PharMolix/UniProtQA huggingface dataset:
Protein: KAR5_YEAS7
Sequence: MFAMRYVYLFAICIKFVSSSELGKINNLLQGRLIYTDNSVATNVLESKFPFLKSTCVKDALKLFLPQCIANGLESIDAETRVETAIKLSICEFQASGLGEIPENCMVDDLGSMMDCMFELESSSQWWTTYSGNYQRLSSICYENLLPFEKEQILKLFLNITELYDSFGDDVDTKLNHLMFQMEQDSQNFLDDLARMFRNYDNELRNATESNRIILENDLSFFRNKVNDVLYETSEQLEVQIIEKNSQLMNEVDTVHHIMSDLADELAKNDIKSKINDLKDDSLNNLQDLVEMSNDVKEYYSRNNKLVNTELENFSMGLKKQLGGMSKDLSESQMEAIELLQGFNSILHDSLLPSMTDEIVPEMTNFKNTLLQEWTAITSTLNGDFALWNEEIFSTFNDISEKLNGTKKKLDDIEIRVSLVHKNVMTMMRVLDFMWKTSKMIIRCGYLAVKNKYYWLLCSVVWIWSKYRTSRVNVKMIPIKRYYQWAALLLSIYLGAKTGSLIDF
What is the function of this protein?
Required for nuclear membrane fusion during karyogamy.
What are the official names of this protein?
Nuclear fusion protein KAR5, Karyogamy protein 5.
What is the protein family that this protein belongs to?
Belongs to the KAR5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
Protein: CCS1_PARMW
Sequence: MKRLLVWLSDLRVAIVLLLLIALASAVGTAIPQGDPPTSYVDAYAETPWLGLLHGEQVLQLQLDHVYSSGWFLGLLAWLGLALILCSWRRQWPALQAARRWIDYRTPRQLSKLAIAETITCPDAEAGLTQLSAVLQRQGWELKPGLNRLAARKGVIGRVGPLLVHTGMVLLMLGAVWGALAGNRLERFLAPDRTLDLLSPRGDSQLSITLQDFQIERDPAGRPEQFRSLLALSDSETPEEISVNHPLRHRGITIYQADWALAAIGVQIGRSPELQLPLQTYPELGDQVWGLVLPTRPDGSEPVFLSLESEQGPVSVYDSDGSALTLLRPGGPAEEVKGLPLRVASVLPASGLLLKRDPGVPLVYLGFAVLLLGGGLSLVATRQLWAVASDGQLHVGGLCNRNLAAFAQELPLLLQRVVAREQHDSPQSVQSS
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsB.
What is the protein family that this protein belongs to?
Belongs to the Ccs1/CcsB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PTH2_CORGL
Sequence: MTSVSFLSKIQALFAPKPELPAAKWLVVGLGNPGAKYESTRHNVGYMCQDMLIDAHQQQPLTPATGYKALTTQLAPGVLAVRSTTFMNHSGQGVAPIAAALGIPAERIIVIHDELDLPAGKVRLKKGGNENGHNGLKSLTEELGTRDYLRVRIGISRPPAGMAVPDYVLEPVDHDQPGIELAAEAVDLLLAQGLSAAQNAIHSR
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase 2, PTH 2.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDR62_PIG
Sequence: MAALGTGGYVRNDAVEKLPTIMAGVPARRAQSSPPPAPPLCLRRRTRLTAAPEDAVQNRVSLEKVLGITAQNSSGLTCDPGTGHVAYLAGCVVVILNPKENKQQHILNTARKSLSALAFSPDGKYIVTGENGHRPAVRIWDVEEKNQVAEMLGHKYGVACVAFSPNMKHIVSMGYQHDMVLNVWDWKKDIVVASNKVSCRVIALSFSEDSSYFVTVGNRHVRFWFLEVSTEAKVTGTVPLVGRSGILGELHDNVFCGVACGRGQMAGSTFCVSYSGLLCQFNEKRVLEKWINLKVSLSSCLCVSQELIFCGCTDGIVRIFQAHSLHYLANLPKPHYLGVDVAQGLEPSFLFHRKAEAVYPDTVALTFDPNHQWLSCVYKDHSIYIWDVKDINKVGKMWSELFHSSYVWNVEVYPEFEDQRACLPSGSFLTCSSDNTIRFWNLDSNPDSHWQKNIFSDTLLKVVYVESDIQHLQDMSHFPDRGSENGMAVDMKAGVRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVRVEAHDAEVLCLEYSKPETGLTLLASASRDRLIHVLNVEKNYSLEQTLDDHSSSITAVKFTGSRDIQMISCGADKSIYFRSAQQASDGLHFVRTHHVAEKTTLYDMDIDITQKYVAVACQDRNVRVYNTVNGKQKKCYKGSQGDEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECVAKMFGHSEIITGMKFTYDCRHLITVSGDSCVFIWHLGPEITNCMKQHLLEIDQREQPQQNTKDGKWSRDPRQETCTSMPSEISLSPGEQTEDELEEECEPEELLKTPSKESLDSDPRCLLTNGKLPLWAKRLLGDDDVADGSAFHAKRSYQPHGRWAERADQEPLKTILDARDLDCYFTPMKPESLEDSILDTVESQRLAGLLSQSESPQEDGCRHPSLTPPQRESSEVSELLCSLESEVTITGTDSKPCAEEGEGAPGDQQDDFYLRVPSITSKDLNPPEDSGESEADLECSFTAVHSPPRPDPDPPFDVAVPPAPGCPGATEELARPEVPGLSNGSLPQTPEQEKFLRHHFETLTDAPAEELFHGSLRDLKASEAKDDFFNPRLSISAQFLSRFQKPSRFTHTFPTRLPRHPMQSPEVKLTDLAGSQPRAEPLRAGTGYTSPGRTNVLSAGKAEEPLEAWSPLTSCLTGLAPCVSSSSVPPTDKTPPTPTALPTPGLAQGVHTPATSSYVEATAGSRAKMSRSISLEDSKGPVLAELARPPCRPSSLGELSSLGQELRAITTTVTPSSDSEGQEPALPSRGNHEARASLKLTLSSICDRLLLPPPQLEPSAMCVWSQEPVAIQPNVMVTTASFSAPSPVNVSASRLHNSTFLPRFLAPEPLNTSAHPNSPPLPEARPGVPGNITSLLESAPDALSPVHRCPGHCGQPRVPARVPPPGPLELSNVGSIVHRLQTAFQEALDLYHMMVSRDEVSAEQQQAQTELASTFLWIHSQLEANDWLVGTDGAPAQALPSPGPPSPPTLCPLASPDLHALLEHYSELLVQAVRRKAQRD
What is the function of this protein?
Required for cerebral cortical development.  Plays a role in neuronal proliferation and migration (By similarity).  Plays a role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and CEP63 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication (By similarity).
What are the official names of this protein?
WD repeat-containing protein 62.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Shows cell cycle-dependent localization. Accumulates to the spindle pole during mitosis (By similarity). Colocalizes with CDK5RAP2, CEP152 and WDR62 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (By similarity).
Protein: PYRG_SHESH
Sequence: MTTRYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTMMKLDPYINVDPGTMSPTQHGEVFVTEDGAETDLDLGHYERFIRTKMNRRNNFTTGRIYEEVLRKERRGDYLGATIQIIPHITNAIKEKVLAGGEGHDVAIVEIGGTVGDIESLPFLESIRQLSVELGRERSLFMHLTLVPFLGAAGEVKTKPTQHSVKELRSIGIAPDVLVCRGDRPVPANEKAKISLFCNVEERAVISLKDVDSIYKIPALLKAQGLDELVVKRFGITCPEADLHEWEQVIYQEANPTGEVTIGMVGKYIELPDAYKSVNEALKHAGLFNRVSVNIKYIDSQTVEAKGEEVLQGLDGILVPGGFGERGVEGKILAAKYARENNLPYFGICLGLQVALIEFARHVAGLEGAHSTEFNKETPHPVVGLITEWINEEGNVEQRHETSDLGGTMRLGAQLCHLSEGSKAAISYDGNTCVERHRHRYEVNNNYKDRLEKAGLVFSGLSSDRQLVEMIELPNHPWFVAGQFHPEFTSTPRDGQPLFVGFVAAATAYQKRDLG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RS15_MAGSA
Sequence: MSITAERTQELVKEYATKEGDTGSAEVQVAILSERIRNLTEHLKSHKKDFHSRRGLLIMVGQRRRMLDYLKAKDNKRYEGLIGRLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TTC36_MOUSE
Sequence: MGTPNDQAVLQAIFNPDTPFGDVVGLDLEEAEEGDEDGVFPQAQLEHSKALELQGVRAAEAGDLHTALEKFGQAISLLPDRASAYNNRAQARRLQGDVAGALEDLERAVTLSGGRGRAARQSFVQSGLLARFQGRDDDARRDFEKAARLGSPFARRQLVLLNPYAALCNRMLADMMGQLRAPSNGR
What are the official names of this protein?
Tetratricopeptide repeat protein 36, TPR repeat protein 36.
What is the protein family that this protein belongs to?
Belongs to the TTC36 family.
Protein: ATP6_PSEFS
Sequence: MAETTASGYIQHHLQNLTFGQLPNGGWGFAHSAAEAKEMGFWAFHLDTLGWSVALGLIFVLIFRMAAKKATSGQPGALQNFVEVLVEFVDGSVKDSFHGRSPVIAPLALTIFVWVFLMNAVDLIPVDWIPQLAILITGDAHIPFRAVSTTDPNATLGMALSVFALIIFYSIKVKGIGGFIGELTLHPFGSKNIFVQALLIPVNFLLEFVTLIAKPISLALRLFGNMYAGELVFILIAVMFGSGLLWLSGLGVVLQWAWAVFHILIITLQAFIFMMLTIVYLSMAHEENH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NOLC1_RAT
Sequence: MADTGLRRVVPSDLYPLVLGFLRDNQLSEVASKFAKATGATQQDANASSLLDIYSFWLKSTKAPKVKLQSNGPVAKKAKKETSSSDSSEDSSEEEDKAQVPTQKAAAPAKRASLPQHAGKAAAKASESSSSEESSEEEEEEDKKKKPVQQKAVKPQAKAVRPPPKKAESSESESDSSSEDEAPQTQKPKAAATAAKAPTKAQTKAPAKPGPPAKAQPKAANGKAGSSSSSSSSSSSDDSEEEKKAAAPLKKTAPKKQVVAKAPVKVTAAPTQKSSSSEDSSSEEEEEQKKPMKKKAGPYSSVPPPSVSLSKKSVGAQSPKKAAAQTQPADSSADSSEESDSSSEEEKKTPAKTVVSKTPAKPAPVKKKAESSSDSSDSDSSEDEAPAKPVSATKSPLSKPAVTPKPPAAKAVATPKQPAGSGQKPQSRKADSSSSEEESSSSEEEATKKSVTTPKARVTAKAAPSLPAKQAPRAGGDSSSDSESSSSEEEKKTPPKPPAKKKAAGAAVPKPTPVKKAAAESSSSSSSSEDSSEEEKKKPKSKATPKPQAGKANGVPASQNGKAGKESEEEEEDTEQNKKAAGTKPGSGKKRKHNETADEAATPQSKKVKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHEKTKKKRGSYRGGSISVQVNSVKFDSE
What is the function of this protein?
Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification.  Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification.  Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus.  It has intrinsic GTPase and ATPase activities.
What are the official names of this protein?
Nucleolar and coiled-body phosphoprotein 1, 140 kDa nucleolar phosphoprotein, Nopp140, Nucleolar 130 kDa protein, Nucleolar phosphoprotein p130.
What is the protein family that this protein belongs to?
Belongs to the NOLC1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles on curvilinear tracks between nucleolus and cytoplasm. These tracks extend from the dense fibrillar component of the nucleolus across the nucleoplasm to a limited number of nuclear pore complexes.
Protein: IF1_MYCGA
Sequence: MKETNLSIKGVVKEIIKGDKFKVLLENNLLIEAHVSGKIRMHKIRILPGDSVEVEFSPYDLTKGRIIYRH
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFA3A_ARATH
Sequence: MDTSSPSAFVNGALLRRFIGQKVRTVIQVTGSEIGSVVGKSTDDLQIVVRGSSPPSPLTTYLEVIGIAESDNAIRAETWTNFGNTFDTQNYNELCKLANGEFKHLFI
What is the function of this protein?
As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair.  Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (By similarity).
What are the official names of this protein?
Replication protein A 14 kDa subunit A, AtRPA14A, Replication factor A protein 3A, Replication protein A 3A.
What is the protein family that this protein belongs to?
Belongs to the replication factor A protein 3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_ZYMMO
Sequence: MIVALPPLMVAEKPPMALVLGLESSCDETAVALVDNDGNIISSHLATQEILHRPYGGVVPEIAARAHVERLEPLVRKVLNESGKNLSEIDAIAATAGPGLIGGVMVGFVTGKALSLACKKPLIAINHLEGHALTPRLADKTLSFPYLLLLISGGHCQILLVKNVGEYRRLATTIDDAGGEAFDKTAKILGLGFPGGPAVEREALNGDPMAVPLPRPLIKSKEPHFSFAGLKTAVLRAYQSGIYKRHDIAASFQQAVIDCLVNRSEKALKKIEGENIQINAFVIAGGMAANQAIRPALTDLAEAHNLPLIAPPPSLCTDNGAMIAWAGVERFRLGMIDNLESPARARWPLDPHAEKARGAGVKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX113_LYCSI
Sequence: MMKVLVVVALLATLISYSSSEGIDDLEADELLSLMANEQTRKECIPKHHECTSNKHGCCRGNFFKYKCQCTTVVTQDGEQTERCFCGTPPHHKAAELVVGFGKKIFG
What are the official names of this protein?
U1-lycotoxin-Ls1b, Toxin-like structure LSTX-A13.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 04 (U1-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GCH1_STRA1
Sequence: MPNQEKMEKAIYQFLEALGENPDREGLKDTPKRVAKMYIEMFSGLNQDPKEQFTAVFSENHEEVVIVKDIPFYSMCEHHLVPFYGKAHIAYLPNDGRVTGLSKLARAVEVASKRPQLQERLTAQVAQALEDALAPKGIFVMIEAEHMCMTMRGIKKPGSKTITTVARGLYKDDRYERQEILSLIQKG
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RPOB_BUCA5
Sequence: MVYSYTEKKRIRKDFGKRPKVLDIPYLLSIQLNSFKKFIQPDLSGQHGLEAAFRSVFPIRGYNGNSELQYVSYRLGETIFDVKECQIRGATYSAPLRVKLRLVIYERDILEATVKDIKEQEVYMGEIPLMTNNGTFIINGTERVVVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPVSIILRALNYNTEEILNIFFEKNIFKIENNKIVLELVPERLRGETASFNIKKNGIIYVEKGRRITAKHIQELKNNKIKSITVPVEYILGRIVSKNYVDKKTGETIISSNTELSLEILEKLKKLGFYSIETLFTNDLDHGPYISETLRIDSSNDRMSALIEIYRVMRPGEPPTKEATENLFENLFFSEDRYDLSTVGRMKFNRSLLREETKGSSTLNKEDIIDVIKKIIDIRNGKGEVDDIDHLGNRRVRSVGEMAENQFRIGLVRVERAVKERLSIGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGLGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNSYGFLETPYRKVCNGLVSEEIHYLSAIEEGNYIIAQANTNIDKTGFFTDDLVTCRHKGESSLFNRNQVNYMDVSTQQIVSVGASLIPFLEHDDANRALMGANMQRQAVPTLKTDKPLIGTGMERAVAVDSGVTAVAKRSGVVQYVDASRIVIKVDEKEMYSREAGIDIYNLTKYTRSNQNTCINQQPCVNLGEKIKKGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELSCISRDTKLGAEEISSDIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQIFTRDGVKKDKRALEIEDMQLKKIKQDLTEEFKIFESSLFTHIKKTFISLDIETKQLDTLPFEKWFSVDIKQKDKKKEIEKLAKQHHELKEEFNKKIEIKRQKITQGDDLAPGVLKIVKVYLAVKRQIQPGDKMAGRHGNKGVISKINPVEDMPYDENGIPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINHMLKTQEKISNLRKFIQKAFDLGDNLRQKVNLDTFSNEEILRLAKNLKNGIPISTPVFDGAQENEIKQMLKFAGLPTSGQIILFDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELESE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CAS4_FRATN
Sequence: MNMDIFDNDLSIPVNLIRQWCFCPRIVYYQELLAIKPNKPLWVAQGEEFHKKVEQLEKRRSFSRYGLENAIRHFNLSIKSQKYKLHGIVDWVIETDTNVYVVEYKTNPNPNSLGHKLQIAAYALLVQEYFAKPCKTTFLTSDKKSYEIKITDELINKLIKTISDILSTLDSGNKPDSSASDHQCIQCEYYNFCNDR
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  This may be a 5' to 3' ssDNA exonuclease (By similarity).
What are the official names of this protein?
CRISPR-associated exonuclease Cas4.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated exonuclease Cas4 family.
Protein: GAS1_HELAN
Sequence: MAAVGASATPLTNTKSTAEPVRPVANFPPSVWGDLFLSFSLDKSIMEEYAEAMEEPKEQVRRLILDPTMDSNKKLSLIYTVHRLGLTYMFLKEIEAQLDRLFKEFNLEDYVELDLYTISINFQAFRHLGYKLPCDVFNKFKNDDSTTFKESITGDVRGMLGLYESAQLRLKGENILDEASAFAETKLKSLVNTLEGSLAQQVKQSLRRPFHQGMPMVEARLYFSNYQEECSAHDSILKLAKLHFNYLQLQQKEELRIVSQWWKDMRFQETTPYIRDRVPEIYLWILGLYFEPRYSLARIIATKITLFLVVLDDTYDAYATIEEIRLLTDAINRWDISAMNQIPEYIRPFYKILLDEYAELEKQLAKEGRANSVIASKEAFQDIARGYLEEAEWTNSGYVASFPEYMKNGLITSAYNVISKSALVGMGEIVSEDALVWYESHPQILQASELISRLQDDVMTYQFERERGQSATGVDSYIKTYGVSEKVAIDELKKMIENAWKEINEGCLKPREVSMDLLAPILNLARMIDVVYRYDDGFTFPGKTLKEYITLLFVGSSPM
What is the function of this protein?
Sesquiterpene synthase involved in germacrene A biosynthesis (PubMed:19580670).  Germacrene A is a precursor of several sesquiterpene lactones (PubMed:19580670).
What are the official names of this protein?
Germacrene A synthase 1, Terpene synthase 1A, HaTPS1A.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: PRMA_VIBC1
Sequence: MPWIQIKLNATNENAEQIGDMLMEETGALSVTFLDAQDTPVFEPLPGETRLWGDTDILALYDAEADTNFIITQIKASNMLADDFAYKVEQLEDKDWEREWMENFHPMKFGERLWICPSWREIPEPDAVNVMLDPGLAFGTGTHPTTALCLEWLESLDLSGKTVIDFGCGSGILAIAAIKLGAEKVIGIDIDPQALQASRDNAERNGVANQLEVFLPQNQPEGLIADVVVANILAGPLRELAPIIKSLVKPNGDLAMSGVLDTQAEDVANHYRDELHIDPIAEQSEWCRISGRKQG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALU_MYCPN
Sequence: MPKIRKAVIPAAGLGTRLLPATKAIPKEMLPLVNKPTIQYIVEEAVASGIKEILVIVSSKKEAIIDHFDYDFILENALLQKHKDQEHQEIKDIANLAHIYFVRQKHQHGLGDAILHAKSFVGNEDFAVLLGDDVVFGEQPALAQCIQAYEQTDCQVIGVQEVPHDQVNKYGIVTPEANWQKQALVKILGMVEKPAVNEAKSNLAILSRYILKPSIFTALKQVPFGVGGELQLTDGLNYCLQQGEPFFAKHFGGTRFDVGTKNGFIKANLYTALKTDAITKDEVLAILKEFA
What is the function of this protein?
May play a role in stationary phase survival.
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: HIS7_CAUSK
Sequence: MARTAEVVRETKETQIRVWIDLDGTGASTISTGIGFYDHMLESFARHGGFDLKVETKGDLHIDMHHTVEDTGIVLGQAIKEALDGFKGVRRFGHAYIPMDETLTRCAIDLSNRPYLIWKVDFKRPKVGEMDTELFKEFHHAFAMNVGACVHLETLYGDNTHHVAESGFKALARALRQAVEIDPKTGGHAPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARC_RHIME
Sequence: MGQSLLPPSGGDDNIQPVDLKAALEERYLAYALSTIMHRALPDVRDGLKPVHRRIIHAMSEMGLRPNSSFKKCARIVGDVIGKFHPHGDQSVYDALVRLAQDFSQRYPVVDGQGNFGNIDGDNAAAYRYTEAKMTEVAALLLEGIDQDAVDFRPTYNEEDQEPTVLPGAFPNLLANGASGIAVGMATSIPPHNAHELCDAALHLIKHPDATVEDLLFDPANPQRGGIEGPDFPTGGVIVESRASMAESYRTGRGGFRVRARWAVEDLGRGGFQIVVTEIPYQVQKSRLIEKIAELLIARKLPLLEDIRDESAEDVRVVLVPKSRSVDANILMESLFKLTELESRIPLNMNVLSMGRVPRVMALNEVLSEWLAHRREVLQRRSRHRLAAIDRRLEILGGYLIAYLNIDEVIRIIREEDEPKAVMIERFGLTDVQAEAILNMRLRSLRKLEEFEIRTEFDSLSKEKAEIEALLASGDKQWQAVAWEIGEVKKKFAKATELGKRRSTFSDAPDADVEAIQQAMIEKEPITVVISEKGWIRALKGHIADTSSLQFKDGDGLKVSFPAQTTDKILIFTTGGKAYTLGGDKLPGGRGHGEPLRIMVDMENDQDVLTAFVHDPARKLIVSSTAGNGFVVTESDIVANTRKGKQVMNVTMPDEAKLVVPVKGDHLAVVGENRKMLVFPLVQVPEMARGKGVRLQRYKDGGVSDIRSFAIAEGLTWEDSAGRVFTKTRDELIEWMGDRAGAGRVVPKGFPRSGKFSG
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit A, Topoisomerase IV subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HVC2_HETFR
Sequence: ATPSPAILYGLCSCEQTNTDGSLAYGCLAMDYSPEITSITWKKDKEPITTGLKIYPSVLNKKGTYTRSSQLTITESEVGSSKIYCEVRRGESLWIKEILDCKGDIVPPTVILTQSSSEEITSRRFATVLCSIIDFHPESITVSWLKDGQPMDSGFVTSPTCEVNGNFSATSRLTVPAGEWFSNTVYTCQVAHQEVTQSRNITGSQVPCSIGDPVIKLLPPSIEQVLLEATVTLTCVVSNAPYGVNVSWTQEKKPLKSEIAVQPGEDSDSVISTVNISTQAWLSGAEFYCVVSHQDLPTPLRASIHKEEVKDLREPFVSVLLPPAEDVSAQRFLSLTCLVRGFSPREIFIKWTVNDKSVNPGNYKNTEVMAENDNRSFFIYSLLSIAAEEWASGASYSCVVGHEAIPLKIINRTVNKSSGKPSFVNISLALLDTVNSCQ
What are the official names of this protein?
Ig heavy chain C region, Clone 12022.
Protein: ATPG_BURL3
Sequence: MAGMKEIRGKIKSVQNTRKITKAMEMVAASKMRRAQERMRAARPYADKVRAIAAHMSRANPEYRHPFMVANEGAKTAGIILVTTDKGLCGGLNTNVLRATVQKFKELEEKGQKVEATAIGSKGLGFLNRFGAKVLSQVVHLGDTPHLDKLIGAVKTQLDLYSEGKLSAVYIAYTRFVNTMKQEAVIEQLLPLSSEHFEADDGTPATSWDYIYEPDAQAVVDELLVRYVEALVYQAVAENMASEQSARMVAMKAASDNAKTVISELQLVYNKSRQAAITKELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HSLU_PARL1
Sequence: MTSFSPREIVSELDRYIVGQRDAKRAVAIALRNRWRRQQLPDALRDEVLPKNILMIGPTGVGKTEISRRLAKLAEAPFLKVEATKFTEVGYVGRDVEQIIRDLVEIALAMTRERKRKDVQAKAHVAAEGRVLDALVGANASEATRESFRRKLRDGELDEKEIEVEVADSGGGMPTFDIPGMPGSQMGMINLSDIMGKAFGGRTKTRRMAVRDSYDVLVAEESDKLLDQEQLTQEAIRSVENNGIVFLDEIDKICARAERQGGDVSREGVQRDLLPLIEGTTVATKHGAVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELQALSKDDMRRVLTEPEASLIKQYVALLNTENVTLDFTDDGIDAIADIATSVNSTVENIGARRLHTVMERVLDEVSFAATDKAGETVTIDGAYVRKHLGDLSKNTDLSKFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.