PharMolix/UniProtQA huggingface dataset:
Protein: HPRK_RALPJ
Sequence: MELTGVIAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVLGKPEITYYQRLSEENRKRQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPISSAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGDSGLGKSELGLELISRGHGLVADDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQLVRRNDGEFERLPLDSQYLDVLGLPIHMVKIQVAAGRNLAVLVEAAVRNTILRLRGIDTLRDFMDRQRAAMQAEAASHSPQGRLL
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: MSA2_PLAF7
Sequence: MKVIKTLSIINFFIFVTFNIKNESKYSNTFINNAYNMSIRRSMAESKPSTGAGGSAGGSAGGSAGGSAGGSAGGSAGSGDGNGADAEGSSSTPATTTTTKTTTTTTTTNDAEASTSTSSENPNHKNAETNPKGKGEVQEPNQANKETQNNSNVQQDSQTKSNVPPTQDADTKSPTAQPEQAENSAPTAEQTESPELQSAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLNNSSNIASINKFVVLISATLVLSFAIFI
What is the function of this protein?
May play a role in the merozoite attachment to the erythrocyte.
What are the official names of this protein?
Merozoite surface protein 2, 45 kDa merozoite surface antigen, Merozoite surface antigen 2, MSA-2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: IRE1_SCHPO
Sequence: MKSLKGRLLFLRKFVFFSLLILLFAHGASSSSSSFNYFDKRTNGKANNELALFSPTADSPSSVDGVLELPSAENVFAESSLYNAFIVATVDGSLHSYDRITGQELWSLFTNANPGLSYTKDENSLLSSKFLSQSNFKSYNSTHGEFYSDSTLNISYLSDDDTVWFVEPIDGGILYAFNLQTGLVRLPHSIKDLVHASPIRLLNNNVFVGSKNTTLFTIDVSNGDIVSQYPSGHRYETHHSVHNLGTKRDSVPSGADSDLSFKDPSGKKLSESLDLLDDFNYQVTVSNKSFVDIARTEYFITIYSDSNVILDLVYIDWTPTKNEIMYESFHSSSFDSKLALSSYDSSLHIVDTHSKFIKQNIPLMSPAATVFDIVTLPHNKKIDKSQTPAKFPTSVLLRQPIDTYLETMFPQIARNKTEHVYINHIGNAWFAMSERHYPLVSLAPEASFLYYNGFYIPLNSIFGLHSLMATPKPFFALPGLPGYDIPSYVESEGSTKTLPSIGKKPIPLLDPNPISSTPISITFWVIMFLSVSFTIVTFFSILRIRSSEVRPLKSQKNTVSINNKIDTSKRRRKGKRRKRVSDEHSASSNFNEIESQASFEQNQTLDILSENIVEIQDKSTDPLQKSLDSSLKSHLPEATVIQNTDGSVTVNSLTVYPEVIGYGSHGTIVYRGVYEDREVAVKRVLMEFYDLASREITLLQQSDNHPNIVRYYCKQKSDQFLYIVIELCKCNLSDLIEKPIAYDDLFKSIDLVSLLYQIAFGVSHLHSLDLVHRDLKPQNILLVVNNSPNLSKTRVRALISDFGLSKKLDFNQSSLRNTTFEAAGSYGWRSPEILSGSLSQQSKEIQVKTREGRIRQASHATDIFALGCIFYYTLTGGMHPFGSHYDCEGNILKGNYCLVHLQSLGECGVLAADLIEDMIAFEPSKRPTIEVVLNHPLFWDYAKKLDFLIDVSDRFEVEERDPPSPLLQMLENNSKSVIGENWTTCLHSSLVDNLGKYRKYDGSKILDILRVLRNKRHHYQDLPESVRRVLGDLPDGFTSYFVEKFPMLLLHCYHLVKDVLYEESQFKRYLEY
What is the function of this protein?
Endoplasmic reticulum (ER) membrane-resident kinase/endoribonuclease involved in unfolded protein response (UPR) (PubMed:23066505).  Initiates the selective decay of a subset of ER-localized-mRNAs that is required to survive ER stress (PubMed:23066505).  Rather than relying on a transcriptional program to up-regulate genes that enhance ER protein folding capacity as in S. cerevisiae, S. pombe cells reduce the amount of specific proteins entering the organelle by decreasing the level of ER-targeted mRNAs using ire1-dependent mRNA degradation (PubMed:23066505).  The sole mRNA cleaved upon ire1 activation that escapes decay is the ER chaperone bip1 mRNA which is more stable and hence is present at an increased steady-state after ire1 cleavage (PubMed:23066505).  Promotes ER stress-induced ER-phagy and via up-regulation of the protein level of the ER-phagy receptor epr1 (Ref. 5).
What are the official names of this protein?
Sensor for unfolded proteins in the ER ire1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: TRPA_CHLCH
Sequence: MAQNRITRLMQQQKKLLIAYYMPEFPVAGATLPVLEALQEHGADIIELGIPYSDPIGDGPVIQNAAHTAIRNGVTLRKVLELVRKARNGEGCKKITVPIVLMGYSNPLFAYGGDCFLADAIDSGVDGVLIPDFPPEEAIDYLDRAKNVGLSVIFLIAPVTSPERIEFIDSLSTDFSYCLAVNATTGTAKLSGHAGDAAVEEYLHRVRQHTKKKFVVGFGIRDKERVESMWKLADGAVVGTALLEQLAASTTPQECAERAGTFWQSLR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: AROD_SALG2
Sequence: MKTVTVRDLVVGEGAPKIIVSLMGKTITDVKSEALAYREADFDILEWRVDHFANVTTAESVLEAAGAIREIITDKPLLFTFRSAKEGGEQALTTGQYIALNRAAVDSGLVDMIDLELFTGDDEVKATVGYAHQHNVAVIMSNHDFHKTPAAEEIVQRLRKMQELGADIPKIAVMPQTKADVLTLLTATVEMQERYADRPIITMSMSKTGVISRLAGEVFGSAATFGAVKKASAPGQISVADLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: AP3D_DICDI
Sequence: MFERTLVDLIRGIRNHKKNETKFINQCINEIKEELKGDMQKKTVAVQKLTYIQMLGFDISWASFKIVEVMSCNKFSSKRIGYLAASQSFNEGTDVIVLATHQIRKDFLSSNQSEAYLALNCLSNICTTDLARELANDILTLLSTQKTHILKRAITVLYKIFLRYPESLRPAFPKLREKLDDPEPSVVSCSVNVICELARRNPKNYLPLAPVLFRILTNTTNNYWMLIKIVKLFAALTPHEPRLGKKLIDPLTNIINSSPSVSLLYECIQTCITGMSDHIPLMKLCISKLRTLIEHNDQNLKYLGLLALNNIMKIHPKAVSEHRDLVLNCLEDDDISIRLRALDLLPGMTSKKNIGDIVFKLLDHLDNAEGQYKEQIIEKIIELCSMGTYQFITDFEWYINILVKLSQIQDSIHGKLIASQLLDVVIRVKIVRAYSTRQMIELLKNPKLMSNPTEGGMCEVLYAAAWIVGEFSGYVNRPIDALEAFLQPRVCVLPSHIQSVYMLNSLKVFSHACAKANGDKIPSLDDDDEEEEAQEEEDQNEITHEIVQECLEIIKSRLTIFTHSIYLNVQERACLINELLSFYTVTKEQGNNISKELISLFTEQLNPVGPKAQKKVPIPEGLDLDEWINDPKHQEPIEEDEDDDIFNTSTSSHQKKHHKHHRGGYDGDDDEDDETNSSHSGHSSSNFNRHPIDIQRQKEERLRKQANNPYMLGGKVSKKLSTNDPENIPVVQLTGDLGHLHVGASSNRPMPSKGSKKTKKHYTIDTTTEMPEGAKESDDEDEKDNKYKNDALSNINLSEPLTASDVLHTSRHRTDIIKEKEREMAMLAKKNAKLSPKSPPSTANYSEVTSPEIAPAKKATKKAAAGSNPPPPPTAKKSSKKPAATSSTTTTTKSTQAAAAVVAPPPVIVKKVLKTILDDDNFKITCEILKVSPSNETDNNQIKLTMKVQNKTDEDMSDVSISLKNPAEQCVSIKNSGEIGVLEADASTTHTELLNVVNVLNSQELQFTLLASPSSSPSITNQLSIDLPFSFFIVATKLPKDKFAEILQKSGQVSAMDSTKITGQSLTMPLVIEKLAQQLSIEVVQAHPNGQTASFYAKTTQNHHIAMLVKEKDGNISFDIKSPQSLLNQILVKEIAQLTFSSK
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is essential for the compartmentalization of the endocytic pathway.
What are the official names of this protein?
AP-3 complex subunit delta, Adaptor-related protein complex 3 subunit delta, Delta-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Endosome membrane.
Protein: MTAD_CARHZ
Sequence: MVNELTILIKNTTVLDLNKFAAVENDILIEGNKISKIGVDIEVNDKENLKIIDGSNKVALPGLINGHTHVAMTLFRGASDDLPLMDWLNNVIWPSESRLTGEDVYWGSLLGIVEMIKSGTTTFCDMYFFMDEVAHAVEQSGIRAILSRGMVALDPENGEKGLKESIDFIEKWQGKANGRITTALAPHAPYTCPPEFLKDVIWEAKRLNVPINIHISETLDEISIIKERYGTTPVRHLESLGLFEVKTIGAHLVHVDDEEIQILKRYQVGAIHNPQSNMKLASGIAPVAKMLEAGVLVGLGTDGAASNNDLDMIEELRAASYLQKVSSMNPEALNAKTSIAMATSLGARALGLTEVGLLKEGYKADIILLNTNETNFYPRHNIFNLIAYSAKGADVDTVIVDGEIIMEKRQLTRLDEEKIKFEANKRGLKLVAG
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: CDC37_CANAL
Sequence: MPIDYSKWDKIEISDDSDVEVHPNVDKQSFIRWKQRDIHEKRMQRNIEIKSILIQLTMYAKLNERVDYLLEKLTSTELLDSEKVMSKLNSEFDPQEKFDYDKLIKDKGSTLRKGLKDLKFDREEIENTPCYNEMIEDLFVQIKDDHPETKTDGDKLIEYLKEHRNRIDDVLSKQTIKLDDLLYQKAQLIVSDDLHTGFDRSFLNKDKPEEKEENQDKPKAPEAKKTTVTTTETINSPKPVEENTDKEILDELEILPATKEFAKIPSDNLSKAAEFLIKHPSICTEQQKDALIMTAFDLQLENKSDEAKHIVHQSLLLQYVGQLSDNGKAAPANVINAIKLFFSKIAAESSPAKHAFLEDVNQTFNHIKGRCEIIKEEQKQNAANKEGTGEEEEEEALIQLKALDDNTELSVNIPQEGTKEYEIFTTKLPIEFQNAIKTESIDEVNKEFAKLKIEDAERILEIFNECGVIGISGYIEDEKEFEELKKEYAHETANQEEDQSASVEDTVD
What is the function of this protein?
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity.
What are the official names of this protein?
Hsp90 co-chaperone Cdc37, Cell division control protein 37, Hsp90 chaperone protein kinase-targeting subunit.
What is the protein family that this protein belongs to?
Belongs to the CDC37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF62_ASFP4
Sequence: MNRGSISSGTPGLFVGSMRNTPFVVKINVIFLKVISNTAVSVFWRDRRIRFESDWLNSYFQK
What are the official names of this protein?
Uncharacterized protein C62L, pC62L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus C62L family.
Protein: YHBP_ECOLI
Sequence: METLIAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: CV039_MOUSE
Sequence: MAVAGSWQPPRPCEVYRAEWELCRSVGHVLHHYYVHGKRPDCRQWLRDLTNCREWEESRSAEAQRSLCESEQVRVQAAQKHTLVWALRQRPPTDWNLPLPQEKDK
What are the official names of this protein?
UPF0545 protein C22orf39 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0545 family.
Protein: PROB_MAGSA
Sequence: MSPLAAAKRLIVKIGSSLLVDDSTGQVRRGWLETLAADIAACKARGQEVIVVSSGAVAVGRRKLGLVPPLKLEEKQAAAATGQIRLAHAWQDALAHHQITVAQVLLTLDDSENRRRYLNARSTLETLLKLGAVPVINENDTVATAEIRVGDNDRLAARVAQMVSADALVLFSDIDGLYTADPRKDPDARFIPEVHELTPEIEAMAGDPGSAYGSGGMVTKLVAARICLSAGCRMAITRGEPMHPLKTIEDGGRCTWFLPNSEPRTARKQWIFGSMKPTGTLVLDAGAARALAQGRSLLPAGITEVSGAFERGDCVLVKDGSGKVLGRGLVAYSADDSRAIMGRKSGEIEAILGFRGRDELIHRDDLVMEG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR2_VIGUN
Sequence: DPRVRKQYIQEQGAPIVIKADGLAAGKGVTVAMTLEEAYKAVDSMLVQGDFGSAGCRVIVEEFLEGEEASFFALVDGENAIPLESAQDHKRVGDGDTGPNTGGMGAYSPAPVLTKELQSIVMDSIIIPTVKGMSAEGSKFVGVLYAGLMIEKKSGMPKLIEYNVRFGDPECQVLMVRLESDLVQVLLAACRGELNGVSLKWSPGSAMVVVMASKGYPGSYQKGTVIENLEEAEAVAPGIKIFHAGTAFDSEGRFIATGGRVLGVTAKGNDLEEACDRAYLAVENVNWPGGFLPSGYWLESSTSETSMLERE
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, Glycinamide ribonucleotide synthetase, GARS, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPF2_PORPU
Sequence: MIYLPLLLAEEIEGGLFDFNGTLPLMALQFLILMLLLNTIFYKPVTKILDERDEYIRTTLTTASSMLVKADELAAKYEEDLSKARRDAQAKIAASQKDAQSIVSEDIKKAQMNAEKLITEASKQLNIQKEEALKTLEDQVDTLSDQIKTKLLSSQSLK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', chloroplastic, ATP synthase F(0) sector subunit b', ATPase subunit II.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LEU1_CORGL
Sequence: MSPNDAFISAPAKIETPVGPRNEGQPAWNKQRGSSMPVNRYMPFEVEVEDISLPDRTWPDKKITVAPQWCAVDLRDGNQALIDPMSPERKRRMFELLVQMGFKEIEVGFPSASQTDFDFVREIIEKGMIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRNVVFRMDKVQVKKLATDAAELIKTIAQDYPDTNWRWQYSPESFTGTEVEYAKEVVDAVVEVMDPTPENPMIINLPSTVEMITPNVYADSIEWMHRNLNRRDSIILSLHPHNDRGTGVGAAELGYMAGADRIEGCLFGNGERTGNVCLVTLALNMLTQGVDPQLDFTDIRQIRSTVEYCNQLRVPERHPYGGDLVFTAFSGSHQDAVNKGLDAMAAKVQPGASSTEVSWEQLRDTEWEVPYLPIDPKDVGRDYEAVIRVNSQSGKGGVAYIMKTDHGLQIPRSMQVEFSTVVQNVTDAEGGEVNSKAMWDIFATEYLERTAPVEQIALRVENAQTENEDASITAELIHNGKDVTVDGRGNGPLAAYANALEKLGIDVEIQEYNQHARTSGDDAEAAAYVLAEVNGRKVWGVGIAGSITYASLKAVTSAVNRALDVNHEAVLAGGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).  Complements an E. coli leuA deletion (PubMed:8117072).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: Y1649_ALIF1
Sequence: MAITSKYSNKQIEQMLTEMVDVLDKHRAPADLSLMLVGNIATNVLNQEVPAEQRQIIAEKFAQALLSSLDKPKTH
What are the official names of this protein?
UPF0352 protein VF_1649.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: HTPG_BACTN
Sequence: MQKGNIGVTTENIFPIIKKFLYSDHEIFLRELVSNAVDATQKLNTLASIGEFKGELGDLTIHVELGKDTITISDRGIGLTAEEIEKYINQIAFSGANDFLEKYKDDANAIIGHFGLGFYSAFMVAKKVEIITKSYRDEAQAIKWTCDGSPEFTIEEVDKADRGSDIILYIDDDCKEFLEEARVSELLKKYCSFLPVPIAFGKKKEWKDGKQIETTEDNIINDTTPLWTRKPSELSDEDYKSFYTKLYPMSDEPLFWIHLNVDYPFHLTGILYFPKVKSNIELNKNKIQLYCNQVYVTDSVEGIVPDFLTLLHGVIDSPDIPLNVSRSYLQSDSNVKKISTYITKKVSDRLQSIFKNDRKQFEEKWNDLKIFINYGMLTQEDFYEKAQKFALFTDTDNKHYTFEEYQTLIKDNQTDKDGNLIYLYANNKDEQFSYIEAATNKGYNVLLMDGQLDVAMVSMLEQKFEKSRFTRVDSDVIDNLIIKEDKKNETLEGEKQEAITTAFKSQLPKMDKVEFNVMTQALGDNSAPVMITQSEYMRRMKEMANIQAGMSFYGEMPDMFNLVLNSDHKLIKQVLDEEEAACHPEVAPIQTEMNSVSKRRNELKDSQKDKKEEDIPTAEKDELNELDKKWDELKNKKEGIFAGYASNNKVIRQLIDLALLQNNMLKGEALNNFVKRSIELI
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPI2_LYMST
Sequence: MVGVRLVFTNAFVVTVLLTLLLDVVVKPAEGQSSCSLSSRPHPRGICGSNLAGFRAFICSNQNSPSMVKRDAETGWLLPETMVKRNAETDLDDPLRNIKLSSESALTYLTKRQRTTNLVCECCFNYCTPDVVRKYCY
What are the official names of this protein?
Molluscan insulin-related peptide 2, MIP II.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Secretory granules.
Protein: RM09_BOVIN
Sequence: MAAAAFAVPRGVQLRVLTERLLRGGVRELLRPRLSGSTPGSERDFSLSHSRGTVIVERWWKVPLAGEGRKPRLHRRHRVYKLVEDTKHRPKENLELILTQSVDELGVRGDLVSVKKSVGRNRLLPEGLAVYASPENKKLFEEEKLLRQEGKLDKIQTKAGEATVKFLRSCHLEVGMKNNVKWELNPEIVARHFLRNLGVVVAPHALKLPEEPITQRGEYWCEVTVNGLDTVRVPMSVVNFERPKTKRYKYWLAQQAAKGMASTSFQKI
What are the official names of this protein?
39S ribosomal protein L9, mitochondrial, L9mt, MRP-L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HUTG_CITK8
Sequence: MTQWQPASPTLWQGRDDSAEAANALRLFQTVTRSPTFSPEMYREKIALLGFACDEGVKRNQGRPGAAGAPDALRRALANLASHHGHDRLVDLGNIIAQAPDLEGAQQALRDAVRRCQQADMRTFVLGGGHETAFGHGAGLLDAFPHARVGIINLDAHLDLRRADHATSGTPFRQLAQLCDEQQREFHYACFGVSRAANTQALWDEAQQRGVTIVEDVDCDTAQAPLAQVIDSVDKIYLTIDLDVLPAWEMPAVSAPAALGVPLATVMRLVDAVCRSGKLQAVDMVEFNPRFDDDGNAARVAARLGWQIAHGWR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: NRK1_ASHGO
Sequence: MTSQLAGFKGTRGTLLVGIGGCSSSGKSTIAKLAVQVLEDAVLVHQDDFYRHDDEVPFDEEYQIGNWDVPEALDMAQFERELDHIRATGRPAAKLVHNGNIDDVGKFGISEEYLEELRRRYRGRISQPVVLVDGFMLYHDDKVAARFDCRLLVRAPYATMKARRASRGGYKTLDSFWQDPPFYFDKFVYKSYAATHARLFRNCDVEDRLVAPDVQEIYNGDEAQITCVLEQVLDAIAAAQC
What is the function of this protein?
Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN).
What are the official names of this protein?
Nicotinamide riboside kinase, NRK, NmR-K, Nicotinic acid riboside kinase, Ribosylnicotinamide kinase, RNK, Ribosylnicotinic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family. NRK subfamily.
Protein: RF2_HYPNA
Sequence: MSAEIRSLIEKIESSAALLRRRLDWDTATKRLDELTALSERPNFWDDPQEAQAMMRERQKLADGIALVQTLEKDVADAPELMELAEGDASMLADLEATLRRAAARAAEAELAALLSGEADGNDCYLQINAGEGGTESQDWASILRRMYVRWAEKRGYGVELLDERDGEEAGIKSATLQIKGENAYGWLKSEQGVHRLVRISPFDSSARRHTSFSSVAVSPVIDDKIDVEINPSDVRTDTYRASGAGGQHVNRTDSAVRLTHIPTNTVVQCQAGRSQHQNRDEAWKMLRSKLYELELQKRRAVADAQYADKSAIGFGHQIRSYVLQPYQMVKDLRTEVETSDTSGVLDGDIDRFLSAALAASVSKDQDA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSPE_SAGOE
Sequence: MNVLLGGLVIFATFVTLCNGSCYVIRHKIVPGETIKECTDLKGNKHPLDSRWRTEDCELCACRDIEISCCSLVSTPVGYDRHNCRKIFNKETCKISVVEKTDPNRPCGVSGWIS
What are the official names of this protein?
Beta-microseminoprotein E1, msp-E1.
What is the protein family that this protein belongs to?
Belongs to the beta-microseminoprotein family.
What are the subcellular locations of this protein?
Secreted. Note=Sperm surface.
Protein: VIE2_MUHVS
Sequence: MERVRGASSSDSVATLHGDHNYHCMATFKLDCTSARTRGVVSILEHRDPATVDDIFMQRVCHDINDVLRPVECLTSFPEYRRTLRVAVEAATELHGVSALSGQLTKFLEDHDGAMLPLAWPPNRYLRLTSGRKLGYLDVAEKLRKEYPMCNGPLEVLGVILGPGQSLYSDQHPVLLMGLTGTIFLHARGRPVWSPDYDPERDADRLFLAAESLQSFGREGLCRCDNVYTEDGGAPYATPEDPVLKNIVFTPHLGGKALHQQICKIKGHTWYLNGCPGMLKDRVFVATPDIPPFVRHVNLELFGHRFLPIGRVTRSPEDPECEMFIMVDAGGAIYGHMLDSGKVRRLADNFDQFMRMGTRRVISISRWLREVVSTPSTRRPRLGPRTTGSFS
What is the function of this protein?
Involved in the reactivation of latent MCMV in spleen cells.
What are the official names of this protein?
Immediate-early protein 2, IE2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: ABC8B_MOUSE
Sequence: MIKREISVRQQTCALLQKNLLKKWRLKRESLMEWVSSLLLLLFLYWYPHGHGATDLSSVPTKDLGRVDSFRQSGFMIGYTPVTSMTQQIMEKVAATPFMADKKVLGLLDEENIKELTESHAEIIRVIFSDTFSYHLKFQFDQRIPTSRELRDHNAHCDGLYEDVNCLIAIFWKEGFVALQAAINAAIIETTTNHSVMEELLSVSGKFMKIHPFVRQEGILTDFFIFTCIISFSPITYYVSINVARERKRMKGLMMMMGLRDPAFWLSWGLLYAGFVFIMALSLALVIKSVQFFILTSFMVVFSLFLLYGLSMITLAFLMSALVRKSVLTGLSVFLLTIFWGSLGFTSLYRYLPAPVEWTLSLFSPFAFTLGMAQLLRVDYDLNSNAPPDPASGSNLIIATNFMLVFDAFLYLALMMYFEKVLPNEYGHQHSPLFFLKSSFWLQTRKPAHVILEDGIDPVPSSGDSFEPVSPEFHGKESIRIRNISKEYKGKPNKIEALKDLTLDIYEGQITAVLGHSGAGKSTLLNILSGLSVPTKGSVTIYNNNLSEMADLENILRIAGVCPQANVQFDFLTVRENLRLFAKIRGIPPQDVEKEVQRVLLELEMKNIQNILAQNLSGGQKRKLTFGIAILGDSQIFLLDEPTAGLDPFSRHRVWNLLKERRADRVVLFSTQFMDEADILADRKVFISNGRLKCAGSSLFLKKKWGVGYHLSLQLKEVCVPENITSLVKQHIPAAKLSAEGEGKLLYTLPLETTYRFPELCQSLDSCPGLGIENYGVSMTTLNEVFLKLEGKASIDEPEVDIVGEGQTERSGDTERLMEMEQTLSSLRETEKTDGMALWRQQTCAIAKVRLLKLKHERKTLLSVLLILVVGICPFLFENISTKIRQSSYTWELSPHDYFLAPGQQPQGMLTQLLIINKTEASIDDFIHSVERQNIALEVDASGTRDGTDDPSYNGALIVSGNEKNHSFSFACNTKRLNCFPVLMDILSNGLLGMVKPSARIQTDRSTYLMDETIHPLEDLWKTAFWLILTSACPPYIAMSSVTDYKNRAWFQLRVSGLFPSAYWVGQAMVDIPLYCFVFLFMSLMDYLFRFPDTMFSIISHVIQIPCSVGYAISLIFLTYVISFISRKGKKNSGIWSLSFYIITVFSVAVILLAFDVDGTQYYIIFLIPPSTLVGCLILSLHLFIGQIFEEGQVIEPFLVFLIPFLHVFIFIFTLRCLEWKFGKKTMRKDPIFRISPRNNDVYQNPEEPEDEDEDVQMERMRTANALVSTSFDEKPVIIASCLRKEYAGKQKHCLSKKKAKIATRNVSFCVRKGEILGLLGHNGAGKSTSLKMISGDTKVTAGQVLLKGSREGDTPGFLGYCPQENALWPNLTVKEHLEIFAAVRGLRKSHAAVAITRLADALKLQDQLKSPVKTLSEGVKRKLCFVLSILGNPSILLLDEPSTGLDPEGQQQIWQAIRAIIKNTDRGALLTTHYMAEAEALCDRVAILVSGRLRCIGSIQHLKSKFGKDYLLEMKVKTLEQVEPLNTEILRLFPQASRQERYSSLMAYKLPVEAVQPLSQAFFKLEKVKQTFDLEEYSLSQSTLEQVFLELSKEQELDGLELEELDSSIKWKLLPQEEA
What is the function of this protein?
Mediates cholesterol and taurocholate efflux (PubMed:28882873).  Through the interaction with ABCA1 potentiates the cholesterol efflux to lipid-free APOA1, in turn regulates high-density lipoprotein cholesterol levels (By similarity).
What are the official names of this protein?
ABC-type organic anion transporter ABCA8B, ATP-binding cassette sub-family A member 8B.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane. Note=Predominantly expressed on the sinusoidal plasma membrane in hepatocytes.
Protein: TACHY_CAMFO
Sequence: MQCDFRVHQDARLARVYYFTEVWWMFIFKFLEPKMLINSVLFLAIWSSSFAEESSSSDATSNKRAAMGFQDMRGNKNLIPTSLEHNKLSKRTLMDFQDNKDSNAPDIEDNLSHEFEKRAPMGFQGMRGKKGYLTPDFEDSYFRDEKRAPMGFQGMRGKKVVSDDDYYKRAPMGFQGMRGKKSLEEVLGEIEKKAAMDYYDTRDKKTYVFEYPEDYEKRLLASIRGKLKEFPMEWEKRAPMGFQGMRGKKSLLDEIEELEKRTIMGFQGMRGKKNALENYIDYYLDPDMDFDKRAPMGFQGMRGKKDSDKRAPMGFQGMRGKRNTGQRFDTGINFNIRSSNEYQGTNNRRNALASCQLEKRSPFRYFEMRGKKNPRWELRGMFVGVRGKKWATAPYEDDSPFISVFDNTERIGVDGDSPAILGNSIS
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Tachykinins.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RAPA_SHEB8
Sequence: MPFALGQRWISDTESELGLGTVVQVEGRMVTVLFPATGENRMFSRAEAPLTRVIYNPGDSVESHEGWSLAVSELTEKDGIVIYHGIHSETGEQVTLRETLLNHNIRFNKPQDRLFAGQIDRLDRFGVRYQCQMLRHKLASSDLLGLQGPRVGLIPHQMWIAHEVGRRYAPRVLLADEVGLGKTIEAGLIIHQQLLTGRAERILIIVPDTLRHQWLVEMLRRFNLRFSVFDEDRCVEAYADHDNPFYTEQLVICSLELLRKKKRLDQALDADWDLLVVDEAHHLEWTEEAPSRAYQVVEALSEVIPGVLLLTATPDQLGHESHFARLRLLDPDRFYDYDAFLAEEDSYKDVAIAAEALAGNAKLPDAAINSLTELLGEKDISPSIRLIQAEGIDAEVQQAARSELLQELLDRHGTGRVLYRNSRASVKGFPKRFFNAYPHAMPDQYQTAARVSGMMGGHKSLEAKAAQALSPEKLYQEFEDNSASWWKFDPRVDWLIEFLKSHRSKKVLIIASQAETALSLEEALRTREGIQATVFHEGMSIIERDKAGAYFAQEEGGAQALICSEIGSEGRNFQFASHLVLFDLPLNPDLLEQRIGRLDRIGQKNDIQIHLPYLEDTAQERLMKWYHQGLNAFELTCPSGHVLYSEFAEDLLNVLVVDDSDELTNLLNHTQSRYKELKHTMEQGRDKLLEINSHGGEKAMAIVQRLAQNDGDTHLIGSVIRLWDIIGVDQEDKGENSIILRPSEHMMFPTYPGLPEDGVTVTFDRDTALSRDDIALITQEHPLVQTGLDLITGSETGTTSVAILKNKALPAGTLFLELIYMADASAPKSSQLYRYLPPTPIRVLLDKNGNDLSAKVDYASFDKQLSAVNRHIGGKLVTASQPILHPLFAKGEEYAQVVVDEMVAQAREKMTQQLSAELSRLESLKAVNPNIREEELEYLRNQMQELNTYLDASQLQLDAIRMVLVSHV
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.