PharMolix/UniProtQA huggingface dataset:
Protein: GPDA_BURCM
Sequence: MKVAVLGAGAWGTALAGHLAARHDTLLWARDAALIAGLQARHENSRYLDGIALPDALRYDADLGAALAHGAADDALCVIAAPVAGLRTLFGAMRDAGCVPAHVVWVCKGFEADTHLLPHQVIAAELPGQHSNGVLSGPSFAREVGLALPVALTVASTSAECRERTLAAFHHGAMRIYTGDDVVGVEVGGAVKNVLAIATGIADGLGLGLNARAALVTRGLAEMSRLGVALGGRAETFTGLTGLGDLILTATGDLSRNRTVGLQLAAGRSLNDILGALGHVAEGVRCAQAVLALARAQSIEMPITEAVCGVLFDGVAPRDAVSGLLRRDARAE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4HYPE_CHRVO
Sequence: MKQVEIIDSHTGGEPTRLVLSGFPALAGATMADKRDALRERHDQWRRACLLEPRGSDVLVGALYCEPVSPDAACGVIFFNNTGYIGMCGHGTIGLIASLHCLGRIAPGAHKIDTPVGPVDAVLHEDGSVTLRNVPAYRYRRQAAVEVPGHGTVIGDIAWGGNWFFLVAEHGLSVRLDNVAALSAFSCATMQALEEQGITGADGARIDHVELFADDEQADSRNFVMCPGKAYDRSPCGTGTSAKLACLAADGKLAEGEQWVQAGITGSRFVGHYQREGDFIRPYITGRAHITARAMLLIDEQDPFAWGI
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate.  Can also catalyze the epimerization of trans-3-hydroxy-L-proline (t3LHyp) to cis-3-hydroxy-D-proline (c3DHyp), albeit with 19-fold lower efficiency.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: Y3945_RHILO
Sequence: MAGHSQFKNIMHRKGRQDAVRSKMFSKLAREITVAAKSGTPDPSMNPRLRLAIQNAKAVSMPKDNIQRAINKASMGDAENYEAVRYEGYGPGGVAVIVEALTDNRNRSASNVRAAFTKAGGAMGETGSVSFMWDRVGEIYYPASAGSADKVMEAAIEAGADDVESDEEGHTIYCAFENLGEVSKALEAALGEAESVKLIWRPQNNVPVDEERAQSLMKLVATLEDDDDVQSVYANFEVDDETLAKLSAA
What are the official names of this protein?
Probable transcriptional regulatory protein mll3945.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y16K_BPT4
Sequence: MKSFKDVKVGEIFCLDNGDQLIRISPLKSTSEKMTVNATLANNSNERFCIENDTETYTVEEFWELSVDCDE
What are the official names of this protein?
Uncharacterized 8.1 kDa protein in ndd-denB intergenic region.
Protein: RK36_THEPA
Sequence: MKTKTSIKQICNLCKIVRRNKRLVNTCKLHKNHKHKQK
What are the official names of this protein?
50S ribosomal protein L36, apicoplast.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, apicoplast.
Protein: DTD_DINSH
Sequence: MRALIQRVTEASVRVEGAVIGRTGPGLLVLVCGMPGDTDRSVAALAGKIAKLRIFRDAEGRMNRSLLDVGGGALVVSQFTLAADTSRGNRPGFSAAAPPKEGERLYEAFAAALAETGVAVETGRFGANMAVALVNDGPVTIWMEG
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT5G1_RAT
Sequence: MQTTKALLISPVLIRSCTRGLIRPVSASLLSRPEAPSKKPSCCSSPLQVARREFQTSVISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
What are the official names of this protein?
ATP synthase F(0) complex subunit C1, mitochondrial, ATP synthase lipid-binding protein, ATP synthase membrane subunit c locus 1, ATP synthase proteolipid P1, ATPase protein 9, ATPase subunit c.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: NRDI_WIGBR
Sequence: MSVLVYFSSSSENTHRFVKKLCIPAKRIPLIDKKEFQIKSPYILVIPSYNNGILDTAVPHQVTNFLNTLHNKFFLKGVIGSGNKNFGVNFCIAGNIISKKYKVPLLYKFELLGTNKDVINVKNGINKFWKKLNLEKKNQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: VATF_THEAC
Sequence: MESCITVIGERDVVLGFRLLGIQHTIIAEGKDLLKKFLEVFQNPQCNIIIVSENVKNMMDKRTLRSVEISSKPLVVFIPLPGVREEETIEEMAKRILGIDIGNV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: ZEAZW_MAIZE
Sequence: MATKILSLLALLALFASATNASIIPQCSLAPSSIIPQFLPPVTSMAFEHPAVQAYRLQQAIAASVLQQPIAQLQQQSLAHLTIQTIATQQQQQQFLPALSHLAMVNPVAYLQQQLLASNPLALANVVANQQQQQLQQFLPALSQLAMVNPAAYLQQQQLLSSSPLAVANAPTYLQQELLQQIVPALTQLAVANPVAYLQQLLPFNQLTMSNSVAYLQQRQQLLNPLAVANPLVAAFLQQQQLLPYNRFSLMNPVLSRQQPIVGGAIF
What is the function of this protein?
Zeins are major seed storage proteins.
What are the official names of this protein?
22 kDa alpha-zein 14, 22 kDa zein PZ22.3, Zein-alpha PZ22.3.
What is the protein family that this protein belongs to?
Belongs to the zein family.
Protein: YFIM_ECOLI
Sequence: MRILFVCSLLLLSGCSHMANDSWSGQDKAQHFIASAMLSAAGNEYSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDLAWDVAGASTGYTVWQLTRH
What are the official names of this protein?
Uncharacterized protein YfiM.
Protein: TIM13_DANRE
Sequence: MEGFGSDFSSGSSSGKMDTGTIMEQVKVQIAVANAQELLQRMTDKCFKKCIGKPGSTLDNSEQKCIAMCMDRYMDAWNTVSRAYNSRLQRERAHI
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIMM8-TIMM13 complex mediates the import of some proteins while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RL19_SALPC
Sequence: MSNIIKQLEQEQMKQNVPSFRPGDTVEVKVWVVEGTKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSIAVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: REGQ_BP82
Sequence: MNTQYLQYVREQLIVATADLSGATKGQLEAWLEHAQFDTGTYKRKKPRILDEVTGRMITLDNPPISGKQSYAKGSSIALVSQVEFSTSSWRRAVLSLEEHQKAWLLWSYSESVRWEHQVTITQWAWSEFKTLLGTRKIAGKTLERLKKLIWLAAQDVKNELAGRKTYEYQELASLVGVTSKNWSETFTERWVAMKHIFLQLDSEALLLLTRTRSKQKATFSQQNIAKLD
What is the function of this protein?
Positively regulates expression of the phage late gene operons.  Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes.
What are the official names of this protein?
Antitermination protein Q.
What is the protein family that this protein belongs to?
Belongs to the phage antitermination Q type 1 family.
Protein: MAP1_BORBU
Sequence: MTKLRLKSKDEIKKIKASASLLALTLLEVERNIVPGISTKELDLIAYDFIIKNRAKPAFKGYRGFKGTICASVNEEVIHGIPGKRKLADGDIVSIDCGVILDGFYSDMAKTFKVGNVDSSIDKLLEVTNASLYKGIAEMKVGNRILNISKAIEDYIKPFGFGIVREYTGHGVGFELHEEPSVPNYYAPFFKNIRIQEGMVLAIEPMVNLRGHKVSIKSDGWTVFASDLSYSAHFEHTVAVVDGLPLILSEV
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: SLMA_SHEAM
Sequence: MAAKEKISRREHILQCLAQMLETNPGQRITTAKLAAEVGVSEAALYRHFPSKARMFEGLIEFIEDSLLSRINLIMDDEKDTMRRCQLVLQLLLLFAERNPGISRVLNGDALLGENERLRSRVSALFGKIETQLKQILREKTLREGKGFELDEAMLANLLLAVAEGRIAQYIRSEFKQKPTEHFDEQWGFIQKQLLQS
What is the function of this protein?
Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid.  Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers.  SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
What are the official names of this protein?
Nucleoid occlusion factor SlmA.
What is the protein family that this protein belongs to?
Belongs to the nucleoid occlusion factor SlmA family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FABH_HERAR
Sequence: MTLYSKIIGTGSYLPPNRVTNQDLIERLALDGIETSDEWIVSRSGISARHYADADMQSSDLAVEAAKRALDMAKLAANDIDLIILATSTPDFFGGFPSTACVVQRKLGVTNGCAAVDVQAVCSGFVYALATADKFIKSGSHKNVLVIGAEVFSRIIDFKDRTTCVLFGDGSGAVVMTASEEPGVLATKLHADGSYGDILCGPGRISNGVLEGSAFMYMDGQAVFKLAIGLLDKVANEVLQLAKMDASEVDWIVPHQANIRIMQGTAKKLGLSMDKMIVTVDQHGNTSAASIPMALDVGVRDGRIKPGQNVMMEGVGGGFTWGAVLARM
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1298_PSEP1
Sequence: MKRICSIYKSPRKNEMYLYVLKADGLERVPEGLLPFFGTPVHAFDLVLSPERKLAREDITKVLENLESQGYHLQMPPLEDEYIEHLPEELLRRNDPV
What are the official names of this protein?
YcgL domain-containing protein Pput_1298.
Protein: YBU1_SCHPO
Sequence: MDPHWKRHDSSNIPTQPSPSASPKSNKPSSAQRFGNLPWVAPDVIQSQIEYLQALQMQQSLSESENYLQPNFFPFQSGPFSKSRRENTLLPRLNPLAPIGARQPNPSIPQQFSKPINESGTGTMGPAVGELTSPVMKNRAESIFSPVTESFEAFTQGMQTTPQRAGAGVSTATSHTRRRSSAGTDPFSPVSPSNPNFLTPLKPIDGNQEWQQSPLESPLSMHSLQESLHSVEPESPIFQQAPQIPLSNASQQSYINHSSDGASLPQSSFLNFNSSGKRVSVSAAAQQHKNLFLPYLPQASLPKFIGTGKLLVGTLHINRKNRSDAYVITDVLDEPIFICGSKDRNRTLEGDLVAVELLDVNEIMQTKREKEEKKIRRNLSLSGSSKYSVNSKAKMMSISTPMALGMNRGVLSFERSIEKRKNDYEVTGQSLSFVDDVSLTPDSAPKYAGHVVAVLNRPSGETCSGTLALYRPNSLALKNQSSHRRNSSTSSGETGKGPKIVWFKPSDKRIPLIAISSDQVPPTFFTNNDDFKDKVFLAGIKRWPTTSLHPFGTLYESIGTIGDPKVEYKAILHDFSCHTYDFPESLSHCVKRLPTPIPAEELQKRYNLRDKLTFMIGTRDYALHIDTGSIDGVITLGIHVADVAYYVKQDMPLDDEAANRVSEVQLLQGSVPFLPKKVSEEISLIEGHDCLTISIVVQLDLKSGAVLQCSLGPSVIHPSSFISLESAQANLQTNEALQLVDASAHVLTKLRLKTDKKLDLQSLYCFEFCDGQIPNIQNINMSIFEAFPIACSLQQIEHWVNEKVASHLMSVFPSKVILRKNQRPSDFASLVAVSELTGVNLSASSTPSEIMTEIATTKDKRTKMLLQLTLRRMCNESEYTIGTSNAKDVSHFVFSCPYYTHFCHPTRRYIDICVQRQLREAFDGRPDFSKDYRSLLSITQSCNTLSNFYRNAQEKSLHAYLCQLLHSINLRSGLVKHKAFVLAVDQEYIDIVIYEFGLERRISLDLLPLSNCDFNEQKHELYLSWRTNASFFYASSSLEIDTPCFNDFKKKFLDSNGMCKQICDMMDAQVRDLANAAESQESFYSKARGNDSTSKTAKSSSGNQDISGDGKLHSLRMKEPEVVQTIRPGQEVSVLIFADTSATYSLSLITLQSPLSS
What are the official names of this protein?
Uncharacterized ribonuclease C609.01.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODH_RHITR
Sequence: MIHSLPSPEPFVILAMPRTGTHYLEALLNDHPNILSNGELLNSYDENWPDKDRLRHSDRELLELAYMRYPPAKKKVTHVGCKINEPQFYERPGFFDELARWQGLKVILLTRNTLESLRSLVQARQTGQWLKFSPDRNEPPSVSLSVNECEAYFKAADDFHARVKDAFDPSKLLMIEYQDLLLKPSACLAAVLAFLGAPAHRFSNRATIQRQETRSLARSLRNFVELRRHFAGGPYAKFFELDDASAPQG
What is the function of this protein?
Required for the formation of sulfated nod factor.  Proposed to transfer activated sulfate (PAPS) to a N-acetylglucosamine of the nod factor.
What are the official names of this protein?
Nodulation protein H.
Protein: MUTS_METPP
Sequence: MSADPARAESGHTPMMQQYLRIKAEHPDTLVLYRMGDFYELFFDDARKAHRLLDITLTSRGQSAGEPVVMAGVPVHALENYLGKLVKLGESVAIAEQVGDVATAKGPVERKVVRVVTPGTVTDTELLSERVDTLLLAVTRQRASYGLAWLGLSSGTLGLSECGERELAGWLARLGPAEVLVDDRDDAALTAALSTTRTALTRRPAWQFDTALGRRKLCEQLRVASLAGFNAEDVSAAHAAAAALLSYAEHTQGRALAHVGSLAVERASDLLELPPATHRNLELTQTLRGEDAPTLLSLLDVCRTGMGSRALRHWLTHPARVRTAARARHEAIGALMERGGEVLREALRGVSDVERITARIALRQVRPRELTGLRATLLALPALRDGVPRDSALLADLAQQLSPPPEIADLLQRAIADEPAVLLRDGGVIATGHDAALDELRGIAQNCEAFLLDLEARERNRTGIANLRVQFNRVHGFYIEVTQGQVDKVPADYQRRQTLKNAERYITPELKAFEDKALSAQERALAREKLLYDGVLDALQPQLAALGAVARALASLDALAALAERAAVLNWCCPEFVSQPCIEIEQGRHPVVEARLAETGGGSFIPNDCRLDANRRMLVITGPNMGGKSTFMRQVALVVLLAAMGSYVPAAACRLGPVDAIHTRIGAADDLANAQSTFMLEMTEAAAIVHGATEHSLVLMDEIGRGTSTFDGLALAGAIASQLHDRNRAFTLFATHYFELTAFPEKHPRALNVHVSAAESHTGHGDDIVFLHEIQPGPASRSYGVQVARLAGMPAPLLRQARATLEALEAQQAASASQIDLFAAPPPSPPREATELERALAGVEPDTLTPREALDALYRLKSLHERSKEN
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL1_HALSA
Sequence: MADNDIEEAVARALEDAPQRNFRETVDLAVNLRDLDLNDPSQRVDEGVVLPSGTGQETQIVVFADGETAVRADDVADDVLDEDDLSDLADDTDAAKDLADETDFFVAEAPMMQDIAGALGQVLGPRGKMPTPLQPDDDVVDTVNRMKNTVQIRSRDRRTFHTRVGAEDMSAEDIASNIDVIMRRLHANLEKGPLNVDSVYVKTTMGPAVEVA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1, HL8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: BLT2_ECOLX
Sequence: MVTKRVQRMMSAAAACIPLLLGSPTLYAQTSAVQQKLAALEKSSGGRLGVALIDTADNTQVLYRGDERFPMCSTSKVMAAAAVLKQSETQKQLLNQPVEIKPADLVNYNPIAEKHVNGTMTLAELSAAALQYSDNTAMNKLIAQLGGPGGVTAFARAIGDETFRLDRTEPTLNTAIPGDPRDTTTARAGADVASLRWVMRWAKPSGAVGDVAQRQYDRAAGIRAGLPTSWTVGDKTGSGDYGTTNDIAVIWPQGRAPLVLVTYFTQPQQNAESRRDVLASAARIIAEGL
What is the function of this protein?
Hydrolyzes beta-lactam antibiotics such as penicillin G, carbenicillin, cephaloridine, cefoxitin, cefotaxime, ceftazidime, and aztreonam.  Has especially increased relative hydrolysis rates for cephalothin, cephaloridine, cefotaxime and ceftizoxime.
What are the official names of this protein?
Beta-lactamase Toho-2.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: BPPF_AGKPI
Sequence: QLWPRPHIPP
What is the function of this protein?
This peptide potentiates the effect of bradykinin on the isolated guinea-pig ileum, does not potentiate the effects of bradykinin upon blood pressure and inhibits the angiotensin-converting enzyme (ACE) from rat plasma.
What are the official names of this protein?
Bradykinin-potentiating peptide F, AppF, BPP-F.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: M2DH_PYRTR
Sequence: MPPQVARNLLRAARARAVFQSTRPAHRRPAAISCRFQSTEAVRQTPSDVYQAPPRGFVPRKEEKFVPTQSRKAAPAATLKLNSKNLSSLQNVSVPTYKRHGVKQGIVHVGVGGFHRAHLAAYVDTLLEQFNVQDWSICGVDLQPFAAPMRDALKPQDNLYTMIERAADGTSARVIGSITDYLFAPDSAEAVIAKMAHPDTHIVSMTVTESGYYMNENTHELQIDHPDVAADLAGEQPARTVFGYLYAAMARRHAAGLRPFTVLSCDNMQKNGDISRNMLVSFARHAGNNEVADWIASNGAFPNSMVDRITPRTNDEDKVSLAKNFGVEDAWPVVTEPFHQWVLEDKFVDGRPPFEKAGVQIVPDVHQVEEYEMIKLRLLNGSHSAMGYAGQLAGFTYIHEVISHPVYRQFVINMMQQEVKPLLPQIPGVSVDDYCNTLLGRFSNPTLKDELPRICLGGSGKIPQFIMPSIAEQIIAGGPLRRLTLVAAAWFRYNKGIDDAGNAFKVDDPMVEELQAKAAEGPIAQLQIKNLFGDDLRQDKRFVQELKTALEGLEREGALAMIEKYA
What is the function of this protein?
Catalyzes the NAD(H)-dependent interconversion of D-fructose and D-mannitol in the mannitol metabolic pathway.
What are the official names of this protein?
Mannitol 2-dehydrogenase, M2DH, MDH.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: DCUP_NITOC
Sequence: MAELKNDRFLRALLRQPVDRTPIWIMRQAGRYLPEYREVRAKAGDFLTLCTTPELACEVTLQPLRRFDLDAAIIFSDILTIPHAMGLGLYFSKGEGPRFERPVRTKNQVSALGVPDPESDLSYVMEALRLTRRELDGRVPLIGFSGSPWTLACYMVEGGSSKDFALIKGLMFEHPQVMHHLLEILAQAVTVYLNAQIAAGAQAVMLFDTWGGALSHRDYRDFSLSYMARIVEGVVRENEGRQVPVILFTKGGGLWLETMAGTGCDALGVDWTVDLAKARMQVGKQVALQGNMDPCVLYASSERVRQEASEIIKAYGAGSGHVFNLGHGIHPTVMPEKVAALVDAVHELSVPYHTYEE
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGN_SCHPO
Sequence: MSDFYVRYYSGHHGRFGHEFLEFDYHSDGLARYANNSNYRNDSLIRKEMFVSELVLKEVQRIVDDSEIIKESDESWPPENKDGKQELEIRMNGKHIMFETCKLGSLADVQNSDDPEGLKVFYYLIQDLKALCFSLISLNFKLRPVKN
What are the official names of this protein?
Protein mago nashi homolog.
What is the protein family that this protein belongs to?
Belongs to the mago nashi family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DHB4_MOUSE
Sequence: MASPLRFDGRVVLVTGAGGGLGRAYALAFAERGALVIVNDLGGDFKGIGKGSSAADKVVAEIRRKGGKAVANYDSVEAGEKLVKTALDTFGRIDVVVNNAGILRDRSFSRISDEDWDIIHRVHLRGSFQVTRAAWDHMKKQNYGRILMTSSASGIYGNFGQANYSAAKLGILGLCNTLAIEGRKNNIHCNTIAPNAGSRMTETVLPEDLVEALKPEYVAPLVLWLCHESCEENGGLFEVGAGWIGKLRWERTLGAIVRKRNQPMTPEAVRDNWEKICDFSNASKPQTIQESTGGIVEVLHKVDSEGISPNRTSHAAPAATSGFVGAVGHKLPSFSSSYTELQSIMYALGVGASVKNPKDLKFVYEGSADFSCLPTFGVIVAQKSMMNGGLAEVPGLSFNFAKALHGEQYLELYKPLPRSGELKCEAVIADILDKGSGVVIVMDVYSYSGKELICYNQFSVFVVGSGGFGGKRTSEKLKAAVAVPNRPPDAVLRDATSLNQAALYRLSGDWNPLHIDPDFASVAGFEKPILHGLCTFGFSARHVLQQFADNDVSRFKAIKVRFAKPVYPGQTLQTEMWKEGNRIHFQTKVHETGDVVISNAYVDLVPASGVSTQTPSEGGELQSALVFGEIGRRLKSVGREVVKKANAVFEWHITKGGTVAAKWTIDLKSGSGEVYQGPAKGSADVTIIISDEDFMEVVFGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
What is the function of this protein?
Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway (PubMed:17442273).  Catalyzes two of the four reactions in fatty acid degradation: hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx.  Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates (By similarity) (PubMed:17442273).
What are the official names of this protein?
Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MFP-2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: MODC_VIBVU
Sequence: MKGLQVAFKQTLGHVVFDIELQLPSKGVSAIFGRSGAGKTSIINVISGLTQPEQGRIALNSDVLFDSVLGINVPVHQRNIGYVFQDSRLFPHYHVEGNLKYGVKQYDAEMFDKVVTLLALQPLLKRYPASLSGGEKQRVAIGRALLSSPKILLMDEPLASLDMPRKKEVLPFLEKLSESFEIPIVYVTHSLQEILRLADHLTVLDRGQIVASGLLSEVWSSQAMRPWQSFSEQSTLFNANIAEQHPQYALTRVMLSSTASLWVQKIDAPLGSDIRLQVRANDVSITLVQPQKTSIRNIIEAKVERVEKRHPAEDKESIAVKLALTQDCFLWATITPWALADLNLKQGDRVFAQIKGVSVTQRDIALTH
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ITR4_CUCMA
Sequence: HEERVCPRILMKCKKDSDCLAECVCLEHGYCG
What is the function of this protein?
Inhibits trypsin.
What are the official names of this protein?
Trypsin inhibitor 4, CMTI-IV, Trypsin inhibitor IV.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEN10_HUMAN
Sequence: MAAAEVADTQLMLGVGLIEKDTNGEVLWVWCYPSTTATLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYITTIEVPDSSILKKVTHFSIVLTAKDFNPEKYAAFTRILCRMYLKHGSPVKMMESYIAVLTKGICQSEENGSFLSKDFDARKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYVHLNADELEALQMCTGYVAGFVDLEVSNRPDLYDVFVNLAESEITIAPLAKEAMAMGKLHKEMGQLIVQSAEDPEKSESHVIQDIALKTREIFTNLAPFSEVSADGEKRVLNLEALKQKRFPPATENFLYHLAAAEQMLKI
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B.  Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form.
What are the official names of this protein?
DENN domain-containing protein 10, Protein FAM45A.
What is the protein family that this protein belongs to?
Belongs to the DENND10 family.
What are the subcellular locations of this protein?
Late endosome.