PharMolix/UniProtQA huggingface dataset:
Protein: RL15E_SULIK
Sequence: MTLSVYHYIENTWNSEEWKKGVLRQRFIEWRKEPSIVRLAKPTRLNRARSLGYKAKQGFVIVRVRVRRGGLNKPRPNKGRRPKRMGVYGYGPAKGYKWIAEERAARKYPNLEVLGSYYVGEDGLYKYYEIIMVDPSHPVIKNDPNYKWLQDPSNRNRVFRGLTSAGKKARGLRKSKGFKGTVKHKWSRKQKEREEKKRHEASKYYRLQRYDKIPGK
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: K1PF_ECO57
Sequence: MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGINVAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGEVTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQCPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIAHVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLRLATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.
What are the official names of this protein?
1-phosphofructokinase, Fructose 1-phosphate kinase, Fru1PK.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: HIS1_BACAA
Sequence: MRNIQIALTKGRLEKHVIPLFEQIGIDCSELKNKGRKLVFQSKNTDISFILVKAVDVATYVEHGVADIGVVGKDILMENEKDIYEMLDLGVGVCKFCVASIPTYNPKSYRKKCIATKYPHITSNYFHNKGEDVEIIKIEGSVEIAPILGLADAIVDIVETGKTLQENGLIVFEEMYSISARMIVNKAALKTKKDEIFSIINMMEQEILSGK
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBG_CEPBA
Sequence: MVHFTAEEKAIITSLWAKVNVEETGGEALGRLLVVYPWTQRFFDNFGNLSSASAIMGNPKVKAHGKKVLSSLGEAVTHMDDLKDAFAHLSELHCDRLHVDPENFRLLGNVLVIVLAHHFGREFTPQVQAAWKKLMSAVAIALGHKYH
What is the function of this protein?
Gamma chains make up the fetal hemoglobin F, in combination with alpha chains.
What are the official names of this protein?
Hemoglobin subunit gamma, Gamma-globin, Hemoglobin gamma chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ASZ1_LOXAF
Sequence: MAAAVQRGLPVAGGGESSESEDDGWEIGYLDRASQKLTSPLPTEEKNEIFKKALTTGDISLVEELLDSGISVESSFRYGWTPLMYAASVANVELVRVLLDRGANASFEKDKHTVLITACSARGSQEQILKCVELLLSRNADPNVACRRLMTPIMYAARDGHPQVVALLVAQGAEVNAQDENGYTALTWAARQGHKNVVLKLLELGANKMLQTKDGKTPSEVANKNKHPEIFSLLSLTLNPLEGKLQQLTKEETICKLLTTDSDKEKDYIFSSYAAFGDLEIFLYGLGLEHMTDLLKERDISLRHLLTMRKDEFSKNGIASRDQQKILAALKELAVEEIKFGELPEVAKLEISGDEFLSFLLKLNKQCGHLITAVQNIITELPVSSHKIVLEWASPQNFTSVCEELVSNVEDLSEEVCKLKDLIQKLQNERENDPTHIPSVEEASPWRSRILKRTAVTVCGFGFLLFICKLTFQRK
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: GPPA_PHOPR
Sequence: MERNPISPLYAAIDLGSNSFHMWIVREVAGSVQTLAKIKRKVRLAAGLNSQNELSEEAMQRGWDCLSLFAERLQDIPAERVRIIGTAALRTAVNADIFLSKAKDILGSKVDVIPGEEEARIIYQGVAHTSGGSDKRLVVDIGGASTEVIIGEGFDASALTSLKIGCVTWLERYFKDRYLTAENFDAAIDAAKNAIEPIVEQYTQLGWETCVGASGTVQALQEIMLAQGMDEIITLSKLKRMQRQAMQYERLEDLDIEGLTLERALVFPSGLSILIAVFESLNIESMTLAGGALREGMVYEMMSKMRHHDVRERTLTSVQERFQLDTSHASAVTNTAMALLSRCDEEWQLEPQAQYLLHASVCLHEIGTSIEFKKSGEHAAYLINHIDLPGFTRAQKHLIAELLRRFREQLTSLPEQHALSAQNAARILRLLRLAVILCHRRDHNQQPPFSLSVAENKLVLTLPAAWLLANPLSHVELQQEATRQTDMGWPLVLEESE
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: MINC_RHILO
Sequence: MTFAAPLEAKSIRFRARSFVAFTLTPEAPMVEWLQGLDHWIGNSPGYFAGRPVLLDLNVLKPAPSEIAALVAELGTRGIRIYAIELEGASLGPDLPPLLVGAKEATTEGLLPGRKGGQEGSGKPDGKAAEGRAPDHGTEGRADAGAAGKGKAGASKTDESGPQVSHYDSGTLMIKTPIRSGQAIMHAHGDVIVLGSVASGSEIVAAGSIHVYGTLRGRASAGALGNTAARIFCRRNEAELLSVDGWYITAEEMEGVSRGKPVQAFLDGDGLRVETLS
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: SYA_MYCVP
Sequence: MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPYFLGQRTPPWDRAASVQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKKGAIEFAWTLLTNPVEAGGYGFDPERLWATVYLDDDEAIGYWQEVAGLPLERIQRRGMADNYWSMGIPGPCGPSSEIYYDRGPEYGIEGGPEANEDRYIEIWNLVFMQNERGEGTSKEDFEILGPLPRKNIDTGMGVERVACLLQGVDNVYETDLLRPAIDLVAGIAPRGYGQGVHEDDVRYRIIADHSRTAAIIIGDGVSPGNEGRGYVLRRLLRRIIRAAKLLGVDDPIMAELMATVRDAMSPSYPELAADFDRIQRIAVAEETAFNRTLASGSKLFDDAARATKASGAEKLSGRDAFTLHDTYGFPIELTLEMAAEADLSVDEEGFRALMAEQRQRAKADAAARKQAHADLSAYRELVDAGPTEFTGFDELSSEARILGIFVDGKRVPVVAHTGREGAQERVELILDRSPFYAESGGQIADEGTVTGTGASETAKAAVTDVQKIAKTLWAHRINVESGEFVEGDTVVAAVDPRWRHGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGALTDDQRSQIEEVTNQAVEADFEVHSFTTELDKAKAMGAMALFGENYPDEVRVVEIGGPFSLELCGGTHVRSSAQIGPVTILGESSVGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVATLVEKLRAAEKELDRLRLAGARSAAVNAAAGAEQIGDVRLVAQRMAGGISGADLRSLVGEIRGKLGSDPAVVALIAEGDNDSVPFVVAVNPAAQDRGVRADELVKVMGAAVNGRGGGKADLAQGSGKGAAGIDAALAAIRAEIGRS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDFA_ECOL6
Sequence: MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLKDKQMGNSHEG
What is the function of this protein?
Efflux pump driven by the proton motive force.  Confers resistance to a broad spectrum of chemically unrelated drugs (By similarity).
What are the official names of this protein?
Multidrug transporter MdfA, Chloramphenicol resistance pump Cmr.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. MdfA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTCP_RAT
Sequence: MEVHNVSAPFNFSLPPGFGHRATDKALSIILVLMLLLIMLSLGCTMEFSKIKAHLWKPKGVIVALVAQFGIMPLAAFLLGKIFHLSNIEALAILICGCSPGGNLSNLFTLAMKGDMNLSIVMTTCSSFSALGMMPLLLYVYSKGIYDGDLKDKVPYKGIMISLVIVLIPCTIGIVLKSKRPHYVPYILKGGMIITFLLSVAVTALSVINVGNSIMFVMTPHLLATSSLMPFSGFLMGYILSALFQLNPSCRRTISMETGFQNIQLCSTILNVTFPPEVIGPLFFFPLLYMIFQLAEGLLIIIIFRCYEKIKPPKDQTKITYKAAATEDATPAALEKGTHNGNIPPLQPGPSPNGLNSGQMAN
What is the function of this protein?
As a major transporter of conjugated bile salts from plasma into the hepatocyte, it plays a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins (PubMed:1961729).  It is strictly dependent on the extracellular presence of sodium (PubMed:1961729).  It exhibits broad substrate specificity and transports various bile acids, such as taurocholate, cholate, as well as non-bile acid organic compounds, such as estrone sulfate (PubMed:9486191).  Works collaboratively with the ileal transporter (NTCP2), the organic solute transporter (OST), and the bile salt export pump (BSEP), to ensure efficacious biological recycling of bile acids during enterohepatic circulation (By similarity).
What are the official names of this protein?
Hepatic sodium/bile acid cotransporter, Na(+)/bile acid cotransporter, Na(+)/taurocholate transport protein, Sodium/taurocholate cotransporting polypeptide, NTCP, Solute carrier family 10 member 1, SLC10A1.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KPRS1_LISMF
Sequence: MSNEYFDPKLKIFSLNSNRELAEEIAKEVGIELGKSSVTHFSDGEIQINIEESIRGCHVYVIQSTSNPVNQNLMELLIMIDALKRASAATINIVMPYYGYARQDRKARSREPITAKLVANLIETAGATRMITLDMHAPQIQGFFDIPIDHLNAVRLLSDYFSERHLGDDLVVVSPDHGGVTRARKMADRLKAPIAIIDKRRPRPNVAEVMNIVGNVEGKVCIIIDDIIDTAGTITLAAKALREAGATKVYACCSHPVLSGPAMKRIEESPIEKLVVTNSIALPEEKWIDKMEQLSVAALLGEAIVRVHENASVSSLFE
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 1, RPPK 1, 5-phospho-D-ribosyl alpha-1-diphosphate synthase 1, Phosphoribosyl diphosphate synthase 1, Phosphoribosyl pyrophosphate synthase 1, P-Rib-PP synthase 1, PRPP synthase 1, PRPPase 1.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2635_STUS1
Sequence: MDTKLLDILACPLCKGPLKLAEDKSELICKADGLAFPVRDGIPVMLESEARTLDVDERLDK
What are the official names of this protein?
UPF0434 protein PST_2635.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: ARGD_WOLSU
Sequence: MGEALDKEYVLHSYGRNYVQFTQGKNATLWDSEGKDYIDFASGIAVCSVGHGNERLAGAICDQAKKLIHTSNLYYIEPQARLAEKLVKLSGYDMRVFFANSGAEANEGAIKIARKFGESHEGEVKRYKIITLESSFHGRTITALKATGQEKMHHYFGPYPDGFVYAKNLDHVFKLVDEKTCAVLLELVQGEGGIEPQDREGIKKLERFLKERGVLLMVDEVQTGIYRSGELFASQAYGIVPDVITVAKGLAGGVPIGAVMTTLKDIFAPGDHGSTFGGNFLSTRAGLEVLSILESLYQEGTLQKSIDRFSAELRALCVEFPSLFECEVGLGLMRGIRAKSAEIQKSVIDEAFKKRVLVLRSGRNTVRFLPPLTLSEREMQEGFSRLREALKGI
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF4_MESAU
Sequence: VTCFCKRPVCDSGETQIGYCRLGNTFYRLCCRQ
What is the function of this protein?
Bactericidal activity, greater against Gram-positive bacteria.  Low anti-fungi activity.
What are the official names of this protein?
Neutrophil defensin 4, HANP-4.
What is the protein family that this protein belongs to?
Belongs to the alpha-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PI_ECOL6
Sequence: MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_HAEIN
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGSVKEAGGQVHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQQVIDELETTFRYNDAVLRSLVIHTKHAVTEASPMKAAKEERKPLAEVENNDFEDAEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MSHC_CORST
Sequence: MHAWPDPSVPAVAGTPVPLKLFDTADQRVKEVDTTPDANGEVGMYVCGITPYDSTHLGHAATYLTFDLAQRQLLANGHKVHYVQNITDVDDPLFERAERDGVDWRELGTSQINLFRSDMEILSVIPPCDYIGAMESVDEVIAMVQQLLDAGAAYELDQGDIYASIDATEQFGYESNLDRATMEEYFAERGGDPDREGKRDPLDALVWRGHREGEPAWDSPFGPGRPGWHVECSAIATNRLGSHFAIQGGGSDLAFPHHEFSAAHAEAALKVERMAGHYVHAGMIALDGVKMSKSLGNLVFVHKLSEAGHDPSAIRLAVFAGHYREDRDFSDAILAEAEERLTRWREQLAGEVSEAEATEVVDKLRAILADDLNTPEALSLLDGAAGDCNQIIATALDGLLGVRI
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: BSC4_YEAST
Sequence: MSIVLRKSNKKNKNCITSKFYTIHIIKISTPVFRAPIAIGESPYVEWSCLQVVFRKDMVTKKTTFAQLITRLNHFLCQALKRRDSKTYILCRTAVFGAMTPFSPRKSHINNKLPMQPRKKKIVIIYVVRFH
What are the official names of this protein?
Bypass of stop codon protein 4.
Protein: MNME_PELUB
Sequence: MTIYALSTGPGISGIAIVRVSGKDTKKVIKLLTNAALPETRVATLRKINKINTSELIDEGIILWFPGPESYTGEDMAEFHIHGSKAVIDALHHSISKIKNCRLADPGEFTKLAFQNGKINLLKAESIADLISAETEIQRQQAIKIMNGKSADKFNNLREKLLKILSHVEAKIDFPDEDLPEDILKNIKKISNEVILNIKKILDDQKVGERIREGFKIAIIGPTNAGKSSLLNHLSNRDVAIVSEIAGTTRDVIETHLNIDGYPVVVSDTAGIRDSKNEIEKKGIKLALDKADNADLKLIVIDAKSIDFKGVLKELMDENAILVINKSDLLNKDLNSEIKNYEHVLISVKNNLNLEDLISKIKNKLKNKFITSEDILITRARHRQHLEQSLNCLKNFEEKNEAEDFDKAAEDLRLATRHLGMIVGKVDVEEILGSIFNDFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_PSEU2
Sequence: MADEQNLDAQAQDQAAEAGAGDELTTRVQVLEEQLAAAQDQSLRVAADLQNVRRRAEQDVEKAHKFALEKFAGDLLPIIDSLERGLDLSSPDDESIRPMREGIELTLKMFQDTLKRYQLEAIDPHGQPFSADQHQAMAMQESADVEPNTVLKVFQKGYQLNGRLLRPAMVVVSKAPSPATPSINEQA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H8A03_CYRHA
Sequence: MVNMKASMFLTFAGLVLLFVVCYAPESEEKEFPKEMLSSIFAVDNDFKQEERDCAGYMRECKEKLCCSGYVCSSRWKWCVLPAPWRR
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U3-theraphotoxin-Hhn1a 3, U3-TRTX-Hhn1a, Hainantoxin-VIII.3, HNTX-VIII.3, Peptide F4-27.90.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 51 (Hntx-8) subfamily. Hntx-8 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPPX_MYCBP
Sequence: MNDGKRAVTSAVLVVLGACLALWLSGCSSPKPDAEEQGVPVSPTASDPALLAEIRQSLDATKGLTSVHVAVRTTGKVDSLLGITSADVDVRANPLAAKGVCTYNDEQGVPFRVQGDNISVKLFDDWSNLGSISELSTSRVLDPAAGVTQLLSGVTNLQAQGTEVIDGISTTKITGTIPASSVKMLDPGAKSARPATVWIAQDGSHHLVRASIDLGSGSIQLTQSKWNEPVNVD
What is the function of this protein?
Might be involved in translocating phthiocerol dimycocerosates (PDIM) from the cell membrane to the outer membrane; PDIM forms part of the cell wall.
What are the official names of this protein?
Putative phthiocerol dimycocerosate transporter LppX, Lipoprotein LppX.
What is the protein family that this protein belongs to?
Belongs to the LppX/LprAFG lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cell surface. Secreted, cell wall. Secreted.
Protein: Y2593_SHEAM
Sequence: MLNTTFDQYLEFPCSFPFKVVGDASETLADRVVAVVQQHAPGDYSPTSKVSSKGTYLSVTIRVTVTSKDHIETLYTSLAAIEGVKRVL
What are the official names of this protein?
UPF0250 protein Sama_2593.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: RPIA_BIFLS
Sequence: MDKAQQDALKKAAGIEAAKLVENGMIAGLGTGSTVKFLVDELGRRHQEEGLEFTGVTTSRRTQAQAESYGIKIVDIDDVDHIDVTIDGADEVDKNFNGIKGGGAALLWEKIVATNSNQIVWIVDESKVVDTIGKFPLPVEVIPFGAGHVIKKFEACGYKPVLRLDADGKEVRTDENNFVVDLHLERIDHPQELAEDLINTVGVVEHGLFLNMVDKVIVGDPNGPRVMTNANK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: OPTN_XENLA
Sequence: MENELLNHPHNNNMVNGHQDAPYDALSMKNDAEMLEQIKQLLMENNNLKETMKQMNQEMKERLEELLKRHNQHLLDLNSANEVLRKELQSLKEKIATSNQGSAVCSTSEEASENKQLKNQLTRLQAEKADLLGLISELQLKLGSFSEDSFVEIGFSERESGEIVNEEKANKILSDHNISYRTNSIKEEGGGTEPEEVAISRLLRSLREETQKVERLEKELFSANKRLAELEKQTSEFCDKGVQTEQESEQSQSEVIISSEVDILKEKVKSLNKELQETNDKLNEAKQFKNSLQEKCILLDKRLQENQVDLEEKQSLRYSIKKLELQVESQESEIKLEQNKTEAEKNQLGILQVSYDKLNSEYQELRIREIEKVSKVEFNELLEKLDVCEKALAKKQFEIDEMREMDTKHEEDKETIELLRAQVDVYCADFHAERSARENIHQEKEQLATRLAYMIQEYEKLKEEMMGKQSIEQLQRRHGATSLLDASEGPYLVARGAANMEQPSITVYTCPKCNLTVPDMDTLQIHVMDCIT
What is the function of this protein?
Probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death.  May act by regulating membrane trafficking and cellular morphogenesis.
What are the official names of this protein?
Optineurin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle. Recycling endosome. Cytoplasmic vesicle, autophagosome.
Protein: EUTM_SALTY
Sequence: MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAMVRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPISFKGDSNI
What is the function of this protein?
Expression of the eut operon allows this bacteria to use ethanolamine as a carbon, nitrogen and energy source.  It relies on cobalamin (vitamin B12) both as a cofactor for the ethanolamine ammonia-lyase (EAL) activity and to induce the operon (PubMed:3045078).  EA enhances bacterial survival in macrophages in a concentration-dependent manner, suggesting it is an important nutrient during infection (PubMed:29531136).
What are the official names of this protein?
Bacterial microcompartment shell protein EutM, Bacterial microcompartment protein homohexamer, BMC-H, Ethanolamine utilization protein EutM.
What is the protein family that this protein belongs to?
Belongs to the bacterial microcompartments protein family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: FTHS_VIBCH
Sequence: MLPDIEICRATPLAPIDTIAQKAGLHANEYESHGQHKAKVSLHCLERLANKPKGKFILVTAITPTPLGEGKTVTTIGLAQGLAKLNHSVMACIRQPSMGPIFGVKGGAAGGGYSQVAPMEELNLHLTGDIHAVTAAHNLAAAAIDARIYHEQRLGYADFERRTGMPALRIDPKQVIWKRVMDHNDRALRMVTVGRNEPGKNINGYEREDGFDISAASELMAILALASDLRDLRRRIGNVVLAYDLDGNPVTTEDLKVAGAMAVSMKEAIEPTLMQTLEGVPTLIHAGPFANIAHGNSSIIADEIATRLADYTVTEGGFGSDMGFEKACNIKAKASGKTPDCAVIVATLRGLKANSGLYDLRPGQAVPDALFAPDSAALQAGFANLKWHIDNVNQYGVPAVVAINRFPQDCAEELEQLVKLIEALPNRVSVAISEGFAKGGEGTKLLAEKVVEQCQHPTKFTPLYDSGIPLDEKLKAVAVKGYGAAEIALSDKAAQQLAKLQTQGFDHLAVCLAKTPLSISTDPAIKGAPRDFIVPIRELRLCAGAEFVYALCGSVMTMPGLPEKPSFMALDIDQHGNIVGLS
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: FPOC_METMA
Sequence: MDARTIIESLTGKFPEAISEAGIESPIRIRAYVDKDKAKEVCEYLKGSLQFDHLCSVSGVDYPQRDELEAVYHIASYDHPVVLMLKARLPRDSPEIESVVSVYWNANWYERETYELYGIFFKNHPELKPLVLPDDMLGEWPLRKDYEGFPNRTARNLV
What is the function of this protein?
Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2):heterodisulfide oxidoreductase system.  The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines.  Catalyzes the oxidation of methanophenazine to dihydromethanophenazine.  It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane).  It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  It also catalyzes the oxidation of F(420)H(2) with quinones such as 2,3-dimethyl-1,4-naphthoquinone, 2-methyl-1,4-naphthoquinone and tetramethyl-p-benzoquinone.
What are the official names of this protein?
F(420)H(2) dehydrogenase subunit C, F(420)H(2)-dependent phenazine dehydrogenase subunit C, F(420)H(2)-dependent phenazine oxidoreductase subunit C, FPO subunit C, Methanophenazine hydrogenase subunit C, Methanosarcina-phenazine hydrogenase subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.