PharMolix/UniProtQA huggingface dataset:
Protein: RL24E_SULIA
Sequence: MPTTRQCSFCGHEIPPGTGLMYVRNDGTMLWFCSSKCRKSMLKYHRDPKKYKWTTRYMKVR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: PGK_STAA9
Sequence: MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHASNVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSNDAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKAINNK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYDGF_HUMAN
Sequence: MAAPSGGWNGVGASLWAALLLGAVALRPAEAVSEPTTVAFDVRPGGVVHSFSHNVGPGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRTEL
What is the function of this protein?
Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI).  Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway.  Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity).  Involved in endothelial cell proliferation and angiogenesis (PubMed:25581518).
What are the official names of this protein?
Myeloid-derived growth factor, MYDGF.
What is the protein family that this protein belongs to?
Belongs to the MYDGF family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus. Note=The C-terminal RTEL motif may provide retention in the endoplasmic reticulum.
Protein: GLMM_STRT2
Sequence: MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETGRPKVFVARDTRISGEMLESALVAGLLSVGIEVYKLGVLATPGVSYLVRTENASAGVMISASHNPALDNGIKFFGGDGFKLDDAREAEIEALLDAAEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGLDLGGMKVALDAANGAAAVSARNIFLDLNAEIAVIGDQPDGLNINAGVGSTHPEQLQALVRESGSAIGLAFDGDSDRLIAVDENGDIVDGDKVMYIIGKYLSQKGELAKNTIVTTVMSNLGFHKALDREGINKAVTAVGDRYVVEEMRKNGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLTKVMVETGKSLSELAAEVTIYPQKLVNIRVENSMKDKAMDVPAIAAIIEKMEAEMAGNGRILVRPSGTEPLLRVMAEAPTDDEVNYYVDTIADVVRAEIGLD
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RL15_PEDPA
Sequence: MKLNELMPSEGSRTNRKRIGRGTSSGTGKTAGRGQKGQKARGKVRLGFEGGQMPLYRRIPKRGFTNINRKEFAIVNLDALNVFDEGAEVTPESLLKAGIISKQLSGVKVLGNGEITKKLTVKANKFSESAVKAIEAAGGKTEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YHHN_SHIFL
Sequence: MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQAPMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSFFWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALSAFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL
What are the official names of this protein?
Uncharacterized membrane protein YhhN.
What is the protein family that this protein belongs to?
Belongs to the TMEM86 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROC_STAA1
Sequence: MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYGRGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISEEERENMKRTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLQQLDIDIYSRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDSIAQAMRDKIDEAKNEGDSIGGVVQVVVENMPVGVGSYVHYDRKLDGKIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEILYNSEIGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKATIERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLQQQIADRRQLNVEF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TM202_HUMAN
Sequence: MERREHLTLTFHSPEVPKIKGNRKYQRPTVPAKKHPSASMSCQRQQQLMDQAHIYIRTLCGSLCSFSLLMLIAMSPLNWVQFLVIKNGLELYAGLWTLCNHELCWSHTPKPPYYLQYSRAFFLISVFTILTGLGWLFSSWILNRGSMTTNLDLKVSMLSFISATCLLLCLNLFVAQVHWHTRDAMESDLLWTYYLNWCSDIFYMFAGIISLLNYLTSRSPACDENVTVIPTERSRLGVGPVTTVSPAKDEGPRSEMESLSVREKNLPKSGLWW
What are the official names of this protein?
Transmembrane protein 202.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RLMG_SHIBS
Sequence: MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLGPTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRSEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_BACP2
Sequence: MITFQLEQGEKLFIPFMTAGDPSEEITIDLALSLQAAGAHAIELGVPYSDPLADGPVIQRASKRALNHGMNIVKAIELAGKMKKNGVKIPVILFTYYNPVLQLDTEYFFALLRKNHISGLLTPDLPFEESSELQKNCQSYDISYISLVAPTSKERLVNIVEQAEGFVYCVSSLGVTGVRQTFDESITDFIQQVKQLSHIPVAVGFGISTREQVDSMNKLSDGVVVGSALVKKIEELHDQLLASDTRQDALREFETYAKTFSPLYSFK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CALM_STYLE
Sequence: MADNLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLSLMARKMKDTDTEEELVEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGHINYEEFVRMMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: SQUT_ECOLI
Sequence: MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSVLTDFKVNAAKALSPYASAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVDSVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEPVVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLCASQRLNDHINMPWVILSSGVDEKLFPRAVRVAMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPKLQQLGDIVDEMMAKRR
What is the function of this protein?
Cleaves 6-deoxy-6-sulfo-D-fructose 1-phosphate (SFP) to form dihydroxyacetone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
What are the official names of this protein?
Sulfofructosephosphate aldolase, SFP aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: PSB_STRSW
Sequence: MEANTRSTGRLPAAFLTPGSSSFMDFLSDHQPELLPGKRQLPPTQGVIEAPHGTTIVAVTFPGGVVLAGDRRATMGNMIAQRDIEKVFPADEYSAVGIAGTAGLAVEMVKLFQLELEHFEKVEGAQLSLEGKANRLSTMIRSNLGMAMQGLAVVPLFAGYDVDRNRGRIFSYDVTGGRSEESGYAATGSGSIFARGAMKKLFRADLSEADATTLVVQALYDAADDDSATGGPDVARRIYPIVTVITEDGFRRLTDEESSEIARSILERRLEQPDGPRAALL
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LV223_HUMAN
Sequence: MAWALLLLTLLTQDTGSWAQSALTQPASVSGSPGQSITISCTGTSSDVGSYNLVSWYQQHPGKAPKLMIYEGSKRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCCSYA
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 2-23, Ig lambda chain V-II region NEI.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: FKBX_PSEFL
Sequence: MTDQVLAEQRIGQNTEVTLHFALRLENGDTVDSTFDKAPATFKVGDGNLLPGFEAALFGFKAGDKRTLQILPENAFGQPNPQNVQIIPRSQFQNMDLSEGLLVIFNDAANTELPGVVKAFDDAQVTIDFNHPLAGKTLTFDVEIIDVKAL
What is the function of this protein?
PPIases accelerate the folding of proteins.
What are the official names of this protein?
Probable FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: SHU2_YEAS1
Sequence: MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLYYMFPRELFIRAISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGAPPILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDPHSLSKQWYFKFDKICCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLHINIVE
What is the function of this protein?
Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase.  Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity).
What are the official names of this protein?
Suppressor of hydroxyurea sensitivity protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHU2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AACUI_ASPA1
Sequence: MSLPIPPRPADNSTSHSLCLTICGYRRPGMSEFDYRQHMTQVSAPMTADLMVKYGVKRWTMIHNTTESRALMDQLIDPQMANIADFDCFSQMVLHDLADYKRLKEDPWYREHLVGDHEKFADTRRSMMTIGWVTEIVRDGQVV
What is the function of this protein?
Decarboxylase; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D (PubMed:30996871, PubMed:33891392).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase AacuL (Probable).  The atrochrysone carboxyl ACP thioesterase AacuM then breaks the thioester bond and releases the atrochrysone carboxylic acid from AacuL (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase AacuI, and oxidized by the anthrone oxygenase AacuG to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by a yet unidentified oxidoreductase (Probable).  A-ring reduction by the short chain dehydrogenase AacuN, dehydration by the scytalone dehydratase-like protein AacuK and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:33891392).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) AacuH then yields monodictyphenone (PubMed:33891392).  Monodictyphenone is transformed into compounds with the tetrahydroxanthone skeleton via methylesterification by the methyltransferase AacuQ, followed by the action of the flavin-dependent monooxygenase AacuC, the isomerase AacuP, and the short chain dehydrogenase/reductase AacuF or AacuD (PubMed:33891392).  AacuF and AacuD should accept the same compound as a substrate but perform the ketoreduction with a different stereoselectivity, thus yielding blennolides B and A, respectively (PubMed:33891392).  In the final step of the biosynthesis, the cytochrome P450 monooxygenase AacuE accepts blennolide B and/or blennolide A to conduct the dimerization reaction to furnish the tetrahydroxanthone dimers, secalonic acids D, B, and F (PubMed:33891392).
What are the official names of this protein?
Decarboxylase AacuI, Secalonic acid biosynthesis cluster protein I.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: RPOA_BRUA4
Sequence: MIQKNWQELIKPNKVDFITNGSRTHATVVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAIQIDGVLHEFSSIPGVREDVTDIVLNVKEIAIRMEGEGPKRMVVRKEGPGVVTAGDIQTVGDVEILNPDHVICTLDEGAEIRMEFTVNTGKGYVPADRNRAEDAPIGLIPVDSLYSPVRKVSYKIENTREGQVLDYDKLTLNIETNGSVSGEDAVAYAARILQDQLAIFVNFEEPQKEAPQEQVAELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEIPSWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HLYEL_ECOL6
Sequence: MKNKLKSALSFFTTLSNTVKQANKDIDAAKLKLTTEIAAIGVIKTETETTRFYVDYDDLMLSLLKEAAQKMINTCNEYQKRHGKKTLFEIPEV
What are the official names of this protein?
Putative hemolysin E-like protein.
What is the protein family that this protein belongs to?
Belongs to the hemolysin E family.
Protein: SCX2_TITZU
Sequence: IEVVMGGKEGYLLDKSNGCKRSCFFGSTSWCNTECKSKSAEKGYCAWPSCYCYGFSDDSKMWDLKTNKC
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Tz2, P*T-beta* NaTx1.1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y259_COXBN
Sequence: MFSLTQKIGFNAEKTACRYLQKQGLSFITKNFRYKQGEIDLIMSDQSMLVFIEVRYRRFSDFIHPVATVTPLKQRRLIKTALHYLQKHRLLDKISCRFDIVGITADRQITWIKNAIEVEY
What are the official names of this protein?
UPF0102 protein CBUD_0259.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: ATP6_RICFE
Sequence: MTHSPLAQFDIKKLIDIKMFGFDVSFTNSSIYMLLASILALTYFYLAFYNRKLVPSRLQVSAEIVYNLVADMLNQNIGVKGRKFIPLVFSLFIFILFCNLLGMTPYSFTATSHIIVTFTLAILVFLTVTIVGFVKHGLRFLTLFLPHGTPLWLAPLMIVIELFTYLARPVSLSLRLAANMMAGHVLLKVIAGFTVSLMIYLKFLPIPLMVILIGFEIFVAILQAYIFTILSCMYLNDAINLH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACT8_SOLTU
Sequence: AGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDHLMKILTERGYSFTTTAEREIVRDVKEKLSYIALDYEQEIETAKTSSSVEKSYELPDGQVIPIGAERFRCPEVLFQPSMIGMEAAGIHETTYNSIMKCDVDIRKDLYGNIVLSGGTTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQ
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-79.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PHNW_BURM9
Sequence: MPERDPILLTPGPLTTSRMTRDAMLRDWGSWDAAFNRLTKSVCADLVRIAGGGDAYVCVPLQGSGTFAVEATLGTLVPRDARVLVPNNGAYCARIAAILRRLGIAHVELPFAEDEPASAHAIDAALARDARLTHVALVHLETSAGLLNPLDDIAAVCRARGRALIVDAMSSFGALPIALAASGIDALISASGKCLEGVPGMGFAIVRRSALEAAEGRSPSVALDLHDQYAYMQRTSQWRFTPPTHVLAALRAALDQFFDEGGQPARGARYARNCATLVDGMRALGFEPFLDARAQASVIVTFYAPADPAYAFPAFYAAVRDAGYVLYPGKLTTADTFRVGCIGALGADEMRGAVAAIGGALESLGIAMR
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: KGUA_STAHJ
Sequence: MDNEKGLLIVLSGPSGVGKGTVRKEIFDDPTTSYKYSVSMTTRNMREGEVDGVDYFFKTKEEFEALIQEDQFIEYAEYVGNYYGTPVQYVKDTMAAGHDVFLEIEVEGAKQVRKKFPDALFIFLAPPSLDHLKERLVGRGTESDEKIQSRVNEARKEVEMMNLYDYVVVNDEVHLAKERIQSIVEAEHLKRERVEAIYRKMLLEAKK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXD_ALIFS
Sequence: MKDESAFFTIDHIIKLDNGQSIRVWETLPKKNVPEKKHTILIASGFARRMDHFAGLAEYLSTNGFHVIRYDSLHHVGLSSGCINEFTMSIGKNSLLTVVDWLTDHGVERIGLIAASLSARIAYEVVNKIKLSFLITAVGVVNLRDTLEKALEYDYLQLPISELPEDLDFEGHNLGSEVFVTDCFKHNWDTLDSTLNSVKGLAIPFIAFTANDDSWVKQSEVIELIDSIESSNCKLYSLIGSSHDLGENLVVLRNFYQSVTKAALALDDGLLDLEIDIIEPRFEDVTSITVKERRLKNEIENELLELA
What is the function of this protein?
Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction.
What are the official names of this protein?
Acyl transferase, ACT, C14ACP-TE, Myristoyl-ACP-specific thioesterase.
What is the protein family that this protein belongs to?
Belongs to the LuxD family.
Protein: Y181_METEA
Sequence: MIRHTRLLLASLCLIATGARASAEPVQDGQLWINTTLFGSVGDVAYFAEVQPRIGNGISQLDQIILRPAVGWKVNDALVLYQGYAYVEDHGMRDNVRIEDRSFQEINWKIGEFSGVKVSSRTRFEQRWQSAGRDVGFRLRENLRFAMPLPKDWGGVSAVGWTELFVALNDTDWGTRAGFDRVRAFIGLELPIGGKSTVEIGYLNQTARTQASGIELDHILSLNLFVRY
What are the official names of this protein?
Uncharacterized protein MexAM1_META1p0181, ORFB.
Protein: SYGB_GEODF
Sequence: MAKELFLEIGTEEIPAGFLPKAMADMEGLIRKELESARIGFGEVKTMATPRRLALVVKNVSAQQTDAEITTMGPAKKVAFNDDGTTTKAGEGFARGQGVDASALSIIATEKGEYVAVTKKEIGVATAGLLAEILPRLINNIPFKKSMRWGDQEVRFARPMHWIVALFDGTVIPFAFGNVQSGSMSRGHRFMANTSFPVRDFGHYLEECERHFVIPDPAKRKEIISREIERVAKAAGGNVLPDEGLLEQVTYLVEYPSAVHGTFSAEFLAVPKEVLITSMREHQRYFSLVDDKGKLLPGFITINNTLTEDPSVVVKGNEMVLRARLSDARFFFEEDKKVPLEKRVEALKSVLYQAKLGTSYEKMERFRTLAEGLAEQLQPPLKAKVFQAATLCKADLVTGMVGEFPEVQGIMGREYALLQGVDAEVARAIAEHYLPNQAGGELPASDTGAFVSIADKVDTICGCFSVGLIPSGSADPYALRRAALGIINIILAKGYNLPLIPLVTKAIGQLEGRLTRKKEEVLADVLDFFKGRFINLLTDRFPADVVEAVVAVSFDNLVEATAKIEALAQFKKRDDFEPLAVAFKRVCNIVKEQVTVPVDDKLFQDAAEGTLFQSFKSASSMVEEKVVQREYLAALTQIASLKGAVDDFFDKVMVMAEDEGVRNNRLALLQEIKSLFRDIADFGKLTA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_AROAE
Sequence: MALLQIAEPGQSAEPHKHRLAVGIDLGTTNSLVATVRNGIAVCLADEAGRSMLPSIVRYHADGRIEVGQTAAAAHTTDPKNTIMSVKRFMGRGLKDVSHVESTPYDFIDAGGMVRLRTVQGVKTPVEISAEILKTLGARAEASLGGPLTGAVITVPAYFDDAQRQATKDAAKLAGLNVLRLLNEPTAAAVAYGLDNASEGVYAIYDLGGGTFDLSILKLSRGIFEVLATNGDAALGGDDFDHRLFCWILDKAAIEPPTSDDSRRLLMKAREAKELLTASEEAPIRARLSSDEEVNLVVTREEFATMTQHLIAKTMAPMRKVLRDAGLGPEDVKGVVMVGGATRMPHVQRAVAEFFGQEPLTNLDPDKVVALGAAIQANVLAGNRKDEDEWLLLDVIPLSLGLETMGGLTEKVVPRNSTLPIARAQEFTTFKDGQTAMAFHVVQGEREMVKDCRSLARFELRGIPPMVAGAARIRVAFQVDADGLLSVSAREMSSGVEASVLVKPSYGLTDDEIASMLKEGVEHVGDDMHARALREQQVEAERVIEATTHALEQDGALLNADERASIEVAIAELKQLAAGDDPRIVKKGIEALARATDEFAARRMDNSIRSALAGHKVDEIQV
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ASTF_ASPOR
Sequence: MLPTLPNIAGRINTMATFLLPVAIGTIILLFLYGKYVTSTLIPGPPTLPLIGNLHQLPSDDRRHVLAQWHKKHGPIISLKFGWSSVVILGNIAVTKELFGKRSLKYGSRPRMVMARDCMTKQMQTSTLPWGEKWKIHNRIQLSLVGGPKIRSYQSLLDIESCKVLYQLLSTESLVTCFNRFKFNIIYTLAYGKDPDQNESDFHEILELADHFTQTLTNATWVVDLFPILNCLPRRLAPWKAVGDDFHRRAMGWFRRNSEAAVKSNSWNWTKHVQFNEDTGNLSVSEMQYLIGVLFEAGVDSTATVLHFFVLACTLYPDAVTKARQELDKVVGSARLPTPKDLPQLPYVKAFIQEVLRWRPITAEGLPHFTLEDDKYQGYDIPKGSTVIFNYWSGHMDEDTYQHADQFCPERWIERPDLPLGVFGYGRRACAGRRLALMSLETLIPKLLWAFDFRSPAGTDHGKSRDPGTEHQGALIKPRSFPVSWHPVSNDRRLIIERLFQERDKDLDTVLDDIGKAFERY
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of astellolides, drimane-type sesquiterpene esters that show antimicrobial, anti-inflammatory, and anti-tumor activities (PubMed:27628599).  The first step in astellolide biosynthesis is performed by the sesquiterpene cyclase astC that catalyzes the formation of drimanyl pyrophosphate from farnesyl pyrophosphate (PubMed:27628599).  Drimanyl pyrophosphate is then dephosphorylated by the sesquiterpene phosphatase astI to produce drimanyl monophosphate which is further dephosphorylated to drim-8-ene-11-ol by atsK (PubMed:27628599).  Drim-8-ene-11-ol is converted to confertifolin, probably by the cytochrome P450 monooxygenase astD and/or the dehydrogenase astE (PubMed:27628599).  The cytochrome P450 monooxygenases astB, astF and astJ then hydroxylate confertifolin at C6, C14, or C15 to form trihydroxy confertifolin (PubMed:27628599).  The nonribosomal peptide synthetase astA catalyzes ester bond formation between trihydroxy contifolin and benzoic acid (BA) or 4-hydroxy benzoic acid (4HBA), leading to the formation of dideacetyl astellolides A and B, respectively (PubMed:27628599).  Finally, the O-acetyltransferase astG converts dideacetyl astellolides A and B into deacetyl astellolides A and B (PubMed:27628599).
What are the official names of this protein?
Cytochrome P450 monooxygenase astF, Astellolide biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.