PharMolix/UniProtQA huggingface dataset:
Protein: CYB_EUBGL
Sequence: MTNIRKTHPLMKIINDAFIDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTTTAFSSITHICRDVNYGWIIRYLHANGASMFFICLYAHMGRGLYYGSYAFQETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAIVHLLFLHETGSNNPTGIPSNMDKIPFHPYYTIKDILGALLLILTLLMLTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILAFIPMLHTSKQRSMMFRPFSQFLFWVLVADLLTLTWIGGQPVEHPYMIVGQFASILYFLLILVLMPTASLIENKLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARMT1_YEAST
Sequence: MTIPGRFMTIDKGTFGEYTASTRWPIIIQNAIDDLSKHQETEKSNGTKFEQGEVIKKELKEFRQEIIDRVPLRPFTEEEIKIANVPLSFNEYLKKHPEVNWGAVEWLFSEVYLYRRVNVLFQRQCEWAKFDIFNRLKQSTFESSFYGVVELALRYENLLPQLREMKQNPGNEIDDILKVLFKEFIEISLWGNATDLSLLTNATLEDIKSIQGAKARAASESKIVVNDTEKAWEVLTKARADANSREIRVDFVLDNSGFELYADLMLAAFLLQSGLATKCIFHAKDIPYMVSDVMLKDFDILVHDLRDREFFPSGEPSTKESRALDLFAGEMEKFVSSGKIEFREDSFWTTELDYWNLDANETKYHGSILHKDLQKSNLVIFKGDLNYRKLTGDRKWPRTTKWETAIGPLATNGITSLSLRTCKADVQVALPEGLDAKLSQEWEKENPGRGSWWCCSGKWAVICFCSGIHK
What is the function of this protein?
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate (PubMed:27322068).  Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism (PubMed:27322068).
What are the official names of this protein?
Damage-control phosphatase YMR027W, Sugar phosphate phosphatase YMR027W.
What is the protein family that this protein belongs to?
Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
Protein: RLMB_VIBVY
Sequence: MSNEFIYGIHAVRAVLDKEPERFIEAYVLKGRQDDRLMPILNELQMVGVSLQQMTRKTLDDKAHGANHQGIIARVKPAKQLNENDLDDILAKHASPLLLILDGVTDPHNLGACLRNADAAGVAAVIVPKDKSAPMTATVSKVACGAAETVPLVRVTNLARTMRHLQEQGIWIVGTAGEATHDIYQAKLTGSLAIVMGAEGDGMRRLTRETCDDLIKIPMAGAVSSLNVSVASGICLFEAVRQRLASQ
What is the function of this protein?
Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
What are the official names of this protein?
23S rRNA (guanosine-2'-O-)-methyltransferase RlmB, 23S rRNA (guanosine2251 2'-O)-methyltransferase, 23S rRNA Gm2251 2'-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCPI_SABMA
Sequence: ISVCDLPADRGQCTAYIPQWFFNKTTEDCEKFVYGGCQGNANRFETKDDCIANCGCNLPSKVGPCRVSARMWFHNPETEKCEVFIYGGCHGNANRFATETECQEVCDRYQKPGFCYQPSETGPCKGSFPRYYYDYEDGECKEFIYGGCEGNANNFETKESCENAC
What is the function of this protein?
Potent inhibitor of pancreatic carboxypeptidase A with a Ki of 27 nM, and of the serine proteases trypsin, chymotrypsin and pancreatic elastase, with Ki values of 6. 9 nM, 1. 83 nM and 4 nM, respectively.  Does not inhibit cysteine and aspartic proteases.
What are the official names of this protein?
Carboxypeptidase inhibitor SmCI.
Protein: LEXA_ACET2
Sequence: MQNKINEKQQKILDFLNEQIEKNGYPPSVREICNAVGFKSTSTVHSYLEKLRKQGLIQKDPSKPRALKVINNKKNSKTDEPKNIYSGKELVEVPIIGKVTAGQPILAVENIEDTFPLPLDFVQNSTVFMLRVQGDSMIEAGIFDNDYIVVKQQSTANNGDIVVALIDDEATVKTFYKEKGFIRLQPANKFYDPIIVRDNLSILGKVIGVFRKM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y296_BUCBP
Sequence: MTKCNIFNMIFLKFSNAFIKKIKYLSIISIISVFLLNSSIVYSCSKIILIFDNNFKENNKNILNKLVLPIKNIILKGTSNLEFNDYLLKLSNFYGSPIHKCIYNFPYKKLQNNNLNNLKYIIFKSKIDNNFIKNMQYLNVSNDNIDNVVRCIKLELKIHQLKQDHKCNILIQNNSFLKHNIVQKNIILSFEIPYNTKNIYGFFTKKNKFFDVHGISSAPIFLKFPFLKKYRISSKFNPNRFNPITKKNSPHQGIDFAMPIGTPILSIGDGVILNAKFSIQAGNYITIQHNCSYITKYMHLKKILVKIGDKVKMRDKIGLSGNTGYSTGPHLHYEVWLHKKVINPKNLKTRECLIKKNLKEHINFSNIIITQFEIFK
What are the official names of this protein?
Uncharacterized metalloprotease bbp_296.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23B family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RECR_GEOKA
Sequence: MHYPEPLSKLIDSFMKLPGIGPKTAARLAFHVLAMKEDTVLEFAKALVDVKRHIHYCTICGHITDTDPCYICKDERRDRTTICVVQDPKDVIAMERMKEYNGLYHVLHGAISPMEGIGPEDIKIAELLTRLQDETVQEVILATDPNIEGEATAMYISRLLKPTGIKVTRIAHGLPVGGDLEYADEVTLSKALEGRREL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PYRB_PSEU2
Sequence: MTPLDAKRPLQLNHLGQLRHFLSLDGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLSADVITLNVSTSSTSKGETLFDTLRNLEAMAADMFVVRHADSGAAHFIAEHVCPDVAIINGGDGRHAHPTQGMLDMLTIRRHKGGFENLSVAIVGDILHSRVARSNMLALKALGCPDIRVIGPKTLLPVGVEQYGVKVYTDLNEGLKDVDVVIMLRLQRERMTGGLLPSEGEFYRLFGLTTARLAAAKPDAIVMHPGPINRGVEIESAVADGAHSVILNQVTYGIAIRMAVLSMAMSGQNAQRQFEQENAQ
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: AQR1_YEAST
Sequence: MSRSNSIYTEDIEMYPTHNEQHLTREYTKPDGQTKSEKLNFEGAYINSHGTLSKTTTREIEGDLDSETSSHSSDDKVDPTQQITAETKAPYTLLSYGQKWGMVAILTMCGFWSSLGSPIYYPALRQLEKQFNVDENMVNVTVVVYLLFQGISPTVSGGLADCFGRRPIILAGMLIYVIASIGLACAPSYGVIIFLRCIQSIGISPTIAISSGVVGDFTLKHERGTFVGATSGFVLLGQCFGSLIGAVLTARWDWRAIFWFLTIGCGSCFLIAFLILPETKRTIAGNLSIKPKRFINRAPIFLLGPVRRRFKYDNPDYETLDPTIPKLDLSSAGKILVLPEIILSLFPSGLLFAMWTLMLSSISSGLSVAPYNYHLVIIGVCYLPGGIGGLMGSFFTGRIIDMYFKRKIKKFEQDKANGLIPQDAEINMFKVRLVCLLPQNFLAVVAYLLFGWSIDKGWRIESILITSFVCSYCAMSTLSTSTTLLVDLYPTKSSTASSCFNFVRCSLSTIFMGCFAKMKAAMTVGGTFTFLCALVFFFNFLMFIPMKYGMKWREDRLLKQQRQSWLNTLAVKAKKGTKRDQNDNHN
What is the function of this protein?
Probable transporter that confers resistance to short-chain monocarboxylic acids and quinidine.
What are the official names of this protein?
Probable transporter AQR1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: RL35_LACLS
Sequence: MPKQKTHRASAKRFKRTGNGGLKRFRAYTSHRFHGKSVKQRRQLRKASMVSKGDFKRIRRMVATMK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL6_COREF
Sequence: MSRIGKNPIAIPSGVEVKIDGRLVDVKGPKGNLNVTLPEPITASIENNEILVTRPDDHRNSRSMHGLSRSLVNNLVVGVTEGYTIKMEIFGVGYRVALKGKNLEFSLGYSHPVLIEAPEGITFAVDGTTKLSISGIDKQKVGQVAAVIRRLRKDDPYKGKGIRYEGEQIRRKVGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: USPB_PECAS
Sequence: MISTFALFWALCIVCIINMARYYSSLRVLLMILRDCDPLLYQYVDGGGFFTSHGQPSKQIRLVGYIYAQRYLDHHDPEFIRRCERVRGQFLLTTALCGLIVISLIAMMMWY
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ILVD_SHIBS
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELAARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: RNZ2_HUMAN
Sequence: MWALCSLLRSAAGRTMSQGRTISQAPARRERPRKDPLRHLRTREKRGPSGCSGGPNTVYLQVVAAGSRDSGAALYVFSEFNRYLFNCGEGVQRLMQEHKLKVARLDNIFLTRMHWSNVGGLSGMILTLKETGLPKCVLSGPPQLEKYLEAIKIFSGPLKGIELAVRPHSAPEYEDETMTVYQIPIHSEQRRGKHQPWQSPERPLSRLSPERSSDSESNENEPHLPHGVSQRRGVRDSSLVVAFICKLHLKRGNFLVLKAKEMGLPVGTAAIAPIIAAVKDGKSITHEGREILAEELCTPPDPGAAFVVVECPDESFIQPICENATFQRYQGKADAPVALVVHMAPASVLVDSRYQQWMERFGPDTQHLVLNENCASVHNLRSHKIQTQLNLIHPDIFPLLTSFRCKKEGPTLSVPMVQGECLLKYQLRPRREWQRDAIITCNPEEFIVEALQLPNFQQSVQEYRRSAQDGPAPAEKRSQYPEIIFLGTGSAIPMKIRNVSATLVNISPDTSLLLDCGEGTFGQLCRHYGDQVDRVLGTLAAVFVSHLHADHHTGLPSILLQRERALASLGKPLHPLLVVAPNQLKAWLQQYHNQCQEVLHHISMIPAKCLQEGAEISSPAVERLISSLLRTCDLEEFQTCLVRHCKHAFGCALVHTSGWKVVYSGDTMPCEALVRMGKDATLLIHEATLEDGLEEEAVEKTHSTTSQAISVGMRMNAEFIMLNHFSQRYAKVPLFSPNFSEKVGVAFDHMKVCFGDFPTMPKLIPPLKALFAGDIEEMEERREKRELRQVRAALLSRELAGGLEDGEPQQKRAHTEEPQAKKVRAQ
What is the function of this protein?
Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity.  Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (PubMed:21593607).  Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly (PubMed:24703694).
What are the official names of this protein?
Zinc phosphodiesterase ELAC protein 2, ElaC homolog protein 2, Heredity prostate cancer protein 2, Ribonuclease Z 2, RNase Z 2, tRNA 3 endonuclease 2, tRNase Z 2.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RGLG5_ARATH
Sequence: MGGSSSKESPRGGGSGRRYERSVSGSSSYSSAWDQSSYYQTPNHPSASPVSSYNSGRQTPKNLERKYSRIADNYRSIDEVTAALSHAGLESSNLIVGIDVTKSNEWTGARSFGRKSLHFIGTTPNPYQQAISIIGKTLSVFDEDNLIPCYGFGDATTHDQDVFSFNPNDTYCNGFEEVLMCYREIVPQLRLSGPTSFAPIIERAMTIVEESGGQYHVLLIIADGQVTRSVDTDNGGFSPQEQQTIDAIVRASEYPLSIVLVGVGDGPWDTMRQFDDNIPARAFDNFQFVNFTDIMSKNIDPARKEAEFALSALMEIPSQYKATLELGLLGQRTGHCPDRIALPPPTYATQSMRNSPRTSRSTSFQNKPYDNGVSSTPPSTTHNESQQQFCPVCLVSAKNMAFNCGHQTCAGCGEDLHVCPICRSSISVRIKLY
What is the function of this protein?
Together with RGLG1, mediates the ubiquitination and subsequent proteasomal degradation of the target protein PP2CA.  Functions as positive regulator of abscisic acid (ABA) signaling through ABA-dependent degradation of PP2CA, a major inhibitor of ABA signaling.
What are the official names of this protein?
E3 ubiquitin-protein ligase RGLG5, RING domain ligase 5.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ISPH_ZYMMO
Sequence: MIKIILAQPRGFCAGVIRAIEIVDQALDRVGAPVYVRHEIVHNRHVVDTLKAKGAVFVEELSEVPPGEVTVFSAHGVARTVQKEAEERGLPVVDATCPLVNKVHAQGRRYLSHGRTLILIGHAGHPEIEGTLGQIDGPVHLVGSAEQVDSLDIPSDTPVAFITQTTLSVDDTRSVIAALRKKFTDVIGPDTSDICYATQNRQAAVRDLCKQSDLILVVGSPNSSNSNRLREIGLEEGLPSYLIADGSEIDPVWFEGINTVGLTAGASAPEELVQSVITAIRALGPVTVEQLDGVEEKIAFRLPPTLRHLKARNAAHNNLDNKTAASEEADSLSNDTEQEA
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: PIP_XYLFT
Sequence: MRTLYPEVTPFDHGMLCVDDSHRLYYEQCGNPHGKPVVILHGGPGGGCNDKMRRFHDPDKYRIVLFDQRGAGRSMPHANLTNNTTWDLVADIEKLRVALGITRWQVFGGSWGSTLALAYAQTHPEQTTELVLRGIFMLRRWELEWFYQEGASRLFPDAWDRYIAAIPPVERHDLISAFHRRLTSDDEATRLAAAQAWSLWEGATSCLYMDQDFIASHENPHFALAFARIENHYFVNGGFFEVEDQLLRDAQRIANIPGVIVHGRYDVVCPLQNAWDLHKAWPKASLKITPGAGHSAFEPQNIDALVCATDSFV
What is the function of this protein?
Specifically catalyzes the removal of N-terminal proline residues from peptides.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLO_PSEE4
Sequence: MSDLPDTDFTQRFLFDDRDVRGEMVALERSYAEVLAKHAYPRPVQHLLGELMAAAALLVGTLKFDGLLVLQAQSQGPVPLLAIEYTSEHDIRGLARFEAEQIKDDARLADLMPGGHLVLTIIPVNGQRYQGTVELDGQDLSECFTNYFVMSQQVHTSISLTADGVRARGLLVQQLPAEIHKDIEEREESWAHVKALANTVKAEELLGLDNETVLHRLYHEDAVRLFDIQPLRFRCSCSRERSSNALVSLGEQDAKALVEECGGTVEIDCQFCNERYLFDASDVAQLFAGGGTDVPSETQH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_BARBK
Sequence: MASLKDLRDRIASVKATQKITKAMQMVAAAKLHRAQEAVEAGRSYTQRMDALVTNISKDVDLVDAPLLMRGTGNDHVHLLVVCTAERGLCGAFNTQIARLAREHIQKLHAAGKTVKILTVGKKGADILLRDFKSLMIDHVDLRSVKKIGFAEAAKISKQLIDLFNEGAFDVCTLFYSRFVSVITQRPMALSLIPAGQNPVDEGQDFVDQAKSREVSQSAVYEYEPDVASLLNDLIPRHISVQIFQALLENVAGEMGAKMSAMDNASRNAGEMINKLTVTYNRQRQAQITTELIEIIAGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y384A_MYCGE
Sequence: MGKEIEPIFDLVLLWFLFVPLLIYLFLAFFLFAFTKYIIWELIPFCYSTAFTLIVLFLSGIIPMAWNSWIILLRFFLVLITLMLSFFLLNKMTNFFLIRSKYAIIIAENLLKTGKSKTKNRQKLQQIQSDLERKKSAEIVFKIKKKKPK
What are the official names of this protein?
Uncharacterized protein MG384.1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRP_DANRE
Sequence: MLVVFLCLLSVTLEATEGFKNLSGKVLQFKTATDNSYVKLYPEKPLSLSAFTLCMRVATELPLDREVILFAYYTPDVDELNVWRERDGRVSLYIQSSKDAAFFRLPPLSTLQTHLCVAWESATGLTAFWMDGRRSLHQVYRKGYSIRSGGTVVLGQDPDSYVGSFDVDQSFVGEIANLQMWDYVLSSAQIKAVYYNQDNRVKGNVFDWDTIEYDVTGNVLVATDN
What is the function of this protein?
Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation through its calcium-dependent binding to phosphorylcholine.
What are the official names of this protein?
C-reactive protein, Dare-CRP, Short-chain pentraxin, Dare-PTX.
What is the protein family that this protein belongs to?
Belongs to the pentraxin family.
Protein: PCKG_SULTO
Sequence: MYIMRSSFNFLNLLVSDKMIKKIEILNNSYVEEFIEKTAELCNPSSIYLVTSEEDKEYIRRKAIETKEELPLKTLGHTIHFDHPLDQARARDDTFILTDDKIPFVNTKKREDGIREVLSLLKDSMKGREMYVGFYSLGPKNSIFQHLAIQISDSPYVIHSENILYRLDFDDFKGNKQFLKFVHSKGELDIKKRRIMIDLKEDTVYSVNTTYAGNSVGLKKLALRLTIAKAVKEGWLSEHMAIIGFEGDKGTHYFTASFPSGSGKTSTSMMGKLISDDLAFIREINGVARAVNPEIGVFGIIQGINSKDDPIIWEVLHKPNEVIFSNVLMTEDGYVYWEGSDDKRPERGINYEGFWSNDMNKPASHPNARFTVPLTAFKNLDENYDNPDGVEIEGIIFGVRDYDTLIPVVEAFSCSHGIVTIGASMESARTSAVIGKGDEYEFNPMAILDFMPIHLGEYLGNYLEFCKKLKKVPRIFGFNYFLKEGNRFLNSKEDKRVWIKWAVKRVEGSVDVIYTPIGLVPYYEDLKTLFREMLNKEYTIEDYEKQFTLKLDKYLEKNERILKLYKEILAPKEVIAELEQQKERILKYIDKYGKRISPLDLR
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_NITHX
Sequence: MPRKLPSSPKTSALQLGRAVAWPGSPEEAKLDRVPNPQKGTNYVARFTAPEFTTLCPVTGQPDFAHLVIDYVPGSWLLESKSLKLYLASFRNHGAFHEDCTVAIGKRIATAVRPKWLRIGGYWYPRGGIPIDVFWQTGTVPKGVWIPDQSVPAYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2AG_EMENI
Sequence: MSAQAYYELYRGSSLGLSLTDTLDDLINEGRIEPQLAMKILSTFDRVITEVLADKVRTRLTFKGHLDTYRFCDEVWTFLIKDVNFKLDNQQTISADKVKIVSCNSKRPGEA
What is the function of this protein?
TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.  TFIIA in a complex with tbp mediates transcriptional activity (By similarity).
What are the official names of this protein?
Transcription initiation factor IIA subunit 2, General transcription factor IIA subunit 2, Transcription initiation factor IIA small chain.
What is the protein family that this protein belongs to?
Belongs to the TFIIA subunit 2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL23_SACD2
Sequence: MNLERLYKVLLGPVISEKSAVVADKGNQVVFKVVKTATKPEIKAAVEKLFNVNVRDVRVLNVKGKTKRTRFGLGQRSDWKKAYVRLEQGQEIDFAIAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RLMN_BORPA
Sequence: MESVERVNLLGLDGAALSELVGQWGGKPFRARQLQRWVHQRGADSFDAMTDLARDFRAQLARDCVIEALPVNTEQRSSDGTRKWLFDVGQGNAIETVFIPEDDRGTLCISSQAGCVVNCRFCSTGHQGFNRNLRASEIIGQLWWAKRVLEAAADTARLPGGKAGEDTRVISNVVMMGMGEPLLNYDQVLPALRLMLDDNAYGLSRRRVTVSTSGVVPMMDRLSQDCPLALAVSLHAPNDALRDELVPLNRKYPLNALLAACERYLAHAPRDFITFEYCMLDGINDTDQHARELIQLARQVRCKLNLIPFNPFPASGLKRSPSARVRVFAQRLMDAGIVTTVRKTRGDDIDAACGQLAGEVRDRTRITERNATRTIPIQQVHA
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_HYPMO
Sequence: MGAYKYMQELWRKKQSNVMRFLLRVRCWQYRQLSSLHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQIKFARSLQSVAEERAGRHCGGLRVLNSYWVGEDSTYKFFEVILIDTFHKAIRRNPDTQWITKAVRKHREMRGLTSAGKKSRGLGKGHKFHLTIGGSRRAAWKRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_ACISJ
Sequence: MAQVQGKIVQCIGAVVDVEFPRDRMPKVYDALKLEGSPLTLEVQQQLGDGVVRTIALGSSDGLKRGLMVTNTGNPITVPVGKATLGRIMDVLGNPIDERGPVDQSLTASIHRKAPAYDELSPSQELLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMADSGVVNLENLGESKVAMVYGQMNEPPGNRLRVALTGLTIAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPATTFAHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQVVGEEHYQVARQVQGTLQRYKELRDIIAILGMDELAPEDKLVVARARKIQRFLSQPFHVAEVFTGSPGKYVPLSETIRGFKMIVAGECDHLPEQAFYMVGTIDEAFEKAKKVA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IHFB_MANSM
Sequence: MTKSELIESLVEKNHSISVKSVENAVKEILEHMSQALESGDRIEIRGFGSFSLHFRQPRVGRNPKTGAQVKLDAKCVPHFKAGKELRERVDFNA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: YLR3_EBVP3
Sequence: MDKDRPGLPAPDDNIEEVPSTSGVQERASEGDWENVLIEISDSSSEEEAEDAHLDSSQRGKKRKRVDDDAGGSAPAQHVPPPQLDHPGREAILYRFPLDLRRFIQAIGAAATVSFPMAQVCDVCFCPSHNKVSDLLPLVSAPRHASHRPVFRI
What are the official names of this protein?
Uncharacterized protein BLRF3.