PharMolix/UniProtQA huggingface dataset:
Protein: PUR7_ACIF5
Sequence: MNERIALYEGKAKIVYASESPDELVLHFKDDTSAFDGEKVEQLAHKGEINNAFNAFIMEYLQGEGVPTHFIRRLNARESLVRRLEMIPVECVVRNRAAGSLSKRLGIEEGRVLEPPTLEFFLKNDALHDPMINTSHIRTFGWATAEEVEAMRRWTMRVNMLLSALFAKANLILVDFKLEFGRFDGELYLGDEFSPDGCRLWDALSLEKMDKDRFRRGLGGVVEAYAEVARRLGVPLPAAS
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RS5_METEP
Sequence: MAREREGRRRDDREERDSEFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRGLIRVSLREGRTLHHDVNGRHGAGKVILRAAPQGTGIIAGGPMRAVFETLGMQDVVAKSLGSSNPYNLVRATFDALKNEDSPRSVAARRGLKVSALQARRRDADPADTSEAAVA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: PHT4_PSEPU
Sequence: MMASHAESTARLRLGVVGLGRAFTLMLPTFLADRRVQLVGACDPREQARRQFERDFDAPAYETIEDLAADSNVDALYIASPHQFHAEHTRIAAANRKHVLVEKPMALSLDECDRMIADCAEAGVKLIVGHCHSFDTPYLRTRELIGSGEFGAVKMIQALNYTDYLQRPRRPEELSTAEGGGAVFSQAAHQVDVVRLLAGSRATRVRAAVGNWDPARPTEGAYTATLWFENGAFASITYNGYGHFDSDEWMDWVGEMGKPKNPEAYGGARRLLQQVQTADEEARLKAEGTYGGTRYVSPSPTDDATAFQHFGPIIVSCEGGDLRPMADAVMIYRPHSRDRMMLERPTVPRSEVIDELYLAQFYGVTPLHDGEWARDTLEICLAMLRSSEEQRDITLGVNVEDTQWRENPSS
What is the function of this protein?
Transforms 4,5-dihydro-4,5-dihydroxyphthalate to 4,5-dihydroxyphthalate.
What are the official names of this protein?
Putative 4,5-dihydroxyphthalate dehydrogenase, DHP dehydrogenase.
Protein: NRDR_SYNP6
Sequence: MQCPACRHTDSRVLESRSSESGRSVRRRRECLSCGHRFTTYERVEFVPISVIKRNGDRESFDRSKLLRGIVRACEKTGVSAQQMDLLVDEIEGTLQQRSSRDVQSSEIGEMVLQQIGRLSEVAYIRFASVYRQFRGVRDFVETLDRLQDLSRDEVGDVPAAVTSLTSA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: YAG5_STALU
Sequence: ILYNKDTDVVILPEMWNNGYALEQLEEKADFDLERSTDFIKNLALQYQVDIIAGSVSNKHHDHIFNTAFAIDKTGKVINQYDKMHLVPMLDEPAFLTAGKNVPETFKLSNGVKVTQMICYDLRFPELLRYPARSGATIAFYVAQWPSARLNHWQVLLKARAIENNMYVIGCNGCGYDGKTQYAGHSVAINPNGEIIQELSTTEKELTVTIDIDAVEQQRKAIPVFDSLVPHLYK
What are the official names of this protein?
Hydrolase in agr operon, ORF 5.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
Protein: GALNS_CANLF
Sequence: MAPVAAATGWRLLLVLSAAGLGAAGAPQPPNILLLLMDDMGWGDLGIYGEPSRETPNLDRMAAEGMLFPSFYSANPLCSPSRAALLTGRLPIRNGFYTTNRHARNAYTPQEIVGGIPDQEHVLPELLKEAGYVSKIVGKWHLGHRPQFHPLKHGFDEWFGSPNCHFGPYDNRARPNIPVYRDWEMVGRYYEEFPINLKTGEANLTQVYLQEALDFIKRQQAAQRPFFLYWAIDATHAPVYASRPFLGTSQRGRYGDAVREIDNSVGKILSLLQDLRISENTFVFFTSDNGAALISAPNQGGSNGPFLCGKQTTFEGGMREPAIAWWPGRIPAGRVSHQLGSIMDLFTTSLSLAGLAPPSDRVIDGLDLLPAMLGGQLTDRPIFYYRGDTLMAVTLGQYKAHFWTWTNSWEEFRQGIDFCPGQNVSGVTTHTQEEHTKLPLIFHLGRDPGERFPLSFASTEYLDVLQRVTPVVQQHQKTLVPGQPQLNVCDRAVMNWAPPGCEKLGKCLTPPESTPKKCSWPH
What are the official names of this protein?
N-acetylgalactosamine-6-sulfatase, Chondroitinsulfatase, Chondroitinase, Galactose-6-sulfate sulfatase, N-acetylgalactosamine-6-sulfate sulfatase, GalNAc6S sulfatase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: COQ8_YEAST
Sequence: MVTNMVKLRNLRRLYCSSRLLRTIQNGRISSVSSISLSKKYTTKSAKEGEENVERKHEEEKKDTLKSSSVPTSRISRLFHYGSLAAGVGMNAAAKGISEVAKGNSPTWKSLILSDSNIDRITNKFSKMRGVALKIGQLLSFQDEKVLPKELYEILSRVQNSANHMPQRQLEKVMAKELGANWKTKFSKFDKIPMAAASIGQVHAAELPSGQRVVVKIQYPGVKESIDSDLNSLLMLLTASSLLPKGLFLDKTIANARTELKWECDYNREARALQKFEALLKDDPAFEVPHVFPEYTTDNIITMTRMEGTEIMKLPKASQETKNFISENIMRLCLEEIATFKYMQTDPNWANFLYNGRTKKIELLDFGASRPFAEDFILKYRKLLTYATLRDRKGAYEMSVQLGYLTGLESQSMKDAHVDSVLTLGEPFRGDVDKSFDFKDQTVSDRIRGNIGLMLNERLCPPPEETYSLHRKFSGIFLLCARMGASVHCAKLFKEIFAYKV
What is the function of this protein?
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294).  Affects the molecular organization and function of COQ3, possibly through kinase activity towards COQ3, COQ5 and/or COQ7 (PubMed:11279158, PubMed:15063807, PubMed:1648478, PubMed:18801050, PubMed:19002377, PubMed:21296186, PubMed:9210471, PubMed:9266513, PubMed:25498144).  Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294).  Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity).
What are the official names of this protein?
Atypical kinase COQ8, mitochondrial, Activity of bc1 complex protein 1, Coenzyme Q protein 8, Ubiquinone biosynthesis protein COQ8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y1613_METNO
Sequence: MADMPSVEPTRIDPKLLELLVCPLTKGRLEYDSARQELISRSAKLAYPIRDGIPIMLPEEARPLAD
What are the official names of this protein?
UPF0434 protein Mnod_1613.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PANE_PYRHO
Sequence: MKIYILGAGAIGSLVGGLLANVGEDVTLIGRGRHIEAINKRGLMIEGLTNLKINTKATTSIPGAKPDLIILTTKSYSTDDALNSAKDIVRDTWVLSLQNGIGNEEKIMELGGRPIGGITTNGAVLKEPGVVEWRGRGITLIGLYPKGRNEFVEEVKETFNRAGLETEVTENIIGWKWAKTIVNSAINPIGAILEVKNGAIKDNDYLLSIAVEVVKEGCKIALQNGIKFDISPMELLIQTLEQTRENYNSMLQDIWRGKRTEIDFINGKIIEYAKLVNLEAPLNFLLWALVKAKESLGGGSK
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPD_YERPA
Sequence: MSDLTSTILFEHPLNEKMRTWLRMEFLLQQLESHRSLDNIANALTFFRTASDLIDVLERGEVRTDLLKELERQQQKLQQWADIPGVDVSLVDSLRNQLKSRAAVLMSAPRIGQSLKEDRLISVVRQRLSIPGGCCSFDLPTLHVWLHQPSEQRDQHINKLLASLAPLHQSLTIILDLIRQSCPLRSQISLNGFFQDNAGGADLLRLRLPLDPQLYPQISGHKTRYAIRFLALDSENGTVPARLSFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: PGA54_CANAL
Sequence: MRANYLLLLAATAVQAAPFIKRYENTTAPASQLSTSLADGSTTILGSSSSSVEEDETITSTIVQYVTVTSSDTTYVSATNTLTTTLTTKPTPVITTEAEDDEEDNETITSTILQYVTVTSSDTTYVSATNTLTTTLTTKAAEATESEEEENETITSTILQYVTVTSSDTTYVSATNTITSVLTTKAAVSTNDVSENAKAATTEDDGETTTSTITSIVTITDANGNTEVLTEVAAETSGAEDASYCVPTTVTVTVTAEQTSEVVSTIVHTTQVPLTAEFTLDDTTTTLTSWVDLTSTDLVTITSTSSVYDSYSTGASQSHPISSYSNYTISDYAPPISSYYSL
What are the official names of this protein?
Predicted GPI-anchored protein 54.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: SYC_MYCBO
Sequence: MTDRARLRLHDTAAGVVRDFVPLRPGHVSIYLCGATVQGLPHIGHVRSGVAFDILRRWLLARGYDVAFIRNVTDIEDKILAKAAAAGRPWWEWAATHERAFTAAYDALDVLPPSAEPRATGHITQMIEMIERLIQAGHAYTGGGDVYFDVLSYPEYGQLSGHKIDDVHQGEGVAAGKRDQRDFTLWKGEKPGEPSWPTPWGRGRPGWHLECSAMARSYLGPEFDIHCGGMDLVFPHHENEIAQSRAAGDGFARYWLHNGWVTMGGEKMSKSLGNVLSMPAMLQRVRPAELRYYLGSAHYRSMLEFSETAMQDAVKAYVGLEDFLHRVRTRVGAVCPGDPTPRFAEALDDDLSVPIALAEIHHVRAEGNRALDAGDHDGALRSASAIRAMMGILGCDPLDQRWESRDETSAALAAVDVLVQAELQNREKAREQRNWALADEIRGRLKRAGIEVTDTADGPQWSLLGGDTK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_GLARU
Sequence: MAPTIRKSHPLLKIINVSFIDLPTPTNISSWWNFGSLLPVCLIAQIATGLFLAMHYTADTSLAFSSVAHICRDVNNGWLLRNLHANGASFFFICIYFHIGRGLYYGSYLYKETWNIGVILLLLVMATAFVGYVLPWGQMSFWGATVITNLLSAAPYIGSDLVQWIWGGFSVDNATLTRFFTFDFILLFIIAATSLIHLLFLHQTGSSNPTGLNSNLDKVSFHPYFSFKDLLGFIILLGALAILSTFAPNLLGDPDNFTPATPLSTPPHIKPEWYLLFAYAILRSILNKLGGVLALLLSIMVLFLMPITHTSKLRSLMFRPTAKAFFWALIANTIILTWIGGQPVEDPFISIGQIASGLYFLIFVLIIPTLGLLENKLLKI
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MNMA_KLEP7
Sequence: MSESQKKVIVGMSGGVDSSVSAYLLLQQGYKVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSQLLRGLDGNKDQSYFLYTLSHEQIAQSLFPVGELEKPQVRKIAEELDLITAKKKDSTGICFIGERKFRDFLGRYLPAQPGKILTVDGEEIGTHQGLMYHTLGQRKGLGIGGTKEGSEDPWYVVDKDVENNILIVAQGHDHPRLMSVGLIAQQLHWVNREPLQGTLRCTVKTRYRQTDIPCTVTALDEDRIEVRFDEPVAAVTPGQSAVFYLGEVCLGGGIIEQRLPLQS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTF_SHIF2
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: SP13B_XENLA
Sequence: MSSQQFPRQAVSMPPPQVSNSGASVGQNVQGDEVAREIDVQSRDPLGASTVLPSRDDKQEPVVVRPYPQVQMLTSHHPLQPAPSLTMTAQPAHLTSAVPLSFSENILKTPKSTMPSRPIAPAPPSALSAVPKVSGQGTVTMESGLPQTSAIPVATISGQQGHPNSLHHIMAATNVQMSIIRSGAPGPPLHIGASHLPRGAAAAAVMSSSKVTTMLRPASAQIPSAAASQSATQHIIHPPIQSRPPVTTTSVSPAVVATVSATRAQSPVITTTPAHAAEPVLRPTLAFQQHPPPAAISIQRSAQARDAATTRITLPTHPALGGQKPQLHAMTQKTLFGTGNPVAAATVAPILATNTLPSVTTSGSAPHTQVSTSTIVTMTMPTHSSHATAGTASNIPVAKVVPQQITHTSPRIQSEYGTERGNLIPIPGHRASPNPMTMEARSENRQPVPVQLQYFLPTYPPSAYPLTAHTYTPITSSVSTIRQYPVSAQAPNSAITAQSVASTVHLNPMQLINMDTSHTRHIQGIQPAPVSAQGIQPSPFSAQGIQATPISTQGIHPTPINTQAIHPATSITNQGVQTSSVSSQQASSEPKSSVVLAEGATIIANPINSSFSATPAGTTVMQSHSQSPGIGSSPAQGSSPRPSILRKKPATEGLSVRKSLIPPHPGDAVSPRHDSALRSTSASPRPAGAKPKADLHVSVAPGVTGDPGAADQPSAAASLPSSHHPTAAVPSPPSQPVSGPMPSSIHITPATIPALSAPPPLLSNAPSGAVMPEDKMKEEAEPMDILRPVSAVPPLPPNSISSPLTVLANNISGPAGELPPGASPRKKPRKQQHVISTEEGDMMETNSTDEERCHAVKPFTSRPEKRKSPPKEYIDEEGVRYVPVRPRPPITLLRHYRNPWKAAYHHFQRYTDVRVKEEKKLTLQDVANQKGITCRVQGWKTHLCAAQLLQLIKLEQDVFERLTVLQEGLVPKKKTATDDDLHRINELIQGNMQRCKLVMDQITESRDCMLKVLDHKDRVLKLLNKSGASRRLSKVKPKDKM
What is the function of this protein?
Acts as a transcriptional repressor.
What are the official names of this protein?
Histone deacetylase complex subunit SAP130-B, 130 kDa Sin3-associated polypeptide B, Sin3-associated polypeptide p130 B.
What is the protein family that this protein belongs to?
Belongs to the SAP130 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SSRP_SHEWM
Sequence: MAKKNAKKSKNSSASIARNKRATFDYKFEEKMEAGLSLMGWEVKSIRMGKVNLSESYVFMREGEAFLFGCTIAPLNTASTHVVCDPMRSRKLLLKRKELDKLQGLVDRKGYSIVPISMYWQKGAWVKIEIGLGKGKKEHDKRDDTKDREWQIEKARTMKKAVQQ
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: 3001L_ASFK5
Sequence: MASLATCCLKNIVNQHAHLENTVLLYHLGLRWNCKTLYQCTQCNGVNYTNLHSDQCKNKDLFLMKVIVKKNLAVARTLLSWGASPEYARLFCRNTEEEQALNLQHVAEVPSHKILERLTMSYKENDEQLLITFYLLNLSTNVSANLREQVRFNIVSYIICDLAIHQTFKIFYAKNYSLSTLYCIFLAIYYKLYTALRKMVKIYPGIKPFAYLIGFMFDDETVTETYSSTDDEILECKNKIIAIKGYYGNIHCRSDIAHMYAFSQNNFW
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 300-1L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 300 family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: MENC_SALDC
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLRDGEREGWGEISPLPGFSQETWEEAQTALLTWVNDWLQGSEGLPEMPSVAFGASCALAELTGVLPEAADYRAAPLCTGDPDDLVLRLADMPGEKIAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKAQQFAKYVNPDYRARIAFLEEPCKTRDDSRAFARETGIAIAWDESLREADFTFEAEEGVKAVVIKPTLTGSLDKVREQVAAAHALGLTVVISSSIESSLGLTQLARIAAWLTPGTLPGLDTLHLMQAQQVRPWPGSALPCLKRDELERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: Y5534_DICDI
Sequence: MMSTSYYQHIGYQDISVSKYKYICDPKDKVILNSVSWEEYKVKNNINRINDYINPHYPIHKLLE
What are the official names of this protein?
Putative uncharacterized protein DDB_G0283461.
Protein: GAL1_ROSS1
Sequence: MLDTGELRERFQQHYGIHPHVIVRAPGRVNLIGEHTDYNDGFVFPVAIDRATCVAARPRTDRIVRVMAADLHDEDLFSIDQIERSNRAWHNYIRGVVLALRTAGHTLSGADMLIASDVPRGAGLSSSAALEVAVAYTFQVLNRLNILGEELALLAQGAENTFVGVQCGIMDQLIAVFGRADHALLIDCRDLTYRAVPLPPSVAVVVCDSHIARTLAASAYNQRRQECDAAVRALQQWYPGIRALRDVSEDQLAAHQHELPEPLRARARHVVSENRRALQGAAALEAGDIATFGRLMNESHASLRDDYQVSLPDIDFLVTTAQSLAGCYGSRLTGAGFGGCTVSLVERSSVETFRHDLAQAYHDATGRTATIYVCRASDGVGRVMDNARPQE
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMD1_CAEEL
Sequence: MPTGKSESSDISEVVGNMEISKVEGLEACIGMSHEVSTTPAAELAAFRARKVALITGISGQDGSYLAELLLSKGYKVHGIIRRSSSFNTARIEHLYSNPITHHGDSSFSLHYGDMTDSSCLIKLISTIEPTEVYHLAAQSHVKVSFDLPEYTAEVDAVGTLRLLDAIHACRLTEKVRFYQASTSELYGKVQEIPQSEKTPFYPRSPYAVAKMYGYWIVVNYREAYNMFACNGILFNHESPRRGETFVTRKITRSVAKISLGQQESIELGNLSALRDWGHAREYVEAMWRILQHDSPDDFVIATGKQFSVREFCNLAFAEIGEVLQWEGEGVEEVGKNKDGVIRVKVSPKYYRPTEVETLLGNAEKAKKTLGWEAKVTVPELVKEMVASDIILMKSNPMA
What is the function of this protein?
Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose (PubMed:16650000).  Involved in susceptibility to pore-forming crystal toxins in conjunction with bre-2, bre-3, bre-4, and bre-5 (PubMed:10924467, PubMed:17135259, PubMed:17482642).  Involved in susceptibility to the nematotoxic C. cinerea galectin Cgl2, likely by contributing to the synthesis of N-glycans to which Cgl2 binds (PubMed:20062796).  Has a role in determining brood size (PubMed:10924467).
What are the official names of this protein?
GDP-mannose 4,6 dehydratase 1, Bacillus thuringiensis toxin-resistant protein 1, Bt toxin-resistant protein 1, GDP-D-mannose dehydratase, GMD.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
Protein: PDXT_HALWD
Sequence: MIQAGVVAVQGDVSEHAAAIRRAGESHSISVEIVEIRQSGVVPDCDVLLIPGGESTAISRLLDREGIDTEIQAHVEAGKPVLATCAGLIIAARDAKDDRVETLDIIDVTVDRNAFGRQIDSFEAPLDVDGLDEPFPAVFIRAPVIDAAGEDATVLAQWEDNPVAVQDGAVVATAFHPELTPDSRIHDLAFFANQNNNVDTAVSTD
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: INH12_ECOLI
Sequence: MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH
What is the function of this protein?
Involved in the transposition of the insertion sequence IS5.
What are the official names of this protein?
Transposase InsH for insertion sequence element IS5-12.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: SH_HRSV1
Sequence: MGNTSITIEFTSKFWPYFTLIHMILTPISLLIIITIMIAILNKLSEHKTFCNKTLELGQMYQINT
What is the function of this protein?
Viroporin that forms a homopentameric ion channel displaying low ion selectivity.  May play a role in virus morphogenesis and pathogenicity at various stages of the viral life cycle.  Accumulates at the membrane of the Golgi apparatus in infected cells and may facilitate virus release by modifying the secretory pathway.  May enhance host membrane permeability and disrupt cellular ion homeostasis, which can be sensed as damage-associated molecular patterns/danger signals, triggering NLRP3 inflammasome activation and inflammatory immune response.  Also inhibits host TNFA-mediated signaling pathway and may delay apoptosis, allowing time for the virus to replicate.
What are the official names of this protein?
Small hydrophobic protein, Small protein 1A.
What is the protein family that this protein belongs to?
Belongs to the orthopneumovirus small hydrophobic protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Host Golgi apparatus membrane; Single-pass type II membrane protein. Host endoplasmic reticulum membrane; Single-pass type II membrane protein. Note=Present in very small amount in the virion. Detected in lipid rafts of host Golgi apparatus membrane.
Protein: ZDH14_ARATH
Sequence: MHRSGTTMAWNVFKFCTALRGLGSIMILLVLGVVGVTYYAVVLTNYGPALSQGGLDSLAALTILILFHFLLAMLLWSYFSVVFTDPGVVPPNWRPSTDEERGESDPLNSLDFVGLQSDSSSSNPRVRFCRKCNQLKPSRCHHCSVCGRCVLKMDHHCVWVVNCVGALNYKYFLLFLFYTFLETTLVTLVLMPHFIAFFSDEEIPGTPGTLATTFLAFVLNLAFALSVMGFLIMHISLVAGNTTTIEAYEKKTTTKWRYDLGKKKNFEQVFGMDKRYWLIPGYTEEDLRRMPELQGLEYPSKPDFDSQ
What is the function of this protein?
Palmitoyl acyltransferase.
What are the official names of this protein?
Probable protein S-acyltransferase 14, Probable palmitoyltransferase At3g60800, Zinc finger DHHC domain-containing protein At3g60800.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.
Protein: OPPB_ECOLI
Sequence: MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHWLPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIRY
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Oligopeptide transport system permease protein OppB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAA_THEP1
Sequence: MVLVVDYGSQYSRLITRRIRENEVYSEVVFPDDKVDLSKVDTVILSGGPRSVYEEDAPKLPEWFQEYKGPVLAICYGMQLIVKELGGEVRRGRGEYGRTLVELSRDPIFEGIPEKVHVWMSHGDEVVRLPEGFHPIAVSETGVIAAATDGKRFWLLQFHPEVHHTEYGDRMISNFLFNVCKLEKNWKIGDLVEEKIRHIKETIGNKKAILALSGGVDSSVAAVLVHRAIGKNLVCVFVDHGLLRKNEREEVERVFKEHFDMNLVVVDARKRFLEKLRGVTDPEKKRKIIGEEFIRVFEEEAKKHDVEFLVQGTIYSDVIESAASGKTTAKIKSHHNVGGLPEKMNLKLVEPLRDLFKDEVRKVGKYLGIPDRIINRHPFPGPGLAVRVLGEVTEEKLEILREADYIFIETLRKHDYYDKVWQAFAVLLPIKSVGVKGDARAYEYVVALRAVNSVEGMTADWSRIPHDILDEAARRITREVKGVGRVVYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NUOA2_PSEAE
Sequence: MPNPAELAAHHWGFAAFLLGVVGLLAFMLGVSSLLGSKAFGRSKNEPFESGIVPTGGARLRLSAKFYLVAMLFVIFDVEALFLFAWSVSVRESGWAGLIEATIFIAILLAGLVYLWRIGALDWAPESRRKRQAKLKQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A 2, NADH dehydrogenase I subunit A 2, NDH-1 subunit A 2, NUO1 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.