PharMolix/UniProtQA huggingface dataset:
Protein: XERDL_STRPG
Sequence: MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLLYQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINTDIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLSQILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFILKEKLAGKSIIELSDILGLKSPVTLEKYYKS
What is the function of this protein?
Putative tyrosine recombinase.  Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site.
What are the official names of this protein?
Tyrosine recombinase XerD-like.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD-like subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLV_OLEA2
Sequence: MDLKGTTILAVKDDEGVSMAGDGQVTLGQAIVMKHGARKVRRIYKDRIIAGFAGSTADAFTLFERFEAKLEEFGGNLLRASVEMAKDWRKDKFLRRLEAMLLVSDGTTLLMLSGTGDVIEPDDGVAAIGSGGPYALAAARALQRHTALSAQEIVTKAMAIAGELCVFTNDHLTVENARRA
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_SHEPC
Sequence: MLKKDMNIADYDPELFNAIQNETLRQEEHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGGCEYVDVVETLAIERAKQLFGATYANVQPHSGSQANSAVYMALLKPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIIPYGIDESGKIDYDEMERIAIEHKPKMMIGGFSAYSGIVDWAKMREIADKIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTSTTHKTLAGPRGGVILSAADDEELYKKLNSAVFPGGQGGPLMHVIAGKAVAFKEALEPEFKVYQQQVVNNAKAMVEVFLERGYKIVSGGTSNHLMLVDLIGRDLTGKEADAALGSANITVNKNSVPNDPRSPFVTSGVRIGTPAITRRGFKEAEAKQLTGWICDILDDAHNPAVIERVKGQVLALCARFPVYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTL_JATCU
Sequence: TVLKTDAQCNCEAFKALSLP
What are the official names of this protein?
Non-specific lipid-transfer protein-like protein, Xylogen-like protein.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: SPEE_SALPB
Sequence: MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVETITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEALDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATNNDALRHLSSEIIQARFHAAGLKCRYYNPAIHAAAFALPQYLHDALSAQ
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2961_BACCZ
Sequence: MLGIDVKKTNEELIISWQIAKVQIPLSEIIEVTEDETYAGVEEENVIRIGTAYATTDRILIRTVKQNYLLFTTNKVAILNKINA
What are the official names of this protein?
UPF0457 protein BCE33L2961.
What is the protein family that this protein belongs to?
Belongs to the UPF0457 family.
Protein: CO9A2_MOUSE
Sequence: MTAVPAPRSLFVLLQVLWLALAQIRGPPGEPGPPGPPGPPGVPGSDGIDGDKGPPGKVGPPGSKGEPGKPGPDGPDGKPGIDGLMGAKGEPGPVGTPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGTPGPKGDPGPEGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPAGVKGPQGLQGVKGHPGKRGILGDPGRQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGEMGPRGYKGMVGSIGAAGPPGEEGPRGPPGEAGEKGDVGSQGARGPQGITGPKGITGPPGIDGKDGTPGIPGMKGSAGQVGRPGSPGHQGLAGVPGQPGTKGGPGDKGEPGQQGLPGVSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGIKGDKGSPGKTGPRGGVGDPGVAGLPGEKGEKGQSGEPGLKGQQGVRGETGYPGPSGDIGAPGVQGYPGLPGPRGLVGDRGVPGQPGRQGVVGRAASDQHIVDVVLKMIQEQLAEVAVSAKREALGAAGMVGLPGPPGPPGYPGKQGPNGHPGPRGIPGIVGAVGQIGNTGPKGKRGEKGDRGEMGHGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGRPGPVGLPGFCEPAACLGASAYTSARLTEPGSIKGP
What is the function of this protein?
Structural component of hyaline cartilage and vitreous of the eye.
What are the official names of this protein?
Collagen alpha-2(IX) chain.
What is the protein family that this protein belongs to?
Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ASPG_MYCBO
Sequence: MARLTVITTGGTISTTAGPDGVLRPTHCGATLIAGLDMDSDIEVVDLMALDSSKLTPADWDRIGAAVQEAFRGGADGVVITHGTDTLEETALWLDLTYAGSRPVVLTGAMLSADAPGADGPANLRDALAVAADPAARDLGVLVSFGGRVLQPLGLHKVANPDLCGFAGESLGFTSGGVRLTRTKTRPYLGDLGAAVAPRVDIVAVYPGSDAVAMDACVAAGARAVVLEALGSGNAGAAVIEGVRRHCRDGSDPVVIAVSTRVAGARVGAGYGPGHDLVEAGAVMVPRLPPSQARVLLMAALAANSPVADVIDRWG
What is the function of this protein?
Has a dual function in both nitrogen assimilation and in protection against acid stress during infection through asparagine hydrolysis and NH4(+) release.  Catalyzes asparagine hydrolysis.
What are the official names of this protein?
L-asparaginase, L-ASNase, L-asparagine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the asparaginase 1 family.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: NRNA_MYCTU
Sequence: MTTIDPRSELVDGRRRAGARVDAVGAAALLSAAARVGVVCHVHPDADTIGAGLALALVLDGCGKRVEVSFAAPATLPESLRSLPGCHLLVRPEVMRRDVDLVVTVDIPSVDRLGALGDLTDSGRELLVIDHHASNDLFGTANFIDPSADSTTTMVAEILDAWGKPIDPRVAHCIYAGLATDTGSFRWASVRGYRLAARLVEIGVDNATVSRTLMDSHPFTWLPLLSRVLGSAQLVSEAVGGRGLVYVVVDNREWVAARSEEVESIVDIVRTTQQAEVAAVFKEVEPHRWSVSMRAKTVNLAAVASGFGGGGHRLAAGYTTTGSIDDAVASLRAALG
What is the function of this protein?
Bifunctional enzyme which has both oligoribonuclease and pAp-phosphatase activities.  Degrades RNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 2-mers.  Also degrades 24-mers.  Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP.
What are the official names of this protein?
Bifunctional oligoribonuclease and PAP phosphatase NrnA, 3'(2'),5'-bisphosphate nucleotidase, 3'-phosphoadenosine 5'-phosphate phosphatase, PAP phosphatase, nanoRNase.
What is the protein family that this protein belongs to?
Belongs to the NrnA oligoribonuclease family.
Protein: MURE_SYNY3
Sequence: MVKLGQLLASVPEVVAAAPWLAQESDRCPALGKIVTGLSTNSHACPPGTLFIGMPGTRVDGGEFWSGALEAGAIAAVVSEKALQKFPPQNGECVIAVPDLVPVCAGLAAAFYQHPAQTLQLVGVTGTNGKTTTSHLIEYFLNQQQRSSALLGTLYTRWPGYQKTATHTTPFATDLQKQLAEALQAGNQYAVMEVSSHALAQGRVLQCGFACAVFTNLTQDHLDFHGTMENYFAAKALLFKESYLQGRAVINQDDPYGQRLIDRLPLDQVYTYSVNDSTADFYTKDLDYQPTGVKGTFVTPQGEFPFLSPLVGQFNLANVLAAIASGLHLGLDPAAMVKDLLDFPGVPGRMEQVQIRPDQDISVMVDYAHTPDSLENALKAARPFIPGRLICIFGCGGDRDRTKRPLMGNIAAQLADLAVVTSDNPRTEDPEQILADVVQGISLDIEPWIIGDRATAIHKAIREAKPGDGVLIAGKGHEDYQILGTEKIHFDDREQAREALILRYS
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y041_TREPA
Sequence: MNRMLSLSVQSQRAPASPSPYGLKIDKRVSPDYARAGVRS
What are the official names of this protein?
Uncharacterized protein TP_0041.
Protein: BUD32_PYRAB
Sequence: MKLIKQGAEAKIYLAEFSELYFDYPIKVIVKERIKKRYRIPEIDLKLRKERTIREARILRRAKEFGVNVPYVFEVDTKNMIIVMEYIEGERLKELLEKLPMEERLKVCREVGRQIGKLHEAGIVHGDLTTSNMILREGKVYFIDFGLAEFDDTIEAQGVDLHLLKRAMESTHYKWFERGFEEVLKGYIEIRGEDKGREIREKIREIELRGRYRERSWITQ
What is the function of this protein?
Component of the KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  Bud32 has ATPase activity in the context of the KEOPS complex and likely plays a supporting role to the catalytic subunit Kae1.
What are the official names of this protein?
KEOPS complex subunit Bud32, Atypical serine/threonine protein kinase Bud32.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. BUD32 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_SYLJO
Sequence: MNPMILLMLLITILSGTSIVMMSSHWFLTWLGFEMNMMAMIPVLMKKYNPRAMEAATKYFLTQATASMILVLGIIINLIHSGQWTIMAMESYSASTLLTIALVMKLGLAPFHFWVPEVTQGVSLNSGLILLTWQKIAPLSLLYQIYSSVNTNILLVMSLLSIMVGGWGGLNQTQLRKIMAYSSIAHMGWMIMIMIYNPNLSLLNLLIYILMTSSMFMLLMFNSTISTLALSRTWNINPIITTTILIILLSLGGLPPLSGFMPKWMIIQELTKNDSVILPAVMAILALLNLFFYMRLAYSSSLTMFPTTNNTKMVWQFQPMNVSFMMTSLISISIMALPLTPLAMILY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL22_XANCP
Sequence: MTMEAKAILRTARISPQKARLVADQVRGLSAERAVNLLKFSDKKAAHLIKKVVESAIANAENNQGADVDELKVKTIMVDEGPSLKRFMARAKGRGTRILKRTSHITVVVGAAK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DAPF_ECOLC
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_HALOH
Sequence: MSRIGKLPVDIPEKVDVSVNDNLVTVKGPKGELTKEFNNKKVTVEVKDGQVLVRRVHDKDKDARAFQGLTRSLIDSMVEGVTNGFEKKLEMVGVGYNAKKKGKDLELEVGYSHPVIIEAEDGIEFDVEKNNKIVVRGIDKQQVGEMAAKVRAVRKPEPYKGKGIRYEGEHIRRKEGKTG
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MRAY_YERPY
Sequence: MLVWLAEYLVKFYSGFNVFSYLTFRAIVSLLTALFISLWMGPHLIAWLQKLQIGQVVRNDGPESHFSKRGTPTMGGLMILFSITISVLMWAYPSNPYVWCVLFILIGYGIVGFIDDYRKVVRKNTKGLIARWKYFWQSIIALAAAFTMYSIGKDTSATELVVPFFKDIMPQLGLLYVLLAYFVIVGTSNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNVNFAAYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGTIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNR1_CAPAN
Sequence: MAEKTTSTRYAVVTGGNKGIGYETCRQLASKGVVVVLTSRDEKKGIEAIERLKEESNFTDEHILFHQLDIMDPASISSLVNLIKTKFGRLDILINNAGISGVMVEGDVQVLKEILERYISIVFTEDENGEEGGWTKSGPGSVTNYELTKECIETNYYGAKRMTEAFIPLLQLSNSPRIVNVASSMGKLKLLCNKWAIEVLRDADSLTEEKVDQVVNEFLKDFTEKSTESKGWPSYFTAYKVSKASLIAYTRVLATKYPNFRINSVCPGYCKTDVNANTGSLTAGEGAESLVNLALLPNDGPSGLFFYRKEVTFF
What is the function of this protein?
Involved in basal resistance against pathogens.
What are the official names of this protein?
(+)-neomenthol dehydrogenase, Menthone:neomenthol reductase 1, CaMNR1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: YDHJ_ECOLI
Sequence: MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQVSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKANNEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSGWVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKTLQGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSGTTCSIAVGQ
What are the official names of this protein?
Uncharacterized protein YdhJ.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ANP1_LYCDA
Sequence: NKASVVANQLIPINTALTLIMMKAEVVTPMGIPAEEIPKLVGMQVNRAVPLGTTLMPDMVKNYE
What is the function of this protein?
Contributes to protect fish blood from freezing at subzero sea water temperatures.  Lowers the blood freezing point.  Binds to nascent ice crystals and prevents further growth (By similarity).
What are the official names of this protein?
Ice-structuring protein RD1, ISP RD1, Antifreeze peptide RD1.
What is the protein family that this protein belongs to?
Belongs to the type-III AFP family.
What are the subcellular locations of this protein?
Secreted.
Protein: FUB5_GIBM7
Sequence: MSRRQTLKTLQKLILAPSQHISLSIASNLSVIPSRSMTTTATVPVLPTSIHDGLGKGIAYEKSLPRPVNPFSHRVPGREIITIPKFTLESGVEMRNVPVAYMSWGKLSSKANNVMIICHALSGSADVSDWWGPLLGHGKAFDTDKFFVICMNSLGSPYGTASPVTAKNGDYSEGWYGADFPSTTIRDDVRLHKLALDKLGVRKVAAAIGGSMGGMHVLEWAFFGKDYVRCIVPAATSSHQSAWAIGWGEAQRHAIRSDVKYKNGRYGFDDPPVLGLEAARMTALLTYRSRDSLERRFGRDTGSKKKTQKQESKTLPSNSTPIHSHSGADETPVAFDRADSSFAAQSYLRYQAKKFSNRFDSNCYIALTNKLDTHDLARGRTRTITEALSLIEQPTLVLGIRSDGLYTLAEQEQIARAVPNAKLREIVSDDGHDAFLIEWSQLNWLLIGFLHESLPDIMQRAAL
What is the function of this protein?
Homoserine O-acetyltransferase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties (PubMed:22652150, PubMed:25372119).  L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (By similarity).  The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (By similarity).  FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (By similarity).  Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the sulfhydrylase FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (By similarity).  Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (By similarity).
What are the official names of this protein?
Homoserine O-acetyltransferase FUB5, Fusaric acid biosynthesis protein 5.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
Protein: YEIN_SCHPO
Sequence: MRLRRLFKQPSTRVLGVTNCPRQQGHQKRREQPD
What are the official names of this protein?
Uncharacterized protein C27E2.14.
Protein: GLMU_CUPTR
Sequence: MNIVILAAGMGKRMYSDLPKVLHPVAGRPMLAHVLDTARALSPSRLVVVVGHGAARVREAVAADDVAFAEQAQQLGTGHAVMQALPLLDDNQPTLVLYGDVPLTSAATLQALVAEAGAQRFGVLTVEMPDPTGYGRIVRDAAGSIVRIVEQKDATEAEKAIREINTGIIVCPTGHLRKWLSTLRNDNAQGEYYLTDTVERAVADGVETVSAQPAAVWETLGVNSKLQLAEVERIHQGNQARRLLEAGVTLLDPARIDVRGELTCGRDVTIDVGCVFEGRVHLEDGVRIGAHCVIRNSTVGAGAQVHPFCHIDEAKVGPAGRIGPYARLRPGTELGEDVHIGNFVEVKNAQVAAHSKANHLAYVGDATVGSRVNIGAGTITCNYDGVNKHRTVIEDDVFIGSDTQLVAPVTVRRGATLGAGTTLTKEAPADKLTLSRAKQLTIDAWQRPVKQPKQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIR15_CAEEL
Sequence: MNFYSLFVFIALIFSFNVVHGHRCHRGGNGGYGGGSGEVVVIGAEKPKDK
What is the function of this protein?
May have role in hypoxia response.
What are the official names of this protein?
Fungus-induced-related protein 15.
Protein: CPH1_CANAL
Sequence: MSITKTYNGDPTSLVPTQSVKESLRLIEDLKFFLATAPANWQENQVIRRYYLNHDEGFVSCVYWNNLYFITGTDIVRCIVYKFEHFGRKIIDRKKFEEGIFSDLRNLKCGADAILEPPRSEFLEFLFKNSCLRTQKKQKVFFWFNVPHDKLMADALERDLKKEKMGQRPTTMAHREPALSFHYDESSSLYTQLGKHMETQKRINDAATSSTSNTATTLTDTGVSSGLNNTTSGGGSDSATSTHNNNEASTKPSNGSEKSSPEYTTTARGRDEFGFLNEATPSQYKANSDYEDDFPLDYINQTTQNSEDYITLDANYQAGSYANMIEDNYDSFLDATLFIPPSLGVPTGTAATATTSNQVAFNDEYLIEQAQPIRTPLPPISSSTISGLLQPKSAAKFFSLQSANGGEEFFPAYQNDPSTANAGFVPPISAKYATQFATRQVATPTYIKAIPQTGAAAATGNGGQPQQYYDQATGNAFYPAEIPVSYNVVHPESEYWTNNSGAVATTAAATAPMYDASGFPIPINQSYMVMNEHEMVPYQYMNSNGAMIGMIPPHQQQQQQQQQIAMGYQSMLRQQQQQQQQQQQQQPSSTMTKKKKQIHSFNNNKSLSSNGGGITKKSHDNNNHSKVKTSYGSLNDVVNSKVTKVINKEEVKQSQT
What is the function of this protein?
Transcription factor involved in the formation of pseudohyphae and hyphae.  It is likely to play a role in the developmental switch between yeast and mycelial forms.  May be involved in a signal transduction system, strengthening the possibility of a sexual phase up to now undetected, and similar to that of the yeast mating pathway.
What are the official names of this protein?
Transcription factor CPH1.
What is the protein family that this protein belongs to?
Belongs to the STE12 transcription factor family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPOP_BOVIN
Sequence: MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
What is the function of this protein?
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation.  In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3.  In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation.  Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation.  The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.  Involved in the regulation of bromodomain and extra-terminal motif (BET) proteins BRD2, BRD3, BRD4 stability.
What are the official names of this protein?
Speckle-type POZ protein.
What is the protein family that this protein belongs to?
Belongs to the Tdpoz family.
Protein: TMEDA_EMENI
Sequence: MGSSRLAMRSALGLFFLLFVQISLALKFDIAAGKGERCIRNFVLKDQLVVVTAIVSGERGDGQMVNMHIKDSMGNDHGRPKDVIGETRQAFTSAGDTTFDVCFENTLVSRRGISNPHRSIELDVDIGADARDWSNIQAQEKLKPIETDLRRIEEIVAEVVSEMEYLRAREQKLRDTNESTNERVKWFAFGTMGMLVGLGVWQVIYLRAYFRSKHLI
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: LIPL_EXISA
Sequence: MIHPLLQQPSYRIIDQSSLGTMFQAEQSFATDDTLCASTQERGAVLRAWVHTDTIVLGIQDARLPHLKEGIRYLHEQGFRPVVRNSGGLAVVLDDDVLNLSLILPEKDGIQIDSGYEAMTSLIQHMFQDVTNDIVPGEVVGSYCPGSFDLSIDGKKFAGISQRRVRGGVAVQIYLSVRQSGSARAEIIRDFYDLAIQGEETKFTYPTIVPETMASLEDLLGIPLTVQDVLTRAYRVLSTVSLLQNATLTADEQTMFASQLERMWKRNEPLRDIEQQLTEE
What is the function of this protein?
Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
What are the official names of this protein?
Octanoyl-[GcvH]:protein N-octanoyltransferase, Octanoyl-[GcvH]:E2 amidotransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipL family.
Protein: HFQ_MANSM
Sequence: MAKGQSLQDPYLNALRRERIPVSIYLVNGIKLQGQIESFDQFVILLKNTVNQMVYKHAISTVVPARSVSHHNNPQQQQQHSQQTESAAPAAEPQAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.