PharMolix/UniProtQA huggingface dataset:
Protein: RS26_DICDI
Sequence: MTQKRRNHGRSKHGRGSVPYIRCTNCARCVPKDKAVKRFYIRPIVENAAVKDISDQGVFNVKGYKFPRTYVKSQYCISCAIHSHIVRVRSVADRKIRTRPSRPGVKKPTAAK
What are the official names of this protein?
40S ribosomal protein S26.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS26 family.
Protein: KBTB4_MOUSE
Sequence: MKGGIADSWQREKLATMESPEEPGASMDENYFVNYTFKDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLLVDYIYHGTVKLRADELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSDPELYTAAKHCAKTHLAQLQSTEEFLHLPHHLLTDIISDGVPCSQNPTEAIEAWINFNKEEREAFAESLRTSLKEIGENVHIYLIGKESSRTHSLAVSLHCAEDDSISVSGQNSLCHQITAACKHGGDLYVVGGSIPRRMWKCNNATVDWEWCAPLPRDRLQHTLVSVPGKDAIYSLGGKTLQDTLSNAVIYYRVGDNVWTETTQLEVAVSGAAGANLNGIIYLLGGEENDLDFFTKPSRLIQCFDTETDKCHVKPYVLPFAGRMHAAVHKDLVFIVAEGDSLVCYNPLLDSFTRLCLPEAWSSAPSLWKIASCNGSIYVFRDRYKKGDANTYKLDPATSAVTVTRGIKVLLTNLQFVLA
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 4, BTB and kelch domain-containing protein 4.
Protein: Y600_TREPA
Sequence: MIKIIIGVVVLGIVVLFHELGHFVAALWCRVEVLSFSVGMGPVLFRKKFGKTEYRLSMLPLGGYCGMKGEQAFQTALDQKLSRIPVEPGSLYAVGPLKRMGIAFAGPLANVLMAVMVLALVSALGSRVHTFGNRISPVYVYDSSDNSPARRVGLQDGDTILRIGDQPIRYFSDIQKIVSQHAQRALPFVIERRGQLMHVTITPDRDAHTGMGRVGIYHYVPLVVAAVDAHGAASRAGLEPEDKILAVAGRRVQHAVQLLALLKEFRKKSVVLTVLRSGKRRYHTIALVRTENGAIDVGIEWKAHTVVIPGTSFFASVRAGIAETLRMCVLTVKGIGMLFRGLQFQQAISGPLRITHVIGDVAQHGFQESFLTGLSQLCEFVALVCVSLFIMNLLPIPILDGGLILFACVELFMQRSIHPRVLYYLQFVGFAFVALIFLCAFWNDVNFLFH
What are the official names of this protein?
Putative zinc metalloprotease TP_0600.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SNX16_PONAB
Sequence: MATPYVPVPMPIGNSASSFTTNRNQRSSSFGSVSTSSNSSKGQLEDSNMGNFKQTSVPDQMDNTSSVCSSPLIRTKFTGAASSIEYSTRPRETEEQNPETVNWEDRPSTPTILGYEVMEERAKFTVYKILVKKTPEESWVVFRRYTDFSRLNDKLKEMFPGFRLALPPKRWFKDNYNADFLEDRQLGLQAFLQNLVAHKDIANCLAVREFLCLDDPPGPFDSLEESRVFCETLEETNYRLQKELLEKQKEMESLKKQLSEKQLHIDTLENRIRTLSLEPEESLDVSETEGEQILKVESSALEVDQDVLDEESRADNEPCLHFSEPENAISEIEVAEVAYDAEED
What is the function of this protein?
May be involved in several stages of intracellular trafficking.  Plays a role in protein transport from early to late endosomes.  Plays a role in protein transport to the lysosome.  Promotes degradation of EGFR after EGF signaling (By similarity).
What are the official names of this protein?
Sorting nexin-16.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Lysosome.
Protein: RL15_PSET1
Sequence: MHLNTLSPAAGSKTAPKRVGRGIGSGLGKTGGRGHKGQKSRSGGKVRVGFEGGQMPMQRRLPKFGFTSRKSLVSAEINLYEIAKVEGDVVDLSALQAAGLVKKNVLFVKVVKSGEVSRAVTVKGLRATKGAREAIEAAGGKVED
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: SAHH_PETCR
Sequence: MALSVEKTAAGREYKVKDMSLADFGRLELELAEVEMPGLMSCRTEFGPSQPFKGARITGSLHMTIQTGVLIETLTALGAEVRWCSCNIFSTQDHAAAAIARDSCAVFAWKGETLQEYWWCTERALDWGPDGGPDLIVDDGGDATLLIHEGVKAEEEYKKSGAIPDPASTDNAEFQIVLSIIRDGLKSDPMKYHKMKDRLVGVSEETTTGVKRLYQMQQNGTLLFPAINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMIAGKVALIAGYGDVGKGCAAAMKQAGARVIVTEIDPICALQATMEGLQVLPLEDVVSEVDIFVTTTGNKDIIMVSDMRKMKNNAIVCNIGHFDNEIDMLGLETYPGVKRITIKPQTDRWVFPDTGRGIIILAEGRLMNLGCATGHPSFVMSCSFTNQVIAQLELWNEKSSGKYEKKVYVLPKHLDEKVAALHLGKLGAKLTKLSKDQADYISVPVEGPYKPAHYRY
What is the function of this protein?
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
Protein: MUTS_CLOB8
Sequence: MALTPMMVEYMKTKEEYSDCILFYRLGDFYEMFFDDAITVSRELELVLTGKNCGLEERAPMCGIPHHAAAAYIPRLVNKGYKVAICEQLEDPKEAKGIVKRGVVKIITPGTFIDANSSLENDNTYLMTIYESDERIGLAVSDISTGEFKTTSFDNIKITLLDEISKVAPKEILVDKNISQSLIDDIKGITTALITEKDFNEFIVSKEEIIDQFSDLEVSGLVNEREISSRVLLKYIYETQKMSLTNINLLEQYEIINYMTIDGNSRRNLELTESIREKSKKGSLLWVLDKSATSMGGRTIRKWIEEPLIIKSEIEKRLSGVSEAFSSISFNEDLRSSLKDIYDIERIVGKISNKNVNAKDMLSLKASLDKLPSIKELLGTANSELLKEYYENLDELSDIRELLESSIKEEPSLSIKEGNIIKDGYNSEVDELRQSKLHGKEWIAALENREREFTGIKSLKVGYNKVFGYYIEISKSNYNSIPEGRYVRKQTLANAERYITEELKIMEDKILGAEEKLINLEYSLFTDIRDSIEKEIARLKKSARIISNLDGISTLALIALENDYVKPEINEDGIIEIVDGRHPVVEKVIGRGEFVSNNTTLNQSDKELLLITGPNMAGKSTYMRQVALITLMAQIGSFVPASSANISICDKIFTRIGASDDLAGGKSTFMVEMWEVSNILKNATSKSLVLLDEVGRGTSTYDGLSIAWSVIEYITGNENLRCKTLFATHYHELVKLEGVLPGVKNYSVAVKKMKDSVIFLRKIVEGGADESYGIEVAKLAGLPDDVINRAKEILLGLEGENNFDIHKVTNTEIIENEVAVDINQANNVVTITEKACESKSEYIEKVEAKDSFDKAKSNKDDHRIDEKTENSSKKHKNKDSSNNMQLDFTFIEKEAFLKEVSEVDILSLNPMEAMNTLYRLVAEAKKLK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: YXIJ_BACSU
Sequence: MLQKLRKRQRELEEKQYPDELYGFEAEIYEFFMLVAGSLDYVLANKRIPRHQRRSLEKSFFELYPDILPDMIKNDKDLYHHILLYEQVRQEICVALSN
What are the official names of this protein?
Uncharacterized protein YxiJ.
Protein: CMOB_YERPY
Sequence: MIEFGDFYRLIAKGPLSPWLDTLPAQLSAWQRESLHGKFKTWFNAVEHLPQLTPTTLDLHSGVRAEMSPPISAGQREGMENMLRALMPWRKGPFSLYGLEIDTEWRSDWKWQRVLPHISPLAGRTILDVGCGSGYHLWRMIGEGAHLAVGIDPMQLFLCQFEAIRKLLGGDQRAHVLPLGIEQLPELAAFDTVFSMGVLYHRRSPLDHLYQLKNQLVTDGELVLETLVVEGDSQQVLVPGDRYAQMRNVYFIPSAPALKAWLEKCGFVDVRIADMAVTTTEEQRRTDWMTSESLAEFLDPHDHSKTVEGYPAPLRAVLIARKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RF3_SHEHH
Sequence: MSGNKVEVDKRRTFAIISHPDAGKTTITEKVLLFGNALQKAGTVKGKKSGQHAKSDWMEMEKDRGISITTSVMQFPYHDALVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEQRTIKLMEVTRLRDTPIVTFMNKLDRDIRDPIELMDEVEEVLNIKCAPITWPIGCGKEFKGVYHLLRDEVILYQGGMGHTIQDSRVIKGLDNPELDDAIGSYAADIRDEMELVVGASHEFDLELFLKGELTPVYFGTALGNFGVDHILDGIVEWAPIPQPRETETRDVQPEEEKFSGFVFKIQANMDPKHRDRVAFMRVCSGRYEQGMKMHHVRLGKDVNVSDALTFMAGDRNRAEAAYPGDIIGLHNHGTIRIGDTFTQGEKLRFTGVPNFAPEMFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLDSNDLIVGAVGVLQFEVVVGRLKTEYKVEAIYEAISVATARWVYCNDHKKLDEFKRKCSMNLALDGGDNLTYIAPTMVNLNLSMERYPDIEFAKTREN
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXCL7_PIG
Sequence: MSLRLGAISSCTTSSPFPVLQVLLPLSLLLTTLVPATMGAAKIEGRMAHVELRCLCLNTVSGIHPSNIQSLEVIRAGAHCAKVEVIATLKNDKKICLDPEAPRIKKIVQKIMEDGGSAA
What is the function of this protein?
Chemoattractant factor for neutrophils.
What are the official names of this protein?
Platelet basic protein, PBP, C-X-C motif chemokine 7, Small-inducible cytokine B7.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KAD_RUMCH
Sequence: MRIILLGAPGAGKGTQAKIISEKLNIPHVSTGDIFRANIKGNTPLGQKAKEYMDKGELVPDELTVEIVKDRLGNVDCVNGFILDGFPRTIPQAEYLDKVLVQMNINLDVALLIDVKDEDIIKRMSGRRVCTNCGATYNVVFNPTKVEGICDVCNSPVIQRADDAAETVLNRLETYHKQTQPLINYYEKAGKLKVAEGAGEVDETSKRVMKALGI
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURA_ALCBS
Sequence: MINKTLHTKHTLLGLLAMAVLMIPVWSQAKVQMLDRIVAVVNDGAIMASELDERINTIALQFQEKGQQLPSPAILREQVLDRMILERLQLQLAERAGIKVDEASLNEALAGIARQNDMSLEDFAATLREDGYSWTQFREQIRQDMVISRLQQRSVASRIQITDREVDRFLSSELGKQMFQEDFRLGHILIRVPSEARPQQISQARAKAKEIIERLEAGSDFQQLAIALSDGPNALEGGDLGWRPAAQWPTLFAENAINLKKGEFSQPLRSGAGFHILKMIDRKGGAEKVVTQYHVRHVLIKADALTSAEQAQQRAIRLHDEVAAGKRQFKETAAEFSDDPGSARNGGELGWVNKGEMVPEFEQVMLNTPVGELSPVFESQFGWHFLRVDDIRDADMSTEFRRMQATQALQKRRFEEELETWVQEKRSESYVDIRL
What is the function of this protein?
Chaperone involved in the correct folding and assembly of outer membrane proteins.  Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins.  May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
What are the official names of this protein?
Chaperone SurA, Peptidyl-prolyl cis-trans isomerase SurA, PPIase SurA, Rotamase SurA.
What are the subcellular locations of this protein?
Periplasm. Note=Is capable of associating with the outer membrane.
Protein: TAP2_HUMAN
Sequence: MRLPDLRPWTSLLLVDAALLWLLQGPLGTLLPQGLPGLWLEGTLRLGGLWGLLKLRGLLGFVGTLLLPLCLATPLTVSLRALVAGASRAPPARVASAPWSWLLVGYGAAGLSWSLWAVLSPPGAQEKEQDQVNNKVLMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVIDILGGDFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDLERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVIAHRLQTVQRAHQILVLQEGKLQKLAQL
What is the function of this protein?
ABC transporter associated with antigen processing.  In complex with TAP1 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules (PubMed:25656091, PubMed:25377891).  Uses the chemical energy of ATP to export peptides against the concentration gradient (PubMed:25377891).  During the transport cycle alternates between 'inward-facing' state with peptide binding site facing the cytosol to 'outward-facing' state with peptide binding site facing the ER lumen.  Peptide antigen binding to ATP-loaded TAP1-TAP2 induces a switch to hydrolysis-competent 'outward-facing' conformation ready for peptide loading onto nascent MHCI molecules.  Subsequently ATP hydrolysis resets the transporter to the 'inward facing' state for a new cycle (PubMed:25377891, PubMed:25656091, PubMed:11274390).  Typically transports intracellular peptide antigens of 8 to 13 amino acids that arise from cytosolic proteolysis via IFNG-induced immunoproteasome.  Binds peptides with free N- and C-termini, the first three and the C-terminal residues being critical.  Preferentially selects peptides having a highly hydrophobic residue at position 3 and hydrophobic or charged residues at the C-terminal anchor.  Proline at position 2 has the most destabilizing effect (PubMed:7500034, PubMed:9256420, PubMed:11274390).  As a component of the peptide loading complex (PLC), acts as a molecular scaffold essential for peptide-MHCI assembly and antigen presentation (PubMed:26611325, PubMed:1538751, PubMed:25377891).
What are the official names of this protein?
Antigen peptide transporter 2, APT2, ATP-binding cassette sub-family B member 3, Peptide supply factor 2, Peptide transporter PSF2, PSF-2, Peptide transporter TAP2, Peptide transporter involved in antigen processing 2, Really interesting new gene 11 protein, RING11.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
Protein: RS21_METCA
Sequence: MPSIKIRENEPFEIAIRRFKRACEKAGVLSEVRRREYYEKPTEERKRKAAAAIKRHLKKLSRERFALQNLRKGRPQQ
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: UBIC_KLEP3
Sequence: MSHPALTRLRALRYFAVMPSLAPPLSDWLLLEDSMTQRFEQQGKQVTVTLINEGYIEREALTDEAALLPDEPRYWLREIILNADGEPWLAGRTVVPESTLCGPELALQQLGQIPLGRYLFTSSTLTRDFIEIGRDAALWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_VIBC1
Sequence: MAKLNAYFGEYGGQYVPQILVPALEQLEQAFIDAQEDPEFRSEFMTLLQEYAGRPTALTLTRNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKNEIIAETGAGQHGVATALACALLGLKCRVYMGAKDVERQSPNVFRMKLMGAEVIPVHSGSATLKDACNEALRDWSATYEDAHYLLGTAAGPHPFPTIVRDFQRMIGEETKNQILAREGRLPDAVIACVGGGSNAIGMFADFIEEESVRLIGVEPAGKGIDTDQHGAPLKHGKTGIFFGMKAPLMQDPNGQVEESYSVSAGLDFPSVGPQHAHLNAIGRAEYDNVTDDEALEAFQEIARHEGIIPALESSHAVAHALRMARENPEKEQLLVVNLSGRGDKDIFTVHAILEEKGAI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: EFG_GEOKA
Sequence: MAREFSLEKTRNIGIMAHIDAGKTTTTERILFYTGRVHKIGEVHEGAATMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGAITVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYSVKTLHDRLQANAHPVQLPIGAEDQFSGIIDLVEMCAYHYHDELGKNIERIDIPEEYRDMAEEYHNKLIEAVAELDEELMMKYLEGEEITTEELKAAIRKATISVEFFPVFCGSAFKNKGVQLLLDGVVDYLPSPVDIPAIRGVVPDTEEEVTREASDDAPFAALAFKIMTDPYVGKLTFIRVYSGTLDSGSYVMNTTKGKRERIGRLLQMHANHRQEISKVYAGDIAAAVGLKDTTTGDTLCDEKHPVILESMQFPEPVISVAIEPKSKADQDKMSQALQKLQEEDPTFRAHTDPETGQTIISGMGELHLDIIVDRMRREFKVEANVGAPQVAYRETFRKSAQVEGKFIRQSGGRGQYGHVWIEFSPNERGKGFEFENAIVGGVVPKEYVPAVQAGLEEAMQNGVLAGYPVVDIKAKLFDGSYHDVDSSEMAFKIAASLALKNAATKCDPVLLEPIMKVEVVIPEEYLGDIMGDITSRRGRIEGMEARGNAQVVRAMVPMAEMFGYATSLRSNTQGRGTFSMVFDHYEEVPKNIADEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA7B_XENLA
Sequence: MSYDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGKEIVVLGVEKKSVAKLQDERTVRKICALDENVFMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKHYTDEAIETDDLTIKLVIKALLEVVQSGGKNIELAVMRRDQPLKILNPEEIERYVAEIEKEKEENEKKKQKKT
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-7-B, Proteasome subunit alpha 4-B.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NADK_THIDA
Sequence: MQIPFHTVGLVGKYDNQGMEASVRALAEFLRGRGHAVVLACQTAEHFGITDFPTRNLHDLATESDAVVVLGGDGTMLSIARELSAHGVPLIGINQGRLGFLTDITVDHMYDAVDEILSGQYVAEERILLKGQILRGGERVFEATAFNDVVVGKGGSGRLIDLEIAIDGEFVYSQRADGLVVTTPTGTTAYALSAGGPIVHPTLEAVALVPICPHTLSARPIVVSGRSRIELHLTYADDARVHFDGQHHFDLQSGDHVWITRANRPITLLHPHSYSYYDTLRQKLHWGKKL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_STRZJ
Sequence: MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKELQATLDKAEKTLVKVMQEDGTESDFE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_SHESW
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGAAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FBID_RHOE4
Sequence: MHAIVAVKSLRSAKSRLAGELDADARADLVLAMLHDTLATVAAVSAIDTVTVVTPDPTVAALAYSVGVTVYADPAPHISLTNGASPRAEETLNAALSAAAADIRAKRGVVDLVVLQADLPAMQPSELTEAVAAARSGGRSVVVDHHGTGTSALFACGESALDPRFGPESARGHANSGARPLNGQWPGLRTDVDTHADLDTVRALGVGPATLASLTRLKATPSNSR
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: ABHDB_XENTR
Sequence: MTLKLAVLRQIFQGSKGWHLWQHWRAFYSSSASGNGKLCCQTGTTDKNTHATRVVDLSYDLYDGSAPGPPLVLLHGLFGSKSNFQSIARALVRKTGRKVLTLDARNHGCSPHDDIMTYPAMSADVCQILHKLQITSCVLIGHSMGGKTAMTVALQEPKLVERFVSVDISPAATVPQTGFPHYIAAMQKVHLEGKIPRSTARRLAEEQLSSTVKEASIRQFLLTNLVQENGTFKWRVNLEVISQHLQDLLDFPEFQEPYPGPALFLGGANSPYISSENYPEIERLFPCANVEYIFGAGHWVHADKTHDFLNSICNFVESA
What are the official names of this protein?
Protein ABHD11, Alpha/beta hydrolase domain-containing protein 11, Abhydrolase domain-containing protein 11.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: RNPA_LISW6
Sequence: MKKKYRIKKNDDFQKVFRRGKSFANRQFVVYTLKQEGSNHFRIGLSVSKKIGNAVCRNRIKRYIRQSFHELEDQINPENEYIIIARKPAANMDFHEVKKSLIHVLKVGRVLKQKPNNSK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: NRDI_KLEP3
Sequence: MSLIVYFSSRSENTHRFVQRLGLPAVRIPLNEREHLQVDEPYILIVPSYGGGGTAGAVPRQAICFLNDVHNRQLIRGVIAAGNRNFGDAWGRAGEVIAQKCAVPYLYRFELMGTPDDIDNVRKGVSEFWQRQPQNV
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: LSRA_ECOLI
Sequence: MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLGGNGAGKSTLMKIIAGITPADSGTLEIEGNNYVRLTPVHAHQLGIYLVPQEPLLFPSLSIKENILFGLAKKQLSMQKMKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSRILILDEPTASLTPAETERLFSRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTIALSGKTSELSTDDIIQAITPAVREKSLSASQKLWLELPGNRPQHAAGTPVLTLENLTGEGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGRIMLNGKEINKLSTGERLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLERYRRALNIKFNQPEQAARTLSGGNQQKILIAKCLEASPQVLIVDEPTRGVDVSARNDIYQLLRSIAAQNVAVLLISSDLEEIELMADRVYVMHQGEITHSALTERDINVETIMRVAFGDSQRQEASC
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Autoinducer 2 import ATP-binding protein LsrA, AI-2 import ATP-binding protein LsrA, EGO10A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. AI-2 autoinducer porter (TC 3.A.1.2.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: QCRB_STRLI
Sequence: MSTAANEPSRSRGKAPAGERVADWADGRLGIYSLAKANMRKIFPDHWSFMLGEVCLYSFIIIILTGVYLTLFFHPSMAEVEYHGSYVPLQGQMMSEAYASTLDISFDVRGGLLIRQIHHWAALIFLAGMFVHMMRVFFTGAFRKPREVNWLFGFLLLVLGMFTGFTGYSLPDDLLSGTGIRFMEGAILSVPIVGTYISFFLFGGEFPGHDFVSRFYSIHILLLPGIMLGLLVGHLILVFYHKHTQFAGPGKTNKNVVGMPLLPVYTAKAGGFFFLVFGVISVVSAIATINPIWPSGPTGPTRSPPAPSRLVLGFSEGLIRVMPGWEINAWGHTLVLGVFVPLLIFPLVLAAIAVYPFIESWVTGYKREHYILDRPLLDRPRNAPTRTAFGVAWLTVYFVLLIGGGNDLWATHFHLSINAITWFVRIAFFVGPVVAFIATKRICLGLQRRDKDKVLHGRESAIIKRLPHGEFIEVHEPISQEQLHTLTAHEQYKPAEIGPTVDENGVERKVSGTQKLRAKLSESYYGEESQIPKPTVEEYKEITSGHGHH
What is the function of this protein?
Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.  The cytochrome b subunit contains two ubiquinol reactive sites: the oxidation (QP) site and the reduction (QN) site.
What are the official names of this protein?
Cytochrome bc1 complex cytochrome b subunit, Cytochrome bc1 reductase complex subunit QcrB, Ubiquinol--cytochrome c reductase cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.