PharMolix/UniProtQA huggingface dataset:
Protein: CCD39_XENTR
Sequence: MNRKVLDELRWDDGYAIPVANAENKTLEEEMQKKEKEKIQLSNQVKGFEERIQAMADHLRNVRQELTYTQSLVRARENETESEEHFKTLSEREIGRLKQEIQRLENELVSLREKKNSHENNIFKTTQKLENLKRQLNWDQQTLEAWLEESARKDEDSMAIQKYSQKDDGKIKELSLLIEKLTLEAGQKRKLMDNELTETITAQIELDKTAEDFRKAHTERQQLISQWESTIGQMQKRDRDIDHCAMLLAQVKQELREKESIIKEKIQFLQSEIDNNKEYEKKISAAERQAAKLRLELQEQEIIRGRLQDELDSLKGVVDRTASDLETMRTEVTSLKKDIRNRQNRLQMAQEYNDGLSDKLNFVTESALSLEERALRMEEMFKEQEKTVKDLEVQLKQIREILFKKSQELHECKAKEKDVIAEINGGQVTLKNLNSQLQKLDSHALKQQGIMYNQDFQIQQLERRLSRLKGEVNTDEKQALEMRVSQLTKVFEERRAALKLLNTQHKKLQGDVRYIKRELEKTGQEKGDLISKKEEFNLFNMMSEKTLKKIKASKQDLMVEDNILKLEIKRLRDMLYSKADDVFSLEKRKLQLQTAMKERTEEISVHKEMLKSHIRYVDQERQNISSQLHERLAKVEKMRKRFEILTIAMMPPEGEEEKSQAYYVVKAAQEKEELQRVGDDLDGKIRKAEKEIRALENTLRVINGCNTSFKKSFSKITETSEEYDEKVQLEEEKKAAEEKHRYKQRQIRELQEDTQVMKNTFDSMINEELSYQEKAKELLPAITQLNKETEDQKQKLERVLKQYSKLSKHVRNAKKSKEETQEEKDINVRDLRDFNQSLNKMLAQAMEKNPDLATALQLYFHQFGLEIPTIGSTPGSYSSRSSSSRSSTISVRSGTSRISVNSGQSPRIKVVDLGLPPACPSSNVSSARSSRTSSRSGSSKSQKQE
What is the function of this protein?
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella.  Probably acts together with ccdc40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella.  Not required for outer dynein arm complexes assembly.
What are the official names of this protein?
Coiled-coil domain-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the CCDC39 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: ILVC_CUTAK
Sequence: MAKIYYDDDADLSIIQNRQVAVIGYGSQGHAHALNLRDSGVDVRVGLRDGSSSIAKAEAQGLRVLSIEDACEEADLIMVLVPDQNQRQLYAEHIAPHLKDGDALFFAHGFNVHFGYIKAPQGVDVCMVAPKGPGHIVRREYSDGRGVPVLVCVEQDASGIAWDLTRSYAKALGGLRAGGIETSFREETETDLFGEQAVLCGGLSHLIQAGFETLVTAGYQPEMAYFEVCHEMKMIVDLIIEGGISKLRWSISDTAEYGDYVSGPRVIDDHVKKNMKAVLDDIQNGAFAKRFIADQDAGAPQSKKFREGEAKHPIEATGKELRKMYSWLAAADDDYTEGSVAR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: K1HH_ANESU
Sequence: CENTISGCSRADCLLTHRKQGCQKTCGLC
What is the function of this protein?
This peptide is similar to the potassium channel toxin ShK, but does not show activity on potassium channels.  It appears that Lys-19, which is expected to occupy the pore of the channel, is not sufficiently accessible for binding, and therefore that this peptide must have a distinct functional role that does not involve potassium channels.  It is noteworthy that this peptide is much more stable in the presence of trypsin, chymotrypsin and pepsin than the toxin ShK.
What are the official names of this protein?
Ask132958, U-ASTX-Asu1.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1a subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: NUCS_PYRAB
Sequence: MRKVIIKENPSEEEIKELLDLAEKHGGVVTIFARCKVHYEGRAKSELGEGDRIIIIKPDGSFLIHQNKKREPVNWQPPGSKVTFKENSIISIRRRPYERLEVEIIEPYSLVVFLAEDYEELALTGSEAEMANLIFENPRVIEEGFKPIYREKPIRHGIVDVMGVDKDGNIVVLELKRRKADLHAVSQLKRYVDSLKEEYGENVRGILVAPSLTEGAKKLLEKEGLEFRKLEPPKKGNEKRSKQKTLDFFTP
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.  Binds to ssDNA.
What are the official names of this protein?
Endonuclease NucS, Nuclease for ssDNA.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3473_ARATH
Sequence: MALVMLARAPAPPLLLPSPNPPPCALPQDLTSLVSPSEPPDPPDPPDYLVGASNSFLSILLLRSSDLGSDLVQALSPLDLGFALRSITAVCSSWYQVFPLACLELWFSIPHLSHPLVTLSKGFVSLKGSNFFEFFTFFWNMPSFILQFPHHEDVMISTSFRLVLPQYEAVMILLKLKLFLPHYEDVLFSIGLRIQLLLPQYEVGLILYKLRLLLPHYEDVIQKLWLRAIHVIVSLVWFLEISRRIKEKTYDVLTRNDLGSWTPDLFIEKWWFSQPHTSPKLRFFSHLVGSRSWCFVAYAIVAVFHDAFYPLEDVASPDSRSPSVLSYFRKLISCFSTIGVSNFSCLTVMYVFIFFFRAFRMPFVAVVSLAFVASLMYLLNHFSIVGE
What are the official names of this protein?
Putative transmembrane protein At3g54730.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MED17_AEDAE
Sequence: MSVSANISVEAPIESQIQEIAYDGTEIYQLPPTLSEHLAKCAAKIDFSKTVNDLDLVKQSIKKEDEKKDDDSKDAAAHFQSSLWPWDSVRNKLKDAFTEVCVLSDVLAIAKEKRFMVLDPIPQEPPEVKQMVQVYARKKALASAANILLTGAERLKTAHTDQGGNRSAPDFHIELLRLRRNWRLKKVSNTIIGDLSYRTAGSKFMHPGMFEVTKAEDEDNNDENASAAAGTIATTGTAPEPKLTSLKVNVPTELQGVAFIKVITQKDQGDLCTATLNMMGSTQLFPQAGEWQKTLDFAQNVLFCKELFNQLAREAVQLQAPIPHVVVGNQIRATLLPGIQLVISLCHSTSSDSNNSSEPIKDHDHVLEHSLHQLLREFHHKNTHHPFPHPASAPLGPSKKRMLAGPSAFDRYELLEMTKSQTLLEQIIAQAQHIFTRRRAQYVLDTLAREVKDPQITSHWNAMNSPTMSCVKINITSHGYDANLRTSLVIHVKERSLKCICRDGRIMHMSYEMQELRDLILYQISQHQIVCLQSLAKCMAWQILSNSSHLGIGSVEPLGNASSCVLASPNSDRLIAVQVRCDPQLDVKVYIAQSPGKDFFPGSLVQGRHWEHLGGHFKELRFDKMEGKNFHNKMEFLMASLTSQT
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 17, Mediator complex subunit 17.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 17 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: US18_HCMVA
Sequence: MGDTASVSEHHESPTVTIVPLHRSHALVAEQQLFQWLKRFKLLMEVYHGLVWQLACTLTVCLLAWLAFPDVQGQCANGIVPALSSIVPVSTLAMLRGFAEFRPHTTNFAHLTVACLLINTGITVCTGFCGERRVIGLSFALVMVFFVLCSGLTYLAGNNPTRWKVIGIGYGWSVIVFYLLLYFSPVLWVSKIYSGLYVLVVTAASAVLIYETLDLIYQRGTLSKNSVCVSVVLYTIVMSLLNMSVAIFSGHVWVQQYAEKHGGRIDGVSLLSLL
What are the official names of this protein?
Transmembrane protein US18.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: LSPA_CAMJ8
Sequence: MAKTFKFIFYFWGAFVLVFVLDQWVKSLTLAGLRWQSEYLDLTYALNTGVAFSMLSFLEHNLKYLHLALIVVLFIYLFWQKTLLKTHSIAFGMMLGAGVSNLLDRFIHGGVVDMFFWHKWFNFAIFNVADVMINISVALILIQEIFKKRKKDDRMD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUOC_DEIRA
Sequence: MTAPDAGLPETNLRDTAARSTRRLAESRDVAPLLAELGLSAEEGLQPTAAVEAGELLHTAQQLRARGFMLLDVIGVDYSRYTAPRPQPFAVLYSVAHPRDHRRLFLRVWLSEGEAVDSLFPIWKAANYLEREVYDLLGIEFTGHPDLRKVLTPDDLEGHPLRKDFPLGETPTLFREGRFLDPAAFRAGLSGQQRGLTGYRGEMRRGERRREDIVPPLLPEGGPK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ADE_CAUVC
Sequence: MTDASFAPSASAEFVRGLPKAELHMHIEGSLEPELMFELAQRNGITLPFASVEEIRAAYDFSNLQDFLDIYYQGAGVLITEADFKDLALAYFQRLAADGGAHAEIFFDPQTHTDRGIAFDTVMNGLLAGMDEAEKTLGVTSKLILCFLRHLSEEAAFETLEQAKPWLAKLAGVGLDSSEVGHPPAKFARVLQASRDLGLKVVAHAGEEGPPAYVWEAIDLVKVDRIDHGNRALEDEALTARLVKDGITLTVCPLSNLKLCGVPSLDVHPLKRMLDLGLKATVNSDDPAYFGGYLLENYLATADAVGLTRDDIVTLAKNSFAGSFLTDAEKAQRIAAVEAYAAAH
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: KTHY_CWPXG
Sequence: MSRGALIVFEGLDKSGKTTQCMNIMESIPSNTIKYLNFPQRSTVTGKMIDDYLTRKKTYNDHIVNLLFCANRWEFASFIQEQLEQGITLIVDRYAFSGVAYAAAKGASMTLSKSYESGLPKPDLVIFLESGSKEINRNVGEEIYEDVEFQQKVLQEYKKMIEEGDIHWQIISSEFEEDVKKELIKNIVIEAIHTVTGPVGQLWM
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: POZP3_HUMAN
Sequence: MVCSPVTLRIAPPDRRFSRSAIPEQIISSTLSSPSSNAPDPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRSCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGLADICQCCNKGDCGTPSHSRRQPRVVSQWSTSASL
What are the official names of this protein?
POM121 and ZP3 fusion protein, POM-ZP3.
Protein: CSRA_STUS1
Sequence: MLILTRRVGETLMVGDDVTVTVLGVKGNQVRIGVNAPKEVAVHREEIYQRIQKEKDQEPSH
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: CTF8_YEAST
Sequence: MPSVDIDASQWQKLTQSREKQTTVITPLGMMMLEIQGELELPKDFASLARRDSPNEGRFSEQDGETLIRFGSLQIDGERATLFVGKKQRLLGKVTKLDVPMGIMHFNSKDNKVELVDVMKYKVIFKDRPLPIM
What is the function of this protein?
Essential for the fidelity of chromosome transmission.  Required for the DNA replication block checkpoint.  Component of the RFC-like complex CTF18-RFC which is required for efficient establishment of chromosome cohesion during S-phase and may load or unload POL30/PCNA.  During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC.  The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit.  Dissociation of RFC from the clamp leaves the clamp encircling DNA.
What are the official names of this protein?
Chromosome transmission fidelity protein 8.
What is the protein family that this protein belongs to?
Belongs to the CTF8 family.
Protein: ADC_BURO1
Sequence: MKPSDVRSKAFAMPLTSPAFPMGPYRFVDREFLIITYRTDPDRLREIVPEPLQVTEPLVHYEFIRMADSTGFGDYTESGQVIPVEYEGQPGGYTLAMYLDDHPPIAGGRELWGFPKKLASPTLHVNTDHILGTLDYGKVRVATGTMGYKHKELDIDEQTKRLAGPNFLLKIIPHVDGTARVCELVRYYMQDIKMKGAWTGPASLELAPHALAPVADLPVLEIVEARHLVADLTLGLGEVVYDYLAQ
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: KTHY_VACCC
Sequence: MSRGALIVFEGLDKSGKTTQCMNIMESIPANTIKYLNFPQRSTVTGKMIDDYLTRKKTYNDHIVNLLFCANRWEFASFIQEQLEQGITLIVDRYAFSGVAYAAAKGASMTLSKSYESGLPKPDLVIFLESGSKEINRNVGEEIYEDVTFQQKVLQEYKKMIEEGDIHWQIISSEFEEDVKKELIKNIVIEAIHTVTGPVGQLWM
What is the function of this protein?
Poxvirus TMP kinase is able to phosphorylate dTMP, dUMP and also dGMP from any purine and pyrimidine nucleoside triphosphate.  The large substrate specificity is explained by the presence of a canal connecting the edge of the dimer interface to the TMP base binding pocket, canal not found in the human homolog.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DLGD_MANSM
Sequence: MKVSYEELKSEFKRVLLSRNVREDIAEECATVFADTTQAGAYSHGVNRFPRFIQQLENGDIKPEAQPTKVLSLGAIEQWDAHQAIGNLTAKKMMDRAMELASQNGVGIVALRNANHWMRGGSYGWQAAEKGYIGICWTNALAVMPPWGAKECRIGTNPLIVAVPTTPITMVDMSCSMYSYGMLEVHRLQGRQTFVDAGFDDNNNPTRDPATVEKNRRLMPMGFWKGSGLSIVLDMIATLLSNGESTAAVTEDKDDEYCVSQVFIAIEVDRLIDGKTKDEKLNRIMDYVKTAEPVDPNQPVRLPGHEFTTILADNKANGIPVDDTVWAKLKSL
What is the function of this protein?
Catalyzes the reduction of 2,3-diketo-L-gulonate in the presence of NADH, to form 3-keto-L-gulonate.
What are the official names of this protein?
2,3-diketo-L-gulonate reductase, 2,3-DKG reductase, 3-dehydro-L-gulonate 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH2/MDH2 oxidoreductase family. DlgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_ECOSM
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPE_XANOM
Sequence: MDRIALMNAPGTDWSAWPAPAKLNLFLQITGRRADGYHLLQTVFRLLDWGDTIHLRVRSDGQILRIGESLPGVAEDDDLVIRAARLLQSAAGAAAGAEIRVDKRIPAGGGFGGGSSDAATVLVALNALWGLALTADTLAELGLQLGADVPVFVRGRNAWAEGVGEQLTPIALPEAAYLLVDPGVHVPTPVLFRSQELTRDAAPAKITDFASGSLLDNAFEPVLRRREPAVEAVFQALSRVGTPRLTGSGSGCFVEFATRAAAEQALAQLPGSLRAWVVEGAAHSPLLDARDAMKV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TIG_SULNB
Sequence: MKVEVKKIDDANVAVQGNIENKVVEANVDKLAREAGKQMKVDGFRKGKVPPHVVKKLHGDKLQQDAEGDALRSLIDLGVKEAGINTADILGEPIFKKYDKKDEGIEVEVEISLRPTIEAEGYEKAVPAFEKPEATEKEVEEKLEEIAAQQAPFEKIKRKRMVRDGDTVVIDFEGFVDGVAFEGGKAEKFSLKIGSGQFIPGFEEQIIGMKYDEEKTITVAFPEEYQSKELAGKEAEFKVKLHEIQEQVPAELNDALAQKLLQDEKATLDTLKEKLKEQIVNEKTSKIYNEELKPKIIEALVAHFDFALPNNIVEQEIDAKINAKAREMSEEELNDFKENPEKVEALREELREEAENSVKATFIVDALAKKEDVNVDDQEVSQAIYYEAMMSGQDPQQVIEYYQKNNLLPAVKMGMIEDKLFGKLLGL
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RS12_WIGBR
Sequence: MVTINQLVRKSRSNKIIKTNVPALSSCPQKRGVCIRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSSVLIRGGRVKDLPGVRYHIVRGALDCAGVKNRKKARSKYGVKKIKNK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DAPA_ACAM1
Sequence: MTFFGQILTAMVTPFTDTGDMNFSVAEALAIHLADHGTDTLLLCGTTGESPTLTWQEEYELFQVVRKAVASKAKVMAGTGSNSTREAIEATQQAAKLGLDGALLVVPYYNKPPQEGLYEHFRAIAESVPDFPLMLYNIPGRTGQNLEADTVARLAEIGNIVAIKEASGNLDQVSQIRRLTPPEFSIYSGDDSLTLPYLSVGAAGVVSVASHLVGELLQKMVTAFASGEPQVATEIHLKLLPLCKALFATTNPIPVKAALQLQGWQVGSTRLPLPEAPDPIIQKLKNTLTDLALL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_LACPL
Sequence: MAQSIVEAPIRVDTSRKIIHVDMDAFYASIEEREHPAYKTQPLVIAHDPRQTGGRGVVTTANYVARQFGVHSAMPAAKALELCPTAVFKTPNFPLYREVSAQIHRIFHEYTEMIEPIAFDEAYLDVTTNKKHIHSAVELAHRLQQEIWHQTHLTCSTGISYNKFIAKLASDYRKPAGVTIVLPQDAEPFLLREPIEKFRGVGKKTVPKMHDLGIKTGQDLYAQSELDLIKQFGKLGYILYRRVRGSDDRPVEYLRERKSIGKERTFGPFLQSTTEVNTHLKAIAKLVAASMQSHQRHGKTLVLKLRYGDFVTITKRRTFGEFIPNDAALFEQYAEEIFEEVVDDHFNSGIRLLGITLTGLAPLAFENLTLPLYPNDN
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATRF2_STAA1
Sequence: MTEKEKMLAEKWYDANFDQDLINERARAKDICFELNHTKPSDTNKRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFYHRNEGYEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK
What are the official names of this protein?
Putative acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: TRI68_MOUSE
Sequence: MDPAVLMEAIVEEVNCPICMTFLREPVSISCGHTFCHSCLSGLWKLPGESQNLSYTCPLCRAPVKPRKLRPNWQLASVVDKVRLLGFCMEMGLKTDVCDLHKEQLTMFCKEDDMVTCEACKQSPEHEAHSVVPIKDVAWEYKWKLQQALEHLRKEQEEAWKLEVSEKEQAAIWKTQMERRKQSIRWEFEKYRQLLKEKELPCQQAEEEAAAAQASLEQEKGETASKLELRREAIIRQSQVLWSMIVELEERSQRPVRWMLQGIQEALNRSESWTLQQLEPISLELKTDCRVLGLRETLKTFAVDVRLDPDTAYSRLVVSKDRKSVHYGVTQQNLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCVENVDRKEVVYLSPRYGFWVIRLRKGTEYRAGTDEYPLLPLTVPPHRVGIFLDYEAHDISFYNVTDGASHIFTFPCYPFPGRLLPYFSPCYSIDTNNTTPLTICTLGGEG
What is the function of this protein?
Functions as a ubiquitin E3 ligase.  Acts as a coactivator of androgen receptor (AR) depending on its ubiquitin ligase activity.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM68, RING finger protein 137, RING-type E3 ubiquitin transferase TRIM68, Tripartite motif-containing protein 68.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus. Note=Colocalized with AR in nucleus.
Protein: CINA_CITBR
Sequence: MTATVASTSLFTTADHYHTPLGPDGTPHAFFEALRDEAETTPIGWSEAYGGHWVVAGYKEIQAVIQNTKAFSNKGVTFPRYETGEFELMMAGQDDPVHKKYRQLVAKPFSPEATDLFTEQLRQSTNDLIDARIELGEGDAATWLANEIPARLTAILLGLPPEDGDTYRRWVWAITHVENPEEGAEIFAELVAHARTLIAERRTNPGNDIMSRVIMSKIDGESLSEDDLIGFFTILLLGGIDNTARFLSSVFWRLAWDIELRRRLIAHPELIPNAVDELLRFYGPAMVGRLVTQEVTVGDITMKPGQTAMLWFPIASRDRSAFDSPDNIVIERTPNRHLSLGHGIHRCLGAHLIRVEARVAITEFLKRIPEFSLDPNKECEWLMGQVAGMLHVPIIFPKGKRLSE
What is the function of this protein?
Involved in the degradation of cineol (eucalyptol).  Catalyzes the initial hydroxylation of cineole exclusively at the pro-R carbon to give the (S)-6beta-hydroxycineole.  Cineole is the natural substrate of CinA.
What are the official names of this protein?
1,8-cineole 2-endo-monooxygenase, cytochrome P450, CYP176A1, P450cin.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: MURG_CHLTE
Sequence: MKVLFAGGGTGGHLYPGVAMAAELKKRVPGISISFAGTSAGIEATEVPRLGYRLVLFPVRGLKRGLSIRALVENALILGDFAKSLSMAMALVRKEQPDVVVGTGGYVSAPLLLAAQLSGKKTLIQEQNAFPGVTTRLLARMATEVHLSFEESRKFFGGKSEVFVTGNPAREFPAESRESCLDFFGLDRSLPTLLVFGGSRGARAINNAVLKLCHRLEGTVNLIWQTGALDADRMRGEIGTSATRWIGPYIQEMGKAYGAADLVLCRAGASSLAELTNLGKPSVLIPYPYAAADHQRHNAMALVSAGASVMIDDSKIGEEASFDVILTLLRDREKLAQMGEAARREGHPGAAATLAERIIALSKS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.