PharMolix/UniProtQA huggingface dataset:
Protein: ISWI_DROME
Sequence: MSKTDTAAVEATEENSNETTSDAATSSSGEKEAEFDNKIEADRSRRFDFLLKQTEIFTHFMTNSAKSPTKPKGRPKKIKDKDKEKDVADHRHRKTEQEEDEELLAEDSATKEIFRFDASPAYIKSGEMRDYQIRGLNWMISLYENGINGILADEMGLGKTLQTISLLGYLKHFKNQAGPHIVIVPKSTLQNWVNEFKKWCPSLRAVCLIGDQDTRNTFIRDVLMPGEWDVCVTSYEMCIREKSVFKKFNWRYLVIDEAHRIKNEKSKLSEILREFKTANRLLITGTPLQNNLHELWALLNFLLPDVFNSSEDFDEWFNTNTCLGDDALITRLHAVLKPFLLRRLKAEVEKRLKPKKEMKIFVGLSKMQRDWYTKVLLKDIDVVNGAGKVEKMRLQNILMQLRKCTNHPYLFDGAEPGPPYTTDTHLVYNSGKMAILDKLLPKLQEQGSRVLIFSQMTRMLDILEDYCHWRNYNYCRLDGQTPHEDRNRQIQEFNMDNSAKFLFMLSTRAGGLGINLATADVVIIYDSDWNPQMDLQAMDRAHRIGQKKQVRVFRLITESTVEEKIVERAEVKLRLDKMVIQGGRLVDNRSNQLNKDEMLNIIRFGANQVFSSKETDITDEDIDVILERGEAKTAEQKAALDSLGESSLRTFTMDTNGEAGTSSVYQFEGEDWREKQKLNALGNWIEPPKRERKANYAVDAYFREALRVSEPKAPKAPRPPKQPIVQDFQFFPPRLFELLDQEIYYFRKTVGYKVPKNTELGSDATKVQREEQRKIDEAEPLTEEEIQEKENLLSQGFTAWTKRDFNQFIKANEKYGRDDIDNIAKDVEGKTPEEVIEYNAVFWERCTELQDIERIMGQIERGEGKIQRRLSIKKALDQKMSRYRAPFHQLRLQYGNNKGKNYTEIEDRFLVCMLHKLGFDKENVYEELRAAIRASPQFRFDWFIKSRTALELQRRCNTLITLIERENIELEEKERAEKKKKAPKGSVSAGSGSASSNTPAPAPQPKASQKRKSEVVATSSNSKKKKK
What is the function of this protein?
Energy-transducing component of the chromatin-remodeling complexes NURF (nucleosome-remodeling factor), ACF (ATP-utilizing chromatin assembly and remodeling factor), and CHRAC (chromatin accessibility complex) (PubMed:10856248, PubMed:11447119).  NURF catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin.  It is required for homeotic gene expression, proper larval blood cell development, normal male X chromosome morphology, ecdysteroid signaling and metamorphosis (PubMed:12502740, PubMed:16264191, PubMed:8521501, PubMed:8521502).
What are the official names of this protein?
Chromatin-remodeling complex ATPase chain Iswi, CHRAC 140 kDa subunit, Nucleosome-remodeling factor 140 kDa subunit, NURF-140, Protein imitation swi.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGA_PSESY
Sequence: MPEYVNWLRHASPYINAHRDCTFVVMLPGDGVAHPNFGNIVHDLVLLHSLGVRLVLVHGSRPQIESRLAQRGITPRYHRDLRITDTETLECVIDAVGQLRISIEARLSMDMAASPMQGSRLRVTSGNVVTARPIGVLEGVDYQHTGEVRRVDRKGINRLLDERHIVLLSPLGYSPTGEIFNLACEDVATRAAIDLAADKLLLFGAETGLLDEQGRLVRELRPQQVPAHLQRLGANYQAELLDAAAEACRGGVARSHIVSYAENGALLTELFTRDGGGTLVAQEQFELVREAAIEDVGGLMDLITPLEEQGILVRRSREVLEREITQFSVVEREGLIIACAALYPIADSESGELACLAVNPEYRHGGRGDELLERIENRARALGIKTLFVLTTRTAHWFRERGFEPSSVDRLPSARASLYNYQRNSKIFEKAI
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TF2B_SCHPO
Sequence: MNAPSFTGLPTSMLSVKMICSECREDPPNLVEEFSSGDTVCGSCGLVLGDRIIDTRSEWRTFSNSDEASGDPSRVGKVANPLLNGSQLDTTISSYDGAGAMLAKAQGRSVQVRGEKNLLTAYKEIGAMCDAISLPKVIADTAKQLYKRVDDHKALKGKSSQSIIAACIYIACRQGKVPRTFMEICTLTNVPKKEIGRVYKTLQRMLTEGGALHNSVDALKGHEYIQSSSTSAEDLMVRFCNRLMLPMSVQSAAAELARRAGLQGTLAGRSPISIAASGIYMISALMGYPKTPKEISEVTGVSDSTIRIAYKLLHAERKELIDPKWIANKAGNMDAMLPKP
What is the function of this protein?
General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II.
What are the official names of this protein?
Transcription initiation factor IIB, General transcription factor TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VP3_ORADR
Sequence: MTKQSIVIVLFAAIAMMACLQRVTAEPAPEPIAAPIAEPYANPEAIASPEAKDLHTVVSAILQALGKK
What is the function of this protein?
Exhibits strong antimicrobial activity against the fungi C. albicans and B. cinerea, and weaker activity against the Gram-negative bacterium E. coli and the Gram-positive bacterium S. aureus.
What are the official names of this protein?
Venom peptide 3, OdVP3.
What is the protein family that this protein belongs to?
Belongs to the MCD family.
What are the subcellular locations of this protein?
Secreted.
Protein: THS2_VITVI
Sequence: MASVEEIRNAQRAKGPATILAIGTATPDHCVYQSDYADYYFRVTKSEHMTALKKKFNRICDKSMIKKRYIHLTEEMLEEHPNIGAYMAPSLNIRQEIITAEVPKLGKEAALKALKEWGQPKSKITHLVFCTTSGVEMPGADYKLANLLGLEPSVRRVMLYHQGCYAGGTVLRTAKDLAENNAGARVLVVCSEITVVTFRGPSEDALDSLVGQALFGDGSAAVIVGSDPDISIERPLFQLVSAAQTFIPNSAGAIAGNLREVGLTFHLWPNVPTLISENIEKCLTQAFDPLGISDWNSLFWIAHPGGPAILDAVEAKLNLDKKKLEATRHVLSEYGNMSSACVLFILDEMRKKSLKGERATTGEGLDWGVLFGFGPGLTIETVVLHSIPMVTN
What is the function of this protein?
Mediates resistance to pathogens which are sensitive to stilbenes.
What are the official names of this protein?
Stilbene synthase 2, PSV21, Resveratrol synthase 2, Trihydroxystilbene synthase 2, StSy 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_NOSP7
Sequence: MSDKNEGYKVIADNRQARYLYEILETYEAGIELTGTEVKSIRAGKVNLQDGYALLRNGEAWLINIHISPYNASGQYFNHEPRRTRKLLLHRQELRKLIGKVEQQGLTLIPLKMYLKRGWVKVSIALGKGKKLHDKREDLKRRQDQRDIQRAMKSY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RL21_ENCCU
Sequence: MRSKGYRRGTRYLFSQDHRKHGVAHVSKYLEKYEIGDMVDILVNPAMMKGMPHKYYHGRTGRVYDVKPRSLNVALYKRVRGKYVIKKIIVRIEHVRKSRCSEESQKRILMAAEMARDAESRGVVLAPSKRKIEGPRKAVEVSLDNNQPIEVGYEPHVVIF
What are the official names of this protein?
60S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: FEN12_ORYSJ
Sequence: MGIKGLTKLLAEHAPGAAVRRRVEDYRGRVVAIDTSLSIYQFLIVVGRKGTEVLTNEAGEVTSHLQGMLNRTVRILEAGIKPVFVFDGEPPDMKKKELAKRSLKRDGSSEDLNRAIEVGDEDLIEKFSKRTVKVTKKHNEDCKRLLSLMGVPVVQAPGEAEAQCAALCENHKVFAIASEDMDSLTFGARRFLRHLTDLSFKRSPVTEFEVSKVLEELGLTMDQFIDLCILSGCDYCENIRGIGGQRALKLIRQHGYIEEVVQNLSQTRYSVPEDWPYQEVRALFKEPNVCTDIPDFLWTPPDEEGLINFLAAENNFSPDRVVKSVEKIKAANDKFSLGRGKLLAPVANLTGSTSTAGKEPKCILGGPGQVMKARSPLQVCKSSSLNFIHDNSKAFMLGRRSGFLRISTYASI
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA (By similarity).  May be required for cell proliferation.
What are the official names of this protein?
Flap endonuclease 1-B, FEN-1-B, Flap structure-specific endonuclease 1-B, OsFEN-1b.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: ATPD_RHOPB
Sequence: MAAENPSVSGVSGRYATALFELARDEKAVDAVKADLDRFKAMLADSPELTRLVRSPVFSAETQSKALAAVLDKAGFAGTTAKFLKVLTANRRLFTVTDVIRAYGALVAKFKGEATADVTVAEPLSEKNLDALKTALKSVTGKDVALNVNVDPAIIGGLVVKLGSRMVDSSLRTKLNSIKHAMKEAG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACPS_RHOPS
Sequence: MIIGIGSDLIDITRIAKVIERHGERFLDRIFTETERARAGRRDKQPNLVAATYAKRFAAKEACSKALGTGIRQGVWWRDMGVVNLPGGRPTMALTGGAKARLDALTPAGMIAQIDLSITDEWPLAQAFVVISAIPATAS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPVI_MOUSE
Sequence: MSPASPTFFCIGLCVLQVIQTQSGPLPKPSLQAQPSSLVPLGQSVILRCQGPPDVDLYRLEKLKPEKYEDQDFLFIPTMERSNAGRYRCSYQNGSHWSLPSDQLELIATGVYAKPSLSAHPSSAVPQGRDVTLKCQSPYSFDEFVLYKEGDTGSYKRPEKWYRANFPIITVTAAHSGTYRCYSFSSSSPYLWSAPSDPLVLVVTGLSATPSQVPTEESFPVTESSRRPSILPTNKISTTEKPMNITASPEGLSPPFGFAHQHYAKGNLVRICLGATIIIILLGLLAEDWHSRKKCLQHRMRALQRPLPPLPLA
What is the function of this protein?
Collagen receptor involved in collagen-induced platelet adhesion and activation (PubMed:16139873, PubMed:24368846).  Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation.  This procoagulant function may contribute to arterial and venous thrombus formation.  The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2.
What are the official names of this protein?
Platelet glycoprotein VI, GPVI, Glycoprotein 5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: C1QR1_MOUSE
Sequence: MAISTGLFLLLGLLGQPWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQQALTQLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYKASKSSCIFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLALGGPGRVTYTTPFQATTSSLEAVPFASVANVACGDEAKSETHYFLCNEKTPGIFHWGSSGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPCTGGGMCHSVPLSENYTCRCPSGYQLDSSQVHCVDIDECQDSPCAQDCVNTLGSFHCECWVGYQPSGPKEEACEDVDECAAANSPCAQGCINTDGSFYCSCKEGYIVSGEDSTQCEDIDECSDARGNPCDSLCFNTDGSFRCGCPPGWELAPNGVFCSRGTVFSELPARPPQKEDNDDRKESTMPPTEMPSSPSGSKDVSNRAQTTGLFVQSDIPTASVPLEIEIPSEVSDVWFELGTYLPTTSGHSKPTHEDSVSAHSDTDGQNLLLFYILGTVVAISLLLVLALGILIYHKRRAKKEEIKEKKPQNAADSYSWVPERAESQAPENQYSPTPGTDC
What is the function of this protein?
Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA).  May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens.  May play a role in intercellular adhesion.  Marker for early multipotent hematopoietic precursor cells.  May play a role in cell-cell interactions during hematopoietic and vascular development.
What are the official names of this protein?
Complement component C1q receptor, C1q/MBL/SPA receptor, C1qR(p), C1qRp, Cell surface antigen AA4, Complement component 1 q subcomponent receptor 1, Lymphocyte antigen 68, Ly-68.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CH10_RHIWR
Sequence: MSFRPLHDRVLVRRVEAEEKTAGGIIIPDSAKEKPQEGEVVAVGGGSKAEDGKVTPLDVKAGDKILFGKWSGTEVKINGEDLLIMKESDILGIVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1286_LEGPH
Sequence: MAGHSKWANIKFRKGVQDAKRGKIFTKLIREITVAARMGGGDESSNPRLRDAVKKALNANMKRDTIDNAVKRGVGGVDGEAMIAMRYEGYGPGGVAILVDCLSDNKNRTVSEVRHAFSKHGGNLGTDGSVSYLFTNQGEILMASNQPEDKVMEIAIDAGASDVAVEDGQIEIITPVEAYHTVLNALQDAGLEVEQSHLTMRAQTLVPINDETAESLIKLIDMLEDLDDVQEVYSNAEFSEKILESMN
What are the official names of this protein?
Probable transcriptional regulatory protein lpg1286.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXKG_KLULA
Sequence: MSDPKLTKAVDSICDQFIVTKSKISQLTEYFIDCMEKGLEPCESDISQNKGLPMIPTFVTDKPSGQEHGVTMLAADLGGTNFRVCSVELLGNHEFKIEQEKSKIPTFFFQDDHHVTSKDLFQHMALITHQFLTKHHKDVIQDYKWKMGFTFSYPVDQTSLSSGKLIRWTKGFKIGDTVGQDVVQLFQQELNDIGLSNVHVVALTNDTTGTLLARCYASSDAARAINEPVIGCIFGTGTNGCYMEKLENIHKLDPASREELLSQGKTHMCINTEWGSFDNELNHLPTTSYDIKIDQQFSTNPGFHLFEKRVSGLYLGEILRNILLDLEKQELFDLKESVLKNNPFILTTETLSHIEIDTVENDLQDTRDALLKAADLETTFEERVLIQKLVRAISRRAAFLAAVPIAAILIKTNALNQSYHCQVEVGCDGSVVEHYPGFRSMMRHALALSPIGPEGERDVHLRISKDGSGVGAALCALHANY
What is the function of this protein?
Glukokinase specific for aldohexoses.  Phosphorylates glucose and mannose, but not fructose.
What are the official names of this protein?
Glucokinase-1, Glucose kinase 1, GLK-1, Hexokinase GLK1.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
Protein: KGUA_CUTAK
Sequence: MSSVPVIPQARGLRHTGPVTVAVVSGPTAVGKGTVVGALLRSHPEIVVSRSVTTRPPRPTERDGIDYDFITPEQFDKLVDGEGLLEWATVHNSHRYGTPRGPVERAVADNRTVVLEIDLQGARQVRETYPQATQIFLAPPSWEELVHRLIGRGTETPEQQKQRLETAKVELANADEFDAVVVNDTVDHAVAHLVELLSL
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_COXBR
Sequence: MKLILQEKVANLGNIGDQVVVKPGYARNFLLPLGKAVPATPEHIAEFEKQRAELEKAAAELLAKAKARAKKLEDKSFKITANASDEGRLFGSIGPREIAQAITEAGIEIEKREVDLSQGPIRQVGEYEVPLRLHTDVSVNVKIEVAPENSNS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GWD1_ARATH
Sequence: MSNSVVHNLLNRGLIRPLNFEHQNKLNSSVYQTSTANPALGKIGRSKLYGKGLKQAGRSLVTETGGRPLSFVPRAVLAMDPQAAEKFSLDGNIDLLVEVTSTTVREVNIQIAYTSDTLFLHWGAILDNKENWVLPSRSPDRTQNFKNSALRTPFVKSGGNSHLKLEIDDPAIHAIEFLIFDESRNKWYKNNGQNFHINLPTERNVKQNVSVPEDLVQIQAYLRWERKGKQMYNPEKEKEEYEAARTELREEMMRGASVEDLRAKLLKKDNSNESPKSNGTSSSGREEKKKVSKQPERKKNYNTDKIQRKGRDLTKLIYKHVADFVEPESKSSSEPRSLTTLEIYAKAKEEQETTPVFSKKTFKLEGSAILVFVTKLSGKTKIHVATDFKEPVTLHWALSQKGGEWLDPPSDILPPNSLPVRGAVDTKLTITSTDLPSPVQTFELEIEGDSYKGMPFVLNAGERWIKNNDSDFYVDFAKEEKHVQKDYGDGKGTAKHLLDKIADLESEAQKSFMHRFNIAADLVDEAKSAGQLGFAGILVWMRFMATRQLVWNKNYNVKPREISKAQDRLTDLLQDVYASYPEYRELLRMIMSTVGRGGEGDVGQRIRDEILVIQRKNDCKGGIMEEWHQKLHNNTSPDDVVICQALMDYIKSDFDLSVYWKTLNDNGITKERLLSYDRAIHSEPNFRGEQKDGLLRDLGHYMRTLKAVHSGADLESAIQNCMGYQDDGEGFMVGVQINPVSGLPSGYPDLLRFVLEHVEEKNVEPLLEGLLEARQELRPLLLKSHDRLKDLLFLDLALDSTVRTAIERGYEQLNDAGPEKIMYFISLVLENLALSSDDNEDLIYCLKGWQFALDMCKSKKDHWALYAKSVLDRSRLALASKAERYLEILQPSAEYLGSCLGVDQSAVSIFTEEIIRAGSAAALSSLVNRLDPVLRKTANLGSWQVISPVEVVGYVIVVDELLTVQNKTYDRPTIIVANRVRGEEEIPDGAVAVLTPDMPDVLSHVSVRARNGKICFATCFDSGILSDLQGKDGKLLSLQPTSADVVYKEVNDSELSSPSSDNLEDAPPSISLVKKQFAGRYAISSEEFTSDLVGAKSRNIGYLKGKVPSWVGIPTSVALPFGVFEKVISEKANQAVNDKLLVLKKTLDEGDQGALKEIRQTLLGLVAPPELVEELKSTMKSSDMPWPGDEGEQRWEQAWAAIKKVWASKWNERAYFSTRKVKLDHDYLCMAVLVQEVINADYAFVIHTTNPSSGDSSEIYAEVVKGLGETLVGAYPGRSLSFICKKNNLDSPLVLGYPSKPIGLFIRRSIIFRSDSNGEDLEGYAGAGLYDSVPMDEEDQVVLDYTTDPLITDLSFQKKVLSDIARAGDAIEKLYGTAQDIEGVIRDGKLYVVQTRPQV
What is the function of this protein?
Mediates the incorporation of phosphate into starch-like alpha-glucan, mostly at the C-6 position of glucose units.  Acts as an overall regulator of starch mobilization.  Required for starch degradation, suggesting that the phosphate content of starch regulates its degradability.
What are the official names of this protein?
Alpha-glucan water dikinase 1, chloroplastic, Protein starch excess 1, Protein starch-related R1.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Note=Starch granules.
Protein: FAAA_CAEEL
Sequence: MKSFVSVPQNSDFPIQNLPYGVFSTKADSSRHIGVAIGDQILNLAEIANLFDGPQLKAHQDVFKQSTLNAFMALPRPAWLEARARIQQLLSEDCAVLRDNAHLRSRALVAQSDATMHLPAQIGDYTDFYSSIHHATNVGIMFRGKENALMPNWKWLPVGYHGRASSIVVSGTDLKRPVGQTKAPDAEVPSFGPSKLMDFELEMAFFVGGPENELGTRVPIEKAEDRIFGVVLMNDWSARDIQAWEYVPLGPFLAKSFATTVSPWVVSIEALRPYFVENPVQDPVPPAYLHHDDPFTLDINLAVSIRPEGDAVDHIVCKTNFKHLYWTLKQQLAHHTVNGCNLRAGDLLGSGTVSGPEEGAYGSMLELSWRGAKEVPVGSEIRKFLKDGDEVNLSGVCEKNGVRIGFGECRGKVLPADI
What is the function of this protein?
Fumarylacetoacetase involved in the tyrosine degradation pathway.
What are the official names of this protein?
Fumarylacetoacetase, FAA, Beta-diketonase, Fumarylacetoacetate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: WZYE_ECOLU
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVILMGVALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNTANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPG_ACICJ
Sequence: MASLKALRNRIASVKSTQKITKAMKMVAAAKLRRAQAQAEAARPYATRMAAMMGALAEGAAENPNAPALLVGNGADRTHLIVVVSADRGLAGPFNASINRAARARARKLEAEGKQVRLFTVGRKGRDFFRRDMREKIIGEANFVGKKTIEFADAEAIANQIIAAFNDGKFDVCTLMFNRFVSVMSQVPSETPLIPASAGQAANDNAGSDQPAGDYEIEPDDGTLLDRLLPRNLAVQIYSALLESAAGEQGARMTAMDNATRNAGEMINRLTLNYNRTRQANITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: AROQ_BUCAT
Sequence: MKNNINILLINGPNLNLLGTRETEIYGDITLPDLLKNLEKRAKKLNMSLKHIQSNAEHVLIDKIHSSRKNINYIIINPAAFTHTSIAIRDALIAVEIPFIEIHISNIYSREDFRSHSWLSDISQGVICGLGLDGYHWALETISNRLIHLK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RL31_YERPG
Sequence: MKQGIHPKYEQVTASCSCGNVIKINSTVGHDLNLDVCGECHPFYTGKQRDVASGGRVDRFNKRFSVPGAKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: HST1_YEAST
Sequence: MNILLMQRIVSFILVVSQGRYFHVGELTMTMLKRPQEEESDNNATKKLKTRLTYPCILGKDKVTGKFIFPAITKDDVMNARLFLKDNDLKTFLEYFLPVEVNSIYIYFMIKLLGFDVKDKELFMALNSNITSNKERSSAELSSIHAKAEDEDELTDPLEKKHAVKLIKDLQKAINKVLSTRLRLPNFNTIDHFTATLRNAKKILVLTGAGVSTSLGIPDFRSSEGFYSKIRHLGLEDPQDVFNLDIFLQDPSVFYNIAHMVLPPENMYSPLHSFIKMLQDKGKLLRNYTQNIDNLESYAGIDPDKLVQCHGSFATASCVTCHWQIPGEKIFENIRNLELPLCPYCYQKRKQYFPMSNGNNTVQTNINFNSPILKSYGVLKPDMTFFGEALPSRFHKTIRKDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQILINRDMVTHAEFDLNLLGFCDDVASLVAKKCHWDIPHKKWQDLKKIDYNCTEIDKGTYKIKKQPRKKQQ
What is the function of this protein?
NAD-dependent histone deacetylase involved in telomeric silencing.  Histone deacetylase proteins act via the formation of large multiprotein complexes that are responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Restores silencing at HMR in SIR2 mutants when overexpressed.  Required to repress middle sporulation genes during vegetative growth.  Acts as a sensor of NAD(+) levels and regulator of NAD(+) biosynthesis.  Regulates the gene expression of de novo NAD(+) biosynthesis genes.
What are the official names of this protein?
NAD-dependent protein deacetylase HST1, Homologous to SIR2 protein 1, Regulatory protein SIR2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class I subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=But not nucleolar, and cytoplasmic.
Protein: ATG8_ASHGO
Sequence: MSSFKSEYPFEKRKAESERICSQFENRVPVICERAEKSDIPEVDRRKYLVPADLTVGQFVYVIRRRIKLPAEKAIFIFVNDTLPPTAALMFAVYQEHKDKDGFLYVKYSGENTFGSEENQ
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.