PharMolix/UniProtQA huggingface dataset:
Protein: MNHD1_STAA3
Sequence: MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVYFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit D1, Mnh complex subunit D1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit D family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BATF2_HUMAN
Sequence: MHLCGGNGLLTQTDPKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHESLEKDNLALRKEIQSLQAELAWWSRTLHVHERLCPMDCASCSAPGLLGCWDQAEGLLGPGPQGQHGCREQLELFQTPGSCYPAQPLSPGPQPHDSPSLLQCPLPSLSLGPAVVAEPPVQLSPSPLLFASHTGSSLQGSSSKLSALQPSLTAQTAPPQPLELEHPTRGKLGSSPDNPSSALGLARLQSREHKPALSAATWQGLVVDPSPHPLLAFPLLSSAQVHF
What is the function of this protein?
AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system.  Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system.  Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity).  Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma.  Possibly acts by interfering with AP-1 binding to CCN1 promoter.
What are the official names of this protein?
Basic leucine zipper transcriptional factor ATF-like 2, B-ATF-2, Suppressor of AP-1 regulated by IFN, SARI.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YJBJ_ECOL6
Sequence: MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQERYGYQKDQAEKEVDSWEKRHDYRW
What are the official names of this protein?
UPF0337 protein YjbJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: KLF11_HUMAN
Sequence: MHTPDFAGPDDARAVDIMDICESILERKRHDSERSTCSILEQTDMEAVEALVCMSSWGQRSQKGDLLRIRPLTPVSDSGDVTTTVHMDAATPELPKDFHSLSTLCITPPQSPDLVEPSTRTPVSPQVTDSKACTATDVLQSSAVVARALSGGAERGLLGLEPVPSSPCRAKGTSVIRHTGESPAACFPTIQTPDCRLSDSREGEEQLLGHFETLQDTHLTDSLLSTNLVSCQPCLHKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLPAFLKPPPQLSVGTVRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALPPPAPCAANVMAAGNTKLLPLAPAPVFITSSQNCVPQVDFSRRRNYVCSFPGCRKTYFKSSHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHARRHMTTKKIPGWQAEVGKLNRIASAESPGSPLVSMPASA
What is the function of this protein?
Transcription factor (PubMed:9748269, PubMed:10207080).  Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269, PubMed:10207080, PubMed:16131492).  Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity).  Induces apoptosis (By similarity).
What are the official names of this protein?
Krueppel-like factor 11, Transforming growth factor-beta-inducible early growth response protein 2, TGFB-inducible early growth response protein 2, TIEG-2.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COABC_SYNY3
Sequence: MVKGKRILIGVGGGIAAYKICEVVSQLFQQGAEVRVILTAEAEKFVTPLTFTTLARHPAYGDADFWQPIHHRPLHIDLGEWADIFLIAPLTAHTLAKLGHGFADDLLSNTVLASSCPILLAPAMNTDMWEQEAVQRNLQQLLGDRRYHLLAPNGGLLACDRRGVGRLAEPAQIMHRLQALLFTGGQEDLRGKRILITAGGTQEYLDAVRFIGNPSTGKMGLALAQSAGDRGARVTLIHGPIGDLPIPMGVISMAVVNAEQMEQALAQQAPLADWIVMAAAVADVKPAQTWTGKIAKQDLPDSLPLAPVPDLIAQVSKQKRPHQLLVGFAAQAGDIVTPAKEKLQRKNLDVIVANPIDQPQSGFGTDSNQAVIIDRHGSQTAIAPCSKLAMAHRIWQYLLERI
What is the function of this protein?
Catalyzes two sequential steps in the biosynthesis of coenzyme A.  In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine.  In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
What are the official names of this protein?
Coenzyme A biosynthesis bifunctional protein CoaBC, DNA/pantothenate metabolism flavoprotein, Phosphopantothenoylcysteine synthetase/decarboxylase, PPCS-PPCDC.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PPC synthetase family.
Protein: REPB_STAAU
Sequence: MKHGIQSQKVVAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQGFRRMMQYKKINKNLVGFMRATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKVQMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYGGLLKEIHKKLNLDDTEEGDLIHTDDDEKADEDGFSIIAMWNWERKNYFIKE
What is the function of this protein?
Produces a single-strand nick in a specific site of the plasmid, and this nick results in single-strand replication by rolling circle mechanism.
What are the official names of this protein?
Replication protein.
What is the protein family that this protein belongs to?
Belongs to the Gram-positive plasmids replication protein type 1 family.
Protein: GCSP_AGRRK
Sequence: MSTPTEFTFTDYQPYDFANRRHIGPSPSEMADMLKVIGYSSLDKLIDATLPPSIRQKAPLVWGAPMTEREALDKLRETANKNKVLVSLIGQGYYGTITPPVIQRTILENPAWYTAYTPYQPEISQGRLEALLNYQTMICDLTGLDVANASLLDEATAAAEGMAMAERVAKSKAKAFFVDADCHPQTIALIKTRAEPLGWSVIVGNPFTDLDPVDVFGAIFQYPGTHGHIHDFTGLIARLHQTGAIAVVAADPLALTLLKSPGEMGADIAIGCSQRFGVPVGYGGPHAAYMAVKDAYKRSMPGRLVGVSVDARGNRAYRLSLQTREQHIRREKATSNICTAQVLLAVMASMYAVFHGPQGLKAIAQQVHQKAVLMAKGLEKLGYTIEQETFFDTITVEVGHMQGLILRAAVAEGVNLRKVGETKIGMSLDERTRPATLEAVWRAFGGNFRLADFEPGYRLPKTLLRTSEYLTHPIFHMNRAESEMTRYIRRLSDRDLALDRSMIPLGSCTMKLNATAEMLPISWPEFSDIHPFVPTDQALGYREMIDDLTEKLCAVTGYDAFSMQPNSGAQGEYAGLLTIRNYHIANGEGHRDICLIPTSAHGTNPASAQMAGMKVVVIKVSDDGDIDMADFRAKAEQYAANLSCCMITYPSTHGVFEETVKEICDLVHKHGGQVYLDGANMNAMVGLSRPGDIGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAEHLPGHPETDGRPGAVSAAAFGSASILPISWSYCLMMGGEGLTQATKVAILNANYIAARLKGAYDVLYKSKTGRVAHECIIDTRPLVDSAGVTVDDVAKRLIDCGFHAPTMSWPVAGTLMIEPTESETKAELDRFCAAMLAIREEARAIEEGRMDKTDNPLKNAPHTVEDLVGEWNRPYSREQACFPPGAFRVDKYWSPVNRVDNVYGDRNLVCSCPPVESYAEAAE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: CYPR4_CYNCA
Sequence: MFGDQRRVDFVDSGVWALKFMRDEDYREFVTRFQSCLFENVYGLKASDENKVKVYGKDFIGWVKPDVADDSMWEKDDDELWRSPSKMTPVRGSNDLLEEFEEAASDGGIQSVALGALDNSFLVNDSGVQVVKNFSHGIHGKGVYVKFDNGGKRVGGSSSGGYSNLTPQKALLMRGETNMLLMSPAKAGKPHSTGVNQLDIETGKIVTEWKFEKDGTDITMRDITNDTKGSQLDPSESTFLGLDDNRLSQWDMRDRRGMVQNIAHSDSPVLHWTQGHQFSRGTNFQSFATTGDGSIVVGSLDGKIRLYSTTSMRMAKTAFPGLGSPITHVDVTYDGKWILGTTDTYLILICSLFTDKDGKTKTGFSGRMGNKIPAPRLLKLTPVDSHTAGVNNKFHGGRFSWVTESGKQERHLVATVGKFSVIWDFQRVKNSGHECYRNQEGLKSCYCYKLMTKDESIIESLFMNDKYAAVGDSPEAPLVMATPKKITSFSMSDGKAKGKRR
What are the official names of this protein?
Protein CYPRO4.
What is the protein family that this protein belongs to?
Belongs to the VID27 family.
Protein: MRNC_SYNP6
Sequence: MFVPESDPLRGDRRLSPAAAKQLAPQALAYLGDALYEFHVRLRLLLPAQRSHQVHQSVVGAVRAERQAELLVSLLPLLTAEELEIVRRGRNAAGRVPRRLTGEYYQQATGLETLLGYLYLCDPQRLQALLQQLPVTEY
What is the function of this protein?
Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor.  Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors.
What are the official names of this protein?
Mini-ribonuclease 3, Mini-3, Mini-RNase 3, Mini-RNase III, Mini-III.
What is the protein family that this protein belongs to?
Belongs to the MrnC RNase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_WOLPP
Sequence: MAVPKRKKSKSRRNMHRSHHAIKPKNIVVCATTGEFMLPHNIAVDNSYKGKRVFIKQKAE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: RR19_LEPVR
Sequence: MTRSLKKNPFVAKHLLRKIEKLNTKAEKEIIITWSRASTIIPTMIGHTIAIHNGREHLPVYIIDLMVGHKLGEFSPTINFRGHAKNDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENOA_TRASE
Sequence: MSILKIFAREIFDSRGNPTVEVDLYTSKGLFRAAVPSGASTGIYEALELRDNDKTRFLGKGVSKAVGHVNKTIAPALISKNINVVEQEKIDKLMLEMDGSENKSKFGANAILGVSLAVCKAGAAEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGAESFKEAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILEDKEALELLKTAISKAGYTDKVVIGMDVAASEFYRDGKYDLDFKSPDDPSRYITPDQLADLYKSFIKSYPLVSVEDPFDQDDWSAWKKFTATVGVQVVGDDLTVTNPKRIAKPVEEKSCNCLLLQVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQLLRIEEELGSKARFAGRNFRNPRIN
What are the official names of this protein?
Alpha-enolase, 2-phospho-D-glycerate hydro-lyase, Phosphopyruvate hydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_HALHL
Sequence: MSLNAEQKSEIVEQFRRSPSDTGSPEVQIALLSARIQHLTEHFSVHKQDHHSRQGLLKLVSQRRKLLDYLKRKDRGRYQDVIERLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GUF1_BABBO
Sequence: MVCHRYLLGLGASTLCLRRLAQYPSTEYHGIASRHRSPGYYAYILGNFNISNEEQLFSSVHSLANNDSDVLPVEDNGTTNLTGTGEATSETGKEEEVVNEPYNGNRMRNFCIIAHVDHGKSTLADRFLELTKAVEPHEIQGQYLDNMELERERGITIKLQSALIKYTYPKDGQVYSLNLIDTPGHIDFNHEARRSIAACEGAILVVDGTKGIQAQTVTTSMIAIEAGLKLIPVVNKIDVPFCDYESTVADLTSLFDFSEDEILMASAKEGFGINEILDAVVERIPPPKINLDRPFRALVFDSQYDPHRGVVSYVRVSDGIIKKLDDVVFLGHNLESRITAVGVMMPELRERDVLRSGEVGWLCSNTKDPSKVAVGDTVALKSAVKDNNVEPLVAFAPAKPSVFAGLYPCDGSDYMRLSVALEKLKLNDHSIVFEPSESSIAGHGFKCGFNGLLHLDVTVQRLQREFDVGVIVTSPSVPYKCILKNGKEITVSDAAHWPEEGMVKVSMEPWTNVTVRIPGDCHKKVSNLLTQMRGEFQKKSEFAGGKSLVLEYKVPMIEIISTFFDNLKSMTNGFGSFDYEGTEYREIDLCKLRVLINGEEAGGLSMLVARDNAYKSGRLLVETLREVIPPKQFKINLQAAIGKRVIAALSIPALRKNVTERCSGGDPSRKRKLLENQAKGKKYMAEIGNVSIPFDAYKAVHKALR
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor GUF1 homolog, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase GUF1 homolog, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: BIOB_DESVV
Sequence: MHNLLENLRRRLLAQRTPEPLPPTSQGLARPSHDVVRGPCDADIPPDARNTMPEGITVEEALAVAELPQKHALDILATAQAIRSVHKGGPAALCGIVNAKSGRCPEDCAFCAQSSHHATGSPVHALLDAETLLRRAEELRQSGAERYGIVTSGTRLTVRELDTLCEAAVRIRRETGIALCGSLGQLTPDAAACLKEAGFSSYHHNLETSRSFFPAICSTHAYDDDIATVRAARAAGLRTCSGGIFGMGETDAQRIELSATLRELDVDSIPVNLLSPIPGTPLQHRPTMPPMRALVSIAIYRLMHPARDILVCGGREATLGPWQSWIFLAGANGMMVGNYLTTTGRDMADDLAMLATLGVRA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MMP13_XENLA
Sequence: SSLSVLVLSLSFAYCLSAPVPQDEDSELTPGDLQLAEHYLNRLYSSSSNPVGMLRMKNVNSIETKLKEMQSFFGLEVTGKLNEDTLDIMKQPRCGVPDVGQYNFFPRKLKWPRNNLTYRIVNYTPDLSTSEVDRAIKKALKVWSDVTPLNFTRLRTGTADIMVSFGKKEHGDYYPFDGPDGLLAHAFPPGEKLGGDTHFDDDEMFSTDNKGYNLFVVAAHEFGHALGLDHSRDPGSLMFPVYTYTETSRFVLPDDDVQGIQVLYGPGNRDPHPKHPKTPEKCDPDLSIDAITELRGEKMIFKDRFFWRVHPQMTDAELVLIKSFWPELPNKLDAAYEHPAKDLSYLFRGKKFWALNGYDIVEDYPKKLHELGFPKTLKAIDAAVYNKDTGKTFFFTEDSYWSFDEEARTLDKGFPRLISEDFPGIGEKVDAAYQRNGYLYFFNGALQFEYSIWSQRITRILKTNFVLMC
What is the function of this protein?
Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN.  Cleaves several types of triple helical collagen.  May also function by activating or degrading key regulatory proteins.  Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification (By similarity).
What are the official names of this protein?
Collagenase 3, Matrix metalloproteinase-13, MMP-13.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: GLPB_ECODH
Sequence: MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQLQGSVELAHQRVTPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELGLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: RL30_HYPBU
Sequence: MAAAREAEKKEEGQKQVKLYAIIRIRGRVDVHPDVEYTLKLLRLHRKFHLVLYPSTLPGIERMIHKVKDWVTWGEIDRDTLVELLRRRGRISGNKPLTDEYVQEKLGLKGGIEELADKLLKGEIMLHKLYDKQKKIWIIKPVFRLHPPRGGFKGSIKKPYGAGGELGYRGPAINELIRRML
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ZNUC_EHRCJ
Sequence: MFHRLLNKSKILACDDKSVNDYIINVKNLSFFYSKKKVIDNISFRVKFGEIITILGPNGGGKTTLIRILVGIYKNYVGLVEYAKDFTIGYLPQHFSVNSLIPMTVEYFLNSSYTNRKRKLGVGDVLKDVNIEKILDRQMSEISYGELQLVLLARCLMLNPDLIILDEPVSCMDINAKNSFYKLINKLISIYNLSVIMTSHDLHFVMSNSYRVICINKSVYCEGSPSEIVKNEKFLKMFSSYA
What is the function of this protein?
Part of the ABC transporter complex ZnuABC involved in zinc import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Zinc import ATP-binding protein ZnuC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UBIQ_WHEAT
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGQ
What is the function of this protein?
Ubiquitin exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degradation via the proteasome.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Ubiquitin.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DEOB_BUCAP
Sequence: MKRVFLMILDSLGIGSSVDACKFNDSGADTLGHIAEKCFFNEANVQRRGSLYIPNLIKLGIVKSYQSSTGKYLLGFNQKEDANIIASYGYASELSSGKDTTSGHWEIAGAPFLKDWYYFKEKDNSFPSSLINKIITKLKLPGILGNCHASGTEIIKILGEEHIKTGKPIFYTSCDSVFQIACHEIKFGLSNLYKICENIREILDQNKYQVARVIARPFIGTNKSNFNRTGNRRDISMKPLSITFMEKLIQEKQGKVIAIGKISDIYAGVGISKNIKSTGLYELCHTTIHQMKSAKNNTVIFTNFVDFDSVWGHRRDVSGYAKGLEFFDSKLSEMIDLVKEGDLFILTADHGCDPTWKGTDHTRENVPILIYSPGEEIKFLGHRDTFSDIGQTIAKYFSLSDMKYGKSMF
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BMP7_XENLA
Sequence: MNALTVKRRLPVLLFLFHISLSSISSNTILENDFHSSFVQRRLKGHERREIQKEILTILGLQHRPRPYLPEKKKSAPLFMMDLYNAVNIEEMHAEDVSYSNKPISLNEAFSLATDQENGFLAHADTVMSFANLVDNDNELHKNSYRQKFKFDLTDIPLGDELTAAEFRIYKDYVQNNETYQVTIYQVLKKQADKDPYLFQVDSRTIWGTEKGWLTFDITATGNHWVMNPHYNLGLQLSVESMDMQNVNPRLVGLVGKNGPQDKQPFMVAFFKTSDIHLRSVRSTSNKHWNQERAKTYKEQDNLPPANITDGIMPPGKRRFLKQACKKHELFVSFRDLGWQDWIIAPEGYAAYYCDGECAFPLNSFMNATNHAIVQTLVHFINPETVPKPCCAPTQLNGISVLYFDDSANVILKKYKNMVVQACGCH
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays important role in various biological processes, including embryogenesis, hematopoiesis, neurogenesis and skeletal morphogenesis.  Initiates the canonical BMP signaling cascade by associating with type I receptor ACVR1 and type II receptor ACVR2A.  Once all three components are bound together in a complex at the cell surface, ACVR2A phosphorylates and activates ACVR1.  In turn, ACVR1 propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes.
What are the official names of this protein?
Bone morphogenetic protein 7, BMP-7, xBMP7, Osteogenic protein 1, OP-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RFIP4_MOUSE
Sequence: MAGGAGWAGAPAALLRSVRRLREVFEVCGRDPDGFLRVERVAALGLRFGQGEEVEKLVKCLDPNDLGRINFKDFCRGVFAMKGCEELLKDVLSVESAGTLPCSPDIPDCVEQGSDFSGSTDGEQLPREPDFFQEDEEEAMTLALPEGPQELDMDSPMESSQGPEGSVKGCGEEKEPELGGLFLPEDKCLVLTPSVTTSDLSTHSTASLISNEEQFEDYGEGDDVDCAPSSPCPDDETRTNVYSDLGSSVSSSAGQTPRKMRHAYNSELLDVYCSQCCKKINLLNDLEARLKNLKANSPNRKISSTAFGRQLMHNSNFSSSNGSTEDLFRDSIDSCDNDITEKVSFLEKKVTELENDSLTSGGLKSKLKQENMQLVHRVHELEEMVKDQETTAEQALEEEARRHREVYCKLEREKSTELELLNTRVQQLEEENTDLRTTVARLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDLYKRMMDKLRQNRLEFQKEREATQELIEDLRRELEHLQMYKLDCERPGRGRSSSGLGEFNARAREVELEHEVKRLKQENHKLRDQNDDLNGQILSLSLYEAKNLFATQTKAQSLAAEIDTASRDELMEALKEQEEINFRLRQYMDKIILAILDHNPSILEIKH
What is the function of this protein?
Acts as a regulator of endocytic traffic by participating in membrane delivery.  Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity).  May play a role in differentiation during retinal development, in a Rab11-independent manner.
What are the official names of this protein?
Rab11 family-interacting protein 4, FIP4-Rab11, Rab11-FIP4, mRab11-FIP4A.
What are the subcellular locations of this protein?
Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis.
Protein: AMMR1_PONAB
Sequence: MAAGCCGVKKQKLSSSPPSGSGGGGDASSSSHCSGESQCRAGELGLGGAGTRLNGLGGLTGGGSGSGCTLSPPQGCGGGGGGIALSPPPSCGVGTLLSTPAAATSSSPSSSSAASSSSPGSRKMVVSAEMCCFCFDVLYCHLYGYQQPRTPRFTNEPYPLFVTWKIGRDKRLRGCIGTFSAMNLHSGLREYTLTSALKDSRFPPMTRDELPRLFCSVSLLTNFEDVCDYLDWEVGVHGIRIEFINEKGSKRTATYLPEVAKEQGWDHIQTIDSLLRKGGYKAPITNEFRKTIKLTRYRSEKMTLSYAEYLAHRQHHHFQNGIGHPLPPYNHYS
What are the official names of this protein?
Nuclear protein AMMECR1, AMME syndrome candidate gene 1 protein homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: DPO3A_MYCBO
Sequence: MSGSSAGSSFVHLHNHTEYSMLDGAAKITPMLAEVERLGMPAVGMTDHGNMFGASEFYNSATKAGIKPIIGVEAYIAPGSRFDTRRILWGDPSQKADDVSGSGSYTHLTMMAENATGLRNLFKLSSHASFEGQLSKWSRMDAELIAEHAEGIIITTGCPSGEVQTRLRLGQDREALEAAAKWREIVGPDNYFLELMDHGLTIERRVRDGLLEIGRALNIPPLATNDCHYVTRDAAHNHEALLCVQTGKTLSDPNRFKFDGDGYYLKSAAEMRQIWDDEVPGACDSTLLIAERVQSYADVWTPRDRMPVFPVPDGHDQASWLRHEVDAGLRRRFPAGPPDGYRERAAYEIDVICSKGFPSYFLIVADLISYARSAGIRVGPGRGSAAGSLVAYALGITDIDPIPHGLLFERFLNPERTSMPDIDIDFDDRRRGEMVRYAADKWGHDRVAQVITFGTIKTKAALKDSARIHYGQPGFAIADRITKALPPAIMAKDIPLSGITDPSHERYKEAAEVRGLIETDPDVRTIYQTARGLEGLIRNAGVHACAVIMSSEPLTEAIPLWKRPQDGAIITGWDYPACEAIGLLKMDFLGLRNLTIIGDAIDNVRANRGIDLDLESVPLDDKATYELLGRGDTLGVFQLDGGPMRDLLRRMQPTGFEDVVAVIALYRPGPMGMNAHNDYADRKNNRQAIKPIHPELEEPLREILAETYGLIVYQEQIMRIAQKVASYSLARADILRKAMGKKKREVLEKEFEGFSDGMQANGFSPAAIKALWDTILPFADYAFNKSHAAGYGMVSYWTAYLKANYPAEYMAGLLTSVGDDKDKAAVYLADCRKLGITVLPPDVNESGLNFASVGQDIRYGLGAVRNVGANVVGSLLQTRNDKGKFTDFSDYLNKIDISACNKKVTESLIKAGAFDSLGHARKGLFLVHSDAVDSVLGTKKAEALGQFDLFGSNDDGTGTADPVFTIKVPDDEWEDKHKLALEREMLGLYVSGHPLNGVAHLLAAQVDTAIPAILDGDVPNDAQVRVGGILASVNRRVNKNGMPWASAQLEDLTGGIEVMFFPHTYSSYGADIVDDAVVLVNAKVAVRDDRIALIANDLTVPDFSNAEVERPLAVSLPTRQCTFDKVSALKQVLARHPGTSQVHLRLISGDRITTLALDQSLRVTPSPALMGDLKELLGPGCLGS
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_PSESM
Sequence: MRKLALVPIQFYRYAISPLMASHCRFYPSCSCYAYEAIDNHGLLRGGWLSIRRLGRCHPWNPGGYDPVPAVPTSRSSSMAE
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.