PharMolix/UniProtQA huggingface dataset:
Protein: ACDH_MYCA1
Sequence: MAIVGSGNISTDLLYKLLRSDWLEPRWMVGIDPQSEGLARARKLGLETTHEGVDWLLAQPEKPDLVFEATSAYVHRDAAPKYEAAGIRAIDLTPAAVGPAVIPPANLRQHLDAPNVNMITCGGQATIPIVYAVSRVVEVPYAEIVASVASVSAGPGTRANIDEFTKTTSRGVETIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAQSIHDVVKEVQSYVPGYRLLNEPQFDDPSLNSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLSVAGGTR
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: RS3_AZOPC
Sequence: MGQKINPISNRLGIIRGWDSNWCGGDNYGDILYEDSKIRKYLNTRLAKASVSRIVIERTLKLVTVVVCTARPGVIIGKGGQEVDKLKEELKRITSKEVQINIFEIKKPELDAAIVASNIARQLEAKIAYRHVIKVAIAAAMRMGAEGIKVQISGRLNGVEIARSEMYKEGRIPLHTLRANIDYALSEALTKVGLLGVKVWICRGEVYSKQDFVVQFASQRGMNRYEGSGDKSVKRRKRNGIKKNE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: PRMC_STRR6
Sequence: MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQQEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVELILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADISQEALDLARENAKNQNLQIFLKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYRRIAEDATDYLKDSGKIYLEIGYKQGQCVPELFRKHLPEKRVRTLKDQFGQNRMVVVDDGQD
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: YCF2_OENEH
Sequence: MGNQRNRVNLNPFRFWVFELREILREIKNSRYPFNSVGSFIHIFVHQERFLKLLDPRIWSVLRSQGSTGVVLFLVAVLIYRINNRNMIERKNIYLTGLLPIPTNFAGPRNETLEESFLSSNINRLIVSLLHLPKGKRLSESCFLDPKESTRVLPITKWRNWIGKRRDSSQLKGSSDQSRDHFDSIGTEDSEYHTLINQREIQQRKERSSLLDPSFLQTERTEIESDRFSKGLSGSSSKSRLFTEGEKEMNNHLPPEEIEEFLGNPTRSILSFFSDEWSELHLGSNPTERSTVDQKLLKKEQEVSFAPFRRSETKEIVNLFKTMAYLQKTVSIHPISSDPGCDMVPKDELDSEERFQEMADLFTLSITEPDLVYHKGFAFSIDSSVLDQKQFLAEARDESKKKSLLVLPPVFYQENESFYRRIRKRGVQISCGNDLEDPKPKIVVFASNNIVEAVNQYRWIRNLIQIQYSTHGYIRNVLNRFFLMNRSDRNFEYGIQRDQIGNDTLNHRTFMKYTINQHLSNLKKSQKKGSDPLILISRTERSVNRDPNAYRYKWSKGSKNFQEHLEHFVSEQKSRFQVVFDRYRSIRNRYRSIRNRYRSRINQYSSDRSEVSDKKDNRYRSRINQYSSDRSEVSDQKNLAKFRSFVFSKLLLFLSNSLPFFFVSFGNTPPIQRSEIRVSELKGPNDRLCNQFLESIGLQLVYLKKLKPFLLDDHETSQKSKLLFNKKPEGMIDSFHTRNNRGKSLDSYFSMISHDQDNWLNPVKPFHRSSLISSFYKANRLRFLNNPHDFGFFCNKRFPFYVDIKNLDFTYGQFLNILFIRNTKFSLCGDKKKHAFLERDTISSIESQVSNLFKDFPQSGDERYNFYKYFHLAMRSDPLVRRAIYSIADISGTPLTEGQRVNFERTYCQPLSDMNLSDSEGKNLYQYLNFNSNMGLIYSEKCFSSEKRKKKKPEKRKEKKPEKRKEKKPEKRKEKKPEKRKEKKPEKRKEKKPEKRKEKKPEKRKEKKQSLYLKQWVEKVQMDRALQGERVSLILSNWNLFKTYVMPFSLTSTGYNLLKLMFLDTLGSYVMPLLRSSPKFVSICYAISDPCGISWRILQKKLCLLQWNWISAISNKCFHKLLLSEESIHRNNESPSMTDLRWPNLGAFLYSILFLLFVAGHLVFSHLLFLSQDFSELQRDFARAQSLMIPSYIVELRELLDMYPAPRSFKKLFLAAREKLVNYLRWGGGRKSFLIHLFELLNITPNPIDRIAFLKNTRHLSHTSKELYSLITELGDFSSLCSGQRYRYDQIIENVNGPCCLIDDKIESWISNCDAIEDKEREFLVPFCNFTRETRIDQILLSLTHSDHLSNNDSASQMSEEPGAFYLRHLVDIHKKGLMNYECNTSCLAERRIFLAHYQTITYSPCGDNRSHFPSHGKTFSLRLPLHPSRATLVIGSIGSGRSYLVKSLATNSYVPLITVVLNKFLKNWTPQGFDIHESGVYDEYGDDAEEANDYGASFFDFLDNDSDDYEDRDSDDYDEPGASDDYEDRDMEDFVDSEMTEWLTKTNVPLVYQLLDDEIDEFYITLQFELAKAMSPCILWIPNIHDLDAKESDYLSLGLLVNHLSRDCGRRSTKNEILVIASTHIPQKVDPSLIGPDGLSTCIKTRRLLVPQQQQCLFTLSYTRGFHLENKMFHTHTNEFESTILGPSVPDLVALTNEALSISITQKKSIIDTTTIRYALHRKTWDLEADRNLSPAKEHGTLFYQVGRAFAHTVLLRNCPIDPISIYIKKNLCEAGDSSLYKWYFELGTSMKKLTILLYLLTCSAGSIAQDLLSPPGPDEQNLITSYGLVENDSDLVHGLSDIVHGLLELEGALVGSSPTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEEEVEGTEDEEGEGTEEEVEGTEDEEGEGTEEEVEGTEDEEGEGTEEEVEGTEDEEGEGTEDEEGEGTEEEVEGTEEEVEGTEDEEGEGTEKDSSQFDNDRVTLLLRPKPRNPLDIQRLIYQHQKYESELEEDDDDDEDVFAPQKMLEDLFSELVWSPRIWHPWDFILDCEAEIPAEEIPEEEDPLPEEALETEVAVWGEEEEGEADDEEDERLEAQQEDELLEEEDEELKEEEDELHEEEEEEEEEEEEEEEDELHEEEEEEEEEDELQENDSEFFRSETQQPQARDGFSEEEGCFRISQFMWVPGDPLSFLYKDTPFVEVLSYPEEATEISKELLRLLNPKTKRDAPKRARQRWWTKKKQDKHYELVLDRQRWLITKSSLSKSNGFFRSNTPSESYQYLSNLFLSNRRLLDQITKTFFRKKWLFPDEMKIGFMEQ
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: TPIS_PROMM
Sequence: MRKPVIAGNWKMHMTCAQAREYTAMFLPLIEATPNDRHVVIAPPFTAISSMAESVGGTRLELSSQNVHWEDDGAYTAEVSPTMLLEHQVRYAIVGHSEPRKYFSESDEQINRRARSAQAHGLIPIVCVGESDEQRERGEAERVIRRQVEQGLEDTDPDKLVVAYEPIWAIGTGKTCEASEANRICGLIRRWVGASELIIQYGGSVKPGNIDELMAMSDIDGVLVGGASLDPESFARIANYQTS
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_BACLD
Sequence: MKIKSISGNTSVSLKRSIDAGTEEQRKAVRGIIEEVKKNGNAAVSAFTRQFDGADVAGFRVSEEEIKEAYSALEERDLEIIQAAIFNIKEYHERQLATSWFYHRKDGTMLGQKITPLDSAGVYVPGGTAAYPSSVLMNVIPALVAGVDRIVLASPPGKDGKLSAGVLAAAAELGVTEIYKMGGAQAIAALAYGTETITPVDKITGPGNIYVALAKREVFGQVDIDMIAGPSEIAILADSTANYREIAADLLSQAEHDAMASSILVTDSETLAESVLKEVYRQLEHLPRKEIARQSIDNYGLIYVTETMNEAVSVINELAPEHLEILTVQPDALLGQIKHAGAIFLGRYSSEPVGDYFAGPNHVLPTNGTARFSSPLNVTDFQKRSSIISYSREAFRANAEKIAAFARLEGLEAHARAIESRNREED
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: GLMM_STAS1
Sequence: MAKYFGTDGVRGVANKELTPELAFKLGRYGGYVLAHNEGEKHPKVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGVISTPGVAYLTREMEADLGVMISASHNPVPDNGIKFFGSDGFKLSDDQEQEIEHLLDQDNPDLPRPVGEDIVHYSDYFEGAQKYISYLKSTVDVDLAGMKIALDGAHGSTSSLAPFLFGDLEADTVTIGCNPNGYNINQEVGSTHPESLAKVVVESECDFGLAFDGDGDRLIAIDEKGNIVDGDQIMFIIGQAMSKNQELNNNMIVSTVMSNLGFYKALENEGIQSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVLMDYNTTGDGLLTGVQLASIIKMTGKSLSQLTSQMKKYPQSLVNVRVTDKYRVEENIDVQEIMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAQRYANTIAEVVQDKMGLDN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: MNMA_FRATT
Sequence: MENKKVIVGISGGVDSSVSALLLKQQGYDVTGVFMKNWEEDDTDEFCSAEQDIADAQAVCDSIGIPFKKINFAAEYWDNVFEHFLIEYKAGRTPNPDILCNKEIKFKAFLSYVHLLGGDYIATGHYAQTRLAADGSVQLVKGLDDNKDQTYFLYTLGQEQLRQTIFPIGNIEKSKVREIAKENNLVTFDKKDSTGICFIGERKFKEFLSKYLPAQKGEIHDENGIKIGMHDGLMYYTIGQRQGLGIGGVKDRPEVPWFAAKKDLENNVLIAVQGHDHPLLFKQSLQAIELSWVAGMAPADKFRCAAKVRYRQKDQSCEVEVNQDGSVNVTFDQPQRAITPGQSVVFYIDDVCLGGGVII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F26L_CHICK
Sequence: MAAVASGQLTQNPLQKVWVPLSLHRLRRRGSTVPQFTNCPTMVILVGLRRPGKTYISRKLTRYLNWIGMPTRVFNVGQYRREAVQSYKNYEFFRHDNEEAMQIRRQCALAALQDVRTYLSSEEGQVAVFDATNTTRERRALIMQFARENGYKVLFVESICDDPAIIEENIKQVKLSSPDYKGCTPEEAVADFLQRIECYKATYEPLDEQLDSGLSYIKIFDVGVRYLANRVQGHVQSRTVYYLMNTHVTPRAIYLSRHGESQLNLKGRIGGDAGLSTRGRQYAQALAEFIRSQSIRELKVWTSHMKRTIETAEALGVPYEQWKALNEIDAGVCEEMTYEEIQERYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSEELPYLRCPLHTVLKLTPVAYGCEVESIFLNVEAVNTHRERPQNVDISRPPAEALVTVPEHY
What is the function of this protein?
Synthesis and degradation of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase, 6PF-2-K/Fru-2,6-P2ase, PFK/FBPase, 6PF-2-K/Fru-2,6-P2ase liver isozyme.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Protein: DNAK_BEUC1
Sequence: MARAVGIDLGTTNSVVAVLEGGEPTVIANAEGSRTTPSVVAFSKSGEVLVGEVAKRQAVTNVDRTITSVKRHMGTDWKVSVDDKSYTAQEISARVLGKLKKDAESYLGEPVTDAVITVPAYFNDAERQATKDAGQIAGLNVLRIVNEPTAAALAYGLERGKEDELILVFDLGGGTFDVSLLEVGKDEDDFSTIQVRATNGDNRLGGDDWDQRIVDWLVSQVKNKDGVDLSKDKIALQRLREAAETAKKELSSATSTTISLQYLSMSENGPIHLDEKLTRAQFQQMTEDLLERTKTPFHNVIKDAGISLSAIDHVVLVGGSTRMPAVTDVVKELTGGKEPNKGVNPDEVVAVGAALQAGVIQGERKDVLLIDVTPLSLGIETKGGVMTKLIERNTAIPTKRSEVFSTAEDNQPSVLIQVFQGERDFASDNKALGTFELTGIAPAPRGMPQIEVTFDIDANGIVHVSAKDRGTGKEQSMTITGGSALPKDEIDRMIKEAEAHAAEDHKRREEAEVRNTAEQLVYSTEKLLTENAEKLPEDVASEVRAAVAELKTALEGTDIDAVKAKQEALATASQKIGQALYASAEQEQAAGNPGAAEADAEAAAGAGTPEGADDDVIDAEIVDEDEKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SUB4_TRIRU
Sequence: MVCLKTLSVFLAAFAAADARAVFKTQGHKNSEMIPDNYIVVMKDGVSQDDFKAHISSVSSIHSTNKAKRGTNTEGMKREFDIMNWRGYHGHFDRDTLEEILNDSKVDYVEQDQVVRISGLVTQRSAPSWGLGRVSHRQAGSRDYVFDDSAGRGVTIYGVDTGIDINHQDFRGRARWGTNTADRDNADRHGHGTHTASTFAGTAYGIAKNANIVAVKVLGSDGSGSTSGIIAGINYCVQDAQQRGILGKAAMNLSLGGGFSQANNDAVTRAQNAGIFVAVAAGNDNKDARNYSPASAPAVCTVASSTINDSKSSFSNWGPVVDIYAPGSDIIAARPGGGSTTMSGTSMASPHVAGMGAYMIGMGANPRQVCDRLKQLATAAIRNPGFSTTNRLLYNGSGQ
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DX39A_HUMAN
Sequence: MAEQDVENDLLDYDEEEEPQAPQESTPAPPKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSEKNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQDRFEVNVAELPEEIDISTYIEQSR
What is the function of this protein?
Involved in pre-mRNA splicing.  Required for the export of mRNA out of the nucleus.
What are the official names of this protein?
ATP-dependent RNA helicase DDX39A, DEAD box protein 39, Nuclear RNA helicase URH49.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DECD subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Can translocate to the cytoplasm in the presence of MX1.
Protein: RLMKL_SHESR
Sequence: MLNFFAAAPKGFEYSLAQELTEFGATEIKESVAGVYFTAPLALAYRITLWTRLASRIVLVIYKGPCESAEQLYNAAYCIDWSAHFSNRNTFSIDFHGTGGFINNTQFGALKIKDAIVDRFRDDGDARPNVARIDADIKIDAHFRNGVITIAMNFSGPSLHQRGYRSTTGEAPLKENLAANMLVRSGWKAAPTTLLDPFCGSGTVLIEAALMAADIAPGLQRSRFGFEHWRRHDKATWHEILEEAKARASLGVKRCDVKFYGSDIDSRLVALAKRNAQNAGVLELIDFKVANALNVEPPAGEGYLITNPPYGERLGSVSELLQLYYQLGDKFKKEFGGWKVAMLCSDIELISALKLKADKQMKMFNGALECAFNLYTLHAQSTRRDTPVLPEGVDIADIAPAFANRIKKNAKQLEKWAKKEGIDSYRLYDADIPEYNVAVDRYLDHIVVQEYMAPASIPEAVTKRRLSDVLLALPAAIGVDPHKITMKTRERQKGTNQYQKLDERKLELITTEYGAKFKLNLTGYLDTGLFLDHRLTRRLVGQKSKGRRVLNLFSYTGSASVHAALGGAKSVTTVDMSNTYLAWAKENFALNDLSGKQYEFVQADCLQWIRDSALDKSAQYDLIFIDPPTFSNSKRMEDSFDVQRDHVNLLGMLIKLLSPNGEIVFSNNKRKFKMDTETLAKMKIKVENIDDLTLPMDYKRNPHIHNTWLITHA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_MARSD
Sequence: MRLSRYYIPTLKEDPSEAEVVSHKLLMRAGMIRKLTSGIYNYLPLGLKSVNKVAAIVREEMNRAGALEVLMPMVQPGDLWQETGRWDYYGKELLRVKDRHGRDYCLGPTHEEVITDLVRGEVKSYKQLPLNLYQIQTKFRDEIRPRFGLMRGREFIMKDAYSFDKDEAGAEESYRGMFEAYKKAFSRIGLNFRPVQADSGAIGGDFSHEFHVLADTGEDTIAVCKDEKCGYAANLEKAKVAAPTGESMLNAECPAIEEVATPGKHTVEEVCEFLGVEQDKLVKTLLFTVDGEPVAALVRGDRELNDVKLRNLVGGNEIEMASEEQVKEWTGAPVGFAGPVGLKIERIFADHELLTETDWIAGANKGDTHIKHLSLGRDCKIEQFADLRVITEADPCPECGAAIEFTKGIEVGHVFKLGSKYSKSMEATFLDENGKTQPMVMGCYGIGVSRIVASAIEQNNDENGAIFPPTIAPFELCVISLGGKDEAVNEKAEEFYNELMEMGIDAAYDDRKERPGVKFADADLIGYPMQLVIGGKGLKNGIVEAKNRKTGEKIELPLEGFTEAFKAWRAEIWQSWGLKA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_PHOLL
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTEVKIKGFAGEDATPALEGANVVLISAGVARKPGMDRSDLFNINAGIVRNLVEQVAKTCPKSLIGIITNPVNTTVAIAAEVLKKAGVYDKNRLFGVTTLDVIRSNTFVAELKGKKPQEIEVPVIGGHSGVTILPLLSQIPGVNFTDGELAALTKRIQNAGTEVVEAKAGGGSATLSMGQAAARLGLSLVRGLQGESDVVECAYVEGDGKYARFFAQPVRLGKNGVEERLNIGELSDFEQKALEGMLDVLRKDIELGEKFINN
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: CH60_ECO55
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_SALPC
Sequence: MATYLIGDVHGCYDELIALLQQVEFTPDTDTLWLTGDLVARGPGSLDVLRYVKSLGNSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWLRRQPLLLVDEEKKLIMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMPNNWSPELSGLARLRFITNAFTRMRYCFPNGQLDMYSKASPENAPAPLKPWFAIPGPVSEAYSIAFGHWASLEGKGTPEGIYALDTGCCWGGELTCLRWEDKQYFVQPSNRQMDMGEGEAVNA
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: BETI_PECCP
Sequence: MPKVGMQPIRRQQLIEATLAAINDVGMHDASIVQIARRAGVSNGIISHYFRDKNGLLEATMRYLISHLGLAVKSRLLSLTENTPRARLRAIVQGNFDDSQTNSAAMKTWLAFWASSLHSPMLHRLQQVNDRRLYSNLCIEFSHCLPKDNARIAAKGLAGLIDGLWLRSALSHDAFNREEALSIAYDYIEQQLTRT
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: GMSS_CLOCO
Sequence: MEKKTIVLGVIGSDCHAVGNKILDHAFTNAGFNVVNIGVLSPQEVFIKAAIETKADAILLSSLYGQGEIDCKGLRQKCDEAGLEGILLYVGGNIVVGKQHWPDVEKRFKDMGYDRVYAPGTPPEVGIADLKKDLNIE
What is the function of this protein?
Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).
What are the official names of this protein?
Glutamate mutase sigma subunit, Glutamate mutase S chain, Glutamate mutase small subunit, Methylaspartate mutase.
What is the protein family that this protein belongs to?
Belongs to the methylaspartate mutase GlmS subunit family.
Protein: YPY1_HALHA
Sequence: LQFTAALAQRLTAEGAELWLDTTARRLLGGPAGVEGVETSRGIIDADAVVVAAGSYSPALTRRFGLRLPIEPVKGYSVSIPLHGIEGAPGMSIIDDARKVVVTRLGEQLRIAGKAEITGFDLRLDERRWRAVREQGLSRFPRLAEQLADAPSQPWAGLRPMTCDGPPILGPTPISGLHLATGVGHLGWTFAAGSARLVADQLEERTCDLDPAPYSLQRYG
What are the official names of this protein?
Uncharacterized oxidoreductase in pyp 5'region, ORF1.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: WLS_MOUSE
Sequence: MAGAIIENMSTKKLCIVGGILLVFQIVAFLVGGLIAPAPTTAVPYTAIKCVDVRKNHHKTRWLAPWGPNKCDKIRDIEEAIPREIEANDIVFSVHIPLPSMEMSPWFQFMLFILQLDIAFKLNNQIRENAEISMDVSLGYRDDMFSEWTEMAHERVPRKLKCTFTSPKTPEHEGRYYNCDVLPFMEIGSVAHKYYLLNIRLPVNEKKKINVGIGEIKDIRLVGIHQNGGFTKVWFAMKTFLTPSIFIIMVWYWRRITMMSRPPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQHERNHIAGYWKQVGPIAVGSFCLFIFDMCERGVQLTNPFYSIWTTDVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKVRRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVSEGHWKWGGVTVQVSSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVHSGEELQLTTTITHVDGPTEIYKLTRKEAQE
What is the function of this protein?
Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism.  This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins.  Also plays an important role in establishment of the anterior-posterior body axis formation during development.
What are the official names of this protein?
Protein wntless homolog, Integral membrane protein GPR177, Protein evenness interrupted homolog, EVI.
What is the protein family that this protein belongs to?
Belongs to the wntless family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein.
Protein: G6PI_SHEB9
Sequence: MTLLTQSSTWQALSAHSKNVPHMRELFATDAARFNKMSLSACGLLLDYSKNRATAETLDLLFTLASNSQLEAKIKAMFAGEIINTTEKRAVLHTALRSTAEQSIIAEGQDIVPEVQQTLNKMQGFVSSVTSGQWKGYTGKAITDIVSIGIGGSFLGPKIVSQALRPYWNPELKCHFVANVDGTSISEKLKLLDPETTLFIMSSKSFGTQETLTNTLTAREWFLAKGGLQSDVAKHFVAVTSNVAKATDFGIDADNIFPMWDWVGGRYSLWSAIGLPIALLIGMDNFRALLSGAHQMDEHFANAPLTENMPVIMGLLSLWYGNFFNAQSHVVLTYDHYLRGLPAYFQQLDMESNGKSVTLNGTDVDYSTGPVIWGGEGTNGQHAYHQLLHQGTALIPADFIMPLQSHNPIGEHHDQLASNCFGQTQALMQGRTFDEALAELANSALPAAEKQLIAKHKVMPGNKPSNTLLMDKLTPSTLGALIALYEHRTFVQGAIWDINSFDQWGVELGKDLGNDVLTRIGASQDCDALDASSNALINLYRHGKI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRGC1_BOVIN
Sequence: MAWDMCNQDSVWSDIECAALVGEDQPLCPDLPELDLSELDVNDLDTDSFLGGLKWCSDQSEIISNQYNNEPSNIFEKIDEENEANLLAVLTETLDSLPVDEDGLPSFDALTDGDVTTENEASPSSMPDGTPPPQEAEEPSLLKKLLLAPANTQLSYNECSGLSTQNHANHNHRIRTNPAVVKTENSWSNKAKSICQQQKPQRRPCSELLKYLTTNDDPPHTKPTENRNSSRDKCTSKKKAHTQSQTQHLQAKPTTLSLPLTPESPNDPKGSPFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNPFRASPKLKPSCKTVVPPPSKKARYSESSCTQGSNSTKKGPEQSELYAQLSKTSVLTSGHEERKAKRPSLRLFGDHDYCQSINSKTEILVSTSQELHDSRQLENKDAPSSNGPGQIHSSTDSDPCYLRETAEVSRQVSPGSTRKQLQDQEIRAELNKHFGHPSQAVFDDKADKTSELRDSDFSNEQFSKLPMFINSGLAMDGLFDDSEDESDKLNSPWDGTQSYSLFDVSPSCSSFNSPCRDSVSPPKSLFSQRPQRMRSRSRSFSRHRSCSRSPYSRSRSRSPGSRSSSRSCYYYESGHCRHRTHRNSPLCASRSRSPHSRRPRYDSYEEYQHERLKREEYRREYEKRESERAKQRERQRQKAIEERRVIYVGKIRPDTTRTELRDRFEVFGEIEECTVNLRDDGDSYGFITYRYTCDAFAALENGYTLRRSNETDFELYFCGRKQFFKSNYADLDSNSDDFDPACIKSKYDSLDFDSLLKEAQRSLRR
What is the function of this protein?
Transcriptional coactivator for steroid receptors and nuclear receptors.  Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter.  Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis.  Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.  Acts as a key regulator of gluconeogenesis: stimulates hepatic gluconeogenesis by increasing the expression of gluconeogenic enzymes, and acting together with FOXO1 to promote the fasting gluconeogenic program (By similarity).  Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.  Also involved in the integration of the circadian rhythms and energy metabolism.  Required for oscillatory expression of clock genes, such as BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK (By similarity).
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, PGC-1-alpha, PPAR-gamma coactivator 1-alpha, PPARGC-1-alpha.
What are the subcellular locations of this protein?
Nucleus. Nucleus, PML body.
Protein: NADM_PYRFU
Sequence: MKRGLFVGRFQPVHKGHIKALEFVFDQVDEVIIGIGSAQASHTLKNPFTTGERMEMLIRALDESGLSKKKRYYLIPLPDINFNAIWVPYVESMVPKFEVVFTGNSLVAQLFRERGYKVVVQPMFKKDILSATEIRRRMIEGEPWEDLVPKSVAEYIKEIRGVERIRMLATNLESSEKELQAPIRIPEY
What are the official names of this protein?
Nicotinamide-nucleotide adenylyltransferase, NAD(+) diphosphorylase, NAD(+) pyrophosphorylase, NMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal NMN adenylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F210A_MOUSE
Sequence: MQWNVPRTMSRLALRTFVEAQKARLFDHHWRIKGPLLVHRGEYRVAWTPHLRKQWLHLSAVQCLAKQRNLLDAQPPQLGTLRQERWEQDILSKRVLSSSSTSQETPSEKKEETDPLQDKSISLYQRFKKTFRQYGKVLIPVHLITSGIWFGTFYYATIKGVNVIPFLEVIGLPDSIVDILKNSQSGNALTAYAMFKIATPARYTVTLGGTSFTVKYLRSHGYMSTPPPVKEYLQGRMEETKELITEKMEETKDRLTEKLQETKGKVSFKKKVE
What is the function of this protein?
May play a role in the structure and strength of both muscle and bone.
What are the official names of this protein?
Protein FAM210A.
What is the protein family that this protein belongs to?
Belongs to the FAM210 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Mitochondrion. Cytoplasm.