PharMolix/UniProtQA huggingface dataset:
Protein: ALD1_STAS1
Sequence: MRNFTKQYINGEWVESTSGETLEVINPATEEVAGTIAKGNKEDVEKAVEAADNVYLEFRHTSVKERQDLLDQIVQEYKNRKEDLIQAITDELGAPLSVAENVHYQMGLDHFEAARDALNDFQFEERRGDDLVVKEAIGVSGLITPWNFPTNQTSLKLAAAFAAGSPVVFKPSEETPFAAIILAEIFDKVGVPKGVFNLVNGDGQGVGNPLSEHPKVRMMSFTGSGPTGSSIMKKAAEDFKKVSLELGGKSPYIILDDADIDGAASAAANKVVFNTGQVCTAGTRTIVPASIKEDFLTAVKEKFSQVKVGNPREEGTQVGPIISKKQFDQVQAYIDKGIEEGAELLYGGPGKPEGLDKGYFARPTIFNNVDNSMTIAQEEIFGPVMSVITYNDLDEAIKIANDTKYGLAGYVYGSDKDTLHKVARSIEAGTVEINEAGRKPDLPFGGYKQSGLGREWGDYGIEEFLEVKSIAGYYN
What are the official names of this protein?
Putative aldehyde dehydrogenase SSP0762.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: SNTA1_RABIT
Sequence: MASGRRAPRTGLLELRAGTGAGAGGERWQRVLVSLAEDALTVSPADGEPGPEPGAVREPEPAQINGAAEPGAAPPQLPEALLLQRRRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAADQTEALFVGDAILSVNGEDLSSATHDEAVQALKKTGKEVVLEVKYMKEVSPYFKNSAGGTSVGWDSPPASPLQRQPSSPGPQTRNLSEAKHVPLKMAYVSRRCTPSDPEHRYLEICSADGQDTIFLRAKDEASARSWAGAIQAQINALLPWVKDELQALLAASSPAGSQDIKQIGWLTEQLPSGGTAPTLALLTEKELLLYGGLPQTREALSRPARTAPLIATRLVHSGPSKGSVPYDAELSFALRTGTRHGVDTHLFSVESPQELAAWTRQLVDGCHRAAEGVQEVSTACTWNGRPCNLSVHIDKGFTLWAAEPGAARAVLLRQPFEKLQMSSDDGASLLFLDFGGAEGEIQLDLHSCPKTMVFIIHSFLSAKVTRLGLLA
What is the function of this protein?
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins.  May link various receptors to the actin cytoskeleton and the extracellular matrix via dystrophin glycoprotein complex.  Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse.  Binds to phosphatidylinositol 4,5-bisphosphate (By similarity).
What are the official names of this protein?
Alpha-1-syntrophin, 59 kDa dystrophin-associated protein A1 acidic component 1, 59-1 DAP, Syntrophin-1.
What is the protein family that this protein belongs to?
Belongs to the syntrophin family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell junction. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions.
Protein: PSMG2_DANRE
Sequence: MFISSGDAVPSFKGFTLILPAVSVGNVGQLAVDLLISTLNMPRVGYFHTDCLIPMAGNNPYASSTEDAAQLSTSAEVYSHRDLKLAVLQIRAPIIQTKVKSFRKLMISWMKSSGFLRTVLLSSAHAYQRDDQQLHGTPLRYMLSPSLEKEERQRFEELGWREMEKISVFPGISDSEQRLYIPGGGVTKCLYTDCCTEDVPMAVVLIFCSEGDNIPDAFALINCLNDWLHLLEKPTQGSVQWRVPPSWKLLFGSGIPPLLF
What is the function of this protein?
Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg1.
What are the official names of this protein?
Proteasome assembly chaperone 2, Tumor necrosis factor superfamily member 5-induced protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the PSMG2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YHDY_ECOLI
Sequence: MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAAWAVIYPLIVWWLMYGGFFALERVETRQWGGLTLTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQYLEKRFNTGRTPH
What is the function of this protein?
Probably part of the binding-protein-dependent transport system YdhWXYZ for an amino acid; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Inner membrane amino-acid ABC transporter permease protein YhdY.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHED_METM5
Sequence: MVLKVKMGDIGVGKSPESIETLLGSCVAIILYDKGKKIGGLAHVMLPKSRMQKEKNPGKYVDTAIPELITKIVKMGARKDRLTVKLAGGAAMFGNNSNNIDVGKKNIEASKIEIKKIGLRVSSEDLGGDTGRTITLSLKDGSVMVRKGSELKTI
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: ALT_BPT2
Sequence: MMELITELFDEDTTLPITNLNPKKKIPQIFSVHVDDAIEQPGFRLCTYTSGGDTNRDLKMGDKMMHIVPFTLTAKGSIAKLKGLGPSPINYINSVFTVAMQTMRQYKIDACMLRILKSKTAGQARQIQVIADRLIRSRSGGRYVLLKELWDYDKKYAYILIHRKNVSLEDIPGVPEISTELFTKVESKVGDVYINKDTGAQVTKNEAIAASIAQENDKRTDQAVIVKVKISRRAIAQSQSLESSRFESELFQKYESTAANFNKPATAPLIPEAEEMKIGINSLASKTKAAKIIAEGTANELHYDYKFFSKSEVDEVSEKIKDVIFNAIKNEPTTSIKCLEKYAAAVNQFFEEYKDNWLDKHNKTRKGQPDEVWGEITKNAWNAAKTKFLKRMIYSFSGIGAGPMIDITIACDGSKYTPSQKRGIREYCGSGYTDINNLLLGRYNPERYDVMSEKEIESAINNLDSAFENGDRIPEGITVYRAQSMTAPIYEALVKNKVFYFRNFVSTSLTPIIFGRFGITHAGIGLLEPEARNELTVDKNEEGITINPNEIRAYKENPEYVKVQIGWAIDGAHKVNVVYPGSLGIATEAEVILPRGLMVKVNKITDASNNDGTTSNNTKLIQAEVMTTEELTESVIYDGDRLMETGEVVAMTGDIEIEDRVDFASFVSSNVKQKVESSLGIIASCIDITNMPYKFVQG
What is the function of this protein?
ADP-ribosyltransferase that efficiently ADP-ribosylates one of the two alpha subunits of host RNA polymerase RPOA on an arginine located in the C-terminal region.  ADP-ribosylation of RPOA alpha subunit enhances the transcription of viral early genes.  Also ribosylates RPOA subunits beta, beta' and sigma 70 and performs an autoribosylation reaction.
What are the official names of this protein?
NAD(+)--arginine ADP-ribosyltransferase, Alt protein.
What is the protein family that this protein belongs to?
Belongs to the Tevenvirinae NAD(+)--arginine ADP-ribosyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=About 25-50 copies per virion. This protein is injected into the bacterial cell along with the viral DNA.
Protein: Y8602_DICDI
Sequence: MKIIVLVLLILGCSQLINSQEVPSDSILFQQFINWMDNYGIFYTSGDMQSKFKSWKSNVLEIASLNSNLNVPDVLYTVTETPVSNLRTLLDAEPTIVESYPGQDIQQFEVNQFSDLTASEFSNIYAGADASLAISEVAASTLSTGAIVGIAVGGSVALIGATAATVLIVKKKRQNKKPQVSEPIATTQDVKMKPTNGIDLLNRTENQHRSITARAFYS
What are the official names of this protein?
Uncharacterized protein DDB_G0286021.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: KUP_LACDA
Sequence: MTAAGLLIAIGIVYGDIGTSPLYVMKSVIAGNGGINTVGRDLIIGTISLILWTVTLLTTVQTVIIALRATNHGEGGIFALYALIRKKAAWLVWPALIGGAAILADGTLTPAVTVTTAIEGLKGLEFGKGNVPVSNQTTVLVITIVILLVLFSIQRMGTRIIGKAFGPIMLVWFAFLGVMGLINIGGNWWILQALNPYYAIKLLFSPYNKAGFAILGSIFLATTGAEALYSDVGHVGKGNIIGSWPFVFVCLSLNYFGQGVWILNNTNMHSATEINPFYAMIPENIRLASIVLATLAAIIASQALITGSFTLVAESINLKFLPRMNILYPSDERGQIYIPAVNKMLGITTIALVLFFRTSAHMEAAYGLSITISMLTTTILLYEWLVLKQGHNLANLLFVIFFSTINILFMGSSLSKFTHGGYVSLLITLLIASVMVVWYFGNKVRDQNGAGNAYVRLDEYTDMLTNLSHDDNYPTYSDNLVYMANVKYNKFIKREILYSILDKRPKRARAYWFVTVNVTNEPFTAEYAVNTFGTKNVINIQLYLGFKKQTSVNVYLRQIVHDLIKDNTIEAQPQEYTTTPGRDVGDFKFVIVNDVISPSTTLSSYKKWLVKARVQLQNLSLNPAQWFGLEFADMVIERVPLILGKQEHERIKRVAPVDYSKTSLNKK
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SBT1_SOYBN
Sequence: MGSSIFCLHLILSSFFLFTFLLAAVNGSKKCYIVYMGAHSHGPSPTSADLELATDSHYDLLGSIFGSREKAKEAIIYSYNRHINGFAALLEEEEAADIAKNPNVVSVFLSKEHKLHTTRSWEFLGLHRRGQNSAWQKGRFGENTIIGNIDTGVWPESQSFSDKGYGTVPSKWRGGLCQINKLPGSMKNTCNRKLIGARYYNKAFEAHNGQLDPLLHTARDFVGHGTHTLSTAGGNFVPGARVFAVGNGTAKGGSPRARVAAYKVCWSLTDPASCYGADVLAAIDQAIDDGVDVINVSFGVSYVVTAEGIFTDEISIGAFHAISKNILLVASAGNDGPTPGTVANVAPWVFTIAASTLDRDFSSNLTINNQLIEGASLFVNLPPNQAFSLILSTDAKLANATFRDAQLCRRGTLDRTKVNGKIVLCTREGKIKSVAEGLEALTAGARGMILNNQMQNGKTLSAEPHVFSTVNTPPRRAKSRPHGVKTTAIGDEDDPLKTGDTIKMSRARTLFGRKPAPVMASFSSRGPNKIQPSILKPDVTAPGVNILAAYSEFASASSLLVDNRRGFKFNVLQGTSMSCPHASGIAGLLKTRHPSWSPAAIKSAIMTTATTLDNTNRPIQDAFDKTLADAFAYGSGHVRPDLAIEPGLVYDLSLTDYLNFLCASGYDQQLISALNFNRTFICSGSHSVNDLNYPSITLPNLRLKPVTIARTVTNVGPPSTYTVSTRSPNGYSIAVVPPSLTFTKIGERKTFKVIVQASSAATRRKYEFGDLRWTDGKHIVRSPITVKRR
What is the function of this protein?
Produces a rapid alkalinization of the cellular media and the induction of defense-related genes, including chitinase 1b, chalcone synthase and CYP93A1.  The receptor for GmSubPep is probably different from the receptor(s) for GmPep890 and GmPep914.
What are the official names of this protein?
Subtilisin-like protease Glyma18g48580.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL25_RUTMC
Sequence: MSLTINALTRDDQGKGASHRLRRNHKIPAIVYGTGKAPRNITLDVFEITRLLENEESYTSVLDLIVDKKKEAVIIKDLQRHPAKNIVTHVDFLRINLKQAIVTSVPLHFNGEENNEAMRLGAILNQFVTSVEVSCLPTDLPHAIDVDISNLTMGEHISFTGLNIPKGVVITALTHGDIETHNRSVVAIQEPRKIAEIEEETSIIVEDENIESNNADKNKSNS
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PYRC_STAAM
Sequence: MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIIDAKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEHFEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMMYEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLLAEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMNPPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLYTHFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFLSKADNTPFIGYKVYGNPILTMVEGEVKFEGDK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: RNAS1_ORYLE
Sequence: ASTSNYCNQMMKSRNLTQNRCKPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPN
What is the function of this protein?
Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides.  Acts on single-stranded and double-stranded RNA (By similarity).
What are the official names of this protein?
Ribonuclease pancreatic, RNase 1, RNase A.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: BCEA_HALH5
Sequence: MAILEATNIHKSYGTKLNKQEVLKGIDIRVEKGEFVSIMGASGSGKTTLLNVLSSIDKLSNGSIKIEGSEMTRLKEKELAQFRKKHLGFIFQEYNLLDTLTVKENILLPLSITKIPRKAADEKFKQVATELGIYEIKDKYPNEISGGQKQRASAARAFIHEPSIIFADEPTGALDSKSASDLLGKLQQLNEKLRATIVMVTHDPVAASYCSRVIFIKDGQIYTQLHKGDESRQTFFKDIMKTQGVLGGVQNDH
What is the function of this protein?
Part of the ABC transporter complex BceAB (TC 3. A. 1. 123. 5) involved in bacitracin export.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Bacitracin export ATP-binding protein BceA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: IWS1_ASHGO
Sequence: MSGSSSVHSGTAASEEWGMPSVGEIGAAGEAVETNEVERAQHQERQRKHIATSDNDEEESGNKWSVSTLPITSYGGDGDAAGGSGRRQALEAKMERLLKKPKARHSRQDEEDLEQYLDEKILRLKDEMNMAAQKDIETLNRRLETGDNRLIAMEKVTLLPKVISVLNKANLADTILDNNLLQSVRIWLEPLPDGSLPSFEIQKSLFAAIENLPIKTEHLKESGLGKVVIFYTKSKRVEHKLARLADRLVAEWTRPIIGASDNYRDKRVLKMDFDVEKHRKKAALDSAKSKKRRKAAVDEEKHKSLYELAAAKRNRAAAPAQTTTDYKYAPVSNISNVQTGIRTAGVGSTLNNNDLYKRLNSRLAKSKRSK
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor IWS1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPMI_ALKCK
Sequence: MSKKPVALIILDGFGLREEEKGNAVAHAQKPNFDRYWNEFPHATLRADGENVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNLSIREGDFFKNETFIKAMDHVKEKQSALHIYGLLSDGGIHSHIDHIYALLDMAKQQNVERVYVHGFLDGRDVGPTSAEVYLKGLQDKFDEVGLGKLATVHGRYYAMDRDKRWDRVEKSYRAMVYGEGPSYKNGLELLDDSYKNNIVDEFVIPSVITEEDGTPVATVKDDDAVIFCNFRPDRAIQLSQVFTNEDFRGFDRGEKMPKRLHFVCLTKFSETVKGFVAFKPTNLDNTLGEVLSQQNYTQLRIAETEKYPHVTFFFSGGREDEFPGEERILINSPKVATYDLKPEMSAYEVTDALVKEIEGEKHDVIILNFANPDMVGHSGMLEPTVKAIEAVDECLGRVVDALLQKGGAAIITADHGNADEVVTLDGKPMTAHTTNKVPVIVTEKGITLREDGILADLAPTVLDLLGADKPKEMTGKTLKQ
What is the function of this protein?
Essential for rapid growth and for sporulation.  Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: Y097_PORGI
Sequence: MGRAFEYRKARKMKRWGNMARVFTKLGKEITIAAKEGGPDVETNPRLRILVQTAKKENMPKENVERAIKKATSKDYTDYKEMNYEGYGPYGIAIFVETATDNTTRTVANVRSYFNKHGGSLGTSGSLEFLFQHKCVFHIVKKDDMDLESLELELIDYGVDELEEDENEIILYGDFSENSNIQKYLEDAGYEIASAEFVRIPNDTKEVTAEQREQIEKLIERIEEDEDVQNVFHNMKEEEGEE
What are the official names of this protein?
Probable transcriptional regulatory protein PG_0097.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_MYCTU
Sequence: MAELAPDTVPLAGVVLAGGESRRMGRDKATLPLPGGTTTLVEHMVGILGQRCAPVFVMAAPGQPLPTLPVPVLRDELPGLGPLPATGRGLRAAAEAGVRLAFVCAVDMPYLTVELIEDLARRAVQTDAEVVLPWDGRNHYLAAVYRTDLADRVDTLVGAGERKMSALVDASDALRIVMADSRPLTNVNSAAGLHAPMQPGR
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLM2_YEAST
Sequence: MSYQRNSARASLDLRSQYQQLEGRMRSEHFNPAYQQQQQKGQNIPLSLPSSLAQRNPIPYPIDAVTSDPTIPAQLNVYDHDRQNSIVDAAAGTNTTHSLNSNNIPSSQNNNINNNNINNVGSFTDPSMLTLPKMSLHSHQKQYDSNQNDPRSPLAILIPTSAQPTDVLSARFSAWRNVIRAILVYLSETASIQDEIVRQQLRLSHAVQFPFFSIENQYQPVSNEDKSMQKFFLPLGSGSVQDLPTMLTKYHDNLASLASKSSKELTSEIIPRLEDLRRDLLVKIKEIKALQSDFKNSCNKELQQTKHLMKLFNESLKECKLGTPKSDPFLIKLQLEKQIKRQLVEENYLHEAFDNLQNSGAQLESVIVMEIQNGLTSYARILGKEAQVVFDSVISKLDSTILNKNTNLEWDSFILRNISNFVPPNLPMRRFKEISYSNQNDPFTFEVKSGFLEKRSKFLKSYSRGFYVLTPSFLHEFKTPDKHKFSTPLMSIPLVECTVTEHSKKTKSNSEQGKNKFILRTNSNGLIHRGHNWVFKVDSYDDMIEWFGNIKALSSLPNYDDKCKYVSKVAKLSKEKAKSNENTTESVTPQVTNEQHTRYDDVSSSNFPLNSIPKLDNLTITNTTSSIPETNDSQIQNRVPEFYIENVDSPRKSNQL
What is the function of this protein?
Together with SLM1, effector of the TORC2- and calcineurin-signaling pathways.  Phosphorylated and activated by TORC2 under favorable growth conditions.  Mediates actin polarization via inhibition of calcineurin-dependent transcription.  Upon nutrient limitation or environmental stress, gets dephosphorylated by calcineurin, inhibiting interaction with TORC2, thereby antagonizing TORC2 signaling and mediating calcineurin-dependent actin depolarization.  Also functions in heat-induced, calcineurin-mediated uracil permease (FUR4) endocytosis.
What are the official names of this protein?
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM2, Synthetic lethal with MSS4 protein 2, TORC2 effector protein SLM2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LANNA_STAHO
Sequence: MENSKIMKDIEVANLLEEVQEDELNEVLGAKKKSGVIPTVSHDCHMNTFQFMFTCCS
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic nukacin, Nukacin KQ-1, Nukacin KQU-131.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
What are the subcellular locations of this protein?
Secreted. Note=Through the specific ABC transporter nukT.
Protein: PDXT_METM5
Sequence: MKIMGILGIQGDIEEHEDAVRKINCIPKRIRTVDDLEGIDALIIPGGESTTIGKLMVSYGFIDKIRNLKIPILGTCAGMVLLSKGTGKEQPLLDILNVTIKRNAYGSQKDSFEKEIVLGGKEIHAVFIRAPQVGDILSKDVEIISKDDENIVGVKQGNIMAISFHPELSDDGVIAYEYFLKNFVEKN
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: DAPA_STAHJ
Sequence: MPHLFEGVGVALATPFTNNEVDYNALEKHVDFLLDNGVKAIIVNGTTAESPTLTEEEKEQVLESVIKQVNHRVTIIAGTGTNNTAKSIQASQRAKALGADAIMLITPYYNKTNQRGLVKHFETIANEVELPVVLYNVPSRTNMTIEPETVETLSHNQYIVAIKDATNDFEYYEDVKSRINQEEFALYSGNDDNVVEFYQRGGNGVISVIANAIPKEFQALYDAKQSGQDISNDFEPISKLLDALSVDVNPIPIKALTSHLGFGNYELRLPLLPLEDADAKVLINVFEQFKAGEL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPZ_CAEEL
Sequence: MADFDTNPTSLYSIKGIVILDQDGNRVLAKYYDRTTFGTVKEQKAFEKSLFSKTSRNTSADILLLDGVTCLYRSNVDLYFYVLGSTRENELFLDATLTCLYDAVSVVLRKNVEKKALIDSMDTIMLIIDEICDEGIIMETDAQAVVQRTALKSDEVSFSDQSVSQIGFSFMKSANEQFKWSLLK
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Probable coatomer subunit zeta, Zeta-coat protein, Zeta-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: PUR9_MYXXD
Sequence: MLALLSVSDKRGLVPFAQGLVRLGFRLLSTGGTLEALKGAGVPVNKVSEHTQSPEILGGRVKTLHPRIHGGILGRLELEADREEMKAHGIEPISLVAVNLYPFRQTVASGAAEPEVIEQIDIGGPAMVRASAKNFRHVSVVVDPDDYPAVLAELEQQKAVSEDTRRRLMRKAFAHTAAYDASISAWLSAQAGEPFPGELSLAFQKSQDLRYGENPHQRGAFYREHAAPQEPTVAFAKVLQGKELSYNNILDLDAALGLLLEFPEAPAAVIIKHNTPCGVAVDAALVKAYRTARAVDEVSAFGGIVALNREVDAATAQAMAETFLEAVIAPSYSPEALQVLATKKNLRLLEAGPALASPQARPRAQLDARSVSGGMLLMDRDSVEPPLSWKVVSKRAPTPEEEQAMRFAWKVCKHVKSNAIVFASGDQLLAQGGGQTNRVDSVRIAMQRGGAALRGSAVASDAFFPFRDGLDEAARAGATCVVQPGGSVRDAELIAAADEHGMAMVLTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: CRERF_MOUSE
Sequence: MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYELDREMNYQQNPRDNFLSLEDCKDIENLETFTDVLDNEDALTSNWEQWDTYCEDLTKYTKLTSCDIWGTKEVDYLGLDDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSLFSVKQNPLPPSSFPSKKITNRAAAPVCSSKTLQAEVPSSDCVQKASKPTSSTQIMVKTNMYHNEKVNFHVECKDYVKKAKVKINPVQQGRPLLSQVHIDAAKENTCYCGAVAKRQERRGVEPHQGRGTPALPFKETQELLLSPLTQDSPGLVATAESGSLSASTSVSDSSQKKEEHNYSLFVSDNMREQPTKYSPEDDEDDEDEFDDEDHDEGFGSEHELSENEEEEEEEEDYEDDRDDDISDTFSEPGYENDSVEDLKEMTSISSRKRGKRRYFWEYSEQLTPSQQERILRPSEWNRDTLPSNMYQKNGLHHGKYAVKKSRRTDVEDLTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRLKKKAQYEANKVKLWGLNTEYDNLLFVINSIKQDIVNRVQNPREEREPSMGQKLEILIKDTLGLPVAGQTSEFVNQVLGKTAEGNPTGGLVGLRIPASKV
What is the function of this protein?
Acts as a negative regulator of the endoplasmic reticulum stress response or unfolded protein response (UPR).  Represses the transcriptional activity of CREB3 during the UPR.  Recruits CREB3 into nuclear foci (By similarity).
What are the official names of this protein?
CREB3 regulatory factor, Luman recruitment factor, LRF.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. CREBRF subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with CREB3 in nuclear foci.
Protein: DHSO_PIG
Sequence: MAAAKPENLSLVVHGPGDLRLENYPIPEPGPNXVLLKMHSVGICGSDVHYWQHGRIGNFVVKKPMVLGHEASGTXVKVGSLVTHLKPGDRXAXEPGA
What is the function of this protein?
Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols.  Is active with xylitol, L-iditol and D-sorbitol (D-glucitol) as substrates, leading to the C2-oxidized products D-xylulose, L-sorbose and D-fructose, respectively (By similarity).  Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism.  May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By similarity).
What are the official names of this protein?
Sorbitol dehydrogenase, SDH, L-iditol 2-dehydrogenase, Polyol dehydrogenase, Xylitol dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein. Cell projection, cilium, flagellum. Note=Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
Protein: RL26B_CANAL
Sequence: MAKISQDVSSSRSKARKAYFTASSVERRVLLSAPLSKELRQQYNVKSLPIRQNDEVLVVRGSKKGSEGKVNSVYRLKFAIQVDKLQKEKSNGASVPINIHPSKVVITKLHLDKDRKALIQRKGGKAE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L26-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.