PharMolix/UniProtQA huggingface dataset:
Protein: DEP1_YEAST
Sequence: MSQQTPQESEQTTAKEQDLDQESVLSNIDFNTDLNHNLNLSEYCISSDAGTEKMDSDEEKSLANLPELKYAPKLSSLVKQETLTESLKRPHEDEKEAIDEAKKMKVPGENEDESKEEEKSQELEEAIDSKEKSTDARDEQGDEGDNEEENNEEDNENENEHTAPPALVMPSPIEMEEQRMTALKEITDIEYKFAQLRQKLYDNQLVRLQTELQMCLEGSHPELQVYYSKIAAIRDYKLHRAYQRQKYELSCINTETIATRTFIHQDFHKKVTDLRARLLNRTTQTWYDINKERRDMDIVIPDVNYHVPIKLDNKTLSCITGYASAAQLCYPGEPVAEDLACESIEYRYRANPVDKLEVIVDRMRLNNEISDLEGLRKYFHSFPGAPELNPLRDSEINDDFHQWAQ
What is the function of this protein?
Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
What are the official names of this protein?
Transcriptional regulatory protein DEP1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CMAH_ASTRU
Sequence: MEQEREIVFSLSPEETSELKNGVNLISRSEKEKFVIYKDPTAENTVEEPATSHMYKACLNKCKHQGGTFIKDIEDGDNCILRCTKHGWKLDAKTMRYVNPPDSFSQQQLVPEYNEDGSLDIVELKPPQPWETDKRDPMPLEVGEVQITYFTHACIEIKLGDLIMFTDPWLIGPAFARGWWLMHEPPADWLDRLAKADLIYISHLHSDHLNYPTLELLSQRNPDIPIYVGDTSMPVFVRLEQSGVKLNNIHIKKFGKWIEINKDTRFMIMMDGVHPDMDTCALIDYKGHLILDTVDCTNPNGGRLPIGVDMMLSDFAGGASGFPMTFSGGKYTEEWKAEFVKRERRKLLYYKMQQVRDVAPTVYCPFAGYFVEAHPSDHYIRSTNTKNDPDALNALINKYSPNIKTWSPSPGAVLDLKKAIQGDRDFITDPPRGTQKFKDSWDFEKYVNAINKNIEEEIFSYPEWIQFYYKWTGFKNYNLVIRMVERDDDFCPVVGGYDFMVDFVGEEPTFPTERPAREHSYLEMENRIGVHRETVRQGLFWDDLYIGFNNRISREPDTFHYLFWNHMQILLPRTDPDWEGFLRDMKTEGAPQKAIWNPSQATPAVEAKDPSSDSKDSATKPGTHWNYERLLRPLGIVVALVGVGVAIWKSESK
What is the function of this protein?
Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions.  Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.
What are the official names of this protein?
Cytidine monophosphate-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminic acid hydroxylase, CMP-N-acetylneuraminate monooxygenase, CMP-Neu5Ac hydroxylase, CMP-NeuAc hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the CMP-Neu5Ac hydroxylase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL5_EHRRG
Sequence: MLKDLYKTQIVPSLQNKLGYSNVMQVPKIVKVCLNMGLGIRGSDSKVMNSCVRDLALIAGQKPVATSVKRSIAGFKIRKGFPIGCKVTLRNNKMYEFLERLIYVVLPREQDFKGLSINQFDGCGNISIGIKEHISFLEVDYDKIDKILGLDINIVTNAVNNKDAKLLLMEFGLPFIN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: CCYL1_XENTR
Sequence: MGNTVTCCVSPDASPKAGRDRAVTERGEPYQAQVELQETDPGPHLQHISDREFPVDFHDEPNPSDHPQASTIFLSKSQTDVREKRKSNHINHVSPGQLTKKYSSCSTIFLDDSTVSQPNLRSTIKCVTLAIYYHIKNRDSDRSLEIFDEKLHPLTREEVADDYCKHDPDHKHIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPSNWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNEMERHFLELLQFNINVPASVYAKYYFDLRSLADDNNLSFLLEPLSKERAQKLEAISRLCEDKYKDLSKAAMRRSISADNLVGIRRSNAIIS
What are the official names of this protein?
Cyclin-Y-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin Y subfamily.
Protein: AT5F1_DROME
Sequence: MFSRAALLTAQRPLTVAATRSAAAAAAPGGAIERRQRPEHPGKVRLGFLPEEWFQFFYNKTGVTGPYTFGVGLITYLCSKEIYVMEHEYYSGLSLGIMAIIAVKKLGPVIAKWADGEIDKIESEWKEGREAELKVLSDAIEAEKKEQWRADGALLLMEAKKENIALQLEAAFRERAMNVYSEVKRRLDYQVECRHVERRLSQKHMVNWITTNVLASISPQQEKETLNKCIADLSALALRVKSA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase subunit b, mitochondrial, ATPase subunit b, FO-ATP synthase subunit b.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: CCS1_MICAN
Sequence: MTISETSSNLKNTPPQWGRKFIQTIADLRLAIILLLLIAIFSISGTVIEQGQSLSFYQANYPEKPALFGFLTWKVLLLLGLNHVYSTWWYLSLLILFGSSLTACTFRRQLPALKAARNWQFYQQSRQFQKLALSAELETGSLESLTPLLEKKGYKVFLENNSLYARKGLIGKIGPIIVHAAMLIILAGAIWGALTGFFAQEMVASGDSFQVKNIIEAGPLSKNSLPKDWGIKVNRFWIDYSPKGDIEQFYSDLSVIDNQGQEIDRKTIQVNQPLHHKGVTFYQTSWGIAGVKVQVNNSPILQLPMASLDTKGNGQIWGTWIPTKTDLSEGVSLLTRDLQGTVIVYDAQGDLTSAVREGMTIPINGVNLKIVELVGSTGLQIKADPGVPIVYLGFALLMMGVVMSYFSHSQIWALQSGDRFYIGGKTNRAQVSFEREIIDTIERLKLK
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: CSOSC_HYDCU
Sequence: MSTEYGIALGMIETRGLVPAIEAADAMTKAAEVRLVSREFVGGGYVTVLVRGETGAVNAAVRAGADACERVGDGLVAAHIIARPHKEVEPVLALGNSSPDRS
What is the function of this protein?
One of shell proteins of the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, ccbL-ccbS) is sequestered.  Assembles into hexamers which make sheets that form the facets of the polyhedral carboxysome.  The shell probably limits the diffusion of CO(2) into and out of the carboxysome.
What are the official names of this protein?
Carboxysome shell protein CsoS1C.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family. CsoS1 subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.
Protein: LIPA_AZOSB
Sequence: MDNPARKQRGAEKTARIPIKIVPAERLKKPDWIRIRLGAGAEAERFNEIKQTLREHKLHTVCEEASCPNIHECFGKGTATFMIMGDICTRRCPFCDVGHGRPEPLNPNEPTDLARTIAAMRLNYVVITSVDRDDLRDGGAQHFVDCIRETRAASPSTTIEVLVPDFRGRMEIALEIFNQAPPDVMNHNMETVPRLYKQARPGADYAYSLRLLKEFKAGHPDVLTKSGLMVGLGETDDEILDVMRDLRAHDVDMLTIGQYLQPSGGHLPVLRYVHPDTFKMFETEALRMGFRNAACGPMVRSSYWADQQAHGAGVV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_ALBFT
Sequence: MSKDDVIQMQGEVVENLPNATFRVKLENGHVVLGHISGKMRMHYIRILPGDKVTVELTPYDLSRARIVFRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_SINFN
Sequence: MNLTPREKDKLLISMAAMVARRRLERGVKLNHPEAIALITDFVVEGARDGRSVAELMEAGAHVLTRDQVMEGIAEMIHDIQIEATFPDGTKLVTVHEPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINA_CALBD
Sequence: MVAEIICVGTELLLGQILNTNSQYLAQKLAELGIDLYFQTTVGDNMERLKMAIDIATKRSDVLIFTGGLGPTSDDITKEAVADYFGLTLVLDEDILRRIESFFERRQVKMPQINKKQAYVPEGAKVLHNKNGTAPGLIIEKDGKIAILLPGPPFEMQPMFEEEVLPYLEKFSKQKIYSRVLKFIGIGESSIEEALKDLILSQTDPTMALYAKPFEVELRITTKKESEELAKSLLQSMEYRIRERLGEYIYGVDRQLLEEVVIGLLTEKKLKVSVAESCTGGLICNKLTNVPGASEVFDRGFIVYSNEAKMKLLGVPEQVLKEHGAVSSQTARFMAQGALSNSLSDIALSVTGIAGPGGGSETKPVGLVYIGIATKDNVESFEFRFSGDRLRIKEMTSKAALNILRKKIIDY
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: GST_SERMA
Sequence: MKLFYKAGACSLSPHIVLRELGLDFTAXKVD
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase GST-7.3.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_YERPS
Sequence: MLEKQSVNQKEQYNFNKLQKRLRRNVGQAIADFNMIEEGDRVMVCLSGGKDSYTMLDILQSLQKSAPINFSLIAVNLDQKQPGFPEDILPAYLDKQGVEYKIVEENTYGIVKEIIPDGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKLKGMPPKLMSDDGKHIVIRPLAYCREKDIERFAVAREYPIIPCNLCGSQPNLQRQVIKDMLRDWDKQYPGRIETMFSAMQNVVPSHLNDHKLFDFKSITHDSDIIDGGDLAFDREALPLNPVGWQPEDDEDTEKRPSVRLDVLEIK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDP1L_MOUSE
Sequence: MSEDMEFENWGSTQSSVEKFCYKWTISNFSFCMGGIQRRITSPVFSSEENKEVAWCLRVYPKGADKESKDYLSVYLVLLSHLQSPVWAKFKFWIINSQGEKYQKTKSPIVECFLTYEQSGFKKFLPRDLLLSHRNCLLPEDQLTICCKVTILGRKYNMPSQNITPAIKDPRHLLTDDLGELWENSLFTDCCLLVAGHEFRAHKAILAARSPVFRAMFEHEMKESLKTPIKIHNLNPQVFKEMMSFIYTGKAPYLHSHSMACDVLPAADKYGLVSLKVLCEDAFCRNLSVKNATHTLILADLHSTEKLKTQALDFIAYYASEVCETSEWKSMVESHPHLVAEAFQSLASAQCSFLEPKVISGSNQL
What are the official names of this protein?
TD and POZ domain-containing protein 1-like.
What is the protein family that this protein belongs to?
Belongs to the Tdpoz family.
Protein: RL5_PSEE4
Sequence: MARLKEIYRNEIAPKLKEELKLSNVMEVPRVTKITLNMGLGEAIGDKKVIEHAVADLEKITGQKPVVTFARKSIAGFKVREGWPIGVKVTLRRDKMYEFLDRLLAISLPRVRDFRGLNAKSFDGRGNYSMGVKEQIIFPEIDYDKIDALRGLDITLTTTARSDDEGRALLRAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS13_CANAL
Sequence: MGRMHSSGKGISSSALPYSRNAPSWFKLSSDDVVEQIIKYARKGLTPSQIGVILRDAHGVSQAKVVTGNKILRILKSNGLAPEIPEDLYYLIKKAVSVRKHLEKNRKDKDSKFRLILIESRIHRLARYYRTVAVLPPNWKYESATASALVA
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RL24_METVA
Sequence: MVLTNSKQPRKQRKALYNAPLHLRNSVMSAMLSKALKEKYGKNALPVKKGDTVKVLRGSFKGIEGEVSKVNYSGYKIIVEGVVNKKQDGKETPYPIHPSNVMITKMEDSDEKRFKTSNK
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MON1_CRYNB
Sequence: MTSESEPNTSLPFSPIQQTLPATPSRSTSQVSMVSAEALLSHSSPTKQLTPSHRSSLPSALPYNTLLNAPAGSPALRARASTASSSRAPSVLDDARVEHNDSETQVLEITPPMDNYELDGGSDHTSLPSDASSIKGKEKQRSNDRNEIETVGAGGEMALPSGDARKGLKELVRRSTTADKGYGGHDHRRLSEKLSQTDENLQILITQSDKMSYSPRLYYVLTNAGKPVFCSHTRPSEDDVTNLMGVAQALISIFADDDDRLRYIIKGNHRVAFLLKAPLYLFCVSDWGEPEHVLRLQLEYIHLQILSVVSSTQLLRLFQRRSNADLSTLLEGTEPFLSNLIDCSQYDFSFLTSTLQPLRMAPALRDTSAAALMPPSKFKDLLYVLLIAGGHIVTVLRPRKHSIHPSDLHLLLNTIASSSALRTTETWLPICFPKFNPSGFVHAYISYVLEDVGLVFVSADREAFEDLRVWKDMVLEKLEQDKTLSRIQEAIPLHPYTISSVGCPGLRHFIYKSRQHVQITQPIWEAPYEDGSTNQKRLVTTYQKLHDAVHAKSGQASALKLVYISTEHEACLVWATKPFELYITVSPQLSKSAVVAAANNVAKWVLAEEGRIFLKDAPVF
What is the function of this protein?
Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
What are the official names of this protein?
Vacuolar fusion protein MON1.
What is the protein family that this protein belongs to?
Belongs to the MON1/SAND family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: PSBY_SPIOL
Sequence: MAATMATTMAVLNTKCLTLNTNKTTSTSPKPTSKPISLSPLGLSNSKLPMGLSPIITAPAIAGAVFATLGSVDPAFAVQQLADIAAEAGTSDNRGLALLLPIIPALGWVLFNILQPALNQINKMRNEKKAFIVGLGLSGLATSGLLLATPEAQAASEEIARGSDNRGTLLLLVVLPAIGWVLFNILQPALNQLNKMRSQ
What is the function of this protein?
PSBY-1 and -2 are manganese-binding polypeptides with L-arginine metabolizing enzyme activity.  They are a component of the core of photosystem II.  They have also a minor catalase-like activity since they cause evolution of oxygen from hydrogen peroxide in a reaction stimulated by manganese.
What are the official names of this protein?
Photosystem II core complex proteins psbY, chloroplastic, L-arginine-metabolizing enzyme, L-AME.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: GLYA_SYNS9
Sequence: MSQVSERAINAGLASADPEISRLIDQERHRQETHLELIASENFASQAVMQAQGSVLTNKYAEGLPAKRYYGGCEHVDAIETLAIERAKQLFDAAWANVQPHSGAQANFAVFLALLKPGDTIMGLDLSHGGHLTHGSPVNVSGKWFNVVQYGVDPTTQRLDMEAIRKLALEHKPKLIVCGYSAYPRTIDFAAFRSIADEVGAFLLADMAHIAGLVAAGVHPSPVPHCDVVTTTTHKTLRGPRGGLILCRDAEFAKKFDKAVFPGTQGGPLEHVIAAKAVAFGEALQPSFKTYSQQVVANAGALAEQLISRGINVVSGGTDNHVVLLDLRSIGMTGKVADLLVSDVHITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDVDAFREVADVIADRLHHPEDDAIRQRCLERVSILCSRFPLYADSKEPALV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_REOVD
Sequence: MSSMILTQFGPFIESISGITDQSNDVFEDAAKAFSMFTRSDVYKALDEIPFSDDAMLPIPPTIYTKPSHDSYYYIDALNRVRRKTYQGPDDVYVPNCSIVELLEPHETLTSYGRLSEAIENRAKDGDSQARIATTYGRIAESQARQIKAPLEKFVLALLVAEAGGSLYDPVLQKYDEIPDLSHNCPLWCFREICRHISGPLPDRAPYLYLSAGVFWLMSPRMTSAIPPLLSDLVNLAILQQTAGLDPSLVKLGVQICLHAAASSSYSWFILKTKSIFPQNTLHSMYESLEGGYCPNLEWLEPRSDYKFMYMGVMPLSAKYARSAPSNDKKARELGEKYGLSSVVGELRKRTKTYVKHDFASVRYIRDAMACTSGIFLVRTPTETVLQEYTQSPEIKVPIPQKDWTGPIGEIRILKDTTSSIARYLYRTWYLAAARMAAQPRTWDPLFQAIMRSQYVTARGGSGAALRESLYAINVSLPDFKGLPVKAATKIFQAAQLANLPFSHTSVAILADTSMGLRNQVQRRPRSIMPLNVPQQQVSAPHTLTADYINYHMNLSPTSGSAVIEKVIPLGVYASSPPNQSINIDISACDASITWDFFLSVIMAAIHEGVASSSIGKPFMGVPASIVNDESVVGVRAARPISGMQNMIQHLSKLYKRGFSYRVNDSFSPGNDFTHMTTTFPSGSTATSTEHTANNSTMMETFLTVWGPEHTDDPDVLRLMKSLTIQRNYVCQGDDGLMIIDGTTAGKVNSETIQNDLELISKYGEEFGWKYDIAYDGTAEYLKLYFIFGCRIPNLSRHPIVGKERANSSAEEPWPAILDQIMGVFFNGVHDGLQWQRWIRYSWALCCAFSRQRTMIGESVGYLQYPMWSFVYWGLPLVKAFGSDPWIFSWYMPTGDLGMYSWISLIRPLMTRWMVANGYVTDRCSTVFGNADYRRCFNELKLYQGYYMAQLPRNPKKSGRAASREVREQFTQALSDYLMQNPELKSRVLRGRSEWEKYGAGIIHNPPSLFDVPHKWYQGAQEAAIATREELAEMDETLMRARRHSYSSFSKLLEAYLLVKWRMCEAREPSVDLRLPLCAGIDPLNSDPFLKMVSVGPMLQSTRKYFAQTLFMAKTVSGLDVNAIDSALLRLRTLGADKKALTAQLLMVGLQESEADALAGKIMLQDVNTVQLARVVNLAVPDTWMSLDFDSMFKHHVKLLPKDGRHLNTDIPPRMGWLRAILRFLGAGMVMTATGVAVDIYLEDIHGGGRSLGQRFMTWMRQEGRSA
What is the function of this protein?
RNA-directed RNA polymerase that is involved in transcription and genome replication.  Following infection, it catalyzes the synthesis of fully conservative plus strands.  After core assembly, which consists in recruitment of one capped plus-strand for each genomic segments and polymerase complexes, the polymerase switches mode and catalyzes the synthesis of complementary minus-strands.
What are the official names of this protein?
RNA-directed RNA polymerase lambda-3, Lambda3, Lambda3(Pol).
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Found in the inner capsid (12 copies).
Protein: FND3B_HUMAN
Sequence: MYVTMMMTDQIPLELPPLLNGEVAMMPHLVNGDAAQQVILVQVNPGETFTIRAEDGTLQCIQGPAEVPMMSPNGSIPPIHVPPGYISQVIEDSTGVRRVVVTPQSPECYPPSYPSAMSPTHHLPPYLTHHPHFIHNSHTAYYPPVTGPGDMPPQFFPQHHLPHTIYGEQEIIPFYGMSTYITREDQYSKPPHKKLKDRQIDRQNRLNSPPSSIYKSSCTTVYNGYGKGHSGGSGGGGSGSGPGIKKTERRARSSPKSNDSDLQEYELEVKRVQDILSGIEKPQVSNIQARAVVLSWAPPVGLSCGPHSGLSFPYSYEVALSDKGRDGKYKIIYSGEELECNLKDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKSSLTLQWKAPIDNGSKITNYLLEWDEGKRNSGFRQCFFGSQKHCKLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVRAGITWVTLQWSKPEGCSPEEVITYTLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQYKFRLTASNTEGKSCPSEVLVCTTSPDRPGPPTRPLVKGPVTSHGFSVKWDPPKDNGGSEILKYLLEITDGNSEANQWEVAYSGSATEYTFTHLKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKEVHLEWDVPASESGCEVSEYSVEMTEPEDVASEVYHGPELECTVGNLLPGTVYRFRVRALNDGGYGPYSDVSEITTAAGPPGQCKAPCISCTPDGCVLVGWESPDSSGADISEYRLEWGEDEESLELIYHGTDTRFEIRDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSACLVLNWEEPCNNGSEILAYTIDLGDTSITVGNTTMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKTRPLPPLPPRLECAAAGPQSLKLKWGDSNSKTHAAEDIVYTLQLEDRNKRFISIYRGPSHTYKVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGNSCEILWETVPSMKGDPVNYILQVLVGRESEYKQVYKGEEATFQISGLQTNTDYRFRVCACRRCLDTSQELSGAFSPSAAFVLQRSEVMLTGDMGSLDDPKMKSMMPTDEQFAAIIVLGFATLSILFAFILQYFLMK
What is the function of this protein?
May be a positive regulator of adipogenesis.
What are the official names of this protein?
Fibronectin type III domain-containing protein 3B, Factor for adipocyte differentiation 104, HCV NS5A-binding protein 37.
What is the protein family that this protein belongs to?
Belongs to the FNDC3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NUSB_CORA7
Sequence: MTRPEPNFKRHTARYRARRRAADILFEAESRDVDPVAIVEDRVELARDPENGVAPIADYTREIVSGAAEELDAIDDAIARYLSSEWSLERIPAVDRAIMRVSVWEILFNADVPNATALVEGVELASEYSNDKAAPYIHAVLDDVIQAQSADSPMAPASAEEPAEPAETAETEGDTK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ACPS_BACC7
Sequence: MIVGIGIDIIELNRIEKMIDGKLKFMERILTESERNVAKGLKGSRLTEFVAGRFAAKEAYSKAVGTGIGKEVSFLDIEVRNDDRGKPILITSTEHIVHLSISHSKEFAVAQVVLESSSR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHOP1_HUMAN
Sequence: MSGCFPVSGLRCLSRDGRMAAQGAPRFLLTFDFDETIVDENSDDSIVRAAPGQRLPESLRATYREGFYNEYMQRVFKYLGEQGVRPRDLSAIYEAIPLSPGMSDLLQFVAKQGACFEVILISDANTFGVESSLRAAGHHSLFRRILSNPSGPDARGLLALRPFHTHSCARCPANMCKHKVLSDYLRERAHDGVHFERLFYVGDGANDFCPMGLLAGGDVAFPRRGYPMHRLIQEAQKAEPSSFRASVVPWETAADVRLHLQQVLKSC
What is the function of this protein?
Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho) (PubMed:15175005).  Involved in the generation of inorganic phosphate for bone mineralization (By similarity).  Acts in a non-redundant manner with PHOSPHO1 in skeletal mineralization: while PHOSPHO1 mediates the initiation of hydroxyapatite crystallization in the matrix vesicles (MVs), ALPL/TNAP catalyzes the spread of hydroxyapatite crystallization in the extracellular matrix (By similarity).
What are the official names of this protein?
Phosphoethanolamine/phosphocholine phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.
What are the subcellular locations of this protein?
Extracellular vesicle. Note=Localizes to special class of extracellular vesicles, named matrix vesicles (MVs), which are released by osteogenic cells.
Protein: SLYX_HAEIN
Sequence: MQIQQMLENRIEELEMKIAFQEQLLDELNHALVQQQFDIDKMQVQLRYMANKLKDFQSSNIASQSEETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.