PharMolix/UniProtQA huggingface dataset:
Protein: MEND_CORGB
Sequence: MSSTPAQDLARAVIDSLAPHVTDVVLCPGSRNSPLSLELLARQDLRVHVRIDERSASFLALSLARTQARPVAVVMTSGTAVANCLPAVAEAAHAHIPLIVLSADRPAHLVGTGASQTINQTGIFGDLAPTVGITELDQVAQIAESLAQRASQIPRHFNLALDVPLVAPELPELHGEAVGASWTHRWINHGEVTVDLGEHTLVIAGDEAWEVEGLEDVPTIAEPTAPKPYNPVHPLAAEILLKEQVSAEGYVVNTRPDHVIVVGHPTLHRGVLKLMSDPEIKLTVLSRTDIITDPGRHADQVGSTVKVTGTQEKQWLKICSAASELSADGVRDVLDNQEFGFTGLHVAAAVADTLGTGDTLFATASNPIRDLSLVGMPFDGVDTFSPRGVAGIDGSVAQAIGTALAVQSRHPDEIRAPRTVALLGDLSFLHDIGGLLIGPDEPRPENLTIVVANDNGGGIFELLETGADGLRPNFERAFGTPHDASIADLCAGYGIEHQAVDNLQDLIIALVDTTEVSGFTVIEASTVRDTRRAQQQALMTKVR
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: HIS4_NATPD
Sequence: MFPSFEVIPAVDMQDGQVVQLVGGERGTETEYGDPVAAAQRWVDAGAETLHLVDLDGAFEGERANADAVEAVLEATDVSVQLGGGIRTVDDADSLLSMGVDRVILGTAAVENPDIVGEINDRHPGSVVVSLDAKDGEVVVSGWTESTGLDPAEAAARYEAEGAGGVLFTDVDVEGQLSGVRADEIARVVDAVDIPVIASGGVSTLSDIEALKDAGAAATVVGTALYEGEFTLEEAAAVV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SA1_NAJNA
Sequence: LKCNKLIPLAYKTCPAGKNLCYKMYMVSNKTVPVKRGCIDVCPKNSLVLKYECCNTDRCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 1, Cobramine-A, Cytotoxin I, Cytotoxin XI, Cytotoxin-like basic protein, CLBP.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: Y295_ALISL
Sequence: MIIPWQDIAPDTLENLISEFVLREGTDYGEMECSHQDKIEQVKLLLKNGDAMVVFSELHETVDIQTKARFNPNMTNHDFE
What are the official names of this protein?
UPF0270 protein VSAL_I0295.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: GLL4_CHICK
Sequence: MKILCFFIVLLFVAVHGAVGFSRSPRYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL
What is the function of this protein?
Has bactericidal activity.  Potent activity against S. typhimurium and S. entiriditis.
What are the official names of this protein?
Gallinacin-4, Gal-4, Beta-defensin 4, Gallinacin-7, Gal-7.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule.
Protein: ACCD_RHIL3
Sequence: MNWITNYVRPRINSMLGRREVPENLWIKCPETGEMVFHKDLEGNKWVIPASGYHMKMPAKARLADLFDNGEFESLPQPKVAQDPLKFRDSKKYSDRLRDSRLKTEQEDTILAGVGKVQGLKLVAVVHEFNFIGGSLGMAAGEAIVKAFERATAEKCPLVMFPASGGARMQEGILSLMQLPRTTVAVDMLKESGQPYIVVLTNPTTGGVTASYAMLGDIHLAEPGAEIGFAGKRVIEQTLREKLPEGFQTAEYLLEHGMVDMVVKRHDIPETLARLLKILTKKPVSAANDMNGGAIALAASA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDTA_RICTY
Sequence: MMLLYYILSFILLPVYFIIIFIRLLIGKEDIRRIQERFAIGKQRQNSLLDLQMSVNQEGFKVDTEHKATSYVYIHRNASLMYKLSLERSYAQSLVWIHAASVGEVMTSLTLIHNICKLAPNVRFLITSWTNTSAKILSTKLPKIATHQFLPIDNVIFTRKFLSNWKPDLGIFIESELWPCIINEGAKHCKLLLVNARISNKSFKTWLKRKKFFQLIIKNFSKIIVQSECDLQKFNALGISDAMNLGNIKFANEKLLVNQEKLSKLSLHLDNRRVVVFASTHPEDEEVILPIINNLKEQFVDCYIILIPRHPERVKSILNNCKCHNLLATAKSQNDLPVLSDDIYIVDRFGEMGLFFSVATISFIGGSFKQGGHNILEAAYFSNCIIFGPDMSKNTDIAKGILQNNAAIQIKNGEDLLNTLKSLLNANNALKLKAYRENALKFVEHNQKILDEYLHVIKPFLP
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid transferase, Kdo transferase, Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: RL31_PYRFU
Sequence: MAIKAGEEVIFTVPIKKIKKIVPRWKRAPRAVKFVREFVARHAKAQEVIIDPKVNEKIWERGIEKPPSKLRVKVKVEEEKREGEETVRIAYVTLA
What are the official names of this protein?
50S ribosomal protein L31e, Large ribosomal subunit protein eL31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: CYB_CYRMO
Sequence: MAPNIRKSHPLMKIINNSLIDLPTPSNISAWWNFGSLLAVCLATQIITGLLLAAHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGIYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAVPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFIIAGITIIHLAFLHESGSNNPLGISSNSDKIPFHPYYSLKDILGLALMITPLLTLALFSPNLLGDPENFTPANPLTTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVFILFLIPLLHKSKQRTMTFRPLSQLLFWLLAANLFILTWIGSQPVEHPFIIIGQLASLSYFTTLLILFPIVGTLENKMLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: UBIE_FRATF
Sequence: MSKENKTTDFGFTQVPWEEKQKKVAGVFHSVAAKYDLMNDLMSFGIHRIWKKQTIAKSGVRKGDNVLDLAGGTGDLAYKFCQMVGQQGKVILSDINSSMLEVGKEKLTNKGCVGNIEYVQANAECLPFPDNYFDCITISFGLRNVTDKDKALASMCRVLKPGGRLLVLEFSKPIIPLLSKVYDEYSFKALPFLGKIITQDAESYKYLAESICKHPDQQTLKQMMYDAGFDNVEYQNMTGGIVALHIGYKY
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: EVAS_EMEVA
Sequence: MEFKYSTLIDPEMYETEGLCDGIPVRYHNNPELEEIDCLRCHEHWRENVGPLGVYKGGLADQWNGISIAIPEALPDRLGVVSYASEFAFVHDDVIDIAQHGNEQNDDLRVGFEQMIDAGAIKYSTSGKRALQSYIAKRMLSIDRERAIISLRAWLEFIEKTGRQEERRFNNEKEFLKYRIYDVGMLFWYGLLTFAQKITIPENELTTCHELAIPAYRHMALLNDLVSWEKERASSIALGKDYCINFIFVAMEESGISEDEAKERCREEIKLATVDYLRVFDEAKDRIDLSHDTMLYLESLLYSMSGNVVWGLQSPRYYTDAKFSQRQLDWIKNGLPLEVRLEDRVFGLSPSEDRVTHQAVIENGLPESGLGKNGNSSNGVDVNKALLSAVLHEHLKGHAVFKMSDHEVKVKASNGRSLDTKVLQAPYEYITGLPSKRLREQAIDAMNVWFRVPAEKLDLIKSITTILHNASLMLDDVEDGSELRRGNPSTHTIFGLSQTINSANYQLVRALERVQKLEDSESLLVFTEELRNLYIGQSMDLYWTGNLICPTMNEYFHMVECKTGGLFRLFTRLMSLHSTSAVKVDPTTLSTRLGIYFQTRDDYKNLVSTEYTKQKGYCEDLEEGKFSLPLIHLIQAMPDNHVLRNILTQWRVTRKVTLAQKQVVLGLMEKSGSLKFTRETLASLYSGLEKSFTELEEKFGTENFQLKLILQFLRTE
What is the function of this protein?
Bifunctional terpene synthase that converts dimethylallyl diphosphate (DMAPP) and isopentenyl diphosphate (IPP) into astellifadiene (PubMed:27038368).  The C-terminal prenyltransferase (PT) domain of EvAS catalyzes formation of geranylfarnesyl pyrophosphate (GFPP), whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP to astellifadiene (PubMed:27038368).
What are the official names of this protein?
Astellifadiene synthase, SS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.
Protein: RS12_RHOBA
Sequence: MPTINQLVRKNRKQKKSQSKSPVLEKCPQKQGVCLQVRTMTPKKPNSALRKITRVRLSNGKEVTVYIPGEGHNLQEHSIVLVRGGRVRDLPGVRYQVVRGSRDALGVDGRKQSRSRYGAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GLUQ_KLEP7
Sequence: MTDSRYIGRFAPSPSGELHFGSLIAALGSYLQARANQGIWRVRIEDIDPPREVPGAADTILRQLDHYGLHWDGDVLWQSQRHEAYREALTWLGEQGLSYYCTCTRARIHAVGGIYDGHCRDLGLGAENAALRLRQTRPVLQFSDRLRGTLIANEPLAREDFIIHRRDGLFAYNLAVVVDDHFQGITEIVRGADLIEPTVRQISLYQHFGWQAPDYLHLPLALNGDGNKLSKQNHAPALPEGDPRPEIVRALRFLNQAIPEEWQALNIDDLLAQAVANWQPAKIEHSQMAPAEL
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: RNPH_MYXXD
Sequence: MRSFQRGALDLRPVVLTPGVSRYAEGSVQVEFGHTKVLVTCSTEERVPPHLMGKGSGWVTAEYGMLPRATHSRNQRESAKGKQTGRTMEIQRLIGRSLRAAVDLSTLGPRTLTLDCDVLQADGGTRTASITGAYVALVLALRSLQKAGTISKLPKLTPLAAVSVGIVKGEVRVDLDYDEDSTADVDLNLVATADGRMVELQGTAEHQLFDRKALDAMVDGGLAAIQKLTAAQAQVLG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: YJ27A_YEAST
Sequence: MTLMSGEGQGKSSSVKRVPTIAATLVFFFSNSFLPASR
What are the official names of this protein?
Putative uncharacterized protein YJL127W-A.
Protein: SPT6_CRYNB
Sequence: MSDRPGSASEGEGDEIRPYGEDRDSSEESEDDDPEEAKRIAEGFIVDEDEEDGEGEDDEEDEETRRRRRKEEKRRRKKERRMRREREEAELSEDELELIEENRGLREGRPLKRLRRRSGSEGSENDRAVPTLQDMFRDDEDRMEDDDDDLMDFIEEDEEDEANQGETEEQRRERKRAEKLKRREQARSRPELTGVDRSSWDEIFAVFGDGQDYDWALEGEDGMDLDEEEEAAKKDLRLEDVFDPAEIKARRLQDEDKAVANADRPERHQIVNSTLSDNPVFATDTLYPPPDFAAKWVAPKVSFRTQYLFYNQHPEGSYPIPTIDNPQPYPVYRRPDLEIEFEKAVSTALNMMFVQHLEVPYLWHYKRDVFSLLENQGQSSVLFLERDELWQVYVLGQRYRAIHERNEQTRQQWGKIKARKGDIEDEYFTKGLLGKACVASIEAAGEGDEWLAYHYASDIKAIKEEEAFDEVSKKLPERAEREDIRRGRIMKLVEAFGIDANKVASSFQDVHGQPAPVMNPDKMPLELADEFTGAAYSSPEQALSAASFVLVQELSKDPAIRQQARDFMDTCGLVTVNATDRGMSVIDQYHLYYNFKFLTNKPVPDFRDSPQFVHMLKAEEEGLINIAFDIREDMLASFTDALIRCCRSNDYGEIASAWNEVRMEVCNTLVKKHLMPMASKWIKEHLRTQAEEYIAERCREELELRVNVRPYASSGMEQGETPSVLAITNGKGDIRDAVMAVMLDDEGNVRTQTKFDNLRDEEDKTMFIELLEKRKPKVVVIGGFSAQTARLKDAALVAIRQHAIELLGQNPPVSDAYPDHEGFQYAMAEYDEKLKAHLIPLIFVNDATARLYMSSEEAEKEHPNLPLNGRYALGLARYAQNPLNAYCKLGKHIASVTFMEHHQKLIPQEKLLYHLERGLVNSVCFMGIEINSCVADPYQRAMLPYIAGLGPRKADAVIYGIQKHGALINRMAFTDLGLFGPTIFENTAGFLTIESDLKDMMLEAENPQEQPDPLDMTRIHPENYEFAQKMCQDALDLDVEDVADRHKSEVVQTLMLDDKRGKKLGELNLDDFAFNLQRQGEGNKRHTLGEIVSELIRYRSDRRPAFYVPTDWEIVTMVTGETERTVGRGLKVTATVRKAISARVFCQLESGLDAVLERDYVADEDQAPVTSCDEVFKPRQAIKGVVIMPEPARFQVRISTRPSDLRQGVDFVQPFKDEEYNSKDRRDAAEAATAAKKQRRAGKVQRIVNHPNWHVLNSGQAEQFLASQHRGDCVIRPSSKGPDRIAVTWKVDEDVYQHIDVQEIDKPNEYSLGRILMVSGQYRYSDLDDLIINHVKATARKFDEIQMHEKYKPEHELDAFLKNYVQAHPGRSIYGFSVDSDRPGYLKLCFLSKPTKDGGVIQTWPVRVLPGAYKLGNAIVPGVTELSNAFKMQYSEKLAEQGHQGKTPGIYLGKTPMHLGGRTPALGSRTPAMGSRTPALGSRTPALGSRTPALGSRTPAQGGPRY
What is the function of this protein?
Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters.  Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT6, Chromatin elongation factor SPT6.
What is the protein family that this protein belongs to?
Belongs to the SPT6 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCH1_ECOLC
Sequence: MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQILIALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DAPB_NATPD
Sequence: MNVVVVGATGRTGSEIVAEASERGHDVSGVARSQTSVGDVRVYPTEEFPELLDNADAVIDFTVPEATREHVQAAAAAGVPYVIGTTGFDDDGMAALRTASESTAVLKASNFARGVQALLRVVEAGVEALPEYDIELTETHHNGKRDAPSGTANTILDVVDETRDEALDRTHGREGEHRRGDDEVGVHVRRAGTVRGEHELLLAGNDEVLSLTHRAESRRVFAAGAVDAAEWLADRSAGWYDFEDTV
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FGF17_RAT
Sequence: MGAARLLPNLTLCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAERQKQFEFVGSAPTRRTKRTRRPQSQT
What is the function of this protein?
Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain.  Required for normal brain development.
What are the official names of this protein?
Fibroblast growth factor 17, FGF-17.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: VDAC3_BOVIN
Sequence: MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLRTKSCSGVEFSTSGHAYTDTGKASGNLETKYKICNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSLGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYKLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFNAGGHKVGLGFELEA
What is the function of this protein?
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity).  Involved in male fertility and sperm mitochondrial sheath formation (By similarity).
What are the official names of this protein?
Voltage-dependent anion-selective channel protein 3, VDAC-3, Outer mitochondrial membrane protein porin 3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Membrane. Note=May localize to non-mitochondrial membranes.
Protein: FTHS_SYNWW
Sequence: MKTDVEIAQSAKMQPITEIADRIGIEPNELELYGSYKAKISLDIMKRIEDKPQGKLVLVTAISPTPAGEGKTTTTIGLGQALNKIGKKAIVALREPSLGPVFGIKGGATGGGYAQVVPMEDINLHFTGDIHAVTTAHNLLAALMDNHLHQGNELDIDSRQIVWRRVMDLNERVLRNIVLGLGGRINGVPRESGFDISVASEVMAALCLATDLMDLKERFAKIVVAYSQQGQAITAGDLKAAGSMALLMKDAIKPNLVQTLENTPAFIHGGPFANIAHGANSIVATRLGVKLADYMVTEAGFGADLGAEKFFNIVCRYGKLVPDAVVLVASIRALKHHGGVKKDKLGEENLEALAQGMENLKKHLENIQKFGVPAVVALNEFPSDTSKEIDYVFSQCAAMQTAVSISRVWAQGGEGGIDLAEKLVLATEQGSQFKFLYELNQPLKNKIETICREIYGAGSVKYAAEAKRMLQKYEESGFGDLPVCIAKTQYSLSDNAQLLGRPTGFEVNIRQVKLSAGAGFVVALAGDIMTMPGLGKVPAAENIDIKPDGEIVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RM33_TETNG
Sequence: MFLTTANLAKAKSKTILVQMVSAAGTGYFFNTKRNRLRDKLVLRKHDPVVNKHVLFFEKKKIRSI
What are the official names of this protein?
39S ribosomal protein L33, mitochondrial, L33mt, MRP-L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LEU1_SEDSS
Sequence: MPRRIKIFDTTLRDGEQSPGASMSLEQKIKMASALERLGVDRIEAGFPVSSPVQFEAVQRVSATVKKAEVVGLARCVQRDIDAAYDALRDAAHPMLHIFIATSPLHREYKLKKSKEEILDTVRECLNYGGKGFSRMEFSPEDASRTEPDYLVEVVKTAIECGATSINIPDTVGYAVPKEFGQLISFLVEQVPQFSDGSVDLSVHCHNDLGLALANSLAAVRSGASQVEVTLNGIGERAGNCPMEELIMSLDVRKDMFDVETGIHTEYLYPTGKLLQSITGLLIPRNKPIFGDNVFVHESGIHQHGVLNKRETYEIMKPERIGRSSETIIMGRHSGKHALEDKLSQYNIKLTRQQFEDVFARFTAIADKKKEVYDEDLFSIVGTVLGGVVKGFSLLYFHTFTGNSLIPGATVKVRSEAGEKVASATGDGPVDAVFNAIDECVGINARLKEYIIHAIGSGKDAQGEVKLEVEIEGATYGGKASSTDIIEASAMAYLNAVNRFELRKR
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: MDFI_MOUSE
Sequence: MSQVSGQCPSRCDAPHGVPSAALDPAQTMSLLPGLEVARSTHPVEASSEEGFPEEAAPSMPHDSGLRAQQALNSIDLDVPTEAVTCQPQGNPQGCTPLLPNGSSHDHLSEPGSAGHAGNGALGGSKAHRKLQTHPSLGSQAGRKSRGSARSASQVPLQAQEGKAPAVRIHRQTASPTCCLRNAQLSGTALRSLRLESQGHRELNNKTLSQSNNKKPGVAAHAAIIPALTRPKQNCHDPSLLPGTHGVGKEF
What is the function of this protein?
Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis.  Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals.  Can also interfere with the DNA-binding activity of Myod family members.  Plays an important role in trophoblast and chondrogenic differentiation.  Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA.  Binds to the axin complex, resulting in an increase in the level of free beta-catenin.  Affects axin regulation of the WNT and JNK signaling pathways.
What are the official names of this protein?
MyoD family inhibitor, Myogenic repressor I-mf.
What is the protein family that this protein belongs to?
Belongs to the MDFI family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SYT_THIDA
Sequence: MVTVTLPDGSVRPFEGPVTVAEVASSIGAGLAKAALAGKVDGKLVDTSYVIDADAQLAIVTAKDAEALDLIRHDAAHVMAQAVQELYPGTQVTIGPAIEDGFYYDFAREQPFTPEDLEKIEKRMDEIVKRDLPIRREVWSRDEAMKVFGDLGETYKVQIIDEVIPKGEELSIYRQGEWFDVCRGPHLPSTGKLPRAFKLMKLAGAYWRGDSKNAMLQRIYGTAWAKKEDLEAYLHRLEEAEKRDHRRLAKQLDLLHMQDEAPGMVFWHPKGWIVWQQIEQYMREKFVEYGYQEVRTPAVMDRSMWEKSGHWENYRDNMFTTASENRDYAVKPMNCPGHVQIFNSGLHSYRDLPLRLAEFGSCHRNEPSGALHGIMRVRGFTQDDAHIFCMEEQVEQEVADFIVMLQKVYADFGFNDVLVKLSTRPDKRVGSDESWDKAESALAAALEKNGLSFDLQPGEGAFYGPKIEFTLKDTLGRLWQCGTIQLDFNLPVRLGAEFVAEDNTRKIPVMLHRAILGSMERFIGILIEHHAGNFPLWLAPVQVMVMNISERQAAYAEAVAEALRRAGIRAALDLSNNKINYKIREHSLQKLPYQLVVGDKEMEARVVAVRARGNQDMGQLGLDDLIARLRAEVLARQ
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP4_METBU
Sequence: MDRKIVIPGQLLSEKKEMAGPGTYVKNGNIYSLLYGIANFKGRVSVVPFSGKYIPSRKDFIIVNVIDVTPSNWIMETGSPYDGLLHVSEFPKRVDSSEMRKFMDVGDCVIVRVKDVSKAMKVELSMREQGSRALSKGRIIEVVPSKVPRVIGHGGSMVSILKKESNCDVFVGKNGRIWINGKDKDMDRLTTAIEMIESESHMSGLTDKVGMFLRGEPEGTEGSDEEQLVDEEVAGVSLEDDDVTEETSRKVDVLLDNDTDETN
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Increases the RNA binding and the efficiency of RNA degradation.  Confers strong poly(A) specificity to the exosome.
What are the official names of this protein?
Exosome complex component Rrp4.
What is the protein family that this protein belongs to?
Belongs to the RRP4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF335_IIV6
Sequence: MEFHCKELDFSLKKVESDEKVKRKPGRPRKHNVRPVVKDVPIGNDFDKATITTKTFTIKVENFDPDIDIWRNQISVSNVQHNDLECRCKDKIFPYTKPHKPGDIVEEYVFSKKNTKNIEKKENVFKNCFTVVILDQSLKPTTIKICKKGSFQLTGCLSMESGEFCVLSLITNLQKKNPQWIPSLIDMTIKPVMTNVKFTIGYKISIVKALNFFENRKDIHEFFSYKLRVNPAINIKELLTEKDLENVPVRIVTYVNVNNKIYNRTSQEITLLNHIQTLSLKEKQKHFKEKHTTLLLFRSGSVILSGIHENVMKKTFESFQKVTSDYKSYLT
What are the official names of this protein?
Uncharacterized protein 335L.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 335L family.