PharMolix/UniProtQA huggingface dataset:
Protein: UPP_RHILW
Sequence: MDGVTVIDHPLVQHKLTIMRRKETSTGSFRRLLREISTLLCYEVTRDLELTMETIETPLQTMESPILEGKKLVFASILRAGNGLLEGMLDLVPSARVSHIGVYRDHETLQPVEYYFKAPEDVAERLIIVVDPMLATGNSSIAAIDKLKERGAHNIRFLCLLAAPEGIQNFRAAHPDVPVFTASIDSHLNEKGYIVPGLGDAGDRMYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RS20_LISMH
Sequence: MPNIKSAIKRVKTAETRNSRNASQRSAMRTAIKKFDEAAANNADNAKDLYVEASKKLDSAVSKGLIHKNNAARNKSRLAAKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RT06_MOUSE
Sequence: MPRYELALILKAMRRPETAAALKRTIESLMDRGAIVRNLESLGERALPYRISSHSQQHSRGGYFLVDFYAPTSAVENILEHLARDIDVVRPNIVKHPLTQEVKECDGIVPVPLEEKLYSTKRRKK
What are the official names of this protein?
28S ribosomal protein S6, mitochondrial, MRP-S6, S6mt.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRAF7_MOUSE
Sequence: MPPINTPRRSDSAISVRSLHSESSMSLRSTFSLPEEEEEPEPLVFAEQPSVKLCCQLCCSVFKDPVITTCGHTFCRRCALKSEKCPVDNAKLTVVVNNIAVAEQIGELFIHCRHGCHAAGTGKPGVFEVDPRGCPFTIKLSARKDHESSCDYRPVRCPNNPSCPPLLKMNLEAHLKECEHIKCPHSKYGCTFIGNQDTYETHLETCRFEGLKEFLQQTDDRFHEMHVALAQKDQEIAFLRSMLGKLSEKIDQLEKSLELKFDVLDENQSKLSEDLMEFRRDASMLNDELSHINARLNMGILGSYDPQQIFKCKGTFVGHQGPVWCLCVYSMGDLLFSGSSDKTIKVWDTCTTYKCQKTLEGHDGIVLALCIQGCKLYSGSADCTIIVWDIQNLQKVNTIRAHDNPVCTLVSSHNMLFSGSLKAIKVWDIVGTELKLKKELTGLNHWVRALVAAQSYLYSGSYQTIKIWDIRTLDCIHVLQTSGGSVYSIAVTNHHIVCGTYENLIHVWDIESKEQVRTLTGHVGTVYALAVISTPDQTKVFSASYDRSLRVWSMDNMICTQTLLRHQGSVTALAVSRGRLFSGAVDSTVKVWTC
What is the function of this protein?
E3 ubiquitin ligase capable of auto-ubiquitination, following phosphorylation by MAP3K3.  Potentiates MEKK3-mediated activation of the NF-kappa-B, JUN/AP1 and DDIT3 transcriptional regulators.  Induces apoptosis when overexpressed.  Plays a role in the phosphorylation of MAPK1 and/or MAPK3, probably via its interaction with MAP3K3.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRAF7, RING-type E3 ubiquitin transferase TRAF7, TNF receptor-associated factor 7.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRAF7 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Colocalizes with MAP3K3 to vesicle-like structures throughout the cytoplasm.
Protein: LEPA_ANAMF
Sequence: MVGESTIRNFAIIAHIDHGKSTLADRLIEACNALSDRDMKDQVLDSMDIERERGITIKAQTVRLTYAAKDGVVYHLNLVDTPGHVDFSYEVSRSLAACEGSLLVIDSSQGVEAQTLANVYKAIENDHEIVTVLNKADLASSDPERVKSQVEEIIGLDASGALLISAKTGMGISDVLEAIVHRLPAPVGDANAPLKAILVDSWYDPYLGIVILLRVKDGVLKKGMKVAMLSTGAVYQVDNVGVFTPNKQMVDSLSVGEIGFITAGIKEIADCKVGDTLTEDSRRCDNPFPGFRATCPVVFCSLFPVDASSFEHLREALGKLQLNDSSFTFDMESSTALGYGFRCGFLGMLHLEVVQERLEREFDLDLTATAPSVVYRVTDKHRVTKEVHNPNDLPESHEILGVEEPWIAATIMVPDQYLGSILALCNSKRGEKVDLSYTGSMALLKYRLPLAEVVFDFYDSLKSVSKGYASLDWYVDGYVPTEISKLTILINSEPVDALSCIIHKSKVESRGREICERLKDLIPRQQYKVAIQAAVGAKIVARETISPYRKDVTAKVYGRDVTRKMKLLEKQKKGKKRLRSIGNVNVPQSAFIQALKMKD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CAV2_EULMM
Sequence: MGLETEKADVQLFLDDDSYSHHGDVDYADPEKFADSGHDRDPHRLNSHLKVGFEDVIAEPMTTHSCDKVWICSHALFEISKYVMYKFLTVFLAIPLAFAAGILFATLSCLHIWIIMPFVKTCLMVLPSVQTIWKSVTDVIIAPLCTSVGRSLSSISLQLSHD
What is the function of this protein?
May act as a scaffolding protein within caveolar membranes.  Interacts directly with G-protein alpha subunits and can functionally regulate their activity.  Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation.  The Ser-36 phosphorylated form has a role in modulating mitosis in endothelial cells.  Positive regulator of cellular mitogenesis of the MAPK signaling pathway.  Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
What are the official names of this protein?
Caveolin-2.
What is the protein family that this protein belongs to?
Belongs to the caveolin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Membrane, caveola; Peripheral membrane protein. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae. Tyr-19-phosphorylated form is enriched at sites of cell-cell contact and is translocated to the nucleus in complex with MAPK1 in response to insulin. Tyr-27-phosphorylated form is located both in the cytoplasm and plasma membrane. Ser-36- phosphorylated form resides in intracellular compartments (By similarity).
Protein: PUR9_ECO5E
Sequence: MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEMDDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SJL1_STIJA
Sequence: CSCYPDWMAIPGSGCYKYVDTPKTFEEAESTCRHFSPGPYGFGHLASVHSTEEYEALASMVPGATDSWNPQVFIGLRLIDGVSPAWTDGSYYDYQNWCGNDPNAHPDGYGAFSGGSYCNGQWVDVHTFTNDQFPFKCKLPCIE
What is the function of this protein?
May be calcium-dependent and galactose-specific.
What are the official names of this protein?
Lectin 1, Stichopus japonicus lectin 1, SjL-1.
Protein: RUVB_BORPE
Sequence: MAIQSDSLSSLPDSPRIVAPQPVSPNEESIERALRPKALEEYVGQQRAREQLEIFIAAARKRGEALDHVLLFGPPGLGKTTLAHIIAHEMGVQLRQTSGPVLERPGDLAALLTNLERNDVLFIDEIHRLSPVVEEILYPALEDFQIDILIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVSRLEFYNTDELARIVTRSASLLNADITADGAHEVARRSRGTPRIANRLLRRVRDYAQVKSHGVIDQDAAGRALAMLDVDPQGLDVMDRKLLEAIVHKFDGGPVGVDSLAAAIGEERDTIEDVIEPYLIQHGYLQRTPRGRTATLTTWRHLGLTPPAAASGGTGELFSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: ATPG_PROMS
Sequence: MANLKEIRDRIVSVKNTRKITEAMRLVAAAKVRRAQDQVLKSRPFADKLARVLENIQSRVQFEAVDSPLLSKREVKSISLVCITADRGLCGGYNTNIIKKVEIRYAELVKQGYQPNLILVGKKAIGYFQNRKDRYAIKSTFKELEQVPTVKDSEGVTNEILAEFLSENSDRVEIIYTKFITLVSCAPVVQTLLPLDPQGIAEENDEIFRLTTKDSKLLVEKSNIEKSDSEKLPSDIVFEQSPDQLLDSLLPLYLQNQVLRALQESAASELACRMTAMNNASDNAKELASTLNLTYNKARQAAITQEILEVVGGSAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: CASP2_CHICK
Sequence: MLGACGMQRYHQEALKKNRVMLARELVLKELMEHMIEKDIITIEMVEMIQAKSGSFSQNVEFLNLLPKRGPNAFSAFCEALQETKQQHLAEMILKTESSLRHGIATLEQRYGSNLPLPLSESCNSKRPRLIVEHSLDSGDGPPIPPVKHCTPEFYRDHQHLAYKLISEPRGLALILSNIHFSSEKDLEYRSGGDVDCASLELLFKHLGYQVTVFHDQSAEEMESALERFSKLPDHQDVDSCIVALLSHGVEGGVYGTDGKLLQLQEAFRLFDNANCPNLQNKPKMFFIQACRGDETDRGVDQRDGKERSDSPGCEESDANKEENLKLRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALTTVFAEDSRDTHVADMLVKVNRQIKQREGYAPGTEFHRCKEMSEYCSTLCRDLYLFPGYVPGK
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.
What are the official names of this protein?
Caspase-2, CASP-2, ICH-1L/1S, Protease ICH-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
Protein: FBD6_ARATH
Sequence: MDEDGEKHVLTKRSSFPESSDKNSGDEGDWVRRDLPESLLFQVLLNIPTKDLVKTSVVSPEWRHLWRCVPGLDLDEADFTQFDTLVSFIDSFLSINRESSLNKFKLRIYCNHDRDKETNNAHMARWISAIVEQNVQHVDLTWLPVEVPPILYLCESLVTLRLCGVVLANLEFMYLPLVKVLALEWVIFANELALEKLISGCLVLESLRFCKCSLDNVNVLRVRSQSLLSFNYYGPSSRDLHFKDLAVTIDAPKLEILKLSHQVTSSFIIKKLSSLVEANIKVEFNFCVGKKFNPNDLSKRKMILHFLVAISRVKNMTIAASTLEIIYDYSRCEPVPLFRNISLLRVEFYQDRWEISPFFLESCPNVKSLVVESDYYTKKRTSILSRPRRLLSSLEYVKIKSSWDKLEMKLVSYFIENSPVLKKVTLCLDGCSRKESVVLRELLTIPRRSSSCQVVVL
What are the official names of this protein?
FBD-associated F-box protein At1g66320.
Protein: MURI_STRP6
Sequence: MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKATLDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSIAKKIVYDSLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTANPEIFQEIASIWLKQKINVEHVTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: VG34_ICHVA
Sequence: MERVLRQLSTGSYGGRRCGGIEERIERWSRTTNSGTNTAGGWIPPPASFLMSNTVLRVHGSDPGFFIHVKHVNTVTNRQHMVRTVRVMPHKTIQSNVVKRATAKFVTDKKRISNVFGVKSTRIEFTTREHRSANYTANCKPLVQPTYKSYFNLIMQSHGECTIGTHRDVINNLNYTTYLYGVCNPMSTMVDSMKQKNFLTPFFFSSINLAGPIETTNQLFISMTINTQKLTHETIYDLGKTLYPIYSLLEVDTKFNWFCNMIALFLECFINTPNKIGMIWMNERYYLENPTENATRSTETWNEYRKYMLEKCAPLLNGFSMAFAQRTGQFVYKNCEMVHIAPFFVAAALEEAVLSYGSFLLNTRKIKSFKELVMMLSVTPTDPRLTVTQTDDRTDVYRTGDRVLTWSHGADFKVGASERLVLGKKINQYIKCKTGDHGDQD
What are the official names of this protein?
Uncharacterized protein ORF34.
Protein: SUCB1_MESAU
Sequence: DVVIKAQVLAGGRIVFSPEEAKLITKQTGAKGRICNQVLVCERREYYFAITMERSFQGPVLIGSAQGGVNIEDVAAENPEAIVKKMGFPSNIVDSAAENMIKLYNLFLKINFDSNSAYRQKIFDLQDWSQEDERLHGGTPANFLDVGGGATVQQVTEAFKVQAILVNIFGGIMRLQGTRVDDAKILACDDLDEAAKMVVKLSEIVTLAKEAHVDVKFQLPI
What is the function of this protein?
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, ATP-specific succinyl-CoA synthetase subunit beta, A-SCS, Succinyl-CoA synthetase beta-A chain, SCS-betaA.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y776_NATPD
Sequence: MAADHYVYVLSCADETLYTGYTTNVERRVAEHDAGEGAKYTRGRTPVELVHTERFDSKSAAMQREHEIKSLSRAKKERLVADETG
What are the official names of this protein?
UPF0213 protein NP_0776A.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: CH60_XANAC
Sequence: MAAKDIRFGEDARTRMVRGVNVLANAVKATLGPKGRNVVLEKSFGAPTITKDGVSVAKEIELADKFENMGAQMVKEVASKTNDNAGDGTTTATVLAQALIREGAKAVAAGMNPMDLKRGIDQAVKAAVVELKNISKPTTDDKAIAQVGTISANSDESIGNIIAEAMKKVGKEGVITVEEGSGLENELDVVEGMQFDRGYLSPYFINNQQSQSADLDDPFILLHDKKISNVRDLLPVLEGVAKAGKPLLIVAEEVEGEALATLVVNTIRGIVKVVAVKAPGFGDRRKAMLEDMAVLTGGTVISEEVGLALEKATIKDLGRAKKVQVSKENTTIIDGAGDSAAIESRVGQIKTQIEDTSSDYDREKLQERVAKLAGGVAVIKVGASTEIEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALVAVGDLKGANEDQTHGIQIALRAMEAPLREIVANAGEEPSVILNKVKEGTGNYGYNAANGEFGDMVEFGILDPTKVTRSALQNAASIAGLMITTEAMVADAPKKDEPALPAGGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP54_SYNE7
Sequence: MFDALAERLEQAWTKLRGQDKISESNVQEALKEVRRALLEADVNLGVVKEFIAQVQEKAVGTQVISGIRPDQQFIKVVYDELVQVMGETHVPLAQAAKAPTVILMAGLQGAGKTTATAKLALHLRKEGRSTLLVATDVYRPAAIDQLITLGKQIDVPVFELGSDANPVEIARQGVEKARQEGIDTVIVDTAGRLQIDTEMMEELAQVKEAIAPHEVLLVVDSMIGQEAASLTRSFHERIGITGAILTKLDGDSRGGAALSIRRVSGQPIKFVGLGEKVEALQPFHPERMASRILGMGDVLTLVEKAQEEIDLADVEKMQEKILAAKFDFTDFLKQMRLLKNMGSLAGFIKLIPGLGGKINDEQLRQGERQLKRVEAMINSMTPQERRDPDLLSNSPSRRHRIAKGCGQTEAEIRQIIQQFQQMRTMMQQMSQGGFPGMGGMGMPGFGGGMPGFGGGAPAPQPGFRGYGPPKKQKKGSKKKKGFGL
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: FOLD_BRUSI
Sequence: MAQLIDGKKLAEDVVSTVKTETEKLVAATGVVPGIAVVIVGEDPASQVYVASKSRKAKECGFHSVQHDLPETASEQELLNLIEGLNNDPAIHGILVQLPLPGHIDSGRVIQTIAPEKDVDGFHFINVGKLGTGEVETAFVPCTPAGAMIMIERVHGRDLSGLNAVVIGRSNIVGKPMFNLLLAANATVTVAHSRTKDLPAIARNADILVAAVGRPQMVKGDWVKPGATVIDVGINRIPAPERGEGKTRLVGDVDFAEAEKVAGAITPVPGGVGPMTIAMLMANTLTAACRSAGMKKPVF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: GATC_RICCK
Sequence: MITKEEAQKIAKLARLKFEEDTVEKFSTQLSSIMNMIDILNEIDCKDIEPLTSVSNMNARMREDEVTSSDLSDKLLDHVSGQSAQLAKEVKYFITPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: Y260_STRP3
Sequence: MNDHVIYTQSDVGLNQFFAKIYSLVGMGVGLSAFVSYLMLYPFRENLISILVNQPMIYYGAAIIELILVFVASGAARKNTPAALPIFLIYAALNGFTLSFIIVAYAQTTVFQAFLSSAAVFFAMSIIGVKTKRDMSGLRKAMFAALIGVVVASLINLFIGSGMMSYVISVISVLIFSGLIASDNQMIKRVYQATNGQVGDGWAVAMALSLYLDFINLFISLLRIFGRND
What are the official names of this protein?
Uncharacterized membrane protein SpyM3_0260.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASTE_SHEPA
Sequence: MFQQLKQSKDFLALTLAHPQYLTESFEFDLANQVHVEVWDTGVIMFEPLGVKHTKDLVLSCAVHGNETAPIELCNDLMTQLLDEQLVLKQRVLFLIGNPPAIHNGTRFIDENLNRLFNGAHSRGEGLCNPERVRAQKLEQYVDKFFSAHSGERHRMHYDLHTAIRASKHEKFAIYPYRGNRKYSKEQIMFLESCGVNTILFHHEPTTTFSYFSSENYHADAFTIELGKVFPMGQNDMTRFIAMKEMLTLLMCGEELKLPSFDMKRLNLYQVCRSVNKRYDDFEFTFTNDVENFTAFPRGYTLAKEGGFEVKVEHEFESIVFPNAKVPVGQRTVLCLKSADESRLD
What is the function of this protein?
Transforms N(2)-succinylglutamate into succinate and glutamate.
What are the official names of this protein?
Succinylglutamate desuccinylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
Protein: CLCD_PSEPU
Sequence: MLTEGISIQSYDGHTFGALVGSPAKAPAPVIVIAQEIFGVNAFMRETVSWLVDQGYAAVCPDLYARQAPGTALDPQDERQREQAYKLWQAFDMEAGVGDLEAAIRYARHQPYSNGKVGLVGYCLGGALAFLVAAKGYVDRAVGYYGVGLEKQLKKVPEVKHPALFHMGGQDHFVPAPSRQLITEGFGANPLLQVHWYEEAGHSFARTSSSGYVASAAALANERRLDFLAPLQSKKP
What is the function of this protein?
Ring cleavage of cyclic ester dienelactone to produce maleylacetate.
What are the official names of this protein?
Carboxymethylenebutenolidase, Dienelactone hydrolase, DLH.
What is the protein family that this protein belongs to?
Belongs to the dienelactone hydrolase family.
Protein: VATE_DEIRA
Sequence: MALDKLLENEAQSEIERIRAEARGRAEKIVADARERAQTLLDSRQRLLENQRQAGLVRARSAADLELNAARLTASESGVTQVYQMVEDYLGNVTSAPEYGNILSRLIQEGLQAVPDAEAIEVNPAEMNVARHLVSGVEVRENPSIKGGVRVVARGGKSGVTNTLSGRLERVKADMAPQISRLLAE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: TA2R_MOUSE
Sequence: MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
What is the function of this protein?
Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation.  The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.  In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction.  Activates phospholipase C and adenylyl cyclase.
What are the official names of this protein?
Thromboxane A2 receptor, TXA2-R, Prostanoid TP receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATTA_TRINI
Sequence: MFTYKLILGLVLVVSASARYLVFEDLEGESYLVPNQAEDEQVLEGEPFYENAVQLASPRVRRQAQGSVTLNSDGSMGLGAKVPIVGNEKNVLSALGSVDLNDQLKPASRGMGLALDNVNGHGLSVMKETVPGFGDRLTGAGRVNVFHNDNHDISAKAFVTKNMPDFPNVPNFNTVGGGVDYMYKNKVGASLGMANTPFLDRKDYSAMGNLNVFRSPTTSVDFNAGFKKFDTPVFKSNWEPNFGLTFSRSFGNKW
What is the function of this protein?
Hemolymph antibacterial protein.
What are the official names of this protein?
Attacin-A.
What is the protein family that this protein belongs to?
Belongs to the attacin/sarcotoxin-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1125_STRA5
Sequence: MLFKEKIPGLILCFIIAIPSWLLGLYLPLIGAPVFAILIGIIVGSFYQNRQLFNKGIAFTSKYILQTAVVLLGFGLNLMQVMKVGISSLPIIIMTISISLIIAYVLQKLFKLDKTIATLIGVGSSICGGSAIAATAPVINAKDDEVAQAISVIFLFNILAALIFPTLGNFIGLSDHGFALFAGTAVNDTSSVTATATAWDAINHSNTLGGATIVKLTRTLAIIPITIVLSIYHMKQTQKEQSVSVTKIFPKFVLYFILASLLTTIVASLGFSLRIFEPLKVLSKFFIVMAMGAIGINTNVSKLIKTGGKSILLGAACWLGIIIVSLTMQAILGTW
What are the official names of this protein?
UPF0324 membrane protein SAG1125.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CAS1_METKA
Sequence: MGAPNDTVIFLRRGKIERREDAFRIGKSKYSAVRTTGIIIAGGAQITTQAVRLALRNEVPIVYLGGNRILGVTVPFSERYATLRLKQYEIASQPSARLAFARPLIASSILARAAVLEFLANETGITGLEDAADEVRSEAERALNAGSTDALRGYEGRAACRYFRALAEVLPDWAFSGRRTRRPPRDPFNAAISFGYAGVLLPVLLSRTVAAGLEPFLGFLHGPRGRRPGLILDLMEEWRALAVDVPVLRRFLDGSLSREMFRWKGDAVLLRDLDAVSAPVLTVLSRVRGGLLEAVDRRIREVRDGVSRQSPPEPLEFDPEDVGVVWDALEV
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: THIG_BARHE
Sequence: MLNLYGHKFSSRLMLGTAQYPSPAILRDAIHKSNTEIVTVSLRRETAGGKQGGQFWQFLKELDITVLPNTAGCYTVKEAVTTAKLARDLFKTSWIKLEIIGNPDTLQPNVFSLVEAAKILNSEGFKIFAYTTDDLIVAEKLLDVGCQVIMPWCAPIGSAKGPHNTDGLRSIRAYLPDVTLVIDAGIGRPSHATVAMELGYDAVLLNTAVAKAADPVLMAEAFSKAIQAGRMGYKAGILEARNVAVPSTPIIGKAVFS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.