PharMolix/UniProtQA huggingface dataset:
Protein: SH24A_XENTR
Sequence: MLKQILADMYIDPELLAELSEEQKQILFFKMRQEQIRRWQEWEAKCDQNEDKKRNSRPRKACNKSVHWRFGTDQEVWVWVMGEHSSDKPYDQICDEIIAEQARREAEKEAEQLRKKQEVELSQLSTLRLHPHNNADLLKKNTDTKQMVNENVRIANQQIINDENQSIIEKPRTVEDILSAATSKNKYEVKQKKENILKEKENDRLQERTQEIYMNWKEAQEVKQKLEKEDKEWQESLRKSKLADERRRSVAKQARDDYKRLSMQGINRGKVADTAKTFGAVKRPPIPPKPKLPPSANNSSINRMDRRQGIRRLNSAINRENIIKWFKEEQLPLKAGWDKSGSYVEPWFHGIISRQESEQLLGSHGHGSFLLRVSEKIQGYVLSYCSEEGCAHFLIDASATSYSFLGVDQLQHTTLADLVEYHKTEPIPSLGRELLRFPCGQKKGVCDYSDLLE
What is the function of this protein?
Inhibits estrogen-induced cell proliferation.
What are the official names of this protein?
SH2 domain-containing protein 4A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_METJA
Sequence: MILEEVYEIIKQRIKEKPEGSYVAKLTTDDKKTAINKICEKIGEESTELILAAKDDKKDEIIYEAADLIFHTMVLLAYKNIEFEELLKEFERRKK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJM_MYCPN
Sequence: MAEAKRDYYEVLGLSRDADDNDIKKAFRKLAKKYHPDRNKAPDAAQIFAEINEANDVLSNPKKRANYDKYGHDGVDNEGGFAFQADVFDSFFEEIEKSGAFDNLSESNTKKKEKTKTKKKGWFWGKSKQEESTSDTTEYADVDAGLEDYPPQSDYPDDIPDVDARIEEVDQSAYADDIPDVDAGMDWEQNAEVANSASEIIPDVDAGLADEFNTSSAAPQASDWEAMIGNPEYGYFDAAGEWNWKGFFDEAGQWVWLEETEPSSVSNDETTTDSDAVTAATTVEETDQDSWTANSAPEPVDVETPVELQPETEPEPIITLSSEPVEAPASVVIEPTPEIEETTSAVEMDASVKADVSDEADATNEPTEQDTISEPEQETDAAALEEINHTTADLEPAEVSATNDLEQDVVEKVNFSEPESTVDTAATDPVVEQATETSTNGFKFFNFSSFVLSDQNPNPQTPTHHEEDAAAPEPTVDETSGESTAPEVTIAESTVELETAAEINNPATFVEEYLQPTKTTVVDKLDEPTVAKPTVSDSENSVAPEPEFVAGPEQTFSWKPAISETEEIPLTAVEPASETQTLIAEDVTSPVTPTATAIPAPSINAVPTAPVAETFEAAVDFLKEAAKIEAQLPLVPTVPEQIDGTDPSLLTQWDEYLEKTRKLFHKLFLTEQLPFIVKTDQFEIVDPNLDEHNVNLIYTEHVPQICFLNEQLKEIRYTRKLVDPQTQVTTTESITLEVQLSHKSQTEAIAIFKGFGHDYGSGCGDLKVVLKVIPSVFFQLQADGLHTAALVDPLVAYNGGLIDVFGPVNSFKVDIEGGIANNDLIEFNQLGVLRTKTKRGSLYVHLYYSSVAKKGTKTNCQVQQFFDLVHVEYKLLNYNLKQLHNYHSALTAQKKTLDRKSYQCLAVESH
What are the official names of this protein?
DnaJ-like protein MG200 homolog.
Protein: LPQI_MYCBP
Sequence: MAFPRTLAILAAAAALVVACSHGGTPTGSSTTSGASPATPVAVPVPRSCAEPAGIPALLSPRDKLAQLLVVGVRDAADAQAVVTNYHVGGILIGSDTDLTIFDGALAEIVAGGGPLPLAVSVDEEGGRLSRLRSLIGGTGPSARELAQTRTVQQVRDLARDRGRQMRKLGITIDFAPVVDVTDAPDDTVIGDRSFGSDPATVTAYAGAYAQGLRDAGVLPVLKHFPGHGRGSGDSHNGGVTTPPLDDLVGDDLVPYRTLVTQAPVGVMVGHLQVPGLTGSEPASLSKAAVNLLRTGTGYGAPPFDGPVFSDDLSGMAAISDRFGVSEAVLRTLQAGADIALWVTTKEVPAVLDRLEQALRAGELPMSAVDRSVVRVATMKGPNPGCGR
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptidoglycan fragments.  Acts as a regulator for GlcNAc-MurNAc levels by cleaving disaccharides and allowing the breakdown of MurNAc.
What are the official names of this protein?
Beta-hexosaminidase LpqI, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor; Periplasmic side.
Protein: PYRI_SALSV
Sequence: MTHDNKLQVEAIKCGTVIDHIPAQVGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLTDEQVNQLALYAPQATVNRIDNYDVVGKSRPSLPERINNVLVCPNSNCISHAEPVSSSFAVKKRANDIALKCKYCEKEFSHNVVLAN
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: NANE_LATSS
Sequence: MKNNFLDKVKDRLIISCQALADEPLHSSFIMARMARAAYEAGASAIRANSVVDVQAIMDTVELPVIGLDKVDYSDAPIYITPTIKEMRGIAATGAAVVACDVTGRPRPHGEQLATIVETMRTEYPDTLLMADTASLDDVKEANRLGFDIIGTTMYGYTPATEGCNIADNDFEYLKQVLAMSKAPVIAEGKIDSPEKAVTALKLGCHSVVVGSSITRPQLIAKTYIDAVNEL
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: RS2_CUPPJ
Sequence: MSVTMREMLEAGCHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMFQDALKYVRQLAANRGTIMFVGTKRQSREILAEEAGRAGMPYVDARWLGGMLTNFKTVKTSIKRLKDMEAAKEAGALDTMSKKEALMFEREMIKLEKSIGGIKEMGGIPDAIFVVDVGYHKIAVTEANKLGIPVIGVVDTNHSPEGIDYVIPGNDDSSKAVALYVRGVADAILEGRANAVQEVVEAARGGDDFVEVQEG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: CC085_HUMAN
Sequence: MAYKMLQVVLCSTLLIGALGAPFLLEDPANQFLRLKRHVNLQDYWDPDHSSDVWVNTLAKQARETWIALKTTAQYYLDMNTFTFDMSTAQ
What are the official names of this protein?
Uncharacterized protein C3orf85.
Protein: SP1_RARFA
Sequence: MKCKKPSALFSALALVGALGAASVLGAASANSASPVAAATVQASSGSAKTSVAATSKSQDGDVLAAIVRDLKITKTQAKKRIKLEEKARQLEPRLQKKLGKKFAGLWISKNGKKIVVGVTTKKAAKVVKKAGATPKIVKSNLTTLKKRATKISKNAPSDIKNVNSWWVDPATNKVVIEARSKKAAKAAATAAGLTAGTYEITVSDDVIVPVRDYWGGDALSGCTLAFPVYGGFLTAGHCAVEGKGHILKTEMTGGQIGTVEASQFGDGIDAAWAKNYGDWNGRGRVTHWNGGGGVDIKGSNEAAVGAHMCKSGRTTKWTCGYLLRKDVSVNYGNGHIVTLNETSACALGGDSGGAYVWNDQAQGITSGSNMDTNNCRSFYQPVNTVLNKWKLSLVTSTDVTTSYVQGYQNNCIDVPNSDFTDGKQLQVWNCNGTNAQKVSFHPDGTLRINGKCLDARWAWTHNGTEVQLMNCNGHIAQKFTLNGAGDLVNVHANKCVDVKDWGGQGGKLQLWECSGGANQKWWRR
What is the function of this protein?
Major serine protease exhibiting lytic activity toward living yeast cells.  Similar to elastase in its substrate specificity and has a lectin-like affinity for mannose.  Mannoproteins may be the native substrate for RPI.
What are the official names of this protein?
Serine protease 1, Serine protease I, RPI.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MDTA_ECO55
Sequence: MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSRSAAPGATKQAQQSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTIIAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQTQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPEEKATSREYAKKGARS
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ENV_AVISN
Sequence: MDCLTNLRSAEGKVDQASKILILLVAWWGFGTTAEGYPLQQLWELPCDCSGGYVSSIPTYYTYSLDCGGSTAYLTYGSGTGSWSWGGGFKQQWECVFKPKIIPSVQGQPGPCPSECLQIATQMHSTCYEKTQECTLLGKTYFTAILQKTKLGSYEDGPNKLIQASCTGTVGKPVCWDPVAPVYVSDGGGPTDMIREESVRERLEEIIRHSYPSVQYHPLALPRSRGVDLDPQTSDILEATHQVLNATNPKLAENCWLCMTLGTPIPAAIPTNGNVTLDGNCSLSLPFGCNPPGSIDVSCYAGEADNRTGIPVGYVHFTNCTSIQEVTNETSQMGNLTRLCPPPGHVFVCGNNMAYTALPNKWIGLCILASIVPDISIISGEEPIPLPSIEYTARRHKRAVQFIPLLVGLGISGATLAGGTGLGVSVHTYHKLSNQLIEDVQALSGTINDLQDQIDSLAEVVLQNRRGLDLLTAEQGGICLALQEKCCFYANKSGIVRDKIRKLQEDLIERKRALYDNPLWSGLNGFLPYLLPLLGPLFGLILFLTLGPCIMKTLTRIIHDKIQAVKS
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N- terminus of Gag (By similarity).
Protein: HDOX_BACC4
Sequence: MIIVTNTAKITKGNGHKLIERFNKVGKVETMPGFLGLEVLLTQNTVDYDEVTISTRWNAKEDFQGWTKSAAFKDAHSHQGGMPEYILDNKIAYYDVKVVRMPMAAAQ
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme-degrading monooxygenase, Heme oxygenase, Iron-regulated surface determinant, Iron-responsive surface determinant.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFLB_STAES
Sequence: MLETNNHTNAWQGFKTGRWNKNIDVREFIQLNYSLYEGDDEFLEGPTKATETLWDQVMQLSKEERERGGMWDMDTKVASTITSHDAGYLDKDLEKVVGVQTEKPFKRSMQPFGGIRMAKAACEAYGYELDPETEKIFTEYRKTHNQGVFDAYSREMLNCRKAGIITGLPDAYGRGRIIGDYRRVALYGVDFLMEQKLKDFNTMSTEMSEDVIRLREELTEQYRSLQDLKELGQKYGFDISRPATNFKEAVQWLYLAYLAAIKEQNGAAMSLGRTSTFLDIYAERDLQNGDITEQEVQEIIDHFIMKLRIVKFARTPEYNELFSGDPTWVTESIGGVGIDGRPMVTKNSFRFLHSLDNLGPAPEPNLTVLWSTRLPENFKIYCAKMSIKTSSIQYENDDLMRESYGDDYGIACCVSAMKIGKQMQFFGARANLAKALLYAINGGKDEKSGKQVGPSYEGIKSDVLDYDEVFERYEKMMDWLAGVYINSLNIIHYMHDKYSYERLEMALHDTEIIRTMATGIAGLSVAADSLSAIKYAQVKPIRNEEGLVTDFEIEGDFPKYGNNDSRVDEIAVDLVERFMTKLRSHKTYRNSEHTMSVLTITSNVVYGKKTGNTPDGRKAGEPFAPGANPMHGRDQKGALSSLSSVAKIPYDCCKDGISNTFSIVPKSLGKEEADQNKNLTSMLDGYAMQHGHHLNINVFNRETLIDAMEHPEEYPQLTIRVSGYAVNFIKLTREQQLDVISRTFHESM
What is the function of this protein?
Catalyzes the conversion of pyruvate to formate and acetyl-CoA.
What are the official names of this protein?
Formate acetyltransferase, Pyruvate formate-lyase.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_BIFLD
Sequence: MIGMLTGRVESVETDTALIDVGGVGYEVRMSATDLSRLHAGQDTRVFTYMNLSQDAITLHGFLDRDAKKTFLQLIKVSGIGPKVAQSLLSTLTPSQLAHAIADNDATALAKAPGLGKKGAQKIILELKGSIDLSQIEGASAQAATSKSPVDTGTEQVVEGLISLGWRQQDAQQAVAEACAENDIPTPLATDDVPRVLRLALALMDRGR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ZIP3_ARATH
Sequence: MKTKNVKLLFFFFSVSLLLIAVVNAAEGHSHGGPKCECSHEDDHENKAGARKYKIAAIPTVLIAGIIGVLFPLLGKVFPSLRPETCFFFVTKAFAAGVILATGFMHVLPEAYEMLNSPCLTSEAWEFPFTGFIAMIAAILTLSVDTFATSSFYKSHCKASKRVSDGETGESSVDSEKVQILRTRVIAQVLELGIIVHSVVIGISLGASQSPDAAKALFIALMFHQCFEGLGLGGCIAQGKFKCLSVTIMSTFFAITTPIGIVVGMGIANSYDESSPTALIVQGVLNAASAGILIYMSLVDLLAADFTHPKMQSNTGLQIMAHIALLLGAGLMSLLAKWA
What is the function of this protein?
Mediates zinc uptake from the rhizosphere.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter 3, ZRT/IRT-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF_TRIL1
Sequence: MLIQNDRRMQRILSGLAVAVAILVPVLALASGGGEHHPDSGAQLKDFGWRVVDFALLAGIMIWALKKANVKGSLAERQLQIEKNLREAREARETAEAKLKEYTEKLEKANQEVDTLRAAMLKEAEAEKQRIVAEAQAAAAKVTEQAAQAADQEVLKARTELRVEAARLAVELAGGKLGAAVQKADHDRFVQDYLGKVVQL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GRP_ALLMI
Sequence: APAPSGGGSAPLAKIYPRGSHWAVGHLM
What is the function of this protein?
Stimulates the release of gastrin and other gastrointestinal hormones.
What are the official names of this protein?
Gastrin-releasing peptide, GRP.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle lumen.
Protein: RFRNP_METTP
Sequence: MLRQRFVFDTTALTDSQAWESEGCTTLCEGMSAILHRVAQARLHLGISCYVPYPSVYNEIRDFVRNNNCDIAILGKIDTWLVKKTPDRYRVKIPSKIFYEYVDYMRSRINKGMNVSEEAIWEAVSRCLSISATGEGREQMREEIEREVVGSIIRKFREKYRAALRYGILDSAPDIDVLLLAKDLDAAVVSQDLGIQRWAEQLGLRFMEARAFPQMVREYMSFVPLHTEELEDRMV
What is the function of this protein?
RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.
What are the official names of this protein?
RNA-free ribonuclease P, RNA-free RNase P, Protein-only RNase P.
What is the protein family that this protein belongs to?
Belongs to the HARP family.
Protein: ISCS_AERHH
Sequence: MKLPIYLDYSATCPVDPRVAEKMMQCLTMDGLFGNPASRSHRFGWQAEEAVDLARNQVAELIGADPREIVFTSGATESNNLAIKGVAHFYAGKGKHIVTSKTEHKAVLDTCRQLEREGYEVTYLEPMPNGLFTLEQIEGALRDDTILVSIMHVNNEIGVVQNIAAIGELCRSRKILLHVDAVQSVGKIPVDVEALKVDLLSMSAHKVYGPKGIGALYVRRKPRVRLEAQMHGGGHERGMRSGTLPTHQIVGMGEAFRIAKEEMVSEGQRIMALRQRLWDGIKDIEAVYINGDLEQRVPGNLNVSFAYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSMGRFTTEEEIDYAIKLIRDSIGRLREMSPLWEMYKDGVDLNTVEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
What are the official names of this protein?
Cysteine desulfurase IscS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APCF_AGLNE
Sequence: MQDTITNILNKYDLTGKYLDNNALTQITTYLNTALQRLEVVEIIQSQSSKIIKEAAARMYSEQPELLRPGGNSYTTRKYAMCLRDIEYYLRYATYAIIAGNNDILNERVLDGLKDTYNSLNVPIAPTVRSIQIMEEIIHNEISKQDLKIIKKSIISEPFDHMIQNLSEQDI
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin subunit beta-18, Allophycocyanin subunit B18.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the core of the phycobilisome.
Protein: SMD2_BOVIN
Sequence: MSLLNKPKSEMTPEELQKREEEEFNTGPLSVLTQSVKNNTQVLINCRNNKKLLGRVKAFDRHCNMVLENVKEMWTEVPKSGKGKKKSKPVNKDRYISKMFLRGDSVIVVLRNPLIAGK
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D2, Sm-D2, snRNP core protein D2.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: NADE_LEIXX
Sequence: MRDLQARIIHELNVRATIDPAAEVVERVDFLVRYVRAAGASGFVLGVSGGQDSSLAGRLCQLAVERLAEQGVAAEFIAVRLPYAVQNDEDDAQLALSFIRPERTVAVNIQRGVEGVGNEYRDALGEDMTDFAKGNVKARVRMVAQYAIAGQRRLLVVGTDHAAEAVTGFYTKYGDGGADLLPLSGLSKRQGRALLQHLGAPARLYEKAPTADLLDQSPGQTDEANLGLRYSDIDDFLEGKDVAEKVAIAIEARYLATEHKRRVPASMFDDWWTGGGFGR
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: TRPF_SACS2
Sequence: MVKLKICGNATLSDIIEFSKLDVDYLGIITDVVSQRFVKSEFLTFVKRYVEKPIVNVKVNVQISEIERELLVSDYFQIHRVLDDSELELLKSYDFRKRIILYVPASFEYKKYLERAIDTVDMVLVDSVKKGVGVDYNVVSSFLKDYPYLGVGGKISIDNISNFIDLNPAWLDISSSIEIYPGKKDINMVKKIVEVVKYGSSSNK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: ZDHC2_HUMAN
Sequence: MAPSGPGSSARRRCRRVLYWIPVVFITLLLGWSYYAYAIQLCIVSMENTGEQVVCLMAYHLLFAMFVWSYWKTIFTLPMNPSKEFHLSYAEKDLLEREPRGEAHQEVLRRAAKDLPIYTRTMSGAIRYCDRCQLIKPDRCHHCSVCDKCILKMDHHCPWVNNCVGFSNYKFFLLFLAYSLLYCLFIAATDLQYFIKFWTNGLPDTQAKFHIMFLFFAAAMFSVSLSSLFGYHCWLVSKNKSTLEAFRSPVFRHGTDKNGFSLGFSKNMRQVFGDEKKYWLLPIFSSLGDGCSFPTCLVNQDPEQASTPAGLNSTAKNLENHQFPAKPLRESQSHLLTDSQSWTESSINPGKCKAGMSNPALTMENET
What is the function of this protein?
(Microbial infection) Promotes Chikungunya virus (CHIKV) replication by mediating viral nsp1 palmitoylation.
What are the official names of this protein?
Palmitoyltransferase ZDHHC2, Acyltransferase ZDHHC2, Reduced expression associated with metastasis protein, Ream, Reduced expression in cancer protein, Rec, Zinc finger DHHC domain-containing protein 2, DHHC-2, Zinc finger protein 372.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Postsynaptic density. Postsynaptic recycling endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Translocates to postsynaptic density when synaptic activity decreases.
Protein: MTNN_SHEWM
Sequence: MKVGIIGAMEPEVAHLIASMDNAESQTIAGIEFVAGTLDGKEVIVTRSGIGKVAASIATTLLIEKYTPDAVINTGSAGGFVDTLAIGDIVISSEVRHHDVDVTAFGYEIGQMAQQPAAFMPDEKLKAAANKAVASLGEVKAIEGLICTGDSFICDPVRTKTMLEHFPTMAACEMEGAAIAQVCHQFAVPFVVIRSLSDNANNDSPVDFDSYIVKAGHHSALMVMSLLKHL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: GATC_LARHH
Sequence: MALSSDDVVKIARLARLRVSEAERGAVQGQLNGIFDLIEAMRAVDTAGVEPMAHPQDAALRLRADAVTETDRRSAYQAVAPQVENGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MCSB_BACLD
Sequence: MSLQHFIQNALSNWMRQEGPESDIVLSSRIRLARNLDKVRFPTLFSNEEASAIIALFEEQFTGYEVPGIGKFELVKMDQVQPLEKRVLVEKHLISPHLTEASFGACLLSENEEVSIMLNEEDHIRIQCLFPGFQLSEALKAANQVDDWIEDRIDYAFSEQRGYLTSCPTNVGTGLRASVMMHLPALVLTRQINRIIPAINQLGLVVRGIYGEGSEALGNIFQISNQITLGKSEHDIVEDLNSVVAQLIEQERSARKALYQTSQIELEDRVYRSYGVLSNCRMIESKETARCLSDVRLGIDLGIIKGLSSNILNELMILTQPGFLQQYSGGALRPNERDIRRAALIRERLKLENNGNRQEDETI
What is the function of this protein?
Catalyzes the specific phosphorylation of arginine residues in a large number of proteins.  Is part of the bacterial stress response system.  Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
What are the official names of this protein?
Protein-arginine kinase.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.