PharMolix/UniProtQA huggingface dataset:
Protein: YDDR_BACSU
Sequence: MNITQIRNATIVVKYANKKFLIDPMLAEKGTYATFPETIRQDLFNPLVSLPTSIDNILDGVDAVIVTHLHLDHFDDVAKNVLPKNIKMFVQNEADAKEVKASGFKNVEVLHQDTVFEGIQLVKTKGEHGRGEELLNLMGDVCGLVFKHPSEKVLYVAGDTVWYDAIEDEIHTHQPEIIVVNGGDNQRLDLGSLIMGKEDIYEVHKAAPHAKIISVHMEAVNHWTLSREELKNFSKEKGFSSNILVPEDGESYTF
What are the official names of this protein?
UPF0173 protein YddR.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: METAS_VIBVY
Sequence: MPIRIPDQLPAADVLRTENIFVMSETRAAKQEIRPLRVLILNLMPKKIETETQFLRLLSNSPLQVNVELLRIDDRPSKNTPTEHLDNFYRQFEMVKNRNFDGLIITGAPLGLVQFEDVIYWDHLKTIMEWAKSHVTSTLYVCWAAQAGLKLLYDLPKKTRKEKLSGVYHHRIHKPYHPVLRGFDDSFLAPHSRYADFSPEYLAEHTDLDILATSDDAGVYLATTKDKRNVFVTGHPEYDPHTLHNEYIRDLGEGMEPAIPVNYYPNDNPDNPPIASWRSHGHLLFSNWLNYCVYQQTPYDLDHFSEEAFTKDE
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE7_HPV17
Sequence: MIGKEATIPDIVLELQQLVQPTDLHCYEELSEEETETEEEPRRIPYKIVAPCCFCGSKLRLIVLATHAGIRSQEELLLGEVQLVCPNCREKLRHD
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: TYSY_STRZJ
Sequence: MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAFSEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDTGTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMFDVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNLHIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_HERA2
Sequence: MARLKDVYLKTVAPALFKDFGFKSPMQVPRITKIVINIGLGEALQNPKAVEAAIGDLTMIAGQKPVVTRAKKSLAAFKLRQGMPIGAMVTLRNDRMYDFYDRLVNLALPRIRDFQGLSRKSFDGRGNYSIGIREQIIFPEIEYDKVDKIRGLEVAIVTTAPNDEQGFALLKALGMPFRD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: UBID_ALBFT
Sequence: MAYRDLRDFITQLEHLGELKRVQAEVSPYLEMTALCDRTLRAGGPALLFENPTGHNTPVLGNLFGTTRRVALGMGVNDVSELRQFGHVLASLKEPEAPKGFKELMGLGSLVKTLWAMAPKELRSAPCQEIIWEGADVDLARLPIQHCWPGDVAPLITWGLVITQGPHKARQNLGIYRQQVLARNKVIMRWLAQRGGALDFKEHAALNPGQPYPVCVALGADPATILGAVTPVPDSLSEYQFAGLLRGSRTELVKALGSELRVPAFAEIVLEGHIYPDATHASGFEHALEGPFGDHTGYYNEQDWFPVFTIDRITQRRDPIYHSTYTGKPPDEPAMLALALNELFVPLLQRQYPEITDFYLPPEGCSYRLAVVQIKKSYPGHARRVMFGIWSFLRQFMYTKFIVVVDDDVNIRDWKDVIWAITTRVDPTRDTLLADSTPIDYLDFASPVSGLGSKMGLDATNKWPGETSREWGRPLTMSADVTARVEQVWQTLGL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MT54_BRANA
Sequence: MAGSNCGCGSGCKCGDSCSCEKNYNTECDSCSCGSNCSCGDSCSC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein-like protein LSC54.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: CSM6A_STRTR
Sequence: MKILISAVGTTDPISNNHDAALLHIARNYRPDKIVLVYSQEMMVKQDLINKVLLSIEGYNPIIEIDSTILNNDEVFLFDKMYEVMGQIVQKYTNDDNEIILNLSSGTPQIISALFALNRINDYNTQAIQVATPKNRANREYTALTESEIDALIMENQDNRLDFVDRSIKDKSEKFTQALVKRHLRSLIASFDYQAAEAIINRKEYNKLLSKKKIAYIREKLYDFSRVFKNQSILSDILSFPLDDSQKKALNYYLMIDVLKEREHIADVLIKAKSLAEFVIEETIKKDHEGLIVFDGNLPKLNPSFPDCEAILDDIDKKMKKSRGIEDTEERIFSVQSTLNLLSYLNILEFYEYDSQLQTAINGILSLNGERNKVAHGLSEIDTRLLSRKKLKQLSENLRLLLVDCLGIDSSYFNYYDKQNKELIKMLE
What is the function of this protein?
A single-strand-specific endoribonuclease (ssRNase) that is approximately 1000-fold stimulated by cyclic oligoadenylate (cOA); although several species of cOA are synthesized by this organism only cyclic hexaadenylate (cA6) stimulates the ssRNase activity.  Cleaves preferentially within GA or AA dinucleotides, although the presence of cA6 broadens the preference.  Linear oligoadenylates do not activate the RNase.
What are the official names of this protein?
CRISPR system endoribonuclease Csm6, CRISPR type III-A associated protein Csm6-1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm6 family.
Protein: KDSB_YERPG
Sequence: MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATIPWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDLDRVRAIMLNQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAF41_CAEEL
Sequence: MAKQPTVLWAQRESLVYLTIEVDEAKIEELKGEGNKLHFQGSSKTDKYEATLEFFDEIDPASVKHTGSSTRVVEITVQKKTPAWWPRLLQNKGKVHWLKVDFGKWKDEDEDDEAEDAGAGIGGGMANGFDLNQYMSQMGGAGGADFGGLEDDEEDDDMPDLEDNEEEEGKNGTRA
What is the function of this protein?
Co-chaperone for hsp90/daf-21 (PubMed:20880838).  Involved in regulation of longevity, larval entry and exit from the dauer stage of development and response to environmental cues, such as oxidative stress, in a temperature-dependent manner.  Role in daf-16 and hsf-1 inhibition at elevated temperatures (PubMed:25830239).
What are the official names of this protein?
Co-chaperone protein daf-41, Abnormal dauer formation protein daf-41, p23/cytosolic prostaglandin E synthase 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the p23/wos2 family.
Protein: ATPG_ROSS1
Sequence: MPSTREIRRRIRSVKNLAQITRAMEMVSASKMRRAQRNVLATRPYADRLLDVMGELTGRAVGMRRGTLLEVRPVVQGVALIVVTPDRGLAGSLVANVLRRASRFILDEQEKKHTVEVLAIGKKGRDFMVRTHQNLVAEVTKLGDHPRLTDILGISTHVINGFLGGRYDEVYVLYSQFVNTLVQRPTIKRLLPIDPPHEPAERMVDYTYEPSQEEVLRELLPRFVEVQLYQAVLEAIASEHSARMVAMRNATDNAKELQRDLTLSYNKTRQANITKEVSEIASGAAALAEM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NUOCD_ECOL6
Sequence: MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMVEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SODC5_DICDI
Sequence: MSAICVIKGDGVDGIINFKQNDNKSPVIISGVISGLKEGKHGFHVHEFGDTTNGCLSAGAHFNPFKKEHGSPNDENRHVGDLGNIESNKDKKSIINITDNIITLFGQNSIIGRSIVVHDKEDDLGRGNSQDSKITGNAGSRLGCGIIALSKI
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn] 5.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
Protein: GLMM_STAAM
Sequence: MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ATLA1_MOUSE
Sequence: MAKSRRDRNSWGGFSEKSSDWSSEEEEPVRKAGPVQVLIVKDDHSFELDEAALNRILLSQAVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWVGDYNEPLTGFSWRGGSERETTGIQIWSEVFLINKLDGKKVAVLLMDTQGTFDSQSTLRDSATVFALSTMISSIQVYNLSQNVQEDDLQHLQLFTEYGRLAMEETFLKPFQSLIFLVRDWSFPYEFSYGADGGAKFLEKRLKVSGNQHEELQNVRKHIHSCFTNISCFLLPHPGLKVATNPNFDGKLKEIDDEFIKNLKILIPWLLSPERLDIKEINGNKITCRGLLEYFKAYIKIYQGEELPHPKSMLQATAEANNLAAVATAKDTYNKKMEEVCGGDKPFLAPNDLQSKHLQLKEESVKLFRGVKKMGGEEFSRRYLQQLESEIDELYIQYIKHNDSKNIFHAARTPATLFVVIFITYVIAGVTGFIGLDIIASLCNMIMGLTLITLCTWAYIRYSGEYRELGAVIDQVAAALWDQGSTNEALYKLYSAAATHRHLCHQAFPAPKSEPTQQPEKKKI
What is the function of this protein?
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes.  Functions in endoplasmic reticulum tubular network biogenesis.  May also regulate Golgi biogenesis.  May regulate axonal development.
What are the official names of this protein?
Atlastin-1, Spastic paraplegia 3A homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, axon. Note=Localizes to endoplasmic reticulum tubular network.
Protein: RL7_STAAS
Sequence: MANHEQIIEAIKEMSVLELNDLVKAIEEEFGVTAAAPVAVAGAAGGADAAAEKTEFDVELTSAGSSKIKVVKAVKEATGLGLKDAKELVDGAPKVIKEALPKEEAEKLKEQLEEVGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RBL_LUPAE
Sequence: SVGFKAGVKDYKLTYYTPDYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNQIIREASKWSPELAAACEVWKE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PCDG3_HUMAN
Sequence: MTNCLSFRNGRGLALLCALLGTLCETGSGQIRYSVSEELDKGSFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSLDREQISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLRRWHKSRLLQASGGGLASTPGSHFVGADGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLISQESCEKSEPLLITQDLLEMKGDSNLLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-A3, PCDH-gamma-A3.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: HIS6_STAAW
Sequence: MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGADELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSLNSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTTGGKKMTNIKVYDWVQQVEQLGAGELLVTSMGHDGMKQGFDIEHLANIKSLVNIPIIASGGGGNAQHFVELFDQTDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWP82_YEAST
Sequence: MLGEDEGNTVLEKGNNPSVKQGEVGAVFIVPKILIREHERVILKQILQILDQDELVQPPLDKFPYKKLELPKYIDELKTRDATNTSYKMIQLDAYGEKKVGSNGELFGGRHYLFNTFTFTAHMGVLLVLLQDVIKVLYQSNATHDEDEFIVQHDQILVMETSEEQTKFLAKNGVIPEESKGSFKYITARSAFVEFGASVIAGGQRIVDDYWESLAKKQNLSSHQRVFKLSTNLISKISLLRPSFQNNRISNANEISANTNNTCTISTSKFESQYPIVTEQPSAEIREAYIENFAKGEHISAIVPGQSISGTLELSAQFRVPRYHSKNSFQQALQMKAMDIPIGRHEELLAQYESQAPDGSASISLPNHIPSVNPSNKPIKRMLSSILDINVSSSKNKKSEENEMIKPMNKGQHKNNTSLNINGWKFESLPLKSAENSGKQQYYRGLPLYEKNTLLERLKQLTPNEIKELEHLHDAVFVNTGLQNVRKVRTKKWKKYWQYKAGIPIGLKRSQLDEFKNKYLKDVLAQTSVTTNFNEITNTDETITTKRVPNPNFLGNCNIKDFKPPYIYSHVNKVPQNVAGDKTAVKLDTEVKNTNANPVVATDPVAAKPDNLANFSNEVAMNN
What is the function of this protein?
Involved in transcriptional activation.  Component of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
SWI/SNF global transcription activator complex subunit SWP82.
What is the protein family that this protein belongs to?
Belongs to the RSC7/SWP82 family. SWP82 subfamily.
Protein: MIAB_COREF
Sequence: MNTHPSHPDHPADTLPARGNREGTTARTYEVRTFGCQMNVHDSERLSGLLEEAGYTAAGEGDTPDLIVFNTCAVRENADQRLYGTLGNLRAVKENHPGMQIAVGGCLAQKDKDTVVKKAPWVDVVFGTHNIASLPTLLNRAEHNQKAEVEIVDSLEQFPSVLPAKRESAYAGWVSVSVGCNNTCTFCIVPSLRGKEQDRRPGDILAEVQALVDQGVSEVTLLGQNVNAYGVNFVDPELERDRSAFSKLLRACGDIEGLERVRFTSPHPAEFTSDVIDAMAETPNICPQLHMPLQSGSDRVLKEMRRSYRSAKFLAILDEVRAKIPHASITTDIIVGFPGETEEDFQATLDVVEKARFTSAYTFQYSPRPGTPAADYENQVPKKVVQERYERLMALQERICEEENQKFIGQTVELLVQAGGGRKNDATKRMSGRARDGRLVHFTPVGTIDGEIRPGDVVTVEVTEAKPFFLIADAGVLTHRRTRAGDNSAVGQVPTTAPIGVGLGLPRIGAPVPAPATPDNACGC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHB_PROA2
Sequence: MRLAFWLYEGTALHGISRVTNSMKDVHTVYHAPQGDDYITATYTMLERTPQFPGLSISVVRGQDLARGESRLPATLQQVEEHYNPRMIVVAPSCSTALLQEDLEQLSRHSGVDPDKILVYDVNPFRVQEHEAAEGLFTELVKRSAQPQTLTEQPSVNLLGFTSLGFHLRSDLTSLRRILKTLGITINVVAPWGASMDDLSRLPSAWVNVVPYHEMGNGAARYLREKFGMPILSGAPMGVNPTLKWIEDLLAQINDIARERGLPLLDMPDLTEFSLDGLSAPSGVPWFARTADMESFSGKRAFVFGDATHTVGMVKFLKDELGMQIIGAGTYLSRHADWVRSELEGYLPEPLIVTDKFQEISKKIEDEMPELVCGTQMERHSCRKLDVPCMVISTPTHIEDHLIAYYPILGFEGADILADRVYTSCKLGLEKHLIDFFGDAGLEYEDDEEAVGLSTNGHAAAETETSIAGEAATVVSAEGDGMPWTDDAEKMLKKVPFFVRKKVRKNTENYAREIGETTISGDVFRKAKEALGG
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The NB-protein (BchN-BchB) is the catalytic component of the complex.
What are the official names of this protein?
Light-independent protochlorophyllide reductase subunit B, DPOR subunit B, LI-POR subunit B.
What is the protein family that this protein belongs to?
Belongs to the ChlB/BchB/BchZ family.
Protein: SYA_FUSNN
Sequence: MLTGNEIREKFIEFFMQKQHKHFESASLIPDDPTLLLTVAGMVPFKPYFLGQKEAPCPRVTTYQKCIRTNDLENVGRTARHHTFFEMLGNFSFGNYFKKEAIKWSWEFVTEVLKINKDKLWVTVFTTDDEAEKIWIEECNFPKERIVRMGESENWWSAGPTGSCGPCSEIHVDLGIQYGGDENSKIGDEGTDNRFIEIWNLVFTEWNRMEDGSLEPLPKKNIDTGAGLERIAAVVQGKTNNFETDLLFPILEEAGKITGSQYGKNPETNFSLKVITDHARAVTFLVNDGVIPSNEGRGYILRRILRRAVRHGRLLGYKDLFMYKMVDKVVEKFEIAYPDLRKNVENIRKIVKIEEEKFSNTLDQGIQLVNQEIDNLLTNGKNKLDGEISFKLYDTYGFPYELTEEIAEERGVIVLREEFEAKMEEQKEKARSAREVVMEKGQDSFIEEFYDKYGVTEFTGYEKTEDEGKLLSLREAKDRKYLLIFDKTPFYAESGGQVGDQGKIYSDNFAGKVLDVQKQKDIFIHTVKLEKGMPEENKTYKLEVDVVKRLDTAKNHTATHLLHKALREIVGTHVQQAGSLVDSEKLRFDFSHYEALTEEQLSKIEDIVNKKIREGIEVVVSHHSIEEAKKLGAMMLFGDKYGDVVRVVDVHGFSTELCGGTHIDNIGKIGLFKITSEGGIAAGVRRIEAKTGYGAYLVEKEEADILKNIEQKLKATNSNLVEKVEKNLETLKDTEKELEILKQKLALFETKAAISGMEEIGGVKVLIAAFKDKSTEDLRTMIDTIKDNNEKAIIVLASTQDKLAFAVGVTKTLTDKIKAGDLVKKLAEITGGKGGGRPDFAQAGGKDEGKLLDAFKEVREIIEAKLV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG26_KLULA
Sequence: MPKDSSEHQKSPSRFTRSMFVDPRAFVRRSVSPVDQLCHSVADLRFVSSNTETLESRLQALSKKFDNGSENHGQDTDTVEDVAKTQYMAKSFAGLIATASMYVGINELGDKEENDEDELELMNDAASVLDTSSQANQTLFEVSIEMNADAISQISTDSKSRKELIRERLIKKFLPNDDEKYIEEYPCWLLRDIMIQGHAYLTNKHLFFFAFIPNFESDFNVTGSLRLISGHVLSKSHRYWVVLKGHTLSFHNSSTDLYFPLLTIDLRDISSVQMTSSENNPTKFELSIKDQSLVLKADSFHSARHWVSSIKKQMFASQHSDTNTMTIKIPLQNIVDLEETSILDKSGTLRIKALENLSTYAVDEYFFVFFKGNANAMKQKVNSLLKDLEMNGSQILVNFNKVDSPLGINEKLPDLNYDDPSNENNLVDDADINSAETDTLSPGTMQSALTLQQTSSAFSPRHSAYPRKVKKKLKSMAGSLKLGSPSKFTKLEDDIIIEHYSPGLINDQTIDYDKDSKSIISRLTPKKFQNVPLMWAADPVHFNSDDGIVFPLDDKYTADADISNQSNVRFRQHFSFDETANLVASYHGYLNRNVPIYGKIYISDKNICFRSLLPGVSTKTVLPLEDVENCYKETRFRFGYFGLVIVIHGHEELFLEFGNKNARDDCEFVMIKVMDAVSSHRSTLKRKSTAEVVHRLSEAASLKLLEEKISEQGFDIPLIVEKNPYFTTVIKPSKSYKFGLLTIGSRGDVQPYIALAKGLQAEGHEVIILTHGEFKDWIVSHNIGFREISGNPAELISLMVQHGSMNMGLLRDASTNFSTWISSLLDTAWEGCQGIDILIESPSAMAGIHIAEALRIPYFRAFTMPWTRTRAYPHAFIVPDQKRGGNYNYFTHVLFENIFWKGISGKVNEWRETKLKLPKTNLVSMQQNRVPFLYNVSPIVFPPSVDFNEWIKVTGYWFLDEKRSYKPPAEFMEFLNKARELKKKVVYIGFGSIVVNDPEKMTDTIIEAVRDAGVYCVLNKGWSNRFGDPLAKKIDKELPSYIYNSGDVPHDWLFTKIDATVHHGGSGTTGASLRAGLPTIIKPFFGDQFFYASRVEDIGAGVALKKLNRSSLAKALKEVTTNTRIIQKARQIGESISKEHGVATAIGAIYSELGYARSLIKTKNPVDDKEMEAASTKLSNDAVVTAKGNEKEEYSSEGSGSNDGSWLLI
What is the function of this protein?
Probable sterol 3-beta-glucosyltransferase that is not involved in cytoplasm to vacuole transport (Cvt), pexophagy or nonselective autophagy (By similarity).
What are the official names of this protein?
Sterol 3-beta-glucosyltransferase, Autophagy-related protein 26.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.