PharMolix/UniProtQA huggingface dataset:
Protein: CRCB_CAMFF
Sequence: MSFTTIFYIGFGGALGAILRSFTNGFVSKIFPNLSFPLGTLSVNIIGGFFIGFLMSLASNINIDINLKSFLVTGFLGGLTTFSTFSYENMLLLQSGNYTNAFLNIASNLLLSLLFCYFGFWIVKVMYA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y1571_GEOKA
Sequence: MAKSFYRYLLRFRHGHQEDPVVRFANGAYEDHSFPKGSTDYEELSGYLELNGDYLESMVVFDELWEQFLHEA
What are the official names of this protein?
UPF0346 protein GK1571.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: ENGB_FRAP2
Sequence: MNYTKAKYIMGAAKVSQLPEDTGVEVAFAGRSNAGKSSALNTLTDQKGLARVSKTPGRTQLINLFDLGDNKRLVDLPGYGYAKVSEAIKKQWQSEMENYLTTRKCLGGIVLLVDSRHELKEFDSLMIEMAISFDLNLHILLTKADKLNNKERAQANKMIESFLKTFIRTDKISYQLFSSLSKMGLDKLKEKLDIWYQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: YKR18_YEAST
Sequence: MFKVFGFGAKEEIPELSQEEKTKAILKQAHDFEQALRAMDYVLDDNADEGLALLDESDAKEASDQTINALARGVIEFLEATLGFEAEEMKKASATLAKAEALSLKSRERAQKIGLKSSSLYPPGTVYAVTYTESCLLHALLMIFSESMMEAAKAILKLRKSYYMLQEILETIKAANKAKKLKITSGSEDKESTPATFITGGDAFNSVDIPYELTPEEQKDKDLLQFAEQIHSMRTERLSGAHIGNSPAINRLRGELGLQAMEDLPEEEITDHKVLSDDIDLSQATIDEFVHSGVNLCFGILQVVISLLPPAIGAVLSVVGFRGSREEGLRLVWKATKQRNVHGCIGLLALMFYYDGPFQFTDDDFDIPAAVKDSSNSEDSEDEEMDGPTLLHPGKILEDALLQSRALFPNSALWLLNEARMLSGKGRLEEAVALMDSIDVSKIRMRQVKSLMIFDRAITLIHLHQYDRAAEDILSLLDISDWSHAFYTYFAGCCYLENWRMCEMGLMKSDKKDEYQKKAEELIFTSVNLLGKKTFKSKNLPLDRFILRKVEQFKAKKEELGVENPLDGIATSPVHEIAYFYNGYNRMSEEHLELTKKMLTEYRNPAIEALDSDQELIKDLLVSLTLRRLGHIQEGCDILDEKVLPKFFSIQNGKVKYIKKTEDPWAYPTALYERALFTWKLEGMDGLPESKEWLLRAQGYADDYELSTRVGMKIKAAIDRVDHSL
What are the official names of this protein?
IML2-like protein YKR018C.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LEXA_SHESH
Sequence: MRPLTPRQAEILELIKRNIADTGMPPTRAEIAKRLGFKSANAAEEHLKALAKKGCIEIIPGTSRGIRLTQANESEEELGLPLIGQVAAGEPILAQEHVEQHYQIDPAMFRPSADFLLRVRGDSMKNIGILEGDLLAVHKAEQARNGQVVVARVEDDVTVKRFEKKGSIVYLHAENEDYSPIVVDLTSESLSIEGLAVGVIRNGDWQ
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RIPT_TRIKI
Sequence: MIRFLVLSLLILTLFLTTPAVEGDVSFRLSGATSSSYGVFISNLRKALPNERKLYDIPLLRSSLPGSQRYALIHLTNYADETISVAIDVTNVYIMGYRAGDTSYFFNEASATEAAKYVFKDAMRKVTLPYSGNYERLQTAAGKIRENIPLGLPALDSAITTLFYYNANSAASALMVLIQSTSEAARYKFIEQQIGKRVDKTFLPSLAIISLENSWSALSKQIQIASTNNGQFESPVVLINAQNQRVTITNVDAGVVTSNIALLLNRNNMAAMDDDVPMTQSFGCGSYAI
What is the function of this protein?
Inactivates eukaryotic 60S ribosomal subunits.
What are the official names of this protein?
Ribosome-inactivating protein alpha-trichosanthin, Alpha-TCS, rRNA N-glycosidase.
What is the protein family that this protein belongs to?
Belongs to the ribosome-inactivating protein family. Type 1 RIP subfamily.
Protein: RPIA_METMA
Sequence: MTERNTSTDSPEKRAAGIAAAGLVSSGMVVGLGTGSTVAYTIKELGRRVKEEGLDILGVVTSYQSEMLAIDAGIRLTTLSQDPELDIAIDGADQIDSNLYTIKGGGAAHTREKIVSVSAKRFVVVADDSKTSTQLDKPVPVEVLPFAKEPAVNRIRKLGGEPRLRSAVKKDGPVITDNGNFVLDVEFGVIKDPEALALQLSAVPGVVEHGIFSNVDELYIGKKDGSVKIISRQK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: TP1B_HADIN
Sequence: NECIRKWLSCVDRKNDCCEGLECYKRRHSFEVCVPIPGFCLVKWKQCDGRERDCCPGLECWKRSGNKSSVCAPIT
What is the function of this protein?
This toxin potently and selectively inhibits ASIC1a, an isoform of the gene ASIC1.  It incompletely inhibits ASIC1a activation in a pH-independent and slowly reversible manner.  This toxin acts by binding to and stabilizing the closed state of the channel, thereby impeding the transition into a conducting state.  This toxin may bind to the acidic pocket of ASIC1a, since mutation of a key residue of this pocket (Arg-350) abolishes the ability of the toxin to inhibit ASIC1a.  In vivo, this toxin protects the brain from neuronal injury when administered up to 8 hours after stroke onset.
What are the official names of this protein?
Pi-hexatoxin-Hi1b, Pi-HXTX-Hi1b, Double-knot toxin, DkTx.
What is the protein family that this protein belongs to?
Belongs to the psalmotoxin-1 family. Double-knot toxin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRHO_ACIBY
Sequence: MEFSMNATVEQLAPVEQQATAGWVVAALYQFKEVQDPADLQQRLLDLVKTINLCGTLIVAGEGINGTVAGDREAIDTIHQFLLNEGFNAMEYKESHSSDKPFRKMKIKLKKEIVTLGVEVKPRDLVGHYLDPKEWNELIARDDVILIDTRNDYEYKAGTFKGAIDPKTETFREFPEYVKKELEQHKDKKIAMFCTGGIRCEKSTSLLLQEGFKEVYHLKGGILKYLEETPPDESLWEGECFVFDGRTAVTHGVEEGANIKCHACGWPLTPEESALPSYEHGVSCLYCIDKTTEKQKAGFRMRQSQIAAAKRKRL
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: YNE4_CAEEL
Sequence: MQDPNTFLLIPLIQSERKRKIFTKCQENGELSGMVHSEKETTELQFKRFYCSASKIPDQLMKDIVEQCIKDSEYAENLCNNVFNNEIVTSHEIRYKFQINVLKNLISELQANNVVVPDSMFDRLGSLMGMKEGEYVERVYLTDGGDKVLAKFSEAVNQLSMGTTGLSVWQASCDLANLFRLIPSEYNRILELGSGCGVSGIAIAKMNDCCVTLTDYDDNVLNLLEENIAKNDLKSDTEDSSANNNQATVRSLNWCDFDFSEWKEPTDLIIAADVVYDTALLASLCNVLNLLLRHSKAAIVACTRRNESSIECFEHHLKMAKLEIVEKFEYENGAYTIGENSYHYASIFPFFSTLKTPTIFYNIQPKNKLVF
What are the official names of this protein?
Uncharacterized protein R08D7.4.
Protein: UXAB_ENT38
Sequence: MNTLNRRDFPGALYPERIIQFGEGNFLRAFIDWQIDLLNEHTDLNSGVVIVRPIKSDFPPSLSVQDGLYTTIIRGLNEQGEAVSDARLIRSVNREISVYSQYDEFLKLAHNPDMRFVFSNTTEAGISYHAEDKFDDAPAVSYPAKLTRLLFERFSHFNGAADKGWVIIPCELIDYNGDALRELVLRYAQEWALPAEFTQWLNDANAFCSTLVDRIVTGYPRDEVTALETELGYHDGFLDTAEHFYLFVIQGPKSLASELRLDKLSLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEVCAFVEKAIYQEIIPVLDLPKDELESFASAVTGRFRNPYIKHQLLSIALNGMTKYRTRILPQLLAGQKATGKLPARLTFALAALIAFYRGERNGESYPVQDDQHWLDRYQQLWAQHHDKQISTSELVKAVLSVSEHWEQDLTNVSGLVEQVTLDLDAILLQGMRAAVKQLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: SAHH_HALWD
Sequence: MSAYSPLSAQLDADTDVDVESTRTEGRRKMEWTLQHMPILQELRARFAETKPLAGETIGMAMHVEAKTANLVELLALGGAEVAITGCNPLSTHDDVSAALDSNENVTSYAKRGVDEEAYYDAIEAVVAHEPTITIDDGMDMVYAIHEDHPDLLDTIIGGAEETTTGVHRLRAMDEDDELQYPVFAVNDTPMKRLFDNVHGTGESALATIAMTTNLSYAGKNVVVAGYGYCGKGVAQKAAGQNANVIVTEVEPRRALEAHMEGYEVMPMNEAATRGDVFVTTTGNRDVITQEDFEVMSDGAILANAGHFDVEINLEELSELAIDTYEARDGVQAYELGDGRRLNVLAEGRLVNLAAPIALGHPAEVMDQSFGIQAVCVRELIENKSSYDAGVHNVPDELDREVAEIKLKAEGVDIDSLTQTQSEYLDSWSHGT
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBSB_PROM3
Sequence: MDRTLIQEILEVVEQAAIASAHLTGLGKKDEADAAAVEAMRKRMGKIEMQGRIVIGEGERDEAPMLYIGEEVGSGSGPGVDFAVDPCEGTNLCANNQRGSMAVLAASDRGGLFNAPDFYMKKLAAPPSAKGKVDIRKSATENINILSQCLGLAVSELTIVVMDRARHKGLISEIRATGARVQPISDGDVQAAIACGFAGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQTSEWADYTKEGNIARLNEMGITDVDKIYEAEELASGNNVVFAGSGITDGLLFHGVKFEPDCTRTSSLVISTLDNTARFTNTVHIKDGAKSIALS
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.
What are the official names of this protein?
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, FBPase class 2/SBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
Protein: RPOA_SOLM1
Sequence: MLTRNGQRLINSRNWTELVKPEVLDKDPSSTETFGRFVCEPLERGFGTTLGNALRRVLLSSLQGAAIVAARIEGVQHEFSTIPGVIEDVTEIILNLKQVRLAMATDEPQRLTLLAKEKGEVRASAIQGNHNVSVLSEDVLIATLSEDRDFRIDLEVRMGKGYVPADMHEGLESEIGLILLDASFSPVKKVAYTIEQARVGQMTNYDKLVLEVTTDGSIAPEDAISYSAKILKDQLTVFINFDEKESEAEKNRRRDDIELNPSLFKSIDELELSVRATNCLKSANIQTVGELMQKTEHEMLKTKNFGKKSFEEIRRVLEDMGLEFGMRIENFDQKYQEWLKRKQTDEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PXPA_VIBC3
Sequence: MSKRTIQLNCDMGESFGVWTMGADEEVMPWIDMANIACGFHASDPHVMSRTIDLALEHEVMIGAHPSYPDLQGFGRRSLAMNEQEVSEIILYQVGALKALCESKNGQLSYVKPHGALYNDMMSDPSIFRAVVDAVSCFNLPLMVLASANNQDYLDIADRFDVPLLFEAFADRTYLANGKLTPRSQPNAVLSSEEAILNQVRQIARYGKVTSSDGFVIPIEADTLCVHGDNPNAVSLIARIRAALDE
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: NUON1_OPITP
Sequence: MNLEAVKHAASLNEWSGLIPEIALGCLALLLLVVEMVLPKKRHDLIATIAIIGQFGILGWVAWDFHSPFLGRNDAFSGLLQFSYVGQAMRVFFLLSSIFVSILARVSLAKQQLPRIEFYHIVLVATAAMMLLAQANHFVLFFVALETLTVGLYILVSYFRTSPLSLEAGLKYLIMGALSSSLLLFGIVLLYGVAGNPALEGHTADPMNFAALTRFLALNPDNFLAAAGIVLVLSGIAFKIGAFPFQIWIPDVYQGAPTPTTAFLAVSSKAAGFAILLVLVNSVFGPYWWLVQPVLVAMAVATILFGNIAALTQHNVKRLIGLSGVSHAGFLLIGIIASHSVPSAVGAVLFYLFAYLLATFAVFGVMAHLAGADDAEQELDHYAGLAKEDPFLAAILAVALGSLAGIPPLAGFMGKLFVFIAAFKAGFYGLLAVAIVGVVISIYYYFGWIKAAFFETWTPPADAVNPRPARTPVGAAAGVALATLALCSILFGVYQGPLGAWLLAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N 1, NADH dehydrogenase I subunit N 1, NDH-1 subunit N 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DCS2_YEAST
Sequence: MGSQDLASLIGRFKYVRVLDSNPHTKVISLLGSIDGKDAVLTAEKTHFIFDETVRRPSQSGRSTPIFFHREIDEYSFLNGITDLKELTSNDIYYWGLSVLKQHILHNPTAKVNLIWPASQFHIKGYDQQDLHVVRETPDMYRNIVVPFIQEMCTSERMKWVNNILYEGAEDDRVVYKEYSSRNKEDGFVILPDMKWDGINIDSLYLVAIVYRDDIKSLRDLNPNHRDWLIRLNKKIKTIIPQHYDYNVNPDELRVFIHYQPSYYHFHVHIVNIRHPGVGEERGSGMTILLEDVIEALGFLGPEGYMKKTLTYVIGENHDLWKKGFKEEVEKQLKHDGIATSPEKGSGFNTNLG
What is the function of this protein?
Plays a role in the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.  Stress-induced regulatory protein that modulates the m7GpppX diphosphatase activity of DCS1.
What are the official names of this protein?
Inactive diphosphatase DCS2, Histidine triad protein, Protein Dcs2p.
What is the protein family that this protein belongs to?
Belongs to the HIT family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, P-body. Note=Predominantly cytoplasmic. Localizes close to the perinuclear space before the diauxic growth shift. Recruited to the P-body after the post-diauxic growth shift. Colocalizes with the decapping activator protein LSM1 at P-body.
Protein: TM222_HUMAN
Sequence: MAEAEGSSLLLLPPPPPPPRMAEVEAPTAAETDMKQYQGSGGVAMDVERSRFPYCVVWTPIPVLTWFFPIIGHMGICTSTGVIRDFAGPYFVSEDNMAFGKPAKYWKLDPAQVYASGPNAWDTAVHDASEEYKHRMHNLCCDNCHSHVALALNLMRYNNSTNWNMVTLCFFCLLYGKYVSVGAFVKTWLPFILLLGIILTVSLVFNLR
What are the official names of this protein?
Transmembrane protein 222.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: RL31B_PSYCK
Sequence: MRKDIHPNYQEVLFHDTNADVFFLTRSTVKTKTTREYEGSEYPYYPLDISSASHPFYTGEQRKTSTEGRVASFNKRFGAFGGRKKAADADAAE
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: NAHB_PSEU8
Sequence: MGNQQVVSITGAGSGIGLELVRSFKSAGYYVSALVRNEEQEALLCKEFKDALEIVVGDVRDHATNEKLIKQTIDRFGHLDCFIANAGIWDYMLSIEEPWEKISSSFDEIFDINVKSYFSGISAALPELKKTNGSVVMTASVSSHAVGGGGSCYIASKHAVLGMVKALAYELAPEVRVNAVSPGGTVTSLCGPASAGFDKMHMKDMPGIDDMIKGLTPLGFAAKPEDVVAPYLLLASRKQGKFITGTVISIDGGMALGRK
What is the function of this protein?
Catalyzes the oxidation of naphthalene dihydrodiol into 1,2-dihydroxynaphthalene.
What are the official names of this protein?
1,2-dihydroxy-1,2-dihydronaphthalene dehydrogenase, Cis-naphthalene dihydrodiol dehydrogenase, Dibenzothiophene dihydrodiol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PXPA_STAA1
Sequence: MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENVMNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNDEIYNLMIYQLGALQGFCRIHQLKINHVKPHGALYQMGAKDREIANVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLITASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQADTICVHGDGEHALLFVSKIREILMKEGIDIQSL
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: PDYN_RAT
Sequence: MAWSRLMLAACLLVIPSEVAADCLSLCSLCAVRTQDGPHPINPLICSLECQDLVPPSEEWETCRGFWSFLTLTASGLHGKDDLENEVALEEGYTALTKLLEPLLKELEKGQLLTSVSEEKLRGLSSRFGNGRESELLGTDLMNDEAAQAGTLHFNEEDLRKQAKRYGGFLRKYPKRSSEMTGDEDRGQDGDQVGHEDLYKRYGGFLRRIRPKLKWDNQKRYGGFLRRQFKVVTRSQENPNTYSEDLDV
What is the function of this protein?
Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
What are the official names of this protein?
Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin.
What is the protein family that this protein belongs to?
Belongs to the opioid neuropeptide precursor family.
What are the subcellular locations of this protein?
Secreted.
Protein: P17_ASFWA
Sequence: MDTETSPLLSHNLSTREGIKQSTQGLLAHTIAKYPGTTAILLGILILLVIILIIVAIVYYNRAVDCKSSMPKPPPSYYVQQPEPHHHFPVFFRKRKNSTSQQSHIPSDEQLAELAHS
What is the function of this protein?
Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid.  Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane.  Required for the assembly of the capsid and icosahedral morphogenesis.  Additionally, inhibits the host cGAS-STING pathway through its interaction with STING1 and subsequent interference of the recruitment of downstream components TBK1 and IKBKE.
What are the official names of this protein?
Minor capsid protein p17.
What is the protein family that this protein belongs to?
Belongs to the asfivirus minor capsid protein p17 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host endoplasmic reticulum membrane; Single-pass membrane protein. Note=Found in the inner envelope of the virus.
Protein: RBBP5_CAEEL
Sequence: MVEILDRTYGAQFPEELECHLDLQNASANCCKFNRWGSIVAVGCTDGRVLIYDFMTRNIARTFSAHCLPVSCLSWSRDGRKLLTSSADNSIAMFDVLAGTLLHRIRFNSMVTFAMFHPRNDNKAIVLQVNKQPTVEQFSPRIQTVLANDTPGSSDESASCVSYDRKGKYIIAGTGKGKLLIYNAETLKCVAWCKQNTVQQIRQIIVPMKSRFIITNTQDRVIRTYELEDLLHQRGQMVEAKYKVLDMVNKAAWKNVCTDSDGLYVCGASTKAHSLYIWESNTGSLIKILHGNKGEALLDVQWHPTRPIILSIAQGTVSMWTQAHVENWSAFAPEFQELEENEKYIEKENEFDMEDEDADEDMTSKSQDAEDDIIDVVNVRPEDYLASSDEEDCNIMKPARNLESGPLWYIPVPLDIENADNDQRLPDDIRNLDNLLNPAWVASAKGYELSPKSK
What is the function of this protein?
Required for di- and trimethylation at 'Lys-4' of histone H3.  Regulates left/right asymmetry of ASE sensory neurons, via its role as a component of the SET2 complex (PubMed:21698137).
What are the official names of this protein?
Retinoblastoma-binding protein homolog 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: ALGC_PSESM
Sequence: MNSPASVAPILPDTIFRAYDIRGVVEDTLNAETAYWIGRAIGSESLAQNEPNVSVGRDGRLSGPELVQQLIQGLHDSGCHVSDVGLVPTPALYYAANVLAGKTGVMLTGSHNPKDYNGFKIVIAGDTLANEQIQALHERIKTNNLTSQKGSITQVNILDRYFKQIKDDIVMARKLKVVVDCGNGAAGVIAPQLIEALGCEVISLFAEVDGNFPNHHPDPGKLENLQDLIAKVKETGADLGLAFDGDGDRVGVVTNAGNVVYPDRLLMLFALDVLKRNPGADIIFDVKCTRRLTPLISEHGGRPVMWKTGHSLIKKEMKKSGALLAGEMSGHIFFKERWFGFDDGIYSAARLLEILSQEPANAEDLFETFPNDISTPEINIKVTDVTKFSIIEALEKDAQWGDAKLTTIDGVRVDYPKGWGLVRASNTTPVLVLRFEAETQAELERIQGVFHAELKKVAPDLDLPF
What is the function of this protein?
The phosphomannomutase activity produces a precursor for alginate polymerization.  The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics.  Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity.  Essential for biofilm production (By similarity).
What are the official names of this protein?
Phosphomannomutase/phosphoglucomutase, PMM / PGM.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NAS35_HAECO
Sequence: MSLLRSASLLLVVVTAALPPCTLGYSLHDGSRLDDVIAEFTAERRPRRLATPAQRRLMGLTEEQHKTVQFYLDKLRELGNRRHPESYNKDSPKNEAYKWRKQMRDDLKTELLNPEKYGRHFEGDIILFPEQAKQIYENALKTGQRRVKRKFIGSDLRRWDPTRPIIYSFDGSHTSREQRIIELALEHRHNITCLNFVRNDNANKGNRIVFTDVDGCASNVGRHPLGEEQLVSLAPECIRLGVIAHEVAHALGFWHEQSRPDRDQFVNVRWENIDKDSKGQFLKEDPDDVDNAGVPYDYGSIMHYRSKAFSRYDDLYTISTFVTDYQKTIGQRDQLSFNDIRLMNKIYCSNVCSRKLPCQRGGYTDPRRCDRCRCPDGFTGQFCEQVMPGYGAVCGGRIQVNSGWTRFSSPGYPREFKEGQECSWLLVAPPGQVVEMQFIGEFEMYCKVRHSLCMDYVEVRNSTDFANTGMRYCCYGTPSTSIRSATTDLVVLFRSFYRGGRGFEARARALPANGQWASWTPWTPCTASCGACGSRMRTRVCPHGACPC
What is the function of this protein?
Metalloprotease which cleaves the carboxyl terminus of procollagens to mature collagens.  Probably involved in cuticular collagen maturation.
What are the official names of this protein?
Zinc metalloproteinase dpy-31, Nematode astacin 35, Procollagen C-proteinase.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_VIBAN
Sequence: MDENKQKALAAALGQIEKQFGKGSIMRLGDNRTMDVETISTGSLSLDIALGAGGLPMGRIVEVYGPESSGKTTLTLELIAAAQRVGKTCAFIDAEHALDPIYAKKLGVNIDELLVSQPDTGEQALEICDALARSGAIDVIVIDSVAALTPKAEIEGEMGDSHMGLQARMLSQAMRKLTGNLKQSNCMCIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRTGSIKEGDEAVGNETRIKVVKNKIAAPFKQADTQILYGQGFNREGELVDLGVKHKLVEKAGAWYSYNGDKIGQGKANACKFLRENPAAAMALDTKLREMLLNPAELIVEEPILSEMPQEEEL
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_FRATT
Sequence: MSQFNQNNKQIDVMGIRKILPHRYPFALLDKIVDWSVEDRTIVAQKNVTINEDFFNGHFPDFPVMPGVLIVEAMAQATAILGELMAETLFAHVVEKAGGGRRTFMLAGIDKVRVKRPVVPGDVLVIESRMVKQKNIICTAESVAKVDGQIVCSAELMAAYKDY
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_AZOSB
Sequence: MKTTFLDFEQPIAELEEKIEQLRFVQDDSAVDISEEIARLEVKSQALTKDLYAKLTPWQIAQVARHPQRPYTLDYVQHIFTDFEELHGDRAYADDKAIVGGLARFNGQSCVIIGHQKGRDTKEKIARNFGMPRPEGYRKAMRLMKLAEKFGLPVFTFVDTPGAYPGIGAEERGQSEAIGHNLYVMAELKVPLICTVIGEGGSGGALAIAVGDQVMMMQYSTYSVISPEGCASILWKSAEKASEAAETMGITAARLKSLGLVDKVVNEPVGGAHRDHRAAAQSLKRALAEALRQVDTLSPSELVEQRMEKLMGYGRFKEIAA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_SYNJA
Sequence: MSKEDAIEVEGVVTESLPNAMFRVDLDNGFNVLAHISGKIRRNYIKILPGDRVKVELSPYDLNKGRITYRLKKK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGB_BORHE
Sequence: MNIFEMSVDLAHRYLDVLSLRQSVIADNIANVDTPNFKRSKVTFEAELERAILNERASNLSLIRGNDKNLNGFKELGYLDVKPSRMLDYLSILKNDGNNVDIDSEMKNLIQNQMIYSLFTNIQAHHFKSVNIVIK
What is the function of this protein?
Structural component of flagellum, the bacterial motility apparatus.  Part of the rod structure of flagellar basal body (By similarity).
What are the official names of this protein?
Flagellar basal body rod protein FlgB.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: Y3835_GLOVI
Sequence: MRSPLPPMPDPEAFPPGAVSVDAGGITLTVWAQPRASCSEVVGWQQNAFKVRLAAPPVEGKANAECVALIAAFFGVPRRQVSLVQGQQGRHKKIRIEAPADLLLVALQKLS
What are the official names of this protein?
UPF0235 protein glr3835.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.