PharMolix/UniProtQA huggingface dataset:
Protein: POLG_SVSAP
Sequence: MVSKPFKPIVLNATFEWQVFKRCYLRVAPREAFCENLSELHHYFARRVNAWLKHATRTLPDGYTFVEEGLLDMFGTKAPDSVQEGTLFRELFGVDQTEQFPLSLADLAKLQGELVDATRTPGHALRQKYTMTTIQDLINKITKVVPVQATLTEMHARRQFERERADLFHELPLVDEDAVSQPKTYFYTMWRQVVKKGKAYFCPLVKTSAWRTKISAITEPIKDFLIAFCQAVQQEMGVNPQYLQLAWLQKLKPTTLTIILQQHKYTVSGWLATMTALVEVYSNLFDDLRKSSVAIVSSIGAFFDICKDFVSQVVELVKTTFTAQGPTDLGWAAVLAGAAMILLKMSGCPGVIGMWTKVLKICGGITTITAAARGVRWLKDLYEEAEGRRLAKMYMARGAALIELAASREVTGIDELKGLLDCFTILIEEGTELIHKFGTSPLAGLVRTYVSELETQANNIRSTIKLDTPRRVPVVIILTGAPGIGKTRLAQYVGQRFGKTSNFSVAVDHHDGYTGNTVCIWDEFDVDSKGAFVETMIGIANTAPFPLNCDRVENKGRVFTSDYVICTSNYPTSVIPDNPRAAAFYRRVLTVDVSAPDLEEWKKRNPGKRPTPDLYQDDFSHLKLMLRPYLGYNPDGDTLEGPRVAPTQISIAGLITLMERRFKEQAGPLQNLWLQVPKTLVEQSTNMVKAFMYANRAVCDVIPNPATRDIAETALTKIFVCGTAPPPEFVGKHIVITGIEVGDASIANSLLSMFTTTTRLSAAAQREYMYRVWSPLIHIQDRSINTQNLPYINRVIPVTSHWDFLRGLRHHLGFTSIPGMWKAFQGWRTSQGIVDFVAHHMADVTFPSNPECTIFRTPDADVVFYTFGSYVCFATPARVPYVGTPPTTIHSNTPRCMTWGETIALLCEVVAEFVLHFGPVILSAANIAYLMTRGSRTEEAKGKTKHGRGMRHGHRAGVSLSDDEYDEWRDLMRDWRRDMSVNDFLMLRERSALGVDDEDEARYRAWLEIRAMRMAGGAYTHATIIGRGGVRDEIIRTAPRRAPTRPQQHYEEEAPTAIVEFTQGGDHIGYGVHIGNGNVITVTHVASTSDEVNGSAFKITRTVGETTWVQGPFSQLPHMQIGSGSPVYFTTRLHPVFTISEGTFETPNITVNGFHVRIMNGYPTKKGDCGLPYFNSNRQLVALHAGTDTQGETKVAQRVVKEVTTQDEFQWKGLPVVKSGLDVGGMPTGTRYHRSPAWPEEQPGETHAPAPFGAGDKRYTFSQTEMLVNGLKPYTEPTAGVPPQLLSRAVTHVRSYIETIIGTHRSPVLTYHQACELLERTTSCGPFVQGLKGDYWDEEQQQYTGVLANHLEQAWDKANKGIAPRNAYKLALKDELRPIEKNKAGKRRLLWGCDAATTLIATAAFKAVATRLQVVTPMTPVAVGINMDSVQMQVMNDSLKGGVLYCLDYSKWDSTQNPAVTAASLAILERFAEPHPIVSCAIEALSSPAEGYVNDIKFVTRGGLPSGMPFTSVVNSINHMIYVAAAILQAYESHNVPYTGNVFQVETVHTYGDDCMYSVCPATASIFHAVLANLTSYGLKPTAADKSDAIKPTNTPVFLKRTFTQTPHGVRALLDITSITRQFYWLKANRTSDPSSPPAFDRQARSAQLENALAYASQHGPVVFDTVRQIAIKTAQGEGLVLVNTNYDQALATYNAWFIGGTVPDPVGHTEGTHKIVFEMEGNGSNPEPKQSNNPMVVDPPGTTGPTTSHVVVANPEQPNGAAQRLELAVATGAIQSNVPEAIRNCFAVFRTFAWNDRMPTGTFLGSISLHPNINPYTAHLSGMWAGWGGSFEVRLSISGSGVFAGRIIASVIPPGVDPSSIRDPGVLPHAFVDARITEPVSFMIPDVRAVDYHRMDGAEPTCSLGFWVYQPLLNPFSTTAVSTCWVSVETKPGGDFDFCLLRPPGQQMENGVSPEGLLPRRLGYSRGNRVGGLVVGMVLVAEHKQVNRHFNSNSVTFGWSTAPVNPMAAEIVTNQAHSTSRHAWLSIGAQNKGPLFPGIPNHFPDSCASTIVGAMDTSLGGRPSTGVCGPAISFQNNGDVYENDTPSVMFATYDPLTSGTGVALTNSINPASLALVRISNNDFDTSGFANDKNVVVQMSWEMYTGTNQIRGQVTPMSGTNYTFTSTGANTLVLWQERMLSYDGHQAILYSSQLERTAEYFQNDIVNIPENSMAVFNVETNSASFQIGIRPDGYMVTGGSIGINVPLEPETRFQYVGILPLSAALSGPSGNMGRARRVFQ
What is the function of this protein?
Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins.  The capsid encapsulate the genomic RNA and VP2 proteins.  Attaches virion to target cells, inducing endocytosis of the viral particle.  Acidification of the endosome induces conformational change of capsid protein thereby injecting virus genomic RNA into host cytoplasm (By similarity).
What are the official names of this protein?
Genome polyprotein.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm.
Protein: RS18_CAMJJ
Sequence: MAEKRKYSRKYCKYTEAKVEFIDYKDTAMLKHALSERFKIMPRRLTGTSKKYQEMVEVAIKRARHVALIPYIVDRKEVINNPFEGL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: THIC_CORJK
Sequence: MTDTSTQNTATPTDEYGAEIHPKHSFSPIEKTVESFGKTFTLEVPETEIQLDDSPTGPNEPVRIYRTRGPWAEPTKGLEGLRSEWIEARDDVEAYEGRRRNLLDDGNRAVKRGEASEEWKGSTRPTLRAKEGKRVTQMHYARQGIITPEMEYVALREHCDVEKVREQVASGKAIIPNNINHPESEPMIIGNAFTTKINANIGNSAVTSSIREEVDKLRWATRWGADTVMDLSTGNDIHTTREWILRNSPVPIGTVPIYQALEKVDGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVRLPFVPLTTKRVTGIVSRGGSIMAGWCLAHHKESFLYENFDELCEIFAKYDVAFSLGDGLRPGSIADANDAAQFAELKTIGELTHRAWEYDVQVMVEGPGHVPLNMVQVNNEKEQEWCGGAPFYTLGPLVTDIAPGYDHITSAIGAANIAMGGTAMLCYVTPKEHLGLPNKDDVKTGVITYKVSAHAADVAKGHPGAHEWDDAMSKARFEFRWHDQFALSLDPDTAQAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDAFGDEIDEALATDQKQSLVKDLGLPGFGRQSVDGIDSLSAAGEEEMAEEFRRAGSQLYLNRDEAKEVAEDLQKEAAAHGER
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: FMT_CHLT2
Sequence: MSLRVVYLGTPQFAATVLKTLLDAHTHIVGVVTRADKPQKRSSKLISSPVKQLALSKNIPLLQPIKTTDPAFLAQLREWQADVFIVVAYGVILKQELLDIPTYGCYNLHAGLLPAYRGAAPIQRCIMDGGVLSGNTVIRMDAGMDTGDIANVNYVAIGEDMTAGGLAEALAASGGELLLKTLQEIEAGTVRHVPQNEAMATLAPKLTKEEGGIHWDAPASQVYAHIRGVSPAPGAWTRYLSQGKEARRLGVLSARMESFSGNYGDPGEVLGVSGEDLLIACRQGALRLRMVQPEGKASMKAKDFFNGQSRLVSKLF
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SPC1D_EMENI
Sequence: MAKPHCSSRSGLLALPRGGSGQPGYGTQSSSNVVGDIDVRASTHKLNRKDNSADKGDTLRPEFSGDPDSEVENNKFAFSPGQLDKLLNPKNFGAFGAFGGLRGLENGLRTNVQSGLSMDETVLDGMVNFNEAVSRTFVPAPKSASPAPLAP
What are the official names of this protein?
Conidium-specific protein.
Protein: KEFB_SALPA
Sequence: MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRGLIPEHSDMVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RK27_CALSH
Sequence: STKNGRDSNSKRLGVKVYGNQPVKAGGIMIRQRGLTFKPGISVSVGKDYTLFATQNGYVQFETINDKKFVSVVG
What are the official names of this protein?
50S ribosomal protein L27, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MATK_TRITL
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFMENGGYDNKYSLLNVKRLITRMYQQNHLIISANDSNKNPFLGYNKNFYSQIISEGFAIIVEIPFFLQLSSSLEEAEIIKSYKNVRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILIQILRYWVKDVPFFHLLRLFLYHFCNWNCFIPTKKSISTFSKRNPRLFLFLHNFYVCEYESIFLFLRNKSSHLRLKSFSVFFERIFFYAKREHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKYYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFSLHRFHRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: OTC_PHOPR
Sequence: MSFNLRNRNFLKLLDFTGKEIEHLIALAQDLKHAKYAGTEQQKLKGKNIALIFEKTSTRTRCAFEVAAHDQGAHVTYIGGGSQMGHKESTKDTARVLGRFYDGIEYRGFGQDVVETLGEHAGVPVWNGLTDEWHPTQIIADWMTMLEHGNGKRLNQMKLAYMGDAKNNMGNSLMVGAAKVGMEIRLVGPKAYWPDPALVAECNELCKISGGKIVITDNVQEGVDSVDFIYGDVWVSMGEPEELWATRINDLAPYQVNMSVITATQNPAVKYMHCLPAFHNDETRVGKKIEEKFNMKGLEVTEDVFESSYTICFDEAENRMHSIKAIMVATLGD
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT8_EVATR
Sequence: SGSCSIQTCWDQLGAFDIIGEALRKRYETAVLVDYINGNLFPSEVKSKDASEPVDKSDLAFLELSPNYCQLNSTIGAVGTLGRECLRGRGVDEVSEWEARSCKRLCTSCGLGVKRTKVVVSSSCNCKF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-8.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: MNMC_MAGMM
Sequence: MSKQQAPNTTGIGTADLQWHSDETPYSPRFDDIYYAPTHGAEESTHVFLEGINAPACWQQRPHYTLAETGFGTGLNFLLTLDLWLATAPAHGRLHYIAVEAYPMDQAALARAHAPFAWLAPHSAALVQAWPPAVAGFHQRSLAQGRVTLTLLFGPAASMLAQLSATVDGWYLDGFAPSRNPEMWSDTLFAQLSRLSRLGTRLASFTVAGTVKRGLRAQGFTLHKAPGFGQKRECLRGVLENPLPHKPNIPPWYAPPQRSEPVSSVAIIGAGIAGAACAYACRRAGLQVTLFERHAQPGAEASGNPSGLFSPRLTAGVSLDGRFHAAAYFHALDLYAQLAQHTPEIYHPGRGLLQMAESEADVQRLQQALFHSAWPPQHAQWWDAATASQQLGTPLPRGGLWHAQAGALNPSVLCAALLADVTAHYQTEIVRLAPQPEGWTLHTAQRHYGTFDAVVIAAGATAPLLYPEAEIPNTAVQGQLSILPAANPLNQHALVFGGYLTPPYQDEQGQLCQVLGSTYRPWDDLSDCSWSECQPEAHQLVWQQLNETLPQLGQQWLGPARQGRAALRAAMKDHFPLFGPLINPSAYRTNYATLYQGKRVSLAKPAVYIDGLYLIGGLGSRGLLTAPLFGACMAALLSGGPLPLEADLWCAVHPARLLVRSLKKPPL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1279_LACAC
Sequence: MNKDAMSKEEKKVTDRINELYHKKENEGLTPEEEEERKELHKKFLANFRAAFKQDVENMVILDKNGKEVTSEKAKQAQRKKGLRKD
What are the official names of this protein?
UPF0291 protein LBA1279.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_LISIN
Sequence: MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTR86_CANGA
Sequence: MSEKKKILQDIDRLLSEANSDPQLYHDNLGLLNDFVIETANNTAIRDKFSRDKETWQLIKTILVNSHVEDISGWSAEVIFLYKRLLRGVFILARNLAVSGSEIAQELLLQNIAYKIFNNSLKVGKLDDGMQLALYSTILSFLHNMSSKSVVFDRSSSKELFEFLHFPVKLNYEYTKDILLPYLLYFKDLIQHDDFLYYFLRYDKVDSILCGLILDKIMRDESQIFEIVSGTRIVSPDVNLSDIDMILLRTFALISTHESFIPYLEDKENNSFNIFIDLLKLMQLVVTNIDSWDKFQLTSIMTWTYKIFEKNADQIKNYFKNKLENEEIAKKLHAKCVITLDIMAKLCQFNHVQKFIISYKGLDQLISLLNIFQDNLIRVNFTKTSQASDITGVKATNKLGEKLAKDSLIEERIDLINMKIKETNFPECKLLIIEIIAMLTHENREIQNQVRELGGLGVILSNCVIDDNDPFIKERSIMCIKFLLKDNKENQNFVANLESKRVANDETLQEAGYEVDISKDGKLSLKSTNQ
What is the function of this protein?
Essential protein which may be involved in threonine biosynthesis.
What are the official names of this protein?
Copper transport protein 86.
What is the protein family that this protein belongs to?
Belongs to the CTR86 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARFB_XENLA
Sequence: MASEDEVSEFLGQNPETAAWLERVRGQCESDKLWRYRREFILRNLSDVCGEGEIPPPPETNHKELDRLLAYSMVWANHVFTGCRYPIQVIEKVLKMAENIKVTDAPTHTTRDELVAKVKKRGNSSSNEGVEELPRKKKKSNDHGARESSYIDDTVEIRNQPGDARERSSGKICDGYIPSTSLNKREAHSRTDVNTEFYEESGNGRPLPVSKAKSSLNPPEEAGYKHAATQGRKSHSDSRYQTAVKGPSQSSDNALKPTRRFTTEHTKERQPFFNRLYKTVAWKLVSAGGFNANLNHEELLNTSIESLKATLEIAFVPLKDLADFPQNKTSQENTVCELRCKSVYLGMGCGKTMDTAKAVAFREAVKLFLKKKVVVRICRRKFNGRDVEDLVLVDEEFRPPNLPPAVKNPHELV
What is the function of this protein?
May regulate DNA damage response and cell proliferation.
What are the official names of this protein?
Protein CDKN2AIP homolog B.
What is the protein family that this protein belongs to?
Belongs to the CARF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: STH_PANTR
Sequence: MSEGGGRVSRIFAAPTRLCRWPALIECGVNLTQPLCEWMIQVARDRTLSLAWEVASLLTLSSSEVGLEGVGTIWPSSYSSEENSRNGAEQGRQLSIEGPFQGQNCPSHPAAALPLPMRGESQATSCQV
What are the official names of this protein?
Saitohin.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YC73_SCHPO
Sequence: MLPHTAFSNHIHYHFINEAPFRLCIYTLFHAHTCFSCGLSLSLMEV
What are the official names of this protein?
Uncharacterized protein SPCC417.03.
Protein: RL1_YERPB
Sequence: MAKLTKRMRVIRDKVDVTKQYDINEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFAQGANAEAAKEAGAELVGMDDLADQIKKGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDSDKLKENLESLVVALKKAKPATAKGIYIKKISLSTTMGAGVAIDQSGLTAVVN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: WNT2_SHEEP
Sequence: MNACLVGIWLWLPLLFTWLSPEVSSSWWYMRATSGSSRVMCDNVPGLVSHQRQLCHRHPDVMRAIGLGVTEWTMECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDNKGTFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGNYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHITRKTKCECKFHWCCAVRCQDCVEALDVHTCKAPKSPDWAAPT
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity).  Functions as upstream regulator of FGF10 expression.  Plays an important role in embryonic lung development.  May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: NU107_HUMAN
Sequence: MDRSGFGEISSPVIREAEVTRTARKQSAQKRVLLQASQDENFGNTTPRNQVIPRTPSSFRQPFTPTSRSLLRQPDISCILGTGGKSPRLTQSSGFFGNLSMVTNLDDSNWAAAFSSQRSGLFTNTEPHSITEDVTISAVMLREDDPGEAASMSMFSDFLQSFLKHSSSTVFDLVEEYENICGSQVNILSKIVSRATPGLQKFSKTASMLWLLQQEMVTWRLLASLYRDRIQSALEEESVFAVTAVNASEKTVVEALFQRDSLVRQSQLVVDWLESIAKDEIGEFSDNIEFYAKSVYWENTLHTLKQRQLTSYVGSVRPLVTELDPDAPIRQKMPLDDLDREDEVRLLKYLFTLIRAGMTEEAQRLCKRCGQAWRAATLEGWKLYHDPNVNGGTELEPVEGNPYRRIWKISCWRMAEDELFNRYERAIYAALSGNLKQLLPVCDTWEDTVWAYFRVMVDSLVEQEIQTSVATLDETEELPREYLGANWTLEKVFEELQATDKKRVLEENQEHYHIVQKFLILGDIDGLMDEFSKWLSKSRNNLPGHLLRFMTHLILFFRTLGLQTKEEVSIEVLKTYIQLLIREKHTNLIAFYTCHLPQDLAVAQYALFLESVTEFEQRHHCLELAKEADLDVATITKTVVENIRKKDNGEFSHHDLAPALDTGTTEEDRLKIDVIDWLVFDPAQRAEALKQGNAIMRKFLASKKHEAAKEVFVKIPQDSIAEIYNQCEEQGMESPLPAEDDNAIREHLCIRAYLEAHETFNEWFKHMNSVPQKPALIPQPTFTEKVAHEHKEKKYEMDFGIWKGHLDALTADVKEKMYNVLLFVDGGWMVDVREDAKEDHERTHQMVLLRKLCLPMLCFLLHTILHSTGQYQECLQLADMVSSERHKLYLVFSKEELRKLLQKLRESSLMLLDQGLDPLGYEIQL
What is the function of this protein?
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance (PubMed:12552102, PubMed:15229283, PubMed:30179222).  Required for the assembly of peripheral proteins into the NPC (PubMed:15229283, PubMed:12552102).  May anchor NUP62 to the NPC (PubMed:15229283).  Involved in nephrogenesis (PubMed:30179222).
What are the official names of this protein?
Nuclear pore complex protein Nup107, 107 kDa nucleoporin, Nucleoporin Nup107.
What is the protein family that this protein belongs to?
Belongs to the nucleoporin Nup84/Nup107 family.
What are the subcellular locations of this protein?
Nucleus membrane. Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the NPC core structure (PubMed:11564755). During mitosis, localizes to the kinetochores (PubMed:11564755). Dissociates from the dissasembled NPC structure late during prophase of mitosis (PubMed:11564755).
Protein: DMOA_HYPSL
Sequence: MKKRIVLNAFDMTCVSHQSAGTWRHPSSQAARYNDLEYWTNMAMELERGCFDCLFIADVVGVYDVYRGSAEMALRDADQVPVNDPFGAISAMAAVTEHVGFGVTAAITFEQPYLLARRLSTLDHLTKGRVAWNVVSSYLNSAALNIGMDQQLAHDERYEMADEYMEVMYKLWEGSWEDDAVKRDKKSGVFTDGSKVHPINHQGKYYKVPGFHICEPSPQRTPVIFQAGASGRGSKFAASNAEGMFILTTSVEQARQITTDIRNQAEAAGRSRDSIKIFMLLTVITGDSDEAAEAKYQEYLSYANPEGMLALYGGWTGIDFAKLDPDEPLQAMENDSLRTTLESLTHGENAKKWTVRDVIRERCIGGLGPVLVGGPQKVADELERWVDEGGVDGFNLAYAVTPGSVTDFIDYIVPELRKRGRAQDSYKPGSLRRKLIGTNDGRVESTHPAAQYRDAYVGKESVADRTQPSPFANAKAPVAE
What is the function of this protein?
Monooxygenase that mediates oxidation of dimethyl sulfide, the first step in dimethyl sulfide degradation pathway.  Has much lower activity with diethyl sulfide and other short-chain alkyl methyl sulfides.
What are the official names of this protein?
Dimethyl-sulfide monooxygenase, Dimethylsulfide monooxygenase large subunit.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family.
Protein: RDRP_IBDVB
Sequence: MSDVFNSPQARSTISAAFGIKPTAGQDVEELLIPKVWVPPEDPLASPSRLAKFLRENGYKVLQPRSLPENEEYETDQILPDLAWMRQIEGAVLKPTLSLPIGDQEYFPKYYPTHRPSKEKPNAYPPDIALLKQMIYLFLQVPEANEGLKDEVTLLTQNIRDKAYGSGTYMGQANRLVAMKEVATGRNPNKDPLKLGYTFESIAQLLDITLPVGPPGEDDKPWVPLTRVPSRMLVLTGDVDGDFEVEDYLPKINLKSSSGLPYVGRTKGETIGEMIAISNQFLRELSTLLKQGAGTKGSNKKKLLSMLSDYWYLSCGLLFPKAERYDKSTWLTKTRNIWSAPSPTHLMISMITWPVMSNSPNNVLNIEGCPSLYKFNPFRGGLNRIVEWILAPEEPKALVYADNIYIVHSNTWYSIDLEKGEANCTRQHMQAAMYYILTRGWSDNGDPMFNQTWATFAMNIAPALVVDSSCLIMNLQIKTYGQGSGNAATFINNHLLSTLVLDQWNLMRQPRPDSEEFKSIEDKLGINFKIERSIDDIRGKLRQLVLLAQPGYLSGGVEPEQSSPTVELDLLGWSATYSKDLGIYVPVLDKERLFCSAAYPKGVENKSLKSKVGIEQAYKVVRYEALRLVGGWNYPLLNKACKNNAGAARRHLEAKGFPLDEFLAEWSELSEFGEAFEGFNIKLTVTSESLAELNKPVPPKPPNVNRPVNTGGLKAVSNALKTGRYRNEAGLSGLVLLATARSRLQDAVKAKAEAEKLHKSKPDDPDADWFERSETLSDLLEKADIASKVAHSALVETSDALEAVQSTSVYTPKYPEVKNPQTASNPVVGLHLPAKRATGVQAALLGAGTSRPMGMEAPTRSKNAVKMAKRRQRQKESRQ
What is the function of this protein?
RNA-dependent RNA polymerase which is found both free and covalently attached to the genomic RNA.  May also contain guanylyl and methyl transferase activities (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, RDRP, Protein VP1.
What are the subcellular locations of this protein?
Virion. Note=Minor amounts are incorporated in the virion.
Protein: REPA_MSVRA
Sequence: MTSSSSNRQFLHRTANTFLTYPQCPEHPEIISQRIWDLVGRWNPLYIICAQEAHEDGNMHLHALIQTDKQVRTTDSRFFDIDGFHPNIQSAMSPNKVRDYILKEPLALFERGTFVPRKKTFLGNSSKGNSEKKPSKDEIMQDIISHATSKPEYLSMVRKSFPYDWATKLQYFEYSANKLFPDIQEEFINPHPTSEPDLLCNESIKDWLQPNIYQVSPQAYMLLQPNCYTVDDAISDLQWLDDLTSKQIMDQESRASTSSVQQGQENLLGPEA
What is the function of this protein?
Implicated in enhancement of V-sense gene expression.  Acts a an inhibitor of C-sense gene transcription (By similarity).
What are the official names of this protein?
Replication-associated protein A, RepA.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae Rep protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: XKR2_HUMAN
Sequence: MDRVYEIPEEPNVDPVSSLEEDVIRGANPRFTFPFSILFSTFLYCGEAASALYMVRIYRKNSETYWMTYTFSFFMFSSIMVQLTLIFVHRDLAKDKPLSLFMHLILLGPVIRCLEAMIKYLTLWKKEEQEEPYVSLTRKKMLIDGEEVLIEWEVGHSIRTLAMHRNAYKRMSQIQAFLGSVPQLTYQLYVSLISAEVPLGRVVLMVFSLVSVTYGATLCNMLAIQIKYDDYKIRLGPLEVLCITIWRTLEITSRLLILVLFSATLKLKAVPFLVLNFLIILFEPWIKFWRSGAQMPNNIEKNFSRVGTLVVLISVTILYAGINFSCWSALQLRLADRDLVDKGQNWGHMGLHYSVRLVENVIMVLVFKFFGVKVLLNYCHSLIALQLIIAYLISIGFMLLFFQYLHPLRSLFTHNVVDYLHCVCCHQHPRTRVENSEPPFETEARQSVV
What are the official names of this protein?
XK-related protein 2, Membrane protein XPLAC, X Kell blood group-related, X-linked.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SFMA_ECOLI
Sequence: MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
What is the function of this protein?
Part of the sfmACDHF fimbrial operon.  Could contribute to adhesion to various surfaces in specific environmental niches.  Increases adhesion to eukaryotic T24 bladder epithelial cells in the absence of fim genes.
What are the official names of this protein?
Uncharacterized fimbrial-like protein SfmA, Type-1A pilin.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: ODPB_RICBR
Sequence: MQITVREALRDAMQEEMIRDDKVFVMGEEVAEYQGAYKVTQGLLEQFGPKRVIDTPITEYGFAGLAVGAAFAGLRPIVEFMTFNFAMQAMDHIVNSAAKTHYMSGGQVRCPIVFRGPNGAASRVAAQHSQNYAACYSYIPGLKVVAPYSAEDHKGLMITAIRDDNPVIFLENEILYGHSFDISENVEPIPFGKAKVLKEGDSVTIVTFSIQVKLALDAANILQSDNINCEVIDLRTIKPLDIDTIIESVKKTGRLVVIEEGWFFAGIGATIAAIVMKEAFDYLDAPVEIVSGKDVPLPYAVNLEKLALPSEYDVINAVKKVCYIK
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit beta.