PharMolix/UniProtQA huggingface dataset:
Protein: SYE_METM6
Sequence: MKDTVMAYLLENSIKFKGKPNPKAAMGKILGENPDLRSKVKEVNEVISEVLKEIETMSLEEQQAKLDELAPEGLGQKTERKRKEIELKNVKGNVAMRFAPNPSGPLHIGHARASVLNDFFTKKYNGKLVLRLEDTDAKRVLPEAYEMIQEDLNWLGVKVDEVIVQSERLEIYYEYGRKLIEMGHAYVCDCDAEEFRNLREQGIPCKCRDATPEENIVLWEKMLSGEVENVAVRLKTDIAHKNPSIRDFPIFRIERTPHPKNGTKYHVYPLMNLSVTVDDHLLGMTHVLRGKDHIVNTEKQEYIYNYFGWEIPEYIHYGILKIEGPVLSTSKMHAGILSGEYSGWDDARLGTLRALRKRGIRPEALYKLMVEIGIKQADVRFAWENLYAANKDVIDKDARRFFFVESPKKVVISGAENKKIDLRMHPDRSELGNRELLFDGEIYVSDDLEAGKMYRLMELFNIVVERIENDIIYAKYDSDDLAVAKSNRASIIHWIPVKDSIPVTVIDENAENIEGFAEKDFAVVKKDDFVQFERFGFVRVDEKEDNGYICYLTHK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_STRA3
Sequence: MNNQLIYTGKAKDIYSTKDENVIRTVYKDQATMLNGARKETIDGKGALNNQISSLIFEKLNMAGVVTHYIEQISKNEQLNKKVDIIPLEVVLRNVTAGSFSKRFGVEEGRVLETPIVEFYYKNDDLNDPFINDEHMKFLGIVNDEEIAYLKGETRRINELLKDWFAQIGLNLIDFKLEFGFDKDGKIILADEFSPDNCRLWDAEGNHMDKDVFRRDLGSLTDVYQVVLEKLIAL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: IML1_USTMA
Sequence: MAPQFASSRATSLSVDRFSTASDRRHSSSSSTHQQRPQINERPITLWTHDPPNFSRNEVVLNPEYSLPRLAESDLLQLTLPAGSRLPHNSIPFGPKDRRCKFSTKATFVFRAAQATADADFVARQPQLQISVSKNIANNYGFYNRAEAILTRVTKDDFTIDHVELYFRDQYVGRAEMWRVFQNLEDTCVYCGQKVTLAGSVRATIGRIFIKEKKVTSGYVSASTKAIFRSESAKYNLFIQLSREMWEFDEDGEIYYEKALQGFIPELLRRWRAVPTNHILTVILFARVHYDESEIHMLEGPIRQDARGKYYIDYYKVVVDLESNCNWDAVMTTLKEEFFRFQHDILLIRRPISGPAASHEELHADLIRDRVHMAGRISSSYEGNLLEAINLALNPFDEHYIDRDLNRTGLSMVFLTAGTGHFDVDKKLLRITTERMIENGTGLDLVCLTKMPLHSVPLFHFKSHYPDPSELKQSQAAAHNRSQRRTGPGAGPGMTVHRPGQPALLSRHSSSRLAAVNSTPANPPDPLYFDSRKPVEEEDDFYSMPHWIDCSFYNLQQDKPFRADRFVPRCKMYDVQMMGFMENQISDIAIPYLDLKPVNKASSLHSSFYLPRHVGPSSSGFHSEPRNSEVSDLALVGLSPKQQRRIARERFDADVFRNVSPYLKPNPYRLLNAAAGTSGFIDSPVTSDMHRPGLRRNPSSGYGGIPTTNANSAASSISPGKAGASRPPVQQTRLSKLGREASLREDEADQDASAPPSPEKPRFNVLDEPLARPPLARPISHIVTSTTKPKSRAGSIRSVNTFSRGFMPMEPIGKAMAIVASTDALLSATSHTFDEQELDAAAAKQYNEADDSVSSLRSPAQLKAKGYSWLWKTLTGSTSSRSASSERSGDFDGGQGAKDFSTPATRSMQEVLSAQLRQQAGGSSKPTSPARRPPIPGRMSRTSSLLSVHEASSPAPIKIPAQQTPRSRQELETEAKLLRDQEAYEQQLEEEEARQRYAQRAQVEKQTLVNPSNPSKNLKGAATQLLRWQHLFPRRLNHHAVKWRSMTTPACLPLTTLYLPTESDLAAMWSEHPHTTSISAETASFLLKKSSSTHPALAVLREMAYHRLAQGYQFIVPASKQTRAVSSRKLVDPKHFTLRWPSELLQPGNLATGNPIFLSVTNQIHRISYDRSTSAINVKRYVRNTNYSTDPIDYECCIWPRHLPGYQTVKARFVYPDSASYNWTYLDSLIAGYVDEKFVESLRYWRTRFVLVPSEGSPPPMRAPTGEDLNDEEIRLIGTDKLAELFHRARFVRSKEEREQTHVQRFLPTSLDPAMSLQDDDFMKQLAEENAKQRAQSASSKKRLNKTISGRALEAVSRDMRSGGLVINDRIWHRMLYSDTFTGADMVSWMCIEYTDVRSREEAVDWGIRLMQDGLFEHVHKSHGFLDGHYFYRLKSEYAGTRGPKGWFRGTDSQRGSFAEKESLSRPLVHSSGQYAGSNTGETRGVSGGEVVSEKNAVAVAGTTSTSSRSSAGRHSRSSSLHLAHPPSLTMSSSHTAGGGGGKKKKKVQLSRSLVIDVDPGRRSDRAEVAFLHHDIAHNPANGFNFQIHWLSTSARFIEDAVQSWTRTLERYGLRLIEAPIGQIKDVSLHNPFQAPVQIELSLPPPSPATYRSKLPRGTLPELWFEYALLRRFGFVLDQEASARYPKDVEITYSSRPNTFEFSQFVHRSGVAFVQVLGGLDGFLWLNNRLYNSHTHALSQRHQHRDPRHAQQQQQQQQQGVVEAAEADKLRLELTRFCSDRDELERFYRRVLAQLLQVEKEESERDELAKEYARGIFQQAAGEDELSRRQAKSRQGSNSSSGTSADRPGALYALSQLSTGSERKSDA
What are the official names of this protein?
Vacuolar membrane-associated protein IML1.
What is the protein family that this protein belongs to?
Belongs to the IML1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: XYLK_DROME
Sequence: MNKRSVIIAGIVASLLGLALGANFYFMYYLSAEEGHLASVRALENMIRHKMRHLKPNYLNRNPRFFMFRNKLLKNYKAAPYENASVLWDIANWWPHENEVYPLYDSSMGQLLETLRREPITRVSNLGRGTQLKLLVRLSHQQKVIFKPQWYPREEVIDGMIYSGKDRHTAEVYAFYLGAVLDFRWTPIVVGRVVNLKKEIYAKGDPELQQTINIETDEDGREKYCLFGKCHYCNEEETVCGDERHNIEGVLIYIVPGTLAKRRSPWQRTYKDDKRAPWEDDMTYCKSLKNKMETIRLLDLIDASIFDYLIQNGDRHHYETREERVVLIDNGKAFGNPNKDHLDILAPLYQCCLLRKSTWDRLQVFSGGVLTEIIDRLSKQDALYPLITDKHKKGVERRLLVVYAVVEHCMDIEGDKMFKTL
What is the function of this protein?
Kylose kinase that mediates the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans.
What are the official names of this protein?
Glycosaminoglycan xylosylkinase homolog, Xylose kinase homolog.
What is the protein family that this protein belongs to?
Belongs to the FAM20 family.
What are the subcellular locations of this protein?
Golgi apparatus. Endoplasmic reticulum.
Protein: ARSC2_BACC1
Sequence: MENKKTIYFLCTGNSCRSQMAEAWGKQYLGDKWNVYSAGIEAHGVNPNAIKAMNEVNIDITNQTSDIIDANILNRADLVVTLCSHADSVCPSTPPHINRVHWGFDDPAGKEWSEFQRVRDEIGERIKRFSETGE
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase 2.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_BART1
Sequence: MQISIFAVGRMKSGAEQKLVQHYLDRFSKSSGAVGFHLKKLQEIPESRAQTACQRMEEEGRKLIEFLPEKCQLIVLDERGESISSAAFAEKLGCYRDEGIRDVIIALGGPDGHNEQIRNRADFLLSFGFMTWPHQIARILLTEQLYRAVTIANHHPYHRF
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_PSE14
Sequence: MTSDDRIKLEPIWKEALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLNNVKVVILGQDPYHGPNQAHGLCFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWADQGVLLLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEHQPHLVFLLWGAHAQSKQKLVDATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGIEPIDWRLPVL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_MANSM
Sequence: MRYFMSYSAPNIGFVSLGCPKNLVDSERILTELRTDGYNIIPTYENADLVIVNTCGFIDSAVQESLEAIGEALEENGKVIVTGCLGAKENQIREVHPKVLEITGPHSYEAVMEHVHKYVPRPERNPYTSLVPAQGVKLTPKHYAYLKISEGCDHKCTFCIIPSLRGDLDSRPITQVLDEAKRLVDSGVKELLVVSQDTSAYALDQSKENQNKTVFWNGAPIKNNLITLCRQLGTLGAWIRLHYVYPYPHVDDLIPLMAEGKILPYLDIPLQHASPKVLKAMKRPGSVERVLERIQKWREICPELTLRSTFIVGFPGETEEDFQMLLDFLQEAQLDRVGCFKFSPVEGAVATDMADQVPEEVKEQRFQRFMELQQQISAQRLQQKIGKTLPVIIDDIDEDGIIGRSMADAPEIDGVVYVDNRSESAVKIGDIIQVAITNADEYDLWGTC
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_CITK8
Sequence: MYQDKILVRQLGLQPYEPVSQAMHEFTDTRDENTPDEIWLVEHFPVFTQGQAGKAEHVLMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELVTLLEQTVVNTLAERGIDAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDLSPFLRINPCGYAGMEMAKISQWDNNATTDNIAPRLLANILALLNNPPHEYIPA
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_CLONN
Sequence: MDINYKLYLITDRSFLNGRSLAECVEDAIKGGATLVQVREKNISTRDFYNIAREVQEVTTKYNVPLLINDRIDIALAINADGVHLGQSDMPIELARKILGDDKVIGISAGNVKEAIEAEKAGADYVGLGTVFFTGTKKDIDEPIGLAGLKEITEKITIPSVAIGGINKENAKSVLATGVDGISVISAILKNDDIQGASKTLANI
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: LEUC_SHIBS
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: Y05C_BPT4
Sequence: MKQLIIKRLNLLICCLCIVIAYGYYAINDYMHYKDYDVTVVNTLTGTQGKGSSLSFIAVYELKDGYRFSEYISPETYSSIEKGDNITVSLRPFDVKQTWFDNIVWFFGMALVQSICGTYIVCSILFRVIGKIE
What are the official names of this protein?
Uncharacterized 15.3 kDa protein in nrdC-mobD intergenic region.
Protein: PUR4_RALSO
Sequence: MAHFSCFPGALALSAFRQQRLLSTLKRIDPEIDAVSAQYLHFVAADAPLSADDAARVQALLTYGSPASAETEGDRFVVIPRFGTISPWASKATEIARHCALPQIHRIERGVEFTVTCKKGLLRGLTGGRKQLDEATRAAVAAHLHDRMTEIVVATREAGYGLFDVLPAKALRFVDLGSGDAAAGRGALEAANTEMGLALSDDEIDYLVDAYRKLGRNPTDVELMMFAQANSEHCRHKIFNADWTIDGETQDKSLFAMIRNTHQLAPQGTVVAYSDNAAVMEGGMAERWFPHAGTDGETGVPQYGRREALTHTLMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGAKPKAGLTGFTVSNLLLPEAVQSWENARDTAQPAAQRNPGDTAPGPVGKPDRIASPLQIMIEGPIGGAAFNNEFGRPNLGGYFRVYEQNVGGTVRGYHKPIMIAGGIGNIDAGHTHKHGLPAGTLLVQLGGPGMRIGMGGGAASSMATGTNTADLDFDSVQRGNPEMQRRAQEVINACWALGEDNPILSIHDVGAGGISNAFPELVDGADRGARFDLRQVHLEESGLSPAEIWCNESQERYTLAIAPGDFPRFQAMCERERAPFSVVGFATEEQQLQVVDGDAPADAVEHFPVNMPMDVLLGKPPRMHRDVRRVAQALPEVDVTGLDLETVARDVLRHPTVASKSFLITIGDRTVGGLNTRDQMVGPWQVPVADVAVTTLDYKGYAGEAMTMGERTPLAVIDAPASGRMAIGEAITNIAAAPIASLAQLKLSANWMAACGVDGEDARLYDTVKAVGMELCPALGISIPVGKDSLSMRTKWDDAGEAKEVVAPVSLIVSAFAPVTDVRKTLTPQLKPVASAGEAADTTLIVIDLGHGKHRLGGSILAQVTQQIGNSVPDVGDAEDLKRFFAAIQQLNAAGMLLAYHDRSDGGLWATVCEMAFAGHCGVSINVDMLTLDGAHASDYGDAKNWAQQVSGRRADMTLRALFAEELGAVIQVPAAQRDAVFAVLREHGLAACSHVIGAPNASGQIEIWRDAKKVFSAPRIELQRAWTDVSWRIASLRDNPECTQSEYDRLLDAEDPGISPNLTFDLAEDVAAPFIATGARPRMAILREQGVNSQVEMAYAMDKAGFDAYDVHMSDLLAGRTRLADFKGFVACGGFSYGDVLGAGEGWAKTILFNGMLAEQFAAFFNRADSIALGVCNGCQMMANLAPIIPGAGAWPKFTRNQSEQYEGRLVTVQVEASPSIFYAGMEGSRIPIVVAHGEGYADFSQQGDIGKVAVGLRYVDNRGEVTQTYPLNPNGSPQGIASVTTHDGRFTVLMPHPERVFRAVQMSWHPKDWAAAGDGSSPWMRMFRNARKQMG
What is the function of this protein?
Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase, FGAM synthase, FGAMS, Formylglycinamide ribonucleotide amidotransferase, FGAR amidotransferase, FGAR-AT.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_SHEB2
Sequence: MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEVQKFTDAHIKKIDEILAAKEIELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGZ_ACTP2
Sequence: MLLIDIKDKELSQEEVEILEHPLVSGLILFSRNFHDKVQLEALVKSIRQRVKKPLLITVDQEGGRVQRFREGFTKLPAMQAFHTLAKNPQESTALARQTGWLMAAEMFALDIDLSFAPVLDLGHQCKAIGDRSFGENPDAMLPIAEAFIDGMREMGMATTGKHFPGHGHVLADSHLETPFDDRPKEAIFNRDILPFKQLISKGKLSAIMPAHVIYTQCDSQPASGSEYWLKQVLRNQLNFNGVIFSDDLGMKGAGFMGNFVERSEKAIHAGCDLLLLCNEPEGVIQVLDGLKYQPTKTQTERHISLMKRKTVRWNELEASPRYQQAQQRLTALQNDWLEYKAQHC
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUB_PARMW
Sequence: MDGPFGFVVIDKPAGHTSHSCVSRLRRCYGLKRVGHGGTLDPAVTGVLPIALGPATRLLPYLPGDKTYRGVIQLGSITSSDDLEGELLRQAPWPDLQPEELEVALAPFRGPIQQRPPQVSAVHVDGERAHARARRGEQMVLPPRPVTIHRLQLLHWDPNQGQLTLEVHCSAGTYIRSLARDLGEQLGCGGCLAQLRRTQALGFLESQAQALPEADATPPPPLSPLLALEHLPRRQLTDSEEADWRCGRRLSLDPGPGDAVVVCNADGSMAGIGLRQEDDQLQPKVVFDASG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: NADK_CAMJ8
Sequence: MQNKIDYKNIKKIGLVTRPNVSLDKEILKLQSILSIYKVELVLFKESSEILDLPKYGLDDLFKISDFVISLGGDGTLISLCRKACEYDKAVLGIHAGHLGFLTDFKVDEAENFFQAFFQGEFRIEKPYLLSVFLEDKQGKILEKLAFNDVVISKNNQASMAHIEVFRKEKKFNEYFGDGLIVATPAGSTAYNLSANGPIVYTLAQAFILTPVCSHSLTQRPIVLPKGFEIEIMAKDCILCIDGQENYKMNDFKSIKVGLSDKNVALIHPKNRDYFQILKEKLHWGN
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_BACHK
Sequence: MEIVCEDFQKVLTKIKLLRENANIIEETVQRSVREIVQNVRESRDEALFFYTKKFDGVEIKDVRVSEEEIKQASMFVESSFLEALQEAKKNIISYHEKQKRQSMFDCTSKGIIRGQIIRPLENIGVYVPGGTASYPSSVLMNVLPAKLAGVKKIVMVTPPRAGGIDPHILVAASLAGVDEIYMIGGAQAIAALAYGTESIPKVDKIVGPGNLYVALAKREVYGIVNIDMIAGPSEIVVIADETGNAKYIAADLLSQAEHDERATAICITTNIELAKEVEKEIERQLETLPRSEIARESINRNGAIFIVPSIDEALQLSNEIAPEHLELHIKEPMNALAYVKHAGSIFLGPYAPEPLGDYLAGPNHVLPTSGTARFFSPLSVDDFVKKSSFLSYTEEALRDVKHHIVELANKEGLHAHAKAIQIRFGEEE
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: TAL_THEAC
Sequence: MKIFLDTANIDEIRTGVNWGIVDGVTTNPTLISKEAVNGKKYGDIIREILKIVDGPVSVEVVSTKYEGMVEEARKIHGLGDNAVVKIPMTEDGLRAIKTLSSEHINTNCTLVFNPIQALLAAKAGATYVSPFVGRLDDIGEDGMQIIDMIRTIFNNYIIKTQILVASIRNPIHVLRSAVIGADVVTVPFNVLKSLMKHPKTDEGLAKFLEDWKKVSPDGKLIL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G23A_DROME
Sequence: MFPPTRVQASSRVVLKIFHFILVAFSLRSRRLSRLVLWLQFLGWLTWFISMWTQSVIYAQTIDCTLDCSLRHILTFFQTVSHAFIVVTSFLDGFRIKQDQLDEPIAFEDSDPWLAFTVLAMLVPTLGVEYLVCSNAPEYAFRIRIYHLKTLPSFLALQVQIISFILEVMKVNIRVRQTKLQLLILARELSCRWPQRKQKPQFSDQQAHRVKDLKRRYNDLHYLFVRINGYFGGSLLTIIIVHFAIFVSNSYWLFVDIRTRPWRIYAILLNLGFIFNVALQMAAACWHCQQSYNLGRQIGCLISKLVKPQGSKLYNDLVSEFSLQTLHQRFVVTAKDFFSLNLHLLSSMFAAVVTYLVILIQFMFAERSSTRGSG
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Gustatory receptor 23a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATA_ALIFM
Sequence: MGGISIWQLLIIAVIIVLLFGTKKLRGVGSDLGSAVKGFKKAISEDEPAKDAKKDADFVPQNLEKKEAETVEKQKQNDKEQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: OSTD_YEAST
Sequence: MQFFKTLAALVSCISFVLAYVAQDVHVSFPSTAGKSRVMIGKVEPRIGIDETVPTTITVEDPNEVIQVNFAIESTNKPFQNTLLIGLPNKNLEMAFEPEIKDNGKLSMYKYRIDLAKLDAALLQEASRSPEPIKATLILASSTAKPKENLFREILQLNLNFDVDHSDSSLVDKFGIKPEIHHIFHAEPKRVAKPIAVIFVLIIFITILSLIVTWLNSCAAAFNNIPTGVTAVYFLGFIATIVGFEVIFARYYLGTSIFETLFSSLYLGAPGLLTSTKFLRSFGQTI
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1, Oligosaccharyl transferase subunit SWP1, Oligosaccharyl transferase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the SWP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GATY_ECOLC
Sequence: MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADALYTNPAQAREFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
What is the function of this protein?
Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP).  Requires GatZ subunit for full activity and stability.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatY, TBPA, TagBP aldolase, D-tagatose-bisphosphate aldolase class II, Tagatose-bisphosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase GatY subfamily.
Protein: RIC8_CAEEL
Sequence: MSEELHSDLIASIFGGKPAKIEEFFSKWNFANAAVSKFDMANSAKNELGDRICEVIENGELTHVLLETIKILSREKDGLEGLLNDPLCDKILAFAELSSNENNSKTVHTLMEAQKCLINTLFHSQRMRDRFYANPKTGENLQFFLGEFEENRRKTSSIDWIRLLNPVQAAEIWYFYHRIAFIATALGREFQKNWANDPKTIDSLLLAVEICTNRSENSTQDINRATEALKTFFNVFCHFHGDVKAIDHKNAAKTCQILRDAICSDVLTDDVVQSAIHCLSVPPLPMVLSVLCGKNSKNNGGENEEEKFFVEELSNMQLTEAILMHLDKQLTKVVALLLNDAPNQQQNPMLSAEASTLTDLVGPYFQVLARLCTDSKYVRRYCRIRVIPPLVSEEVQKRPEENNTLRGRIARIMMLPSSTKDVAAEFLFIICKRSVNRMIKYLGFGHSAGHLANLGLLGQINQPKHASDSEDSETEDYNQIKDSVNPVTGAIYPSDHGSALAGMSEEQKEYEAMKLVDAMNQMMETGIVKPGTIGDDGKIREVSHVLELLKNAPEPAPAENSDSDEE
What is the function of this protein?
Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins independently of G-protein coupled receptors.  Acts by exchanging bound GDP for free GTP.  Able to facilitate synaptic transmission in the nervous system probably by activating G(q)-alpha (egl-30).  Also able to activate the G(s)-alpha in synaptic signaling network.  Plays a key role in asymmetric spindle positioning, a step for asymmetric cell division that generates cell diversity during development by activating G(i)-alpha protein goa-1 and gpa-16 independently of G-protein coupled receptors.  While it acts as a GEF for goa-1, it has no GEF activity toward gpa-16.  In addition to its GEF activity, it is required for cortical subcellular localization of G-alpha proteins such as gpa-16.  Also required for the interaction of goa-1 and gpr-1/2, suggesting that it may act by generating G-alpha proteins free from G-beta-gamma subunits, enabling gpr-1/2 to mediate asymmetric cell division.
What are the official names of this protein?
Synembryn, Resistance to inhibitors of cholinesterase protein 8.
What is the protein family that this protein belongs to?
Belongs to the synembryn family.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Note=Localizes to the cell cortex. Excluded from interphase nuclei and becomes localized around what appeared to be kinetochore microtubules at the onset of mitosis, becoming more diffuse during anaphase.
Protein: PUS10_HALLT
Sequence: MDVLEVAARATGTGPVCDACLGRLVADRSFGLSNAERGSALRTSLALRDDEDYEPVETADCWVCEGRCTEFDEWAERAAEAVEDVEFATYNVGTRPPPLIEENEALLREEAGLDDDAGEPFKSEFNREVGKRFGRLTETEVSFDRPDVQFTIDLAEDEIDAKVNSTFVYGRYRKLERDIPQTEWPCRECKGSGRQGADPCDHCGGSGYLYDDSVEEYTAPVVEDVMDGTEATFHGAGREDVDALMLGTGRPFVIEVEEPRRRRVDTDRLQADINAFADGAVEVEGLRLATYDMVERVKEHDAAKRYRAEVAFDADVDADALAAAVEELEGTTVEQYTPNRVDHRRASITRERDVYEATAELDDARHAIVEIHGEGGLYIKELISGDEGRTEPSLAGLLGVGAEVTALDVVAVEGEDEPFEREEFFRE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase Pus10, tRNA pseudouridine 54/55 synthase, Psi54/55 synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase Pus10 family.