PharMolix/UniProtQA huggingface dataset:
Protein: PSPC_RABIT
Sequence: MDMGSKEALMESPPDYSAAPRGRFGIPCCPVHLKRLLIVVVVVVLVVVVIVGALLMGLHMSQKHTEMVLEMSIGAPEVQQRLALSEWAGTTATFPIGSTGIVTCDYQRLLIAYKPAPGTCCYLMKMAPDSIPSLEALARKFQANPAEPPTQRGQDKGPAAGPASSGGELAFLGAAVSTLCGEVPLIYI
What is the function of this protein?
Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
What are the official names of this protein?
Pulmonary surfactant-associated protein C, SP-C, Pulmonary surfactant-associated proteolipid SPL(Val).
What are the subcellular locations of this protein?
Secreted, extracellular space, surface film.
Protein: METE_RHOPA
Sequence: MSSHTVSTSLAVATLGTPRIGPRRELKSALESFWAGKSTEADLLKVAAALRAANWARQSARGVSVIPSNDFSLYDQVLDTSVMVGAIPEIYGWRGGPVSLATYFAMARGTQAEIAGHGCANGHHHGDSTPQGVPAQEMTKWFDTNYHYMVPEFSAGQSFQLASVKPLEEYREAKALGYDTRPVLLGPVTYLKLGKSADAGLDVLSLLPKLVPVYIEILGRLAAAGAKWVQLDEPALVLDLDDRERLAFRDAYGQIARELPHLDIMLTTYFGGLGDNLDTALALPIAGLHLDLVRAPKQINAVIAKGPKDLVLSLGVVDGRNIWRADLPDLLDRVEPIVQQRGAERVQLAPSCSLLHVPVDLELETGLDPDLKSWLSFSLQKMGELSTLSRALSGDRAAVQDQLSASAKAAATRRKSPKVHDMAVSSRAAAVTPAMTQRNSGFAARATLQHQRLQLPAFPTTTIGSFPQTAQIRQARAAHAKGAISDADYNTFLRGETARAIQWQEKVGLDVLVHGEFERNDMVQYFGEQLSGFAFTKEGWVQSYGSRCVRPPILFGDVSRPKPMTVGWWKYAQSLTGRPMKGMLTGPVTILNWSFVRDDVPRSTACLQIALAIRDEVGDLEQAGATMIQIDEAALREGLPLRRSEWKGYLDWAVECFRLCSSGVKDETQIHTHMCYSEFNDIIDAIAAMDADVISIETSRSKMELLDAFKTYKYPNEIGPGVYDIHSPRVPSVEEMTTLLQLARQRLSDGQLWVNPDCGLKTRGWDEVQGALVNMVEAARQIRQVSAG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RL24_BACAH
Sequence: MHVKKGDKVQVITGKDKGKQGVILVAFPKQNRVIVEGVNIVKKHSKPSQLNPQGGIITKEAPIHVSNVMILDPKTGEPTRVGFKVEDGKKVRIAKKSGELLDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: VATC1_MACFA
Sequence: MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPVNFQAMLLQPNKKTLKKLREVLHELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit C 1, V-ATPase subunit C 1, Vacuolar proton pump subunit C 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase C subunit family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: AROE_METCA
Sequence: MTQPDRYAVFGHPIEHSQSPRIHALFAAQTGQDLIYTAEDVPPDRFESCVRAFFDGGGRGLNCTIPLKEMAWLLADSRSGRAKRARAVNTLLLRADGSIFGDNTDGIGLLRDLRDNLGLNLAGTKILILGAGGATRGILAPLLAERPDRLVIANRTVATAETLTVEFGDLGPVEGCGFAALAGRRFDLIINATAASLSGELPPLPADILAPGGSCYDLAYAAEPTPFVRWGQEKQAVVSADGIGMLVEQAAEAFLLWRGVRPQTRPVIETLEAERRTAK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MADL2_XENLA
Sequence: MDSSGGAYLNVDAIWSKVGFVRLLQMLFGCTTFSLVLHRAGFSAAYGTFCVFVWAFCFALTILIVTCELTRLQSCLRSISWGNFTAAYAMLATLMTLTAAVIYPMYFTSLNCSSSDCSTKYFRLAVSVCAALLFVTYAVEVFLTRAKPGQPCSYMATASGLLKVVQAFVACVIFGALASESQYKKFVATQWCVAVYSFCFGVTMVVVILNITGRALSLCCPFERFVVIYTVLAILMYISAAVIWPVYFFDSKYGSAKRPSRCTWGQCPWDSQLAVTIFTHINLILYIADLIYTQRLRIVAQR
What are the official names of this protein?
Myeloid-associated differentiation marker-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the MAL family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYA_LAWIP
Sequence: MLTVNDIRQKFLGYFKNYNHQEIPSSSLIPRDDPSLLFTNAGMVQFKKVFTGQETRNYLRATTAQKCLRVGGKHNDLENVGRTARHHTFFEMLGNFSFGDYFKKEAIQFAWAFITEELNLSKEFLYITIYKDDDDAYDIWVNTIGVEPSRIYRMGEKDNFWSMGDTGPCGPCSEIHFDQGETFCCGDNCGIGSCDCDRFLEIWNLVFMQYEQLPSGERVILPKPSIDTGMGLERIVAICQQKSSNYDTDLFQPIIQYMASIAGVHYKKHEETDIALRVIADHSRAIAFMIADGILPSNEGRGYVLRRLIRRAFRFGKQIGMNQPFLYKTVNKVVELMGDIYTELYSRSEFMSRVVFDEEERFSITLDKGLILLEAELNALKEKNTKELPGDIAFKLYDTYGFPLDIINDIASKKHFAVDEANFQHLMQEQKERARSQWKGSGEKRIEACFQTLLEDGMQSEFIGYENLSGTGRIVALLDIDGLPIEELPTKSSGYVITDMTPFYGTSGGQTGDIGILSTITGKTQVVDTLKPATNLIVHVVTVTSGTILLDQEALLVVSESERLDTARNHTCTHILQSVLQKILGDHVRQAGSLVSPTRLRFDFTHIAPLTEEEIHAIELQVNTIIMANLPLRVEFMDQQSALEKGAMALFEEKYGNIVRVVTIGSENQTASIELCGGTHLTSTGQAGCFIIVSETGIAAGVRRIEAITGRNTLAYIKEYQKELSTTAAILKTKPEKVVEKVTSILSENKNLQKTVDTLESSSLSNQGKHLLDNLTRINNIDVLTANLKNFSLKALRDIMDDIRSKLSSGIVCLASTEGTKVHLLLYVSKDLHHNFTASELIKKIVVPIHGAGGGRPDQAQAGGTNPSGLSETFELLKNILEDQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA76B_XENTR
Sequence: MASALYACTKCHQRYPFEELSQGQQLCKECRIAHPIVKCTYCRSEFQQESKTNTICKKCAQNVKQFGTPKPCQYCNIIAAFIGTKCQRCTNSEKKYGPPQTCEQCKQQCAFDRKEEGRRKVDGKLLCWLCTLSYKRVLQKTKEQRKSLGSTHSNSSSSSLTEKDQHHSKHHHHHHHHHRHSSSHHKISSLSPEPEQGIWKQSHKSSTVIQNETPKKKPKLEFKPSNGDSSSINQSTDSGGTDNFVLISQLKEEVMSLKRLLQQRDQTILEKDKKLTELKADFQYQENNLRTKMNGMDKAHKDFVEQLQGKNRELLKQVAALSKGKKFDKSGSILTSP
What are the official names of this protein?
Protein FAM76B.
What is the protein family that this protein belongs to?
Belongs to the FAM76 family.
Protein: KGUA_CHLPN
Sequence: MNKILVDSPFSPDHQKCCPKLFTISAPAGVGKTTLVRMLEQEFSSAFAETISVTTRKPREGEVPGKDYHFVSHEEFQRLLDRQALLEWVFLFGECYGTSMLEIERIWSLGKHAVAVIDIQGALFIRSRMPSVSIFIAPPSQEELERRLASRGSEEGSQRKERLEHSLIELAAANQFDYVIINDDLNQAYRVLKSIFIAEEHRNIL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_SHEFN
Sequence: MAKQIQAIRGMNDILPTQSPLWQKVEAVLRSSVSAFGYSEIRTPIVESTDLFKRSIGEVTDIVEKEMYTFEDRNSDSLTLRPEGTASTVRAGNEHGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQFGVEVYGIGSADIDAEVLMLSARLWDLLGIKEHVALELNTLGDPAERAAYRDALIAFLEQHKDKLDEDSQRRMYSNPLRVLDSKDPQVQAILGDAPALMDYLGEDSKTHFSTLCELLDAVGIQYTINPRLVRGLDYYNRTVFEWVTTSLGSQGTVLAGGRYDGLVGQLGGKDTPAVGFAMGLERIVLLLETLELTSDIAPEVDVYVTAMGENCVVEAIKVAQELRQQLPTLKVMSHCGGGNFKKQMKRADKSGAQFALIIGENEIANNQVAIKPLRTNNEQQLVTRSELVAKIAELI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIXB_SALTI
Sequence: MNKFSSVWVFSDTPSRLPELMSGAQAVGEKVNAFVLNEADSATACHLGADHVWLLSGKPEDRMIEDYAAAMAETIRQHSEGGAVLLPNTRRGKLLAAKLGYRLSAAVSNDASDVSLQDGKAAVKHMVYGGLAIGAETIASPFAVITLSSGTFDAQQPDASRSGEMHTVQWQAPATAVTRTATQARQSNSVDLDKARLVVSVGRGIGSKENISLAEALCQTIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANGAQTIFAINKDKNAPIFQYADFGIVGDALKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: DBP4_SCLS1
Sequence: MAPPSVGRKSKNISKGKVDARTLKRKRVEEDLEKLQKSVDELDAKAEIKNFSELPLSGPTSSGLEASHFKTLTDVQSKAVPLALKGKDILGAAKTGSGKTLAFLVPVLENLYRQKWTELDGLGALIISPTRELAIQIFEVLRKIGRYHTFSAGLIIGGRSLQEERERLGRMNILVCTPGRMLQHMDQTAAFDVDNLQMLVLDEADRIMDMGFQTSVDAILEHLPKQRQTMLFSATQTKKVSDLARLSLKEPEYVAVHEAASSATPTTLQQHYCVVPLPEKLNTLFGFIRANLKAKIIVFMSSGKQVRFVYESLRHLQPGIPLLHLHGRQKQTARLDITSKFSSSKNSCIFATDVVARGLDFPAVDWVIQLDCPEDADTYIHRVGRTARYGKVGRAVLFLDPSEEEGMLKRLEHKKVPIQKINIRPNKTQDIKNQLQNMCFQDPELKYLGQKAFVSYAKSVFLQKDKEIFNINDIDLEGYASSIGLPGAPKIKFQKGNDAKNVKNAPRAAIESSDEDSETEKKPKKKDEVRTKYDRMFERRNQDVLSGHYSKMIADDTPMKDVDGTADADEDNDFLSVKRVLPVDNDDTSDDEDDDDDDDDDDDDVAATGPLGKVIEGISKDPIVIDSKRKEKLLKSKKKLLKLKDRGTKLVFDEEGNPHQVYELQDEEDFRAKGTAEEQRAKFLEEEAERVREADLLDKQTAKDKKREKREKRKAREAALDDDDEEALELVDAGDDEDPMALLKSLPLPEDEEDEDSTARPAKRPKKWFEDDSDDERKVAKRKGRVIEAADEPETLEDLEALAAGLLN
What is the function of this protein?
ATP-dependent RNA helicase required for ribosome biogenesis.  Involved in the release of U14 snoRNA in pre-ribosomal complexes.  Required for pre-rRNA cleavage at site A2 (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp4.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX10/DBP4 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FIBIN_HUMAN
Sequence: MVFLKFFCMSFFCHLCQGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDHRRCSQGEGSQVGSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLDISVGLRDKYELLALTIRSHGTRLGRLKNDYLKV
What are the official names of this protein?
Fin bud initiation factor homolog.
What is the protein family that this protein belongs to?
Belongs to the FIBIN family.
What are the subcellular locations of this protein?
Secreted. Golgi apparatus. Endoplasmic reticulum.
Protein: RL3_PARUW
Sequence: MLNSGSLIWLRIDYMALTMMGKKRGMIQLFDEKGNAIVCTVIQAEPNVITQIKTKETDGYTALQLGFEKVTGKTQHTIEARTGKPRLGHFKKAGVESRRFLVESRLDSTEEYTLGQEISVDTFNGIEFVDATAISKGKGYQGVMKRHNFAGGPASHGSGHHRHAGSTGMRSTPGRGLPGGKKAGQMGNERVTVQNLRIVKVDSENHVIVVKGQVPGPRNGLVYITQAKKLAKKKS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL3_ECOSE
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NADE_ARCFU
Sequence: MNFEKVVERICDFIRGVVSSSGSTGVVLGLSGGVDSATVAYLCVRALGSERVFALIMPETGVTPEQDVEDAINVAESLGMEYKLIEINDIVRVFKEKAGEGSKIAEANLKPRIRMVLNYYHANSMNRLVAGTGNKSELMVGYFTKYGDGGVDFLPIGDLYKTEVFQLAAYLGVPRRIIEKKPSARLWPGQTDEEEMGISYAELDEILKLIEKGERRDDEKFRRVVQMVERSRHKREMPPVARVRDLL
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: LEXA2_NOCFA
Sequence: MSRTDDTGEESGVAVDPALNGADLTVRQRKVLEVIRTSVSERGYPPSIREIGDAVGLTSTSSVAHQLRALERKGYLRRDPNRPRAVDVRGLDEAVRAVTALPGAALEEPDTLAEDTGRPTPTFVPVLGRIAAGGPILAEQAVEDVFPLPRELVGDGSLFLLRVVGQSMVDAAICDGDWVVVRQQNVAENGDIVAAMIDGEATVKTFKRTGKDVWLMPHNPLFEPIPGNDARILGKVVTVIRKI
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: YQIB_ECOL6
Sequence: MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQYRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARYDYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY
What are the official names of this protein?
Uncharacterized protein YqiB.
Protein: ISPH_CHLPN
Sequence: MRKLILCNPRGFCSGVVRAIQVVEVALEKWGAPIYVKHEIVHNRHVVNALRAKGAIFVEELVDVPEGERVIYSAHGIPPSVRAEAKARKLIDIDATCGLVTKVHSAAKLYASKGYKIILIGHKKHVEVIGIVGEVPEHITVVEKVADVEALPFSSDTPLFYITQTTLSLDDVQEISSALLKRYPSIITLPSSSICYATTNRQKALRSVLSRVNYVYVVGDVNSSNSNRLREVALRRGVPADLINNPEDIDTNIVNHSGDIAMTAGASTPEDVVQACIRKLSSLIPGLQVENDIFAVEDVVFQLPKELRCS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: NAAA_CAVPO
Sequence: MRSPGIVLLLLLLLLLPPGAAPCPADLCPAPPRVNVSLDAAPAARWLPVLRLFDPGLLRAAVARIVGDRVPKWRDVIGKLVAEMESFLPQPYTKEIRGISDFLNLSLADGFIVNLAYEASAFCTSVVAQDSRGHIYHGRNLDYPFGDLLRKMTVDVQFLKNGQIAFTGTTFIGYVGLWTGQSPYKFTVSGDERDKGWWWENMIAALFQGHSPVSWLIRTTLSESEDFEASVYKLAKTPLIADVYYIVGGTAPGEGVVVTRNRGGPADIWPLDPLNGAWFRVETNYDHWKPVPKSDDRRTPAIKALNATGQANLSLEALFQVLSVVPVCNKITVYTTVMSAATPDKYMTRIRNLS
What is the function of this protein?
Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-stearoylethanolamine > N-oleoylethanolamine > N-linoleoylethanolamine > N-arachidonoylethanolamine.
What are the official names of this protein?
N-acylethanolamine-hydrolyzing acid amidase, Acylsphingosine deacylase NAAA.
What is the protein family that this protein belongs to?
Belongs to the acid ceramidase family.
What are the subcellular locations of this protein?
Lysosome. Membrane; Peripheral membrane protein.
Protein: KPYK_STAAM
Sequence: MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
What are the official names of this protein?
Pyruvate kinase, PK.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PEP-utilizing enzyme family.
Protein: VL2_HPV63
Sequence: MLRVRKRRAAPQDIYPACKVANNCPPDIQNKIEQTTVADKILQYGSLGIFLGGLGIGTGKGGGGRYGYTPLGDSGAVRVGGRSTPVRPTVPVETVGPRDILPIDSLDPLGPSVIELEDIPATTVEVVAEVHPISDTPQIPAPTTDESSSAVLHIPQESPAARTITRSQYNNPLFRITASADIASGEASASDNIFIDVDTPGQIVGQEIPLVNFDMGPISTEGELETEFTTSTPRTTQVQERPTRFYNRRYYEQVPVTAPEFITRPASLVTFENPAFERSVSLIFEQDLEDILNAPDQDFRDIVYLSRPTYSRAPDGRMRLSRLGRRATISTRSGVTIGAQSHFYMDISSISSNDGIELQTLGEASGETVVQSSLAASDPIEAEHSFIEPAPSIDSYDIVSLQSETYSDEHLLDMYEPVGSSLQLQISDVRGRPTVIDIPFRPRRPPLGPINAGVDIYSPTASVGSPTINPTDLDIPLIIIHLDNSTGDYDLHPSLRKRRKLVHI
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: KU_BACHK
Sequence: MHTVWKGALSLGLLNIGIKLYSAVDENDIKFLSLHKECLTPIKYKKFAPDCTDEEVDDKDIVKAYEYAPHKYIIMDEKELSALQKAHEPRSIRIISFIQNNEIDSVLYDRSYFIGPTPGHEKSYLLLKEALERTNKLGLIHISIRKKQHLAIIRNFEDGLMLQTIHYPNEIRDITNIPNLPSNENYPIQKQELTAAINLIHHLTNPFEQELYTDEYKEALTELIENKIEEQAKTESISPAPNIINIMETLQASIEQAKIKRDNKTEKEAK
What is the function of this protein?
With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity.  Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA.  Recruits and stimulates the ligase activity of LigD.
What are the official names of this protein?
Non-homologous end joining protein Ku.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic Ku family.
Protein: ATPG_TRICV
Sequence: MKFFCVAGLLASAAAFQAQPAAFTTYSPAVGGATSNVFSESSSPAHRNRRATIVMDGKANAIRDRITSVKNTKKITMAMKLVAAAKVRRAQDAVLATRPFSETLQSVFGGLIARMGGEALDLPLLTQREVSKVTLVVITGDRGLCGGYNSFMIKKAEARFNELKDQGVACDMVLIGKKGITYFQRRGYPIRKTFETGQNPDSKQALAISEELLNTYLSGESDAVELLYTKFISLIASSPSARTLIPFSASEITQQGDEVFQLTSSGGDFEVERTELEVAEPQDFPNDMIFEQDPIQIINSILPLYLNGQILRTLQESVASELAARMQSMQSASDNAGDLAKRLSTEYNRARQAAVTQEILEIVSGASALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, chloroplastic, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: PFKA_BACAH
Sequence: MKRIGVLTSGGDSPGMNAAIRAVVRKAIFHDIEVYGIYHGYAGLISGHIEKLELGSVGDIIHRGGTKLYTARCPEFKDPEVRLKGIEQLKKHGIEGLVVIGGDGSYQGAKKLTEQGFPCVGVPGTIDNDIPGTDFTIGFDTALNTVIDAIDKIRDTATSHERTYVIEVMGRHAGDIALWAGLADGAETILIPEEEYDMEDVIARLKRGSERGKKHSIIVVAEGVGSAIDIGKHIEEATNFDTRVTVLGHVQRGGSPSAQDRVLASRLGARAVELLIAGKGGRCVGIQDNKLVDHDIIEALAQKHTIDKDMYQLSKELSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C10_DANRE
Sequence: MASAPAQQPTLTVEQARVVLSEVIQAFSVPENAARMEEARESACNDMGKMLQLVLPVATQIQQEVIKAYGFNNEGEGVLKFARLVKMYETQDPEIAAMSVKLKSLLLPPLSTPPIGSGIPTS
What are the official names of this protein?
Protein C10.
What is the protein family that this protein belongs to?
Belongs to the UPF0456 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y398_THEMA
Sequence: MSYDLPRLTPDKDFKVPSACGVSGIMNTSGKRFSGSVIVESMALMRERGNGLGAGYAAYGIYPELKDLYCFHMLYDSDLDKKNAEEYIKDHYEIIESEPIPTRKNPHIKEVHILWRYFLKPKFIPEDMSEEDFVVSTVMFINEKINGAFVMSSGKNMGVFKGVGFPEDIADFYRIDEYKGYIWTAHNRFPTNTVGWWGGAHPFGILDWTVVHNGEISSYGINRRFLEAYGYKCTLMTDTEVVAYLVDLFMRRFGYSPQLTAKILAAPLWKDIDLMPEEERKLYTALRMNYGGALLNGPFAIIVANNNMMMGLNDRIKLRPLVAATKDDFLYIASEESAIRVVCPEPDEVWAPKAGDPVVGVLKSARKTQVVLEGENG
What are the official names of this protein?
Uncharacterized protein TM_0398.
Protein: CARB_BACC3
Sequence: MPKRLDINTILVIGSGPIVIGQAAEFDYSGTQACQSLKEEGYKVILVNSNPATIMTDTATADKVYIEPLTLEFVSRIIRKERPDAILPTLGGQTGLNMAVELAKSGVLEECGVEILGTKLSAIEQAEDRDLFRTLMQELNEPTPPSEIIHNLDEAYGFVNEIGYPVIVRPAFTLGGTGGGICHNEEELIEIVTSGLKHSPVTQCLLEKSIAGCKEIEYEVMRDSNDNAIVVCNMENIDPVGVHTGDSIVVAPSQTLSDREYQMLRNTSLRIIRALGIEGGCNVQLALDPYSFQYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEIVNPVTQKTYACFEPALDYVVSKIPRWPFDKFESANRTLGTQMKATGEVMSIGRNLEESLLKAVRSLELGIYHLELDHLKELDKETMKKRIIKADDERLFIVAEAIRQGVTKEEINEWCEMDFFFLQKVENIVNMEREVKANVGNMEVLQTAKEMGFSDHYIAAAWNKTEREIYDMRKGNNMTPVFKMVDTCAAEFESATPYYYSTYADENESIVTDRKSVVVLGSGPIRIGQGVEFDYATVHSVWAIKEAGYEAIIINNNPETVSTDFSISDKLYFEPLTIEDVMHIIDLEKPEGVIVQFGGQTAINLAAKLEEHGVKILGTSLEDLDRAEDRDKFEAALTKLGIPQPVGKTATTVEQAVAIAEEIGYPVLVRPSYVLGGRAMEIVYRQEELLHYMKNAVKVHADHPVLIDRYMVGKEIEVDAISDGENVFIPGIMEHIERAGVHSGDSIGVYPPQSLSEKLKEQIIEHTIALGKGLNIVGLLNIQFVVFKDQVYVIEVNPRASRTVPFLSKITGVPMANVATKVILGQDLVEQGYGTGYHPEEKEVYVKAPVFSFAKLRSVDTTLGPEMKSTGEVMGKDLTLEKALYKGLVASGINIPTHGSVIITVADKDKEEAMEIAKRFHEIGYNLLATAGTAQSLAEQNIPVQVVNKIDSEDYNLLDIIRQGKAQFVINTLTKGKQPARDGFRIRRESVENGVACLTSLDTTRAILRVLESMTFSAHSMKEITQTKRHEVVHA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.