PharMolix/UniProtQA huggingface dataset:
Protein: STXB2_HUMAN
Sequence: MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKRREPIPSLEAIYLLSPTEKSVQALIKDFQGTPTFTYKAAHIFFTDTCPEPLFSELGRSRLAKVVKTLKEIHLAFLPYEAQVFSLDAPHSTYNLYCPFRAEERTRQLEVLAQQIATLCATLQEYPAIRYRKGPEDTAQLAHAVLAKLNAFKADTPSLGEGPEKTRSQLLIMDRAADPVSPLLHELTFQAMAYDLLDIEQDTYRYETTGLSEAREKAVLLDEDDDLWVELRHMHIADVSKKVTELLRTFCESKRLTTDKANIKDLSQILKKMPQYQKELNKYSTHLHLADDCMKHFKGSVEKLCSVEQDLAMGSDAEGEKIKDSMKLIVPVLLDAAVPAYDKIRVLLLYILLRNGVSEENLAKLIQHANVQAHSSLIRNLEQLGGTVTNPGGSGTSSRLEPRERMEPTYQLSRWTPVIKDVMEDAVEDRLDRNLWPFVSDPAPTASSQAAVSARFGHWHKNKAGIEARAGPRLIVYVMGGVAMSEMRAAYEVTRATEGKWEVLIGSSHILTPTRFLDDLKALDKKLEDIALP
What is the function of this protein?
Involved in intracellular vesicle trafficking and vesicle fusion with membranes.  Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion.  Regulates cytotoxic granule exocytosis in natural killer (NK) cells.
What are the official names of this protein?
Syntaxin-binding protein 2, Protein unc-18 homolog 2, Unc18-2, Protein unc-18 homolog B, Unc-18B.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: ATPE_NITOC
Sequence: MAMTMHVDIVSAEREIFSGTVNMLFAPAEMGEVGIMPRHTPLITRLKPGEVRLQRPEGQEDFFYVSGGLLEVQPHVVTVLADTAQRAADIDEAAALAAKQRAEEALQDREGKLDYARAQAELAEAIAQLKAIQRIRKKLG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1636_MYCTU
Sequence: MSAYKTVVVGTDGSDSSMRAVDRAAQIAGADAKLIIASAYLPQHEDARAADILKDESYKVTGTAPIYEILHDAKERAHNAGAKNVEERPIVGAPVDALVNLADEEKADLLVVGNVGLSTIAGRLLGSVPANVSRRAKVDVLIVHTT
What are the official names of this protein?
Universal stress protein Rv1636, USP Rv1636.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: NADK_SULIL
Sequence: MRVKIVSKPTSQLNNIIEKIKNISTKLGFEVVDKDFDYVIAVGGDGTLLRAVKQNKPVIAVKAGRRGLLMDVPVDKFEEALLRLKKGDYEEEEYMLLEMIYNDKVELGFNEVGILYDRPEAIKVGISFDTERVSVEGDGVLVSTPQGSSGWGMSATNSLLYKDLSAIEIIFVNPIFYYLRSVVIPPKPLTLRLEDKGYPQTARAVVDGEVVTLIKTNQEITVRVSQRKAKILRFFKLDLIGEVLHAYHI
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_ROTPC
Sequence: MDYDTLASKYLKFVYDFEDVTYQNNYFVTDEYKSDLEQYLKSIHDGEKISQSKIDSMETALLTKVPKEKRCLISKLVFAYGKHGNVENKLLKYGTKDALTHAIQKDVKPYENNIITSEIFKDESEYTDTYMDPAINTSCQSNCQAMMFTISEMKLTDIKNATRLEKLFTIVAATINKYGMPRHNIRYRYEWETMKDKPYHLAAWINSSIEMIACVVDHHTYMIARELIVKSFTNRTSLAKLVSSPMTVLTAMLPIRGTVITTENLELEYSSKSVNYLISEEMAEDFMKAIEQLRDEGLEIYQDYYEKWFKSPDPLTFPNIALIYSFSFHVGYRKQALSDAVYDQITVTYDDNVNMEMYKEYSERIENEIFTILKDKVVHEDKRLEEYELSALLSMSSASNGVLREIDFGGQKVRSTKKNMHVIDDMYHKRYTTDIPPVDERNPIPLGRRDVPGRRTRAIFILPYQYFIAQHSFAEMMLKYAKREREYSEFYSQANQVLSYGDVTRYLDSNSILCFTDVSQWDASQHNTRVLRRSIIRAMERLKQLTHNTNIHKAIDIYIQSQKNLENSYVLIDKKAIQYGATASGEKQTKIMNSIANKALIQTVLGKLMTDYTFDVKMIRVDGDDNYAIVRFPTAITEKLLSEFTSKLRSYYSEMNVKVKALASLTGCEIAKRYIAGGMLFFRAGVNILNHEKRNQDSAYDMAATLYANYIVNALRGLTMSRTFILVKICQMTSIKITGTLRLFPMKSILALNSTFKVFDEVDYVINYPISELFIQLQRKLSSIKAKSKIADNIAKSPQFKSYVEFLNKSLTADENPIVSDGIKLTEKAKLNSYAPIALEKRRDQFNMMVSFLQNPTTFKSETVVTINDVLYFISGFIKINSSVALPKEENNTMPLLPVTIKRTLNYFGLRTHDYDIKGSSSTMSKIIKQYSVYTPGIEELYEVVNKSIDSIRGYFASFNVPKADVDTYISTQMYKHDRFKILQAYIYNLLSVNYGMYQLVDLNSAKFFDHVIHTPMAKTPTAVFMIDLALRLKVINHCIEKGEVITVSVHANKTDYLKLWRMLWNVKTMNSPYSKNSMFDE
What is the function of this protein?
RNA-directed RNA polymerase that is involved in both transcription and genome replication.  Together with VP3 capping enzyme, forms an enzyme complex positioned near the channels situated at each of the five-fold vertices of the core.  Following infection, the outermost layer of the virus is lost, leaving a double-layered particle (DLP) made up of the core and VP6 shell.  VP1 then catalyzes the transcription of fully conservative plus-strand genomic RNAs that are extruded through the DLP's channels into the cytoplasm where they function as mRNAs for translation of viral proteins.  One copy of each of the viral (+)RNAs is also recruited during core assembly, together with newly synthesized polymerase complexes and VP2.  The polymerase of these novo-formed particles catalyzes the synthesis of complementary minus-strands leading to dsDNA formation.  To do so, the polymerase specifically recognizes conserved 3' sequence(s) in plus-strand RNA templates.  Once dsRNA synthesis is complete, the polymerase switches to the transcriptional mode, thus providing secondary transcription (By similarity).
What are the official names of this protein?
RNA-directed RNA polymerase, Protein VP1.
What is the protein family that this protein belongs to?
Belongs to the reoviridae RNA-directed RNA polymerase family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging (By similarity).
Protein: FDL16_ARATH
Sequence: MNCDRICELPDSLLTQVLSYLPTIDSVKTSVLSKRWEFLWLRVPVLDLKVSDFPDENYASFIDNFLEFNRKSRMRKFKLKYDEYTYDDDRLAGWVVTTVDRGIQHLDAKGFETNMCVREFMPQNIYKCNTLVSLMLVTVGIENPEFVVSLPSLKIMHLEDVWYYDDPLIMEKIISGCPVLEDFVLIRPIDFCNLDVLQFLRVRSLSLRSFRLTFEYSVSCTYFSVEIDAPRLEYLNFNDDQSDTIVVKNMTSLSMIDIDSEFNVKFGGSRLEPGDLRKRDIIRDFLTAISCVRHMIISRRTLEVLDRYSKLVPIPKFDNLYRLQAAVSRSMLQLLLVFLESCPNLENLILDFTVSTEPEQDGLTYVPQCLLSSLECVEIRELIMGEETGEKLVRYFLKNSVVLKKLILRLEDSSIANQDSDIFKELSTFTKRSRSCEVIIIH
What are the official names of this protein?
F-box/FBD/LRR-repeat protein At2g26030.
Protein: ACCO_TOBAC
Sequence: MENFPIINLEKLNGSERADTMEMIKDACENWGFFELVNHGIPHEVMDTVEKMTKGHYKKCMEQRFKELVASKGLEAVQAEVTDLDWESTFFLRHLPVSNICEVPDLDDQYREVMRDFAKRLEKLAEELLDLLCENLGLEKGYLKKIFYGTKGPNFGSKVSNYPPCPKPDLIKGLRAHTDAGGIILLFQDDKVTGLQLLKDGQWIDVPPMRLSIVVNLGDQLEVITNGKYKSVMHRVITQTDGTRMSLASFYNPGSDAVIFPAPTLVEKEAEESKAIYPKFVFDDYMKLYAGLKFQAKEPRFEAMIKAMETVKSDPVATA
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase, ACC oxidase, Ethylene-forming enzyme, EFE.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PEPT_SHIFL
Sequence: MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVILEGMEKAVQVIVRIAELTAQRK
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_HALH5
Sequence: MCGIVGYIGTEDAKEILLKGLEKLEYRGYDSAGIAVATEEGVHIFKEKGRIATLREVVDQGVKSTVGIGHTRWATHGEPSKVNAHPHQSESSRFTIVHNGVIENYEQLKRDYLQAVTLQSDTDTEVVVQLVERFVHEGQSVEAAFRHTLSLLKGSYAIALLDKKDTDTIYVGKNKSPLLVGVQDGVNVVASDAMAMLQVTDQFLEIMDEEIVIVTKDDVTIKTLDGTAVSREPYTAELDASDIEKGTYPHFMLKEIDEQPFVIRNIIQKYQNEDGSVRLDEDIRQAVMEADRIYIIAAGTSYHAGLVGKQLIENFAKQPVEVHIASEFLYNMPLLSKRPLFIFISQSGETADSRGVLVEVKKLGYKALTITNVPGSTLSREADFTLHTHAGPEIAVASTKAYTAQMAVLTLLAADTAKAKGIDLGFDPIQELSIVANAMETLCNQKETLEKIARDYLAVTRNCFFIGRATDYFVCLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPIVALATQEHVNLSIRGNVKEVAARGAFPCIISMEGLNEEDDTFVLPKVHSHLTPLVSVIPLQLIAYYAALHRGCDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
Protein: TRMD_MESH7
Sequence: MKINILTLFPRYFEVFCRESIIGKAIKQKKITINVVNFRDFSKNKHKKVDDYVYGGGPGLLLQIQPVVDALEKVGGLKIALSPQGQKFDQSVARKLAKEDEITILCGHYEGFDQRIIDNFIDFELSLGDFILTGGEIAAMAIIDAIIRLKPDIINPESLKNETFNDFLLDFPQYSRPANFRGLEVPKVLISGNHREIGEWRQEQRELITKKKRPDLWEKFLKIKNKK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_RHOPB
Sequence: MIEKVPMTAGGYAALEVELKQRQSVDRPRIIEHIAEARSHGDLSENAEYHAAKEEQSHNEGRIAELEDKLARADIIDISKLSGDTIKFGATVTLIDEDTEKKAVWQIVGEPEADAKKGRISITSPLARALIGKKKGASVEVVAPGGAKAYEITKVEWR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: BIOF_METEP
Sequence: MSPNPSNSLDAFAGEKLAGLEASALRRRLAVTARGPEAAAERGGRSLVSFSCNDYLGLAHDPRVIAAATEALARYGAGAGASRLVTGNSPPLAALEERLARHKGKEAALVFGSGYLANLGIAPALVGAGDLILIDELGHSCLFAGAAMSRAQTVRFAHNDVAQLRTLLAEHRGTARRALILTERVFSMDGDRAPLPEILALAGEYDAWTLVDDAHGLGVVEPGQRAPLEMGTLSKTLGSYGGYLCASQPVIDLLTSRARSLVYTTGLPPASAAAALTALDIVETEPERAARPLALARRFTARLGLPEAMSPIVPVLIGAAEAALALSTALEARGFLVVAIRPPTVAPGTARLRVAFSAAHDEGQVDALAEALIELAPESVRAG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SYP_HELPG
Sequence: MLFSKLFAPTLKEPPKDAVLKSHKHLAQAGYIYQVGSGIYNFLPLAKKVLDKIENITHKRMQEHGAQNILMSFVVLASLWEKSGRLDKYGKELLVFKDRKDNDFVLSPTLEENITEIAANFIKSYKQLPVHLYQIHTKFRDEIRPRFGLVRAREFIMKDGYSFHEDAESLDKEFLNTQSAYKEILSDLGLDFRIVEADSGAIGGSKSREFVVLTECGEDTIVVCQNCDYAANIEIAKRSKRPEPLNVPKAQLAKFPTPNTTSAQSVAEFFKTEPYFVLKALVKKVIHKDKETLACFFVRGDDNLEETKALNALNIIGANALELREANEEDLNHAGLIAGFIGPYGLKKHVSYIIFDEDLKEGDCLIAGANEKDFHAVGVDLKGFENLVYADIVQIKESDHCPNCQGALKYHKSLEVGHIFKLGQGYAKSLKASFLDKNGKEQFFEMGCYGIGISRLLSAILEQKSDDLGCVWTKNTAPFDVVIVVSNWKDEAQKKLAFEVYERLLQKGVDALLDDRDARFGAKMRDFELIGERLALIVGKQALESKEFECIKRANLEKQTLKDTELEEKILEMLASE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM2_ARATH
Sequence: METDLNDYTVIKEGEAEILMHKKNQVFFNKAQVNNRDMSIAVLREFLSKRKQEHEAKSSKRTRPASKVIEKDASEASKEETPSENGMNNGDHEVASEDGPSSVSKDPAKTTERFAPREPKPPKVLEALSASGLRALRYAREIEGIGQVVALDNDLASVEACQRNIKFNGSVAISKVESHHTDARVHMLTHPKEFDVVDLDPYGSPSIFLDSAIQSVTDGGLLMCTATDMAVLCGGNGEVCYSKYGSYPLRAKYCHEMALRILLASIESHANRYKRYIVPVLSVQMDFYVRVFVRVYTSASAMKNTPLKLSYVYQCIGCDSFHLQPVGRSLPKNNSVRYLPAIGPVVKQDCNHCGKKYNMGGPIWSAPMHDPEWVTSILNSVKSMKDRYPAYDRISAVLTTVSEELLDVPLFLSLHNLCATLKCISPSAAMFRSAVINANYRISGTHVNPLGMKTDAPMEVIWDIMRCWVKNHPIKAQSPEQPGSVILSKEPSHEVDFSRHIGSLSKAQAKKVARFLPNPEKHWGPKLRAGRQITSKHVSLIGHEAVNGHLSQHHEELKEEDEEAEPEDNVQDKVDPKRQKTATDNITST
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of most tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase 2, tRNA 2,2-dimethylguanosine-26 methyltransferase 2, tRNA(guanine-26,N(2)-N(2)) methyltransferase 2, tRNA(m(2,2)G26)dimethyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: GLPK_SOLUE
Sequence: MSNYIGAIDQGTTSTRFIVFDHGGRIVSVAQKEHEQIFPQPGWVEHDANEIWRRTREVIAEALEKRALSASDLAAIGITNQRETTVVWDRLSGEPVYNALVWQDTRTAAAVAELARDGGADRFRAQTGLPLATYFSALKIGWILDNVPAVRARAEAGDILFGNIDTFLLWNLTGGLHLTDCTNASRTHLMNLQTLDWDDELLAAFRIPRAMLPRIVSSSEVYGNATLASVAGVPIAGILGDQQAALVGQTCFHAGEAKNTYGTGCFLLMNTGTKPTPSKHGMLTTVAYRFATQPAVYALEGSVAITGALVQWVRDNFGLIEKSSDIEVLARTVKDNGGVYFVPAFSGLYAPYWKDNARGVIAGLTRYTNKGHLARAVLEATAFQTREVVEAMEKDSAIALETLRTDGGMVSNDLLMQFQSDILDRPVVRPAVQETTALGAAYAAGLAVGFFQDTDDLRSRWSVDHTWKPQMEPERRQELYSFWKKAVTRSFDWL
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: ATPL_MYCGA
Sequence: MNIFLVIHELINQADQVNVTLTNHVGAYIGAGMAMTAAAGVGVGQGFASGLCATALARNPELLPKIQLFWIVGSAIAESSAIYGLIIAFILIFVAR
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: M4K1_HUMAN
Sequence: MDVVDPDIFNRDPRDHYDLLQRLGGGTYGEVFKARDKVSGDLVALKMVKMEPDDDVSTLQKEILILKTCRHANIVAYHGSYLWLQKLWICMEFCGAGSLQDIYQVTGSLSELQISYVCREVLQGLAYLHSQKKIHRDIKGANILINDAGEVRLADFGISAQIGATLARRLSFIGTPYWMAPEVAAVALKGGYNELCDIWSLGITAIELAELQPPLFDVHPLRVLFLMTKSGYQPPRLKEKGKWSAAFHNFIKVTLTKSPKKRPSATKMLSHQLVSQPGLNRGLILDLLDKLKNPGKGPSIGDIEDEEPELPPAIPRRIRSTHRSSSLGIPDADCCRRHMEFRKLRGMETRPPANTARLQPPRDLRSSSPRKQLSESSDDDYDDVDIPTPAEDTPPPLPPKPKFRSPSDEGPGSMGDDGQLSPGVLVRCASGPPPNSPRPGPPPSTSSPHLTAHSEPSLWNPPSRELDKPPLLPPKKEKMKRKGCALLVKLFNGCPLRIHSTAAWTHPSTKDQHLLLGAEEGIFILNRNDQEATLEMLFPSRTTWVYSINNVLMSLSGKTPHLYSHSILGLLERKETRAGNPIAHISPHRLLARKNMVSTKIQDTKGCRACCVAEGASSGGPFLCGALETSVVLLQWYQPMNKFLLVRQVLFPLPTPLSVFALLTGPGSELPAVCIGVSPGRPGKSVLFHTVRFGALSCWLGEMSTEHRGPVQVTQVEEDMVMVLMDGSVKLVTPEGSPVRGLRTPEIPMTEAVEAVAMVGGQLQAFWKHGVQVWALGSDQLLQELRDPTLTFRLLGSPRLECSGTISPHCNLLLPGSSNSPASASRVAGITGL
What is the function of this protein?
Serine/threonine-protein kinase, which may play a role in the response to environmental stress (PubMed:24362026).  Appears to act upstream of the JUN N-terminal pathway (PubMed:8824585).  May play a role in hematopoietic lineage decisions and growth regulation (PubMed:8824585, PubMed:24362026).  Able to autophosphorylate (PubMed:8824585).  Together with CLNK, it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase kinase 1, Hematopoietic progenitor kinase, MAPK/ERK kinase kinase kinase 1, MEK kinase kinase 1, MEKKK 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: Y324_PERMH
Sequence: MIITTTDFIEGKKIRDYKGVVSKEAVIGVNIIRDVFAKVRDIVGGRSAAYEKELTNARNQILEELKEEARNLGANAVIGINFSYEMYQSMLLVSVWGTAVVVE
What are the official names of this protein?
UPF0145 protein PERMA_0324.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: SYCC_DROME
Sequence: MSKRGQPAWQAPEAVDRPKLKLFNSLTRQKEDFVPLDGNNVTWYSCGPTVYDASHMGHARSYISFDILRRILSDYFGYNIHYVMNITDIDDKIIRRARQNHLFDEYAAEAQKLPLDELLGQQKEVLQRFQDTCAKNTDPDKKIMLDKTLQRMNDAVEALTKAVGKGDEREISEKRLLYLNEAKDPISDWLDSLKGAQINDNAVFEALPRYWEDQFHNDMKSLNILPPDVLTRVSEYVPQIVTFIQKIIDNGLAYAANNSVYFDVNGFDKREKHHYAKLVPEAYGDTKSLQEGEGDLSIAEDRLSEKRSANDFALWKASKAGEPWWDSPWGKGRPGWHIECSAMASDIFGPTFDIHTGGVDLKFPHHDNELAQSEAAFNESEWVKYFLHTGHLTIAGCKMSKSLKNFVTIQEALKKHSATQLRLAFLLHSWKDTLDYSENTMEMATQYEKFLNEFFLNVKDLTRHVLSEEPRRQFDAWTEVEAALQKKFSNAQVQVHASLCDNIDTRSALDAIRELVSVSNVYIRDNKTRLNSLLLRNVATYITDLLHVFGAISGPRGGIGFPVSGGSGAQAAGADLETTVLPYVQSLAEFRYLVREQAKTLKAFDILKLCDDLRDNVLPNLGVRLEDKDIGKYAVKLVDRDSLLREREAKLAAEAEKAAEKERKKQAAAEAAAAKEAQRRVNPKEMFLAETEKYSAFDENGLPTHDKEGKEVSKGQIKKLQKLQQQQEQRYNEYLASIEKA
What are the official names of this protein?
Cysteine--tRNA ligase, cytoplasmic, Cysteinyl-tRNA synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BUCBP
Sequence: MAHVKRGVIARARHKKVLKQAKGYYGARSRTYRTARQAIIKAGQYSYRDRRQRKRYFRKLWITRINAAVRENQISYSKFMYGLKKASIAVDRKMLSELAIFDNVSFCSLIKSSKDALTSIELNKNL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RLMI_ECO57
Sequence: MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVDHQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFSRRLQQAQKWRDWLAQKDGLDSYRLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVAVRKKEGMELTQGLVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRYVENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFVRDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOGL3_ARATH
Sequence: MATSSSSYGIEQLQKGCYYEWMSVQAKHIVDLKEALMSHRSKEDHKLEELVGKIVNDFQKYTEKRSELSRRSCSSYFAPSWNSPLENGLLWMGGCRPSSFIRVIYSLCGSQAETQLSQYLLKIDENVEVNHGGSMSDLNASQLAKINDLHIKVIEKEDKITKKSANLQENVADMPIAIAAYATDLMNGDVVVEDALDKYEEGMAVLMVEADKLRFETLRKIVDVVTPVQAAEFLLAGKRLHISLHEWGRVREEQRFGCVRTDAAAATGGAGTEKSKRSSLLM
What are the official names of this protein?
Protein DOG1-like 3.
Protein: KTHY1_SULTO
Sequence: MPRFISFEGIDGAGKTTLAKKVYEVLKKKGYNVILTQEPFTREITELIKKAGWNDPVLLTLLFSADRAFHIKWIMEQKPEIVLMDRYFHSTIAYQSVLGLDEKWIEEVNSKFPKPDIVFLLDIKVNEAIKRIRKDDQFNFEEKIATLEAVRKKYLELARKYNFIVLDAMSKIEELTEKTVQIICSLVKCS
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TPPC5_MOUSE
Sequence: MEARFTRGKSALLERALVRPRTEVSLSAFALLFSELVQHCQSRVFSVAELQARLAALGRQVGARVLDALVAREKGARRETKVLGALLFVKGAVWKALFGKEADKLEQANDDARTFYIIEREPLINTYISVPKENSTLNCASFTAGIVEAVLTHSGFPAKVTAHWHKGTTLMIKFEEAVIARDRALEGR
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: CAPP_HAES1
Sequence: MPQKYSTLKNNINMLGHFLGETISDAQGSDILDLIENIRVLSRDSRSGDEKAREKLLDTLSTISNENIIPVARAFSQFLNLTNIAEQYQTISRKHIDQVASDRSLEALFERLKAQNVPAEKVISTVEKLLIELVLTAHPTEVTRRSLLHKYVEINRCLSRLEHDDLTQSESTKLKRRLMQLIALAWHTNEIRTQRPTPVDEAKWGIAVIENSLWKAVPDFCRQLNLHLEKNFGVQHSVNLAPVKFSSWIGGDRDGNPFVTAETTRQVLIMNRWKAAELFLADIQVLSEELSVVHCTEEFRAKYGDHLEPYRVVVKNLRAKLVKTVAYYGEILENKPSTINTNDILTDDQQLWEPLYDCYQSLHQCGMRIIANGILLDCLRRIRCFGLSLSHLDIRQESLRHTKALSEITRYIGLGDYSQWMEDDKQAFLIRELSSRRPLLPRNWTPSLETQEILETCRVIAQQPEGVISCYIISMARTASDVLAVHLLLKEAGVTYYLPVVPLFETLDDLNASKEVMTQLFNVGWYRGVINNKQMVMIGYSDSAKDAGMMAASWAQYRAQEQLVNLCEKMGVELTLFHGRGGTIGRGGAPAHAALLSQPPRSLKNGLRVTEQGEMIRFKLGLPAVAVNSFDLYASAILEANLLPPPEPKESWRAIMNELSDSSCNIYRSVVRGDKDFVPYFRSATPEQELSKLPLGSRPSKRNPNGGVESLRAIPWIFAWMQNRLMLPAWLGASASIRQSIEKGNKETIEEMCKNWPFFSTRIGMLEMVFSKTDTWLSEHYDLNLVKKELWYLGQSLREQLQADIKTILSLSHEDELMSDLPWIAESIALRNIYTDPLNLLQVELLRRLRENPENPNPDVEQALMITITGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: IKBF1_MDBVW
Sequence: MMEEVGTAGNNLGATEIDHDEQNTFLRICRTGSIYELMEVTPFFGGDRHLLHRYDRHGRQCIHTVAWHDRANAVMKIEILMQSGVNINAKELGTGNTLLHIAASTGNYLLADWFCQQLGVDLGASNNQQETAYYIAYKMRDRKMMKLLRAHGVAYNNTLSAGLL
What is the function of this protein?
Suppresses the host immune response through NF-kappa-B inactivation.  Possesses ankyrin repeat domains required for NF-kappa-B binding but lacks the regulatory regions required for dissociation from NF-kappa-B and degradation.  Therefore, prevents host NF-kappa-B release and subsequent activation (By similarity).
What are the official names of this protein?
I-Kappa-B like protein F1.
What is the protein family that this protein belongs to?
Belongs to the polydnaviridae I-Kappa-B-like protein family.
Protein: EX7S_HAEIG
Sequence: MARKPASSQDFETTLAKLENIVAHLENGDLPLEEALKEFEQGVQLAKLGQERLQQAEQRIQILLQKTEDAPLNDYKGNA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.