PharMolix/UniProtQA huggingface dataset:
Protein: PG065_MONPV
Sequence: MEKREVNKALYDLQRSAMVYSSNDTPPRWSTTMDADTRPTDSDADAIIDDVSREKSMREDHKSFDDVIPVKKIIYWKGVNPVTVINEYCQITRRDWSFRIESVGPSNSPTFYACVDIDGRVFDKADGKSKRDAKNNAAKLAVDKLLSYVIIRF
What is the function of this protein?
RNA-binding protein that plays a role in the inhibition of multiple cellular antiviral responses activated by double-stranded RNA (dsRNA), such as inhibition of PKR activation, necroptosis, and IFN-mediated antiviral activities.  Recognizes and binds Z-RNA structures via its Z-binding domain and dsRNA via its DRBM domain: RNA-binding activity is required to escape host ZBP1-dependent necroptosis.  Mechanistically, the Z-binding domain binds Z-RNAs that are produced during vaccinia virus infection, thereby competing with Z-RNA detection by host ZBP1, suppressing ZBP1-dependent necroptosis.  Acts as a key inhibitor of the interferon response by blocking the phosphorylation and subsequent activation of IRF3 and IRF7 kinases that are required for interferon-alpha gene expression.  Inhibits NF-kappa-B activation and the ubiquitin-like protein ISG15, which is an early antiviral protein.  The binding with host ISG15 subsequently blocks host ISGylation.
What are the official names of this protein?
RNA-binding protein OPG065.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG065 family.
Protein: KAMA_FUSNN
Sequence: MNTVNTRKKFFPNVTDEEWNDWTWQVKNRLESVEDLKKYVDLSEEETEGVVRTLETLRMAITPYYFSLIDLNSDRCPIRKQAIPTIQEIHQSDADLLDPLHEDEDSPVPGLTHRYPDRVLLLITDMCSMYCRHCTRRRFAGSSDDAMPMDRIDKAIEYIAKTPQVRDVLLSGGDALLVSDKKLESIIQKLRAIPHVEIIRIGSRTPVVLPQRITPELCNMLKKYHPIWLNTHFNHPQEVTPEAKKACEMLADAGVPLGNQTVLLRGINDSVPVMKRLVHDLVMMRVRPYYIYQCDLSMGLEHFRTPVSKGIEIIEGLRGHTSGYAVPTFVVDAPGGGGKTPVMPQYVISQSPHRVVLRNFEGVITTYTEPENYTHEPCYDEEKFEKMYEISGVYMLDEGLKMSLEPSHLARHERNKKRAEAEGKK
What is the function of this protein?
Catalyzes the interconversion of L-alpha-lysine and L-beta-lysine.
What are the official names of this protein?
L-lysine 2,3-aminomutase, LAM, KAM.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. KamA family.
Protein: RK33_WHEAT
Sequence: MAKGKDVRIRVILECISCVRKGANEESTGISRYSTQKNRHNTPGQLEFKKFCRYCRKHTTHHEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSBM_SYNPW
Sequence: METNDLGFVASLLFVLVPTVFLIILFIQTNSKEG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: GLMU_MANSM
Sequence: MKKLSVVILAAGKGTRMYSDLPKVLHKIAGKPMVKHVIDTAKQLSADQIHLIYGHGADLLKSHLADEPVNWVFQAEQLGTGHAMQQAAPFFADDENILMLYGDSPLISKETLEKLIAAKPENGIALLTVNLDNPTGYGRIIREKGSVVAIVEQKDADAEQLKITEVNTGVMVSDGASFKKWLGRLNNNNAQGEYYMTDVIGLANQDGFQVAAVSATDKMEVEGANNRLQLAALERYYQHKQAERLLLEGVMLIDPARFDLRGTLEHGKDCEIDVNVIIEGSVKLGDRVKIGAGCVIKNCEIGDDVEIKPYSVFEDSTIGARASIGPFSRLRPGAELAEETHIGNFVEIKKATVGKGSKVNHLTYVGDAQVGTDCNLGAGVITCNYDGANKFKTVIGDNVFVGSDVQLVAPVNVANGATIGAGTTVTKDIGENELVISRVPQRHIAGWQRPTKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_PSEA6
Sequence: MSCEVLALTEELINRQSVTPEDAGCQQLMAEYLAPLGFDIESMVFDDTTNMWARKGTGGPVFCFAGHTDVVPSGPAEKWTFPPFTATQHEGQLYGRGAADMKGSLAAMLVATKAFVTKHPEHSGSIAFLITSDEEGPFINGTTRVIDTLEARNEKMTWCLVGEPSSTTLIGDVVKNGRRGSLTGDITVKGVQGHVAYPHLAKNPIHLSAPAFAELAQTHWDSGNASFPPTSFQVSNINSGTGAGNVIPGDLSACFNFRFSTEVTDKQLIERVTTILDKYDFDYHIDWTFNGQPFLTDSGKLVEATQSAIKDVTGRETELSTAGGTSDGRFIAPTGAQVIELGPINATIHKIDENVNINDLAQLAKIYEGILQRLLA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: QUEC_SALPA
Sequence: MKRAVVVFSGGQDSTTCLAQARHQYDEVHCVTFDYGQRHRAEIDVARALALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPNADGIPNTFVPGRNILFLTLVAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVNLGMAKDIRFETPLMWIDKAETWALADYWGQLDLVREETLTCYNGIKGDGCGHCAACNLRANGLNHYLSNKSAVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PAAF1_DICDI
Sequence: MTSNTTEIPYHFLPYVRIQYDWQLAYKQDSDNCWVAYQKDLKNTIHGSVHSTKIDENNFKFESDYGFKLTPNKENKNNIRVENDKYSIEIYAPEKQLKVSGGKKRITSMGVSHLGELGVYGSTDGTLEVFETGDGQIRRKLDGHVGDVDLAMFFPSGRVILSGSSDSRLKIWDAIEGTCASTLVGHIGGITSASLVDRGRNLVSCSRDGTSKLWDIPTSSIISNLTKLSRPINDSFIASSLLDSIPTTTTTNSNDNNKVDEREVGTDGKTLIIAAEEGFLQAIDLRSKNMISQMNVVQSGEKSTRSVAFNACHVHKNYIIGGDHNGSIYFWDKRNLNSPFCRLQFTNSPIHHIKANSSNSKIANSIWVTSGDGCCFLLDLDKNQIITSLSGIDTDVVTSFNIVGNQAYLTSRDSIIRCYNNLLNI
What is the function of this protein?
Inhibits proteasome 26S assembly and activity by impairing the association of the 19S regulatory complex with the 20S core.
What are the official names of this protein?
Probable proteasomal ATPase-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PAAF1/RPN14 family.
Protein: EFTS_BACAN
Sequence: MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDFLREKGIAKAAKKADRIAAEGLTFIETNGNDGLILELNSETDFVAKNEGFQTLIKELAAHLLANKPANVEEAMAQTMENGKKVEEHINEAIAKIGEKLTLRRFEIVSKTDADAFGAYLHMGGRIGVLTVLEGSTDEAAAKDVAMHIAAVNPKYIDRDAVTAEEVEHERQVLTQQALNEGKPEKIVAKMVEGRLGKFFEEICLLDQAFVKNPDMKVRQFVESKGGTLKGFVRYAVGEGIEKREDNFAEEVMNQVKGSN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE1_HPV48
Sequence: MADHKGTDNIDHNDVLDGSWCLITEAECEDDTLVDLFEESTNDSVVSNLLDDSESIIQGNSEESDRCIQELKRKLNVTPEKQISELSPRLSAVHITPERASKRRLFNDSGVVEDEAESNTIQVDSLLVQKDAGNQNGAECELNSILRSNNIRATVLCKFKDKFGVSFNELTRSFKSDKTCTPNWVITAIGIREDLRDACKVLLQQHVEFLEMICNDFSVLLLVEFKVTKNRETVLKLMCSMLNAKEEQILCEPPKLKSTAAALYFYKKIITDTCFKYGTLPSWVSRLTIVEHQLASADTFSLSEMVQWAYDNDFTEEASVAYNYACYATENTNAAAFLASNMQVKYVKDCVAMVRMYKRQEMKSMTMSEWISKCCKEETIGEEWKEIVQFLKYQGVNFLEFLIALKQFFKCTPKKMCIVIYGPPDTGKSMFCFKLVQFLKGQVVSYINKSSQFWLMPLQDAKIGLLDDATHNCWIYLDTYLRNAFDGNTFCLDIKHKNLQQTKLPPMIITTNVNVTTDESLFYLRSRLTCFNFPNKLPMSDKDEPLFTISDKSWTCFFRKFWNQLELQEDAARDPGEPEHPFCCTARNSVDFD
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GLYR1_DROPS
Sequence: MSKNKKMSLSGGDTTEKFIYKPKDLIWAKMKGFTPWPGMIVEPPLDLLTQQRRANTKCVFFFGSRNFAWIEENNIKPFEGPWKEELAKVSKPAAFRHAMADIDKYIDDPAEVDDQINESCGVPNHATEADFDKIRDAVDSDENAVDADADANNGVVVHVVGSPDVSEAVEGENNADSSASPTVTAATPATAKSPAKRTPKAKPVSAVSATKAAKASTTKSAQKRRISAHQTPTGANTSGLPNAKRGKRVVSGGATPGNFDGASSSSPTARRRVEVDDLLASLAAKRAPNAIALLDRPVVTRPETQAIDMNSRSNTLADRDIVPSELTFGFLGLGMMGSTIVKDLIYTGHKVVVWNRTIDKCQPFVEAGAEVKDTPMDVVEAADIIFCCVSDPKGAKDLVFGNCGVLQLKDLRNKAYVEMSTVDPDTSLDIGEGIKQCNGRYLEAQIHGSRQEAADGMLIILAGGDRTVFEECHSCFKTIAKNTFFLGNVGNACKVNLILQTIQAVSLVGLAEALALADRFSISLNDIIDIFDLTSMKSPLLLAKGKEMAKGDFNPQQPLSHMQRDLRLVLNMAENLDQSMPVTSITNEVFKHTKRLGYSEHDSSAVFVRSRF
What is the function of this protein?
Nucleosome-destabilizing factor that is recruited to genes during transcriptional activation and colocalizes with a subset of trimethylated 'Lys-36' histone H3 (H3K36me3)-enriched regions.  Binds DNA (in vitro).  Facilitates Pol II transcription through nucleosomes.  Facilitates male-specific lethal (MSL) histone acetyltransferase complex targeting to active genes on the X chromosome.  Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by nej (By similarity).
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, Glyoxylate reductase 1 homolog, Nuclear protein NP60 homolog, Putative oxidoreductase GLYR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Chromosome. Note=Localization to open chromatin depends on H3K36 trimethylation by Set2.
Protein: ML423_ARATH
Sequence: MGLSGVLHVEVEVKSPAEKFWVALGDGINLFPKAFPNDYKTIQVLAGDGNAPGSIRLITYGEGSPLVKISAERIEAVDLENKSMSYSIIGGEMLEYYKTFKGTITVIPKDGGSLLKWSGEFEKTAHEIDDPHVIKDFAVKNFKEIDEYLLKQTSA
What are the official names of this protein?
MLP-like protein 423.
What is the protein family that this protein belongs to?
Belongs to the MLP family.
Protein: Y075_NITWN
Sequence: MTPPHSDRPEDTADPKLLEILVCPVTKGPLELDGARRELISRSAKLAYPIRDGIPIMLPEEARKIE
What are the official names of this protein?
UPF0434 protein Nwi_0075.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: NDOR1_KLULA
Sequence: MQNKKIVILYGSETGNAQDFAHILSHKLKRLHFSHTLIKIGDYHPKSVLQCKYLFIICSTTGQGELPRNARENCNGRAQGTLWQFLKKSTLPADLLDHVNVAMLGLGDSSYPRFNFGIRKLHERIVNQLGASEIFPRLEADELGLAGSNKDTGNGVESVYYEFEKRIIAYMLEKYPNRKHDGKMMPRVGLAEDVYLKPSNILEISTVNGSTNDQLPDSKIQFVGDETIRHGTVKKNNQITAKDHFQDVRQFVFETEDHEAYHPGDTVSLYPENSDNDVELFLEAQPHWKKVADELLTITDLENCDRFRDGGVVKPLTLRTLLKYHFDIVSIPRQSFFMKTWTFANAHEDRPTDQELLEQQRDKLRQFGYGQDLQDLYDYCNRPRRSVLEVIQDFEFLKLPWEFALDYLPMIKPRFYSISSAPSDPNVELTIAIVRYKTLLRKVRKGLCTNYLLTLTENDTVRYKLQNNHLLHEDIIGKPIIMTSPGVGLAPMKCLIESNLFKDQYLFFGNRMKDKDFLYEDTLSMWKKEGKINLFTCFSRDPINSPHAKYVQDQLWNQSSLIADLILKKSAIVYICGSSGKMPVQVRLTIVEILKKHGNFENAEEAEHYLKEMERTDRYMQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: RUVC_AROAE
Sequence: MKSASTVVATRILGLDPGLRITGFGVIDKLGNQLRYVASGCIRTRDGELPGRLKTLLDGVREVVAAYTPDQVAVEKVFVNVNPQSTLLLGQARGAVICGAVSCDLPVHEYTALQVKQAVVGYGKAAKEQVQHMVQRLLALDGCPSPDAADALACAICHAHGGQGTAGAFAGRRRAGRILVAPDPG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NTE1_NEOFI
Sequence: MADGVTLVDSTGLHSFSSSPSLSTSSSSLTAVALSLATSASAVTASYSISHLPPPPLPPVPTTMAGWIGWVFSFFFQVIPSVLYWVITFSTITLPTWLFTLFSMSLTFTMNFTTLLLIVLAMVSTISWFIRYRFLNMYSRLPPEPQRKEPQVDLFPDVQEGDSKPGLANYLDEFLSAIKVFGYLERPVFHELTRTMQTRKLIAGETLMLEEEKGFCLVVDGLVQIFVKSMRDGKSDTDEELHHLGAESSDEEHHIDGKQGYQLLTEVKNGASMSSLFSILSLFTEDIQLRENESSGSSSSSIALRAARVPNSIPTSPRGVMDSPSLGFQDHSDDTSNMITNGDLPSVPPLHLGESHTPPSGDQHHQQHHESRKHSSRKRRKSVHPDIVARAMVDTTIAIIPASAFRRLTRVYPRATAHIVQVILTRLQRVTFATAHSYLGLSNEVLGIEKQMTKFTTYDLPNNMRGAALDRLKDKFIKERDRLGSEEVTKGIALHNPSAGRRRRSSSFLRKDAALQVKMMTPRRAATVVTPESAPAEHDTYGVSPGDLLSTIQSSRFGPRYEQPPAKLQSPLAEKENTHFRLPAMQARHTFRRQDTMDEDALFRECILDCIMKGIGLTSSTRDALRKSSHSGDASPKLLSYDSRRQKAIFTNNAFGFIDPYEGSGDGETESLMSMSVTSAGGTSPVINLREELRNDIEIVYFPKGSVLVEQGERHPGLYYVIDGFLDVGVPIVEKGEDLVGVSKPAASKESFPTLKRTTTANSIGAGGTAANDSRRRKQSRKSLYLIKPGGIQGYVGAVASYRSYTDVVAKTDVYVGFLPRASLERIAERYPIALLTLAKRLTSILPRLLLHIDFALEWLQVNAGQVIYHQGDESDAIYLVLNGRLRSVLESPGNKLAVIGEYGQGESVGELEVMTESTRPATLHAIRDTELAKFPRSLFNSLAQEHPGITIQVSKLIAQRMRDLVERPVTEKGVERSNAGGVQTATSTVNLRTVGILPVTAGVPVVEFGNRLLHALHQVGVTNGVTSLNQAAILNHLGRHAFSKMGKLKLSQYLADLEEKYGMVLYIADTNVSSPWTQTCITQADCILLVGLAESSPSIGEYERFLLGMKTTARKELVLLHSERYCPPGLTRRWLKNRVWINGGHHHIQMAFRLTAEPSHPETKRFGTVLKQRVQVLQAEIQKYTSRRIRQTPLYSAQSPFKGDFHRLARRLCGRAVGLVLGGGGARGIAHVGVIKALEEAGIPVDIIGGTSIGSFIGALYARDADVVPMYGRAKKFAGRMGSMWRFALDLTYPTVSYTTGHEFNRGIFKTFGDSQIEDFWLEFYCNTTNISKSRPEYHSSGYVWRYVRASMSLAGLIPPICDEGSMLLDGGYIDNLTVDHMKGLGADVIFAVDVGSIDDNTPQVYGDSLSGFWSVFNRWNPFSSCPNPPTLSEIQARLAYVSSIDNLERAKNIPGCLYMRPPIDGYGTLEFGKFDEIYQVGYAFGKQFLEKLKTEGSLPLPEETEEKKKLQRTMAPRRASI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase nte1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MT_POVM3
Sequence: MDRVLSRADKERLLELLKLPRQLWGDFGRMQQAYKQQSLLLHPDKGGSHALMQELNSLWGTFKTEVYNLRMNLGGTGFQVRRLHADGWNLSTKDTFGDRYYQRFCRMPLTCLVNVKYSSCSCILCLLRKQHRELKDKCDARCLVLGECFCLECYMQWFGTPTRDVLNLYADFIASMPIDWLDLDVHSVYNPKRRSEELRRAATVHYTMTTGHSAMEASTSQGNGMISSESGTPATSRRLRLPSLLSNPTYSVMRSHSYPPTRVLQQIHPHILLEEDEILVLLSPMTAYPRTPPELLYPESDQDQLEPLEEEEEEYMPMEDLYLDILPEEQVPQLIPPPIIPRAGLSPWEGLILRDLQRAHFDPILDASQRMRATHRAALRAHSMQRHLRRLGRTLLLVTFLAALLGICLMLFILIKRSRHF
What is the function of this protein?
Plays a role in transformation by modulating the activities of cellular proteins involved in control of cell proliferation and by acting as a functional homolog of an activated tyrosine kinase-associated growth-factor receptor.  Recruits upon association with host Ppp2/PP2A the Src tyrosine kinase components Src, Yes and Fyn, thereby activating their kinase activity.  Activation of Shc1, Pclg1 and p85 mediate signal transduction pathways leading to cell cycle progression and cell division.  MT also plays a role in regulation of early and late gene expression and in viral DNA replication.
What are the official names of this protein?
Middle T antigen, MT, MT-AG.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: RL18_SYNE7
Sequence: MKVSRRESTRRRHRRVRRTIVGTPARPRLSVFRSNNHIYAQVIDDAAGHTLAAASSLDPDLRQSLTSGGNQQASAAVGKLIAERAQAKGVTTVVFDRGGNLYHGRVKALAEAAREAGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: DTD_ECOSM
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y511_STAAN
Sequence: MKKIMITGALGQIGTELVVKCREIYGTDNVLATDIREPEADSPVQNGPFEILDVTDRDRMFELVRDFEADSLMHMAALLSATAEKNPILAWDLNMGGLMNALEAARTYNLHFFTPSSIGAFGDSTPKVNTPQVTIQQPTTMYGVNKVAGELLCQYYFKRFGVDTRSVRFPGLISHVKEPGGGTTDYAVEIYFKAVREGHYTSFIDKGTYMDMMYMDDAIEAIIKLMEADDAKLETRNGYNLSAMSFDPEMVKEAIQEYYPNFTLDYDVDPIRQGIANSWPDSIDTSCSRGEWGFDPKYDLASMTKLMLEAIEQKDTVKNNN
What are the official names of this protein?
Uncharacterized epimerase/dehydratase SA0511.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: ATPG_STACT
Sequence: MGSLKDIDSRIKSTKKMNQITKAMNMVASSKLNKAQRNSNQFKPYMDKLQNAITAVAGQTTSNHPMLVERPVKKRGYLVISSDRGLAGAYNANILRKVLQDIQERGENPSDYKLLVLGKVGIDFFKNRSIEVEYALPDVPDQPTFKSIEPVTKKAIDLYENGDIDELNIYYNKFINVLESKPTAKRVLPLSKEDASSGLGQMSSYEFEPDKESILNIILPQYVEGLIYGTILNAKASEHAMRMTAMKNASDNASDLIDDLSLQYNRARQAAITQQITEIVGGATALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1614_BRUA4
Sequence: MNISRMEQRVLHVLAQGGYIRHQREDGHICEIECFTREGYLLSDCTMAVFQQLRRKRLIESRMGSPYRISFKGRENVRAQLNNR
What are the official names of this protein?
UPF0386 protein Oant_1614.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: XYNB_ASPFN
Sequence: MVSFSSLLLAVSAVSGALAAPGDSTLVELAKRAITSSETGTNNGYYYSFWTNGGGDVEYTNGNGGQYSVKWTNCDNFVAGKGWNPGSAKTVTYSGEWESNSNSYVSLYGWTQNPLVEYYIVDKYGDYDPSTGATELGTVESDGGTYKIYKTTRENAPSIEGTSTFNQYWSVRQSGRVGGTITAQNHFDAWANVGLQLGTHNYMILATEGYKSSGSATITVE
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable endo-1,4-beta-xylanase B, Xylanase B, 1,4-beta-D-xylan xylanohydrolase B, Endo-1,4-beta-xylanase G1, Xylanase G1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YPHH_ECOLI
Sequence: MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDHTINLALAIHGQVDPVTGVSQTMPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVSTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSLYNFLNILNINQIWLYGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEAQLRQI
What are the official names of this protein?
Uncharacterized protein YphH.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: CYB_CTETU
Sequence: MTNTRKSHPLIKIVNHSFIDLPAPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYMHANGASMFFIFLYFHIGRGIYYGSYTFMDTWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDILGVLFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHSSKQRSMSFRPLSQCLMWMLVANLLILTWIGGQPVEHPFITIGQLASVIYFFTILILMPSTALMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL28_SALRD
Sequence: MARKDDVTGEGPVTGNSVSDSNQKTNRRFKRNLHEKRFYIPSEDRHVKLKVSSKTLKTINKKGIQAVLEEARKQGYDV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.