PharMolix/UniProtQA huggingface dataset:
Protein: RK24_GRATL
Sequence: MKMKKTNIKMHVKRGETVQIISGREKGKIGKIIKVLPKSSQVIIDNLNIATKHLKAQKEGDSGQIIRIEKPIHSSNVIQYKLDSNTSIKDRV
What is the function of this protein?
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L24, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UVRC_METBU
Sequence: MRPDISNIPELPGVYLMKDISDNIIYIGKAKSLKKRVSQYFQSSKNHSSKTRAMVRKIADVDYIVTESEVAALILEANLVKKNRPHYNIDLKDDKRYPYVKVTVNTKFPKIFITRRRLMDGALYFGPYTNVKPVRQTLDMISQIFRIKRCNRRVDGKGKRACLNYHIDRCYAPCNGSITPEEYRNNVMEAVKLFKGETSGTIKELQEKMNIHAIAQEYESAAVIRDQIDALKSLSRQQTATAGNDDSDIIATASDDETVFVQIFYIRDGNMVGKADMSLSWGDATGNIARVTEEFIKQYYQDAPVPPEILVQYPIPEKELVIKWLSEKAARSVQIQVPQRGNKKRLMEMAEQNAQMTLEQSHLKQSDKEQALQALLQLRDALALSTLPAHIEGFDISNISGTDAVGSMVVFENGLPANSKYRHFNIKTVKGIDDFAMMAEVVKRRYTHQKAEKDKLPDLILIDGGPGQVSAAMGSLKELQLDIPLVGLAKRFEHIIVPKDGTDEVVILPHTSEALKVLMRVRDESHRFAVSSHRRRRTARLSHSELDTIPGIGASRKKALLNHFSSIEQIRHASVEELTAVEGISKGLAERIVAHFNKERVENQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX6_MOUSE
Sequence: MVHINELPENILLELFIHIPAPQLLRNCRLVCRLWRDLIDVVSLWKRKSLREGFFTKDRCEPVEDWKVFYILCSLQRNLLRNPCAEENLSSWRIDSNGGDRWKVETLPGSCGTSFPDNKVKKYFVTSFEMCLKSQMVDLKAEGYCEELMDTFRPDIVVKDWVAPRADCGCTYQLRVQLASADYIVLASFEPPPVTFQQWNDAKWQEISHTFSDYPPGVRHILFQHGGQDTQFWKGWYGPRVTNSSIIISHRTAKNPPPARTLPEETVVIGRRRRASDSNTHEGFFWQGLWQRLRR
What is the function of this protein?
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes.  Involved in DNA damage response by specifically recognizing activated CHEK1 (phosphorylated on 'Ser-345'), promoting its ubiquitination and degradation.  Ubiquitination of CHEK1 is required to insure that activated CHEK1 does not accumulate as cells progress through S phase, or when replication forks encounter transient impediments during normal DNA replication (By similarity).  Involved in endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation.  Able to recognize and bind denatured glycoproteins, which are modified with not only high-mannose but also complex-type oligosaccharides.  Also recognizes sulfated glycans.
What are the official names of this protein?
F-box only protein 6, F-box only protein 6b, F-box protein that recognizes sugar chains 2, F-box/G-domain protein 2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TENA_CHICK
Sequence: MGLPSQVLACAILGLLYQHASGGLIKRIIRQKRETGLNVTLPEDNQPVVFNHVYNIKLPVGSLCSVDLDTASGDADLKAEIEPVKNYEEHTVNEGNQIVFTHRINIPRRACGCAAAPDIKDLLSRLEELEGLVSSLREQCASGAGCCPNSQTAEGRLDTAPYCSGHGNYSTEICGCVCEPGWKGPNCSEPACPRNCLNRGLCVRGKCICEEGFTGEDCSQAACPSDCNDQGKCVDGVCVCFEGYTGPDCGEELCPHGCGIHGRCVGGRCVCHEGFTGEDCNEPLCPNNCHNRGRCVDNECVCDEGYTGEDCGELICPNDCFDRGRCINGTCFCEEGYTGEDCGELTCPNNCNGNGRCENGLCVCHEGFVGDDCSQKRCPKDCNNRGHCVDGRCVCHEGYLGEDCGELRCPNDCHNRGRCINGQCVCDEGFIGEDCGELRCPNDCHNRGRCVNGQCECHEGFIGEDCGELRCPNDCNSHGRCVNGQCVCDEGYTGEDCGELRCPNDCHNRGRCVEGRCVCDNGFMGEDCGELSCPNDCHQHGRCVDGRCVCHEGFTGEDCRERSCPNDCNNVGRCVEGRCVCEEGYMGIDCSDVSPPTELTVTNVTDKTVNLEWKHENLVNEYLVTYVPTSSGGLDLQFTVPGNQTSATIHELEPGVEYFIRVFAILKNKKSIPVSARVATYLPAPEGLKFKSVRETSVQVEWDPLSISFDGWELVFRNMQKKDDNGDITSSLKRPETSYMQPGLAPGQQYNVSLHIVKNNTRGPGLSRVITTKLDAPSQIEAKDVTDTTALITWSKPLAEIEGIELTYGPKDVPGDRTTIDLSEDENQYSIGNLRPHTEYEVTLISRRGDMESDPAKEVFVTDLDAPRNLKRVSQTDNSITLEWKNSHANIDNYRIKFAPISGGDHTELTVPKGNQATTRATLTGLRPGTEYGIGVTAVRQDRESAPATINAGTDLDNPKDLEVSDPTETTLSLRWRRPVAKFDRYRLTYVSPSGKKNEMEIPVDSTSFILRGLDAGTEYTISLVAEKGRHKSKPTTIKGSTEEEPELGNLSVSETGWDGFQLTWTAADGAYENFVIQVQQSDNPEETWNITVPGGQHSVNVTGLKANTPYNVTLYGVIRGYRTKPLYVETTTGAHPEVGELTVSDITPESFNLSWTTTNGDFDAFTIEIIDSNRLLEPMEFNISGNSRTAHISGLSPSTDFIVYLYGISHGFRTQAISAAATTEAEPEVDNLLVSDATPDGFRLSWTADDGVFDSFVLKIRDTKRKSDPLELIVPGHERTHDITGLKEGTEYEIELYGVSSGRRSQPINSVATTVVGSPKGISFSDITENSATVSWTPPRSRVDSYRVSYVPITGGTPNVVTVDGSKTRTKLVKLVPGVDYNVNIISVKGFEESEPISGILKTALDSPSGLVVMNITDSEALATWQPAIAAVDNYIVSYSSEDEPEVTQMVSGNTVEYDLNGLRPATEYTLRVHAVKDAQKSETLSTQFTTGLDAPKDLSATEVQSETAVITWRPPRAPVTDYLLTYESIDGRVKEVILDPETTSYTLTELSPSTQYTVKLQALSRSMRSKMIQTVFTTTGLLYPYPKDCSQALLNGEVTSGLYTIYLNGDRTQPLQVFCDMAEDGGGWIVFLRRQNGKEDFYRNWKNYVAGFGDPKDEFWIGLENLHKISSQGQYELRVDLRDRGETAYAVYDKFSVGDAKTRYRLRVDGYSGTAGDSMTYHNGRSFSTFDKDNDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSSFRNLEGRRKRA
What is the function of this protein?
Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration.  Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
What are the official names of this protein?
Tenascin, TN, Cytotactin, GMEM, GP 150-225, Glioma-associated-extracellular matrix antigen, Hexabrachion, JI, Myotendinous antigen, Neuronectin, Tenascin-C, TN-C.
What is the protein family that this protein belongs to?
Belongs to the tenascin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: COAD_BORPA
Sequence: MIIAVYPGTFDPLTRGHEDLVRRAATLFDKVVVGIAHSRNKKPFFTIEERVDIAREVLGHYPNVEVHSFGGLLKDFVRDQNGRVIIRGLRAVSDFEYEFQMAGMNRHLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVERWLQAKAKERREQSAQGGA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCA1B_ASPOR
Sequence: MYHPNYNYPPPQPGWGGGYYPPPQQHQQQQQWSPPPPQPYYSNGYPPPSQSPHSYSPPQYPPHGQYEYGHHTPTPPPSSGSQYRSYHSHSPSWGQMPPRPPMEAQQFGKGAPSNYRFQYSACTGRRKALLIGINYAGQPNALRGCINDVTNMSTFLHERYGYRREDMVILTDDQQNPMSVPTKANILRAMQWLVKDAQRNDSLFIHFSGHGGRTPDLDGDEEDGYDDVIYPVDYRTAGHIVDDDMHAIMVRPLQPGVRLTAIFDSCHSGTALDLPYVYSTQGILKEPNLAKEAAQDLFSAITSYGQGDFASVAQTAIGFLKKAALGESARERTVKTKTSPADVVMFSGSKDTQTSADTFQDGQARGALSWAFIKTLQARPNQSYLQLLNSIRSELEGKYSQKPQLSCSHPLDTNLLFVM
What is the function of this protein?
Involved in cell death (apoptosis).
What are the official names of this protein?
Metacaspase-1B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: RLMH_TRIL1
Sequence: MKLRIIWLGKTRDPWIKQGVTEYSGRIERYLPLAIDELKDEKDATLEEGRRREGERLLKQLSPNAVLVALDERGQQLDSVKFAEFIGKHRDSGTTELVFAIGGSYGFSDEVRSRAGKVLALSAMTFTHQMVRPFLLEQIYRACTILNNEPYHH
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM13_CANGA
Sequence: MALFGGSSSQAPASATDNKVQAFKQQIAQEIAVANATDLVNKVSENCFEKCLQSPYKDGNEGCVDQCLAKYMRSWNVISKTYINRIQDASTTGEI
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.  The TIM8-TIM13 complex is non essential and only mediates the import of few proteins, while the predominant TIM9-TIM10 70 kDa complex is crucial and mediates the import of much more proteins (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM13.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: HAPR1_MOUSE
Sequence: MEERKEEGEAEIQEHGPEHWFSKWERQCLAEAEQDEQLSPELQEEAAAAAQPEHKQQKLWHLFQNSATAVAQLYKDRVCQQPGLSLWVPFQNAATAVTNLYKESVDTHQRSFDIGIQIGYQRRNKDVLAWVKKRRRTIRREDLISFLCGKVPPPRNSRAPPRLTVVSPNRATSTETSSSVETDLQPFREAIALHGLSGAMASISVRSSTPGSPTHVSSGPNASRRRNGLHDVDLNTFITEEMALHLDNGGTRKRTSAQCGDVITDSPTHKRNRML
What is the function of this protein?
Acts as a central player within a network of stress response pathways promoting cellular adaptability.  The E3 ligase HUWE1 assists HAPSTR1 in controlling stress signaling and in turn, HUWE1 feeds back to promote the degradation of HAPSTR1.  HAPSTR1 represents a central coordination mechanism for stress response programs.  Functions as a negative regulator of TP53/P53 in the cellular response to telomere erosion and probably also DNA damage.  May attenuate p53/TP53 activation through the E3 ubiquitin ligase HUWE1.
What are the official names of this protein?
HUWE1-associated protein modifying stress responses.
What is the protein family that this protein belongs to?
Belongs to the HAPSTR1 family.
Protein: THIC_PARMW
Sequence: MIEQAVADLWLPIAVLIMRASWVSPRKGQANVSQMHYARQGVVTEEMAYVAKRENLPESLVMEEVARGRMIIPANINHTGLEPMAIGIASKCKVNANIGASPNASDAAEEVNKLKLAVKYGADTVMDLSTGGVNLDEVRTAIIDASPVPIGTVPVYQALESVHGSIEKLDEDDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHRQNPLYTRFDDICEIFKRYDCTFSLGDSLRPGCQHDASDAAQLAELKTLGELTRRAWKHDVQVMVEGPGHVPLDQIEFNVKKQMEECNEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWHGTAMLCYVTPKEHLGLPNAEDVREGLIAYKIAAHAADIARHRPGARDRDDELSRARYNFDWNKQFELSLDPERAKEYHDETLPADIYKQAEFCSMCGPKHCPMQTKITEEDIEGLEKVLEARGAAELTPVKLDKAD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: RS19_STAA8
Sequence: MARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNFIGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHVADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: HIS3_MYCBT
Sequence: MTLDPKIAARLKRNADGLVTAVVQERGSGDVLMVAWMNDEALARTLQTREATYYSRSRAEQWVKGATSGHTQHVHSVRLDCDGDAVLLTVDQVGGACHTGDHSCFDAAVLLEPDD
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAST_MOUSE
Sequence: METAVYAKSTRNEKVLNCLCQKPDALFKLICFPWAGGGSTHFAKWGRKINGLLEVHAVRLAGRETRFEEPFSNDIYQIAEEVVTALLPIIRDKAFAFFGHSFGSYIAFITALHLKEKYKMEPLHIFVSSASAPHSEFRPQVPDINKLSEEQIRDHLLIFGGTPKHLIEDQDFLKQCIPLLKADVDIVKKFIFDKPSKALLSRDITCFIGSEDVVKDIEGWKDITSGKFDVLKLPGDHFYLMEPNNEDFIKNYIVKCLELSSLDYF
What is the function of this protein?
Contributes to the release of free fatty acids from fatty acid synthase (FASN).  Has broad substrate specificity, giving rise to a range of free fatty acids with chain lengths between 10 and 16 carbon atoms (C10 - C16).
What are the official names of this protein?
S-acyl fatty acid synthase thioesterase, medium chain, Oleoyl-ACP hydrolase, Thioesterase II, Thioesterase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the thioesterase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TPIS_CAMHC
Sequence: MIVAANLKCNHTRASFLNFTKKLDNFLSGEASNFKKNEILIFPPNTAFCDQISNFTQGAQNFFPCENGSFTGEIGADMLNEFGIKSVLIGHSERRVIFSESDRMVLEKFKFAKKRGWRIIFCVGESDIVRMNGNYREVLSDQLSEIDLDYENLIIAYEPIWAIGTGKSAKNEQIEEVLEFLAEKTEAPLLYGGSVNLKNISQISKLPHCSGVLIGSASWEAENFINLLKELQ
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4HA3_RAT
Sequence: MGPGARLAALLVLLKLGVGDPAAAAGREDTFSALTSVARALAPERRLLGTLRRYLRGEEARLRDLTRFYDKVLSLHEDLKIPVVNPLLVFTLIKRLPSDWRNVVHSLEATENIRAPKDGYEKVEQDLPAFEDLEGAARALMRLQDAYMLNVKGLAQGVFQRVTGSSITDLYSPRQLFSLTADDCFQVGKVAYDTGDYYHAIPWLEEAVSLFRRSYGEWKTEDEASLEDALDYLAFACYQVGNVSCALSLSREFLVYSPDNKRMARNVLKYERLLAENGHLMAAETAIQRPNVPHLQTRDTYEGLCQTLGSQPTHYQIPSLYCSYETNSSPYLLLQPARKEVIHLRPLVALYHDFVSDEEAQKIRELAEPWLQRSVVASGEKQLQVEYRISKSAWLKDTVDPVLVTLDRRIAALTGLDIQPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYKMKSGNRAATLMIYLSSVEAGGATAFIYGNFSVPVVKNAALFWWNLHRSGEGDDDTLHAGCPVLVGDKWVANKWIHEYGQEFRRPCDTNPED
What is the function of this protein?
Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
What are the official names of this protein?
Prolyl 4-hydroxylase subunit alpha-3, 4-PH alpha-3, Procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-3.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RL28_BRADU
Sequence: MSRRCELTAKGPLVGHKVSHSNIKTKRRFLPNLVNVTFISEALERNVRLRVSTNAVKSVDHNGGLDAFLLKASADALSPRALELKRAIQKKVGVTAPVKKAS
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MURA_ECO7I
Sequence: MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y296_RICPR
Sequence: MKRINKVLLSLLCLVIAYAGYSQIIPTYSVDSVTIQNLLPNVDEDTLVLINIDNTIITPKSKLFRYQDNAYINFTKYLYSLAANNASVNKTIAKLIVQRQMMLVESQWVDLINKMKNQGATVLGLQEITAPCNLIENYERWLYTILYGLNINFTRKVNDKEVFRFNPSDAEAPIFYLGIIFTGNINKVNTLIEFLKIIPIPPKKIVIFANNKKDLENMDSYLSMVDIGYYGIEYFGWQMLPGSPDNQIAELQQSTFLNTGQWLEDDTAAKMLNK
What are the official names of this protein?
Uncharacterized protein RP296.
Protein: PCKG_THESM
Sequence: MTPEDYLKKRLDPEQFEKIKGIDNPELNEFLAKYIELLNPARVFICTDSKEDENYIRRRAIEYGEEKSLAMEGHTIHYDGYYDQARDKARTKILVPKGVEIPFINTMDREKGLKEIHEIMKDIAKGKELFVCFFVLGPKNSVFTIPAVQLTDSAYVAHSEFILYRKGYEEFKRLGREAKFLKFVHSAGELDERKTSKNIDKRRVYIDLEGETVYSANTQYGGNTIGLKKLAFRLTIKRAVEEGWLSEHMFLMRINGPNGRKTYFTGAYPSMCGKTSTAMISWENIVGDDLTFIVDMKGEARGANVEKGVFGIIQGVNQEDDPIIWEVLHSPNEIIFSNVLVKDGKPYWNEMGIPIPDEGENHSGKWWRGKKDSEGNEISPSHKNARFTVSLDAFPNTDLEALETPCGVRVGGMIFGGRDADTWPPVREAFDWAHGVITMGAALESETTAATLGKEGVRAFNPMAILDFLSVHIGKYLKNYLEFEKKLRIKPKIFAVNYFLREKDGKWLNHKLDKSVWLKWMELRVHGDVDAIKTPVGYIPKYEDLKRLFKEVLNKDYSREDYEKQFVIRVPEFLAKIERIEKIYRDVGNIPEELFKVLEEERHRLIEAKEKYGDYISPFKFL
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP51_BACLI
Sequence: MERQVFIRLRHRLEADP
What are the official names of this protein?
Stage V sporulation protein AA.
Protein: PGK_SHELP
Sequence: MAIINMSALDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIKLALEKGAAVMVMSHLGRPTEGEYNSEFSMQPVVDYLEKALDCPVRLAKDYLDGVEANVGEVVVFENVRFNVGEKKNDEALAKKLAALCDVYVMDAFGTAHRAQASTHGVGLYAPVACAGPLLAGELEALGKAMDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLIDEAKRLVANAQSRGGDIPVPTDVVVASEFSPTASATLKAVDQVADEDMIFDIGPDSAEALAEILKNAGTIVWNGPVGVFEFDQFGEGTKRIAQAIADSSAFSIAGGGDTLAAVDKYDIADKVSYISTGGGAFLEFLEGKELPAVAMLESRGE
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_SALPA
Sequence: MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEGFIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIAVVSTSKGVMTDRAARQAGLGGEIICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ATG18_KLULA
Sequence: MSNLPIINFINFNQNGSCISMGTSQGFKIFNCEPFGRFYQDEEGGCGIVEMLFSTSLLAVVGMGDNPAMSPRRLRMLNTKRHSVICEVTFPTTILSVKMNKSRLAVLLQEQIYIYDISNMRLLHTIETSMNAQGIMSMSPNSENNYLVYPSPPKVINSEIKDHATTNNINIKKTDAVDDTIKKDYSLQVPSDITGQQQQQQPGVDPATSNNTANKIIKNGDVIVFNLQTLQPTMVIEAHKGEIAALKLSADGTLLATASEKGTIIRVFNVENGSKVYQFRRGTYPTKISSLSFSKDNQFLAVCSSSKTVHIFKLGKNTVDNKSNELNSDDEIEDDLVPRYGDEDEEDEEIDEEATSINSNHSSKEPVVDAKRSTVGRMIRKSSQRLSRKAARTLGAYFPIKVSSILEPSRHFASLKITTSSNQPIKAIAAIDDPIELSIKEYPDLFEKNASNNGDYQNSDTLTMVPIRVVSSEGFMYKYISDPERGGDCILLEQYSLLSD
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Necessary for proper vacuole morphology.  Plays an important role in osmotically-induced vacuole fragmentation.  Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy.  Involved in correct ATG9 trafficking to the pre-autophagosomal structure.  Might also be involved in premeiotic DNA replication (By similarity).
What are the official names of this protein?
Autophagy-related protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: RS18_STRPC
Sequence: MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: OBG_ALBFT
Sequence: MKFVDEAYIDVSAGDGGAGCVSFRHEKYKEFGGPNGGDGGRGGHVFAVADPNLNTLVDFRFSRRHDAKRGEHGMGSDMFGAAGDDITLKMPVGTIISDAETGEVLFELLTPGEVITIAKGGDGGFGNLRFKSAINRAPRQKTPGWPGEKRNLKLELKVLADVGLLGMPNAGKSTLISAISNARPRIADYPFTTLHPNLGVVRVGPEQSFVVADLPGLIEGASEGAGLGHLFLRHLQRTRLLLHVVDMAPFDEGVDTVAQAKAIVNELKKYDPALYNKPRWLVLNKLDMVPLEHREALVKDFVKRFKFKGPVFQISALTREGCESLIKIIYQHVKAQQKAEQTPEAVDQRFAPDTE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGP22_ARATH
Sequence: MASLKFPLEILAVFVIISVILLPIAQSHSSSPAPAPTSDGTSIDQGIAYVLMMVALALTYFIH
What is the function of this protein?
Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death.
What are the official names of this protein?
Arabinogalactan protein 22, AtAGP22, Arabinogalactan peptide 22, AG-peptide 22.
What is the protein family that this protein belongs to?
Belongs to the AG-peptide AGP family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: PB2_INBLE
Sequence: MTLAKIELLKQLLRDNEAKTVLRQTTVDQYNIIRKFNTSRIEKNPSLRMKWAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVTWWNTYGPIGDTEGFEKVYESFFLRKMRLDNATWGRITFGPVERVRKRVLLNPLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTMITPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPGGNKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSCLAALDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIGNGTIQKIGIWDGEEEFHVRCGECRGILKKSQMRMEKLLINSAKKEDMKDLIILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQWGYEESPKASELHGINELMNASDYTLKGVVVTKNVIDDFSSTETEKVSITKNLSLIKRTGEVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKNLVTLKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQEVMKTDQFIKLLPFCFSPPKLRSNGEPYQFLRLMLKGGGENFIEVRKGSPLFSYNPQTEILTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGDFKTIEELERLKPGEKANILLYQGKPVKVVKRKRYSALSNDISQGIKRQRMTVESMGWALS
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds a wide range of cap structures of target pre-RNAs which are subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.