PharMolix/UniProtQA huggingface dataset:
Protein: PSBE_HUPLU
Sequence: MSGNTGERPFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQEIPLITGRFNSLEQVDEFTRSL
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TLPB_BACSU
Sequence: MGKFIQWIKQPSISKPLIAAFLAVLILPVGVLAYFSYQSAWNALDRELISSAKGNVEELNSTLQNKLEDKVKAIDYYSETVDKDILLGKNKTLLKEKFKQYTTLNDDVGAIYAASEDKKLYKYPDSGVPKGFDPTGRDWYKQAVAEKGQAVFSEPYTDEATGDIVVTISKQLKDGSGVIALDLNLDEVLTASKRIKIGKEGFAFITTGNKKYIAHPTIKPGTTGSGDWTNQVYSKKEGSFEYTFEGKEKKMAFTTNKLTGWKIAGTYFVSELQDASSPVLNTAVIILCVSIVIGGILILYIIRAITKPLRKLVSTSAKISSGDLTEVIDIHSKNEFGQLGESFNEMSASLRSVIGVIQTSVENVASSSEELTASAAQTSKATEHITLAIEQFSDGNEAQSEKLETSSNHLSQMNEGISKVAQASSTITKSSIQSSEAAGSGEKLVEHTVGQMKTIDQSVQKAEAVVKGLETKSQDITSILNVINGIADQTNLLALNAAIEAARAGEYGRGFSVVAEEVRKLAVQSADSAKEIEGLIQEIVREISTSLSMFQSVNHEVKEGLQITDQTAESFKQIYEMTTQISGELQNLNATVEQLSAGSQEVSSAVEDISAVAKESSAGIQDIAASAEEQLASMEEISSSAETLANMAEELQDITKKFKIES
What is the function of this protein?
Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.  All amino acids serve as attractants in B. subtilis, they appear to cause an increase in the turnover methyl groups, leading to methylation of an unidentified acceptor, while repellents have been shown to cause a decrease in methyl group turnover.  The methyl groups are added by a methyltransferase and removed by a methylesterase.
What are the official names of this protein?
Methyl-accepting chemotaxis protein TlpB.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECR_LACAC
Sequence: MQYPLPIAHLIDAYMKLPGIGEKTATRLAFYTMDMPQEDVEDFSKALIQVKQDIHQCPICGNITEKEICDICSNPNRDQTTIMVVEQPKDLMALEEMGEYDGLYHVLHGVLSPMDGIGPEEVNIKSLITRLQKNDDVKEVILALNSTPEGESTSMYISKLIKPAGIKVTRLAAGLSVGSDIEYANSITLKRAVQGRTTL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MINE_BRUA4
Sequence: MSLFRFFSKPASAPQARERLQVLLAHERASHEHSDLVAVLREEILAVIAKHIQIDRDKVSVKMDRGDQMSTLEVDIELPLKTKAKVRAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RS3_ACIBS
Sequence: MGQKVHPVGIRLGVVKRHNANWYANPKQYAEYLLKDLQVREFLTKKLKNAMVSNILIERPSGAAKVTISTARPGIVIGKKGEDIEKLQRELTNIMGVPAQVSINEIDRPDLDARLVAEAIASQLEKRVMFRRAMKRAVQNTMRAGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATMRAETTYGTIGVKVWIFRGEILGGMKQVMNPAPAEERPAKRGRGRGEGQERRGRRGDRAADKGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: SYA_RHOPB
Sequence: MSGVNEIRSAFLNYFGKDGHEIVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGVEKRANHRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKDHAIELAWNLITKEFGLPKERLLVTVFSEDDEAFALWKKIAGLPDSKIIRIPTSDNFWQMGDTGPCGPCSEIFFDHGDHIPGGPPGSPEEDGDRFIEIWNLVFMQFDQIAPGQRNPLPKPSIDTGMGLERIAAVLQGKHDNYDIDLFQALIRAIAELTGADPKGEHKASLRVIADHLRASSFLIADGVLPSNEGRGYVLRRIMRRAMRHGQLLGATEPLMWRLVWALVREMGQAYPELVRAEPMIEETLRLEETRFRKTLDRGLIILDEKSSTLKKGDMFDGETAFTLYDTYGFPLDLTQDALRNRGISVDIASFTDAMDRQRAKARASWAGSGDTATETVWFGLREQLGATEFLGYETETAEGVVAALVKDGQKVDQLKVGEAGAIVLNQTPFYAESGGQVGDTGVMTGEGVRFRVTETQKKAHDLFVHLGTVEQGTLTPDTALLLEVDHTRRSSIRANHSATHLLHEALRQVLGDHIAQKGSLVAEDRLRFDFVHQKPISADELRRVEDIANEVVLENDEVTTRLMAVDDAREAGARALFGEKYGDEVRVVTMGKSARQHGSNALGWSVELCGGTHVRRTGDIGLISITGESAVASGVRRIEALTGRFARQSANAAIDTAKATAAELRTSVDDMPARVAALMDERKKLERELAEARKKLAMGGGGAAAANGEAGVREVGGVKLLARAVEGIEIKDLKSLVDQGKKQLGSGVIALVATSADGKGSIVVGVTPDLVARFSAVDLVRKASEVLGGKGGGGKPDMAQAGGPDGSKAQAALDAIAEAIGG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLB6_SCHPO
Sequence: MYFQSFYFLALLLATAVYGQVASPELHSLSRRNWKKPPPFPSTNASYAPVIRSCDSSEIMVNSLPRGELPDLENDFIEKRLSNANEALTTFLQSKNTTADLDLSSIVGDNGPRLGIAVSGGGWRSMLFGGGALAALDSRSNETTLGGLLQSAHYITGADGGSWLLSSLAVNEFRTIQNISKSIWYTRLGIFFIEETHFGDLKNYYTNVVDEVNQKAAAGFNVSLTDYWGRAIARHFVGQLRGGPNLTYSSVQNASWFQTAEYPYPLIVTQGLTGGLPDGSNGTATNSSIYEISPYYLTSFDNNVRSYTPTQYLGTNYSNGTAVDGKCVTQFDNVGFLVGTSSTRYNEALIDVSLRQSRMSRRLGFTLRHMRINGSSVSFYPNPYTDATDIAGNATAVSEDIVDTPYLDLFDGGYDGQNIPIWPLLQPERKLDVVFAFDSSGDTSNFWPNGSSLVATYERVTQRASDAVYDVEDFVHVPTPETFVNLGLNANPTFFGCDGRNTTRGDVPVDHNTPPLVVYMPNTPWTMKSNLVDHRYRIANSEIQALIQNGFVATTQDNSTDFASCLACAVVQRSLERRNQSTSAACQQCFSQYCWNGTVDNTPVDDDSKNPTYNPAVKTSSASGVHANILLSFFVLLATLLVTA
What is the function of this protein?
Catalyzes the release of fatty acids from lysophospholipids.
What are the official names of this protein?
Probable lysophospholipase C1786.02, Phospholipase B.
What is the protein family that this protein belongs to?
Belongs to the lysophospholipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MALT_ECO81
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICDTMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAEFNALRAQVAINDGSPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTSDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFESAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: CEMIP_HUMAN
Sequence: MGAAGRQDFLFKAMLTISWLTLTCFPGATSTVAAGCPDQSPELQPWNPGHDQDHHVHIGQGKTLLLTSSATVYSIHISEGGKLVIKDHDEPIVLRTRHILIDNGGELHAGSALCPFQGNFTIILYGRADEGIQPDPYYGLKYIGVGKGGALELHGQKKLSWTFLNKTLHPGGMAEGGYFFERSWGHRGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDDMARKAMTKLGSKHFLHLGFRHPWSFLTVKGNPSSSVEDHIEYHGHRGSAAARVFKLFQTEHGEYFNVSLSSEWVQDVEWTEWFDHDKVSQTKGGEKISDLWKAHPGKICNRPIDIQATTMDGVNLSTEVVYKKGQDYRFACYDRGRACRSYRVRFLCGKPVRPKLTVTIDTNVNSTILNLEDNVQSWKPGDTLVIASTDYSMYQAEEFQVLPCRSCAPNQVKVAGKPMYLHIGEEIDGVDMRAEVGLLSRNIIVMGEMEDKCYPYRNHICNFFDFDTFGGHIKFALGFKAAHLEGTELKHMGQQLVGQYPIHFHLAGDVDERGGYDPPTYIRDLSIHHTFSRCVTVHGSNGLLIKDVVGYNSLGHCFFTEDGPEERNTFDHCLGLLVKSGTLLPSDRDSKMCKMITEDSYPGYIPKPRQDCNAVSTFWMANPNNNLINCAAAGSEETGFWFIFHHVPTGPSVGMYSPGYSEHIPLGKFYNNRAHSNYRAGMIIDNGVKTTEASAKDKRPFLSIISARYSPHQDADPLKPREPAIIRHFIAYKNQDHGAWLRGGDVWLDSCRFADNGIGLTLASGGTFPYDDGSKQEIKNSLFVGESGNVGTEMMDNRIWGPGGLDHSGRTLPIGQNFPIRGIQLYDGPINIQNCTFRKFVALEGRHTSALAFRLNNAWQSCPHNNVTGIAFEDVPITSRVFFGEPGPWFNQLDMDGDKTSVFHDVDGSVSEYPGSYLTKNDNWLVRHPDCINVPDWRGAICSGCYAQMYIQAYKTSNLRMKIIKNDFPSHPLYLEGALTRSTHYQQYQPVVTLQKGYTIHWDQTAPAELAIWLINFNKGDWIRVGLCYPRGTTFSILSDVHNRLLKQTSKTGVFVRTLQMDKVEQSYPGRSHYYWDEDSGLLFLKLKAQNEREKFAFCSMKGCERIKIKALIPKNAGVSDCTATAYPKFTERAVVDVPMPKKLFGSQLKTKDHFLEVKMESSKQHFFHLWNDFAYIEVDGKKYPSSEDGIQVVVIDGNQGRVVSHTSFRNSILQGIPWQLFNYVATIPDNSIVLMASKGRYVSRGPWTRVLEKLGADRGLKLKEQMAFVGFKGSFRPIWVTLDTEDHKAKIFQVVPIPVVKKKKL
What is the function of this protein?
Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway.  Binds to hyaluronic acid.  Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes.  Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium.  Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination.  In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manner.  May be involved in hearing.
What are the official names of this protein?
Cell migration-inducing and hyaluronan-binding protein.
What is the protein family that this protein belongs to?
Belongs to the CEMIP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Endoplasmic reticulum. Cell membrane. Membrane, clathrin-coated pit. Secreted. Note=Retained in the endoplasmic reticulum (ER) in a HSPA5/BIP-dependent manner. Colocalized with clathrin heavy chain/CLTC in clathrin-coated vesicles. Strongly detected in the cytoplasm of breast carcinoma cells, whereas poorly detected in adjacent normal epithelial cells, stromal cells, or benign breast tissues. Localized in the nucleus and cytoplasm of colon adenocarcinomas.
Protein: RL22_ALBFT
Sequence: METRATLRGVRLSVDKGRLVADLIRGKKVDQALNILQFTQKKAAVIIKKVLESAIANAEHNDGADIDELRVKTIFVEQGASLRRFTARAKGRGNQIRKPTCHVYVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TRPB_STRPN
Sequence: MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVEAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAKKGEAHA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PKS5_DICDI
Sequence: MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK
What is the function of this protein?
Probable polyketide synthase.
What are the official names of this protein?
Probable polyketide synthase 5, dipks5.
Protein: SYT_HELHP
Sequence: MSEVIGIKHNQHIYDLCTADELGITGDSISFDNSQESLAIIRHSCAHLMAQAIKILYPEAQFFVGPVVDEGFYYDFKVNTKISEEDLLVIEAKMKEIAKNAYPITKITLSRKEAQARFAHDELKVAVMSRIPDEKLSIYTQGDFEDLCRGPHLPNTKLLEHFKLTKIAGAYLGGDENAQMLIRIYGIAFADKQSLKDYLFTLEEAKKRDHRKLGQEMGLFTFDEEIGAGLPIWLPKGARLRHNIEHLLTQALKERGYEPVRGPEILKSDVWKKSGHYSNYKENMYFTIIDEQEYGIKPMNCVGHIKVYQSSPRSYRELPLRFYEYGIVHRHERSGVLHGLLRVREFTQDDAHIFCMTSQIKSEVNQILDFTKGIMNAFGFHYEMELSTRPQKSIGNDEVWENATAALKSALEENHISYQIDEGGGAFYGPKIDIKITDALKRKWQCGTIQIDMNLPERFELSYTDEHNVQVQPVMIHRAILGSFERFVAILTEHFGGEFPLFIAPTQVILIPIGEAQLEYARILRDKIITQSGAYAELMDKNESLSKKIRLAEKQRVPLIVVIGAKEVESKILAIRDRREKSQYELPEEAFIATLKTKIGEVSF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M11H1_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKIIGGLKTAVKGALKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKRILGPVISTIGGVLGGLLKNLG
What is the function of this protein?
Maximin-H1 shows antibacterial activity against both Gram-positive and Gram-negative bacteria.  It shows also antimicrobial activity against the fungus C. albicans.  Shows strong hemolytic activity.
What are the official names of this protein?
Maximins 11/H1.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURT_ACTPJ
Sequence: MTTIGTPLRPNATKVMMLGSGELGKEVVIELQRLGVEVIAVDRYENAPAQQVAHRAYTISMLDGAALRALAEKEKPDFIVPEVEAIATATLVELEQEGYNVVPTAKATQLTMNREGIRRLAAEELGLKTSPYRFVDNLEDFKQAVAEIGIPCVVKPIMSSSGHGQSVIKSEDQIQQAWDYSQEGGRAGGGRVIVEGFIKFDYEITQLTVRHVNGTSFLAPIGHRQEDGDYRESWQPQAMSDLALKRAQETAERITTALGGRGIFGVELFVCGDEIIFNEVSPRPHDTGMVTMASQELSQFALHARAILGLPISEIYQISPAASKAIVVEGKSNNMTFGNLDKVLEEIGTNIRLFGKGEVNGHRRLGVILARDENTEKALAKAERAYAKLAVQL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RS14_EHRCR
Sequence: MSRKSVIQRNLKRISICNRLKNKREELKAIIKDQSISMNDRFLAQVKLSKLPRDSSYIRIRNRCLITGRPRGCYRKFKVSRIVLRQLGSIGQIPGLTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: TRPC_THEVO
Sequence: MNYDSVYKSNKLRSFPYSRRRGIISLKERIIELNRSGKRGVIAEYKRRSPSGLKVDYSIEDYLSYVMEHRIAGLSILTEPSFFNGSFQDVVVAHRYNIPILVKDFVPDSEFVDYGFNAGGDAVLVILDFLDYESIKRIVERAADLGMDVLEEFHNQDALKRQYIRDNVMIGYNRRDLTNLLMDEKIPDFSGEVRILESGISIDNVKNLDLKFQGYLIGTSILKKDGTLEYLEMEGII
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: AFLAP_LYOSH
Sequence: AGTEIVTCYNAGTKVPRGPSAXGGAIDFFN
What is the function of this protein?
Displays antifungal activity against M. arachidicola and P. piricola, but not against R. solani, C. gossypii and C. comatus (PubMed:11556814).  Inhibits mycelial growth in P. piricola with an IC(50) of 70 nM (PubMed:11556814).  Displays very low cell-free translation inhibitory activity in a rabbit reticulocyte lysate system (IC(50)=70 uM) but is able to inhibit HIV-1 reverse transcriptase activity (IC(50)=5. 2 nM) (PubMed:11556814).
What are the official names of this protein?
Antifungal protein Lap.
Protein: RL5_STRMK
Sequence: MSSRLEKFYKDEVVPALMKQFGYTNPMEVPKLVKVTLNMGVGEAATNKKILENAVGDMTKISGQKPVVTKSRVSVASFKIRDGWPIGCKTTLRRHKMYEFLDRLINISLPRVRDFRGVSGRSFDGRGNFNMGVKEQIIFPEIDFDAVDAIRGMDIAITTTAKTDAEAKALLAAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DEF_MYCGA
Sequence: MKSKLKPTNDWLVTDDNPKMREVCTEVKFPLSQEVLDIIDKMLAYVDESFDDNAEKYDIRPGIGIAANQLGLNQRFFYVHFTDFCQKEHRYLLINPEWIDKSLNKAYLAVGEGCLSVPKDKDGYVIRSETVKLKGFDYLTQKDVEISAHGLLAMCLQHEMDHLEGKFYYDSINMMKPYFKKDEWVSIDQKVCDQCK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: MDM12_SCLS1
Sequence: MSIDLNWETLTTGPDGIALAEKIRDFVHAKFQTVTLPRFIKGVKVHTFDFGSIAPEVELKDICDPLPDFYEDLDDDDGGSDEDDEGSNSCQTDEENEAAKTLRERRKMDRVERTANGSSNVSNPPSYTDTRYPGLRSMQASGDNGSPFLGVSTPGIPGGTSNLSYFHSQLASGFSGTQTPLAAVAGAHLPQGWPDRPSPSLHMSALRNQSHTSLSHTASERPMTPPQIADLSQQSIREKASASTLAVSSSTTGPVTRGGATEKTIPEEQTSEGEEPTSPPRRFREPKPEDLQTVFRVRYSGNIRLSLTVDILLDYPMPSFVGIPVRLNITGLSFDGVAVLAYIRKRAHFCFLSPEDAYAAIGADEKEAGGSGGMKMGALLHEIKVESEIGQRENGKQVLKNVGKVEKFVLEQVRRIFEDEFVYPSFWTFLV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component mdm12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: RSMC_SHIDS
Sequence: MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRAHTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLLPVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDAEKFWGEYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHSPKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRAIMTRQAKKG
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.