PharMolix/UniProtQA huggingface dataset:
Protein: SYV_PROMP
Sequence: MNESNDELTLNNYLPSQVEQKWQKRWDSLRAFSPNPSDNGDPFCIVIPPPNVTGSLHMGHAFNTALIDVIIRFQRLLGKNVLCLPGTDHASIAVQTILEKQLKTEGKNSEDIGREEFLKRAWIWKEQSGGKIISQLKRIGYSVDWERERFTLDEKLNEAVVEAFNILHEKKLIYRGEYLVNWCPASQSAVSDLEVEMQEVNGYLWHFKYPLISDQGQILDKYLEVATTRPETLLGDTALAVNPNDERYKKYIDKKVKVPFVDREIPVISDIHVDKDFGTGCVKVTPAHDPNDFAIGKRNNLKQINIMNKDGTLNINAGKFQDLDRFDARKKIIKELDTLGLLTKIENYKNTVPFSDRGKVPIEPLLSTQWFLKMDNISSSCLKELDSKKPTFIPQRWEKVYKDWLDNINDWCISRQLWWGHQIPAWYVLKQSEDSIDQNTPYVVARNEKEALSKATKEFGSNLQLIRDKDVLDTWFSSGLWPFSTLGWPNINDADFKKWYPNSVLITGFDIIFFWVARMTMMGKTFTNNIPFKDVYIHGLVRDENNKKMSKSSGNGIDPLLLIDKYGSDALRFALLREVAGAGQDIRLDYDRKENTSSTVEASRNFANKLWNATKFVLINKTFSENCSLNESDEKNLELSDKWILSKLNQLNTKVSNLLIEYKLGESAKLLYEFAWNDFCDWYVEFAKQKFNNKETHNRKISEKILIKVLTDVLVMMHPFMPHITEELWHKLQIKPEQILLSLQKWPVLEKKYINSQIDKSFHELFEIIRLIRNLRVELGLKPSQLVPVYLISDNVELTNFLKTLIVDIKTFTKSSEVIICKSKDIDKNNFAQSFSGIIGDLEVYLPFNDFVNLEALKDRLTKDLKKVNSDIETLNKRISNKNFIDKAPKEIVDECFAKLKEGNLQSEIINKKLKLLK
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_BORPE
Sequence: MPSNPTRKGRVVVGMSGGVDSSVTAWLLKQQGYEVVGLFMKNWEDDDDSEYCSTRQDLLDAASVADLVGVEFEYVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMALGAEHIATGHYARVRTVETPAGPRHQLLKALDDTKDQSYFLHRLNQVQLARTLFPLGELRKTEVRRIAHEIGLHNAAKKDSTGICFIGERPFREFLNRYLPSEPGPILTPEGQRVGTHHGLSFYTLGQRKGLGVGGVKGRQRDDGTAEAWYAARKDLARNVLYVVQGHDHPWLLSAQLQAQDASWIAGEPPAAGAYGAKTRYRQADAACRLDQAGGERFALAFEQAQWAVTPGQSAVLYDGEVCLGGGIII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNHF2_STAAW
Sequence: MIQTITHIMIISSLIIFGIALIICLFRLIKGPTTADRVVTFDTTSAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSVSISRFIGGGHVFNGNNKRNL
What are the official names of this protein?
Putative antiporter subunit mnhF2, Mrp complex subunit F2, Putative NADH-ubiquinone oxidoreductase subunit mnhF2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLGC_STRZT
Sequence: MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGTSHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEASRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDFGKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYSRNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAIIGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: KC13_YEAST
Sequence: MSQRSSQHIVGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRKFSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYLISLMDDALRLNDLKDDGHYDWMDLNGGKGWNIKINRRANLHGYGNPNPRVNGNTARNNVNTNSKTRNTTPVATPKQQAQNSYNKDNSKSRISSNPQSFTKQQHVLKKIEPNSKYIPETHSNLQRPIKSQSQTYDSISHTQNSPFVPYSSSKANPKRSNNEHNLPNHYTNLANKNINYQSQRNYEQENDAYSDDENDTFCSKIYKYCCCCFCCC
What is the function of this protein?
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.
What are the official names of this protein?
Casein kinase I homolog 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Nucleus membrane; Lipid-anchor; Cytoplasmic side. Vacuole membrane; Lipid-anchor; Cytoplasmic side. Note=Targeting to the vacuolar membrane may depend on AP-3 pathway.
Protein: HSP90_ASPFU
Sequence: MSSETFEFQAEISQLLSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPTKLDTGKDLRIDIIPDKENKTLTIRDTGIGMTKADLINNLGTIARSGTKQFMEALSAGADISMIGQFGVGFYSAYLVADRVTVVSKNNDDEQYIWESAAGGTFTLTQDTEGEQLGRGTKIILHLKDEQTDYLNESRIKEVVRKHSEFISYPIYLHVLKETEKEVPDEEAEETKEEEDEEKKAKIEEVDDEEEEEKKKKKKTKTVKESKIEEEELNKTKPIWTRNPADITQEEYASFYKSLSNDWEDHLAVKHFSVEGQLEFRAILYVPKRAPFDLFETKKTKNNIKLYVRRVFITDDATDLIPEWLGFIKGVVDSEDLPLNLSRETLQQNKIMKVIKKNIVKKTLELFNEIAEDREQFDKFYSAFSKNIKLGIHEDAQNRQTLAKLLRYQSTKSGDEATSLADYVTRMPEHQKQIYYITGESIKAVAKSPFLDSLKQKNFEVLFLVDPIDEYAFTQLKEFDGKKLVDITKDFELEETEEEKAEREKEEKEYENLAKSLKNILGDKVEKVVVSHKLVGSPCAIRTGQFGWSANMERIMKAQALRDTSMSSYMSSKKTFEISPKSSIIKELKKKVEADGENDRTVKSITQLLFETSLLVSGFTIEEPASFAERIHKLVSLGLNIDEEAETTEEKATEEAAPAEATTGESAMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 90, 65 kDa IgE-binding protein, Heat shock protein hsp1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENOG_RAT
Sequence: MSIQKIWAREILDSRGNPTVEVDLHTAKGLFRAAVPSGASTGIYEALELRDGDKQRYLGKGVLKAVDHINSTIAPALISSGLSVVEQEKLDNLMLELDGTENKSKFGANAILGVSLAVCKAGAAEKDLPLYRHIAQLAGNSDLILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFRDAMRLGAEVYHTLKGVIKDKYGKDATNVGDEGGFAPNILENSEALELVKEAIDKAGYTEKMVIGMDVAASEFYRDGKYDLDFKSPADPSRCITGDQLGALYQDFVRNYPVVSIEDPFDQDDWAAWSKFTANVGIQIVGDDLTVTNPKRIERAVEEKACNCLLLKVNQIGSVTEAIQACKLAQENGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLMRIEEELGEEARFAGHNFRNPSVL
What is the function of this protein?
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons.  Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
What are the official names of this protein?
Gamma-enolase, 2-phospho-D-glycerate hydro-lyase, Enolase 2, Neural enolase, Neuron-specific enolase, NSE.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.
Protein: KDSB_YERPE
Sequence: MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDLDRVRAIMLNQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUD16_SHEEP
Sequence: MAGMRRLELAEALHLGPGWRHACHAMLYAPDPGLLFGRIPLRYAVLMQMRFDGRLGFPGGFVDLRDGSLEDGLNRELGEELGEAAAAFRVERADYRSSHAGSRPRVVAHFYTKLLTLEQLTAVEMGAPRARDHGLEVLGLVRVPLYTLRDRVGGLPAFLENTFIGNAREQLLEAVQNLGLLEPGSFAHLKISTPP
What is the function of this protein?
RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner.  Part of the U8 snoRNP complex that is required for the accumulation of mature 5. 8S and 28S rRNA.  Has diphosphatase activity and removes m7G and/or m227G caps from U8 snoRNA and leaves a 5'monophosphate on the RNA.  Catalyzes also the cleavage of the cap structure on mRNAs.  Does not hydrolyze cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG).  Also hydrolysis m7G- and m227G U3-capped RNAs but with less efficiencies.  Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species.  Binds to the U8 snoRNA; metal is not required for RNA-binding.  May play a role in the regulation of snoRNAs and mRNAs degradation.  Acts also as a phosphatase; hydrolyzes the non-canonical purine nucleotides inosine diphosphate (IDP) and deoxyinosine diphosphate (dITP) as well as guanosine diphosphate (GDP), deoxyguanosine diphosphate (dGDP), xanthine diphosphate (XDP), inosine triphosphate (ITP) and deoxyinosine triphosphate (ITP) to their respective monophosphate derivatives and does not distinguish between the deoxy- and ribose forms.  The order of activity with different substrates is IDP > dIDP >> GDP = dGDP > XDP = ITP = dITP.  Binds strongly to GTP, ITP and XTP.  Participates in the hydrolysis of dIDP/IDP and probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (By similarity).  Exhibits decapping activity towards NAD-capped RNAs and FAD-capped RNAs (By similarity).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
U8 snoRNA-decapping enzyme, IDP phosphatase, IDPase, Inosine diphosphate phosphatase, Nucleoside diphosphate-linked moiety X motif 16, Nudix motif 16, m7GpppN-mRNA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NUDT16 subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Note=Localized predominantly in the cytoplasm. Localized in nucleolus, and in a minor proportion in distinct foci in the nucleoplasm.
Protein: UBC3_ARATH
Sequence: MTTPAKKRLMWDFKRLQKDPPVGISGAPQDNNIMHWNALIFGPEDTPWDGGTFKLTLHFTEDYPNKPPIVRFVSRMFHPNIYADGSICLDILQNQWSPIYDVAAVLTSIQSLLCDPNPDSPANAEAARLFSENKREYNRKVIEIVEQSYV
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 3, E2 ubiquitin-conjugating enzyme 3, Ubiquitin carrier protein 3, Ubiquitin-conjugating enzyme E2-17 kDa 3, Ubiquitin-protein ligase 3.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: DUT_WIGBR
Sequence: MKKKVNIRILDKRFGKEFFLPKYFTDGSSGMDLRACIDKEINLNPNETVLISTGVSIDISDQKISGLILPRSGLSHKYGIILSNTIGLIDSDYQGPIMISMLNRSNKNFLISIGDRIAQIIFVPLIQIEWNIVNKFVKITNRKDMGFGHSGKN
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: CCA_IDILO
Sequence: MDVYLVGGAVRDKLLKLPVHERDWVVVGARAEDLLKQGFLQVGKDFPVFLHPSTREEYALARTERKSGKGHTSFDVFASPDVTLEDDLARRDLTINAIAQSEDGEIVDPYNGVQDIKARKLRHVSEAFTEDPLRVLRVARFAARFAHLDFTVAEETQQMLQEMSASQELSHLVPERVWREWEKSLLTQTPTVFLTLLRDIQALSQVLPGITADDSQLQRLQRTSAYSDSVTLRFASLFIEQETPESLKQFCRQLAIPNHYRDSALLARNHEDFITTPELPEKAQLAALLKQIDYWRRPEKLEQLLQLRQAEYSESKQQKSIAAQHKKLRSGAEKAAALNAGTLQQQGFTGKALGDALREQREQILAEALN
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 2 subfamily.
Protein: PUR7_ECOL6
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: PDXA_WIGBR
Sequence: MNKISRIIITPGEPAGIGFDLVVLISQKIWRSELVICCDPDILVKRAKDHGIKLKLHFYNKNLSPKVREKGELTIIPIKVNSNVTRGILNINNSYYVINTLTRACLGCINKEFSALVTGPVHKGIIKDSGIKFIGHTEFLAGFSLCKNPVMMLMYNSLRIALATNHIPIKDISKCINFNLIRKKLIVIFNSLRNIFKINNPCIYVCGLNPHAGESGHIGTEEINIIQPAISSLKYLPCKIIGPISADSIFQQKYLKDADAILAMYHDQGLPMIKYIGFRKSVNITLGLPFIRTSVDHGTALNIKNLNEISSKSMEKAISLAIDISQDNSIKK
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSZ_SALTI
Sequence: MVSSSTTVPRSGVYYFSQGWKLVTLPGIRRFVILPLLVNIVLMGGAFWWLFTQLDAWIPSLMSHVPDWLQWLSYLLWPIAVISVLLVFGYFFSTLANWIAAPFNGLLAEQLEARLTGATPPDTGILGIMKDVPRIMKREWQKLAWYLPRAIVLLVLYFIPGIGQTIAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKTMRAALRTQKVANMQFGALTSLFTMIPVLNLFIMPVAVCGATAMWVDCWRAKHALWK
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: L18A_LUPLU
Sequence: MGIFAFENEQSSTVAPAKLYKALTKDSDEIVPKVIEPIQSVEIVEGNGGPGTIKKIIAIHDGHTSFVLHKLDAIDEANLTYNYSIIGGEGLDESLEKISYESKILPGPDGGSIGKINVKFHTKGDVLSETVRDQAKFKGLGLFKAIEGYVLAHPDY
What is the function of this protein?
Class II ribonuclease (RNase) (By similarity).  Binds to cytokinins (By similarity).  Interacts with melatonin (By similarity).
What are the official names of this protein?
Protein LlR18A, LlPR10.1A.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PUR5_COXBU
Sequence: MQSMPDSTRHPPLSYCKAGVDIEKAADLVEAIKPIAKRTRRPGVLSGIGGFGGLFELPRGYKQPVLVSGTDGVGTKLKLAVELNRHDTIGIDLVAMCVNDVITTGAEPLFFLDYYATGHLNNEQAKQILTGIGAGCELAEVALIGGETAEMPGLYRQKDYDLAGFCVGVVEKEKIIDGSRVRVGDALIGIASSGPHSNGYSLIRKILARAKIPLSQSFENKSLADGLLAPTRIYVKTIKRLFSEINVHALAHITGGGLIENVPRVLPSYTQAVIDSNGWEWPAIFHWLQKQGKVPIEEMWRTFNMGVGMVLCLDKKEVRKTLELLAALGETAWILGEIQSSSEEQPRVTITP
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEP7_TRIVH
Sequence: MRFSVVFAAIAALSSVVTAERGCGAIPHKGFATELMEAMDNARASSFSNTTAANVTINTYFHVITDGNKGQINNDTLQKQIEVLNKDYSGTGFSFKLVGSERTNNAGWASGNDDFGMKSSLRKGGYDSLNVYFVPMLREGLLGFCHFPTKNPGKRQLIMDGCVINSNTVPGGSAQNYDEGRTTTHEVGHFMGLYHVFNDNGGGCQQDGDMVDDTPVQSKPSSGCPKGKDSCPQQGVDSIHNYMDYSYDSCLNEFSPGQIQRMQMLWKQFRAGNSNRSPKAMKPIIPSYVSDPVM
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.  Plays a pivotal role as a pathogenicity determinant during infections and contributes to the ability of the pathogen to persist within the mammalian host (By similarity).
What are the official names of this protein?
Extracellular metalloprotease TRV_07111.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_STAAU
Sequence: MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAPENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSDFVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity).  Specific for fully assembled 70S ribosomes (PubMed:23150671).
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1C_PANGI
Sequence: MKEQKWIHEGLITESLPNGMFRIRLDNEDMILGYVSGKIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKNSKD
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS15_MYCBT
Sequence: MALTAEQKKEILRSYGLHETDTGSPEAQIALLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLIKYISQIDVERYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: EFG_LEIXX
Sequence: MLTDLHKVRNIGIMAHIDAGKTTTTERILFYTGVNHKLGETHDGASTTDWMEQEKERGITITSAAVTCFWNKNQINIIDTPGHVDFTVEVERSLRVLDGAVAVFDAKEGVEPQSETVWRQADKYVVPRICFVNKMDKLGADFYFTVDTIISRLGAKPLVMQLPIGSESEFIGVVDLIEMRALVWPGDAKGDVTMGAKYEVQEIPADLQAKAEEYRAKLVETVAESDDALLEKFFGGEELTVAEIKGAIRTMTVNNEIYPVLCGSAFKNRGVQPMLDAVIDYLPSPLDVPAIEAHDPRDEEKVILRHADATEPFSALAFKVAVHPFFGRLTYVRIYSGRVDSGAQVINSTKGRKERIGKIFQMHANKENPVDFVTAGNIYAVIGLKDTTTGDTLSDPANEVVLESMTFPEPVIEVAIEPKTKADQEKLGTAIQKLAEEDPTFRTEQNQETGQTVIKGMGELHLDILVDRMKREFNVEANVGKPQVAYRETLRRTVEKHDYTHKKQTGGSGQFAKVQITLEPLEVTPETSYEFVNAVTGGRVPREYIPSVDAGIQDAMQVGVLAGFPTVGVKATLVDGASHDVDSSEMAFKIAGSMAYKEAARKANPVLLEPLMAVEVRTPEEYMGDVIGDLNSRRGQIQSMEDASGVKVVKVNVPLSEMFGYIGDLRSKTSGRAVYSMQFDSYAEVPKAVADEIVQKSKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLBA1_OLIMA
Sequence: MKVLIIFACLVVMASAVCNRLEQILVKTQWAQSYGEAENRAAFSRDLFSELFNIQGSSRALFSGVGVDDMNSAAFTAHCLRVTGALNRLISQLDQQATINADLAHLAGQHASRNLDASNFAAMGQAVMSVVPTHLDCFNQHAWGECYERIASGISG
What is the function of this protein?
The extracellular giant hemoglobin is able to bind and transport oxygen and hydrosulfide simultaneously and reversibly at two different sites.
What are the official names of this protein?
Extracellular giant hemoglobin major globin subunit A1, Major globin chain b.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURT_PROMS
Sequence: MKESIFSKKRILLLGSGELGKELVIESKRLGLEVIAIDRYEKAPAMQVADYSRVIEMGDKNILKNVIKEFKPDYVVPEIEALSIEALKELEDEGFNIVPNARTVEITMNRDKIRDLASKDLKIKTAKFDYIFEFDDLEKKADEIGFPLLLKPLMSSSGKGQSLVETKNDLQNAWKQAQANSRGKVKGVIIEEFINFDFEFTLLTVRKENGENIFCLPIGHLQSNGDYQCSWQPLEIKESLIIEAKRMTSRILNNLNGAGLYGVEFFIKGSEVIFSELSPRPHDTGMVTLVSQNINEFELHLRAFLNLPIPRIDLIEPSATRVILSNQEYLNPIYEGLYEALEFEKTKVLIFGKPVSRKGRRMGVVLSSNTDINLARKNADEAALKIKVSTT
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.