PharMolix/UniProtQA huggingface dataset:
Protein: Y1250_MYCTO
Sequence: MTTAIRRAAGSSYFRNPWPALWAMMVGFFMIMLDSTVVAIANPTIMAQLRIGYATVVWVTSAYLLAYAVPMLVAGRLGDRFGPKNLYLIGLGVFTVASLGCGLSSGAGMLIAARVVQGVGAGLLTPQTLSTITRIFPAHRRGVALGAWGTVASVASLVGPLAGGALVDSMGWEWIFFVNVPVGVIGLILAAYLIPALPHHPHRFDWFGVGLSGAGMFLIVFGLQQGQSANWQPWIWAVIVGGIGFMSLFVYWQARNAREPLIPLEVFNDRNFSLSNLRIAIIAFAGTGMMLPVTFYAQAVCGLSPTHTAVLFAPTAIVGGVLAPFVGMIIDRSHPLCVLGFGFSVLAIAMTWLLCEMAPGTPIWRLVLPFIALGVAGAFVWSPLTVTATRNLRPHLAGASSGVFNAVRQLGAVLGSASMAAFMTSRIAAEMPGGVDALTGPAGQDATVLQLPEFVREPFAAAMSQSMLLPAFVALFGIVAALFLVDFTGAAVAKEPLPESDGDADDDDYVEYILRREPEEDCDTQPLRASRPAAAAASRSGAGGPLAVSWSTSAQGMPPGPPGRRAWQADTESTAPSAL
What are the official names of this protein?
Uncharacterized MFS-type transporter MT1289.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EmrB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCA_THISH
Sequence: MKTYLVGGAVRDELLGLPVRERDWVVVGATAAQMLDLGYRQVGRDFPVFLHPETHEEHALARTERKTAPGYRGFVVHAEPDVTLEEDLLRRDLTINAMARDEAGGLIDPFNGRADLEARLLRHVSPAFAEDPVRILRVARFAARFAHLGFRVADETRALMRRMVAAGEVDALVPERVWQEMERALGEGSPATFFEVLRDCGALAVLFPEIERLFGVPQPPKYHPEIDTGVHTLMVLTQAARLSADATIRFAALTHDLGKGTTPADILPSHHGHEQRSVDLVHALCDRFRIPNAYRDLAVMVARWHGYSHRALELRPDTVLKALEGLDAFRRPERFEPFLLACEADYRGRTGFEDRPYPQADYLRAAHARCLAISAKDLVNEGLTGKAIGEALHARRVQALKQLKAEWGG
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: ENGB_VIBPA
Sequence: MSVKIHYQNTHFITSAPDIRHLPEDEGVEIAFAGRSNAGKSSALNRLTNQKSLAKTSKTPGRTQLINLFKVEEGCHIVDLPGYGFAQVPVEMKNKWQKSLGEYLQKRECLKGLVVLMDIRHPMKDLDQQMIFWAIDSRIPVQVLLTKADKLKSGARKQTLLKIRKQVETFGGDVSVDVFSSLKGLGVDQLRAKLDTWFAPALAHLIEEDDLEMPESNEE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ASSY_BACAN
Sequence: MEKKKVVLAYSGGLDTSVAIKWLQEKNYDIIALCLDLGEGKDLAFVKEKALSVGAIKSYMIDVQEEFANEYALMAMQAHTLYEGKYPLVSALSRPLIAKKLVEIAEQEGATAVAHGCTGKGNDQVRFEVSIQALNPYLEVIAPVREWKWSREEEIAYAKENNVPIPINLDSPFSIDQNLWGRSNECGILEDPWAAPPEDAYEMTLALEDTPNKPEFVEIGFEAGVPTTLNGTAYPLSELIKTLNALAGKHGVGRIDHVENRLVGIKSREVYECPAAMTLITAHKELEDLTLVKEVAHFKPMIEQKITELIYNGLWFSPLKQALHAFLQETQKNVTGTVRVKLFKGHAIVEGRKSEYSLYDEKLATYTAQDEFNHDAAVGFISLFGLPTKVYSQVNQKKVEA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHF1_YEAS7
Sequence: MPKRLSGLQKEVLHLYRASIRTAHTKPKENQVNFVNYIHEEFGKYRNLPRKDFTTIEHLLRVGNKKIATFSHPELTNIH
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Promotes maturation of the iron-sulfur protein subunit SDH2 of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants.  Acts together with SDHAF3 (SDH7).
What are the official names of this protein?
Succinate dehydrogenase assembly factor 1, mitochondrial, SDH assembly factor 1, SDHAF1.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. SDHAF1 subfamily.
Protein: CAF1A_ARATH
Sequence: MNEIHQPLARRVWRSNVDEEMARMAECLKRFPLIAFDTEYPGIIFRTYFDSSSDECYRAMKGNVENTKLIQCGFTLFNAKGEIGGVWEINFSNFGDPSDTRNELSIEFLRRHGLDLQKIRDEGVDMFGYGFFPKLMTVFRSQKHVEFVTFQGAYDFAYFLSILNHGKLPETHGEFATEVVKVFGQVYDTKVMAGFCEGLGEHLGLSKLAQLLQITRVGRAHHAGSDSLMTALVFIKLKHVYEDSRFARGLIYGIGKSNLVAAPAPAPVPEPTLPLMCQQNVASYPVFHNGYVQNYEQPQLVSYDPSGAPWAFCNATGTYVQLTHLPASTFAYPSQTPSATVDYLGPVPNYYNNNACYVVE
What is the function of this protein?
Ubiquitous transcription factor required for a diverse set of processes.  It is a component of the CCR4 complex involved in the control of gene expression (By similarity).
What are the official names of this protein?
Probable CCR4-associated factor 1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the CAF1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ANX11_COLLI
Sequence: MAVVSEFLKQAWFMENLEQECIKCTQCVHGVPQQTNFDPSADVVALEKAMTAKGVDEATIIDIMTTRTNAQRPRIKAAYHKAKGKSLEEAMKRVLKSHLEDVVVALLKTPAQFDAEELRACMKGHGTDEDTLIEILASRNNKEIREACRYYKEVLKRDLTQDIISDTSGDFQKALVSLAKADRCENPHVNDELAEKDARALYEAGEQKKGTDINVFVTVLTARSYPHSEVFQKYTKYSKHDMNKAVDMEMKGDIEKCLTALVKCATSKPAFFAEKLHMAMKGFGTQHRDLIRIMVSRHEVDMNEIKGYYKKMYGISLCQAIMDELKGGYETILVALCGSDN
What is the function of this protein?
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.  This protein regulates phospholipase A2 activity.  It seems to bind from two to four calcium ions with high affinity.
What are the official names of this protein?
Annexin A1 isoform p35, Annexin I isoform p35, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Note=Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium. Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
Protein: YQGF_YERPY
Sequence: MANRTIIAFDFGTKSIGVAIGQEVTGTARALTAFKAQDGTPDWQQVEKLLKEWQPNLVVVGLPLNMDGTEQPLTARARRFANRLHGRFGVQVALQDERLSTVEARANLFDRGGYRALDKGSVDAASAVIILESWFDEQAG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5991_PSEA7
Sequence: MRIWIDADACPKAAKELVCKFALKRKLEVWMVAGQPQVKPPFACVRLVVVESGMDAADDYLVEQAEPGDLVICSDVPLADRLIKKQVAALDPRGREFDARNMGDKLAMRNLMADLRDLGQMGGGQAPYGDRDRQAFANALDRLLTRLQREAGLRANQPHK
What are the official names of this protein?
UPF0178 protein PSPA7_5991.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: RIR2_ASFP4
Sequence: MEELLIENSHRFTIFPIQHPECWNWYKKLESLTWTAQEVDMCKDIDDWEAMPKSQREFYKQILAFFVVADEIVIENLLTNFMREIKVKEVLYFYTMQAAQECVHSEAYSIQVKTLIPDEKEQQRIFSGIEKHPIIKKMAQWVRQWMDPTKNSLGERLVGFAAVEGILFQNHFVAIQFLKEQNIMPGLVSYNEFISRDEGVHCSFACFLISNYVYNIPEERIIHKILKEAVELVDEFINYAFDKARGRVPGFSKEMLFQYIRYFTDNLCFMMQCKSIYKVGNPFPQMTKFFLNEVEKTNFFELRPTQYQNCVKDDAFAFKLFLNDDDF
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: CYSD1_SHESH
Sequence: MSKHLTHLKQLEAESIQIMREVAAEFDNPVMLYSVGKDSSVLLHLARKAFYPGKIPFPLMHVDTNWKFKEMIEFRDQMAEKHGFDLIVHKNPRGIEMGISPFTHGSAKHTDIMKTEGLKQALDMHGFDAAFGGARRDEEKSRAKERVYSFRDSKHRWDPKNQRPELWNIYNGKVDKGESIRVFPLSNWTELDIWQYIYLEGIEIPSLYLAAERPVVERDGTLIMVDDERMPIESGEDVQTKMVRFRTLGCYPLTGAVESEAQTLPEIIQEMLLCTTSERQGRVIDNDSAGSMEKKKMEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2 1, ATP-sulfurylase small subunit 1, Sulfate adenylate transferase 1, SAT 1.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: PENQ_PENCR
Sequence: MDYVTQSPWIVTLIVAATTYCTLRWVQYWRSWVNVPVVGRRGFLGSWISTILWTWEARGCIQKGYEKNKDFAFQVSTPNGWEVCICNDDMIKEYKNLMDDQMSALAVTSETFQAKYTLPGADWDAVHKLVPQPALAKSLMWLRNRAANDTDPYFADFVKTFQRAFKEEIQVEQDGAPFPCFPRYSRIVAALTVKALLGSLENRPELIDLLCEYAEAIPLDGFFIALFPAVLKPIVAFFCKAPRLSDRLVKVITEEIARRELENKHRIPEDMTDWMAQWVKDNPGYCIESAVVRVIATFFGGIHTTTQLTVHTLLEIATRPEYVDPLRQEITTALKTHGGWNKSAIESMTKLDSFIKEAQRFNPLDAASLARQATRDFQFSNGLKLPRGTWVFAPNGPMLFDESLYPAGSQFDGLRFWKLAEQTQKPHDYRLVTASSKYLQFGDGRHTCPGRFMAADEIRLIVAHTLFHFDIAIKNHGPRPRNTTFKKICFPDMAAEIMLRPRKPHGSDGN
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes penitrems (PubMed:26213965).  The geranylgeranyl diphosphate (GGPP) synthase penG catalyzes the first step in penitrem biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (Probable).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase penC then forms 3-geranylgeranylindole (3-GGI) (Probable).  Epoxidation by the FAD-dependent monooxygenase penM leads to a epoxidized-GGI that is substrate of the terpene cyclase penB for cyclization to yield paspaline (Probable).  Paspaline is subsequently converted to 13-desoxypaxilline by the cytochrome P450 monooxygenase penP, the latter being then converted to paxilline by the cytochrome P450 monooxygenase penQ (PubMed:26213965).  Paxilline is converted to beta-paxitriol via C-10 ketoreduction by the short-chain dehydrogenase PC-15 which can be monoprenylated at the C-20 by the indole diterpene prenyltransferase penD (Probable).  A two-step elimination (acetylation and elimination) process performed by the O-acetyltransferase PC-16 and the P. simplicissimum ptmI-ortholog not yet identified in P. crustosum, leads to the production of the prenylated form of penijanthine (Probable).  The FAD-linked oxidoreductase ptmO then converts the prenylated form of penijanthine into PC-M5 which is in turn transformed into PC-M4 by the aromatic dimethylallyltransferase PC-22 (Probable).  A series of oxidation steps involving 4 cytochrome P450 monooxygenases (PC-21, PC-05, PC-23, PC-20) and a FAD-dependent monooxygenase (PC-14) are required for the transformation of PC-M4 to penitrems A and E.  Synthesis of these final products is proposed to proceed via penitrems D and C (PC-21, PC-05, PC-14) and penitrems B and F (PC-21, PC-05, PC-14, PC-23) (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase penQ, Penitrem biosynthesis cluster protein Q.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PLSY_SYNY3
Sequence: MTTALLLCLCLLLITYLMGSIPTGYLAGKLLLGIDIREHGSKSTGATNVFRTLGKPAAIAVLAIDISKGVMAVALVRAIYSGDWLPALPAAWQNWLTLGVAIAVVLGHSKSIFLKFSGGKSVATSLGVLFMLNIWLALGTLATFLTVIFFTRIVSLSSIVAAIAVNGIALALQLPPPYLAFTFLAGMYVIVRHRTNIERILQGTEPKLGEKVSSVPDRKGVA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AOFB_HUMAN
Sequence: MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
What is the function of this protein?
Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:11134050, PubMed:8665924, PubMed:8316221, PubMed:11049757, PubMed:20493079).  Preferentially degrades benzylamine and phenylethylamine (PubMed:11134050, PubMed:8665924, PubMed:8316221, PubMed:11049757, PubMed:20493079).
What are the official names of this protein?
Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAO-B.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: GCH1_BACPU
Sequence: VEAEHMCMTMRGVKKPGAKTVTSAVRGTFANVAAARAEVLSFIKND
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RSAD2_MOUSE
Sequence: MGMLVPTALAARLLSLFQQQLGSLWSGLAILFCWLRIALGWLDPGKEQPQVRGEPEDTQETQEDGNSTQPTTPVSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKQAGLEKINFSGGEPFLQDRGEYLGKLVRFCKEELALPSVSIVSNGSLIRERWFKDYGEYLDILAISCDSFDEQVNALIGRGQGKKNHVENLQKLRRWCRDYKVAFKINSVINRFNVDEDMNEHIKALSPVRWKVFQCLLIEGENSGEDALREAERFLISNEEFETFLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCTGGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYVWSKADLKLDW
What is the function of this protein?
Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon.  Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) via a SAM-dependent radical mechanism.  In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication.  Therefore, inhibits a wide range of DNA and RNA viruses (By similarity).  Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6.  Plays a role in CD4+ T-cells activation and differentiation.  Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities.  Can inhibit secretion of soluble proteins (By similarity) (PubMed:17686841, PubMed:19047684, PubMed:21435586, PubMed:21880757).
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2, SAND, Radical S-adenosyl methionine domain-containing protein 2, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible, Viperin.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RSAD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Endoplasmic reticulum. Lipid droplet. Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane.
Protein: DPOA2_BOVIN
Sequence: MAVSAQLLVEELQIFGLECEEAVIEKLVELCILYGQNEEGMASELIAFCTSTRKDCFTLETLNSFEHEFLSKRVSKTRHGASKDKGLRHAGARDIVSIQELIEVEEEEETLLNSYTTPSKGSQKRTITTPETPLTKRSVSARSPHQLLSPSSFSPSATPPQKYSSRSNRGEVVTSFGSAQGVSWSGRGGASPLSLKVLGHPEPLTGSYKYMFQKLPDIREVLTCKIEELGSELKEHYKIEAFAPILVPAQEPVTLLGQIGCDSNGKLNHKSVILEGDLEHSSGAQIPVDLSELKEYSLFPGQVVVMEGINTTGRKLVATRLYEGVPLPFHQPDEEDGDSEQFMVLVACGPYTTSDSITFDPLLDLITIINRDRPDVCILFGPFLDAKHEQVESCLLTSSFEDVFKQCLRTIIEGTRSSGSHLIIVPSLRDVHHEPVYPQPPFSCSDLLREDKKRVRLVSEPCTLSINGVIFGLTSTDLLFHMGAEEISSSSGTSDRFSRILRHILTQRSYYPLYPPQEDMAIDYENFYLYAQLPVTPDVFIAPSELRYFVKVGLNSAISLQCQNQFLSGALALNSSRVCWWGQWPRSFGGGVGVENKSVSIMLK
What is the function of this protein?
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (By similarity).  During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit POLA1, an accessory subunit POLA2 and two primase subunits, the catalytic subunit PRIM1 and the regulatory subunit PRIM2) is recruited to DNA at the replicative forks via direct interactions with MCM10 and WDHD1 (By similarity).  The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.  These primers are initially extended by the polymerase alpha catalytic subunit and subsequently transferred to polymerase delta and polymerase epsilon for processive synthesis on the lagging and leading strand, respectively (By similarity).
What are the official names of this protein?
DNA polymerase alpha subunit B, DNA polymerase alpha 70 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase alpha subunit B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPB_CAMJ8
Sequence: MQGFISQVLGPVVDVDFNDYLPQINEAIVVNFESEGKKHKLVLEVAAHLGDNRVRTIAMDMTDGLVRGLKAEALGAPISVPVGEKVLGRIFNVTGDLIDEGEEISFDKKWAIHRDPPAFEDQSTKSEIFETGIKVVDLLAPYAKGGKVGLFGGAGVGKTVIIMELIHNVAFKHSGYSVFAGVGERTREGNDLYNEMKESNVLDKVALCYGQMNEPPGARNRIALTGLTMAEYFRDEMGLDVLMFIDNIFRFSQSGSEMSALLGRIPSAVGYQPTLASEMGKFQERITSTKKGSITSVQAVYVPADDLTDPAPATVFAHLDATTVLNRAIAEKGIYPAVDPLDSTSRMLDPNIIGEEHYKVARGVQSVLQKYKDLQDIIAILGMDELSEEDKLVVERARKIEKFLSQPFFVAEVFTGSPGKYISLEDTIAGFKGILEGKYDHLPENAFYMVGNIDEAIAKADKLKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CUTA_SHIFL
Sequence: MLDEKSSNTTSVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLCR1_ARATH
Sequence: MPAMPGLVSVKTPSDTPPLRVAVPDTQPLSNPPRTPMKKTPSSTPSRSKPSPNRSTGKKDSPTVSSSTAAVIDVDDPSLDNPDLGPFLLKLARDAIASGEGPNKALDYAIRATKSFERCCAAVAPPIPGGSDGGPVLDLAMSLHVLAAIYCSLGRFDEAVPPLERAIQVPDPTRGPDHSLAAFSGHMQLGDTLSMLGQIDRSIACYEEGLKIQIQTLGDTDPRVGETCRYLAEAYVQAMQFNKAEELCKKTLEIHRAHSEPASLEEAADRRLMAIICEAKGDYENALEHLVLASMAMIASGQESEVASIDVSIGNIYMSLCRFDEAVFSYQKALTVFKASKGETHPTVASVFVRLAELYHRTGKLRESKSYCENALRIYNKPVPGTTVEEIAGGLTEISAIYESVDEPEEALKLLQKSMKLLEDKPGQQSAIAGLEARMGVMYYTVGRYEDARNAFESAVTKLRAAGEKSAFFGVVLNQMGLACVQLFKIDEAGELFEEARGILEQERGPCDQDTLGVYSNLAATYDAMGRIEDAIEILEQVLKLREEKLGTANPDFEDEKKRLAELLKEAGRSRNYKAKSLQNLIDPNARPPKKESSAKKWPSLGFKF
What are the official names of this protein?
Protein KINESIN LIGHT CHAIN-RELATED 1.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Note=Recruited by IQD1 to microtubules.
Protein: KDGD_CORGB
Sequence: MARFSPQDLADHLKDGLLSFPATAFQDDLEVDEVAYVEHIEWQSSYPVAGLFAAGGTGEGFSLTVEENHRVTQLAVQASSPEVPVLGSATGSTKSAIANAQGAEAAGAEGVLLLPPYLTECDAEGLYNHAAAVCESTSLGVIVYNRANAIYSPEVIARLSERYPNFIGFKDGTGNIEHLAKITTLCGDRLFYLGGLPTAETFALPLLQMGMSTYSSAMFNFIPDFALSFYADVRAQDSAAVKQKLSDFVLPYLDIRDRAQGYGVSIVKGGLKAVGRNAGGVRPPLRNLSEQDIADLSDLLATSGAGSYRLPVEVKA
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: COBS_SHEB5
Sequence: MSERESWHKEIDLFLVAMGYFTRIPMPKWVEADSDKLNKASRYFGLVGLLVGLLSAIVFWLTQNWLPAGVSVLLAMLVGVLLTGGFHEDGLADTFDGFGGGWTAEDKLRIMKDSRLGSYGALALMLALLLKWQLLVELALYDPVVAGSALIVAHTVSRMVSASIIFSEKYVRDDETSKSKPLSQHQGINELLILIASGVLVLLFLKGLAALSLLLVMIGLRRLIIVIFRRQIGGYTGDTLGAAQQIAEIVCYFVLLVVGNIL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUD_METRJ
Sequence: MEKFTTLEGVAAPLRTINVDTDRIIPAKYLKTIRRTGLGKSLFAEMRYREDGSENPDFILNQPAYRNSKILVCGDNFGCGSSREHAPWALADFGIRCVISTSFADIFFNNCAKNGILAIVVSPEDLEKLFEDAERGANATLTVDLAAQTIRGPDGGTLHFDVDEGRKHNLLNGLDEIGLTLERVSSIDAYEQKLAQRTWA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: SWI5_ANOFI
Sequence: MNTEQSAEPHYSNSKCLISTPEGKDLKNGAVKRTPSSKFKRVHSNFKSPLQVPESAKVSPAEEVAELEGRREQLDAEIAQLEVEGCRVEELEHHIDMLHEYNDIKDIGQSLLGRIAAVRGTTTRDLYSHFGLELDD
What is the function of this protein?
Component of the swi5-sfr1 complex, a complex required for double-strand break repair via homologous recombination.
What are the official names of this protein?
DNA repair protein SWI5 homolog, Protein SAE3 homolog.
What is the protein family that this protein belongs to?
Belongs to the SWI5/SAE3 family.
What are the subcellular locations of this protein?
Nucleus.