PharMolix/UniProtQA huggingface dataset:
Protein: RNB_SALAR
Sequence: MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHTEKERESAEPEALIEPFLTRFVGKIQGKNDRLTIVPDHPMLKDAIPCRAARGVQHEFKEGDWAVAEMRRHPLKGDRSFYADLTQYITFADDHFAPWWVTLARHNLEKEAPNGVATEMLDEGLERQDLTALNFVTIDSASTEDMDDALYAEELADGRLQLTVAIADPTAWIAEGSKLDNAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPTLTCRMIIAADGSIDDDIAFFAATIESKAKLAYDNVSDWLENSGTWQPDNEGIAQQIRLLHRICLSRGEWRHHHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANLCAARVLRDKLGFGIYNVHTGFDPANADALAALLKTHGLHVDAEEVLTLEGFCKLRRELDAQPSGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETIARPREDITQQMAERRRLNRMAERDVGDWLYARFLNDKAGTDTRFAAEIIDVSRGGMRVRLVDNGAVAFIPASFLHAVRDELVCSQENGTIQIKGETVYKVTDVIDVTIAEVRMDTRSIIARPAA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM20_YEAS7
Sequence: MGNASVAVGTAVGIPIAVGVIIALIFWCKLQRRYKKEEIRDADLEKMVMEEVAVSVYDGFKAEINSSSEASTINEKEANQDLKPCQEKTAKAGYTPAYRRQLNASMGTLRPKKQSTAYINVPVIFSGEKVNYGMVRDPSYSFMYPLTLSRKETSSLRSASTSNLSSSTENTALHEEIKLDDPYENDFTNYTVNKREFIDSLRPR
What is the function of this protein?
Involved in cell cycle progression and surviving DNA damage.
What are the official names of this protein?
Altered inheritance of mitochondria protein 20.
What is the protein family that this protein belongs to?
Belongs to the SKG1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: PDXH_YERPA
Sequence: MTENNEFDVADLRREYIRGGLRRSDLTENPLELFERWLKQACEARLPDPTAMCVATVDTNGQPYQRIVLLKHYDDQGLVFYTNLGSRKAQQLAENPHISLLFPWHMLDRQVIFLGKAERLSTLEVLKYFHSRPKDSQIGAWVSQQSSRISARGVLESKFLELKQKFQQGDVPLPSFWGGFRVKFDSVEFWQGGEHRLHDRFIYQREADAWKIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PSN2_PIG
Sequence: MLTFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQGLEDGESAAQWRSQDSEEDHEEDPDRYVCSGVPGRPPGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIYTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLITSSLMLLFLFTYIYLGEVLKTYNVAMDYPTLFLTVWNFGAVGMVCIHWKGPLVLQQAYLIMISALMALVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWTVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGYPGEELEEEEERGVKLGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISITFGLIFYFSTDNLVRPFMDTLASHQLYI
What is the function of this protein?
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein).  Requires the other members of the gamma-secretase complex to have a protease activity.  May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane.  May function in the cytoplasmic partitioning of proteins.  The holoprotein functions as a calcium-leak channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis.  Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria.
What are the official names of this protein?
Presenilin-2, PS-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase A22A family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: HMGX_ASPFU
Sequence: MASGTTIQPSRPSLTSNDSAVLQALFDAESSPSSAVAIDPSLSPFPEYLHISASDHESLKARELSIIRSLQSDDVSMDTITSAIRDLDALITEHPTYPSAYVNRAQALRLHIEKTAEASTDPEEAIFTPGNTESASRLFSDLGQAISLCTPRSPADPVSTVQARILADSHTHRGYLLLKAARLKKNANGNEMVGGPDKLRDMGPDQLEEMASRDFFFGGRYGNKVAQQLAVQTNPYAKMCGAIVKEALRKEVEGVI
What is the function of this protein?
Part of the L-tyrosine degradation gene cluster that mediates the biosynthesis of the brownish pigment pyomelanin as an alternative melanin (PubMed:19028908, PubMed:22046314).  The 4-hydroxyphenylpyruvate dioxygenase hppD catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisic acid (HGA) (PubMed:19028908, PubMed:22046314).  The protein hmgX is crucial for this conversion and thus, probably functions as an accessory factor to mediate specific activity of hppD (PubMed:22046314).  The homogentisate 1,2-dioxygenase hmgA is then involved in the cleavage of the aromatic ring of HGA and its conversion to 4-maleylacetoacetate (PubMed:19028908, PubMed:19715768).  When hmgA activity is lowered by the cell wall integrity (CWI) signaling pathway, HGA accumulates and leads to the production of pyomelanin through benzoquinone acetic acid after oxidation and polymerization (PubMed:19715768).  On the opposite, in non-stress conditions, both hppD and hmgA activities are balanced and HGA is degraded into 4-maleylacetoacetate (PubMed:19715768).  4-maleylacetoacetate is further converted to 4-fumarylacetoacetate by the maleylacetoacetate isomerase maiA, which is degraded into fumarate and acetoacetate by the fumarylacetoacetase fahA (Probable).
What are the official names of this protein?
L-tyrosine degradation gene cluster protein hmgX, Pyomelanin biosynthesis cluster protein hmgX.
What is the protein family that this protein belongs to?
Belongs to the TTC36 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF45_ARATH
Sequence: MAITKTSATFVLLIILAASLSNFNVLASDIKPTGRIDNQCKRMCSATYGNGKCAADCRSDGFSSGQCFTSPPFDNRCCCNN
What are the official names of this protein?
Defensin-like protein 45.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSX_WOLSU
Sequence: MVRVAIDAMGGDFGPAPIVEGTLLALNEKDFIPFLVGNKEIIEPLIPQKYKKTLEIIDCKDFIKMEEGASSAIRRKDSSIYVATELAKEGKVDALVSAGHSGATMSLATLRIGRIEGASRPAICAIMPRQDGKQSLILDAGANVDCKPEHLYEFALMGYEYSKNVMGYENPRIGLLSNGEEESKGNELTKSAFSRLKTLKGFVGNVEGHNIFDGSTEVIVCDGFVGNIVLKTSEGVAESITTLIKNFVKVSLTGVVGALFMKNVFKKLKKRMDYAEYGGAPLLGVNGNVIICHGKSNAKAIKNAIFQALTSVDQKINENIIKAFASHPSKE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: MTOX_ECOLU
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEEDPIFVRSGVINLGPADSTFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAKEAGCAQLFNCPVTAIRHDDDGVTIETADGDYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVASDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: RS12_ECOLU
Sequence: MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGALDCSGVKDRKQARSKYGVKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: FA5_BOVIN
Sequence: MFLACPGFWVLVVLGSSWAGWGNLGAEAAKLRQFYVAAQSIRWNYRPESTHLSSKPFETSFKKIVYREYEAYFQKEKPQSRTSGLLGPTLYAEVGDIMKVHFKNKAHKPLSIHAQGIKYSKFSEGASYSDHTLPMEKMDDAVAPGQEYTYEWIISEHSGPTHDDPPCLTHIYYSYVNLVEDFNSGLIGPLLICKKGTLTEDGTQKMFEKQHVLMFAVFDESKSWNQTSSLMYTVNGYVNGTMPDITVCAHDHISWHLIGMSSGPELFSIHFNGQVLEQNHHKISAITLVSATSTTANMTVSPEGRWTIASLIPRHFQAGMQAYIDIKNCAKKTRNPKKLTRDQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNRIGKHYKKVVYKQYQDDSFTKRLEDPSSEGDGILGPIIRAQVRDTLKIVFKNMASRSYSIYPHGVTFSPYDNEVNSSSTSGSNTMIRAVRPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDLASGLIGLLLICKSRSLDRRGIQRAADIEQQAVFAVFDENKSWYIEDNIYKFCENPEKVKRDDPKFYESNIMSNFTLPAINGYVPESIPILGFCFDDTVQWHFCSVGTQNDILTIHFTGHSFIYGKRHEDTLTLFPMQGESVTVTMDNVGTWMLTTMNSNPRSKKLRLRFRDAKCIRNDDDDSYEIIYEPSGSTAMTTKKIHDSSEIEDENDADSDYQDELALILGLRSFRNSSLNQEKDELNLTALALEKDSEFIPPSANRSLDSNSSSRSHVSRLIAKNFAESLKTLLHLEAPAAGSPLEHAGLDKNSALNPPMAEHSSPYSEDPREDHPLSDVTGVSLLPFGTGFKNRKPAKHQRFQVGRGQAAKHKFSQTRFPAHKTRTRLSQDNSSSSRMGPWEDIPSDLLLLQQKDPYKILNGEWHLVSEKGSYEIIQDANENKTVNKLPNSPQNDSRTWGENIPFKNSHGKQSGHPTFLVTRRKPLQDRQDRRNSRLKEGLPLIRTRRKKKEEKPAYHVPLSPRSFHPLRGEVNASFSDRRHNHSLLLHASNETSLSIDLNQTFPSMNLSLAASLPDHDQTSPNDTTSQTSSPPDLYPTVSPEEHYQIFPIQDSDPTHSTTAPSNRSPDPTHSTTAPSNRSPPTQPSQIPNYDLRNRAIPTDVSQIFPSLELEVWQTATSLDLSQPSISPDLGQMALSPDPGQESLSPDLGQTSLSPDLSQESLSPDLGQTALSPDPSQESLSPDLGQTALSPDPSQESLSPDLGQTALSPDPGQESLSPDLGQTSLSPDLSQESLSPDLGQTALSPDPSQESLSPDLGQTALSPDPSQESLSPDLGQTSLSPDLGQESLSPDLGQTALSPDPSQESLSPDLGQTSLSPDLGQESLSPDLGQTALSPDLSQESLSPDLGQTPLSPDLSLESLSPDLSQLDLKQTSPPLDLNQTSHTSESSQSLPLPEFGQTFPNADIGQMPSPPPDSTLNNTFIPEEFNPLVVVGLSRDDGDYIEIIPRQKEESSEEDYGEFEFVAYNDPYQTDLRTDINSSRNPDNIAAWYLRSNTGNRKYYYIAAEEISWDYSKFVQSDDVDYVPEDTVYKKVVFRKYLDSTFTKLDPQGEYEEHLGILGPVIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAIQPNKTYTYVWHATTRSGPENPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLDKETNMPVDMREFVLLFMVFDEKKSWYYDKKPTRSWRRASSEVKNSHEFHAINGMIYNLPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKASKPGWWLLDTEVGEIQRAGMQTPFLIVDRECKMPMGLSTGLIADSQIQASEFWGYWEPKLARLNNGGSYNAWIAEKLSTEFNPEPWIQVDMQKEVLLTGIQTQGAKHYLKPYYTTEFCVAYSLDRKNWRIFKGNSTRNVMYFGGNSDASTIKENQIDPPVVARYIRISPTGSYNKPALRLELQGCEVNGCSTPLGMESGKIENKQITASSFKKSWWGNYWEPFLARLNAQGRVNAWQAKANNNNQWLQIDLLKIKKITAIVTQGCKSLSSEMYVKSYTIHYSDQGTDWKPYREKSSMVDKIFEGNNNVRGHVKNFFNPPIISRFIRIIPKTWNQSIALRLELFGCDMY
What is the function of this protein?
Central regulator of hemostasis.  It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.
What are the official names of this protein?
Coagulation factor V, Activated protein C cofactor.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: CRLS1_CAEEL
Sequence: MIVTSMFRGIACRCELQLLLTPRRMLRNFSSLEQKQSPKIESLPPEERGKYKVATIPNAICTARIAATPLIGYLVVQHNFTPAFVLFTVAGATDLLDGFIARNVPGQKSLLGSVLDPVADKLLISTMFITMTYAGLIPLPLTSVVILRDICLIGGGFYKRYQVMSPPYSLSRFFNPQVSSMQVVPTMMSKINTVLQITLVALSLSSPVFDFSTGANDVIVGLGCITGFTTIYSGLQYASGKAIKKI
What is the function of this protein?
Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG).  CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.
What are the official names of this protein?
Probable cardiolipin synthase (CMP-forming), CLS.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SFSA_ECOSE
Sequence: MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGCATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELSGYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKHLRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAEISAEGMALKKSLPVTL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: S35B4_HUMAN
Sequence: MRPALAVGLVFAGCCSNVIFLELLARKHPGCGNIVTFAQFLFIAVEGFLFEADLGRKPPAIPIRYYAIMVTMFFTVSVVNNYALNLNIAMPLHMIFRSGSLIANMILGIIILKKRYSIFKYTSIALVSVGIFICTFMSAKQVTSQSSLSENDGFQAFVWWLLGIGALTFALLMSARMGIFQETLYKRFGKHSKEALFYNHALPLPGFVFLASDIYDHAVLFNKSELYEIPVIGVTLPIMWFYLLMNIITQYVCIRGVFILTTECASLTVTLVVTLRKFVSLIFSILYFQNPFTLWHWLGTLFVFIGTLMYTEVWNNLGTTKSEPQKDSKKN
What is the function of this protein?
Has UDP-GlcA:UDP-GlcNAc antiporter activity.
What are the official names of this protein?
Nucleotide sugar transporter SLC35B4, Solute carrier family 35 member B4, UDP-xylose and UDP-N-acetylglucosamine transporter, YEA4 homolog.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PRVB2_GADCH
Sequence: MAFAGILKDAEVAAALEACKSAGSFDHTKFFKSCGLAGKSSDDVKKAFGIIDQDQSDFIEEEELKLFLQNFSASARALSDAETKAFLKAGDSDGDGKIGVDEFAAMVKA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta-2.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: PANC_THISH
Sequence: MQTVHTRAALAAALDPWRRAGERIALVPTMGNLHAGHLALVRRARAEADRVVATIFVNPLQFDRPEDLAAYPRTLEADAAALAGAGVDLLFAPAEQEVYPRGRDGVTRVEVPGLGDELEGAHRPGHFIGVATVVCKLFAMTRPDVAVFGEKDFQQLLIIRTMNADLDLGVRVLSEPTVREPDGLAMSSRNGYLGPEDRARAPALHAALRALAGALERGERDFPALEQAARSQIEAAGLRPEYVSLRRRQDLDLPGPGDRELVILAAAWCGPARLIDNLPVDLPPSG
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANC_KLEP3
Sequence: MLIIESVLLLRQHIRRLRQEGKRIALVPTMGNLHDGHMKLVDEAKASADVVVVSIFVNPMQFDRADDLARYPRTLQDDCEKLNKRHVDFVFAPTPAEVYPQGTEGQTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDVACFGEKDFQQLALIRKMVADMGYDIEIIGVPIVRAKDGLALSSRNGYLTADQRKIAPGLYKVLSAVAEKLAAGDRQLDEIIAIAEQELNEKGFRADDIQIRDADTLLELTDASQRAVILMAAWLGQARLIDNQIVTLGQ
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRC_ENTFA
Sequence: MKTLIKNGKIIKKENQLIEAALWLENGVIHAIGESFDEADFEQVFDANGQLITPGLVDVHVHFREPGFTYKETIKTGSKAAARGGFTTVCAMPNLNPVPDTAEKLSEVYDLIQKDAVVKVLQYAPITEELRSEVLTNQKALKEAGAFAFTNDGVGVQTAGTMYLAMKEAAALNMALVAHTEDESLLFGGVMHEGEVSKKLGLPGILSATEASQIARDITLAKETGVHYHVCHVSTEESVRVIRDAKKAGIHVTAEVSPHHLILVDEDIPGDEGFWKMNPPLRGLADRQALIDGLLDGTIDCIATDHAPHGLEEKQQSFLNAPFGIVGSETAFQLIYTNFVETGIFTLEQVIDWMAVKPAEIFGLNAGTLTIGAPADIAVFDLATAAPIDAEAFESMAVNTPFTGWTVKGKTLMTFVDGALAWSEEAQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: RS15_KARMG
Sequence: MYLNSNKKKLIIKNYGLSEYDTGNCIVQIALLTFKIKNITNHLKYNKKDFNTERSLQILVSKRKKLLKYIEKKNNTQL
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SECE_STAAS
Sequence: MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFFYALDLGITALKNLLFG
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PDUL_CITK8
Sequence: MDKQLLETTVSKVLDEMRERPIPLGVSNRHIHLSAEDYARLFPGQPISEKKALLQPGQYAADQTVTLIGPKGQLKNVRLLGPLRRTSQVEISRTDARTLGIAAPLRMSGDLKGTPGIRLVSPFAELDLASGVIVAQRHIHMSPLDALIFRVAHGDKVSVAIEGNARRLIFDNVAIRVSADMRLEMHIDTDEANAAGADSPDAFATLVTPR
What is the function of this protein?
Involved in 1,2-propanediol (1,2-PD) utilization within the bacterial microcompartment (BMC) dedicated to 1,2-PD degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.
What are the official names of this protein?
Phosphate propanoyltransferase, Phosphate acyltransferase PduL, Phosphotransacylase PduL, PTAC, Propanediol utilization protein PduL.
What is the protein family that this protein belongs to?
Belongs to the PduL family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: DEOC_STRGC
Sequence: MKLNKYIDHTLLKPEATKEQIEKVIEEAKEYDFASVCVNPTWVKLAAEGLSGSDVKVCTVIGFPLGATTPEVKAFETKNAIENGADEIDMVINIGALKSGNLDLLERDIQAVVEASGEKLVKVIIETCLLTDQEKVLACQVSQKAGADFVKTSTGFSTGGATVEDVALMRQTVGPDMGVKASGGARSYDDAQAFIKAGATRIGASSGVAIMKGETASGNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCAN2_BOVIN
Sequence: MPAPSMDCDVSTLVACVVDVEVFTNQEVKEKFEGLFRTYDDCVTFQLFKSFRRVRINFSNPKSAARARIELHETQFRGKKLKLYFAQVQTPETDGDKLHLAPPQPAKQFLISPPASPPVGWQPISDATPVLNYDLLYAVAKLGPGEKYELHAGTESTPSVVVHVCDSDIEEEEDPKTSPKPKIIQTRRPGPPPSVSN
What is the function of this protein?
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A.  Could play a role during central nervous system development (By similarity).
What are the official names of this protein?
Calcipressin-2, Down syndrome candidate region 1-like 1, Regulator of calcineurin 2.
What is the protein family that this protein belongs to?
Belongs to the RCAN family.
Protein: NEC1_RAT
Sequence: MKQRGWTLQCTAFTLFCVWCALNSVKAKRQFVNEWAAEIHGGPEAASAIAEELGYDLLGQIGSLENHYLFKHKNHPRRSRRSALHITKRLSDDDRVIWAEQQYEKERRKRSVPRDSALNLFNDPMWNQQWYLQDTRMTASLPKLDLHVIPVWQKGITGKGVVITVLDDGLEWNHTDIYANYDPEASYDFNDNDHDPFPRYDPTNENKHGTRCAGEIAMQANNHKCGVGVAYNSKVGGIRMLDGIVTDAIEASSIGFNPGHVDIYSASWGPNDDGKTVEGPGRLAQKAFEYGVKQGRQGKGSIFVWASGNGGRQGDNCDCDGYTDSIYTISISSASQQGLSPWYAEKCSSTLATSYSSGDYTDQRITSADLHNDCTETHTGTSASAPLAAGIFALALEANPNLTWRDMQHLVVWTSEYDPLANNPGWKKNGAGLMVNSRFGFGLLNAKALVDLADPRTWRNVPEKKECIIKDNNFEPRALKANGEVIVEIPTRACEGQENAINSLEHVQFEATIEYSRRGDLHVTLTSAAGTSTVLLAERERDTSPNGFKNWDFMSVHTWGENPVGTWTLKVTDMSGRMQNEGRIVNWKLILHGTSSQPEHMKQPRVYTSYNTVQNDRRGVEKMVNVVEEKPTQNSLNGNLLVPKNSSSSSVEDRRDEQVQGAPSKAMLRLLQSAFSKNTPSKQSSKIPSAKLSVPYEGLYEALEKLNKPSQLEDSEDSLYSDYVDVFYNTKPYKHRDDRLLQALMDILNEKN
What is the function of this protein?
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues.  Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
What are the official names of this protein?
Neuroendocrine convertase 1, NEC 1, Prohormone convertase 1, Proprotein convertase 1, PC1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules.
Protein: SYP_HAEIE
Sequence: MRTSQYLFSTLKETPNDAQVVSHQLMLRAGMIRPMASGLYNWLPTGIRVLKKVEKIIREEMNKGGAIEVLMPVVQPAELWEESGRWEQYGPELLRFEDRGNRNFVLGPTHEEVITDLIRREVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRSREFIMKDAYSFHTTQESLQETYDVMYQVYSNIFNRLGLDFRAVQADTGSIGGSASHEFQVLASSGEDDVVFSTESDFAANIELAEAVAIGERQAPTAEMTLVDTPNAKTINELVEQFNLPIEKTVKTLIVKGADENQPLVALIIRGDHELNEIKAQKHPLVADPLEFADEAEIKAKIGARVGSLGAVNLNIPAIIDRTVALMSDFSCGANIDGKHYFNVNWERDVAMPEVFDLRNVVEGDRSPDGKGTLQIKRGIEVGHIFQLGKKYSEAMKATVQGEDGKPLVMTMGCYGIGVTRVVASAIEQHHDDRGIIWPSDEIAPFTVAIVPMNMHKSESVQKYAEELYRTLQSQGVDVIFDDRKERPGVMFADMELIGVPHMVVIGEKNLDNGEIEYKNRRSGEKEMISKDKLLSVLNEKLGNL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCF4_SOLLC
Sequence: MTWRSDDIWIELITGSRKISNFCWALILFLGSLGFLLVGTSSYLGRNLLSFFPPQQIIFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGKNRRIFLRFLIKDIQSVRIEVKEGIYARRVLYMDIRGQGSIPLTRTDENLTPREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.