PharMolix/UniProtQA huggingface dataset:
Protein: GUAAA_ARCFU
Sequence: MKIYVIYNYGQYNHLIHRTLRDLGVETKLVENTTPVEQLKDVDGLVIGGGPSLDRTGNCELYLKELDVPMIGICLGHQLMAKVFGGEVGKGSMGGYSEVKVRIVEDDELFEGIPREITVWASHMDEVKKLPEGFKRLAESDICKIEAMRHEKKPLYGVQWHPEVYHSQFGVELYRNFIEICKK
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: MURI_STRMU
Sequence: MDNRPIGFLDSGVGGLTVVRELMRQLPHEEVIYIGDSARAPYGPRPAKQIKTYTWELVNFLLTKKVKMIVFACNTATAVVWEEVKEKLDIPVLGVILPGSSAAIKSTISGQIGIIGTPMTIKSNIYEQKIRDLSPQMKVRSLACPKFVPIVESNKMNSSVAKKIVYESLSPLVGKIDTLVLGCTHYPLLRPIIQNVMGPDVELIDSGAECVRDISVLLNYFDLNRSRTSKVLHHRFYTTASVASFKEIASDWLPLAIEVEHVTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: HSLV_BUCAP
Sequence: MTTILSVRLKNKVVIGGDGQATLGNTIMKSNVKKIRTLYHEKVIAGFAGGTADAFTLFEMFEKKLAMYQGQLPRAAIELAKDWRSDRMLRKLEALLAVADKDTSLIITGNGDVIQPEDDLIAIGSGGSYAQSAARALINNTTLNADEIVEKSLNIAANICIYTNHSFTIKELFSEK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WDFY1_HUMAN
Sequence: MAAEIHSRPQSSRPVLLSKIEGHQDAVTAALLIPKEDGVITASEDRTIRVWLKRDSGQYWPSIYHTMASPCSAMAYHHDSRRIFVGQDNGAVMEFHVSEDFNKMNFIKTYPAHQNRVSAIIFSLATEWVISTGHDKCVSWMCTRSGNMLGRHFFTSWASCLQYDFDTQYAFVGDYSGQITLLKLEQNTCSVITTLKGHEGSVACLWWDPIQRLLFSGASDNSIIMWDIGGRKGRTLLLQGHHDKVQSLCYLQLTRQLVSCSSDGGIAVWNMDVSREEAPQWLESDSCQKCEQPFFWNIKQMWDTKTLGLRQHHCRKCGQAVCGKCSSKRSSYPVMGFEFQVRVCDSCYDSIKDEDRTSLATFHEGKHNISHMSMDIARGLMVTCGTDRIVKIWDMTPVVGCSLATGFSPH
What is the function of this protein?
Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1.  Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed:25736436).
What are the official names of this protein?
WD repeat and FYVE domain-containing protein 1, FYVE domain-containing protein localized to endosomes 1, FENS-1, Phosphoinositide-binding protein 1, WD40- and FYVE domain-containing protein 1, Zinc finger FYVE domain-containing protein 17.
What are the subcellular locations of this protein?
Early endosome.
Protein: PI16_MOUSE
Sequence: MHGSCSPWVMLPPPLLLLLLLIATGPTTALTEDEKQTMVDLHNQYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNFSTATCDPNQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCENSLCEPMRNPEKAQDSPPRVTEVPSTRATEAPSSRETGTPSLATSETLHFSVTKVSDSLATESSPAVETKAPSSLATEGPSSMATEAQAFVTEVPLVSARHMQPSVDEGPVNFLTSTHIPVPKSMDEEASKSSATSVSPKKSLYPKMSLTESGESVPQIQEEAEPKDELSEPEAILPEAEAAPTEAEVELREPEAESPKAESPEAEAESPLSSEALVPVLPAQERGGQKASLEHSGHPASPSLPTFPSASGNATGGRTLALQSSWTGAENPEKADWDLKNSAHVWGPFLGLLLPSLLLLAGMV
What is the function of this protein?
May inhibit cardiomyocyte growth.
What are the official names of this protein?
Peptidase inhibitor 16, PI-16, Cysteine-rich protease inhibitor.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: HSLV_SINFN
Sequence: MSEHNPYGTMHATTIITVRKGGKVVMAGDGQVSLGQTVMKGNARKVRRLSKGDVIAGFAGATADAFTLLERLEAKLEQYPDQLMRAAVELAKDWRTNKYLRNLEAMMLVADKSVTLAITGNGDVLEPEHGTIAIGSGGNYAFAAARALMDSDKSAEEIARRALQIAGDICVYTNHNVVMETLDAD
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_SHESM
Sequence: MTQASAKFIVVEGLEGAGKSSAIALIRDFIEKHTGLAPVCTREPGGTPLAERIRDLVKIADPSDPLCDESECLLIYAARAQLVANVIKPALAEGKWVLGDRHNLSSLAYQGGGRGLMPLVEAVSNATLKGFKPDLTLYLDLDPKLGLQRAAKRGELDRIEQQAIDFFERARATYLKLASEDEQIVVIDASQTMAEVHKDILAVLQAMAW
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ARGC_TOLAT
Sequence: MLNVVIIGASGYAGAELALLVHKHPELNLKGLYVSAGSQDANKPFSALHPQCLGLVDLPVKPLDEAGMLEAKTGTDLVCLATAHEVSMNLAPQFLDAGIPVFDLSGAFRVQQDGFYDKYYGFTHDQPEWLAKAVYGLAEWNAEQIKKTDLVAVAGCYPTASLLALKPLMEAGLIKADTTPIINAVSGVSGAGRKAAIGTSFCEVSLNPYGVFNHRHQPEISYHLGGKVVFQPHLGNFVRGILATIYVQLADGVTAEQIDAAYQQAYSHSPIVRLSKQWPSIRSVAGTPFCDLHWQMQDGLLIVGSAIDNLLKGASSQALQCINLRFGFAPTTGLM
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO1A1_PARHA
Sequence: GGISVPGPMGPSGPRGLPGPPGPGPQGFQGPPGEPGEPGSGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGASGPAGARGNDGAAGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGRGPSGPQGPSGPGPKGNSGEPGAPGSKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGAPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPGPPGPVGKEGGKGPRGETGPAGRPGEVGPPGPPGPGEKGSPGADGPAGAPGTPGPQGIGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGSSGERGPPGPVGPPGLAGPPGESGREGSPGAEGSPGRDGSPGPKGDRGETGPGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPAGPAGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPAGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: GCSH_ACIAD
Sequence: MNHPSELKYATTHEWVRIEGDLIVTGISDHAQDALGDLVYVEVPEVGSHMTAGTQAGVVESVKTASDIHAPVSGTVVEVNTALEDDPDFINDEPYGKGWIYKMKPDNIADVDQLLSNTDYEAGL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: NDKB_FLABI
Sequence: MEHTFIMIKPDGVQRGLVGEIIGRFEKKGFSLKGLKLLTVDQAFAEKHYADLSAKPFFNGLVEYIISGPVVAMVWEGKNVVTTGRKIIGATNPAESAPGTIRGDFAIDIGRNVIHGSDAVESAKKEIALWFPEGVANWSSSLHPWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase B, NDK B, NDP kinase B.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: PDXA_YERP3
Sequence: MHNHNNRLVITPGEPAGVGPDLAIALAQQDWPVELVVCADPALLLARASQLNLPLQLREYQADQPAIAQQAGSLTILPVKTAVNVVPGKLDVGNSHYVVETLAKACDGAISGEFAALVTGPVQKSIINDAGIPFIGHTEFFADRSHCQRVVMMLATEELRVALATTHLPLLAVPGAITQASLHEVITILDNDLKTKFGITQPQIYVCGLNPHAGEGGHMGHEEIDTIIPALNTLRQQGINLIGPLPADTLFQPKYLQHADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALELAATGTADVGSFITALNLAIKMINNSNE
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_NEIMB
Sequence: MQNFGKVAVLMGGFSSEREISLDSGTAILNALKSKGIDAYAFDPKETPLSELKAQGFQTAFNILHGTYGEDGAVQGALELLGIPYTGSGVAASAIGMDKYRCKLIWQALGLPVPEFAVLHDDTDFDAVEEKLGLPMFVKPAAEGSSVGVVKVKGKGRLKSVYEELKHLQGEIIAERFIGGGEYSCPVLNGKGLPGIHIIPATEFYDYEAKYNRDDTIYQCPSEDLTEAEESLMRELAVRGAQAIGAEGCVRVDFLKDTDGKLYLLEINTLPGMTSHSLVPKSAAVTGVGFADLCIEILKTAHVG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_METHJ
Sequence: MVVVIDGDGLLLGRLASNVAKRALAGEEIAVVNAEKAVISGNRARVLGNYKQKRQRGSREGGPFFPRRPDHILKRTIRGMIPYKRERGIEAMKRIRIYVGVPDELSGQPFETIEDASKKRLGNPSHVTLGAVSTFLGAKY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: FIB_SPICI
Sequence: MIGVISTAYFTMKDKHSIKTVKKYWWKNCVIQHVKYHGKTFIIATVGYGKANAAMTITYLLEKYPGLQTILNVDLALSTNDKHDTGDTTISTKFIYRDADLTVFKDIKYGQIVNEPESFQFDGEFAKVVKDFKLGLTEGVTGTADMLIYNSKQFKEMVDKYGHTIDVIDTEAGAIAQVAKKSSINYIALKIIYNNALSPWDNDPIHKFKMYETVNTLKYLLRRLFNLLSSNYIIDLSQCSQDDLDSINELFEIKHDQWIKLFKPNTHKVLSGFGPSLMLVDKQEKTPVALDIIQVIRSKTKEAEGPSKVILGEDEWKNAPKKWLRKLLFLEQVRVNDDELLWNKSAKYDLNNEKLYKIETVETVANEIAAAIAEKCQDKSSYTYNGATVPEKYLLVNCDARISFYITHNQSHEFVEDKNFGTQLVSNEFLKYLNEALKDVDSPYQQIVIYMTIPALDYRKISVFIPSNKGANRGVKFVALNQKLQRDYTVVDITRNDYDPIKVGSFKVTIRLKSE
What is the function of this protein?
Acts as a cytoskeletal structure involved in the shape and motility of spiroplasmas.
What are the official names of this protein?
Fibril protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: KHSE_SHIF8
Sequence: MVKVYAPASSANMSVGFDVLGAAVAPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMK_NITOC
Sequence: MKIAVLSRNAKLYSTRRLVEAAKTRGHEVRVLDVLRCYMNIASHRPSIHYKGEDLTGFDAVIPRIGASVTFYGTAVLRQFEMIGVYPLSESVAITRSRDKLRSLQLLARKGIGLPVTGFAHAPDEIDDLIKMVGGAPVVIKLLEGTQGIGVVLAENKKAAQSVIEAFMGLKTHILVQEFIKETAGSDIRCFIIGDKVVAAMKRQAPEGEFRSNLHRGGSASLVRITPEERSTAIRAAQTMGLNVAGVDILRSNHGPLVMEVNSSPGLEGIESATGKDVATKVIEFIEKNATRGRTRTRGKG
What are the official names of this protein?
Probable alpha-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: MOAC_SOLM1
Sequence: MSEGFTHLDADGAARMVDVGGKTKTRRLAVAACEVHLSPATMALLATAALPKGDALNTAKIAGIMAAKRTADLIPLCHPLPLAHADVRFDVDQAAAVVRVEAEASTVAETGVEMEALTAAMVAALTIYDMCKAVQKDIVVSQAKLLFKSGGKSGTFVSPDWPAGRPYPAS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: LAR1B_HUMAN
Sequence: MENWPTPSELVNTGFQSVLSQGNKKPQNRKEKEEKVEKRSNSDSKENRETKLNGPGENVSEDEAQSSNQRKRANKHKWVPLHLDVVRSESQERPGSRNSSRCQPEANKPTHNNRRNDTRSWKRDREKRDDQDDVSSVRSEGGNIRGSFRGRGRGRGRGRGRGRGNPRLNFDYSYGYQEHGERTDQPFQTELNTSMMYYYDDGTGVQVYPVEEALLKEYIKRQIEYYFSVENLERDFFLRGKMDEQGFLPISLIAGFQRVQALTTNLNLILEALKDSTEVEIVDEKMRKKIEPEKWPIPGPPPRSVPPTDFSQLIDCPEFVPGQAFCSHTESAPNSPRIGSPLSPKKNSETSILQAMSRGLSTSLPDLDSEPWIEVKKRHQPAPVKLRESVSVPEGSLNQLCSSEEPEQEELDFLFDEEIEQIGRKNTFTDWSDNDSDYEIDDQDLNKILIVTQTPPYVKKHPGGDRTGTHMSRAKITSELAKVINDGLYYYEQDLWMEEDENKHTAIKQEVENFKKLNLISKEQFENLTPELPFEPNQEVPVAPSQSRQGGVQGVLHIPKKDLTDELAQKLFDVSEITSAAMVHSLPTAVPESPRIHPTRTPKTPRTPRLQDPNKTPRFYPVVKEPKAIDVKSPRKRKTRHSTNPPLECHVGWVMDSRDRGPGTSSVSTSNASPSEGAPLAGSYGCTPHSFPKFQHPSHELLKENGFTQQVYHKYRRRCLSERKRLGIGQSQEMNTLFRFWSFFLRDHFNKKMYEEFRQLAWEDAKENYRYGLECLFRFYSYGLEKKFRREIFQDFQEETKKDYESGQLYGLEKFWAYLKYSQSKTQSIDPKLQEYLCSFKRLEDFRVDPPISDEFGRKRHSSTSGEESNRHRLPPNSSTKPPNAAKPTSTSELQVPINSPRRNISPESSDNSH
What are the official names of this protein?
La-related protein 1B, La ribonucleoprotein domain family member 1B, La ribonucleoprotein domain family member 2, La-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the LARP family.
Protein: TRMB_STAAC
Sequence: MRVRYKPWAKDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEIGSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMGLTNLKIICNDAIELNEYFKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAYSLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSDKGSRIYRMEAKFHSQK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: FOLD_VIBVU
Sequence: MTAQNIDGTLISQTVRSEVAARVKARVAAGLRAPGLAVVLVGEDPASQVYVGSKRRACEEVGFVSKSFDLPASTSEEELLALIDELNNDAEIDGILVQLPLPAGIDSTHVLESIHPEKDVDGFHPYNVGRLAQRIPKLRSCTPKGIITLLERYNIALRGKHAVIVGASNIVGRPMTLELLLAGCTTTTCHRFTKDLEGHVRQADVLVVAVGKPNFIPGEWVKEGAIVVDVGINRLESGKLIGDVEYNKARERASFITPVPGGVGPMTVASLIENTMLACEQYHTK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ADH1_CLOSA
Sequence: MMRFTLPRDIYYGKGSLEQLKNLKGKKAMLVLGGGSMKRFGFVDKVLGYLKEAGIEVKLIEGVEPDPSVETVFKGAELMRQFEPDWIIAMGGGSPIDAAKAMWIFYEHPEKTFDDIKDPFTVPELRNKAKFLAIPSTSGTATEVTAFSVITDYKTEIKYPLADFNITPDVAVVDSELAETMPPKLTAHTGMDALTHAIEAYVATLHSPFTDPLAMQAIEMINEHLFKSYEGDKEAREQMHYAQCLAGMAFSNALLGICHSMAHKTGAVFHIPHGCANAIYLPYVIKFNSKTSLERYAKIAKQISLAGNTNEELVDSLINLVKELNKKMQIPTTLKEYGIHEQEFKNKVDLISERAIGDACTGSNPRQLNKDEMKKIFECVYYGTEVDF
What is the function of this protein?
This enzyme has activity using butanol and ethanol as substrates.
What are the official names of this protein?
NADPH-dependent butanol dehydrogenase, BDH.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: MYOD1_PIG
Sequence: MELLSPPLRDVDLTGPDGSLCNFATADDFYDDPCFDSPDLRFFEDLDPRLVHVGALLKPEEHSHFPAAAHPAPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAAFYAPGPLPPGRGGEHYSGDSDASSPRSNCSDGMMDYSGPPSGARRRNCYDGTYYSEAPSEPRPGKNAAVSSLDCLSSIVESISTESPAAPALLLADTPRESSPGPQEAAAGSEVERGTPTPSPDAAPQCPASANPNPIYQVL
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.  Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis.  Induces fibroblasts to differentiate into myoblasts.  Interacts with and is inhibited by the twist protein.  This interaction probably involves the basic domains of both proteins (By similarity).
What are the official names of this protein?
Myoblast determination protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2282_DEIRA
Sequence: MPTSRPRGIHQGAAAEARAAAHLESLGREIVRRNYRIPGGEIDLVSREPGGTLVFTEVRQRRQARYGSALDSVTPRKLALMHRAALEYLTRECGRDDLPCRLEVLTIEGEADTGELRLLAVEG
What are the official names of this protein?
UPF0102 protein DR_2282.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: CARB_STRZT
Sequence: MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEVVLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMELSKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAATIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEYEVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAELTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQLRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQGVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDLEQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQPPGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDHPVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQETIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVATKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAAFFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEHGVPLFTALDTANAMLKVLESRSFVTEAI
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: RBSD_LACJO
Sequence: MKKTGVMNSNISRVIADMGHMDWLGVGDAGTPVPAETEKIDLSVRPGLPSFIDVLEEVLKELEVQKMYIAEEIKTENPKQLEAIKRTVPNVEIEFIPHSELKKDLKSSKAFIRTGEETPYSNVILESGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_LEPIN
Sequence: MSAKNNIQDQLLNTARKDKLDLTIYLLNGVPLKGKVVSFDNFTIVLEQENKQSLVYKHAISTIIPAKIIKLYTEEAKDNKDAAQG
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: HIS1_ECOBW
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIT_ECOUT
Sequence: MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine.
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MPP8_MOUSE
Sequence: MAAAAEEGMSAAALVMSVPDSIGRSPESEGVGAGDEEKDAATKGTVAVGDSEEDGEDVFEVERILDMKCEGGKNLYKVRWKGYTSEDDTWEPEVHLEDCKEVLLEFRKKLAENKAKAVRKDIQRLSLNNDIFEADSDSDQQSDTKEDISPRKKKKKIKCKEETSPEDLRKKRTKMGKLKDKFKTELESTSEIIGFDVKTKKRIWEVKEELKDSKKPKKDEIKETKELKKANKRAEVRDLKIKIREDVKENRKTKKERYIESPLESESPNDSLILEDDSEDFISDNREENQNVRSVRDKTAQETVQEGIFEKHLDDLISIEEDAGTRVRRKKTKPRKFEEPKEIKKLESTNAFLERRAIPKKQRNQDKGISNLELNKLPSPVFAQTLKSSRLSGEEKSLKSPDLAEEEKEKKNEPKGKYQKRYDLDKEEKARKEPKVLKSFKEIRNAFDLFKKTTEEKNDVLENNSKREEISLDSKIMNDNKTKDKCSLKEKRNTRDETDTWAYIAAEGDQEVSDSVCQTDETSDGRQPVLSLGMDLQLEWMKLEDFQKHLDGEDEPFITTNRIPNNLLRDAVKNGDYIAVKVALNSNEEYNLDQEDSTGMTLVMLAAAGGQDDLLRLLITKGAKVNGRQKNGTTALIHAAEKNFLTTVAILLEAGAFVNVQQSNGETALMKACKRGNSDIVRLVIECGADCNILSKHQNSALYFAKQCNNVLVYELLKSHLETLSRVAEETIRDYFESRLALLEPVFPIACHRLCEGPDFSTDFNYMPPQNMPEGSGVLLFIFHANFLGKDVIARLCGPCSVQAVVLNDKFQLPVFLDSHFVYSFSPVAGPNKLFIRLTEAPFAKVKLLIGAYRVQLQ
What is the function of this protein?
Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression.  Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2.  Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene.  Mediates down-regulation of CDH1 expression.  Also represses L1 retrotransposons in collaboration with MORC2 and, probably, SETDB1, the silencing is dependent of repressive epigenetic modifications, such as H3K9me3 mark.  Silencing events often occur within introns of transcriptionally active genes, and lead to the down-regulation of host gene expression.  The HUSH complex is also involved in the silencing of unintegrated retroviral DNA by being recruited by ZNF638: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed.
What are the official names of this protein?
M-phase phosphoprotein 8.