PharMolix/UniProtQA huggingface dataset:
Protein: END4_CHLTB
Sequence: MFILPPPQEPLLGAHTSAAGGLHNALYEGRDIGATTVQLFTANQRQWKRRALTQEMVDQFRIALNETSLSYIMSHAGYLNNPGAPNPEILEKTRVCMHQEIADCISLGISFVNFHPGAALSDSKESCLDRAITSFSQMAPLFENHPPLVVLLETTAGQGSLIGSSFEELAYLIQGIKALIPIGVCLDTCHIFAAGYDISSVAGWEQVLKHFDAVIGLSFLRAIHLNDSVFALGKNKDRHAPIGEGCIGSDSFCFLMQDERTRMLPKYLETPGGPDLWTKEIRYLQKVC
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SYRA_RHIME
Sequence: MSFRFVCLILWLLLCASSLAIYFALQPCPGFIVTTLACLLLFQLAYFGSVLLLVCLAAIAQLSARLRIFGIFSENRNHSSK
What is the function of this protein?
Increases exopolysaccharide abundance.
What are the official names of this protein?
Protein SyrA.
Protein: SYR_OENOB
Sequence: MNFTHIIAEKINQTLENTFDLDKLEKLVEKPKDLNRGDYAFPTFSLSAKFHEAPQKIALKIADEIDRTNFANVKAVGPYVNFFIQRVEFTNQLLKEILLNDDFGRNNQGAGKKIVIDMSSPNIAKPMSMGHLRSTVIGEAISKIAKANGYQTIKINFLGDWGTQFGLMIAAYKLWGDDKLINKNPVDELVKLYVKINKESETDKSLKDSGRAWFKKLEDGDPEAVKLWNWFKSVSLKEFQEVYDRLGVSFDSMNGEAFYNDKMEPVVKMLASKGLLTESQGAEIVDLPNLLPKDNYPIAMIKRSDGATQYITRDLASAIYRHDAYDFAKSLYVVGAEQKDHFDQMKAILKLAGDDWADDIEHIGFGMITMNGKKMSTRKGNIVPLVDVLDTARQLAAEQISEKNPGLENADHVAEEVGAGAVVFNDLQKDRNLSIDFNLEKIVQFEGDTGPYVQYTHARAMSILRKSGQQAILNTGVTFVDEEAWPIVSRLSAYPEMIKRAWQLREPSIVAKYLLSLARDFNSYYAHTKILVNNEKMQSRLSLVQGVCSVLKSGLNLLGVSAPNQM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_SHESR
Sequence: MSTNPKPAFRRILLKLSGEALMGDEGFGIDPKVLDRMAQEVKELVELGIQVGVVIGGGNLFRGEGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLKGVCDDYNWAEAISLLKSGRVVIFAAGTGNPFCTTDSAACLRGIEIEAEVVLKGTKVDGVYSDDPMKNPEAVKYDELSYTEVLDKELKVMDLAAFTMARDHDMPILVFNMNKPGALRRVVMGEEEGTMIRAK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_CUPPJ
Sequence: MSDILDKILAVKADEVSAARKKRDLPSLRAEAESLRNEAGFAPRGFERSLRDKIAAGHAGVIAEVKKASPSKGVLRENFVPEAIAESYASHGAACLSVLTDVNFFQGHADYLKRARGACPLPALRKDFMVDLYQVYEARSWGADCILLIVAALDPGLMADLEACAHELGMDVLVEVHGADELDSALRLKTPLLGVNNRNLRTFEVSLDNTLDLLPSMPADRLVVTESGILGPNDVKRMRDADVHAFLVGEAFMRAKDPGVELARLFA
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: TPS5_RICCO
Sequence: MATEGLLSAETDQDVARFLANFPPTEWGYSFASLLPQDSEFESHTKELDLVKEKVKDMLMQSRKELTENIEFVNCLCRLGVSYHFESEIIEQLSHIFISLPKILEENDYSLYILTLLFRVLRQHGYKMPCDVFNKFKDSNGEFKKCMTADVRGLLSLYEATFLSVHGEDILDEALAFTRQHLETLAEKSSPHLARHIRNALHLPFHHAPERLEILQYICFYEGEKSMNETLLKFAKLDFNRLQLLYRKELGLLSRWWKDINLTEKLPYTRDRIVEAYAWAAGIIIDPQFSRARLQFAKHLILISVMDDTYDSYGTFDELKHFTAALQRFTFEPTIELPEYMKFLYNILWNFFQETEKDETQGCACKTSFAREMLKELARSYFAEAEWYNDGVLPTFDEFMQFGLVSSTFDYHASAFFLGVEDLGMKEFIWLRDNPTIAKTAKLFGRLFNDIAIREDEQKKGDYPSAIKCYMNDHDVSLEKAKEDILKMLEDGWKDMNEELMKPTTVPKILTKFSINFVRMSDFTYRGGIDKYTCGTELKEFVKKLTIFPLQI
What is the function of this protein?
Catalyzes the cyclization of farnesyl diphosphate to multiple sesquiterpenes, such as olefins and sesquiterpene alcohols.
What are the official names of this protein?
Terpene synthase 5, RcSeTPS5.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: HLDD_BURM1
Sequence: MTLIVTGAAGFIGANIVKALNERGETRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGAQFLYASSAAIYGGSTRFVEERSVEAPLNVYGYSKFLFDQVVRRVLPNAKSQIAGFRYFNVYGPRETHKGRMASVAFHNFNQFRAEGKVKLFGEYNGYAAGEQTRDFVSVEDVAKVNLFFFDHPEKSGIFNLGTGRAQPFNDIASTVVNTLRALDNLPPLTLAQQVEQGLIEYVPFPDALRGKYQCFTQADQTKLRAAGYDAPFLTVQEGVDRYVRWLSGQV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: SFSA_THESQ
Sequence: MRLILPADTEGIFLERKSRFTGVALVEGKKTLIHIHNTGRLPLLKKGKRVLLKRAESDRRKTGWDLLAVEHRDEFVFVHSGFHSIVAGKILEELFPGSTIESEKRFENSRFDFLIDRRTFVEVKGCTYEEDGVAMFPDAPTERGRRHIEELISSVKSGFKALLLILVFLESDCFLPNRSVDPAFSRVFWRALKSGVNIDVFRVKYDGEYLCSTEKLSICEEV
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: RPIA_BURVG
Sequence: MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSVATTERLKSHGIKVFDLNEIDALQVYVDGADEIDASGAMIKGGGGALTREKIVASVADTFVCIADGSKRVPVLGAFPLPIEVVPMARTAIGRRVAALGGVPVLRVTKDGAPYITDNGNEIIDVKGLQIAEPRAFEAKVNAWPGVVTVGLFAERGANLCLLGTENGVETIIYPA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: MICU1_CAEBR
Sequence: MLRHNFRSSIFIRIVANSWSITRSVSSAPIKAESRKQQDSLKNIDSGEAYTALGNIRQKKDVFHYTDRASGTGYSHYSNSVYQHRPYIWPPLRKMYNWNYAFVIAGMVILMSDFEWIKEQIKGASTPFRPEASQKEESTDSGTEIEVKEKPKKKKLGFRERRIIEYEDRLRLYSTPDKIFRYFATLKIIDPNDESGRIFEVFMTPEDFLRSFTPGVMQPRRWGLDSFKAYNPEKHKRHKFSDPNSIFYKLGENGLINFSDYLFLMTLLSTSHADFALAFKIFDVDGNGALDKEEFTKVQQLIMSQTTVGQRHRDHVTPNSSFRVETNSALETYFFGKDGKGSLSSEKFIEFQERLQHDILKMEFERRDAMENSDGLITEESFAQLLLLHAQIAEKKQKHMLKRVKRRFKGDQSKGVSFDETKAFFEFLYHIDDVDIALHFHKMAGMSIDAKLLKRVAVKVTGIPLSDHVVDVVITLFDDNLDGKLSHEEMVAVMRRRMRRGLERPRDTGLFRLFDAVLECGKRAYHASPLPFY
What is the function of this protein?
Key regulator of mitochondrial calcium uniporter (MCU).
What are the official names of this protein?
Calcium uptake protein 1 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MICU1 family. MICU1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein. Mitochondrion intermembrane space. Note=The topology is subject to debate.
Protein: GLYA_STRA5
Sequence: MIFDKDNFKEFDQELWQAIHDEEIRQQNNIELIASENVVSKAVMAAQGSVLTNKYAEGYPSHRYYGGTDCVDVVESLAIERAKTLFNAEFANVQPHSGSQANAAAYMALIEPGDTVLGMDLAAGGHLTHGASVSFSGKTYHFVSYSVDPKTEMLDYDNILKIAQETQPKLIVAGASAYSRIIDFEKFRQIADAVDAYLMVDMAHIAGLVASGHHPSPIPYAHVTTTTTHKTLRGPRGGLILTNDEAIAKKINSAVFPGLQGGPLEHVIAAKAVALKEALDPSFKIYGEDIIKNAQAMAKVFKEDDDFHLISDGTDNHLFLVDVTKVIENGKKAQNVLEEVNITLNKNSIPFERLSPFKTSGIRIGTPAITSRGMGVEESRRIAELMIKALKNHENQDVLTEVRQEIKSLTDAFPLYEN
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_BACC4
Sequence: MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPSVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDENDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGVRVESLAEIASLDNGTVTFVQQETAEVK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_STAA1
Sequence: MSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEWDQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEFDLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYRQRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTHHNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYHDIMDLTESMVRHIANEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFYEVKSDEEAKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPLAKKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDEDYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_RUEPO
Sequence: MFAVLKTGGKQYKVQAGDVLRVEKLAADAGEKVQFNDVLMLGGDAPVVGAPLVDGAAVQAEVIDQIKGEKLIHFVKRRRKHSSQRTKGHRQKLTLVRITEILTSGADKTGVKAATGQAAAGAAAPAAAAPAAAGSDDLTKITGVGPAAAKKLVEAGIGSFAALAALSDEQIAAIDAVKVKPEWVEQAKELAQG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: IF1_MESH2
Sequence: MANLPKEQKLLFQGKVTHVFNAQEYEVTLENGIKLNCHIAGKMKIHHIKIIIGDMVKVEISPYDLSKGRIVYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_BACCN
Sequence: MENVYENSYMIVGIFLLLGILLPVVALTLGKLLRPHKPSEAKNTTYESGIEPYHDANVRFHARYYIFALLFVIFDVETLFLYPWAVAYDKLGLFALIEMLIFVAMLLIGLAYAWKKKVLQWL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL7_CARHZ
Sequence: MSKVQEILEAVKSLTVLELAELVKAFEEEFGVSAAAPVAVAAAPAAGAAAAAPAQEEKTEFDVILVSPGAQKVNVIKVVREITGLGLKESKDLVDGAPKPVKEKVSKADAEAIKAKLEEVGATVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: VG50_BPMD2
Sequence: MTEGEIPWGPTGELVYNRTYSRVKPDGTRETWPETVERVVSGNLALVDSRYQLPGEREDLLRLMREFKILPAGRHLWASGVKNAQHLFNCWVSGWTEKPSDHFEFTFMRLMEGGGVGANYSNRFLADYPHVKQELEVHIVCDEDHDDYADLAEAGQLSSRYDSDWVDAFVIEDSREGWAAALVDLIDTHYRDDVAHKERVYDVSRVRAAGRKLKTFGGTASGPVPLAKMLTEVSEILSRCAREGEQYRFEDGGALTGLDAMEIDHAIAQCVVAGGVRRSARMAMMHWADWQVETFTNIKQDSGSHWTTNISVEVDDAFWSLAKAPVDPLNPRSTKAHRVLKALSEGAVRNGEPGMWDSSLSNVGEPNEVVCTNPCGEITLEPWEPCNLGHINLAAFVTDAGKTDYIDLIRAHRLMTRFLIRATFSAVADPKSREVLDRNRRIGVGHLGVASYLALTGRRYSQAPGDKRFTAFLREMAAEVDRAAEEFSHELRIPVPVKKRTVAPTGTIAKMPGVSEGIHPIFSRYFIRRIRFSVLDNDQFLTASQYAADGYHVEKDQYDKSGNTWVVEIPTKDTLVEAVAARFGRDAEDIVESANELTLHQLLAFQALYQTCWADNAVSFTANVDPDAYEGVDVAADLQRFSGLIKGSTIFPEESFPQAPYERITKQQYEAAAIKAVADGVDEECANGACPIK
What are the official names of this protein?
Putative adenosylcobalamin-dependent ribonucleoside-triphosphate reductase, Gp50.
What is the protein family that this protein belongs to?
Belongs to the class II ribonucleoside-triphosphate reductase family.
Protein: PPR3C_CLABA
Sequence: MPVDMAVQLYITSSPPLHHRFLSSYKDYRVRNLISVNCKPLRPCINTKNTHNTSLNPPCSVWKAPEPKAKKKVVFADSKGMSLTAVRVFSPCENKKSDSQVQFQLPKLEVALKPVQSRILAFRQPATEYMEFRKRLMKNSVCLESCTLQGHTLTGTIKVRNVSFEKSVQVRITFDSWENHRDIECTFLNDVCGCRDTDTFSFIIEIPACVLPQDSVEFCVSYTCGGKTHWDNNNGKNYALVTTHDEKKDKTKETDLLDPFRNQQKRNRFTADWNSLMIGIRGPTW
What is the function of this protein?
Acts as a glycogen-targeting subunit for PP1 and regulates its activity.  Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 3C.
Protein: SYM_COXB1
Sequence: MTTEKRQILVTAALPYANGPIHLGHMVEHIQADIWVRFQRLKGNDCLFICGEDAHGTAIMITAQKQGLPPEALVAKMHKEHARDLGGFLIEYDNFYTTHSPENRELAELIYTRLKDKGDIFAKTISQAYDPVKEIFLPDRFIRGTCPRCGAKDQYGDVCEVCGATYSPTELIDPVSALSGAKPIEKNSEHFFFSLNRYTQLLKKWIDAGHLQPQVANKLKEWFSEDLKPWDISRDAPYFGFEIPHAANKYFYVWLDAPIGYMASLKNLSKQRPSVNFDAYWKEGSQTELYHFVGKDIVYFHALFWPAMLSSAGFRLPTAIYVHGYLTVNGQKMSKSRGTFITAHHYLDHLSPEYLRYYYAAKLSAQVEDIDLNLDDFIQRVNADLIGKYVNLASRCAGFITKNFGGKLANELPEPDLYESFLQTEQTITDYYESLNYSKAVRVIMSLADRANQYIDAKKPWALAKEINQEAQVQAVCTQGLNLFKILTTYLKPILPVTAKKVEQFLNCDELNFANLKTPLLDHSVNPFEPLMQRLLPETAAQLTHE
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_RHORT
Sequence: MAEIIDIHAREILDSRGNPTVEVDVLLDSGAFGRAAVPSGASTGAHEAVELRDGDKTRYAGKGVLKAVEAVNGELFSALSGLDATDQLLIDQAMIDLDGTPNKARLGANAILGVSLACAKAAAEEAELPLYRYIGGARSHILPVPMMNIINGGQHADNPIDVQEFMIMPVSAPTVADAVRMGAEVFHALKKKLKDAGHNTNVGDEGGFAPNLASADEALAFIVKAIEAAGYKAGEDIVLALDAASSEFYKDGKYVLAGEGKTLDAEGMVKYYAELCKRYPILSIEDGCAEDDWAGWSLLTAELGAKVQLVGDDLFVTNPLRLAEGIRKGVANSILVKVNQIGTLSETLEAVEMAHKAGYTSVLSHRSGETEDSTIADIAVATNCGQIKTGSLSRSDRLAKYNQLIRIEEELGPVAVYAGASILRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: KAD2_CAEBR
Sequence: MDKKSDFGQIFLVPKTQPAAQPAVTPSTGPSETLARGIRAIFIGPPGSGKGTQAPAFASKYFSCHLATGDLLRAEVASGSEFGKQLKATMDAGKLVSDDVVCKLIEQKLEKPECKYGFILDGFPRTSGQAEKLDEILERRKTPLDTVVEFNIADDLLVRRITGRLFHIASGRSYHLEFKPPKVPMKDDLTGEPLIRRSDDNEETLRKRLVQYHQMTVPLVDYYQKHGVHVKVDAAKPMADVKAHIDSVFAKFTQKKV
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.  Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
What are the official names of this protein?
Adenylate kinase, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate kinase cytosolic and mitochondrial, Adenylate monophosphate kinase, Lethal protein 754.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion intermembrane space. Note=Predominantly mitochondrial.
Protein: SSUB_CUPNH
Sequence: MQMYPVEQAALVELEAGLARREAAQPAAEAPRKAGGVALHVRQVVKRYDGREVLHNVALDVAPGEFLAIVGRSGCGKSTLLRLVAGLEAADGGSITVDGESAAKGRARHADVRVMFQDARLLPWKRVLDNVALGLPRTRRGEAADVLAQVGLADRAREWPARLSGGQRQRVALARALVHHPQLLLLDEPLGALDALTRIEMQGLIESLWRRLGFTALLVTHDVSEAVALADRIVLIEDGRIAMDERVALARPRERGAAGFAQLEAAVLKRVMRQAPQAQVPSHAGAHADPAATTAPLNVSWAA
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLA8_ANOGA
Sequence: MPSWWCCCCLVVLLYAQRMIVPSSAQNDGSDELQECPGGFCSPKYLCPNGTYNEANAQNQEIIMLRFGEEDVCQDYMQVCCSNATSMRYELVTNNEPVEYGCGISNPGGLIYQVEGNRTYAQYGEFPWVVAILEAFYSSNEQQFTYVGGGTLIHPRFVVTAAHIFNKTENLVASFGEWDMNRDENVYPKQNIDIDRTIIVHPEYNSVGLLNDIALAQLKQNVVYDKHIRPICLPNPTDRFDDQLCISTGWGIEALTSAYANVLKRVDLPVIARASCKKLFAETRLGPFFRLHKSVLCAGGEEGADMCDGDGGSGLACPNESGAYVLAGIVSWGLSCHQQNVPGAYVNVARFVTWINATIEGIL
What is the function of this protein?
Inactive serine protease which plays an essential role in the innate immune response against bacteria, fungi and protozoa infection by activating the melanization cascade (PubMed:16922859, PubMed:17537726, PubMed:23166497, PubMed:33045027).  In the melanization cascade, acts downstream of TEP1 and SPCLIP1 to promote CLIPA28 and CLIPC9 proteolytic cleavage and CLIPC9 recruitment to microbial surfaces (PubMed:33045027).  In the resistant strain L3-5, required for the melanization of killed parasite P. berghei ookinetes which results in their clearance (PubMed:16922859).  In the susceptible strain G3, appears to be dispensable for ookinete elimination which occurs by lysis (PubMed:16922859, PubMed:33045027).  Required for the melanization of Gram-positive and Gram-negative bacteria (PubMed:17537726).  During the late stage of fungus B. bassiana-mediated infection, required for the initiation of hyphae melanization by promoting prophenoloxidase PPO activation (PubMed:23166497).
What are the official names of this protein?
Inactive CLIP domain-containing serine protease A8.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. CLIP subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the hemolymph.
Protein: URE21_BRUSU
Sequence: MIPGEIITLEGDIELNQGQPTVTMRVANTGDRPIQVGSHFHFYEVNAALSFDREKARGQRLDIAAGTAVRFEPGQERDVTLVPIRGHREIYGFRQMIMGKL
What is the function of this protein?
Disrupting the ure1 operon causes loss of urease activity, decreased resistance to low pH killing in vitro and decreased pathogen survival when inoculated in BALB/c mice by gavage.
What are the official names of this protein?
Urease subunit beta 1, Urea amidohydrolase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_ENT38
Sequence: MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVSFDVVSRYLRFLGYTLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDSEPRATHHIHEIIEITEKLIERGHAYVASNGDVMFSVPTDPGYGQLSRQDLEQLQAGARVDVVDVKRNPMDFVLWKTSKEGEPSWPSPWGEGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHGGEYVNYWMHSGMVMVDREKMSKSLDNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARSALERLYIAVRGTDKSVAPAGGEAFEARFIDVMNDDFNTPEAYSVLFDMAREINRLKVEDVSAANALASHLRKLAAVLGLLEQDPETFLQSGAQNDGDEVAKIEALITARLEARQAKDWAAADAARNRLTEMGIVLEDGPQGTIWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_OPITP
Sequence: MPRLLGVEIPAKKKVAYSLRYINGIGPTRADLLVKEAGLSPDMRAQDLTEEQLNKILHLITEHKWVLEGDLRREIAGNLKRLQAINCYRGVRHRRGLPVRGQRTSTNARTRKGPRKTVGVSKAAAAAKA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.