PharMolix/UniProtQA huggingface dataset:
Protein: EXPLY_DICDI
Sequence: MRTLKLIILLILSTFKTINSTNIKISECGKARCVPNGESSTDGGQCGLPLPGVIGTAALNVFAFDKGSRCGECYELTGPLGSTVVMITDGCDAGDACQQKELFNFIISKKDFNKIGNSSAYGNIYSLGYQKVSCGFSGYIKAVFGGGSIAGRPDYSYYFHVSFSNFNIGIKQVQLMGTGMSRISTLKRDLGKYTWNQEGGGAKLQFPATLILTGIDGQTLSYKFNKPPSGQMIDIKKQFAPPTQKSSSALVLRESEKKCEMGKLPDYVYQESLGLGWVTYFSWKFDYINLESHETNKKASMGKKLIQVELKGYGGLHFTREGGFQTKYIKSLSFTIRAAPPISALQVYVGQVGSYTLPTLGWQWTEITIPASKIKSKNDIEYSLSFYNNKNQTNTLWIDNIKWNFTPDCPPTPAFVTDKFI
What is the function of this protein?
May serve to lubricate the movement of the cellulose microfibrils during cell growth and wall extension and/or may serve to maintain the fluid state of the slug cell wall.
What are the official names of this protein?
Expansin-like protein DDB_G0293186.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RBSD_ECOHS
Sequence: MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_STAAR
Sequence: MHFIAISINHRTADVALREQVAFRDDALRIAHEDLYETKSILENVILSTCNRTEVYAVVDQIHTGRYYIQRFLARAFGFEVDDIKAMSEVKVGDEAVEHLLRVTSGLDSIVLGETQILGQIRDAFFLAQSTGTTGTIFNHLFKQAITFAKRAHNETDIADNAVSVSYAAVELAKKVFGKLKSKQAIIIGAGEMSELSLLNLLGSGITDITVVNRTIENAMKLAAKHQVKYDELSSLPNLLESADIVISSTSAQSYIITNEMIERIAENRKQDSLVLIDIAVPRDIEPGISAITNIFNYDVDDLKGLVDANLRERQLAAATISEQIPAEIHAHNEWVSMLGVVPVIRALREKAMAIQAETMDSIDRKLPGLSERERKIISKHTKSIINQMLKDPIKQAKELSSDKKSNEKFELFQNIFDIEAKCPHEQAKQQKESKVKEISARRIFSFE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: Y1599_CALS8
Sequence: MDMFADNVVTLVDEEGREISFEMLDKVNYNGNDYIVLLPLEEIEKEDEEAEVIILRIEDRDGEEVYVGVEDEEELENVFEIFQSRFDDEDFDMYDEEDEE
What are the official names of this protein?
UPF0473 protein Csac_1599.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: LEU1_PYRFU
Sequence: MARKIKIFDTTLRDGEQTPGVSLTVEEKIEIAKQLARLNVDVIEAGFPISSPGEFEAVKRIAREVRGPTIAALARAVKKDIDAAGEALKDAESKRIHTFIATSLIHMKYKLRKTPEEVKKMAVEAVEYATKYTDDIEFSAEDATRSDWNFLVEVYEAVIDAGATTINVPDTVGYTTPEEFYELIRYLKRNITNLNGVTISVHCHNDLGLAVANSLSAVRAGADQVEVTVNGIGERAGNAALEEVVVALDVRKDFYNVETGINLGEIARTSKLVARLTGIEVPPNKAVVGANAFAHESGIHQDGVLKERTTYEIIDPRKLGFSGSKIVLGKHSGRHAFRKKLEEMGYRLSEEEINRLFAKFKEIADRKKGLTELDIEAIVQEELGKGKGKYSVEVLHVISGKISTATVRVQGDGIDKIESAWSSNGPIDALFAAINRALGIDCKLKEYRVSSVTSGRDALGEVLVRVEYNGEIYVGRGLSTDIIEASAQAYLSALNRIRR
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: AROA_METS4
Sequence: MSHDSVPSPITARAGTPLRGRLRPPGDKSISHRAMILGLLSLGETRVEGLLEGDDVLRTAAAARALGAGIDRDGPGRWRVRGVGIGGLSDPEGVLDFGNAGTGSRLMMGVVGGQPVTATFDGDASLRKRPMRRILDPLVQMGAQILSEQAGGRVPLTLRGPEEAIPITYATPVASAQVKSAVLLAGLNAPGTTTVIEAAATRDHTERMLRLFGAEVTVAAHGPAGHGRAIALTGQPTLRAAEVIVPADPSSAAFPIVAALIVPGSDVVIEGVMMNPLRTGLITTLIEMGADIARLNERDEGGETVADLRVRASRLAGVTVPPERAPAMIDEYPVLAVAAAFAEGTTRMQGLHELRVKESDRLAAVADGLRANGVAHAVEGDDLIVHGDGRPAPGGGTVATHLDHRIAMAFLVMGLAAGEPVTVDDGAMIATSYPAFLADLRGLGAAFAE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_CLOK1
Sequence: MLKGRHLIDAMDFSIEELEEIFKLSNEIISREKEFSHICEGKLLATLFYEPSTRTRLSFESAMLRLGGKVMGFSEPGSSSASKGESIADTIRVISCYADIAAMRHPKEGAPKIAAMYSNIPVINAGDGGHQHPTQTLTDLLTVKSIKGRLSNLKIGCCGDLKFGRTVHSLIKAMSRYENNSFTLISPEELKIPNYLKKELNSKNVKYEETKNLEDSIESLDILYMTRVQRERFFNEEDYIRLKDSYILDKGKISRAAKDMIVLHPLPRVNEISYEIDKDPRAYYFKQAKYGMYVRMALMIKLLGIQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y1341_METJA
Sequence: MILKHRRPNIYGLMNKEGNKEEVEMIINELLNRDYKITFLPSGSSAVFLSMWIAKIYSNEISIPDMGGWQGFLKFPKLLNLKNNMIETNLGIIDLEKLDESLKENSSLILTSLAGYLAPQPLKEIKKLCEEREVLFIEDISGKIGGDCGYGDIVVCSTGTPKILNCEYGGFLGISKEIEEKLGNALNDIKILSKTYKTINYFGLLKEELLNAKKTYKKYVEASKIIKDEIENAYFREFEGISVFIECDNPKNISKKINSLIKLDNRKSITTICPNYDRILKNGIVFETKKIDISELNREVINEIIIALSSIL
What are the official names of this protein?
Uncharacterized protein MJ1341.
Protein: ARGC_MORPR
Sequence: MLKTILVGATGYTGAELAHYITKHPELELAGLYVSEHSLDAGKPFSSLYGHLLGVVDQTIEPLAVSNIKNICDDVDIVVLATAHEVSHDIAAEFLAQDTVVFDLSGAFRVNDPAFYENYYGFKHNFDKELQSAVYGLAEWASADIAEANLIAVPGCYPTASLSALKPLAKHGLISTDQKPIINAVSGVSGAGRKASLASAFCEVSHAPYGVFNHRHQPEISTHLGHEVIFTPHLGSFKRGILATINVKLAAGVTPEQVTAAYQEAYQDQPMVRLLPSGWPSIKAVEKTAYCDLAWQQQGQDLIVVSAIDNLLKGAAAQAMQCINIRFGFAMTTSLV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_BURCM
Sequence: MAKISKRRQAFAAKVDRQKLYAIEDALALVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEIVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEAAALRSNLSALIEALQKAKPATSKGVYLRKVALSSTMGVGLRVDQATLAAQ
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RIBA_SHEAM
Sequence: MSIKYVATSKLPTPWGVFAMHGFEDSETGKEHVALTFGDLSGDAPVLGRIHSECLTGDALFSLRCDCGFQLQTAMQRIAETGRGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFAADMRKYDMIAPMLAHLGISRVKLMTNNPRKVNAMKDVGMDVVERVPLQVGKNRYNEAYLKTKSDKLGHMMSEEHFKAQHQD
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: RUVB_CERSK
Sequence: MTSSDPTLRPERLPEDMDRALRPQSLEEFVGQAEARANLRVFIESARMRGEAMDHTLFHGPPGLGKTTLAQIMARELGVGFRMTSGPVLAKPGDLAAILTNLEPRDVLFIDEIHRLSPVVEEVLYPALEDFALDLVIGEGPAARTVRIDLQPFTLVGATTRLGLLTTPLRDRFGIPTRLQFYTEDELDLIVARGARMMGVDSDPEGTREIARRARGTPRIAGRLLRRVVDFALVEGDGRLTQAIADRALTRLGVDHLGLDLGDRRYIGLIAENYGGGPVGIETIAAALSESRDAVEEVIEPYLLQQGLIQRTPRGRMLAHKAWRHMGIEPPKGPGQSDLFG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NOEK_SINFN
Sequence: MGPKFGTSGLRGLATELVGSVSALYATAFSRMLLDRGRVAPGATVLVGRDFRDSSSEIAAICMAALARAGMVPVDCGGLPTPALALYGRKLGAASLMITGSHIPADRNGIKFYLPDGEINKADEQAITALAEQLSADADATRVECGRGADHSSEATDFYIQRYETLLPKSGLKGLKIGLYQHSSVARDILTTILEGHGANVVPVGRSEVFIPVDTEAISAATCKMLAAWAKEFAFDAIVSSDADADRPLLTDETGTPLRGDLLGLICARLLEAKLIATPITSNSGIEAASGVEVVRTRVGSPYVIAAMTEAVARGKQRVMGFEANGGVMLGSNFSFGGASLPALPTRDCVLPIIAALHMAVEAKTPLSGIVAMHRLPVALSGRIENYPFDRSDALVAFLKASKANVSHLFSRIGRVAGTDDVDGLRLTFEGGRILHIRPSGNAPELRCYVEADDPDAAEHLLAQGLAVLNSSMV
What are the official names of this protein?
Phosphomannomutase, PMM.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RHBL4_HUMAN
Sequence: MQRRSRGINTGLILLLSQIFHVGINNIPPVTLATLALNIWFFLNPQKPLYSSCLSVEKCYQQKDWQRLLLSPLHHADDWHLYFNMASMLWKGINLERRLGSRWFAYVITAFSVLTGVVYLLLQFAVAEFMDEPDFKRSCAVGFSGVLFALKVLNNHYCPGGFVNILGFPVPNRFACWVELVAIHLFSPGTSFAGHLAGILVGLMYTQGPLKKIMEACAGGFSSSVGYPGRQYYFNSSGSSGYQDYYPHGRPDHYEEAPRNYDTYTAGLSEEEQLERALQASLWDRGNTRNSPPPYGFHLSPEEMRRQRLHRFDSQ
What is the function of this protein?
Intramembrane-cleaving serine protease that cleaves single transmembrane or multi-pass membrane proteins in the hydrophobic plane of the membrane, luminal loops and juxtamembrane regions.  Involved in regulated intramembrane proteolysis and the subsequent release of functional polypeptides from their membrane anchors.  Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded membrane proteins.  Required for the degradation process of some specific misfolded endoplasmic reticulum (ER) luminal proteins.  Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner.  Functions in BIK, MPZ, PKD1, PTCRA, RHO, STEAP3 and TRAC processing.  Involved in the regulation of exosomal secretion; inhibits the TSAP6-mediated secretion pathway.  Involved in the regulation of apoptosis; modulates BIK-mediated apoptotic activity.  Also plays a role in the regulation of spermatogenesis; inhibits apoptotic activity in spermatogonia.
What are the official names of this protein?
Rhomboid-related protein 4, RRP4, Rhomboid domain-containing protein 1, Rhomboid-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Mitochondrion membrane; Multi-pass membrane protein.
Protein: RPAC2_DROME
Sequence: MGALAELAGDEKNGEGSRTFVFTNEGHTLGNALKTIIARYPEVDFCGYTIPHPTEQKLHFRIQSRRDRAIDILKRGLEDLEGLCDHTIVTFEKEMAEFNAMKVEN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively (By similarity).
What are the official names of this protein?
Probable DNA-directed RNA polymerases I and III subunit RPAC2, RNA polymerases I and III subunit AC2, AC19, DNA-directed RNA polymerase I subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_SYNWW
Sequence: MPRKGPVPKRDVLPDPIYNSKIFTKLVNQLMWDGKKSLAEKICYGAFAIVQSKTRREPLEVFEEAMKNITPIVEVRARRVGGANYQVPVEVRSDRRQTLAIRWLVGYARKRGEKTMAERLAGEIMDAANHTGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: LDH_STRPN
Sequence: MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELFEGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIGQPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CORE5_ADECR
Sequence: MAAISRAIKQELLEDLKPEMYLPPKSTRRRAKVKTEEKVDVKTLVKSKSKKRRAAKNELEENVEFVRRFAPRRPYQWRGRQVRALPRPGIPVVFTPGQRSGVASKRSYDEVYADEDVLDQSGNMINEFAYGKRVKMLTHKNPTPSQVPITPQEPIARPGEARLLPTVQVLAPRDSKHETMLPVTKSEGGDVKVENKGFEQITPQLGVQTVDIKVPVKRKSEVEDEILKRAKMEPFETTVKMEYSEQPQVEVFDTGVEPSSFFEVRSQARPIAVARKRRVPTVEVMEVQQSDHTAPTASAAPVANVIVGPHLSRRPSRWGPANAIYPDYVYHPSISAKKIMGPRPTGRVSRWGPANSIFPEVRLHPSMVSAVTRAAPRKSTKSRRRRRVRTRRAFVLPAGTKTGVMLPQNIRYHPSILFRRA
What is the function of this protein?
Associates loosely with the viral DNA to form an outer shell around the nucleoprotein-DNA complex and links it with the capsid by binding the endosome lysis protein.  Dissociates from the viral genome during entry.  Might be involved in nuclear capsid assembly of the viral particles through its association with NPM1/nucleophosmin.
What are the official names of this protein?
Core-capsid bridging protein, Core protein V.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae core-capsid bridging protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=Located inside the capsid (core). Present in 157 copies per virion. Localizes in the nucleoli during infection, then translocates from the nucleoli to the nucleoplasm as the infection progresses and is finally incorporated into the viral particles.
Protein: MZM1_AJECH
Sequence: MAATTAPNPLTAYRFLLRATRIAFQGDFTTLHAARAEARKQFDQHRQQGVDTPMRIQHAMETAEILRTNVVQGVKISGAGEEAERYASILVMRRFRGEYEGEDERREKEEAMRELRIHEHIERGDNDSIKTAGKNERVKVAVGKACSNMQSSE
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CRBN_DROSE
Sequence: MDEEENSEINSVQARNEDVQLEDQSQSQGLQDRQVDAIEQAWNDAMPDEPSPPAEYAFQDPLAIVGEGGDAPEAMVEDVLQDDTVSEGSHPSSDMSLESPGSEDDSDVQGLPNWMIPQNRLRSAVDMMVSQARNRDGGIAALLSGDNFLQRVRSMVFSQERRRSRTSEETSQEEAAEEPDDPPPQQPPLPPIDIGFDTNLPAEHSYFGNHLSRVPGVDYLEVGSVHHMLIFLHHHILFPGEVLPFMIDGQMFDDDMPGLDGLIFGVSFPRLQPPEDNPHKLYGVTCQIYERGESGRGLVFYKSRALQRIVINCDDIKGSPQYIARNPTNKCFSKVKILPEYFLPEPLQSVDMGSMARFRDIPSMRDKYRRFQLSTTTWPSDACQEYSFASIVERARQRLESQKIDTMPKCPIQLSFWLVRNLHLTEKMMRLTFLTDSVNTRLQLIKSTFKDETLFFCRYCNSSLALCSDLFAMSKHGVQTQYCNPEGYIHETNTVYRVISHAIGYSGEPSTKFSWFPGYQWHIILCKFCAQHVGWEFKAVLPNLTPNVFFGLSGSSVRIGKASEYSPFNGTTYVVRNMLRMISSDME
What is the function of this protein?
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Has an essential role in mediating growth by negatively regulating insulin signaling.  It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
What are the official names of this protein?
Protein cereblon, Protein ohgata.
What is the protein family that this protein belongs to?
Belongs to the CRBN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS8_LACLS
Sequence: MSWQNNLHSVSPYIAGEQPELTDMIKLNTNENPYQPSLQVQKVIEDFKSENLRLYPSTDAKFLRKALAEYHHLNTDQVFIGNGSDEVLSLSFLTFFNGQRAILMPDISYSFYPIYCELYRIPYQKIPLADDFSLSVNSYFQENGGIVIANPNAPTGMAISLQEIEEILQNNQDSIVLIDEAYIDFGGESCLPLLEKFDNLVVVQTFSKSRSLAGIRLGIAFGSAEAIAHLYDVKNSFNSYPIDSLAQKIGEASFTDETYFQKSVSKIITTRENFKNELIKLGFQVTDSKTNFVFVHHPKIDATTLFKVLYEAKIIVRHWNQARISDWLRITIGTDREMNTVIQFLKEYLKNKEKSY
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: CPNE7_HUMAN
Sequence: MSAGSERGAAATPGGLPAPCASKVELRLSCRHLLDRDPLTKSDPSVALLQQAQGQWVQVGRTEVVRSSLHPVFSKVFTVDYYFEEVQRLRFEVYDTHGPSGFSCQEDDFLGGMECTLGQPAQKWLLQVVMRVSVDVLGPAGHCAKHFLCCTESSHLARTGPSFLLRYDDLCLPWATAGAVRWWTCRGGHTQGWQIVAQKKVTRPLLLKFGRNAGKSTITVIAEDISGNNGYVELSFRARKLDDKDLFSKSDPFLELYRVNDDQGLQLVYRTEVVKNNLNPVWEAFKVSLSSLCSCEETRPLKCLVWDYDSRGKHDFIGEFSTTFEEMQKAFEEGQAQWDCVNPKYKQKRRSYKNSGVVVLADLKFHRVYSFLDYIMGGCQIHFTVAIDFTASNGDPRNSCSLHYINPYQPNEYLKALVSVGEICQDYDSDKRFSALGFGARIPPKYEVSHDFAINFNPEDDECEGIQGVVEAYQNCLPRVQLYGPTNVAPIISKVARVAAAEESTGKASQYYILLILTDGVVTDMADTREAIVRASRLPMSIIIVGVGNADFTDMQVLDGDDGVLRSPRGEPALRDIVQFVPFRELKNASPAALAKCVLAEVPKQVVEYYSHRGLPPRSLGVPAGEASPGCTP
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.
What are the official names of this protein?
Copine-7, Copine VII.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane. Note=Translocates to the cell membrane in a calcium-dependent manner (PubMed:21087455).
Protein: ACP_LISMC
Sequence: MAEVLEKVTKIIVDRLGVEESKVTLEASFKEDLGADSLDVVELVMELEDEFGVEISDGDAENINTVGDAVKYIEANA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_ECO24
Sequence: MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: DTD_PARP8
Sequence: MIALIQRVRRAEVRVGDRVTGAIDAGLLALVCAERGDTDAVADKLLAKVLGYRVFSDAAGKMNLPVQNIDGAGRAGGLLLVSQFTLAADTNSGLRPSFTPAAPPDEGKRLFDYFVAAARAKHAIVETGEFGAEMQVSLVNDGPVTFWLQTRA
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAF1J_ARATH
Sequence: MAETLKEDSIMIREVWDYNLVEEFALIREIVDKFSYIAMDTEFPGVVLKPVATFKYNNDLNYRTLKENVDLLKLIQVGLTFSDENGNLPTCGTDKFCIWQFNFREFNIGEDIYASESIELLRQCGIDFKKNIEKGIDVVRFGELMMSSGIVLNDAISWVTFHGGYDFGYLVKLLTCKELPLKQADFFKLLYVYFPTVYDIKHLMTFCNGLFGGLNRLAELMGVERVGICHQAGSDSLLTLGSFRKLKERYFPGSTEKYTGVLYGLGVEDGTTTTVAN
What is the function of this protein?
Ubiquitous transcription factor required for a diverse set of processes.  It is a component of the CCR4 complex involved in the control of gene expression (By similarity).
What are the official names of this protein?
Probable CCR4-associated factor 1 homolog 10.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LPLT_ECOLC
Sequence: MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLADWHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: METE_HALH5
Sequence: MLTSNLGYPRIGENREWKKALESFWANDTTEEQLLATMKELRLNHLRVQQEQEVDLIPVGDFTLYDHVLDMAVMFGIIPKRFLQQGDTPTLSTYFAMARGSKNAQACEMTKWYNTNYHYIVPELHDAAPRLTKNAPLEAYLEAKNELGIDGKPVILGPYSFVKLAKGYEEDKLQETIQSLLPLYIQVIQELVDAGARSIQVDEPSLVTSISAREMALVTRIYEQINEAIADAPLFLQTYFDAVTFYEEVVSLPVKGIGLDFVHGGAKNLEALRTFGFPEDKVLAAGIIDGRNIWISNLRERHELVHQLEQHVAKDRLVLQPSCSLLHVPVTTKREEKLDPTLLGVLAFANEKLTELHTLKQLAAGNEAEVKEALEANDDALAALEKSGWRSGAATSHNLENKKRPQSFNERRPLQEEKWQLPLLPTTTIGSFPQTKDVRRTRSLWRKGELSTVEYERTMKSYIEKWINIQEELGLDVLVHGEFERNDMVEFFGEKLDGFAFTANGWVQSYGSRCVKPPIIYGNVSFTEPMTVAETVYAQSLTDKPVKGMLTGPVTILNWSFVRDDLPLTVIAHQIAEALTHEVTALEEAGIEMIQIDEPAIREGLPLKAEDQQEYLDWAVSAFRASCAHVKATTQIHTHMCYSEFHEMIEAIDDLDADVISIETSRSHGEMISAFEKTTYEKGIGLGVYDIHSPRVPSEEEMLNVIRRALTVLPASLFWVNPDCGLKTRAEKETVAALKNMVAAARAAREELKTKA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.