PharMolix/UniProtQA huggingface dataset:
Protein: MURE_VIBVU
Sequence: MRNTMNLTNLLAPWLDCPELADITVQSLELDSRQVKQGDTFVAIVGHVVDGRQYIEKAIEQGANAVIAQSCQQYPSGLVRYQQNVVIVYLEKLDEKLSQLAGRLYQHPEMSLIGVTGTNGKTTITQLIAQWLELAGQKAAVMGTTGNGFLNALQPAANTTGNAVEIQKTLADLQQQGAKATALEVSSHGLVQGRVKALQFAAGVFTNLSRDHLDYHGTMEAYAKAKMTLFTEHQCQHAIINLDDEVGAQWFQELQQGVGVSLFPQDASVKALWASSVAYAESGITIEFDGCFGQGRLHAPLIGEFNATNLLLALATLLALGVDKQALLDSAASLRPVLGRMELFQVNSKAKVVVDYAHTPDALEKALQALRVHCTGHLWAIFGCGGDRDKGKRPMMAEIAERLADHVVLTDDNPRSEDPTMIVQDMLAGLTRADSAVVEHDRFSALQYALDNAQADDIILLAGKGHEDYQVLKHQTVHYSDRESAQQLLGISS
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAC_LIMF3
Sequence: MSDPLTHFNDQNRAKMVDVTAKQVTARTATATGTIRMQPATLDRIHAGTMKKGDVLAVAQVAGIMAAKQTSNLIPMCHLIPLTGVDIHFTDNNQDTITATATVKTKHVTGVEIEALLAVQTTLLTIYDMCKAIDRGMVIDNVHLVEKDGGKSGHFQFGEAPESQA
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: CTSR2_RAT
Sequence: MAHERGHLQLPRADAIRSKLIDTFSLIEHLQGLSQAVPRHTLREILDPACQKKLMLGDQEQLVRFSIRARRMGHITHAQRLLSRLRVRCGGRPPLSLWAGWVLDSSIFSNFIISLIFLNTFVLMVEIELMNSTNTSLWPLKLALEVTDWFILLSFIVEILLMWLASFFLFWKNAWSVFDFVVTMLSLLPEFVVLIGVSADSVWLQLLRVSRVLRSLKLFARFPQIKVILLALVRALKSMTFLLMLLLIFFYVFAVAGVYFFKEYSRSTIENLEYNMFFSDLLNSLVTVFILFTLDHWYAVLQDVWKVPEASRVFSSIYVILWLLLGSIIFRNIIVAMMVTNFQNIRNELHEEMTHLEVQYKADIFKRRIIQRRQQSESLRGTSQGKVSEDITETSEATDEEKSEAEESEEEKSEEEKSDVEKSDEEKNDEEKSDEEENDEEKSDVEKSDEEKNDEEKGYTEKVYSGRTFVERSYAERSFAGKAENEKVQKELKEKAYPGSPPNSSSHDEAFAADDTYLENLDWETLVHENLPGLMDMDQDDRVVWPRDSLFRYFELLESLQYNLEERKRLQEFAVQALMNFEDK
What is the function of this protein?
Voltage-gated calcium channel that plays a central role in sperm cell hyperactivation.  Controls calcium entry to mediate the hyperactivated motility, a step needed for sperm motility which is essential late in the preparation of sperm for fertilization.  Activated by intracellular alkalinization.
What are the official names of this protein?
Cation channel sperm-associated protein 2, CatSper2.
What is the protein family that this protein belongs to?
Belongs to the cation channel sperm-associated (TC 1.A.1.19) family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Protein: DPO3B_STAAU
Sequence: MMEFTIKRDYFITQLNDTLKAISPRTTLPILTGIKIDAKEHEVILTGSDSEISIEITIPKTVDGEDIVNISETGSVVLPGRFFVDIIKKLPGKDVKLSTNEQFQTLITSGHSEFNLSGLDPDQYPLLPQVSRDDAIQLSVKVLKNVIAQTNFAVSTSETRPVLTGVNWLIQENELICTATDSHRLAVRKLQLEDVSENKNVIIPGKALAELNKIMSDNEEDIDIFFASNQVLFKVGNVNFISRLLEGHYPDTTRLFPENYEIKLSIDNGEFYHAIDRASLLAREGGNNVIKLSTGDDVVELSSTSPEIGTVKEEVDANDVEGGSLKISFNSKYMMDALKAIDNDEVEVEFFGTMKPFILKPKGDDSVTQLILPIRTY
What is the function of this protein?
Confers DNA tethering and processivity to DNA polymerases and other proteins.  Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA.  Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity.  The beta chain is required for initiation of replication as well as for processivity of DNA replication.
What are the official names of this protein?
Beta sliding clamp, Beta clamp, Sliding clamp, Beta-clamp processivity factor, DNA polymerase III beta sliding clamp subunit, DNA polymerase III subunit beta.
What is the protein family that this protein belongs to?
Belongs to the beta sliding clamp family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNO1_CHICK
Sequence: METEAADESGFTSVASKRGRRKRRAAGAEPMEAAESAEAAGPQPSKRPAFPPLPAAALGVGKGEVRKVPVPANRYTPLKENWMKIFTPIVEHLQLQIRFNLKTRNVEIKTCSETKDLSALTKAADFVKAFILGFQVEDALALIRLDDLFLESFEVTDVKPLKGDHLSRAIGRIAGKGGKTKFTIENVTRTRIVLADSKIHILGSFQNIKMARTAICNLILGSPPSKVYGNIRAVASRAAERF
What is the function of this protein?
Positively regulates dimethylation of two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA.
What are the official names of this protein?
RNA-binding protein PNO1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MATK_RORAM
Sequence: MXXXXGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNRNRSIFFENVDYEKKYSSLIVKRLILRMYEQNRLIIPSKDLNQNHFFGHTSLFYYQMISVLFAVIVEIPFSLRLGSSFEGKQFKKSYNLQSIHSIFPFLEDKLSHFNYVLDVVIPYPIHLEILVQTLRYRVKDASSLHFFRFCLYEYCNWKDFSIKKKSILNPRFFLFLYNSHVCEYESIFFFLRKRSSHLRSTSYEVLFERILFYGKIQHFLKVFINSFPAILGLLKDPFIHYVRYHGRCILATKDTPLLMNKWKYYFVNLCQCYFSVWFQSQKVNINQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNVRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKAVWTDSSDSDILNRFVRISRNISHYYSGSSNKKNLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQVLSLIFPRSYYASKRLYRVRIWYLDILYLNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MAT_INCJJ
Sequence: MAHEILIAETEAFLKNVAPETRTAIISAITGGKSACKSAAKLIKNEHLPLMSGEATTMHIVMRCLYPEIKPWKKASDMLNKATSSLKKSEGRDIRKQMKAAGDFLGVESMMKMRAFRDDQIMEMVEEVYDHPDDYTPDIRIGTITAWLRCKNKKSERYRSNVSESGRTALKIHEVRKASTAINEIAGITGLGEEALSLQRQTESLAILCNHTFGSNIMRPHLEKAIKGVEGRVGEMGRMAMKWLVVIICFSITSQPASACNLKTCLKLFNNTDAVTVHCFNETQGYMLTLASLGLGIITMLYLLVKIIIELVNGFVLGRWERWCGDIKTTIMPEIDSMEKDIALSRERLDLGEDAPDETDISPIPFSNDGIFEI
What is the function of this protein?
Ion channel, which might have a role in genome packaging and uncoating processes.
What are the official names of this protein?
Polyprotein p42.
What is the protein family that this protein belongs to?
Belongs to the influenza C protein M1 family.
What are the subcellular locations of this protein?
[Polyprotein p42]: Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Protein M1']: Virion membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Protein CM2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: PRIM_MUHVS
Sequence: MTVVLFATEYDTPNIVVNMLSETPTEHHLFPLMIKYKPSNRIEFVLQTQRCPDSTRVRPVFICDARRLSLSEYVSTNTPLPARVICAGIDADATRELYEHLFDRKKDETGHDEENGSAARHLFSNLTSTLKCLVHYNRSAILRYLNNTFLSPTFPSWFLSTYGTHEGTLILTMSYYLFERTYSTIQTTRDYTKCFTADPGRNLFTYINMRDFMATMNGSRFRKQTVLFAVFAKARNARDRCELEYVDAKINAFREESRLAADSCVYYVYLAYRTALCREKFLQYCEHTAYDKNLPDDQQCAAEENYLGRSLDAELISIMNTYFSVEGYFGSYIHVDRAKLSPPHSYRGYDWNTEADTMVGYSSTATNLAISLRKLNSTCESLFSPLPPTLMGLLKLCASDRYVPRAEKSRKRTSGGREKEDETRVCRRNYLLNDTSRPIGPMPVFRVEMPEKRHVFCAVSAENWTRRLLPKDLMKNLPSEYVSDECLTDAVWLREDIAALCEVGEQLYRTRHEMFNENLPVFNFVGDVDLKLREDLQGLSRQEVFDLCRALRRTLIGAWRHLFPEVDPDSHPVFFFKSACPQNAAGAADEAMLYGGGGYDEDDDPRPEHAAAMVDYGDAVRRPPFCVCRRKLGLRVIIPFPPRTAAIGAQTLKRLAGILDHTLCLDRDLVCKLNAISHPGECFDTGIYSHGRSIRMPLMYKLDEASGLILHSRLNPIFIVPAGYRDRPAEFVLQQLCPQNLTHHGRPPQRDGSADQLTEVVLHITDRACADSDGNFLQSRARRAMSSGRLPLGPLLRAHLSLESGQSAPSLPTLVGRGGGGEGGASSDYEEERAVGSDEEEDDDDVENLQAFARRIAWPALLRHTRNHYREEVQQQLEAATVFTAVGRTCVAVKRGLYGRARDFSCLARETYTRQETVQVFLDIRGDQRRNVWATLWSRCFTRRCNSNAKQTHLSLKISLPSQY
What is the function of this protein?
Essential component of the helicase/primase complex.  Unwinds the DNA at the replication forks and generates single-stranded DNA for both leading and lagging strand synthesis.  The primase initiates primer synthesis and thereby produces large amount of short RNA primers on the lagging strand that the polymerase elongates using dNTPs.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae DNA primase family.
What are the subcellular locations of this protein?
Host nucleus. Note=Requires the presence of the primase associated factor to properly localize in the host cell nucleus.
Protein: NEP_I07A0
Sequence: MDSHTVSSFQDILMRMSKMQLGSSSGDLNGMITQFESLKLYRDSLGEAVMRLGDLHSLQHRNGKWREQLGQKFEEIRWLIEEVRHKLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SPC25_HUMAN
Sequence: MVEDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFSLHLNEARDYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANVRKAFTATVYN
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:14699129, PubMed:14738735).  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:14738735, PubMed:14699129).  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).
What are the official names of this protein?
Kinetochore protein Spc25, hSpc25.
What is the protein family that this protein belongs to?
Belongs to the SPC25 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase (PubMed:14738735). Localizes specifically to the outer plate of the kinetochore (PubMed:14738735, PubMed:14699129).
Protein: Y3754_GLOVI
Sequence: MDRRHRFALQAEIWVADHLAAQGGLVLARRWRCRGGEIDLVVRLGGVLCFVEVKARGGNSWDSAGWEAVGAVKQRRLLLAAALFLAAHPELARSVCRFDVALVGRDPGGGVRLVAYIAGAFEGSGR
What are the official names of this protein?
UPF0102 protein gll3754.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: MOS1_ARATH
Sequence: MTSSTTGDRRWGTTRRSGMTILGKVAVPKPINLPSQRLENQGLDPNVEIVPKGTLSWGSKSSLNAWGTSSLSPRTESGPGSPSHLSNRPSSGGSVTRPSTADSNKAHDSSSSVAWDSNSRPSSASGVFPSNQPSVALQRPHSADTRPGSSQLSRFAEPVSETSATWGQHVAPEKLGVAPSKNDGFSLTSGDFPSLGAEKDTSEKSTRPQDAGPHARPPSSSGRSVEGQGVDCTEEANDRIGDANSWRRENQPYSEDAPRHCREEGQLDSRGSQSYPNANFPPRYDAWRGPPVNNHQGGGWYGGNHPYGAPMGPGGFHMDPFPFYPTQVPPAPGHGAGPRGNHANNERMFRPPMLDSYVHPRMQTRPGFYVGPAPHEGYYGPPMGYGSPSNRDLPFAGRPTGPHAYNNHSGQGGYDTPGSSVSLERNESSHSQETQRPYKVLLKHQDGRFGEDNAKREEFLGNRLPNAEKIAQQMQTSRNERREIRNDASGEVQPVKAELAAPGDPSLIQKIEGLNAKTRTNDGWQNSSSVVNRDEQESQPRTLNSGNSANKVSARNHRTGHASDSKNSSHYNQGDSATNKNAEPAAMGGTSIFRRPTQQTQGRADPQTKRIVNSEGNDAWQKTTVMSGSSHTTLATNTESFREVNVDDSLDTESIRRPGSGISADPKDNQRSTMRELARQRAQQRQKEEEERARDQRAKALAKLEELNRRSQIYEEGSVKNMEAASNASPADMPTDPGSHSSNATNSVEPTGGSGKNTTQNTRTSTEYANNVGPSQQDNLPRDGGASKQKRLGYKQKQNIIFEKKPTGSSVATAEVFDVVPSPEVVNEGVSSNNSDMPATSTVSAESTFPKRKNNRNGKKKHKAEETATMNTTRVAVGKETKSGDESIETARARAAEIELGSVSVPSLDIKVSGDSSEQISSFTNEESQNRAKNNWKSQHVRRTQRNSLVNKPAEKFSGNNAVIWAPVHPQQKADVSTGGGSQTTVPEFGTSSKSQHQGQTSSKSKRVEIERYVPKPIVKEMAEQIVSKNLVTSAPDMSENVNQKENRGGEGTGILQPSGSTAGKSGSPSKSRHGNGRQGKHGREHASWHQRGSGAPTKALEDGQFVTSNQPIRGTVNYHSSKQTEQIAAKDQTTCNKDGWNDGWYMTPETHYSAAEEMESSAVGKDQGMSMHGRQHASRSNKDGGSNYGDPKKGNKRDFNKAHTQHSGHGFSQPDLPAASKEGRVPGDHVWHTANRTGKYGGRESTRDKPYGSQEKNVVGYEHQGFTTEQKTTSADTQAQLQNRSTNKEVQVEQNPNSMFQKNTGQGRRFGRGQESQGGWGLPAQENMHHHHQRPPSNRDRQKQNLHYEYKPVGSHTYDGERSREQSKESSQTEGPRYREKGQGQQRQGGYQQQRGTSGRNGGHGFTGDRN
What is the function of this protein?
Involved in the regulation of the chromatin structure and DNA methylation at the SNC1 locus.  Regulates the expression of SNC1 at chromatin level.
What are the official names of this protein?
Protein MODIFIER OF SNC1 1, MODIFIER OF snc1, 1.
Protein: VG61_BPML5
Sequence: MRRVLITGSRIWKDRTTVWEALATEYHRSFSGLTVVHGGARGADDIADRWAWGMKQEGWDVLPELHRADWERYGKRAGILRNIEMVRAGADICLAFPLGNSVGTRHCMREAERAGIPVINFGDRL
What are the official names of this protein?
Gene 61 protein, Gp61.
Protein: COBQ_SYNR3
Sequence: MTPPTPLMVLGTSSGAGKSLMTAALCRVLKRRGEQPLPFKGQNMSNNAWVDQSGGEMAYSQALQSWAAGLEPNCAMNPVLLKPQGNSTSEVIHGGESVGMARAETYYQEWFKPGWLAIRQGLEQLRQQHPHGRLVLEGAGSPVEVNLQHRDLTNLRLAQYLRARCLLVADIERGGVFAQLVGTLQLLRPVERPLVKGLLINRFRGRQELFDPGVSWLSDNTGVPVLGVMPWLDELFPPEDSLDLLERRGRKANAELEIAVLRLPSLSNFSDLDPLEAEPSVQLRWVQPGEALGQPDAVVLPGSKQTLRDLKALQASGLARELQRFSAGGGAVLGICGGLQMLGRELLDPDGLEGAAGASAAGLNLLPLQTRFGGSKALRQRQAVAHWPTAESCPIEGFELHRGSTIALEPLQALCQEEGLGWVQGQVAGSYLHGLLENGRWRRQWLNQLRRRKQLPELAEDQGHHSLQREELLDRLADAFEANVDLTPLISDP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: F104B_HUMAN
Sequence: MGGCPVRKRRRNGSKEGNHHSTQPKRNKRNPIFQDSQDTEFSWSDNERSSSRINIPERASGPEGNLNQIVTEPDANFPQFLHEGLSKPVYVINWFMSFGPEIKLNTSQQGRNQAV
What are the official names of this protein?
Protein FAM104B.
What is the protein family that this protein belongs to?
Belongs to the FAM104 family.
Protein: POA1_PICGU
Sequence: MSKLNYIKGDLFSHKSSASSILAHACNCRGSWGAGVAAIFKKQFPSTYKLYVEHCKKHASNPSGLLGSTYLIKSESSDPGNSGRENVAYVACMFTSDAFGRRKNSADDIVENTDKSMLHLESQLAELAKTEPIEQQDGVNVVNMPKINAGLFNVPWEETEAVLKKHQVLINVYVI
What is the function of this protein?
Highly specific phosphatase involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing.
What are the official names of this protein?
ADP-ribose 1''-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the POA1 family.
Protein: SUV3_DROME
Sequence: MQNCRRCISLTGLLRMTLYLRPSFSIDLSLRRLHRAAFLFSRKKPETNLSTLFKPVQVHAYVDSEDVGSELSGKLEKAELLKILNKFTQRREIKSLCNENGLDDYLQQQAFGSFRRFCIEAENLPVDLHITFSDITQGAGHIDDIFPYFLRHAKTVFPHLDCMDDLKKISDLRQPANWYSNARAITRKIVFHAGPTNSGKTYHAMERYLSAKTGVYCGPLKLLATEVYNKANERGTPCDLVTGEERKFGISESLPANHVACTVEMTSVNTPYEVAVIDEIQQIRDPQRGWAWTRAFLGLIADEVHVCGEPGALDLLQKICETTGETVEVRLYDRLTELTVENTALGSLDNIVPGDCIVCFSKHDIYTVSREIEARGKEVAVIYGGLPPGTKLAQAAKFNDPANSCKVMVATDAIGMGLNLSIRRIIFYSLIKPSMNERGEREIDTISVSSALQIAGRAGRFRTQWEHGYVTAFKSEDLQTLQRILARTPEPIKQAGLHPTADQIELYAYHLPSSSLSNLMDIFVNLCTVDDSLYFMCNIEDFKFLAEMIQHVALPLRARYVFCCAPINRKMPFVCSMFLKVARQYSRNEPITFDFIKKNCGWPFKLPKTILDLVHLEAVFDVMDLYLWLSYRFMDLFPEAAYVRDAQKELDEIIQQGVFQITRLLKNTEASQDGETSNYAIRRITHVKEPRLPSLSRGRLTERLLAQGLLTPGMLSELRKEWDAQQLGKSNSQSNENSEPVVNSDDEDNYSGIGRKTRKKRRK
What is the function of this protein?
Major helicase player in mitochondrial RNA metabolism and maintenance (PubMed:26152302).  Likely component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner (By similarity).  ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction (By similarity).  Regulates mRNA stability and is required for the correct processing and maturation of mitochondrial transcripts (PubMed:26152302).
What are the official names of this protein?
ATP-dependent RNA helicase SUV3 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Unlike in mammals, does not localize to the nucleus.
Protein: ACT1_PSEMZ
Sequence: YPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPK
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.  Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth (By similarity).
What are the official names of this protein?
Actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: NDC80_CHICK
Sequence: MRRSSTTSGSSGRQSTMVLRVQDSNKMGLQTPQTKDRGTFGKLSMSKTTSATSERKVSFFGKRASGAGGSRNSQYGMFGTEKIKDPRPLHDKAFIQQCIKQLCEFLVENGYAHNVTIKSLQSPSVKDFIKIFTFIYGFLCPSYELPDSKFEEEIPRVFKELGYPFPLSKSSMYTVGAPHTWPQIVAALIWLTDCFKLYAAMRENPSSFDDGQNWGGETDDGIVHNKLFMDYVVKCYEHFMKGGDTYEELDAEVQSKLKDLFNVDEFKIEGLAAENKRLHEEIARLEKERESEPDRLVSLRKLRSSFQADVQKYQAYLANLESHTTILDQKMKSVNEEVETTEMEVEAMKQENARLQHIFDNQKYSVADIERINHERNELQQTINKLTKELEAEEHQLWNEELKYARNKEAIETQLAEYHKLARKLKLIPISAENSKGHDFEIHFNPEAGPNCLVKYRTQIKAPLMEIVNQTEEEIRKATQRKMSLEDTLEQVNAMVAEKKSSVKTLKEEAEKLDDLYHQKLKEAEEEEQKCANELELLEKHKQLLESGVNEGLSEATNELHDIQRQYQIVMQTTTEESRKAGDNLNRLLEVITTHVVSIEKYLDEQNSKIDRDYEEFMSEDLLSTLTGILDSYKKKAESI
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:12829748).  Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore.  The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules.  May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores to spindle microtubules (By similarity).
What are the official names of this protein?
Kinetochore protein NDC80 homolog, Kinetochore protein Hec1, Kinetochore-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. Localizes specifically to the outer plate of the kinetochore.
Protein: PCP2_MOUSE
Sequence: MAGSPDQEGFFNLLTHVQGDRMEEQRCSLQAGPGQNPESQGGPAPEMDNLMDMLVNTQGRRMDDQRVTVNSLPGFQPIGPKDGMQKRPGTLSPQPLLTPQDPAALSFRRNSSPQPQTQAP
What is the function of this protein?
May function as a cell-type specific modulator for G protein-mediated cell signaling.
What are the official names of this protein?
Purkinje cell protein 2, Protein PCD-5, Purkinje cell-specific protein L7.
Protein: YCF2_BUXMI
Sequence: MKRHQFKSWIFELREILREIKNSHSFLDSWTKFDSVGSFTHIFFHQERFMNLFDPRIWSILLSRDSQGSTSNRYFTIKGVVLFVVTVLIYRINNRNMVERKNLYLMGLLPIPIPMNSIGPRNDTLEESFGSSNINRLIVSLLYLPKGKKISESCFLDPKESTWVLPITKKCIMPESNWGSRWWRNWIGKKRDSSCKISNETVAGIEISFKEKDIKYLEFLFVYYTDDPIRKDHDWELFDRLSPRKKRNIINFNSGQLFEILVKHWICYLMSAFREKRPIEVEGFFKQQGAESTIQSNDIEHVSHLFSRNKWGISLQNCAQFHMWQFRQDLFVSWGKNPHESDFLRKVSRENWIWLDNVWLVNKDRFFSKVRNVSSNIQYDSTRSIFVQVRDSSQLKGSSDQSRDHFDSIRNEDSEYHTLINQREIQQLKERSILWDPSFLQTERTEIESDRFPKCLSGYSSMSRLFTEREKQMNNHLLPEEIEEFLGNPTRSIRSFFSDRWSELHLGSNPTERSTRDQKLLKKQQDVSFVPSRRSENKEMVDIFKIITYLQNTVSIHPISSDPGCDMVPKDEPDMDSSNKISFLNKNPFLDLFHLFHDRNRGGYTLHHDFESEERFQEIADLFTLSITEPDLVYHKGFALSIDSYGLDQKKFLNEVFNSRDESKNKSLSLADPPIFYEENESFYRRIRKKSVRISCGNDLEDPKQKIVVFASNNIMEAVNQYRLIRNLIQIQYSTYGYIRNVSNRFFLMNRSDRNFEYGIQRDQIGNDTLNHRTIMKYMINQHLSNLKKSQKKWFDPLISRTERSMNRDPDAYRYKWSNGSKNFQEHFVSEQKSRFQVVFDRLRINQYSIDWSEVIDKKDLSKSLRFFLSKSLLFLSKSLLFLSKSLPFFFVSFGNIPIHRSEIHIYELKGPNDQLCNQLLESIGVQIVHLNKLKPFLLDTSQKSKFLINGGTISPFLFNKIQKWMIDSFHTRNNRRKSFDNTDSYFSMISHDRDNWLNPVKPFHRSSLISSFYKANRLRFLNNPHHFWFYCNKRFPFYVEKARINNYDLTYGQFLNILFIRNKIFSLCVGKKKHAFLERDTISPIESQVSNIFIPNDFPQGGDETYNLYKSFHFPIRSDPFVRRAIYSIADISGTPLTEGQIVNFERTYCQPLSDMNISDSEGKNFHQYLNFNSNMGLIHTPCSEKYLPSEKRKNRSLCLKKCVEKRQMYRTFQRDSAFSNLSKWNLFQTYMPWFLTSTGCKYLNFTLLDTFSDLLPILSSSKKFVSIFNDIMHGSDISWPIPQKKWCLPQWNLISEISSKCLHNLLLSEEMIHRNNESPVPLIWAHLRSPNAREFLYSILFLLLVAGYLVRTHLLFVSRASSELQTEFEKIKSLMIPSYMIELRKLLDRYPTSELNSFWLKNLFLVALEQLGDSLEEIRGSASGGNMLLGGGPAYGVKSIRSKKKYLNINLIDLISIIPNPINRITFSRNTRHLSRTSKEIYSLIRKRKNVNGDWIDDKIESWVANSDSIDDEEREFLVQFSTLTTEKRIDQILLSLTHSDHLSKNDSGYQMIEQPGSIYLRYLVDIHKKYLMNYEFNRSCLAERRIFLAHYQTITYSQTSCGANSFHFPSHGKPFSLRLALSPSRGILVIGSIGTGRSYLVKYLATNSYVPFITLFPNKFLDDKPKGYLIDDIDIDDSDDIDDSDDIYDSDDIDDLDTELLTMTNALTMYMTPKIDRFDITLQFELAKAMSPCIIWIPNIHDLYVNESNYLSLGLLVNYLSRDCERCSTRNILVIASTHTPQKVDPALIAPNKLNTCIKIRRLLIPQQRKHFFTLSYTRGFRLEKKMFHTNGFGSITMGSNARDLVALTNEALSISITQKKSIIDTNTIRSALHRQTWDLRSQVRSVRDHGILFYQIGRAVAQNVLLSNCPIDPISIYMKKKSCKEGDSYLYKWYFELGTSMKKLTILLYLLSCSAGSVAQDLWSLPGPDEKNWITSYGLVENDSDLVHGLLEVEGALVGSSRTEKDCSQFDNDRVTLLLRSEPRNPLDMMQNGSCSIVDQRFLYEKYESEFEEGEGALDPQQIEEDLFNHIVWAPRIWRPCGNLFDCIERPNELGFPYWARSFRGKQIIYHKEDELQENDSEFLQSGTMQYQTRDRSSKEQGFFRISQFIWDPADPFFFLFKDQPFVSVFSRREFFADEEMSKGLLTSQTNPPTSIYKRWFIKNTQEKHFELLIHRQRWLRTNSSLSNGSFRSNTLSESYQYLSNLFLSNGTLLDQMTKTLLRKRWLFPDEMKIGFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TYY1_MOUSE
Sequence: MASGDTLYIATDGSEMPAEIVELHEIEVETIPVETIETTVVGEEEEEDDDDEDGGGGDHGGGGGGHGHAGHHHHHHHHHHHHPPMIALQPLVTDDPTQVHHHQEVILVQTREEVVGGDDSDGLRAEDGFEDQILIPVPAPAGGDDDYIEQTLVTVAAAGKSGGGASSGGGRVKKGGGKKSGKKSYLGGGAGAAGGGGADPGNKKWEQKQVQIKTLEGEFSVTMWSSDEKKDIDHETVVEEQIIGENSPPDYSEYMTGKKLPPGGIPGIDLSDPKQLAEFARMKPRKIKEDDAPRTIACPHKGCTKMFRDNSAMRKHLHTHGPRVHVCAECGKAFVESSKLKRHQLVHTGEKPFQCTFEGCGKRFSLDFNLRTHVRIHTGDRPYVCPFDGCNKKFAQSTNLKSHILTHAKAKNNQ
What is the function of this protein?
Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; proposed to target the INO80 complex to YY1-responsive elements.
What are the official names of this protein?
Transcriptional repressor protein YY1, Delta transcription factor, NF-E1, UCR-motif DNA-binding protein, Yin and yang 1, YY-1.
What is the protein family that this protein belongs to?
Belongs to the YY transcription factor family.
What are the subcellular locations of this protein?
Nucleus. Nucleus matrix. Cytoplasm. Note=Associated with the nuclear matrix. In testis, localized to heterochromatin of spermatocytes.