PharMolix/UniProtQA huggingface dataset:
Protein: THIE_LISMO
Sequence: MRAELAVYFIAGTQDIVRGTLPSVLEEALKGGITCFQYREKGAGSLQTASERKEMALECQKLCAKYQVPFIINDDVALALEIGADGIHVGQTDEAIRQVIASCSGKMKIGLSVHSVSEAKEAERLGAVDYIGVGPIFPTISKADAEPVSGTAILEEIRRAGITIPIVGIGGINETNSAEVLTAGADGVSVISAITQSDDCHSVIKQLKNPGSPS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: METK_BIFLS
Sequence: MTEEHRLISAESVTEGHPDKVCDQISDAILDDLLVQDPSSHVAVETSAATGVFLVFGEVTSKGYCDVQSKVRETLRNIGYTSSEVGLDADSCGVVVAITEQSAEINQGVARLTGDQETAASREERYEAQGAGDQGVMFGYATDETPTLMPLPIYLAHRLAFRLTEVRKSGEVPHLRPDGKTQVTIEYDDNDKPVRLDTVLISTQHDPEVTQDWLAVELKKHVIDPVLDEVLGSKVPHDNYRQLVNPTGSFILGGPAADAGLTGRKIIVDTYGGAAHHGGGAFSGKDPSKVDRSAAYATRWVAKNIVAAGLAHKVEIQIAYAIGVADPVSVNVETFGTEQGVTRGQIAAAVRKVFDLRPAAIIDELDLKRPIYLKTAAYGHFGRTDVEFPWEKTDKVEELKAAIAAE
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQE_ACIAD
Sequence: MNIPVSLQSKPPLWLLAELTYRCPLQCAYCSNPLDYAAVKQELSTDEWKDVFRQARAMGSVQLGFSGGEPLLRQDLSELIKYAHELGFYTNLITSGIGLTEQKIAEFSEAGLDHIQISFQASDPALSEILSGSRKAFQQKQAMALAVKKHRYPMVLNFVIHRFNIEQIDQIIELSLELNADYVELATCQFYGWAKLNQAALLPTPEQISYAQARVQAYRQYIDQHHLKTKLLLVAPDYYQERPKKCIGGWGQIFITVSPDGTVLPCQSAKDLPLEFPTIQDQSLKTIWNEAFAFNAFRGTDWMQEPCRSCPDKDKDLGGCRCQAYMLTKNMYATDPVCSKSPVHHQIVEARLQTQCSKPDISDLKLRNPQNSKLFFKRASDADSLL
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: OBCAM_CHICK
Sequence: MYHPACWIVFTATTALLFIPGVPVRSGDATFPKAMDNVTVRQGESATLRCTVDDRVRRVAWLNRSTILYAGNDKWSIDNRVVILSNTKTQYSIKIHNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVPPQIVNISSDITVNEGSSVTLMCLAFGRPEPTVTWRHLSGKGQGFVSEDEYLEITGITREQSGEYECSAVNDVAVPDVRKVKVTVNYPPYISNAKNTGASVGQKGILQCEASAVPVAEFQWFKEDTRLANGLEGVRIESKGRLSTLTFFNVSEKDYGNYTCVATNKLGNTNASIILYGPGAVHDSGNAASRAAAGLCLWATLLARLLLDF
What is the function of this protein?
Inhibits neurite outgrowth.
What are the official names of this protein?
Opioid-binding protein/cell adhesion molecule homolog, Neurite inhibitor GP55-A, OBCAM protein gamma isoform.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: GMHA_CROS8
Sequence: MYQDLIRNELNEAAETLANFLKDEANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGYDHIFSRYVEAVGREGDVLLGISTSGNSGNVIKAIEAARAKGMKVITLTGKDGGKMAGTADVEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVKA
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAPC3_DROME
Sequence: MDLWHIFLERILVACRVSASVFANFGCGLYSSWKLICGDHDSASGLRAGLATPTQRGKATGDNGTTGTPARTIGKPQARIATAMSTATCARFCTPLSSGTAGSTSKLTTGNGSGNTMTSAYKIPSNNSTTANDSSNTETTFTFKLGRSNGRSSSNVASSESSDPLESDYSEEDPEQEQQRPDPATNSRSSSTATTTTTSSADHDNDVDEEDEEDDENEGEGNGRDADDATHDSSESIEEDDGNETDDEEDDDESEESSSVQTAKGVRKYHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKDWKPAKAVDQRDLQYFNDF
What is the function of this protein?
Does not have an essential role in development.
What are the official names of this protein?
cAMP-dependent protein kinase catalytic subunit 3, Protein kinase DC2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
Protein: NRDR_ALCBS
Sequence: MYCPFCSAQDTKVIDSRLVADGVQIRRRRECLSCTERFTTFETAELVMPRLVKTDGTRQPFDEAKLRAGMLRALEKRPVSMEDLEAAISRICHRLRATGERELPARELGEFVMEELQQLDDVAYVRFASVYRSFQDISEFSAEVDRLKKAGGKPGDKLGEPKES
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SGSM3_DANRE
Sequence: MSGSYTPAPGGPFSALTPSMWPQDILAKYCQKDPGTEVELQYDEFGFRIDSEDGVETRKWLCGDGAPQREDPQQRLRWQAHLEFTHNHTVGDLTWDKITPTLARSDRLRSLVLGGIPHSMRPQLWMRLSGALQKKRTSDISYREIVKNSSNDDTTAAKQIEKDLLRTMPTNACFNTLTSVGVPKLRRVLRGLAWLYPDIGYCQGTGMVVSCLLLFLEEEDALWMMCALIEDLLPPSYFSSTLLGVQTDQRVLRQLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIRILLRIWDLLFYEGSMVLFQVTLGMLKIKEDELVSSENSASIFNTLSDLPSQLEDGAAVLGEAVRLAGSLSQENLDTHRHKHLAYILAEQAQLNSNNSHSLNTNLNKVVRRQNMRRKSTLSSLLWGEDEVEALKAKNIKQTELVAALREAINRTAEHFHCLDPRNCSTDLTPDYSMESHQRDHENFLVVSRNRRRRAKALLDFERHDDDELGFRKNDIITIISQKDEHCWVGELNGLRGWFPAKFVEILDERSKEYSLAGDDTVTEAVNDLVRGSLCPALKAIFQHGLKKPSILGGPCHPWLFIEEAASKEVERDFNSVYSRLVLCKTYRLDEDGKVLTPEELLYRAVQSVNMSHDTAHVQMDVKFRSLICVGLNEQVLHLWLEVLCSSMSAVEKWYHPWSFLRSPGWVQIKCELRVLSKFAFSLSQDCELPTKKEEKEQRPLKEGVQDMLVKHHLFSWDIDG
What are the official names of this protein?
Small G protein signaling modulator 3, RUN and TBC1 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the small G protein signaling modulator family.
Protein: MDTH_ECO8A
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHRLMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLERDA
What is the function of this protein?
Confers resistance to norfloxacin and enoxacin.
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOH_VESOH
Sequence: MELWQTFVKMVHALVPWLDGTVAIILIIFIKAIALLIPLMLVVAYFTYAERKVIGYMQLRIGPNRVGPKGWLQPIADALKLMTKEIIFPTKANIYLFLLAPVLAIAPAIAVWAVIPFDESIYITNLDISLLYVLAIGSIGVYGIILAGWASNSKYPLLGALRSAALLVSYEIVIGFALVTVVMIAGSVNLNTIVQAQQGGIIYWYFIPLFPIMIIFFISSLVETNRAPFDVVEGESEIVGGTHVEYSGMTFAVFFLAEYANMILMAVLSVIMFFGGWHSPFEAIPYLESVFSWIPGMIWLLAKTTFFMFLYLWVRATFPRFRYDQIMHLSWKVFLPITIIWIFVVALMTQLQLSPWF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBC_SOYBN
Sequence: MKTLYSLRRFYHVETLFNGTLALTGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGIYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS8_MAGMM
Sequence: MSMNDPISDMLTRIRNAQMVGKDSVRMPASKMKKRIADILKEEGYIESISESVDEANHTTLELTLKYYQNKPVIEEIKRISTPGRRTYVGKAEIPSVYQGLGIAILSTSKGVISSRRALELGVGGELLCTVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GPI19_YEAST
Sequence: MYTKEYYWFSQYMIITSTLVLTIIWSILPSSLGEAAPKQFINTLLDIFPQRRWIITLESIMLMGMLCTYIGLLMYNEDTLTPPLDSLSTVTDAGGQLVIEDDPDVFVKKWAFKETSGIYDLSLMDACQLLYLYDNDHTST
What is the function of this protein?
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.  Involved in cell wall biosynthesis.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase subunit GPI19, GPI-GlcNAc transferase complex subunit GPI19, GPI-GnT subunit GPI19.
What is the protein family that this protein belongs to?
Belongs to the GPI19 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYL_ANOFW
Sequence: MSFNHREIEKKWQKYWEENKTFKTTEDDGKRKFYALDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTEKNINNFRRQIKSLGFSYDWDREVNTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVIDGKSERGGHPVIRKPMKQWMLRITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGANIHFQVDGHDETFTVFTTRPDTLFGATYAVLAPEHPLVEKITTPEQKEAVEAYLKQIQSKSDLERTDLAKEKTGVFTGAYAINPANGEKLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFNLPIKQVVAGGDISKEAYTGDGEHINSDFLNGLNKEEATKKMIEWLEANGKGEKKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLVLPKTDEIKPSGTGESPLANIEEWVSVVDPKTGKKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLEKWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLFNQGMILGENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVEENGELNPKIVDNPETDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEAYKAPILPKAYMEGFVKLLSPVCPHIAEELWEKLGYSNTIAYEAWPAYDEAKLVEDEVEIVIQVNGKVRAKLHVPADATKEQLEQLAMEDEKIKEQIEGKTVRKVIAVPGKLVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMR14_ARATH
Sequence: MAEEEPKKVTETVSEPTPTPEVPVEKPAAAADVAPQEKPVAPPPVLPSPAPAEEKQEDSKAIVPVVPKEVEEEKKEGSVNRDAVLARVETEKRMSLIKAWEEAEKCKVENKAEKKLSSIGSWENNKKAAVEAELKKMEEQLEKKKAEYVEQMKNKIAQIHKEAEEKRAMIEAKRGEEILKAEELAAKYRATGTAPKKLFGCM
What are the official names of this protein?
Remorin 1.4, AtREM1.4, Remorin group 1 member 4.
What is the protein family that this protein belongs to?
Belongs to the remorin family.
Protein: PVK1_BLACR
Sequence: GSSGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, BlaCr-PVK-1, PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PA2G5_RAT
Sequence: MKRLLTLAWFLACSVPAVPGGLLELKSMIEKVTGKNAVKNYGFYGCYCGWGGHGTPKDGTDWCCRMHDRCYGLLEEKHCAIRTQSYDYRFTQDLVICEHDSFCPVRLCACDRKLVYCLRRNLWSYNRLYQYYPNFLC
What is the function of this protein?
Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids.  Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity), preferentially releasing fatty acyl groups with a low degree of unsaturation such as oleoyl (C18:1) and linoleoyl (C18:2) groups (By similarity).  Hydrolyzes low-density lipoprotein (LDL) phospholipids releasing unsaturated fatty acids that drive macrophage polarization toward an M2 phenotype (By similarity).  May act in an autocrine and paracrine manner.  Contributes to lipid remodeling of cellular membranes at different subcellular locations and generation of lipid mediators involved in pathogen clearance.  Cleaves sn-2 fatty acyl chains of cardiolipin, a major component of the inner membrane of mitochondria and bacterial membranes.  Promotes phagocytosis of bacteria in macrophages through production of lysophosphatidylethanolamines.  Displays bactericidal activity against Gram-positive bacteria by directly hydrolyzing phospholipids of the bacterial membrane (By similarity).  Promotes phagocytosis and killing of ingested fungi likely through controlling phagosome-lysosome fusion and phagosome maturation (By similarity).  Plays a role in biosynthesis of cysteinyl leukotrienes (CysLTs) in myeloid cells.  In eosinophils, triggers perinuclear arachidonate release and LTC4 synthesis in a PLA2G4A-independent way.  In neutrophils, amplifies CysLTs biosynthesis initiated by PLA2G4A (By similarity).  Promotes immune complex clearance in macrophages via stimulating synthesis of CysLTs, which act through CYSLTR1 to trigger phagocytosis.  May regulate antigen processing in antigen-presenting cells.  In pulmonary macrophages regulates IL33 production required for activation of group 2 innate lymphoid cells (By similarity).  May play a role in the biosynthesis of N-acyl ethanolamines that regulate energy metabolism.  Hydrolyzes N-acyl phosphatidylethanolamines to N-acyl lysophosphatidylethanolamines, which are further cleaved by a lysophospholipase D to release N-acyl ethanolamines (By similarity).
What are the official names of this protein?
Phospholipase A2 group V, PLA2-10, Phosphatidylcholine 2-acylhydrolase 5.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Cytoplasmic vesicle, phagosome. Recycling endosome. Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network.
Protein: CRCB_BACTN
Sequence: MLKTLLFIGMGSFTGGVLRYLISRYVQNFLTPSFPLGTLLVNVLGCFAIGLFYGLFERGNLMNPNLRMFLTVGFCGGFTTFSTFMNENFQLIKDDNFFYLSLYVGLSLFVGFIMLYLGYSLVKQ
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: C7103_ARATH
Sequence: MVSSVSLFASLTPYLVSALLLFLLLEQLFYRLKKRNLPGPLFVFPIIGNVVALIRDPTSFWDKQSAMADTSVGLSVNYLIGKFIIYIKDAELSNKVFSNIRPDAFQLVGHPFGKKLFGDHSLIFMFGENHKSVRRQVAPNFTRKPLSAYSSLQQIVILRHLRQWEESFSSGSRPVSMRQLIRELNLETSQTVFVGPYLDKEVKNTIRDDYNVFNPGTMALPIDLPGFTFGEARRAVSRLVNTMSLCVRKSKEKMAAGENPTCLVDFWTHSIVAESPPPPHSKDEEISCVLVDFLFASQDASTSSLLWAVVLLESEPEVLRRVREDVARFWSPESKESITADQLAEMKYIRAVAREVLRYRPPASMVPHVAVSDFRLTESYTIPKGTIVFPSLFDASFQGFTEPDRFDPDRFSETRQEDEVFKRNFLTFGIGSHQCVGQRYALNHLVLFIAMFSSMFDFKRVRSDGCDEIVHIPTMSPKDGCTVFLSSRLVTSP
What is the function of this protein?
Required to form the C-22 double bond in the sterol side chain.  Possesses in vitro C-22 desaturase activity toward beta-sitosterol and produces stigmasterol.
What are the official names of this protein?
Cytochrome P450 710A3, C-22 sterol desaturase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y642_METMP
Sequence: MIVVGIDHGTSGITACVMENKTVKSVFKMKRTEINEKSFLKELEKQVNLNDIDLIGVCYSMGDGIDKITDIKRVENRGVINLEGIGKKIGGGTKVYDEIKSSNIPAIVIPGLHNGVKSMDKRFNALFSHIASPEKISICYNAYKTFGFENFILSDISSNTVTLLIKDGKIFGGFDACVGAVGILHGPIDLELIRNIDADKITANEAFSKAGVVKVTDSYKGVEDTKFEIMNNYDKDEKCKLAVDSLVLSVSMEINSLMFLTPDKNVILAGSIGTWENPNVSKMIKENIDGNVLVLNRESGAIGSAMIAEDILNGKKEILGIPVDF
What are the official names of this protein?
UPF0285 protein MMP0642.
What is the protein family that this protein belongs to?
Belongs to the UPF0285 family.
Protein: FPG_PHOLL
Sequence: MPELPEVETSRRGIEPHLVGNVIQYAVVRNGRLRWPVAEEIMKLSDQLVLSIQRRAKYLLIELANGWIIVHLGMSGSLRILPEERPAEKHDHVDLVMADGKVLRYTDPRRFGAWLWSDDLERCSVLAHLGPEPLSDDFNGFYLYTRSSNKKTLIKPWLMDNKLVVGVGNIYANEALFTAHIQPDRPAQTLTEREAHLLAETIKKVLQRSIERGGTTLRDFLQSDGKPGYFAQELFVYGRAGEPCRICGEQIESIKLGQRSTFFCRHCQY
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RECR_STAES
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAQRLAFHTLDMKEDDVVKFAKALVDVKRELTYCSVCGHITENDPCYICEDKQRDRSVICVVEDDKDVIAMEKMREYKGLYHVLHGSISPMDGIGPEDINIPALVERLKNDEVKELILAMNPNLEGESTAMYISRLVKPIGIKVTRLAQGLSVGGDLEYADEVTLSKAIAGRTEM
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HSSR_STAHJ
Sequence: MVKCLIVDDDYKILHYVSQHLEAAQIQTVTQASGESAIAYLANNKVDIAVVDIMMTGMDGFELCQLLKNDYDLPVIMLTARDALSDKERAFVSGTDDYVTKPFEVKELLFRIQAVLRRYQINSQDIIKLGNVTLIQEYMELSVDSKNVNLPTKEFQLLFLLCGQPKHIFTRDTLIERIWGFDYEGDERTIDVHIKRLRHRLNQLKATIEIQTVRGQGYRVITHV
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme response regulator HssR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_PITPI
Sequence: MVHLTGEEKAAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFESFGDLSSPDAVMNNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVDPENFRLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YH182_YEAST
Sequence: MWPSFFRTTWHQRWTVTGTFLTTGDTRTNEKNTLLLQFFVTSIRIWEVRVTTIDDNITLFQKWDDLVDQSVNWSTSFNQKHDLSRSLQFGDEIFNGSSTDDRFALSFIGQEMVDLGLSSVVSTNSETVVSSVQDQILTHDGQTNQTEISRHFIVVFV
What are the official names of this protein?
Putative uncharacterized protein YHR182C-A.
Protein: MVP_TRVPP
Sequence: MEDKSLVTLKKKTFEVSKFSNLGAIELFVDGRRKRPKYFHRRRETVLNHVGGKKSEHKLDVFDQRDYKMIKSYAFLKIVGVQLVVTSHLPADTPGFIQIDLLDSRLTEKRKRGKTIQRFKARACDNCSVAQYKVEYSISTQENVLDVWKVGCISEGVPVCDGTYPFSIEVSLIWVATDSTRRLNVEELNSSDYIEGDFTDQEVFGEFMSLKQVEMKTIEAKYDGPYRPATTRPKSLLSSEDVKRASNKKNSS
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Displays RNA-binding activity.
What are the official names of this protein?
Movement protein, 29 kDa protein, Cell-to-cell transport protein, P1a.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
Protein: YLXQ_BACSU
Sequence: MSGMEWFPLLGLANRARKVVSGEDLVIKEIRNARAKLVLLTEDASSNTAKKVTDKCNYYKVPYKKVESRAVLGRSIGKEARVVVAVTDQGFANKLISLLD
What is the function of this protein?
RNA-binding protein that recognizes the K-turn motif present in ribosomal RNA, but also in box C/D and box C'/D' sRNAs.
What are the official names of this protein?
Probable ribosomal protein YlxQ.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: RRF_LACLS
Sequence: MANEIVTTAQERMKHSLASLQRDLGHLRAGRANASLLDRVQVVYYGAPTPLNQLASITIPEARVLMVTPFDKSILKDIEKSLYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKYIESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENEIQKVTDDAVKEADRLASVKEKELLDI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5374_PARP8
Sequence: MIVSIPDVLSPAEAAAMRAQLEASDAWVDGRATAGYQGAPVKRNQQIGEGSPIALEMGDRIVASLERHPLFISAALPNKVYPPLFNRYEGGMHFGSHVDGAIRLVPGSGARVRTDVSVTLFLTPPDEYDGGELLIEDTFGVQEVKLPAGHAIVYPGTSLHQVRPVTRGARVASFFWVQSLVRDDTQRAMLFDLDGAIQRLNASNGDEAARRTLVGCYHNLLRMWSDT
What are the official names of this protein?
PKHD-type hydroxylase Bphy_5374.
Protein: DKSA_SALTI
Sequence: MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLSHFKRILEAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG
What is the function of this protein?
Transcription factor that acts by binding directly to the RNA polymerase (RNAP).  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.  Also required for regulation of fis expression.
What are the official names of this protein?
RNA polymerase-binding transcription factor DksA.
What is the protein family that this protein belongs to?
Belongs to the DksA family.
What are the subcellular locations of this protein?
Cytoplasm.