PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_PSEFS
Sequence: MDIKRTILIVALAIVSYVMVLKWNQDYGQAALPTQNVATNQAAPAIPDTPLGNNASASADVPSANGETSAPLETPVVTNKDLIHVKTDVLDLAIDPQGGDIAQLKLPLYPRRQDHPDVPFQLFDNGGERTYLAQSGLTGTNGPDARATGRPVYSTEQKTYQLADGQNQLNVDLKFSLDGVNYIKRFSFTRGLYDLKVTYLIDNESGKPWSGNLFAQLKRDASSDPSSSTATGTATYLGAALWTSNEPYKKVSMKDIDKGSLKETVQGGWVAWLQHYFVTAWIPNKGDANLVQTRKDSQGNYIIGFTGPALTVAPGAKAETSATLYAGPKSQAVLKELSPGLELTVDYGFLWFIAQPIFWLLQHIHSIVGNWGWSIIFLTMLIKGIFFPLSAASYKSMARMRAVAPKLAALKEQHGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLSLYWVLLESVEMRQAPFMLWITDLSIKDPFFILPIIMGATMFIQQRLNPTPPDPMQAKVMKMMPIIFTFFFLWFPAGLVLYWVVNNVLSISQQWYITRKIEAATAKAAA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: END8A_MYCBO
Sequence: MPEGHTLHRLARLHQRRFAGAPVSVSSPQGRFADSASALNGRVLRRASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQVRMRMVGAEFGTDLRGPTVCESIDDGEVADVVARLGPDPLRSDANPSSAWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGEPEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRAGEPCRVCGGVIRTALLEGRNVFWCPVCQT
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity).
What are the official names of this protein?
Endonuclease 8 1, DNA glycosylase/AP lyase Nei 1, DNA-(apurinic or apyrimidinic site) lyase Nei 1, Endonuclease VIII 1.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: AGR8_CYCAE
Sequence: MSEQQYTLPDLLQNWPWNRHLSPYYEEAKRESSAWVESFKPFDQDGQRAFDAYLLASLTYSHGSREFVRLGCDLMNFYFVYDEYTDVSDSAVADRLANIVIDAMRNPENSSQSGDHLLGKMTKHFWTRALAMAPAGSPCFEHFITTSETYLRAVTQEAEDRANKRVRKVDDYLRLRRDTCGARPTLALIEFGLNLPNEVVRHPSLVALTEAAVDLIILVNDMHSYVRELSCGHENHNLITAIMLEHRLNRQDAFHWLGSHCSRVVDQFLSDLDELPSWGEPTDSGVRDYINGLGQWVRGNDDWSTESKRYYGEDGETIRQERLVTTRSGESNYIKFGQVGVQDSVRIQPIEAN
What is the function of this protein?
Terpene cyclase that catalyzes the cyclization of farnesyl diphosphate (FPP) to various sesquiterpenes, including beta-elemene, gamma-muurolene, alpha-selinene, beta-selinene, beta-cadinene, delta-cadinene and alpha-cadinol.
What are the official names of this protein?
Sesquiterpene synthase Agr8, Terpene cyclase Agr8.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: LSRG_SALTY
Sequence: MHVTLVEINVHDDKVEQFIDVFRQNHLGSIKEPGNLRFDVLQDPQVLTRFYIYEAYVDEQAVAFHKTTPHYKTCVEQLEPLMTGPRTKKVFMGLMP
What is the function of this protein?
Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle.  Catalyzes the conversion of (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione (P-DPD) to 3-hydroxy-5-phosphonooxypentane-2,4-dione (P-HPD).
What are the official names of this protein?
(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase, Autoinducer 2-degrading protein LsrG, AI-2-degrading protein LsrG, Phospho-(S)-4,5-dihydroxy-2,3-pentanedione isomerase, Phospho-AI-2 isomerase.
What is the protein family that this protein belongs to?
Belongs to the LsrG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUT3_ORYSJ
Sequence: MAVDMELDGGGDGKGKAPPQISLSGLFLACMVAGGVQYGWALQLSLLTPYVQTLGIPHALTSVMWLCGPIAGLIVQPCVGLYSDKCTSSLGRRRPFILTGCIIICISVIVIGFSSDIGYALGDTTEDCKVYRGPRYHAAAAFILGFWLLDFSNNTVQGPARALMADLSGRHGPSAANAIFCSWMALGNILGYSSGSTNDWHKWFPFLMTRACCEACANLKAAFLVAVVFLGLSTAVTMVFAREVALDPVAAAKRNEGEASGLLAVFKGMKNLPVGMPSVLIVTGLTWLSWFPFILFDTDWMGREIYHGRPDGSPAEVTAFQEGVRQGAFGLLLNSIVLGISSFLIEPMCRRLGARAVWVMSSAVVCVAMAAVSVLSAWSLGDFGGSVQDAARAPAEEGGVRASALALFVFLGLPFAVLCSVPFAVTAQLAASRGGGQGLCTGVLNISIVVPQMAIALGAGPWDELFGEGNIPAFAMASVFAAAAAAAGVVLLPKVSVRSVSMAGGH
What is the function of this protein?
Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system).  May also transport other glucosides (By similarity).
What are the official names of this protein?
Sucrose transport protein SUT3, Sucrose permease 3, Sucrose transporter 3, OsSUT3, Sucrose-proton symporter 3.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CEP3_GAHVM
Sequence: MGQAVSYLTYTLRRCCKKNTLTTESGEVIELDDEHYDTVDLDDLRCSDPLMQPKFVLLKNGRRGKRNREYDNDHEKYVMMFNKE
What is the function of this protein?
Plays an important role in the cytoplasmic envelopment of tegument proteins and capsids during the assembly and egress processes.  Participates also in viral entry at the fusion step probably by regulating the core fusion machinery.
What are the official names of this protein?
Cytoplasmic envelopment protein 3.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 3 family.
What are the subcellular locations of this protein?
Virion tegument. Virion membrane; Lipid-anchor. Host cell membrane; Lipid-anchor; Cytoplasmic side. Host Golgi apparatus membrane; Lipid- anchor; Cytoplasmic side. Note=Virion membrane-associated tegument protein. Associates with host membrane lipids rafts. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: AZUP_PARPN
Sequence: MFHHSLAAAAAALLALAAPGFAATHEVHMLNKGESGAMVFEPAFVRAEPGDVINFVPTDKSHNVEAIKEILPEGVESFKSKINESYTLTVTEPGLYGVKCTPHFGMGMVGLVQVGDAPENLDAAKTAKMPKKARERMDAELAQVN
What is the function of this protein?
This soluble electron transfer copper protein is required for the inactivation of copper-containing nitrite reductase in the presence of oxygen.
What are the official names of this protein?
Pseudoazurin.
What are the subcellular locations of this protein?
Periplasm.
Protein: H2AZ_ASPFU
Sequence: MPGGKGKSVGGKAGAKDAAGKTQKSHSAKAGLQFPCGRVKRFLKNNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPRINRALLLKVEQKKKNKSDA
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and spt15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: MNHA2_STAAS
Sequence: MSLVYLLIAILVIMAMILLMSKRRALAKYAGYIALVAPVISSIYFLIQIPSVAKLQYLSTSIPWIKTLDINLDLRLDGLSLMFSLIISLIGIAVFFYATQYLSSRKDNLPRFYFYLTLFMFSMIGIVLSDNTILMYIFWELTSVSSFLLISYWYNNGDSQFGAMQSFMITVFGGLALLVGFIMLYIMTGTNNITEILGQADHIKNHGLFIPMIFMFLLGAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYVYIVTFVGLITMLFGSITALKQWDLKGILAYSTISQLGMIMAMVGIGGGYAQHQQDAIASIYVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSGMRQLFPKMNLVMTIAALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMIAIVFVGVIASVFTFTYALYMVKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVLALRAVSGGNHQIDQLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSKSYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMIIIGYGYIRIGLPKVHQLHVSEFGALEIILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLFFIAMKAPDLALTQLVVETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSSISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDERE
What are the official names of this protein?
Putative antiporter subunit mnhA2, Mrp complex subunit A2, Putative NADH-ubiquinone oxidoreductase subunit mnhA2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit A family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: C5AP_STRP3
Sequence: MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPATEQAVEVPQQTAVSEEAPSSSSKETNPPQTPDDAEETVADKANDLAPQAPAKTADIPATSKETIRDLNDPSHVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKSKARYQSKEDLEKAKKDHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADQQDKEMPVLSTNRFEPNKAYDYAYANRGTKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDNSKKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDKFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPTKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGDVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEAATSATFSAEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTNLLEGHSNKPEQDGSDQVPDKTPETKPEQDGSGQAPDKKPEAKPEQDGSGQAPDKKPETKPEKDSSGQTPGKTPQKGQPSRTLEKRSSKRALATKASARDQLPTTNDKDTNRLHLLKLVMTTFFFGLVAHIFKTKRQKETKK
What is the function of this protein?
This virulence factor of S. pyogenes specifically cleaves the human serum chemotaxin C5a at '68-Lys-|-Asp-69' bond near its C-terminus, destroying its ability to serve as a chemoattractant.
What are the official names of this protein?
C5a peptidase, SCP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: CYSD_VIBCM
Sequence: MDQQRLTHLKQLEAESIHIIREVAAEFDNPVMMYSIGKDSSVMLHLTRKAFYPGKIPFPLLHVDTDWKFRDMITFRDTTAKKYGFDLIVHKNPEGLAAGINPFDHGSSKHTDIMKTQGLKQALNKYGFDAAFGGARRDEEKSRAKERVYSFRDKNHTWDPKNQRPELWRTYNGQINKGESIRVFPLSNWTELDIWQYIYLENIEIVPLYLADVRPVVQRDGMLIMVDDDRMKLREGEQIEHKSVRFRTLGCYPLTGAIESQANTLTEIIEEMLVATSSERQGRAIDHDQSGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RL30_CALMQ
Sequence: MQSTQGIERSGEHGRVIVAAVRIRGLVDVSPEVNHTLNLLRLRRRFTCSVYVLSDSIKGMLKSVESWATWGELSRDTLIQLLRRRGRIVGDLPLTDEYLKKYGWGSVEELVDAYLKGEVKSLWCRRGEGPRMINGKASCIPGLKPFFRLHPPKGGFKGSIKKPYGAGGELGYRGLDINDLILRMI
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: WZZB_SHIDY
Sequence: MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIVTQPDVGQIAGYNNAMNVIYGQATPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVNQELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKDLRIRQIQEALQYANQAQVTKPQVQQTEDVTQDTLFLLGSEALESMIKHEATRPLVFSPSYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALRNYNAK
What is the function of this protein?
Confers a modal distribution of chain length on the O-antigen component of lipopolysaccharide (LPS).  Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules.
What are the official names of this protein?
Chain length determinant protein, Polysaccharide antigen chain regulator.
What is the protein family that this protein belongs to?
Belongs to the WzzB/Cld/Rol family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FGF4_BOVIN
Sequence: MAGPGTAAAALLPAVLLAVLAPWAGRGGAAPTAPNGTLEAELERRWESLVARSLLAGLPVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQVLPDGRIGGVHADTSDSLLELSPVERGVVSIFGVASRFFVAMSSRGRLYGSPFFTDECRFREILLPNNYNAYECDRHPGMFIALSKNGKAKKGNRVSPTMKVTHFLPRL
What is the function of this protein?
Plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation.  Required for normal limb and cardiac valve development during embryogenesis (By similarity).
What are the official names of this protein?
Fibroblast growth factor 4, FGF-4, Heparin secretory-transforming protein, HST, Heparin-binding growth factor 4, HBGF-4.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOC_ECO7I
Sequence: MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIKAGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HN_PIV5D
Sequence: MVAEDAPVRGTCRVLFRTTTLIFLCTLLALSISILYESLIIRKQIMSQAGSTGSNFRLGSITDLLNNILSVANQIIYNSAVALPLQLDTLESTLLTAIKSLQTSDKLEQNCSWGAALINDNRYINGINQFYFSIAEGRNLTLGPLLNIPSFIPTATTPEGCTRIPSFSLTKTHWCYTHNVILNGCQDHVSSNQFVSMGIIEPTSAGFPSFRTLKTLYLSDGVNRKSCSISTVPGGCMMYCFVSTQPERDDYLSTAPPEQRIIIMYYNDTIVERIINPPGVLDVWATLNPGTGSGVYYLGWVLFPTYGGVIKDTSLWNNQANKYFIPQMVAALCSQNQATQVQNAKSSYYSSWFGNRMIQSGILACPLQQDLTNECLILPFSNDQVLMGAEGRLYMYGDSVYYYQRSNSWWPMTMLYKVTITFTNGQPSAISAQNVPTQQVPRPGTGDCSATNRCPGFCLKGVYADAWLLTNPSSTSTFGSEATFTGSYLNAATQRINPTMYIANNTQIISSQQFGSSGQEAAYGHTTCFRDTGSVMVYCIYIIELSSSLLGQFQIVPFIRQVTLS
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: RAA1A_ARATH
Sequence: MAGYRADEEYDYLFKLVLIGDSGVGKSNLLSRFTKNEFNLESKSTIGVEFATKTTKVEGKVVKAQIWDTAGQERYRAITSAYYRGAVGALLIYDVTRHATFENAARWLRELRGHTDPNIVVMLIGNKCDLRHLVAVKTEEAKAFAERESLYFMETSALDATNVENAFTEVLTQIHKIVSKRSVDGGGESADLPGKGETINVKEDGSVLKRMGCCSN
What is the function of this protein?
Involved in auxin-mediated response.  May be involved in vesicle trafficking of components involved in polar auxin transport.  Binds GTP and GDP and possesses intrinsic GTPase activity.
What are the official names of this protein?
Ras-related protein RABA1a, AtRABA1a, Ras-related protein Ara-2, Ras-related protein Rab11E, AtRab11E.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Located in the plasma membrane and endocytic vesicles derived from the plasma membrane.
Protein: OTC_DESVH
Sequence: MPKHFTRIRDLGFEGAWKVLERAKEMKDTGYRGRTLEGKVATLIFEKASTRTRISFEVAVRHLGGTTIFMTPAESQLGRSEPLRDTARVISRYTDCMIVRTFGQAKIDELASFGSIPVVNALTDEGHPCQVMSDVLTMYERTPDLSQVRVAWIGDGNNMANSWIEAAMYFPFELFMAFPEGYEPDRQLLGLALEAGAKIFLTRDPHMAIDGAHYVNTDVWASMGQEEEQKRREAAFKGFCIDGALMGRAHPDAKFMHCLPAHRGEEVTDEVMESPASIVWDQAENRLHMQKAILEWVFTE
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_CHLPN
Sequence: MPFKCIFLTGGVVSSLGKGLTAASLALILERQRLNVAMLKLDPYLNVDPGTMNPFEHGEIYVTDDGVETDLDLGHYHRFSSAALSRHSSATSGQIYARVIKREREGDYLGSTVQVIPHITNEIIQVILDAAKEHSPDVLIVEIGGTIGDIESLPFLEAIRQFRYDHSEDCLNIHMTYVPYLQAADEVKSKPTQHSVQTLRGIGIIPDAILCRSEKPLTQEVKSKISLFCNVPNRAVFNVIDVKHTIYEMPLMLAQEKIANFIGEKLKLATVPENLDDWRVLVNQLSQDLPKVKIGVVGKYVQHRDAYKSIFEALTHAALRLGHAAEIIPIDAEDENLTMELSQCDACLVPGGFGVRGWEGKIAAAKFCREQGIPYFGICLGMQVLVVEYARNVLNLDQANSLEMDPNTPHPIVYVMEGQDPLVATGGTMRLGAYPCLLKPGSKAHKAYNESSLIQERHRHRYEVNPDYIQSLEDHGLRIVGTCPPQGLCEIIEVSDHPWMIGVQFHPEFVSKLISPHPLFIAFIEAALVYSKDASHV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: MEND_HAEI8
Sequence: MSVSVFNRCWSKVILETLVRQGVSHVCIAPGSRSTPLTLEAVRLQNAGSVTCHTHFDERGLGFFALGIAKATQSPVAIIVTSGTATANLYPAIIEARQTGVNLFVLTADRPPELWECGANQAILQQNMFGQYPVANVNLPKPNADYSAQWLISLLEQAAFQQKQQGGVVHINVPFTEPLYDATDEEVNSHSWLQPLQRWLIQNKSWINVEVQQNEVLMHENWDHWRTKRGVVVVGQLPAEQAMGINSWASAMGWVLLTDIQSGVVPTTPYEDIWLANQTVREKLLQADIVIQFGARFISKRINQFLQAFKGEFWLVEQSGKALDPYHHSLTRFNAKAHHWLRAHPPLRQKPWLLEPLALSKFCATFIEQQVGGNLTEASLALRLPTLLPYNGVLFLGNSLLVRLVDALTQLPESYPVYTNRGASGIDGLLATAAGIGIGSNKPVVAVIGDTSTLYDLNSFALFKNVTQPTLIFVINNNGGAIFDMLPVDEQVKDQFYRLPHNGDFSQIAAMFDLKYAHPYTWADLNSVVKQAYSRRKATLIEIKTNPSDGSSLYKRLIDQISHAVIGA
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: VATL_GOSHI
Sequence: MSSTFSGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAE
What is the function of this protein?
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase 16 kDa proteolipid subunit, V-ATPase 16 kDa proteolipid subunit, Vacuolar proton pump 16 kDa proteolipid subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: RL10_NATTJ
Sequence: MKKTRQEKERMVEELTEKLSQAESAVLVDYRGLDVAQMNELRRQLGDSNVDFKVVKNTLTSIAAENAGIDEINQYLEGPVGIAFGYDDPVVPAKILNDFSKENEELEFKAAILGESVVGEEKVKNLAKLPSREELLGKVAGTFQAPIAGFAGACQGIIRKFVYAVDAVRQEKEDAS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ISPD_SALPA
Sequence: MAATLLDVCAVVPAAGFGRRMQTECPKQYLSIGNKTILEHSVHALLAHPRVTRVVIAISPGDHRFAQLPLANHPQITVVDGGNERADSVLAGLQAVAKAQWVLVHDAARPCLHQDDLARLLAISENSRVGGILASPVRDTMKRGEPGKTAIAHTVERADLWHALTPQFFPRELLHDCLTRALNEGAIITDEASALEYCGFHPALVEGRADNIKVTRPEDLALAEFYLTRTIHQEKA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: FABP4_ICTTR
Sequence: MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIRSESTFKNTEISFKLGQEFDEVTADDRKVKSIITLDGGVLVQVQKWDGKSTTIKRKREDDKLVVECVMKGVTSTRVYERA
What is the function of this protein?
Lipid transport protein in adipocytes.  Binds both long chain fatty acids and retinoic acid.  Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).  FABPs are important elements related to the hibernating state in mammals (PubMed:11779641).
What are the official names of this protein?
Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Protein: POTA_CLOPS
Sequence: MKDNNIIELKGITKSYGKDTILDNLSLNIKKNEFLTLLGPSGCGKTTTLKIIAGFETADSGQVVFENNIINDIPPYERQLNTVFQKYALFPHMNVYENIAFGLKLKKIPKDIIDQKVKEMLKLVALEGYENRDIEALSGGQQQRVAIARALVNEPKVLLLDEPLGALDMKLRKEMQIELKKIQQKLGITFIFVTHDQEEALTMSDTIVVMNKGEIQQMGSPEDIYNEPANSFVAKFIGESNIVDGIMLDDFKVEFGGKIFDCVDKGFEKNEAIEVVIRPEDFEMVKYENGMLKGTVTSIIFKGVHYEIEVKNENHTWILHNTKHAEIGSKIGLSLDPESIHIMKKESDV
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.