PharMolix/UniProtQA huggingface dataset:
Protein: REXO3_YARLI
Sequence: MQFSGEGLFFHSPFNSPKKHMFSSSKGLFRGHPCPSIAAGQFCRLLCCPFDHPERVKRESENGSDSAEMVKRRKLEVGQGVARVAGDSSGGKLELPGARQALNQRDRPEIEGVGASPKTEGGRAEGAEKKEFASSQSSQKEQQETPHASATPQASVSPQTSAPPQHVSSSVSEDVLKQGKNGITSKSEKSSVKQPGSRDIYQPSSSREPPVSSIDTRTSSSPKSALEAVMTTSASPSQSRDGSRNTSASPSSSRDAEHLMPTTIFPCPATVPQRIAYLKAIHSALTDKRKLKFPKRAAILEELAAAKRSAGNYMVYTNECRVLVKSIKDGSWRGGKAGGTKTDSKTSGHITSSISNQLDMLASKTKPLLAQNGYPVNPDPLKSGLPSNIGIQHCDRCDKAFDVPKVDNYGSCKYHWARARMGGNSTMPEKFYPCCNQPVGMSEGCEEAPRHVYKLHDLNDLAFVIPFRTVSTSESLDTSTSTSTSTSATTSAPSAKSTKTASRPASTPTKSLTSSLDLEKSRQPFNKARRPRTIFNGPAVNQREPDITLETMKRGIGESRGQADSQERSSEPRERSARVREQPSGSCDQAGSLQTSVVAVDCEMLYTSLGMELCRVTCIDYHGKKTLDRVVRPTGRILDYNTRFSGISDINEPIITESGEKGDSISFEEAHRLILKLINKQTILVGHGLENDLIAMRLIHDRIIDTSILYPDFNPRYKTALKTLALKYLKRTIQTGEHDSMEDALAALDVVKCHLKG
What is the function of this protein?
3' to 5' exoribonuclease required for proper 3' end maturation of MRP RNA and of the U5L snRNA.
What are the official names of this protein?
RNA exonuclease 3.
What is the protein family that this protein belongs to?
Belongs to the REXO1/REXO3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CMOA_SHEDO
Sequence: MNSKQDRIYAKPAQTISDFQFDSRVAGVFNDMIRRSVPGYNQIIATLGDFARRYVTPNSKVFDLGSSLGSATLSIRRQIEGRQCQIIAIDNSQSMIERCEENLAAYVSDTQVTLVCDDIRNVDINNASMVVLNFTLQFLPPEDRDTLIKRIYDGMLPGGILVLSEKVKFDDACIQTLLDEQHLDFKRANGYSELEISQKRSALENVMRTDTLVQHQQRITDSGFSHFSVWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: THMAC_HIRME
Sequence: GCFEDWSRCSPSTASATGVLWRSCDSYCKVCFKADRGECYDSPSLNCPHRLPNNKQCRCINARTAKDNRNPTCWA
What is the function of this protein?
Has a bactericial activity.
What are the official names of this protein?
Theromacin.
What is the protein family that this protein belongs to?
Belongs to the macin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL17_ERWT9
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRPEAQAEAVAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: ITLN1_XENLA
Sequence: MLSYSLLLLALAFPAGHAGSCEQASISEKKEKILNLLACWTEGNADNSLSRSGGSPTGDMNYGYRSCNEIKSSDSRAPDGIYTLATEDGESYQTFCDMTTNGGGWTLVASVHENNMFGKCTVGDRWSTQQGNMLQNPEGDGNWANYATFGLPEGATSDDYKNPGYYDIEAKNLALWHVPNKTPMVMWRNSSILRYRTQNGFLTEEGGNLFELYKKYPVKYDIGKCLADNGPAVPVVYDLGSAEKTASLYSPNGRSEFTPGFVQFRAVNSERATLALCAGVKVKGCNVEHHCIGGGGYIPEGSPRQCGDFAALDWDGYGTNLGWSASKQIIEAAVMLFYR
What is the function of this protein?
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner (PubMed:26755729).  Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf) and D-phosphoglycerol-modified glycans (PubMed:26755729).  Binds to S. pneumoniae serotypes with glycans that contain beta-linked D-galactofuranose (beta-Galf) and with D-phosphoglycerol-modified glycans (PubMed:26755729).  Can bind a variety of monosaccharides (in vitro) (PubMed:15537792).  Probably plays a role in the defense system against microorganisms (Probable).
What are the official names of this protein?
Intelectin-1, Embryonic epidermal lectin, Xeel.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle.
Protein: RIMM_LACJO
Sequence: MTEYFEVGKILSPHGLKGEVKVNATTDFPEERLATGSRLFIKNNKQYEELIVENTRRHKQFYLVKFEKIDDIDQAEKICSKELYVAETDQQELPEGSYYFKDILNCPVYDAETGEKLGVLENIETPGANDIWEIKPEKGKSFWIPNIESVVKKVDLANKRIEVTLLEGLRDEN
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C7254_GLYUR
Sequence: MDASSTPGAIWVVLTVILAAIPIWVCHMVNTLWLRPKRLERHLRAQGLHGDPYKLSLDNSKQTYMLKLQQEAQSKSIGLSKDDAAPRIFSLAHQTVHKYGKNSFAWEGTAPKVIITDPEQIKEVFNKIQDFPKPKLNPIAKYISIGLVQYEGDKWAKHRKIINPAFHLEKLKGMLPAFSHSCHEMISKWKGLLSSDGTCEVDVWPFLQNLTCDVISRTAFGSSYAEGAKIFELLKRQGYALMTARYARIPLWWLLPSTTKRRMKEIERGIRDSLEGIIRKREKALKSGKSTDDDLLGILLQSNHIENKGDENSKSAGMTTQEVMEECKLFYLAGQETTAALLAWTMVLLGKHPEWQARARQEVLQVFGNQNPNFEGLGRLKIVTMILYEVLRLYPPGIYLTRALRKDLKLGNLLLPAGVQVSVPILLIHHDEGIWGNDAKEFNPERFAEGIAKATKGQVCYFPFGWGPRICVGQNFALLEAKIVLSLLLQNFSFELSPTYAHVPTTVLTLQPKHGAPIILHKL
What is the function of this protein?
Involved in the biosynthesis of Glycyrrhetinic acid (GA), a natural product which exhibits anti-inflammatory activity (PubMed:31138208).  Involved in the biosynthesis of the triterpenoid saponin glycyrrhizin (PubMed:22128119).  Catalyzes three sequential oxidation steps at C-30 of 11-oxo-beta-amyrin (PubMed:22128119).  Also able to catalyze C-30 monohydroxylation of beta-amyrin to produce 30-hydroxy-beta-amyrin (PubMed:22128119).  May be also responsible for the oxidation at positions C-22 and C-29 in addition to C-30 (PubMed:22128119).
What are the official names of this protein?
11-oxo-beta-amyrin 30-oxidase, Cytochrome P450 72A154.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS15_PONAB
Sequence: MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PGP1_SACS2
Sequence: MIKLVLVDLDGTLTEDRESTRIDLDAIYAIRLLQKSGIKVSLVSGNSYPILRGLYTYLYLDGGFVAENGCIVFYKEKYRMCRQMEQSLVDEFKSLFKLRDTWQNEYRECDFGFVPAKITDEMINWAKERNLYIKSSGYAVHIAYNPAGKRIGVEKLLQLLGLKKEDVAAIGDSSTDIELFQQVGFKVAVGNADDELKDIADYITSNKSGKGVREFVDKLLKGEFDGIK
What is the function of this protein?
Catalyzes the dephosphorylation of 2-phosphoglycolate.
What are the official names of this protein?
Phosphoglycolate phosphatase 1, PGP 1, PGPase 1.
What is the protein family that this protein belongs to?
Belongs to the archaeal SPP-like hydrolase family.
Protein: S5A1_MOUSE
Sequence: MELDELCLLDALVYLEGFLAFVAFVGLQMVGSSYGRYSSQWSGRRVPARPAWFLQELPSMAWPLYECIRPAAARLGNLPNRVLLAMFLIHYVQRTLVFPVLIRGGKPTLLFTFVLAFLFCTLNGYLQSRYLSQFAVYAEDWVTHPCFLTGFALWLVGMVINIHSDHILRNLRKPGETGYKIPRGGLFEYVSSANYFGELVEWCGFALASWSLQGVVFALFTLCALFTRARQHHQWYLEKFEDYPKTRKILIPFLL
What is the function of this protein?
Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids.  It plays a central role in sexual differentiation and androgen physiology.
What are the official names of this protein?
3-oxo-5-alpha-steroid 4-dehydrogenase 1, SR type 1, Steroid 5-alpha-reductase 1, S5AR 1.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NUOB_XYLFA
Sequence: MGVIQAIDRLMTNPIPDGQVDDILRPQGESPLLQKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGAARLDLDRYGIVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGILQLQKKIWRTQTNAG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF1_PARDP
Sequence: MAKEEMLEFPGVVKELLPNATFRVELENGHEIIAHMAGKMRKNRIRVLAGDKVQVEMNTYDLTKGRINYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_PSEU2
Sequence: MPNITVTSLLAMKQKGEKITMLTCYDATFAHTASQAGVEVLLIGDSLGMVLQGHDSTLPVTTAETAYHVACVKRGNQGAMILADLPFMANATLEQTLINSATLMQAGAHMIKVEGAAWLAESIRLLAERGIPVCAHMGLTPQAVNVLGGYKVQGRLETQARQMRADAIALEQAGAAMILLECVPSELAEEITQAVKVPVIGIGAGSATDGQVLVLHDMLGLSITGRVPKFVKNFMTGQPDIQSAIRAYVTAVKDLSFPATEHGFSA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAD1_MOUSE
Sequence: MASRASELPPGSGRSVTAGIIIVGDEILKGHTQDTNTYFLCRTLRSLGVQVCRVSVVPDEVATIASEVNSFSRRFTHVLTAGGIGPTHDDVTFEAVAQAFGEELKPHPELQAAIKTLGGEGWEKLSMVPSSARLHYGTDPRTGHPFRFPLVSVRNVYLFPGIPELLRRVLEGLKGLFQNTAVQFHLKELYVAASEGSIAPILSEAQAHFGRRLSLGSYPDWSSNYFQVKLILDSEEKEPLEECLAYLTARLPQGSLVPYQPDAVEKAGEAVYKLAESGSCLGKKVAGALQTIETALAQYHLSQLCVGFNGGKDCTALLHLFHAAVQRKFPDVPKPLQILYIRSISPFPELEQFLQDTIKRYNLQVLEAEGNMKQALGELQEKHPQLEAVLMGTRRTDPYSCSLSHFSPTDPGWPSFMRINPLLDWTYRNIWEFLRQLFVPYCILYDRGYTSLGSRENTTQNPALKCLSPGGHPVYRPAYLLENEDEERNSRM
What is the function of this protein?
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FAD pyrophosphorylase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAMB1_HUMAN
Sequence: MGLLQLLAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCIVSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLDLEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVDDIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDNLLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFFIDNIPYSMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPGSRYVVLPRPVCFEKGTNYTVRLELPQYTSSDSDVESPYTLIDSLVLMPYCKSLDIFTVGGSGDGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFLEKAKALKISGVIGPYRETVDSVERKVSEIKDILAQSPAAEPLKNIGNLFEEAEKLIKDVTEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDSITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDELAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNAWQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEELRNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVILQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDIQGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVKQSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLLKDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTCL
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.  Involved in the organization of the laminar architecture of cerebral cortex.  It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons.  Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.
What are the official names of this protein?
Laminin subunit beta-1, Laminin B1 chain, Laminin-1 subunit beta, Laminin-10 subunit beta, Laminin-12 subunit beta, Laminin-2 subunit beta, Laminin-6 subunit beta, Laminin-8 subunit beta.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Protein: MTA1_HUMAN
Sequence: MAANMYRVGDYVYFENSSSNPYLIRRIEELNKTANGNVEAKVVCFYRRRDISSTLIALADKHATLSVCYKAGPGADNGEEGEIEEEMENPEMVDLPEKLKHQLRHRELFLSRQLESLPATHIRGKCSVTLLNETESLKSYLEREDFFFYSLVYDPQQKTLLADKGEIRVGNRYQADITDLLKEGEEDGRDQSRLETQVWEAHNPLTDKQIDQFLVVARSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNIYDISKAISALVPQGGPVLCRDEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEAESKLKQVYIPNYNKPNPNQISVNNVKAGVVNGTGAPGQSPGAGRACESCYTTQSYQWYSWGPPNMQCRLCASCWTYWKKYGGLKMPTRLDGERPGPNRSNMSPHGLPARSSGSPKFAMKTRQAFYLHTTKLTRIARRLCREILRPWHAARHPYLPINSAAIKAECTARLPEASQSPLVLKQAVRKPLEAVLRYLETHPRPPKPDPVKSVSSVLSSLTPAKVAPVINNGSPTILGKRSYEQHNGVDGNMKKRLLMPSRGLANHGQARHMGPSRNLLLNGKSYPTKVRLIRGGSLPPVKRRRMNWIDAPDDVFYMATEETRKIRKLLSSSETKRAARRPYKPIALRQSQALPPRPPPPAPVNDEPIVIED
What is the function of this protein?
Binds to ESR1 and sequesters it in the cytoplasm and enhances its non-genomic responses.
What are the official names of this protein?
Metastasis-associated protein MTA1.
What are the subcellular locations of this protein?
[Isoform Short]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform Long]: Nucleus. Nucleus envelope. Cytoplasm. Cytoplasm, cytoskeleton. Note=Associated with microtubules. Localization at the nuclear envelope is TPR-dependent.
Protein: Y2636_VIBC1
Sequence: MNIDVVHLLEQNPILLIFVVLAIGLAFGKIRFGKLQLGNSIGVLITSLVMGHLGFSFNAEALTIGFMLFIYCVGIEAGPNFFGIFFRDGKHYFILSMTVLVSAVGLTYFCSHYMGLDFGLSAGMMAGALTATPVLVGAQDALNSGLATIPRNMDFSLVLENLSVGYAMAYLVGLISMIMFAKLLPKLQKQNLSDSAQQIAQERGLGNSSQRKVYLPIIRAYRVGPELIDWTDGKNLRELGIYRQTGCYIERIRRNGILAHPDGDAILQEGDEIALVGFPDSHARLDPSFRNGKEVFDRNLLDLRIVEEEIVVKSDAIAGKRLSDLNLSEFGCFLNRVVRAQIEMPMDLDIVLAKGDVLQVSGEKSRVHGLAEKIGFISIHSQMADLLAFCSFFILGIMFGLVTMTFGQVSFSLGNAVGLLLSGITLGFLRANHPTFGYVPQGALNMVKDLGLMFFMVGIGLSAGGKIFEHLSQVGPQIIGLAFIVSVVPVVLAYLVGAYVLKMNSALLFGAIIGARTCAPAMDVVNEYAKSTIPALGYAGTYAIANILMTLAGTILIILS
What are the official names of this protein?
Putative transport protein VIBHAR_02636.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YLU4_CAEEL
Sequence: MGKKKFIENEDGTTEVQETESEAPKDKKEKKEYRLRTLGANIKTSKKSFKEQFFMNYEDGLKLIKKMRGKGKGGQLVQKVMPRHISLPYHMSGKAAMEEACDWIAQNTVGKYRKEYKGIVVAVGSVDLASAPRVISDQYAFHTDVAINQIVFIPKIGDQYEAKVKYVQEGLMVGVVMDMITIHIKQNDKTSEDQVAIDDKILVKYSGIRIKSSLCHLKGEYVKMIEKAEIKEEEEVEDEADEETDVKEKVKEEEDEDEDMEE
What are the official names of this protein?
Uncharacterized protein F10E9.4.
Protein: NOTUM_HUMAN
Sequence: MGRGVRVLLLLSLLHCAGGSEGRKTWRRRGQQPPPPPRTEAAPAAGQPVESFPLDFTAVEGNMDSFMAQVKSLAQSLYPCSAQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEKNEYAFMGALIIQEVVRELLGRGLSGAKVLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRSLHDSHKASKTPLKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQPQGLEPSELLGMLSNGS
What is the function of this protein?
Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins.  Serine palmitoleoylation of WNT proteins is required for efficient binding to frizzled receptors (PubMed:25731175).
What are the official names of this protein?
Palmitoleoyl-protein carboxylesterase NOTUM, hNOTUM.
What is the protein family that this protein belongs to?
Belongs to the pectinacetylesterase family. Notum subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THYX_MYCPA
Sequence: MAEIAPLRVQLIAKTDFLAPPDVPWSTDADGGPALVEFAGRACYQSWSKPNPKTATNAGYIKHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPENDSRVVVPPGLDDDPELQQILAAAADASRATYTELLARLEAKFADQPSAVLRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRRLADVAPAVFADFEIATLADGTEVATSPLATEA
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: GLUC2_HUSDA
Sequence: HSQDTFTNEYNKYLEAKHAQEFVQWLIKSKRRGGLT
What is the function of this protein?
Glucagon plays a key role in glucose metabolism and homeostasis.  Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).
What are the official names of this protein?
Glucagon-2, Glucagon-II.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRM1_EHV1
Sequence: MGSAQARQRLLAIFGQVQAYIFQVEMLKRCDPSALLPLVGSLKLNALTIRMLRRKLGGALIEQAQHQQTPLACALTMALEYAEVEGERVLRAVDDVNLAGPEGFFRATMRLDEPCEYHVRVHLDTYGGPIDAEVQFLHDAENFLKQLNYCHLITGFEAGLDALESVARFLTRTVGSGIVVPPELCDPTHPCSVCFEELCVTANQGEAVHRRLLECTCDHITRQMAVRVANIDIARHLPHALSVASERRAAAEAALRALEARRVQGHNGKSAGTEDPTQQVASRLLESHHVFKPASRCLYAVSELKFWLASTKHGDMGQPRAIDTFTENLETLDKQEKFFHLQAATVELALFGRTLDHFDRLFADQLLGLDVIDGMLVGSCAVSPDDHIEALIKACYTHHMSAPLLQRLTDPDTSNREALKQLLGRIGVDTDDGAGELGDALDVDLDNLGGAPPVNSTPCGEDALCRTVSEERPWDKLLERATADASQRRRMYAERLSKRSIASLGRCVREQRRELEKTLRVNVYGEVLLHTYVSSYNGFCARRGFCAAVSRAGTIIDNRSSTSAFDSHQFMKAALLRHPIDQSLMPSITHKFFELINGPVFDNAGHNFAQPPNTALYYSVENVGLLPHLKEELARFMITAAKGDWSISEFQRFYCFEGVTGVTATQRLAWKYIGELILAAAVFSSVFHCGEVRLLRADRTYPDSSGAQRCVSGIYITYEASCPLVAVLSAAPHGAIGAETVVIYDSDVFSLLYAVLQQLAPGSGAN
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: RBS_CUCSA
Sequence: MASSILSSAAVASVNSASPAQASMVAPFTGLKSSAGFPITRKNNVDITTLASNAGKVQCMKVWPPLGLRKFETLSYLPDMSNEQLSKECDYLLRNGWVPCVEFDIGSGFVYRENHRSPGFYDGRYWTMWKLPMFGCTDSSQVIQEIEEAKKEYPDAFIRVIGFDNVRQVQCISFIAYKPQVLLFLSSIC
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRA_HAEIN
Sequence: MDNQSLKTHYSVYELANLKLKTLPSAPKNIWEQAKRENWKSQKRQGRGGGLEYELASLPIEVQNELLLKTTPEQTAVALQKIEETRPLASNEVWQLWDEASAKAQEQAKIKLGTMFAVANLVESGVNVLDAFRLVCGKENAERLKNNEKLLSVGSLKNWWYRVKDAPRQDWLPLMLNNSGKSSKNVAEIDEAAWQFFKNFYYSREKPSLAHSYEVLKQAAQYNGWRIPSRSSLKRKMERDVPKTEEVFRREGQYALSRLYPSQVRTVAMLQAMEWINGDGYQHNVWVRFPDGEIKRPKTWLWQDVRTRKVLAARTDKSENTDTIRLSLLDVISRYGLPKHLTIDNTRAAANKKMTGGVKNRYRYQVNENEVQGIIPALGIELHWTSIQFGKGRGQAKPIERAFSHGGLGDYVDKHLLLRGAYAGANAYEKPDYDGKNGAEQPVDYATFLMALEQGIQQWNNVGNRLTEICAGKSSYAEAFERDWAVAEKRPISQSQMRLLLTLHEEVRLNQDGTFYLNAGKIGTNKNRYESLALIGTSHKRVVVRYDPANLHDKVWVYAXTGEYLAEAEITEKAGFGDQMAGREHNKAMRNWVKHTEKAAKERAKAEEMELSNYAPAVEFEERFLEMLPEPVKAPQTQAEEVEYEEVLDFNTVRKVPKAVEVEAEEISEFNRDWEKGLELLKKSKGR
What is the function of this protein?
This transposase is essential for integration, replication-transposition, and excision of Mu-like viral DNA.
What are the official names of this protein?
Mu-like prophage FluMu transposase A.
Protein: FAKD3_RAT
Sequence: MAFTLRRAFCHMSVFWMPGAVVALKIHPANNVQKAVRDCLRVWFCSLQPDLFRVRFYHAYCKSFHSENGNDLHPVGEPWFSQAQVWNQPEQTLKNEDEEMLSRRLNSFASFEEVLSFIHTLDTLPVTLASAALLRICEIGKRDDEQRLPKEVLENRVFQALCLRCERDPSHLTNAVLVTVLQSLVIDPQSSLVLSLVAECQRRLRRGSLEVHHLCVLGESLARLQGASCEILKLVICQLQSENLETFAPEDIVSVYRILQACPEEVDKHQTFLNTVNNFSLSIVSYLSPKSISHVLTALVALDQTHARPLLIKLGKSVVRYIPRFTNEELRQVLEAFVYFGHSDRFFTEALEQHVAAQCFSLDPAVASSVMEYCSRKRILSKPIFDVVAEIFVCQSEKFSPSQISELIEPFGKLNYLPPNAPALFRKVENVLFAHLRHFPPKMLLRLLHSCSLIERHPVNFMSKIFSPFFLQRLQGKESYLDRLSLAQMTQLFLTSVLECPFYKGPKLLPKYQVKSFLTPCCSLETPMDLHLYKSVVIGLIDLLGSRLYFASKVLTPYYYTIDVEIKLDEDGFVLPFTVDEDVHTRVALCIDGPQRFCLGSKHLLGKEAIKQRHLRLLGYQVVQVPYHELELLTSRLELVDYLQRKLFSQSSTVHW
What is the function of this protein?
Required for normal mitochondrial respiration.  Increases steady-state levels and half-lives of a subset of mature mitochondrial mRNAs MT-ND2, MT-ND3, MT-CYTB, MT-CO2, and MT-ATP8/6.  Promotes MT-CO1 mRNA translation and increases mitochondrial complex IV assembly and activity.
What are the official names of this protein?
FAST kinase domain-containing protein 3, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FAST kinase family.
What are the subcellular locations of this protein?
Mitochondrion.