PharMolix/UniProtQA huggingface dataset:
Protein: RBFA_MYCLE
Sequence: MADQARARRLAKRICTIVASAIEFEIKDPGLDGVTIVDVKVTADLHDATVFYTVMGRTLEDAPDYTAATAALNRAKGTLRSKVGAGTGVRFTPTLTFIRDTTSDSVARMEELLARARAADADVAQVRLRAKPAGEADPYRDKGSVAGLVGVDIADIDDDDLTDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_CHLPB
Sequence: MKRFNAIRIGELVRIAVLVMPLLLGFGAPIYAAAEVHGEAGAHEAAAVHTDEAHGEAGEHAEGGHGEGGAGDVIMHHILDSNAMEFEPFGKFPLPKIVIGGFDLSITRHVVFMWLAALILLLVFGYVGNKYKSIKSNEAPGGVANAMEALVEFIRLDVAKSNIGEGYEKHMPYLLTVFVFILVLNLLGLIPYGASATGNINVTLTLSVFTFFITQVSAIKSNGIKGYLAHLTAGTHWALWIIMIPIEVIGLFTKPFALTIRLFANMTAGHIIILSLIFISFILKSYIVAIFVSVPFSIFIYLLEIFVSFLQAFIFTMLSALFIGLGSAHEGHEAEGAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MUTL_CHLT2
Sequence: MSLSPSRIRLLDSVTVNQISAGEVIENAASVVKELIENSLDAGADEIHIETLGGGRGQIVVRDNGVGMDPEEVPVALQRHATSKIAHFADIFSLASYGFRGEALPSIASISKMEIHTARAGGLGSKTLIEKGEPVCCEPAPRQQGTTIAVHSLFYNVPMRQSFQKSPQMDRLAIRRLLENSVLSSEGIGWTWISERRQELHVAKKQGFIERVALVLGESFVQEAFFIDKQQGDLRVLGFLGSPNQHRSTRQGQRLFINNRAVESSFISKKVAEAYAWMIPAQRYPIFVLKLFLPPMWCDFNVHPQKTEVRLLQEGQISNLLVEAISEALLRRSSSLEEIVLKVPTEKIPIENEGISVPSIRPAIVSAPLSCPTFSQQPYLKTEMATIVSRDSASSSLSVVEKVRFLTSLGKVLLVEDSEGVHVVFVQAARKHLFYVSLLSERLESRLACQTFLLPPSVQMTKLEADFLQMRLEALTALGIELSRISPDSFAIESAPPFIQEEELKEWIVALAQEGALHVGESFEQLVENTVQKLVFSRNARAFDYAWLDILWKLGKPEKAFDGEMIRRLVLDDDFM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RPOB_CHLSY
Sequence: MPPLIESVVLQPLIAPIDPGADGRRSRRIERRSFARIKDAIDLPLLIETQLKSFEWFKREGLRELFDEISPITDFTGKNLELHFRDYTFGEPRYDEFECRERDLTYAAPLRVRVELRILTTGEIKESEIFLGDFPIMTDNGTFVYNGAERVVVSQLIRSPGVYFKDEKEPTSGRSLHTAKLIPNRGAWLEFETNKRDVISVKVDRKRKIPVTILLRAITAWIAEENGNGRWVPDNELDKFGHNDQIIELFRHVDTVPEHPYIHATLDKDPSRNAKEALLELYKRLRPGDPPTLENARSLIESLLFSPRRYDLAKVGRYKLNKNLWERDVRRDGAKAPDLSVRVLLPRDIFRIVEQLILLNNGHGRPDDIDHLGNRRVRTVGELIQQQFRVGLLRLERVVKERMSLQDPASATPNGLINIRPVVAAMREFFGGSQLSQFMDQTNPLAELTNKRRLSALGPGGLSRDRAGFEVRDVHHSHYGRICPVETPEGPNIGLIGTMSTFARVNEMGFLETPYRKVYNSVDNVQVWKEKGILLRDVRDLRTGDLIAAKGTRVNDEIARQITIGLLRGQILREDIVDPDTDELIAEAGTEINRALAERIVELPIKHIKIRPVVSQEVDYLSADEEDRFVIVQANAPLDQHNRFLDTIVSCRFGEDFVSERVERVDYMDVSPKQVVSVSTSLIPFLEHDDANRALMGSNMQRQAVPLLRPDAPIVGTGMEYRAARDSGQVIVARRDGVVVSTTSERIVIEEDDGNQTEYRLRKFMRSNQDTCINQRPAVVRGQRVKAGDVIADSSSTDQGELALGQNVLVAYMPWEGGNFEDAILVSERLVREDIFTSIHIEKYEVEARDTKLGPEEITRDIPNVGQESLRNLDERGIIYIGAEVQPNDILVGKITPKGETDLTAEERLLRAIFGEKAREVKDSSLRVPNGVRGKVIDVKVFSRSEGAELPVGVNQTVRVLLCQKRKISAGDKMAGRHGNKGVVSRVLPIEDMPFLPDGRPVDIILNPIGVPSRMNIGQILETHLGWAAARLGFRVATPVFDGAHEDQIKDLLVQAGLPADGKVTLYDGRTGERFDNPVTVGYAYMLKLAHLVEDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVVGRVKTYEAIVKGEPIQEAGVPESFKVLIKELQSLGLSVEVLSADEKPVELSDDLDSDIGALEGINLSGMERGEF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: BMPA_BORAP
Sequence: MNKLLLLILFEGVIFLSCSGKSGLESGIPKVSLVIDGTFDDKSFNESALNGVKKLKEEFEIELVLKESSTNSYLSDLEGLKDAGSNLIWLIGYKFSDVAKAVSLQNSEMKYAIIDPVYSNEPIPANLVGMTFRAQEGAFLTGYIAAKVSKTGKIGFLGGIEGDIVDAFRYGYEAGAKYANKDIKIFSQYIGSFSDLEAGRSVATKMYSDGIDIIHHAAGLGGIGAIEVAKELGSGHYIIGVDEDQSYLAPNNVITSTTKDVGRSLNLFTSNYLKTNTFEGGKLINYGLKEGVVGFVRNPKMIPFEVEKEIDSLSSKIINKEVIVPYNKESYEKFLKEFI
What is the function of this protein?
Not known; immunogenic protein.
What are the official names of this protein?
Basic membrane protein A, Immunodominant antigen P39.
What is the protein family that this protein belongs to?
Belongs to the BMP lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL15_STRPM
Sequence: MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIVRAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: LOXC2_ORYSJ
Sequence: MLRPQLNPSSSHHHTTTTSSSSSTQLYFASSSCIASLRRPSPPSLIAGAGCRTTRRRQQGRQRVVVRCASSSAASSASEAARRGTGSSDMAPAAVVKVKAVATIKVTVEGLLNSLRPSKAIDNIRDLIGRSLFLELVSSELEAKTGKKKATVHSYAHKVDDDDHGVVTYEADFDVPTGFGPIGAVVVTNELGQEMFLEDLNLTAGDGAGNSTVLPIRCNSWVQPKSSIDEGTPGKRIFFAKAYLPGQTPAGLRSYREEDLKQKRGNGAGQREADDRVYDYDVYNDLGNPDSNGDLARPVLGGSKQFPYPRRCRTGRPPSKKDPKSETRKGNVYVPRDEEFSEVKNAQFLLKTLQSVLHAAVPAAQSALIDNLSLNLPFPSFFVIDKLFEDGVELPGVEKLGFLHSIVPRLLELLRDSPGDKILLFDTPANVQKDKFAWLRDEEFARETLAGINPYAIELVREFPLKSKLDPAVYGPAESAITADLLEEQMRRVMTVEEAISQKRLFMLDFHDLFLPYVHKIRSLKHTTMYGSRTIFFLTDDGTLRLLAIELTRPASPSQPQWRQVFTPSTDTTKSWLWRMAKAHVRAHDAGHHELITHWLRTHCAVEPYIIAANRQLSEMHPIYQLLHPHFRYTMRINALARSRLISAAGIIELSFSPQKYSMELSSVAYDKLWRFDMEALPADLVRRGMAEEDPTAEHGLRLAIEDYPFANDGLLIWDAIKTWVQAYVARFYPDADSVAGDEELQAFWTEVRTKGHGDKKDAPWWPKLDSPESLAHTLTTIVWVAAAHHAAVNFGQYDFGGYFPNRPSIARTVMPVEEPVDGAAMERFLDNPDQALRECFPSQVQATVVMAVLDVLSTHSTDEEYLGGEQTRPWNSDAAVQAAYAGFTARLKEIEGVIDGRNKDRKLKNRCGAGILPYQLMKPFSDAGVTGMGIPNSTSI
What is the function of this protein?
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  It catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).
What are the official names of this protein?
Probable lipoxygenase 8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YEEB_SCHPO
Sequence: MRVILVIGRSNSGKLDFIKALTGSLPKGLDDEAFNNDHSGLIHKYNIRNKYFEASVGIWIEEYSNLAETLDAYSSEEAKEVIDSLGAIVYTFRSFDEAEWSLFKNFIDKLQLEIPVIGLHMSDEKLLEPPDVFTPEYISISEEGVNEFNEKVGLDRVREILDCCEWNLSQVDKSFSEEKDDAGDFYLPERFKGSPDMQSTDLDNLMKEMNQIRDADLEKNEKKAKALNLLEKLLGDEFEENDYESL
What are the official names of this protein?
Uncharacterized protein C19A8.11c.
Protein: MBF1_CANAL
Sequence: MSSDWDSVTIIGQKARVGGGGPRENVAKTSSQLNAARRAGLVVGTEKKYGTANTKSNPEGQRLTKLDATDDVVAVKKVDVSVGKAIQQARQEKKLTQKELATKVNEKPNVINDYEAGRAIPNQQLLAKLERALGVKLRGKNIGEPLFAKKK
What is the function of this protein?
Transcriptional coactivator that stimulates transcriptional activity by bridging regulatory proteins and TBP, thereby recruiting TBP to promoters occupied by DNA-binding regulators.
What are the official names of this protein?
Multiprotein-bridging factor 1.
What is the protein family that this protein belongs to?
Belongs to the MBF1 family.
Protein: YVRO_BACSU
Sequence: MLTLNNISKSYKLGKEEVPILKHINLTVQAGEFLAIMGPSGSGKSTLMNIIGCLDRPTSGTYTLDQIDILKGKDGALAEIRNESIGFVFQTFHLLPRLTALQNVELPMIYNKVKKKERRQRAYEALEKVGLKDRVSYKPPKLSGGQKQRVAIARALVNQPRFILADEPTGALDTKSSEQILALFSELHREGKTIIMITHDPDVAKKADRTVFIRDGELVLDERGDISHA
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YvrO.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: RL20_DELAS
Sequence: MPRVKRGVTARARHKKVLALSKGFRGRRGNVFRIAKQAVMKAGQYAYRDRRAKKRVFRRLWIARINAAARELGLTYSQFANGLKKAAIEIDRKMLADIAVHDKAAFSSIVDQVKAKLAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PTER_DROYA
Sequence: MSTVQTVLGTITPNLLGRTLTHEHVALDFEHFYRPPPPDFESELKAKISMSTLGYVRLYPYSSKENVRFYDEEALEAAKKDVLLYKKHGGGSIVENSSYGLKRNLEFIVELAKSTGVHFIAGTGHYIHAMQDASHASLTVEQMSDLYSKDIITGQQVNGQMVKCGFIGEVASVYPIHDFEKNAIKAAGEIQEVLGCGVSMHPHRVTKAPFEIMRLYLEAGGRADKCVMSHLDRTIFDIDELLEFAKLGCYIQYDLFGTECSFYQLNTSVDMISDGQRIDNLIKLIKEGLVDKLLMSHDIHTKHRLTSYGGHGYHHIHTNILPRMFDRGVTLEQVEQMTVTNPANWLAFDP
What are the official names of this protein?
Phosphotriesterase-related protein, Parathion hydrolase-related protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
Protein: HSV2_ASHGO
Sequence: MKTRNPIVVQRKNGPPRFLHVNFNQDQECFSCATEKGFEIYNTDPIQCSVKRRFSHNGMSGIGYTRMLYRTNYIGLVGGGASPRFSTNKIAIWDDIQQRDSVSIRFNSPVHELFLSRQYIVVVLAQSIDVYTFSGSPSRVCPVISNIHNGIADFVTCSKMRRASGPQDVEHALSQKHVIAGILAYPSGIRPGQIHIADLSNIQTPSVADASATHLPTSIIKAHKNPIHLVKLSPQGTMVATCSVEGTLIRVFSIASGSLIHEFRRGLDRALIYDMQWNGKGDKLAVVSDKFTLHIFQINEDLDKRHLLKGWFPKVKYLQGVWSMCSTKLDRSLLTHDEDTCKVGWIGDEALSLLWQKSGMWEKYVIMEKLREYKVDETLHSGAPDGRRQLYDLVRESWRQL
What is the function of this protein?
Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways.
What are the official names of this protein?
SVP1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Vesicular and vacuolar.
Protein: FTHS_STAAM
Sequence: MTHLSDLDIANQSTLQPIKDIAASVGISEDALEPYGHYKAKIDINKITPRENKGKVVLVTAMSPTPAGEGKSTVTVGLADAFHELNKNVMVALREPALGPTFGIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALSAFIDNHIHQGNELGIDQRRIEWKRVLDMNDRALRHVNVGLGGPTNGVPREDGFNITVASEIMAILCLSRSIKDLKDKISRITIGYTRDRKPVTVADLKVQGALAMILKDAIKPNLVQSIEGTPALVHGGPFANIAHGCNSILATETARDLADIVVTEAGFGSDLGAEKFMDIKAREAGFDLAAVVVVATIRALKMHGGVAKDNLKEENVEAVKAGIVNLERHVNNIKKFGVEPVVAINAFIHDTDAEVEYVKSWAKENNVRIALTEVWEKGGKGGVDLANEVLEVIDQPNSFKPLYELELPLEQKIEKIVTEIYGGSKVTFSSKAQKQLKQFKENGWDNYPVCMAKTQYSFSDDQTLLGAPSGFEITIRELEAKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTDDGHAIGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: DEN11_DANRE
Sequence: MVEQSDRAPLLDWEEIPPAELAPSVPSPDTGDSLQSGLSSYPTEATLGADITLNTSPTRPSSVAAVHSPHKQHSGPGGDALAEEDEPGDCAFHGLSVRDRRITGWEEKDQIVAVFVVTFDTRSGNMIEWCLPHDVNLEGVEFKSMASGSHRISSDFIYFRKGCYFGLACFANMPVESELERGARMKSVGILSPSYTLLYRYMHFLENQVRHQLQCPGQYSPLEAFYEDKKAVLPSGGNGLVTACPTSALAPIVNRCMHPEMKITHPAGCMSQFIRFFGEQIMVLWKFALLRKRILIFSPPPVGVVCYRVYCCCCLANVSIPGMGVSVPEFRPFFYINVADIPALETELSYVACTTEKIFEEKKELYDVYIDNQNVKTHRESLQPLLRLNSADREKYRKLCEQRQLLLYSQEVDGDCTSNEEDLFILFFMEQNNRIFQTLSEVAVSADPTLTAEHVRAMGLDPQGDRGFLVDLLEIYGIDVMLVIDNPCCP
What is the function of this protein?
Probable guanine nucleotide exchange factor (GEF).  May promote the exchange of GDP to GTP, converting inactive GDP-bound small GTPases into their active GTP-bound form.
What are the official names of this protein?
DENN domain-containing protein 11, DENND11, Protein LCHN.
What is the protein family that this protein belongs to?
Belongs to the DENND11 family.
Protein: REV_HV1ND
Sequence: MAGRSGDSDENLLKAIRLIKFLYQSNPPPSPEGTRQARRNRRRRWRARQRQIHSIGERIICTFLGRPEEPVPLQLPPLERLNLNCSEDCGTSGTQGVGSPQIPVEPPAVLESGTEE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: PKS41_DICDI
Sequence: MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK
What is the function of this protein?
Probable polyketide synthase.
What are the official names of this protein?
Probable polyketide synthase 41, dipks41.
Protein: MGSA_BORAP
Sequence: MEKKIALIAHDKKKDDLVNFVKQNHLFLSKFKLIATGTTGSRIQQATDLTVVKYKSGPMGGDQQIGAEVAEGNVLAIFFFRDPLTSQPHEPDVSALIRLCDVHKIPLATNVKTAEILIKGLESLILR
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: DYR2_HUMAN
Sequence: MFLLLNCIVAVSQNMGIGKNGDLPRPPLRNEFRYFQRMTTTSSVEGKQNLVIMGRKTWFSIPEKNRPLKDRINLVLSRELKEPPQGAHFLARSLDDALKLTERPELANKVDMIWIVGGSSVYKEAMNHLGHLKLFVTRIMQDFESDTFFSEIDLEKYKLLPEYPGVLSDVQEGKHIKYKFEVCEKDD
What is the function of this protein?
Key enzyme in folate metabolism.  Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.  Required to prevent uracil accumulation in mtDNA.  Binds its own mRNA and that of DHFR.
What are the official names of this protein?
Dihydrofolate reductase 2, mitochondrial, Dihydrofolate reductase, mitochondrial, Dihydrofolate reductase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane.
Protein: HEMH_WOLPP
Sequence: MKKAVILFNLGGPDSLSAVRPFLFNLFYDKRIINLPNPFRFLLAKFISKRRESTAQEIYEHIGGKSPILENTKAQADALELKLNENGNHVYKIFICMRYWHPFADEVVKSVKQFDPDEIILLPLYPQYSTTTTLSSIENWQKNAKLECNTKTIHHYYDNEDFIEAHVNLTSKYYKLASKIGKPRVLFSAHSLPLSIIKKGDPYASQIEKTVKLIVKKLNIEDLDWGICYQSKVGPVKWLEPSTESELSRAKDDNIPVVLSPISFVSEHSETLVELDIEYKAIIKDGYYFRVPTLSTDLLFIKCLADLCLDHSQSTDL
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_CERS5
Sequence: MGQKVNPIGMRLQVNRTWDSRWFAESKDYGNLLLEDLKMREFIHDYAKQAGVSKVIIERPHRKCRVTIHTARPGVIIGKKGADIETLRKKLAAFTKSELHLNIVEIRKPELDAQLVAESIAQQMERRVSFRRAMKRGVQNAMRIGALGIRVNVAGRLGGAEIARTEWYREGRVPLHTLRADIDYATSEASTPYGIIGVKVWIFKGEILEHDPQAHDRRHSEAQEGAAPRPPRRDRERA
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: OR5B3_HUMAN
Sequence: MENKTEVTQFILLGLTNDSELQVPLFITFPFIYIITLVGNLGIIVLIFWDSCLHNPMYFFLSNLSLVDFCYSSAVTPIVMAGFLIEDKVISYNACAAQMYIFVAFATVENYLLASMAYDRYAAVCKPLHYTTTMTTTVCARLAIGSYLCGFLNASIHTGDTFSLSFCKSNEVHHFFCDIPAVMVLSCSDRHISELVLIYVVSFNIFIALLVILISYTFIFITILKMHSASVYQKPLSTCASHFIAVGIFYGTIIFMYLQPSSSHSMDTDKMAPVFYTMVIPMLNPLVYSLRNKEVKSAFKKVVEKAKLSVGWSV
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5B3, Olfactory receptor 5B13, Olfactory receptor OR11-239.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXS_ECOUT
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: LSPA_RHOPA
Sequence: MTPVRLGVLAGIVALVLDQVTKLWLLYGFELARKGVVQVLPFFDLVLAWNTGISYGWFSGQGPTGQILMLAFKAVAIVALAIWMARSTTKLATIGLGLIIGGAIGNAIDRLAYGAVVDFALLHAEIGGKIYNWYVFNIADVAIVVGVAALLYDSLIGLPAAKAP
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLYA_BACVZ
Sequence: MKHLPVQDKQVFNAIKDERKRQQTKIELIASENFVTEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRAKEIFGAEHVNVQPHSGAQANMAVYFTILEHGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDKDTQYIDYEDVREKALAHKPKLIVAGASAYPRTIDFKKFREIADEVGAYFMVDMAHIAGLVAAGLHPNPVPYADFVTTTTHKTLRGPRGGMILCREEFGKKIDKSIFPGIQGGPLMHVIAAKAVSFGEVLEDDFKTYAQNVISNAKSLAESLNKEGIQLVSGGTDNHLVLVDLRSLGLTGKVAEHVLDEIGITSNKNAIPYDPEKPFVTSGIRLGTAAVTSRGFDGDALEEVGAIIGLALKHHEDEAKLEEARQRVSALTEKFPLYKELGY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.