PharMolix/UniProtQA huggingface dataset:
Protein: AP2A_DROME
Sequence: MAPVRGDGMRGLAVFISDIRNCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKSPAPLTSAAQNNALVNNSHSKLNNSNANTDLLGLSTPPSNNIGSGSNSNSTLIDVLGDMYGSNSNNNSSAVYNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPLTNFNPVLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLTAECIEDYADAPTIEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQPLDLPGARNKLMGFGMQLLDQVDPNPDNMVCAGIIHTQSQQVGCLMRLEPNKQAQMFRLTVRASKETVTREICDLLTDQF
What is the function of this protein?
Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  AP-2alpha is a subunit of the plasma membrane adapter.
What are the official names of this protein?
AP-2 complex subunit alpha, Alpha-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
Protein: USTM_USTVR
Sequence: MDMLQFFRDALVQETGRHVDNDDFDALFSELGADPLVGVAVIERVTNKTVEKAPRAARPPREAPLPRGNVRNAFQDACSHVQEFLRKAGSANFWSRVYPAQRQLVLAFVNDAFDRLGCSLADMPVGTIVTYPRGVLDKHRRVFDGAIFEILADGGLVNVDPELGAIRTSTVVDKTPPQQILATIILEHPQFANLHRLLNVTGSQFAECLTGRLDPIKLLFGRSKDLLQDFYTNAPMSLAASLHLVAVIKRLLADGEYRPGKSIDILEVGAGLGGTTRFVVEALIEAQVPFRYVYTDISASFFAASKNRYKSLPPGSSMEFLVLDVEIPPPETLLGGFDVVVSTNCIHATRNLGVSCSNVRKLLRGGGFFALIEFTSRMYWLDLVFGLLDGWWLFEDGRKHCTVDETVWEEKLQLSGFSDVLWADVEGDDKSSLQLLVACTD
What is the function of this protein?
Polyketide methyltransferase; part of the gene cluster that mediates the biosynthesis of ustilaginoidins, dimeric gamma-naphthopyrones isolated from different fungal species (PubMed:31050129).  The first step in the biosynthesis of ustilaginoidins is the production of gamma-naphthopyrone precursor YWA1 by the non-reducing polyketide synthase ustP, via condensation of one acetyl-CoA starter unit with 6 malonyl-CoA units (PubMed:31050129).  YWA1 is then probably substrate of the ustZ to yield norrubrofusarin via a dehydration reaction (Probable).  A key enzyme in the biosynthetic pathway is the laccase ustL, which catalyzes the oxidative dimerization of norrubrofusarin to ustilaginoidin A (PubMed:31050129).  It can produce the M- and P-atropisomers in varying amounts, depending on the reaction conditions (PubMed:31050129).  For the biosynthesis of 3-methylustilaginoid in derivatives such as chaetochromin A, a methylated derivative of YWA1 is required (Probable).  The C-methylation is considered to be catalyzed by ustM, the phosphopantetheine attachment site of which indicates that it acts on the growing polyketide chain before release of the product (Probable).  For the biosynthesis of chaetochromin A, it is assumed that saturation of the D2 double bond takes place before dimerization, and is probably catalyzed by an external reductase because no candidate gene was identified within the cluster (Probable).
What are the official names of this protein?
Polyketide methyltransferase ustM, Ustilaginoidins biosynthesis cluster protein M.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: PDXY_SALCH
Sequence: MKNILAIQSHVVFGHAGNSAAEFPMRRLGANVWPLNTVQFSNHTQYGKWTGCVMPPSHLTEIVQGIADIGQLAHCDAVLSGYLGSAEQGEHILGIVRQVKAANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRYALPASDIIAPNLIELEILSKHSVNNVDDAVQAARELIAQGPEIVLVKHLARAGYSSERFEMLLVTAQEAWHISRPLVDFGSRQPVGVGDVTSGLLLVKLLQGATLQQALEHVTAAVYEIMIATKTMQEYELQVVAAQDRIANPEHYFSATRL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: RIMB2_RAT
Sequence: MREAAERRQQLELEHEQALAILNAKQQEIQLLQQSKVRELEEKCRVQSEQFNLLSRDLEKFRQHAGSIDLLGSNSVALLDVPLAPGKPFSQYMNGLATSIHKGHEGPTGHYSVIGDYIPLSGDKLESPCVKPSFLLRSSSPRCRFESEMDDDRSSNKSKHSSSGKVHLCVARYSYNPFDGPNENPEAELPLTAGKYLYVYGDMDEDGFYEGELLDGQRGLVPSNFVDFIQDNESRFAGTLGSEQDQNFLNHSGISLERDSILHLHSPTQVDSGITDNGGGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGNSDELQCTLLVGKDVVVAPSQLRVDNITQISAQLSWLPTNSNYSHIIFLNEEELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQREKDEACVEFSTLPAGPPAPPQDVTVQAGATTASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVAEVIAPTANGAAVELVRLRSLEAKAVSVRTLSAQGESMDSALAAIPPDLLVPPAPHPRTAPPPKPLTSDMDTKDLGPHVKVDESWEQSRPPGPAHGHMLEPPDMHSTGPGRRSPSPSRILPQPQGAPVSTTVAKAMAREAAQRVAETSKLEKRSLFLEQSSAGPYANSDEEDGYASPEVKRRGTSVDDFLKGSELGQQPHCCHGDEYHTESSRGSDLSDIMEEDEEELYSEMQLEDGGRRRPSGTSHNALKILGNSALMGRGDRMEHVSRRYSHSGGGPQRHRPMAPSIDEYTGRDHLSPDFYDESETDPGAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIHADDEEMMDQLLRQGFLPLNTPVEKIERSRRSGRGHSVPTRRMVALYDYDPRESSPNVDVEAELLFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVHLSDAPPHYSHDPPMRTKAKRVSQPP
What is the function of this protein?
Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.
What are the official names of this protein?
RIMS-binding protein 2, RIM-BP2.
What is the protein family that this protein belongs to?
Belongs to the RIMBP family.
What are the subcellular locations of this protein?
Cell membrane. Synapse. Note=Synaptic plasma membrane.
Protein: CCA14_ORYSJ
Sequence: MSKEDAMSTGDSTESLDIDCLDDGDSEVVSSLQHLADDKLHISDNRDVAGVASKWTKHGCNSVEIDYIVDIDNNHEDPQLCATLAFDIYKHLRVAETKKRPSTDFVETIQKNIDTSMRAVLIDWLVEVTEEYRLVPETLYLTVNYIDRYLSSKVINRRKMQLLGVACLLIASKYEEICPPQVEELCYISDNTYTKDEVLKMEASVLKYLKFEMTAPTTKCFLRRFLRAAQVCHEAPVLHLEFLANYIAELSLLEYSLICYVPSLIAASSIFLAKFILKPTENPWNSTLSFYTQYKPSDLCNCAKGLHRLFLVGPGGNLRAVREKYSQHKYKFVAKKYSPPSIPAEFFEDPSSYKPD
What are the official names of this protein?
Cyclin-A1-4, G2/mitotic-specific cyclin-A1-4, CycA1;4.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: Y635_METJA
Sequence: MKFMRIVRILAILLALIIGTSLCGCLNDSKSEADELIKMLPVDYNGFVYVNFKNIEDSKYSSEYRSKILNALRLGNANGEKTGIYINKTKRMIFSGSGYDRFVIIIEGDYDFDKFKNHLKEIGVNPVEEYGGFKIYTKPNDDKIALTFYKDMIIAGTKQGVYDCINVINGEMDSLLKNREVMEIYDRLPSDACVYEVSGTYSPWYKTVAEGMSISFENNDRVKVVRVEKYKDEETAKEKYEELLKKKDRDKEEMEKKGITADIKLDGQYLIVTVEGPEDELKI
What are the official names of this protein?
Uncharacterized protein MJ0635.
Protein: GCH1_LYSSC
Sequence: MSNIDLLKIEEAVKMILEAVGEDVNREGLLDTPKRVAKMYAEMFSGLHEDAKDYFRTVFHEDHEELVLVKDIPFYSMCEHHLVPFYGKAHVAYIPNDGIVAGLSKLGRAVETIARRPQLQERITSSVADTIMEMLAPKGVYVVIEAEHMCMTMRGLKKPGSKTVTSVARGVYEEDEVKRREVLSFIQMS
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: YIBG_ECOLI
Sequence: MKACLLLFFYFSFICQLHGADVKIKQNESMMGSTAMTYDLSEEKLMKLKYKSQHGDSEASFRLYQYYCFTKNNIYKQLRFLERSASQGNVTAQFNYGVFLSDTNPTLSEYYNLNRAIYWMEFAVNNGNIDAKSKLQELKKLKRMDRRKNKENP
What are the official names of this protein?
Uncharacterized protein YibG, ORF-A3.
Protein: DCD_WOLWR
Sequence: MAVMPDKWIREKAENFGMIEPFVNHKSSKGVISFGLSSYGYDARVDNKFKIFTNVNSAIVDPKNFSENSFIDKETDVCIIPPNSFVLASTVEYFRIPRNVLVICVGKSTYARCGIIVNVTPLEPGWEGHVTLEFSNTTPLPAKIYANEGACQFVFLSGESECEKSYDDMKGKYMNQHGITLPLVK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: IF2_AZOSB
Sequence: MEQMSVTQFAGELKMPAAALLEQLKRAGVDKSSAADLLTEQDKSRLLEYLRRAHGGGEPKGKITLTRKQTTEIRATDSTGRARTVQVEVRKKRTFVKRDELLGDAASAESPLLEEELSVAGEAAGEAVAAPEPVLEAAPVEVVAEPEPVQPEPLPEPEPEPVVVEEAPVQQAAEPEPVEAAAVAAEAESPESAQPAAPRARPVSITELLSEEEIAAREREARRHRELVERQQADLRARQQREAAAKAAAEARRLDEEAKARAEQQKKEEAAKPAAKPAPGPTGTLHRPAKADDKAGKDAKRGPAREADGAKRRGIKTRGEVGGAASGNAWRGAKGGGRHGRQQDDRQTFQAPTEPIVREVHVPETITVADLAHKMSVKATEVIKTLMKMGSMVTINQVLDQETAMIVVEELGHKALAAKLDDPDAFLEETDAHKDAELLPRAPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVITFLDTPGHEAFTAMRARGAKATDIVILVCAADDGVMPQTREAIHHAKAAGVPVVVAITKIDKPEANAERVKQELVSESVIPEEYGGDTMFVPVSAKTGTGVDELLEAVLLQAEVLELTAAVDAPAKGLIVEARLDKGRGPVASLLVQSGTLRKGDVLLVGATFGRIRAMLDENGKPVDEAGPSIPVEILGLSDVPAAGDEAIVLGDEKKAREIALFRQGKFRDVKLAKQQAAKLESMFEQMAEGEVKSLPLIIKADVQGSQEALAQSLAKLSNDEVRVNVIHGAVGAISESDVNLAQASGAVIIGFNTRADAGARKLAESFGVDIRYYNIIYDAVDEVKSALSGMLAPEKREEVIGMVEIRQVFTISKVGSVAGCYVLEGLVKRGSSVRLIRNHTVVWTGELESLKRFKDDVKEVKFGYECGLQLKNYNDIQVGDQLEVFEIKEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BUCAT
Sequence: MGQKVHPNGMRLGIIKKWNSVWFANTKDFADHLDSDYKVRQFLMKTLEKASISRIIIERPAKSIRVTIYTARPGIVIGKKGEDVEKLRISIAKITGVPVQINISEVRKPELDAKLVSDSITSQLERRVMFRRAMKRSVQNAMRQGAKGIKVEVSGRLGGAEIARREWYREGRVPLHTLRANIDYSISEAHTTYGVIGVKVWIFKGEILGGMETVERLDKPSVQTKKQYRKNRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: METXA_MYCA1
Sequence: MTIPDVPTQTLPDEGEIGFVHIGSLTTEAGAVIDDVHIAVQRWGELSPTRDNVVVVLHALTGDSHVTGPAGPGHPTGGWWDEMVGPGAPIDTDRWCAVATNVLGGCRGSTGPSSRTRDGKPWGSRFPRISIRDQVEADIAALAALGIDEVAAVVGGSMGGARALEWIVGHPSRVRAGLLLAVGARATADQIGTQCTQIAAIKSDPNWQGGDYHDTGRTPDAGLAIARRFAHLTYRGEVELDTRFGNDAQLDEDPANGGRYAVQSYLEYQGVKLVERFDAGSYVVLTEALNSHDVGRARGGVRKALRSCPVPVVVGGITSDRLYPLRLQQELAEQLPGCAELQVVDSICGHDGFLVESEAVGEMIRKTLLLAGSQSAGPGGAGPGSRKGTTRR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_STRZT
Sequence: MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYGRGGRMKIENDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRKITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANHVVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVVETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEILWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RL10_SYNR3
Sequence: MGRTLENKQQIVEELKQLLGEAEMALVLDYKGLSIKEMSDLRGRLAANGICKVTKNTLMRRAIDGNDTWSDLDPLLTGTNAFVLVKGDVGGAVKAVQSFQKDSKKSELKGGLFEGRLLSQNDIKAIGDLPSKEGLMAQIAGSINAVATKLAVGVNEVPSGLARALQQHADSENS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MURE_PARMW
Sequence: MGQSLHALLRDVGLELPAGLADPQLTSITSDSRLVGEGSLFLGLPGERFDGGRFWRQALEAGAAAAVIGPSAAQELPPAADQPVLVLREPVARSIGELAASYWGHPCRRMALIGVTGTNGKTTTTHLIEHLAVRVGQPTALFGTLVNRWPGYSITATHTTSVADRLQAQLAEAASAGSQLAAMEVSSHALVQERVAGCRFAGAVFTNLTQDHLDYHGTMESYYEAKARLFTAPLLDGDGPSAVVNGDDPWGSRLAEQLGGRCWRSSLGDPQAELQMVDLEMTGQGVRGRLLSPAGSGAFCSPLLGRFNLMNLLQAVGVLLQRGLPLAPLLEAVGSFRGVPGRMERVVVNGAESAALPTVLVDYAHTPDGLENALAASRPFTDGRLVCVFGCGGDRDRGKRPQMAAIAARLADRVVVTSDNPRTEDPDQIIADVVAGMPSGTDLSVERDRATAIAEAIADASAADLVLIAGKGHEDYQILGTEKVHFDDREEAEQALRQRQ
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_CLONN
Sequence: MIKITLKDGKVLEVEKGLTVSEIAARISTSLRKKALGAKINGEKAELMDVINEDSTLEILTFEDQEGKDTLRHTASHILAQAVKRLYPEVKLAIGPSIENGFYYDFDAEFSFTPEILEKIEKEMNKIVKENLQLKKFTKSREDAINFMKERNEDYKVELIEDLPEESIISFYEQGDFVDLCAGPHVPSTKEVKAIKLLSVAGAYWRGNENNKMLQRIYGTAFTKKAELEEYLHMLEEAKKRDHRKLGKELGLFDLKEEGPGFPFFYPKGMILRNTLENYWREMHEKAGYGEIRTPIILNEKLWHQSGHWDHYKENMYFTKIDGEDYAIKPMNCPGSILVYKSDLHSYRELPIRLGELGLVHRHEYSGALHGLMRVRNFTQDDAHIFMTKEQITSEILGVIKMIDNFYSLFGFEYFVELSTRPEDSMGSDEDWEAATNGLIKALNEAGLEYKINEGDGAFYGPKIDFHLRDCLGRTWQCGTIQLDFQMPERFDLSYVGADGEKHRPVMAHRVIFGSIERFIGILTEHYAGAFPTWLAPVQVKIMNITDNQVEYCKEIQKVLNENGIRVELDLRNEKIGYKIREAQLQKIPYMLVLGDKEMNEKTIAVRARKQGDLGAMNLTDFVAMVKKEIEEKTNCL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_STAA3
Sequence: MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVAQSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSEYDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDVFSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIGALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFRTTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA1_EQUGR
Sequence: MVLSAADKTNVKAAWSKVGGNAGEFGAEALERMFLGFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALTLAVGHLDDLPGALSNLSDLHAHKLRVDPVNFKVSPGAGLSTLAVHLPNDFTPAVHASLDKFLSTVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha-1, Alpha-1-globin, Hemoglobin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: TBG1_MAIZE
Sequence: MPREIITIQVGQCGNQIGMEFWKQLCLEHGIGKDGLLEDFATQGGDRKDVFFYQADDQHFIPRSLLIDLEPRVINGIQNSEYRNLYNHENIFVAEHGGGAGNNWASGYHQGEQFVDDIMDMVDREADGSDSLEGFVLCHSIAGGTGSGMGSYLLETLNDRYSKKLVQTYSVFPNQVETSDVVVQPYNSLLTLKRLTLNADCVVVLDNTALNRIAVERLHLSNPTFAQTNSLVSTVMSASTTTLRYPGYMNNDLVGLLASLIPTPRCHFLMTGYTPLTVERQVNMIRKTTVLDVMRRLLQTKNIMVSSYARTKEASQAKYISILNIIQGEVDPTQVHESLQRIRERKLVNFIYWAPASIQVALSRKSPYVQTTHRVSGLMLANHTSIRHLFSKCLGQYEKLRKKQAFLDNYRKFPMFADNDLSEFDESREIIESLVDEYKACESPDYIKWGMEDPGEANVVAALDSKLVV
What is the function of this protein?
Tubulin is the major constituent of microtubules.  The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly.
What are the official names of this protein?
Tubulin gamma-1 chain, Gamma-1-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center.
Protein: Y1998_STAAB
Sequence: MKDLTMLLDELKDMSFFNKGDICLIGCSTSEVIGEKIGTVGSMEVAETIFNALDVVSKETGVTFAFQGCEHINRAITIEKSQFNPLTMEEVSVVPDVHAGGSLATYAFQHMKDPIVVEHITVPCGIDIGQTLIGMHIKHVCVPVRTSVKQVGQAIVTIATSRPKKIGGERAKYQ
What are the official names of this protein?
UPF0340 protein SAB1998c.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: TRSF_DROSI
Sequence: MKMDADSSGTEHRDSRGSRSRSWREREHHGRTSERDSRKKEHKIPYFADEVREQDRIRSLRQRAHQSTRRTRSRSRSQSSDRGSRHRRHRQRSRSRNRSRSRSSERRRRQRSPHRYNPPPKIINYYVQVPPQDFYGMPGMRQSFGYQRLPRPPPFPPAPFRYRQRQPFMGAPRFGYRNAGRPPY
What is the function of this protein?
Member of the regulatory pathway controlling female somatic sexual differentiation, regulated by Sxl.  Activates dsx female-specific splicing by promoting the formation of a splicing enhancer complex which consists of tra, tra2 and sr proteins.
What are the official names of this protein?
Female-specific protein transformer.
What are the subcellular locations of this protein?
Nucleus speckle. Note=Speckled subnuclear compartment.
Protein: FABH_ECOL6
Sequence: MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHIAAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDGAGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVTELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AOX4_AERPE
Sequence: MASGGGFEDLAREAAKYFGVWIVLVASAVAEVYLVLEGIARNPFVFVLAVALFQSSLIALFFQHLRDEPIIIRGITVSGAVLIAILIISAVTSVLTCTPYFPG
What are the official names of this protein?
Heme-copper oxidase subunit 4, Heme-copper oxidase subunit IV.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNAJ_RIPO1
Sequence: MSGDYYETLGVDRNASKEDIKRAYRRLARKYHPDINKEAGAEDRFKEINRAYEVLSEPETRARYDQFGEAGVSGAGAAGFDYGDMGGFADIFETIFSGFGGGVGTGSTRRRTGPTRGDDLRLDLKLDFREAIFGGEKEIRIPHLETCQVCNGSGAKPGTGSRTCSTCNGAGQVRRATRTPFGSFAQVSTCPDCNGAGQVIEQKCDACGGAGRKQETKKLKITIPAGVDNGTRLRVGKEGDAGTRGGTPGDLYVYLFVEPDKEFTREGMNIHSEITISYLQAILGCKLQINTVDGPQELVIPAGTQPNTELMLEDHGVPKLGNSAIRGDHLINVKIAIPTRINNEERELLEKLAHIKGQSHGKGGLEGFLGSLFHK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_FRACC
Sequence: MAKAEKTAAVAEIVEEFRGSTAAVLTEYRGLTVSQLTELRRALGEGTRYSVVKNTLTKIAAEQAGVTGLDDLFVGPTAVAFVSGDPVEAAKGLRDFARANPALVLKGGFVEGKPMTADEIRKLADLESREVLLAKLAGAMKGTLAGAVGLFAAPLSQVARLAEALREQREGQSAGVAEQPAAEAAAE
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: DUT_ECOLU
Sequence: MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: APT_ROSCS
Sequence: MTINLTDLIRNVPDFPVPGIQFKDITPLLQHGAAFKQVIDTLAARYEGRSLDAVVGVESRGFIFSAPLAYRLGIGLVPIRKPGKLPWETFAVEYDLEYGSNKLEMHRDALDPGARVVVIDDVLATGGTVAAACQLVETAGAVVEEVACLIELTLLKGRERLANYSFFSMLQY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.