PharMolix/UniProtQA huggingface dataset:
Protein: MURE_ENTFA
Sequence: MTISLFAIRDCLEKEDLLKEFISPEGWHLTLSDTLGQREVTALSYDSRDVTAETLFFCKGLNFKEIYLENAVKDGLEIYVSEVPYEVPAQLGIIVTDIKKAMAVLSMAFYDYPQNKLKLIGFTGTKGKTTAAYFTKYILDVATQQKTALLSTMNSTLDGKTFFKSALTTPESLDLYRMMATAVANGMTHFIMEVSSQAYKTNRVYKLFFDVGIFLNITPDHISPIEHPTFDDYFYCKRQLITHSKVIVLNHEADYFPLLKETAQQQKVPAIVYGSQPAPEVDYSFAVSSEDSLRFIVESPADALGLAGSYHLRLGGDFNKGNALSAAIASVLVGASKEECQQGIAATTVPGRMESLTNTNGATVYVDYAHNYDSLKNLLTFVREEHPDGRLIVLVGSTGDKAISRRKDFGRVLSELADVAVLTTDDPASEDPAKICQEIQAHITKEMPVYTVLDRGEAIAHALSLSTTADDAIVLAGKGADLYQKVNGVDEPYAGDFALAEAFINKKN
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP5G_STAA8
Sequence: MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: BUD4_VANPO
Sequence: MIPNDAEGAMDSLLKEIDHEMEVTIGTIDAQEDHSKQKEETEATNQQTWKLPLQDIGDETMDMLVKHNTKNNVINPNFNKKDVDTNESPKNNNDKNVVFNDNVQLLELSANMDESVLMSTPTKSDIDISPNKVLINLGDDIANESNEDNKLPLDNKTESEDSDLVSTMLLSKIPITHTENINDFYEKKSTDIRASTSRISSVSSDIEGTPLPTTVQTDQFELLKQAMKQTFEEDNNSNIDISPLKESLLSSELKTKQNLSIEQNEETSVDSIDNSVIHNSEYEVHARSNEREEENENDFENSIEDLEISTHVIEKSPSIEAISTLDPNTDNNKEHFIINNITKDSTFIEVTSDSKIQIDLKDSPENTLHTNEDQKEANTENVASETNIKETDQVIHIPTLTEEEISTITNITNDTETTEEGSKAEEDAKNSDVSNSQNSESINTTITNSLIGIDQNLTNKSSDITNDYEEPPKENELKSSPDVIEKGHSSIEHFDDEKITNSSALGTSNYISIPLDTLQEATPVTDSGKTFELQNQDSDNINSERIQNLNGSTPVEEKFNADDELLKTNQSHITQNKDKSNINEIDNSGTTSIVSDHVVAPILPPLPKIDKIFIDDPFGEEYDISNDSIDLTKSTRPGDYLSIWHIQEEELKQVSPASTTNSQFSNRILSNASSNASAESRISSTAFKFKPRIVSRSRYINPESRVNSFNISEEMILPQLYGALDPMRRSSRMSRTIQNSIKANRQKSEQYAGTRKYSIEIQPNQESRISSRIISNKLEEVSSENDKVETMNNSITMDGSFQLLPSFLDNSFGEQLDLTFSKFAKDVLSLRSSSLAQSEIHDNSINIWGEDNFIGNTSKNNDHNAMLDSKNKLLEVTDDEKSISESINKDIFADGILKSSIFNDITVSRGLNINGLDVDLSDSESVRVSLLTAETDASESGTPIKNTVKDSHVSSPFKVVNISKWKNQDGPESDHEVEEIAEIQIEAEKSSESIADISPIKMKPFVDTVVIEEPSQTALVDAGSLYLKLKGCLNIKLTGIKHHDARYCFEFDNGRNSIQTAWAVIPSDGDIRVNHDFESTVFEVGSKLYVTLKCKYTPPKTEIVEVVEKVLIPKKKLFGKAEYKYEKRFVQRDSKKDEWNNLFARDGSFGRAEVLLDHTFLNSVKYNKRNCTFDMMNEWTRLNDKENIENVFNIPRKPKYKVADLKMEVCYLDRVSNKEVFPVSFDKCEMIIKKYKEQLLISKEGYLMQEGGDVCNNLVRRFFKLQGTDLIGYHEVSNLPVVTINMLKVIDVVSSDDLKEEEGKQRSGNSKRNFTDHVLFGGCIQLVFTDEEVINLYADTSAQEKIEWYSKLKKTVDLNICHQPWVTKLAEAQKLEEC
What is the function of this protein?
Required for selection of future bud sites.  Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate budding and cytokinesis.  Involved in the septin organization at the bud neck (By similarity).
What are the official names of this protein?
Bud site selection protein 4.
What is the protein family that this protein belongs to?
Belongs to the BUD4 family.
What are the subcellular locations of this protein?
Bud neck. Note=Localizes to two distinct rings on either side of the mother-bud neck.
Protein: RPOC_THET8
Sequence: MKKEVRKVRIALASPEKIRSWSYGEVEKPETINYRTLKPERDGLFDERIFGPIKDYECACGKYKRQRFEGKVCERCGVEVTKSIVRRYRMGHIELATPAAHIWFVKDVPSKIGTLLDLSATELEQVLYFSKYIVLDPKGAILNGVPVEKRQLLTDEEYRELRYGKQETYPLPPGVDALVKDGEEVVKGQELAPGVVSRLDGVALYRFPRRVRVEYVKKERAGLRLPLAAWVEKEAYKPGEILAELPEPYLFRAEEEGVVELKELEEGAFLVLRREDEPVATYFLPVGMTPLVVHGEIVEKGQPLAEAKGLLRMPRQVRAAQVEAEEEGETVYLTLFLEWTEPKDYRVQPHMNVVVPEGARVEAGDKIVAAIDPEEEVIAEAEGVVHLHEPASILVVKARVYPFEDDVEVSTGDRVAPGDVLADGGKVKSDVYGRVEVDLVRNVVRVVESYDIDARMGAEAIQQLLKELDLEALEKELLEEMKHPSRARRAKARKRLEVVRAFLDSGNRPEWMILEAVPVLPPDLRPMVQVDGGRFATSDLNDLYRRLINRNNRLKKLLAQGAPEIIIRNEKRMLQEAVDALLDNGRRGAPVTNPGSDRPLRSLTDILSGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKRMALELFKPFLLKKMEEKGIAPNVKAARRMLERQRDIKDEVWDALEEVIHGKVVLLNRAPTLHRLGIQAFQPVLVEGQSIQLHPLVCEAFNADFDGDQMAVHVPLSSFAQAEARIQMLSAHNLLSPASGEPLAKPSRDIILGLYYITQVRKEKKGAGLEFATPEEALAAHERGEVALNAPIKVAGRETSVGRLKYVFANPDEALLAVAHGIVDLQDVVTVRYMGKRLETSPGRILFARIVAEAVEDEKVAWELIQLDVPQEKNSLKDLVYQAFLRLGMEKTARLLDALKYYGFTFSTTSGITIGIDDAVIPEEKKQYLEEADRKLLQIEQAYEMGFLTDRERYDQILQLWTETTEKVTQAVFKNFEENYPFNPLYVMAQSGARGNPQQIRQLCGLRGLMQKPSGETFEVPVRSSFREGLTVLEYFISSHGARKGGADTALRTADSGYLTRKLVDVTHEIVVREADCGTTNYISVPLFQPDEVTRSLRLRKRADIEAGLYGRVLAREVEVLGVRLEEGRYLSMDDVHLLIKAAEAGEIQEVPVRSPLTCQTRYGVCQKCYGYDLSMARPVSIGEAVGIVAAQSIGEPGTQLTMRTFHTGGVAGAADITQGLPRVIELFEARRPKAKAVISEIDGVVRIEETEEKLSVFVESEGFSKEYKLPKEARLLVKDGDYVEAGQPLTRGAIDPHQLLEAKGPEAVERYLVEEIQKVYRAQGVKLHDKHIEIVVRQMMKYVEVTDPGDSRLLEGQVLEKWDVEALNERLIAEGKTPVAWKPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGSDFVRFTQVVDQKTLKAIEEARKEAVEAKERPAARRGVKREQPGKQA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: UPP_GEOKA
Sequence: MGKVYVFDHPLIQHKLTYIRDKNTGTKEFRELVDEVATLMAFEITRDLPLEEVEIETPVSKARAKVIAGKKLGVIPILRAGIGMVDGILKLIPAAKVGHIGLYRDPQTLKPVEYYVKLPSDVEERDFIIVDPMLATGGSAVAAIDALKKRGAKSIKFMCLIAAPEGVKAVETAHPDVDIYIAALDERLNDHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NAGB_LACJO
Sequence: MKIIVTKDNIEGGTKAFEIIKKGMEDGDKVLGLATGSSPIPLYDDMCDSDLDFSDMTSINLDEYYGLNPDNDQSYHYFMQKHLFDKKPFKHSYIPNGMAKDIDEEVDRYNDIIAANPIDIQILGIGRNGHIAFNEPGTPFGSLTHKVQLTESTIKANSRFFDNEDEVPRQAICMGIKSIMQSKKIVLLAFGESKQDAVKALVEGPVTEEVPASILQDHPDVTVICDEVAAAKLDPKYRN
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: TRPC_BURP6
Sequence: MSDILDKIIAVKREEIAAALESAPLEELKVQASARDSRDFVGALRDKHAAGHAAVIAEVKKASPSKGVLREHFVPADIARSYAQHGAACLSVLTDERFFQGSARYLEQARAACALPVLRKDFIVDAYQVLEARAMGADAILLIAAALDTPLMIDLEAYAHSLGLAVLVEVHNRSELDEALKLKTPLVGINNRNLRTFETTIDTTLGMLDAIPDDRIVVTESGILSRADVERMEAAGVHTFLVGEAFMRAENPGAELARMFF
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ASSY_CLOB8
Sequence: MIKYNKVVLAYSGGLDTSIIIPWLKENYGCEVIAVCGNVGQKDELDGLEEKAIKTGASKLYIEDLTQEFVDDYIFPTIQAGAIYEGKYLLGTSFARPIIGKRLVEIAKAEGADAICHGCTGKGNDQVRFEMAVKAFAPEMPIIAPWRIWDIKSREDEIDYAEAKNVPLKINRETNYSKDKNIWHLSHEGLDLEFPENEPQYDKILELCKTLEAAPNEATYITLSFENGIAIALNGKKMNSVELLDELNKIGGENAIGITDMVENRLVGMKSRGVYETPGGTILYKAHKDLEELCLDKETAHYKEQIALKFADLVYNGQWFTPLREALTEFVNKTQETVTGEIKLKLYKGNIVNAGMTSPYSLYSEEYATFGEDGVYDQKDSAGFINLYGLPTVVKAKMQEKIKKEEM
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM33_CAEEL
Sequence: MVEIVEEPDDHQSSSTGAGSSGSSSAPPPPPPPAYSSISQYVSANTMECVLFAARVLTVFFALNYMIPFIGLVPAHSAYYKIFAASAATFALRLHTRIQGQFALNAQFIQRLIIEDSFHYLVYSVVFLMAAPVSMAALPVTIYAALHACTFMTKILRETGHTSSIIPKLEQFTAHQTQNALGIIACSEIFLVPLLVSLIFSGKGSLLLPFAYYRFLSLRYASRRNPSTRQAFAQMRGSLQNVAMSSSCPRPISSLIYRAIDFISARAPPVM
What are the official names of this protein?
Transmembrane protein 33 homolog.
What is the protein family that this protein belongs to?
Belongs to the PER33/POM33 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NDK_MYCLE
Sequence: MTERTLVLIKPDAVERQLIGEIISRIERKGLTIAALELRQVGEELASQHYAEHESKPFFGSLLEFITSGPVMAAIVEGPRAVAAVRQLTGGTDPVEKAAPGTIRGDLALETQFNLVHGSDSTASAQREIALWFPGI
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBL2_ORYSJ
Sequence: MALVEGNNGVSGGAVSFSEEQEALVLKSWAIMKKDSANIGLRFFLKIFEVAPSASQMFSFLRNSDVPLEKNPKLKTHAMSVFVMTCEAAAQLRKAGKVTVRDTTLKRLGATHFKYGVGDAHFEVTRFALLETIKEAVPVDMWSPAMKSAWSEAYNQLVAAIKQEMKPAE
What is the function of this protein?
May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule.
What are the official names of this protein?
Non-symbiotic hemoglobin 2, ORYsa GLB1b, rHb2.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: MGSA_BACCR
Sequence: MKIALIAHDKKKNDMVSFAYAYKPIFEQHELFATGTTGLRIMEATGLVITRYQSGPLGGDQEIGAMIAKNDLDMVIFFRDPLTAQPHEPDVNALLRLCDVYAIPLATNMASAEMLMHALERGDLDYRKLRK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: NCAP_I01A1
Sequence: MASQGTKRSYEQMETGGERQNATEIRASVGRMVGGIGRFYIQMCTELKLSDYEGRLIQNSITIERMVLSAFDERRNKYLEEHPNAGKDPKKTGGPIYRRRDGKWVRELILYDKEEIRRIWRQANNGEDATAGLTHLMIWHSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRRTRIAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFLARSALILRGSVAHKSCLPACVYGLAVASGYDFEREGYSLVGIDPFRLLQNSQVFSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRGTRIVPRGQLSTRGVQIASNENMDTMDSNTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFERATIMAAFTGNTEGRTSDMRTEIIRMMESARPEDVSFQGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEFEN
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: ILVC_LEUMC
Sequence: MTTKMFYDKDIDTKPLENKKIAVIGYGAQGHAQANNLRVSGFDVIMGLRPGKSFDSVKKDGFEVYSAAEATAQADVVMMETPDELQAAVWEKEVEPNLKAGSDLGFSHGFNIVYGLIKPNADINVMIIAPKGPGNIERRQFVEGGGIPSLYGVHQDPTGDTAEVAKAYAKGIGSGCAGILETTFEEETTEDLFGEQAVLCGGLTQLIEAGFNTLVEAGYSPELAYFETSHEMKMIVDLIFEGGFEKMRHDCSNTCEYGEMLNGPRIITEESKQGMRDVLKDIQDGTYAKKWLAEYNSGLKDLEKMRTEYKSGLYEQTGKKVRAMMPWISDADKYSTAADTEQFSAAK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: NOC3L_PONAB
Sequence: MKARRNKKQIPSFRKLIKTSKVKPENKLKNKQFKQQSTLKKYRKEQRKLRQAVKDAVSKKPIPLENPKEKRPGKRIEREEEEEEEALPLDMMDEDDLQLMKDLGQRASFLTRDLSSSEPVHAKKRKHKRIIDKYEKIPRTLQTVPEKELIHLLPIKDKSGIIPQTREKPVTDSNKDEEDQEEERELEEEIIEDPIQELTIEEHLIERKKKLQEKKMHIAALASAILSDPESNIKKLKELRSMLMEQDPDVAVTVRKLVIVSLMELFKDITPSYKIRPLTEAEKSTKTRKETQKLREFEEGLVSQYKFYLENLEQMVKDWKQRKLKKSNVVSLKAYKGLAEVAVKSLCELLVALPHFNFHNNIIVLIVPLMNDMSKSISEMCCEAVKKLFKQDKLGQASLGVIKVISGFVKGRKYEVRPEMLKTFLCLRIKEVEVKKDTEDINKPKKFMTFKEKRKSLSRMQRKWKKAEEKLERELREAEASESTEKKLKLHTETLNIVFVTYFRILKKAQRSPLLPAVLEGLAKFAHLINVEFFDDLLVVLHTLIESGDLSYKESLHCVQTAFHILSGQGDVLNIDPMKFYTHLYKTLFKLHAGATNEGVEIVLQCLDVMLTKRRKQVSQQRALAFIKRLCTLALHVLPNSSIGILATTRILMHTFPKTDLLLDSESQGSGVFLPELDEPEYCNAQNTALWELHALRRHYHPIVQRFAVHLIAGAPSEGSGALKPELSRRSAAELFEAYSTAEMTFNPPVESSNPKIKGKVLQGDSFLNEDLNHLIKRYSSEVATESPLDFTKYLKTSLH
What is the function of this protein?
May be required for adipogenesis.
What are the official names of this protein?
Nucleolar complex protein 3 homolog, NOC3 protein homolog, NOC3-like protein, Nucleolar complex-associated protein 3-like protein.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus speckle. Note=Localizes to nuclear speckles.
Protein: MIEN1_BOVIN
Sequence: MSGDTGTTSVAPPPGETEPGHGVRIVVEYCEPCGFEATYLELASAVKEQYPGIEIESRLGGTGAFEIEINGQLVFSKLENGGFPYEKDLIEAIRRASNGEPLEKITNSRPPCVIL
What is the function of this protein?
Increases cell migration by inducing filopodia formation at the leading edge of migrating cells.  Plays a role in regulation of apoptosis, possibly through control of CASP3.  May be involved in a redox-related process (By similarity).
What are the official names of this protein?
Migration and invasion enhancer 1.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Lipid-anchor; Cytoplasmic side. Note=Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions (By similarity).
Protein: RNH_YERPS
Sequence: MTKQVEIFTDGSCLGNPGPGGYGAILRYKQHEKTFSAGYYLTTNNRMELMAAIVALEALTSPCEVTLSTDSQYVRQGITQWIHNWKKRGWKTADRKPVRNVDLWQRLDLAIQSHTIQWEWVKGHAGHPENERCDELARQGANSPTLDDTGYNPD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA1_STRAW
Sequence: MSVLSKIMRAGEGKILRKLHRIADQVNSIEEDFVDLSDAELRALTDEYKQRYADGESLDDLLPEAFATVREAAKRVLGQRHYDVQMMGGAALHLGYVAEMKTGEGKTLVGTLPAYLNALSGDGVHLITVNDYLAERDSEMMGRVHKFLGLSVGCILANMTPAQRREQYGCDITYGTNNEFGFDYLRDNMAWSQDELVQRGHNFAVVDEVDSILVDEARTPLIISGPADQATKWYGDFAKLVTRLKKGEAGNTLKGIEETGDYEVDEKKRTVAIHESGVAKVEDWLGIDNLYESVNTPLVGYLNNAIKAKELFKKDKDYVVIDGEVMIVDEHTGRILAGRRYNEGMHQAIEAKEGVDIKDENQTLATITLQNFFRLYNKLSGMTGTAMTEAAEFHQIYKLGVVPIPTNKPMVRKDQSDLIYRTEVAKFDAVVDDIAEKHEKGQPILVGTTSVEKSEYLSQQLSKRGIQHEVLNAKQHDREATIVAQAGRKGAVTVATNMAGRGTDIKLGGNPDDLAEAELRQRGLDPEEHIEEWAAALPAALERAEKAVKAEFEEVKELGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLGDDLMRLFKAQMVERVMSMANVPDDVPIENKMVTRAIASAQSQVETQNFETRKNVLKYDEVLNRQREVIYGERRRVLEGEDLQEQIHHFMDDTIDAYIEAETAEGFAEEWDLDRLWGAFKQLYPVKVTVDELEEAAGDRAGLTAEFISESIKDDIHEQYEQRETQLGSEIMRELERRVVLSVLDRKWREHLYEMDYLQEGIGLRAMAQKDPLVEYQREGFDMFTAMMDGIKEESVGYLFNLEVQVEQQVEEVPVEDEKPSLEKEDAVPAQAGARPEIRAKGLEAPQRPDRLHFSAPTVDGEGGIIEGDFSSDDDEEPVRSEADGLTRAERRKQSKGGRRRKK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: NLRP3_RAT
Sequence: MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW
What is the function of this protein?
Independently of inflammasome activation, regulates the differentiation of T helper 2 (Th2) cells and has a role in Th2 cell-dependent asthma and tumor growth.  During Th2 differentiation, required for optimal IRF4 binding to IL4 promoter and for IRF4-dependent IL4 transcription.  Binds to the consensus DNA sequence 5'-GRRGGNRGAG-3'.  May also participate in the transcription of IL5, IL13, GATA3, CCR3, CCR4 and MAF.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Inflammasome. Endoplasmic reticulum. Secreted. Nucleus. Note=In macrophages, under resting conditions, mainly located in the cytosol, on the endoplasmic reticulum. After stimulation with inducers of the NLRP3 inflammasome, mitochondria redistribute in the vicinity of the endoplasmic reticulum in the perinuclear region, which results in colocalization of NLRP3 on the endoplasmic reticulum and PYCARD on mitochondria, allowing the activation of inflammasome assembly. After the induction of pyroptosis, inflammasome specks are released into the extracellular space where they can further promote IL1B processing and where they can be engulfed by macrophages. Phagocytosis induces lysosomal damage and inflammasome activation in the recipient cells. In the Th2 subset of CD4(+) helper T-cells, mainly located in the nucleus. Nuclear localization depends upon KPNA2. In the Th1 subset of CD4(+) helper T-cells, mainly cytoplasmic.
Protein: Y1128_SYNY3
Sequence: MEAFFLFFLVFFGSAIGTSVKIVNEKNEYLVERLGSYNKKLTPGLNFTVPILDRVVFKQTTREKVIDIPPQSCITKDNVAITADAVVYWRIIDMEKAYYKVENLQSAMVNLVLTQIRSEIGKLELDQTFTARTEINELLLRELDISTDPWGVKVTRVELRDIMPSKAVLDSMELQMTAERKKRAAILTSEGQRDSAINSAQGDAQARVLEAEAKKKAAILNAEAEQQKKVLEAKATAEALSILTEKLSSDNHAREALQFLLAQQYLNMGTTIGSSDSSKVMFLDPRNILSTLEGVRSIVGDGALDEGLEAALNKVDRHRAV
What are the official names of this protein?
Uncharacterized protein slr1128.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y014_HIS1I
Sequence: MEYRYYCHSSFRFLKGGDGETGRWQGQFATLDSFSHYRLSLSLLAACSRW
What are the official names of this protein?
Uncharacterized protein ORF14.
Protein: MURA_SHESH
Sequence: MDKLKIEASEALAGNVVISGAKNAALPILMAGVLAETDFVVSNVPNLRDVKTSCELLRCLGAEVSRGDNSEVRISTTSLDHFCAPYDLVKTMRASILILGPLLARFGTADVSLPGGCAIGARPVNLHLHGLEQMGAKIEVEEGYIKARVDGRLKGAHIFMDMISVGATENLLMAATLADGETIIENAAREPEVIDLANCLIAMGAKIEGAGTDSIRIQGVESLKGCHYRVMPDRIETGSFLIAAAVTRGKIRCVDADPSTLEAVLAKLEDAGASITTGSDWIELDMQGKRPKAVNIKTVPYPGFPTDMQAQFCLLNVLAEGTSTITETIFENRFMHVPELIRMGANMELEGNTCIIQGIERLNGAQVMATDLRASASLVIAGLVADGTTIVDRIYHLDRGYEHIEDKFKGLGGHVERTQ
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y919_KLEP7
Sequence: MDHRLLEIIACPVCNGKLYYSQDKQELICKLDSLAFPLRDGIPVLLETEARPLALEESHS
What are the official names of this protein?
UPF0434 protein KPN78578_09190.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: EFTU_SYNP6
Sequence: MARAKFERTKPHANIGTIGHVDHGKTTLTAAITTVLAKAGMAKARAYADIDAAPEEKARGITINTAHVEYETGNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPNIVVFLNKEDMVDDAELLELVELEVRELLSSYDFPGDDIPIVAGSALQALEAIQGGASGQKGDNPWVDKILKLMEEVDAYIPTPEREVDRPFLMAVEDVFTITGRGTVATGRIERGSVKVGETIEIVGLRDTRSTTVTGVEMFQKTLDEGLAGDNVGLLLRGIQKTDIERGMVLAKPGSITPHTKFESEVYVLKKEEGGRHTPFFPGYRPQFYVRTTDVTGAISDFTADDGSAAEMVIPGDRIKMTVELINPIAIEQGMRFAIREGGRTIGAGVVSKILQ
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.