PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_MYCS5
Sequence: MLEKNKGKIIQILGPVVDVRFTTGKLPKLLNALRVELPTKEVFTFEVAQHIGDDTVRCISMVSTNGLRRGLTVEDTGKAIMVPVGKQVLGRMFDVLGNPIDELPLEEGGEKSSIHGPIPTYEQQKTTSEILETGIKVIDLLIPYAKGGKIGLFGGAGVGKTVLVQELINNIATQHNGLSVFTGVGERTREGNDLYYEMKAAGVLDKTALVFGQMNEPPGARMRVALTGLTMAEYFRDKQNQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGALQERITSTRSGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLDRNVAALGIYPAIDPLESSSRLLDPLVVGQEHYKVAQDVINILQRFKELQDIIAILGMGELSEEDKKIVARARKIRNFLSQPFTVAEKFSGIKGSYVKLSDTIRSFKEILNGNLDDYPEDIFRYAGSIDDVIARYKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: OMT3B_PAPSO
Sequence: MEVVSKIDQENQAKIWKQIFGFAESLVLKCAVQLEIAETLHNNVKPMSLSELASKLPAQPVNEDRLYRILHFLVHMKLFNKDATTQKYSLAPPAKYLLKGWEKSMVPSILSVTDKDFTAPWNHLGDGLTGNCNAFEKALGKGIRVYMRENPEKDQLFNEGMACDTRLFASALVNECKSIFSDGINTLAGVGRGTGTAVKAISKAFPDIKCTIHDLPEITSKNSKISRDVFKSVPSADAIFMKSILHEWNDEECIQILKRCKEAIPKGGKVIIADVVIDMDSTHPYSKSRLAMDLAMMLHTGGKERTEEDWKKLIDAAGFASCKITKLSALQSVIEAYPH
What is the function of this protein?
Methyltransferase involved in the biosynthesis of the benzylisoquinoline alkaloid noscapine (By similarity).  Catalyzes the conversion of (S)-scoulerine to (S)-tetrahydrocolumbamine (By similarity).
What are the official names of this protein?
Probable scoulerine-9-O-methyltransferase OMT3B, O-methyltransferase 3b, OMT3b.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: RM21_HUMAN
Sequence: MAASSLTVTLGRLASACSHSILRPSGPGAASLWSASRRFNSQSTSYLPGYVPKTSLSSPPWPEVVLPDPVEETRHHAEVVKKVNEMIVTGQYGRLFAVVHFASRQWKVTSEDLILIGNELDLACGERIRLEKVLLVGADNFTLLGKPLLGKDLVRVEATVIEKTESWPRIIMRFRKRKNFKKKRIVTTPQTVLRINSIEIAPCLL
What are the official names of this protein?
39S ribosomal protein L21, mitochondrial, L21mt, MRP-L21, Mitochondrial large ribosomal subunit protein bL21m.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: U512F_DICDI
Sequence: MAIFKSISSISNSTGSMGSSISASNLDGIDSNNNSIACFDGGCGGSGLGGWSGFNGLDGIGGFNGGCSGGSNTNIINLDIDIGRRRHRRCC
What are the official names of this protein?
UPF0512 protein F.
What is the protein family that this protein belongs to?
Belongs to the UPF0512 family.
Protein: HSCB_SALCH
Sequence: MDYFTLFGLPARYQIDTQALSLRFQDLQRQYHPDKFANGTQAQQLAAVQQSATINQAWQTLRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLTLCEELDDIEQSKDDVRLESFIKRVQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: YDET_ECOLI
Sequence: MSGYTVKPPTGDTNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASRQSYWNTSRSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNASYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYSSLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQIGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGQLQVSWGKDKNSNCIVEYKLPEVSPGTLLNQQTAICR
What are the official names of this protein?
Fimbrial usher domain-containing protein YdeT.
Protein: HMDH_CAMAC
Sequence: MDVRRRSINSIHQIPSVGGTAPPMLKPKQPTKVDAVDLPDSPKASDALPLPLYITNGVFFTLFFTVVYYLLVRWREKIRNSTPLHVVTLSEIAAIFTFVASFIYLLGFFGIGLVQPFTSRSSHDDVWGVDDDEDVDEIVLKEDTRTVPCAAAPVDCPLPPIKPKVVDPVPISPPSSEEDEEIIKSVVEGTTPSYALESKLGDSHRAAAIRREALQRMTKKSLAGLPLDGFDYDSILGQCCEMPVGYVQIPVGIAGPLLLDGREYSVPMATTEGCLVASTNRGCKAIFACGGATSVLLRDAMTRAPVVRFGSAKRAADLKFFLENPLNFETLAAVFNSSSRFGKLQNIKCAIAGKNLYMRYSCSTGDAMGMNMISKGVQNVLDFLQDDFPDMDVIGISGNYCSDKKPAAVNWIEGRGKSVVCEAVIKEEVVKKVLKTNVASLVELNMLKNLTGSAMAGALGGFNAHASNIVSAVYLATGQDPAQNVESSHCITMMEAINDGKDLHVSVTMPSIEVGTVGGGTQLASQSACLNLLGVKGASKEAPGSNARLLATIVAGSVLAGELSLMSAIAAGQLVNSHMKYNRSNKDVTKASS
What is the function of this protein?
Catalyzes the synthesis of mevalonate.  The specific precursor of all isoprenoid compounds present in plants.
What are the official names of this protein?
3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the HMG-CoA reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NDPA_SHEB2
Sequence: MSINIEHAIIHEISQDSQGQLRCRLRPQPLLNGQAVEVMLDELHQTYTGKAGKGFGYFGIHGDDGEANPAFANALTQYRGGDLGFVEFSGQASKLLQEELSKYDFSQGGFLLMSCYTSITSDYLFVALLSAKSSMTVLDDMELSQNNHLDLNNIQLAARIDLTEWQADKDSRKYISFIRGRAGRKVADFFLDFMGCVEGVNTKAQNKTLMNAVEDFVASSELTKDERQQCRNKVFEYCSERFDEGADIEIKDLADELADQGMDSFYDFARGGSYDLDEEFPADKSTLRQLKKFSGTGGGVTLSFDGGHLGQRVIYDPISDTILIKGVPANLKDQLDRRLKGE
What are the official names of this protein?
Nucleoid-associated protein Sbal223_1817.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RING3_ARATH
Sequence: MGCVSSCFRVEDIDEYMNPNSSVYRNCPCIRCLAHNFLNLYISVFRRGETRSLPSSVQATASITSSSSHDNFLSEAFRSTPRPLPYDADPRYFRSLVSRREKGSSHSHEEVEPLRSDSDADSESFGVGGCKWANNKSTLSDKDSKEEYSSKSSLRILRSRSKSIMADSENMYILSEDEDVCPTCLEEYTSENPKIVTKCSHHFHLSCIYEWMERSENCPVCGKVMEFNETP
What is the function of this protein?
Mediates E2-dependent protein ubiquitination.
What are the official names of this protein?
E3 ubiquitin-protein ligase At3g02290, RING finger protein At3g02290, RING-type E3 ubiquitin transferase At3g02290.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCU2_ARATH
Sequence: MAMRKLLSKKLFNITNVASQSLMNCRISSSSLAVRTRVPNDSTDTTKIAPEPGDLAMSRRFMHNSAMIRPAEIMQMPVGESLIEKLREIDGSKDRIRLDGLSPPERETSLTVADTKKLLRAAQIEIVKSKLRETGRSWMPYKEFVSVCGEASSDPDLGSKIAKMLDDSANVIVLGDSVCIRPDQVTKSIEGLLPLPKIHNPNDPRRIEFKELEAEKAVIDVKAHTLVRKELWAGLGYLILQTAGFMRLTFWELSWDVMEPICFYVTSVYFMAGYAFFLRTSKEPSFEGFYQSRFEAKQRKLMNEYEFDLERYNELKKLFCSKPSDHVSKILGAIKS
What is the function of this protein?
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria.  Constitutes a pore-forming and calcium-conducting subunit.  Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
What are the official names of this protein?
Calcium uniporter protein 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MCU (TC 1.A.77) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PHK_STRCO
Sequence: MSVDTQQAPPEPTDEELAGLDAHWRAANYLAVGQIYLMANPLLTDPLRPEHVKPRLLGHWGTSPGLNLVHTHLNRVIKARDLDALCVWGPGHGGPAVLANAWLEGSYTETYPDITRDAAGMARLFKQFSFPGGVPSHVAPETPGSIHEGGELGYALSHAYGAAFDHPDLVVACVIGDGEAETGPLATSWHSNKFLDPVHDGAVLPILHLNGYKIANPTVLARLPETELDELLRGYGHDPVHVTGDDPAAVHRATARAMDTALDRIAAIQRAAREEGATGRPRWPMIVLRTPKGWTGPAEVDGLPVENTWRAHQVPLSAVRTNPEHLAQLERWLRSYRPEELFDDAGAPRPAVLAAIPEGPRRLGATPYANGGLLLRELPVPPLEKYAVPVGEPGASTHEPTRVLGDLLRDVMAATTDRRDFRLVGPDETASNRLQAVYAATGKAWQERTLPVDEDLDRHGRVMEILSEHTCQGWLEGYLLTGRHGLFSCYEAFVHIVDSMVNQHVKWLRVTRRLPWRAPIASLNYLLTSHVWRQDHNGFSHQEPGFVDHILNKSPEAVRVYLPPDANTLLSVADHALRSRDYVNVIVAGKQPCFDWLTMDQAKAHCARGAGIWDWAGTEDGSREPDVVLACAGDVPTLEILAAAQLIRHHLPELAVRVVNVVDIARLLPSGEHPHGMSDFEYDGLFTADKPVIFAYHGYPWLIHRLAYRRTGHAHLHVRGYKEIGTTTTPFDMVVGNDLDRYRLVMDVIDRVPGLAVRAAAVRQRMEDARQRHHDWIREHGVDLPEVADWTWEAPR
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: KAD_ONYPE
Sequence: MILILLGPPGIGKGTQASVLSDILKINHIATGDIFRKNFKENTELGILIKKIIAQGLLVPDDITNQMIADYLSKDIATKDFLLDGFPRNVLQARFLDDFFKNSHLFLTKVIYFNAGTQDLMKRIVGRRICPECGKVYHIENIPPKTPGICDKDQKTLIQREDDKPETFLKRLKVFNQETLPLVQYYREQNQLFEVDGMQNIDQVTKMILEVLETDRK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y864_ARCFU
Sequence: MLERPTGVTVLAILYVLAAVFFFLAAAVSGYLAQVASTTQLGEIPYAELFFAFSGIFFSITGTVWLITAYGLWKGRGWGWWLAVIFTAFGLISSLLSLPKGVVGIVVLGAILYYLTRRHVREFFGV
What are the official names of this protein?
Uncharacterized protein AF_0864.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PI3R4_RAT
Sequence: MGNQLAGIAPSQILSVESYFSDIHDFEYDKSLGSTRFFKVARAKHREGLVVVKVFAIQDPTLPLTSYKQELEELKIRLHSAQNCLPFQKAAEKASEKAAMLFRQYVRDNLYDRISTRPFLNNIEKRWIAFQILTAVDQAHKSGVRHGDIKTENVMVTSWNWVLLTDFASFKPTYLPEDNPADFNYFFDTSRRRTCYIAPERFVDGGMFATELEYMRDPSTPLVDLNSNQRTRGELKRAMDIFSAGCVIAELFTEGVPLFDLSQLLAYRNGHFFPEQVLNKIEDRSIRELVTQMIQREPGQRLEADDYLKQQRGNAFPEVFYTFLQPYMAQFAKETFLSADERILVIRKDLGNIIHNLCGHDLPEKAEGESKASGLVVLVSVITSCLQTLKSCDSKLAALELILHLAPRLSVEILLDRITPYLLHFSNNSVPRVRAEALRTLTKVLALVQEVPRNDVNIYPEYILPGIAHLAQDDATIVRLAYAENIALLAETALRFLELVQLKTLNMENEPDSEEVDEATRPNGDYDTELQALHEMVQQKVVTLLSDPENIVKQTLMENGITRLCVFFGRQKANDVLLSHMITFLNDKNDWHLRGAFFDSIVGVAAYVGWQSSSILKPLLQQGLSDAEEFVIVKALNALTCMCQLGLLQKPHVYEFASDIAPFLCHPNLWIRYGAVGFITVVAHQISTADVYCKLMPYLDPYITQPVIQIERKLVLLSVLKEPVSRSIFDYALRSKDIASLFRHLHMRQKKRNGSLLDCPPPEDPAIAQLLKKLLSQGMTEEEEDKLLALKDFMMKSNRAKANAVDQSHLHDSSQKGVIDLAALGITGRQVDLVKTKQEPDEKRARKHVKQDSNVNEEWKSMFGSLEPPNIPQALPKTSDHEVVPTGKSPRSESSAGVCVPLSTSPQVSEAAHIPSKKPVIPVVSSTVLPSTYQIRITTCKTELQQLIQQKREQCNAERIAKQMMENAEWESKPPPPGWRPKGLLVAHLHEHKSAVNRIRVSDEHLLFATCSNDGTVKIWNSQKMEGKTTTTRSILTYSRIGGRVKTLTFCQGSHYLAIASDNGAVQLLGIEASKLPKSPKIHPLQSRILDQKEDGCVVDMHHFNSGAQSVLAYATVNGSLVGWDLRSSSNAWTLKHDLKSGLITSFAVDIHQCWLCIGTSSGAMACWDMRFQLPISSHCHPSRARIRRLSMHPLYQSWVIAAVQGNNEVSMWDMETGDRRLTLWASSAPPLSELQPSPHSVHGIYCSPADGNPILLTAGSDMKIRFWDLVSPERSYVVAGSTGSPSVSYYKKIIEGTEVVQEIQNKQKVGPSDDTPRRGPESLPVGHHDIITDIATFQTTQGFIVTASRDGIVKVWK
What is the function of this protein?
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis.  Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (By similarity).
What are the official names of this protein?
Phosphoinositide 3-kinase regulatory subunit 4, PI3-kinase regulatory subunit 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Late endosome. Cytoplasmic vesicle, autophagosome. Membrane; Lipid-anchor. Note=As component of the PI3K complex I localized to pre-autophagosome structures. As component of the PI3K complex II localized predominantly to endosomes. Localizes also to discrete punctae along the ciliary axoneme (By similarity).
Protein: RS5_BRADU
Sequence: MAEREQRGGRDQRGGGRERKEREERDSEFVDKLVHINRVAKVVKGGKRFGFAALVVIGDQKGRAGFGHGKAREVPEAIRKATESAKRNLTRVSLREGRTLHHDIAGRHGAGRVYLRAAPAGTGIIAGGPMRAVFETLGVQDVVAKSIGSSNPYNMVRATFDALKHQDSPRSVAARRNIKVSTLQSRRIGGDAEAAAD
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: MDM2_FELCA
Sequence: MCNTNMSVSTDGAVSTSQMPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQHEPSDSGTSVSENRCHLEGGSDQKDPVQELQEEKPSSSDLVSRPSTSSRRRTISETEEHSDELPGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPPHCNRCWALRENWLPEDKGKDKGKMPEKAKVENSTQVEEGFDVPDCKRTTVNDSRESCAEENDDKITQASQSQESEDYSQPSTSNSIIHSSQEDVKEFEREETQDKEEIVEPSFPHNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination of p53/TP53, leading to its degradation by the proteasome.  Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.  Also acts as a ubiquitin ligase E3 toward itself and ARRB1.  Permits the nuclear export of p53/TP53.  Promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma RB1 protein.  Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation.  Component of the TRIM28/KAP1-MDM2-p53/TP53 complex involved in stabilizing p53/TP53.  Also a component of the TRIM28/KAP1-ERBB4-MDM2 complex which links growth factor and DNA damage response pathways.  Mediates ubiquitination and subsequent proteasome degradation of DYRK2 in nucleus.  Ubiquitinates IGF1R and SNAI1 and promotes them to proteasomal degradation.  Ubiquitinates DCX, leading to DCX degradation and reduction of the dendritic spine density of olfactory bulb granule cells.  Ubiquitinates DLG4, leading to proteasomal degradation of DLG4 which is required for AMPA receptor endocytosis (By similarity).  Negatively regulates NDUFS1, leading to decreased mitochondrial respiration, marked oxidative stress, and commitment to the mitochondrial pathway of apoptosis (By similarity).  Binds NDUFS1 leading to its cytosolic retention rather than mitochondrial localization resulting in decreased supercomplex assembly (interactions between complex I and complex III), decreased complex I activity, ROS production, and apoptosis (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase Mdm2, Double minute 2 protein, RING-type E3 ubiquitin transferase Mdm2, p53-binding protein Mdm2.
What is the protein family that this protein belongs to?
Belongs to the MDM2/MDM4 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Nucleus, nucleolus. Nucleus. Note=Expressed predominantly in the nucleoplasm. Interaction with ARF(P14) results in the localization of both proteins to the nucleolus. The nucleolar localization signals in both ARF(P14) and MDM2 may be necessary to allow efficient nucleolar localization of both proteins. Colocalizes with RASSF1 isoform A in the nucleus (By similarity).
Protein: DNAA_BORA1
Sequence: MKEFWQTCVSRLEQELPPQQISAWIRPLVPLAYDEAQAVLRVAAPNRFKLDWVRKNFSHQIEALAAEWYQRPVQVQFELPSHSTTPRIPVTPRAAVAPVAPASAAPLAPAAPPVAAAYSAPPEPPAAPAQTSAAVDAANIVYERSRLNTDLTFENFVTGKANQLARAAALQVAENPGTSYNPLFLYGGVGLGKTHLIHAIGNAMVAAGTGVRVRYVHADQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEAMVAQRKQIIITSDTYPKELSGIDSRLISRFDSGLTVAIEPPELEMRVAILLRKAESEGVPMPEEVAFFIAKHLRSNVRELEGALRKVLAYARFHGREALNVDVCKEALKDLLSVSNGQITVENIQKTVADFYKIKVADMYSKRRPANIALPRQVAMYLAKELTQKSLPEIGDLFGGRDHTTVLHAVRKISDARAKQAELNHTLHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBIS1_ARATH
Sequence: MESQTTFKYESLAFTKLSHCQWTDYFLSVPIDESELDVITREIDILKPEVMELLSSQGDDETSKRKVLLIQLLLSLGLAFHFENEIKNILEHAFRKIDDITGDEKDLSTISIMFRVFRTYGHNLPSSVFKRFTGDDGKFQQSLTEDAKGILSLYEAAHLGTTTDYILDEALKFTSSHLKSLLAGGTCRPHILRLIRNTLYLPQRWNMEAVIAREYISFYEQEEDHDKMLLRLAKLNFKLLQLHYIKELKSFIKWWMELGLTSKWPSQFRERIVEAWLAGLMMYFEPQFSGGRVIAAKFNYLLTILDDACDHYFSIHELTRLVACVERWSPDGIDTLEDISRSVFKLMLDVFDDIGKGVRSEGSSYHLKEMLEELNTLVRANLDLVKWARGIQVPSFEEHVEVGGIALTSYATLMYSFVGMGETAGKEAYEWVRSRPRLIKSLAAKGRLMDDITDFDSDMSNGFAANAINYYMKQFVVTKEEAILECQRMIVDINKTINEELLKTTSVPGRVLKQALNFGRLLELLYTKSDDIYNCSEGKLKEYIVTLLIDPIRL
What is the function of this protein?
Involved in sesquiterpene (C15) biosynthesis.  The major product is (Z)-gamma-bisabolene with minor amounts of (E)-nerolidol and alpha-bisabolol.
What are the official names of this protein?
(Z)-gamma-bisabolene synthase 1, Terpenoid synthase 12, AtTPS12.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_GEOMG
Sequence: MTIAEQIRTIAADARQAAIAMAKLPTTAKNDLLMAMAMALISNTPHLIDENRKDLEAGEKKGLSSAMLDRLMLDEARIKAMADGLREVAGLPDPVGEVTRMWKRPNNLMVGKMRIPLGVIGIIYEARPNVTADAAALCLKAGNSVILRGGSEAIHSNLAIARILGEEMERAGIPKAALSVIPFPEREGVLEMLKQEEFIDLIIPRGGESLIRFVVEHSKIPVIKHYKGVCHVFVDASADFDMAERIVVNAKVQRPGVCNALETLLIHKDVAEAFIPRIAATLTDLKVELRGDDCVRQFAPQAKKATEEDWQAEYLELILAVRVVDGLNEAIDHINAYGSLHTEAIVTRDYHNSQRFIREVNSSTVLVNASTRFADGNQLGLGAEIGISTTKLHSFGPMGLEDLTTTKFIVYGDGQVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRA42_HUMAN
Sequence: MVNSCCGSVCSDQGCGLENCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCSPSCCQTTCCRTTCCRPSCCVSSCFRPQCCQSVYCQPTCCRPSCGQTTCCRTTCYRPSCCVSTCCRPTCSSGSCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 4-2, Keratin-associated protein 4.2, Ultrahigh sulfur keratin-associated protein 4.2.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 4 family.
Protein: POLLU_LOTJA
Sequence: MIPLPVAAANSNSNSNSNSNDEESPNLSTVIKPPLKKTKTLLPPPSSSSSNRPLHLRVSIDNNNNNNAPPPPADFSDHQWNYPSFLGTTTRKRRPSSVKPPSTSNLRFDTIPKTKTKTKTNTNTNTNTNTNTNTNTDLPPPPVPSSSPVARPQHHNHRSPPIFYLLIITCIIFVPYSSYLQYKLAKLEDHKLHLCRQSQIHFSSGHGNGKISIPIHDASFSYILSRKAALYIVLFTLILPFLLYKYLDYLPQIINFLRRTHNNKEDVPLKKRIAYMLDVFFSIYPYAKLLALLFATLFLIGFGGLALYAVTGGSLAEALWHSWTYVADSGNHAETQGTGQRVVSVSISSGGMLIFAMMLGLVSDAISEKVDSLRKGKCEVIERNHILILGWSDKLGSLLKQLAIANKSVGGGVIVVLAEKEKEEMEMDITKLEFDFMGTSVICRSGSPLILADLKKVSVSKARAIIVLASDENADQSDARALRVVLSLTGVKEGLRGHVVVEMSDLDNEPLVKLVGGELIETVVAHDVIGRLMIQCALQPGLAQIWEDILGFENAEFYIKRWPELDGLSFKDILISFPDAIPCGVKVAADGGKIVINPDDSYVMRDGDEVLVIAEDDDTYSPGSLPEVLKGFFPRIPDAPKYPEKILFCGWRRDIDDMIMVLEAFLAPGSELWMFNEVPEKEREKKLAAGGLDVFGLENIKLVHREGNAVIRRHLESLPLETFDSILILADESVEDSVAHSDSRSLATLLLIRDIQSRRLPYKDTKSTSLRLSGFSHNSWIREMQQASDKSIIISEILDSRTRNLVSVSRISDYVLSNELVSMALAMVAEDKQINRVLEELFAEQGNEMCIKPAEFYLFDQEELCFYDIMIRGRARQEIIIGYRLANQERAIINPSEKLVARKWSLGDVFVVIASGD
What is the function of this protein?
Ion channel with permeability for potassium.  Involved in perinuclear calcium spiking but not in cytosolic calcium influx.  Required for early signal transduction events leading to endosymbiosis.  Acts early in a signal transduction chain leading from the perception of Nod factor to the activation of calcium spiking.  Also involved in fungal entry into root epidermal cells during the establishment of the arbuscular mycorrhizal symbiosis.
What are the official names of this protein?
Ion channel POLLUX.
What is the protein family that this protein belongs to?
Belongs to the castor/pollux (TC 1.A.1.23) family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Note=The chloroplastic localization proposed by PubMed:15616514 is probably an overexpression artifact.
Protein: IGF2_MOUSE
Sequence: MGIPVGKSMLVLLISLAFALCCIAAYGPGETLCGGELVDTLQFVCSDRGFYFSRPSSRANRRSRGIVEECCFRSCDLALLETYCATPAKSERDVSTSQAVLPDDFPRYPVGKFFQYDTWRQSAGRLRRGLPALLRARRGRMLAKELKEFREAKRHRPLIVLPPKDPAHGGASSEMSSNHQ
What is the function of this protein?
Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion.  Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
What are the official names of this protein?
Insulin-like growth factor II, IGF-II, Multiplication-stimulating polypeptide.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PGK_PSEP1
Sequence: MTVLKMTDLDLQGKRVLIREDLNVPVKDGVVASDARILAALPTIKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVADYLSKALGRDVPLVADYLDGVAVQAGELVLFENVRFNKGEKKNADELAQKYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALKAPAKPMAAIVAGSKVSTKLDVLNSLSSVCDQLIVGGGIANTFLAAAGHPVGKSLYEPDLVDTAKAIAAKVSVPLPVDVVVAKEFAETAEATVKAIADVAADDMILDIGPQTAANFAELLKSSKTILWNGPVGVFEFDQFGNGTKVLAKAIADSAAFSIAGGGDTLAAIDKYGVSKEISYISTGGGAFLEFVEGKVLPAVAILEERAKA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.