PharMolix/UniProtQA huggingface dataset:
Protein: TO4AB_XENLA
Sequence: MEESESQAPVPPHGISLVSSPVRAVIRIRRKIRTMKKSRLQVDLTGERSLDSAKASLRRQISMDRASLFKSSTYEKQQYFNFDTPTLEKLALTSQIRKRNRNKSRHVLYPGNVRKCLPVEQKSKAKRCLLLFVGIVCFQIFNAIENLDDNLQKYDLDGLEKTLQREVFGQTRAIEKLMDHLKDYLATHYHNKPLVLSFNGPSGVGKSHTGRLLAKHFRSVVDNDFVLQYYTNHNCPNESDVIQCQAEVSAMISQMISRAEIEEKIPVFLFDEVEAMPVALLDVLHSYFQLNQSNEYLNVVYILISNIGGHEITKFVLQNVSNDFFNLPQELHQIVLSSLRKHHSLWDVAEIVPFTLLEKRHILDCFLDELLREGFYPDHSNIESLAGQLRYYIKGNKEFSISGCKQVVAKVNLLQPYT
What are the official names of this protein?
Torsin-4A-B, Torsin family 4 member A-B.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. Torsin subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ARGC_SACD2
Sequence: MIKVGIVGGTGYTGVELLRILASHPQAEVTVITSRAEAGRQVSELFPNLRGHYDLAFSEPSKEVLLECDVIFFATPHGVAQAMMAELIEGGARVIDLSADFRIRDIATWEKWYGQKHGCPDLVASAVYGLPEVNREKIKSAQLIACPGCYPTSIQLGFLPLLEKGLIDVSSLIANSASGTTGAGKQASVPNLFSEASDSFKAYGAAGHRHLPEIEQGLVDIGGEHANGLSLTFVPHLLPTIRGIHSTLYAKLKGDAGDLQALYEQRYANEPFVDVLPKGDFPQTRTVKSTNMCRISVIEPQERGTVVIMSVIDNLTKGASGQGVQNMNIMFGLDENMGMSSPAILP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_BURCM
Sequence: MTEQKRKIEKLTGVKGMNDILPQDAGLWEFFEATVKSLLRAYGYQNIRTPIVEHTQLFTRGIGEVTDIVEKEMYSFTDALNGENLTMRPENTAAVVRASIEHNMLYDGPKRLWYIGPMFRHERPQRGRYRQFHQVGVEALGFAGPDADAEIIMMCQRLWDDLGLTGIKLEINSLGLAEERAAHRVELIKYLEQFADVLDEDAKRRLYTNPLRVLDTKNPALQEIAQNAPKLIDFLGDESRAHFEGLQRLLLANNIPFKINPRLVRGLDYYNLTVFEWVTDKLGAQGTVAAGGRYDPLIEQLGGKPTAACGWAMGIERILELLKEEDLAPEQEGVDVYVVHQGETAREQAFIAAERLRDTGLDVIFHCSADGAPASFKSQMKRADASGAAFAVIFGEEEVANGTVGVKALRGAGEEGEKNVQQTVPVESLTEFLINAMVASAEDGDD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2750_GEOKA
Sequence: MKISYHGHSVVRIETNGKTILIDPFITGNTTTDLNAADVKADVILLTHGHGDHVGDTVEIAKRNNALVVATFELATYLSWQGVETFGMNIGGAREFDFGTVKFTQAFHSSGFVTDDKQIIYLGMPTGILFTAEGKTIYHAGDTGLFSDMKLIGERHNIDVAFLPIGDSFTMGPEDAAVAAEWLGAKLVVPIHYNTFPPITQDPERFVSLLPPGVGRALKPGESIEL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase GK2750.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: PEK11_ARATH
Sequence: MDKVQQQADLFGKTISPFVASQPTNVGGFTDQKIIGGSETTQPPATSPPSPPSPDTQTSPPPATAAQPPPNQPPNTTPPPTPPSSPPPSITPPPSPPQPQPPPQSTPTGDSPVVIPFPKPQLPPPSLFPPPSLVNQLPDPRPNDNNILEPINNPISLPSPPSTPFSPPSQENSGSQGSPPLSSLLPPMLPLNPNSPGNPLQPLDSPLGGESNRVPSSSSSPSPPSLSGSNNHSGGSNRHNANSNGDGGTSQQSNESNYTEKTVIGIGIAGVLVILFIAGVFFVRRKQKKGSSSPRSNQYLPPANVSVNTEGFIHYRQKPGNGNSSAQNSSPDTNSLGNPKHGRGTPDSAVIGTSKIHFTYEELSQITEGFCKSFVVGEGGFGCVYKGILFEGKPVAIKQLKSVSAEGYREFKAEVEIISRVHHRHLVSLVGYCISEQHRFLIYEFVPNNTLDYHLHGKNLPVLEWSRRVRIAIGAAKGLAYLHEDCHPKIIHRDIKSSNILLDDEFEAQVADFGLARLNDTAQSHISTRVMGTFGYLAPEYASSGKLTDRSDVFSFGVVLLELITGRKPVDTSQPLGEESLVEWARPRLIEAIEKGDISEVVDPRLENDYVESEVYKMIETAASCVRHSALKRPRMVQVVRALDTRDDLSDLTNGVKVGQSRVYDSGQYSNEIRIFRRASEDSSDLGTNTGYYPSQDYATSHEYESESRAFNTSHRNH
What are the official names of this protein?
Putative proline-rich receptor-like protein kinase PERK11, Proline-rich extensin-like receptor kinase 11, AtPERK11.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LOLA_SHEB9
Sequence: MKKRLCAVLLASPLLFSAAVFADDAQQLRDKLIGTASLKADFKQTVTDVNKKVIQTGSGIFALAYPNQFYWHLTQPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYAVTKQQDCYEIKPKAIDSGILSVKVCFKNAQLANFNVADDKGNLSQFDLSNQQAITDKDKALFSFVLPDNVDVDDQRRKTAH
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: VM2TI_ERIMA
Sequence: QRQEEPCATGPCCRRCKFKRAGKVCRVARGDWNNDYCTGKSCDCPRNPWNG
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen.
What are the official names of this protein?
Disintegrin eristicophin, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SHOC2_BOVIN
Sequence: MSSSLGKEKDSKEKDPKAPSAKEREKEAKASGGFGKESKEKEPKTKGKDAKDGKKDSSAAQPGVAFSVDNTIKRPNPAPGTRKKSSNAEVIKELNKCREENSMRLDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGPSQFSTIYSLNMEHNRINKIPFGIFSRAKVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDNPNLHSLPFELALCSKLSIMSIENCPLSHLPPQIVAGGPSFIIQFLKMQGPYRAMV
What is the function of this protein?
Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation.  Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
What are the official names of this protein?
Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein sur-8 homolog.
What is the protein family that this protein belongs to?
Belongs to the SHOC2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus upon growth factor stimulation.
Protein: PQQF_PSEPH
Sequence: MSASLFWKCSCPRRITLCPHWRPCQRLRVSLRHAPHLKRCAATLRVAAGSHDVPLAWPGLAHFLEHLLFLGTERFPVEQGLMAYVRAQGGQLNARTCERATEFFFELPASAFAGGLERLCEMLAQPRMSLEDQHREREVLHAEFIAWSRDATAQRQFALFDGLHAAHPLRAFHAGNRYSLNLPNNAFQQALQQFHREYYQAGQMVLSLAGPQPLEELRALAERYGSCLPSGQHLEQTAPPALMTTGNQTYQQLSGQRLDLLFALERLPAGATAAVDFLCTWLQSAKPGGLLAELQQRQLAHSLKATLLYEFAGQALLHLEFDLTSVAASAPVQVRELLTEWLGFFSAQADWAPLREEYVLLQQRQIEVASALELSRRDSRQAADGLDESGLAALKQVLKQLQPQAVEHFSHDWRLPPANPFLRSTIEAPRAGLIRGQTSAHRGLRTFAQDRSRGRKESSALSFSQALPADPSGSALTLRWQLASPAPMGLHARLLRSLATLRDDARQAGVELIFTSCGKDWLLKLHGLPSPMPAVLLQALKALGRPAESFWQEQASVNAEAPLLTIRQLLKAFSEQPQPDSPAQPDPEALQALWASARWDGLGLALPAAIQEALSRTLQQMPGTADATLCRPVPAGTGQQWQNLPGSAGEHALLLFYPVPSASLADEAAWRLLGQLCQTPFYQRLRVELQLGYGVFSAVRQRNGRTGLLFGVQSPGATVTEILQHIAQFLEHLPEQLQALDEPSWNDQQQALAQQLQPATLPLDQAMELLWQAKLAGHSSDYLPQLQGCIEALTPAIVIQAARQLREAAGGCSALANRPCPGTPWQVAE
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ (By similarity).
What are the official names of this protein?
Coenzyme PQQ synthesis protein F, Pyrroloquinoline quinone biosynthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
Protein: RS11_MYCPN
Sequence: MAKKKKINVSSGIIHVSCSPNNTIVSASDPGGNVLCWASSGTMGFKGSRKKTPYSAGIAADKVAKTVKEMGMATVKLFVKGTGRGKDTAIRSFANAGLSITEINEKTPIPHNGCKPPKRPR
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: MUTL_LACCB
Sequence: MPKIHQLSATLSNQIAAGEVIERPASVVKELVENSIDAQATQIDVLISAAGLQEIRVSDNGIGIAPDDVATAFLRHATSKILTTRDLFNVHSLGFRGEALASIAAVADVKLTTAMDSGIGTQIHVKGGEVEAQSTAAHRRGTDVEVNDLFFNTPARLKYMKSQQTELGKIVDIVSRLAMANPDIAFTVSHDGNMVVRTAGQGDLRQTLAGIYGLSVARSMVDFKAQDLDFRVSGLTSLPETTRASRNYLSLVVNGRYIKNFQLTKAVIAGYGSKLMVGRYPMGVINIEMDAALVDVNVHPTKAEVRLSKEDQLSHLLSEAIRTRLAKENLIPDALDNLPKRERYDLDQLELTLNKISPKTMPSVQPQQGQQLRENTTTNLADTAAEEPTPAPTSPDLEIGDLDDQPIFNEPQRLAAWDQRYQRLASNVVPTLMADEPEPDISHVESAERFPNLTYLAQVHGTYLLAESGDGLYILDQHAAQERVNYEYYRQAIGEVSNDQQHLLVPIVLDYSAADAISIRDHRDVLESVGLYLEDFGQNSFVVEHHPTWFKAGQEEDTIKEMVDWVLRDGRMTVAAFREKTAIMMSCKRAIKANHHLDDRQARALLQKLPECENPFNCPHGRPVLVHFSNTDLEKMFKRIQDSHESGEMQA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: DPO3E_ECOLI
Sequence: MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAFDIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRTLHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFATDEEIAAHEARLDLVQKKGGSCLWRA
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (PubMed:6340117).  Contacts both the beta sliding clamp (dnaN) and the polymerase subunit (dnaE), stabilizing their interaction (PubMed:26499492).
What are the official names of this protein?
DNA polymerase III subunit epsilon.
Protein: YHFQ_BACSU
Sequence: MKKTLIILTVLLLSVLTAACSSSSGNQNSKEHKVAVTHDLGKTNVPEHPKRVVVLELGFIDTLLDLGITPVGVADDNKAKQLINKDVLKKIDGYTSVGTRSQPSMEKIASLKPDLIIADTTRHKKVYDQLKKIAPTIALNNLNADYQDTIDASLTIAKAVGKEKEMEKKLTAHEEKLSETKQKISANSQSVLLIGNTNDTIMARDENFFTSRLLTQVGYRYAISTSGNSDSSNGGDSVNMKMTLEQLLKTDPDVIILMTGKTDDLDADGKRPIEKNVLWKKLKAVKNGHVYHVDRAVWSLRRSVDGANAILDELQKEMPAAKK
What are the official names of this protein?
Putative ABC transporter substrate-binding lipoprotein YhfQ.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 8 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane raft; Lipid-anchor. Note=Present in detergent- resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion.
Protein: DHPAA_AEDAE
Sequence: MANMDIDEFKEFGKAAIDFVADYLVNIRDRDVLPSVEPGYLHDLLPNEIPEKGDDWKTIMEEFKRFIVPGLTHWQSPHFHAFYPSQTSYSSIVGETLAAGLGVVGFSWICSPVCTELEVIMMNWIGQLLNLPRCFLNCDEGNGGGVIQGSASESIFIAVLVAREQAVRRLKNEHPELTEAEIRGRLVAYTSDQSNSAVEKSGILGAIKMRLLPADDDCVLRGRTLKKAVEEDKANGLFPVIMVATLGTTGTCAYDNLEEIGPYCNDNKLWLHVDAAYAGASFCLPEYAWIKKGLEMADSLNFNLHKWLFVNFDCCAMWFKDAAMITEAFSVDRIYLQHKFQGMSKAPDYRHWQIQLGRRFRSLKVWITLKTMGAEKIRELIRFHISLAQKFEQYVRADPRFEVTSSTLALVCFRLKGEDTYSKQLLDNIVKRKKIYMIPATYQGKFILRFMIAGIDPQAEDIDYAWNEVKSQTDLLLGVDDNGNNVCSKKLIKEEIFEKDNPVGKITESLGGLVLANEKAQ
What is the function of this protein?
Catalyzes the decarboxylation-oxidative deamination of L-3,4-dihydroxyphenylalanine (L-DOPA) to 3,4-dihydroxylphenylacetaldehyde (DHPAA) (PubMed:21283636).  Involved in cuticle development (PubMed:31234914).  Probably responsible for the protein cross-linking during the development of flexible cuticles (PubMed:21283636, PubMed:31234914).
What are the official names of this protein?
3,4-dihydroxyphenylacetaldehyde synthase, DHPAA synthase, DOPAL synthase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: RISB_METMA
Sequence: MTISLGFVVAEFNRDLTYQMELLGREHAEFLGATVKETILVPGVFDMPLAIKKLCQREDIDAVVTIGSVIEGETDHDQVVMQHAARKIMDLSLEFNKPVTLGIPGPGMTRMAAHERVDYAKRAVEAAVKLVRRL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RM27_BOVIN
Sequence: MALAVLAWRTRTAVIALLSPPQAAALAVRYASKKTGGSSKNLGGKSPGKRFGIRKMEGHYVHAGNILATQRHFRWHPGAHVGLGKNKCLYALEEGVVRYTKEVYVPSPSNSEAVDLVTRLPEGAVLYKTFVHVVPAKPEGTFKLVAML
What are the official names of this protein?
39S ribosomal protein L27, mitochondrial, L27mt, MRP-L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ARAA_YERPB
Sequence: MDVFKQSEVWFVIGSQNLYGPKTLQQVMDNAHQVVNSLNSEAGLPVKLVLKPLVTTPDEITALCREANYDTACIGIMTWLHTFSPAKMWIGGLSILNKPLLQFHTQFNAQIPWETMDMDFMNLNQTAHGGREFGFIGARMRQQHSVITGHWQDKEAHQRIGQWMRVAAAKQESQQLKVARFGDNMREVAVTEGDKVAAQIQFGYSVNAYGIGDLVAVVDAVSKGDIDTLVEEYEATYRFTDAVKLNGDKRENLLDAARIELGMTRFLEQGGFKAFTTNFENLYGLKQLPGLAVQRLMQQGYGFGGEGDWKTAALLRILKVMGTGLKGGTSFMEDYTYNFQPGNDLVVGSHMLEVCPSIAKEEKPLLDVQHLGIGGKADPARLIFSTPAGPALNASLIDMGNRFRLLVNVVDTVEQPHPLPKLPVARAIWQAQPSLATAAEAWIIAGGAHHTVFSQAVGVDELRLYAEMHGIEFLLIDNDTTLPAFKNEIRWNEVYYQLNR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: RECX_LEPCP
Sequence: MASNRPQLSLKGRALKYLAAREHSRAELARKLAPHAGDPAEIEAVLDDLQARGFLSEARYVASVVHRRAERFGVARIRQELLSKGTPADQMTDALDALRTTELERARELWRRRFGQPPADAREAARQNRFLMSRGFSSDVVRQVLRLADHEHDHDNT
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_STRP6
Sequence: MIDKRDDKPFKLKSKYKPSGDQPQAIESLVDNIEGGEKAQILLGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYADSAVSLRPGQEISRDTLLNQLVDIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRICEIESLTGKTIGEVDHLVLFPATHFVTNDEHMEQSIAKIQAELAEQLQLFESEGKLLEAQRLRQRTEYDIEMLREMGYTSGVENYSRHMDGRLPGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDQARKQMLVDYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGEYEMSQTNTIIEQIIRPTGLLDPEIDVRPSMGQMDDLLGEINQRVARDERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNVDGHVIMYADKMTDSMQRAIDETARRREIQIAYNKAHGIVPQTIKKDIRGLISISKTSHNDISKEEMDYESMSRGERKEAINALQKQMQEAAELLDFELAAQMRDLILELKLMD
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1388_MYCBO
Sequence: MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKAVAR
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator Mb1388c.
Protein: RK22_PHYPA
Sequence: MKSDKSNLEVRALAKHIRMSAHKARRVVNQIRGRSYEQALMILEFMPYRACYPILQLVSSAAANANHNLNLNRANLIISEAKVDEGPVLKRFQPRAQGRGYPIHKPTCHITITVKNKN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CDR_STAAN
Sequence: MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVIGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIDAINGNEITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
What is the function of this protein?
Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide.
What are the official names of this protein?
Coenzyme A disulfide reductase, CoA-disulfide reductase, CoADR.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
Protein: AIM4_KLULA
Sequence: MDKHSLQQQVSQLKRKNIENEDLSDVRKEDIKKPMSAELGIKSIFYDPDWNPSGKAPFGLKNIPYNPRTFRRDTPIEPRLNGLKEIPLPKPNIKDQDQKSS
What are the official names of this protein?
Altered inheritance of mitochondria protein 4.
What is the protein family that this protein belongs to?
Belongs to the AIM4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_SACD2
Sequence: MNLNYLDFEQPIADLEGKIEELQLVGSGNALNLSDELERLRQKSAKQTESIYSNLTPWQIVQVARHPQRPYSSDYISRMFEDWDELHGDRHFGDDKAIIGGVGRIDGKPVMVIGEEKGRSVKDKVYRNFGMPKPEGYRKALRLMEMAERFKMPVLTLIDTPGAYPGIDSEERGISESIAQNLAVMSRLRTPIICTVIGEGSSGGALAIGVGDQLNMLQYSTYFVISPEGCANIIWKTVEKAPLAAEAMGVTSSVLADLGIVDETIPEPLGGAHRDIDAMALKLKERLVSQLDRLQAVPIEELLDTRYQRLMSYGNSAV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_ACIBY
Sequence: MAKKGMINRELKREKTVAKYAAKRAELKATIANVNASDEERFEAMLKLQALPRNASPVRLRNRCGLTGRPHGYFRKFGLSRNKLRDTVMQGDVPGVVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: SYE_METJA
Sequence: MEEKILPIALRNAIKYNGKANPKAVLGIFLSENPEYRSKAKEVMPIVEKVVEEVNKLSLDEIKKKLEELGEDVKKKEKKEKGLELPNVKDKVVMRFAPNPSGPLHIGHARAAVLNDYFVKKYGGKLILRLEDTDPKRVLPEAYDMIKEDLDWLGVKVDEVVIQSDRIELYYEYGRKLIEMGHAYVCDCNPEEFRELRNKGVPCKCRDRAIEDNLELWEKMLNGELENVAVRLKTDIKHKNPSIRDFPIFRVEKTPHPRTGDKYCVYPLMNFSVPVDDHLLGMTHVLRGKDHIVNTEKQAYIYKYFGWEMPEFIHYGILKIEDIVLSTSSMYKGIKEGLYSGWDDVRLGTLRALRRRGIKPEAIYEIMKRIGIKQADVKFSWENLYAINKELIDKDARRFFFVWNPKKLIIEGAEKKVLKLRMHPDRPEFGERELIFDGEVYVVGDELEENKMYRLMELFNIVVEKVDDIALAKYHSDDFKIARKNKAKIIHWIPVKDSVKVKVLMPDGEIKEGFAEKDFAKVEVDDIIQFERFGFVRIDKKDNDGFVCCYAHR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_CORA7
Sequence: MKIHKGDMVIVISGPDKGAKGKVIEAYPKRDKVLVEGVNRVKKHVANSATERGAESGGIVTQEAPIHVSNVAIVDSEGNPTRVGYRFDENGKKVRIARSNGKDI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: ISCS_ECOLI
Sequence: MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH
What is the function of this protein?
Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis.  Catalyzes the removal of elemental sulfur from cysteine to produce alanine.  Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.  Preferentially binds to disordered IscU on which the Fe-S is assembled, IscU converts to the structured state and then dissociates from IscS to transfer the Fe-S to an acceptor protein.  Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate.  Transfers sulfur onto 'Cys-456' of ThiI and onto 'Cys-19' of TusA in transpersulfidation reactions.
What are the official names of this protein?
Cysteine desulfurase IscS, NifS protein homolog, ThiI transpersulfidase, TusA transpersulfidase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.