PharMolix/UniProtQA huggingface dataset:
Protein: RECU_STRP8
Sequence: MVNYPHNLIRQKVSSVQKQTKQNKVDFANRGMSFEAAINATNDYYLSRQIAVIHKKPTPVQIVKVDYPKRSRAKIVEAYFRQASTTDYCGVYKGHYVDFEAKETRQKTAMPMKNFHLHQIEHMACVLHQKGICFVLLHFSTLKETYYLPAQALISFYQIDNGSKSMPIDYIRKNGFKVAFGAFPQVPYLNIIEQNFLGGDYN
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFCN_ECODH
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: MTNA_NATTJ
Sequence: MVSVKPLKFEDDELLLLDQRKLPGKEEYFTCKTYQDVHFAIKEMVCRGAPLIGAVGAYGVALACREFINESQEKFQQETKRAISELSSARPTAVNLFWALNKMNKLLGQVMEENTAPEDIYPIILNEAHKISDQELQRNYRIAEFGDQVISNGDKILTHCNTGALATTGYGTALGVIRQAHYNHKDIFVYVDETRPRLQGAKLTAWELKQEQLPFALIPDSSAAVLIKNGDIDVIFVGADRIASNGDTANKIGTFMLSILAKKYKVPFYVVAPVSTIDFQAKNGDDITIEERSSKEVTEIDGVRVAPTDIQVYNPAFDITPAENITGIITEKGIIGPNNREIMTIQE
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: Y1357_RICBR
Sequence: MIRNIIITISAILLLTSKGFADDTISNTSKKDTKTDITTQKILDEFYAYAGTIKPEIREEIQKYRVEIVNINKKKRELYDKLSKEAQNFLAKEQEYKQRLSSSSMATEDSKDNNTAKDNKDADKK
What are the official names of this protein?
Uncharacterized protein RBE_1357.
Protein: RS9_PARP8
Sequence: MIGNWNYGTGRRKSAVARVFIKAGKGDIVVNGKPIADYFSRETSLMIVRQPLELTNHGTTFDIKVNVSGGGETGQAGAVRHGITRALMDYDATLKPALSNAGFVTRDAREVERKKVGFHKARRRKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CP74A_ARATH
Sequence: MASISTPFPISLHPKTVRSKPLKFRVLTRPIKASGSETPDLTVATRTGSKDLPIRNIPGNYGLPIVGPIKDRWDYFYDQGAEEFFKSRIRKYNSTVYRVNMPPGAFIAENPQVVALLDGKSFPVLFDVDKVEKKDLFTGTYMPSTELTGGYRILSYLDPSEPKHEKLKNLLFFLLKSSRNRIFPEFQATYSELFDSLEKELSLKGKADFGGSSDGTAFNFLARAFYGTNPADTKLKADAPGLITKWVLFNLHPLLSIGLPRVIEEPLIHTFSLPPALVKSDYQRLYEFFLESAGEILVEADKLGISREEATHNLLFATCFNTWGGMKILFPNMVKRIGRAGHQVHNRLAEEIRSVIKSNGGELTMGAIEKMELTKSVVYECLRFEPPVTAQYGRAKKDLVIESHDAAFKVKAGEMLYGYQPLATRDPKIFDRADEFVPERFVGEEGEKLLRHVLWSNGPETETPTVGNKQCAGKDFVVLVARLFVIEIFRRYDSFDIEVGTSPLGSSVNFSSLRKASF
What are the official names of this protein?
Allene oxide synthase, chloroplastic, Cytochrome P450 74A, Hydroperoxide dehydrase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Plastid, chloroplast, plastoglobule.
Protein: RS6_BARBK
Sequence: MALYEHVFLARQDIAPQQVDELLKTYKNVIESHGGKVERTENWGLRSLAYRIRKNRKAHYVLINIDAPAAAIAEMERQMRINEDILRYITIRVEKHEKEQSAMLSRPDRDDFPGKDEERPRPSRRQYEDVVEGGVE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RS2_ECO81
Sequence: MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDALFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: WTF1_SCHPM
Sequence: MKNNYTSLKSSIDKEDELKSVHEIDLEKGLLPEYNSDEESTLPPYSDHARVSNPPNTHRENHSSGTTDNSSPFLIKLLISFTSIILFNAPAVCYLKYKDAFFKNYGAAEWTLIGFWCASSLIIFTFSWYFYETWTKAVGKGIKHFLKKWRNIPMAFSEVFLFNILVGSPRVTLRHISGERWGLKCSLADHIIFAILSILVFIVETVEPGSSKINIMKRLRGDNARDATQHVNEYTAVPLREMNPESEA
What is the function of this protein?
Acts as a suppressor component of the dual wtf meiotic drive system, and can suppress but not confer meiotic drive by compatible poisons (PubMed:32032353).  Wtf meiotic drive systems promote unequal transmission of alleles from the parental zygote to progeny spores by encoding a poison and an antidote from the same locus; the poison is trans-acting and forms toxic aggregates in all spores within an ascus, wherease the antidote is spore-specific and targets aggregates for degradation by the vacuole (By similarity).  Meiotic drive by wtf systems therefore lead to poisoning of all progeny that do not inherit the dual poison/antidote allele, or express a compatible antidote (PubMed:32032353).
What are the official names of this protein?
Meiotic drive suppressor wtf1.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: LEUD_CITK8
Sequence: MAEKFTQHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPEFVLNFPEYKGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDEEVDELFALVKANPGIKFEVDLEAQVVKAGDKTYSFKIDDFRRHCMLNGLDSIGLTLQHESAIAAYEEKQPSFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: GPMA_WIGBR
Sequence: MSIIKLVLMRHGSSIWNDQDRFTGWTDIDLSEKGKNEVKYAGKMLKSFGYSFNFAYTSLLKRAIHSLWVILKEINQSWIPVEKSWRLNERHYGALQGFSKYEIEKKYGKNQLNEWRRGFSISPPKINEKDNYFILNDKRYLNLKTKKLLPFSESLKSTIDRIMPYWDGNIFPRLQNKEKIIIVAHGNSIRAIIKILCNLNEKEIIKINIPTGIPLIYEFDYNMVFKKKYFLFDR
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PLBL2_CAEEL
Sequence: MTRLIRSKKQFLIRSLHSVFYYLGSLLHSTFEMNVFIGLLLATVVASQSSEGRDESYTYKQLCIVDDKPQVLDGFDCRNQVAVARWQNAVNTTGWTFLEVETKENYCPQLQAYSAGYLEGLLSKTVLTYHLKNAQEDYCKNFTGYCSRLSDFLTENQKWIQSSLETVAPDDLYWGAVNRTYHQVSGLIDAYEGREFKPRITYELHPILYLNLNGDFYDLEKKLNKTRDPAFEQTGGKCSGLIKVAPGNADLFISQVTMSGFQNMLRVIKLYKFGYDRQFYPGYASSFSSYPGLLYSSDDFALQTSGLAVIETTISVFNTSLFENTKPVGQLPTWIRAIVSNQLARDAREWCKLYSLYNSGTYNNQWAVLDYKKFKPNQPLPKNGLFYVLEQMPGKIVYSDLTWFVEKYSYFPSYNIPFFKEITEISGFIGQAAKMGDWFKWGASPRAKIFERDHGNVHDLDSLTALMRYNDYKNDEFSKCKCNPPYSAEAGISARGDLNPANGTYEFPGQGHVNHGALDYKGTNVELMKKLQFVAQGGPTWGKVPSFKWSEFDFKDKVNHVGHPDEWKFNTLVHKWETEINA
What is the function of this protein?
Putative phospholipase.
What are the official names of this protein?
Putative phospholipase B-like 2, LAMA-like protein 2, Lamina ancestor homolog 2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase B-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_SHEDO
Sequence: MAAMTVQLDIVSAEGGIYSGRVSHLQVTGSEGELGIMHGHAPLISKIKPGMARVTKQDGSEEVFYLSGGILEVQPASTSILADVVLRADDIDEKAAIEAKNRAEAHMVDAGSDFDYQAALIEIAKATAQLRVLETIKKNIAR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CARP6_CANAX
Sequence: MFLKNILSVLRFALLIDAAPVKRSPGFVTLDFNVKRSLVVPDDPTAESKRSPLFLDLDPTQIPVDDTGRNVGVDKRGPVAVKLDNEIITYSADITVGSNNQKLSVIVDTGSSDLWIPDSKAICIPKWRGDCGDFCKNNGSYSPAASSTSKNLNTRFEIKYADGSYAKGNLYQDTVGIGGASVKNQLFANVWSTSAHKGILGIGFQTNEATRTPYDNLPISLKKQGIIAKNAYSLFLNSPEASSGQIIFGGIDKAKYSGSLVELPITSDRTLSVGLRSVNVMGRNVNVNAGVLLDSGTTISYFTPSIARSIIYALGGQVHFDSAGNKAYVADCKTSGTVDFQFDKNLKISVPASEFLYQLYYTNGKPYPKCEIRVRESEDNILGDNFMRSAYIVYDLDDKKISMAQVKYTSESNIVAIN
What are the official names of this protein?
Candidapepsin-6, ACP 6, Aspartate protease 6, Secreted aspartic protease 6.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: BPAP_BOVIN
Sequence: DSELAGPRGARGPHGLSGPHGLSGLXGPXGYTGPIGMXGLTGLRREESEKVWLESKDGQELELVSSGSAQEELELVSSGSAQVSFASYLGASQPLPSELW
What are the official names of this protein?
Pregnancy-associated protein bPAP.
Protein: AAT_THEKO
Sequence: MFNVYEFFNRINEVRPESRLDAGQPDIPVRREIIEEAVESLRRGETGYTSTGGIRELRERIAEFEGVSADEVIVAPGAKILIAAEIASAKKVAVVSPRWNAYSLIARQFWREVEVIKTTLDERWIPRVEEIKADLIIINYPNNPTGRVLSGKEIRGLLDVAEENGVKVLSDEVYAELSFTRFTPARELYENVVTVKGFSKLYSMTGFRLGYAIGERNEIRRIQRFIESTVTCVPPFVQRAGVKALELRDELIKEVRRAYLERVRMASKMLRGFDFVEPEGAFYIFLRTPQDGMAFAERLLSRGVAVFPGMAFGDYPNFIRISLSGKGLERGLRVIREELECALESRATEGWEGSSRGVSAEGSR
What are the official names of this protein?
Aspartate aminotransferase, AspAT, Transaminase A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARI1_MOUSE
Sequence: MDSDEGYNYEFDEDEECSEEDSGAEEEEDDDEDEPDDDNLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED
What is the function of this protein?
E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3.  Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets.  The initial ubiquitin is then elongated by CDC34/UBE2R1 and UBE2R2.  E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes.  Plays a role in protein translation in response to DNA damage by mediating ubiquitination of EIF4E2, the consequences of EIF4E2 ubiquitination are however unclear.  According to a report, EIF4E2 ubiquitination leads to promote EIF4E2 cap-binding and protein translation arrest.  According to another report EIF4E2 ubiquitination leads to its subsequent degradation.  Acts as the ligase involved in ISGylation of EIF4E2.  In vitro, controls the degradation of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex member SUN2 and may therefore have a role in the formation and localization of the LINC complex, and as a consequence, may act in nuclear subcellular localization and nuclear morphology.
What are the official names of this protein?
E3 ubiquitin-protein ligase ARIH1, Protein ariadne-1 homolog, ARI-1, RING-type E3 ubiquitin transferase ARIH1, UbcH7-binding protein, UbcM4-interacting protein 77, Ubiquitin-conjugating enzyme E2-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Mainly cytoplasmic. Present in Lewy body.
Protein: PRMA_STRA5
Sequence: MNTWNELTVHVNREAEEAVSNLLIETGSQGVAISDSADYLGQEDRFGELYPEVEQSDMIAITAYYPDTLDIEAVKADLADRLANFEGFGLATGSVNLDSQELVEEDWADNWKKYYEPARITHDLTIVPSWTDYEAKAGEKIIKMDPGMAFGTGTHPTTKMSLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKDIYAYDLDDVAVRVAQENIDMNPGTENIHVAAGDLLKGVQQEVDVIVANILADILIHLTDDAYRLVKDEGYLIMSGIISEKWDMVRESAEKAGFFLETHMVQGEWNACVFKKTDDISGVIGG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCB2B_ORYSJ
Sequence: MVIKVPYVTAATTLFSFGLIFGFGHLRDSFRALLRLLFSSAAAADSPAGCNSKGYAPICVGKEDFYIRRFFRRVQDCFGRPIASKPDAWFDVVERYSTDSNKTLHCTTKTSKCLNLASFNYLGFAAADEYCTPRVIESLKKYSASTCSSRVDGGNTQLHIELEELVARFVRKPSAILLAMGYATNSAIIPALIGKGGLIISDSLNHNSIVSGARASGATIRVFEHNNPAHLEKLLREQISGGQPRTHRAWKKILVIVEGIYSMEGELCKLPEIISVCKKYKVYTYMDEAHSIGAVGKTGRGVCELLGVDPADVDIMMGTLSKSFGSSGGYIAASKEIIQHLKLTCPSHIYGTSMSPPAVQQVISAMKVILGEDGTDRGAKKIAQIRDNSNFFRSELQKMGFEVLGDNDSPVMPFMVYNPAKMPAFSRECLKQNVAVVPVGFPATPLLLGRIRICISASHSREDLIKGLEVISNVGDLVGIKYLPVEQEETTSVEKPKKL
What is the function of this protein?
Serine palmitoyltransferase (SPT).  The heterodimer formed with LCB1 constitutes the catalytic core (By similarity).
What are the official names of this protein?
Long chain base biosynthesis protein 2b.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: SP2SB_BACCR
Sequence: MAEVNVQKSSFFKEKKEESNTDFSLVKGALTENINRLEKLMNNSSSKYIQVKRTKENA
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Antitoxin that binds toxin SpoIISA and neutralizes its toxic activity.  Upon coexpression with SpoIISA in E. coli normal growth is restored.
What are the official names of this protein?
Stage II sporulation protein SB, Antidote protein SpoIISB, Antitoxin SpoIISB.
What is the protein family that this protein belongs to?
Belongs to the SpoIISB antitoxin family.
Protein: CH601_CHRVO
Sequence: MAAKEVRFHDNARERIVNGVNVLADAVKVTLGPKGRNVLLARSFGAPHITKDGVSVAKEIELKDPFENMGAQMVKEVASKTADVAGDGTTTATVLAQAIVQEGMKYVASGMNPMDLKRGIDKAVHAVIKELQTLSKPVTNSKETAQVAALSANSDEAIGKIIADAMDKVGKEGVITVEDGKSLDNELAVVEGMQFDRGYLSPYFITDPEKQTAVLEDPLVLLYDKKISNIRDLLPVLEQVAKAGKPLLIVAEDVEGEALATLVVNSMRGILKVAAVKAPGFGDRRKAMLEDIAILTGGTVIAEETGLTLEKAGLAELGSAKRVEIGKENTTIIDGAGDKAKIDARVQAIRAQIDAATSDYDREKLQERVAKLSGGVAVIRIGAATEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALLRARAHIKELKGDNPDQDAGIQIVLRALEAPLRAIAANAGDEPSVIVNKVLEGKGNHGYNAASGQFGDLVEMGVIDPTKVTRTALQNAASIASLILTTDATVAEAGQDSKAKAPAELDY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAP1_CRIFA
Sequence: MLRVSVRSLVRKASSKAGSKAAVPAAAAAASAPLSPATSAASARAVPPVGESRVSIPPIPGVAAPRSHRAAAAPAKKAAAPKAAKAKTPAKASRKIKKAASKPSAPKQAAGKMRKAAGKAQRKIKAAARKAAPKKMAKSFGKKGAAKKAHK
What is the function of this protein?
Histone H1-like DNA-binding protein involved in the organization and segregation of kinetoplast DNA (kDNA).  The mitochondrial DNA of kinetoplastid protozoa consists of about 5,000 minicircles and 20 to 30 maxicircles.  These circular DNAs are held together by catenation into a highly organized compact disk structure referred to as a kinetoplast DNA (kDNA) network.  Binds preferentially to a specific fragment of minicircle DNA and is able to compact kDNA networks through DNA charge neutralization and condensation (By similarity).
What are the official names of this protein?
Kinetoplast-associated protein 1, Histone H1-like protein p21.
What is the protein family that this protein belongs to?
Belongs to the KAP family.
What are the subcellular locations of this protein?
Mitochondrion matrix, kinetoplast.
Protein: NIFH_AZOPC
Sequence: MRKIAIYGKGGIGKSTTTQNTVAGLVEMGRKVMVVGCDPKADSTRLLLHGLAQKTVLDTLRDEGEDVELEDVMKKGFKDTSCVESGGPEPGVGCAGRGIITSINLLEQLGAYDDDKQLDYVFYDVLGDVVCGGFAMPIRDGKAQEVYIVCSGEMMAMYAANNICKSIHKFGKVGDVRLGGLICNSRKVDNEANMIGEFAKKLGTQMIHFVPRDNMVQHAEINRKTVIDYAPDHSQADEYRTLASKIDNNTMMVIPNPLSIQELEDLLIGFGIMN
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.
What are the official names of this protein?
Nitrogenase iron protein, Nitrogenase Fe protein, Nitrogenase component II, Nitrogenase reductase.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: TIM21_ASPFU
Sequence: MMSPHLLPSTSIPKASAALLLRPAFPRMTTLTRFYATQSDLGGGSGSKATPRRRNVTVLSDDGRYEWGELSGREKVARATQQSLNFLVIVAGAVLTGGVFYLLYTEVFSPNSRTWQFEKAVQRIKDDPRCTDLLGDRREIKAYGESTGSRWERNRPIATSMFKDRQGREHMKMHFHVEGPLNSGIVIVHMMKPLDKDEWEYLLLALDVKGHSRVILEQAQEKPGVAKALKIFGIQWR
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Required to keep the TOM and the TIM23 complexes in close contact.  At some point, it is released from the TOM23 complex to allow protein translocation into the mitochondrial matrix (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim21.
What is the protein family that this protein belongs to?
Belongs to the TIM21 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: FLVF_ASPFN
Sequence: MEGLRRHSVMLDCKLWKDDPIYFFKTLPPYISKYAQRADDASIQAQIDVFGKDDVGAMPGALGPRGNFAAVTFAESFPDRVAMLAYLNEVLSFYECFEKQMTEMLDATLYANPVPKDPKYDNPVWQANYKNTMTKWPKILENLDPKLGPKCVKSLVALVEGTDMEPKMAHYKTMKEYALDRTNYIAWPVACDNAEFGSQLNLTQDQLDSVRDIFLPLWTHSCYVYDYYHYDKEAEIHSTYGKGRSMINSIPLLNRLKGLSVEEAKAWLKQRCFELEKEYLQRKEDYFSENPVEAVPVDLRRWFLSQEDLATGFAIWCATTYHNHPPFGEGYAAPYEKRRKEGALWFEKVTESDQLMTGGFEVRYAN
What is the function of this protein?
Terpene cyclase-like protein; part of the gene cluster that mediates the biosynthesis of flavunoidine, an alkaloidal terpenoid with a tetracyclic cage-like core connected to dimethylcadaverine via a C-N bond and acylated with 5,5-dimethyl-L-pipecolate (PubMed:31885262).  The tetracyclic core is synthesized by the terpene cyclase flvE and the cytochrome P450 monooxygenase flvD (PubMed:31885262).  The terpene cyclase flvE catalyzes the cyclization of farnesyl pyrophosphate (FPP) to form (1R,4R,5S)-(+)-acoradiene and the cytochrome P450 monooxygenase flvD is then responsible for oxidative conversion of (1R,4R,5S)-(+)-acoradiene into the tetracyclic cage present in the final product flavunoidine (PubMed:31885262).  In parallel, the N-methyltransferase flvH dimethylates L-lysine to give N,N-dimethyl-L-Lysin which is decarboxylated by flvG to afford dimethylcadaverine (PubMed:31885262).  The terpene cyclase-like protein flvF is the enzyme that attaches the dimethylcadaverine precusor at the C-7 of the tetracyclic cage to yield pre-flavunoidine (PubMed:31885262).  The cytochrome monooxygenase flvC hydroxylates the C-10 position of pre-flavunoidine whereas the NRPS flvI acylates the terpenoid core at the hydroxylated C-10 with dimethylpipecolate to yield final flavunoidine (PubMed:31885262).  The bifunctional enzyme flvA and the dehydrogenase flvB are responsible for the synthesis of the dimethylpipecolate precursor (PubMed:31885262).  The PLP-dependent lyase domain of flvA might use L-O-acetyl-homoserine and alpha-keto-isovalerate to form an intermediary ketone that can cyclize intramolecularly to yield an imine (PubMed:31885262).  The imine can be reduced by flvB to yield the 6-carboxylated pipecolate (PubMed:31885262).  The C-terminal alpha-KG-dependent oxygenase domain of flvA is then proposed to catalyze the decarboxylation to yield dimethylpipecolate (PubMed:31885262).
What are the official names of this protein?
Terpene cyclase-like protein flvF, Flavunoidine biosynthesis cluster protein F.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: ATPF1_AGRFC
Sequence: MAFDASFFALVGLVLFFVLIAYLKVPGMLSKSLDERAQNIQDELAEAKRLREEAQHLLAEYQRKRKEAEAEAAGIVAAAEREAAALTEEAKQKTEEFVARRTALSEQKIKQAEEDAIGAVRAAAVDIAIAASEKLLAEKTTAAAKAKLFAATIGEVKSKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MTC6_YEAST
Sequence: MWILIYLFIIWSSLRTWVTAVDSTTTVGDDLNETVSASVWPTMSPQMTVAFRSQRDVMGNLTIDQLPYVGLNLRRVLLNNETSMVNEGNNTRLLTLFKSMLSSEANAFVLDLEQYNNDLRVVDTTLLFSDVLTALQSFIFSTQNNLYANIIVLLLNISAPELDSTEYRHQNQTLNTTYILDKNLGNSFIYKPTDLQSDRAKNNTWNIYGKSSIDGWPTLGSVLYEQKKRLVIGELTDFFNETTAPYIFPHDVFHYEQGNSTLDCPSTVEGLTDLSSIHWRFLDSLFNSVDIKEYISCGLSPIISNSAYVNNVTQLADIIHEGSVWSWDSDQPSVTQSTSKSGSSSGTLEAYNCVLLYYFANNETVTWRVGNCYNSNIGLCRYENMAFRWLVRSNKATYFDFDSYQGSKCPDQYSFNIPRSPLEQRSFIAYMRNSSFSDTQIWIDLNSISVSNCWVSGGPYASCPYEKVISRRNFVTMMVPASVCSFALLCIVVYLSVLRVPIYDNRKNWRRVINKISKSELEGVPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: EXBD_AQUAE
Sequence: MIIVRSMEEKEISSMNVIPLVDIMLVLLTIVLTTATFIAKGEIPVELPEAKSGKAVQPQESVVITITKEGKIYLKSREVSYEELKEFLKTLNRQTPVEINADKNAKLENFVKVFDLLNQYGFKNVNLLVKKE
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
What are the official names of this protein?
Biopolymer transport protein ExbD.
What is the protein family that this protein belongs to?
Belongs to the ExbD/TolR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.