PharMolix/UniProtQA huggingface dataset:
Protein: DCUP_THEFY
Sequence: MILGHAARSLREHGTIRSVTLQDSAFLRACRRQPVPHTPVWFMRQAGRSLPEYRKLREGVPMLEACARPDMIVEITLQPVRRYNVDAAIFFSDIMVPLKAIGVDLDIKPGVGPVVAEPIRDLAATRRLRGLEPDDVPYVTEAIRELVRELGSRPLIGFAGGPFTLASYLIEGGPSRHHEHTKALMYGAPEVWTELMRRLSAITLEFLRVQIAAGASAVQLFDSWVGALSAEDYRANVLPYSSWIFAQLAEFDVPRIHFGVGTGELLGLLSEAGADVVGVDWRVPLDQAARRVRPHTALQGNLDPAVLFAPWSVVAERTDDVLARAKAAEGHVFNLGHGVLPTTDPAVLERLVEYVHTQTAN
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_PELUB
Sequence: MRVFIDKLKDKQDLSFAESKNAFEILMNGKASDDEIFDFLTLLSSKGESSDEIAGGVFVLRDKSKRVNVDDCIDTCGTGGDGMNTLNISTASALLLSSMGIKVAKHGNKAVSSKCGSGDVLEALNIKIDLEPKDIEEQIKKNNFGFMFAPNYHSAMRFVGPTRKKIGKRTIFNMIGPLSSPALVDRQVIGVFDKKLLKIFANALNNLDIKFAWIVNSEDGLDEISPYSKTNVVQLKDGKISEMLIDPIKLNIGANKFENLLGDDAKFNANKMLDIFKGEDNDFSKAVCLNAAAGLIVSEKYTIFIDAYNEARTHILSGKTYNDLKEIQNV
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: REPLM_BACIU
Sequence: MKERYGTVYKGSQRLIDEESGEVIEVDKLYRKQTSGNFVKAYIVQLISMLDMIGGKKLKIVNYILDNVHLSNNTMIATTREIAKATGTSLQTVITTLKILEEGNIIKRKTGVLMLNPELLMRGDDQKQKYLLLEFGNFEQEANEID
What are the official names of this protein?
Replication and maintenance protein, Plasmid replication protein.
Protein: GERPB_BACCR
Sequence: MNFYVNQSIIINSIKIDSITTSSVFQIGTAGSIKALSKFSNTGGFTEPLRPLQAKGQIISIKPSTSSS
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor (By similarity).
What are the official names of this protein?
Probable spore germination protein GerPB.
Protein: PANC_CROS8
Sequence: MLIIETVPLLRQQIRRLRMEGKRIALVPTMGNLHDGHMKLVDEAKASADAVVVSIFVNPMQFDRADDLARYPRTLQEDCEKLKKRGADFVFAPTPEEVYPQGMSDQTYVDVPGLSTMLEGASRPGHFRGVSTVVSKLFNLVQPDVACFGEKDYQQLALIRKMTADMGYDIEIIGVPTVRAKDGLALSSRNGYLTSDQRKIAPGLSKVMNTMAEKLRAGERDLEAIIAAASEALSEKGFRPDDLQIRDADTLQALSPASQRAVILMAAWLGQARLIDNQTVELTQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_ZYMMO
Sequence: MALSDPLGDLLTRIRNGQHARKDSVVSPASKLRVRVLDVLAREGYIRGYTEAKLGNHDALRIELKYFEGQPAIHHLARVSKPGRRIYSGSRELPRVRNGLGITIVSTPKGVLSDAEARDQNVGGEVLAEVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SYC_SALCH
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHQDFDALNILRPDSEPRATHHIQEIIELTRTLIEKGHAYVADNGDVMFDVPTDPTYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKMSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGEYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARASLERLYTALRGTDKSAAPAGGEAFEARFVEAMNDDFNTPEAYSVLFDMAREVNRLKGEDMTAANAMASHLRKISGVLGLLEQEPDVFLQSGAQADDGEVAEIEALIQQRLDARKAKDWAAADAARDRLAEMGIILEDGPQGTTWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTI_CERNC
Sequence: MPSTSKRPTAIVIGSGVGGVSTAARLARAGFHVTVLEKNNFTGGRCSLIHHEGYRFDQGPSLLLLPGLFHRTFAELGTSLEQEGVKLLKCEPNYMIHFSDGEKFTLSSDLSVMKTEVEKWEGKEGYTRYLEFLKESHGHYELSVREVLLRNFEGLTAMLRPEFLRHLLQLHPFESIWTRAGKYFWTERLRRVFTFGSMYMGMSPFDAPGTYSLLQYTELAEGIWYPVGGFHRVVEALVKIGEREGVDFRMETAVKKILLSEDGGVAKGVELEDGRRLEADVVVNNSDLVYAYEKLLPIKTPYAESLKGRPGSCSSISFYWALDRQVPELEAHNIFLADEYRESFDSIFKKHLIPDEPSFYVNVPSRVDSTAAPEGKDSVVVLVPVGHLLEEDRHASQAHQLSASRNGHISSASPPDQPGLTPTEKQDWPAMISLARKTILSTIQSRTNVDLTPLIIHESTNSPLSWKQTFNLDRGAILGLSHSFFNVLCFRPTTRARKPGAFDAQLLKFGVLGRAAEVIIDAFRGRGKDIKGLYMVGASAHPGTGVPICLAGGALVAEQICGDYGVDIPWKEEERKGRDVGGKRKLDVLESPMWLDSWEQWVSVLIYLLVGIFAWLWMKFR
What is the function of this protein?
Phytoene desaturase involved in the carotenoid biosynthesis pathway.  Converts phytoene into 3,4-didehydrolycopene via the intermediary of phytofluene, zeta-carotene, neurosporene and lycopene, by introducing up to five double bonds into phytoene (By similarity).
What are the official names of this protein?
Phytoene desaturase, Phytoene desaturase (3,4-didehydrolycopene-forming).
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TRPB_TRIEI
Sequence: MTITPLNPTSTQQPDSLGRFGKFGGKYVPETLMPALLQLETACKKYSQDPTFKQELQQLLRDYVGRPSPLYFAERLTAHYTKPDGTGPQIYLKREDLNHTGAHKINNALGQALLAQRMGKQRIIAETGAGQHGVATATVCARFGLKCVIYMGIHDMERQALNVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGVETRAQCLEKWNGLPDILMACVGGGSNAMGLFHEFINDPSVRMIGVEAAGKGVDTNKHAATLTLGRVGVLHGAMSYLLQDEEGQIIEPHSISAGLDYPGVGPEHSFLKDSGRVEYYSVTDNEAVAAFQRLSQLEGIIPALETAHAIAYLETLCPQLSGSPRIVFNCSGRGDKDVQTVGKFLEG
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RR20_THAPS
Sequence: MANNKSAKKRILITKRNNLQNRFYKSSVRTLTKRFLSDLETYKISQSNTDKDKLQNGLSSIYSLIDKGYKKNVYHKNTAARKKSKLAALLKAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YVCQ_BACSU
Sequence: MLKTYLIDRLAIILFSLLGIGSAMLIAYLSIVESGAEPSKENMMYIWILPGTLLAAGFAADYVRQFSFLTYVKKLAEQASSSNDIGQSLKARKPRTGEQALWTKMINALGQQYESRLSQYINQQKQHYTFTNQWVHHMKTPVSVISLMIQEGKNGTSSSFPTFLEELEDENERFRHGLDMMLQTARLEEFAFDVKPQTFDLAEMVRSLINQEKRQFIKRRLFPTLHVPPNAVQISSDQKWLSFVVEQILFNALKYSKQGVGDPITIRIETQGHETRLSVADEGIGIPPQDLPRIFDAFFTGENGRTMKEATGMGLYLAKQVCSRLGHKLYAESKEGAGTVMTIVFSSDTLVNVTAL
What is the function of this protein?
Member of the two-component regulatory system YvcQ/YvcP.  Probably activates YvcP by phosphorylation.
What are the official names of this protein?
Sensor histidine kinase YvcQ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLPB_FUSNN
Sequence: MNPNQFTENTISAINLAVDISKGNMQQSIKPEALALGLLMQNNGLIPRVIEKMGLNLQYIISELEKEMNNYPKVEVKVSNENISLDQKTNSILNRAEKIMNEMEDSFLSVEHIFKAMIEEMPIFKRFGISLEKYMEVLMNIRGNRKVDNQNPEATYEVLEKYAKDLVELAREGKIDPIIGRDSEIRRAIQIISRRTKNDPILIGEPGVGKTAIVEGLAQRILNGDVPESLKNKKIFSLDMGALVAGAKYKGEFEERMKGVLKEVEESNGNIILFIDEIHTIVGAGKGEGSLDAGNMLKPMLARGELRVIGATTIDEYRKYIEKDPALERRFQTILVNEPNVDDTISILRGLKDKFETYHGVRITDTAIVEAATLSQRYISDRKLPDKAIDLIDEAAAMIRTEIDSMPEELDQLTRKALQLEIEIKALEKETDDASKERLKVIEKELAELNEEKKVLTSKWELEKEDISKIKNIKREIENVKLEMEKAEREYDLTKLSELKYGKLATLEKELQEQQNKVDKDGKENSLLKQEVTADEIADIVSRWTGIPVSKLTETKKEKMLHLEDHIKERVKGQDEAIKSVADTMLRSVAGLKDPNRPMGSFIFLGPTGVGKTYLAKTLAYNLFDSEDNVVRIDMSEYMDKFSVTRLIGAPPGYVGYEEGGQLTEAIRTKPYSVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRIVDFKNTLIIMTSNIGSHFILEDPNLSEDTREKVADELKARFKPEFLNRIDEIITFKALDLPAIKEIVKLSLKDLENKLKPKHITLEFSDKMVDYLANNAYDPHYGARPLRRYIQREIETSLAKKILANEVHEKSNVLIDLDNNHIVFKEV
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_STAAR
Sequence: MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVGYTVDSHKFCQSVADQGCKLVVVNKEQSLSANVTQVVVPDTLRVASILAHTLFDYPSHQLVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLTKKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHAKSLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVTPYEVFSYGIDEEAQFMAENIQESLQGVSFDFVTPFGTYQVKSPYVGKFNISNIMAAMIAVWSKGTSLETIIKAVENLEPVEGRLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQPFVKQKLIFLVGMAGERDLTKTPEMGRVACRADYVIFTPDNPANDDPKMLTAELAKGATHQNYIEFDDRAEGIKHAIDIAEPGDTVVLASKGREPYQIMPGHIKVPHRDDLIGLEAAYKKFGGGPVGQ
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB1_SACD2
Sequence: MAYKVLVVDDSQFFQVRLKQIINEHPDLEVVGIAANGQEAIDLEESLRPDIISMDYEMPHLDGISAVRSILSKRPIPIVMFSSMTYEGATITLEALDAGAVDFIPKNFAEVSRDSVVLKKRLHEKLLLFAQKAKPSVAARSTTQPSGVRPSALGANLSSSRSPRPASSAPSAPKKRIKGLVKLVAIGASTGGPVAVSEIITRLPANFPVPVIVAQHMPENFTKAFSERLNRQSAVEVREAQDGDLLKSGVVYVAPGGNQLMVDKTGRSIRILDGDARLTYKPSVDVLFASAASAMGDKVLAIVLTGMGADGCDGAKLLKQKGATIWGQDKDSCVVYGMPAAVAKAGLTDEVLPLDQVWQRLVSDV
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H18C1_CYRHA
Sequence: MKLSIIIIATSLVIAVVAFPSKDSKAIENDKTEQRMEIVVQETARACSKQIGDKCKRNCECCRKTVVCGTIYVGGKEVNQCMDKTSDNAILNGLGKGMNFIENTFSFCV
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XVIII-3, HNTX-XVIII-3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. F7 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RSSA_PARBP
Sequence: MAPSNLPPVFNATSQDIEMLLAAQCHLGSKNLQVHMEPYLWKTRPDGINVINIGKTWEKIVLAARIIAAIDNPADICVISARPYGQRAVLKFAAHTGAVAIAGRFTPGNFTNYITRSFKEPRLIIVTDPRTDSQAIKEASYVNIPVIALCDTDSPTEFVDVAIPTNNKGRHAIGLIWWMLAREVLRLRGTLANRESEWDVVVDLYFYRDPEAEENKEIEETKVPGAEEVGAAAIESGLVGDSWQAQATPGFSAGVAVPGTAVPGWEADVSTDWAASSAPAAETLADPAADPSVKW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJL2B_YEAST
Sequence: MKMFLFLNESYIFDRLRMWSIVLWHSCVFVCAECENANYRGAEVP
What are the official names of this protein?
Putative UPF0377 protein YJL222W-B.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
Protein: Y113_AQUAE
Sequence: MKKYVLPLLFLSSLSLAEEKSLYLKVSQPLELYGGISAGYFYTTNEDGKDSSDKLQITNAILGLKAEVGEKIRFGFDLAVGGSLWSTVWDGGQGDFSYYDPDEKELKEGVGLHWGYAYLKPFKGFEVSAGVLTTNIGYELADTYSNPNVTFGAVWYAQPFIYPGVRLTLDFSEIADLPVSLYAEYNQEYDLDNYAVGILGELGNLSYALSYYDYRASKNLVDLVLGYTIFNVDLGLNFDYQWLDDSAKSAGQDDSAYGVALYVIPKFETKYGEFSLPLRLEYFDEGSSGIYFGGADKGYTLTVTPTFRPTPNTYVRAEVSYVNTDNKVFKNGTKDNKTTLAVELGFTF
What are the official names of this protein?
Uncharacterized protein aq_113.
Protein: PYRE_YERPP
Sequence: MKAYQREFIEFALNKQVLKFGEFTLKSGRISPYFFNAGLFNTGLDLAKLGRFYAAALMDCGVEFDLLFGPAYKGIPIATTTAVALAEHHERDVPYCFNRKEAKTHGEGGNLVGSPLQGRVMLVDDVITAGTAIRESMEIINAQGATLAGVMISLDRQERGRGEISAIQEVERDYHCKVIAIVTLNDVIRYLEDKPEMAEHLVAVRQYREQYGVTL
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS17_MICAN
Sequence: MAVKERVGVVVSDKMDKTVVVAIENRSPHPKYGKIVVKTQKFKAHDAENQAKQGDRVRIRETRPLSKTKRWEVAEILTDS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: PGK_BORHD
Sequence: MSIKTIKDFDFSGKRALVRCDFNVPLREGNITDDTRIRAALPTIEYLKSQGARVVLMSHLGRPKGERNLKYSLMPVAKRLSELLGQDVKMLPDCIGDEVATAVSNMKNGDVVLLENIRFYRQEEENCNDFAKKLSQNGDIFVNDAFGTAHRAHASTAGLAAYLPAVGGFLMEKEDEFLGKILKNPESPFVSIIGGSKVSSKIAVLESLLPKSNVMVIGGGMAYTFLKVEGHSIGKSLLENEYIDVAASFLKKAKELDVKVILPLDHIVASEFKEDSIPEYVDAIDIPDGKIGMDIGEKTLRKIEEVLVSAKTVIWNGPLGVFEFDSFSKGTAKVAEYVASCSGITVVGGGDSVAAVNKFNLSEKITHVSTGGGASLEYLEGKILPGIKVLEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_BRADU
Sequence: MADLQKIVDDLSSLTVLEAAELAKLLEEKWGVSAAAAVAVAGPAGGGAAAAPAEEKTEFTVVLASAGEKKIEVIKEVRAITGLGLKEAKDLVEGAPKPVKEGVNKDEAEKIKVQLEKAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: NEP4_DROME
Sequence: MSRHSQLKLAMPSVHGAPATAPGSPMNAKARSVKLGLGVNQRTGRVQWCPGLTCCKMLLLLPVVMLPLTLVLILIMRLDGMLAALQLNEQRMRDLRNSHSEVPVYMEDYEALLPEGSTYNDLINEEFILPASKRTQLQILAAERARRCQPYRYGNGESMELEERNTLMKDSRTSFLPLGIPRECLGSGIELDIKPIDEEAYQRQKKRYQDIAPYWLEKIRIRERREAERHAEEASAEISEATAALQSFWNEEGTREGIRMTQAKTMKRYMDNKVDPCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLESQWSESNFNWQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGLPTREYFLQPSNAKYLQAYQRYMAEVMHKMGASKADAQRVASELVAFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVPEIKWRAYLQSLQDREVLGTEEVVIYAVEYMSKLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNTNMGMAVGSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTDWLDDTTKQLAEEKVNAMSLKIGYPDFILNPSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLHERVNKTNWQTAPAIVNAYYSRNKNQIMFPAGILQPPFYHRHFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTDSSIRGFDERARCIIAQYSNYTVEEVGIVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSEVSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQKKCSVW
What is the function of this protein?
Cleaves angiotensin-1 and tachykinin neuropeptide substance P (PubMed:19880729).  Functions in maintaining muscle integrity, possibly independently of its endopeptidase activity (PubMed:22583317).
What are the official names of this protein?
Neprilysin-4.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
[Isoform A]: Cell membrane; Single-pass type II membrane protein. Sarcoplasmic reticulum. Note=In larval muscles, localizes to both the cell surface and sarcoplasmic reticulum membranes that are continuous with the nuclear membrane. SUBCELLULAR LOCATION: [Isoform B]: Cytoplasm.
Protein: RPIA_DICNV
Sequence: MNQQLLKEKVAAAVLEHVPENITLGVGSGSTVLCFIEALKQAKRQFRDIVAASETSSKALEAAGFRVRDLNACDPPDIYVDGADEINDDKIMIKGGGAALTREKIIASAAKEFICIIDESKKVAQLGRFPVAVEVIPMARSYVAREIVKLGAEPRWRQGVVTDNGHWILDVHYLDLTAAERMEARINTIAGVVECGIFAQRRADKVLMSQSDGEIVLW
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: U21_HHV6Z
Sequence: MMICFVFLCVLTFVRGEIYPSTCPALGAGNGEAVRSGEMLLEISAYRNWRSGKMELWGSAAVNNQVFYGGMEDSQIEYDFGKFLVFRCFQVFHNVHKLLFNTVSSATMHLARKRVQKCGHGKMTFISIQVQCSVNKKSIRLSRMNETNLKKQVLRVAFFLDGSNNSWIADKNFQGEDRTMLRLWTELSTYRQYLISSCNNDVKVLSELYGEFRRMALSYDEELKLNFMPVIRSSSERLFRADDLKCSFSRWLGAEGEFAVCEYSGWGVSKLGKIEIFAEEPLTFDMVWKTVKMRSSGAYTSLFRDDVTWGLISLDKWVGDKYFCMCTNKESGDNVIVTLPEKNVEKSIQIYNEGSTMLAFAEITSIMVNLMFMGAVAVCVGILGISCFVGLKEIIYFIFVSVNSMWPFCNKLLTTAVNCFFKGRTFLRRELKI
What is the function of this protein?
Binds to MHC class I molecules in the endoplasmic reticulum and targets them from the Golgi directly to the lysosomes.  Once in the lysosomes both proteins are degraded.  In consequence, surface class I molecules are down-regulated and infected cells are masked for immune recognition by cytotoxic T lymphocytes (By similarity).
What are the official names of this protein?
U21 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae U21 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: MURD_THEM4
Sequence: MKFTLLGFGLSNKEIFKYLVKNGHEVFVSEGKKLASSDKKLLLENGVQFEENGHTEKALECDIILVSPGVHFENEIIKEAKRRSIEIDTEISFCQREFEKIGWTPFVIAVTGSVGKSTTVSLIYHLLNKKVRALLAGNIGIPIAKLLNDNLRANYLVLEISSFQLFWSKRFKPNISSILNIYPNHLNWHPDMEHYVSSKFKIASFQSKDDVFVYNPNDEYIRKNLYKVSAKKVPFRFDFSIEKLPIHLRYRQTVENVAAAKTILETMGYEFKWEFLEDFEKLPHRMEYVTEINGVKFFNDSKATNAIAVIRAIENFDDKLHLIMAGIGKNEDYTLLAKIIKEKVKILALVGPIADEIEPYLDGVRYFKVDTINQAVNQLFSMASRGDVIMLSPGGASFDAFKNFEERGEYFKQLVMQLKEGNCEEC
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_COXB2
Sequence: MATHSTNEFRGGLKVMVDGDPCSIIDNEFVKPGKGQAFNRVKFRNLKTGRVLERTFKSGETLPAADVVEVEMQYLYNDGEFWHFMTSENYEQHAASKEAVAEAKQWLKEEALCMVTMWNGVPLSVEPPNFVELKITETEPGVRGDTATGGTKRAKLETGAVVRVPLFLNEGEIIKVDTRRGEYVSRAK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PWP2A_HUMAN
Sequence: MAAVAAEAAATAASPGEGGAGEAEPEMEPIPGSEAGTDPLPVTATEASVPDGETDGQQSAPQADEPPLPPPPPPPGELARSPEAVGPELEAEEKLSVRVAESAAAAPQGGPELPPSPASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQLIPGSEVRVTLDHIIEDALVVSFRFGEKLFSGVLMDLSKRFGPHGIPVTVFPKREYKDKPEAMPLQSNTFQEGTEVKCEANGAVPDDPSPVPHPELSLAESLWTSKPPPLFHEGAPYPPPLFIRDTYNQSIPQPPPRKIKRPKRKMYREEPTSIMNAIKLRPRQVLCDKCKNSVVAEKKEIRKGSSATDSSKYEDKKRRNESVTTVNKKLKTDHKVDGKNQNESQKRNAVVKVSNIAHSRGRVVKVSAQANTSKAQLSTKKVLQSKNMDHAKAREVLKIAKEKAQKKQNETSTSKNAHSKVHFTRRYQNPSSGSLPPRVRLKPQRYRNEENDSSLKTGLEKMRSGKMAPKPQSRCTSTRSAGEAPSENQSPSKGPEEASSEVQDTNEVHVPGDQDEPQTLGKKGSKNNISVYMTLNQKKSDSSSASVCSIDSTDDLKSSNSECSSSESFDFPPGSMHAPSTSSTSSSSKEEKKLSNSLKMKVFSKNVSKCVTPDGRTICVGDIVWAKIYGFPWWPARILTITVSRKDNGLLVRQEARISWFGSPTTSFLALSQLSPFLENFQSRFNKKRKGLYRKAITEAAKAAKQLTPEVRALLTQFET
What is the function of this protein?
Chromatin-binding protein that acts as an adapter between distinct nucleosome components (H3K36me3 or H2A. Z) and chromatin-modifying complexes, contributing to the regulation of the levels of histone acetylation at actively transcribed genes (PubMed:30228260, PubMed:30327463).  Competes with CHD4 and MBD3 for interaction with MTA1 to form a NuRD subcomplex, preventing the formation of full NuRD complex (containing CHD4 and MBD3), leading to recruitment of HDACs to gene promoters resulting in turn in the deacetylation of nearby H3K27 and H2A. Z (PubMed:30228260, PubMed:30327463).  Plays a role in facilitating transcriptional elongation and repression of spurious transcription initiation through regulation of histone acetylation (By similarity).  Essential for proper mitosis progression (PubMed:28645917).
What are the official names of this protein?
PWWP domain-containing protein 2A.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRF_AZOSB
Sequence: MHFMTALRAAWQQRDSLLCVGLDPDPARFPAHLQGRPDAIFEFCAAIVDATADLVCSFKPQIAYFAARRAEDQLEALIDHIHAHHPGVPVILDAKRGDIGSTAEQYAVEAFERFKADAITVNPYMGRDSVDPYLAYPDKGVILLCRTSNPGGSDLQFLDVGGEKLYERVARLVAEDWNASGNCGLVVGATFPAEIARVRALTGEMPLLVPGIGAQGGDIEATVKAGRTAAGGGLMINSSRAILYAGKGEDFAAAARAAALQTRDAINAYR
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: SRP19_METBF
Sequence: MRDRGKLVIWPVYLDQTKSRSSGRIISRKNAIKEPQLNEIKEAARQLGLNPEVEPHKAYPKSWWEVSGRVLVDDNGPKTVIAKQIALAIKKMRGPESSAKA
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm.