PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_STRP8
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKLQEYGHGSFVAKMGAEAIQDLLKRVDLAAEIAELKEELKSASGQKRIKAVRRLDVLDAFNKSGNKPEWMVLNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVAKEYAGNVKAAKRMVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDAGREGEGMIFKDKDEAVMAYRNGYAHLHSRVGIAVDSMPNKPWKDSQRHKIMVTTVGKILFNDIMPEDLPYLQEPNNANLTEGTPDKYFLEPGQDIQEVIDGLEINVPFKKKNLGNIIAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIDAAHHRVEEINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLICAITDGKEVTETLEERLQGRYTRKSVKHPETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGNVVEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEGSIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDISDFTDANKDIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNIEPQAMNEIEVIDHTEVSAEAVFTAEAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: GHRB_SALSV
Sequence: MKPSIILYKTLPDDLLHRLEAHFTVTQVPNLHPETVARHAQAFSSAQGLLGASETVNRALLEKMSALRAASTISVGYDNVEVDALTARKIVLMHTPAVLTETVADTVMALMLATARRVVDVAERVKAGEWTESIGPAWFGVDVHHKTLGIVGMGRIGMALAQRAHFGFTMPVLYHARRRHQEAEDRFNARYCDLDTLLQEADFVCVILPLTAETRHLFGATQFARMKSSAIFINAGRGPVVDENALIAALQNGEIYAAGLDVFEQEPLSVDSPLLNMSNVVAVPHIGSATHETRYNMMACAVDNLIDALQGKIEKNCVNPQAAG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHB_MYCA1
Sequence: MAETPRLLFVHAHPDDESLGTGATIAHYTAAGADVRVVTCTLGEEGEVIGERWAELAVDRADQLGGYRIGELTAALRELGVGEPCYLGGAGRWRDSGMPGTPKRRRQRFIDADEREAVGALVAVIREQRPHVVVGYDPAGGYGHPDHVHVHTVTTAAVAAAGAGDFPGEPWAVPKFYWSVFATRPFEAAVQALTPEDLRPDWSMPSAEQFTFGYADDHIDAVVAAGPHAWAAKRAALAAHATQVVVGPTGRACALSNNVALPILDEEHYVLVAGAAGARDERGWETDLLAGLEFGAAPRR
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, GlcNAc-Ins deacetylase, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.
Protein: CYO2_AFREN
Sequence: GIPCGESCVWIPCISSAIGCSCKSKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism (By similarity).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (PubMed:32414842).
What are the official names of this protein?
Cycloviolacin-O2, Cyclotide hyen-O2.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: TL18_SPIOL
Sequence: DLNKFEAEMRGEFGIXSA
What are the official names of this protein?
Thylakoid lumenal 18.3 kDa protein, P18.3.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: EAF6_DEBHA
Sequence: MTDKEGQEVKDAPSIEQYTALKDQLTQQILKKQELDSKLSKLEDSIYEKENEYFNESVYGNIVKGFQNFTKTNTGGLNKRRITYTDDDHIFSLSSVNYIKTIMKRQGVNSNGGRNEDLDDYEDSIDPNNGNAGGNTPNTTGTNNQSASQANSNSNQSTPGRKRKIRTIDD
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
Chromatin modification-related protein EAF6.
What is the protein family that this protein belongs to?
Belongs to the EAF6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PQQB_AZOVD
Sequence: MHIRILGSAAGGGFPQWNCNCRNCHGLRQGTLRATPRSQSSIALSDDGANWILCNASPDIRAQIEAFPALQPARAVRDTAIRALILLDSQIDHCTGLLGLREGCPHEVWCTEMVHQDLTTGFPLFAMLEHWNGGLHWKPIVLERSFAVDACPALRFTPIPLRSAAPPYSPHRHDPHPGDNLGLLVEDSRTGGTLFYAPGLGRVDAPLRERMRRADCLLVDGTLWRDDEMIHAGCGSKLGSEMGHLPQSGAGGMLEVLDGLDGRKVLIHINNTNPILDEDSPERAQLVARGIEVARDGMDIDL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: IL2_HUMAN
Sequence: MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
What is the function of this protein?
Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance (PubMed:6438535).  Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG) (PubMed:16293754, PubMed:16477002).  Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3 (PubMed:7973659).  In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5 (PubMed:8580378).  This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways (PubMed:25142963).  Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well (PubMed:6608729).  Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production (PubMed:6438535).  Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance.  Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
What are the official names of this protein?
Interleukin-2, IL-2, T-cell growth factor, TCGF.
What is the protein family that this protein belongs to?
Belongs to the IL-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEPF_LIMF3
Sequence: MASKFFSNLFGVVDDEPETADYYEDQQPAQQAPAPVPTPAPTRSNKVVSINNARVAPQPNSSSKIELVEPRVYGDGKEIVNHLLNGNAVIVNFDQMDAKVAFRIVEYMKGATYAISGKIERIDAEIFLCTPQNFEISGKLAPTLSSDGLDDRGDRY
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: MT2_ACTDE
Sequence: MSCCGGKCGCGSSCSCGSGCGGCGMYPDLSYSEMTTTETLIVGVAPQKTYFEGSEMGVAAENGCKCGSDCKCDPCTCK
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein type 2.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: RSMH_BIFAS
Sequence: MTDFSQIHKPVLLQECVDLVTPALHASDSVAVDCTLGLAGHTIAFLKAAPNATVIGIDRDEEALDKATARIAQEGLSARFVPVHAAFDQFDEVLRAQGVSRVQAVFMDLGLSSLQIDERERGFSYAHDAPLDMRMDTSQALTAREILATYDADRLAHIFKEYGEERFSKPIAKRIVQQRQSSPLETSSQLTALVDAVIPAARRGSGNPAKRVFQALRIEVNGELDKLRRTLPQIGLHLAVGGRLVVESYHSLEDRTVKNFMAQGLRVDAPADMPVIPPDMQPFFKALTKGAVKADAGEIAYNPRSASVRLRAVELTRPLPQRWVHAFELESQGSEDGVRGAHGHRRRTQARRG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_STRP3
Sequence: MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKTGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CY1_RHOCB
Sequence: MKKLLISAVSALVLGSGAAFANSNVPDHAFSFEGIFGKYDQAQLRRGFQVYNEVCSACHGMKFVPIRTLADDGGPQLDPTFVREYAAGLDTIIDKDSGEERDRKETDMFPTRVGDGMGPDLSVMAKARAGFSGPAGSGMNQLFKGMGGPEYIYNYVIGFEENPECAPEGIDGYYYNKTFQIGGVPDTCKDAAGVKITHGSWARMPPPLVDDQVTYEDGTPATVDQMAQDVSAFLMWAAEPKLVARKQMGLVAMVMLGLLSVMLYLTNKRLWAPYKGHKA
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.  c1 functions as an electron donor to cytochrome c.
What are the official names of this protein?
Cytochrome c1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CDC26_YEAST
Sequence: MIRRAPTTLQLSHDDVTSLIDDLNEQKLKQQLNIEKTKYFQGKNGGSLHSNTDFQDTSQNIEDNNNDNDNDIDEDDDMSSYNDKAASVAHTRVLNSLHLSTDSNTAHETSNANDNHNPFYIREE
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome.  In early mitosis, the APC/C is activated by CDC20 and targets securin PDS1, the B-type cyclin CLB5, and other anaphase inhibitory proteins for proteolysis, thereby triggering the separation of sister chromatids at the metaphase-to-anaphase transition.  In late mitosis and in G1, degradation of CLB5 allows activation of the APC/C by CDH1, which is needed to destroy CDC20 and the B-type cyclin CLB2 to allow exit from mitosis and creating the low CDK state necessary for cytokinesis and for reforming prereplicative complexes in G1 prior to another round of replication.
What are the official names of this protein?
Anaphase-promoting complex subunit CDC26, Cell division control protein 26.
What is the protein family that this protein belongs to?
Belongs to the CDC26 family.
Protein: ATP4B_RAT
Sequence: MAALQEKKSCSQRMAEFRQYCWNPDTGQMLGRTPARWVWISLYYAAFYVVMTGLFALCIYVLMQTIDPYTPDYQDQLKSPGVTLRPDVYGERGLQISYNISENSSWAGLTHTLHSFLAGYTPASQQDSINCSSEKYFFQETFSAPNHTKFSCKFTADMLQNCSGLVDPSFGFEEGKPCFIIKMNRIVKFLPSNNTAPRVDCTFQDDPQKPRKDIEPLQVQYYPPNGTFSLHYFPYYGKKAQPHYSNPLVAAKFLNVPKNTQVLIVCKIMADHVTFDNPHDPYEGKVEFKLTIQK
What is the function of this protein?
The beta subunit of the gastric H(+)/K(+) ATPase pump which transports H(+) ions in exchange for K(+) ions across the apical membrane of parietal cells.  Plays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (By similarity).  Within a transport cycle, the transfer of a H(+) ion across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation of the alpha subunit that shifts the pump conformation from inward-facing (E1) to outward-facing state (E2).  Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle (By similarity).
What are the official names of this protein?
Potassium-transporting ATPase subunit beta, Gastric H(+)/K(+) ATPase subunit beta, Proton pump beta chain.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type II membrane protein. Cell membrane; Single- pass type II membrane protein. Note=Localized in the apical canalicular membrane of parietal cells.
Protein: PSBT_ARATH
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKISTKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATPB_AQUAE
Sequence: MAEVIKGKVVQVIGPVVDVEFEGVKELPKIKDGLKTIRRAIDDRGNWFEEVLFMEVAQHIGEHRVRAIAMGPTDGLVRGQEVEYLGGPIKIPVGKEVLGRIFNVAGQPIDEQGPVEAKEYWPMFRNPPELVEQSTKVEILETGIKVIDLLQPIIKGGKVGLFGGAGVGKTVLMQELIHNIARFHEGYSVVVGVGERTREGNDLWLEMKESGVLPYTVMVYGQMNEPPGVRFRVAHTGLTMAEYFRDVEGQDVLIFIDNIFRFVQAGAEVSTLLGRLPSAVGYQPTLNTDVGEVQERITSTKKGSITAIQAVYVPADDITDPAPWSIFAHLDATTVLTRRLAELGIYPAIDPLESTSKYLAPEYVGEEHYEVAMEVKRILQRYKELQEIIAILGMEELSDEDKAIVNRARRIQKFLSQPFHVAEQFTGMPGKYVKLEDTIRSFKEVLTGKYDHLPENAFYMVGTIEDVIEKAKQMGAKV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYP_SPHEL
Sequence: MIKHALSVTRDGDFAQWYQTVISEADMAEDSGVRGCMVIRPWGYGIWERIQRLLDDRIKATGHENCYFPLFIPLSYFEKEAEHVDGFAKEMAVVTHHRLIQKDGRLVPDPEAKLEEPLVVRPTSETVIGAAMSRWVQSWRDLPVLINQWANVVRWEMRTRMFLRTAEFLWQEGHTAHATVEEAQEETRKMLEVYRDFAETCLAMPVVAGEKPENERFPGAVSTFSIEAMMQDGKALQAGTSHFLGTTFSSAQDIKFQNSEGQFELAQTTSWGVSTRMIGGLIMVHGDDDGLRVPPMVAPWQIVIVPMLRDQPEDAATIDYCKSLQAELAKLTALGEPVRALLDLKAVKAQTKRWGWVKKGAPIVIEVGGRDVAGGNVSVIQRNKLYREDGKLDSRIMPRGDFVAEAAAILESIQQGLYLDARERLDSNIRRDVTDFDGLAAMFADSVKFPGWAEVSWAKPTGAELDAVVERLKALKLTFRNVPGTAAPAEGTCLFTGKPAVERILVARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKOA_BACSU
Sequence: MRLLTLTEYCLLIFFTGFYLAVTGFTAKDIGLYIGIALIYIFSHIFSKRLLEKRGKENKQVHLFFSVLAIIGSVFITVLCIALVASFSK
What are the official names of this protein?
Uncharacterized protein YkoA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RISB_CHLL2
Sequence: MQIKQIEGSLSAKDIRFALVVSRFNDFIGQKLVEGAIDCILRHGGSEEQITVYRCPGAFELPMVAKKVAMSGSADAVIALGVIIRGSTPHFDVIAAEATKGIAQVSLDTMIPVSFGVLTTENLEQAIERAGTKAGNKGFDAAMTAMEMVNLYRQF
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: 5HTR_LYMST
Sequence: MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSLTVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLVMPLSVVSEISKVWFLHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTSIDYIRRRSARRILLMIMVVWIVALFISIPPLFGWRDPNNDPDKTGTCIISQDKGYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSSSSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYSRTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPFVDPEGIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYRRGHR
What is the function of this protein?
This is a receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that function as a neurotransmitter, a hormone, and a mitogen.
What are the official names of this protein?
5-hydroxytryptamine receptor, 5-HT receptor, Serotonin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CEC_CALVI
Sequence: GWLKKIGKKIGRVGQHTRDATIQGLAVAQQAANVAATAR
What is the function of this protein?
Antibacterial peptide active against Gram-negative bacterium E. coli (Ref. 1, PubMed:26177023).  Has no activity against Gram-positive bacterium M. luteus (Ref. 1).  Weakly active against M. luteus (PubMed:26177023).
What are the official names of this protein?
Cecropin.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CXL16_BOVIN
Sequence: MMLGRTSRLLLVLLFIAYATTSGNGNEGSKVGSCPCDHTVSSHSPPNENIMRHLRKYLKAYQRCFSYVRFQLPLKNVCGGSTDGWVQELMHCFDSGECGHAQPRVVDAPLHRTQLPEPTEAAPSDTATTSQTYLPSTLQRTQQPTPLEGALSLDSKLIPTHETTTYTSGHSLGAEPEAKENQKQLKENRGPQAGTSATVPVLSLLAIVFILAGVLLYVVCKRRKNQLLQHPPDLAASLYTCSRRTRAENGTL
What is the function of this protein?
Induces a strong chemotactic response.  Induces calcium mobilization.  Binds to CXCR6/Bonzo.  Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity).
What are the official names of this protein?
C-X-C motif chemokine 16, Transmembrane chemokine CXCL16.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SPB10_PAPAN
Sequence: MDTLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLAMVYLGTKGTTAAQMGQVLQFNRDQGVKSSPESEKKRKMEFNSSNSEEIHSDFHTLISEILKPNDDYLLKTANAIYGEKTYPFHNKYLEDMKTYFGAEPQSVNFVEASDQIRKEINSWVERQTEGKIQNLLPDDSVDSTTRMILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLQIFHIEKPQAVGLQLYYKSRDLSLLILLPEDINGLVQLEKDITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGTGSEIESRIRVPSIEFNANHPFLFFIRHNKTNSILFYGRLCSP
What is the function of this protein?
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF.  May regulate protease activities in the cytoplasm and in the nucleus (By similarity).
What are the official names of this protein?
Serpin B10.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GRPE_OENOB
Sequence: MVEKKKSQAEKNNQSATEEEIEKAVKGSKRDSNAADEKNSASAAASSSAVSDAEPAVDYEDKFYRAEAEMQNMQQRFNKERASILKYEGQDLAKSILPALDNLERALSVSAGDPASKKIQDGVELTYKSLSNALTDNGIVKIGRAGDQFDPNLHNAIQKTPIDDPEKQKEGTIAVVLQKGYQLHDRVLRPAMVSVYTK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BROX_CAEEL
Sequence: MSHWFHRNPIKPTEFVKFDLKGVLTTDTCSKICGELRLRRDKLVSQFKNASNDLEEVTKEFNEYLRLFAGFLIEIQSSMVELENKDAGNKNSKLIPLIRFKWGNSMLPQAATEVSDTWFEALSMIQCMAMWLTKHAASMAGKDEVRESDAKECLQCLRQAGGMFQYVKDESSRLSGANEVEGSDFDPKVMETYILTATAEAQEVIVARAIEMKHDDGLISSLAAVTASIFSKADQCLNNLPDESFARWRRYLQLKHHFYLAYAFAFLGQKQLSEDKCGEAVRACKQGIAEYGVAKEMAAMYATATGPGTRIKPEQHLFFRRIEPLLNRHLEKAERENGFIYHQKVPDEIPQLDVEATYGLAKLDSFTYPPPAESWNTAVYSAFDLSKANMPDFSKIKKSKSKLDPVHEEKIYQTEKDPSNSSGCVIA
What are the official names of this protein?
BRO1 domain-containing protein BROX homolog.
What is the protein family that this protein belongs to?
Belongs to the BROX family.
Protein: RS4_ACIC5
Sequence: MARYTGPVCRLCRREGMKLFLKGTKCFTDKCAIEKRNFAPGQHGRDRKAKIVGYGLQLREKQKAKRIYFTLEGQFREYYEKASRAPGVTGELLIQQLECRLDNIAFRLGFATSRRQARQIVRHGHVEVNGRKVNIPSFQVKVGDEIKIRPNSSKLVVVEMGRDFASGQPAPAWLQVDHANLSGKVVSLPKREDVNLPVNEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DADA_CROS8
Sequence: MHVVVLGSGVVGVASAWYLRQAGHEVTVIDREPGPALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAISLDGTHFQLKWMWQMLRNCDTRHYMQNKGRMVRLAEYSRDCLKALRESTGIQYEGRQGGTLQLFRTEQQYENASRDIAVLESEGVPFRLLKAAELAQVEPALADVAHKLTGGLQLPNDETGDCQLFTTRLAQMAEAAGVVFRYNTPVDRLLSEGQRIYGVKCGDEVIKADGYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIADESGAPVSTVLDETYKIAITRFDNRIRVGGMAEIVGFNTELLKPRQETLEMVVRDLYPRGGHIEQAKFWTGLRPMTPDGTPVVGRTEFKNLWLNTGHGTLGWTMACGSGQLLSDIISGRTPAIPFEDLSVARYAPGFTPSSSHRLHGAHP
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: RL33_POLNA
Sequence: MAKGGREKIKLQSTAGTGHFYTTDKNKKTTPEKMLIMKFDPKARKHVEYKEIKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.