PharMolix/UniProtQA huggingface dataset:
Protein: FETP_HERAR
Sequence: MTRMVHCIKLDKEAEALDFPPYPGELGKRIYESVSKEAWAAWLKHQTMLVNENRLNLADVRARKYLATQMEKHFFGEGADAAQGYVPPTE
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: UC23_MAIZE
Sequence: AGDKPGDALLDEWLG
What are the official names of this protein?
Unknown protein from spot 502 of 2D-PAGE of etiolated coleoptile.
Protein: AGL82_ARATH
Sequence: MVPKVVDLQRIANDKTRITTYKKRKASLYKKAQEFSTLCGVETCLIVYGPTKATDVVISEPEIWPKDETKVRAIIRKYKDTVSTSCRKETNVETFVNDVGKGNEVVTKKRVKRENKYSSWEEKLDKCSREQLHGIFCAVDSKLNEAVTRQERSMFRVNHQAMDTPFPQNLMDQQFMPQYFHEQPQFQGFPNNFNNMGFSLISPHDGQIQMDPNLMEKWTDLALTQSLMMSKGNDGTQFMQRQEQPYYNREQVVSRSAGFNVNPFMGYQVPFNIPNWRLSGNQVENWELSGKKTI
What is the function of this protein?
Probable transcription factor that may function in the maintenance of the proper function of the central cell in pollen tube attraction.
What are the official names of this protein?
Agamous-like MADS-box protein AGL82.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTU_ORYLA
Sequence: MEVGKKLELSITADEVEVLSKAIKNEKFQEMLSNYFQEISSPENVKTYQEEVTLLEQKRGNSIEFIHPSPFRALETSVDGKQRCFINICACDKVGKPESKTVRTVQRFGEKWSLPHLLQPGRQNCERKGNISTIYDVCFHPETLHLADKSEKFMDMVKEVAIQGIQKAFKVLLDKSNLKEMDIKYKGVPQSCVIRKPIPGYEAKEPPEERDLSPSTSHLPENSIDVPSKLLQKQPEEPIKPIYAIKYRSVIDLQDFRVSRESARSLRPKEIVITIDLPLLPTVHGMVLEVEEKRLLLESENPSYRLELHLSYPVDENNGKAKFNKHQRQLTVTLPVQPPLEAPQLPGGSPNPTSDPQNENQTRVEERVEEMAEKGGEQHQRGNDNGAAQGRRQVLEDQNGEKEGKKIQKRNERPEHEVKNETLRKKHDEKFELQDVQQENKGNCSNTKEVKCCRRTKDSLDSLIPTTAASPDGQKKHILTQETEKPKGSVEIPTSSQEYLKVPVTSAATAANVNASDETSKRKPTEEQLEDADEDVLPAEQRFQEPEEINVPAAGTLRQNNAAGNEKINDPHTSAGFVLQNKLMYELD
What is the function of this protein?
Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella.  Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.
What are the official names of this protein?
Protein kintoun, Dynein assembly factor 2, axonemal.
What is the protein family that this protein belongs to?
Belongs to the PIH1 family. Kintoun subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Dynein axonemal particle. Note=Localizes in the apical cytoplasm around the gamma-tubulin-positive pericentriolar region, not in the cilia.
Protein: QUEE_LEPIN
Sequence: MDNLKTSVHEIYLSLSGEGISTGIPTIFVRMAGCSLRCGMTVGRKLWCDTPYALSPKAGEEMSVNQVLDKIQELSAVNIQILLTGGEPLEGRNREFSITLGNEIFRIRNSSGFYPRPRVETNGAESIEGMDQFVFTLDYKLPGSGMEDRMNLKNLEIYKERKNPLDEIKFVIRDKNDFERCLEIIEKHALVGNLLASPVQGELSPEILAEWIKYSLGSGLRLSIQTHKYIWGDQRGV
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: JADE2_MOUSE
Sequence: MEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRLLPPLKGPPTQMSPDSPTLGEGAHPDWPGGSRYDLDEIDAYWLELLNSELKEMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCITAFHVTCAFDRGLEMRTILADNDEVKFKSLCQEHSDGGPRSEPTSEPVEPSQAVEDLEKVTLRKQRLQQLEENFYELVEPAEVAERLDLAEALVDFIYQYWKLKRRANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGKKNDSKRKGREGPKGSSPEKKEKVKAGPESVLGQLGLSTSFPIDGTFFNSWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPSPLQDGPSARTTPDKQPKKAWAQDGKGTQGPPMRKPPRRTSSHLPSSPAAGDCPVPATLESPPPLASEILDKTAPMASDLNVQVPGPTVSPKPLGRLRPPREMKVSRKSPGARSDAGTGLPSAVAERPKVSLHFDTEADGYFSDEEMSDSEVEAEDSGVQRASREAGAEEVVRMGVLAS
What is the function of this protein?
Scaffold subunit of some HBO1 complexes, which have a histone H4 acetyltransferase activity (By similarity).  Acts as a E3 ubiquitin-protein ligase mediating the ubiquitination and subsequent proteasomal degradation of target protein histone demethylase KDM1A (PubMed:25018020).  Also acts as a ubiquitin ligase E3 toward itself (PubMed:25018020).  Positive regulator of neurogenesis (PubMed:25018020).
What are the official names of this protein?
E3 ubiquitin-protein ligase Jade-2, Jade family PHD finger protein 2, PHD finger protein 15.
What is the protein family that this protein belongs to?
Belongs to the JADE family.
Protein: SYFA_ALIFM
Sequence: MQHLDEIIANATAEIEQAGSLVALDEVRVQYLGKKGHLTLQLQGLGKLDPSERREAGQLINKGKQAVQAMLTERKDALQTAELEAKLAAETIDVSLPGRRIENGGLHPVTRTVERIEQFFGELGFSTESGPEIEDAFHNFDALNIAEDHPARTDHDTFFFNPDLMLRTHTSGVQIRTMENGKPPFRFIAPGRVYRNDYDQTHTPMFHQVEGMLVDENVNFAQLKGILHDFLCNFFEEEVEVRFRPSFFPFTEPSAEVDVKRKDGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAR1_COCIM
Sequence: MSAILSADDLNDFISPGVACIKPVETLPAKSERDESAYEVTTEDKVAAENPSPAQISLTDCLACSGCVTSAEAVLISLQSHAEVLNTLDAYPELRVDGFRNGVQNGATGDARIFVASVSPQVRASMAATYGVSEKEAGYMIEQFLSGPQGLRAGGQHGSGFTWVVDTNVIRDVVLELTTDEVTASRAKFDSTATSESAEFPIPRQPILSSACPGWICYAEKTHPHVLPHLSRLKSPQALTGTFIKTILSKRLNVPPSRIWHLAIMPCFDKKLEASRQELTDASWQTTNHDIFASPAMDQPIRDVDCVITSRELLMLASSRNISLLTLPLTPLPSSFTTPFPDPRIAQFLFPKHHASNQSVSSGPSGGYLHHLLTTHQALHPNSTIQAQRGRNADVIDYTLVSAETGRPIIKAARYYGFRNIQNLVRKLKPAKTSRLPGARAAVSRRTGISASHTAAGGGVSDYAYIEVMACPGGCTNGGGQIRVEDARDTATIATSSIDGSAPTAQTSQHKPTPQEQRAWLARVDEVYYSADSDSHPPSSPSTSLGDEMEIDRPLEPESRSQSVHAILQYWSDMTGIPLPKLVYTTFRKVESDVGKSKNGAADTARVAELAGKIGGGW
What is the function of this protein?
Component of the cytosolic Fe/S protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins.  May play a role in the transfer of pre-assembled Fe/S clusters to target apoproteins (By similarity).
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NAR1, Nuclear architecture-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: IHFB_BURM9
Sequence: MTKSELVAQLASRFPQLVLKDADFAVKTMLDAMSDALSKGHRIEIRGFGSFGLNRRPARVGRNPKSGEKVQVPEKHVPHFKPGKELRERVDGRAGEPLKNDEPEDAQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: THIM_LISW6
Sequence: MFDFMTLEKVQERGPLVHNITNIVVANDSANGLLAIGASPIMASAKQEMDELAKMADVLVINIGMLDGELVEAMKIAGRAANFAETQVVLDPVGVGATSYRRKVVQELLAEIQFAAIRGNAGELAAIAGEAWEAKGVDAGVGSADVLAIAEKVAKEWNTVVIISGEVDVISDGTRFAKVANGSALLPRITGSGCLLSAVCGSFIAVQDDVFRASVEACVSYAVASEYAEMELERKLPGSFRPLFLDALASWSVEKTRAKAKILESGEHK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: RT106_ASPTN
Sequence: MAFATINSSAIPPATPSSIPTIEHAFASEPSLRKRVYDAIGATPQYIPLFEDIARYTSSLLARNATSTAPPAEASADGPAAKKRKIQNGDVSGTPQSLGDLKADAELQFHMRDVSFAMPQRKKLTLEVTAGGGFLRARNQTSKEVEFGVPVEKIQHVLCLPVPEKNQRQFNFCVIPQNGDGINTPAGGEAAPESIVWTVADGPPKSEFSINGQAVAGGAGGESAEKVVLRVLNDALTQTKVIRPDDREFVSAMPEAHRKGEKAYHVKAFRGSKEGYLFFLSTGILFGFKKPLIFFAFENIDSVSYTSVLQRTFNLNIMARATAGGEPQEFELSMIDQADFSGIDAYIKTHGLQDASLAEERRAKRYNINGKTEEAAAAANGDETAEEESELQKAQRELEDQEDEEEEDYDPGSDGDSDGSGSSSDDDDDDDDEHQDDEDDMDEDEDGEQDLVAAELGSQAADIPEDQV
What is the function of this protein?
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing.  Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA.  Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
What are the official names of this protein?
Histone chaperone rtt106.
What is the protein family that this protein belongs to?
Belongs to the RTT106 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GAG_SIVEK
Sequence: MGARASVLTGGKLDQWEKIYLRPGGKKKYMMKHLVWASRELERFACNPGLMDTAEGCAQLLRQLEPALKTGSEGLRSLFNTLAVLYCVHNNIKVQNTQEALEKLREKMKAEQKEPEPEQAAGAAAAPESSISRNYPLVQNAQGQMVHQPLSPRTLNAWVKVVEEKAFNPEVIPMFMALSEGATPQDLNTMLNTVGGHQAAMQMLKEVINEEAAEWDRGHPVHMGPIPPGQVREPRGSDIAGTTSTLAEQVAWMTANPPVPVGDIYRRWIVLGLNKIVRMYSPASILDIKQGPKETFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKNILRALGPGASLEEMMTACQGVGGPAHKARVLAEAMTQAQTATSVFMQRGNFKGIRKTIKCFNCGKEGHLARNCKAPRKKGCWKCGQEGHQMKDCRSGERQANFLGKVWPLSKGRPGNFPQTTTRKEPTAPPIESYGYQEEKTTQGTEREEKEKTESSLYPPLTSLKSLFGSDPSLQ
What is the function of this protein?
p6-gag plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p17]: Virion. Host nucleus. Host cytoplasm. Host cell membrane; Lipid-anchor. Note=Following virus entry, the nuclear localization signal (NLS) of the matrix protein participates with Vpr to the nuclear localization of the viral genome. During virus production, the nuclear export activity of the matrix protein counteracts the NLS to maintain the Gag and Gag-Pol polyproteins in the cytoplasm, thereby directing unspliced RNA to the plasma membrane (By similarity). SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: FTSA_STAAW
Sequence: MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDSEETEEDVIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQDKDKDKEESKFKKLMKSLFE
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: MANBA_EMENI
Sequence: MHFHGIATQAVLASNITTGSGRHVSLSDVKWTLSSSALNSTVPASLPSQAHLDLLNAGVIDDPYYGLNEIDLQWIAQANWTYTSDPIPDLLEEYESTWLVFEGLDTFATVTFCGHNIASTNNQFRQYAFDVSSALKECTGGPVVRIDFASAPNTVDAIAADPKTPVWPVQLTAQLPNRWLMRKQQSDFGWDWGPAFAPCGPWKPAYVVQLEKTAPIHVLNTDLDIYRQGNINHLPPDQKQPWVVNASIDFIGRLPAEPRLLIEIKELETGDVLASQISDSVTLIGTSITGVTTLKDASPKLWWPSSLGAQNLYNVTITVFNKTEEVARITKRTGFRTIFLNQRNITATQLSQGIAPGANWHFEVNGKEFYAKGSNFIPPDTFWPRVTKQKMTRLLDAVVAGNQNMLRIWSSGAYLPDFIYDLADERGILLWSEFQFSDSMYPVDEDFLDNVAQEVVYNVRRVNHHPSLALWAGGNEIESLMLPLTREADPDNYPKYLAEYEKLYISLILPLVYENTRSISYSPSSTTEGYLSVNLSAPVPMTERYENDEPGAYYGDTDYYNYDTTVSFDYSIYPVGRFANEFGFHSMPSLQTWQQVADPEDLYFNSTTVVIHNRHYTSEGYGRIENSSRGMAEMTLGVERYYPIPDNPDSVANFSAWCLATQLFQADFYKSQIQFYRRGSGMPERQLGSLYWQLEDIWQGPTWAGIEYDGRWKVLHYVARDVYQPIIVSPFWNYTTGDLEIYVTADLWESAAGTVNLKWLNLSGEQIIDNAGTPTEIPFTVGAINTTKVYSTNIHDLNLPDTRASILTLSLSSQANLPNAAVKTSLTHENHFTPSFPKDLELVNPGLELSYDAHSGIFTVEAKSGVSLYTWLDYPAGLVGYFTENAFLLVPGQKKKVQFVVQDGPKDQDWEWQSEVTVRSLWDQKSSTFLYALRVATGRP
What is the function of this protein?
Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length.  Involved in the degradation of polymeric mannan and galactomannan (By similarity).
What are the official names of this protein?
Beta-mannosidase A, Mannanase A, Mannase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family. Beta-mannosidase A subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TBXT_HUMAN
Sequence: MSSPGTESAGKSLQYRVDHLLSAVENELQAGSEKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKLNGGGQIMLNSLHKYEPRIHIVRVGGPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERSDHKEMMEEPGDSQQPGYSQWGWLLPGTSTLCPPANPHPQFGGALSLPSTHSCDRYPTLRSHRSSPYPSPYAHRNNSPTYSDNSPACLSMLQSHDNWSSLGMPAHPSMLPVSHNASPPTSSSQYPSLWSVSNGAVTPGSQAAAVSNGLGAQFFRGSPAHYTPLTHPVSAPSSSGSPLYEGAAAATDIVDSQYDAAAQGRLIASWTPVSPPSM
What is the function of this protein?
Involved in the transcriptional regulation of genes required for mesoderm formation and differentiation.  Binds to a palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence and activates gene transcription when bound to such a site.
What are the official names of this protein?
T-box transcription factor T, Brachyury protein, Protein T.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYF2_XENLA
Sequence: MDKEKAEVSPEEESAPASAEDLAAQKREARLRKFRELHLKTNEARKLNHQEVVEEDKRQKLPSNWEARKARLEWELKNEEKKRECAANGVDFERAKLLEISAEDAERWERKKKRKNPDLGFSDYAAAQLRQYQRLTKQIKPDMEEYEMEKEKQGELFYPTSDSLYHGTHVPSQSGIDRMVTDLEKQIEKREKYSRRRAYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.
What are the official names of this protein?
Pre-mRNA-splicing factor syf2.
What is the protein family that this protein belongs to?
Belongs to the SYF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: S39A7_HUMAN
Sequence: MARGLGAPHWVAVGLLTWATLGLLVAGLGGHDDLHDDLQEDFHGHSHRHSHEDFHHGHSHAHGHGHTHESIWHGHTHDHDHGHSHEDLHHGHSHGYSHESLYHRGHGHDHEHSHGGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLSFASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLWVLSGIVAFLVVEKFVRHVKGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETRGVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGGRGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGGAVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASPLQSLLEVLGLLGGVIMMVLIAHLE
What is the function of this protein?
Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels (PubMed:14525538, PubMed:15705588, PubMed:29980658, PubMed:28205653).  Acts as gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation (PubMed:29980658, PubMed:22317921, PubMed:28205653).  Has an essential role in B cell development and is required for proper B cell receptor signaling (PubMed:30718914).  Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function (By similarity).  Controls cell signaling pathways involved in glucose metabolism in skeletal muscle (By similarity).  Has a protective role against ER stress in differents biological contexts (PubMed:29980658, PubMed:30237509).  Mediates Zn(2+)-induced ferroptosis (PubMed:33608508).
What are the official names of this protein?
Zinc transporter SLC39A7, Histidine-rich membrane protein Ke4, Really interesting new gene 5 protein, Solute carrier family 39 member 7, Zrt-, Irt-like protein 7, ZIP7.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
Protein: TRXB_CHLMU
Sequence: MTHVKLAIIGSGPAGYTAAIYASRALLTPILFEGFFSGIAGGQLMTTTEVENFPGFPQGVLGHQLMENMKMQAQRFGTQVIAKDITSVDFSVRPFVLKSGEDTFTCDACIIATGASAKRLSIPGAGDNEFWQKGVTACAVCDGASPIFRDRDLFVIGGGDSALEEAMFLTRYGKRVFVVHRRDTLRASKAMVNKAQANEKIVFLWNSEVVKILGDSLVRSIDIFNNVEKTTVTMEAAGVFFAIGHQPNTAFLGGQLSLDENGYIITEKGSSRTSVPGVFAAGDVQDKYYRQAITSAGSGCMAALDAERFLEK
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_DICDI
Sequence: MTGTRTFFVGGNHKMNGSKSMLESLSKGMNESVENKENVDIFIAPSYPYLEFLSNKLDNKKFKVCSQNCYSVAKGAFTGEISANMLVDLGIPYVIIGHSERRNVFSESSELITKKTKYAISLGLTVILCLGELLADRKSNNTEHILSEQLKDFASFTPEEWSKIVIAYEPVWAIGTGAVATPQEAQDTHVFIRKWISEKVSEDVAKKTSIMYGGSVNADNCHNLSKQSDIDGFLVGGASLVASDFIAIIKSAVPKKY
What are the official names of this protein?
Triosephosphate isomerase, TIM, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
Protein: MRS2H_ORYSI
Sequence: MALPCAFLSAAAAANATSFSSSPESRRCRSVHRVPSRPRPPLAPPARVMGKGNSKRKAANTRLWMRLDRRGGCEMILCDKSFVARRSGLPARDLRVLGPLLSRSPSILAREKAMVINLEFVRAIVTADEVLVLEPLAQEVLPFVEKLRKHFPLKSLDVDDVSTHMHTENQDGELAQDVSCYEVEGANHELPFEFQVLDFALEAVCLSYNSTISDLNRSAIAVLDDLMKSVSTRNLERVRSLKSSLTRLLASVQKVRDEVEHILDDNEAMAHLCTARKTKGQKDLLNTILFPETRLCRTHSSIENSTGIRTCVPSDSDAHILDMLLEAYFKQLDGIRNRIFLVRQYIVDTEDYISIQLDNKRNELLGLQLTLIIASFGIAINTFIAAAFAMNIPHRGYHFVIGVPFGQFVGATSFLCMSIVILLFTYAWRNRLLCT
What is the function of this protein?
Putative magnesium transporter.
What are the official names of this protein?
Putative magnesium transporter MRS2-H.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HSLU_RICPR
Sequence: MKSTETTYKKDNMGLTPSQIVNELNRFIVGQDKAKKAVAIALRNRYRRKRVEGNLRNEIVPKNILMIGSTGVGKTEIARRLAKLTNSPFYKIEATKFTEVGYVGRDVESIIRDLVEIAVNTEKALAKIAVDINAREKAIERILDSLVGKTSSSETREKFKAKVLNGELDDTEIEISVADTTPVGGGGFEIPCIPGASMGVLNLGDMIGRALGNSKTKTKKMLIKDAMTVIIPEESEKLIDQEKIIQKAINLAENDGIVFIDEIDKIASTSNAGAKNAEISREGVQRDLLPLIEGTTVNTKYGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELNLLTKDDMIKILLEPETSLIKQYSALIGTEEVHLEFTDAAIEKIADYAITVNLEVEDIGARRLHTILENLLEDISFEASEMKVKKIIIDDKFVENQLSKIITNLDLAKFVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_ACIET
Sequence: MGKIIGIDLGTTNSCVAIMEGNNTRVIENSEGARTTPSIIAYQEDGEILVGASAKRQAVTNPKNTIYAAKRLIGRKFEEKEVQKDIDLMPFTITRADNGDAWVEVRGQKLAPPQISAEVLRKMKKTAEDFLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAFGLDKQDKGDRKIAVYDLGGGTFDVSIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRIIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSNSAQTDINLPYITADASGPKHLNIKLTRAKLESLVDELIERTIAPCRTAIKDAGISVSDINDVILVGGMTRMPKVQEKVKEFFGKEPRKDVNPDEAVAVGAAIQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMITKNTTIPTKFAQTFSTAEDNQPAVTIKVFQGEREIASANKLLGEFNLEGIPPASRGTPQIEVTFDIDANGILHVGAKDKGTGKENKITIKANSGLSEDEIQKMVKDAELNAADDKKKLELVQARNQGEAAVHTVNKSLSEHGDKLDAGEKEKIEAAVKDLEAALKTEDKAAIDEKTTALMAASQKLGEKMYGDAQAAQGAEAAAAQAAAGGSAGAAAQDDNVVDAEVKEVKKG
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YECM_ECOLI
Sequence: MANWQSIDELQDIASDLPRFIHALDELSRRLGLNITPLTADHISLRCHQNATAERWRRGFEQCGELLSENMINGRPICLFKLHEPVQVAHWQFSIVELPWPGEKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNPTLAVTDGKTTIKFHPWSIEEIVASEQSA
What are the official names of this protein?
Protein YecM.
What is the protein family that this protein belongs to?
To H.influenzae HI_1582/HI_1581.
Protein: MDM10_USTMA
Sequence: MHDFVSHILRQYFHATNWNEYNSYLHLTSCSSAILDFCVPTGLSLSISASPTPPFFTTYRLGALPNLRAGIGYIYASTDSKIDFGGSSKDVRLKEIIERFRIVEARAPAAFKSKEKEKEYYWLAGDRYPEQEALGDLGKKERGGGEYLVYGCMHVPSARLDALWTKRISPTWQLIVTAVSSPPRYPLNALQNAAIASRSAYSTGAKSTSSSMDRLDSSNPSLSSSTSLSNTGASTAATTAAAAAAAAAAQDTYGLGPPGSTNLQFTLQRDTGRWFTEYSYSIDDALWGFRVLHNFGTPADTASTTLAALSEGAVETSSSASYPQRNGSVLHTGSSSSSEDTEAGGGLRGRFSAGAEVFISTVEKSAGLSTGIRFSTLPDTPQQPLMIAPSFDSSPSPHQASTLASAPSQPPTVITATLNPMMGHLSTAYAARMARDVVVCSRFDFNVYSYESEWTMGAEYWLRKSGGGGGVESVEASDADVPAPMNRIGSTSSIGGLRGHDETRQARFQEEHAMSLREASEAVSQVDGNTGDGGTSVFGLLRDPPALAPSAPSPRATCANSTLSHLLSPITGVLKARISSTSDIRLLWQGRLSHCLVSLGVKADLSGTHGASYSVGGAPASPKMGIVKSIGLEVMYFSQAEDESVE
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: DEF_ECO81
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVEKLDRLKARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.