PharMolix/UniProtQA huggingface dataset:
Protein: Y1957_STAAC
Sequence: MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPLAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
What are the official names of this protein?
Uncharacterized RNA methyltransferase SACOL1957.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: Y2F4_ENCCU
Sequence: MRVWLVCMVGLLGGLHGSNVEESEDMKKVRKIFEKAFSRKLYDSEVERIRKLEKELCLDTRVMIPFIFHGDRVVALPTTRYQDVDKSEKKYVEKVVVQLRWLVWRLMAWVYVPGGSSWIRDLINEVFEATVSRDPDPVSLYKGARRRSGIRLMDLVMKVFKQNVSMVSEFGQRLARSAEDRIQGIPGSLSPEERKKEEEMLRKIKEHGERLCTKERQEEMVRAQEIICDVCAYVWERDEDRMSFIMEVYSRHLCLKIVMPYTDIEVPLISYIDHHKLVSTDEKYKSMNIMAEVFKQAFIEHKGIDDESINNAVREVRERKRLEEMREMEERKRREEERAKNEEELLRMVEREKREESKGRGKKKGGKRGAGEAKEESKEEDGKEEEGVEAEEEESAEVPLVETAVGGARRKKSLKGKRKGDGHHYKIHSRVLRWKRSAEKIKRELDKGSEERWKNRSIEEIKEQKKVHDIVEVSELIKSKECDRFFFRTGKYMKGGSERWKMVANGILEEGGEKKVGKVEVGLFKGERGESVVYHLMFRPTETERAGMVGGSSFGKGDDVDEIKKEESSDMSGFRYPPGVRCEMTSNGNEFRIEYRNPKNTSEVLRTLTILRIPEI
What are the official names of this protein?
UPF0329 protein ECU02_1540.
What is the protein family that this protein belongs to?
Belongs to the UPF0329 family.
Protein: TAT_HV2D1
Sequence: METPLKEPESSLESYNEPSSCTSERDVTAQERAKQGEELLAQLHRPLEACTNSCYCKQCSYHCQLCFLKKGLGIWYARQGRRRRTPRKTKTHPPPASDKSISTRTGDSQPTKKQKKTPETTVVSACGLGH
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: 6PGD_SHIFL
Sequence: MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLAPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELAQTFTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQSAGDKAEFIEKVRSALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDKEGVFHTEWLD
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: CASP2_WHEAT
Sequence: MDSGEQGETSKAPLNKGVSRGVSILDLILRVIAVISTLASAIAMGTTNETLPLFTPFIQFKARYSDLPALTFFVVANSIVSAYLILSLPLSIAHIIRSGAKYSRLVLIIFDAAMLALVTAASSAATAIVYLAHKGNVRANWLAICQQLDSFCERTSGSLVGSFGAMVLLILLILLSAMALARR
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 2, TaCASP2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: ATG15_ASPCL
Sequence: MKSSQRRIKRHAMRDMSISTLLLSVVLLPSVVSANDHVYFNPPSPGSPFLGPQIPLTGPPSLTNEHEFTLRHIYERGTNDQPDLHRRLDIKPHTRLWAVSDDGLEKELVTFDTPLVASSSPLTIQRLADRRPSVIEGYLTAARYNGEAVALSSSDWVMDTLAGPDVTKKETVLTFAKMTANDYIEEPGTEDWNYIHGRFNYSSSFGWQSDGLRGHIYADTKNNTIVISLKGTSPALFDGAGTTTNDKINDNLFFSCCCGQGGSYLWRQVCDCQQSAFTANLTCIAEAMNDENKYYRAAIDLYTNVTDMYPDANVWMTGHSLGGAMSSLLGLTFGLPVVTFEAVPEALPAARLGLPSPPGHDPRLPQTRKYTGTYHFGHTADPVYMGTCNGVGSICTWGGYAMESACHTGQMCVYDTVEDKGWRVALSTHRIKAVISDVLEVYDNVPPCAAEEECYDCELWKFFRSNGSETTTTSRTSTTTTPTTTRTLTCETPGWWGCLDESTTTTATTATSTTTTTSTCKTPGWFGCKDSTTTVDATAAPTVTTTIATPTTFPISSTTCKDPGWFGCRDPSSTTASVTAPPFSTSTSSDHVRADHSIGDGAAHPLTRMYLERLRQVEFAWGSDIEHYEI
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase atg15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: NSDHL_MOUSE
Sequence: MEQAVHGESKRGQVTGTHLTNDISKAKKCTVIGGSGFLGQHMVEQLLERGYTVNVFDIHQGFDNPRVQFFIGDLCNQQDLYPALKGVSTVFHCASPPPYSNNKELFYRVNFIGTKTVIETCREAGVQKLILTSSASVVFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLDANDPKKNFLTAAIRPHGIFGPRDPQLVPILIDAARKGKMKFMIGNGENLVDFTFVENVVHGHILAAEHLSQDAALGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWMAYYLAFLLSLLVMVVSPLIQIQPTFTPIRVALAGTFHYYSCEKAKKLFGYRPLVTMDEAVERTVQSFHHLRKDK
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (PubMed:10369263, PubMed:14567972).  Plays a role in the regulation of the endocytic trafficking of EGFR (PubMed:23125191).
What are the official names of this protein?
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Lipid droplet. Note=Trafficking through the Golgi is necessary for ER membrane localization.
Protein: TX18A_ODOMO
Sequence: MKLSALSLAFAIILMMTIMYTKADADASADAEADADAEAEAFWGALLAAAIPAITSAIQGK
What is the function of this protein?
Acidic peptide with potent hemolytic activities.  It also shows low antimicrobial activities against E. coli (MIC=50uM), as well as histamine-releasing activity (28. 3% at 10 uM).  Does not have activity against S. aureus, and S. cerevisiae.
What are the official names of this protein?
U-poneritoxin(01)-Om5b, U-PONTX(01)-Om5b, Pilosulin-like peptide 8, PLP8, Poneratoxin.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL19_ECO7I
Sequence: MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: MUTL_XANAC
Sequence: MAIRQLPEILINQIAAGEVVERPASVVKELVENALDAGATRVDIELEEGGVRLIRIRDNGGGITPDELPLAVSRHATSKIASLDDLETVATLGFRGEALPSIASVSRFTLTSRRHDAEHGSALEIDGGRLGEVVPRAHAPGTTVEVRELFFNVPARRKFLRAERTELGHIEEWLRSLALARPDVELRVSHNGKPSRRYKPGDLYSDARLGETLGDDFARQALRVDHSGAGLRLHGWVAQPHYSRASTDQQYLYVNGRSVRERSVAHAVKMAYGDVLFHGRQPAYVLFLELDPARVDVNVHPAKHEVRFREARLIHDFVYRTLQDALAHTRAGATPNSIGGDGTGYTAATSGGMGGIASGGVPGNGGASIGSGGAYSYASWTPSQTPLGLRVDEARAAYSALYAPPPSSAQQSAGMPNMAGTGLPATAQDSGVPPLGYAIAQLHGIYILAENAEGLIVVDMHAAHERIGYERLKHAHDSIGLHAQPLLVPMTLAVGEREADTAEREAETLATLGFEITRAGPQSLHVRSIPALLANAEPEALLRDVLSDLREHGQSRRIASARDELLSTMACHGAVRANRRLTVPEMNALLRDMEATERSGQCNHGRPTWARFTLSDIDRWFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: Y3036_ALKCK
Sequence: MNQSEVEIVIITGMSGAGKSVAVRSFEDLGYYCIDNLPPVLLPKFIELIEGGIDKVTKVALVMDLRGQSFFDELFKAIDELNETPASRLKIQILYLDAKDSKLVQRYKETRRTHPLAKGGLPLEGIQKERNLLEEIKGRAQQIIDTTELKPLQLREKIMQRFAGNDRQAFAVHFVSFGFKYGIPIDADLVFDVRFLPNPHYVEDLRPKTGLQTEVSSYVLKWKETKQFVEKLTDLFDFMLPHYKREGKSQVVIGIGCTGGQHRSVTLAEYFCAHYEAKYDAYTSHRDINKRKANSR
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein ABC3036.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: YT011_HUMAN
Sequence: MDCKSPKRANICPHLPGGGLFSTPPSQAAWRTLLTALCFPGPTCTGPMREGPRAVYNPPRAHRNSSDNCVMKHLLCAGDKNGTRRHALPSPLEGSFQPGRQIPPPQTPSTDPQTLPLSFRSLLRCHQLCAASLPPSLKLP
What are the official names of this protein?
Putative uncharacterized protein MGC163334.
Protein: HEM2_SHIFL
Sequence: MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: NU1M_DASNO
Sequence: MYLINVLSLIIPILLAVAFLTLLERKILGYMQLRKGPNIVGPYGLLQPIADAIKLFIKEPLRPATSSKLMFTLAPTLALTLALSLWIPIPMPYPLVNLNLGVLFILAMSSLAVYSILWSGWASNSKYALIGALRAVAQTISYEVTLAIILLSIMMTNGSFTLSTLTTTQEHMWLIFPLWPLAMMWFISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFALFFLAEYANIIMMNALTAILFFGAMHNPMFPELHTLNLITKTLILTMMFLWVRASYPRFRYDQLMHLLWKSFLPLTLALCMLHVSAPATFAGVPPHM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BBD2_ORYSJ
Sequence: MAMEGPILCRAVMQAKLPVTMISNSLTKSGQLGTAFLGCVCKYRNITRLISPIYQPAQKNFATVCGSFSSSSDGNGYMAGNFSESDEDYVNSTVLEAVEVRSGAEGYVIKMRDGKNLRCVHNNSQGRNIPESAPQPAIVLRIEDGSETLLPIIVLEMPSVLLMAAIRNVHIARPTIYQVVKEMIDKMGYEVKLVRINKRIQEAYCAELFLTKVGDHTESITFDLRPSDAINIAVRCKVPIQVHRSLAYSDGIRSVEPARMAIAAGMSDGLLFTELDRPDGQPCVEAQEFGLIRNMLIAAVEERYKDAATWRDKLMLLRSKRKNWA
What is the function of this protein?
Bifunctional nuclease with both RNase and DNase activities.  Involved in basal defense response.  Participates in abscisic acid-derived callose deposition following infection by a necrotrophic pathogen (By similarity).
What are the official names of this protein?
Bifunctional nuclease 2, OsBBD2.
What is the protein family that this protein belongs to?
Belongs to the bifunctional nuclease family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYR_PARPJ
Sequence: MLPAHKLTLETLLAETVKQVATASQGASEAAFVSPAITLERPKVAAHGDVACNVAMQLAKPLRANPRQLAQQIVDALLAQPQAKGLVEAAEVAGPGFINLRLAAAAKQAVIAAVFAEKEAFGRSQRDAGKHVLIEFVSANPTGPLHVGHGRQAALGDALSNVLASQGYDVHREFYYNDAGVQIQTLALSTQARARGLAPGDAGWPASAYNGEYIAEIARDYLNGVTVAASDGEPVTGARDVEDLEAIRRFAVAYLRREQDMDLQAFGVKFDQYYLESSLYKEGRVEKTVEALIAAGKTYEQEGALWLRTTDDGDDKDRVMRKTDGTYTYFVPDVAYHVAKWERGFTKVINVQGSDHHGTIARVRAGLQGLGVGIPKGYPDYILHKMVTVMRNGEEVKISKRAGSYVTVRDLIEWSGGATPGSEAAVDLIDEETIRRGRDAVRFFLISRKADTEFVFDIDLALKQNDENPVHYVQYAHARICSVIAECKARYSTDESTLADVDVSPLTSERAMALLNKLAEFPDMLQHAADELAPHAVAFYLRDLAGEFHSFYNDRTERVLVDDAAERNARVALLAATRQVLANGLATIGVSAPVKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_METMA
Sequence: MSVNRPRGTRDFLPADTARRRYVESVMRNVVLNWGYSEIITPTFEHLDLFTLKSGEGIIGELYNFTDKGGREMTLRPELTAPVMRFYVNELQPFPKPLKLFYFENCFRYERPQKGRFREFWQFGVELIGSGKSDSDAEVIALASALLKAVGIKGDMKLGNLAVIRTLLKGLEPEIVSNVMRLVDKKEYAGLEALLDEIGAEEQLKSDLFRLIHLQGRYILPEVKGIVGNIPELVSFEKTLKLLDAYGVDYSLDFGIARGLDYYTGMVFEVYAEGLGAQKQVCGGGSYQLIQLFGGGDVPSTGFGIGFDRIMEICPLVPPAQKSLVVVSKPDTHLEAVKVATELRNYLPVQIDLMERNFKAQLSYANTINADYVIIVGEKELEAGKLTLRDMVSGEQELLTLEEIIEKISGQ
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_CITK8
Sequence: MTIRNHTLGFPRVGLRRELKKAQESYWAGNATREDLLATGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNSDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPVTYLWLGKVKGESFDRLSLLNDILPVYKQVLTELAKRGVEWVQIDEPALVLELPQEWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTIAALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLVNGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCGELALLRDALNSGDTAKLEAWSAPIQARRHSTRVHNAAVEKRLAAITAQDSQRASPYAARAQAQRNRFNLPSWPTTTIGSFPQTTEIRGLRLDFKKGNLDANHYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPVVIGDVSRPEPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFEYPNEIGPGVYDIHSPNVPSVEWIEALLNKAAQRIPAERLWVNPDCGLKTRGWPETRAALANMVKAAQNLRQA
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: PSBZ_EUGGA
Sequence: NGWNDNKNFVLFGAAAWIGLVLLVGTLYYFVV
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: A1IA1_LOXHI
Sequence: WIMGHMVNAIYQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENYNDFLKGLRSATTPGNSKYQSKLILVVFDLKTGSLYDNQASEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFTDTLKQEGHPELLEKVGYDFSGNDAVGDVAKAYKKAGVSGHVWQSDGITNCLLRGLTRVKEAVANRDSGNGYINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVIADVMNEAAYKNKVRLATYEDSPWVTFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LhSicTox-alphaIA2ai, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ODP2_STAAC
Sequence: MAFEFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKSVVEIPSPVSGTVEEVMVEEGTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPAKEEAPAEQAPVATQTEEVDENRTVKAMPSVRKYAREKGVNIKAVSGSGKNGRITKEDVDAYLNGGAPTASNESAASATSEEVAETPAAPAAVTLEGDFPETTEKIPAMRRAIAKAMVNSKHTAPHVTLMDEIDVQALWDHRKKFKEIAAEQGTKLTFLPYVVKALVSALKKYPALNTSFNEEAGEIVHKHYWNIGIAADTDRGLLVPVVKHADRKSIFQISDEINELAVKARDGKLTADEMKGATCTISNIGSAGGQWFTPVINHPEVAILGIGRIAQKPIVKDGEIVAAPVLALSLSFDHRQIDGATGQNAMNHIKRLLNNPELLLMEG
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex, E2.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
Protein: RL33_FRASN
Sequence: MAATDVRPKITMACQVCKHRNYITRKNRRNDPDRLELRKFCPNCRTHTEHRETR
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: COAE_RHIEC
Sequence: MLKIGLTGSIGMGKSTVGKLFAEAGIPLNDSDAVVHNLYAGEAAPLVNAAFPGTMKDGAVDRHELGRQLALDPEGFKRLEAIVHPLVRKREMEFLAKQQADGAEMVLLDIPLLFETGAWERVDVIVVVSTDSQIQRQRVLAREDMTEEKFDMILSRQTPDAEKRRRADYLVDTSHSIAETRAQVLEIIAELKMRIAKGDFRNA
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OASL_HUMAN
Sequence: MALMQELYSTPASRLDSFVAQWLQPHREWKEEVLDAVRTVEEFLRQEHFQGKRGLDQDVRVLKVVKVGSFGNGTVLRSTREVELVAFLSCFHSFQEAAKHHKDVLRLIWKTMWQSQDLLDLGLEDLRMEQRVPDALVFTIQTRGTAEPITVTIVPAYRALGPSLPNSQPPPEVYVSLIKACGGPGNFCPSFSELQRNFVKHRPTKLKSLLRLVKHWYQQYVKARSPRANLPPLYALELLTIYAWEMGTEEDENFMLDEGFTTVMDLLLEYEVICIYWTKYYTLHNAIIEDCVRKQLKKERPIILDPADPTLNVAEGYRWDIVAQRASQCLKQDCCYDNRENPISSWNVKRARDIHLTVEQRGYPDFNLIVNPYEPIRKVKEKIRRTRGYSGLQRLSFQVPGSERQLLSSRCSLAKYGIFSHTHIYLLETIPSEIQVFVKNPDGGSYAYAINPNSFILGLKQQIEDQQGLPKKQQQLEFQGQVLQDWLGLGIYGIQDSDTLILSKKKGEALFPAS
What is the function of this protein?
Does not have 2'-5'-OAS activity, but can bind double-stranded RNA.  Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L.
What are the official names of this protein?
2'-5'-oligoadenylate synthase-like protein, 2'-5'-OAS-related protein, 2'-5'-OAS-RP, 59 kDa 2'-5'-oligoadenylate synthase-like protein, Thyroid receptor-interacting protein 14, TR-interacting protein 14, TRIP-14, p59 OASL, p59OASL.
What is the protein family that this protein belongs to?
Belongs to the 2-5A synthase family.
What are the subcellular locations of this protein?
[Isoform p56]: Nucleus, nucleolus. Cytoplasm. SUBCELLULAR LOCATION: [Isoform p30]: Cytoplasm.
Protein: TUSD_SALHS
Sequence: MRYAIMVTGPAYGTQQASSALQFAHALLNEGHELASVFFYREGVYNANLLTSPASDEYDLVRAWQKLNTQHGVALNICVAAALRRGIIDETEAGRLALPSANLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_MYXXD
Sequence: MSELILASTSSARRALMDGLRLPYRAEAPGVDEVVAPHLSVTEAVRELASRKARAVHQRHPEAWVLGADQLVEVAGEVLSKPVDRNAAREQLRKLVGHTHAIHTGVCLVGPGGKVLDAVETTRLTFYRVKEEELERYLDLNEWEGCCGSYRVEDAGQALLERLDGDRSNVQGLPMVTVVRLLREAGFRFF
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y803_CLOP1
Sequence: MRELYLKTLKKEVVPSEGCTEPIAIAYAASIAAEHLKGEIKEVNIYLSKNVIKNALGVGIPGTGGVGIEIAAALGISIQKSYKKLTILSNFTEDELKKAKEIVDKNIINIKQKNTNKALYIEVELLSETSKAKVIIEDTHTNVTLIECDDEIIMDNNSEVSEDLEEDYKLFKIADIYNFAKEVDFDHIKFILESAKMNEKVSEEGLKGDYGLQVGSKIIQKGNFNLFSNDASNKIIAASAAASDARMDGCAMPIMTTAGSGNQGIACSIPVAQTARLLDKSEEELARALVLSNLVTIRIKKHMGRLSPLCGAGIAGATGASCGITYLLGGDLENINYCINNMISDLSGMICDGAKETCALKIATGTNAAIQCANLAINGISATANDGIVAKDVEETIESIETLIQNGFKNVDDTILNIMLEKKKNNK
What are the official names of this protein?
UPF0597 protein CPF_0803.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: SYFA_TRIV2
Sequence: MTSNLEAQLLALRQEGEQAIAAADTLERLEELRVSYLGKKGQLGALLRSMGQMSAEERPKIGAIANTVKEALQASLDKQRESLESAQIQAQLDAETLDVTMPGIYKPQGRIHPLNGIIDRALDVFVGLGYTVAQGLEMETDYYNFEALNTPPDHPARDMQDTFYLPDGNLLRTHTSSVQIRYMEKEEPPIHIVAPGRVYRRDNVDATHSAVFHQIELLAIDEGLTFTDLKGTIKVFLQAMFGDLPIRFRASYFPFTEPSAEVDLQWNGRWLEVMGCGMVDPNVMKSVGYDPEIYTGFAAGFGVERFAMVLHQIDDIRRLYASDLRFLRQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_ECODH
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGYYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.