PharMolix/UniProtQA huggingface dataset:
Protein: AGL14_HALVD
Sequence: MYAFVTGANGLLGSVVVRTLREQGHAVVGSYHSEEPTFDCPLHQVDITDTERVVELLDEYDVDLVINCAAYTDVDGCESNPEVATAVNGTAPGDLAAVCDDREIPFIHYSTDYVFDGETDGFYEEGDEPAPIQEYGRSKLTGEHAVRDVNPDALILRLSFVYGARGDTSDLVGFPQWVASTLAAGDTVPLFTDQTMTPSRAGNVATTTLELLDAGVSGTFHVASQSAVTPSDFGEKICEVIGGDATLIESSVMADLDRPAARPRRSCLDVSNVEGELGCSQPTLEDDLAALEAAFSDYSS
What is the function of this protein?
Reductase involved in N-glycan biosynthetic pathway that takes place under low-salt conditions (1. 75 M instead of 3. 4 M).  Participates in the formation of the tetrasaccharide present at 'Asn-532' of S-layer glycoprotein Csg, consisting of a sulfated hexose, 2 hexoses and rhamnose.  Involved in the addition of final rhamnose (sugar 4) of the tetrasaccharide on the dolichol phosphate carrier.
What are the official names of this protein?
Probable low-salt glycan biosynthesis reductase Agl14.
What is the protein family that this protein belongs to?
Belongs to the dTDP-4-dehydrorhamnose reductase family.
Protein: KARG0_SCYPA
Sequence: MADAAVIEKLEEGFKKLEAATDCKSLLKKYLTKSVFDQLKGKKTSLGATLLDVIQSGVENLDSGVGVYAPDAEAYTLFAPLFDPIIEDYHKGFKQTDKHPNKDFGDVNQFVNVDPDGKFVISTRVRCGRSMEGYPFNPCLTEAQYKEMESKVSSTLSNLEGELKGTYYPLTGMTKDVQQKLIDDHFLFKEGDRFLQAANACRYWPTGRGIYHNDNKTFLVWCNEEDHLRIISMQMGGDLGQVYRRLVSAVNEIEKRVPFSHHDRLGFLTFCPTNLGTTVRASVHIKLPKLAANREKLEEVAGKYSLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFQAVKEMQDGILELIKIEKEMQ
What is the function of this protein?
Catalyzes the reversible transfer of high energy ATP gamma-phosphate group to L-arginine.
What are the official names of this protein?
Arginine kinase Scy p 2.0101, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: PANC_RUTMC
Sequence: MQLCYQNTQITKLVNNWHTQGKTVAFVPTMGGLHQGHLSLIDIAKQKADKVIVSIFVNPAQFSKNEDLDSYPRTINADLTALKVNVDGVFIPNIKQIYPKGISKYIDVGKIGQILCGRTRPHFFNGVAQVVEILFGIVRPDVAVFGQKDYQQLLVIKQMVKNLSLNICIESGEIIREKSGLAMSTRNQYLSKNEAKIATNLHKTLSYFKHEILQNKKVYVLNELAKLDLKQHFKIDYLEVLDANNLKQITDNTHQIVILSAVFLGSVRLIDNIIFKKG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP2_MIZYE
Sequence: ASMFKHDHYMDNGVRYPNGDGICEQLNETKCDAGFSYDRSICEGPHYWHTISKCFIACGIGQRQSPINIVSYDAKFRQRLPKLKFKPHMEKLKTEVTNHQNRAPEFEPEDGENLYVKLNNLVDGHYKFHNLHVHNGRTRRKGSEHSVNGRFTPMEAHLVFHHDDQTHFEPTRTKLGGAFPGHNDFVVVGVFLEVGDDGFGDEPDDEECKRILKGHHPDNNENGNGDNGNNGYNGDNGNNGDNGNNGYNGDNGNNGVNGNNGYNGDNGNNGDNGNNGYNGDNGNNGDNGNNGENGNNGENGNNGENGHKHGCRVKKAKHLSTILECAYRNDKVREFKKVGEEEGLDVHLTPEMPLPPLKNRHYYTYEGSLTTPPCTESVLWVVQKCHVQVSRRVLHALRNVEGYKDGTTLRKYGTRRPTQKNKVTVYKSFK
What is the function of this protein?
Acts as a negative regulator for calcification in the shells of mollusks.  May function both as a calcium concentrator and as a carbonic anhydrase required for production of carbonate ions, which are assembled to CaCO(3) at mineralization sites.  Is important for shell formation in both the calcitic prismatic layer and the aragonitic nacreous layer (By similarity).  Shows inhibitory activity of crystal formation when present in free state but, when attached to the insoluble matrix, may regulate the form and size of aragonite crystal.
What are the official names of this protein?
Nacrein-like protein P2.
What is the protein family that this protein belongs to?
Belongs to the alpha-carbonic anhydrase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: XERS_STRZT
Sequence: MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKEYDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQKLFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLDLRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLYRGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDSL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CS073_HUMAN
Sequence: MRLKVGFQGGGCFRKDALCLEGGVSARWARAPHSAPLRPPRELHAAPPPATPTQTVVRPAGFPRRTRLMVRSAPPTQRPPTGSGCVSGLWRKGLGLRPQTLLRVGSVVLSSAPALRPRLGPCLRPPPSD
What are the official names of this protein?
Putative uncharacterized protein C19orf73.
Protein: RL17_UREU1
Sequence: MSYINKPGKTRAWRKMVSRQQVSDVISHGSIVTTKTKAKESQRHVDHLITLAKKNTLASRRAAAAILLGTNQHSADDLLRKLFNELGPKYANRAGGYTRVIKLGNRPGDNTEEAVLQLV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PEPQ_ECOL6
Sequence: MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPNSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: ATPE_PASMU
Sequence: MSVFNLTVVSAEQQIFSGQVESIQATGIEGELGILAGHTPLLTAIKPGIVKLTLEDGKEEVIYVSGGFLEVQPNVVTVLADTAIRGDELDGDRILAAKKRAEENIRTRHGDANYEMLASKLSKELAKLRAYELTEKLVKNKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNH_PROMA
Sequence: MTKKHGRIIAAATDGACSGNPGPGGWGALIRFEDGSVQEFGGFETNTTNNRMELTAALEVLKKLRDFDRDPHLRIRTDSKYLIDGFETWIKGWKKKGWRTASGKQVLNQDLWEALDQYRLANVRLEYVKGHSGDPDNERVDDIAVSFSKKIAIQLQCDHHIQNEK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA1_ACAM1
Sequence: MVSIRPDEISNIIRQQIEQYDQQVKVDNVGTVLQVGDGIARVYGLEQAMAGELLDFEDGTVGIALNLEEDNVGAVLMGDGRDLQEGSTVRSTGKIAQIPVGDALIGRVLDALARPIDGKGDINTSETRLIESPAPGIIERKSVYEPMQTGITAIDSMVPIGRGQRELIIGDRQTGKTAVAIDTILNQKSEDVICVYVAIGQKASTVAQVVEVLRERGALDYTVVVAANANDPATLQYLAPYTGAAIAEYFMYNGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSPELGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINAGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDQATQNQLARGARLREILKQPQYSPLPVEEMVAVIYAGTNGYLDDVPTDKVTEFVQGMRDDLKANHAKYGELVRSEKKMGDEAEGILKTAIADFKKSFMAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 1, ATP synthase F1 sector subunit alpha 1, F-ATPase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: PYRD_RHOE4
Sequence: MYQLLLSLMFRVPPERIHHIAFTAMKLVTRFAPLRWLVAKVLVVDDPVLRSQAFGLTFPAPLGLAAGFDKDATGVDAWGPLGFGFAEVGTVTAQAQPGNPAPRLFRLPADRALINRMGFNNHGAGHAANFLRQRRVTVPIGANIGKTKIVEAVDAAADYTASAQLLGPLADFMVVNVSSPNTPGLRDLQAVESLRPILQAVLDTVSVPVLVKIAPDLSDEDVDAVADLAVELGLAGIVATNTTIRRDGLKTPDAEVAALGAGGLSGAPVADRSLEVLRRLYARVGDKMTIISVGGIETADQAWERILAGATLVQGYTGFIYGGPFWARSIHKGIAKRVRAAGFSSIAQAVGAENPR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PLM10_PLAFO
Sequence: MKRISPLNTLFYLSLFFSYTFKGLKCTRIYKIGTKALPCSECHDVFDCTGCLFEEKESSHVIPLKLNKKNPNDHKKLQKHHESLKLGDVKYYVNRGEGISGSLGTSSGNTLDDMDLINEEINKKRTNAQLDEKNFLDFTTYNKNKAQDISDHLSDIQKHVYEQDAQKGNKNFTNNENNSDNENNSDNENNSDNENNLDNENNLDNENNSDNSSIEKNFIALENKNATVEQTKENIFLVPLKHLRDSQFVGELLVGTPPQTVYPIFDTGSTNVWVVTTACEEESCKKVRRYDPNKSKTFRRSFIEKNLHIVFGSGSISGSVGTDTFMLGKHLVRNQTFGLVESESNNNKNGGDNIFDYISFEGIVGLGFPGMLSAGNIPFFDNLLKQNPNVDPQFSFYISPYDGKSTLIIGGISKSFYEGDIYMLPVLKESYWEVKLDELYIGKERICCDEESYVIFDTGTSYNTMPSSQMKTFLNLIHSTACTEQNYKDILKSYPIIKYVFGELIIELHPEEYMILNDDVCMPAYMQIDVPSERNHAYLLGSLSFMRNFFTVFVRGTESRPSMVGVARAKSKN
What is the function of this protein?
During the asexual blood stage, processes key proteins essential for merozoite egress and invasion of host erythrocytes (PubMed:29074774).  Cleaves and activates proteases SUB1 and SUB2 (PubMed:29074774).  May process members of the EBL and Rh protein families (By similarity).  Also cleaves apical membrane protein AMA1 (By similarity).  During the mosquito vector stage and probably in ookinetes, cleaves CelTOS (By similarity).
What are the official names of this protein?
Plasmepsin X, Plasmepsin 10.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=In schizonts, localizes to exonemes which are secretory vesicles that discharge their content during egress into the parasitophorous vacuole.
Protein: MAT_INCAA
Sequence: MAHEILIAETEAFLKNVAPETRTAIISAITGGKSACKSAAKLIKNEHLPLMSGEATTMHIVMRCLYPEIKPWKKASDMLNKATSSLKKSEGRDIRKQMKAAGDFLGVESMMKMRAFRDDQIMEMVEEVYDHPDDYTPDIRIGTITAWLRCKNKKSERYRSNVSESGRTALKIHEVRKASTAMNEIAGITGLGEEALSLQRQTESLAILCNHTFGSNIMRPHLEKAIKGVEGRVGEMGRMAMKWLVVIICFSITSQPASACNLKTCLKLFNNTDAVTVHCFNENQGYMLTLASLGLGIITMLYLLVKIIIELVNGFVLGRWERWCGDIKTTIMPEIDSMEKDIALSRERLDLGEDAPDETDNSPIPFSNDGIFEI
What is the function of this protein?
Ion channel, which might have a role in genome packaging and uncoating processes.
What are the official names of this protein?
Polyprotein p42.
What is the protein family that this protein belongs to?
Belongs to the influenza C protein M1 family.
What are the subcellular locations of this protein?
[Polyprotein p42]: Host endoplasmic reticulum membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Protein M1']: Virion membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Protein CM2]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
Protein: MDTI_ECOLI
Sequence: MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAGMIMVKLA
What is the function of this protein?
Catalyzes the excretion of spermidine.  Can also confer resistance to deoxycholate and SDS.
What are the official names of this protein?
Spermidine export protein MdtI.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtI subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHBG_ECO55
Sequence: MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRIDRQPLSNSGDLPANLRSSQGFSSAFYGEEISEALFLQVLDDASHRGDLSLEVMCHPAFIDNTIRQSAYCFPRLTELEVLTSASLKYAIAERGYRLGSYLNV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OVCH2_HUMAN
Sequence: MLISRNKLILLLGIVFFERGKSATLSLPKAPSCGQSLVKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIVSPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLKMAGAFQFGHFVGPICLPELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWGLGCGRGWRNNVRKSDQGSPGIFTDISKVLPWIHEHIQTGNRRKSSRAWCSEQDVIVSGAEGKLHFPESLHLYYESKQRCVWTLLVPEEMHVLLSFSHLDVESCHHSYLSMYSLEDRPIGKFCGESLPSSILIGSNSLRLKFVSDATDNAARFNLTYKALKPNYIPDSGCSYLTVLFEEGLIQSLNYPENYSDKANCDWIFQASKHHLIKLSFQSLEIEESGDCTSDYVTVHSDVERKKEIARLCGYDVPTPVLSPSSIMLISFHSDENGTCRGFQATVSFIPKAGKKIELPTLWFPVLILVM
What is the function of this protein?
May be required for sperm ADAM3 processing and consequential sperm fertilizing ability (By similarity).  In vitro, has an endopeptidase activity (PubMed:32499443).
What are the official names of this protein?
Ovochymase-2, Oviductin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL1_MYCSJ
Sequence: MSKNSKAYREAAEKVDKTKLYSPLEAAKLAKETSSKKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGDKAEQAAAAGADIVGSDDLIEQIQGGMLDFDAAIATPDQMAKVGRIARILGPRGLMPNPKTGTVTADVAKAVSDIKGGKINFRVDKQANLHIVIGKASFDEKKLAENYGAALDEILRAKPSASKGRYLKKIVVSTTTGPGIPVDPQVTRNFAEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MDH_ACIBC
Sequence: MKQPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLEVPVEKAQQALKGVMMELDDCAFPLLAGMIGTDDPKVAFKDADYALLVGSRPRGPGMERADLLKVNGEIFIGQGQALNEVASRDVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHNRALTQVAQKAGVAVADIEKLTVWGNHSPTMYADYRFATANGESLKDKINDPAWNKDVFLPTVGKRGAAIIEARGLSSAASAANAAIDHMRDWALGTNGKWVTMGVPSDGSYGIPEGVMFGFPVTTENGEYKIVQGLEIDEFSRERINFTLNELEEERAAIADMVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: LRC26_RAT
Sequence: MRGSFFSRLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVAPVCPEACSCSPGGKANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAFKQCTQSLAARDLAVVYALGPASFLASLAICLALGSVLTACGARRRRRRTTVRHLIRRQPDPEGPASLEDVGSPTTTAIQA
What is the function of this protein?
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha).  Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells.  These are characterized by negative membrane voltages and constant low levels of calcium (By similarity).
What are the official names of this protein?
Leucine-rich repeat-containing protein 26, BK channel auxiliary gamma subunit LRRC26.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm, cytoskeleton. Note=Localizes to the cytoplasm when expressed at high levels.
Protein: G6PD_SCHPO
Sequence: MSSANLSIKENGAMVVFGASGDLSKKKTFPALFSLFSEGRLPKDIRIVGYARSKIEHEDFLDRITQNIKIDEEDSQAKEKLEEFKKRCSYYRGSYDKPEDFEGLNSHLCEREGDRSTHNRIFYLALPPDVFVSVATNLKKKCVPEKGIARLVIEKPFGVDLKSAQELQSQLAPLFDEKEIYRIDHYLGKEMVQNLVHLRFCNPVISHLWDKNSISSVQITFKEPIGTEGRGGYFDSSTIVRDIVQNHLVQILTLLTMETPTTFSADDLRDEKVKVLRRTRLGDLKDIVLGQYVKSKDGKKPGYLDDETVPKGSRCPTYSAIPCFIDTERWRGVPFLLKAGKAMDIGKVEIRVQFKAAANGLFKDAYHNELVIRVQPDEAIYFKMNIKQPGLSEAPLLTDLDLTYSRRFKNMKLHEAYEALFLDAFAGDQSRFARIDELECAWSLVDPLLKYMEEEKPVPEPYEYGSDGPECLYSFLKKFGYIYDSPDYYDYPVMSVPSDH
What is the function of this protein?
Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.  The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity).
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: XMT1_COFCA
Sequence: MELQEVLRMNGGEGDTSYAKNSAYNQLVLAKVKPVLEQCVRELLRANLPNINKCIKVADLGCASGPNTLLTVRDIVQSIDKVGQEKKNELERPTIQIFLNDLFPNDFNSVFKLLPSFYRKLEKENGRKIGSCLIGAMPGSFYSRLFPEESMHFLHSCYCLQWLSQVPSGLVTESGISTNKGSIYSSKASRLPVQKAYLDQFTKDFTTFLRIHSEELFSHGRMLLTCICKGVELDARNAIDLLEMAINDLVVEGHLEEEKLDSFNLPVYIPSAEEVKCIVEEEGSFEILYLETFKVLYDAGFSIDDEHIKAEYVASSVRAVYEPILASHFGEAIIPDIFHRFAKHAAKVLPLGKGFYNNLIISLAKKPEKSDV
What is the function of this protein?
Involved in the biosynthesis of caffeine (PubMed:17401201, PubMed:17434991).  Specific for xanthosine (PubMed:17434991).  Cannot use xanthosine 5'-monophosphate (XMP) as substrate (PubMed:17434991).  Directly produces 7-methylxanthine, and therefore the methyl transfer and nucleoside cleavage may be coupled (PubMed:17434991).  Catalyzes the 7-N-methylation of xanthosine, but does not have 1-N- or 3-N-methylation activity (PubMed:17434991).
What are the official names of this protein?
7-methylxanthosine synthase 1, Xanthosine methyltransferase 1, CcXMT1, XMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: GP168_BPPZA
Sequence: MIDIIVKEDKRLITVQTPEGDEVFYTLSFSDEHKLLKRSSARLRNNIYAIGVANIRWVLVDMDNMILSEYMHHVDILKDIDRKMRQLGYIVISEWQHANKKGTRR
What are the official names of this protein?
Gene product 16.8, gp16.8, Protein p16.8.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus gp16.8 family.
Protein: Y2392_LISMO
Sequence: MNPIVEFCVNNLASGADAAFAKLDADDNLDVIEYDCLTYCDLCATSLFALVDGEVVRGETAEELVANIYTFLEENPF
What are the official names of this protein?
UPF0349 protein lmo2392.
What is the protein family that this protein belongs to?
Belongs to the UPF0349 family.
Protein: DAPB_ARTOC
Sequence: MGANSRVNDDEAMPLTGHGAGSRDSIDSSSTASISLTLVDGASHTATEPSKSTNGHKSHTEGSYVNEKYHDSEEESWREDGYVPSGGKPAQRRTRIVFWLLVALCVGGWAMAFIIMATSPNNRHSTSDSSSGGSESEIVKPNTPHDGKKIPLDDVLGGMWGPVEHTISWISGPKGEDGLLLQKSEGGIGPYLHIEDVRNIHGMRANNNSIVLMKESVFFVNDERISPEKVWPSPDLKTVLAMTREKKNWRHSFTGLYWLFDVETQTAQPLDPEAPNGRVQLASWSPTSDAVVFTRDNNIYIRNLTSKAVKPITTDGGANLFYGIPDWVYEEEVFEGNSATWWSLDGKYISFLRTNETMVPEFPIDFYLSRPPGYTPEPGEEAYPYVQQIKYPKAGAPNPTVNLQFYDVEREESFSVNVDNNLKDDDRIIAEVIPASGGKMLVRETNRESYIVKVTVIDAAKREGKMVRSDNVDEIDGGWVEPSHSTTYIPSDPSAGRPHDGYIDTIIHEGYNHLAYFTPVENPKPMMLTTGNWEVVDAPSGVDLKNNVVYFVATKESPIDRHVYSVKLDGSELQMLNDSEKSAYYDVSFSNGAGYMLLKYQGPNIPWQKLISSPSNEDFYDEIIEENKNLARLSNEFSLPSLHYSTITVDGFKLPVVERRPPNFNETKKYPVLFHLYGGPGSQTVNKKFTVNFQTYVASNLGYLVVTVDGRGTGFNGRKFRCIVRRNLGYYEAHDQIQTAKEWGKKPYVDKTRIAIWGWSYGGFMTLKTLEQDAGETFQYGMAVAPVTDWRFYDSVYTERYMHMPQHNTEGYENASISNATSLSQNTRFLIMHGSADDNVHFQNTLTLLDKLDIMGMHNYDVHVFPDSNHGIYFHHAYKMVHQRLSDWLVNAFNGEWVRLRNPKPSGLKRVIRRLLHFG
What is the function of this protein?
Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Probable dipeptidyl-aminopeptidase B, DPAP B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9B family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass type II membrane protein. Note=Lysosome-like vacuoles.
Protein: RL7_RIPO1
Sequence: MSAATDQILEQLKSLTLLEASELVKQIEEAFGVSAAAPVGGGMMMMAPGGAAPAAAEPEEEKTEFDVVLEDVPADKKIAILKVVRAITGLGLKEAKDLVESAPKPIKEATNKDDAESIKKQLEEAGAKASVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: VLDLR_MOUSE
Sequence: MGTSARWALWLLLALCWAPRDSGATASGKKAKCDSSQFQCTNGRCITLLWKCDGDEDCADGSDEKNCVKKTCAESDFVCKNGQCVPNRWQCDGDPDCEDGSDESPEQCHMRTCRINEISCGARSTQCIPVSWRCDGENDCDNGEDEENCGNITCSADEFTCSSGRCVSRNFVCNGQDDCDDGSDELDCAPPTCGAHEFQCSTSSCIPLSWVCDDDADCSDQSDESLEQCGRQPVIHTKCPTSEIQCGSGECIHKKWRCDGDPDCKDGSDEVNCPSRTCRPDQFECEDGSCIHGSRQCNGIRDCVDGSDEVNCKNVNQCLGPGKFKCRSGECIDMSKVCDQEQDCRDWSDEPLKECHINECLVNNGGCSHICKDLVIGYECDCAAGFELIDRKTCGDIDECQNPGICSQICINLKGGYKCECSRGYQMDLATGVCKAVGKEPSLIFTNRRDIRKIGLERKEYIQLVEQLRNTVALDADIAAQKLFWADLSQKAIFSASIDDKVGRHFKMIDNVYNPAAIAVDWVYKTIYWTDAASKTISVATLDGAKRKFLFNSDLREPASIAVDPLSGFVYWSDWGEPAKIEKAGMNGFDRRPLVTEDIQWPNGITLDLVKSRLYWLDSKLHMLSSVDLNGQDRRIVLKSLEFLAHPLALTIFEDRVYWIDGENEAVYGANKFTGSELATLVNNLNDAQDIIVYHELVQPSGKNWCEDDMENGGCEYLCLPAPQINDHSPKYTCSCPNGYNLEENGRECQSTSTPVTYSETKDINTTDILRTSGLVPGGINVTTAVSEVSVPPKGTSAAWAILPLLLLVMAAVGGYLMWRNWQHKNMKSMNFDNPVYLKTTEEDLSIDIGRHSASVGHTYPAISVVSTDDDLA
What is the function of this protein?
Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism (PubMed:11108739, PubMed:24293365).  Binds also to a wide range of other molecules including Reelin/RELN or apolipoprotein E/APOE-containing ligands as well as clusterin/CLU.  In the off-state of the pathway LRP8 and VLDLR form homo or heterooligomers (By similarity).  Upon binding to ligands, homooligomers are rearranged to higher order receptor clusters that transmit the extracellular RELN signal to intracellular signaling processes by binding to DAB1 on its cytoplasmic tail (By similarity).  This interaction results in phosphorylation of DAB1 leading to the ultimate cell responses required for the correct positioning of newly generated neurons (PubMed:23506116).  Later, mediates a stop signal for migrating neurons, preventing them from entering the marginal zone (PubMed:17913789).
What are the official names of this protein?
Very low-density lipoprotein receptor, VLDL receptor, VLDL-R.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.