PharMolix/UniProtQA huggingface dataset:
Protein: PUR2_STAAM
Sequence: MNVLVIGAGGREHALAYKLNQSNLVKQEFVIPGNEAMTPIAEVHTEISESNHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEGSKLFAKKIMKKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTIEAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHDEGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKDGPKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGYPDAYEKGHKVSGFDLNENYFVSGLKKQGDTFVTSGGRVILAIGKGDNVQDAQRDAYEKVSQIQSDHLFYRHDIANKALQLK
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: CCTO_TALIS
Sequence: MPLYSQIRQSEDAFSEPTYAATNELINDNENACPHCRQERSESWFLKGGRSIVYVSLTFFVVSIGLNFILAILLYSKFHASSFQTEWSAAVADTDCVRRLVAYTPALDSIEYFATNLRDAYRSNDQYLGPPTKEREQMWQDLWLHEAIMVETWAMPLLNRINLDPYEKVEGELGDGYNALLQVHHQLGCLDILRQYTWLLSGKYTTDGIPVPIFLQKPPEENRRHVDQCIEELRMGLMCHGDMTPLLITKKRDGASGFKADMNTHYMCRNFTKLQEWTMSHGVEHWELGDGRGPHEHGRR
What is the function of this protein?
Part of the gene cluster that mediates the biosynthesis of the mycotoxin cyclochlorotine, a hepatotoxic and carcinogenic cyclic chlorinated pentapeptide (PubMed:26954535).  Cyclochlorotine is formed by the nonproteinogenic amino acids L-2-aminobutyrate (2Abu), L-beta-phenylalanine (beta-Phe), the unique L-cis-3,4-dichloroproline Pro(Cl(2)) and two L-serines (Ser) (PubMed:26954535).  The condensation of the 5 building blocks is performed by the cyclochlorotine synthetase cctN, a nonribosomal peptide synthetase (PubMed:26954535).  The assembled linear pentapeptide is then assumed to be released through cyclization by the terminal condensation-like domain of cctN (PubMed:26954535).  Incorporation of the alternative substrates allo-threonine or alanine by the domains A3 or A1 respectively may lead to the production of the variants hydroxy-cyclochlorotine and deoxy-cyclochlorotine, respectively (PubMed:26954535).  CctP probably acts as a phenylalanine aminomutase and provides the uncommon building block beta-Phe (PubMed:26954535).  Furthermore, 2Abu can be synthesized from threonine by one of the threonine dehydratases and transaminases localized outside of the cluster (PubMed:26954535).  The biosynthesis of the unusual dichloroproline moiety remains elusive since the actual halogenase still awaits to be detected, with the possibility that proline halogenation is accomplished by a so far unknown type of halogenase (PubMed:26954535).  Finally, the cluster encoded transporters cctQ and cctS are most likely responsible for cyclochlorotine secretion and thereby may contribute to intrinsic resistance (PubMed:26954535).  The functions of the remaining proteins encoded by the cluster (cctM, cctO, cctR and cctG) have not been identified yet (PubMed:26954535).
What are the official names of this protein?
Cyclochlorotine biosynthesis protein O.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PRP28_ASPTN
Sequence: MPGPPATAPPPEPIERPPTPPPPPPEDSAAPPPPPDMSAPPPPPQDELPPAPEPKKKKLGWGSKRPAAAPLSVEELVRKKREADAAAAKPKFLSKKEREKIALEKRAKEVEQSRRKTSTNGASDTASVRSESATPNGVDRTASIPTGPRAMRTSEAPPPPRPRHDSSSNGNGNSNSNSNSNGTVDEDEAAAQAALVKQRYMGAEMTSSFSAKKKRKRTTDRKFNFEWNAEEDTSRDYNPLYAQRHEANFFGRGRLAGFGDDVADGVARKYAAALEDRDREAGSVRAREILEMERRRREESTRNQLDKHWSEKKLEHMRERDWRIFKEDFNIATKGGSVPNPMRSWAESGLPSRLLDLVHRVGYKDPTPIQRAAIPIAMQSRDLIGVAVTGSGKTAAFLLPLLVYIAELPRIDEFEWRKNDGPYAIVLAPTRELAQQIEIEAKKFTIPLGFTVVSIVGGHSLEEQAYSLRNGAEIIIATPGRLVDCIERRLLVLSQCCYVIMDEADRMIDLGFEEPVNKILDALPVSNEKPDSDAAENAAAMSQLHHAGGGRDTRYRQTMMYTATMPTAVERIARKYLRRPAIVTIGSAGEAVDTVEQRVELIAGEDKRKKRLGDILSSGEFRPPIIVFVNIKRNCDAIAREIKQWGFSSVTLHGSKTQEQREAALASVRNGSTDVLVATDLAGRGIDVPDVSLVVNFNMATSIESYTHRIGRTGRAGKSGVAITFLGNEDADVMYDLKQMLIKSPISRVPDELRKHEAAQQKPTRGFSKKNDESSAFGGKGGW
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase prp28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CHI1_METRA
Sequence: MPSLFAQSLAIIATLQATLGLATPVSAPDTVTGKHAGGYVNAVYFTNWGIYGRNYQPADLPASQISHVLYSFLNLSNNGTVYSGDSWADIDKHYPNDSWNDVGNNVYGCVKQLYLLKKANRNMKTMLSIGGWTWSTNFPAAASTAATRSNFAKSAVTIMKDWGFDGIDVDWEYPADDAQAANMVLLLQAVRDELDAYAAKFAQGYHFQLSIAAPAGPANYNKLHLGDLGKVLDYINLMAYDFSGSWSNSSAHNANLYANPGNLNATPFNTDDAVNDYIKGGVPASKIVLGMPIYGKSFQKTNGIGKPFSGVGDGSWENGIWDYKVLPKAGATVIYDDVAKGYYSYDNRTQELISYDTPDITKEKVTYLKSKGLGGSMFWEASADRQGPDSLIGTSSNKLGGPDTTENLLNYPDSKYDNMRKQMA
What is the function of this protein?
Secreted chitinase involved in the degradation of chitin, a component of the cell walls of fungi and exoskeletal elements of some animals (including worms and arthropods).  Participates in the infection process and directly acts in the penetration process of the host cuticle (By similarity).
What are the official names of this protein?
Endochitinase 1, Chitinase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family. Chitinase class V subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG_MESH7
Sequence: MARKFELKDYRNIGIMAHIDAGKTTTTERILFHTGKIHKIGETHDGVSQMDWMEQEKERGITITSAATTAFWKGKRINIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATNYSVPRIVYVNKMDKAGANFEASIESVRTKLNGNAVAIQLNIGAEADFSGLIDLVEMKAYNYDGQKEEIEYEIPIPEDLFEKASQMRLALAEAVADYDEEIFNNLLEEKEILPEQLKAAIRAATITGNFFPVVCGSSFKNKGVKKMIDAVIDYLPSPVDVPPIKAFRDEEEITIEASDDQEFSALAFKIMNDPFVGSLTFFRVYSGVLKKGTYIINSTKGKKERVGRILAMHANSREEIDEVRTGDIGAFVGLKDTTTGDSLISEKAKTFVLERMNFPEPVISQSLEPFSKAEIEKLATALQKLANEDPTFKTWTDIETGQTIIAGMGELHLDIIVDRLKREFNVQARVGKPQVSYRETITKSAEVEGKYIKQSGGRGQYGHVWIKFEPNPEEGFDFIDKIVGGKIPKEYIKSIQKGLEEKMQAGILAGYPLINLRATLFDGSFHEVDSSEMAFKIAASKALSRARDAVGTVLLEPIMDVSVFAPSEYAGDVMGDLSRRRGLVREQETRSDGANVIRGHVPLAEMFGYSTQLRSMTSGRGTYQMQFNHYEIVPKNISDVIVKQRAIKEDD
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYBA1_BIFL2
Sequence: MNVTITSPFWKRRRDQIVESVIPYQWGVMNDEIDTTVPDDPAGNQLADSKSHAVANLKVAAGELDDEFHGMVFQDSDVYKWLEEAAYALAYHPDPELKALCDRTVDLIARAQQSDGYLDTPYQIKSGVWADRPRFSLIQQSHEMYVMGHYIEAAVAYHQVTGNEQALEVAKKMADCLDANFGPEEGKIHGADGHPEIELALAKLYEETGEKRYLTLSQYLIDVRGQDPQFYAKQLKAMNGDNIFHDLGFYKPTYFQAAEPVRDQQTADGHAVRVGYLCTGVAHVGRLLGDQGLIDTAKRFWKNIVTRRMYVTGAIGSTHVGESFTYDYDLPNDTMYGETCASVAMSMFAQQMLDLEPKGEYADVLEKELFNGSIAGISLDGKQYYYVNALETTPDGLDNPDRHHVLSHRVDWFGCACCPANIARLIASVDRYIYTERDGGKTVLSHQFIANTAEFASGLTVEQRSNFPWDGHVEYTVSLPASATDSSVRFGLRIPGWSRGSYTLTVNGKPAVGSLEDGFVYLVVNAGDTLEIALELDMSVKFVRANSRVRSDAGQVAVMRGPLVYCAEQVDNPGDLWNYRLADGVTGADAAVAFQADLLGGVDTVDLPAVREHADEDDAPLYVDADEPRAGEPATLRLVPYYSWANREIGEMRVFQRR
What is the function of this protein?
Beta-L-arabinofuranosidase that removes the beta-L-arabinofuranose residue from the non-reducing end of various substrates, including beta-L-arabinofuranosyl-hydroxyproline (Ara-Hyp), Ara-beta-1,2-Ara-beta-Hyp (Ara(2)-Hyp), Ara-beta-1,2-Ara-beta-1,2-Ara-beta-Hyp (Ara(3)-Hyp), and beta-L-arabinofuranosyl-(1->2)-1-O-methyl-beta-L-arabinofuranose.  In the presence of 1-alkanols, shows transglycosylation activity, retaining the anomeric configuration of the arabinofuranose residue.
What are the official names of this protein?
Non-reducing end beta-L-arabinofuranosidase, Beta-L-arabinofuranosidase, Beta-AFase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 127 family.
Protein: E4PD_ECO57
Sequence: MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMATVAFR
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERA_MYCTU
Sequence: MSLPVVLIADKLAPSTVAALGDQVEVRWVDGPDRDKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVNAPTSNIHSAAEHALALLLAASRQIPAADASLREHTWKRSSFSGTEIFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFISVHLPKTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHVRAAGLDVFATEPCTDSPLFELAQVVVTPHLGASTAEAQDRAGTDVAESVRLALAGEFVPDAVNVGGGVVNEEVAPWLDLVRKLGVLAGVLSDELPVSLSVQVRGELAAEEVEVLRLSALRGLFSAVIEDAVTFVNAPALAAERGVTAEICKASESPNHRSVVDVRAVGADGSVVTVSGTLYGPQLSQKIVQINGRHFDLRAQGINLIIHYVDRPGALGKIGTLLGTAGVNIQAAQLSEDAEGPGATILLRLDQDVPDDVRTAIAAAVDAYKLEVVDLS
What is the function of this protein?
Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway.  Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
What are the official names of this protein?
D-3-phosphoglycerate dehydrogenase, PGDH, 2-oxoglutarate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
Protein: NDOR1_GIBZE
Sequence: MAVQDRSVLVLYGSETGNAQDMAEELGRICQRLHFKSRVEELDVVDLNALLQPKFVIFVISTTGQGDMPHNSLLFWKRLLRKKLPPGCLASVNYTTFGLGDSTYLKFNWAARKLNRRLDQLGAATFIDPYEADEQFPDGLDGSFVRWTGRLYNHFLEHHPAPSGLEPIPDDVILPPKWSLETTIQNSTETNGHVPPSLENIPSSTLLPIPDGWTATLVGNGRLTPEKHWQDVRLISFDVPRRDGVKLACVPGDCLTIYPKNFPQDVQRLITLMEWEDIADKPLDLSQCESLPTNLFTDSKSTLRELLLNNIDFTAIPRRSFLKNMSYFSTNPDHKERLLEFTMAEYLDEYFDYATRSRRSILEVLEEFSSVKLPAERLFDIFPLIRGRDFSIANGGVHQSHPTDENKTRIELLVALVKYRTVLRKPREGLCSRYLDNIPMNSTLTVTRKPVLSPIHGAQNAQRPLVAIATGTGLAPIRALLHERLTQPSPGPMYLFFGNRNREADYFFQQEFDALVTEGQLNVFLAFSRDQRNKIYVQDRLLEEAKRIEEVIFDNGIFCVCGGSTKMADAAKKAVFEPFSEDVKDVEERKKMLASLTWWQEIW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: PP242_ARATH
Sequence: MKCLKDGFLHHIRSIKSGSTLTAVSSNQLVNLYSKSGLLREARNVFDEMLERNVYSWNAVIAAYVKFNNVKEARELFESDNCERDLITYNTLLSGFAKTDGCESEAIEMFGEMHRKEKDDIWIDDFTVTTMVKLSAKLTNVFYGEQLHGVLVKTGNDGTKFAVSSLIHMYSKCGKFKEVCNIFNGSCVEFVDSVARNAMIAAYCREGDIDKALSVFWRNPELNDTISWNTLIAGYAQNGYEEEALKMAVSMEENGLKWDEHSFGAVLNVLSSLKSLKIGKEVHARVLKNGSYSNKFVSSGIVDVYCKCGNMKYAESAHLLYGFGNLYSASSMIVGYSSQGKMVEAKRLFDSLSEKNLVVWTAMFLGYLNLRQPDSVLELARAFIANETNTPDSLVMVSVLGACSLQAYMEPGKEIHGHSLRTGILMDKKLVTAFVDMYSKCGNVEYAERIFDSSFERDTVMYNAMIAGCAHHGHEAKSFQHFEDMTEGGFKPDEITFMALLSACRHRGLVLEGEKYFKSMIEAYNISPETGHYTCMIDLYGKAYRLDKAIELMEGIDQVEKDAVILGAFLNACSWNKNTELVKEVEEKLLVIEGSNGSRYIQIANAYASSGRWDEMQRIRHQMRGKELEIFSGCSWANIDKQFHMFTSSDISHYETEAIYAMLHFVTKDLSEIDEIMI
What are the official names of this protein?
Putative pentatricopeptide repeat-containing protein At3g18840.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: ARGR_GEOKA
Sequence: MNKGQRHIKIREIIMNHDIETQDELVDRLREAGFNVTQATVSRDIKEMQLVKVPMANGRYKYSLPSDQRFNPLQKLKRALVDVFVKLDGTGNLLVLRTLPGNAHAVGVLLDNLDWNEIVGTICGDDTCLIICRTPKDAEKVSDQLLSML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT02_YEAST
Sequence: MGNFRFPIKTKLPPGFINARILRDNFKRQQFKENEILVKSLKFIARNMNLPTKLRLEAQLKLNALPNYMRSTQIKNRCVDSGHARFVLSDFRLCRYQFRENALKGNLPGVKKGIW
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
37S ribosomal protein MRP2, mitochondrial, Mitochondrial small ribosomal subunit protein uS14m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: Y950_VIBA3
Sequence: MPIISKYTDDQVEKILAEVGAVLTKHKASPELSLMIAGNIATNVLNQNVAASQRKGIAEKFAEALISSLEDKKSH
What are the official names of this protein?
UPF0352 protein VS_0950.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: DAPD_PSEAE
Sequence: MSQSLFSLAFGVGTQNRQEAWLEVFYALPLLKPSSEIVAAVAPILGYAAGNQALTFTSQQAYQLADALKGIDAAQSALLSRLAESQKPLVATLLAEDAAPSSTAEAYLKLHLLSHRLVKPHAVNLSGIFPLLPNVAWTNIGAVDLAELAELQLEARLKGKLLEVFSVDKFPKMTDYVVPAGVRIADTARVRLGAYIGEGTTVMHEGFVNFNAGTEGPGMIEGRVSAGVFVGKGSDLGGGCSTMGTLSGGGNIVISVGEGCLIGANAGIGIPLGDRNIVEAGLYITAGTKVALLDEQNALVKVVKARDLAGQPDLLFRRNSQNGAVECKTNKTAIELNEALHAHN
What is the function of this protein?
Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA (By similarity).  Displays succinyl transferase activity with L-2-aminopimelate and succinyl-CoA as substrates (PubMed:22359568).
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR9_MOUSE
Sequence: MDSRELALASLMCDTGGPGELSVGHQQRRTKKWSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGTWYRRHGQPIDPDTLTLLWSVTVSIFAIGGLVGTLMVKMIGKFLGRKSTLLVNNGFAISAALLMACSLRAGTFEMLIVGRFIMGVDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLGRESTWPYLFGVIIVPALVQLASLPFLPESPRYLLFEKHDEAGAMKAFQTFLGKADVSQELEEALAESRVQRNLRLVSVLELLRAPFVRWQVITVIITMASYQLCGLNAIWFYTNSIFGKAGIPQDKIPYITLSTGGIETLAAIFSGLVIERLGRRPLLIGGFGLMALFFGTLTATLTLQDQAPWVPYLSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFMIAGTVNWLSNFAVGLLFPFIQKSLDSYCFLVFATICIAGATYFYFVLPETKNRTHAEISQAFAKRNKAQPPEVKADSAMTEEKANSQTEPDSSSTLDSYGQNKIV
What is the function of this protein?
High-capacity urate transporter, which may play a role in the urate reabsorption by proximal tubules.  May have a residual high-affinity, low-capacity glucose and fructose transporter activity.  Transports urate at rates 45- to 60-fold faster than glucose.  Does not transport galactose.  May mediate small uptake of adenine but not of other nucleobases.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 9, Glucose transporter type 9, GLUT-9, Urate transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: CH601_RHIEC
Sequence: MAAKEIKFGRTAREKMLRGVDILADAVKVTLGPKGRNVIIDKSFGAPRITKDGVSVAKEIELEDKFENMGAQMVREVASKTNDIAGDGTTTATVLAQAIVREGAKAVAAGMNPMDLKRGIDLAVAEVVKDLQAKAKKINTSEEVAQVGTISANGERQVGLDIAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNPEKMIADLEDVFILLHEKKLSNLQSMLPVLEAVVQTGKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGTVISEDLGIKLESVTLDMLGRAKKVSISKENTTIVDGSGAKSDIEGRVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGSTEVEVKEKKDRIDDALNATRAAVQEGIVPGGGVALLRSSVKISAKGVNDDQEAGINIVRRALQAPARQIAENAGDEASIVVGKILDKDQDNYGYNAQTGEYGDMIGMGIIDPVKVVRTALQDAASVASLLITTEAMIAELPKKDAPAMPGGMGGMGGMDMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_POLSJ
Sequence: MTRTASAPRSVGSARPLKAIYDVPAPAKLNLFLHITGRRADGYHLLQSAFMLIDWCDTLHFELRTDGQISRADLSDPGSPGCGAAEPLPAEDLAVRAARALQAACGTSLGVHIGLEKRIPSQAGMGGGSSDAASCLLALQRLWGVTLPATELRALALSLGADVPFFLSGGHAWVEGIGEKITPIALPAARFVVVKPSAGLSTPAIFSAPELKRDTETATIQGFAANAEGQVFGFGRNDLQPVAQALCPPIGQSLDWLSAQHLQGRMTGSGSAVFALLPHDVDLSDVPGTPGDWKIRKCSNLQAHPLAGW
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ARGB_SHISS
Sequence: MMNPLIIKLGGVLLDSEEALERLFSTLVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF1A_XENLA
Sequence: MSKATKRKHVVKEVLGDYVQPTEHQSIVKVLGSPGNNLHEVETAEGERFLASMPTKFRKNIWIKRGDFLIVDPIVEGEKVKAEIAFILYKDHQRLLQKEGLWPEGFTQDKTGLVAKEKESSGIQSTEAQAKPQGEDSETDDDSGLFVNTNHVHYEDSEEESESEEDEEN
What is the function of this protein?
May play a role into cellular response to oxidative stress.  May decrease cell proliferation (By similarity).
What are the official names of this protein?
Probable RNA-binding protein EIF1AD, Eukaryotic translation initiation factor 1A domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the EIF1AD family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HPRT_METIM
Sequence: MKLEESLKKCPVIKRGEYNYFVHPITDGIPLVEPSLLREVACRILKIVDFSEVDKIVTAEAMGIHLATTLSLYTDIPFVIIRKRSYGLEGEIPVFQKTGYSKGQLYVNGIKEGDKVVIVDDVISTGGTMIAIIEALKRAGAEIKDIVCVIERGKGREIVEKKTGYKIKTLVKIDVVDGKVVIK
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACBD5_CHICK
Sequence: MAETGSVHATRFEAAVKVIQSLPKNGSFQPTNEMMLKFYSFYKQATQGPCNIPRPGFWDPIGRYKWDAWSALGDMSKEEAMIAYVEEMKKILESMPMTDKVEELLQVIGPFYEIVEDKKNRGSGLTSDLSNVMNSTPNIKAVNGKAESSDSGAESEEEGLREEEEKELQQNVKDCKSPKTESLAAKDLENSVANDCYKDSFIPDMQNGIQTKSALNGLNVEEEIKKTEPSLEIANNCDHRGANEENTEEVSGTQHLTSDSDSEVYCDSMEQLGLEEPLEIITSAKGSLKRSSHFLDVDHRLQLENTDLPRHACTTAGNLQLGTAVDGAVQEKGEVKCGGEDGKASNGAPHKEKKDGEKADFYGVRRGRGHRLHPVGDGSQGGQMGNGGDGERWGSDRGPRGSLNEQIAVVLMRLQEDMQNVLQRLHMLEAVTASQARSATLQSNYQPASSVKKPSWWPFEISPGVLAFAIVWPFIAQWLVHVYLQRKRRKLN
What is the function of this protein?
Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy.  Binds medium- and long-chain acyl-CoA esters (By similarity).
What are the official names of this protein?
Acyl-CoA-binding domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the ATG37 family.
What are the subcellular locations of this protein?
Peroxisome membrane; Single-pass membrane protein.
Protein: PERX_WHEAT
Sequence: ALRGFGVIDSIKTQIEAICNQTVSCADILTVAARDSVVALGGPSWTVPLGRRDSIDANEAEANSDLPGFNSSRSELEAAF
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
Protein: HIS4_CORDI
Sequence: MTFTLLPAVDVVDGQAVRLDQGEAGTEKSYGSPIAAALKWQEQGASWLHFVDLDAAFNRGSNHELMAEVVKNLDINVELTGGIRDDASLKRALATGARRVNIGTAALEKPEWIEKVLGEYGDAIAVDIAVRNIDGQWRTRGNGWVSDGGDLWEVLERLDSQGCTRFVVTDVSKDGTLSGPNIDLLRDVSAATDAKVVASGGISTLEDVLELARYEDEGIDSAIIGKALYEGRFTLKEALAAL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECA_DIOVO
Sequence: ADTIVAVELDSYPNTDIGDPNYPHISIADENSLHFSFHKFSQNPKDLIL
What is the function of this protein?
D-mannose/D-glucose-binding lectin.
What are the official names of this protein?
Lectin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.