PharMolix/UniProtQA huggingface dataset:
Protein: YDJC_VIBC1
Sequence: MKVIFNADDFGLTQGVNNGIIKAHQQGVVLSTTMMMGMDAEQHAVELANQNPNLKIGVHLRFTAGNPLTGHPNLTGGGEQFVRFNELWKKRDFQEEAVYQEAVAQVERFLSLGLPLSHIDSHHHAHTHPQLLPVIRRVAEQYRVPLRGSGLCHIDCDTTYHFTDEFYDQGVSLDGVMAHLKSLKSQYDVVEVMCHPADVDQHLLSISGYALLRELELQVLTSPILKQELAEHGMSITDYSTLISTRKFASV
What is the function of this protein?
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
What are the official names of this protein?
Carbohydrate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family.
Protein: LAP1_ASPCL
Sequence: MRVLAAIALGATGLRGALAAVVPQEVLGTNPHIHHEQEKYLIELAPYQTRWVTEEEKWALKLDGVNFIDITEEHNTGFYPTLNSASYVKYPLKMQYADEVVALNKNLSTANMKANLEHFTSFHTRYYKSQTGIESATWLASQVEKVITESGAANHGATVERFAHPWGQFSIIARIPGQTNKTVVLGAHQDSINLFLPSILAAPGADDDGSGTVTILEALRGLLQSGSVAQGNATNTIEFHWYSAEEGGMLGSQAVFSSYKKNRREVKAMLQQDMTGYTKGALDAGAKEAVGIMIDYVDQGLTRFVKEIVTTYCSLGYVETKCGYACSDHTSASKYGYPAAMATESEMENTNRKIHTTDDQIKYLSFDHMLEHAKLTLGFAYELAFAPF
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KLRG2_MOUSE
Sequence: MEPPQVPAEAPQPRASEDSPRPERTGWEEPDAQPQELPEKSPSPALSGSPRVPPLSLGYGAFRRLGSCSRELPSPSPSWAEQPRDGEAELEPWTASGEPAPASWAPVELQVDVRVKPVGAAGASRAPSPAPSTRFLTVPVPESPAFARRSAPTLQWLPRAPSPGSTWSRGSPLAANATESVSPAEGCMVPPGSPACRCRCREPGLTKEDDALLQRAGIDGKKLPRAITLIGLPQYMKSLRWALVVMAVLLAVCTVAVVALASRGGTKCQPCPQGWMWSQEQCYYLSEEAQDWEGSQAFCSAHHATLPLLSHTQDFLRKYRITKGSWVGARRGPEGWHWTDGVPLPYQLFPADSEDHPDFSCGGLEEGRLVALDCSSPRPWVCARETK
What are the official names of this protein?
Killer cell lectin-like receptor subfamily G member 2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MNME_BURP0
Sequence: MLATDSDPIVAIATASGRGGIGVVRLSLGRAGEAAARALSDALCGARLMPRHASYVPFLDGAGEPLDRGIALYFPAPHSYTGEHVIELQGHGGPIVLQLLLQRCLDAGRAHGLRLAEPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAGRSLDGAFSRDIHALVDDVIALRMLVEATLDFPEEEIDFLEAADARGKLAHIRERLAHVLGDARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDKVAQTIQIEGIPLHIIDTAGLRETEDEVEKIGIARTWGEIERADVVLHLLDARSGLGPGDEAIAARFPDGVPVVRVLNKTDLTGAPASVTRTGGGAARADVCEVRLSAKRGDGIDLLRGELLRIAGWQAGAESVYLARERHLIALRAAQAHLARAAEHAEQNAQALDLFAEELRLAQERLNSITGEFTSDDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_VIBVU
Sequence: MATINQLVRKPRAKQVVKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGALDCAGVNNRKQGRSKYGVKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: CMR1_ASPFU
Sequence: MGADNELSEFEKQRLANIAERDALLKKLSLDAQSSGLFPPKSARSSPGGQTKPKKKPPPKKVKKEDEHPVPRRMSSRLRGLAADSEVAKRKADEQYEAAQQAERAKRVRKSDAFSFSEMLVSGQKLSGDSLIGVDVVTKGVAMPYQRTFGDEDIKKTTDKELKALREEMSGLRLWEAWEPNRIKLTPERIYTMTFHPSEAKPLIFAGDKMGNLGVLDASQEKPTSAVKQEDDEDAEDDDPDPVLTTLKPHTRTISSLHIHPSKPTHLYSASYDSSIRELDLEKTTSVEKYAPESTSDDIPISGIDMAPDDPNTLYWTTLDGAFGRYDTRASRRSAVATWQLSEKKIGGFSLFPTHPHFFATASLDRTMRLWDIRKLSHDDPVPVGEHVSRLSVSHAAFNSAGQIATSSYDDTLKIYDFGSKGIAAWEPGYTLSDAEMKPDTIVRHNCQTGRWVTILRPQWQANPQSSIQRFCIGNMNRFVDVYSSSGDQLAQLGGDGITAVPAVAVFHRSTNWIAGGTASGKICLWM
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein cmr1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: FAR1_PROCL
Sequence: NRNFLRF
What is the function of this protein?
Increases the rate and amplitude of spontaneous contractions of semi-isolated hearts.  Increases the amplitude of excitatory postsynaptic potentials in abdominal extensor muscle.
What are the official names of this protein?
Cardio-excitatory FMRFamide homolog NF1.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROK_SHEAM
Sequence: MAEKRNIFLVGPMGAGKSTIGRHLAQMLHLEFHDSDQEIESRTGADIAWVFDVEGEEGFRRREAQVIADLTEKQGIVLATGGGSVQSKDIRNYLSARGIVVYLETTIDKQVARTQRDKRRPLLQVDDPRSVLETLAESRNPLYEEIADVIVKTDDQSAKVVANQIIEQLGF
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_CROS8
Sequence: MSNKDQILTSPYLQFNRSQWAALRDSVPMTLTEGEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNAVLKERNLMKKKGFPQSYDMHRLVKFVSDIKSGVPNVTAPVYSHLIYDVIPDGDKVVNQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQRWYINRFLKFREGAFTDPDSYFHHYAKLSEDEAVNIATQLWKEINWLNLKENILPTRERASLIMTKSANHAVDCVRLRK
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_HALH5
Sequence: MKEKLVAIVGPTAVGKTKTSVMLAKRLNGEVISGDSMQVYRGMDIGTAKITAEEMDGVPHHLIDIKDPSESFSVADFQDLATPLITEIHERGRLPFLVGGTGLYVNAVIHQFNLGDIRADEDYRHELEAFVNSYGVQALHDKLSKIDPKAAAAIHPNNYRRVIRALEIIKLTGKTVTEQARHEEETPSPYNLVMIGLTMERDVLYDRINRRVDQMVEEGLIDEAKKLYDRGIRDCQSVQAIGYKEMYDYLDGNVTLEEAIDTLKRNSRRYAKRQLTWFRNKANVTWFDMTDVDFDKKIMEIHNFIAGKLEEKSK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RRF_SYNWW
Sequence: MIKDILSDTEERMKKTIEHLRKDLASLRAGRANPAMLEKIMVDYYGQPTPINQLANITVPEARLLVIQPWDKTIIASIEKAIMKSDLGINPSNDGNVIRLVIPQLTEERRKELVKVLRKRAEEARVAVRNIRRDSNELLKSGEKEKLISEDDNKKGMDDIQKETDRHIKEIDSILQGKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHED_HYDCU
Sequence: MQKSVDPAEGITTYKILPGEFYVTKDNERIETVLGSCISACVRDPVTGVGGMNHFMLPVDKNATGASELSDANRYGNYAMENLVNALLNAGARRERLEFKLFGGGRIMSSTTNIGWYNIGFAFDYIYTEGFKIVSQDIGDVYPRKILYYPNSGRVRVRRLNAMHNQSLAAEESRYINNIGSKPVEGDVELF
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: NRDR_STRPJ
Sequence: MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERVEERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENEIQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GLK_CHRSD
Sequence: MTRPALIGDIGGTNARFALVTPGAFDLHDIRTLPCAHYPSLSDAIRAYLKEVGAEMPTEACLAFACPVHDDEVRMTNNAWRFSKRQVAEEFGFTLFKVINDFTAQALGVPHVADDELVALGDGEAAPGCTRLIFGPGTGLGMAGLFPGQHDWIPLPTEGGHISFAPTDQHERDLLAYFQARYGRVSVERILCGQGLLDLYRAHAQLAKQVARYNTPAEVTGAARAGDPLARNALERFLKILGDVSGDAALMLGARGGVYLCGGILPRLLDWLPHSHFRDAFADKGRMHAYTAHIPVWVVTAPWNGLLGACEALHNEEVT
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLRD_ASPNG
Sequence: MKRSALLASFLPLALGCDSAETHSCASAFSVSSAAAASFCATFTASTVTATTGVPDVFLSNCDYKTKHLSSACSCLGTADGSAPASTPAAPAVSSSSKVGKAPAVAATRTSAIPTTFHTTAVRVPLSTSAAAAVTSQAVLPAQSSVAGNGGTTCTVTEYASISSAVASCSNILLSNINAPASSTIDLTGLQTGAAVIFAGETTFGDTYDSDFDPIVISGTDVTITGEEGHVINGNGEAYWDGEGSNGGQDKPDHFIVVKDMYNSKIENLNILNWPVHCFEIENTEYLTISGLILNNTAGDAANSKSDGDPAAHNTDGFDIKQSDFLTLSNSWVHNQDDCVAVTSGSSIVVDNLYCYGGHGLSIGSIGGKSNNTVDGVTFSNSQVINSENGCRIKSNADTTGEVYNVKYENITLSGISDYGIDIQQDYENGGATGDPTNGVKIENISFVNVKGTMSDGKDYYILCGDGSCSNFVFTDVDITGGSDDSCNYPSSGCP
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase D, PGD, Pectinase D, Polygalacturonase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: T150A_MOUSE
Sequence: MTAWILLPVSLSAFSITGIWTVYAMAVMNRHVCPVENWSYNESCSPDPAEQGGPKSCCTLDDVPLISKCGTYPPESCLFSLIGNMGAVMVALICLLRYGQLLEQSRHSWINTTALITGCTNAAGLVVVGNFQVDHAKSLHYIGTGVAFTAGLLFVCLHCVLFYHGATTPLDMAMAYLRSVLAVIAFITLVLSGVFFLHESSQLQHGAALCEWVFVLDILIFYGTFSYEFGTISSDTLVAALQPAPGRACKSSGSSSTSTHLNCAPESIAMI
What is the function of this protein?
Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex.  Acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis (By similarity).  May also play a role in fasting-induced catabolism (By similarity).
What are the official names of this protein?
Transmembrane protein 150A, Transmembrane protein 150.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localizes mainly at the plasma membrane; only a minor fraction localizes on intracellular structures.
Protein: PGK_SHEPA
Sequence: MTILNMKDLDLQGKRVLIREDLNVPVSDGVVTSDARLRASLPTIKLALEKGAAVMVMSHLGRPTEGEFNAEFSMQPVVDYLTKALDCPVRLAADYLDGIEVAVGEVVVFENVRFNLGEKKNDEALAKKMAALCDVYVMDAFGTAHRAQASTHGVGLHAPIACAGPLLAGELEALGKALDNPARPMVAIVGGSKVSTKLTVLESLSTKVDQLVVGGGIANTFVAAAGHKVGKSLYEADLIEEAQRLVANAQSRGGDIPVPTDVVVAGEFSPTATATLKDVSDVSDTDMIFDIGPDSAEALAEIIKNAGTVVWNGPVGVFEFDQFGEGTKRIAQAIAESNAFSIAGGGDTLAAVDKYGIADKVSYISTGGGAFLEFLEGKELPAVAMLESRGQ
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAIA_ECO7I
Sequence: MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
What is the function of this protein?
Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA.
What are the official names of this protein?
Crotonobetainyl-CoA reductase, Crotonobetainyl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYOD1_MOUSE
Sequence: MELLSPPLRDIDLTGPDGSLCSFETADDFYDDPCFDSPDLRFFEDLDPRLVHMGALLKPEEHAHFPTAVHPGPGAREDEHVRAPSGHHQAGRCLLWACKACKRKTTNADRRKAATMRERRRLSKVNEAFETLKRCTSSNPNQRLPKVEILRNAIRYIEGLQALLRDQDAAPPGAAAFYAPGPLPPGRGSEHYSGDSDASSPRSNCSDGMMDYSGPPSGPRRQNGYDTAYYSEAARESRPGKSAAVSSLDCLSSIVERISTDSPAAPALLLADAPPESPPGPPEGASLSDTEQGTQTPSPDAAPQCPAGSNPNAIYQVL
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation (PubMed:16901893).  Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis.  Induces fibroblasts to differentiate into myoblasts.  Interacts with and is inhibited by the twist protein.  This interaction probably involves the basic domains of both proteins (PubMed:21798092, PubMed:3175662).
What are the official names of this protein?
Myoblast determination protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLU_LAWIP
Sequence: MNELTPREIVVELDKYIIGQEQAKRMVAIAVRNRWRRQQLQEGLRDEVAPRNIIMIGPTGVGKTEIARRLAKLCHAPFIKVEATKYTEVGYVGRDVESMIRDLMEISINLVRKEEAEKVRERAEVLAEERLLDLLLPIGENRDATREKLRSLFRQGHLKDREVDIEVQEQTQPIGILNVPGMEQIGNQMKDAFSRIFPQKTHRRKMKVSAAWEHLVGEESNRLVDNDKLTDLARERVEQMGIVFIDEIDKLASASQHRSSDISREGVQRDLLPIVEGSAVNTKYGLIKTDHILFIAAGAFHLSKPSDLIPELQGRFPLRAELEALGKNEFYRILTEPDNALTRQYEALLETEGVKIVFTDDGLKEISAFAEDVNTQTENIGARRLHTIMEKILADISFDAPEKFGTTLEVTKEYVVSYLEDIRANTELSRFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APC5_RAT
Sequence: MMTNGVVHANLFGIKDWVTPYKIAVLVLLNEMGRTGEGAVSLVERRKLNQLLLPLLQGPDITLSKLYKLIEESCPQLANSVQIRIKLMAEGELKDLEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMDREDGERQMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQAALLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFDRLILTGAEGKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRADSYVLLEHSVKKAVHFGLPRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSTMALQQAQMLLSMNSLESLSAGVQQNNTESFAVALCHLAELHAEQGCFAAAGEVLKHLKERFPPNSQHAQLWMLCDQKIQFDRAMNDGKFHLADSLVTGITALNGIEGVYRKAVVLQAQNQMTEAHKLLQKLLTYCQKLKNTEMVISVLLSVAELYWRSSSPTIAMPVLLEALALSKEYRLQYLASETVLNLAYAQLILGIPEQALTLLHMAIEPILADGAILDKGRAMFLVSKCQVASAASYDPVKKAEALEAAIQNLTEAKNYFAKVDCRERIRDVSYFQARLYHALGKTQERNHCAMVFRQLHQELPSHGVPLINHL
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5.
What is the protein family that this protein belongs to?
Belongs to the APC5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: YOBD_ECOL6
Sequence: MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADK_COXB1
Sequence: MLKIVSKPSFNRIALMGREGVEGVPETLAALKDYLVSLNREVILEENAAHMIDGSRLLTVPANDLKKKADLLIVVGGDGSLLNAAHIAVPQQLPVLGINRGRLGFLTDIPPNELTQISDILDGHYREEVRFLLEGTVEEGDEIVAQGIALNDIVLLPGNAPKMIEFDIFINDEFVCNQRADGLIITTPTGSTAYALSGGGPILHPQLNAMALVPMFPHTLSSRPIVVDAESQIKITISPENDVSPYVSNDGQERVSIKPGGNVYTRKYHYPLHLIHPTDYNYYGTLRRKLDWEKRAAKV
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL1_ASPFL
Sequence: TPSQCTAAQANKCCTGLTNGILNLNVLPALNP
What are the official names of this protein?
Allergen Asp fl 1, Allergen Asp l 1.
Protein: VDAC_DICDI
Sequence: MNPGLYADLTKPTADFIKKDFAETFKLDTTFKGKYGSIVAVTDIKDSGVVASIQPKADFTKYLGKVSNGNFTVDTNGVKKGEFTIENIIPGLKAVANGDSKQNFSTEFQYKKDKIAFTLFGHNNKSFNTSLAFLINPTFSVGVQAEGNAKNTLKNVNATITIRPRPDVFVSIVDRFMDKQILLSTLYTATSKLSFAGDVTVDLKASEKAPSFNVGTQYKIDSASLLKAKVNNNRKVNISYIYNTSNNTKFVLGWNVNTKNFKQGNTFGATVNLTL
What is the function of this protein?
Forms a channel of about 1,7 nM through the cell membrane that allows diffusion of small hydrophilic molecules.  The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 20 mv.  The open state has a weak anion selectivity whereas the closed state is cation-selective.
What are the official names of this protein?
Mitochondrial outer membrane protein porin, Voltage-dependent anion-selective channel protein, VDAC.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic mitochondrial porin family. Highly divergent.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: YO16W_YEAST
Sequence: MFAKLYRGLTYVTNKILSTLLSHHSIHYCINSFKPTTLAIIILLHPCCRCNVYIIRCIHH
What are the official names of this protein?
Uncharacterized protein YOL164W-A.
Protein: MPK17_ORYSJ
Sequence: MGGRARSILRWLRHHRSRRVSSSSFHLTTTGDDTVKDLHDPRREDAEGDGWEEVHEGPESDPEEYIALVSEDAGTHLPVRTEPRRMDPSKKEPDFFTEYGEANRYKVSEVIGKGSYGVVAAAVDTQTGERVAIKKINDVFDHVSDATRILREIKLLRLLRHPDIVEIKHIMLPPSRREFRDIYVIFELMESDLHQVIKANDDLTPEHHQFFLYQLLRGMKYIHAASVFHRDLKPKNILANADCKLKVCDFGLARVSFNDTPSAIFWTDYVATRWYRAPELCGSFFSKYTPAIDIWSVGCIFAELLTGKPLFPGKNVVHQLDLMTDLLGTPSAESLAKIRNEKARRYLSNMRKKPRVPFTKKFPGVDPMALHLLERLLAFDPKDRPSAEEALTDPYFNGLANSEREPIAQPISKLEFEFEKRKLAKDDVRELIYREILEYHPHMLQEYLRGGDQMSFMYPSGVDRFKRQFAHLEEGVSKGEKSSPQLRQNASLPRERAIGNKHGDDEYHAKLNVGEKPCHASVTDGISKPLMSARSLLKSESISASKCIGEKPKQDRDQEDSLTESMDETADEVSEKVAQLKT
What are the official names of this protein?
Mitogen-activated protein kinase 17, MAP kinase 17.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: ATPL_SYNY3
Sequence: MDSTVAAASVIAAALAVGLGAIGPGIGQGNASGQAVSGIARQPEAEGKIRGTLLLTLAFMESLTIYGLVIALVLLFANPFA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: KLOT_MACFA
Sequence: MPASAPPRRPRPPPPSLSLSLLLVLLGLAGRRLRAEPGDGAQTWARFARPPAPEAAGLFQGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRIANVPSGAPSPLQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINPRRMTDHSIKECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKKFIKGTADFFALSFGPTLSFQLLDPHMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQEKTLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGIVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAAIQPQITLLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMVSELVRVNITPVVALWQPVAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRNNFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDRTAPRFGLYRFAADQFEPKPSMKHYRKIIDSNGFPGPETLEKFCPEEFTVCTECSFFHTRKPLVAFIAFLFFAFIVSLSLIFYYSKKGRRRYQ
What is the function of this protein?
The Klotho peptide generated by cleavage of the membrane-bound isoform may be an anti-aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling.
What are the official names of this protein?
Klotho.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family. Klotho subfamily.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. Apical cell membrane; Single-pass type I membrane protein. Note=Isoform 1 shedding leads to a soluble peptide. SUBCELLULAR LOCATION: [Isoform 2]: Secreted. SUBCELLULAR LOCATION: [Klotho peptide]: Secreted.
Protein: D7_XENLA
Sequence: MEFDELMQCPYDKNHMIRPSRFPYHLVKCRENNRAAAKILATCPYNARHRVPKQELDLHMASCEYRVTMEPISAAFSHQKVETSTWQSPPCEEVWETDEDPVSRPKPFILNDFTPSQPFNMSEGDGNMPYTGISSNYRPEVQPMNSVMQVKQNQPEPEPFTSSERNYDPRSKEPPNPKQPAVNGYKPATTNTNPWCRQTGGSRGAAPPKLGAKSSDEGPRNKEFPTPKANLMNEYVPVAANANPWCRQPGGSSAASEPLGVDSFDEWPCLGRQPWVRK
What is the function of this protein?
Involved in oocyte maturation.  It is possible that D7 is required at a certain point in the maturation process and that maturation cannot proceed beyond this point unless a threshold amount of D7 protein is provided.
What are the official names of this protein?
Protein D7.
What is the protein family that this protein belongs to?
Belongs to the UPF0224 (FAM112) family.
What are the subcellular locations of this protein?
Cytoplasm.