PharMolix/UniProtQA huggingface dataset:
Protein: IF4A_PICGU
Sequence: MSQEFNEIDANTIETNYDNVVYSFDDLNLKPNIVRGIFGYGYESPSAIQQRAILPITEGRDVLAQAQSGTGKTATFTISALQRIDENLKATQALILAPTRELALQIQNVITHIGLYLNVTVHASIGGTSMKDDIEAFKSGVQIVVGTPGRVFDMIERRFFRTDKVKMFIMDEADEMLSSGFKEQIYNIFRLLPETTQVVLLSATMPQDVLEVTTKFMNNPVRILVKKDELTLEGIKQFYINVEQEDFKFDCLCDLYDSISVTQAVIFCNTRSKVEFLTTKLKAENFTVSAIHADLPQSDRDTIMNEFRSGSSRILIATDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTDEDVGMMREIEKFYSTQIEEMPANIGELFN
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase eIF4A, Eukaryotic initiation factor 4A, eIF-4A, Translation initiation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_ANADE
Sequence: MDKIVIEGGVPLRGSVDVSGAKNAALPVIAAALLAEGEHEVRNVPDLADVRTLGKLLGHMGCEVVRGEGDRRTVRLRVPAAVTPEAPYELVKTMRASVLVLGPLLARLGRARVSLPGGCAIGARPIDQHLKALTALGAEIRLEHGYVNASVPGGRLRGTVFTFDAQTVTGTENVMMAAALAEGETVLRNCAREPEVKDLGDALVAMGALVEGAGTDEIWIEGVPSLRPLSHAVIPDRIEAGTFLVAGALPGNDVTVRGCVAAHQEALVEKLRAVGAEVTKVEGGLRVIGDGRPRPVDVRTAPHPGFPTDMQAQLMVLLCLADGTSRITETVFENRFMHVQELIRLGAHVEVDGRVAMVKGVPELSGAPVMASDLRASAALVLAGLAATGTTEVLRVYHLDRGYERIEEKLAPLGARIRRVRG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_CHLCH
Sequence: MPIITRLPDSVANKISAGEVVQRPASVVKELLENAIDAGATKISVTIKDAGKELIRIADNGVGMNRDDALLCVERFATSKIKSADDLDALHTLGFRGEALASICSVSHFELKTRQADATLGLLFRYDGGSLVEELEVQAEQGTSFSVRNLFYNVPARRKFLKSNATEYHHLFEIVKSFTLAYPEIEWRMVNDDEELFNFKNNDVLERLNFYYGDDFASSLIEVAEQNDYLPIHGYLGKPALQKKRKLEQYFFINRRLVQNRMLLQAVQQAYGDLLVERQTPFVLLFLTIDPSRIDVNVHPAKLEIRFDDERQVRSMFYPVIKRAVQLHDFSTNISVIEPFASASEPFVGSSSQPIFSSTSSQAPRMGGGSRRFDLSDAPERAITKNELYRNYREGAFSSPSVASYDAPSPLQQGGLFALASAEESLFGAQAVHEASENIEAFQLSPLDNIVEHKEVEPKIWQLHNKYLICQIKTGLMIIDQHVAHERVLYERALEVMQQNVPNAQQLLFPQKVEFRAWEYEVFEEIRDDLYRLGFNVRLFGNRTVMIEGVPQDVKSGSEVTILQDMITQYQENATKLKLERRDNLAKSYSCRNAIMTGQKLSMEEMRSLIDNLFATREPYTCPHGRPIIIKLSLDQLDKMFGRK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RKD1_ARATH
Sequence: MKSFCKLEYDQVFGKENNSFSFLNHSSLYSHQSELANPFFELEDEMLPSATSSNCFTSASSFLALPDLEPISIVSHEADILSVYGSASWTAEETMFVSDFAKKSETTTTKKRRCREECFSSCSVSKTLSKETISLYFYMPITQAARELNIGLTLLKKRCRELGIKRWPHRKLMSLQKLISNVKELEKMEGEENEDKLRNALEKLEKEKKTIEKLPDLKFEDKTKRLRQACFKANHKRKRRSGMSTPITSSSSSASASSSSYSSVSGFER
What is the function of this protein?
Putative transcription factor.
What are the official names of this protein?
Protein RKD1, AtRKD1, RWP-RK domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: U76E4_ARATH
Sequence: MEKRVEKRRIVLVPVAAQGHVTPMMQLGKALQSKGFLITVAQRQFNQIGSSLQHFPGFDFVTIPESLPQSESKKLGPAEYLMNLNKTSEASFKECISQLSMQQGNDIACIIYDKLMYFCEAAAKEFKIPSVIFSTSSATIQVCYCVLSELSAEKFLIDMKDPEKQDKVLEGLHPLRYKDLPTSGFGPLEPLLEMCREVVNKRTASAVIINTASCLESLSLSWLQQELGIPVYPLGPLHITASSPGPSLLQEDMSCIEWLNKQKPRSVIYISLGTKAHMETKEMLEMAWGLLNSNQPFLWVIRPGSVAGFEWIELLPEEVIKMVTERGYIAKWAPQIEVLGHPAVGGFWSHCGWNSTLESIVEGVPMICRPLQGEQKLNAMYIESVWKIGIQLEGEVEREGVERAVKRLIIDEEGAAMRERALDLKEKLNASVRSGGSSYNALDELVKFLNTE
What are the official names of this protein?
UDP-glycosyltransferase 76E4.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: P2C74_ORYSJ
Sequence: MACMLCCSPLPALSSPATGGAAVVGFSSSSRRKAAHVHPAVAVKDHDLSSSSPAACGDEGGGAVVIEEEAHPSMMMSVAAPAMKKKAVAARWRPPRLVVPAVAGADEAMAAAAAVKAAKEKEEEEAMEVEGEGFWVASRRGLRHAMEDGYGVITHKIEGHSQMAFYGVYDGHGGRAAVDFVAGRLGNNVVAAAEKQRLSEKASSPAAADHVAAAIRAAYLATDSEFLSQGTRGGACAATALVIDGDLYVANLGDCRAVISRHGAAAALTSDHTPARDDERSRIESSGGYVSCGSNGVWRVQDCLAVTRSFGDGGLKRWVVAEPEVSRTPLAGAGCEFLVIASDGLWNKVSNQEAVDAVAAGHYSVDSCRRLVDMARRRGSRDDVTVMVVDLKRFLNC
What are the official names of this protein?
Probable protein phosphatase 2C 74, OsPP2C74.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: UVRA_VIBVU
Sequence: MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEVYDYLRLLYARVGEPRCPEHQVPLAAQTISQMVDKVLELPEGAKMMLLAPIVKERKGEHVKTLENLAAQGFIRARIDGETCDLTDPPTLELHKKHTIEVVVDRVKVRGDLQQRLAESFETALELSGGIAVIAPMEGDGEEIVFSANFACPHCGYSMQELEPRLFSFNNPAGACGTCDGLGVQQYFDPERVIQDANLSLAQGAIRGWDQKNYYYFQMLTSLAEHYDFDLHAPFNSLSKRIQEVILKGSGRTEIEFKYINDRGDIRLKRHPFEGILNTLERRYRDTESNSVREELVKYISTKPCTSCGGTRLRLEARNVFINDTTLPQIVELSIADALTFFATLKLEGQRAQIAEKVMKEINDRLQFLVNVGLNYLNLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLKTLTHLRDLGNTVLVVEHDEDAIRCADHVIDIGPGAGVHGGQVVAEGTMAEILANPDSLTGQYLSGAKQIIVPTQRTPRDKNKTVELIGASGNNLKEVNLSVPVGLFSCITGVSGSGKSTLINDTFFKIAHTQLNGATTAQPAPYKSIKGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPIRELFSGTQESRSRGYKPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCDVCKGKRYNRETLEVHYKGKSIDEVLEMTVEDAHEFFAPVPVIARKLQTLMDVGLSYIRLGQAATTLSGGEAQRVKLARELSKRDTGKTLYILDEPTTGLHFHDIQQLLTVLHRLRDHGNTVVVIEHNLDVIKTADWIIDLGPEGGQGGGEIIAQGTPEDVAQIEGSHTARFLKPMLK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDB1_XENLA
Sequence: MSYNYVVTAQKPTAVNACVTGHFTSEDDLNLLIAKNTRLEIYVVTPEGLRPVKEVGMYGKIAVMELFRPKGESKDLLFILTAKYNACILEYKQSGDSIDIITRAHGNVQDRIGRPSETGIIGIIDPDCRMIGLRLYDGLFKVIPLERDNKELKAFNIRLEELHVIDVKFLYSCQAPTICFVYQDPQGRHVKTYEVSLREKEFSKGPWKQENVEAEASMVIAVPEPFGGAIIIGQESITYHNGDKYLAIAPPIIKQSTIVCHNRVDVNGSRYLLGDMEGRLFMLLLEKEEQMDGSVTLKDLRVELLGETSIAECLTYLDNGVVFVGSRLGDSQLVKLTTESNEQGSYVVVMETFTNLGPIVDMCVVDLERQGQGQLVTCSGAFKEGSLRIIRNGIGIHEHASIDLPGIKGLWPLRVAADRDTDDTLVLSFVGQTRVLTLTGEEVEETDLAGFVDDQQTFFCGNVAHQQLIQITSASVRLVSQNPQNLVSEWKEPQGRKVSVCSCNSRQVLLAVGRVLYYLEIHPGELRQTSCTEMEHEVACLDVTPLGGNDTLSSLCAIGLWTDISARILSLPGFQLLHKEMLGGEIIPRSILMTSFESSHYLLCALGDGALFYFSLNTDTGLLSDRKKVTLGTQPTVLRTFRSLSTTNVFACSDRPTVIYSSNHKLVFSNVNLKEVNYMCPLNSEGYPDSLALANNSTLTIGTIDEIQKLHIRTVPLFESPRKICYQEVSQCFGVLSSRIEVQDASGGSSPLRPSASTQALSSSVSCSKLFSGSTSPHETSFGEEVEVHNLLIIDQHTFEVLHTHQFLQNEYTLSLVSCKLGKDPTTYFVVGTAMVYPDEAEPKQGRIVVFQYNDGKLQTVAEKEVKGAVYSMVEFNGKLLASINSTVRLYEWTAEKELRTECNHYNNIMALYLKTKGDFILVGDLMRSVLLLAYKPMEGNFEEIARDFNPNWMSAVEILDDDNFLGAENAFNLFVCQKDSAATTDEERQHLQEVGLFHLGEFVNVFCHGSLVMQNLGETSPPTQGSVLFGTVNGMIGLVTSLSESWYNLLLDVQNRLNKVIKSVGKIEHSFWRSFHTERKTEPATGFIDGDLIESFLDISRPKMQEVIANLQIDDGSGMKRETTVDDLIKVVEELTRIH
What is the function of this protein?
Protein, which is both involved in DNA repair and protein ubiquitination, as part of the UV-DDB complex and DCX (DDB1-CUL4-X-box) complexes, respectively.  Core component of the UV-DDB complex (UV-damaged DNA-binding protein complex), a complex that recognizes UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair.  The UV-DDB complex may recognize UV-induced DNA damage and recruit proteins of the nucleotide excision repair pathway (the NER pathway) to initiate DNA repair (By similarity).  Also functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  The functional specificity of the DCX E3 ubiquitin-protein ligase complex is determined by the variable substrate recognition component recruited by DDB1.  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
DNA damage-binding protein 1, Damage-specific DNA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the DDB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS18_ACIC1
Sequence: MTKAPARKPKKKVCVFCKEGITYVDYKDTNLLRKFISDRGKIRARRVTGNCAQHQRDVATAIKNSREMALLPYTNAAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: EDL13_ARATH
Sequence: MGDEPLLQKVKIQEDIESVPLLQKVKIQEDIESVKGIRVNNDGEEDGPVTLILLFTTFTALCGTFSYGTAAGFTSPAQTGIMAGLNLSLAEFSFFGAVLTIGGLVGAAMSGKLADVFGRRGALGVSNSFCMAGWLMIAFSQATWSLDIGRLFLGVAAGVASYVVPVYIVEIAPKKVRGTFSAINSLVMCASVAVTYLLGSVISWQKLALISTVPCVFEFVGLFFIPESPRWLSRNGRVKESEVSLQRLRGNNTDITKEAAEIKKYMDNLQEFKEDGFFDLFNPRYSRVVTVGIGLLVLQQLGGLSGYTFYLSSIFKKSGFPNNVGVMMASVVQSVTSVLGIVIVDKYGRRSLLTVATIMMCLGSLITGLSFLFQSYGLLEHYTPISTFMGVLVFLTSITIGIGGIPWVMISEMTPINIKGSAGTLCNLTSWSSNWFVSYTFNFLFQWSSSGVFFIYTMISGVGILFVMKMVPETRGRSLEEIQAAITR
What is the function of this protein?
Sugar transporter.
What are the official names of this protein?
Putative sugar transporter ERD6-like 13.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: URK_CHLAD
Sequence: MQFNPIIIGVAGGSASGKTSVAQAILQRVGADRIAHIDHDRYYKDLSHLPLEERARFNFDHPDALDNDLLVAHLDALCAGQAVDLPTYDYATYVRLPYTERIEPRPVILVEGILIFYEPVLRRRMHIKLFVDTDADLRFIRRLRRDIAERGRSVESVIEQYLATVRPMHLEFVEPTKRYADVIFPGGGRNPIAIDMVVARIEAALQSMA
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METJ_VIBC1
Sequence: MADWNGEYISPYAEHGKKSEQVKKITVSIPLKVLKVLTDERTRRQINNLRHATNSELLCEAFLHAYTGQPLPTDEDLRKDRPDDIPTEAKALMTAMGIEFEAFDEE
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_POLSJ
Sequence: MKFVDEAFIDIAAGDGGSGCVSFSHEKYKEFGGPNGGDGGRGGHVYAVADVNLNTLVDFRFSRRHEARNGQHGMGSDMFGAKGDDIILKMPVGTILTDAETGEVLFELLVPGEQVLIAKGGDGGFGNLRFKSSTNRAPRSKTPGWPGERKNLKLELKVLADVGLLGMPNAGKSTFISAVSNARPRIADYPFTTLHPNLGVVRVGPEQSFVVADLPGLIEGASEGAGLGHLFLRHLQRTRLLLHIVDLAPFDEGVDPVAQAKAIVRELKKYDEALYEKPRWLVLNKLDMVDADKRAAIVKDFVKRFKFKGPVFEISALTREGCEHLIKTIYQHVKQVQKSEQPVEEVDPRFVPLPPESPETP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCL2_ASPTN
Sequence: MISWIRTLGALLLLASVAQAQFQFFEHMFGNGGHQQQRSQNVPSDSARYQSMWDSAQCDKYLCPGTLACVHFPHHCPCPHPDVEEKVELGEGSAVCVSRGGYRQGEASRKIELARKGLL
What is the function of this protein?
Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway.
What are the official names of this protein?
Long chronological lifespan protein 2.
What is the protein family that this protein belongs to?
Belongs to the LCL2 family.
Protein: MALT_ECO24
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREDTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: IORF_CVBOK
Sequence: MASLSGPISPTNLEMFKPGVEELNPSKLLLLSNHQEGMLYPTILGSLELLSFKRERSLNLQRDKVCLLHQESQLLKLRGTGTDTTDVPLKQPMATSVNCCHDGIFTILEQDRMPKTSMAPTLTESSGSLVTRLMSIPRLTFSIGTQVAMRLFRLGFRLARYSLRVTILKAQEGLLLIPDLLHAHPVEPLVQDRAVEPILAIEPLPLV
What is the function of this protein?
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host.
What are the official names of this protein?
Protein I, Accessory protein N2, N internal ORF protein, IORF, Protein in nucleocapsid ORF.
What is the protein family that this protein belongs to?
Belongs to the coronavirus I protein family.
What are the subcellular locations of this protein?
Virion.
Protein: MRAY_THEPX
Sequence: MLQKIILATVVAFVLSLASGPLFIPYLRKLKFGQKVREDGPKSHIKKSGTPTMGGIMFITATVISTLIFSHWNKYLAILLLGFLGYGLIGFADDFLKVYFKRPLGLKAREKLIGQFLLAIIISYFAQEYVGTEVIFPFLKTTIDLGNFYIPFIVFVIVGTVNSVNLTDGLDGLAAGVSFIVMAFFTMTALFLNNITYGAFSAALTGGLLGFLRYNRHPAEIFMGDTGSLAIGGAIATAAVLTKLPLILPLIGIIYVAEAFSVIIQVLSFKLFGKRVFKMSPLHHHFELSGWQEQNVVYAFWIVTLIAMFLSFYSLS
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TYSY_AERHH
Sequence: MRAYLDLMQKILDEGTVKSDRTGTGTISLFGHQMRFNLAEGFPLVTTKKCHLRSIIHELLWFLNGDTNTAYLKEHGVSIWDEWADENGDLGPVYGAQWRSWPAADGSVIDQIQKAVDDIKHNPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTHMMAQQCDLEVGDFVWTGGDVHLYSNHMEQTALQLTREPRPLPTLVIKRKPDSIFDYKFEDFEIEGYDPHPGIKAPVAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_NITWN
Sequence: MPEIGVRNGAFGADKFGLQNLKAVYWNPGAPQLYEHALRSGEAMVNADGALCAETGIFTGRSPKDKFTVRDAATDKSVWWAGNQSMTPDQFAALYSDFLAHARNMTLFAQDLYGGADPNFRIKTRVFTELAWHSLFIRTLLRRPETSELAAFVPELTVIDLPSFRADPQRHGVRSENVVAIDFTRRIILIGGSHYAGEMKKSIFTTLNYYLPDQDVLPMHCSANVGPGGDSAIFFGLSGTGKTTLSADPGRTLIGDDEHGWSKDGIFNFEGGCYAKCIRLSREAEPEIYAASKRFGAVLENVVHDEVTRVPDFNDGSKTENTRSAYPLEFIPNASLTGCAGQPKNLVMLAADAFGVLPPIARLTPAQAMYHFLSGYTAKVAGTERDLGNEPQPEFSACFGSPFLPRHPGVYGNMLRALIAKHNVDCWLVNTGWTGGKYGTGRRMPIKVTRALLGAALDGSLRGVPFHDDRYFGFAVPTSVPGVEPHILDPIRTWADKIEFDRTARALIGMFRQNFTKFENDVDAEVREAAPGTMMAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VMLR_BACSU
Sequence: MKEIVTLTNVSYEVKDQTVFKHVNASVQQGDIIGIIGKNGAGKSTLLHLIHNDLAPAQGQILRKDIKLALVEQETAAYSFADQTPAEKKLLEKWHVPLRDFHQLSGGEKLKARLAKGLSEDADLLLLDEPTNHLDEKSLQFLIQQLKHYNGTVILVSHDRYFLDEAATKIWSLEDQTLIEFKGNYSGYMKFREKKRLTQQREYEKQQKMVERIEAQMNGLASWSEKAHAQSTKKEGFKEYHRVKAKRTDAQIKSKQKRLEKELEKAKAEPVTPEYTVRFSIDTTHKTGKRFLEVQNVTKAFGERTLFKNANFTIQHGEKVAIIGPNGSGKTTLLNIILGQETAEGSVWVSPSANIGYLTQEVFDLPLEQTPEELFENETFKARGHVQNLMRHLGFTAAQWTEPIKHMSMGERVKIKLMAYILEEKDVLILDEPTNHLDLPSREQLEETLSQYSGTLLAVSHDRYFLEKTTNSKLVISNNGIEKQLNDVPSERNEREELRLKLETERQEVLGKLSFMTPNDKGYKELDQAFNELTKRIKELDHQDKKD
What is the function of this protein?
Recognizes and binds in the vacant E-site of ribosomes stalled by some peptidyltransferase center (PTC)-targeting antibiotics.  Makes contact with the PTC and both ribosomal subunits.  Induces conformational changes in the P-site, which allows it to dislodge the antibiotic from its PTC binding site.  Binds to ribosomes either directly following translation initation or subsequent to E tRNA release during elongation (PubMed:30126986).  Involved in resistance to a narrow spectrum of antibiotics (the streptogramin A antibiotic virginiamycin M, the lincosamide antibiotic lincomycin and the pleuromutilin antibiotic tiamulin) (PubMed:16109936, PubMed:30126986).
What are the official names of this protein?
Ribosome protection protein VmlR, Multidrug resistance system ATP-binding protein VmlR.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. ARE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Does not stably associate with ribosomes.
Protein: ZRAS_ECOLI
Sequence: MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRASEADRQALLEKGNVLIRALESGSRVGMGMRMHHVQQQALLEEMAGQPGVLWFAVTDAQGIIILHSDPDKVGRALYSPDEMQKLKPEENSRWRLLGKTETTPALEVYRLFQPMSAPWRHGMHNMPRCNGKAVPQVDAQQAIFIAVDASDLVATQSGEKRNTLIILFALATVLLASVLSFFWYRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGSTFTLWLPVNITRKDPQG
What is the function of this protein?
Member of the two-component regulatory system ZraS/ZraR.  May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium.
What are the official names of this protein?
Sensor protein ZraS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APAG_EDWI9
Sequence: MIDAPRIIVQVQSVYAGSQSLPEEARFVFAYTVTLRNLGRFNVQLLRRYWLITNGNGRQTEVQGEGVIGEQPLIQPNGEFQYTSGAIIETPCGTMEGHYEMVDHQGHTFRIAIPVFRLAIPSLIN
What are the official names of this protein?
Protein ApaG.
Protein: CRGB_CANLF
Sequence: MGKITFYEDRGFQGRCYECSSDCPNLQPYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRRGDYPDYQQWLGFSDSIRSCRLIPQHSGTFRMRIYERDDFRGQMSEITDDCLSLQDRFHLNEIHSLNVLDGCWVLYEMPSYRGRQYLLRPGEYRRYLDWGAMNAKVGSLRRVMDFY
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin B, Gamma-B-crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: SINL6_ARATH
Sequence: MVGVLLSERNGSQKRHCSSISSDDGRKRVDKTRSAMLTDLDILDCPICYQALKIPVFQCGNGHLACSSCCPKLRNKCPACALPVGHIRCRAMERVLESVLVPCRYADLGCTKTIYYGRESTHEKICNFSPCSCPVQGCNYTGSYKDLYEHYDLTHSTGSTAYSFNGVSYIAAMMFISDKILIERVYEKKLLFVVQCFEEPCGVYVSVSCIAPSAPEVGEFSYGLLYTTWEGVTMTYQSPKVKKVLKVSSQRPKDSFMLIPHSLLCGPLLGMMLCINELKQM
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  It probably triggers the ubiquitin-mediated degradation of different substrates.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase SINA-like 6, RING-type E3 ubiquitin transferase SINA-like 6, Seven in absentia-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.