PharMolix/UniProtQA huggingface dataset:
Protein: SYY_ECO81
Sequence: MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTADSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFTFMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEDGLQAAKRITECLFSGSLSALSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQSDPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCP_IRV1
Sequence: MSMSSSNITSGFIDIATFDEIEKYMYGGPTATAYFVREIRKSTWFTQVPVPLSRNTGNAAFGQEWSVSISRAGDYLLQTWLRVNIPPVTLSGLLGNTYSLRWTKNLMHNLIREATITFNDLVAARFDNYHLDFWSAFTVPASKRNGYDNMIGNVSSLINPVAPGGTLGSVGGINLNLPLPFFFSRDTGVALPTAALPYNEMQINFNFRDWHELLILTNSALVPPASPYVPIVVGTHISAAPVLGPVQVWANYAIVSNEERRRMGCAIRDILIEQVQTAPRQNYVPLTNASPTFDIRFSHAIKALFFAVRNKTSAAEWSNYATSSPVVTGATVNYEPTGSFDPIANTTLIYENTNRLGAMGSDYFSLINPFYHAPTIPSFIGYHLYSYSLHFYDLDPMGSTNYGKLTNVSVVPQASPAAIAAAGGTGGQAGSDYPQNYEFVILAVNNNIVRISGGETPQNYIAVC
What is the function of this protein?
Major capsid protein that self assembles to form an icosahedral capsid.  Represents around 50% of the total virion protein mass (By similarity).
What are the official names of this protein?
Major capsid protein, MCP, P50.
What is the protein family that this protein belongs to?
Belongs to the NCLDV major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CLH1_CITUN
Sequence: MAAMVDSKPAASVQGTPLLATATLPVFTRGIYSTKRITLETSSPSSPPPPKPLIIVTPAEKGTFNVILFLHGTSLSNKSYSKIFDHIASHGFIVVAPQLYTSIPPPSATNELNSAAEVAEWLPQGLQQNLPENTEANVSLVAVMGHSRGGQTAFALSLRYGFGAVIGLDPVAGTSKTTGLDPSILSFDSFDFSIPVTVIGTGLGGVARCITACAPEGANHEEFFNRCKNSSRAHFVATDYGHMDILDDNPSDVKSWALSKYFCKNGNESRDPMRRCVSGIVVAFLKDFFDGDAEDFRQILKDPSFAPIKLDSVEYIDASSMLTTTHVKV
What is the function of this protein?
Catalyzes the hydrolysis of ester bond in chlorophyll to yield chlorophyllide and phytol.
What are the official names of this protein?
Chlorophyllase-1, chloroplastic, Chlorophyll-chlorophyllido hydrolase 1, Chlase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PALF_ASHGO
Sequence: MHMRLFSKFKLHGSSAASEEVFGGKFSYTSAVADFYIELGDAHKIWKPRDVVTGEVVLTLRKPLRGVSLRMSLEGNLRVQTGSGATSRLKFQRTLFSKSSMIYGVEQPEDAEQEGHGLTRGDHRFPFRMRVPSKNIYTSIAFEKGSISYAVGCVLETRSGAQRLSSCSRQISVLVPVDVSLLPKLRPKTVVLQSPQLLRSAKANYPEHDTASSLTKRTTASANSNSSVTTVCSSKTVTISVDLPESGYVIGDTIRIKVHIQHYKEYRNSAGLIATLVRICRVHSTGTDDPMETFRKDICQCVAPLYVEPETHTCSVGMNLNVPLDAFPTLVVPNQGFTFQYYIEVLANLSSKNIVYTESNRVIGGSGMADIPMPGSKLHPVKKISMLPLKLQGPLGKQDTNIDESLIFFQDMVNVDKLKRLRNVTGTSIEVVIGTHRNNSVQQARQSCPGSPVGGSDSTMMSEQSAAGTSLPSSVLDIYDQLANRLSSSVGDQLLRYGMSPDSGPHSANDELPRYTPNVDYMVTEDKRELEQRKLKELESEPSVEEEQ
What is the function of this protein?
Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH.
What are the official names of this protein?
pH-response regulator protein palF/RIM8.
What is the protein family that this protein belongs to?
Belongs to the arrestin family. PalF/RIM8 subfamily.
Protein: AROD_STRP7
Sequence: MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: PEAK1_HUMAN
Sequence: MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGNFRPPVAKKPTIAVKPTMIVADGQSICGELSIQEHCENKPVIIGWNRNRAALSQKPLNNNNEDDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRINDCYKRSLERKLPPSCMIGGIKETQGKHVILSGSTEVISNEGGRFCYPEFSSGEESEEDVLFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKSLQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRSETASSLSQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALRLEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQPLCKPYTVVDVSAAMASEHLEGPVNSPKTKSSSSTPNSPVTSSSLTPGQISAHFQKSSAIRYQEVWTSSTSPRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTTSVISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNNCLNRGQSSPQRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSSTREKASTVLSQIVASIQPPQSPPETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTTKVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPTRSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEEDDKEKEREKGKLVGLDGTVIHMLPPPPVQRHHWFTEAKGESSEKPAIVFMYRCDPAQGQLSVDQSKARTDQAAVMEKGRAENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTALSLPELEREDGKEDISDPMDPNPCSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKTDQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMESSLCVMANPTYDIDPNWDASSAGSSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGPSCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQYYHSLAVRQSLAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEAASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVHYQPGGTAQGFGPAEPSPTSSYPTRLIVSNFSQAKQKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREYTRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTACPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIVKILQHR
What is the function of this protein?
Probable catalytically inactive kinase.  Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:23105102, PubMed:20534451, PubMed:35687021).  Acts as a scaffold for mediating EGFR signaling (PubMed:23846654).
What are the official names of this protein?
Inactive tyrosine-protein kinase PEAK1, Pseudopodium-enriched atypical kinase 1, Sugen kinase 269, Tyrosine-protein kinase SgK269.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Note=Colocalizes with F-actin in serum- rich medium (PubMed:20534451). Actin colocalization is reduced during serum starvation (PubMed:20534451).
Protein: SLU7_CRYNB
Sequence: MLSTSTSLQGGKVSREEYRRQKDLEAARKAGTAPAALDEQGNAINPHIPEYITKAPWYADTGRPSLAHQRINEQGPHLKLDEWYDRGAKAGPAAKKYRKGACENCGAMTHKMKDCVERPRKRGAKFTNKDIAPDELVQQFEGDYDAKRDRWNGYDPASYKHVVEEYEATEQMRKKYREEEIDQQTSTDMAVVKKLAKKDKEGKVEDDDDDFGSSDEDEDDEDKYADAADQVGQKLDTKTRITVRNLRIREDTAKYLINLDESSAYYDPKTRSMRDAPVRNMNPEDMKFAGDNFQRYSGDATNMQKLQLFAWQSAQKGSNINVSANPTAGELLHREFQQKKEVLKDTNKTSILAKYGGEEHLQRMPNELLSGQTENYVEYSRSGQIIKGRERAKARSKYDEDVYINNHTAIWGSYYDLSTSQWGFACCHSVLPGSYCTGDAGKLANAASSASALLASSNERSKIEEAAEKERESLAEQHLKDLASGKAKKGKEREWDLPQYAKRREDGEELDLDKGRLKNALKEEKKRKKMGEDEAWQQTKKGKTDVTQEELEAYRLSRQAYDDPMSNYQDPEDQ
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTH_POLSJ
Sequence: MIKLFVGLGNPGAEYEATRHNAGFWWIDALSRELQAPLTLDKSYHGQVARTTLNGKTVWLLKPLTFMNVSGKSVAALARFFKIAPDEVLVAHDELDIVPGQVKLKFGGSHAGHNGLRDIHAQLGTDDYWRLRIGVGHPGVKAEVINWVLKKPSQEHRVAIEECIDRALKAVPALLAGEMEKATMLIHTSQPPRPKPPRRTEPED
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_STAAS
Sequence: MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAAFDNPQGSQGATELLNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQGEVGRRKLNNVTRYLAISLAFIQSIGMAFQFNNYLKGALIINQSIMSYLLIALVLTAGTAFLIWLGDQITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVLGLLVSLILLTVGAIYVLEAVRKIPIQYAKKQTAQRLGSQATYLPLKVNSAGVIPVIFAMAFFLLPRTLTLFYPDKEWAQNIANAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEKMADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQSIQIGGTSLLIVIGVAIETMKSLEAQVSQKEYKGFGGR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLAA_HELFC
Sequence: MAFQVNTNINALNAHAMGLVTQRELKESLERLSSGLRINKAADDASGMTIADSLRSQAKSLGQAIANTNDGMGIIQIADKAMDEQIKILDTIKVKATQAAQDGQNTQSRKALQADIVRLIQSLDNIGNTTSYNGQTLLSGAFSNKEFQVGAYSNETIKASIGSATSDKIGQVKITTGKNITASGEVALTFKQVDGVHDVSLESVKISTSAGTGLGVLAEVINKNSNATGVRATANVITTSDSAIKSGSLSSLTVNGIEIGNILGIKKNDSDGRLVAALNAVTAQTGVEAYTDSVGRLNLRSIDGRGINIKANSTNVDGQASALTTLNGGQDITRGSTNFGRLSLVRQDARDILVVSGANVSASAGYAAIGFAKGTTANTTVNLRDVLGEFNQAVRSASGANYNKTLASENLTLGSGVTTLRGAMVVMDIAESAQKMLDKVRSDLGSVQNQMVSTVNNITITQVNVKAAESQIRDVDFAQESANFSKNNILAQSGSYAMSQANTVQQNILRLLT
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.  Important for motility and virulence.
What are the official names of this protein?
Flagellin A.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: THIM_CLAM3
Sequence: MSAARPSAHETTGTGTASADLLLLLRERQPLVQCITNAVVTGFTANVLLALGAAPAMTDVPTEAGPFARIASGLLVNLGTPHAEQREAAVEAAHAAREAGTPWVLDPVAVGALPVRTRLAHELVALSPTVVRGNASEVIALATGGAGGRGVDATDEVEAALDAATLLARTFGTVVAISGPVDHITDGHRVVRVHTGDALLTKVTGGGCALGAVMAAFASLDPDPLRAAVAATSVYTIAAEIAAEGASGPGSFAVGLLDALDAVTPELVAQRERLA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: AZOR_DECAR
Sequence: MKILQINASARSAGANSTRLADTVTARLLARNPNAVVELRDLASHPHPVLDEPALGALFTPADQRTAEQSARVALDDALIAQVQSVDAIVLGVPMYNFGVPVQLKTWIDAIARAGVTFHYTEKGPEGLLKGKKVYVALARGGLYRDTPADSQVPYLKSVLGFLGMTDVEFIYAEGLAMGAESASKAFAEAEAQIEELIA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: Y2132_STAS1
Sequence: MKVFIILGALNAMMAVGTGAFGAHGLENKLSAKYLSVWEKATTYQMYHGLGLLAIGIISGTTSINVNWVGWLLFFGIVFFSGSLYILALTQIRIIGAITPIGGVLFIVGWLMLVIGTFKI
What are the official names of this protein?
UPF0382 membrane protein SSP2132.
What is the protein family that this protein belongs to?
Belongs to the UPF0382 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: METK_GOSHI
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPESKVACETCSKTNMVMVFGEITTKADVDYEKIVRDTCRGIGFTSDDVGLDADNCKALVNIEQQSPDIAQGVHGHLSKRPEEIGAGDQGHMFGYATDETPELMPLTHVLATRLGARLTEVRKNGTCPWLRPDGKTQVTVEYYNDKGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVANGLARRCVVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILKIVKETFDFRPGMIAINLDLKRGGNSRFLKTAAYGHFGRDDTDFTWEVVKPLKWDKVHA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_EXISA
Sequence: MGKYFGTDGVRGVANSELTAELAYRLGRAGGYVLSKHLPEGEQPKVLIGRDTRISGHMLEGALIAGLLSIGAEVMRLGVISTPGVAYLTKSLDATAGVMISASHNPVADNGIKFFGSDGFKLDDATEQEIEDILDAAEDTLPRPTGKDLGFVSDYYEGAQKYLQMLKQTVEEDFDGLHIALDCAHGATSGLAARLFADLEANVSTIGNSPNGLNINEGVGSTHPEHLAEFVREKGADMGLAFDGDGDRLIAIDENGDIVDGDKIMYICGKYLSEKGRLKDNTIVATVMSNLGFHKAVEEAGMTALQTAVGDRYVVEEMKKHQYTLGGEQSGHLIFLDHSTTGDGMLSGVQLAEIVKSTGRKLSELAAEMPVYPQKLVNIRVTNKNDAMNGERVLATIQEAEAEMAGNGRILVRASGTEPLVRVMAEAPTAEECDRYVEKIAQVVREDYGVDG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: NUOF_RICRS
Sequence: MLKEEDKIFTNLHGQQSHDLKSSKKRGDWENTKALLDKGRDFIVEEVKKSGLRGRGGAGFSTGMKWSFMPKNLEKSCYLVVNADESEPGTCKDRDILRFEPHKLIEGCLLASFAIGANNCYIYIRGEFYNEASNIQRALDEAYKEGLIGKNSCGSGFDCNIYLHRGAGAYICGEETALLESLEGKKGMPRLKPPFPAGFGLYGCPTTINNVESIAVVPTILRRGASWFAGIGKPNNTGTKIFCISGHVNKPCNVEEAMGISLKELIEKYAGGVRGGWDNLKAIIPGGSSVPLLPKSLCEVDMDFDSLRTAGSGLGTGGIIVMDQSTDIIYAIARLSKFYMHESCGQCTPCREGTGWMWRVMMRLVKGNVTKSEIDELLNVTKAIEGHTICALGDAAAWPIQGLIRHFRSEIEARIKSYSVV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit F, NADH dehydrogenase I subunit F, NDH-1 subunit F.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
Protein: HSE1_SCHPO
Sequence: MFRGKPNSIETLILQATDEKNTKEKWDVIMDACDQLSSTSGDVGRNSIKFLNKRLDTANANIQLLALTLTDAIVKNCKTSIVREISSRTFTDSLLKIASDSTTHNRVRSRIAVLVNEWAEIMKKDPNMSLMQDICEKIRKLDIVDLRAPKKPEKEAMNELELKREEEELQYALALSLSESTAQSNKVENPQSTKDEPLQKTNQRQESNLATSPASTVSRVRALYDFAATEQGELSFKKGDIILVLESVYKDWWKGSCKNAVGIFPVNYVQRVVEPTIEQQRQSAHMEQQVFDALPQIDELLDTLSTTSPDAADDDALQGKYHAMIALRPKLVRLIEKYASQKEELMDLNERLLVARRDYEKLYEQSMSEMRNF
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein hse1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCAM_ACACA
Sequence: SSMFVWNTKLILKTCGTXL
What is the function of this protein?
S-adenosylmethionine decarboxylase is essential for the biosynthesis of spermine and spermidine.  The alpha subunit contains the active site.
What are the official names of this protein?
S-adenosylmethionine decarboxylase subunit alpha, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: TCYJ_BACSU
Sequence: MNKRKGLVLLLSVFALLGGGCSQTNNKTDRQAQTVIVGTGTDFPNIAFLNEKGELTGYDIEVMKAIDKELPQYTFEFKTMDFSNLLTSLGNKKIDVIAHNMAKNKEREKRFLYHKVPYNYSPMYITVKEDNHKIHTLKDLHGKTVIVGATSNAADYITKYNKTHGSPIHLKYAGQGSNDTANQIETGRADATIATPFAVDFQNKTHAFRQKTVGDVLLDTEVYFMFNKGSQTLADDTDQAIKKLEKNGTLKKLSRKWLGADYSKSSFEK
What is the function of this protein?
Part of the ABC transporter complex TcyJKLMN involved in L-cystine import.  Is also involved in cystathionine, djenkolate, and S-methylcysteine transport.
What are the official names of this protein?
L-cystine-binding protein TcyJ.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 3 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: TRPA_BRASO
Sequence: MTSRMDARFAQLKSEGRSAFVTFVMGGDPDPETSLAIVKALPQAGADIIEIGMPFTDPMADGPSIQAAGLRALKAGMTLRKTLQLVRSFREGDAATPIVLMGYYNPIYIYGVDKFLDDAKSAGVDGLIIVDLPPEEDDELCIPALKAGLNFIRLATPTTDDKRLPAVLANTSGFVYYVSITGITGAAAADSSAVGSAVARIKRHTALPVCVGFGIRTPETARAIAAHADGAVVGTALVDALKASLDAEGRATAKTVNAVADLAAALAQGVRGAQQAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: CRCB_ECO8A
Sequence: MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIGAFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLNVFVNLLGSFAMTALAFWLFSASTAH
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSPLD_VITVI
Sequence: MNGLKTPPEIGIQLPEAKVAAETGTMSGPLVPPRSDRSVRRGTDVAHVVLRFVCLLTSVIALSLMATAKEAASISIYGFLLPVSSKWSFSDSFEYLVGVSAAVAAHALLQLIISVSRLLRKSPVIPSRNHAWLIFAGDQAFAYAMLSAGSAASGVTNLNRTGIRHSPLPNFCKPLRSFCDHVAASIAFTFFSCFLLATSAILDVIWLSKY
What are the official names of this protein?
CASP-like protein 3A1, VvCASPL3A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: URE1_PAEAT
Sequence: MSFEIPRKQYAQLYGPTTGDSIRLADTELFLEIEKDYTVYGEEVVFGGGKVIRDGMGQNGQLTRAEDIPDTVITNVIVLDYTGIYKADIALKDGHIFKIGKAGNPQITDGVDIVIGASTEIIAGERKILTAGGIDTHIHFISPEQVPAALCNGITTMVGGGTGPAEGTKATTITPGAWHISRMLQAAEGLPVNIGLFGKGHASAVEPLAEQIRAGAVGLKVHEDWGSTTSSIDMSLRVADEYDVQIAIHTDTLNECGFVEDTIRAIDGRVIHTFHTEGAGGGHAPDIIKIAGLPNVLPASTNPTLPYTRNTIEEHLDMLMVCHHLNPDIPEDVAFADSRIRAETIAAEDVLHDLGIFAITSSDSQAMGRVGEVVTRTWQVADAMKRQRGALHDPSGAPHGSAESDNFRLKRYIAKYTINAAIAQGMADVIGSVEEGKFADLVLWDPAFFGVKPELVIKGGQIAYALMGDANASIPTPQPRTMRPMFATYGKALQQTSITFLSQAAIDAGVPAELGLQRIIKPVSGIRNLTKADLKYNGETPDIAVDPETYKVTVDGVEVTSQPSDVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDOC1_HUMAN
Sequence: MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASLLRQVRPPSCPVPFPETFNGESSRLPEFIVQTASYMLVNENRFCNDAMKVAFLISLLTGEAEEWVVPYIEMDSPILGDYRAFLDEMKQCFGWDDDEDDDDEEEEDDY
What is the function of this protein?
May have an important role in the development and/or progression of some cancers.
What are the official names of this protein?
Protein LDOC1, Leucine zipper protein down-regulated in cancer cells.
What is the protein family that this protein belongs to?
Belongs to the LDOC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FASC_ECOLX
Sequence: MIMGQLMNMRELFNKKKLHALVFSMWCVNLHASSLSDGIAIEPFEINAKSNRFVEFKVYNNTDEDYIVTQKVVSEENSIKKAKIPFVVNPPIRLLRKRSDAAMGIIYLNEGEVFDKKRKYYLSVSFIPKKKDSDDLGFNIIFTQQIAVKLSALN
What is the function of this protein?
Could be required for the biogenesis of a putative fimbria.
What are the official names of this protein?
Protein FasC.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
Protein: PNP_WIGBR
Sequence: MLKATIQKFQYGKNIVTIETGMIARQATSAVMVRMDDTSVFVTVVADKKEKLGQKFFPLTVNYQERTYSIGRFPGGFFRREGRPNENEVLVSRLIDRSVRPLFPKNFFNDIQIIATVMSVNPQVNPDIVSIIGASAALSLSGLPFKCPIGSSRIGYIDNKYILNPTTSELIDSKLDMIVSGSSNAVLMVESSSNILQEKNILEAILFGNEQNKIVIENIDKLKKKFKKENLEYDLKSLNNNDIQFVIEDLFFDRIKDSYKIPEKKKRLEKIENIKNDILNNFINNNNTNEEEILYIIQNIERKIVRNRIISGKPRIDGRTEDMVRNLDIHLGILPRTHGSSLFTRGETQALVTTTLGTERDAQNIDDLVGDKIDRFLFHYNFPPYCVGEVGIISSPKRREIGHGKLAKRGMLAVMPDIDKFPYTIRIVSEITESNGSSSMASVCGASLSLMDAGVPISSSVAGIAMGLIKEKDKFVVLTDILGDEDYLGDMDFKVMGTREGVTALQMDIKIEGITSEILQVSLDKAKNARINILNEMDKVIKKPKNEISIFAPRIYKIKINPEKIKDVIGKGGSVIRMLTEKTKSSIEIEDDGTVKVISTDIKNAQCALKKIKDITHEIKINKIYVAKITRISEFGIFACLINNKEGLIHVSKIPYKKFSDINNNFKIGQIISVKVIEIDRYGRIRLSFTGTDKNKNKKFFNKNN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPE_HAEIN
Sequence: MKNMLLLSSSKYKNTGYLEHTIPWLQNFLADYRGKTIAFVPYAGVSRTFDEYEKTVQNALSDLGMNIVSVHRGKQHRDIIEQADVIAIGGGNTFCLLKQLYEHNLIDIIREKVNNGTPYFGWSAGANVAGSSIMTTNDMPITYPPSFQALQLFPHQINPHFISGKMQGHNGESREERLAEFLLVNPTALVYALPEGSALHIQNGMGNRIGRKSYFVLQ
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_RICPU
Sequence: MLELFFEYIFPLIIIALKVVAITTPLILCVAYLTYAERRVIGLMQLRRGPNVVGPFGLLQPIADAVKLLFKEPIIPTNSDKILFILAPMITFILSLIGWAVIPFAKGVVLADINVGVLYILAISSLSVYGIIIAGWASNSKYAFLGAIRSSAQMISYEVSMGLVIITVLLTTGTLNLSEIIEAQRTMPWWIDLMLLPMGVVFFISVLAETNRLPFDLPEAESELVAGYNVEYSSMGFALFFLGEYANMILVSAMTTTFFLGGYLPPFNISWLDCIPGFFWFVFKVGFLLFCFLWIRATLPRYRYDQLMRLGWKVFLPLTLFWVVLVSSVLVYTDNLPSI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.