PharMolix/UniProtQA huggingface dataset:
Protein: SCPR_EMENI
Sequence: MNTMNNMHLYADSLGIHPADHYPTMNEIETTDNTYPRYTSPPHPSILHHPQAPEPAPPRAQTAHPPAWALTSQSGYQMNEPSLSLTPEHRPAAGPPNGPNLNHDSDPRRPARRQQPCGVGTTRPLPGCPGQGQEPSRRRTTFTDSISNPDSTIRCWDHGCEGRKFSSVGNYRRHLREKNGQAKMHPCPDCGRVFTRSTARNFHRQSGTCGLIPSQLMLQMGMGMQLQVQMQPVSQHSLASGHPPAFNLAPPVLLEPLADWSEPSQMDLYAASGVVFD
What is the function of this protein?
C2H2-type zinc-finger transcription factor that controls the expression of the nonribosomal peptide synthases inpA and inpB, as well as of the other inp cluster-associated genes (PubMed:20952652, PubMed:27294372).  Mediates also the expression of the asperfuranone biosynthesis gene cluster by binding to the afoA promoter (PubMed:20952652).  Probably recognizes the 5'-CT/C/AAAAGGAT/AT/GG/CA-3' motif in the promoters of teget genes (PubMed:20952652).
What are the official names of this protein?
C2H2-type zinc-finger transcription factor, Fellutamide B biosynthesis cluster protein F, Inp $cluster regulator scpR, Secondary metabolism cross-pathway regulator.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBEY_SHIFL
Sequence: MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCHL1_MACFA
Sequence: MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEDSLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEGTLLQDAAKVCREFTEREQGEVRFSAVALCKAA
What is the function of this protein?
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins.  This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin (By similarity).  Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity).  The homodimer may have ATP-independent ubiquitin ligase activity (By similarity).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, Ubiquitin thioesterase L1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. Nucleus. Note=Found both cytoplasmic and nuclear in cytotrophoblasts and decidual cells.
Protein: WDR73_HUMAN
Sequence: MDPGDDWLVESLRLYQDFYAFDLSGATRVLEWIDDKGVFVAGYESLKKNEILHLKLPLRLSVKENKGLFPERDFKVRHGGFSDRSIFDLKHVPHTRLLVTSGLPGCYLQVWQVAEDSDVIKAVSTIAVHEKEESLWPRVAVFSTLAPGVLHGARLRSLQVVDLESRKTTYTSDVSDSEELSSLQVLDADTFAFCCASGRLGLVDTRQKWAPLENRSPGPGSGGERWCAEVGSWGQGPGPSIASLGSDGRLCLLDPRDLCHPVSSVQCPVSVPSPDPELLRVTWAPGLKNCLAISGFDGTVQVYDATSWDGTRSQDGTRSQVEPLFTHRGHIFLDGNGMDPAPLVTTHTWHPCRPRTLLSATNDASLHVWDWVDLCAPR
What is the function of this protein?
May play a role in the regulation of microtubule organization and dynamics (PubMed:25466283).
What are the official names of this protein?
WD repeat-containing protein 73.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR73 family.
Protein: URE3_BURCJ
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPEAVAFITAALMEAARDGRTVAEVMHYGTTLLTRDDVMDGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_ARCAU
Sequence: MSMVYFNIFMAFTVSFVGLLMYRSHLMSSLLCLEGMMLSLFVMMSMTILNNHFTLASMAPIILLVFAACEAALGLSLLVMVSNTYGTDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS12_SYMTH
Sequence: MPTINQLVRQGRKKLTEKSASPALKGNPFKRGVCTVVKTTTPKKPNSALRKIARVRLSNNIEVTAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDAAGVANRMQGRSKYGAKRPKAGKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: HRCA_COREF
Sequence: MASATEKRRYEVLRAIVADYIESQEPVGSKALLERHKLNVSSATIRNDMSVLESDGYIVQEHASSGRVPTEKGYRLFVDSIHDIKPLSLAERRAILGFLEGGVDLEDVLRRSVQLLSQLTHQAAVVQLPTLKTARVKHCEVVSLSPVRLLLVLITDTGRVDQRNVELDEPLEADQVTVLKDLLNGALAEKTLTDASEALQELSRNAPSDIRSTMEKCSGVLVATLVEQPSDRLILAGASNLTRLTRETAASVPMVLEALEEQVVMLKLLSNVTDLDHVTVHIGEENEDLQLRSASVVTTGYGSAGNTLGGLGVVGPTYMDYPGTISKVSAVARYVGRVLAGE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: UREF_AGRVS
Sequence: MTIALDTLGLIRLMTWLSPAFPVGGFAYSGGLEKAVEDGLIDGGGTATGRQEALLAWLTSLLDHGTIWNDAVLLAEAWRVWNVPQSLTEVSDLALALAGSRERYQETTALGAAFREAARAWADPLSALSPNPVAYPVAVGAVGASQGIGCEAVLAAYLHAALSQQVSAGIRLSLIGQTGGLAILSRLEAPVARLAARAVQTGLDDLGSATIAADIVSARHEGQSVRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_MYCA9
Sequence: MAVVTMKQLLDSGAHFGHQTRRWNPKMKRFIFTDRNGIYIIDLQQTLTYIDKAYEFVKETVAHGGSVMFVGTKKQAQEPIAEEATRVGMPYVNQRWLGGMLTNFSTVHKRLQRLKELESMEQTGGFEGRTKKEILMLTREKNKLERSLGGIRDMQKVPSAIFVVDTNKEHLAVAEARKLNIPIIAILDTNCDPDVVDYPIPGNDDAIRSAALLTKVVASAIAEGLQARSGLAGGDEKPEAGEPLAEWEQELLASAVATTDEASAPSAAATETTTEEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: COAD_CHLL3
Sequence: MKKKAIYPGTFDPFTNGHLDVLERALTIFEEVTVLIAENSNKNTLFTVEERMDAIREITIGMDGLHVEVLHDGLLAEYARDVGANAIIRGVRQVKDFEYEFQLSLLNRHLNPDVTTVFLMPNVKYTYIASSIIKEVAMLGGDVSKFVHPSVLSMLHRKRKELKPNTTS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_STRT1
Sequence: MAVFEKVQEIIVEELGKDAEEVKVETTFDELDADSLDVFQVISEIEDEFDIQIETEEGLNTVGDLVAYVEEKTK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3E2_ECHOC
Sequence: MMQVLLVTICLAVFPYQGSSIILESGNVNDYEIVYPQKVTALPIEAILQPEQKYEDAMQYEFEVNGEPVVLHLEKNKNLFTKDYSETHYSPDGREITTKPLIEDHCYYHGRIQNDAHSTASISACNGLKGHFKLQGETYLIEPLKIPDSEAHAVYKYENIEKEDEALKMCGVKHTNWESDEPIKEASQLFATSEQHRFRERYIEFFIVVDQRMYNKHNNDSAAIRTWIFEMLNTVNEIYLPWNIHVPLVGLEFWTQGDLINVVSSADKTLDSFGEWRRRDLLNRKAHDNAHLITAMHFDAQTLGLAYTGSMCHPKYSTGVFQDSSEINIFVAITLAHELGHNLGISHDVPSCTCQTKACIMSPYLSDQPTKLFSNCSEIQYERFLTQRNPKCMINKPLRTDIISPPVCGNGLLEREEECDCGSPENCRDPCCDAASCKLHSWVECESGECCDQCRFKRAGTLCRPARDDCDMAESCSGHSADCPIDGFHANGQPCSHNLGYCYNGKCPLTLYQCRAFLGKDVVGVQESCFQYNRLGNTYAYCRKENGRKIPCAPKDEKCGRLYCSYKSFGDYISCLPCYRANEEDKGMVDEGTKCGEGKVCSNGYCVDLNVAY
What is the function of this protein?
Snake venom zinc metalloprotease that possesses high hemorrhagic activity.  It inhibits collagen-induced platelet aggregation and activates prothrombin (F2).
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like EoVMP2, Haemorrhagic 56 kDa metalloproteinase, Snake venom metalloproteinase, SVMP, Zinc metalloproteinase-disintegrin-like Eoc22.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOW_STAAW
Sequence: MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYERV
What is the function of this protein?
Catalyzes the transformation of pimelate into pimeloyl-CoA with concomitant hydrolysis of ATP to AMP.
What are the official names of this protein?
6-carboxyhexanoate--CoA ligase, Pimeloyl-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the BioW family.
Protein: GATA_LEPIN
Sequence: MNEILKKSYVELKDSLNSGKISSTELVSACINRIREVDGAVKAFLYLDEKKVLNSAEESDKRRKEGKPLSEFDGMPVAIKDNICIRDTITSCSSKILENYKSPFHATVVEKLLEKGFILFPRTNMDEFAMGSSTENSAFQTTRNPFDLERIPGGSSGGSAAAVAASMVPLALGSDTGGSVRQPASLCGLYGLKPTYGTVSRYGLVAYASSLDQIGPFSRELQGCIDLYSVISGKDVRDSTSIHRPKFSASDVQPQDFKGLKVGVIKMTPEIQSEVVKSYDKVLNQLKEKGATLVDLDFSKFGFAIPIYYIIATAECSSNLSRFDGIRFGSRKDKTGKLEDLFVDSRTEGFGPEVKRRILLGTFSLSAGYYDAYYGTAQKARALIRKEYESFFSKVDCILQPTSPTTAFKIGEKTKDPIQMYKADIWTTSVNLAGLPAMSVPMGADQKGLPIGLQITTPHFQEGKLFGIALALSTLEGMNIQFPESIK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: DNAK_CUPNH
Sequence: MGKIIGIDLGTTNSCVAILEGNTPKVIENSEGARTTPSIIAYMEDGEILVGAPAKRQAVTNPRNTLYAVKRLIGRKFEEKEVQKDIGLMPYSIVKADNGDAWVSVRDQKLAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAFGMDKNEKGDRKIAVYDLGGGTFDISIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRIIDYIISEFKKDQGVDLSKDVLALQRLKEAAEKAKIELSSSQQTEINLPYITADASGPKHLNLKMTRAKLESLVEELITRTIEPCRIAIKDAGVKVSDIDDVILVGGMTRMPKVQEQVKEFFGKEARKDVNPDEAVAVGAAIQGSVLSGDRTDVLLLDVTPLSLGIETLGGVMTKMITKNTTIPTKHAQVFSTADDNQPAVTIKVFQGEREMASGNKLLGEFNLEGIPPAARGTPQIEVSFDIDANGILHVGAKDKATGKENRITIKANSGLSEDEIQRMVKDAEANAEEDKKARELADARNQADALIHSTKKALTEYGDKLEAGEKEKIEAAIKELEDAARGGDKAEIDAKVNALSEVSQKLGEKVYADMQAKAGEGATAGAAAGAGAAGGQQAQPQDDNVVDAEFKEVNDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PACS1_HUMAN
Sequence: MAERGGAGGGPGGAGGGSGQRGSGVAQSPQQPPPQQQQQQPPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIVLPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKIKSTWIKNQDDSLTETDTLEITDQDMFGDASTSLVVPEKVKTPMKSSKTDLQGSASPSKVEGVHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGGQSYLSSILRFFVKSLANKTSDWLGYMRFLIIPLGSHPVAKYLGSVDSKYSSSFLDSGWRDLFSRSEPPVSEQLDVAGRVMQYVNGAATTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHSGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKAT
What is the function of this protein?
Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs.  Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits.  Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN.  Required for normal ER Ca2+ handling in lymphocytes.  Together with WDR37, it plays an essential role in lymphocyte development, quiescence and survival.  Required for stabilizing peripheral lymphocyte populations (By similarity).
What are the official names of this protein?
Phosphofurin acidic cluster sorting protein 1, PACS-1.
What is the protein family that this protein belongs to?
Belongs to the PACS family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Note=Localizes in the perinuclear region, probably the TGN.
Protein: RL24_RICPU
Sequence: MIKLKVKKGDEVVVITGKHKGKKGKILKVFPEDSKVIVSGVNVVKKHTKSNQMSEGGIITKELPIHISNIAHIDPKTGNPTKVAFKFLEDGSKVRVAKKSGEIIGKEGK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SYV_SALAI
Sequence: MPAKASLEGIEQVWSRVWEQNGTYRFDRSVTRDEVYSIDTPPPTVSGALHVGHVFSYTHADAIARFQRMRGKMVFYPMGWDDNGLPTERRVQNYYGVQCDPSLPYDPGYTPPTEPPGRPQPISRRNFVELCRNLTKIDEQAFEALWRHLGLSVDWSLTYATIDDRSRAISQRAFLRNLARGEAYLADAPTLWDVSFRTAVAQAELEDRERQGHYYRLSFTSAAGDTIHVETTRPELLPACVALVAHPDDKRYQHLFGSTAVTPVFRVPVPIKAHPLAQPDKGSGIAMICTFGDLTDVLWWRELALPTRPVMGRDGRLLPEPPPGITNAEAVAAYRTLAGLTAFSAKAKMVELLRASGDLAGDPQPTAQAVKFYEKGDKPLEIVTTRQWYVRNGGRNAQLRAALIRRGRELSWSPRFMRSRYENWVEGLAGDWIISRQRFFGVPIPVWYPLDDSGEPDYERPILPDDAALPVDPSSDTPTGYHDSQRHQPGGFMADPDVMDTWATSSLTPEIAGGWTVDDDLFGRVFPMDLRPQAHEIIRTWLFATMLRSHQEFDRLPWRTALLSGWILDPDRKKMSKSKGNSVVTPMSLLAEYGSDAVRYWAVSGRPGTDTAFDTGQMKIGRRLAIKILNATKFVLRFESPTLRAPHVAHVTEPLDRSMLARLADVVAAATTGFTQYDYTRSLECTEHFFWSFCDDYLELVKERAYGNPDDPAVRSAHAALALALRTLLRLFAPMLPFVTEEAWSWWQEGSVHRASWPARQELVGDADGVDRANRIDETNGSDEAVEDLLGLASGVLAAIRRAKSEAKQSMRASVARLTLRGRASDLAAFALVSRDVRAAGVVRDVDTAEADVPLTPEITLG
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_STAA2
Sequence: MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGLRLQNRKLRRPDLTFATLDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSDEQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQTKPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTICNMAIEGGAKYGIIQPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELDVSTLEPQVTWGTNPEMGVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLGSCTNARLSDLIEASHIVKGNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWREPGCSMCLGMNPDQVPEGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAIHGKFVDVRKVVV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: NTPPB_PSE14
Sequence: MPSLLLASSSSYRRELLTRLRLPFTCKSPDIDESHRLDETAHDLVRRLALEKARALAGEYPHHLIIGSDQVAVLNGQILGKPHTFERALEQLTAASGTSVTFLTGLALLNSSTGEHQVDCVPFTVHMRELDQASIERYLHAEQPYDCAGSFKAEGLGVSLFRSTEGSDATSLIGLPLIRLVDMLIKEGVSVP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAI_ANGLY
Sequence: MTASYLPSIFVPLVGLVFPAITMASLSIYIEQDEIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: G6PD2_MYCTU
Sequence: MKPAHAAASWRNPLRDKRDKRLPRIAGPCGMVIFGVTGDLARKKVMPAVYDLANRGLLPPTFSLVGFARRDWSTQDFGQVVYNAVQEHCRTPFRQQNWDRLAEGFRFVPGTFDDDDAFAQLAETLEKLDAERGTGGNHAFYLAIPPKSFPVVCEQLHKSGLARPQGDRWSRVVIEKPFGHDLASARELNKAVNAVFPEEAVFRIDHYLGKETVQNILALRFANQLFDPIWNAHYVDHVQITMAEDIGLGGRAGYYDGIGAARDVIQNHLMQLLALTAMEEPVSFHPAALQAEKIKVLSATRLAEPLDQTTSRGQYAAGWQGGEKVVGLLDEEGFAEDSTTETFAAITLEVDTRRWAGVPFYLRTGKRLGRRVTEIALVFRRAPHLPFDATMTDELGTNAMVIRVQPDEGVTLRFGSKVPGTAMEVRDVNMDFSYGSAFAEDSPEAYERLILDVLLGEPSLFPVNAEVELAWEILDPALEHWAAHGTPDAYEAGTWGPESSLEMLRRTGREWRRP
What is the function of this protein?
Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase 2, G6PD 2.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
Protein: DAPH_BACCN
Sequence: MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPGTVQAFVNKKAGVLFGEWSEIKVILEENKKHIADYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAIVTEDVPPYTVVAGTPARVIKKIDEKTKAKTEIKQELRQLNPEK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: VP4_ROTS1
Sequence: MASLIYRQLLTNSYTVDLSDEIQEIGSTKSQNVTINPGPFAQTGYAPVNWGPGEINDSTTVEPLLDGPYQPTTFNPPVDYWMLLAPTTPGVIVEGTNNTDRWLATILIEPNVQSENRTYTIFGIQEQLTVSNTSQDQWKFIDVVKTTANGSIGQYGPLLSSPKLYAVMKHNEKLYTYEGQTPNARTAHYSTTNYDSVNMTAFCDFYIIPRSEESKCTEYINNGLPPIQNTRNVVPLSLTARDVIHYRAQANEDIVISKTSLWKEMQYNRDITIRFKFANTIIKSGGLGYKWSEISFKPANYQYTYTRDGEEVTAHTTCSVNGVNDFSFNGGYLPTDFVVSKFEVIKENSYVYIDYWDDSQAFRNVVYVRSLAANLNSVMCTGGSYNFSLPVGQWPVLTGGAVSLHSAGVTLSTQFTDFVSLNSLRFRFRLAVEEPHFKLTRTRLDRLYGLPAADPNNGKEYYEIAGRFSLISLVPSNDDYQTPIANSVTVRQDLERQLGELREEFNALSQEIAMSQLIDLALLPLDMFSMFSGIKSTIDAAKSMATNVMKKFKKSGLANSVSTLTDSLSDAASSISRGSSIRSIGSSASAWTDVSTQITDISSSVSSVSTQTSTISRRLRLKEMATQTEGMNFDDISAAVLKTKIDKSTQISPNTIPDIVTEASEKFIPNRAYRVINNDDVFEAGIDGKFFAYKVDTFEEIPFDVQKFADLVTDSPVISAIIDFKTLKNLNDNYGITKQQAFNLLRSDPRVLREFINQDNPIIRNRIEQLIMQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: SYDND_CHLP8
Sequence: MSKEPTAAAGLQNRFRTHYCGLLNRDSEGAGVKLGGWVHRIRDHGGLIFIDLRDHTGICQLVIQPESGELFRIAEGLHSESVISAEGSVVLRSDETVNPRLASGAIEVVVSAIKIESAAHPLPFPVADYMPTSEELRLKYRFLDLRRERLHENIIFRSQLTAAVRKYLTDLDFIEIQTPILTSSSPEGARDFLVPSRLHPGKFYALPQAPQQFKQLLMVSGFPRYFQIAPCFRDEDARADRSPGEFYQVDIEMSFVEQDDLFVILEGMFKHLVETMTTKRIAQYPFPRISYKDVMNRYGSDKPDLRIPIEIQDVTELFVNSGFKVFASNTKEGCCVKAMVLKGMGNESRLFYDKAEKRARELGSAGLAYIQFKEEAPKGPVVKFLKEEEMAALKEQLGIETGDVVFFGAGKWEQTCKIMGGMRNYFADVFPLDRDELSFCWIVDFPMFEYNEEDKKIDFSHNPFSMPQGEMEALEQHSPLDILAYQYDIVCNGIELSSGAIRNHRPDIMYKAFEIAGYPHDEVDARFGHMIEAFKHGAPPHGGIAPGLDRLVMILRDEQNIREVIAFPMNQSAQDLMMAAPSEVTAQQLKELHIKVELPEEEA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.