PharMolix/UniProtQA huggingface dataset:
Protein: NOS2_CAVPO
Sequence: MACPWNFLWKLKSSRYDLTEEKDINNNVGKASHLYSPEIQDDPKYCSPGKHQNGSSQSLTGTAKKVPESQSKPHKPSPTCSQHMKIKNWGNGMILQDTLHTKAKTNFTCKPKSCLGSVMNPRSMTRGPRDTPIPPDELLPQAIEFVNQYYDSFKEAKIEEYLARVETVTKEIETTGTYQLTGDELIFATKLAWRNAPRCIGRIQWSNLQVFDARSCHTAQEMFEHICRHVRYSTNNGNIRSAITVFPQRTDGKHDFRVWNAQLIRYAGYQMPDGTIQGDPANLEFTQLCIDLGWKPRYGRFDVLPLILQADGRDPELFEIPPDLVLEVPMEHPKYEWFQDLGLKWYALPAVANMLLEVGGLEFPACPFNGWYMGTEIGVRDFCDAQRYNILEEVGRRMGLETHTLASLWKDRAVTEINVAVLHSFQKQNVTIMDHHSAAESFMKHMQNEYRARGGCPADWIWLVPPISGSITPVFHQEMLNYILSPFYYYQVEAWKTHVWQDETRRPKRREIPFRVLAKATLFASLLMRKMMASRVRATILFATETGKSEALAQDLGALFSCAFNPKVLCMDQYQLSSLEEEKLLLVVTSTFGNGDCPGNGETLKKSLFVLKKLTNTFRYAVFGLGSSMYPRFCAFAHDIDIKLSQLGASQLTPVGEGDELSGQEDAFCTWAVQTFQAACAAFDVRGRHHITIPKRYTSSVTWEPYHYRLVQDSQPLDLNKALSRMHATDVFTMRLKSQKNLQSPKSSRTTLLMELSCDDSRSLAYLPGEHLGVFPCNQPALVQGILECVVDNPGPHHTVCLEVLDDSGSYWAKDKRLPPCSLSQALTYFLDITTPPTQLQLQKLARLATEQAERLRLESLSQPSEYNKWKFTNSPTFLEVLEEFPSLRVPAAFLLSQLPILKPRYYSISSSLDHTPAEVHLTVAVVTYRTRDGRGPLHHGVCSTWFSGLKPQDPVPCLVRSVNSFQLPKDPSQPCILIGPGTGIAPFRSFWQQRLHNLKHTGLQGGRMTLLFGCRHPEEDHIYKEEMQEMVQKGVLHEVHTAYSRLPGKPKAYVQDILRQQLAREVLRVLHEEPGHLYVCGNVLMAQDVACTLKQLLAAKLNLNEEQVEDYFFQLKSQKRYHEDIFGAVFPHGVKKDRAERPPGDDKL
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.  In macrophages, NO mediates tumoricidal and bactericidal actions.  Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2.  As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM.  Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8.
What are the official names of this protein?
Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Localizes as discrete foci scattered throughout the cytosol and in the presence of SPSB1 and SPSB4, exhibits a more diffuse cytosolic localization.
Protein: RHAD_SALSV
Sequence: MQNITDSWFVQGMIKATSDAWLKGWDERNGGNLTLRLDETDIAPFAANFHEKPRYIALSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKIDSDGAGYHILWGLTHDAVPTSELPAHFLSHCERIKATHGKDRVIMHCHATNLIALTYVLENNTALITRKLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAEVLVKIYSMGGMKQTITREELVALGKRFGVTPLASAVALY
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHH_IPOPU
Sequence: MTAPATRKDLMIVNMGPHHPSMHGVLRLILTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNGPERLSNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELIYDLFEAATGMRMMHNFFRIGGVAADLPHGWIDKCLDFCNYFLTGVAEYQKLITQNPIFLERVEGIGTIRAEEALNWGLSGPMLRASGIEWDLRKIDQYECYDEFAWEVQWQKEGDSLARYLVRIGEMEESIKMIQQALEGIPGGPYENLEIRRFDRVKHPQWNDFEYRFIAKKTSPIFELSKQELYVRVEAPKGELGIFLIGDQSVFPWRWKIRPPGLINLQILPQVVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: FA5V_OXYMI
Sequence: MGRYSVSPVPKCLLLMFLGWSGLKYYQVNAAQLREYRIAAQLEDWDYNPQPEELSRLSESELTFKKIVYREYELDFKQEKPRDELSGLLGPTLRGEVGDILIIYFKNFATQPVSIHPQSAVYNKWSEGSSYSDGTSDVERLDDAVPPGQSFKYVWNITAEIGPKKADPPCLTYAYYSHVNMVRDFNSGLIGALLICKEGSLNANGAQKFFNREYVLMFSVFDESKNWYRKPSLQYTINGFANGTLPDVQACAYDHISWHLIGMSSSPEIFSVHFNGQTLEQNHYKVSTINLVGGASVTANMSVSRTGKWLISSLVAKHLQAGMYGYLNIKDCGHPNTLTRKLSFRELRRIMNWEYFIAAEEITWDYAPEIPSSVDRRYKAQYLDNFSNFIGKKYKKAVFRQYEDGNFTKPTYAIWPKERGILGPVIKAKVRDTVTIVFKNLASRPYSIYVHGVSVSKDAEGAIYPSDPKENITHGKAVEPGQVYTYKWTVLDTDEPTVKDSECITKLYHSAVDMTRDIASGLIGPLLVCKLKALSVKGVQNKADVEQHAVFAVFDENKSWYLEDNIKKYCSNPSSVKKDDPKFYKSNVMYTLNGYASDRTEVLGFHQSEVVQWHLTSVGTVDEIVPVHLSGHTFLSKGKHQDILNLFPMSGESATVTMDNLGTWLLSSWGSCEMSNGMRLRFLDANYDDEDEGNEEEEEDDGDIFADIFSPPEVVKKKEEVPVNFVPDPESDALAKELGLLDDEDNPEQSRSEQTEDDEEQLMIASVLGLRSFKGSVAEEELKHTALALEEDAHASDPRIDSNSARNSDDIAGRYLRTINRRNKRRYYIAAEEVLWDYSPIGKSQVRSLPAKTTFKKAIFRSYLDDTFQTPSTGGEYEKHLGILGPIIRAEVDDVIEVQFRNLASRPYSLHAHGLLYEKSSEGRSYDDNSPELFKKDDAIMPNGTYTYVWQVPPRSGPTDNTEKCKSWAYYSGVNPEKDIHSGLIGPILICQKGMIDKYNRTIDIREFVLFFMVFDEEKSWYFPKSDKSTCEEKLIGVQSSHHTFPAINGIPYQLQGLMMYKDENVHWHLLNMGGPKDIHVVNFHGQTFTEEGREDNQLGVLPLLPGTFASIKMKPSKIGTWLLETEVGENQERGMQALFTVIDKDCKLPMGLASGIIQDSQISASGHVEYWEPKLARLNNTGMFNAWSIIKKEHEHPWIQIDLQRQVVITGIQTQGTVQLLKHSYTVEYFVTYSKDGQNWITFKGRHSETQMHFEGNSDGTTVKENHIDPPIIARYIRLHPTKFYNTPTFRIELLGCEVEGCSVPLGMESGAIKNSEITASSYKKTWWSSWEPFLARLNLEGGTNAWQPEVNNKDQWLQIDLQHLTKITSIITQGATSMTTAMYVKTFSIHYTDDNSTWKPYLDVRTSMEKVFTGNINSDGHVKHFFKPPILSRFIRIIPKTWNQYIALRIELFGCEVF
What is the function of this protein?
Snake prothrombin activator that attacks the hemostatic system of prey.  This non-catalytic subunit is functionally similar to blood coagulation factor V.  It serves as a critical cofactor for the prothrombinase activity of the catalytic subunit, which is similar to the blood coagulation factor X.  The complex converts prothrombin to thrombin by sequential cleavage at two positions, Arg-320 followed by Arg-271.  Cleavage at Arg-320 produces an active intermediate known as meizothrombin.  Meizothrombin is the 'second' substrate for prothrombinase, and it docks in an altered manner to present the second cleavage site (271).  Cleavage at Arg-271 releases active thrombin from its pro-fragment.  This order of events is reversed if the protease component of prothrombinase is used on its own, suggesting that the 271 site is inherently more accessible to proteolysis.
What are the official names of this protein?
Venom prothrombin activator omicarin-C non-catalytic subunit, vPA, Venom coagulation factor Va-like protein.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFA_ECOSM
Sequence: MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_SHEDO
Sequence: MPRVKRGVTARARHKKVLKLAKGYYGARSRTYRVAVQAVTKAGQYAYRDRRQKKRQFRQLWIARINAAARQNGLSYSRFINGLKKASIEIDRKILADIAVFDKVVFATLVEKAKEALN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ATPA_PELHO
Sequence: MVPIRADEIRNLIRERIEQYNREVKIVNTGTVLQVGDGIARIYGLNEVMAGELVEFEEGTIGIALNLESNNVGVVLMGAGLMIQEGSSVKATGRIVQIPVSEAYLGRVINALAKPIDGRGGISASESRLIESPAPGIISRRSVYEPLQTGLIAIDSMIPIGRGQRELIIGDRQTGKTAVATDTILNQQGKNVICVYVAIGQKASSVAQVVTTFQEKGAMEYTIVVAETAASPATLQYLAPYTGAALAEFFMYRERHTLIIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKSSSSLGEGSMTALPIVETQSGDVSAYIPTNVISITDGQIFLSADLFNSGIRPAINVGISVSRVGSAAQIKAMKQVAGKSKLDLAQFTELEAFAQFATDLDKTTQSQLARGRRLRELLKQSQADPLAVEEQIMTVYTGINGYLDSLEIGQVRKFLEDLRKYLKGNKPKFQEIISSTKTFTEEAEALLKEAIQEQTELFILKEQG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: HMP_PECAS
Sequence: MLDNHTIAIVKSTIPLLAETGPKLTAHFYDRMFTHNPELKDIFNMSNQRNGDQREALFNAICAYATNIENLAALLPAVERIAQKHTSFNIQADQYQIVGNHLLATLDEMFSPGQEVLDAWGKAYGVLANVFIQREDDIYRSTETKTGGWSGVRPFRIVNKQLQSSVITSFTLEPTDGQPIADFQPGQYLAIYIKHDSFANQEIRQYSLTHAPNGKSYRIAVKREAQGTVSGYLHDTAREGDIVHLAAPHGDFFLDIPTDTPVALISGGVGQTPMLGMLHTLKQQDHQAKVLWLHAAENGTAHAFTDEIEQTGQALPHFDHHIWYREPQQTDRPGEDYHHSGLMQLASLKGELTTPDMHYYLCGPVVFMQFVAQQLLAMGIPAEQLHYECFGPHKVV
What is the function of this protein?
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds.  Therefore, plays a central role in the inducible response to nitrosative stress.
What are the official names of this protein?
Flavohemoprotein, Flavohemoglobin, Hemoglobin-like protein, Nitric oxide dioxygenase, NO oxygenase, NOD.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: NUOB1_CHLT3
Sequence: MSGQQGMGDGFLTTTLDAITNWGRANSIWPMPMGLSCCAIEMMAMAGPRYDIARFGAEVFRFSPRQSDLMIVAGTVTYKMATVVKKIWDQMPEPKWCIAMGACSSSGGMFRSYPVVQGIDQFLPVDVYVPGCPPRPDAVIHAVMEIQEKIKRQKDSFQDSFLAEDDAPQVRQPESPKEKEKLTVSE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y097_OSHVF
Sequence: MSTVKIISEEMCVACFDENVKLYIYDCGHKCCCKECFERVERCPMCRHLPVENIKPSTHVPAIPSAPSFELINMEVETREIHPRSSRAKSIAKRMVYGMGPSFLDKLFDCKSGRDSMAWGKMCCICTKKTNDEMIKSKICESYYCRDCRDYLFQENGADQPLPFCPCCFKKYNGFEHVSAH
What are the official names of this protein?
Putative RING finger protein ORF97.
Protein: GLYA_STAS1
Sequence: MSFIQKQDKEIYEVIQNEFNRQNNNIELIASENFVSEAVMEAQGSVLTNKYAEGYPNRRYYGGCEYVDVSETLAIDRAKKLFGAEHVNVQPHSGSQANMAVYLVALEHGDTVLGMNLSHGGHLTHGAPVNFSGQFYNFVEYGVDQENEQIDYDEVLKVAKEHKPKLIVAGASAYSRTIDFKRFKEIADEVGAKLMVDMAHIAGLVAVGLHPNPVEYADFVTTTTHKTLRGPRGGMILCKEEYKKQIDKTIFPGIQSGPLEHVIAAKAVAFGEALQDDFKVYQQQVIQNAKTLANTLTDEGFRVVSGGTDNHLVAVDVKGSVGITGKVAEETLDAIGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDETAFEEVAKIISLVLKDPENEKALAEGKERVNTLTSKHPLYN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D105A_HUMAN
Sequence: MALIRKTFYFLFAMFFILVQLPSGCQAGLDFSQPFPSGEFAVCESCKLGRGKCRKECLENEKPDGNCRLNFLCCRQRI
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 105, Beta-defensin 5, BD-5, DEFB-5, Defensin, beta 105.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: BOP1_DANRE
Sequence: MSKLKNKKRHLEENEEEQLPIFDKDSGEDGHLDDGDEDPADLSDSEESVFSGLEDSGSDDEDDDEDDDEDDDDKDGSEEKSSDAEEDKADDDDGDLKLSAKDDVKPQVDSQNSKEKKKKKRKGKSVLKDGGEEDVASGRDEALKITSQVDEYDHDTSDEEDIRNTVGNIPMEWYKDYPHIGYDLDGKKIFKPIRNKDELDEFLDKMENPDYWRTVQDKMTGADIRLSDEQVDLVHRLQQGKFGDVNFNEYEPAVDFFSNEVMIHPVTNRPQDKRSFIPSLIEKEKVGKLVHAIKMGWIKPRRPKETTPQYYDLWAKEDPNSILGRHKMHVPAPKMKLPGHEESYNPPPEYLLSEEERLAWAAQDPEDRKLSFLPQKFSCLRAVPAFSRFIHERFERCLDLYLCPRQRKMRVNVNPEDLIPKLPKPKDLQPFPTTQSLVYRGHSSLVRSISVSPSGQWLVSGSDDCTVRFWEVSTARCLKTVQVGGAVKGVAWNPNPSICLVAVSYEDSVLLLNPALGDRLLCTATDQLISSYAEPEEVKEQPVQWLVSEGEGHEQGHRLVLKHPKAVRQVTWHAKGDYLACVLPDSSSSVQVLIHQVSKRRTQNPFRKSKGLVQCVSFHPVRPYFFVATQRYVRVYNLIKQELTKKLMANCKWISSMAIHPGGDNVICGSYDCRLAWFDLDLSTKPYKVLRHHKKALRSVSFHSHYPLLASGSDDGSVIVCHGMVYNDLLQNPLIVPVKVLKGHSITHDLGVLDVTFHPTQPWVFSSGADATIRLYT
What is the function of this protein?
Component of the PeBoW complex, which is required for maturation of 28S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein bop1, Block of proliferation 1 protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: PANC_XYLF2
Sequence: MIDTVTDLSRLRGIVADWRRQGLRVALVPTMGNLHAGHFSLVMLARHYADRVVSSVFVNPTQFGPHEDFQRYPRTPEADMRGLEHVGCDVLWLPSVETMYPLGTERTVRLFIPCVSDVLEGTFRPGHFEGVCTVVARLFNQVLPDVAVFGKKDYQQLVVIRQMVVDLAFPIEILGGCIVRESDGLAMSSRNQYLSMQQRPQAAEIHRTLIAMRDAVMSGGVHADVEAEAVRRLEAAGFQVDYAVIRLPDLCEPIDGIVISQGIALVAARLGNTRLIDNLEF
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGCQ_SHISS
Sequence: MGVVRVQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAVTEFEQHRDEHAWQIELNRRRTLSVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHNTSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRLYNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVCASDNA
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity).  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria.  Involved in the regulation of cellulose production (By similarity).
What are the official names of this protein?
Probable diguanylate cyclase DgcQ, DGC, Cellulose synthesis regulatory protein.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPA_XANCP
Sequence: MATTLNPSEISDLIKTRIEAVKLSAESRNEGSVTSVSDGIVRIFGLADVMQGEMIELPNNTFALALNLERDSVGAVVLGDYENLREGDVAKTTGRILEVPVGPELLGRVVNALGEPIDGKGPLGATQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELVIGDRQTGKTALAIDAVINQKGTGIKCVYVAIGQKASTVANIVRKLEENGALAHTVVVAATASESAAMQYISPYAGCTMGEYFMDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTNGAVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDEATRKQLERGQRVTELMKQKQYAPMSIANQALSIYAVNEGYLDEVPVNKLLAFEEGLHAHFANTQGELVSKINTTGGWDNDIEAAFKKGIEEFKTTGSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALDH6_YEAST
Sequence: MTKLHFDTAEPVKITLPNGLTYEQPTGLFINNKFMKAQDGKTYPVEDPSTENTVCEVSSATTEDVEYAIECADRAFHDTEWATQDPRERGRLLSKLADELESQIDLVSSIEALDNGKTLALARGDVTIAINCLRDAAAYADKVNGRTINTGDGYMNFTTLEPIGVCGQIIPWNFPIMMLAWKIAPALAMGNVCILKPAAVTPLNALYFASLCKKVGIPAGVVNIVPGPGRTVGAALTNDPRIRKLAFTGSTEVGKSVAVDSSESNLKKITLELGGKSAHLVFDDANIKKTLPNLVNGIFKNAGQICSSGSRIYVQEGIYDELLAAFKAYLETEIKVGNPFDKANFQGAITNRQQFDTIMNYIDIGKKEGAKILTGGEKVGDKGYFIRPTVFYDVNEDMRIVKEEIFGPVVTVAKFKTLEEGVEMANSSEFGLGSGIETESLSTGLKVAKMLKAGTVWINTYNDFDSRVPFGGVKQSGYGREMGEEVYHAYTEVKAVRIKL
What is the function of this protein?
Cytosolic aldehyde dehydrogenase which utilizes NADP(+) as the preferred coenzyme.  Performs the conversion of acetaldehyde to acetate.
What are the official names of this protein?
Magnesium-activated aldehyde dehydrogenase, cytosolic, Mg(2+)-activated acetaldehyde dehydrogenase, Mg(2+)-ACDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NBS1_ORYSJ
Sequence: MVWALTPVDTVRGAQRCYIFAAGTYKVGRKDCDVIVQTDTSISRVHAEIVVEKMVAWDPQSGAPANPSYVRVVDRSKYGTFFNKVQGTQGSRLHKDEDAMLADGDTVTFGTGNATFRLSFVPIVVFFHGKKSGRISPCLQAVMTSIGAYATRKWSDECTHVLVDESCSLTPELLDAVLAKKQIVLGDWFKVMAEKNIHTEMPSSTQYIPKLTLDGMEIQVVEIKLIESCLAGYTFILGSSEKYKFGDKLHALLESTGAKYLHVDEFCANSQDSGAGENDKDILLVPAKSPLEFSKIRGLFPLSKITDVKLFAAILSGHLEATAIEPPAYIVASSNSTDETIVVDSDVEIDTATSDHTVAASKSEHHIEHISDDKKEVVAISEEDAVNLVEAKTSINLHSDQEKDEIVKPMEEDVKVIEKTATMRGFKVEGEDIPVMTKVPKDETLDSRDETCHVIYTQNLVVKSILQSARAESIETGGINFKRFRKRGAVSGNSFKDLIPYSREPYRESDYERGTVTDFMREEKKRRQMEAIAEDLFNNAKPKKKAAAGSSIHTMLTGRR
What is the function of this protein?
Component of the MRE11-RAD50-NBN complex (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity.  The complex may be involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, and cell cycle checkpoint control.  Functions also in the very early stages of meiosis.
What are the official names of this protein?
Nibrin homolog, Nijmegen breakage syndrome 1 protein, OsNbs1.
What are the subcellular locations of this protein?
Nucleus, PML body.
Protein: Y1194_RHORT
Sequence: MPRPRKTRTVRTDLAVHFYKPQGIPLRDLQSVTLSLDGLEALRLADVEGLEHAAGADSMGISRPTFSRLLTEARTTVATALVEGWAIHIDGGPVAQGPALDGSACPNRRQRRGPCARRGAAGALARQTGDEPPSSPTDNEKDD
What are the official names of this protein?
UPF0251 protein Rru_A1194.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.
Protein: SAHH_BRUO2
Sequence: MTASQDFVVKDISLADWGRKELDIAETEMPGLMAAREEFGKSQPLKGARISGSLHMTIQTAVLIETLKVLGAEVRWASCNIFSTQDHAAAAIAATGTPVFAVKGETLEEYWTYTDQIFQWPDGEPSNMILDDGGDATMYILIGARAEAGEDVLSNPQSEEEEVLFAQIKKRMAATPGFFTKQRAAIKGVTEETTTGVNRLYQLQKKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGVRRGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAASTADIVVTTTGNKDVITIDHMRKMKDMCIVGNIGHFDNEIQVAALRNLKWTNVKPQVDLIEFPDGKRLILLSEGRLLNLGNATGHPSFVMSASFTNQVLGQIELFTRTDAYKNEVYVLPKHLDEKVARLHLDKLGAKLTVLSEEQAAYIGVTPQGPFKSEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_STRA5
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNVIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEALRWGAEVFHALKKILKERGLETAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDAERKVYDYSKFEGEGGAVRTAAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTDYLARGIKEEAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CADH1_PSEMZ
Sequence: MGSLESERFVVDVAASNLDK
What is the function of this protein?
Involved in lignin biosynthesis.  Catalyzes the final step specific for the production of lignin monomers, like coniferyl alcohol, sinapyl alcohol and 4-coumaryl alcohol (By similarity).
What are the official names of this protein?
Probable cinnamyl alcohol dehydrogenase 1, CAD 1.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: SYN_XANOR
Sequence: MTVVSVEHALAGKLPEGGEVTVRGWVRTLRGSAGLAFINVTDGSCFAPIQVVANDTLPNFDEIKRLTSGCSLIAKGVLVKSQGKGQSFEIQASGVEIVGWVEDPLTYPIQPKPMTPEFLREVAHLRPRTNLFGAVTRIRNCLAQAVHRFFHQNGFNWISTPIITTSDAEGAGQMFRVSTLDMVNLPRDATGNVDFSRDFFGKETFLTVSGQLNVEAYCLALSKVYTFGPTFRAENSHTTRHLAEFWMIEPEIAFADLAEDARLAEQFLKYVFRAVLDERGDDLAFLAERVDKNAISKLEAFINAPFEQIDYTDAVKLLQHAGKTFDFPVEWGLDLQTEHERWLTEEHIGRPVVVTNYPEHIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLDVLDARMAQFGLDKEHYSWYRDFRRYGSVPHAGFGLGFERLVVYVCGLSNIRDAIPYPRAPGSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNNC2_MELGA
Sequence: PSMTDQQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVTEEEIEDLMKDSDKNNDGRIDFDEFLKMMEGVQ
What is the function of this protein?
Troponin is the central regulatory protein of striated muscle contraction.  Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C.  The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
What are the official names of this protein?
Troponin C, skeletal muscle.
What is the protein family that this protein belongs to?
Belongs to the troponin C family.