PharMolix/UniProtQA huggingface dataset:
Protein: EF2_METBF
Sequence: MGRRKKMVERVTMLMNEPTKIRNIGIVAHIDHGKTTLSDNLLAGAGMISKELAGRQLFMDSDEEEQERGITIDSSNVSMVHNFDNEDYLINLIDTPGHVDFGGDVTRAMRAVDGAVVVVDAVEGTMPQTETVLRQALREHVRPVLFVNKVDRLINELKVDSQEMQIRLGKVIDHVNKLIKNMNPEKYKEGWRVDAAAGTVAFGSALYNWAISVPMMKKTGVSFKDVYDYCKAGDMKSLAEKCPLHEAVLDMVIHFLPDPIEAQKDRVKVIWHGDENSEIGTSMTHANADGDLAFMVTDISVDPHAGEVATGRLFSGSFSRGMEVFTSGTAKKSRVQQVSIFMGPERLEVDKIPAGNIAAVTGLKEAIVGSTVTTLDGMEPFESIRHVSEPVVTVAVEAKHTKDLPKLIEVLRQVAKEDPTLQITLDEETGEHLMAGMGELHLEVIAHRIERDKNVEITTSKPIVVYRETIKKKIEPVEGKSPNRHNRFYIYVEPLDLEIVSAIKSGEIHMNLPELERRQKLIDLGMEKEEAKGIVGIFNSNIFIDMTKGIQYLNETMELILDGFEEVMRAGPLTREPVANVKCVLVDAKLHEDAIHRGPAQVIPASRQAIQAGMLMADDTLLEPYQKVFVQVPQLLMGGATKELQGRRGIILNMSTEGDLAIIEARVPVAEMFGFAGEIRSATEGRAMWSTEFGGFDIVPTSIQNDIVGQIRERKGLKKELPKASDFLSI
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor 2, EF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUF1_ASPFC
Sequence: MRGCLQLARWLSAAPKGTAASLTRAPFVLANAPRYFTSSASRAGSRSTATKPLSDLEKRISAIPIERYRNFCIVAHVDHGKSTLSDRLLELTGTIEPGSNKQVLDKLDVERERGITVKAQTCSMIYNHNGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGIQAQTVANFYLAFAQGLELIPVINKVDLPSAEPERALEQMKNSFELDTENAVMVSAKTGLNVEKLLPTVIEKIPAYGHFPVDSHELLPLLTLSSPIGDCKKPLRMLLVDSWYDSYKGVICLVRIFDGEIRAGQQVVSFATGLKYYVGEAGIMYPNETPQSVLRAGQVGYIYFNPGMKRSKEAKIGDTFTRVGFEKAVEPLPGFEEPKAMVFVAAYPVDADHFEHLEDSINQLVLNDRSITVQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPSVPVKIIWKDGKEEIITSPAKFPEDEELRSKVAEIQEPYVLATLTFPEEYLGKVIELCEANRGEQKSLEYFTPTQVILKYELPLAQLVDDFFGKLKGSTKGYASLDYEESAWQTGNIVKLQLLVNKAPVDAVARIVHSSQVERLGRQWVTKFKEHVDRQLFEVVIQAAVGKKIIARETVKPYRKDVLAKLHASDVSRRRKLLEKQKEGRKRLRAVGNVVIEHKAFQAFLAK
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor guf1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase guf1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: PAGC_SALTY
Sequence: MKNIILSTLVITTSVLVVNVAQADTNAFSVGYAQSKVQDFKNIRGVNVKYRYEDDSPVSFISSLSYLYGDRQASGSVEPEGIHYHDKFEVKYGSLMVGPAYRLSDNFSLYALAGVGTVKATFKEHSTQDGDSFSNKISSRKTGFAWGAGVQMNPLENIVVDVGYEGSNISSTKINGFNVGVGYRF
What is the function of this protein?
Essential for full virulence and survival within macrophages.
What are the official names of this protein?
Virulence membrane protein PagC.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. Ail family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CATA_VIGRR
Sequence: MDPYKYRPSSAFNSPFWTTNSGAPVWNNNNSLTVGTRGPILLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDVSHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNLPVFFVRDGMKFPDMVHALKPNPKNHIQENWRILDFFSHFPESLHMFSFLFDDLGVPQDYRHMDGFGVNTYTLINKAGKAVYVKFHWKTTSGVKCLLEEEAIKVGGANHSHATQDLHDSIAAGNYPEWKLFIQTIDPEHEDKFDFDPLDVTKTWPEDIIPLQPVGRLVLNKNIDNFFAENEQLAFCPAIIVPGVYYSDDKMLQTRIFSYADSQRHRLGPNYLLLPANAPKSAHHNNHHEGFMNFIHRDEEVNYFPSRYDPVRHAEKFPIPPAVFSGRREKIAIEKENNFKQAGERFRSWAPDRQDRFIRRWVDALSDPRVTHEIRSVWISYWSQADRSLGQKIASHLNMRPNI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: TNPO1_MOUSE
Sequence: MVWDRQTKMEYEWKPDEQGLQQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPDLLPKLCSLLDSEDYNTCEGAFGALQKICEDSAEILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIISRTQALMLHIDSFIENLFALAGDEEAEVRKNVCRALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALEACEFWLTLAEQPICKDVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQHEEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKELLFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVVSQPPDTYLKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKPEYIQMLMPPLIQKWNMLKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPEQYEAPDKDFMIVALDLLSGLAEGLGGNIEQLVARSNILTLMYQCMQDKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTNLNPEFISVCNNATWAIGEISIQMGIEMQPYIPMVLHQLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICTMISVNPSGVIQDFIFFCDAVASWINPKDDLRDMFCKILHGFKNQVGDENWRRFSDQFPLPLKERLAAFYGV
What is the function of this protein?
Functions in nuclear protein import as nuclear transport receptor.  Serves as receptor for nuclear localization signals (NLS) in cargo substrates (PubMed:11493596).  May mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity).  Involved in nuclear import of M9-containing proteins.  In vitro, binds directly to the M9 region of the heterogeneous nuclear ribonucleoproteins (hnRNP), A1 and A2 and mediates their nuclear import.  Involved in hnRNP A1/A2 nuclear export.  Mediates the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5 (By similarity).  In vitro, mediates nuclear import of SRP19 (By similarity).  Mediates the import of histones H2A, H2B, H3 and H4 (PubMed:11493596).  Mediates nuclear import of ADAR/ADAR1 in a RanGTP-dependent manner (By similarity).
What are the official names of this protein?
Transportin-1, Importin beta-2, Karyopherin beta-2.
What is the protein family that this protein belongs to?
Belongs to the importin beta family. Importin beta-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FPG_LACJO
Sequence: MPEMPEVETVRRTLTPLVKGKTIAKIIIWYPKIIVNNPDEFVEKLTNKKILKIDRYGKYLLFRFSDDLTMVSHLRMEGKYHLVTPDHPKGKHEHVEFVFTDGTALRYADVRKFGRMHLVETGTEKQTTGIRHLGPEPNTEEFSVEYFINALSRKKKNIKNTLLDQTVVCGLGNIYVDEVLWQSKIHPLSSAKSIPADKIVDLYHNINHTITVATKERGTTVHTYLDANGDIGGYQNMLQVYGHAGEECNNCGTILEKIKVNGRGTTFCPHCQVLYK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: NADE_BACC0
Sequence: MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLDESLTDFNKGNVKARIRMVTQYAIGGQKGLLVIGTDHAAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKTVPADVAEKIEKRYTVSEHKRQVPASMFDDWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: PSD_KLEP7
Sequence: MLNDLKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTAAYRTFNDFFVRPLRDDVRPLNTDPNVLVMPADGVISQLGAIENDKILQAKGHDYSLEALLAGNYQMADLFRNGSFATTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWSGTVTPPREGIIKRWTWPAGDNEGSIALLKGQEMGRFKLGSTVINLFAPGQVKLVDTLQSLSVTKIGQPLATAVEATAAAEPAPLPEEEIRAEHRASPLVDDKQDQG
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: VA0D_NEUCR
Sequence: MEGLLFNVNNGYIEGIVRGYRNSLLTSTNYTNMTQCESIDDLKLQLGPAYGDFLASLPPKPSTSALAAKTTDKLVSEFRYVRANAAGSLAKFMDYLTYGYMIDNVALLITGTLHERDTRELLERCHPLGWFETMPVLCVATNIEELYNSVMIETPLAPYFKSSLSLQDLDELNIEIVRNTLYKNYLEDFYHFVNTHPDMAGTPTAEVMSELLEFEADRRAINITLNSFGTELSKADRKKLYPNFGQLYPEGTLMLSRADDFEGVRLAVEGVADYKSFFDAAGLGGGPSGPGNMGGGGTEGKSLEDMFYQKEMEISKMAFTRQFTYAIVYAWVKLREQEIRNITWIAECIAQNQKERINNYISVF
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (By similarity).  This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector (By similarity).  Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit d, V-ATPase subunit d, V-ATPase 41 kDa subunit, Vacuolar proton pump subunit d.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein.
Protein: RRF_BACC0
Sequence: MGQQVLKSSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y242_HELPJ
Sequence: MFIVAVLMLAFLIFVHELGHFIIARICGVKVEVFSIGFGKKLWFFKLFGTQFALSLIPLGGYVKLKGMDKEENEENKINQANDSYAQKSPFQKLWILFGGAFFNFLFAVLVYFFLALSGEKVLLPVIGGLEKNALEAGLLKGDRILSINHQKIASFREIREIVARSQGELILEIERNNQILEKRLTPKIVAVISESNDPNEIIKYKIIGIKPDMQKMGVVSYSVFQAFEKALSRFKEGVVLIVDSLRRLIMGSASVKELSGVIGIVGALSHANSVSMLLLFGAFLSINLGILNLLPIPALDGAQMLGVVFKNIFHIALPTPIQNALWLVGVGFLVFVMFLGLFNDITRLL
What are the official names of this protein?
Putative zinc metalloprotease jhp_0242.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2876_CROS8
Sequence: MPSFDIVSEVDMREVQNAVENATRELETRFDFRNVTASFELNEKNQTIKVTSESDFQVNQLLDILRAKLLKRGIEGSSIEVPEEFDHSGKTWSVEAKLKQGIDSAMAKKIVKLIKDSKLKVQAQIQGEQVRVTGKARDDLQQTIALVRGGNLGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein ESA_02876.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RL19_STRPJ
Sequence: MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFEGVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RF1_ALKOO
Sequence: MLDKLAFLEEKYEDLSEKISEPEIINDQPQWKKLVKEHSDLEEIVMKYREYKKTEQGLNDAKEILRDKTADEEFREMAKMEIAELEEKIEVLEGELKILLLPKDPNDDKDVIVEIRAGAGGDEAGLFAADLFRMYTRYAENVGWKVEMMSANDTGIGGYKEVIFMIKGHGAYSRLKYESGVHRVQRIPSTESGGRIHTSTITVAVLPEADDVDFELDMNDIRVDVFRSSGNGGQSVNTTDSAVRVTHIPTGTVVSCQDEKSQLKNKEKALKILRARLLDVLIQEQQAEIAQDRKSQVGTGDRSERIRTYNFPQGRITDHRINVTLYRLDSFLNGDIQEMIDALITTDQAEKLKEVNS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 348R_IIV6
Sequence: MTHKYQILYDTLISKINASTNLEINELPILDDDGYDIMYQLYDMFMKKHNLPIKKFIIEEEENKDFDTITFDFKNMPNELKLLLYIFAETHYKALNNL
What are the official names of this protein?
Uncharacterized protein 348R.
Protein: PL_STRMK
Sequence: MSLPLRLALLPTLLASASAFAACPAPPPGQPDIRAIGYYTDKAGSVIDPALQQQNKDATAPLDRYAADVARMSDDYLRNGDPAAAQCTLSWLGAWADDGAMLGQMIRVNNDQSFYMRQWMLDAVAMAYLKVHDQANPQQRARIDPWLQKLARANLAYWDNPKRRRNNHYYWGGLGVLATGLATDDDALWQAGHAAFQKGIDDIQDDGSLPLEMARGQRALHYHDYALAPLVMMAELARLRGQDWYASRNHAIDRLARRVIEGSRDPAWFNQHTGAAQLPLQASGWVEFYRLRSPDGGVFDAAHARGPFHSPRLGGDLTLMATHGIVRTPLR
What is the function of this protein?
Polysaccharide lyase that catalyzes the depolymerization of several anionic polysaccharides via a beta-elimination mechanism.  Exhibits broad substrate specificity, catalyzing the degradation of not only alginate and poly-beta-D-mannuronate (poly-ManA), but poly-beta-D-glucuronate (poly-GlcA or poly-GlcUA) and hyaluronate (HA) as well.  The oligosaccharide products formed by enzymatic cleavage are comprised mainly of disaccharides, with a lower abundance of trimers and pentamers.  Is not active on poly-D-galacturonate, heparin and heparin sulfate.
What are the official names of this protein?
Polysaccharide lyase, PL, Alginate lyase, Endolytic polysaccharide lyase, Hyaluronate lyase, Multifunctional polysaccharide lyase, Poly-beta-D-glucuronate lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 5 family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: RS4_ALISL
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIDNAPGVHGARRGRLSEYGVQLREKQKVRRMYGVLEKQFRNYYKDAARIKGNTGENLLQLLEGRLDNVVYRMGFGSTRAESRQLVSHKSILVNGKVVNVPSFKVSANDVVSIREKAKLQSRIKAALEVAEQREKPTWIEVDAGKMEGTFKRLPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL9_STAAM
Sequence: MKVIFTQDVKGKGKKGEVKEVPVGYANNFLLKKNYAVEATPGNLKQLELQKKRAKQERQQEIEDAKALKETLSNIEVEVSAKTGEGGKLFGSVSTKQIAEALKAQHDIKIDKRKMDLPNGIHSLGYTNVPVKLDKEVEGTIRVHTVEQ
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: CC14C_HUMAN
Sequence: MRSSTLQDPRRRDPQDDVYVDITDRLRFAILYSRPKSASNVHYFSIDNELEYENFSEDFGPLNLAMVYRYCCKINKKLKSITMLRKKIVHFTGSDQRKQANAAFLVGCYMVIYLGRTPEAAYRILIFGDTPYIPFRDAAYGSCNFYITLLDCFHAVKKAMQYGFLNFNSFNLDEYEHYEKAENGDLNWIIPDRFIAFCGPHSRARLESGYHQHSPETYIQYFKNHNVTTIIRLNKRMYDAKRFTDAGFDHHDLFFADGSTPTDAIVKRFLDICENAEGAIAVHCKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGLVIGPQQQFLVMKQTSLWLEGDYFRQRLKGQENGQHRAAFSKLLSGVDDISINGVENQDQQEPKPYSDDDEINGVTQGDRSRALKRRRQSKTNDILLPSPLAVLTFTLCSVVIWWIVCDYILPILLF
What is the function of this protein?
Dual-specificity phosphatase.  Preferentially dephosphorylates proteins modified by proline-directed kinases (By similarity).
What are the official names of this protein?
Dual specificity protein phosphatase CDC14C, CDC14 cell division cycle 14 homolog C.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Note=Retains its endoplasmic reticulum localization during mitosis.
Protein: TRPF_RIPO1
Sequence: MRIKICGITQPDQGQAIAQLGATALGFICVPQSPRYVTPDQIQGVITQLSISVDRIGVFANASLSQIEQVVQQTELTGVQLHGDESPQLCSEIKQRFNHLELIKAFRVKNLEALAQITAYFDRVDTLLLDAYHPQLLGGTGHTLNWDNLAHFNPPLPWFLAGGLTPDNIQEALTRLHPTGIDLSSGVERSPGDKDLTKVAQLLTQLQQFSSKKFP
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: GPA5_CAEEL
Sequence: MGLVTCKQEREAELQNRQIDTQIRIENQANKRKIKMLLLGVTDSGKSTIVKQMRVNYLDGFNETEVVNAIFVIRNNIIDAFKNICNIILHSDITVTQEEKVLVKLFAYESGKIELMQEVDELNVINAVSGYECIKQFFERFAFHPMVPDHIHYFYPNLDRIASSNYVPTAEDLIHMRQTTLGVHEISFDYTKHIIRLIDVGGQKTERRKWIHFFEGVTAVMFVCSLASFNQTTEEEPKAFVWESSLNKVQNKVLVRSAGKAKVEKPGLINRLDESVDLFKSIRENSFLKMSNFMLFLNKKDLLTKKLTKVVFSDYFPDYKKWITNDNSDVSVAEFIENMFREGLEPEKRMYAHLTQATVTANIEGTFALCCDVIFGKNYEDTNLE
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-5 subunit.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: KLHDB_DROYA
Sequence: MGDLPGSGSTAQPRDAAVTGTGGNSTAGGGSSVGSTAVDRPPSPARLSHTSEKHPKVTLTELNMLRRHRELCDVVLNVGGRKIFAHRVILSACSSYFCAMFTGELEESRQTEVTIRDIDENAMELLIDFCYTAHIIVEESNVQTLLPAACLLQLVEIQDICCEFLKRQLDPTNCLGIRAFADTHSCRELLRIADKFTQHNFQEVMESEEFLLLPVGQLVDIICSDELNVRSEEQVFNAVMSWLKYNVAERRQHLAQVLQHVRLPLLSPKFLVGTVGSDLLVRSDEACRDLVDEAKNYLLLPQERPLMQGPRTRPRKPTRRGEVLFAVGGWCSGDAIASVERFDPQTNDWKMVAPMSKRRCGVGVAVLNDLLYAVGGHDGQSYLNSIERYDPQTNQWSCDVAPTTSCRTSVGVAVLDGFLYAVGGQDGVQCLNHVERYDPKENKWSKVAPMTTRRLGVAVAVLGGFLYAIGGSDGQCPLNTVERYDPRHNKWVAVSPMSTRRKHLGCAVFNNYIYAVGGRDDCMELSSAERYNPLTNTWSPIVAMTSRRSGVGLAVVNGQLYAVGGFDGSAYLKTIEVYDPETNQWRLCGCMNYRRLGGGVGVMRAPQTENYMWCENSFKQPNS
What is the function of this protein?
Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  May have a role in synapse differentiation and growth (By similarity).
What are the official names of this protein?
Kelch-like protein diablo.
Protein: EFP_SHEAM
Sequence: MKTAHEIRPGNVIMFNDSPWVVQKTETTRSGRNAAIVKMKLKNLLIDSSTETTFKGEDKMDVIVLERLDCTYSYFADPMYVFMDSEYNQYDVEAENVGDAAKYIVDGMEETCQVTFYEGKAISVEMPTTIIREVGYTEPAARGDTSGKVMKPAKLVGSDIELMVADFVKEGDKIEIDTRTGEFKKRVN
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US26_HCMVA
Sequence: MRQSYRYASGAVVRRTLKGLRKLILCQDLRQDIRHLVRSYADMNISLPISAPPGWRLDFVEFEDIFGSAAVTDGPETPWGQLICCEESLESLGVLQFSTTVLPRVHGPRSSSEDEDSDDDDFFVYVEEIEPPSQARLVLLLGRYETVWCLDRDRGVLYYLAHSLDDFARHGLLHCEAIYGEQMRTPLLTTQPDHIICDLRLHDNSISELQRVTCRYRGECVPLRTPGEMTRPLLLCGQAENLKGVWPFICMETEQFNDLLKFFVDRLCCETMIMGVVGESLPSGVFHADFVILVDRACEFFYFDVSRREIWRLADSVDMLLTVGLLKIYQAGRRFHYAVDDAERLEVPGRCPHENFPFWDRFGTVERVRASTRHHELRYKWLIRKDRFIVRPDWCSMRNSLDEVSGTADVSWDPRIRPDYPQTSDLECAKQYWQELNDHVREQTARYGPVRRYSVWCGMSSRLERAVKRLQQRIPRQNLMNPSLMNQGLCVYYSDEEEDQEEDDTSDDDDQEKETENPQNNIGSLTRTPSSPGSLEGVEERMLNVMKEAVAEQDRKKTQKKHKIDTAQRRVLTRRAARAAVLEGRPTPKPTMPHPVSYLPFWM
What are the official names of this protein?
Uncharacterized protein HHLF5.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US22 family.
Protein: SDC4B_XENLA
Sequence: MNRLLLLLALVLSGVAAESIRETETMDPTSMLEYESSGSFTDEVFVDEDDDDDYEDGVDYEIDSESDNDEDYSGSGDDDFDDEDNVEDEDEEETTTLGNQIPEHDFDETKTGRKFDTFNENNEIDNDIRHPAKPKTLEPSNEIPMASIGSSGFFQRTEVIVAIIAGTLVGLVVAVSFIVFLVIRRNQNGDLVKKPIYKKTSTMEV
What is the function of this protein?
Cell surface proteoglycan.  Regulates non-canonical Wnt signaling, being necessary and sufficient for fibronectrin-mediated translocation of dvl2/dsh to the plasma membrane.  Required for proper convergent extension movements during gastrulation, which shape the neural plate, and for subsequent neural tube closure.
What are the official names of this protein?
Syndecan 4-B, Syndecan-4.2, xSyn4.2.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NALD2_HUMAN
Sequence: MAESRGRLYLWMCLAAALASFLMGFMVGWFIKPLKETTTSVRYHQSIRWKLVSEMKAENIKSFLRSFTKLPHLAGTEQNFLLAKKIQTQWKKFGLDSAKLVHYDVLLSYPNETNANYISIVDEHETEIFKTSYLEPPPDGYENVTNIVPPYNAFSAQGMPEGDLVYVNYARTEDFFKLEREMGINCTGKIVIARYGKIFRGNKVKNAMLAGAIGIILYSDPADYFAPEVQPYPKGWNLPGTAAQRGNVLNLNGAGDPLTPGYPAKEYTFRLDVEEGVGIPRIPVHPIGYNDAEILLRYLGGIAPPDKSWKGALNVSYSIGPGFTGSDSFRKVRMHVYNINKITRIYNVVGTIRGSVEPDRYVILGGHRDSWVFGAIDPTSGVAVLQEIARSFGKLMSKGWRPRRTIIFASWDAEEFGLLGSTEWAEENVKILQERSIAYINSDSSIEGNYTLRVDCTPLLYQLVYKLTKEIPSPDDGFESKSLYESWLEKDPSPENKNLPRINKLGSGSDFEAYFQRLGIASGRARYTKNKKTDKYSSYPVYHTIYETFELVEKFYDPTFKKQLSVAQLRGALVYELVDSKIIPFNIQDYAEALKNYAASIYNLSKKHDQQLTDHGVSFDSLFSAVKNFSEAASDFHKRLIQVDLNNPIAVRMMNDQLMLLERAFIDPLGLPGKLFYRHIIFAPSSHNKYAGESFPGIYDAIFDIENKANSRLAWKEVKKHISIAAFTIQAAAGTLKEVL
What is the function of this protein?
Has N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity.  Also exhibits a dipeptidyl-peptidase IV type activity.  Inactivates the peptide neurotransmitter N-acetylaspartylglutamate.
What are the official names of this protein?
N-acetylated-alpha-linked acidic dipeptidase 2, Glutamate carboxypeptidase III, GCPIII, N-acetylated-alpha-linked acidic dipeptidase II, NAALADase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.