PharMolix/UniProtQA huggingface dataset:
Protein: HLDE_CAMC1
Sequence: MAKRVKILVVGDLMLDHYIWGSCERISPEAPVQVVKINNETYTLGGAGNVVRNLLSLGANVSVASVLGDDEAGKKIKEKLAELNVKDELILTEKGRESSIKSRIMASHQQVVRIDKESVVKINLEDELVLKVKENLANFKAVLLSDYGKGVLSEKVCQEIINECVKLKIPVLIDPKGSDYSKYKNATLLTPNKKEASEATNLKIKDKAELEKAIKQLKEELNLTYSIITISEEGIALYDDKLHIFAAKAKEVFDVTGAGDTVLATLGYMLANGADIKEAIKIANLAAAVVVAKIGSATASFSEIEQLLNSSFGANFEHKLKSIEELEEILSQKGKKKVVFTNGCFDILHAGHVKYLARARELGDLLVVGLNSDASVKRLKGEARPINSQDDRACVLSGLGFVDYVVIFDEDTPLNLITKIKPDVLVKGADYKGKEVVGSDIVKEVRLIDFVEGKSTTGIIKRIKDAKNDDKK
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: LOLD_BORA1
Sequence: MTDTSLQAALRAEHLSKVYDEGPARIQVLDDVSLTVARGEMVAIVGASGSGKSTLLHILGLLDVPTSGSLVVDGTATEGLSEARKSAVRNRSLGFVYQFHHLLPEFSALDNVAMPLIVRRMDRDQARLQAREVLGLVGLAAREGHYPGQLSGGERQRVALARALVTRPACVLADEPTGNLDRQTAQNMFELLSRVNRESGTAFAIVTHDPELAARADRQLHMANGRLLPG
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PRIL_METAC
Sequence: MQAEKLAYYPFISEASAHVGDLGISLESLLNSRAYRTARARGIERVKEALEGEIKKPPVSEEAQVLSELLSYPFARMLVACVDDQLFTRRYALAEAKAAYTFLRNETPDFLLEFGEDFGISAEIRDSHFSMHFTDYIRFSNSLKEPSWKLTNRQFRAGKIKITKEEFARLLEEAVRERIEQSFPIPEIPPEVSAFCAPYVAEIKEQFEVQKKKFGATDFGAVEPELFPPCISHALANVQGGVNLAHSMRFAMTSFLLNVGMSVEEILNLFNVSPDFDAEKTLYQIEHIAGATGNEYKPPACDTMRTYGNCIGKDGLCAKISHPLGYYERRIFLKNKEREKEEGKEKGNEEKKEKREEHEKKNEKGNEIKEK
What is the function of this protein?
Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase large subunit PriL.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: PHF1_ARATH
Sequence: MEIEEASRESGHVVCGSWIRRPKKVNWVLIAKASKRRGSSVSSPALLNIFSFDPITASLSSSPLATHTLKDSDGDPVAVSVHPGGDYFVCSTSKGGCKLFELVGGATGITILAKELLPLQNAGLQKCMAFSFDGSKLAVGGVDGCLRIMEWPNLSVILDEPKAHKSIRDMDFSLDSEFLATTSTDGSARIWKAEDGFPLSTLERSGDENIELCRFSKDGTKPFLFCAAQRGDTPMVNVYDISTWKKLGFKKLSRKTASTMAVSLDGKYIALGGKDGDVSVAEVKTMEIYHYSKRLHLGQSIASLEFCPSERVMLTTSSEWGEMVTKLTVPKEWKEWQIYALLFCLFMASVIAAYVFFENSDSFWKLPMGKDQKRPKISLFGGSSSTPSEDHSRWNLDL
What is the function of this protein?
Involved in Pi uptake by facilitating the trafficking of PHT1-1/PHT1;1 from the endoplasmic reticulum to the plasma membrane.
What are the official names of this protein?
SEC12-like protein 1, Protein PHOSPHATE TRANSPORTER TRAFFIC FACILITATOR 1, PHF-1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: QRI7_SCHPO
Sequence: MLCLVYNSILCKQRRISLKVLQQFRCWNISKTFLSYRTLTALAIETSCDDTSVSVVRTSDSSSHCQNEIICLNTHRTISKYEAYGGIHPTIVIHEHQKNLAKVIQRTISDAARSGITDFDLIAVTRGPGMIGPLAVGLNTAKGLAVGLQKPLLAVHHMQAHALAVQLEKSIDFPYLNILVSGGHTMLVYSNSLLNHEIIVTTSDIAVGDYLDKCAKYLGIPWDNEMPAAALEQFASPEINSTSYSLKPPIPLNTREKVHSASFSFSGLESYACRIIRKTPLNLSEKKFFAYQLQYAAFQHICQKTLLALKRLDLSKVKYLVCSGGVARNELLKKMLNDTLMVLQFEHQPTDIKLVYPSPDICSDNAAMIGYTAIQMFKAGYTSSFDVEPIRKWPINQILTVEGWLTKKNKKV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine.  Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Involved in mitochondrial genome maintenance.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, Pombe glycoprotease 1, t(6)A37 threonylcarbamoyladenosine biosynthesis protein pgp1, tRNA threonylcarbamoyladenosine biosynthesis protein pgp1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TYSY_MYCUA
Sequence: MPIATPYEDLLRRVLETGTAKSDRTGTGTRSLFGQQIRYDLGCGFPLLTTKKVHFKSVVYELLWFLRGDSNVGWLQQHGVTIWDEWASETGDLGPIYGVQWRSWPTPSGEHIDQISAALELLRTDPDSRRIIVSAWNVGQIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVTEQLRREPRPYPKLSLSQRDSIFDYTYEDVVVQDYDPHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_SHIFL
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CSRP2_RAT
Sequence: MPVWGGGNKCGACGRTVYHAEEVQCDGRTFHRCCFLCMVCRKNLDSTTVAIHDEEIYCKSCYGKKYGPKGYGYGQGAGTLNMDRGERLGIKPESAQPHRPTTNPNTSKFAQKYGGAEKCSRCGDSVYAAEKIIGAGKPWHKNCFRCAKCGKSLESTTLTEKEGEIYCKGCYAKNFGPKGFGYGQGAGALVHAQ
What is the function of this protein?
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation.  Seems to play a role in the development of the embryonic vascular system.
What are the official names of this protein?
Cysteine and glycine-rich protein 2, Cysteine-rich protein 2, CRP2, Smooth muscle cell LIM protein, SmLIM.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIMD1_RAT
Sequence: MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGASNNPEFEETRRVFATKMAKIHLQQQQQQQLLQEEALPRAGRSPINGGNRQGVSSKLAADGAAKPPLAVPTVAPGLATTTMAVQSSYPPQEQRTRPSAHGARPGSQNCGSREGPVSSQRPALHGLGPCEDPSCLTHGDYYDNFSLASPQWGDKPEESPSMSLSVGSGWPGCPGNDSLSHRSCGDSHPYHPQLSMCSGRSFESGQDSGIGGHSSEKPTGLWSTASSQRVNLGFSSTGLENGTPAQPKGTTVSAPMVPSSTSQGACLRRDSSLGYEAPGRVFKPLVDTQPWLQDGPKSYLSVSAPLSSTTSKDNAQTGMTAGLDPKLGCVESGTSPKPSPTSNVHPVMSAPSELSCKESPPSWSTDSSLGPVLPESPTPSRVRLPCQTLTPGPELGPSTAELKLEALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKGPSPASLHQHHF
What is the function of this protein?
Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration.  Positively regulates microRNA (miRNA)-mediated gene silencing and is essential for P-body formation and integrity.  Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A.  Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription.  Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1.  Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements.  Regulates osteoblast development, function, differentiation and stress osteoclastogenesis.  Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1) and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts.  May act as a tumor suppressor by inhibiting cell proliferation (By similarity).
What are the official names of this protein?
LIM domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Cell junction, adherens junction. Cell junction, focal adhesion. Note=Shuttles between cytoplasm and nucleus but is localized predominantly to the cytoplasm. Found in the nucleus but not nucleoli. Colocalizes with VCL in the focal adhesions (By similarity).
Protein: MA20_PINMA
Sequence: YQRXSRYYYYXGPPDDIDDRY
What is the function of this protein?
May be specifically involved in the formation of the nacreous layer.
What are the official names of this protein?
Conchiolin protein p20.
What is the protein family that this protein belongs to?
Belongs to the N16 matrix protein family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: COR11_PAPSO
Sequence: MESNGVPMITLSSGIRMPALGMGTAETMVKGTEREKLAFLKAIEVGYRHFDTAAAYQTEECLGEAIAEALQLGLIKSRDELFITSKLWCADAHADLVLPALQNSLRNLKLDYLDLYLIHHPVSLKPGKFVNEIPKDHILPMDYKSVWAAMEECQTLGFTRAIGVCNFSCKRLQELMETANSPPVVNQVEMSPTLHQKNLREYCKANNIMITAHSVLGAVGAAWGTNAVMHSKVLHQIAVARGKSVAQVSMRWVYQQGASLVVKSFNEARMKENLKIFDWELTAEDMEKISEIPQSRTSSAAFLLSPTGPFKTEEEFWDEKD
What is the function of this protein?
Reduces codeinone to codeine in the penultimate step in morphine biosynthesis.  Can use morphinone, hydrocodone and hydromorphone as substrate during reductive reaction with NADPH as cofactor, and morphine and dihydrocodeine as substrate during oxidative reaction with NADP as cofactor.
What are the official names of this protein?
NADPH-dependent codeinone reductase 1-1.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Note=Present in the cytosolic part of laticifer cells that secrete latex.
Protein: PUR9_CLOD6
Sequence: MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGVNVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNLYDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDTMTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQNGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHANSCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFEPEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKPTDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFTGAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: NUON1_CHLT3
Sequence: MLEDFLKVMPLMTASGISILLILVEAATKNARITRLFAILGFLLVFLSLPFSPSEPDFAFSNMLQSGGFFTYTATVFSIGGLLITLISDKYLEMEDAHHGEYYIILFMAVVGMMLMSAAANLTILFIGLELMSIALYVLAGIMRDDQRSNEAAIKYFLLGAFASGIFLYGIALIYGATGTLYIPQISDHLAKNGFDTLFLSGIALLMIGLLFKVAAVPFHQWSPDVYEGSPTVATAFMATGAKAAALSSMILVGISIAPILETFTAWPTAIAMIATLTMFFGNIAALIQTNLKRMFAYSSIAHAGYMLIGIATGTDSGYAGVLYYIFLYTLMNIGAFGIIILVEQKHQFSELADYEGFFSRAPLLAFLMAMFMFSLAGIPPFGGFIAKYNVFSAAVQADMTWLAVAGVIASAVSVSYYLRVVIAMFMKDTKKQKLNPDPTATATIALVAFLVLLFGIYPSLLIEYTQHALAFAMK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 1, NADH dehydrogenase I subunit N 1, NDH-1 subunit N 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU3C_ARATH
Sequence: MFLLYEYDIFWAFLLISSAIPVLAFLISGVLSPIRKGPEKLSSYESGIEPIGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSAFIEAFIFVLILILGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MUTL_STRPI
Sequence: MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKYMKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSAKKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPDALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLTLFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTKKVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENHTSLRELGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: CD28_HUMAN
Sequence: MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLDSAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS
What is the function of this protein?
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.  Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933).  Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).
What are the official names of this protein?
T-cell-specific surface glycoprotein CD28, TP44.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Cell surface.
Protein: SURE_SHIDS
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHFGFPALAVSLDGHNHYDTAAAVTCSILRALCEEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLRVDLTAHSAQDVVSDWLNSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_FRACC
Sequence: MPIRVAIVSPEQEVWSGDADMVVARTTDGDLGVLPGHVPLLGLLAPGGTVRVKTGGREISASVDGGFISVTHQGVSILAETAKLT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCNJ_MOUSE
Sequence: MELEGQWWRGQLAADIHQALRYKELKLPSYKGQSPQLNLRRYFADLIAIVSNRFTLCPPARHLAVYLLDLFMDRYDISIQQLHLVALSCLLLASKFEEKEDSVPKLEQLNSLGCMTNMNLVLTKQTLLHMELLLLETFQWNLCLPTAAHFIEYYLSEAVHETDLHDGWPMVCLEKTKLYMAKYADYFLEVSLQDYAFLNYAPSLVAAACVASSRIILRLSPTWPTRLHRLTAYSWDFLVQCIERLLLAHDNDVKEANKQRGQSAPQSTQLTVFQTAQPSRPVHFQQPQYLHQSSLQYRHPVSEQPSRQQIVSTTHTSSYTLQTCPAGFQTSVQGLGHMQTGVGMSLAIPVEVKPCLSVSYNRSYQINEHFPCITPCFER
What are the official names of this protein?
Cyclin-J.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin J subfamily.
Protein: DNAK_STRPN
Sequence: MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAEDYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKEEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKENGIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFDDLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDKNGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNEVDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKTKLEALNEKAQGLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RNF13_PONAB
Sequence: MLLSIGMLMLSATQVYTILTVQLFAFLNLLPVEADILAYNFENASQTFDDLPARFGYRLPAEGLKGFLINSKPENACEPIVPPPVKDNSSGTFIVLIRRLDCNFDIKVLNAQRAGYKAAIVHNVDSDDLISMGSNDIEVLKKIDIPSVFIGESSANSLKDEFTYEKGGHLILVPEFSLPLEYYLIPFLIIVGICLILIVIFMITKFVQDRHRARRNRLRKDQLKKLPVHKFKKGDEYDVCAICLDEYEDGDKLRILPCSHAYHCKCVDPWLTKTKKTCPVCKQKVVPSQGDSDSDTDSSQEENEVTEHTPLLRPLASVSAQSFGALSESRSHQNMTESSDYEEDDNEDTDSSDAENEINEHDVVVQLQPNGERDYNIANTV
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates cell proliferation.  Involved in apoptosis regulation.  Mediates ER stress-induced activation of JNK signaling pathway and apoptosis by promoting ERN1 activation and splicing of XBP1 mRNA.  Also involved in protein trafficking and localization.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF13, RING finger protein 13.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Nucleus inner membrane; Single-pass type I membrane protein. Note=Under certain conditions, relocalizes to recycling endosomes and to the inner nuclear membrane.
Protein: RS10_CHLL2
Sequence: MAVQQKIRIKLKSYDHSLVDKWALRIIDVVKQTDAIIFGPIPLPTKAHIYTVNRSPHVDKKSREQFSFSSHKRLIEIINPTTRTIDMLMKLELPSGVDVEIKS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: PURA_ECO45
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPAB5_HUMAN
Sequence: MIIPVRCFTCGKIVGNKWEAYLGLLQAEYTEGDALDALGLKRYCCRRMLLAHVDLIEKLLNYAPLEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and a small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, POLR2L/RBP10 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC5, RNA polymerases I, II, and III subunit ABC5, DNA-directed RNA polymerase III subunit L, RNA polymerase II 7.6 kDa subunit, RPB7.6, RPB10 homolog.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
Protein: TRNH7_ARATH
Sequence: MDKRWSLQGMTALVTGAASGIGYAIVEELAGFGARIHVCDISETLLNQSLREWEKKGFQVSGSVCDVTSRPEREKLMQTVSSLFDGKLNILVNNVGVLRAKPTTEYVADDFTFHISTNLEAAYHFCQLSHPLLKTSGYGSIVFLSSVSGVVSITDCGSLYGLTKGALNQLARNLACEWAKDGIRANAVAPNVVKTAQSQFFLQDVSKKEGLFSRTPLGRSGEPNEVASLVVFLCLPAASYITGQTICIDGGLTVYGFSSQPQA
What are the official names of this protein?
Tropinone reductase homolog At2g29300.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. SDR65C subfamily.