PharMolix/UniProtQA huggingface dataset:
Protein: PANC_BARBK
Sequence: MRVLKTIAEVRQHLTEERRLGLSIGFVPTMGALHHGHLALVQKAREMCDRVLVSIFVNPKQFGSHEDFEVYPRDLLSDCTLLNKEAVEYVFAPSVEEMWPLGNDTIVEVEGLSRILMGELRPGHFCGVTSVVAKLFNIVQPDKVFFGEKDFQQLLIIRRMVKDLAFPIEVIGVPILRDSDGVASSSRNQLLTPEDRKAAKIIPESGKAAEKLYRQGERSVDKLCKAVRDILQQELRAIVESVDLRNMETLSAIKGTLDAPAVLLLTVRFGDVRLIDQYILQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPE51_MYCTO
Sequence: MDFALLPPEVNSARMYTGPGAGSLLAAAGGWDSLAAELATTAEAYGSVLSGLAALHWRGPAAESMAVTAAPYIGWLYTTAEKTQQTAIQARAAALAFEQAYAMTLPPPVVAANRIQLLALIATNFFGQNTAAIAATEAQYAEMWAQDAAAMYGYATASAAAALLTPFSPPRQTTNPAGLTAQAAAVSQATDPLSLLIETVTQALQALTIPSFIPEDFTFLDAIFAGYATVGVTQDVESFVAGTIGAESNLGLLNVGDENPAEVTPGDFGIGELVSATSPGGGVSASGAGGAASVGNTVLASVGRANSIGQLSVPPSWAAPSTRPVSALSPAGLTTLPGTDVAEHGMPGVPGVPVAAGRASGVLPRYGVRLTVMAHPPAAG
What is the function of this protein?
Plays a role in response to starvation and stress, likely environment within the host.  Inhibits canonical autophagy in infected mouse RAW264. 7 macrophages.  Inhibits autophagy and enhances intracellular bacterial survival when expressed in human macrophage-like THP-1 cells.  Inhibits Toll-like receptor 2 (TLR2)-dependent signaling leading to autophagy inhibition, increased intracellular bacterial survival, reduced phagocytosis and reduced secretion of interleukin 6 (IL-6) and IL-1 in infected mouse primary bone marrow-derived macrophage (BMDM) cells.  Required for virulence and persistence in the lungs and spleens of intranasally infected C57BL/6J mice.  Blocks the antibacterial effects of TLR2 activation, suppresses MHC class II-dependent antigen presentation, and reduces IFN-gamma and TNF-alpha-producing CD4(+) T cells during infection in C57BL/6J mice.
What are the official names of this protein?
Transporter PPE51, Proline-proline-glutamate family protein 51, PPE family protein 51, Protein PPE51.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
Protein: YOEC_BACSU
Sequence: MHIVQPIRSLEKIQEVKQYLLNKNKRDYFLFIFGINSALRISDILPLQVKDVQNKDHLWATESKTKKKRKILILESLKQEIYEYTKDMKENEYLFKSVRTRKPISRIQAYRILREAAAACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSITMRYIGIDEDTTRAAYKVFGGL
What are the official names of this protein?
Probable integrase/recombinase YoeC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: SPAT_BACIU
Sequence: MEVKEQLKLKELLFIMKQMPKTFKLIFTLERSLFLKLIRFSIITGILPIVSLYISQELINSLVTIRKEVSIVITIFLTYLGVSFFSELISQISEFYNGKFQLNIGYKLNYKVMKKSSNLALKDFENPEIYDKLERVTKEISYKPYQIIQAIITMTTSFVTLLSSIAFLMSWNPKVSLLLLVIPVISLFYFLKIGQEEFFIHWKRAGKERKSWYISYILTHDFSFKELKLYNLKDYLLNKYWDIKKSFIEQDTKILRKKTLLNLIYEIAVQLVGAVIIFIAIMSAFAGKIMVGNVMSYIRSVSLVQNHSQSIMTSIYSIYNSNLYMNQLYEFLELKEEKSQGHKKPIVEPIHSVVFQNVSFIYPNQGEQTLKHINVSLHKGERVAIVGPNGSGKKTFIKLLTGLYEVHEGDILINGINIKELDMDSYMNQIAALFQDFMKYEMTLKENIGFGQIDKLHQTNKMHEVLDIVRADFLKSHSSYQFDTQLGLWFDEGRQLSGGQWQKIALARAYFREASLYILDEPSSALDPIAEKETFDTFFSLSKDKIGIFISHRLVAAKLADRIIVMDKGEIVGIGTHEELLKTCPLYKKMDESENYMNPLEEEGSKWKEALYQG
What is the function of this protein?
Probably implicated in the export process of the lantibiotic subtilin.
What are the official names of this protein?
Subtilin transport ATP-binding protein SpaT.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSCB_SHEB8
Sequence: MNYFELFKFSPAFDIDTALLAERYRELQRAVHPDKFANDTEQQKLLSVQRTAQVNDGFQTLKDPIRRAEHMLSLRGIELSHETTTVKDTGFLMQQMEWREALEDIRDSADPQASIDELYQSFAQYRAQLTQQLTQLLTSEQAEDALLAADQVRKLKFMAKLHDELTRVEDALLD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: NADD_BUCAP
Sequence: MKEIYAIFGGNFDPIHYGHITSAEKLSREISIKKIILLPNYGPPHRSKTKTSIIDRLKMIKFAIKDNKLFTISYLETKKNTTFYTIETLKKIRKKIGYLQPLCFIIGEDNLNNLNIWKDWKKILSLSHLLICPRIHIKKSNPKLKKWISDHTTKNSNLLHKKPFGFIFFSKMSMLNISSTAIRKSYYEGKSACGLLPSKIDKYILSKNLYKIYNQN
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RS5_STUS1
Sequence: MANNEQKRDEGYIEKLVQVNRVAKTVKGGRIFTFTALTVVGDGKGRVGFGRGKSREVPAAIQKAMEAARRNMIQVDLNGTTLQYATKAAHGASKIYMQPASEGTGVIAGGAMRAILEVAGVHNVLAKCYGSTNPVNVVHATFKGLKAMQSPESIAAKRGKSVEEIS
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RF1_STRPM
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTRETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKMDEVIDALVMYDQTKKLESLNN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_STAAE
Sequence: MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVRRLYEGKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEAMLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYESLKVAADICVFTNDNIVVETL
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHHA_XENLA
Sequence: MPAVRIVILAICCGLLLVPVRCCGPGRGPVGRRRYMRKLVPLHYKQFVPNVPEKTLGASGKSEGKIHRGSERFIELVPNYNPDIIFKDEEKTGADRLMTERCKDRVNALAISVMNMWPGVKLRVTEGWDEDGHHAHDSLHYEGRALDITTSDRDRNKYGMLARLAVEAGFDWVYYESKAHIHVSVKADNSLGVRSGGCFPGTAMVMMGTGERKPLSELKIGDTVYTTDETGQLITSVVLLFLHRNPYKTATFVLIEAEGHPSKLLVTPNHLLFIQSSSSAGFLPTFAYRVQIGDLVQIYVNGTQVQSSKVVRVSLEEQTGVYAPMTEHGTLLVDGVLTSCYATVESHTLAHVSLAPLRLFQGIASMLPDLDMSDGVHWYCHILYVLAKYVLWWDMP
What is the function of this protein?
The dually lipidated desert hedgehog protein N-product (DhhNp) is essential for a variety of patterning events during development (By similarity).  Involved in the early induction and patterning of anterodorsal ectoderm, nervous system and somites.  Induces ectopic cement gland formation in embryos (PubMed:7671800).  Binds to the patched (PTCH1) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes (By similarity).
What are the official names of this protein?
Desert hedgehog protein A, Cephalic hedgehog protein, Desert hedgehog protein 1, DHH-1, X-CHH.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
[Desert hedgehog protein A N-product]: Cell membrane; Lipid-anchor. SUBCELLULAR LOCATION: [Desert hedgehog protein A]: Endoplasmic reticulum membrane. Golgi apparatus membrane. Secreted. Cell membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane.
Protein: RL31B_POLAQ
Sequence: MKPGIHPEYREIVFVDVSNNFSFKTRSTMSTRETIKWEDGNEYPLAKIETSSESHPFYTGTQKIMDTAGRVEKFRQKFGTKAVAKASGDGAAKTAEKKAAAAEAKAAEKPAKKKA
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: SPEB_NEIMF
Sequence: MQYSTLAGQTDNSLVSNNFGFLRLPLNFMPYESHADWVITGVPYDMAVSGRSGARFGPEAIRRASVNLAWEHRRFPWTFDVRERLNIIDCGDLVFSFGDSRDFVEKMEAHAGKLLSSGKRCLSLGGDHFITLPLLRAHARYFGKLALIHFDAHTDTYDNGSEYDHGTMFYTAPKEGLIDPSRSVQIGIRTEHSKKLPFTVLTAPQVNEDSVEETVRKIKETVGNMPVYLTFDIDCLDPSFAPGTGTPVCGGLSSDRALKILRGLTDLDIVGMDVVEVAPSYDQSDITALAGATIALEMLYLQGAKKD
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: TCPR1_MOUSE
Sequence: MPTSVLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQCCWGIAGDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWPWSDVSGLQHRPLDGVALPSPHWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDSWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYREDVSHPNPEGSSWSLVETPGEVVQISCGPHDLIWATLWEGQALVREGVCRNNPKGSYWSMVEPPGSENGIMHVSAGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPSELSGKTWKAIVVGRESDRSHSGSSSSLLSAGCFFGDEVRGSGTESAPSDTDASLEVERQGPEQPLPKEALDNSTNLKGSLSKGHETSGNTDHSTENACLTEGKEKAPETSRSDECRGPASTPAELPWTNIDLKEPKKVSNQPAAGFPETAGLSSLGLFPMGMEEPYGADDHPLWAWVSGGACAVEAGSTLKWFTIQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAAATEQDMNDWLALLSLSCCESRKVHGRPSPQAIWSVTCKGDIFVSEPSPDLEARERLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRFMWSDVTGLQECTKAGTKPPSLQWTWVSDWYVDFSVPGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPITLSDVSIIPESAHADGRGHNVALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGGWDHISVRANATRVPRNMSRDREARGPGPVCC
What is the function of this protein?
Tethering factor involved in autophagy.  Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes.  Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity).
What are the official names of this protein?
Tectonin beta-propeller repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TECPR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes (By similarity).
Protein: RSMG_STRP3
Sequence: MTPQDFYRTLEEDGFSLSSKQKEQFDTYFKLLVEWNTKINLTAITEENEVYLKHFYDSIAPILQGFLANEPIKLLDIGAGAGFPSLPMKILFPNLEVTIIDSLNKRISFLTLLAQELGLENVHFFHGRAEDFGQDKAFRGQFDVVTARAVARMQVLSELTIPFLKIGGKLIALKAQAADQELEEAKNALCLLFGKVIKNHSYQLPNGDSRFITIVEKKKETPNKYPRKAGLPNKKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL631_MIMIV
Sequence: MSKNNSKSTQGAPLDYIPGITTINQPVFMDDSVLTMNPTMNVPTTNTLISPIPVTTSKSSQLDSAHPTVVHIGDNHPEPKNESKTQPKIESKKEPTLKQEEQTIQAEEEAQKIAKEETRESFLRYGGEIIIDIMLGILLGIAVNMLTDYIASIFGLKGTAKFPIQLVLIVIVLYMLRINPDISFPLRSRTDTYGVIFIPIFITAQRNFAIFFSELYNIF
What are the official names of this protein?
Uncharacterized protein L631.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROF3_MAIZE
Sequence: MSWQTYVDEHLMCEIEGHHLSSAAIVGHDGAVWAQSTAFPQFKPEEMTNIIKDFDEPGFLAPIGLFLGPTKYMVIQGEPGAVIRGKKGSGGITVKKTGQALVIGIYDEPMTPGQCNMVVERLGDYLVEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-3, Pollen allergen Zea m 12, ZmPRO3.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PYRK_PYRFU
Sequence: MLRRVSIEETWEVAKNIKAFRLSEKLEFTPGQFIMLWLPGVEEKPLSLADKNLIMVKKVGRFTNELFKLKEGDYVWIRGPYGHGFSGKGKSVALIAGGIGIPPIYALAKYGNFKRSILIYGARTKEEIALPKDIESYVDEVIITTDDGSYGIKGFPTDVLMERRSEFDYVYACGPEIMLAKILEIMEFENVEVSAERYMKCGIGVCGSCALGPYLVCRDGPVFSGKQLINTEFGKYSRTPDGRIKPL
What is the function of this protein?
Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
What are the official names of this protein?
Probable dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit, Dihydroorotate oxidase B, electron transfer subunit.
What is the protein family that this protein belongs to?
Belongs to the PyrK family.
Protein: Y1503_PSE14
Sequence: MLNYLWFFLAALFEIFGCYAFWLWLRQGKSALWVIPALISLTLFALLLTRVEAAYAGRAYAAYGGIYIVASIAWLGLVERVRPLGTDWLGLAFCVIGATIILLGPRWSAA
What are the official names of this protein?
UPF0060 membrane protein PSPPH_1503.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YCF78_HELSJ
Sequence: MFLVYLRNCMDFFFNSSFNYSLTSIDFYKTIFLIFANKIKNNFLYIISFQWFFNITYIINQLPSIDDELYIPIVRDFFNFNSLITYIYNISLTQIFSIFSFSAIHVYFIKRLYSENLTSILPALSGYFISEILFIICIYSGITNLFIILANWERFFIISGIIFFFYEGVNFIKENKNKNIYLKIPFIKHSTFFNSYRFFNFKEFFLGVFLFCLDSPSIFTLVSNLSLTPTVSNFEFFINSSFIQLVLFILIRSFFFYLSFIIIYPFILNKIHHNTYFQSDTLKKINIFIQKGFGMLLIFFSVSSIPFYTIEYFLGYLLGIIPKDISLFFTQLDPYFLSDSPGFYEQFYYGNTVVPFKAAKFDRGRYLLYPAYRELPPSYEDFIFKPIYLEWTKTLKSNNYIDRYLGSQKTTMQYIQTKATPIIKFFENLFPDANVRKSNKRKKILTQLLTDKFLGSHTKLNTYFNVPYAEKLLFFNRLSKSAFRINNKQYYNDLILSSIEEFVTFNENLIPNFETLTPFDKCTYRFSLSKNLLTSRLKPFVDFLDLFSAPEFDITPIYVKMAENILSTYDRKKFFAPLANFFKDETLNESKVKKKNAQPSLSREIEAIQGKIPLESILTEGIVALFPEWAYIKMELVGKLGSIIKEYQRYFNFLEIFNLYLRGHSFKLTVKQSIDLHYRQLYQTEAISYLRHYFNNNSYRKIRDDLDNFSKVLKINFIENTKNKTNKIKNLNTREDSKKLLISLEKDSKKFMKYLLFKTTRSFASKVYNHQFKGTLIDLIQWFSYSPYTSSMFKEINTKEMENVFIEAEEPSYLLSLNNDVKKYYPIIKYDQAFYKKDALDKGIIFDHILYKSLIEELYDDDLTLENSESLKNENKLSKKNLSLINSNIISPNQNIFDLLNMIIDYITITNYSLSKIDTLLNPFIEYMSFEPLCASNHNNLFVLSTAHYSINDIDLPVKNHNTNKWPLPSNILDYLVYNISDDKVSFKNPLAYIGMFLQIPYEKFGIDYKNTYIFKVDNYEELNEHEVFDQYMDFFARYEDPAYESLQLKFINLFLENSLDDTNKALCKNYLFSKNFMVPTAYIDCPFPILQHFYLAKNLRQLFFVRSPIRGGYKWAGSYTNNIINNKLYTDLLKIYNRIILLWHKIYTSIIYKFKRNNHGTLAQLVE
What are the official names of this protein?
Uncharacterized membrane protein ycf78, ycf1.
What is the protein family that this protein belongs to?
Belongs to the ycf78 family.
What are the subcellular locations of this protein?
Plastid membrane; Multi-pass membrane protein.
Protein: PYRG_NOCSJ
Sequence: MNQATPTKHVFVTGGVASSLGKGLTASSLGSLLRSRGLRVTMQKLDPYLNVDPGTMNPFQHGEVFVTNDGAETDLDIGHYERFLDTDLSQIANVTTGQVYSSVIAKERRGDYLGDTVQVIPHITNEIKERILAMGGTGEDGRSVDVVITEVGGTVGDIESLPFLEAARQVRHDIGRENCFFLHVSLVPYIGPSGELKTKPTQHSVAALRQVGIQPDAVVCRADRELPPSIKKKISLMCDVDQDAVVTCADAPSIYDIPKVLHREGLDAYLVRRLDLPFRDVDWTVWDDLLRRVHHPKEEVTVALVGKYVDLPDAYLSVAEALRAGGFAHEAKVQLRWVASDECQTAAGAARNLQDVDAICVPGGFGVRGIEGKLGALTYARTHGIPTLGLCLGLQCMVIEYARNVVGLEKAGSTEFDPDTPEPVIATMAEQKAFVEGAGDLGGTMRLGLYPAALKDGSIAREVYGSSLIEERHRHRYEVNNAYRDQLEEAGLVFSGTSPDNSLVEYVELPRDTHPYYISTQAHPELRSRPTRPHPLFAGLVGAAIERQRELRFPIDETGLRREPEPDED
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PCKG_THEVO
Sequence: MLALDETEINDGAKRWIVSIAKHLNPSSIYVCDGTKEEFDDLASAMVKDGEMIKLNEKNFKNSYLYRSNATDVARTEERTFISARDKSFVGPLNNFLPLDRVKQVWNQFFKGAYTGKTMFVIPYALSSPESKFADFGIEVTDSKYVVLNLHYITRMGKGVIEKIGDRFIKGVHATGNLDPGNKFIIHMPWEKPEGVDADILSVNTNYGGNALLSKKCHALRIASVRAREEGWLAEHMLLLEVKDPQGKSHFITGAFPSASGKTNLAMISPPKDYRDAGWSTRLISDDISWIKIVDGKFMATNPENGFFAVVPGTNYNTNKNAMATLSKNTIFTNVGLTMSGDPWWEGLDPVYDELYDWKGNKRKIGGEPIAHPNSRYTSPLTNYPYLSDLYEDPEGVPVSAILFGGRRATLIPLVFEAFNWNHGVFLGATMGVERTAASEGKVGDLRRDPMAMRPFCGYNINEYFRHWIEIGERSKNKPKIFYVNWFRRRADGTFIWPGFAENFRVLEWIIYRTSHNDNAVETPIGYIPESLNLAGLNISEEDVKELFRIDKEGWKEEMNEIQKYFSELGNVPEEILKEFELEKKRLGY
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_VIBCH
Sequence: MSAKKPMALVILDGWGYREDNANNAINNARTPVMDSLMANNPHTLISASGMDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKAIMDGEFQHNKVLVAAIDKAVAAGKAVHLMGLMSPGGVHSHEDHIYAAVEMAAARGAEKIYLHCFLDGRDTPPRSAEASLKRFQDLFAKLGKGRIASIVGRYYAMDRDNNWDRVEKAYDLLTLAQGEFTYDSAVEALQAAYAREENDEFVKATEIRAAGQESAAMQDGDALLFMNYRADRARQITRTFVPDFAGFSRKAFPALDFVMLTQYAADIPLQCAFGPASLENTYGEWLSKAGKTQLRISETEKYAHVTFFFNGGVENEFPGEERQLVASPKVATYDLQPEMSSKELTDKLVAAIKSGKYDAIICNYPNGDMVGHTGVYEAAVKACEAVDECIGRVVEAIKEVDGQLLITADHGNAEMMIDPETGGVHTAHTSLPVPLIYVGNKAISLKEGGKLSDLAPTMLALSDLDIPADMSGQVLYS
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: YR314_MIMIV
Sequence: MSIVNSELDKSISTHIINNTNIIMAHYCNGSCAHNAYHTGYDKGMAVGMLAQQLLQSACPPVGVRTSYDLWGTVQPVRRYTCSYQCPYAGGAECSMCFARRVNPSGSPTYNPGQNSAPTILLSLAPGTSLSIGGIKYI
What are the official names of this protein?
Uncharacterized protein R314.
Protein: PG045_VACCW
Sequence: MLSMFMCNNIVDYVDDIDNGIVQDIEDEASNNVDHDYVYPLPENMVYRFDKSTNILDYLSTERDHVMMAVRYYMSKQRLDDLYRQLPTKTRSYIDIINIYCDKVSNDYNRDMNIMYDMASTKSFTVYDINNEVNTILMDNKGLGVRLATISFITELGRRCMNPVETIKMFTLLSHTICDDYFVDYITDISPPDNTIPNTSTREYLKLIGITAIMFATYKTLKYMIG
What is the function of this protein?
Plays a role in evading host innate immune response by inhibiting host inflammasome activation.  Interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells.  At the host mitochondria outer membrane, interacts with the BH3 domain of host BAK and prevents BAK from binding active BAX.  In turn, host apoptosis is inhibited.
What are the official names of this protein?
Apoptosis regulator OPG045, Protein F1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG045 family.
Protein: CRBG3_MOUSE
Sequence: MSVPVVYDKRRNLDCREEKEESNLAFVSQDEQDSSSFTILYEEPLQEEDRYTSAELRGSQSLLFPDTSSMPGLACERSESRTDLVHHFEKEGKLGEAFDGDNSEMFLSVEAKRYKIYPLALSPIYEDDSSQEDVLSSEVSPGHHGSSKSRESANQPSSVLSLLQSVSERLQRNFDGDDRQEAEEEEEEAVASGKDWRTEKREHVTFHLPDPSIPFYPEDNQEHAGIFKSYVEFSEPTTSSLQHGRWSEKELFLQKSDMTSKLHSSLKSAYHQYLQTSRTHSSETGTRFGGTLQEPVSKYFRVQDHAGRLSPYVENVDKQTLKCNPRPGKMIIYDLHGSKYKQEVYCNIPDATTWSFPNGALIKVVRGCWILYEKPHFQGQKCVLEEGERVLDRDWLLQNRKHPERNFVLGSIKRVLKDCSIPVIELCPKTDPGCSPIYIHRSVPNVEELNIPKSTSVTVKSGVWLAYPDIHFKGQATILEEDQGLFEISAAEMKSLHPLQMGGLKVEMPMNLKVILYEKPHFLGHTKEFSEHIDSVPTFLKSDKDFHGIGSIRVIGGVWVAYEKEHFKGQQFLLEEGDFEDSSACGALSGPIMSFRYLQANFIESSITLFESSHLESGKFIDITNQEISDLEEIGFGSETRSIHVKSGVWVAYHQKFFCGDQYILEKGKYKCFFDWGGSSNTILSIRPIQLEPLGINEPTHLLKAFSKAGFQGECIDFVKECADLTSFTPASFKVLRGCWLLLYYQEDGFYHQCVLEEGLYVDLTSCGCPSARIRALQPIDYVFEEPSISLFALEHCEGRELHLEDAVNSVLNKDLHFYTQSVWIKSGLWIAYEGSNFLGRQILLTPKEIPNWTAFSGWKTIGSVRPMKQPAVYIRIRNRAQDEYLTVTGNPADARTMSVCISPYSGKDTQIWHYCRGLFKSKASHTCLDVIGGRDTPGAKVALWTEHGQLRQKWRMSRNGTISSYLSDELVLDVKGGNYYDKTHVIVNQPLEGEETQKWDIEIL
What are the official names of this protein?
Beta/gamma crystallin domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: ACSA_MARN8
Sequence: MTDKQVYPVSPEVAERALVNKSQYEEMYRQSVEDPNTFWGEHGKRIDWIKPFTKVKNSTYDYNNLSIKWFEDGVLNASANCLDRHLEQRGDQTAIIFEGDDPSVSRNVTYRELYEETCKFANVLKDQGVKKGDVVTIYMPMIVETAVAMLACARIGAIHSVVFGGFSPEALAARIVNGKSRFVITADEGLRGGRAIPLKKNVDSALKHEDDAKVDKVIVVSRTGNDQVPWTEGRDLRYEDLMKNASAECQPEPMNAEDPLFMLYTSGSTGAPKGVLHTTGGYMVYASMTHQYVFDYHDGDVYWCTADFGWVTGHSYILYGPLANGAITLLFEGVPNYPDSSRMGQVVDKHKVNILYTAPTAIRALMAQGESCMDGTTRGSLKLLGSVGEPINPEAWEWYHRVIGNSKCPIVDTWWQTETGGILISPLPGAVDLKPGSATLPFFGVQPALVDNEGNILEGKTEGNLVILDSWPGQMRTIYGDHERFVQTYFSTYKGMYFTGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEVESALVAHDKVAEAAVVGYPHDIKGQGIYVYVTLVQGEEPSDELKKELVQWVRKEIGPIASPDVIQWAPGLPKTRSGKIMRRILRKIAANEHDQLGDTSTLADPGVVDELISSRAFK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HTPX_DESPS
Sequence: MFRVGLFLATNLAILLLLGLVMSLLGLDSRSASGLLLMAGCFGMGGSLISLALSKWIAKKATGAHVIEQPRNGTEEWLLHTVARQAQTAGIGMPEVAVYEADDMNAFATGMRRDAALVAVSTGLIRGMSQDEVEAVLAHEMSHIANGDMVTLSLIQGVLNTFVIFLSRMAANVIDNFLSSDEDGGGLGFFGYMAVSMLLEFVFGLFASMIVMWFSRRREFRADYGATELASKQKMIAALARLQQQHISSSLPEQVAAFGIRPRQGGLAELFRSHPSLEDRIAALEAI
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MER_SHIFL
Sequence: MRAKSAIFSRTSLSLCSARLLASSQWVPSSSRNSSAISSRLNPSRCADFTNFTRTTSASP
What are the official names of this protein?
Putative mercuric resistance protein.