PharMolix/UniProtQA huggingface dataset:
Protein: AK1H_ECOLI
Sequence: MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAVTERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKALLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRYAAEKSRRKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARKLLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEGKVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
What are the official names of this protein?
Bifunctional aspartokinase/homoserine dehydrogenase 1, Aspartokinase I/homoserine dehydrogenase I, AKI-HDI.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the homoserine dehydrogenase family.
Protein: Y1356_STRP8
Sequence: MKTIAFDSNKYLNLQRDHILERISQFDGKLYMEFGGKMLEDYHAARVLPGYEPDNKIKLLKELKEQVEIVIAINANNIEHSKARGDLGISYDQEVFRLIDKFNTLDIYVGSVVITQYNNQPAADAFRKQLEKNGIASYLHYPIKGYPTDINHIISSEGMGKNDYIKTSRNLIVVTAPGPGSGKLATCMSQMYHDQINGVKSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTESAVKKIELLMNDIGVTPDDRHVTVAAHQKAEQTGQPALALQLPNGQIVTGKTSELFGPTAAVIINAIKTLAKIDKTTHLIEPEYVKPIQGLKVNHLGSHNPRLHSNEILIALAITAMTSEEANLAMKELGNLKGSEAHSTVILTEEDKNVLRKLGVNITFDPVYQHHKLYRK
What are the official names of this protein?
UPF0371 protein spyM18_1356.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: HEN1_MOUSE
Sequence: MMLNSDTMELDLPPTHSETESGFSDCGGGPGPDGAGSGDPGVVQVRSSELGESGRKDLQHLSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLAICYISYLNHVLDV
What is the function of this protein?
May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.
What are the official names of this protein?
Helix-loop-helix protein 1, HEN-1, Nescient helix loop helix 1, NSCL-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTSH_RICTY
Sequence: MNNQGRSILAWAALFIFVILLFNVFQSDGLLGVRNNITFSDFLTRVDERTINSVKIQGRVIEGTSNDGSTFSTYSPDYPDLVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGVWVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGIDEAKEELTEIVDFLRDPSKFQKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMFEQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAATNRPDVLDRALLRPGRFDRQIAVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFSGAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVVRRSIAMSEKEKRLTAYHEGGHALVGLYCPAASPIHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEEIIFGKNKVTSGAASDIKGATNIARAMVTKAGLSDLIGPIFHGSSSDDMYGRQQSNEISEATAKLIDAEVKKIITQGYEFAKDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDSEEENKFPFNDAHTIKIDKEKLHEKTKTTKAQKENIAS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: TTCA_SALNS
Sequence: MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEQLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIVRFAEAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVDGGDLAFDREEIPLQPAGWQPEEDDTALEALRLDVIEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPPA_CALMQ
Sequence: MRIIPRTMCTQHPDYANVPQWVVNDFIKGDDEVYEAYMNYSIYDCQETMWDFEGKDVDIYVVRKLLENYGGFFINKVLGEDIYLTYRLPNPNVEASDRKIFAEALETIPMAYDLARVFYGKPVKAIFEVIFPLTSSSRDLIMTLRYYERIVAGKCSVELDDGLKVSDVIGEVEPKTIEVIPLVEDMESLVRIDSIIEGYVKVAKPQYLRVFIARSDPAMNYGLIPAVLLAKIALSRVYAIGNSLGLSIYPIIGVGPTPFRGNFNPRNVNNTLKEYPGVYTFTVQSAFRYDYPVDNAKDAINLINNSKPTEPVILSSDEEELALTIIRQYTDRYQAEVEGLANAVNYIAQLLPPRRTRRLHIGLFGYGRGFRGVTLPRAIAFVGALYSIGIPPEILGLSTLLKLNERQWGVLEGNYVNLWSDLSDAAQYICMECIEQLPSMKSELRVSKETIAMVLEDIKAIDELGVKVSSPGFEQRKHALLTKLFLESVNNSYINDAKAYLLDMAKVRRAIG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: YOHJ_SALA4
Sequence: MSKSLNIIWQYIRAFVLIYACLYAGIFLASLLPITIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFVVVSWSSHLIHGERKVVGQKGTKK
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL29_PSEE4
Sequence: MMKANELREKSAQQLNEQLLGLLRDQFNLRMQKATGQLGQSHLLSQVKRDIARVKTVLNQQAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: TRAA_ECOLX
Sequence: MNIEAYPHDFRGSLAVVSATGVAGCRTWTLRSVETGKHYELAPASIEGWPLPAKREDSRPNSIIVNYDGNDVIALELATGELYRTRAPATTLRLRR
What are the official names of this protein?
Protein TraA.
Protein: NS1_FPV
Sequence: IQTKKEVSIKCTLRDLVSKRVTSPEDWMMLQPDSYIEMMAQPGGENLLKNTLEICTLTLARTKTAFELILEKANNTKLTNFDLANSRTCQIFRMHGWNWIKVCHAIACVLNRQGGKRNTVLFHGPASTGKSIIAQAIAQAVGNVGCYNAANVNFPFNDCTNKNLIWIEEAGNFGQQVNQFKAICSGQTIRIDQKGKGSKQIEPTPVIMTTNENITIVRIGCEERPEHTQPIRDRMLNIKLVCKLPGDFGLVDKEEWPLICAWLVKHGYESTMANYTHHWGKVPEWDENWAEPKIQEGVNSPGCKDLETQAASNPQSQDHVLTPLTPDVVDLALEPWSTPDTPIAETANQQSNQLGVTHKDVQASPTWSEIEADLRAIFTSEQLEEDFRDDLD
What is the function of this protein?
Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication.  Also plays a role in viral packaging and transactivation of several promoters.  Binds site-specifically to 2-3 approximate tandem copies within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR).  Cooperatively binds Ori with host PIF and probably other host factors, which activate the nickase function of NS1.  Becomes covalently attached to the 5' end of the nick and provides a 3'OH for priming DNA synthesis.  The helicase activity unwinds DNA in a 3'-5' direction on the longer strand.  Inhibits the host cell cycle during the G1/S transition, the S-phase, and the G2/M transition.  These arrests may provide essential cellular factors for viral DNA replication.  Promotes apoptosis in host cell.
What are the official names of this protein?
Initiator protein NS1, NS1, NCVP1, Non-capsid protein NS-1, Non-structural protein 1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: EFG_ENTFA
Sequence: MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKGYRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYKVPRIVFCNKMDKIGADFFYSVESLHDRLQANAHPIQIPIGAEEDFTGIIDLIKMKAEIYTNDLGTDIQETDIPEDYLEKAQEWREKLVEAVAETDEDLMMKYLEGEEITEEELVAGIRQATINVEFFPVLAGSAFKNKGVQLMLDAVLDYLPSPLDIDAIKGIDTKTDEETTRPADDEAPFASLAFKVMTDPFVGRLTFFRVYSGVLESGSYVLNASKGKKERIGRILQMHANTRQEIDKVYSGDIAAAVGLKDTTTGDTLCALDAPVILESIEFPDPVIQVAVEPKSKADQDKMGVALQKLAEEDPSFRVETNVETGETVISGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRAATKAEGKFVRQSGGKGQYGHVWVEFTPNEEGKGFEFENAIVGGVVPREYIPAVEKGLEDSMNNGVLAGYPLVDIKAKLYDGSYHDVDSNETAFRVAASMALKAAAKNANPVILEPMMKVTITVPEDYLGDIMGHVTSRRGRVEGMEAHGNSQIVNAMVPLAEMFGYATTLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNGGNA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_COLP3
Sequence: MVKALDRSLALLKQEKIAVLYGGNSAEREVSLNSGQAIAKGLEDAGFNVVLIDTKVVPLTDLVSNKIDRVFIALHGRGGEDGCLQGALEYLDIPYTGSNVLGSSLSMDKVRSKQIFKACGIPTAPFTVVNKAEFSTLSLENILADLGGRVMVKPANEGSSIGMAQAKTIAQLRNALIEAFGFDTQVLLEAWIDGPEYTVTILGDKALPAIHMETPREFYDYEAKYQSTSTQYHCPCGLNERDENEIKSLSMKAFNATGAQGWGRVDIMRNKTGEWQILEVNTVPGMTETSLVPKAAKVFGLNFSELVTQILQLSVKE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_NATTJ
Sequence: MRIILMGPPGAGKGTQAEKLSKELDVPHIATGDIFRKAVSEGTELGKEAKSYMDAGQLVPDDVVIGIVEERLKKPDCHEGFILDGFPRTVTQAEALDKVLSDNPLTAAVYIDVSKDELIDRLSGRRICRKCGKSYHIKFNPPQVRGVCDEDEGELYQRDDDNEETAKERLEVYLENTQPLVEYYQDRGILKKIDGTKSPEEVFRDILKAVQAKQ
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_BRUSI
Sequence: MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPILRPDVLIVARGGGSLEDLWGFNDEIVVRAVAASHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVSPGDALSVRFRDGDVGVVARAGLTIPDPTKGQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_LATSS
Sequence: MASEHIEHKLALLPALPGCYLMKDINAQIIYVGKAKNLKNRVRSYFKSSHEGKTAKLVSEIVDFETIITSTNKEAFLLEITLIQKHQPYFNIKLKRGTGYPYIKITNERDPRLLITGDVKKDGSYYFGPYPDVYAAQETLRFLQRVYPLRRCQGHQGRPCLYYHMGQCLGACFQEVPEAAYTEQIKKIKRFLNGQVDNVKKDLTEKMATAAQEMQFERAAELRDQLRYIEATVEKQKIISNDHTPRDLFAFYMDKGWLSIQIFFIRQARLIRREKRLFPCVNTPEEELATFILQWYNRKNNVLPREILVPDGIEKQVLSDILQVPIRTPQRGEKKALMEMAQKNSRLVLEEKFRLLELDNRKTVGAQDEIMDALGLPHGHVIEAFDHSHIQGTDPVSAMVTFVDGRAEKKLYRKYKLTQTAERAGANEDANTREVIYRRYSRLLKEGKALPDLILMDGGVVELNAAKDVLENELGLTIPVAGMVKDNHHKTASLLFGEADQTIQLDPKSQGFYLLTRIQDEVHRFAISFHRQLRGKNSLSSKLDDIKGVGPKTRTKLLKNFGSMKHIKDASVEELEALGISKTVAQTIKLSL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_ENTFA
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQKTVKLVDAAYDYMKNVAEEGGVALFVGTKKQAQEAIKDEAIRAGQYYVNHRWLGGTLTNWDTIQKRIARLKKINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDVMYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITAKMADAFIEGNQGEDQATEELFVEETPEATSIEEIVDVVEGNNESAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: YFW6_SCHPO
Sequence: MGIASSLRLFGKAPASYLFNGFRRQMKNPLMKKGVVYAGVSGTCAAAGYMFGNFVMEKHIYQVKYTEEQEKEVLEVENRLQNLKIVKDLRQNPSFRELRMPFNRSNHSLTNNLLSGPGRITVPPVIFYDKSTRQVYAIAHVGKDVGLDDDTIHPGLIATCMDEVLAICSFLSLPNKIAVTANLKLSNPTKAYTNHFYILRSHLEWTKGRKAQTHGTAYMLDNEDPSKSTCVAIADGLFVEPRFAKYLKHVIPVSLP
What are the official names of this protein?
UPF0644 protein PB2B4.06.
What is the protein family that this protein belongs to?
Belongs to the UPF0644 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: GMCH_MALS4
Sequence: MKGIVSWAVVSAALVLSATESLAFANVSSFEKRTTTGNGWDLDGKSYDYVIVGGGTAGLVLANRLSANQGTTVAVIEAGNSGYDDNDKFVVPDANLYNSAVNTQYDWQFHTSSQKHMNNRRASWPRGKVLGGSSAVNGLYYVRPSETEVNVWSKLAGGSGRWSWNSLLSGMKKSEHFRGPVKSVQNQLQIQYNAGSHGSNGPIGTTWPAVTYDPVERFIKTADSMSGAINNDPYNGNNHGTYVALSSIDKTNWQRSFSRNGYLDPISKRSNLHVLTGHTVTGIIFDRSGKNAQATGVHYAASSNEASHTVHANKEVIISGGAINSPQILQLSGIGDKNLLNGLGIDVVVDLPGVGENLQDHVSAGMSFKPKNKKDAGPTSVTGDAKADSYVNSAVSYTSLGKLFNNKDSILGKIQARAKQIADSHNVSPAVKQGQSKAYNALADTIFPSKVSPVEILGNVMFGSISIQAALQHPLSRGSIKITSKDPFAYPKINPNYFAENLDLVLLREGFKLIREMSQQSPLKDVIDFETVPGDKVQTNEDWENWIRSAAGTEYHPSSTCAMLPRGDGGVVDENLKVYGTSNLRVVDASVTPIAMSCHLESVVYGLAEVAADIILGN
What are the official names of this protein?
GMC oxidoreductase family protein Mala s 12.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYAY_BURCH
Sequence: MSDTEYLARAEAVLAAVERTVDVANDGDHDIDLERNGSVLTLTFENGSKIIVNLQPPMKEVWIAAKAGGFHYRFIDGEWRDTRTGTEFFSALTEYATQQAGLPITFSA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: NHAA_BRUSU
Sequence: MNHSPQSARPVSIMRRFLDSEAAGGITLMAAAALALIVANSPFAQTYFDALHLYIGPLSLAHWINDALMAIFFLLVGLEIKREMLDGQLASWPNRMLPGIAAAGGVILPAIIFAVLNHDNPAKLRGWAVPSATDIAFALGVLSLLGSRAPSSLKVFLATLAILDDLAAVVIIAIFYTAEISMPYLGAAFITAAVLFVMNRMGVVKLLPYLISAVILWFFVFNSGVHATVAGVVAALMIPLKPAPGRPDDMTSPLHKLEHALAKPVAFIVVPIFGFANAGISFKGLEASVLGDTLTLGILLGLFLGKQFGVFGAAWLAIKTGLAEKPMGASWVQLYGVAILCGIGFTMSIFIGLLSFPSDLMQTETKIGVLSGSALSAICGYLLLRAAARPKRG
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AMPA_RHOPA
Sequence: MPDAVKVGFVLFATPARGTLIVFCDDGLKFGATATKALGAAVATVKRAAATAQFKGKSGSALDLLAPEGLKVGRLIVVGAGKAASINDYDLLKLGGAVAGKIGAGDTAVTVVADLPTGAMKPEQAAAIASGIRLRAYKFDRYKTKKKDDENGAANASVTLAVADPAAAKKAFTPDSHVVDGVILARELVNEPPNVLYPEEFAKRAAQLKKLGVEVQILDVKAMTQLKMGALLGVSQGSAHPGRTVIMRWNGGKKGEQPLAFVGKGVCFDTGGISIKPSASMEDMKGDMGGAACVVGLMHALAARKAKVNAVGAIGLVENMPDGNAQRPGDIVTSMSGQTIEIINTDAEGRLVLADVLWYVAQKHKPKFMVDLATLTGAIMVALGTEYAGLFSNNDQLAERLAAVGQSTGEKVWRMPLGPEYDKQIDSQFADMKNTGSRNGGSITAAQFLQRFVDGTPWAHLDIAGTAMASPKNEINQSWGSGYGVRLLNQLVAEYYEAKK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEX1S_TITSE
Sequence: MKLSCGFLLIFLVLSAMIATFSEVEATVKCGGCNRKCCPGGCRSGKCINGKCQCYGRSDLNEEFENYQ
What is the function of this protein?
Probable weak potassium channel blocker.
What are the official names of this protein?
Peptide TsPep3, Tityustoxin-13, Ts13.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Epsilon-KTx 01 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_STRU0
Sequence: MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: F13A_RAT
Sequence: MSDTPATTFGGRGAIPPNNSNAAGVDLPTEDLQGLVPRGVSLKDYLNVTAVHLFKERWDSNKIVHHTDKFDNNKLIVRRGQTFYIQIDFNRPYDPRKDLFRVEYVIGRYPQENKGTYIPVPVVTELQSGKWGAKVIMNEDRSVRLSVQSSPECIVGKFRMYVAVWTPYGILRTQRDPETDTYILFNPWCEEDAVYLDDEKEREEYVLNDIGGIFHGDFNDIKSRSWSYGQFEDGILDACLFVMDKAEMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNVYAYGIPPSAWTGSVDILLEYRSSETPVRYGQCWVLAGVFNTFLRCLGIPARVITNYSSAHDNDANLQMDIFLEEDGSVSFKLTKDSVWNYHCWNEAWMTRPDLPVGFGGWQAVDSTPQENSDGMYRCGPASVQAVKHGHVCFQFDAPFVLGEVNSDLVYITAKKDGTHVVENVDATHIGKLIVTKEIGGDGMQDITDTYKFQEGQEEERLALETALMYGAKKTLNTEGMVKSSSDVDMNFDVENAVLGKDFRVTITFQNNSSNLYTILAYLSGNITFYTGVSKKEFKTESFEVTLDPLSLEKKEVLIRAGEYMSYLLEQGLLHFFVTARINETRVVLAKQKAIVLTIPKVTIKVRGTAMVGSDMVVTVEFTNPLKETLKNVWLHLEGPGVMRPKRKMFREIRPNATVQWEEVCQPWVSGHRKLNASMTSDSLRHVYGELDLQIRRRPTV
What is the function of this protein?
Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot.  Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
What are the official names of this protein?
Coagulation factor XIII A chain, Coagulation factor XIIIa, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
Protein: RR19_COFAR
Sequence: MTRSLKKNPFVANHLLKKIDKLNTKAEKEIIVTWSRASTIIPTMIGHTIGIHNGKEHLPIYITDRMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYC_ORITB
Sequence: MNLYIYNTLSRKKERFVPLNCKSVKMYVCGPTVYDIPHIGNARSVVVYDLLYRVLSFLYDRQNITYVRNITDIDDKIINRAKELKINIFKLTHETTIKFHEDMSYLGCWNPTIEPKATDNIDVMINIITSLIQTGNAYSTDDGHVYFAVKTFQDYNLLSRRTFDSMMLNSSESSEQQKSYFADFVLWKPANADNEDIDAVFDSPWGKGRPGWHIECSAMSYKFLGENFDIHGGGADLIFPHHTNEIAQSRCAFPKSRHASYWVHNGFLTVKGEKMSKSLNNFVTVRDLQKQNINGAAVRLMFLSTHYRKPLDFNDKSLNDAKNIINYLYDTIDSVNVTVQQQDNTKAEFKGNAFTVEFINALLDDLNSPKAIVCLLNIAKQIRRQNQSEYKLALTQALLYASNLLGILHNYQFIKDSNDVKDNSNVIPHEIDLLIAKRIQAKQDKDWNLADQIRSQLLSNGISLTDKADGTTSWKVIK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPB_PHOPR
Sequence: MNNMSLEMLEKLEAKVQMAVDTISLLQMEIEELKETNESLTAEANELRSNRETLAQDNDKLQNDHQAWQERVRTLLGKMDHVE
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid- cell, in a FtsZ-like pattern.
Protein: CIP4_RAT
Sequence: MDWGTELWDQFEVLERHTQWGLDLLDKYVKFVKERVEVEQSYAKQLRSLVKKYLPKRPAKDDPEIKFSQQQSFVQLLQEVNDFAGQRELVAESLGIRVCLELAKYSQEMKQERKMHFQEGRRAQQQLENGFKQLENSKRKFERDCREAEKAAHTAERLDQDINATKADVEKAKQQAHLRNHMAEESKNEYAAQLQRFNRDQAHFYFSQMPQIFDKLQDMDERRATRLGAGYGLLSEAELQVVPIIGKCLEGMKVAAESVDAKNDSKVLIELHKSGFARPGDLEFEDFSQVMNRVPSDSSLGTPDGRPELRAASSRSRAKRWPFGKKNKTVVTEDFSHLPPEQQRKRLQQQLEERNRELQKEEDQREALKKMKDVYEKTPQMGDPASLEPRIAETLGNIERLKLEVQKYEAWLAEAESRVLSNRGDSLSRHTRPPDPPTTAPPDSSSSSNNSGSQDNKESSEEPPSEEGQDTPIYTEFDEDFEEPASPIGQCVAIYHFEGSSEGTVSMSEGEDLSLMEEDKGDGWTRVRRKQGGEGYVPTSYLRVTLN
What is the function of this protein?
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis.  Also acts as a link between CDC42 signaling and regulation of the actin cytoskeleton.  Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules.  Also enhances actin polymerization in the vicinity of membrane tubules by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex.  Actin polymerization and dynamin may promote the fission of membrane tubules to form endocytic vesicles.  Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells.  Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling.  May be required for the lysosomal retention of FASLG/FASL (By similarity).
What are the official names of this protein?
Cdc42-interacting protein 4, Salt tolerant protein, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP-10.
What is the protein family that this protein belongs to?
Belongs to the FNBP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Golgi apparatus. Cell membrane. Cell projection, phagocytic cup. Note=Localizes to cortical regions coincident with F-actin, to lysosomes and to sites of phagocytosis in macrophages. Also localizes to the Golgi, and this requires AKAP9. Translocates to the plasma membrane in response to insulin stimulation, and this may require active RHOQ (By similarity).