PharMolix/UniProtQA huggingface dataset:
Protein: HRCA_NATTJ
Sequence: MSLNWRKQKILKTIISDYIKRAEPVGSRTLTKRYEFDLSPATIRNEMADLEDMGFLEQPHTSAGRIPTERGYRFFVDELITRCLSVPQQELLLKKLTKFKALEINEIVQVTARALAEMTDYTSLVLGPQTSKSAFQEIQVFPIDQQRVLMVLTTDTGIIESKPVPVSGNLSKQELSNIVQHLNKRLKGLTIDDITPSLLKELRTDLIKEVDLVEKAMHILADSFRHSSANVALGGTKNILNQPEFNDLKKVKELLSFFENEEVLAELLSESEGIVVRIGKENPRDEVKDCSLVTASYELNGRPLGTIGVLGPTRMDYSRVIAIVAQIANELTMALDKKKITEE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: RNH2_ANADE
Sequence: MRPEDLARLSVAELRTRLLDRGEALGDACEAALEADPRAGAREVLRLVRKRRRENRAEGQRLRHLLRYEAELWERGLVHVAGVDEAGMAPLAGPVVAGACVLPRDYRPRGIDDSKQLDRAERERLAEDIKRNAVCWAVARAEVEEIDRLNVYWAGMLALRRAVDGLSARPEHLLVDARKLPDLPFPQTPIVHGDALSLTIAAASILAKTARDALMAELDLAHPGYGFARHKGYPTAEHFDALGRLGACPIHRRSFAPVRVALGLEPAQGDLFALAEAAVAEDD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHD_SALPB
Sequence: MENIQKLIARYPLVEDLVALKETTWFNPGATSLAQGLPYVGLTEQDVNAAHDRLARFAPYLAKAFPQTAAAGGMIESDVVAIPAMQKRLEKEYGQTIDGEMLLKKDSHLAISGSIKARGGIYEVLTHAEKLALEAGLLTTDDDYSVLLSPEFKQFFSQYSIAVGSTGNLGLSIGIMSACIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEDDYGVAVEQGRKAAQSDPNCFFIDDENSRTLFLGYAVAGQRLKAQFAQQGRVVDASHPLFVYLPCGVGGGPGGVAFGLKLAFGDNVHCFFAEPTHSPCMLLGVYTGLHDAISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGLYTLDDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRICAAAAYQQRHGFSQTQLGNATHLVWATGGGMVPEDEMEQYLAKGR
What are the official names of this protein?
D-serine dehydratase, D-serine deaminase, DSD.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family. DsdA subfamily.
Protein: LPTD_PSEAB
Sequence: MAVKSLVFRRKFPLLVTGSLLALQPVAALTVQAADQFDCKVSATGGWDCSPLQNANANLPPRPAHTATSVSTAAAGSSVSGSGGETVEAEPTQRLVTESGGRALRSRSADYSHLDWIPREKLTAAQLAEIGPYCGGSYIEPVRPGMDDGAPSDESPTYVSAKASRYEQEKQIATLAGDVVLRQGSMQVEGDEANLHQLENRGELVGNVKLRDKGMLVVGDHAQVQLDNGEAQVDNAEYVIHKAHARGSALYAKRSENAIIMLKDGTYTRCEPSSNAWTLKGNNVKLNPATGFGTATNATLRVKDFPVFYTPYIYFPIDDRRQSGFLPPSFSSTSDTGFTLVTPYYFNLAPNYDATLYPRYMAKRGMMLEGEFRYLTHSSEGIVNAAYLNDKDDHREGFPDYSKDRWLYGLKNTTGLDSRWLAEVDYTRISDPYYFQDLDTDLGVGSTTYVNQRGTLTYRGDTFTGRLNAQAYQLATTTDVTPYDRLPQITFDGFLPYNPGGMQFTYGTEFVRFDRDLDENIYFNDDGSIRGKRPDASLQGLARATGDRMHLEPGMSLPMTRSWGYVTPTLKYLYTKYDLDLDSQGKTDLNKRDESFDSNQDRSLPLVKVDSGLYFDRDTTFAGTPFRQTLEPRAMYLYVPYKDQDSLPVFDTSEPSFSYDSLWRENRFTGKDRIGDANQLSLGVTSRFIEENGFERASISAGQIYYFRDRRVQLPGLTEKDLKRLNLDPSGLDNDSWRSPYAFAGQYRFNRDWRINSDFNWNPNTSRTESGSAIFHYQPEVDPGKVVNVGYRYRADARRFDSSRGTFRYGNEDDIIKQHDFSVIWPLVPQWSVLARWQYDYNKNRTLEAFGGFEYDSCCWKLRLINRYWLDVDDDAFLVQSEKADRGIFLQIVLKGLGGIVGNKTEMFLDKGIQGYRQREDQAM
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CLPS_ERWT9
Sequence: MGKTNDWLNFEQLADDKVREELKPPSMYKVILNNDDFTPMEFVIDVLQKFFSYDIERATQLMLTVHYQGKAICGVFTAEVAETKVAHVNKYARDNEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RS28_CANGA
Sequence: MDNKTPVTLARVIKVLGRTGSRGGVTQVRVEFLEDTSRTIVRNVKGPVRENDILVLMESEREARRLR
What are the official names of this protein?
40S ribosomal protein S28.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: RS12_STAA3
Sequence: MPTINQLVRKPRQSKIKKSDSPALNKGFNSKKKKFTDLNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RECR_RALSO
Sequence: MMRGGPGTPSALQMLIEALRVLPGVGPKSAQRMAYHLLQHDREGASRLAEALAEAAESIHHCSRCNTFTEQDVCETCLDPRRDASVLCVVETPADQMMIEQTLTYRGQYFVLMGRLSPLDNIGPKEIHLERLLARATDPALGGPCAEVILATNFTSEGEATAHYIGEMLKARGIKVSRLARGVPVGGELEYVDAGTIARAVLDRRQL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TAL_DELAS
Sequence: MNQLDALRQYTTVVADTGDFHQLAQFQPRDATTNPSLILKAVQKPEYAPLMRATVAQYKGRSLDEVMDRMLVRFGCEILNTIPGRVSTEVDARLSFNTSATVARAERLIELYQAEGVHIDRVLIKIASTWEGIEAARQLELRGIHTNLTLLFSFCQAVACGQAKVQLISPFVGRIYDWYKKQAGAQWDEAAMAGANDPGVRSVRAIYEHYKHFGIATEVMGASFRNTGQIVALAGCDLLTIAPELLAQLGASDAPLSRALDPEAARTLELDPVHYDEAGFRLALNEDAMGTEKLAEGIRAFAADTRKLEALMQQAAD
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCS_AERPE
Sequence: MSSVLEMLWVEKYRPRSLDDIVDQKHVVERLKQFVKQRNMPHLLFAGPPGTGKTTAAHALAHDLFGENYRQYMLELNASDERGINVIREKVKEFARSRTPPEIPFKIVLLDEADNMTSDAQQALRRLMELYSSVTRFILIANYPSKIIDPIQSRCAFFRFQPLSKQDVIERLRYIAENEGVDYEEEALDAIYEISEGDMRKAINVLQAASYLGKVTVDAVYRVVGMAKPREVREMLATALKGDFTAARSLLRKIMIEYGMSGEDVARQIHRELFSTELKMPEELRVLAADYLGEVHYRLVEGSDDDIQLSAFLAWLTMMSRKLEV
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.
Protein: MDL4_PRUSE
Sequence: MEKSTMSAVVLVLNLLVLHLQYSEVHSLANTSSEHDFGYLKFVYNAVDLELEGSYDYIIVGGGTSGCPLAATLSANYSVLVLERGTIATEYPNTLTVDGFAYNLQQQDDGKTPVERFVSEDGIDNVRSRILGGTTIINAGVYARANESFYNNSGVEWDLDLVNEAYEWVEDAIVYKPSNQSWQSITGTAFLEAGVHPDNGFGLVHEEGTRLTGSTFDNSGTRHASDELLNKGDPDNLKVAVEAAVQKIIFSTESSGLTAVGVVYTDSNGTSHRALVSGKGEVILSAGTLGTPQLLLLSGVGPESYLTSLNISVVASHPYVGQYVNDNPRNFINILPPNPIEPSTVTVLGITSDFYQCSLSSLPFDTPPFSLFPTTSYPLPNQTFAHIVSKVPGPLSAGSLTLQSSSNVSVAPNVKFNYCSDPVDLTHCVSGMKKIGVFLSTDALKPYKVDDLPGIDGFNILGTPLPENQTDDAAFEKFCRDTVASYWHYHGGAIVGKVIDGNFRVTGINALRVVDGSTFPATPASHPQGFYLMLGRYVGTKIVQERSASGEAIHTSTFKPKLMDSLKSALSFAF
What is the function of this protein?
Involved in cyanogenesis, the release of HCN from injured tissues.  Catalyzes the stereospecific addition of HCN to a variety of aldehydes in vitro.  It is a major seed constituent, and could have the additional role of a storage form for reduced nitrogen (By similarity).
What are the official names of this protein?
(R)-mandelonitrile lyase 4, Hydroxynitrile lyase 4, (R)-oxynitrilase 4.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Note=Primarily found within protein bodies of the cotyledonary parenchyma cells, with lesser amounts within the procambium.
Protein: FLIC_BRUME
Sequence: MASILTNSSALTALQTLASTNKSLESTQNRISTGLRISEASDNASYWSIATSMKSDNKANSAVQDALGLGAGKVDTAYSAINKIRESVDDIKTKLVSAMGASTEDKGKIETEIKSIVANINSALSNANYAGSNLLNGPTTDLNVVASYNRSGNAVAVDKITVKATDTDAKTMVKDIVDAGFFTSASDDTAIGTALNTVETALASLATGAATLGAAKSQIDSQKSFLSGLQDSIEKGVGTLVDADMNKESARLSALQVQQQLGVQALSIANSSNQSILSLFRG
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella (By similarity).  The flagellum is required to cause a persistent disease in a murine model of infection.
What are the official names of this protein?
Flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: DIRA2_HUMAN
Sequence: MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM
What is the function of this protein?
Displays low GTPase activity and exists predominantly in the GTP-bound form.
What are the official names of this protein?
GTP-binding protein Di-Ras2, Distinct subgroup of the Ras family member 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Di-Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RL33_THEP3
Sequence: MRVKITLACTECKNRNYHTTKNKKNDPDRLELMKYCKFCKKHTLHRETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RAF1_SYNP2
Sequence: MIGQPQSPEYKLSPEETDALFRSLLHKEGTWVEWGVGCQQLQQSGHSAQEIFEQTGFQTAQQNMIIVAAQVYQSIASSGVPEDLLAYCRGPRSDVLYELRILSHSQRAIAAQVCQAKSLEFDGAKELARAMQEFARLPQIPDSFTEHPGDAVAYQAWRSAKQKKDLQDRTRLIAKGLKFAHSATARQKIEQLLSDLTTSPTKAAPLLPLYRYDEDTNVPLLIPVAGSLPLESDRLLSVPPLKQASPFNLVTVATATSLVPLPSWQNVLTAGDPVVIFHQTDQLPQPIPGKPEPVLILLDRQQTTWNDNSYFAVDADGKVELGWFAEAPIAKILGQVLLVMRPKKILDENNLREPWQMDD
What is the function of this protein?
Raf1 and RbcX are probably functionally redundant; it has been suggested they may cooperate.
What are the official names of this protein?
RuBisCO accumulation factor 1.
What is the protein family that this protein belongs to?
Belongs to the RAF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VA0D2_CHICK
Sequence: MPGYSEFYFNVDHGYLEGLVRGFKAGILTSADYVNLAQCETLEDLKLHLQTTDYGNFLANESGPLTISTIDDKLKTKLLTEFHYFRNHAFEPLTTFLNFITYSYMIDNIILLITGTLHQRPIAELVPKCHPLGSFEQMEAVSIASNPTELFNAILVDTPLAAFFQDCLSENDLDEMNVEIMRNKLYKSYLEAFYKFCEKQGGTTAEIMKPILEFEADRRAFIITINSFGTELSKEDREKLYPTCGKLYPEGLHLLANADDYEQVKCVADYYAEYKAVFEGVGNDSGEKTLEDAFFEHEIKLNVLAFNNQFHFGVFYAYIKLKEQECRNIVWIAECISQRHRTKINNYIPIF
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons.  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  May play a role in coupling of proton transport and ATP hydrolysis (By similarity).  Regulator of osteoclast fusion and bone formation (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit d 2, V-ATPase subunit d 2, Vacuolar proton pump subunit d 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: LEC3_CROVR
Sequence: DNNVLLTGDVIHTDNQLSYESAAFVMQGDCNLVLYNEAGGFQSNTHGRGVDCTLRLNNRGQLEIHSANSNTPVWVYPRSVNTVRGNYAATLGPDQHVTIYGPAIWSTPAAANIPRVRNVLFSSQVMYDNAQLATRDYSLVMRDDCNLVLTKGSKTNIVWESGTSGRGQHCFMRLGHSGELDITDDRLNTVFVSNTVGQEGDYVLILQINGQAVVYGPAVWSTAA
What is the function of this protein?
Mannose-specific lectin.  Has weak agglutinating activity towards trypsin-treated erythrocytes from rabbit but not from human (By similarity).
What are the official names of this protein?
Mannose-specific lectin 3.
Protein: DNLI_ASFWA
Sequence: MLNHFPGHCSNNIFCFPPIESETKSGKKASWIICVQVVQHNTIIPITDEMFSTDVKDAVAEIFTKFFVEEGTVRISKMTRVTEGKNLGKKNATTVVHQAFKDALSKYNRHARQKRGAHTNTGMIPPMLVKYFNIIPKTFFEEETDPIVQRKRNGVRAVACQQGDGSILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDGELYLHRKPLQWIAGQANAKTDSSELHFYVFDCFWSDQLQMPSNKRQQLLTNIFKQKEDLTFIHQVENFSVKNEDEALRLKAQFIKEGYEGAIVRNANGPYEPGYNNYHSAHLAKLKPLLDAEFILVDYTQGKKGKDLGAILWVCELPNKKRFVVTPKHLTYADRYALFQKLTPALFKKHLYGKELTVEYAELSPKTGIPLQARAVGFREPINVLEII
What is the function of this protein?
Very low-fidelity DNA ligase that seals nicks in double-stranded DNA during DNA repair (By similarity).  Together with the viral repair DNA polymerase X, fills the single nucleotide gaps generated by the AP endonuclease (By similarity).  It is not essential for viral replication and recombination (By similarity).  Displays a very low adenylation activity towards DNA with 3'-dideoxy- or 3'-amino-terminated nicks compared to regular nick DNA (By similarity).
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with the viral nucleoid.
Protein: SYFA_CHLCV
Sequence: MMIQEELEATKQQFCIELDQVHSSKDLFDLKVRYLGKKGLFRCFADKLRECPSDQKALMGASINACKTYIEDLIRDKNNAILLAEESAEFLKEKIDITLPGEPQCPGGKHIVKKVLDDVVDIFVHLGFCVREAPNIESEENNFSLLNFEENHPARQMHDTFYLDAKTVLRTHTSNVQVRELSRGEPPIKVVAPGLCFRNEDISARSHVIFHQVEAFYVDRNVTLSDLTEMLTEFYHTFFERKIELRLRHSYFPFVEPGIEVDVSCECQAAGCSLCKHTGWLEVAGAGMIHPQVLRNSGVDPETYTGYAVGMGIERLAMLKHGISDIRLFCENDLRFLQQFS
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLX_ECOL6
Sequence: MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADKARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDKLHALRYADSVSMTLSWQR
What is the function of this protein?
Catalyzes the epimerization of carbon 2' of the side chain of 7,8-dihydroneopterin triphosphate (H2NTP) to form 7,8-dihydromonapterin triphosphate (H2MTP).  Is required for tetrahydromonapterin biosynthesis.
What are the official names of this protein?
Dihydroneopterin triphosphate 2'-epimerase, D-erythro-7,8-dihydroneopterin triphosphate epimerase.
What is the protein family that this protein belongs to?
Belongs to the DHNA family.
Protein: ARGL1_XENTR
Sequence: MGRSRSRSSSRSKHAKSGKHNKKRSRSREKERVRKRSKSRESKRNRRRESRSRSRSNTASRRERERAASPPDRIDIFGRTVSKRSSLDEKQKREDEEKKAEYERQRRIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIADAQAKLAEEQLKIVEEQRKIHEERMKLEQERQRQQKEEQKIILGKGKSRPKLSFSLKSPD
What are the official names of this protein?
Arginine and glutamate-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the UPF0430 family.
Protein: PP4C_YEAST
Sequence: MMDLDKIIASLRDGKHIPEETVFRLCLNSQELLMNEGNVTQVDTPVTICGDIHGQLHDLLTLFEKSGGVEKTRYIFLGDFVDRGFYSLESFLLLLCYKLRYPDRITLIRGNHETRQITKVYGFYDEVVRKYGNSNVWRYCCEVFDYLSLGAIINNSIFCVHGGLSPDMTTVDEIRTIDRKQEVPHEGAMCDLLWSDPEDVDTWSLSPRGAGFLFGKREVDQFLEKNNVELIARAHQLVMEGYKEMFDGGLVTVWSAPNYCYRCGNVAAVLKIDDDLNREYTIFEAVQAQNEVGNAIIPTKKSQMDYFL
What is the function of this protein?
Forms the histone H2A phosphatase complex in association with the regulatory subunits PSY2 and PSY4, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process.  Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint.  PPH3 is directly involved in the dephosphorylation and activation of the transcription factor GLN3 in response to nutrient availability.
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 catalytic subunit, PP4C, Phosphatase PP2A-like catalytic subunit PPH3.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATZN_SYNY3
Sequence: MTQSSPLKTQQMQVGGMDCTSCKLKIEGSLERLKGVAEASVTVATGRLTVTYDPKQVSEITIQERIAALGYTLAEPKSSVTLNGHKHPHSHREEGHSHSHGAGEFNLKQELLPVLTAIALFTIAILFEQPLHNTPGQIAEFAVIIPAYLLSGWTVLKTAGRNILRGQIFDENFLMTIATLGALAIHQLPEAVAVMLFFRVGELFQEYSVGRSRRSIKALLEARPDTANLKRNGTVQQVSPETVQVDDLILVKPGEKVPLDGEILGGTSQVDTSALTGESVPGTVKPGDTILAGMINQSGVLTIRVTKLFSESSIAKVLDLVENASSKKASTEKFITQFARYYTPVIVFLSLAVALLPPLFIPGADRADWVYRALVLLVISCPCGLVISIPLGYFGGIGGAAKHGILIKGSTFLDSLTAVKTVVFDKTGTLTKGTFKVTQVVTKNGFSESELLTLAAKAESHSTHPIALSIREAYAQSIADSEVADYEEIAGHGIRAVVQNQVVIAGNDRLLHREKIDHDTCDVAGTVVHLAVDGRYGGYILIADEIKEDAVQAIRDLKRMGVEKTVMLTGDSEIVAQSVAQQIGLDAFVAELLPEEKVDEIEQLLDPSGKAKLAFVGDGINDAPVIARADVGIAMGGLGSDAAIETADVVLMTDAPSKVAEAIHVARKTRQIVVQNIVLALGIKALFIALGTIGLATLWEAVFADVGVALLAILNATRIAK
What are the official names of this protein?
Zinc-transporting ATPase, Zn(2+)-translocating P-type ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENO_BART1
Sequence: MTIIVDIIGREVLDSRGNPTVEVDVYLENGAFGRALVPSGASTGAHEAIELRDGDLRYQGKGVEKAVAAVNGEILEELGGRDARDQIAIDQAMIALDGTPNKARLGANALLGVSLAVAKAAADSLNLPLYRYIGGTQAHILPTPMMNIINGGVHADNLIDFQEFMIIPVGAPSVKEAIRYGAEIFHALKKRLKDAGYNTNVGDEGGFAPQFKSADQAIDFIMESIIACGYKPGEQIAIGLDCASTEFYKNGSYFYKGEGKCRNIAEQVDYLAQLVKSYPIVTIEDGMAEDDWEGWKLLTDTIGTKCQMVGDDLFVTNSARLRDGIKMGVGNSILIKVNQIGTLSETLDAVEVAHKAGYRAIISHRSGETEDSFIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEMLGSQARYAGDIYR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PITM3_HUMAN
Sequence: MAKAGRAGGPPPGGGAPWHLRNVLSDSVESSDDEFFDAREEMAEGKNAILIGMSQWNSNDLVEQIETMGKLDEHQGEGTAPCTSSILQEKQRELYRVSLRRQRFPAQGSIEIHEDSEEGCPQRSCKTHVLLLVLHGGNILDTGAGDPSCKAADIHTFSSVLEKVTRAHFPAALGHILIKFVPCPAICSEAFSLVSHLNPYSHDEGCLSSSQDHVPLAALPLLAISSPQYQDAVATVIERANQVYREFLKSSDGIGFSGQVCLIGDCVGGLLAFDAICYSAGPSGDSPASSSRKGSISSTQDTPVAVEEDCSLASSKRLSKSNIDISSGLEDEEPKRPLPRKQSDSSTYDCEAITQHHAFLSSIHSSVLKDESETPAAGGPQLPEVSLGRFDFDVSDFFLFGSPLGLVLAMRRTVLPGLDGFQVRPACSQVYSFFHCADPSASRLEPLLEPKFHLVPPVSVPRYQRFPLGDGQSLLLADALHTHSPLFLEGSSRDSPPLLDAPASPPQASRFQRPGRRMSEGSSHSESSESSDSMAPVGASRITAKWWGSKRIDYALYCPDVLTAFPTVALPHLFHASYWESTDVVAFILRQVMRYESVNIKESARLDPAALSPANPREKWLRKRTQVKLRNVTANHRANDVIAAEDGPQVLVGRFMYGPLDMVALTGEKVDILVMAEPSSGRWVHLDTEITNSSGRITYNVPRPRRLGVGVYPVKMVVRGDQTCAMSYLTVLPRGMECVVFSIDGSFAASVSIMGSDPKVRPGAVDVVRHWQDLGYMILYITGRPDMQKQRVVSWLSQHNFPQGMIFFSDGLVHDPLRQKAIFLRNLMQECFIKISAAYGSTKDISVYSVLGLPASQIFIVGRPTKKYQTQCQFLSEGYAAHLAALEASHRSRPKKNNSRMILRKGSFGLHAQPEFLRKRNHLRRTMSVQQPDPPAANPKPERAQSQPESDKDHERPLPALSWARGPPKFESVP
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes (in vitro) (By similarity).  Binds calcium ions.
What are the official names of this protein?
Membrane-associated phosphatidylinositol transfer protein 3, Phosphatidylinositol transfer protein, membrane-associated 3, PITPnm 3, Pyk2 N-terminal domain-interacting receptor 1, NIR-1.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein.
Protein: GBRA5_MOUSE
Sequence: MDNGMLSRFIMTQTLLVFCISMTLSSHFGFSQMPTSSVQDETNDNITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEAAKIKKKERELILNKSTNAFTTGKLTHPPNIPKEQPPAGTANAPTVSIKASEEKTAESKKTYNSISKIDKMSRIVFPILFGTFNLVYWATYLNREPVIKGATSPK
What is the function of this protein?
Ligand-gated chloride channel subunit which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain.  May be involved in GABA-A receptor assembly, and GABA-A receptor immobilization and accumulation by gephyrin at the synapse.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-5, GABA(A) receptor subunit alpha-5.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: ACCD_PROMH
Sequence: MSWIEKILNKSNITSSRKANIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRISARRRLETFLDTGSTTELGSELEPKDILKFRDSKKYKDRIAAAQKQTHEKDALVVMKGTLKEMPVVAASFEFAFMGGSMASVVGARFVRAVEQALEDNCPLICFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVMTDPTMGGVSASLAMLGDINVAEPKALIGFAGPRVIEQTVREKLPAGFQRSEFLLEKGAIDMIVRRPEMRDELAELLAKLTQYDLAKDEDELLGEEMIADDIESSDNEPEINIETNKKEDV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT12_MOUSE
Sequence: MAATVNLELDPIFLKALGFLHSKSKDSAEKLKALLDESLARGIDSSYRPTQKDVEPPKISSTKSLSIKQEPKTSSSLPSGSSNGKVLTAEKIKKEAEKRPADKMKDVTEGIDVPKKPRLEKPETRSSPITVQTSKDLSMADLSSFEETSADDFAMEMGLACVVCRQMTVASGNQLVECQECHNLYHQDCHKPQVTDKEVNDPRLVWYCARCTRQMKRMAQKTQKPPQKPAPTVVSVTPTVKDPLVKKPETKLKQETTFLAFKRTEVKPSTVISGNSSSNNVSSSVTSGLTGWAAFAAKTSSAGPSTAKLNSAAQNSSGKPAASSSNQKPVGLTGLATSSKGGIGSKIGSGNSTSPSVPLKPLPPLTLGKTGLSRSVSCDNVSKVGLPSPSSLVPGGSSQLSGNGNSATTGPSGSTTSKATSETSSSTSASLKGPTSQESQLNAMKRLQMVKKKAAQKKLKK
What is the function of this protein?
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 12, Int12, PHD finger protein 22.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 12 family.
What are the subcellular locations of this protein?
Nucleus.