PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_XYLFT
Sequence: MTGLFQLVSSYSPSGDQPAAVQKLVTNFHAGIAKQVLLGVTGSGKTYTIANVVEQIQKPTLVMAPNKTLAAQLYGEFKAFFPHNAVEYFVSYYDYYQPEAYVPASDTFIEKDSSINEYIEQMRLAATKALLSRSDVLVVATVSAIYGLGAPEDYLSLRLILSLGEHIEQRQLIRHLTELQYTRNELDLVRGSFRVRGEVVDVFPAESEMEALRIELFDGEIESLSLFDPLTGQTVRKLQRFSVYPKTHYATTRERTLSAVDTIKDELKEYLELLYGRNKLVEAQRLAQRTQFDLEMMAEVGYCNGIENYSRHLTGKAPGEPPPTLFDYLPPDALLVIDESHVTIPQIGAMFKGDRSRKETLVEFGFRLPSALDNRPLRFEEWEVRSPRSIYVSATPGSYEFRESAGEVIELLVRPTGLIDPEIEIRPVATQVDDLISQINACIKLGDRVLVTTLTKRMAENLTEYLSEQGIRIRYLHSEIDTVERVEIIRDLRLGKFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSTSSLIQTIGRAARSVRGRAILYADKVTRSMRAAIDETERRRQKQKEYNAENGIVPKSVVRPISDILEGARDGVEVKSKGKGRRVDEVPADYGALNQAEIAAQMKVLEQKMYQHARDLEFEDAARIRDQIQRLREAGLG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_HALMA
Sequence: MGLERAFADEPAFVPYLAAGDPNYEASLEYVEALARGGADVIELGLPFSEPIAEGKTIQNAIVRSLEAGMTPDRFFQFVEDLDVDVPLVCMTYYNLIYQYGEGDSESRSDSENASGETASQGPRPFVEKAAAVGIEGLVVPDLPGEEAGPLRTACDEFDLDLVFIVAPTTKGDRLERMLEQVSGYVYVQARLGVTGAREDVDDATEDSLARLSDWDVPKAVGFGIKTGAHAERIVSAGADGIIVGSALVDIVAEGHENGDSTDAVADRLEAKARELKEGALRGAAERPQPERT
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: FOLD_VIBPA
Sequence: MTAQNIDGTLISQTVRSEVAARVKARVAAGLRAPGLAVVLVGEDPASQVYVGSKRRACEEVGFVSKSFDLPASTSEEELLALIDELNNDNEIDGILVQLPLPAGIDTTHVLERIHPEKDVDGFHPYNVGRLAQRIPKLRSCTPKGIITLLDRYNIELRGKHAVVVGASNIVGRPMTLELLLAGCTTTTCHRFTKDLESHVRQADVVVVAVGKPNFIPGEWIKKGAVVVDVGINRLDSGKLVGDVEYDKARESASFITPVPGGVGPMTVASLIENTMLACEQFHTEQ
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DXS_BRUA4
Sequence: MSRPTTPLLDKAPIPEALRALPESDLPQLAQELRAELIDVVSTTGGHLGAGLGVVELTVALHHVFDTPHDRIIWDVGHQAYPHKILTGRRDRIRTLRQTGGLSGFTKRTESEYDPFGAAHSSTSISAGLGMAVASDLSGEKRNVIAVIGDGSMSAGMAYEAMNNAGALDARLIVILNDNDMSIAPPTGAMSAYLARLVSGKTYRSVREAAKQVAKKLPKFLQDKARKSEEYARAFFTGGTLFEELGFYYVGPIDGHNLDHLLPILKNVRDTQEGPVLIHVVTQKGKGYAPAEAAADKYHGVNKFDVITGKQSKPPANAPSYTKIFGTSLIEEARHDDRIVAITAAMPSGTGLDLFGEVFPQRTFDVGIAEQHAVTFAAGLASEGYKPFCAIYSTFLQRGYDQVVHDVSIQNLPVRFPIDRAGLVGADGPTHAGSFDTGFLAALPGFVVMAASDEAELRHMVRTAAEYDEGPISFRYPRGDGVGVDLPERGQLLEIGKGRIVREGTKVALLSFGTRLQECLAAADELGAAGLSTTVADARFAKPLDHDLIRRLAREHEVLVMVEEGAVGGFASHVLQFLATDGLLDRGLKVRALTLPDTYQDHGKPDAMYAEAGLDRTGIVHAVFAALGREAVAAPFSA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PAR4_MOUSE
Sequence: MCWPLLYPLVLGLSISLAEGIQTPSIYDDVESTRGSHEGPLGPTVELKEPKSSDKPNPRGYPGKFCANDSDTLELPASSQALLLGWVPTRLVPALYGLVVAVGLPANGLALWVLATRVPRLPSTILLMNLAVADLLLALVLPPRLAYHLRGQRWPFGEAACRVATAALYGHMYGSVLLLAAVSLDRYLALVHPLRARALRGQRLTTGLCLVAWLSAATLALPLTLHRQTFRLAGSDRMLCHDALPLTEQTSHWRPAFICLAVLGCFVPLLAMGLCYGATLRALAANGQRYSHALRLTALVLFSAVASFTPSNVLLVLHYSNPSPEAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSHEFREKVRAMLCRQPEASSSSQASREAGSRGTAICSSTLL
What is the function of this protein?
Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis.  May play a role in platelets activation.
What are the official names of this protein?
Proteinase-activated receptor 4, PAR-4, Coagulation factor II receptor-like 3, Thrombin receptor-like 3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YPEB_HALH5
Sequence: MIRNVIIGLLAVAVIATGYWGFQEQQQSQILTVQAENGYQRAFHELAYHIDQIEDQLGATMAMNTRRQLTPSLAEVWRLTSLASEEIGQLPLGIVDLSKTEEFLHHLGTFSYKTSIRDLDKEPLTDEEYEKLEKFHDYSKTIKNDLRKTQAMTLKKDMRWLDLNKEFQAQDEPLDNAIVDGFRTMDEHVKGASEVEWGPGMVIRNDHEKKLEKRLEKRKITEEEAKEIALSYVDMEQATDVIVSETGDGLDMYSVIIDDPERQAHYYLDMTQQGGHPIWFLQERQINEQNISLNEASNKAQEFLEEHDKENMQLVDSKQYDSIGVFEFVYLEDNVRVYPDTIKVEVALDEGDIIGYEAMSYLVNHHDRDLEEPELTADEARERLNPRLEVMEDHIALIQNDLGEEVLCYEFFGVINDETYRIYINAEDGEEEKVEKMQEAEPVYDFD
What is the function of this protein?
Required for spore cortex hydrolysis during germination.  Appears to be required for either expression, localization, activation or function of SleB (By similarity).
What are the official names of this protein?
Sporulation protein YpeB.
What is the protein family that this protein belongs to?
Belongs to the YpeB family.
Protein: DCD_SODGM
Sequence: MRLCDRDIEIWLDEGRLDIAPRPPIERINGATVDVRLGNQFRVFRGHTAAYIDLSGPKDEVTAALDRVMSDEIQLVEGEAFFLHPGELALAVTLESVTLPDDLVGWLDGRSSLARLGLMVHVTAHRIDPGWQGRIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: MCS4_SCHPO
Sequence: MRIWFKKVPDGITSSVILSEDHLVDDLKDAIARKFPIRISQYYDAPELSIRVVAPPNASSELQSRELSPNESILFVMETYYPHGQDFNDALLVASPDTSVALRYRSSQLSSSTFESTPPVFSEYPPNIIPTPANETVPRIKQPSIALDSLESPVSAPSRHQSTYSYKGGPLNYNLRNASRTRSHQTLPSSNVNKTGVLLLPRSSRQQTLASRPSLPDLTSADKSQPSDEAESITRKNSIGMSTRSDESTAEKLAKAEVATPTNSRSISHSSLYTKQSGTAGVLPAVNADIDAANRMNPDISSQFPIADNKDPLNADTQAHLGFPSNQIDGIVGTSPVNVLTSPGIGAKAPFASLLEGVIPPINVLIVEDNIINQKILETFMKKRNISSEVAKDGLEALEKWKKKSFHLILMDIQLPTMSGIEVTQEIRRLERLNAIGVGAPKLTQPIPEKDQLNENKFQSPVIIVALTASSLMADRNEALAAGCNDFLTKPVSLVWLEKKITEWGCMQALIDWNGWCRFRGR
What is the function of this protein?
Response regulator that coordinately controls the stress activated wak1-wis1-sty1 MAP kinase pathway and fission yeast cell cycle.
What are the official names of this protein?
Response regulator mcs4, Mitotic catastrophe suppressor 4.
Protein: FENR_IGNH4
Sequence: MRDALVVGAGPAGLTAAATLKQYGVEPLVIEAERVMATVYSYAWKPVENYPGFDGKRAIEIARAFEEMQKFFGVEVVEKERVVKAWKEGDKIVLGTQSGNEYEGKVLIIAIGILGKPRRLGIPNEDAPNVHYIVKDPTAFAGSKVVVVGGGDTAVDTATVLAESGAQVTIVHRRDQFRAPMRSIERMVRAGVKMVLNSVPKEIIAKDGKATALVVTHKEGGETVLPLDHLVISIGFEPPDLEWVKSLGVNMRGKEILVDDKMRTNVKGVFAAGDITPAPKRILVAAAQGYIAGFTAFRYIRTGVW
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: MLTF_PSEAB
Sequence: MFALTAYRLRCAAWLLATGIFLLLAGCSEAKAPTALERVQKEGVLRVITRNSPATYFQDRNGETGFEYELAKRFAERLGVELKIETADNLDDLYAQLSREGGPALAAAGLTPGREDDASVRYSHTYLDVTPQIIYRNGQQRPTRPEDLVGKRIMVLKGSSHAEQLAELKKQYPELKYEESDAVEVVDLLRMVDVGDIDLTLVDSNELAMNQVYFPNVRVAFDFGEARGLAWALPGGDDSLMNEVNAFLDQAKKEGLLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPRYESHFKQSGKQLDTDWRLLAAIGYQESLWQPGATSKTGVRGLMMLTNRTAQAMGVSNRLDPKQSIQGGSKYFVQIRSELPESIKEPDRSWFALAAYNIGGAHLEDARKMAEKEGLNPNKWLDVKKMLPRLAQKQWYAKTRYGYARGGETVHFVQNVRRYYDILTWVTQPQMEGSQIAESGLHLPGVNKTRPEEDSGDEKL
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: ALSI_TAMSI
Sequence: MPSSISWGLLLLAALSCLGPGSLAQDAQETEASKQDQEHPASHKIAPHLAEFALSFYRVLARQSNTTNIFFSPVSIATALAMLSLGTKGDTHTQILEGLDFNLTEMAEADIHQGFQHLLQTLNRPNTQLQLTSGNGLFIDRNLKLLDKFLEDVKSLYHSEAFSTNFTNTEEARQQINSYVEKGTKGKIVELLKELDRDTVLALVNYIFFKGKWKQPFNEEQTREKDFHVDEATTVRVPMMNRLGMFHLHHCSTLASWVLQMDYLGNATAIFLLPDKGKMRHLEDTVTTEILTKFLKNRETTKSQLYFPKVSISGTYDLKDVLSSLGITKVFSSEADLSGVTEEAPLTVSKALHKAVLDIDEEGTEAAGGTVLGNIRSILRYEVIFDRPFLVVIYEHHTKSPLFVGKVVNPTQQ
What are the official names of this protein?
Alpha-1-antitrypsin-like protein CM55-SI.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: TKT_SCHPO
Sequence: MTSSSYTDIDTLAINTIRTLAVDTTAHAKSGHPGAPMGLAPAAHVLFSRIMKFNPAHPKWLNRDRFILSNGHACVLQYIMCHLLGYKLTIEDLKQFRQVGSKTPGHPETHNPDLNIETGAGPLGQGIASAVGLAIGKAHSAAVYNKPGFDLFSNYTFCFLGDGCLQEGVSSEACSLAGHLKLSNLIAVWDNNKITIDGATSMSFDEDVEKRFEAYGWNIVRVANGDTDLDGIEKGFREAMSCTDKPTLINLKTTIGYGSELQGTHSVHGSPLKPEDCVHVKKLFGFDPTKTFQVPPEVYAYYKERVAIASSAEEEYKKMYASYKQSYPDLSNQLERILSRKFPEGWEKHLPVYKPGDKAVATRKLSEIVLDALCPVLPELVGGSADLTPSNLTRWEGAADFQPPSSKLGTYAGRYIRYGIREHGMAGIMNGLAVYGPIIPYGGTFLNFVSYAAGAVRMAALNNSRVIYVATHDSIGLGEDGPTHQPIETFAHFRAMPNINCWRPADGNETSAAYYSALTSDSTPSILALTRQNLPQLENSTIENALKGGYVMLENKEADITLVGTGSEVSLCIDTVKTLETEYNLKARVVSLPCWEVFEQQPESYRLSVIPDGIPAMSVEVWATNGWRRYVHEAFGMHTFGDSGPAPKLYEKFHFTTSGVAQRAKKTVDAYKDIPYIRSPVRRAF
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Probable transketolase, TK.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: GLPE_ACTSZ
Sequence: MAFTEITPERAWDMIQTENAVLLDVRDAERFSYSRAQGAFHLTNQSYGEFQDTYDFDHPVIVSCYHGISSRSIAAFLAEQGYDNVYSVIGGFEGWQRAGLPMETAYGVKPI
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBI_CUSOB
Sequence: MFILKLFVYTVVIFFVSLFIFGFLSNDPRRNPEPEED
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid membrane; Single-pass membrane protein.
Protein: DNAA_PORG3
Sequence: MNYHSTNVNEIWDACLRILQDIVDERAYRTWFLPIIPVSIEGDTLTLQVPSQFFCEFLEGNFVEQLRTVLGRVIGPNASLQYNALVDNSSPKYPGTVTLAGCADGGQAAEQFDVNLLHRHMPNAATHSEAQDFDTQLNSRLNFRNFYQSECNYVARSVAEAIAASPGNTPMNPFFIYGASGVGKTHLCHALGLRVREMHPRLKVLYVSSHLFEMQFTTAARMGTINDFIAFYQQVDVLIIDDIQWLIGKKKTQLAFFQVFNHLYMLGKQIVLTSDKPPVDLNGMEERLVTRMAGATCVKIERPDLKLRREILQQRTLQSGVRLDESVLNFIAENVCDNVRELEGTLVSLITNSVVVGKEIDLTFAKRIVRQAVRLEKKEVTIECIQQAVSRVFQVQIEQMKSKSRKQDIVQARQVVMFLSKKHTAQSLSAIGELMGGRNHATVLHGCRCVTNEMEMNASFRSSVERAEQLIAN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPCB_XENTR
Sequence: MADPAACEPGEDTTTRFARKGALRQKNVHEVKEHKFTARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCETCMMNVHKRCVMNVPSLCGTDHTERRGRIHIKAEIREEVLTVTVGDARNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPTWNESFKFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELLKAGVDGWFKLLSQEEGEYFNVPVPPEGEEGNEELRQKFERAKIGPGTKAVEEKVVNPMPKVDNNETRDRMKVSDFNFLKVLGKGSFGKVILAERKGTDELYAIKILKKDVVIQDDDVECTMVEKRVLALSGKPPFLTQLHSCFQTMDRLYFVMEYVNGGDLMYQIQQVGRFKEPHAVFYAAEIAIGLLFLHSKGIVYRDLKLDNVMLDSEGHIKIADFGMCKENMWDGVTTKTFCGTPDYIAPEIIAYQPYAKSVDWWAFGILLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKDHAFFRYIDWEKLERNEIQPPYKPKACGRNAENFDKFFTRHPPVLTPPDHEVIRNIDQSEFEGFSYVNSDFAKEEEKD
What is the function of this protein?
Calcium-activated and phospholipid-dependent serine/threonine-protein kinase involved in various processes such as regulation of the B-cell receptor (BCR) signalosome, apoptosis and transcription regulation.  Plays a key role in B-cell activation and function by regulating BCR-induced NF-kappa-B activation and B-cell survival.  Required for recruitment and activation of the IKK kinase to lipid rafts and mediates phosphorylation of card11/carma1, leading to activate the NF-kappa-B signaling.  Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates isoform p66Shc of shc1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer.  Acts as a coactivator of androgen receptor (andr)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-6' of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation (By similarity).
What are the official names of this protein?
Protein kinase C beta type, PKC-B, PKC-beta.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane; Peripheral membrane protein.
Protein: FOLD_PARUW
Sequence: MIIDGKRIAEEIQLEIKELIQQSLCRPPCLAVLIVGSHPASQIYVNRKTAACKAVGIASIKCELPFTISEEELIREVEKLNVDPQIDGILVQLPLPPHINSNRVNYHIDPQKDVDGFHPLNVGKMLIGELDGFLPCTPFGIKTLLERTGIEVCGKHALIIGRSNIVGKPMAALLMQSYPGGNATVTVAHRYTKNLKELCLQADLIIVAIGQPKLITADMVKEGVIIVDVGINKIHDSSKKNGYQIVGDVDFVNVAPKCAFITPVPGGVGPMTIAMLLYNTLLSYSKSQNLNL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: STAC3_HUMAN
Sequence: MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI
What is the function of this protein?
Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization.  Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction.  Probably functions via its effects on muscle calcium channels (PubMed:23736855, PubMed:29078335).  Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane.  Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane (By similarity).  Slows down the inactivation rate of the calcium channel CACNA1C (PubMed:29078335).
What are the official names of this protein?
SH3 and cysteine-rich domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma, T-tubule. Note=Co-localizes with CACNA1S and CACNA1C on T-tubules.
Protein: RL28_STRSY
Sequence: MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKPKKVWASARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RL5_HALLT
Sequence: MSESESASHEMREPYLEKVVVHMGVGQGGEPLADAEEIIEEITDQQSVRTTSKRTIAEFGIRKGDPIGVKVTLRGEDAHAFLDTALELADISKSQFDDTGNLSFGVEDHTDFPSQEYDPNIGIYGLDVTTTIVRPGYRVSKRDKATASIPSKHRMTAEDATAFLETNFDVEVTE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MSRAB_TREPA
Sequence: MLANLQHLSDIQYRVTQQSATETPFKNEFWNSYQPGFYLDVVSGELLFLSEDKFDSGCGWPSFSAPAYARAVIEKEDRTHNMLRTEVRSRNANSHLGHVFKDGPPERGGLRYCINSAALRFVAREEGTALFAAGCFWSTEAYFRRVKGVLRVRVGYTGGTTKSPTYRNVCTGTTGHAEAVEILFDPQVISYEDLLKHFFRMHDPTSLNKQGGDVGTQYRSAIFYLSGTQKQQAETLMGRYAGAGKFTRPLVTTLEEARDFYPAEEYHQDYLTKNPGGYCHVSLHLASEPLE
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB/MsrA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrA Met sulfoxide reductase family.
Protein: PUP1_CANGA
Sequence: MSDSREIKKPWWFKKAKEWADEFYTRDQKLEDSDRRDLSKKYATISKASVVGAATGLSAGLGGPYAYRYYTTGALKGVKLPRTILLGVVSMVIMRNVAAKIAWDKELKKLDPSGELKQNYKSAHKTVDDVSLSDNSTSVQKKYGMMKFLKYRTAPRWAMYFEGTYQHPDRKFPNPDQMVQDLKGSRRAFPPFFSKADKFWHQIDRKDNDHT
What is the function of this protein?
Mitochondrial protein that contributes to the enhanced virulence of C. glabrata strains that acquired azole resistance.
What are the official names of this protein?
PDR1 up-regulated protein 1.
What is the protein family that this protein belongs to?
Belongs to the PUP1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PYRH_SHEFN
Sequence: MSTNPKPAFRRILLKLSGEALMGEEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYTWTEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSADPMKNPEAVKYDTLSFAEVLESELKVMDLAAFTMARDHNMPILVFNMNKPGALRRVIMGEKEGTIISSKQPA
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA1_STAA2
Sequence: MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGDDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR16_GALSU
Sequence: MLKIRLKRCGRKKQTSFKIVVMNNLDKRDGQAIEELGFMNPRTKEKYLNINKINHYLRLGAKPTKTVFDLLNKAKII
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATL61_ORYSJ
Sequence: MELPWLDLPFTLLTLLLATRLAYDYYGVVAATFTGSFSLQIFLFYCFARWYRHTIAARAAADADGDGGGGAVADEEAAPPVLIPLLEGRGGGGGGAGAASSLANRCFAVVFMVFVPLVIVVFERSQADVVAYALCLANILVMVVWLSPDAAADPASAAKSFLRLSDDEDEGSCSGSGHGAAEDKCCVCLAGMREAQALRDLPRCGHRFHAKCIGKWLTAHPTCPVCRTTAVPPPAPLPASGDHADDAITPV
What is the function of this protein?
Possesses E3 ubiquitin-protein ligase in vitro.
What are the official names of this protein?
E3 ubiquitin-protein ligase Os06g0535400, RING-H2 finger protein Os06g0535400, RING-type E3 ubiquitin transferase Os06g0535400.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CYVNB_VIOIN
Sequence: GSIPACGESCFKGKCYTPGCTCSKYPLCAKN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide vinc-B.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family.