PharMolix/UniProtQA huggingface dataset:
Protein: UTP9_YEAST
Sequence: MGSSLDLVASFSHDSTRFAFQASVAQKNNVDIYPLNETKDYVVNSSLVSHIDYETNDMKVSDVIFFGWCSDLIDTQSSNIKRKLDEDEGTGESSEQRCENFFVNGFPDGRIVVYSSNGKDIVNIIKNKKEILGADTDESDIWILDSDKVVKKLQYNNSKPLKTFTLVDGKDDEIVHFQILHQNGTLLVCIITKQMVYIVDPSKRRPSTKYSFEISDAVACEFSSDGKYLLIANNEELIAYDLKEDSKLIQSWPVQVKTLKTLDDLIMALTTDGKINNYKIGEADKVCSIVVNEDLEIIDFTPINSKQQVLISWLNVNEPNFESISLKEIETQGYITINKNEKNNADEADQKKLEEKEEEAQPEVQHEKKETETKINKKVSKSDQVEIANILSSHLEANSTEILDDLMSGSWTEPEIKKFILTKINTVDHLSKIFLTISKSITQNPWNEENLLPLWLKWLLTLKSGELNSIKDKHTKKNCKHLKSALRSSEEILPVLLGIQGRLEMLRRQAKLREDLAQLSMQEGEDDEIEVIEHSNVISNPLQDQASPVEKLEPDSIVYANGESDEFVDASEYKD
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 9, U3 snoRNA-associated protein 9, U three protein 9, U3 protein 9 required for transcription, t-UTP9.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Associated with ribosomal chromatin, even in the absence of transcription.
Protein: CF298_RAT
Sequence: MVVLHVKRGDESQFLLQAPGSTELEELTAQVTRVYNGRLKVHRLCTEIEELAEHGVFLPPNMQGLTDEQIEELKLKDEWGEKCVPSGGSVFTKDDIGRRNGHAPNEKMKQVLKKTVEEAKAMVSKKQVEAGVFVTMEMVKDALDQLRGAVMIVYPMGLPPYDPIRMEFENKEDLSGTQAALEVIQESEAQLWWAAKELRRTKKLSDYVGKNEKTKIIVKIQQRGQGAPAREPLISSEEHKQLMLFYHRRQEELKKLEENDDDSCLNSPWADNTALKRHFHGVKDIKWRPR
What is the function of this protein?
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly.  Seems to be important for initiation rather than maintenance of cilium motility.  Required for correct positioning of cilia at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway.  May suppress canonical Wnt signaling activity.
What are the official names of this protein?
Cilia- and flagella-associated protein 298, Protein kurly homolog.
What is the protein family that this protein belongs to?
Belongs to the CFAP298 family.
Protein: RUVA_PSEPG
Sequence: MIGRLRGTLAEKQPPHLIIDVNGVGYELEVPMTTLYRLPKVGEAVTVHTHLVVREDAHLLYGFAEKRERELFRELIRLNGVGPKLALALMSGLEVDELVRCVQAQDTSALVRVPGVGKKTAERLLVELKDRFKAWETSPAMFTLVSDGPLPVASESSAEADAVSALVSLGYKPQEASKAIAAIKDKAGLSSEELIRRSLKGMITK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LIPA_HYDCU
Sequence: MKARNESMSKGEYKTKSLKNRPDPTQPKLKKPSWIKAKLPSAKHIGRVKELKQVLREQGLNSVCEEASCPNLGECFGHGTATFMIMGHICTRKCPFCDVTHGRPNPLNQDEPRHLAKTIHAMNLNYVVITSVDRDDLRDGGATHFKNCTQAIRDKMPDIQIETLVPDFRGRLTVALDILAQQAPDVLNHNLETVPRLYEEARPGADYQASLDLLKRFKQMVPETKTKSGLMVGLGETFDEILQVMRDLRAHDVEMLTVGQYLQPSDFHLAVQRYWTPEEFKQLEQAGMEMGFTHVASGPMVRSSYHADLQAQGQFS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THAP7_HUMAN
Sequence: MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPASEYIYFCSKHFEEDCFELVGISGYHRLKEGAVPTIFESFSKLRRTTKTKGHSYPPGPAEVSRLRRCRKRCSEGRGPTTPFSPPPPADVTCFPVEEASAPATLPASPAGRLEPGLSSPFSDLLGPLGAQADEAGCSAQPSPERQPSPLEPRPVSPSAYMLRLPPPAGAYIQNEHSYQVGSALLWKRRAEAALDALDKAQRQLQACKRREQRLRLRLTKLQQERAREKRAQADARQTLKEHVQDFAMQLSSSMA
What is the function of this protein?
Chromatin-associated, histone tail-binding protein that represses transcription via recruitment of HDAC3 and nuclear hormone receptor corepressors.
What are the official names of this protein?
THAP domain-containing protein 7.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YR841_MIMIV
Sequence: MDQINVLINKLIYDTMNNITSLMLAVSNYEIHDNYDTVKSLIDCGFDVNAVDKHGKSVLMYAINIDSDKNINVIKLLIDHGADVNHVDSYQRSVLIHTCMYMEYGYNNKTISLLIDKGANINYICNGKNILMMIHKYLSEETFQEVFHLINNKIDINYNRSGIIRENILMRIIKKLDNKYSITTIKLLLEHGINIDHINIYGQTALMYACIYINGLKNIPIIKLLLEYGANINSKCTKGWSPLMSVFKNDIIDIKTIKFLVEKGAEINSKNCKNETMLYVFCKKLSTRIYGQACVKIFDFLIKKGISIDNPNDKGYTPLMAFIIKISEYNEYTEKFIKLLLDYGANINSKDIHGSSILNKVCCDVVSGSVSHCKIEIINTLIKYGADVNSTTLDHKTILMNLRYSIHSENYITVLEILLRNGANPNIYDEKYHKFPLLIDILNRGGELRIIKLMLQYNIDPNIVDNIGNNALLFVAKHYKKNERFSFLKLLLTYGASYNCVNKKGKSFSDYVLDKEVEYYSRTITNLSKDNRIMKNVIDSIPIKVPEKIYCLESFKMKIIRFKWNLCNRIDYDDEAIMNYLGTNDPVRLIQIIDESIKYDH
What are the official names of this protein?
Putative ankyrin repeat protein R841.
Protein: RUTE_ECO55
Sequence: MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGPTSANCSPARIVFIRTVEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFAGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL
What is the function of this protein?
May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted.
What are the official names of this protein?
Probable malonic semialdehyde reductase RutE.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family. HadB/RutE subfamily.
Protein: PARE_RICPR
Sequence: MSDLFSLNKEKKNKIVYTNYSAKDIEVLDGLEPVRKRPGMYIGGTDSNAMHHLVSEVLDNAMDEAVAGFASIIMIKMHQDHSITIFDNGRGIPIDNHPKFPDKSALEVILTTLHSGSKFSNNVYHTSGGLHGVGISVVNALSKHFKIKVYKQGKLYSQSYSKGAKLTDLISAEASKRLRGTSINFTPDPEIFSEKLHFNPKKIYEIARSKAYLYRGVSIEWECEVEVPSDIPKKALINFPNGLKDYLSSKISLDNLVIPEIFSGNIESTVDDIKLEWAICWQNNDTSAFMQSYCNTVPTPQGGTHEQGLKSAILRGLKAYSEMIGNKKAANLTIEDILETASIVLSIFIVEPSFQGQTKEKLVSNGVSKLVENIIKDHFDHFLSSDKVLATHLLEHVIAIAEFRRNKKNERNISRKSVTQKLRLPGKLADCTRTSAEGTELFIVEGDSAGGSAKQARNRETQAVLPLWGKVLNVASSTLEKIINNQAIQDLEIALACGSLKNYKKENLRYEKIIIMTDADVDGAHIASLLMTFFFLRMPKLVEEGHLYLAKPPLYRLTQSNKIYYACDEEEKIKLTYKLSKASKAKIEVGRFKGLGEMMPAQLKETTMHPEKRSLLKVTLEDVQNVDKIVDDLMGKKPEKRFQFIYEQALVKMDQIINKLDI
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 1 subfamily.
Protein: AROA_THIDA
Sequence: MEFLDLPGRSRASGTVRLPGSKSISNRVLLLAALAEGVTDVYDVLDSDDTRYMLAALQALGVGVEDRGDNHWRVTGVAGAFPARQAELFLGNAGTAFRPLTAVLALSGGDYVLDGVARMHERPIGDLVDALRQLGGRIDYRGTLGFPPLHVHPPQAGADVAHIRGNVSSQFLTGLLMALPLRRLRTRVEVVGELISKPYIEITLAMLRRFGVEVARDGWQAFSVAADACYRSPREIYVEGDASSASYFLAAGAIGGGPVRVEGVGRDSVQGDVGFADALAAMGARIAMGPNWIEACAPAQGRLKAIDLDCNAIPDAAMTLAVAALFADGTTTLRNIASWRVKETDRIAAMATELRKVGATVEEGDDFLRVTPPETLRAGAVIDTYDDHRMAMCLSLVSLGGVAVRINDPGCVAKTFPGYFNAFAEIAR
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_STRAW
Sequence: MTTTTDELVSYEDALASYDPVMGLEVHVELGTKTKMFCGCSTELGAEPNSQTCPTCLGMPGALPVVNAIGVESAIKIGLALHCEIAEWCRFARKNYFYPDMPKNFQTSQYDEPIAFNGYLDVQLEDGEVFRVEIERAHMEEDTGKSTHVGGATGRIHGASHSLLDYNRAGIPLIEIVTKPIEGAGERAPEVAKAYVAELRELIRALGVSEARMEMGQMRCDVNLSLRPHGREKFGTRSETKNVNSLRSVERAARFEIQRHAAVLNSGGTIIQETRHFHEDTGSTTSGRVKEEAEDYRYFPEPDLVPVAPSRAWVEELRAGLPEQPLARRNRLREEWGVNAHDMQSILNAGAIDPIVATIEAGADAASARKWWMGELARSANESGKALEDLPITPAQVARVAQLVVAGELNDKLARQVIEGVLAGEGTPDEVVEKRGLKVVSDEGALTAAVDEAIAGNPGVADKIRGGKVAAAGALVGAVMKATRGQADAARVKELILEKLGVSEG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: GRXS1_ORYSJ
Sequence: MARLVSTALMRGLVRSSRAPRVAAVSQPAIQQFRNYSPGLGGDSRGSGDSSSTRVAADPDTHQDFQPTSKSSNMSFDDIVAQDIKENPVLIYMKGFPESPMCGFSALAVKVLKLYDVPISARDILGDLKLKECVKAHTNWPTFPQIFIKGEFVGGSDIILDMHQKGQLKDVLGDIAQKHEQKESS
What is the function of this protein?
May only reduce GSH-thiol disulfides, but not protein disulfides.
What are the official names of this protein?
Monothiol glutaredoxin-S1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CGFS subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DOPR2_CAEEL
Sequence: MEAGETWNVSLEWPPPSLDLSTITQTPSTIVGSGIPLNYAGLSLIVIPLITLLGNLLVIISVLRYRALQSAINFLILGLAVADLLVAIIVMPYAVYVYVTNGDWYLGNLMCDIYMASDVCCSTASILLLAVISFDRYRAVSLPIQYSRQSQNVKRVWTLIAVIWLVSLTLASPMVFGVNVRPPDANPYECRFYNAEFSILSSMISFVIPCFLVLFVYIRIIIALKKREKAAKMRREKNTIAHGLTMRPDTGEEQVDEEAAGRIVAGPVVNVMMAALPSMTRRMRQFERHRRAIELAGDEEWEEDELDVMDECCGGDDAGDDDDDYHADNGQGVVEASAPRTTSMLRRIINAASVGTANSTAQSVASASGMPAFFAQNISTTSPSSSSCARTTTTTSAIPKASGDLPLPMLLNEREFGNSSTPRSSLESLSENVNVITNDFVSENCTTFSRRSSYADDSQPTSSQTSSGDGRSYSIKGQKRFRNLSRNYSTKHHRKVVKVNRGNSRNNSRTASITNQSDDALIPAIIRTISRKSPRLFRRDKTDIKKHSMILANPITEPPKEYRRVSMPIHPTNSQTETETISASRDIENLPTTTISRSTTANSAELLGSPDDFEKFPALITETVLEDVLAETREGCFMQPTVSFALTVREMEGNALNNLKGCSVESSRRVSQVDPPLAIQILTRPSLPHLDLQRMDSIGTTCSSKTRADSLRSVDSKGSKKSNRNGIAVKLVKRAIKHEHSLKRKVSKAQRKEKRATKTLGVVVGVFLVCWVPFFVINILNAVCILLNKDSCQVGYDLFFYCTWIGYMNSFMNPIIYTIFNTEFRRAFKSIIFGRNSTRHHFSNKQAHV
What is the function of this protein?
G-protein coupled receptor which binds to the neurotransmitter dopamine with high affinity leading to the activation of an associated G-protein and downstream signaling pathways (PubMed:12887685).  Couples to G-proteins to inhibit adenylate cyclase (AC) activity and cAMP production (PubMed:12887685).
What are the official names of this protein?
Dopamine receptor 2, Dopamine D2-like receptor dop-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VASN_HUMAN
Sequence: MCSRVPLLLPLLLLLALGPGVQGCPSGCQCSQPQTVFCTARQGTTVPRDVPPDTVGLYVFENGITMLDAGSFAGLPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGLRRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPLRLPRLLLLDLSHNSLLALEPGILDTANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVPPVIRGLRGLTRLRLAGNTRIAQLRPEDLAGLAALQELDVSNLSLQALPGDLSGLFPRLRLLAAARNPFNCVCPLSWFGPWVRESHVTLASPEETRCHFPPKNAGRLLLELDYADFGCPATTTTATVPTTRPVVREPTALSSSLAPTWLSPTEPATEAPSPPSTAPPTVGPVPQPQDCPPSTCLNGGTCHLGTRHHLACLCPEGFTGLYCESQMGQGTRPSPTPVTPRPPRSLTLGIEPVSPTSLRVGLQRYLQGSSVQLRSLRLTYRNLSGPDKRLVTLRLPASLAEYTVTQLRPNATYSVCVMPLGPGRVPEGEEACGEAHTPPAVHSNHAPVTQAREGNLPLLIAPALAAVLLAALAAVGAAYCVRRGRAMAAAAQDKGQVGPGAGPLELEGVKVPLEPGPKATEGGGEALPSGSECEVPLMGFPGPGLQSPLHAKPYI
What is the function of this protein?
May act as an inhibitor of TGF-beta signaling.
What are the official names of this protein?
Vasorin, Protein slit-like 2.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Secreted.
Protein: VE1_HPV31
Sequence: MADPAGTDGEGTGCNGWFYVEAVIDRQTGDNISEDENEDSSDTGEDMVDFIDNCNVYNNQAEAETAQALFHAQEAEEHAEAVQVLKRKYVGSPLSDISSCVDYNISPRLKAICIENNSKTAKRRLFELPDSGYGNTEVETQQMVQVEEQQTTLSCNGSDGTHSERENETPTRNILQVLKTSNGKAAMLGKFKELYGVSFMELIRPFQSNKSTCTDWCVAAFGVTGTVAEGFKTLLQPYCLYCHLQSLACSWGMVMLMLVRFKCAKNRITIEKLLEKLLCISTNCMLIQPPKLRSTAAALYWYRTGMSNISDVYGETPEWIERQTVLQHSFNDTTFDLSQMVQWAYDNDVMDDSEIAYKYAQLADSDSNACAFLKSNSQAKIVKDCGTMCRHYKRAEKRQMSMGQWIKSRCDKVSDEGDWRDIVKFLRYQQIEFVSFLSALKLFLKGVPKKNCILIHGAPNTGKSYFGMSLISFLQGCIISYANSKSHFWLQPLADAKIGMLDDATTPCWHYIDNYLRNALDGNPVSIDVKHKALMQLKCPPLLITSNINAGKDDRWPYLHSRLVVFTFPNPFPFDKNGNPVYELSDKNWKSFFSRTWCRLNLHEEEDKENDGDSFSTFKCVSGQNIRTL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MAM_FAEPA
Sequence: MMMPANYSVIAENEMTYVNGGANFIDAIGAVTAPIWTLDNVKTFNTNIVTLVGNTFLQSTINRTIGVLFSGNTTWKEVGNIGKNLFGTNVKGNPIEKNNFGDYAMNALGIAAAVYNLGVAPTKNTVKETEVKFTV
What is the function of this protein?
Plays an anti-inflammatory role in the mammalian intestine.  The supernatant of this bacteria, or 2 purified fractions containing peptides derived from this protein, exerts inhibitory effects on IL1-beta-induced IL-8 secretion in intestinal epithelial CaCO-2 cells (PubMed:18936492, PubMed:26045134).  Mice fed this bacterium suffer less severe symptoms in 2,4,6-trinitrobenzenesulphonic acid (TNBS)-induced colitis (PubMed:18936492).  Expression in human epithelial cell lines (HEK293T, HT29) shows a decrease in activation of NF-kappa-B induced by Carma-1 (CARD11) or lipopolysaccharide.  The decrease occurs in a MAM-dose dependent manner.  Also inhibits activation induced by IKBKB in HEK293T cells.  Expression in cell lines has no effect on the STAT3 pathway.  L. lactis expressing the protein offers a protective effect to mice in dinitrobenzene sulfonic acid (DNBS) and dextran sodium sulfate (DSS)-induced colitis (PubMed:26045134, PubMed:28203226).  It may play a role in maintaining the intestinal barrier, which is important in diabetes mellitus (Probable).
What are the official names of this protein?
Microbial anti-inflammatory molecule, MAM.
What are the subcellular locations of this protein?
Secreted. Note=Detected in cell supernatants as a mixture of peptides corresponding to residues 49-68; 50-68; 51-68; 52-68; 53-68; 69-111 and 112-135. When transfected in human cells surrounds the nucleus and colocalizes with IKBKB.
Protein: RL23_CANLF
Sequence: MSKRGRGGSSGAKFRISLGLPVGAVINCADNTGAKNLYIISVKGIKGRLNRLPAAGVGDMVMATVKKGKPXLRKKVHPAVVIRQRKSYRRKDGVFLYFEDNAGVIVNNKGEMKGSAITGPVXKECADLWPXIASNAGSIA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3839_YERPE
Sequence: MPRHIYIATTTDTKGQELAYVSELIQATGLTTVTVDLSTKESQRDSGADICAETVAGYHPDGRQAVFCGDRGQAINAMAIAFERFMVSRVDVAALLGMGGSGGTALITPAMQRLPIGIPKLMVSTMASGDVSGYIGASDIAMMYSVTDIAGLNRISRRVLSNAAHQVAGAVYFAQEASPVDDKPALGLTMFGVTTPCIQAVSAELSDEYDCLVFHATGSGGKAMEKLAESGLLAGVLDLTTTEVCDLLFDGVLACGPERFDAIAHTHIPYVGSCGALDMVNFGSPATIPAKYADRLFYKHNAQVTLMRTTEQENIEMARWIGEKLNRCQGEVRFLIPEGGFSALDAPGQPFWDEKALTAFIRTLEETVIQTDKRRVVHYPFNINDPLFAQAAIENFKEIVNRPSH
What are the official names of this protein?
UPF0261 protein YPO3839/y0391/YP_3209.
What is the protein family that this protein belongs to?
Belongs to the UPF0261 family.
Protein: NANH_BACFR
Sequence: MKKAVILFSLFCFLCAIPVVQAADTIFVRETRIPILIERQDNVLFYLRLDAKESQTLNDVVLNLGEGVNLSEIQSIKLYYGGTEALQDSGKKRFAPVGYISSNTPGKTLAANPSYSIKKSEVTNPGNQVVLKGDQKLFPGINYFWISLQMKPGTSLTSKVTADIASITLDGKKALLDVVSENGIEHRMGVGVRHAGDDNSAAFRIPGLVTTNKGTLLGVYDVRYNSSVDLQEHVDVGLSRSTDGGKTWEKMRLPLAFGEFGGLPAGQNGVGDPSILVDTKTNNVWVVAAWTHGMGNQRAWWSSHPGMDMNHTAQLVLAKSTDDGKTWSAPINITEQVKDPSWYFLLQGPGRGITMSDGTLVFPTQFIDSTRVPNAGIMYSKDGGKNWKMHNYARTNTTEAQVAEVEPGVLMLNMRDNRGGSRAVAITKDLGKTWTEHESSRKALPESVCMASLISVKAKDNVLGKDLLIFSNPNTTKGRYNTTIKISLDGGVTWSPEHQLLLDEGNNWGYSCLSMIDKETIGILYESSVAHMTFQAVKLKDIIK
What is the function of this protein?
Sialidases have been suggested to be pathogenic factors in microbial infections.
What are the official names of this protein?
Sialidase, Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y3108_BRUME
Sequence: MKPKISFNNVVMRYGGFLALDRLNLDIADGEFVTVVGPSGCGKSTAMNIADGLLQPSGGGILVGDKPVTGPGPERGVIFQQYALFPWLTVRQNVEFGLTDFADALPKALSGGMKQRCAIARAYAAAPEILLMDEPFGALDALTRVHMQDQLLDAWSRERRTVMFITHDVDEAVYLANRVIVMAARPGRLDQIIPVDLPYPRTEAIRLSPEFAAIRNRVWHAVYHQQPQTDQQSSHGQ
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Putative ATP-binding protein BMEII0108.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FPG_CARHZ
Sequence: MPELPEVETIKRTLAPKILGKTIYRVEVYLPKIIKNVSVEEFTRRVVGKEIVALKRRGKYLLIDLSGKETVTVHLRMTGKLLILPKGSPKDKHTHAIFDLGDLELHFNDIRQFGGFSFEMPEIGPEPLEDEFTPEYLKTKLKASQKNLKAVLLDQKIIAGIGNIYADEILFEAGLSPKRIAASLSEDEAEELFKAIRKILALGIEYRGTSIRDYVDAENQQGSFQRLLKVYGKNGSLCVRCNNVLIRERHAGRSTHYCPHCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: MYO1A_CHICK
Sequence: MEATTSLLDAAAVGDLVMLDPLSEESLLRTLQERFSRGEIYTYIGEVVISVNPYKPLPIYTPEKVEEYHNCNFFAVKPHIYAIADDAYRSLRDRDRDQCILITGESGAGKTEASKLVMSYVAAVSSKGEEVDKVKEQLLQSNPVLEAFGNAKTIRNDNSSRFGKYMDVEFDFKGDPLGGVISNYLLEKSRIVRHVKGERNFHIFYQLLAGGSAQLLQQLKLRPDCSHYGYLNHEKSVLPGMDDAANFRAMQDAMAIIGFAPAEVTALLEVTAVVLKLGNVKLSSCFQASGMEASSITEPRELQEISQLIGLDPSTLEQALCSRTVKVRDESVLTALSVSQGYYGRDALAKNIYSRLFDWLVNRINTSIQVKPGKQRKVMGVLDIYGFEIFQDNGFEQFIINYCNEKLQQIFILMTLKEEQEEYVREGIQWTPVEFFDNSIICDLIENSKVGILAMLDEECLRPGTVNEDTFITKLNQIFASHKRYESKETLNAKHVTDVSLPLRCFRIHHYAGKVTYNVTGFIEKNNDLLFRDLSQAMWAARHTLLRSLFPEGDPQRPSLKLPPTTGSQFKASVATLMKNLYSKNPNYIRCIKPNDTKTAMLFTPDLVLAQVRYLGLMENVRVRRAGYAFRQLYQPFLERYKMLSRKTWPRWTGGDREGAEVLLAELKFPPEELAYGHTKIFIRSPRTLFDLEKRRQQRVAELATLIQKMFRGWCCRKRYQLMRKSQILISAWFRGHMQRNRYKQMKRSVLLLQAYARGWKTRRMYRRYFRSDACTRLSNFIYRRMVQKYLMGLQKNLPPMAVLDRTWPPAPYKFLSDANQELKSIFYRWKCKKYREQLTPQQRAMLQAKLCASELFKDKKALYAQSLQQPFRGEYLGLTQNRKYQKLQAVAKDKLVMAEAVQKVNRANGKTVPRLLLLTTEHLVLADPKAAQPKMVLSLCDIQGASVSRFSDGLLALHLKETSTAGGKGDLLLVSPHLIELVTRLHQTLMDATAQALPLSIADQFSTRFPKGDVAVTVVESAKGGGDVPVCKKRGSHKMEILVH
What is the function of this protein?
Could play an important role in morphogenesis and function of intestinal microvilli.
What are the official names of this protein?
Unconventional myosin-Ia, Brush border myosin I, BBM-I, BBMI, Myosin I heavy chain, MIHC.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: RUVB_BRUME
Sequence: MSDRNPLIDADRRADEDNTLRPQTLDDFVGQAAARANLKVFIEAAKVRGEALDHVLFVGPPGLGKTTLAQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPVRLNFYTVEELEYIVRRGARIMQMGISSDGAREVARRSRGTPRIVGRLLRRVRDFALVAGADIIDRRIADEALSRLEVDNRGLDQLDRRYLNIIARNFGGGPVGIETIAAGLSEPRDAIEDIIEPYLIQQGFLQRTPRGRVLTAVAWQHLGLPAPAEIIQQSQYGLFMEDE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CY24A_MOUSE
Sequence: MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIAAGVLICLLEYPRGKRKKGSTMERCGQKYLTSVVKLFGPLTRNYYVRAALHFLLSVPAGFLLATILGTVCLAIASVIYLLAAIRGEQWTPIEPKPKERPQVGGTIKQPPTNPPPRPPAEVRKKPSEGEEEAASAGGPQVNPMPVTDEVV
What is the function of this protein?
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.  Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
What are the official names of this protein?
Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox.
What is the protein family that this protein belongs to?
Belongs to the p22phox family.
What are the subcellular locations of this protein?
Cell membrane. Note=As unassembled monomer may localize to the endoplasmic reticulum.