PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_BORA1
Sequence: MSTQGFLKPRSIEVEPVGPNHAKIVMEPFERGYGHTLGNALRRILLSSMTGYAPTEVQMTGVVHEYSTIPGVREDVVDILLNLKGVVFKLHNRDEVTLILRKNGSGLVLASDIELPHDVEIVNPEHPICNLTDAGKLEMQIKVEKGRGYVPGNVRALSEDRTHTIGRIILDASFSPVRRVSYAVESARVEQRTDLDKLVLDIETNGVISPEEAVRQSARILMDQISVFAALEGAGDSYEAPVRGTPQIDPVLLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLAARGLTLGMKLENWPPLGLERP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: NTE1_DEBHA
Sequence: MSTIEIVSTVAEYTEIHSPVSSKFLLPSARDSSSSISLFSAIFWFWSWLFFKIMNIFLYYIPNIIVNLFSVNFQITLSLSSIVITLTGIISFCFLIVRYKYLTRYSKTTKSTDKPKSSNKNIDLVGSIKKNKRGDSKSTSNYLDEFLSAIKVFGYLERPVFHELTRNMTTQKLSSEEILYLDEKLGFSIVVEGTIQVYTKVNSVNSSTTSNSDDNELNFEKDDLLTIGDQCYQLLNEVKSGSPLSSLMSTLDLFKPVDPDTMSNRLFSPFELDSNPASNPLSPDNTGSKSFDPLSSGNFNDTSLSSSDRNYPNIVARPKPIEDSNNLNTATIAIIPYSAFQKVQSKYPKATSHIVTMVITRLYKITMNTIHSYLGLTREIIRSEIQLNESEGAKDSLPSYLYDGVIEKFYGDKNNETLLNKTAESPSVSINKTSSSSSSLPKKSTTSLRPLNRNQSSRYVVLDSRSKSTHPGDLLSSVPLSRRSDYYQTHTTIQPDPEEVRSQSRTKMTSPVLPKRQISSNGGPTLKGHSSSTTKFENIRDRTFSDEREETEETSLRIAIIENIFKILGINEVSNMIGSMSDLNSRSSSVNSSVVGLPSLMNNGNESKYPNGIFDFNTGKVRYDSISSFPTSLNKGANNNLKFYDTVNQSQLKDMDHENDKSSQVDINNLMFKRKSIPIQSFESNFYDVKNEFSKHLNIKYFGPNTTLVEQESFNSGLYYVIDGTLDVFYKPASKESENLTPMNKKKLYTVKSGGLAGYLSSIIGVRSLVSISTPGDKGVIVAHIPKNEFSKLLDKFYFLQLPVASKLKSLLSSQILTIDYALEWCHIPAGDVLCSQGDLANGFHIVLSGRFRVVRYNNNKSSEVNPDDNTDIHDYNNNLIDESLSYKSRKKKDDITILGEYGHGETIGEVEVLTASRRTNSLIAVRDSETARIPRTLFEMLSLRNPSIMVKVSRIVANKMAKKDNIGIPSTISSNVPLIVTNTDSHISNDYKTITILPTVSGLPVRDFADKLVSALKNIGRNVIALDQASTLTHLGRHAFDERLAQLKLSGYFAYLEEEYQTIVYVCDTPLKSNWTSTCISQGDCILLLADADDDDVATNIGEYERLLMKLKTTARTDLCLIHADKYVEPGSTSVWLKNRIWVQGHHHIQMEIARDNSVQQGQKTSIIKNIAAKISSRTNTNIKSRLENVKTKAILSLNKFNNRLSRRTHSYKTVQAHKNDFLRLARILSNESVGLVLGGGGSRGISHVGVVMALEKHGIPIDLIGGTSIGSFVGGLYAKDYNIVSIYGRAKRFAKRVSSWWRMVLDLTYPVTSYITGYEFNRGIWKIFGSSEIEDFWIRYFCNSTNITNSTMDIHESGFSWRFIRASMSLAGLLPPITYGGSMLLDGGYLDNLPVMEMKKKGAKYIIAVDVGSVDDRTPMNYGDTLSGFWVLFNRWNPFSRHPNVPNMMDIQLRLAYVASVNALELAKKTPGVIYLRPPIDDYATLDFAKFDEIYHVGMAYADNLLTRWEQTGKIPPIAGMIDRSRIRNGEERKSLYRRSSI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase NTE1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CLINK_FBNY1
Sequence: MGLKYFSHLPEELREKIVHDHLQQERKKEFLEKAIEDSCRRHVSLLKSDPSPSEMYSLSKFLDSLADYVGRQFNTRCLIKWRKDVPANIKFQVMEEQHLRLYGFLDMDDLSCRELLPPEEDDDITYEDGMIVNCSELDKLFAALGIRVVYITVSNNCICTPLNKDIVIS
What is the function of this protein?
Interacts with and disrupts the function of host retinoblastoma-related proteins RBR, which are key regulators of the cell cycle.  Induces transcriptional activation of E2F-regulated S-phase and G2/M-phase-specific genes.  Inactivation of the ability of RBR to arrest the cell cycle leads to the stimulation of viral DNA replication.
What are the official names of this protein?
Cell cycle link protein, Clink.
What is the protein family that this protein belongs to?
Belongs to the nanovirus Clink protein family.
Protein: GSLG1_CAEEL
Sequence: MWRFPLILASVCWLTTAQQQNVANDPDKKLASFDACKADIHKHCSRPDVDLTSDMSILECLQDAGFSETATLSEQCEQLVWDFKVKITQDERFVSAAKQYCEEELKGNAAMNLCTSQTQPGFALSCLMEFTKNVTETGKCHAFLARTERLAFSDFRLVGPFVTKCRAILDKFKCNVLTPDPAHKGVRVAHTQGMALECILDKVVKNAKTQADALQILGDDCKHEVLRLAEMQADDFHLDRPLFFACRLDRERYCKDVPSGEGKVFECLMMNRNDKFMDPECGNLLAERAYLMGRDYRMAHPLTKACQPELTRYKCEPQNQIESAAHFHLAWILLCLENGANQPEHKEVQPSKECAHEMITHRQMMMQHFRMAPELVLNCAQEIDKWCSPRGDIEAEGRTLHCLMEHAESRNETLKLGAQCLQAVQQVVKVADIGRNYKVDKVLYGSCRSLIDGPCAQDAVSETATLTCLMRNVDSPDMVPECEKRLLEVQYFMARDWTMDPQLYEACHQEAVSRCSALDNWHQQHNSDNTVDRGPQVLACLYRSAYDEQNPLSVKCGTQVRQLLHVRAVRVNLIPEIEDSCREALSEFCSHNVKPSEEMMCLQQNFETDNFKRKHPQCFAELTKFTEMEAKDTKLNRALSKACKPVISTHCAQFANEEIDHGDVLECLVNNKDAKEMNNKCRSYVNHFELISLRDYHFSYKFQKACASDIEQSCKGHNNDKGEIIRCLSEVRFEHKVLGSPKDLTDDCKKQLKVAYLQQEQVEFDDKEHMADADPKLSQKCEQEIKMYKCNQADTFEDTIECLRLNFEHLGPECKSMIFYREKIEAVDNSMDDELQKKCRYDIGKFCANSDSENVLECLTNTKIVRLLQRECKAIVKERMQESARDVRLRPQLLTSCRKEAEQYCPEDMKKINMPQYSQTVLDGVVVSCLRDKFRQSISDQNHIDFSPRCSAEVSRAIVEAEFDPQLDPPLYNACKSTINDHCSATIMESGGHFDNVMECLKNDFNKGLIRDKQCSEQVARRLQESLVDIHLDPVLHEACAMDIQRYCRDVPPGHSRIVMCLMDSADKQELSKECSTKLSDRNKLWMKAHSEFQMALPDSWHAFANLVMEHPERNSILGYLAGFIVFILLIGCCCGRVSKKQYIEMKNR
What are the official names of this protein?
Golgi apparatus protein 1 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SYR_MESH7
Sequence: MKKKISQAIIKFFKNENLIIDESKLIIEKSKNFGDYSSNVALMFAKQNKIDSLKLAQTIKNQLLSENLNLEKIEIAPPGFINFFISKNEYANIVSEIIQKGENFGRYSLQKKINLEFVSANPTGFLHLGHLRGAVIGDILANILEFSGNFVFREYYINDFGSQIDRLVSSVFSRYQQIFKKFALPEEAYLGEDIIWCAQKFFQIYANKFENSSLDDLETYKIFREKSIEIFLDEIKADLANLSIKFDVFSSESELFRTEKVQKNLANLPFVYKKEEAIWLKTSKFGDQKDRVLVKKNGEFTYFSSDIAYHFEKINSNFKPDFLINIWGADHIGYVDRMKAALKTVNLNQKLDILLYQLVKLFKNGQEFKMSKRMGKTFTIKDLLELVDQDAIRYFISERSYNSLVEFDIGLAAKISLQNPLFLIQYAHARASKLLANSTIVPEKILKFEAENETILISKLKQFEEIVLKITKNYKINLLNKYLLELANLFNSFYSNSKIIGNQNQNSLLSLTKAVQIVLKNGLKLLGIKAKERI
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_PELUB
Sequence: MSIKKDGIMVILSSPSGAGKTTLVKLLSKNKNFHISISHTTRKPRLNEIADKDYYFVDHDKFENLIKNEEFLEYAKVFNHLYGTTRTPVIEKLEKGENVIFDIDWQGADQIKNKKLNYKLITFFILPPSKEILFERLSNRDMKDKLIVEERMKEFSRDVLHWINYDYVIINDDLEECYSKISSLIDAEINNGSKDYDKDFIRKHVEKLTS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_SCHPO
Sequence: MPVESEHFETLQLHAGQEPDAATSSRAVPIYATTSYVFRDCDHGGRLFGLQEPGYIYSRMMNPTADVFEKRIAALEHGAAAIATSSGTSALFMALTTLAKAGDNIVSTSYLYGGTYNLFKVTLPRLGITTKFVNGDDPNDLAAQIDENTKAVYVESIGNPMYNVPDFERIAEVAHAAGVPLMVDNTFGGGGYLVRPIDHGADIVTHSATKWIGGHGTTIGGVIVDSGKFDWKKNSKRFPEFNEPHPGYHGMVFTETFGNLAYAFACRTQTLRDVGGNANPFGVFLLLQGLETLSLRMERHVQNAFALAKYLEKHPKVNWVSYPGLESHVSHKLAKKYLKNGYGAVLSFGAKGGPDQSRKVVNALKLASQLANVGDAKTLVIAPAYTTHLQLTDEEQISAGVTKDLIRVAVGIEHIDDIIADFAQALEVA
What is the function of this protein?
Catalyzes the conversion of O-acetyl-L-homoserine (OAH) into homocysteine in the methionine biosynthesis pathway (PubMed:11754480, PubMed:6526818).  Can also use O-succinyl-L-homoserine and L-homoserine as substrates (PubMed:6526818).  Has also cysteine synthase (O-acetylserine sulfhydrylase) activity in vitro, but in S. pombe, it seems only to be involved in the alternative pathway of methionine biosynthesis under cysteine deficiency conditions (PubMed:11754480).
What are the official names of this protein?
Homocysteine synthase, O-acetylhomoserine sulfhydrylase, OAH SHL, OAH sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SPT5_PYRFU
Sequence: MAGKIFAVRVTHGQEETTAKLIYSKVRTYNLPIYAILAPSRVKGYIFVEAPNKGVVDEAIRGIRHARGVLPGEVPFKEIEHFLEEKPAVSGLEPGDLVEVIAGPFKGQKAKVVKIDESKDEVVVQFIDAIVPIPVTIKGDYVRLISKLQKEE
What is the function of this protein?
Stimulates transcription elongation.
What are the official names of this protein?
Transcription elongation factor Spt5.
What is the protein family that this protein belongs to?
Belongs to the archaeal Spt5 family.
Protein: TMM40_MOUSE
Sequence: MEASGSSSQSQDSGGVHRETEDHYQETELHKHHGKARERYKRDKSSSSSSSSSSSSSSSSSSSSSSSDSSDEDQPSRGPRKHRRRPRRDSLRGADHGELEVLKDELQLCGGAAGEMVPTGESGLRRRGSGSAEGEVEASQLRRLNIKKDDEFFHFVLLCFAIGALLVCYHYYADWFMSLGVGLLTFASLETIGIYFGLVYRIHSVLQGFIPLLQKFRLPGFRRTN
What are the official names of this protein?
Transmembrane protein 40.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: WALK_STAA2
Sequence: MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDNFKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIIIATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKVIGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTVEMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGIIATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDLNEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLTSMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEIIDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRGDKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGLAISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins.  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue in the dimerization domain and transfers its phosphate group to the conserved aspartic acid residue in the regulatory domain of WalR.  In turn, WalR binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression.
What are the official names of this protein?
Sensor protein kinase WalK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIGC1_MYCS2
Sequence: MDLPVQPPIEPMLAKAQVKVPDEAGVWSYEPKWDGFRALVFRDGDDVVLQSRNGKDLGRYFPELLDALRDELVEKCVLDGEVVVPRDIAGRVRLDWESLSQRIHPAASRIKMLAEQTPAHFIGFDALALGDRSLLKEPFRVRREALAEAVDNKRWCHVTRTSEDPALGTEWLKTFEGAGLDGVIAKRLDGPYLPGKREMVKVKHHRDADCVAMGYRIHKSGDGIGSILLGLYRDDGELQMVGGAASFTAKDRIKLLAELEPLREGDEMREGDPSRWNSAADKRWTPLRPEKVCEVAYDQMEGNSVEGRRFRHAVKFLRWRPDREPSSCTFDQLDTPLNYDLYDVLEEQ
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity).  Has weak intrinsic nick joining activities and accumulates DNA-adenylate.  Acts as a backup for LigD in the Ku-LigD-dependent NHEJ pathway.
What are the official names of this protein?
DNA ligase C1, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: HLDD_ESCF3
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: PIGZ_HUMAN
Sequence: MQICGSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGSTFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWLLGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVLLPGAALTAAVFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSPQTQPVPWKGTVVLFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVLPSTPTHYTLLFTHTYMPPRHLLHLPGLGAPVEVVDMGGTEDWALCQTLKSFTRQPACQVAGGPWLCRLFVVTPGTTRRAVEKCSFPFKNETLLFPHLTLEDPPALSSLLSGAWRDHLSLHIVELGEET
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers a fourth mannose to some trimannosyl-GPIs during GPI precursor assembly.  The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues.
What are the official names of this protein?
GPI mannosyltransferase 4, GPI mannosyltransferase IV, GPI-MT-IV, Phosphatidylinositol-glycan biosynthesis class Z protein, PIG-Z, SMP3 homolog, hSMP3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGZ subfamily.
Protein: FLIG_BUCAI
Sequence: MIVNGTEKSALLLMAIGSDQAGEILKHLTPFEVQELITAMVNIKRVSAQKLNEILLQCYNLAIKNNAFNCNNSDKYLIKMLTKALGEKKGTSLLKEALEIRNARICIKALNYMKAKQVAFLLDKEHPQIITTILICLNKNQSAEVLSFLSDKKRAEIILRIVDFHGIEESSLVELTQVINNLLKNKKLILSEKGGIKTAAQILNSMKIKHEKEIIENISKSNEQLADKIIKEIFLFENLVDLDDKYIKILLENIEKEKLHIALQNTSQAIREKFFKNMSHTESNELTLNLEKKSYISDISIKNEQKLILIMLKSIVENGRISLKNLREYYV
What is the function of this protein?
FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body.  This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).
What are the official names of this protein?
Flagellar motor switch protein FliG.
What is the protein family that this protein belongs to?
Belongs to the FliG family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Bacterial flagellum basal body.
Protein: RRF_THEFY
Sequence: MIEETLLEAEEKMEKAVLVTKEDFASIRTGRPSPATFSRITVEYYGAMTPVNQLASFQVPEPRMVIISPYDKAAMPAIEKAIRESDLGVNPSNDGNIIRVVFPELSEERRKEYVKVARNKAEDGRTSVRNVRRQAKDAIDKAVKAGEIGEDEGHRAQKELDALTQKYVGEIDELLKHKESELLEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_WIGBR
Sequence: MENIRNFSIIAHINHGKSTLSDRLIQICGNISNREMSNQILDTMDLERERGITIKAQSVRLNYKAKNKKNYQLNLIDTPGHADFSYEVSRSLSACEGALLIIDSSQGIEAQTIANFYCAIEMKIKIIPVLNKIDLPNSDPDKISKEIESMMGIKSKEIIKCSAKTGYGVYEILENIVCNLTPPIGNINKPLQALIIDSWFDNYLGIIVLIRIKNGNLKNGEKIIVMSTKKVYSIAQMGFFSPNKTKTDILKCGEVGWIACSIKEIKGAPVGDTITLASYPSEKMLPGFKKIFPKVFASIFPTISEKYQSLKNGLIKLSLNDSSLFYEYENSDSLGMGFRCGFLGLLHMDIVKERLEREYQIELIITEPTVIYEILKKDNTKIHVKSPSKIPNKKYINELREPIVNCKILSPKKYLGKIISLCVEKRGIQNNLIYLENKVIIIYIIPMSEIILDFFDKLQSISNGYASLDYKFKCFNKTDSVVIQTYINKKLIDSLTKVINKNYINLYSKKTIENLKKIIPRQQFDIVIHIKINNKIISKGIVKQVRKNVLEKCYGGDVSRKKKLLKKQKIGKKRMKKIGNFFLPQDSLFSILNIKKNKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: O16G_PARTM
Sequence: MERVWWKEAVVYQIYPRSFYDSNGDGIGDIRGIIAKLDYLKELGVDVVWLSPVYKSPNDDNGYDISDYRDIMDEFGTMADWKTMLEEMHKRGIKLVMDLVVNHTSDEHPWFIESRKSKDNPYRDYYIWRPGKNGKEPNNWESVFSGSAWEYDEMTGEYYLHLFSKKQPDLNWENPKVRREVYEMMKFWLDKGVDGFRMDVINMISKVPELPDGEPQSGKKYASGSRYYMNGPRVHEFLQEMNREVLSKYDIMTVGETPGVTPKEGILYTDPSRRELNMVFQFEHMDLDSGPGGKWDIRPWSLADLKKTMTKWQKELEGKGWNSLYLNNHDQPRAVSRFGDDGKYRVESAKMLATFLHMMQGTPYIYQGEEIGMTNVRFPSIEDYRDIETLNMYKERVEEYGEDPQEVMEKIYYKGRDNARTPMQWDDSENAGFTAGTPWIPVNPNYKEINVKAALEDPNSVFHYYKKLIQLRKQHDIIVYGTYDLILEDDPYIYRYTRTLGNEQLIVITNFSEKTPVFRLPDHIIYKTKELLISNYDVDEAEELKEIRLRPWEARVYKIRLP
What are the official names of this protein?
Oligo-1,6-glucosidase, Dextrin 6-alpha-D-glucanohydrolase, Oligosaccharide alpha-1,6-glucosidase, Sucrase-isomaltase, Isomaltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_MOOTA
Sequence: MKQPSLDELEKRAGSKYALAVLAAKRARMLTESQFAAQYPKGTKPVTIALMEIAAGKIKYEWGKKKA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: SYS_BIFA0
Sequence: MLDIQFIREHPEVVKESQRKRGESVELVDEVLRADEERRSSLKQFEEARARQKEIGKQVAKAAPDEKAKLIAQTKELSEQVASFKASADTADEQYTTAMWQLSNIVEPQAPEGGEDDYVVMRKVGQIRDFAAEGFEPKDHLTLGEEVAGIDMKRGVKVSGSRFYFLRGDVARLQIAMLTMAVDQAQEHGFILAITPTLVRPEVMRGTGFLNSHADEIYRLREPDDDYLVGTSEVALAGMHENEILDLSDGPLRYCGWSSCYRREAGAAGKDTSGIIRVHQFDKVEMFVYAKPENSDAEHQKLLAMEEEMLAKVEVPYRVIDTAAGDLGSSAARKFDCEAWVPTQGRYRELTSTSNCTQYQARRLNIRERVADGGTSPVATLNGTLATTRWLVAILENHQQADGSIEIPKAMRPYMGGKEVIEPRKWEA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_PROM2
Sequence: MKILYPGTFDPLTNGHIDLIERAEKIFGNLVVAVLENTSKTPTFNLQRRIIQIKNSLSHLPNIEVISYSGLTVDCANELKANLILRGLRAMSDFEYELQIAHTNKSLNNDIETIFLSTNTNYSFLSSSLVKEVAKFGGEINHMVPPSVERDLKEYFK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BIFA0
Sequence: MTDFSQIHKPVLLQECVDLVTPALHASDSVAVDCTLGLAGHTIAFLKAAPNATVIGIDRDEEALDKATARIAQEGLSARFVPVHAAFDQFDEVLRAQGVSRVQAVFMDLGLSSLQIDERERGFSYAHDAPLDMRMDTSQALTAREILATYDADRLAHIFKEYGEERFSKPIAKRIVQQRQSSPLETSSQLTALVDAVIPAARRGSGNPAKRVFQALRIEVNGELDKLRRTLPQIGLHLAVGGRLVVESYHSLEDRTVKNFMAQGLRVDAPADMPVIPPDMQPFFKALTKGAVKADAGEIAYNPRSASVRLRAVELTRPLPQRWVHAFELESQGSEDGVRGAHGHRRRTQARRG
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y633_GEOSM
Sequence: MPSFDIVSKVDMQEVDNAINQTVKEIAQRYDFKGSKCEVTLEKESIKVLADDDFKLKAVIDILQSKFVKRNISPKSLQYGKAEQASGSMVRQIITLQVGISKEKAKEIGQVIKETKLKVQSQIQDDQLRVTGKNIDDLQEVIRVLKGKDLDIDMQFVNFRS
What are the official names of this protein?
UPF0234 protein GM21_0633.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: LGT_ALIFM
Sequence: MSQGYLNFPHIDPVLIEIGPLAVRWYGLMYLFGFMFALWLANKRADKPNSGWTRDQVSDLLFAGFLGVVIGGRVGYVLFYNFGYFLDNPLYLFEVWTGGMSFHGGLLGVISAMLWYGYKNNRSFFTIADFVAPLVPFGLGAGRLGNFMNGELWGRVTDVPWAMVFPTGGPFPRHPSQLYEFALEGVVLFFILNWFIRKPRPLGAVSGLFLFGYGTFRFLVEYVRQPDAQLGLFGDWISMGQILSLPMVIGGLLMMLWAFKRNLFATDVEQNKTKSKKSKQKAK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GGT_ECOLI
Sequence: MIKPTFLRRVAIAALLSGSCFSAAAAPPAPPVSYGVEEDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDKYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTTHYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGLNVAEATNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYGASDPRSVDDLTAGY
What is the function of this protein?
Cleaves the gamma-glutamyl bond of periplasmic glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds.  The metabolism of glutathione releases free glutamate and the dipeptide cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases; it may function in amino acid uptake/salvage, or possibly in peptidoglycan linkage.  Catalyzes the hydrolysis and transpeptidation of many gamma-glutamyl compounds (including some D-gamma-glutamyl substrates), with a preference for basic and aromatic amino acids as acceptors (PubMed:2877974).  The KM values for gamma-glutamyl acceptors are so high that it has been proposed transpeptidation is not the physiological role in E. coli (PubMed:2877974, PubMed:8104180).
What are the official names of this protein?
Glutathione hydrolase proenzyme, Gamma-glutamyltranspeptidase proenzyme, GGT.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HTPX_HYPNA
Sequence: MGTAKTFTLLAAMTAIFMAIGFLVGGMAGMILAFVVAAGMNVFAWWNSDKMVLRMQGAQEVLPDTKNPMLRAFGEDVARLAENAGLPAPRIYIIDTPQPNAFATGRNPQNAAVAATTGLLNMLNREEVAGVMAHELAHVQNRDTLTMTVTATLAGAIGMLANFALFFGRDRAGLIGSIAIMIFAPMAAALVQMAISRSREYVADKRGAEICGNPLWLASALEKIERGARSQINPYAERSPAMAHMYISNPLNGRGQDKLFSTHPSTANRVEALRRMAGEMGISGVAAPTARSSGPWG
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.