PharMolix/UniProtQA huggingface dataset:
Protein: H2AB2_HUMAN
Sequence: MPRRRRRRGSSGAGGRGRTCSRTVRAELSFSVSQVERSLREGHYAQRLSRTAPVYLAAVIEYLTAKVLELAGNEAQNSGERNITPLLLDMVVHNDRLLSTLFNTTTISQVAPGED
What is the function of this protein?
Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo.  They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase.  They associate with spliceosome components and are required for mRNA splicing.  May participate in spermatogenesis.
What are the official names of this protein?
Histone H2A-Bbd type 2/3, H2A Barr body-deficient, H2A.Bbd.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with the active X chromosome and with autosomes, while it is absent from the inactive X chromosome and excluded from Barr bodies.
Protein: NTPPB_NITMU
Sequence: MKTQQIAQQLILGSSSIYRRDLLQRLQIPFDVSNPDIDETPLPGETPDATAVRLAAAKTRAVAATHPGALIIGADQVAVFEGIQLGKPLNHLNATRQLQLIRGKEVSFYTALCLFNSAQDTTRARLVPSRVKFRLLSDRQIENYLDKEQPYHCAASSKLEGLGIALIEHMEGEDPTALIGLPLIALVEMLTLEGVEIV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABG_RICBR
Sequence: MIDLSGQTALITGASGGIGGAIARQLHKLGSHVIISGSNEEKLKALGNDLKDNYTIKVCNLTNTEECSNLVAQIEKLDILVCNAGITKDTLAIRMKNEDFDQVIDINLKANFILNREAIKKMMTNRYGRIINITSIVGVSGNPGQANYCASKAGLIGMTKSLAYEVATRGITVNAVAPGFIKSDMTDKLNDEQKEAITRKIPKGTYGMPEDIANAVAFLASKQSSYITGQTLHVNGGMLMV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase FabG, 3-ketoacyl-acyl carrier protein reductase, Beta-Ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: LETM1_DANRE
Sequence: MASILLTRSRTPLLKTSRSLKNEFRKGKLSEGACFNCTALRLATNSPGVLGGIVWPHASSVQYLDNSSVLQRRLSRSPRLYCAILVPDPALPVHSRSTYHRTLAWPQNAPVRWVHTTGRLLDDSKVERSLRTLKDRNKKLEEGGPVYSPTVDAEPVRRTIRQRVIDEVKHYYHGFRLLWIDTTIAVRMLWRVLNGHILSRRERRQFLRTCADVFRLLPFLVFIIVPFMEFLLPVALKLFPNMLPSTFETQSKKEERLKKELRVKLEMAKFLQDTIEEIALRNKASKGNVTEEFSTFFQKIRDSGEIPSNEQIIRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLIMKLRAIRADDKLIAEEGVDSLTANELQAACRVRGMRALGVTEERLREQLKQWLELHLNQHIPTSLLLLSRAMFLPDTLSPADQLKTTLQNLPEIMAKEAQVKVAELDFSKVDNKTKLETTLQEEAAIRQENRERELERLADAAEKAKEQTQSQEAEVLEVEGERRVDAEHALSSVDVAIHSETLRDTAPVLEGIKGEEITKEEIDMLSDACTKLKEQKNLLTKEKEELEDLKDDVQEYSEDLEEIKRELSKTGQEKAVEESKASQRLSKRVNRMIGRMDKIITELEKDKMVLDGQMDSETTPPIGENLISINELITVMKQIQNIPEHKLLSIADALDENKDGKIDIDDVIKVVELIDKEDIDISTNQVAEIMVMLQKEEKLMEKEKAKEKVEKEQAAKIQN
What is the function of this protein?
Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport (By similarity).  Mediates proton-dependent calcium efflux from mitochondrion (By similarity).  Functions also as an electroneutral mitochondrial proton/potassium exchanger (By similarity).  Required for the maintenance of the tubular shape and cristae organization (By similarity).
What are the official names of this protein?
Mitochondrial proton/calcium exchanger protein, Electroneutral mitochondrial K(+)/H(+)exchanger, KHE, Leucine zipper-EF-hand-containing transmembrane protein 1.
What is the protein family that this protein belongs to?
Belongs to the LETM1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: QUEA_SYNAS
Sequence: MMKLQDFDYQLPQSRIAQSPCAKRDHARMMVLDRRIGSLEHRHFYDFPDFVRKGDVLVINDSKVIPARLSGRKETGSRIELLLLSRYSDSPAVPETDSTEWPFFRVGVEETWEALLKPGKRIRIGTSIFFDDHSRATVIERINEKKWLLTFNTALPFDLFLQRYGKAPLPPYIKREKKNAQMPEDRDRYQTIYARSPGSIAAPTAGFHFSEALFKTLRELEIVIAPVTLHVGFGTFTPIETEDVEDHVMEVESFSISPESSDKINSAERVIAVGTTSTRVLESAADEQGRVHPMSGQSRLFIYPGYRFKRVQALLTNFHLPKSSLFLLACAFAGKDRIQQAYATAIQEEYRFYSYGDCMLII
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPPA_PICTO
Sequence: MAIAMIPKTMSTQHPDNAKMPAWASEKSMIRNDDEVEEAYQCYTIGIKEVMWDAEGKDVDTHVLRKLISKNHEFFEKNVLGSDIFLTYRVPNPAIEGTERKVLTETLESIPVNYDVFNTVYKRDIPPIFEVILPFTTSSKDLLNIAKYYEKAVAARDEIELYDNVMVKNILGETKPKKINIIPLIEDKDSMFNIDGIVKNFARAVSAKKMRVFIARSDPAMNYGMIPAVLMSKYAASRLCKMNDDIENYPIVGVGSSTFRGRFSPENIEKSLYEYSNYYTFTLQSAFKYDYPQDSVKNSINIINRHERSFDYLEDYEEEIIKNAVNKYVINYQKIIEKLAPAINNITMYLPKRRSRKLHIGLFGYSRSTGNVTLPRAISFVGAMYSMGLPPEIIGISSLLNMKDDELDIIEKTYINLRSDIMESSSYLNYEVFDALKDVYKIDQETINMIKADVKYIENNYGIKSDLGYERERHNYLSSLMNLAFKNHDFENTRKYILDMALIRKFIG
What is the function of this protein?
Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 2 family.
Protein: KGUA_RUEST
Sequence: MAHSKAQRRGLLIILSSPSGAGKSTLAKRLRAWDSDISFSVSATTRKPRPGEVDGQDYHFVTVESFKQDVANGDMLEHAHVFGNFYGSPKGPVQTAINEGRDVLFDIDWQGAQQITNSDLGKHTLSIFLLPPSITELRRRLESRGQDDAETISRRMQKSWDEISHWGSYDHVLINEDLDETEEALKTIITATRLRRIQQPSLIEHARALQQEFEDLS
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_RHILO
Sequence: MPKRILQGTVVSDKNEKTVVVKVERRFTHPVMKKTVRMTKKYKAHDENNAHKVGDQVFIQESKPISKDKRWIVVSSDQA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: HIS2_MYCTU
Sequence: MQQSLAVKTFEDLFAELGDRARTRPADSTTVAALDGGVHALGKKLLEEAGEVWLAAEHESNDALAEEISQLLYWTQVLMISRGLSLDDVYRKL
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEN3I_PENVA
Sequence: MRLVVCLVFLASFALVCQGQVYKGGYTRPIPRPPPFVRPLPGGPIGPYNGRPVSCRGISFSQARSCCSRLGRCCHVGKGYSG
What is the function of this protein?
Antibacterial and antifungal activity.  Presents chitin-binding activity (By similarity).
What are the official names of this protein?
Penaeidin-3i, Pen-3i.
What is the protein family that this protein belongs to?
Belongs to the penaeidin family.
What are the subcellular locations of this protein?
Cytoplasmic granule. Note=Cytoplasmic granules of hemocytes and to a lesser extent in small granules of hemocytes.
Protein: NUOB_PARXL
Sequence: MSIEGVLKEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDLDRFGVVFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGVIQLQAKIRRTNTIARQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LSPA_BEII9
Sequence: MSPRVLGGLAAFLCLVLDQANKLWLIHVFDIEARRPVRLAPFFDIIYERNPGISYSLFRAQSAMGRWILVALTLFAILLLSIWLWRATNRLVALALGCIIGGALGNAIDRIAAGAVADFYYFHIGSFSWYVFNLADAAIVAGVALLILDAFTSEEAGVPAPDSEGHS
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHDC_BACC4
Sequence: MSEATTTLDGWYCLHDLRSIDWAAWKTLSSDERGQAVSEFLNVVEKWNEVATAKKGSHAMYTVVGQKADIMLMILRPTMEELNEIETELNKTTLAEYMVPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPKANHICFYPMDKRRQGDDNWYMLPMEERKKMMYSHSKIGRQYAGKVRQVISGSVGFDDFEWGVTLFADDVLQFKKLIYEMRFDEVSARYGEFGTFFVGNILPDEKVEKFLHI
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway.  The reaction occurs in a stepwise manner with a three-propionate intermediate.
What are the official names of this protein?
Coproheme decarboxylase, Coproheme III oxidative decarboxylase, Hydrogen peroxide-dependent heme synthase.
What is the protein family that this protein belongs to?
Belongs to the ChdC family. Type 1 subfamily.
Protein: CC2H1_TRYBB
Sequence: MGSRYERLQKIGEGSYGVVFRARDVTTGTIVAVKRIRLEKEEEGVPCTAIREISILKELRHENIVRLLDVCHSEKRLTLVFECMEMDLKKYMDHVGGDLDAGTIQEFMRSLLSGVRFCHERNVLHRDLKPPNLLISREKELKLADFGLGRAFGIPVKKFTQEVVTLWYRSPDVLLGSTQYGTPVDIWSVGCIFAEMAIGAPLFTGKNDADQLLRIFQFLGTPNRQVWPSMDTYPNSSNMLSRPEFQQTLAATCEEQFQTNPAYAKLGPQGIDLLRWLLRYEPSERLTAAQALEHPYFSVEF
What is the function of this protein?
Probably involved in the control of the cell cycle.
What are the official names of this protein?
Cell division control protein 2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: FADI_YERPN
Sequence: MSKPLPLVTRQGDRIVIVNGLRTPFAKQATAYHGVPAVDLGKIVVSELLARSGISSELIDQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESIIAGSVDIAIAGGADSSSVLPIGVSKALARTLVDANKARSLSQKLKLFSRLRLRDLLPVAPAVAEYSTGLRMGDTAEQMAKTYGISREDQDALALRSHQLAAEAWQQGWLHDEVMTAYIPPYREAIIEDNNIRKDSTLAQYAKLRPAFDRQHGSVTAANSTPLTDGAAAVLMMSESKAKALGLPPLGYLRSFAFSAIDVWQDMLLGPSYATPLALDRAGITLADLTLIDMHEAFAAQTLANLKMFASDTFAREKLGRSQAIGEVDMSKFNVLGGSIAYGHPFAATGARMITQTLNELRRRGGGLGLTTACAAGGLGAAMILEVE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_PSEMY
Sequence: MEFGLREWLIVIGIIVIAGILFDGWRRMRGGKGRLKFKLDRSFANMPDDDSDPDLLSPPRVVKREMEPQLDEDDLPSMSAKELPRRSRNEPQQGDLNLAVDEPVPTLLNPVDDKPQEPKKSAKLSAEAAPVEEVLVINVVARDDLGFKGPALLQNILESGLRFGEMDIFHRHESMAGNGEVLFSMANALKPGTFDLDDIEGFSTRAVSFFLSLPGPRHPKQAFDVMVAAARKLAHELGGELKDDQRSVMTAQTIEHYRQRIVEFERRQLTQKR
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: DCUP_PSEAE
Sequence: MTALKNDRFLRALLKQPVDVTPVWMMRQAGRYLPEYRATRAKAGDFMSLCMNPELACEVTLQPLDRYPQLDAAILFSDILTIPDAMGQGLYFETGEGPRFRKVVSSLADIEALPVPDPEQDLGYVMDAVRTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKSKAMLYDNPKAMHALLDKLAQSVTSYLNGQIHAGAQAVQIFDSWGGSLSAAAYQEFSLAYMRKIVDGLIREHDGRRVPVILFTKGGGLWLESMAEVGAEALGLDWTCDIGSARARVGERVALQGNMDPSVLYANPAAIRAEVARILAAYGKGTGHVFNLGHGITPEVDPAHAGAFFEAVHELSAQYHG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1C_CHLSC
Sequence: MKEQKLIHEGLITESLPNGMFRVRLDNEDLILGYVSGRIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKDSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRPB_BACCQ
Sequence: MNYAYPDEKGHYGIYGGRYVPETLMQSVLELEEAYKEAMEDEEFQKELNHYLKTYVGRETPLYFAENMTKYCGGAKIYLKREDLNHTGAHKINNTIGQALLAVRMGKKKVVAETGAGQHGVATATVCALLGLECVIFMGEEDVRRQKLNVFRMELLGAKVESVAAGSGTLKDAVNEALRYWVSHVHDTHYIMGSVLGPHPFPQIVRDFQSVIGNETKKQYEALEGKLPEAVVACIGGGSNAMGMFYPFVHDEEVALYGVEAAGKGVHTEKHAATLTKGSVGVLHGSMMYLLQNEEGQIQEAHSISAGLDYPGVGPEHSLLKDIGRVSYHSITDDEALEAFQLLTKKEGIIPALESSHAVAYALKLAPQMKKDEGLVICLSGRGDKDVESIKRYMEEV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GLNA2_DAUCA
Sequence: MAQILAPSVQWQMRFTKNSTEVSSMTSKMWGSLFLKQNKKAPARSSTKYRALAVKSEDGTINRMEDLLNLDVTPYTDKIIAEYIWIGGTGIDVRSKSRTISKPVEHPSELPKWNYDGSSTGQAPGDDSEVILYPQAIFKDPFRGGNNILVICDTYTPQGEPIPTNKRHKAAQIFSDAKVLGEVPWFGIEQEYTLMQQDVNWPLGWNVGGYPGPQGPYYCAAGADKSFGRDISDAHYKACLYAGINISGTNGEVMPGQWEFQVGPSVGIEAGDHIWCARYLLERITEQAGVVLTLDPKPIDGDWNGAGCHTNYSTKSMREEGGFEVIKKAILNLSLRHKEHISAYGEGNERRLTGKHETASIDSFSWGVADRGCSIRVGRDTEKEGKGYLEDRRPASNMDPYVVTGLLAETTLLWEPTLEAEALAAQKLSLNV
What is the function of this protein?
The light-modulated chloroplast enzyme, encoded by a nuclear gene and expressed primarily in leaves, is responsible for the reassimilation of the ammonia generated by photorespiration.
What are the official names of this protein?
Glutamine synthetase, chloroplastic, GS2, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ARGB_NEIMA
Sequence: MESENIISAADKARILAEALPYIRRFSGSVAVIKYGGNAMTEPALKEGFARDVVLLKLVGIHPVIVHGGGPQINAMLEKVGKKGEFVQGMRVTDKEAMDIVEMVLGGHVNKEIVSMINTYGGHAVGVSGRDDHFIKAKKLLIDTPEQNGVDIGQVGTVESIDTGLVKGLIERGCIPVVAPVGVGEKGEAFNINADLVAGKLAEELNAEKLLMMTNIAGVMDKTGNLLTKLTPKRIDELIADGTLYGGMLPKIASAVEAAVNGVKATHIIDGRVPNALLLEIFTDAGIGSMILGGGEDA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 028R_IIV3
Sequence: MDQYITLVELYIYDCNLFKSKNLKSFYKVHRVPEGDIVPKRRGGQLAGVTKSWVETNLVHFPLWLSEWDETRWGVLNHYPLESWLEKNVSSKVPVNPVMWNFDSECLVYFFHNGRRTPFLTPKGVVKLQVFYNLMSGKEVEWFYEISNGFLKPHLHQLSNVRELVRLKHAPVVVGAGGPRLVTEGVYSLRDDDFVVDCSQIAAVKRAIERGESHQSLRKYQCPLFVALTDKFQDTVKLVEKKFEVQLNELKAETTIQVLREQLRQEKKLKEQVLSLTQSFIPTIGGRGEEFGKPDETPSSASVGDDNFPSSTNHTFEARRRPSSLSSGGALKPSKIL
What are the official names of this protein?
Uncharacterized protein 028R.
Protein: RISB_PASMU
Sequence: MKVLEGAVAAPNAKIAVVIARFNSFINESLLEGALDALKRLGQVKEENITLVRVPGAYELPLVARRLAESKKYDGIVALGTVIRGGTAHFEYVAGEASSGLGQVAMNADIPVAFGVLTTENIEQAIERAGTKAGNKGAEAALVALEMVNLLAQIDAA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SYT_LEPIN
Sequence: MYQLTLPDKSIKEVASGFTYRDFIEKELPFLKNKALAVRLNGEEILDLSRTVEKNSNIEVLTYSEKLGWETFQHSAAHLLGMAVQNLYKNANLTVGPVIDNGPGFFYYDIDFQGAIVTPEDFPKIEAEMEKIVKADHPVWRKVVSKKQAIETFQKLGEKYKIEIIDGIPSEEVSIYGMGEWFDLCRGPHVPNSGILKSFKLTAISGAYWKADKNNSMLTRIYGVAFPTKKELDQYLFQIEEAKKRDHRKIGKEMDLFSFQKEGPGFPFWHPKGTILWNSLAEYLRSECNKRGYQEIKTPAVLSSELWKKSGHWDNFHENMYFTDIDEEDYALKPMNCPGCSLIYKHHLHSYRELPLRFAEFGSVHRHELHGVLHGLFRVRAFTQDDSHIYAPLDYLESEVMDIIDFTFTVYKKFGFSEFKTFIATRPEKSQGKDEDWEFATSTLKQSLEKKGIPYGIKEGEGAFYGPKIEFNIKDSIGRLWQCGTIQVDFSMPERFDLDYTDSDGQKKRPVMIHRAIYGSLERFIGILIEHYEGKFPLWISPNQIRILTVTEKVTDYAKNVYRELLDSGFRVELDTRNEKIGAKIRDSILKKANYLLILGEKEMESNTLAVRMRGQEDTKILTRTGFISNLQDEIKSS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_BACAA
Sequence: MATEKTYPMTQEGKQKLENELEDLKTVKRKEVVERIKIARSFGDLSENSEYDAAKDEQAFVEGRITQLENMIRNAVIITDNGEESTVVTLGKTVTFKELPNGDEEAYTIVGSAEADPFEGRISNDSPIAKSLLGKQIGEKVAIQTPGGEMQVEIISVK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: TM214_RAT
Sequence: MAARAAGSGGWEVVKRSRRPGASSGGRGGGGDRRALGEANGVWKYDLSSPIQPTSTLYERGFEKIMKRQNKEQVPPPAAESKKPVNKKQPKKVTAVASQNQKQGPFRSLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKSLSPFAIAYLDRLLLMYPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLTSWEQIPKKARKCLQETIQSFTLTNQELLKKGSGSNEHVVTCDTACKGLLQQARGPRPPWARLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLQSSGLLPVAQQVCAKLYSYSLQSYNWLQETLPACGSYLLAVVQPSLQLAWTYIYATFSFLSAYCASYLAFFSDSLAGVLQRVQLPEALHQLFHSLKELLLLFYHSVLLPMWHLLLAALAQVQEHCHEACRGEMTWDCIKTQFSTAAHWTWLCLQDVTVAFLDWALTMISQQ
What is the function of this protein?
Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis.  Required or the activation of CASP4 following endoplasmic reticulum stress (By similarity).
What are the official names of this protein?
Transmembrane protein 214.
What is the protein family that this protein belongs to?
Belongs to the TMEM214 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IRAP_ECOHS
Sequence: MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ
What is the function of this protein?
Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation.  Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway.
What are the official names of this protein?
Anti-adapter protein IraP.
What is the protein family that this protein belongs to?
Belongs to the IraP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQP2_DASNO
Sequence: SVAFSRAVLAEFLATLIFVFFGLGSALSWPQALPSVLQIALAFGLAIGTLVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPPDVRG
What is the function of this protein?
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
What are the official names of this protein?
Aquaporin-2, AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Shuttles from vesicles to the apical membrane. Vasopressin-regulated phosphorylation is required for translocation to the apical cell membrane. PLEKHA8/FAPP2 is required to transport AQP2 from the TGN to sites where AQP2 is phosphorylated.
Protein: RS20_CLOAB
Sequence: MANIKSAKKRIKVIETKTLRNKMIKSALKTYIKKFEAAFEAKNVEESKTAFATVSKALDMAASKGIIHKNKAARKKSRLALKLNSLNA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.