PharMolix/UniProtQA huggingface dataset:
Protein: DRL11_ARATH
Sequence: MAGELISFGIQNLWNLLSQECELFQGVEDQVTELKRDLNLLSSFLKDADAKKHTSAVVKNCVEEIKEIIYDGEDTIETFVLEQNLGKTSGIKKSIRRLACIIPDRRRYALGIGGLSNRISKVIRDMQSFGVQQAIVDGGYKQPQGDKQREMRPRFSKDDDSDFVGLEANVKKLVGYLVDEANVQVVSITGMGGLGKTTLAKQVFNHEDVKHQFDGLSWVCVSQDFTRMNVWQKILRDLKPKEEEKKIMEMTQDTLQGELIRLLETSKSLIVLDDIWEKEDWELIKPIFPPTKGWKVLLTSRNESVAMRRNTSYINFKPECLTTEDSWTLFQRIALPMKDAAEFKIDEEKEELGKLMIKHCGGLPLAIRVLGGMLAEKYTSHDWRRLSENIGSHLVGGRTNFNDDNNNTCNYVLSLSFEELPSYLKHCFLYLAHFPDDYEINVKNLSYYWAAEGIFQPRHYDGEIIRDVGDVYIEELVRRNMVISERDVKTSRFETCHLHDMMREVCLLKAKEENFLQITSSRTSTGNSLSIVTSRRLVYQYPITLDVEKDINDPKLRSLVVVANTYMFWGGWSWMLLGSSFIRLELLRVLDIHRAKLKGGKLASSIGQLIHLRYLNLKHAEVTHIPYSLGNLKLLIYLNLVILVSGSTLVPNVLKEMQQLRYLALPKDMGRKTKLELSNLVKLETLKNFSTKNCSLEDLRGMVRLRTLTIELRKETSLETLAASIGGLKYLESLTITDLGSEMRTKEAGIVFDFVYLKTLTLKLYMPRLSKEQHFPSHLTTLYLQHCRLEEDPMPILEKLHQLKELELRRKSFSGKEMVCSSGGFPQLQKLSIKGLEEWEDWKVEESSMPVLHTLDIRDCRKLKQLPDEHLPSHLTSISLFFCCLEEDPMPTLERLVHLKELQLLFRSFSGRIMVCAGSGFPQLHKLKLSELDGLEEWIVEDGSMPQLHTLEIRRCPKLKKLPNGFPQLQNLELNELEEWEEWIVEDGSMPLLHTLRIWNCPKLKQLPDGLRFIYSLKNLTVPKRWKKRLSKGGEDYYKVQHIPSVEFY
What is the function of this protein?
Potential disease resistance protein.
What are the official names of this protein?
Probable disease resistance protein RF9.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: GATA_NATTJ
Sequence: MKLHELTLMEVKRGLEQGDFSSEELVTSVYDRIEETEDHIKAYITLTKEQALAQSKEIDSQRAKGEELGPLAGIPVAIKDNICTKDVTTSCASKILEDFVPPYNATVISKLAEAGAIIVGKTNMDEFAMGSSTENSAFFVTSNPWDTERVPGGSSGGSAASVASAQVPLALGSDTGGSIRQPASFCGVVGMKPTYGRVSRYGLVAFASSLDQIGPLSKNVEDTALALDIISGHDHMDSTSVDLEVPNHTDFLNQDIDELTIGIPKEYYELVDNDVKSLVESSLQSIEPEAGNYRQVSLPTTEHALSAYYLIAPAEASSNLARFDGVRYGQRFATDDLKTMYNQTRKEGFGNEVKQRVMLGTYALSAGYYDALYLKALKVRSLIKQEFEQVFSECDVLIAPTTPTVPFREGENVDDPLTMYKNDICTAPVNLAGLPSISIPCGFSNGLPVGLQVIGKAFDEGKVIQVAHKIEQMLQVFKNAPQQGLDNQGGK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: BSAZ_BURP1
Sequence: MAEKTEKPTAKKLRDAAKKGQTFKARDIVALIVIATGALAAPALVDLTRIAAEFVRIASTGAQPNPGAYAFAWAKLFLRIAAPFVLLCAAAGALPSLVQSRFTLAVESIRFDLTALDPVKGMKRLFSWRSAKDAVKALLYVGVFALTVRVFAGLYHADVFGLFRARPALLGHMWIVLTVRLVLLFLLCALPVLILDAAVEYFLYHRELKMDKHEVKQEYKESEGNHEIKSKRREIHQELLSEEIKANVEQSDFIVANPTHIAIGVYVNPDIVPIPFVSVRETNARALAVIRHAEACGVPVVRNVALARSIYRNSPRRYSFVSHDDIDGVMRVLIWLGEVEAANRGGPPPETRALTSAEPQARDGVAPPGDACADNAFPDDAPPGAAAPNAGSPDGPAPDGGAPARTGDQNA
What is the function of this protein?
Part of the bsa type III secretion system, is involved in the intracellular replication of invading bacteria inside the host cell.  Probably necessary for the lysis of the vacuole membrane and escape into the host cell cytoplasm (By similarity).
What are the official names of this protein?
Secretion apparatus protein BsaZ.
What is the protein family that this protein belongs to?
Belongs to the type III secretion exporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYA_SHIFL
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADIDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNLPIETNIMNLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS1_CAEEL
Sequence: MGYMGCWCSNLGRKYSGTVSPQRSVQPEALSYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSEYSDENILFWQACEELKREKNSEKMEEKARIIYEDFISILSPKEVSLDSKVREIVNTNMSRPTQNTFEDAQHQIYQLMARDSYPRFLTSIFYRETLASFGITEMDIGGDEEKEREQRAERARLNVPATAAEGSSKDISMV
What is the function of this protein?
Inhibits G protein signaling in nervous system, interacting preferentially with the G(O) subfamily member goa-1.  In vitro, protein acts as a GTPase activator of goa-1.  Rgs-1 and rgs-2 redundantly adjust signaling when worms are fed to allow rapid induction of egg-laying behavior.
What are the official names of this protein?
Regulator of G-protein signaling rgs-1.
Protein: RNT_HAEIE
Sequence: MSDSQEIPYHNQLKNRFRGYFPVIIDVETAGFDAKKDALLELAAITLKMDENGYLHPDQKCHFHIEPFEGANINPESLKFNGIDIHNPLRGAVSELDAITGLFQMIRRGQKDADCQRSIIVAHNAAFDQSFVMAAAERTGVKRNPFHPFGMFDTASLAGLMFGQTVLVKACLAAKIPFDGKQAHSALYDTERTAELFCYMVNHLKDLGGFPHISQIDETENTAENQTAL
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: CYB6_TRIV2
Sequence: MANVYDWFEERLEIQAIAEDVTSKYVPPHVNIFYCLGGITLVCFLIQFATGFAMTFYYKPTVAEAYSSVQYIMNEVNFGWLIRSIHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVSGVILAVITVSFGVTGYSLPWDQVGYWAVKIVSGVPEAIPVVGVLISDLLRGGSSVGQATLTRYYSAHTFVLPWLIAVFMLFHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CYSD_RHILO
Sequence: MTIALTHLQRLEAESIHIFREVAAAFAKPVMLYSVGKDSSVLMHLAMKAFYPAKPPFPFLHVDTTWKFREMIAFRDQMAQKLGFDLLVHVNEDGVRDNINPFDHGSNTHTHVMKTVALRQALDKYGFDAAFGGARRDEEKSRAKERIFSFRNAQHVWDPKNQRPEMWKIFNTRIASGESIRVFPLSNWTELDIWQYILQENIPIVPLYFAKERPVVERDGMLILKDDDRMKLRPGETVENRLVRFRTLGCYPLTGAIESDADTLEAIVGEMLTARTSERQGRLIDRDEAGSMEKKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: MURA_SERP5
Sequence: MDKFRVQGRTRLSGEVAISGAKNAALPILFAALLAEEPVELQNVPKLKDIDTTIKLLNQLGTKIERNGSVFVDASGVNEFCAPYDLVKTMRASIWALGPLVARFGRGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMSAATLATGTTVIENAAREPEIVDTANFLNTLGAKITGAGSDRITIEGVERLGGGVYRVLPDRIETGTFLIAAAVSGGKVMCRDTRPDTLDAVLAKLREAGADIEVGEDWISLDMHGKRPKAVTIRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICHGVEQLSGAQVMATDLRASASLVIAGCIADGVTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_LYSSC
Sequence: MTEKQQTFAEAMTALEEIVRQLEQGDVPLENAIDLYKQGMELSKFCHSKLQHAEEQLVSIVQETGETTAFDPLKGEN
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPSC_BACSU
Sequence: MPQQPEIQDIYPLSFMQEGMLFHSLYDEQSRAYFEQASFTIHGQLDLERFQKSMDAVFDRYDIFRTAFIYKNVAKPRQVVLKQRHCPIHIEDISHLNERDKEHCTEAFKEQDKSKGFDLQTDVLMRISILKWAPDHYVCIWSHHHILMDGWCLGIVIKDFLHIYQALGKGQLPDLPPVQPYGTYIKWLMQQDREEAAEYWKKRLQHFEKSTPLPKRTDQIPNGTLQQITFAIPEKETAELQKIAAASGATLNTVFQALWGIMLQKVNRSSDAVFGSVISGRPSELKDVENMVGLFINTIPIRAQSDSLSFSDLVRRMQKDMNEAEAYSYFPLYDIQAQSALKQELIDHIIVFENTPTQQEIEELNQAGSFDFSVKDFEMEEVTNYSCSVKVIPGRTLYVRIHFQTSAYQPSMMSEIKDYLLHMVSDVISDPSLPVSKMTLLDEDKTRKIVSQNNRTVSVSPEAPTLHGLFERQAAVTPERLAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLEVDMTSLECEEVKRHVSASVSDGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQHQFRLSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWEKDSALIVQAIHQENVTTAHFIPAMLNSFLDQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVARGYLNRPALTEERFLEDPFYLGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPGEIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLQRLLPGYMVPAYMIEMEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRIAKEFDVQVPLKDVFAHPTVEGLATVIREGTDSPYEAIKPAEKQETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNLERMDRAFKELIKRHESLRTAFEQDAGGDPVQRIHDEVPFTLQTTVLGARTEEEAAAAFIKPFDLSQAPLFRAQIVKVSDERHLLLVDMHHIISDGVSVNILIREFGELYNNRKLPALRIQYKDYAVWQEGFKTGDAYKTQGAYWLKQLEGELPVLDLPADHARPPMRSFAGDKVSFTLDQEVTSGLYKLARENGSTLYMVLLAAYTAFLSRLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRTRPEGGKPFVQYLQEVRETAMEAFEHQDYPFEELVDKLELTRDMSRNPLFDVMFVLQNMDQESLELDELCLKPAANNGHQTSKFDLTLYAQEQPRGLLTFQMEFSTDLYKKKTIEKWLQYFNNMLLSIIKDNKAALGTINILNEDEAHYLIHELNRTKIDYPRNETISRLFEMQAEQTPNAVAIVSDTQVFTYEDLNSWANQIASVLQIKGVGPDSVVALLTGRTPELIAGMLGILKAGGAYLPIDSNLPVERIAYMLSDSRAALLLQSEKTEKRLLGIECEQIIIEDIQKQGEAKNVESSAGPHSLAYIIYTSGSTGKPKGVMIEQRSVIRLVKNSNYITFTPEDRLLMTSSIGFDVGSFEIFGPLLNGAALHLSDQQTFLDSHQLKRYIEHQGITTIWLTSSLFNHLTEQNEQTFSQLKHLIIGGEALSPSHVNRIRNVCPEVSIWNGYGPTENTTFSTCLHIQKTYELSIPIGRPVGNSTAFILNQWGVLQPVGAVGELCVGGDGVARGYLGRPDLTKEKFVPHPFAPGDRLYRTGDLARWLSDGTIEYVGRIDDQVKVRGYRVELGEIETALRQIDGVKEAAVLARTAQTGSKELFGYISVKAGTNAEQVRSLLARSLPNYMIPAYIIEMETLPLTSNGKLNRKALPEPDVASKQTYIPPRNELEEQLALIWQEVLGIQRIGIEDSFFELGGDSIKALQVSARLGRYGLSLQVSDLFRHPKIKDLSPFIRKSERIIEQGPIQGDVPWTPVQQWFFSQDIEERHHFNQSVMLFHSGRLSENALRPALKKLAEHHDALRMVYRNDDRRWIQINQGIHESQLYSLRISDLSQSESGWETKIKQEVADLQQSINLQEGPLLHAALFKTLTGDYLFLAIHHLVVDGVSWRILLEDLSAGYQQAAAGQTIQLPPKTDSYQEYARRIQEYAQSSKLIREEAYWRSVEEQQAAELPYEIPHHVNIDFSKRDSLSFSLTEADTAVLLQNVNHAYGTDTQDILLTAASLAICEWTGGSKLRIAMEGHGREHILPELDISRTVGWFTSMYPALISFENHRDELGTSVKTVKDTLGRIPNKGVGYGMLKYLTHPENKSITFSKTPEISFNYLGQFNDIERQDTFRPSSLGSGKDITHTWKREQIIEMSAMAADKKLHFNLSYPPARFHRNTMEQLINRIEHFLLDIMKHCAGQQKAEKTLSDFSSQSLTAEDLDSISSLVEEL
What is the function of this protein?
This protein is a multifunctional enzyme, able to activate and polymerize the amino acids Glu and Ala/Val as part of the biosynthesis of the lipopeptide antibiotic plipastatin.  The Ala/Val residue is further epimerized to the D-isomer form.  The activation sites for these amino acids consist of individual domains.
What are the official names of this protein?
Plipastatin synthase subunit C, Peptide synthase 3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: ISPE_SACD2
Sequence: MLQTSLTLPAPAKLNLFLHITGRRPDGYHNLQTVFQLLDFGDELTFTPNQSGEITITPAIEGVPLEQNLVYKAANILRSHVNRPELGATIHLTKRLPMGGGIGGGSSDAATTLVGLNYLWQTGVSPTTLAQLGRQLGADVPVFVEGNSAWAEGIGEQLIALDLPQYWYVVLTPACHVSTVEIFSHKDLTRDTLAITVAAFFEKGGKNDCQPLVERLFPQVRDAVDWLNKFGPAKLTGTGASVFAAFPSKDAAQKVFANKPKHLNGFVAQGVNESPLHQRLPEQCITGV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: Y116_RICCN
Sequence: MIFNSTGKEKFIFSEPTKLKVVQKEFKTENGYKCGIVLEETIEASLTLRLNNKRIVRLKNLEA
What are the official names of this protein?
Uncharacterized protein RC0116.
Protein: GA2L1_MOUSE
Sequence: MANPVAGIAGSAAKSVRPFRSSEAYVEAMKEDLADWLNALYSLGLPGSGDGFLTGLATGTTLCQHANAVTEAARALAAARPTRGVAFQAHSVAPGSFMARDNVASFIGWCRAELGVPEVLMFETEDLVLRKNEKSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRATPQVSSVPAAEEDVTEIATVPGVPTRTPRMTPNDLRNLDELVREILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLEHYLDKHDPCRCSSSTHRLPQQRTGTFSPQRGSPTPSPRPGSPVPGSERRSSRPEVTPISLRGTKEGPETPLRPRDQLPPLPRSRRYSGDSDSSASSAQSGPMGARSDDSATGSRRERPSHRPTSCLPASPRRPTAPRSQSRDRLDRGRPRVAPGGRGAQLSTSSPARRTRSQSREEQAVLMVRRDRDGQHSWVARGRGGGGSGGSGRSTPQTPRALSPAAPRPSRGPSPGPELAATPASIFRTPLQLDPQQEQQLFRRLEEEFLANARALEAAASHTPMGSAPDPPAPDSAYCSSSSSSSSLSVLGGKCGQPGESGRTANGLPGPRSQALSSSSDEGSPYLAVGGALDATRSSLAGPEPSLTWARGRMDTQPDRKPSRIPTPRGPRRPSGPIELGAWHAQHSVTPRTEPDSSM
What is the function of this protein?
Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity).  Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity).
What are the official names of this protein?
GAS2-like protein 1, Growth arrest-specific protein 2-like 1.
What is the protein family that this protein belongs to?
Belongs to the GAS2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber. Note=Colocalizes with the tips of microtubule plus ends.
Protein: YIDD_STRCO
Sequence: MKYPLLALIKLYQWTISPLLGPVCKYYPSCSHYGYTAIDRHGAVKGTALTAWRILRCNPWSLGGVDHVPPRKRPRWHEMLRAAWRARKGGTSAAEPATEGRPAHPSSSDPSSPAAETSPHAQGA
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RUVA_JANSC
Sequence: MIGKLTGRLDYKGSDHALIDVGGVGYVVHCSDRTLAALPARGEVVALYTDLLVREDLLQLFGFLSPYEKEWHRLLTSVQGVGAKASMAILGTLGVEGAARAITLGDATAIKAAPGVGPKLAQRVVMELKDKAPAVMAMGGTLDDAMDDVVDDMPGESAAPAPAPQPRAPKRPASNAQAEALSALQNLGYGPSDAAQAVAQAAESASNTPELIRAALRLLAPKE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TRUA_LISMF
Sequence: MTRYKAIISYDGSGFYGYQVQPNTRTVQAEIEKALTKMHKGKTVRITASGRTDTGVHAKGQVIHFDSELDITAEKFQKALQVMTPFDISFLTVEEVPDDFHARFGTVGKEYRYVVKRTKIFDPFSRNFALHYPYELDISKMKLASKRLIGEHDFTSFCSARTERDSKVRTLYSIDFYEEDDETLVIAFQGNGFLYNMVRILTGTLLDAGQGRISPDDISEALLARDRQKLISKTAPPQGLYLWRVDYE
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: DNAA_SHEHH
Sequence: MAVSLWQQCIARLQDELSAQQFSMWIRPLQVEMEGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEQMGSDAPNLRFDIGSRPSARPIVQATAAIRTSRPVSREVVKPSFNTPHADPIANANHRSNINPTYQFDNFVEGKSNQLGKAAAMQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDKYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3603L_ASFP4
Sequence: MQPSTLQTLTKKALATQHVSKDDYYILERCGLWWHEAPISMYIDDDNQIIIKTLCYKEGIKLNTALVLAVKENNDDLIMLFTEWGANINYGLLFINNEHTRNLCRKLGAKEELETSEILRFFFETKHKITSSNIILCHELFSNNPFLQNVNMVDLRTIIYWELKDLTTNSMLNEIPFSEMLTKYWYGIAVKYNLKEAIQYFCQEYRHFDEWRLICALSFNNVFDLHEICNTTKVHMSINKMMELACMRDNNFLTIYYCFALGANVNRAMLISVKNFRIENMFFCMDLGANVIEHSKTLADIYGYSIIVNILSLKIYKANPILLSKETNPEKINTLLKNYYSKNMLAYDICCIDNYL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-3L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: AROC_LEGPC
Sequence: MSGNTFGALFTVTTFGESHGPAIGCVVDGCPPGMSLTEADIQPFLDKRKPGQSKYTTQRREEDKVQILSGVFDGKTTGAPIALLIQNTDQRSRDYEDIKNLFRPGHADFTYHYKYGHRDYRGGGRSSARETAARVAAGAIARLYLKRYLNLDIIGYLQQMGDLKLQFENENEINKNPFFCPNNKQIQELADYVDRLRRQGDSVGARVKILARGVPTGLGDPVFDKLDATLAYAMMSINAVKGVEIGAGFNAVEQLGSHHRDQMTAKGFLSNHAGGILGGIATGQPIEVSIALKPTSSITTPGQTINTEGEEVTVVTKGRHDPCVGIRAVPIAEAMMALVLMDHYLRHKAQCK
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: CH10_OCEIH
Sequence: MIKPLGDRVVIELVEQEETTASGIVLPDSAKEKPQEGKVVAVGSGRVENGEKIALEVSEGDRIIFSKFAGTEVKYEGTEYLILRENDILAIIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POXIN_NPVAC
Sequence: MELYNIKYAIDPTNKIVIEQVDNVDAFVHILEPGQEVFDETLSQYHQFPGVVSSIIFPQLVLNTIISVLSEDGSLLTLKLENTCFNFHVCNKRFVFGNLPAAVVNNETKQKLRIGAPIFAGKKLVSVVTAFHRVGENEWLLPVTGIREASQLSGHMKVLNGVRVEKWRPNMSVYGTVQLPYDKIKQHALEQENKTPNALESCVLFYKDSEIRITYNKGDYEIMHLRMPGPLIQPNTIYYS
What is the function of this protein?
Nuclease that cleaves host 2',3'-cGAMP.
What are the official names of this protein?
Poxin, Protein p26, p26.
What is the protein family that this protein belongs to?
Belongs to the poxin family.
Protein: DER_RICRO
Sequence: MTKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPGLDEHPNSMGERLIEQTTKAILEADLICFMVDARSGILPDDKLLSSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAKLPEEESIETNIADPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKKSTITESLEKLSASDTINSIKLANTVILMIDALAPLKQQDLNIASHVVNEGRSIVIVVNKWDLVKESEKEAFQEEFYYQINTHLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFTYVKTKNPYV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ACPS_ALKCK
Sequence: MIVGIGIDLIELKRIEAAFARQPRFPGRVLTSYEQDQMAQLAPNRQIEYLAGRFAAKEAFAKAKGTGIGAGLSWHDIEIRTEGSGKPYIVVNDDSARVHLSITHSKEYAAAQVVIET
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEDA_SULAC
Sequence: MLNPFQLLFYSQLLASLTYFIGAAIYALPVPVYGVKKWAPRLITDSIYVVVWNSIYLGVLLFLGELLSLLGVTWDGYFSWLNNILYIEQSLYLMVKTILTASNAVPEVSALIQVVPFGALLTVITSALTFTSTLIAVSKIVYQYVAVFIATGVLFLSIPFRIGRSVGGAFIGSGIVFYVGLPYLPQFLAAFQMLPTQELNTPPQNASAIIDYYVHVVPSIITSLVIGPVIYIFILVGFSMGVASLVSGYGSRLPLIIDVF
What is the function of this protein?
Part of the Ced system, which is involved in DNA import.
What are the official names of this protein?
DNA import protein CedA, Crenarchaeal system for exchange of DNA protein A.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYS_PSYA2
Sequence: MIDPKLLRGDLTDLQQQLATRGYTLDMAFWQSIENERKSLQVQTEELQSRRNAGAKQVGALKKSGEDTSELLADMQSVSGEIKTAEDELRTLQERINQAALQIPNIPAADVPVGASEDDNVEVRKWGTPREFDFEIKDHAHIGETLGMLDFEAAAKLTGSRFNVLKGQLAQMHRALIQFMLNTHTIKYGYTETYVPYIVNSESLKGTGQLPKFEGDLFKLINHTNNDDMDFYLIPTAEVPMTNLVRGERLDIKELPLKFTAHTPCFRSEAGSHGRDTRGLIRQHQFEKVEMVNIATAEQSDELLEAMTGQAEFILQQLNLPYRTVKLCTGDMGFAAQKTYDIEVWLPSQDTYREISSCSNCGDFQARRMGTRVKDGKQTSLVHTLNGSGLAVGRTLLAVMENYQNADGSITIPEVLRPFMGGADSIL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.