PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_XANAC
Sequence: MTASPDPAQRIDALRRRIEDANYRYHVLDEPQMADADYDKLMRELEALERAHPELASADSPTQRVGHLAASRFAEVRHAMPMLSLGNAFSDEEVTEFVRRISERLEVRQPLFSAEPKLDGLAISLRYENGEFVQGATRGDGATGEDVSANLRTVKAIPLRLRGEGWPRVLEVRGEVYMPRAAFEAYNAQMRAQGGKILANPRNGAAGSLRQLDARITAQRPLSFFAYGVGEVSEGALPQAHSAILAQLRAWGFPVSALVEVVQGSDGLLAYYQRIGEARDGLAFDIDGVVYKLDDLAGQREMGFVSRAPRWAIAHKFPAQEQSTTVEAIEIQIGRTGAATPVARLKPVHVAGVIVTNATLHNADQIARLDVRVGDTVIVRRAGDVIPEVAAVVADQRPPGTQAWQMPTQCPVCGSEIVREEGQAVWRCSGELTCPAQRKEAFRHFVSRRAMDVDGLGEKFIEVLVDSGLVKGVADLYLLSVDQLLQLRLISTADSPHAFLREAREHLASGAYAQLEASVVGIGVDLAGERDVPQTWQADLLRAGLPSFDWNRKKIATKWAENLIEAIEISRDTTLERFLFALGIEHVGESTAKALSAWFGDLELIRHLPWPLFKRVPDIGGEVARSLGHFFDQAGNQKAIDHLLARKVRIGDTHPPSPKLRGELSLANLLEDLEIPKVTPIRAAQIATAFGSIDALRNGGPEPLVEAGVPQSVAESLAAWLLVPANDTLAVNAQRKLSELLAMLPEAGEEKTGPLDGQTVVITGTLAALTRDAAKQRLEALGAKVAGSVSKKTAFLVAGEEAGSKLDKAQSLGVEIWDEARLLAFLGDHGQQP
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SYL_HISS2
Sequence: MQEQYRPDLIEADVQKYWAEKKTFKAVKDPFKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVISRYQRMNGKNVLQPMGWDAFGLPAEGAAIKNKTAPAKWTYENIEYMKNQLKVLGFGFDWDREITTCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCPNDETVLANEQVHEGGCWRCDTPVEQKEIPQWFIKITDYAEQLLSDLDQLPEWPDMVKTMQRNWIGRSEGVEITFNVAHSDQTLTVYTTRPDTFYGVSYLAVAAAHPLAENAAKNNPELAAFIHEAKNTKVAEAELATMEKKGMATGLYAVHPMTGKQLPIWVANFVLMHYGTGAVMAVPAHDQRDYEFAQKYQLPLFPVIKPADNSAWDFSKQAYTEHGITINSAEFDGLDFEATFNGIADKLEKIGVGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVVAPLQDLPIVLPEDVVMDGVKSPIKADPEWAKTTYNGQVALKETDTFDTFMESSWYYARYTSPQYQQAMLDADETNYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGFVTSDEPSKKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLERDEKGRIIKAVDDEGHELVHSGMTKMSKSKNNGIDPQEMVEKYGADTVRLFMMFASPAEMTLEWQESGVEGANRFLRRLWNLVFEYNQNPAQTALDPTALSVEQKALRREVHKTIAKVSDDIGRRQTFNTAIAAIMELMNKLTKASLSNEQDRAVMAEALNAVVRMLYPITPHICFQLWQDLGNESAIDFAPWVIADAEAMVEDEKLVVIQVNGKVRAKVTVPADMSEDEIKQVALAEENVQKFLNGLTVVKTIYVPGKLFSFVAK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_BACC0
Sequence: MKAGIHPDYKKVVFMDTNTGFKFLSGSTKGSNETVEWEDGNTYPLLKVEISSDSHPFYTGRQKFATADGRVDRFNKKYGLK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: IAAC3_WHEAT
Sequence: MACKSSCSLLLLAAVLLSVLAAASASGSCVPGVAFRTNLLPHCRDYVLQQTCGTFTPGSKLPEWMTSASIYSPGKPYLAKLYCCQELAEISQQCRCEALRYFIALPVPSQPVDPRSGNVGESGLIDLPGCPREMQWDFVRLLVAPGQCNLATIHNVRYCPAVEQPLWI
What is the function of this protein?
Alpha-amylase/trypsin inhibitor.  It could be involved in insect defense mechanisms.
What are the official names of this protein?
Alpha-amylase/trypsin inhibitor CM3, Chloroform/methanol-soluble protein CM3.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I6 (cereal trypsin/alpha-amylase inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_PEPNI
Sequence: MNQGTIIKVVGPVVDVEFPSGLLPNINNALHISSDEQPEDKKTGHDFKVVLEVAEHLGGNIVRAIAMSSTDGLMRGMVVTDQESPITVPVGDATLGRLMNVVGDPIDEAGEVPSETRWPIHRSAPTYVQQNPSKEILETGIKVVDLLCPYVKGGKIGLFGGAGVGKTVLIQELIRNIAYEHGGYSVFAGVGERTREGKDLLVEMRESGVIDKTSLVFGQMNEPPGARMRIALTGLTVAEYFRDEQNQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGTMQERITSTDKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLERSISEKGIYPAVDPLASTSRILDPRIVGEEHYEIARDVQEVLQEYRELQDIISILGMDELSDEEKLTVARARRIERFLSQSFFVAEQFTGNPG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TSK_DANRE
Sequence: MASLLCLFFSLLGLAAIGAVKNCHPQCRCEVETFGLFDSFSLTKVDCSRIGPGNTPVPIPLDTSHLDLSLNSTTSISDTMLSGPGYTTLVSLDLSSNLIAQISPKAFSKLRYLETLDLSSNALEGLSDGCFTGLPLVELDLSENQFKEFNLDLFTTRTQDLPIMVDLSRNLLTSIFRRTPGHPLYIKSLMLAGNQLKTVPKLNGIPLQYLNLDGNLISSIDTGAFDSLTELVHLSLSGLSELTLIHPGAFRSLKNLQALDLSNNSQLKTLNPNVFSGLVSLQELNLSNTAVTPLSRTVFMQMPNIKSITLGPNVHCWKTHMQGQFHRQIGQAKPNDILTCDNAGLIL
What is the function of this protein?
Contributes to various developmental events through its interactions with multiple signaling pathways (By similarity).  Dorsalizing factor which functions as an inhibitor of bone morphogenetic proteins during gastrulation (PubMed:15363410).
What are the official names of this protein?
Tsukushi, Leucine-rich repeat-containing protein 54, Z-TSK.
What are the subcellular locations of this protein?
Secreted.
Protein: APNUC_BPT5
Sequence: MVIYEGNRFVAICRPGLLANYLNQVSPEYKGVINIYEGKAHYKINAVVARELAFQFLTFASCDIQVMGEALIAENEDDFINIFRKVYTERLIMKGAYIQSTAESIETAFRKVAQ
What is the function of this protein?
Performs endonucleolytic cleavage at abasic sites, which are generated by the base-excision activity of host Ung (PubMed:34074772).  The cleavage generates a 5'-deoxyribose phosphate and 3'-hydroxyl end (PubMed:34074772).  The sites are specifically recognized through the formation of a complex with host Ung (PubMed:34074772).  The viral endonucleolytic activity damages the host DNA, blocks host DNA replication and induces cell division arrest (PubMed:34074772).  This may provide an advantage for the phage and save nucleotides for the viral replication since it specifically targets the host DNA, which possesses more misincorporated uracils than the viral genome (Probable).
What are the official names of this protein?
DNA-(apurinic or apyrimidinic site) endonuclease, AP endonuclease, Apurinic-apyrimidinic endonuclease, Protein 015.
What is the protein family that this protein belongs to?
Belongs to the apurinic/apyrimidinic endonuclease family.
Protein: GRK7_ICTTR
Sequence: MDMGGLDNLIANTAYLQARKTDSDSRELQRRRRSLALPGPQGCAELRQSLSPHFHSLCEQQPIGRRLFRDFLATVPKYSQAVAFLEDVQNWELAEEGPAKTSTLQQLAATCARDPGPQSFLSQDLATKCRAASTDEERKTLVEQAKAETMSFLQEQPFQDFLASPFYDRFLQWKLFEMQPVSDKYFTEFRVLGKGGFGEVCAVQVRNTGKMYACKKLDKKRLKKKGGEKMALLEKEILEKVNSPFIVSLAYAFESKTHLCLVMSLMNGGDLKFHIYNVGTRGLAMSRVIFYTAQMTCGVLHLHGLGIVYRDLKPENVLLDDLGNCRLSDLGLAVEVQDDKPITQRAGTNGYMAPEILMDKASYSYPVDWFAMGCSIYEMVAGRTPFKDFKEKVSKEDLKERTMKDEVAFHHENFTEETKDICRLFLAKKPEQRLGSREKADDPRKHPFFQTVNFPRLEAGLVEPPFVPDPSVVYAKDVDEIDDFSEVRGVEFDDKDKQFFQRFSTGAVPVAWQEEIIETGLFEELNDPNRPSGDGKGDSSKSGVCLLL
What is the function of this protein?
Retina-specific kinase involved in the shutoff of the photoresponse and adaptation to changing light conditions via cone opsin phosphorylation, including rhodopsin (RHO).
What are the official names of this protein?
Rhodopsin kinase GRK7, G protein-coupled receptor kinase 7, G protein-coupled receptor kinase GRK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: DNAB_BACSU
Sequence: MADYWKDVLPVDPYVVKSRSMLQDIDRQIITQLYQPLIGPVAFSLYMTLWGELEQNRLWGGESTHRQLMGMTQSNLKTIHQEQGKLEGIGLLKVYMKESERQERLFIYELLPPLRPNEFFEDGMLNVFLYNRVGKTKYQQLKQFFTHPAISEDAKDITRPFNHAFESLQPSEWKLTSDMEETVRLAEGSEYTSVGQSPSYTITEDVFDFDLFLAGLSETMIPRKAMTQQVRDTIKKLSYLYGIDPLQMQNVVMSAIDERDVITTEALRKAASDWYQIERNGQLPDLVEKTQPVHLREGEQPAEEDSLDGKLIALLEAISPKKLLQDIADGTEPSKADLKIIEEIMFEQKLEPGVTNVLIYYVMLKTDMKLSKNYIQKIASHWARKKVKTVREAMKLAIEENRQYLEWAEGKTKSSKRNQKVIREEKLPDWMTEKETASDSESGQQKLHPQDLEEQKKKMMEEMQKLKKYSAY
What is the function of this protein?
Probable component of primosome involved in the initiation of DNA replication.  It is essential for both replication initiation and membrane attachment of the origin region of the chromosome and plasmid pUB110.
What are the official names of this protein?
Replication initiation and membrane attachment protein.
Protein: Y1214_ORYSJ
Sequence: MGDQKRSFINVMIGDFVAVPTKFANFIRGQISEVVKLEVPNGKTYDVQVAKEHNELVLRSGWGAFARDYELKQCDILVFAYSGSSRFKVRIFNPSGCEKELSCVMMNNTPCGHEGSMSYHDNHLQSPSESSSFFNISLPPHSPFQELSGVDSTSLLVSDPPNMQQFCLRCSWTNPKRLAKPSLAIASLSHQHLAFDKTRCMFILKIENDTLKTILKMFAKNVQGLISGVAKLEVPDGKTYDVEISKEHNELVFRSGWEVFAIAYELEQGDILAFGYSGNSHFKVQIFNPSNCEKELSCVVMNRSISDDNHRQSPRRERMNKPSTTCMDCITNHYWLHMDDRERYFFKVMMSVSDIKDELAIPKKFAANVRGKIPEQVRLEVSDDVPSSEDIKDPMSSGGLQKSKKSCYVLPMLYNMTSAQESEVLALEKKIQPQIPLYITAMDKTSVASGSLVFCKDYAVRYLLDQNRTIKLCQSGGSKTWDISLDMDTDDLYALSTGWLDFFRCNLLQEGDICVFEASKSKRGVALTFHPFKESHCPKSSEYTLSTKSPTRRVPKRDYFATNLTNLTDQQERKCFSVKYASKYLPHKDQNMRLRLPETKYKCKAALHIDTSTNLHKLLKGWGKFVNDNKLEIHDICLFQLMKNKKKLTMTVHIIRKGECS
What are the official names of this protein?
B3 domain-containing protein Os12g0591400.
What are the subcellular locations of this protein?
Nucleus.
Protein: TOM20_MOUSE
Sequence: MVGRNSAIAAGVCGALFIGYCIYFDRKRRSDPNFKNRLRERRKKQKLAKERAGLSKLPDLKDAEAVQKFFLEEIQLGEELLAQGDYEKGVDHLTNAIAVCGQPQQLLQVLQQTLPPPVFQMLLTKLPTISQRIVSAQSLAEDDVE
What is the function of this protein?
Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins.  Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity).  Required for the translocation across the mitochondrial outer membrane of cytochrome P450 monooxygenases.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM20 homolog, Mitochondrial 20 kDa outer membrane protein, Outer mitochondrial membrane receptor Tom20.
What is the protein family that this protein belongs to?
Belongs to the Tom20 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: DNLJ_ALKMQ
Sequence: MDQMKEMEQLVKQLNEYSYKYYVLDQPIVSDKEYDSLYDQLIELEEKTGHVLLDSPTQRVGGEPLKKFQSHQHVALLWSLDKAKTAEELVAWEQRIKKKLESNHEIEYIVEYKFDGLTLNLTYENGELVQAATRGNGVVGESIIEQVKTIQAIPLGVDFNNKMEIQGEGLMAISTLAQYNKTAKEPLKNPRNAAAGALRNLDPKVTAKRKLGAFCYSIGYYEGMEFETHIQMIDFLKKNRFPVSNYIKSCKGIDQVIEQIREVEAGMKELDYLTDGIVIKVNDLRTREILGYTQKFPRWAIAYKFEAQEVTTKLEAVLWQVGRTGKLTPAAQLEPVEIAGVTVSRATLNNWEDIQRKKVKVGCQVWLRRSGDVIPEIMGAIEETCEEAVEIEKPQHCPACDSEIVHRGVHIFCPNSLSCKPQLVSRIVHYASRDAMDIEGFSEKTAEQLFEALGLKNIAALYELKYEDLIQLERFGDKKAKNLLDAIEESKTCKLDAFIYALGIPNVGRKTAADLANYFGDLEKIQRANYDELVVLPDIGGIVAQSIVGFFEDEKIIKSIELLLAEGIKPQHKMKNRQESIFSGKTVVVTGTLENYGRKEIQTLLEEQGAKVSGSISKNTDFVIAGDNAGSKLKKAQEILESGVETNLQILDEAAFEALL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AROC_EXISA
Sequence: MRYLTAGESHGPGLTVIIEGAPAGLAIDISQINAELKKRQSGYGRGRRMQIESDQVEVRSGIRHGVTTGAPITFWIENKDHTHWKHVMQAEPIESDIEVKRRVSRPRPGHADLVGGMKYDHRDLRDVLERSSARETAARVAVGAFCKQLLQQVGVSLFSYVKVIGGERAESRTFDSLQEAQAVVDASPVRTLDEAAALRMMRRIDEAKANGDSIGGIVCTEVHGVVPGLGSYVQYDRKLDAKIAQAVMSVNAFKGVEFGEGFEMAYRPGSEVMDPIAYGDNGYTRLSNHLGGFEGGMTTGMPILCSAVMKPIPTLYKPLQSVDIDTKEAFLAQIERSDSCAVPAASLVVEAVIAFEIAKEMCETFGHDTMERIKHRVDEYREELRVW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RGAP1_HUMAN
Sequence: MDTMMLNVRNLFEQLVRRVEILSEGNEVQFIQLAKDFEDFRKKWQRTDHELGKYKDLLMKAETERSALDVKLKHARNQVDVEIKRRQRAEADCEKLERQIQLIREMLMCDTSGSIQLSEEQKSALAFLNRGQPSSSNAGNKRLSTIDESGSILSDISFDKTDESLDWDSSLVKTFKLKKREKRRSTSRQFVDGPPGPVKKTRSIGSAVDQGNESIVAKTTVTVPNDGGPIEAVSTIETVPYWTRSRRKTGTLQPWNSDSTLNSRQLEPRTETDSVGTPQSNGGMRLHDFVSKTVIKPESCVPCGKRIKFGKLSLKCRDCRVVSHPECRDRCPLPCIPTLIGTPVKIGEGMLADFVSQTSPMIPSIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMIHLQRVAQSPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLLSLPLEYWSQFMMVEQENIDPLHVIENSNAFSTPQTPDIKVSLLGPVTTPEHQLLKTPSSSSLSQRVRSTLTKNTPRFGSKSKSATNLGRQGNFFASPMLK
What is the function of this protein?
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis.  Required for proper attachment of the midbody to the cell membrane during cytokinesis.  Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity (PubMed:10979956).  Has a critical role in erythropoiesis (PubMed:34818416).  Also involved in the regulation of growth-related processes in adipocytes and myoblasts.  May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation.  Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA.  Essential for the early stages of embryogenesis.  May play a role in regulating cortical activity through RHOA during cytokinesis.  May participate in the regulation of sulfate transport in male germ cells.
What are the official names of this protein?
Rac GTPase-activating protein 1, Male germ cell RacGap, MgcRacGAP, Protein CYK4 homolog, CYK4, HsCYK-4.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasmic vesicle, secretory vesicle, acrosome. Cleavage furrow. Midbody, Midbody ring. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with RND2 in Golgi-derived proacrosomal vesicles and the acrosome (By similarity). During interphase, localized to the nucleus and cytoplasm along with microtubules, in anaphase, is redistributed to the central spindle and, in telophase and cytokinesis, to the midbody ring, also called Flemming body. Colocalizes with RHOA at the myosin contractile ring during cytokinesis. Colocalizes with ECT2 to the mitotic spindles during anaphase/metaphase, the cleavage furrow during telophase and at the midbody at the end of cytokinesis. Colocalizes with Cdc42 to spindle microtubules from prometaphase to telophase.
Protein: ASSY_CLOBL
Sequence: MKEKVVLAYSGGLDTSIIIPWLKENYDLDVIAVCVNVGQGDDMDYVKTKAIKSGASKIYVEDVKEEFVVDYLYKAIKSEALYEQDYMLGTSFARPLMAKKLVEIAHKEQAKYICHGCTGKGNDQVRFEVGVKAQDPTIKIIAPWRIWDIKSREDAIDYAKKVGVEVPVTKKKIYSVDRNLWHVSHEGGDLEDLKNEHKEDMYFMVTPPEKAKDEPTYLEIYFEKGVPVKINGEFLNPVDIIDKLNTIGGENGIGIADIIENRLVGMKSRGIYETPAGTLLYAAHKKLESVTLDKYTYQYKKLVSAQYGELVYNGLWFTALREAIDAFVDKTQENVTGTVKLKLYKGNIKPCSVDTEYALYDEGISSFGESELYSHKDAEGFINLFGLPCKIKALKNF
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_BORRA
Sequence: MKTKVGFNRLDRKSSHRKALLKNMVISLFRHERITSTKAKLSEVRRFAEKLITRAKVDSVHNRREISKFIHDKYILNKLFTKISPIFKERKGGYTRVIKLGQRYGDAAEMAILELVDKTLGEK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: OSPF_SHISS
Sequence: MPIKKPCLKLNLDSLNVVRSEIPQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPNYSDICQFFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAPGEYPASDVRPEDWKYVSYRNELRSDRDGSERQEQMLREEPFYRLMIE
What is the function of this protein?
Catalyzes the removal of the phosphate group from the phosphothreonine in the mitogen-activated protein kinases such as MAPK2/ERK2, MAPK3/ERK1, MAPK8 and MAPK14 in an irreversible reaction, thus preventing the downstream phosphorylation of histone H3.  This epigenetic modification results in inhibition of the transcription of a specific subset of pro-inflammatory genes, and ultimately to a reduced immune response against the invading pathogen.  The diminished immune response enhances the bacterium's ability to disseminate and multiply within the host (By similarity).
What are the official names of this protein?
Phosphothreonine lyase OspF, Effector protein OspF.
What is the protein family that this protein belongs to?
Belongs to the phosphothreonine lyase family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system (TTSS). Localizes in the nucleus of the infected cell (By similarity).
Protein: Y4148_CUPNH
Sequence: MPFEFIDAAHAGQAGSDPLQDELALLDLAAQGRQVAQLWEAPLSLVVPRTYLRHAALETARADFAQQGCPVFLRMSGGGLVPQGPGILNLSLAYTVEQPPGARSDAVYLHLCEVIGDALQSLGVDTHWQAVAGSFCDGRYNLAWGPPEAARKIAGTAQYWRRAPAAMQTADGQRHLVLAHAVLLVSAGPVQINARANAFEAAIDSGRHYDAGKVVSVREALLASGRAVDDDAALMAQVSDALRRSVGQTPPPA
What are the official names of this protein?
Uncharacterized protein H16_B0148, ORF 8.
Protein: CAPSD_HASV2
Sequence: MASKSDKQVTVEVNNNGRNRSKSRARSQSRGRGRSVKITVNSHNKGRRQNGRNKYQSNQRVRKIVNKQLRKQGVTGPKPAICQRATATLGTIGTNTTGATEIEACILLNPVLVKDATGSTQFGPVQALGAQYSMWKLKYLNVKLTSMVGASAVNGTVLRISLNPTSTPSSTSWSGLGARKHMDVTVGRNAVFKLRPSDLGGPRDGWWLTNTNDNASDTLGPSIEIHTLGKTMSSYKNEQFTGGLFLVELASEWCFTGYAANPNLVNLVKSTDHEVNVTFEGSKGTPLIMNVAEHSHFARMAEQHSSISTTFSRAGGDATSDTVWQVLNTAVSAAELVAPPPFNWLIKGGWWFVKLIAGRTRTGTKQFYVYPSYQDALSNKPALCTGGVTGGVLRTTPVTTLQFTQMNQPSLGHGEHTATIGSIVQDPSGELRVLLTVGSIMSPNSADRQVWLNKTLTAPGTNSNDNLVKIAHDLGHYLIMQGFMHIKTVEWYTPDFQPSRDPTPIAGMSVMVNITKKADVYFMKQFKNSYTNNRHQITSIFLIKPLADFKVQCYMSYFKRESHDNDGVANLTVRSMTSPETIRFQVGEWYLLTSTTLKENNLPEGWVWDRVELKSDTPYYADQALTYFITPPPVDSQILFEGNTTLPRISSPPDNPSGRYMESHQQDCDSSDDEDDCENVSEETETEDEEDEDEDDEADRFDLHSPYSSEPEDSDENNRVTLLSTLINQGMTVERATRITKRAFPTCAEKLKRSVYMDLLASGASPSSAWSNACDEARNVGSNQLAKLSGDRGHAE
What is the function of this protein?
The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions.  This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry.  The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34.  This forms contains only 30 spikes located on the icosahedral 2-fold axes.  Plays a role in the attachment to target host cell.  This attachment induces virion internalization through clathrin-dependent endocytosis (By similarity).
What are the official names of this protein?
Capsid polyprotein VP90.
What is the protein family that this protein belongs to?
Belongs to the astroviridae capsid polyprotein family.
What are the subcellular locations of this protein?
Virion.
Protein: ISPE_BURVG
Sequence: MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARATDVPGVPEESDLVVRAANLLKAHTGTVAGVDIEIDKCLPMGAGLGGGSSDAATTLLALNRLWQLDLSRAELQSLAVKLGADVPFFVFGKNAFAEGIGEELAEVQLPTRWFLVVTPRVHVPTAEIFSDELLTRDTKPVTIADFLARRNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLYNVTPSRMTGSGASVFAVFRSRHEAEAVKANLPTGWNGAVAESLNEHPLFAFAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: GLGA_FRATT
Sequence: MRVLHVCSELYPILKTGGLADVTAALPPALAGFGVDSRVLVPGFPAFINAIKDKQLLINIPSRFGAEEINIFLAKISNTKIDIYVIDAPSLFARPGNPYADSSNQAYADNYLRFALLGWVAARISEGLDAKWKPEIVHSHDWHAGLVPAYIKASELASGKKAVKTVFTVHNLAYQGLFPMSVFAELDLPGIFLSMNGLEFYGQVSFMKAGLYFADKITTVSPTYAKEIQIYEQGCGLEGLLADRHNDLYGVLNGVDPQIWNPKKDSLIATNYSSTTVATGKAKCKLALQQMMGLAEKEDALLFGIVTRLTEQKGLNLLIEAIGEITSRGGQIVLLGSGDKALEEVFLAAAKKYSKSIAVQIGYDEEQAHRIIAGSDVIMVPSRFEPCGLTQLYGLTYGTLPLVHKVGGLADTVIDSSLENLADGTATGFVFDEFSVESLTLAIRRAFALYNRKTDWKKVRKTAMQQQVTWDSSAEKIYQIYKNLVRENN
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: HFQ_YERPE
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNTPSGSTNNYHGSNPSAPQQPQQDSDDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq, Yersinia multiple regulator, Yersinia regulator for pleiotropic phenotype.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: YDHJ_BACSU
Sequence: MEISDIIYGQHHIDGVLEELIKSAPVQRLKGIYQGGASFLVNRKWNVTRYEHSIGVMLLIKKLGGTIEEQIAGLLHDVSHTAFSHVVDVVFENQAEDYHENIFQQVIVHSEIPDILQKHGYHTEELLSDDSRWTLLEQPAPELCADRTDYTLRDMYRYGHINLHEAQTFLDHLIVRNGRMFPDSIEAAEWFVSVYYKEVIDFFLNPVNVYGYEYLARALKAALRHDVISAEDLLKTDQEVLNILRASKNEEVLSLLTSIHPGIQVIEDDIQYDFHQKKKMRLIDPSIFLDDKWIKSSGVSEKVRKMGEAAYQKAKKGVYIKILKQ
What are the official names of this protein?
Uncharacterized protein YdhJ.
Protein: RECF_SHIDS
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSMLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNESGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELILLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y869_HAEIN
Sequence: MPIMDLLNTRNKNMISLLIISFGRYQEVLETFACVNKYHGNKIELLFLDNNPERELEADLSSIVENNSGILFSYFHTGENLGVAEGRNFLIEKAQGDILITLDDDVEIEDITLLIQKVTDYMANNAKVGALAFNIKNYFTRKALSHEIPHGNKKLDFSQNLLTYYFIGAGHAIREKSLSKSGALP
What are the official names of this protein?
Uncharacterized protein HI_0869.