PharMolix/UniProtQA huggingface dataset:
Protein: AUR31_RANRN
Sequence: GLFDIVKKIAGHIAGSI
What is the function of this protein?
Has antimicrobial activity against L. lactis, L. innocua, M. luteus, S. aureus, S. epidermidis and S. uberis.  Probably acts by disturbing membrane functions with its amphipathic structure.  Shows anticancer activity.
What are the official names of this protein?
Aurein-3.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_MYCA1
Sequence: MAKSNKRRPAPEKPVKARKCVFCAKKDQAIDYKDTALLRTYISERGKIRARRVTGNCVQHQRDIAIAVKNAREVALLPFTSSAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: HIP_ALLWA
Sequence: SAPANAVSADDATAIALKYNQDATKSERVSAARPGLPPEEQHCANCQFMQADAAGATDEWKGCQLFPGKLINVNGWCASWTLKAG
What is the function of this protein?
Specific class of high-redox-potential 4Fe-4S ferredoxins.  Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria.
What are the official names of this protein?
High-potential iron-sulfur protein, HiPIP.
What is the protein family that this protein belongs to?
Belongs to the high-potential iron-sulfur protein (HiPIP) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SYG_CHLT2
Sequence: MSSQPLTLQAMMAAILNFWSEQGCIIHQGYDLEVGAGTFNPATFLQSLGPEPFRTAYIEPSRRPQDGRYGQHPNRLQKYHQLQVILKPVPENFLSLYLESLKVIGLNLVDHDIRFVHDDWENPTIGAWGLGWEVWLNGMEITQLTYFQAVGSKPLDAISGEITYGVERIAMYLQKKNSVYDVMWNGSLTYGDITQYAEQAWSQYNFETANTTMWLKHFDDFSAEALATLDQGLPLPAYDFVIKASHAFNMLDSRGVISVTERTRYIAKIRQLARAAADKYVAWRESLGFPLLKTPPSTPTVTPKKIPTICQPEDFLLEIGSEELPATFVPTGIQQLESLAKKLLADHGIAYKHLEVLGTPRRLALCIEGLSHVTIRPESEKKGPPLSLLFMTDGSVSPQGEQFFPSHGLSISHRSALDQPSAICRVRSINGTDYLFLVIPEERKETAAILVNELPQLIRSIRFPQKMTWDNGGVEYARPIRWLVALYGDQILPISLGFVSSGNTSWGHRQLDNRQLTIPSSNMYVDTLRSACVIVSQKERRAIIKQGLQNLTGDQIVAIAPEHLVDETVFLTEHPFVISAQFDPAFCSLPKELLIAEMIQHQRYFPTQNMQGEITNRFLIVCDNSPTDSIVEGNEKALAPRLTDGNFLFKQDLLTPLSSFVEKLKSVTYFESLGSLADKTSRLKLHLEEAYALLPLCAKEDIDTAIHYCKADLVSSVVNEFPELQGIMGRYYLQNASLSRAAALAIGEHLQHITLGSNISTTGALLSILDRIDNLLSCFILGLLPTSSHDPYALRRQSLEILTLLYTTQSSVDIEDLFARLIRHFPSSIPNTVWSPEEVLSKLNTFVWGRLRTILSSLGFDKEIIATVLTDNCPKNPLTIIQSAQSIQELKNTQILKTIAATHNRLKKILASLSFSVTEQMFSLQSAEDLLFKQALDRFVEETTALPISSKDYLHLLKELAQSTELFLDSVRVASDDESTRNQRIALLIAAQKCFGFYAWDVL
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BRUSU
Sequence: MNAPTTVADSVTVPVSLGDRSYDILIGKGLVERAGEEVAKRLKGVRVAIVTDENVAAVHLERLQASFARAGIDSTPVIVAPGEKSKSFATLETVTNAILAAKLERGDAVVALGGGVVGDLSGFVAGIVRRGMNFVQMPTSLLAQVDSSVGGKTGINTAHGKNLVGVFNQPQLVLADTQVLDTLSPREFRAGYAEVAKYGLIDRPDFFAWLEANWQEVFSGGAARTKAIAESCRSKAAVVARDERETGDRALLNLGHTFGHALESATGYDSSRLVHGEGVAIGMALAYRFSARMNLAGIEAAERVEAHLKAVGLPVSLAEVPGGLPPAEKLMDYIAQDKKVTRGTLTFILTHGIGQSFIAKDVPPAAVLEFLKERLAIA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_BRAHW
Sequence: MKSFLSDKAKSIEPYTPGEQPKDKNYIKLNTNESPYPPSPYVKKALIESNFDDLRLYPDPNVSDLKKEIAELYNINTNNIFIGNGSDEILAFCFMAFFNRGDKIYYPNITYSFYSVYSSLFDLNEVKIPLKDDFTIDINDYKNLDSGIFIANPNAPTGLLLTLDQLEEIIINNKDNIVIIDEAYIDFAAIESAYKLTKKYDNLLVVQTFSKSRSLAGIRLGFAIGNENLIQGLKNIKYSFNSYTINRLSIIAGIEAIKDNQYFKDTVNKVINTREKTKIKLKELGFNVLDSKSNFIFISHKNIFAEDLYLKLKDKGILVRYFKSDLINNYIRVTIGTDEEMDIFVEKIKYIIKN
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: SYDM_ARATH
Sequence: MSLLLRTLPLRPTRFLSATAISISNATNFFVVPKRTNPLPGTRRTFSSSPVAAASGDVVVKPVPSPPSVLRWVSRTELCGELSVNDVGKRVHLCGWVALHRVHGGLTFLNLRDHTGIVQVRTLPDEFPEAHGLINDMRLEYVVLVEGTVRSRPNESVNKKMKTGFVEVVAEHVEILNPVRTKLPFLVTTADENKDLIKEEIRLRFRCLDLRRQQMKNNIVLRHNVVKLIRRYLEDRHGFIEIETPILSRSTPEGARDYLVPSRIQSGTFYALPQSPQLFKQMLMVSGFDKYYQIARCFRDEDLRADRQPEFTQLDMEMAFMPMEDMLKLNEDLIRKVFSEIKGIQLPDPFPRLTYADAMDRYGSDRPDTRFDLELKDVSNVFTESSFRVFTEALESGGIIKVLCVPLGAKKYSNSALKKGDIYNEAMKSGAKGLPFLKVLDNGEIEGIAALVSSLDSAGKINFVKQCGAAPGDLILFGVGPVTSVNKTLDRLRLFVAHDMDLIDHSKHSILWVTDFPMFEWNEPEQRLEALHHPFTAPKPEDMDDLPSARALAYDMVYNGVEIGGGSLRIYKRDVQEKVLEIIGISPEEAESKFGYLLEALDMGAPPHGGIAYGLDRMVMMLGGASSIRDVIAFPKTTTAQCALTRTPSEVDPKQLQDLSIRTK
What is the function of this protein?
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.
What are the official names of this protein?
Aspartate--tRNA ligase, chloroplastic/mitochondrial, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: NUOB_CITK8
Sequence: MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEINKSVYMGKLEHALHDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LATS1_HUMAN
Sequence: MKRSEKPEGYRQMRPKTFPASNYTVSSRQMLQEIRESLRNLSKPSDAAKAEHNMSKMSTEDPRQVRNPPKFGTHHKALQEIRNSLLPFANETNSSRSTSEVNPQMLQDLQAAGFDEDMVIQALQKTNNRSIEAAIEFISKMSYQDPRREQMAAAAARPINASMKPGNVQQSVNRKQSWKGSKESLVPQRHGPPLGESVAYHSESPNSQTDVGRPLSGSGISAFVQAHPSNGQRVNPPPPPQVRSVTPPPPPRGQTPPPRGTTPPPPSWEPNSQTKRYSGNMEYVISRISPVPPGAWQEGYPPPPLNTSPMNPPNQGQRGISSVPVGRQPIIMQSSSKFNFPSGRPGMQNGTGQTDFMIHQNVVPAGTVNRQPPPPYPLTAANGQSPSALQTGGSAAPSSYTNGSIPQSMMVPNRNSHNMELYNISVPGLQTNWPQSSSAPAQSSPSSGHEIPTWQPNIPVRSNSFNNPLGNRASHSANSQPSATTVTAITPAPIQQPVKSMRVLKPELQTALAPTHPSWIPQPIQTVQPSPFPEGTASNVTVMPPVAEAPNYQGPPPPYPKHLLHQNPSVPPYESISKPSKEDQPSLPKEDESEKSYENVDSGDKEKKQITTSPITVRKNKKDEERRESRIQSYSPQAFKFFMEQHVENVLKSHQQRLHRKKQLENEMMRVGLSQDAQDQMRKMLCQKESNYIRLKRAKMDKSMFVKIKTLGIGAFGEVCLARKVDTKALYATKTLRKKDVLLRNQVAHVKAERDILAEADNEWVVRLYYSFQDKDNLYFVMDYIPGGDMMSLLIRMGIFPESLARFYIAELTCAVESVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCTGFRWTHDSKYYQSGDHPRQDSMDFSNEWGDPSSCRCGDRLKPLERRAARQHQRCLAHSLVGTPNYIAPEVLLRTGYTQLCDWWSVGVILFEMLVGQPPFLAQTPLETQMKVINWQTSLHIPPQAKLSPEASDLIIKLCRGPEDRLGKNGADEIKAHPFFKTIDFSSDLRQQSASYIPKITHPTDTSNFDPVDPDKLWSDDNEEENVNDTLNGWYKNGKHPEHAFYEFTFRRFFDDNGYPYNYPKPIEYEYINSQGSEQQSDEDDQNTGSEIKNRDLVYV
What is the function of this protein?
Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.  Phosphorylation of YAP1 by LATS1 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration.  Acts as a tumor suppressor which plays a critical role in maintenance of ploidy through its actions in both mitotic progression and the G1 tetraploidy checkpoint.  Negatively regulates G2/M transition by down-regulating CDK1 kinase activity.  Involved in the control of p53 expression.  Affects cytokinesis by regulating actin polymerization through negative modulation of LIMK1.  May also play a role in endocrine function.  Plays a role in mammary gland epithelial cell differentiation, both through the Hippo signaling pathway and the intracellular estrogen receptor signaling pathway by promoting the degradation of ESR1 (PubMed:28068668).
What are the official names of this protein?
Serine/threonine-protein kinase LATS1, Large tumor suppressor homolog 1, WARTS protein kinase, h-warts.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to the centrosomes throughout interphase but migrates to the mitotic apparatus, including spindle pole bodies, mitotic spindle, and midbody, during mitosis.
Protein: RS17_SHEB2
Sequence: MSDKIRTLQGRVTSNKMDKSITVAIERQVKHPIYGKYIKRTTKIHAHDETNQCNEGDLVAIRECRPLSKTKSWTLVEVVSKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: TYW2_METJA
Sequence: MGIKYQKIGDVVIVKKELSEDEIREIVKRTKCKAILLYTTQITGEFRTPHVKILYGKETETIHKEYGCLFKLDVAKIMWSQGNIEERKRMAFISNENEVVVDMFAGIGYFTIPLAKYSKPKLVYAIEKNPTAYHYLCENIKLNKLNNVIPILADNRDVELKDVADRVIMGYVHKTHKFLDKTFEFLKDRGVIHYHETVAEKIMYERPIERLKFYAEKNGYKLIDYEVRKIKKYAPGVWHVVVDAKFERI
What is the function of this protein?
S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway.  Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe).
What are the official names of this protein?
tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase, MjTYW2, tRNA wyosine derivatives biosynthesis protein Taw2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS51_NITWN
Sequence: MTAAIIDYGSGNLHSAAKALECAARGMEGLQRIVVTRDPDVVFRADRVVLPGVGAFADCRRGLDALDGMVQALTEVVRDKARPFLGICVGMQLMATRGKEHVTTDGLGWIAGDVERISPRDESLKIPHMGWNTLDPAREHPVLEGLPLGPKGRHAYFVHSYHLNAANETDVLARADYGGPVTAIVGKDTAIGTQFHPEKSQRFGLALIANFLRWKP
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH 1, IGP synthase glutaminase subunit 1, IGP synthase subunit HisH 1, ImGP synthase subunit HisH 1, IGPS subunit HisH 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOB1_ARATH
Sequence: MDPKPTSMWSSIVKKDPPSKPPVNDGAPAAILGMVGNCKSTKGISIAVVDANAIIEGRQSLTNFADKFVTVPEVLSEIRDPASRRRLAFIPFTIDTMEPSPESLSKVIKFARATGDLQSLSDVDLKLIALSYTLEAQVYGTKNLRDVPPPIQTVRVKRLPEKDLPGWGSNVANLEEWEALENETEEKSNANSKILPLKDLNMNIIASDNVSEVGSVVSHTENHEEDVQEGGKKHRRYPPKKTEIKLEGKMVVEGVDASQGQYDDDDDASDWRPAVSRSTHSKYLRRKARWEHYNALAEQEIQKDQEADKARHTKEANETHAKDSGKNGEDISSILKDMRLEEESLRALQEETEETNAEATLINGEDDIDHDIEVEAEGIDVANQALENLEIASEAEDTFEASSIGDDGSSEQSWSLRALSESSVACITGDYAMQNVILQMGLRLLAPGGMQIRQLHRWILKCHACYTVTPEIGRIFCPKCGNGGTLRKVAVTIGANGAIIAACKPRITLRGTQYSIPMPKGGREAITKNLILREDQLPQKLLHPRTKKKASKPGDEYFVSDDVFLNHHSDRKAPLQPPVRKAMSVFSQKRNPNDNHYSRSMH
What is the function of this protein?
Essential protein required during embryogenesis and pollen development (PubMed:23382868).  Endonuclease cleaving pre-rRNA at the 3' end of the mature 18S rRNA (D-site); cleaves 20S pre-rRNA in the cytoplasm (PubMed:23382868).  Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (PubMed:23382868).
What are the official names of this protein?
RNA-binding NOB1-like protein, AtNob1.
What is the protein family that this protein belongs to?
Belongs to the NOB1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Cytoplasm.
Protein: RHAT_SHIFL
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPDFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNTGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL32_STRPZ
Sequence: MAVPARHTSKAKKNKRRTHYKLTAPSVQFDETTGDYSRSHRVSLKGYYKGRKIAKANEAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: VP4_ROTHT
Sequence: MASLIYRQLLTNSYTVELSDEINTIGSEKSQNITINPGPFAQTNYAPVTWSHGEVNDSTTIEPVLDGPYQPTSFKPPSDYWILLNPTNQQVVLEGTNKTDIWIALLLVEPNVTNQSRQYTLFGETKQITIENNTNKWKFFEMFRSNVSSEFQHKRTLTSDTKLAGFLKHYNSVWTFHGETPHATTDYSSTSNLSEVETTIHVEFYIISRSQESKCVEYINTGLPPMQNTRNIVPVALSSRSVTYQRAQVSEDIIISKTSLWKEMQYNRDIIIRFKFNNSIIKLGGLGYKWSEISFKAANYQYNYLRDGEQVTAHTTCSVNGVNNFSYNGGLLPTHFSISRYEVIKENSYVYVDYWDDSQAFRNMVYVRSLAANLNSVKCSGGNYNFQMPVGAWPVMSGGAVSLHFAGVTLSTQFTDFVSLNSLRFRFSLTVEEPPFSILRTRVSGLYGLPASNPNSGHEYYEIAGRFSLISLVPSNDDYQTPIMNSITVRQDLERQLGDLREEFNSLSQEIAITQLIDLALLPLDMFSMFSGIKSTIDAAKSMATKVMKKFKRSGLATSISELTGSLSNAASSVSRSSSIRSNISSISEWTDVSEQIAGSSDSVRNISTQTSAISRRLRLREITTQTEGMNDIDISAAVLKTKIDRSTHIRPDTLPDIITESSEKFIPKRAYRVLKDDEVMEADVDGKFFAYKVDTFEEVPFDVDKFVDLVTDSPVISAIIDFKTLKNLNDNYGITRSQALDLIRSDPRVLRDFINQNNPIIKNRIEQLILQCRL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: RFC5_DICDI
Sequence: MEIDMADKTNKFKTDIERKQFESLPWVEKYRPKNLDDLIAHEDITQTITKLIDNNTLPHLLFYGPPGTGKTSTIQAIARKLYGDNYSRMVLELNASDDRGIDVVREQIKTFASSMFFFNTTVPYKLIILDEADSMTNIAQTALRRVIEKYTKTTRFCIVCNYVIKIIPALQSRCTRFRFSPLPTPPTEIRLKEIIEKENVKVDSKAMNAVLELGCGDMRKCLNILQSVSMSSIDNNITEEAIYKCTGYPMPSDIELMVDWLLNSDYEEAFQNISDLKKKKGLSLNDIIATLQKFVVQIDLDNVILCKLLSHLSDIEYNLSIGSSEKLQLGSLVGCFQLSRDDELLHN
What is the function of this protein?
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1.
What are the official names of this protein?
Probable replication factor C subunit 5, Activator 1 subunit 5.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRG_RHOPB
Sequence: MARYIFITGGVVSSLGKGLASAALGALLQSRGYKVRLRKLDPYLNLDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPATKADNITTGRIYQDILTKERRGDYLGATIQVIPHVTNAIKEFILDSNDAYDFVLCEIGGTVGDIEGLPFFEAIRQIKNDLPRGEAIYVHLTLLPYIPSAGELKTKPTQHSVKELRSIGIQPDILLCRTDREIPKEERRKLGLFCNVRESAVIEARDVDNIYAVPEAYHAAGLDDEVLAAFGIAPKAEPDMISWNVINERIRNPEGQVTIAIVGKYTGMKDAYKSLSEALSHGGIANKVKVNLDWIESEVFENEDPAPFLEHVNGILVPGGFGQRGAEGKIRAAQFARERNVPYFGICFGMQMAVIEAARNLAGIAAANSTEFGPTKEPLVGLMTEWLRGNEREQRSHAGDLGGTMRLGAYPAMLQRGSRVSEVYGGALEISERHRHRYEVNTAYKDRLEQHGLRFSGLSPDGVLPEIVEYEDHPWFIGVQFHPELKSRPFEPHPLFASFVQAAVVQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RL11_CUPNH
Sequence: MAKKIIGFIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAQTQGMEPGLPVPVVITAFADKSFTFVMKSPPATVLIKKAAGITKGSPKPHTDKVGKITRAQAEEIAKAKNADLTAADLDAAVRTIAGSARSMGITVEGL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: LDHB_MACFA
Sequence: MATLKEKLIAPVAEEEATVPNNKITVVGVGQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVADKDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLKGYTNWAIGLSVADLIESMLKNLSRIHPVSTMVKGMYGIENEVFLSLPCILNARGLTSVINQKLKDDEVAQLKKSADTLWDIQKDLKDL
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase B chain, LDH-B.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
Protein: COAX_BACFN
Sequence: MNLIIDIGNTVAKVALFDRTSMVEVVYDSNQSLDSLEAVCNKYDVRKAIVATVIDLNECVLAQLNKLPVPVLWLDSHTPLPVINLYETPETLGYDRMAAVVAAHDQFPGKDILVIDAGTCITYEFVDSLGQYHGGNISPGLWMRLKALHQFTGRLPLVHAEGRMPDMGKDTETAIRAGVKKGIEYEITGYIAAMKHKYPELLVFLTGGDDFSFDTKLKSVIFADRFLVLKGLNRILNYNNGRI
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CF052_HUMAN
Sequence: MAQPESSADFGIAQQNNYYCYWQSLPSAIRVKQEFQPSQSYRYGNWYARQHGSYLLSGYSYGCAVDGNGKDCFSAHETPEHTAGTLVMPKETTPLAENQDEDPLEDPHLHLNIEESNQEFMVKSEELYDSLMNCHWQPLDTVHSEIPDETPK
What are the official names of this protein?
Putative uncharacterized protein C6orf52.
Protein: AAPP_RHIL3
Sequence: MAEAPAKKLTVSATEVAVEIVNMNKWYGDFHVLRDINLKVMRGERIVIAGPSGSGKSTMIRCINRLEEHQKGKIVVDGTELTNDLKKIDEVRREVGMVFQHFNLFPHLTILENCTLAPIWVRKMPKKQAEEVAMHFLKRVKIPEQANKYPGQLSGGQQQRVAIARSLCMNPKIMLFDEPTSALDPEMIKEVLDTMVGLAEEGMTMLCVTHEMGFARQVANRVIFMDQGQIVEQNEPAAFFDNPQHERTKLFLSQILH
What is the function of this protein?
Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as the efflux of these amino acids.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
General L-amino acid transport ATP-binding protein AapP.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: HYPE_ECOLI
Sequence: MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAVDKLFINTAGMGAIPANIHWGAQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGCGIELSEAALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPRIC
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Along with HypF, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases.  HypE catalyzes the ATP-dependent dehydration of the carboxamido group attached to its C-terminal cysteine to a cyano group (PubMed:12586941, PubMed:15291820).  The cyano group is then transferred from HypE to the HypC-HypD complex or the HybG-HypD complex (PubMed:15504408).
What are the official names of this protein?
Carbamoyl dehydratase HypE, Hydrogenase maturation factor HypE.
What is the protein family that this protein belongs to?
Belongs to the HypE family.
Protein: NUOK_HELHP
Sequence: MISLNHYLLLCVILFCIGLFGILRRSNILMLFFSTEILLNAINIGFVAIGSYLNDLNGEIFALFIIAIAASEIAVGLGLVVIWYKKHRTLDITTLQNLKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.