PharMolix/UniProtQA huggingface dataset:
Protein: RRF_BURM1
Sequence: MSVADIKKGVEQKMQRSIEAFKNDLAKIRTGRAHTGLLDHVQVDYYGSMVPISQVANLTLVDARTIGVQPWEKNMVAKVEKAIREADLGLNPATAGDLIRVPMPPLTEERRRELTKVVKGEGETAKVAIRNLRRDANEALKKLVKDKEISEDDERRAGDDVQKLTDKHVAEIDKLVQTKEAEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIA_FRATT
Sequence: MNKQQLKAYFMLMRLHRPIPILLILWPTLTALVLASHGLPDISYLVIFTIGVVVMRTVGCIINDIADVDFDKHVARTNTRPLTSGQLSIKNAIWLCISLTLVAFICVLFLNLYTILLSFVALFLAILYPFCKRFFAIPQLILGLAFNFGIFMAFSTIQNQIPVEAWIFYIATICWTIAYDTIYALADREFDLEIGIKSSAVLFGNKVFRYILLFNFLSLLLLIILGIYCDFNSFFYLGVVICSLFFVRNYFLYKKLGITNCINAFSANHWIGLIIFIIAVIQYI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPX_LISIN
Sequence: MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCNEIIEEELGISEFVDFGEVPKPQEIRHILSDYVIGQERAKKALAVAVYNHYKRINSNETKEDEVELSKSNICLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQSADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQELIQIDTGNILFIVGGAFDGIEQIVKNRMGEKVIGFGTDNAKLKEDETYLSRVVPEDLLKFGLIPEFIGRLPVIATLEQLDEAALVSILTEPKNALVKQYKRMLELDDVELEFEPTALIEIAKEAIERKTGARGLRSIIEQIMLEVMFEIPSRDDITKCIITEKAARGEEEPQLQLEDGSIIPIKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: LEXA_ARTS2
Sequence: MAAQATGGRATQRSQQSPAKPKGLTVRQKKILETIQRSVNDNGYPPSMREIGDTVGLASLSSVTHQLSQLEKLGYLRRDPKRPRAMEVLMPLTLDEGTAKISGVEKPARLRTIGGLAVSELATATDTAMVPLVGRIAAGGPILADQVVEDVMPLPRQLVGHGELFMLKVTGDSMIDAAICDGDWVVVRRQSDAVNGDIVAALLDDEATVKTFRQRDGHTWLLPQNTQYEPILGDHANIMGKVVSVFRSL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SFMM2_STRLA
Sequence: MTISLENTTVGQNPAGGPPTGKAPLDMEGLAWILFGASAFQYLNAACELNLFELLENKPGLTKPQIGAELGLADRANDILLLGATATGMLTVEDGRYQLATVLAELLKTDDWQRFKDTVGFEQYVCYEGQIDFTESLRSNSNVGLRRVRGSGRDLYHRLHENPQMEQAFYKYMRSWSELANQHLVEVLDLSGTSKLLDCGGGDAVNSIALAQANPHIEAGILEIPPTAPLTEKKIAEAGLSDRITVKPGDMHTDEFPTGYDTVMFAHQLVIWTPEENTALLRKAYNALPEGGRVIIFNSMSNDEGDGPVVAALDSVYFAALPAEGGMIYSWATYEESLTKAGFNPETFQRIDFPGWTPHGVIIATK
What is the function of this protein?
C-methyltransferase that mediates the methylation of tyrosine into 3-methyl-L-tyrosine (3-Me-Tyr) in biosynthesis of saframycin A, a potent antitumor antibiotic that belongs to the tetrahydroisoquinoline family.  Involved in biosynthesis of 3-hydroxy-5-methyl-O-methyltyrosine (3-OH-5-Me-OMe-Tyr), a core structure of saframycin A.
What are the official names of this protein?
L-tyrosine C(3)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: YRAJ_ECOLI
Sequence: MPQRHHQGHKRTPKQLALIIKRCLPMVLTGSGMLCTTANAEEYYFDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDFNHQQLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANFGPWRLRNYSTWTRNDQTSSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYTFTGVQLASDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVSAGAFEINDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDSKEPEFAEATAIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNQHSFHGYQWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEANTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQWGVGYSLNYQYSRYTDQNNDRALSLNLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHNSSLNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGIATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPLPFGALASNDDTGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH
What is the function of this protein?
Part of the yraHIJK fimbrial operon.  Could contribute to adhesion to various surfaces in specific environmental niches.  Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim operon.  Probably involved in the export and assembly of fimbrial subunits across the outer membrane.
What are the official names of this protein?
Outer membrane usher protein YraJ.
What is the protein family that this protein belongs to?
Belongs to the fimbrial export usher family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RL11_CHLFF
Sequence: MSNKKVIKLIKLQIPGGKANPAPPIGPALGAAGVNIMGFCKEFNAATQDRPGDLLPVVITVYSDKTFTFITKQPPVSSLIKKALNLESGSKIPNRNKVGKLTQEQVTAIAEQKMKDMDVVLLESAKRMVEGTARSMGIDVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CH601_MYCVP
Sequence: MSKQIEFNETARRAMEIGVDKLADAVKVTLGPRGRHVVLAKSWGGPTVTNDGVTIAREIDLEDPFENLGAQLVKSVATKTNDVAGDGTTTATVLAQAIIKGGLRNVAAGANPIALGAGISKAADAVSEALLAGATPVTDKKSIAQVATVSSRDEEVGELVGEAMTRVGHDGVVTVEESSTLLTELEITEGVGFDKGFLSAYFVTDFDSQEAVLEDALVLLHREKISSLPDLLPLLEKVAEAGKPLLIIAEDVEGEALSTLVVNAIRKTLKAVAVKAPFFGDRRKAFLDDLAVVTGGQVVNPDVGLVLRDVGLDVLGTARRVVVDKDSTVIVDGGGTQEAIEGRKAQLRAEIEASDSDWDREKLEERLAKLAGGVAVIKVGAATETDLKKRKEAVEDAVHAAKAAVEEGIVVGGGAALVQAGAGLAKLRSELSGDEALGVEVFTAALSSPLYWIATNAGLDGAVVVNKVSELPAGQGFNAATLEYGDLIADGVIDPVKVTRSAVVNAASVARMILTTETAVVEKPEESEDDGHGHGHGHHHGHAH
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYST_SYNY3
Sequence: MTTNLPFSSPSKQLNRFSFWQSISIPWVVTIIYLLLILVLPIAALLVKSASLGLEGFWQIATTPIAISTYNVTFITALAAGLVNGVMGTLVAWVLVRCQFPGKKIVDAMVDLPFALPTSVAGLVLATLYSQTGWVGRFFAPFGIQIAFSRLGVFVAMVFISLPFIVRTLQPVLQELEEEAEEAAWSLGATEFQTFWRVIFPPLIPPILTGIALGFSRAVGEYGSVVLIASNIPFKDLIAPVLVFERLEQYDYPAATVIGAVLLSVSLILLLIINLLQQWGRRYAND
What is the function of this protein?
Part of the ABC transporter complex CysAWTP (TC 3. A. 1. 6. 1) involved in sulfate/thiosulfate import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Sulfate transport system permease protein CysT.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYV_STAES
Sequence: MEMKPKYDPREVEKGRYEEWVSNGYFKPSEDKSKEAYTIVIPPPNVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGISRHDLGREKFLQQAWDWKEEYATFIRQQWAKLGLGLDYSRERFTLDDGLSKAVRKVFVDLYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGNGYIEIATTRPETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIEFGSGAMKVTPAHDPNDFEIGQRHQLENIIVMDEYGKMNDKADKYKGMDRFDCRNQLVKDLKEQDLVIKIEEHTHSVGHSERSGAIVEPYLSTQWFVKMKPLAQRALDNQNTKDRIDFFPGRFENTFNRWMEEIRDWTISRQLWWGHQIPAWYHKDTGEVFVGEEAPEDIENWIQDEDVLDTWFSSALWPFSTLGWPDTNADDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVLLHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVESVWNFINKIWNAARFSLMNIGEDFKVEDIDLSGNLSLADQWILTRLNETISTVTELSDKYEFGEVGRALYNFIWDEFCDWYIEMSKIPMNGEDESQKQTTRSVLSYVLDKIMKMLHPFMPFVTETIWQSLPHHGETIVKANWPTVDQALIFNESKQTMEQLVEIIKSVRQSRVEVNTPLSKAIPILIQTKDEKIKHTLMDNISYLHKFCNPSQLTIDTEIEIPEKAMTTVVVAGKVVLPLEGLIDMDKEIARLEKELDKLQSELDRVDKKLSNENFVNKAPEKIINEEKEKQQHYQEKYNGVKSRIEQLKA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_STRT1
Sequence: MSYEFDENFDVIVVGAGHAGVEASLAAARMGCKVLLATINLEMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKALYAMTMKHTVERQENLTLRQSMVDEILVEDSKVVGVRTATNQKYGAKAVVVTTGTALRGEIIIGDLKYSSGPNNSLASVTLADNLKELGLEIGRFKTGTPPRVKASSINYEETEIQPGDEKPNHFSFLSKDEDYLQDQIPCWLTYTNQESHDIINNNLHRAPMFSGIVKGVGPRYCPSIEDKIVRFADKNRHQLFLEPEGRETEEVYVQGLSTSLPEDVQKELIHSIKGLEKAEMIRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGLVAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTPIGREVGLVDDERWNIFKIKKNQFDRELTRLSKEKLKPIKETNEKIQALGFKPLTDAMTAKEFMRRPEIDYATATQFVGPAAEDLDAKVIELLETEIKYEGYINKALDQVAKMKRMEEKKIPENIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEGNNKARRKVD
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_BACFN
Sequence: MKVIHTIKDLQAELSVLKAQGKKVGLVPTMGALHAGHASLVKRSVNENEVTVVSVFVNPTQFNDKNDLVKYPRTLDADCKLLEACGATYAFAPSVEEMYPEPDTRQFSYAPLDTVMEGAFRPGHFNGVCQIVSKLFEAVKPHRAYFGEKDFQQLAIIREMVRQMQFDLEIVGCPIVREEDGLALSSRNARLSAEERENALKISQTLFKSRTFAATHTVSETLKFVEDAIAAVPGLRLEYFEIVDGNTLQKVDNWNQTSYVVGCITVFCGDVRLIDNIKYKES
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D39U1_MOUSE
Sequence: MRVLVGGGTGFIGTAVTQLLRGRGHEVKLVSRQPGPGRITWSELSESGLPLCDVVINLAGENILNPLRRWNETFQKEVLTSRLDTTHLLAKAITETAHPPQAWILVTGVAYYQPSLTKEYDEDSPGGNFDFFSNLVTKWEAAARLPGESTRQVVVRSGVVLGRGGGAISHMLLPFRLGLGGPIGSGRQFFPWIHIGDLAGILNYALEANHVQGVLNGVAPASTTTNAEFAQALGAALGRPAFIPVPSTVVRAVFGERAIMLLEGQKVVPRRTLATGYQYSFPELRAALKDVVA
What is the function of this protein?
Putative NADP-dependent oxidoreductase.
What are the official names of this protein?
Epimerase family protein SDR39U1, Short-chain dehydrogenase/reductase family 39U member 1.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.
Protein: EIF3M_AEDAE
Sequence: MQGPAVFIDAEIDDQAQELRKFFKSLGAEISEEKSSKGIEDDLHKIIGVCDVCFKDGTQHTLEEIDAVLNSVVSIIVSIPLERGENLILAFCEKMTRAPDSNLARVCLQSLWRLFSNLEPTSPLRYHVYYHLVQVAKRADQVKEVFSGVDQLKSQFSQCPPSNEQMQKLYRLLHDVLKDTNSELASKVMIELLGTYTAENASYAREDAMKCIVTALADPNTFLLDPLLSLKPVRFLEGELIHDLLSVFVSEKLPSYLQFYKNHKEFVNSQGLNHEQNIKKMRLLSFMQLAESNPEMTFQQLQDELQIGENEVEPFIIEVLKTKLVRARMDQKARKVHISSTMHRTFGRPQWQQLRDLLHAWKANLTLVQENMKSVSEAQIELAHKQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_GLOVI
Sequence: MGELGTMGGTRDFLPDEMIRREYVIDTLKTIFRKYGFEPLETPAIERWETLAGKYGEEGEKLIYHVVSSGSLGTLKAGERTEHALRYDLTVPLARVVGMYGDQMVADPADPKKQTRRLPRPFKRYQIQPVWRGDRPGEGRYREFHQCDADVVGSTSPLVETELIALTVEAFKALGFADFTVKINHRQLLKGLIEQAGIAPTKEATVLTSIDKLDKLPPEKVRLELAGKGLNADQLDALFQVIALEGTSEQVLEGARSLLAGSEAAQRGIGELTKLLHYLEALGVDSAYYRIDLALARGLDYYTGTIFETVSAAKVGSVGAGGRYDRLIYDLSGGKADLPACGTSFGLDRILAAMDQLGLFASLRRAGEVLVLHFGDPGVSQVCFELVRGLREAGVRAELGYHEEPFTPNGMRQQLGYANEKGFAYAVIVGPDEMAQGQAALRDLTTRRQEKIPLATAGQLIAGRLRS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7A_AQUAE
Sequence: MPRKGPVPPREIPPDPKYGDVLVQKLINKVMKDGKKSVAEWIVYTALEEAAKEVNMHPVELLHKVIEKLKPEWEVRPTRVGGATYQVPIEVPERRQISLAIKWLVQAARERPRGREQYTMIERLKAELLDALNERGGAYKKKEETHRMAHANMVFSHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity).
What are the official names of this protein?
30S ribosomal protein S7-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PSD_PHOV8
Sequence: MNRLKKLKKIRLHREGTSILIVSAILLIGINALLFWGIECKIPFYIFATASIVVYLLMVNFFRCPIRLFEHDTEKIVVAPADGRIVVIEEVDEHEYFHDRRLMISIFMSIVNVHANWYPVDGVVKHVDHHNGKFMKAWLPKASTENERSMVVIETPEGHTVMARQIAGAIARRIVTYAEVGEDCYIDEHMGFIKFGSRVDVYLPLGTEVCVKMGQATVGNETVIAKLK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EFTS_NITSB
Sequence: MAISAAQVKELRERTGAGMMDCKKALQEANGDMDKAIEILRKKGIAKAAKKADRVASEGTIAVQVSEDYKCATIVEVNSETDFVAQNENFKSLVEKVKGHIAQSAVESVEELYKTPIDNVIFEEYMKAEIAKIGENIVVRRFDKICVEGPGVVNGYLHMGGKIGVIVAASCDKEDVCASLKDLLKDVAMHIAAMNPRYLDEASIPAEVIEKEKEIAAAQLEKEGKPANIIEKIIPGKIKKFVEENTLLGQKFVKDDKKSVKQVIDEAAKAAGGSAKIIGFIRYELGEGIEKKEEDFAAEVAAQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADA2_YEAST
Sequence: MSNKFHCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDYRIIETNSYPILCPDWGADEELQLIKGAQTLGLGNWQDIADHIGSRGKEEVKEHYLKYYLESKYYPIPDITQNIHVPQDEFLEQRRHRIESFRERPLEPPRKPMASVPSCHEVQGFMPGRLEFETEFENEAEGPVKDMVFEPDDQPLDIELKFAILDIYNSRLTTRAEKKRLLFENHLMDYRKLQAIDKKRSKEAKELYNRIKPFARVMTAQDFEEFSKDILEELHCRARIQQLQEWRSNGLTTLEAGLKYERDKQARISSFEKFGASTAASLSEGNSRYRSNSAHRSNAEYSQNYSENGGRKKNMTISDIQHAPDYALLSNDEQQLCIQLKILPKPYLVLKEVMFRELLKTGGNLSKSACRELLNIDPIKANRIYDFFQSQNWM
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA.  SAGA is involved in RNA polymerase II-dependent transcriptional regulation of approximately 10% of yeast genes.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8).  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  SALSA, an altered form of SAGA, may be involved in positive transcriptional regulation.  SLIK is proposed to have partly overlapping functions with SAGA.  It preferentially acetylates methylated histone H3, at least after activation at the GAL1-10 locus.  ADA preferentially acetylates nucleosomal histones H3 (to form H3K14ac and H3K18ac) and H2B.
What are the official names of this protein?
Transcriptional adapter 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACP_DESDA
Sequence: MSDVAEKVKKIIVDQLGVSADEVKPEASFVEDLGADSLDLTELIMAMEEEFEVEIADEDAQKILKVQDAIAYIEEKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAT42_CAEEL
Sequence: MSSRSSWSSTEQINRTISSRADDLPPQPRRLEVVSKQATRVTALSTKLEWKIEQFEKLMKLIKNGSNLISRMFSVPDAPTVCWELHVYPNGKRDEDVNNVSFFLRQVGLARGEEPIMTEFQIYALDANNQRVSVCRDTKDFTNQQGRGKFQVSRDKMLGALRSDGTLFLICEVEYFPPGSKISVEPVVDEDVSTEEQEEMPEVIVRANNRSMWEDELFTDCVIHVGNKHIKAHRCILGQNSPVFKSMFSSPNMIEAQKGEIHIEDAKYDSVRAMVEFMYTGATESLESQGNIDEILAIADKYEVLMLKDQCERLIAQTINLKNVTQIAMFSDTYTADYLKSAVIRFLTTHHRVVIKTQDWISLKKSRHELANELLEAVLSTDQDDDDVTSNIPISVSPPPARKRLRRSAK
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
BTB and MATH domain-containing protein 42.
Protein: RR19_CYAM1
Sequence: MSRSVKKGAYVHVRLLKKIERLNQKGEKQIIKTWARSSTIVPAMVGHTLAVYNGKTHIPVFITDALVGHKLGEFAPTRNFRSHVKGDRKIRKSI
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL25_KOCRD
Sequence: MVDVITIPATLRTEFGKGYARRVRANDKIPAVIYGHGAEPLHVILPGHEMMLASRNSNAVLDINVDGEGHLAMIKEVQRHAVRPEILHIDLLTVRRGERVEVEIPVHVEGEVAPTAIHNVEENVLVVEADALKVPEYLTVDITDLEVGEHVYAKDVTLPGNVTLVSDPELLVVNVSEPVEQDLGEESETEEEGAEGEKPAESTGEEPGDDE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: CIAO1_PICST
Sequence: MVSLIKSIKAHSDKAWSVSAHKTVPLLATASTDKTSKIYKLSVKQNFPQVAQLEDTHKRSVRAVSFKPPLPGVESNFLDLPALASGSFDSTISIWGIDEPETEILSSPRNEWNLMAIIEGHENEIKAVGWNHNGSLLASCSRDKTVWIWETDPETLEEFECISVLNDHQHDIKHVVWHPHQNLLASSSYDDTIRLYKQDLDDDDWSCVGVLNGHEGTVWCSQFEDNHRHQESNESSNRSKIRLVSVSDDMTARIWSKYIPSSIKHKSEMVWEQESILPPVHQYPIYSVAWSAQSGKIATVGSDGKIVIYIEGDDNSWSIDSVKESAHGVHEINSIIWALLDDQSEVLVTAGDDGCVNIWKP
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Preferentially localized to the nucleus.
Protein: NRDR_VIBC3
Sequence: MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELVMPRVIKSNGNREPFDEEKMIGGLQRALEKRPVSADAIELAISTIKSKLRATGEREVPSKLIGNLVMEQLKVLDKVAYIRFASVYRSFEDVREFGEEIAKLQD
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PFKAP_RAT
Sequence: MSDQDSSTSSTSFPKYLEHLSGDGKAIGVLTSGGDAQGMNAAVRAVVRMGIYTGAKVYFIYEGYQGMVDGGSNIVEAKWECVSSILQVGGTIIGSARCQAFRSREGRLKAACNLVRLGITNLCVIGGDGSLTGANLFRKEWSGLLEELAKNGEIDSDTVKKHAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEEMCLKLSENRARKKRLNIIIVSEGAIDTQNKPITSEKIKELVVTNLGFDTRVTILGHVQRGGTPSAFDRILASRMGVEAVLALLEATPETPACVVSLRGNQAVRLPLMECVQMTQDVQKAMDERRFDEAVKLRGRSFEGNLNTYKRLAIKEPDDKIPKSNCNVAIINVGAPAAGMNAAVRSAVRVGIAEGHKMFAIYDGFDGLANGQIKEIGWGDVGGWTGQGGSILGTKRTLPGKYLEKIAEQMHSKNINALLIIGGFEAYLGLLELAAARNKHEAFCVPMVMVPATVSNNVPGSDFSIGADTALNTITDTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEQFDIRDLQSNVMHLTEKMKTSIQRGLVLRNENCSVNYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSPFDRNFGTKISAKAMEWISAKLKGSHGTGKKFVSDDSICVLGIQKRDLLFKPVAELRKATDFEHRIPKQQWWLKLRPIMKILAKYEASYDMSDVGKLEPVHNHGELSAI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, platelet type, ATP-PFK, PFK-P, 6-phosphofructokinase type C, Phosphofructo-1-kinase isozyme C, PFK-C, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.