PharMolix/UniProtQA huggingface dataset:
Protein: GAL1_STRSY
Sequence: MNTEQLKQAFLDVFGQEADATFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDQVLRFYSANFEELGIIEVDLNNLVFDKADNWTNYAKGVLKFLKEAGHVIDTGMEVFVYGNIPNGSGLSSSASLELLIGIIAEELYGLELTRLDLVKIGKQTENHFIGVNSGIMDQFAIGMGADNRAIYLDTNSLEYELVPLDLGDHVIVIMNTNKRRELADSKYNERRAECEKAVEELNAVLNIQTLGELDEWTFDQYSYLIKDENRIKRARHAVLENQRTLQARKALEEGDLATFGRLVNASHVSLEHDYEVTGLELDTLAHTAWEQEGVLGARMTGAGFGGCGIAIVHKDKVEAFKENVGKTYTEVVGYAPSFYVAEIAGGSRVLSRK
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP09_NPVOP
Sequence: MNSWQKIRMAKQQQVRVARQHRAAKLGRLYKAKKLRAELCEKLQLQRVNNDAALAKAFEEEFVYPHFSFYLYTLN
What are the official names of this protein?
8.9 kDa basic protein.
Protein: YBEY_LACLM
Sequence: MYVELVDETGQVPSEIIEQTKEVLAFAAKKLDLKESTEMSVTFVDNARSHELNLQYRETDRPTDVISLEYKPDESEFFFDEDMELPEELLEEMDPFIGELFISIDKAAEQAADYGHSIEREYGWLAVHGFLHINGYDHYTPEEESEMFALQEEILTAYGLTR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBXN6_BOVIN
Sequence: MKKFFQEIKADIKFKSAGPGQKLTESVGEKAPKEKPSQPPVRQPRQGPTNEAQMAAAAALARLEQKQPRARGPTSQDSIRNQVRKELRAEAAVSGDPEAPGSNTAPEPKEEGSAHLAVPGVYFTCPLTGAILRKDQRDARIREAILMHFSTDPVAASIMKIHTFNKDRDRVKLGVDTIAKYLDNIHLHPEEEKYRKIKVQNKVFQERIHCLEGTHEFFEAIGFQKVLLPIPDQEGPEEFYVLSEAALAQPQSLEWHKEQLLSAEPVRATLARQRRVFRPSTLASQFDLPADFFNLTAEEIKREQRLRSEAVERLSVLRTKAMREREEQREMRKYTYTLLRVRLPDGCLLQGTFYARERVAALYGFVREALQNDWLPFELLASGGQKLSEDENLAFNECGLVPSALLTFSLDAAVLEDIRAAGTQPDTSILKPELLSAIEKL
What is the function of this protein?
May negatively regulate the ATPase activity of VCP, an ATP-driven segregase that associates with different cofactors to control a wide variety of cellular processes.  As a cofactor of VCP, it may play a role in the transport of CAV1 to lysosomes for degradation.  It may also play a role in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins.  Together with VCP and other cofactors, it may play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.
What are the official names of this protein?
UBX domain-containing protein 6, UBX domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Early endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Lysosome membrane; Peripheral membrane protein. Note=Localizes at the centrosome both in interphase and during mitosis. May be recruited to endosomal and lysosomal membranes as part of a ternary complex with CAV1 and VCP. Recruited to damaged lysosomes decorated with K48-linked ubiquitin chains.
Protein: MURD_BRUA2
Sequence: MIPITALKDKTVALFGLGGSGIATAKAIVAGGARIIAWDDNPDSVARAQSAGIATGDLRQADWSQFAVFVLSPGVPLTHPQPHWSVDLARAAGVEIIGDVELFVRERNHIAPDCPFIAITGTNGKSTTTALIAHIIKATGRDMQLGGNIGTAILTLEPPCADRFYVVECSSYQIDLAPSLNPTAGILLNLTPDHLDRHGSMENYAAIKERLVAASGTAIIGIDDAYCQAIADRLHGAGIRVVRISKEKHLDRGYFADGAKLLWAQDGEIDEIASLEGIGSLRGAHNAQNALAAIVACLSAGLSLEEIHAGLKSFPGLAHRMEQVGRRGKVLFVNDSKATNAEATAPALSSFPQNIYWIVGGVPKAGGINSLTAFFPRVAKAYLIGEAAAQFAATLGGAVPFEISDTLAAAVAHAAGDAGNDAAPEPVVLLSPACASFDQFQNFEKRGDAFRDAVLALPGVMPMRGGS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDLDH_IPSPI
Sequence: MMVKIQDSVYLVTGGGSGLGEATAKLLLTEGARVTIFSRNEYKNEFPHDQVLSVKGDVRSESDVKRALEATIQKFGKLDGVMHCAGVFQNGDELFNMDTQQPGDYTVLTDIVTTNLLGTFNVNRLAIPYFLTNQPDEEGQKGIIINCSSTSGHSPMSSAVAYSTSKAAIIGLSYALAKQLSTLGIRVMDIAPALCDTPMFRRAVGFNQDIANFRNLFPARLIQPIEYANAVKHIIETPMLNGSSYQLDGALRP
What is the function of this protein?
Catalyzes the oxidation of racemic ipsdienol and (4R)-(-)-ipsdienol to form ipsdienone (2-methyl-6-methylene-2,7-octadien-4-one), an intermediate in the biosynthesis of pheromonal ipsdienol in male pine engraver beetles.  In contrast, (4S)-(+)-ipsdienol is not a substrate.
What are the official names of this protein?
Ipsdienol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: YAEH_ECO45
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: DCTA_CUPNH
Sequence: MRKPFYKILYVQVLFAICVGILLGHYWPDTGVAMKPLGDGFIKLIKMIIGPIIFCTVVTGIAGMSDMKKVGRVGGKALLYFEVVSTFALLIGLGAAHLLKPGVGFNIDPATLDTKAIAQYVSKAHGQSTVEFLMHIIPDTVFSAFANGDILQILLVSLFFGAALAVLGERARIVVQLIEQVSKVFFHIVHVITKVAPIGAFGAMAFTIGKYGLGSLVPLLKLIGTFYFTAIIFVLVVLGTIARMTGFSIVRFISYIKEELLIVLGTSSSEAALPHMMEKLEKLGCSRSVVGLVVPTGYSFNLDGTNIYMTMAVIFIAQATGIELTLMQQLTILAVAMITSKGASGVTGSGFITLAATLAVVPTIPVAGMVLILGIDRFMSECRALTNIIGNGVATVVVSAWERELDRKRLASVLNGGSGDVADLADVGQGVR
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1780_STAS1
Sequence: MRIYVNEIKVTEDSINCYTEQSTEGLQEAGQMLVDSDNYSFAYILDDGQSYSYLIFVQETWSMLYENKGKKLIINDELELKQFENEFNYILDNIQGNSNYGKEFVSVVENTFELD
What are the official names of this protein?
UPF0738 protein SSP1780.
What is the protein family that this protein belongs to?
Belongs to the UPF0738 family.
Protein: CCB14_ARATH
Sequence: MASSRVSDLPHQRGIAGEIKPKNVAGHGRQNRKVLGDIGNLVTGRDVATGKDVAKKAKQPQQQTKAEVIVISPDENEKCKPHFSRRTHIRGTKTFTATLRARSKAASGLKDAVIDIDAVDANNELAAVEYVEDIFKFYRTVEEEGGIKDYIGSQPEINEKMRSILIDWLVDVHRKFELMPETLYLTINLVDRFLSLTMVHRRELQLLGLGAMLIACKYEEIWAPEVNDFVCISDNAYNRKQVLAMEKSILGQVEWYITVPTPYVFLARYVKAAVPCDAEMEKLVFYLAELGLMQYPIVVLNRPSMLAASAVYAARQILKKTPFWTETLKHHTGYSEDEIMEHAKMLMKLRDSASESKLIAVFKKYSVSENAEVALLPSLDDFSVSCA
What are the official names of this protein?
Cyclin-B1-4, G2/mitotic-specific cyclin-B1-4, CycB1;4.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: NPD_CLOPE
Sequence: MDDKINKLKEIIKNSNNIVFFGGAGVSTESGIPDFRSANGLFNEKLNITFTPEQLVSHSFFERYPEEFFNFYKAKLIYPNSKPNDAHIALAKLEEMGKLKAIVTQNIDGLHQMAGSKNVFELHGSVLRNYCVDCHTFYDEKFILESKGVPKCTKCGGIVKPDVVLYEEPLDDNVIRGAIDAISKADTLIIGGTSLVVYPAAGLINYYFRGKNLVLINKSSTQADSKADLVINDSIGKVLGKVID
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_DAUCA
Sequence: MTRSLKKNPFVANRLLRKIDNLNTKAEKEIIITWSRASTIIPTMIGHTIAIHNGKEHLPIYITDRMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: P5CR2_HUMAN
Sequence: MSVGFIGAGQLAYALARGFTAAGILSAHKIIASSPEMNLPTVSALRKMGVNLTRSNKETVKHSDVLFLAVKPHIIPFILDEIGADVQARHIVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVQEGATVYATGTHALVEDGQLLEQLMSSVGFCTEVEEDLIDAVTGLSGSGPAYAFMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTRELQSMADQEKISPAALKKTLLDRVKLESPTVSTLTPSSPGKLLTRSLALGGKKD
What is the function of this protein?
Housekeeping enzyme that catalyzes the last step in proline biosynthesis.  In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+).  Can utilize both NAD and NADP.  Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153).  Involved in cellular response to oxidative stress (PubMed:25865492).
What are the official names of this protein?
Pyrroline-5-carboxylate reductase 2, P5C reductase 2, P5CR 2.
What is the protein family that this protein belongs to?
Belongs to the pyrroline-5-carboxylate reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: RPOA1_FRATN
Sequence: MSNNNSKQEFVPNIQLKEDLGAFSYKVQLSPVEKGMAHILGNSIRRVLLSSLSGASIIKVNIANVLHEYSTLEDVKEDVVEIVSNLKKVAIKLDTAIDRLDLELSVNKSGVVSAGDFKTTQGVEIINKDQPIATLTNQRAFSLTATVSVGRNVGILSAIPTELERVGDIAVDADFNPIKRVAFEVFDNGDSETLEVFVKTNGTIEPLAAVTKALEYFCEQISVFVSLRVPSNGKTGDVLIDSNIDPILLKPIDDLELTVRSSNCLRAENIKYLGDLVQYSESQLMKIPNLGKKSLNEIKQILIDNNLSLGVQIDNFRELVEGK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha 1, RNAP subunit alpha 1, RNA polymerase subunit alpha 1, Transcriptase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: YL242_MIMIV
Sequence: MSDWCYLNSEEKDKLIDKLYKKLIKKGRVVCEVSDIRHRIYKRLEYNGHKFERKIIGYEPGVISLSREHNTELEWNLWKIAGWINSKRITKEELELACETHNMMYPKRKVKVSSIEEAFDGELSIGQIYYLIQDKWKKVVDKNPNPFDYCNLRDTIVKIKLVK
What are the official names of this protein?
Uncharacterized protein L242.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L242/L243 family.
Protein: HRCT1_HUMAN
Sequence: MLGLLGSTALVGWITGAAVAVLLLLLLLATCLFHGRQDCDVERNRTAAGGNRVRRAQPWPFRRRGHLGIFHHHRHPGHVSHVPNVGLHHHHHPRHTPHHLHHHHHPHRHHPRHAR
What are the official names of this protein?
Histidine-rich carboxyl terminus protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: S25K_SOYBN
Sequence: KVLVFFVATILVAWQCHAYDMFPLRMNTGYGARTPEVKCASWRLAVEAHNIFGFETIPEECVEATKEYIHGEQYRSDSKTVNQQAYFYARDLEVHPKDTFVFSIDGTVLSNIPYYKKHGYGVEKFNSTLYDEWVNKGNAPALPETLKNYNKLVSLGFKIIFLSGRTLDKQAVTEANLKKAGYHTWEKLILKDPQDPSTPNAVSYKTAAREKLIRQGYNIVGIIGDQWSDLLGGHRGESRTFKLPNPCTTFSSSFTSQQSSLLPIYLYVIRCVQIGALASLYVVSAVCQQVM
What is the function of this protein?
May function as somatic storage protein during early seedling development.
What are the official names of this protein?
Stem 31 kDa glycoprotein, Vegetative storage protein VSP25.
Protein: CH10_BORAP
Sequence: MKNIKPLADRVLIKIKEAESKTISGLYIPENAKEKTNIGTVIAIGSNKEEITVKVGDTVLYEKYAGAAVKIENKEHLILKAKEIVAIIEE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERB_RHIML
Sequence: MKLAPYILERLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQATSTEYDKDGNIIGYGLTLRETSYVFEIDDRRLYAWCALDTLIFPALIGRTARVSSHCAATGAPVSLTVSPSEIQAVEPAGMAVSLVLPQEAADVRQSFCCHVHFFASVPTAEDWASKHQGLEGLAIVSVHEAFGLGQEFNRHLLQTMSSRTP
What is the function of this protein?
Cleaves the carbon-mercury bond of organomercurials such as phenylmercuric acetate.  One product is Hg(2+), which is subsequently detoxified by the mercuric reductase.
What are the official names of this protein?
Alkylmercury lyase, Organomercurial lyase.
What is the protein family that this protein belongs to?
Belongs to the MerB family.
Protein: RL36_COLP3
Sequence: MKVRASVKKICRNCKVVKRKGVIRVLCVEPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GUAA_CLOAB
Sequence: MDKQLVLVIDFGGQYNQLIARRVREHNVYCEIVPYTYSIDKIKEKKPSAVIFTGGQNSVYGEDSPRMDKEIFDLGVPVLGICYGHQLITYTLGGEVMGSEIREYGKTDVTLDSVCELFEGIDIENSCWMSHTDRVAKVPEGFKVVGHTNVCPVAAMANTEKKIYGVQFHPEVLHTPFGEQLFSNFLFKICGLKEDWSMSSFAKEKIQEIKDIVGDKKVLCALSGGVDSSVAAVLVHKAIGKQLTCVFVDHGLLRKDEGDQVESIFRKQFDMNLIRVNAKDRFLGKLKGISDPERKRKIIGEEFIRVFEEEANKLGQIDFLVQGTIYPDVVESGTDTSATIKSHHNVGGLPEDMQFELIEPLRELFKDEVRAVGEELGIPHKLVWRQPFPGPGLGIRVLGEVTEEKLEIVREADAIFREEIANAGLEEKIWQYFACLPNIHSVGVMGDGRTYCETIALRAVTSSDAMTSDWARIPYEVLDKVSRRIVNEVKGVNRIVYDVTSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GCH1_XYLFA
Sequence: MDHSKQQNASITQAQAEEAVRTLLRWAGEDPTREGLLDTPRRVVEAYGDWFSGYREDPHDYLQRTFEEISGYDELIVLRNITYESHCEHHMAPIIGKVHIGYLPNGKVVGISKLARVVESYARRFQIQEKMTAQIAACIQETLTPRGVGVVIEGAHACMTTRGIHKRGVSMVTSKMLGTFREDARTRAEFLQFIEVGTNVMDL
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: TPIS_BARHE
Sequence: MSPNIRPFIAGNWKMNGTGESLGELRAIAAGISSDLGRLFEALICVPATLLSRAFDILGGENILLGGQNCHFDDYGPYTGDISAFMLKEAGASHVIIGHSERRTVYQESDAIVRAKVQAAWRAGLVALICVGETLEERKSNKVLDVLTRQLEGSLPDGATAENIIIAYEPVWAVGTGNTATSADVAEVHAFIHHKMHSRFGDEGAKIRLLYGGSVKPSNAFELLSTAHVNGALIGGASLKAIDFLTICDVYRKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_XYLFA
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGTIESFDQFVVLLRNTVSQMVYKHAISTVVPARNVRVGPGGGYVQSGSDTLQINDDEVE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: THO2_YEAST
Sequence: MAEQTLLSKLNALSQKVIPPASPSQASILTEEVIRNWPERSKTLCSDFTALESNDEKEDWLRTLFIELFDFINKNDENSPLKLSDVASFTNELVNHERQVSQASIVGKMFIAVSSTVPNINDLTTISLCKLIPSLHEELFKFSWISSKLLNKEQTTLLRHLLKKSKYELKKYNLLVENSVGYGQLVALLILAYYDPDNFSKVSAYLKEIYHIMGKYSLDSIRTLDVILNVSSQFITEGYKFFIALLRKSDSWPSSHVANNSNYSSLNEGGNMIAANIISFNLSQYNEEVDKENYERYMDMCCILLKNGFVNFYSIWDNVKPEMEFLQEYIQNLETELEEESTKGVENPLAMAAALSTENETDEDNALVVNDDVNMKDKISEETNADIESKGKQKTQQDILLFGKIKLLERLLIHGCVIPVIHVLKQYPKVLYVSESLSRYLGRVFEYLLNPLYTSMTSSGESKDMATALMITRIDNGILAHKPRLIHKYKTHEPFESLELNSSYVFYYSEWNSNLTPFASVNDLFENSHIYLSIIGPYLGRIPTLLSKISRIGVADIQKNHGSESLHVTIDKWIDYVRKFIFPATSLLQNNPIATSEVYELMKFFPFEKRYFIYNEMMTKLSQDILPLKVSFNKAEREAKSILKALSIDTIAKESRRFAKLISTNPLASLVPAVKQIENYDKVSELVVYTTKYFNDFAYDVLQFVLLLRLTYNRPAVQFDGVNQAMWVQRLSIFIAGLAKNCPNMDISNIITYILKTLHNGNIIAVSILKELIITVGGIRDLNEVNMKQLLMLNSGSPLKQYARHLIYDFRDDNSVISSRLTSFFTDQSAISEIILLLYTLNLKANTQNSHYKILSTRCDEMNTLLWSFIELIKHCLKGKAFEENVLPFVELNNRFHLSTPWTFHIWRDYLDNQLNSNENFSIDELIEGAEFSDVDLTKISKDLFTTFWRLSLYDIHFDKSLYDERKNALSGENTGHMSNRKKHLIQNQIKDILVTGISHQRAFKKTSEFISEKSNVWNKDCGEDQIKIFLQNCVVPRVLFSPSDALFSSFFIFMAFRTENLMSILNTCITSNILKTLLFCCTSSEAGNLGLFFTDVLKKLEKMRLNGDFNDQASRKLYEWHSVITEQVIDLLSEKNYMSIRNGIEFMKHVTSVFPVVKAHIQLVYTTLEENLINEEREDIKLPSSALIGHLKARLKDALELDEFCTLTEEEAEQKRIREMELEEIKNYETACQNEQKQVALRKQLELNKSQRLQNDPPKSVASGSAGLNSKDRYTYSRNEPVIPTKPSSSQWSYSKVTRHVDDINHYLATNHLQKAISLVENDDETRNLRKLSKQNMPIFDFRNSTLEIFERYFRTLIQNPQNPDFAEKIDSLKRYIKNISREPYPDTTSSYSEAAAPEYTKRSSRYSGNAGGKDGYGSSNYRGPSNDRSAPKNIKPISSYAHKRSELPTRPSKSKTYNDRSRALRPTGPDRGDGFDQRDNRLREEYKKNSSQRSQLRFPEKPFQEGKDSSKANPYQASSYKRDSPSENEEKPNKRFKKDETIRNKFQTQDYRNTRDSGAAHRANENQRYNGNRKSNTQALPQGPKGGNYVSRYQR
What is the function of this protein?
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export.  The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription.  THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase.  It functions in cotranscriptional formation of an export-competent messenger ribonucleoprotein particle (mRNP) by facilitating the loading of ATP-dependent RNA helicase SUB2 and the mRNA export factor YRA1 along the nascent mRNA.
What are the official names of this protein?
THO complex subunit 2, Low dye-binding protein 5, THO complex subunit RLR1, Zinc-regulated gene 13 protein.
What is the protein family that this protein belongs to?
Belongs to the THOC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYQ_SALA4
Sequence: MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGDIRYSSDYFDQLHAYAVELINKGLAYVDELTPEQIREYRGTLTAPGKNSPFRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIREDLNENAPRAMAVIDPVKLVIENYPQGESEMVTMPNHPNKPEMGSREVPFSGEIWIDRADFREEANKQYKRLVMGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHALPIEIRLYDRLFSVPNPGAAEDFLSVINPESLVIKQGYGEPSLKAAVAGKAFQFEREGYFCLDSRYATADKLVFNRTVGLRDTWAKAGE
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RADA_HELPY
Sequence: MAKKTSLFECQHCGFTSPKWLGKCVQCNAWESFIELNQAQKEVLNTLKKPIPQAQKSVSIAAIEHEEVIKFSSTQSELDIVLGGGIAKGGLYLVGGSPGVGKSTLLLKVASGLAKNQQKVLYVSGEESLSQIKMRAIRLDCIEKELYLLNEINWPVIKANIESENYFACVIDSIQTLYSPEISSAPGSISQVREITFELMRLAKTRDIAIFIIGHITKEGSIAGPRVLEHMVDSVLYFEGDPSRELRILRSFKNRFGPTSEIGLFEMKEQGLVSAKEASSLFFSKEEPMEGSAITITLEGSRALILEIQALVSECSFGSPKRLANGFDTNRLNMLIALLEKKLEIPLNRHDVFINVSGGIKISEPACDLAVIASILSSFKNRKIDNKTAFLGEVSLNGRILEAPNLNARLKEMENYGFLKAILPKKPSQKTSIKCYEANAVGKIVEWM
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function.
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: WRNXO_DROAN
Sequence: MDKYLIKLPNKNINDMVSDKKEVVKKETPKMTGRQAKKDTPKQEKEKENTQEDNTPKQNKAGRTGRSSIKRKNLDTPEVTQEKESVESENPPKRRSTRTTRSTRSMADGGTPSPEKEKPEKLPFIKYKGAIKYYTESQDIAASADDVMQWVEKQKEDVVPMAFDMEWPFSFQTGPGKSSVIQICVDEKCCYIYQLTNLKKLPSALVALINHPKVRLHGVNIKADFRKLQRDFPEVSADALIEKCVDLGVWCNVICQTGGRWSLERLANFICRKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRDLEQREKTKLANEEKFKEENGETAFKAVKALGEKFLSKMNEVTL
What is the function of this protein?
Has exonuclease activity on both single-stranded and duplex templates bearing overhangs, but not blunt ended duplex DNA, and cleaves in a 3'-5' direction.  Essential for the formation of DNA replication focal centers.  Has an important role in maintaining genome stability.
What are the official names of this protein?
3'-5' exonuclease, Werner Syndrome-like exonuclease.
What is the protein family that this protein belongs to?
Belongs to the WRNexo family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EIF3K_NEOFI
Sequence: MGVAFDKCDTRPAHIDAILNGLDRYNPETTTVFQDYVVQQCEERTFDCYANLALLKLYQFNPHLLQPETVTNILTKALTVFPSPAFSLCLALLPAHTQPFPTADTDASQSSDFVESIQKLARLSTLLESAQYAQFWSTLNSDDLYADLVADVAGFEELVRIRIAIEVGKAFREINAEVLEQWLDLRSREALEKFVTEVCSWEVDKAGPNGTVVKVPTNKENEARSEVKSERVGVEMFGRVIRRGFEQAA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YABDL_ORYSJ
Sequence: MDLVSPSEHLCYVRCTYCNTVLAVGVPCKRLMDTVTVKCGHCNNLSFLSPRPPMVQPLSPTDHPLGPFQGPCTDCRRNQPLPLVSPTSNEGSPRAPFVVKPPEKKHRLPSAYNRFMREEIQRIKAAKPDIPHREAFSMAAKNWAKCDPRCSSTVSTSNSNPEPRVVAAPIPHQERANEQVVESFDIFKQMERSG
What is the function of this protein?
Regulates carpel specification in flower development.  Severe or intermediate mutation in DL causes complete or partial homeotic conversion of carpels into stamens without affecting the identities of other floral organs.  Interacts antagonistically with class B genes and controls floral meristem determinacy.  Regulates midrib formation in leaves probably by inducing cell proliferation in the central region of the leaf.
What are the official names of this protein?
Protein DROOPING LEAF, Protein CRABS CLAW homolog, Protein CRC homolog.
What is the protein family that this protein belongs to?
Belongs to the YABBY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LGT_CORDI
Sequence: MGNIQYLAAIPSPPQGVWHLGPVPIRAYALCIIVGIFVAMKIGSVRYQQRGGNPDLVIDAGIVAVIAGIIGGRLYHVLTDNQKYFCADCNPVDVFKITNGGLGIWGAVALGTIAVYFYLKKKGVAFALFADAVAPGIILAQAIGRLGNWFNQELYGRETSVPWALEIYYRVDASGKFAPLTGHSTGEVMATVHPTFLYEMIWNLVIFAVLLWADKKFQLGHGRVFALYVAGYTAGRFVVENMRADDATMVFGLRINVIVSVVVCAIAVGALFALRRGRESISS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.