PharMolix/UniProtQA huggingface dataset:
Protein: FIXA_RHILP
Sequence: MHIVICIKQVPDSAQIRVDPVTNTIMRQGVPTIINPYDLFALEERSSCASHGGEVTVLTMGPPMAEDALRKALTVADRAVLLTERHFAGSDTLATSFALSRAIAKIGEAFGTPDIVFTAKQTIDGDTAQVGPGIAKRLDLLQLTYVAKIVSVDINGREITVERRSEGGTQTLMSKLPCLITMLEGTNEIRRGSLDDALRAARSQIVKWNAADAGIEDLTKCGLRGSPTVVKRVFAPPERAEKAEQIDTAEKTPRDLAEELIAGIFLRSGVESELAFDAN
What is the function of this protein?
May play a role in a redox process involved in nitrogen fixation.
What are the official names of this protein?
Protein FixA.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
Protein: END4_CLOBA
Sequence: MLNIGCHLSSSKGFKNMGENALKIGANTFQFFTRNPRGSKAKDIDENDVKEFLELAKENKFCKILAHAPYTLNACSADERNREFAIEIMADDLKRMEYIPNNLYNFHPGSHVKQGTEVGIEYISSALNSILKKDQTTKVLLETMSGKGTEVGRNFEEIAEIIKRVELKEHVGVCLDTCHIHDAGYDIVNELDEVLEEFDSMIGLDKLYAIHLNDSKNPFESHKDRHETIGNGYIGLDALTNIINHPKLCHLPFFLETPNELEGYKREIELLKSAYKK
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: CYPLA_PSYLE
Sequence: GLPICGETCFTGTCNTPGCSCTYPICTRD
What is the function of this protein?
Probably participates in a plant defense mechanism (Probable).  Has insecticidal activity against H. armigera larvae (PubMed:28006906).
What are the official names of this protein?
Cyclotide psyleio A.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebius subfamily.
Protein: GER3_WHEAT
Sequence: MGYSKNIASGMFAMLLLASAVLSSNPHPLQDFCVADLDGKAVSVNGHMCKPMSEAGDDFLFSSKLAKAGNTSTPNGSAVTDLNVAEWPGTNTLGVSMNRVDFAPGGTNPPHIHPRATEIGIVMKGELLVGILGSLDSGNKLYSRVVRAGETFLIPRGLMHFQFNVGKTEASMVVFFNSQSPSVVFVPLTLFGSNPPIPKPVLTKALRVEAGVVELLKSKFAGGS
What is the function of this protein?
Produces developmental and stress-related release of hydrogen peroxide in the apoplast.  May play an important role in several aspects of plant growth and defense mechanisms.
What are the official names of this protein?
Oxalate oxidase GF-3.8, Germin GF-3.8.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Cytoplasm. Secreted, cell wall. Note=Found in the apoplast and the cytoplasm of germinating embryo cells. Associated with the cell wall.
Protein: RIMM_ECO55
Sequence: MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLDGQVIKKVDLTTRSIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNY_ALKMQ
Sequence: MAKKIKDDADKNAETTKKEVLLEAKEEIHKLRNEFERESRERRNELQRVERRLMQKEESLDKKSETLEQKDDRLSRKLRDLETKEEEIKLLYNKEVQKLEELSGLTSQQARELLLSDVEKEVKYEAAMMVKDIETKAKDDADKKAREIITLAIQKCAADHVAETTVTVVQLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREVARIALEKLIADGRIHPARIEEMVEKAKKEVENILKEEGEQATFDTGVHGLHPELIRLLGRLKYRTSYGQNVLKHAIEVSHLAGLMATELGADPKLAKRAGLLHDIGKAVDHEVEGTHIEIGMELLRKYKETKDVIHAMSTHHGDFEPETIEAILVTAADAISAARPGARRETLESYIKRLEKLEDIANNYDGVEKSFAIQAGREIRIIVKPEVYNDDEIYMFAREITKKIEADLEYPGQIKVNVIRETRAIEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
Protein: LACC_STAAN
Sequence: MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVNIPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDELFNQIEVLEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: DEOC_RHOE4
Sequence: MSEAALTRSQVAAMVDHTLLKPEATAADVTALIDEARSLGVLAVCVSPSMLPIRADGLVTAAVVGFPSGKHHSLVKGAEARLAVDQGATEIDMVIDVGAAVAGDYSAVLADILTVREAMGESAILKVILETAALSDEAIVECCRAAVRAGANFVKTSTGFHPAGGATVEAVELMARTVGPGVGVKASGGIRTTQAALDMIAAGATRLGLSGTRAVLDGLTD
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_CARHZ
Sequence: MMGLYTNKRILVVGAGKSGRAAAAFLIKRGAKVVLTDKKMSLPVDEELKKLAEEGVELVLGGYPLVKDWELLVVSPGVPLTEEPIAYSLKEGIPVLGEIELAYKELKAPIIAVTGTNGKTTTTSWIGEVLKIAGFKTLIAGNIGYPLIEAVEEEWDAVSLEVSSFQLETIKSFKPKVAVLLNLTPDHLDRHKTLEGYLEAKARIFINQDRTDVTVLNYDDPRIRSLGRKTPGRVFYFSQKEELEEGVFVKKGKIVVRSLGVEEEIIDIENLPLPGPHNLENALATVAACWSFGVSGKNIERGLRNFQGVAHRLEKVAEINGVLYVNDSKGTNPDSTIKALNSYERPIVLIAGGRNKGNSFGELAREIREKVRFTILVGECREELKEALEMVGYDKYVVAESFEDAVKKAKELARPGDVVLLSPAAASWDMFKNYEERGELFKRLVLNMVEG
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_STRCO
Sequence: MAANSTPEGPLPVGEVSRLIGGWIDRLGAVWVEGQITQLSRRPGAGVVFLTLRDPSYDISVSVTCYRQVFDAVADVVGEGARVVVHAKPEWYAPRGQLSLRAAEIKPVGVGELLARLEQLKKALAREGLFAAERKQPLPFLPQLIGLVCGRASAAERDVLENARHRWPAVRFEVRNVPVQGVHAVPQVVQAVKELDARDDVDVIVVARGGGSVEDLLPFSDEQLVRAVAACRTPVVSAIGHEPDSPLLDLVADLRASTPTDAAKKVVPDVGEEYERVRLLRDRARRCVAAFVDREERGLAHALARPSIQDPHRMIEERAEQVTALLDRGRRSLRHHLDRADSELTHTHARVVALSPAATLKRGYAVLQRADGHAVRDPGEVEPGETLRARVSEGDFSVRVDA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_STAA2
Sequence: MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTFVDKQEIQEINRTYRDKDKVTDVISFALEEDEPEIDFSGLDIPRVLGDIIICTDVAQEQANNYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR2_BACHK
Sequence: MKNISLLGASGSIGTQTLDVLRSHPDQFRLVAFSVGKNIDYAVKVIQEFSPQIVSVQREEDVLKLQAVSGNTKIVYGNEGLLEVALHPDAEIVVNAVVGSVGLLPTLRAIEAKKTIGIANKETLVTAGHLVMEAARKHNVSLLPVDSEHSAIFQCLNGENEKRISRLIITASGGSFRDKTRDELHHVTVEDALRHPNWSMGSKITIDSATMMNKGLEVIEAHWLFGIPYEQIDVVLHKESIIHSMVEFEDRSVMAQLGSPDMRVPIQYALTYPDRLPLSDTKQLNLWEIGTLHFEKMNQERFRCLRFAYEAGKAGGSMPAVMNAANEVAVEAFLQKRIGFLTVEDLIEKAMNHHNVIARPSLEEILEIDAATRRFVMEQI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase 2, DXP reductoisomerase 2, 1-deoxyxylulose-5-phosphate reductoisomerase 2, 2-C-methyl-D-erythritol 4-phosphate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GPD1_YARLI
Sequence: MSALLRSSLRFKHMSAVNRLTQQLRLLTASAPLSAANTAGKAPFKVAVVGSGNWGTTVAKIVAENCTAHPELFEPEVRVWVREEKVNGKNLTDIFNAEHENVRYLPKIKLPHNLIAEPDLLKAVEGANIIVFNLPHQFLAGVCKQLKGHVNPKARAISCLKGLDVTPQGVYLLSDVIENETGLHCGVLSGANLATEIALEKYSETTVAYNRPKDFFGEGDVTNDVLKALFHRPYFHVRCVQDVAGVSIGGALKNVVALCAGFVEGKNWGDNAKAAIMRRGMLEMINFSKRFFPETDINTLTVESAGVADLITSCAGGRNFKVGRAFGKESGSGKTIQDVEKELLNGQSAQGVITCNEVHELLKNKNMQKDFPLFESTWGIIHGELKIDDLPEILYHAN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYN1_HUMIN
Sequence: MVSLKSVLAAATAVSSAIAAPFDFVPRDNSTALQARQVTPNAEGWHNGYFYSWWSDGGGQVQYTNLEGSRYQVRWRNTGNFVGGKGWNPGTGRTINYGGYFNPQGNGYLAVYGWTRNPLVEYYVIESYGTYNPGSQAQYKGTFYTDGDQYDIFVSTRYNQPSIDGTRTFQQYWSIRKNKRVGGSVNMQNHFNAWQQHGMPLGQHYYQVVATEGYQSSGESDIYVQTH
What are the official names of this protein?
Endo-1,4-beta-xylanase 1, Xylanase 1, 1,4-beta-D-xylan xylanohydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
Protein: ZIP8_ORYSJ
Sequence: MRTNTTATVLLAAAVALLLATAARGDGGDGGCGKEDAAAGRDRARARGLKIAAFFSILVCGALGCGLPSLGRHVPALRPDGDVFFLVKAFAAGVILATGFIHILPDAFDNLTDDCLPAGGPWKEFPFAGFGAMVGAIGTLVVDTLATGYFTRALSKKDAATAAAVADEEKQSAAATQQHNHHHNHHVVGDGGGGGEEHEGQVHVHTHATHGHAHGSSALVAAVGEDDKETTLRHRVISQVLELGIVVHSVIIGISLGASQNPETIKPLVVALSFHQMFEGMGLGGCIVQAKFKVRSIVTMVLFFCLTTPVGIAVGVGISSVYNESSPTALVVEGILNSVAAGILIYMALVDLLAEDFMNPRVQSKGKLQLGINLAMLAGAGLMSMLAKWA
What is the function of this protein?
Zinc transporter that may mediate zinc uptake from the rhizosphere and may be responsible for the translocation of zinc within the plant.
What are the official names of this protein?
Zinc transporter 8, ZRT/IRT-like protein 8, OsZIP8.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YWRJ_BACSU
Sequence: MKGLNQFLNTDVEVVISGDTRFVGTLIDIGQDIFVIFDGCNYLYIPLLHLHQINKAKIVTSTEKPFLINPEDPMIEAETQAFSYRNTLNKVKGQFIEVYVTGGRSIHGYVTNVLNDYIVFFSPVFKILFISMHHLKWFTPYSTEQTPYTLDNSQLPVVPSKVPLVRNFEEQIKKNIGELVIFDMGEVPEKVGLLKGVSNNIIELINASGEPVIWKLNHLKTMHLP
What are the official names of this protein?
Uncharacterized protein YwrJ.
Protein: IHFA_PSYA2
Sequence: MSTLTKSDMIEHLMSHLNLTRQEGRCLVENFFDELSESLIDGKEVKLSGFGNFELKDKNSRPGRNPKTGEPVAVSARRVVTFKTGQKFRQQVDERLFDQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: NCAP_VSIVC
Sequence: MSVTVKRIIDNTVIVPKLPANEDPVEYPADYFKKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKALDGVLPDGVSDASRTSADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMAQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDNKYTPDDNTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK
What is the function of this protein?
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA.  In contrast, when associated with RNA, it is termed N.  During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=The nucleocapsid is synthesized in the cytoplasm, and is subsequently transported via microtubules to the cell periphery.
Protein: SYD_STRZP
Sequence: MKRSMYAGRVREEHIGQEITLKGWVGRRRNLGGLIFIDLRDREGIMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIVLNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEFIDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKYDDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDIDKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADTLEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQEGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTVALKQLEELSLQVEEDETNKTN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2982_ORYSJ
Sequence: MDGAVRGQGCVGRLRSFNKTKKKNRNCSDDMRNGDDEEKKYSHHDMKNNLRNDANEEKRKSSDDMRDGDFEEKKKCSRHDMKKNLRNDANEEKRKSSDDMRDGDDEEKKCSRQDMKKNLRNDADEEKRKSSDDMRDGDDEEKKKRSRHDMKKNSRNDADEEKRKRKRKCSDDLKKSVVNDASKEATSHSDWRKNRKAGSDAEQRGKKLLNGDKKAKSRKVTTPFFEKMRKIKMQRTSNQNGEKNMKSDGDSYKKTVPLSVNKGKMEKDGTNKRTLSNTLVAKERKMRPSDSMEMKMKKKKRDASFVQPDERTAQTFSTKNKEKKRKAPSTPLKREQKERVASSDNKKETKKACIVAIGNEKKNCRDGKKKKRKAAFAFFKFVRDEFEELLFIPPAVAPSLKDLIDRHVYLEDSEGKCSKIRLSVVDGSLAFYEGWNSFVSEHCIKWGEFLLFEYTPESTFSVRVFGIDSCERLHFSVKSGGKGAVKKRKERHTLSDDLISHYNGQYQDSEDIHDGPNVSGESPRSKEPKITVDAEIGTRNLVAKSINAASETQDSERVESGIGYGSLGALGNKVRNLSNGECDTRSDSVFCIQEKTRRSEVIIISDEAYSTQVDEDTMKQTAPSEASEIHHVTINTQKDLERVVDGVCCESSVALNNKMGNLILGEPKNKNISPACSTEKTNGSEITPTTGVIPLTQENIDTVKLNTLSCFEEDRSTTRESELAAAIPTTSETHDSDKDLGQKHQRNSVQVNSIIAVDKYPNDSEMNISGNIFRIYEAPAGTRCLEKWKRGIVNGRAALDDIGQVRPEKTQKAGEKLVGNCGAMGESPVDLRIESDVTDTCLKPILNIPIEELSILDSVSISKCGRSRTEVNHLFNQKGATVQLQTKKEPLKPTGSSGNRKGDKIAVSVNRVFAHQSELQIPQQENGNFTSCVTPVALLPAKAELLDLDDHSLQFCIPSTIQKWLELPKSLPITCRQKGRYDRNVVILKDPMRRLWPVFYHDKPVFVGFTAGWKPFAAANNLQAGDVCKFVKEMDEDELAFQVYITRK
What are the official names of this protein?
B3 domain-containing protein Os02g0598200.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDC_MYCTU
Sequence: MTPQKSDACSDPVYTVGDYLLDRLAELGVSEIFGVPGDYNLQFLDHIVAHPTIRWVGSANELNAGYAADGYGRLRGMSAVVTTFGVGELSVTNAIAGSYAEHVPVVHIVGGPTKDAQGTRRALHHSLGDGDFEHFLRISREITCAQANLMPATAGREIDRVLSEVREQKRPGYILLSSDVARFPTEPPAAPLPRYPGGTSPRALSLFTKAAIELIADHQLTVLADLLVHRLQAVKELEALLAADVVPHATLMWGKSLLDESSPNFLGIYAGAASAERVRAAIEGAPVLVTAGVVFTDMVSGFFSQRIDPARTIDIGQYQSSVADQVFAPLEMSAALQALATILTGRGISSPPVVPPPAEPPPAMPARDEPLTQQMVWDRVCSALTPGNVVLADQGTSFYGMADHRLPQGVTFIGQPLWGSIGYTLPAAVGAAVAHPDRRTVLLIGDGAAQLTVQELGTFSREGLSPVIVVVNNDGYTVERAIHGETAPYNDIVSWNWTELPSALGVTNHLAFRAQTYGQLDDALTVAAARRDRMVLVEVVLPRLEIPRLLGQLVGSMAPQ
What is the function of this protein?
Decarboxylates branched-chain and aromatic alpha-keto acids to aldehydes.
What are the official names of this protein?
Alpha-keto-acid decarboxylase, KDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: PHLP2_DICDI
Sequence: MGLGKTEWEDIQIKYGNMEAPPKQLTEDELFDLIKEAAEMATEAEKNEKLENASLKDLKDMEDDEDEDVLEQLRKKRIQQMKVEAELNKFGELKEISEPSYKSEVTECKGVMVVVHLFKNGIPQCQLVNQHLTILAKKFKATKFVKIRSEEAIHNYPDKNLPTILVYFNGDIVGQIITLRATGGDATTVNDIEWQLKQAHAIKSDLQEDPRITLARKKSQKSRYSKADSDESDNSDSDD
What are the official names of this protein?
Phosducin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
Protein: DAPF_XANC8
Sequence: MSADVHTGRLRFTKMHGAGNDFVVLDLRNGTPPPDASLAARLADRHFGVGCDQILTIETPRSAEAVAAYRIWNSDGSHSQQCGNGARCVAAWLVREGTAQGDVFTIDSPFTAHRVERLDAGTYSVAMGVPQFEPTQIPLAGFAHARDEYALPVHGETVRFGAVSMGNPHAVVEVGRVDAAPVERVGALLQQNAAFPESVNVGFAQVVDPAHVRLRVYERGVGETLACGSGACAAAVVLMHRGRVERDVRVSLPGGELRIRWAGEQAQVVMSGPAVFVFDGEWNQ
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_ECOBW
Sequence: MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_ECOLI
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFEB_ECOUT
Sequence: MQYEDENGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGTLSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLTQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDKQTGAPLGMLHEHDVPDYASDPEGKVIALDSHIRLANPRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKPIGGGYFFALPGVKDANDYLGSALLRV
What is the function of this protein?
Involved in the recovery of exogenous heme iron.  Extracts iron from heme while preserving the protoporphyrin ring intact.
What are the official names of this protein?
Deferrochelatase, Peroxidase EfeB.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family. EfeB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y839_MYCTA
Sequence: MVRADRDRWDLATSVGATATMVAAQRALAADPRYALIDDPYAAPLVRAVGMDVYTRLVDWQIPVEGDSEFDPQRMATGMACRTRFFDQFFLDATHSGIGQFVILASGLDARAYRLAWPVGSIVYEVDMPEVIEFKTATLSDLGAEPATERRTVAVDLRDDWATALQTAGFDPKVPAAWSAEGLLVYLPVEAQDALFDNITALSAPGSRLAFEFVPDTAIFADERWRNYHNRMSELGFDIDLNELVYHGQRGHVLDYLTRDGWQTSALTVTQLYEANGFAYPDDELATAFADLTYSSATLMR
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MRA_0839.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: NRAM_I01A2
Sequence: MNPNQKIITIGSICMVIGIVSLMLQIGNIISIWVSHSIQTGNQHQAEPCNQSIITYENNTWVNQTYVNISNTNLLTEKAVASVTLAGNSSLCPISGWAVYSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRTLMSCPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFKIEKGKVVKSVELNAPNYHYEECSCYPDAGEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGVFGDNPRPNDGTGSCGPVSPNGAYGIKGFSFKYGNGVWIGRTKSTNSRSGFEMIWDPNGWTGTDSNFSVKQDIVAITDWSGYSGSFVQHPELTGVDCIRPCFWVELIRGRPKESTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.