PD_1276.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: HOSM_SCHPO
Sequence: MSVSEANGTETIKPPMNGNPYGPNPSDFLSRVNNFSIIESTLREGEQFANAFFDTEKKIQIAKALDNFGVDYIELTSPVASEQSRQDCEAICKLGLKCKILTHIRCHMDDARVAVETGVDGVDVVIGTSQYLRKYSHGKDMTYIIDSATEVINFVKSKGIEVRFSSEDSFRSDLVDLLSLYKAVDKIGVNRVGIADTVGCATPRQVYDLIRTLRGVVSCDIECHFHNDTGMAIANAYCALEAGATHIDTSILGIGERNGITPLGALLARMYVTDREYITHKYKLNQLRELENLVADAVEVQIPFNNYITGMCAFTHKAGIHAKAILANPSTYEILKPEDFGMSRYVHVGSRLTGWNAIKSRAEQLNLHLTDAQAKELTVRIKKLADVRTLAMDDVDRVLREYHADLSDADRITKEASA
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, mitochondrial, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.