PharMolix/UniProtQA huggingface dataset:
Protein: X_HBVD7
Sequence: MAARLCCQLDPARDVLCLRPVGAESRGRPFSGPFGTLSSPSPSAVSTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQFLPKVLYKRTLGLSVMSTTDLEAYFKDCLFKDWEELGEETRLMIFVLGGCRHKLVCAPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: IMPTB_XENTR
Sequence: MDKLEDHDDNNLQSQIEEIEALSSIYGEEWCVIDEAARVFCIRISETQQPKWTVCLQIILPPDYPSSAPPIYQINAAWLRGQDRMTLSNSLEEIYVENAGESILYLWVEKIREFLTEKSQHSDGPDTCKTVMTEEGGHDCDEDDLPDISVLKLSSQSEQIFSPASDDEELPLIKHGESITDRRSTFQPHLSAVENPKQVQRVLNKLYENKKIASATHNIYAYRIYCQEKNSVLQDCEDDGETAAGGRLLHLLQILDVRNVLVVVSRWYGGILLGPDRFKHINNCARTILIQEGYADSTEETSKAGGKSKKPKSKKTK
What is the function of this protein?
Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation.  Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis.  Plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
What are the official names of this protein?
Protein IMPACT-B, Imprinted and ancient gene protein homolog B.
What is the protein family that this protein belongs to?
Belongs to the IMPACT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_BURPS
Sequence: MAVQQNKKSPSKRGMHRSHDFLTTSPLAVEPSTGEVHLRHHISPNGYYRGKKVVKTKND
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: LKH1_SCHPO
Sequence: MHSLKRRRNHAPDWQDFYKNGVPQEVIVIEDSASPRLTPNLPPPFSVHQLQSFVPPQPPSSSSPSTTGTVAVPINGANAVYPSTNSVSLPQSYDPWLDANGVVPLPHDVASHPSYMVQSPTSYHACSNNQSPFPHSHHPPLHNPLPVSCQPVLRPPPVPQVPSHWYPVSLPSPNLPHQPISKPPVIPNLPKLQVHPNRLPHPIHNHPYSSPTSYPPPLCPATYCPSNPPQLAPATAIAPSSQSSQHKSVNYSVTPSSINNHTAVPLSPTLAVWLPMTQPTFQPPSANVYQPASNANQVITPVSISDYRPPKKRKRAAWPPYKKVDRVNVPVVHDTTAFDPSTFDDDDGHYKVVPNSKFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAIPKYREASLIELRVLQTIAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNNNYIPFPLKHIQMLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQKVLNSCEIRLIDFGSATFEDEYHSSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELFTGQALFQTHEDSEHLCMMEKILGPFDRNMISRSSRTSQRFFKSDGKVRYPLSNTPKKSINYLQSLQTLEQIFAVSSPEVALLLDLLKKVFVYDPKRRITAKEALWHPFFTQPISSNL
What is the function of this protein?
Protein kinase that may act as a negative regulator of filamentous growth and flocculation.  Appears to have a role in normal cell wall and septum formation and in cell separation.  May have antagonistic function in the regulation of beta-glucan distribution between the sites for cell wall and septum assembly.
What are the official names of this protein?
Dual specificity protein kinase lkh1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.
Protein: BTBD6_MOUSE
Sequence: MLLPLACLHGRVAQCLTSLLVLAEPFPRPRRGAKARGAAPTSAEPAPAVAKMAAELYPPASPSAATATDIANSNAAGAAESTKVGLCCPPCLAPAPLPPLPAPPLPDNNNPESPNWQSFHPTLRERNALMFNNELMADVHFIVGALGAARRVPAHKYVLAVGSSVFYAMFYGDLAEVKSEIHIPDVEPAAFLVLLKYMYSDEIDLEADTVLATLYAAKKYIVPALAKACVNFLETSLEAKNACVLLSQSRLFEEPELTQRCWEVIDAQAEMALRSEGFCEIDRQTLEIIVTREALNTKEAVVFEAVLNWAEAECKRQGLPVTPHNKRHVLGRALYLVRIPTMTLEEFANGAAQSDILTLEETHNIFLWYTAAKKPLLDFPLTKRKGLAPQRCHRFQSSAYRSNQWRYRGRCDSIQFAVDRRVFIAGLGLYGSSSGKAEYSVKIELKRLGMVLAQNLTKFVSDGSSNTFPVWFEHPVQVEQDTFYTASAVLDGSELSYFGQEGMTEVQCGKVAFQFQCSSDSTNGTGVQGGQIPELIFYA
What is the function of this protein?
Adapter protein for the cul3 E3 ubiquitin-protein ligase complex (By similarity).  Involved in late neuronal development and muscle formation (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing protein 6.
What are the subcellular locations of this protein?
Cytoplasm. Note=Found in punctated bodies in the cytoplasm.
Protein: PYRG_CERS4
Sequence: MARYVFITGGVVSSLGKGLASAALGALLQARGFSVRLRKLDPYLNVDPGTMSPFEHGEVFVTDDGAETDLDLGHYERFTGVSARKTDSVSSGRIYSNVLEKERRGDYLGKTIQVIPHVTNEIKDFLRVGEDEVDFMLCEIGGTVGDIEGLPFFEAIRQFAQDKPRGQCIFVHLTLLPYVSASGELKTKPTQHSVKELRSIGIAPDVLLLRSERAIPEKEREKIALFCNVRKEAVIAAYDLKTIYEAPLAYHREGLDQAVLDAFGISPAPKPNLDRWVDVMDRLENAEGEVRVAIVGKYTQLEDAYKSIAEALTHGGMANRTRVRAEWINAELFEREDPSPFLEGFHAILVPGGFGERGTEGKIRAAQYAREKAIPYLGICLGMQMAVIEAARNLAQVKDAGSEEFDHEVGKKRFTPVVYHLKEWIQGNHIVERKHDDDKGGTMRLGAYTAALTPGSRVSEIYHATEIEERHRHRYEVDVRYREALEGCGLTFSGMSPDGRLPEIVEIKDHPWFIGVQFHPELKSKPFAPHPLFADFVRAAVEVSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: YBEY_CHLPM
Sequence: MTIQLHNTTRRALPEAKLKKAVRLVLSEEGGKAVSIDAIYCGGRMMRRINREFLGHDYDTDTVTFPYSEGLVVEGEFYVSLDEVGRNAVRFKSGFEQELLRVTIHSVLHLLGYDDASPEERGRMRQKEDRYLRILGAGVSSTEERSQV
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY075_POSPM
Sequence: MALPPGVPFLIRVSLILAFAPVCVVIVANFIWRHTDVALPTWPVTLLSVASTPLTILVRVWYRQWKYQRAAARLGAIMPPRWVGKKLGNLDILKEMLQTMQSGYIADFAWKLFNNLGNTVQMNVLGGTAYLTCDPNIIKSVLATDFNNFEKGDLFKQEMASVLGTGVFNADGDMWKWHRAMTRPFFSRDRISHFELFDRRSEQAVAKMTERFHSGYAVDFQDLISRFTLDSATEFLFGSCVNSLHSPLPYPHNQHPTPFSHPSSKSLASNPSRAEAVASAFMRAQIVLAERVAMGAIWPLLEMRKSRTGEHMRIIDEYLDPILKDALRRKEDMANIGAGIHDDKESSDTDGETLLDHLVRLTSDPVVLHDEVLNILIAGRDTTAGTLTFVVYFLCMYPDVFNRLRAEVLEKVGPNARPTYADIKEMRYLRAVINETLRLYPVVPFNIRWSIHEGTLPNPDPNGKPFYLPPKTPVTYTVFAMHRRKEYWGPDADEFDPDRFLDDRVAKYLTKNPFIFLPFNAGPRICLGQQFAYNEMSFFLIKLMQHFSAMELAPEAAPPESLPPAEWAVTGWGRKRIERFWPKSHLTLYSNGGMWVKMVEADDFDKDDRDVGI
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use carbazole and 3,5,4'-trimethoxy-trans-stilbene as substrates for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 75.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PAND_NOCSJ
Sequence: MLRTMMKSKIHRATVTQADLHYVGSVTVDEDLLDAADLLPGELVHIVDIDNGARLETYTIAGERGSGVIGINGAAARLVHPGDLVILIAYGQMEDVEAKGFEPHVVFVDADNRVVSTGSDPADAPAGSGLLRGDRPAGR
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEBA_STENO
Sequence: MSTAAKQNRSTSRVSKKKTAAPKEGAAKKSDKGHKYEYVELAKASLTSAQPQHFYAVVIDATFPYKTNQERYICSLKIVDPTLYLKQQKGAGDASDYATLVLYAKRFEDLPIIHRAGDIIRVHRATLRLYNGQRQFNANVFYSSSWALFSTDKRSVTQEINNQDAVSDTTPFSFSSKHATIEKNEISILQNLRKWANQYFSSYSVISSDMYTALNKAQAQKGDFDVVAKILQVHELDEYTNELKLKDASGQVFYTLSLKLKFPHVRTGEVVRIRSATYDETSTQKKVLILSHYSNIITFIQSSKLAKELRAKIQDDHSVEVASLKKNVSLNAVVLTEVDKKHAALPSTSLQDLFHHADSDKELQAQDTFRTQFYVTKIEPSDVKEWVKGYDRKTKKSSSLKGASGKGDNIFQVQFLVKDASTQLNNNTYRVLLYTQDGLGANFFNVKADNLHKNADARKKLEDSAELLTKFNSYVDAVVERRNGFYLIKDTKLIY
What is the function of this protein?
May function as protective capping of the single-stranded telomeric overhang.  May also participate in telomere length regulation during DNA replication.  Binds specifically to the T4G4-containing extension on the 3'strand and protects this region of the telomere from nuclease digestion and chemical modification.
What are the official names of this protein?
Telomere-binding protein subunit alpha, TEBP alpha, Telomere-binding protein 56 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the telombin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: TRUA_SHESW
Sequence: MRIALGIEYDGSGYFGWQRQAEVDSVQGQLERALSIVANEPIGLFCAGRTDAGVHATGQVVHFDTNAIRNEGAWTLGVNANLPDNIAVRWVKEVDDSFHARFSATARRYRYVIYNHSFRPGILRHGVSHYHGNIDADKMHQAAQVLLGEQDFTSFRAVQCQSKTPFRNVHSVNVTRQGMYVIVDIAANAFLHHMVRNIVGSLLEIGLGNQPLTWMGDLLALKDRNQAAATAKPHGLYLVDVTYPEQYQLPKLALGPLFMLD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RIMM_BRUSU
Sequence: MPRPENPIQLAVIGAAHGTRGEVRVKTFTGDPLAIADYGLLYDEQGKAYEILEARVAKTVVIVRFKGVNDRNAAEALNGTELFIDRSQLPDEELDEDEFFQTDLIGLEAVDGDGKSYGVVSAIFDFGGGDLIELSEKGKRPMLIPFTEAAVPEIDFDKGIIKVEPHAAGLIADEHDNPPHESGKKPKKP
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKAM_MACFA
Sequence: MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDNIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEWSELLGDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRTRGSRLNIIIVAEGAIDRNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMEEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMSGIIKESYRNGRIFANTPDSGCVLGMRKRALLFQPVTELQGQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRKRSGEGAV
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, muscle type, ATP-PFK, PFK-M, 6-phosphofructokinase type A, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_YERPE
Sequence: MTSSNLIKQLQERGLVAQVTDEDALAERLAQGPISLYCGFDPTADSLHLGHLVPLLCLKRFQLAGHRPVALVGGATGMIGDPSFKASERKLNTEDTVNEWVEKIRHQVSPFLDFDCGENSAIAANNYDWFGGMNVLTFLRDIGKHFSVNQMINKEAVKQRLNRDDSGISFTEFSYNLLQAYDFACLNKNHGVALQIGGSDQWGNITSGIDLTRRLHQQQVYGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSLEEINALEEEDKNSGKAPRAQYVLAENVTGMVHGPEGLAAAKRITDSLFSGDLHDMTEADFAQLAQDGMPTVELNRDADLQQALVNAELVPSRGQARTMIGSNAVAINGEKQADPEYVFTDADRLFGRYTLLRRGKKHYCLISWL
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRX3A_MOUSE
Sequence: MSFTLHSVFFTLKVSIFLGSLVGLCLGLEFMGLPNQWARYLRWDASTRSDLSFQFKTNVSTGLLLYLDDGGVCDFLCLSLVDGRVQLRFSMDCAETTVLSNKQVNDSSWHFLMVSRDRVRTGLVIDGEGQSGELRPQRPYMDVVSDLFLGGVPADIRPSALTLDGVQSMPGFKGLMLDLKYGNSEPRLLGSQSVQLEAEGPCGERPCENGGICFLLDGHPTCDCSTTGYGGTLCSEDVSQGPGLSHLMMSEQAREENVATFRGSEYLCYDLSQNPIQSSSDEITLSFKTWQRNGLILHTGKSADYVNLALKDGAVSLVINLGSGAFEAIVEPVNGKFNDNAWHDVKVTRNLRQVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDIRLELSRLARIGDTKMKIYGEVVFKCENVATLDPINFETPEAYISLPKWNTKRMGSISFDFRTTEPNGLILFTHGKPQERKDVRSQKNTKVDFFAVELLDGNLYLLLDMGSGTIKVKATQKKANDGEWYHVDIQRDGRSGTISVNSRRTPFTASGESEILDLEGDMYLGGLPENRAGLILPTELWTAMLNYGYVGCIRDLFIDGRSKNIRQLAEMQNAAGVKSSCSRMSAKQCDSYPCKNNAVCKDGWNRFICDCTGTGYWGRTCEREASILSYDGSMYMKVIMPMVMHTEAEDVSFRFMSQRAYGLLVATTSRDSADTLRLELDGGRVKLMVNLDCIRINCNSSKGPETLYAGQKLNDNEWHTVRVVRRGKSLKLTVDDDVAEGTMVGDHTRLEFHNIETGIMTEKRYISVVPSSFIGHLQSLMFNGLLYIDLCKNGDIDYCELKARFGLRNIIADPVTFKTKSSYLTLATLQAYTSMHLFFQFKTTSADGFILFNSGDGNDFIAVELVKGYIHYVFDLGNGPNVIKGNSDRPLNDNQWHNVVITRDSSNTHSLKVDTKVVTQVINGAKNLDLKGDLYMAGLAQGMYSNLPKLVASRDGFQGCLASVDLNGRLPDLINDALHRSGQIERGCEGPSTTCQEDSCANQGVCMQQWEGFTCDCSMTSYSGNQCNDPGATYIFGKSGGLILYTWPANDRPSTRSDRLAVGFSTTVKDGILVRIDSAPGLGDFLQLHIEQGKIGVVFNIGTVDISIKEERTPVNDGKYHVVRFTRNGGNATLQVDNWPVNEHYPTGNTDNERLQMVKQKIPFKYNRPVEEWLQEKGRQLTIFNTQAQIAIGGKDKGRLFQGQLSGLYYDGLKVLNMAAENNPNIKINGSVRLVGEVPSVSGTTQTTSMPPEMSTTVMETTTTMATTTTRKNRSTASIQPTSDDLVSSAECSSDDEDFVECEPSTDKSLSTSIFEGGYKAHAPKWESKDFRPNKVSETSRTTTTSLSPELIRFTASSSSGMVPKLPAGKMNNRDLKPQPDIVLLPLPTAYELDSTKLKSPLITSPMFRNVPTANPTEPGIRRVPGASEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYQVDETRNYISNSAQSNGTLMKEKQASSKSGHKKQKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.  May mediate intracellular signaling (By similarity).
What are the official names of this protein?
Neurexin-3, Neurexin III-alpha, Neurexin-3-alpha.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ERS1_ARATH
Sequence: MESCDCFETHVNQDDLLVKYQYISDALIALAYFSIPLELIYFVQKSAFFPYKWVLMQFGAFIILCGATHFINLWMFFMHSKAVAIVMTIAKVSCAVVSCATALMLVHIIPDLLSVKNRELFLKKKADELDREMGLILTQEETGRHVRMLTHGIRRTLDRHTILRTTLVELGKTLCLEECALWMPSQSGLYLQLSHTLSHKIQVGSSVPINLPIINELFNSAQAMHIPHSCPLAKIGPPVGRYSPPEVVSVRVPLLHLSNFQGSDWSDLSGKGYAIMVLILPTDGARKWRDHELELVENVADQVAVALSHAAILEESMHARDQLMEQNFALDKARQEAEMAVHARNDFLAVMNHEMRTPMHAIISLSSLLLETELSPEQRVMIETILKSSNLVATLISDVLDLSRLEDGSLLLENEPFSLQAIFEEVISLIKPIASVKKLSTNLILSADLPTYAIGDEKRLMQTILNIMGNAVKFTKEGYISIIASIMKPESLQELPSPEFFPVLSDSHFYLCVQVKDTGCGIHTQDIPLLFTKFVQPRTGTQRNHSGGGLGLALCKRFVGLMGGYMWIESEGLEKGCTASFIIRLGICNGPSSSSGSMALHLAAKSQTRPWNW
What is the function of this protein?
Ethylene receptor related to bacterial two-component regulators.  Acts as a redundant negative regulator of ethylene signaling.
What are the official names of this protein?
Ethylene response sensor 1, AtERS1, Protein ERS1.
What is the protein family that this protein belongs to?
Belongs to the ethylene receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL17_ECOLC
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: LPXA_AGRRK
Sequence: MSSIAKSARIHKLAVVEDGAVIGENVVVGPFCHVGPKVVLHDSVQLLTHVVVTGRTTIGKGTKIFPMAVVGGDPQSVHHGGEETTLDIGENCTIREGVTINTGTADYGGKTVVGNNNLFLANSHVAHDCRVGNNVIMSNNVMLAGHVTVEDRAILGGGCAVHQFTRIGRQAFVGGLSAASYDVIPYGMLNGNPGVLSGLNIVGMTRAGIERSVIHRVRRAYKSIFEGEGSIRDNATAIREEYADCKEAMEILDFIAADSDRALSSPNRGKG
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_CORA7
Sequence: MAVKIKLQRMGKIRNAEYRVIVADARTRRSGKAIENIGIYQPKQEPSLIQIDSERAQYWLGVGAQPTEPVLALLKVTGDWQKFKGLPGAEGTLKVAEEKPSKLDLFNAALAEANNGPTIEAITEKKRKAKEEAEAKAAAEKAAEEAAAAEAAKAEEEAAKAEEADSAEESAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MSHC1_CORU7
Sequence: MHAWPDPSVPAVAGTPVPLKLFDTADQRVKEVDTTPDANGEVGMYVCGITPYDSTHLGHAATYLTFDLAQRQLLANGHKVHYVQNITDVDDPLFERAERDGVDWRELGTSQINLFRSDMEILSVIPPRDYIGAMESVDEVIAMVQQLLDAGAAYELDQGDIYASIDATEQFGYESNLDRATMEEYFAERGGDPDREGKRDPLDALVWRGHREGEPAWDSPFGPGRPGWHVECSAIATNRLGSHFAIQGGGSDLAFPHHEFSAAHAEAALKVERMAGHYVHAGMIALDGVKMSKSLGNLVFVHKLSEAGHDPSAIRLAVFAGHYREDRDFSDAILAEAEERLTRWREQLAGEVSEAEATEVVDKLRAILADDLNTPEALSLLDGAAGDCNQIIATALDGLLGVRI
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 1, L-Cys:GlcN-Ins ligase 1, Mycothiol ligase 1, MSH ligase 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: UBIA_ALISL
Sequence: MTLSKAKAFWQLTRMNRPIGSLLLLWPTLWALFLAADGIPDWHVLIVFILGVVFMRSAGCVINDFADRKVDGHVKRTANRPLPSGLVSSKEALILFSVLVTCSFILVLTMNTLTIMLSSIGVLLAIAYPFMKRITYLPQFVLGLAFSWAIPMAYAAESNQVPPEAWLLFVINAVWTIAYDTQYAMVDRDDDLNIGIKSTAILFGRFDKLMIGLLQLTVLTLLIALGIQLSLPSLYNWGVLAAAGCFVYQQWLIKGREREACFEAFLNNNYVGGFIFVAISASVLI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 1A_CMVIX
Sequence: MATSSFNINELVASHGDKGLLATALVDKTAHEQLEEQLQHQRRGRKVYIRNVLGVKDSEVIRNRYGGKYDLHLTQQEFAPHGLAGALRLCETLDCLDSFPSSGLRQDLVLDFGGSWVTHYLRGHNVHCCSPCLGIRDKMRHAERLMNMRKIILNDPQQFDGRQPDFCTHPAAECDVQAHFAISIHGGYDMGFRGLCEAMNAHGTTILKGTMMFDGAMMFDDQGVIPELNCQWRKIRSAFSETEDVTPLSGKLNSTVFSRVRKFKTMVAFDFINESTMSYVHDWENIRSFLTDQTYSYRGMTYGIERCVIHAGIMTYKIIGVPGMCPPELIRHCIWFPSIKDYVGLKIPASQDLVEWKTVRYLTSTLRETEEIAMRCYNDKKAWMEQFKVILGVLSAKSSTIVINGMSMQSGERIDINDYHYIGLAILLHTKMKYEQLGKMYDMWNASSISKWFAALTRPLRVFFSSVVHALFPTLRPREEKEFLIKLSTFVTFNEECSFDGGEEWDVISSAAYVATQAVTDGKVLAAQKAEKLAEKLAQPVIEVSDRPEAPSPTPDDPADVCGKEQEVSELDSLSAQTRSPITRVAERATAMLEYAAYEKQLHDTTVSNLKRIWNMAGGDDKRNSLEGNLKFVFDTYFTVDPMVNIHFSTGKWMRPVPEGIVYSVGFNEHGLGPKSDGELYIVNSECVVCNNESLSNVTRSLQAPTGTISQVDGVAGCGKTTAIKSIFEPSTDMVVTANKKSAQDVRMALFKSSDSKEACTFVRTADSVLLNECPTVSRVLVDEVVLLHFGQLCAVMSKLKAVRAICFGDSEQIAFSSRDASFDMRFSKIIPDETSDADTTFRSPQDVVPLVRLMATKALPRGTHSKYTKWVSQSKVKRSVTSRAISSVTLVDLDSSRFYITMTQADKASLISRAKEMNLPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDLFKQFSYCLVALTRHKVTFRYEHCGILNGDLIAECIARA
What is the function of this protein?
Involved in the virus replication.  Contains a helicase domain and a methyltransferase domain.  The methyltransferase domain is probably involved in viral RNA capping.  Involved in the formation of ER membrane spherular invaginations in which RNA replication complexes form (By similarity).
What are the official names of this protein?
Replication protein 1a.
What is the protein family that this protein belongs to?
Belongs to the bromoviridae replication protein 1a family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: MINY2_MOUSE
Sequence: MENSPDSPQPLELGVAAGRVSPPEGRRRGGREAEDGPAGRAVDSGGQGAAAAAARSSLGDPTSPSQLGCGAGSDLKDGASSSPAASEVPSRGQHKVTASPELAEAAAGRGSGPVGDTGTCRVEQAAEEPSSTGAPSSSCSEPSPPGDSPSLDSLESFSNLHSFPSSSEFNSEEGAETRVPEDVEEGAAGPPRAAPLCKEEEEDPAQVLAASKERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAILNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLEAKPKEISEIQRVNYEQNMSDAMAILHKLQTGLDVNVRFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVKAVGNCSYNQLVEKIISCKQSDNSQLVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFSTMTKYKGQLYLLVTDQGFLTEEKIVWESLHNVDGDGNFCDSEFHLRPPSDPETVYKGQQDQIDQDYLMALSLQQEQQSQEINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQEQAQAVVTTTTPSTQAQQGQPAQASPSSIKQPGNSERKRKEPREKDKEKEKEKNSCVIL
What is the function of this protein?
Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.  Can also bind to polyubiquitin chains of different linkage types, including 'Lys-6', 'Lys-11', 'Lys-29', 'Lys-33' and 'Lys-63'.  May play a regulatory role at the level of protein turnover.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase MINDY-2, Deubiquitinating enzyme MINDY-2, Protein FAM63B.
What is the protein family that this protein belongs to?
Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
Protein: RL36_DEHMB
Sequence: MKVRASVKTMCEKCKIVKRNGVVRNICTNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.