PharMolix/UniProtQA huggingface dataset:
Protein: APC15_MOUSE
Sequence: MEPGLKLSLGAMSTLFPSLFPRVTETLWFNLDRPCVEETELQQQEQQHQAWLQSIAEKDNNLVPIGKPASEHYDDEEEEDDEDDEDSEEDSEDDEDMQDMDEMNDYNESPDDGEVNEVDMEGNEQDQDQWMI
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  In the complex, plays a role in the release of the mitotic checkpoint complex (MCC) from the APC/C: not required for APC/C activity itself, but promotes the turnover of CDC20 and MCC on the APC/C, thereby participating in the responsiveness of the spindle assembly checkpoint.  Also required for degradation of CDC20 (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 15, APC15.
What is the protein family that this protein belongs to?
Belongs to the APC15 family.
Protein: NODC_RHISM
Sequence: GSARVSACVASIAKQDYAGELRVYVVDDGSGNRNAIIPVHDHYACDPRFRFILMPKNVGKRKASIVAIGKSSGDLVLNVDSDTTMRRRVASKLASKSRIREDAPTILMRNAGFRTEYVPEAIAETVVPNSMNAYLRQQRRWARSSFADTLAVLLLLGLDRYLTLDEIGGNLGPLLLALSVVSGLAQLALTATVPWS
What is the function of this protein?
Involved in the synthesis of Nod factor, a sulfated N-acyl-beta-1,4-tetrasaccharide of N-acetylglucosamine which initiates a series of events in the host plant species leading eventually to nodulation.
What are the official names of this protein?
N-acetylglucosaminyltransferase, Nodulation protein C.
What is the protein family that this protein belongs to?
Belongs to the NodC/HAS family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YHFT_BACSU
Sequence: MTITHTYSSTAETSPGRVAIQTESEQITYHDWDRLVSQTANWLRSQPSMPNRVAILLPNSLAFLQLFAGAAAAGCTAIPIDTRWSPAECKERLSISNADLVVTLAFFKNKLTDSQTPVVLLDNCMADISEAAADPLPTIDPEHPFYMGFTSGSTGKPKAFTRSHRSWMESFTCTETDFSISSDDKVLIPGALMSSHFLYGAVSTLFLGGTVCLLKKFSPAKAKEWLCRESISVLYTVPTMTDALARIEGFPDSPVKIISSGADWPAESKKKLAAAWPHLKLYDFYGTSELSFVTFSSPEDSKRKPHSAGRPFHNVRIEIRNAGGERCQPGEIGKIFVKSPMRFSGYVNGSTPDEWMTVDDMGYVDEEGFLYISGRENGMIVYGGLNIFPEEIERVLLACPEVESAAVVGIPDEYWGEIAVAVILGNANARTLKAWCKQKLASYKIPKKWVFADSLPETSSGKIARSRVKKWLEESVQYK
What is the function of this protein?
May be involved in fatty acid metabolism.
What are the official names of this protein?
Uncharacterized acyl--CoA ligase YhfT.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: EDF1_HUMAN
Sequence: MAESDWDTVTVLRKKGPTAAQAKSKQAILAAQRRGEDVETSKKWAAGQNKQHSITKNTAKLDRETEELHHDRVTLEVGKVIQQGRQSKGLTQKDLATKINEKPQVIADYESGRAIPNNQVLGKIERAIGLKLRGKDIGKPIEKGPRAK
What is the function of this protein?
Transcriptional coactivator stimulating NR5A1 and ligand-dependent NR1H3/LXRA and PPARG transcriptional activities.  Enhances the DNA-binding activity of ATF1, ATF2, CREB1 and NR5A1.  Regulates nitric oxid synthase activity probably by sequestering calmodulin in the cytoplasm.  May function in endothelial cells differentiation, hormone-induced cardiomyocytes hypertrophy and lipid metabolism.
What are the official names of this protein?
Endothelial differentiation-related factor 1, EDF-1, Multiprotein-bridging factor 1, MBF1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Also nuclear upon binding to NR5A1 and treatment of cells with TPA or forskolin.
Protein: OTC_CLOB1
Sequence: MFNLKNRNFLTLMDFTPKEINYFLDLARDLKRAKYTGTEVQRLKGKNIALIFEKASTRTRCAFEVGAKDQGAHVTYLGPTGSHIGKKESAADTARVLGRMYDGIEYRGFGQEIVETLAEYAGVPVWNGLTDEDHPTQILADFLTIREHFNKPLNEIKFAYVGDGANNMANALMIGAVKMGMDFRIVSPKEIPTDAALVAKCKEIAAETGAKVTITDNIEEGVKGCDVLYTDVWVSMGEPDSVWESKIKLLTPYRVDMNMIKMTGNPDAKFMHCLPAFHDEETAVGKEIKEKYGLSEMEVSHELFESKYSIVFDEAENRMHTIKAVMVATLGDQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_LACAC
Sequence: MAETKDQNVLNIIIISDAAGDTAFSNATAAAAEFPNAEINYRRYPFITNLEKLDEVLKEIEKYPNLVIIFSLVKDEMQIPVIKFARDHNIQCVDIFSPVVEAIQQTTHMIPDQKIGAQHSLNQKYFDRISAMEFAVMYDDGKDPKGFLEADVVLLGVSRTSKTPLSLFLANKNLKVANLPLVPETHIPKEIYEIDPKKIIGLTNDPSVLNEIRRQRMIAYGLNPDTTYSSMDSINKELESAQALYKKLGCYVINVAHRSIEETAALILEHLGIDDYAK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RSMJ_RHOP2
Sequence: MAAAGRSALAIDFVGGAVGYKLRSGAARSHALLKATGMAPGRALQVIDATAGLGRDAFLLASMGASVTLIERSPQVHALLAQGLAAAQAESAELAGVVARMTLIQGDARDLLPTLQADVVTVDPMHPERTKTALVKQEMRLLRDLVGADPDVCELMQAALSARCGRVVLKWPLRAEPLAGVRKPSYQIAGKTVRYDVFVLPRGAAEERAPGADAALNP
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEBB_STENO
Sequence: MSKGASAPQQQSAFKQLYTELFNNEGDFSKVSSNLKKPLKCYVKESYPHFLVTDGYFFVAPYFTKEAVNEFHAKFPNVNIVDLTDKVIVINNWSLELRRVNSAEVFTSYANLEARLIVHSFKPNLQERLNPTRYPVNLFRDDEFKTTIQHFRHTALQAAINKTVKGDNLVDISKVADAAGKKGKVDAGIVKASASKGDEFSDFSFKEGNTATLKIADIFVQEKGKDALNKAADHTDGAKVKGGAKGKGKAAAKAAKGKKLSAKKGDSSAADVRKSVDKIVKYTPSKGSRKDTPQKSQAPAAGKSSAKKGGKKAVPSAPSPSGKKSALTTDKMTMAQFVKYLDWHEKKKGGKVSSGGKVLGKRSAGKASATSGKASKASKKTAAKK
What is the function of this protein?
May function as protective capping of the single-stranded telomeric overhang.  May also participate in telomere length regulation during DNA replication.  Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
What are the official names of this protein?
Telomere-binding protein subunit beta, TEBP beta, Telomere-binding protein 41 kDa subunit.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: FOXB1_MOUSE
Sequence: MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQYLQQQAKLRLSALAASGTHLPQMPAAAYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQPVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMTSGDYSAYGVPLKPLCHAAGQTLPAIPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALHSVAVH
What is the function of this protein?
Transcription factor expressed by neural progenitor cells in specific regions of the embryonic neuroepithelium (PubMed:28725186, PubMed:15654859).  Essential for the mammillary nuclei maintenance (PubMed:15654859).  Negatively regulates the proliferation of oligodendrocyte progenitors and promotes oligodendrocyte maturation (PubMed:28725186).  Also expressed in mammary glands, plays a role in lactation, controls development of mammary glands and the inferior colliculi of the midbrain in the central nervous system that regulates the milk-ejection reflex (PubMed:11170346).
What are the official names of this protein?
Forkhead box protein B1, Transcription factor FKH-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB5_PIG
Sequence: MAEQSDKAVKYYTLEEIQKHNNSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATENFEDVGHSTDARELSKTFIIGELHPDDRSKIAKPSETLITTVESNSSWWTNWVIPAISALVVSLMYHFYTSEN
What is the function of this protein?
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
What are the official names of this protein?
Cytochrome b5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: MAGE2_HUMAN
Sequence: MSLVSQNARHCSAEITADYGDGRGEIQATNASGSPTSMLVVDAPQCPQAPINSQCVNTSQAVQDPNDLEVLIDEQSRRLGALRVHDPLEDRSIALVNFMRMKSQTEGSIQQSEMLEFLREYSDQFPEILRRASAHLDQVFGLNLRVIDPQADTYNLVSKRGFQITDRIAESLDMPKASLLALVLGHILLNGNRAREASIWDLLLKVDMWDKPQRINNLFGNTRNLLTTDFVCMRFLEYWPVYGTNPLEFEFLWGSRAHREITKMEALKFVSDAHDEEPWSWPEEYNKALEGDKTKERSLTAGLEFWSEDTMNDKANDLVQLAISVTEEMLPIHQDELLAHTGKEFEDVFPNILNRATLILDMFYGLSLIEVDTSEHIYLLVQQPESEEEQVMLESLGRPTQEYVMPILGLIFLMGNRVKEANVWNLLRRFSVDVGRKHSITRKLMRQRYLECRPLSYSNPVEYELLWGPRAHHETIKMKVLEYMARLYRKRPQNWPEQYREAVEDEEARAKSEATIMFFLDPT
What are the official names of this protein?
Melanoma-associated antigen E2, Hepatocellular carcinoma-associated protein 3, MAGE-E2 antigen.
Protein: PANC_SHEDO
Sequence: MITSSDVSTIRAQVRSWRSQGESVAFVPTMGNLHQGHITLVKEAKLRAKHVVVSIFVNPMQFGQHEDLDAYPRTLAADSQALIDAGAALLFTPTAQTIYPKGLQQQTFVEVPEIGDVFCGASRPGHFRGVATIVCKLFNIVQPDIALFGRKDFQQLLVIKHMVNDLSLGIDIIGIDTIREASGLAMSSRNGYLTPEQKHTAATIKRALDLIANAVRQGEAIDKATAEGEAMIVQAGFKLDYLSVCNADNLHPAQADDKQLVILVAAYLGTTRLIDNLCFSR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPA_PSEP1
Sequence: MRLERALRARQLIPLAAIWLLVGCGKQETVESTAVPPEVGVYTVKAQALTLTTDLPGRTSAYRVSEVRPQASGILQKRMFVEGAEVKQGEQLYQIDPRTYEALLARAEASLLTAQNLARRYERLLDTNAISQQQYDDAMATWKQAQAEAQMARINMQYTKVLAPITGRIGRSAVTEGALVTNGQAQELATVTQLDPIYVDVNQPITRLLGLKRALESGRLQRVGDNQAQVSLTLDDGTPYPLKGVLKFSEVSVAPSTGSVTLRAEFPNPDHKLLPGMFVHALLNEGEQQAAILVPHQAVGRDARGVPTVWVVKPDNTVESREVQTLQTVGNAWLLGAGINDGERVITEGVQLARSGITVKPVAAKNVKLMSEFGSQVQAQAH
What is the function of this protein?
Probable periplasmic linker protein component of the SepABC efflux pump with unknown specificity.
What are the official names of this protein?
Probable efflux pump periplasmic linker protein SepA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: RS15_SHISS
Sequence: MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: MIRD_ASPFU
Sequence: MLSSWQKKFFQTPEHPPAEGIAPPRDDGVPNPEPVTYPDTKYPSDVVNHDAGEMLPNEEAQDGVTQAEAITLTWSKISLGAAYFLMWLLYLVNGFQASITGNLSAYVTSGFESHSLIPVISIVSSVMSAATYMPLAKVLNLWDRSIGFIIMVAFATLGLILSATCHDIGTYCAAQVFYSIGFAGIIFSVDVITADTSTLRDRGLAYAFTSSPYIITAFGGPAAAEHFYDSNWRWAYGCFSIVLPVVALPMFCLLRWNRHKAKKSGLLKDKADSGRTWMESIRHYIIEFDILGVFFLAAGLVLFLLPFSIAGSTEDDWKSASIITMLVIGFVCLLVFALVERFVAPVPFLPWALLASRTVLGACMLDVCYQIAYYCWFNYYTSYLQVVYGTSITTAGYITSIFDVVSGVWLFIVGFLIKKTNRFRWLLFIAVPLYILGVGLMIYFRKPSWSVGYMIMCQIFIAFAGGTMIICQQVAVLAASDHDHAASSLAFLNVFGTMGSAVGSSISGAIWTHTLPGALQRLLPDSVKADWQTIYDSLEEQLSYERGTLIRQAIALAYASTQSKMLIAGTAIMALSLVWMFVIRDIKLTKTQTKGVLF
What is the function of this protein?
Major facilitator transporter involved in fusarinine C (FsC) uptake (PubMed:36125294).  In contrast to TAFC-mediated iron uptake, FsC-mediated iron uptake via mirD does not play a significant role during infection (PubMed:36125294).
What are the official names of this protein?
MFS siderochrome iron transporter D.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
Protein: RAG1_KLULA
Sequence: MSNQMTDSTSAGSGTEHSVDTNTALKAGSPNDLKVSHEEDLNDLEKTAEETLQQKPAKEYIFVSLCCVMVAFGGFVFGWDTGTISGFVNQTDFLRRFGQEKADGSHYLSNVRTGLIVSIFNIGCAVGGIVLSNIGDRWGRRIGLITVIIIYVIGIIIQIASVDKWYQYFIGRIISGLGVGGITVLSPMLISETAPKHLRGTLVSCYQLMITFGIFLGYCTNYGTKNYSNSVQWRVPLGLCFAWAIFMVLGMMFVPESARFLVETDQIEEARKSLAKTNKVSIDDPVVKYELLKIQSSIELEKAAGNASWGELITGKPSMFRRTLMGIMIQSLQQLTGDNYFFYYGTTIFQSVGMDDSFETSIVLGIVNFASTFFALYTVDHFGRRNCLLYGCVGMVACYVVYASVGVTRLWPDGPDHPDISSKGAGNCMIVFACFYIFCFATTWAPIAYVVISESYPLRVKGKAMAIASASNWIWGFLIGFFTPFITSAIHFYYGYVFMGCMVFAFFYVYFFVPETKGLTLEEVNEMYSEGVLPWKSSSWVPSSRRGAEYDVDALQHDDKPWYKAML
What is the function of this protein?
Low-affinity glucose transporter.
What are the official names of this protein?
Low-affinity glucose transporter, Hexose transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: G6PI_ECOHS
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFGDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_ANGIN
Sequence: MANLRKTHPLLKIANDALVDLPTPSNISAWWNFGSLLGLCLISQIITGLFLAMHYTSDISTAFSSVAHICRDVNYGWLIRNLHANGASFFFICLYLHIARGLYYGSYLYKETWNIGVVLFLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGDSLVQWIWGGFSVDNATLTRFFAFHFLFPFVVAGATMIHLLFLHETGSNNPVGLNSDADKIPFHPYFSYKDLLGFIIMLTALTMLALFYPNLLGDPDNFTPANPMVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLSSILVLMVVPILHTSKQRGLTFRPASQLLFWILVADMLVLTWIGGMPVEHPYIIIGQVASVLYFSLFLVLNPLVGWLENKMMNW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RR14_POPAL
Sequence: MARKSLIQREKKRQKLEQKYHLIRRSSKKEISKVPSLSDKWEIHGKLQSPPRNSAPTRLHRRCFLTGRPRANYRDFGLSGHILRAKVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS8_PSEPF
Sequence: MSMQDPLADMLTRIRNAQMAEKSVVSMPSSTLKVAVAKVLKDEGYIAGYQISSETKPLLSIELKYFEGRPVIEEVKRVSRPGLRQYKSVEELPKVRGGLGVSIVSTNKGVMTDRAARAAGVGGEVLCTVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: HIS2_STRGC
Sequence: MLETLYQEALKRKKEPKEGSYTSYLYDKGLDKILKKVGEEATEVVIAAKNDDKNEMANETADLLYHMAVALVETGVSLEEVEAVLQARQGKQSRIHDRPEIDQY
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AKH2_ARATH
Sequence: MATLKPSFTVSPPNSNPIRFGSFPPQCFLRVPKPRRLILPRFRKTTGGGGGLIRCELPDFHLSATATTVSGVSTVNLVDQVQIPKGEMWSVHKFGGTCVGNSQRIRNVAEVIINDNSERKLVVVSAMSKVTDMMYDLIRKAQSRDDSYLSALEAVLEKHRLTARDLLDGDDLASFLSHLHNDISNLKAMLRAIYIAGHASESFSDFVAGHGELWSAQMLSYVVRKTGLECKWMDTRDVLIVNPTSSNQVDPDFGESEKRLDKWFSLNPSKIIIATGFIASTPQNIPTTLKRDGSDFSAAIMGALLRARQVTIWTDVDGVYSADPRKVNEAVILQTLSYQEAWEMSYFGANVLHPRTIIPVMRYNIPIVIRNIFNLSAPGTIICQPPEDDYDLKLTTPVKGFATIDNLALINVEGTGMAGVPGTASDIFGCVKDVGANVIMISQASSEHSVCFAVPEKEVNAVSEALRSRFSEALQAGRLSQIEVIPNCSILAAVGQKMASTPGVSCTLFSALAKANINVRAISQGCSEYNVTVVIKREDSVKALRAVHSRFFLSRTTLAMGIVGPGLIGATLLDQLRDQAAVLKQEFNIDLRVLGITGSKKMLLSDIGIDLSRWRELLNEKGTEADLDKFTQQVHGNHFIPNSVVVDCTADSAIASRYYDWLRKGIHVITPNKKANSGPLDQYLKLRDLQRKSYTHYFYEATVGAGLPIISTLRGLLETGDKILRIEGICSGTLSYLFNNFVGDRSFSEVVTEAKNAGFTEPDPRDDLSGTDVARKVIILARESGLKLDLADLPIRSLVPEPLKGCTSVEEFMEKLPQYDGDLAKERLDAENSGEVLRYVGVVDAVNQKGTVELRRYKKEHPFAQLAGSDNIIAFTTTRYKDHPLIVRGPGAGAQVTAGGIFSDILRLASYLGAPS
What are the official names of this protein?
Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic, AK-HD 2, AK-HSDH 2, Beta-aspartyl phosphate homoserine 2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the homoserine dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PIF3_TRYB2
Sequence: MRLAAESSLVFFVSHFYFERFFSFVMVAYTLDTLFASDIDSATLFYSEGCGPIRLVALSAQMRRLVRLGPIRVAKACVEVRPMAPTKEFFEEGRQLQHIEAAGVGDFPDSERSGDTFVNPFTGRLTPTWGRVAKELFSLGFEHSIVNPFRLVWNPTKAALVSDAALQPFRTSTVTWRRNLAALLSRRDAADAVGEEIHRLYNEITSAYLPPKLDTMHDPRLSTMTMTPDQQNVIRCALRGYSMFIGGSAGTGKTVLLKAIHRKLTEMGLRVAMTATTGVASVQLGGCTFHLAFGVPIKGEEGTRKRWDSNAFRAVDVVIIDEVSLLDAELFETFEEEARMARLQQSPFGGLQVIACGDFLQLAMMDVSIGGPCYQSHAFRHLIPVCLVTSMRQAQGDPFCELLGQLRVGKFDKKAFKALDRPVSGDANNVTYIFPRRCDAQRLNDEKLCELRSEEMIFAPQRGPLQLVGNFTPAGLVDWGRKKDFPKREKIITVLSEEIKRITGVDIVDHNIVVMPAGGEKNAVLIRLRHSEDRNVLICKNGGSKEHGASNEGGAEESHWRAILEATAGRLKGKLHQIYNQDPHNFIPPSVSLMLADASLHPNAELISPLRLKLGCRVMINRNLSRTVSNGSVGIVEAFAAPNLDLFPRRHETSPKAFHTWSLERNGFQRLPIVRLLSGEVVQLPPLSVMIGGTPSTYFYGHELFVLPLQLGYGFTVHKVQGLTLEGTVVLDCKKFFECPHLVYVACSRVRSMDQLIVRNVRSDMIIVRQSALDFTNALRDASVMSSLDPPDGCTRASWVRRLSPLLVGLTD
What is the function of this protein?
DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of genome stability.
What are the official names of this protein?
ATP-dependent DNA helicase PIF3, DNA repair and recombination helicase PIF3.
What is the protein family that this protein belongs to?
Belongs to the helicase family. PIF1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL12A_PAPAN
Sequence: MCPARSLLLVATLVLLDYLSLARNLSVATPGPEMFPCLHHSQNLLKAASNTLQKARQILEFYPCTSEEIDHEDITKDKTSTVEACLPLELIKNESCLNSRETSVITKGSCLASRKTSFMMALCLRSIYEDLQIYQVEFKTMNAKLLMDPKRQIFLDQNILGVIDELMQALNFNSETVPQKSSLEEPDFYKTKIRLCILLHAFRIRAVTIDRVMSYLNAS
What is the function of this protein?
Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine.  IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity.  Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits.  Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2.  In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity).  As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity).  Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers.  Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
What are the official names of this protein?
Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_LISMO
Sequence: MIVIIDYDTGNTKSISKALDFIGLQNKISSDATEISQADGVILPGVGAYPEAMKELTRRGLNKTLKEIAAGGKPILGVCLGMQLLLESSNEHSFTNGLGLIPGHVEKLPEDPEFAVPHMGWNQLQIKRATPLTKQLDGEYVYYVHSYYANCPEEYIIATSGYSIEVPGMINKGNIYGAQFHPEKSGQIGLEILKGFKEVTYSCKSSQQ
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_VEREI
Sequence: MQIILLDKVVNLGNLGQIVKVKDGYARNFLIPTGRARRATEAAKAEFEAKRAELEKTAATNLAQAQAQGEKLAGTAIKLTQKAGVDGRLFGSVTNHDIAEELNKQGFKLAKSRIRLPNGPIKMVGDNTVSVVLHTDVVVEVIVSVYGETA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RL20_ANAMM
Sequence: MARVKRGVTARARHKKVVALAKGYRGRSKNCYRAALQRLEKALVYAYRDRRNRKRDFRRLWIVRINAAARQWGIKYSQLMKGMALCGIELNRKMLAEMAVNDKAAFEKVVSAVAGTCGYACAVNQQDK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RNP1_CAEEL
Sequence: MPSKLFVGNLPDNVDSNKLKQVFQPFCKVTECDIVKNYAFVHIEEDDVDPIITRLTGYTIDGKVVNIKKSTSKLRPTPGMPNRCFRCQSDEHRTPQCPQDPTNNQKTENGVQTLKFDLTSGAGVKRSAGDPIIDSAKRIAYGAQSVVEPEIPQPMDPDLQALYQEYQLSRQRYVYYRDRLLKEMEAKQHGSTAGFALSSSSTVPVPVASAPPGATQLSAAPVSYQPNAPPVIASINAPYAVASNLRAPYALQSAPYASAASAPYGSVTPAGAPSNVMTTQQYLQQIQHQQATGSPAPVPAPPRLY
What is the function of this protein?
RNA-binding protein that is required for the germ line to transition from spermatogenesis to oogenesis and allow for normal oocyte development.
What are the official names of this protein?
RNA-binding protein rnp-1.