PharMolix/UniProtQA huggingface dataset:
Protein: PAND_CHRSD
Sequence: MYTIMLKAKLHMARVTHAVLDYEGSCAIDGELLDLAGIRENEQIQIYDVENGNRFTTYAIRGEAGSRLISINGAAAHQAQVGDRVIICSYAHYAEHELATHQPALVYLQDGNQISHTSHAIPVQFA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAK6_HUMAN
Sequence: MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRITRVQLQPMKTVVRGSAMPVDGYISGLLNDIQKLSVISSNTLRGRSPTSRRRAQSLGLLGDEHWATDPDMYLQSPQSERTDPHGLYLSCNGGTPAGHKQMPWPEPQSPRVLPNGLAAKAQSLGPAEFQGASQRCLQLGACLQSSPPGASPPTGTNRHGMKAAKHGSEEARPQSCLVGSATGRPGGEGSPSPKTRESSLKRRLFRSMFLSTAATAPPSSSKPGPPPQSKPNSSFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQKSLRTAPATGQLPGRSSPAGSPRTWHAQISTSNLYLPQDPTVAKGALAGEDTGVVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVLRDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLIQLYRKQTSTC
What is the function of this protein?
Serine/threonine protein kinase that plays a role in the regulation of gene transcription.  The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6.  Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription.  Inhibits also ESR1-mediated transcription.  May play a role in cytoskeleton regulation by interacting with IQGAP1.  May protect cells from apoptosis through phosphorylation of BAD.
What are the official names of this protein?
Serine/threonine-protein kinase PAK 6, PAK-5, p21-activated kinase 6, PAK-6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Cotranslocates into nucleus with AR in response to androgen induction.
Protein: VP7_BROAA
Sequence: VAIRIIWSDIQD
What are the official names of this protein?
Venom peptide 7, BaP-7.
What are the subcellular locations of this protein?
Secreted.
Protein: FAD3_RICPR
Sequence: MQNEIKKVCVIGAGVMGSGIAALIANSSHQVVLLDILDKDSNDPNKIVKNSVKNLHKQKLSPLSFPDKVNFITIGNLEHDLDLIKECNLVIEVIVEKLEIKHQLYNKIIPYLKEDAIIASNTSTLPLKKLKVNLPNNIKSRFVITHFFNPPRYMELVELIIDHTIKDEVIEKVSVFLTKMLGKTIIKCNDTPGFIANRVGCFLLELVVHKAIAQNLNFVTIDQIFSRCLGLPNTGIFGLYDLIGHDVMKLISSSLISALPKSDDYHRIYTNTKVFDKMIEHNLIGRKGEGGFYRLSVSNGKKIKEVINISDLSYHPVQKVDISFNSLNELLSSNSIYGKFFSEIITEFYIYLTSLVPSVTNNIYDIDTTMKLGYSWHYGPFELLTIAVKNGWNLIIKNADLMNIPLPKYLASKEYQKIDKQKFNSKKDFLQESKIVLSNDSANLIHYCENLVFVITTKMNSLNHNVFYLLQEAVSKAENYGKNLYIYPQGNNFSAGADLKLILSYIQDGNFHNLENLLKLGQQTMRYLKYSSVHIISCARGVALGGGCELLLNSSYIVANQELNAGLIELGVGLIPGWTGVTEMFARSNGNKTKLIRNIKNIIEQNKTSSADYFKADYGIKNMQVNMNKHYILDDALKLRISKKIVSIPNKITLPKINIVSEIDTSKYNELQNKVLNKFQNIIDKHNEISEAELLTYEREMFLELAKTPQTIEKLQAIVG
What are the official names of this protein?
Putative fatty acid oxidation complex trifunctional enzyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
Protein: PESC_YARLI
Sequence: MGQIKKKHTAGAARNFITRTQAIRKLQVSLADFRRLCIFKGIYPREPRSKKKANKGSTAPVTFYYAKDIQYLLHEPVLDKFREHKTFAKKLTRALGRGDLHDAKRIDENRPRYHLDHIIKERYPTFMDALRDIDDALSMLFLFAALPASDDVSARLVSEAEAICTQWMAFVARERLVRKVFVSIKGVYYSANIRGVEVMWLVPFRFPQNIPADIDFRVMLTFLEFYTTLLHFVLYKLYNENGLVFPPIINSTKLSGVGGINAYVLESRQNAGVVPQIEGNSEAKVENVSAAVLSKAAKADAGEEEEVEEEEEVEDDGLDSFSAEKGDALAQPTFNSTAGQLFSNFTIFIGREVPLDIIEFLIIAFGGKVISESAMDELIDNEDETRGNVIDEKTLKQKFNLASVTHQITDRPTLREKVPGRTYVQPQWVFDSINEGKLLPVSEYAPGERLPAHLSPWGDAGTYDPTADVSDASDDDEDDEDIEVAPEDYDKDDEEEEAEAEAKQHQRELEAEAKGTKADPAAAPKKAKRKADKMTKAEKQEEEDKKLRMIMMSNKQKKLYKKMQYSNDKKSDREAELKKRRKLNEKKEKR
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Pescadillo homolog, Nucleolar protein 7 homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: CYSC_ECOK1
Sequence: MALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: Y368_BRUSI
Sequence: MRSTKVIHIVGCHAEGEVGDVIVGGVAPPPGETVWEQSRFIANDETLRNFVLNEPRGGVFRHVNLLVPPKDPRAQMGFIIMEPADTPPMSGSNSICVSTVLLDSGIIAMQEPVTHMVLEAPGGIIEVEAECRNGKAERISVRNVPSFADRLDAPLDVTGLGTIMVDTAYGGDSFVIVDAAQIGMKIEPGQARELAEIGVKITKAANEQLGFRHPERDWRHISFCQITEPVTREGDVLTGVNTVAIRPAKLDRSPTGTGCSARMAVLHAKGQMKAGERFIGKSVLGTEFHCRLDKVLELGGKPAISPIISGRAWVTGTSQLMLDPSDPFPHGYRLSDTWPRDE
What are the official names of this protein?
Uncharacterized protein BSUIS_A0368.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: TMCAL_LISW6
Sequence: MKATGIVVEYNPFHNGHQLHLNKARELTKADVVIAVMSGSFVQRGEPAILPKWERTKMALAAGVDMVVELPVSFATQHATIFAEESVRILDALHVDALFFGSEHGVSEDFLTAAKTVVEHEASFNQAIQLALIDKKTSYARAYTETFKQSFGTELLDVTKPNNILGFHYALAIQKQNPTISLQTMARIHAGYHDIEANHDQIASATAIRKLLLAGNLEEASRYLPASSIEILKNYDGPFLSWENYWALLKYRLIQAETDELEGIRNVSEGIQNRMQIAATKAQYFSDFIESMKTKRYSNARIQRTALQILLNARNIPSAPYIRILGMNKTGQKYLSHHKKNISLPIVTTVSKAAPGLLEEDLRATNIYTLVKGLENYQAGDFHIPPILKSQT
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VEGFA_HUMAN
Sequence: MNFLLSWVHWSLALLLYLHHAKWSQAAPMAEGGGQNHHEVVKFMDVYQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPTEESNITMQIMRIKPHQGQHIGEMSFLQHNKCECRPKKDRARQEKKSVRGKGKGQKRKRKKSRYKSWSVYVGARCCLMPWSLPGPHPCGPCSERRKHLFVQDPQTCKCSCKNTDSRCKARQLELNERTCRCDKPRR
What is the function of this protein?
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth.  Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.  Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin.  NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145.  Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.  Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity).  Also binds the DEAR/FBXW7-AS1 receptor (PubMed:17446437).
What are the official names of this protein?
Vascular endothelial growth factor A, VEGF-A, Vascular permeability factor, VPF.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Secreted. Note=VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin- binding properties and, although a significant proportion remains cell- associated, most is freely secreted. VEGF189 is very basic, it is cell- associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin.
Protein: HIS7_LACCB
Sequence: MRTATITRTTKETTITISLNLDQQSGIQIATGIGFFDHMLDAFAKHGRFGLTVDAQGDLDVDPHHTIEDTGIVLGECFKQALGDKAGIERFGSAFVPMDESLARAVVDLSGRAYLVFDAELTNQRLGGFDTEVTEDFFQAVAFAGEFNLHASVLYGRNTHHKIEALFKALGRSLRAAVAINPEVQGIPSTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRSA_SHIBS
Sequence: MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEAAQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIVMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDKGLQEITGWIEKRLC
What is the function of this protein?
Catalyzes the hydrolysis of esters.
What are the official names of this protein?
Esterase FrsA.
What is the protein family that this protein belongs to?
Belongs to the FrsA family.
Protein: ACSF3_MOUSE
Sequence: MPPHLALPFRRLFWSLASSQLIPRRHRGHSLLPTTPEAHTDGSVPVFIRALAFGDRIALIDKYGHHTYRELYDRSLCLAQEICRLQGCKVGDLQEERVSFLCSNDVSYVVAQWASWMSGGVAVPLYWKHPEAQLEYFIQDSRSSLVVVGQEYLERLSPLAQRLGVPLLPLTPAVYHGATEKPTEQPVEESGWRDRGAMIFYTSGTTGRPKGALSTHRNLAAVVTGLVHSWAWTKNDVILHVLPLHHVHGVVNKLLCPLWVGATCVMLPEFSAQQVWEKFLSSEAPQITVFMAVPTVYSKLLDYYDKHFTQPHVQDFVRAVCKERIRLMVSGSAALPVPLLEKWRSATGHTLLERYGMTEIGMALSNPLTEARVPGSVGTPLPGVEVRIISENPQKGSPYIIHAEGNERGTKVTPGFEEKEGELLVRGPSVFREYWDKPEETKSAFTSDGWFRTGDTAVFKDARYWIRGRTSVDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDMTWGQRVTAVVALQEGHSLSHGDLKEWARGVLAPYAVPSELLLVEEIPRNQMGKVNKKELLKQLYPSGQRSQPGQG
What is the function of this protein?
Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester.  May have some preference toward very-long-chain substrates.
What are the official names of this protein?
Malonate--CoA ligase ACSF3, mitochondrial, Acyl-CoA synthetase family member 3.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CLPP_STAA3
Sequence: MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_SODGM
Sequence: MLAKRIIPCLDVRQGQVVKGVQFRNHEIIGGIVPLVCRYAEEGADELVFYDITASADARVVDKRWIADVAEVIDIPFCVAGGIQSVAQAGEILSYGADKISINSPALADPTLISRLADRFGVQCIVVGIDTWFDAASGRYQVNQYTGDETRTHITPWQTLDWIEEVQRRGAGELVLNMMNQDGVRNGYDLMQLRQVRERCHVPLIASGGAGTMAHFLSAFRDAQVDGALAASVFHKQIINIGELKQFLAAEGVEIRLC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_STRPZ
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQVDYLEELVNKYPIITIEDGMDENDWDGWKVLTERLGKRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: EI3D2_DROPE
Sequence: MSGRAPFIKPVLEYNEHGWGPCEELSVDVPYQPFCKSDRVGKISDWTAPPTERKFANKYVSSFGNSNQYAYFHEDDESTYHLVDTSGFKGFRPFQRGRFRGNIRNNPRTRGRTGRGGAVTGIGGNQPGVGVNERTKYGKGRDNRRQMGRRFGRNAPTRMRESSVVVRSDWVSIEEIDFPRLLKLSLPNVKEGQDVVTCGSLEYYDKTYDRINVKNERPLLKTDRIIHTLTTTDDPVIRRLSKTIGNIFATDEILATIMCCTRSNYSWDVVFDKVGNKIFLDKRDNAQFDLLTVNETALEPPLDEEGSINSPHSLAMEATLINHNFCQQVLRGGDQKKYQFEEPYPLEESGVDLVSIGYRYKQWDLGNNIILIARCKHNGVLQGPNGEVQFLSIRALNEWDSKASNSLEWRQKLDTQHGAVLASELRNNACKLARWTVESVLSGSDQLKLGYVSRVIPRDHLRHVILRTQQFKPQEFSTQINLSMDNAWGILRCLIDIVMKQPDGKYLLMKDPNKPMVRLYDVPENAFESSDEDDLSDDKLFLLSN
What is the function of this protein?
mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit D-2, eIF3d-2, Eukaryotic translation initiation factor 3 subunit 7-2.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_KORVE
Sequence: MPKLKTHSGAAKRFKKTATGKVKRSKAFKRHILTSKSTKKKRHFDMEGLVSKADTPKIKRMIPY
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: FAAH_ORYSI
Sequence: MGKPPRAMTPVEEVDLSAVRYQSPSLQAPHLTGFSLRAFVWLMESPLFGRLLTSVLKSQNNITRMLQDTVIPERPMYLPEYPPQEPEQGVLLLGDDRDPVDRVEEALHCLPPYDPSLRWPAGDKPPFLYWKIRDFAHAYRSGITTPSVVAEHIIAGVEEWSNKKPPMPMLVYFNADDLRKQAEASTKRFQQGNPISILDGIFIAIKDDIDCFPYPSKGATTFFDKIRSVEKDAVCVARLRKCGVLFIGKANMHELGLGVTGNNPNYGTARNPHSIDRYTGGSSSGPAALVSSGLCSAAIGTDGGGSVRIPSSLCGIIGLKTTYGRTDMTGALCDCGTVEVASPLAASVEDALLVYSAIAGSRPMDKLTLRPSPLCVPNLVSPDNNNILGSVKIGKYTEWFHDVSDRDISNTCEDALNLLCSSFGCQIEEIILPELEEMRTAHVVSIGTESFCDLNPHYRAGKRTEFTLDTRTSLALFGSFTSTDYVASQRIRRRIMYYHNEAFKKVDVIATPTTGITAPEIPQSSLKLGESNYVVSAYLMRFVIAGNLLGLPAITVPVGHDKQGLPIGLQLIGRPWGEASLLRVASAIEELCLKKRKRPSAFHDILNA
What is the function of this protein?
Catalyzes the hydrolysis of bioactive endogenous fatty acid amides to their corresponding acids.  The hydrolysis of endogenous amidated lipids terminates their participation as lipid mediators in various signaling systems.  Converts a wide range of N-acylethanolamines (NAEs) to their corresponding free fatty acids and ethanolamine.
What are the official names of this protein?
Fatty acid amide hydrolase, N-acylethanolamine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Cell membrane.
Protein: CH604_RHILO
Sequence: MAAKDVKFSRDARERMLRGVNILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVTVAKEIELEDKFENMGAQMVREVASKTNDIAGDGTTTATVLAQSIVQEGHKAVAAGMNPMDLKRGIDLAVSEVVAALGKAAKKIKTSEEVAQVGTISANGDESVGKMIAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNADKMVADLEDAYILLHEKKLSNLQAMLPVLEAVVQTSKPLLIISEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGIKLENVGLNMLGRAKKVSISKENTTIVDGAGKKAEIQGRVAQIKQQIEETTSDYDKEKLQERLAKLAGGVAVIRVGGATEVEVKEKKDRVDDALNATRAAVEEGIVAGGGVALLRASANIKAAGANADQAAGINIVRRALQAPARQIASNAGAEASIVAGKILENKGATFGYNAQTGEYGDMIAMGIVDPVKVVRTALQDAASVAGLLVTTEAMIAEAPKKESAGGGMPGGMGGGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 4, 60 kDa chaperonin 4, Chaperonin-60 4, Cpn60 4.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_COREF
Sequence: MADSYLHAPTLVRATTPLVQCLTNAVVMQFTANALLAIGASPAMVDTPAESFDFAGVADGVLINAGTPSAEQYAGMERAIEGATAAGTPWVLDPVGVGGLAERSAFLRRAVDKHPAAIRGNASEIVALAGLGAGGRGVDATDDVADAVEAAQVLARRTGGVVAVTGAEDLIVSRGRVSWLKSGDPMLQLVIGTGCALGAVTAAYLGATQDTDIDPHDAVVAAHAHLGAAGRIAATRATAPGSYAVALIDALHQLDRNQLANLTHLREENR
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: Y112_HELPJ
Sequence: MYRRLLLNLFCMVFLQACLKPMSDPKAEKVDSQVQCGFGSKDC
What are the official names of this protein?
Uncharacterized protein jhp_0112.
Protein: CHLB_PORPU
Sequence: MKLAYWMYAGPAHIGTLRVASSFKKVHAIMHAPLGDDYFNVMRSMLERDRDFTPVTASVVDRHVLARGSQEKVVENITRKDREEKPDLVILTPTCTSSILQEDLQNFVSRASIETEADVLLADVNHYRVNELQASDRTLEQIVTFYMEKAKSNNILTKKTIKPSVNIIGAVSLGFHNQHDIAELKRLFHDLDIQINQVIPENASVHDLKNLPSAWFNFVPYRETGLMTALYLKKEFNMPYIDITPMGIVQTATSIRSIQKILNALGATVNYEKYIDEQTRFISQSAWFSRSIDCQNLTGKKAIVFGDATHAAAITRILHQEMGIHVAWCGTYCKYDEEWFREQVKGFCDEVIISDDHGLIGDLIAKTEPAAIFGTQMERHIGKRLNIPCGVISSPVHIQNFPLSYRPFLGYEGTNQIADLVYNSFTLGMEDHLLEIFGGHDTTEALSVGISADDSLNWSDEAQKELSKIPGFVRGKVKRNTEKFARDCSKNLITLELMYEAKEKVSS
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (ChlN-ChlB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS9_UREP2
Sequence: MQKSNIVEYKGLGRRKSSIARVKLVPGSGKVLVNDRQPENYFPNKLVIQDMMQPLVLTKTAETYDVYVKVIGGGFNGQAGAIRLGITRALIQTREDLKTDLRKAGLVTRDSRVKERKKFGLYGARRAPQFTKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ACCH5_ARATH
Sequence: MGHDSFCYLIVLRCALRCGIIALMQICALQKKERRSKMESSDRSSQAKAFDETKTGVKGLVASGIKEIPAMFHTPPDTLTSLKQTAPPSQQLTIPTVDLKGGSMDLISRRSVVEKIGDAAERWGFFQVVNHGISVEVMERMKEGIRRFHEQDPEVKKRFYSRDHTRDVLYYSNIDLHTCNKAANWRDTLACYMAPDPPKLQDLPAVCGEIMMEYSKQLMTLGEFLFELLSEALGLNPNHLKDMGCAKSHIMFGQYYPPCPQPDLTLGISKHTDFSFITILLQDNIGGLQVIHDQCWVDVSPVPGALVINIGDLLQLISNDKFISAEHRVIANGSSEPRISMPCFVSTFMKPNPRIYGPIKELLSEQNPAKYRDLTITEFSNTFRSQTISHPALHHFRI
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase homolog 5.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: GUAA_PONAB
Sequence: MALCNGDSKLENAGGDLKDGRHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMSLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETSNILKIVADFSASVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
What is the function of this protein?
Catalyzes the conversion of xanthine monophosphate (XMP) to GMP in the presence of glutamine and ATP through an adenyl-XMP intermediate.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ANGI_MOUSE
Sequence: MAISPGPLFLIFVLGLVVIPPTLAQDDSRYTKFLTQHHDAKPKGRDDRYCERMMKRRSLTSPCKDVNTFIHGNKSNIKAICGANGSPYRENLRMSKSPFQVTTCKHTGGSPRPPCQYRASAGFRHVVIACENGLPVHFDESFFSL
What is the function of this protein?
Ribonuclease that cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) (PubMed:19114040, PubMed:33986151).  Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus (By similarity).  Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA (By similarity).  Angiogenin induces vascularization of normal and malignant tissues (By similarity).  Angiogenic activity is regulated by interaction with RNH1 in vivo (By similarity).
What are the official names of this protein?
Angiogenin, Angiogenin-1, Ribonuclease 5, RNase 5.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle lumen. Secreted. Nucleus, nucleolus. Note=Rapidly endocytosed by target cells and translocated to the nucleus where it accumulates in the nucleolus and binds to DNA (By similarity).
Protein: O4A47_HUMAN
Sequence: MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMYFFLAGLSFIDIIYSSSISPRLISGLFFGNNSISFQSCMAQLFIEHIFGGSEVFLLLVMAYDCYVAICKPLHYLVIMRQWVCVVLLVVSWVGGFLHSVFQLSIIYGLPFCGPNVIDHFFCDMYPLLKLVCTDTHAIGLLVVANGGLACTIVFLLLLISYGVILHSLKNLSQKGRQKALSTCSSHMTVVVFFFVPCIFMYARPARTFPIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKLWRRDLISSST
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 4A47, Olfactory receptor OR11-113.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.