PharMolix/UniProtQA huggingface dataset:
Protein: TRHO_ECO45
Sequence: MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKVTRDALYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGVIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPDEQRRRRAGRENGNKIFNKSRGRLNTTLGIPDPTE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-carboxymethoxyuridine (cmo5U) biosynthesis.  May be part of an alternate pathway, which is able to bypass cmo5U biogenesis in a subset of tRNAs under aerobic conditions.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PSRP_CUPMC
Sequence: MRTVFIVSDGTGITAETFSHSILAQFEMRFRKVRMPFVDTPDKAHVAVGKINEAFYNEGVPPIVFTTLVNAESNKAIRRAKAMILDMFQTFIEPLEKELGLKSTHAIGRFHQNADTEAYKNRIEAINFSLAHDDGQSHKNLEDADVILVGVSRSGKTPTSLYLAMQYGLKAANYPLIPDDFERGRLPSALYAYKQKIFGLSIDPQRLTEIRNERRPGSKYAAVENCRYEVNEAESMMRREGIKWLSSTHKSIEEIATTILQEIKVDRDNY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: METK_BUCAP
Sequence: MTEYLFTSESVSEGHPDKIADQISDALLDEIIKQDLKARVACETYVKTGMVLIGGEITTTAWVDVEEITRNTINNIGYINSETGFDANSCAVLSTIGKQSPDITQGVDRCNPLEQGAGDQGIIFGYATNETEVLMPAPITYAHLLVKKQSELRKKNILHWLRPDAKSQVTFKYKNGRIIGIDTVVFSTQHKESITQDVLKEAVMEEIIKPVLPNKWLTKNTKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMSRHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLSYAIGIAEPTSIMIETFRTGKISNKSLINLVRNIFDLRPYGLIEMLDLLRPIYLNTAVYGHFGREEFPWEKLDKVDELLQ
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP_BOTFO
Sequence: IIGGDECNINEHRFL
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SL3_BITGA
Sequence: MGRLIFLSFGWLVVFLSLSGTGADFQCPSEWSAYGQHCYRAFSDLKTWEDAEKFCTEQEKAGHLVSIQSIQEANFVAQLVSGFISGSPKIYIWIGLRDRRKEQQCSSEWNDGSKVIYVNWREGESQMCQALTKWTEFHQWLNTDCAGHYPFICKSRV
What is the function of this protein?
Interferes with one step of hemostasis (modulation of platelet aggregation, or coagulation cascade, for example).
What are the official names of this protein?
Snaclec 3, C-type lectin 3.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: DCAM_HELAN
Sequence: MTSAIGFEGFEKRLEISFFNPGPSVDPVARGLRSLTKNQLDKFLAPAECTIVSSLSNDLLDSYVLSESSLFVYPYKIIIKTCGTTKLLLSIPHILELSGELSLTVQSVRYTRGSFIFPGAQTFPHRSFTEEVMVLDSHFGKLGMCSNAYVMGGAEKDQKWHVYSASAESANLVTQTAPVYTLEMSMTGLSKRNASVFFKSESSSAAVMTEDSGIRKILPESQICDFDFDPCGYSMNAIEGDAISTIHVTPEDGFSYASFEAVGYDFKSMGLTVLIERVLACFEPSEFSVALHGNENVVKDLNLENNDVNVKGYNVEETKFEVLGGEGGSMVYYGFARGGSSCGSPRSTLHRCWSETENEEE
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: TPS16_SOLLC
Sequence: MELCTQTVPADHEVEITRRVGSHHPTVWGDHFLAYANLSGASEEEEKQHEDLKEEVRKMLVMAPSNALEKLELINTIQCLGVAYHFEHEIESYMCTHYEEYWIGDLHAIALCFRLLRQQGYRVSCDAYKKFTDDQGNFKIELINDVHGMLSLYEAAQFRVHGEEILDEALNFTTTQLKLILPKLSNSPLAQQVANALKFPIKDGIVRVEARKYISFYQQNQNHNQLLLNFAKLDFNILQMLHKKELCDITRWWKELEIVKTLPYVRDRLAEVYFWSLGVYFEPQYSTARKILTKNISMISLIDDTYDIYGTLDELTLFTEAIERWNIDASEQLQLPSYMKIIYCGLLDVYDEIKKDLANENKSFLINYSIIEMKKMVMAYFQEAKWYYGKTIPKMEEYMKNGISTSAYVQIATTSWLGMGNVATKDSFDWIVNEPPILVASSIIARLLNDLLSHEEEQKRGDAPSGVECYMKEYGVTKEEAHIKIRNTIENSWKDLYEEYFKVNGTIIPRVLLMCIINLARVIEFIYKDEDAYTFPKNNLKDVIYRILIDPII
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:21818683).  No activity detected with geranyl diphosphate (GPP) and farnesyl diphosphate (FPP) as substrates (PubMed:21818683).
What are the official names of this protein?
Terpene synthase 16, SlTPS16.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: MNTH_ECO7I
Sequence: MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGLLLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVALNIWLLVGTALGL
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EX7L_BACSU
Sequence: MGEAAYVTVSALTKYIKRKFDVDPHLENIWIKGELSNVKIHTRGHIYFTLKDENARMQSVMFARQSERLPFKPENGMKVLVRGGISVYEPSGNYQLYAKEMQPDGVGALYLAYEELKKKLAGEGLFDDRYKKQIPAFPATIGVVTSPTGAAVRDVITTLKRRYPLVKVIVLPALVQGENASRSIVTRIEEANEKEICDVLIVGRGGGSIEELWAFNEEIVARAIFASNIPIISAVGHETDFTISDFVADIRAATPTGAAEIAVPHTTDLIERTKTAEVRMTRAMQQHLGQKKERIQTLQSSYAFRFPKRLYAQKEQQFDLAYQQFQAQLTALLDRKSRQLERETYRLEALHPHEQLKQARTRYQEQTNQLRKNMNIQMKQLHSQFQTVLGKLNALSPLQVMERGYSLAYKEDKLIKSVSQIEEQDRLEIKLKDGVLTCEVLEKRGEEK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN_LEUMM
Sequence: MTEPIIELKNIDVTFHQKKRTIEAVKNVSINIERGDVYGIVGYSGAGKSTLVRVINLLQEPTSGSVTVNGETFFQADSQDAKKTRIGTNDLRVRRRKIGMIFQHFNLLNERTVTENVAFALQHSKLKDDEKKAKVAELLELVDLSDRAEQYPSQLSGGQKQRVAIARALANDPEILISDEATSALDPRTTNQILALLKKLNQEFGLTIVLITHEMQAVKEVANKVAVMQNGEIIERGSLLEIFAQPKQQLTREFIETATNIDKAIETIRHEPLVNELKEGEIFARLSYVGETTDEPLIASLFRDFNVTANILYGNIEVLQDTPVGSLLVILSGEPTQVQTALSTLHDHHVEVTILKGGN
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GPSB_PEDPA
Sequence: MDNINFTPKDILQKEFKPKMRGYDPADVDTFLDSVIKDYENFGKEIERMKNENDRLTDKVDELNKQVSAGGTVEESAPVSGATNVDVLKRLSNLERRVFGAQLEDTDNSSHRI
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: HXD3A_DANRE
Sequence: MQKATYYDNAGLFGGYSYPKSDSYTYGPTHQGFSSSSIENDYQSPICPIQTTSVRQATHKNGDINGSCMRPSASQGNSQPESISEQQQAAPLAASSPSPSTNSTQKKKSPSSNGSSTATPVISKQIFPWMKETRQNAKQKSTNCPAAGETCDDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKSKGIMHSPLGHSPDRSPPLSGSNHIGYSGQLPNVNSLSYDAPSPPSFAKPQQNIYGLAAYTAPLGGCIPQQKRYPGTEYDHHSMQGNGSFANANLQSSPVYVGGNFVDSMPASGPMFNLGHLPHPSSASVDYSCAAQIPGNHHHGPCDPHPTYTDLSSHHASQGRLQDAPKLTHL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D3a, Hox-D3.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_SHEPC
Sequence: MAKKIDAYIKLQVKSGSANPSPPVGPALGQKGVNIMEFCKAFNARTEKMEKGMPIPVVITVYSDRSFTFETKTPPASFLLKTAAGLKSGSPRPNTQKVGTIARAKIQEIAETKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: TIG_HELPY
Sequence: MNLEVKKIDTANARLSAKLSIENLEKRYDKIAQKIAQKVKIDGFRRGKVPLSLVKTRYQAQIEQDAQEEMIQEVLKNAFKELGIENKDLIGSPNLTKFEKKDTHFEIEADIGLKPTIVLDKIKECVPSVGVEVPNEEKIDERLKQLAKDYAKFVDTNTQRKAQNDDKLTIDFEGFIDNAPFEGGKAENFNLILGSKQMLEDFEKALLGMQAGEEKEFPLTFPSKYHAEHLAGKEAFFKVKLHQIQAREMLEINDELAKIVLANEENATLKLLKERVEGQLFLENKARLYNEELKEKLIENLDEKIVFDLPKTIIEQEMDLLFRNALYSMQAEEVKSLQESQEKAKEKRESFRNDATKSVKITFIIDALAKEEKIGVHDNEVFQTLYYEAMMTGQNPENLIEQYRKNNMLAAVKMAMIEDRVLAYLLDKNLPKEQQEILEKMRPNAQKIQAG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RPC3_EMENI
Sequence: MASQYAAELCMLLVEDNFGELFGRIFSTLHRYERLTLPRLLGLTRLSENRLRAALVAMIQHHLVHFYTAVEEGGVTYYSANMQAAYYLIRSGKILEFVEDRLGKYAATVMSTIMYLGHAQVSHLDTLPELRSDASKTNGVNEGEHDRPEGENETNGTNGEHVSDQPALLHPTLKALAGHGYIVRVREAHFQSIADNILNIERQIRSGDSVQSMKGKKLEEFVVEKTADMLKERLDGDLTRGLIVNGVPRGVKRSQTNGVSDDNETEKARFDYDDGEDEDEENEWLDDEVPMESSLTVRVNYEKLDVALRNRRFLELAERGAPPESAQIYDYLLRRIEYQTSKCRDASEIPREGEEGEQYSVPIPLSALARDIDPYLDLAGSLGPTNTPANNRLGKRTFDDTVDDNDDDHGATGNRTYEIDQHLSLLAQPPLNLTSKRLNGGIINWTVEFRHLARKLRHLELERIVEARYGDVALRVLRVLQAKGKLDEKRLQEISLLPFKDLRQVLASMQTGGFVDLQEVPRDAQRQPSRTIYLWYYDPDRARDSMLQDTYKAMSRCLQRLKFERGRLKDFLEKTERSDVKGNEELYLSEGELDRLREWRAKEALLIGEVARLDDMIAVMRDY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit rpc3, RNA polymerase III subunit C3.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COPB2_HUMAN
Sequence: MPLRLDIKRKLTARSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTYRLESTLNYGMERVWCVASLRGSNNVALGYDEGSIIVKLGREEPAMSMDANGKIIWAKHSEVQQANLKAMGDAEIKDGERLPLAVKDMGSCEIYPQTIQHNPNGRFVVVCGDGEYIIYTAMALRNKSFGSAQEFAWAHDSSEYAIRESNSIVKIFKNFKEKKSFKPDFGAESIYGGFLLGVRSVNGLAFYDWDNTELIRRIEIQPKHIFWSDSGELVCIATEESFFILKYLSEKVLAAQETHEGVTEDGIEDAFEVLGEIQEIVKTGLWVGDCFIYTSSVNRLNYYVGGEIVTIAHLDRTMYLLGYIPKDNRLYLGDKELNIISYSLLVSVLEYQTAVMRRDFSMADKVLPTIPKEQRTRVAHFLEKQGFKQQALTVSTDPEHRFELALQLGELKIAYQLAVEAESEQKWKQLAELAISKCQFGLAQECLHHAQDYGGLLLLATASGNANMVNKLAEGAERDGKNNVAFMSYFLQGKVDACLELLIRTGRLPEAAFLARTYLPSQVSRVVKLWRENLSKVNQKAAESLADPTEYENLFPGLKEAFVVEEWVKETHADLWPAKQYPLVTPNEERNVMEEGKDFQPSRSTAQQELDGKPASPTPVIVASHTANKEEKSLLELEVDLDNLELEDIDTTDINLDEDILDD
What is the function of this protein?
This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type.  It binds to Golgi membranes in a GTP-dependent manner (By similarity).
What are the official names of this protein?
Coatomer subunit beta', Beta'-coat protein, Beta'-COP, p102.
What is the protein family that this protein belongs to?
Belongs to the WD repeat COPB2 family.
Protein: RL21_CHLL3
Sequence: MQALIEISDKQYLVKKGDTLFVPRQQTAIGDTMEISSMATIDGANTVLNPAVSVKAKVLGHVKDDKVVVFKKKRRKRYQSRNGHRQQMTQIEVVSL
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: MDFA_ECO57
Sequence: MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLKDKQMGNSHEG
What is the function of this protein?
Efflux pump driven by the proton motive force.  Confers resistance to a broad spectrum of chemically unrelated drugs (By similarity).
What are the official names of this protein?
Multidrug transporter MdfA, Chloramphenicol resistance pump Cmr.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. MdfA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATG9_NEUCR
Sequence: MADGVIARLMSGGRGARSFYEELRGRDNVSDVDDRAGLLDEENLNQHFNDYDLENAEGLRLEDSRATVDGRIPRGRAQLSGRPPRPAATTHWGTSHDDDGDNDVPASLLVERYDRGAAPLGSPGKPRSQHAGSRAHPAPGLSKGRTHQQRPHIDQELQPPLHSDAAPSSLLAGAITGNAKKMAEWRWANITNLDSFMQDVYSYYRGSGMWCIVVERVLHLIKVAFVAFLLTFLSQCVDFKKIPSNQKLSQVLVPQCTRNMSGLWNIGLWLFAFYFMWKSIQYILDLRRLTHVRDFYIHLLNIPDEDMQTITWQEVVARIMVLRDQNVRTTRTITPQNQRWVLGSQSKERLDASDIANRLMRRENYMIAMINKDILDLTIPLPILRNRQLLSQTLEWTLMFSILDFVFDPKGQVHQEFLRSDRRGILSAKLRSRFIFAGVMILILSPFVAGYLIIVYFLEYYNEIQKNPSILSARSYTPLAEWKFREFNELPHLFKRRLDMSHPFASHYIDQFPKAKTSMVAKTVSFIAGSIATVLALISVFDPEMFLGFEITHDRTVLFYTAVFGAIWSVARGSVSEDNAVFDPEYALGNVVEYTHYQPEHWKDRWHSADVKAEFEELYKLKLVIFIEEILSILTTPFVLFFSLPKSADQIIDFFREFTIHVDGLGYVCYFAEFDFKKGSKSQAPAATAGEGDVRDDYYSTKHGKMEASMYGFINNYARNPKHLPPAMRQQFHLPPVFPGITSPTLAGDLAASRMGRSQRGRSKGPLPSRTPRPGAVMAEPSPMASILLDPRHQPIFPNNMSFVNTGHQFRGGNQGDGHMMGGGSMEEDVKGAARHGQQTHDDESEDSRAGLDESAWQVSPTKDLSRENSGRGLDSVVGEEAGNGAGVVHMLYQFNQAHLNRRLGGVR
What is the function of this protein?
Phospholipid scramblase involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation.  Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome.  Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through atg-2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.  Required for mitophagy.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.
What are the official names of this protein?
Autophagy-related protein 9.
What is the protein family that this protein belongs to?
Belongs to the ATG9 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HEM1_KOCRD
Sequence: MVLFCLVASHRTVDLNTVARLSTGALGVAEDAVSRGALAGAITLSTCNRLELYGELPEHASVDVPGAQQQLAERIARRAGLDERFVLETMDAYEGPEVPRHLFTVVSGLESAVVGEREITGQVRRALAGAQQSGTASPHLVQLFEAAARTAREVGASTGLGERGRSIVSVALDLADDITSGDWPERHALVFGTGAYAGATMAALRDRGCADIEVYSGSGRAQQFTDQRGGSPVTDESLPGALRRADVIIGCSGGSAPMPASRFPAGPRTVVDLALARDFDPAVADLPNVELITLESVRVAAPEETRESVAAAREIVERAARDFENARTARSMDQAIVALRKHTMAVLDAELDKVRTHHGCTGAEEQIEMAMRRMVRSLLHTPTVRARQLAAEGRADEYITGLEALYGLEVAVPDVPEETAPSTRQDPSDTPRPRAVG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: TAER_MYCTU
Sequence: MSPAEREFDIVLYGATGFSGKLTAEHLAHSGSTARIALAGRSSERLRGVRMMLGPNAADWPLILADASQPLTLEAMAARAQVVLTTVGPYTRYGLPLVAACAKAGTDYADLTGELMFCRNSIDLYHKQAADTGARIILACGFDSIPSDLNVYQLYRRSVEDGTGELCDTDLVLRSFSQRWVSGGSVATYSEAMRTASSDPEARRLVTDPYTLTTDRGAEPELGAQPDFLRRPGRDLAPELAGFWTGGFVQAPFNTRIVRRSNALQEWAYGRRFRYSETMSLGKSMAAPILAAAVTGTVAGTIGLGNKYFDRLPRRLVERVTPKPGTGPSRKTQERGHYTFETYTTTTTGARYRATFAHNVDAYKSTAVLLAQSGLALALDRDRLAELRGVLTPAAAMGDALLARLPGAGVVMGTTRLS
What is the function of this protein?
Involved in the reduction of the double bond between C-4 and C-5 during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis.
What are the official names of this protein?
Trans-acting enoyl reductase.
What is the protein family that this protein belongs to?
Belongs to the saccharopine dehydrogenase family. Enoyl reductase subfamily.
Protein: FRIHA_XENLA
Sequence: MQSQVRQNFHSDCEAAINRMVNMEMYASYVYLSMSYYFDRDDVALHHVAKFFKEQSHEEREHAEKFLKYQNKRGGRVVLQDIKKPERDEWGNTLEATQAALQLEKTVNQALLDLHKLASDKVDAHLCDFLESEYLEEQVKAMKQLGDYITNLKRLGVPQNGMGEYLFDKHTLGESS
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Ferritin heavy chain A, Ferritin H subunit A, Ferritin heavy chain 2, XL2-17.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: ARGR_ANAD2
Sequence: MTSADRRRDAVARIIRARRIGTQEELLAALERAGFRATQATLSRDLARLGARRVSGPEGAVYELGADGADGGLAALRGLVSSIAANASMVVIRTHPGSAPAIARAIDLAQPPEVLGTIAGDDTIFVAPAGELRPRRLAARLAELLGTPSALAGEGGERTH
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM04_AJECN
Sequence: MPSRTITRLVRLYGGTPLVELPPIFLAPALQFPSLHFASFQCLKFSTTPAPGLKLDLSKHRGVSAIHRTGPRYPLSVSKYPLPRPVKPKEQEKRPSNPKHGLWGFFGPDRKPIPTPEEEYAHGRAWSIQELRQKSWDDLHKLYWLCVKERNRIATARYERQRLQAGYGDYESNNRDKTVRGTQQSIKQVLRERWYAWEDARQLYESGEYSPADAQVMEAEAYAYEPPALDVEEPKGEASDSVKTPPSS
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ECNA_CITFR
Sequence: MMKRLLGLVMLLLFTCTLLTGCNTARGFGEDIKHLGNSISHAAS
What is the function of this protein?
Acts as antidote to the effect of entericidin B.
What are the official names of this protein?
Entericidin A.
What is the protein family that this protein belongs to?
Belongs to the EcnA/EcnB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: CLPS_MARN8
Sequence: MRTIENSLLVFNQGEDEQPGRHEGVSVAPEKPALKRPARYRVVLLNDDYTPMDFVVDVLMKFFAMNEEKATQVMLLVHTQGKAVCGVYTRDIAETKAAQVNQYSSECEHPLLCEIERAD
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: YAJC_TREPA
Sequence: MCPARSRMKTMPHRTLLQITTANGGWIPPLAIGVVCLIFYLFVFAPNLREQKRTQALIKNIKKGDPVVTIGGIHGVVSVVREHSLVIKVNEHGTLEVSRSAIARINDRRGVSNPKTDCDSKPGVPLTGVDKEIAR
What is the function of this protein?
The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes.  While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
What are the official names of this protein?
Sec translocon accessory complex subunit YajC.
What is the protein family that this protein belongs to?
Belongs to the YajC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL3_AQUAE
Sequence: MPLGLIGEKVGMTRVLLKDGTAIPVTVIKFPVNYVVQVKSQNTKDGYNALQIGAYEAKEKHLTKPLIGHFKKHGVPLLRRLWEFRVDNPEEFQSGQQLKVEDVFKPGDLVDVWGISKGRGFAGAMKRWDFAGFPKSHGHRYHRAVGAIGQRTDPGRVWKGKRMPGHYGAKPVRVQGLFVVDVLPEENAILVKGSVPGHNKGIVVVEQSTIAYRKSQKLKQKRYQFIIENLAKEESQEVAES
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CH10_PARP8
Sequence: MNLRPLHDRVIVKRLDQETKTASGIVIPDAAAEKPDQGEVLAVGPGKRDDKGAPIALDVKVGDRVLFGKYAGQTVKVDGNELLVMREEDIMAVVNK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.