PharMolix/UniProtQA huggingface dataset:
Protein: DUT_WOLSU
Sequence: MSELKKMKIRLLKLHPNAVIPAYQSAGAAGFDLCCVESLEIPPLGRALVSTGLALALEEGYELQIRPRSGLALKHGITVLNTPGTVDSDYRGEIKVILINLGAESFSIQAGDRIAQGVVSRLSIAELCEVESLDETARGAGGFGSTGKS
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: FABH1_DEIRA
Sequence: MKSIGITAIGMYVPERVVHNHEFESRMGIEDGWIESRSGIRERRFSAPGEFASHIGAKAVQDMLARDPDALKDVDLVIYATCTPDAMFPSTAALVAGQVGLTGVGAYDLSTACSGFVYALSMARGMILGGSAKNVLVLGGEVLSKALDQDDRDTAILFGDGCGCAVVGEVPAGYGFQDFVLGADSAGGPALYISNLADQFPDGQIMRGVPTMNGREVFKFAVRVLGDSGTQALQKSGLSNADVDWLIPHQANIRIIEAATQRFGIPMEKTVINLDRYGNTSAGTVPLALYEAVNDGRIQGGQQLLMVVFGGGLSWAACTMKWWGGRPSLHAQVAQPAEVPA
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III 1, Beta-ketoacyl-ACP synthase III 1, KAS III 1, 3-oxoacyl-[acyl-carrier-protein] synthase 3 1, 3-oxoacyl-[acyl-carrier-protein] synthase III 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOC_BPP1
Sequence: MRHISPEELIALHDANISRYGGLPGMSDPGRAEAIIGRVQARVAYEEITDLFEVSATYLVATARGHIFNDANKRTALNSALLFLRRNGVQVFDSPELADLTVGAATGEISVSSVADTLRRLYGSAE
What is the function of this protein?
Antitoxin phd binds to its own promoter repressing its expression; toxin doc acts as a corepressor or derepressor depending on the ratio, repressing or inducing expression.
What are the official names of this protein?
Protein kinase doc, Death on curing protein, Toxin doc.
Protein: IGFL_MOUSE
Sequence: MKIRNACAVLIEVLLFILEGVTGARKISTFSGPGSWPCNPKCDGRTYNPSEECCVHDTILPFKRINLCGPSCTYRPCFELCCPESYSPKKKFIVKLKVHGERSHCSSSPISRNCKSNKIFHGEDIEDNQLSLRKKSGDQP
What is the function of this protein?
Probable ligand of the IGFLR1 cell membrane receptor.
What are the official names of this protein?
Insulin growth factor-like family member.
What is the protein family that this protein belongs to?
Belongs to the IGFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_CLOBJ
Sequence: MLVMNLQLFAHKKGVGSSKNGRDSEAKRLGVKCSDGQFVLAGNILVRQRGTKIHPGLNVGRGGDDTLFAKIDGVVKYERLGRDKKKASVYPVEVEEVVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CH601_MYCS2
Sequence: MSKQIEFNETARRAMEAGVDKLADAVKVTLGPRGRHVVLAKSFGGPQVTNDGVTIAREIDLEDPYENLGAQLVKSVATKTNDVAGDGTTTATVLAQALVRAGLRNVAAGANPIALGSGISKAADAVSEALLASATPVDDKKAIAQVATVSSRDEQVGELVGEAMTKVGHDGVVTVEESSTLETYLEVTEGVGFDKGFLSAYFVTDFDSQEAVLEDALVLLHRDKISSLPDLLPLLEKVAEAGKPLLIVAEDVEGEALSTLVVNAIRKTLKAVAVKAPFFGDRRKAFLDDLAIVTGGQVVNPDVGLLLREVGLEVLGSARRVVVNKDSTVIVDGGGTAEAIADRVKQIKSEIETTDSDWDREKLQERLAKLAGGVAVIKVGAATETDLKKRKEAVEDAVAAAKAAVEEGIVTGGGAALVQARSAVEKLRGELSGDEALGVDVFASALSAPLYWIATNAGLDGSVVVNKVSELPKGQGFNAATLEFGDLVSAGVVDPAKVTRSAVLNAASVARMILTTETAVVDKPADEDEHGHGHHHGHAH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_RIPO1
Sequence: MSHKVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKAAQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CCD22_HUMAN
Sequence: MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLAMSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPAGDSAILLRAIGSQIRDQLALPWVPPHLRTPKLQHLQGSALQKPFHASRLVVPELSSRGEPREFQASPLLLPVPTQVPQPVGRVASLLEHHALQLCQQTGRDRPGDEDWVHRTSRLPPQEDTRAQRQRLQKQLTEHLRQSWGLLGAPIQARDLGELLQAWGAGAKTGAPKGSRFTHSEKFTFHLEPQAQATQVSDVPATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGVSFVQAESECRHSKLSTAEREQALRLKSRAVELLPDGTANLAKLQLVVENSAQRVIHLAGQWEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSELETLPRDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTDELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETELGKKTLSNLEKIREDYRALRQENAGLLGRVREA
What is the function of this protein?
(Microbial infection) The CCC complex, in collaboration with the heterotrimeric retriever complex, mediates the exit of human papillomavirus to the cell surface.
What are the official names of this protein?
Coiled-coil domain-containing protein 22.
What is the protein family that this protein belongs to?
Belongs to the CCDC22 family.
What are the subcellular locations of this protein?
Endosome.
Protein: LCNB_LACLC
Sequence: MKNQLNFNIVSDEELAEVNGGSLQYVMSAGPYTWYKDTRTGKTICKQTIDTASYTFGVMAEGWGKTFH
What is the function of this protein?
Kills Lactococci by dissipating the membrane potential of the cells.
What are the official names of this protein?
Bacteriocin lactococcin-B, LCN-B.
What are the subcellular locations of this protein?
Secreted.
Protein: LEUC_SYNSC
Sequence: MSSGTLYDKVWDLHRVAELPGGSTQLFVGLHLIHEVTSPQAFSALKDKGLLVRCPERTVATVDHIVPTTSQQRPFADPLAEEMLSTLERNCQEYGIPLNNIGSGRQGIVHVIAPELGLTQPGMTVACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQSLAMNKLKVRRIQVNGLLPEGVSAKDLILHVIRHLGVKGGVGYAYEFAGSAIEALSMEERMTLCNMAIEGGARCGYVNPDQVTFEYLKGRPHAPEGDAWTRAVAWWSSLATDANATVDDEVVFDAAAIPPTVTWGITPGQGLGIDETVPSLDQLDPGERPIAEEAYRYMDLQPGTAIAGVPVDVCFIGSCTNGRLSDLRAAADVARGRQVAEGIKAFVVPGSEQVAKAAEAEGLDAVFRAAGFEWREPGCSMCLAMNPDRLEGRQISASSSNRNFKGRQGSASGRTLLMSPAMVAAAAVNGRVTDVRTLISPSAS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: UBIE_ECOSE
Sequence: MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: FTHS_LISMC
Sequence: MSNKVKSDIEIASKAEILPVTTIAEHLGLDADALELYGKYKAKLSYDTIHSLKDKEPGKLVLVTAINPTPAGEGKSTVTVGLGDALSKKDKKTVIALREPSLGPTMGIKGGATGGGYAQVIPMEDINLHFTGDFHAITAANNALSAFIDNHMQQGNDLDIDGRRIVWKRVVDLNDRALRKVVVGLGGPIQGVPREDGFDITVASEIMAIICLASDLKDLKKRLSEIVIGYNYKKEPITVGEMGYEGALTLLLKDALKPNLVQTLEHTPAIVHGGPFANIAHGCNSVSATSTALRLGEYVVTEAGFGADLGAEKFLDIKVPALGKAPDCVVIVATIRALKMHGGALKTELSEENVDALAKGFTNLQKHTESIQTFGIPYVVAINKFITDSDAEVAKLEALCEEHGIPFSLTEVWEKGGDGGLELADKVIAAVESGEADYKRIYDDAWSIEEKLEAIVTKVYGGIGVELSSKAQKQIVEFKKYGWDRYPICMAKTQYSLSDDPTLLGRPTDFVIHIREFIPKLGAGFVVALTGDVMTMPGLPKKPAALNMDVDENGNAQGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: VP4_ROTTU
Sequence: MASLIYRQLLANSYAVDLSDEIDIIGSEKTQNVTINPGPFAQTGYAPVNWGPGETNDSTTIEPILDGPYPPTTFNPPTGYWMLLSPLEAGVVVEGTNNSDRWLATILIEPNVAAETRTYTLFGVQEQISISNTSSTKWKFVDLVKTSLTGTYSQYGPLLSDTKLYGAMKYSGRIYTYEGETPNAATGYYSTTNYDSVNMTAFCDFYIIPRSQESTCTNYINNGLPPIQNTRNVVPVSLASRAIISHRAQANEDIIVSQTSLWKEMQYNRDITIRFKFANAIVKSGGLGYKWSEISFKPANYQYTYVRDGEEVTAHTTCSVNGINDFSYNGGSLPTDFGISRYEVIKENSYVYVDYWDDSQAFRNMVYVRSLAADLNSVMCTGGSYNFALPVGQWPVMTGGAVSLHSAGVTLSTQFTDFVSLNSLRFRFRLSVEEPPFSIVRTRISGLYGLPAADPNNGNEYYEIAGRFSLISLVPSNDDYQTPIMNSVTVRQDLERQLGELREEFNALSQEIAMSQLVDLALLPLDMFSMFSGIKSTIDAAKSMATNVMKKFKKSSLASSVSTLTDSLSDAASSMTRNSSIRSVGSSISAWTDVSSQLTDASASTSTIATQTATISRRLRLKEIATQTEGMNFDDISAAVLKTKIDRSVQISPSTLPDIVTEASEKFIPNRAYRVINNDEVFEAGMDGRFFAYRVETFEEIPFDVQRFADLVTDSPVISAIIDFKTLKNLNDNYGITRDQAFNLLRSDPRVLREFINQDNPIIRNRIEQLILQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: ILVN_ECOL6
Sequence: MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ
What are the official names of this protein?
Acetolactate synthase isozyme 1 small subunit, Acetohydroxy-acid synthase I small subunit, AHAS-I, ALS-I.
What is the protein family that this protein belongs to?
Belongs to the acetolactate synthase small subunit family.
Protein: FOS_RAT
Sequence: MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTPSTGAYARAGVVKTMSGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPNDLGFPEEMSVTSLDLTGGLPEATTPESEEAFTLPLLNDPEPKPSLEPVKNISNMELKAEPFDDFLFPASSRPSGSETARSVPDVDLSGSFYAADWEPLHSSSLGMGPMVTELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL
What is the function of this protein?
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor.  On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling (By similarity).  Has a critical function in regulating the development of cells destined to form and maintain the skeleton.  It is thought to have an important role in signal transduction, cell proliferation and differentiation.  In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A.  This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Protein c-Fos, Cellular oncogene fos, Proto-oncogene c-Fos.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Cytoplasm, cytosol. Note=In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30 (By similarity).
Protein: MELPH_HUMAN
Sequence: MGKKLDLSKLTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQPYQLLVNSKRQCLECGLFTCKSCGRVHPEEQGWICDPCHLARVVKIGSLEWYYEHVKARFKRFGSAKVIRSLHGRLQGGAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEARDSPQSLTDESCSEKAAPHKAEGLEEADTGASGCHSHPEEQPTSISPSRHGALAELCPPGGSHRMALGTAAALGSNVIRNEQLPLQYLADVDTSDEESIRAHVMASHHSKRRGRASSESQIFELNKHISAVECLLTYLENTVVPPLAKGLGAGVRTEADVEEEALRRKLEELTSNVSDQETSSEEEEAKDEKAEPNRDKSVGPLPQADPEVGTAAHQTNRQEKSPQDPGDPVQYNRTTDEELSELEDRVAVTASEVQQAESEVSDIESRIAALRAAGLTVKPSGKPRRKSNLPIFLPRVAGKLGKRPEDPNADPSSEAKAMAVPYLLRRKFSNSLKSQGKDDDSFDRKSVYRGSLTQRNPNARKGMASHTFAKPVVAHQS
What is the function of this protein?
Rab effector protein involved in melanosome transport.  Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
What are the official names of this protein?
Melanophilin, Exophilin-3, Slp homolog lacking C2 domains a, SlaC2-a, Synaptotagmin-like protein 2a.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAM7_YEAST
Sequence: MAANSVGKMSEKLRIKVDDVKINPKYVLYGVSTPNKRLYKRYSEFWKLKTRLERDVGSTIPYDFPEKPGVLDRRWQRRYDDPEMIDERRIGLERFLNELYNDRFDSRWRDTKIAQDFLQLSKPNVSQEKSQQHLETADEVGWDEMIRDIKLDLDKESDGTPSVRGALRARTKLHKLRERLEQDVQKKSLPSTEVTRRAALLRSLLKECDDIGTANIAQDRGRLLGVATSDNSSTTEVQGRTNNDLQQGQMQMVRDQEQELVALHRIIQAQRGLALEMNEELQTQNELLTALEDDVDNTGRRLQIANKKARHFNNSA
What is the function of this protein?
Essential for proper morphogenesis of the vacuole.  May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.
What are the official names of this protein?
Vacuolar morphogenesis protein 7.
What are the subcellular locations of this protein?
Vacuole.
Protein: HFQ_BACP2
Sequence: MKPINIQDQFLNQIRKDNTFVTVFLLNGFQLRGQVKGFDNFTVLLETEGKQQLIYKHAISTFAPQKNVNLELE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RRT14_CANAL
Sequence: MSFNSNASKYQAENTVDKLFSNILHTSTTSKSVSKSKSKSKSKPKPISSTQLLVNQLQSTNTTANNNNTKRKKHNNNKRINKTLLEEKKFSKFIKYNHIKQKSNKSELDEKYLNKLVRKNINSLNKINKIDDLLIDEELNQIKQELLEENEFVGMGGGQLKGGKRLRKKLLNNTKQVIDEFDGFGEISSSNNNNKKKNSSYPGLTPGLAPVDYEEEDNE
What is the function of this protein?
Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
What are the official names of this protein?
Regulator of rDNA transcription 14.
What is the protein family that this protein belongs to?
Belongs to the RRT14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DCYD_SHIFL
Sequence: MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDEVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGGSNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: 3MGH_BACC1
Sequence: MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVREEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: SODC_KLULA
Sequence: MVNAVAVLKGDSSVSGIVRFEQESEDQQTKISWEITGNDANALRGFHIHTFGDNTNGCTSAGPHFNPFNKNHGAPEDEERHVGDLGNIPTDAQGISKGSLTDKHIKLLGPLSIVGRTVVVHAGQDDLGKGGDAESLKTGNAGARHACGVIGISNA
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADM2_HUMAN
Sequence: MARIPTAALGCISLLCLQLPGSLSRSLGGDPRPVKPREPPARSPSSSLQPRHPAPRPVVWKLHRALQAQRGAGLAPVMGQPLRDGGRQHSGPRRHSGPRRTQAQLLRVGCVLGTCQVQNLSHRLWQLMGPAGRQDSAPVDPSSPHSYG
What is the function of this protein?
May play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes.  Activates the cAMP-dependent pathway.
What are the official names of this protein?
Protein ADM2, Intermedin.
What is the protein family that this protein belongs to?
Belongs to the adrenomedullin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL34_LACDA
Sequence: MSTKRTYQPKKRHRSRVHGFMKRMATSNGRKVLARRRAKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MCIN_XENLA
Sequence: MQNRRKAFYKLCPNAMPDLSNRLSKKQSKTEKKLHKNIFAHTGPVTIYVDPPSSAVDSALATIDWQDLVDCNSVIQQDAAGGAITQQQDHCLSGEPDFDLQEFRDAVDQFIADQPSLMQPSLGPPEFQLPACNVPVFEPCMTNPLQAQPEHLLPINVQTIPSTEQYWRDVADHNQKALGDALVENNQLQVSLTEKQEEIVSLKEKNIQLNELANQAKHLSSVLDKLMKERTKQNSGATQGRLPVKRSLEDFYPQSNEPDSTQVDEILREISKKCNIALMGSDLSERKRPRLEPMDSMDWQEEGVTEIKMCGAFHGLKTSTGLNSVNLGDTDLEDVSFRTSIKEHSTIRTLAFPQGNAFTIRTSGGGYKFRWVPN
What is the function of this protein?
Transcription regulator specifically required for multiciliate cell differentiation.  Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis.  Activates genes required for centriole assembly (plk4, cep152) and genes specifically required for motile cilia formation (foxj1).  Also promotes the deuterosome pathway of centriole biogenesis by activating expression of ccdc67/deup1, but not its paralog cep63.
What are the official names of this protein?
Multicilin, Multiciliate differentiation and DNA synthesis-associated cell cycle protein, McIdas protein, Protein Idas.
What is the protein family that this protein belongs to?
Belongs to the geminin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMM_BRUMB
Sequence: MPRPENPIQLAVIGAAHGTRGEVRVKTFTGDPLAIADYGLLYDEQGKAYEILEARVAKTVVIVRFKGVNDRNAAEALNGTELFIDRSQLPDEELDEDEFFQTDLIGLEAVDGDGKSYGVVSAIFDFGGGDLIELSEKGKRPMLIPFTEAAVPEIDFDKGIIKVEPHAAGLIADEHDNPPHESGKKPKKP
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_COXBU
Sequence: MEVAAKLKYARISAQKARLVADQVRGLGAEQAVNLLRFSNKKAAALMKKVLDSAIANAEHNEGADIDELKVSTVMVDEGPSARRFHARARGRANQILKRTCHITVKVSDSQVEND
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL7_YERPA
Sequence: MSTITKDQILEGVAALSVMEIVELISAMEEKFGVSAAAVAAGPAAAVEAAEEQTEFDVVLASFGENKVAVIKAVRGATGLGLKEAKDLVESAPAVLKEGVNKDEAETLKKSLEEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RF1_STAAS
Sequence: MFDQLDIVEERYEQLNELLSDPDVVNDSDKLRKYSKEQADLQKTVDVYRNYKAKKEELADIEEMLSETDDKEEVEMLKEESNGIKAELPNLEEELKILLIPKDPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAESQGFKTEIVEASESDHGGYKEISFSVSGNGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEVEDVEIEIRNEDLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLYDMKVQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLGQIMEGHLEEIIDALTLSEQTDKLKELNNGEL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.