PharMolix/UniProtQA huggingface dataset:
Protein: PURA_PSEP1
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEHAAAVVRYQGGHNAGHTLVINGEKTVLHLIPSGILREGVQCLIGNGVVVAPDALMREITKLEEKGVPVRERLRISPAAPLILSYHVALDQAREKARGEAKIGTTGRGIGPAYEDKVARRGLRVGDLFHRERFAAKLGELLDYHNFQLVNYYKEPAIDFQQTLDECMAYAEQLKPMMLDVTAELHNLRRAGKDIMFEGAQGSLLDIDHGTYPYVTSSNTTAGGISTGSGVGPMYLDYILGITKAYTTRVGSGPFPTELFDETGATLAKRGHEFGSTTGRARRCGWFDAVILRRAIDVNSISGICLTKLDVLDGLETINICVGYKNENGAVIDAPSDADSYIGLEPVYEEMPGWSESTLGVKTLEELPQAARDYIKRIEELVGAPIDIISTGPDRNETIVLRHPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF298_ARATH
Sequence: MSASKATMLILFALFLSDILLVSIPRAEAQLIVPCKTSEQCKSIRCSNGSAQCVNKQCQCPSLKQIYSVTDVSCKTVSDCVASHQCPTGLSACIEGKCICLP
What are the official names of this protein?
Putative defensin-like protein 298.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: NXF1_COTJA
Sequence: MAEEGKGGYSEHDDRVVGRGFSGRRKKGRGPFRGKMYSEMNRNSRNRGGTGPSSSRQRQDEDDGDVAMSDAHDAPRGRYLPYGPRPSRAPHLTVRRDLPPPDRSGGGSRDGGRRNWFKITIPYGKKYDKTWLLSSIQNLCSVPFTPVEFHYDHNRAQFYVEDATTASALKQVSRKITDRDNYKVVIIINSSAPPPSLQNELKPEEIEQLKVCMSKRYDGAQRALDLKGLRVDPDLVSQSIDVVLNQRSCMMVVLRIIEENIPELQSLNLSSNKLYRLDDLAELAIKAAGLKVLDLSRNELKSERELDKVKGLKLEELWLDGNPLCDGFRDQSSYISSVRERFPKLLRLDGHELPPPIAFDVEAPVTLPPCKGSYFGSDDLKVLVLRFLQQYYSIYDSSDRQGLLDAYHDGACCSLSIPFGPQNPPRNTLNEYFKDSRNVKKLKDPTMRFKLLKHTRLNVVAFLNELPRTQHDVSSFVVDVCAQTNTLLCFAVHGIFKEVDGKSRDSVRAFTRMFIAVPAGNTGLCIVNDKLFVRNATADELRKAFVMPAPTPSSSPVPSLAAEQQEMLAAFAMQSGMNLEWSQKCLQDNDWDYGRAGQVFTQLKLEGKIPEVAFLK
What is the function of this protein?
Involved in the nuclear export of mRNA from the nucleus to the cytoplasm.
What are the official names of this protein?
Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP.
What is the protein family that this protein belongs to?
Belongs to the NXF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Nucleus.
Protein: LPMG_ECOHS
Sequence: MEPDPTPLPRRRLKLFR
What is the function of this protein?
Makes mgtA transcription sensitive to intracellular proline levels.  Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene (By similarity).
What are the official names of this protein?
mgtA leader peptide, Regulatory leader peptide for mgtA.
What is the protein family that this protein belongs to?
Belongs to the MgtL family.
Protein: DER_STAA8
Sequence: MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RL9_STRPB
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAEAQAVKAVLDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLAITEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: X_HBVB1
Sequence: MAARLCCQLDPARDVLCLRPVGAESRGRPLPGPLGALPPASPSAVPSDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHRNLPKVLHKRTLGLSAMSTTDLEAYFKDCVFNEWEELGEEIRLKVFVLGGCRHKLVCSPAPCNFFTSA
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: RNFB_RHOCA
Sequence: MIAAAASMSALGLGLGYLLGAAARKFHVETPPIVEEIAKILPGTNCGACGFPGCNGLAEAMAEGNAPVTACTPGGRDVALALAEIVTVEAGADAGPIAEIEPMVAFVFEDHCTGCQKCFKRCPTDAIVGGAKQIHTVVMDACIGCDACIEVCPTEAIVSRVKPKTLKTWYWDKPQPGLVAASAETAA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane (By similarity).  Required for nitrogen fixation.  Involved in electron transfer to nitrogenase (PubMed:8264535).
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Nitrogen fixation protein RnfB, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cellular chromatophore membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GCH1_HELPG
Sequence: MENFFNQFFENIGEDKNREGLKETPKRVQELWKFLYKGYKEDPKVALKSAYFQGVCDEMIVAQNIEFYSTCEHHLLPFFGNISVGYIPKEKIVGISAIAKLIEIYSKRLQIQERLTTQIAETFDEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDPKTRAEFMQLLKS
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RL29_STRPQ
Sequence: MKLQEIKDFVKELRGLSQEELAKKENELKKELFDLRFQAAAGQLEKTARLDEVKKQIARVKTVQSEMK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: DCD_ACIBS
Sequence: MAIKSDRWIREMSEKHGMIEPYAENQVRFDKNGEKLISYGVSSYGYDVRCAREFKVFTNVHSAIVDPKNFDEKSFIDIESDVCIIPPNSFALARTIEYFRIPRNVLTVCLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPARIYAGEGVAQMLFFESDEVCETSYKDRGGKYQGQTGVTLPKT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: Y1633_STRA5
Sequence: MKDFIEWKDFTFQYDVQSEPTLKGINLSIPKGEKVLILGPSGSGKSTLGHCLNGIIPNTHKGQYSGIFTINHKNAFDLSIYDKSHLVSTVLQDPDGQFIGLTVAEDIAFALENDVVAQEEMASIVEMWAKRLEIAPLLSKRPQDLSGGQKQRVSLAGVLVDDSPILLFDEPLANLDPQSGQDIMALVDRIHQEQDATTIIIEHRLEDVFYERVDRVVLFSDGQIIYNGEPDQLLKTNFLSEYGIREPLYISALKNLGYDFEKQNTMTSIDDFDFSELLIPKMRALDLDKHTDKLLSVQHLSVSYDLENNTLDDVSFDLYKGQRLAIVGKNGAGKSTLAKALCQFIPNNATLIYNNEDVSQDSIKERAERIGYVLQNPNQMISQAMVFDEVALGLRLRGFSDNDIESRVYDILKVCGLYQFRNWPISALSFGQKKRVTIASILILNPEVIILDEPTAGQDMKHYTEMMSFLDKLSCDGHTIVMITHDMQLMLEYTDRAIVIDNGLIVADDHPINILSNTELLKKTHLKKTSLFALADRLGISPQKLTQWYIDNQGGKNG
What is the function of this protein?
Probably part of an ABC transporter complex.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative ABC transporter ATP-binding protein SAG1633.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ENGB_MARMM
Sequence: MGAVALDHLPEPDRLEVAFAGRSNVGKSSLINALTNQKGLARASGEPGRTRELNFFNVEGGDLRIVDLPGYGYAKAPKPVVEKWTRLTKAFLRGRVNLKRVYLLIDSRHGLKDVDLKIMDVFDEAAVSYQVVLTKTDKIKPPAVKRLIGETGEKIARRPAAFPRVIATSSAKQDGVDQLRAEIVALLPDMG
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: Y4AQ_SINFN
Sequence: MSRIILSLDAENADLKARVAFLEQQLFGPKSEKMTAIDPTQATLDLGDLTDIPAAANDDVAPVAEGPKQERRSPSRNIGRLPRHLPRYEELIEPESKICPCCSFELHCVGTDVSEALDIVPAVVRVKQTIRPSYACRAGESVIVQAPASARVMGESNVAPMRLAFCLAHARRKFVDVVKLTGSSEAGR
What are the official names of this protein?
Uncharacterized protein y4aQ.
What is the protein family that this protein belongs to?
Belongs to the transposase 25 family.
Protein: J_BPG4
Sequence: MKKSIRRSGGKSKGARLWYVGGTQY
What is the function of this protein?
Mediates ssDNA packaging into virion, it locates to the internal surface of the capsid, thereby displacing the internal scaffolding protein B during virion formation.  Protein J binds to and is packaged with the viral ssDNA.  Additionally, protein J plays a role in viral attachment efficiency to the host cell.
What are the official names of this protein?
DNA-binding protein J, J protein, Small core protein.
What is the protein family that this protein belongs to?
Belongs to the microviridae J protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=situated at the interface between the internal surface of the capsid and the nucleic acid.
Protein: FADB_AERS4
Sequence: MIYQGETLSVSYLENGIAELRFDAPGSVNKLDRATLLSLSEAIAALQQQADLKGLILTSGKDAFIVGADITEFLELFDLPQEDLLGWLKKANDIFSAIEDLPVPTLSAIKGHALGGGCETILSTDFRLADTSAKIGLPETKLGIMPGFGGTVRLPRVIGADNALEWITTGKDYRADDALKVGAIDAVVAPDALHSAAVQMMKDAIAGKLNWQSRRAAKKAPLRLSKLEAMMSFSTAAGMVAAVAGKHYPAPMTAVKTVEAAAGMSRDEALVVEAQGFIKLAKTDVAKALVGIFLNDQHIKALAKKAAKQAAKATRHAAVLGAGIMGGGIAYQSASKGIPAVMKDINEKALALGMGEATKLLNGQLEKGRIDGIKMGQVLSAITPTLSYDNVKHVDLVVEAVVENPKVKAAVLGEVEGIIGDDAVLASNTSTIPISLLAKGLKRPQNFCGMHFFNPVHRMPLVEIIRGEQTSDETINRVVAYAAAMGKSPVVVNDCPGFFVNRVLFPYFFGFNKLVADGADFAAVDKVMEKEFGWPMGPAYLLDVVGIDTGHHAGDVMAQGFPARMSKEGRTAIDVMYDASRFGQKNGKGFYAYEQDKKGKPKKVADVAAYELLAPIAKPKQDFDKEAIIAGMMIPMINEVVLCLEEGIVATPAEADIALVYGLGFPPFRGGVFRYLDTIGLDRYVAMADQYADLGPLYRVSDRLREMAAQGKTFY
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: RS13_MESFL
Sequence: MARISGVEIPNEKRVVISLTYIYGIGLSTSQKVLSKLNISEDVRTRDLTEEQIKAISTEISNFKVEGELRREVSLNIKRLMEIGCYRGLRHRKGLPVRGQSSKTNARTVKGPRKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: S38A9_MOUSE
Sequence: MASVDGDSRHLLSEVEHEVSPGPMNIQFDSSDLRSKRPFYIEPTNIVNVNDVIQRVSDHAAAMNKRIHYYSRLTTPADKALIAPDHVVPAPEECYVYSPLGSAYKLKSYTEGYGKNTSLVTIFMIWNTMMGTSILSIPWGIKQAGFTTGMCVIVLMGLLTLYCCYRVVKSRSTISTSDTSTWEYPDVCKHYFGSFGQWSSLLFSLVSLIGAMIVYWVLMSNFLFNTGKFIFNFIHHINDTDTVLSTNNSNPVICPNAGSGGRPDNSSMIFYNNNTEVQLFEKWWDKSRTVPFYLIGLLLPLLNFKSPSFFSKFNILGTVSVLYLIFVVTLKAVRLGFHLEFHWFVPTEFFVPEIRAQFPQLMGVLTLAFFIHNCIITLLKNNKNQENNVRDLCIAYMLVTLTYLYIGILVFASFPSPPLPKDCIEQNFLDNFPSSDILSFIARIFLLFQMMTVYPLLGYLARVQLLGHIFGDIYPSIFHVLILNLVIVGAGVTMACFYPNIGGIIRYSGAACGLAFVFIYPSLIYIISLHQEERLTWPKLVFHVIIIILGLANLIAQFFM
What is the function of this protein?
Lysosomal amino acid transporter involved in the activation of mTORC1 in response to amino acid levels.  Probably acts as an amino acid sensor of the Rag GTPases and Ragulator complexes, 2 complexes involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.  Following activation by amino acids, the Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.  SLC38A9 mediates transport of amino acids with low capacity and specificity with a slight preference for polar amino acids.  Acts as an arginine sensor.  Following activation by arginine binding, mediates transport of L-glutamine, leucine and tyrosine with high efficiency, and is required for the efficient utilization of these amino acids after lysosomal protein degradation.  However, the transport mechanism is not well defined and the role of sodium is not clear.  Can disassemble the lysosomal folliculin complex (LFC), and thereby triggers GAP activity of FLCN:FNIP2 toward RRAGC.  Acts as an cholesterol sensor that conveys increases in lysosomal cholesterol, leading to lysosomal recruitment and activation of mTORC1 via the Rag GTPases.  Guanine exchange factor (GEF) that, upon arginine binding, stimulates GDP release from RRAGA and therefore activates the Rag GTPase heterodimer and the mTORC1 pathway in response to nutrient sufficiency.
What are the official names of this protein?
Neutral amino acid transporter 9, Solute carrier family 38 member 9.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SLC38A9 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein.
Protein: HPRK_LISMH
Sequence: MTKSVTVKDLKERLNLELICSETGLERPISTSDLSRPGLELTGFFSYYPEDRVQLFGMTEISFSEGMEPEERLKRYKQMCTKRTPAFVISRNLEVPKELVAAAKEADIPVLRSRLKTTRLSVYITNYLESRLAPVISMHGVLVDIYGLGVLITGSSGVGKSETALELVKRGHRLVADDNVEIRQEDEMTLIGSSPAIIEHLLEIRGLGIINVMTLFGAGAVRSSKKITIVVHLENWDPDKHYDRVGLDQEKTKIFDMDIPKITVPVRPGRNLSVIIEVAAMNFRLKNMGYNAAEQFTQDLNNLIGHNSSMND
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: Y073_METJA
Sequence: MKVDREKYGSEKIAKLKILEELKKENPNKKIIAIGNGNNDELLLKNADLGICVIGDEGAWSKTILSSDIVVKDINDALDLLLNENRLKATSRD
What are the official names of this protein?
Uncharacterized protein MJ0073.
Protein: RL1_LEPCP
Sequence: MAKLTKRQKAQVGKIETTKLYAVDDAIALIKEFAVAKFDESIDVAVQLGVDAKKSDQVVRGAVVMPNGTGKTKRVAVFTQGAKADEARAAGADIVGMDDLAAEVKAGNINFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTADVATAVRNAKAGQVQFRVDKGGIIHGTIGRRSFDTDKLKGNLQALLDALNKAKPASSKGVYLRKVAVSSTMGVGVRVEVASITAGLAAQS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: UL84_HCMVM
Sequence: MPRVDPNLRNRARRPRARRGGGGGVGSNSSRHSGKCRRQRRALSTPPLTFLATTTTTTMMGVASTDDDSLLLKTPDELDKHSGSPQTILTLTDKHDIRQPRVHRGTYHLIQLHLDLRPEELRDPFQILLSTPLQLGEANGESQTAPATSQEEETAASHEPEKKKEKEEKKEEEDEDDRNDDRERGILCVVSNEDSDVRPAFSLFPARPGCHILRSVIDQQLTRMAIVRLSLNLFALRIITPLLKRLPLRRKAAHHTALHDCLALHLPELTFEPTLDINNVTENAASVADTAESTDADLTPTLTVRVRHALCWHRVEGGISGPRGLTSRISARLSETTAKTLGPSVFGRLELDPNESPPDLTLSSLTLYQDGILRFNVTCDRTEAPADPVAFRLRLRRETVRRPFFSDAPLPYFVPPRSGAADEGLEVRVPYELTLKNSHTLRIYRRFYGPYLGVFVPHNRQGLKMPVTVWLPRSWLELTVLVSDENGATFPRDALLGRLYFISSKHTLNRGCLSAMTHQVKSTLHSRSTSHSPSQQQLSVLGASIALEDLLPMRLASPETEPQDCKLTENTTEKTSPVTLAMVCGDL
What is the function of this protein?
Plays an essential role in viral DNA replication.  May participate in the DNA replication initiation by interacting with the origin of lytic replication, oriLyt and subsequently recruiting other viral/cellular factors.  Additionally, interacts with and shuttles IRS1 viral mRNA from the host nucleus to the cytoplasm (By similarity).
What are the official names of this protein?
Protein UL84.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL84 protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Shuttles between host nucleus and cytoplasm. In the nucleus, colocalizes with UL44 and IE2 in the viral DNA replication compartments (By similarity).
Protein: Y4JB_SINFN
Sequence: MDERNDSARSEAMFEARHEGRYRRVEVITGPVRRRNWTDEEKALMLAESAEPDANISAIARRFGVNRGLLNTWRRAAGQIGPVLGEPALEQPAFVPIRIADDQNEHQADEAGIAEGAAGRIEIELGGGRMIVTGNVSPDLAHAVVMALRGRR
What are the official names of this protein?
Uncharacterized protein y4jB.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: H1_CHITH
Sequence: MSDPAIEVAPVPVASPAKAKKEKKPKSDKPKKPKAPRTHPPVSDMIVNAIKTLKERGGSSVQAIKKFLVAQYKVDTDKLSPFIKKYLKSAVEKGQLLQTKGKGASGSFKLPAAAKKEKVVKKVTKKVTEKKPKKAVSKPKTGEKKVKKTIAKKPKVASATKIKKPVAKTTKKPAAAKPTKKVAAKPKAAPKPKAAPKPKVAKPKKAAAPKAKKPAAEKKPKAAKKPSAKKA
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL18_CLOBM
Sequence: MFKKNDRSQSRERRHMRVRKKIFGTAERPRLSVYRSEKHIYAQLIDDVEGKTLVAASSSEKGFDGVGSNKEGAKLVGKMIAEKALEKGLKKVVFDRGGFIYHGRIKELAEGAREAGLDF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PPA5_HUMAN
Sequence: MDMWTALLILQALLLPSLADGATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP
What is the function of this protein?
Involved in osteopontin/bone sialoprotein dephosphorylation.  Its expression seems to increase in certain pathological states such as Gaucher and Hodgkin diseases, the hairy cell, the B-cell, and the T-cell leukemias.
What are the official names of this protein?
Tartrate-resistant acid phosphatase type 5, TR-AP, Tartrate-resistant acid ATPase, TrATPase, Type 5 acid phosphatase.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. Purple acid phosphatase family.
What are the subcellular locations of this protein?
Lysosome.
Protein: YACG_BRUSU
Sequence: MTPLRPTRPCPECGKPSTREAYPFCSPRCKNIDLNRWLSGSYVIAGKPLGEEDENDS
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: EVI5_HUMAN
Sequence: MVTNKMTAAFRNPSGKQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSTSLHTTSSSTTLSTPALSPSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHELRCLKGQRGFSGQPPFDGIHIVNHLIGDDESFHSSDEDFIDNSLQETGVGFPLHGKSGSMSLDPAVADGSESETEDSVLETRESNQVVQKERPPRRRESYSTTV
What is the function of this protein?
Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase.  May play a role in cytokinesis.
What are the official names of this protein?
Ecotropic viral integration site 5 protein homolog, EVI-5, Neuroblastoma stage 4S gene protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis.
Protein: MU143_SCHPO
Sequence: MIRYSLNGIRLFGSLNLFNATRILPISLGRASYAHARLFTSKVEKSGTAEESALPSVDEEEDKLNSLLGNIKVRTAQEDGVSVEEVLMHHPELLRNAPHALQQSVKEILASKEVGDAFKKN
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 143 protein.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS6_MYCGA
Sequence: MAKYEIMLMVSGQLNQNQAQAVNDELKAVFGKTEITEEYLGQKTLEYPIKKEVTAHYFNLFLTSDGKSVHEYKRLASIRTDVLRILILNTEKEFGYRASQNAKKVALAKQKQARYNDIMKQVQENGYFQIKGSKRNSRVEKAGAKEVWMLREKFGEDLPEQKIPVLRKVNLTRKPTPNKSSENKQKVEKQA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.