PharMolix/UniProtQA huggingface dataset:
Protein: BIOB_HERAR
Sequence: MSSQPVTFQAPVAPIVPTAWPVDDVLALFNLPFNELMFRAQTVHREHFDPSEVELATLLSIKTGGCPEDCGYCPQAARYDTGVTAQKILPLEEVLTAAREAKAHGATRFCMGAAWREPKDRDLEKVEEMVREVKAMGMETCATLGMLGEGQAEKLKNAGLDYYNHNLDTAPEFYSNVISTRDYQNRIDTLARVRNVGIKVCCGGIVGMGESRLQRAGLIAQLCNMDPYPESVPVNNLVQVEGTPLHGTDPIDPLEFVRTVAVARITMPKARVRLSAGRREMGEAIQALCFVAGANSIFYGDKLLTTGNPEALADQELLEKLGMHTRSTAIDARCDVTPS
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YAB3_ARATH
Sequence: MSSMSMSSSSAPAFPPDHFSSTDQLCYVHCSFCDTVLAVSVPPSSLFKTVTVRCGHCSNLLSVTVSMRALLLPSVSNLGHSFLPPPPPPPPPNLLEEMRSGGQNINMNMMMSHHASAHHPNEHLVMATRNGRSVDHLQEMPRPPPANRPPEKRQRVPSAYNRFIKEEIQRIKAGNPDISHREAFSAAAKNWAHFPHIHFGLMADHPPTKKANVRQQEGEDGMMGREGFYGSAANVGVAHN
What is the function of this protein?
Involved in the abaxial cell fate determination during embryogenesis and organogenesis.  Regulates the initiation of embryonic shoot apical meristem (SAM) development (PubMed:10457020, PubMed:12417699, PubMed:19837869).  Contributes to the repression of KNOX genes (STM, KNAT1/BP and KNAT2) to avoid ectopic meristems.  Binds DNA without sequence specificity (PubMed:10457020, PubMed:12417699).
What are the official names of this protein?
Axial regulator YABBY 3.
What is the protein family that this protein belongs to?
Belongs to the YABBY family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FNRL_CERS4
Sequence: MTLHEVPTILHRCGDCPIRHRAVCARCDSEELATLEQIKYYRSYQAGQTVIWSGDKMDFVASVVTGIATLTQTMEDGRRQMVGLLLPSDFVGRPGRQTVAYDVTATTDLLMCCFRRKPFEEMMQKTPHVGQRLLEMTLDELDAAREWMLLLGRKTAREKIASLLAIIARRDAALKLRESNGPMTFDLPLTREEMADYLGLTLETVSRQVSALKRDGVIALEGKRHVIVTDFARLLEEAGDDSDGGLPV
What is the function of this protein?
Anaerobic regulatory protein; transcriptional activator of hemA.  Appears to regulate other genes.
What are the official names of this protein?
Transcriptional activator protein FnrL.
Protein: ILVC_BRUSU
Sequence: MRVYYDRDADVNLIKSKKVVIVGYGSQGRAHALNLKDSGAANVRVALREGSATVQKAQADGFEVMNVADAAKWADLMMMATPDELQADIYRDHIHNNLRDGAAIAFAHGLNVHFGLIEPKKTVDVVMIAPKGPGHTVRGEYQKGGGVPCLIAIHQDASGNAHDLALSYASGVGGGRSGVIETTFKEECETDLFGEQAVLCGGVVELIRTGFEVLVEAGYAPEMAYFECLNEMKLIVDLIYEGGIANMNYSISNTAEWGEYVTGPRIITAETKAEMKRVLKDIQTGKFTSDWMQEWKAGAARFKGIRRLNDAHQIEEVGGKLRAMMPWIEKNKLVDKARN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SYFAB_XENLA
Sequence: MADNLLSEQLLQRLQDGDNKGVDTLELAAVLSVDHQQVVGAVKSLQCLGEIIEAEQRSSKKWELSSEGEEIAQVGSHEARVFQSLPKEGLLQAELMKLPFAKVGFSKAMSNKWIRLDKAAAGGPCVYRVVETIEDTVKEKLQLILKGRADDVNEKDKNELKKRKLVNEVTVKSYWVTKGSGFSTSITKQETDLTPEMIASGSWREKQFKGYNFNALGVMPECGHLHPLLKVRTQFRQIFLEMGFTEMPTNNFIESSFWNFDALFQPQQHPARDQHDTFFLQDPALATEFPMEYLERVKKVHSEGGYGSQGYKYDWSIHEAQKNILRTHTTAVSARMLYKLAHQKEFTPVKYFSIDRVFRNETLDATHLAEFHQIEGVVADRGLTLGNLMGVLKEFFHKLGITKLRFKPAYNPYTEPSMEVFSYHEGLKKWVEVGNSGLFRPELLLPMGLPGDVNVLGWGLSLERPTMIRYGIKNIRELVGHKVNLQMVYDSPICRLDAC
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit B, Phenylalanyl-tRNA synthetase alpha subunit B, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG058_VACCP
Sequence: MKYRLYSEGLSITNDLNSIIGQQSTMDTDIEIDEDDIMELLNILTELGCDVDFDENFSDIADDILESLIEQDV
What are the official names of this protein?
Protein OPG058, Protein F14, Protein F4.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG058 family.
Protein: TNNT1_MOUSE
Sequence: MSDTEEQEYEEEQAEDEEAVEEEEAPEEPEPVAEREEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELIALKDRIERRRAERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKLRILSERKKPLNIDYMGEDQLREKAQELSEWIHQLESEKFDLMEKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK
What is the function of this protein?
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin T, slow skeletal muscle, TnTs, Slow skeletal muscle troponin T, sTnT.
What is the protein family that this protein belongs to?
Belongs to the troponin T family.
Protein: VIME_SHEEP
Sequence: MSTRSVSSSSYRRMFGGPGTASRPSSTRSYVTTSTRTYSLGSALRPTTSRTLYTSSPGGVYATRSSAVRLRSGVPGVRLLQDSVDFSLADAINTEFKNTRTNEKVELQELNDRFANYIDKVRFLEQQNKILLAELEQLKGQGKSRLGHLYEEEM
What is the function of this protein?
Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.
What are the official names of this protein?
Vimentin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Nucleus matrix. Cell membrane.
Protein: DXR_PARUW
Sequence: MKHIAILGSTGSIGKNTLQVARHLKERIKVVAIAARENIDLLEAQSKEFCPDIIAVFNNAKAYELQKRLPGKTVLAGMEGLLAAASYSEADLVISAMTGTMGLQPTIEAIKAGKDVGLANKEALVSGGAIIMKLVKEKNINLLPIDSEHSAIFQCLNGEALKSVQRIILTSSGGPFRTWTQEQLETVTVEQALNHPTWSMGPKVTIDSSTLMNKGLEVIEAFWLFDVSPEQIDVIVHPQSIIHSLVEFCDGSMLAQMSEPNMIVPIQYSLTYPDRAPGLFKPFDFMKNSKLEFFEPNKKTFRCLALAYEALKCGGTLPCYMNAANEVLVERFLKGELSWKNIGIQLEKLMDQHASISVDSLETILAVDALAREEAARSKLISTK
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: GPDA_RICM5
Sequence: MNKFKNIAVYGGGSFGTSLASLAAQNCNNVTLFLRDEAIAKEILHNKTNIKYLGDIKLPAHLQATTNLDIIKDFELIIIAVPSYAFDDSIKLLKTHSISKDNTLLIATKGFARNPTALFSDRLKTLLPHSPTAFFAGPNLAKELAKNLPASASIASLDIDIANKIAYNLSAKIFTTNVSSDIVTLQVAGALKNIFAIKSGIDLARKQGENARATLIVAALKEIAILSQALGGMQKNSDILLEVGVVGDLVLTCYSLGSRNTKFGYELGISSDKKKFLQEYKELVEGREALKLVLDLIKKYNLHMPVISKVASCVIPYVIPAKAGIQHKAR
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_BACC1
Sequence: MIWVAVVITMLLFILVAKPTGIYLEKAFQGSKKLDKVFGPFEKLIFKITGVKEYNQTWKQYALSLVLLNGFMIVVVYFVFRLQGVLPLNPANIKGMEPTLAFNTAISFMADTNLQHYSGENGLSYLSQLIGITFLMFAAPATTLALVMAFIRGLAGKELGNFFVDFTRALTRVFLPIAFMAALVFVALGVPQTLDGVVTAQTIDGAKQSILRGPVASFVSIKELGNNGGGFFGANSTHPFENPGQMSNILQMMLMMLLPTALPFTYGRMVGNKKQGRILFVSLFMVFLLGFITITTSELNGNPVLNGMGIEHVQGSTEGKEVRFGTVFSSLYATVTTAAETGAVNTMHDTLTPIGGLVPLVNMMLNTVYGGVGAGFVNIIMYAIIAVFISGLMVGRTPEFLGKKIEGKEMKLIAVTILFHPLLILGFSALALSTHLGTEAISNSGFHGLTQVVYEYTSSAANNGSGFEGLADNTPFWNITTGLVMFLGRYFSLITMLAVAASLKEKTVVPETVGTFRTDNSLFGGIFIGTIVIVGALTFFPMLVLGPIAEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OM3A_RHILV
Sequence: MNIRMVLLASAAAFAASTPVLAADAIVAAEPEPVEYVRVCDAYGTGYFYIPGTETCLKIEGYIRFQVNVGDNPGGDNDSDWDAVTAVRFSSRKSDTEYGPLTGVIVMQFNADNASDQDAILDSAYLDVAGFRAGLFYSWWDDGLSGETDDIGSVVTLHNSIRYQYESGTFYAGLSVDELEDGVYQGTFTPGVIPGTTDFTADDGPNNVGVAFGIGGTAGAFSYQVTGGWDVDNEDGAIRAMGTVEIGPGTFGLAGVYSSGPNSYYSSAEWAVAAEYAIKATDKLKITPGRWHGHVPEDFDGLGDAWKVGLTVDYQIVENFYAKASVQYLDPQDGEDSTSGYFACSVRSNHLVDAPGLRIGSTTISF
What is the function of this protein?
May act as an outer membrane pore.
What are the official names of this protein?
Outer membrane protein IIIA, OMPIIIA.
What is the protein family that this protein belongs to?
Belongs to the alphaproteobacteria porin family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: END4_YERPA
Sequence: MKFVGAHVSAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVIEKFKLACEKYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDELVRCQQLGLSLLNFHPGSHLLQIDEDQCLARIAESINIALDATEGVTAVIENTAGQGSNLGFKFEHLAAIIERVEDKSRVGVCIDTCHAFAAGYDLRTEEDCEHTFAALGKIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMRDSRFDNIPLILETVNMDIWAEEIAWLKSQAEIEPSL
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: GT42_ORYSJ
Sequence: MGSRTVGWWLLAAAVVLAAAAADSGEAERAAEQHSERISGSAGDVLEDNPVGRLKVFIYDLPRKYNKKMVNKDPRCLNHMFAAEIFMHRFLLSSAVRTLNPKEADWFYTPVYTTCDLTPAGLPLPFKSPRVMRSAIQYISHKWPFWNRTDGADHFFVVPHDFGACFHYQEEKAIERGILPLLQRATLVQTFGQENHVCLKEGSITIPPYAPPQKMQAHLIPPDTPRSIFVYFRGLFYDTGNDPEGGYYARGARASLWENFKNNPLFDISTDHPPTYYEDMQRAVFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVEEKDVPKLDTILTSMPIDDILRKQRLLANPSMKQAMLFPQPAQPRDAFHQILNGLARKLPHPEGVYLQPSDKRLNWTAGPVGDLKAW
What is the function of this protein?
Involved in the synthesis of glucuronoxylan hemicellulose in secondary cell walls.
What are the official names of this protein?
Probable glucuronosyltransferase Os04g0398600.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 47 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: TAZE_ASPTN
Sequence: MTAEHDAAILPKPGGPLAVGKRATPEPGPNDVLIEVKAVALNPCDYYQRDYGMPPVPIYPAVIGGDAAGVVAKLGSSVTGGPVPGPGSRVIAFASSFYQNGSPDHGAFQKYALAQSEAVIPLPDNLSFEEGAVFPLAVLTALTAWTTIGIPLDTRYTPADKQAVLIWGASSSVGSFAVQSAKTLGFTVYATASPKHHELVKKLGADAVFDYKDSDVVSKIVDAVKKDGVYLHTAHCVVDGALQPTLDILKETKGDAFAKVAHSPVLPECHPTLDNTQITFNFPSMDEVVRTRISKLRRAVSRE
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of azaterrilone A and other azaphilones, a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities (PubMed:35398258).  The first step of the pathway begins with the non-reducing polyketide synthase tazA that assembles one acetyl-CoA starter unit, five malonyl-CoA units, and catalyzes a series of Claisen condensations, methylation, PT-mediated cyclization, and finally releases the first hexaketide precursor through the R-domain.  The tazA product then undergoes reduction on its terminal ketone and the following pyran-ring formation by yet undetermined enzyme(s).  Dehydration and enoyl reduction, possibly involving the trans-enoyl reductase tazE leads to the next intermediate.  TazD is predicted as an acetyltransferase and might catalyze the acetylation steps leading to the synthesis of azaterrilone A.  Azaterrilone A is not the final product of the taz pathway and both the highly reducing polyketide synthase tazB and the dual enzyme tazHJ catalyze late steps of the pathway, leading to the production of the 2 final stereoisomers that contain additional polyketide modification whose structures have still to be determined (Probable).
What are the official names of this protein?
Trans-enoyl reductase tazE, Azaphilone biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: TVB7_MOUSE
Sequence: MAPRLLFCLVLCFLRAEPTNAGVIQTPRHKVTGKGQEATLWCEPISGHSAVFWYRQTIVQGLEFLTYFRNQAPIDDSGMPKERFSAQMPNQSHSTLKIQSTQPQDSAVYLCASSLSTGVSYEQYFGPGTRLTVL
What are the official names of this protein?
T-cell receptor beta chain V region CTL-F3.
Protein: RECR_ALIFM
Sequence: MRTSGLLEQLMESLRCLPGVGPKSAQRMAFHLLQRNRQGGMQLADALSQAMSEIGHCSECRTFTEEDTCAICLNPKRQASGEMCIVESPADIVAVEATGQFSGRYFVLMGHLSPLDGIGPSDIGLDLLDHRLNRGDIKEVILATNPTVEGEATAHYIAELCQEHQVPASRIAHGVPMGGELELVDGTTLSHSILGRQKLY
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NDHI_DRANE
Sequence: MLPMITGFMNYGQQTLRAARYIGQGFMITLSHTNRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETNIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYEFSTYDRHELNYNQIALGRLPMSVMDDYTIRTIWNSPQTKNG
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: VNS1_EHDV2
Sequence: MERFLRKFNMNSYYANHVKMFQALSPQWTCSHLRRNCLFDGVCAKQHFEEVMNRITERNDAHAAYRLAEMAQITMLDREKVWLQCYKSFSEPYDENIAEKIQICGRELLDKYKNSDMVTKIDNMIKFDPTRIVLDDNFSAFPYLYIPVNYGQMVQPIRIMRYRQIGYCFYQPDAVDDWIAPDIYPMRRPRMEMCRQVKEAVGSCSFTGFSGPVFQIMFFPMQMLPYMENEGFAKIINRYAQMAVQAIFTSRLHRGERYVTQLFGECPAGEFPMHHMMLRRWEGNGRPQTLVQMRHTIAGNKEWQTWLLPMILVRIAVREPANFEYVRGFMQGRHKCQLCFLKNGCDRETFYHIDVRTSEIVGCSTVTQVMIGEHVDISLPVQKIKLTGTEHLGRASDHYFKYNATTGMEALIRTAIQIHRWIRGTGIWENDEWQEGIYLLARVLLRWELSTQARSIMFRLFCFVCFGYAPRKDGTVPDWKDLGAFLDIILNGTELGDDEDETGQTGIMFELSRCVMTLAYAERIKVVTFNAPECDEGAVMNIAQAMANMWDN
What are the official names of this protein?
Non-structural protein NS1, Hydrophobic tubular protein.
What is the protein family that this protein belongs to?
Belongs to the orbivirus non-structural protein NS1 family.
Protein: IDI2_AERPE
Sequence: MTGDTSARKLEHLKMIVSSKVESRESTLLEYVRIVHNPTPEVNLGDVSLEIDFCGGRLRAPLVITGMTGGHPDVEWINRELASVAEELGIAIGVGSQRAAIEDPSLARTFRAAREAAPNAFLIANLGAPQLSLGYSVREVRMAVEMIDADAIAIHLNPGQEAYQPEGDPFYRGVVGKIAEAAEAAGVPVIVKETGNGLSREAVAQLRALGVRCFDVAGLGGTNWIKIEVLRGRKAGSPLEAGPLQDFWGNPTAAALMEARTAAPDAYIIASGGVRNGLDAARAIALGADAAGVALPAIRSLLSGGRQATLKLLKAIEYQLKTAVYMVGETRVRGLWRAPIVVWGRLAEEAEARGIDPRWYTNTLRLEALVYKDVK
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBB_METAN
Sequence: MREIVHLQTGQCGNQIGAAFWQTISGEHGLDSNGVYNGTSELQLERMSVYFNEASGNKYVPRAVLVDLEPGTMDAVRAGPFGQLFRPDNFVFGQSGAGNNWAKGHYTEGAELVDNVLDVVRREAEGCDCLQGFQITHSLGGGTGAGMGTLLISKIREEFPDRMMATFSVVPSPKVSDTVVEPYNATLSVHQLVENSDETFCIDNEALYDICMRTLKLSNPSYGDLNYLVSAVMSGVTTCLRFPGQLNSDLRKLAVNMVPFPRLHFFMVGFAPLTSRGAHSFRAVSVPELTQQMFDPKNMMAASDFRNGRYLTCSAIFRGKVAMKEVEDQMRNVQNKNSSYFVEWIPNNIQTALCAIPPRGLKMSSTFIGNSTSIQELFKRVGEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAGVDEEEEEYDEEAPVEEPLE
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta chain, Beta-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: MSCL_HAEIG
Sequence: MNFIKEFREFAMRGNVVDMAIGVIIGSAFGKIVSSLVSDIFTPVLGILTGGIDFKDMKFVLAQAQGDVPAVTLNYGLFIQNVIDFIIIAFAIFMMIKVINKVRKPEEKKTAPKAETLLTEIRDLLKNK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VP2_BTV1V
Sequence: MDELGIPVYKRGFPEHLLRGYEFTIDVGTKIESVGGRHDVTKIPEMNAYDIKQESIRTALWYNPIRNDGIVLPRVLDITLRGYDERRAVVESTRHKSFHTNDQWVQWMMKDSMDAQPLKVGLDDQSRNVAHSLHNCVVKIDSKKADTMSYHVEPIEDASKGCLHTRTMMWNHLVRIETFHTAQEVHILFKPTYDIVVHAERRDRSQPFRPGDQTLINFGRGQKVHMNHNSYDKMVEGLTHLVMRGKMPEVIRDDIASLDEICNRWIQSRHDPGEVKAYELCKILSTIGRKVLDREKEPEDEANLSIRFQEAIDNKFRQHDPERLKIFEHGNQRRDEDRFYILLMIAASDTFNTRVWWSNPYPCLRGTLIASETKLGDVYSMMRSWYDWSVRPTYTPYEKTREQEEYIYGRVNLFDFVAEPGIKIVHWEYRLNHSTREITYAQGNPCDLYPEDDDVIVTKFDDVAYGQMINEMINGGWNQEQFKMHKILKTEGNVLTIDFEKDAKLTTNEGVTMPEYFNKWIIAPMFNANVRIKHEEIAQRQSDDPMVKRTLSPITADPIELQRLTLARFYDIRPALRGQALSRQQAQSTYDEEISKKAGYAEVLKRRGIVQIPKKPCPTVTAQYTLERYALFIINYLQQHVARDCDEEAIYEHPKADHELEIFGESIVDISQVIVLVFDLIFERRRRVRDVYESRYIIARIREMRGKEKLNVIAEFFPTYGSLLNGLSGATVVQDIMYLNFLPLYFLVGDNMIYSHRQWSIPLLLYTHEVMVIPLEVGSYNDRCGLIAYLEYMVFFPSKAIRLSKLNEAHAKIAREMLKYYANTTVYDGGDNSNVVTTKQLLYETYLASLCGGFLDGIVWYLPITHPNKCIVAIEVSDERVPASVRAGRIRLRFPLSARHLKGVVIIQVDLGGRFTVYSEGIVSHRVCKKNLLKYMCDIILLKFSGHVFGNDEMLTKLLNV
What is the function of this protein?
The VP2 protein is one of the two proteins (with VP5) which constitute the virus particle outer capsid.  It is the major target of the host immunogenic response.  Responsible for viral attachment to target host cell, probably by binding to sialic acid.  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Outer capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP2 family.
What are the subcellular locations of this protein?
Virion.
Protein: TSGAD_HALVD
Sequence: MLDEESSIQRRDVLSALGAAGVTTLAGCTGGDTGDTDDTEASETTASEGTTSGTTTGDVETTDGGGPSEGETVNAAWVYISEIGDLGWSWAHDQARQAVDEQYDWLETEYTEAVAPSDSERVFEQYAQGDVDVIFGTTFGYQDPMYAVAEDYPDTVFEHATGYRTRENMGRYMGRIYEPRYLAGQATGMVTENNTIGYVAAFPIPEVVRSINAMALGARSVNPEATFKVRWVNAWFDPPTAREAANALIDEGCDVIAQEQDSPAAVRAASDAGVWTSGYNAPMGQFGGENYLISPIWDWTEFYGPTLESLHEGSWEADAFWGGMETGVPMLDEWGPNVSQEVKDQVAATEEQILNDELDVWAGSAFEGESDEFLFQEMSSFVEGVEGEVPS
What is the function of this protein?
Part of an ABC transporter complex involved in glucose import.
What are the official names of this protein?
Putative ABC transporter glucose-binding protein TsgA13.
What is the protein family that this protein belongs to?
Belongs to the BMP lipoprotein family.
Protein: HEMA_CVBLU
Sequence: MFLLPRFVLVSCIIGSLGFDNPPTNVVSHLNGDWFLFGDSRSDCNHVVTTNPRNYSYMDLNPALCGSGKISAKAGNSIFRSFHFTDFYNYTGEGQQIIFYEGVNFTPYHAFKCITSGSNDIWMQNKGLFYTQVYKNMAVYRSLTFVNVPYVYNGSAQSTALCKSGSLVLNNPAYIAREANFGDYYYKVEADFYLSGCDEYIVPLCIFNGKFLSNTKYYDDSQYYFNKDTGVIYGLNSTETITTGFDFNCHYLVLPSGNYLAISNELLLTVPTKAICLNKRKDFTPVQVVDSRWNNARQSDNMTAVACQPPYCYFRNSTTNYVGVYDINHGDAGFTSILSGLLYDSPCFSQQGVFRYDNVSSVWPLYPYGRCPTAADINTPDVPICVYDPLPIILLGILLGVAVIIIVVLLLYFMVDNGTRLHDA
What is the function of this protein?
Structural protein that makes short spikes at the surface of the virus.  Contains receptor binding and receptor-destroying activities.  Mediates de-O-acetylation of N-acetyl-4-O-acetylneuraminic acid, which is probably the receptor determinant recognized by the virus on the surface of erythrocytes and susceptible cells.  This receptor-destroying activity is important for virus release as it probably helps preventing self-aggregation and ensures the efficient spread of the progeny virus from cell to cell.  May serve as a secondary viral attachment protein for initiating infection, the spike protein being the major one.  May become a target for both the humoral and the cellular branches of the immune system.
What are the official names of this protein?
Hemagglutinin-esterase, HE protein, E3 glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=In infected cells becomes incorporated into the envelope of virions during virus assembly at the endoplasmic reticulum and cis Golgi. However, some may escape incorporation into virions and subsequently migrate to the cell surface.
Protein: DNAG_STAAU
Sequence: MRIDQSIINEIKDKTDILDLVSEYVKLEKRGRNYIGLCPFHDEKTPSFTVSEDKQICHCFGCKKGGNVFQFTQEIKDISFVEAVKELGDRVNVAVDIEATQSNSNVQIASDDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGFAPDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVGYSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDTAGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVFVIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKELSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEIQFNQAPANYYPEDEYGGYDEYGGYIEPEPIGMAQFDNLSRREKAERAFLKHLMRDKDTFLNYYESVDKDNFTNQHFKYVFEVLHDFYAENDQYNISDAVQYVNSNELRETLISLEQYNLNGEPYENEIDDYVNVINEKGQETIESLNHKLREATRIGDVELQKYYLQQIVAKNKERM
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
What are the official names of this protein?
DNA primase.
What is the protein family that this protein belongs to?
Belongs to the DnaG primase family.
Protein: VP34_BPAPS
Sequence: MAAPVSGRRMAYRASLALTMYCCSTGERLRFAMAPSPSARLINATRLVSIFFPNLCIESMESFRRRANPAAFFDPSLALSMILCACGRLIGLMPSPAMGWFIFPVSSLPSV
What are the official names of this protein?
Putative protein p34.