PharMolix/UniProtQA huggingface dataset:
Protein: IGF1_BOVIN
Sequence: MGKISSLPTQLFKCCFCDFLKQVKMPITSSSHLFYLALCLLAFTSSATAGPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARSVRAQRHTDMPKAQKEVHLKNTSRGSAGNKNYRM
What is the function of this protein?
The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity.  May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts.  Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake.  May play a role in synapse maturation.  Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb.  Acts as a ligand for IGF1R.  Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways.  Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4.  Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.  Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (By similarity).
What are the official names of this protein?
Insulin-like growth factor I, IGF-I, Somatomedin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VPS51_XENLA
Sequence: MATVEEEESAKKKKSHGILKLYYGMTEEGKAAERHLEPTDVDGVHFNPELYLTKLRKESSLSQLMDVEADMVRQIRSLDSEMQTLVYENYNKFISATDTIRKMKNDFKKMEDEMDGLASNMAVITEFSARISSTLQVSHQQITKLSGVHTLLRKLQFLFELPARLKKCIELGAYGQAVSYHSKARSVLHQYQHMPSFHGIQTDCQAIMAGLADTLRQRFRDPASSPQELSECVEMLLNLEEPAHLLCDEFLAHGRGRLASHLSDLQESGDILEFVDRGCGGFISDACLLAASYQSLFSKEPGNSAQMAEAKLTVFLEELSTGYFELVEKRLHQEKSLGDNSLLVRALDRFHRRLQAPSKLVPGCGFNRRGTEIVVRAAQERLAQYLQSLKEFFQGCLTDVRQALAAPRLPGKETSGLGDLLAGLSASVLNQIKTVLAAVHLFTAKDVAFSNKAYFKGEFCSQGVREGLIVAFITSVCQTARQFCEIPGEKGTSTPPSLLLLLSRLCLDYETSTISYILTLTDEQFLGQDRSPVTPVSSLCSLARSTAQTLLNQFVKYQGLVVSQMLRKSVETRDWVTTIEPRNVRAVMKRVVEDITGVDVQVGLLYEEGARKAHSSDSSKRTFSVYSSSRLQGRYAQSYTPSAPMDTNLLSNIQKLFSERIDIFSSVQFNKVSILTGIIKISLKTFLECVRLRTFGRYGLQQIQVDCHYLQLYLWRFVSDENLVHCLLDEVVGSAAHRCLDPAPMEQSVIEVICERG
What is the function of this protein?
Involved in retrograde transport from early and late endosomes to the late Golgi.  The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy.  Acts as component of the EARP complex that is involved in endocytic recycling.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 51 homolog, Protein fat-free homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS51 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.
Protein: PTF_TALMQ
Sequence: MDRNQWTLALMALMRFAHRAFINPVSPLPKFSRLAFTQGASRLYATLHVDAGLQDNVVDKAAKPYLSRRLKFNAEHFKQDVSELCTTLNADYNEGVMNAVLNTYKENFERGAVLWKATSKEDGVAFRFYERKKVDVVGPAINNSLISGNHGMIPLITSWANFKKNAIASCDFDPAKGLCKTWIWLGGRHPTRDLLVAPNVPGTIRSLERKLISAGLHTVRHAAVDWRSSTVNLYFWVPRPLTLPVVNTLITLPGTPPINEEKLTLMKPFFKPNGFTFATTIDTATGKFKRVSFYALRLDGNNLPIMGDQLATFFKDAPSNDKTEMNIVAWSFAGGSNGSSNYIKGERSYIGDLEQVLDAWGSPI
What is the function of this protein?
Prenyltransferase that attaches isoprenoid moieties to carbon atoms of aromatic substrates in an enzyme-catalyzed Friedel-Crafts reaction.
What are the official names of this protein?
Aromatic prenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the aromatic prenyltransferase family.
Protein: ISPE_PARL1
Sequence: MSGPVTEAARAKINLTLRVLGKRADGYHELQSLVVFAQSGDRLTAREADELRLDVAGRFAAALQGEPDNLVLRAARMLREETGIKSGAHLTLEKNLPVASGIGGGSADAAAALRALTALWGVAPGDEVLSRIAAALGADVLVCLHSRTAMMWGKGEKIMPLADLPRFWLVLANAGIALSTAAVFRELAAAPLAAAPSDPAPVPPGTLDDLAAWLAAEGNDLEPPALTLAPEIGETISALALTAGCLLARMSGSGATCFGLYAAEEEAREAALVLQAAHPGWWLEVSAAGG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PHF10_RAT
Sequence: MAAAGPGAALSPRRCDSDPASPGAQSPKDDNEDNSNDGGHPSKRRRMGSGDSSRSCETSSQDLSFSYYPAENLIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYLRELNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYSQMQQQSTQKVEASKVPEYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHVIQVPQGKYKVLPTDRTKVSSYPVALIPGQFQEYYKRYSPDELRYLPLNTALYEPPLDPELPALDSDGDSDDGEDGGGDEKRKNKGTSDSSSGNVSEGDSPPDSQEDTFQGRQKSKDKMATPRKDGSKRSVLSKSVPGYKPKVIPNALCGICLKGKESNKKGKAESLIHCSQCDNSGHPSCLDMTMELVSMIKTYPWQCMECKTCIICGQPHHEEEMMFCDVCDRGYHTFCVGLGAIPSGRWICDCCQRAPPTPRKVGRRGKNSKEG
What is the function of this protein?
Involved in transcription activity regulation by chromatin remodeling.  Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors.  During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state.  The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.  As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF).  The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.  The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
What are the official names of this protein?
PHD finger protein 10, BRG1-associated factor 45a, BAF45a.
What is the protein family that this protein belongs to?
Belongs to the SAYP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: A1OA1_LOXVA
Sequence: WIMGHMVNSLAQMDEFVGLGSNSIETDVSFDKQANPEYTYHGVPCDCGRSCGHSTKFNDFLKGLRKATTPGDSKYHEKLILVVFDLKTGSLYDNQAYDAGTKLAKNLLQHYWNNGNNGGRAYIILSIPKLNHYKLITGFKETLKNEGHEDLLEKVGHDFSGNDDISEVQKTYNKAGVTGHVWQSDGITNCLLRGLSRVKAAVANRDSGRGIINKVYYWTVDKRSTTRDSLDAKVDGIMTNYPDITVEILNEDAYKTKFRIATYEDNPWETFKE
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LvSicTox-alphaIC1ai, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_RICCK
Sequence: MSKIPSVNIKELLDAGVHFGHKTSRWNPKMGSYIYGERDDVHIIDLRQSAVLMSVALNAIYETVKKDGKILFVSTKIQASDIIAEYAEKCGQYYVNHRWLGGMLTNWKTIAGSIEKLNKLEKTLGNEEALMGYTKKEILDMSRKKDKLLLSLAGIRNLNSKPDLLVVIDTNKEHIAINEAVKLNVPIVAVVDTNSNPDNVDYPIPGNDDSIRSIRLYCSLFADAALQGLAESMKASGVDMGAIQEHTDKALTSKSVSKLKQTKKFSKMKNIDEETNTEFEQALNDADKNKNSENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RR9_THAPS
Sequence: MNTVFQKDKIGIGKRKRAVARVFLVPGTGTITINKVSGEKYLQYNTNYLNAIKAPLEKLNLTNQFDIVAIVRGGGLTGQTDSIKLGVARLLCKMEHENRLVLKPFGFLSRDARIKERKKYGLRKARKASQYSKR
What are the official names of this protein?
30S ribosomal protein S9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y152_UREPA
Sequence: MKLSRRLTNMTNWDKEHALSEELRQLKDEFEDLMDDLARINKDLDFNIWERKDLEYRKASYETDIESIRLRINQKQNEMMEIIKNDK
What are the official names of this protein?
Uncharacterized protein UU152.
Protein: CCME_ECOL5
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: SYR_PARL1
Sequence: MNIFRFFEGRVEAALRSLEEEGVLPSGLDLTRVAVEPPRDPSHGDLSTNAAMVLAKPAGMKPRELAEQLAVKLGGEEAVTEVDVAGPGFINLRLNPAFWQARIPEILRSGPAYGASDVGAGEAVNVEYVSANPTGPMHVGHVRGAVFGDALCNLLEKVGYRVCREYYINDAGGQIEVLARSAFLRYREALGEDIGQIPEGLYPGGYLKPVGQALVAAHGRSLLEKDEPEALSIVREAAVEAMMELIRGDLGVLGIVHETFFSELALHRSGFVEQTLKVLEDKGLIYIGELEPPKGEVPDDWEARPQTLFRSTEFGDDTDRALKKSDGSWTYFAPDIAYHLDKYNRGYRTLIDVWGADHSGYIKRMRAAIAGVTDGNAEFDVKICQLVRLFRNGEPVKMSKRSGDFVTLREVVDEVGKDVVRFMMLTRKNDAPLDFDFAKVMEQSRDNPVFYVQYANARIHSVLRNVAEEGTYDLSDGALANADFTLLTDEAEMALVRLMAGFPRLVEQAALAHEPHRIAFYLDDLAAAFHGLWNKGKDDHSLRFIRADHRDVTLARLALIRSAAYVIAAGLAILGVEPTEEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACBP_DICDI
Sequence: MTTFEEAAQKVKEFTKKPSNDELLSLYGLYKQGTDGDCNISEPWAVQVEAKAKYNAWNALKGTSKEDAKAKYVALYEQLATKYA
What is the function of this protein?
Binds to acyl-CoA.  Processed into the SDF-2 (spore differentiation factor 2) a peptide which triggers sporulation.  SDF-2 appears to stimulate prestalk cells to release additional SDF-2 by acting through a signal transduction pathway that also involves dhkA, regA and PKA.  Induces encapsulation of prespore cells in a dhkA-dependent manner.  GABA induces the release of acbA from prespore cells and induces the exposure of tagC on the surface of prestalk cells where it can convert acbA to SDF-2.  Glutamate acts as a competitive inhibitor and is also able to inhibit induction of sporulation by SDF-2.
What are the official names of this protein?
Acyl-CoA-binding protein, ACBP.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
Protein: SUFE_ECOSM
Sequence: MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSPQNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_EDWI9
Sequence: MTKKKAYKPGSATIAMNKRARHDYFIEEEFEAGLSLQGWEVKSLRAGKANISESYILLQNGEAFLFGATFTPLNVASSHVVCDPTRTRKLLLKERELASLFGSANRDGYTIVPLSLYWKNAWAKLKIGVAKGKKEHDKRDDIKTREWKQDKARIMKNANR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: XGPT_ECOUT
Sequence: MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFITIFAKPAGRPLVDDYVVDIPQNTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TIG_BRUSU
Sequence: MQVTETLNEGLKREIKVVVPAGDLEAKLAERLETARGRARINGFRPGKVPTAHLRKMYGKSFMAEIVNEILNDLSRSILAERNEKSATQPEVIMSEDEKEAEKVLDGKADFVFSLNYEVLPAIEVKDFSKIAVTREVVDISDEEVDEQVKRIASSTRTFETKKGKAENEDRVTIDYLGKLDGEPFEGGADNDAQLVLGSGQFIPGFEEQLIGLKAGDEKVITVTFPAEYGAAHLAGKEATFDIKVKEVAKPNELVLDDETAKKLGIESLERLRQVVREQIESQYGQVTRQKVKRQILDALDGDYQFETPQKLVDAEFNNIWQQINFDLQQAGRTFEDEETTEEAAREEYRKLAERRVRLGLVLSEIGEKAGVEVTEEELQRAVYDQVRRYPDQEKEIYDFLRRTPDAVANLRAPIFEEKVVDHLLANINVTDKKVSKEELTAEDEDAASEAKPAKKAAAKKKAAPKKKAEEGKSEEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: B2MG_MESAU
Sequence: MDKVELSDLSFNKDWSFYLLAHREFVPTATDKYACRVSHITLKEPKVVTWERDM
What is the function of this protein?
Component of the class I major histocompatibility complex (MHC).  Involved in the presentation of peptide antigens to the immune system (By similarity).
What are the official names of this protein?
Beta-2-microglobulin.
What is the protein family that this protein belongs to?
Belongs to the beta-2-microglobulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CD44_HORSE
Sequence: MDKFWWRAAWGLCLVPLSLAQIDLNITCRYAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMQKALNIGFETCRIGFIEGHVVIPPIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFEGPITITIVNRDGTRYTKKGEYRTNPEDINPSTPADDDVSSGSSSERSTSGGYSIFHTHLPTTRPTQDQSSPWVSDSPEKTPTTKDRASGGRAQTTHGSETSGHSTGSQEGGASTTSGPIRRPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINNGNGAVDDRKASGLNGEASRSQEMVHLVNKESSETQDQFMTADETRNLQNVDMKIGV
What is the function of this protein?
Cell-surface receptor that plays a role in cell-cell interactions, as well as cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment.  Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection.  Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases.  Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion.
What are the official names of this protein?
CD44 antigen, Extracellular matrix receptor III, ECMR-III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, Phagocytic glycoprotein I, PGP-I.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, microvillus. Note=Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli.
Protein: RPOB1_STIHE
Sequence: MAIEKYFIPDFVELQRRSFQRFLETGLIEELNKRNPITNSQKDLEILLYPEYYKLAPPRWNSLDAILLSKTYSCRLYVPAQLTNRKTKQIMFKWVQLGDIPLMSKRGHFVVNGAARVIINQIVRGPGLYFSEIQYNVDSSKKTLVRRYAAEFISMRGTWLRLSIDKEKMIWAELKKTPKIPLVWFLLGMGLTEKILFQSLTQPKRLLYNYLDYLKIDNLAIDVKSQNDAFAKRALLRELLLKSKLNSSNIKTLKNSKDFKPLLLVNDIYSEMHSYKEKENRRYPLNSQNGDLADEKEKIPYYANSSLKALELIYSKITNTKKITNLNKKFFAKQGQKWIFKKFMNPRTYDLGLHGRLSLNKKLSLSLPLSQRTLTMYDVLVATEHLLRVEQGLLGTDDIDNLKNRRVRTSSDLIQMQIGIGLLRLEKNIRSKFTTIKGVPKINYFFSTKPLNGALKEFFGTNPLSQFMDMINPLAEMTHKRRLTTLGPGGVSRDTATMDIRGIHPTHYGRICPVETPEGKNAGLVNALTTFARVNPEGLIETPFYKVYKGQVQKKAGFFYLSAEKEEKAIIAAGDLNLSKTGFLPKGLIPVRKFDEFTKVLRNYVDFMSVSPLQMISVATSLVPFLEHDDANRALMGANMQRQAVPLVRSEQAIVGTGIETRIASDSGHVIRAKAGGLVGYVSGQKIRIYTFVSNF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta N-terminal section, PEP, Plastid-encoded RNA polymerase subunit beta N-terminal section, RNA polymerase subunit beta N-terminal section.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DOF37_ARATH
Sequence: MDATKWTQGFQEMINVKPMEQMISSTNNNTPQQQPTFIATNTRPNATASNGGSGGNTNNTATMETRKARPQEKVNCPRCNSTNTKFCYYNNYSLTQPRYFCKGCRRYWTEGGSLRNVPVGGSSRKNKRSSTPLASPSNPKLPDLNPPILFSSQIPNKSNKDLNLLSFPVMQDHHHHALELLRSNGVSSRGMNTFLPGQMMDSNSVLYSSLGFPTMPDYKQSNNNLSFSIDHHQGIGHNTINSNQRAQDNNDDMNGASRVLFPFSDMKELSSTTQEKSHGNNTYWNGMFSNTGGSSW
What is the function of this protein?
Transcription factor specifically involved in the maternal control of seed germination.  Regulates transcription by binding to a 5'-AA[AG]G-3' consensus core sequence.  May ensure the inactivity of a component that would be activated to trigger germination as a consequence of red light perception.
What are the official names of this protein?
Dof zinc finger protein DOF3.7, AtDOF3.7, Dof affecting germination 1, RolB domain B factor a, Transcription factor BBFa, AtBBFa.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMG_ROSDO
Sequence: MFHVKHFDVLVIGGGHAGTEAAHAAARMGSQTGLITMSRSGIGVMSCNPAIGGLGKGHLVREIDALDGVMGRVADQAGIQFRLLNRRKGPAVQGPRAQSDRAIYHNRMLEATDQQQNLDIIVGEAVDFVMDGERVIGVVLQDDAEILAKTVILTTGTFLRGVIHIGDVSRSGGRMGDKASVRLADRIDSFGLPMGRLKTGTPPRLSSKSINWDVLEEQPGDDEPTLFSFLSKGVSARQVSCGITHTNVRTHDIIRDNITRSAMYGGHIDGVGPRYCPSIEDKIIRFADKESHQIFLEPEGLNTDAVYPNGISTSLPQDVQSEYVHSIVGLEKAIILQPGYAIEYDYVDPRALDSSLSVLSVPGLYLAGQINGTTGYEEAAAQGLVAGLNASLEARGSDPITFSRSDSYIGVMIDDLTTRGVMEPYRMFTSRAEFRLSLRADNADQRLTPIGLALGCVSDERKQAFEVKIEALDRARRLLTESSYTPKQAGEAGISVSHDGSRRTAMQLLAFPNTSFKDLSLLDPVFDGIDVETQQQMEREALYATYIERQQKDVDLLKKDEGHKIPADFDYDQLSGLSNELKSKLNSTRPTSLAQVGRIDGMTPAALTLILAKLRQSSKKRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_LEGPL
Sequence: MPELPEVETTKQGIKPHLEGCMITSVQVRNQKLRLPVPLNLNELCEGKHITAITRRGKYILLHMDKGYLLIHLGMSGHLRIVSQTANPQKHDHVDLHINNGLALRFRDPRRFGLFIYIDENPYQHPLLAHLGPEPLSDDFNSEYLLRKAANKSQSIKSFIMDSQIVVGIGNIYAAESLFLAKIHPNTSAKKITTEEFNSLTGHIKKILESAIEAGGTTLRDFYSSDGKPGYFRFALKVYGRKNLPCLVCENKIETVVIAGRHSAFCPHCQPIIT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: VAPB1_HAEI6
Sequence: MLTKVFQSGNSQAVRIPMDFRFDVDTVEIFRKENGDVVLRPVSKKTDDFLALFEGFDETFIQALEARDDLPPQERENL
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Upon expression in E. coli neutralizes the effect of toxin VapC1.  In vitro inhibits the RNase activity of VapC1.
What are the official names of this protein?
Antitoxin VapB1.
What is the protein family that this protein belongs to?
Belongs to the VapB family.