PharMolix/UniProtQA huggingface dataset:
Protein: RL32_SHELP
Sequence: MAVQQNKKSRSKRGMRRSHDALSTAQLSVDATSGELHRRHNVTADGYYRGQKVINK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ALND_EMENI
Sequence: MTVQTFYLIGEKERSTRELDVGDPKTVNALRQGLAEVFNILSAEGIDFHDCHGPISTIESILRSESVGITVNGHPVRYPQQPQGIPIFGNHFEIYPDHLGNHERLFNKYGSVIRTNNMGRVTYLTNDPDIAALAFRDNDYFTKAPSSASHPLYGIRDQTALFLCDTESPAWKEAHKFIPPSMTPRAVRHYTPLLQQSVDTVFNVLDKFDNNGQAFNVYHLTAKLASQVICQLVLGVDLHHFDAVDSPVHPIIVLLQRYLTLNRRVQTKGAWYSYLPFGDPVALKNTRRELYGLIEEAVITCQKKNGGTTGDLPIQTAALHATCLVDYLARATDEHGNKLRHEYILSNTLALVGAGFVTSSAFLSWLIYSLVEYPGQQDRLLQELVDHGAVSDKRWTYDEIQALPFLDAFVKEAQRMHSPSFQPARNVKKDIILPGGWALPQGSILIPSIPHLHHHTAYWENPDRFDPDRWRTEKVKNRHRSVYVPFAAGPRSCIGFNVALQEVKISLAELVYRYEFVNATNEGIEYDPDFIVIRPVNFYVRAIRRTEWPARSP
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of asperlin, a polyketide showing anti-inflammatory, antitumor and antibiotic activities (PubMed:30339758).  The first step of the asperlin biosynthesis is the production of the intermediate 2,4,6-octatrienoic acid by the highly redusing polyketide synthase alnA with cleavage of the PKS product by the esterase alnB (PubMed:30339758).  2,4,6-octatrienoic acid is further converted to asperlin via several steps involving the remaining enzymes from the cluster (PubMed:30339758).
What are the official names of this protein?
Cytochrome P450 monooxygenase alnD, Asperlin biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NPC2_ASPFU
Sequence: MKLISTAATLFVCLAPLSASARSISFFDSTQAPIQLETFPVKGDNPLVYCSDPSGNILQIESVDLVPNPPLPGQTLSINASGNLKERVEEGAYVALEVKYGLITLIKQTADLCEQIKNVDLECPLEKGEMTLTKQVDLPSHIPPGKYNVHADVYTKDGKKITCLDAHDIEFKIRP
What is the function of this protein?
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
What are the official names of this protein?
Phosphatidylglycerol/phosphatidylinositol transfer protein, PG/PI-TP.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
Protein: GLYA_BACCN
Sequence: MDHLKRQDEKVFAAIEAELGRQRSKIELIASENFVSEAVMEAQGSVLTNKYAEGYPGKRYYGGCEHVDVVEDIARDRVKEIFGAEHVNVQPHSGAQANMAVYFTILEHGDTVLGMNLSHGGHLTHGSPVNFSGVQYNFVEYGVDAETHRINYDDVLAKAKEHKPKLIVAGASAYPRVIDFKRFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPHAHFVTTTTHKTLRGPRGGMILCEEKFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQDDFKTYAQNIIHNAQRLAEGLQKEGLTLVSGGTDNHLILIDVRNLNITGKVAEHVLDEVGITVNKNTIPFETASPFVTSGVRIGTAAVTSRGFGLEEMDEIASIIAHTLKNHEDETALEEARKRVAVLTSKFPMYTDL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 057R_FRG3G
Sequence: MAMVSNVKYFADALQGTQGKVGTFTVLGENVFFKRGDGTDTVCGLEMVAGRILRARSDVHFCEPKYFVEMDDGEKVCSFELLDCKPLGSMAPGRKGKKSVGSVTQYLSGLYQTFAAAAAAHSVGVVHSDLHTGNVMLCPEPVSHYVYNLGGGEMLSLETNGVRAVVVDLGMARIPGKNTVACDIFVHVGHVVNGRPDYAADVRTLTLGSCYDMVMMCASGKPSLEERMLCYEVMAAYNNLFAGVCAPSKGGWFVDHYPSMCAVMEATIPDSVASRGGGSWLLAVANMCKLLVPRPYVKRACGKEKAHAMWMTLFTELGLTAKKSISKVDMVDAVQRLRAIADGSEIPPASLMKAACAVGLLTASVAEACYEKVEEIKASHVGMLRWKDALDAWVRLPVRCSGSVPKLGSTVILHTESGTEETVVTQSMLRQIVKTREALDMAQAASDAVWTDTAYYEADDELMKGAHEESAEDFATSFLKGGTTGPIAKRCRLILKSL
What are the official names of this protein?
Putative phosphotransferase 057R.
Protein: YA07_SCHPO
Sequence: MTVLTSYKLYCGPDFPAPLEKKEKREKGKIRNISFLIVLTKGPIWKVSSMESTSYNGCIENLDCKFRKSFIEEIIAYEGFGKYIEVINF
What are the official names of this protein?
Uncharacterized protein C5H10.07.
Protein: ATPE_FUSBL
Sequence: MAATLQFDLVSPERRLASVQATEVQIPGAAGDMTAMQGHAPTITTLRPGILRAVSAEGTKAYVVTGGFAEISATGVSVLAERAVPLDEMDAKLMDQLVADASAASSVGVDKDTAEKAMSDLQAMKAAAGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PTQB_ECO57
Sequence: MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLAGEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKKAAAN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2).
What are the official names of this protein?
PTS system N,N'-diacetylchitobiose-specific EIIB component, EIIB-Chb, IVcel, N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_INCEN
Sequence: AEKIKICLQKQVNSSFSLHNGFGGNLYATEEKRMFELVKPKAGASVLNQSTWICFGDSRTDQSNSAFPRSADVSAKTADKFRSLSGGSLMLSMFGPPGKVDYLYQGCGKHKVFYEGVNWSPHAAIDCYRKNWTDIKLNFQKSIYELASQSHCMSLVNALDKTIPLQVTKGVAKNCNNSFLKNPALYTQEVKPLEQICGEENLAFFTLPTQFGTYECKLHLVASCYFIYDSKEVYNKRGCGNYFQVIYDSSGKVVGGLDNRVSPYTGNTGDTPTMQCDMLQLKPGRYSVRSSPRFLLMPERSYCFDMKEKGLVTAVQSIWGKGRKSDYAVDQACLSTPGCMLIQKQKPYIGEADDHHGDQEMRELLSGLDYEARCISQSGWVNETSPFTEEYLLPPKFGRCPLAAKEESIPKIPDGLLIPTSGTDTTVTKPKSRIFGIDDLIIGLLFVAIVEAGIGGYLLGSRKESGGGVTKESAEKGFEKIGNDIQILRSSTNIAIEKLNDRITHDEQAIRDLTLEIENARSEALLGELGIIRALLVGNISIGLQESLWELASEITNRAGDLAVEVSPGCWIIDDNICDQSCQNFIFKFNETAPVPTIPPLDTKIDLQSDPFYWGSSLGLAITTPISLAALVISGIAICRTK
What is the function of this protein?
Binds to the N-acetyl-9-O-acetylneuraminic acid residues on the cell surface, bringing about the attachment of the virus particle to the cell.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induce an irreversible conformational change in HEF2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.  Displays a receptor-destroying activity which is a neuraminidate-O-acetyl esterase.  This activity cleaves off any receptor on the cell surface, which would otherwise prevent virions release.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell (By similarity).
What are the official names of this protein?
Hemagglutinin-esterase-fusion glycoprotein, HEF.
What is the protein family that this protein belongs to?
Belongs to the influenza type C/coronaviruses hemagglutinin-esterase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: TAL_SHIBS
Sequence: MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPTLLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_XYLFA
Sequence: MISSKASDYQQRIGYVFTDPSLLLQALRHCSAGTPHNERLEFLGDSVVNLLIAEALFQRWPRADEGALTRARSELVRETSLASIARTMQLGEQLILGPGELKSGGHRRDSILADAVEAVIAAIYLDADLATCRTVVLPWFETALTALPVGKPEKDPKTRLQEWLQARQWSLPVYELIFESGDPHTKHFRVSCTLGELKLRTEGEGSSRRLAEQDAASHAIDQLDSNK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_NITOC
Sequence: MAKRKSHSARWLREHFRDSYVIQAKAQGYRSRAVFKLQEIDTRERLLGPGRVVIDLGAAPGGWSQWAAERVGERGRVIAMDILPMLSCPGVQFIQGDFREDNVLAELQNTLAGCVVDLVMSDMAPNMSGMAAVDQPRAIYLGELALAFAQESLGPEGSFLLKTFQGEGFDALYEVIRQDFSRVRIHKPPASRGRSREVYIVARRSRKDNGGG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_CERS1
Sequence: MNANELTIAEARDALARGELSAVDLTMACLTAIDAGTPLNAFVHTTPEIALDQARAADARRGAGAGALNGIPLGIKDLFCTRGVASQAASNILRGFKPEYESTVTSKLFEAGAVMLGKLNMDEFAMGSSNETSCYGDAVNPWKVDDRRLTPGGSSGGSAAAVAADLCLAATGTDTGGSIRQPAAFTGIVGIKPTYGRVSRWGIVAFASSLDQAGPMTKSVRDAAILLGAMAGHDPKDSTSADIPVPDFEAALTGDIRGRKIGIPREYRMEGMPAEIEALWARGREMLADAGAEIVDISLPHTKYALPAYYVIAPAEASSNLARYDGVRYGHRARLGQGDGIVDMYEKTRAEGFGKEVQRRVMIGTYVLSAGFYDAYYNRARKVRALIKRDFDEAFAAGVDAILTPATPSSAFGLGEMADADPVAMYLNDVFTVTVNLAGLPGISVPVGLDAKGLPLGLQLIGRPWDEAGLLNHAHVLERAAGFVEKPRKWW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: COBQ_RHOCA
Sequence: MTALMIQGAGSNVGKSMLVAGLCRAARRRGLTVAPFKPQNMSNNAAVTADGGEIGRAQALQALACGLEPVTDMNPILLKPESDVGAQVVVQGKRLTTTRARDYATLKPQLMGAVLESFNRLKATHDLVIVEGAGSPAEVNLRAGDIANMGFARAADVPVVLVGDIDRGGVIAQIVGTQAVLDPADAEMISGFLINKFRGDVTLFDDGYRLIGARTGWRGFGTLPWFPLAHKLPAEDALDIASGPATGGTVIACLTLSRIANFDDLDPLAAEPGVRMVMVQPGQPIPAEARLVILPGSKSTRGDLAFLREQGWDIDLAAHVRRGGHVLGICGGYQMLGRSVADPEGIEGPAGTTPGLGLLDVETVMTPDKRLTRVRVRATHAGSGLAVEGYEIHIGRTEGADRARPFAIVEGQNEGAMSADGRVIGSYLHGLFGADAFRAAFLRGLGIRASGQSHAAGVEAALDALADHLETHLDVTGILALAR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity).
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: NAA35_RAT
Sequence: MVMKAAVDDDASGWELNVPEKMEKSSTSWVDITQDFEDACRELKLGELLHDKLFGLFEAMSAIEMMDPKMDAGMIGNQVNRKVLNFEQAVKDGTIKIKDLSLPELIGIMDTCFCCLITWLEGHSLAQTVFTCLYIHNPDFIEDPAMKAFALGILKICDIAREKVNKAAVFEEEDFQSMTYGFKMANGVTDLRVTGMLKDVEDDMQRRVKSTRSRQGEERDPEVELEHQQCLAAFSRVKFTRVLLTVLIAFTKKETSAVAEAQKLMVQAADLLSAIHTSLHHGIQAQNGTTKGDHPIMMGFEPLVNQRLLPPTFPRYAKIIKREEMVNYFSRLIDRIKTVCEVVNLPNLHCILDFFCEFSEQSPCVLSRSLLQTTFLVDNKKVFGTHLMQDMVKDALRSFVSPPVLSPKCCLYNNHQAKDCIDSFVTHCVRPFCSLVQIHGHNRARQRDKLGHILEEFATLQDEAEKVDAALHTMLLKQEPQRQHLACLGTWVLYHSLRIMIQYLLSGFELELYSMHEYYYIYWYLSEFLYAWLMSTLSRADGSQMAEERIMEEQQKGRSSKKTKKKKKVRPLSREITMSQAYQNMCAGMFKTMVAFDMDGKVRKPKFELDSEQVRYEHRFAPFNSVMTPPPVHYLQFKEMSDLSKYSPPPQPPELYVAASKHFQQAKMILESIPNADREVSRILKVAKPNFVVMKLLAGGHKKESKVPPEFDFSVHKYFPVVKLV
What is the function of this protein?
Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues.  Involved in regulation of apoptosis and proliferation of smooth muscle cells.
What are the official names of this protein?
N-alpha-acetyltransferase 35, NatC auxiliary subunit, Corneal wound-healing-related protein, Embryonic growth-associated protein, Protein MAK10 homolog.
What is the protein family that this protein belongs to?
Belongs to the MAK10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBX30_CAEEL
Sequence: MNPSTQIVVKMSNEELWKERYPNMEMISNSKRITPIFPEIKFKISGLEENSRYVLVLSLEKMDNIRYGINENKEWAPSSARKPKPHHNMKFFFHPEGTKLGKELMAETVEFTSVRITTSEKLSEKENVFYVHTMHKYVPVLTIRNLTTGEIASNIFKMEIAQFFPVSIYQQASMGRWKSDLNKHSTFGNRSEGGIKRKTSDAAGQLPSKRSSKKPVKKDVVDNSEVTLEVKTSQYLVNQNESNLTEYIPSSPLYSSQNQYQYPFHPYSPFDSSIPYPYSPMDYSYYFNPTFQSFSPENVYFDENRNPH
What is the function of this protein?
Involved in the regulatory network to control embryonic patterning and morphogenesis.  Implicated in negatively regulating vab-7 expression at the anterior of embryos.
What are the official names of this protein?
Putative T-box protein 30/42.
What are the subcellular locations of this protein?
Nucleus.
Protein: IL36B_MOUSE
Sequence: MMAFPPQSCVHVLPPKSIQMWEPNHNTMHGSSQSPRNYRVHDSQQMVWVLTGNTLTAVPASNNVKPVILSLIACRDTEFQDVKKGNLVFLGIKNRNLCFCCVEMEGKPTLQLKEVDIMNLYKERKAQKAFLFYHGIEGSTSVFQSVLYPGWFIATSSIERQTIILTHQRGKLVNTNFYIESEK
What is the function of this protein?
Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response.  Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor IL1RAP.  Stimulates production of interleukin-6 and interleukin-8 in synovial fibrobasts, articular chondrocytes and mature adipocytes.  Induces expression of a number of antimicrobial peptides including beta-defensin 4 and beta-defensin 103 as well as a number of matrix metalloproteases (By similarity).  Seems to be involved in skin inflammatory response by acting on keratinocytes, dendritic cells and indirectly on T-cells to drive tissue infiltration, cell maturation and cell proliferation.  Induces the production of pro-inflammatory cytokines in bone marrow-derived dendritic cells (BMDCs), including IL-12, Il-1 beta, IL-6, TNF-alpha and IL-23, and activates p38 MAPK phosphorylation in BMDCs.  Involved in dendritic cell maturation by stimulating the surface expression of CD80, CD86 and MHC class II.  Induces the production of IFN-gamma, IL-4 and IL-17 by T-helper 1 (Th1) cells, cultured CD4(+) T-cells and splenocytes.
What are the official names of this protein?
Interleukin-36 beta, Interleukin-1 family member 8, IL-1F8.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
Protein: I20RA_HUMAN
Sequence: MRAPGRPALRPLPLPPLLLLLLAAPWGRAVPCVSGGLPKPANITFLSINMKNVLQWTPPEGLQGVKVTYTVQYFIYGQKKWLNKSECRNINRTYCDLSAETSDYEHQYYAKVKAIWGTKCSKWAESGRFYPFLETQIGPPEVALTTDEKSISVVLTAPEKWKRNPEDLPVSMQQIYSNLKYNVSVLNTKSNRTWSQCVTNHTLVLTWLEPNTLYCVHVESFVPGPPRRAQPSEKQCARTLKDQSSEFKAKIIFWYVLPVSITVFLFSVMGYSIYRYIHVGKEKHPANLILIYGNEFDKRFFVPAEKIVINFITLNISDDSKISHQDMSLLGKSSDVSSLNDPQPSGNLRPPQEEEEVKHLGYASHLMEIFCDSEENTEGTSLTQQESLSRTIPPDKTVIEYEYDVRTTDICAGPEEQELSLQEEVSTQGTLLESQAALAVLGPQTLQYSYTPQLQDLDPLAQEHTDSEEGPEEEPSTTLVDWDPQTGRLCIPSLSSFDQDSEGCEPSEGDGLGEEGLLSRLYEEPAPDRPPGENETYLMQFMEEWGLYVQMEN
What is the function of this protein?
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24.  The IL20RA/IL10RB dimer is a receptor for IL26.
What are the official names of this protein?
Interleukin-20 receptor subunit alpha, IL-20 receptor subunit alpha, IL-20R-alpha, IL-20RA, Cytokine receptor class-II member 8, Cytokine receptor family 2 member 8, CRF2-8, IL-20R1, ZcytoR7.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SEPF_STRP6
Sequence: MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRASSHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMSTSSIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQARRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RS17_BUCBP
Sequence: MIDKFRTLSGQVISNKMQKSAIVSIKRLIKHPLYKKFVKKTTKLCIHDENNQCSFGDIVEIRECRPISKTKSWMLVRISKKSLRS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS12_PROA2
Sequence: MPTIQQLIRRGRTTKASKTASPALEKCPQKRGVCTRVYTTTPKKPNSALRKVARVRLSNKIEVTAYIPGEGHNLQEHSIVLIRGGRVKDLPGVRYHIVRGSLDTSGVADRRQGRSKYGAKRPKGAAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: BAMA_SHIB3
Sequence: MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGNLAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKTVKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKSYGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFKTDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDDHKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNYDPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWDMGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: KAE1_THEPD
Sequence: MLFGMRALKVLGIESTAHTFGVGIATSSGDILVNVNHTYVPRHGGIKPTEAAEHHSRVAPKVLSEALQKAGISVEEVDAVAVALGPGMGPCLRVGATLARYLALKFGKPLVPVNHAIAHLEISRLTTGLEDPVFVYVAGGNTMVTTFNEGRYRVFGETLDIPLGNCLDTFAREVGLGFPGVPRVEELALKGREYIPLPYTVKGQDVSYSGLLTHALSLYRSGRARLEDVCYSLVETAYSMLVEVAERALAHTGKSQLVLTGGVARSRILLEKLRRMVEDRGGVLGVVPPEYAGDNGAMIAYTGALAFSHGVRVPVEESRIQPYWRVDEVVIPWRSR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMDE2_XENLA
Sequence: MRPTEACCYLKISLIILFYMGCYAQKHPNMDIAVILVGTTEEVAIKDVHEKDDFHHLPVTPRVALVTMNESDPKSIITRICDLMSDKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIMADKEEASMFFQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENKVRSTIENSFVGWELEEVIHLDMSLDDIDSKIQNQLKKLQSPVILLYCTKEEATYIFEVAHSVGLTGYGFTWIVPSLVAGDTDTVPDEFPTGLISVSYDEWDYDLPARVRDGIAIITTAASTMLSEHNSIPQSKSSCNNIQESRVYEAHMLKRYLINVTFEGRNLSFSEDGYQMHPKLVIILLNQERKWERVGKYKDRSLKMKYYVWPVFDLYPNSEEHKDEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQIRPENRTEEGGNYIKRCCKGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGTWNGMIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAVAVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMIQEEYVDQVSGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNNYLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFFWQLRHCFMGVCSGKPGMVFSISRGIYSCIHGVAIEDRQSALDSPSATMNNTHSNILRLLRTAKNMANLSGVNGSPQSALDFIRRESSVYDISEHRRSFTHSDCKSFQPEENLFSDYISEVERTFGNLQLKDSNVYQDHFHHHRPHSIGSNSSIDGLYDCDNAPFTTQPRSLSKKPLDIGLPSKHPSPQIGDLYGKFSFKSDHYGAPDDLIRSDVSDISTHTVTYGNIEGNAKRRKQYKDSLKKRPASAKSRREFDEIELAYRRRQRSPDHKRYFRDKEGLRDFYLDQFRTKENNPHWEHVDLTHIYAERADDFKHDTSCSNRQHQKHVGEFVQTDRKHGSGGNAWEKNMSNIEWEDRASSNFCRNCPSKMHNYTGQNTNRPACIRCEVCKKAGNLYDISEDNSLQDLEARPIQAPNSKYPQSPNGKAQKRNRSKLHRQHSYDTFVDLQKEDVTLAPRSVSLKDKERFLDGSPYAHMFEMPNETSFTSKSHGPTHNPGGYMLSRSLYPDRVTQNPFIPTFGDDQCLLHGSKPYYFRQPAIGGLKGRADFRGAGKSLSAQHSGPSGHFQKDICIGNQPNACVSNNKNPRSFNNSTNGHVYEKLSSIESDV
What is the function of this protein?
Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:18177891, PubMed:25008524, PubMed:28232581).  Sensitivity to glutamate and channel kinetics depend on the subunit composition (Probable).
What are the official names of this protein?
Glutamate receptor ionotropic, NMDA 2B, GluN2B, N-methyl D-aspartate receptor subtype 2B, NMDAR2B, NR2B.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2B/GRIN2B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.