PharMolix/UniProtQA huggingface dataset:
Protein: RS14_PROM3
Sequence: MAKKSMIARDVKRKKIVERYAAKRAALMAAFDAAKDPMQRLEIHRKIQALPRNSAPTRIRNRCWATGKPRGVYRDFGLCRNQLRERAHKGELPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: DNAE2_GLUOX
Sequence: MAMYCEPRSEWWTRLPAPGGHRAWIACSSALSRSAVLAGTPARLPVSTSAFLTHSFSVCAEQPILLAIDTIAVQRDGCSPSCSRTRRTARERTSGENFFTGLLIRPSSQVNRSPLIPGRFNPTETERTGESAQETLTRLVQAALPRRYPAGAPPEVETQIAHELRLIGSLSYAPYFLTVNTIVRHARSLGIVCQGRGSAANSAVCYVLGITSIDPVRSGLLFERFISTERQEPPDIDVDFESDRREEVIQWIYRHYGRHRAALCATVQRYQPKGALREVGKVLGLPEDLTGQLSKHIASSLADPDLCKARAADLGLNLKDRRLSLTFHLARLLLGFPRQLGTHPGGFVLTEDRLDELVPLMPTAMDGRQIIVWDKDDIDVLRFMKVDVLGLGMLGCLRRGFELLHTVYQTRMDLAAIPAEDPQTYRMVQKADTLGTFQIESRAQMSMLPRMKPATFYDLVIQVAIVRPGPIQGDMVHPYLRRREKLEPVTYPSETLRGILGKTLGVPLFQEQAMQVAIHCAGFTPGEADQLRRAMATFKMTGGVSPFRDKLVNGMLANGYEQEFAEQTFAQLEGFGSYGFPESHAASFALIAYASAWMKCHYPDVFCAALLNSQPMGFYAPSQIVQDAQRHGVEVRPICINASRWDCTLERGRNGRHAAVRLGFRMVKGLANGHGAALIAARMPDYESIDDVWRRADVPVAALKCLAEADAFRVFGQMRRAALWSIKGLADTALPLFEAADRGRNFPLPEVIEPEITLPMMSERASVHEDYRATGLSLNGHPVAFLREGLRKEGIVRCGDLPYLRDGRRIQLTGLVLMRQRPGTANGTMFVTIEDETGTANLIVWKDVQEKYRRPLLASRLLACKGRLQKEGDVIHVVVLSLEDRTPLLQGSEPLKARDFR
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase (By similarity).
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THF1_PARMW
Sequence: MAERHTIADSKRAFHQAFPHVIAPLYRRIADELLVELHLLSHQATFQANSLFAVGLKTVFERFTQGYRPMEHPAALLSALCSSNGFDDEQLKQAAQHCLQDAEGHSDDAFQSWLKEQSLSDGAHYSRLMAVGLLALLEASSDESDASSLRQRAVKLSVDLGLPAERVEKDLTVFSSNSERMEQAVELMQETLAADRRKKEKRLAEAAESTAG
What is the function of this protein?
May be involved in photosynthetic membrane biogenesis.
What are the official names of this protein?
Protein Thf1.
What is the protein family that this protein belongs to?
Belongs to the THF1 family.
Protein: RPOA_SALCH
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLEDWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: THIG_GEOSL
Sequence: MSNAADKLVIAGREFSSRLMVGTGKYASNEQMIKALEVSGAEIITVAVRRVNLADRGKGCLLDFIDPKKYTLLPNTAGCYTADDAVRTCRLAREAGMSDLVKLEVLGDEKTLFPDNEELLKAAKILVKEGFTVLPYTSDDPIVCKKLEDIGCAAVMPLGAPIGSGLGIRNPYNILIIKETVKVPVIVDAGVGTASDAAIAMELGIDGVLMNTGIAGARDPIAMAEAMNMAVRAGRLAYLAGRIPKKLYATASSPIEGMIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_BACAH
Sequence: MSKEIAKKRIEELRDLLNTFNYQYHVLDNPSVSDAEYDRNMQELIKLEAENPEFMSEDSPSVRVGGTVLDIFEKVTHKSPMLSLGNAFNEGDLRDFDRRVRQGIDDANVRYICELKIDGLAVSLHYEKGRFIQGATRGDGVTGEDITQNLKTIKAIPLRLNEEVTLEARGEAYMPKRSFVKLNEEKEQNGEDVFANPRNAAAGSIRQLDPKIAAKRNLSMFVYGLANVEEKTIPSHSESLDFLGELGFKTNPNRRTCETIEEVIAYVEEWQEKRPHLDYEIDGIVIKVDDVALQESLGTTAKSPRWAIAYKFPAEEVVTRLTGIELSVGRTGVVTPTAELEPVRVAGTIVRRASLHNEDLIREKDIRIGDYVVVKKAGDIIPEVVNVIFDKRTGEEEEYHMPTHCPACESELVRLEEEVALRCINPTCPAQIREGLIHFVSRNAMNIDGLGERVITQLFDADYIRTFADLYSLTKEQLLQLERFGEKSATNLVQAIENSKENSLERLLFGLGIRHVGAKAARTFAEHFETMDALVKATEEELKAINEIGEKMAQSVVAYFDNEDVLELLQQFKEYGVNMTYKGIKIADLQNVESYFAGKTVVLTGKLEVMGRSEAKKKIEALGGKVTGSVSKSTDLVVAGEAAGSKLAQAEKHNVEVWNEERFLQELNK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DNS2A_PIG
Sequence: MATLSPLLLAALLWVPVGTLTCYGDSGQPVDWFVVYKLPAHSSPGDVAQSGLRYKYLDEESGGWRDGAGSINSSTGALGRSLLPLYRNTSQLAFLLYNDQPPKYRGSQHSSNRGHTKGVLLLDQEGGFWLIHSVPNFPPPSSSAAYSWPPSARTYGQTLICVSFPLTQFLNISRQLTYTYPMVYDYKLEGDFARKFPYLEEVVKGHHVLQEPWNSSVTLTSKAGASFQSFAKCGNFGDDLYSGWLAEALGSNLQVQFWQRSAGILPSNCSGVQHVLDVTQIAFPGPAGPNFNATEDHSKWCVAPERPWTCVGDMNRNKREEHRGGGTLCAQLPALWKAFKPLVKAWEPCEKENRAFSPRSPAKD
What is the function of this protein?
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA.  Plays a major role in the clearance of nucleic acids generated through apoptosis, hence preventing autoinflammation.  Necessary for proper fetal development and for definitive erythropoiesis in fetal liver and bone marrow, where it degrades nuclear DNA expelled from erythroid precursor cells.
What are the official names of this protein?
Deoxyribonuclease-2-alpha, Acid DNase, Deoxyribonuclease II alpha, DNase II alpha, Lysosomal DNase II.
What is the protein family that this protein belongs to?
Belongs to the DNase II family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RL9_AGRVS
Sequence: MQVILLERIAKLGQMGEVVKVRDGFARNYLLPTGKALRANAANKARFDAERSTLEARNLERKSEAQTVADVLNGKSFIVVRSAGETGQLYGSVAARDIIEALAAEGFTVSRNQVELNNPIKTIGLHNVTMHLHAEVEIAIEINVARSAEEAERQAKGESLTSADAIYGVDEDALRPEDFFDPDADRDGDDE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: BIOD_GEOKA
Sequence: MGQAIFMTGTGTEIGKTVVTSIVALALERLGMSVSVLKPVQTGLAEDGVSFAEQYWYERVAKLSASEGMYYMEPAMSPHLAAKLTGTSIEPERVAERLEWLKQRYDVVLVEGAGGLAVPWCERDGRFYMTSDFLRDYQLPAILVSLSSLGAIHHAVTTAAYADAQGIRLLGLMFNQFQEQEIIHQNNVETIAALLRLPVLAVVPLLPAVSRRELETLAQHWIEQGKAKQLLEVLGVGV
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL1B_ACIFR
Sequence: MAVKTYNAGVKDYRNTYWEPDYSVKDTDILAVFKITPQAGVDREEAPAAVAAESSTGTWTTVWTDLLTDLDYYKGRAYRIEDVPGDDTCFYAFIAYPIDLFEEGSVVNVFTSLVGNVFGFKAVRALRLEDVRFPIAYVKTCGGPPHGIQVERDIMNKYGRPLLGCTIKPKLGLSAKNYGRACYEGLRGGLDFTKDDENVNSQPFMRWRQRFDFVMEAIQKAEAETGERKGHYLNVTAPTPEEMYKRAEYAKEIGAPIIMHDYITGGFCANTGLANWCRDNGMLLHIHRAMHRVLDRNPHHGIHFRVLTKILRLSGGDHLHSGTVVGKLEGDREATLGWIDIMRDRFIKEDRSRGIFFDQDWGSMPGVMPVASGGIHVWHMPALVTIFGDDSVLQFGGGTLGHPWGNAKGAAANRVALEACVEARNRGVAIEKEGKAVLTEAAKHSPELKIAMETWKEIKSEFDTVDKLDVAHK
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain 2, RuBisCO large subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: NUDI_SALAR
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVRPEEFALYDLNVATRHTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: MENA_MYCTU
Sequence: MASFAQWVSGARPRTLPNAIAPVVAGTGAAAWLHAAVWWKALLALAVAVALVIGVNYANDYSDGIRGTDDDRVGPVRLVGSRLATPRSVLTAAMTSLALGALAGLVLALLSAPWLIAVGAICIAGAWLYTGGSKPYGYAGFGELAVFVFFGPVAVLGTQYTQALRVDWVGLAQAVATGALSCSVLVANNLRDIPTDARADKITLAVRLGDARTRMLYQGLLAVAGVLTFVLMLATPWCVVGLVAAPLALRAAGPVRSGRGGRELIPVLRDTGLAMLVWALAVAGALAFGQLS
What is the function of this protein?
Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).  Can use a variety of allylic isoprenyl diphosphates as substrates but has a requirement for at least three isoprene units.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoate octaprenyltransferase, DHNA-octaprenyltransferase, Isoprenyl diphosphate:1,4-dihydroxy-2-naphthoate isoprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MenA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LOLD_BARQU
Sequence: MAAILELVEIERHFFESHKPLIILDKANFILNRGELVALVAPSGAGKSTLLHIAGLLEKPTAGDVILRGVSCAKRSDNERTAIRRNDIGFVYQFHHLLPEFTALENIIIPQMIAGFKKSIAEDRALKLLTYLRVSHRANHRPSELSGGEQQRVAIARAVANGPSVLLADEPTGNLDPVTSAYVFQALSALVRQSGLSALIATHNYGLAKQMHRRITLKEKKIVELP
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SDHD_SALTY
Sequence: MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPYLAKAFPQTAAAGGMIESDVVAIPAMQKRLEKEYGQTINGEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICASVAYQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: AAEB_ECO55
Sequence: MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLAGMLHKYQHALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXS_STAA8
Sequence: MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVMALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAMKGLDINQLSLEERMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: UVRC_BURM7
Sequence: MTSPDAPESRFEPKPILAQLPHLPGVYRYYDVQDAVLYVGKARDLKKRVSSYFTKTQLSPRIAMMITRIARIETTVTRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTGHRFPRMAYYRGAVDKKNQYFGPFPSAWAVRESIQILQRVFQLRTCEDSVFNNRTRPCLLHQIGRCSAPCVGAIGEEDYARDVDNASRFLLGRQGEVMGELERKMHAFAAELKFEQAAAVRNQMSSLAKVLHQQAIDVGGDSDVDILAVVAQGGRVCVNLAMVRGGRHLGDKAYFPAHVETALALAGDIEALAGEGAGDGVQAAAQPAQAPLATDADATDAAATEAKTVTAAAAARAGARTAQAAGARAAASAEGDVERRAEGETHARADAREAAALPDGAAAAQEADADVDAAPLETEVLEAFIAQHYLGNRVPPVLVVSHAPANRELIDLLVEQAGHKVAVVRQPQGQKRAWLTMAEQNARLALARLLSEQGSQQARTRSLADVLGYESDDLAQLRIECFDISHTMGEATQASCVVYHHHRMQSSEYRRYNIAGITPGDDYAAMRQVLTRRYEKMVEEAAAEASADEAAGIDGNAVHAAASAGRLPNVVLIDGGRGQVEIARQVFSELGLDISMLVGVAKGEGRKVGLETLIFADGRAPLELGKESAALMLVAQIRDEAHRFAITGMRAKRAKTRQTSRLEELEGVGAKRRQRLLARFGGLRGVVAASVDELASVEGISRALAEQIYRQLH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4855_PSEPG
Sequence: MSEPDVKSHKIEFPCDDYPIKVIGDTVVGFKDTVIEILSKHAKVDLSTLAERQSKEGKYTTVQLHIVAESENQLHDINSALRATGIVKMVL
What are the official names of this protein?
UPF0250 protein PputGB1_4855.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: GLYC_ALLVP
Sequence: MGQVVTFLQSLPEVINEAINIALIAISIICILKGLVNFWKCGVVQLAIFLCLAGRKCDGLMIDRRHELSHVELNLTRMFDNLPQSCSKNNTHHYYKGPKGTTWGIELTLTNTSLDSYANMSRIRSLAFGNITNCDKTGEAGHTLKWLLNELHFNVLHVTRHVGARCRVSEGAGLLIQYNLTIGDHGGEVGRHLIASLAQIIGDNKAAWVGKCDSHCTMDGKCNYTNCEGFTHYNYLIIQNTTWENHCSYSPMSTIRMALNKVAYSSVSRQLLGFFTWDISDSSGAHVPGGYCLEQWAIVWAGIKCFDNAVMAKCNKDHNVEFCDTMRLFDFNQNAIKTLQLNVENSVNLLKRSINGLISDSLVIRNSLKQLAKIPYCNYTKFWYVNDTITGKHSLPQCWLMRNGSYLNETHFKNEWLWESQNLYNEMLLKEYEDRQGKTPIALTDICFWSLVFFTSTVFLQLVGIPTHRHLVGEGCPKPHRITSNSLCACGYYKIPKRPTRWVRKGK
What is the function of this protein?
Forms the virion spikes together with glycoprotein G1.  The glycoprotein spike trimers are connected to the underlying matrix.  Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm.  Membrane fusion is mediated by irreversible conformational changes induced by acidification.
What are the official names of this protein?
Pre-glycoprotein polyprotein GP complex, Pre-GP-C.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae GPC protein family.
What are the subcellular locations of this protein?
[Glycoprotein G1]: Virion membrane; Peripheral membrane protein. Host endoplasmic reticulum membrane; Peripheral membrane protein. Host Golgi apparatus membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Glycoprotein G2]: Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Host Golgi apparatus membrane; Single-pass membrane protein. Host cell membrane; Single-pass membrane protein. Note=Binding to the stable signal peptide masks endogenous ER localization signals in the cytoplasmic domain of G2 to ensure that only the fully assembled, tripartite GP complex is transported for virion assembly. SUBCELLULAR LOCATION: [Stable signal peptide]: Virion membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Host cell membrane; Multi-pass membrane protein.
Protein: PROCJ_OLEEU
Sequence: MSWQAYVDEHLMCEIEGHHLASAAILGHDGTVWAQSADFPQFKPEEITGIMKDFDEPGHLAPTGMFVATAKYMVIQGEPGAVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLMKQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-5, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: GCST_THEMA
Sequence: MKRTPLFEKHVELGAKMVDFAGWEMPLYYTSIFEEVMAVRKSVGMFDVSHMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKVSPDEALMVVNAANIEKDFNWIKSHSKNFDVEVSNISDTTALIAFQGPKAQETLQELVEDGLEEIAYYSFRKSIVAGVETLVSRTGYTGEDGFELMLEAKNAPKVWDALMNLLRKIDGRPAGLGARDVCRLEATYLLYGQDMDENTNPFEVGLSWVVKLNKDFVGKEALLKAKEKVERKLVALELSGKRIARKGYEVLKNGERVGEITSGNFSPTLGKSIALALVSKSVKIGDQLGVVFPGGKLVEALVVKKPFYRGSVRREV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: R1A10_SOLDE
Sequence: MYFNNELSDLKDHLLRKLQYYTYSDVVRDRINFILWEFKFLDCFLYLKSFPFASECGMLHVSQKMIEIWKSQWNKLIYICMYDEEGSPWDAVVYWKELISQTKQEFRAQYSFPKSPLAANEVIDDDDDDNTHSPEFVMEVIGFFVGNINVLVKINDPCSCFFVPGLKEQIEQILKELKLLRFLVCFVSNKCIVPQYRCTTFYTRALIEASYIAMVAWLYLPIYGNGNQDLAPSEVSRLLSDFMEMKIKSIEPGISRNSIYIDVLQALKSTIPQAQKKHVEIPTHSLTVGLSDQMANLQEMLCLLRDNLIHLPILDLEFHLQDMDSVIVDAGLLIYSLYDIKGQMEDTSLDVINWALGFDLPRNIEPIKVMAYLVMQKAFHCNLPRIHGLGYVDFLLKNLNDFQDCYSDSLAFLKNQLQVIQTEFESLQPFLKVVAEEPHNKLKTLNEDCATQIIRKAYEVEYVVDACINKEALHWCLERWLLDIIEEITCIKAKIQEKNTVEDTMKTVIARTSSKLARTPRMKEEIVGFEDVIENLRKKLLSRTKGQDVISIHGMPGLGKTTLANRLYSDRSVVSQFDFCAQCCVSQVYSCKDLLLSLLRDAIGEESERRELPDNELADMLRKTLLPRRYLILVDDVWDNSAWDDLRGCFPDVNNRSRIILTTRHHEVAKYASVRSDPLHLRMFDEVESWKLLEKKVFGEQSCPPLLKNIGLRIAKMCGQLPLSIVLVAGILSEMEKDVECWEQVANNLGSHIHNDSRAIVDQSYHVLPCHLKSCFLYFGAFLEDRVIDISRLIRLWISEAFIKSSEGRSLEDIAEGYLENLIGRNLVMVTQRAISDGKVKACRLHDVLLDFCKERAAEENFLLWINRDQITKPSSCVYSHKQHAHLAFTEMHNLVEWSASCSFVGSVVLSNKYEPYFHDLSSLHDFSISRILPNFKFLKVLDLEHRVFIDFIPTELPYLRYFSALIDQNSIPSSISNLWNLETLILNRRSADSHNRVLLPSTVWDMVKLRHLHIPNFSPENKKALLKNSPNLDDLETLSYPYFARVKDAELMLRKTPNLRKLTCKVKCLEYLHQYHALNFPIRLEILKLYRSNAFKAIPFCISAPNLKYLKLSGFYLDSQYLSKTADHLKNLEVLKLYYVEFGDHREWKVSNGMFPQLKILKLEDVSLMKWIVADDAFPNLEQLVLRGCQDLMEIPSCFMDILSLQYIEVEDCNESVVKSAMNIQETQVEDYQNTNFKLVLIEKWPKFYKLFSQLSLPRGLVLHLGIESVSSDEKEKKLTVTGDVDADEVQLVVEKLRKCGMPGL
What is the function of this protein?
Confers resistance to late blight (Phytophthora infestans) races carrying the avirulence gene Avr1.  Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein.  That triggers a defense system including the hypersensitive response, which restricts the pathogen growth.
What are the official names of this protein?
Putative late blight resistance protein homolog R1A-10.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: KTHY_PSEAE
Sequence: MTGLFVTLEGPEGAGKSTNRDYLAERLRERGIEVQLTREPGGTPLAERIRELLLAPSDEPMAADTELLLMFAARAQHLAGVIRPALARGAVVLCDRFTDATYAYQGGGRGLPEARIAALESFVQGDLRPDLTLVFDLPVEIGLARAAARGRLDRFEQEDRRFFEAVRQTYLQRAAQAPERYQVLDAGLPLAEVQAGLDRLLPNLLERLNG
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NTPPB_RHIME
Sequence: MKPLLILASASPFRRALLSNAGLAFEARAAAIDERALEQPLEASGASPADVALALAEAKAKDVARYFSDALVIGSDQTMSLGTRVYHKPRDMTEAAEHLRSLSGRMHSLNSAIVLVRNDEVVWRHVSTANMTVRPLSDGFIDRHLAKVGEKALTSVGAYQLEGEGIQLFERIEGDYFTILGLPMLPLLSKLRELGAIDA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ID4_XENTR
Sequence: MKAVSPVRPQSRKAQVPAVCGELALHCLSEHSLGVARYKMEEEETLCLQYDMNDCYSRLKRLVPTIPPNKKVSKVEILQHVIDYILDLQLALDTHPVLLRQQPPTRTPLTDLNTDPAALVVNKQGDSILCR
What is the function of this protein?
Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity.  Inhibits the activity of both neurogenic (neurog1/neurogenin, neurod1/neuroD) and myogenic (myod1/myoD) bHLH factors (By similarity).
What are the official names of this protein?
DNA-binding protein inhibitor ID-4, Inhibitor of DNA binding 4, Inhibitor of differentiation 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS1_DECAR
Sequence: MTTITIALSKGRIFDETLPLLAAAGIVPKENPETSRKLIIETNQPNVRVVIVRATDVPTYVQYGAADLGVAGKDVLIEHGGEGLYAPLDLNIAKCRMMVAVPEGFDYENAVRQGNRLKVASKYTKTAREHFASKGVHIDLIKLYGSMELAPLAGLADAIVDLVSTGGTLKANKLVAVEDIMGISSRLVVNQASLKVKRETLQPIIDAFAQAVEK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAD_SINFN
Sequence: MARSATSDARKKDTREKIELGGLIVKAGLRYEKRVLLLGALVDLSRRLNSDESERARLIAIGAEAFGDDGE
What are the official names of this protein?
Probable conjugal transfer protein TraD.
What is the protein family that this protein belongs to?
Belongs to the TraD family.