PharMolix/UniProtQA huggingface dataset:
Protein: RLMN_JANMA
Sequence: MTTLTNLLDLDPAQLIAYCGELGEKPFRAKQLQRWIHQFGASDFDAMTDLAKSLRDKLATRAIIAAPAVISDHTSADGTRKWLVDVGQGNAVETVFIPEENRGTLCISTQAGCAVNCRFCSTGKQGFNRNLSVGEVIGQLWMAEFELRRTKGIEPGPKGERQITNVVMMGMGEPLLNYEPTVTALKLMLDDNAYGLSRRRVTLSTSGVVPMIDKLSQDCAVALAVSLHASNDALRDGLVPLNKKYPLVELMAACKRYLEFAPRDFVTFEYCMLDGVNDSDQHARELIALVRQADVPCKFNLIPFNPFPESGLTRSHNPRIKAFAQVLMDAGIVTTVRKTRGDDIDAACGQLAGEVQDRTRVQDRMKKMAEYQEKFGKNFGRIVEISS
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_BURP0
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARPVNFHPDAEAAS
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RL1_STRTD
Sequence: MAKKSKQMRAALEKIDSTKAYSVEEAVALAQETNFAKFDATVEVSYNLNIDVKKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDELVDKINGGWLDFDVVVATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGNVQAIIGKVSFEAEKLVENFKAFNDAIQKAKPATAKGVYITNLSITTTQGPGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: AGAP4_HUMAN
Sequence: MGNILTCRVHPSVSLEFDQQQGSVCPSESEIYEAGAGDRMAGAPMAAAVQPAEVTVEVGEDLHMHHVRDREMPEALEFNPSANPEASTIFQRNSQTDVVEIRRSNCTNHVSTVRFSQQYSLCSTIFLDDSTAIQHYLTMTIISVTLEIPHHITQRDADRSLSIPDEQLHSFAVSTVHIMKKRNGGGSLNNYSSSIPSTPSTSQEDPQFSVPPTANTPTPVCKRSMRWSNLFTSEKGSDPDKERKAPENHADTIGSGRAIPIKQGMLLKRSGKWLKTWKKKYVTLCSNGVLTYYSSLGDYMKNIHKKEIDLQTSTIKVPGKWPSLATSACTPISTSKSNGLSKDMDTGLGDSICFSPSISSTTSPKLNPPPSPHANKKKHLKKKSTNNFMIVSATGQTWHFEATTYEERDAWVQAIQSQILASLQSCESSKSKSQLTSQSKAMALQSIQNMRGNAHCVDCETQNPKWASLNLGVLMCIECSGIHRSLGTRLSRVRSLELDDWPVELRKVMSSIGNDLANSIWEGSSQGQTKPSEKSTREEKERWIRSKYEEKLFLAPLPCTELSLGQQLLRATADEDLQTAILLLAHGSREEVNETCGEGDGCTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALTYARQASSQECINVLLQYGCPDKCV
What is the function of this protein?
Putative GTPase-activating protein.
What are the official names of this protein?
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4, AGAP-4, Centaurin-gamma-like family member 1, Centaurin-gamma-like family member 5.
What is the protein family that this protein belongs to?
Belongs to the centaurin gamma-like family.
Protein: DNAG_THEPD
Sequence: MGGLPVSPKYVIKAKMEIKGSVEKHDIIGAIFGQAEGLLGSELDLRELQKTGRVGRIEVNTRSQDGTLVAEIEIPTNLDMAETAIIAATIESIDKVGPYPAKTEVVSIEDVRAEKRQKIIERAVELYKKLLESVPESRELVEEVLRRVRVAEIVEYGEEKLPGGPEVETSDTVILVEGRADVQNLLRHGYKNVIALGGATIPKSIKSLVENKKVILFVDGDRGGELIARNVINALKVDFVARAPPGREVEDLTAKEIARALQNKIPVDEFLQALEREKKQQKEVKAEIVVPPAKLIKSATKKNPEIAQEIVVPAEVYEKLEELKGTLEAVIYDENWQVVEKVPVRDLVNRLKEVERAAHVVLDGIITQRLVDVAYTKGLKSLIGVRIGEIIRKPDNIVLATFSSVKKSEENIQESVSTGESAQTSP
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: RM52_DROME
Sequence: MLKITKICLASSATSTAQRSIALTAPRAIDQKWRAAKGLPENPNAFGPLTNLPDYTYLDGRPTPLGANQKRRLIKQQEIATRIVELSGELEFAKQRHERLKANAESEKQRLIRSKLKPKGHFLLKK
What are the official names of this protein?
39S ribosomal protein L52, mitochondrial, L52mt, MRP-L52.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL52 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: KCY_PSESM
Sequence: MKIKAPVITIDGPSGSGKGTVAGLLAKKLGWCLLDSGALYRLLAFAARNHGVDLTNEEALKLLAAHLDVQFETTAAGQGQRIILEGEDVTQAIRNEQIGSGASQVASLPAVRDALLMRQRAFQEEPGLVADGRDMGTVVFPDAPLKVFLTASAEERARRRYLQLKAKGDDVSLSSLLDEICARDERDTQRAVAPLKPAHDAIQLDSTELSIEQVLERILSEIALRDIAG
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XIAP_XENTR
Sequence: MEPQLAEFVLKEEMTCQCPKMSDGAYDMDVDQNYFEEEVRLASFANFPSSYPVSAPALARAGFYYTGDGDRVKCFSCLAMVEGWQHGDTAIGKHRKISPNCKFINGFNNLRSDCILTQVPVMQNGFQNSAEDLAERSSSEIMADYLLRTGRVVDMSTPKYPRHMEMCSEEARLQTFQNWPAYSPLTPKELANAGLFYTGINDQVKCFCCGGKLMNWEPSDKAWTEHKKHFPECYFVLGRDVGNVATEANTHGGRRRGSELACPAMNDYNARLETFSSWSFPIDKETLAKAGFYSIGDGDATKCFHCGGVLNCWSATDDPWEEHAKAYPGCKFLIDEKGQHFINHAQLKRPILHKANSADASPALPKDSNLLKSPLVTDAQQMGFPLEEIKKVMGQKLKTTGKNYTCVEEFVSDLCAQKETVLEKPKEIEISLEEKLRQLEEEKICKVCMDRRISIVFIPCGHLVACAVCADVLDKCPICCTIVERRQKIFMS
What is the function of this protein?
Multi-functional protein which regulates not only caspases and apoptosis, but also acts as an E3 ubiquitin-protein ligase mediating ubiquitination and subsequent proteasomal degradation of its target proteins.  Acts as a direct caspase inhibitor.  A key apoptotic suppressor in eggs.  Acts as a positive regulator of Wnt signaling.
What are the official names of this protein?
E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 4, RING-type E3 ubiquitin transferase XIAP, X-linked inhibitor of apoptosis protein, X-linked IAP.
What is the protein family that this protein belongs to?
Belongs to the IAP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYG_THUAL
Sequence: MADFDAVLKCWGPVEADYTTMGGLVLTRLFKEHPETQKLFPKFAGIAQADIAGNAAISAHGATVLKKLGELLKAKGSHAAILKPLANSHATKHKIPINNFKLISEVLVKVMHEKAGLDAGGQTALRNVMGIIIADLEANYKELGFSG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ATPF_OPITP
Sequence: MLPLFLAAAEAHVAEPGLVAELVEKFGLDPKYILIQTFSFLIVLGILYRFAIKPTIAAMEERAEKVGAGLKYAEEMQAKLAAAQQESAAIVKKSQVEASRIVDEARRTAKDYLDKQTQEAAAKASETIAKAQQAIELEHRKMLADARTEIARLVVITTERVLAQKLSDSDRAAYNASATRELTNV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYB_MICMJ
Sequence: MTIIRKKHPLIKLINHSFIDLPTPSNISSWWNFGSLLGLCLIVQILTGLFLAMHYTSDTATAFSSVAHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGVYYGSYNMIETWNMGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPTGLNSDADKIPFHPYYTIKDFLGVLILLMAFMILTLFFPDILGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILSIMPLLHTSKQRALTFRPITQTMYWILVADLLILTWIGGQPVEYPFIIIGQTASIAYFAIIVIFMPIAGMIENNILDLD
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS3_ELUMP
Sequence: MGHKINPKGLRLGYTQDWQSRWFAPKNMPALIIEDKRIRELIEERFKMAAISFVGIERAGAFLRINIHTARPGVVIGKKGADIEQLRKDLEKMTGSKTFVNVVEIKNPETDASLVAQSICMQIEKRAHYGAAMKKAIEKALAGKALGIKIMVSGRLGGAEIARTEWKREGRVPLHTLCAEIDYGTAEAMTISGKIGCKVWIFKKTHFAKSPKEILHELRKHREVTETPSGSAETVTEAK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ANHX_HUMAN
Sequence: MQSFLTLLKEHEDTCAPPAELVTLAGRLCRDFQDDLAQLQPLVTAILDSQLRLHLLDNADVALACARVLDQQEQQQAACRLLEGCQVPGGSQELVQLWNDIHYRLVMRRLGVAALTPVQKFRCRKRNPPPPSLCPEGLKSRNFPREVREKLHNFAVGVNTNPSKAERENLALETSLTPEQVYNWFANYRRRQRALPQHMKPAQQATAEDPGARERGPDLLQPSGNPRVDSGFVDRPQWSEEREEKGPPQSPQTTQGPWEPLALAPDFPADETVSKPLDVSGHPQSVQLEEGLGTSSGRTELRVGSFLVTQPPLQAPEFILTQSPPELAPAPSAFPGPVSAMELSQALPSSQVQCSDSQASGDAFWGARMLLEFSGSSLG
What are the official names of this protein?
Anomalous homeobox protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROL_ENT38
Sequence: MTQPIFLVGPRGCGKTTVGLELARACQSQFVDTDHWLQTKAGRTIAEIVEKEGWETFRALETETLKAVSAPSTVIATGGGIILAEHNRGFMREHGIVIYLCAPVATLVERLEAFPEEGQRPTLTGKPISDEVSEVLAERDALYREAAHHVVDASQTPEQVVSHIVTALRLACAS
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPS_PICTO
Sequence: MSDIGNFVSRIYESKLLEEIKKHPVPGHLGIITDGNRRYARSIGISENEGHVKGKEKLEEVLNWSMEVGIHMVTVYAFSTENFKRKSDEVNFLFNLINDAFIDLLNDERVYKNGIRVKVIGDISKLPDYLKETIKRVEGETNKFKNFRFNLAIGYGGRQEIIDAIKKIGQDILNGKIKVDNINEEMFRSYLYDKTLPDPDLILRTSGEERISNFLLWQSAYSELYFADVNWPELRKIDFLRAIYSYQNRKRRFGE
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP).  It is probably the precursor of glycosyl carrier lipids.
What are the official names of this protein?
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific), Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: COX3_EMEND
Sequence: MIYQSKRNFQNHPFHLVSPSPWPLFTSISLFILTTATVLFMHGFEGFQYLVPVAVINVMYVMGLWFRDVISEGTYLGNHTNAVQKGLNLGVGLFIISEVFFFLAIFWAFFHSAISPSVELGAQWPPLGIQGINPFELPLLNTIILLSSGVTITYAHHSLIQGNRKGALYGTVVTILLAIVFTFFQGVEYTVSSFTISDSVYGSCFYFGTGFHGLHVIIGTAFLAVGLWRLAAYHLTDHHHLGYESGILYWHFVDVVWLFLYISVYYWGY
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SUCC_ACIB3
Sequence: MNLHEYQAKALLKEYGMPVQEGILATNADEAVAAFEQLGGKFAVMKAQVHAGGRGKAGGVKVAKSKEDVIEFANNIIGTRLVTYQTDANGQPVNSIIVAEDVYPVERELYLGAVVDRSSRRITFMASTEGGVEIEKVAEETPEKIIKVEVDPLVGLQPFQAREVAFALGLKDKQIGQFVKIMTAAYQAFVENDFALFEINPLSVRENGEILCVDAKVGIDSNALYRLPKVAALRDKSQENERELKASEFDLNYVALEGNIGCMVNGAGLAMATMDIIKLYGGQPANFLDVGGGATKERVIEAFKIILADTSVQGVLINIFGGIVRCDMIAEAIIAAVQEVNVTVPVVVRLEGNNAELGAKLLDESGLKLISANGLSDAAEKVVAAVKA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: BPIFC_MOUSE
Sequence: MRTKQVPVLWACFLLWSLYIASSQTVYPGITARITQRALDYGLQVGMKVLEQLAKEIVIPDLNGSESLKFLKIDYVKYNFSNIKINAFSFPNTSLAFVPGVGIRALSNHGTANISTNWSVKAPLFRDSGAANLFLSGIYFTGIVAFTRNDFGYPALELQDCHVQVSHARVSFFGSLSALYNSFAEPMEKPILKNLNEMVQLCPIAISQVEQFNVNISALEVLTKIDNYTVLDCSLISPPEITENHLDFNLKGAFYPLESLVDPPFTPAPFHLPESRDSMLYIGISEYFFKSASFAHYVSGALGTTLSTREISNYFSQNVQGFGSVLSKIAEIYVLSQPFILQMMATGPPMVNLQRNNFSLEFPAAVIMLTQLDNSTIQPIVSMDFVASTSVGLAILGQKLICSLSLNRFRLSLPENSQRDAKVVRFENILSSILHFGVLPLANTKLQQGFPLPNPYNISFINSDIEVLEGYLLVSSDLAYDTSSKPQPNLNSWGDLNLVHRPWREQPTH
What are the official names of this protein?
BPI fold-containing family C protein, Bactericidal/permeability-increasing protein-like 2.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: CALCR_CAVPO
Sequence: MRFTFTRQFLAFFILISNPASILPRSENLTFPTFEPEPYLYSVGRKKLVDAQYRCYDRMQQLPPYEGEGPYCNRTWDGWMCWDDTPAGVLSVQLCPDYFPDFDPTEKVTKYCDESGVWFKHPENNRTWSNYTLCNAFTPEKLQNAYVLYYLAIVGHSMSIITLVVSLGIFVYFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRKDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVSVFNEAKHLRWYYLLGWGFPLVPTTIHAITRALYFNDNCWISVDTHLLYIIHGPVMVALVVNFFFLLNIVRVLVTKMRETHEAESYMYLKAVKATMILVPLLGIQFVVFPWRPSNKVLGKIYDYFMHSLIHFQGFFVATIYCFCNNEVQTTLKRQWAQFKIQWNQRWGTRPSNRSAAARAAAAAAEAGGDNIPVYICHQEPRNDPPNNQGEEGAEMIVLNIIEKESSA
What is the function of this protein?
This is a receptor for calcitonin.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.  The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.
What are the official names of this protein?
Calcitonin receptor, CT-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_CLOBL
Sequence: MLEIEKPKIECVENAEDGSYGKFVIEPLERGYGITLGNALRRILLSSLPGVAADHIKIDSVLHEFSTVQGVKEDVTELILNIKCLALTMNGEGPKTIYIDEVGPKEVTAADIKTDGDVEVINKDLHIATLDENGKMYMEINVNRGRGYVTQNKNKTKDMPIGSIAVDSIYTPVKRVNFSVENTRVGQITDYDKLTIEVWTNGTIRPEEAVSLSAKILIEHFKLFMTLTDHADDMEIMVEKEEDKKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELCERSMDDMMKVRNLGKKSLEEVEQKLEALGLGLRKSED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ARL2_DICDI
Sequence: MGLLTVLKKLKQKEKELRILMLGLDNAGKTTILKKFNGEDISTISPTLGFNIQTLMYKEYKLNIWDIGGQKTLRSYWRNYYEENDAVIWVIDSSDIRRIDDCKFELKKLLEEEKFAGASFLVFANKQDLDGAMTSEEISKYLDLEQLNTHHWEIMSCSAVTGLGLEEGIDWVVKDIVSRCFVLD
What is the function of this protein?
May be involved in trafficking events within the endosomal system.
What are the official names of this protein?
ADP-ribosylation factor-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
Protein: ADH_ZAPTU
Sequence: MVFXLPNKNVIFVAGLGGIGLDTSREIVKAGPKNLVILDRVENPAAIAELQAINPKVTVTFYPYDVTVPLSESVKLLKTIFDKLKTIDLLINGAGILDDHQIERTIAVNFTGLVNTTTAILQFWDKRKGGPGGVIANICSVTGFNAIYQVPVYSASKAAVVSFTQSIAKLAPITGVTAYSINPGITKTTLVHKFNSWLDVEPRVAELLDEHPTQSTTACAQNFVKAIELNQNGAIWKLDVGRLDPVQWTKHWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: DNAE2_RHOPS
Sequence: MKVPAYAEIGVTTNFSFLEGGSHPQDYVHEASRLGLEAIGIADRNTLAGVVRAYSELGNEDLIHKPRLLIGARLVFADGTPDVLAYPVDRAAYGRLCRLLSVGKLRGAKGECHLAVADLEAFSQGLSLVLMPPYRFQASAIAAALQRLTALESGGVWLGLTPYYRGDDKRRLARLKRVAWAARVPGIATNDVLYHHPERRALQDVLSCVREKTTIDKIGRRLEANAERHLKPAAEMARLFRADPDAIAETLRFAAGISFTLDELKYHYPDEPVPPGKTAQQHLEDLTWEGVAEYFPAGISDKLHATIDKELGIIAHRGYAQYFLTVHDIVRYARSQDILCQGRGSAANSAVCYVLGITCVDPTEIDLLFERFVSEERDEPPDIDVDFEHSRREEVMQYIYRRYGRHRAAIVATVIHYRPRSAIRDVGKALGLSEDVTAALADTVWGSWGKGLNEMQVKQAGLDPHNPLIGRAVELATELIGFPRHLSQHVGGYVLTQDRLDSYVPIGNAAMEGRTFIEWDKDDIDAIKMMKVDVLALGMLTCIRKGFDLIAQHKGVRYALSDIKSEDDNAVYQMLQRGESIGVFQVESRAQMNMLPRLKPKCFYDLVIEVAIVRPGPIQGDMVHPYLRRRNKQEPVVYPAPAGHAGDANELEVILGKTLGVPLFQEQAMRIAIEAAHFTPDEANQLRRAMATFRNVGTIGKFESKMVGNLVARGYDPVFAKNCFEQIKGFGSYGFPESHAASFAKLVYVSAWMKCEHPDAFCCALLNSQPMGFYAPAQIVGDARANEVEVRPVDVSFSDGQCTLEERCGKHHAVRLGFRQIDGFVWADPDEERVRREAGLLPSEDWAARIVAARARGPFNSLERFARLTALPKRALILLADADAFRSLGLDRRAALWAVRRLPDDVPLPLFEAASASEQLDENAAPLPQMPTAEHVVADYQTVRLSLKGHPMEFLRPLFAAERVVTCRSISESRVSGQRMRCAGVVLVRQRPGSAKGVVFITLEDETGIANLVVWPAVMETFRKEVMGARLLWVEGRIQASPEGVVHLVAERLSDRSFEMTRLSDNLAAPRLGELHEPLNDDRREHPDNPAQRIRHPRDVRILPPSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_LEPBJ
Sequence: MDIKEIALGQIRDSIATKQKCIDSILGDITKAGEMVSKVLQSGNTVYLCGNGGSSCDASHIAAELVVRYKSGNERKALPALSLSGDSAVLTACSNDYGYEEIFARQIEAFGRKGDLLIGLSTSGNSKNVLLALEKAKTRGVKTISLLGGDGGRIKNLSDLDIIVPSKVTARIQESHILIGHILCSIVEYNLFKME
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IKBA_PIG
Sequence: MFQPAEPGQEWAMEGPRDALKKERLLDDRHDSGLDSMKDEEYEQMVKELREIRLEPQEAPRGAEPWKQQLTEDGDSFLHLAIIHEEKALTMEVVRQVKGDLAFLNFQNNLQQTPLHLAVITNQPEIAEALLEAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQPRGTQHLHSILQATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEDELPYDDCVLGGQRLTL
What is the function of this protein?
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals.  On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
What are the official names of this protein?
NF-kappa-B inhibitor alpha, ECI-6, I-kappa-B-alpha, IkB-alpha, IkappaBalpha.
What is the protein family that this protein belongs to?
Belongs to the NF-kappa-B inhibitor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export.
Protein: TM163_BOVIN
Sequence: METAAGSERRSTPGPAVPPPPRGHAPLATASGPLSSPAREPPQPEEERQLRISESGQFSDGLEDRGLLESSTRLKPHEAQNYRKKALWVSWFSIIVTLALAVAAFTVSVMRYSASAFGFAFDAILDVLSSAIVLWRYSNAAAVHSAHREYIACVILGVIFLLSSVCIVVKAIHDLSTKLLPEVDDFLFSVSILSGILCSILAVLKFMLGKVLTSRALITDGFNSLVGGVMGFSILLSAEVFKHNSAVWYLDGSIGVLIGLTIFAYGVKLLIDMVPRVRQTRHYEMFE
What is the function of this protein?
May bind zinc and other divalent cations and recruit them to vesicular organelles.
What are the official names of this protein?
Transmembrane protein 163.
What is the protein family that this protein belongs to?
Belongs to the TMEM163 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Early endosome membrane. Note=Glutamatergic synaptic vesicles.
Protein: KHSE_MYCA9
Sequence: MSEVLPAGLATTVLVPASSANLGPGFDSLGIALSLYDEIEVNTTESGLKVAVEGQGAGEVPLDGSHLVVRAIERGLAAGGAAAPGLIVQCHNKIPHSRGLGSSAAAAVAGLGVANGLLAKAGRAVLSDDVLVQLASEFEGHPDNAAASVLGGAVVSWSETSGATPIYAATRLDVHPDIKIVAAIPEEQSSTAHTRVLLPQAVTHVDARFNISRVALLTVALTARPDLLMTATEDRLHQPQRASAMPASADVLAYLRSQGVAAVLSGAGPAVLALTTVDLPDSAVKYAEDQGFSLVAMAVSAGVSVR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHLB_ECO24
Sequence: MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHADAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEYIEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLTRPRTGNGPRRTGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.