PharMolix/UniProtQA huggingface dataset:
Protein: TBC31_MOUSE
Sequence: MQSTDLGNKESGKIWHRKPSPATHDGIIVNIVHSTSEYHPKVLRFLNVAFDGSGDSFIAGDHQGNIYVFDLHGNRFNLVQRTAQACTALAFNLRRKSEFLVALADYSIKCFDTVTKELVSWMRGHESSVCSISVHASGRYAITTSSDTAQLWDLDTFQRKRKLNIRQSVGIQKVFFLPLSNTILSCFKDNSIFAWECDTLFCKYQLPGPPEGSNILYKVFAVTRDGRILAAGGKSNHLHLWCLEATGLFRIIQMPAKVRAVRHLEFLPDSFDAGSNQVLGVLSQDGIMRFVNIQTCKLLFEIGTVEEGISSSVISPHGRYIASIMENGSLNVYSVQALTQEINKPPPPLVKVIEDLPSNTVSSSNLKMKIMPGRVQRPARCKESKIPTRVLKQDLTGDLENKENELSEGLNKKRLQILLKGYGEYPTKYRMFIWRSLLQLPENHTAFSSLVDKGTHAAYLSLQKKYPIKSRKLLRVLQRTLSALAHWSAIFSDTPYLPLLAFPFVKLFQNNQLICFEVVATLIINWCQHWFEYFPNPPINILSMIENVLAFHDKELLQHFIDRDITSQVYAWPLLETLFSEVLTREEWLRLFDNIFSNHPSFLLMTVVAYSTCSRAPLLNCTLKNDFEYFFHHRNNLDINVVIREVYHLMETTPADIHPNSMLDAFVALTKGQYPIFNQYPKFIVDYQTREWERIRNDELDFLRERQTVENMQAEVDEQRAKDEAWYQKQELLRRAEETRREILLQEEEKMAQQRQRLAAVKRELEIKEIHLQDAARRRLLKLQQDQREMELRRLEDEIERKVQMRDQEIAATAKDLEIRQLELEAQKRLYEKDLTTSQEAVAKEIREDTDAHRRKAALEEHMFQKLLENSQMGGRRAQRWKEAEEKEFHLQSAKKASALSDASRKWFLRQETSAALEHEEMPWLQRQYMDSAYLPQTSRLHDVSDMDPSTHIFSRNYPTEWNHMEHDLLKNVRDLRRRLTARARNSCRHPHLLVT
What is the function of this protein?
Molecular adapter which is involved in cilium biogenesis.  Part of a functional complex including OFD1 a centriolar protein involved in cilium assembly.  Could regulate the cAMP-dependent phosphorylation of OFD1, and its subsequent ubiquitination by PJA2 which ultimately leads to its proteasomal degradation.
What are the official names of this protein?
TBC1 domain family member 31, Protein 4-B-3, WD repeat-containing protein 67.
Protein: TIPT_DROME
Sequence: MMLHEAVMLEIYRQALSASELTSPRCQSRDSNTSAGAGAGMADVRCPSNESHCSANDRLTPAATPTLTPTEATISPNSVGLPLTATLPPAAAVALLPPQSAAMAAYLAAAQQNHLLLTNPLAAAASLVQHATQQAVVEGEVESPALDFSRKRPKSHGDDDQEEDQEQDQEQEQEQEPDHDVQCDNGPLDLSVSTGKRQESVSPPARKIPRSISADYKSPLPPGSWMPPINPYLAAVAAKTGGLGYSKLAPSEASKALEKMTEMSRLETSPTAARSLGATSSVGAGVPAGASSNSGGRHSAWQSHWLNKGADTAKDVFKCVWCKQSFSTLANLTAHMKETQHCGVQIPSPLPTGGVGTPSAPPPTRLATSASNSACSSSSSSTSSSSNSSKSELNMLIKETMPLPRKLVRGQDVWLGKGAEQTRQILKCMWCGQSFRSLAEMTSHMQETQHYTNIISQEQIISWKSGDERERPTNTGVPSTSTAAPSSPSCTAPSVSAVLTCKVCDQAFGSLKELSTHMAQKSHYKESPAPSASPPAAGTGNPKRGRQNRNEKRKKSLPVRKLLELERSGSNSSLDSALKPLRDFAAATKITCEKCGSKIETALFVEHIRKCLGESIPIPPRRSNAGVDRLPSPSLGLGAEKPPSVLNALEQLIEKSFESRTSRTMTHGGYSEAGTPLGASILKRLGIEDSSDYTKPLMDAQAMHLLRSSFASRDRSASESSSASRVESSYTPDRQQATPHKSPDTPAPPPPPPPTIKAEPLEAEPLVGCDREGCSPRQQIQVKKEFSMEACRESPRSVSKSPAPQTERSPPDNGSLLALNSMFDQLSGVENSGNNNSGHCFNNNNSCSSVSAQKPKAHPLAALQKLCETTDPPSTGLRSASSAGSSTASATLPSANGNDLVAFSWACNEAVLSASNGGSAGDSSIIKCSYCDTPFASKGAYRHHLSKVHFVKDAGEDSPRLKSPAVQSPRSMPLASPRRSASRSPATGSQQPPPSPTISPYDESPQSKFLKYTELAKQLSSKNA
What is the function of this protein?
Tiptop (tio) and teashirt (tsh) have, on the whole, common activities.  Tio and tsh repress each other's expression and tsh has a crucial role for trunk patterning that is in part masked by ectopic expression of tiptop.  Both genes share a common activity required for the activation of Ser and svb and the maintenance of en and wg.
What are the official names of this protein?
Protein tiptop.
What is the protein family that this protein belongs to?
Belongs to the teashirt C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WASC3_BOVIN
Sequence: MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILDAKLSSIPGLDDVTFEVSPVNVTRITNGTHSEATSEQSQQNSLQDSGPQESEVTPENILTVAKDPRYARYHKMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGEGEKNTEESSDSESSFSD
What is the function of this protein?
Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
What are the official names of this protein?
WASH complex subunit 3, Coiled-coil domain-containing protein 53.
What is the protein family that this protein belongs to?
Belongs to the CCDC53 family.
What are the subcellular locations of this protein?
Early endosome.
Protein: CDKL3_HUMAN
Sequence: MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHENLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELKAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRVIKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKENPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQEDPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGMEVKQIKMLKRESKKTESSKIPTLLNVDQNQEKQEGGDGHCEGKNLKRNRFFFW
What are the official names of this protein?
Cyclin-dependent kinase-like 3, Serine/threonine-protein kinase NKIAMRE.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYF_EUGGR
Sequence: MASLQTPVMVGTVVGCVAGVVGFLAMSSNAATSLSVAPASTSTQIIANPSVIAPQYQGSVTSEDVAMEASQTDFAEVAEISSPVQVQSWSMIFSAMLAVPLAAAAMFFMKKSTTEERRPLVSIDDLLSVGKKAVVASAVVGAAAGSANAYPIFAQQAYGNPREATGRIVCANCHLASKPTEIEVPQAVLPDQVFEAVTKVPFSGPSGFFNVVDPSTVVGSVTFAGTQPVGFIQESGVPVSQALVDIATPGTPDTVFKATIKVPYDESLKQVAGNGRAAPLNVGAVLILPEGFRLAPPERIPEKMKEEINGLQFIQYSKDTPNILVVGPVPGKKYAEMTVALLSPDPRVDKKAEFGTLPIYVGGNRGRGQLYPTGEKSNNNIYNVEHSGKIADIQLNEKKRIYTVAVQQKDGEIINEDLPAGAELIVKVGDVVEAGQAISTNPNVGGFGQAESEIVLQNPGRVQAFLFFSFTVLATQTLLVVKKKQYEQVQLSEMNF
What is the function of this protein?
Translocates protons across the thylakoid membrane and transfers electrons from photosystem II to photosystem I.  It receives electrons from the Rieske iron-sulfur protein and passes them to plastocyanin.
What are the official names of this protein?
Cytochrome f, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: VEMP_BCHK3
Sequence: MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCCNIVNVSLVKPTVYVYSRVKNLNSSEGVPDLLV
What is the function of this protein?
Plays a central role in virus morphogenesis and assembly.  Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport.  Also plays a role in the induction of apoptosis.
What are the official names of this protein?
Envelope small membrane protein, E protein, sM protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses E protein family.
What are the subcellular locations of this protein?
Host Golgi apparatus membrane; Single-pass type III membrane protein. Note=The cytoplasmic tail functions as a Golgi complex-targeting signal.
Protein: IF11_BURPS
Sequence: MAKEELIELDGIVDEVLPDSRYRVTLDNGVVVGAYASGQMRRHRIRILAGDRVTLELSVYDLTKGRINFRHKDERRSDAAPRASARRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR1_LACLA
Sequence: MTTLLIILAHPHTDDFSWSLATVEEFKKSYQESHPLDKIIIRDLFSEKVPALDNETFAAWKRNKYAPDTLSAEDKNLLHRHEEYLEEFLSADKYVFVNPMYNGFVTAELKQYIDVIAVPRKLFRYTENGPIGLLEGKKSLHIQSAGGFYHNEQDPTHMANDLGAAYIDQTMKMVGLTDENRQQLFVEGYARYPERADELKEKAFTSAENFGKAF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: IFNB2_BOVIN
Sequence: MTHRCLLQMVLLLCFSTTALSRSYSLLRFQQRRSLALCQKLLRQLPSTPQHCLEARMDFQMPEEMKQAQQFQKEDAILVIYEMLQQIFNILTRDFSSTGWSETIIEDLLEELYEQMNHLEPIQKEIMQKQNSTMGDTTVLHLRKYYFNLVQYLKSKEYNRCAWTVVRVQILRNFSFLTRLTGYLRE
What is the function of this protein?
Has antiviral, antibacterial and anticancer activities.
What are the official names of this protein?
Interferon beta-2.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_VALMU
Sequence: MSPQTETKAGVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEERGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEDQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLECTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASRGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAAEGGEIIREACKWSP
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUSB_XANOP
Sequence: MSKPGGHPRHGRRDGIDPVLRSRARRRALQAVYAWQISGGFAKQVIAQFAHEQAHEVADLAYFENLVEGVLTNRAELDTALTPYLDRGVEEVDAIERAVLRLAAYELLYRQDVPYRVVINEAIETAKRFGSEHGHTYVNGVLDRAAVEWRKVESGA
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: RL11_POLSJ
Sequence: MAKKIVGFVKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAQTQGVEPGLPLPVVITAYADKSFTFIIKTPPAVTLIKKAIKLDKGSATPHTAKVGKITRAQLEEIAKTKMKDMTAADLDAAVRTIAGSARSMGVTVEGVV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: IXTPA_ANADE
Sequence: MDLLFGSTNPGKLRELRRLVAGLPLRVVSPDDLGRPLPVVVEDGATFQANAEKKAVAWARWSGLHAVADDSGLCVDALGGAPGVHSARWSDLEPEGPASPVCELAGVAELELGPVAGRAARDERNNDKLLAALSGLPDPRRGARYEAVLALARPDGTLVGTVTGTCPGRIGHARRGDGGFGYDPLFVPAAELAAGEGARVRTMAELSSDEKDALSHRGEAFRKLLPMLAALARGA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: RL14_HAEI8
Sequence: MIQEQTMLDVADNSGARSVMCIKVLGGSHRRYAAIGDIIKITVKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNTEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y2584_MYCLB
Sequence: MDTRRRVWPVAIITPHVTDVFAQRATLTRSLQLLSEFRYEQPYPARFYRALAADTVAMVGDLWLSTHGAPPVGRILLDVGSGSGYFAAAFADAGVRYIGVEPDPREMHAAGPALVPKAGAFVRASGMALPFADDAVDICLSSNVAEHVPQPWQLGNEMLRVTKPGGLVVLSYTIWLGPFGGHEMGLTHYLGGARAATRYVRKHGHRAKNDYGSSLFPVSAADGLNWAASTGVAVAAFPRYHPRWAWWLTSVPVLREFVVSNLVLVLRPR
What are the official names of this protein?
Uncharacterized methyltransferase MLBr02584.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: LIPA_PSYA2
Sequence: MTNAVQTHMPAARAKPKKAIQGEKLRGYDKVARIPIKIIPTVEAKKKPDWIRVKLSSPAEVARIKSTLREQKLYTVCEEAACPNLPQCFADGTATFMIMGDICTRRCPFCDVGHGRPNELDKDEPRHTAETIQGLGLKYAVITSVDRDDLKDGGAAHFVEVLNESRALSPNCLIEILVPDFRGRMDIALDLLTETAPDVFNHNIETVPRLYKAFRPGSDYQHSLDLLKIYKERRPDIATKCGFMVGLGETEEEIYKLLDDLKAHNVDMITVGQYLQPSKDHAPVDRYVHPDEFQRYMDYGKKIGFFNIWAGPMVRSSYFADRQYYGEDCPAPIRSKKALAAEGKLGC
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOL_PYRFU
Sequence: MILDVDYITEEGKPVIRLFKKENGKFKIEHDRTFRPYIYALLRDDSKIEEVKKITGERHGKIVRIVDVEKVEKKFLGKPITVWKLYLEHPQDVPTIREKVREHPAVVDIFEYDIPFAKRYLIDKGLIPMEGEEELKILAFDIETLYHEGEEFGKGPIIMISYADENEAKVITWKNIDLPYVEVVSSEREMIKRFLRIIREKDPDIIVTYNGDSFDFPYLAKRAEKLGIKLTIGRDGSEPKMQRIGDMTAVEVKGRIHFDLYHVITRTINLPTYTLEAVYEAIFGKPKEKVYADEIAKAWESGENLERVAKYSMEDAKATYELGKEFLPMEIQLSRLVGQPLWDVSRSSTGNLVEWFLLRKAYERNEVAPNKPSEEEYQRRLRESYTGGFVKEPEKGLWENIVYLDFRALYPSIIITHNVSPDTLNLEGCKNYDIAPQVGHKFCKDIPGFIPSLLGHLLEERQKIKTKMKETQDPIEKILLDYRQKAIKLLANSFYGYYGYAKARWYCKECAESVTAWGRKYIELVWKELEEKFGFKVLYIDTDGLYATIPGGESEEIKKKALEFVKYINSKLPGLLELEYEGFYKRGFFVTKKRYAVIDEEGKVITRGLEIVRRDWSEIAKETQARVLETILKHGDVEEAVRIVKEVIQKLANYEIPPEKLAIYEQITRPLHEYKAIGPHVAVAKKLAAKGVKIKPGMVIGYIVLRGDGPISNRAILAEEYDPKKHKYDAEYYIENQVLPAVLRILEGFGYRKEDLRYQKTRQVGLTSWLNIKKS
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase, DNA polymerase B, Pfu polymerase, Pol I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: IAC1_BOVIN
Sequence: EIYFEPDFGFPPDCKVYTEACTREYNPICDSAAKTYSNECTFCNEKMNNDADIHFNHFGECEY
What is the function of this protein?
Strong inhibitor of acrosin.
What are the official names of this protein?
Acrosin inhibitor 1, Acrosin inhibitor I, BUSI-I.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPA_YERE8
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKVGQTLLLHHVPNILSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNTYWKVRQAVETAKETLYTFDQLKSNKTEPRRPLRKMVFNVPTRRELTSGERAIQHGLAVASGIKAAKDLGNMPPNICNAAYLASQARQLADAFSTNIITRVIGEQQMKELGMHSYLAVGHGSQNESLMSVIEYKGNPNPDAKPIVLVGKGLTFDSGGISIKPAEGMDEMKYDMCGAATVYGVMRVVAELQLPLNVIGVLAGCENMPGGRAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDALTYVERFEPEVVIDIATLTGACVVALGHHITGLMSNHNPLAHELIGASEQAGDRAWRLPLGDEFYEQLDSNFADMANIGGRAGGAITAGCFLSRFTRKYSWAHLDIAGTAWRSGKNKGATGRPVALLSQFLLNRAGLNGDD
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAS_PHOLL
Sequence: MLFKFLRLVFRLMFRLTVEGDIKQFNHPKCLITPNHVSFLDGVLLTLFLPVKPVFAVYSNIANRGFMKLVSRYVEIVPLDPINPMAVRILVKEIEKGRPIVVFPEGRITVTGSLMKIYDGAAFIAAISEAVVVPVRFEGLERTLFSRLKGIFKLHLFPKVTMKILPATQLLMPNASSSEQRRRLAGERLHEIMMNARMATRPQETIFESLLVARKQFGRFKPCIEDVSFKEDSYNSLLKKVLAASRILQRFTCQGERIGFLLPNATIMVAAIFGASLRGRIPALLNYTTDSHGLKNALAVASIKTIVTSRQFLKKERLTHLSEQVTEVNWVYLEDLESTVTLLDKLWILWHLFFPKQAMVAQKPDDDALVLFTSGSDAVSKGVVHSHASLLANVEQIKTITDFNPLDRFMSSLPLFHAFGLTVGLFTPLLSGSRIFLYPNPLHYRVVPELVYECNCTVLLGTSSFLENYAYSAHPYDFARLRCVIAGIEKLAENTKQIWQDKFGIRILEGYGMTECAPVIALNVPMMAKVGTVGRILPAMEFRLIPIAGIKQGGRLQLRGPNMMKGYLRMEDPNHLEPPAVKDEHGNIQFDWLDTGDIVSIDEQGFCTILGRGKRFAKQGELDGGKADFVTLCKIAEAE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROE_SACS2
Sequence: MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFRTLGINAVYLVFDLDEMKFKRSISGILEIAEGLNVTIPYKDEVMKYLDNTDTHSTRIQAVNTIYKKSGYNTDYLAIKNLVRKKIKNVSGYECYIYGAGGAAKAAAFALSELGCSSISIVNRTKSRAYELAELLNKNGYNASIKENCNITNNILIVNSTPNSSVVPEDCVKKSDLVIEFVYRPVETELIKNAKKYGIQYINGLEILVNQAVEAEKIWFNKSVADEKIIEYLYARELVW
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: HHEX_HUMAN
Sequence: MQYPHPGPAAGAVGVPLYAPTPLLQPAHPTPFYIEDILGRGPAAPTPAPTLPSPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTIELEKKFETQKYLSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSNKKEELESLDSSCDQRQDLPSEQNKGASLDSSQCSPSPASQEDLESEISEDSDQEVDIEGDKSYFNAG
What is the function of this protein?
Recognizes the DNA sequence 5'-ATTAA-3' (By similarity).  Transcriptional repressor (By similarity).  Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982).  Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity).  May play a role in hematopoietic differentiation (PubMed:8096636).
What are the official names of this protein?
Hematopoietically-expressed homeobox protein HHEX, Homeobox protein HEX, Homeobox protein PRH.
What are the subcellular locations of this protein?
Nucleus.
Protein: GDL30_ARATH
Sequence: MNCLMFFKMLLAFSFISLFYVGNAQQSYGNSTVSALFAFGDSILDTGNNNLLLSVSKVNFYPYGRDFIGGRATGRFGNGRVFSDIIAEGLGLKNLLPAYRDPYLWNNDLTTGVCFASGGSGLDPITARTTGSIWVSDQVTDFQNYITRLNGVVGNQEQANAVISNAVYLISAGNNDIAITYFTTGARRLQYTLPAYNDQLVSWTRDLIKSLYDMGARKFAVMGTLPLGCLPGARALTRACELFVNQGAAMFNQQLSADIDNLGATFPGAKFVYVDMYNPLLGLIINPQASGFIDVADACCCTPTHLIPCLDASRYVFWDVAHPTQKSYETIAPQIIENIKAKLA
What are the official names of this protein?
GDSL esterase/lipase At1g73610, Extracellular lipase At1g73610.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: LAC1_THACU
Sequence: MARTTFLVSVSLFVSAVLARTVEYGLKISDGEIAPDGVKRNATLVNGGYPGPLIFANKGDTLKVKVQNKLTNPEMYRTTSIHWHGLLQHRNADDDGPSFVTQCPIVPRESYTYTIPLDDQTGTYWYHSHLSSQYVDGLRGPLVIYDPKDPHRRLYDVDDEKTVLIIGDWYHESSKAILASGNITRQRPVSATINGKGRFDPDNTPANPDTLYTLKVKRGKRYRLRVINSSEIASFRFSVEGHKVTVIAADGVSTKPYQVDAFDILAGQRIDCVVEANQEPDTYWINAPLTNVPNKTAQALLVYEEDRRPYHPPKGPYRKWSVSEAIIKYWNHKHKHGRGLLSGHGGLKARMIEGSHHLHSRSVVKRQNETTTVVMDESKLVPLEYPGAACGSKPADLVLDLTFGLNFATGHWMINGIPYESPKIPTLLKILTDEDGVTESDFTKEEHTVILPKNKCIEFNIKGNSGIPITHPVHLHGHTWDVVQFGNNPPNYVNPPRRDVVGSTDAGVRIQFKTDNPGPWFLHCHIDWHLEEGFAMVFAEAPEAVKGGPKSVAVDSQWEGLCGKYDNWLKSNPGQL
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-1, Benzenediol:oxygen oxidoreductase 1, Diphenol oxidase 1, Urishiol oxidase 1.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: DSS4_YEAST
Sequence: MSKATCSFEGCHSAVITINDDNIINLPEQVHSEFKLLENRTMRDATPSESNFLVVPDVWDFDNVGVSREIPSSILGDLSDKSDFVFEYGNSSWKIKKCLKYLICADCDKGPIGIICKVQDQTKNEERVLHLLSLRSLQIMGRN
What is the function of this protein?
Guanine-nucleotide-releasing protein that acts on SEC4.  Might play a general role in vesicular transport.
What are the official names of this protein?
Protein DSS4.
What is the protein family that this protein belongs to?
Belongs to the DSS4/MSS4 family.
Protein: TRPA_BACSU
Sequence: MFKLDLQPSEKLFIPFITAGDPVPEVSIELAKSLQKAGATALELGVAYSDPLADGPVIQRASKRALDQGMNIVKAIELGGEMKKNGVNIPIILFTYYNPVLQLNKEYFFALLRENHIDGLLVPDLPLEESNSLQEECKSHEVTYISLVAPTSESRLKTIIEQAEGFVYCVSSLGVTGVRNEFNSSVYPFIRTVKNLSTVPVAVGFGISNREQVIKMNEISDGVVVGSALVRKIEELKDRLISAETRNQALQEFEDYAMAFSGLYSLK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MURG_HAHCH
Sequence: MSGKTFLVMAGGTGGHVYPALASALALREQGANVVWLGARGGMEERIIGRTDIPMRLITIGGLRGKGVAALLMAPVNLVRALWQAFSVFRKEKPDCVLGMGGFASGPGGIVACLTGTPLVIHEQNAIAGMTNRWLARGARYVLEAFPQTFAQAQSVVTVGNPVRDELAALPSPQERGIGARKPTLLILGGSRGALALNEAAPKAIAALPETLRPRVVHQAGEGKDQTCRELYASLGVEAEVYDFLQDMASVYANADLALCRAGALTLAELCTVGLGALLAPYPHAVDDHQTANARHLEQAGAAKIFQQDNLTVERLAETLTSLLGQPQKLLDMANAARTLAKPEATREVVKYCWEACAND
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARGR_CLOBL
Sequence: MKVSRHAKILEIINSKDIDTQEELAEELKKMGMNVTQATVSRDIKELKLIKVLGNTGKYKYATINHTESYMSDKLINIFAQTVINVENIDKLIIIKTISGSAPAAAEAIDTLGFDGVAGTIAGDNTIFVMARTNEKAQEITMKLKKIITA
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.