PharMolix/UniProtQA huggingface dataset:
Protein: UPS2_YEAST
Sequence: MKLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELKDQGKVLVTERLITVKQGVPKWIMMMLGGTNMSHVREVSVVDLNKKSLTMRSCNLTMCNLLKVYETVTYSPHPDDSANKTLFQQEAQITAYGSIRKLCNKMEDWSVQRFCENAKKGKMGFDAVLQVFSENWEKHVDDLSNQLVSKVNETMEDVKISAGTLLKGTERSGRTILQQNIDLFRDAYNHEN
What is the function of this protein?
Required for mitochondrial cristae morphogenesis and MGM1-processing.  Controls the stability of mitochondrial phosphatidylethanolamine (PE).  With UPS1, controls the level of cardiolipin in mitochondria.  Cardiolipin is a unique phospholipid with four fatty acid chains and is present mainly in the mitochondrial inner membrane where it stabilizes the electron transport chain supercomplex between complexes III and IV through direct interaction of their subunits.
What are the official names of this protein?
Protein UPS2, mitochondrial, Altered inheritance rate of mitochondrion protein 30, Genetic interactor of prohibitins protein 1, Unprocessed MGM1 protein 2.
What is the protein family that this protein belongs to?
Belongs to the slowmo family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Mitochondrion intermembrane space. Note=Lacks the two major intermembrane space-targeting signals, bipartite presequences and cysteine motifs, and import is mediated by another IMS protein, MDM35.
Protein: AIF1_PIG
Sequence: SETIDLQGGKAFGLLKAQQEGRLNEINKQFLDDPKYSSDEDLSRKLEAFKQKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIKEVSSGSGETFSYSIFLKMMLGKRSAILKMILMYEEKAREQEKPTGPPAKKAISELP
What is the function of this protein?
Actin-binding protein that enhances membrane ruffling and RAC activation.  Enhances the actin-bundling activity of LCP1.  Binds calcium.  Plays a role in RAC signaling and in phagocytosis.  May play a role in macrophage activation and function.  Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes.  Enhances lymphocyte migration.  Plays a role in vascular inflammation (By similarity).  Has a dual influence on glucose-induced insulin secretion: inhibition at low concentration and stimulation at high concentrations.
What are the official names of this protein?
Allograft inflammatory factor 1, AIF-1, Daintain.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, phagocytic cup. Note=Associated with the actin cytoskeleton at membrane ruffles and at sites of phagocytosis.
Protein: Y3436_AROAE
Sequence: MIFVISPAKALDFETPPVTAAATQPDYLREAEELIGILRQKTPAEVAELMHLSDPLAALNVARYERWHRPFTPDNAKQALLAFNGDVYGGLDAPSLSEDDFAWAQQHLRILSGLYGMLRPLDLMQPYRLEMGTRLGNPRGANLYAYWGDTLAEALNRLLAAERDAGGSAVLVNLASQEYFKAAARAKLTAQVITPVFEDWKGGRYRIITFYAKRARGLMSRYAIRNRVEDVEGLKGFDAEGYGFAPDVSDAETLVFRRRAD
What are the official names of this protein?
UPF0246 protein AZOSEA34360.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: ZAPC_EDWI9
Sequence: MNIKPGDRWCWFFDRQHDRLMLDLANGMVFRSRFPSKMLTPDAFDASSFCVDDAASYYHFAERCQASGLDTAQCAELVLNALVAQRFLKPIMPKSWYFTPQPGRYVPEMGELVGVQLLDTPDWGRLLVIAPGASASLCLLAQPSLALAGKRLMLGEAIKVMHDRLLPLSTHPETLSDDTTLACAG
What is the function of this protein?
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ.  Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
What are the official names of this protein?
Cell division protein ZapC.
What is the protein family that this protein belongs to?
Belongs to the ZapC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_SYNWW
Sequence: MALSPEEVNHVAMLARLALSEDEKTAFAEQLTLILDYVERLNELDTGEVEPLIHILPVFNVLRQDEALPGSSQEEILSNAPLVEDGQYKVPRII
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: FOLD_POLNA
Sequence: MTAQLIDGNALSRQLRTEVAQRAALLRARGITPGLAVVLVGDNPASQVYVRNKVKACEDNGLHSVLERYPAEMSEADLLARVEALNNDPAIHGILVQLPLPAHIDAQKVIEAISPAKDVDGFHVGSAGALMVGQPGFWPCTPYGCMKMLESIGYDLRGKHAVVIGRSNIVGKPMALMLLQKNATVTICHSATADLKAMTLQADVIVAAVGKRNVLRADMVKPGAVVIDVGMNRNEEGKLCGDVDFDGVKEVAGYITPVPGGVGPMTITMLLVNTLEAAERG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MPS1_ARATH
Sequence: MDREDNLPVQPDKPPKSLVRPILNLETTSSSSSSSSSSPELLRHLQAAFKRHRPLSKMQTTSIGPRRSVAPQRQASRNTRLVTAEGQRSQDVVTLSQSLAANTLTQDTTNNLAITSVAGESASITQPTVSEHFNPSDRQMDFGKSAVTSLESNLDVQRKSQSLIGTSQDMEWDATNQAEASHLDACIGSKHQNLPSVDSEVSLKSEYKDSSSLAKIQGQLGEFPNFLNQPRTRCSAVGSSWATTTLIHSSSAPMLNATTHVSRSYVEADSNANPHAVQSQGNLPSCCPSSKVSNILHPNKDATASEMPASTNDPEVRVKETDTSKQQQITTGLEAPVGSSIYGSDGQANARLPEELHTSVSSQPQKSDKHEKVASSKGPSAPRKRNYDPDLFFKVNGKLYQRLGKIGSGGSSEVHKVISSDCTIYALKKIKLKGRDYATAYGFCQEIGYLKKLKGKTNIIQLIDYEVTDKTLLQEVLNGTMSNKDGRVKEDGFIYMVLEYGEIDLAHMLSQKWREIEGSDRTIDENWLRFYWQQILQAVNTIHEERIVHSDLKPANFLLVRGFLKLIDFGIAKAINSDTTNIQRDSQVGTLSYMSPEAFMCNESDENGNTIKCGRPSDIWSLGCILYQMVYGRTPFADYKTFWAKFKVITDPNHEITYNQLSNPWLIDLMKKCLAWDRNQRWRIPELLQHPFLAPPIPHEPQVKTIKLFSLIAESCGSDDDKANSMISQLEQLLSNPAPLPRNDVLDSRDQNQQLLSRVSELCIQLQDRLQGLEGEN
What is the function of this protein?
Involved in the regulation of the onset of mitosis.  Involved in a pathway that coordinates cell proliferation and differentiation.  Implicated in spindle pole body (SPD) duplication (By similarity).  May be a downstream regulator of auxin signaling in the formation of secondary roots (Probable).
What are the official names of this protein?
Serine/threonine-protein kinase MPS1, Monopolar spindle protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: PTPA_STAEQ
Sequence: MIHVAFVCLGNICRSPMAEAIMRQRLQERGISDIKVHSRGTGRWNLGEPPHNGTQKILQKYHIPYDGMVSELFEPDDDFDYIIAMDQSNVDNIKQINPNLQGQLFKLLEFSNMEESDVPDPYYTNNFEGVFEMVQSSCDNLIDYIVKDANLKER
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpA, Phosphotyrosine phosphatase A, PTPase A.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: RL15_STRPI
Sequence: MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIVKAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: AKCL2_PIG
Sequence: MEKIPVLGLGTWQAAPGEVTEAVKVAIDTGYRHFDCAYLYHNENEVGVGIQAKIDEGVVRREDLFIVSKLWCTCHKKSLVKSACTRSLKALKLQYLDLYLIHWPMGFKPGEVDLPVDRSGMIVASNTDFLDTWEAMEDLVIEGLVRAIGVSNFNHEQLERLLNKPNLRVKPVTNQIECHPYLTQKKLISFCQSRNVSVTAYRPLGGSSEGVPLLEDPVIQTIAQKHGKSAAQILIRFQIQRNVIVIPKSVNPKRILENFQVFDFELSEQDMTDLLGLDRNLRLSAFPIAENHKDYPFKAEY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol.
What are the official names of this protein?
1,5-anhydro-D-fructose reductase, AF reductase, Aldo-keto reductase family 1 member C-like protein 2, Aldo-keto reductase family 1 member CL2, Aldo-keto reductase family 1 member E2.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: RT109_PNECA
Sequence: MDNLYTGISKSIESLPPEITFSYGYIFTNFKKLKWPWLNKRKIDNVYLSNHFFFILQEDAMAYAIEVLIFFSSELSVFYISKADSTGFFNRHGSPSPLKAVISTFLSYLIRRFSRKNIPSRISLFSRSQPQYLFPSSSLNPSKHILDDRELVRWWLKVLDSVNGSQCPKKYVLIPGMDPRETLKYTPQHVDTDLNWICGHPYESMGQSAGEIIPRFPDDPKTRFLDQLDRDGEVVSIDKFWELMAFRQECIHGRIVGFFSLEFPGNDQDGTNNTITEDLDLQNGIQINEKIYRMVYEKLLRSDFETLEKSKGATLDLINDINNSKDIKDSVDWIKKVSGKKTSEDKKRKAIDISEQLKPVNILNESLIRKKSKKK
What is the function of this protein?
Histone chaperone-dependent acetylase that modifies 'Lys-56' of histone H3 (H3K56ac) (PubMed:20656950).  Histone H3 'Lys-56' acetylation may be required for S-phase-linked DNA damage tolerance (By similarity).  Also acetylates 'Lys-9' of histone H3 (H3K9ac) (By similarity).  Autoacetylates (PubMed:20656950).
What are the official names of this protein?
Histone acetyltransferase Rtt109, PcRTT109.
What is the protein family that this protein belongs to?
Belongs to the RTT109 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCME_RICPU
Sequence: MQKRVRNRLITIIICFCSACLGISIILYNLEKNIVFFLPPSKINAIEQGKELRVGGLVKTDSINKIADDKISFVITDNIKDFEILYQGALPALFRKGQGIIAIGQLSNGKFIARQLLAKHDENYRPPQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: IF2_NOSP7
Sequence: MTNGKVRIYELSKELNLDNKELLAICDQLSIAVKSHSSTISESEAENIRTAAEKLAATNVSAKKELGTTSHKPNSPPNGGRNRPAAPHKQQILEIRKPKILRNTTSNAPEASVANNTQAALSEANPPSPPRPFATPASPMKPAAPTRPVPRTQSETQEQPPVTDLEQTPNPSQAPEKVASQKPEKVVPPRPKSEKPQKPQLVAPPARPAAEVAQAEVAQVSDEPVSQADKPILKRDQRLRPVEGDREQIKPRVAKLPTDQSPQSAPQRQARPTPAPTRPEQRGNRPSAPSQLGEGQRPRPARPGESVAAAMPIATPPRQMSGIAGKSQGLGDEPVTPDLLDLKRPSPPRPTKGGKKWVEEEIIDEVKEKAKAGVKGKRIKPILDDEFEEDLLDDDDIDSPATVQVSLSIARPPKPKATRPVQMPGASLASAPTARGSRKPGSKSGSNRDHHNNRRQQEADTKRDRPEKVTITGPLTVQELSDVLAVPDTEIVKILFLKGMAVSITQNLDIPTITLVGKELEIEVETVEREAEARKITEMVGAEDQEYLHRRPPVVTIMGHVDHGKTTLLDSIRKTKVAAGEAGGITQHIGAYHVDVVHEGKPQQIVFLDTPGHEAFTAMRARGARVTDIAVLVVAADDGVRPQTIEAISHAQAAGVPIVVAINKIDKEGAQPERVKQELTQYGLTAEDWGGETIMVPVSAIRGENLDTLLEMILLVAEVGELSANPDRTAKGTVIEAHLDKAKGAVATLLIQNGTLHVGDILVAGSAFGKVRAMVDDRGKRVDIASPSFAVEVLGLSDVPAAGDEFEVFQNEKEARSLASDRADRQRLSRLLQGRVTLTTLSAQAQEGELKELNLILKGDVQGSVEAIVGALKQIPQNEVQIRMLLATAGEITETDIDLAAASNAVIIGFNTTFASGARQAADEAGVDVREYNVIYKLLEDIQDALEGLLEPELVEEPLGQTEVRAVFPVGRGAVAGCYVQSGKLVRNCKVRVRRGGKVIYEGVLDSLKRMKEDAREVNAGYECGVGMDKFNDWVEGDIIESYQMVTKRRTLTLTR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Z518B_MOUSE
Sequence: MKDIGEQLYTTQVNGGPSSLTMSPKQPNRATRTERQEAQTLLYQGSEAEAATMTIATCVQCKSVHKIPTQDLRKGPGQSQDTYVCFKCSLRAVPTQLHFVNNNAGAAHVRNETETISSPVNKFKVRNFKPGKYYCDKCRFSTKDPLQYRKHTLQHEEIRFICSHCSYISYTKGEFQRHLVKHTGIFPYRCEYCDYGAIRNDYIVKHRRRVHERAGAKRPFKTVAKLEPKRTSIPKQSMELSKGPSPRAAFQNKLSDQLSRFSLHANKDKTHNLMLLPELKKYQKDVVCIPNKVTLSEPREVSLLGNKNVEVEVLSPSKEPVHPGMPLTVMAPSELVVPTNCLAQLMDVKVVNGAQQLVLKLFPLEENARLETSRGDGGTSECLSTEKGSGGQKKMLSPEASRSLAVEGNAGDFVGLDRLHSLVQKQLKNVKWVKSCNFFMPNSGVHSQQESFLGSDTIKELQKSHSLCPPRALPSAAIKSHSPASVQNSVPYGPGATVSHFLSKAAVAFADDRRGARSNSQQLLPLASLPSKVPFSGEKGLLPIGESDLEARNRISRPETLVSSDRKLEDKQMESKAVGNTGQVSSVQNKEYLHINITGEDKPRSQQPGDQPGQPKTSETAGATFEGPIISSVFSLSSGSENVPEAIKWNSSTTKIKSIELLRRKIAQLIESCGKPSSLSANSAQRRSIGQAPKLTSKATPKAIQEMSVSLTGPGPTPGPSVGPLQKPPNEDSITGSRQLVPQQVCPQFISANDGKMENRVTRKTPVATPVLIPKGAVLRVLNSSEDAHIIEATCDTPVSIPCSEAQLAGTLPFCPMKQTGSGSQPLTCRSGPADMSPGLETSLRPKSRKEDTICSATAKKMVPVYSTAPGSSDSIRQGRPVSRNLTVSKNKTKQVNSTKKKNKMQANPGRYFKDPPSFFQVARQLRLIAAKPDQLIKCPRRNQPVIVLNHPDVDSPEVTNVMKVINKYKGNVLKVVLSERTRCQLGVRRYHMRLTYQNVAETNHMKRQMMLKMKLKKVHKNNYQVVGSMPDDPAQCVFKCWFCGRLYEDQEEWMSHGQRHLIEATRDWDVLSSKGK
What is the function of this protein?
Through its association with the EHMT1-EHMT2/G9A and PRC2/EED-EZH2 histone methyltransferase complexes may function in gene silencing, regulating repressive post-translational methylation of histone tails at promoters of target genes.
What are the official names of this protein?
Zinc finger protein 518B.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NIFY_AZOVI
Sequence: MTAQPPFGQAPLPAHLALRIALAARSLKGVDTAHLLRALIAAVGEPITEARLRKLRASRLRTRLLETCGEGVQSTLTDRQLHSALGLLKGRGVRMPEDPLPIPEPYRNGEFQDSVRIACASDNGERLDGIFSNCTRFLIYQISPRESRLIDLREPGPCREDEDRHARRAELLADCQLLYTLSIGGPAAAKVVRAGVHPVRLARARPAREIVEELQRVLATAPPPWLAKAMGAEPDQRIRFTQ
What are the official names of this protein?
Protein NifY.
What is the protein family that this protein belongs to?
Belongs to the NifX/NifY family.
Protein: TGT_HAEIG
Sequence: MKYELDKTSGNARRGRLVFERPQGTFSVETPAFMPVGTYGTVKGMTPEEVRATGAEILLGNTFHLWLRPGQEIMRKHGDLHDFMQWHRPILTDSGGFQVFSLGKLRKITEEGVKFQNPINGERIFLSPEKSMEIQYDLGSDIVMIFDECTPYPATFDYAKKSMEMSLRWAKRSRARFDELGNKNALFGIIQGGVFEELRKVSLEGLVNIGFDGYAVGGLAVGEPKEDMHRILEYICPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGIVKIRNAKYRDDTSPLDPECDCYTCKNYTKAYLYHLDKCGEILGARLNTIHNLRYYQRLMAEIRQAIEDDRFDDFVVEFYARMGKPVPPLQLADKS
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KDSB_FLAJ1
Sequence: MKIIAVIPARYASTRFPAKLMQDLGGKTVILRTYEAAVSTKLFDDVFVVTDSDLIFDEIVSNGGKAIMSIKEHESGSDRIAEAVANLDVDIVVNVQGDEPFTEAGPLEQVLSVFKNDPDKKIDLASLMREITNEDEINNPNNVKVVVDQSQFALYFSRSVIPYPREKDAGVRYFQHIGIYAFRKQALLDFYSLPMKSLEASEKLEQLRYLEFGKRIKMVETTHVGIGIDTAEDLERARAMLRDI
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_THISH
Sequence: MPLDTLRIATRKSPLAVWQAEHVAALVKARHPGVRVELVGMTTQGDRILDTPLAKVGGKGLFVKELETGLLEGRADIAVHSMKDVPMELPEGLCLPVILDREDPRDAFVSNTFKSLDELPRDARVGTSSLRRQCQLRHDHPHFQILDLRGNVNTRLAKLDAGEFDAIILAAAGLKRLGFEVRIASEITPEQSLPAIGQGAIGIECRENDPEVMALIGSLDDPDTHVRVAAERAMNARLNGGCQVPIAGYAELTDADTLRLRGLVGEPDGSLILRAELSGPRAEAEALGRAVADLLLHEGAGPILAELGLGPDADRS
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: PANC_SHELP
Sequence: MYTTQDIAAIRTQVRQWKRAGETVAFVPTMGNLHQGHITLVTEALKRADHVVVSIFVNPMQFGQNEDLDAYPRTLAADQAALEAAGAELLFTPTPAIIYPKGMDKQTFVEVPGLSEELCGASRPGHFRGVATIVCKLFNIVQPDVALFGKKDFQQLMVIKAMVEDLSLPIEIVGVDTIRESSGLAMSSRNGYLSEAQKQQAAQLKRTLDEMAEAIAKGQAIPNVVRHAQEQLHQAGFKPDYLSVRNAADLREAQDSDKQLVILAAAFMGSTRLIDNLSFERA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGO1_SCHPO
Sequence: MNFQFINSNINNEDKLPMESLKKKFLKQNREIIKINTQLSIKIRESENEIQDLIQENFTLKSYLVKLEARFRNQSQTEDLLKNFFPEIQTIHKKISQVQSLLKIIEKKCSSDFLEANVKSQFTTCENKDSKEDYQILHNKRLEYVSFNDELKSLETGQPLYCFQDFQKKVHGPPALSEKPGKCILKDKTNAHVNKIPQDEVNYSLPQKNITIFSKELKENEFESINEGETEEEKAKTSNVCVCIPCKSAEQITDLKGQATGDSSPCDFEESQPRINGREKLRRSVKVINYAIPSLRTKLRRDFDLPSDRKRKRHPRGKA
What is the function of this protein?
Plays a central role in chromosome cohesion during meiosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms.  May act by protecting centromeric rec8 from separase degradation during anaphase I.
What are the official names of this protein?
Shugoshin-1.
What is the protein family that this protein belongs to?
Belongs to the shugoshin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes to the centromere. Bub1 is required for centromeric localization (PubMed:14730319). At the onset of anaphase I, it is degraded.
Protein: NDK_PROM0
Sequence: MTKERTFIAIKPDGVQRGYVSEIIGRFEKKGFKLVGLKQLIPSKELAQNHYGVHRERPFFGDLVDFISSGPVVAMVWEGEGVILSARKLIGSTKPLEAEPGTIRGDLAIDIGRNIIHGSDGEDTAKFEIDLWFNEEELCEWETSDLKWRSEN
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQBA_BACSU
Sequence: MSKKSVKARVIKASPPTESTKQIYEDEFADSYDSNILPPPYNLKELKMIAEYSTILQQCVDAYRTNIVGFGFDFEYSFDVNSPDVTNEEKTEAESEWTKLEEFVKYLHFDESAETLLGFVIEDREKTGNGFIEVIRNGENKPAGIEYMDVQNVRVCKLSEPIEVDFTYFEQGQMKSIKREKRFRKYVQMIDGRMVYFKEYGDPRTLNLETGQYDEQTPLEKRANEVVHFKIGSGIYGKPRWIGHIVNLYGARKAEELNFMYFKQGRHIPAAITIENGMLSEDSYTQLQDYMNGLEGVENAHKFLLLEAEGIAKGKNIHGDEEIAPVKVDIKSLAEILQEDALFLEYDQKNRDKIRSAFRLPPLYTGEAQDYNRATADTARKITEEQVFQPERKLITGKLNALFLNDLEIHKVRLQLKGPDFRDPLEIAKVLTPFITAGAVSPNDLRDLAGRVLGKTLEEWPEEEYNRPLGKTNESSVSDPLAALFKSKNGTPNMIGLLKDMRDVLEDLKR
What are the official names of this protein?
Uncharacterized protein YqbA.
What is the protein family that this protein belongs to?
Belongs to the phage portal family. PBSX subfamily.
Protein: EX7L_XYLF2
Sequence: MQHRDEILTPSQLNTLARDLLESAFPLVWIEGELGNVSRPSSGHLYVTLKDAQAQVRCAMFKPKSQWLTFQPREGLRVLARGRLTLYEARGDYQIVLDHLEESGEGALRRAFEQLRIRLEAEGLFDPARKQPLPVHPRRIAVITSPSGAVIRDILSVLMRRFPLVEIELLPSLVQGDTAAAQITHLLGGADSSGRYDAILIARGGGSLEDLWAFNNEQLARTIAAAHTPVISAIGHETDFTLADFAADIRAPTPSVAAELLVPDQRALRQHLGQLQQRLLHLQQHRLDQAIQRADQLGLRLQARNPEMHLRLLAQRQAEAGRRLQQCLHHVLDRAQGQLRNHHTRLYALNPRQQIAGLQKHLKHLNPQQPLQRRLQQEQLRLHGLVRALEAVNPLATVARGYALVRRADNNTLVRDSAQVCVGDVLDTKLAHGQLRVRVEISST
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGX_ECOLC
Sequence: MTQLAIGKPAPLGAHYDGQGVNFTLFSVHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKGLTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR
What is the function of this protein?
Removes maltotriose and maltotetraose chains that are attached by 1,6-alpha-linkage to the limit dextrin main chain, generating a debranched limit dextrin.
What are the official names of this protein?
Glycogen debranching enzyme, Limit dextrin alpha-1,6-maltotetraose-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: TSPY3_HUMAN
Sequence: MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESALEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVEEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS
What is the function of this protein?
May be involved in sperm differentiation and proliferation.
What are the official names of this protein?
Testis-specific Y-encoded protein 3.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SARV_STAAR
Sequence: MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
What is the function of this protein?
Part of the pathway by which MgrA and SarA control autolysis.
What are the official names of this protein?
HTH-type transcriptional regulator SarV, Staphylococcal accessory regulator V.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.