PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_PSEFS
Sequence: MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTHDGAETDLDLGHYERFIRTTMTQNNNFTTGRVYEHVLRKERRGDYLGATIQVIPHITDEIKRRIIKGAGDADVAMVEIGGTVGDIESQPFLEAIRQLRFEVGAKRAMLMHLTLVPYIATAGETKTKPTQHSVKELRSIGLQPDVLVCRSDHPIDISSRRKIAQFTNVEERAVIALEDADTIYKIPGILHSQGLDDFVVERFGLQCNGADLSEWEAVVDAKLNPEHEVTIAMVGKYMELLDAYKSLIEAMSHAGISNRTKVNLRYIDSEDIENQGTALLEGVDAILVPGGFGLRGVEGKITAVQYARENKVPYLGICLGMQVAVIEFARNVLGWKDANSTEFDSKSGHPVVGLITEWEDATGAVETRTEASDLGGTMRLGAQDCLLEQGSLVHDCYGKDVIVERHRHRYEVNNNLLPQIKEAGLKISGRSGDGALVEVVEAPDHPWFVACQFHPEFTSTPRDGHPLFSGFVKAALTQHQKKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CATIN_TOXGV
Sequence: MGKKRRKHDGSGSSRSPSPDRIREARNPSQAEVAGFRAPPSGKPAMTVKQLREERQKLLHEHFGYSNTNNPFGDRLLAEPFVWKKKNQLLQAAGQKGKTTVAALIHSSKSKVQEIENVKRRREEREKEEELMQQQREELQREKEREHYEEYAQKEELFHRSNQLKKTEIRLEQNRAQLIDLIVKGLRIIKGERFEKMDVLPGPPHEVLETYKNEPVTVAMLEDLIADVKLHIDVDTTVVDADFQDFWKSLLVLAREALERAKKRKDVLDQLARNSSPQMAAEAAAQLADTVCPQIRDADTGIVLSVAHEIEGLLGGKSAAELDELEAQIRSKFEEEDIDVAYWEGILNKIPSFRARAVCLQTWHMMTQSAADAEREMAREKALKEEEEAKAARAKGEELEGLLLEEADARKLARAQQIKQDAIKVARSVEKDVNPNADGSFSPELEPYDEGEVPPPVRGPYSPQLWPFDEFRHAEILAPDDDEDRRAILKKTLIQKERLKRAGLEEDPEPTPEAAENDASLDVLDPAAKVTTYEEFVKKEKKNLEADEEVMASSSEHKLTMHYTWEEKYRPRKPRFFNRVKTGYSWNKYNTTHYDHDNPPPKVVQGYKFNIFYPDLIDKTKAPTWFLEPSDTPDTVIIRFHAGPPYEDIAFKILNQEWQLERFRGFRNVFDRGIMQLYFSFKRYIYRR
What is the function of this protein?
Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (By similarity).  Involved in the regulation of G1 progression and stage differentiation of tachyzoites.  May play a role in gene expression.
What are the official names of this protein?
Splicing factor Cactin.
What is the protein family that this protein belongs to?
Belongs to the CACTIN family.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes in the nucleus throughout the entire tachyzoite cell cycle.
Protein: SERP1_MOUSE
Sequence: MVAKQRIRMANEKHSKNITQRGNVAKTSRNAPEEKASVGPWLLALFIFVVCGSAIFQIIQSIRMGM
What is the function of this protein?
Interacts with target proteins during their translocation into the lumen of the endoplasmic reticulum.  Protects unfolded target proteins against degradation during ER stress.  May facilitate glycosylation of target proteins after termination of ER stress.  May modulate the use of N-glycosylation sites on target proteins (By similarity).
What are the official names of this protein?
Stress-associated endoplasmic reticulum protein 1, Ribosome-attached membrane protein 4.
What is the protein family that this protein belongs to?
Belongs to the RAMP4 family.
Protein: CYSJ_YERPN
Sequence: MTTQAPPTSLLPLSPEQLARLQAAVGEFSPTQMAWLSGYFWGMVNQQPGAVASPAVAAPPPVTVTLISASQTGNARRLAEQLRDDLLAAQLSVNLVNAGDYKFKQIAQERLLVVVASTQGEGEPAEEAVALHKFLFSKKAPKLSETAFAVFGLGDTSYEHFCQAGKDFDSKLAELGAQRLLDRVDADVEYQVQAQQWRQQVVATLQAKVPAQSTAPTQFIAPTQSTTPAAAAITSGGTTTVSPYSKTAPLTAQLSVQQKVTGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWFDNDPALVEELLALLWLKGDEPVSIDGQNMPLAQALLSHLELTQNTTLIVDKYAALSRDETLIALLADKPALQLYAKNTPFVDMVRQAPSDLNADQLVGLLRPLTPRLYSIASSQAETENEVHITVGVVRYDIDGRARSGGASGYLADRLEVDGDIRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQREVDGASGKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQAHKIYVQDKLREQGAELWNWIQQGAHIYVCGDANRMAKDVEQVLLDVVALHGAMDAEQADEYLSELRQARRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: LACC_STRP8
Sequence: MILTVTLNPAIDVSYPLDELKCDTVNRVVDVTKTPGGKGLNVCRVLNDFGETVKATGCIGGESGDFIINHLPDSILSRFYKISGDTRTCIAILHEGNQTEILEKGPLLSVEEIDGFTHHFKYLLNDVDVVTLSGSLPAGMPDDYYQKLIGIANLNGKKTVLDCSGNALEAVLKGDSKPTVIKPNLEELSQLLGKEMTKDFEALKEVLQDELFEGIEWIIVSLGADGVFAKHNDTFYNVDIPKIEIVSAVGSGDSTVAGIASGLANDEDDRALLTKANVLGMLNAQEKTTGHVNMANYDKLYQSIKVKEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: MATK_LILRE
Sequence: MEEVQEYLKKDRSPQQHFLYPLLLQEYIYTLAHDDSLNGSIFYEPIEFIGYDNKFSLVLVKRLIIRMYQQNFLIYLVNDSNQNRFGGHSNYFYSHFFYSQMVSKGFSVIVEIPFSLRLVSSSEEKEIPKSQNLGSIHSIFPFLEDKLSHLNNVSDILIPHPIHFEILVQILQCWIQDVPSLHLLRFFLHKYQNLNKTIQSNKTIYVFSKENKRLFWFLYNSYVSECEFLLVFFHKQSCYLRSTSSGAFLERSHFYGKMEHIIIVCCNNFQKTLWPVKDPLIHYVRYQGKAILASRGTHLLMKKWRYYFVNFWQYYFHFWSQPYRMHINSLLNYSFYFMGYLLGVLINPYAVKNQMLENSFLIDTVINKFDTIIPIIPLIGSLSKAKFCTFSGHPISKPIWADLLDFDIIDRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSGGXXLARKHKSTXVPLLQRLGSGLLEEFFTEEXQVLSFFFPKTTLFTLHGSHRERIWSLDIIRINDLVNN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YFAT_ECOLI
Sequence: MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSSQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
What are the official names of this protein?
Uncharacterized protein YfaT.
What is the protein family that this protein belongs to?
To P.aeruginosa PA4490 and T.maritima TM0986.
Protein: SLD2_YEAST
Sequence: MYSFELDKLKIELKTWEHDFIDKNKREPTRDDIKSLRTVRQMYKQYSTLKKKQSLQRQKVDTQESVELPAHKKDHDEVVEIGPTPQVYGKAISIFDMNLSPIKPIYMTFTNNIDVNNDNSKTISNESSPRKTILLKSSPADRTLVAEPISSVKRQLNFQMLNASSTRTPTSSPCKNRNGKLVEIKKCSPTINPPLESGKPSGYYGPNSPLKLDEENIHLNISLNSSTKRRLQIAYPSLQKTPSKDQADISTSFSPSPLIRRPLTKSLIELAREHTEIVKEFGVLQEEDIEEEEEGEEGENGYDEKNHEDDFGLEDELIRPKVVKDIFQEDDDNDDSQAREDTFIRKRPKRRKVIRRLRDNDPETETAGFERDVHKELVKLKRRKVAEFLGSTSQISDTEFEHDPEASSGVVSSEQKPTAKRKGRKKYNLVSNNFRRLKLPKKNRFSNGRWGRR
What is the function of this protein?
Has a role in the initiation of DNA replication.  Required at S-phase checkpoint.  Also required for the proper activation of RAD53 in response to DNA damage and replication blocks.
What are the official names of this protein?
DNA replication regulator SLD2, DNA replication and checkpoint protein 1.
What is the protein family that this protein belongs to?
Belongs to the SLD2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPS_PSEAE
Sequence: MEKTRKDVCVPRHVAIIMDGNNRWAKKRLLPGVAGHKAGVDAVRAVIEVCAEAGVEVLTLFAFSSENWQRPADEVSALMELFLVALRREVRKLDENGIRLRIIGDRTRFHPELQAAMREAEAATAGNTRFLLQVAANYGGQWDIVQAAQRLAREVQGGHLAADDISAELLQGCLVTGDQPLPDLCIRTGGEHRISNFLLWQLAYAELYFSDLFWPDFKHAAMRAALADFSKRQRRFGKTSEQVEAEARPSC
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: TP4AP_HUMAN
Sequence: MAAAPVAAGSGAGRGRRSAATVAAWGGWGGRPRPGNILLQLRQGQLTGRGLVRAVQFTETFLTERDKQSKWSGIPQLLLKLHTTSHLHSDFVECQNILKEISPLLSMEAMAFVTEERKLTQETTYPNTYIFDLFGGVDLLVEILMRPTISIRGQKLKISDEMSKDCLSILYNTCVCTEGVTKRLAEKNDFVIFLFTLMTSKKTFLQTATLIEDILGVKKEMIRLDEVPNLSSLVSNFDQQQLANFCRILAVTISEMDTGNDDKHTLLAKNAQQKKSLSLGPSAAEINQAALLSIPGFVERLCKLATRKVSESTGTASFLQELEEWYTWLDNALVLDALMRVANEESEHNQASIVFPPPGASEENGLPHTSARTQLPQSMKIMHEIMYKLEVLYVLCVLLMGRQRNQVHRMIAEFKLIPGLNNLFDKLIWRKHSASALVLHGHNQNCDCSPDITLKIQFLRLLQSFSDHHENKYLLLNNQELNELSAISLKANIPEVEAVLNTDRSLVCDGKRGLLTRLLQVMKKEPAESSFRFWQARAVESFLRGTTSYADQMFLLKRGLLEHILYCIVDSECKSRDVLQSYFDLLGELMKFNVDAFKRFNKYINTDAKFQVFLKQINSSLVDSNMLVRCVTLSLDRFENQVDMKVAEVLSECRLLAYISQVPTQMSFLFRLINIIHVQTLTQENVSCLNTSLVILMLARRKERLPLYLRLLQRMEHSKKYPGFLLNNFHNLLRFWQQHYLHKDKDSTCLENSSCISFSYWKETVSILLNPDRQSPSALVSYIEEPYMDIDRDFTEE
What is the function of this protein?
Substrate-recognition component of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control (PubMed:20551172, PubMed:29779948).  The DCX(TRPC4AP) complex specifically mediates the polyubiquitination and subsequent degradation of MYC as part of the DesCEND (destruction via C-end degrons) pathway (PubMed:20551172, PubMed:29779948).  The DesCEND (destruction via C-end degrons) pathway recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (PubMed:29779948).  The DCX(TRPC4AP) complex specifically recognizes proteins with an arginine at the minus 3 position (R-3 motif) at the C-terminus, such as MYC, leading to their ubiquitination and degradation (PubMed:29779948).  Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome (By similarity).  Involved in JNK activation via its interaction with TRAF2 (By similarity).  Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1 (By similarity).
What are the official names of this protein?
Short transient receptor potential channel 4-associated protein, Trp4-associated protein, Trpc4-associated protein, Protein TAP1, TNF-receptor ubiquitous scaffolding/signaling protein, Protein TRUSS.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: EX7S_BURO1
Sequence: MAKTASPGATPPGNGTEPLPDNYEMALAELETLVARMEGGALSLEDSLAAYRRGATLVAFCQQQLEKVEQQVRVLDGATLKPLSSGTAATDGEDDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
Protein: NANK_SALPB
Sequence: MTTLAIDIGGTKLAAALIDNNLRISQRRELPTPASKTPDALREALKALVEPLRAEARQVAIASTGIIQEGMLLALNPHNLGGLLHFPLIQTLETIAGLPTLAVNDAQAAAWAEYHALPDDIRDMVFITVSTGVGGGVVCDGKLLTGKGGLAGHLGHTLADPHGPVCGCGRVGCVEAIASGRGMAAAARDDLAGCDAKTLFIRAGEGHQQARHLVSQSAQVIARMIADVKATTDCQCVVIGGSVGLAEGYLEQVRAFLMQEPAPYHVALNAARYRHDAGLLGAALLAQGDTL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: EX7L_PARL1
Sequence: MPPSDTQSPAANNAHEFSVSEISFALKKTVEETFGHVRVRGEITGYRGPHSSGHCYFGLKDDKARMDAVIWKGNFGKLRFKPEEGMEVIATGKLTTYPGSSKYQIVIDHLEPAGVGALMALLEERRKKLAAEGLFAAERKRALPFLPEVIGVVTSPTGAVIRDILHRLQDRFPRHVIVWPVRVQGETSAAEVAAAIRGFNAMEKGGKTPRPDLLIIARGGGSIEDLWSFNEEIVVRAAAESAIPLISAIGHETDTTLIDFASDRRAPTPTAAAEMAVPVRAELLADVRDKGSRLIRCEARAIESYRTQLGGLARGLPKLQDLVALPRQRFDTAADRLGRALIRAAEVKRARLSRVEGRLSDRPIRLRIANERKGLPQLLQRLTRAETRRVADLARSLDGSTKLLESYSYHGVLKRGYAVVRDETGKPIRAGAGQTAGARIEIEFAEDRLDAVVAPGGTVAPRKAPPKKPGGGQGSLL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYSI_BOVIN
Sequence: MKAVLILGLLLLSVTVQGKKFEKCELARTLRRYGLDGYKGVSLANWMCLTYGESRYNTRVTNYNPGSKSTDYGIFQINSKWWCNDGKTPKAVNGCGVSCSAMLKDDITQAVACAKTIVSRQGITAWVAWKNKCRNRDVSSYIRGCKL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, intestinal isozyme, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: DSBB_ECOUT
Sequence: MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLCIYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFATCDFMARFPEWLPLDKWVPQVFVASGDCAERQWEFLGLEMPQWLLGIFIAYLIVAVLVVISQPFKAKKRDLFGR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: P20D1_ASPCL
Sequence: MRSLTLLLSLSTALRSVAAPHPASPQGQIPLGGIPSASTSEVGIGIGIGIEEDPFPPAAGSGHNDLEDVINASPLLSFHRDLVSIESISGHEARAAAFVADFLEAHNFTVVKQPVAGDRVNIFASPRAHAHSRPEILLTSHLDTVPPFIPYSLHRNDSRPTDRQLIRIAGRGAVDAKASVAAQIFAALDILHADPSAPLGLLFVVGEEVGGDGMKAFSHDPRLNPAPSRFHTVIFGEPTDFALVAGHKGMLGFEVLASGRPAHSGYPWLGRSAVSAILPALRRVDALGHIPVHHGGLPASHKYGRTTLNIGVLEGGVATNVVPAAARADVAVRLAAGSVDDARAIIAAAVADATHRDPAVVVDFSRHLEAYPPQDLDVDVPGFEITTVNYGTDVPNLHLHPRPDGPVKRYLYGPGSIFVAHGENEGLTVGALEEAVGGYKKLVQAALERTRA
What are the official names of this protein?
Probable carboxypeptidase ACLA_088580, Peptidase M20 domain-containing protein ACLA_088580.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Secreted.
Protein: RISB_PARPJ
Sequence: MEIGQYQPNLDGDGLRIGIVQARFNEPVCNGLADSCIEELERLGVTGEDVLLVTVPGALEIPLALQKLAESAQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFGIPVANAVLTTENDEQAVARMTEKGRDAARVAVEMANLAVALEQLGGDDEEEDEEEEEA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RNP2_METKA
Sequence: MRVRLSSALRPRWRYVTFKVWSERVEALDFGGMKDLVVRALLSVLGPTGTGRIGPWLVRSYRDLNAGILRVRRGQEEEARAALSLYRRDPKLGRVFIEVLGTSGTIKGAERYLSRIPKWDRERVGNREFVLYENGEVDVVEDGRIVAFASFECPLPEENRG
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOA_THUAL
Sequence: MSILKIHAREIFDSRGNPTVEVDLYTKKGLFRAAVPSGASTGIYEALELRDNDKTRYMGKGVKRAVKYINEFLAPALCNQDVTVIEQEKIDKLMLDMDGTENKYKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKDAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALKLLKNAIGKAGYTDKIVIGMDVAASEFYKGGKYDLDFKSPDDPSRYIPSDKLADLYKGFVKDYPVVSIEDPFDQDDWEAWSKFTASTSIQVVGDDLTVTNPKRIAKGVAEKSCNCLLLKVNQIGSVTESLQACKMAQSSGWGVMVSHRSGETEDTLISDLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGAKAKFAGKNFRHPI
What is the function of this protein?
Multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses.
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 1.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBC1_HUMAN
Sequence: MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQALNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQKQQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQFRYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANANKAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKGMTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERELCAVFQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNTSSR
What are the official names of this protein?
RIB43A-like with coiled-coils protein 1.
What is the protein family that this protein belongs to?
Belongs to the RIB43A family.
Protein: ADEC_BRUSU
Sequence: MRHCDSFCELIPMKGCEAMLEWMIDQGAGREPADIVLKGGRFLDLITGELVESDIAICEDRIVGTFGTYRGKHEIDVSGRIVVPGFIDTHLHIESSQVTPHEFDRCVLPQGVTTAICDPHEIANVLGAEGIRFFLDSALETVMDIRVQLSSCVPATHMETSGVELLIDDLLPFADHPKVIGLAEFMNFPGVLAKDPECMAKLRAFQGRHIDGHAPLLRGLDLNGYIAAGIRTEHEATNAEEALEKLRKGMYVLVREGSVSKDLKALMPIITERHAQFLALCTDDRNPLDIADQGHLDYLIRTAIAGGVEPLAIYRAASVSAARAFGLFDRGLVAPGQRADLVVVDSLEGCHAEIVLSAGRVVSEALFAARKPVAEVGRNSVKAPRVTASNFRSQSNSGKTRAIGIVPGKIITQNLEFDLKVGPNGVEPDLERDVVKVAVIERHGKNGNIATGFVHGFGLKAGAIASTVSHDSHNICVVGASDEDIATAANRLGEIEGGFVVVRDGKVLAEMPLPIAGLMSTEPYETVREALRKLRHAAEDLGSVLEEPFLQLAFIALPVIPHLKITDRGLVDVDKFEFVGN
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: GRPE_STRA5
Sequence: MAVFNKLFKRRHSVSEEIKKDDLQEEVEATETEETVEEVIEEIPEKSELELANERADEFENKYLRAHAEMQNIQRRSSEERQQLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKGLEMTRDSLIQALKEEGVEEVEVDSFDHNFHMAVQTLPADDEHPADSIAEVFQKGYKLHERLLRPAMVVVYN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_HALLT
Sequence: MSLSEPDHELVVAELGREPTAAEVALFENLWSEHCAYRSSRPLLSAFESEGDQVVVGPGDDAAVLALPEPDAADTPAAERDADDYGDQYVTFGVESHNHPSFVDPVDGAATGVGGIVRDTMSMGAYPIALLDSLYFGGFDRERSRYLFEGVVEGISHYGNCIGVPTVGGSVAFHDGYEGNPLVNVACVGLTNEDRLVTATAQEPGNTLMLVGNGTGRDGLGGASFASEDLAEDAETEDRPAVQVGDPYAEKRLIECNEALVDEDLVLSARDLGAAGLGGASSELVAKGGLGARLDLDSVHQREPNMNAMEILLAESQERMCYEVAPEDVARVEALAERFDLGCSVIGEVTDGNYVCEFAGAGKGEDDADDSDAESEVVVDVDAEYLADGAPMNDLASESPTQPDRDLPDPEPSLDEAVESVVSAPSTASKRWVYRQYDHEVGVRTAMKPGDDAAIMAIRETASTDAADLAPADQGVGLALSSGANPNWTETDPYEGARAVALENATNLAAKGAVPLAAVDCLNGGNPEKPEVYGGFKGIVDGLADACADLDAPVVGGNVSLYNDSVEGPIPPTPTLALIGTRKGYNAPPAALDADSAGDSELLLIGAGGADGGALGGSEYLAQAGGTDRFPTLPDTETKSLADRVASLAAVARHESTFATHDVSDGGLAVALAELVTDAAGADVTLPDRVAVFEETPGRLVVQTTDPEAVAELAGELPVLRLGEVTTDGALSLSVGDDETAFDADTIRELRGVIDRELA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RB11A_MOUSE
Sequence: MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPPTTENKPKVQCCQNI
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion.  The small Rab GTPase RAB11A regulates endocytic recycling.  Acts as a major regulator of membrane delivery during cytokinesis.  Together with MYO5B and RAB8A participates in epithelial cell polarization.  Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis.  Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells.  Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane.  Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane.  Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes (By similarity).  May also play a role in melanosome transport and release from melanocytes (PubMed:21291502).
What are the official names of this protein?
Ras-related protein Rab-11A, Rab-11.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Recycling endosome membrane; Lipid-anchor. Cleavage furrow. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle membrane. Note=Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Localizes to the cleavage furrow. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and lumenogenesis.