PharMolix/UniProtQA huggingface dataset:
Protein: RS17_POLNA
Sequence: MTEAKKSLKRTLIGKVVSDKRAKTVTVLVERRVKHELYGKIVSLSSKYHAHDEKGEFKTGDVIEITESRPISKTKNWVVTRLVQKAEIV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CTRA_BRUA1
Sequence: MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA
What is the function of this protein?
Component of a regulatory phosphorelay system that controls B. abortus cell growth, division, and intracellular survival inside mammalian host cells.  This signaling pathway is composed of CckA, ChpT, CtrA and CpdR.  CtrA is a response regulator substrate of ChpT.  When phosphorylated, directly regulates the expression of ccrM.  Is also probably involved in the transcriptional regulation of rpoD, pleC, minC and ftsE genes.
What are the official names of this protein?
Cell cycle response regulator CtrA, Cell cycle transcriptional regulator A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOB1_BOVIN
Sequence: MAPVEHVVADAGAFLLDAALQDIGKNIYTIRNVISEIRDKATRRRLAVLPYELRFKEPFPEYVRLVTEFSKKTGDYPSLSATDIQVLALTYQLEAEFVGVSHLKQEPEKVKVSSSIQHPETPLHVSGFHLPSKPKPPRETVEHRHPASEPEDLEFSSFMFWRNPLPNIDCELQELLMDGGEDVPNEEEDEENGLDERQDEDSDDDGGGWITPSNIKQIQQEMKQCAVPKDVRVGCVTTDFAMQNVLLQMGLHVLAVNGMLIREARSYILRCHGCFKTTSDMSRVFCAHCGNKTLKKVSVTVSDDGTLHMHFSRNPKVLNPRGLRYSLPTPKGGKYAINPHLTEDQRFPQLRLSRKARQKTDVFAPDYVAGVSPFAENDISSRSATLQVRDSTLGAGRRRLNPNASRKKFVKKR
What is the function of this protein?
May play a role in mRNA degradation (By similarity).  Endonuclease required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits (By similarity).
What are the official names of this protein?
RNA-binding protein NOB1.
What is the protein family that this protein belongs to?
Belongs to the NOB1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_HELPH
Sequence: MRRRKAPVREVLGDPVYGNKVVTKFINKMMFDGKKSVAEKIIYKAFNKIEEKSGEKGIEVFEKALERVRPLVEVRSRRVGGATYQVPVEVRASRQQSLSIRWILEATRKRNERMMVDRLANELMDAASDKGAAFKKKEDVHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RUVB_XANC8
Sequence: MTEQRTIASSATREDEAADASIRPKRLADYLGQQPVRDQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGVNLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTPDGAAEIARRARGTPRIANRLLRRVRDFAQVKAAGHIDLAVAQAAMQMLKVDPEGFDELDRRMLRTIVDHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVTPKAYLHLGLKPPRDRAPAIGEPGDLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: RRAA_SHEDO
Sequence: MEYNTSELCDMYIDVVDVVEPMFSNYGGCSSFGGAISTVKCFEDNGLIADALQEDGEGKVLLVDGGGSLRRALIDASIAQIAVNNNWEGIIVYGSVRDVDALEELDLGIQALASIPVGAEGNGVGEIELPVNFGGVTFLPGDHIYADNTGVILSPEPLDID
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_BACCR
Sequence: METTVRKQKKNLETKKPSIYSLQLHEMQDWLKEQGEPKFRAGQIFDWLYKKRVKNYEDMSNLSKGLRDKLSNSFDITTLKTLVKQTSSDGTIKFLFQLYDGYSIETVLMRHEYGNSICVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVAQVVEVQRALDETEERVSSLVVMGIGEPFDNYDNLMGFLRIINHEKGLHIGARHMTVSTSGIIPKIYKFAEEDLQINFAISLHAPNSELRSKLMPINRAYKLPDLMEAIKYYVNRTGRRITFEYGLFGGENDQVEHAEELAALLKGVKCHVNLIPVNYVPERDYVRTPREQIFLFEKTLKDRGVNVTIRREQGHDIDAACGQLRAKERKEETR
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOB_VIBVY
Sequence: MKRAFILVLDSFGIGATADAKEFGDVGSDTLGHIADQCEQGLANNDQRQGALRLPNLSKLGLAMAHKESTGRFAPGLDADAEIIGAYGHAAELSSGKDTPSGHWEIAGVPVLFEWGYFTDKANSFPKELTDRILARAGIDGFLGNCHASGTQVLDDLGEEHMKTGQPIFYTSADSVFQIACHEETFGLDRLLELCQIAREELADYNIGRVIARPFIGPGKGQFERTGNRRDLSVEPPSATVLQKLAEEKQGQVVSIGKIADIYANCGITKKVKATGIPALFEATLEQIKQAGDNTIVFTNFVDFDSAYGHRRDVAGYAAALEYFDGRIHEVMELMQEDDILILTADHGCDPTWPGTDHTREHIPVLVYGQKVPAGSLGRRETFADIGQTLASYFGTSPMDYGKNFL
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_CLOAB
Sequence: MEINIREDAFIVEINILKCHGTGNDFILIDEYNNNYNLDDETRRDIAIQACNRAKFIGGDGILFVQKSDICDAKMRIFNADGSEAEMCGNGLRCVGRYVIEMLNKESVEIETLKSKYWVKLQEDIYEGVKTVKIDIKSVSLDVKTLPLNYKKEKLIFDKIPELSDEFDFTAVSITNPHLIAIVNNIDSDKLVEIGKKGNSTKSVLPQGVNVSFVKVIDSSNIYVKTYERGVGLTKSCGTAMTASSIVSCIGEKVQFDNAINVYNDGGAIKTIVHKDSNGNYSVDFIGNATFIFEGTMELDKRKIEQFTIDESKFEKETNSYNEFFEYTRKNCK
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAA1_BACLD
Sequence: MIQAKTHVFWFVTGSQHLYGEEAVQEVEEHSKMICNGLNDGDLRFQVEYKAVATSLDGVRKLFEEANRDEECAGIITWMHTFSPAKMWIPGLSELNKPLLHFHTQFNRDIPWDKIDMDFMNINQSAHGDREYGFIGARLGIPRKVIAGYWEDREVKRSIDKWMSAAVAYIESRHIKVARFGDNMRNVAVTEGDKIEAQIQLGWSVDGYGIGDLVTEINAVSEQSLSELISEYEELYEWPEGEAARESVKEQARIELGLKRFLSSGGYTAFTTTFEDLHGMKQLPGLAVQRLMAEGYGFGGEGDWKTAALVRMMKMMAGGKETSFMEDYTYHFEPGNEMILGSHMLEVCPSIAEHKPRIEVHPLSMGAKDDPARLVFDGIAGPAVNVSLIDLGGRFRLVINKVEAVKVPHDMPNLPVARVLWKPQPSLRTSAEAWILAGGAHHTCLSYQLTAEQMLDWAEMSGIEAVLINRDTTILNLRNELKWSEAAYRLRKF
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: ORC4_BOVIN
Sequence: MSSRKSKSSNLIQADYISQVQRILRERFCHQSPHGNLFGVQVQYKHLIELLKRTAIHGESNSILIIGPRGSGKTMLINHALKELMEIEGVSENILQVHLNGLLQINDKIALKEITRQLNLENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLLDISQSAQTPVVIIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFSFPQYLKIFKEQLSLPSVFPEEIFAEKWNENVQSLSEDRSVKEVLQKHFNVSKNLRSLHMLLMLALNRVTPSHPFITAADLMEANQLCSMDSKGNIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRKAHSVYNFEKPVVMKAFEHLQQLELIRPMERTSVNAQREYQLMKLLLDNTQIMNALQKYPNCPTDVRQWATSSLSWL
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.  Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 (By similarity).
What are the official names of this protein?
Origin recognition complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the ORC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DBP5_SCLS1
Sequence: MSESKSTSWADEVASPSTEKNEESSLEDAQVDGATEPLGGGTLQDGQYEVEVKLSDIQGDQTSPLYSVDTFEQLGIDASILKGLYAMNFKKPSKIQEKALPLLLGNPPTNMIAQSQSGTGKTAAFVITILSRLDFSKPTTPQALCLAPSRELARQIEGVVRSIGQFVEGLSVQAAIPGAVERNARVNAMVIVGTPGTVMDLIKRKSIDASQMKVLCLDEADNMLDQQGLGDQCLRVKSMIKVEQILLFSATFPDEVYGFAQQFSPRANEIKLKRDELTVSGIKQMFMDCPNEVGKYEILVKLYGLMTIGSSIIFVKRRDTASHIAERLTAEGHKVAAIHGAFEGAERDTVLEDFRQGKAKVLITTNVLARGIDVQSVSMVINYDIPMKGRSDFEPDPETYLHRIGRTGRFGRVGVSISFVFDRKSYDALNKIAHHYNIDLIKLNQDDWDETEEIVKKVIKSSRAGTNLRA
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: PPA_SCHCO
Sequence: NAPWAQIDEV
What are the official names of this protein?
Acid phosphatase.
Protein: ARLY_CLOBJ
Sequence: MKLWGGRFKEEESKLMEDFNSSLSFDKKLYYEDIKGSIAHVKMLTNQNIIKEEEKEKILLGLEEILKEIDEGILKIEGDYEDIHSFVEINLINKIGNVGKKLHTGRSRNDQVALDMKLYAKKSTEEVIECLKELMDSLIKVGNENNYIMPGYTHLQRAQVVTFRYHLLAYFEMFKRDEKRLENALEILNESPLGSGALAGSTYNIDREYTAKLLGFRKPVDNFLDGVSDRDYIIELISKFSIIMMHLSRLSEELILWSSSEFRFIQIGDAYSTGSSIMPQKKNPDGAELIRGKIGRVYGDLISILTVMKSLPLAYNKDMQEDKEPFFDAKDTVISCLKVMEGIISTLKVNKENLMKSVKKGFLNATEAADYLVNKGMAFRDAHKVIGEVVIYCEDKNSAIEDLSLEELKQFSDLFCEDIYEFIDYKNSINKGIKKEMGYF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUS4_PONAB
Sequence: MAAVSMSVALRQTLWRRRAVAVAALSVSRVPTRLLRTSTWRLAQDQTQDTQLITVDEKLDITTLTGVPEEHIKTRKVRIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWASTADPLSNMVLTFRTKEDAVSFAEKNGWSYDVEERKVPKPKSKSYGANFSWNKRTRVSTK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial, Complex I-18 kDa, CI-18 kDa, NADH-ubiquinone oxidoreductase 18 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=The interaction with BCAP31 mediates mitochondria localization.
Protein: TDR10_HUMAN
Sequence: MSWNISHPQLSDKLFGKNGVLEEQKSPGFKKRETEVYVGNLPLDISKEEILYLLKDFNPLDVHKIQNGCKCFAFVDLGSMQKVTLAIQELNGKLFHKRKLFVNTSKRPPKRTPDMIQQPRAPLVLEKASGEGFGKTAAIIQLAPKAPVDLCETEKLRAAFFAVPLEMRGSFLVLLLRECFRDLSWLALIHSVRGEAGLLVTSIVPKTPFFWAMHVTEALHQNMQALFSTLAQAEEQQPYLEGSTVMRGTRCLAEYHLGDYGHAWNRCWVLDRVDTWAVVMFIDFGQLATIPVQSLRSLDSDDFWTIPPLTQPFMLEKDILSSYEVVHRILKGKITGALNSAVTAPASNLAVVPPLLPLGCLQQAAA
What are the official names of this protein?
Tudor domain-containing protein 10.
Protein: MIAA_STAHJ
Sequence: MSDINKPFLVVIVGPTASGKTELSIELAKQINGEIISGDSMQVYKQMDIGTAKVTNEEMDGIPHYMIDILNPDDSFSVYDFKLRAQALIEDITSRGKIPIIAGGTGLYIQSLIYDYPFDDETVSKEVEQKTQLQLQKLEPLTNQEVHDYLATFDPQSAKDIHPNNRKRVLRAIEYYLNTKKLISSRKKVQQFTENYDTLLIGIEMSRKTLYSRINKRVDIMLGHGLFNEVKNLVEQGYESTQSMQAIGYKELVPVVNGELSIDQAVETLKQHSRQYAKRQLTWFKNKLTVQWFNRETMSLQMMLDEITTQINKRSSKHDCKPQHPRSSTREL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: EPMA_VIBPA
Sequence: MQTNWQPTASIEQLRQRATLIAAIRQFFAERQVMEVDTPAMSHATVTDIHLHTFQTEFVGPGYADGSKLFFMTSPEFHMKRLLAAGSGCIYQINKAFRNEENGRYHNPEFTMLEWYRVGFDHHKLMDEMDDLLQLVLKCGAAQRMTYQQAFIDVLGVCPLEGSMTELKAAASKLGLSDIAEPEEDRDTLLQLLFSVGVENKIGQDVPAFVYDFPASQAALAKINPQDHRVADRFEVYFKGIELANGFHELDNPKEQLARFEQDNAKRIEMGLKPQPIDYHLISALEAGLPDCAGVALGIDRLIMLALGCDHIDQVTAFPFPIA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P).  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: RL15_FRATF
Sequence: MKLNTLAPAAGSKSAPKRLGRGIGSGLGKTSGKGHKGQKARSGGYHKVGFEGGQMPLQRRLPKFGFPSASKRYVAEIRLHELNNVVADEVTLDTLKDFGLIRKDIKTVKVIASGEIQKAVSLKGIACTKGAKEAIEKAGGKVE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PBP2_NEIMB
Sequence: MLIKSEYKPRMLPKEEQVKKPMTSNGRISFVLMAIAVLFAGLIARGLYLQTVTYNFLKEQGDNRIVRTQTLPATRGTVSDRNGAVLALSAPTESLFAVPKEMKEMPSAAQLERLSELVDVPVDVLRNKLEQKGKSFIWIKRQLDPKVAEEVKALGLENFVFEKELKRHYPMGNLFAHVIGFTDIDGKGQEGLELSLEDSLHGEDGAEVVLRDRQGNIVDSLDSPRNKAPKNGKDIILSLDQRIQTLAYEELNKAVEYHQAKAGTVVVLDARTGEILALANTPAYDPNRPGRADSEQRRNRAVTDMIEPGSAIKPFVIAKALDAGKTDLNERLNTQPYKIGPSPVRDTHVYPSLDVRGIMQKSSNVGTSKLSARFGAEEMYDFYHELGIGVRMHSGFPGETAGLLRNWRRWRPIEQATMSFGYGLQLSLLQLARAYTALTHDGVLLPVSFEKQAVAPQGKRIFKESTAREVRNLMVSVTEPGGTGTAGAVDGFDVGAKTGTARKFVNGRYADNKHIATFIGFAPAKNPRVIVAVTIDEPTAHGYYGGVVAGPPFKKIMGGSLNILGISPTKPLTAAAVKTPS
What is the function of this protein?
Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
What are the official names of this protein?
Probable peptidoglycan D,D-transpeptidase PenA, Penicillin-binding protein 2, PBP-2.
What is the protein family that this protein belongs to?
Belongs to the transpeptidase family. FtsI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HIS1_CLOB6
Sequence: MKKVKIALTKGRLEKKAIEIFKAININTRELEDKGRKLIFNCENEEYNIELFLVKAKDVETYVEYGAADIGIVGKDTLMETDKEFYEVLDLNMGKCKFAVAALPSFKLDQGYNRKKIATKYPNIAREYFRKKCMDVELIKIEGSVELGPIVGLADAIVDIVETGNTLRENGLAVVEDICEISARMIVNKASMKTKKDEVIKIVENISEVIR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_STRTD
Sequence: MITQRQNAILNLIVEMFTRTHEPVCSKALQDSIDSSSATIRNDMAKLEKMGYLEKAHISSGRMPSRAGFQYFVANSLNLDTIDEQDVYQVVKAFDFEAFKLEDILDAAAKLLAEMTGCTAVIQDVEPTKQRLTGFEIVQLSNHDALAVLTLDESKPVTVQFAIPKNFLSSDLEIFHKLVQGRFLGNTVLDIHYRLRTETPQIVQKYFKITDNVLDLFDYIFSHLFKELIFIEGKVASLAYADLKTYQFLDNPQHVALALRSAISDDEVTKISVAESTEEALENVTVMSHKFLIPYRGTALMHVIGPIEMDYRRMVSLVNVISRVLVMKLTDYYRYLNSNHYEVFLSRNVLKNIERGECLD
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SEPF_SYNY3
Sequence: MILTKLKDFVGISEHDEYEEDYDEEMEFPQSVASQPPAEEVAPPPRISREPLSLNNETSIGTGVRNNVIGMPGINNSVAEVVVVEPHSFDEMPQVIQTLRERKSVVLNLNVMDPEEAQRAVDFVAGGTFAMDGHQERIGESIFLFTPNCVKVSSLAGRSQESNETSSSVSSDNFPTWGYETSRLAQ
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: UVRB_CLOAB
Sequence: MGTFKINSAFKPTGDQPQAIASIVNGIKNNNKWQTLLGVTGSGKTFTMANIIEKVQKPTLVIAHNKTLAAQLCSEFRDFFPDSSVEYFVSYYDYYQPEAYVAQTDTYIEKDASINDEIDKLRHSATSALFERRDVIVVASVSCIYGLGNPEEYKKLSISLRTGMNKDRDEILEKLVEMQYERNEINFVRGTFKVKGDTIDIFPAGSTSSAIRVELFGDEIDKIKEFDVLTGNTIKTLKHTVIFPASHFATSSDKIEEAIKQIEIELEERLRELNSEDKLLEAQRLKQRTNFDIEMMREVGYCTGIENYSRIMDGRQKGEPPKTLIDYFPDDFLMFIDESHVTLPQVKAMYGGDRSRKNSLVDYGFRLPSAYDNRPLKFDEFEEKINQIVFVSATPSNYELDHSENIAEQVIRPTGLLDPEIEVRPTKGQIDDLYSEIKNTIQNGFRILVTTLTKKMAEDLTDYLKDLGIKTTYMHSDIDTLERMKIIKDVRTGEFDVLVGINLLREGLDIPEVALVAILDADKEGFLRSERSLIQTIGRAARNSESRVIMYGDKITDAMGKAISETKRRRKIQIEYNEKNGIKPTTIKKAVRDVIGISEVAEGKTEYKSMDEAVKADNKNIDKLIKEFEKEMKEAAKELQFEKAAYFRDKVNELKKKLNENEEVIK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCE3_BRANA
Sequence: MASSLKKLITSFLLFFFYTIIVASSEPSCRRYKSIISFGDSIADTGNYLHLSDVNHPPQAAFLPYGETFFSVPTGRDSDGRLIIDFIAEFLGLPYVPPYFGSQNVSFEQGVNFAVYGATALDRAFFIEKGIVSDFTNVSLSVQLNTFKQILPTLCASSSRDCREMLGDSLILMGESGGNDYNYPFFEDKSINEIKELTPLIIKAISDAIVDLIDLGGKTFLVPGSFPVGCSAAYLTLFQTAKEKDYDPLTGCLPWLNDFGKHHDEQLKTEIRRLRKLYPHVNIMYADYYNSLYRLYQKPTKYGFKNRPLAACCGVGGQYNFTIGEECGYEGVGYCQNPSEYINWDGYHITEAAHQKMAHGILNGPYATPAFNWSCLDAASVDNESSFGS
What is the function of this protein?
Sinapine esterase that catalyzes that hydrolysis of sinapine, releasing choline and sinapate.  Sinapine (O-sinapoylcholine) is the predominant phenolic compound in a complex group of sinapate esters in seeds of oilseed rape (B. napus).  Sinapine has antinutritive activity and prevents the use of seed protein for food and feed.  Shows broad substrate specificity towards various other choline esters, including phosphatidylcholine.
What are the official names of this protein?
Sinapine esterase, BnSCE3, Lipase 2, BnLIP2.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: CATZ_MOUSE
Sequence: MASSGSVQQLPLVLLMLLLASAARARLYFRSGQTCYHPIRGDQLALLGRRTYPRPHEYLSPADLPKNWDWRNVNGVNYASVTRNQHIPQYCGSCWAHGSTSAMADRINIKRKGAWPSILLSVQNVIDCGNAGSCEGGNDLPVWEYAHKHGIPDETCNNYQAKDQDCDKFNQCGTCTEFKECHTIQNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATEMMSNYTGGIYAEHQDQAVINHIISVAGWGVSNDGIEYWIVRNSWGEPWGEKGWMRIVTSTYKGGTGDSYNLAIESACTFGDPIV
What is the function of this protein?
Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity (By similarity).  Capable of producing kinin potentiating peptides (By similarity).
What are the official names of this protein?
Cathepsin Z.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: TCTP_DROPS
Sequence: MKIFKDIITGDEMFADTYKIKLVDDVVYEVYGKLISREGSEIKLEGANASAEEADEGTDTNVESGVDVVLNHRLVECFAFGDKKSYTLYLKDYMKKVLAKLAEKSPDQVDVFKTNMNKAMKDILGRFKELQFFTGESMDCDGMVALVEYREIDGQSIPVLMFFKHGLEEEKC
What is the function of this protein?
Involved in calcium binding and microtubule stabilization.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.