PharMolix/UniProtQA huggingface dataset:
Protein: HBG_EULFU
Sequence: MVHFTAEEKAVITSLWGKVNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSASAIMGNPKVKAHGKKVLTSLGDAIKNMDDLKGTFAHLSELHCDRLHVDPENFKLLGNELVIVLAKYFGKEFTPQVQAAWQKMVAGVAIALAHKYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma, Gamma-globin, Hemoglobin gamma chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DDX54_MOUSE
Sequence: MAAGRRVGPGPPSRPTMAPWKKKRLRKRRTGASQGRDSDSDDGEFEIQAEDDARARKLGPGRALPSFPTSECVSDVEPDTREMVRAQNKKKKKSGGFQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKARSAQTGARALILSPTRELALQTMKFTKELGKFTGLKTALILGGDKMEDQFAALHENPDIIIATPGRLVHVAVEMNLKLQSVEYVVFDEADRLFEMGFAEQLQEIIGRLPGGHQTVLFSATLPKLLVEFARAGLTEPVLIRLDVDSKLNEQLKTSFLLVREDTKAAVLLYLLQNVVRPQDQTVVFVATKHHAEYLTELLMGQGVSCAHIYSALDQTARKINLAKFTHNKCSTLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEVPYLLDLHLFLGRSVTLARPCEEPSVADAVGRDGVLGRVPQSVVDDEDSSLQTAMGASLDLQGLHRVANNAQQQYVRSRPAPSPESIKRAKELDLAELGLHPLFSSCFEEGELQRLRLVDSIKNYRTRTTIFEINASSKDPSSQMMRAKRQRDRKAVASFQQRRQERQEGPADPAPQRELPQEEEEEMVETVEGVFTEVVGQKRPRPGPSQGAKRRRMETRQRDQEFYVPYRPKDFDSERGLSVSGAGGAFEQQVAGAVLDLMGDEAQNMSRGQQQLKWDRKKKRFVGQSGQEDKKKIKTESGRFISSSYKRDLYQKWKQKQKIDDRDSEEEGPSNQRGPGPRRGGKRGRSQGTSQPRASSVPAGRMRSELKTKEQILKQRRQAQKQRFLQRGGLKQLSARNRRRAQELRQGAFGRGAPSRKGKMRKRM
What is the function of this protein?
Has RNA-dependent ATPase activity.  Represses the transcriptional activity of nuclear receptors (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DDX54, DEAD box protein 54.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CLPB_ACICA
Sequence: MXFEXFTNRLQQALSDAQSL
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T22D3_RAT
Sequence: MNTEMYQTPMEVAVYQLHNFSISFFSSLLGGDVVSVKLDNSASGASVVALDNKIEQAMDLVKNHLMYAVREEVEVLKEQIRELVEKNSQLERENTLLKTLASPEQLEKFQSRLSPEEPAPEAPETPEAPGGSAV
What is the function of this protein?
Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11 (By similarity).  In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10 (By similarity).  In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation and thereby NFKB1 DNA-binding activities (By similarity).  In vitro, suppresses AP-1 transcription factor complex DNA-binding activities (By similarity).
What are the official names of this protein?
TSC22 domain family protein 3, Glucocorticoid-induced leucine zipper protein.
What is the protein family that this protein belongs to?
Belongs to the TSC-22/Dip/Bun family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localization depends on differentiation status of myoblasts. In undifferentiated myoblasts, localizes to the cytoplasm, but in differentiating myoblasts is localized to the nucleus (By similarity).
Protein: QUEA_SYNWW
Sequence: MQHDKNEDIYRLSTYYYDLPPELIAQYPAEYRDSSRLLVLDRKSGDLNDRAFKDISLYLKKGDALVLNETRVIPARFFAYKESGARVEILLLKKLGDDWEALVKPARRLKAGSRVFLSPDKPLVIEIVEELDFAGGRRVRFQDSVDEDTLLQEQGHIPLPPYINRPDEELDRERYQTVYACKSGSVAAPTAGLHFTPDLLKEITLQGINIVRIVLHVGMGTFRPVKNEDIRQHNMHLEYYEVAEDAAALLNLTRESGGQIVAVGTTVVRTLESVYNKDCGFLAGKGETNKYIFPGYQFRAIDKLLTNFHLPGSSLLMLVAGFAGTESTLAAYRHAVENRYRFFSYGDAMLVI
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLI_METS3
Sequence: MKYQELVDVYSALENTTKRLEKTQIISNFLLKLDSTTLEQVGLLILGSIFPAWSDKEIGIGNKLVMQAVGEAVGVTPDKVEDAVRDQGDIGLACISLYAKKSQTTFFSQPLTIDFVFKSLRKLSEKSGARSTKRKIDIILEMLSQASASEAKYLTRTILEELRIGVGEGVVRDAIAQAFNIDKSVVERAMMLTNDLGLIAVVAKEKGEGGLKELNLTPGTPVKPMLAQLAPPIPEIINEMGVAICETKYDGIRLQVHRHSDEIKIFTRRLENITHALPEIVDLFNEYLPHEDYIVEGEVIATRDGNPLSFQNILHRVRRKHNIDEAMEQVPLKVFLFDLLYYIVPMIDEPLLKRRKKLEEIVNTTPDEINLSNMVYGTPDTIKEVEDLFELSIAQHHEGIMIKDAGEPYIPGLRGKKMLKYKAEPETLDMVVVGGTYGIGKRGDFVGSYLVSLRDEDNNLKTVAYVATGLDDATLEYLTKKMKEYELSTKGREIVVEPKIVLEVAFSEIVESPEYETGYSLRFPVVKNIRKDKGVDDIDTVERLISMYETQ
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: ECHB_RAT
Sequence: MTTILTSTFRNLSTTSKWALRFSVRPLSCSSQVQSAPAVQTKSKKTLAKPNLKNIVVVEGVRIPFLLSGTSYKDLMPHDLARAALSGLLYRTNIPKDVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISSNQAMTTAVGLIASGQCDVVVAGGVELMSDVPIRHSRNMRKMMLDLNKAKTLAQRLSLLTKFRLNFLSPELPAVAEFSTNETMGHSADRLAAAFAVSRMEQDKYALRSHSLAKKAQDEGHLSDIVPFKVPGKDTVSKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMSEDRALAMGYKPKAYLRDFIYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAQNYMGRKTKVGAPPLEKFNIWGGSLSLGHPFGATGCRLVMAAANRLRKDGGQYALVAACAAGGQGHAMIVEAYPK
What is the function of this protein?
Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway.  The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA.  Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids.  Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity.
What are the official names of this protein?
Trifunctional enzyme subunit beta, mitochondrial, TP-beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane. Endoplasmic reticulum. Note=Protein stability and association with membranes require HADHA.
Protein: NEUM_CARAU
Sequence: MLCCIRRTKPVEKNEEADQEIKQDGTKPEENAHKAATKIQASFRGHITRKKMKDEDKDGENDTAPDESAETEEKEERVSPSEEKPVEVSTETAEESKPAEQPNSPAAEAPPTAATDSAPSDTPTKEEAQEQLQDAEEPKETENTAAADDITTQKEEEKEEEEEEEEEEEEAKRADVPDDTPAATESQETDQTDKKEALDDSKPAEEAGKDQNV
What is the function of this protein?
This protein is associated with nerve growth.  It is a major component of the motile 'growth cones' that form the tips of elongating axons.  Plays a role in axonal and dendritic filopodia induction (By similarity).
What are the official names of this protein?
Neuromodulin, Axonal membrane protein GAP-43, Growth-associated protein 43.
What is the protein family that this protein belongs to?
Belongs to the neuromodulin family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, growth cone membrane; Peripheral membrane protein; Cytoplasmic side. Synapse. Cell projection, filopodium membrane; Peripheral membrane protein.
Protein: ATPF_DICNV
Sequence: MNINVTLIGQMGTFLVFWWFVNKVIWPMFANIATERQRKIADGLNMADKAKFAVQEAEHQSQEILSKAKMQAAEIVSRANKEASEMIAQAKEQAQRSSEAEVLQAHVQIEQEKRQVRDELRAQLSHLVIAGAEKVLGREVNDRDHERLLHELTEKF
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DESR_MEGGA
Sequence: MANEGDVYKCELCGQVVKVLEEGGGTLVCCGEDMVKQ
What is the function of this protein?
Nonheme iron protein possibly involved in electron transport.
What are the official names of this protein?
Desulforedoxin, DX.
What is the protein family that this protein belongs to?
To the N-terminal section of desulfoferrodoxin.
Protein: IF2_HAEI8
Sequence: MTEDVKADAPKKLSIQRRTKTTVSSTTTGGKSKEVQVEVRKKRTVKTDIAQQEEAKLKAQQEAEAKKIAEQKAAEEKARLEAEKAATKKEADEKSKAEKAKAETAKPAKSAVDSKAKFVDPEKEKRKAEEAELRRKAEEVARQKAEEQARRAAEEAKRYAEADDSDNESSSEDYSDYNLSSRYALEAEDEEDRRNENRGRGKNKVAKAKKGGRDDENSKNSKNERESNRKNQKDAKFGKGKNGKKGTALQQAFTKPVQVVKADVVIGETITVAELANKMSVKATEIIKVMMKMGEMVTINQVIDQETAQLVAEELGHKVILRNENELEEAVLGDRDVNAEKVTRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVEMDDGKMITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAAGAPLVVAVNKIDKPEANPDRVEQELLQHDVISEKFGGDVQFVPVSAKKGTGVDDLLDAILLQSEVLELTAVKDGMASGVVIESYLDKGRGPVATILVQSGTLRKGDIVLCGFEYGRARAMRDENGKEVDEAGPSIPVELLGLSGVPAAGDEATVVRDEKKAREVALYRQGKFREVKLARQQKAKLENMFSNMSEGDVAELNVIVKADVQGSVEAIVQALNELSTNEVKVKVVGSGVGGITETDATLATASNAIIVGFNVRADATARRVIEAENIDLRYYSIIYELLNEIKAAMSGMLEPEFKQEIIGLAEVRDVFRHPKFGAIAGCMVTEGVVKRNNPIRVLRDNVVIFEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVKVGDQIEVFEVVEVKRSI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_ECOUT
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CHEB2_CERS4
Sequence: MKVGNTLMAARAREGRTRVLIVDDSAMVRQALALGLSTDPRLEVVGTASGAEAARAQMAALKPDVVTLDLEMPQMDGLTFLRSYMESAPVPTVVISSLTRTSGETAMRAMEAGAVDIISKPSLGAGQGLPAIMRDVCARVWAAARARLAPPDGAAPAPVATGASEDWIHALGASTGGVQALSRILPFFPAQSPGLLVVQHMPEGFTAAFARRLDALCRMRVREAADGDLVLPGLVLIAPGGLRHMEIERAGGVCRVRLVAGAPVSYSRPSVDRMFLSLAAAAGPRVSAALLTGMGRDGAAGLLAIRRAGGRTFAQDEGSSAVFGMPLAARDLRAAEEILTLDDIPARMMLAAAADTRAPSLASND
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACB_RHORT
Sequence: MADTPPPLIELIDLERVFDSSEVPVRALDRVSLTIHEGEFVAIIGQSGSGKSTLMSILGCLDRPTGGLYRLGGIDVASLDPVALAGLRRDTFGFVFQRYNLLAGASAAENVEMPAVYAGQPRHQRLERAHALLDRLGMGARSGHFPNQLSGGQQQRVSIARALMNDPRVILADEPTGALDSASGRDVLALLEALHTEGRTVILITHDRDVAARAERVIALQDGRVVEDSGRPAPVGSDRPLGRPPGGAAYLGMAASFGEALKMAGRSLRANIFRTALTLLGVVIGVAAVVTMMAIGEGSKQDVLTRIQSMGTNLLLVRPGAPGIRPSGTDVSLTPTDAEAVAQLAGMAAVAPERMASGITVRREGIDYRTTINGTWPAYAAAKDWPMAWGSFFDATDLQASAPVAVLGQTVAKNLFPGEEDPVGSYFLVRNVPFLVIGVLEAKGATPFGQDQDDIVLIPLTTAFARVSGGRYLSSLTARVEDATTIDESQAAIESLLQARHGKVDFQVRNTQSLLEMVEKTQNSLTLLLGAVALISLLVGGIGVMNIMLVSVTERTREIGIRLATGARASDILLQFNTEAVAVCGVGGLAGVGLGLGAALAVAEFGLPVRFTPGPPIVAFCCAFLTGLLFGYLPARKAARLDPVVALSAE
What is the function of this protein?
Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLD_BURM1
Sequence: MTALLIDGNALSKTLRAQAAERAAALTARGHRPGLAVILVGDNPASEVYVRNKIKACEDNGFFSQKDTYPATLSEADLLARIDELNRDPKIHGILVQLPLPAHIDSHKVIEAIAPEKDVDGFHVANAGALMTGKPLFRPCTPYGVMKMFAAHGIALQGANAVVIGRSNIVGKPMAMLLLEAGATVTICHSKTRDLAAHTRQADIIVAAVGKRNILTADMVKPGATVIDVGMNRDDAGKLCGDVDFAGVKEVAGYITPVPGGVGPMTITMLLINTLESAERAAAAA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: VSR_TRVPP
Sequence: MTCVLKGCVNEVTVLGHETCSIGHANKLRKQVADMVGVTRRCAENNCGWFVCVVINDFTFDVYNCCGRSHLEKCRKRVETRNREIWKQIRRNQAENMSATAKKSHNSKTSKKKFKEDREFGTPKRFLRDDVPFGIDRLFAF
What is the function of this protein?
Weak suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that performs sequence-specific inhibition of viral mRNAs expression.  This could be used by the virus to infect efficiently the host the meristem cells.
What are the official names of this protein?
Suppressor of RNA silencing, 16kD cysteine rich protein, P16.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: SYE2_RHORT
Sequence: MTVVTRFAPSPTGFLHIGGARTALFNWLFARHHGGRFLLRIEDTDRVRSTPEAVAAIFDGLEWLGLDWDEEPTFQFARAARHAEAAHELVAKGLAYRCYCTPDELTAMREEQKAKGLPPRYNGLWRDRDPSEAPAGVAPVIRLKAPQDGETTITDSVQGAVTVANNQLDDMILLRSDGTPTYMLSVVVDDHDMGVTHVIRGDDHLTNAFRQTQLYWALGWETPVFAHIPLIHGADGAKLSKRHGALGAEAYRDMGFLPEALRNYLVRLGWAHGDDEVFTTEQAVEWFSLESIGRSPSRFDMQKLTALNGSYMRETDDDRLTALLVPRLESTLGLDIPAAGHALLRAGMAGLKERAKTLVELADLAAFYVRPRPLAIDAKAEKALDDEGRTILAALIDKLDDFSPWTRDSLENLARVMSEERGVKLGKVAQPIRAALTGSTVSPPIFEVMEILGPDETLGRLRDAQSHS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_CYTH3
Sequence: MSTIADSKNHGHQKLTAAGLLISLGIIYGDIGTSPLYVMKAIAGGNVISENLILGGLSCVFWTITLQTTIKYVIITLRADNKGEGGIFSLFALIRRRNPNLVWPAMIGGAAMLADGIITPPISVSSAVEGLLIFNKDIPTIPIVLAIIVMLFMIQRFGTNIVGKFFGPIMFIWFAMLATLGLSQLMGNFYVLKAINPMYAFNLLTQYTTVDDKSGFWLLGAVFLCTTGAEALYSDLGHCGRPNIRISWIFVKLALLINYFGQGAWILQNKGYVIKGNPFFGIMPEWFIVYGIIIATMAAIIASQAMISGSYTLISEALRLNLWPKVRVKYPSVKKGQLFIPSINLLLLAGCIFVVLWFGESSAMEGAYGLAINITFLMTTILLAYYLLIIKRISFIWVGLLILMYLIIEVSFLVANLEKFFHGGYFTLISSGILAFIMIIWYTAHRIKRRLTEYVKIQDYFPLIKELSEDTSIPKYSTHLIYLTGADNYTQIESKVIYSIFQKQPKRADIYWFLHIDVVDEPYTMEYKVRTMLADDVIRIDFKLGFRVEHRINLFFRKVVEDMVNNKEVDFTSRYTSLNKRNVIGDFRFVVLEKHLSNDNDLSVMEQFAMDWYFFLKHISISESSAFGLDTSSVTVEKVPMVISPMEAFQLKRVY
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNFH_PSEF5
Sequence: MAEPMISIEVAYAAVDRQALIRVQVPQGSTLRAALQASAIGQQFPELDLAACPVGIFGKQVSDPEQHVIQAGDRIEVYRPLLADPKEVRRLRAAKAAEARKRES
What are the official names of this protein?
Protein RnfH.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: JNM1_YEAST
Sequence: MNVIDLSDPAINVDYDSLIGIDNEESQEIFENEVKEDGQQEEQEEASSRKDGLIVEPGRDVESLRRAIRDQLLFKIHRQNQSDCADARKLSNDEEDESRQQKLERIREELEELKIENLTSEMQTEIKELCEIQSKLATESSSRLTNLRKKLLETYEGQDTVILPNIILDTSNIKRLQKLDQKISLMERFVGIPEALEAEEDRKSVHSKVNELYRSIQLLQGDDKAEGKLQKFRDRLVELNEEFENSLLGKKIQQDLRLKDDTVSKLVMPENKVKEINSMYSMFKQYQDSLPLLAERMKSLNKMNNRVIEVYETTKGLDSQITSIQEQGKVWLKALNELDKKFDEQEVKIRENMEQIRRKIDTLEDEALQRNSK
What is the function of this protein?
Component of the dynactin complex which assists cytoplasmic dynein by increasing its processivity and by regulation of its cargo binding (By similarity).  The dynactin complex is required for the spindle translocation late in anaphase and is involved in a cell wall synthesis checkpoint.  JNM1 is associated with the rod and links it to the projecting sidearm.  Required for proper nuclear migration during the mitotic cell cycle and for astral microtubule development.
What are the official names of this protein?
Nuclear migration protein JNM1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: OJP1_SEPOF
Sequence: DQVKIVL
What is the function of this protein?
Has myotropic activity targeting the genital tract.
What are the official names of this protein?
Ovarian jelly-peptide 1, OJP1.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_ENCCU
Sequence: MSKQAEEEQLAFLDSGRIIGIINQLKESEDPEKIVTIQIQVNLKGFDPRKDNKVSKDMVLPYRVRSLDKTIVIADEAHVKVCIDANLPYVPIDEISGDDKKDIRESVLKKNKFFILCPGYNKIYQLKNILRCGKTPHILRNGDDINAVFETGKKSCKLRIQDDFSVTSFTVGHTGMDSEHIYENIKVGMGLLVSYLKNGSQNLKGVMIKTDQSPPVTLY
What are the official names of this protein?
60S ribosomal protein L1, L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_BUCA5
Sequence: MEIVSMREMLKAGVHFGHQTRYWNPKMKPFIFGIRNRVHIINLEKTLPMFHFALSELKKIALKKGRILFVGTKKAASKGIKEVAINCEQFYVNHRWLGGMLTNWKTVRQSIKRLKDLEIESKDGTFSKLTKKEALIRSRELFKLENSLGGIKNMGGLPDCLFVIDAAHENIAITEANNLGIPVFSIVDTNSNPDGVDYIIPGNDDAIRSVNLYLKSIMLTISKINNQNSLDKVFIDTKNSTNIE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: ACCA_CAMJJ
Sequence: MASYLDFEKNIQQIDEDIINAQIKGDTEAVSILKKNLEKEISKTYKNLSDFQRLQLARHPDRPYALDYIELILNDAHEIHGDRAFRDDPAIVCFMGYLGEKKIIVIGEQKGRGTKDKIARNFGMPHPEGYRKALRVARLAEKFQIPILFLIDTPGAYPGIGAEERGQSEAIARNLYELSDLKIPTIAIVIGEGGSGGALAIGVADRLAMMKNSVFSVISPEGCAAILWNDPAKSEAATKVMKVTADDLKSQGLIDDVIDEPTNGAHRNKEAAAVAIADYVKKSLNELENIDVRELSANRMQKILKLGAYQEA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_TRIV2
Sequence: MQLTPQEKDKLLIFTAALVAERRKNRGLKLNYPEAVAYISAAILEGARDGNTVAELMSYGTTLLTRDDVMEGIAEMVHEVQVEATFPDGTKLVTVHNPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_STRM5
Sequence: MSRLQFQLQTRDGRARRGRLTFPRGTVETPAFMPVGTYGSVKGILPDQVRALGAEIILGNTFHLYLRPGLDIIADHGGLHGFCRWDGPILTDSGGFQVFSLAHRRKITEQGVTFASPTDGARVFLGPEESMKIQKVLDSDVVMIFDECTPYPATEDVARRSMELSLRWAQRSRNAHDELGNDAALFGIVQGGVHTDLRSRSADALQAIGFDGYAIGGLAVGEPEDERNAMLDHLDPELPADRPRYLMGVGRPEDLVEGVARGVDMFDCVMPTRNARNGHYFTSFGTVRIRNSQYARDMDPIEPGCGCVACTGGYTRSYLRHLDRCNEMLAPMLGTLHNLFYYEKLMADIRAAIEAGTFLAFRESFYAARGAVAPPL
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PON3_HUMAN
Sequence: MGKLVALVLLGVGLSLVGEMFLAFRERVNASREVEPVEPENCHLIEELESGSEDIDILPSGLAFISSGLKYPGMPNFAPDEPGKIFLMDLNEQNPRAQALEISGGFDKELFNPHGISIFIDKDNTVYLYVVNHPHMKSTVEIFKFEEQQRSLVYLKTIKHELLKSVNDIVVLGPEQFYATRDHYFTNSLLSFFEMILDLRWTYVLFYSPREVKVVAKGFCSANGITVSADQKYVYVADVAAKNIHIMEKHDNWDLTQLKVIQLGTLVDNLTVDPATGDILAGCHPNPMKLLNYNPEDPPGSEVLRIQNVLSEKPRVSTVYANNGSVLQGTSVASVYHGKILIGTVFHKTLYCEL
What is the function of this protein?
Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters.  Rapidly hydrolyzes lactones such as statin prodrugs (e. g.  lovastatin).  Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
What are the official names of this protein?
Serum paraoxonase/lactonase 3.
What is the protein family that this protein belongs to?
Belongs to the paraoxonase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.