PharMolix/UniProtQA huggingface dataset:
Protein: MMM12_YARLI
Sequence: MVIPAELIQKALKQQSGWGFTEGLVLGQLSVIITVIIILKFVIFAENKSPKKGNDMTAVSAKDKEAEHVAMGGQTANGVKTSGVRRNKSSTNLRNRLATGAAGASISRPGSSRVSMVRSTSGAVPVLGQNGGATPRGMAGSSVAGSTSNLAVPVPTTPTIAEGIEPENDSTLQDDSAIIDLDLDLDLSPVDEILHKTCYQLSSHAPESLDWFNVLVAQIITQLRFDAKANNNLNLLNSLDAAFNSKRPDFIDRINVTEINLGDDYPILSNCKITHKGTGPAGSGAASGNNMPNNAEYDDSRLEAQMDIDLSDTITLGIETRLNLNQPKILSPFLSLSTSLPVSLSVTIVRFTARLNISLYQQIEQTEEDEKDKRDTILSINFEPDYKLQLSVKSLVGSRSRLQNVPTLESLVDSKIQKWFRDHYVEPHQMIFILPSLWPRKKRSATAGAAGTATGADTASGSS
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Maintenance of mitochondrial morphology protein 1-2.
What is the protein family that this protein belongs to?
Belongs to the MMM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: THUM2_HUMAN
Sequence: MSEARGEPGSGPEAGARFFCTAGRGLEPFVMREVRARLAATQVEYISGKVFFTTCSDLNMLKKLKSAERLFLLIKKQFPLIISSVSKGKIFNEMQRLINEDPGSWLNAISIWKNLLELDAKKEKLSQRDDNQLKRKVGENEIIAKKLKIEQMQKIEENRDCQLEKQIKEETLEQRDFTTKSEKFQEEEFQNDIEKAIDTHNQNDLTFRVSCRCSGTIGKAFTAQEVGKVIGIAIMKHFGWKADLRNPQLEIFIHLNDIYSVVGIPVFRVSLASRAYIKTAGLRSTIAWAMASLADIKAGAFVLDPMCGLGTILLEAAKEWPDVYYVGADVSDSQLLGTWDNLKAAGLEDKIELLKISVIELPLPSESVDIIISDIPFGKKFKLGKDIKSILQEMERVLHVGGTIVLLLSEDHHRRLTDCKESNIPFNSKDSHTDEPGIKKCLNPEEKTGAFKTASTSFEASNHKFLDRMSPFGSLVPVECYKVSLGKTDAFICKYKKSHSSGL
What are the official names of this protein?
THUMP domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: Y738_ARCFU
Sequence: MHKEEIILLHLTLYNIKKLFENAGIANGHFKAYDELGVQPVHIHKSKTEHKKAISLLCKGISEIFRERSPEDLIESENLKFVIESIAPELCEP
What are the official names of this protein?
UPF0058 protein AF_0738.
What is the protein family that this protein belongs to?
Belongs to the UPF0058 family.
Protein: RL2_RHIWR
Sequence: MALKHYNPTSPARRGLILVDKSGLHKGKPVKALTEGKRKSGGRNNQGHATARGIAGGHKQKYRIVDFKRRKWDQPATVERLEYDPNRSAFIALVKYEDGELAYILAPQRLAAGDVVLAAKKTDTKPGNAMEIGQAPVGTIVHNVEMKPGKGGQIARAAGTYVQIVGRDKGMVMVRLNSGEQRYIRSDCMCTVGAVSNPDNANQNLAKAGRNRWLGRRPLTRGVAKNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGARTRHNKATDKFIIRSRHAKKKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: GLNE_BRASO
Sequence: MTSSAPGNADGQSRLAARFVAGPHVRAPDTAEHRLQDWLAELEPSLAASLRDQFASGWARSILLGIVESSPYLFDLIRADAQRLDRLLRCDPQTHLAELIARTGREVFACSGEADVMSLLRRLKSEAALLIALCDIGGVWPVMQVTAALTDVAVAAVQMALRHLLRQEAARGRLAPIDPAQPELGCGLFVLAMGKMGAGELNYSSDIDLIVFFDPDATTLAHDIEPQPFFVRVTQALARLLQSRTADGYVFRVDLRLRPDPASTQVAMSTEAALHYYEREGRTWERAAMIKARICAGDVAAGEAMLAELSPFVWRKHLDFQALTDVHDMKRQMQVYRGHSEIAVEGHNVKVGRGGIREIEFFAQTQQLIAGGRHPELRVRPTLQALDVLTASNWITAQARDELTSAYEFLRRVEHRLQMMADEQIHSLPDDVDGVARFACFFGYESRERFATDLLFHLDIVQGHYARLFEGDPTGTVSLPPVNYGAGPDEPRLLEHLVALGFRDPMMVALTLQQWLAGDYRVFRAEATRTTFNEFLPALIDGLAHADEPDRAVVAFDRFLQALQLGGRLITLLGQNRDLVALVALVLGAAPRLGDMLARQPRLMDGLIDPRFFGAIPDKRELSTRLAATLQDAGSYEEFLDRLRLFGQESLFLIGTRILSGTVSAQQAGTAFADVAEGIVHTVHNLVIERFAAQHGRIRGQETAIIAMGRLGAREMTASSDLDLILLYDFDADAPDSDGERPLQGAHYFARFTQRLISAFTSRTNYGVLYDIDMRLRPSGRAGPLASHIDSFAHYQEHEAWTWEHMALTRARVISASPAFRARIEAIIQTALRRSRDAQAIARDVADMRRAIAAEKGETDLWDLKHAAGGMVDIDFVAQYLQLVHAASKPEILDISSLQVLDHAERLGVLPRADAVILRHAARMYHDLTQILRLCVSDKFKPDQAGDDLLRVMTRAGDAPDFSALEARVRETQSEVRRVFTALLER
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: NDHJ_PLAOC
Sequence: MQGRLSAWLVKHGLVHRSLGFDYQGIETLQIKSEDWHSIAVISYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIQYGVDQPEEVCIKVFAARRNPRIPSVFWIWKSADFQERESYDMLGISYDNHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: CTSL2_HUMAN
Sequence: MRLRTRKASQQSNQIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEERENPSKRSRIERDIDNNLITSTPRAGEKPNKQISRVRRKSQVNGEAGSYEMTNQHVKQNGKLEDNPSSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTTTSTNGAAYSNQAVQVRPSLNNGLEEAEETVNRDIPPLTAPVTPDSGYSSAHAEATYEEDWEVFDPYYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVIYQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGNYIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDVRPHIRDRFRLHDLLPPD
What is the function of this protein?
Probable phosphatase.
What are the official names of this protein?
CTD small phosphatase-like protein 2, CTDSP-like 2.
What is the protein family that this protein belongs to?
Belongs to the CTDSPL2 family.
Protein: MA7D1_HUMAN
Sequence: MESGPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFSTNGPSGDKSLSRTPETLLPFAEAEAFLKKAVVQSPQVTEVL
What are the official names of this protein?
MAP7 domain-containing protein 1, Arginine/proline-rich coiled-coil domain-containing protein 1, Proline/arginine-rich coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the MAP7 family.
Protein: PURA_SHIFL
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPAELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACB2_DANRE
Sequence: MSAVIPRIEQLSARVVRVLGCNPGPMTLQGTNTYLVGTGRRRVLIDAGERAVPEYIVSLREALKQHDTSIQHIIVTHWHHDHTGGVQDILAHFNTDAELRVSKLPRCPPQEEIIGDDKKKYSYLNDGDVIQTEGATLRVLFTPGHTDDHMALLLEEEQAVFSGDCILGEGTAVFEDLHDYMKSLQKLLSIKADLIYPGHGPVVHDAGSKIHEYIIHRNAREQQILNVLLENSGTAFTSSELVKVVYKETPEHLHRAAEFNLLHHLRKLLKDGKICLAEGSDEKKWKSNL
What is the function of this protein?
Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA.  The cleavage product contains a free 3' -OH group.  Has no activity with double-stranded RNA or DNA.  Required for normal mitochondrial function and cell viability.
What are the official names of this protein?
Endoribonuclease LACTB2, Beta-lactamase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PO6F1_HUMAN
Sequence: MPGISSQILTNAQGQVIGTLPWVVNSASVAAPAPAQSLQVQAVTPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTVPQPAVVIASPAPAAKPSASAPIPITCSETPTVSQLVSKPHTPSLDEDGINLEEIREFAKNFKIRRLSLGLTQTQVGQALTATEGPAYSQSAICRFEKLDITPKSAQKLKPVLEKWLNEAELRNQEGQQNLMEFVGGEPSKKRKRRTSFTPQAIEALNAYFEKNPLPTGQEITEIAKELNYDREVVRVWFCNRRQTLKNTSKLNVFQIP
What is the function of this protein?
Transcription factor that binds preferentially to a variant of the octamer motif (5'-ATGATAAT-3').
What are the official names of this protein?
POU domain, class 6, transcription factor 1, Brain-specific homeobox/POU domain protein 5, Brain-5, Brn-5, mPOU homeobox protein.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-6 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHH_MACLE
Sequence: MIRSSVMGPTMFLVVLLLIASHQTSAWSLDGLARIEKLLSTSSSASAASPTRGQALNLKKRAILDQSCKGIFDRELFKKLDRVCDDCYNLYRKPYVAIDCREGCYQNLVFRQCIQDLQLMDQLDEYANAVQIVGK
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction (By similarity).
What are the official names of this protein?
Crustacean hyperglycemic hormones.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCOA_MYCTU
Sequence: MDKVVATAAEAVADIANGSSLAVGGFGLCGIPEALIAALVDSGVTDLETVSNNCGIDGVGLGLLLQHKRIRRTVSSYVGENKEFARQFLAGELEVELTPQGTLAERLRAGGMGIPAFYTPAGVGTQVADGGLPWRYDASGGVAVVSPAKETREFDGVTYVLERGIRTDFALVHAWQGDRHGNLMYRHAAANFNPECASAGRITIAEVEHLVEPGEIDPATVHTPGVFVHRVVHVPNPAKKIERETVRQ
What are the official names of this protein?
Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit A, Succinyl-CoA:3-oxoacid CoA-transferase, OXCT A.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit A family.
Protein: SYFA_MALP2
Sequence: MTKIDFENIKILQDKIKDIEIEKNVYDERNIFLKNYLSPLYKELKEMSEEDKKEFGKQLNQYKEMIEDVAEKRINEIKKQKILNIKSEYDINLPADYFQSGGINPIDLVKNEIVKFFKKANFKILTESEVTSVEFNFDSLNIKKDHPARSISDTFYIDDKQLLRVHNTAITSKALRMFNKEEEIKVLSHGNVYRKDDDDATHSHQFNQIDMVWVKKGMSLANLKWLTDKLLKYLFNESIKIRYRISHFPFTEPSFEVDINCFFCDSKDHCSVCKNTKWIEVLGAGLLHPNVLKNANVKKGLSGIAFGIGIDRIAMLKYQIKDIRRLYGNDFSLIESFKGER
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_POMRU
Sequence: FGLLLGICLIVQIVTGLLLAAHYTADTSLAFASVAHMCRNVQFGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLNKETWNIGVILLLTLMATAFVGYVXPWGQMSYWGATVITNLFSAIPYIGQTLVEWDWGGFSVDNPTLTRFFALHFLLPFVFAGLTLVHLTFLHETGSNKPLGIPSDCDKIPFHPYYSTKDVLGFVLMLIPLITLALFSPNLLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLVLFLIPFLHTSKLRSMTFRPLSQILFWTLVANLLMLTWVSN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TBCE_MOUSE
Sequence: MSDILPLDVIGRRVEVNGEYATVRFCGAVPPVAGLWLGVEWDNPERGKHDGSHEGTMYFKCRHPTGGSFVRPSKVNFGDDFLTALKKRYVLEDGPDDDENSCSLKVGSKQVQTIGFEHITKKQSQLRALQDISLWNCAVSHAGEQGRIAEACPNIRVVNLSKNLLSTWDEVVLIAEQLKDLEALDLSENKLQFPSDSPTLTRTFSTLKTLVLNKTGITWTEVLHCAPSWPVLEELYLKSNNISISERPVNVLQKMRLLDLSSNPSIDESQLSLIADLPRLEHLVLSDIGLSSIHFPDAEIGCKTSMFPALKYLIVNDNQISEWSFINELDKLQSLQALSCTRNPLSKADKAEEIIIAKIAQLRTLNRCQILPEERRGAELDYRKAFGNEWRKAGGHPDPDKNRPNAAFLSAHPRYQLLCCKYGAPEDEELKTQQPFMLKKQLLTLKIKCSNQPERQILEKQLPDSMTVQKVKGLLSRLLKVPVSELLLSYESSKMPGREIELENDLQPLQFYSVENGDCLLVRW
What is the function of this protein?
Tubulin-folding protein; involved in the second step of the tubulin folding pathway and in the regulation of tubulin heterodimer dissociation (PubMed:12389029, PubMed:17184771).  Required for correct organization of microtubule cytoskeleton and mitotic splindle, and maintenance of the neuronal microtubule network (By similarity).
What are the official names of this protein?
Tubulin-specific chaperone E, Tubulin-folding cofactor E.
What is the protein family that this protein belongs to?
Belongs to the TBCE family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: NRDR_MYCTU
Sequence: MHCPFCRHPDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSREKVISGVRRACQGRQVDDDALNLLAQQVEDSVRAAGSPEIPSHDVGLAILGPLRELDEVAYLRFASVYRSFSSADDFAREIEALRAHRNLSAHS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RL18_BORPE
Sequence: MDKKVSRLRRAVPTRRKIAQLRVHRLSVFRSNLHIYANIISPEGDRVLVSASTLEAEVRAQLGGAGKGGNATAAALVGKRVAEKAKAAGIELVAFDRSGFRYHGRVKALAEAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RA51C_ARATH
Sequence: MISFGRRKSPAIEETSLATSVMEAWRLPLSPSIRGKLISAGYTCLSSIASVSSSDLARDANITEEEAFEILKLANQSCCNGSRSLINGAKNAWDMLHEEESLPRITTSCSDLDNILGGGISCRDVTEIGGVPGIGKTQIGIQLSVNVQIPRECGGLGGKAIYIDTEGSFMVERALQIAEACVEDMEEYTGYMHKHFQANQVQMKPEDILENIFYFRVCSYTEQIALVNHLEKFISENKDVKVVIVDSITFHFRQDYDDLAQRTRVLSEMALKFMKLAKKFSLAVVLLNQVTTKFSEGSFQLALALGDSWSHSCTNRVILYWNGDERYAYIDKSPSLPSASASYTVTSRGLRNSSSSSKRVKMM
What is the function of this protein?
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
What are the official names of this protein?
DNA repair protein RAD51 homolog 3, DNA repair-recombination protein RAD51C, AtRAD51C.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RAD51 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KAD6_THEON
Sequence: MIISVSGTPGAGKTTVSKLLSERLGYEYVSVKELALSRGIGERVSDEIEIDVDELARVVREEFSGRNVVLDGHLSHFVPADVVIILRAHPRLIAERLKARGYSKKKLAENVEAELVDVILVEALEENERVLEVDTTGKSPEEVVEEILTLLKSGTKKRVGIVDWSEEYDKVVQYLMLGDD
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.
What are the official names of this protein?
Putative adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
Protein: EUTC_ECOL6
Sequence: MDQKQIEEIVRSVMASMGQTAPAPSEAKCATTNCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: HCR_ECOLI
Sequence: MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYALVSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSQWLTRDVKRGDYLWLSDAMGEFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVRVIYNVRTPQDVIFADEWRNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALGVTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAGVCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVLA
What is the function of this protein?
NADH oxidoreductase acting in concert with HCP.
What are the official names of this protein?
NADH oxidoreductase HCR.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FAD-binding oxidoreductase type 6 family.
Protein: EX7S_BURP0
Sequence: MAKTATPGACASDPGSGPLPENYEMALAELEALVARMEGGTLSLEDSLAAYRRGAALVAFCQQQLEKAEQQVRVLDGASLKPLSAGTAAADGEDDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_VIBPA
Sequence: MTIKILPARLANQIAAGEVVERPASVIKELVENSLDSGATRIDIDIEKGGAKLIRVRDNGKGIAKDELGLALSRHATSKIHTLDDLEAIMSLGFRGEALASISSVSRLTLTSRPAAQEEAWSAYSEGRDMQVKLQPAAHPIGTTVEVLDLFFNTPARRKFLRTEKTEFAHIDELLKRIALSRFDVSINVRHNGKVIRQYRAAKNQLQTEKRIAAVCGNAFVRNMLRIELEHQGLKLHGWITTPDGARQQSDLQYCYVNGRMMRDKLINHAIRQSYEMSLKPDQFAAYVLFIELDPHQVDVNVHPAKHEVRFHQARLVHDFIYQALADALAQSSVIDKPQVNESAFHRAEPEERESQPETTPQYSPQSVSTTVPERVYQAIDKTPTYPGRTDYEIKPRDRAPSDSSVREARIADSFKRTDWIESKLAPKPNVGKERHAEPAPSKREVHAYHELLKTPDFESQQAEQPTSIESVREVSLPQVTALGKALVVVDEQFVLMSSDSGVALVSLPRSEFYRTKGQLTPSEGALKAQPLLVPLSMKLDTDLVRLAQDYQQDFAQLGIQLKARNDKALMVMGVPAPLRQQNLQNLVPDLLSYAQTWMKGEKASTQMLPALIDWLAVQVTTVKSHYTLSEAIQIIAELEQLRHGQLPLDDKTFVSAVDFSATIAKLKP
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DDL_SYNJA
Sequence: MNIVILAGGRSAERQVSLVTGKACKRALEDLGHRAKLIDPEEDLPLRLWQERQAGCDFVWIALHGPGGEDGVVQGMLEWLGLPYQGSGPLASALAMDKLVSKQIFRAEGIPTPEWLVWDEAQPLSWAECVARLGSPLVVKPSNSGSTVGISLARDEVSLAQGLALASSVSSRVFLERYIPGKEITLSILSGQVLPAIEIIPAQGDFYDYEAKYAPGGSRHLIPCSLSAAGLARCEAAGLRAYRVLGCEGLARVDLRVDADENPWVLEVNTLPGMTPTSLCPEAAAALGWTFTELVERMLQDALQRAALTRSAPSGSRPSPQPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSRC_YERPA
Sequence: MLKFIQNNREGTALLAILTLFALLGIIDRNYFSLQTFTMIFSSAQILILLAIGATLVMLTRNIDVSVGSITGLCAVTVGMALNAGFGLAASCLFALLVGMVAGFFNGILVTWLRIPAIVATLGTLGLYRGLMLLLTGGKWIEGLPADLKSLSTPILFSISPIGWLTMLLILAMAWLLGKTAFGRSFYATGDNLQGARQLGVRTDSLRIFAFSMNGVMAALAGIVFASQIGFIPNQTGNGLEMKAIAACVLGGISLLGGTGTIIGAILGAFLLTQIDSVLVLLRLPAWWNDFIAGLVLLGVLVFDGRLRCAVERNIRQQKYARFTAQAIISDKKPTVSDNNPAASNKKKAAL
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Autoinducer 2 import system permease protein LsrC, AI-2 import system permease protein LsrC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HUTI_STRPQ
Sequence: MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYLFYFFATNLIHQVYKKGQLTVDRGRIL
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.