PharMolix/UniProtQA huggingface dataset:
Protein: NUBP1_NEMVE
Sequence: MADVPKDAPEHCPGTESDKSGKVSACQGCPNQQICASSKPAPPDPDLGKIKERLSSVKHKILVLSGKGGVGKSTFTAHLAHGLAADEDRQVAVLDIDICGPSIPTVFGLQGEQVHQSGSGWSPVYVEDNLGVMSVGFLLAKPTDAVIWRGPKKNGLIKQFLRDVDWGDADFLVVDTPPGTSDEHLSIIQYLNQTEVDGAVVVTTPQEVSLLDVRKEISFCKKVRLPVIGVVENMSVFVCPNCKKESQIFPPTTGGAEKMAVEMKVPFLGRIPLDPRIGRACDEGKSFLSEIPDSPATSSYKDIIEKIVKYCVASQHQS
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor NUBP1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIF1_SCHPO
Sequence: MLLRFFINQPRFIQFTFLRNKKDRILGLQLGKQPFRMSSSSGLKQQGLAQKKKFQLEFDPSSVSKNGTKTEAKVVGTEFGVLLVRARNTYFATAGKCSHYGAPLAKGVVTSDGHIVCPWHGACFNAATGDVEDTPAIAALRTFPVTEEGDGSLWIEVEDKNDNGASVLQPEGCWRNKATEVYNKGSVETEVTAPHVCIIGGGKGASVAAEYLREKNFKGKITIFTREDEVPYDRPKLSKSLLHDISKLALRSKEYYDDLDISFHFNTDVTKIDLAEKKIYCGSDEKPTESYTKLILATGGEPNKLPIPGLDSKNVYLLRSIADASKLAAVTTEAGDKKNIVIIGSSFIGLELAVVLKDHNVSVIGMESIPFEKVMGKEVGTALKALHEQNGIAFYLENSIKEVKTSSNDSSKAEHIVLKDGQSIPADVVILAAGVKPNLRYLGNAVSLEKDGGVKVDEHCRVLGAEDVYAVGDIAHAPFAGLPSSGEKSHTRIEHWDVAGNLGRVAADHILFGNKAGYTTKSFTPYFWSAQGKQLRYCGNNAAEGFDDVVIQGSLSDYKFACFFTKGEKVVGVCSIMKDPVVSQCARLFIKDAMPSKSQLKENFDVLSIPL
What is the function of this protein?
Putative FAD-dependent oxidoreductase involved in the resistance to cercosporin and other singlet oxygen-generating photosensitizers.  Translocates from mitochondria to the nucleus under apoptotic conditions, where it degrades DNA and induces apoptosis (By similarity).
What are the official names of this protein?
Apoptosis-inducing factor 1.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein. Nucleus. Note=Translocates from mitochondrion to the nucleus upon apoptosis induction.
Protein: SLYA_YERPP
Sequence: MESTLGSDLARLVRVWRALIDHRLKPLELTQTHWVTLYNINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISSDEIAVLSGLIDKLEKNIIQLQTK
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: EX7L_BACAH
Sequence: MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFRPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGIGNLHLAYEQLKVRLEEEGLFSQVYKKTIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMEEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_PHOLL
Sequence: MALTKAEMSENLFEKLGISKRDAKDLVELFFEEVRRSLENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVEKATPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MDH_ECOHS
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: AROC_THEP3
Sequence: MRYITAGESHGEALIAVIEGLPSNLLIDEEFINKELKRRQGGYGRGGRMAIEEDKVHVLSGIRNGKTIGSPLTLEIINKDYENWKNKKTPEVTRPRPGHADLAGAIKYNQRDLRNILERSSARETAARVAVGSVAKLLLKELDIYVKSKVLEIGGVKAEEKWRRTIDEAKSKGDTLGGIIEIVIEGVPVGLGSHVQWDRKLDALLAYHVMSVQAIKAVEIGLGFEAARKPGSLVHDEIYYDEERGFYRKTNNAGGIEGGISNGSPIVIKAAMKPIPTLLKPLTSIDINTKEEVKAAYERSDVTAVEAAACVLEAVCAWVIADECLKKFGGDSIEELKKNYDAYLVYVKNF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PCKA_ECO81
Sequence: MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETWQHLKGLVTKQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEELAGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRVSYPIYHIENIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPU_HV1MV
Sequence: MHQENLLALIALSALCLINVLIWLFNLRIYLVQRKQDRREQEILERLRRIKEIRDDSDYESNEEEQQEVMELIHSHGFANPMFEL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: LPXB_SODGM
Sequence: MSARPITIGLVAGETSGDILGAGLIRALRGHLPEARFVGVAGPRMQAEGMEAWYDMEELAVMGIVEVVERLPRLLRIRRDLTRRFTALRPDVFVGIDAPDFTITLEGRLKRRGIRTIHYVSPSVWAWRQKRVFKIGRATDNVLAFLPFEKAFYDCYNVPCQFIGHTLADAMSLDPDKAAARQALGIAAEARCLALLPGSRQSEVAMLSADFLRAAERLYECFPGLEIVVPLVNPARRAQFEHILVAVAPALPVRLLDNQARQAMIAADAALLASGTASLECMLAKCPMVVGYRMKPLTFALARRLVKTPWVSLPNLLAGRELVKELLQEACQPEALAAALEPLLDDDDQRAALLAMFRQLHQQIRCNADEQAARAVLALINR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: NUP_CANAL
Sequence: MKLSTLFTLATTISTLTTFTIASPVVVVEKRAINETALAEDIPTTKNNHAQTSYGKPFAIYQPKAFIISMFSLERDPWLKAMDFVHNITIPGLSPVYPDIHCTTNYTICQITTGEGEINAASSISALTLNPLFDLTKTYFLVGGIAGGEPNYTTIGGVTFAKYAVQVGLEYQLAYEDYHKTNPDWISGYIPYGTDDQNTYPGNVYGTEVFEVNEKLRDRAVELASKVHLNNGTEGNAKFRKLYNETAAQGLPKVVKCDSLTSDNYFTGNVLNDYFANFTLLMTNGSATYCSTAQEDNATLEVMTRLAKHGLVDYDRIMIMRTISDFSRPPPSMSAYEYFFNRSDGGISASLENLVIAGTPIIHDIVQNWDKIYESGEKYSSKNYVGDIFATLGGKPDFGKESFDTA
What is the function of this protein?
Nucleoside permease that transports adenosine and guanosine.  Does not show any transport activities towards cytidine, adenine, guanine, uridine, and uracil.
What are the official names of this protein?
Purine nucleoside permease.
What is the protein family that this protein belongs to?
Belongs to the NUP family.
Protein: ASTA_SHIB3
Sequence: MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAIKTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWHNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSQEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAQGDFPACLVANENYHHFRVVLARTDPATERLILTAAQLDALKCHAGERVRLVRLCAVEKTA
What is the function of this protein?
Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
What are the official names of this protein?
Arginine N-succinyltransferase, AST, AOST.
What is the protein family that this protein belongs to?
Belongs to the arginine N-succinyltransferase family.
Protein: NHAP2_SALCH
Sequence: MDAATIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGIGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLITSGLTGMMAAWLFHLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGSNDPMAVFLTITLIEMIQKHETGLDWMFAVHIIQQFGLGIVFGLGGGYLLQQMINRISLPSGLYPMLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVTPSDLWPIAVPALILSIWMIFFARPLSVFTGLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKRAKVVVPPVGWPVSRVGLDIHPDNPWEQFIYQLSADKWCVGAALRDLHMPNETRIAALFRNNELFHPTGSTRLQEGDVLCVIGRERDLPALGKLFSQSPPVSLDQRFFGDFILEANAKFADVALIYGLEEGTEYRDKQQTLGEIIQQLLGAAPVVGDQVEFGGMIWTVAEKEDNVVRKIGVRVAEDEAE
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GBP5_HUMAN
Sequence: MALEIHMSDPMCLIENFNEQLKVNQEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFSVASTVQSHTKGIWIWCVPHPNWPNHTLVLLDTEGLGDVEKADNKNDIQIFALALLLSSTFVYNTVNKIDQGAIDLLHNVTELTDLLKARNSPDLDRVEDPADSASFFPDLVWTLRDFCLGLEIDGQLVTPDEYLENSLRPKQGSDQRVQNFNLPRLCIQKFFPKKKCFIFDLPAHQKKLAQLETLPDDELEPEFVQQVTEFCSYIFSHSMTKTLPGGIMVNGSRLKNLVLTYVNAISSGDLPCIENAVLALAQRENSAAVQKAIAHYDQQMGQKVQLPMETLQELLDLHRTSEREAIEVFMKNSFKDVDQSFQKELETLLDAKQNDICKRNLEASSDYCSALLKDIFGPLEEAVKQGIYSKPGGHNLFIQKTEELKAKYYREPRKGIQAEEVLQKYLKSKESVSHAILQTDQALTETEKKKKEAQVKAEAEKAEAQRLAAIQRQNEQMMQERERLHQEQVRQMEIAKQNWLAEQQKMQEQQMQEQAAQLSTTFQAQNRSLLSELQHAQRTVNNDDPCVLL
What is the function of this protein?
Antigenic tumor-specific truncated splice form.
What are the official names of this protein?
Guanylate-binding protein 5, GBP-TA antigen, GTP-binding protein 5, GBP-5, Guanine nucleotide-binding protein 5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Lipid- anchor. Cytoplasmic vesicle.
Protein: PUR9_LACCB
Sequence: MKRALLSVSDKTGLVSFAKGLIDRGFELVSTGGTHRELAAAGIAVTSVEEVTGFPEMLDGRVKTLHPKIHAGILARRDDPDHMEALANHDIQPVDLVCVNLYPFAATIKRPDVTRAEAIEQIDIGGPSALRAAAKNSDSVWAVVDPADYEAVLTGLDQDDAHLRQKLAAKVFAITAAYDAQIVHYLDPEPFPEHFTPTYTKRQDLRYGENSHQQAAFYVEPDPNPTSLAAAKQLHGKELSYNNIKDADAALAMLREFSEPAVVAVKHMNPCGIGLGKTIEGAWDKAYAADPMSIFGGIIALNRPVDLATAEKMHKLFLEIIIAPAFDDDAYAVLAKKKNVRLLTINTADTPAELGTETTAIYGGLLIQTRDNQTETPADMTVVTTVKPTDEQLKALAFAQTVVKHVKSNAIVVAQADQTLGIGAGQMNRIGSVELALTQAQQNDNFAGAVMASDAFFPMDDCVDYAAKHDIKAIIQPGGSIRDKDSIEKANQYGIAMVTTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RS4_MALP2
Sequence: MSRYLGSITKKSRRYGFSLLETEREFIKGKKRTYAPGQHGNKRVKLSGYGEQLQEKQKMMYLYGLNDRQFRRTFVIAKHMKGALTLNTFIALESRLDNLVYRMGFAPTRRAARQLVNHGHILLDGKKVTIPSCMVKLEQTIEVAPKSKDLPIVAAGASNTPCKFVDSDLKTKKGKYVRFPERDELPEGINEAYVVEWFNRLV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: OCT2_ARATH
Sequence: MAEPTQPLLTDSNSSSPRSLDDTIESYIGSFGWAQFLQAALVSFSGVFDAQQTFISVFTDSEPTWHCTDSNSICHESISNICILPKTAWSWDYSPHVSVISEWGLQCAGSFVKGLPESSFFVGCLIGGLVLSTLADSSLGRKNMLFLSCLVMAISTMLTVFSPNIWVYAVLRFVNGFGRATIGTCALVLSTELVGKKWRGRVGIMSFFGFMLGFLSLPLMAYMNRGSSWRILYAWTSIPTIIYCVLVRFFVCESPRWLFVRGRREEAISILKRVASIPSTDVSSGGAISMSFSSLPFEEDEEKPSTNVNIFTTMKVLVEKRWALKRLSAVMAIAFGIGLVYYGMPLALSNLDFNIYLSAAFNALMDLPANLITLFLVDKLSRRNALIGFTALGGVSSVLIFALHNMRIGNHGALQLALELISYFSACSAFNMEMIYTIELFPTCVRNSAIAMARQALVLGGVFSPIMVAAGRKNAFWSFGLFGLAIGLLGLFAVGLPETRGSDLCDTMDEEECKDRRSKVAVNNVIA
What is the function of this protein?
High affinity carnitine transporter involved in the active cellular uptake of carnitine.  Also transports organic cations (By similarity).
What are the official names of this protein?
Organic cation/carnitine transporter 2, AtOCT2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: SYC_ALKOO
Sequence: MKLYNTLTRKKEEFIPLEEGKVRMYACGPTVYNYFHIGNARTFMVFDALRRYLIYRGYDVTFVQNFTDVDDKIIRRANEEGVAPEEISERFIKEYFYDAGTLGIEKADIHPKVTENMAEIIAFVAKLVEKGHAYESNGDVYFDVSKYEEYGKLSKQSLEDLQAGARIEINEYKKNPLDFALWKSAKAGEPSWESPWGNGRPGWHIECSAMAKRYLGETIDIHGGGGDLVFPHHENEIAQSEACSGKKFANYWLHVGYLNVDNKKMSKSLNNFFTPREISEEFDLENLRFFMLSAHYRNPINFSRDLLEAAKNGLDRLYTGKNNLEYLLENAAEREVSEEEKNFIHGLQSFKNQFIDAVDDDFNTADGIAVIFDLVREINSHISEKNSKKAVEASYDLLMELTGVLGLLKREAEDLEEEIERLIAERQQARKDKNFALSDKIRDDLKEKGIVLEDTAQGVKWRKL
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_NANEQ
Sequence: MKMKLFGRWDYEDVTVEDPGLRDYINLKPMLIPYSGGRHQKHRFGKAKIPIIERLAGRLMTSGHLGKKHKWTSEHQTGKKYNAYKIIIRTFEIIEKRTKQNPLKVFVKAIENAAPREETTTIEYGGARYPKAVDCSPQRRVDLAIRHMVWGAFHGSRKKPISIEEALAEEIINAYNNSLKSYAIKRKLEIEKTAESAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DCAF1_CAEEL
Sequence: MTSKEIYPLRSTGTMMMISDQDLKLSTQLMLRIAELLLEFDANHEQSSFDPIPILKRISELLEQATDIFIKNDPDPLDDRHPHRTHPDSALGNILKIIFKNDDFMTKLVVSYILARDNVELNIQGSRLLLACIPGLDSKVVFSEPDDFIPRLYTWAGSEGTNETLQGYAMGLLAAALENTENASKYRNENALLVPFGLRRLHELQGRSLEEQKKIGQTDFSQLHAEQSTSNGTSIPSIKITSVDGSTKENEKTFVQSTDPPPPKKRRTEPCLTSLLRTEITQRVPSFHNLRNLDDSNSKWDILQPFLIGDQQVYPLSLATYQRFILQYLAACGEYQDLLLQTFEGNALEILFDYIDLEKSKDVRLTFDALKYLTSLLVHRKFALEFVNKGGIPALLKVPKTSLASVGVVTCLYYIAYSNDVMEILCQMSDEIVDETVQYVLWCLEHSHESGMASACMFFSQGLFYKAILRRFDQYDGPRKLHNYIATLTLMQNNEDVELTEEQIHTSTQCTRGVCTTFRSYLTAHIFIKVENYKKLYGNNLPTGMRFPELVQGDCPDYKSMKPYEEVCWQCEAIVTEMLRFTGSSFREAENLRKLGMVRMFLAVRVLSRDWENISPSLRTEMCVHALETLCMMFCLPSIQTELITQHSYNHSNYDGFTILLQTSLGRYDEDPSLRMAALGCIQRCVYVEPECWKAIIQRVKSSEEKSSSASKRQSKYEIIMNHLERMWTEVRKTDGIMALVNLINCKIPLTEADSIRKTATNTLTGLARHPEVRQILAKLPLIAHNGLQNLMREPVCSDKRDIHAAFCKEAVQLLQVIYGRKIHDQQGKEIQSSEKSHRQWVIENTQVSFNQAELLQLIHDHLLKSKLDSVAAMLKSEAKLPDRPASRSINTPILNKPLPSSGNNFSKINDTYPTLAPRTLESEIGGISARRPSNAASLSSPAMATRSHSTDDDVFATPTLPRRYTTSGAFPKKLMISPARQKLRPLTPGESSSGYRPIKDLNSIVTDYFRNQHSTCKNPVTTCPPFSLFYQHKCPELSYQTNVVRNISLRTLDQELLRPHERVYSQWTNERTIFSRFRNWKTIHDHDESYTKATFSVDDEHLIVGLFNGEVHWINVDTGLDEGHTNCHGSALTNIEPSKDGSMMLTSSAFSRPLSALWRLGEALQRVHTYREDSCVKFANTTMQRIVGTCRDKATVYDTETNHVLDTYLSGIDGLQYEKNYASFSPDDKLIFNDGLLWDVRKKNSAIHVFDRLSKITLFGTFHPHGTQIVINSEVYDIRTFRMLHHVPELNRCQVSFNSTGNIMYATEVTDVHCPDYDEKIFSSFRTFETRDYSALTTFEGRRPVIDLCASHQDQKMCVIEKVRPQMSDYMIQASTQLKIVEIGRLKDNEDENDEEEDEQREDHDEDEDSDESGDGDDDEEIGGNSSDRESVFRTLGRLGDESDSGSSVDDNDTLDDLDFENAQNRIIRRQAQRRRQRLNSSENDAELPGSDEGSDEDGDDDEDGEGDPDFDMGAAIDDLVDAVDEEVDEDELGTDGDDDDSGSWRTTNSIDSEDINLDDLDEEEARVVENEGNNERPARPVDPIEAAAAARRAILGRGLRDLRMGIRGGNRRRNGGGLEQAEMLNARAEEQRVSFMEALVRGAEAERREEEGGDDGESSSSSSSDTDEYQSEEEEINSVSTTALNPALRRRNRRPDDEA
What is the function of this protein?
Component of the cul4-rbx1-ddb1-dcaf1 E3 ubiquitin-protein ligase complex, dcaf1 may function as the substrate recognition module within this complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor homolog 1.
What is the protein family that this protein belongs to?
Belongs to the VPRBP/DCAF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_BURCM
Sequence: MIGRIAGILLEKNPPHLLVDCNGVGYEIDVPMSTFYNLPQTGERVVLLTQQIVREDAHLLYGFLTPQERTTFRELLKITGIGARMALAVLSGMSVQELAQAVTMQDAARLTRLPGIGKKTAERLLLELKGKLGADLGALAGAASQSDHAADILNALVALGYSEKEGLAAIKNVPAGTGVSEGIKLALKALSKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: Z_BPPHM
Sequence: MGQLGKIQRSTRQPIGLNGLFDPNNHSTRWWLRKHVHLRSLRNSDTSCKSRDKCSTFQSLQSYL
What are the official names of this protein?
Uncharacterized protein Z.
Protein: SRP54_CANLF
Sequence: MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLRENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:6938958, PubMed:6413076).  As part of the SRP complex, associates with the SRP receptor (SR) component SRPRA to target secretory proteins to the endoplasmic reticulum membrane (By similarity).  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes (By similarity).  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA (By similarity).  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit SRPRA (By similarity).  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (By similarity).  Requires the presence of SRP9/SRP14 and/or SRP19 to stably interact with RNA (PubMed:6413076).  Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP54, Signal recognition particle 54 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
Protein: RL21_METAC
Sequence: MTNSHGEKRCTRYKLQKTVRERGISPVSRAIQEFEEGQMVHIDIDPSVQKGMPNPKFQGSTGKVIGQRGRSYVLEVRSGNAMKEVFSLPQHLKPQKY
What are the official names of this protein?
50S ribosomal protein L21e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
Protein: VF226_ASFP4
Sequence: MKMETFLVCLFHNADGLHQQIQEILYLLRMHIYETNLYLKQELSRLIYPNRQLSFVLLMPLSLLRNWDDIEYLTDVVDDKQTLHYAANLLTNYVLHLSMFQKLTKPYFLLAVKRVSEKLNKKQRHSFYEVLVTSETLNNYENLSKNILNTLMFAVRYVFKPTPNYSEILAELEKKNKIHHIIFNMVITDFAQIREQQMDKHLCETNNELRQECKETIFDLKVVGNV
What is the function of this protein?
Plays a role in the inhibition of host NF-kappa-B and IRF3 signaling pathways.  Mechanistically, promotes the degradation of host IKBKG through enhancing its ubiquitination leading to inhibition of both pathways.
What are the official names of this protein?
Late protein I226R, pI226R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I226R family.
Protein: SARR_STAA8
Sequence: MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRSESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANIQKLISELEEYIKN
What is the function of this protein?
Negative regulator of sarA transcription at late exponential and stationary growth phases.  It contributes to the modulation of target genes downstream of the sarA regulatory cascade.  Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus.
What are the official names of this protein?
HTH-type transcriptional regulator SarR, Staphylococcal accessory regulator R.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.