PharMolix/UniProtQA huggingface dataset:
Protein: PGS2_PANTR
Sequence: MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
What is the function of this protein?
May affect the rate of fibrils formation.
What are the official names of this protein?
Decorin, Bone proteoglycan II, PG-S2.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HTPG_CLOPS
Sequence: MEKREFKAESKRLLDIVINSIYTNREIFLRELISNASDAIDKVYYKTLGDSSLTFNKDDYYIKIKPNKEERTLTISDKGIGMTEKELDENLGVIAKSGSLQFKKENEIKDGFDIIGQFGVGFYSGFLVADKITVITKAFGADKAYKWESDGVDGYTISEAEKDSFGTDIILHLKANDEDENYDEFLEEYKLKSLIKKYSDFIRYPIKLDVTKSRVKEGTENEHEEYVEEETVNSMVPLWRRNKNELTDDDYNNFYVEKRFGFDKPLRHMHISVDGMISYNSILYIPENIPYDYYTKEYEKGLELYSNGVLIMEKCSELLPDYFGFVKGIVDSQDLSLNISREMLQHDRQLSRIAKNIKTKIKNELESMMKNDRESYEKFYKSFGRQLKYGVYDDFGMNKDELKDLLMFYSSKEKKMVSLAEYVERMAEDQKYIYYAVGESNERIEKMPQTEMVLDKGYEILYFTEDVDEFAIKMLMNYKEKEFKSVSSGDLGIESEEENKKENEENKGIFEAMKEALGEKISAVKASSRLKNYPVCLSSEGEVSIEMEKILSAMPNNQGVKAQKVLEVNTNHEVFNSLKDALENDRDKFNLYTKLLYNQALLVEGLSIEDPVDFTNDICKLMK
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_STAAB
Sequence: MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKR_HELPH
Sequence: MDTHNKGDSIIRFSVSLQQNLLDELDNRIIKNGYSSRSELVRDMIREKLVEDNWAEDNPNDESKIAVLVVIYDHHQRELNQRMIDIQHASGTHVLCTTHIHMDEHNCLETIILQGNSFEIQRLQLEIGGLRGVKFAKLTKAFSFEYDE
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: DOT1_CANAL
Sequence: MISGHLQTPDSSDHSGDEAKLTKPSGLESKTNELWSSDLEEELESRIMQPATFSSILKQFPSISEETIISKIMSNKNCDKNNWKKKIYCYRYFLQPSKEEPDVGNMKSLVEKLEKLKLKKWSASEIEQLFCNYLEDLTTSAVKVSIPGKTLDEVAAAVNNIHPRPRWTRKEIECLIKNENDFKKLEKDLFVRDLDSIKKKIRRDNLSIQNEIQDSEKKSPQSTDSNNKDSSRDLSRKERDQLKKLLSKPICFSELLAKFPGHSWEYIAREIIQLDSSEDNTIWLKKIYYYCVVYSISVDKEITKYIGGGNRIYEKVRSDWSKIKTLDFFKDWSLQEFERLYCFAFHDLTKSALTKNFPSKNLNDICKVVNISFPKVPYTDREMKYLERHLDTPMQTLENNLPFRSRGSIHKKLEALKALTETTEQKQPPTKTRPKNEEEKNVENAAYMKELIMFDLTLEAIENTFPSEPIEEIIKEIKNSEIFDPLSFTRGEKELMAKLVKKGNLIDDCFDYFPLREEEFIRSKYAEAEYVSGRKMKFNTPEERLAYEAKWTLFNMGKQEYGRGNRRSTKRYCEIDELSKLEQEASVKRSKKKIELTEEELEQRRKRSEHFRLCRLKKLEEKREKYRIEKAKRLEKIAAGLIKPSTSGYELKDIVTSAEYFQSIVGDKQKVQEGQKRKRIQTEYFAPEFIEKPKAVKLKTTKRQAEKNKIKKQLKREAQLKIKKKKTIAPKKGKRRVKTNNGIIEEIKDVYKLSSEPYVESEVEEEDEEEDYISPYDPPDIISDSQVKLNGRHLYISSFYKELPEIPELKFVSLPHMEMSGNDITVAKQIMTTANDDILYDDCLAYEIVAQHIKSYRDLPISFPPVLDPITHELNSANIVRIRFFLYPEHYESFMLASPKSNELDPVHEIAKLFMIQYSLYFSHSDTLKKIITEDYCHKLEHSVEENDFGEFMFVVDKWNQLVMKLSPNLASVQNILGLKEDINEAPRAYLNQQEVSIPTNSDLKIETFYDEIMYESASPLFNPINSNLEIDSESAPIPLGEVEIPNNVIEEINEKMPDNYIPDFFRRLKEKTEVSRYAMQQILLRVYSRVVSTDSRKLRSYKAFTAETYGELLPSFTSEVLEKLNLLPTQKFYDLGSGVGNTTFQAALEFGACSSGGCEIMEHASKLTELQAGLIQKHLAVLGLQKLNLDFALHESFVGNEKVRASCLDCDVLIINNYLFDGQLNDEVGKLLYGLRPGTKIVSLRNFISPRYRATFDTVFDFLSVEKHEMSDIMSVSWTANKVPYYISTVEETIPREYLSREETKETSGKSKSVSPVGEIENVAAAMMTPPTDSSESEIIKN
What is the function of this protein?
Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3.  This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks.  Nucleosomes are preferred as substrate compared to free histone.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-79 specific, Histone H3-K79 methyltransferase, H3-K79-HMTase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2836_NOSS1
Sequence: MKISVIISNYNYARYLSRAINSVLAQTHSDIEIVIVDDGSTDNSRDVITQLQEQAPDKIKPIFQANQGQGGAFNAGFAAATGEVVAFLDADDVWKPHKLQRIVEVFQTSDVVGVMHHLDIIDGNDKTIDQASTQGPKLSEDLASVILQTGNAWCFPPTSGLAYRREVLEKVFPIDPVKWRIWADGCIIYCTAFLGKIKTLQENLAYYRIHGANNHMSAASATSEQEAKSQAGIEMTNQYINDFLVRIGYGARVDLSRNLQYRRTKYYQRSQWDLREVWGISRLILGWPFYSGQERAYYLARFLFKSGKFLLRSDVHTESTTI
What are the official names of this protein?
Uncharacterized glycosyltransferase alr2836.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: UREF_BURP1
Sequence: MDTAELVALLHLASPALPIGAFSYSQGLEAALDAPLIRDADGARDWIASGLADVLAQGELPFLAHQLARWHAHDAAALADANDEFVASRESFELRRETEQMGWSLAQLCASLEWGDAARRATLASIPSVALPSAFAFAAAAHGATPDAALAAYAFGWVENQTAAAIKAVPLGQLAGQKIIVALREPIRDAVRRALATPPEAINTFAPQLGILSARHESQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_SULSY
Sequence: MSVEQRVKEIIADQLGVEMEKITPEARFVDDLGADSLDVVELIMAFEEEFGVEIPDEDAEKIATVKDVLDYIKSKQG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL_ALHV1
Sequence: MMWKWVTLLLFVLVCGDNPVNAAAHNPFVCCHQKNETAHTPPKKAWSLVNAILHSPSQCNHTNVALAYFNTTKGYKQVSCVNGFGLMSFCLALFDRLLTINVRVADQKFYDELLGYKRGFAAQFSKATTDSSGFKNNLELDLITTRHGRMASKTHVAGLTRSSASSQL
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH.
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: YCF2_JASNU
Sequence: MNEDTNKERGTIGTVQWRWGERLGEILREIKNSHYFFFFDSFFDSWTQFNSVRSFIPIFFHQERFLKLADPRIWSILLSRTQGSTQGSTSITIKGVILFKGVILFVVAALIYRINNRNMVESKTLYLRGLLPIPMNSIGPRNDTLEESVGSSNINRLIVSLLYLPKGKRISESSFLNPKESTFLNPKESTWVLPITKKSSMPWGSRWWRNWIGKKRDSSQLKGSSYQSRDHLDSISNEDSEYHNQREIPLPEERKIEEFLENPTRSVRSFFSDRWSELHLGSNPTERSTRDQKLLKKQQDLSFVPSRRSEKKEMVHIFKIITYLQNTVSIHPISSDPGCDRVPKDESDMDSSNKISFLNKNPFSEERFQEMANRFTLSITEPDLVYPKGSRFCNESIYRRIIKKWVPRGNVLENLKRTQIVVFVSNNIMEAVNQYRLIRNLIQIQYSTYGYIRNVLNRFFLMNRSDRNFEYGIQRDQIGKGTLNHRTLMKYMINQHLSNFFLKKSPFDSLIVIEKSKNRDPFAYRYKWSNGSKNFQEHLEHFLSEQKSRLEIAFDQFQRNYDKPLPLLLESIASIGLQIVHLKKWKPFLLDDHDTSRKMIDSFHTRNNRRKSFEKTDSYFSMIFDNQDNWLNPVKPFHRSSLISSFFKANRLRFWNNPHHFCFYSNTRFPFSVEKARISNYDFTYGQFLNILFIRNKIFSLCVGKKKHAFGGRDTISPIESQVSNIFIPNYFPSRTIYSIADISGTPLTEEEIVNLERTYCQPLSVSDRNLSDSEGKNLNQYLNFNSSMRLIPTEKDFPWKKPEKRKKRSQKRKKQSPCLPCLLCLCLKKGVEKGEMDRRDSAFSFLSDWKDLFQTYMPWFLTSTGYKHLNGIFLEPFSDLLPILTSSLSSCLSSSLSSSLSSSLSSSLSSLSSSLSSSLSSSLSSSLSSSLSSSLSSSLSSSLSSSLKFVSTFHDSMHEVGISWQILQIELQLRLFHLSHWKWAFQFQWDRLNKILNWINWISEISRKCMYSRLLLEATGMIHGKNESPLIPTHLRSVNVRELLYSILFLLLLAGYLVHTHLVFVSRAFSELQTEFKKLKPFLIPSSRMELEELLDAYPTSEPNPFEFELVKSIRSKKKYWNINLIDFIPHRITLSRKMSHLSHTSKELYSLIRKRENVNIKNANEDGKIDSWVVNSDLFVEEEFFHLLYDRTFMLTTKKSIDPILWSLTHSDHLSTHLSKNDSGYQMIEQPGAIYLRYLVDIHKKSLWNYEFNTSCLAEKRVFLAHYQTITYSQTSCGTNTFHFPSHGKPFSLRLLSPSRGVLVIGSIGTGRSYLVKHLATNSHLPFIRLAVSELLNNNPKFRWIEPEDSWPVFDDLLEHSAYYENRVGDGRDYIIDTIDASDDIDIDIVARGDIDFDKEEELLTRESDEEKKNPVRVQEKYRAEQFEEDLELAKIISPCIIWIPNIHDLNLRESTSLAAGLFVNKYSERCSTRDILVIASTHIPQKVDPSLISTNRLNRCIKVRRFFIPQKEKHVFTLLYTRGFHPHLEKNAFGSITLGSSAQDLRPLINDALLIGISQRKSIIDTNTIRCALHRETWEFQSHPKWVPNSQILFYQIGRAVVQKVLLSNCLSNYLIDPLSIYMKKRSFAGGTEGDSSLYKWYFELGTSLKLVTILLYLLSCSAGSVARDLCFLPGEDRIKLFENEMDSTLFHELLLILLEVLALESPLMGSSRTEKDCSQFDNDRVPFPFRPEPRKLLAIQRFLSEKEEWELAEGKEEGLLQPPQEIEGHIVSAPKIWRPWFCLLDGLDRPVEFLELGYPYCYGYRSFEGKQILFDKEDELEENDSEFLQSFIPRSSDEHGFFKLNQFIWDPPDPLFLLSTDEFPGSVFSYRELFADEELRITKTKLRTFRTRWLSKKAQKGRLELLINRQRWLRPNSDESEDSLYSQILSEIFEYLKNLFLSKRGLLDQTRKVLFRKRWVFPDEMHIFFM
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SELO_XANOM
Sequence: MTQLHFDNRLRQQLPGYQEEGARRREVRAAWSAVMPTPVAAPYLIAHSAEMAHVLGLDASEVASAAFAQVFGGNALYPGMQPWAVNYGGHQFGHWAGQLGDGRAISLGEAIGIDGGRYELQLKGAGPTPYSRGADGRAVLRSSIREFLCSESMHHLGVPTTRALSLVGTGDAVVRDMFYDGRPQREPGAIVCRVAPSFIRFGNFELPSARGDNALLRQWVDFTIARDFPELVGTAEALYADWFAQVCQRTAVMVAHWMRVGFVHGVMNTDNMSILGLTIDYGPYGWVDDYDPDWTPNTTDAQGRRYRFGTQPQVAYWNLGRLAQAMAPLFADQAPLQQGLNRFRDTYLACDRRDTAAKLGLAECRDEDLELIDALRALMRDAEMDMTLTFRGLIDLSPVHPDPAQLHDAFYDDHKRVASASQLQEWLQRYAARLQQDALSPDERRALMRLANPRYVLRNYLAQQAIDQAEQGDPSGVQELLEVMRRPYDDQSGRAAFAARRPEWARDRAGCSMLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ILVE_METTH
Sequence: MSCEASGKIWLNGEMVEWEEATVHVLSHVVHYGSSVFEGIRCYRNSKGSAIFRLREHVKRLFDSAKIYRMDIPYTQEQICDAIVETVRENGLEECYIRPVVFRGYGEMGVHPVNCPVDVAVAAWEWGAYLGAEALEVGVDAGVSTWRRMAPNTMPNMAKAGGNYLNSQLAKMEAVRHGYDEAIMLDYHGYISEGSGENIFLVSEGEIYTPPVSSSLLRGITRDSVIKIARTEGVTVHEEPITREMLYIADEAFFTGTAAEITPIRSVDGIEIGAGRRGPVTKLLQDEFFRIIRAETEDSFGWLTYI
What is the function of this protein?
Acts on leucine, isoleucine and valine.
What are the official names of this protein?
Putative branched-chain-amino-acid aminotransferase, BCAT, Transaminase B.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: RS13_DESHY
Sequence: MARIAGVDLPREKRVEVGLTYIYGIGLPTAQKILARTGVNPETRIRDLSEEEVNRLREVIDKEIKVEGDLRREVSLNIKRLMEIGCYRGLRHRRGLPVRGQRTKTNARTRKGPIKTVGAKRKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: AATC2_BOVIN
Sequence: MPTLSVFTDVPMAQKLEGSLLKTYKQDDNPNKMFLAYKVCMTSKGRPWVSSVVRKTRMQIAQDPSLNYEYTPVMGMKSFVQASLNLLFGKNSQVIVENRAGGVQTVGDSGAFQLGAQFLKSWCQSSQIVYIVSSQKEPHGLIFQDMGFTVYEHTFWDSAHLCLDPNMLLDVVKHAPHGCVFVIGSMGNCQLTPSQWTQLMTLMKSKEIFPFFDIPYQGLSTGDLEEDARFLHYFVSQGFEFFCSQSLSKNFGIYDEGVGTLVVVTLDNQLLLRVLSQLMNFARALWLNPPTTGARIITSVLCNPAMQGEWRQSLEGVVENVMMTKEKVKEKLRLLGTPGSWDHITEQKGSHSYLGLNSQQVEYLISEKHIYIPKNGRINFTCINSYNIDYITSSINEAVCFTKDSER
What are the official names of this protein?
Putative aspartate aminotransferase, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Transaminase A-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSRC2_MOUSE
Sequence: MIRTNFLLKQGRRHESKDKSSKRHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRDRKKSRSRSRDRKKSRSRSRDRKRRIRTRSRSRSRHRHRTRSRSRSRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEMAAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKALAETGIAVPSYYNPAAVNPMKFAEQEKKRKMLWQGKKEGDKSQSAEIWEKLNFGNKDQNVKFRKLMGIKSEDEAGCSSVDEESYKTLKQQEEVFRNLDAQYEMARSQTHTQRGMGLGFTSSMRGMDTV
What are the official names of this protein?
Arginine/serine-rich coiled-coil protein 2.
What is the protein family that this protein belongs to?
Belongs to the RSRC2 family.
Protein: GPX1_PONPY
Sequence: MCAARLVAAAAQSVYSFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA
What is the function of this protein?
Protects the hemoglobin in erythrocytes from oxidative breakdown.  In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism.
What are the official names of this protein?
Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BOMB_PELRI
Sequence: NLGKQWAVGHFM
What are the official names of this protein?
[Asn3,Lys6,Phe13]3-14-bombesin.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HRPA_ECOLI
Sequence: MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQAIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVDELSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVKPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYEQKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTEEGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG
What is the function of this protein?
Not yet known.
What are the official names of this protein?
ATP-dependent RNA helicase HrpA.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
Protein: PMM2_HUMAN
Sequence: MAAPGPALCLFDVDGTLTAPRQKITKEMDDFLQKLRQKIKIGVVGGSDFEKVQEQLGNDVVEKYDYVFPENGLVAYKDGKLLCRQNIQSHLGEALIQDLINYCLSYIAKIKLPKKRGTFIEFRNGMLNVSPIGRSCSQEERIEFYELDKKENIRQKFVADLRKEFAGKGLTFSIGGQISFDVFPDGWDKRYCLRHVENDGYKTIYFFGDKTMPGGNDHEIFTDPRTMGYSVTAPEDTRRICELLFS
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Phosphomannomutase 2, PMM 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_GEOKA
Sequence: MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDWLREKGIAKAAKKADRIAAEGMAYIAVEGNTAVILEVNSETDFVAKNEAFQTLVKELAAHLLKQKPASLDEALGQTMDNGSTVQDYINEAIAKIGEKITLRRFAVVNKADGETFGAYLHMGGRIGVLTLLAGNASEDVAKDVAMHIAALHPKYVSRDDVPQEEIAHEREVLKQQALNEGKPEKIVEKMVEGRLNKFYEDVCLLEQAFVKNPDVTVRQYVESNGATVKQFIRYEVGEGLEKRQDNFAEEVMSQVRKQ
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity).
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIOC_ECOLI
Sequence: MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDLPASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAIDKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWVNLLK
What is the function of this protein?
Probable electron transporter required for biotin synthase activity.
What are the official names of this protein?
Protein MioC.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family. MioC subfamily.
Protein: HOLB_BUCAP
Sequence: MKWYPWLIKPYKKIIRLHERKKAHHAILIKTQKGMGVFKLVWFISKWLLCLKPKGTNFCDNCHGCKLMSANNHPDWHTIINEKNDVFDVDSIRVINEKIFKRAQQGNNKIIFLPNVHKLTESAVNALLKILEEPPEKNWFFLIDYNYLKLHSTLKSRCFLYRLPLPLEKESLNWLKNNNKKDNISNLTSLRINQDSPISAKNFIESDLWDERKNLYKSLSHSIKDKNLLKILPVLCKKNTIMKIDWICLLLFDAVKTNFNERKKLINCDQIKLINFFSKKYNNILLNKSIRKWTKCRYILSSVSSINSELLLLEQLLLWEKILCFITP
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity).
What are the official names of this protein?
DNA polymerase III subunit delta'.
Protein: REN3A_DANRE
Sequence: MRSEKEQRTGSRERGSVEIQFRDCQDNAAVNPKHKEEKKEIFSKVVIRRLPPSLSKDQLQEHLSPLPSFDYFEFFPADQSLYPHLFSRAYINFKNPEDIIIFRDRFDGYVFIDNKGQEYPAVVEFAPFQKVSKKKLKKKDAKAGTIEEDPEYRRFLENYSCDEEKSMANPETLLGEIEAKTRELIAKRTTPLLEYIKNKKLEKQRIREEKREERRRRELEKKRQREEEKRKRREEERQKRKEAEKQKKLSEKEIKIKLLKKCDRDDDVDSDRLKDKGDSGETEKNRWEKPGGHTKSKDSKDNRSQMENDKEQREGHGRRQRDKDHRGRDEERKRQRHHYEFDKFMRRKEETKWGKGYCQDRAKKDQHHGYSYCPETGDKLGKEDREDMGSRKERIRNKDRPAMQLYQPGARNRKRMGSGNKTFDFPPISPEHAGEHCYKTVIGTGSEKSADE
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery.  Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD.  Binds spliced mRNA upstream of exon-exon junctions (By similarity).
What are the official names of this protein?
Regulator of nonsense transcripts 3A, Up-frameshift suppressor 3 homolog A.
What is the protein family that this protein belongs to?
Belongs to the RENT3 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttling between the nucleus and the cytoplasm.
Protein: MSRA_STRAW
Sequence: MAAQTQRAVLAGGCFWGMEDLIRRLPGVTATRVGYTGGDVPNATYRNHGTHAEAIEILFDPARTDFRAILEFFFQIHDPSTKNRQGNDIGLSYRSAIYYVDDEQKRIAEDTIADVDASGLWPGKVVTEVEPVGPFWEAEPEHQDYLERYPDGYTCHFPRPGWRLPARAEG
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CSK_MOUSE
Sequence: MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTTDADGLCTRLIKPKVMEGTVAAQDEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMKNCWHLDAATRPTFLQLREQLEHIKTHELHL
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response.  Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN, CSK or YES1.  Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation.  To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane.  Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase MPK-2, p50CSK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Mainly cytoplasmic, also present in lipid rafts.
Protein: YEIH_SHIFL
Sequence: MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGFSALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGISGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEASKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAISPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEKSKITIPWFAILFIVVAIFNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLIVGGGAINYVIQSVIA
What are the official names of this protein?
UPF0324 membrane protein YeiH.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3869_BACTN
Sequence: MLVLLSCAKTMSAVSKVKVPLTTSPRFQKEAAEIALQMSQFSVDELERLLRVNAKIAVENYKRYQAFHAETTPELPALLAYTGIVFKRLNPKDFSAEDFGYAQEHLRLTSFCYGLLRPLDVIRAYRLEGDVVLPELGNQTLFSYWRSRLTDTFIEDIRSAGGILCNLASDEMKSLFDWKRVESEVRVVTPEFHVWKNGKLATIVVYTKMSRGEMTRFILKNKIGTPEELKGFSWEGFEFDESLSDERKLVFINGMGE
What are the official names of this protein?
UPF0246 protein BT_3869.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.