PharMolix/UniProtQA huggingface dataset:
Protein: GRAR_STAA2
Sequence: MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIILEILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE
What is the function of this protein?
Member of the two-component regulatory system GraR/GraS involved in resistance against cationic antimicrobial peptides (CAMPs).  Upon phosphorylation by GraS, functions as a transcription regulator by direct binding to promoter regions of target genes such as adhesins, exoproteins, transporters, toxins, and proteins involved in cell wall synthesis.  Down-regulates the expression of many genes involved in RNA and amino acid synthesis or glycolysis.
What are the official names of this protein?
Response regulator protein GraR, Glycopeptide resistance-associated protein R.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCN1L_DROME
Sequence: MNKLKSSTHRDKVKKFISLTHTGEQTAIFCLQQNDWKFELASDNYFQNPEYYYRELDRKRIEQLFMRYRDPSDPLKIGSQGVIHFLEDLDLKPDSKLVLIIAWKFHAEVQCEFSRDEFINGMCDLGIDSIDKLKTKLPILEQELNDAGKFKDFYHFTFNYAKDPGQKGIDLEMAIAYWCIVLSGRFKFLDIWCQFLEEKHKRAISRDTWNLLLDFATNIDDRMSNYDSEGAWPVLIDDFVEWCQENDHLKEDSSPASGYQQQSSASSSSQKNISSAYQTSHSTNMNYG
What is the function of this protein?
May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes.  Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity).
What are the official names of this protein?
DCN1-like protein, Defective in cullin neddylation protein 1-like protein.
Protein: BARH1_DROME
Sequence: MKDSMSILTQTPSEPNAAHPQLHHHLSTLQQQHHQHHLHYGLQPPAVAHSIHSTTTMSSGGSTTTASGIGKPNRSRFMINDILAGSAAAAFYKQQQHHQQLHHHNNNNNSGSSGGSSPAHSNNNNNINGDNCEASNVAGVGVLPSALHHPQPHPPTHPHTHPHALMHPHGKLGHFPPTAGGNGLNVAQYAAAMQQHYAAAAAAAAARNNAAAAAAAAAAAAAAGVAAPPVDGGVDGGVGLAPPAGGDLDDSSDYHEENEDCDSGNMDDHSVCSNGGKDDDGNSVKSGSTSDMSGLSKKQRKARTAFTDHQLQTLEKSFERQKYLSVQERQELAHKLDLSDCQVKTWYQNRRTKWKRQTAVGLELLAEAGNFAAFQRLYGGSPYLGAWPYAAAAGAAHGATPHTNIDIYYRQAAAAAAMQKPLPYNLYAGVPSVGVGVGVGVGPAPFSHLSASSSLSSLSSYYQSAAAAASAANPGGPHPVAPPPSVGGGSPPSGLVKPIPAHSASASPPPRPPSTPSPTLNPGSPPGRSVDSCSQSDDEDQIQV
What is the function of this protein?
B-H1 and B-H2 are regulated by members of the wg signaling pathway; wg and dpp.  B-H1 and B-H2 are coexpressed and functionally required in R1 and R6 receptor cells and primary pigment cells for normal eye development.  Coexpression is also required for the fate determination of external sensory organs, formation of notal microchaetae, formation of presutural macrochaetae, antennal development and for distal leg morphogenesis; segmentation and specification of tarsal segments 3-5.
What are the official names of this protein?
Homeobox protein B-H1, Homeobox protein BarH1.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HTPX_SHEON
Sequence: MKRIFLLIVTNLAVLLVASIVMSILGVNTSTMGGLLVFAAIFGFGGAFISLAISKWMAKKTMGCEVITTPRDSTERWLLDTVARQAQQAGIKMPEVAIYQSPEMNAFATGPSKDNSLVAVSTGLLYGMSQDEIEGVLAHEVSHVANGDMVTLTLIQGVVNTFVIFAARVVAGIINNFVSSNDEEGEGLGMFAYMAVVFVLDMLFGILASIIVAYFSRIREYRADEGAARLAGKNKMIAALERLRQGPESSAMPAQMSAFGINGKRSMAELMMSHPPLEKRIAALQSR
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRCA_ECO24
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: CCME_VIBCM
Sequence: MNPRRKKRLGVVLAILFGLSATIGLIIYALNQNMDLFYTPTELVYGKEGKKPEIGQRLRIGGMVVEGSVKRDPNSLKVSFDLHDVGPSITVTYDGILPDLFREGQGIVAQGVLVEPTKIEAFEVLAKHDENYMPPEIAEAMKKTHAPLQYSQEQKQGSDQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: PA24A_XENLA
Sequence: MASIDPYQHIIVEHQYSHRFTVTVIKATNVTKGTFGDMLDTPDPYVELYISSAPDSRKRTKHFNNNINPVWNETFEFILDPNQDNVLEITLMDANYVMDESLGTTTFPILSVKPGEKKQVPFTFNKVTEMILEFSLEVCSSTDLRFSMALCDQEKLFRQKRKNKVINGLRKLLGPEKTQDLNSTSRDVPVIAVLGSGGGFRAMIGFSGVMKALYESGVLDCATYVAGLSGSTWYMSTLYSHPDFPTKGPKEINKELMHNVSYNPLLLLTPQKVKRYVEALWKKKSSGQPVTFTDIFAMLIGETLIKDRMNRKLSHMQEKINDGQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYGTFMPPGLFGSKFFMGTVIKKYEENPLHFFMGVWGSAFSILINRVLGVSNNSKGSTMEEEIENLKPKHILGNDSSDSDDEMQEPKGTENAKAEEEYLRNNQASWVQRMLMAILGDSAIFNTREGRAGKVHNFMLGLNLNTSYPYSPLSGLCTQQSMEEDELDAAVADPDEFEQIYEPLDVKSKKIHIVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWARMNKLPFPKIDPHVFDREGLKECYIFKPKNTSVEKDCPTVIHFVLANLQFRNFKAPGVPRETTEEKESADFDIFDDPETPFSTFNFQYPNVAFKQLHDLMEFNTLNNINVIKQAMVESIEYRRQHPSRCSVSLNDVESRKLHHKDSQSKFQM
What is the function of this protein?
Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid.  Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity).
What are the official names of this protein?
Cytosolic phospholipase A2, cPLA2, Phospholipase A2 group IVA.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle. Note=Translocates to membrane vesicles in a calcium- dependent fashion.
Protein: SFGH2_SHIBS
Sequence: MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEKVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPGKYTSVSAFAPIVNPCSVPWGIKAFSSYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase YeiG, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: PG089_VAR67
Sequence: MGIKNLKSLLLENKSLTILDDNLYKVYNGIFVDTMSIYIAVANCVRNLEELTTVFIKYVNGWVKKGGHVTLFIDRGSIKIKQNVRDKRRKYSKSTKDRKMLELEKCTSKIQNVTGFMEEEIKAEIQLKIDKLTFQIYLSDSDNIKISLNEILTHFNNNENVTLFYCDERDAEFVMCLEAKTYFFTTGEWPLIISTDQDTMLFASVDNHPKMIKNLTQLFKFVPSAEDNYLAKLTALVNGCDFFPGLYGASITPTNLNKIQLFSDFTINNIVTSLAIKNYYRKTNSTVDVRNIVTFINDYANLDDVYSYIPPCQCTVQEFIFSALDEKWNDFKSSYLETVPLPCQLMYALEPRKEIDVSEVKTLSSYIDFENTKSDIDVIKSISSIFGYSNENCNTIVFGIYKDNLLLSINSSFYFNNSLLITNTKSDNIINIGY
What is the function of this protein?
Putative nuclease that seems to be required for double-strand break repair, homologous recombination, and production of full-length viral genomic DNA.
What are the official names of this protein?
Putative nuclease OPG089, Putative nuclease G5.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: SET10_SCHPO
Sequence: MEKLLHEALQNGCKLHKSVEFIQSRDDNACFGSYIAVAQNDIAPDQLLISCPFEYAITYNKAKEELKKLNPNFESCNPHITLCTFLALESLKGIQSKWYGYIEYLPKTFNTPLYFNENDNAFLISTNAYSAAQERLHIWKHEYQEALSLHPSPTERFTFDLYIWSATVFSSRCFSSNLIYKDSESTPILLPLIDSLNHKPKQPILWNSDFQDEKSVQLISQELVAKGNQLFNNYGPKGNEELLMGYGFCLPDNPFDTVTLKVAIHPDLPHKDQKAAILENDCQFQLSNLVFFLPKSPDKEIFQKILQCLAVVTASSLELRKLTAHLLTGDLASYVPSLRGQIKSLEVLLMYIDSRADLLLKSNPQVSPTSERQVWAKIYRDSQINILQDSITYVKNYMEESLQKTYKPLPNLLQYLILNSISIFLLQHPLFAPLSHAIESLYGSTDAEALVATDEQDILMILICVYCLSISEKLPFSISMLVEGYPAVANPEGVEVFEILDEMFFQQFTNVFGESKHFNKENVSWALQLVNDESLDFSGFTFIIAHN
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates ribosomal protein L23 (rpl23a and rpl23b).
What are the official names of this protein?
Ribosomal lysine N-methyltransferase set10, SET domain-containing protein 10.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. RKM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TAZ_HUMAN
Sequence: MPLHVKWPFPAVPPLTWTLASSVVMGLVGTYSCFWTKYMNHLTVHNREVLYELIEKRGPATPLITVSNHQSCMDDPHLWGILKLRHIWNLKLMRWTPAAADICFTKELHSHFFSLGKCVPVCRGDGVYQKGMDFILEKLNHGDWVHIFPEGKVNMSSEFLRFKWGIGRLIAECHLNPIILPLWHVGMNDVLPNSPPYFPRFGQKITVLIGKPFSALPVLERLRAENKSAVEMRKALTDFIQEEFQHLKTQAEQLHNHLQPGR
What is the function of this protein?
Catalytically inactive.
What are the official names of this protein?
Tafazzin, Taz, Protein G4.5.
What is the protein family that this protein belongs to?
Belongs to the taffazin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. SUBCELLULAR LOCATION: [Isoform 1]: Mitochondrion membrane. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Mitochondrion membrane. SUBCELLULAR LOCATION: [Isoform 5]: Mitochondrion membrane. SUBCELLULAR LOCATION: [Isoform 6]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 7]: Mitochondrion membrane. SUBCELLULAR LOCATION: [Isoform 8]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 9]: Cytoplasm.
Protein: RS10_NANEQ
Sequence: MPFLRIKIYSTDLEELNRVVEKIKEIVKQTGVKMRGPIPLPTKILRVPVLRITGHRGTKIWDTYQMRIHRRIIDIATDDRTIKLLMRTPLITKPEKIQIQLKYIKDKNL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: TOXE_COCCA
Sequence: MGTTSPNSEKRQITDINERRKLQNRVAQRKYRTRQKTRMKLAEAVLNDYTYIHPTLGTIQSKKKSPLTMECDRSSASYPDLSSYAEICSETRSETQATRARQLTSQRTCFRESVDNNQADSHAQLSRCLNRQEMFYGISGETEFSEGDTRDRVECIDPNLTRGWLDMDLRSGTPNSSTVVDCGLCTVGANSQPPTRTNVQEAIETLELFEPNDQRKTENLPREPCGSCPSSSHGYSPTSGNPSTLLLTPSESLMNSVIVTSDSPLLAADDKSPGDLVISEANTHGPKEDQFSPLMTAISLGRLDIARILLQSGAPLDIPDDSGKTALHRAVGRRELHMVEALLNLGAEMLATDHEGNSLLHIAVKTNSLSITRLLLERYKSCRELKDAQLGHGCRQHGNQVHSESWIDLRNREGMTAVHLSVIFNRPEILQLLVKYSANVN
What is the function of this protein?
A pathway-specific transcription factor which co-ordinates the expression of genes involved in HC-toxin biosynthesis.  Binds to the tox-box, a 10-bp motif with the consensus 5'-ATCTCNCGNA-3', which is found in the promoter of all genes involved in HC-toxin biosynthesis.  Required for pathogenicity of the fungus on maize.
What are the official names of this protein?
Transcription factor TOXE.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU2C_ALLTE
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFNGSFIFPECILIFGLILLLMIDSTSDQKDRPWFYFISSTSLVMSITALLFRWKEEPIISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKRDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALISITVGIGFKLSPAPFHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNNGYASMITYMLFYISMNLGTFARIVSFGLRTGTDNIRDYAGLYTKDPFLALSSALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIEWSMTVCVIASTIPGISMNPILAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic, NAD(P)H dehydrogenase, subunit 2, NADH-plastoquinone oxidoreductase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NQOR_BRUO2
Sequence: MVKMLVLYYSAYGHMEQMAKAAAEGAREGGAEVTLKRVPELVPEEVAKASHYKIDQEAPIATPGELADYDAIIIGTATRYGMMASQMKNFLDQTGGLWAKGALINKVGSVMVSTATQHGGAELALISTQWQMQHHGMIIVPLSYAYREQMGNDVVRGGAPYGMTTTADGDGSRQPSAQELDDARFQGRRVAEITAKLHG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: STAM1_CAEEL
Sequence: MKKQKSFPMSAYEDLLGKITAPTITVENWEGILAFCDMINNDFEGSKTGIKSLRKRLNNRDPHVVLLAISVLDSCWANCEERFRKEVSSAQFINELKALCTSSQRQVAEKMRLTVQKWVDTECKTEQSLSLIVTLHKNLVADGYSFVVDDPKSKTKAIDAKFANDPNYVGSAQEEEAIAKAIAASLADAEKQEKAKKSTSTMYPSAKASSPAVQTNSNIPEKNVRALYDFEAAESNELSFVAGDIITITDESNPHWWTGRIGTQQGLFPSSFVTNQLDDLKSKETDSSQKAPEVVASINEAILVRCLQVLHECDPTGERQDPEDLAQLEAASYAQGNLIDAHLASIDRQSNSLAQIDVAIRDVLALYDDAIQKGGFQHQSQGMYQQPMQQYNYQQPPNRAYYPPTGPVQQQQPQQYPPQHYPAPGAQPQYACPPNSVPQPQQQQQQWPAPSSQPQQY
What is the function of this protein?
Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base.  Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation.  May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1.
What are the official names of this protein?
Signal transducing adapter molecule 1, STAM-1, Prion-like-(Q/N-rich) domain-bearing protein 19.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Cell projection, cilium. Endosome. Note=Located to early endosomes at the ciliary base but not cilium proper of male-specific sensory neurons.
Protein: FBXW8_HUMAN
Sequence: MDDYSLDEFRRRWQEELAQAQAPKKRRRPEAAERRARRPEVGSGRGEQASGDPALAQRLLEGAGRPPAARATRAEGQDVASRSRSPLAREGAGGGEQLVDQLIRDLNEMNDVPFFDIQLPYELAINIFQYLDRKELGRCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSCWKLIFQECRAKEHMLRTNWKNRKGAVSELEHVPDTVLCDVHSHDGVVIAGYTSGDVRVWDTRTWDYVAPFLESEDEEDEPGMQPNVSFVRINSSLAVAAYEDGFLNIWDLRTGKYPVHRFEHDARIQALALSQDDATVATASAFDVVMLSPNEEGYWQIAAEFEVPKLVQYLEIVPETRRYPVAVAAAGDLMYLLKAEDSARTLLYAHGPPVTCLDVSANQVAFGVQGLGWVYEGSKILVYSLEAGRRLLKLGNVLRDFTCVNLSDSPPNLMVSGNMDGRVRIHDLRSGNIALSLSAHQLRVSAVQMDDWKIVSGGEEGLVSVWDYRMNQKLWEVYSGHPVQHISFSSHSLITANVPYQTVMRNADLDSFTTHRRHRGLIRAYEFAVDQLAFQSPLPVCRSSCDAMATHYYDLALAFPYNHV
What is the function of this protein?
Substrate-recognition component of a Cul7-RING ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  The Cul7-RING(FBXW8) complex mediates ubiquitination and consequent degradation of GORASP1, acting as a component of the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain (PubMed:21572988).  Mediates ubiquitination and degradation of IRS1 in a mTOR-dependent manner: the Cul7-RING(FBXW8) complex recognizes and binds IRS1 previously phosphorylated by S6 kinase (RPS6KB1 or RPS6KB2) (PubMed:18498745).  The Cul7-RING(FBXW8) complex also mediates ubiquitination of MAP4K1/HPK1: recognizes and binds autophosphorylated MAP4K1/HPK1, leading to its degradation, thereby affecting cell proliferation and differentiation (PubMed:24362026).  Associated component of the 3M complex, suggesting that it mediates some of 3M complex functions (PubMed:24793695).
What are the official names of this protein?
F-box/WD repeat-containing protein 8, F-box and WD-40 domain-containing protein 8, F-box only protein 29.
Protein: RPN11_SCHPO
Sequence: MESLQRLLQGARMGTGMMGDQPLVDNSECVYISSLALLKMLRHGRHGTPMEVMGLMLGEFVDDFTVRVVDVFAMPQSGTGVSVEAVDPVFQKNMMDMLKQTGRPEMVVGWYHSHPGFGCWLSSVDINTQQSFEQLTPRAVAVVVDPIQSVKGKVVIDAFRLINPSTLMMGQEPRQTTSNLGHINKPSIQALIHGLGRHYYSLRINYKKTELEEIMLLNLHKQPWAHGLLLENFNSAAEKNHASIDKMKSLSEQYTERVQNEVTLSPEQLRIQYVGKQDPKKHLDAEVQKCIDNNISSMLACMLDSVAF
What is the function of this protein?
Transcription factor pap1 is controlled by the functional interaction between the positive regulator pad1 and negative regulator crm1.  Both these proteins are also essential for cell viability and for the maintenance of chromosome structure.  Pad1 is also responsible for resistance to staurosporine, and other drugs such as cycloheximide and caffeine.
What are the official names of this protein?
26S proteasome regulatory subunit rpn11, Protein pad1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family.
Protein: IDI2_LATSS
Sequence: MVRPKQSIQSHRKDEHVFLAEKFHQDDRQNDFDGLRFIHQSLPELAIADVDISTQFAGTTWQSPFYINGMTGGSQQTKKLNAQLAQVAQIAGLPMATGSQSVAIKDPTLVDTFSVIREFNPAGFILANIGAGNDLSVAQKAVAMTQANALEIHVNTAQEVVMPEGDREFYWLDQIGEIVANLDVPVIVKEVGFGMSAETIAKLQSVGVTNIDVSGKGGTNFVTIENERRRDKAYDYLSDWGQSTVESLFESQAFQTELTILASGGIRNPLDIVKALRLGASAVGISGQILHMLIKTGPTETAEQLLAWQAQIQSIMAILGARNLTALQSAPMILSPNLRHYLNERHLSL
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSZ_PSEF5
Sequence: MPAPVLSGPQYLREGLKLVLSPGLRLFVLLPLAINLVLFVGLIYFAGHQFSLWVDALMPSLPSWLSFLSYVIWPLFVVLVAFMVFFSFTMLANIIAAPFNGFLSEKVETVVRGTDDFPPFSWGELIAMIPRTLAREMRKLGYFLPRAIGLFILSLIPVVNLIAAPLWLLFGIWMMAIQYIDYPADNHKMSWQDMLAWLRQKRWQSLGFGGIVYLALLIPLVNILMMPAAVAGATLFWVRERGVENLPAK
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NFAE_ECOLX
Sequence: MKMRAVAVFTGMLTGVLSVTGLLSAGAYAAGGEGNMSASATETNARVFSLHLGATRVVYNPASSGETLTVINDQDYPMLVQSEVLSEDQKSPAPFWWTPPLFRRDGQQSSRRRSVSTGGEFPSDRESRQWICVKGIPPKEDDRWAEGKDGEKKADKVSLNVQLSVSSCIKLFVRPPAVKGRPDDVAGKVEWQRAGNRLKGVNPTPFYINLSTLTVGGKEVKEREYIAPFSSREYPLPAGHRVRFSGR
What is the function of this protein?
Involved in the biogenesis of the NFA-I adhesin.
What are the official names of this protein?
Chaperone protein NfaE.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CH10_BACCQ
Sequence: MLKPLGDRVVIELVQAEEKTASGIVLPDTAKEKPQEGKVIAVGTGRVLENGERVALEVAAGDLIIFSKYAGTEVKYEGTDYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BUCAT
Sequence: MNKKTKRMKKIKEHINFEKLHHIDETIDLLKKSSTVKFNESIDIAINLGINSKKSDQNIRSSTVLPNGIGRSIRVAVFTQGDNIAIAKDAGAELIGMEDLSEKIKKEGVDFDVVIATPDAMKIVTQLGQILGPRNLMPNTKLGTITTNIAEAIKNAKTGQVRYRNDKNGIIHATIGRINFHKNEIKENLNVFLESIKKAKPPQSKGIYIKKIVLSTTMGVGLMVDQSTLSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RS2_ECOK1
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FDHE_YERPE
Sequence: MSIRIVPKDQLGKQREKGTTAGNIPPLLFANLKSLYTRRTERLQQLALDNPLADYLDFAAKITEAQQKALHDHPLVLDMQAELVQSAASGKPPLDGSVFPRTEHWRKLLSALIAELRHDAPDHILAVLDNLDKASVHELELYADALLNRDFSQVGSEKAPFIWAALSLYWAQMASQIPGKARAEYGEHRQFCPVCGSIPVSSVVHIGTHNGLRYLHCNLCESEWHVVRIKCSNCEQTRDLNYWSLDSELAAVKAESCGDCGTYLKILYQEKDPQVEAVADDLASLILDAKMEGEGFARSSINPFLFPGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_KOCRD
Sequence: MPQLRSATSTTGRNMAGARALWRATGMGSEDFGKPIVAIANSFTQFVPGHVHLKNMGELVASAVQEAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMESGEGVEGVVEHRVDLVDAMSLAVDESVTDAQLAQIEENACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTTLATHVNRKRLFLEAGRRAVESAKKYYEQDDESVLPRSIATKAAFENAMALDIAMGGSTNTVLHILAAAQEAEVDFNLSDIDALSRQVPCLAKVAPNSTTFHIEHVHRAGGIPAILGELRRGGLLNEDVHTVHSQTMGEWLDEWDIRSGKASDAAKEFFLAAPGGVRTTQAFSQANEYEDHDVDAAGGCIRSVEHAYTKEGGLCVLFGNIAEDGAVIKTAGIDPELFHFTGRAFVVESQDEAVHEILSKNVKEGDIVVIAYEGPKGGPGMQEMLYPTSYLKGLGLGKKCALITDGRFSGGTSGLSIGHISPEAAAGGAVGLVQHGDEIEIDVENRVLRVNVDDAELARRRQEKGDAPWKPTKPRERRVSKALKAYASMVTSADKGAVRVVED
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: TOP3C_OXYTA
Sequence: GMKDYFKKLLQKVIKKIKSFRKKQD
What is the function of this protein?
May have cytolytic and antimicrobial activity.
What are the official names of this protein?
Oxyopinin-3c, Oxt-3c.
What are the subcellular locations of this protein?
Secreted.
Protein: CINAL_FUSNN
Sequence: MKAGIFLVGTELLNGATIDTNSIYIAEELNKYGIEIEFKMTVRDVMSEITKALTYAKKNVDLVILTGGLGPTDDDITKEAMAKFLKKKLVVDEKEKKELLKKYKAYKNPNKTNFKEVEKPEGAVSFKNDVGMAPAVYIDGMVAFPGFPNELKNMFPKFLKYYVKENNLKSQIYIKDIITYGIGESVLETTVKDLFTEGDIFYEFLVKDYGTLIRLQTKIENKKNVAKIVKKLYNRISEFIIGEDDDRIENTIYECLNLGEKPLTISTAESCTGGMVASKLIEVPGISENFIESIVSYSNEAKIKRLKVKKETLEKYGAVSEEVAREMLAGLKTDIGISTTGIAGPGGGTKDKPVGLVYIGIKVKNEVKVFKRELKGDRNKIRQRAMMHALYNLLKILSKKVR
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.