PharMolix/UniProtQA huggingface dataset:
Protein: NOS3_RAT
Sequence: MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSQAPVPPSPTRPAPDHSPPLTRPPDGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQSRPTQGPSPTEQLLGQARDFINQYYNSIKRSGSQAHEQRLQEVEAEVVATGTYQLRESELVFGAKQAWRNAPRCVGRIQWGKLQVFDARDCRTAQEMFTYICNHIKYATNRGNLRSAITVFPQRYAGRGDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPELFTLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSSEIGMRDLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLYSYQLAKVTIVDHHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWKGSAAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFRKAFDPRVLCMDEYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYNSSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKAAARDIFSPKRSWKRQRYRLSTQAESLQLLPRLTHVHRRKMFQATILSVENLQSSKSTRATILVRLDTGSQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPSTEPVAVEQLEKGSPGGPPPGWVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEESSEQQELEALSQDPRRYEEWKWFRCPTLLEVLEQFPSVALPAPLILTQLPLLQPRYYSVSSAPSAHPGEIHLTVAVLAYRTQDGLGPLHYGVCSTWMSQLKAGDPVPCFIRGAPSFRLPPDPNLPCILVGPGTGIAPFRGFWQDRLHDIEIKGLQPAPMTLVFGCRCSQLDHLYRDEVLDAQQRGVFGQVLTAFSRDPGSPKTYVQDLLRTELAAEVHRVLCLEQGHMFVCGDVTMATSVLQTVQRILATEGSMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQLRGAVPWSFDPPTQETPGS
What is the function of this protein?
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway.  NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
What are the official names of this protein?
Nitric oxide synthase, endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, eNOS, NOS type III, NOSIII.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Cell membrane. Note=Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle, which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
Protein: Y2100_MYCTU
Sequence: MAGALFEPSFAAAHPAGLLRRPVTRTVVLSVAATSIAHMFEISLPDPTELCRSDDGALVAAIEDCARVEAAASARRLSAIAELTGRRTGADQRADWACDFWDCAAAEVAAALTISHGKASGQMHLSLALNRLPQVAALFLAGHLGARLFSIIAWRTYLVRDPHALSLLDAALAEHAGAWGPLSAPKLEKAIDSWIDRYDPGALRRSRISARTRDLCIGDPDEDAGTAALWGRLYATDAAMLDRRLTEMAHGVCEDDPRTLAQRRADALGALAAGADHLACGCGKPDCPSGAGNDERAAGVVIHVVADASALDAQPDPHLSGDEPPSRPLTPETTLFEALTPDPEPDPPATHAPAELITTGGGVVPAPLLAELIRGGATISQVRHPGDLAAEPHYRPSAKLAEFVRMRDLTCRFPGCDVPAEFCDIDHSAPWPLGPTHPSNLKCACRKHHLLKTFWTGWRDVQLPDGTVIWTAPNGHTYTTHPGSRIFFPTWHTTTAELPQTSTAAVNVDARGLMMPRRRRTRAAELAHRINAERALNDAYMAERNKPPSF
What are the official names of this protein?
Uncharacterized protein Rv2100.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv3776.
Protein: LOR5_ARATH
Sequence: MKGGLLVDDEFIHGEERSLTVRKTSLFFAGDGFTVYDCKGSLVFRVDSYGGPNTRDTDEVVLMDAHGRCLLTLRRKRPSLRRRWEGYLGERSDGQKPIFGVRRSSIIGRNSVTVEVYGDYQCSEYLIEGSFGARNCTVVEAETRRKVAEIRRKVDASTNVMLGKDVFSLNVKPGFDGAFAMGLVLVLDQIYGDDLLEVGEEQVHPSAEDL
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 5.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: SYS_STRR6
Sequence: MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVKVETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTTTLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTGARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTFELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTYDLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEALRPYMGGAEVIKP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_DINSH
Sequence: MPKRILNGVVTSDANAQTVTVSVERRFTHPVLKKTIRKSKKYRAHDAENAFKVGDKVRIQECAPMSKTKRWEVIAN
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CLCN5_HUMAN
Sequence: MAMWQGAMDNRGFQQGSFSSFQNSSSDEDLMDIPATAMDFSMRDDVPPLDREVGEDKSYNGGGIGSSNRIMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSEHVTFEERDKCPEWNSWSQLIISTDEGAFAYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENRFNTSKGGELPDRPAGVGVYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPDSILFN
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges chloride ions against protons (PubMed:20466723).  Important for normal acidification of the endosome lumen.  May play an important role in renal tubular function.  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons.  The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
What are the official names of this protein?
H(+)/Cl(-) exchange transporter 5, Chloride channel protein 5, ClC-5, Chloride transporter ClC-5.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: COPD_SCHPO
Sequence: MVVLAVSIVNRGGKAIISRQFREMSRVRVESLLSSFPALVSEKSQNTTVESDNVRFVYQPLDELYIVLITNLQSNILQDIDTLHLLSQVVTSICSSLEEREILEYAFEIFTAFDEATSLGYRDNVSLTQIKTYLEMESHEEKIQEIVSRNKEIEATEERKRRIKQLELQKKEAARRAAQNLPSADAYESIGYQTVNTTFATSNVEDESAMESYHAAAKASSAPKAKGMQLGKKKNTSLLY
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit delta, Delta-coat protein, Delta-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPOC1_SYNJB
Sequence: MAKTEQRFDYVKIGLASPERIMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCERIFGPAKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVTHVWYLKGIPSHIATLLDMPLRDVEQVVYFNAYVVVDPGNAQNLSYKQLLTEDQFLEIEDQMYEEGSELQLPENWAMIGAEAIERLLKDIDLEKEAEQLREEITSARGQKRARLIKRLRVIDNFIATGSRPEWMVLRVLPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEIMAPEIIVRNEKRMLQEAVDALIDNGRRGRVVAGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPNLRMHQCGLPKEMAIELFQPFVIHKLIKRGIVNNIKAAKKMIQSNDPQIWDVLEEVIDGHPVLLNRAPTLHRLGIQAFEPILVEGRAIQLHPLVCPAFNADFDGDQMAVHVPLSLEAQAEARLLMLATNNILSPATGAPIITPSQDMVLGCYYLTADNPHAPDIGDRFFASLEDALIAYDRGAIGLHSKVWVRYHGPMELGKGEKESEPQIIEEAGGIRLKITNYRRIREDQNGNVISQYIRTTPGRIIFNKTVQDILSA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: GCH4_PSEPG
Sequence: MTQLKLPDIAAQTQAYAVPLNWVGMCGIALPVQFEGRTAAAKVDAGVSLVDGSSRGIHMSRLYLALGSLEHQPLTPLAIRQLLEDFLSSHASLSSAAYLRFSFEHLLNRPALISPLAGWKSYAVTVDTRIENEVFHVELSVSVPYSSTCPCSAALARQLIQQQFQTHFSEQKIEKAAVLQWLGSAEGIVATPHSQRSTAQVQVRLNSNQQVLPITELIDRIEASLGTAVQTAVKRADEQAFALANGQNLMFCEDAARRLHQALRQIEWSKAFKLRVEHAESLHAHDAVATSQWQWDVSCAV
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: CH60_TREPA
Sequence: MAKQLLFNEEARKKLLSGVEQISSAVKVTLGPKGRNVLLEKGYGAPTVTKDGVSVAKEVELEDPFENMGAQLLKEVATKTNDVAGDGTTTATVLAYSMVREGLKAVAAGMTPLELKRGMDKAVAIAVDDIKQNSKGIKSNEEVAHVASVSANNDKEIGRILASAIEKVGNDGVIDVDEAQTMETVTEFVEGMQFDRGYISSYFVTDRDRMETVYENPYILIYDKSISTMKDLLPLLEKIAQTGRPLLIIAEDVEGEALATLVVNSLRGTLKTCAVKAPGFGDRRKEMLEDIAILSGGQVISEDLGLKLESADIALLGQAKSVKVDKENTTIIDGSGKSKDIKDRIEQIKKQIEASTSDYDSEKLKERLAKLSGGVAVIKIGAVTEVEMKEKKHRVEDALNATRAAIEEGIVAGGGLALIQAAAALEKADLSGLTPDEAVGFKIVRRALEEPIRQISENAGIDGAVVAEKAKEKRGIGFDASKMEWVDMIKVGIIDPAKVTRSALQNAASVSGLLLTTECAIAAIPEKSSSTPPAPDMGGMGGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60, Common antigen, CA, TP4 antigen, TP-4, TPN60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_STAAB
Sequence: MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTSANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MSHD_MYCLE
Sequence: MVLNWRFALSADEQRLVREIISAATEFDEVSPVGEQVLRELGYDRTEHLLVTDSRPYAPIIGYLNLSSPRDAGVAMAELVVHPRERRRGVGAAMVRAALAKTGGRNRFWAHGTLASARATASVLGLVPVRELVQMQRSLRTIPDPMVPDQLGVWVRTYVGTVDDAELLRVNNAAFAGHPEQGGWTATQLAERRSEPWFDPAGLFLAFGDSSSNQPGKLLGFHWTKVHAAHPGLGEVYVLGVDPSAQGRGLGQMLTSIGIASLAQRLVGPSAEPTVMLYVESDNVAAARTYERLGFTTYSVDTAYALARIDD
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: Y6147_DICDI
Sequence: MSYSNTSGYNFNNRNDSDNDEENNNSNNINNGNNRNNENNENNESLKRKFEESFDEDENNNNINTNNNSSNSNIQPPSKRQEINYNVNDISNDSSYHSDEEENSSDSDVSLNKTNNSTFENFKNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKEEEGENFIESRTVSSPEISNTYVITINGNKKEIELYGKDDTTYNSQSSVSLPPLVDNAPPHIHHIDFNNNNNNNNNNNNNNNNNNNNRGGRGGYRGGHRGGRGASNNYNRNQQWHPSDGTPPPQQQHQNRNNNQQWHPSDGTPSPQQQQQHQNRNNNQQWHPSDGTPPPSSSHQNRNNNNNQQWHPSDGGSPPPSHQNKYQNNPGYQKRNNNQQQWHPSDGTPPPSHQNRNNHQQQQWHPSDGTPPPSHQNRNNQPFNRNLSPNQNRYPQNQQKMQQQQQPHPSD
What are the official names of this protein?
Putative uncharacterized protein DDB_G0284695.
Protein: CLA1B_XENLA
Sequence: MEQGMDYWLGQIQQKDVGKRLQVGPDLIEYLLDRQKSIDLEQDQTLLDRMVDGLATSWVNSSNYKVALLGMDILSALVTRLQDRFRTQIGTVLPSLMDRLGDAKDSVRDQDQNLLIKIMEQASNPQYMWERMFSGFKHKNFRTREGVCLCLIATLNVYGANSLTLSKIVPHICNLLGDPNSQVRDAAINCLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGTMILSTTDKNFDDEDSVDGNRPSSASSSASSKAPQTARRGVSLGTGRRPGTSSAAPKTGGTAKEGAGALDEEDFIRAFEDAPTVQIYSSRDLEESLNKIREILSDDKHDWEQRISALKKIRSLLLAGAAEYDNFFQQLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAVMPTVFNLVPNSTKIMATSGVVTIRLIIRHTHVPRLIPIITSNCTSKSVAVRRRCYEFLDLLLQEWQTHSLERHVSVLAETIKKGIHDADSEARIVARKCYWGFHGHFSKEAEQLFHALESSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTVSRATSKSTTGSLQRSRSDIDVNAAATSKTKAASGASTAPFSSVAALPPGSYASLGRIRTRRQSSGSTTSTASTPADTRGRSRAKVVSQSQPGSRSSSPGKLLGSSYGGIATGPQRVPQMPSEKRSKIPRSQGCSRETSPSRTVLDRFGISQPGRIPSAMRVLSSSTDLEAAVADALLLGDSRNKMKPVRRRYEPYGMYSDDDANSDASSACSERSYSSKNGGIPHYLRQTEDVAEVLNHCASSNWSERKEGLVGLQNLLKSQRLLSRVELKRLCEIFTRMFADPHSKRVFSMFLETLVDFVIIHKDDLQDWLFILLTQLLKKMGADLLGSVQAKVQKALDVTRDSFPFDQQFNILMRFIVDQTQTPNLKVKVAILKYIESLARQMDPTDFVNSSETRLAVSRIITWTTEPKSSDVRKAAQVVLISLFELNTPEFTMLLGALPKTFQDGATKLLHNHLKNSSNSSMGSPSNTIGRTPSRHSSSRASPLTSPTNCSHGGLSPSMLDYDTENLNSDEIYSSLRGVTEAIEKFSFRSQVDLNEPVRRDGKKESEMGSCDAGMASPASDLRGGTDMVEGGRMALDNKTSLLNTQPPRAFTGPRGREYNPYAYSDSINSYDKTALKEAVFDDDMDQLRDVPIDHSDLVADLLKELSNHNERVEERKGALCELLKITREDNLAVWEEHFKTILLLLLETLGDKDHAIRALALRVLREILRNQPARFKNYAELTIMKTLEAHKDSHKEVVRAAEEAASTLAGSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERISKESLHQILPDIIPGLLQGYDNTESSVRKASVFCLVAVYSVIGEELKPYLAQLTGSKMKLLNLYIKRAQTTNSNSSSSSDVSTHS
What is the function of this protein?
Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules during anaphase.  Plays a crucial role in chromatin-induced microtubule formation.  May also act at microtubule minus ends.  May be involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN).
What are the official names of this protein?
CLIP-associating protein 1-B, Cytoplasmic linker-associated protein 1-B, Protein Orbit homolog, Xorbit, Xorbit/CLASP.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Golgi apparatus, trans-Golgi network. Note=Localizes to microtubule plus ends. Associates with spindle microtubules, spindle poles, and kinetochores during metaphase, and shifts to the central spindle in late anaphase.
Protein: PTMS_MOUSE
Sequence: MSEKSVEAAAELSAKDLKEKKDKVEEKAGRKERKKEVVEEEENGAEEEEEETAEDGEDDDEGDEEDEEEEEEDEGPVRKRTAEEEDEADPKRQKTENGASA
What is the function of this protein?
Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections.
What are the official names of this protein?
Parathymosin.
What is the protein family that this protein belongs to?
Belongs to the pro/parathymosin family.
Protein: RS13_PROM5
Sequence: MARIAGIDIPREKRVEIALTYIYGIGLTRSKLILSNTGVNPDIRVKDLSDSDVQKLRVAAEDFTVEGDLRRQEGMALKRLQDIGCVRGRRHRMSLPVRGQRTRTNARTRRGSRKTVAGRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CHIA_BOVIN
Sequence: MAKLIFLTGLAFLLNAQLGSAYQLVCYFSNWAQYRPGLGSFKPDNIDPCLCTHLIYAFAGMSNSEITTIEWNDVALYSSFNDLKKKNSQLKILLAIGGWNFGTAPFTAMVATPENRKTFISSVIKFLHQYGFDGLDFDWEYPGFRGSPSQDKHLFTVLVQETREAFEQEAKQTNKPRLLVTAAVAAGISNIQAGYEIPQLSQYLDFIHVMTYDFHGSWEGYTGENSPLYKYPTDTGSNTYLNVEYAMNYWKKNGAPAEKLIIGFPAYGHNFILRDASNNGIGAPTSGAGPAGPYTREAGFWAYYEICAFLKDGATEAWDDSQNVPYAYKGTEWVGYDNVNSFRIKAQWLKENNFGGAMVWAIDLDDFTGTFCNQGKFPLINTLKDALGLKSATCNASTQSSEPNSSPGNESGSGNKSSSSEGRGYCAGKADGLYPVADNRNAFWNCVNGITYKQNCLTGLVFDTSCHCCNWA
What is the function of this protein?
Degrades chitin and chitotriose.  May participate in the defense against nematodes, fungi and other pathogens.  Plays a role in T-helper cell type 2 (Th2) immune response.  Contributes to the response to IL-13 and inflammation in response to IL-13.  Stimulates chemokine production by pulmonary epithelial cells.  Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1.  Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding (By similarity).
What are the official names of this protein?
Acidic mammalian chitinase, AMCase, Chitin-binding protein b04, CBPb04.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted.
Protein: T23O_BOVIN
Sequence: MSGCPFLGKSFGYAFKPLSAQGSEEDKSQAGVNRASKGGLIYGNYLQLEKVLNAQELQSEMKGNKIHDEHLFIITHQAYELWFKQILWELDSVREIFQNGHVRDERNMLKVITRMHRVVVILKLLVQQFSVLETMTALDFNDFREYLSPASGFQSLQFRLLENKIGVLQSLRVPYNRRHYRDNFRGKDNELLLKSEQERTLLQLVEAWLERTPGLEPHGFNFWGKLEKNIVKGLEEEFTKIQAKEESEEKEEQMAEFQKQKEVLLSLFDEKRHEHLLSKGERRLSYKALQGALMIYFYREEPRFQVPFQLLTFLMDVDSLMTKWRYNHVCLVHRMLGSKAGTGGSSGYQYLRSTVSDRYKVFVDLFNLSTYLVPRHWIPKMNPVIHKFLYTAEYCDSSYFSSDESD
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: Y1358_VIBVY
Sequence: MAASCPCGSNRTYALCCEIAHKHHANVITPEQLMRSRYSAHVLGLVDYVVNTYHPSCHAEEQREGIAESIENDWCKLEVVKAEAGSNENEGFVEFNAYFDEDGKRYCMTERSRFVKEDGLWYYIDGTFPEEEPEQDPRLNQSVSSLKVGRNDPCICGSGKKFKKCCG
What are the official names of this protein?
UPF0225 protein VV1358.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: RL24_CALMQ
Sequence: MPVLTSSSQPRKQHKALTKAPWHARRRLLTAPLSKDLQRQLGIRRIPVRVGDTVLILRGDFKGTRGKVTRVDYKRVRIYVDSASFKKPSGEAVYYPIHPSKVVIVELDQSDKARVAAIDKTRKAREAKAGVREVITPQQGGQS
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RLMH_PSEFS
Sequence: MRLRLIAVGSRMPKWVEEGWHEYAKRLPAELSLELVEIPLNTRGKNADVARFIRQEGEAMLAKVGPNERIVTLEVHGKPWSTEQLAVELDRWRLDSRTVNFMVGGPEGLAPEVCARADQRWSLSALTLPHPLVRILIGEQLYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB1_NOSS1
Sequence: MNPVAPTRKVKPPRNRPSDRRQARKKARIKTKGIYLRAIKDAFVKLNPKSAIKNPVMFVVWVATLVTLAVTINPDLFGPNQQKNPQLFNGLLTGILFFTVWFANFAEAVAEGRGKAQADTLRSTKSEAIAKQLSPDGTIAEVPSTNLKQGDTVYVVAGDIIPADGEVIMGVASVDESAITGESAPVLKESGSDVASSVTGGTRIISDELIVRVTSDPGKGFIDRMIALVEGAERSKTPNEVALTVLLAVLSLVFLFVIATLPAFAYYADTPVNVPTLIALLVALIPTTIGGLLSAIGIAGMDRVAQFNVIATSGRAVEVCGDINTLVLDKTGTITLGNRLAEEFIPINGYSVEQLASVAWAASVFDDTPEGKSIVRLAEKLGIRYDLDPNLAQAVEFSAKTRMSGTNLPGGREARKGAVGAIQGFVRSRNGQTIPELDAAYERVSQQGGTPLAVCLDNEIYGVIYLKDIVKSGIRERFDQLRRMGVRTIMLTGDNHITASVIAQEAGVDDFIAEATPEDKISVIQREQAQGKLVAMTGDGTNDAPALAQANVGVAMNTGTQAAKEAANMVDLDSDPTKLIDIVSIGKQLLITRGALTTFSIANDIAKYFAIIPVIFAAANLQSLNIMNLTSTNSAVLSALIYNALIIPALIPLALKGVQFRPLTANQLLQRNILIYGLGGVIAPFIAIKLIDILITLVGLA
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit 1, ATP phosphohydrolase [potassium-transporting] B chain 1, Potassium-binding and translocating subunit B 1, Potassium-translocating ATPase B chain 1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSIA_SHIFL
Sequence: MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSRDVIELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQTILSRYSHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQEPPIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKDAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGSRCAVFENPQHPYTRKLLAAVPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutathione import ATP-binding protein GsiA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SPEE_CLOAB
Sequence: MLDLWYSESHADDTKFSIRVKEHLYSEKTPFQQIDFFKSETFGTFFTLDGYIMMTEKDEFIYHEMITHVPMAVNPKIKKVLIVGGGDGGTSREILRYNTIEKVDMVEIDERVVRLCQKYLTQTSCKLDNDSRLTMHFEDGKEFVKRAETGFYDLILVDSTDPIGPGEGLFTNEFYRDCERILSDDGILINQHESPYYKDYCHEMKRAHSKIKDKFPISMVYQFHMPTYASGHWLFGFASKKYHPLNNLNADSWNSLGLKTKYYNTNLHKGAFALPNYVIDELEKTE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGOD_VARPS
Sequence: MKITRLHTYRVAPRWMFLKIETDEGISGWGEPVIEGRARTVEAAVHEFGETLIGKDPARINDLWQTMYRSNFYRGGAILMSAIAGIDQALWDIKGKALGVPVYELLGGRVRDRMKVYSWVGGDRPADIVQDMQRLLEGGIDTFKLNGCEEMALLDSPRAVDAAVAKVAAVRDALDMRVDFGLDFHGRVAAPMAKPLLRALEPLRPLFVEEPVLAEQAEHYPRLAASTSIPLAAGERMYSRFEFKRVLEEGGLAILQPDLSHAGGITECHKIAAMAEAYDVAFAPHCPLGPVALAACLQVDFVAHNAVLQEQSMGIHYNRGAELLDYVINKDDFRIDAGFIRALPKPGLGVEVDEERIVHASRNPPDWRNPVWRHADGSVAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.