PharMolix/UniProtQA huggingface dataset:
Protein: IRAK3_HUMAN
Sequence: MAGNCGARGALSAHTLLFDLPPALLGELCAVLDSCDGALGWRGLAERLSSSWLDVRHIEKYVDQGKSGTRELLWSWAQKNKTIGDLLQVLQEMGHRRAIHLITNYGAVLSPSEKSYQEGGFPNILFKETANVTVDNVLIPEHNEKGILLKSSISFQNIIEGTRNFHKDFLIGEGEIFEVYRVEIQNLTYAVKLFKQEKKMQCKKHWKRFLSELEVLLLFHHPNILELAAYFTETEKFCLIYPYMRNGTLFDRLQCVGDTAPLPWHIRIGILIGISKAIHYLHNVQPCSVICGSISSANILLDDQFQPKLTDFAMAHFRSHLEHQSCTINMTSSSSKHLWYMPEEYIRQGKLSIKTDVYSFGIVIMEVLTGCRVVLDDPKHIQLRDLLRELMEKRGLDSCLSFLDKKVPPCPRNFSAKLFCLAGRCAATRAKLRPSMDEVLNTLESTQASLYFAEDPPTSLKSFRCPSPLFLENVPSIPVEDDESQNNNLLPSDEGLRIDRMTQKTPFECSQSEVMFLSLDKKPESKRNEEACNMPSSSCEESWFPKYIVPSQDLRPYKVNIDPSSEAPGHSCRSRPVESSCSSKFSWDEYEQYKKE
What is the function of this protein?
Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors (PubMed:10383454, PubMed:29686383).  Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex (By similarity).  Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells (PubMed:29686383).
What are the official names of this protein?
Interleukin-1 receptor-associated kinase 3, IRAK-3, IL-1 receptor-associated kinase M, IRAK-M, Inactive IL-1 receptor-associated kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In dendritic cells, translocates into the nucleus upon IL33 stimulation.
Protein: DNAK_LIMRD
Sequence: MASNKIIGIDLGTTNSAVAVMEGNEPKIITNPEGSRTTPSVVSFKNGETQVGEVAKRQAITNPNTISSIKSHMGEAGYTVEVDGKKYTPQEISAMILQYLKKYAEDYIGDTVTQAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTASSLAYGLDKKDKDEKILVYDLGGGTFDVSILELGDGVFQVLSTNGDTHLGGDDFDQKIMDWLIDGFKEEHGVDLSQDKMALQRLKDAAEKAKKDLSGVQEAQISLPFISAGENGPLHLEKTLSRAQFNQLTNDLVERTKQPVLNALKDADLTFDDIDEVILNGGSTRIPAVQEMVKELTGKEPNHSINPDEAVALGAAIQGGVLTGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSKSQIFSTAADNQPAVDIHVLQGERPMAADNKTLGNFQLTDIPAAPRGVPQIKVTFDIDKNGIVNVSAEDQGTHKKQNITIKSNSGLSDEEIERMKKDAEEHAEADKKKKEEVDLKNEVDQELFQVDKTLKEVKGKVPEDDIKKAESARDELKKAKESGNLDEMKAKKDALNKVIQDLSVKLYQQAQGAQGGAANGQPGDSQQNGNDNGNDDNTVDGDFKDVTPDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RRP4_AERPE
Sequence: MSSERQLAGRIVVPGEPLPEEVEASPPYVIDYKGVKRATVVGLLREKGDGGGRAFVKLKEIYVPQAGDVVIGLIQSVGIMNWFVDINSPYVAVLSVQDFLGRPFNPAVDDMQSLLKVGDYIKAKVVAFDKTRSPLLTVQGEGLGRIVRGKIVEISPAKVPRVIGRKMSMLKTLEEKTECKIFVARNGRIHLECPNEDLEAIAVMAIKIIDEEAYTSGLTKRIIKFIEEERRIREV
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Increases the RNA binding and the efficiency of RNA degradation.  Confers strong poly(A) specificity to the exosome.
What are the official names of this protein?
Exosome complex component Rrp4.
What is the protein family that this protein belongs to?
Belongs to the RRP4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC24_MYCTU
Sequence: MLSIDTNILLYAQNRDCPEHDAAAAFLVECAGRADVAVCELVLMELYQLLRNPTVVTRPLEGPEAAEVCQTFRRNRRWALLENAPVMNEVWVLAATPRIARRRLFDARLALTLRHHGVDEFATRNINGFTDFGFSRVWDPITSDG
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.  Its cognate antitoxin is VapB24 (By similarity).
What are the official names of this protein?
Ribonuclease VapC24, RNase VapC24, Toxin VapC24.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: ORF2_TTVA1
Sequence: MAEFSTPVRSGEATEGDLRVPRAGAEGEFTHRSQGAIRARDWPGYGQGSEKSMFIGRHYRKKRALSLCAVRTTKKACKLLIVMWTPPRNDQHYLNWQWYSSILSSHAAMCGCPDAVAHFNHLASVLRAPQNPPPPGPQRNLPLRRLPALPAAPEAPGDRAPWPMAGGAEGEDGGAGGDADHGGAAGGPEDADLLDAVAAAET
What are the official names of this protein?
Uncharacterized ORF2 protein.
Protein: PB1F2_I79A7
Sequence: MEQEQDTPWIQSTEHINIQKRESGQQTRKLEHPNSTQLMDHYLRIMNQVDMHKQTVSWKQWLFLKNPTQGSLKTRVLRRWKLFNKQGWTN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: ATPB_ECOSM
Sequence: MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UEPB_HORVU
Sequence: EKDCYHERDC
What are the official names of this protein?
Unknown endosperm protein B.
Protein: PAP9_ARATH
Sequence: MALIQHGSVSGTSAVRLSFSSSVSPPSSSPPLSRVSLNFQSEKKSCYRRMICRAMVQDSVQGIPSVYAREMERLSAKESLILAFNDAGGFEALVTGKITDMQKIDVNERITNLERLNPTPRPTTSPYLEGRWSFEWFGVNTPGSLAVRVMFERFPSTLVSLSNMEIFIKDNNTKATANIKLLNSIENKITLSSKLTIEGPLRMKEEYLEGLLESPTVIEEAVPDQLRGLLGQATTTLQQLPEPIKDTLANGLRIPLGGTYQRFFMISYLDDEILIVRDTAGVPEVLTRVETSSPMSSSSVVENLEYNS
What are the official names of this protein?
Probable plastid-lipid-associated protein 9, chloroplastic, Fibrillin-7a, AtPGL34.
What is the protein family that this protein belongs to?
Belongs to the PAP/fibrillin family.
What are the subcellular locations of this protein?
Plastid, chloroplast, plastoglobule.
Protein: PNP_ANAMF
Sequence: MFDITRKCVEWGDRLLVIESGKIARQADGAVVVDYGGTSVLSTVVSQKSKEPVDFLPLTVQFLAKSYAIGRIPGGFFKREGKPSDRETLISRLVDRSIRPLFPTGFCDEIVIVCNLLSYDQVSPPETVALIGAAAALAISGIPFPTPIAGAKIGYIREEERYILNPSAEELARSELDMFYSGTKSSVVMVESEASELSEEEMLGAVTFGHENCAQVLDLIEEFAEAAGPKDVVEFVPHDIGKVVSDISSGYSEKFSVAYSDHNKKPECSSLMPPGKACTQICAGKHVEESGEYTEQEVLLAIKTFERSLVRARVLDTLKRVDGRGFDQIRNIEIEVDLIPRSHGSALFTRGDTQALVITALGTPQDEQVVDGFDGDRRERFLLHYNFPSYAVGEAAALRPPGRREIGHGKLAWRAIHPVLPTKADFPYTIRVVSEITESDGSSSMATVCGASLALMDTGVPLKSSVAGIAMGLIKEGDRYAVLSDIIGDEDYLGDMDFKVAGTKDGITALQMDMKIRGIGFDIIEKSLQQAKDGRLFIIGKMDKVIKESREGVRDHVPRMESMIIDKNKIKNVIGTGGKNVREICEKTGVKIEISQDGTVMIYAVSRDAVEEAKNMIMCIVSEPEVGKVFSGVISEIAKYGAFVSFLGGRRGLVHISEIKNEHIGSVSDVLAVDDKVKVLVIGIDKDHVQLSMRRVDQDSGDLLEHESYSSNKKNGPQFGDASGGASGFRDYASGPARERRRSGGSGGRPVRRRSAGSSGSGSGGCYSVPQHVGTPDPVHGNDRRRGSGPQHASGGGGNKKPRFF
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_RICTY
Sequence: MKNKIKIRLKSFDHRSLDQATKEIVSAVKRTFATINGPIPLPRKIERFTVNRSPHVHKKSREQFEIRKHKRLLVIDDPNPAVVDALSKVDLAAGVDVVIELENGE
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SECB_SALPK
Sequence: MSEQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_COXBR
Sequence: MSTQLRAAEISDIIESRIEKFGIKAEERTEGTILNIKDGIVRVYGLRDVMFGEMVEFPENTYGLAFNLERDSVGAVVMGPYEHLEEGMTARCTGRILEVPVGEALLGRVVDGLGKPIDGKGPIDTSETSPIEKVAPGVITRKSVDTSLPTGLKSIDAMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKHTGVKCIYVAIGQKQSSVAAVVRKLEEHGAMEHTIVVNASASEAAALQYLAPYAGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAAHVNEAYVKEFTKGKVTGKTGSLTALPIIETQAGDVSAFIPTNVISITDGQIYLDVNLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLIGGLRIALAQYRELEAFSQFASDLDEATRKQLEHGQRVMEILKQPQYQPLSVGEMAIIWYVVNNNYLDQVELKKVVDFERSLLSFLRDQHQDLLDEINKNPNYSEKIIEKIKAVVEEFVKTQSY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMN_LISMH
Sequence: MEKSSIYGLTWTKLTEWLEAHGQKKFRATQVWDWLYRKRVKTFEEMSNVPKETIELLTANFVMNTLEEQVVQESTDGTTKYLFKLSDGNLIETVMMKQEYGLSVCVTTQVGCNIGCTFCASGLLKKSRDLTAGEIVEQIMNVQHYLDGRNLEERVSHVVVMGIGEPFDNYDNVMDFLRVINHDKGLAIGARHITVSTSGLAPRIIDFANEDFQVNLAISLHAPNNELRTSIMRINKTYSIEKLMEAIHYYVNKTNRRITFEYIMLKGVNDHKKEALELAALLGEHRHLAYVNLIPYNPVDEHIDYERSTKEDVLAFYDTLKKNGINCVIRREHGTDIDAACGQLRSKQIKRVGVRERMKQKQAAAEE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_KLULA
Sequence: MGIKNLATLISEQVPNAIKSRDIKYFHGRKVAIDASMSLYQFLIAVRQQDGVQLAGEDGETTSHLMGMFYRTLRMIDHGIKPCYVFDGSPPELKKYELDKRKVRREDTEAKLKEATEQAEIIKHERRLVKVLPWHNEEAQKLLSLMGIPYVVAPAEAEAQCAELAKSGKVFAAASEDMDTLCYQTPVLLRHLTFSEARKLPIQEFDTDVIYNTLDLTQTQFIDLGIILGCDYCEGIKGVGPVNALKLIKEHGSLEAIVEKFENGDISSGRWKIPEGWQFKEARDLFMQPDVIPSEEVTLKWEEPKAEELIEFMVKEKGFNEDRIKSGIERLRKGLKVGVQKRLDSFFKIQPKTKEELATAAKKAKDAKKKAAAKGKIAKRR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: RS17_SALEP
Sequence: MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKMHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CINAL_MYCLE
Sequence: MVVSARAGIVVTGTEILTGRVRDRNGPWLADRLLELGVKLAHITICGDCPADIEAQLRFMAEAGVDLIVTSGGLGPTADDMTVEVVARFCNREMVLDVELENKIAAILNSLMTRFNPGDFEAVRAANRKQAMIPAGSQVLDPIGTAPGLVVPGKPTVMVLPGPPSELQPMWRRAVMTAATREAIADRTIYRQQTLRMFGLSESGLAETLRDAQASIPGFDALEITTCLRRGEIEMVTRYEPDVVNVYVELTQLLRDRHGHQLYSEDGARVDDLIAHLLAGRRIATAESCTAGLLAARLTERPGSSDYVAGALVAYSNEAKVTLLGVDPALIAEHGEVSEPVVEAMAAGALQRFDVDTAAAISGIAGPGGGTAEKPIGTVCFTVMLADGGPTLTRTLRLPGNRSDIRERSTTVAMHLLRHALSDTDSVP
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RSPO2_XENLA
Sequence: MQFQLFSFALIILNCVDYSHCQASRWRRSKRASYGTNPICKGCLSCSKDNGCLRCQPKLFFFLRREGMRQYGECLQSCPPGYYGVRGPDMNRCSRCRIENCDSCFSRDFCIKCKSGFYSLKGQCFEECPEGFAPLDDTMVCVDGCEVGPWSEWGTCSRNNRTCGFKWGLETRTRQIVKKPAKDTIPCPTIAESRRCKMAIRHCPGGKRTTKKKDKRNKKKKKKLLERAQEQHSVVLATDRSSQ
What is the function of this protein?
Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors.  Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway (By similarity).  Activates neural markers and promotes muscle formation.  Overexpression blocks activin, nodal and BMP4 signaling, suggesting that it may negatively regulate the TGF-beta pathway (PubMed:15469841).  During embryonic development, plays a crucial role in limb specification, amplifying the Wnt signaling pathway independently of LGR4-6 receptors, possibly by acting as a direct antagonistic ligand to RNF43 and ZNRF3, hence governing the number of limbs an embryo should form (By similarity).
What are the official names of this protein?
R-spondin-2, Roof plate-specific spondin-2, XRspo2.
What is the protein family that this protein belongs to?
Belongs to the R-spondin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL32_BURVG
Sequence: MAVQQNKKSPSKRGMHRSHDFLTAAPLAVEPSTGEVHLRHHVSPNGYYRGKKVVKTKND
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CH10_MYCLE
Sequence: MAKVKIKPLEDKILVQAGEAETMTPSGLVIPENAKEKPQEGTVVAVGPGRWDEDGAKRIPVDVSEGDIVIYSKYGGTEIKYNGEEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa antigen, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETFB_ANAPI
Sequence: MRIYVCVKQVPDTSGKVAVNPDGTLNRASMAAIINPDDMSAIEQALKLKDETGCQVTALTMGPPPAEGMLREIIAMGADDGVLISAREFGGSDTFATSQIISAAIHKLGLSNEDMIFCGRQAIDGDTAQVGPQIAEKLSIPQVTYGAGIKKSGDLVLVKRMLEDGYMMIEVETPCLITCIQDKAVKPRYMTLNGIMECYSKPLLVLDYEALKDEPLIELDTIGLKGSPTNIFKSFTPPQKGVGVMLQGTDKEKVEDLVDKLMQKHVI
What is the function of this protein?
Part of the ETF-acryloyl-CoA reductase complex involved in the pathway of L-alanine fermentation.  The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for acryloyl-CoA reductase.
What are the official names of this protein?
Acryloyl-CoA reductase electron transfer subunit gamma, Electron transfer flavoprotein small subunit, ETFSS, Electron transfer flavoprotein subunit gamma, Gamma-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF beta-subunit/FixA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_CAUVC
Sequence: MARYNPKDTEPKWREAWAKADVFKTGEINDGRPKYYVLEMFPYPSGRIHMGHVRNYAMGDVVARYKRAQGFNVLHPMGWDAFGMPAENAAMERGVHPKGWTYDNIAAMREQLKSLGISVDWSREFATCDPEYYGKQQAWFLRLLKRGLVYRKEASVNWDPVDMTVLANEQVIDGKGWRSGAVVEKRKLTQWFLRITDYADALIDGLKTLDRWPDKVRLMQENWIGRSKGLRFKFQFDGEAPDGMAEGLEVYTTRPDTLFGASFVGIAPEHPLAEQLAAANPQIQTFIADCRKGGTSEAEIESAEKLGYDTGLRVKHPLDPSITLPVWIANFILMDYGTGAIFACPAHDQRDLDFARKYDLPVLPVVLPNGEDPATFTVGKEAYVGPGKIFNSKFLDGLDVEAAKAEAIARIEAANQGQGATVYRLRDWGVSRQRYWGCPIPVIHCEACGVVPVPEDQLPVALPDDVTFDKPGNPLLRHPTWRHTTCPSCGGKAERETDTLDTFIDSSWYFARFADTQAAEPVGKDAADHWLPVDQYIGGVEHAILHLLYARFITRALKDEGLLSVEEPFAGLFTQGMVTHEAYKNEAGEWVEPSDVVITTEGSTRTAKHAKTGAPIIIGDIEKMSKSKKNVVAPEDIFEAYGVDSARLFVMSDSPPERDVQWTNSGVEGSWRFTHRLWNEFDSQPAGDFAHDDSDEAALALRKAAHKLIGFVTDSIEGFRFNSGVARLYEFLNALKAAPAEGASQAVLAARAEALNILARLVAPFTPHLAEEAWARMGGEGMVVDAPWPKADPALAADDERVLPIQINGKRRGEIKVKAGAPDDEVTKIALADPNVMAHLEGLTVRKVIVVKDRIVNIVAN
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_EXIS2
Sequence: MAREFSLKNTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWKGNRVNIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYSVGTLRDRLQANAHAIQIPIGAEDEFKGIIDLVEKKTYMYGNDLGTDIEETEGFPAEFAEEAEELRASLIEAVADYEEEMMMKYLEGEEITIEELKAGIRKATLTVDFYPVLVGSAFKNKGVQLMLDAVLDYLPSPVDVKAITGINMDTDEEIVRESTDEAPFSALAFKVMTDPYVGKLTFFRVYSGTASAGSYVKNSTKGKRERLGRILQMHANSREEIPMVFAGDIAAAVGLKDTTTGDTLCAEKDNVVLESMTFPEPVISVAIEPKTKADQDKMGQALAKLAEEDPTFRTETNPETGQTIISGMGELHLDIIVDRMRREFKVEANVGAPQVAYRETIRQSAKIDSKFARQSGGRGQYGHVVVEFEPNEEGAGFEFNNKIVGGVVPREYIPAVEHGIEEALQNGILAGYPVVDVKAALVFGSYHDVDSNEMAFKIAASMAVKQLKDKSGAVILEPMMKVEIVIPDEYMGDIMGDVTSRRGRVEGMEARGNAQVVRSMIPLSEMFGYATGLRSRTQGRGTYSMHFDHYEEVPKSVAEEIIKKANG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_MICDP
Sequence: MSVVSSVTVTVPATTANLGPGFDCIGAALTLYNKVKFTRLDAGGLIIHVTGKEAEGVNTDESNLLYQAFVKLYQHIEQIPPSVKIEIDLGVPLARGLGSSATAIVGGLVAANQLAGEPLSQLQVMELAIAMEGHPDNVVPALLGGCRLAATSAEGWEICDVPWDENVVPVVAIPDFELSTQEARRVLPTEFSRADAIFNTAHLGLLLRGLATGKGEWLKTALQDKLHQPYRKALIPGYDAVNQAAVAAGAYGMVISGAGPTLLALADAQNSQAVAAAMQTAWQTVGITADVRSLSLDNQGASSLNEG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH_MYCGE
Sequence: MKKRNKGLVEQTTTEKNNFSRKTAWKVFWWVIILAVVIGVLAYIFSPRAATAVVESWKLNGGSNSTLTAKVSGFSNELTFKQINGSTYVTDTILQVSITFDGLNSPLTVTAHKTVNSNGNVIFNIANLSINQSNGQITVNSNGTMMNGGSSNNTKSIAGFETLGTFIAPDTRARDVLNGLFGLLPIIIFVVFFLLFWRSARGISAGGREEDNIFSIGKTQAKLAKSTVKFTNIAGLQEEKHELLEIVDYLKNPLKYAQMGARSPRGVILYGPPGTGKTLLAKAVAGEAGVPFFQSTGSGFEDMLVGVGAKRVRDLFNKAKKAAPCIIFIDEIDSVGSKRGRVELSSYSVVEQTLNQLLAEMDGFTSRTGVVVMAATNRLDVLDDALLRPGRFDRHIQINLPDIKEREGILKVHAENKNLSSKISLLDVAKRTPGFSGAQLENVINEATLLAVRDNRTTININDIDEAIDRVIAGPAKKSRVISDEDRKLVAYHEAGHALVGLHVHSNDEVQKITIIPRGQAGGYTLSTPKSGDLNLKRKSDLLAMIATAMGGRAAEEEIYGNLEITTGASSDFYKATNIARAMVTQLGMSKLGQVQYVPSQGTLPSNVKLYSEQTAKDIDNEINFIIEEQYKKAKTIIKSNRKELELLVEALLIAETILKSDIDFIHKNTKLPPEILLQKQEQQAKQKLNKSEVKPESETNS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: DAPE_ENT38
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALMIERLRAIGFTVERMDFGDTQNFWAWRGQGETLAFAGHTDVVPAGDADRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPNHKNRLAFLITSDEEASAKNGTVRVVETLMERHERLDYCLVGEPSSTEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPMLNELVNIEWDKGNEFFPPTSMQIANLQAGTGSNNVIPGDFSVQFNFRFSTELTDEMIKSRVVALLEKYELRYSVDWWLSGQPFLTQRGKLVDAVVNAIAHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.