PharMolix/UniProtQA huggingface dataset:
Protein: VE2_HPV30
Sequence: METLCQRLDACQEKILDCFENDSKKIEDHIVYWKAVRHENVVLYKARQNNITKLRHQVVPCLQVCKAKACVAIEIQMALESLYKTEYKVEEWTLKDVCENMWHTAPKQCFKKSGKRIEVWFDGKKDNRTEYVVWQWVYYCGDNGWTKVPSVVDYKGIYYVHDGNKVYYTDFNDEAVKYGYKGTWEVHMGNESIYCPDSVSSTLRSNVSPVETVVEYNTYNTYQTPTTSTPVGANEAASSARPGKRPRTTEPDSTDTTRQSAARESHANRVNTNNTNNRQCLGGATCYNTEVDGGYKTTPVVHLKGEPNRLKCLRYRCQKHKHLFVNISSTYHWTNTHTEYSYITVVYKDETQRANFLNVVKIPPSIKIVMGHMTGVDM
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: ADG3_SCHPO
Sequence: MPSKIEKICLLLLGFTAASNVNAYSHRRAGDTLHHRHKHEKHNDLTDSSYEPLTLSYNDTQIQQLQRRDTVQCAFPYGDKMVAVTPDEGNAGWAMSPDQYCTAGTWCPYACEPGYLMGQWDPNATSYTYPESMYGGLYCNSDGVAVKPFPSKDYCYPGVGDLSVVDQTGDGIAFCQTVLPGNEAMLIPTWVAPDSEQVLAVPDISYWDETAAHYYVNPPGVSTTDGCVWGTSANPYGNWAPYVAGANMDENNITYVKLGANPIYLDDSYWSTVKPTYGLALECEGDTCSGLPCYVDPRENGVQGCPEGSPIGAGGACFCVVGFQQGTTAKIVVVDYSEEMASSSSSASATATSSAESSIATSPITSSSNVVSSISTSSMDSSAVSSYSVVQSSLASIISNAYIATSKSGLNSGVSTLLASPTSSSTFVTSLLRRSSIDGSASSSSASLAVPTVSSSTTGSLHYKTTTTVWVTEVFTRYLGDDSTPVTSSSIFSTATEATDTSVQTSSAIYDSSSTSNIQSSSSVYASSTGALSSNSLSSSTSSVSTSYIPNASSSVYASSTEALSSNSLSSSTSSASTSYIPSASSSYEVASNSSDYYSQTVSSITASGTTSSTSEIVSTPASNSNTGSLNGTSSFNVNSVGPSSSQTTPTSSSSITGSQSLKETSSPAYVSSTVSYTSSSVDSSSTYNSTGSSSSDSQSFSGTTYSDPTTTITSEVSSILSSPTSMQSSVSRPQSSGDASGFNTIFTSISQSSDGETSGYTISSNSSQNSASEPQTAFTSSSSSATPTITQSSISTSVSSQSSMNSSYSSPISSNSVTSSTSIISSIASSSYTSIPSISSIASSFFDASGFTSIYNGTKAGFSSSFALASNSESGASDVLSSTIAKPTFKFSTSNSGSTSYSIPSSSSRNEGTTSYSSNITVTSSTLKPSLTSSVSTASSYIASSASSNTLSTEPKTFSSSSTLSESISSINTNSLTVKPESSLSSSTTSGLTSSSSTIPSSTRSESNSESASTSSASKRSSSSTSLVQSNPVKTVVSLESYKFTTSKISLVKNPTKTYTVTDVETNVVVQTHTVSYVEHSTSYTWVHTTLYEYADVEASTKSTSEPSAKSKRNAVSTFETVFLKSKSSA
What is the function of this protein?
Cell surface beta-glucosidase involved in cell wall biogenesis,.
What are the official names of this protein?
Probable secreted beta-glucosidase adg3.
What is the protein family that this protein belongs to?
Belongs to the SUN family.
What are the subcellular locations of this protein?
Secreted.
Protein: RLMH_LACLM
Sequence: MKIKLVVVGKLKEKYLKDGIAEYVKRMGTMLPLEIIELADEKIPDNASEKEAEALKKREGDKILSRIQTGDKLAILAIQGKLMSSEELADFVKKAEVYGTGNLVFVIGGSLGLSEEVYKRSDLQISFGRMTLPHQLMRLVLVEQIYRAQMINRGSVYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_XYLFA
Sequence: MSDVTVANYHAFPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLKDYVGRPSPIYHAERLSRKVGGAQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIERQQINVYRMKLLGATVVPVTSGSATLKDALNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVGREARAQMIEDYGRLPDAMTACVGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAASIVAGRPGVLHGNRTYVVCDDDGQILETHSVSAGLDYPGVGPEHAFLADSGRVQYVGIRDEEALAAFHLLAHTEGILAALESSHAVAHAMTLARDLPKDALVLCNLSGRGDKDVHTIAAREGVRV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GRAB_HUMAN
Sequence: MQPILLLLAFLLLPRADAGEIIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIKEQEPTQQFIPVKRPIPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSNKAQVKPGQTCSVAGWGQTAPLGKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELCVGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNNGMPPRACTKVSSFVHWIKKTMKRY
What is the function of this protein?
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse (PubMed:3262682, PubMed:3263427, PubMed:1985927).  It cleaves after Asp (PubMed:8258716, PubMed:1985927).  Once delivered into the target cell, acts by catalyzing cleavage of gasdermin-E (GSDME), releasing the pore-forming moiety of GSDME, thereby triggering pyroptosis and target cell death (PubMed:32188940, PubMed:31953257).  Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution.  Cleaves caspase-3, -9 and -10 (CASP3, CASP9 and CASP10, respectively) to give rise to active enzymes mediating apoptosis (PubMed:9852092).  Cleaves and activates CASP7 in response to bacterial infection, promoting plasma membrane repair (By similarity).
What are the official names of this protein?
Granzyme B, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Secreted. Cytolytic granule. Note=Delivered into the target cell by perforin (PubMed:20038786).
Protein: SYFA_PELPB
Sequence: MENTIRSLQQEIIDFEITTAADLEAFRLRYTVRKGLIAALFGQLKTVEPAEKPRMGQLLNQLKQTADAKLTEAEERLAGTESKSSSNRIDLTLPGRRYFTGSEHPVQKVLGEMKSIFSAMGFGIATGPELETDQYNFDLLNFPPDHPARDMQDTFFVTSGNPGSDVLLRTHTSPVQIRVMLDQKPPIRVICPGKVYRNEAISSRSYCVFHQLEGLYIDKKVSFADLKATIYSFAKQMFGTDVKLRFRPSFFPFTEPSAEVDVTCYLCGGKGCKVCKKSGWLEIMGCGMVHPNVMRNCGIDPEEWSGYAFGMGVDRTVLLRYKIDDIRLLFENDLRMLKQFTA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGLB_ASPTN
Sequence: MRLSVSLGLASLWTAIGATALNVSQTNSSITLANDRLTAIFSNAGKVVDLYLDGQDLLGPASGSTGVGPYLDCYCTPKGFYTAGSTTPRMEVVQGTDATGTQYAGVILNDTYTPTGQQFQQYWFLRDGETGLHMFSRLAYYNETTPFLRNLQEFRTLFRPNTDLWTHLTSSELQTAPLPSDEAVGKQVVVQDATWRFNNTPNDAYYTQFSEYFTKYTFSNAWRDNNVHGLYADGSTSNGTTFGAWLVMNTKDTYYGGPLHSDLTVDGIVYNYIVSNHHGEGTPNITNGFDRTFGPQFYLFNGGGSSSLNELRSEAESLADPSWNVEFYDSIAKHVVGYVPSSKRGSVQGQIKLPRGATRPIAILTVDGQYFQDNSVDPRSYQYWVEMDANGKFQLDHVVEGKYRLTVYADGIFGDYVRDGVQVRGRKTTRINDSWQPESAGVEVWRLGTPDKSSGEFLHGVARDPTHPLHPPEYLIYWGAYDWQQDFPNGVNYTIGSSDPATDFNTVHWSVFGPTPDNPDVEYDTTHDWAINFSLTKKQLQKRKTATLTIQLAGAKTASGNTDVYKPDEPYTNLALESYINQQEEPLTMLIGFNQSSSCIVRSAVSCYQVRSRMTFPADWLQVGSNTLTLHLPRNATDVEDAILPGTVYVQYDALRLELS
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Degrades the rhamnogalacturonan I (RG-I) backbone of pectin (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonate lyase B.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS5_XYLFT
Sequence: MTEVALIDAGGANLGSVRYALQRLGVEPRLVCDARGLEGAARVILPGVGSAPEAMARLNNQGLIEPLLRLQVPLIGICLGMQLLFEHSEEGDVPCLGLLPGRVRRLTPAPSIRVPHMGWNRLLPLRASPLLAEVPEGANAYFVHSYAVPLTTAAVAACDHGGMFTAIVQQGVRCGAQFHPERSAETGARILRNFLEMDAA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS15_ARATH
Sequence: MGNKIARTTQVSATEYYLHDLPSSYNLVLKEVLGRGRFLKSIQCKHDEGLVVVKVYFKRGDSIDLREYERRLVKIKDVFLSLEHPHVWPFQFWQETDKAAYLVRQYFYSNLHDRLSTRPFLSLVEKKWLAFQLLLAVKQCHEKDICHGDIKCENVLLTSWNWLYLADFASFKPTYIPYDDPSDFSFFFDTRGQRLCYLAPERFYEHGGETQVAQDAPLKPSMDIFAVGCVIAELFLEGQPLFELAQLLAYRRGQHDPSQHLEKIPDPGIRKMILHMIQLEPEARLSAEDYLQNYVGVVFPNYFSPFLHTLYCCWNPLPSDMRVATCQGIFQEILKKMMENKSGDEIGVDSPVTSNPMNASTVQETFANHKLNSSKDLIRNTVNSKDEIFYSISDALKKNRHPFLKKITMDDLGTLMSLYDSRSDTYGTPFLPVEGNMRCEGMVLIASMLCSCIRNIKLPHLRREAILLLRSCSLYIDDDDRLQRVLPYVVALLSDPTAIVRCAAMETLCDILPLVRDFPPSDAKIFPEYIFPMLSMLPEDTEESVRICYASNIAKLALTAYGFLIHSFQLSDVGVLNELNSQQISTTPASETPSHLQKANGNAQLQQLRKTIAEVVQELVMGPKQTPNVRRALLQDIGELCFFFGQRQSNDFLLPILPAFLNDRDEQLRSVFFEKIVYVCFFVGQRSVEEYLLPYIDQALSDQTEAVIVNALECLSTLCKSSFLRKRALLQMIECVYPLLCYPSQWVRRAVVTFIAASSECLGAVDSYAFIAPVIRSYLSRLPASIASEEGLLSCLKPPVTREVVYRIFEKTRNPEFMAKQRKMWYSSSPQSKDWESVDLFDKDAGELNSVECRAEQKQSVEGKKQIKSASKQPEVQGKYAEKDAKLRIPRNPRPNASNTVELRDPVYPEKLQFSGFMAPYVSGANSFIEPENIPLYSFSMDKRAATNPPVASESSLQMNSLGMGSLSVPWMDSMSKSFNLASSVPVPKLISGSFHVGTNPKQFYRVVHEPESRENDQISSAISKFQDLGVSSSSKSASVTSEDASSPADLVGEPSLSRTSVPDSGWKPRGVLVAHLQEHRSAVNDIATSSDHSFFVSASDDSTVKVWDSRKLEKDISFRSRLTYHLEGSRGMCTTMLRNSTQVVVGASDGVIHMFSIDHISRGLGNVVEKYSGIVDIKKKDVKEGALVSLLNYTADSLSGPMVMYSTQNCGIHLWDTRSDLDAWTLKANPEEGYVSSLVTSPCGNWFVSGSSRGVLTLWDLRFRVPVNSWQYPIICPIEKMCLCFLPPSVSVSTTMKPLIYVAAGCNEVSLWNAEGGSCHQVLRVANYENETDVSEFQWKLPSNKVNPKPNHRQNMSSKYRIEELNEPPPRLPGIRSLLPLPGGDLLTGGTDLKIRRWDYSSPERSYCICGPSLKGVGNDDFYELKTNTGVQFVQETKRRPLATKLTAKAVLAAAATDTAGCHRDSVQSLASVKLNQRLLISSSRDGAIKVWK
What is the function of this protein?
Serine/threonine-protein kinase required for cytoplasm to vacuole transport (Cvt) and autophagy as a part of the autophagy-specific VPS34 PI3-kinase complex I (By similarity).  Required for pollen development and germination, probably via the modulation of phosphatidylinositol 3-phosphate (PI3P) formation and vacuolar organization (PubMed:21833541, PubMed:22361507).
What are the official names of this protein?
Serine/threonine-protein kinase VPS15, Vacuolar protein sorting-associated protein 15, AtVPS15.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Endosome membrane; Lipid-anchor.
Protein: LPXC_ACIET
Sequence: MLQQRTIKTLTRAVGVGLHSGQRVELTLRPAQPDTGIVFRRVDLPEPVDIPITATAVVDTRMASTIGAGGAKVHTVEHLMSACAGLGLDNLYIDITAEEVPILDGSSASFVFLLQSAGVELQNAPKRFIRVKRPVEVREGTGQQLKWARLEPYHGFKLRFDIDFAHPAVDSTGQSAEFDLGEGNYARDIARARTFGFTKDVEMLRSSGLALGGGLDNAIVMDDYKVLNADGLRYDAEFARHKILDAMGDLYLVGKPLLAAYSAFRSGHAMNNLLLRELLAHEDAWEIVTFENERQAPAGFTQPVRAW
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PHCA_SYNY3
Sequence: MKTPLTEAVSTADSQGRFLSSTELQIAFGRLRQANAGLQAAKALTDNAQSLVNGAAQAVYNKFPYTTQTQGNNFAADQRGKDKCARDIGYYLRIVTYCLVAGGTGPLDEYLIAGIDEINRTFDLSPSWYVEALKYIKANHGLSGDARDEANSYLDYAINALS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin alpha subunit.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: METB_HELPJ
Sequence: MRMQTKLIHGGINEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHAVFSLLQSGDHVLLGDDVYGGNFRLFNKVLVKNGLSCTIIDTSDLSQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKEHNLLTIVDNTFATPYCQNPLLLGTDIVAHNGTKYLGGHSDVVAGLVTTNNEALAQEFDFFQNAIGGVLGLQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNHELAKAQMRGFSGMFSFTLKNDSEAVAFVESLKLFILGESLGGVESLVGIPALMTHACIPKAQREAAGIRDGLVRLSVGIEHEQDLLEDLDQAFAKIS
What is the function of this protein?
Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction.  In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity).
What are the official names of this protein?
Cystathionine gamma-synthase, CGS, O-succinylhomoserine (thiol)-lyase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REG3G_HUMAN
Sequence: MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKSWMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGWEWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD
What is the function of this protein?
Has bactericidal activity against L. monocytogenes and methicillin-resistant S. aureus.
What are the official names of this protein?
Regenerating islet-derived protein 3-gamma, REG-3-gamma, Pancreatitis-associated protein 1B, PAP-1B, Pancreatitis-associated protein IB, PAP IB, Regenerating islet-derived protein III-gamma, REG III, Reg III-gamma.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: RTCA_MACFA
Sequence: MAGPRVEVDGSIMEGGGQILRVSTALSCLLGLPLRVQKIRAGRSTPGLRPQHLSGLEMIRDLCDGRLEGAEIGSTEITFTPEKIKGGIHTADTKTAGSVCLLMQVSMPCVLFAASPSELHLKGGTNAEMAPQIDYTVMVFKPIVEKFGFRFNCDIKTRGYYPKGGGEVIVRMSPVKQLNPINLTDRGCVTKIYGRAFVAGVLPFKVAKDMAAAAVRCIRKEIRDLYVNIQPVQEPKDQAFGNGNGIIIIAETSTGCLFAGSSLGKRGVNADKVGIEAAEMLLANLRHGGTVDEYLQDQLIVFMALANGVSRIKTGPVTLHTQTAIHFAEQIAKAKFIVKKSEDEEDASKDTYIIECQGIGMTNPNL
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase, RNA terminal phosphate cyclase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: YJHX_SALPK
Sequence: MNLSRQEQRTLHVLAKGGRITHIRDASGRVTAVECYSREGLLLADCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQPDNR
What are the official names of this protein?
UPF0386 protein YjhX.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: VF466_IIV6
Sequence: MNMPGKTPIEKIVSLSAKPFKVSRGSPRDDKERSYENTFRTPIPYNCPDVSTHLSDCPVCSNLYGKEKLLYIFLGAMIVIIFLVIKNQLN
What are the official names of this protein?
Uncharacterized protein 466R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 466R family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DDLA_BRUME
Sequence: MASGKMRIVVLFGGRSAEHDVSVLSATNVMNALDPAKYEAVPVFVTRAGQWLLSRFVNGALEKPSSGAELCLVPGGCGRAIVVPDAGAPYEADKIDIIFPVLHGLHGEDGAVQGLAQVARVPLAGCGIPGSANALDKDIAKRLVNEAGLSTAKSVTITREEVPAFSALEQALGLPIFIKPARQGSSVGVHKVVTEADYQAAMSDGFIYDDKLLAEEFIQAREVECGVLEDEGGALFVSRAGEIVPAESHCFYSYDAKYIDADGTEIKVPAELPEQVENEIRAIAAKAFRVLGCDSMARVDFFVTADRRIVLNEINTIPGFTDMSMYFKVMAVSGVSYPEIINRLVAHGLARGS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase A, D-Ala-D-Ala ligase A, D-alanylalanine synthetaseA.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_HAMD5
Sequence: MSKKDYYEILGIAKNANEQDIKDAYKRLAKKYHPDRNKDKDAETKFKEMKEAYEVLSDQQKRAAYDQHGHTAFEQSGMGGGFHNSSNFSNVFNDVFSDFFGGHQQRTQRGRDLRYTLNLTLEEAVRGASKEIHITTLVHCEHCKGSGAKQGTRPVTCTTCRGVGEVHMQQGFFTIQQTCPRCHGQGQMIKDPCRQCRGQGKVEEPKTFSVKVPAGIDSNDCLRLNGKGEVGEMGAPSGDLYVQIHVDRHHIFERSKNNLYCKVPINFTTAALGGEIEVPTLDGAIKLKIPPETQTGQCFRIPNKGIKPEKKTPGDLFCTVFIETPVHLNEKQKKLLRDLDQSFCETSSKKNTPETKKFLESMKKFFDNLTH
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG2_PSEPK
Sequence: MARTTPIELYRNIGIVAHVDAGKTTTTERILFYTGVNHKMGEVHDGAATMDWMAQEQERGITITSAATTAFWQGSTKQFAHKYRFNIIDTPGHVDFTIEVERSLRVLDGAVVVFSGADGVEPQSETVWRQANKYHVPRLAYINKMDRQGADFLRVVKQIDQRLGHHPVPIQLAIGSEENFMGQIDLVKMKAIYWNDADQGTSYREEEIPAELKALADEWRAHMIEAAAEANDELTMKFLDGEELSIEEIKAGLRQRTIANEIVPTILGSSFKNKGVPLMLDAVIDYLPAPSEIPAIRGTDPDDEEKHLERHADDKEPFSALAFKIATDPFVGTLTFARVYSGVLSSGNAVLNSVKGKKERIGRMVQMHANQRAEIKDVCAGDIAALIGMKDVTTGDTLCDMDKPIILERMDFPDPVISVAVEPKTKADQEKMGIALGKLAQEDPSFRVRTDEETGQTIISGMGELHLDIIVDRMRREFNVEANIGKPQVAYREKIRNTCEIEGRFVRQSGGRGQYGHCWIRFAPGDEGKEGLEFINEIVGGVVPREYIPAIQKGIEEQMKNGVLAGYPLINLKAAVFDGSYHDVDSNEMAYKIAASMATKQLSQKGGAVLLEPVMKVEVVTPEEYQGDILGDLSRRRGMIQDGDETPAGKVIRAEVPLGEMFGYATSMRSMTQGRASFSMEFTRYAEAPASIADGIVKKSRGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUP15_CAEEL
Sequence: MVNSLSRILFCSLLIFSVISLREERLETAPITDDPWDLDGPCQKYVEKLAVVQSEMVACATNWSIPPVVCTKCFQNYINFKQFEYETKNLNNVYSLDNRTCSQVIYDNYLLSYSTDISKALTSEIWEKSRCDSCITIKWNFPQNKSEVSFSERTMQFQNRMYEWRNCVVNYTSGGVLDDNLTNGSKICNLCKTTFDELFGYYWKIYTTPDVDFCVDVETTMNDTIHLWDDVWKCAEKQDRNRDLFGIMITFGTLLLLTALFYAASYIQGGGETRRLIQYARLSDPHGQRSRLLSSGMSDADLVSRVSPGSSVLYNVPIHQTR
What is the function of this protein?
Modulates the transport of substances from the endosomal to lysosomal compartments.  Plays a role in lysosome formation and function in coelomocytes.
What are the official names of this protein?
Coelomocyte uptake defective protein 15.
What is the protein family that this protein belongs to?
Belongs to the OSTM1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TFIIS_ASFP4
Sequence: MKMHIARDSIVFLLNKHLQNTILTNKIEQECFLQADTPKKYLQYIKPFLINCMTKNITTDLVMKDSKRLEPYIILEMRDIIQMMFFRTLQKHMFFKEHTDLCTEYAQKIEASCYHYTYQQQEKTFLEEYSTRCGTINHIINCEKKSHQQQDNDALNKLISGELKPEAIGSMTFAELCPSAALKEKTEITLRSQQKVAEKTSQLYKCPNCKQRMCTYREVQTRALDEPSTIFCTCKKCGHEFIG
What is the function of this protein?
Putative initiation factor.  Necessary for efficient transcription elongation past template-encoded arresting sites.
What are the official names of this protein?
Transcription factor TFIIS homolog.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family.
Protein: CHS1_EXOEX
Sequence: EFLFARTMIGVFKNIEYMCNRTSSKTWGKEAWKKIVVCIVSDGRAKINTRTRAVLAGLGVYQDGIAKQQVNGKDVTAHIYEYTTQVGLELKGTQVSLKPRSATPVQLLFCLKEKNQKKINSHRWFFQAFGRVLDPNICVLIDAGTKPGKDSIYQLWKAFDLEPMCGGACGEIKVMLDHGKKLYNPLIAT
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DGTL1_BIFLO
Sequence: MPLTCAERHIFGKSAPISRICAVELTSVAHIREVGITAADMCAYAWHMETTLDGEQVLSDEGYNAFDEERWAPEPPKSKSRTAFERDRARLIHSSALRRLGAKSQILIAGTDDFARTRLTHTLEVAQIGRQIGALLGCDPDVVDCACLAHDLGHPPFGHNGERALADIAGNIGGFEGNAQTMRILTRLEPKIFHPDGRSAGVNLTRAALDAAVKYPWTLAEADRHPKGERSKKFCVYPDDEPVFRWLKIGAPQAAKPMECQIMDLSDDIAYSVHDVEDSIATGAFDPIVLADPKMLDHIIEQTRAWYGAKWDADKLLAAFMRLRREHLFPAHFNGSRESLAQLKNITSDLIGRFCWSVETATRDTYGPGPLTRYSSNIVIPEDTNYEIVALKGIAVYFVMAPREREPFHQEELKIVSDLVDVLMADSPLPSDALESQFLADWNESTNDNERLRVAIDQVASLTDNSALALHSILC
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: YBEY_ECODH
Sequence: MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_NITMU
Sequence: MTASKSTETLPGDNTNTWSGRFDEPVSELVQRYTASVGFDKRLAEYDIQGSLAHARMLAAGGIIGPHDLDAIERGLSQIRQEIQGGGFVWQLALEDVHLNIEKRLTALIGDAGKRLHTARSRNDQVATDIRLYLRASIDRITALIHAMQKALLHLAEQHVDTVMPGFTHLQVAQPIVFGHHLIAYFEMLKRDVERLADCRKRVNKLPLGAAALAGTSYSVDRAMVAQELGFEGVCENSLDAVSDRDFAIEFCAAAALIMTHLSRLSEELILWMSPPFGFIDLADRFCTGSSIMPQKKNPDVPELVRGKTGRVNGHLVALLTLMKAQPLAYNKDNQEDKEPLFDTVDTLTDTLRIYADMMAGIRVKETAMREAAKRGYATATDLADYLTKKGLPFREAHEAVAQAVRFAEKNNRDLSALTLPELQQFSPLIEDDIFTVLTLEGSLNSRNHIGGTAPVQVAAAIRRAREWLSATPAAQ
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.