PharMolix/UniProtQA huggingface dataset:
Protein: AZO1_STAHJ
Sequence: MKGLIIVGSAKVGSHTNALAKYLVGQFDTHDLDVDIYDLAERPLNQLDFSGTTPSIDEIKTNIKDFQEKVMAADFLVLGTPNYHGSYSGILKNALDHINMDYVKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDYSKLDDGTLYLDDDQFQLRAKLFVDQIVSFVNNSPYEHLK
What is the function of this protein?
Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines.  Requires NADPH, but not NADH, as an electron donor for its activity (By similarity).
What are the official names of this protein?
FMN-dependent NADPH-azoreductase, NADPH-dependent flavo-azoreductase, NADPH-flavin azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 2 family.
Protein: MDH_KLEPR
Sequence: SLYDIAPVTPGVAVDLSHIPTDVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAKTRPQACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLF
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: URE3_BURP1
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPETVAFITAALMEAARDGRTVAEVMHYGTTLLTRDDVMEGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_HELPH
Sequence: MKQTTINHSVELVGIGLHKGVPVKLVLEPLGENQGIVFYRSDLGVKLPLKPENIVDTKMATVLGKDNARISTIEHLLSAVHAYGIDNLKISVDNEEIPIMDGSALTYCMLLDEAGIKELDAPKKVMEIKQAIEIREGDKFVKIEPDSQLSLNFTIDFNHPVIAKQAHHFVFSKTAYKEQVAKARTFGFLQEVNYLRSIGLAKGGSLNNCIVLDENSILNKEGLRCEKEFVCHKILDAMGDLMVLGMPVMGKYTSFSGSHKLNSMLVKAILADAKNYEVLIATDPAKEFALQKAFA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: MBHM_ECOLI
Sequence: MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEIVKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTHDHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVASGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNLAVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRGKGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHSWYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRESTQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNIGKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGPRNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKVL
What is the function of this protein?
This is one of three E. coli hydrogenases synthesized in response to different physiological conditions.  HYD2 is involved in hydrogen uptake.
What are the official names of this protein?
Hydrogenase-2 large chain, HYD2, Membrane-bound hydrogenase 2 large subunit, NiFe hydrogenase.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DJC27_MOUSE
Sequence: METNVPKRKEPAKSLRIKVISMGNAEVGKSCIIKRYCEKRFVSKYLATIGIDYGVTKVQVRDREIKVNIFDMAGHPFFFEVRNEFYKDTQGVILVYDVGQKDSFDALDSWLAEMKQELGPHGNMDNIVFVVCANKIDCSKHRCIDESEGRLWAESKGFLYFETSAQTGEGINEMFQTFYLSIVDLCENGGKRPTASSSASFTKEQADTIRRIRNSKDSWEMLGVRPGASREEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK
What is the function of this protein?
GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed.  May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
What are the official names of this protein?
DnaJ homolog subfamily C member 27, Rab and DnaJ domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: GPDA_RHORT
Sequence: MNQIIDHIAVIGGGAWGTALAQTSRRAGRRVTLWAREPEVARAINATHENPDFLPGVSLDPGLHATADLAEALRGAEAVLVVCPAQALRPVLTTARPLWPGRAPMVICAKGVEQGSGARMSEVATAVLPEAPLAVLSGPTFAREVAEGRPTAVTLACADGALAEALVLALGTRTFRPYASTDVVGAEIGGAVKNVLAIACGVVEGLGLGDNARAALLTRGLAEITRLGRALGARSETLSGLSGLGDLILTATSMQSRNFSLGFALGQGRTLDQVLGERRSVAEGVHTASAVVALAARWAIEMPICAAIHGVLSGDYDVTSAIESLLSRPLRVEGGSESQIHPTAKTATP
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRA_SHIBS
Sequence: MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAEK
What is the function of this protein?
Although this protein associates with the 30S subunit of the ribosome it is not considered to be a bona fide ribosomal protein.
What are the official names of this protein?
Stationary-phase-induced ribosome-associated protein, SRA, 30S ribosomal protein S22.
What is the protein family that this protein belongs to?
Belongs to the SRA family.
Protein: ENO_LEGPH
Sequence: MHIHKIQAREILDSRGNPTIEADVTLTTGIIGRASVPSGASTGSREACELRDNDPKRYAGKGVQKAVKHVNNEINQALQGLSVEDQENLDRILCQLDNTENKSHLGANAILATSLACARARALSLNQPLYMTLNQGDMMTMPVPMMNILNGGAHADNNVDIQEFMIMPIGAPDFPVALQMGTEIFHVLKSVLKKQGLNTAVGDEGGFAPNIQSNRQALDLLSEAIEKAGFRLGEDIVFALDVAASELFNEGFYHMYSENQKFDSHQLIEYYANLISSYPIVSIEDGLDEKDWSGWKQLTTHLGNKVQLVGDDLFVTNPKILREGIAQGIANAILIKVNQIGTLSETRQAIKLAYDNGYRCVMSHRSGETEDTFIADLAVASGCGQIKTGSLCRTDRTAKYNQLLRINELASLPYAGKNILKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: CAPSP_ASFWA
Sequence: MAATRAAPKTASKKEHQYCLLDSQEKRHGHYPFSFELKPYGQTGANIIGVQGSLTHVIKMTVFPFMIPFPLQKIHIDDFIGGRVYLFFKELDVQAISDVNGMQYHFEFKVVPVSSNQVELLPVNNKYKFTYAIPEVQYLTPIFYDLSGPLNFPLDTLSVHVDSLTNHIQLPIQNHNLTTGDRVFISGYKHLQTIELCKNNKIFIKCIPPLSSEKIKLYIPKNRIRIPLYFKSLKNV
What is the function of this protein?
Forms the penton at the fivefold vertices of the icosahedral capsid (By similarity).  Together with the minor capsid proteins (p17, p49, and M1249L), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid (By similarity).
What are the official names of this protein?
Penton protein H240R, pH240R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus H240R family.
What are the subcellular locations of this protein?
Virion.
Protein: GCH4_CALBD
Sequence: MIDVQSQKDQRGISIQKVGIKDLNWPIVVMDRENKTQTTIAKIIAAAELKGDIRGTHMSRFIEAIDELKVVGPKEIEKLLDRIKEKLNSEKAYIRFDFPYFINKRTPVTATLSPLKVDCYFEAEKDQKFDLKVGVIVPVHTLCPCSKEISEYGAHNQRAYVTIEVRMKKFMWIEELVEIAEASASCPLYSILKRPDEKWVTERAYQNPRFVEDLLREVVLKMKEDGRIKWYKVFVESIESIHNHNAFAYIEGEITK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: 3609L_ASFWA
Sequence: MVLSLQTLAKKVLAGQRPTKCHPHFLKCYGLWWHNGPMIFDQNQKKIWSPIFTDGVHINAALVKAVAENNYDLIKLFTEWGANIDYSLLSVNTERTRDLCRELGAKEQLKQEEVLYYFNIIKRNLTSSNIILCHEVFSHNPILETINRTKLRGIIYEQLEALMENTDILSELLTKYWYGIAIEFNLTKAIHYFYQRYVHLHQWRLMYALFYNNVCDLHELYAKEKIRMDMDEMLKWACRKNYNYLTIYYCCIVLGADINQAMFHSIQFYNIGNMFFCIDLGANAIEEGKTLALQKDKSFIASLLSINCYSMNDSLSLKETDPEVIKRMLKDYHSKNMSIAHKYYIKHGFNDI
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-9L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PETD_ORYSA
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPTGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIEKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS18_TROWT
Sequence: MGYRAKGRRQPKADSVVAPPKRVSIKGLDYKDLASLKRFLSDRGKIRARRVTGASIQQQRQIAKAIKNAREMGVIPFKSGVSR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PETN_SPIOL
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YUBL_SALCH
Sequence: MRMSEYFRILQGLPDGSFTREQAEAVAAQYRNVFIEDDQGTHFRLVVRQDGTLIWRSWNFEDCAGYWMNQYIRDFGILK
What are the official names of this protein?
UPF0401 protein YubL.
What is the protein family that this protein belongs to?
Belongs to the UPF0401 family.
Protein: IDI2_CAMAC
Sequence: MSAASHIHSVACRLSSSFLASPKLKLHPRLSFFFHSSSFRNHIITRSVFCSSSHLSVRVSSYHSSVAAKATTSAMGDTATDAGMDAVQRRLMFEDECILVDENDHVVGHDTKYNCHLMEKIESDNLLHRAFSVFLFNSKYELLLQQRSATKVTFPLVWTNTCCSHPRYRESELVDENALGVRNAAQRKLLDELGIPAEDVPVDQFIPLGRMLYKAPSDGKWGEHELDYLLFIIRDVNVHPNPDEVADVKYVNQDQLKDLLRKVDAGEEGLKLSPWFRLVVENFLFKWWDHVEKGTLQDATDMKTIHKLT
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase II, Isopentenyl pyrophosphate isomerase II, IPP isomerase II.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
Protein: TCPB_ENCCU
Sequence: MNIFSHANLGTTEERGDDAKRTILAGTDIVGDILKTTLGPKGMLKMLKGQHVNVTNDGAFILNNLMIDSPSARILIGSSTGQDWEEGDGTTSVAILASLLVKEAGKLEMHPTKILRGYRMAQAKCEEILSSISFEATKEDLLKLVRTTLCSKVLRYDLERFCEICVNAVEKLEGRNDLNLIQIIKCSGKLEDSYLDDGFLLKKDIRIDDVVNPRVLIANTSMDQDKIKVFGAKINVNSVGELEEMEKAEKIKIKGKVERISQNGVNVFVNRQLVYDYPLQLLRMKGIQAIEHADFDGVERLNNVLGGKILSTFDNMDESCYGTCESIRNVHVGNERMIKFSGVRSGASTIVLCGSSKEMLDEAERSVHDALCVLAKIKEDPRVIYGGGSSEMAMAVGLNKYAMEVPGAESDAILAFSSALQQIPKILADNGGYNGESIKASLRAEHNSGRTSYGVNVRNGSIGCMKEAGVVDSLRIKHRVVTAASETAQMIIKCDAIVKCKPRERTRE
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.
What are the official names of this protein?
T-complex protein 1 subunit beta, TCP-1-beta, CCT-beta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1683_SYNE7
Sequence: MATLRIRLQVPKKYRDQPLMGDVLASCQLQFNILAAHLGPNREEDGWFDVMLTGTSEDITAALAVLRDRDIELWSDTEDEF
What is the function of this protein?
May have a regulatory function.
What are the official names of this protein?
Uncharacterized protein Synpcc7942_1683, ORF 81.
What is the protein family that this protein belongs to?
To Synechocystis PCC 6803 ssr2439.
Protein: DLTC_STAAC
Sequence: MEFREQVLNLLAEVAENDIVKENPDVEIFEEGIIDSFQTVGLLLEIQNKLDIEVSIMDFDRDEWATPNKIVEALEELR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPSA_RALSO
Sequence: MFVSIPNIRKAVVSLSVVPLLAACAFAPGMRFDPQRPLDPADNASVPKITPITPDLVRAGQTQAQVQASHENADVGPLLAKATPYRIGTGDILSIVVWDHPELVFPTQTYSIGSTYDLASFGGAPSVSGYVVSTGGDIQFPYAGVIKVAGKTQNEVRDEISRGIARVVKDPQVTVRVLAYRSQRVYVDGEVKTPGQQSIDDVPMTLVEALNRAGGINTTTGDNSRIRLTRGGKQWTLSMPALMQQGIDPANILLRGGDIVRVEQREDSKVFVTGEVVRPSTVLPRNGRLTLSEALGEAGGVSPVSSDPRNVYVIRRAAEGEPQVYHLDAKSPVALALAEGFELKPKDVVYVDAGSLVRWSRVINLLVPTATPLIGAAAVAK
What is the function of this protein?
Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor.
What are the official names of this protein?
EPS I polysaccharide export outer membrane protein EpsA.
What is the protein family that this protein belongs to?
Belongs to the BexD/CtrA/VexA family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: RUVB_RHOCS
Sequence: MSPPDRPQRLVEQDRIGGDAAEASIRPLSLAEFIGQRQVRENLSVFIQAARGRKEALDHVLLFGPPGLGKTTLAQIVAKELNVGFRATSGPVIAKAGDLAALLTNLQPHDVLFIDEIHRLSPAVEEILYPAMEDFQLDLIIGEGPAARSVRIDLPPFTLVGATTRSGLITRPLRERFGIPLRMQFYEPEELQLIVARGARILGMELTGEGALEIARRSRGTPRVAGRLLRRVRDICGVAGLAVVDAAAAGGALTRLEVDRLGFDAMDRRYLRCIADNYGGGPVGVETLGAALGEQRDVLEETIEPYLIQQGLLQRTPRGRLLTDSGYRYLGLPPPATPARQLDLLGGAGPGGGTPEGEGEDV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: DPH21_CANAL
Sequence: MTSETVIAPSLSTAQNDGTFTYDKVKSTAKERKHLNLKNPSDANEIKSKIWNYYSLSELIQYLGQKENDDFKYKRITLQFPDNLICDSATIVHELQRELNIVPQANQDTGESNTAQRVWILADTSYSACCVDEVAAEHVRSDLVVHFGDACLNEIDKLQAVFVLGKPTLDVDAIVKQIKTAYSTEQKVVLMSDAPHTYLLPEIAKQLPDYDILIADLPKTSRAKIIGYTPPPTGHKKFNRVFNTDTVEFGKYELFHITSPESPRLLQLTTNFASVTTYDPISGTVSTGPFPNLMRRYKYVHQARMAGTVGILVNTLSLANTKVLLNTIKEKIKEAGKKHYIFVVGKPNVAKLANFESVDIWCILGCDHQGIIIDQINEYYKPIVTPYELLLGLSDELSWTGKWVVDYKSVLEEYGNEVIQQNEDPDTDEDLPPVFDPVTGRYVSTSKPLRQINHLMVTSSEQGGVDDHDNQLVKRFSNAVAIKGTVSTSAIHLQNRHWTGLGSDYTEDENATGALVEDGRKGIARGYDI
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase, predominantly CBR1 (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2-1, Diphthamide biosynthesis protein 2-1.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUNI_AMBHE
Sequence: MGFLVASAVLVCVTSQRVPGYCKKKPAVGPCKALIEKWYFDYSTQSCKTFYYGGCGGNGNKFSSRKKCREACLPKRPSVPVCKQMPDPGFCRAYMPHWFFNSKSGYCEGFVYGGCQGNDNRFKSCWQCMKKCRTAREANRLCWKLTKEFNKKFLRNVPTAKPLPPK
What is the function of this protein?
Thrombin-specific inhibitor from tick hemolymph (Ki=20 nM).
What are the official names of this protein?
Amblin, Thrombin inhibitor.
What are the subcellular locations of this protein?
Secreted.
Protein: CHSY_MATIN
Sequence: MVMGATSLDEIRKAQRADGPAGILGIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFQRMCDKSMIRKRHMHLTEDFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAVRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAQDGVATTGEGLEWGVLFGFGPGLTVETVVLRSVPL
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase, Naringenin-chalcone synthase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: IRAP_ECOSE
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRVIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_VIBPA
Sequence: MKQYLDLCQRIVDQGVWVENERTGKRCLTVINADLTYDVANNQFPLVTTRKSFWKAAVAELLGYIRGYDNAEDFRKLGTKTWDANANLNDAWLNNPYRKGEDDMGRVYGVQGRAWAKPDGGHIDQLRKIVDDLTRGVDDRGEILNFYNPGEFHMGCLRPCMYSHHFSLLDDTLYLNSTQRSCDVPLGLNFNMVQVYVFLAIMAQITGKKPGQAFHKIVNAHIYEDQLELMRDVQLKREPLQAPTFHINPEIKSLEDLETWVTLDDFWVEGYEHHDPIRYPFSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCC2_ASHGO
Sequence: MSTFPGEDTRIPKRISEALSHQPLNHLVPKRELSRLLSKPVQISVQLESEDAFEEVPEELWQYPHPIDLDPLRLEESQPLRFRRPRGARLDYREDSSEIADLPGMGQLARACLSGTQLVDSAAIVESIESNAKKRKQTLAIGDVEMVSPDKKTKVMASVSPVSLNRVALGSQHLKTLERLMQYIGADESSAEFGDFEYWITLEDRATHILSEQCIDKLHIVFRNILSIPAVWTELDVSLLQRIMDVCVSTITICLEKIELKEYSHDYTLIAFGSSMVVFFIFLLDQNDRRLQLEQYMMVPLQFLTFTADNLEEEFDRGGNGVERSLAMLHSTLDVFYMYISNKPKLDDGLVVKLVYMFTELIMSTWSHNVSSVSLQNHIGNVKTIGMKSIEVLFEKLPEQRLFIIDELLSHLDNLPNTRSQKRMKNIGKNLHITHFSYIMLSILQVWNNYDYCSNLVSPDTEQLHDLIAHHAATQSDLEFAADHIIDTILKKCFSNISKYRFVFDQFVTDMTTVVTLPDWPVSDLILARLLKKLLSIFNPQSQKHINIESVALQGIGLIGSTILDIRLSSNSNPTANLIHLFNYPEDIDGLFKAYRTCLAYCTNSVQHHTPYKFLWCKQLDVLTKLKEMDKESQGWGSKLQQKFLSLIESIHLPLEQAANLGAVEILPTYCSTLLTSELINMYEPYLKLVLSLLERHKVKLRSGAIRCLALLISKDKNMLYTPIVKETIENRLTDSSPLVKDAILELIELGSSYIDFYQHININYNDDSMLVRKHVLRMNQIIYDDTEDIIIKAYVASRILRRIEDEEDVIIETARSELLKRWILSIQCPNAKPELQIKNCRVSIRVIAQLLVGGDKICDLFEHFLIFYVLNKNAHTEDQNKLISSSLCLLTDQVIEMVIENEAADVDNQREEEGRNIMKFLSVLSSCQDSFITKDHITALYPYLHSDTKSDFQLHILKVYRNTFEQLSHFKPKFLYDLETTILSRLPRMNVRELDEAIPLSWSLSRHRKDDTRICKACASCLGQLSPYIANATTDPSAVRPDGKLQRLLYLATGFARFCSFENTEGKFPNLKTRENIFEYVTKCLLMFTKENIHHVIRRIATKNLVKIASRYPKLFNSRHVLTVLDTQFEKGILDIQLVVLESLYDFFLAEERRSLIQVGVDGTISSNNELRKVVANHTKSDSINDGICSALVSRYLDKILKICLIADLNNAMVAIRFLKQILTYGYTNPSLCVPTVIALTASPNSYMRDLSSEMFSELLQGYESMAFNCLNQGIRLGTEYAVKIRPKQFHEDSMFLRRLQQLMSTNKRNRSKFLKVVKKTVFSNYLSTSVNYEESCYHIIYLLHNLSKISYDNMLELYEMLRSVISVSEYFSDRISERLDGFQSNQNTAAEVSAIIVTRLSIEEFKRFMFEQHHLSEAKLTLLDATDDENLRNKSVAALDDQVGSLHMENIFLGYENPINNKDYCWKYISTLHRDEI
What is the function of this protein?
Plays a structural role in chromatin.  Probably involved in sister chromatid cohesion, possibly by interacting with the cohesin complex (By similarity).
What are the official names of this protein?
Sister chromatid cohesion protein 2.
What is the protein family that this protein belongs to?
Belongs to the SCC2/Nipped-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YOHJ_ECOL6
Sequence: MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAVSTLVVFLVVSWSSQLVHGERKVVGQKGSEE
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHED_PARXL
Sequence: MSSALPIATNLYYDNHFQRPGVKLLPNEFYTTSEDMVLVTVLGSCVAACIQDRTAGIGGMNHFMLPDDGADVGQAASDSMRYGAYAMEVLINELIKAGGRRERFEAKVFGGGAVLAGMTTMNIGDRNSEFVRRYLALEKIRIVAEDLQGSHPRKVAFMPRTGQVMVKKLRLQQEAGVAEREQALMRQNAQARAERLAAARKRVELFSSPAASKARVELFSTPAAARPKVELFGAGSRPINSNNARTTEEA
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.