PharMolix/UniProtQA huggingface dataset:
Protein: MPGP_PYRHO
Sequence: MIRLIFLDIDKTLIPGYEPDPAKPIIEELKDMGFEIIFNSSKTRAEQEYYRKELEVETPFISENGSAIFIPKGYFPFDVKGKEVGNYIVIELGIRVEKIREELKKLENIYGLKYYGNSTKEEIEKFTGMPPELVPLAMEREYSETIFEWSRDGWEEVLVEGGFKVTMGSRFYTVHGNSDKGKAAKILLDFYKRLGQIESYAVGDSYNDFPMFEVVDKAFIVGSLKHKKAQNVSSIIDVLEVIK
What is the function of this protein?
Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG).  The enzyme is absolutely specific for MPG.
What are the official names of this protein?
Mannosyl-3-phosphoglycerate phosphatase, MPGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MPGP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_LISW6
Sequence: MKRREAREKALQALFQIELNEMSLDQAIKNIMEDEQDDYMEKLVEGVMANKAEIDAIIEPNLDNWRMDRLSKVDLSLLRLSVYEINYLDDVPNRVSLNESIEIAKIYSDEKSSKFINGVLANIAPEDK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: LEU3_BACC1
Sequence: MEKRIVCLAGDGVGPEVMESAKEVLHMVERLYGHHFHLQDEYFGGSAIDLNGQPLPQRTLAACLASDAVLLGAVGGPRWDSAKERPEKGLLALRKGLGVFANVRPVTVESATAHLSPLKKADEIDFVVVRELTGGIYFSYPKERTDEVATDTLTYHRHEIERIVSYAFQLASKRKKKVTSIDKANVLESSKLWRTVTEEVALRYPDVELEHILVDAAAMELIRNPGRFDVIVTENLFGDILSDEASVLAGSLGMLPSASHAEKGPSLYEPIHGSAPDIAGKNKANPIAMMRSVAMMLGQSFGLTREGCAIEEAISAVLKLGKCTADIGGTETTTSFTKAVMQEMEEQALVGRGR
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_PINCO
Sequence: MDEFHRCGKEDSFWQQCFLYPLFFKEDLYAISHDHYLDVSSSSRPMEHLSSNDQLSFLTVKRLIGQIRQQNHSIVLFVNCDPNPLADRKKSFYSESVLEALTLVLEVPFSIWSKYSVEGMNESKSFRSIHSIFPFLEDKFPHSNSILDARIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYEYRNSTENLQRSIIVVPRVNTRFFLFLWNYYVCECESILFSRLKRSSHSRSLSHGSFPQRTHFHRKIKHIIIFSRRNSLKSIWSLKDPKIHYVRYGERPIIAIKGAHLLVKKCRYYLLIFRQFYFHLWSEPYRVCSHQLSKNCSSSPGYFLRVRMNPILVRTKMLDELFIADLITDEIDPIVPIVPIIGLLATEKFCDISGRPISKLSWTSLTDDDILDRFDQIWRNLFHYYSGSFDRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFDSLPFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKIGNLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRH_LACPL
Sequence: MSEVKYKRVILKLSGEALAGEKGFGINPPVIKTVAEELKDVYDMGVQIAIVVGGGNMWRGEAGAQMGMERAQADYIGMLATIMNALALQDNLESIGVPTRVQTSIEMRQIAEPYIRRKAMRHLEKRRIVIFAGGTGSPYFSTDTTAALRAAEINADAILMAKNGVDGVYSADPNKDASAVKFDTLTHLDIINKGLQVMDTTASSLSMDNDIPVVVFNLNEPGNIRKVVAGEHIGTTVRGK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GMHA_COXBU
Sequence: MNLFQRVKYNFEESIKTKTAAIELLVDPIVQAGELMAQCLLNEHKILSCGNGGSAADAQHFSSEMLNRFETERPSFPALALTTDASTVTAIANDYSYAEVFSKQIAGLGSTGDILLAISTSGHSKNILQAITAAHIRGMNVVALTGRDGGELFTLLGTDDIEIRVPAESTARIQETHALIIHCLCDIIDRKLIPSSEDH
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_CORJK
Sequence: MAIKTVQDLINEGVQGRHVLVRADLNVPLSDGNITDPGRIDASVPTLKALLEAGARVVVSAHLGRPKGEFKEEFSLAPVAEALAERLDQWVPLATDVTGEDAHERANGLDDGDILLLENVRFDARETSKDETERTEFAAELAALTGDNGAFVSDGFGVVHRKQASVYDVAKKLPHYAGGLVEAELNVLRKVSEAPEKPYAVVLGGSKVSDKLGVIEALAPRVDNLIIGGGMCFTFLAAKGYEVGGSLLQEDMIDTCKDLLERFGDVIALPTDVVVAERFDKDADHRTVDLNSIPEGWMGLDIGPESVKAFAEVLSKSKTVFWNGPMGVFEFPAFAEGTRGVAQAIIDATAAGAFSVVGGGDSAAAVRTLGLNEEGFSHISTGGGASLEFLEGKELPGVSVLES
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_NEIMB
Sequence: MLLIPAIDLKEGRCVRLKQGLMEEATVFSDSPAETALHWFKQGARRLHLVDLNGAFAGVPQNLPAIKDILAAVAKDIPVQLGGGIRDLKTIGQYLDLGLNDVIIGTAAVKNPDFVREACKAFPGRIIVGLDAKDGMAAIDGWATVTGHHVIDLAKRFEDDGVNSIIYTDIGRDGMMSGVNIDATVKLAQTVRIPVISSGGLTGLDDIRALCAAEKHGVAGAITGRAIYEGSIDFAQAQQLADSLD
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA1_HALH5
Sequence: MNRSRSESLFQKAQSLIVGGVNSPSRSFKAVGGGAPVFMEKAKGAYFWDVDGNQYIDYLAAYGPIITGHAHPHITNAIQRAAENGVLYGTPTKLENQFASMLQQAIPSLEKVRFVNSGTEAVMTTIRVARAYTGRDKIIKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVTKNIAEEVITVPFNQLDSLKEALDHWGEEVAAVLVEPIVGNFGIVEPHEGFLEGVNELAHNAGALVIYDEVITAFRFMYEGAQNYVGVEPDMTALGKIIGGGLPIGAYGGRIDIMEKVAPLGPAYQAGTMAGNPASMSAGIACLEVLQEEGLYDELDRKGAILEKGIKAHAEAHGITISINRLKGALTVYFTDETVTCYEQAERSDGEKFSLFFKEMLNQGINLAPSKYEAWFLTIAHTDEDIEKTLQAVDHAFSVMAAKGYHLKR
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
Protein: GLGC_SALHS
Sequence: MVSLEKNDRVMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCLNSGIRRIGVITQYQSHTLVQHIQRGWSLFSEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKGARCTVACMPVPIKEATAFGVMAVDESDKIIDFVEKPANPPAMPGDASKSLASMGIYVFDADYLYELLAADDKDDASSHDFGKDIIPKITREGMAYAHPFPLSCVQSDPQAEPYWRDVGTLEAYWKANLDLASVTPELDMYDQNWPIRTHMESLPPAKFVQDRSGSHGMTLNSLVSGGCIISGSVVVQSVLFPRVRINSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACIIPEGMVIGENAEEDARRFYRSEEGIVLVTREMLRKLQVKQER
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: TRGC2_HUMAN
Sequence: DKQLDADVSPKPTIFLPSIAETKLQKAGTYLCLLEKFFPDIIKIHWQEKKSNTILGSQEGNTMKTNDTYMKFSWLTVPEESLDKEHRCIVRHENNKNGIDQEIIFPPIKTDVTTVDPKYNYSKDANDVITMDPKDNWSKDANDTLLLQLTNTSAYYTYLLLLLKSVVYFAIITCCLLRRTAFCCNGEKS
What is the function of this protein?
Constant region of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447).  Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the epithelial boundaries between the host and external environment, including endogenous lipids presented by MH-like protein CD1D and phosphoantigens presented by butyrophilin-like molecule BTN3A1.  Upon antigen recognition induces rapid, innate-like immune responses involved in pathogen clearance and tissue repair (PubMed:28920588, PubMed:23348415).  Binding of gamma-delta TR complex to antigen triggers phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs) in the CD3 chains by the LCK and FYN kinases, allowing the recruitment, phosphorylation, and activation of ZAP70 that facilitates phosphorylation of the scaffolding proteins LCP2 and LAT.  This lead to the formation of a supramolecular signalosome that recruits the phospholipase PLCG1, resulting in calcium mobilization and ERK activation, ultimately leading to T cell expansion and differentiation into effector cells (PubMed:25674089).  Gamma-delta TRs are produced through somatic rearrangement of a limited repertoire of variable (V), diversity (D), and joining (J) genes.  The potential diversity of gamma-delta TRs is conferred by the unique ability to rearrange (D) genes in tandem and to utilize all three reading frames.  The combinatorial diversity is considerably increased by the sequence exonuclease trimming and random nucleotide (N) region additions which occur during the V-(D)-J rearrangements (PubMed:24387714).
What are the official names of this protein?
T cell receptor gamma constant 2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PUR7_PSEE4
Sequence: MEKRDELYRGKAKSVYKTDDADRLILLFRNDTSAFDGKRIEQLDRKGMVNNKFNAFIMQKLEEAGVPTQFDKLLGDNECLVKKLDMIPVECVVRNYAAGSLVKRLGVEEGIKLEPSTFELFLKNDEKGDPFINESHVVAFGWGTAEQLVEMKKLSLKVNEVLSKLFDDAGLLLVDFKLEFGVFHGQIVLGDEFSPDGCRLWDKETRKKMDKDRFRQGLGDVIEAYEEVAKRLGVPL
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: ACCA_BURP0
Sequence: MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEIERLSKKSQQLTKDLYANLTPWQVSQIARHPQRPYTLDYVSELFTDFHELHGDRAFADDQSIVGGLARFNGHACMVIGHQKGRDTKERAARNFGMPRPEGYRKAERLMRVAEKFGLPIFTFVDTPGAYPGVGAEERGQSEAIGHNLYVMAELKTPIIATVIGEGGSGGALAIAVADTVMMLQFSTYSVISPEGCASILWKSAAKAPEAAEALGLTAHRLKALGLIDKIVNEPLGGAHRDPKGMAALLRRALGDSLRQFQGMSVDALRERRFERLMAYGKFKETTPRA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_NEIGO
Sequence: MNLKNRHFLKLLDFTPEEITAYLDLAAELKDAKKAGREIQRMKGKNIALIFEKTSTRTRCAFEVAARDQGADRTYLEPSASQIGHKESIKDTARVLGRMYDAIEYRGFAQETVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLNQTAFAYVGDARYNMGNSLLILGAKLGMDVRIGAPQSLWPSEGIIAAAHAAAKETGAKITLTENAHEAVKGVGFIHTDVWVSMGEPKEVWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVTEEVFESPAGIVFDQAENRMHTIKAVMVAALGD
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEM5_CAEEL
Sequence: MEAVAEHDFQAGSPDELSFKRGNTLKVLNKDEDPHWYKAELDGNEGFIPSNYIRMTECNWYLGKITRNDAEVLLKKPTVRDGHFLVRQCESSPGEFSISVRFQDSVQHFKVLRDQNGKYYLWAVKFNSLNELVAYHRTASVSRTHTILLSDMNVETKFVQALFDFNPQESGELAFKRGDVITLINKDDPNWWEGQLNNRRGIFPSNYVCPYNSNKSNSNVAPGFNFGN
What is the function of this protein?
Adapter protein which modulates signaling mediated by several receptor tyrosine kinases such as egl-15 and let-23 probably acting upstream of let-60/ras.  Negatively regulates vulva induction probably downstream of let-23 (PubMed:1372395, PubMed:16547100).  Involved in sex myoblast migration (PubMed:1372395, PubMed:9073451).  Negatively regulates fluid homeostasis probably downstream of egl-15 (PubMed:1372395, PubMed:11689700).  During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles probably downstream of egl-15 (PubMed:16495308).  Involved in cytoskeleton dynamics and is recruited by mig-13 to the leading edge of Q neuroblasts and their descendants to signal downstream to activate the wsp-1 pathway and direct migration along the anteroposterior body axis during larval development (PubMed:27780040).  Involved in let-23-mediated regulation of fertility independently of let-60/Ras (PubMed:16547100).  Negatively regulates daf-2-mediated repression of dauer formation (PubMed:16547100).  Plays a role in nicotinic acetylcholine receptor (nAChR)-mediated sensitivity to nicotine (PubMed:15990870).  Regulates synaptic levels of nAchR subunit lev-1 in the nerve cord (PubMed:15990870).  May play a role in oocyte development upstream of let-60/Ras and the MAP kinase pathway (PubMed:12169634).
What are the official names of this protein?
Sex muscle abnormal protein 5.
What is the protein family that this protein belongs to?
Belongs to the GRB2/sem-5/DRK family.
What are the subcellular locations of this protein?
Cell membrane. Note=Targeted to the leading edge of Q neuroblasts by mig-13.
Protein: RNZ_THEVB
Sequence: MEITFLGTSSGVPTRTRNVSSVALRLPQRKEIWLFDCGEATQHQLLRSDLRTSQIRRIFITHMHGDHIFGLMGLLASCGLAGTVSQIDVYGPPTLDRYIASCLRWSVMRLPYKLQVHTVEPGEVFSDGEFTVTCRLLHHRVPAFGYRVTEGDRPGRFHVEKAQALGIPFGPLYGQLKQGKTITLEDGRTFDGRDFCDPPQRGRSMVYCTDTVFCDSAVELAQQADVLIHEATFSHQEANLAFARLHSTSTMAAQVAAFAQVKLLFLTHFSARYAPGNPVQVEDLLAEAQAIFPNTRLAQDFLHYAIPRDGQICAEMPPSDSPAAANIDTLEATLEPLEAQTVAADAKNAPAIAINRATRQQMQQKLGIDATTANAILERRRQQKFTCLGELERLYPQVDWSALNVLF
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity).
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: PURNU_RICCN
Sequence: MEGLINGSVYYKIFDKTFNNSSHRYIKKNNSINETEIVENKKSITTYFKAQDILILNQVHGNQIVNADESIIAVPEADGSITTKKNLILAVQSADCVPVLLASGDGKIIGAAHAGWKGSINNIISNIVTKITEKGAKNLIAVIGPAIAQSSYEVDDEYYKAFLSKDINNKQFFIHSIKENHYMFDLPAFVELKLKEAGVKDIKNIAEDTYTNPLKYPSKRRSYHLQEPYNQNILSAIVMK
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase RC0672, Adenosine deaminase RC0672, S-methyl-5'-thioadenosine phosphorylase RC0672.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: HOSA_PYRHO
Sequence: MILDSTLREGEQTPGVNYSPEQRLRIALALDEIGVDFIEVGHPAVSKDVFIGIKLIASQDLNANLLAHSRALLEDIDYVIQADVEWVGIFFCLSNACLRKRFRMSLSQALERISKAIEYAKDHGLKVRFTPEDTTRTEWENLRRAIELAKELKVDRISVADTTGGTHPLRFYTLVKKVVNFGIPVNVHCHNDLGLALANAIMGIEGGATVVDATVNGLGERAGIVDLAQIVTVLYYHYGVKKYRLDKLYEISRMVSEITGIALQPNYPIVGENAFTHKAGLHVSAVLKDPRFYEFLPAEVFGRERTIYVDRFAGKDTIRYYLQKLGINDEEFVKVLLKRVKSSREPFTWDKFIEEVRRLKT
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
Protein: Y3505_RHOP2
Sequence: MTAVPKKISPQDGFFWKTKTLEEMSQAEWESLCDGCARCCLEKLEDEDSGRIYFTHVGCRLLDGDACACHDYANRSERVPDCVRLTPENVRTLSWLPPSCGYRLVAEGRDLYWWHPLISGDPNTVHDAGVSVRGRVEATETEVSVEDLEDHIVSWPALLPRRAKLKKRPG
What are the official names of this protein?
UPF0260 protein RPB_3505.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: DER_CALS8
Sequence: MKPTVAIVGRPNVGKSTLFNRLIGERRAIVDDTPGITRDRIVGETEWRGITFNVIDTGGIEPYSEDIILKQMRRQAQFAIDMSDVIIFMVDGKTGLTDADREVANMLRVSKKPIVLAVNKIDNISEQPIIYEFYELGLSDPIPMSAEHGSGVGDVLDAVVSYFDKVGINEIEEDSIKVAIIGKPNTGKSSLVNYILGEERVIVSDIPGTTRDAIDSYVEFEGIPLTLIDTAGLRRKSKIYDNIERYSMLRTISAIERSDICVILLDGTEPVSEQDAKIAGYAYEAGKGCIIAVNKWDAVEKDEKTADEYKKQIEEKLSFLKFAPVLFISAKTGFRVKKLLETVLYVYGNYTRRITTGQINDVLAEATTIYQPPSDKGKQLKIYYMTQVGEKPPKMAIFVNDKDLFHFSYQRYIENYLRKTFDFTGVPIVFLIREKGEKD
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: UL24S_PSEXP
Sequence: MKLNLKASGVARQLTTLAKTVAALSVLTACASSNTATVSSAMSKANGVFLESQTKITNGALHFDGKKLNHNTFEKPSLGPEYDYFFGKNISAHGDAVKPYKHYVFMTWYKGGKEQRNVMLSRFNTKTGVVKTIQFPHRHTGFRGNPLVGESHNTIGLAVSPKNGTIHMVYDMHAYVDDDESGRFKGRFVDDFFRYSFSVPGAADVPDDEFTLEKFVKDTSEVSQGTDDFKHLTMTGNLEDKDNFSALTYPKFYKSKEGELLHYMRWGGNNNGAYYFNKYDAEKQVWTRFTPFNHKDQETHGNAYNWGLYGQMKYINGKLRVGFQQRSANNNDRYKYQNGVYYAYSDHPDGLGDWKNVDGENMTWPLVDSDEIKIFEPGDYIDHQEPNSVHIVGGFDWTVTENEDLHFITHVRSTNTKRSDYKEVSIHAFKPANAKDFTVTTDFTGADSIYTSGDSIFIIGLKNGYPFVEKAKGGTNEFEVVYQQTSGVKFDHGTIHIENGKAYYYLMEKGAGNSLPLHLQVIDLGVSR
What is the function of this protein?
Ulvan lyase involved in ulvan degradation.  Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall.  It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl).  Ulvan lyase catalyzes preferentially the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acid GlcA, but not IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end.  The most abundant end products in the degradation of the ulvan polysaccharide were deltaUA-Rha3S disaccharides and deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides.
What are the official names of this protein?
Ulvan lyase, short isoform, PsPL.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 24 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: ASIC1_HUMAN
Sequence: MELKAEEEEVGGVQPVSIQAFASSSTLHGLAHIFSYERLSLKRALWALCFLGSLAVLLCVCTERVQYYFHYHHVTKLDEVAASQLTFPAVTLCNLNEFRFSQVSKNDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDRAGHDIRDMLLSCHFRGEVCSAEDFKVVFTRYGKCYTFNSGRDGRPRLKTMKGGTGNGLEIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVACQEQRLIYLPPPWGTCKAVTMDSDLDFFDSYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKECADPALDFLVEKDQEYCVCEMPCNLTRYGKELSMVKIPSKASAKYLAKKFNKSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTVLELFDYAYEVIKHKLCRRGKCQKEAKRSSADKGVALSLDDVKRHNPCESLRGHPAGMTYAANILPHHPARGTFEDFTC
What is the function of this protein?
Isoform 1 does not display proton-gated cation channel activity.
What are the official names of this protein?
Acid-sensing ion channel 1, ASIC1, Amiloride-sensitive cation channel 2, neuronal, Brain sodium channel 2, BNaC2.
What is the protein family that this protein belongs to?
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity).
Protein: BRXL5_ORYSJ
Sequence: MHVCFHGGGGGGGGRLAKSFNVISDFTKILIGRRGGDHALARRRRMRQCKDAAPAAAAAAVASASAKIAPEEEGEGGGGGKEEEFCDKCCSALSGGGGAEEEAAAEGEREWVAEPEPGVLLTLAPRADGVSNRLRRIRFREEVFDAWAAQCWWADNHDRIAELYCLVKPDDDDDEEEAIAAAEAAMLPATPCQSEAEDDDDDDGAESSSRSPSTSTFSGGPSSGSGGGSTGTLGSPILGLVTAPNTTGGGEHDAVRDQHQPTAATWREWVEEYEPGVFITVGAYPGHRLQLRCVELSREKFGEVKARVWWEENKARLHHLYSF
What are the official names of this protein?
Putative protein Brevis radix-like 5, OsBRXL5.
What is the protein family that this protein belongs to?
Belongs to the BRX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EI2BE_DICDI
Sequence: MSKNDKKNKQSGSSNMDQLKSEDILQAVVLGDSFDRKFAPITLEKPRTLLPLVNIPLLDYTLEFLAASGVQQIFVFCCAHASQIKEYIQSSRWHDLPGVQVICMTGSNCRTTGDALRGVYDAQVIQSDFILISGDVVSNMNLQKALQIHKDRRELDKNNIMTMVYKQASSTHRTRSKQDDTVIWCNRDTMQVVCYDNSPSKKKSSISVELFQKHPSIQMRYDLIDCHIDICSPEVLALFNDNFDFADIRKDFIHDILTSDLLDYKLSAYVLQGEYAARVKDLRTYHSVSKDIIHRWTFPMVPDNNFMCNSSYSLSRQMIYKEKNVKLLGDCLISDETVIGTQTEIGAGSIVSHSTIGRNCIIGKNVKINGSYIWDDVTIQDNAIIDHSIICNGSIIKSSSIIGRGSIIGFNVYIGQSKTLEPFSKITMAQYNEDEDDEELLEEYFKEINLNDDNNNNNNNNNENNKTNRWLMENELYNELVPRINDSIHDDIESDESGDEGDKSGGKIKNNKNNDDNPIEPDSVKFHREVGDTIRRGIIEKLPLENIQLEINGLKFAYDRDGLDCLTSILPVLLESSSSSSSTTDSVTPKELQQFIAGRISAFSPLLVKFSSEDSMVDLIFKIQDFCDENEKFKVVFQPILHQLYENDVISEEAIFEWAEEIEGDEEDDGFYLKKCKGFIDWLKSAEEESDDSDDSDDDDDDSDESD
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit epsilon, eIF-2B GDP-GTP exchange factor subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B gamma/epsilon subunits family.
Protein: GRCR1_DROME
Sequence: MVLATPPVSKGGNAGGLFMDQYQQYAAHCETADSGNGSDLESTGLPTKPDDSEESGPSSLGSDSMHGSSTEYVRQSASQPSGQRQRQKSLRVLGALLPDSLLRDIRDRRSTEYVVQFSQPEDEEKIQVPDKIPEKPSPFRLARESLSEDKIEELRAAVERANFVQTGEETLDSIDATSQSLPASSNIGGHRGNINYKYADDQYYSFHINEHENFGARSARSGDEADHSTGAGSEAGSDSGILTEQQDLFAGYRDVRCGASSTQSTIRSAKGTVRGVKNRVRNGIATFLQLQQQPNAKNFKEKDLGKVVLYTTSMGIIRETYTKCANVKQILRTLLVKFEERDVFMSVEYQAEMRQRMQSGQVRVPQLYVEGQHIGDAETVERMNESGELRQLLKPYKSMASTYTCQTCGGYRLLPCPSCNGSKKSVHRNHFTAEFVALKCMNCDEVGLVKCHNC
What are the official names of this protein?
Glutaredoxin domain-containing cysteine-rich protein CG31559.
What is the protein family that this protein belongs to?
Belongs to the GRXCR1 family.
Protein: ACTN3_MOUSE
Sequence: MMMVMQPEGLGAGEGPFSGGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIINYKSNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQLNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVEFARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGSGAPSGALDYVAFSSALYGESDL
What is the function of this protein?
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures.  This is a bundling protein (By similarity).
What are the official names of this protein?
Alpha-actinin-3, Alpha-actinin skeletal muscle isoform 3, F-actin cross-linking protein.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.