PharMolix/UniProtQA huggingface dataset:
Protein: STK24_RAT
Sequence: MAHSPVQSGLPGMQTLKADPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDEIQIATILREILKGLDYLHSEKKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPHSELHPMKVLFLIPKNNPPTLEGSYSRPLKEFVEACLNKEPSFRPTAKELLKHKFIIRNAKKTSYLTELIDRYKRWKAEQSHEDSSSEDSDVETDSQASGGSDSGDWIFTIREKDPKNLENGTLQPSDLERNKMKDFPKRPFSQCLSTIISPLFAELKEKSQACGGNLGSIEELRGAIYLAEEACPGISDTMVAQLVQRLQRYSLSGGGASAH
What is the function of this protein?
Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation.  Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress.  Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG.  Phosphorylates STK38L on 'Thr-442' and stimulates its kinase activity.  In association with STK26 negatively regulates Golgi reorientation in polarized cell migration upon RHO activation.  Regulates also cellular migration with alteration of PTPN12 activity and PXN phosphorylation: phosphorylates PTPN12 and inhibits its activity and may regulate PXN phosphorylation through PTPN12 (By similarity).  Acts as a key regulator of axon regeneration in the adult optic nerve and radial nerve.
What are the official names of this protein?
Serine/threonine-protein kinase 24, Mammalian STE20-like protein kinase 3, MST-3, MST3b, STE20-like kinase MST3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane. Note=The truncated form (MST3/N) translocates to the nucleus. Colocalizes with STK38L in the membrane (By similarity).
Protein: UREF_ARTS2
Sequence: MAAAGSYQLALQQLTDSALPTGAFAHSLGFETYIERGLVHDEASFGVWLSAFVGQQLSYSDGLAIRFLYEGVSFAELDALLTAQLLPRQLREASTKMGTRLLEIGTEVFPSPELAEYRALVGAGRAAGHQPLAFAVVARSLGVPLTESLAAYLFAAVTSLTQNAVRAIPLGQNAGQRLLRKASDDVAAAVERIGRLAPDDFGAVSPGLEISQMRHERQRARMFMS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MERD_ENTAG
Sequence: MSAYTVSRLALDAGVSVHIVRDYLLRGLLRPVAYTTGGYGLFDDTALQRLRFVRAAFEAGIGLDALARLCRALDAADGDGASAQLAVLRQLVERRREALASLEMQLAAMPTEPAQHAESLP
What are the official names of this protein?
HTH-type transcriptional regulator MerD, Mercuric resistance protein MerD.
Protein: ARGC_SYMTH
Sequence: MTIRVGIAGATGYTGVELVRLLAQHPEAEVVVAGTESYQGQHLAAVYPHLRERVDLVGREASPEALAGCDVVFTSLPHGLTMALAPAVLAAGGRLIDLGADFRLRDVTAYEQWYRKTHTAPDLMEEAVYGLPELYRERIRGARLVGNPGCYPTACALAAAPLLQAGVVETEGIIFDAKSGVSGAGRGVNLGVHFSEVNENFKAYNIAGTHRHTPEIEQTLSDLAGRPVVVSFTPHLVPMTRGILATGYFTLKAERTTEQLVDLFREFYAGEPFVRVRPAGELPTTKQVWGSNYCDIGLQVDPRTRRVLVISVIDNLVKGAAGQAIQNMNLLFGLPETTGLLNAGPVYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_METRJ
Sequence: MPGCLVLVVGPSGAGKDTLLRLARAALAGDPRYVFPRRLVTRPPSADEDNDEIDEAAFAEGCAAGRFTLSWRAHGLGYALPEAVGRRVAEGHVVVCNVSRRVVAGARESGRRVSVVEITAPPEILARRIAARGRAQDGDLAARLAREGGVTADLTILNTGAADEAAARLVAHLRAC
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: Y1314_DEIRA
Sequence: MTQASLIRLSELNNDAQYNLNDTSMYNPVGAAAYGVNGDKIGTVRDALVEPETGRIRYFLVDVGGWFSSKEVLVPVGYGRVDDSGVYFDSLTKDQVKDMSEYRADQAYSSEMMDTDERVLRGNQSQEEYHQRAYQTPDRLQLLEERLVVNKDRFKAGSVQIGKRIETRQETVSVPLQREEVVIERHAVTDGRAVEGAVLGEGHQTMSVDLEAERANISKQAYVTEEVSVGKRAVTETQQVTETVGREVLDVNQTGDVRTTEGTALTDDTTKRNI
What are the official names of this protein?
Uncharacterized protein DR_1314.
Protein: CLK1_MOUSE
Sequence: MRHSKRTYCPDWDERDWDYGTWRSSSSHKRKKRSHSSAREQKRCRYDHSKTTDSYYLESRSINEKAYHSRRYVDEYRNDYMGYEPGHPYGEPGSRYQMHSSKSSGRSGRSSYKSKHRSRHHTSQHHSHGKSHRRKRSRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKVGGRRVAVKIVKNVDRYCEAAQSEIQVLEHLNTTDPHSTFRCVQMLEWFEHRGHICIVFELLGLSTYDFIKENSFLPFRMDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVKSDYTEAYNPKMKRDERTIVNPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSREHLAMMERILGPLPKHMIQKTRKRRYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDAEHELLFDLIGKMLEYDPAKRITLKEALKHPFFYPLKKHT
What is the function of this protein?
Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates.  Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing.  Phosphorylates: SRSF1, SRSF3 and PTPN1.  Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.
What are the official names of this protein?
Dual specificity protein kinase CLK1, CDC-like kinase 1, Protein kinase STY.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RLMM_SHEON
Sequence: MKNLFLFCRAGYEKECAAEIQQRAAELNVGGFVKTNNNDAYVVYQCFEDDGADTLVKQLPLDSLIFARQMFAASELLADLPESDRVSPIVAALSEVSKAGELRVETPDTNEAKELSAFCRKFTVPLRQHLKKSGSLLAQENPKRPIIHVCFIGPGRAYAGYSLSNNSSPNFMGIPRLKMAADAPSRSSLKLDEAFAQFVPKEEQEERVRSGMNAVDLGACPGGWTYQLVRRGMFVSAVDNGPMNEKLMETGQVKHFREDGFRFEPQRKNIYWLVCDMVEKPARVAELIEAWAINGWFKEAIFNLKLPMKSRYKEVMAILNTMQDILKENGITEFKLQCKHLYHDRDEVTVHLWLKPSQPWN
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_HELPJ
Sequence: MLKRIKVGSDLNKKESLLDAFVKTYLQTLEPISSKRLKELANLKVSCATIRNYFQILSKEGMLHQAHSSGARLPTFKAFENYWHKSLRFEVLKVNEKRLKSASENFGLFTLLKKPSLERLERVIECEKRFLILDFLAFSCAVGYSVKMEKFLLELVGRSVKEVRLIAASVNALSLARQLERLEYSSAQITRFNLMGLKTLLNSPLFFDILEGKVLERFKKGLHFIEPDCMLVTRPIEFQNERMQLLCVGKLECDYEGFFQTISKEE
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: NRDI_MYCSJ
Sequence: MGNIVYFSSVSENTHRFVEKLELPATRIPILGRIQDPDFVREPYVLVLPTYGGGHANGPDPDAGGYVPKQVIAFLNNEHNRSLIRGVIAAGNTNFGAEFGYAGDVVSRKCGVPYLYRFELMGTTDDVLAVRAGLENFWKEQTCHPPSQLQSL
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: CTAA_BARHE
Sequence: MAVKSLSNSILTPLQKKNRKQIQVWLYSILLLCLAIVLVGGATRLTGSGLSITEWKPIHGVIPPIGVEQWQEEFLKYQQIAQYKMLNRDMTLSAFKVIFWWEWAHRVLGRLVGLVALLGLIWFWAIKHIEKNVLLQLIIVPILIAFQGVVGWWMVASGIGQSNLTSVSQYRLAFHLITACFVIIFVTYLSQGLAEYSEKPASHRVQYFAGWLVVLILIEVYFGALVAGLHAGKVYNTWPLMDGQFIPDGLLQHDPIWLNLFENPLTVQFVHRFFAYILFFVAIIHAFYVQKNIPHSIHARRAFFICVMIAVQALLGIITLLQEVPISLGLIHQSVALAILCFSVAHWRATKGAYRAIE
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PNO1_PHANO
Sequence: MPAPTALQRRPEEFAENVSEDVSMEASAVPLPEDDADLIDMSIEPGTAIEAAPDALADDMPMTDESGRPKFAPAKSIPLAFRHEQRKVPIPPHRMTPLKTAWPKIYPPLVEHLKLQVRMNIKTKSVELRTSKSTTDTGALQKGEDFVKAFTLGFDVDDAIALLRLDDLYIETFEIKDVKTLQGEHMGRAIGRIAGKDGKTKFAIENASRTRVVLADSKIHILGGFKNIHVAREAIVSLILGQNPSKVYGNLRTVAGRMKERF
What is the function of this protein?
Required for small ribosomal subunit (SSU) synthesis.  Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein PNO1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: SYR_YERE8
Sequence: MNIQALLSDKVSQALIAAGAPAGSEPQVRQSAKAQFGDYQANGVMAIAKKLGMQPRQLAEKVIELLDLDGIASKVEIAGPGFINIFLDRQWVASKVEEALKAPKLGVQPVEPQTIVVDYSAPNVAKQMHVGHLRSTIIGDAAVRTLEFLGHNVIRANHVGDWGTQFGMLIAYLEKMQNENASDMGLSDLELFYQQAKKTYDEDEEFAKRARAYVVKLQSGDEYCRQMWRKLVDITMAQNQIAYDRLNVTLTKDDVMGESLYNTMLPEIVADLKAKGLAVESEGATVVYLDEYKNKDGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLGADRVLYYIDSRQHQHLMQAWTIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRSGGTVKLSDLLDEAIERAGKLIAEKNPDMPADELKQVVEAVGIGAVKYADLSKSRTTDYIFDWDNMLALDGNTAPYMQYAYTRVVSVFKRAGIDESNLTLPLVITEDREAALATRLLQFEEIITTVAREGTPHVMCSYLYDLAGLFSSFYEHCQILNADSEESRQSRLKLAMLTAKTLKQGLDTLGIQTVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_NOCSJ
Sequence: MPRKGPAPKRPIDIDPVYGSQLVSQLVSKVLQDGKKQVAQRIVYTALEGCREKTGTDPVVTLKRALDNVKPAIEVKSRRVGGATYQVPIEVKGTRGTTLALRWLVGYAQDRREKTMHERLMNEILDASNGLGAAVKKREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GCSP_AROAE
Sequence: MPNASPASPLNAPLAELEQRDAFIGRHVGPNATEIATMLAAVGAPDLDTLIDQTVPPAIRLAAPLPLEGPKPEHEALADLRAIAAKNVIRKSLIGMGYYGTHTPAVILRNVMENPGWYTAYTPYQAEIAQGRLEALLNYQQMVIDLTGLELANASLLDEATAAAEAMTMARRVAKSKSNVFYVDEACFPQTIDVLRTRAGLFGFELKFGPAHDAANADAFGALLQYPNERGEIIDLSGTVAALKAKGAVVAIASDLMALVLLKSPGTMGADIALGSAQRFGVPMGFGGPHAAFFATREANVRAMPGRIIGVSKDARGKTALRMTLQTREQHIRREKANSNICTSQVLLANMSGFYAVYHGPQGLRTIAARIHRLAAILAQGLRDAGFNVPAGAFFDTLQVDTGARTAELLAACDAAGFNLRPVSDTVLGLSVDETTTGDDVATLLRLFGASGELAALDAKVGAAGGAIPAALLRDDAILTHPVFNTHHTEHEMLRYLKKLQNRDLALDHSMISLGSCTMKLNATSEMIPITWAEFANLHPFAPREQVRGYLEMIDGLAGYLKAVTGFAAISMQPNSGAQGEYAGLVAIRRYHDSRGDTHRRVCLIPKSAHGTNPASAQMCGMDVVVVACDERGNVDLADLEAKVAQHADRLAALMITYPSTHGVFEESIREICASVHRHGGQVYMDGANLNAQVGLTSPATIGADVSHMNLHKTFCIPHGGGGPGMGPIGLAAHLAPFMADHVVAATGDETRPNKGQGAVSAAPFGSASILPISWMYIAMMGDTGLKLATEVAILNANYVANRLAEHYPVLYTGSQGRVAHECILDIRPIKANTGISEVDIAKRLMDYGFHAPTMSFPVAGTIMIEPTESEDLGELDRFIAAMITIRNEIREVENGAWPTDDNPLKNAPHTQADFIAADGAQWSRPYSREQAVFPLPWVAENKFWPSVNRIDDVYGDRNLFCACVPIEDYAS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RL35_CHLCV
Sequence: MPKMKSNKSVAARFKLTGSGQLKRTRPGKRHKLSKKSSQEKRNLSKQPLVDKGQVGMYKRMMLV
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RM11_DROME
Sequence: MSKAAGKLKSLKKTVERVTHTSKLKTNIPAGMAAAGPPLGPMLGQRAINIAAFCKDFNAKTAEMKEGVPLPCRISVNSDRSYDLAIHHPPATFFLKQAAGIQRGTMTPGKEVAGMITLKHLYEIAAIKIQDPPNVLLTMQQMCEMLISIARTCGIKVVREIDPAAYGEFLEERKLIVEQQRRELQEKREAKMLRTG
What are the official names of this protein?
39S ribosomal protein L11, mitochondrial, L11mt, MRP-L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RHLI_PSEAE
Sequence: MIELLSESLEGLSAAMIAELGRYRHQVFIEKLGWDVVSTSRVRDQEFDQFDHPQTRYIVAMSRQGICGCARLLPTTDAYLLKDVFAYLCSETPPSDPSVWELSRYAASAADDPQLAMKIFWSSLQCAWYLGASSVVAVTTTAMERYFVRNGVILQRLGPPQKVKGETLVAISFPAYQERGLEMLLRYHPEWLQGVPLSMAV
What is the function of this protein?
Required for the synthesis of BHL (N-butanoyl-L-homoserine lactone), and HHL (N-hexanoyl-L-homoserine lactone) autoinducer molecules which bind to RhlR and thus acts in elastase biosynthesis regulation.
What are the official names of this protein?
Acyl-homoserine-lactone synthase, Autoinducer synthesis protein RhlI.
What is the protein family that this protein belongs to?
Belongs to the autoinducer synthase family.
Protein: KDPA_YERPP
Sequence: MVASGFLLIASFMLVLFVLSRPLGGFLARLIEGEPFSALQKVEAGLWRCSGVKNAEMNGWQYALAILCFNLLGIVLLFVLLMTQGSLPLNPEHLPGMSWHLALNTAVSFVTNTNWQAYSGENTLSYLSQMAGLTVQNFLSAATGIAVAFALIRAFARHSATTLGNAWVDLVRITLYVLLPIALIIALIFVSQGVLQNLDDYLHITTLEGVQQTLPMGPVASQEAIKVLGTNGGGFFGANSAHPFENPTAFSNFVQMLAIFLIPCALCFAFGQVVGDNRQGHALIWAMSLIFIVAVVVVMYAELAGNPHLSPLGADSNSNMEGKESRFGILATSLYAVVTTAASCGAVNAMHDSFTALGGMIPLWLMQIGEVVFGGVGSGLYGMLLFVLLTVFIAGLMIGRTPEYLGKKIDVFDMKMTALAILVTPTIVLLGTALALCTEAGRAGILNPGAHGFSEVLYALSSAANNNGSAFAGLSVNTPFYNLLLAAAMFIGRFGVILPVLAIASSLVAKKRQPAGNGTLPTGGLLFIGLLIGTVLLVGALTFIPALALGPVAEHLQVWLAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TSP1L_DANRE
Sequence: MFNRMTSLWMGDLDPYMDENFIKQAFSTMGETAFGVKIITHRVTGGSAGYCFVEMADEASVDRCVQRLNGKLVPGSNPPRKFKLNYATYGKRPEPGPEFSVFVGDLTSEVDDYQLHQFFLKKFPSCKGAKVVTDPYGNSRGYGFVKFSDENEQKKALEEFQNASGLGGKPIRISIAVNKGNKASTYHNQNNTYNTNYQQQYYRQPYNSYYPQWGYDQYSGYNYGYNPYAAPPPMMGPPPPMGMPPMPPDMQGSTEAHDGTEEVEEDPSEDPNPQVDVEELNRQYMERSEELYDSLMECHWLPMDTITSDISMMNGS
What is the function of this protein?
Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins.
What are the official names of this protein?
tRNA selenocysteine 1-associated protein 1-like, tRNA selenocysteine 1-associated protein 1, tRNA selenocysteine-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM TRSPAP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SHE2_YEAS1
Sequence: MSKDKDIKVTPGTCELVEQILALLSRYLSSYIHVLNKFISHLRRVATLRFERTTLIKFVKKLRFYNDCVLSYNASEFINEGKNELDPEADSFDKVILPIASMFVKCVETFDLLNYYLTQSLQKEILSKTLNEDLTLTAESILAIDDTYNHFVKFSQWMIESLRIGSNLLDLEVVQFAIKCADEDGTNIGETDNIFLQEILPVNSEEEFQTLSAAWHSILDGKLSALDEEFDVVATKWHDKFGKLKN
What is the function of this protein?
RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease.  Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell.  Recruits the MYO4-SHE3 complex to the ASH1 mRNA.  Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (By similarity).
What are the official names of this protein?
SWI5-dependent HO expression protein 2.
What is the protein family that this protein belongs to?
Belongs to the SHE2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm and is exported in an mRNA-dependent manner. The presence in the nucleus is essential for PUF6 and LOC1 to bind the ASH1 mRNA.
Protein: TXN1A_PARTR
Sequence: QMDMRCSASVECKQKCLKAIGSIFGKCMNKKCKC
What is the function of this protein?
Toxin that acts as an agonist on melanocortin receptors (MC1R, MC3R, MC5R, MC5R).  After binding to MC1R, the peptide activates the hMC1R/Gs pathway, but after binding to MC4R, it is not able to activate or antagonize the MC4R/Gs pathway.  Inhibits melanocyte stimulating hormone (MSH)-binding to human receptors (Ki=2. 9 uM to MC1R, Ki=3. 9 uM to MC3R, Ki=2. 6 uM to MC4R, Ki=2. 2 uM to MC5R).  This toxin is structurally unrelated to the natural agonists.
What are the official names of this protein?
NU-buthitoxin-Ptr1a, N-BUTX-Ptr1a, NU-BUTX-Ptr1a.
What are the subcellular locations of this protein?
Secreted.
Protein: RS2_METPB
Sequence: MAVDFSMRQLLEAGAHFGHQSHRWNPKMQPYIFGTRNNIHIIDLAQTVPALHAALQAVSDTVARGGRVLFVGTKRQAADAIAEAAKRSAQYYVNSRWLGGMLTNWKTISGSIQRLRKVDETLEGGAVGLTKKERLMLTREKEKLEKALGGIKDMGGVPDLLFVIDTNKEQLAIKEAQRLGIPVAAIVDTNCNPDGISYIVPANDDAGRAIALYCDLIARAAIEGIGRGQGALGIDVGASEEPTAEELPANDDVVASVASDAIAPADVAALAESTEHFEQLAAPRGAPDDLTKLTGVGPQLVQKLNDAGVWHYWQIAAMQADDVAKLDADLKLNGRIARDGWVEQSRAFVEAAAA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: RS6_ECOL6
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: ATPF_ACIFI
Sequence: MNPVGINGTLIVQLVTFVILVALLYKYMYGPLRKVMDDRRAKIADGLAAAERGKEEMALAQKRATELVREAKDKAAEIIANAERRGVELREEAQGKAREEADRIIASARAEIDVETNRAREVLRGQVVELVVNGTQRILHREIDDQTHRDIIDRMVGQL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: G6PI_BRUAB
Sequence: MARDATKLEATVAKLKKHWAESAPRDMRAAFSTDPGRFGRYSLCLDDLLFDWSKCRVNDETMALLKELAVAADVEGRRAAMFAGEHINNTEDRAVLHVALRDTSSKEVLVDGHNVLPDVKHVLDRMAAFADGIRSGALKGATGRKITDIVNIGIGGSDLGPVMATLALAPYHDEPRAHFVSNIDGAHIADTLSPLDPASTLIIVASKTFTTIETMTNAQTARKWVADTLGEAAVGAHFAAVSTALDKVAAFGIPEDRVFGFWDWVGGRYSVWSAIGLPVMIAVGPDNFRKFLAGAHAMDVHFRDAPLEKNLPVMLGLIGYWHRAICGYGSRAIIPYDQRLSRLPAYLQQLDMESNGKSVTLDGKPVSGPTGPVVWGEPGTNGQHAFFQLLHQGTDTIPLEFIVAAKGHEPTLDHQHEMLMANCLAQSEALMKGRTLDEARAQLQAKNLPASQVERIAPHRVFSGNRPSLTLIHDMLDPYALGRLIALYEHRVFVEAQIFGINAFDQWGVELGKELATELLPVVSGKEGASGRDASTQGLVAHLHARRKA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PYRFU
Sequence: MVQKAHSFRRKTRKKLSKHPRRRGLPPLTRFLQEFEVGQRVHIVIEPSYHKGMPDPRFHGRTGTVVGKRGEAYIVEIKDGSKVKTLFIHPVHLRPQK
What are the official names of this protein?
50S ribosomal protein L21e, Large ribosomal subunit protein eL21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: FRMA_SHISS
Sequence: MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEANHEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY
What is the function of this protein?
Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent.
What are the official names of this protein?
S-(hydroxymethyl)glutathione dehydrogenase, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CAUVC
Sequence: MMKITILTVGKLGRMVEAQLALDYASRATASGRALALGPVDILEVEARKPGKAAEAEVLRPHLEGAYVVACDEHGKAWKSRAFADHLARLRDDGNRRVVFLIGGADGLDPSILAAANETMAFGVQTWPHALARAMLAEQIYRAATILSGSPYHRD
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_PYRAB
Sequence: MVSSMKVEWYLDFVDLNYEPGRDELIVEYYFEPNGVSPEEAAGRIASESSIGTWTTLWKLPEMAKRSMAKVFYLEKHGEGYIAKIAYPLTLFEEGSLVQLFSAIAGNVFGMKALKNLRLLDFHPPYEYLRHFKGPQFGVKGIREFMGIKDRPLTATVPKPKMGWSVEEYAEIAYELWSGGIDLLKDDENFTSFPFNRFEERVKKLYRVRDRVEAETGETKEYLINITGPVNVMEKRAELVANEGGQYVMIDIVVAGWSALQYMREVTEDLGLAIHAHRAMHAAFTRNPKHGITMFALAKAARMIGVDQIHTGTAVGKMAGDYEEIKKINDFLLSKWEHIRPVFPVASGGLHPGLMPELIRLFGKDLVIQAGGGVMGHPDGPRAGAKALRDAIDAAIEGLDLEEKAKSSPELKKALDKWGYLKPK
What is the function of this protein?
Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA).  Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type III subfamily.