PharMolix/UniProtQA huggingface dataset:
Protein: ASTD_ECOLI
Sequence: MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVEQACRAARAAFPRWARLSFAERHAVVERFAALLESNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAWQQLEAMGGRPLLAPRLLQAGTSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDTFDEAIRMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate (Probable).  Also shows in vitro activity with decanal or succinic semialdehyde as the electron donor and NAD as the electron acceptor.  No activity is detected with NADP as the electron acceptor.  Therefore, is an aldehyde dehydrogenase with broad substrate specificity (PubMed:15808744).
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: RHAD_ECODH
Sequence: MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_XANP2
Sequence: MHDIKWIRDEPVGLITALVRRGGGSDEAKSAAEKLVAYLIGLDEQRRRTLTDLEGKLARRNAASKEIGQAKAQKDEERASRLMAEVANLKADIPTLEALAKDWEKSLDNALAAIPNAPLAEVPPGADEHDNVEKSRFGVARSYAFTPKQHFEVGEALGQMDFETAAKLSGARFVVNKGPLARLERALGQFFLDVHTGEHGYMEVNPPLLVRDDAMFGTAQLPKFREDQFFVNTVDGIEAISAETKGFETFSDEFKSKLTEAMSYQGRWLIPTAEVPLTNLVRESILSEEELPLRLTACTPCFRAEAGAAGRDTRGMIRQHQFTKVELVSITTPEKSAEEHERMLACAEAVLKKLDLHYRVVTLCTGDMGFASQKTYDIEVWLPGQGAFREISSCSVCGDFQARRMNARYRPAEGKGPRFVHTLNGSGVAVGRALVAVLETYQQENGAVTVPDALLPYMGGLKTIEKLK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDA_STRR6
Sequence: MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVTKTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLVGMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTKPLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSSGNGLYIEDESVVIRPKNGFGGIGGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKEGVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor.
What are the official names of this protein?
Probable dihydroorotate dehydrogenase A (fumarate), DHOD A, DHODase A, DHOdehase A.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_RHOP2
Sequence: MQETGVHNGAHGADKFGLKNLKGVYWNFAAPQLYEHALKNGEAVLSADGALCADTGEFTGRSPKDKFTVRDATTETTMWWGGNQSITAEQFETLYQDFLKHAEGMTLFAQDLYGGADPSFQIKTRVFTELAWHSLFIRTLLRRPDRAALESFVPELTLIDLPSFRADPKRHGCRSENVVAIDFARKIVLIGGTQYAGEMKKSVFTTLNYYLPEKGVMPMHCSANVGPQGDTAIFFGLSGTGKTTLSADPNRTLIGDDEHGWGKDGVFNFEGGCYAKCIKLSPEAEPEIFAASSRFGAVLENVVLDEITRKPDFDDGSKTENTRSAYPLESIPNASLTGRAGQPKNVVMLAADAFGVMPPIAKLTPAQAMYHFLSGYTAKVAGTERGVTEPEPEFSTCFGSPFLPRDPSVYGNMLRELIAKHDVDCWLVNTGWTGGIYGTGHRMPIKVTRALLTAALDGSLRNVEFRTDPYFGFAVPTSLHGVPSDILDPVKTWADKAAFDATARKLVGMFQKNFAKFEAQVDADVRAAAPDVKMAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLUP_BRUAB
Sequence: MATSIPTNNPLHTETSSQKNYGFALTSLTLLFFMWGFITCLNDILIPHLKNVFQLNYTQSMLIQFCFFGAYFIVSLPAGQLVKRISYKRGIVVGLIVAAIGCALFIPAASYRVYALFLGALFVLASGVTILQVAANPYVTILGKPETAASRLTLTQAFNSLGTTVAPVFGAVLILSAATDATVNAEADAVRFPYLLLALAFTVLAIIFAILKPPDVQEDEPALSDKKEGSAWQYRHLVLGAIGIFVYVGAEVSVGSFLVNFLSDPTVAGLSETDAAHHVAYFWGGAMVGRFIGSAAMRYIDDGKALAFNAFVAIILLFITVATTGHIAMWSVLAIGLFNSIMFPTIFSLALHGLGSHTSQGSGILCLAIVGGAIVPLIQGALADAIGIHLAFLMPIICYAYIAFYGLIGSKS
What is the function of this protein?
Intake of glucose and galactose.
What are the official names of this protein?
Glucose/galactose transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU3_COREF
Sequence: MKLAVIGGDGIGPEVTDEALKVLRALRADIETTDLDLGARRYLRNGELLTDEDLALLREHDAILLGAIGAPGSVPPGVLERGLLLKLRFALDHHVNLRPSKLYEGVESPLKNPGEIDFVVVREGTEGAYTGNGGAIRVGTPHETANETSVNTRYGAERVIRYAFELAQSRRRHLTLVHKTNVLVHGGGLWQRTVDEVAREYPEVTVDYNHIDAATIYLVTDPSRFDVIVTDNLFGDILTDEAGAISGGIGLAASGNIDATGTNPSMFEPVHGSAPDIMGKGIADPTAAILSAAMMLRHLGDEANAVRIEEAVARDVAGRDPEAPISTTEVGDRIAAAVVA
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL6_ARATH
Sequence: MRSSDHMAFAGVLPIVFLLILSSADLAASQSQPGPTNQPYNYGRLSPAMAVIVVILIAALFFMGFFSIYFRHCSGVPDAGVSPAGGARSRATVNAAARGLDVSVVETFPTFLYSDVKTQKLGKGELECAICLNEFEDDETLRLLPKCDHVFHPHCIDAWLEAHVTCPVCRANLAEQVAEGESVEPGGTEPDLELQQVVVNPEPVVTAPVPEQLVTSEVDSRRLPGVPVDLKRVKFSRSHTTGHSVVQPGECTERFTLRLPEDVRKRIMKDWKLNRTNSLLVLPRGGSSRRGKPIDRSRARSDRWLFRKTPSFLWRSRDDGSIRLGATGSVRASAVPNSTGSDSVRAGDRWAFLRNASFLWRNSSVHVPRGGVNKDGEGTSVKSTGASGSTSGSVRLPV
What is the function of this protein?
E3 ubiquitin-protein ligase able to catalyze polyubiquitination with ubiquitin-conjugating enzyme E2 UBC8 in vitro.  May be involved in the plant C/N response and the early steps of the plant defense signaling pathway.
What are the official names of this protein?
E3 ubiquitin-protein ligase ATL6, RING-H2 finger protein ATL6, RING-type E3 ubiquitin transferase ATL6.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DAPB_CHLTA
Sequence: MRVADSIMKKSIGLVGDTGRMGVLLTQALLCRPHCFLGKGFSRRSQTSLEEVVTENDILIDFSSPEVTSLLLDFLLKTPRPVIIGTTGFTNDSGVKTKLSALSEYVPVVVCANTSLGAYVQKRLAAFAAKLFSTSYDVRILETHHRAKADAISGTAISLAEAIRSAKAESYEEEPEPFIEMHGSRLGNVCGEHEVSFVGEDERFVIRHEVFSRRVFSGGVLLILEKIMGEGLPKGYYTSDVLYESLFQEKVFG
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CISY1_RHITR
Sequence: MTEQSAKLTWGEKTVDLPVKTGTIGPSVIDIGALYKNTSTFTYDPGFTSTASCESSITFIDGDEGVLLHRGYPIEQLAEHGDFLEVCYLLLYGELPTAAQKKDFDYRVVHHTMVHEQMSRFFTGFRRDAHPMAVMCGCVGALSAFYHDSTDITDPHQRMVASLRMIAKMPTLAAMAYKYHIGQPFVYPKNDLDYASNFLRMCFAVPCEEYVVNPVLARAMDRIFILHADHEQNASTSTVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLTEIGTVDRIPEYIARAKDKNDPFRLMGFGHRVYKNYDPRAKIMQKTAHEVLGELGIKDDPLLDIAIELERIALTDDYFIEKKLYPNVDFYSGITLKALGFPTTMFTVLFALARTVGWIAQWNEMIEDPDQRIGRPRHVYTGAPLREYVPVSKR
What are the official names of this protein?
Citrate synthase, chromosomal.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: AAS_YERPB
Sequence: MAYRLLRALFRGLFRVTIDGVTDQFKHEKLIITPNHVSFLDGALLALFLPIKPVFAVYTSITDTWYMRWLKPYVDFVALDPTNPMAIKHLVRMVEQGRPVVIFPEGRITVTGSLMKIYDGAAFVAAKSGAAVVPIRLDGPEFTHFGRLQGVLKTRWFPKISIHVLPATTIPMPQAPRSRERRVLAGEHLHTIMMAARMATVPRETLFEALLSAQTRYGRFKPCIEDVSFKEDSYQTLLKKTLGVSRILQRFTVPGEHVGMLLPNATITAAAIFGASLRGRIPALLNYTSGAKGLQSAIIAASLKTIVTSRQFLEKGKLTHLPEQVNEVNWVYLEDLKDTVTLTDKLWILFHLCFPRRAMLPQQADDSALILFTSGSEGNPKGVVHSHASLLANVEQIRTIADFTPRDRFMSSLPLFHAFGLTVGLFTPLMTGSRVFLYPSPLHYRVVPELVYDRNCTVLFGTSTFLGNYARFAHPYDFARVRYVVAGAEKLAESTKQIWQDKFGIRILEGYGVTECAPVVAINVPMAAKVNTVGRILPGMEARLINVPGIAQGGRLQLRGPNIMRGYLRVENPGVLEQPSAENAQGELDANWYDTGDIVTLDEQGFCAIRGRVKRFAKLAGEMVSLESVEQLAISLSPEGQHAAAAKTDSAKGEALVLFTTDSEITRERLIKAARENGVPELAVPRDIRVVKALPLLGSGKPDFVTLGKMAQDPEMSV
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAX_I60A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFISPKEAKKQLKKDLKSQGQCAGSPTKVSRRTSPALRILEPMWMDSNRTATLRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: KIFC2_HUMAN
Sequence: MYAFYSLLIYIFYSLFRRDGGAAAAAEPGDPAQRARKPRGRRRPDLPAPELWTELTGLAASSEPEDGSEGAAEGRAAAVSLEEALLRLAEFLSVQLGAEESCGGPADLGQSGEVPSLLTVTSQLLALLAWLRSPRGRQALLQGTQPAPRVRPPSPDGSTSQEESPSHFTAVPGEPLGDETQGQQPLQLEEDQRAWQRLEQLILGQLEELKQQLEQQEEELGRLRLGVGATDSEKRVQHLTLENEALKQSLSLMRDLLLHWGPGPPIRAPQEEAEALLELQGRLQEAQDTTEALRAQLGVQEVQLQGLQGALQQLQQETEQNCRRELQQMHGQLAGLRARMASLRQGCGDLRGLVSTFTQSCQGSLSEARGQVSWALGALSSGGPGTQLPEGQQGPPAGCPGRLPELKGNIRVLCRLRPGTSSSLVSVEPGPGGTVTTCYRGRHRRFRLDWVFPPDASQEEVFRELEPAVLSCLRGYSVCIFTYGQTGTGKTYSMEGPPEDPGIVPRALQSLFREMGAGRQHRVTLSMVEIYNEAVRDLLAPGPPERLAVRQGPEGQGGIQVAGLTHWDVPNLETLHQMLKLGRSNRATAATAMNQRSSRSHALVTLTLRAASPPRAPGTAGTLHLVDLAGSERARKAGAAGPPRGDPDGARRLREAQTINRSLLALGGVMAALRAHRPHVPFRDSQLTRLLQPALGPGTTAVLLLQVGAGAGQVCACRSPPTRARPPAPLARRSPRGRRISGRQSAPSSSPTEWVKWSWGQPGAAGSRAPPGRLLPSAPTLRSPGPPAPLRRPLAVLHAPVPTTARARLSRPQRACPSSPGSRPCPWGLRPGLCWQRR
What is the function of this protein?
May play a role in microtubule-dependent retrograde axonal transport.  May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites (By similarity).
What are the official names of this protein?
Kinesin-like protein KIFC2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SSRP_STRA3
Sequence: MVKGQGNVVAQNKKAHHDYTIVETIEAGIVLTGTEIKSVRAARITLKDGYAQIKNGEAWLINVHITPYDQGNIWNQDPDRTRKLLLKKREIEKISNELKGTGMTLVPLKVYLKDGFAKVLLGLAKGKHDYDKRESIKRREQNRDIARQLKNYNSR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ETFD_CAEEL
Sequence: MRISGVTLFRVSSQLRNVVNGQWTTTHYTVKDRSTDPRWKDVDLARESDVYDVVIVGGGPSGLSAAIRLRQLAEKAQKELRVCVVEKASVIGGHTLSGAVIETRALDELIPNWKELGAPVYQQVTSESIAILTESGRIPVPVLPGVPLANHGNYIVRLGKVVQWLGEQAEAAGVEVWPEIAASEVLYNEDGSVKGIATSDVGIGKDGAPKDGFARGMEFHAKCTIFAEGCRGHLSKQVLDKFDLRTHAMTYGIGLKELWEIDPAKHRPGYVEHTMGWPLNVDQYGGSFLYHIEDQGQPLVSVGFVVALDYANPNLNPYKEFQKYKTHPSISKQLEGGKRIGYGARALNEGGFQSIPKLHFPGGCLVGCSAGFLNVAKLKGTHNAMKSGMVAAESIFEDIQQKGEDVQTIDPATYDKNIRDTYVVKELKATRNIRPSFNTSLGYIGGLIYSGIFYVFGRGIEPWTLGHGKKDNEKLIPVKDAKEIDYPKPDGKLTFDLLTSVSLTGTNHTEDQPAHLTLKNDQVPLDVNLAVYGGPEARFCPAGVYEFVPSEADESKKRLQINAQNCIHCKTCDIKDPQQNINWVTPEGGGGPKYEGM
What is the function of this protein?
Accepts electrons from ETF and reduces ubiquinone.
What are the official names of this protein?
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial, ETF-QO, ETF-ubiquinone oxidoreductase, Electron-transferring-flavoprotein dehydrogenase, ETF dehydrogenase, Lethal protein 721.
What is the protein family that this protein belongs to?
Belongs to the ETF-QO/FixC family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: TIM9_YARLI
Sequence: MDQLNNREQQEFQQLVEQKQMKDFMRLYSSLVQRCFTDCVNDFTSKALSSREESCLEKCSEKFLKHSERVGQRFQEQNAALMQKR
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM9.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: RL24_HAEIE
Sequence: MAAKIRQNDEVIVLTGKDKGKRGKVTKVLPNGKVFVEGINIITKHEKPVPALGKAGGLVKKEAAIEASNVAIFNPKTNKADRVGFRFEDGKKVRFFKSNNEII
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TX115_LYCSI
Sequence: MMKVLVVVALLVTLISYSSGEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A15.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TIC22_PEA
Sequence: MESQGQWNPLLSFSRFINHHSNHLATRLEETKRLAGTLIQSHTRTKPAFAATLTPNHVAKSLAGTSVYTVSNSDNEFVLMSDAEGAKSIGLLCFRQEDAEAFLAQVRSRKKEFRGGAKVVPITLDQVYMLKVEGIAFRFLPDPVQIKNALELRAANRGSFDGVPVFQSDLLVVKKKNKRYCPVYFSKEDLEYELSKVSRSSKGVGVSQHIMVGSFEDVLKKMELSEKSSGWEDLVFIPPGKKHSQHMQEVIA
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  Imported into the intermembrane space via the Toc translocon.  May be involved in the import pathway used by proteins without a cleavable N-terminal pre-sequence.
What are the official names of this protein?
Protein TIC 22, chloroplastic, Translocon at the inner envelope membrane of chloroplasts 22, PsTIC22.
What is the protein family that this protein belongs to?
Belongs to the Tic22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast intermembrane space; Peripheral membrane protein.
Protein: BUD23_HUMAN
Sequence: MASRGRRPEHGGPPELFYDETEARKYVRNSRMIDIQTRMAGRALELLYLPENKPCYLLDIGCGTGLSGSYLSDEGHYWVGLDISPAMLDEAVDREIEGDLLLGDMGQGIPFKPGTFDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSEQLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNERFPLRMSRRGMVRKSRAWVLEKKERHRRQGREVRPDTQYTGRKRKPRF
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA (PubMed:25851604).  Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity (PubMed:25851604).  Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity (PubMed:25851604).  Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity (PubMed:24086612).  Locus-specific steroid receptor coactivator.  Potentiates transactivation by glucocorticoid (NR3C1), mineralocorticoid (NR3C2), androgen (AR) and progesterone (PGR) receptors (PubMed:24488492).  Required for the maintenance of open chromatin at the TSC22D3/GILZ locus to facilitate NR3C1 loading on the response elements (PubMed:24488492).  Required for maintenance of dimethylation on histone H3 'Lys-79' (H3K79me2), although direct histone methyltransferase activity is not observed in vitro (PubMed:24488492).
What are the official names of this protein?
Probable 18S rRNA (guanine-N(7))-methyltransferase, Bud site selection protein 23 homolog, Metastasis-related methyltransferase 1, Williams-Beuren syndrome chromosomal region 22 protein, rRNA methyltransferase and ribosome maturation factor.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm, perinuclear region. Cytoplasm. Note=Localized diffusely throughout the nucleus and the cytoplasm (PubMed:24488492). Localizes to a polarized perinuclear structure, overlapping partially with the Golgi and lysosomes (PubMed:25851604). Localization is not affected by glucocorticoid treatment (PubMed:24488492).
Protein: CSRA_BUCBP
Sequence: MLILTRRVGETLIIGDNISITVLGVKGNQVRIGVNAPKEISVHREEIYQRIQTEKKTQTQ
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_THEGJ
Sequence: MDYREFFSQFRHLSEKPGIGGKIKILPEDFVVIEDPLPQIFEGRKHAIFLLKKRNWDTMAVIKEIAKRAGISHRDIGFAGTKDRHAVTYQYISVPAGAKEKVESIQIRDVELRFVSYGRFIKLGHLLGNRFRIIIRDVEGSAFDRTKEIIRELREKGGFPNYFGYQRFGERRVVNHLIGKLLLQGEFDEAARLFLGYADGSMEGDEARRNFWETEDVDRALEEFPRFLRYERTLLYTYKKTGSWKKAFLSLPLPIMRIFIHAYQSYLFNLYLSRRIEELPLNEPLVGDIVVQVKGGIPYRDRTYRVTETNLNFVREKVKRGEAMVSGPLFGFAMRRAKGIPGELEEEILEGEGITLDAFKKLPKPMAEPGRRRELLIRPIGLTYGYLPETGMCFRFFLPKGVYATSVLREIMKDH
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: CHO2_CHAGB
Sequence: MSTSTAEPSGLDNVRHRARAASSISTDTAPEAVTEKEREARPNKTYGRTPDGTVFVVPETHDMVSQLLDPREPKNLSDVLVLAILALHIWAAYALPSSLKRPIFALIFLFWRASYNVGIGYLLTVQSNYKLMVIWAKRMQLFENPSTGKNPRPWLYQLLQNELEAKIPKDYKMAEAPLEYNTWLVFRRVVDLILMCDFVSYCLFAIVCAHKPVSEGFAIAAARWVIGIALVGFNLWVKLDAHRVVKDYAWYWGDFFYLIEQELTFDGVFEMAPHPMYSIGYAGYYGISMMAASYDVLFISILAHAAQFAFLAIVENPHIEKTYNPPPPRQRAESEVSSSEATAESFRKSTKTPSTPLPVHNMVGVHNFDPFRITDYTSVLLVGCFAALALVTPSTPIYQALFVVNAIVWRLWYSVGLGVILTKQSNEKMFTRHFLKFGETAAEAWRQWKGMYHLSMTLCYVSFLAACWKMYNYPADWGYGWVLLKHVVGISLVALQIWTATSIYESLGEFGWFYGDFFFDSTGKLTYKSIYRFLNNPERVIGTAGLWGMALITWSSPIFLIALIGHILTLGFISYVEKPHMQKIYGENLRQEAGLTKFIKRSLPEPVKGLQMSVDKVWEDSKHFFDDFVDVARTKLGAGSSTIARDTSALFNKYPARLTLSRISPDLAGYDPKHYSISMEGTPLVGADEKATGKESANARVSKAVKTKVFEYGAPIRVKWTAPANHSKKDWVGLYMVTDNRSREVTEVPTLGRWVPARPSQYDTTTDEGIVSWDQPAKSPCPEVDFVQGEMVFEGDKLWWTQGVFEFRYHHNSGHNVMAISEPFEVRLAKVDDEDTEVTGPREVEAALLPIVRNCLDRDPDIAPATVEERFGAHVERDSKYAKRVVYAIHHMFGVEFAPAVVPADGDVRKLAWRICSAKEVLAPYSMSQRLQSPSTPVRDKFPDSL
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: OBP2_HELVI
Sequence: MTSKSCLLLVAMVTLTTSVMGTAEVMSHVTAHFGKALEECREESGLSAEVLEEFQHFWREDFEVVHRELGCAIICMSNKFSLLQDDSRMHHVNMHDYVKSFPNGHVLSEKLVELIHNCEKKYDTMTDDCDRVVKVAACFKVDAKAAGIAPEVTMIEAVMEKY
What is the function of this protein?
Present in the aqueous fluid surrounding olfactory sensory dendrites and are thought to aid in the capture and transport of hydrophobic odorants into and through this fluid.
What are the official names of this protein?
General odorant-binding protein 2, GOBP 2.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.