PharMolix/UniProtQA huggingface dataset:
Protein: RBL_DROPA
Sequence: GVGFKAGVKDYKLTYYTPDYETLDTDILAAFRVTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEDNQYIVYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTTKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAXTGEIKGHYLNATAGTCEEMIKRAAFASELGVPIVMHDYLTGGFTANTSLSHYCRNHGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRLSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDYIEKDRSRGIYFTQFWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGQDLAREGNEIIRKASKWSPELAAACEVWKEIKFVFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFTU2_YERPA
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSARAFDQIDNAPEEKARGITINTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPVIRGSALKALEGDAEWEAKIIELAEALDSYIPQPERAIDRPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIIDTIKTTCTGVEMFRKLLDEGRAGENVGVLLRGTKRDDVQRGQVLAKPGSIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNVNMVVNLIAPIAMDDGLRFAIREGGRTVGAGVVAKVIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 2, EF-Tu 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAR1_CANAL
Sequence: MSDTTPEKGSVDSVSPSASNGSNTNNPLNNSSPQPLKSNESDKKPKVTRRSVACKSCHSLKVKCTPSDPNNPSAPCVRCINANRICEIDLNQTRKRRKKSEILEAKRQAGQSLPEHKKEKNTPTQSGYNSSENYSSSINNANDSSLTSRYQSPMTFDPTSPMVFRPQASSAVPPISSNLNPQSAAPTPIPTSGIPPQLPSPHESAILRGNTTSPTSKDDEINQLKQRVRFLETELANKRLLANKKGFSNDSPTDLQSPPFVSKFDLESEISILAESSARLTDLTNQLNEAASRRIQLVSAKKPVDLISKGVITVAEAEERLKLYREQIYGRHPLIAIPDNMHAIEFSQSQPFLFNSIMSACNLITKNADKDVVLAIDNEAMTSVAVEVMVVGTKSVELVKAFSVLCLYYNSPELFKQRRYHMLNTICVSLLHDVGIFARPTYSYNQADGTLKQDASSKDKGNDEYRELVLITYFVTVSTCLVLRRSIYARWTPYVEECCSLLENSSQEKHRRLALFARMNNKLDKIHHIVHAPEMPGQKSGVSQYVIQELQRLLSDLKLKIKDNQYSLLSYYYSIEAYLHEPILTKVFKSDTELDGKAMKSIRYCTSSCLNALDEYSKLTPDQIALLPFPFGSRIMYTAGMLLRLRYLILSLPSHIDKELVPKRAVTSIQCVSKLVEQANILNPHNHYLTKMRLVLQLFIQTYATQVLELLSKNGNTPQNFKPDESETQQLRALAREYNDIRKVSKVSLVSDTRSAEPLDVLSYAATFRRENNDKPSAVAGSLRKSFSENDQAIKTPSQCGQFVSANNTPVPQVINSPPISQTNVPVLHQSQSIINGNNRNSAPLAFNNTTTPSLHQFGDVLPPSSMPQPDYRQFRLPSISNTVHYSSNPRLNANLANPDQLENSYQVLNDEFWSNLLSTDSTDRINFTSNNFNGNTSNDEVFFMNN
What is the function of this protein?
Transcription factor required for yeast cell adherence to silicone substrate.  Plays a role in resistance to weak organic acids such as acetate and sorbate.  Binds in vitro to a nitric oxide-responsive element (NORE) but seems not to be involved in response to nitrosative stress.
What are the official names of this protein?
Transcriptional regulator WAR1, Weak acid resistance protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAMP3_RAT
Sequence: MATPAQRLHLLPLLLLLCGECAQVCGCNETGMLERLPRCGKAFAEMMQKVDVWKWCNLSEFIVYYESFTNCTEMETNIVGCYWPNPLAQSFITGIHRQFFSNCTVDRTHWEDPPDEVLIPLIAVPVLLTVAMAGLVVWRSKRTDRLL
What is the function of this protein?
Plays a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a GPER1-dependent manner.  Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) and GPER1 to the plasma membrane.  Acts as a receptor for adrenomedullin (AM) together with CALCRL.
What are the official names of this protein?
Receptor activity-modifying protein 3.
What is the protein family that this protein belongs to?
Belongs to the RAMP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane; Single-pass type I membrane protein. Note=Moves from intracellular puncta to the plasma membrane in a RAMP3-dependent manner.
Protein: CH10_SALTI
Sequence: MSIRPLHDRVIVKRKEVESKSAGGIVLTGSAAGKSTRGEIIAVGKGRILDNGTVQPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_VIBCH
Sequence: MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLNVDVMQLRSKLGEMLDRLPKVSGIGGDVQLSSALGSLFNLCDKVAQKRQDAYISSEIYLLAAIEDKGPLGHLLKEFGLTEKKVSEAIEKIRGGQKVNDPNAEELRQALEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIINNEVPEGLRGRRVLSLDMGALVAGAKYRGEFEERLKSVLNELAKEEGNIILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDPALERRFQKVLVDEPTVEDTIAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASSIRMQIDSKPEALDKLERKIIQLKIEQQALSNEHDEASEKRLAILNEELQEKERDYAELEEVWKAEKAALSGTQHIKAALEQARMDLEVARRAGDLNRMSELQYGRIPELEKQLDLAAQAEMQEMTLLRNKVTDAEIAEVLSKQTGIPVSKMLEAEKEKLLRMEDVLHKRVIGQKEAVEVVANAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLANFLFDSEDAMVRVDMSEFMEKHSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSSRIQENFARLDYQGIKEQVMDVVSKHFRPEFLNRVDESVVFHPLGQEHIKSIASIQLARLRQRLAERDYQLEVDDEALDLIAHVGFDPVYGARPLKRAIQQNVENPLAKSILAGKFLPGSPILLSVKDGNIFASQ
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_LISMC
Sequence: MYYYLITLAVIALDQLTKWIVVQNMEIGQKIEVIPGFLYWTSYRNDGAAWSILEGHMWFFYLITVVVIGIIIYIMQKYAKGKRLFSISLAFILGGAIGNFIDRVLHQEVVDFVQTVWGNYYFPIFNVADAALSVGVVLMLVYVFVDDRKTKGIK
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LYSC_NASLA
Sequence: MKALIILGLVLLSVTVQGKIFERCELARTLKKLGLDGYKGVSLANWVCLAKWESGYNTEATNYNPGDESTDYGIFQINSRYWCNNGKTPGAVDACHISCSALLQNNIADAVACAKRVVSDPQGIRAWVAWRNHCQNRDVSQYVKGCGV
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: YTFE_SALPA
Sequence: MAYRDQPLGELALSIPRASALFRQYDMDYCCGGKQTLARAAARHDVDIDIIEAQLAQLAEQPIEKDWRAVPLADIIDHIVVRYHDRHREQLPELILQATKVERVHADKPNVPRGLTKYLTALHEELSSHMMKEEQILFPMIKQGMGRQATGPISVMESEHDEAGELVDVIKHVTQNVTPPPEACTTWKAMYNGINEMIDDLMEHISLENNVLFPRALAGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEXB2_HAEIF
Sequence: MQYGDQTTFKQSLAIQGRVINALLMREIITRYGRKNIGFLWLFVEPLLMTFFIVMMWKFIRADKFSTLNMIAFVMTGYPMAMMWRNASNRAIGSISANLSLLYHRNVRVLDTIFTRVLLEVAGASIAQILFMAVLVLIGWIDAPRDVFYMLMAWFLMAMFAFALGLIICAVAQQFDVFGKIWGTLSFVLLPISGAFFFVHNLPSQAQSIALWLPMIHGTEMFRHGYFGDTVVTYESIGFLVVSDLALLLMGLVMVKNFSKGIEPQ
What is the function of this protein?
May form an ATP-driven capsule polysaccharide export apparatus, in association with the BexA, BexC and BexD proteins.
What are the official names of this protein?
Capsule polysaccharide export inner-membrane protein BexB.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THBI_BOTJA
Sequence: EKFPAVNQKPQAAXL
What is the function of this protein?
Binds to thrombin and inhibits blood coagulant activity.  Does not inhibit the serine protease activity of thrombin or platelet aggregation activity.  May bind to the heparin recognition exosite.
What are the official names of this protein?
Thrombin inhibitor subunit 1, Thrombin inhibitor subunit I.
What are the subcellular locations of this protein?
Secreted.
Protein: DYR_STAAM
Sequence: MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMGRKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEMIDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVASSVEGKLDEKNTIPHTFLHLIRKK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: ARGA_SALTY
Sequence: MIKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHDNFSSIVSDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPIYHKNTRVTDAKALELVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFTIAQPLGVDDGVDYCHSGRIRRIDEDAINRQLDNGAIVLMGPVAVSVTGESFNLTSEEIATQLAVKLKAEKMIGFCSSQGVTNSEGGIISELFPNEAQARVEELEAQGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGSLLQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIQRDNMTIACAALYPFVEEKIGEMACVAVHPDYRSSSRGEVLLERVAAQARQMGLRKLFVLTTRSIHWFQERGFTPVDIELLPESKKKMYNYQRRSKVLMADLG
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_CHAVU
Sequence: MKLYEWLLQRVRKALKKAYEASKEIKTMKQDFSLYKKSDFFDTTSWENSFSYIDFELNKYKWIIKYSLFKYRVSVVFLLFLSPFEISHSKDSLYFNILHNKKIHMQLSWIKKVIDDIETWQKKKRDFFYLQQTKNKQKQKKFHLGILSNIDSIAYETIGFIPRSITRTLYRFKTELTGKTALILFREFRFAKYQALASIQYGFFLLLLPWIVTLLFKKLSLEYLMNVWWNKSSIQLFNASQKKIALKRFQNMEDIFWLDLITKETLENKSQYSISLKIHDMIISLVEIYTQKSIYTIIELITDFIGIFTITVILCIAKKRLTVLNSWLQELFYSLSDTMKAFFILLITDLCIGFHSPHGWEVLIELVWEHFGFVPNQYITSFFVSTFPVVLDTMVKYWIFRHLNRISPSIVVTYHSMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: Y1262_PEDPA
Sequence: MGKLDETMFFDFGDNKQNDVRETLKTVYDALEEKGYNPIDQIVGYLISGDPAYIPRLNDARNLIRKHQRDEIIEELVRYYLSEQIADSKKEEN
What are the official names of this protein?
UPF0297 protein PEPE_1262.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: IL10_MACNE
Sequence: MHSSALLCCLVLLTGVRASPGQGTQSENSCTRFPGNLPHMLRDLRDAFSRVKTFFQMKDQLDNILLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHDPDIKEHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVMNAFSKLQEKGVYKAMSEFDIFINYIEAYMTMKIQN
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPD_YERPY
Sequence: MSNFAVSLPEVIAVLPAAGIGSRMLADCPKQYLTVGGKTIIEHAIFSLLHHPRIQRVIVVIHPQDTQFSRLSVAQDPRISTVYGGDQRANSVMAGLQLAGQAEWVLVHDAARPCLHLDDLSRLLSITECSQVGGILAAPVRDTMKRAEPGIQAIAHTVDRQDLWHALTPQLFPLELLKLCLSRALREGVAVTDEASALEHCGYHPILVTGRSDNIKVTRPEDLALAEFYLTQRQSLNNDSL
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TM214_HUMAN
Sequence: MATKTAGVGRWEVVKKGRRPGVGAGAGGRGGGRNRRALGEANGVWKYDLTPAIQTTSTLYERGFENIMKRQNKEQVPPPAVEPKKPGNKKQPKKVATPPNQNQKQGRFRSLEEALKALDVADLQKELDKSQSVFSGNPSIWLKDLASYLNYKLQAPLSEPTLSQHTHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIATANLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAITYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPDSTLHTYFPSFLSRATPSCPPEMKKELLSSLTECLTVDPLSASVWRQLYPKHLSQSSLLLEHLLSSWEQIPKKVQKSLQETIQSLKLTNQELLRKGSSNNQDVVTCDMACKGLLQQVQGPRLPWTRLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLRSSGFLPASQQACAKLYSYSLQGYSWLGETLPLWGSHLLTVVRPSLQLAWAHTNATVSFLSAHCASHLAWFGDSLTSLSQRLQIQLPDSVNQLLRYLRELPLLFHQNVLLPLWHLLLEALAWAQEHCHEACRGEVTWDCMKTQLSEAVHWTWLCLQDITVAFLDWALALISQQ
What is the function of this protein?
Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis.  Required or the activation of CASP4 following endoplasmic reticulum stress.
What are the official names of this protein?
Transmembrane protein 214.
What is the protein family that this protein belongs to?
Belongs to the TMEM214 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GCSPB_THEON
Sequence: MFRQAKWDEPLIFELSRSGRVGYTLPKPIEDVEIRVPEKLKRKSPLNLPELSEPEVVKHYTRLSGMNYGVDSGIYPLGSCTMKYNPKINEEIAGHPGVAYVHPYQDERTIQGALKIMWELEGWLKEITGMDRFTLQPAAGANGEFTGVMIIRAYHLDRGETQRTEMLVPDSAHGTNPASAAMAGFKVIEIPSNENGTVDLEALENAVSERTAGLMLTNPNTLGIFEDEILEIAKIVHKAGGLLYYDGANLNAVLGKIRPGDMGFDIVHLNLHKTFSTPHGGGGPGSGPVGVKDFLKDYLPVPLVGYDEESGRYYLDYNVPKSIGKVKELYGNFAVMVRALTYLKIMGRDGLKEASEIAVLNANYLTQKLKGTRGYELPHKELRKHEVVFSAEPMKKETGVKALDVAKRLLDFGLHAPTIYFPLIVHEALMIEPTETVSREELDAYVEALKRISEEAYSNPELVKSAPHNTAVKRVDDVLAAKRPIITWRMYRELKEKGEVDI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: RL25_MICLC
Sequence: MSDQLKIKVTRRTDFGKGAARQARRAGLIPAVVYGHGQEPVHLLLPAQETTLAVRNPNALLTVVNEAGEEHLVLPKDIQRHAIKDTVDHLDLIEVRRGEKVVVEVTVQVEGEVAPGTEYVLDYVTVPVEADATDLPEAVTISVEGREAGDHVYAPDVQVPAGATLQLEDDIVIATVNEVVEQDLGDESVQEEQAAESAEGESEGSED
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RS26A_CANAL
Sequence: MPKKRASNGRNKKGRGHVKPVRCLNCARCVPKDKAIKRVTIRNMVEAAAVRDLSEASVYAEYALPKLYNKLHYCVSCAIHARIVRVRSRTDRKIRTPPQRKRFTSDRKVSPQDAAKKAN
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S26.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS26 family.
Protein: HTPX_BUCA5
Sequence: MTRIVLFLLTNLAVMLIFSLILFLTGIQSNTIYGLLIMSGLFGFSGSILSLILSKWIALRSVNGEIITHPRNEVESWLINTVRQQSIQKGIIMPQIAVYHATDINAFATGARRNSALIAVSTGLLENMTHHEAEAVIAHEISHIANGDMITMTLVQGVVNTFVIFISRFLSQIISNVMSSNRNENNTEEKNSFVYFLVSTFLELIFGILASIITMWFSRHREFYADASSAKMVGREKMIAALNRLKTSHEPQESDSMIAFCINGKSKSFLKLFASHPSLENRIEALYNQEYM
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERA_PSEP1
Sequence: MTDSNPTRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGDVQAIYVDTPGMHKANDKALNRYMNRNASAALKDVDVVIFVVDRTKWTDEDQLVLERVQYVTGPLIIAVNKTDRMEEKAELIPHLQWLQEQLPNAEVMPISAQQGHNLEALEAQIAKHLPENDHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGHVLHIHALILVERDGQKKIIIGDKGERIKRIGSEARKDMEVLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: THIC_SHEPA
Sequence: MSNRRETRAQAQQFIDNLKPLQHPNSEKVYLEGSRPDLKVGMRQIHQSDTLVAGDEANPVFEANPPLKVYDCAGAYSDPDANIDVRKGLEKFRENWIEERGDTVQLTSASSGFTQQRLADDGLDHLRFESLLPPRRAKEGKRVTQLHYARQGIITPEMEYIAIRENMAKSEVTDPILTQKDKGESFGAVIGEPITAEFVRQEIARGRAIIPLNINHPEAEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGVAEDLNWETFRDTLIEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLYEHFREICEICAAYDVSLSLGDGMRPGSIADANDEAQFSELETLGKLVKVAWEYDVQTIIEGPGHIPMNLIKENMDKQLEVCDEAPFYTLGPQTTDIAPGYDHFTSGIGAAMIAWYGCAMLCYVTPKEHLGLPNKDDVKQGLIAYKIAAHAGDVAKGHPSAQIRDNALSKARFEFRWEDQYNLGLDPETARAYHDESLPQESAKVAHFCSMCGPKFCSMKITQEVRDYAAAQEREAEARVIDIKSATEYDSYTGSESDTAKRASQREQGMAQMSAEFKAKGAELYHEASHKQPDVALED
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: AG19_COCIM
Sequence: MKFSLLSAIAAAVFVPFTSATPLASTTDLSYDTHYDDPSLALSGVTCSDGDNGMITKGYNTAGEIPNYPHVGGAFTVETWNSPNCGKCYKVTYNAKTIFLTAIDHSNSGFNIAKKSMDVLTNGRAEELGRIKVTYEEVASSLCGLK
What are the official names of this protein?
Heat-stable 19 kDa antigen, CS-AG.
What is the protein family that this protein belongs to?
Belongs to the cerato-platanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFB_XANOM
Sequence: MKFSENWLRSHVPIQATRDELAATLTAIGLEVEEVIPLGESLGQVVVARIVEAMRHPEADRLQVCSVDAGQGELLQIVCGAPNARPGLVAPLALVGAKIGELTITAAKLRGVASNGMLCSAKELGLDSDAAGLFELPDDAPVGQALAEYLGLPDASIEIKLTPNRADCFSVRGIAFDVAAACASEVVAFDAGAVAPVSTRTLAVELDAGKDAPRYCGRVIEGIDPAAKTPVWLAERLRRSGVRPVSLLVDITQYVMLELGQPMHAFDLDTLHGPIGVRRSCAGEQLALLDGRQVTLDDSFLTIADAGRPVALAGLMGGLDTRVTETTRNVFLESAYFDPAAIMGRGRKLGLHTDAGHRFERGVDSALPPQAIEVATRLVLELAGGTPGPVVHAQLPQHLPQPARILLRRARIARVLGIQIDDVDVVRMLRALGMQLDAVAEGWEVMAPSRRFDIAIEEDLIEDLARIHGYDRVPTTLPGGASRIAMPSETQLDELSVRRQLVARELQETINYAFVDAALLERWQLTNGLVPLANPLSAELAIMRPCLLPGLVATLGRNAARQAGRVRLFELGKVFAAAADAGAAPQESQHVAAAVCGDALALQWGEAARKVDFHDVKGDLMALAAASGAQLEFQPSTQPFGHPGRSADIYRDGVCIGWIGQVHPRLAKALDIDVDVIAFELQLGPLVQRTLPCAGELSRFPSVRRDLAFLVPDEVSWAAVSASVRTTVGPLLREVQLFDRYVGQGVAPGFKSLAMGLILQDNSRTLTDRDVDAVVTDVVAVIEREHRARIRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_LACLS
Sequence: MAVFEKVQDIIVDELGKEKEEVTLETSFEELDADSLDLFQIINDIEDEFDVEVDTEADMKTVADLVKYVENNK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.