PharMolix/UniProtQA huggingface dataset:
Protein: TAR1_KLULA
Sequence: MSDQMPFPFNNFTYFFTLFSKFFSSFHHCTCSLSVSRQYLALDGIYHPLRAAFPNNSTRRKHFTNNWDPRHTGFSPSMTSCSKEHRQGPATKLPSSNYNSDVEDARFQI
What is the function of this protein?
May be involved in mtDNA stability or mitochondrial gene expression regulation at the post-transcriptional level.
What are the official names of this protein?
Protein TAR1.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UBA4_SCLS1
Sequence: MDCAEEKAKSLRRQIADTEAELAQLKLQLLSLEEKDTNSKNLEAKTSASEKDDPVTHIENKWPMSLEEYKRYGRQMIVPDIGIKGQLRLKSASILLVGAGGLGCPAAAYIAGAGVGTIGIVDGDIVEESNLHRQILHSTDRVGVNKAGIVKDYDIVLDCTDHPTSRYLISDICVLLQKPLVSASALRTDGQLIVLNNPALPPGDLSGGSCYRCVFPKPPPPEAVTSCGDGGIIGPVVGVMGVLQALEAIKLIASGKLAAVGENDNTSPTPKMNPTTMLLFSTNGSTPFRNVRLKGRRSNCFACGEEAQLALEQMSSGSMDYVLFCGMTHPVKLLSDEERIEARDYDSIRKEKEHLLIDVREKVQFDICNIEGSYNIPFSSFQGSKGSSDHPLSTLTENLNPKTPIYVVCRLGNDSQIVTKKMKDLGLDQKGDRYIGDIKGGLRSWKEQVDGSWPEY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a.  Its N-terminus first activates urm1 and mocs2a as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards urm1 and mocs2a.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; nfs1 probably acting as a sulfur donor for thiocarboxylation reactions (By similarity).
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase uba4, Common component for nitrate reductase and xanthine dehydrogenase protein F, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YONX_BACSU
Sequence: MNAQLFNLESRLDELENEINTQYCELDTNLDALKSNRIELESQLEKFESSLTNRLQGSISNNCRNDLLNLGYTHSQVDCMSDEEVYAALDKIDEEIHNTDQDYSTGFEDLEKQIIEMKRDYFIDRKERGSGNFDEAWEGEILDLEFEYTVLCLEKGLEPLNYIITWEG
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YonX.
Protein: NTDO_CAEEL
Sequence: MQLVPTDDPDEKIGRTSNGMQNATLPIDGPVNTEPKDPAREQWSGKLDFLLSVVGFAVDLGNIWRFPYLCFKNGGGVFLIPYSIMVLLTGVPLFYMELCLGQYYRKGAITTWGRICPLFKGIGYCVILTAFYVDFFYNVILAWGLHYLYTSFSFNLPWASCNNSYNSPACYEPHWSEDGTAMCRSANQSVSAEKISAAEEYFYKGFLGLHEANAPNSHVIRSVTDLGNVRWDIALSLFVVYLICYFSMWKGIHTSGKVVWFTALFPYVVLGILFIRGVTLPGWQNGIEYYLRPNFEMLKRPSVWQDAATQVFFSLGPGFGVLMAYSSYNDFHNNVYVDALFTSFINCATSFLSGFVIFSVLGYMSCKSGKPIEAVAQEGPGLVFVVYPEALSTMPYAPFWSVLFFLMLMTLGLDSSFGGSEAIITGLSDEFPILKKNREVFVGCLFAFYMVIGIAMCTEGGILIMEWLIIYGTTWGLLIAVFCEAMVIAYIYGLRQFVHDVKEMMGFRPGNYWKFCWSCAAPFILLSMITSNFINYQALTYQDYTYPTAANVIGIIFALSGASFIPLVGIYKFVNARGNTISEKWQRVTMPYRKRPNQTEYIPIPTTQPHSDIML
What is the function of this protein?
Dopamine transporter (PubMed:9765501, PubMed:29346382).  Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
What are the official names of this protein?
Sodium-dependent dopamine transporter, DA transporter, DAT.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCH1_BACC0
Sequence: MAKVNLEQIEHAVRLILEAIGDDPNREGVLDTPKRVAKMYAEVFSGMHEDPKEHLHKVFGEDHEELVLVKDIPFYSMCEHHLVPFYGVAHVAYIPQGGKVTGLSKLARTVDTIARRPQLQERITSTVANSIMEVLEPHGVMVVVEAEHMCMTMRGVKKPGAKTVTTAVRGVLENDAAARSEILSFIKTK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: STX2_SCOAN
Sequence: ALPSFSRADRYGXRQ
What are the official names of this protein?
Scolopendra 4722.07 Da toxin.
What is the protein family that this protein belongs to?
Belongs to the scolopendra toxin 2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IAN2_ARATH
Sequence: MGTSVSKPVSDDKKKGTSVSKPVKNIVLVGRSVNGICTTGNNILGQNKFGSEGAFMHCQMYSTTTPDGQMINVIKTPGMFDLSVSEDYISKEIINCLTLAEEGVHAVLFVLSMKNRITQEEEYALNTLQRIFGSKILEYLIFLLIDGEKFEAKEFEDYFPECCPEFLMRVLRFCNGRKVLFNNMTNDEGVKAEQVNQVMAHVAAISKKNDEKPYTEDMYRNIKVNTFFSLIAFI
What are the official names of this protein?
Immune-associated nucleotide-binding protein 2, AtIAN2, AIG1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
Protein: RL11_PARDP
Sequence: MAKKVVGSLKLQIKAGQANPSPPVGPALGQRGINIMEFCKAFNAKTQEMEQGAPVPVVITYYADKSFTFETKTPPASFLLKKAAGLKPQGKRNRAKGSEKPGRQTAGTVTAKQVREIAEAKMKDLSANDVEAAMQIILGSARSIGIEVKG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RNFC_YERPG
Sequence: MFKLFTARQHDKIWDFDGGIHPPEMKLQSSTVPMRIAPLPDQLIIPLQQHLGPEGELRVRAGEQVLKGQPLTVGRGRTVPVHAPTSGMITAIAPHTTAHPSGLAELCVHITPDGEDRWREQQPWADYRQRDKMALLDRIHQAGIAGLGGAGFPTASKLQGGLNGIITLIINAAECEPYITADDRLMQEHADEVITGIHILRHLLQPQQVLIGIEDNKPEAIAALQRALRGQDDIHLRVVPTKYPSGGAKQLTKILTGKEVPFGKHSSSIGVLMQNVGTVVAIKRAVIDDEPLIERVVTLTGDALSSPGNFWARIGTPVLYLLKLAGFKPQNPPMVIMGGPLMGFTLPSLDVPIVKISNCILAPAETEMGLSEPEQSCIRCGLCVDACPAGLLPQQLYWFSRGEEHEKARNHNLFDCIECGACAYVCPSNIPLVQYYRQEKAEIRALDQESARAAEAKARFEAKQARLAREKLARELRHKQAAVKLTDADQQTVDAAVSRLTRQSDGSESVINIPAGQMPDNSAVIAAREARKAQARARQAEKQQARSTEETTDVVDPRQAAVAAAIARVKAKKAVQAQHVTTDVAEAGSEAMAEDPRKAAVAAAIARVKAKKAAQAQHVTTDVAEAGSEAMAEDPRKVAVAAAIARVKAKKAAQAINPD
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HISX_VIBVY
Sequence: MRTVVWQSLSETQQDAILERPAITEGANITAAVAEVIAKVRAEGDAALFELTEKFDRIKPESIRVTEQEIEEASARLTAKMKQALEQAYANIAKFHNAQKPTPIKVETQPGVVCEQVTRPIQKVGLYIPGGSAPLPSTVLMLGVPAQIAGCRKVVLCSPPPIADEILYVAKLCNIDEVYNVGGGQAVAAMAYGTESVTKVDKIFGPGNAYVTEAKRQVSNDFRGAAIDMPAGPSEVLVIADETADADFIAADLLSQAEHGPDSQVVLVTPSVLIADQVTDAVQKQLKQLSRASIAEKALASSLIIIADSLTQAVSISNYYGPEHLIVQTKNPRELLPLLDNAGSIFLGDWSPESAGDYASGTNHVLPTYGYTRTYSSLGLADFSKRMTVQELSAEGLKNLAPTVVTMAEAEGLDAHKRAVTIRVEKLTARS
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: GGGPS_THEGJ
Sequence: MLEIGKVERYIHEKLKKEKLHFVLLDPDDVSPETAGKIAEMSEAIGVDAIMVGGSTGAEGEVLDSVVRAIKESSSLPVILFPGSHGGISRYADAIFFMSLLNSRNPFFITGSQALGAFTVKRYGIEPIPMAYLIIEPGETVGWVGDAKPIPRHKPKIAAAYALAGQYLGMRLVYLEAGSGAPQPVPPEMIALVRKVIDVPLIVGGGIRTKEQARRAVEAGADIIVTGTAVEKAGSIEKARKKLEELNSGVKI
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_STRU0
Sequence: MLDLKRIRTDFETVAQKLATRGVSEDSLNHLKELDEKRRQLLVSSEELKAERNLSSAAIAQAKRNKEDASQQIAEMQKMSADIKAIDAELAEIDEKVTEIITVLPNTPHDSVPVGADEDDNVEIRRWGTPREFDFEIKAHWDLGEDLDILDWERGAKVTGARFLFYKNLGARLERALYNFMLDEHAKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELKDSNFVLIPTAEVPLTNYYRGEILDGKDLPINFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVLALCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEVLRPYMGGAEMISPK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHJ_SYNE7
Sequence: MPEELTPTPETAVVEAGPVSRWLSENGFENTALERDHLGVEIVQVDREVLLPIAAALFAYGFNYLQCQGGYDLGPGQDLVSFYHLTKVSDDASQPQEVRVKVFLPRHDPKVPSVFWIWKGADWQERETFDMYGIQFEGHPNLKRILMPEDWVGWPLRKDYISPDFYELQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MOBA_STAAB
Sequence: MKAIILAGGHSVRFGKTKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KYNB_BURCH
Sequence: MDTLWDISPPVSPATPVWPGDTPVAVERVWRMEAGSPVNVARLTLSPHTGAHCDAPLHYDADGAPIGAVPLDTYLGPCRVIHCIGASPVVRPADVEAALDGVPPRVLLRTYARAAVEQWDSNFCAVAPDTVDLLAAHGVKLIGIDTPSLDPQESKTMDAHHRVRAHRMAILEGIVLDDVPPGDYELIALPLKFATLDASPVRAVLRALPAHAS
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: DAPF_MYCBP
Sequence: MIFAKGHGTQNDFVLLPDVDAELVLTAARVAALCDRRKGLGADGVLRVTTAGAAQAVGVLDSLPEGVRVTDWYMDYRNADGSAAQMCGNGVRVFAHYLRASGLEVRDEFVVGSLAGPRPVTCHHVEAAYADVSVDMGKANRLGAGEAVVGGRRFHGLAVDVGNPHLACVDSQLTVDGLAALDVGAPVSFDGAQFPDGVNVEVLTAPVDGAVWMRVHERGVGETRSCGTGTVAAAVAALAAVGSPTGTLTVHVPGGEVVVTVTDATSFLRGPSVLVARGDLADDWWNAMG
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_YERPP
Sequence: MLKKILPVLITLAIVHNTPTAWAAEAPKTDSFYLPKSLDLSPLRLHNIESNPYGKDFNYAQQFKTLDLEAVKKDIKTVLTTSQDWWPADYGNYGPFFIRMAWHGAGTYRIYDGRGGADGGQQRFEPLNSWPDNANLDKARRLLWPIKKKYGAKISWGDLMVLTGNVALESMGFKTLGFAGGREDDWQSDLVYWGAGNKMLSDNRDKNGKLPKPLAATQMGLIYVNPEGPNGKPDPVAAAKDIREAFARMAMNDEETVALIAGGHTFGKAHGAASPEKCLGAAPGEAGLEQQGLGWANKCGSGNGKDTITSGLEGAWTTDPTHFTMQYLSNLYKHEWVLTKSPAGAWQWKPKNAANVVPDATDPTKFHPLMMFTTDIALKVDPEYKKITTRFLENPEEFKMAFARAWFKLTHRDMGPAARYLGDEVPKETFIWQDPLPAANYKMIDSADISELKDKILKTGLSDTKLIKTAWASASTFRGTDFRGGDNGARIRLAPQKDWPVNDPAELHSVLAALMEVQNNFNKDRSDGKKVSLSDLIVLGGNAAIEDAAKKAGYSISIPFTPGRTDASQEETDVSSFAVLEPTADGFRNYYDAKRNTLSPIASLIDRANKLELTVPEMTVLIGGLRVLDVNSGGSKAGVLTNTPGQLNNNFFVNLLDMSTKWTKSPKAEGYFDGYDRKTGKLKWTASSVDLVFGSNPELRAVAEVYASDDAKEKFVHDFTKVWEKVMNLDRFDIKNN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: Y851_PROMH
Sequence: MDNASKPSFQNVLEFVRMYRRKNKIRREITDNEKKIRDNQKRVLLLDNLSEYIKPGMSIEDVLGIIANMRSDYEDRVDDYIIKNADLSKERRELSKQLKAMGEIKNIPNIKN
What are the official names of this protein?
UPF0265 protein PMI0851.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: SECE_BACLI
Sequence: MGIIKFLKNVGKEMKKVTWPKGKELTRYTITVITTVIFFAIFFALIDSGITQLIRLIVE
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: AROK_STAAR
Sequence: MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEVFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRILRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOA1_MYCA9
Sequence: MGSDTSTQLLGTDGIFFDAAWDVRVTDTSLRDGSHHKRHQFTADEVRAIVAALDGAGVPVIEVTHGDGLGGSSFNYGFSKTPEQELIKLAAQTATNAKIAFLMLPGVGTKEDIIEAQGNGGSICRIATHCTEADVSIQHFGLARERGLETVGFLMMSHTISPEKLAKQARIMADAGCQCVYVVDSAGALVLDGVADRVAAVVAELGSDAQVGFHGHENLGLGVANSIEAVRAGAKQIDGSTRRFGAGAGNAPVEALIGVFDKIGVKTGIDFFDIADAAEEVVAPAMPAECLLDRNALIMGYSGVYSSFLKHAIRQGERYGVPAHQLLHRAGERKLIGGQEDQLIDIALEIQRENAANGQ
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase 1, HOA 1, 4-hydroxy-2-keto-pentanoic acid aldolase 1, 4-hydroxy-2-oxopentanoate aldolase 1.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: Y4140_MYCGI
Sequence: MTRTDTRAGVGALGEQLAVDYLQGLGLRVLARNWRCRYGELDVVVADDAVQAVVFVEVKTRTTDRFGGVAEAVTPVKVRRLRRLAGLWLSEQDARWESVRLDVVTVRIGQGRSPELTHIEGVG
What are the official names of this protein?
UPF0102 protein Mflv_4140.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: NCAP_MUMPJ
Sequence: MSSVLKAFERFTIEQELQDRGEEGSIPPETLKSAVKVFVINTPNPTTRYQMLNFCLRIICSQNARASHRVGALITLFSLPSAGMQNHIRLADRSPEAQIERCEIDGFEPGTYRLIPNARANLTANEIAAYALLADDLPPTINNGTPYVHADVEGQPCDEIEQFLDRCYSVLIQAWVMVCKCMTAYDQPAGSADRRFAKYQQQGRLEARYMLQPEAQRLIQTAIRKSLVVRQYLTFELQLARRQGLLSNRYYAMVGDIGKYIENSGLTAFFLTLKYALGTKWSPLSLAAFTGELTKLRSLMMLYRGLGEQARYLALLEAPQIMDFAPGGYPLIFSYAMGVGTVLDVQMRNYTYARPFLNGYYFQIGVETARRQQGTVDNRVADDLGLTPEQRTEVTQLVDRLARGRGAGIPGGPVNPFVPPVQQQQPAAVYEDIPALEESDDDGDEDGGAGFQNGVQLPAVRQGGQTDFRAQPLQDPIQAQLFMPLYPQVSNMPNNQNHQINRIGGLEHQDLLRYNENGDSQQDARGEHVNTFPNNPNQNAQLQVGDWDE
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PYRDB_SULAC
Sequence: MIQVAGVNFEDPIVIASGIVPPTKEYMQNVCEKYEPSAITSKTLTYSPLEPHRSPTFVKISDNCYLNAIGLGNPGIQILRDLGEIKCKLIISIGGSNVNEYIDAVSKINDIPVMIELNVSSPNRRGFGESNLTYVEEIVKNVKSIVKKPVFVKLGPWDNIVEIAGRALSAGADGLTLINTLKGMLIDVEDFKPILSYGTGGISGKCIHALAVRVIHDVFKEYEPEIIGVGGVFDWRDAIELISVGAKLVGLGTVLVEKGFDVIREIREGIGTYLEEKGLKVEEIRGIGVKR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLA_LISMO
Sequence: MADVRKLKNYIDGEWVESKTDKYEDVINPATGEVLCQVPISTRAELDQAAVIAEQAFEKWSQVAVPRRARVLFGFQQLLIQHKEELARLITLENGKNLSEARGEVQRGIENVEFAAGAPTLMMGDSLASIATDVEAANYRYPVGVVGGIAPFNFPMMVPCWMFPMAIALGNSFILKPSERTPLLMEKLVELFSEAGLPKGVFNVVYGAHDVVNGILENEIIKAVSFVGSKPVGEYVYKTGSANLKRVQALTGAKNHTIVLNDADLEDTVTNVISAAFGSAGERCMACAVVTVEEGIADEFLEALRTAAQNVKIGNGLDDGVFLGPVIREENQKRTIAYIEKGIEEGAKLTVDGRETGLSEGHFVGPTILEDVTTDMTIWKDEIFAPVLSVIRVKNLQEAVRVANQSEFANGACIFTNNAKAIRYFREKIDAGMLGVNLGVPAPMAFFPFSGWKSSFYGTLHANGKDSVDFYTHKKVVTARYSLKGYEE
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase, MSA dehydrogenase, Methylmalonate-semialdehyde dehydrogenase, MMSA dehydrogenase, MSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: COX2_TRIRU
Sequence: MNLVAPTPWGLFFQDSATPQMEGIEELHNNIMFYLTIILFSVTWMMITIIKSFVNTKSPISHKYMNHGTLIELIWTITPAVILILIAFPSFKLLYLMDEVMDPSLVIYGEGHQWYWSYQYPDFTNADGEFVEFDSYIVPESDLEEGTLRMLEVDNRVIIPELTHTRFVISAADVIHSFACPSLGIKCDAYPGRLNQSSVYLNRQGTYFGQCSEICGILHSSMPIVIQSVSLKNFYYD
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CP141_MYCTO
Sequence: MTSTSIPTFPFDRPVPTEPSPMLSELRNSCPVAPIELPSGHTAWLVTRFDDVKGVLSDKRFSCRAAAHPSSPPFVPFVQLCPSLLSIDGPQHTAARRLLAQGLNPGFIARMRPVVQQIVDNALDDLAAAEPPVDFQEIVSVPIGEQLMAKLLGVEPETVHELAAHVDAAMSVCEIGDEEVSRRWSALCTMVIDILHRKLAEPGDDLLSTIAQANRQQSTMTDEQVVGMLLTVVIGGVDTPIAVITNGLASLLHHRDQYERLVEDPGRVARAVEEIVRFNPATEIEHLRVVTEDVVIAGTALSAGSPAFTSITSANRDSDQFLDPDEFDVERNPNEHIAFGYGPHACPASAYSRMCLTTFFTSLTQRFPQLQLARPFEDLERRGKGLHSVGIKELLVTWPT
What are the official names of this protein?
Putative cytochrome P450 141.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUTB_METPB
Sequence: MDDAPAGYRDPSGRHGAVTLTARPEPIAFDTDATALIVVDMQNAYATKGGYLDLAGFDVSATGPVIERIARAVAAARAAGIRVIWFQNGWDPDYVEAGGPGSPNWHKSNALKTMRRRPEMNERLLAKGTWDYALVDALRPEPGDIVLGKPRYSGFYNTPLDSMLRARGIRTLVFTGIATNVCVESTLRDGYHREYFGVVLADATHQAGPPSLQEGALRNIETFFGWVSDVAAFEAALQPDEARRIPA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: TIP51_ORYSJ
Sequence: MANICANMKRCFSPPALRAYFAEFFSTFLFVFIAVGSTISARMLTPDETSDASSLMATAVAQAFGLFAAVFIAADVSGGHVNPAVTFAYAIGGHITVPSAIFYWASQMLGSTFACLVLHYISAGQAVPTTRIAVEMTGFGAGILEGVLTFMVVYTVHVAGDPRGGGFGGRKGPAATALGALVVGAVTGACVLAAGSLTGASMNPARSFGPAVVSGHYSNQAVYWAGPMVGAAVAALVHQALVFPTVPEPAPAPATNESARHGSVQTVVV
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.  May be involved in transport from the vacuolar compartment to the cytoplasm (By similarity).
What are the official names of this protein?
Probable aquaporin TIP5-1, Tonoplast intrinsic protein 5-1, OsTIP5;1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: FETP_DELAS
Sequence: MARTVHCIKLGVDAEGLDFPPYPGELGKRIFEGVSKQAWADWLKHQTMLVNENRLNLADARARQYLARQMENHFFGGGADAAAGYVPPTA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.