PharMolix/UniProtQA huggingface dataset:
Protein: TRPD_RIPO1
Sequence: MTQDSTNLWPELLQQLLDKQSLSQLQASQLMEGWLSEAIPPVISGAILVAIQLKGVSGDELAGMAQVLQSQSLNETSIKHTEPVIDTCGTGGDGASTFNISTAVAFVAAAAGVKVAKHGNRSASSKVGSADVLEYLGVKLSAPSEKVAGALDEVGVTFLFAPGWHPAMKYVAPLRKTLKVRTIFNLLGPLVNPLRPTGQVIGVYSPEFMMPMAEALNQLGISKAMVIHGREKLDEAGLGDATDMALLTEKTLGSGYLMPSELGLTFAPLSALKGGEVEENAAILKAVLQGKGTVAQLDAVALNASLALQVGEVVPWGDHRQGIATAKEILNSGVAWDKLEELVKFLR
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PA1_VESVE
Sequence: GLLPKCKLVPEQISFILSTRENRNGVFLTLDSLKKGGILNKSDLSSTQVVFLIHGFISSANNSNYMDMTKALLEKNDCMVISIDWRNGACTNEFQILKFIGYPKAVENTRTVGKYIADFSKLLMQKYKVSLANIRLIGHSLGAQIAGFAGKEYQKFKLGKYPEIIGLDPAGPLFKSNDCSQRICETDAHYVQIIHTSNNLGTERTLGTVDFYMNNGYNQPGCYYSFIGETCSHTRAVQYFTECIRHECCLIGVPQSKNPQPVSKCTRNECVCVGLNAKRYPKTGSFYVPVESKAPYCNNKGKKI
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity).  May act as an allergen and induce hemolytic activity (By similarity).
What are the official names of this protein?
Phospholipase A1, PLA1, Vesp v 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROD_STRSY
Sequence: MKIVVPIMPRNLEEVEAIDVERLAEADIVEWRADYLLKDDILRVAPAIFEKCSGKEVVFTIRTTREGGHLDLDDQEYVNVIKEVATLYQPDYIDFEYYSYKSVFEQMLEFPNLVLSYHNFEETPSNYMEIMSELTSLSPAVVKMAVMAKTEQDVLDVMNYTRGFKSLNTEQIFATIAMGELGKLTRIAGVITGSCWTFASLDETSAPGQMSLSNTRKFLEILEN
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: SAS3_PRIMG
Sequence: MARTNKLLTPGVEQFLDQYKYEIAQEFGVTLGSDTAARSNGSVGGEITKRLVQQAQAHLSGSTQK
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
What are the official names of this protein?
Small, acid-soluble spore protein C3, SASP.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: PYRD_ROSCS
Sequence: MLYHLIRPLLFRLDAERAHDVVTAMFRATSRMPLLPRLISALYAWDDPALMVEWAGLRFASPLGVAAGFDKRADLVDALALLGFSHVEVGTVTPRPQPGNPGPRLFRLPEDMALINRLGFNSHGMVAVAKALRARRSRRVIVGVNIGKNRDTPLERAVEDYAATFVALAPLADYVAVNISSPNTPGLRRLHERAALEELLRELMRLNHGLLYPRPIALKISPDETLDQIEEVVRAGCEAGVAAFIATNTTLAREGLRSRLANETGGLSGRPLAPRARQVIRAIYRLTRGTPPVIGVGGVLTADDAYAHIRAGARLVQLYTGMVYAGPAIAREIKRGLAQLLRRDGFVSVTQATGVDAEWEGAIRQRG
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ASTA_SALDC
Sequence: MRVIRPVEHADIAALMQLAGKTGGGLTSLPANEATLAARIERALKTWSGELPKGEQGYVFVLEDSETGEVGGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPEWRKEGNGYLLSKSRFMFMAAFRDKFNEKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSEEAQAVIGEVHPQTAPARAVLEKEGFRYRHYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAPGDYPACLVANENYHHFRAALVRADPQTSRLVLTAAQLDALKCRAGDHVRLVRLCAEEKTV
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: CARA_CAMJE
Sequence: MKAYIYLENDIFLSAKAFGKSGTFFGELVFNTSLTGYQEIISDPSYAGQFIVFSMPEIGIVGTNENDNESKEIFASGVLMRELSSSFSNFRAKESLQDYLEKHGKIGIYELDTRYLVKMIRNNGNLRAVISTEISNKEDLKIALEKSAKIDEVNFVKEVSTKKNYSHKQGVWNASFQKFNDAKRSEKKVAVIDYGVKTNILNELVEVGFEVEVYPYNVKADELITLYKKGEIQGVFLSNGPGEPRILKQEIAEIKKLAEAKIPMLGICLGHQLLSNAFGYETYKMKFGQHGANHPVINLDTKTVEITAQNHNYNVPEELAQVAHITHRNLFGDNVEGVRYKDYPIISVQHHPESSSGPHESKYIFKEFMNLM
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: DRD2_RAT
Sequence: MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
What is the function of this protein?
Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (PubMed:1321233).  Positively regulates postnatal regression of retinal hyaloid vessels via suppression of VEGFR2/KDR activity, downstream of OPN5 (By similarity).
What are the official names of this protein?
D(2) dopamine receptor, Dopamine D2 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: VE6_HPV20
Sequence: MATPPSSEDSADEGPSNIGEAKFPILEPPLPATICGLAKLLEIPLDDCLIPCNFCGNFLTHLEVCEFDEKKLTLIWKDHLVFACCRVCCSATATYEFNQFYESTVLGRDIEQVTGKSVFDIHVRCYTCMKFLDSIEKLDICGRKRPFYLVRGSWKGICRLCKHFQ
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: ATL43_ARATH
Sequence: MSSSSLILLFSTLSLFLNVSLADNHTAVVITTSDTPPPLPPPSPPPRHNFTSSLMPGIAVVIAVLTAFFSLTFLLLLYVKHCKRRNGSVYVNHPQRFAITRYGGGYYNGGGVVGGRKNSGIDRSVIESLPVFRFGALSGHKDGLECAVCLARFEPTEVLRLLPKCKHAFHVECVDTWLDAHSTCPLCRYRVDPEDILLIGDCNSWFELQFSKDESNSVNNNPPGLTRFIPVSRISGRHSSAGERASRLNEIRTSSSYKSNPMSFRRSLDSSLKVNDAGEEKSESVAVNCLDRLQRKDGLLLIPNRESFEGRFEHRIIISGGNRDDQRWSEVRPSDLLYLRSEMILSDCRKLAAAEGGRDVINGRSVSELTGIERRRRWGGEPRQRQATAVISRWLAWSHRASASSIV
What are the official names of this protein?
RING-H2 finger protein ATL43, RING-type E3 ubiquitin transferase ATL43.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THIM_SOLM1
Sequence: MPFAAAVFADLARIRQNAPLVVNITNNVVTNATANALLALGASPAMTHHPADAAELAALAGALVCNMGTPGGENIEAMLAAGGAANAGGVPVVFDPVAAGVTSRRREVAGRMLETVRLAAVRGNASEILALAGEAALSKGADSQHASREAAPAAVALARSLGCTVCVSGEVDVVTDGERVVELAGGHAMMTRVTGLGCTATAFVGAFLAVNPDYFAATCHAMAVMAAAGRLAAAGVAGPGSLAVRFLDVVYSLTEAEIAAGARVSA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: CLPP2_CHLCV
Sequence: MTLVPYVVEDTGRGERAMDIYSRLLKDRIVMIGQEITEPLANTVIAQLLFLMSEDPKKDIKVFINSPGGYITAGLAIYDTIRFLGCDVNTYCIGQAASMGALLLSAGTKGKRYALPHSRMMIHQPSGGIIGTSADIQLQAAEILTLKKHLANILSECTGQSVEKIIEDSERDFFMGAEEAISYGLIDKVVSSAKDTKDKDTIS
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 2, Endopeptidase Clp 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP1_MYCTU
Sequence: MADPKTKGRGSGGNGSGRRLVIVESPTKARKLASYLGSGYIVESSRGHIRDLPRAASDVPAKYKSQPWARLGVNVDADFEPLYIISPEKRSTVSELRGLLKDVDELYLATDGDREGEAIAWHLLETLKPRIPVKRMVFHEITEPAIRAAAEHPRDLDIDLVDAQETRRILDRLYGYEVSPVLWKKVAPKLSAGRVQSVATRIIVARERDRMAFRSAAYWDILAKLDASVSDPDAAPPTFSARLTAVAGRRVATGRDFDSLGTLRKGDEVIVLDEGSATALAAGLDGTQLTVASAEEKPYARRPYPPFMTSTLQQEASRKLRFSAERTMSIAQRLYENGYITYMRTDSTTLSESAINAARTQARQLYGDEYVAPAPRQYTRKVKNAQEAHEAIRPAGETFATPDAVRRELDGPNIDDFRLYELIWQRTVASQMADARGMTLSLRITGMSGHQEVVFSATGRTLTFPGFLKAYVETVDELVGGEADDAERRLPHLTPGQRLDIVELTPDGHATNPPARYTEASLVKALEELGIGRPSTYSSIIKTIQDRGYVHKKGSALVPSWVAFAVTGLLEQHFGRLVDYDFTAAMEDELDEIAAGNERRTNWLNNFYFGGDHGVPDSVARSGGLKKLVGINLEGIDAREVNSIKLFDDTHGRPIYVRVGKNGPYLERLVAGDTGEPTPQRANLSDSITPDELTLQVAEELFATPQQGRTLGLDPETGHEIVAREGRFGPYVTEILPEPAADAAAAAQGVKKRQKAAGPKPRTGSLLRSMDLQTVTLEDALRLLSLPRVVGVDPASGEEITAQNGRYGPYLKRGNDSRSLVTEDQIFTITLDEALKIYAEPKRRGRQSASAPPLRELGTDPASGKPMVIKDGRFGPYVTDGETNASLRKGDDVASITDERAAELLADRRARGPAKRPARKAARKVPAKKAAKRD
What is the function of this protein?
The C-terminus (residues 622-934) inhibits RNA cleavage by MazF4.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: ALL3_ASPFL
Sequence: DSGGLTPPHADCVPGKXQXNGNYGAVPNKKQQ
What are the official names of this protein?
Allergen Asp fl 3, Allergen Asp l 3.
Protein: GOG8C_HUMAN
Sequence: MAEETRQSKLAAAKRKLKEYWQRNSPGVPAGAKRNRKTNGSIHETATSGGCHSPGDSSSTSSSLHAPQSPCQELAVVPDSRSVKVSQLKNTIKSLKQQKKQVEHQLEEEKKANNEKQKAERGLEVQIQRLNIQKGKLNTDLYHTKRSLRYFEEESKDLAVRLQHSLQRKGELERALSAVTATQKKKAERFSSRSKARMEWKLEQSMREQALLKAQLTQLKESLKEVQLERDEYAEHLKGERARWQQRMRKMSQEVCSLKKEKKHDKYRVETLERSLSKLKHQMAEPLPPEPPAVPSEVELQHLRKELERVAGALQAQVEYNQRISLLNEGQKERLREQEERLQEQQERLREQEERLQQLAEPQNSFKELNNENKSVLQLEQQVKELQEKLGKRLAHPVASAQKEPEAAVPAPGPGGESSGFMDHLEEKADLSELVEKEELGFFQYYRERCHQKVYHPITKPGGSAKDAAPGGGHHQAGPGQGGDEGEAAGAAGDGVAAGGDYKGHSKFLVTAQNPAHEPSPGAPAPQELGAAHKHGDLCEVSLTDSVEPVQGETREGSPHDKPTAQPIVQDHQEHPGLGSNCCVPFFCWAWPPRRRR
What are the official names of this protein?
Golgin subfamily A member 8C.
What is the protein family that this protein belongs to?
Belongs to the GOLGA8 family.
Protein: CYB_MUSPF
Sequence: MTNIRKTHPLTKIINNSFIDLPAPSNISAWWNFGSLLGICLIIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYMFTETWNIGITLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAAVHLLFLHETGSNNPSGIPSDSDKIPFHPYYTIKDILGALLLILMLTLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALIFSILILAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFMILLVLMPIISIIENNMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LEPA_MYCLB
Sequence: MSWSLRVDKPDTGESPFKHSLVTGAQEIPISSFADKTFTAPAQIRNFCIIAHIDHGKSTLADRMLQLTGVVDERSMRAQYLDRMDIERERGITIKAQNVRLSWSVTAGGTTENYVLHLIDTPGHVDFTYEVSRALEACEGAVLLVDAVQGIEAQTLANLYLALERDLTIIPVLNKIDLPAADPDRYAAEIAHIIGYESGDVLRVSGKTGEGVSDLLDEVVRRVPHPQGDPDAPTRAMIFDSVYDIYRGVVTYVRVVDGKISPRERIAMMSTGATYELLEVGIVSPEPKASAGLGVGEVGYLITGVKDVRQSKVGDTVTTVRYGATEPLTGYREPKPMVYSGLYPVDSSDYPSLRDALGKLQLNDAALTYEPETSVALGVGYRCGFLGLLHIDITRERLEREFDLDLISTSPNVVYRVVTEDNTEIVVTNPSDWPEGKIRTVYEPVVKITIIAPSEFIGTIMELCQSRRGELGGMDYLSPERVELRYIMPLGEIIFDFFDSLKSRTRGYASLDYEEAGEQEAQLVKVDILLQGEAVDAFSAIVHKDSASAYGNKMTNKLKELIPRQQFEVPVQAAIGSKVIARENIRAIRKDVLSKCYGGDITRKRKLLEKQKEGKKRMKTIGRVEVPQEAFVAALSADAAGDKDKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GPDA_PSEP1
Sequence: MTEQQPVAVLGGGSFGTAVANLLAENGVPVRQWMRDPAQAEAMRVNRENPRYLKGIRLHDGVEPVNDLLATLQASELIFVALPSSALRSVLAPHAELLRGKALVSLTKGIEAQSFKLMSQILEEIAPEARIGVLSGPNLAREIAEHALTATVVASEHEDLCQQVQAVLHGRTFRVYASADRFGVELGGALKNVYAIIAGMAVALGMGENTKSMLITRALAEMTRFAVSQGANPMTFLGLAGVGDLIVTCSSPKSRNYQVGYALGQGQSLEEAVSRLGEVAEGVNTLKVLKTKAQQVQVYMPLVAGLHAILFEGRTLNQVIEHLMRAEPKTDVDFISISGFN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_BURP0
Sequence: MAGHDSGNAKRGRSPSFGVFVRKPVERAPAKGASDGAVDSQAIRIDAAQSWPDDAVEVGAVVDAYGLKGWVKLAAHAGAGRGGDALLKARDWWLQKGAERKFARVTQAKLHGDTVVAHPGGSVDRDTALALRGARVFVRRGDFPALAADEFYWVDLIGLDVVNEAGVALGKIADMIDNGVHSIMRVEYPATGKDGRPKTGERLIPFVGVYVKAVEQAAGRVVVDWEADY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKF_SERP5
Sequence: MSEFSQTVPELVAWARKNDFSISLPTERLAFLLAIATLNGERLDGEMSEGELVDAFRHVSKGFEQTHETVAVRANNAINDMVRQRLLNRFISELADGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAQELKRAADAADEGGDDFHWHRNVFAPLKYSVAEIFDSIDLTQRIMDEQQQGVKDDIAALLNKDWRAAISSCEMLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATLGGAELGFIDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQNYFDNPWTLTHANADRLLDMRDEELALRSEEVTGELPPDLEFEEFSEIREQLAAMIEQALKIYQEQQMPLNLGAVMRDYLAQYPRARHFDVARLVVDQAVRLGVAEADFSGLPAQWQAINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: RPA12_BOVIN
Sequence: MDLAGICSSFQSDLDFCPDCGSVLPLPGVQDAVACTRCGFSINVRDFEGKVVKTSVVFNKLGTAMPLSMEEGPEFQGPVVDRRCSRCGHEGMAYHTRQMRSADEGQTVFYTCTNCKFQEKEDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal RpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CARB_METS3
Sequence: MPIDKDIKKVLIIGSGPIQIGQAAEFDYSGSQACKSLREEGIETVLVNSNPATIQTDMDMADTVYTEPLTPEIVSEIIKKENVDAILPTMGGQTGLNIATGLGDLGLLDGIKVLGSDIQTIKDVEDRDLFGHFMDKLNEPIPKCHAVESVEEAIEAVKDIGYPVIVRPAFTLGGTGGGVAYNEEELIEIATHGLDMSFINQVLIDESVLGWKEFEYEVMRDKEDTCIIVCNMENIDPMGIHTGESVVVAPAQNLNDRDSQALRDASIKIIRALGIQGGCNIQFAVNPETGEYKVIEVNPRVSRSSALASKATGYPIAKISSKIALGMTLDEIKNDITKETPASFEPAIDYVVVKIPRWPFDKFRGINREIGVQMKATGEVMAIGRTFEEAIQKAIRSLDMGHDGFEYVEYTEDDLANPTDERLFQLYSAIKDGMDLDKIQKLTNIDKFFLYKIRNIVNFENEVTEEKLNDADFLRKAKQMGCSNKRLAALSNQTEEYIRNLLNRFNIKQSYKMVDTCAAEFEAKTPYYYSTYDSGNELKSSNKKKIVILGAGPIRIGQGIEFDYCCVHSSLALKDEGIETILINNNPETVSTDYDISDKLFFEPITFEDVMGIIDQEKPDGVIVQFGGQTSINLAVPLANAGVKILGTPYESIDGVEDRELFAKLLNKLHIHQAPYGTANSFEEAREIAERITFPVLVRPSYVIGGRAMEIVYDNNELEKYMKEAVKVSPEHPILVDKFLEDAIELDVDVLCDGEEVFIAGIMEHIEEAGVHSGDSACVIPPQTIPEHILNTIREYSTKLALELDVKGLMNIQYAVKLDEEMVYIIEANPRASRTVPFVSKAIGVPLAKVATWIMTGAKLKDFNLTKEIKIDHVAVKESVFPFLKLPESDTVLGPEMKSTGESIGVDENFGMAFYKSQLAAGMDLPKEGKIFISVKEQDKKKIRPIAEKAANLGFELAATSGTADAAKGVDIEKIKKVSQGSPNIRDAILNKEIDLIINTSEGKQSAQDGYIIRRLAIELGIPYVTTLSGARAALNAIEAVQNNEITVKSLNEHIDGE
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: ATOH7_CHICK
Sequence: MKTCQSSHLDSGVESDIQCRSGSGCVVKCSTERMESAAKRRLAANARERRRMQGLNTAFDRLRKVVPQWGQDKKLSKYETLQMALSYIMALTRILAEAERYSTEREWINLHCEHFHPESYHHYTGQKVATDSDPYAQRIFSYHPEHFQIAN
What is the function of this protein?
Transcription factor that binds to DNA at the consensus sequence 5'-CAG[GC]TG-3' (By similarity).  Positively regulates the determination of retinal ganglion cell fate and formation of the optic nerve and retino-hypothalamic tract (PubMed:11124117, PubMed:15342472, PubMed:16260616).  Required for retinal circadian rhythm photoentrainment (By similarity).  Plays a role in brainstem auditory signaling and binaural processing (By similarity).  During retinal neurogenesis, activates its own transcription, as well as the transcription of CHRNB3 and BRN3 (PubMed:11172005).
What are the official names of this protein?
Transcription factor ATOH7, Atonal bHLH transcription factor 7, Helix-loop-helix protein cATH-5, cATH5, Protein atonal homolog 5, Protein atonal homolog 7.
What are the subcellular locations of this protein?
Nucleus. Perikaryon. Cell projection, axon.
Protein: HM23_CAEEL
Sequence: MDTHLPFQTLPVSTPLPVSSSSLTDVLQTIAALQACPTSCIPSTSTGMLSPNLPFSATIPRVNLFPPSQPANSLILPTIPAQPFIPNPSLLQANPSAVEALANALFATTSRRASCPEPPASSQATVTLQVPSTGSPERRRYSETNMEVLLREQLAQLMPPTSQLPGMPGCYYQHVPAAGTSGIQGSLDAALMGAVPLAMNSMAHSRRAANHRKARTIYGTTQTQQLEDMFKGQMYVVGAERENLAQRLGLSPSQVRIWFQNRRSKHRRKQQEEQQSTTLEEKSEEIGKDEEEDDEEDEDDVKVLN
What is the function of this protein?
Probable transcription factor (PubMed:11493519).  Required for differentiation of AIY interneurons, acting downstream of LIM/homeobox protein ttx-3 (PubMed:11493519).  Modulates gene expression, acting downstream of AMP kinase aak-2/AMPK signaling (PubMed:28560849).  Modulates lifespan (PubMed:28560849, PubMed:21713031).
What are the official names of this protein?
Homeobox protein ceh-23.
What is the protein family that this protein belongs to?
Belongs to the distal-less homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAB_SHELP
Sequence: MSKKLHIKTWGCQMNEYDSSKMADLLDEYQGYTLTEEAEEADVLLLNTCSIREKAQEKVFHQLGRWKTLKDKNPNLIIGVGGCVASQEGKAIKDRAQCVDLIFGPQTLHRLPEMIEQIQQGGKAVIDVSFPEIEKFDRLPEPRAEGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPVDDVILEIAQLAEQGVREVNLLGQNVNAYRGATHDDDICTFAELLRYVAAIDGIDRIRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDLILTQMKRGHMAIEYKSIIRRLRKARPDIQISSDFIVGFPGESKQDFADTMKLIEDVQFDHSFSFIYSARPGTPASDLPDDVSLDEKKERLAILQDRITQQAMRYSRQMLGTVQRILVEGPSVKNPMELRGRTENNRVVNFEADPKHIGSFVDVEIVDVFTNSLRGKFIRGEDEMDLRRDLRPSDILAKHKKDDDLGVTQFIP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_SYNE7
Sequence: MAKAVVLLSGGLDSATAAAQAIADGYEAIALSFRYGQRHVRELEAARSVAAALGINQHFFVDVNIAQWGGSSLTDAAEPLPGSGVVAGEIPSTYVPGRNTVFIALALSLAEAQQASAIYLGINAVDYSGYPDCRPDYLAAFQQLASLSSKVGVEGQAPQLVAPLIHDHKVDIVRRAVVLGVPIPATWSCYAGGAEACGRCDSCRIRDRALIEAGYPEWATAIGRSLVSLQP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RK11_PHATC
Sequence: MAKKITALIKLALPASKATPAPPVGPALGQHGVNIAAFCKEYNARTNDKAGLIIPVEISVYEDRSYTFVLKTPPASVLLANAAKIKKGSSNPNTVSVGSITKTQLEEIANIKLPDLNTTKISSAMKIVEGTARNMGISILD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPP_SULIM
Sequence: MPLYVIDKPLTLHILTQLRDKNTDQINFRKNLVRLGRILGYEIANTLDYEIVEVETPLGARTKGIDITDLNNIVIINILRAAVPLVEGLLKAFPKARQGVIGASRVEVDGKEVPKDMDVYIYYKKIPNIRAKVDNVIIADPMIATASTMLKVLEEVVRANPKRIYIVSIISSEYGANKILSKYPFIYLFTVTIDPELNNKGYILPGLGDAGDRAFG
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.