PharMolix/UniProtQA huggingface dataset:
Protein: TGM1_HUMAN
Sequence: MMDGPRSDVGRWGGNPLQPPTTPSPEPEPEPDGRSRRGGGRSFWARCCGCCSCRNAADDDWGPEPSDSRGRGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESSDRITLELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGSAEDVAMQVEAQDAVMGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA
What is the function of this protein?
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.  Responsible for cross-linking epidermal proteins during formation of the stratum corneum.  Involved in cell proliferation (PubMed:26220141).
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase K, Epidermal TGase, Transglutaminase K, TG(K), TGK, TGase K, Transglutaminase-1, TGase-1.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: RECA_CUPNH
Sequence: MDDKKAGAGVSAEKQKALAAALSQIEKQFGKGSIMRLGDGEVEKDIQVVSTGSLGLDIALGVGGLPRGRVVEIYGPESSGKTTLTLQVVAEMQKLGGTCAFIDAEHALDVSYANKLGVNVGDLLISQPDTGEQALEITDALVRSGSIDLIVIDSVAALVPKAEIEGEMGDSLPGLQARLMSQALRKLTGTIKRTNCLVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSIKKGDDVIGNETKVKVVKNKVSPPFREAFFDILYGQGISRQGEIIDLGVDAKIVEKSGAWYSYNGDKIGQGKDNAREYLRENPDIADEIENKVRAALGVVAMNPTAAATPVAVED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPT2_BOVIN
Sequence: MKMSRLCLSIALLVLLGTLAASTPGCDTSNQAKAQRPDFCLEPPYTGPCKAKMIRYFYNAKAGFCETFVYGGCKAKSNNFRSAEDCMRTCGGAIGPRENL
What are the official names of this protein?
Spleen trypsin inhibitor I, SI-I.
What are the subcellular locations of this protein?
Secreted.
Protein: MINE_XANOP
Sequence: MGLLDFLKSKKNTAETAKNRLQIIIAQERNHRGGPDYLPLMQRELLEVIKKYVNIDADAVRVDLVKDGEHDVLDISVALPEDGDK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: HDHD3_MOUSE
Sequence: MAHRLQMRLLTWDVKDTLIKLRRPVGEEYASKARAHGVVVEDITVEQAFRQAYRAQSHNFPNYGLSRGLTSRQWWKDVVLHTFRLAGVPDAQAMTPVADQLYEDFSSPFTWQVLEGAEMTLKGCRKRGLKLAVVSNFDRRLEDILTGLGLREHFDFVLTSEAVGCPKPDPRIFREALQRACVEPAVAAHVGDSYLCDYQGSQAVGMHSFLVAGSEPLDSAVRDSVPKEHILPSLSHLLPALDLLEASSPMS
What are the official names of this protein?
Haloacid dehalogenase-like hydrolase domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: KS6B2_HUMAN
Sequence: MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR
What is the function of this protein?
Phosphorylates specifically ribosomal protein S6 (PubMed:29750193).  Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 (PubMed:29750193).
What are the official names of this protein?
Ribosomal protein S6 kinase beta-2, S6K-beta-2, S6K2, 70 kDa ribosomal protein S6 kinase 2, P70S6K2, p70-S6K 2, S6 kinase-related kinase, SRK, Serine/threonine-protein kinase 14B, p70 ribosomal S6 kinase beta, S6K-beta, p70 S6 kinase beta, p70 S6K-beta, p70 S6KB, p70-beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BIOB_ECO5E
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMSYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: LFTY1_HUMAN
Sequence: MQPLWLCWALWVLPLASPGAALTGEQLLGSLLRQLQLKEVPTLDRADMEELVIPTHVRAQYVALLQRSHGDRSRGKRFSQSFREVAGRFLALEASTHLLVFGMEQRLPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSARARVTVEWLRVRDDGSNRTSLIDSRLVSVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRFASQGAPAGLGEPQLELHTLDLGDYGAQGDCDPEAPMTEGTRCCRQEMYIDLQGMKWAENWVLEPPGFLAYECVGTCRQPPEALAFKWPFLGPRQCIASETDSLPMIVSIKEGGRTRPQVVSLPNMRVQKCSCASDGALVPRRLQP
What is the function of this protein?
Required for left-right axis determination as a regulator of LEFTY2 and NODAL.
What are the official names of this protein?
Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL6_HELPJ
Sequence: MSRIGKRIIEIPSSVQASVEGSKLLFKNNKEKHELETHNRVKITLENNQLSFQPVGEDAQFRAYWGTYGALANNIVIGLSAGFSKTLEVNGVGYKVALGHKTLDLSLGFSHPVKYPIPAGIEMVVEKNTITIKGSDKQQVGQVAAEIRSFRPPEPYKGKGVKYSNEVIIRKAGKTAKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RS12_NEIMA
Sequence: MPTINQLVRKGRQKPVYVNKVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTAGVKDRKQARSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: WDHD1_MOUSE
Sequence: MPATQKPMRYGHTEGHTEVCFDDSGSYIVTCGSDGDVRMWEDLDDDDPKSVNVGEKAFSCALKNGKLVTAVSNNTVQVYTFPEGVPDGILTRFTTNANHVVFNGAGNKIAAGSSDFLVKVVDVMDNSQQQTFRGHDAPVLSLSFDPKDIFLASASCDGTVRVWNISDQTCAVSWPVLQKSNDVVNAKSICRLAWQPKAGKLLAVPVEKSVKLYRRETWSNPFDLSDSSISQTLNIVTWSPCGQYLAAGAINGLIVVWNVETKDCMERVKHEKGYAICGLAWHPTCSRICYTDVEGNLGVLENVCDLSGKVSSNKVSSRVEKDYNDLFDGDDTSSAGDFLNDNAVEIPSFSKGIINEDDDNDDIMLAADHDLGDDENSVDVTMLKADLSHKEEGDDDQARSIHNLPLIRPQRPFYDGPMPTPRQKPFQSSSTPLHLSHRFMVWNSVGIIRCYNDDQDSAIDVEFHDTSIHHATHLLNAFNYTMGTLSHEAILLACESADELASKLHCLHFSSWDSSKEWMVDMPQNEDIEAICLGLGWAAAATTALLLRLFTIGGVQKEVFCLPGPVVSMAGHGEQLCIVYHRGTGFDGDQCLGVQLLELGRKKNQVLHGDPLPLTRKSYLTWLGFSAEGTPCYVDSEGCVRMLNRGLGNTWTPVCNIREHCKGKSDHYWVVGIHENPQQLRCIPCKGSRFPPTLPRPAVAILSFKLPYCQTSTEKGQMEEQFWHSVLFHNYLDYLAKNGYDYEESIKNQAVKEQQELLMKMLALSCKLEREFRCVELADLMTQNAVHLAIKYASRSRKLILAQKLSELAAEKAAELAETQSEEEKEEDFREKLNAGYSHTTTEWSRPRVRSQVEDAEDREDTVSEEKPESHNHGQNLFQSANSSDTPALKSGAVFSSSQGWVNPFKVVVSSKEPAVSANSTRSANILDSMNKSSRKSTSLNRMENNEKSPVIKPLTPKPRSKQASAASYFQKRTPQADKTEEVKENPKSSSSDAPAVCLQNSENQRPKTGFQMWLEENRSQILSDNPDISDETDIIKEGMIRFRVLSAEERKAWTNKAKGETASDGAEAKKRKRVVSEICETENQEETVKENLDLSKKQKALNLPANQKLSAFAFKQ
What is the function of this protein?
Core replisome component that acts as a replication initiation factor.  Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork.
What are the official names of this protein?
WD repeat and HMG-box DNA-binding protein 1, Acidic nucleoplasmic DNA-binding protein 1, And-1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: EFNA2_DANRE
Sequence: MELSLVVFTVVCWVSVWSDDRIISDRHAVYWNSSNSRFWQGEYTVAVSINDYLDVYCPYYESPQPHSRMERYILFMVNHDGYLTCEHRMRGFKRWECNRPQSPDGPLRFSEKFQLFTPFSLGFEFRPGHEYYYISSPHPNHAGKPCLKLKVYVKPTSSGYESPEPFLTDQSQRCGADGPCLAVLMLLLVFLLAGV
What is the function of this protein?
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  With the epha2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity).
What are the official names of this protein?
Ephrin-A2, ELF-1, EPH-related receptor tyrosine kinase ligand 6, LERK-6, ZfEPHL3.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: PANB_PYRHO
Sequence: MREITPKRIREMKGKEKITMITAYDYPSALLADKAGFDIVFIGDSLGMVVYGEPSTLNVTMEQMIFHTRAVAKAVKRALVLADMPFGSYEVSVEEGIKNAIKLVQAGADAVKIEGGYDHRKLVKKLVRIGIPVMGHTGLTPQRYLRLGGYRIMGGTEEEVEEILRDAKALEKAGAFAIVLEFVLADVAKLVTEEVSIPTIGIGSGPYVDGQVLVWHDVLGLYESSPPFAKRYANLKEEILRAISTFREEVKEGKFPGREHYWEFQDKEEFKRIKDNVMKKLNL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMCD1_HUMAN
Sequence: MAKVAKDLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS
What is the function of this protein?
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes.  Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters.  Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity).  Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
What are the official names of this protein?
LIM and cysteine-rich domains protein 1, Dyxin.
Protein: DRE2_LEIBR
Sequence: MSTPATTTQAFSLKTRQPIADEDALLTEEDRILKQATKGEDCTTRRRACKNCVCGRAELERKLEAEGKLPPEGITMPPGGCGNCAKGDAFRCANCPFLGQPAFDSTEDGKVKLNLTDDI
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.  Electrons are transferred from NADPH via a FAD- and FMN-containing diflavin oxidoreductase.  Together with the diflavin oxidoreductase, also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit.
What are the official names of this protein?
Anamorsin homolog, Fe-S cluster assembly protein DRE2 homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: DNLI_ASFK5
Sequence: MLNQFPGQLSNNVFCFPPIESETKSGKKASWIICVQVMHHNTILPITDEMFSTDVKDAVAEIFTKFFVEEGAVRISKTTRVTEGKNLGKKNATTVVHQAFKDALSKYNRHARQKRGAHTNRGMIPPMLVKHFNIIPKTFFEDETDPIVQRKRNGVRAVACQQGDGSILLYSRTEKEFLGLDNIKKELKQLYLFIDVRVYLDGELYLHHKPLQWIAGQANAKVDSSELHFYVFDCFWSDQLQMPSNKRQQLLTNIFKQKEDLIFIHQVENFSIKDEDEALRLKTQFIKEGYEGAIVRNANGPYEPGYNNYHSPHLAKLKPLLDAEFILVDYTQGKKGKDLGAILWVCELPNKKRFVVTPKHLTYADRYALFQKLTPALFKKHLYGKELTVEYAELSPKTGIPLQARAVGFREPINVLEII
What is the function of this protein?
Very low-fidelity DNA ligase that seals nicks in double-stranded DNA during DNA repair (By similarity).  Together with the viral repair DNA polymerase X, fills the single nucleotide gaps generated by the AP endonuclease (By similarity).  It is not essential for viral replication and recombination (By similarity).  Displays a very low adenylation activity towards DNA with 3'-dideoxy- or 3'-amino-terminated nicks compared to regular nick DNA (By similarity).
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
What are the subcellular locations of this protein?
Virion. Note=Found in association with the viral nucleoid.
Protein: CLPX_YERPY
Sequence: MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVSPHRDRSSLPTPHEIRHHLDDYVIGQEPAKKVLAVAVYNHYKRLRNGDTSNGIELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVIGQRINTGSGIGFGAVVKGQSEKATEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLSELSEDALIQILKEPKNALTKQYQALFSLEGVELEFRDEALTAIAKKAMARKTGARGLRSIVEGALLDTMYDLPSMDSVEKVVVDESVIAGQSAPMLIYGQPEAQASGE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: TSAD_CHLL2
Sequence: MNILGIETSCDETSAAVLLDGRIGSNVISSQRCHTSFGGVVPELASREHERTIVSIVNSAVTEANITKNELDCIAATAGPGLIGAVMVGLCFAEGMAFALGIPFVPVNHIEAHMFSAFIPESPEHKSPEGPFISLTVSGGHTLLSLVREDLSYDVIGKTLDDAAGEAFDKTGKMLGLAYPAGPVIDRLAASGNPHFHAFPKALTSSSQTSRSYRGNFDFSFSGLKTSVLTWLQKHPAEFIQTHLHDIAASIQYAIVSVLTEKAVAAARYFRTDAISVAGGVSANSALRTAMQEACRHHGIRLYIPGTVYSTDNAAMIASLAGLMLSKGAVRKNNYDVAPFASFAAGAIKASLK
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCP_STAAC
Sequence: MHILVTGFAPFDNQNINPSWEAVTQLEDIIGTHTIDKLKLPTSFKKVDNIINKTLASNHYDVVLAIGQAGGRNAITPERVAINIDDARIPDNDDFQPIDQAIHLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTFVCNHTLYHLGYLQDKHYPHLRFGFIHVPYIPEQVIGKPDTPSMPLEKIVAGLTAAIEAISNDEDLHLALGTTE
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_METNO
Sequence: MGNDKTNMIIAIALSLAVLLGWNYFVAAPQVERQRQQQAQTSASPSPKEGGPSAPVPGTLPGASGGNPQAALTREEALARSPRVRIDTEALKGSVALKGGRIDDVALKGYHETVDPKSPEIVLLSPAGSANPYYAEFGWVGQGAGPLPNGDTVWTADGDLLTAKKPLTLTWDNGAGLVFRRTLSVDDKYMFTVEDSVENKGQSAVTLYPYGLVSRWGKPHTQGYYVLHEGLIGVLGDKGLQEYTYDKMAKENPLGSPGTRGLSWPGVTGGFLGITDKYWAAATIPDQKTPYTGSFTERDEGATKVYQTSSLGEARTLAPGAGVQASQHLFAGAKEVSTIDAYRQKLDIKQFDLMIDWGWFYFITKPMFKALDFFYKLFGNFGVSILVVTLILKLFFLPIANRSYVSMAKMKAVQPEMTAIRERYADDKVKQQQAMMELYRKEKINPVAGCWPVVIQIPVFFALYKVLFVTIEMRHAPFFGWIRDLAAPDPTSVLNLFGLLPFAAPDLVHLGVWPIVMGITMFLQMKMNPAPPDPVQAQVFTFMPIIFTFMLGSFPAGLVIYWAWNNLLSILQQYWIMRRNGVKVELWDNLRTTFSRSSPVKAAKG
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_SULIN
Sequence: MVKHSRGYRTRSRSLLRKSPRERGAVPSLSRLMVEYKEGDKVVIKINPSVHSGMPHRRYQGKVGKIIGKRGRAYLVSVTLGDKEKVIIVRPEHLVSFSSSG
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: MATK_PHAAD
Sequence: MEKFEGYSEKHKSRQQYFVYPLLFQEYIYAFAHDYGLNDSEPVEIVSSNNKKFSSLLVKRLITRMYQQNFWINSVNHPNQDRLLDYKIGFYSEFYSQILPEGFAIVVEIPFSLREFSCPKEKEIPKFQNLRSIHSIFPFLEDKFLHLDYLSHVEIPYPIHLEILVQLLQYRIQDVPSLHLLRFFLNYYSNWNSFITSMKSIFLFKKENKRLFRFLYNSYLSEYEFFLLFLRKQSSCLPLASSGTFLERIIFSRKMEHLGIMYPGFFRKTIWFFMDPLMHYVRYQGKAILASKGTHFLNKKWKWYLINLWQYFFSFWIQPRRIHLNQLANSCFDFLGYLSSVPKSTLLVRNQMLENLFLIDTRMKKLDTIVPATALIGYLSKAQFCTGSGHPISKPIWTDLSDWDILDRFGRICRNLFHYHSGSSKKQTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSAFLEEFFTEEELVFSLMFTKTTLFSFRGSHNERIWYFDIIRINDLVKPLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IOVO_COLVI
Sequence: FAAVSVDCSEYPKPACMSEYRPLCGSDNKTYVNKCNFCNAVVESNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC_COXBR
Sequence: MDIKRIILYVIVALLAIALFNAWQRDYPPTPKPTPTVEQPTANGDHPTAYTPPAFTPGAAEKTKKAGTIAFTSKVPEARLITVRTDVLDVEIDTQGGNIVSAKLPKYPVSLEEKQTPVQILSGEPNELYIAQSGLTNGNGQPTTVQFESEKKQYVLENGQNQLIVQLTGRAPDGLLVTKTYTFHRDDYAIHLAYQVKNNTSKPWQGSLYTQITRRQPPTEHHHFYVRSYNGASMGSPQTPYEKLSYESLDKQNIDRTSQSGWIAMQQHYFLSAWVPGNPELTYHYYSHVIPASDEPNVYVVGFVSPQMNVAAGSEAATHATLYVGPEIAKRLKGLAPGLERTIDYGWLWPISMLLFWILSAVHAVVKNWGWSIIITTILIKIVFYWFSAKSFRSMARMREMQPRIQALKERHGDDRQALSRATMELYRKEKINPLGGCLPMLIQVPVFIAFYYVIIESVQLRQAPFIFWIHDLSVKDPYYILPIIMGLSMLAQQWVSPTSPDPTQQKMMWILPVIFTVFFINFPAGLVLYWITNNVVQTLQQWYVNKTYESHKAKLKARRARKRKR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUR9_BOVIN
Sequence: MAPGQLALFSVSDKNGLVEFARNLASVGLNLIASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARDIPEDSADMAKLDFNLIRVVVCNLYPFGKTVASPGVTVEEAVEHIDIGGVTLLRAAAKNHARVTVVCEPEDYAAVASEMQDSDSKDTSLETRRQLALKAFTHTAQYDEAISDYFRKEYSKGVSQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGLPAAASFKHVSPAGAAVGIPLSEDEANVCMVYDLYKTLTPVATAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYENEALKILSKKKNGNYCVLQMDQSYIPDENEVRTLFGLRLSQKRNNSVVNRSLFSNIVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANCWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEGEDLIKWKALFEEVPELLTETEKKEWIDKLNEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH
What is the function of this protein?
Bifunctional enzyme that catalyzes the last two steps of purine biosynthesis.  Acts as a transformylase that incorporates a formyl group to the AMP analog AICAR (5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) to produce the intermediate formyl-AICAR (FAICAR).  Can use both 10-formyldihydrofolate and 10-formyltetrahydrofolate as the formyl donor in this reaction.  Also catalyzes the cyclization of FAICAR to IMP.  Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization.
What are the official names of this protein?
Bifunctional purine biosynthesis protein ATIC, AICAR transformylase/inosine monophosphate cyclohydrolase, ATIC.
What is the protein family that this protein belongs to?
Belongs to the PurH family.