PharMolix/UniProtQA huggingface dataset:
Protein: KCNB2_HUMAN
Sequence: MAEKAPPGLNRKTSRSTLSLPPEPVDIIRSKTCSRRVKINVGGLNHEVLWRTLDRLPRTRLGKLRDCNTHESLLEVCDDYNLNENEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFGQELDYWGIDEIYLESCCQARYHQKKEQMNEELRREAETMREREGEEFDNTCCPDKRKKLWDLLEKPNSSVAAKILAIVSILFIVLSTIALSLNTLPELQETDEFGQLNDNRQLAHVEAVCIAWFTMEYLLRFLSSPNKWKFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREALERAKRNGSIVSMNLKDAFARSMELIDVAVEKAGESANTKDSADDNHLSPSRWKWARKALSETSSNKSFENKYQEVSQKDSHEQLNNTSSSSPQHLSAQKLEMLYNEITKTQPHSHPNPDCQEKPERPSAYEEEIEMEEVVCPQEQLAVAQTEVIVDMKSTSSIDSFTSCATDFTETERSPLPPPSASHLQMKFPTDLPGTEEHQRARGPPFLTLSREKGPAARDGTLEYAPVDITVNLDASGSQCGLHSPLQSDNATDSPKSSLKGSNPLKSRSLKVNFKENRGSAPQTPPSTARPLPVTTADFSLTTPQHISTILLEETPSQGDRPLLGTEVSAPCQGPSKGLSPRFPKQKLFPFSSRERRSFTEIDTGDDEDFLELPGAREEKQVDSSPNCFADKPSDGRDPLREEGSVGSSSPQDTGHNCRQDIYHAVSEVKKDSSQEGCKMENHLFAPEIHSNPGDTGYCPTRETSM
What is the function of this protein?
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain and smooth muscle cells.  Channels open or close in response to the voltage difference across the membrane, letting potassium ions pass in accordance with their electrochemical gradient.  Homotetrameric channels mediate a delayed-rectifier voltage-dependent outward potassium current that display rapid activation and slow inactivation in response to membrane depolarization.  Can form functional homotetrameric and heterotetrameric channels that contain variable proportions of KCNB1; channel properties depend on the type of alpha subunits that are part of the channel.  Can also form functional heterotetrameric channels with other alpha subunits that are non-conducting when expressed alone, such as KCNS1 and KCNS2, creating a functionally diverse range of channel complexes.  In vivo, membranes probably contain a mixture of heteromeric potassium channel complexes, making it difficult to assign currents observed in intact tissues to any particular potassium channel family member.  Contributes to the delayed-rectifier voltage-gated potassium current in cortical pyramidal neurons and smooth muscle cells.
What are the official names of this protein?
Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium channel subunit Kv2.2.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection, dendrite. Note=Localized uniformly throughout cell bodies and dendrites. Colocalizes with KCNB1 to high-density somatodendritic clusters on cortical pyramidal neurons.
Protein: ISPG_CITK8
Sequence: MHNQAPIQRRKSKRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRTVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIEQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMITQLEARIRAKASIMDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: YMZ2_YEAST
Sequence: MTNMAEDKTSISKVHSEFSNSSNTTGSEEESRSHQESFDGESSSGESKSKSKLNLEYSADIEPLKFRMTKTNNTNDKLKYSNNGNATDSFMRLKEHLQRGNTLNSNLRVNEFYPFNSIDTEQFENYLREPKYIKMLKRRKNLKQFRRLFLAQELMAYEGETVTSTSKSSEPTSKAIWSTKFSRDGKFMATGSKDGKIRIWKVIGSPVERAELDSSAESNKEARAKSMRIKQQVSSLNNPKEKQFLDSATEKYEEKEKLLNLYAPVFHPTPLRLYKEHVQDVLDINWSKNNFILSASMDKTVKLWHPDRKNSLKTFIHPDFVTCVEFHPTDDRFFISGCLDHKCRLWSILDDEVSFEYDCQDLITSVTLSPEEGKYTIIGTFNGYVHILMTRGLTPVSSFHVADRQTQEQNAHVMVTETDSKIRHGPRVTGLQAFRSQLDNSFRLVVTSNDSRIRIFDLEQRKLLEVLKGFHSGSSQHKAQLSIWHGQPIVVNSSDDHWVYGWRLKSSDRENDQDEPKRKPKGLARSGSLRSIFSKSMSRSSSQNNEEKPHHHLKLTNLLPLPHHSNDHYIKNTDYISFHAHNAPVTCVSIAPPETSKTLSLSNDVICELSLEFFQTSDSFDVLSRSNDDGIMSDVESSLGYNSKPGSISNASATSAIPDVVDAIGTILISTDNVGTIRVFRADMPSVIRKRVLLKLEEYNREVRRRFNSSDSLHSLSRSFNSRAKSNLAGQPAAAYTNTGKGYATGRGYSNICPKSSTSLKTLGSNAQPRTPRESMSSIFSNAHGPTTPTSAMNLPIRCNVCNGSRFEAFSGANDQQDRNYYCVDCGTVVNNFR
What are the official names of this protein?
WD repeat-containing protein YMR102C.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DGR2 family.
Protein: ENDA_METAC
Sequence: MKTQLEGDRVLAGKEAVAELYKTGYFGRPREDGLELSLVEAAYLQFRGKIEIELEGRKLDFRALFEQASLRQPNFELKYIVYKDLKERGYYVQPSAADFRVYPRGSHPGKSAAKIFVHVLSERQPLPVKLLQDSVISAENVHKQFILAVVDEESDLTFYEIKTASPQGEMPEPYPEVKTDATFLEDRVIAWDAEASGALYAGGFYGKMLDPERLQLSLVESLYLFSRGIIVVRDRKDRIFSFDEFVEKASEIESSFLRKYGAYKALRDSGHVVKTGFKFGTHFRVYRKVESIEKIPHSEYLVNVIPSDYEFRLPVMSGAVRLANSVRKRMLFAVEKEEGVEYLDISRVKM
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal long subfamily.
Protein: DER_BACFN
Sequence: MGNLVAIVGRPNVGKSTLFNRLTKTRQAIVNDEAGTTRDRQYGKSEWLGREFSVVDTGGWVVNSDDIFEEEIRKQVLMAVDEADVILFVVDVTNGVTDLDMQVAAILRRAKSPVIMVANKTDNHELRYNAPEFYRLGLGDPYCISAISGSGTGDLMDLIVSKFKKESDEILDEDIPRFAVVGRPNAGKSSIVNAFIGEERNIVTEIAGTTRDSIYTRYNKFGFDFYLVDTAGIRKKNKVNEDLEYYSVVRSIRAIEGADVCILMVDATRGIESQDLNIFSLIQKNSKGLVVVVNKWDLVENKTDKVMKTFEEAIRSRFAPFVDFPIVFASALTKQRILKVLEEARKVYENRMIKIPTARLNEEMLPLIEAYPPPATKGKYIKIKYVTQLPNTQVPSFVFFANLPQYVKEPYRRFLENKMREKWDLSGTPINIYIRQK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: OLEO2_SOYBN
Sequence: MTTVPPHSVQVHTTTHRYEAGVVPPARFEAPRYEAGIKAPSSIYHSERGPTTSQVLAVVAGLPVGGILLLLAGLTLAGTLTGLVVATPLFIIFSPVLIPATVAIGLAVAGFLTSGVFGLTALSSFSWILNYIRETQPASENLAAAAKHHLAEAAEYVGQKTKEVGQKTKEVGQDIQSKAQDTREAAARDARDAREAAARDARDAKVEARDVKRTTVTATTATA
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
What are the official names of this protein?
P24 oleosin isoform B, P91.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Protein: SPRTN_XENTR
Sequence: MQLSVVDPTWELLDPNPDIRALFLEFNDTFFWGQLSGIEVKWSARMTLCAGVCSYEGRGGLCSIRLSEPLLKLRPRKDLVQTLLHEMIHALLFVTHNNKDHDSHGPEFCKHMERINKRTGANISVYHNFHDEVDEYRKHWWLCNGPCQKRKPYFGYVKRAMNRAPSSLDPWWADHQRTCGGEFVKIKEPENYSQKRKRNNDPTKSELGNSSHVKINKGKSNGVDIRTVIPFSGTGYKLFEPSKSDAQLKIQNDNPTKDKAVMHHTPPSTNQTDSTFLSRKIVSAKKISVANTKVFINLNGSPIKLPSSSNNKSHQDSSKQKSVLHFFKTQKDNSIDLTSSSQSFPSTSQGPNREETEHFYKKLQMDDKESKDTFIIHSLNKTNVSDSLNNKSCAGPAATINSGLNHTKVCCPVCGTEIFESKINDHLDTCLQNYNT
What is the function of this protein?
DNA-dependent metalloendopeptidase that mediates the proteolytic cleavage of covalent DNA-protein cross-links (DPCs) during DNA synthesis, thereby playing a key role in maintaining genomic integrity (By similarity).  DPCs are highly toxic DNA lesions that interfere with essential chromatin transactions, such as replication and transcription, and which are induced by reactive agents, such as UV light or formaldehyde.  Associates with the DNA replication machinery and specifically removes DPCs during DNA synthesis.  Acts as a pleiotropic protease for DNA-binding proteins cross-linked with DNA, such as top1, top2a, histones H3 and H4 (By similarity).  Mediates degradation of DPCs that are not ubiquitinated, while it is not able to degrade ubiquitinated DPCs.  SPRTN activation requires polymerase collision with DPCs followed by helicase bypass of DPCs (By similarity).  May also act as a 'reader' of ubiquitinated pcna: facilitates chromatin association of rad18 and is required for efficient pcna monoubiquitination, promoting a feed-forward loop to enhance pcna ubiquitination and translesion DNA synthesis.  Acts as a regulator of translesion DNA synthesis by recruiting vcp/p97 to sites of DNA damage (By similarity).
What are the official names of this protein?
DNA-dependent metalloprotease SPRTN, Protein with SprT-like domain at the N terminus, Spartan.
What is the protein family that this protein belongs to?
Belongs to the Spartan family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of UV damage via the PIP-box. Recruited to stalled replication forks at sites of replication stress.
Protein: SYR_CHLTE
Sequence: MRAFFLPFIQDALQKAGIETDKEIQIDKPNDKKFGDFSTNIAFLVAKEARKNPRELAGQLIGLLDFPEGTVTKTEVAGPGFINFHLAPAFFMRSAQEVLAKGEGFGCNESGKGLKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQGYEVTREYYFNDAGRQMQILAESVRYRYLEKCGQVIEFPETHYQGDYIGEIAETLFIEHGDGLAATDELTIFKEAAEAVIFSSIRKTLERLLITHDSFFNEHTLYQSREGQPSANQRVIDALDAKGFIGNYDGATWFMTTKLGQEKDKVLIKSSGDPSYRLPDIAYHVTKFERGFDLMVNVFGADHIDEYPDVLEALKILGYDTSKVKIAINQFVTTTVGGQTVKMSTRKGNADLLDDLIDDVGADATRLFFIMRGKDSHLNFDVELAKKQSKDNPVFYLQYAHARICSLVRMAEKEVGFDEATAIGAGLPLLSSEPEIDLASALLDFPDIIQSSLRQLEPQKMVEYLHTVAERYHKFYQECPILKADEHLRTARLELSLAVRQVLRNGFKILGISAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_NITEU
Sequence: MLADLSEALRERQQEGLYRSRPVLEGPQSPHVTIDGRDFLAFCSNDYLGLANHPALIEAAAEGARCYGVGSGASHLISGHFRAHHELEEALAAFVGLPRTLLFSTGYMANMAVVTALAGRGDAIFADRLNHASLNDAALLSRARFIRYPHLDLDTLARQLETTKARRRLVVTDAVFSMDGDMAPVAELLTLCQRFDAWLLLDDAHGFGVLGERGKGSLYHSQRIERDTPYLIYMATLGKAAGVSGAFVAAQAPVVETLIQHGRTYGYTTAAPPLLAHTLLTSLQLISQESWRRERLALLIERLRQRLHSLPWPLLLSETPIQPLLVGESQEAVRLDLALRERGIWVPAIRPPTVPQGMARLRISLSAVHTEADVDRLGAALRDLAQC
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: ATPD_THESQ
Sequence: MRFSAVAGRYARALLNVAIEKEKEEEYLRFLDLVCQIYESSRELFDNPILKPEKKISLIKEIMKSFGQEMDEFQERFLTLVFERKRQKLLRNIRDLFEYEKILSEQKVPANLSIAHSPEDEELSLLRKFVRKYALKDPVFDISIDESLIAGALVEFEGFRLDTTVQGRLKRIAREALKRGEMS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SHDAG_HDVS2
Sequence: MSQSETRRGRRGTREETLEKWITARKKAEELEKDLRKARKTIKKLEEENPWLGNILGIIRKGKDGEGAPPAKRPRTDQMEVDSGPGKRPHKSGFTDKEREDHRRRKALENKKKQLSAGGKILSKEEEEELRRLTDEDEERKRRVAGPRVGDVNPSRGGPRGAPGGGFVPQMAGVPESPFSRTGEGLDIRGTQGFP
What is the function of this protein?
Promotes both transcription and replication of genomic RNA.  Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA.  RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome (By similarity).
What are the official names of this protein?
Small delta antigen, S-HDAg, p24.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LIPA_CORGL
Sequence: MTIAPEGRRLLRVEARNSETPIETKPRWIRNQVKNGPEYQDMKERVAGASLHTVCQEAGCPNIHECWESREATFLIGGANCSRRCDFCMINSARPEPLDRGEPLRVAESVREMQLNYSTITGVTRDDLDDEGAWLYSEVVRKIHELNPHTGVENLVPDFSGKKDLLQEVFESRPEVFAHNVETVPRIFKRIRPAFRYERSLDVIRQARDFGLVTKSNLILGMGETKEEITEALQDLHDAGCDIITITQYLRPGPLFHPIERWVKPEEFLEHADAAKEMGFAAVMSGPLVRSSYRAGRLYAQAMEFRGEEIPAHLAHLKDTSGGSTAQEASTLLERYGASEDTPVVSFN
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_HAEIE
Sequence: MARTTPIERYRNIGISAHIDAGKTTTTERILFYTGVSHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMSQQFPQHRINVIDTPGHVDFTVEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYEVPRIAFVNKMDRTGANFLRVVEQLKTRLGANAIPLQLPVGAEENFTGVVDLIKMKAINWNEADQGMTFTYEEVPANMQADCEEWRQNLVEAAAEASEELMEKYLGGEDLTEEEIKSALRQRVLANEIILVTCGSAFKNKGVQAMLDAVVEYLPAPTDIPAIKGINPDETEGERHASDEEPFSSLAFKIATDPFVGNLTFFRVYSGVINSGDTVLNSVRQKRERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCAIDAPIILERMEFPEPVISVAVEPKTKADQEKMGLALGRLAQEDPSFRVHTDEESGETIISGMGELHLDIIVDRMKREFKVEANIGKPQVSYRETIRTRVNDVEGKHAKQSGGRGQYGHVVIDLYPLDPEGPGYEFVNEIKGGVIPGEYIPAVDKGIQEQLKSGPLAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASLAFKAAFSKANPVLLEPIMKVEVETPPEYVGDVIGDLSRRRAMVNGQEANEFVVKIDAEVPLSEMFGYATDLRSQTQGRASYSMEPLKYAEAPTSVAAAVIEARKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO1_CALBD
Sequence: MKLVIFDGNSILYRAFFALPELTTSNNIPTNAIYGFVNVILKYLEQEKPDYVAVAFDKRGREARKSEYEEYKANRKPMPDNLQVQIPYVREILYAFNIPIIEFEGYEADDVIGSLVNQFKNTGLDIVIITGDRDTLQLLDKNVVVKIVSTKFDKTVEDLYTVENVKEKYGVWANQVPDYKALVGDQSDNIPGVKGIGEKSAQKLLEEYSSLEEIYQNLDKIKSSIREKLEAGKDMAFLSKRLATIVCDLPLNVKLEDLRTKEWNKERLYEILVQLEFKSIIKRLGLSEVVQFEFVQQRTDIPDVEQKELESISQIRSKEIPLMFVQGEKCFYLYDQESNTVFITSNKLLIEEILKSDTVKIMYDLKNIFHQLNLEDTNNIKNCEDVMIASYVLDSTRSSYELETLFVSYLNTDIEAVKKDKKIVSVVLLKRLWDELLRLIDLNSCQFLYENIERPLIPVLYEMEKTGFKVDRDALIQYTKEIENKILKLETQIYQIAGEWFNINSPKQLSYILFEKLKLPVIKKTKTGYSTDAEVLEELFDKHEIVPLILDYRMYTKILTTYCQGLLQAINPSSGRVHTTFIQTGTATGRLASSDPNLQNIPVKYDEGKLIRKVFVPEGGHVLIDADYSQIELRILAHISEDERLISAFKNNVDIHSQTAAEVFGVDIADVTPEMRSQAKAVNFGIVYGISDYGLARDIKISRKEAAEFINKYFERYPKVKEYLDNTVKFARDNGFVLTLFNRKRYIKDIKSTNRNLRGYAERIAMNSPIQGSAADIMKLAMIKVYQKLKENNLKSKIILQVHDELLIEAPYEEKDIVKEIVKREMENAVALKVPLVVEVKEGLNWYETK
What is the function of this protein?
In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity.
What are the official names of this protein?
DNA polymerase I, Pol I.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
Protein: ATPG_SHEHH
Sequence: MANAKEIKTKIASVKNTQKITSAMEMVAASKMRRAQDRMAASRPYAENMRKVIGHVAQGSLEYKHPYLEVREAKRVGYIVVSTDRGLCGGLNVNLFKKVIADVKKQREAGAEVEFCTIGARSAQFFNSFGGQVSASASGLGDAPKLVDLIGTVRVMLEAYNEGKLDRLYVVFNKFVNTMAQTPVIEQLLPLPKSEEGEFTHQWDYIYEPDPKLLLDTLLVRFVESQVYQGVVENIASEQAARMVAMKAATDNAGELIDDLQLVYNKARQAAITQELSEIVAGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTMR7_PONAB
Sequence: MEHIRTPKVENVRLVDRVSPKKAALGTLYLTATHVIFVENSPGSRKETWILHSQISTIEKQATTATGCPLLIRCKNFQIIQLIIPQERDCHDVYISLIRLARPVKYGELYCFSFNPMLDKEEREQGWVLIDLSEEYKRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWLRHIKAIMDAGIFIAKAVSEEGTSVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLIEKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHHIYSCQFGNFLCNSQKERQELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHLPTIPCNFMYKFWSGMYNRFEKGMQPRQSVTDYLMAVKEETQQLEEELEALEERLEKIQKVQLNCTKVKSKQSEPSKHSGFSTSDNSIANTPQDYSGNMKSFPSRSPSQGDEDSALILTQDNLKSSDPDLSANSDQESGVEDLSCRSPSGGEHAPSEDSGKDRDSDEAVFLTA
What is the function of this protein?
Phosphatase that specifically dephosphorylates phosphatidylinositol 3-phosphate (PtdIns(3)P) and inositol 1,3-bisphosphate (Ins(1,3)P2).
What are the official names of this protein?
Myotubularin-related protein 7, Inositol 1,3-bisphosphate phosphatase, Phosphatidylinositol-3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Endomembrane system; Peripheral membrane protein; Cytoplasmic side. Note=May partially localize to endosomes and/or the Golgi apparatus.
Protein: Y06O_BPT4
Sequence: MSKPSLYLPSKPLKYELKRQIISTDVLIGPVIAISFVILLIIGGVLDVMTDIDSGVIIMLMLTLPLVVPFLLVPVNWIGYWYQGRHYRKRVRDWKAQCKKIKKEHQLKLAEYEFNEIMKFVKESRCKSQS
What are the official names of this protein?
Uncharacterized 15.1 kDa protein in e-segB intergenic region.
Protein: ZC3H3_HUMAN
Sequence: MEEKEILRRQIRLLQGLIDDYKTLHGNAPAPGTPAASGWQPPTYHSGRAFSARYPRPSRRGYSSHHGPSWRKKYSLVNRPPGPSDPPADHAVRPLHGARGGQPPVPQQHVLERQVQLSQGQNVVIKVKPPSKSGSASASGAQRGSLEEFEETPWSDQRPREGEGEPPRGQLQPSRPTRARGTCSVEDPLLVCQKEPGKPRMVKSVGSVGDSPREPRRTVSESVIAVKASFPSSALPPRTGVALGRKLGSHSVASCAPQLLGDRRVDAGHTDQPVPSGSVGGPARPASGPRQAREASLVVTCRTNKFRKNNYKWVAASSKSPRVARRALSPRVAAENVCKASAGMANKVEKPQLIADPEPKPRKPATSSKPGSAPSKYKWKASSPSASSSSSFRWQSEASSKDHASQLSPVLSRSPSGDRPAVGHSGLKPLSGETPLSAYKVKSRTKIIRRRSSTSLPGDKKSGTSPAATAKSHLSLRRRQALRGKSSPVLKKTPNKGLVQVTTHRLCRLPPSRAHLPTKEASSLHAVRTAPTSKVIKTRYRIVKKTPASPLSAPPFPLSLPSWRARRLSLSRSLVLNRLRPVASGGGKAQPGSPWWRSKGYRCIGGVLYKVSANKLSKTSGQPSDAGSRPLLRTGRLDPAGSCSRSLASRAVQRSLAIIRQARQRREKRKEYCMYYNRFGRCNRGERCPYIHDPEKVAVCTRFVRGTCKKTDGTCPFSHHVSKEKMPVCSYFLKGICSNSNCPYSHVYVSRKAEVCSDFLKGYCPLGAKCKKKHTLLCPDFARRGACPRGAQCQLLHRTQKRHSRRAATSPAPGPSDATARSRVSASHGPRKPSASQRPTRQTPSSAALTAAAVAAPPHCPGGSASPSSSKASSSSSSSSSPPASLDHEAPSLQEAALAAACSNRLCKLPSFISLQSSPSPGAQPRVRAPRAPLTKDSGKPLHIKPRL
What is the function of this protein?
Required for the export of polyadenylated mRNAs from the nucleus (PubMed:19364924).  Enhances ACVR1B-induced SMAD-dependent transcription.  Binds to single-stranded DNA but not to double-stranded DNA in vitro.  Involved in RNA cleavage (By similarity).
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 3, Smad-interacting CPSF-like factor.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_SALPK
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DEAD_MYCTO
Sequence: MAFPEYSPAASAATFADLQIHPRVLRAIGDVGYESPTAIQAATIPALMAGSDVVGLAQTGTGKTAAFAIPMLSKIDITSKVPQALVLVPTRELALQVAEAFGRYGAYLSQLNVLPIYGGSSYAVQLAGLRRGAQVVVGTPGRMIDHLERATLDLSRVDFLVLDEADEMLTMGFADDVERILSETPEYKQVALFSATMPPAIRKLSAKYLHDPFEVTCKAKTAVAENISQSYIQVARKMDALTRVLEVEPFEAMIVFVRTKQATEEIAEKLRARGFSAAAISGDVPQAQRERTITALRDGDIDILVATDVAARGLDVERISHVLNYDIPHDTESYVHRIGRTGRAGRSGAALIFVSPRELHLLKAIEKATRQTLTEAQLPTVEDVNTQRVAKFADSITNALGGPGIELFRRLVEEYEREHDVPMADIAAALAVQCRGGEAFLMAPDPPLSRRNRDQRRDRPQRPKRRPDLTTYRVAVGKRHKIGPGAIVGAIANEGGLHRSDFGQIRIGPDFSLVELPAKLPRATLKKLAQTRISGVLIDLRPYRPPDAARRHNGGKPRRKHVG
What is the function of this protein?
DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
What are the official names of this protein?
ATP-dependent RNA helicase DeaD, Cold-shock DEAD box protein A.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAF1_YEAST
Sequence: MKFIDELDIERVNQTLNFETNDCKIVGSCDIFTTKAVASDRKLYKTIDQHLDTILQENENYNATLQQQLAAPETNQSPCSSPFYSNRRDSNSFWEQKRRISFSEYNSNNNTNNSNGNSSNNNNYSGPNGSSPATFPKSAKLNDQNLKELVSNYDSGSMSSSSLDSSSKNDERIRRRSSSSISSFKSGKSSNNNYSSGTATNNVNKRRKSSINERPSNLSLGPFGPINEPSSRKIFAYLIAILNASYPDHDFSSVEPTDFVKTSLKTFISKFENTLYSLGRQPEEWVWEVINSHMTLSDCVLFQYSPSNSFLEDEPGYLWNLIGFLYNRKRKRVAYLYLICSRLNSSTGEVEDALAKKPQGKLIIDDGSNEYEGEYDFTYDENVIDDKSDQEESLQ
What is the function of this protein?
Mediator of diverse signals that repress RNA polymerase III transcription.  Inhibits the de novo assembly of TFIIIB onto DNA.
What are the official names of this protein?
Repressor of RNA polymerase III transcription MAF1.
What is the protein family that this protein belongs to?
Belongs to the MAF1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL10_NITSB
Sequence: MTRSQKEEVVQYLTEEFKNAAAIVDCDYKGMSVSELESLRRIAKEKGLKVRVVKNTLAMIALRNNGVEDFQLKDTNVLIWGDDLVELAKTVTDFAKEHKENFQIKQGYFEGEVADASKIEAYSKLPSKEELLGMLLSVWTAPIRNLLYVWNAPKQNFVTVLENIRQQKES
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.