PharMolix/UniProtQA huggingface dataset:
Protein: QUEE_CAUVC
Sequence: MTYSVKEIFLTLQGEGGQAGKAAVFCRFSGCNLWSGREQDRAKAVCTFCDTDFVGTDGENGGKFATAEDLAAAVEAQWTGGPDDRLVVCTGGEPFLQLDDAAIAALHARGFQIAVETNGTITAPAGVDWICVSPKADAPVVQTSGQELKLVFPQEKAMPERFAALDFERFYLQPMDGPDRDANTQLAVAYCLSHPQWRLSVQTHKYLGLP
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Queuosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: ATPL_CAMC1
Sequence: MKKIVFLILGLAAFAFGADGEMIRSYSVIAGGIGLGLAALGGAIGMGNTAAATISGTARNPGVGSKLMTTMFIALAMIEAQVIYALVITLIVLYANPMLG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACDH5_RHOJR
Sequence: MSENTRKVTVAVIGSGNIGTDLMIKVIRHSEVLQMGAMVGIDPDSDGLARARRLGVPTTSDGVQGLLQLPNFDEIDVIFDATSAKAHEANAALLEPLGKRLIDLTPAALGPFVVPAVNLDEHRDAANVNMVTCGGQATIPIVAAVSRVTPVAYAEIVASIASKSAGPGTRANIDEFTETTSHAIETVGGARRGKAIIILNPADPPLIMRDTVLCLISAPDPATHDAIRDSIQTMVDHVATYVPGYRLKQQVQITPVPDGQPVRTLLASGDAATPTHQVSVFLEVEGAAHYLPAYAGNLDIMTSAAVRYAESVADTIAAPTAAQGATR
What are the official names of this protein?
Acetaldehyde dehydrogenase 5, Acetaldehyde dehydrogenase [acetylating] 5.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: TXN1A_POERG
Sequence: RCLHAGAACSGPIQKIPCCGTCSRRKCT
What is the function of this protein?
Toxin that acts as an agonist on melanocortin receptors (MC1R, MC3R, MC5R, MC5R).  After binding to MC1R, the peptide activates the hMC1R/Gs pathway, but after binding to MC4R, it is not able to activate or antagonize the MC4R/Gs pathway.  Inhibits melanocyte stimulating hormone (MSH)-binding to human receptors (Ki=1. 8 uM to MC1R, Ki=19. 8 uM to MC3R, Ki=7. 1 uM to MC4R, Ki=10. 0 uM to MC5R).  This toxin is structurally unrelated to the natural agonists.
What are the official names of this protein?
NU-theraphotoxin-Preg1a, N-TRTX-Preg1a, NU-TRTX-Preg1a.
What are the subcellular locations of this protein?
Secreted.
Protein: ALR_LISMF
Sequence: MVTGWHRPTWIEIDRAAIRENIKNEQNKLPENVDLWAVVKANAYGHGIIEVARTAKEAGAKGFCVAILDEALALREAGFQDDFILVLGATRKEDANLAAKNHISLTVFREDWLEELTLEAPLRIHLKVDSGMGRLGIRTTDEARRIETTIAKDNQLQLEGIYTHFATADQLETSYFEQQLAKFQTILTSLKNRPTYVHTANSAASLLQPQIGFDAIRFGISMYGLTPSTEIKTSLPFELKPALALYTEMVHVKELAPGDSVSYGATYTATEREWVATLPIGYADGLIRHYSGFHVLVDGELAPIIGRVCMDQTIIKLPREFQTGSKVTIIGTDHGNTITADDAAHYLDTINYEVTCLLNERIPRKYIH
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: DEF2_ARAHY
Sequence: VQKRTIIMEKKMAGFCIFFLILFLAQEYGVEGKECLNLSDKFKGPCLGSKNCDHHCRDIEHLLSGVCRDDFRCWCNRKC
What is the function of this protein?
Probably has antifungal activity.
What are the official names of this protein?
Defensin 2.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
Protein: DAPB_RICTY
Sequence: MINIGLSGATGKMGKTIIEIIDQFKDCQISEKFNSTNNLNDLDNLCKNSDVIIDFSTPEVLEKLINYALKHNTKLVIGTTGLKKQHFKLLEKAAKTLPILYSANMSIGANLLNYLAKESTKILDDYDVEILEMHHRNKKDAPSGTALMLASTIAGIKELNITFNRGNRIKSKKEIGISSLRGGNVHGIHEIFFLDNDEIITLKHEALNKNSFAVGAIKSAIWLQDKPSALYSMQDIYKV
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K0319_RAT
Sequence: MVSPPGVLSSLLLLAAMAGGSSQQCSEGRTYSDAIISPNLESIRIMRVSHTFSVGDCTAACCDLPSCDLAWWFEGSCYLVNCMRPENCEPRTTGPIRSYLTFVRRPVQRSGQLLDYGDMMLGRGSPSGAWGDSLEDLRKDLPFLGKDGGPEETAEYSDDYKELERGLLQPSNQQDPRGSAEYPDWSLLPSSDGDFNASATGDNSAASTEKLQDLTPYPLDQEQLQSLNESTWSPTPRHSEMSSMWPSSVTASPTEEGLEGEETLQLQEQPNNSSGKKVPMPSHNPSPASLESSPTTVEKSSIFTVTPWSRDPGTPTFPASTVLPGLISPSWPLSPTTSRTVKALAVSAGDNLVLTLPNGEAELKASVEPAPPADTAYTYEWSLMSHPVDFQGKIKQENKPTLHLSQLSVGLYAFRVAVSGENAFGEGYVNVTVMPAARINQPPVAIVSPQIQELSLPLTSALIDGSQSTDDAEIVSYHWEEVDGPFLGEAFLDDSPLLRLSNLDPGNYTFRLTITDSDGATNSTTAALIIRGSLDYPPVANAGPNQTITLPQNTIILNGNQSSDDHQIVLYEWFPDPGGESKEMVMQGAQTPYLHLSELQEGEYTFQLMVTDSSGQQSTALVTLTVQAENNQAPVAVAGPDKELVFPVQSAMLDGSRSSDDHGIVCYRWEHIRGPSAVEMENVDKAIATVTGLQVGTYHFRLTVRDQQGLSSTSTLTVAVKKENNSPPRAQAGGRHVLMLPNNSITLDGSRSTDDRGIVSYLWIRDGQSPAAGDIIGSSDNGAALQLTNLVEGVYTFHLLVTDSQGASDSDTAIVEVLPDPKKDGMVELILQVGVEQLTEQQKETLVRQLAVLLNVLDSDVKVLKIQAHTDVSTVIVFYVQSGSPFKVLRAADVARNLHKRLSKEKGAFLLFKVLRIDTAGCLLKCSGHGHCDPITKRCICSQLWMENLLQRYMWDGESNCEWSVFYVAALALTLTVLTGAVTWVCICCCRRRKRTKIRKKTKYTILDNMDEQERMELRPKYGIKHRSTEHNSSLMVSESEFESDQDTLFSQERMERGVLKGSLNGSARSGVSFGYYSKDR
What is the function of this protein?
Involved in neuronal migration during development of the cerebral neocortex.  May function in a cell autonomous and a non-cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers.  May also regulate growth and differentiation of dendrites.
What are the official names of this protein?
Dyslexia-associated protein KIAA0319 homolog.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein.
Protein: RL28_ALIB4
Sequence: MSRKCAISGKGPMVGNNVSHAKNRTRRRFLPNIRTVRVTLEDGTTTKLRISAKELRTLKKHS
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: WRNXO_DROSE
Sequence: MERYLTKMPIKSKANEVPKKEAFAKKETPKVARKATKTDTPKELKDKENAGDDNTPKQTKGRPGRPAAKRKNLDTPDVKDEKIAMEEENPPKRRSSRLTRSTRSMAEDGSPSPEKEKPEKLPFIKYKGAIKYFTESQDIAASADDVLQWVEKQKDDVVPMAFDMEWPFSFQTGPGKSSVIQICVDEKCCYIYQLTNVKKLPAALVALINHPKVRLHGVNIKNDFRKLARDFPEVTAEPLIEKCVDLGLWCNEVCETGGRWSLERLTNFIAKKAMDKSKKVRMSKWHVIPLDENQLMYAAIDVYIGQVIYRELERREKVKIKNEEEFKEKNGDAAFKAMKTLGETFLTKINEVTL
What is the function of this protein?
Has exonuclease activity on both single-stranded and duplex templates bearing overhangs, but not blunt ended duplex DNA, and cleaves in a 3'-5' direction.  Essential for the formation of DNA replication focal centers.  Has an important role in maintaining genome stability.
What are the official names of this protein?
3'-5' exonuclease, Werner Syndrome-like exonuclease.
What is the protein family that this protein belongs to?
Belongs to the WRNexo family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNB_SALSV
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHTEKERESAEPEELIEPFLTRFVGKVQGKNDRLSIVPDHPLLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFVPWWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELADGRLQLTVAIADPTAWIAEGSKLDNAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPALACRMIIAADGTIDDDIAFFAATIESKAKLAYDNVSDWLENNGTWQPDNEGIAQQIRLLHRICLSRSEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGEAIARPQEDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTNTRFAAEIIDVSRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIARPAA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_FRAAA
Sequence: MLIRNYRGLLGTKLGMTQVWDANNRVVPVTVIKAGPNVVTQVKTPDSDGYSAVQLGYGEIDPRKINKPARGHFATSGVTPRRHLVELRTADAGNYRPGQELTGEVFAEGTVVDVTGTSKGKGFAGVMKRHGFKGLGAGHGVERKHRSPGSVGGCATPGRVFKGLRMAGRMGHARTTTPGLTIHAVDTERGFLLVKGAIPGPDGGLVFVRSAAKRPAPEAIAPAATVGAGEEVSA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PSBC_LOLPR
Sequence: MKILYSLRRFYHVETLFNGTFVLAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVLDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGLGSFLLVLKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGFICVFGGIWHILTKPFAWARRAFVWSGEAYLSYSLAALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLNRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLSTSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDLEPVLYMNPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CLPX_RHOBA
Sequence: MNAEYGVGARLPAKTSLIVIRRRRGTSPQCWTHKSKESCMPTKETSNSRRGSAATKKNAFCSFCRKSYRDVGPLVEGPGDVYICAECIDLCQSILDQEQRRRGPSKSLFSDIPSPRSIVEHLDNYVIGQGSAKRVLAVAVHNHYKRLSNGADGSNGEVEIEKSNILLAGPTGSGKTLLARSLARMLNVPFAIGDATTLTEAGYVGEDVENLLLKLLHAADFDVEAAQRGILYIDEVDKIGSTNGNVSITRDVSGEGVQQSLLKMLEGTVANVPPQGGRKHPEQQYIQLDTSNILFICGGTFVGIEEIIRRRLGHRTLGFGEGANVRNEQTPGELVAQVQTEDILKFGLIPELVGRMPVISYLQPLDLEGLIQVLTEPKNSLVKQYQALFAMENCELEFTEEALHAIAKKAVDKGVGARGLRGIMEDVMLDIMYDLPEQEAGKVYTIDEAIVTGKQDLFKMPTTKSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: HTPG_HELPY
Sequence: MSNQEYTFQTEINQLLDLMIHSLYSNKEIFLRELVSNASDALDKLNYLMLTDEKLKGLNTTPSIHLSFDSQKKTLTIKDNGIGMDKNDLIEHLGTIAKSGTKNFLSALSGDKKKDSALIGQFGVGFYSAFMVASKIVVQTKKVNSDQAYAWVSDGKGKFEISECVKDEQGTEITLFLKDEDSHFASRWEIDSVVKKYSEHIPFPIFLTYTDTKHEGEGDNQKEIKEEKCEQINQASALWKMNKSELKDKDYKEFYQSFAHDNSEPLSYIHNKVEGSLEYTTLFYIPSTAPFDMFRVDYKSGVKLYVKRVFITDDDKELLPSYLRFVKGVIDSEDLPLNVSREILQQNKILANIRSASVKKILSEIERLSKDEKNYHKFYEPFGKVLKEGLYGDFENKEKLLELLRFYSKDKEKLISLKEYKENLKENQKSIYYLLGENLDLLKASPLLEKYAQKGYDVLLLSDEIDAFVMPGVNEYDKTPFKDASHSESLKELGLEEIHDEVKDQFKDLMKAFEENLKDEIKGVELSSHLTSAVALIGDEQNAMMANWMRQMGQSVPESKKTLELNPNHAILQKLLKCEDKEQLSAFIWLLYDGAKLLEKGALKDAKSFNERLNSVLLKAL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT5B_CONLT
Sequence: MLCLPVFIILLLLASPAAPKSLETRIQNDLIRAGLTDADLKTEKGFLSGLLNVADSVCCKVDTSCCSN
What are the official names of this protein?
Conotoxin Lt5.11, Lt5k.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS2_METVS
Sequence: MRFELDGRIIFSKDVTKEAQIEILEVLENRDIFLKGVPEGKEGDASKIESYKFEGKDLVLKMTSGTYTRAHEGIVRLKKPIMEKIGRNHQIGIRDVTIDKYVITIDSEISKVEQLKGLKVPECELKLEGEKINIIFKNVGDGELKRNIIDRAIKFVKNELDKQDQDLTYEVCKIAPGTIVSEYQAQRKTGFFSDPTDLAESLGWVKKFPGRGQWFYTPPMAKLFRAFENLIIEECIQKIEFDECLFPKLIPLDVMYKMRYLEGLPEGMYYVCPPKREPEMFQDFVNEMMIKKEIPIDKLKELLRDPAYVLAPAQCEPFYTLFDHELVDIDSPVKFFDKSGWTYRWEGGGAKGLDRVNEFLRSECVWMGSPKFVEEVRDDTLKYAEDLAKKLDLEYWTEVGDDPFYLEGRKKDDRSIEFPDVPKYEMRLWLPHIKEERKGVAVTSANIHGTHFVEGFGIKDYKDRKVWTGCTGFGLTRWIIGFLAQYGFEYSDWPDMIKDKVLEMPKIPKMITWP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Type-2 serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STAG2_XENLA
Sequence: MNGHHQQNGVENMMLFEVVKMGKSAMQSVVDDWIEAYKHSKDVALLDLINFFIQCSGCKGVVSGEMFRHMQNSEIIRRMTEEFDEDSGDYPLTMAGPQWKKFKFSFCEFIGVLVRQCQYSIIYDEYMMDTVISLLTGLSDSQVRAFRHTSTLAAMKLMTALVNVALNLSINMDNTQRQYEAERNKMIGKRANDRLELLLQKRKELQENQDEIENMMNAIFKGVFVHRYRDAIAEIRAICIEEIGVWMKMYSDAFLNDSYLKYVGWTMHDKQGEVRLKCLTALQGLYYNRELNTKLELFTSRFKDRIVSMTLDKEYDVAVQAIKLLTLVLQSSDEVLTAEDCENVYHLVYSAHRPVAVAAGEFLYKKLFSCRDPEEDGIMKRRGRLSPNANLVKTLVFFFLESELHEHAAYLVDSMWDCATELLKDWDCMNSLLLDDPLNGEEALTDRQESALIEILLCTVRQAAECHPPVGRGTGKRVLTAKEKKSQMDDKTHLTELFAVSLPQLLAKYSVDAEKVTNLLQLPQYFDLEIYTTGRLEKHLEALLRQIRNIVEKHTDTDVLEACSKTYHALCNEEFTIYNRVDIAKSQLIDELADKFNRLLEDFLQEEEELDEDDAYQVLSTLKRITAFHNAHDLSRWDLFSGNYKLLKTGIENGDMPEQIVVHALQCTHYVILWQLAKFSETGSSKEELITLKRQMRVFCQICQHYLTNVNTAVKEQAFTILCDVLMIFSHQIVVGGREALEPLVYSPDSSLQSELLSFILDHVFIDQDDDNSSSDGQQDDEASKIEALHKRRNLLAAFCKLIVYNVVEMNTAADIFKQYMRYYNDYGDIIKETMSKTRQIDKIQCAKTLILSLQQLFNEMIQEHSYNFDRSSPTFSAIKELARRFALTFGLDQLKTREAIAMLHKDGIEFAFKEPSPQGEAHPPLNMAFLDILSEFSSKLLRQDKKTVYAYLERFMTFQMSLRREDVWLPLMSYRNSLLAGGDDDTMSVMSGMSGRGSSTRSKKIKPPTGKRKLPEAEESSSSDSMWLNREQTMNTPVMLQTPQLTSTIMREPKRLRPEESYMPVYPMQPEHHQPSLDYNTQVTWMLAQRQQEEAARQQQERAAMNYVKLRSNLQHAIRRNTGLMEDDEEPIVEDVMMSSEGRIEDLNEGMDFDTMDIDLPPSKNRRERTELKPDFFDPASIMDESVLGVSMF
What is the function of this protein?
Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication.  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.  The cohesin complex may also play a role in spindle pole assembly during mitosis.
What are the official names of this protein?
Cohesin subunit SA-2, xSA-2, SCC3 homolog 2, Stromal antigen 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of cohesin is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation.
Protein: LSPA_ECOL6
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCT1A_MOUSE
Sequence: MMTCPSVPAIPTLWLFSILLLVVSLNAQNKSWDNPICTEGILSVPRGNPAVMTCNISNTFTDVTIQLSANGKDKTIFDKKPQGNFSWRGWELQVQGGQAQLVIKDTQDDHTGIYLWQLHGRQRCYKNITLNILEPSNEDKVPDTTLFTSFPDHAKSSPIEGKPGTLVGVITVIFILGVAGFITFIYYRHRRS
What are the official names of this protein?
Secreted and transmembrane protein 1A.
What is the protein family that this protein belongs to?
Belongs to the SECTM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted.
Protein: SUCB1_CAEEL
Sequence: MIGRISQPLLNTSQKFMAPAARTLMLHEHHGMKILQNYEIKVPPFGVAQDAETAFSEAKRIGGKDYVVKAQVLAGGRGKGRFSSGLQGGVQIVFTPDEVKQKAGMMIGANLITKQTDHRGKKCEEVMVCKRLFTRREYYFSITLDRNTNGPIVIASSQGGVNIEEVAATNPDAIVKMPIDVNVGITKELAHEIAVKMGFSKDCEQQASEIIEKLYQMFKGSDATLVEINPMAEDVNGDVYCMDCKLLLDSNAEFRQAKLFDLKDKKQEDELEIRAAAANLNYIRLDGTIGCMVNGAGLAMATMDIIKLHGGEPANFLDVGGGATVEQVTEAFKIITADKDKVSAILVNIFGGIMRCDVIAQGIIQAARELDLKIPIVVRLQGTKVEDAKALIATSQLRILPCDNLDEAAKMVVKLSNIVDLARATNVDVKFELSI
What is the function of this protein?
ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, ATP-specific succinyl-CoA synthetase subunit beta, A-SCS, Succinyl-CoA synthetase beta-A chain, SCS-betaA.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DEOB_CLOK5
Sequence: MERVILIVFDSVGIGELPDAKEYGDVGSNTLGNISKAAGGLEIPTLYKLGIGNIQGVENLRRCEKPIGSFGKCAELSKGKDTVTGHWEMAGIVLKTPLNTYPQGFPEDIIEEFQVKIGRKVLGNKVASGTEIINELGKEHVDTGYPIVYTSADSVFQVAAHEKIIPVEELYKMCKIAREMLLGDRTVGRVIARPFIYDKGKYVRTSNRKDFALDPPGKTMLDYIKEVGLDVMAVGKIEDIYNKRGITEAVHIKNNMDGIDKTLGYMKKNKSGLIFANLVDFDMLYGHRNDTEGYAKALVEADKRIPEIISNMNEEDVLIITADHGCDPTTKSTDHSREYIPVLVYGKNLKAGVDIGIRKSYSDIGKTILELLDIKNNLQGIGFKDLINK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_HYDS0
Sequence: MEQLLEKALILQEALPFIRDFYGKVFVVKYGGAAMEEEELKHSFAKDIALLRYVGIKVVLVHGGGKDITNMLNKLNIQTEFINGIRKTDKESLDVARMVLIGKLNKDIVSMLNKEMSNMHGAIGLSGIDANLLICTKYYQDGEDIGYVGKVKTVNTKLIRELIQMDYTPVIAPIGIDPESNQMYNVNADMAATEIACELGAEKLIFLTDTDGILDKSGKTISSIHKNQYKELIEDGTITKGMIPKINSAIDAILRGVRKVHIINGKIKHSILIEVFTKEGIGTEISL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_HAEIE
Sequence: MQFSKMHGLGNDFVVVDGVTQNVFFTPETIRRLANRHCGIGFDQLLIVEAPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVTLKGLTNKKDIAVSTQKGNMVLTVKDDNQIRVNMGEPIWEPAKIPFTANKFEKNYILRTDIQTVLCGAVSIGNPHCVVQVDDIQTANVEQLGPLLENHERFPERVNAGFMQIINKEHIKLRVYERGAGETQACGSGACAAVAVGIMQGLLNNNVQVDLPGGSLMIEWNGVGHPLYMTGEATHIYDGFITL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLS24_STRP6
Sequence: MTETYIKNTSKDLTSAIRGQLTYDDKVIEKIVGLALENVDGLLGVNGGFFANLKDKLVNTESVRDGVNVEVGKKQVAVDLDIVAEYQKHVPTIYDSIKSIVEEEVKRMTDLDVIEVNVKVVDIKTKEQFEAEKVSLQDKVSDMARSTSEFTSHQVENVKASVDNGVEKLQDQKAEPRVK
What are the official names of this protein?
Stress response regulator gls24 homolog.
What is the protein family that this protein belongs to?
Belongs to the asp23 family.
Protein: HIS8_SHEAM
Sequence: MTSQVNAVPTDSLAARLARPELLSLEPYQSARRIGGSGEIWVNANESPFNRTGIDGANRYPECQPPGLIAAYAAYAGVAAHELVCGRGADEAIELLIRTFCVPGQDSIGIFSPTYGMYAISAATFNVAVNTLPLAEDFSLPDDISALTGSKLVFVCNPNNPTGTLLPLGEIARVAKTFPNALVVVDEAYIEFAHNADGSPAQSATSLMAEFENLVILRTLSKAFGLAGARCGFLLAKPSVCELVMRVIAPYPVPVPVSVIAEKALSVMGIAQMRADVVLLNKQGARLALALTEAGLSVLPSGGNYVLAFSNDVEVLARALTKAGIVARRYSHPRLKDAIRISYASEQQTDSIIEAIGRIDSK
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: HSLU_RICAE
Sequence: MKATKTTYKKDPMGLTPSQIVNELNRFIVGQEKAKKAVAIALRNRCRRKRVEGNLRNEIVPKNILMIGSTGVGKTEIARRLAKLTNSPFYKIEATKFTEVGYVGRDVESIIRDLVEIAVNTEKTLAKTKVDIHAREKAIERILDSLVGKTSSSETREKFKEKILNGELDDKEIEISVADTTPVGGGSFEIPGMPGASMGVLNLGDMIGRALGSSKTKTKKMLVKDAMAIIIPEESEKLIDQEKIIQQAINLAENDGIVFIDEIDKIASTGSSGAKNAAISREGVQRDLLPLIEGTTVNTKYGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELNSLTKDDMIKILLEPETSLIKQYSALIGTEDVRLEFAASAIEKIADYAITVNLEVEDIGARRLHTILENLLEDISFEASEMKGKKITIDDKFVENQLSKIITNLDLAKFVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPPC5_CHICK
Sequence: MESRFTRGKSPLLERPLGRPRGEVSLSAFALLFCELVQYCQRRVYSVAELQSKLAQLGHQVGLRLLDPLVSRERGGRRETKVLSVLLFVKGPVWRALFGKEADKLEQANDDDKTYYVIEREPLVNTFISVPRENSTLNCAAFTAGLVEAVLGASGFPAKVTAHWHKGTTLMIKFEEGVIARDKSLEGR
What is the function of this protein?
May play a role in vesicular transport from endoplasmic reticulum to Golgi.
What are the official names of this protein?
Trafficking protein particle complex subunit 5.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.