PharMolix/UniProtQA huggingface dataset:
Protein: COX11_DICDI
Sequence: MSRLFNNFLLKTNKNQFIQSFSTKSQINNNIFNNLIKNEKISLPPPPFLSSSSPLSMNNIFNRNNKNLYTTNNFNYNKLQFTTQSPNPTPTPTPTPTPTPTPNNNENNNNKNNNNNNFKEEQKKILQEKNKAIGLYVLIAIIGILGLSYAAVPLYRIFCRATGYGGTTRDADDFDVIRKRNLDRTVYPIKVTFSASTANKIPWTFKPTQSTIECLPGEPVLCFYRATNNTDTPIIGVATYNITPMKAGTYFTKIQCFCFDEQRINAHETIDMPVLFVIEPELLDDKNMKGVSDITLSYTFFKSNDQGEYEEI
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Protein: LOLA_SHIB3
Sequence: MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RS8_LYSSC
Sequence: MTMTDPIADMLTRIRNANMVRHEKLEVPASNVKKEIAEILKREGFVRDVEYVEDNKQGIIRIFLKYGKDNERVITGLKRISKPGLRVYAKTNEVPKVLNGLGIALVSTSQGLLTDKEARAKQVGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RS21_BORPD
Sequence: MPIVRLKENEPFEAALRRFKRTIEKTGLLTELRSREFYEKPTAERKRKHAAAVKRHYKRIRSQQLPPRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: KAD_SALTO
Sequence: MRLVLVGPPGAGKGTQAEFVAAHLAVPKISTGDIFRSNVSQGTPLGVQAKRYMDAGELVPDEVTINMVRDRLAEPDAGEGFLLDGFPRTTPQAAALDKLLVDLGTALDLVLELVVDDDEVIRRLSGRRTCRGCGKVWHVEFDAPSQEGRCDRCGAELFQRDDDKPETIATRLREYADKTAPLVDYYGAQSKLVGIDATGPVEDVTVRAIDALRSYSG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB2_CERSK
Sequence: MSWTIGRPDAEAPEDRMAASHLFTRLDDLVAWSRKHSLWPFNFGLSCCYVEMATALTPVYDQARFGAEVIRSTPRQADLLIVSGTVFRKMAVPLYRLYSQMREPRWVISMGACANSGGMYDIYSVVQGVDSFLPVDVYVPGCPPRPEALMEALVLLQSKIATEARPLQIRMGETGPARPFDPVPRRDALREARMAVTRLADPEAT
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KDSB_CYTH3
Sequence: MSSNISIVAIIPARYASTRFPGKPLIQINGKTMIQCVYDQVRSTPEITEVLVATDDDRIEAEVLRFGGKVVRTLPEHPSGTDRCFEAYQKLNKPFDFIINVQGDEPFIQPEQIRTLAGILTPDVELATLIKKIEDEETLFNPNTPKVLVNANGEAIYFSRQTIPYLRQHADKKDWLANHTFFKHIGMYAYRPDILAQITQLKPSALELAESLEQLRWLESGYSIHTAVTTIETVGIDTPEDLLRVTHTSS
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIS1_ORYSJ
Sequence: MASVTYIDDSGSEVIDPPKTEVLDVTELAGDPVPHSPKPNVVVSSSVRELLECPVCLSAMYPPIHQCSNGHTLCSGCKPRVHNRCPTCRHELGNIRCLALEKVAASLELPCKYQNFGCVGIYPYYCKLKHESQCQYRPYSCPYAGSECTVAGDIPYLVNHLKDDHKVDMHNGCTFNHRYVKSNPHEVENATWMLTVFSCFGQYFCLHFEAFQLGMAPVYIAFLRFMGDDLEAKNYSYSLEVGGTGRKMIWQGVPRSIRDSHRKVRDSYDGLIIQRNMALFFSGGERKELKLRVTGRIWKEQ
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (Probable).  Plays a negative role in drought stress tolerance through transcriptional and post-translational regulation of diverse stress-related genes.  Interacts with the serine/threonine-protein kinase NEK6 and promotes its degradation via the 26S proteasome-dependent pathway (PubMed:21719639).
What are the official names of this protein?
E3 ubiquitin-protein ligase DIS1, Drought-induced SINA protein 1, OsDIS1, RING-type E3 ubiquitin transferase DIS1.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear. Partially cytoplasmic.
Protein: LYSK_SULIL
Sequence: MQQEKELVKQKAKELLLDLLSIYTPSKNETNATKFFEKISNEFNLKLEILPDSNSFILGEGEILLASHVDTVPGYIEPKIENEVIYGRGAVDAKGPLISMIIAAWLLNEKGIKVMVSGLADEESTSIGAKELTLKNFNFKHIIVGEPSNGTDIVVEYRGSIQLDIMCESTPEHSSSAKSNLIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHFDVRYAINNKRDDLINEIKDKFQECGLKIVDETPPVKVSINNPVVKSLTRALLKQNIKPRLVRKAGTSDMNILQKITTSIATYGPGNSMLEHTNQEKITLDEIYIGVKTYMLAIEELWQKS
What is the function of this protein?
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
What are the official names of this protein?
[LysW]-lysine/[LysW]-ornithine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. LysK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_AROAE
Sequence: MSFMREFKEFAMRGNVIDLAVGVIIGAAFGKIVDSLVKDIVMPVIGRLLGGVDFRHLYINLGDQTYETMEAAEKAGAPLVKYGQFINTTIDFLIIAFAIFVAVKAINRLKRSEPPPPPAPVEAEEVKLLREIRDTLKRG
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LIDS_GAEGR
Sequence: MTVSTHHDDSPGLSGRLRDLLHHVFGNQKSPTVYPNAPGNSAKPVPTGLADDIDKLGFKDIDTLLIFLNSAVKGVNDDQQFLLEKMIQLLAKLPPASREGKKLTDGLINDLWDSLDHPPVASLGKGFSFREPDGSNNNIHLPSLGAANTPYARSTKPLVFQNPNPPDPATIFDTLMVRDPAKFRPHPNKISSMLFYLATIITHDIFQTSPRDFNINLTSSYLDLSPLYGRNHDEQMAVRTGKDGLLKPDTFSSKRVIGFPPGVGAFLIMFNRFHNYVVTQLAKINEGGRFKRPTTPDDTAGWETYDNSLFQTGRLITCGLYINIVLGDYVRTILNLNRANTTWNLDPRTKEGKSLLSKPTPEAVGNQVSVEFNLIYRWHCTISERDDKWTTNAMREALGGQDPATAKMEDVMRALGMFEKNIPDEPEKRTLAGLTRQSDGAFDDTELVKILQESIEDVAGAFGPNHVPACMRAIEILGIKQSRTWNVATLNEFRQFIGLTPHDSFYHMNPDPKICKILAQMYDSPDAVELYPGIMAEAAKPPFSPGSGLCPPYTTSRAILSDAVSLVRGDRFYTVDYTPRNITNWGFNEASTDKAVDWGHVIYKLFFRAFPNHFLPNSVYAHFPFVVPSENKLIFEGLGAANKYSWDPPKARAPIQFIRSHKAVLEVLSNQKDYKVTWGPAIKMLSGDPATSFALAGDEPANAASRHHVIAALTAPKQWRDEVRRFYEVTTRDLLRRHGAPVHGVGAGPRTHEVDVIRDVIGLAHARFMASLFSLPLKEEGKEEGAYGEHELYRSLVTIFAAIFWDSDVCNSLKLHQASKAAADKMSALIAEHVREMEAGTGFLGALGKLKDLITGNDVHANGNGVYTNGNGVYTNGNGVHTNGNGVHTNGNGVPHAAPSLRSFGDQLLQRMLSQDGRSIEETVSGTILPVVMAGTANQTQLLAQCLDYYLGVGEKHLPEMKRLAMLNTSEADEKLLKYTMEGCRIRGCVALYRAVVTDQAVDDTIPCIPNKDDPTFARPLSNPQVAESARTLKLSTGTRMLVDLTTASHDPAAFPDPDEVRLDRPLESYVHFGLGPHRCAGEPISQIALSSVMKVLLQLDGLRRAAGPRGEIRSYPASQWPGQAGRPPRDPAWSGLRTFTSADQSAFSPLATTMKINWEGRGDL
What is the function of this protein?
Catalyzes the dioxygenation of linoleic acid to (8R)-hydroperoxylinoleate and isomerization of the resulting hydroperoxide to (7S,8S)-dihydroxylinoleate.
What are the official names of this protein?
Linoleate diol synthase, Linoleate (8R)-dioxygenase, Linoleate 8-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family.
Protein: COAE_LEPIN
Sequence: MQNSDSGKKTFLIGITGMIGGGKSTATKILEEMGCFGINADRLAKRYTEPDSPILIELVELLGSEILDEQGKPDRKKISEIVFNNPEKLSRLNQLIHPLVRKDFQKILETTAKGKMVIWEVPLLFETDAYTLCDATVTVDSDPEESILRTISRDKVKKEDVLARIKNQLPLTEKLKRADYILRNRGNIDSLREECKSLYSTLLGKML
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU80_ASPFU
Sequence: MAEKEATVYIVDVGKSMGEKRNGRSMTDLEWAMQYVWDCITATVATGRKTATIGVIGLKTDETSNELDDDPHFKHISVFTEIQQFLMPDIRRLGALVKPSETDKGDAISAIILAIQMIVTYCKKLKYKRKIVLVTNGQGWMSNEDLDQITKKIKEDNIDLVVLGTDFDDPEYGFKEEGKDPRKAENEALLRGLVEDCNGAFGTLEQAVSEMDIPRAKRVRTVATFKGFLQLGNPEEYDTALRIPVERYYRTYVAKPPSASSFVLRSDVGAEGEQGESSQLPKSPPEGGALTSVRNLRTYEVPDENAPGGKFDVEREELAKGYEYGRTAVHISETDENITTLETYAALELVGFIQTDKYDRYMHMSTTNIIIGQRGNDKASLALSSFIHALFELECYAVARLVVKENKPPVMVLLAPSIEPDYECLLEVQLPFAEDVRTYRFPPLDKVITVSGKVVTEHRNLPNKDLLDAMSEYVDSMELVDTDETGNPVEGLPIDDSFSPVLHRIDSAIRYRAIHPDDPVLPPSKNLTKLSQPPQDLVEKSKAYLQKLMEAADVKKVPPKVKGRKRIRESEKPLSGLDVDALLHQEKRARISPTNAIPEFKQTLTQAETIETIKDAVKQMTSIIEDQIKNSLGDANYDRVIEEMGVMREELISFEEPALYNDFLRQLKDKLLKEELGGDRRELWWLLRRSQLGLINQRESDQSDVTEEQAKEVSLRCHLSSRGIY
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 2, ATP-dependent DNA helicase II subunit Ku80.
What is the protein family that this protein belongs to?
Belongs to the ku80 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RL11_CAMFF
Sequence: MAKKVVGEIKLQIAATKANPSPPVGPALGQQGVNIMEFCKAFNERTKDMAGYNIPVVITVYADKSFTFITKQPPATDLIKKAAGITKGADNPLKNKVGQLTKAQILEIVDKKIVDMNTKDKEQAAKIISGSARSMGITVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RPN10_YEAST
Sequence: MVLEATVLVIDNSEYSRNGDFPRTRFEAQIDSVEFIFQAKRNSNPENTVGLISGAGANPRVLSTFTAEFGKILAGLHDTQIEGKLHMATALQIAQLTLKHRQNKVQHQRIVAFVCSPISDSRDELIRLAKTLKKNNVAVDIINFGEIEQNTELLDEFIAAVNNPQEETSHLLTVTPGPRLLYENIASSPIILEEGSSGMGAFGGSGGDSDANGTFMDFGVDPSMDPELAMALRLSMEEEQQRQERLRQQQQQQDQPEQSEQPEQHQDK
What is the function of this protein?
Multiubiquitin binding protein.
What are the official names of this protein?
26S proteasome regulatory subunit RPN10.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5A family.
Protein: RDRP_CMVAS
Sequence: MAFPAPAFSLANLLNGSYGVDTPEEVERVRSEQRDEAAAACRNYRPLPAVDVSESVPEDAHSLRTPDGAPSEEVSVEFVTYGAEDYLEKSDDELLVAFETMVKPMRIGQLWCPAFNKCSFISSIAMARALLLAPRTSHRTMKCFEDLVAAIYTKSDFYYDDECEADDVQIDISSRDVPGYSFEPWSRTSGFEPPPICEACDMIMYQCPCFDFNALKKSCAERTFADDYVIEGLDGVVNNATLSSNLGPFLVPVKCPYEKCPTPVGEIPPDLNRATDRVDINLVQSICDSTLPTHSNYDDSFHQVFVESADYSIDLDHVRLRQSDLIAKIPDSGHMIPVLNTGSGHKRVGTTKEVLTAIKKRNADVPELGDSVNLSRLSKAVAERFFISYINGNSLASSNFVNVVSNFHDYMEKWKSSGLSYDDLPDLHAENLQFYDHMIKSDVKPVVSDTLNIDRPVPATITYHKKGITSQFSPLFTALFERFQRCLRERIILPVGKISSLEMAGFDVKNKHCFEIDLSKFDKSQGEFPFKIQEHILNGLGCPAPITKWWCDFHRFSYIRDRRAGVGMPISFQRRTGDAFTYFGNTIVTMAEFAWCYDTDQFEKLLFSGDDSLGFSVLPPVGDPSKFTTLFNMEAKVMEPAVPYICSKFLLSDEFGNTFSVPDPLREVQRLGTKKIPCSDNDEFLFAHFMSFVDRLKFLDRMTQSCIDQLSLFFELKYRKSGEEAALMLGAFKKYTANFQSYKELYYSDRRQCELINSFSCVELRIERSSSTKQREKKDGIERRRNDKRRTPTGSYGGGEEAETKVSQAESTGTRSQKSQREGAFKSQAVPLPTILSSRWFGTDRDVPPCEHGGIVRV
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 3 RNA segments, RNA1, RNA2 and RNA3.
What are the official names of this protein?
RNA-directed RNA polymerase 2a, protein 2a.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: Y1427_LEPBJ
Sequence: MSRFKKIKGDEGESIASDFLISIGHEILKRNYRFLYCEIDIISIKEEVLYFSEVKFWKEFESFDPRFTFNFAKQTRMRKAASGFLSENLSLQNHFVSFCLVSINEKKGCEYYPDLF
What are the official names of this protein?
UPF0102 protein LBJ_1427.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: PCKG_BORA1
Sequence: MTQAAEATLPPLNVPSYVKHARLIDWVQGVVALTKPARVVWCDGSQEEADRLCEQMVQAGTMRRLNPAKRPNSYLAWSDPSDVARVEDRTFICSQREEDAGPTNNWAAPAEMRNTLQGLFDGAMRGRTLYVVPFSMGPLGSPIAHIGVELSDSPYVAVNMRIMTRMGRAVWDVLGADGEFVPCVHSVGMPLAEGQADVAWPCNPVKYIVHYPETREIWSFGSGYGGNALLGKKCFALRIASTMGRDEGWLAEHMLILGVTTPKGRKFHVAAAFPSACGKTNFAMLIPPSGMDGWKVSTIGDDIAWIKPGQDGRLRAINPEAGYFGVAPGTSEKTNPNAMATLKANVIFTNVALTDDGDVWWEGMTDTPPAHLIDWQGKDWTPEIARETGRKAAHPNARFTAPASQCPSIDPEWENPQGVAIDAFIFGGRRSTTIPLVTEARDWVQGVYMAATMGSETTAAAVGQQGVVRRDPFAMLPFCGYNMADYFNHWLAVGQRLADAGATLPRIYCVNWFRKGPNGKFVWPGFGENMRVLKWMLGRLSGEAGGQEQVFGISPSYGDVDWTGLEFTPDQFQQVISVEAPAWREELALHGELFEQLAQGLPPALSRAKADIEHRLAAVQA
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA_I56A1
Sequence: MEDFVRQCFNPMIIELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARVKTRLFTIRQEMASRGLWDSFRQSERGEETIEERFEIRGTMRRLADQSLPPNFSSLENFRAYVDGFEPNGCIEGKLSQMSKEVNARIEPFLKTTPRPLRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMKTFFGWKEPNIVKPHEKGINPNYLLAWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFEDCKDVSDLKQYDSDEPEPRSLASWIQSEFNKACELTDSSWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIVKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRTAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSEKWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALK
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: COAE_STRCO
Sequence: MLRVGLTGGIGAGKSEVSRLLVEHGAVLIDADRIAREVVAPGTPGLAAVVAAFGEDVLAEDGSLDRPKLGSIVFADPEKLAVLNGIVHPLVRERSTALEEAAAEDAVVVHDVPLLTENGLAPLYDLVVVVDAAPATQLDRLMRLRGMTEQDARARMAAQATREQRREIADVVVDNDVPLEELRRRVEEVWDELVRGAHTE
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FXL21_BOVIN
Sequence: MKRNRLSFMNKVLQSSPAVKQPKLGCHSSLSQTHMRAALLDWGNLPHHVVLRIFQYLPLIDRARASSVCRRWNEVFHIPDLWRKFEFELNQSAASYFNSTHPDLIQQIIKKHAAHLQYVSFKVDSSTESAEAACGILSQLVNCSIQTLGLISTAKPSFLNMSKSHFVSALTVLFVNSISLSSIKIEDTPVDDPSLSILVANNSGTLRRLKMSSCPHVSSNGILCVADHCQGLRELALNYYMLSDKLLLALSNETHVNLEHLRIDVMSENAGQIEFHSIKRQSWDALIKHSPGVNVVMYFFLYEEEMETFFKEETPVTHLYFGRSVSKEILGRLGLNCPRLTELVVCANGIQVIDTELICIAEHCKNLTALGLSECEVSCSAFIEFVRLCGRKLTHLSIMEEVLIPDDVYSLGEIHTEVSKYLGRIWFPDVMPLW
What is the function of this protein?
Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function.  Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation.  The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization.  The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation.  Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 21, F-box and leucine-rich repeat protein 21.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=Mainly localizes in the cytosol. Present at low level in the nucleus (By similarity).
Protein: Y4303_CHRVO
Sequence: MMTALSCHGGCMDTHQLDAAEVRVLGALLEKQALTPDAYPLTLNALVGACNQLTSREPVMQLSESDASAALDALIAKKLVAERLPAGSRVAKYEHRLNYEWNIDGARLAALCLLTLRGPQTSAEIRARAGRIYSFSGVDEVETALNALADKYPPLAAKLERQPGEREARWCHLLSGEPQILPAQACEVIDVGLTGRVAALEAEVSALKAMVLALEQRLNG
What are the official names of this protein?
UPF0502 protein CV_4303.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: Y2212_MYCTO
Sequence: MYDSLDFDALEAAGIANPRERAGLLTYLDELGFTVEEMVQAERRGRLFGLAGDVLLWSGPPIYTLATAADELGLSADDVARAWSLLGLTVAGPDVPTLSQADVDALATWVALKALVGEDGAFGLLRVLGTAMARLAEAESTMIRAGSPNIQMTHTHDELATARAYRAAAEFVPRIGALIDTVHRHHLASARTYFEGVIGDTSASVTCGIGFADLSSFTALTQALTPAQLQDLLTEFDAAVTDVVHADGGRLVKFIGDAVMWVSSSPERLVRAAVDLVDHPGARAAELQVRAGLAYGTVLALNGDYFGNPVNLAARLVAAAAPGQILAAAQLRDMLPDWPALAHGPLTLKGFDAPVMAFELHDNPRARDADTPSPAASD
What are the official names of this protein?
Uncharacterized protein MT2268.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein: BCAT_CAEEL
Sequence: MPAILSRVAPRTFNLVGSRLMASAARLETVPREEIHKEYDRKKTFYHRDLEIQLAGPTQLKTKPLDPTKLKFGHTYADYMMTCDWDAERGWHHPKIEPIGELKIHPGAKVLHYASELFEGMKAYRGIDNKIRMFRPEMNMARMKRTALRAALPDFDSEEMINVLTELLRLDQEWVPNSDVCSLYLRPTLIGTDPTLGVGCATEAKMFVITGPVGAYYSTGFQPVSLLADSRFIRAFPGGVGAYKMGCNYAPTIWVGKEAASKNCQQVLWLYGENEDLTEVGTMNIFLFWKNEEGDMELITPPLHRGLILPGVTRDSLLELGREWGEYKVTERTLNMEEVKKALSEKRLYEMFGSGTACVVSPVGKILYHNKVTDEYEELHIPTMSSKFGVMQKFYNTINDIQYGRIIKDGWMRDI
What is the function of this protein?
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase, cytosolic, BCAT, ECA39 protein.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL41A_YEAST
Sequence: MRAKWRKKRTRRLKRKRRKVRARSK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L41-A, L47, Large ribosomal subunit protein eL41-A, YL41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL41 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_SULNB
Sequence: MAQHQVNYASAAGLPIALTSVDKLVNWGRSNSLWPLTYGLACCAIEMMASGASRYDFDRMGTIFRASPRQADVMILAGTLSKKHSEFARRLYDQMTEPKWVISMGSCANTGGMFNTYATVQGVDRIIPVDIYLPGCAPRPETLQYALMMLQKKIRRESANMNNNTKQNLRLV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TATA_XYLFA
Sequence: MGSFSLLHWLVVLVIVLLVFGTKRLANGAKDIGSAIKEFKKSLREDDKPTDQLGSTSQSTASGPQQDHGKH
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.