PharMolix/UniProtQA huggingface dataset:
Protein: COMGG_BACSU
Sequence: MYRTRGFIYPAVLFVSALVLLIVNFVAAQYISRCMFEKETKELYIGENLLQNGVLLSIRHVLEERKGQEGTQQFLYGRVSYYIHDTSIKEQKEINLRVSTDSGTERTAQIVFDQKQKKLLRWTE
What is the function of this protein?
Required for transformation and DNA binding.
What are the official names of this protein?
ComG operon protein 7.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell membrane; Peptidoglycan-anchor. Secreted. Note=About half of pre-ComGG is present as a peripheral membrane protein and the other half as an integral protein. Upon (partial) processing ComGG is translocated to a position outside the membrane.
Protein: PPAX_BACC0
Sequence: MKINTVLFDLDGTLINTNELIISSFLHTLHTYYPNQYKREDVLPFIGPSLHDTFSKIDESKVEELITSYRQFNHDHHDELVEEYETVYETVQELKKQGYKVGIVTTKARQTVEMGLKLSKLDEFFDVVVTIDDVEHVKPHPEPLQKALQLLGAKPEEALMVGDNHHDIVGGQNAGTKTAAVSWTLKGRAYLEAYKPDFMLDKMSDLLPILSDMNRS
What is the function of this protein?
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P.  Might play a role in controlling the intracellular pyrophosphate pool.
What are the official names of this protein?
Pyrophosphatase PpaX.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PpaX family.
Protein: ZN440_HUMAN
Sequence: MDPVAFKDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSLGKRWKDQNIEYEHQNPRRNFRSLIEEKVNEIKDDSHCGETFTPVPDDRLNFQEKKASPEVKSCESFVCGEVGLGNSSFNMNIRGDIGHKAYEYQEYGPKPCKCQQPKKAFRYRPSFRTQERDHTGEKPNACKVCGKTFISHSSVRRHMVMHSGDGPYKCKFCGKAFHCLRLYLIHERIHTGEKPCECKQCGKSFSYSATHRIHKRTHTGEKPYEYQECGKAFHSPRSYRRHERIHMGEKAYQCKECGKAFTCPRYVRIHERTHSRKNLYECKQCGKALSSLTSFQTHVRLHSGERPYECKICGKDFCSVNSFQRHEKIHSGEKPYKCKQCGKAFPHSSSLRYHERTHTGEKPYECKQCGKAFRSASHLRVHGRTHTGEKPYECKECGKAFRYVNNLQSHERTQTHIRIHSGERRYKCKICGKGFYCPKSFQRHEKTHTGEKLYECKQRSVVPSVVPVPFDIMKGLTLERSPINASNVGKPSELCQSFECMVGLTLKRNPMSVSNDGKPSDLPHTFEYVVGHTMERSPMHVRNVGNPSDLPRTFEFMKGHKHT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 440.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KNOS9_ORYSJ
Sequence: MESFASLAGGGSSSTTARLPELIPPENPDRISPPPLLYQLLAGSASSARHGHGHHHGGGGGAAAAAVQGLQVSPAGAEAAMKAEIMSHPQYSALLAAYLGCKKVGAPPDVLTKLTAVPAAQQQLDAADGHPRRRHEPRRDDDVPDHQLDQFMHADEVQGGAGAADPGSRGVLQLDSIADSNCEGTGSSEEEQDTSCPEAEEIDPSDKQLKHQLLMKYGGSLGDLRQAFSKRTKKGKLPKEARLKLLHWWELHYDKWPYPSEVEKMTLAQTTGLDQKQISNWFINQRKRHWKPTPVAGMTFPTVEAAGGGFRHSGHDGGLAAAAAAAALPLYMGSWPFVVDGMYRLGS
What are the official names of this protein?
Homeobox protein knotted-1-like 9.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SCAM1_ORYSI
Sequence: MAGRYDSNPFEEDDVNPFSEQARGKAGGQPSYGGGAFYMPNPRNVPSMSSNSRLSPLPPEPAAFGATVDIPLDSSKDLKNREKELQAREAELNKREKELKRREEAAARAGIVIEEKNWPPFLPLIHHDITNEIPSHLQRMQYVAFASFLGLACCLFWNVIAVTSAWVKGEGVKIWLLAIIYFISGVPGAYVLWYRPLYNAMRTDSALKFGLFFLVYLFHILFCVFSAVAPPVVFEGKSLAGILPAIDLISKNALVGIFYFVGFGLFCVESLLSIWVIQQVYMYFRGSGKAAEMKRDATRGAMRAAF
What is the function of this protein?
Probably involved in membrane trafficking.
What are the official names of this protein?
Putative secretory carrier-associated membrane protein 1, Secretory carrier membrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Protein: LACB_STAA3
Sequence: MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPIFGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGRIIGELLMCDIIDAFINAEYKPTEENKKLIAKIKHLETSNADQADPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: PAU9_YEAST
Sequence: MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIRAHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRLKPAISSALSKDGIYTIAN
What are the official names of this protein?
Seripauperin-9.
What is the protein family that this protein belongs to?
Belongs to the SRP1/TIP1 family. Seripauperin subfamily.
Protein: FABH_LACDA
Sequence: MTYARIAKSSRYLSEFAVSNDDLSQIMETSDEWIKTRTGISSRRISQQENTSDLAIQVAKQLLAGEDPAGVDLIIVATMSPDAYTPATAALVQAAVGAENAACFDLSAACSGFVYALDVAEKMLRRPGGMALVIGAETLSKLVDWQDRTTAVLFGDGAGGVLVKNDALEPHFLASQLKSYGHLAKFLSAGQTSPQPFPGPVTDLAPFKMNGREVYKFATHKVPEVITACLEEAGVGLAEVDLFLLHQANYRIVKQVARRLDLPEEKFPCNIAEYGNTSAASEAILLAELAEEGKAQAGDLVVLAGFGGGLTAAAQLVRL
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOXA1_HUMAN
Sequence: MATLGHTFPFYAGPKPTFPMDTTLASIIMIFLTALATFIVILPGIRGKTRLFWLLRVVTSLFIGAAILAVNFSSEWSVGQVSTNTSYKAFSSEWISADIGLQVGLGGVNITLTGTPVQQLNETINYNEEFTWRLGENYAEEYAKALEKGLPDPVLYLAEKFTPRSPCGLYRQYRLAGHYTSAMLWVAFLCWLLANVMLSMPVLVYGGYMLLATGIFQLLALLFFSMATSLTSPCPLHLGASVLHTHHGPAFWITLTTGLLCVLLGLAMAVAHRMQPHRLKAFFNQSVDEDPMLEWSPEEGGLLSPRYRSMADSPKSQDIPLSEASSTKAYCKEAHPKDPDCAL
What is the function of this protein?
May be required for the maturation and the transport from the endoplasmic reticulum to the plasma membrane of functional DUOX1.
What are the official names of this protein?
Dual oxidase maturation factor 1, Dual oxidase activator 1, Numb-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the DUOXA family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UVRB_SYNJA
Sequence: MSEFQLVSSYQPTGDQPKAIAGLVKSILEGHRFQTLLGATGTGKTFTIAHTIQQVGRPTLVMAPNKTLAAQLCNELRELFPYNAVEYFISYYDYYQPEAYVPSTDTYIAKSSSINDEIDMLRHSATRSLFERRDVIVVASVSCIYGLGMPEEYLKASIPFQVGQEINQREVLRDLAGIQYERNDLELARGRFRVKGDVLEIVPAYEDRVIRIEFFGDEIEAIRLIDPVTGEILTSLSALRVYPARHFVTPEAQLQQAILNIEQELEEQLAFFRKQGKLLEAQRLEQRTRYDLEMLREVGYCNGIENYSRHLTGRKEGEPPACLVDYFKANDWLLVVDESHVTVPQIRGMYNGDRARKQVLVDHGFRLPSALDNRPLKAEEFWAKVHQCVFVSATPGNWELEQSGAQFETVVENGKTLKFYVPGTGRVIEQVIRPTGVVDPEVHVRPTAGQVEDLLGEIYLRLERSQQGLPERVIVTTLTKRMAEDLTEYLQERGIRVRYLHSEISSIERIEILQDFREGAFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRAERSLIQMIGRAARNVRGTVVMYADTLTGSMARAIAETQRRREIQLQYNRQHNITPKPIIKKNSNAILSFLAISRKLNSQDLEKAFPVADEIPLSEIPELIGQLELKMKAAAKNLEFEEAAQLRDQIKKLRQRLLGHHQST
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX8B_ATEBE
Sequence: MLSLRPALRLLQAPLRCWAVPKAHVSAKPAETPTSPAEQAVGLSFIFITFLGPAGWILSHVENYKKRPRA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8B, mitochondrial, Cytochrome c oxidase polypeptide VIII-heart, Cytochrome c oxidase subunit 8-1, Cytochrome c oxidase subunit 8H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PURA_PSEFS
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEHAAAVVRYQGGHNAGHTLVIDGEKTVLHLIPSGVLREGVQCLIGNGVVVAPDALLREITKLEEKGVPVRERLRISPSCPLILSFHVALDQAREKARGELKIGTTGRGIGPAYEDKVARRGLRVGDLLNMPRFEDKLRELVDYHNFMLVGYYKEPAIEFEKTLAECKEYAELLKPLMLDVTAELHDLRRAGKDIMFEGAQGSLLDIDHGTYPYVTSSNTTAGGVATGSGVGPMFLDYILGITKAYTTRVGSGPFPTELFDEVGAHLAKQGHEFGATTGRARRCGWFDAVILRRAIDVNSISGICFTKLDVLDGLETINICVGYKDADGNDVAPTDADSYVGLQPVYEEVPGWTESTVGAKTLEELPANARAYIKRVEALIGAPIDIISTGPDRNETIVLRHPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_STRE4
Sequence: MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GLGC_CLONN
Sequence: MIKKEMLAMILAGGQGTRLKILTKNNAKPAVPFGGKYRIIDFTLSNCSNSGIDTIGVLTQYEPHILNSHIGIGSPWDLDRKRGGVSILPPHMRNDGGNWYMGTADAIYQNIMFIDKYDPEYILVLSGDHIYKMDYSKMLQFHKEKNSDATIAVIDVPIEEASRFGIMNTNDDDKIYEFEEKPEQPKNNKASMGIYIFNWKILKEFLIEDSELEDSDHDFGKNIIPSLLDSGYNLYAYSFNGYWKDVGTIESLWQANMDLLDTKNPLDIYNKNWKIYSVSPSKPPQYTGPNAIIQNSLVVEGCAVFGKIQNSVLFPEVEVGSNSIIQDSVIMSNVKIGQNVIIRKCIIGSNTIIENNSVIGNSDDITVIGDGEKIKTNSIIKN
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: UVRB_CLOPS
Sequence: MGEFKIQSKFKPTGDQPKAIDTLVQSIENGNRGQTLLGVTGSGKTFTMANIIERTQKPTLILAHNKTLAAQLCAEFKEFFPDNIVEYFVSYYDYYQPEAYVPQTDTFIEKDASINDEIDKLRHSATSALLERRDVIIVASVSCIYGLGNPEEYKKLTISLRPGMIKDRDEVIKKLIEIQYERNDIDFARGTFRVRGDNLDIIPSSSSSKGIRIEFFGDEIDRIREFDVLTGNIIGERQHVSITPASHFAASEETLEKSISIIEDELEDRLKVLTAEDKILEAQRLKQRTNYDIEMIREMGYCQGIENYSRILDGRMPGTPPQTLLDYFPEDFLMFIDESHVTLPQVRAMYAGDRSRKTSLVEFGFRLPCAFDNRPLKFSEFESKINQVVFVSATPGEYELDHSEIVAEQIIRPTGLLDPVIEIRPIKGQIDDLYGEIQRTVQRGFRVLITTLTKRMAEDLTKYLKDLNVKATYMHSDIDTLERMKIIRELRLGEVDVLIGINLLREGLDIPEVALVAILDADKEGFLRSETSLIQTIGRAARNSESKVIMYADNITKSMDKSIKETERRRVIQMEYNEEHNITPTTVIKGVRDIIEATKVSEEKENYESEVKKAAKKDIPIEKLIEQYEEEMKEAAKNLQFERAAELRDIIKDLKENSK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_ASFP4
Sequence: MLNHFPGHCSNNIFCFPPIESETKSGKKASWIICVQVVQHNTIIPITDEMFSTDVKDAVAEIFTKFFVEEGTVRISKMTRITEGKNLGKKNATTVVHQAFKDALSKYNRHARQKRGAHTNRGMIPPMLVKYFNIIPKTFFEEETDPIVQRKRNGVRAVACQQGDGSILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDGELYLHRKPLQWIAGQANAKTDSSELHFYVFDCFWSDQLQMPSNKRQQLLTNIFKQKEDLTFIHQVENFSVKNEDEALRLKAQFIKEGYEGAIVRNVNGPYEPGYNNYHSAHLAKLKPLLDAEFILVDYTQGKKGKDLGAILWVCELPNKKRFVVTPKHLTYADRYALFQKLTPALFKKHLYGKELTVEYAELSPKTGIPLQARAVGFREPINVLEII
What is the function of this protein?
Very low-fidelity DNA ligase that seals nicks in double-stranded DNA during DNA repair (By similarity).  Together with the viral repair DNA polymerase X, fills the single nucleotide gaps generated by the AP endonuclease (By similarity).  It is not essential for viral replication and recombination (By similarity).  Displays a very low adenylation activity towards DNA with 3'-dideoxy- or 3'-amino-terminated nicks compared to regular nick DNA (By similarity).
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with the viral nucleoid.
Protein: TMM69_MOUSE
Sequence: MLHFIQKVSGASSKMLKNPFTVRLGAGRIDILSLKTCLLQNFSSLPPRTWLSPSFQVCMRKIQCYHVSPCNFKKQKAVLPPKKRSTITYLLDSPKPALYITLAGLIPFTAPPLLMVITKSYIPVLAFTQMAYGAGFLAFLGGIRWGFVLPESSPAKPDYINLASSMSPILFSWAAILFSERLNEAIVTLIIGLGIALHNELFLLPHYPNWFKALRIVSTLVAFISFVVTLILENIYPEKGPKRPD
What are the official names of this protein?
Transmembrane protein 69.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COX2_CAEEL
Sequence: MNNFFQGYNLLFQHSLFASYMDWFHSFNCSLLLGVLVFVTLLFGYLIFGTFYFKSKKIEYQFGELLCSIFPTIILLMQMVPSLSLLYYYGLMNLDSNLTVKVTGHQWYWSYEYSDIPGLEFDSYMKSLDQLSLGEPRLLEVDNRCVIPCDTNIRFCITSADVIHAWALNSLSVKLDAMSGILSTFSYSFPMVGVFYGQCSEICGANHSFMPIALEVTLLDNFKSWCFGTME
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CLPX_MAGSA
Sequence: MTKSTSGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKTHLVRSRDGVPTPKDICQVLDDYVIGQSHAKKVLSVAVHNHYKRLQHGGKNNEVELAKSNILLIGPTGCGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAAEYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIIGSRGRGTSIGFGADVRGPDERRTGEILREVEPEDLLKFGLIPEFVGRLPVLATLEDLDVDALIDILSKPKNALVKQYQRLFEMEDTRLAFSDDALKAIAEKAIARKTGARGLRSIMETILLDTMFDLPGLDAVDEVVINKEVVEGRAKPLYIYAERREDVGSSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CAMP_NOMCO
Sequence: MKTQRDSPSLGRWSLVLLLLGLVMPLAIVAQVLSYQEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARDSFDISCDKDNRRFALPGNFFRKAREKIGKEFKRIVQRIKDFLQHLVPRTEA
What is the function of this protein?
Exhibits antimicrobial activity against E. coli and B. megaterium (in vitro).
What are the official names of this protein?
Cathelicidin antimicrobial peptide.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RMI1_ARATH
Sequence: MRRRRLQLRYSSDEEEEDETGTSGVGDSVQSFGIASSIQPETSVSSNSNPNPGERIAISEVEIIDVFGNPQPTPPDSSIPTPYPVYPSESVSGNDYESPISEVLSRMGIKLKREWWVSCLSGLETSIPQFSYLDVAAKAKHCFEQFMFFDMNLCGGGVLPPNVASMNRIELAGPFVLQVDEIVNIGCPLKGRYENANAGLKRCLKLSMTDGVQRVFGMEYRPIKDLQVLAPAGLKIVVSSVQVRHGLLMLVPEIVEVLGGMVEELEEARKRLVVEVNKPPRGKRTRVGVVPSLTTRATLAAWSLNGNDTGNHVHDTGNHVNSSASGNASHTQANQGIPVHVTRTHNSSRAMDEPLASTNVGATVSRVEHMQIDTASAHGERTFSDIHSTSSNIHRAASTAGTGTSCSGACSGARSFANNVGGNSLDQTSNVTSFVEEMHIDTGRVRDTTTHIYGSDSGGVAAEFSNMVVDLEGPSVLSTNTEKPFTYLAELSQKWAVMKDTIHFVQGRIKCFLTGVKKFQFKQQSTYELLCYVDDGSLICEILLHNDVVQKRIGHSSMEVTAALSSSAPTSLNAMMKEKLKRFQLFLADFEGIMVVEMNRSSQYPVAIEMNQGCSLTDARLLLDRIKSSSRTSSSLNPVVVLSP
What is the function of this protein?
Essential component of the RMI complex, a complex that plays an important role in the resolution step of homologous recombination, in a process called Holliday Junction dissolution, to limit DNA crossover formation in cells.  Together with TOP3A, is essential for the resolution of meiotic recombination intermediates, a step that prevents entanglement of the parental chromosomes.
What are the official names of this protein?
RecQ-mediated genome instability protein 1, BLM-associated protein of 75 kDa homolog, BLAP75.
What is the protein family that this protein belongs to?
Belongs to the RMI1 family.
Protein: AQP4_BOVIN
Sequence: MSDRPAARRWGKCGPLCTRESIMVAFKGVWTQTFWKAVTAEFLAMLIFVLLSLGSTINWGGAEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRRISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTTVHGNLSAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGISVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVELKRRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDLILKPGVVHVIDIDRGEEKKGKDPSGEVLSSV
What is the function of this protein?
Forms a water-specific channel.  Plays an important role in brain water homeostasis and in glymphatic solute transport.  Required for a normal rate of water exchange across the blood brain interface.  Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways.  Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.  Plays a redundant role in urinary water homeostasis and urinary concentrating ability.
What are the official names of this protein?
Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endosome membrane. Cell membrane, sarcolemma; Multi-pass membrane protein. Cell projection. Note=Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane (By similarity). Detected on brain astrocyte processes and astrocyte endfeet close to capillaries (By similarity).
Protein: LPXB_BURCJ
Sequence: MPLPTNQLRLAMVAGEPSGDLLAASLLGGLRERLPESAQYYGIGGQRMIAQGFDSHWQMDKLTVRGYVEALGQIPEILRIRGELKRQLLAERPDAFIGVDAPDFNFSVEQAARDAGIPSIHFVCPSIWAWRGGRIKKIAKSVDHMLCLFPFEPAILDKAGVASTYVGHPLADDIPLEPDTHGARIALGLPADGPVIAVLPGSRRSEIALIGPTFFAAMALMQQREPGVRFVMPAATPALRELLQPLVDAHPQLALTITDGRSQVAMTAADAILVKSGTVTLEAALLKKPMVISYKVPWLTGQIMRRQGYLPYVGLPNILAGRFVVPELLQHFATPEALADATLTQLRDDANRRTLTEVFTEMHLSLRQNTAAKAAEAVVRVLEQRKGRA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: INDH_ARATH
Sequence: MATVALLRSLRRRELHAAHISAYKFSSASAGGRTTELRLHGVKDIIAVASGKGGVGKSSTAVNLAVALANKCELKIGLLDADVYGPSVPIMMNINQKPQVNQDMKMIPVENYGVKCMSMGLLVEKDAPLVWRGPMVMSALAKMTKGVDWGDLDILVVDMPPGTGDAQISISQNLKLSGAVIVSTPQDVALADANRGISMFDKVRVPILGLVENMSCFVCPHCNEPSFIFGKEGARRTAAKKGLKLIGEIPLEMSIREGSDEGVPVVVSSPGSIVSKAYQDLAQNVVKGLKELRENPDNEIQMKLNVPHSSHSS
What is the function of this protein?
Essential during early vegetative growth (PubMed:24179128).  Required for the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) (PubMed:24179128).  Involved in mitochondrial translation activity (PubMed:24179128).  May deliver of one or more Fe-S clusters to complex I subunits (By similarity).
What are the official names of this protein?
Iron-sulfur protein required for NADH dehydrogenase, mitochondrial, IND1 homolog, IND1-like protein, Nucleotide-binding protein-like.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family.
What are the subcellular locations of this protein?
Mitochondrion matrix.