PharMolix/UniProtQA huggingface dataset:
Protein: XERS_STRU0
Sequence: MRRELLLEKIEEYKAIMPWFVLDYYQSKLSVPYSFTTLYEYLKEYKRFFDWLIDSGISDAPRIADIKLDVLEHLTKKDMESFILYLRERPSLNTYSTKSGVSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVATKKKKETLASRAENIKQKLFLGDETMEFLDYVDCEYENKLSNRAKSSFQKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLKMMVIEVTRKGGKRDSVNVASFAKPYLEHYLEIRQKRYKADKQDQAFFLTEYRGVPNRIDASSIEKMVGKYSQDFKIRVTPHKLRHTLATRLYDATKSQVLVSHQLGHASTQVTDLYTHIVNDEQKNALDKL
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.
What are the official names of this protein?
Tyrosine recombinase XerS.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerS subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NB5R4_RAT
Sequence: MLNVPSQAFPAPGSQQRVASQGRSKVPLKQGRSLMDWFRLTKSGKDFTGLKGGLIEVTEEELKKHNKKDDCWICIRGFVYNVSPYMEYHPGGEDELMRAAGADGTDLFNEVHRWVNYESMLKECLVGRMAVKPAVPKDCHEGKRVLNGMLPKSQVTDTLPREGPSSPSYDWFQTESSVTIVIYTKQKNINLDSVIVDLQDDSLRAEAVIKDHSYLIHIGLSHEVQENFSVRVIENVGKIEIVLQKKETVSWKCLGDPLEKHDSFIPKKDTGLYYRQCQLISKEDVTHDTRLFCLMLPPSTHLQVPVGQHVYLKLSVTGAEIVKPYTPVSESLLSDFKEPVLSPNKYIYFLIKIYPAGLFTPELDRLQIGDFVSVSGPEGNFKVSKLQEVEDLFLLAAGTGFTPMVTVLNHALTHMSSLRKVKLMFFNKTEDDIIWRCQLEKLALKDKRFHVEYVLSAPSPEWNGKQGHVSRALLSEFLQRSLENSKVFLCICGPTPFTDEGIRLLHDLNFSDDEIHGFTA
What is the function of this protein?
NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway.  Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS).
What are the official names of this protein?
Cytochrome b5 reductase 4, Flavohemoprotein b5/b5R, b5+b5R, N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein, cb5/cb5R.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=Soluble protein.
Protein: CYB6_KLEBI
Sequence: MGKVYDWFEERLEIQAIADDVTSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYLMTDVNFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVILAVLTVSFGVTGYSLPWDQVGYWAVKIVTGVPEAIPVIGSPLVELLRGSVSVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PUR9_BURMS
Sequence: MIKQALISVSDKTGIVDFAKALSALGVKLLSTGGTAKLLADAGLPVTEVADYTGFPEMLDGRVKTLHPKVHGGILARRDLPEHMQALEAHGIPTIDLLVVNLYPFVQTIAKDDCTLADAIENIDIGGPTMLRSAAKNHRDVTVVVDPADYAVVLDEMKANGNTLGYKTNFRLATKVFAHTAQYDGAITNYLTSLGDDLQHGSRSAYPATLNLAFDKVQDLRYGENPHQSAAFYRDVATPAGALANYRQLQGKELSYNNIADSDAAWECVKTFDAPACVIIKHANPCGVAVGADAGEAYAKAFQTDPTSAFGGIIAFNREVDEAAAQAVAKQFVEVLIAPSFSDAAKQVFAAKQNVRLLEIALGEGHNAFDLKRVGGGLLVQSLDSKNVQPRELRVVTKRHPTPKEMDDLLFAWRVAKYVKSNAIVFCGNGMTLGVGAGQMSRVDSARIASIKAQNAGLTLAGSAVASDAFFPFRDGLDVVVAAGATCVIQPGGSVRDDEVIAAADEHNIAMVVTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: EFTS_DICT6
Sequence: MEITIEMIKELRERTGAGVMEAKKALEEANGDMEKAVTILREKGVIKAAKKAGRVAKEGIIEAYIHTGDKLGVLVEVNCETDFVARTDEFRKLAKDIALQIAGMNPQYVSKEDVPPEVIEKEKEIYRTQLKNEGKPEHVIEKIIEGKLEKFYEEVCLLEQPFVRNPEIKVKDLITEAISKLGENIVVRRFARFVVGED
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_MICAN
Sequence: MGNKPTIAISHLGCEKNRIDSEHMLGLLAKAGYPVDNDEELADYVIVNTCSFIQAAREESVRTLVELAEANKKIIISGCMAQHFQDELLTELPEAVAIVGTGDYQKIVEIVERVETGERVKEVSADPTFIADENLPRYRTTSEGVAYLRVAEGCDYRCAFCIIPQLRGDQRSRSIESIVAEARQLASQGVQELILISQITTNYGLDLYGEPKLAELLRALGEVDIPWIRVHYAYPTGLTPKVIEAIRETPNVLPYLDLPLQHSHPDILRGMNRPWQGRVNDGIIERIKQAIPNAVLRTTFIVGFPGETEEHFSHLLEFVKRHEFDHVGVFTFSAEEGTAAFDLPDPVPQAIMDERRERLMLTQQPISERKNQAYIGQTVDVLIEQENPETGELIGRSARFSPEVDGLVYVTGEAILGAIVQVRITAADTYDLYGEIV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_LEPBL
Sequence: MSMSDPIGDMLTRIRNAGRAKHDTCLVPGSKIKKSILDLMKEEGFIRDYESVKVNETFEDYKVFLKYDQTKRPIIRELIRVSTPGRRVYIKSTEIRPYKNNIGTLIVSTSKGIMTGKNARKLKLGGEVILKMS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CLPX_STRP1
Sequence: MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGKSKPVLETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SNN_HUMAN
Sequence: MSIMDHSPTTGVVTVIVILIAIAALGALILGCWCYLRLQRISQSEDEESIVGDGETKEPFLLVQYSAKGPCVERKAKLMTPNGPEVHG
What is the function of this protein?
Plays a role in the toxic effects of organotins (PubMed:15269288).  Plays a role in endosomal maturation (PubMed:27015288).
What are the official names of this protein?
Stannin, AG8_1.
What is the protein family that this protein belongs to?
Belongs to the stannin family.
Protein: CH10_HAEIN
Sequence: MNIRPLHDRVIIKREEVETRSAGGIVLTGSAATKSTRAKVLAVGKGRILENGTVQPLDVKVGDIVIFNDGYGVKSEKIDGEEVLIISENDILAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_AZOSB
Sequence: MLVHPQFDPVAIAVGPVAVRWYGLMYLLAFVLFVVLGRAHARRRPELGWNAQAIDDLLLYGVLGVIIGGRLGEVLFYQPGYYLSHPAEILAVWKGGMSFHGGFLGVLVAMWLYGQRSGRGFWQITDFIAPLVPTGLAAGRIGNFINGELWGRPASPDLPWAMIFPWVDALPRHPSQLYQAAGEGLLLFAIVWVFAAKPRPLRAVSAVFLIGYGSLRFVAEFFRTPDPGIFSDLVPGLSTAQWLCVPMVVVGLALLKHAAHARARG
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTX3_XENLA
Sequence: MMELRCWGSDWGLPSVHPECLVVLAYARFAGAPLKVTPVDYTWASPKGTVPFLTSAGEDTHQPANILNFFRKQKYNADYVLSAKEGSDTLAYIALLEEKLLPAVLHTFWVDTENYCNVTRPWYASHTPFPLNYYLPGKMSRDALDRILVTRGQPPLYSLSEVEAQIYKDAKECLNLFSNRLGTAQYFFGSTPTSLDAFVFGFLAPLYKAHLHKVNLQQHLKQLSNLCHFCDHILSAYFVSDDAGTSAAGQEAIDANLQKLTQLVNKESNLIEKMDDNLRRSPQNRPQKLSTLKPVGGAENSHSSDLLSH
What is the function of this protein?
Could function in transport of proteins into the mitochondrion.
What are the official names of this protein?
Metaxin-3, xMTX3.
What is the protein family that this protein belongs to?
Belongs to the metaxin family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion outer membrane.
Protein: APC10_MOUSE
Sequence: MTTPNKTPPGADPKQLERTATVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR
What is the function of this protein?
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.  The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity).
What are the official names of this protein?
Anaphase-promoting complex subunit 10, APC10, Cyclosome subunit 10.
What is the protein family that this protein belongs to?
Belongs to the APC10 family.
Protein: ILVC_HALWD
Sequence: MTETKTQTETETDEEEGTDTDTALDTTIYYDDDADREYIDDKTVAVLGYGSQGHAHAQNLADSGIDVIVGLYEGSSSRDAARADGLRVETPATAADEADIVSVLVPDTVQPDVFEAIQDGLDAGDTLQFAHGFNIHYNQIQPPADVDVTMVAPKAPGHLVRRNYEAGEGTPGLVAVYQNTTGTARKEAVAYAHAIGCTRAGAIETTFREETETDLFGEQAVLCGGATALVKQGYETLVDAGYSPEMAYFECLNELKLIVDLMYEGGLSEMWNSVSDTAEYGGLTRGNQVIDESVREEMESILEGVQDGTFAREWISENQANRPSYTQLKAAEEAHEIEAVGEPLRDLFAWSDNEETNDESDVVSEPEAAADD
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: KEFC_SALPB
Sequence: MDSHTLLQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFVIGLELDPQRLWKLRASVFGGGALQMVVCGGLIGLFCMFLGLRWQVAELIGMTLALSSTAIAMQAMNERNLTVSQVGRSAFAVLLFQDIAAIPLVAMIPLLAASGASTTLGAFALSALKVAGALALVVVLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLVENPLRILLLLAGFLAIKIVMLWLVARPLGVPAKQRRWFAVLLGQGSEFAFVVFGAAQMADVLEPEWAKALTLAVALSMAATPIFLVLLTRMEKTATGEAREADEIDEEQPRVIVAGFGRFGQIAGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLSELVKSHFPHLQIIARARDVDHYIRLRQAGVAMPERETFEGALKSGRQALEALGLGRYEARERADLFRHFNTRMVEEMAKGENDPLSRAAAYKRTSAMLSEIITEDREHLSLIQRHGWQGTAEGKHSGEVADEPEVKPSI
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS16_MALP2
Sequence: MVKIRLTRLGRHKLPFFRIVVIDSRARRDGAYIEKVGTYEPFEGVVNINEEIALSWLKKGAQPSDTVKNLLREQGVWKKFMDSKVQSKKEHNANKVKKEVKKPEAKKAAASKPASKPSASKSASQKKTVSKK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SEM4G_MOUSE
Sequence: MWGRLWPLLFSFLTVTAVPGPSLRRPSRELDATPRLTISYEELSQIRHFKGQTQNYSTLLLEEASERLLVGARGALFSLSARDIRDRTHKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNATHFYACGTHAFQPLCAAIDAETFILPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEFVFSVLVRESKTSAVGDDDKIYFFFMEREEGSSSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIPQYETLRGVCSLNADTSSHTHFYAVFTLTTQWKTLEASAICRYDLAEIQAVFTGPFMEYQDGARRWGRYEGGVPEPRPGSCITDSLRSRGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNVRYTHLTGTHVSTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEEIQVFREPQSVDNLVISPMQHSLYVGAASGVLQFPLSSCSRYQSCYDCILARDPYCGWDSSIHACMVATTVANRTELIQDIERGNRGCEGSRDAGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSKSLSDGQDGYRVGVDGLLVTDTQLEHSGNYGCYAEENGLRMLLASYSLTVRPATPAPAPQAPATPGAQLAHDMRMFYVVAIAILGGLCLILASSLLYVACLKGGRRGRRRKYSLGRAGRAGGSAVQLQTVSGQCPGEEDEGDDGEGTGGLESGCLQIIPGEGAPAPPPPPPPPPPAELTNGLVALPSRLRRMNGNSYVLLRQSNNGVPAGPCSFAEELSRILEKRKHTQLVEQLDESSV
What is the function of this protein?
Cell surface receptor for PLXNB2.  May play a role in axon guidance.
What are the official names of this protein?
Semaphorin-4G.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: VF177_ASFB7
Sequence: MWKVNDQGFLNITVTGTKFNLIAITGKLGFYTDPPSHLMIMPLKIFPVHKFSKNEPNKKQKRFIYF
What are the official names of this protein?
Protein I177L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I177L family.
What are the subcellular locations of this protein?
Virion.
Protein: LDH1_LISIN
Sequence: MKDHQKIILVGDGAVGSSYAFACVNLSIGQEFGIIDIDKDRTIGDAMDLSHAVPFSTPKKIYSANYSDCHDADLVVVTAGTAQKPGETRLDLVNRNIKIMKGIVDEVMASGFDGIFLIASNPVDILTYATWKFSGLPKERVIGSGTSLDTARFRMSIADYLKVDARNVHGYILGEHGDTQFPAWSHTTVGGLPITEWINEDEQGAMDTIFVSVRDAAYEIINKKGATFYGVAAALARITKAILNNENAILPLSVYLDGHYGMNDIYIGAPAVVNRQGVRHIVEMNLNDKEKEQMKNSADTLKKVLDDAMKQID
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 1, L-LDH 1.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_CLOB6
Sequence: MAKSLLFGEQARRSMEAGVDKLADTVRVTLGPKGRNVVLDKKFGSPLITNDGVTIAREIELEDPYENMGAQLVKEVATKTNDVAGDGTTTATLLAQAIIREGLKNVTAGANPIQIRTGIRKAVEKAVEEIKVISKPVNGKEDIARVAAISAASEEVGKLIADAMERVGNDGVITVEESKSMGTDLEVVEGMQFDRGYVSAYMVTDTEKMEAVLDDVYILITDKKISNIQEILPILEQIVQQGKKLLIISEDIEGEALSTLVLNKLRGTFTCVGVKAPGFGDRRKEMLQDIAILTGGEVISEELGRDLKDVTIDMLGTADSVKVTKENTTIVNGKGDKVAIKERVSQIRVQIEDTTSEFDKEKLQERLAKLAGGVAVIRVGAATETELKEEKLRIEDALAATKAAVEEGIVPGGGTAYIDIIPKIADLTSDIIDVKLGIDIIRKALEEPVRQIANNAGVEGSVIIEKVKASEAGVGYDALNDKYVDMLKTGIVDPTKVTRSALQNAASIASTFLTTEAAVADIPEKENTPPMAPGMGMDGMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_RHILW
Sequence: MGIRSTSVSDAVAALDERSREIFRRIVEGYLESGEPLGSRNLSRLLPMSLSPASVRNVMSDLEDLGLIYSPHISAGRLPTQIGLRFFVDAFMQVGDLSAEDRASIDRQVRAESGGNPVESMMNEASRMLSGISRGAGLVITSKSDPVLKHVEFIRLEPTKALAVLVGDHDQVENRIIELPAGVTSSQLAEAANFLNAHMSGQTLPELRKQLSQLKDNVRHELDALSRDLVERGIAVWAGSPDEGKPAQLIIRGRANLLEGLAGAEDLDRLRLLFDDLEKKDSLIEILNLAETGSGVRIFIGSENKLFSLSGSSLIVAPYRDDDDRIVGAVGVIGPTRLNYSRIVPMVDYTAQLVSRLSRNPL
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: AF9_CRYNB
Sequence: MSSERVRGIQVHRPIIFGSHARLLTEAEKQLAPAGHTHKWTVFLNSAASPPLKQGEPPDYEDIDYLPGGADDLSYFIRKVTFKLHETYATPNRVIDKPPYRVSETGWGEFTVQIRIQLIPESSEKPLGLQHNIKLHHWGAPVEPLPVVSGAPTPTPVPTESNTEVKLEPDTPAPLEESVTPAPTIQRPASEPATNEPGSNQGTPAPPGGDSTEQIKVDVATPALEVIEPSATPAPLSLAARLPIHAWQYDEIVFSDPPRQFLDILNAHPPTPLPAKSRRPRDQREDYEARKKGKSAARGASVTASARASRAGTVDTAAAGTPAPAQIGIPGEPGSADVPLEFTQEMLKGEHNAMLDARVKIVEQMDRWRERLIALEKELAKAKEDVKATAAM
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity).
What are the official names of this protein?
Protein AF-9 homolog.
What is the protein family that this protein belongs to?
Belongs to the YAF9 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IF2_HELPG
Sequence: MSEMVDLKEFLAELGKTQKELKNVIEQAKDIGLELKTNSKMTPEEANKLYKYIVEGIKEQIQANQPAKNPEQDNKDDLNTAVASKPLNKKVSKTPKKEEKSQPKPKKTKEKKKEAPTPIAKKKGGIEIVNTFENQTPPVENNPKVVSHSQIEKAKQKLQEIQKSREALNKLTQSNANNAKKEISEVKKQEQEIKRHENIKRRTGFRVIKRNDEVENESENSVTESKKPTQSAAAIFEDIKKEWQEKDKQEAKKAKKPSKPKATPTAKNNKSHKIDFSDARDFKGNDIYDDETDEILLFDLHEQDNFNKEEEEKEIRQNINDRVRVQRKNPWMNESGIKRQSKKKRAFRNDNSQKVIQSAIAIPEEVRVYEFAQKANLNLADVIKTLFNLGLMVTKNDFLDKDSIEILAEEFHLEISVQNTLEEFEVEEVLEGVKKERPPVVTIMGHVDHGKTSLLDKIRDKRVAHTEAGGITQHIGAYMVEKNGKWVSFIDTPGHEAFSQMRNRGAQVTDIAVIVIAADDGVKQQTIEALEHAKAANVPVIFAMNKMDKPNVNPDKLKAECAELGYNPVDWGGEHEFIPVSAKTGDGIDNLLETILIQADIMELKAIEEGSARAVVLEGSVEKGRGAVATVIVQSGTLSVGDSFFAETAFGKVRTMTDDQGKSIQNLKPSMVALITGLSEVPPAGSVLIGVENDSIARLQAQKRATYLRQKALSKSTKVSFDELSEMVANKELKNIPVVIKADTQGSLEAIKNSLLELNNEEVAIQVIHSGVGGITENDLSLVSSSDHAVILGFNIRPTGNVKNKAKEYNVSIKTYTVIYALIEEMRSLLLGLMSPIIEEEHTGQAEVRETFNIPKVGTIAGCVVSDGVIARGIKARLIRDGVVVHTGEILSLKRFKDDVKEVSKGYECGIMLDNYNEIKVGDVFETYKEIHKKRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_STRMK
Sequence: MSHYEGDLRTPESARFAILASRWNARITDTLVAGARQSLAGNGIAEANIDVIRVPGAWELPLVAARLAAAHEHAAILTLGCVIRGDTRHYEHVADRCAEGLMRVQLDFGVPVLNGVLAVERVEDAEARAGGSHGNKGEEVALAALEMVNLLEQLP
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CYB_LEPEU
Sequence: MTNIRKTHPLLKIVNHSLIDLPAPSNISAWWNFGSLLGLCLMIQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWLIRYLHANGASMFFICLYMHVGRGIYYGSYTYLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMIHLLFLHETGSNNPSGIPSNSDKIPFHPYYTIKDALGFLMLILLLMLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIIPFLHMSKQRSMMFRPISQVLFWILVADLLTLTWIGGQPVEHPFITIGQVASILYFSIILILMPLASLVENKILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DDL_THET8
Sequence: MRVLLIAGGVSPEHEVSLLSAEGVLRHIPFPTDLAVIAQDGRWLLGEKALTALEAKAAPEGEHPFPPPLSWERYDVVFPLLHGRFGEDGTVQGFLELLGKPYVGAGVAASALCMDKDLSKRVLAQAGVPVVPWVAVRKGEPPVVPFDPPFFVKPANTGSSVGISRVERFQDLEAALALAFRYDEKAVVEKALSPVRELEVGVLGNVFGEASPVGEVRYEAPFYDYETKYTPGRAELLIPAPLDPGTQETVQELALKAYKVLGVRGMARVDFFLAEGELYLNELNTIPGFTPTSMYPRLFEAGGVAYPELLRRLVELALT
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LINX_SPHIU
Sequence: MANRLAGKVALITGGASGLGAAQAKRFAEEGAKVVIGDLNEEMAKGVVAEIRAAGGDALFIRLDVTDAASWNNAIAAAVEAFGGLTTLSNTAGIIHPGGFEEESIEGWNKMVAVNQTAIFLGIKAAIPELVKSGNGSIINISSLIGMFPTAGNASYCATKAAVRIMSKAAALEFVDRGVRVNTIVPGGMNTPITANVPPDVLKQQTSQIPMGKLGDPIDIANGALFLASDEAKYITGVDLPIDGGWSVGV
What is the function of this protein?
Catalyzes the degradation of 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) into 2,5-dichlorohydroquinone (2,5-DCHQ) in vitro.  LinX appears not to be involved in gamma-hexachlorocyclohexane (gamma-HCH) degradation pathway, in contrast to LinC which has the same enzymatic activity.
What are the official names of this protein?
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinX, 2,5-DDOL dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: Y6239_DICDI
Sequence: MNTNNNFSNGEEVSIHIGTGIDIAAKAWGPKESSQKMLALHGWLDNANTFDFIAPILAEKGIRIIAIDFIGHGLSPHKPSWCNLYYTDYITQVLDVAEALQWKTFSIMGHSMGAGIASIVAASMPHLVERIICLDFIGILSKEQDQIKAIQFAMQTRTTINNRKPHLYNNKQAIFDKLKANNPWIKDEAGQRLLDRSIESVISPTTGEQCYKLRHDPRLVGPSIFIMREAEVLLMLDEIQCPVLLIWGTTSSQQFQIKKNWTQIMEGRMSHIKNLKQLVVPGSHHFHMENTSAFSQDILEFMFEEKDLSFTPSSTTQQQQQQQQSAENKKGDNHNQIAEQDLSTSNTSSPIISKPKPNL
What is the function of this protein?
Probable serine hydrolase.
What are the official names of this protein?
Serine hydrolase-like protein DDB_G0286239.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.