PharMolix/UniProtQA huggingface dataset:
Protein: C516B_DICDI
Sequence: MYLILSLIIFLAYVAFHKKRTNGMPPGPFPLPIIGNLHQLGKSPYKSLKSFSDKYGGLTTIFLGSVPTVLISEPNILREIIIKNNDSIIDRYISDSGLIIGGERNLLFSKGSFWIKYRKIFSSAMTNARKFNIASRIEQQAISLNNYFGTYANSKQAINPHDYIRRYSLNGVIDYSFSDSVEYESDTHHIVIRAAEIMEEILATGNPHDYLPFLKPFYTKKRNTLAMAVGQVWDYCNDAITVHRKTLDHEKPRDLLDLILMEIEKSEEKQFYDDDSLSKCLTDLIVAGHETVAITLGWMILFLSNHQDVQQKVYDELINVVGKGNLPALVHRKDTSYLNACIQETMRIRTAAPLALPRIASEDIKVGGYTIPKGTQVMMSVYGMASDERYWKDPHIFNPERWLSSNHSTENGGGGGGVVGNSSQSEVFIPFGVGPRMCVGMGVAKDELYYCASQMFMNFKWSPVNDKPIDDEGVARIALEYKEYQVVLERRK
What are the official names of this protein?
Probable cytochrome P450 516B1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y212_BOTFU
Sequence: MADPSLYTYPSPLQGYENLAPLGTEVSPDGKSLLNPETGIKSKSYEKFTEPLDSGIRGAFDVHIYHFQKNKEQAKFARELWERIRREFPELRIYRFWEEPIGPHPVAMFEVNLFTPEQFGAFIPWLVINRGPLSALVHPNTVDEKGELLDEERDHTQRAIWMGEQLPLDLSLVKRLKQQKAAH
What are the official names of this protein?
Uncharacterized 21.2 kDa protein.
What is the protein family that this protein belongs to?
To A.muscaria DOPA 4,5-dioxygenase.
Protein: Y0679_EMENI
Sequence: MYLRAVHAEAQISILQQLIRDNPLGILTTAIKSPLYPLIQSSHIPFVLDAPETSDGSLSNGVLRGHMAKQNPQAKALIEALTAQQEQGNTSLELSDEVLVLFNGPHHHYVTPKFYTETKPATGKVVPTWNYAAAQAYGKIRIYCDSKSEETMTFLQKQIEELSHQSETSIMKYSSPWQVSDAPVSYVELLKKNIIGIEITIDRLQGKFKMSQEMGQGDRDGVISGFENLGTDAGKCIANIVRERGEMKDKK
What are the official names of this protein?
Uncharacterized protein AN0679.
What is the protein family that this protein belongs to?
Belongs to the PaiB family.
Protein: TRPB_ALIFM
Sequence: MAKLDAYFGEYGGQYVPQILVPALEQLEQAFIDAQEDPDFRAEFMTLLQEYAGRPTALTLCRNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQALLAKRMGKDEIIAETGAGQHGVATALACALLGLKCRVYMGAKDVERQSPNVFRMELMGAEVIPVHSGSATLKDACNEALRDWSATYETAHYLLGTAAGPHPFPTIVREFQRMIGEETKMQILAREGRLPDAVIACVGGGSNAIGMFADFIEEESVKLIGVEPAGKGIDTDQHGAPLKHGKTGIFFGMKAPLMQDEHGQIEESYSVSAGLDFPSVGPQHAHLNAIGRAEYGAVTDDEALEAFKILARNEGIIPALESSHALAYALQLAQAEPEKEQLLVVNLSGRGDKDIFTVHDILKEKGEI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: MYO1D_XENLA
Sequence: MAEQEGLQYGKADFVLMDSVTLPEFMENLKLRFEKGRIYTFIGEVVVSVNPYKNLPIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRCKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHISNYLLEKSRVIVQQLGERNFHSFYQMILGAPEQTLRSLHLQRDISSYAYTRSLAQLKSSNNDAGDFKEVAEAMKVIGFKPEEIQTVYKILAAILHLGNLKFIVDGDTTLIENGKVVSVVADLLGTRSEQVEKALLFRTVATGRDVIDKQHTEKEANYGRDAFAKAIYERLFCWIVNRINDVIDVKQQDASLHGKNTVIGVLDIYGFEIFDNNSLEQFCINYCNEKLQQLFIQLVLTQEQAEYQREGIPWKHIDYFDNQIIVDLVEQQHKGIISLLDDACMNVGKVTDDMFLEALNKQLGKHAHYSSRKVCATDKALEYNRDFRIRHYAGDVVYSVVGFIDKNKDTLFQDFKRLMFNSSNPVLKTMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNEKKSPALFDEVRCRHQVEYLGLLENVRVRRAGFAYRQVYDKFLHRYKLISSLTWPNHSLPSDRIAVERFMVDCGLNHDAAYGKTKIFIRTPRTLFSLEERRSEMLIRIILFLQKLWRGTLARRRCKRIRAGLTILRYYRRYKVKSYLREVMHRFNGVKNSRDYGKHVKWPTPPRVLRRFQEALQNIYNRWRGYQIIKSLPPAEIPKVRAKVAAFENLKGHRVDMGLQRCWEGSYLASNQENARNSNQFVSRSNELQRKDKFMQALFSCHVQKVNRFNKVQDRAIFITDRHLYKMDPGKEYKVMTSTPLYNVSGISVTSGKDQLVVFHMKDNKDLIVCLGCSGQGPYDSRIGELVGVLANHFKSERRPLQVTVSHPIQCRQHGRSCSITVETKINQSQPQFTKNRAGFTLSVPAN
What is the function of this protein?
Unconventional myosin that functions as actin-based motor protein with ATPase activity (By similarity).  Plays an important role in the establishment of left-right asymmetry during embryonic development (PubMed:29478852).  Required for normal cilia orientation, and for normal, directed flow at the transient ciliated epithelium that functions as left-right organizer during embryogenesis (PubMed:29478852).  Plays a role in endosomal protein trafficking, and especially in the transfer of cargo proteins from early to recycling endosomes (By similarity).  Required for normal planar cell polarity in ciliated cells, for normal rotational polarity of cilia, and for coordinated, unidirectional ciliary movement (By similarity).
What are the official names of this protein?
Unconventional myosin-Id, Unconventional myosin 1d.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm. Perikaryon. Cell projection, dendrite. Early endosome. Cytoplasm, cell cortex. Note=Colocalizes with the actin cytoskeleton in the cell cortex close to the apical cell membrane. Colocalizes with cytoplasmic puncta that are reminiscent of transport vesicles.
Protein: P2RX3_RAT
Sequence: MNCISDFFTYETTKSVVVKSWTIGIINRAVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKVKGFGRYANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPENEEKYRCVSDSQCGPERFPGGGILTGRCVNYSSVLRTCEIQGWCPTEVDTVEMPIMMEAENFTIFIKNSIRFPLFNFEKGNLLPNLTDKDIKRCRFHPEKAPFCPILRVGDVVKFAGQDFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDGVSEKSSVSPGYNFRFAKYYKMENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADHYKARKFEEVTETTLKGTASTNPVFASDQATVEKQSTDSGAYSIGH
What is the function of this protein?
Receptor for ATP that acts as a ligand-gated cation channel (PubMed:7566120, PubMed:7566119).  Plays a role in sensory perception.  Required for normal perception of pain.  Required for normal taste perception (By similarity).
What are the official names of this protein?
P2X purinoceptor 3, P2X3, ATP receptor, Purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_EHRCJ
Sequence: MARIAGVNIPTNKRVVIALTYIYGIGLSLANRICEGCNIDHNVRVVNLSDDEIIRIRNFIRENYIVEGDLRKEVSMNIKFLTDIGCYRGLRHRRGLPVRGQRTHTNAKTRKGRSKLPVAAKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: OSW5_LACTC
Sequence: MSFTSIFIALLYLGGFLIILVTASAVILPLLITSLFFATGVVLCGFLSNKSYKLALRAYNLATPHTRSSLQAAADHLAPLDSVETVSPKEELLHKIHHFYKKSDSNVRTPIVVSGSEIPKSVIKVSEGT
What is the function of this protein?
Involved in spore wall assembly.
What are the official names of this protein?
Outer spore wall protein 5.
What is the protein family that this protein belongs to?
Belongs to the OSW5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PETL_DAUCA
Sequence: MPTITSYFGFLLAALTVTSALFIGLSKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TE63_HASHE
Sequence: VLFTPPELLGCGNRCSDDCCKWGRCQPGCTD
What are the official names of this protein?
Augerpeptide hhe6.3.
What are the subcellular locations of this protein?
Secreted.
Protein: SYL_RICAE
Sequence: MNQIEQKWQYIWQEEKAFEVSNASSKPKYYVLEMLPYPSGKIHVGHVRNYSIGDVIARFMTMQGFNVLHPMGWDAFGLPAEHAAIKNNSHPKKWTYSNIKNMKKQLKSMGFSYDWSREINSCDPEYYKHEQKFFLELYERNLAYQKESFVNWDPVDNTVLANEQVVDGRGWRSGAIVVKRYLKQWFLKITDYAEELLNEIQNLKEWPEAVRSMQEKWIGKSIGANFHFKIKDNEETTIEVFSTKPETIFGASFIGIAFNHPIIERLVSKTPEILAFITQCSHITRSSELEKTEREGVFTGLFVIHPFDSNIVLPVIITNFVLMDYGTGAIFGCPAHDECDHELAVKMNLSIKQVIKADMDVQKTAYTEDGILINSDFLNGLTSHEAKQEVIGEFEKLGIGKRSVNYRLKDWGISRQRFWGCPIPMIHCEICGIVPVPYKDLPVILPDDVNFDGHGNPLDHHPSWKHVNCPKCDKPAVRETDTFDTFFESSWYFMRYCNSNATEMTDKKACDYWLPVDKYIGGIEHAVMHLLYARFFTKVMNEQNYVSVREPFKGLFTQGMVLHATYKDEHNNWLYPEEVVKKGNEFFHKESNNRVVQGRIEKMSKSKKNLIDLETMQEQYGADAIRLFVLSDSPPEKDLEWSASGIEGCSRFINKLEYMFKAIDSLKDDVNSEVNKELNRLVHFTIKHVAEDIKHFALNRAIARMRELSNAISAEISKDKIDVKTVRHGFNVLVQLLNPFIPHITEEIWQKLGNKERLYNLSFPAFDESMLELDTYIMAVQVNGKLRDTYEFKTSVSEDEIKQVTVSLPKVQKFLEGQEPKKIILVPRKIVNILV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAFB2_HUMAN
Sequence: MAETLPGSGDSGPGTASLGPGVAETGTRRLSELRVIDLRAELKKRNLDTGGNKSVLMERLKKAVKEEGQDPDEIGIELEATSKKSAKRCVKGLKMEEEGTEDNGLEDDSRDGQEDMEASLENLQNMGMMDMSVLDETEVANSSAPDFGEDGTDGLLDSFCDSKEYVAAQLRQLPAQPPEHAVDGEGFKNTLETSSLNFKVTPDIEESLLEPENEKILDILGETCKSEPVKEESSELEQPFAQDTSSVGPDRKLAEEEDLFDSAHPEEGDLDLASESTAHAQSSKADSLLAVVKREPAEQPGDGERTDCEPVGLEPAVEQSSAASELAEASSEELAEAPTEAPSPEARDSKEDGRKFDFDACNEVPPAPKESSTSEGADQKMSSFKEEKDIKPIIKDEKGRVGSGSGRNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPGARCYGFVTMSTSDEATKCISHLHRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEKLSSVDRHHSVEIKIEKTVIKKEEKIEKKEEKKPEDIKKEEKDQDELKPGPTNRSRVTKSGSRGMERTVVMDKSKGEPVISVKTTSRSKERSSKSQDRKSESKEKRDILSFDKIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGRRPYDLDRRDDAYWPEGKRVAMEDRYRADFPRPDHRFHDFDHRDRGQYQDHAIDRREGSRPMMGDHRDGQHYGDDRHGHGGPPERHGRDSRDGWGGYGSDKRLSEGRGLPPPPRGGRDWGEHNQRLEEHQARAWQGAMDAGAASREHARWQGGERGLSGPSGPGHMASRGGVAGRGGFAQGGHSQGHVVPGGGLEGGGVASQDRGSRVPHPHPHPPPYPHFTRRY
What is the function of this protein?
Binds to scaffold/matrix attachment region (S/MAR) DNA.  Can function as an estrogen receptor corepressor and can also inhibit cell proliferation.
What are the official names of this protein?
Scaffold attachment factor B2, SAF-B2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: UTP11_HUMAN
Sequence: MAAAFRKAAKSRQREHRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNKHVFFFDTKKEVEQFDVATHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRKR
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
Probable U3 small nucleolar RNA-associated protein 11, U3 snoRNA-associated protein 11, UTP11-like protein.
What is the protein family that this protein belongs to?
Belongs to the UTP11 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MED7_DICDI
Sequence: MNTSQQQQQQQQQQQQQQQQQQQTPQQVENVSAFPPPPPFYKLYLNYKKDVDYSKPTTENSKKNDTPEGNESTIEKNIDNSDEMNIDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKATTSTNKKIELNKPLAPPLPPKVGANYVQFGQTYSTVDMLPSLDESGAKQLYPKGDIEPISELKKLNRSILFNYLQLLETLIENPKNYQSKIEDISLLFINFHHLLNSYRPHQARETLLSIMNEQIKQKNQSNESIKKALDICKESLMNSFKNLNIEDKQIDSATPLPTNITSPTKNLMSPTKLNNSQDVNMNENNDDDEDKEINWMDQLLDEMLKIN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 7, Putative mediator complex subunit 7.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DTD_HAEIN
Sequence: MIALIQRVSQAKVDVKGETIGKIGKGLLVLLGVEKEDNREKADKLAEKVLNYRIFSDENDKMNLNVQQAQGELLIVSQFTLAADTQKGLRPSFSKGASPALANELYEYFIQKCAEKLPVSTGQFAADMQVSLTNDGPVTFWLNV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, D-tyrosyl-tRNA(Tyr) deacylase, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37_METTH
Sequence: MKGTPSFGKRNKNLHIRCRRCGKNSYHVRKKVCAACGFGRSRRIRRYSWQNKKITGQRLK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: USPB_SHIFL
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THIC_BURO0
Sequence: MNANPKFLSADAHVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTGFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQGWIEARGDTEVLPGLSSQYGLERAADPATADLRFPGLHRHPRRAQPGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYIESLKSSGPNGAKLAAMMGRQHPGQAFGAAAFGANALAEITPEFVRDEVARGRAIIPANINHPESEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFNIGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSETEALKKGMEVKAVEFVKTGAEIYHRQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RPOB_LEGPA
Sequence: MAVAEAKPQYSHAEKKRFRKSFGKQTDIMPIPNLLEIQLKSYRDFLQTDTKLSEQLNTGLHAAFSSVFPIESFSGNARLEYVGYKLGEPAFDVRECKLRGLTYSAPLRVKIRLVVLDKDASDDPKPIKDIREQDVFMGEIPLMTDVGTFVVNGTERVVVSQLHRSPGVIFEHDKGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDCVYVRIDRRRKLPVSILLRALGYEAEDILSEFFETTRCHLKNGEYHIDLIPQRLRGEIASFDIHVPETGELIVEQGRRITARHIKQMEKSQMQDLVVPRDYLIGKTLAKNIIDTSTGEFLAQANDEITEELLDAMANHGILQIDMIYTNDLDHGSYISDTLKIDPTGSQLEALVEIYRMMRPGEPPTKEAAEALFKNLFFVEERYDLSAVGRMKFNRRVGIKSDEGPGTLTKEDILSVIKTLIDIRNGIGMVDDIDHLGNRRVRSVGEMTENQFRVGLVRVERAVKERLSLVESENLMPQDLINAKPVSAAIKEFFGSSQLSQFMDQVNPLSGVTHKRRVSALGPGGLTRERAGFEVRDVHTTHYGRVCPIETPEGPNIGLINSLSVYARTNEYGFIETPCRKVVNGRVTDEVEYLSAIEEVDQYIAQSNVELDAQGNILADLVPCRHQNEFSLTTPDKINYMDVSPKQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRSEKPLVGTGMERIVASDSGVSVVAKRGGVIDLVDASRIVVRVNDDETTAGETGVDIYNLTKYFRSNQDTCINQRPIVSTGDRIQRGDVLADGPCTDMGELALGQNLLVAFMPWNGYNFEDSILISERIVHDDRFTTIHIEELTCIARDTKLGTEEITADIPNVGESALSNLDESGVVYIGAEVKAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPSGMNGTVIDVQVFTRDGLEKDARAKSIEEEHLARVRKDLIDERRIREEDIYHRVSHLLLDKVATGGPGSLKPGSKITQDYLDKVEREKWFDIRIEDDAVSQQLEQLSKQLELLTKEMEKRFNDSRKKIIQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISIVVPVEDMPHMEDGTAVDIVLNPLGVPSRMNIGQVLETHLGLAAKGLGRKIAQMLDERQTPEAIKAYLEKIYNHDGVQRVNLKCLNDDELMTLADNLRAGVPMATPVFDGATEQEIKSMLQLADLPADGKTVLIDGRTGNKFDNTVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVGGRTKIYKNIVDGDHRMDPGMPESFNVLLKEIRALGIDIELEHD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: COX2_CANLU
Sequence: MAYPFQLGLQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETVWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLNFDSYMIPTQELKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLMAMRPGLYYGQCSEICGSNHSFMPIVLEMVPLSYFETWSALMV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: FIP1_MOUSE
Sequence: MSAGEVERLVELSGGTGGDEEEEWLYGGPWDVHVHSDLAKDLDENEVERPEEENASANPPSGIEEEAAENGVAKPKVTETEDDSDSDSDDDEDDVHVTIGDIKTGAPQYGSYGTAPVNLNIKAGGRVYGNTGTKVKGVDLDAPGSINGVPLLEVDLDSFEDKPWRKPGADLSDYFNYGFNEDTWKAYCEKQKRIRMGLEVIPVTSTTNKITVQQGRTGNSEKEAALPSTKAEFTSPPSLFKTGLPPSRNSTSSQSQTSTASRKASSSVGKWQDRYGRAESPDLRRLPGAIDVIGQTITISRVEGRRRANENSNIQVLSDRSATEVDNNFSKPPPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPITVPPPGFPPPPGAPPPSLIPTIESGHSSGYDSRSARAFPYGNVAFPHLTSSAPSWPSLVDTTKQWDYYARREKDRDRDRERDRDRERERDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERHRASREKEERHRERRHREKEETRHKSSRSNSRRRHESEEGDSHRRHKHKKSKRSKEGKEAGSEPVPEQESTEAAPAE
What is the function of this protein?
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.  FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition.  Binds to U-rich RNA sequence elements surrounding the poly(A) site.  May act to tether poly(A) polymerase to the CPSF complex (By similarity).
What are the official names of this protein?
Pre-mRNA 3'-end-processing factor FIP1, FIP1-like 1 protein.
What is the protein family that this protein belongs to?
Belongs to the FIP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTHB_ECOLI
Sequence: MTHIRIEKGTGGWGGPLELKATPGKKIVYITAGTRPAIVDKLAQLTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQYIVEDIYVSGVKEENITVVGDATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSTVAVLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLALICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPVGLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of SrlA, SrlB and SrlE is involved in glucitol/sorbitol transport.  It can also use D-mannitol.
What are the official names of this protein?
PTS system glucitol/sorbitol-specific EIIB component, EII-Gut, Enzyme II-Gut, Glucitol/sorbitol-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOAC2_MYCTO
Sequence: MARASGASDYRSGELSHQDERGAAHMVDITEKATTKRTAVAAGILRTSAQVVALISTGGLPKGDALATARVAGIMAAKRTSDLIPLCHQLALTGVDVDFTVGQLDIEITATVRSTDRTGVEMEALTAVSVAALTLYDMIKAVDPGALIDDIRVLHKEGGRRGTWTRR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase 2, Molybdenum cofactor biosynthesis protein C 2.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RL30_CHLL2
Sequence: MSDKTIRIIQVRSVIGCTKKQKATIKALGLGRPNYQVEKQDNPCLRGQIRVVQHLVKVEEL
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PAXI1_DANRE
Sequence: MSEDDLKVPEELFKDVKFYVVGDIDQKVVQLLKSGKGKEVSYNALATHIIAEDGDNPEVGESREVFDLPVVKPSWVILSVKCGDLLPVTGFSPESGQVFFGVTACLPHLAEDLNALWAFITFYGGDCQLHFNKKCTHLVVPEPKGAKYECALRHNNIKIVTPEWILDSVKEKNRKDEMLYHPRLTLYDAPEEEGSEYENERSSRSEGSYSDRRSPHSRRSSPTSSRDASPAGRRSPSTKHERKSELMFDDSDDSSPEKEDRNLNWTPAEVLPPGPAKRRLQPGKETGLINLCANVPPVPGSFGPPDARMVGAGAGAGGGVPMGVERLEVMSEWNSAARTLRNITNNTDTQQPSRPSNVAHIIQSFSASSKGVVDHMGNQGQSGIPNQLLLKAQQQLPPEAQQQLLQQQQQQSHQLQQQQQQHQMAQQHPMMLPQVMQMHHHQQQQQHQPPPQQQQQQQNQQGFPQMPPQSHQFLQQQMHQQMYSQHQQQQQQQQQQQQQHAFPQQMRPQQLPRLPLQHQQQHVLQQQLQLQQQHRLQLQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQKQQQQQQQNQQQMHQQYLQQQQHFLQQQLQQQHMQQLQQQQQMQQQQQQHLQNQQPLQHQNQQVNPHQTQTMLQPPITSAQLFGHEPGHDIPEEGFLVGCIFAIADYPEQMADKQLLATWKRIIQLNGGTVDSALNRCTHLLCESQVSNTYLQALREGKRCVTAHWLNTVLKKKKMVPPHRTLHLPFSFPPGAKPCAQHIISVTGFVDSDRDDLKLMAYLAGARYTGYLCRSNTVLICKEPSGLKYEKAKEWRIPCVNAQWLCDILLGNFEALRQIQHSKYTQFNLPDPLAPNHHLVHNLLSAWRIPVKISPEALASLRLQLKQKQADVSVQPPSKRPKLEELPTPTKSFHLIQHLTSFSQALNLCRLSST
What is the function of this protein?
Involved in DNA damage response.  May function as transcriptional cofactor in TGF beta signaling.  Accentuates Smad2-dependent transcription (By similarity).
What are the official names of this protein?
PAX-interacting protein 1, PAX transactivation activation domain-interacting protein.
What are the subcellular locations of this protein?
Nucleus.