PharMolix/UniProtQA huggingface dataset:
Protein: PCH2_ORYSJ
Sequence: MSAPMEVSFSAPPPPDAASAAAAAPSLVPAVSAAAVAATTVSCSPQPPTGSPSADDRILVSVEVLLHATSTARAEDVCAAVERMLEARSLSYVDGPVPIPNDDPFLLANVKRIQICDTDEWTENHKVLLFWQVRPVVHVFQLSEDGPGEEPGEDDTLSSFNEWALPAKEFDGLWESLLYEVGLKQRLLRYAASALLFTEKGVDPCLVSWNRIVLLHGPPGTGKTSLCKALAQKLSIRFKSRYSMCQLIEVNAHSLFSKWFSESGKLVAKLFQKIQEMVEEESNLVFVLIDEVESLAAARQAAISGSEPSDSIRVVNALLTQMDKLKSWPNVIILTTSNITTAIDIAFVDRADIKAYVGPPTLQARYEILRSCLQELLRVGILTHTQGGNSLCLLSYFSLMENQHCPEVADPHGSVHLSGLLHKAAEICEGLSGRTLRKLPFLAHASVANPSCCDASAFLHALIQTAQRELSESRG
What is the function of this protein?
Plays a key role in chromosome recombination during meiosis.  Required for the initiation of meiotic recombination and the recruitment of PAIR2 onto meiotic chromosomes.  Essential for meiotic DNA double-strand break (DSB) formation.
What are the official names of this protein?
Pachytene checkpoint protein 2 homolog, Protein CENTRAL REGION COMPONENT 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. PCH2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Appears as punctuate foci on chromosomes at leptotene. Colocalizes with ZEP1 to the central region of the synaptonemal complex.
Protein: RS8_HELAH
Sequence: MVNDIIADSLTRLRNASMRRLEFTQLYYAKIVVSILEIFKEKGFIKDFNIKDKDKKQSVYVQLAYDEKGYSKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVVSTSKGVITNEEAYRQNVGGEVLCSIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PAL4E_HUMAN
Sequence: MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A-like 4E, PPIase A-like 4E.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDK4_RAT
Sequence: MKAARFVMRSASSLGNAGLVPREVELFSRYSPSPLSMKQLLDFGSENACERTSFSFLRQELPVRLANILKEIDILPEHLVNTPSVQLVKSWYIQSLMDLVEFHEKSPEDQKVLSDFVDTLVKVRNRHHNVVPTMAQGILEYKDNCTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSKTGNPSHIGSIDPNCDVVAVVEDAFECAKMLCDQYYLTSPELKLTQVNGKFPGQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENRPFLTPVEATVVLGKEDLTIKISDRGGGVPLRITDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSMSGYGTDAIIYLKALSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSKEPKNLSKEKLAV
What is the function of this protein?
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2.  This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate.  Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism in response to prolonged fasting and starvation.  Plays an important role in maintaining normal blood glucose levels under starvation, and is involved in the insulin signaling cascade.  Via its regulation of pyruvate dehydrogenase activity, plays an important role in maintaining normal blood pH and in preventing the accumulation of ketone bodies under starvation.  In the fed state, mediates cellular responses to glucose levels and to a high-fat diet.  Regulates both fatty acid oxidation and de novo fatty acid biosynthesis.  Plays a role in the generation of reactive oxygen species.  Protects detached epithelial cells against anoikis.  Plays a role in cell proliferation via its role in regulating carbohydrate and fatty acid metabolism.
What are the official names of this protein?
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Pyruvate dehydrogenase kinase isoform 4.
What is the protein family that this protein belongs to?
Belongs to the PDK/BCKDK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: Y1160_ORYSJ
Sequence: MAMNHPLFSQEQPQSWPWGVAMYANFHYHHHYEKEHMFEKPLTPSDVGKLNRLVIPKQHAERYFPLGAGDAADKGLILSFEDEAGAPWRFRYSYWTSSQSYVLTKGWSRYVKEKRLDAGDVVHFERVRGSFGVGDRLFIGCRRRGDAAAAQTPAPPPAVRVAPAAQNAGEQQPWSPMCYSTSGGGSYPTSPANSYAYRRAADHDHGDMHHADESPRDTDSPSFSAGSAPSRRLRLFGVNLDCGPEPEADTTAAATMYGYMHQQSSYAAMSAVPSYWGNS
What are the official names of this protein?
B3 domain-containing protein Os11g0156000.
What are the subcellular locations of this protein?
Nucleus.
Protein: TREA_BEAB2
Sequence: MSDSTAPSAHRPRGSEDFGVFDDAKTYYASDERHTGRFANRTRTYSQSSLIKQIERLNLPEPFRRGSHDESNLEQGRRFLIQVDATLESLKAQEDTDGNMQITIEDSGPKVLPLRTAASAGYHRFEVRGTYMLSNLLQELTLAKEYGRKQIILDEARLNENPVNRLSRLIKDHFWDGLTRRIDASSIEIAARDPKDWTDDPRPRIYIPSKCTAQFEYYKQVALDRPEIRLDVQLLPEVITPEIIRDMNEKPGLLAVAVEEVEEQDPVKGTIKTLRGLPFVVPGGRFNELYGWDSYMESLGLLVNDRVDLAKAMVLNFCFCIEHYGKILNATRSYYLGRSQPPFLTDMALRVYEKIKHEPDALEFLRRSILAAIKEYHSVWTGQARLDPTTGLSRYCPEGLGVPPETEPSHFVHILQPYIKKHGMEFDEFVRAYNHGEIKEPELDNYFMHDRAVRESGHDTSYRFEGVCANLATIDLNSLLFKYETDISRTIRSLFDDKLVMPEEFCQGTPYKPGDILTSALWDRKAKRRKLTMDKLMWNEEEGMFFDYDFVNKKRCTYETATTLWSLWAGLASPKQAADIVKKGLPKFEEFGGLLAGTESSRGEIGLERPNRQWDYPYGWAPQQMLAWTGLLRYSFNEEAERLAYKWLFMITKAFVDFNGVVVEKYDVTRPIDPHRVDAEYGNQGLNFKGVAKEGFGWVNASYVYGLQIVNAHMRRALGTLTPYPTFIKAIEQLNEKALADLE
What is the function of this protein?
Hydrolyzes intracellular trehalose to glucose.
What are the official names of this protein?
Cytosolic neutral trehalase, Alpha,alpha-trehalase, Alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPS2_YEASO
Sequence: MSNGAFDAIFEYAWGQIDKPISGDFIYGKDLPKLIEIIENIFQKAQKSGSYELRLPLFSEINKDLFRTFSNTKTFFKIHKEEFDDIFFNLVNHPLREILENAFIGVDSIPSDFIVSMNLNSPSKFLVENKNKNTEGAGISTPRKKLTESPIKLLSRXNIGKALEVQVEELKRELTAKQSLLQENERQVSELKIRLETYQEKYASIQQRFSDLQKARQVEDNQNSSRTSDPGSPLVTGIDQKAILEEFRRRLQRQTDTISFLKDQIRRERGLNCSNDKVSHSKRKHATTDGDGTFKNFISAVPSNIWVKATIRIIVCFALLAGVLPYIRKYVYAHDTPSQNSRLQLSWWENSGILSKIVWFFEDQTDLETEYRSNANVDDAYSRVFGI
What is the function of this protein?
Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
What are the official names of this protein?
Monopolar spindle protein 2.
What is the protein family that this protein belongs to?
Belongs to the MPS2 family.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: Y2350_DICDI
Sequence: MKSFLNKNKNSKKIIILDDNDFSKYQQRYDLQNQNIEIVSSPLQNIRSQQINDGVQMSGSIQSDLSSSDNFTSSGGFGGGGNSSSNTSNRNSDNSTQRPLMVDIGLEYKYRLALEQNPNDFKALVKWGSLIYKNIKNQMGGKHVDVCLMDWNEELIPIPQNNNNHHNHNHHNNHTSGNFTGNINSNTTLSNSFFETLNSFNLREPLFDVCGKYQSSLQLSGGSNLLNIPFSTLLNYNLNEQLNILVNNLNNSSPSSSSSSIKTKNTTSTTTTTTTTKNLNDISNNINNSRVLRSVSLPPAPPPPPTEDPNSPWSDPILWMKWGDCLFLLCTYLELPMYRATCEKYFKCIQILFKQQEKQHQQQQQQQQNQQDKEKFEKQNNYNIKLLAIVLRKWGITLSRYSRRMKSQFLMSEWTSDENIQVEELWKVLHSQSIQSLLISNKISPSLVTQYHLATAYHRHAITLNQFGCQSKEEIYGLITNSCKIYYETLLESLSDTFLQQLQLQQQQQPWHDIEYYNNNEIFNDQFKSKSLENWGRALDVQLSTKLNDEEETIEKEEEDLNSVDEYLTTFSKSVLKGVTPSLEGVVSLCLNSKQALQYKAINSVSVLCRSSEIVKSPIYNELMDQMTKVESFVSKRDDAESLLSQQKTLKSMPPKLQAYVRMSGLGEEEIMRNFEIAWNSIYFLTKDTIPNQPIPPNYYRSNKKNKLKQRQLNDSNNQDEKEEPEEIKPPLLPSIHRTNQLNNNNNNNNNINNNNINNNNINNNKNGNSGGETPSPSSSFVITPFTSNSQSKFNTQRQFLSNSTLFNLSSSGIFTNNNNNNNGGSTITTTTTNNISPTKTNGWTLTLPSKAPTRRATVSLININDLINQQQQNQINSVSTLSQNNIILNNNNNLDNKPISKYIPNSIIRTTVNPPLLSRCDETIFSSGTPLPLFRDKIKLGTGAFGNVFYAIRKSDSSPVAIKVLMERTKKDSPIIPELYIHSACNHSNIVTYIESYLCKGHVWIILEYCDGGTVRDLLQATCTPGNPNNLQLFEETLIAYIITELLEGLVYLRSKGIIHRDLKSRNILLTRKGKVKIADFGLATTCSLGRGRTRMCGTMGRIAPEVIRREPYDTQSDIYSLGCLIIEMAEGTVPYGKDSSLKALFYTAIHQYKLPNPKKYTKEFVDFLYLCLNPDPFKRPTPEMLLHHTFLSGADRGKSILLGRFKNQDTRKNLLLDNFVAF
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0292350.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: TRPB2_ARCFU
Sequence: MLSWCMKKIMLDESEMPKEWYNVLPDLPEPLPPPLHPATQEPVKPEDLEPIFPKGLIQQEMSGERWIRIPEDVREIYRIWRPTPLVRAERLEKALKTPARIYFKYEGASPPGSHKPNTAVAQAYYNAKEGVERLTTETGAGQWGSALCFATKLFEMACTVYMVKVSFMQKPYRRVMMETWGGEVIPSPSDRTEVGRKILAENPDTPGSLGIAISEAIEDAAKNENTKYSLGSVLNHVLLHQTVIGLETKAQLEKVDEKPDVLIGCVGGGSNFAGLTYPFVNDAKNGDLEIIAVEPAACPTLTAGEYKYDFGDVAGLTPLLKMYTLGHDFIPPPIHAGGLRYHGDAPTLCMLVKHGVIKARAVKQLPTFEAGLLFARTEGIIPAPETNHAVRAAIDEAIKARENNEEKVIVFGFSGHGLLDLQAYDDYLAGRLADT
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: YL8K_SCHPO
Sequence: MSPRASLEKELNSARLLHATINAMDVYTQNLINELQEARDSINDLQRAHERLKLVGAKAKLQIKRDEKKPKS
What are the official names of this protein?
Uncharacterized protein C25B8.20.
Protein: ISPD_ECOSM
Sequence: MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVTRVVIAISPGDSRFAKLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: KATG_ACIBT
Sequence: MSNESKCPFSGHNSKPQVTVGGGTANLHWWPNQLRVDLLNQHSERSNPLGKDFNYRQEFKKLDYYALKADIKNVLTDSQDWWPADWGNYTGLFIRLAWHAAGTYRMGDGRGGAGRGQQRFAPLNSWPDNASLDKARRLLWPVKQKYGQKISWADLFILAGNIALESSGFRTFGFGAGREDVWEPDNDVNWGDEKEWLAHRNSEALAGSNLAATEMGLIYVNPEGPQASGDPRSAAPFIRATFGNMAMDDEEIVALIAGGHTLGKTHGAAPADHVQADPEGAPIEQMGFGWANSYGTGVGKDAITSGLEVIWSQTPTQWSNYFFENLFKYEWVQERSPAGAIQWVAADAEAIIPDPFDPSIKRKPTMLTTDLTLRFDPEFEKISRRFLNDPQAFANAFARAWFKLTHRDMGPKARYLGPEVPAEDLIWQDPLPAASATPSSASIADAKAKIVALGLSAGELVSLAWASASTFRGGDKRGGANGAHIALSPQREWEVNKKAVETLTQIEELKASTQLSLADLIVLAGNVGVEQAAQAAGFNITVPFAPGRVDALQSQTDVESFQLLLGLADGFRNWKKQGVNTPAEVLLIDKAQQLTLTAPELTALIGGLRVLGTNWDGSQHGVFTQQVGVLSTDFFTNLLDMSNVWAPVDSTSEVFEGKDRKSGTVKFTATRNDLVFGSNSILRALAEVYAQADGKEKFVQDFVAAWTKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: YBEY_IDILO
Sequence: MADLTLDYQLADGITKAPEENAVHSWVAATLDYLQENDKAVELTVRIAALEEAQQLNNEFRNKDYATNVLSFPFNSPVELPVTLLGDLVICQSVVEREAEEQQKSAIDHWTHMVIHGTLHLLGYDHIEDDEAEEMEQIERNILASLGISDPYQTADNMELNTQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTE3_ARATH
Sequence: MASGPIAGGGVSKTKHKWSDSGNKSQKRSKPTVANSNSLGLEDNHQMMKISLSSISKLEVRNLKRKLQAELEEVRSLIKRLEPQGNNFAPVPNKKLKTANGGKKGGVHGAAADKGTVQILKSCNNLLTKLMKHKSGWIFNTPVDVVTLGLHDYHNIIKEPMDLGTVKTRLSKSLYKSPLEFAEDVRLTFNNAMLYNPVGHDVYHMAEILLNLFEEKWVPLETQYELLIRKQQPVRDIDFHAPVSTNTHNVEALPLPAPTPSLSPPPPPKVVENRTLERAESMTNPVKPAVLPVVPEKLVEEASANRDLTFDEKRQLSEDLQDLPYDKLEAVVQIIKKRTPELSQQDDEIELDIDSLDLETLWELFRFVTEYKESLSKKKEEQGLDSERDAESFHNSVHESNTLVTGLESSKVTELGHVASTVRQEVNVGGSSSSNSSSSGSGSGSSGSDSDSSGHESDTGN
What is the function of this protein?
Probable transcription factor that binds to acetylated histone H3.
What are the official names of this protein?
Transcription factor GTE3, chloroplastic, Bromodomain-containing protein GTE3, Protein GLOBAL TRANSCRIPTION FACTOR GROUP E3.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CALB1_HUMAN
Sequence: MAESHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELQQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLCEKNKQDLDINNITTYKKNIMALSDGGKLYRTDLALILCAGDN
What is the function of this protein?
Buffers cytosolic calcium.  May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
What are the official names of this protein?
Calbindin, Calbindin D28, D-28K, Vitamin D-dependent calcium-binding protein, avian-type.
What is the protein family that this protein belongs to?
Belongs to the calbindin family.
Protein: ACSA_BRUC2
Sequence: MSEKLYPVLPEAKKNTLIDNETYLEWYEESVSDPDGFWAKHGRRIDWFKPFTKVKNTDFNGDVTIKWYEDGVTNVSYNCIDRHLKSRGDKVAIIWEGDNPYIDKKITYRELYENVCRMANVLKKHGVKKGDRVTIYLPMIPEAAYAMLACARIGAVHSVVFAGFSPEALAGRIVDCESTFVITADEGVRGGKPVALKENTDTAIDIAAKQYVMVNKVLVVRRTGGKVSWGRGRDLWYHQEVASVEPHCEPEPMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYASMTHQYVFDYHDGEIYWCTADVGWVTGHSYIVYGPLANGATTLMFEGVPNFPDQGRFWEVVDKHHVNIFYTAPTALRALMGAGDEFVTRSSRSTLRLLGSVGEPINPEAWEWYYNVVGDQKCPIVDTWWQTENGGILITPLPGATDLKPGSATRPFFGVKPVLVDNEGNVQEGVADGNLCISDSWPGQMRTVYGDHKRFIETYFSTYKGMYFSGDGCRRDEDGYYWITGRVDDVLNISGHRLGTAEIESALVSHHSVSEAAVVGYPHPIKGQGIYCYVTLMTGADAQDPDELRKELVQHVRKEIGPIATPDKIQFAPGLPKTRSGKIMRRILRKIAEDEFGALGDTSTLADPGVVDDLIENRQNKK
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: SECB_EDWI9
Sequence: MSEQNNTEMSFQIQRIYTKDISFEAPNAPAVFQKEWQPEVKLDLDTASNQLADGVFEVVLRVTVTATMGEETAFLCEVQQAGIFTIAGIDGTQMAHCLGAYCPNILFPYARECITNLVARGTFPQLNLAPVNFDALFMSYLQQQAGEEPTQEA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPSA_MAIZE
Sequence: MAGNEWINGYLEAILDSHTSSRGAGGGGGGGDPRSPTKAASPRGAHMNFNPSHYFVEEVVKGVDESDLHRTWIKVVATRNARERSTRLENMCWRIWHLARKKKQLELEGIQRISARRKEQEQVRREATEDLAEDLSEGEKGDTIGELAPVETTKKKFQRNFSDLTVWSDDNKEKKLYIVLISVHGLVRGENMELGRDSDTGGQVKYVVELARAMSMMPGVYRVDLFTRQVSSPDVDWSYGEPTEMLCAGSNDGEGMGESGGAYIVRIPCGPRDKYLKKEALWPYLQEFVDGALAHILNMSKALGEQVGNGRPVLPYVIHGHYADAGDVAALLSGALNVPMVLTGHSLGRNKLEQLLKQGRMSKEEIDSTYKIMRRIEGEELALDASELVITSTRQEIDEQWGLYDGFDVKLEKVLRARARRGVSCHGRYMPRMVVIPPGMDFSNVVVHEDIDGDGDVKDDIVGLEGASPKSMPPIWAEVMRFLTNPHKPMILALSRPDPKKNITTLVKAFGECRPLRELANLTLIMGNRDDIDDMSAGNASVLTTVLKLIDKYDLYGSVAFPKHHNQADVPEIYRLAAKMKGVFINPALVEPFGLTLIEAAAHGLPIVATKNGGPVDITNALNNGLLVDPHDQNAIADALLKLVADKNLWQECRRNGLRNIHLYSWPEHCRTYLTRVAGCRLRNPRWLKDTPADAGADEEEFLEDSMDAQDLSLRLSIDGEKSSLNTNDPLWFDPQDQVQKIMNNIKQSSALPPSMSSVAAEGTGSTMNKYPLLRRRRRLFVIAVDCYQDDGRASKKMLQVIQEVFRAVRSDSQMFKISGFTLSTAMPLSETLQLLQLGKIPATDFDALICGSGSEVYYPGTANCMDAEGKLRPDQDYLMHISHRWSHDGARQTIAKLMGAQDGSGDAVEQDVASSNAHCVAFLIKDPQKVKTVDEMRERLRMRGLRCHIMYCRNSTRLQVVPLLASRSQALRYLSVRWGVSVGNMYLITGEHGDTDLEEMLSGLHKTVIVRGVTEKGSEALVRSPGSYKRDDVVPSETPLAAYTTGELKADEIMRALKQVSKTSSGM
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate (PubMed:1840396).  Involved in the regulation of carbon partitioning in the leaves of plants (PubMed:1840396).  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf (PubMed:1840396).  Plays a role for sucrose availability that is essential for plant growth and fiber elongation (PubMed:1840396).
What are the official names of this protein?
Sucrose-phosphate synthase, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: RL35_SHIDS
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: ARNA_ENT38
Sequence: MKAVVFAYHDIGCAGINALVAAGYDITAIYTHPDAPSENHFFGSVARTAAEHGIPVYAPNDVNHPLWIDRIKSAQPDVIFSFYYRNLLCDEILNSATVGAFNLHGSLLPHYRGRAPLNWVLVKGETETGVTLHKMVSRADAGAIVAQHRVAIAPEETALTLHHKLTQASSDLLKDILPVIKTGHFPEVEQDHSQASIFGRRTAQDGCIDWHATAQEISNLVRAVTDPWPGAFGYVGGSKFIVWKARALEGLQAAKAGTVLSVSPLVIATGGGALEIMTGQTENGVYMQGSQLAQTLGLVAGAIISSQPVSAIKRRTRVLILGVNGFIGNHLTERLLQDDNFEVYGLDIGSDAISRFIGNSRFHFVEGDISIHSEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKIIRDCVKYQKRIIFPSTSEVYGMCSDKVFDEDHSNLIVGPINKQRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGRQKRCFTDISDGIEALFRIIENKNSNCDGQIINIGNPDNEASIKELAEMLLASFEKHPLRNHFPPFAGFREVESSTYYGKGYQDVEHRKPSIRNAHRLISWTPTVEMEKTIDETLDFFLKTVELTEPQA
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: PURA_SHEAM
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEQAKYVVRYQGGHNAGHTLVIDGVKTVLHLIPSGILRDNVKCIIGNGVVLAPDALMKEISMLKERGVPVEDRLLISEACPLILPFHCAVDIAREKARGNKAIGTTGRGIGPAYEDKVSRRGLRVGDLFNAELFAEKLKEVMKYHNFMLTEYYGAEAVDYQTTLDDALAMADYLKSMCVDVTEMLDQARKAGENILFEGAQGTLLDIDHGTYPFVTSSNTTAGGVATGSGFGPCHLDYVLGIMKAYTTRVGAGPFPTELECEIGDHLGTKGHEFGATTGRKRRPGWLDAVAMKRAIQINSLTGICLTKLDVLDGLEEVKICVGYQQPDGTVTTVTPLAAEGYELVTPVYETLPGWSENTFGVTSMDQLPQAAVNYIKRIEEILETPIDIISTGPDRNETFIRVSPFN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_CORGL
Sequence: MIDLKFLRDNPDVVRASQITRGEDPALVDELISADESRREAIKAADDLRAEQKAFGKKIGQASPEDRPALLEGSNELKAKVKDAEAAQEAAEAKVNELQMKLSNVVSGAPAGGEDDFVVLETIGEPRTFDFEPKDHLELGESLGLIDMKRGTKVSGARFYYLTGDGAMLQLGMLMLAAQKAREAGFSMMIPPVLVRPEIMAGTGFLGDHSEEIYYLERDDMYLVGTSEVALAGYHKDEIIDLNEGPVKYAGWSSCFRREAGSYGKDTRGILRVHQFDKVEMFVYCKPEDAEDVHQQLLGMEKEMLAAIEVPYRVIDVAGGDLGASAARKFDTEAWVPTQDTYRELTSTSNCTTFQARRLQTRYRDENGKPQIAATLNGTLATTRWLVAILENNQQADGSVVVPEALRPFVGKDVLKPVKQAG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_MYCA9
Sequence: MIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDIIVATVKDAIPGGTVKRGDVVKAVVVRTVKERRRPDGSYIKFDENAAVIIKADNDPRGTRIFGPVGRELRDKKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: THIM_ECOHS
Sequence: MQVDLLGSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDPVAVGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEMDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: TYSY_STRP7
Sequence: MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAFSEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDTGTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBA1_ORYSJ
Sequence: MREIISIHIGQAGIQVGNACWELYCLEHGIEPDGTMPSDTTVGVAHDAFNTFFSETGAGKHVPRAIFVDLEPTVIDEVRTGSYRQLFHPEQLISGKEDAANNFARGHYTVGKEIVDLCLDRVRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPQVSTAVVEPYNSVLSTHSLLEHTDVAVLLDNEAIYDICRRSLDIERPTYTNLNRLISQIISSLTTSLRFDGAINVDVTEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVPEITNAVFEPSSMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTVQFVDWCPTGFKCGINYQPPSVVPGGDLAKVQRAVCMISNNTAVAEVFSRIDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAEGADDENDDGEDY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.