PharMolix/UniProtQA huggingface dataset:
Protein: SYT_SHIBS
Sequence: MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHAARETFANRGESYKVSILDENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM09_DROME
Sequence: MLKNIYVTPLNLLKSATSLQQQVRTTFVLKRKYDPPLHKTNEKPRRMRAKNFIYELVDDTLVKKRPNIEVVLKTFVEGVGDKGDVVSMKPHFVYNKLLLPGLAAYNTPENVAKYAKTEAEKSTVKHSSPYAQRTVNMLETIVLAVVMNKDEPWVLEPWHIKASLRKTGFYCREECITLPKERIEGPDLKKENKDFYCTVTINKLEQARLKCRLHHWSTDPSERLPYVLEHWKLQSEPLLDVCSPEKTP
What are the official names of this protein?
39S ribosomal protein L9, mitochondrial, L9mt, MRP-L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LACG_STAES
Sequence: MTKKLPDDFIFGGATAAYQAEGATQTDGKGRVAWDTYLEENYWYTAEPASDFYNRYPVDLELSERFGVNGIRISIAWSRIFPKGYGEVNQKGVEYYHNLFKECHKRHVEPFVTLHHFDTPEVLHKDGDFLNRKTIDYFVDYAEFCFKEFPEVKYWTTFNEIGPIGDGQYLVGKFPPGIKYDFEKVFQSHHNMMVAHARAVKLFKDENYKGEIGVVHALPTKYPYDPSNPEDVRAAELEDIIHNKFILDATYLGKYSRETMEGVQHILSVNGGQLEISDEDYKILDEAKDLNDFLGINYYMSDWMRGFEGESEITHNATGDKGGSKYQLKGVGQREFDVDVPRTDWDWMIYPQGLYDQIMRVVKDYPNYHKIYITENGLGYKDVFDEKEKTVHDDARIDYIKQHLSVIADAIADGANVKGYFLWSLMDVFSWSNGYEKRYGLFYVDFETQERFPKKSAYWYKELAESKEIK
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: RR18_VITVI
Sequence: MDKSKRPFLKSKRSFRRRLPPIQSGDRIDYRNMSLISRFISEQGKILSRRVNRLTLKQQRLITIAIKQARILSSLPFLNNEKQFERTESTARTTGLRTRNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: APJ1_YEAST
Sequence: MQQNTSLYDSLNVTAAASTSEIKKAYRNAALKYHPDKNNHTEESKRKFQEICQAYEILKDNRLRALYDQYGTTDEVLIQEQQAQAQRQQAGPFSSSSNFDTEAMSFPDLSPGDLFAQFFNSSATPSSNGSKSSFNFSFNNSSTPSFSFVNGSGVNNLYSSSAKYNSNDEDHHLDRGPDIKHNLKCTLKELYMGKTAKLGLNRTRICSVCDGHGGLKKCTCKTCKGQGIQTQTRRMGPLVQSWSQTCADCGGAGVFVKNKDICQQCQGLGFIKERKILQVTVQPGSCHNQLIVLTGEGDEVISTKGGGHEKVIPGDVVITILRLKDPNFQVINYSNLICKKCKIDFMTSLCGGVVYIEGHPSGKLIKLDIIPGEILKPGCFKTVEDMGMPKFINGVRSGFGHLYVKFDVTYPERLEPENAKKIQNILANDKYIKAERSTMETADSDCYCDLEKSYDSVEEHVLSSFEAPNLNNEVIEDDDLGDLINERDSRKRNNRRFDESNINNNNETKRNKYSSPVSGFYDHDINGY
What is the function of this protein?
Putative chaperone involved in protein folding.  Interferes with propagation of [PSI+] prion when overproduced.
What are the official names of this protein?
J domain-containing protein APJ1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PRS53_HUMAN
Sequence: MKWCWGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNTVPGEWPWQASVRRQGAHICSGSLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDLALLQLAHPTTHTPLCLPQPAHRFPFGASCWATGWDQDTSDAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGMLCGGPQPGVQGPCQGDSGGPVLCLEPDGHWVQAGIISFASSCAQEDAPVLLTNTAAHSSWLQARVQGAAFLAQSPETPEMSDEDSCVACGSLRTAGPQAGAPSPWPWEARLMHQGQLACGGALVSEEAVLTAAHCFIGRQAPEEWSVGLGTRPEEWGLKQLILHGAYTHPEGGYDMALLLLAQPVTLGASLRPLCLPYPDHHLPDGERGWVLGRARPGAGISSLQTVPVTLLGPRACSRLHAAPGGDGSPILPGMVCTSAVGELPSCEGLSGAPLVHEVRGTWFLAGLHSFGDACQGPARPAVFTALPAYEDWVSSLDWQVYFAEEPEPEAEPGSCLANISQPTSC
What is the function of this protein?
In vitro can degrade the fibrinogen alpha chain of as well as pro-urokinase-type plasminogen activator.
What are the official names of this protein?
Serine protease 53, Polyserine protease 3, Polyserase-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: ACPS_LISMH
Sequence: MIKGIGLDMIDLERVKQVVEKNPRFIERVLTEKEIKQFEKYEGNRKIEFLAGRFAAKEAYAKANGTGFGKHLSFTDVEILQVEDGRPHVTLPANAGENVFVSITHTARSAAAQVIIEI
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_CHLPD
Sequence: MHFSSYQDLRSSLLAGQTTCEEVTKSYLERIDRHCDDNIFLAVFHEQALSRARSLDRRFSEGGTPGLLFGMPMAIKDNISIKGARLTCASRILENYESVYDATVIERLLNEDAVFIGKTNMDEFAMGSSNENSAFGPVANPFDKTRVPGGSSGGSAAAVAAGLALVALGSDTGGSVRQPAGFCDIVGLKPTYGRISRYGLVAFASSFDQIGVLARNSDDAALVLGVMAGADERDATSSRHAVSNYAEEMAAVSPDGLKIGVPKEFFHESLNPDVARLVKAKLEELREKGAELVDITLPASDYAIAAYYILVTAEASSNLARFDGARYGYRSPNCDNLSAMYVNSRTEGFGKEVKRRIMLGTYVLSAGYYDTYYKKAQQVRRVFQDRYREALEKVDVIAGPTSPFPPFGIGDKMDDPLEMYLADVFTVPASIVGMPAISVPIGYDSLNLPVGMHLICNFFEEGKLLGIAGLMQHSIV
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS8_ACIC1
Sequence: MMTDPIADMLTRVRNANSAYHDTVVIPYSKIKANIAEILQREGYIAGYRVDPVPGHATAKNLVITLKYGPNRERSISGVRRVSKPGLRVYAKAENLPRVLGGLGIAIISTSAGLLTDRQCAKRRIGGEVLAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NU4LM_CHOCR
Sequence: MFQQLNCTNISSLLFLVSLLGIFLNQKNILVMLMSLEMMFLSISFNLIFSSIRLDDIIGQIFSLLILTVAAAESSIGLAILVIYYRIRSTITVELMNLMKG
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: SCGR3_HUMAN
Sequence: MGCCGCGSCGGCGGGCGGCGGGCGGGCGGGCGGVCGSCTTCRCYRVGCCSSCCPCCRGCCGGCCSTPVICCCRRTCRSCGCGCRKGCCQQKCCCQKQCCC
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Small cysteine and glycine repeat-containing protein 3, Keratin-associated protein 28-3.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 28 family.
Protein: YO079_YEAST
Sequence: MAMYFPISLLLLLLIRVSSEIPTFTGSLIVVLVFALFGLNSNTFPSSLSFSCLLISLFMLYTMSIILLPFLRFRGAYWVVLLTFTVLLTFLTFLIFLFDCLFFPLEVGLLSEANSACQFEERAIKTVRYLLY
What are the official names of this protein?
Putative uncharacterized membrane protein YOL079W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PUS5_KLULA
Sequence: MLRRGFIKQPPFVKIFKIVSPESTNAKATHCEVEFPLKVQELWRDKHHVIFNKPPLALSQLPDKRTWYNTHDYDPPVLLDIVQSSSGSILKDGTYEPSYYPIHRIDTPVSGGIVYAVNKQSAQQFSRNLRYGGNKGFSLTRKYVAKVGKSKTANECKEGLIKWNGAITYFQRVDNEHLILQLVTGKKHQIRKLTQQVLDSPIYNDLKYGGKKVFDSDFQIALHSAYIRTKIGFNIHEQIIPVPDGFRMIWGESVDQNGNFNEDITRVLKEDWAGTIKECLKKLKIQETKLADNQLIFVS
What is the function of this protein?
Pseudouridylate synthase responsible for the pseudouridine-2819 formation in mitochondrial 21S rRNA.  May modulate the efficiency or the fidelity of the mitochondrial translation machinery.
What are the official names of this protein?
21S rRNA pseudouridine(2819) synthase, Pseudouridine synthase 5, Pseudouridylate synthase PUS5, Uracil hydrolyase PUS5.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HUTU_YERP3
Sequence: MTTQNRFRDNEIRAPQGTQLTAKSWLTEAALRMLMNNLDPDVAENPKELVVYGGIGRAARNWECYDKIVESLINLNDDETLLIQSGKPVGIFKTHSNAPRVLIANSNLVPHWANWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHFGGSLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLKTRYVDEQATDLDDALARIEKYTATGVAVSIALCGNAAEILPELVRRGVRPDMVTDQTSAHDPLNGYLPKGWNWEEYRQRAQHEPALVINAAKISMAEHVEAMLAFHNMGIPTFDYGNNIRQMAHDMGVIRAFDFPGFVPAYIRPLFCRGIGPFRWVALSGNPDDIYKTDAKVKALIPDDAHLHHWLDMARERIRFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPVVIGRDHLDSGSVASPNRETEAMQDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVVVCDGSDEAAERIARVLHNDPATGVMRHADAGYDIAVNCAQEQGLNLPMVAATQGKKS
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LA_AEDAL
Sequence: MTEVEAKATATEETTKEEEEAPETTAEQTEESAQETSENVSKLEASTIRQLEYYFGDANLARDKFLQEQISKDEGWVPVDVLLTFKRLKSLSEDKKVIVDAIEKSDEGLIEVSEDREKLRRHPERPLPEQNEETRKEIYGRTVYVKGFAPEEGTQMSELLEFFEPFEKITNIVMRKYHDKATKKYLFKGSVFVTFATKDHCAEFLKKEKLGYKGKELIRKMQDDYFEEKKAERRKKDKKKEEDRFNIDHLPKGASVHLSGFNKDTSRETIKETILKLDESLEVAFIDYAKTDTEGTVRFAADDAGKKFMEKLTDSKIQIDEEEITARLLEGDEEKEFLRKVVKDQQARRQASNARNKGRTPEGRQASRPPQEWRRKAKGGRGE
What is the function of this protein?
May be involved in transcription termination by RNA polymerase III.  Binds RNA and DNA.  Binds to the 3' end of the minus strand of Sindbis virus RNA.  This may be significant for Sindbis virus RNA replication.
What are the official names of this protein?
La protein homolog, La autoantigen homolog, La ribonucleoprotein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Primarily nuclear, but significant amounts are present in the cytoplasm.
Protein: ATPG_KLEP7
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQERMAASRPYADTMRKVIGHLANGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKAWSDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYVVSNKFINTMSQVPTITQLLPLPASEDADLKRKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KLF17_PIG
Sequence: MEQGAEGLSQWPVAPHQFTEDTEKSLSFLDMSSSPGSGGVHTSWNRGPSGIRRVPQCPELERMSLASAQAPRQSACEMGQQFSMSPPEHGLSYCPQMTFTASQMVYSQGMSPSQPGMGAFKGAQAMPLGEPSISSVAVTFSGNLRMPPSGLPVSPPSGIPLMSHIGMPTMPYSGLPTVPFNGDALTPNMFLDPTMPPTEVQAVLPSLAQMLPSRDPQDFAMPPAGSPSLLPLESQGSFLSQPVSQEDFPKHHLCEPRREAQNSRAQERASGRSSPVSRPYHCEYENCGKAYTKRSHLVSHQRKHTGERPYKCTWEACTWSFFRSDELGRHTRIHTRYRPHKCDQCGRQFMRSDHLRQHQRTHMRMPRSPDPQADSGRRAGPLPAPHL
What is the function of this protein?
Transcription repressor that binds to the promoter of target genes and prevents their expression.  Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer.  Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression.  May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development (By similarity).
What are the official names of this protein?
Krueppel-like factor 17.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NS1_I63A1
Sequence: MDSNTITSFQVDCYLWHIRKLLSMRDMCDAPFDDRLRRDQKALKGRGSTLGLDLRVATMEGKKIVEDILKSETDENLKIAIASSPAPRYITDMSIEEISREWYMLMPRQKITGGLMVKMDQAIMDKRIILKANFSVLFDQLEALVSLRAFTDDGAMVAEISPIPSMPGHSTEDVKNAIGILIGGLEWNDNSIRASENIQRFAWGIRDENGGPPLPPKQKRYMARGIESEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: MTNW_BACC4
Sequence: MSGIIATYLIHDDSHNLEKKAEQIALGLTIGSWTHLPHLLQEQLKQHKGNVIHVEELAEHEHTNSYLRKKVKRGIIKIEYPLLNFSPDLPAILTTTFGKLSLDGEVKLIDLTFSDELKKHFPGPKFGIDGIRNLLQVHDRPLLMSIFKGMIGRNIGYLKTQLRDQAIGGVDIVKDDEILFENALTPLTKRIVSGKEVLQSVYETYGHKTLYAVNLTGRTFDLKENAKRAVQAGADILLFNVFAYGLDVLQSLAEDDEIPVPIMAHPAVSGAYSASKLYGVSSPLLLGKLLRYAGADFSLFPSPYGSVALEKEEALAISKYLTEDDAFFKKSFSVPSAGIHPGFVPFIVRDFGKDVVINAGGGIHGHPNGAQGGGKAFRTAIDATLQNKPLHEVDDINLHSALQIWGNPSYEVKL
What is the function of this protein?
Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
What are the official names of this protein?
2,3-diketo-5-methylthiopentyl-1-phosphate enolase, DK-MTP-1-P enolase, RuBisCO-like protein, RLP.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: DPO2_ECOLI
Sequence: MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETTRHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
What is the function of this protein?
Thought to be involved in DNA repair and/or mutagenesis.  Its processivity is enhanced by the beta sliding clamp (dnaN) and clamp loader (PubMed:1999435, PubMed:1534562).
What are the official names of this protein?
DNA polymerase II, Pol II.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: CLPX_LEPIN
Sequence: MAKKTPGNNGKQKLFCSFCGKEQDAVKRLVAGPGVYICDECISLCNEIIAEDHEHSHEKSEVFSEVPSPADIKSILDQYVIGQDHAKKALSVAVYNHYKRVNLKEKKSDVEIEKSNILLIGPTGSGKTLLAQTLARIIKVPFAIVDATALTEAGYVGEDVENIILKLIQNADNDIKKAEVGIIYIDEVDKIARKSDSASITRDVSGEGVQQALLKIIEGTVANVPPQGGRKHPHQEYLQVDTKNILFILGGAFVDLPNIIKSRTGIKTIGFGSEEQRIQSENKDVLMEQVIPEDLIKFGLIPEFIGRLPIVATLQELNVDMLRQIFREPKNSVLKQYTRLLELENVKLTFHDEAIDKIAELAIKRESGARGLRAIVENIMLDLMFDIPSRKDIEEVIITAEVIANRVAPTLILKKESKIA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: AMPA_SYNC1
Sequence: MQIVVGCMPALTLKTDCLMLGVWQDRTDTPLLKELDTALHGALGQSVDSKAFVGKEGETLLFQTGAGLPAARVLLIGLGAYAQADCGAMRRGAAEGARVLQQQRVKRAGLALSEAPAGLPLTQAVQVLVEGLLLASYRFDRFLTQKREDLPPLLETLDILIADQGSLEGVAAAVERARHIGHGVALARDLVNQPGNVKSPEFLAERARQLAGECGLSCTVLEQEQLEREGFGALLAVAQGSARPPRLIVLEYRGGAPDEKPLALVGKGVVFDSGGISLKPGEKMDEMKMDMAGAAAVFGAMSAAAGLRLPVNLVAIVPAVENLPSASAYRPGDIITSLSGRTIEVLNTDAEGRLILADALTYAGRFEPRAVIDLATLTGACIIALGHEASAVFSNRDELARNLIRAGETSRERLWQLPLWDSYDKQIKSEIADMKNTGGRPAGTITAAAFLQRFVPDCPWAHIDIAGTAWEAKGTALCPRGGTGVGVRLLIDLLEQE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_PECAS
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEEIATGHDHLALVYGDISGSVPVLARVHSECLTGDALFSLRCDCGFQLEAALGHIAEEGRGVLLYHRQEGRNIGLLNKIRAYALQDLGADTVEANHQLGFAADERDFTLCADMFKLLDVDEVRLLTNNPQKVKILNEAGINIVERVPLIVGRNPKNEHYLATKAAKMGHILDMK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: PYRE_ACTP7
Sequence: MEQYKHDFIEFALSRNVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLAKLGEFYAQAIQASGLNFDVLFGPAYKGIPIATTVAVALVNQFDVDKPCCFNRKEAKDHGEGGNLIGSPLKGRILLVDDVITAGTAIRESMEIINANQAELAGVLIALNRKEKGKGELSAIQEVERDYGCQVFSIIDFDDLIQFIEKSEQYAPYLASMRAYREQYGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RS8_THEM4
Sequence: MWSDPIADMLTRIRNANVVFKDQVDIPASNLKKEIAEILKREGFIKDYTYIEDGKQGIIRIQMKYKGTRRNRERVIHGIVRISKPGRRIYVDKEHLPKVKNGLGIAILTTSKGVITDKQAREIGVGGEVIAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TIG_HELPH
Sequence: MNLEVKKIDTANARLSAKLSIENLEKRYDKIAQKIAQKVKIDGFRRGKVPLSLVKTRYQAQIEQDAQEEMIQEVLKNAFKELGIENKDLIGSPNLTKFEKKDTHFEIEADIGLKPTIVLDKIKECVPSVGVEIPNEEKINERLKQLAKDYAKFVDTDAQRKAQNDDKLTIDFEGFIDNAPFEGGKAENFNLILGSKQMLEDFEKALLGMQAGEEKEFPLTFPSGYHAEHLAGKEALFKVKLHQIQAREALEINDELAKIVLANEENATLKLLKERVEGQLFLENKARLYNEELKEKLIENLDEKIVFDLPKTIIEQEMDLLFRNALYSMQAEEVKSLQESQEKAKEKRESFRNDATKSVKITFIIDALAKEEKIGVHDNEVFQTLYYEAMMTGQNPENLIEQYRKNNMLAAVKMAMIEDRVLAYLLDKNLPKEQQEILEKMRPNAQKIQAG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: GATA_TRIL1
Sequence: MELYEQTIHNLQTQLQARQVSSVEITNSFLDRIESTDQSINAFITVTKEQALLDAAAADQRIAAGNCAPLTGIPVALKDIFLTEGVRTTSASKMLDNFIAPYDATAWTRMKSQGAVLLGKLNQDEFAMGSSCENSAFGPTRNPWNKDHIPGGSSGGSAAAIAAQQAVATLGTDTGGSIRQPASHCGCVGLKPTYGRVSRYGVIAYASSLDQVGPMTRDVTDAALLLGVIAGYDPKDSTSVDCPVPDYTAALQQGVKGLTIGLPKEYFIDGLDADVQQAMEQAIAVYRQLGAEFVEVSLPHTNYAVATYYLIATAEASSNLARYEGVRFGHRAKDTAGLIDLMMQSRSEGFGAEVKRRIMLGTYALSSGYYDAYYIKAQKVRTLIQQDFNEAFRSVDLLLTPVAPTPAFRIGEKTADPLQMYLSDIFTIPVNLAGICGISVPAGISSNGLPIGLQLLGRPFGEETILRAAFDFEQATQWHTKKAAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SYM_CERS4
Sequence: MARILITSAIPYINGIKHLGNLVGSQLPADLYARYMRGRGHEVMFICATDEHGTPAELAAAKAGKPVEDYCAEMHEVQKEIAAGFRLSFDHFGRSSSARNHRLTQHFAGALAENGFIEEVVERQFFSVADNRFLPDRYIEGTCPNCGYDKARGDQCENCTKQLDPTDLIDPRSAISGSTELELRETKHLYLRQRALKDEIEAWIDSKTDWPVLTTSIAKKWLHDGEGLQDRGITRDLKWGVPVRKGSEPWPGMEGKVFYVWFDAPIEYIAGTAEWADANGKADADWERWWRTDRGAEDVRYVQFMGKDNVPFHTLSFPATIMGSREPWKLVDYIKSFNYLNYDGGQFSTSQGRGVFMDQALSILPADYWRWWLLSHAPENSDSEFTWENFQSSVNKDLADVLGNLVSRVTKFCRSKFGETVPAGGSPGEREHQLVAELQQRLAAYEACMEAMEVRKAASELRALWVAGNEYLQSAAPWTVVKTDPEQAQAMIRLALNLIRLYAVISRPFIPDAAASMMASLGCEDWSWPADVGRALEVLPAGHGFTTPEVLFRKITDEERAEWQTRFSGVRS
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.