PharMolix/UniProtQA huggingface dataset:
Protein: TRM44_CANGA
Sequence: MTEKKTAPSFQFMKDESTSVLGGEWVPMYCTDEPVEFSKGDFETAMLNVIREPNINSTAILRADILAEKFYDLEGNEQELSTDDKPVLSESLPYDADAKLVNIDDITTRKELIENKELELTIVKEFVRRMIPRNPYKDALINQTCLVYNSKKTENKDTSLVLYIPHFEDEADCPFYIPHVQKVAILLHGGILSVHYIPYAGQSEDLRKDNERVVRTAFRLLQTAYKHSKGVMQGYEKRVNHDQVVDRVLFQDTYIQLKKKYSKFLVDNWAESTDPKKHVFEDLAIAAFLLEFWKTQYGDDYKTTMQFRDMGCGNGVLTYILISEGVNGVGIDARKRKSWSIYPTEIQRHLKEQVIIPSILLRPTPDVRRYMPYLEDNGAMFPIKVEDGLIAPATLVYSSADLIASPNVNICEFPDNTFIIGNHSDELTCWIPLLGFPFMVIPCCSHDLSGKKVRFNTRVPKSEKTTPAMKNNIKINSNNVNNSNSTYAGLVNHVEYLAKKVGWKVEKEMLRIPSTRNAAIIGTDNAYAKEFPTPDIYRTIEEEGGALTWVQNTMQLAKASPRNH
What is the function of this protein?
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
What are the official names of this protein?
tRNA (uracil-O(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TRM44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_NECAO
Sequence: MKIIRKNHPLLKIINHSFIDLPTPSNISSWWNFGSLLGICLMIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLSETWNIGIILFFTTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAFVLVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGILLLLMALMILALFFPDVLGDPDNFTPANPLNTPAHIKPXWYFLFAYAILRSIPNKLGGVLALILSILILAAFPLLNTSKQHGLIYRPITQTIYWTFIANLLILTWIGGQPVKYPFTMXGXIASITYFIIIIILMPMSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
Protein: SYK_HELPJ
Sequence: MFSNQYIQQRIHKANSLREEGKNPYKNGLKRSLTNAAFLEKYAYVKGLEEPKDKEKCESVVGRVKLLRLMGKACFIKIEDESAILQAYVSQNELNDEFKSLKKHLEVGDIVLVKGFPFATKTGELSIHALEFHILSKTIVPLPEKFHGLSDIELRYRQRYLDLIVNPGVKDVFKKRSLIVSSVRKFFEMEGFLEVETPMMHPIPGGANARPFITYHNALEIERYLRIAPELYLKRLIVGGFEAVFEINRNFRNEGMDHSHNPEFTMIEFYWAYHTYEDLIELSKRLFDYLLKTLNLDSKIIYNDMEVDFNQTSVISYLDALETIGGISKGILEKEDRLLAYLLEQGIKVEPNLTHGKLLAEAFDHFVEHKLINPTFVTEYPIEISPLARRNDSNPNIADRFELFIAGKEIANGFSELNDPLDQLERFKNQVAEKEKGDEEAQYMDEDYVWALAHEMPPTAGQGIGIDRLVMLLTGAKSIKDVILFPAMRPVKNDFNVEGEE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAOX3_ARATH
Sequence: MATECIATVPQIFSENKTKEDSSIFDAKLLNQHSHHIPQQFVWPDHEKPSTDVQPLQVPLIDLAGFLSGDSCLASEATRLVSKAATKHGFFLITNHGVDESLLSRAYLHMDSFFKAPACEKQKAQRKWGESSGYASSFVGRFSSKLPWKETLSFKFSPEEKIHSQTVKDFVSKKMGDGYEDFGKVYQEYAEAMNTLSLKIMELLGMSLGVERRYFKEFFEDSDSIFRLNYYPQCKQPELALGTGPHCDPTSLTILHQDQVGGLQVFVDNKWQSIPPNPHAFVVNIGDTFMALTNGRYKSCLHRAVVNSERERKTFAFFLCPKGEKVVKPPEELVNGVKSGERKYPDFTWSMFLEFTQKHYRADMNTLDEFSIWLKNRRSF
What is the function of this protein?
Key oxidase enzyme in the biosynthesis of gibberellin that catalyzes the conversion of GA12 and GA53 to GA9 and GA20 respectively, via a three-step oxidation at C-20 of the GA skeleton, and GA25 is also formed as a minor product.  GA53 is less effectively oxidized than GA12.
What are the official names of this protein?
Gibberellin 20 oxidase 3, GA 20-oxidase 3, Gibberellin C-20 oxidase 3.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family. GA20OX subfamily.
Protein: STRN_STRGR
Sequence: MLASGMLLENRLVERRSIIRLVEENFRDHFPSDQELPGLEFFPLGEDSWSYRCGPLWISVRRDLDGHFPGAYEVSLLLSESGKGYVLAPLPGRNGRVVHRIADFPVVVFPYVESATTPPAPPTQEQIDLLIARLGEVHAFEPPASRPVDVPTEDFRFPFENDLDKAVQAALNGDAAAGGPYAGLLAERVDRCQGFLAELREEATRVAGECAARWRGERPALTHGDPSLANVLFTKGVDIIDWGGAMWAPPERDWAALQRVFGTAPRSRPEFLRFYELRWHLAEIAEYATRFTGPHTGDADDDAMWERLTRYLPEPRGAS
What are the official names of this protein?
Protein StrN.
Protein: URED_STAA8
Sequence: MDEQQWTGQLDLTVFFDGNRSVSRDIFFEKALKVIRPVYLNQSTIPTFYIVNVGGGYLDGDRYRMNVNVEDNAKVTLTSQGATKIYKTPSNHVEQYQTFNLKDNAYLEYVADPIIAYENAKFYQHNTFNLNNSSSLFYTDILTPGYSKTGEAFKYQYMHLINEIYIEDELVTYDNLLLNPNKQSINEIGYMEHYSHYGSAYFIHEDVNQKLIDSVYETISSYSNTFDCRVAISQLPTHGFAVRIFAYRTQIIEKILGTIQSYIAENIYDRKLDFLRKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPQB_RHOOB
Sequence: MTPGSRSAMRSRSVCGAIALAVLVTVSGCASLPDSSTPQAIGTINRDSPGSSVAAPAPGREPDLLLRDFFKASTDPTDRHLAARQFLTPGVSGRWDDAASATIVDKVDVLPETRSADQATYTIRANKVGQLEPGGLYVAEEGSFETRISLELQGGEWRISELPAGVILDRAQFLNTYQRKSLYFLDPAGTTVVPDPRWVSGAQDQMASQLIGLLIDGPKAALAPAVRNELGDGVSVRGPITKADGRTAQVGVGLGGIRIDFTGVPPMDAQQKQLFAAQVIWTLANAEISGPYVLLADGEPFDERFPNGWTTADVASMNPFATSSATVGLHALREGSMVSVTETGVTPVPGYFGAARNMRSLALSQDGKLVAAVADTGRPAPEPASSLMVGAYEDGAASVLEGGAITRPTWAPDNSAIWAAVNGNTVIRVLREPGTGRTSVVNVDAGAVTALGATITELRLSRDGVRAALIVDGKVYLAIVTQMPGGAYALTNPRAVAIGLGSPALSLDWSTSDTIVVARAASDIPVVQVAVDGSRMDALPSRNLTAPVVAVDASTTTEFVADSRAVFQLNNNDPAGDRYWREVPGLTGVKAIPVLPG
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS11_STRAW
Sequence: MPPKGRQGAAKKVRRKEKKNVAHGHAHIKSTFNNTIVSITDPSGNVISWASAGHVGFKGSRKSTPFAAQMAAESAARRAQEHGMRKVDVFVKGPGSGRETAIRSLQATGLEVGSIQDVTPTPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GRCA_SALG2
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKSGFAEDEVVAVSKLGEIEYREIPMEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: O16C_CONCT
Sequence: CKGKGQSCSKLMYDCCTGSCSRRGKC
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).  This toxin blocks N-, P- and Q-type calcium channels.
What are the official names of this protein?
Omega-conotoxin CVIC.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DPO3_CLOTE
Sequence: MELAKILEDNTFSQDSLEGIRVHRIQYFKKSNKLKVIVKSKKEVNNNQITEIKKVFFKKFQYFKEIEVLSYRDVSGINLKDICEKYWIDIVNSILTYIPFCKECLISSKRKVIDENTLKLQYGNDFLYNILKEKNFEKILSSTIKDVFGVECKVKFILDKSNGKCNYLDFKEEQEALIIKNIIKESRIEKTIPKKDNNYNKREENKNSSIIVGKNINEDPVDISNIDETSGIISICGDVFKTKIIETKTGRKIVTFYITDYTSSITVKLFPKPKDTERVIEEIKEGLYCKIRGEVVNDSYAREIVIMARDIVKLNKIEKMDIAEEKRVELHLHTKMSAMDGMNSAESLIKRAAKWGHKAVAITDHGVVQAYPEAMEAAKKYNIKIIYGVEGYLVDDGIPIAINAGHRTLEDSYVVFDIETTGFSNKNDKIIEIGAVKIKEGKVVDKYSTFVNPERIIPEKIIELTGIHDYMVKDAPKIEEVLPKFIDFIEDSILVAHNANFDVSFIKKNCKDFGIHFNNPILDTIPLCKFLYPELKRYKLNVVAKHLGIPLLNHHRAVEDAKTTGDILLKAFEDLKDKEIMNLNMLNEEYFKNQDIKKSPTYHVIILVKNKIGLKNLYKLISESHLNHFYKKPRMPKSLINKYREGLMIGSACEAGQVYKEVLMDKSKEELKEVISFYDYLEIQPIKNNYFMIRNGIVKDEEELRDINKKIYNLAEENNMPVVATCDVHFLDKKDEVFRKILMAGQGFSDAENQPPLYLRTTDEMLKEFEYLGKEKAYKAVVTNTVKIADSIDNIKPIPDETFPPKIEGSEEEVRKMTIEKAHSIYGEVLPEIVEKRLEKELNSIINNGYAVLYLIAHKLVDKSVQDGYLVGSRGSVGSSLVATMTDITEVNGLPPHYVCPGCKYNEFITDGSVSSGADLPDKNCPNCGVLLSKDGHDIPFETFLGFEGDKEPDIDLNFSGEYQAVVHKYTEVLFGEGKVFKAGTIGTIAEKTAYGFVKKYISEKDLNVRQAEIERLTLGCSGVKRTTGQHPGGIMVVPQDNEIFNFTPIQRPADDNDTDIITTHFDYHSISGRLLKLDILGHDDPTVLRMLQDLTGVDPKKIPLADPKVMSLFTSPKALGVNAEELKCEVGTYGLPEFGTKFVRQMLVDTQPNSFSDLVRISGLSHGTDVWLNNAQYYIKEGYTTLKDCIATRDDIMTYLIQKDLPPKIAFTIMEKVRKGKGLTEEHEAIMREHDVPGWYIESCKKIKYMFPKGHAVAYVMMAVRIAYFKVYYPTAYYATYFSVRASDFDAETVFKGEEAILNKIDEINSLGNNVTQKDKGLLTVLEICHEMNLRGIKFLKADLYKSNASKFLIEEEGIRIPLSAIQGVGENAAKNIVEAREEGEFISKEDLNKRGKATKTVIENLENHGCLRGLPESNQLSLFNL
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAX2_ARATH
Sequence: MSCCKVPVLIEAQVEMVSANELENKSLFRQEEDATQTKEASLMEQGSLSTSFPQHTPKAPKNSVLNSIKIVIFCNKLNLLLPFGPLAILVHYMIDSKGWVFLLTLVGITPLAERLGYATEQLACYTGPTVGGLLNATFGNVTELIISIFALKNGMIRVVQLTLLGSILSNMLLVLGCAFFCGGLVFYQKDQVFDKGIATVNSGLLLMAVMGILFPAVLHYTHSEVHAGSSELALSRFSSCIMLIAYAAYLFFQLKSQSNSYSPLDEESNQNEETSAEDEDPEISKWEAIIWLSILTAWVSLLSGYLVDAIEGASVSWNIPIAFISTILLPIVGNAAEHAGAIMFAMKDKLDLSLGVAIGSSIQISMFAVPFCVVIGWMMGQQMDLNFQLFETAMLFITVIVVAFFLQEGSSNYFKGLMLILCYLIVAASFFVHEDPHQDGI
What is the function of this protein?
Vacuolar cation/proton exchanger (CAX).  Translocates Ca(2+) and other metal ions into vacuoles using the proton gradient formed by H(+)-ATPase and H(+)-pyrophosphatase.
What are the official names of this protein?
Vacuolar cation/proton exchanger 2, Ca(2+)/H(+) antiporter CAX2, Ca(2+)/H(+) exchanger 2, Protein CATION EXCHANGER 2.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: CKB3_CAEEL
Sequence: MKPIEKLFVGNSLDSVAVLQKALDFGIDFLGDEWKNVNRSEVTVTRILGGQSNHMFHVTSSTSATSFVLRIHREGQSQFDTDIVNFAIFSERGLGPKLYGFFEEGRMEEFLPSVTLKLNDVLNTEISRKIGAAFPKYHAINVPVSKSRRCFQIMRESLHDYQALGGGDFAIFPTVVTYSEHPKSISIKDLLTEIDLLEKWSIDLFENTLVFCHNDLTSSNILQLNSTGELVFIDWENASYNWRGYDLAMHLSEAAVIRNTCPPGIVINEELTDNPPNLQAFCEAYVDSENKIKGLLSSNISSQVNSLIQECKFFWPITHLFWACFIMKLGLFECNREIKLNAQAREHLAVYFHLRSRSEMIYKKLSEN
What are the official names of this protein?
Putative choline kinase B3.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
Protein: SAHH_FLAJ1
Sequence: MSTTTTPYVAFKVKDISLAAWGRKEIELAEAEMPGLMALRAEYKDEQPLKGARIAGCLHMTIQTAVLIETLIALGAEVTWSSCNIFSTQDQAAAAIAAAGISVYAWKGLDEESFDWCIEQTLFFGEERKPLNMILDDGGDLTNMVIDRYPELVAGIKGLSEETTTGVHRLYERVKAGTLPMPAININDSVTKSKFDNKYGCKESAVDAVRRATDLMLAGKRVVVCGYGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMDGYEVKKLNTVIANADIIITTTGNKDIVLGEHFEQMKDKTVVCNIGHFDNEIDMAWLNKNHGASKIEIKPQVDKYNINGKDIIILAEGRLVNLGCATGHPSFVMSNSFTNQTLAQIELWNNSAAYKNEVYMLPKHLDEKVAALHLAKLGVELEVLREDQAAYIGVEVQGPFKPEYYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APMT1_AMOMA
Sequence: MFTLKKSLLLLFFLGTISLSLCEQERGADEEENGGEVTEEEVKRNILSGIANGINRVLSWFG
What is the function of this protein?
Antimicrobial peptide.  Active against a variety of Gram-negative and Gram-positive bacterial strains.  Not active against fungi.  Shows weak hemolytic activity against human erythrocytes.
What are the official names of this protein?
Amolopin-p-MT1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_BURVG
Sequence: MSMFNKVVKEFQWGQHKVRLETGEVARQASGAVIVDVEDTVVLATVVGAKSAKPGQDFFPLTVDYLEKTYSAGKIPGGFFRREGRPSEHETLTSRLIDRPLRPLFPEGFYNEVQVVIHVLSVNPDIPADIPALIGASAALAVSGLPFNGPVGAARVAYIDNAYVLNPTRDQIKASSLDLVVAGTERAVLMVESEADQLPEDVMLGAVVFGHEQMQIAIDAIHELVREGGKPEWDWQPAPKNEALIARVTELAHGDLLAAYQLRDKQARSTKLKEVYAATSAKLEEDALAAGTVAADKATVGNILFDIEAKIVRSQILNGEPRIDGRDTRTVRPIEIRTGVLPRTHGSALFTRGETQALVVATLGTKGDEQIIDALEGEYRERFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALVKCLPSADEFGYSIRVVSEITESNGSSSMASVCGGCLALMDAGVPMKAHVAGIAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTEHGVTALQMDIKIQGITKEIMQVALAQAKEGRMHILGKMTSAVSGANTQLSEFAPRMITIKINPEKIRDVIGKGGSVIRALTEETGTTIDISDDGVVTIASTSSEGMAEAKKRIENITAEIEVGQVYEGTVLKLLDFGAIVNLLPGKDGLLHISEIVNERVKDINDYLKEGQQVKVKVIQTDEKGRVRLSAKALLNEAAAASQSDTPPQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJHX_ECO45
Sequence: MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRAQLDNR
What are the official names of this protein?
UPF0386 protein YjhX.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: CSD_STAAS
Sequence: MAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF
What is the function of this protein?
Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
What are the official names of this protein?
Probable cysteine desulfurase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
Protein: AMRZ_PSEO1
Sequence: MRPLKQAIYSSRTADKFVVRLPDGMRERIAEVARNHHRSMNSEIIARLEQSLIQEGALGEELSMRLDSPELSLHERELLQRFRQLSHRQQNALVSLIAHDAEMAADAT
What is the function of this protein?
Functions as both a transcriptional activator and repressor of multiple genes encoding virulence factors as well as genes involved in environmental adaptation.  Represses genes involved in iron homeostasis (PubMed:24670089, PubMed:29386661).  Modulates intracellular levels of c-di-GMP which in turn regulates swimming motility and biofilm formation (PubMed:29386661).
What are the official names of this protein?
Transcription factor AmrZ.
Protein: VPK6_HUMAN
Sequence: WASQVSENRPVCKAIIQGKQFEGLVDTGADVSIIALNQWPKNWPKQKAVTGLVGIGTASEVYQSTEILHCLGPDNQESTVQPMITSIPLNLWGRDLLQQWGAEITMPAPSYSPTSQKIMTKMGYIPGKGLGKNEDGIKIPVEAKINQEREGIGNPC
What is the function of this protein?
Retroviral proteases have roles in the processing of the primary translation products and the maturation of the viral particle.  Endogenous Pro proteins may have kept, lost or modified their original function during evolution.
What are the official names of this protein?
Endogenous retrovirus group K member 6 Pro protein, HERV-K(C7) Pro protein, HERV-K(HML-2.HOM) Pro protein, HERV-K108 Pro protein, HERV-K_7p22.1 provirus ancestral Pro protein, Protease, Proteinase, PR.
What is the protein family that this protein belongs to?
Belongs to the peptidase A2 family. HERV class-II K(HML-2) subfamily.
Protein: SMD3_HUMAN
Sequence: MSIGVPIKVLHEAEGHIVTCETNTGEVYRGKLIEAEDNMNCQMSNITVTYRDGRVAQLEQVYIRGSKIRFLILPDMLKNAPMLKSMKNKNQGSGAGRGKAAILKAQVAARGRGRGMGRGNIFQKRR
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077).  As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3.
What is the protein family that this protein belongs to?
Belongs to the snRNP core protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN- mediated assembly into core snRNPs occurs in the cytosol before SMN- mediated transport to the nucleus to be included in spliceosomes.
Protein: NDK_SALNS
Sequence: MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLESENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSLESAQREIAFFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRAN_ECOBW
Sequence: MATVPTRSGSPRQLTTKQTGDAWEAQARRWLEGKGLRFIAANVNERGGEIDLIMREGRTTIFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDAFNDHS
What are the official names of this protein?
UPF0102 protein YraN.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: Y1261_STRR6
Sequence: MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDSYKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK
What are the official names of this protein?
UPF0223 protein spr1261.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: PUR5_LIMF3
Sequence: MNRYQEAGVDVNAGYELVKRIKENVKSTNRPGALGGIGAFGGLFDLGELKVKHPVLVSGTDGVGTKLLIAKAMDQHDTIGIDVVAMCVNDVLAQGAEPLYFLDYIATGHNDPAKMADIVAGVAEGCRQAGAALIGGETAEMPDMYDQDEYDLAGTVTGVVEKDDLLTSDQPQAGAILLGLASSGIHSNGFSLVRQILFKDHQVDLAATPAKLGGQTVGQAVLAPTKIYVKPVLPLLKDHLVEGVAHITGGGLIENLPRMFGDDLQAQVDSSAWPSLPVFDYLKELGGLSDDDCWQTFNMGLGMILAVQPDLVDQVKSRLNQAGEACYQVGQLVNRPAGEEKIVIK
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCC1G_RAT
Sequence: MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPSVRQEVENRPPVSPAPEVSRPGSHDSSITEAPILDPSTPLPALTRLPCSHSSRPSAPGGRSLNCLVNGSLRISSSLVPMQQGPLATGPCGCCSSCLNIGNKGKSSYCSEPTLFRKANKKQNFKSEVMVPVKAGGSTHCRAGQTGVCLIM
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade.  In vitro phosphorylates transcription factor CREB1 (By similarity).
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type 1G, CaM kinase I gamma, CaM kinase IG, CaM-KI gamma, CaMKI gamma, CaMKIG, CaMK-like CREB kinase III, CLICK III.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Protein: PBUG_BACSU
Sequence: MKTFFQFDELGTSYRNEIIGGLTTFLSMAYILFVNPITLALESVKDFPEALRIDQGAVFTATALASAAGCILMGLIARYPIAIAPGMGLNAFFAFSVVLGMGISWQAALSGVFISGLIFVALSLTGFREKIINAIPPELKLAVGAGIGLFITFVGLQGSGIITANPSTLVTIGNIHSGPVLLTIFGVIVTVILMVLRVNAGVFIGMLLTAVAGMIFGLVPVPTQIIGSVPSLAPTFGQAWIHLPDIFSVQMLIVILTFLFVGFFDTAGTLVAVATQAGLMKENKLPRAGRALLADSSSIVIGAVLGTSTTTSYVESSSGVAAGARSGFAAIVTGILFLLATFFSPLLSVVTSNVTAPALIIVGALMVAPLGKIAWDKFEVAVPAFLTMIMMPLTYSIATGIAIGFIFYPITMVCKGKAKEVHPIMYGLFVVFILYFIFLK
What is the function of this protein?
Involved in the uptake of the purine bases hypoxanthine and guanine.
What are the official names of this protein?
Guanine/hypoxanthine permease PbuG.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREE_ARTS2
Sequence: MIIEKILGNLHELPASEAGAFAGLHQEKVVLPSAQLVKRIQRVTTDHGKELGIRLPAGSGDLRDGDILHVAETNMIVISVLPTDVLVVAPRSIHEMGVVAHSLGNRHLQAQFFDAGSEYAADVMVCQYDHTVEDYLKHVGVPYERQERVMPVPFRHAEHSH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGD1_HUMAN
Sequence: MHGHRAPGGAGPSEPEHPATNPPGAAPPACADSDPGASEPGLLARRGSGSALGGPLDPQFVGPSDTSLGAAPGHRVLPCGPSPQHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQSLEPHPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPLEPIPPPPSRPLPADPRVAKGLAPRAEASPSSAAVSSLIEKFEREPVIVASDRPVPGPSPGPPEPVMLPQPTSQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDSISSPSNSEETCFVSDDGPPSHSLCPGPPALASVPVALADPHRPGSQEVDSDLEEEDDEEEEEEKDREIPVPLMERQESVELTVQQKVFHIANELLQTEKAYVSRLHLLDQVFCARLLEEARNRSSFPADVVHGIFSNICSIYCFHQQFLLPELEKRMEEWDRYPRIGDILQKLAPFLKMYGEYVKNFDRAVELVNTWTERSTQFKVIIHEVQKEEACGNLTLQHHMLEPVQRIPRYELLLKDYLLKLPHGSPDSKDAQKSLELIATAAEHSNAAIRKMERMHKLLKVYELLGGEEDIVSPTKELIKEGHILKLSAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNLPRTFLVSGKQRSLELQARTEEEKKDWVQAINSTLLKHEQTLETFKLLNSTNREDEDTPPNSPNVDLGKRAPTPIREKEVTMCMRCQEPFNSITKRRHHCKACGHVVCGKCSEFRARLVYDNNRSNRVCTDCYVALHGVPGSSPACSQHTPQRRRSILEKQASVAAENSVICSFLHYMEKGGKGWHKAWFVVPENEPLVLYIYGAPQDVKAQRSLPLIGFEVGPPEAGERPDRRHVFKITQSHLSWYFSPETEELQRRWMAVLGRAGRGDTFCPGPTLSEDREMEEAPVAALGATAEPPESPQTRDKT
What is the function of this protein?
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP.  Plays a role in regulating the actin cytoskeleton and cell shape.
What are the official names of this protein?
FYVE, RhoGEF and PH domain-containing protein 1, Faciogenital dysplasia 1 protein, Rho/Rac guanine nucleotide exchange factor FGD1, Rho/Rac GEF, Zinc finger FYVE domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cytoskeleton. Note=Associated with membrane ruffles and lamellipodia.