PharMolix/UniProtQA huggingface dataset:
Protein: YBIR_ECOLI
Sequence: MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHTIITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVALFIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFIAQMAPLAGAMMLTLLLLCWCCFPGKAMQYHTGVQTPEWKPRLVWSCLGLYIVFLTALEFKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVSHLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLVWAVNVGGFGLLPGSLANLIALRMANDRRIWWRFHLYSIPMLLWAALVGYVLLVILPAN
What are the official names of this protein?
Inner membrane protein YbiR.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G6PI2_STRCO
Sequence: MNADGRTRLHQTPEWAALVKHREQLGEVRLREMFAADPGRGTGWTLRVGDLHVDYSKHLVTDETLALLQELAAATGVSGLRDAMFRGERINITEDRAVLHTALRAPRDAVIEVDGENVVPQVHAVLDKMAGFADRVRTGEWTGHTGRRIRNVVNIGIGGSDLGPAMAYEALRAFTDRSLTLRFVSNVDGADLHEAVRDLDPAETLFIIASKTFTTIETITNATSARSWLLAGLGGDEKAVAKHFVALSTNAEKVADFGIDTANMFEFWDWVGGRYSFDSAIGLSLMIAIGPDRFREMLDGFHLVDEHFRTAPAESNVPLLMGLLGVWYGSFLGAQSHAVLPYSHYLSKFTAYLQQLDMESNGKSVDREGKPVQWQTGPVVWGTPGTNGQHAYYQLIHQGTKLIPADFIGFARPVDELSEELKSQHDLLMANFFAQTQALAFGKTPDEVRAEGVPEELVPHKTFPGDHPTTTILARELTPSVLGQLVALYEHKVFVQGAIWNIDSFDQWGVELGKVLAKRVEPALTEGADVPGLDPSTGALVAAYRELRGRR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 2, GPI 2, Phosphoglucose isomerase 2, PGI 2, Phosphohexose isomerase 2, PHI 2.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASQ1_MOUSE
Sequence: MRATDRMGARAVSELRLALLFVLVLGTPRLGVQGEDGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEEDSVYVFKGDEVIEYDGEFSADTLVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAYEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPMTIPDKPNSEEEIVSFVEEHRRSTLRKLKPESMYETWEDDLDGIHIVAFAEEADPDGYEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSIWMEMDNEEDLPSADELEDWLEDVLEGEINTEDDDDDDDDDDDDDDDDD
What is the function of this protein?
Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.  Calcium ions are bound by clusters of acidic residues at the protein surface, often at the interface between subunits.  Can bind around 80 Ca(2+) ions (By similarity).  Regulates the release of lumenal Ca(2+) via the calcium release channel RYR1; this plays an important role in triggering muscle contraction.  Negatively regulates store-operated Ca(2+) entry (SOCE) activity (By similarity).
What are the official names of this protein?
Calsequestrin-1, Calmitine, Calsequestrin, skeletal muscle isoform.
What is the protein family that this protein belongs to?
Belongs to the calsequestrin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Sarcoplasmic reticulum. Sarcoplasmic reticulum lumen. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Mitochondrion matrix. Note=This isoform of calsequestrin occurs in the sarcoplasmic reticulum's terminal cisternae luminal spaces of fast skeletal muscle cells (PubMed:22049211). Preferentially forms linear and round aggregates in the endoplasmic reticulum (ER) of resting cells. In a minority of cells, homogeneously detected in the ER lumen. Colocalizes with STIM1 at endoplasmic reticulum in response to a depletion of intracellular calcium (By similarity).
Protein: SMC4_YEAST
Sequence: MSDSPLSKRQKRKSAQEPELSLDQGDAEEDSQVENRVNLSENTPEPDLPALEASYSKSYTPRKLVLSSGENRYAFSQPTNSTTTSLHVPNLQPPKTSSRGRDHKSYSQSPPRSPGRSPTRRLELLQLSPVKNSRVELQKIYDRHQSSSKQQSRLFINELVLENFKSYAGKQVVGPFHTSFSAVVGPNGSGKSNVIDSMLFVFGFRANKMRQDRLSDLIHKSEAFPSLQSCSVAVHFQYVIDESSGTSRIDEEKPGLIITRKAFKNNSSKYYINEKESSYTEVTKLLKNEGIDLDHKRFLILQGEVENIAQMKPKAEKESDDGLLEYLEDIIGTANYKPLIEERMGQIENLNEVCLEKENRFEIVDREKNSLESGKETALEFLEKEKQLTLLRSKLFQFKLLQSNSKLASTLEKISSSNKDLEDEKMKFQESLKKVDEIKAQRKEIKDRISSCSSKEKTLVLERRELEGTRVSLEERTKNLVSKMEKAEKTLKSTKHSISEAENMLEELRGQQTEHETEIKDLTQLLEKERSILDDIKLSLKDKTKNISAEIIRHEKELEPWDLQLQEKESQIQLAESELSLLEETQAKLKKNVETLEEKILAKKTHKQELQDLILDLKKKLNSLKDERSQGEKNFTSAHLKLKEMQKVLNAHRQRAMEARSSLSKAQNKSKVLTALSRLQKSGRINGFHGRLGDLGVIDDSFDVAISTACPRLDDVVVDTVECAQHCIDYLRKNKLGYARFILLDRLRQFNLQPISTPENVPRLFDLVKPKNPKFSNAFYSVLRDTLVAQNLKQANNVAYGKKRFRVVTVDGKLIDISGTMSGGGNHVAKGLMKLGTNQSDKVDDYTPEEVDKIERELSERENNFRVASDTVHEMEEELKKLRDHEPDLESQISKAEMEADSLASELTLAEQQVKEAEMAYVKAVSDKAQLNVVMKNLERLRGEYNDLQSETKTKKEKIKGLQDEIMKIGGIKLQMQNSKVESVCQKLDILVAKLKKVKSASKKSGGDVVKFQKLLQNSERDVELSSDELKVIEEQLKHTKLALAENDTNMNETLNLKVELKEQSEQLKEQMEDMEESINEFKSIEIEMKNKLEKLNSLLTYIKSEITQQEKGLNELSIRDVTHTLGMLDDNKMDSVKEDVKNNQELDQEYRSCETQDESEIKDAETSCDNYHPMNIDETSDEVSRGIPRLSEDELRELDVELIESKINELSYYVEETNVDIGVLEEYARRLAEFKRRKLDLNNAVQKRDEVKEQLGILKKKRFDEFMAGFNIISMTLKEMYQMITMGGNAELELVDSLDPFSEGVTFSVMPPKKSWRNITNLSGGEKTLSSLALVFALHKYKPTPLYVMDEIDAALDFRNVSIVANYIKERTKNAQFIVISLRNNMFELAQQLVGVYKRDNRTKSTTIKNIDILNRT
What is the function of this protein?
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
What are the official names of this protein?
Structural maintenance of chromosomes protein 4.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC4 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein: PARE_STAAC
Sequence: MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEIVDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMPTGIHKSGKPTVEVIFTVLHAGGKFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGKTKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEHYHYEEGIKEFVSYVNEGKEVLHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVRTKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREGLTAVVSVRIPEELLQFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKAREDARSGKKNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAILPLRGKVINTEKARLEDIFKNEEINTIIHTIGAGVGTDFKIEDSNYNRVIIMTDADTDGAHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTDEELNKLQKELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQPRREWIEKHVEFGMQEDQSILDNSEVQVLENDQFDEEEI
What is the function of this protein?
Topoisomerase IV is essential for chromosome segregation.  It relaxes supercoiled DNA.  Performs the decatenation events required during the replication of a circular DNA molecule.
What are the official names of this protein?
DNA topoisomerase 4 subunit B, Topoisomerase IV subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family. ParE type 2 subfamily.
Protein: PSBL_TYPAN
Sequence: MTQSNPNEQSVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GH_EHV2
Sequence: MMRYSLLCTCLFLAWWAIGGRGLATPYPSTPEFSGSPGSRATSGSPGTPKSLSATPRKILPTAKSVNYTEMIEKNPSLTIDLGNQTKYQLNWTDVVKVIPGELIEKMWEESNVTESLWFTLNKFTDVYKKDTIFKNFTGHFTTKYVCNVSQGEPNYNVSQREVKEIKEYDGKFGIPAPVVLSDLLASVNYVLRPQHATHNVFYTTRDYDAYFSVFFGDKDTQMLGYITRDFSFVTAVSWTNGTFRFLTTMMGYTDRLPVLKGHLIYKTDFIVGQNERFSMVILTTFLDHAYFESLVHPDFQGIFKDLTERPPAEVIVELQDKMVELEATQKCPVQSMSKITFEYVLKFAFSHFMAVAGLEDAGQHVKVRCLFDVLHELALLRAMTATCFHPFYFKGFTSNHLSSVATVMVTRTPIKQLKTFSHGDRDAVLATLQVADNVKEATDRILWAAAEIMDDIYTAYTDSFYLKLEDRGHLLDVFVLLRDKEKQHQVLKNRNLMIIYLTAGSMCNSVEISTVTSMLSDKNHYSLRRTFSPCLMSLRFDFTKDKLISETRLLPNMTYLRAEDGATGFFNILRDRHVATFNLLPVSSCLKAYAKNILMVIPMFNLTYVVSTAPISIGINYDVRDTFIEKKMFVSAVMSNCSTFPEGSGTRQIPIVYNITRSRSECPLCGAAFLAYDERDGLESMMYVTNRRVERNIFSDASPFFDNQNLHTHYLMLFKNGTVIEIRGRYRERTAQFIIITLFILTLMFGAFLAFKIFVYCC
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL.  May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis.
What are the official names of this protein?
Envelope glycoprotein H, gH.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein H family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: CCC11_ARATH
Sequence: MAANFWNSSHYKQLLDPEEVDVVHDLDKERGISIDDFKLIKFHMSNHIMKLAQHIKVRQRVVATAITYMRRVYIRKSMVEFEPRLVALTCLYLASKAEESIVQARNLVFYIKRLYPDEYNKYELKDILGMEMKVLEALDYYLVVFHPYRSLSEFLQDAALNDVNMNQITWGIVNDTYKMDLILVHPPYRIALACIYIASVHREKDITAWFEDLHEDMNLVKNIAMEILDFYENYRTITEEKVNSAFSKLALKL
What are the official names of this protein?
Cyclin-C1-1, CycC1;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
Protein: EIF3F_PHANO
Sequence: MSERDSFLHLARPLGPAPVGAQPSTAPLNVAIQPQAVFSILDHSLRRPADQERVIGTLLGTRSEDGTEIEIRNCYAVPHTETAEQVEVDMDYQKQMLALHLRANPREVLVGWYATSSDLNTFSALIQNFYSQQGDGTWPHPAVHLTVSTVPGQDIESRTYISAPIGVTAERAADSCLFIPVPHEIKYGEAEKSGLELISSAKDREDRSQEIMTDLDSLERAVQHVLDMLERVSNYVNNVLDEEAEPSSALGQFLMNALSLAPKVDPADIERDFNNHIQDVLVVSYLANTIRTQIDLSNRLATAALTMGGTDALAGDGQKDGGDRKQGGDRRNKGRQQRTQEA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit F, eIF3f.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit F family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TFG_HUMAN
Sequence: MNGQLDLSGKLIIKAQLGEDIRRIPIHNEDITYDELVLMMQRVFRGKLLSNDEVTIKYKDEDGDLITIFDSSDLSFAIQCSRILKLTLFVNGQPRPLESSQVKYLRRELIELRNKVNRLLDSLEPPGEPGPSTNIPENDTVDGREEKSASDSSGKQSTQVMAASMSAFDPLKNQDEINKNVMSAFGLTDDQVSGPPSAPAEDRSGTPDSIASSSSAAHPPGVQPQQPPYTGAQTQAGQIEGQMYQQYQQQAGYGAQQPQAPPQQPQQYGIQYSASYSQQTGPQQPQQFQGYGQQPTSQAPAPAFSGQPQQLPAQPPQQYQASNYPAQTYTAQTSQPTNYTVAPASQPGMAPSQPGAYQPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGYR
What is the function of this protein?
Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252).  Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus (PubMed:21478858).
What are the official names of this protein?
Protein TFG, TRK-fused gene protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=Localizes to endoplasmic reticulum exit site (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:27813252, PubMed:21478858).
Protein: RAD50_PYRHO
Sequence: MKIERVIVQNFRSHKNSEIEFKPGINLIIGQNGAGKSSLLDAILVGLYWSKRMRLRGLKKDEFTRTGTRGAIIEITFEEDGTKYKVLRDFARNVSYLKRLDGREWRHVTETSMESVSSFIDRIIPYNVFLNAIYVRQGQIDAILESDETRDKIVKEILNLDKLEKAYDNLGKIRKYIKYSIEEKEKFIMKTENIEDLIRTQEKSFTEVLNEIRNISSNLPRLRRELEGIKEEVKTLEATFNSITELKLRLGELNGKKGRLEERIRQLESGIEEKRKKSKELEEVVKELPELEKKETEYRRLIEFKDEYLVKKNELEKRLGILSNRLQEVKRKIKDAESKVARIRWIEERLKEIQEKIMKLEPRVREFEDAMRLKAQMESLKSKLGGLEPEKINEKLLYLENRKKELEEEIDKITRKIGELNQRSKDRRLAIIELKKARGKCPVCGRELTEEHKADLLRKYSLELSSIEKEIQEAKALERQLRAEFRKVENELSRLSSLKTIADQIIEIRERLSKINLEDLKRDKEEYELLKSESNKLKGEVESLKKEVNELNDYKNESTKLEIEIDKAKKELSEIEDRLLRLGFKTIDELSGRIRELEKFHNKYIEAKNAEKELRDILESLKDEREELDKAFEELAKIETDIEKVTSQLNELQRKFDQKKYEEKREKMMKLSMEIKGLETKLEELERRRDEIKSTIEKLKEERKERESAKMELEKLNIAIKRIEELRGKIKEYKALIKEEALNKIGEIASEIFSEFTDGKYSGIAIRAEDNKVKLFVIYDGVERPLTFLSGGERIALGLAFRLAMSMYLIGKVDLLILDEPTPFLDEERRRKLIEIMERHLRKISQVIIVSHDEELKDAADHVIRIRLEGGASKVEVVS
What is the function of this protein?
Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair.  The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA.  Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex.
What are the official names of this protein?
DNA double-strand break repair Rad50 ATPase.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
Protein: VLYS_BPOX2
Sequence: MAAPRISFSPSDILFGVLDRLFKDNATGKVLASRVAVVI
What are the official names of this protein?
Lysis protein.
Protein: GHRL_CARAU
Sequence: MPLRRRASHMFVLLCALSLCVESVKGGTSFLSPAQKPQGRRPPRMGRRDVAEPEIPVIKEDDQFMMSAPFELSVSLSEAEYEKYGPVLQKVLVNLLGDSPLEF
What is the function of this protein?
Ligand for growth hormone secretagogue receptor type 1 (GHSR).  Induces the release of growth hormone from the pituitary.  Induces adiposity and stimulates gastric acid secretion.  Involved in growth regulation (By similarity).  Has an appetite-stimulating effect.
What are the official names of this protein?
Ghrelin.
What is the protein family that this protein belongs to?
Belongs to the motilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PI_LEGPN
Sequence: MIRNSMKSHTELLSWNLLQKEADRVRLNSDSLTCVVPDSNNYESSKQINCIEYDYSRQRVNRTIIDLLIDLANEVKLQEKIDNLINGKKINISENRPALHTALRDLGNKSIMIDGLDIMSAVINTREKIKVISNQIREKKWLGHSGLPITDIVNIGIGGSDLGPRVCINALSNYISKEFNYHFISDVDPASFNDVIAKINPQTTLFIVSSKSFTTKETLLNARKAFALYEDTASIDQHFIAVTAHPERAYQMGIKTVLPIWDWVGGRFSFCSAVNLITAIAIGYEQFVELLAGAHDIDTHVQFTDFKNNIPVLMALIGIWNNNFLNIHYDLIGYNFKEYFVPYVQQLDMESNGKSIDVNGRMVDYATGPIVWGGLGNQAQHSYFQLLCQGTHRCVGDFITLKTNDEHEINSMCHYKMKVLSEGIQTIENPYGYIPGNMPMNHLILSDCSPYTLGALVALYEHKIFEQSVIWNINPFDQPGIESAKSAHREITLSSES
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAAT1_DROER
Sequence: MELKGVQPSNGSANGNGTTNAASTEKTDAEKHTPERTNWGNGLEFLMSCISVSVGLGNVWRFPFTAYENGGGAFLIPYIIVLFLIGKPMYYLEMIMGQFTSQGTVKIWSVVPGFVGVGYGQAFGTICIISYYSSLLALTLYYLFVSFQSELPWSYCRDEWTNCVNSRPQEYVDNLLSGVSLANESARNFSAIGSVANEETEKLQSSSELYFLNVVIKEKLDISDGVGDPDWKLTLALLAAWVVIFLVIMRGVKSSGKAAYFLALFPYVVLFVLLIRAVTLEGARDGILFFLEPQWGELLNPTVWKEAVVQCFFSLAVGSGPIIMFASYNRFDHGIYRDAMIVTTLDTLTSLLGGITIFAILGNLAHNLQIENIRDVVRSGTGLAFISYPDAISKFKAVPQLFSVLFFFMLFVLGIGSIVALQSTIVTIICDQFKGLKYWKVALITSACGFLMGLVYVTPGGQWILTLVDFYGGTYVVFILAIFELAGIVWVYGLQNFCDDIEFMCNRRVSLYWRMCWSFFTPVMMIIIFIYSMVTIEPIKYSELYFPEAANIAGWLLFAIGAAQFPLWGLWYVSRHPQGTYWKSLKASMKPSERWGPANPETRREWVIFKNHKAAQRATQKDVSKLGFFWRKLTNFCGSNK
What is the function of this protein?
Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids.  Neutral amino acids are the preferred substrates, especially methionine and phenylalanine (By similarity).
What are the official names of this protein?
Sodium-dependent nutrient amino acid transporter 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYP_OCEIH
Sequence: MGKKNKQFVEKITAMEDDFAQWYTDVVKQADLVDYGQVRGTMIIKPYGYAIWENIKNELDRMFKETGHTNVAFPLFIPESLLQKEKDHVEGFAPEVAWVTHGGEEELTERIAVRPTSEVLFCDYYSNNIHSYRDLPKLYNQWGNVVRWEKTTRPFLRSSEFHWQEGHTAHATDEEATEETNRMLETYAKLVEEYLAVPVLKGRKTDKEKFAGAKFTLTIEALMHDGKALQSGTSHHFGTGFAEAFDINYLDKDGKSQFVHQTSWGLSTRIMGALIMVHGDNRGLVVPPKIAPTQAMIVPIAQHKEGVLDKAYELRDKLAKVARVDIDGSDKMPGWKFNEYEMKGIPVRVEMGPKDIEKEQVVLVRRDTGEKEFVPVAEVETRLVELLDEVQSNLYQRALDHRNEMTTVAKDMDEFKEKIEEGGFIKAMWCGDVSCEESIKEETTATSRCIPYEEEKVADTCVCCGKKAKELVYWARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJEN3_DANRE
Sequence: MNHSSNEKEPETIEPLRYLSKTEVATVETELLRDYRFGQQQLIEIWGHACAIAITKAFPLSSLSKKQPTLLVVCGPEQNGSIGLVCARHLRMFEYEPTIFYPKRSTLGLHQDFTVQCEKMDIPFLSYLPTEVQLLNDAYNLVIDAILGPETDHKDVKEPYAGMLVTLKQVKIPIVSVDVPSGWDADEPAKDGINPEVLISLTAPKKCATGFSGKHFLAGRFLPYDIQKKYELNLPEFPGTECIIEL
What is the function of this protein?
Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis (PubMed:23719382).  Orchestrates hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential.  YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence (PubMed:30705153).
What are the official names of this protein?
YjeF N-terminal domain-containing 3, ApoA-I-binding protein 2.
Protein: TMM69_HUMAN
Sequence: MLRFIQKFSQASSKILKYSFPVGLRTSRTDILSLKMSLQQNFSPCPRPWLSSSFPAYMSKTQCYHTSPCSFKKQQKQALLARPSSTITYLTDSPKPALCVTLAGLIPFVAPPLVMLMTKTYIPILAFTQMAYGASFLSFLGGIRWGFALPEGSPAKPDYLNLASSAAPLFFSWFAFLISERLSEAIVTVIMGMGVAFHLELFLLPHYPNWFKALRIVVTLLATFSFIITLVVKSSFPEKGHKRPGQV
What are the official names of this protein?
Transmembrane protein 69.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GLGE_MYCS2
Sequence: MRSGWVAGRIGIDDVAPVVSCGRYPAKAVVGEVVPVRATVWREGHDAVSATLVVRYLGTEFPRLASGPGTTPPAVPLGTVVQPGKRVKPQILQMSKGRTPDVFHGEFTPDAVGLWTFRVDGWGDPIATWRHAVEAKLEAGQSETELNNDLLVGARLLMRAAEGVPRKLRDPLLEAAQQLRTPGDPYQRAGGALSPEVADLLLQYPLREFVTRGEVHGVWVDRPLARFSSWYEMFPRSTGGWDENGHPVHGTFATAAAALPRIARMGFNVVYLPPIHPIGKVHRKGRNNSVTAAPGDVGSPWAIGSDEGGHDAVHPDLGTIDDFDAFVAAARDAGLEVALDLALQCAPDHPWAKEHPEWFTVLPDGTIAYAENPPKKYQDIYPLNFDNDPDGLFHEVLRVVKFWISHGVKVFRVDNPHTKPPNFWAWLIAEVKNEDPDILFLSEAFTRPARLYGLAKLGFTQSYTYFTWRTAKWELTEFGEEIAKYADHARPNLWVNTPDILHESLQHGGPGMFAIRAVLASTMSSSWGVYSGYELFEHRSVREGSEEYLDSEKYELRPRDFDGALARGESLEPFLTRLNEIRRLHPALRQLRTIKFHHLDNDALLAYSKFDPVTGDTVLVVVTLNPFGPEESTLWLDMEALGMEPYDRFWVRDEITGEEYQWGQSNYVRIEPAKAVAHVLNMPLIPYEKRLDLLRRE
What is the function of this protein?
Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans.  Is also able to catalyze the reverse reaction in vitro.  Cannot use glucose 1-phosphate as substrate.  Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.
What are the official names of this protein?
Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, GMPMT, (1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.
Protein: 4EB3L_DANRE
Sequence: MSTNTQQSKSCPIPTRVLHLKDWSQLPDCYSQTPGGTLFSTTPGGTRIIYDRKFLLDCRNSPIARTPPCCLPQIPGVTIPSLHPVSKLQELKEELEEEKELAADDSQFEMDI
What is the function of this protein?
Regulates eif4e1a activity by preventing its assembly into the eIF4F complex.
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-binding protein 3-like, 4E-BP3, eIF4E-binding protein 3, Eukaryotic translation initiation factor 4E-1A-binding protein, 4E-BP, eIF4E-1A-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eIF4E-binding protein family.
Protein: SELO_BACAH
Sequence: MTKNNEVGWNLDNSYATLPQSFYTEIPPTPVSSPELVKLNHSLAISLGFNPEELKKEAEIAIFAGNALPEGAHPLAQAYAGHQFGHFNMLGDGRALLIGEQITPSGKRFDIQLKGSGPTPYSRRGDGRAALGPMLREYIISEAMYALDIPTTRSLAVVTTGEPTYRETKLPGAILTRVASSHIRVGTFQYAAARGSIEDLQSLADYTIKRHYPEIEAHENRYTALLQEVIKKQASLIAKWQLVGFIHGVMNTDNITISGETIDYGPCAFMDNYDQGTVFSSIDTQGRYAYGNQPYMAAWDLARLAESLIPILHEDEEEALKIAQDEISKFSVQYEKQWFIGMKKKLGLFSNEEQDQSLIEQLFKMMEKYKADYTNTFRSLTLDTLENTPLFDSPEFKEWYKLWQSRLEKQEESKENAYEMMKNNNPSIIPRNHRVEEALEAAVTNGDYSVMEKLLEALANPYAYSTDQEEYCVPPAPTNRPYRTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: SSUH2_MOUSE
Sequence: MDRDPSEEDSMADLSFEAESPVLPPDELLEGLPSYDWLLQGRERQVFFPPLEALGRSQEPACWSSVLEHSRVPVVTEEVAREALLSFVNSHCCYSSAAAGNLIIQELRQQTLCRYRLETFSESRVSEWTFQPVTNHSVDGPQRGTSPRLWDMKVQVPPMFQEDTRKLQVPHSSLVKECHKCHGRGRYKCSGCHGAGMVRCSSCSGTKRKAKQPRRCHLCSGSGRRRCSTCSGRGNKTCATCKGERKLEHFVQLVIMWKNSLFEFMSPHHLHCPKELLAKARGENLFRDENATVYPIVDFPLQDISLASQRGIEEHSTMLASRARILQQMFFYSGGPFHHS
What is the function of this protein?
Plays a role in odontogenesis.
What are the official names of this protein?
Protein SSUH2 homolog, Protein ssu-2 homolog.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: Y823_HELPJ
Sequence: MRFLNNKHREKGLKAEEEACGFLKTLGFEMIERNFFSQFGEIDIIALKKGVLHFIEVKSGENFDPIYAITPSKLKKMIKTIRCYLSQKDPNSDFCIDALIVKNGKFELLENITF
What are the official names of this protein?
UPF0102 protein jhp_0762.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.