PharMolix/UniProtQA huggingface dataset:
Protein: PURL_CAMJR
Sequence: MDKETIKAHKISDEEYTQILEILGREPNLLELGVISAMWSEHCSYKSSKKYLNGFPTKAPWVIQGPGENAGVIDIGQGMAAVFKVESHNHPSFIEPFAGAATGVGGILRDVFTMGARVVAGLNSLKFGNIHNEKCSKHQKYLVKGVVNGISHYGNCMGVPTIGGECAFDECFNGNILVNAFALGVCKSEDIFYAKAEGVGNPVIYVGSKTGRDGLGGAVMASDSFNEESKSLRPTVQIGDPFSEKLLMEACLELFKTDYIVGIQDMGAAGLTSSSFEMAGRSGSGMKLYLDKTPIRESGMTPYELMLSESQERMLICAKKGYEDKVIEIFKKWDLDAVVIGEVTNTGKMELFWHDELVGLIPIEPLSEKAPILSRPISEPKYLSEIKDYKFELKLSIQELFIQMLQNENINNKAFIYDQFDSSVQTNTIKADGRLGASAIRIKENGASVAMAIECNSRLNYVNPKIGAALAVASAGRKVACTGAKPLAISDCLNYGNPQNPEVMWQFAQGCEGIKEACKELNTPVVSGNVSLYNETEGVSIYPSPTIVSVGVLEDANKTLKASFEKENLSVYLLGESLGEFGGSMVMKIQDKKVSGSLKELDYKAEIALWDLLYKANQNSLLECANSVGIGGIAMTLAKMFAISSVGANLTSGFDDEKMIFDESASRAIVGLSKENEEAFLNLAKEFGVKAYKLGVSTSQKHFKLDSIELSKAELDKLYFESFKEQIQ
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTB_HUMAN
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed:29581253).  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed:29581253).  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed:29925947).  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: RK22_ORYNI
Sequence: MTSFKLVKYTPRIKKKKSGLRKLARKVPTDRLLKFERVFKAQKRIHMSVFKVQRVLDEIRWRYYEETVMILNLMPYRASYPILKLVYSAAANATHYRDFDKANLFITKAEVSRSTIMNKFRPRARGRSSPIKKTMCHITIVLNIVKKSK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SEC11_YEASZ
Sequence: MNLRFELQKLLNVCFLFASAYMFWQGLAIATNSASPIVVVLSGSMEPAFQRGDILFLWNRNTFNQVGDVVVYEVEGKQIPIVHRVLRQHNNHADKQFLLTKGDNNAGNDISLYANKKIYLNKSKEIVGTVKGYFPQLGYITIWISENKYAKFALLGMLGLSALLGGE
What is the function of this protein?
Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity).  Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids (By similarity).
What are the official names of this protein?
Signal peptidase complex catalytic subunit SEC11, Secretory protein 11, Signal peptidase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26B family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: AGUA_LEGPL
Sequence: MNTAPKQYGFYMPAEWYPHERCWMAWPCHHETWSKIGLDKAKMAYARVAKAIAQFEPVTLLVNPGDEDSAKNLCKGHNIEIISLPINDSWTRDTGATFLINNERQLAGVDWIHNAWGGNYADCSLDNFIASHIIKYTEAQYFHAPLVMEGGSFHVDGEGTILTSKECLLNSNRNPHLSQQEIEQYLINYLGAERIIWLNMGLIGDETDGHVDEIATFIAPGKVLCLITKDKEDPNYHRLQENFEILKSSKDARGRTFEVYTVEQPPATYLNGERLTLSYINFYMANQGIVMPAFGYESFDRLAYQLFVQIFPGYQITQIDALDVFSGGGGIHCITQQQPKSHKLVEQ
What are the official names of this protein?
Putative agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: DCSTP_HUMAN
Sequence: MGIWTSGTDIFLSLWEIYVSPRSPGWMDFIQHLGVCCLVALISVGLLSVAACWFLPSIIAAAASWIITCVLLCCSKHARCFILLVFLSCGLREGRNALIAAGTGIVILGHVENIFHNFKGLLDGMTCNLRAKSFSIHFPLLKKYIEAIQWIYGLATPLSVFDDLVSWNQTLAVSLFSPSHVLEAQLNDSKGEVLSVLYQMATTTEVLSSLGQKLLAFAGLSLVLLGTGLFMKRFLGPCGWKYENIYITRQFVQFDERERHQQRPCVLPLNKEERRKYVIIPTFWPTPKERKNLGLFFLPILIHLCIWVLFAAVDYLLYRLIFSVSKQFQSLPGFEVHLKLHGEKQGTQDIIHDSSFNISVFEPNCIPKPKFLLSETWVPLSVILLILVMLGLLSSILMQLKILVSASFYPSVERKRIQYLHAKLLKKRSKQPLGEVKRRLSLYLTKIHFWLPVLKMIRKKQMDMASADKS
What is the function of this protein?
Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis.  Plays a role in TNFSF11-mediated osteoclastogenesis.  Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs).  Participates in osteoclast bone resorption.  Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors.  Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage.  Inhibits the development of neutrophilic granulocytes.  Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity.  Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.
What are the official names of this protein?
Dendritic cell-specific transmembrane protein, DC-STAMP, hDC-STAMP, Dendrocyte-expressed seven transmembrane protein, IL-four-induced protein, FIND, Transmembrane 7 superfamily member 4.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Endosome. Note=Localizes to the cell surface in osteoclasts and undifferentiated monocytes. Intracellular internalized DCSTAMP is detected in a fraction of RANKL-induced osteoclast precursor. Colocalizes with OS9 in the endoplasmic reticulum (ER) of immature dendritic cell (DC). Translocates from the endoplasmic reticulum to the intermediate/Golgi compartment upon maturation of DC in a OS9-dependent manner. Colocalizes with LAMP1 in endosomes (By similarity).
Protein: NHP6_CRYNJ
Sequence: MPKVSTKDSKKSTASDAKKRTKKDPNKPKRALSAYMFFVQDYRERIKTENPEATFGDVGKLLGIKWREMNENEKKPYEAKAKADKERADRENADYKAEGKASKKAAKADEESDDDE
What is the function of this protein?
DNA-binding protein that induces severe bending of DNA.  Required for DNA-binding by the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  Also augments the fidelity of transcription by RNA polymerase III independently of any role in the FACT complex (By similarity).
What are the official names of this protein?
Non-histone chromosomal protein 6.
What is the protein family that this protein belongs to?
Belongs to the NHP6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NAT9_CAEBR
Sequence: MKLNENVKIVAEKCVLVPYEPCHVEKYHKWMEDEEIRRLTGSERLSLEEEFEMQKSWREDDDKLTFIVLSREEGEETNRMLGDVNLFISKSENLEEEEDVGEVEVMIAEPRGRGKGIGQEAVSLIISWAFKNLQIARFCVKITEDNAPSLSLFEKKLGFKRVSYSSAFKEITMELPGERLESHFGRFLGENSQILEHK
What are the official names of this protein?
N-acetyltransferase 9-like protein.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNAT subfamily.
Protein: SYR_COXBU
Sequence: MIDLSTMKQQIETLLNQAIERLKTKGVLKPEVTPVIKITHTTDPQHGDFATNLALTLSKAAGMSPHALAEKIVEALPPSGQITEVEIAGPGFINFFVTEGSYQTVVSSILKAGKDYGRSEMGKGQRVHMEYVSANPTGPLHVGHGRGAAYGACVANLLNAAGFEVHREYYVNDAGRQMGILALSVWVRYLQGYEASIELPKNAYQGEYIIDIAEALKAKYGKQFYHSVESIQAKIPEEIDSNADPEAYLDVWVTAQKDLLGPKDFECVFQAALDSILNDIKNDLEEFGVTYDDWFPESRLVREGLIQEGLDLLTKHGYVYEKNGAQWFRATALGDEKDRVLIRKNGLPTYFAADVAYHLHKFNQGYDQIIDIFGADHHGYIPRIRGFLKGLGKAPEKLHILLVQFAILYRGNEKVSMSTRGGTFVTLRELRHEVGNDAARFFYIMRKPDQHLDFDLELAKSQSNENPVYYIQYAHARICSVFRQLKTTQKNWDRPRGMENLSLLSTNYEKELLATLGRYPEVIKRAAMNYAPHLLAHYLQTLANQFHTYYNAERFLIEDDNLRNARLNLINAVQQIIRNGLTLLGVSAPEEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_STAEQ
Sequence: MTKFIFVTGGVVSSLGKGITAASLGRLLKDRGLKVTIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTAGKVYSHVLKKERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFLEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMTQDLKDKIALFCDIKKESVIECRDADSLYEIPLQLSKQNMDDIVIQRLQLNAKYETQLDEWKHLLNTVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFKKDVVVKWIDSSEVNDDNVEAYLSDVDGILVPGGFGFRASEGKIAAIRYARENNIPFFGICLGMQLATVEFARHVLGYEGAHSAELDPSTPYPIIDLLPEQKDIEDLGGTLRLGLYPCHIKEGTLAEKIYNKNDIEERHRHRYEFNNEFREQLESNGMVFSGTSPDGRLVEIIEIPKNDFFIACQFHPEFLSRPNRPQPIFKSFVEAALNYQQK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: SYI_HAHCH
Sequence: MSDYKHTLNLPQTDFPMRGNLPQREPDMLKRWGDIELYEKIREEFKGREKFILHDGPPYANGNIHLGHAVNKILKDIIVKSKTVAGYDAPYVPGWDCHGLPIEHKVETMIGRAGDKVGYKEFRRKCREYALEQVAKQREDFIRLGVFGDWFKPYLTLDFKTEADIIRALGKIATSGHLQKGYKPVYWSVVGGSALAEAEVEYKDKTSNSIDVSYPAENEQDLLSAFADASGEGAVSIVIWTTTPWTLPASLAVSLGAEIDYALTQCSVDGRPQRWIVAEKMLESVMARCGVEDYQVVGRCTGQDLEGKTFLHPFYKRSIPALLGDHVTLDAGTGVVHTAPDHGMEDFAVCNKYGIETINPLDDRGVYRDNVELFAGEHVYKVDDHVIEVLKERGRLLSHGKITHSYAHCWRTKTPLIYRATPQWFISMDKQGLRDQALAEIKLVRWVPSWGQNRIEAMIEQSPDWCISRQRTWGVPIAFFVHKETQELHPDTARLVEEVAKQVEKTGIDAWWDINAEDLLGADAQNYEKVTDTLDVWFDSGVTHSAVLEQREELGQFPADLYLEGSDQHRGWFQSSLKTAVAIKGKAPYRQVLTHGFTVDEKGHKMSKSLGNGIEPQEVMNKLGADILRLWVAATDYSAEMVLSKNILERTADSYRRIRNTSRFLLANINDFDPVKDMVAMDDLLALDRWIVDRAWLLQEELKKAYEQYNFVQVYQKVHNFCSVELGSFYLDVIKDRQYTMKLDSLGCRSAQTAQYHVIEALVRWIAPILSFTAEEIWSYIPGQRAESIFLETFYEGLQPLAEGSEMGRDYWSRLLRVRTSVNKALEEARNAGKVKGSLTTEVSLFATPEMQHDLNALGEELRFVFITSGASVFGVEDASESNSVATETEGLRVGIRSSEHKKCGRCWHHREDVGAHGSHEDLCGRCIENIDGSGEERKYA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_BACP2
Sequence: MKKITVLGAGSWGTALALVLADNHHDVHMWGHRQELIDQIDEKHENHDYLPNVALPASIKATTDMKQALEGTDAIIVAVPTKAIREVLKRANELITSKVPFVHVSKGIEPDTLLRISQMIEQEVPDEKREAVVVLSGPSHAEEVGLRHPTTVTVSSENIEAAQFVQDLFMNNNFRVYTNPDVIGVEIGGALKNIIALAAGITDGLGYGDNAKAALITRGLAEIARLGTQMGGNPLTFAGLTGVGDLIVTCTSVHSRNWRCGNLLGKGYKLEEVLEKMGMVVEGVRTTKGAYQLSKEYKVSMPITEALYHVLFEGKKVDDAVESLMARVKTHEMEDLVNMFENQTK
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMD_VIBCM
Sequence: MARFFQPKKHSTLDTKHQPVTIERLDHQGSGLAFLHKKPLFVDGALPGEEVLIQLTENKSKYARGQLIKVLKPSAERVAPFCAHYAQCGGCDLQHLDRAGQIHHKQQALSQLMVKFAGQSLALSAPVCSDDQGYRRRARLSLMWDKKTQQLQLGFRRKQSKAIVNVTHCPVLEPSLNALLPDLNALLSEWSQPERLGHVELVKGDNTRVLVLRHLGALIEQDQQRLTDFASQNQLTLYLMLEAGELQHVQGEAPYCEETGSRLSFLPSHFIQVNRAVNQHMVVQALNWLEVSPQERVLDLFCGLGNFTLPLAKQAQAVVGVEGVDEMVQHATHNAKLNQINNVAFYQANLEQDMTSASWAQQKFAKVLLDPARAGAEGIVDQLSALGAKRVVYVSCNPATLARDSQSLLSQGFRLEKLGMLDMFPHTSHLESMALFVKKG
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: CML13_ARATH
Sequence: MGKDGLSDDQVSSMKEAFMLFDTDGDGKIAPSELGILMRSLGGNPTQAQLKSIIASENLSSPFDFNRFLDLMAKHLKTEPFDRQLRDAFKVLDKEGTGFVAVADLRHILTSIGEKLEPNEFDEWIKEVDVGSDGKIRYEDFIARMVAK
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML13, Calmodulin-like protein 13.
Protein: TUSD_PECAS
Sequence: MLSYCLLVTGPAYGTQQASSALQFAQALLAEGHKLESVFFYREGVLNANQLTSPANDEFDLVRGWQQLGDVHQVALNVCVAAALRRGIADSQQATQLNLVGANLQPGFILSGLGELAQSVLTYDRVIQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BXF1_BOMMO
Sequence: MKLVVIVLLVISVSILVSAQELGGSRRYCGRHLAQTMAVLCWGIDEMSAEKRNSDMVYEDSGMPELLPADTRKKRGIIDECCLQACTRDVLLSYC
What are the official names of this protein?
Bombyxin F-1, BBX-F1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: EYA1_CAEEL
Sequence: MLPDSEGQKLKTFLLGTGTTLDPSLDPTGNSNFSMATTSDSSTIWTALPASQPGDKDIPTVDLAAISEAYGSTSSTTSLTSSVTSQYQYNSYPQYAMYTSANPANYYQQVTANLRAGTTAFPYSLTTPSYYGSYPVDYTSAAAAYQNPYYTNLRGGTAAPYYNPLNATTAAAYASVASSVLGTDAVNLGTSSDGSTGVPSTVTSFSLKEKKPKVSKKKKTGSCSPGDETYARVFIWDIDDIAVISRNYLASVTHTNEFYARAANSVSHLMERIALNNFADVNEFLEGDITNIEDAVVDETTMDSGPIDNLRGLDVMRRVAPKYSAFRQFYTENSTKNDVAGFKQEQNGFNFELLERVGFGAREATELYQSAIQLQTLPNFGQRWPCAQRCMDLVVEKSKLSAEKYANVVLSNDGLVLGAAQLMISGLNSSVPVENIYSISKQGKESVFEKIQSRFGKKCSFICITSGDTANSAKRLNIPVWPLNSNTDLDKLYSALDNFLLGG
What is the function of this protein?
Tyrosine protein phosphatase (By similarity).  Acts probably as a transcription regulator in the embryonic and postembryonic development of several tissues including pharynx, vulva and gonads (PubMed:16154558).  Required for the development of anterior tissues during late embryogenesis (PubMed:16154558).  Together with ceh-34, required to specify the coelomocyte fate in embryonic and postembryonic precursors (PubMed:19427847).  In the anterior part of the embryo, prevents apoptosis in cells that are not fated to die (PubMed:16154558).  Together with ceh-34 activates proapoptotic factor egl-1 expression to promote motor neuron M4 sister cell apoptosis (PubMed:20713707).  Also promotes apoptosis of I1 pharyngeal neuron sister cell (PubMed:20713707).  Plays a role in locomotion and fertility (PubMed:16154558).  May play a role in resistance to heat and oxidative stresses (PubMed:25108328).  May cooperate with the transcription factors vab-3 and ceh-32 to repress transcription factor ets-5 expression in non BAG neuronal cells (PubMed:30890567).
What are the official names of this protein?
Eyes absent homolog 1.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. EYA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHF1A_ARATH
Sequence: MSNFTYTSAFNLSDNSPFNPAIGSSSSSSSALVVASDDDNNTDDACSICLEPFTLQDPSTVTSCKHEYHLQCIIEWSQRSKECPICWQLFVLRDPASQELLAAVEKERLLKTRNISSSSPISIHHSHDDFHSEEEESQFSSFDEQFLRHLTEAAHRRCLLRRRDGQISSSLVSSSDPTTIHPTDLVNLYRLSAISHVEHQNSNPCPSPGSMTPSPVSGHSSIPADSNNGSRISPGPSPSRSSQSPKSPEASSLPEAIKSKLAAASAKYKESISKSKQGLKEKLLARNNSVKELSKGVQREMNAGIAGVARMIERMDFSSKRFGGSAHVSTSTATASGFNFSFKGKRVEANSKSNNNGDKTEPQKLQGGETC
What is the function of this protein?
E3 ubiquitin-protein ligase involved in the positive regulation of the gametogenesis progression.  Mediates the proteasomal degradation of KRP6, a cyclin-dependent kinase inhibitor which accumulates during meiosis and blocks the progression of subsequent mitoses during gametophyte development.  Functions in association with RHF2A (PubMed:18552199).  Possesses E3 ubiquitin-protein ligase activity when associated with the E2 enzyme UBC8 in vitro (PubMed:15644464).
What are the official names of this protein?
E3 ubiquitin-protein ligase RHF1A, RING-H2 finger F1a, RING-H2 zinc finger protein RHF1a, RING-type E3 ubiquitin transferase RHF1A.
Protein: RLMI_YERPN
Sequence: MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_FRAAA
Sequence: MVFAAIPSPSRGVVHLGPVPLRAYALMIIIGIVVAVVVTGRRLRARGMDPALAGEIAYWAVPFGIVGARIYHVLSTPDAYFGEHGHVADVVKIWNGGLGIWGAIAGGALGAWLAARRLGISLALFADAAAPGIILAQAIGRWGNWFNQELYGKPTTLPWAVRIDPAHRADPGVATYQPTFLYEFLWNLVVAAILLLVDRRHRLGRGRLFALYVALYTFGRLWIEMLRIDTADEILGLRVNIWTSAIVCVGAVVALLVVRRPVDPDVSPQEQRALGLVQDRTRRQPTDAAGETAGETRTATRHDDATDGVDVNGADVDGADPSNVNGANVNGADPVNVNVNDADGAGAGAGEQPVAGAENGAAAVSSGRTRVERPPAT
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NBPF8_HUMAN
Sequence: MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFVNLKEMFSNSTGRLPGQPTEEIQQYKVLVHSQERELTQLKEKLREGRDASRSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKIGRGRRSKKKRRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDRCYSTPSMYCELRDSFQHYRSVF
What are the official names of this protein?
Putative neuroblastoma breakpoint family member 8.
What is the protein family that this protein belongs to?
Belongs to the NBPF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGR3L_HUMAN
Sequence: MGESAAATASLFQRRRRGRGGRVTFPGGLKGSARFLSFGPPFPAPPAPPFPAAPGPWLRRPLFSLKLSDTEDVFPRRAGPLEVPADSRVFVQAALARPSPRWGLALHRCSVTPSSRPAPGPALALLREGCPADTSVAFPPPPPPSPGAARPARFSFRLRPVFNASVQFLHCQLSRCRRLRGVRRAPAPLTPPPPPPPSRCLPQDEACADTGSGSAEGLAADGPHLHTLTQPIVVTVPRPPPRPPKSVPGRAVRPEPPAPAPAALEPAPVVALVLAAFVLGAALAAGLGLVCAHSAPHAPGPPARASPSGPQPRRSQ
What are the official names of this protein?
Transforming growth factor-beta receptor type 3-like protein, TGF-beta receptor type-3-like protein, TGFR-3L, Transforming growth factor-beta receptor type III-like protein, TGF-beta receptor type III-like protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TRUB_CALS4
Sequence: MSVDGVLNVLKPPGMTSHDVVDFIRKIYGIKKVGHTGTLDPDAAGVLPVCMGRATKFTSYLMEHDKRYRFEITFGFSTDTLDKSGKIVESGPVPLFTLEKLQEVLSQFKGEIQQIPPIYSAKKVKGKKLYEYARKGEEVEIPPIKVTVYELELIKYDAPHHLLLDVKCSKGTYVRALVRDICKKLEVPGHMSFLIRTEVGDFDIESSYTLEEIKEGKAEVQPVDKFIKFPSVELDEVSSNKILNGQFIRNTYNVENSLVKLYDNHGIFIGIGVAEGEKIRPKRLF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: BGL07_ARATH
Sequence: MKPFSQFFVFVVTVSATSYIDAFTRNDFPNDFLFGAATSAYQWEGAFDEDGKSPSVWDTTSHCDSGSNNGDIACDGYHKYKEDVMLMAEMGLESFRFSISWSRLIPNGRGRINPKGLLFYKNLIKELRSHGIEPQVTLYHYDLPQSLEDEYGGWINRKIIEDFTAFADVCFREFGEDVKLWTKINEATLFAIGSYGDGMRYGHCPPMNYSTANVCTETYIAGHNMLLAHSSASNLYKLKYKTKQRGSVGLSIYAYGLSPYTDSKDDETATERAEAFLFGWMLKPLVVGDYPDIMKRTLGSRLPVFSEEESKQVKGSSDFVGVVHYNTFYVTNRPAPSLVTSINKLFFADIGAYLIAAGNASLFEFDAVPWGLEGILQHIKQSYNNPPIYILENGKPMKHGSTLQDTPRAEFIQAYIGAVHNAITNGSDTRGYFVWSMIDLYELIGRYMTSYGMYYVNFSDPGRKRSPKLSASWYTGFLNGTIDVASQDTIQLQRKCSGSSSL
What are the official names of this protein?
Beta-glucosidase 7, AtBGLU7.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.