PharMolix/UniProtQA huggingface dataset:
Protein: SCC4_XENTR
Sequence: MAATAVVAPQAEASESWYLALLGFAEHFRTSSPPKIRLCVHCLQAVFQFKPSQRIEARTHLQLGSVLYHHTKNSELARQHLEKAWLISQQIPQFEDVKFEAASLLSELYCQENSVDAAKPLLRKAIQISQQTPYWHCRLLFQLAQLHTLEKDLVSACDLLGVGAEYARVVGSEYTRALFLLSKGMLLLMERKLQEVHPLLTLCGQIVENWQGNPIQKESLRVFFLVLQVTHYLDAGQVKSVKPCLKQLQQCIQTISTLHDDEILPSNPADLFHWLPKEHMCVLVYLVTVMHSMQAGYLEKAQKYTDKALMQLEKLKMLDSSPILSSFQVILLEHIIMCRLVTGHKATALQEISQVCQLCQQSPRLFSNHAAQLHTLLGLYCISVNCMDNAEAQFTTALRLTTHQELWTFIVTNLASVYIREGNRHQELYSLLERINPDHNFPVSSHCLRAAAFYIRGLFSFFQGRYNEAKRFLRETLKMSNAEDLNRLTACSLVLLGHIFYVLGNHRESNNMVVPAMQLASKIPDMSVQLWSSALLRDLNKACGNNIDAHEAAQMHQNFSQQLLQDHIEACSLPEHNLITWTDGSPPVQFQAQNGPTTSLASLL
What is the function of this protein?
Plays an important role in the loading of the cohesin complex on to DNA.  Plays a role in sister chromatid cohesion and normal progression through prometaphase.
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, MAU-2, Cohesin loading complex subunit SCC4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Binds to chromatin from the end of mitosis until prophase.
Protein: ADRB1_RAT
Sequence: MGAGALALGASEPCNLSSAAPLPDGAATAARLLVLASPPASLLPPASEGSAPLSQQWTAGMGLLLALIVLLIVVGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITLPFRYQSLLTRARARALVCTVWAISALVSFLPILMHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLTGPPRPPSPAPSPSPGPPRPADSLANGRSSKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACRRRAAHGDRPRASGCLARAGPPPSPGAPSDDDDDDAGATPPARLLEPWAGCNGGTTTVDSDSSLDEPGRQGFSSESKV
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  This receptor binds epinephrine and norepinephrine with approximately equal affinity.  Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity).  Involved in the regulation of sleep/wake behaviors (By similarity).
What are the official names of this protein?
Beta-1 adrenergic receptor, Beta-1 adrenoreceptor, Beta-1 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity). Colocalizes with RAPGEF2 at the plasma membrane.
Protein: GUAA_STRT2
Sequence: MQKERVIMTNISTLNDVQKIIVLDYGSQYNQLIARRIREFGVFSELKSHKITADEVRAINPIGIILSGGPNSVYAEDAFGIDEEIFELGIPILGICYGMQLLTHKLGGKVVPAGEAGNREYGQSTLRLRAQSELFAGTPEEQVVLMSHGDAVTEIPEGFHLVADSVDCPFAAMEDTKKNFYGIQFHPEVRHTVYGNDILKNFAFSICGAKGDWSMANFVDMQIAQIRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKGEGDQVMEMLGGKFGLNIIRVDASKRFLDLLAGVDDPEKKRKIIGNEFVHVFDDEASKLKGVDFLAQGTLYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGMPDEVVWRQPFPGPGLAIRIMGEITEEKLETVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSIDGMTADFAKLPWEVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NHAB_TERTT
Sequence: MSSNLPAAFANNFLGQSSTWYKTTILAFLVINPVVYAIDPFIAGWVLILEFIFTLAMALKCYPLQPGGLLAIEAVILGMTSPESVFHETEANFEVILLLIFMVAGIYFMKDLLLYVFTKILLGIRSKIVLSLLFSLVAAVLSAFLDALTVTAVLIAVAVGFYAVYHQFASGGGLSSNQYDHTDDSKVDSSNREDLEGFRSFLRSLIMHGAVGTALGGVCTLVGEPQNLLIAQQADWNFVEFFLQVAPVSMPTLIGGLVTCIAVEKLGIFGYGAQLPDKVRTILMDFDKQETSKRTNRDIAALVVQALAGVVLMVSLALHLAEVGLIGLLVIILLTSFNGITEEHRIGHAFEEALPFTALLVVFFAVVAVIHDQHLFEPITHMLLHMDESVQGPMFFIANGLLSMISDNVFVATVYITEVKNALVAGDISREHFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVLMALPYTIVLSVIGYIAVYQLAAG
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CBPA_ECOHS
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLNVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CCZ1_KLULA
Sequence: MSVQFIVLFRDDDDNKDDSCKLLLYHDLTAHMLSTNEKEQKIGIIKGMWRFSNEFSQSNDYCHVELDSYSMLVLEVEPSYYLALGFENTHNSQWPKYKVRLSQCYQFFAMQHGKMQDIEDKTLSGLLNEHFIPFWDEINLIPDYFLMQDINTAIDDKMFPCCQFADALNSISEVKDWQNYLKNNVLLSEENYLNIKDVCVYHLPKNNKNTKEYGFITNFDPQFKSLPTLSNWLVGIDSMYGTVSSHGLAGTMSLTETEQQIELDAEEAHHEQPPNIKTVWDNVTLPITFTMDALKDIGQLTGVSNSLSLFTNMKPSWNLWSSSSENGAGSAKLDDKDEYSWLISPLNPSFLPKVYQMRKFYLQFDDWSQYNILFWKFKDVIVAVIVDPSFKKISEESFLMKLQEELWNGISLFYENTGFEKRQCSFDYTILFKEEGKYYSSIPRWKNGLDESDTALKLVIKGLDETLQFLTNNANRKSSVATVTEVGHDMSLTDHPIPSDPSKGEDGTEKTDKSESSIFSKLNESQLVELNKELMVILGTRSLTVWYKDANTKERMLKLNNGLMVYLLENNRKLVLIIKNWFIDSQQKTKSKRSTDMIESLGKDVSTWWNRIKDHEPL
What is the function of this protein?
In complex with MON1, is required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.  The CCZ1-MON1 complex acts at the fusion of vesicles with the vacuole, through its regulation of the SNARE complex during the coordinated priming and docking stages of fusion, and particularly at the stage of tethering/docking.
What are the official names of this protein?
Vacuolar fusion protein CCZ1.
What is the protein family that this protein belongs to?
Belongs to the CCZ1 family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein.
Protein: XDH_PAENI
Sequence: MTKTAIVRVAMNGITGRMGYRQHLLRSILPIRDAGGFTLEDGTKVQIEPILVGRNEAKIRELAEKHKVAEWSTDLDSVVNDPTVDIIFDASMTSLRAATLKKAMLAGKHIFTEKPTAETLEEAIELARIGKQAGVTAGVVHDKLYLPGLVKLRRLVDEGFFGRILSIRGEFGYWVFEGDVQAAQRPSWNYRKEDGGGMTTDMFCHWNYVLEGIIGKVKSVNAKTATHIPTRWDEAGKEYKATADDASYGIFELETPGGDDVIGQINSSWAVRVYRDELVEFQVDGTHGSAVAGLNKCVAQQRAHTPKPVWNPDLPVTESFRDQWQEVPANAELDNGFKLQWEEFLRDVVAGREHRFGLLSAARGVQLAELGLQSNDERRTIDIPEITL
What is the function of this protein?
Catalyzes the NADP(+)-dependent oxidation of D-xylose.  Is able to use both NADP(+) and NAD(+); however, the enzyme shows a very strong preference for NADP(+).  Is likely involved in the first step of the oxidative D-xylose degradation pathway.
What are the official names of this protein?
D-xylose dehydrogenase, NADP-dependent D-xylose dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: HIS2_METM6
Sequence: MNVLKEVYSTIEKRIQEKPEGSYVAKLTTDDKKTAVNKICEKVGEEAAEVILAAKDNDKAEIIYESADLIFHTMVLLAKSGITYEELSEEFKKRMK
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_FUSNN
Sequence: MKFLGIIPARYSSTRLEGKPLKMIEGHTMIEWVYKRAKKSNLDSLIVATDDERIYNEVINFGGQAIMTSKNHTNGTSRIAEVCEKMTEYDTIINIQGDEPLIEYEMINSLIETFKENKDLKMATLKHKLLNKEEIKNPNNVKVVCDKNDYAIYFSRSVIPYPRKNGNISYFKHIGIYGYKRDFVIEYSKMLATPLEEIESLEQLRVLENGYKIKVLETTHSLIGVDTQENLEQVINYIKENNIKI
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPO13_SACSH
Sequence: MVSGMSTEEEKEGTNDEEVSEEREVEETSEEEFPKLSIQDIELLMKNTEIWDNLLNGKISVDEAKRLFEDNYKDYEKRDSRRKAKKAASKKVKKTKKKEKSVEG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (Probable).  A molten-globule protein, it binds dsDNA in the RNAP, in vitro binds dsDNA but not ssDNA (Probable) (PubMed:22848102).  Its position in RNAP implies it functions in both transcription initiation and elongation (Probable).
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo13.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo13 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUPC_BACSU
Sequence: MKYLIGIIGLIVFLGLAWIASSGKKRIKIRPIVVMLILQFILGYILLNTGIGNFLVGGFAKGFGYLLEYAAEGINFVFGGLVNADQTTFFMNVLLPIVFISALIGILQKWKVLPFIIRYIGLALSKVNGMGRLESYNAVASAILGQSEVFISLKKELGLLNQQRLYTLCASAMSTVSMSIVGAYMTMLKPEYVVTALVLNLFGGFIIASIINPYEVAKEEDMLRVEEEEKQSFFEVLGEYILDGFKVAVVVAAMLIGFVAIIALINGIFNAVFGISFQGILGYVFAPFAFLVGIPWNEAVNAGSIMATKMVSNEFVAMTSLTQNGFHFSGRTTAIVSVFLVSFANFSSIGIIAGAVKGLNEKQGNVVARFGLKLLYGATLVSFLSAAIVGLIY
What is the function of this protein?
Transport of the pyrimidine nucleoside uridine.
What are the official names of this protein?
Nucleoside permease NupC.
What is the protein family that this protein belongs to?
Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTTG3_PANTR
Sequence: MATLIYVDKENEEPGTLVATTDGLKLGSGPSIKALDGRSQVSISCFGKTFDAPTSLPKATRKALGTVNRATEKSVKTNGPLKQKQPSFSAKKMTEKTVKAKNSVPASDDAYPEIEKLFPFNPLGFESFDLPEEHQIAHLPLSGVPLMILDEERELEKLFQLGPPSPLKMPSPPWKSNLLQSPLSILLTLDVELPPVCSDIDI
What are the official names of this protein?
Putative pituitary tumor-transforming gene 3 protein, Securin-3, rcPTTG1.
What is the protein family that this protein belongs to?
Belongs to the securin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GIAG_GIAIN
Sequence: MKSSFSTVSSYSDHKFAVKDAPTTIRDSLRLTNAVEDPGYMTLSLISENKVDDLMFNSKMFQDHMVNDFRPKFSHADSSEIMITLNNLKNDILSTKNIRELESTDLRSEVAKQFAARRAELVSHLNASLRPLIDEVFSMEQRLKAFDAENADFVGKTKQYKSTFRSEVHSRIRAGQSKLDALRHGLQTEINSLEAIIEREFAQAANRLNQEVSNFKESFDASERNIKLQKKHVISGMNEKIKSFAESVAKYLPILKKNSEERRFNQMMMQKNLAEIMTVLSDNSEHFGDYCFSDLVPDTRIFDAIMTTKVD
What is the function of this protein?
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst.  They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk.
What are the official names of this protein?
Giardin subunit gamma.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Microribbons of ventral disc.
Protein: PKHJ1_BOVIN
Sequence: MRYNDKELQALSRQPAEMAAELGMRGPKKGSVVKRRLVKLVVNFLFYFRTDEAEPIGALLLEHCRVIHEEPNSFSISFLEDPERKYHFECCSEEQCQQWMAALRQASYEFMRRSLIFYRNEIQKMTGKDPLEQYGISEEARFQLSGLKA
What are the official names of this protein?
Pleckstrin homology domain-containing family J member 1, PH domain-containing family J member 1.
Protein: UGE4_ORYSJ
Sequence: MAGGEVVAVAAAAAGTSRTVLVTGGAGYIGSHTVLQLLAAGFRVVVADSLGNSSELAVRRVAALAGDKARNLSLHKVDIRDKGGLEKVFSSTRFDAVVHFAGLKAVGESVQKPLLYYDHNVAGTIILLEVMAAHGCKKLVFSSSAAVYGSPKNSPCTEEFPLTPHNPYGRTKLIAEEICRDIYHSDSEWSIILLRYFNPVGAHPSGYLGEDPCGIPNNLMPFVQQVAVGRRPSLTIFGNDYATKDGTGVRDYIHVVDLAEGHIAALRKLFESSIGCQAYNLGTGKGTSVLEIVNAFEKVSGKKIPLVIGPRRPGDAEILFSSAAKAEREFKWKAKYGIEEMCRDQWNWASKNPFGYASPDSTKQNGHSH
What is the function of this protein?
Catalyzes the interconversion between UDP-glucose and UDP-galactose.
What are the official names of this protein?
UDP-glucose 4-epimerase 4, OsUGE-4, UDP-galactose 4-epimerase 4.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: PHO1A_ARATH
Sequence: MKFGKIFKKQMVPEWVEAYVDYNGLKRVLKEIRSYKHSKLTRAASRVSQQAEALHRSFSGLSFHPRHSERAGDIEDQVIKVDTVQEEGSRKLYETKFLKKSEEGGEFEESFFKKLDENLNKVNKFYRDKVKEVIEEAALLDKQMDALIALRVKMQKPDVDNLNLEKHPSDKVVVDTSDNTMRTQGTANTDMVHGIERTNIPEEEASHIMADIVPVSHTNGDEEEASIGDKQDLREILERVKMNDVLESPITTLKGVFGDSNEPISKKGLKKGEEQLRLVFSEFYQKLRRLKEYSFMNLLAFSKIMKKYEKIASRNASRNYMKIVDNSLIGSSDEVNRLLERVEVTFVKHFSSGNRREGMKCLRPKVKRERHRVTFFSGFFSGCSIALVIAVVFKIESRKIMEKNYGTEYMANIIPLYSLFGFIILHMLMYSANIYFWKRYRVNYTFIFGFKQGTELGDREVFLVSTGLAVLAFVCFLLNLQLDMDWRMKHHKTLPEVIPLCLATIVLFILFCPFNIIYRSSRFFFIRSLFHCICAPLYEVTLPDFFLGDHLTSQIQAIRSFELFICYYGLGEYLQRQNKCHSHGVYNAFYFVVAVIPYWLRFLQCIRRLCEEKESVHGYNALKYMLTIIAVIVRTAYELKKGRTWMILALVSSGVATGMNTFWDIVIDWGLLRKHSKNPYLRDKLLVPHKSVYFAAMVVNVILRVAWMQLVLEFNLKSLHKIAVTSIISCLEIIRRGIWSFFRLENEHLNNVGKYRAFKSVPHPFHYYDDDDVDKDD
What is the function of this protein?
May transport inorganic phosphate (Pi).
What are the official names of this protein?
Phosphate transporter PHO1 homolog 10, Protein PHO1 homolog 10, AtPHO1;H10.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS6_STRTD
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWEKRRLAYEIQDFREGIYHVVNVEANDATALNEFDRLSKINGDILRHMIVKLDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: END4_PECAS
Sequence: MKYIGAHVSAAGGVDQAVIRAHEIKATAFALFTKNQRQWQAAPLSTEVIDRFKAACEQYAYMSAQILPHDSYLINLGHPDGEALEKSRIAFIDEMSRCQLLGLSLLNFHPGSHLKQIEEADCLARIAESINIALAETDGVTAVIENTAGQGSNLGFRFEHLAAIIDGVEDKSRVGVCIDTCHAFAGGYDLRTEADCEATFAEFDRIVGFRYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGKTAFSYIMKDTRFDGIPMILETVNPDIWADEIAWLKSEAQY
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: TKTL1_MOUSE
Sequence: MSEAEASSGMAHNAGPDEKTLQVLRDMANRLRIRSIKATNSSTTSYLIPCSNAEIMSVLFFYTMRYKQEDPENPDNDRCILSKGLPFVNVATGWPGQGLGAACGMAYTGKYFDQASYRVFCLLGDEESTEGSVWEAFAFASYYNLDNLMAIFDVNRIGHSSSMSVEHCIAIYQKRCEAFGWNTYVVDGRDVKTLCHVFSQAAQVRGKPTAVVAKTFKARGMPNVEDAESWYGRPMPKERADAIVKLIESQIQTNKILVPSPPIEDSPQINIMNICMTSPPVYVADDKVSTQRACGLALAKLGHENDRVIVLGSDTKNCNFSDIFKKEHPERFIQCCIAEQNMVNVALGCSTRDRTIVFAYSFAAFFTRAFDQIRLGAISQININLIGCHCGVSTGDDNPYHMALEDLAMFRAIPNCVVFYPSDAVSTEHAVYLAANTKEMCFIRTSQAETAIIYTTQETFQIGQAKVVRHSDNDKVIVIGAGVTLHEALVAAAELSKEDISIRVIDLFTIKPLDIATIISNAKATGGRIITVEDHYPEGGIGGAVCAAVSMEPNIVVHNLAVMDVPRSGRCNEALDFSGISSRHIIVAVKCILMT
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase-like protein 1, Transketolase 2, TK 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic and to a lesser extent also nuclear.
Protein: PUR9_ALIFM
Sequence: MNNARPIRRALISVSDKTGIVEFAQALAERGVDILSTGGTARLLAEKGISVTEVSDYTGFPEMMDGRVKTLHPKVHGGVLGRRGQDDGIMEQHGINPIDMVVVNLYPFAETVAKEGCTLADAVENIDIGGPTMVRSAAKNHKDVTIVVNAHDYDRVITEMDANEKSLTLETRFDLAIAAFEHTASYDGMIANYFGTMVPSYGENKEGDEESKFPRTFNQQFEKKQDMRYGENSHQAAAFYVEANPEEASVSTARQIQGKALSYNNIADTDAALECVKEFDEPACVIVKHANPCGVALGKNILEAYDRAFKTDPTSAFGGIIAFNRELDAATATAITERQFVEVIIAPSVSAEAVEIVAAKKNLRLLECGEWTTKTTGFDVKRVNGGLLVQDRDQGMVSEDDLQVVSKRQPTAEELKDALFCWKVAKYVKSNAIVYSKGDMTIGVGAGQMSRVYSAKIAGIKAADEGLQVEGCVMASDAFFPFRDGIDAAAEAGIKCVIQPGGSMRDNEVIEAADEHGMAMIFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: TMN2_ARATH
Sequence: MRTPTTILLLVGAILFSGAGYVRSDASDHRYKEGDTVPLYANKVGPFHNPSETYRYFDLPFCIPEGVKEKKEALGEVLNGDRLVSAPYKLNFRDEKESEVYCNKKLSKEEVKQFRKAVEKDYYFQMYYDDLPIWGFIGKVDKDIKSDPSEFKYFLYKHIQFEILYNKDRVIEISARMDPHSLVDLTEDKEVDAEFMYTVKWKETETPFEKRMEKYSMSSSLPHHLEIHWFSIINSCVTVLLLTGFLATILMRVLKNDFMKYAQDEEAADDQEETGWKYIHGDVFRFPTHNSLFAASLGSGTQLFTLTIFIFMLALVGVFYPYNRGALFTALVVIYALTSGIAGYTSASFYCQLEGKSWVRNLLLTGCLFCGPLFLTFCFLNTVAITYTATAALPFGTIVVIVLIWTLVTSPLLVLGGIAGKNSKAEFQAPCRTTKYPREIPPLPWYRSAIPQMAMAGFLPFSAIYIELYYIFASVWGHRIYTIYSILFIVFIILIIVTAFITVALTYFQLAAEDHQWWWRSFLCGGSTGLFIYAYCLYYYYARSDMSGFMQTSFFFGYMACICYGFFLMLGTVGFRAALLFVRHIYRSIKCE
What are the official names of this protein?
Transmembrane 9 superfamily member 2, Endomembrane protein 8, Transmembrane nine protein 2, AtTMN2.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TWMA_TALWO
Sequence: MASGKAGGASALFSEATQAEQLDSHTYRVNLNQGFCIGAVPNGGYTSACMLAAASKHLGPRGQPDTLTAHFEYPNRTSTGPAIVVIEDVKLGRQISTLHLTLWQGGLLSQAPWIDRSVSRRIVLAYTTHTNLRTFSGISMPTGYEVTPAAELPSVSDFEALKTHGADDAWAESKLPKGWAAMMLSLTQWRFYVPRKEPLSPGVLDMWIRLASGEKITQGALAYVVDSFPHNMHTFLAAPALRELLNASPERSGDSEVKDVRKKDQQRAEMWFPTVVMNIEAKTALPEEGVEWLSVRVSSKQIKEGKFDLEVLVRDTDGEMVALSNHVAMILSVERNTGKKSGSSKASL
What is the function of this protein?
Thioesterase-like protein; part of the gene cluster that mediates the biosynthesis of wortmanamides A and B, reduced long-chain polyketides amidated with a specific omega-amino acid, 5-aminopentanoic acid (5PA) (PubMed:29343058).  The PKS modules of TwmB are involved in the synthesis of the polyketide backbone, whereas the non-canonical C domain of TwmB is a bonafide condensation domain that specifically selects 5PA and catalyzes amidation to release polyketide chain (PubMed:29343058).  The C domain clearly prefers C16 and C18 fatty acyl substrates, which is consistent with simultaneous formation of both octaketide and nonaketide acyl amides wortmanamides A and B (PubMed:29343058).  Because TwmB lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase TwmE (PubMed:29343058).  The roles of the remaining enzymes have still to be clarified (Probable).
What are the official names of this protein?
Thioesterase-like protein TwmA, Wortmanamides biosynthesis cluster protein A.
Protein: RL20_BLOFL
Sequence: MVRVKNSVTAHSRHKKILKRATGYYGARSRTYRVAYQAIIKAGQYAYRDRKQKKRIFRQLWISHINAVARQYGLSYNNLINNLYKSSIYINRKMLAELATSDQVAFLNLVNNIKIHSK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: Y6K4_BPP22
Sequence: MAKKPGENTGKNGGIYQEVGPRGGKKDNFATVKDNERLPPTTKPGNGWVLDKRTPDSKK
What are the official names of this protein?
Uncharacterized 6.4 kDa protein in sieA-mnt intergenic region, ORF59A.
Protein: HLDE_NITSB
Sequence: MKPRILVLGDVMIDHYLFGKCDRISPEAPVQVVDVQKEELVLGGAGNVVNNLLAFGAEVGIISVVGEDANGIWLEQRFQEKGVQTYLLKENRPTTKKSRIIASNQQIVRVDREEKKEIESLTQQKILNVFDRVIKEYDLVLLSDYDKGVLTKEVTQTVIQRSSVPVFVDPKNDFEKYRGATLIKPNKKEASKAVGFLIKNEEDLKRAGWKLKKELDLQSLIVTLSEEGMAIFEEEMMRIPTVAKEVYDVTGAGDTVLAALGYAVAKGKNLKEAAVFANLAAGVVVGKVGAATATLEEIEEYERSIRKAPTEEFIKDFEEIELISKDLHKRGKRIVFTNGCFDILHLGHVKYLQKAKELGDVLIVGVNSDASVKRLKGDDRPINPQFDRAYLLASLEAVDYVVIFEEDTPYELIKIVKPDILVKGGDYKGKEVVGSDIAKEVRLIDFVEGKSTTAIVERMRSC
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: CCAR1_XENLA
Sequence: MAQFGGQKNPPPWATQFTATAVSQPGPLAVQQSSLLGASPTIYTQQSALAAAGLASPSPANYQLSQTAALQQQAAAAAAAAAAALQQQYTQPQQTIYSVQQQLQPPPQAILTQPAVALPTSLALSTPQQAAQITVSYPTPRSNQQQTQPQKQRVFTGVVTKLHETFGFVDEDVFFQLTAVKGKSPQAGDRVLVEATYNPNMPFKWNAQRIQTLPNQNPASAQSLIKNPAAVMQPVAQPTAYAVQTQPPPQAQTLLQAQISAATLTPLLQTQTSPLLQQPQQKAGLLQTPVRIVSQPQPVRRIEPPSRFSVRNDRGDSILSRKDDRNRERERERRRSRDRSPQRKRSRERSPRRERERSPRRPRRVVPRYTVQISKFCLDCPGCDTMELRRRYQNLYIPSDFFDAQFTWVDAFPISRPFQLGNYSNFYIMHKEVDPLEKNTAIVDPPDADHTYSAKVMLLASPSLEELYHKSCALAEDPIEVREGFQHPARLIKFLVGMKGKDEAMAIGGHWSPSLDGPNPDKDPSVLIRTAVRCCKALTGIELSLCTQWYRFAEIRYHRPEETHKGRTVPAHVETVVLFFPDVWHCLPTRSEWENLCHGYKQQLVDKLQGDRKEADGEQEEEDKEDGDAKEISTPTHWSKLDPKIMKVNDLRKELESRTLSSKGLKSQLIARLTKQLRIEEQKEEQKELEKCEKEEEEEEERKSEDDKEEEERKRQEELERQRREKRYMLPDEPAIIVHPNWSAKNGKFDCSIMSLSVLLDYRIEDNKEHSFEVSLFAELFNEMLQRDFGVRIYRELLALPEKEEKKDKEKKCKKEDKRERKEDKDDDDEPKPKRRKSSDDKIKLEEKEERKRDDRRKEDYREEDDPDYENQDDYEPIAAEEDDGDYDDREDDDDDSSSKDKREDKRDGNRYSKERQSKDKEKDKKQMVTVNRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRAQVKKLFTKILLKESLLYRKLTDTATEDGSHEETDPLHNDILGNCSLLPSKAVRTGLSTVEDKGGLIVYKGAMVDVGSLLQKLEKSEKTRTELEHRLQTLESKTEEDEKTISQLEASNRNLSEELKQTKDDVGHLKDSLKAAEDTRSLYEDQLTNTIKNLSAAMGEIQVVLNKNPSTTEDQKSKENGSS
What is the function of this protein?
Transcriptional coactivator for nuclear receptors which may play an important role in regulating cell growth and apoptosis.
What are the official names of this protein?
Cell division cycle and apoptosis regulator protein 1.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: Y1687_STRP1
Sequence: MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSVRHHIEGIKLVDEEGNDVTPEKLRQVQREKGLHGRSLDDPKS
What are the official names of this protein?
UPF0291 protein SPy_1687/M5005_Spy1383.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KADA_METVS
Sequence: MKNNVVVVTGVPGVGSTTVMQKAMDKLIEEKISYKMVNFGSMMFEVAKEEGLAEERDQMRKLNPETQKRIQKMAGRKIAELSKHSPVAVDTHSTVKTPKGYLPGLPAWVLNELNPDMVIVVETDGDEILMRRMGDESRNRDLETTKSIEEHQFMNRCAAMAYGVLTGATVKIVKNKNGLVDNAVEELISVLR
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_SALPC
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.