PharMolix/UniProtQA huggingface dataset:
Protein: Y3513_CHRVO
Sequence: MSLTTLPGVCGIGLRAPHYREALDARPELGWVEVHSENFFDGGTPLAMLRRVAECWPLSLHGVGLGLGSAARPDRGHLASLRRLVDETCPAAVSEHLSFNHSPHRYVNDLLPIPYTRAALDTVAGHVSETQDALGRTILLENLSSYVEFPDNEMNEGEFLAELVRITGCGVLLDVNNLYVNRINLGTDTDAVLAALPPDAIGEIHLAGYSEREGMLVDTHSQAVHDEVWRFYREVIRRIGPRPTLIEWDLDIPPLATLQAEAAKAQAILGGADERS
What are the official names of this protein?
UPF0276 protein CV_3513.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: RL35_AZOC5
Sequence: MPKMKTKSGAKKRFRLTGTGKVIAGQAGKRHGMIKRTNKTIRNQRGTNILCESDGRIIRKSFLPNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RSMA_STRR6
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDILKVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLAEFAGLADALKGQGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPT_ECOSE
Sequence: MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANVPGNIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVDRADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHIIDIAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAQRKS
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_SHEHH
Sequence: MSLSVEAKAQILAEFGRCENDTGSSEVQVALLTAQINHLQGHFKEHIHDHHSRRGLLRMVSTRRKLLAYLKRTENVRYQELIKKLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: YD009_YEAST
Sequence: MKALSVLCFHNPFKRCLGQKSFFVGDSFFIPTPKRLVLGKLRLSNYTAFHDLIIHDLFIYIFILNFFFFPFCNNFNYWKVFHVAQPRIYHHSRLVMILKVSLECAVS
What are the official names of this protein?
Uncharacterized protein YDL009C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EUTD_ECOLI
Sequence: MIIERCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPILVANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTDPLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGPALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANVQQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIGYKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQTLVE
What is the function of this protein?
When expressed independently of the eut operon it can restore growth to a double pta-acs deletion mutant.
What are the official names of this protein?
Phosphate acetyltransferase EutD, Ethanolamine utilization protein EutD.
What is the protein family that this protein belongs to?
Belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=It is not clear if this enzyme is found in the cytoplasm or the bacterial microcompartment.
Protein: ADHR_DROSU
Sequence: MYDLTGKHVCYVADCGGIALETSKVLMTKNIAKLAILQSVENQPAIARLQSIKHSTQIFFWTFDVTMARQEMKKYFDEVMVQMDYIDVLINGATLCDERNIDATINTNLTGMMNTVATVLPYMDRKMGGSGGLIVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYTQNGVAVMAVCCGPTKVFVDRELNAFLEYGQTFADRLRRAPCQSTAVCGQNIVTAIERSENGQIWIADKGGLELLTLHWYWHMADQFLSYMQSTDDENQEQFVSGQR
What are the official names of this protein?
Alcohol dehydrogenase-related 31 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: FECE_ECOLI
Sequence: MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTLLNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRNPWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVVLLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMAQGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR
What is the function of this protein?
Part of the binding-protein-dependent transport system for citrate-dependent Fe(3+).  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Fe(3+) dicitrate transport ATP-binding protein FecE, Iron(III) dicitrate transport ATP-binding protein FecE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CCL4_MACMU
Sequence: MKLCVTVLSLLVLAAAFCSPALSAPMGSDPPTSCCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRGKQVCADPSETWVQEYVNDLELN
What is the function of this protein?
Monokine with inflammatory and chemokinetic properties.
What are the official names of this protein?
C-C motif chemokine 4, Macrophage inflammatory protein 1-beta, MIP-1-beta, Small-inducible cytokine A4.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AMPP1_AJECG
Sequence: MGPIDTSQRLARLRELMQERKVDVYIVPSEDSHQSEYIAHCDGRREFISGFTGSAGCAIVSMTKAALSTDGRYFNQAAKQLDNNWILLKRGFENMPTWQEWTAEQAEGGKVVGVDPSLITASDARNLSETIKKCGGSLLGVQENLVDLVWGTERPARPSEKVALHPIEFAGKSFEEKISDLRKELQKKKSAGFVISMLDEIAWLFNLRGNDIPYNPVFFAYAIITQSTADLYIDEEKLPAEVKNYLGDKVSLKPYSSIFEDAKVLGQSAQNKSDGEASAKPPQKFLISTRASWSLSLALGGEKNVEEVRSPITDAKAIKNEAELEGMRACHIRDGAALSEYFAWLENELVNKKTVLNEVDASDKLEQIRSKHQHFVGLSFDTISSTGPNAAVIHYKAERNNCSIIDPKAVYLCDSGAQYLDGTTDTTRTLHFGEPTEMEKKAYTLVLKGLISIDTAVFPKGTTGFALDAFARQYLWKEGLDYLHGTGHGVGSYLNVHEGPIGLGTRVQYSEVAIAPGNVISDEPGYYEDGVFGIRIENIIMAKEVKTTHKFGEKPWLGFEHVTMTPLCQKLINPSLLSDAEKKWVNDYHTEIWEKTSKYFENDELTRNWLKRETQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: LCTP_HALH5
Sequence: MLVETYDPFQHLAVSAFVAAIPILLLLLCLTVFKMQGIQAALLTLLVTFFIAGLVFHLPFGESIGSIVQGVVQGLWPIGYIIVMAVWLYKIAVASGKFAVLRGSIIGISRDQRIQLLLIGFCFNAFLEGAAGFGVPIAICAVLLVSLGFKPLQAAMLCLIANGASGAFGAIGIPVGIIDTLGLEGQVTSMDVSMMTALTLPMINFTIPFLLIWLMDSWKGIKEILPAILVTSSVYTVSQALITIFIGPELADIIPSLLTMGLLALFLKRWQPRNTFLLNGNGCESEHASLKDVIKAWSPFYLLTMFVFLWSLPAFKGLLAEGGALEFAKWAFVVPGSSIEVGVDFIGATGTAILLAAVTTVTTTKMIRMKESISLLKKVIVDFSIPIMMICAIIGIAKLMTYGGLTMALGEAVATTGAFFPFLSPILGWIGVFMTGSVVNNNTLFAPIQTTAGAIIGTNPSLLVAANTAGGVMAKLVSPQSIAIATAAVGETGNEAALTKMTLKYSFGLLVFVSVWTYILSLLF
What is the function of this protein?
May play a role in L-lactate transport.
What are the official names of this protein?
L-lactate permease.
What is the protein family that this protein belongs to?
Belongs to the lactate permease family.
Protein: KES1_YEAST
Sequence: MSQYASSSSWTSFLKSIASFNGDLSSLSAPPFILSPISLTEFSQYWAEHPELFLEPSFINDDNYKEHCLIDPEVESPELARMLAVTKWFISTLKSQYCSRNESLGSEKKPLNPFLGELFVGKWENKEHPEFGETVLLSEQVSHHPPVTAFSIFNDKNKVKLQGYNQIKASFTKSLMLTVKQFGHTMLDIKDESYLVTPPPLHIEGILVASPFVELEGKSYIQSSTGLLCVIEFSGRGYFSGKKNSFKARIYKDSKDSKDKEKALYTISGQWSGSSKIIKANKKEESRLFYDAARIPAEHLNVKPLEEQHPLESRKAWYDVAGAIKLGDFNLIAKTKTELEETQRELRKEEEAKGISWQRRWFKDFDYSVTPEEGALVPEKDDTFLKLASALNLSTKNAPSGTLVGDKEDRKEDLSSIHWRFQRELWDEEKEIVL
What is the function of this protein?
Lipid transport protein (LTP) involved in non-vesicular transfer of lipids between membranes.  Functions in phosphoinositide-coupled directional transport of various lipids by carrying the lipid molecule in a hydrophobic pocket and transferring it between membranes through the cytosol.  Involved in maintenance of intracellular sterol distribution and homeostasis (PubMed:20008566, PubMed:15173322, PubMed:16136145, PubMed:22162133).  Involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum.  Specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is delivered to the ER-localized PI4P phosphatase SAC1 for degradation.  Thus, by maintaining a PI4P gradient at the ER/Golgi interface, SAC1 may drive PS transport (PubMed:25849868, PubMed:16136145, PubMed:22162133).  Displays a similar affinity for PI4P and sterols (PubMed:22162133).  Binds sterol and PI4P in a mutually exclusive manner (PubMed:22162133).  Involved in ergosterol transport from the plasma membrane (PM) to the ER (PubMed:16585271).  Mediates sterol transport from the ER to mitochondria (PubMed:29487131).  Involved in the negative regulation of Golgi-derived transport vesicle biogenesis (PubMed:8978672).  Plays a role in the positive regulation of vesicular transport of ceramide from the ER to the Golgi, negatively regulating COPII-mediated ER export of cargos (PubMed:24213531).
What are the official names of this protein?
Oxysterol-binding protein homolog 4, Bypass SECl4 recessive protein 3, KRE11-1 suppressor protein 1, Protein KES1, Oxysterol-binding protein-related protein 4, ORP 4, OSBP-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane.
Protein: RS21_STUS1
Sequence: MPAVKVKENEPFDVALRRFKRSCEKAGVLAEVRSREFYEKPTAERKRKAAAAVKRHAKKVQREQRRSVRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: YI036_YEAST
Sequence: MLLPDFLHQRFHSRPVRDVEDTIDKFVCTVFSLQRLQTSFRSCYAVDDAFIVLFDNSFHQLQANPTGGTCNQNNLAHIPSLTDYKLFLLLLFATALISCIPSSFSALSFLATLRKRSKSEKKREKTMRNSMLP
What are the official names of this protein?
Putative uncharacterized membrane protein YIR036W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CRIP2_BOVIN
Sequence: MASKCPKCDKTVYFAEKVSSLGKDWHRFCLRCEHCSKTLTPGGHAEHDGKPFCHKPCYATLFGPKGVNIGGAGSYIYEKPSAEKPQVTGPIEVPVARTEERKASGPPKGPSKASSVTTFTGEPNMCPRCNKRVYFAEKVTSLGKDWHRPCLRCERCGKTLTPGGHAEHDGQPYCHKPCYGILFGPKGVNTGAVGSYIYDKDPEGKAQP
What are the official names of this protein?
Cysteine-rich protein 2, CRP-2.
Protein: DPP4_NEOFI
Sequence: MKWSILLLVGCAAAIDVPRQPYAPTGSGKKRLTFNETVVKRAISPSAISVEWISTSEDGDYVYQDQDGSLKIQSIVTNNTQTLVPADKVPEDAYSYWIHPNLSSVLWATNYTKQYRHSYFADYFIQDVQSMNLRPLAPDQSGDIQYAQWSPTGDAIAFVRGNDVFVWTNASTSQITNDGGPDLFNGVPDWIYEEEILGDRFALWFSPDGAYLAFLRFNETGVPTFTVPYYMDNEEIAPPYPRELELRYPKVSQTNPTVELNLLELRTGERTPVPIDAFDAKELIIGEVAWLTEKHDVVAVKAFNRVQDRQKVVAVDVASLRTKTINERDGTDGWLDNLLSMAYIGPIGESKEEYYIDISDQSGWAHLWLFPVAGGEPIALTKGEWEVTAILSIDKPRQLVYFLSTKHHSTERHLYSVSWKTMEITPLVDDTVPAVWSASFSSQGGYYILSYRGPDVPYQDLYAINSTAPLRTITSNAAVLDGLKEYTLPNITYFELALPSGETLNVMQRLPVKFSSKKKYPVLFTPYGGPGAQEVSKAWQALDFKAYIASDPELEYITWTVDNRGTGYKGRAFRCQVTSRLGELEAADQVFAAQQAAKLPYVDADHIAIWGWSYGGYLTGKVIETDSGAFSLGVQTAPVSDWRFYDSMYTERYMKTLESNAAGYNASAIRKVAGYKNVRGGVLIQHGTGDDNVHFQNAAALVDTLVGAGVTPEKLQVQWFTDSDHGIRYHGGNVFLYRQLSKRLYEEKKRKEKGEAHQWSKKSVL
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl peptidase 4, Dipeptidyl peptidase IV, DPP IV, DppIV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Secreted.
Protein: EF1A_CHICK
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSSNMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMIPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAGGAGKVTKSAQKAQKAK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 1, EF-1-alpha-1, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2289_STAAW
Sequence: MKRLVTGLLALSLFLAACGQDSDQQKDGNKEKDDKAKTEQQDKKTNDSSKDKKDNKDDSKDVNKDNKDNSANDNQQQSNSNATNNDQNQTNNNQANNNQKSSYVAPYYGQNAAPVARQIYPFNGNKTQALQQLPNFQTALNAANNEANKFGSNNKVYNDYSIEEHNGNYKYVFSFKDPNANGKYSIVTVDYTGQAMVTDPNYQQ
What are the official names of this protein?
Uncharacterized lipoprotein MW2289.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GFRA2_HUMAN
Sequence: MILANVFCLFFFLDETLRSLASPSSLQGPELHGWRPPVDCVRANELCAAESNCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMKKELQCLQIYWSIHLGLTEGEEFYEASPYEPVTSRLSDIFRLASIFSGTGADPVVSAKSNHCLDAAKACNLNDNCKKLRSSYISICNREISPTERCNRRKCHKALRQFFDRVPSEYTYRMLFCSCQDQACAERRRQTILPSCSYEDKEKPNCLDLRGVCRTDHLCRSRLADFHANCRASYQTVTSCPADNYQACLGSYAGMIGFDMTPNYVDSSPTGIVVSPWCSCRGSGNMEEECEKFLRDFTENPCLRNAIQAFGNGTDVNVSPKGPSFQATQAPRVEKTPSLPDDLSDSTSLGTSVITTCTSVQEQGLKANNSKELSMCFTELTTNIIPGSNKVIKPNSGPSRARPSAALTVLSVLMLKLAL
What is the function of this protein?
Participates in NRTN-induced 'Ser-727' phosphorylation of STAT3.
What are the official names of this protein?
GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: PLSX_THEFY
Sequence: MSSPVTAQRPPAAPPLIAVDAMGGDHAPREIVAGAVRAVREHGLRLALVGRSSELAPLVAAEQAARELPIVHAEEALAMHEGALAAWRRARSSVAVGCKLVRQGTAAALVSAGSTGGVVSTATVRLRTLPGVLRPALALVLPTTPTPTILLDAGANADAKPEMLVQFAHLGAAYARVGHGIAEPRVGILTIGSEPGKGNKLARRAAELLSANATEDRLDFRGNIEGHDLLAGLVDVVVTDGFTGNVALKSVEGAVRFAFDEIRAALTSSPLARFGTLFQRRALRELRTRFDSETYGGAVLLGLNGTVVIAHGASRAEGIAHACLLAHNLVVGRITDQIRRGIAGVSRTPSWLHRLSAPEE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PPSB_MYCBO
Sequence: MMRTAFSRISGMTAQQRTSLADEFDRVSRIAVAEPVAVVGIGCRFPGDVDGPESFWDFLVAGRNAISTVPADRWDAEAFYHPDPLTPGRMTTKWGGFVPDVAGFDAEFFGITPREAAAMDPQQRMLLEVAWEALEHAGIPPDSLGGTRTAVMMGVYFNEYQSMLAASPQNVDAYSGTGNAHSITVGRISYLLGLRGPAVAVDTACSSSLVAVHLACQSLRLRETDLALAGGVSITLRPETQIAISAWGLLSPQGRCAAFDAAADGFVRGEGAGVVVLKRLTDAVRDGDQVLAVVRGSAVNQDGRSNGVTAPNTAAQCDVIADALRSGDVAPDSVNYVEAHGTGTVLGDPIEFEALAATYGHGGDACALGAVKTNIGHLEAAAGIAGFIKATLAVQRATIPPNLHFSQWNPAIDAASTRFFVPTQNSPWPTAEGPRRAAVSSFGLGGTNAHVIIEQGSELAPVSEGGEDTGVSTLVVTGKTAQRMAATAQVLADWMEGPGAEVAVADVAHTVNHHRARQATFGTVVARDRAQAIAGLRALAAGQHAPGVVSHQDGSPGPGTVFVYSGRGSQWAGMGRQLLADEPAFAAAVAELEPVFVEQAGFSLRDVIATGKELVGIEQIQLGLIGMQLTLTELWRSYGVQPDLVIGHSMGEVAAAVVAGALTPAEGLRVTATRARLMAPLSGQGGMALLGLDAAATEALIADYPQVTVGIYNSPRQTVIAGPTEQIDELIARVRAQNRFASRVNIEVAPHNPAMDALQPAMRSELADLTPRTPTIGIISTTYADLHTQPIFDAEHWATNMRNPVRFQQAIASAGSGADGAYHTFIEISAHPLLTQAIADTLEDAHRPTKSAAKYLSIGTLQRDADDTVTFRTNLYTADIAHPPHTCHPPEPHPTIPTTPWQHTHHWIATTHPSTAAPEDPGSNKVVVNGQSTSESRALEDWCHQLAWPIRPAVSADPPSTAAWLVVADNELCHELARAADSRVDSLSPPALAAGSDPAALLDALRGVDNVLYAPPVPGELLDIESAYQVFHATRRLAAAMVASSATAISPPKLFIMTRNAQPISEGDRANPGHAVLWGLGRSLALEHPEIWGGIIDLDDSMPAELAVRHVLTAAHGTDGEDQVVYRSGARHVPRLQRRTLPGKPVTLNADASQLVIGATGNIGPHLIRQLARMGAKTIVAMARKPGALDELTQCLAATGTDLIAVAADATDPAAMQTLFDRFGTELPPLEGIYLAAFAGRPALLSEMTDDDVTTMFRPKLDALALLHRLSLKSPVRHFVLFSSVSGLLGSRWLAHYTATSAFLDSFAGARRTMGLPATVVDWGLWKSLADVQKDATQISAESGLQPMADEVAIGALPLVMNPDAAVATVVVAADWPLLAAAYRTRGALRIVDDLLPAPEDVGKGESEFRTSLRSCPAEKRRDMLFDHVGALAATVMGMPPTEPLDPSAGFFQLGMDSLMSVTLQRALSESLGEFLPASVVFDYPTVYSLTDYLATVLPELLEIGATAVATQQATDSYHELTEAELLEQLSERLRGTQ
What is the function of this protein?
Part of the PpsABCDE complex involved in the biosynthesis of the lipid core common to phthiocerols and phenolphthiocerols by successive additions of malonyl-CoA or methylmalonyl-CoA extender units (PubMed:9201977).  PpsA can accept as substrate the activated forms of either icosanoyl (C20), docosanoyl (C22) or lignoceroyl (C24) groups from FadD26, or a (4-hydroxyphenyl)-C17 or (4-hydroxyphenyl)-C19 fatty acyl from FadD29 (By similarity).  PpsA initiates the biosynthesis and extends its substrate using a malonyl-CoA extender unit.  The PpsB and PpsC proteins add the second and third malonyl-CoA extender units.  PpsD adds an (R)-methylmalonyl unit and PpsE adds a second (R)-methylmalonyl unit.  The incorporation of the methylmalonyl units results in formation of two branched methyl groups in the elongated product (By similarity).
What are the official names of this protein?
Phenolphthiocerol/phthiocerol polyketide synthase subunit B, (Phenol)carboxyphthiodiolenone synthase subunit B, Beta-ketoacyl-acyl-carrier-protein synthase I, Phthiocerol synthesis polyketide synthase type I PpsB.
Protein: HOLIN_BPT1
Sequence: MKEFLTAATSSTGGASLVGAATGQLYIAGATFICFLLFGAWGAYWKYRDSKAIQEALNDGDLNKALKIRGR
What is the function of this protein?
Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of nanometer-scale pores (pinholes) causing host cell membrane depolarization and endolysin refolding and release into the periplasmic space (By similarity).  Once the pinholin has permeabilized the host cell membrane, the SAR-endolysin is released into the periplasm and breaks down the peptidoglycan layer (By similarity).  Determines the precise timing of host cell lysis.  Participates with the SAR-endolysin and the U-spanin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell (By similarity).
What are the official names of this protein?
Holin, Pinholin.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass type II membrane protein.
Protein: RS32_XENLA
Sequence: MAAQMSKKRKFVADGIFKAELNEFLTRELAEDGYSGVEVRVTPTQTEIIILATRTQNVLGEKGRRIRELTAVVQKRFGFPEGSVELYAEKVATRGLCAIAQAESLRYKLLGGLAVRRACYGVLRFIMESGAKGCEVVVSGKLRGQRAKSMKFVDGLMIHSGDPVNYYVDTAVRHVLLRQGVLGIKVKIMLPWDPSGKIGPKKPLPDHVSIVEPKDEIVPTTPISEQKGAKPDQPQPPVMPQPVATA
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Has endonuclease activity and plays a role in repair of damaged DNA.  Also involved in other processes including regulation of transcription, translation of its cognate mRNA, spindle formation and chromosome movement during mitosis, and apoptosis.
What are the official names of this protein?
40S ribosomal protein S3-B, S1B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, nucleolus. Mitochondrion inner membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton, spindle.
Protein: QUEC_XYLFA
Sequence: MKKAVVLLSGGMDSAVVTAIAQSQGFMVHALSIRYGQRHTSELDAAVRIARVLNVAAHKVVDVDLRSIGGSALTDDIEIPDAGGKGIPVTYVPARNTIMLSLALGWAEVIGAADIFCGVNAVDYSGYPDCRPQFITAFETLANLATKVGVEGTQLHVHAPLQFLSKAEIVHEGVLHGVDFGLTVSCYRADVDGRACGRCDACKLRAAGFADAGVADPTRYMELPCSLLLL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: DHPR_RAT
Sequence: MAASGEARRVLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTDSFTEQADQVTAEVGKLLGDQKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGNKRPNSGSLIQVVTTDGKTELTPAYF
What is the function of this protein?
Catalyzes the conversion of quinonoid dihydrobiopterin into tetrahydrobiopterin.
What are the official names of this protein?
Dihydropteridine reductase, HDHPR, Quinoid dihydropteridine reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: AC4CH_ECO55
Sequence: MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELIKVIADIYPGQTQFYVIEFKCL
What is the function of this protein?
Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).
What are the official names of this protein?
N(4)-acetylcytidine amidohydrolase, ac4C amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the N(4)-acetylcytidine amidohydrolase family.
Protein: RIMM_THEP1
Sequence: MIRTIQDLLNERVAIGKIVNTHGLKGEVKFFPYTNSEEIVKNLSSVVLYNSEKKAFYNLTVESVRRMNKLFLIRFKSIDTIEAAERIKGCEVFIKYEELPKLSEDEYYFYEILDCDVFYESGENVGKVVDIIETGSNDVLVVRKKKKETLIPMTKDCIVEIDKGAKKIIAKEMEWI
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.