PharMolix/UniProtQA huggingface dataset:
Protein: ECFA_MALP2
Sequence: MEKDIKKNEIENKNREKAFEIQNVSFSYDLVNNVLNDVSFDIYENEYVCIIGHNGSGKSTISKVLVGLLKPHQGNLKIFGETISYLNFFHLRTNVGIIFQNPDSQFIGLSAKDDIAFGLENRKINPSVMDDIIESASEVVDIKELLDKDSSSLSGGQKQRVAIASVLATNPRIIIFDESTSMLDPRGKMELKKIMLDLKNKANKTVISITHDMDEVLNADRVIVFKKGQIIRTGKPSEIFTDEEFLASSALDFPFILKLSKELKSKNVNVNFTINKEQLLDQICKKK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA, ECF transporter A component EcfA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: IMDH_STAA8
Sequence: MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase, IMP dehydrogenase, IMPD, IMPDH.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
Protein: Y1998_PARUW
Sequence: MLFPISKQALSCPHFDSCAGCSHQLFVEPPIWREVIENFKETLNPILHQGTLTGWRCRAKLAVRGTKQNPIIGLFKKGSHEALNIPFCLVHHPRINQAVTMIQNWMERHQLNPYQEHSQAGDLRYLQFVVERASGKVQIVFVLNFKDFSSPESQIWRKLLLELAQETTNAFWHSIWVNFNPHATNTIFTDKWEKVWGEPYLWESFDGVKICFQPSNFAQANLDLFEKLLKKVKSWVREKAKVVEFFAGVGTIGLSVAAKCSWIKCEEINPHSKECFYYAKQQLSSEISQKIMFYTGSADENLNLLQGADTVIVDPPRKGLSRKFIEGLTQSSVDQLIYVSCGWDSFKKNKETLISQGWNLKKLEGYSLFPGSEHIELLTLFER
What are the official names of this protein?
Uncharacterized RNA methyltransferase pc1998.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: COX16_PHANO
Sequence: MPGPFSSRSFAATLPNSIAARYRKQLQKHPFLLFGLPFMATIVAGSFMLTPATALRYERYDRKNQQITQEEAMGLRQERRKVNMKDEYYRLQAKDLEDWEQRRVKRLPGEPDGTLV
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  May participate in merging the COX1 and COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL35_HELPS
Sequence: MPKMKTNRGASKRFKVKKNLIKRGSAFKSHILTKKSPKRKANLNAPKHVHHTNAHSVMSLLCRA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GLNA3_HALMT
Sequence: MTEDNVLTDGGLSAEAQAVIDEIEEKNVDFLRLQFTDILGTVKNVSIPASQAEKAFTEGIYFDGSSIDGFVRIQESDMRLEPDPSTFAILPWRKKENSAAARLICDVFNTSTGEPFSGDPRGVLKRAIERAEDMGYDINAAPEPEFFLFEEDEDGSATTITNDAGGYFDLAPKDLASDVRRDIIYGLESMGFDIEASHHEVAEGQHEINFTYDDALSTADNVATFRSVVRAIAAEHDLHATFMPKPIAKVNGSGMHTHISLFKDGENAFHDGADEFDLSETAKQFTAGILEHAPAVTAVANPTVNSYKRLVPGYEAPVYIAWSDRNRSALIRKPAARTPAASRIEARFPDPSCNPYLALAALIHAGLDGIERELDCADPVRENIYEFDEEKREEYGIETLPKDLGAAVDALEEDEVIQNALGEHVTEKFVEAKRSEFKDYLVAVSEWEIDRYLETF
What is the function of this protein?
Probably involved in nitrogen metabolism via ammonium assimilation.  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase 3, GS3, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBL_HUMAN
Sequence: MDAPRASAAKPPTGRKMKARAPPPPGKAATLHVHSDQKPPHDGALGSQQNLVRMKEALRASTMDVTVVLPSGLEKRSVLNGSHAMMDLLVELCLQNHLNPSHHALEIRSSETQQPLSFKPNTLIGTLNVHTVFLKEKVPEEKVKPGPPKVPEKSVRLVVNYLRTQKAVVRVSPEVPLQNILPVICAKCEVSPEHVVLLRDNIAGEELELSKSLNELGIKELYAWDNRRETFRKSSLGNDETDKEKKKFLGFFKVNKRSNSKGCLTTPNSPSMHSRSLTLGPSLSLGSISGVSVKSEMKKRRAPPPPGSGPPVQDKASEKVSLGSQIDLQKKKRRAPAPPPPQPPPPSPLIPNRTEDKEENRKSTMVSLPLGSGSHCSPDGAPQVLSEAEETVSVGSCFASEDTTEDSGVMSSPSDIVSLDSQQDSMKYKDKWATDQEDCSDQDLAGTPDLGPQKSPLWEKNGSENSHLRTEKAVTASNDEEDLLIAGEFRKTLAELDEDLEEMEDSYETDTSSLTSSIHGASNHCPQDAMIPHGDTDAIPVTFIGEVSDDPVDSGLFSNRNNNAGSFDSEGVASRRDSLAPLQAEHSQPHEKAREEVPALHPASHDVGKGIRVALSNISKDGNLMETAPRVTSFASNLHTDNLNAKVKDKVYGCADGERTQATERVNSQPVNEKDSNDKNAALAPTSWHQRGQNPGKSYRLKHGLTTYKIIPPKSEMRCYDRDVSLSTGAIKIDELGNLVSPHATGIRIISLSSSVPEAESQPIGKVREFWRCNSVEKHLGRPSESSARGPPSTPVPTQTQNPESRLQADPKPISPQQKSAHHEGRNPLGEGRNQPPTMGMGHVRVPAAHTTEVTFLKPQRRTSSQYVASAIAKRIGAPKVHADVVRPHGYAEKGYAGKAPVLAAPPVTVKDDRTSSPHSETQGWKDGAQWPCVTPPNNHGEDLAVGAPPRGEVIGPHRKLSTQDRPAAIHRSSCFSLVQSSQRDRVSVGQSCGFSGKQSTSSQEASSASEPRRAPDGTDPPPPHTSDTQACSRELVNGSVRAPGHGEPSHPPGGSGTESHILLEREEKPSVFSTDGNETDSIWPPSIFGPKKKFKPVVQRPVPKDTSLHSALMEAIHSAGGKDRLRKTAEHTGEGRPAKLSYTEAEGERSALLAAIRGHSGTCSLRKVASSASEELQSFRDAALSAQGSESPLLEDLGLLSPPAIPPPPPPPSQALSAPRTASRFSTGTLSNTADARQALMDAIRSGTGAARLRKVPLLV
What is the function of this protein?
Plays an important role in the reorganization of the actin cytoskeleton.  Regulates neuron morphogenesis and increases branching of axons and dendrites.  Regulates dendrite branching in Purkinje cells (By similarity).  Binds to and sequesters actin monomers (G actin).  Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end.  Can also mediate actin depolymerization at barbed ends and severing of actin filaments.  Promotes formation of cell ruffles.
What are the official names of this protein?
Protein cordon-bleu.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, ruffle. Cytoplasm. Note=Recruited to the cell membrane via interaction with PACSIN1. Colocalizes with the actin cytoskeleton. Detected throughout the neuron cell body, as well as in axons and dendrites (By similarity).
Protein: TRHO_PSEAE
Sequence: MTSIVVAALYKFVTLDDYVALREPLLQTLLDNGVKGTLLLAEEGINGTVSGSREGIDALFAWLRSDPRLADIEHKESYCDEQPFYRTKVKLKKEIVTLGVPGVDPNKQVGQYVEAKDWNALISDPEVLLIDTRNDYEVAIGTFEGAVDPKTRSFREFPEYIKAHYDPARHKKVAMFCTGGIRCEKASSYMLGAGFEEVFHLKGGILKYLEEVPQEQSLWRGDCFVFDNRVTVRHDLSEGEYDQCHACRNPVSLEDRQSEHYVPGISCPHCWDSLSEKTRAGARERQKQIELARQRNQPHPLGRDPRQSTLEN
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ADDB_CLOD6
Sequence: MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTFEAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAIEDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKDISKIYNSFEGKLHENYVDAQDMLTSLTSKIELSSYLDGACVYIDEFTGFTPNQYNVIKSILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNTGVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVRDKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMKNRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIESLIVNFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYELGLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKGIEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPNIENKSYLVEENKNTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYRYYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYFIQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIVDEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGDNGKYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQLQLLVYLDAILESAKDEDMNINPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKGLVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRHAIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEIIKMMKGDVN
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: TLCA_RICPR
Sequence: MSTSKSENYLSELRKIIWPIEQYENKKFLPLAFMMFCILLNYSTLRSIKDGFVVTDIGTESISFLKTYIVLPSAVIAMIIYVKLCDILKQENVFYVITSFFLGYFALFAFVLYPYPDLVHPDHKTIESLSLAYPNFKWFIKIVGKWSFASFYTIAELWGTMMLSLLFWQFANQITKIAEAKRFYSMFGLLANLALPVTSVVIGYFLHEKTQIVAEHLKFVPLFVIMITSSFLIILTYRWMNKNVLTDPRLYDPALVKEKKTKAKLSFIESLKMIFTSKYVGYIALLIIAYGVSVNLVEGVWKSKVKELYPTKEAYTIYMGQFQFYQGWVAIAFMLIGSNILRKVSWLTAAMITPLMMFITGAAFFSFIFFDSVIAMNLTGILASSPLTLAVMIGMIQNVLSKGVKYSLFDATKNMAYIPLDKDLRVKGQAAVEVIGGRLGKSGGAIIQSTFFILFPVFGFIEATPYFASIFFIIVILWIFAVKGLNKEYQVLVNKNEK
What is the function of this protein?
Provides the rickettsial cell with host ATP in exchange for rickettsial ADP.  This is an obligate exchange system.  This energy acquiring activity is an important component of rickettsial parasitism.
What are the official names of this protein?
ADP,ATP carrier protein 1, ADP/ATP translocase 1.
What is the protein family that this protein belongs to?
Belongs to the ADP/ATP translocase tlc family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRL4B_LUPAN
Sequence: MALVTTTPTVNDEPLFAEVDMASYFTSTTVRATVVQASTIFYDTPATLDKAERLLVQAASYGAQIVVFPEAFIGGYPRGSNFGVSIGNRTAKGKEEFRKYHSAAIDVPGPEVDRLSAMAGKYKVYLVMGVIERDGYTLYCTVLFFDSQGRYLGKHRKVMPTALERIIWGFGDGSTIPVFQTPIGKIGAAICWENKMPLLRTAMYAKGVEIYCAPTADSRDLWQASTTHIALEGGCFVLSANQFCRRKDYPPPPEYVFSGTEEDLTPDSVVSAGGSVIISPSGAVLAGPNYEGEALISADLDLGEIARAKFDFDVVGHYSRSEVLSLIVKDHPTNPVTFTSTSTKIEDQTK
What is the function of this protein?
Involved in the cyanide detoxification pathway.  Has nitrilase and nitrile-hydratase activity in the ratio 3. 3:1, producing both asparagine and aspartic acid from beta-cyano-L-alanine (Ala(CN)).  Can also use 3-phenylpropionitrile as substrate, but not indole-3-acetonitrile.
What are the official names of this protein?
Bifunctional nitrilase/nitrile hydratase NIT4B, LaNIT4B, 3-cyanoalanine hydratase, Cyanoalanine nitrilase B.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: F16PA_VIBPA
Sequence: MSGMRTLGEFIVEKQADFPHASGDLSSLLASIRLAAKIVNREINAAGLGDITGAVGTENVQGEAQQKLDVYANDKFKAALEARDQVCGVASEEEDEAVAFNKELNQNAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVSPIGTPATEEDFLQPGHKQVAAGYVIYGSSTMLVYTTGNGVNGFTYDPSIGSFCLSHENMMIPEDGKIYSINEGNYIRFPQGVKKYIKYCQENVPEDGRPYTSRYIGSLVADFHRNLLKGGIYLYPSTQSHPQGKLRLLYECNPMAFLIEQAGGIASDGVNRIMDIKPTELHQRVPFFVGSKNMVRKVEEFLELHRDEE
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEL1_SCHPO
Sequence: MSHASKNYNAQLTAAAASTALHGTKKIYNSNENDRAVNSFLGNRTSYGEAVNGSPQYDYMRSRMSTLGSANQPMAPPSLRNRSSVYLPTPAGPPQIPVNTGKRYTLTSSSANYMTKSERQMRPPKSYDFPPSQQVRPSTSRSPSYASYNSEEVNFQSYQDPRLLPRTSQMYMPDNNYSPAVKSPAAQRRSSSYMVPANSRGSPANYNTPYYPTAIPPPIEEYSPSVSLPTSPVAEESYNNVQRSSTVRNNTTQKSVLKKPSRKMSPAYTSSYRQNSPSSQVPPVSKKHVIIYENKEGSSSSESVYEDVFEDFDPSGSNQASLRSTSTIHYTPSSKRISVIPPNTSNIGSRVVSRSGQNNNQPAQPGQYNQQSQPVQSYQSGQSTQHFQPVQPIQPVQSTQYYQPSSPVQPVQNGVPAPPMQPVQSTQYYQPSSPVQPVQNVKPAQPAQPSLEDAAKRRVEEMLRQMDITPTASSTTANNAYASAEPHPSAFPDDMNSVFSDSSFERERDSGRGRSTNLFSKFKSGRSRSKASGEAPYSYPAPPVPSVNNAGARLTLRDSGAAPEATYSLRQPSNHAYSEGRSYTFTGGQPPSVPTMPYGSRFANDSDSMMGSTADFSSKKKGGKFKAFKKFFKMRF
What is the function of this protein?
Important for the biogenesis of filamentous eisosomes, large cytoplasmic protein assemblies that localize to specialized domains on the plasma membrane to cluster specific proteins at sites of membrane invaginations.
What are the official names of this protein?
Eisosome protein sle1, SEG1-like eisosome protein 1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell tip. Note=Localizes to eisosomes.
Protein: Y1057_GEOSW
Sequence: MGIKFINIGYGNMVSAARIITIVSPDSAPIKRIIQDARESGKLVDATHGRRTRAVIIMDSDHVILSSVQPETVANRLYGSDDLSEEG
What are the official names of this protein?
Putative regulatory protein GWCH70_1057.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: FIBB_PIG
Sequence: AIDYDEDEDGRPKVHVDAR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen beta chain.
What are the subcellular locations of this protein?
Secreted.
Protein: YSCR_SALTY
Sequence: MSLPDSPLQLIGILFLLSILPLIIVMGTSFLKLAVVFSILRNALGIQQVPPNIALYGLALVLSLFIMGPTLLAVKERWHPVQVAGAPFWTSEWDSKALAPYRQFLQKNSEEKEANYFRNLIKRTWPEDIKRKIKPDSLLILIPAFTVSQLTQAFRIGLLIYLPFLAIDLLISNILLAMGMMMVSPMTISLPFKLLIFLLAGGWDLTLAQLVQSFS
What are the official names of this protein?
Virulence protein YscR.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPH_XANOM
Sequence: MYVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEELDEVPDDATVIFSAHGVPQAVRQEAERRGLKVFDATCPLVTKVHFEVARHCRAGRDVVLIGHAGHPEVEGTMGQWSRERGPGTIYLVEDIEQVATLDVRQPENLAYTTQTTLSVDDTMGIIEALRARYPAMQGPRHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRDGVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGASGVSELEGEPESMVFALPKELRLRLVG
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: MARH2_DANRE
Sequence: MTTGECCHLPGSLCDCTGNAALSKTVEEADNRRAQYVTQVTAKDGRLLSTVIKALGTQSDRPICRICHEGQDVCNSEGLLSPCDCTGTLGTVHKSCLEKWLSSSNTSYCELCHTEFTIERRPRPLTEWLRDPGPRNEKRTLFCDMVCFLFITPLAAISGWLCLRGAQDHLHFNSRLEAVGLIALTIALFTIYVLWTLVSFRYHCQLYSEWRRTNQKVRLLIPDTKGAHSTQHSLLSTKLLKKTADETIV
What is the function of this protein?
E3 ubiquitin-protein ligase which may be involved in endosomal trafficking.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF2, Membrane-associated RING finger protein 2, Membrane-associated RING-CH protein II, MARCH-II, RING finger protein 172, RING-type E3 ubiquitin transferase MARCHF2.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi- pass membrane protein. Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasm. Cell membrane; Multi-pass membrane protein.
Protein: HISZ_GEOSL
Sequence: MTPITPIEAPLPKGVTDFLPEKADKIGYIEGKIRKVFELWGFRRIITPLLEFEDVIAAGLGDDLKAKTFRFDDRQSGKLIAVPSDITPQIARIVATRLRGYPLPHRICYSGRVLRHAELQSGRSREIFQSGVELIGLDSPEADAEMVTMAVEALKGLGFRDFKIDLGHVGFIRGIMTASGLEVAVRNRLQEAIGKKDVSAVRSILAESPLSDAAKDELAALPRLFGGREVLDEAGRVATNDTSRRALDNISQVLDLLDIHGVSDHLTIDLGEVRGLDYHTGLTFEGFVTGMGEAVCSGGRYDTLTARYGFPAPATGFTFNVLALLSALEKRPDVEASKTRDILIFNQQDDRREALEIAQQLRRRGYTTARDIIRRNFDDSLDYARRMNILHMMVVGGDQCGPDEVYLVRVADGQGQRIKKAEVFSERFSLDAGPDKES
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_CHLVU
Sequence: MTNIWFDVAEVSVGQHWYWQLGGYSLHGQVLITSWIVVAVIGVICLLGTQNLQPVSGGSAATAPKGLQNLTEYITEFIRDLAKTQIGEEDYLKWVPFLGTIFLFIFVSNWSGALIPWRILELPNGELAAPTNDINTTVALALLTSIAYFYAGISKKGLGYFKRYISPAAFLLPINILEDLTKPLSLSFRLFGNILADELVVGVLVSLVPLVVPIPIMLLGLFTSAIQALVFATLAGAYIGESVEDHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FBL54_ARATH
Sequence: MDICCKDIISDHSKKDIISDLPEALICHILSFLPIEDSALTSVLSKKWQHLFAFRPNLEFDDAVVYLNPDGERNETIFENFVDRVLSLQGDYPINKFSLTCRDFTDPTCVSRWISNVMERGVSDLDLRCIVYWDNGTMPPDIFVSKALVHLRIETGNGAFIDVEDVFLPNLKTLYLNKVLLRHSDNGFVKLITSCHVLEDLFIMNICWDGYLKRSLSSKTLKRLTFFCEDVHAVNPESVSFDTPNLVYFVYHDCVADKYKNMNFDSLVYASICLQMTSHQRTHASYEHLVGNATDFLLGISNVQILELFANTIEVLTFCCEQIPVFKNLVCLIIKTDQKAGWESLPVLLKNCPDLESLIFDGLHHNDTIKCEDVDGCLCKSSRGIPSCLSSSPVQFLTIWKFGEICDDYDDMEKQIELVMYFLETMPNLEEMKLFYDTQIYEDVISKLQMDLRRTLSLRSLFNARCYQPSCSGIIQRDDVHEEKPHYGSFLHQRSFSSSMILSQQHMMRSPSHFPLCSPFGVSTYRPMSTSHISGSDESGDVNHVAETLTDLVQQDTVIEVADAAIDSSIQLDFVQQIVHNVHSLTGLNWWASIVFTTFLIRGVTIPLMIECERWFSKRMVIKQCSFVNT
What are the official names of this protein?
Putative F-box/LRR-repeat protein At3g49150.
Protein: RU1C_MACMU
Sequence: MPKFYCDYCDTYLTHDSPSVRKTHCSGRKHKENVKDYYQKWMEEQAQSLIDKTTAAFQQGKIPPTPFSAPPPAGAMIPPPPSLPGPPRPGMMPAPHMGGPPMMPMMGPPPPGMMPVGPAPGMRPPMGGHMPMMPGPPMMRPPARPMMVPTRPGMTRPDR
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YBFE_ECOLI
Sequence: MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKRDKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV
What are the official names of this protein?
Uncharacterized protein YbfE.
Protein: TBCA_RABIT
Sequence: MADPRVRQIKIKTGVVKRLVKEKVMYEKEAKQQEEKIEKMRAEDGENYAIKKQAEILQESRMMIPDCQRRLEAACTDLQQILESEKDLEEAEEYKEARLVLDSVKLEA
What is the function of this protein?
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
What are the official names of this protein?
Tubulin-specific chaperone A, TCP1-chaperonin cofactor A, Tubulin-folding cofactor A, CFA.
What is the protein family that this protein belongs to?
Belongs to the TBCA family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: SRA13_CAEEL
Sequence: MAIISSVNRTCASESLLELYRSYKYILSTSFNIIIPIISLFFLVYAIKQLCAQSIIQYSTRVLLITTILFAVCHQIAYFCFKADLLYTMLFKLDQPCNLQHSSYDCRFITIATTTSNCGMALVQLAMSIDRVFALKFNRVYYKLKSIPGITLALITLSISFSMFFILTIDDPLSGYVNHCGFYPTYSQDKFHIFLDVTLYLAVFNFVFDIGLMYYSYQEILWKRSYSFVNRFQSRISLKCTQAIFIISICQCISNVLYSGLLSLLMKLGRYMSSADYNLSLSLAYTTPYSCLILPILICKVLEYIKKQRTVGILSLRNQKQSMEGHMAMINSAWK
What is the function of this protein?
Chemosensory receptor that negatively regulates RAS/MAPK signaling during vulva induction and the negative regulation of olfaction of volitile attractants.  Required for the suppression of vulval induction in response to food starvation.  Signaling acts through the GPA-5 G-alpha protein subunit.
What are the official names of this protein?
Serpentine receptor class alpha-13, Protein sra-13.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DAPB_CAUVC
Sequence: MSQPVKIAIAGANGRMGRAVAQALEGRSDAVVAARFERPGDAGEGLVARETALAAAEAVIDFTLPEASVALAEEAAANGGPALVIGSTGFSDEQLDRIDAAATKIVIVRSGNYSLGVNMLMGLVRQAAAALPAQDWDIEVFEAHHKRKIDAPSGTALMLGEAAAEGRGINLAKVSDRGRDGVTGPRKDGDIGFSVVRGGGIIGEHSVIFAGESESLTLSHSAIDRGLFARGAIAAAVWVKGKPPGLYDMQDVLGFKK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_CHLTA
Sequence: MVRATGSVASRSRRKRVLKQAKGFWGDRKGHFRQSRSSVMRAMAFNYMHRKDRKGDFRSLWITRLNVASRIHGLSYSRLINGLKQAGIHLNRKMLSEMAIHDPQGFAVVATQAKLALEAAVQG
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ATPE_ROSDO
Sequence: MADTVQFDLVSPERLLASGQVTAVQIPGADGDMTAMAEHAPTITTLRPGLLVTEGPDGTSEYVVTGGFAEITASSISVLAERAIPKAEVTKADHDAMVKEAEEALVKAKEAFANEPGPVDDAAKMLADMVAVGDHITL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.