PharMolix/UniProtQA huggingface dataset:
Protein: HEM1_NEIMF
Sequence: MQLTAVGLNHQTAPLSIREKLAFAAACLPEAVRNLARSNAATEAVILSTCNRTELYCVGDSEEIIRWLADYHSLPIEEISPYLYTLGMQETVRHAFRVACGLDSMVLGEPQILGQIKDAVRVAQEQESMGKKLNALFQKTFSVAKEVRTDTAVGENSVSMASASVKLAEQIFPDIGDLNVLFIGAGEMIELVATYFAAKSPRLMTVANRTLARAQELCDKLGVNAEPCLLSDLPAILHEYDVVVSSTASQLPIVGKGMVERALKQRQSMPLFMLDLAVPRDIEAEVGDLNDAYLYTVDDMVNIVQSGKEARQKAAAAAETLVSEKVAEFVRQQQGRQSVPLIRALRDEGEKARKQVLENAMKQLAKGATAEEVLERLSIQLTNKLLHSPTQTLNKAGEEDKDLVHAVAQIYHLDK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: SSUB3_ALKCK
Sequence: MAIAKQTTKRGVEIRIAQLQKTFGDQNVIKDITLTIEAGQFVAIVGKSGSGKSTLLRLVAGLEQPSSGDLLFNGATLKKSQASITMMYQDSRLLPWKKVIDNVGLGLKGNWQQKGESVLHAVGLSAFSNEWPSTLSGGQQQRVALARALIREPDLLMLDEPLSALDALTRSEMQDLIETIWQENQFTALLVTHDVREAVKLADRIILIEEGVIALDVENPLSRPRDVTNKQLIELEKQVTSRILEKE
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: S6A11_MOUSE
Sequence: MTAEQALPLGNGKAAEEARGSETLGGGGGGAAGTREARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCGHEWNTEKCVEFQKLNFSNYSHVSLQNATSPVMEFWERRVLAISDGIEHIGNLRWELALCLLAAWTICYFCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNNYNNNCYRDCIMLCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAESGPGLAFIAYPKAVTMMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRRELLILALSIISYFLGLVMLTEGGMYIFQLFDSYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPLSLIKWCWKVVTPGICAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWLMALSSMLCIPLWIFIKLWKTEGTLPEKLQKLTVPSADLKMRGKLGASPRTVTVNDCEAKVKGDGTISAITEKETHF
What is the function of this protein?
Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed:8420981, PubMed:30270321).  Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (PubMed:8420981, PubMed:30270321).
What are the official names of this protein?
Sodium- and chloride-dependent GABA transporter 3, GAT-3, Sodium- and chloride-dependent GABA transporter 4, GAT-4, Solute carrier family 6 member 11.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A11 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YO055_YEAST
Sequence: MCTDVAFFSLDCLATWLGGVCSTSDLRLPNFGSLNVTVGILFNPGSGVLLTTAPEVPLAFMIDLVCEPVGLVDFLTTGVSRLETEENGPVEFVSGIADEPILACSAPERVFEATPFLLFFRLDLFVIASLHYNYGQYSSFWSLL
What are the official names of this protein?
Putative uncharacterized protein YOR055W.
Protein: RL15_HYPNO
Sequence: MGAYKYMQELWRKKQSNVMRFLLRVRCWQYRQLSSLHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQIKFARSLQSVAEERAGRHCGGLRVLNSYWVGEDSTYKFFEVILIDTFHKAIRRNPDTQWITKAVHKHREMRGLTSAGKKSRGLGKGHKFHLTIGGSRRAAWKRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DENR_LODEL
Sequence: MTELAPKQITYCGVCTWPLEFCEFGISLPRCQSWLASKHPELFSTVYPNTPNPESVSASAPSADELASKLELATLSSDPKEAKIQAELLKKQAKHQLKQEKELTKKQNSKIIIKRIERNKRKHIISISGLEVFQIEPKKLAKTFASKFATGASVVKNAEKLDEVVVQGDVSDEAKEYIEKLLKEQEGLENVKVEPS
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_HALMA
Sequence: MADDRHGIDDIDGETLDAVAEALRTAETAVALTGAGVSTASGIPSFRGDDGIWERHDPADFHRRRLDADPAGFWADRLSLREAIYGDIDPEPNAAHEALAALEADGHLDAVLTQNIDGLHDAAGTDRVVELHGTHRRVVCDDCGHRRDAEVVFEQAAESSDLPPRCDCGGVYRPDVVLFGEPMPDVAMNEAQRLARDSDVFLAVGSSLSVQPASLLPKIAAEGDSTLVVVNYEETPRDASAAHVLRADVTQVLPAIVERL
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.  Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK5B_BLADU
Sequence: GGESSNEAKGMWFGPRL
What is the function of this protein?
Myoactive.
What are the official names of this protein?
Pyrokinin-5b, BlaDu-Capa-PKb, FXPRL-amide.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF2_CYACA
Sequence: MQDILNIYLSSEESGGLFDFDATLPLMASQFLLIMLILDITFYKPINKVLKDRENYILKTLESATQISEKTKETLARYEEVILKSKKESQQLIDSIKTKTEHDIVNELIQTQNSTREFISKSIKELYRKKEQTLKVLEEDTENLSDKIYLKLINPKQ
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
What are the official names of this protein?
ATP synthase subunit b', chloroplastic, ATP synthase F(0) sector subunit b', ATPase subunit II.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HCP_BURA4
Sequence: MFCYQCEQTDRTGARPGCASAKGNCGKDSTTADLQDLLVHAVKGIAQYGAIARTMGVPDREAERFVLYAMFTTLTNVNFHAARFVALLREAAQTRDRVKAACEAHARAAGTAVPVLHGPAEWQPADDLAGLLKQAASVGIDAGLDTVGADIVGLRALVLYGLKGVCAYAHHAQVLGYERDDIYEGVDAALAFLAGNPADVDALLAHALDLGRLNLTVMELLDNANTGRFGVQQPSAVRVSPVAGKAILVSGHDLGDLHALLEQTAGTGIQVYTHGEMLPAHAYPSLKAFPHLAGNYGGAWQDQQSDFARFPGPILMTSNCIIEPLPQYRQRIFTTGPVGWPGVRHLEHHDFPTLIRAAQALPGFQATAPEQTITVGFGRHAVLGVADKVIDAVKAGQIRHFFLIGGCDGAAPGRNYYTEFAEQAPDDTVVMTLGCNKYRFNRHAFGDIGGIPRLLDIGQCNDSYSAIRIATALADAFECGVNDLPLSLVISWFEQKAAAVLLTLLALGIRNIRLGPTLPAFVTPGVLAVLVDQFGIQPIGDAGADLAAALARRAA
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDAC1_DROME
Sequence: MQSHSKKRVCYYYDSDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATADEMTKFHSDEYVRFLRSIRPDNMSEYNKQMQRFNVGEDCPVFDGLYEFCQLSAGGSVAAAVKLNKQASEICINWGGGLHHAKKSEASGFCYVNDIVLGILELLKYHQRVLYIDIDVHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNIPLRDGMDDDAYESIFVPIISKVMETFQPAAVVLQCGADSLTGDRLGCFNLTVKGHGKCVEFVKKYNLPFLMVGGGGYTIRNVSRCWTYETSVALAVEIANELPYNDYFEYFGPDFKLHISPSNMTNQNTSEYLEKIKNRLFENLRMLPHAPGVQIQAIPEDAINDESDDEDKVDKDDRLPQSDKDKRIVPENEYSDSEDEGEGGRRDNRSYKGQRKRPRLDKDTNSNKASSETSSEIKDEKEKGDGADGEESTASNTNSNNNSNNKSDNDAGATANAGSGSGSGSGAGAKGAKENNI
What is the function of this protein?
Catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (PubMed:11571273, PubMed:28245922, PubMed:12408863).  Histone deacetylation may constitute a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (PubMed:11571273, PubMed:8955276, PubMed:15545624, PubMed:15306652).  For instance, deacetylation of histone H3 may be a prerequisite for the subsequent recruitment of the histone methyltransferase Su(var)3-9 to histones (PubMed:11571273).  Involved in position-effect variegation (PEV) (PubMed:11571273).  In the larval brain, part of a regulatory network including the transcriptional repressors klu, dpn and E(spl)mgamma-HLH which is required for type II neuroblast self-renewal and for maintaining erm in an inactive state in intermediate neural progenitors (INP) (PubMed:28245922).
What are the official names of this protein?
Histone deacetylase HDAC1, HD.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: APOE_TAPTE
Sequence: MKVLWAALVVTLLAGCQADVEPEPEVQLGNEWAKWQAGQPWEQALGRFWNYLRWVQTLSDQVQEELLSTQATQELTALMEETMKEVKTYKAQLEQQLGPTAQETQARVSKELQAAQARLGADMEDVRNRLVQYRSELQAMMGQSTEELRGRLNSHLRKLRKRLLRDAEDLQKRLAVYQAGIREGAERSVNTLRERLRPLVEQAATVRSLISKPLQERAEAWGQRLRGRLEKVGTQAGDRLDEVREQVQEVRAKVEEQANQMRLQAEAFHARLKSWFEPLVQDMQQKWAELVEKVQLAVGTSPTSESSEKQ
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: ARCH_PYRFU
Sequence: MRQWEHYEHTADIGIRGYGDTLEEAFEAVALALFDVIVNVRKIEKKVEIDIEVEGEDLESLLYSFLEELLYLHDIEGLVFGDFKVKIEQKDGKYILRGKAYGEKFDPEKHEPKEEVKAITYHDMKIERLPDGRWMAQLVPDI
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: CAPSD_AMVST
Sequence: MSSSQKKAGGKAGKPTKRSQNYAALRKAQLPKPPALKVPVAKPTNTILPQTGCVWQSLGTPLSLSSFNGLGVRFLYSFLKDFTGPRILEEDLIYRMVFSITPSHAGTFCLTDDVTTEDGRAVAHGNPMQEFPHGAFHANEKFGFELVFTAPTHAGMQNQNFKHSYAVALCLDFDAQPEGSKNPSYRFNEVWVERKAFPRAGPLRSLITVGLLDEADDL
What is the function of this protein?
Capsid protein.  Binds to the to the 3' end of the nonpolyadenylated viral RNA and is involved in viral RNA translation initiation.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the alphamovirus/ilarvirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: PDR18_YEAST
Sequence: MECVSVEGLDSSFLEGQTFGDILCLPWTIIKGIRERKNRNKMKIILKNVSLLAKSGEMVLVLGRPGAGCTSFLKSAAGETSQFAGGVTTGHISYDGIPQKEMMQHYKPDVIYNGEQDVHFPHLTVKQTLDFAISCKMPAKRVNNVTKEEYITANREFYAKIFGLTHTFDTKVGNDFISGVSGGERKRVSIAEALAAKGSIYCWDNATRGLDSSTALEFARAIRTMTNLLGTTALVTVYQASENIYETFDKVTVLYAGRQIFCGKTTEAKDYFENMGYLCPPRQSTAEYLTAITDPNGLHEIKPGFEYQVPHTADEFEKYWLDSPEYARLKGEIQKYKHEVNTEWTKKTYNESMAQEKSKGTRKKSYYTVSYWEQIRLCTIRGFLRIYGDKSYTVINTCAAIAQAFITGSLFYQAPSSTLGAFSRSGVLFFSLLYYSLMGLANISFEHRPILQKHKVYSLYHPSAEALASTISSFPFRMIGLTFFIIILYFLAGLHRSAGAFFTMYLLLTMCSEAITSLFQMVSSLCDTLSQANSIAGVVMLSIAMYSTYMIQLPSMHPWFKWISYILPIRYAFESMLNAEFHGRHMDCGGTLVPSGPGFENILPENQVCAFVGSRPGQSWVLGDDYLRAQYQYEYKNTWRNFGIMWCFLIGYIVLRAVFTEYKSPVKSGGDALVVKKGTKNAIQRSWSSKNDEENLNASIATQDMKEIASSNDDSTSADFEGLESTGVFIWKNVSFTIPHSSGQRKLLDSVSGYCVPGTLTALIGESGAGKTTLLNTLAQRNVGTITGDMLVDGLPMDASFKRRTGYVQQQDLHVAELTVKESLQFSARMRRPQSIPDAEKMEYVEKIISILEMQEFSEALVGEIGYGLNVEQRKKLSIGVELVGKPDLLLFLDEPTSGLDSQSAWAVVKMLKRLALAGQSILCTIHQPSATLFEQFDRLLLLGKGGQTIYFGEIGKNSSSVIKYFEKNGARKCQQNENPAEYILEAIGAGATASVQQNWPDIWQKSHEYANINEKINDMIKDLSSTTLHKTATRASKYATSYSYQFHHVLKRSSLTFWRNLNYIMAKMMLLMISGLFIGFTFFHVGVNAIGLQNSLFACFMAIVISAPATNQIQERATVAKELYEVRESKSNMFHWSLLLITHYLNELPYHLLFSTIFFVSSYFPLGVFTEASRSSVFYLNYAILFQLYYIGLALMILYMSPNLQSANVIVGFILSFLLSFCGAVQPASLMPGFWTFMWKLSPYTYFLQNLVGLLMHDKPVRCSKKELSLFNPPVGQTCGEFTKPFFEFGTGYIANPDATADCAYCQYKVGDEYLARINASFSYLWRNFGFI
What are the official names of this protein?
ABC transporter ATP-binding protein/permease PDR18, Pleiotropic drug resistance protein 18.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SINL3_ARATH
Sequence: MENITNNSERSLDRPKRQRPVSMENVGGTASGSEVARSATLLELDLLDCPICYHKLGAPIYQCDNGHIACSSCCKKVKYKCPYCSLRIGFFRSRILEKIVEAVVVSCPNAKYGCTEKIPYDNESESAHERVCEFTLCYCPEPECKYTGVYTDLYRHYHAEHKTDHSWFKCGEYNNAWLHVTGEKLSFLVLQEYEDGPLVVVQCSMESHGICVTVNCIAPCAPGVGEFSCHLIYRNGSEKITFESKKMNKIQKVSPENHVANYKPIPYYLRGEASNFMSIPYYLLDEASILKMQICIRRSGEEV
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  It probably triggers the ubiquitin-mediated degradation of different substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase SINA-like 3, RING-type E3 ubiquitin transferase SINA-like 3, Seven in absentia-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
Protein: RL27_META1
Sequence: MAHTKAGGTTRNSRDSAGRRLGVKATDGQFVNAGSIIYRQRGTKIFPGNNVGRGKDDTLFALISGIVKFEDRINRKFASVYAVEDLKAKK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS20_CHLT3
Sequence: MPQHKSAEKRVRQSKRRNARNRVHKAEMKKLVKTVKGLIEKSAEKEEVENAYRAAIQKLDRMAVKGYLHKNNASNKKSKLSKLVNRFSKGDAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: PGSA_YERPS
Sequence: MQLNIPTWLTLFRVVLIPFFVLAFYLPFVWAPMVCAIIFVFAAATDWFDGFLARRWKQTTRFGAFLDPVADKVMVAVALVLVAEHYHSWWITLPAATMIAREIIISSLREWMAEIGKRSSVAVSWVGKVKTMAQMGSLVGLLWRPDHNVELASFVLLYIAAVLTFWSMFQYLNAAWSDLLEP
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPIA_HELPJ
Sequence: MKPIKTYDIKEEELAKTAYATIKTNKGNITLELFYKDAPQAVSNFVTLAKEGFYNGLNFHRVIAGFVAQGGCPYGTGTGGPEHRIKCEVAHNPNKHQRGSISMAHAGRDTGGSQFFLCFVDLPHLDGEHTVFGKITSAESLSVLDKIKQGDIIESVVFSPSL
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
Protein: SLYD_ECOL6
Sequence: MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISGLETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQGPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHHDHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH
What is the function of this protein?
Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step.  This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity (By similarity).
What are the official names of this protein?
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD, PPIase, Metallochaperone SlyD.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: HISX_BURMA
Sequence: MAIKIRKLDSAGEGFAAELRAVLAFEASEDDAIERAVAQILADVKARGDAAVLDYTNRFDRLNAASVAALELPQSELEAALEGLEPKRRAALEAAAARVRGYHEKQKIECGSHSWQYTEADGTVLGQKVTPLDRVGLYVPGGKAAYPSSVLMNAIPARVAGVGEIVMVVPTPDGLKNDLVLAAALLGGVDRVFTIGGAQAVAALAYGTQTVPAVDKICGPGNAYVASAKRRVFGTVGIDMIAGPSEILVLCDGTTDPSWVAMDLFSQAEHDELAQSILLCPDEAFIERVEKAIGELLPTMPRQDVIRASLEGRGALVKVRDMAEACRIANDIAPEHLEISALEPHQWGKQIRHAGAIFLGRYTSESLGDYCAGPNHVLPTSRTARFSSPLGVYDFFKRSSLIEVSAEGAHTLGEIASELAYGEGLQAHAKSAEYRMKGAGDRQKG
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: AAC32_SALSP
Sequence: MHTRKAITEAIRKLGVQTGDLLMVHASLKAIGPVEGGAETVVAALRSAVGPTGTVMGYASWDRSPYEETLNGARLDDKARRTWPPFDPATAGTYRGFGLLNQFLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLGAPLNSVTALHYAEAVADIPNKRWVTYEMPMLGRNGEVAWKTASEYDSNGILDCFAIEGKPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGATPIVPAHEAAQRSCEPSG
What is the function of this protein?
Resistance to antibiotics containing the 2-deoxy-streptamine ring including gentamicin, kanamycin, tobramycin, neomycin and apramycin.
What are the official names of this protein?
Aminoglycoside N(3)-acetyltransferase III, ACC(3)-III, Aminocyclitol 3-N-acetyltransferase type III, Gentamicin-(3)-N-acetyl-transferase.
What is the protein family that this protein belongs to?
Belongs to the antibiotic N-acetyltransferase family.
Protein: PURQ_RUEST
Sequence: MKAAVVVFPGSNCDRDLAVAFEQAGFDVSMVWHKDSELPEGVDIVGVPGGFSYGDYLRCGAIAAQSPICKAVVAHAERGGYALGVCNGFQILTETGVLPGALLRNAGLKYICKTVDLAVATSDSAFTQGYNAGDVIGVPIAHHDGNYYADDATVQMLKDQDRVAFTYVDNPNGSVADIAGILSENRRVLGMMPHPERAADEGHGGTDGVAMFRALSGLLTDA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_LEVBA
Sequence: MSVKIRLKRMGSKKRPFYRVVVADSRSPRDGRFIEQVGTYNPVTEPAQVTLKEESILNWLNNGAQPSDTVKTLLSNAGIMKQYHEAKYTKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: Y1629_PSELT
Sequence: MYGLINIGFGNVISGDRVIAIVNPESAPLKRLKDEAKDEGKLIDATYGRKTRAILITDSNHIILSAIQPETIAQRFKQSMIEIEENLNKVR
What are the official names of this protein?
Putative regulatory protein Tlet_1629.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: PROB_BACC2
Sequence: MKKQRIVVKIGSSSLADSHGGISTEQLSDHVAALARLKEEGHEVVLITSGAVAAGFSALGYPSRPVTIKGKQAAAAVGQSLLMQAYTEEFRKYGIVTAQLLLTRSDFSRKEQYSNAYATLGELLNRSALPIINENDSISLEELTFGDNDMLSALVSGLVSADMLMIFTDVNGLYDKNPQKNADAKKYYFLPEVTEEISSLAGDAGSKLGTGGMKSKIDAAKTALSLGVSVFIGTGRGQEKFVDVLKGKGDGTYVGNAPQKEMKMNKQWIALHSLVSGQIEVDAGAATAIIQHGKSLLPAGVTNVSGFFQVGEVVEVVTQQGRVIGKGQCTYSAEELRDVKGMQSQDIQVRGERHSYEVIHRDHWVSL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_BORRA
Sequence: MGQKVHPYSLRIKINRDWKSKWYFDKKLYSEILHEDFLIRRETMKFLKGIKFDISDIEIIRNNLQRVTVVISTPRPGSVIGVKGANLEKIGQLLTRKVSKKINIKIKEIKKPEFDAQIVANGIAKQLENRASYRKLLKSSLLSSISKGIQGIKIKVSGRLGGAEIARSFEVKEGRIPLHTLRANIDYGFAEAYTTYGVIGVKVWLFKGEILGKQINSDAGQVINRKPSKDKVERFDKGKIDDKGRKVVNDDKFSREKLEIGSRSKNDFKNKNDSDI
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.