PharMolix/UniProtQA huggingface dataset:
Protein: UBIB_VIBPA
Sequence: MTPAELKRLYHIIKVQLEYGLDELLPDHQLTKAPLLMRKSLFWIKNQHPEKPLGERLRLALQELGPVWIKFGQMMSTRRDLFPPHIADPLALLQDQVAPFDGELAKQQMEKALGGPLENWFTEFDIKPLASASIAQVHTARLKDTNQEVVLKVIRPDIRPVIDSDLKLMHRMARIVAGAMPEARRLKPVEVVREYEKTLLDELDLRREAANAIQLRRNFEGSEELYVPEVFPDFSNETVMVSERIYGIQVSDIEGLEANGTNMKLLAERGVSVFFTQVFRDSFFHADMHPGNVFVKPEHPENPMWIGLDCGIVGTLNSEDKRYLAENFLAFFNRDYRRVAELHVDSGWVPADTNVDEFEFAIRIVCEPIFAKPLCEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYPQLDLWETAKPFLEEWMMNQVGPQALVNSIKDRAPFWAEKLPELPELLYDSLKQGKAMNQRMDLLYQGYRQSKRQQATGKFLFGVGATLVVCSAILVDNAYEQLSMASGIAGVTFWLLSWRAYRQ
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHI1_MYTCA
Sequence: PSPTRRSKSRSKSRSRSRSASAGKAAKRAKSKTAK
What is the function of this protein?
Involved in nuclear basic protein transition: histones are replaced by spermatid specific proteins which are themselves replaced by protamines in late spermatids.
What are the official names of this protein?
Sperm-specific protein Phi-1, PL-III, Sperm-specific protamine-like protein.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NIKD_SHIBS
Sequence: MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAATLGILPAGVRQTAGEILADGKAVYPCALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LIPB_RHILO
Sequence: MTQRSQIATSFLPLPGSAPVEWRIEPGLTAYPDALAFMEARAEAIRSGGAGEMVWLVEHPPLYTAGTSARIEDLIEPDRFPVFSAGRGGEYTYHGPGQRVAYVMLDLKRRREDVRAFVAALEQWIIGTLAAFNVRGERREDRVGVWVVRPDRPRLPDGSPAEDKIAAIGIRLRRWVSFHGIAINVEPELTHFGGIVPCGVQDHGVTSLVDLGLPVGMADLDLALKSAFEDVFGPVAALPAEVARKTG
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNTB_RHORT
Sequence: MTHSLTMAAYIVAGVLFILALRGLSNPESARNGNRMGMVGMAIAILTTLLSPSVQAYAWIVLAIAIGGAIGTVIAKKVLMTALPQLVAAFHSLVGMAAVLVATGALLNPEAYGIGSAGAIHAGSLVEMSLGLAVGAITFSGSVIAFGKLQGLIAGKPVTFPMQHPLNAVLGILLVVLLVVFAATESHTAYFALMILAFALGFLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGNPLLIIAGALVGSSGAILSYIMCKGMNRSIFNVILGGFGSEGGVAAAGGAAGDRSVKAGSAEDAAFIMKNASKVIIVPGYGMAVAQAQHALREMADVLKKEGVEVSYAIHPVAGRMPGHMNVLLAEANVPYDEVFELEEINSSFQTADVAFVIGANDVTNPAAKTDPSSPIYGMPILDVEKAGTVLFIKRSMASGYAGVENELFFRNNTMMLFGDAKKMTEQIVQAMN
What is the function of this protein?
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
What are the official names of this protein?
NAD(P) transhydrogenase subunit beta, Nicotinamide nucleotide transhydrogenase subunit beta, Proton-translocating transhydrogenase NADP(H)-binding component, Pyridine nucleotide transhydrogenase subunit beta, dIII.
What is the protein family that this protein belongs to?
Belongs to the PNT beta subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PNP_CHLPD
Sequence: MIINKAIDLGKGKILSIETGKMAKQADGAALVRLGDTMVLATVVSSKTPPPANQDYFPLQVEYREKYSAAGKFPGGFFKREGRPSEKEILTARLIDRALRPLFPDGYLFETQIIVTVFSSDQINDADVLGGVAASAAIMVSDIPFHNSMSEVRVGRINGEFIVNPNINELQGSDIDICIGGTANTICMLEGEMKEISEAEMLDAIKFGHEAIRKICALQDEMAAEIARPQRSFAPVKAPAKLKEVIAGLSETRLKELAYTPLCKEDRAEKTASVYKETLQSTLELFKALLTPEEIAAEPEKALCLNAHIIEEEIHAVEKKVMRHMILDDGKRLDGRTLDEIRPISIELGIIPRAHGSALFTRGETQALVTITLGTKKDAQSVDTLTDSADKRFMLHYNFPPFSVGETGRVGGTGRREIGHGNLAERSIKMVSPSETDFPYTIRIVSDILESNGSSSMASVCGGTLALMDGGVPIRKPVSGIAMGLIKEGDAYSVLSDILGNEDHLGDMDFKVAGTEDGITACQMDIKIDGLDYHILETALEQARKGRLHILDKMEVAIPISRGELAQYAPRLTSIQIPVDAIGLIIGKGGETIRSITEETGAEINIEDDGTVTIACSSPEGTNAAVETIKTLISKPEIGNTYLGKVRDIRDELGAFVEFLPKTDGLVHISEISKERVTKVSDHLKVGDRVKVKLVDIRKDPRTGKNRFALSIKAVESEPEKSDENKAGTEGN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_BRUC2
Sequence: MKANIHPDYHTIKVVMTDGTEYMTRSTWGKEGDTMNLDIDPTTHPAWTGGSQTLLDRGGRVTKFKNRFGNLGI
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: NDK_XYLFM
Sequence: MVLERTLSIIKPDAVAKNVIGDIYSRFEKAGLKIVAAKYKQLSRREAEGFYAVHRDRPFFNALVEFMISGPVMIQVLESENAVARHRELLGATNPKDAAPGTIRADFAESIEANAAHGSDSVENAAIEVAYFFAATEIILR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI204_ARATH
Sequence: MQGLAATTTNRGSLTFLAPRNHSPISKKFVNPRVFFPNVDSSAKLRLSASSISRRCPREIAPLSATASVDFAAAATSSNQLFANGLPPLAPGLRRHRRPIEPARVAKDDFFKIKLPKIAERPEWWWRTLACVPYLISLQISDVGFYVQPFLEKHDAIGDMIYFIPGAINRWPTWFFMVYCYLGYMWVVKNKELPHYLRFHMMMGMLLETALQVIWCTSNFFPLIHFKGRFGMYYWMAIGFTYICLLLECIRCALAGVYAQIPFMTDAASIHTLFNLGGFQRPLR
What is the function of this protein?
Involved in protein precursor import into chloroplasts.  Partially redundant with TIC20-I, but not with TIC20-II or TIC20-V.
What are the official names of this protein?
Protein TIC 20-IV, chloroplastic, Translocon at the inner envelope membrane of chloroplasts 20-IV, AtTIC20-IV.
What is the protein family that this protein belongs to?
Belongs to the Tic20 family.
Protein: AROE_MARN8
Sequence: MTNDLYAVVGNPISHSKSPRIHSLFAQQTGEAVEYTAIQAPLEDFAGTVHHFFDHGGKGLNITVPFKEQAWTLAEHRTHRAELAGAANTLYLDQEDQLVADNTDGVGIVRDLRDNHGVPLKGARVLVLGAGGAVRGVLGPLLDEQPASVVVANRTVARAEALARLFGREHSGIELSACGFEQVEGPFDLVINGTSASLKGDLPAITADVIRADTVVYDMMYSLQTTTFNQWALDHGAVRVFDGLGMLVEQAAEAFFVWRGVRPETSAVTEELRTD
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: SOAT1_HUMAN
Sequence: MVGEEKMSLRNRLSKSRENPEEDEDQRNPAKESLETPSNGRIDIKQLIAKKIKLTAEAEELKPFFMKEVGSHFDDFVTNLIEKSASLDNGGCALTTFSVLEGEKNNHRAKDLRAPPEQGKIFIARRSLLDELLEVDHIRTIYHMFIALLILFILSTLVVDYIDEGRLVLEFSLLSYAFGKFPTVVWTWWIMFLSTFSVPYFLFQHWATGYSKSSHPLIRSLFHGFLFMIFQIGVLGFGPTYVVLAYTLPPASRFIIIFEQIRFVMKAHSFVRENVPRVLNSAKEKSSTVPIPTVNQYLYFLFAPTLIYRDSYPRNPTVRWGYVAMKFAQVFGCFFYVYYIFERLCAPLFRNIKQEPFSARVLVLCVFNSILPGVLILFLTFFAFLHCWLNAFAEMLRFGDRMFYKDWWNSTSYSNYYRTWNVVVHDWLYYYAYKDFLWFFSKRFKSAAMLAVFAVSAVVHEYALAVCLSFFYPVLFVLFMFFGMAFNFIVNDSRKKPIWNVLMWTSLFLGNGVLLCFYSQEWYARQHCPLKNPTFLDYVRPRSWTCRYVF
What is the function of this protein?
Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol (PubMed:16154994, PubMed:16647063, PubMed:9020103, PubMed:32433614, PubMed:32433613, PubMed:32944968).  Plays a role in lipoprotein assembly and dietary cholesterol absorption (PubMed:16154994, PubMed:9020103).  Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions (PubMed:11294643, PubMed:32433614).
What are the official names of this protein?
Sterol O-acyltransferase 1, Acyl-coenzyme A:cholesterol acyltransferase 1, ACAT-1, Cholesterol acyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IRAD_ECO45
Sequence: MMRQSRQAVLPEISGNKTSSLRKSICSDLLTLFNSPHSALPSLLVSGMPEWQVHNQSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYSHTLAISLEIMLYHDDEPLTFDLVWDNGGWRSATLENVS
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraD.
What is the protein family that this protein belongs to?
Belongs to the GpW/Gp25 family. IraD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_BORBU
Sequence: MDIKTLKGFKDYLPKDSLIRIHIVRQIFSVLNSYNFDLIDTPVLEYSDLLLKKSGDETEKQIYRFKDNGGRDVSMRFDLTVPFARFVATNISALKLPFRRSQFGKVFRGENSQKGRYREFMQFDFDIVGEDTFRGDAEILSVVYYGLEEIFLNFIEGINKKFIIHYSHIGILNSFFEKLGLKEKSIFILRNIDKIDKIGIDKVKEALLLEIEKEAVDSILSLVSLQGTFKDKIQALKSILGDNESIKRVEDVFQHLSLLKIQDSFNLNLKISRGLDYYTGIVFESEVFGSNMGSVCSGGRYDNLVSSFSNSIQKISGVGGSFGVDRIKDIIDLEKFSYIKIFVTKARSKVLIVNLDSALQNYYYELATRFRNHDYSKVKNISCEVYFKNKNGKNIKEQIEYALSKEIRFLVFVGQEEYKENKMKVRDLTKKEELLLSFEESINLIKCNEKLLCTPF
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_THEVB
Sequence: MTHIRAIYTDGACEGNPGPGGWGVVIYFTDGSVHELGGHHPATTNNRMELQAAIEALKAWRQLAPGSAIALYTDSEYVLRGITEWIHHWKRRGWKTAAKKPVLNQDLWQELDALNDPLVQWHHVRGHRGDVGNERCDLIARRLSRGQPIALRTLPPPLG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_MYCPU
Sequence: MAIVPKRKTSKQRKRKRQTHDALKVSTLVSCQNCSVQTIPHVTCKSCGFYKGRQVLKVKSS
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: DNLJ_SHEB9
Sequence: MQDIQLDTLLSEDVTPENASQVMQALSQSLNEHNIRYYVDDAPSITDSEYDRLMQRLLKLEALYPHLIVADSPTQRVGGLALAKFDQITHLKPMLSLDNAFDEADFSAFHKRVTDKVGEVSFCCEPKLDGLAVSILYRHGVLERAATRGDGSVGEDITENVKTIKSIPLKLRGNDFPELVEVRGEAFMPKAAFEALNDRARAKDEKLFVNPRNAAAGSLRQLDSKITAARSLAFYAYALGVVEPDSHPLAKTHFEQLQQLKSWGLPISSEIKVCAELSQVYDYYKDILTRRSDLAFEIDGVVMKVNDIAQQQRLGFVAKSPRWAIAYKFPAQEEMTLLEGVDFQVGRTGAVTPVARLKPVFVGGVTVSNATLHNADEIARLGIKVGDTVIIRRAGDVIPQIVAIVPERRPETATDIVFPHNCPVCGSLVERLEGEAVARCSGGLFCEAQRKEAIKHFASRKALDIDGMGDKVVEQLIDKELVQSPADLFKLTASMMTMLDRMGMKSATNLAAAIEAAKTTTLARFLYALGIREVGEATAANLAAHFASLDALRVATVEQLTEVEDVGAVVAQHVAHFFAQPHNLEVIDALIAAGVHWPAIEAPSADAQPLKGQTWVLTGTLNQLNRNDAKAQLQALGAKVAGSVSKNTDCLVAGEAAGSKLAKAQELGVKVMDEDELLALLAANA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL32_RENSM
Sequence: MAVPKRKMSRSNTRARRAKWKATAPHLAKTVENGRVTYSLPHQAKVVTDSAGTALFLEYKGRKVADV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: YQGI_BACSU
Sequence: MNRKITDKLATGMFGLCAAIIAAILVGLFSYIIINGVSQLSFQFITTKSSAIAAGGGIRDQLFNSFYILFITMLITIPLGVGGGVFMAEYAPNNKVTDFIRTCIEVLSSLPSIVIGMFGLLMFVNLTGWGYTIIGGALALTVFNLPVMVRVTEDAIRSVPKDLKEASLALGVSRWHTVKTVLIPSAIPSIITGAILASGRVFGEAAALLFTAGLTTPRLNFTEWNPFSETSPLNIFRPAETLAVHIWNVNTQGMIPDAEAIANGGSAVLVISVLVFNLAARWLGTMIYKKLTAN
What is the function of this protein?
Part of the binding-protein-dependent transport system YqgGHIJK.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Probable ABC transporter permease protein YqgI.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SUCC_PSEP1
Sequence: MNLHEYQGKQLFAEYGLPVSKGFAVDTPEQAAEACDKIGGNEWVVKAQVHAGGRGKAGGVKLVRSKEDAKAFAAQWLGKNLVTYQTDANGQPVSKILVESCTDIAKELYLGAVVDRSSRRIVFMASTEGGVDIEKVAHETPEKILKATIDPLVGAQPFQGRELAFQLGLEGKQVQQFAKIFVGLAKLFKDHDLALLEVNPLVIKADGDLHCLDAKINIDANAMYRQPKLKTFHDPSQDDAREAHAAKFELNYVALEGNIGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVTEAFKIILSDSNVAAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGNNAELGAKVLAESGLNIIAATSLTDAAQQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RPOZ_ACIC1
Sequence: MAGTVAVPEGITNPPIDELLKVCDNKYALVIYAAKRARQINAYYAQLGEGLLEYVGPLVETYPTEKPLSIALREINAGLLTAEPIEQ
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SERC_SALDC
Sequence: MAQVFNFSSGPAMLPAEVLKLAQQELRDWHGLGTSVMEISHRGKEFIQVAEEAEQDFRDLLNIPSNYKVLFCHGGGRGQFAGVPLNLLGDKTTADYVDAGYWAASAIKEAKKYCAPQIIDAKITVDGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAIDETPDFGPEVVVTADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHESCPSILDYTVLNDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELLYGVIDNSDFYRNDVAQANRSRMNVPFQLADNALDKVFLEESFAAGLHALKGHRVVGGMRASIYNAMPIEGVKALTDFMIDFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_CITK8
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVEHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCVYVAIGQKASTISNVVRKLEEHGALQNTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNVEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNSGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LSPA_STRGG
Sequence: MAEAERIIGMPENPDVDGTDEGGSTAADAAVNAGRGKRKILALLSVAVVAYLLDLGSKMLVVAKLEHQPPIDIIGDWLQFRAIRNPGAAFGIGEAFTVIFTIIATGVIVVIFRIARKLYSLPWAIALGLLLGGALGNLTDRIFRAPGVFEGAVVDFIAPKNSAVFNLADSAIVCGGILIVILSFKGLDPDGTVHKD
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIC_BACCR
Sequence: MKQSVSAEQIELKSSLPGSKKVYVDGPREGMKVPMREIEQSETNGVPNPPIRVYDTSGPYTDPEYKVELEKGIPTPRHSWILGRGDVEAYEGREVKPEDDGVKVASKHTPVFPQMDRKPLRAKQGANVTQMHYARNGIITSEMEYVAIREGVEPEFVRKEIAEGRAILPANINHPEAEPMIIGRNFHVKVNANIGNSAVSSSIAEEVEKMTWATRWGADTIMDLSTGKNIHTTREWIIRNAPVPVGTVPIYQALEKVNGIAEDLTWEVYRDTLIEQAEQGVDYFTIHAGVLLRYIPITAKRTTGIVSRGGSIMAQWCLFHHKENFLYTHFEEICEIMKQYDVSFSLGDGLRPGSIADANDEAQFSELETLGELTKIAWKHDVQVMIEGPGHVPMHLIKENMEKELDICQGAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVRTGVITYKIAAHAADLAKGHKTAHQRDDALSKARFEFRWRDQFNLSLDPERAMEYHDETLPAEGAKTAHFCSMCGPKFCSMRISHDIREYAKENDLETTEAIEKGMKEKAEEFKEAGSHLYQ
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: URE1_BURTA
Sequence: MSRRAYAEMYGPTTGDRIRLADTELLIEVERDYTIYGEEVKFGGGKVIRDGMGQSQLSAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDTDTQVAIHTDTLNEGGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEPNVLPSSTNPTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQSAHKMKMQRGALAEDSARNDNFRAKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIIKGGMIAVAQMGDPNASIPTPQPVHYREMFATRGGALARTSLTFVSQLTLDAGIGARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAISVDPETYDVVADGALLTCEPAAVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_SALCH
Sequence: MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQLAVDIGREHALFMHLTLVPYLAAAGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISMKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIYEEANPAGEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVTVNIKLIDSQDVETRGVEILKDLDAILIPGGFGYRGVEGKIATARYARENNIPYLGICLGMQVALIEFARNVAGMDNANSTEFVPDCKYPVVALITEWRDEDGNVEVRSEKSDLGGTMRLGAQQCQLSDDSLVRQLYGASTIVERHRHRYEVNNMLLKQIEAAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAANEHQKRQAK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NRM1_YEAST
Sequence: MSIMKQRLPLGEFSSSKINKLAIANIADASEPRNHGENNVGTVCLPSIKSLMVSPEVYENTKSLPVPLMRSSGGGMACASKSSCQDGISTKTTSRDYSELSKKLQIRLQFAYYKYKTKQTDKNFTDLKSKHSITRPSKVATHSKSEPLTRRRKLVLSQGHYKTPARSKIKTPSSICSHDNTSSFTSFRGVSESSSTTADMNVADTTTPIRNNINTKHSNSHNRTLYQRQETPTSIKAAKSLIHLFTSNQ
What is the function of this protein?
Negative regulatory component of the MBF complex involved in cell-cycle-dependent transcription.
What are the official names of this protein?
Transcription factor NRM1, Negative regulator of MBF targets 1.
What is the protein family that this protein belongs to?
Belongs to the WHI5/NRM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: XYLE_ECO57
Sequence: MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIRGKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKGKTLEELEALWEPETKKTQQTATL
What is the function of this protein?
Uptake of D-xylose across the boundary membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
D-xylose-proton symporter, D-xylose transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDXH_ALCBS
Sequence: MKDVREEYHADGLIEATLHDDPLEQARRWVDEAIEAELPLPNAITLATVSANGQPSSRVVLLKGIENQGFTFFTHYDSRKGEEIAANPKVSFTMFWQPFDRQMIVIGEAQKVDQEESDSYFASRPYASQVSAAISPQSRPASREWLEAEVSRLEQEFPSAPVPRPEQWGGYRIIPTEIQFWHGRPSRLHDRFRYVKQGDGCWQRERLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.