PharMolix/UniProtQA huggingface dataset:
Protein: H3E01_CYRHA
Sequence: MKASMFLALAGLVLLFVVGYASESEEKEFPIELLSKIFAVDVFKGEERGCKGFGDSCTPGKNECCPNPACSNKHKWCKVYLGK
What is the function of this protein?
Lethal neurotoxin.  Selectively blocks tetrodotoxin-sensitive voltage-gated sodium channels (Nav).  Does not affect tetrodotoxin-resistant voltage-gated sodium channels or calcium channels (By similarity).
What are the official names of this protein?
Mu-theraphotoxin-Hhn2m, Mu-TRTX-Hhn2m, Hainantoxin-III-5, HNTX-III-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 15 (Hntx-3) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y523_RICBR
Sequence: MSELLTKKISAFIITKNEAARIERAINSVKNIADEVIVVDSESTDKTVIIAESLGAKVVVKPWLGYVGQKSFAETICKNDWILNIDADEELSKELQDEIEYIFASQNQDRYLAYQIKLLIMHRNDTRPRIFAPYNKCTRLYNKKFASFANTINSTTHDSVVFNKDVDFANKIYTLNEAAYHYSGTSIEQLVAKANFYSGEQAKDLIKQGKKPSNIRIATEMIWWFFKAFFIRRYFVFGFDGFVDSMIFAFARFLRLAKLRELSLQCNPATRSQDLKTQFVIQDPVDKPRDDNIV
What are the official names of this protein?
Uncharacterized glycosyltransferase RBE_0523.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfamily.
Protein: GLNE_AGRFC
Sequence: MTKRETVERRLSEVPPGVIRPYTQTELKSVFSTLKDIGKAEPAVAALLAGESPLKDFIAAAFTLSPYLRDMAAADEGLLTLAISKPLEPLLTDLVRDARDCWKPAEDAVPVENEVMSRLRIAKRRLSFVAALADLARIFTARDTTRWLSEMADASLSAAIDHLLLSAHESGKLKLKNLAAPSEGSGLIVLGMGKLGARELNYSSDIDAVVFFEPSAGIIDDPYDATENFGRMMRRLVRIMQERTADGYVFRTDLRLRPDPGSTPLAIPVEAALLYYEGRGQNWERAAYIKARPVAGDIKAGENFLRELTPFIFRKYLDYAAIADIHSIKRQIHAHKGHGAIAVKGHNVKLGRGGIREIEFFAQTQQLIAGGRMPPLRVRATEDALAALTEAKWIDAETRDSLTEAYWFLREVEHRIQMVRDEQTHVLPDTEAELKRIAFMLGFEDTKAFSEKLEEVLRLVERRYSALFEQETKLSGEAGNLVFTGQKDDPDTLKTLSTLGFQRPEDISRVIRTWHNGRYRATQSVEARERLTELTPDLLRAFGESKRADEALLRFDNFLSGLPAGIQLFSLLGNNPALLSLLVTIMSSAPRLAEIIAARPHVFDGMLDPALMSDVPTRDYLAHRMGNFLSNARHYEDILDRLRIFAAEQRFLIGVRLLTGAIRGEVAARAFTHLADLVIEAALNAVLSEMEAAHGPYPGGRVAVMGMGKLGSFELTAGSDVDLILLYDYDDTAQESTGAKPLDVVRYFTRVTQRLIAALSAPTAEGVLYEVDMRLRPSGNKGPVATRISAFEKYQREEAWTWEHMALSRARLICGDASLMEDARSIIASILSQKRDVAKVSTDVLDMRSLIEQEKPPENNWDFKLINGGLIDLEFIAQYLALIGPVKGLGAHEPGRNTAEALQALAAPVMESQAFDDCMAAMGLYTEISQIVRLCIDGAFNPKEAPAGLIDLVCRAGDCPDIPTLEGEVKRLSKAVRKAFVAVVKNGG
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: MNMA_STRZJ
Sequence: MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAITLGADYVATGHYARVVRDEDGTVHMLRGVDNGKDQTYFLSQLSQEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQPGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKALSKNILYVGQGFYHDSLMSTSLEASQVHFTCDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFAEPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_INCHY
Sequence: MSDKTVKSTNLMAFIATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKDGELLFNGTILQAESPTMTPASVEMKGKKLPIDFAPSNIAPIGQNPIYLSPCIPNFDGNVWEATMYHHRGATLTKTMNCNCFQRTIWCHPNPSRMRLSYAFVLYCRNTKKICGYLIARQVAGIETGIRKCFRCIKSGFVMATDEISLTILQSIKSGAQLDPYWGNETPDIDKTEAYMLSLREAGP
What is the function of this protein?
Prevents the establishment of the cellular antiviral state initiated by host RIGI, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7.  Participates also in the up-regulation of the splicing of viral mRNAs.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza C viruses NS1 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: BZPG_DICDI
Sequence: MLSVWNLPVEQQPQQQQQQQQNIINSSNNINSINSALDNILNTTSKGIQLPRFNLLNTSSSGFLTNSNDTLFLENNNNNNNNINQQLNKSVLNSSNKQLDIIKTINEISNEHKSFQPFEITPIKPQSTSTNTYNTEFGVINQNTFVLDSNKIEELRVDTSVLDPLLSLPYNIINNTTNNNNNNNNNNNNNNNNNNSNNNNSNNNNINNNNNKSNTPMKKESTIRNSNSTFEKFESPTLSTTFGLNKEELNTFTTTDMNNYVKQANMVKELSQVEKKELKRQKRLIKNRESAHLSRQRKRERLTDLEHRVEELSSNSIDINKTLSSLENENLILKAEVGQLFEVINDSPVLSALFYKIASLSQQPQKDTIGAY
What is the function of this protein?
Probable transcriptional regulator.
What are the official names of this protein?
Probable basic-leucine zipper transcription factor G.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRP3_SCHPO
Sequence: MAPSEKKLTEDKKNSSLNKKIETSNSSSEKSSENNNGDSQNNEAPKTFKELGVIDELCEACEKLGFKTPTPIQQEAIPVVLNKRDVIGLAQTGSGKTAAFALPVIQELWNNPSPFFAVVLAPTRELAYQISEQFEAIGGSIGVRSVVIVGGMDMVTQAVALSKKPHVLVCTPGRLMDHLENTKGFSLKNLKYLIMDEADRLLDMDFGPIIDKILKIIPHERRTLLFSATMTSKVEKLQRASLHQPVRVAVSSKFSTVDTLIQRYLFFPFKHKDTYLVYLVNELAGNSIIIFARTVNDTQRLAILLRTLGFSAIPLHGQLSQSNRLGALNKFKSGARSTLVATDVAARGLDIPLVDVVINYDIPTDSKAYIHRVGRTARAGRAGKSIALVTQYDLEPFLRIEATIGKKMQEYEIDKEGVFLLSERVGEAQREAIIQMKEIHDRRKSKGKLHTKRKRDDLDREEQIY
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase rrp3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1900_HISS2
Sequence: MNLQDHFLIAMPHLEDENFQRSVVYICENNEQGSMGLVLTQATDLSIAELCAKMNFMMADEREYSDKLVLLGGPVNLEHGFILHKKTAQEFQHSYKVTDQIYLTTSADIINTFGTAQSPEKYLVTLGCARWEPNQLENEIANNDWLVVPADENILFDVNSSERWFAANQLLGIEHVNFSYQQQMEHS
What are the official names of this protein?
UPF0301 protein HSM_1900.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: DBP8_KLULA
Sequence: MSNSEFKSLGCSKWLVEALNAMKIVQPTAIQKACIPEILKGRDCIGGANTGSGKTIAFAAPMLTKWSEDPQGMFGIVLTPTRELAMQIAEQFTAFGSAMNIRVAIVVGGESIVQQAIELQKRPHFIIATPGRLAHHVLNSGEDTIGGLKRVKFLVLDEADILLTETFSKDLATCVSILPPKNKRQNLLFTATMTDQVKALSDAPQTEGKPPVFTFEVESVDNVAIPKTLETTYLLVPEHVKESYLYQILTSEKYVKSSCIIFVNRTVTAEILRRTLKSLDVRVTSLHSQMPQQERTNSVQRFRAQAARVLIATDVASRGLDIPIVELVVNYDIPGNPDTFIHRAGRTARAGRHGESLCFVTEKDIQRVEAIEERINKKMEEFTDVGDTAVIRKSLTKVTAAKRESLMAMDKEGFGERRKLQKRKNESKEKTHRRT
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PCH18_PENRB
Sequence: MKGFLSLTLLPLLVAASPVAVNSIHNDAAPILSSMTSKDIPDSYIVVFKKHVDPSSASAHQSWLQEVHTAHTGRMELKKRSLFGFDFEAFMGLKHTFHIAGSLLGYAGHFHEDVIEQIRRHPDVDYIEKDSEVRTMSEGSVEKNAPWGLARISHRESLSFGNFNKYLYAEEGGEGVDAYVIDTGANVKHVDFEGRANWGKTIPQGDADEDGNGHGTHCSGTIAGKKFGVAKKANVYAVKVLRSNGSGTMSDVVKGVEWAAEAHIKKSKKGDKKFKGSVANMSLGGGSSRTLDLAVNAAVDAGIHFAVAAGNDNADACNYSPAAAEKAITVGASTLADERAYFSNYGKCTDIFAPGLNILSTWVGSDHATNTISGTSMASPHIAGLLAYYVSLAPAKDSAYAVADVTPKQLKAALISVATEGTLTDIPSDTPNLLAWNGGGSANYTKILADGGYKAHNAETTVEDRIGGIIDSAEKAFHKELGAIYSEIKDAVSA
What is the function of this protein?
Serine protease.
What are the official names of this protein?
Subtilisin-like serine protease Pen ch 18, Vacuolar serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: KCY_BURA4
Sequence: MKSTRPFHPTPVITIDGPTASGKGTVAALLAAHLGFHLLDSGALYRLAALASVRYGIAAEDIDALVKLIDDLHITFREGCAQLDGVDVSNDIRAEAVGNRASAIAVHGPVRSALVARQRAFRKTPGLVADGRDMGTVIFPDAVLKVFLTASAEARAARRHKQLMQKGFSANIDDLLRDLRERDARDSNRAAAPLKPAADARLLDTSALSVDEAVDQVLQWYRALGQPA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPH_XANC8
Sequence: MRFPRAVLFDLDGTLLDSAPDMLATVNAMLSERGLPCITLAQLRPVVSKGSRAMLAVAFAHLDAAAREALVPEFLKRYEALLGTQAQLFDGVEVMLQRLEQAGCVWGIVTNKPEYLAQLILPQLGWQQRCAVLIGGDTLAERKPHPLPLLVAADRIGVAATQCVYVGDDERDILAARAAGMPSVAALWGYRLGDDDPLSWQADVLVEQPPQLWEPAAWPQP
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: GSH1_PSEPK
Sequence: MSELLNRRLSLLGANLPLLKQCLHGIERECLRVTDEGRLAQTPHPEALGSALTNEQITTDYSESLLEFITPALADPAKVLESLEETHRFVYSKLGDEYLWSPSMPCTLPAEEDIPIAEYGSSNIGKLKHVYRKGLALRYGRTMQCIAGIHYNFSLPEALWPLLREAEGSTENDRDYQSSAYIALIRNFRRYSWLLMYLFGASPALDKGFLRGRPHQLEELDAETLFLPYATSLRMSDLGYQSNAQAGLTPCYNNLASYTDSLRKAVGTPYPPYVEIGTHVDGEWVQLNTNILQIENEYYSNIRPKRVTYTGERPIQALTSRGVQYVEVRCLDINPFLPVGIDLTEARFLDAFLLFCALEDSPQLDNGECGQCTSNFLTVVKEGRRPGLELHRNGQPISLKDWASELIGRIRQLANLLDQAQGSDEHAKALDAQQAKVDDTSLTPSAQVLARMTEHDESFVQFSLRQSRVHAETFREQPLSNEKQQAFETLARESLARQSELEQNEVGDFDLFVGAYQASILAISS
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: EF1A_TETPY
Sequence: MARGDKVHINLVVIGHVDSGKSTTTGHLIYKCGGIDKRVIEKFEKESAEQGKGSFKYAWVLDKLKAERERGITIDISLWKFETAKYHFTIIDAPGHRDFIKNMITGTSQADVAILMIASPQGEFEAGISKDGQTREHALLAFTLGVKQMIVCLNKMDEKTVNFSEERYQEIKKELSDYLKKVGYKPDTIPFIPISGFNGDNMLERSTNAPWYKGPILVEALDALEPPKRPVDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMSIQFAPNKVIAECKSVEMHHEQLPEAVPGDNVGFNIKGVSVKDIRRGNVASDAKNDPAKEAATFYSQVIIMNHPGQIQAGYTPVLDCHTAHIACKFETIHDKIDRRTGKSQEENPKFIKNGDAALVTLIPTKALCVEVFQEYPPLGRYAVRDMKQTVAVGVIKKVEKKDK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, 14 nm filament-associated protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CML48_ARATH
Sequence: MSYSNAYAPSAPELPESFVQQQHDGESRYTYAYPSYQPTQQFSSYSGMFSPETHPEIVRSFESADRNRSGFLEESELRQALSLSGYDGISNRTIRLLLFIYKIPVDSLLRLGPKEYVELWNCLAQWRAIFNRYDRDRSGKMNSTQLRDAFYNLGCVLPTSVHQLIVSQFDDGTGKTVDLCFDSFLECGMIVKGLTEKFRENDPGYTGYATLSYDVFMLMVIPFIATYD
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML48, Calmodulin-like protein 48.
Protein: VP10_CTFVL
Sequence: MLKRPAYYNIFLLPTGRRLAKTYNILENLITLPKTDWKLYETIEQKLKWMIQEYRSDWRDRLSHHERYGMKVRLTYRSESERTKLEEKITDLVISHGKKASTVHFCTRESYKGRVRANQILILLEPEGLGEVEGLTVRAEGNWMSLVTHCLFILGSTLTCFGFVDPARGCRFNLLPYIKTLHPNDKWLLDLQASWRLEYGVSRSIEEGALYDFFAESHTLYAVRTWPGCEKYLGALEAFVGRLAVLPAQVLTSKEHDFQSKLMSKAKKTGFHYLYYLVSFTMKTSLTDRIVKEALATVKVFSFVVGRDHLPAVGVYSGEDFSKQFLSMAVGTMDTPSRYAITIVSGMQVDVDVKSVTGIASFKDGTQHTIVDEILLQPARLVLLGRKGGGKSRLSKIFSELGYNVLDSDTYGKVLTLVADRGEDGLDDALKKFVRLTPDERKAVPSIFETEMDRLCEVFGSRGLRPYAQRCQQQAGRLHWELYAAFQEFYDRTIRVITPDKFRFAYFAELERGGFDDNGLTFSPELKTVVFVHSMPELFEAMGGCVAEIVPTHSTRLAILLRGQGLSVNAELHLHDFYVALNQNGARKVSLGWLVHALNELLKMR
What is the function of this protein?
Minor inner capsid component.  Displays NTPase and RNA 5'-triphosphatase (RTPase) activities.  May function as a cofactor of polymerase VP1.  Associates with microtubules and plays a role in the formation, structural organization and morphology of viral inclusions, where the assembly of cores and the replication of viral RNA occur (By similarity).
What are the official names of this protein?
Microtubule-associated protein VP10.
What are the subcellular locations of this protein?
Virion. Host cytoplasm, host cytoskeleton.
Protein: PHRA_BACSU
Sequence: MKSKWMSGLLLVAVGFSFTQVMVHAGETANTEGKTFHIAARNQT
What is the function of this protein?
Signaling molecule involved in the regulation of sporulation (PubMed:8643670, PubMed:9238025).  Secreted during production, but the mature peptide acts intracellularly, indicating that it needs to be imported into the cell to function (PubMed:9200610, PubMed:8643670, PubMed:9238025).  Inhibitor of the RapA phosphatase activity (PubMed:8643670, PubMed:9238025, PubMed:11923303, PubMed:22267516).  Does not act on RapB (PubMed:9238025).
What are the official names of this protein?
Phosphatase RapA inhibitor, Phosphatase regulator A.
What is the protein family that this protein belongs to?
Belongs to the Phr family.
Protein: SBCC_STAA2
Sequence: MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIFDAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNHRIYKVHRQGPYIKEGNTTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFLISNSREKQGILRTLFDSEKFEAIREILKEELKKEKAQIENRYQQIDLLWQEIESFDDDKIKGLLELATQQIDKLIENIPLLQARSKEILAFVNESKETAIKEYEIIEKKTLENNILKDNINQLNKNKIDFVQLKEQQPEIDEIEAKLKLLQDITNLLNYIENREKIETKIANSKKDISKTNNKILNLDCDKRNIDKEKKMLEENGDLIESKTSFIDKTRVLFNDINKYQQSYLNIECLITEGEQLGDELNNLIKGLEKVEDSIGNNESDYEKIIELNNAITNINNEINIIKENEKAKAELDKLLGSKQELENQINEETTIMKNLEIKLDHYDKSKLDLNDKESFISEIKSAVKIGDQCPICGNEIQDLGHHIDFDSIAKRQNEIKEIEANIHAIKSNIAVHNSEIKFVNEKISNINIKTQSDFSLEVLNKRLLENENALNNQRDLNKFIEQMKEEKDNLTLQIHNKQLRLNKNESELKLCRDLITEFETLSKYNNITNFEVDYKKYVQDVNQHQELSKEIEDKLMQLSQRKLIEQNNLNHYENQLETYNNDLELNEQSIEMEMSRLNLTDDNDINEIIAWRGEQEELEQKRDTYKKRYHEFEMEIARLESLTKDKELLDSDKLKDEYEQKKEKMNTLIDEYSAVHYQCQNNINKTQSIVSHINYLNQELKDQQEIFQLAEIVSGKNNKNLTLENFVLIYYLDQIIAQANLRLATMSDNRYQLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLSGGETFQSSLALALGLSEIVQQQSGGISLESIFIDEGFGTLDQETLETALDTLLNLKSTGRMVGIISHVSELKNRIPLVLEVKSDQYQSSTRFKRN
What is the function of this protein?
SbcCD cleaves DNA hairpin structures.  These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions.  The complex acts as a 3'->5' double strand exonuclease that can open hairpins.  It also has a 5' single-strand endonuclease activity (By similarity).
What are the official names of this protein?
Nuclease SbcCD subunit C.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SbcC subfamily.
Protein: 3MGH_CHESB
Sequence: MSLTAFFSRPSVVVAKDLIGANFFVGSAGGIIVETEAYDREEPASHSFRGPTARNRSMFGPPAHAYVYRSYGIHWCLNFVCLPGSGVLIRALEPTAGIELMQERRRTISLKQLCSGPGRVGEALGIDRSLDGRGLDQPPFRLDLSNAKACAISGTRIGITRAAELEWRFGLEGSIYVSRKF
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: Y1542_STREM
Sequence: MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYIDYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFSKAYVSIWYKRYLELKNR
What are the official names of this protein?
UPF0374 protein Sez_1542.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: BASL_ARATH
Sequence: MASQWTIPKLVTWRVRDWASCFLACKIPLDGDEDGANNNGNTTNNNNLTFKRIKRKIKSTKKKRSERKLSLSPPGTRHHHLHLRSSSVSPTTSGSQHRRLSWPQPPVSEESGFIVFCFDREDGGFDVVKEGKQEKKETESSSEKSPRTVNRKLIYGDQGVGGTEKNNSPETKGTEQDQNDNTSCQGTKDVSSDVTERTKEEEDIDASDKSSGSSHSDEGRGSFAFPILGVEWMGSPAKMPESDDLSPKKQKPVALGFQCCRF
What is the function of this protein?
Regulates asymmetric cell division (ACD), especially in stomatal-lineage cells, probably by modulating accumulation and subcellular polarization of POLAR and SPCH (PubMed:30429609, PubMed:25843888).  Mediates an attenuation of MAPK signaling upon polarization of POLAR and ASK7/BIN2 in stomatal lineage ground cells (SLGCs) undergoing ACD, and relieves BIN2 inhibition of SPCH in the nucleus (PubMed:30429609, PubMed:25843888).  When phosphorylated, functions as a scaffold and recruits the MAPKKK YODA, MPK3 and MPK6 to spatially reorganize the MAPK signaling pathway at the cortex of cells undergoing ACD (PubMed:25843888).  Cortical polarization leads to elevated nuclear MPK6 signaling and lowered SPCH abundance in one of the two daughter cells, thus differentiating the two daughter cells after ACD (PubMed:27746029).
What are the official names of this protein?
Protein BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cell cortex. Cell membrane; Peripheral membrane protein. Note=Dynamic and highly polarized subcellular localization at the cortical polarity in a phosphorylation status-dependent manner (PubMed:19523675, PubMed:21903812, PubMed:30429609, PubMed:25843888, PubMed:27746029, PubMed:27422992). Polarity is only exhibited by one daughter cell after an asymmetric cell division (PubMed:27746029). ASK7/BIN2-mediated nuclear exclusion (PubMed:30429609). First localized to the nucleus in asymmetric cell division (ACD) precursors (PubMed:30429609). In asymmetrically dividing stomatal-lineage cells, before division, accumulates in a polarized crescent at the cell periphery (e.g. meristemoid mother cells (MMCs)), and, after division, localizes differentially to the nucleus (e.g. in meristemoids) and a peripheral crescent in self-renewing cells and their sisters (e.g. stomatal lineage ground cell (SLGC)) (PubMed:19523675, PubMed:30429609, PubMed:25843888, PubMed:27422992). Localized in the cell periphery at a position that minimizes the inverse distance from all points along the new division boundaries (PubMed:21903812).
Protein: CCD39_DANRE
Sequence: MSSALLEEVGWDADFAIPVANAENKALEEQIRKKQKDILNLDNKLNKHKDVINALTEHLKNLKQEVSHNQALCKAKEKETESEVHLKALAERETGRLKQEITRLESQLTTLNEKKNAQENSIFKATQKIDELTSQLNWDQQTLEAFLQESAHKDEDTMAIIKYAKQDERKIKELTLNIEKLTLESNQKRKTLDNELTETVTSQIALDKTAESFRQAHTERQELISQWENTIEQMRKRDQDIQQCAMMLAELNQTIREKNDLIKERKDFLEREIENNKELERNIGTVERQAFRLRQQLQEEEKNQRRLQDEVEVLKGTVDRTATDVETSRSQLSSMKKDIQDKTTKVEEAQLHNAALEEKLRMVTEAVLNGEEQAAQMEQLLREQEQNIKEIDSQLLRQKELLFKKSQEVQALRDKEKNVTAEICATRTALSNLDSKLRKLDQNFLQQQMIISNQDFQIQMLERKTLHLQGKVNTEEKKALEKKVADLAASLEEKKKTAANLNKQLKKLQDDIRCIKKDTEKIGAEKTNLSTKIQEVELFIETSEKERKKSRLKKQDSMVEKGLLKMEVQRLRNLLYDRADGVLTLEKRRLQLQTAMKEREEEIRVHREMLNKQVKLTEQERQGLSAAVNEAMSKIDKQRKRYEVLSVSLAPPEGEEDKSQAYFIIKAAQEKEELQRKGDELDAKIRKTEKEIHALENTLQVVNNCNSTHRKALTKVTESSPAHQEKLKLEEQRRAAEEKYKYKRRQTQELQEDIESMSNTLEGLLQEEKVLNEGIERTQAHVLSLNKDILSQEEKINRAVKQCAKYTKEIRSGKQSTEKTFEERDIELRELRDFNKSINKMLLDAMEGNPELSSILQIHFTQAGLSLPSPSSTPSSRLSSKPSSARSSASLHRSSNLSASSSPRSQSVSSPQMKTVDLGLGLSVTSPRGSQPSSAGSSRSSSKCKSP
What is the function of this protein?
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella.  Probably acts together with ccdc40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella.  Not required for outer dynein arm complexes assembly.
What are the official names of this protein?
Coiled-coil domain-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the CCDC39 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: RL7_DICDI
Sequence: MSQKVATKTAPVPESILKKRATSQKKAVDVAKLGRAQQLRNSRLNSVYFKRAEKYVSEYHKTEREAIRLNRIAKNSGTFYVPPAAKVAFVIRIRGINGVSPKPRKVLKLLRLLQLNNGVFVKLNKASINMLKLVEPYVAYGFPNLKSIKELIYKRGHLKIDGQRIPLTSNDMVEKQLGKFGIICVEDIIHEITTCGKHFKQVNNSLWPFKLNCPRGGFNMKKTPFLQGGDAGNREHLINNLIHRMN
What is the function of this protein?
Binds to G-rich structures in 28S rRNA and in mRNAs.  Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).
What are the official names of this protein?
60S ribosomal protein L7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TTLL9_MOUSE
Sequence: MSRQKNQNSKGHGVSKGKEREQRTLIRFKTTLMNTLMDVLRHRPGWVEVKDEGEWDFYWCDVSWLRENFDHTYMDEHVRISHFRNHYELTRKNYMVKNLKRFRKYLERESGKTEAAKCDFFPKTFEMPCEYHLFVEEFRKNPGITWIMKPVARSQGKGIFLFRRLKDIMDWRKGTSGKKPTGVETQPARANMNPSGSHDTRSSDDQKDDLPVENYVAQRYVENPYLIGGRKFDLRVYVLVMSYIPLRAWLYRDGFARFSNTRFTLNSIDDHYVHLTNVAVQKTSPDYHLKKGCKWMLQRFRQYLASKHGPKAVETLFSDMDNIFIKSLQSVQKVIISDKHCFELYGYDILIDQDLKPWLLEVNASPSLTASSQEDYELKTCLLEDTLHVVDMEARLTGKEKRVGGFDLMWNDGPVSREDGPSDLSGMGNFVTNTHLGCVNDRKEQLRQLFRSLQAQRKAPS
What is the function of this protein?
Probable tubulin polyglutamylase that generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins (PubMed:27257088).  Similar to TTLL1, may acquire enzymatic activity only in complex with other proteins as it is most likely lacking domains important for autonomous activity (Probable).  Mediates tubulin polyglutamylation which induces establishment of microtubule heterogeneity in sperm flagella, thereby playing a role in normal motile flagella axoneme structure and sperm flagella beating pattern (PubMed:27257088).
What are the official names of this protein?
Probable tubulin polyglutamylase TTLL9, Tubulin--tyrosine ligase-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
Protein: NUOD_DELAS
Sequence: MAEIKNYSLNFGPQHPAAHGVLRLVLELDGEVVQRADPHIGLLHRATEKLAESKTYIQSLPYMDRLDYVSMMCNEHAYCLAIEKLLGIEVPIRAQYIRVMYSEITRIMNHLMWLGSSGNDAGSSTTLIYTFREREDLMDMYEAVSGARMHAAYFRPGGVYRDLPDTMPQYKASKVRNARSVEIMNRNRHGSLLDFIDDFTQRFPKCADEYETLLTDNRIWKQRNVDIGVVTAERAMNLGLTGPMLRASGVAWDMRKSQPYEVYDRMDFDVPVGKTGDCYDRYLVRVAEMRQSNRIIKQCVDWLRANPGPVIVDNHKIAPPPREGMKSNMEELIHHFKLFTEGFRVPEGEAYAAIEHPKGEFGIYIVSDGANKPYRLKIRPPGFANLSAMDELCRGHMLADAVMVLSTLDIVFGDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.