PharMolix/UniProtQA huggingface dataset:
Protein: RESA_BACCR
Sequence: MKKNRLLFRVIILLILCGAVGFTLYQGFFANKEKMQIGKEAPNFIVTDLEGKKIELKDLKGKGVFLNFWGTWCKPCEKEMPYMNELYPKYKEKGVEIIALDADETDIAVKNFVNQYGLKFPVAIDKGQKIIGTYGVGPLPTSFLIDKDGKVVEQIIGEQTKEQLEGYLKKITP
What is the function of this protein?
Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis.  May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalently attached.
What are the official names of this protein?
Thiol-disulfide oxidoreductase ResA.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. ResA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane.
Protein: YPEB_ECO57
Sequence: MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAGKLGELMQITLLIKTEGLTQLVQPLKRPL
What are the official names of this protein?
Uncharacterized protein YpeB.
Protein: RIBU_LACLM
Sequence: MSKTRRMVLIAMLAALSTILLLPILQFPLLPGIDFMKVELSIIPVLIGVFTLGLGDGFIILFIRSVLWYLLFNQGPSTWIGVPMNFVALGIFMAIVWFFTKKKFSIKNYTVGIVLATIASVLVMMVLNVFYALPLYRLAAGFDVDKIFAGATHLFNMGSLSVTLNPTYLLTVVLPFNALQYIIFALVFGLIVTVFKKNKVVKFYNA
What is the function of this protein?
Mediates riboflavin uptake, may also transport FMN and roseoflavin (By similarity).  Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.  The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins.  Uptake of riboflavin into proteosomes containing EcfA1A2T and RibU has been demonstrated.  Uptake requires hydrolyzable Mg-ATP.
What are the official names of this protein?
Riboflavin transporter RibU, Riboflavin ECF transporter S component RibU.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBT_TAXBR
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPDRGGK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: Y112_MYCPN
Sequence: MLDKLLQKFRDQKKPVFHKEEGYWEISALRKWAAILIIAFGAGIIYIVPYFAFFQFKTAVANVTGVEPNRISLLLTAYGIVSLLFYIPGGWLADRISAKALFSVSMFGTGIITFWYFLVGLKGIVWITPN
What are the official names of this protein?
Uncharacterized protein MPN_112.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHNS_SOLFR
Sequence: MNFSVGLGRDDAEKRLVQNGVSRRDFMKFCATVAAAMGMGPAFAPKVAEALTAKHRPSVVWLHNAECTGCTEAAIRTIKPYIDALILDTISLDYQETIMAAAGEAAEAALHQALEGKDGYYLVVEGGLPTIDGGQWGMVAGHPMIETTKKAAAKAKGIICIGTCSAYGGVQKAKPNPSQAKGVSEALGVKTINIPGCPPNPINFVGAVVHVLTKGIPDLDENGRPKLFYGELVHDNCPRLPHFEASEFAPSFDSEEAKKGFCLYELGCKGPVTYNNCPKVLFNQVNWPVQAGHPCLGCSEPDFWDTMTPFYEQG
What is the function of this protein?
Involved in hydrogen uptake for the anaerobic reduction of sulfate to hydrogen sulfide in an electron transport chain.  Cytochrome c3 is the physiological electron acceptor.
What are the official names of this protein?
Periplasmic [NiFe] hydrogenase small subunit, NiFe hydrogenlyase small chain.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Periplasm.
Protein: GRT1_SCHPO
Sequence: MVLSKRPVRISKACENCRKRKVKCSGGDVCFECQKYNENCVYRQFYRKIKRLKYNNDNSKIDNFSNEQMNIPEFISVRNLNDDSSSIEFFGPASNISFVNQLNHYLRKAERNGYDFLSEGQNDITPEEERKGLEKFGMKLMVLKDNANNFDFSLSNITTEKMNGLLIAYLETWHIPCPIFKAEDLFNLSVRTWKNPSASVHDKALLYLILSIGSAASYFDLQSNSSTLPLARGFFNLALRTVPHIFTELSLDAIRIVFFMSVSAGNLGDTALSYLYSGTAVRMSLAIGLHKCKNFSNDLSDKYQNIRLWVSVWQWEGYWSFCVGRPSCSRQDIPIPAVPNEAFSFSGYGEHGRFLINHEHMRLRVFFSSCCSKIQSEIYSTNRNLLSVLQTVEQISKEVDKEYFSSTNHQLIRSEIGEYCKTLDINSCREWFWIRIYYLYLKLMIFRPFLIFLAYVNISKTSAPDDIIEGLKRGSDQCVQEAIDISKFIVQLNRKVRMLQPIFFICTYLESACTVLLFYIASNSAKIQGQLATEIWAVLRDTCSFLQGSSGPYVGSVSTIAKDALESLNNILVSKKYQDNSVNNTYFDKVMQHVLVHSPAFDDSSDPKFETNRSETPTQYTLDDSANDELMIPDLQGFWEQTLDWINN
What is the function of this protein?
May be involved in the facilitation of anaphase progression in mitosis.
What are the official names of this protein?
Zinc finger protein grt1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_HELHP
Sequence: MPTINQLIRKERKKVIRKTKSPALLECPQRRGVCTRVYTTTPKKPNSALRKVAKVKLTSKVEVISYIPGEGHNLQEHSIVLVRGGRVKDLPGVKYHIIRGALDTAGVAKRNVSRSKYGAKKAKAGGDKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RPOB_ECOLI
Sequence: MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
What is the function of this protein?
Part of the processive rRNA transcription and antitermination complex (rrnTAC).  The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNAP.  It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NUSA_MYCGE
Sequence: MKITFISGQEVSLGTSFLLFSKKIVMNELNQPLLAIIKNVAKTKNLSIEEVVFCLKTALEQAYKKHLNFVNVEVNINFDKGIINVEQLFNVVSDENEDYDDFLEIPLQAANKINSSLQLGDVLRKPIPLKNISSDLINKMIAIFNQKISETNFKAVMSEFSSEVGEVIEAKVEDIDTNKEGGLKGYIINLETTKGYISKRELSKGERLEIGKKYLFVIKEIQRQASLWPITLSRSDTRLLQFLLTSNTPEIENGTIVIKKIERSPGVKSKIAVISNDPAVDPVAAILGPKGEKIRGISEEFNGEIIDIVFWNEDKLKFLINAILPAEVIGYNILQDDERDTSIEVVVPANQIANVFGFKGVNIRLISNLTGWNSVDVYSEKDASEANIKFTRLSFEPEGLFGIKKRREKIISNDATDKVFYTSKDNVIDDEIIVDLAKDLMVDNKQKQPEQVAKQVVEKSQLEKQVTPKEKEKVQPKAKVHSNSHSKKPAKPNQIFSITVDASDKNLKKDQVDNNQTNPQTKQTFDSFDDL
What is the function of this protein?
Participates in both transcription termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusA.
What is the protein family that this protein belongs to?
Belongs to the NusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_OLEA2
Sequence: MPTINQLIRKERKKVAKRKKTPALQACPQRRGVCTRVYTTTPKKPNSALRKVARVRLTNAIEVTAYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIVRGTLDTAGVQDRRQGRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: BORC8_DICDI
Sequence: MSSILKSSTGSNHSSTSNHSSINNISQLSGSHGVEQQQLRPVLTLDASTAKLMYQTSQEMSSYIQQVANEPTIGLFHVQDHIRRNIPKNVELKKNIKALGEKIEEKSFDIDYSTKTIKTFSEIQTFSNISSLLQQSIERANKLVNNKSLLFVNSQMAAPSSSKTFSSFQQQHKIYQQQQTNLTPSKPTLSNDKTNDNNNNNNNLNFVEKIEKEEKIEKEDEGKEKDEKEKDDKDLNEKIN
What is the function of this protein?
May participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor.
What are the official names of this protein?
BLOC-1-related complex subunit 8 homolog.
What is the protein family that this protein belongs to?
Belongs to the BORCS8 family.
What are the subcellular locations of this protein?
Lysosome membrane.
Protein: GG12J_HUMAN
Sequence: MSWRGRSTYYWPRPRPYVQPPEMIGPMRPEQFSDEVEPATPEEGEPATQRQDPAAAQEGEDEGASAGQGPKPEADSQEQGHPQTGCECEDGPDGQEMDPPNPEEVKTPEEGKKQSQC
What are the official names of this protein?
G antigen 12J, GAGE-12J.
What is the protein family that this protein belongs to?
Belongs to the GAGE family.
Protein: UBIG_METNO
Sequence: MSETTGPSIDRDEVARFERIAATWWDEAGPMRVLHRFNPVRITYIRDTVCRHFGRDPRRPLPLEALSLIDIGCGGGILSEPLARLGATVTGLDPAPTNIRVAQAHAAEAGVPVDYRGQTIEAVVEAGERFDVVLAMEVVEHVVDMPAFVRTACAAVKPGGLFFAATLNRTMRSFALAIVGAEYVLGWLPRGTHDWEKFVTPAELTGAVESAGLTVIDTTGVVYNPLGGRWAMSRDTGVNYMIAAERPVA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: NOS2_ONCMY
Sequence: GWYMGTEIGVRDFCDYQRYNILEEVGRRMGLETHKLSSLWKDQALVTINVAVTYSFQKNKVIITDHHSAAESFMKHLETEFPPARRLPADWDWLVPPMSGSLTPIFHQEMVNYILSPFFYYQPDPWMTHVWRNGEMCLKKQQISFKAVARAALFSSTLMSRVLANRVRCTVLYATETGKSQTLAQRLNSMLNCAFNSRLLCMEDYNFSDMEQESLLVVVMSTFGNGGSPGNGESFKKQLFSLQYLRNKSRYCVFGLGSRMYPQFCAFAHAVDAKLEELGAERVTPTGEGDELNGQEEAFSAWALTALKDAYKEFKIQGQLSLQLPGAERFCEAWDPLRHRVAVESCPQDRITALSAIHSKAVLPMKLKSKHNLQSPQSSRSTILVELERERSPEVMDFAPGDHVGVFPGNLPQLVAGILKFLPQTPPTNQCLRLGYRSDTFRVMRKTGRLLDASQHSLCLRHSPTSWTLP
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.  In macrophages, NO mediates tumoricidal and bactericidal actions.  Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2 (By similarity).
What are the official names of this protein?
Nitric oxide synthase, inducible, Inducible NO synthase, Inducible NOS, iNOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CSEC_STRCO
Sequence: MRGFFRQRRSVSPPGHPYDRTGPGEHAGPGARTGPGGRPRVLGVRGLRARGIRTGLRWKLSAAIALVGALVAIALSLVVHNAARVSMLDNARDLADDRVLIAQRNYELSGRQNFPNAQIDDPALPPELRRKIDAGRRATYVSERPDGVTDIWAAVPLKDGHVMSLHSGFTDRSADILSDLDQALVIGSIAVVLGGSALGVLIGGQLSRRLREAAAAANRVASGEPDVRVRDAIGGVVRDETDDVARAVDAMADALQQRIEAERRVTADIAHELRTPVTGLLTAAELLPPGRPTELVLDRAKAMRTLVEDVLEVARLDGASERAELQDIMLGDFVSRRVAAKDPAVEVRVIHESEVTTDPRRLERVLFNLLANAARHGRSPVEVSVEGRVIRVRDHGPGFPEDLLAEGPSRFRTGSTDRAGRGHGLGLTIAAGQARVLGARLTFRNVRPAGAPAHIPAEGAVAVLWLPEHAPTNTGSYPMLPDRSKSGASSSARDMSREASQGMSRKP
What is the function of this protein?
Member of the two-component regulatory system CseB/CseC involved in the stability of the cell envelope, through activation of transcription of RNA polymerase sigma-E factor.  CseC functions as a membrane-associated protein kinase that phosphorylates CseB in response to changes in the cell envelope.
What are the official names of this protein?
Sensor protein CseC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NEU3_EPTST
Sequence: MSAMGWTLLAAALLAISAQSNGCYIQNCPRGGKRAVETELHSCAACGLGGQCVGPSICCGGLLGGGRGGGCIVGGPLSAPCKRENLHPEPCRPGGGSSCGLEGICAAPGICCTDVTCSIDATCDDVTEKAGVTFSGATGGLANPTGDLLRKVLLLANADLE
What is the function of this protein?
Vasotocin is an antidiuretic hormone.
What are the official names of this protein?
Vasotocin-neurophysin VT.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRS4_RAT
Sequence: MGQSQSGGHGPGGGKKDDKDKKKKYEPPVPTRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC1 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 4, P26s4, 26S proteasome AAA-ATPase subunit RPT2, Proteasome 26S subunit ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Membrane; Lipid-anchor.
Protein: ARAB_SALPA
Sequence: MAIAIGLDFGSDSVRALAVDCATGDEIATSVEWYPRWQEGRYCDGPNNQFRHHPRDYMESMEAALKAVLAQLSAAQRANVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEADEITRLCHKPGKVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQAAVSWIELCDWVPALLSGTTRPQDIRRGRCSAGHKTLWHESWGGLPPASFFDELDPCINRHLRYPLFSETFTADLPVGTLCAEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNTLVKVIGTSTCDILIADKQSVGDRAVKGICGQVDGSVVPNFIGLEAGQSAFGDIYAWFSRVLSWPLEQLAAQHPELKTQINASQKQLLPALTDAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPALFGGLVASTAFGARAIQECFTEQGIAVNNVMALGGIARKNQVIMQVCCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPAAQQSMASAVERTLRPRPEQAQRFERLYRRYQQWALSAEQHYLPTAAPAPTTPANQAILTH
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: TRUB_BORA1
Sequence: MAKRRGQPLDGVLLLDKPVGLSSNHALQRAKRTLDAAKAGHTGTLDPFATGLLLCCMGRATKISGAMLNADKTYRATLQFGEETDSGDLTGNIVARAPEDFPGVEEANLREVLSRFQGSIEQIPPMYSALKRDGKPLYEYARAGIELERPPRRVMIYRIELLSFTGHQAEIDVACSKGTYIRTLAQDIGRALGCYAHLFALRRTQVGPFSLDRAVTLDALQAMTDPKAALLALNELPAGLLPAT
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MEND_VIBCH
Sequence: MNRDQALLNRLWSRVLLEELSRLGVTQVCVAPGSRSTPLTLEANANTAFTLHTHYDERGLGFMALGLAKASQQPVAVIVTSGTAVANLLPAIAESKLTGERLVVLTADRPLELVGCGANQAIVQSGIFSSHVTASLELPSPAIHHPLSWLLTSIDEVMARQALLGGSVHINCPFPEPLYSAGDEAIYQPYLQPVQRWREQARPYTQVHQGLVQSVPAAIDGLLTKGVVIVGSLSLQEAQAAKRFAKAMGWPLLCDPQSGISSQWAHFDLWLQHPKAREQLNQAQCVVQFGSRIVSKRLLQWLEAWCATGLGEYHYIAPHSARNNPWHAMQQQWVCEISHWVDAVLSKRLAGQHTQQGWADELTHYAQSVRQLAQLHFSSSSLSEVALALDLTERATQADLFLGNSLIVRLVDIFSALDGREVFSNRGASGIDGLVATASGVQRARQKPLLMLLGDTSLLYDLNSLALMRNPAQPTVIVVTNNDGGAIFDLLPVPSEQREALYQMPHGMDFAHAASQFGLAYCAAQTLEHYQTLVEEHFAHGAGTLLIEVKTPPQQASMHIKQLTSQLHAL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: WBC30_ARATH
Sequence: MRVRVDVCWTQHIFLFFVFGLSFMSFALSLDGDDYSKTGNPKALVSVTNLIYTRLQNLKTVLKADVDRDLGYCIKNLKGDWNEAFNFDKNLDFLSNCVKKNDGDLTLRLCSAAEIKFYFSSFVRRDEATTVHVKPNINCNLAKWVSGCEPGWSCNADDEKRFDLNNGKILPSRTRKCQPCCEGFFCPQGLACMIPCPLGAYCPLAKLNKTTGFCEPYNYQIPPGKLNHTCGSADSWVDAESSGDMFCSPGSYCPTTIRKVTCSSGHYCRQGSTSQKPCFKLATCNPNTANQNIHAYGAILIASLSLLMIMVYNCSDQVLATREKRQAKSREAAARHAKETTQARERWKTAKGVAKNQKMGLSAQLSQTFSRMKSARKDATPVKASGKSKDKKKEPSNLTKMMKSMEENPSNNEGFNVGTGSKPGKKPQAPKGKQLHTQSQIFKYAYGQIEKEKAMEQNNKNLTFSGVISMATDTEMRTRPVIEVAFKDLTLTLKGKHKHILRSVTGKIMPGRVSAVMGPSGAGKTTFLSALAGKATGCTRTGLILINGRNDSINSYKKITGFVPQDDVVHGNLTVEENLRFSARCRLSAYMSKADKVLIIERVIESLGLQHVRDSLVGTIEKRGISGGQRKRVNVGVEMVMEPSLLILDEPTTGLDSASSQLLLRALRREALEGVNICMVVHQPSYTMYKMFDDMIILAKGGLTVYHGSVKKIEEYFADIGITVPDRVNPPDHYIDILEGIVKPDGDITIEQLPVRWMLHNGYPVPHDMLKFCDGLPSSSTGSAQEDSTHNSFSNDLWQDVKTNVEITKDQLQHNYSNSHDNSNRVTPTVGRQYRYFVGRVGKQRLREARLQALDFLILLVAGACLGTLAKVNDETIDTLGYTYTIIAVSLLCKISALRSFSVDKLQYWRESAAGISSLAHFMAKDTMDHLNTIMKPLVYLSMFYFFNNPRSSFEDNYIVLVCLVYCVTGMAYIFAILYSPSAAQLLSVLVPVVMTLIANQDKESMVLKYLGSFCYPKWTLEAFVLSNAQRYSGVWVVTRCSSLSQNGYDLSDWILCLIVLVLMGLICRFIAYFCMVTFQKK
What are the official names of this protein?
Putative white-brown complex homolog protein 30, Putative non-intrinsic ABC protein 12, WBC-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YFIA_ECO57
Sequence: MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKEPQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVKDANFVEEVEEE
What is the function of this protein?
During stationary phase, prevents 70S dimer formation, probably in order to regulate translation efficiency during transition between the exponential and the stationary phases.  In addition, during environmental stress such as cold shock or excessive cell density at stationary phase, stabilizes the 70S ribosome against dissociation, inhibits translation initiation and increase translation accuracy.  When normal growth conditions are restored, is quickly released from the ribosome (By similarity).
What are the official names of this protein?
Ribosome-associated factor Y, pY, Ribosome associated inhibitor A.
What is the protein family that this protein belongs to?
Belongs to the HPF/YfiA ribosome-associated protein family. YfiA subfamily.
Protein: RL5_XYLFA
Sequence: MTRLENMYKKEVVPALIKRFGYSNPMAVPRLVKITLNMGVGEAATNKKVLENAVADMAKISGQRPIVTKSRISVASFKIRNGWPIGCKTTLRRSKMYEFLDRLINISLPCVRDFRGIPPRSFDGRGNFNMGVKEQVVFPEIDFDAVDAIRGMDIAITTTANSDAEAKALLDAFNFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y02D_BPT4
Sequence: MKIAILVIALGLAGCVAQGPVVNQSDVGKIVNCSSKFYNPNVKCYKEAPKQTVEQMQANFDEAIRPDESAQAYRNSDVITREEKIENYCAELWANWANNYQWRTGKNAPMEYVVNSYNSCVKNLT
What are the official names of this protein?
Uncharacterized 14.1 kDa protein in imm-Gp43 intergenic region.
Protein: RL2_SHEB8
Sequence: MAVIKCKPTSPGRRHVVKVVNTDLHKGKPFAGLLAKKSKSGGRNNTGRITVRHVGGGHKQHYRLIDFKRDKDGIPAKIERLEYDPNRTANIALVLYADGERRYILAAKGMQAGDKIQSGVAAEIKTGNAMPLRNIPVGSVVHAVEMKPGKGAQIARSAGAYVQVVARDGAYATLRLRSGEMRKVPVDCRATFGEVGNAEHMLRQLGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGVPTKGYKTRSNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PSAC_THEVB
Sequence: MAHTVKIYDTCIGCTQCVRACPTDVLEMVPWDGCKAGQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGAETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PM1A_HOMSP
Sequence: YCQKFLWTCDSERPCCEGLVCRLWCKIN
What is the function of this protein?
Potent and selective inhibitor of Nav1. 7/SCN9A sodium channels.  Inhibits Nav1. 7/SCN9A peak current (IC(50)=13 nM) (PubMed:31647222).  In vivo, does not induce visible signs of toxicity when intravenously injected into mice (PubMed:31647222).
What are the official names of this protein?
Mu-theraphotoxin-Hsp1a, Hsp1a, Mu-TRTX-Hsp1a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.