PharMolix/UniProtQA huggingface dataset:
Protein: ATPD_BLOPB
Sequence: MSSMLVVARTYAQAIFDIAVEQKNINKWKSVLDLFSEISLNRLVQSLFFRCLEPKRLSDIFIAICEDYQKKQVDTFSKNIIYIMAENNRLLLLPIVFKEFTYLCSIYVHTVEIEIISAWPLKYNQLKKITDIMAKRLSKTVNPVHKVDKDILAGVIIRIGDTVIDGSIRGRIFRLNHVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NOS_DROME
Sequence: MSQHFTSIFENLRFVTIKRSTNAQQQQQQQQQQLQQQQQQLQQQKAQTQQQNSRKIKTQATPTLNGNGLLSGNPNGGGGDSSPSHEVDHPGGAQGAQAAGGLPSSSGTPLRHHKRASISTASPPIRERRGTNTSIVVELDGSGSGSGSGGGGVGVGQGAGCPPSGSCTASGKSSRELSPSPKNQQQPRKMSQDYRSRAGSFMHLDDEGRSLLMRKPMRLKNIEGRPEVYDTLHCKGREILSCSKATCTSSIMNIGNAAVEARKSDLILEHAKDFLEQYFTSIKRTSSTAHETRWKQVRQSIETTGHYQLTETELIYGAKLAWRNSSRCIGRIQWSKLQVFDCRYVTTTSGMFEAICNHIKYATNKGNLRSAITIFPQRTDAKHDYRIWNNQLISYAGYKQADGKIIGDPMNVEFTEVCTKLGWKSKGSEWDILPLVVSANGHDPDYFDYPPELILEVPLTHPKFEWFSDLGLRWYALPAVSSMLFDVGGIQFTATTFSGWYMSTEIGSRNLCDTNRRNMLETVALKMQLDTRTPTSLWKDKAVVEMNIAVLHSYQSRNVTIVDHHTASESFMKHFENESKLRNGCPADWIWIVPPLSGSITPVFHQEMALYYLKPSFEYQDPAWRTHVWKKGRGESKGKKPRRKFNFKQIARAVKFTSKLFGRALSKRIKATVLYATETGKSEQYAKQLCELLGHAFNAQIYCMSDYDISSIEHEALLIVVASTFGNGDPPENGELFSQELYAMRVQESSEHGLQDSSIGSSKSFMKASSRQEFMKLPLQQVKRIDRWDSLRGSTSDTFTEETFGPLSNVRFAVFALGSSAYPNFCAFGQYVDNILGELGGERLLRVAYGDEMCGQEQSFRKWAPEVFKLACETFCLDPEESLSDASLALQNDSLTVNTVRLVPSANKGSLDSSLSKYHNKKVHCCKAKAKPHNLTRLSEGAKTTMLLEICAPGLEYEPGDHVGIFPANRTELVDGLLNRLVGVDNPDEVLQLQLLKEKQTSNGIFKCWEPHDKIPPDTLRNLLARFFDLTTPPSRQLLTLLAGFCEDTADKERLELLVNDSSAYEDWRHWRLPHLLDVLEEFPSCRPPAPLLLAQLTPLQPRFYSISSSPRRVSDEIHLTVAIVKYRCEDGQGDERYGVCSNYLSGLRADDELFMFVRSALGFHLPSDRSRPIILIGPGTGIAPFRSFWQEFQVLSDLDPTAKLPKMWLFFGCRNRDVDLYAEEKAELQKDQILDRVFLALSREQAIPKTYVQDLIEQEFDSLYQLIVQERGHIYVCGDVTMAEHVYQTIRKCIAGKEQKSEAEVETFLLTLRDESRYHEDIFGITLRTAEIHTKSRATARIRMASQP
What is the function of this protein?
Catalyzes the conversion of L-arginine to L-citrulline producing nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7568075, PubMed:12804606).  Truncated isoforms (isoform 3-isoform 6) are able to form intracellular complexes with the full-length protein and serve as dominant negative inhibitors of the enzyme activity.
What are the official names of this protein?
Nitric oxide synthase, dNOS.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
Protein: VP7_ROTYO
Sequence: MYGIEYTTVLTFLISVILLNYVLKSLTRIMDFIIYRFLLIIVILSPFLNAQNYGINLPITGSMDTPYTNPTREEVFLTSTLCLYYPTEAATEINDNSWEDTLSQLFLTKGWPTGSIYFKAYTNIASFSVDPQLYCDYNLVLMKYDATLQLDMSELADLLLNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCLTTDTNTFEEVATADKLVITDVVDGVNHKLNVTTNTCTIRNCKKLGPRENVAVIQVGGSDILDITADPTTAPQTERMMRVNWKKWWQVFYTIVDYVNQIVQAMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: PPIL4_CRYNB
Sequence: MSVMLETSLGDLIIDLEVDKCPRTCENFIKLCKLKYYALNAFFNVSKNFIAQSGDPTATGTGGESLASYVYSQSPSGPRPPRYFTPEILNSLKHTHKGTLSMAVAPINPPGCGSQFFITLADNIDYLDGKHAVFGHVIEGLDTLDKINDAFTDKEGRPLQNIRIRHVEILEDPFPDPDNFMPIPQSPIRPPDDLSKVRIADTEDPNAVIPEEEAEELRRRTEAASSALTLEMIGDLPFAAVRPPENILFVCKLNPVTQDEDLELIFSRFGKILSCEVVRDKKSGDSLQYAFIEFDEREAAEQAYFKMQNVLVDDRRIWVDFSQSVAKMNRSMLSSSNPTGRGGRGGRGGRGGNYSGRRDGDRDRDRDSGWSSRRDAPDSRRPPPPPVPMSSSRDVGGTEGYGLVFDDRSAPSSRGSKRDRERSPKRERDRERERDRSPRRDRDRERDRSPRRDRDRERDDHDRRDRDRNGRDRERNGDRERYRERSRERENERYRERDDRDRRR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 4, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: UXUA_FLAJ1
Sequence: MEQTLRWFGPNDPVSLQDIAQTGATGIVTALHHIPNGEVWSIDEIIKRKVEIEHQDGDPKKGASGLTWSVVESIPVHEDIKKQTGNYIQYIENYKESIRNLALCGIKCVCYNFMPVLDWSRTDLSYTVEDGSKALRFDINAFAAFELFILKRPGAENEYSDEQKQKAKSYFEAMTAEDKVKLQQNILAGLPGAEEAYTVEDFLVTLSAYNHIDRQALKNNLFHFLKEIVPVAESKGVLMAIHPDDPPYPILGLPRVVSTEEDLIELMNAAPSKSNGFTMCTGSYGVRADNDLPGIVRRHGDKMNFIHLRSTQRDEEGSFYEANHLEGDVDMYEVVKAILEVEKRNNSKLPMRPDHGHQMLDDLKKKTNPGYSAIGRLRGLAELRGLELGIKRSL
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: FTSK_LACLA
Sequence: MSESKKMPAKKKTTRRNTKKEQQKKAATRKMIAFFVGLLLILFALARLGIVGVLLYNIVRLFVGSLAIVFLLLLAGLMIISVFRKQVLKENKRIIPAIILTFIGLMFVFQIRLHQGFNETFHLIWSDLMAGRVIHFVGSGVIGALITEPAKALFSVIGVYIIAAVLWLVAIYLMIPGLFPKMREDLHQRLAKWKEKHAEKVEAKKAAKALAELEKKQAVAEREELPEAAENSLFTSAPTEIPINIPEAPFEENETESPVLAEVPLDDEPVNFSNTNNYNGNYKLPTIDLLAEVPVKNQSGERENVRKNIGILEETFKSFGIGANVESAVVGPSITKYEIKLATGTKVSRVVNLSDDLALALAAKDIRIEAPIPGKSLVGVEIPNAEVAMVGFREMWEAGKTNPSKLLEIPLGKSLDGGIRTFDLTRMPHLLVAGSTGSGKSVAVNGIITSILMKALPSQVKFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASRALQKVVDQMEERYELFSRYGVRNIAGYNEKVQRYNAESDEKMLELPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDTNGAEKLLGRGDMLFKPIDENHPIRLQGAFLSDDDVESVVTFIKDQSEAQYDESFDPGEVDESQVGTGASNTGSGDPLFEEARNMVIMAQKASTAQLQRALKVGFNRASDLMNELEAQGIVGPAKGTTPRKVLVSPDGEFIGGVEE
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the difSL recombination site, which is located within the replication terminus region.  Required for activation of the XerS recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: PFD5_DICDI
Sequence: MSEPQQQQVNLGSLSLEQLQMVREQVEAEIQQLSESIQQLKHASNKYIEAKEAMGGLKGTDGKDMLVPLTSSIYLPGKINSNEKVLVDIGTGYYVEMGIEQGQNFSNRKVQLITEQVNKVQTAINMKRQNLESIVQVAQSKISLYKQQQAQQSQQQVQQK
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Probable prefoldin subunit 5.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
Protein: IL6_ORCOR
Sequence: RFTSAFSLGLLLVTATAFPTPGPLGEDFKDDTTSDRLYLTSPDKTEALIKYILGKISAMRKEMCEKYDKCENSKEALAENNLNLPKMAEKDGCFQSGFNQETCLMRITTGLLEYQIYLDYLQNEYEGDKEAIEAVQISSKALAQILRQKVKNPDEVTTPDPTTNASLMNNLQSQNDDWMKNTKIILILRSLENFLQFSLRAIRIK
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity).  'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity).  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity).  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NORV_SALAR
Sequence: MSILVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRSEIDLADIDYIIINHAEEDHAGALTELMAQIPDAPIYCTANAIDSINGHHHHPEWNFKVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYMTGDAVLFSNDAFGQHYCDERLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRIMADAIAQGINEVDPNVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLRFRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDLDALELCRQHGRDIARQWALAPLPETTQKTTPAEEITTCAAADLGPKMQCSVCQWIYDPALGEPLQDVAPGTPWSDVPDNFLCPECSLGKDVFDVLATEAK
What is the function of this protein?
Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes.  Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified.  NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center.  Also able to function as an aerobic oxygen reductase.
What are the official names of this protein?
Anaerobic nitric oxide reductase flavorubredoxin, FlRd, FlavoRb.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_STAHJ
Sequence: MKIFDYEDIQLIPNKCIVESRSECDTTVQFGPKAFKLPVVPANMQTVMSEELAHWFAKNDYFYIMHRFDEAARIPFIQKMQKDGLFASISVGVKANEFKFIEELADKQLVPEYITIDIAHGHSDSVIKMIKHIKKYIPKTFVIAGNVGTPEGVRELENAGADATKVGIGPGRVCITKIKTGFGTGGWQLAALNICSKAARKPIIADGGLRTHGDIAKSIRFGASMVMIGSLFAAHEESPGETVELDGKRYKEYFGSASEFQKGEHKNVEGKKMFVEHKGSLKDTLVEMQQDLQSSISYAGGKDLKSLTTVDYVIVRNSIFNGDKD
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: RENT2_HUMAN
Sequence: MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENFFSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISDVNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVGIFTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKFNLSFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELSEDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPGEYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKENKEVSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKLIVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYARLVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKNDTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHLDARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKLPWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLGMEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPDGSPSSLDPPEHLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHPFPIDIDYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENETDEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHLKSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQAEQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPNADLIFKTGGRRR
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC).  Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD.  In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1.  Binds spliced mRNA.
What are the official names of this protein?
Regulator of nonsense transcripts 2, Up-frameshift suppressor 2 homolog, hUpf2.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cytoplasm.
Protein: YBEY_BACCQ
Sequence: MSLLIDFIDETEEVKEEYVNLIREILGKAAQMEKIEDGAELSVTFVDNERIREINRDYRDKDQPTDVISFAMEEMGEGEMEIVGVEMPRMLGDLIISIPRAKEQAEEYGHSFDRELGFLALHGFLHLLGYDHMTEEDEKEMFGRQKEILEAFGLGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR4A4_HUMAN
Sequence: MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMSFFLAGLTFIDIIYSSSISPRLISDLFFGNNSISFQSFMAQLFIEHLFGGSEVFLLLVMAYDRYVAICKPLHYLVIMRQWVCVLLLVVSWVGGFLQSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLACTDTHVIGLLVVANGGLSCTIAFLLLLISYGVILHSLKKLSQKGRQKAHSTCSSHITVVVFFFVPCIFMCARPARTFSIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Putative olfactory receptor 4A4, Olfactory receptor OR11-107.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y5206_BURPS
Sequence: MMLHIPGVLTKEQVAQCRDILDAADWTDGNATSGAQSALAKRNRQLPEGSPAARAAGDAIQDALACNALFFSAALPLKVFPPLFNRYAGGDAFGTHVDNAIRLLRGTDFRVRSDLSATLFLEEPEHYDGGELCVEDTYGVHRAKLPAGDMVLYPASSLHHVTPVTRGARVASFFWIQSMVRDDADRTLLYQLDTQIQRLTAEKGGRDASVIALTGIYHNLLRRWADA
What are the official names of this protein?
PKHD-type hydroxylase BPSS1206.
Protein: HIS8_MYCSS
Sequence: MTVGERITLADLPLRDDLRGKSPYGAPQLQVPVRLNTNENPHPPSQALVDDVTRSVGEAAAELHRYPDRDAVALRSDLADYLNLRTGVELSVENLWAANGSNEVLQQLLQAFGGPGRSAIGFVPSYSMHPIIADATRTEWLQALRADDFGLDVDTAVREIAARRPDLVFVTSPNNPSGQSVPLEDLRRLLDAMETGILILDEAYGEFSSQPSGVALIDQYPTKLVVSRTMSKAFAFAGGRLGYLVAAPAVIEAMLLVRLPYHLSSLTQAAARAALRHADDTLASVATLIAERDRVANGLSQLGFRVVPSDANFILFGEFADAPATWRRYLDQGVLIRDVGIPGYLRTTIGLAEENDALLTASARLVETELAATLGAL
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: GATB_CULQU
Sequence: MSWNALFRRNLFIFNFRHRSFATKKAANPVARPNRWRSVIGLEVHAQIQSESKLFSGAEVSFGAPINACVALVDASIPGTLPVLNRRCVELGVRTALALGCEVAPVSAFDRKHYFYADLPAGYQITQQRAPLARGGLLTFPVFVPGVTKKPYYKSARVHQLQLEQDSGKSLHDPVERKSLVDLNRAGVPLMELVFEPDLETGEEAAALVKELILILTRLGSCSCRMEEGALRVDANISVHRENTPLGTRTEVKNIGSVRAVAQAIEYEIARQIDVLDGGGRIFNETRNWDAVERKTIAMRDKEVVQDYRFMPEPNLPPLHVHVEGDYCEGDDVVSAVKIRTDLPELPEETRKSIVETHHLTPEMAIILVNDITLHSHFRSILDEPGKTRSPKVVANFLINELLTILNKNKVDLEECHIPSSHLAEIVDMLETNRINQYLARLILQEALEQGASGQSPSQIAADRDWLMITDEAKIEQLCRDVIQRNPKVVEKYRSGKDKMLYALAGDIAKLTEQKADMARTVELLKRLLKK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NAR1_ASPOR
Sequence: MSAILSADDLNDFISPGVACIKPVETLPKNESSNSQNPYEVTTEDKVQPENLPPAQISLTDCLACSGCVTSAEAVLISLQSHAEVLNTLDAYPELPLTQNHNGPYTGSSDALDGESRIFVASVSPQVRASLAATYGISEKEATYMIDQFLSGPHGLRAGGKHGSGFSWVVDTNVMRDAILVLTADEVSETLKEPSARAISKDTLPKRPVLSSACPGWICYAEKTHPFVLPHLSRLKSPQALTGTFLKTVLSKALGVPPSRVWHLAIMPCFDKKLEASREELTDVSWSPLDGGVPLTESNKPVRDVDCVITTRELLTLASSRGISLPTLPLKSLAPSYTPHFPDETLNAFLFRKQNGSEQSMEAGTSGGYLHHVLKTFQAKNPGSEIVTQRGRNADVVEYSLMSPGGEPLMKAARYYGFRNIQNLVRKLKPARVSRLPGARVPAASAGGNRRQPISRNSASAGSGTDFAYVEVMACPGGCTNGGGQIRIEDAREASTSTQSVTAVENPSKPTPHEQRAWLARVDEAYFSAESDAEGEMDGQAQPLTIPEREARVHEAFEYWSNLMNIPLSKLVYTTYREVESDVGKPKDAPIDTTRVVELAGKIGGGW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor nar1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: HEMH_MANSM
Sequence: MKSSKTGILLANLGTPDTPSPKAISRYLKEFLSDPRVVDLPRWKWLPLLNGIILPIRSRRIAKNYGAIWTEQGSPLFAITQKQKALLTEFFQQRQQNVIIEIGMTYGNPSMQYAIDNLIEQKVDKIIVLPLYPQYSSTTTAPVFDVFAQALKRHRHIVPFEFIHSYHLDENYIEALVKSIKVRLKNDEFLLFSFHGIPKRYEQEGDFYRPQCEQTAQAVVQKLGLKKEQWRLCFQSRFGSEPWLQPYTDKFLETAAQQGITKLAVICPGFSADCLETLEEIKEENKRIFLAYGGESYHYIPALNDSPEHIACLGNLLLKRMTI
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAG_SALPK
Sequence: MSKVQSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKTGHQMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPQTCVDLWVGWGVPKERCIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDVRAVNYLFKTPGGNLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMAESLNTKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
What is the function of this protein?
Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P.  Is essential for L-ascorbate utilization under anaerobic conditions.
What are the official names of this protein?
Probable L-ascorbate-6-phosphate lactonase UlaG, L-ascorbate utilization protein G.
What is the protein family that this protein belongs to?
Belongs to the UlaG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAGB_HUMAN
Sequence: MEESDSEKTTEKENLGPRMDPPLGEPEGSLGWVLPNTAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPDAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR
What is the function of this protein?
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade (PubMed:18497260, PubMed:20381137, PubMed:24095279, PubMed:23723238).  Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form (PubMed:18497260, PubMed:20381137, PubMed:24095279, PubMed:23723238).  In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB (PubMed:18497260, PubMed:20381137, PubMed:23723238).  Involved in the RCC1/Ran-GTPase pathway (PubMed:9394008).
What are the official names of this protein?
Ras-related GTP-binding protein B, Rag B, RagB.
What is the protein family that this protein belongs to?
Belongs to the GTR/RAG GTP-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Lysosome.
Protein: MTNW_EXIS2
Sequence: MTYITATYQLGTTDQLPKRAEQIALGLTVGSWTDLNHLEQQQLESFKGQVVHTEEHDGKGYITIRYPEHNVSRDFSAILTTVFGKLSLDGQIKLTDLQLPASFTTDFPGAKFGIEGVRQLIQVHDRPLLMSIFKGVIGRDLTFLREQLEAQLAGGIDLVKDDEILYDNPLTPALDRARIGRDVLNAHYEKTGKRALYAITLSGSVFGLKDQTKRLIEAGATAFLLNTFTYGLDVLRELAADPDISVPIFNHPALSGALIASPEYGIAAPVLLGTLPRLAGADLTLFPSPYGNVALAKDLARGIAVEATRIGETKTILPVPSAGIHPGLVAQLVHDFGTDSVINAGGGVHGHPQGAAAGVLAFRQALDAALAGESLTSAATRQEELRVALDAWGITK
What is the function of this protein?
Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
What are the official names of this protein?
2,3-diketo-5-methylthiopentyl-1-phosphate enolase, DK-MTP-1-P enolase, RuBisCO-like protein, RLP.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: TSR1_MOUSE
Sequence: MAAHRSGPLKQQNKAHKGGRHHGGGSAQRDSKGRVGPKILCKKLKRQLSRIDQRHRASQLRKQKRESVLAEKRQLGSKDGPPHQVLVVPLHSRISLPEAFKLLQNEDLGTVYLSERGSTQSFMLLCPSLKHRWFFTYARPGDLHTLLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGLSGFPPKKQIDARKKLSKMVEKRFPEDKLLLLDTQQESGMLLRQLANQKQRHLAFRDRRAYLFAHVADFVPSEESDLVGTLKISGYVRGRTLNVNSLLHIVGHGDFQMNQIDAPVDPFPLNPRVIKSQKKPNMAMEVCVTDAAPDMEEDLKVLMKADPDHQESLQTEAIPDPMEGEQTWPTEEELDEADDLLKQRSRVVKKVPKGTSSYQAEWILDEGDESDGEGGEYDDIQHEGFMEEESQDGSGEEEEEECETMTLGESVRDDLYDEKVDAEDEERMLEKYKQERLEEMFPDEMDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPRDYARIFQFQNFVNTRKRIFKEIEEKEAEGAEVGWYVTLHVSDVPVSVVEYFRQGAPLIAFSLLPYEQKMSVLNMVVSRNPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKFQRFLTADAAFVVTVFAPITFPPASVLLFKQRRNGMHSLIATGHLFSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVMWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWVKSDISSTVSEVDME
What is the function of this protein?
Required during maturation of the 40S ribosomal subunit in the nucleolus.
What are the official names of this protein?
Pre-rRNA-processing protein TSR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.