PharMolix/UniProtQA huggingface dataset:
Protein: LMLN_CAEBR
Sequence: MKPRLIFQYFAYSFLVFLPFINTLPCSYQNPRIEDVLLEVPIEHHHPHRHRRDSENPTETPPDLQKFAPLRIQLHYDKSIQNLTAEVQHFVNTTLLPEAVGYWENALRVRPMKTPIRLRRKCISSFYYYKQGMRNVACDKGCRERTTCGEADIPNDHLLDCLACNNTDDCQTTGEMGEGVKESDFILYVTAHNSKRCEGPETLSYAAHCQQEADFDRPIAGNVNLCPSALSVHNHDYEILTSTVKHEILHALGFSVGLYAFFRDKDGKPRTKRNRYGRPTSLNKQRGYYDWDKNTITTVLREEWWTGEGKVIHPIQMMVTPKVREEARRHFGCDKLEGAELENQGGEGTVLTHWEKRAYENEAMTGTHTQNPVYSRLTLAFLEDTGWYQPNYEVAEDLHWGKQLGCDFAMKSCGEWIHQKRILGEDAYPYCSDIKHDGTKSMAITRCTSQRDSLALCNLIPFQKELPPQYRNFMSLPGVNPDGAKYYGGSVEMADYCPFLQEFEWKMPEKEHKDSRCELEGNGKEGEDILEVYGENSKCFEFPKPWTERKCGRIRVLSHYMAGCYEYQCTNGTLYVGSYNATDMYPCYAENQKVHIKKVVDGWLREGSLICPKCSDYCSSCGPPIVIPDYIGDPELDEPCFAFSKFSVFGLFSCYLAILYIRF
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Leishmanolysin-like peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M8 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Found in ring-like structures resembling invadopodia. In migrating cells it relocalizes from internal structures to the leading edge of cells (By similarity).
Protein: AVH23_PHYSO
Sequence: MRLTYFLTVIVVATLHAGGTALATAEAPNHAAIVNVASADNVHSLDTTAEIGGRMLRKVKEDTVSKKDHEERGPGAILERQTAFVKKLFSRQNAIVNRAQGAFQRQNAFVNRDQGAFQRQNAFVKRAIQRQNHFKLSDNA
What is the function of this protein?
Effector that suppresses plant defense responses during the early stages of pathogen infection.  Suppresses cell death induced by effectors and PAMPs in plant hosts (PubMed:21653195).  Acts as a modulator of histone acetyltransferase (HAT) in plants.  Avh23 binds to the ADA2 subunit of the HAT complex SAGA and disrupts its assembly by interfering with the association of ADA2 with the catalytic subunit GCN5.  As such, Avh23 suppresses H3K9 acetylation mediated by the ADA2/GCN5 module and increases plant susceptibility (PubMed:28318979).
What are the official names of this protein?
RxLR effector protein Avh23, Avirulence homolog protein 23.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm. Note=Location into the host nucleus is required for virulence.
Protein: RL15_NOCSJ
Sequence: MTLKLHNLRPAPGAKTAKTRVGRGEGSKGKTAGRGTKGTKARYQVPAAFEGGQMPIHMRLPKLKGFKNPFKVEFQVVNLDRINQLFPEGGAVGVEDLVAKGAVRDGHPVKVLGQGEISVAVQVSANAFSATASEKIEAAGGTTTLV
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: MURB_CALS4
Sequence: MAEILVDKLKEILKEGKLYLNEPMKRHTSFKIGGPADVLAVPGSRDELINLIAYLRQEKIPFFILGNGTNLLVSEKGIRGVVVKLSSLRNVIVEGTKIIAEAGASLSYIANVALVHELTGFEFASGIPGTLGGAIVMNAGAYGSEMKDVVEKVEVLDENNNILILSNQEMKFSYRYSILQEKEWIVLRAWISLERGNYEEIKKKMEELNQRRKEKQPLDYPSAGSTFKRPPGYYAGKLIEDAGLKGYSIGGAKVSEKHSGFIINTGNATFYDVLNLIEYIQKVVKEKFGVELMPEIKIVGEK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_CHLTE
Sequence: MRAVLLVSGGMDSLVATALAHREGLELAAMHVNYGQRTWQKELECFRQICVHYGIVDRLEVDAMFLSAIGGSSLTDATIPVGPADLAGTDIPTSYVPFRNANFLSMAVSWSEVIGANRIYIGAVEEDSSGYPDCRKVFYDAFNQVIEHGTRPETRIEIVTPLIAMSKAEIVRRGMELDAPFHFSWSCYKSEGKACGVCDSCARRLRAFASVGMDDPVEYEVRPNYLQ
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: BIOF_HAEIG
Sequence: MDAFKQQLEQLSAQNQYRSIPDLVHQGRYIMRENRKMLNMSSNDYLGLASNENLRQSFLQQYGGNFPSFTSSSSRLLTGNFPIYTDLEELVAQRFQRESALLFNSGYHANIGILPALTTKSLILADKLVHASMIDGIRLSQCEFFRYRHNDYEHLKNLLEKNVGKFDRTFIVTESVFSMDGDVADLKQLVQLKKQFPNTYLYVDEAHAIGVYGKNGLGIAERANVIADIDLLVGTFGKALASMGAYVVCDQILKECLINQMRPLIFSTALPPFNVAWTYFIFERLPQFSKERSHLERLSAFLRQEVEHRTQIMPSQTCIVPYILGENEATLAKAKDLQEQGYYCLPIRPPTVPKGTSRIRLSLTADMTMDEVKQFVACL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: SYGB_ALIFM
Sequence: MAKNFLIELGTEELPPTALRSLAEAFASNFEAELKAADLAHQGVKWYATPRRLALKVAELAESQADKVVEKRGPAVSAAFDADGNPTKAAQGWARGNGITVEQAERLKTDKGEWLLHKEEVKGKPVQELVVDFAAKALAGLPIPKAMRWGNSDIQFIRPVKTLTILLGDELIEGSILGVSSARTLRGHRFMGESEFTIDSADQYPAILEERGKVMADYDARKAIILADSEKAAAAVGGKADLEDDLVEEVTSLVEWPVVLTAKFEEEFLKVPSEALVYTMKGDQKYFPVYDENKKLLPNFIFVSNIESKEPRHVIEGNEKVVRPRLADAEFFFNTDRKRPLIDRLPELEQAIFQKQLGTIKDKTDRITELAGYIAEQIGADVEKSQRAGLLAKCDLMTSMVFEFTDTQGVMGMHYATHDGEDEQVALALYEQYMPRFAGDDLPSTDISASVAMADKLDTLVGIFGIGQAPKGSDPFALRRAALGVLRIIVEKEYNLDLVDLVAKAQSLFGDKLSNANVATDVIDFMLGRFRAWYQDEGFSVDIIQAVLARRPTKPADFDKRVKAVSHFRELDAAESLAAANKRVGNILAKFDGELAQEIDLALLQEDAEKALAEKVEILAEALEPVFAAGNYQEALSRLAELREPVDAFFDNVMVMADDEALKTNRLTLLNKLRNLFLDIADISLLQK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_MYCGA
Sequence: MANENIQIKSSLDDLKNFVQNPKSQNQKIKAVNQLMYNEFVKIETAINNINNYIENLTHRLELTNENFKTKVQEVESKAQQKINDRIEELDKRKKEEIENAKKYAIEKSIDSAINIVDQLEIALEFASLDPAVKNYVSGFKMVLNSFVNWLASVNIHRMDIKPGDKFDEKYMSASDKASDPDYPADHVCKVMKSGYKLYDRVVRHAMVAVSDGVGYVEPASSEQEQPQTPAKSTQTPPAQETASAPAKTKPTAPPTNNLNANKPPVVSNPPHQKPVQPPQSNTPGPKQPITHQVIKKS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHS7_IPOBA
Sequence: MVTVEEVRKAKRAEGPATILAIGTATPANCVNQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMITKRYMHLTEEILKENPSFCEYMAPSLDARQDIAVVEVPKLGKEAAQSAIKEWGQPKSKITHVFFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLIVCSEITVVTFRGPSETHLDSLVGQALFGDGAAAVIVGADPTPAEKPLFQLVSAAQTLAPDSCGAIDGHLREVGLTFHLLKDVPSVVSNNIEKCLFEAFNPLGISDWNSVFWIAHPGGPAILDQVEDKLGLKPEKLRATRHVLSEYGNMSSACVLFILDEMRKASSNAGLGTTGEGLEWGVLFGFGPGLTIETVVLHSVPIKPGPH
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase DIII, Naringenin-chalcone synthase DIII.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: PANC_CYTH3
Sequence: MISITSIQQLRLHLAEEKRKNHSVGFVPTMGALHRGHISLIKQAKAENTVCVASIFVNPLQFNNPEDFNKYPIQRESDMKLMSEAGCDILFMPDVAEFYPTRPNMKIDIGLLDQILEGAHRPGHFSGVAIVVSKLFHIIEPGKAYFGQKDIQQVAVIRQLVSELNFPIEIIACPIIREESGLAMSSRNMRLSAQGKAVAANIYKALSVIEKQIKQDKVTVSDAQHAGKNYLNQFKEIEVEYLEIVAADTLEAITEYADQTKIAVCIAAYVEGVRLIDNLVIIL
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_STAAB
Sequence: MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIEQALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALDWDKASIELEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDDYIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITHSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSSITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSSTDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFLNVELSNFYLDYGKDILYIEQRDSHIRRSMQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVKSLV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLC_ECOL6
Sequence: MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNKPLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSRYYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSAGTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTEVSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGDAEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
What is the function of this protein?
HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda.  HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins (By similarity).
What are the official names of this protein?
Modulator of FtsH protease HflC.
What is the protein family that this protein belongs to?
Belongs to the band 7/mec-2 family. HflC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: WRK51_ARATH
Sequence: MNISQNPSPNFTYFSDENFINPFMDNNDFSNLMFFDIDEGGNNGLIEEEISSPTSIVSSETFTGESGGSGSATTLSKKESTNRGSKESDQTKETGHRVAFRTRSKIDVMDDGFKWRKYGKKSVKNNINKRNYYKCSSEGCSVKKRVERDGDDAAYVITTYEGVHNHESLSNVYYNEMVLSYDHDNWNQHSLLRS
What is the function of this protein?
Transcription factor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).  Involved in defense responses.  May act as positive regulator of salicylic acid (SA)-mediated signaling and negative regulator of jasmonic acid (JA)-mediated signaling (PubMed:21030507).
What are the official names of this protein?
Probable WRKY transcription factor 51, WRKY DNA-binding protein 51.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-c family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASSY_EDWI9
Sequence: MATQSISKIVLAYSGGLDTSAIIPWLKENYGDCEVIAFVADIGQEREDLVGIEQKALRSGAASCYVVDLRETFIKDYVYPVLKSGALYEGSYLLGTSMARPLIAKAQVELALELGADALCHGATGKGNDQVRFETTYTALAPQLQVVAPWREWDLRSREALLDYLKGRDIPTTATLEKIYSRDANAWHISTEGGVLESPWSPANQDCWVWTCAPEEAPDQPELVTVGVEKGEVVSVNGVAMTPFGCLQALNALGTRHGVGRIDIVENRLVGIKSRGCYETPGGTIMMAALRGVEQLVLDRDSFQWREKLGQEMSYVVYDGRWFAPLRQSLQAAADALADAVSGEVVIKLYKGQAIAIQKKSVNSLYNEAFATFGEDDVYDHSHAGGFIRLFSLSSRIRALNSAKQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPU_HV1J3
Sequence: MQSLIAAIVALVVVAIIAIVVWSIVFIEYRKILRQRKIDRLIDRIRERAEDSGNESEGDQEELSALVEMGHDAPWDIDDL
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: ATPB_VEREI
Sequence: MAQAEAVQGKIVQCIGAVVDVEFPRDKMPKIYDALKFEGSALTLEVQQQLGDGVVRTIALGSSDGLRRGLIVTNTQAPITVPVGKATLGRIMDVLGAPIDERGPVDQTLTASIHRKAPAYDELSPSQDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMADSGVVNLEKLENSKVAMVYGQMNEPPGNRLRVALTGLTIAESFRDEGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKVGSITSIQAVYVPADDLTDPSPATTFAHLDSTVVLSRDIASLGIYPAVDPLDSTSRQLDPNVVGQEHYNVARAVQGTLQRYKELRDIIAILGMDELAPEDKLAVARARKIQRFLSQPFHVAEVFTGSPGKYVPLSETIRGFKMIVNGEADHLPEQAFYMVGTIDEAFEKAKKVA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UVRC_CHRSD
Sequence: MSFDAKHFLKTVSESPGVYRMLDAEGNVLYVGKAKRLKARLASYFRGALNAKTQALVSRIEDIQVTITRTETEALLLEQTLIKEQRPPYNILLRDDKSYPFIFVSDRHPYPALEFKRARQKRGDGRYLGPFPSTTAVRESLSLMQKIFRIRNCEDSVFAHRTRPCLQYQIQRCSAPCVDYIGREEYQRDIDHAIMCLEGRSEQVTAQLTRDMETASQALDFEEAARLRDQIQQLRRLQERQIVDTGDGDADIFALAERPGGLCISALAVRGGRMLGARHHMPQNGLDLTAEALLGEFISHYYLGHEREIPAEVITALPLADSDVIQAALSERAGKRIRLAHQVRGHRAQWLRLAETNAEQHLTTQLANRSQLAKRFASLRDAMQLQETPTRLECFDISHSHGEATVASCVVFDQDGPVKSDYRRFNIEGVAAGDDYAAMRQALTRRYKRLTQDDSKLPGILIVDGGKGQLNMAREVLEDVGITGTHLLGVAKGTTRKPGLETLFLETVDNSLALDSASPGLHLIQHIRDEAHRFAITGHRQQRDKQRRTSTLQDIPGIGPKRRRELLRFFGGLQGVRQASRDELARVPGISAQMATTIHQALHG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_WIGBR
Sequence: MIDKSAYVHPSSIVRKNAIIHANSYVGPFCFIDSQVEIGARTVLKSHVIINGLTYVGEDNFIYQFSSIGEENQDLKYSGENTKVYIGDRNKIRENSTIHRGTVQSNKITKIGNDNLFMVNVHIAHDCVIENNCVMANNVTLGGHVKIGNHVVIGGMTAVHQNCIIGSHVMIGGCSGISQDVPPFILAQGNHAIPFGINFEGLKRRGFDKKTISVIKNAYKIIYKRGNNLNNIKKELIKLSESNKIINLFLDFFSNSSRGFIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L25_OPHHA
Sequence: TKCYKTGDRIISEACPPGQDLCYMKTWCDVFCGTRGRVIELGCTATCPTVKPHEQITCCSTDNCDPHHKMLQ
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin OH-5, Alpha-neurotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CH3L1_RAT
Sequence: MTLQLPGFAVLMLLQSCSAYKLVCYYTNWSQYREGNGSCFPDALDHSLCTHIIYSFANISNNKLSTSEWNDVTLYGMLNTLKTRNPRLKTLLSVGGWSFGSERFSRIVSNAKSRKTFVQSVAPFLRTYGFDGLDLAWLYPGPKDKQHFTTLIKELKAEFTKEVQPGTEKLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRHTTGHHSPLFRGQQDTGPDRFSNVDYGVGYMLRLGAPTNKLVMGIPTFGKSFTLASSENQVGAPITGSGLPGRYTKEKGTLAYYEICDFLRGAEVHRILGQQVPFATKGNQWVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNVHFPLTNAIKEALAVA
What is the function of this protein?
Carbohydrate-binding lectin with a preference for chitin.  Has no chitinase activity.  May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment.  Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation.  Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs.  Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells.  Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance.  Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung (By similarity).
What are the official names of this protein?
Chitinase-3-like protein 1, Cartilage glycoprotein 39, CGP-39, GP-39.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.
Protein: RR4_EQUAR
Sequence: MSRYRGPRLRIIRRLRNLPGLTNKLVESKKNQASGNDQSNQKKVSQYCIRLEAKQRLRFNYGLTERQLLNYVRIARCAKGSTGQILLQLLEMRLDNILFRLGVVPTIPSARQLINHRHILVNNRIVDIPSFHCKPKDIITIGAPKTYQSIITKRIEAFAKDQIPDHLTLSLSEQKKPKGFVNYLINRESIGLKINELLVVEYYSRKA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: THII_SHIF8
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLTIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVETVNGFGPNDVILDIRSVDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNKTWLLWCERGVMSRLQALYLREQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_HAEIN
Sequence: MVKLNFSRELRLLTPIQFKNVFEQPFRASTPEITILARKNNLEHPRLGLTVAKKHLKRAHERNRIKRLVRESFRLSQHRLPAYDFVFVAKNGIGKLDNNTFAQILEKLWQRHIRLAQKS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: NQRC_VIBAN
Sequence: MASNNDSIKKTLFVVIALSLVCSIIVSTAAVGLRDKQKVNAVLDKQSKIVEVAGINESGSVPELFAKYIEPRLIDFKTGNFVDGDATAYDQRKASKDPAQSIKLTAEQDKAKIIRRANTGVVYLVKSGDEISKVIVPVHGNGLWSMMYAFVAVETDGNTVSGITYYEQGETPGLGGEVENPSWRAQFVGKKLFDDNHQPAIKVVKGGAPAGSEHGVDGLSGATLTSNGVQHTFDFWLGDMGFGPFLAKVRDGGLN
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit C, Na(+)-NQR subunit C, Na(+)-translocating NQR subunit C, NQR complex subunit C, NQR-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the NqrC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RR14_CRUWA
Sequence: MAKKSLIYREKKRQKLEKKYHLIRRSSKKEISNIPSLSEKWKIHGKLQSPPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.