PharMolix/UniProtQA huggingface dataset:
Protein: SYT_CUPNH
Sequence: MIAITLPDGSRREFPGPVTVAEVAQGIGAGLAKAALAGKVDGQLVDTSYRIDRDAELAIVTDKDADGVDVIRHSTAHLLAYAVKELYPEAQVTIGPVIENGFYYDFAYKRPFTPEDLAAIEKKMTELARKDEKVVREVWNRDEAVALFESMGEKYKAEIIASIPADQEIGLYREGSFVDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDANNEMLQRIYGTAWARKEDQEAYLHMLEEAEKRDHRKLGKTLDLFHLQEEAPGMVFWHPKGWQVWQAVEQYMRGRLTDAGYDEVRTPQVMDRSLWEKSGHWQNYKENMFVTESEKRDYAIKPMNCPGHVQIFNHGLRSYRDLPLRLAEFGACHRNEPSGALHGLMRVRGFVQDDAHIFCTEEQIVAEAKAFNELAFSVYDDFGFKDVKVKLSLRPDQRAGSDEIWDHAEEGLRLALRACGVDWEELPGEGAFYGPKVEYHIKDAIGRSWQCGTLQLDLVLPERLDAEYVSEDNSRKRPVMLHRAILGSFERFLGILLENHAGALPAWLAPEQVVVMNIADSQAEYAESVVQLLQKQGFRAKADLRNEKITYKIREHSLQKVPYLLVVGDKERDASQVAVRARGNVDLGVMPVSAFVERLKNDVASKA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_AROAE
Sequence: MARNAPAFWQTRSLAARLLLPLSGLFLLLAAVRRQLFRLGIRRAVRLPVPVVVVGNIAVGGSGKTPVVEWLVARLRDAGFTPGIVSRGYGGKAPGAVIVPPHGDVRLFGDEPVLLARLTACPVAVGADRPAAARALLQAYPGCDVIVADDGLQHYPLARDVEIAVVDERTLGNRWLLPAGPLREGPGRLRDVDIIIAHGALSPALSSLLDGRPVFAMHLEGSEFRRLDGAGCRNAEAFRGVRVHAVAGIGRPERFFAQLTRMGLEVVPHPFPDHHPFTAADLDFAPGEPKILTSKDAVKCASFASADTWEFPVKAHIAAGAAERILEKLTHGRPTA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RL23_THEP3
Sequence: MEARDIIIRPVITEKSMNLMSERKYTFIVDKRANKIQIKKAVEDIFGVKVDKVYTMNYKGKPKRMGKYEGRTEAYKKAIVKLTPDSKGIEFFEGLQA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RS3_PROM2
Sequence: MGHKIHPSGLRLGITQEHRSKWFATSKTYPILLQEDFKIRTFIEKKYGAAGISDVLIARKADQLELELKTARPGVIVGRQGSGIEELRSGIQKTIGDRTRQVRINVVEVERVDADAFLLAEYIAQQLEKRVAFRRTIRMALQRAQRAGVLGLKIQVGGRLNGAEIARTEWTREGRVPLHTLRAEIDYATREANTTYGVLGIKVWVFKGEVLPKEEQTIPVGANPKRKASRRPQQFEDRSNENS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: NRDR_AERHH
Sequence: MHCPFCSAVDTKVIDSRLVAEGHQVRRRRECLLCHERFTTFEMAELVMPRVIKSNGSREPFNEDKLRAGILRALEKRPVSMEAIEKAVNHIKSRLRATGEREVASQLVGNLVMDELKSLDKVAYIRFASVYRSFEDIREFGEEIAKLEK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: AROE_BACCR
Sequence: MKQLYGVIGNPIGHSLSPVMHNDAFEHLNMDAHYHAFLVEEELLGEAVRGLKALGISGFNVTTPHKVAIMEYLDEIDPLARKIGAVNTVVHKDGRLIGYNTDGIGFVRALQSISNEPLQGKRILLLGSGGASRAIYFSLADVGVKEIDVANRTVDKAKELIAARTADVNSVALSLEKATEEQGNYDIIIQTTTIGMHPHVEHTPLQICSLKKGTIVSDIIYNPFETKILCEAKEQGAIIQNGIDMFVYQGALAFEMWTGRTPNIERMKQLVIEKLGG
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: IF43A_SALSA
Sequence: MDDNLQLGDSGVVKNVAKLGRRARLAAEQTSSLEESRHVRKSSSSTSMGEVPPPKPARRQGGWAEETSGSAKSGRRPAVVEDVEDRRLRPQTPQGSDDEGDIPVIPDLDEVQEEDLTMQVAAPPSIQVNRVMTYRDLDNDLMKYSAFQTLDGEIDLKLLTKVLAPEQEVREEDVGWDWDRLFTEVSSELLTEWDQGEKEEQVPLPVL
What is the function of this protein?
Component of IFT complex A (IFT-A) involved in retrograde ciliary transport along microtubules from the ciliary tip to the base.
What are the official names of this protein?
Intraflagellar transport protein 43 homolog A.
What is the protein family that this protein belongs to?
Belongs to the IFT43 family.
Protein: S27A6_MOUSE
Sequence: MLLSWLTGLGAGLLSLHFLQKLLFPYFWDDFWYLLKVVRYGIQMEMYKLRGELVTVLDKFLSHTRKQPRKAFIIYEGDVYTYEDVDKRSNRIAHALLNHSSLKRGDVVALLMSNEPDFVHVWFGLAKLGCVVAFLNSNLRFDSLLHCINTCEPTAVVVGGDLLGSIEEILPSLPKHVRVWGMKDSVPEGIDSLQEKLSLASDEPVPPSHHVTSSLKSTCLYIFTSGTTGLPKAAVISQLQVLKGSVGLWAFGCTADDIIYITLPLYHSSGSLLGIGGCVELGATCVLKKKFSASQFWNDCKKYNVTVFQYIGELCRYLCKQPQREGEKDHRVRLAVGNGLSSDVWRQFLDRFGNIKMCELYGATEGNIVFMNHTGKIGSVGRANFFYSLFFSFELIKYDFQKDEPWRNGQGWCSCVRKGEPGLLISRVNKKNPFFGYAGSDTHTKSKLLFDVFRKGDVYFNTGDLMFQDQENFVYFWDRLGDTFRWKGENVATTEVADVLGRLDFIQEANVYGVRVPGYEGKAGMTSVILKPNKSLDLEKMYNQVVTSLPAYACPLFLRIQDKMETTGTFKLKKLQLVEEGFDPLKISDPLYFMDNLKKSYVPLTEEIYNQIMSEEVKL
What is the function of this protein?
Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport at the plasma membrane (By similarity).  Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates (PubMed:15699031).  Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation such as the heart (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein 6, FATP-6, Fatty acid transport protein 6, Arachidonate--CoA ligase, Fatty-acid-coenzyme A ligase, very long-chain 2, Long-chain-fatty-acid--CoA ligase, Solute carrier family 27 member 6, Very long-chain acyl-CoA synthetase homolog 1, VLACS2, VLCSH1, mVLCS-H1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=In heart is exclusively located on the sarcolemma in areas juxtaposed with small blood vessels where it colocalizes CD36.
Protein: SYC_RHOP5
Sequence: MELRLYDTLSREKRTFTPLDPSNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHVYGEAHVKYVRNITDVDDKINDRAARDFPGLPLNEAIRKVTEQTEKQFHDDVDALGCLRPTVEPRATEHIGEMRDIIDRLIAGGFAYVAADHVLFSPQAMNAKDGVLPRYGALANRSLDEMIAGARVDVAPYKRDATDFVLWKPSKPGEPSWPSPGGIAVQGRPGWHIECSAMSWKHLGERFDIHGGGIDLVFPHHENEVAQSCCAFHTERMAETWMHNGFLQVEGEKMSKSLGNFVTIRELLATDKFGGKRWDGAVLRLAMLKTHYRSPIDWTVEALHEAEKAIYDWSEFTKDATPAPCDEVIDALADDLNTPKMIAELHGLRRVGKPAELLGALQLLGIGRVFRQTIEIDVNAQALIEARTAARARKDFKESDRIRDELAAMGVVLKDGKDADGKPVTTWEIAR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AATM_HORSE
Sequence: SSWWAHVEMGPPDPILGVTEAYKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKNLDKEYLPIGGLAEFCKASAELALGENSEALKSGRYVTVQSISGTGALRIGANFLQRFFKFSRDVFLPKPSWGNHTPIFRDAGLQLHAYRYYDPKTCGFDVTGALEDISKIPQQSIILLHACAHNPTGVDPRPEQWKEIATLVKKNNLFAFFDMAYQGFASGDGNKDAWAVRYFIEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPLYSNPPLNGARIASTILTSPDLRKQWLQEVKGMADRIISMRTQLVSNLKKEGSSHSWQHIADQIGMFCFTGLKPEQVERLTKEFSIYMTKDGRISVAGVTSGNVGYLAHAIHQVTK
What is the function of this protein?
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA).  As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance.  Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism.  Facilitates cellular uptake of long-chain free fatty acids.
What are the official names of this protein?
Aspartate aminotransferase, mitochondrial, mAspAT, Fatty acid-binding protein, FABP-1, Glutamate oxaloacetate transaminase 2, Kynurenine aminotransferase 4, Kynurenine aminotransferase IV, Kynurenine--oxoglutarate transaminase 4, Kynurenine--oxoglutarate transaminase IV, Plasma membrane-associated fatty acid-binding protein, FABPpm, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cell membrane.
Protein: ADD_CLOBM
Sequence: MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIHLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIGKGVVAIDLCAGEEPHFPGKYIEVLKLAKECGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNIPLEVCPTSNLHTKAFESYETHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIGDYKILYLNAVEASFASSETKEVLKSYVKEITA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: LSPA_SALPA
Sequence: MSKPLCSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGICVILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICIGAALIVLEGFLPKPTAKEQA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPB_SYNJB
Sequence: MTSASFAFSPRVLDPLDPQVRPDPQGRFGPFGGRFVPETLMSALTELEEAFEHHWRDPDFRAEFHNLLRDFVGRPSPLYFAQRLTEYYGGPQIYLKREDLNHTGAHKINNALGQVLLAVRMGKRRIIAETGAGQHGVATATVCARFGLECVIYMGALDMERQAPNVQRMRLLGAEVRGVESGTRTLKDALSEAIRDWVTNVETTHYVIGTVAGPHPYPKLVRAFHDVIGQETRQQCQEKWGGLPDVLLACVGGGSNALGLFNEFVRDPQVRLIGIEAAGEGLHTPRHAATLNRGRIGVLHGAMSYLLQDEEGQVQEAHSISAGLDYPGVGPEHSYLKEIGRAEYYAVTDDEAVEALLLLSRLEGIIPALETAHALAYLKTLAPQQGLRPANAIGPQQRVVVNCSGRGDKDLNTVFKYLQQRGRSF
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PYRF_METJA
Sequence: MPKLMLALDVLDRDRALKIVEDVKDYVDAIKVGYPLVLSTGTEIIKEIKKLCNKEVIADFKVADIPATNEKIAKITLKYADGIIVHGFVGEDSVKAVQDVAKKLNKKVIMVTEMSHPGAVQFLQPIADKLSEMAKKLKVDAIVAPSTRPERLKEIKEIAELPVITPGVGAQGGKIEDILNILDENDYVIVGRAIYQSQNPKEEAKKYKEMLNK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NGB_BOVIN
Sequence: MELPEPELIRQSWREVSRSPLEHGTVLFARLFDLEPDLLPLFQYNCRQFSSPEDCLSSPEFLDHIRKVMLVIDAAVTNVEDLSSLEEYLAGLGRKHRAVGVKLSSFSTVGESLLYMLEKCLGPAFTPATRAAWSQLYGAVVQAMSRGWGGE
What is the function of this protein?
Involved in oxygen transport in the brain.  Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom.  Not capable of penetrating cell membranes (By similarity).
What are the official names of this protein?
Neuroglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Perikaryon.
Protein: ANT_BPP1
Sequence: MKKPLVTRNEIAEAIALHTACMPTREIPGAIANYFMITRRFYTRTDKAVINRLLIAEIRDYLIEQGRLRYATVAAEIRKEAHRMTGNNLNVEKTAPVTSATPAPAVNIIPNTGDTIDSQTLLKMVNEARKLCGEPEVRNNKFIEKILDELEGEFYTKSAKSHGTRAGRSFEVITMTYKQALRVAARESKAVRRSLIDKLEELQQANSPAPSIPQTLPEALRLAAELAEQKMQLEQQLVAAAPKVDFADRVSVANGILIGNFAKVVGLKQNALFSWLRQNGILMAFGARKNVPRQQYINAGYFTVKEVVLDDENGYQIRLTPN
What is the function of this protein?
Antagonist of the C1 repressor or repressor bypass function.
What are the official names of this protein?
Antirepressor protein 1, ant1, Repressor bypass protein B, rebB.
Protein: RNH3_BACLD
Sequence: MSHSVLKVPPSVIERMQSHYGPDITSLSVQGAVFQAKPQGCTITAYRSGKVLFQGKNAEKEAERWTADAETPAPKKPASKKSIPSVYQPPEGIGSMSVIGSDEVGTGDYFGPITVACVYADKAKLPLLKELGVKDSKNLKDPQIVQIARDLIKTVPYSLLVLRNEKYNEMQEKGMSQGKMKALLHNQAIGNLLKKLDGTRPEAILIDQFAEPAVYFKHLAGKTAVKERTYFSTKAEGIHLSVAAASIIARYSFLMEMDKLSKQAGITLPKGAGPLVDEAGAKLIKKHGEDALRVFTKLHFANTQKAKRIASKR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_MESH2
Sequence: MPKYEIMTILDPKAEMAIIDNLLKTVFGDNSTEKLRKLETTNLAYPIRKSKIAQYFLVDLNAPTNLIEEFVRRANITREIWRYLIVNLDSEKGLNKKPKIRERNRKYTPRRDRFEKPNFRGNPKSRFDQQDQQATKNQQNFQQNQQNQTSQYRENSRQNQDDFQQVSSNQQNFGQNQQNQSGYHRENNRQNQENIHQNSKNHQNQTSQTQRNRRQYQPIKNPKFNQKEKENYNNKKPQSSN
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MYOZ2_MOUSE
Sequence: MLSHSAMVKQRKQQASAITKEIHGHDVDGMDLGKKVSIPRDIMIEELSHFSNRGARLFKMRQRRSDKYTFENFQYESRAQINHNIAMQNGRVDGSNLEGGSQQGPSTPPNTPDPRSPPNPENIAPGYSGPLKEIPPERFNTTAVPKYYRSPWEQAIGSDPELLEALYPKLFKPEGKAELRDYRSFNRVATPFGGFEKASKMVKFKVPDFELLLLTDPRFLAFANPLSGRRCFNRAPKGWVSENIPVVITTEPTEDATVPESDDL
What is the function of this protein?
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere.  Plays an important role in the modulation of calcineurin signaling.  May play a role in myofibrillogenesis.
What are the official names of this protein?
Myozenin-2, Calsarcin-1, FATZ-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the myozenin family.
Protein: MAEA_DANRE
Sequence: MAVQETAAQLSMALKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSSFPVVDTVVSLLDGVVEKLSALKRKAAESIQAEDESAKLCKRRIEHLKEHSSDQPASVNVWKKKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERQETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRMDAVRHARKHFSQAEGGQLDEVRQVMGMLAFPSDTHISPYKDLLDPARWKMLIQQFRYDNYRLHQLGNNSVFTITLQAGLSAIKTPQCYKEDGTSKNPDCPVCSKSLNKLAQPLPMAHCANSRLVCKISGEVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVICPRTKEVFNFSQAEKVYIM
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex.  MAEA is required for normal cell proliferation.  The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity).  Plays a role in erythroblast maturation and in the development of mature macrophages (By similarity).  Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis (By similarity).  Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis.  Associates with F-actin to regulate actin distribution in erythroblasts and macrophages (By similarity).  May contribute to nuclear architecture and cells division events (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein transferase MAEA, Macrophage erythroblast attacher.
What are the subcellular locations of this protein?
Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Note=Migration from nuclear matrix in immature macrophages to cell surface in mature ones.
Protein: PRP19_MOUSE
Sequence: MSLICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDIKVAHPIRPKPPSATSIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAACRVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDTNKILTGGADKNVVVFDKSTEQILATLKGHTKKVTSVVFHPSQELVFSASPDATIRIWSVPNTSCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTDVQIYICKQWTEILHFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL
What is the function of this protein?
Forced expression leads to suppression of neuronal differentiation, and on the contrary to stimulation of astroglial cell differentiation in retinoic acid-primed P19 cells (PubMed:16352598).
What are the official names of this protein?
Pre-mRNA-processing factor 19, Nuclear matrix protein 200, PRP19/PSO4 homolog, RING-type E3 ubiquitin transferase PRP19, Senescence evasion factor.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRP19 family.
What are the subcellular locations of this protein?
[Isoform 1]: Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Lipid droplet. Note=Nucleoplasmic in interphase cells. Irregularly distributed in anaphase cells. In prophase cells, uniformly distributed, but not associated with condensing chromosomes. Found in extrachromosomal regions in metaphase cells. Mainly localized to the mitotic spindle apparatus when chromosomes segregate during anaphase. When nuclei reform during late telophase, uniformly distributed in daughter cells and displays no preferred association with decondensing chromatin. Recruited on damaged DNA at sites of double-strand break (By similarity). SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus.
Protein: UBID_NEIG2
Sequence: MKYKDLRDFIAMLEQQGKLKRVAHPVSPHLEMTEIADRVLRAEGPALLFENPVKPDGTRYDYPVLANLFGTPERVAMGMGADSVSKLREIGQTLAYLKEPEPPKGIKDAFSKLPLLKDIWSMAPNVVKNAPCQEIVWEGEDVDLYQLPIQHCWPEDVAPLVTWGLTVTRGPHKKRQNLGIYRQQLIGKNKLVMRWLSHRGGALDYQEFRKLNPDTPYPVAVVLGCDPSTILGAVTPVPDTLSEYQFAGLLRGSRTELVKCIGSDLQVPARAEIVLEGVIHPNETALEGPYGDHTGYYNEQGHFPVFTVERITMRENPIYHSTYTGKPPDEPAVLGVALNEVFVPLLQKQFSEITDFYLPPEGCSYRMAVVSMKKQYAGHAKRVMTGCWSFLRQFMYTKFIIVVDDDVNVRDWKEVIWAVTTRMDPVRDTVLVENTPIDYLDFASPVSGLGGKMGLDATSKWPGETDREWGRVIKKDPAVTVKIDGIWGKLGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CHIT_PETHY
Sequence: MKFWGSVLALSFVVFLFLTGTLAQNVGSIVTSDLFDQMLKNRNDARCFAVRFYTYDAFIAAANSFPGFGTTGDDTARKKEIAAFFGQTSHETTGGTLSPDGPYAGGYCFLREGNQMGNGYYGRGPIQLTGQSNYDLAGKAIEQDLVNNPDLVATDATVSFKTAIWFWMTPQGNKPSCHDVITGRWTPSAADTSANRVPGYGVITNIINGGIECGKGQNARVEDRIGYYRRNVSIMNVAPGDNLDCYNQRNFAEV
What is the function of this protein?
Defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Acidic endochitinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class II subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Extracellular fluid from leaves.
Protein: SOR_METJA
Sequence: MTHYCGINRMKEGTDFEKKHTPFIECKDRVKANDYFEVKISTGIPHPMEDNHFIHWIELYMGDLYLARVDFTQFMKPEVKLMVKAPSKEHEKFILRALMRCNLHGVWEYEKEILLE
What is the function of this protein?
Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide.
What are the official names of this protein?
Putative superoxide reductase, SOR.
What is the protein family that this protein belongs to?
Belongs to the desulfoferrodoxin family.
Protein: MNMG_DEIGD
Sequence: MRGWNVMVIGGGHAGLEAAWAAAKFARVAVLVSNPATVGRMPCNPAVGGPGKSQLVFEVQALGGLMGRLADDTAIHTRVLNASKGPAVQSLRVQNERDAYAERAQEILLGHSGIDVVRGEAADLEPDGCGGWFVVTTDGRRFHARSVVVAAGTFMRGVTWYGRYSRPEGRQGEPPSRFLSAPLARAGHRLKRYKTGTPPRVRADSVRFADLLEIPADPQPRGFTGRPGPRAAESPTWQTHTTPETHRLIQENLHESPMYAGDIAGLGPRYCPSIEDKVVRFAHHDRHLLFVEPDGVQTSEVYLQGFSSSLPPALQDRLVRSLPGFEAAVIQRYAYAVEYDVVDSTELTLNLESRLLPGIFTAGQINGTSGYEEAAAQGLVAGTAAARRALELEELQISRETSYLGVLLDDLVLKGSDEPYRMMTSRVEHRLIVRQDNADERLTELGVKLGLVDEDTQRAVQAKYRRVAEGIRALQMQRVQGQTGDAWLRRPEFALEDVEALGFKLPALSPEEREAVAIRVKYAGYIERAERQLAAEDRARELSLRGVAFGEIASLSNEAREKLERVRPLTVAQAAGIPGVRHADISALLVHLRRTGNVSRET
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR38_PLAVT
Sequence: MHLIYIVMAATATTLHASSSAILDPSDVKIMTKNVESRIGNDAAFAAGRFLRGAYEDVHREEERMFGLKQNQHSFIKPSQAQDAAAIDALNIAKEALESTRNTKDHPHATATAGDQSLNPLIAAYPLRASPNAGVPQQHLGVALGSVHPHTSRST
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 38.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: METK_ACIAD
Sequence: MREYAVFTSESVSEGHPDKMADQISDAILDAILKEDPYARVACETLVKTGAVVLAGEITTTANVDFEAIVRQTVNGIGYHHSDLGFDGSTCAIINMIGKQSPEIAQGVDRQKPEDQGAGDQGLMFGYASRETDVLMPAPISYAHRLMERQAELRRSGALPWLRPDAKSQVTFAYENGMPVRLDAVVLSTQHDPEISQAQLKEAVIEEIVKPVIPSEMFHAGTKFHINPTGMFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADKCEIQVSYAIGVAEPTSISINTFNTAKVDEELIIALVREHFDLRPYGITRMLDLLQPMYKQTAAYGHFGREGSDTAFTWEKTDKVEVLKDAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_ORITI
Sequence: MNMEYTLSILKPDVIKRNIIGKVNTYIENSGLKIIAQKTLLLTKVQAENFYIIHKDRAYYQSLVQNMTSGPVVVQVLYGLNAVKKYREIIGATNPCDAKKGTIRGDIAKSIDENTVHGSDSLENADIEIKFFFALIEYAYL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.