PharMolix/UniProtQA huggingface dataset:
Protein: EFG_RICFE
Sequence: MSKINKLEHIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCRWQDKIINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYRCVEMIKDRLGAKPLVIQLPVGIEESFKGIIDLVKMKAVIWKDESLGAEYFEEDIPADMKDKAEEYRAKLLDMVVELDDAIMEKYLSGEEVTEEEIKRLIRRGTISAAFYPVLCGSAFKNKGVQPLLDAVVDFLPSPIDIGIVKGMEVSTGEEKDFPISITEPFSALAFKIMNDPFVGSLTFIRIYSGKITSGSTVINTVKNKREKIGRMLLMHANNREDVKEASAGDIVALAGLKDTTTGDTLSDMDKQVILERMEFPEPVIELAVEPKSTADQEKMGLALSRLAAEDPSFRVSTDHETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRETITKACEIDYTHKKQSGGAGQFARVKIIFEPLKEVKDLKDEDKNKTFVFESKIVGGAVPKEYIPGVEKGLNNIRETGVIAGYPMIDFKATLVDGAFHDVDSSVLAFEIAAKAAFREGMPKGNPKLLEPIMKVEVITPDEYMGDIIGDLNSRRGQIQSMDPRGNAQVVTANVPLAEMFGYVNTLRSLSQGRAQFSMIFSHYDQVPSQVADIIKAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS3_LISMH
Sequence: MISVDFSKGLVPTIILDDQNGDVLMLAYMNEESYHKTLETGYTWFFSRSRNELWNKGATSGHTQKVKQIWTDCDNDTLLIRVTQIGPACHTGKKSCFFNLIKEDF
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNT_ECOHS
Sequence: MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALGQTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAEEV
What is the function of this protein?
Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang.  Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A).  Also appears to be involved in tRNA biosynthesis.
What are the official names of this protein?
Ribonuclease T, Exoribonuclease T, RNase T.
What is the protein family that this protein belongs to?
Belongs to the RNase T family.
Protein: GCSP_BURP6
Sequence: MKLEHPDRLMNRTPLSLAALETHDAFAERHIGPDAASQQAMLDTLGFATRAALIDAVIPASIRRAETLPLGPFAQPKSEAEALAALRALADKNQVFRSYIGQGYYNTHTPAVILRNVLENPAWYTAYTPYQPEISQGRLEALLNFQQMVADLTGLEISNASLLDEATAAAEAMTLLQRVGKPQSNVFYVADDVLPQTLEVIKTRAKPIGIEVKSGPAADAAAANAFGVLLQYPGANGDVRDYRALADAIHAAGGHVVVAADILALTVLMPPGEWGADVAVGNTQRFGVPMGFGGPHAAYMAVRDEFKRQMPGRLVGVTVDAQGKPALRLALQTREQHIRREKATSNVCTAQALLAIMASMYAVYHGPRGLKTIALRVNRIAALLAAGIRHLGYATVNDTFFDTLTIDTGARTAQLHAFAQAKRINLRRAGDTRVGVSVDETTTRADLADLLTIFAQAAGATAPDIDALDAGLLPAPALPPSLERTSAYLTHHVFNRHHSETEMLRYLRSLSDKDLALDRSMIPLGSCTMKLNATSEMLPVTWPEFGRIHPFAPAEQTVGYREMIDQLEQMLVAATGYAAVSLQPNAGSQGEYAGLLIIHAYHESRGESHRDVCLIPASAHGTNPASAHMAGMKVVVVACDAQGNVDIADLKAKADAHSHDLAAIMITYPSTHGVFEQNVREICEIVHAHGGQVYVDGANMNAMVGLTAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGPHLAKFLPNQRSTGYARGEDGIGAVSAAPYGSASILPISWMYIAMMGAKNLTAATETAILNANYIAKRLAPHYPVLYSGPGGLVAHECILDLRPIKDSSGITVDDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESQEELDRFIAAMIAIRDEIRAVEEGRADREDNPLRHAPHTAAVVTANEWPHAYSREQAAFPVASLVANKYWPPVGRADNAYGDRNLFCSCVPVSDYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: EI3F1_DROGR
Sequence: MSALNLTVRVHPVVLFQVVDAFERRNADSHRVIGTLLGSVDKGVVEVTNCFCVPHKEHDDQVEAELSYALDMYDLNRKVNSNESVVGWWATGNEVTNHSSVIHEYYARECNNPVHLTVDTSLQGGRMGLRAYVCIQLGVPGGKTGCMFTPIPVELTSYEPETFGLKLLQKTVGVSPAQRPKTVPPMLDLAQISEASQKLQSLLDLILKYVDDVIAHKVTPDNAVGRQLLDLIHSVPHMTHEQFTQMFNANVRDLLMVITLSQLIKTQLQLNEKLTFLPTA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F-1, eIF3f-1, Eukaryotic translation initiation factor 3 subunit 5-1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIBIN_RAT
Sequence: MMFTKLIWMGFFCHLCRGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDRRRCSQGEGGQASSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLGISVGLRDKYELLAHTIRSHGTRLGRLKSDYLEGGGQKMG
What are the official names of this protein?
Fin bud initiation factor homolog.
What is the protein family that this protein belongs to?
Belongs to the FIBIN family.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Endoplasmic reticulum.
Protein: DNLJ_ENT38
Sequence: MDSIEQQLTQLRTTLRHHEYLYHVMDAPEVPDAEYDRLMRELRELEAQHPELVTPDSPTQRVGAAPLASFSQVRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSADTLTWCCELKLDGLAVSILYENGLLVRAATRGDGTTGEDITANVRTIRAIPLTLRGDNIPARLEVRGEVFLPQKGFEKINDEARRTGGKIFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGVLPDTHLGRLLQFKEWGLPVSNRVQLCDSPEAVLAFYHKVEEDRPSLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIARLGLRIGDKVVIRRAGDVIPQVVNVVESERPDDTREIVFPAHCPVCGSDVERVEGEVVTRCTGGLICGAQRKEALKHFVSRRALDVDGMGDKIIDQLVEKEYVHTPADLFRLSAGKLTGLDRMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAHFGTLEQLEKATIDDLQKVPDVGIVVATHVFNFFAEESNRDVIGKLLEEGIHWPAPVVINVEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVAIGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIDVIDEAEMLRLFGE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RUVC_POLNA
Sequence: MHILGIDPGLQITGFGVVDMDGPHLRYVASGTIKTTHLDTKDLPGRLKVLFDGVREVVQRYQPEVASVEIVFVNVNPQATLLLGQARGACITALVSSDLAVAEYTALQMKKAVAGYGKAGKAEVQQMVMRLLKLPSLPGKDAADALGLAITHAHVGTAMARLALASEAGGKMDGNYRAGRSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RL17_BORPD
Sequence: MRHGNGLRKLNRTSSHRLAMFRNMAVSLITHEAIKTTLPKAKELRRVVEPLITLGKEPTLANKRLAFARLRDRAAVVKLFAEIGPRYAARNGGYTRVLKMGFRQGDNAPMAYMELVDRPEVEETEADNAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HIS2_STAAM
Sequence: MTKYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGVVCFYSRSKQRLWTKGETSGHTQLVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTEVPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKAFVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPIA1_HUMAN
Sequence: MFCCLGYEWLSGGCKTWHSAWVINTLADHRHRGTDFGGSPWLLIITVFLRSYKFAISLCTSYLCVSFLKTIFPSQNGHDGSTDVQQRARRSNRRRQEGIKIVLEDIFTLWRQVETKVRAKIRKMKVTTKVNRHDKINGKRKTAKEHLRKLSMKEREHGEKERQVSEAEENGKLDMKEIHTYMEMFQRAQALRRRAEDYYRCKITPSARKPLCNRVRMAAVEHRHSSGLPYWPYLTAETLKNRMGHQPPPPTQQHSIIDNSLSLKTPSECLLTPLPPSALPSADDNLKTPAECLLYPLPPSADDNLKTPPECLLTPLPPSAPPSVDDNLKTPPECVCSLPFHPQRMIISRN
What are the official names of this protein?
Nuclear pore complex-interacting protein family member A1, Nuclear pore complex-interacting protein, NPIP.
What is the protein family that this protein belongs to?
Belongs to the NPIP family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane. Note=Colocalizes with nuclear pore complex protein NUP62.
Protein: RODZ_SALAR
Sequence: MNTEATHDQNEAQTTGVRLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPSDLASTFLRGYIRSYARLVHVPEEELLPGLEKQAPLRAAKVAPMQNFSLGKRRKKRDGWLMSFTWLVLFVVVGLTGAWWWQNHKAQQEEITTMADQSTAELNADKDSGQGVQLDTRAAASQDTTPAETAPAAPVDSTAAATQNTVVAPSQANVDTAATSATATETSSALPTDQAGVAAPAADSNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTINAEPTSAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: NCOA1_MOUSE
Sequence: MSGLGDSSSDPANPDSHKRKGSPCDTLASSTEKRRREQENKYLEELAELLSANISDIDSLSVKPDKCKILKKTVDQIQLMKRMEQEKSTTDDDVQKSDISSSSQGVIEKESLGPLLLEALDGFFFVVNCEGRIVFVSENVTSYLGYNQEELMNTSVYSILHVGDHAEFVKNLLPKSLVNGVPWPQEATRRNSHTFNCRMLIHPPEDPGTENQEACQRYEVMQCFTVSQPKSIQEDGEDFQSCLICIARRLPRPPAITGVESFMTKQDTTGKIISIDTSSLRAAGRTGWEDLVRKCIYAFFQPQGREPSYARQLFQEVMTRGTASSPSYRFILNDGTMLSAHTKCKLCYPQSPDMQPFIMGIHIIDREHSGLSPQDDSNSGMSIPRINPSVNPGISPAHGVTRSSTLPPSNNNMVSARVNRQQSSDLNSSSSHTNSSNNQGNFGCSPGNQIVANVALNQGQAGSQSSNPSLNLNNSPMEGTGIALSQFMSPRRQANSGLATRARMSNNSFPPNIPTLSSPVGITSGACNNNNRSYSNIPVTSLQGMNEGPNNSVGFSAGSPVLRQMSSQNSPSRLSMQPAKAESKDSKEIASILNEMIQSDNSDNSANEGKPLDSGLLHNNDRLSEGDSKYSQTSHKLVQLLTTTAEQQLRHADIDTSCKDVLSCTGTSSSASSNPSGGTCPSSHSSLTERHKILHRLLQEGSPSDITTLSVEPEKKDSVPASTAVSVSGQSQGSASIKLELDAAKKKESKDHQLLRYLLDKDEKDLRSTPNLCLDDVKVKVEKKEQMDPCNTNPTPMTKPAPEEVKLESQSQFTADLDQFDQLLPTLEKAAQLPSLCETDRMDGAVTGVSIKAEVLPASLQPTTARAAPRLSRLPELELEAIDNQFGQPGAGDQIPWANNTLTTINQNKPEDQCISSQLDELLCPPTTVEGRNDEKALLEQLVSFLSGKDETELAELDRALGIDKLVQGGGLDVLSERFPPQQATPPLMMEDRPTLYSQPYSSPSPTAGLSGPFQGMVRQKPSLGAMPVQVTPPRGTFSPNMGMQPRQTLNRPPAAPNQLRLQLQQRLQGQQQLMHQNRQAILNQFAANAPVGMNMRSGMQQQITPQPPLNAQMLAQRQRELYSQQHRQRQIIQQQRAMLMRHQSFGNNIPPSSGLPVQMGTPRLPQGAPQQFPYPPNYGTNPGTPPASTSPFSQLAANPEASLATRSSMVNRGMAGNMGGQFGAGISPQMQQNVFQYPGPGLVPQGEATFAPSLSPGSSMVPMPVPPPQSSLLQQTPPTSGYQSPDMKAWQQGTMGNNNVFSQAVQSQPAPAQPGVYNNMSITVSMAGGNANIQNMNPMMGQMQMSSLQMPGMNTVCSEQMNDPALRHTGLYCNQLSSTDLLKTDADGNQQVQQVQVFADVQCTVNLVGGDPYLNQPGPLGTQKPTSGPQTPQAQQKSLLQQLLTE
What is the function of this protein?
Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion.  Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs).  Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors.  Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear.  Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors.  Required with NCOA2 to control energy balance between white and brown adipose tissues.  Required for mediating steroid hormone response.  Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.
What are the official names of this protein?
Nuclear receptor coactivator 1, NCoA-1, Nuclear receptor coactivator protein 1, mNRC-1, Steroid receptor coactivator 1, SRC-1.
What is the protein family that this protein belongs to?
Belongs to the SRC/p160 nuclear receptor coactivator family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAB_SULSY
Sequence: MKFYIKTFGCQMNVNDSEKMAGILQTLGYTPTENWEEADVILVNTCSVREKPDQKVLSALGEFKKVKKHNPNAVIGVCGCLAQRAGYEIYQKAPFIDIVFGTTNIHHLPNLLEEAKSGNKAIEILEEIDENENLLDQFPTVRENKYTAFVTVIRGCDKKCTYCIVPTTRGRERSRRIGDILREVQYLVEDGVKEIHLIGQNVTAYGKDFGDVKFWELLKAVAEVDGVERIRFTTGHPRDLDEDTIKVMADLPQICEALHLPIQAGSDRILQAMDRGYTQKEYLQKIELLKKYIPNIALSTDIIVGFPGETYEDYLETVKVIKEVEYDQVFAFKYSPRPGTPAADLPMTESPEELSKRLNDLINLQKDITFKKNLEYQDKIVEILVEEINQENKLVGRTRTNKLVYAEGSPEYLGKLVNVKIEKVNRFSLEGSIIGGD
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ONYPE
Sequence: MSRVGNKAIEVPNAVKVDIKDRNFISVEGPKGKLEYQFNHRLTITNENKVITVKRPNDEIFMKKIHGTTRALLSNMVEGVSKGFQKTLKIVGLAYRAQIKDKQLILSLGFSHPVSVAIPDNLEVVVNQNTEIVIKGIDKQLVGEFAAKNVKLRKPEPYKGKGIRYVGQYVRQKAGKSAKKTRKD
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CCNE1_DANRE
Sequence: MPSKKVLQTEHINTTDEAPKTTSVRPRKRKADVAIHLQDPDEEVTEMTRKKQCASQACWNPDTGYTSPCRRIPTPDEVEEPVAFGSVGFTQYASESIFITPTRSTPLPALCWASKDEVWNNLLGKDKLYLRDTRVMERHPNLQPKMRAILLDWLMEVCEVYKLHRETFYLGQDYFDRFMATQENVLKTTLQLIGISCLFIAAKMEEIYPPKVHQFAYVTDGACTEDDILSMEIIIMKELNWSLSPLTPVAWLNIYMQMAYLKETAEVLTAQYPQATFVQIAELLDLCILDVRSLEFSYSLLAASALFHFSSLELVIKVSGLKWCDLEECVRWMVPFAMSIREAGSSALKTFKGIAADDMHNIQTHVPYLEWLGKVHSYQLVDIESSQRSPVPTGVLTPPPSSEKPESTIS
What is the function of this protein?
Essential for the control of the cell cycle at the G1/S (start) transition.
What are the official names of this protein?
G1/S-specific cyclin-E1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin E subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPSB_LEVBA
Sequence: MENVNFTPKEILQKQFRQKMRGYDPDDVDSFLDNVIKDYDAFVKENQRLQDENERLLAKVDELTRQVQVGASQPRAAATSPASSNVTNMDILKRLSNLERHVFGSQLDNDPNESHRL
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: YEAL_ECO81
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFPWIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSH3A_MOUSE
Sequence: MAATNIWAALPAKKRPLHQRARRPAGGRGREPEVPFTTDPSGNPAGRNCLEFLPPGGTSGCSATDGGATVPLALRPFLRERRPLGSQHPCPWHYLQVSDYDDSLAPTCFRAHLHRRGSSSTLNQASAMTDPNPRTAEASGLYTYSSRPRAVACQRRRHRDSILQPVEEPMSYGNIMYDRRVIRGNTYALPTGQVPGQPDPLELQRQQQARRRALARKRAQEQLKPRTPEPVEGRKHVDIQTELYLEEIADRIVEVDMECQTDAFLDRPPTPLFIPAKTGKDVATQILGGELFDFDLEVKPMLEVLVGKTIEQSLLEVMEEEELANLRARQYAYEEIRNVELAEVQRLEEQERRHREEKERRKKQQWEIVHKRNETLQKISALIFARQYLANLLPSVFDKLRNSGFFYDPIERDIEVGFLPWLMNEVEKSMEHSMVGRTVLDMLIRDVVERRINDYEHKEAMPPGQKTNVINGPNTVTDPSVTTLHTQKPVLDRVSSQPAPSQERKPVEEGGHLMAE
What is the function of this protein?
May function as part of axonemal radial spoke complexes that play an important part in the motility of sperm and cilia (By similarity).  Functions as a protein kinase A-anchoring protein that scaffolds the cAMP-dependent protein kinase holoenzyme.  May serve as a point of convergence for MAPK and PKA signaling in cilia (By similarity).
What are the official names of this protein?
Radial spoke head protein 3 homolog A, A-kinase anchor protein RSPH3A, Radial spoke head-like protein 2A.
What is the protein family that this protein belongs to?
Belongs to the flagellar radial spoke RSP3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: TPIS_XYLFA
Sequence: MRPKIVAGNWKLHGSHAFAQALVAQVAAGLPLLGVSVIILPPLLYLSDLAQRFKGEGLAFGAQNVSHHDKGAYTGEVSAAMVADVGAHYTLVGHSERREYHHEDSELVARKFAAALSAGLRPILCVGESLPQREAGQAEVAIAMQLAPVLALVGPQGVARGLIAYEPVWAIGTGRHADPSQVQAMHAFIRGEIARQDARIGDSLLILYGGGIKPCNAAELFSQQDVDGGLIGGASLVADDFLAIARATV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_MYCGA
Sequence: MNRFIKSATSLKDCINDSKKEVCLIGRSNVGKSTIINGLANAKIAQTSKTPGRTVTMNFYEISNQRIVDLPGYGYARIKKSQKEEISLFLSDYLNHRKNLVGIFLILDLGVITDQDIEIVRLLTTLDVEYYIVFNKIDKYPKSAYINNKEKILDALKVNEDRILLISAKNKQNLNNLMLKIIDVIS
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: Y029_SIFVH
Sequence: MQLKATSFRANEKIIFVLNSNKLFCETYDEFLNRLIDECEGAINYANNDITETLSIYSFKLSSETIGKLSTIAKKYRISRSEAFRKLIIAKAEGLC
What are the official names of this protein?
Uncharacterized protein 29.
Protein: GATZ_ECO27
Sequence: MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFAIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKAYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCHAAESVATDCQREQLNYVIGTEVPVPGGEASAIQSVHITQVEDAANTLRTHQKAFIARGLAEALTRVIAIVVQPGVEFDHSNIIHYQAQEAQALAQWIEKTKMVYEAHSTDYQTQTAYRELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSRCVAVIEEVMLDEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQSGELSAIPHQLIMDKIYDVLRAYRYGCAE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: HLDE_HELPS
Sequence: MKQILVVGDLIADYYLWGRSERLSPEAPVPVLEVQRESKNLGGAANVANNLISLKAKVFLCGVVGDDLEGEHFINALKARNIDTSCILTDKTRCTTLKTRIIAQNQQIVRVDKEIKDPLNADLRKKLLDFFTEKIQEIDGVILSDYNKGVLDFELTQKMIALANKHHKLILCDPKGKDYSKYAHASLITPNRIELEHALHLKLDSHANLSKALQILKETYHIAMPLVTLSEQGIAFLEKGELVNCPTIAKEVYDVTGAGDTVIASLTLSLLESMSLKEACEFANAAAAVVVGKMGSALASLEEIALILNQTHPKILPLEKLLETLEHHQQKIVFTNGCFDILHKGHASYLQKAKALGDILIVGLNSDASVKRLKGDKRPIVSEKDRAFLLASLSCVDYVVVFEEDTPIKLIQALKPDILVKGADYLNKEIIGSEFAKETRLMEFEEGYSTSAIIERIKRTCND
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RSMH_FRATN
Sequence: MHYSVLLQESINDLNINPQGIYIDATFGRGGHSKAILNRLTTGRLIAFDKDLDAISYARENFQFSNFEIVHASFASIYDYCLQHSLLGKIDGIIMDLGVSSPQLDNAARGFSFTHNGPLDMRMDVSKGITASQALEELSVDDLSYIFKVYGEERFARKIALRIKDYIQQNGSISTTLELAELIRATIGKKEKKNPATRCFQALRIYVNNELKDLEALLENILAVIKSGGRIAAISFHSLEDRIVKQKFSALINPKQELNRITKMLPQDSSQIKLKWITKKSKANEDELNQNVRSRSAILRVVEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_BORA1
Sequence: MSSRSYKRVLLKLSGEALMGDDAFGINRSTIVRMTDEIAEVAAMGVELAIVIGGGNIFRGVAPGAQGMDRATADYMGMMATIMNALALQDALKHKGLDTRVQSALNIDQVVEPYIRPKTLRYLEEGKVVIFAAGTGNPFFTTDTAAALRGAEIGAEIVLKATKVDGIYSADPNKDPTATRYARISFDEAIVRRLEVMDATAFALCRDQKLPIKVFSINKSGALKRVVGGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSN3_HUMAN
Sequence: MGQCGITSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTLIPAVVIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEGCEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPAYELLITGGTYA
What is the function of this protein?
Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.
What are the official names of this protein?
Tetraspanin-3, Tspan-3, Tetraspanin TM4-A, Transmembrane 4 superfamily member 8.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.