PharMolix/UniProtQA huggingface dataset:
Protein: RF1_STRPN
Sequence: MNIYDQLQVVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNRDTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGGFKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIRARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKLDEVVDALVLYDQTQKLEELNK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSCB_ARTBC
Sequence: MKSRVYVRFDRGFHVICPYQAKLAGSRKNDGAGYISPLALKSPIGLQHDLEDGCRIRSAFGKCIVNSRFLALIDVRKSGFKERGSKEPHGNSFVYWVTYSFLQFFETTMDELPSGRGMGGRLPFNQSFWEEFLSGREGQLPTLPDISHVSKSVIRILGGNPGSMHLQGTNTYLVGTGRSRILIDTAQGLPVWIDCISSFLHTQKIELSYVLLTHWHGDHTGGVPDLIAQNSSLADKIYKNHPDSGQNPITHGQIFSVDGATVRAIFTPGHSVDHMCFLLEEENALFTGDNVLGHGFSVAQDLGRYMDSLRDMASLGCRIGYPAHGAVIENLPGKLEEYIQHREGRERMMLSALTRQRVRGEGLREEGVKCGLTLNEIVMAIYGKLPPEVIEKALAPSLLQVLWKLTEDRMVGFKPGDPLKRQWFALEQRKRNKARGYPS
What is the function of this protein?
Lactamase-like protein; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
Lactamase-like protein nscB, Neosartoricin B biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: RSMH_SALNS
Sequence: MMENFKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAQAINDPRFSIIHGPFSALADYVAERELTGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTFGEERFAKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLSVLAPGGRLSIISFHSLEDRIVKRFMREQSRGPQVPAGLPMTEAQLKKLGGRELRALGKLMPGEKEVAENPRARSSVLRIAERTNA
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOY_LIMRJ
Sequence: MTFKVYYQADKTKRPVRENTQSLYIEADSEAEALLMVEHNTDYNIEFVEQLDEKALAYEKQNPNFKLTTF
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: ACUK_NEOFI
Sequence: MKTEDNGSAPALAGDHGGVDQDTPDAGDRTEQAKHKTNGTTEKAPKSSNAKDPSRPRRKKARRACFACQRAHLTCGDERPCQRCIKRGLQDACHDGVRKKAKYLHDAPDGALMPGVGGNFYNNAMRNNLPLSRNGATTVNTTSQQNSGSSYYPTPQSNSYNVYQDTPLTQNSFPSQSPVSPTFNMKTTPTARSNSLSSSVNQQPPNTTVSGATQSQNPFAGPFFDPSDPALFNFDLSSMNFENRYGALEFGMLGHMATGAGDSPTDSATQRGSMGRSGSTQYSTTPITGAPGFGESPGNQQPFMFGNDPLLNEWPNSQAPNQGHLNVSGVYPQGGMMHMAKSDAPHAFAIESGPASFSSPSATTSPHINSGYDESSLSNTVVNKSNGLTANGQRPAITTPSLKHQSLQFGVKRRQRNPSTVYESVKEPYAYTNRFHNLTAFIQRRFSPQKTLQIAKALASIRPSFIATTKTLNRDDLIFMEKCFQRTLWEYEDFINACGTPTIVCRRTGEIAAVGKEFSILTGWKKDVLLGKEPNLNVNTGGSSAPGSGTTSRGSFTPRSSTLENATPGRPQPVFLAELLDDDSVVEFYEDFARLAFGDSRGSVMTTCKLLKYKTKEDMELAQSDDNQRWNNHLRKGGIAGEAGMNQLGFKDGKVECAYCWTVKRDVFDIPMLIVMNVSCQCF
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis acuK.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSTB1_STRPN
Sequence: MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGKSTLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTIYENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVARVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTGFFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BH013_ARATH
Sequence: MNIGRLVWNEDDKAIVASLLGKRALDYLLSNSVSNANLLMTLGSDENLQNKLSDLVERPNASNFSWNYAIFWQISRSKAGDLVLCWGDGYCREPKEGEKSEIVRILSMGREEETHQTMRKRVLQKLHDLFGGSEEENCALGLDRVTDTEMFLLSSMYFSFPRGEGGPGKCFASAKPVWLSDVVNSGSDYCVRSFLAKSAGIQTVVLVPTDLGVVELGSTSCLPESEDSILSIRSLFTSSLPPVRAVALPVTVAEKIDDNRTKIFGKDLHNSGFLQHHQHHQQQQQQPPQQQQHRQFREKLTVRKMDDRAPKRLDAYPNNGNRFMFSNPGTNNNTLLSPTWVQPENYTRPINVKEVPSTDEFKFLPLQQSSQRLLPPAQMQIDFSAASSRASENNSDGEGGGEWADAVGADESGNNRPRKRGRRPANGRAEALNHVEAERQRREKLNQRFYALRSVVPNISKMDKASLLGDAVSYINELHAKLKVMEAERERLGYSSNPPISLDSDINVQTSGEDVTVRINCPLESHPASRIFHAFEESKVEVINSNLEVSQDTVLHTFVVKSEELTKEKLISALSREQTNSVQSRTSSGR
What are the official names of this protein?
Transcription factor bHLH13, Basic helix-loop-helix protein 13, AtbHLH13, bHLH 13, Transcription factor EN 39, bHLH transcription factor bHLH013.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLC3_YEAST
Sequence: MRFLQVYKSSALIGLIILLASKVNLAEAKRKLVATSLVTCMENSQLSANSFDVVFNPDDRSLHYDLDMSTQIDSYIFADIDVYAYGFKIITKNVDLCSINWKQFCPVHPGNIQIDSIEYISSEYVNEIPGIAYQVPDIDAYARVKITNNVSEYLACIQIYFSNGKTVSQIGVKWATAVVAGIGLLLSAILSTFGNSTAASHISANTMSLFLYFQSVVVVAMQHVHRVPPIAAAWAENLVWSMGLIRISFMQRIFRWYVQSTGGTPSLYLTSTSMSVLAQRSWQYLMELPLIKRATNVLYGNANTLIFRGIKRLGYKMGIENTSIVCTGFTFFVLCGYVLAGFIIVFKCCVELATRLGWIQKARFWEFRKQWRMILKGALLRYIYIGFVQLTILSFWEFTERDSPAVIVIACLFILLSCGLMLWAAWRTVFFARRSVALYNNPAALLYGDEYVLHKYGFFYTMFNANHYWWNIVLLSYIFVKSLLVGFAQASGQTQVLFMFILDLFYFVAIIYYKPYLDRPTNIMNILIATVTVVNSFLFMFFSDLFNQSYKVAAIMGWIFFIMNAAFSFILLMMILAFAGMMLFSKNPDLRFKPAKDDRTSFQRNTMKPEGTVNRSVANELLALGNVAKDHDDNSDYESNDTGVNDELKQAQDETTPTTVTSSDDNKPTFSEKILSKFSRPKNENASTDALRVEAPKQQTFPHNLTNLSRENLSTLGSKPYPGHTRSQSDAHNGLINSFEEEDTSSNTDPFHDSTEGDLLDTSSSDGGFRSQNYVRDDSINSLGNNKQPLRKPPGFFDEGFM
What is the function of this protein?
May be responsible for the transport of FAD into the endoplasmic reticulum lumen, where it is required for oxidative protein folding.
What are the official names of this protein?
Putative flavin carrier protein 3, FAD transporter 3, TRP-like ion channel FLC3.
What is the protein family that this protein belongs to?
Belongs to the transient receptor potential (TRP) ion channel family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SAMD1_RABIT
Sequence: MAGPPALPPPETAAAATTAAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERICRMVRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGGPAAAAAPPPTPAPPPPPAPVAAAAAPARAPRAAAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAAAPPAGPRRAPPPAAAVAARESPLPPPPQPPAPPQQQQQPPPPPPPQQPQPPPEGGAARAGGPARPVSLREVVRYLGGSSGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARAARNKRAGEERVLEKEEEEEEEEDDEDDDDDVVSEGSEVPESDRPAGAQHHQLNGGERGPQTAKERAKEWSLCGPHPGQEEGRGPAAGSGTRQVFSMAALSKEGGSASSTTGPDSPSPVPLPPGKPALPGADGTPFGCPAGRKEKPADPVEWTVMDVVEYFTEAGFPEQATAFQEQEIDGKSLLLMQRTDVLTGLSIRLGPALKIYEHHIKVLQQGHFEDDDPEGFLG
What is the function of this protein?
Unmethylated CpG islands (CGIs)-binding protein which localizes to H3K4me3-decorated CGIs, where it acts as a transcriptional repressor.  Tethers L3MBTL3 to chromatin and interacts with the KDM1A histone demethylase complex to modulate H3K4me2 and H3K4me3 levels at CGIs.  Plays a role in atherogenesis by binding with LDL on cell surface and promoting LDL oxidation which leads to the formation of foam cell.
What are the official names of this protein?
Atherin, Sterile alpha motif domain-containing protein 1, SAM domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Secreted. Note=In atherosclerotic lesions, it is found in the extracellular compartment and in foam cells cytoplasm.
Protein: NQRC_CHLMU
Sequence: MASKSRHYLNQPWYIILFIFVLSLVAGTLLSSVSYVLSPIQKQAAEFDRNQQMLMAAQIISYDNKFQIYAEGDWQPAVYNTKKQILEKSSSTPPQVTVATLCSYFQNFVRVLLTDSQGNLSSFEDHNLNLEEFLSHPTSSVQDHSLHVIYAILANDESSKKLSSSQVAKNPVSIESIILPIKGFGLWGPIYGFLALEKDGNTVLGTCWYQHGETPGLGANITNPQWQQNFRGKKVFLASSSGETDFAKTTLGLEVIKGSVSALLGDSPKANSAVDGISGATLTCNGVTEAFANSLAPYRPLLTFFANLNSSGESHDNQ
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit C, Na(+)-NQR subunit C, Na(+)-translocating NQR subunit C, NQR complex subunit C, NQR-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the NqrC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MTNN_BACLD
Sequence: MKIAVIGAMEEEVTILRSKLEQTNREVIANCEFTSGFYEGKEVVLLKSGIGKVNAAMSTTILLDRFKPDVVINTGSAGGFHHSLNVGDIVISTEVRHHDVDVTAFDYEYGQVPNLPAAYKADNALIQAAEDEASELGHIQVVKGTIATGDSFMSDPDRVAFIRGKFEDLYAVEMEAAAVAQVSYQFNTPFVVIRALSDIAGKESEISFDQFLEQAAKHSTDLVLRMIKRIN
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: VKTK1_CYRHA
Sequence: MGTARFLRAVLLLSVLLMVTFPALLSAEHHDGRVDICRLPSDSGDCLRFFEMWCFDGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Serine protease inhibitor that inhibits chymotrypsin and blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1k, U15-TRTX-Hhn1k, Kunitz-type serine protease inhibitor hainantoxin-XI-11, HNTX-XI-11.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 03 (sub-Kunitz) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL9_CHLTE
Sequence: MKIILRKDVATLGDAGEVVTVKNGYANNYLIPQGYAIRATEGTLKALETEKKQQARKIELQRTNARELAAKIEQMTLKVLAKAGESGKLFGTVTAGDIAEALKAQGVDIDRRKIHLEAPIKALGKYEADAKLFMDITAKLSIEVEAEGASEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: XYNA_STRSQ
Sequence: MFRHHPTRGRRTAGLLAAALATLSAGLTAVAPAHPARADTATLGELAEAKGRYFGSATDNPELPDTQYTQILGSEFSQITVGNTMKWQYTEPSRGRFDYTAAEEIVDLAESNGQSVRGHTLVWHNQLPSWVDDVPAGELLGVMRDHITHEVDHFKGRLIHWDVVNEAFEEDGSRRQSVFQQKIGDSYIAEAFKAARAADPDVKLYYNDYNIEGIGPKSDAVYEMVKSFKAQGIPIDGVGMQAHLIAGQVPASLQENIRRFADLGVDVALTELDIRMTLPRTAAKDAQQATDYGAVVEACLVVSRCVGITVWDYTDKYSWVPSVFPGQGAALPWDEDFAKKPAYHAIAAALNGGSPAPGGNCTATYRVTSQWQGGFTAEITVGNDHTAPITGWTVTWTLSSGQSISHMWNGNLTVNGQDVTVRDVGYNGTLGGNGSTTFGFQGEGVADTPADVTCTPGRPSGTSA
What is the function of this protein?
Contributes to hydrolysis of hemicellulose, the major component of plant cell-walls.  Hydrolyzes xylan to xylose and xylobiose.
What are the official names of this protein?
Endo-1,4-beta-xylanase A, Xylanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
Protein: PHLC_CLONO
Sequence: MKKKFLKGLCCAFVISITCLGASSKAYGWDGKKDGTGTHSMIVTQAVKVLENDMSKDEPEIVKQNFKILQDNMHKFQLGSTYPDYDPNAYKLFQDHFWDPDTDHNFSKDNLWYLSYSIKDTAESQVRKFTALARNEWEKGNYEKATWYFGQAMHYFGDLNTPYHAANVTAVDSIGHTKYEGFAEKRKDQYRINTTGIKTNEGFYADALKNSNFDSWSKEYCKGWAKQAKNLYYSHSTMKHTNEDWDYSASHALKNAQMGTAGCIYRFLYDVSKDLLPTENHKINGLMVVIKTANEIAAGTDDYVYFGIERKDGTVQEWTLDNPGNDFEANQEDTYILKIKKPSIKFSDINRMWIRKANFTPVSDDWKVKGIKVIADGSVQYEKQINKWIHGNEKYYIN
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture.  Binds to eukaryotic membranes where it hydrolyzes phosphatidylcholine, sphingomyelin and phosphatidylethanolamine.  The diacylglycerol produced can activate both the arachidonic acid pathway, leading to modulation of the inflammatory response cascade and thrombosis, and protein kinase C, leading to activation of eukaryotic phospholipases and further membrane damage (By similarity).  This enzyme is hemolytic against horse erythrocytes.
What are the official names of this protein?
Phospholipase C, PLC, Gamma-toxin, Phosphatidylcholine cholinephosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the bacterial zinc-metallophospholipase C family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS7_HALWD
Sequence: MSESDTDPDIDDDAHNNGDNDVDVAVDESESAETTTDTDTASANAKLFGEWDVSEIEYEDPSTQRYITVTPIAHTMGRHAAKQFEKSKISVVERLINRLMQTEDNTGHKQKTMNIVEDAFDTIHNRTEENPVQVLVRGVENAAPREETVRLKYGGISVPQAVDVAPQRRVDQALKFIADGTQRGSYKSAQSAADSLAQVIIGAANYDVQSYAVGQKEESERVAEAAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TPX_STAAN
Sequence: MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSEASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDVDNKVVYKEIVSEGTDFPDFDAALAAYKNI
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: TWST1_PONPY
Sequence: MMQDVSSSPVSPADDSLSNSEEEPDRQQPPSGKRGGRKRRSSSRRSAGGGAGPGGAASGGVGGGDEPGSPAQGKRGKKSAGCGGGGGGGAGGGSSSGGGSPQSYEELQTQRVMANVRERQRTQSLNEAFAALRKIIPTLPSDKLSKIQTLKLAARYIDFLYQVLQSDELDSKMASCSYVAHERLSYAFSVWRMEGAWSMSASH
What is the function of this protein?
Acts as a transcriptional regulator.  Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction.  This interaction probably involves the basic domains of both proteins.  Also represses expression of pro-inflammatory cytokines such as TNFA and IL1B.  Regulates cranial suture patterning and fusion.  Activates transcription as a heterodimer with E proteins.  Regulates gene expression differentially, depending on dimer composition.  Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression.  Heterodimerization is also required for osteoblast differentiation.  Represses the activity of the circadian transcriptional activator: NPAS2-BMAL1 heterodimer (By similarity).
What are the official names of this protein?
Twist-related protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK36_RHDSA
Sequence: MKVVSSIGSLKNRSKDCQVVKRRGRLYVICKSDPRLKVRQGGAKMKRK
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRMI_THET2
Sequence: MAWPGPLLLKDRKGRAYLVFPKEGGVFHHHKGSVPHEALLEAGPGGVVRTHLGEELSVHRPTLEEYLLHMKRSATPTYPKDASAMVTLLDLAPGMRVLEAGTGSGGLTLFLARAVGEKGLVESYEARPHHLAQAERNVRAFWQVENVRFHLGKLEEAELEEAAYDGVALDLMEPWKVLEKAALALKPDRFLVAYLPNITQVLELVRAAEAHPFRLERVLEVGWREWEVRLPVAHPRFQQVGHTAFLVALRRWKAS
What is the function of this protein?
Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.  Is required for cell growth at extreme temperatures.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase TrmI, tRNA(m1A58)-methyltransferase, tRNA(m1A58)MTase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
Protein: RSMH_YERPA
Sequence: MVDNNKTVDNNYKHTSVLLDEAVKGLNIRDNGIYIDGTFGRGGHSRLILSQLGPEGRLIAIDRDPEAIEAAKQITDPRFSIVHGPFSDLAHYVRDLDLVGRIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPSRGLSAAEWLMKASADDIAWVLKTFGEERFAKRLAKAIVERNLTQPMTRTKELADLIANASPFRDKHKHPATRSFQAIRIYINSELEEIERALDGAHEVLAPEGRLSVISFHSLEDRIVKNFIRHHSRGPQVPAGLPLTEAQLRSMGGRTLKSVGKMMPGDAEIAENPRARSSVLRFAERIGE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORML3_AILME
Sequence: MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNTGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSVLIPKLPQLHGVRIFGINKY
What is the function of this protein?
Negative regulator of sphingolipid synthesis.  May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (By similarity).
What are the official names of this protein?
ORM1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the ORM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIS7_LACP3
Sequence: MRTATITRTTKETTITISLNLDQQSGIQIATGIGFFDHMLDAFAKHGRFGLTVDAQGDLDVDPHHTIEDTGIVLGECFKQALGDKAGIERFRSAFVPMDESLARAVVDLSGRAYLVFDAELTNQRLGGFDTEVTEDFFQAVAFAGEFNLHASVLYGRNTHHKIEALFKALGRSLRAAVAINPEVQGIPSTKGVI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCPA_STAAM
Sequence: MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLARGLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNIDFTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAILCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPHRIEYRGTTK
What is the function of this protein?
Global transcriptional regulator of carbon catabolite repression (CCR) and carbon catabolite activation (CCA), which ensures optimal energy usage under diverse conditions.
What are the official names of this protein?
Catabolite control protein A.
Protein: RS18_RICB8
Sequence: MSKNNTSETITRKPMERASKKVFFRRRKGCPLSVPNAPVIDYKNPELLIKFVSEGGRMLPSRITNVCAKKQRKLNNAIKIARILALLPFVFQAK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: GATA_RHOPS
Sequence: MTDLTSLTLAEARDGLARKSFTALELTEAHLTAIEAARGLNAFVLETPEQARKMAQAADAQIATGDGGPLAGIPLGIKDLFATKDTRTTACSKILGDFHPPYESTVTTQLWRDGAVMVGKLNNDEFAMGSSNETSCFGPVVNPWRRAGSETKLVPGGSSGGSAAAVAAGLCLGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGIVAFASSLDQAGPIARTVRDSAILLRSMAGHDPKDTTSVDRPVPNYETAIGASVKGMKIGIPKEYRLEGMPPEIERLWTQGAEWLKASGAELVEVSLPHTKYALPAYYIVAPAEASSNLARYDGVRYGARVNGRNIVEMYENTRAAGFGAEVKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKRDFEQCFDQGVSAILTPATPSAAFGIGEKGGADPVEMYLNDIFTVTVNMAGLPGIAVPAGADGQGLPLGLQLIGRPFDEETLFSLGEVIEQAAGRFTPKKWWA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.