PharMolix/UniProtQA huggingface dataset:
Protein: ARGX_SULAC
Sequence: MRVALVVDIVRQEEKLIAKALEKFQLQYDVINVAQEPLPFNKALGRYDVAIIRPISMYRALYASAVLESAGVHTINSSDTISLCGDKILTYSKLYREGIPIPDSIIAMSSDAALKAYEQKGFPLIDKPPIGSWGRLVSLIRDIFEGKTIIEHRELMGNSALKVHIVQEYINYKSRDIRCIVIGSELLGCYARNIPSNEWRANIALGGYPSQIEVDHKLKETVLKATSIIGGEFVSIDVMEHQSKNYVINEFNDVPEFKGFMLATNIDVAEELVSYVKNNYLR
What is the function of this protein?
Catalyzes the ATP-dependent formation of a covalent bond between the amino group of glutamate and the gamma-carboxyl group of the C-terminal glutamate residue in LysW.
What are the official names of this protein?
Glutamate--LysW ligase ArgX.
What is the protein family that this protein belongs to?
Belongs to the RimK family. LysX subfamily.
Protein: SYC_STAAR
Sequence: MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQELNQTVPEIAEKYIAAFHEDVGALNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSIDDLKVGARIDAGEHKEDALDFTLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGATIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILVHDIIKEVDPDVLRFFVISVHYRSPINYNLELVESARSGLERIRNSYQLIEERAQIATNIENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDKFKAVYQIFSDVLGVPLKSKKADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQNIILEDTPQGVRFKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM71_MOUSE
Sequence: MYRDSPLMSTPVANDSRSDEGPSGKLSPTCLFPSFTCDFLDGDSSFECCSIDPLTGSHYICRRSPRLLTNGYYIWTEDSFFCDPDGHITLNPSQTSVMYKENLVRIFRKKKRTHRSLSSLLDPRASKSWLHGSIFGEVDSLPSEDLWLDGIRSLGSDLDCSLSDGWESQKPVTDTSESSSSGYILPQSLRESSQSSSLQLQVKASGHFEKNSLVHSRAGLMHKVSFQAILLAVCLVISAYTRWFVGGELASIFTCALLITIAYVVKSLFLNLARYFKATSCARFDST
What are the official names of this protein?
Transmembrane protein 71.
What is the protein family that this protein belongs to?
Belongs to the TMEM71 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ENO2_HEVBR
Sequence: MAITIVSVRARQIFDSRGNPTVEADVKLSDGYLARAAVPRGASTGIYEALELRDGGSDYLGKGVSKAVENVNIIIGPALVGKDPTDQVGIDNFMVQQLDGTVNEWGWCKQKLGANAILAVSLAVCKAGAHVKGIPLYKHVANLAGNKNLVLPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFKEAMKMGAEVYHHLKSVIKKKYGQDATNVGDEGGFAPNIQENKEGLELLKTAIAKAGYTGKVVIGMDVAASEFYGSDKTYDLNFKEENNNGSQKISGDVLKDLYKSFVTEYPIVSIEDPFDQDDWEHYAKLTSEIGVKVQIVGDDLLVTNPKRVEKAIKEKACNALLLKVNQIGSVTESIEAVKMSKRAGWGVMASHRSGETEDTFIADLSVGLATGQIKTGAPCRSERLAKYNQLLRIEEELGAEAVYAGANFRTPVEPY
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_SALSV
Sequence: MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: NUSB_TERTT
Sequence: MKVTAATRSRARHFAMQAIYQWQMNGNPLHVIEAEFHTDNDMSKVDTEYFHELFHGVAADKSALDACFLPHLKSLPLEKLDPVTLALLRQATFELKNRVDVPYKVVINEAVNLAKKFGAEDSHKFVNGVLDKVAADLRALEFNAARS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: UREE_EDWIC
Sequence: MIVISHVLGNVKTDPVWAEKLKAYELDYLTLEHGDMYKNSCRKMTEQGKDLGISLERNSLLADGDVLLCDDKHAYAIIVKLILRDVMIIDLTDLLNFSHEMMLKISFELGHALGNQHWKSIIHESQVFVPLSVSHKVMESVIQTHRFTGIHYRFEKGDSILSCLTPSEARLLFGGAEDLGAHVHVDHSHSHDFMGHSHEHEGHRHVHNHAGNSHDNEHDEHHSRR
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_HELPJ
Sequence: MVALSNALSRVFGSVAGYKFPSFIQKSINALYVKIFKIDLSEFEPLENYKSLNALFMRSLKKERPFDKAPNICIAPCDALITECAFLDNDSALQIKGMPYKAHELVGEINPLSPSFFYVNFYLSPKDYHHYHAPCDLEILEARYFAGKLLPVNKPSLHKNKNLFVGNERVALVAKDIQGNKLYFVAVGALNVGKMRFNFDKNIQTNAKARFMQTYSYNPPIKVKKGDNLGNFEMGSTIVLFIQNTAFKDLKEKSVKFGESIGEFHAN
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PA2A_CROAT
Sequence: MRTLWIVAVLLLGVEGSLVQFETLIMKIAGRSGLLWYSAYGCYCGWGGHGLPQDATDRCCFVHDCCYGKATDCNPKTVSYTYSEENGEIICGGDDPCGTQICECDKAAAICFRDNIPSYDNKYWLFPPKNCREEPEPC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNPH_FRATM
Sequence: MRPSGRNNDQLRNLKVTHNFTKHAEGSVLIEFGDTKVICTASVVAGVPKFKKDSGEGWLTAEYGMLPRSTHMRMDREAARGKQSGRTQEIQRLIGRALRASVDLTAIGENTIKIDCDVIQADGGTRTASITGASLAIADAIEYMKQNGMLDEQANPLLSQVAAISVGIYNNEPVLDLDYDEDSNAETDMNVVMNSNGGIIEIQGTAEGKDFSEEEFAKMLGLAKKGIKEIFATVF
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: PGK_PSEFS
Sequence: MTVLKMTDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVAEYLSKALGRDVPLVADYLGGVDVKAGDIVLFENVRFNKGEKKNSDELAQQYAALCDVFVMDAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGAPAQPMAAIVAGSKVSTKLDVLNSLSQICNQLIVGGGIANTFLAAAGHPVGKSLYEPDLLDTARAIAAKVSVPLPVDVVVAKEFAESAEATVKLIADVADDDMILDIGPQTAANFAELLKASQTILWNGPVGVFEFDQFGNGTKVLAKAIAESSAFSIAGGGDTLAAIDKYGVADQISYISTGGGAFLEFVEGKVLPAVEVLETRAKG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABEC2_PONPY
Sequence: MAQKEEAAAATEAASQNGEDLENLDDPEKLKELIELPPFEIVTGERLPANFFKFQFRNVEYSSGRNKTFLCYVVEAQGKGGQVQASRGYLEDEHAAAHAEEAFFNTILPAFDPALRYNVTWYVSSSPCAACADRIIKTLSKTKNLRLLILVGRLFMWEELEIQDALKKLKEAGCKLRIMKPQDFEYVWQNFVEQEEGESKAFQPWEDIQENFLYYEEKLADILK
What is the function of this protein?
Probable C to U editing enzyme whose physiological substrate is not yet known.  Does not display detectable apoB mRNA editing.  Has a low intrinsic cytidine deaminase activity.  May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
What are the official names of this protein?
Probable C->U-editing enzyme APOBEC-2, mRNA(cytosine(6666)) deaminase 2.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: H13K1_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEKALSEEFTELIHEKEAASETEARECRYFWGECHDHMPCCDWLVCGYKWPITYNICVWNRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1i, U7-TRTX-Hhn1i, Hainantoxin-XIII-11, HNTX-XIII-11.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLGA_STRR6
Sequence: MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYYDMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDFDDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVLTIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSYAHEIMTSQFGCNLDHILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAKNKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPAFEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGTLPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNLQKQAMESDFSWDTACKSYLDLYHSLVN
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: YVDI_VACCC
Sequence: MNFSYSRRWLVYLTYYSPRFLYKRWFNLYILNHISNKAQFRNINKFFVERFKVERRVTNNDIGYWIEGYRYGNF
What are the official names of this protein?
Uncharacterized 9.5 kDa protein.
Protein: GMH1_SCHPO
Sequence: MLSFFTKNTLTKRKLIMLALAIVFTFFAFGLYFIPHDEISVFDFKLPALQYETTVTSLDNFLIGGSTTLYTATVNHEDLNEPKSHEIVMLLASDGNVGSFESNLLDDCFKNRIEYAKLQNYNFEFVNVSSLVVPPVWGKMPAILQTMRKYPSAKWIWWLDQDALIMNKNLSLQELFLSPAMLQKSLLREQPIINSFGEDNFRITPAAYSKEMIEQIQFLISQDHNGLNAGSFLVRNSRSIALLMDLLTDPSLADAGVVRHEQDLIGYFIQKHSQVASMVGILPQRFINAFHEGPPTMQWQEGDLALHFAGCWVENKCAELWTKYKDKII
What are the official names of this protein?
Probable alpha-1,2-galactosyltransferase gmh1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: YACL_SHIB3
Sequence: MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQAAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCGVEDFLQVVAAYRNFVQQK
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: SECA_STRTD
Sequence: MANILRKIIENDKGEIKKLEKTAKKVESYADAMAALSDEELQAKTEEFKQRYQNGESLDQLLPEAFAVVREGAKRVLGLFPYRVQIMGGIVLHYGDVAEMRTGEGKTLTATMPVYLNAISGEGVHVITVNEYLSERDATEMGELYSWLGLSVGINLSSKSPAEKREAYNCDITYSTSSEVGFDYLRDNMVVRKENMVQRPLNFALVDEVDSVLIDEARTPLIVSGPVSSETNQLYHRADAFVKTLTEDDYAIDIPTKTIGLNDSGIDKAEEFFNLENLYDIDNVALTHYIDNALRANYIMLRDIDYVVSPEQEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVPVQEETKTSASITYQNMFRMYKKLSGMTGTGKTEEDEFREIYNMRVIPIPTNRPIQRIDHDDLLYSTLDAKFRAVVQDVKRRYEKGQPVLIGTVAVETSDLISKMLVDAGIPHEVLNAKNHEKEAHIIMNAGQRGAVTIATNMAGRGTDIKLGEGVLELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGSDRIKHVLERLNADDEDIVIKSRMLTRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAERYDVITAERDLEPEIKAMIKRTINRTVDGHSRNDQEEALKGILNFARQALVPEDAISLEDLKEVGEVTKRSVNYDAIKVYLTELADNVYDRQIKKLRSEEAIREFQKVLILMVVDNKWTDHIDALDQLRNAVGMRGYAQNNPIVEYQSESFKMFQDMIGAIEYDVTRTMMKAQIHEQSREHVNERVSTTATGNIQAHQADANGQEIDFSKVGRNDFCPCGSGKKFKNCHGRKQF
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: CHH_ASTAS
Sequence: QVFDQACKGIYDRAIFKKLDRVCDDCYNLYRKPYVATTCRQNCYANSVFRQCLDDLLLIDVVDEYISGVQIV
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction.
What are the official names of this protein?
Crustacean hyperglycemic hormone, CHH.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Protein: ADD_ECO5E
Sequence: MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLNAEEKRALREKVAAK
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: ATPG_NOCSJ
Sequence: MAVSLREYRARIKSTESMKKITRAMELIAASRIIKAQQRAQSAAPYARELTRAVSAVATYSNVDHPLTREPENSQRVAMLIVTSDRGLAGAYSSSVLKEAERLAEKLRGEGKTIDVYLCGRKGEAYHRFRNRPVVRSWTGFSDQPSYDAALEVGTTLIDAFLDEEGEHAVDEVHVVYTRFRSMLLQEPTAVRLLPLEVVEGEERPASDEVLPLYEFEPSAEAVLDNLLPQYVQSRIFFAFLQAAASELAARQKAMKSATDNADELIKKYTRIANQARQAGITQEISEIVGGVNALADAQAGSE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1699_STRP8
Sequence: MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVRHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS
What are the official names of this protein?
UPF0291 protein spyM18_1699.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I11RA_MOUSE
Sequence: MSSSCSGLTRVLVAVATALVSSSSPCPQAWGPPGVQYGQPGRPVMLCCPGVSAGTPVSWFRDGDSRLLQGPDSGLGHRLVLAQVDSPDEGTYVCQTLDGVSGGMVTLKLGFPPARPEVSCQAVDYENFSCTWSPGQVSGLPTRYLTSYRKKTLPGAESQRESPSTGPWPCPQDPLEASRCVVHGAEFWSEYRINVTEVNPLGASTCLLDVRLQSILRPDPPQGLRVESVPGYPRRLHASWTYPASWRRQPHFLLKFRLQYRPAQHPAWSTVEPIGLEEVITDAVAGLPHAVRVSARDFLDAGTWSAWSPEAWGTPSTGPLQDEIPDWSQGHGQQLEAVVAQEDSPAPARPSLQPDPRPLDHRDPLEQVAVLASLGIFSCLGLAVGALALGLWLRLRRSGKDGPQKPGLLAPMIPVEKLPGIPNLQRTPENFS
What is the function of this protein?
Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity.  The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
What are the official names of this protein?
Interleukin-11 receptor subunit alpha-1, IL-11 receptor subunit alpha-1, IL-11R subunit alpha-1, IL-11R-alpha-1, IL-11RA1, Enhancer trap locus homolog 2, Etl-2, Novel cytokine receptor 1, NR-1, NR1.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 3 subfamily.
What are the subcellular locations of this protein?
[Interleukin-11 receptor subunit alpha-1]: Membrane; Single-pass type I membrane protein. Secreted. SUBCELLULAR LOCATION: [Soluble interleukin-11 receptor subunit alpha]: Secreted.
Protein: HCHA_SHIF8
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHSDNPLNGYSICAFPDAADKQTPDIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKRLTGDSPFAANALGKLAAQEMLAAYAS
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_METPP
Sequence: MLLIPAIDLKDGRCVRLKQGDMNVSTTFGEDPVAMARRWLDAGARRLHLVDLNGAFAGKPVNEPAIKAILKEVGDEIPVQLGGGIRDLDTIERYLDDGLSYVIIGTAAVKNPGFLRDACTAFGGHIIVGLDAKDGKVATDGWSKLTGHEVVDLAKKFEDYGVEGVIYTDIGRDGMLSGINIDATVKLAQALTIPVIASGGLSDIADIERLCAVEGEGIEGVICGRAIYTGDLDFAAAQARADALNGDA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_BACC7
Sequence: MATEKTYPMTQEGKQKLENELEDLKTVKRKEVVERIKIARSFGDLSENSEYDAAKDEQAFVEGRITQLENMIRNAVIITDNGEESTVVTLGKTVTFKELPDGDEEAYTIVGSAEADPFEGRISNDSPIAKSLLGKQIGEKVAIQTPGGEMQVEIISVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: LN28B_XENLA
Sequence: MAEGGAARGTREEQGKLPEQEEEEEEDPQVLLGSGHCKWFNVRMGFGFISMTSREGSPLENPVDVFVHQSKLYMDGFRSLKEGEPVEFTFKKSSKGFESLRVTGPGGNPCLGSERRPKAKTVQKRKPKGDRCYNCGGLDHHAKECNLPPQPKKCHYCQSTMHMVANCPHKIVPQHPTTSQGRYEAEPQPSTSSFQREGGGAFDYSSPSYSQEGRSELSERSSRSPQEASLSKISTSPEEQSRKGPSVQKKKK
What is the function of this protein?
Suppressor of specific microRNA (miRNA) biogenesis.  Binds target primary miRNA transcripts and sequester them in the nucleolus, away from the microprocessor complex, hence preventing their processing into mature miRNA.  The specific interaction with target pri-miRNAs occurs via an 5'-GGAG-3' motif in the pre-miRNA terminal loop.
What are the official names of this protein?
Protein lin-28 homolog B, Lin-28B.
What is the protein family that this protein belongs to?
Belongs to the lin-28 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NUOG_BUCAP
Sequence: MAKIYVDGKAYCMSESDNLLQACLSSGLNIPYFCWHPILGSLGACRQCAVTQYNSSLDNQGKLIMSCMTPVIDGTIISINDDTSKKFRSNIVELLLTNHPHDCPVCEEGGNCHLQDMTVMTTHNFRNYRFSKRTHKNQYLGSFIKHEMNRCIGCYRCVRYYRDYADGTDLDVYGANNNIYFGRIEHGVLENEHSGNLIEICPTGVFTDKTHSKKYNRKWDMQYAPGICQNCSIGCNISIGERYGEIRRIENRYHESINHYLICDLGRFGYSHTNLKNRPKKPILSTKENDVNILNFNKAIEYATNFFQRYKNVIGVGSIRSSIENNFALQELVGKENFCNGMSDKENSCIKLILDTLKNNQLYIPSLKEIESYDTILILGEDLTQTAPRIALAVRQAMKNKAKDLAELYGIPKWNAAPISQISEIYKNYLYIFNTHETKLDNIADWSYFSSIDNQVRFARAIAYELDKNLPDISFLDSNLRKKASLIAKKIISSKKVLIISGSHVYSKSIIQASINIAISINQKNINHVGLTFVTSSSNTLGLGILGGFSIENALKKLKNREAEAIIFMEYDLYRYISKHDCDVLFKKNDNIMSIDHQYTQTYKNSGFALPSVNFTESSGTIVNFEGRAQRFFQVYDPMFYDKKNCLYVSWKWLSFIKSKIEKKEISWINLDNIISEYSDKYPIFKKIKTAGPNASFRVHGQKIARSPHRSSGRTALRANINIHEPSQPKDADTMFSFSMEGYSQPNKSISHIPFAWFPGWNSPQAWNKFQKEIGRQLISGDSGVHLFKSNKKILDIYFHFSPKKFIKEKYWYVIPYYHIFGNEELTQYSSIIKQNIPLEYVLISELDGLELGLKKNSIVEFNCLNQDFRLPIRLSKHLTSKHIGLPIGRKGFPISLIGEKVKSLWEVMS
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
Protein: SECB_ACIBY
Sequence: MSEEQQVQPQLALERIYTKDISFEVPGAQVFTKQWQPELNINLSSAAEKIDPTHFEVSLKVVVQANNDNETAFIVDVTQSGIFLIDNIEEDRLPYILGAYCPNILFPFLREAVNDLVTKGSFPQLLLTPINFDAEFEANMQRAQAAAVEGQA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1195_STAES
Sequence: MDLNFDLYMNDVVEQARNEIEHAGYQQLTSAEDVDQVLQQKGTSLVMVNSVCGCAGGIARPAAAHALHYDKLPQRLVTVFAGQDKEATQQAREYFEGYAPSSPSFALIKDGKITEMIERHQIEGHDVMDVINQLQALFDKYCEER
What are the official names of this protein?
UPF0403 protein SE_1195.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: IRAP_SALPK
Sequence: MKNLIAELLLKLAQKEEESKELVAQVEALEIIVTAMLRNMAQNEQEMLIRQVEGALEGVKPDASVPDHDTELLRQYVKKLLRHPRH
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate and magnesium starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.