PharMolix/UniProtQA huggingface dataset:
Protein: GCS2_BURL3
Sequence: MALETFVNSEPFTFGVELEIQVVNTHNYDLTKAASDLMRLIQGETFPGNITPEITESMIELSTGICHSHEQAVSELHAIRDVLVKAADQLNVGLAGGGTHAFQQWSDRQIYDAPRFQYISELYGYLAKQFTVFGQHVHIGCPDPDSALFLLHSMSRFIPHFIALSASSPFVQNVDTGFHSARLNSVFAFPLSGRAPFVLTWDSFEEYFTKMVNTGVVNSMKDFYWDIRPKPGYGTIEVRVMDTPLSVDRAAAIACYIQTLARYLLTDRPLKLSEDDYLVYTFNRFEACRFGLEGTCVNPQTGERRTIAEDILDTLDRIAPHAAALGSRAALDEIGALANARVNDASWLRTVFKQEKSLNETVRQQCLRWRE
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: NASP_HUMAN
Sequence: MAMESTATAAVAAELVSADKIEDVPAPSTSADKVESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEEKPKEVSEEQPVVTLEKQGTAVEVEAESLDPTVKPVDVGGDEPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVTTEAAEASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEEMPNDSVLENKSLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQSCLNLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFSKSIEVIENRMAVLNEQVKEAEGSSAEYKKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPGGGGSSVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKQEPEVNGGSGDAVPSGNEVSENMEEEAENQAESRAAVEGTVEAGATVESTAC
What is the function of this protein?
Required for DNA replication, normal cell cycle progression and cell proliferation.  Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity.  NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
What are the official names of this protein?
Nuclear autoantigenic sperm protein, NASP.
What is the protein family that this protein belongs to?
Belongs to the NASP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SPEE_SULIL
Sequence: MFGWHWLLEWQTPYEFHGHLIEKVFAEEKTPYQHVTLVEFTRFGKGLIIDGKVQSTLYDEHIYHELLVHPLLLSLPKPPKNVLILGGGEGATLREVLKYKSVEKAVMVDIDEKVIEFAKKYLYEWHQGAFEDKRTSLVITDGLKFINETKDKYDAIILDLTDPIKDSTSYMLYTKEFYEKLRGILNQGGGIVTQATSPSFSLEVYVTIYNTIKEVFKEASASYTYMASFDGLWGFVYGGVRPDLLSEDEVNSRIRERISGQLRFYDDYSHKISFSLPKNIKSEFKKITKVSTEKDPIYVPA
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDBM_LYCMC
Sequence: MNKKTLLVIFFVTMLIVDEVNSFRFGSFLKKVWKSKLAKKLRSKGKQLLKDYANRVLNGPEEEAAAPAERRR
What is the function of this protein?
Amphipathic peptide that shows bradykinin potentiating activity and antimicrobial activities against bacteria and fungi.  Has higher antibacterial activities against Gram-negative than against Gram-positive bacteria.  Also inhibits NADPH oxidase-dependent superoxide production (IC(50) is 0. 4 uM on granulocytes stimulated with PMA, IC(50) is 0. 51 uM on HL-60 cells undifferentiated and IC(50) is 0. 53 uM on HL-60 cells treated with DMSO).  The C-terminal peptide shows a higher bradykinin potentiating activity than the complete peptide.
What are the official names of this protein?
Bradykinin-potentiating peptide NDBP6, BPP-6.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AHL26_ARATH
Sequence: MDPVQSHGSQSSLPPPFHARDFQLHLQQQQQHQQQHQQQQQQQFFLHHHQQPQRNLDQDHEQQGGSILNRSIKMDREETSDNMDNIANTNSGSEGKEMSLHGGEGGSGGGGSGEQMTRRPRGRPAGSKNKPKAPIIITRDSANALRTHVMEIGDGCDIVDCMATFARRRQRGVCVMSGTGSVTNVTIRQPGSPPGSVVSLHGRFEILSLSGSFLPPPAPPAATGLSVYLAGGQGQVVGGSVVGPLLCSGPVVVMAASFSNAAYERLPLEEDEMQTPVQGGGGGGGGGGGMGSPPMMGQQQAMAAMAAAQGLPPNLLGSVQLPPPQQNDQQYWSTGRPPY
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 26.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y258_PYRAB
Sequence: MTRRIKTGIPGMDDILHGGIPERNVVLLSGGPGTGKTIFSQQFLWNGLQMGEPGIYVALEEHPVQVRQNMAQFGWDVRKYEEEGMFAMVDAFTAGIGKSKEYEKYIVHDLTDIREFIEVLRQAIRDINAKRVVVDSVTTLYINKPALARSIILQLKRVLAGTGCTSIFVSQISVGERGFGGPGVEHGVDGIIRLDLDEIDGELKRSLIVWKMRGTSHSMRRHPFEITDKGIVVYPDRVLKRGKILEL
What are the official names of this protein?
UPF0273 protein PYRAB02580.
What is the protein family that this protein belongs to?
Belongs to the UPF0273 family.
Protein: SFAS1_STRFR
Sequence: MRRTTRARTGLSALLLAASLGLGAAPAGADAPQRPAPTPASDSAAALHALDAAVERTLGDDSAGTYVDAGTGELVVTVTTEAAAAKVRAAGATPRRVQRGAAELDAAMAALEARAKIPGTSWGLDPRTNRIAVEADSSVSARDLARLRKVAASLDGAVSVTRVPGVFQREVAGGDAIYGGGSRCSAAFNVTKNGVRYFLTAGHCTNLSSTWSSTSGGTSIGVREGTSFPTNDYGIVRYTTTTNVDGRVNLYNGGYQDIASAADAVVGQAIKKSGSTTKVTSGTVSAVNVTVNYSDGPVYGMVRTTACSAGGDSGGAHFAGSVALGIHSGSSGCTGTNGSAIHQPVREALSAYGVNVY
What is the function of this protein?
Serine protease that preferentially cleaves peptide bonds on the C-terminal side of aspartate and glutamate with a 10-fold higher reactivity for a glutamyl bond than an aspartyl bond.
What are the official names of this protein?
Serine protease 1, Glutamic acid-specific protease, SFase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LGT_GLOVI
Sequence: MPMETGFTSPGPLIVQIGGFAVRWYSLLILAGIIAGTLLSQKLAPERKVAPEVLSDLVVWLVVGAIPMARLYYVLFEWQRFAGEPWWKVFAIWEGGIAIHGAILGGLLAGWLFCRRNGYSLLTMIDLAAPGLILGQAIGRWGNFFNSEAYGAPTNLPWKLFIPEANRPPGMAAFAYYHPTFLYESLWNLGVLALLLFVFFRFKNLRPGSIACLYALAYSVGRFWIEGLRLDSLMVGPLRTAQLVSLAGIVLGAVGLWWLNRRSARQEAP
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL33_SYNC1
Sequence: MADIITLACTECKQRNYTTTKNKKTKPERLEFNKYCRFCRKHTPHRETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: C170_GIAIN
Sequence: TNPSDPTGTCVSAVDCQGSAGYYTDDSVSDAKECKKCNAPCTACAGTADKCTKCDANGAAPYLKKTNPSDPTGTCVSAVDCQGSAGYYTDDSVSDAKECKKCNAPCTACAGTADKCTKCDANGAAPYLKKTNPSDPTGTCVSAVDCQGSAGYYTDDSVSDAKECKKCAEGQKPNTAGTQCFSCSDANCERCDQNDVCARCSTGAPPENGKCPAATPGCHSSCDGCTENAMTNQADKCTGCKEGRYLKPESAAGQSGACLTAEECTSDKTHFTREKAGDSKGMCLSCSDATHGITGCKKCALKTLSGEAESTVVCSECTDKRLTPSGNA
What are the official names of this protein?
Surface antigen CRP170.
Protein: ANR45_MOUSE
Sequence: MEPEETLESESSEKSLFSSQQEYEESQEAEETGAENPLLQPTLTGDVEGLQKIFEDPEHPHHEHAVQLLLEEDIVGRNLLYAACMAGKSDVIKALAKYGVNLNEATARGYTLLHCAAAWGRLETLKALVELDVDIEALNFRGEKARDVAARYSQVECVNFLDWADARLILKKIITKSSLIITDPEKGPGKLFKEDKSTILNACRLKNEWLESHPEASISEIFEQKQQLEDIVSPILAKMSTPRHFAAS
What is the function of this protein?
May play a role during cell division.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 45.
What are the subcellular locations of this protein?
Cytoplasm. Midbody, Midbody ring. Cleavage furrow. Note=Distribution is highly dynamic during mitosis. Not detected during interphase, localized to cytoplasm during metaphase, to cleavage furrow during anaphase and telophase, and to midbody ring during cytokinesis.
Protein: O163_CONAJ
Sequence: MKLTCLMIVAVLFLTAWTFVTAVPDSSNALENLYLKAHHEMNNPEDSELNKRCYDGGTSCNTGNQCCSGWCIFLCL
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like Ai6.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: P49_ASFP4
Sequence: MYHDYASKLLADYRSDPPLWESDLPRHNRYSDNILNSRYCGNKNGAAPVYNEYTNSPGQAEKGLQLSDLRNFSFMLNPQHKNIGYGDAQDLEPYSSIPKNKLFNHFKNYRPAFSTHTENLIKRNVVRTEKKTFPQVSGLKDTQKNCLTQPSSLPSLKNPKNSSVPSTRFSEHTKFFSYEDLPKLRTKGTIKHEQHLGDQMPGQCYNGYIPHQDVYNILCLAHKLPASVEKEIAGRGIPLGNPHVKPNIEQELIKSTSTYTGVPILGPLPPKDSQHGREHQEFSANRHMLQVSNILHSVFANHSIKPQILEDIPVLNAQLASIKPVSPFLNKAYQTHYMENIVTLVPRFKSIANYSSPIPNYSKRNNGQAEYFDTSKQTISRHNNYIPKYTGGIGDSKLDSTFPKDFNASSVPLTSAEKDHSLRGDNSACCISSISPSL
What is the function of this protein?
Together with the penton and the other minor capsid proteins (M1249L, p17), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid (By similarity).  Plays an essential role in the formation of infectious virus particles.  Especially required for the formation of the capsid vertices (By similarity).  During virion assembly, associates with the membrane and probably mediates the docking of the penton complex to the inner membrane, where it recruits the capsomers to form the penton core (By similarity).
What are the official names of this protein?
Minor capsid protein p49, p49.
What is the protein family that this protein belongs to?
Belongs to the asfivirus p49 structural protein family.
What are the subcellular locations of this protein?
Virion. Note=Localizes in close proximity to the capsid vertices.
Protein: PGK_LATSS
Sequence: MAKQTVADLKDIKGKKVLVRVDFNVPIKGGVIGDDNRIVAALPTIQYIIDNGGKAILLSHLGRIKSDEDKKELTLKPVAARLGELLNKDVAFVASNEGQELEDAINAMTDGQVLVMENTRFQDIDNDFGKRESKNDPKLGEYWASLGDMFVNDAFGTAHRAHASNVGIATAMKANNKPAVAGYLLEKEIKFLGEAVDAPERPFVAILGGAKVSDKIGVIEHLLAKADKVIVGGGMTYTFYAAKGLSIGNSLVEEDKIELAKELIEKAGDKLVLPVDNVVADAFSNDAKTETVEGNIPDGYMALDIGPKAIADFENVLKDAKTVVWNGPMGVFEMDNFAKGTLAIGEFLGNLSGATTIVGGGDSTAAVKKLGVGDKLTHISTGGGASLEYLEGKTLPGIAAISDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_SALPA
Sequence: MTQAVMLQGTASDVGKSVLVAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRAQIFQAEAAGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAVSYHDYKPRLREQILAVYNSLAQEYDVIVLEGAGSPAEINLRDRDIVNMGMAEMAQCPVILVADIDRGGVFAAIYGTLALLHKQERDRVKGVIINKFRGDVALLYSGIEQIESLTGVPVLGVMPWLDVDLEDEDGVALQNDKYRGNAPRDITIAIVQLPHISNFTDFNALAAQPDVRIRYIRRPEALTDADLVILPGSKNTLSDLAWLRESGMADAVLQTHRQGVPVMGICGGYQMLGDTIVDEVESGLGTQPGLGLLNTITRFAQDKTTTQVNATMSGELPGWLAAAAGLPVRGYEIHMGETVLQEGCCTAMTLQKNGCSVADGAVTADGLAFGTYLHGLFDSDAFTRAVVNGLRARKGLAPWETTFCYAEHKARQFDLLAEAMRQHIDIDKIYTIMQQHQEPV
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: DZI1L_RAT
Sequence: MQYSVATADGLSGPPSGAYTLPTFKFQPRRESIDWRRISAVDVDRVARELDVATLQENIAGVTFCNLDREVCNHCRQPVDPVLLKVLRLAQLIIEYLLHCQDCLSASVAQLEARLQASLGQQQRGQQELGRQADELKGVREESRRRRKMISTLQQLLLQTGAHSYHTCHLCDKTFMNATFLRGHIQRRHAGMAEVGKQKQEQQLGEVLEELRAKLKWTQGELEAQREAERQRQAQELEMIRQREIEAKKKFDEWKEKERSKLYGEIDKLKQLFWDEFKTVANQNSTLEEKLKVLQSYSMTESHLGSLRDEESEERLKHAQELQALREKMDIQKTEWKRKMKALHEERAAERRQLQEENERLHVTLSQDQKKAAAQSQRHINALRAQLQEQARLIESQEETIQTLSFRRMEEVQEVPKAVVTEEDSSEEELEASLEEQQEQRKVLAALRNNPAWLKQFRPILEDTLEEKLEGMGIKRGTKGISAQTVRRLEPLLRTQREQTARSFREFLSLREKLNQEVSSRAKKRWEGTAVVPQPDGQPPVKSQRTTLATREVRPKTRTLTVALPSKPAEPSTSTPRGHSSHGPGLTQVSTPIPRPRVHGPSSTPVSPGPGLSTPPFSSEEEPEGDVVQRVSLQPPKVLPRSAPQPEDNWGWSDSETSEESAQSPGKGSDGLASSATLVQSMVKNLEKQLETPAKKPSGGVNMFLRPNTALQRSSTPARKTQLSEDESDLEISSLEDLSHDLGPKGKPTPLSHSKLPEKFDASPWSSGSRPRIPGW
What is the function of this protein?
Involved in primary cilium formation.  Probably acts as a transition zone protein required for localization of PKD1/PC1 and PKD2/PC2 to the ciliary membrane.
What are the official names of this protein?
Cilium assembly protein DZIP1L, DAZ-interacting zinc finger protein 1-like.
What is the protein family that this protein belongs to?
Belongs to the DZIP C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes to centrioles and to the distal ends of basal bodies.
Protein: PPK5_PERAU
Sequence: GGGGSGETSGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5, FXPRL-amide, PerAu-Capa-PK.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADC_DICDI
Sequence: MEISQLLPKFKIEKIIKEWLEEDIPSFDYGGCVVGSDEKVAHLLGKQNGVFSGSIFFQEIFNQLGCKVIWFIKDGESFSMTHGPEKNKPQVLAHVIGPVRNILIGERLSLNILSRSCGITTQGYNVKKLVDGDNEQQQQQPWKGKIAGTRKTTPGFRLVEKLALLTAGLDTHRMDLSSMIMLKDNHIWACGNITNTVKNARSVGGFSLKIEVECRNQNEAIEAIEAGADIVMLDNFNPQDLQTVSTYLKQHYPHITLEASGGITSATIIQYAIPTIDIISMGNLTQGVPHIDISLKIQKQ
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: RNH2_XANOM
Sequence: MKILAANAQADSSNTEARQSLLFSQSPIPNAESRLLVAGVDEAGRGPLAGPVAVAAVVFDPNKPRINGLDDSKQLTAERREQLYARIVDRALAWSVVLIDSEEIDRINIYQATMLGMRRAVEGVAHVAGFARIDGNRVPKGLPCPAEALIGGDALDRAIMAASIVAKVTRDRLMHELHAQHPEYRFDQHKGYSTPMHLAALQTHGPCPQHRRSFAPVRLALEGREQGSAAIGDPEQLQVAQLVAPL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEP_I02A1
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRVGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RL4_NITWN
Sequence: MELNVTTLEGKAAGSVHLSDGIFGLEPRKDLIQRCVNWQLAKSQAGTHKTKGRAEIWRTGKKLFKQKGTGNARHGSARAPQFRGGGRAFGPVVRSHAHDLPKKVRALALRHALSAKAKDGGLIVIDSVELKEAKTKALMGHFSSLGLTSALIIDGAQVHAGFATAARNIPNIDVLPIQGINVYDILRRQKLVLTKAAVDALEARFK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SAMP2_PYRFU
Sequence: MKMIKVKVIGRNIEKEIEWREGMKVRDILRAVGFNTESAIAKVNGKVVLEDDEVKDGDFVEVIPVVSGG
What is the function of this protein?
Functions as a protein modifier covalently attached to lysine residues of substrate proteins, as well as a sulfur carrier in tRNA thiolation.  The protein modification process is termed sampylation and involves the formation of an isopeptide bond between the SAMP2 C-terminal glycine carboxylate and the epsilon-amino group of lysine residues on target proteins.  Is able to form polymeric chains with itself likely at Lys-55, similar to ubiquitin and other ubiquitin-like proteins.  May serve as a proteolytic signal in the cell to target proteins for degradation by proteasomes.
What are the official names of this protein?
Small archaeal modifier protein 2, SAMP2, Ubiquitin-like small archaeal modifier protein 2.
Protein: RS3_TROW8
Sequence: MGQKINPYGLRLGITTDHVSHWYSDSTRPGQRYADYVSEDIKIRSYLTKTLDRAGIARIEIERTRDRIRVDIYTARPGIVIGRRGAEADRYRLELEKITSKQVQLNILEVKNPETTARLVAQGIAEQLAARVAFRRAMRKGLQSATSAGVRGIRIRLAGRLGGAEISRSEFYIEGQVPLQTLRASIDYGFYEARTPYGHIGVKVWIYKKPSVRGRTEGGG
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: HIS4_NEUCR
Sequence: MTRFRPCIDLHAGQVKQIVGGTLDSATSELRTNFVSPHPPAYFAKLYRDNDLSGAHVIMLGPGNKEAALESLKAWPGGLQVGGGITDANAREWVEAGAEKVIITSYLFPNGKFSQSHLDAVLAALDGDKSKLVIDLSCRRQGDDRWFVAMNKWQTITDMEVSEESIKALEPYCSEFLIHAADNEGLQKGIDEKLVQRLSEWCSIPVTYAGGGRNLEDLETVKRLSGGKVDLTIGSALDCFGGKGVTLQECVEWNRRQ
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, 5-proFAR isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_STRA5
Sequence: MKLKETLNLGQTAFPMRAGLPNKEPQWQEAWDQADIYKKRQALNEGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRSKSMSGFRAPYVPGWDTHGLPIEQVLAKKGVKRKEMDLAEYLEMCRDYALSQVDKQRDDFKRLGVSADWENPYITLTPDYEADQVRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANKVKDGKGILDTDTYIVVWTTTPFTVTASRGLTVGPDMEYVVVVPVGSERKYLLAEVLVDSLAAKFGWENFEIVTHHTGKELNHIVTEHPWDTEVEELVILGDHVTTDSGTGIVHTAPGFGEDDYNVGIANGLDVVVTVDSRGLMMENAGPDFEGQFYDKVTPLVKEKLGDLLLASEVINHSYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKTNFQPEWGKKRLYNMIRDRGDWVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFAEYGSIVWWQRDAKDLLPAGYTHPGSPNGLFEKETDIMDVWFDSGSSWNGVMNARENLSYPADLYLEGSDQYRGWFNSSLITSVAVNGHAPYKAVLSQGFVLDGKGEKMSKSLGNTILPSDVEKQFGAEILRLWVTSVDSSNDVRISMDILKQTSETYRKIRNTLRFLIANTSDFNPKQDAVAYENLGAVDRYMTIKFNQVVDTINKAYAAYDFMAIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSPERRRMQTVFYDILVKLTKLLTPILPHTAEEIWSYLEHEEEEFVQLAEMPVAQTFSGQEEILEEWSAFMTLRTQAQKALEEARNAKVIGKSLEAHLTIYASQEVKTLLTALNSDIALLMIVSQLTIADEADKPADSVSFEGVAFTVEHAEGEVCERSRRIDPTTKMRSYGVAVCDASAAIIEQYYPEAVAQGFEA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_THEP3
Sequence: MRMIIKNGTVIDGFGSEATADILIDYGIIKAIDKNIQVSDGIVIDATGKYVLPGFVDMHTHLRQPGFEEKETIKTGTEAAATGGYTTVACMPNTNPPIDNEIVVEYVKSIAQREGVVKVLPIGAMTKGMKGEEITEMAKLKKAGVVALSDDGFPIMSAGLMKRIMTYGKMYDLLMITHCEDKALSGEGVMNSGVISTMIGLKGIPREAEEVMLARNIILAKSTGVRLHIAHISTKGSVELIREAKEKGVKITAEVTPHNLTLTDEAVYNYDTNTKAYPPLRTREDIEALIEGLKDGTIDAIATDHAPHTKDDKKVPYDMAAFGISGLETAFSVINTFLVQTGKITIKELVNYMSINPAKILGISSGIKVGSIADIVIVDPYEEYVVDKDKFKSKGKNTPFHGMRLKGVVDCTIVEGEIKYKKDRKTEKVEV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: UVRB_CHLCH
Sequence: MENRTDNEYQLVSPYQPAGDQPKAIEALVQGVRDGRHWQTLLGVTGSGKTFTISNVIAQLNRPVLVMSHNKTLAAQLYGELKQFFPHNAVEYFISYYDFYQPEAYLPSLDKYIAKDLRINDEIERLRLRATSALLSGRKDVIVVSSVSCIYGLGSPEEWKAQIIKLRAGMEKDRDEFLRELISLHYLRDDVQPTSGRFRVRGDTIDLVPAHEELALRIEFFGSEIESLQTFDIQTGEILGDDEYAFIYPARQFVADEEKLQVAMLAIENELAGRLNLLRSENRFVEARRLEERTRYDLEMMKELGYCSGIENYSRHISGRPAGERPICLLDYFPEDYMVVVDESHVTLPQIRGMYGGDRSRKTVLVEHGFRLPSALDNRPLRFEEYEEMVPQVICISATPGEHELMRSGGEVVELLVRPTGLLDPPVEVRPVKGQIDNLLAEIRHHISIGHKALVMTLTKRMSEDLHDFFRKAGIRCRYLHSEIKSLERMQILRELRAGDIDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRNTRSLMQIAGRAARNLDGFVVLYADVITRSIQEVLDETARRRAIQQRYNEEHGITPRSIVKSVDQILDTTGVADAEERYRRRRFGLEPKPERVLSGYADNLTPEKGYAIVEGLRLEMQEAAEHMEYEKAAYLRDEITKMEQVLKKDG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2449_CORGB
Sequence: MNRSTISPVEARQQFRAGLIQPTSGWSAGFAQANLISMPQDLAYDFLLFAQRNPKPCPILEVLNAGETFGGIFGSNATEADIRTDAPQYRIYEHGELIDSPASAVDYWRDDLVSFIIGCSFTFEHPMVQAGVPVRHLEAGRNVPMYETSLACRPAGSLSGNLVVSLRMIPASQVADAVRITSRYPAVHGAPVHIGDPSLIGIDDINNPDFGDAPLSEPGDVPVFWACGVTPQAMVMSSKPPLAITHAPGHMLITDAPDLGFQVP
What are the official names of this protein?
Putative hydro-lyase cgR_2449.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: EFTS_SOLM1
Sequence: MSAISAASVKALRDKTGAGMMDCKKALGECNGDEEKAVAWLREKGLSKAQKRAGRATSEGVIGSYIHSNGKLGVMVEIKCETDFVARSERFLEFAKNVAMQIAAANPVCVTPEEVPADLLAKEREIFKNQAMEEGKPEAIAEKIVDGRVKKLYKEICLLEQPFIKDDKVTIKDLMNELVGVIGENVQIGRFSRMALGEDA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.