PharMolix/UniProtQA huggingface dataset:
Protein: ACSA_YERPN
Sequence: MSQIHKHPIPAAIAEHALITPEKYQHYYQQSVQNPDEFWGEQGKIIDWIKPYKTVKNTSFDPGHVSIRWFEDGTLNLAANCLDRHLAERGDQTAIIWEGDDPNQSKTVTYKQLHHDVCQFANVLKSLGVKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPDAVAGRIIDSHSKLVITADEGIRAGRAIPLKKNVDEALKNPAITSIKNVVVFQRTGNASYWEDGRDVWWHDLIKEASADCPPEEMNAEDPLFILYTSGSTGKPKGVVHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGAITLMFEGVPNYPGVNRLSQVVDKHKVNILYTAPTAIRALMAEGDKAIEGTKRDSLRIMGSVGEPINPEAWEWYYNKIGNSKCPIVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNLGNPQEGVAEGNLVITDSWPGQARTLFGDHERFEQTYFSTFKGMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGVPHNIKGQAIYAYITLNHGEEPTPELYTEVRNWVRKEIGPLATPDILHWTDSLPKTRSGKIMRRILRKIATGDTSNLGDTSTLADPSVVEKLLEEKQSMQTPS
What is the function of this protein?
Enables the cell to use acetate during aerobic growth to generate energy via the TCA cycle, and biosynthetic compounds via the glyoxylate shunt.  Acetylates CheY, the response regulator involved in flagellar movement and chemotaxis.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: GBP2_MOUSE
Sequence: MASEIHMSEPMCLIENTEAQLVINQEALRILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKRTGFSLGSTVQSHTKGIWMWCVPHPKKAGQTLVLLDTEGLEDVEKGDNQNDCWIFALAVLLSSTFIYNSIGTINQQAMDQLHYVTELTDLIKSKSSPDQSGVDDSANFVGFFPTFVWTLRDFSLELEVNGKPVTSDEYLEHSLTLKKGADKKTKSFNEPRLCIRKFFPKRKCFIFDRPAQRKQLSKLETLREEELCGEFVEQVAEFTSYILSYSSVKTLCGGIIVNGPRLKSLVQTYVGAISNGSLPCMESAVLTLAQIENSAAVQKAITHYEEQMNQKIQMPTETLQELLDLHRPIESEAIEVFLKNSFKDVDQKFQTELGNLLVAKRDAFIKKNMDVSSARCSDLLEDIFGPLEEEVKLGTFSKPGGYYLFLQMRQELEKKYNQAPGKGLQAEAMLKNYFDSKADVVETLLQTDQSLTEAAKEVEEERTKAEAAEAANRELEKKQKEFELMMQQKEKSYQEHVKKLTEKMKDEQKQLLAEQENIIAAKLREQEKFLKEGFENESKKLIREIDTLKQNKSSGKCTIL
What is the function of this protein?
Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens (PubMed:18025219, PubMed:24739961, PubMed:24715728, PubMed:25774715, PubMed:25774716, PubMed:27693356, PubMed:30062052).  Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (By similarity).  Following infection, recruited to the pathogen-containing vacuoles or vacuole-escaped bacteria and acts as a positive regulator of inflammasome assembly by promoting the release of inflammasome ligands from bacteria (PubMed:24739961, PubMed:24715728, PubMed:25774715, PubMed:25774716).  Acts by promoting lysis of pathogen-containing vacuoles, releasing pathogens into the cytosol (PubMed:24739961, PubMed:24715728, PubMed:25774715, PubMed:25774716).  Following pathogen release in the cytosol, promotes recruitment of proteins that mediate bacterial cytolysis, such as Gm12250/Irgb10: this liberates ligands that are detected by inflammasomes, such as lipopolysaccharide (LPS) that activates the non-canonical CASP4/CASP11 inflammasome or double-stranded DNA (dsDNA) that activates the AIM2 inflammasome (PubMed:24739961, PubMed:24715728, PubMed:25774715, PubMed:25774716, PubMed:27693356, PubMed:30062052).  Confers protection to the protozoan pathogen Toxoplasma gondii (PubMed:18025219).  Independently of its GTPase activity, acts as an inhibitor of various viruses infectivity by inhibiting FURIN-mediated maturation of viral envelope proteins (By similarity).
What are the official names of this protein?
Guanylate-binding protein 2, GTP-binding protein 2, GBP-2, mGBP-2, mGBP2, Guanine nucleotide-binding protein 2, Interferon-induced guanylate-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane; Lipid-anchor. Cytoplasmic vesicle. Note=GBP2- GBP5 dimers localize to the Golgi apparatus.
Protein: APT_OCEIH
Sequence: MEFKNYIEIVEDWPKEGIKFKDITPLMADGKAFKSAVDEIVDYANTKEIDLVVGPEARGFIVGCPVSYALEVGFAPVRKEGKLPREVIKVDYGLEYGENVLTIHKDAIKPGQRVLITDDLLATGGTIEATIKLVEQLGGIVVGCAFLVELGYLDGKDKLEGYDVLTLMKY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_NEIMF
Sequence: MNPLISDFQTPQQRTPVIVALDFSNEKDTLGFVRNLDPTLCQIKIGKELFTATGRNLAESLINQGFKLFLDLKYHDIPHTVAQACKVAADMGVWMVDMHASGGRRMMEAAAEAVAGYGTKPLLIGVTVLTSMEQSDLAEIGLNTAPEEQVIRLAKLAQSSGLDGVVCSAQEAAPLRRELGQDFVLVTPGIRLDVAGNNDDQRRIMTPAEALAAGSTYLVMGRPVTQAADPVAVLREVNRVANLEAN
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RF1_ECO81
Sequence: MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYCLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADNP_RAT
Sequence: MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNSSAPSSSLSTFKDKNKNDGLKPKQADNVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVSLGTNAREECNIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRAKPLMLIAPKPQEKKSMGLPPRISSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSNVHLQQNNYGVKSVGQSYGVGQSVRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGAEQRPPAAARYSLQTANTSSLPPGQVKSPSVSQSQASRVLGQSSSKPPPAATGPPPSNHCATQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNAPVPPKPQPKVQEKADVPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPGLAPVKRTYEQMEFPLLKKRKLEDENDSPGCFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKASRVNASKTVDKKLNLGKEDDSFSDSFEHLEEESNGSGGPFDPVFEVEPKIPSDNAEEPVPKVIPEGALESEKLDQKEEEDGSKYETIHLTEERAKLMHDASDSEVDQDDVVEWKDGASPSESGPGSRQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATVQDDTEQLKWKNSSYGKVEGFWSKDQSQWENASENAERLPNPQIEWQNSTIDSEDGEQFDSMTDGVADPMHGSLTGVKLSSQQA
What is the function of this protein?
May be involved in transcriptional regulation.  May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.  Positively modulates WNT-beta-catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1.  May be required for neural induction and neuronal differentiation.  May be involved in erythroid differentiation.
What are the official names of this protein?
Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZAPA_MANSM
Sequence: MSSKTIELNFLGQVLRLNCPEEQHDSLREAAKLLDSRVTEMKDRTGILQVEKALAIVALNLSFELLQEQHKTHKTENVLQNQIEQLTRSLESISASTPTQQASYSID
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division (By similarity).
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid- cell.
Protein: HSLO_NOSP7
Sequence: MADQLIRATAAEGGIRAVGVITTRLTEEARQRHKLSYVATAALGRTMAAGLLMASSMKRSGSRVNVRVKGDGPLGGILVDAGLDGTVRGYVGNPSIELPPNAKGKLDVGGAVGGGYLYVVRDVGYGYPYSSTVELVSGEIGDDVAHYLVNSEQTPSALVLGVFVGAGGVTAAGGLLIQVLPKAARDEALVETLESRVAGLAGFTPLLQAGKNLTEIFSDLLGDMGLEIFSERQMLRFHCGCSFDRVLGALKILGEAELQDMIVKDNGAEATCDFCSNVYQASSDQLAQLIADLQAESTVSG
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELD_PORG3
Sequence: MNRSSFDLLSTVEYGGCSAKLDPAKLSELLHDIPLPVDSRIMVDVSTHDDAGVYRLNDDTALIVTTDFFPPVCSDPYTFGRIAAANALSDVYAMGGRPLLVLNLTMFPSEGIPVEVLADILRGGQQTIDESGAFTMGGHTIDDPIPKYGLAVTGIVHPEHLVTNAGVRAGQCLVLTKPLGIGVAMAAHRLGLIGSEVYEAAIGQMCLLNRAGAELMQKYGIRGATDITGFGLLGHAKELAEASDVCLHIDSRSVPVLPECLSLLRDGCIPGATFRNLRFVGDMLRADCPTEYKMLLADAQTSGGLLMAVDADRAEDLVADLHRTGLHPFAAIIGYATDAEDAAKLIVT
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: AROB_STAAB
Sequence: MKLQTTYPSNNYPIYVEHGAIKYIGTYLNQFDQSFLLIDEYVNQYFANKFDDIFSYENVHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGATGDFAGFVAATLLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYRPTAVIYDLDFLKTLPFEQILSGYAEVYKHALLNGESATQDIEQHFKDREILQSLNGMDKYIAKGIETKLDIVVADEKEQGVRKFLNLGHTFGHAVEYYHKIPHGHAVMVGIIYQFIVANALFDSKHDINHYIQYLLQLGYPLDMITDLDFETLYQYMLSDKKNDKQGVQMVLIRQFGDIVVQHVDQLTLQHACEQLKTYFK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1680_ARCFU
Sequence: MKKFMINCFVHLKEICYLSDMDILENMVKNLLKYESEVHKLLSTYESAGKSRIIRLDESYKELDGLSIEQDELFREALRCVENGLFRAAHVLAWAGFIDFLHSILALHIPQIKNKKEKWKISKKEDFREYPDFQIIEAAKDVGILNKSEMKTLKGLLSKRNECAHPSDYFPDLNETLGYISELLKRIKILQMRIKEK
What are the official names of this protein?
Uncharacterized protein AF_1680.
Protein: YM304_YEAST
Sequence: MIYGKMMGNTVLKNTGVFYQVIKPLKLHLLYDHSFSLFLKKQPNMGEISPFPYLLSYSYHVIVYLCVLCKVYILYSFVKDFSICLPFSYGSSLLYSLCSNLYIYIYAALPKSKIKL
What are the official names of this protein?
Putative uncharacterized membrane protein YMR304C-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YPLC2_STAAU
Sequence: MIKRVNKLVLGISLLFLVISITAGCDMGKEEEIKKSFEKTLSMYPIKNLEDLYDKEGYRDDQFDKNDKGTWIIGSEMATQNKGEALKVKGMVLYMNRNTRSAKGFYYVNAVKKDEDGRPQDNKIEYPVKMVDNKIIPTKDIKDGNIKKEIENFKFFAQYGTFKDLSKYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYDIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGENTFFTDSLHLEPSEDK
What are the official names of this protein?
Uncharacterized lipoprotein in plc 3'region, ORF CM06.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GLPE_YERPA
Sequence: MEQFEAISVEQAYLRWKEGKTALVDIRDPQSYEAGHAPGAFHLTNSSLHTFMQQTDFDQPVMVMCYHGNSSKGAAQYLLQQGFDVVYSIDGGFEAWARSYPQDITSESR
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_BART1
Sequence: MAAKEVKFGREARERLLRGVDILANAVKVTLGPKGRNVVIDKSFGAPRITKDGVSVAKEIELEDKFENMGAQMLREVASKTNDIAGDGTTTATVLGQAIVQEGVKAVAAGMNPMDLKRGIDAAVDEVVANLFKKAKKIQTSAEIAQVGTISANGAAEIGKMIADAMEKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNAEKMVADLDDPYILIHEKKLSNLQSLLPVLEAVVQSGKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTSGQVISEDVGIKLENVTLDMLGRAKKVNISKENTTIIDGAGQKAEITARVNQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKEKKDRVDDALNATRAAVEEGIVAGGGTALLRAASALTVKGGNPDQEAGINIVRRALQAPARQIATNAGEEAAIIVGKVLENNADTYGYNTATGEFGDLIALGIVDPVKVVRSALQNAASIASLLITTEAMVAEMPKKDTPMPPMPAGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLP7_PHONI
Sequence: QKKDRFLGLF
What are the official names of this protein?
Tachykinin-like peptide-VII, P.nigriventer tachykinin peptides VII, PnTkP-VII, U29-ctenitoxin-Pn1g, U29-CNTX-Pn1g.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPPH_XANC8
Sequence: MIDPDGFRPNVGIVLMREDGQVFWARRVRRDGWQFPQGGMNTDETPVEAMYRELREETGLLPEHVELLGATPGWLRYRLPSRAVRRNERQVCIGQKQVWFLLQFTGQESHLKLDHTDSPEFDHWRWVDFWYPVEHVVMFKRGVYARALRHLAPLAQTVAGPAAVGVMPQRALEAWLPGSSAAGHDRPRKRPRKRGGVLPVRINND
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: TRMD_MYCPN
Sequence: MKITVLTLFEQVVWPYLNASIMAQAQKAKLVEFEVINWRQYCKDKHQTVDDMAYGGGGGMVLKAEPILKALKACRTPQSKVVLLSPEGQQFSQPMAQALTQTEHLILICGHYEGFDYRLYKHVDQIISLGDFVLSGGELVALSVIDATVRLIKGVINDQSLIHESFNNYLLDFPAYTRPYDLDGDKVPEILLSGDHKKIEAYRKEQQLLRTAQYRPDLYKQYLAKKDEKNK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_BUCCC
Sequence: MKKKKEYRIAVLPGDGIGPEVMQEAYKILNVINKKFDFNIYTNEYDIGGIAIDKYGAPLPKKTLNGCIESHAILFGSIGGKEWTHLPADEQPERGGLLPLRKFFNLFVNLRPIKLHFSLKKLSPLKKEIIQDGFDILCVRELIGGIYFGLPKGKNTFDKKNISAFDTEIYSTKEIEKIADIAFQLSLKRKKKVFSIDKANVLESSMLWREVVIQVSKRYPNVELIHLYIDNAAMQLIKNPNQFDVILCSNLFGDILSDECAALTGSLGMLPSASLNESFFGLFEPAGGSAPDLKGKNIANPIAQILSLALLFKYSLQLEKISHLIELSVLKTLEKGYRTLDISNGKKYITTDQMGNYIAKTLSELIN
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U17L1_HUMAN
Sequence: MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes that may include cell proliferation, progression through the cell cycle, apoptosis, cell migration, and the cellular response to viral infection.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein 1, Deubiquitinating enzyme 17-like protein 1, Ubiquitin thioesterase 17-like protein 1, Ubiquitin-specific-processing protease 17-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum.
Protein: HSDL2_PONAB
Sequence: MLPNTGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCIVDVRDEQQINAAVEKAIKQFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPIWFKQHCAYTIAKYGMSMYVLGMAEEFKGEIAVNALWPKTAIHTAAMDMLGGPGIESQCRKVDIIADAAYSIFQKPKSFTGNFVIDESILKEEGIENFDVYAIKPGHPLQPDFFLDEYPEAVSKKMESTGAVPEFKEEKPQPQPKPRSGAVEETFRIVKDSLSDDVVKATQAVYLFELSGEDGGTWFLDLKSKGGNVGYGEPSDQADVVMSMTTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLEKLMNQMNARL
What is the function of this protein?
Has apparently no steroid dehydrogenase activity.
What are the official names of this protein?
Hydroxysteroid dehydrogenase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: 3DHQ_ASPCL
Sequence: MGKSILLINGPNLNLLGTREPHIYGSTTLPDIVASSKAHAESLGATLEAFQSNHEGAIVDRIQEARGNVDGIVINPGAFTHTSVAIRDALLAVNIPFIELHVSNVHAREPWRHHSYFSDKAAGIIVGLGAYGYKVAVEHVALNFKERASL
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase, cDHQase, 3-dehydroquinate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RS6_BACAC
Sequence: MRKYEIMYIIRPGVEEEAQKALVERFAGVLTNNGAEIINTKEWGKRRLAYEINDLREGFYMILNVNANAEAINEFDRLAKINEDILRHIVVKEEEK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: FLGB_ECOL6
Sequence: MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDIDFASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDMDRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB, Putative proximal rod protein.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: G137A_BOVIN
Sequence: MESNLSGLVPAAGLVPALPPAVTLGLTAAYTTLYALLFFSVYAQLWLVLLYGHKRLSYQTVFLALCLLWAALRTTLFSFYFRDTPRANHLGPLPFWLLYCCPVCLQFFTLTLMNLYFAQVVFKAKAKRRPEMSRGLLAVRGAFVGASLLFLLVNVLCAMLSRRRRAQPWALLLVRVLVSDSLFVICALSLAACLCLVARRAPSTSIYLEAKGTSVCQAAAMGGAMVLLYASRACYNLAALALAPRSRLDAFDYDWYNVSDQADLVNDLGNKGYLVFGLILFVWELLPTTLLVGFFRVHRPPQDLSTSRILNGQVFGSRSYFFDRAHCEDEGCSWEHSRGESTSMSGSLGSSSWYGTIGREPGWCGGSQTRTTPLLFSQVLGPGGHHHSLYSTPQT
What is the function of this protein?
May activate Wnt/beta-catenin signaling to modulate epithelial cell function.
What are the official names of this protein?
Integral membrane protein GPR137.
What is the protein family that this protein belongs to?
Belongs to the GPR137 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: FTHS_SHESR
Sequence: MLTDMDISRRADLKDIAALGAEFGLLPDEMQLFGKTKAKVDLRVQQRLAEQQGKLIIVTAVTPTPHGEGKTVTTIGLTQSLKALGNKVCACIRQPSMGPVFGVKGGAAGGGYAQVVPMQELNLHLTGDIHAVSSAHNLGAAAIASRLYHETRLGKAEFELQSGQNYLDIAPNGIRWHRVVDHNDRCLREIEVGLGENNGPAYTSGFDITAASELMAILALSRNLADMRARIGKLVLAVNRQGAAISAEDLGVAGAMTALMADAVKPTLMQTLNGAPCLIHAGPFANIAHGNSSVIADDIALKLADFVVTEGGFGSDMGFEKFCNIKARQSGLAPSTAVLVTTLKALKANSGLTSDADINAPDQARLEAGFANLNWHINNVARYGIPVVVAINRFATDTDAELNWLIEAVSGTAAFGCELSETFSQGEAGALALAQTVMRACEQPSEFTLLYPDDMALEAKLSTLAEVGYGAAGVSLSEAAKLQLQELSALGYAHLPVCMAKTPLSISHDPQLKGVPQGFIVPVRELVLNAGAGFITALVGNVMTMPGLGLVPGYLKIDIGADGEITGLG
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RL25_PHODP
Sequence: MKFEAVVRTDLGKGASRRLRHANQFPAIVYGGEEVPVAIVLDHDSVINQMDKPAFYEVITLVIDGKEVQVKPQDIQRHPYKPKVNHMDFKRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: FTSK_RICCN
Sequence: MLYYINKILSNNKVQAVILGIIGLGIVIVLTSYNIDDPSFNSVTTEYHSNLVGIFGSYLSDCLYQFFGLAAFIIPLACFVWGRNCWYGRYRGSFIRMFVMLLALVSSSTLLSKIKLEFIPANAGGAIGIIASNFFERFTNQLYLLLIFFTFIILVVLFEIKFTSLSNFIIKLGNFLIYRIQSFLHNVFSRLSSIRLFPTKNNDKINITSSYQKPVSEKVKFPEEARSVPANPIKFFSKPVSPKISQSEIAELPPISLLRDPEKHHVKGASSLELKQKAEELLTVLNDFGVKGQIININQGPVVTQYEFEPAAGTKTSRVVGLSDDIARSLSALSTRIAVIPGKNVLGIELPNKQREFFCLKELIETPEYQDKSTLLPLVLGKDLAGKPLVADLAKMPHLLVAGTTGSGKSVGINVMIVSLLYRYTPEECRFIMIDPKMLELSAYDGIPHLLTPVVTEPSKAVVALKWAVKEMENRYRMMSNIGVKNIAGYNAKILEAVKENRIIERSIQTGFDPETGKPIYETVTMKMEKLPYIVVIVDEMADLMLVAGKDIEMLIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPSRISFKVTSKIDSRTILGEQGSEQLLGMGDMLFMGSTSKISRVHGPFVNEAEIEQITEYLKESGTPEYISAVTEQPEEDDSGIDIGDGTSDEVLYKKAVQIVRDERKSSISYIQRSLRIGYNKAANLVEKMEKEGIVSPPNHTGKREILLPER
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.