Protein: ITPR_PATPE
Sequence: MSEMSASFLHFGDIVSLYAEGSVNGFISTLGLVDDRCVVQPDFGDLNNPPKKFRDCLFKICPMNRYTAQKQFWKSAKPNVSSATDAVLLKKLQHAAEMEKKQNETENKKLMGSVIVYGNVIQLLHIKSHKYMTVNKRLPALLEKNAMRVTLDSSATEGSWFYIVPFYKLRSAGDNVVVGDKVVLNPVNAGQPLHPSNYELIDNPGCKEVNSVNCNTCWKVSLFMEHKENLDGLKGGDVVRLFHAEQEKFLTCDEYKKKSYIFLRTTGRVSATAATSSKALWETEVVQHDPCRGGAGHWNSLFRFKHLATGQYMAAEVDNDNTKDHTREKLRGPHGGTVYQMVPIIHGNDIASIFELDPTTLQGGDSMVPRSSYVRLRHLCTNTWVHSTSIPLDKGEDKPVMLKVGTAQIREDREAFAIIPVSPTEVRDLDFANDANKVLSAIASKLEKSSITQNERFVTQLLTDLVYFVSILPNNGGDALNVVVQNPDRDRQKLMREQDILKQIFKILKAPFTDNGDGAMLKMEELADPRHAPYRHICRLCYRILRLSQQAYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITATEIETFVNLVRKNGECRFLEYLSDLCVSNNQAIPVTQELICKSVLVERNSDILIETKLVRTQMEVEMEVEADDGTTEPVYTIEEEEEVVLFWKNGTKSKSIRSCHGGTENVKEDANVLKYYRYQLDLFSQMCLDRQYLAINQIGPQLDIDLIHRCMSDESLPYDLRASFTRLMLHMHVDRDPKEQVTPVKYAELWSEIPTQITIDDYDGANNLTHAGKEDAQPKFSLTIKFVEEYLCNVVSGVLVVYDKEQNKLTFEVVNLAKHLIYFGFYSFSELLRLTKTLLSILDCTALHGTAPGKLDPKADIGKGGVFRSIHGVGAVMTNMVLGKRLPTPVTRDPAWPLGWGLDNHNKQDELVMETKLKIIQILQFILNVRLDYRISCLLSIFKRDFDESKDSTDEITTSGKVWTASDFEHIEEQAEGIFGGSEENTPLDLDDDDGGRTFLRVLIHLTMHDYAPLVSGALQLLFKHFSQRQEVLEAFKQLQLLVSSQDVDNYKQIKQDLDQLRLVEKSELWVYKGQGPDEPMDGASGEQEHKKTEEGTSKPLKHESTSSYNYRVVKEILLRLSKLVCVEGNGTRKNRKHEQRLLRNMGAFTVVLELLQIPYEKNHDTRMNELMRLAHEFLQNFCWANPSNQVLLHKHIDLFLTPGLLEAQTMCHIFMNNFQLCSEVTEQVVQHFVHCIATHGRHVQYLKFLQAIVKADGQYIRKTQDMVMAELVNAGEDVLLFYNDKASFQMFINMMRTERERMDASSPSQYRHQPWTLLGLACTEGKNVYTEIKCHSLLPLDDIVRVATHEDCLPEVKNAYINFLNHCYVDTEVEMKEIYTSNHVWNLFENFLVDMAMVCNATHDRKHHDHMLEKTVTETVMNIITMFFSSPFADQSTTVQTRQPVFVRLLQGAFRVSQCDWLTGHQKYHVENCIKTLTDIAKNRGIAIPVDLDSQVNTLFSKSIVMKHTRHWLAINPNRSRDSMVAISRDYRSIIEGLQDIVSLLEDQLRPLVQAELSVLVDVLHRPELLFPFRHRARQKCESGAFISKLIKHTEKLLEEKEEKLCIKVLQTLKEMMTVDIDYSEKGEDLRQCLLLRYYGKSHLRMKHRGVVASGRGQTNVTSCGPGSRVLSRAEMTLAEVQCQLDKEGASSLVIDLVIKNSSNRVFLESVELGIALLEGGNTNIQKSIINCLMSDKNSEKFFKVFFDRMREASEIKATVTVNTGEGIGQTKPTEGRNGQHLRRRLTWPHEKGWTRPQRLNQRRAEDQLLADAALHTSKASRQSARVATTTLLASCQVLAGGAEKAKEEEKMSMEIAIMQPILRFLQLLCENHNRELQSYLRHQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINENNVALINQTLESLTEYCQGACHENQNAIANHESNGLDIITALILNDINPLGKNRMDLVLELKNNASKLLLAIMESRHDSENAERILLNMSPKQLVDVIKQAYQQEDLERDDDDELIIEEDDEAISPREVGHNIYILAHQLAHHNKELAALLKPTGPNSEYTDRALEYYFKHTAQIEIVRQDRTMEQIVFPVPQLCEYLTAETKIKVFTKAERDDQGSKVADFFEKTEDMFMEMKWQKKLRAQPILFLASSNMSKWSLVCFNLAVIVNLLVAFFYPFDVTTTELDHGLSMLVWLMAASLAAIVTLRRPSGIRPLVFATILRMLIFSIGVEPTLLFLAVLTIFNKCIFILSFLGNCGLLYKGVRGIFTDMEVLYHILYLIICFLGLFVHEFFYSLLLLDVVYQEDTLINVIHSVTRNWRSIAFTALLALILVYLFSIVGYLFLQDDFVYEVNPLRPAIATATATNKTGTSPPMPLPPESCPAGLEMEDCLKNNLSHVQAKEVSYDSGIEVGTERERACETLIMYIITTLNFGVRSGGGIGDVLRSPSTREPLYMARVIYDLLFFIVVIIIVLNLIFGVIIDTFADLRSEKQQKEEILKNTCFICGLNRSSFDNKSVSFEEHYKEEHSMWHYLYFIVLVKVKDPTEFTGPESYVYNMTKEKNQDWFPRMRAMSLDSDEGESEQNEMRILQNQLENTNSLVKVLSGQLRELKDQMTEQRKQKQRINLLSSPSIPQMGGP
What is the function of this protein?
Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium (By similarity).  Involved in the induction of intracellular calcium increase in eggs during fertilization and in the formation of the fertilization envelope during oocyte maturation.
What are the official names of this protein?
Inositol 1,4,5-trisphosphate receptor, ApIP3R.
What is the protein family that this protein belongs to?
Belongs to the InsP3 receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Multi- pass membrane protein. Note=In immature oocytes, distributed throughout the cytoplasm but not in the germinal vesicle (GV). During GV disintegration, expression is concentrated at the site where the GV was previously located. Following GV breakdown, expressed evenly throughout the egg cytoplasm.