PharMolix/UniProtQA huggingface dataset:
Protein: HISX_CARHZ
Sequence: MKLILNKEELLDKYSRRKAVEEDIEQQVRKILNEVASSGDEALIEYAREFDGFKGDLSNLKVSEEEIDKAYREVDDGFLNSLRKAIQRVFDFHQKQLPRSWFTTEENGNILGQIYTPVEVAGIYVPGGTAAYPSSVVMNAVPAKVAGVKRIVMVSPQKGERMNPYVLVAAREAGVTEIYRVGGAHAIAALAFGTKTIPRVDVITGPGNIYVTIAKKLVYGTVNIDMLAGPSEVVVIADSSAKPEYLAADMLSQAEHDSLASGVVITWDGELARKTAQKVEEYLKLLPRREIILKALENCGGIVVVDDEEEALQLANQLAPEHLELMLPNPFGYLAKVKNAGAVFLGQFSPEPMGDYLAGPNHVLPTSGTSRFYSPLSVDNFLKKSSVIYYSQEGFLADARDVIKLAETEGLFAHALSVKVRISNE
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: GLMU_DESHY
Sequence: MPHWAAVIMAAGKGTRMKSKLPKVMHTLAGKPMLQHVLDCVRSVEIPRSMVVLGHGREQIEATLDDRTEVVVQEEQCGTGHAIMQAIPHCHEVDHIIVLSGDQPLIRPETLRNLIRIHIEHNAAATLLTACFENPHGLGRILKEGDQFLRVVEEKDATPEERLVQEINTGTYCFNVAKLREALKNITPKNAQGEYYLTDVFAVFHAQGEVIRTYCTEDVHEALGINSRAQLAAAEDVARQRILSYWMEEGVTIIDPRSTFIEAGVVLQPDVVLQPFTILKGRTQVAEDAVIGPHTTLTDCTVGAGSEVSHTVGNQAVIGGHCTIGPYAYLRPGTVLQDKVKVGDFVEIKNSQIGEGSKIPHLSYVGDSQVGKSVNIGAGTITCNYDGVNKYKTIIRDKAFLGSNTNLVAPVEIGEGSVTGAGSTISKNVPANTLAIERSTQKHIENWVRNKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT35_HUMAN
Sequence: MAAAALPAWLSLQSRARTLRAFSTAVYSATPVPTPSLPERTPGNERPPRRKALPPRTEKMAVDQDWPSVYPVAAPFKPSAVPLPVRMGYPVKKGVPMAKEGNLELLKIPNFLHLTPVAIKKHCEALKDFCTEWPAALDSDEKCEKHFPIEIDSTDYVSSGPSVRNPRARVVVLRVKLSSLNLDDHAKKKLIKLVGERYCKTTDVLTIKTDRCPLRRQNYDYAVYLLTVLYHESWNTEEWEKSKTEADMEEYIWENSSSERNILETLLQMKAAEKNMEINKEELLGTKEIEEYKKSVVSLKNEEENENSISQYKESVKRLLNVT
What are the official names of this protein?
28S ribosomal protein S35, mitochondrial, MRP-S35, S35mt, 28S ribosomal protein S28, mitochondrial, MRP-S28, S28mt, Mitochondrial small ribosomal subunit protein mS35.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS35 family.
Protein: Y236_NITOC
Sequence: MAITDWPVHERPREKLLQRGPNALSDAELLAIFLRTGVAGKTAVDLARELLESFGSLRALLEADLKQFCHAPGLGIAKYTQLQACLEMGRRHLEDTLKRGDVLTDPQTTQRYLVARLRAYPFEVFSCLFLDNRHRVLAFEELFRGTIDGASVHPREVLKRALAHNAAAVILAHNHPSGVAEPSRADECITQRLKEALALVDIRVLDHIIVGDGETLSFAERGLL
What are the official names of this protein?
UPF0758 protein Noc_0236.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: SECE_SULTO
Sequence: MSLSQRLKNLREDWKRIISVAKKPEKDTLNQSIKLTLLVMAIVGIIAYIIQLTVALLLH
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE, Protein transport protein Sec61 gamma subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL23_VIBCM
Sequence: MIREERLLKVLRAPHISEKATMSAEKSNTIVFKVAKDATKKEIKAAVEKLFEVEVKSVNTLIIKGKTKRQGLRQGRRSDVKKAYVTLNEGQDLDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: NUOI_FRATO
Sequence: MRNITNFLKTFLLWELLKGLKVTGKHFFTRKVTVQYPDEKTPISNRFRGLHALRRYENGEERCIACKLCEVVCPALAITINSTEREDGTRRTSSYEMDLFKCIFCGYCEESCPVDSIVETNILEYHFEERGENIMTKAKLLAIGDKYEAQIAADRLQDKDFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL11_BACC2
Sequence: MAKKVIKMVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNARTADQAGLIIPVEITVFEDRSFTFITKTPPAAVLLKKVAGIESGSGEPNRNKVATVKRDKVREIAETKMPDLNAASVEAAMRMVEGTARSMGIVIED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: IF3_TRIV2
Sequence: MPVIEKKRTRDLPQINERIRFPKIRVIDTDGSQLGILTPQEALQLAEEKELDLVLLSDKADPPVCRIMDYGKYKFEQEKKAREARKKQHTADVKEVKMRYKIEEHDYNVRVKQAERFLKDGDKVKATVMFRGREIQHSDLAEDLLKRMATDLEPFGEVQQAPKKEGRNMMMLISPKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_PSEPF
Sequence: MIKDPFARLGLDREVLTVSQLNGRARVLLEDVFSNIWVEGEISNLARPASGHVYFTLKDSGAQVRCALFRQNAARVRQALKDGLAVKVRGKVSLFEGRGDYQLILDTVEPAGDGALRLAFDALKEKLSAEGLFSAERKVPLPAHPQRIGIISSPTGAVIRDIISVFRRRAPQVQLTLIPTAVQGREATAQIVRALKLADARGFDALILARGGGSLEDLWCFNEEAVARAVDACVTPIVSAVGHETDVSISDFVADVRAPTPSAAAELLAPDSSHLIRQVESLHRRLVMRMRDRLMRDRLRLEGMTRRLRHPGERLRQQAQRLDDLDMRMRRAFERQLNTRRERLIRLETRLAGQHPGRQLALLRQRLDSLAERLPRAMNEGLKRRRLQLQSQMQTLHVVSPLATLGRGYSILLDERGNAIRNAAQTHTGQRLKARLGEGELQVRVEDNHLTPVTLSLLD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S1PR1_MOUSE
Sequence: MVSTSIPEVKALRSSVSDYGNYDIIVRHYNYTGKLNIGAEKDHGIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNSSRSFLLISACWVISLILGGLPIMGWNCISSLSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKAKTCDILYKAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIVSCCKCPNGDSAGKFKRPIIPGMEFSRSKSDNSSHPQKDDGDNPETIMSSGNVNSSS
What is the function of this protein?
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G(i) subclass of heteromeric G proteins.  Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases.  Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1.  Required for normal chemotaxis toward sphingosine 1-phosphate.  Required for normal embryonic heart development and normal cardiac morphogenesis.  Plays an important role in the regulation of sprouting angiogenesis and vascular maturation.  Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development.  Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs.  Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis.  Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
What are the official names of this protein?
Sphingosine 1-phosphate receptor 1, S1P receptor 1, S1P1, Endothelial differentiation G-protein coupled receptor 1, Lysophospholipid receptor B1, Sphingosine 1-phosphate receptor Edg-1, S1P receptor Edg-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome. Membrane, caveola. Note=Recruited to caveolin-enriched plasma membrane microdomains in response to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine. Ligand binding leads to receptor internalization (By similarity).
Protein: RPOB_AZOSB
Sequence: MAYSYTEKKRIRKSFAKRAAVLDAPFLLATQIESFASFLQAETPPESRYNQGLQAAFTSIFPISSHSGNARLEFVQYMLGEPAFDVKECQQRGLTFASPLRARVRLVIMDREAPKETIKEVKEQEVYMGEIPLMTTTGSFVINGTERVIVSQLHRSPGVFFEHDRGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDYLYFRVDRRRKMPVTILLRAIGMTPEEILETFHDFDAFHLSAEGAQFELVPDRLRGEVARFDIVDPTGKVIVARDKRITAKHIRELDQAGIKMIGVPDDFVLGRIIARNVVDPETGELLARANEEITEDLLGKLRDAGVRDLVTLYVNDLDRGAYISSTLRIDETADQWAARVAIYRMMRPGEPPTEEAVEALFQGLFYAPERYDLSTVGRMKFNRRAYPEKIDDKAPGWLKRFYDKVGPHGEEGEGVLANEDILAVIGVLVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAVKERLSQAESDNLMPHDLINAKPISAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAVYARTNRHGFLETPYRKVTDGKVTDQIDFLSAIEEGQYVIAQANAEIGGDGALEGDLVSCRHKGEFMLATADQVQYMDVAPGQIVSVAASLIPFLEHDDANRALMGANMQRQAVPCLRPEKPLVGTGIERTVAVDSGTAVQAMRGGVVDYVDAQRVVVRVNDNEALAGEVGVDIYNMIKYTRSNQNTNINQRPVVRVGDLIAKGDVIADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISERVVADDRFTSIHVEELTVVARDTKLGPEEITRDIASLGEAQLSRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMTGTVIDVQVFTREGIERDKRAQSIIDDQLRSFKTDLADQMRIVERDAFARIQRMIVGQKANGGPKKLAKGAAITAEYLETLEFYHWFDIRMADEELAIQLEAVREGLEKTRKDFEQAFEIKKKKLTQGDELPPDVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPYMEDGTPVDIVLNPLGVPSRMNIGQILETHLGWAAKGLGQKIDRLLRANAAAGEVRGLLEEIYNGSGKPEDFSEFTDGDVIELATNLKKGVPFATPVFDGAKEEEIAKMLELAGLPVGGQVTLFDGRTGEAFERKVTVGYKHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVTGRTKVYENIVKGEHKIDSGMPESFNVLVKEIRSLAIDIDLDRE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NHL10_ARATH
Sequence: MAAEQPLNGAFYGPSVPPPAPKGYYRRGHGRGCGCCLLSLFVKVIISLIVILGVAALIFWLIVRPRAIKFHVTDASLTRFDHTSPDNILRYNLALTVPVRNPNKRIGLYYDRIEAHAYYEGKRFSTITLTPFYQGHKNTTVLTPTFQGQNLVIFNAGQSRTLNAERISGVYNIEIKFRLRVRFKLGDLKFRRIKPKVDCDDLRLPLSTSNGTTTTSTVFPIKCDFDF
What is the function of this protein?
May play a role in plant immunity.
What are the official names of this protein?
NDR1/HIN1-like protein 10, AtNHL10, Protein YELLOW-LEAF-SPECIFIC GENE 9.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LIPA_ACTP2
Sequence: MTTATGTKPKKMEAFKMERGVKYRDAAKTSVIQVRNIDPDQELLPKPSWMKIKLPAASAKIDSIKHGMRRHGLHSVCEEASCPNLHECFNHGTATFMIMGAICTRRCPFCDVAHGKPLPLDPEEPRKVAETVQDMKLKYVVITSVDRDDLADRGAAHFAATVREIKALNPECKVEILVPDFRGRVEQAVEILKQNPPDVFNHNLENVPRLYREVRPGADYKWSLELLKIFKQEFPNIPTKSGLMVGLGETNEEILEVMQDLRDHGVTMLTIGQYLQPSRHHLKVERYVPPEEFDMFRSEAERMGFEHAACGPFVRSSYHADLQAKGELVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPA2_NEUCR
Sequence: MAPQQPQPTSQDWDVEFNQVRREKLFRDPPTDRTAYPALQAAVDPHIESFNALFRDDGKPSLLDHALAEIGTKTFLDGDERADPQGKNKLTIRYKSIELQKSQVPPTNRWAKNREIFPAECRERHVSYRGKLSATFEYRINDGEPHEFVRELGQMPIMVKSNKCHLQNNSPAQLVARKEESEELGGYFIVNGIEKLIRMLLVNRRNFPLAIVRPSFQNRGASYTPYGIIMRSVRPDETSQTNVLHYLSDGNVTFRFSWRKNEYLIPVMMIMKALVETNDREIFEGLVGPPQSKGVANTFLTDRVELLLRTYKKYGLYSKTQTRAYLGQKFRVVLGVPDTMSDYEVGTEFLRKIVLVHLGSQDVTEQQDADKFNMLLFMCRKLYALVAGDCAVDNPDAVQNQEILLGGFLYGQIIKERLEELLTVSFRASLRDYLRRNPTVSFQSDTFLKDFPIAIFRRANENIGQSLEYFLSTGNLVSPSGLDLQQVSGFTVVAEKLNFLRFISHFRMVHRGSFFAQLKTTTVRKLLPESWGFLCPVHTPDGSPCGLLNHLAHKCKIMTESVDASTISRLAFELGVVNISSAATSESVVVMLDGRIVGWCTPEECKSIAETLRYWKVNGENGVPLQLEIGYVPPSNGGSYPGLYMSSQPARMVRPVKYLPLQKEDFVGPQEQPYMSIACTEQEVIPGDSTHVEFDPTNILSILANMTPFSDFNQSPRNMYQCQMGKQTMGTPATALAHRTDNKMYRLQTGQTPVVRAPLHNTYGFDNFPNGMNAVVAVISYTGYDMDDAMILNKSAHERGFGHGSIYKTKKVSLKDDSRTRSAKSIVKMFGFAPNSTIRESTRDMLDNDGLPRVGRLLREGDVICAWHTVSADYNGQLVNRDGVTHYERYKDSEDAFVEEVRVIGADNGTEPLQTVSIKLRIPRSPVIGDKFSSRHGQKGVLSQKWPATDMPFSETGIQPDVIINPHAFPSRMTIGMFVESLAGKAGALHGLAQDSTPFKFDEQNTAGDYFGHQLMKAGYNYHGNEPLYSGITGEEFQADIYIGVVYYQRLRHMVNDKYQVRTTGPVVPTTGQPIKGRKKGGGIRVGEMERDALLAHGTSFLLQDRLLNCSDYSKSWMCRQCGSFLSTQPTVSPFIGKRKAVSTVRCRNCAVRLDDMEDVDLMQIDGEIWEDGSGTQWIGGENTTIVAVPGALKYLDVELAAMGIKLKYKVDKKDEIRRGQLVGKKAGDLMLTA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA2, DNA-directed RNA polymerase I polypeptide 2, RNA polymerase I subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: PIGT_HUMAN
Sequence: MAAAMPLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQREGVSHYRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQDTVTDVDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQTLSVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPPTTTYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPPENEAPPVPFLHAQRYVSGYGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSKGKENKPSYIHYQPAQDRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVAAKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLLTRTFHIEEPRTGGLAKRLANLIRRARGVPPL
What is the function of this protein?
Component of the GPI transamidase complex.  Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates.
What are the official names of this protein?
GPI transamidase component PIG-T, Phosphatidylinositol-glycan biosynthesis class T protein.
What is the protein family that this protein belongs to?
Belongs to the PIGT family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RS15_AERPE
Sequence: MNKRREKGQSHSTRPPHPQPPQWLVFTPEEIELLIAELAKKGYGPSMIGIILRDQYGIPLVKPILGKGVSEVLREKGLHPPLPEDLLMLIRKAVNLRRHLDEHPKDYHAKKGLIDLESKIRRLVKYYKRRGVLPPDWKYDPEAAKLLVST
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GLMM_BURPS
Sequence: MGRRYFGTDGIRGKVGDAPITPDFVLRLGYAAGKVLASAPGRAASGARPTVLIGKDTRVSGYMLEAALEAGFSAAGVDVMLAGPMPTPGVAYLTRALRLSAGVVISASHNPYHDNGIKFFSADGNKLPDEIEAEIEAWLDKPLDCAASDGLGKARRLDDAAGRYIEFCKSTFPAAFDLRGMKLVVDCAHGAAYQVAPHVFHELGADVIPIGVAPNGFNINDGVGATAPDALMRAVRANHADLGIALDGDADRLLVVDHTGRLYNGDELLYVLVKDRIATNGQVEGAVGTLMTNFAVEVALKEAGVQFVRAAVGDRYVLEQLREHGWQLGAEGSGHILSLDRHSTGDGIVSALLVLAALKRSGKTLAQMLEGVTLFPQKLINVRMKPGADWKGSDAIRRAIDSAEQALSGSGRVLIRASGTEPVLRVMVEARQATDANRHAEAIADAVKQATA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: SPRTL_STRTD
Sequence: MNLTDYVKTVSIEDFGWKFKHQALWNKRLRTTGGRFFPKDGHLDFNPKLYEEHGLETFRKIVRHELCHYHLYFQGKGCKHGDRDFKDLLARVDGLRYAPKMRNQAENYFLYQCQSCGHTYRRKRRVNTQKFGCGLCQGKLIFLNQS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16P1_HUMAN
Sequence: MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHSAQ
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis.  Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells.  Appears to modulate glycerol gluconeogenesis in liver.  Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
What are the official names of this protein?
Fructose-1,6-bisphosphatase 1, FBPase 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1, Liver FBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
Protein: Y675_TREPA
Sequence: MNTTGRPVFPLLRRTVLKRCSLCATRCAIVFLCVLLILPFLSCCTSLSRGALPSLISHKERMFWEIRGPQGSVYILGTISVGSEKLLHFQDKILDVFDSASRLYAELGSEDIKNFASVLQRRMLHGMLEQENAAPTLSSLSREELEMLRSTLGDDMHTLSRFEPWVMRVALYQALIAHTKLDSGKNIEAFLYQRAGNRKILGLDSIQKHLNMLSFGNREEQITLLRALIALGKSPADFKGRLGALVRSYLSNDKTALGRVSTELDALVTKDAAGGLHRRYVAEIAASRRAAWAEEFYRLSLQHGITFVFASAGHFCGPESVFDIMRKRRLLQ
What are the official names of this protein?
Uncharacterized protein TP_0675.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RSBW_LISMO
Sequence: MATMHDKITLQLPAKPEYVSLGRLSLSGIASRAGFSYEAIEDLKIAVSEAITNSVKHAFKGEEDGEITVEYLIYEDKLEVRVSDNGTSFDLETRKQEIGPYDVGEDAEMMRIGGLGLFLIETLMDDVKLYYDEGVSVVMTKYINEKQVEENAKSIST
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: TRUD_SALA4
Sequence: MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: ENO_RHOPS
Sequence: MTAIVDIIGREILDSRGNPTVEVDVVLEDGSVGRAAVPSGASTGAHEAVELRDGDKARYLGKGVLKAVEAVNGELFDALGGMDAEQQVQIDQTMIELDGTPNKGRLGANAILGVSLAVAKAAASSYDLPLYRYVGGTSARTLPVPMMNIINGGAHADNPIDFQEFMIMPVGAASFSEALRCGSEIFHTLKGELKKAGHNTNVGDEGGFAPNLPSADAALDFVMAAIGKAGYKAGEDVMIALDPASTEFFKNGKYVYEAEGRSLGPQEQAKYLADLVARYPIVSIEDGMAEDDIEGWKAITDLIGDKCQLVGDDLFVTNVTRLADGIKNGYANSILIKVNQIGTLTETLAAVEMAHKAGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLARADRTAKYNQLLRIEQELGAQAHYAGKAALKAFR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GGPPS_NEUCR
Sequence: MEHVTMAVTSSSPGPAPLSLLSNNDDFIAPFNINTKFPSAIVPPRTSSNQPISVAIPSNRISSAGLAATQQAQTRKRKASVAQISLPSMLPTSFSPYTMAPQPPQPPPNPDRFATEDFFSPSRRTWSEEKEKVLTGPYDYLNGHPGKDIRSQMVKAFDAWLDVPSESLEVITKVISMLHTASLLVDDVEDNSVLRRGFPVAHSIFGIPQTINTSNYVYFYALQELQKLKNPKAVSIFSEELLNLHRGQGMDLFWRDTLTCPTEDDYLEMVSNKTGGLFRLGIKLMQAESRSPVDCVPLVNIIGLIFQIADDYHNLWNREYTANKGMCEDLTEGKFSFPVIHSIRSNPSNMQLLNILKQKTGDEEVKRYAVAYMESTGSFEYTRKVIKVLVDRARQMTEDIDDGRGKSGGIHKILDRIMLHQEENVAQKNGKKE
What is the function of this protein?
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase, GGPP synthase, GGPPSase, (2E,6E)-farnesyl diphosphate synthase, Albino-3 protein, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranylgeranyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP4D_CHLMU
Sequence: MQNKRKLRNDFIKIVKDVEKDFPELDLKIRVNKERVTFLNSPLELYHKSISLILGLLQQIEKSLELFPDSPVLEKLEDNSLKLKKALIMLILSRKDMFSKAE
What are the official names of this protein?
Virulence plasmid protein pGP4-D.