PharMolix/UniProtQA huggingface dataset:
Protein: SYE_STAAM
Sequence: MSDRIRVRYAPSPTGYLHIGNARTALFNYLYAKHYNGDFVIRIEDTDKKRNLEDGETSQFDNLKWLGLDWDESVDKDNGYGPYRQSERQHIYQPLIDQLLAEDKAYKCYMTEEELEAEREAQIARGEMPRYGGQHAHLTEEQRQQFEAEGRQPSIRFRVPQNQTYSFDDMVKGNISFDSNGIGDWVIVKKDGIPTYNFAVAIDDHYMQISDVIRGDDHISNTPKQIMIYEAFGWEPPRFGHMSLIVNEERKKLSKRDGQILQFIEQYRDLGYLPEALFNFIALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPAFFDKQKLAWVNNQYMKQKDTETVFQLALPHLIKANLIPEVPSEEDLSWGRKLIALYQKEMSYAGEIVPLSEMFFKEMPALGEEEQQVINGEQVPELMTHLFSKLEALEPFEAAEIKKTIKEVQKETGIKGKQLFMPIRVAVTGQMHGPELPNTIEVLGKEKVLNRLKQYK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_COXBR
Sequence: MNETEKSTHFGYQTVPTDQKTDKVKHVFESVAAKYDLMNDLMSLGIHRCWKDFAITQCRLRTGQRILDLAGGTGDLAKRISPLVGDEGEVVIADINAAMLNVGRRRLLDQGIFRNIQFIQADAEKLPFPNNFFDRIVIGFGLRNVTNQLAALQSMHRVIKPGGFVVILEFSKPTLAPLKAVYDAYSFQLLPRLGKLVAKDEESYRYLVESIRMHPDQEALLSKMTDAGFEDCDYHNLSGGIVAVHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: VP16_GAHVM
Sequence: MEANMSFENDYYSPIQLFAEIEAYANTMDKSPDLDILRTIEEFDETLLSEIEVRTQSIPSPLVAPSVTKMSLPSPSPAPPNSLYTRLLHELDFVEGPSILARLEKINVDLFSCFPHNKHLYEHAKILSVSPSEVLEELSKNTWTYTALNLNEHGEMALPMPPTTKADLPSYVDDIQNFYLGELEAREKSYATMFYGYCRALAEYIRQSAIKDLRDARVEDKNIGACSKARQYIAERYYREAARFAKLLYVHLYLSTTRDVSQRLEASQMGRQNIFVYLKCEWLQERHFHCLFQPVIFNHGVVIVEGRVLTAPELRAQNYIRSEFGLPLIRCKLVEEPDMPLISPPPFSGDAPRASVYLLQCIRSKLEVYSLSHPPNPQLHVHKEHVHVQKLESPPNYGTTVEALLMDSSDRNSISPGDPVATTISTL
What is the function of this protein?
May play a role in the aggregation of tegument proteins around nucleocapsids during virus morphogenesis.
What are the official names of this protein?
Tegument protein VP16 homolog, Alpha trans-inducing protein, Alpha-TIF, ORF10 protein, Tegument protein 10.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae tegument protein VP16 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.
Protein: SYK_PSEMY
Sequence: MSDQQLDQPSLSHEERQHEENKLIAQRKEKLAAVREQGIAFPNDFRRDSLCGELQKQYEGKSKEELEAAAIPVKIAGRIMLNRGAFMVLQDTSGRLQVYVDRKGLPAETLEAIKTWDLGDIIAAEGTLARSGKGDLYVNMTSVRLLTKSLRPLPDKHHGLTDTEQRYRQRYVDLIVNEETRHTFRVRSQVIAHIRRFLNERGFLEVETPMLQTIPGGAAAKPFETHHNALDMQMFLRIAPELYLKRLVVGGFEKVFEINRNFRNEGVSTRHNPEFTMLEFYQAYADYRDNMDLTEELFRELALAVLGTTDVPYGDKVFHFGEPFVRLSVYDSILKYNPDITEADLNDVDKARAIAKKAGAKVLGHEGLGKLQVMIFEELVESKLEQPHFITEYPFEVSPLARRNDQNPAVTDRFELFIGGREIANAYSELNDAEDQAERFHAQVAEKDAGDDEAMHFDADFVRALEYGMPPTAGEGIGIDRLVMLLTNSPSIRDVILFPHMRPQA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4177_ARATH
Sequence: MEEYEFLVRVREAGGFDIEHLMDTKPSSCVIGCREFDNNDDYNAHIVLFARMGIHKYNMIQGTNLQLSCVEKYNYRSPRVYSAFYITLIAKDPDACNSLVTFQTRVVEEGFNMTKLSCNIARPKPGPQENAALPRHSVDLEPVDVFYKGSLPEWPPEDAFNDNI
What are the official names of this protein?
Uncharacterized protein At4g17700.
Protein: Y2748_PECAS
Sequence: MPQSSRYSDEHVEQLLSEMVNVLEKHHAPTDLALMVLGNMVTNLINTSIAPAQRQILARSFAEALQASIKKADKAH
What are the official names of this protein?
UPF0352 protein ECA2748.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: ARNA_WIGBR
Sequence: MKVIVFAYHEIGYIGLSCLIKLGFKVLSVITHIDDHASEKIFFSSVKKKSLKHKIPVFYPKNINNLKWIDYLSKLKPDIIFSFYYRKILSEDILKIPKLGSFNLHGSLLPKYRGCSPLNWVLINGEKTTGVTLHRMTKKIDHGSILSQYSIKIEEKDTSKSLYKKLCYASMYILNKTLPMILKNKINEIDCTDDFSSYFHKRYPKDGLIDWNQSANNIYNLIRALTKPWPGAFSYLFDKKIIIWKSKISFESYKTPGTILNFNPLIISCKKKSLEILSAQYTECNILNKRNIENISRIKGKKLIIKNIKSFKNLKKILILGVNGFIGYHITNLLLKYNNYKIYGIDIKNNLVKSFIGNEKFCFIKGDIKQYYNWVKKKIKKCDIILPLIAIARPMQYIKNPLKVFKIDFEENLKIIRYCVKYKKRIIFPSTSEVYGMCKDDYFDEENSNLVTGAIKNQRWIYSSSKQLLDRIIWAYGVKNNLNFTIFRPFNWIGPGLDDFKIAEKQNARVTTQIIFNLINGLPVTIVNNGNQKRCFTDIDDGIEALFEIIKNKNNKCNKKIINIGNPHNEYTIMQLTKIIINIIYSNNRNYNFPKFSGFNMLSGTNYYGEGYQDIDRRKPNIDIAKKLLNWTPKTKIRITLRKIINFFINNNTS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: RUVA_LACGA
Sequence: MFEYLKGIVAKIDPAYVVLDVNGIGYKILCPTPYSYQENQPATIYVEQVVRDTGITLYGFLSLEDKELFLKLLSVSGIGPKSAVAIMAAEDTDSLASAIQNGEVKYLTRFPGVGKKTASQIVLDLKGKLGDYVKKSAVATDLTPSLQDALLALVALGYTQKEVDRITPKLAKLPENTADGYIKEALALLLKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: EFTS_CYTH3
Sequence: MSTITAAEVNKLRTMTGAGMMDCKKALTESGGDFEAAIDILRKKGQKVSAARAENTTSEGIVSITVSADGKNGKLVALACETEPVSKVADFKNLSEAIMAVAVAKKPATTEELSALPLADGRTVQEHIIDLTGKIGEKVTITSYVSMDGEQVVPYIHSNGKLGVMVALKNTGGKDCSEAGRDVAMQAAAMKPVALDKDDVDPKTVEREIEIGKEQARAEGKPEAMLEKIALGKLNKFYKDATLLNQEFVKDNSKSISQMLDGFHKGLTVSAFVRISLS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_CUPPJ
Sequence: MSNALYQSSISSLPLLGHGKVRDNYAVGEDKLLIVTTDRLSAFDVIMGEPIPDKGRVLNQMANFWFRKLAHIVPNHETGVAAETVVAPAEVEQVKGRAVVVKRLKPILVEAVVRGYLAGSGWKDYQATGKVCGIELPAGLQNAQKLPEPIFTPAAKAEMGEHDENISFGEVEERIGIALARQMRDISIRLYKEAAEFAATRGIIIADTKFEFGLDENGTLTLMDEVLTADSSRFWPADSYQVGTNPPSFDKQFVRDWLEAVRIDGKPWPKTAPAPKLPDDVIEKTAAKYREALTRLTGEELQ
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MTNC_XANOR
Sequence: MTRPQAILTDIEGTTSSISFVKDVLFPYARRAMPAYVREHGNHPQVRHWLNQVADEIGEDVPDDVLITTLQTWIDEDRKHTALKALQGLIWGDGYKIADFTAHMYADAALQLQAWHAAGIPLYVYSSGSVPAQKLFFAHSDAGDLSGLVSDWFDTEVGSKREAASYRRIAERIGVPASEILFLSDVIEELDAAKRTGIRTALLERREDYPTPRSADDVGSHQRVESFSQLVF
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: DCUP_YERPE
Sequence: MNELKNDRYLRALLRQPVDMTPVWMMRQAGRYLPEYKATRAIAGDFMSLCKNAELACEVTMQPLRRYPLDAAILFSDILTIPDAMGLGLYFETGEGPRFQSPITCRADVEKLPIPDPEQELGYVMNAVRTIRRELAGSVPLIGFSGSPWTLATYMVEGGSSKAFTKLKKMMYAEPQTLHLLLDKLADSVILYLNAQIKAGAQSVMIFDTWGGVLTGRDYHEFSLNYMHKIVDGLIRENEGRRVPVTLFTKGGGPWLEAMAATGCDALGLDWTTDIADARRRVGDKVALQGNMDPSVLYAPPARIEQEVSTILASFGQGEGHVFNLGHGIHQDVPPAHAGAFVNAVHALSRPYHQK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_CMVCS
Sequence: MAFQGTSRTLTQQSSAATSDDLQKILFSPEAIKKMATECDLGRHHWMRADNAISVRPLVPEVTHSRIASFFKSGYDVGELCSKGYMSVPQVLCAVTRTVSTDAEGSLRIYLADLGDKELSPIDGQCVSLHNHDLPALVSFQPTYDCPMETVGNRKRCFAVVIERHGYIGYTGTTASVCSNWQARFSSKNNNYTHIAAGKTLVLPFNRLAEQTKPSAVARLLKSQLNNIESSQYLLTNAKINQNARSESEELNVESPPAAIGSSSASRSEAFRPQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: SYDND_BRUO2
Sequence: MHRYRSHTCAALRKTDVGSNVRLSGWVHRVRDHGGILFIDLRDHYGITQIVADPDSPAFKVAETVRGEWVIRVDGEVKARADDAVNTNLPTGEVEIFATEIEVLSPAKELPLPVFGEPDYPEDIRLKYRFLDLRRETLHKNIMSRTKIIAAMRRRMTEIGFNEFSTPILTASSPEGARDFLVPSRIHPGKFYALPQAPQQYKQLLMVAGFDRYFQIAPCFRDEDPRADRLPGEFYQLDLEMSFVTQEEVWETMEPVMRGIFEEFAEGKPVTKVFRRIAYDDAIRTYGSDKPDLRNPIEMQAVTDHFAGSGFKVFANMIANDAKVEVWAIPAKTGGSRAFCDRMNSWAQSEGQPGLGYIFWRKEGDKLEGAGPIAKNIGEERTEAIRKQMGLEDGDACFFVAGLPSKFYKFAGDARTRAGEELNLVDRDRFELAWIIDFPFYEWDEDNKKIDFAHNPFSMPQGGMDALENMDPLEIKAYQYDLVCNGFEIASGSIRNQLPEVMVKAFEKVGLSQQDVEERFGGLYRAFQYGAPPHGGMAAGIDRVIMLLVGAKNLREISLFPMNQQALDLLMGAPSEVSPAQLRDLHVRLAPVQKS
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_BARBK
Sequence: MADLAKIVEDLSNLTVLEAAELSKLLEEKWGVSAAAPVAVAAVGSAAAPAAEEKTEFDVVLVDGGAQKINVIKEVRALTGLGLKEAKDLVEGAPKPIKEGVSKDEAEKIKAQLEAAGAKIELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RS27A_ICTPU
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKIHRLRRECPADECGAGVFMASHFDRHYCGKCCLTYCFNKPEDK
What is the function of this protein?
Component of the 40S subunit of the ribosome.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a, Ubiquitin carboxyl extension protein 80.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: CTNL1_HUMAN
Sequence: MAASPGPAGVGGAGAVYGSGSSGFALDSGLEIKTRSVEQTLLPLVSQITTLINHKDNTKKSDKTLQAIQRVGQAVNLAVGRFVKVGEAIANENWDLKEEINIACIEAKQAGETIAALTDITNLNHLESDGQITIFTDKTGVIKAARLLLSSVTKVLLLADRVVIKQIITSRNKVLATMERLEKVNSFQEFVQIFSQFGNEMVEFAHLSGDRQNDLKDEKKKAKMAAARAVLEKCTMMLLTASKTCLRHPNCESAHKNKEGVFDRMKVALDKVIEIVTDCKPNGETDISSISIFTGIKEFKMNIEALRENLYFQSKENLSVTLEVILERMEDFTDSAYTSHEHRERILELSTQARMELQQLISVWIQAQSKKTKSIAEELELSILKISHSLNELKKELHSTATQLAADLLKYHADHVVLKALKLTGVEGNLEALAEYACKLSEQKEQLVETCRLLRHISGTEPLEITCIHAEETFQVTGQQIISAAETLTLHPSSKIAKENLDVFCEAWESQISDMSTLLREINDVFEGRRGEKYGYLSLPKPMKNNANLKSLKPDKPDSEEQAKIAKLGLKLGLLTSDADCEIEKWEDQENEIVQYGRNMSSMAYSLYLFTRGEGPLKTSQDLIHQLEVFAAEGLKLTSSVQAFSKQLKDDDKLMLLLEINKLIPLCHQLQTVTKTSLQNKVFLKVDKCITKTRSMMALLVQLLSLCYKLLKKLQMENNGWVSVTNKDTMDSKT
What is the function of this protein?
May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1).
What are the official names of this protein?
Alpha-catulin, Alpha-catenin-related protein, ACRP, Catenin alpha-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the vinculin/alpha-catenin family.
Protein: OLEO1_ARATH
Sequence: MADTARGTHHDIIGRDQYPMMGRDRDQYQMSGRGSDYSKSRQIAKAATAVTAGGSLLVLSSLTLVGTVIALTVATPLLVIFSPILVPALITVALLITGFLSSGGFGIAAITVFSWIYKYATGEHPQGSDKLDSARMKLGSKAQDLKDRAQYYGQQHTGGEHDRDRTRGGQHTT
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
What are the official names of this protein?
Oleosin 18.5 kDa.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Protein: MURD_ALISL
Sequence: MTGFGGVKNVVVVGLGMTGLSVVKHLLRQPEALIVKVIDTRETPPGQEQLPEQVELHSGSWQQDWLLDADLIVTNPGIALASSQLQPAIKKGTPVVGDIELFAWAVTAPVIAITGSNGKSTVTDLTGEMANAAGVKTAVGGNIGFAALDLLEQDADLYVLELSSFQLETTSSLKLKAAAFLNLSEDHMDRYQGMEDYRQAKLRVFDHADVCIVNRDDKETYPDTADKTLISFGFDTSDEYGCIEENGRLFLAKNNTPIIAANELGLVGKHNIANSLVALALLDAAGVNTNKTLDTLKRYNGLTHRCQVVAEMNGVRWVNDSKATNVASTLAALSGLSIEGKLHLLVGGVGKGADFSELSPALNELDLMMYCFGEDGVQFMPLDPRSRLCQTMDEAIELLSPELTFGDMVMLSPACASFDQYTNFMARGDAFTALAKHYSTEK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAD_PYRHO
Sequence: MSILLKGGLILYDTSYHPTRADILIEGDKIVEVKRNINKAADEVIDASHSLIIPAFINAHTHSPMVIFRGLAEDVPLMDWLQNYIWPAERKLKRKEVYWGAKLALLEMVHSGISTFVDMYFYMEEVARATLEVGLRGFLGYGMVDLEDEEKRRKEIKETEKLHEFITKLNSKLVKFILAPHAPYTCSLDCLKWVAEKSREWDSLVTIHLAETRDEIKIMEEKYGRSPVEVLKEANLLNDKLIAAHGIWLSKKDLEMLASSNVTIAHCPASNMKLGSGIFPMRDAIDEDINVALGTDGAASNNTLDIIREMRLASLLQKVNTLNPAIVKSEEIFRMATINGAKALKLKAGIIKEGYIADIAVINLKRSHLLPLHNPLATLIFSAKAGDIDTLIVSGRVIMLDGEVLTIDEEKVIDKFLGVGI
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: FRDC_ECOBW
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLJ_METC4
Sequence: MPSTPLSATVEALSEDAAQARHAELSRAIERANQLYYNEDAPELTDAEYDALRQELEAIEARFPALTGTTEASAGVGAKPSEKFAKVRHAVPMLSLGNAFADEDVDEFVARVRRFLNLPAEEAVAFTAEPKIDGLSLSLRYEAGRLVTAATRGDGEVGENVTANALTVDDIPETLSGEGIPEVLEVRGEIYLSHEDFAAINARQEAAGKPLFANPRNAAAGSLRQLDPAITASRPLRFFAYAWGEVSEPFTDTQSAVLERFRGWGLPVNPRTKLCRSAEEMIAHYRAIEAERAGLGYDIDGVVYKVDDLGFQRRLGFVSRAPRWALAHKFAAQEAITELLAIDINVGRTGSLNPLARLKPVTVGGVVVSNATLHNEGYVQGVGADGEPIREGRDIRVGDTVIVVRAGDVIPKVRDVVIEKRPADAVPYVFPDTCPACGSRAVRELNPRTKKLDAIRRCTGGLICPAQGVERLKHFVSRNGLDLEGFGQTYIEVLFEAGLVKQPADLFRLEFEPLKAAIVARREALSAQRRTEGEPAPKKPTKKKGEEEDKAIKNLLASLDARRTIPLNRFLFALGIPQIGESTAKALAKRFPDMPALMAALAAATREQAGRDWLELSALPRIGPGTRDRLFETLDPLPGEAMQDLSLGARLRGRLTPSQREAVLAHYGSEAEADAALERAASQRPGDAYRLFADDGEIGPVATDSLIQFFSEPHNDAAVRALLEEVGTEPLAATTSAAAFAGKTVVFTGSLEKMTRSEAKATAERLGAKVSGSVSAKTDLVVAGPGAGSKLKDAEKHGVKVVSEDDWLAMLAEA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: HIS6_MYCMM
Sequence: MYTDTGLAVRVIPCLDVDAGRVVKGVNFENLRDAGDPVELAAAYDAEGADELTFLDVTASSSGRATMLEVVRHTAEQVFIPLTVGGGVRTVADVDLLLRAGADKVSVNTAAIARPDLLADMATQFGSQCIVLSVDARKVPVGPAPTPSGWEVTTHGGRRGTGIDAVEWAARGADLGVGEILLNSMDADGTKAGFDLAMLRAVRAAVTVPVIASGGAGNVDHFAPAVAAGADAVLAASVFHFRELTIGQVKAAMAAEGITVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CISY_RHIME
Sequence: MSEKSATVTFGGKSADLPVRSGSIGPDVVDIGSLYKQTTMFTYDPGFTSTASCESKITYIDGDEGVLLHRGFPIEQLAEHGDFLEVCYLLLYGELPTKAQKADFDYRVTHHTMVHEQMSRFFTGFRRDAHPMAVMCGCVGALSAFYHDSTDITDPHQRMVASLRMIAKMPTIAAMAYKYHIGQPFVYPKNDLDYASNFLRMCFAVPCEEYVVNPVLARAMDRIFILHADHEQNASTSTVRLAGSSGANPFACIAAGIACLWGPAHGGANEAALNMLAEIGTVDRIPEYITKAKDKNDPFRLMGFGHRVYKNYDPRAKIMQKTTHEVLAELGHKDDPLLEVAMELERIALTDEYFIEKKLYPNIDFYSGITLKALGFPTTMFTVLFALARTVGWIAQWNEMIEDPEQRIGRPRQLYVGAPLRDYVPISKR
What are the official names of this protein?
Citrate synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
Protein: RL11_BDEBA
Sequence: MAKKVTGMIKLQIPAGKANPAPPVGPALGQHGVNIMEFCKQFNARTQALGDSIIPIIITVYQDRSFTFITKTPPVSSLIKKALKLESGSKQPQKDKVGKINNDQIKQIATTKLPDLNCLKVESAMSQVAGTAKSMGIDIA
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PURL_PROMS
Sequence: MINHENNDLFDLNEALKVENLTLNDYEEICKRLKRKPNRTELGMFGVMWSEHCCYRNSKPLLSKFPTKGKNVLVGPGENAGVIDVGNNQKLVFKIESHNHPSAIEPFQGAATGVGGILRDIFTMGARPIAVLNSLRFGNLDKSSNVDLLRGVVSGIAHYGNCVGVPTVGGEIDFDDSYSGNPLVNVMALGLLETEEIVCSGAKNVGSPVLYVGNTTGRDGVGGASFASSELTTTSLDDRPAVQVGDPFIEKSLIEACLDAFKTGDVIAAQDMGAAGLTCSSAEMAANGNLGISIDLDLVPSREDDMSSYQYLLSESQERMLFVVKEEKISDLIEKFNKWGLYASVIGEVIGTNEVIISHKGNIVAQIPTSALSDDTPVNFHNVINNPPDDLLNKWEWKENDLPEINEQKIFSLKENKKFSFSEIILKLLSNPSIASKRWIYKQYDSQVQANTVFTPGKSDAAVVRLREQNKKSKNKVFSGVAASVDCNSRWVALDPFRGSIAAVAESARNVSCVGAEPVAITNNLNFSSPENEIGYWQLSSSCNGIAEACKALETPVTGGNVSLYNESKNKDNLITPINPTPVIGMVGKIDNVEKAISSEWKNIEDQIWLIGSYKSDTTTAASSYLEYFHGEITGRPPKIDLSDEKFCQSFLRNAILNSLVVSSHDISDGGLAIALAESCILSARGATIELEKDLNRVDNLLFAEGGSRIIFSISKMKQNEWFNYLKQNQINFPSSVYVKKIGYVSSDTLKIKINEKNICNIRVEELTEKFNNSISDYF
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.