PharMolix/UniProtQA huggingface dataset:
Protein: TERJ_ASPTN
Sequence: MSRNDVIDDEVHGVHGEYDDSSTLTGSHEDLDVKRPQSLSGEIAFIVVVCMAQLVSQAGLGQVISILPVLGDSFGIGNNMSQLSWFPAAYSLTVGTFILGAGRLGDLYGHKLLFTAGYFWLAIWTLVAAFAESSGPVFFCCCRVLQGIGPAFLLPNGMAILARSYEPGTRKEMVFSAFGSTAPSGFIFGGLVSALAAKYQSWPWGFWFMAILEAVCGIAAIFWVPRTPTPRRETTHSLWARMDIAGCVTGISGLLLFNVALNMAPGARWQDPYIYILLIASLVFFGLFGYIERKAVFPLIPFSAITPDISFVLATLACGWAAFGVWVFYGWEFVQNFRGISPLFACLQFSPAAISGFVASFTTGLILQKLPASVVMMISAAAFCTADTLYATMPIAQSYWAQLFVSIIVMPWGMEMSFPASNILLSNAMPQEHQGVSASLVATIMNYAISLGLGFGAIVETDLNKNGTDLLRGYRGAWYLGVGLAASGIILTMFFALHEYRKSVPMKNKAASREEYLA
What is the function of this protein?
Efflux pump that might be required for efficient secretion of terrein or other secondary metabolies produced by the terrein genne cluster (PubMed:24816227).
What are the official names of this protein?
Efflux pump terJ, Terrein biosynthesis cluster protein terJ.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DHK2_STRVN
Sequence: MATDAPEAPVALVTGSSSGIGQTVAQRLAAEGYRVVVNSARSVEDGEKTAAALPDALYVRADVSEEADARRLVDTAVEHYGRLDVLVNNAGRTRAIPHADLAAATPEVWREILGLNVIGTWQTTVAAMPHLARSGNGSVVNVSSIAGSRPAGSSIPYAVSNGGHRAQTRLLANTVGPAVRVNAVAPGLIETPWTQNSDFFAPIAEHVRQTTPLRRTGRPEDVAEAVLGLVRATYTTGQVLLVDGGAHLL
What are the official names of this protein?
Granaticin polyketide synthase putative ketoacyl reductase 2, ORF6.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SYP_METB6
Sequence: METDTGALPKKQDFSEWYNEILWRAEIMDVRYPVKGLYVWFPYGFAIRKFVYQHLRELLDRDHKETLFPLLIPEQEFMKEAEHIKGFEDEVYWVTHGGTTPLEVKLALRPTSETAIYPMFALWVRSHADLPIKIYQIVNTFRYETKQTRPLIRLREITSFMESHTVHATWDEAEIQVESEIALTREFYRNLCIPIIISKRPDWDKFPGADYTIAVDAIMPNGKTLQIGTVHHLGNHFSRTFNIQYEDKNGEQKEAYQTCYGISERCIAALISLHGDDKGLILPPTVATFQVVIVPITIGKRHEDVLAAAGKLKNDLENAGLRVTLDTRDLRPGAKYYWWEIRGVPLRLELGPRDLDSGKAMAVTRTGEKTTICLANAAEDTTSILTGITDAIRAKAGEHTKSHLCTTHTMDGLDIALNEGKVAVVHWCRDRTCGDTIEEKANSSLLGTEVRSEYIEATDGPCIICGKPGKATLVGRTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1767_PECCP
Sequence: MDKDTKPCFQDVLEFVRMFRRKNKLQREIVDNEKKIRDNQKRVLLLDNLSEYLKPGMSIEDVQNIIANMRGDYEDRVDDYIIKNADLSKERRELSKKLKAMGEVK
What are the official names of this protein?
UPF0265 protein PC1_1767.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: OGT_THESM
Sequence: MISIKSFQIGEKEIVIAILFDKKIQGITFSFDGEQFLQERVNALVEHLTNRGVKVNLEERDSELPALVYKILIGEIRNQDGLEYLSFEGTTPFEKKVYETLTKKVKRGEVITYGELAKMLRSSPRAIGGAMKRNPYPIIVPCHRVIASNNIGNYTPKREYKRFLLETEGVKTWTS
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_HALVD
Sequence: MGIMSKILGGGGSRTTEDYVELDLDDFDTARGDAGLSVHIAEIGGQQDVIAIKDAVYDGNLVIADITRHTTSDSTMEHIIDDLRQVAREVDGDIVQKGDDQIVITPTGISISRQKLNG
What is the function of this protein?
Involved in cell division.  Probably acts as a membrane anchor for FstZ2, tethering its filaments to the division site.  May be involved in septum closure.
What are the official names of this protein?
Cell division protein SepF.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes in a ring-like structure at the cell division plane at midcell. Localizes at the future site of cell division straight after the closure of the septum. Co-localizes with FtsZ1 and FtsZ2. FtsZ1 is important for its proper localization.
Protein: UPPP_STRP6
Sequence: MLIIELLKAIFFGIIEGITEWLPVSSTGHLILVQEFIRLNQDKAFIEMFNIVIQLGAIIAVMLIYFERLNPFQPGKTAREVQLTWQLWLKVVIACIPSILIAVPLDNWFEAHFYFMVPIAIALIVYGIAFIWIEKRNAQQEPAVTELARMSYKTAFFIGCFQVLSIVPGTSRSGATILGAIILGTSRTVAADFTFFLAIPTMFGYSGLKAVKFLLDGHHLDFAQVLILLVASLTAFVVSLLAIRFLTDYVKKHDFTIFGKYRIVLGSLLLIYSFFKFVF
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUEA_HELPJ
Sequence: MKEFDLESYDYHLPKELIANYPVLPKEKAKLLVYERRSQTITHTTFEHVLDFFPKNALVVLNDTKVIKARLFGSKHAFLPSKTTEVFFHRFFKGNTALTQIKGKIKVGDKIFFDANYYAEVLELLHNGQRLIAFYDNQTPLNQENILKLLEQYGHMPLPPYIKRADESLDAHEYQSVFAKHIGAVAAPTASLHFSQNALEKLLKDFKHAFLTLHVGAGTFLSVETKDIREHQIHTEVLHIPKKSQEILQESQEVLCIGTTALRSVEYFKRLKNPNQESFECDIFLHLANPIQHVNHLLTNFHLPKSSLLMLVSAMIGLEKTKEIYKIAIEKKYRFYSYGDGMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSF_ARATH
Sequence: MSLSRRDPLVVGSVVGDVLDPFTRLVSLKVTYGHREVTNGLDLRPSQVLNKPIVEIGGDDFRNFYTLVMVDPDVPSPSNPHQREYLHWLVTDIPATTGNAFGNEVVCYESPRPPSGIHRIVLVLFRQLGRQTVYAPGWRQQFNTREFAEIYNLGLPVAASYFNCQRENGCGGRRT
What is the function of this protein?
May form complexes with phosphorylated ligands by interfering with kinases and their effectors.
What are the official names of this protein?
Protein TWIN SISTER of FT, TFL1-like protein.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OXLD1_BOVIN
Sequence: MLLRRVTGGGRAVVAATLGGGPLSSWDWCQKLPGGGSLLRRIQVREAHREFGKNHVEVGSQAGAAGTGQPKSSLQGGGPSGPLYPPPPELQPPTNCCMSGCPNCVWVEYADALLQHYQDGGERALAALEEHVTDENLKAFLRMEIQLRIRSGG
What are the official names of this protein?
Oxidoreductase-like domain-containing protein 1.
Protein: 3SI14_DENAN
Sequence: LTCVKSNSIWFITSENCPAGQNLCFKRWQYISPRMYDFTR
What is the function of this protein?
Binds irreversibly and specifically to M1 (CHRM1) muscarinic acetylcholine receptors, blocking further binding of antagonists and preventing the action of agonists.
What are the official names of this protein?
Muscarinic m1-toxin4.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Aminergic toxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MURD_STRP8
Sequence: MKVISNFQNKKILILGLAKSGEAAAKLLTKLGALVTVNDSKPFDQNPAAQALLEEGIKVICGSHPVELLDENFEYMVKNPGIPYDNPMVKRALAKEIPILTEVELAYFVSEAPIIGITGSNGKTTTTTMIADVLNAGGQSALLSGNIGYPASKVVQKAIAGDTLVMELSSFQLVGVNAFRPHIAVITNLMPTHLDYHGSFEDYVAAKWMIQAQMTESDYLILNANQEISATLAKTTKATVIPFSTQKVVDGAYLNDGILYFKEQAIIAATDLGVPGSHNIENALATIAVAKLSGIADDIIAQCLSHFGGVKHRLQRVGQIKDITFYNDSKSTNILATQKALSGFDNSRLILIAGGLDRGNEFDDLVPDLLGLKQMIILGESAERMKRAANKAEVSYLEARNVAEATELAFKLAQTGDTILLSPANASWDMYPNFEVRGDEFLATFDCLRGDA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_BURM1
Sequence: MQILLAALIAYLIGSVSFAVIVSAAMGLADPRSYGSKNPGATNVLRSGNKKAAILTLIGDAFKGWIAVWLARRYGLPDVAIAWVAIAVFIGHLYPVFFRFQGGKGVATAAGVLLAVHPVLGLATALTWLIIAFFFRYSSLAALVAAVFAPLFDVFLFGTNHNPIAWAVLAMSVLLVWRHRGNIAKLLAGEESRIGDKKKAAANGNAQDGGKA
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPA_BART1
Sequence: MLKGAITALITPFDHKGAIDERAFCDFVEWQITQGINGVSPVGTTGESATLSHEEHKQIIELCVEQVAKRVPVVAGAGSNSTSEAIELAQHAEKAGADAVLVVTPYYNRPNQSGLYKHFSSIAKAVSIPIIIYNIPGRSVIDMAVETMRDLYQNFNNIIGVKDATSRIERVSEQGEKCGKDFVQLSGDDCTALGFNAHGGVGCISVSSNVAPKLCAELQAACFHGDYKTARELNDRLMPLNRAVFIEPSPAGIKYAAAKLGLCGETVRSPIVPLTESTKKIIDEALSHAGLLKA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOA2_SCHPO
Sequence: MEFPIDDEELLDERNKLLQICNMDEQTMFYKWESWCLQRGNTPKLDLDTFKAFAKDMKFQMERQVKATLKQNPERKSIKQIPGMNIDSILGLPVKTTASGDSLMQESKPSTETFELNSSDAGRVLEVLNKELKIVTSKPSAPSKLVIVANFDLKAFNYRIMYQKLYDSSEVLDDRIELFSALTCRKYNISDEDLANPSELTQEPVVVVGRIVVESTNLGGRLNQNSILLESSRRLGAGVRVRLKVDDLPSYSIFPGQIVSVKGSNPSGNMFIAKEILPIPPLPFPSSSKQEHATFVANTNNQPISIYIASGPWSLRDDLSFSPLKSMISYVNKNPVDLVILCGPFLDINHILIRTGNITGTSATSLEELFKERVTPILSQLTCPCILIPHINDAASDHPAWPQDAFNRVALGLPSNFKCFPNPCMFSINDVVFGVSTNDILLHTSREELFRLPSHGNLFARLVSHVLHQRHFYPLFPGGSLEKCNPSNLDIAHLKLGEFLNTMPDILILPSDLRYFVKNVENVVSLNPGKATKGINLGTFAKLTIAPLELGDNGSSNHYSHRVWLRTKAEILKL
What is the function of this protein?
Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis (PubMed:15314153).  During the S phase of the cell cycle, the DNA polymerase alpha complex (composed of a catalytic subunit pol1, an accessory subunit spb70/pol12 and two primase subunits, the catalytic subunit spp1/pri1 and the regulatory subunit spp2/pri2) is recruited to DNA at the replicative forks (By similarity).  The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands (By similarity).
What are the official names of this protein?
DNA polymerase alpha subunit B.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase alpha subunit B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Present both in soluble and chromatin-bound form.
Protein: GNB1L_MOUSE
Sequence: MAALFPPPPGPRFVLRGTQSAVNTLHFCPPSQAAGNPLLFSGSQNGLVHIWSLQTRRIVTTLNGHGGQGVIWLKTLPQGHQLLSQGRDLRLCLWDLEEGRNTIMDSVQLDSVGFCRGSILVRGQQCWMLAVPGKGSDEVQILEMPSKTSVCTLKPEADARPGMPMCLGLWQTNSSLRPLLLAGYEDGSVTLWDISERKVCSQITCHEEPVMGLDFDSQKAKGISGSAGKVLAVWSLDDQQSLQVKKTHELTNPGIAEVTIRPDHKILATAGWDHRIRVFHWRTMKPLAVLAFHSAPVYCVAFAADGLLAAGSKDQRISIWSLYPCP
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein 1, G protein subunit beta-like protein 1, WD repeat-containing protein 14, WD40 repeat-containing protein deleted in VCFS, WDVCF.
Protein: MGSA_SINFN
Sequence: MADRKCLALIAHDQKKNDLAAFAKAHEATLSGWKIVATGTTGGRVLDACPGLDVTRLKSGPLGGDQQIGALIATGDVDCLIFFVDPLTAMPHDVDVKALMRLAIVYDIPMALNRATAEQLIDFRRT
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: ORC3_MOUSE
Sequence: MHTGPRTMATSSVSKGCFVFKPDFKKRKVFVPIEDYFNNEELDSEDSKLRFETYSLLWQRMKSETEQLQEELNENLFDNLVDFLQKSHPEFQKNSRDWGSQMKFREIPTAALILGVNVTDHDVILRSLTETLQNNVTPYVVSLQAKDCPDVKHFLQKFTSQLMDCCVDRHSKEVTSGKALKKTNYSMDSLCSWYSAVTQKADHKVTIKKRTASGHWRSPPVVLILKSMESFTSKVLQDFITISSQHLHEFPLILIFGIATSPVIIHRLLPHSVSSLLCVELFQSLSCEQHLTVVLDKLLLTPQFPFKLSKKALQVLTNIFLYHDFSIQSFIKGIKLSLLEHFYSQPLSVLCCDLSEAKKRVNVFSVSQCENIRRLPSFRRYVENQPLGKQVALLTNETFLKEKTQSLLEDLHVYHINYFLVLRCLHNFTSSLPKYPLGRQIRELYCTCLEKKIWDSEEYKSALQLLRMLAKDELVSILQRCIEVLDSSTEKQLGNTTQKIKDFLTQFQNLDADSKEEEDACGSQPKGLQKTDLYHLQKSLLEMKELRRTKKPTKFEMLRENVMNFIDNLVRDYLLPPESQPLHEVVYFSAANTLREHLNAAPRIALHTALNNPYYYLKNEELEGCIPNTAPDICIAYKLHLECSLLINLVDWAEAFATVVTAAEKMDANSTVSEEMSEVIHARFIRAVSELELLGFIKPTKQKTDHVARLTWGGC
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.  Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.
What are the official names of this protein?
Origin recognition complex subunit 3, Origin recognition complex subunit Latheo.
What is the protein family that this protein belongs to?
Belongs to the ORC3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: Y923_METJA
Sequence: MEIFKLLRKDRKMLFLMFIGTVSFLFIFIPFLKFQMIGSSHKINAYPSLSAVCGLLLGPIYGFFAVMLVTLIYFFLNPKAFYFGIYSLIPPTLAVISAGALSEGKWKYSAIILIVGLLLFYLTDVGRVAFYYPYLSTLALLLILIFREKISKLLFSKDWKKMIVGATILSFSSVMTDHLYGSILGIVYLHLPAEDYISVIPLFIKERLIMTVIGAFFVIFAIEISKCFLKNATKLKEKLLKSYIDKEIKINCKNMLNVDEELLKKYNVKIPSEEEQKEILKTLVEVVVFNNDKDENR
What are the official names of this protein?
Uncharacterized protein MJ0923.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL16_SHEPW
Sequence: MLQPKRMKFRKMFKGRNRGLANGTEVSFGEFGLKAVGRGRLTARQIESARRAMTRHIKRQGQIWIRVFPDKPITSKPLEVRMGKGKGNVEYWVCQIQPGKVLYEMNGVSEELAREAFALAAAKLPLKTTFVTKTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SYAC_CAEEL
Sequence: MKHLTASEVRSTFINFFREKKEHTYVHSSSVIPHDDPTLLFANAGMNQFKPLFLGIADPNSDLAKLKRAVNTQKCIRAGGKHNDLDDVGKDVYHHTYFEMLGNWSFGDYFKKEIITWAWELLTTVYGIPAERLYVSVFGGDEANGVPADSEARDIWRSVGVPDERILNFGMKDNFWEMGDVGPCGPCSEIHYDRIGNRDASHLVNADDPMVVEIWNLVFIQFNREEGGVLKPLPAKHIDCGLGLERLIAVMQDKTSNYDTDIFQPIFEAIHKGSGVRAYTGFIGDEDKDGVDMAYRVVADHVRTLTIALSDGGRPDNSGRGYVLRRILRRGVRYASEKLNAQPGFFASLVPVVISILGETFPELSRDPVTVMDIINDEEKQFLKTLSRGRVLFQRAVQSLPEGTMTFPGDVSWRLYDTYGFPADLTQLMAEEKGLSVDNTAFEEARRKAIETSSAGTGKFRDTLDLDVHALAELQQKGVPTTDDSPKYAYTFTGEGSDAVYKFEPCVGKILAIRRDGKFVDQLAAGEEGAILLDRTNFYAEQGGQIYDVGVLTKVNDESNEFNVSNCQVRGGYIVLVGSAEGSFSVGDQVNERFDEDRKQLIMKNHTGTHVLNYALRKVLADSDQKGSLVAPDRMRFDFTNKAGMTVQQVKKAEEYAQQLIDTKGQVYAKNSPLGEAKKVKGLRAMFDETYPDPVRVVAVGTPVEQLLQNPDAEEGQNTTVEFCGGTHLQNVSHIGRIVIASEEAIAKGIRRIVALTGPEAERAIARADRLTARLEEESKHADKKDELLANKDKFKALQKKIQEIVDEANGAQLPYWRKDSIREKAKAIQKTLDGYTKAQQAAVAEKVLGEAKELAAVAEQPTVLVHVFAANANSKAIDNALKLLKDTKAVMAFSVNEDSGKVLCLAKVDKSLVSNGLKANEWVNEVCTVLGGKGGGKDANAQLTGENVDKLDAAVELAQKFALAAIN
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, cytoplasmic, AlaRS A, Alanyl-tRNA synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: R15PI_THEKO
Sequence: MAVVKEVLEIAEKIKNMEIRGAGKIARSAAYALQLQAEKSKATNVDEFWKEMKQAAKILFETRPTAVSLPNALRYVMHRGKIAYSSGADLEQLRFVIINAAKEFIHNSEKALERIGEFGAKRIEDGDVIMTHCHSKAAISVMKTAWEQGKDIKVIVTETRPKWQGKITAKELASYGIPVIYVVDSAARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTAKEHRVWTMIAAETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKNIEVWNPAFDVTPPEYVDVIITERGIIPPYAAIDILREEFGWALKYTEPWED
What is the function of this protein?
Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO.  Only accepts the alpha-anomer of D-ribose 1,5-bisphosphate as substrate, being inactive on the beta-anomer.  Displays a strict substrate specificity, since other phosphorylated sugars such as R5P, ribose, G16P, G6P, G1P, FBP, F6P, and PRPP, are not substrates.  Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO.
What are the official names of this protein?
Ribose 1,5-bisphosphate isomerase, R15P isomerase, R15Pi, Ribulose 1,5-bisphosphate synthase, RuBP synthase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. R15P isomerase subfamily.
Protein: RL4_ECOLC
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: ENV_HV1EL
Sequence: MRARGIERNCQNWWKWGIMLLGILMTCSAADNLWVTVYYGVPVWKEATTTLFCASDAKSYETEAHNIWATHACVPTDPNPQEIALENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCSDELRNNGTMGNNVTTEEKGMKNCSFNVTTVLKDKKQQVYALFYRLDIVPIDNDSSTNSTNYRLINCNTSAITQACPKVSFEPIPIHYCAPAGFAILKCRDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVIIRSENLTNNAKNIIAHLNESVKITCARPYQNTRQRTPIGLGQSLYTTRSRSIIGQAHCNISRAQWSKTLQQVARKLGTLLNKTIIKFKPSSGGDPEITTHSFNCGGEFFYCNTSGLFNSTWNISAWNNITESNNSTNTNITLQCRIKQIIKMVAGRKAIYAPPIERNILCSSNITGLLLTRDGGINNSTNETFRPGGGDMRDNWRSELYKYKVVQIEPLGVAPTRAKRRVVEREKRAIGLGAMFLGFLGAAGSTMGARSVTLTVQARQLMSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSGKHICTTNVPWNSSWSNRSLNEIWQNMTWMEWEREIDNYTGLIYSLIEESQTQQEKNEKELLELDKWASLWNWFSITQWLWYIKIFIMIIGGLIGLRIVFAVLSLVNRVRQGYSPLSFQTLLPAPRGPDRPEGTEEEGGERGRDRSVRLLNGFSALIWDDLRSLCLFSYHRLRDLILIAVRIVELLGRRGWDILKYLWNLLQYWSQELRNSASSLFDAIAIAVAEGTDRVIEIIQRACRAVLNIPRRIRQGLERSLL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: PSB1_ARATH
Sequence: MTKQHANWSPYDNNGGTCVAIAGSDYCVIAADTRMSTGYSILSRDYSKIHKLADRAVLSSSGFQADVKALQKVLKSRHLIYQHQHNKQMSCPAMAQLLSNTLYFKRFFPYYAFNVLGGLDEEGKGCVFTYDAVGSYERVGYGAQGSGSTLIMPFLDNQLKSPSPLLLPKQDSNTPLSEAEAVDLVKTVFASATERDIYTGDKLEIMILKADGIKTELMDLRKD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-1, 20S proteasome beta subunit F-1, Proteasome component 5, Proteasome subunit beta type-6, TAS-F22/FAFP98, TAS-G39.20.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.