PharMolix/UniProtQA huggingface dataset:
Protein: ACCA_THET2
Sequence: MKSPFWSWNGRIAELKETAKATGVDLEAEIRLLEERLARLRKETYENLTPWQRVQLARAPGRPTTLDVLEKAFQDFIELHGDRAFADDPAIVGGLAYLEGEKVVVVGHQKGRDTKENLQRNFGMPHPEGYRKAMRLMDLADRFGYPFLTFVDTPGAYPGVSAEERGQAWVIAQSIQRMSRLRVPAVTVILGEGGSGGALAIAVANRVLILENAWYSVISPESCAAILWRDAKEAPKAAEALKLTAKDLLQLKVVDAIVPEPEGGAHKDPDRAIRNIKEALLKALEELKGLSPEALYEDRYRRFRSLGAFAEP
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTM_MYCTO
Sequence: MSTVLTYIRAVDIYEHMTESLDLEFESAYRGESVAFGEGVRPPWSIGEPQPELAALIVQGKFRGDVLDVGCGEAAISLALAERGHTTVGLDLSPAAVELARHEAAKRGLANASFEVADASSFTGYDGRFDTIVDSTLFHSMPVESREGYLQSIVRAAAPGASYFVLVFDRAAIPEGPINAVTEDELRAAVSKYWIIDEIKPARLYARFPAGFAGMPALLDIREEPNGLQSIGGWLLSAHLG
What is the function of this protein?
Involved in cellular response to chemical stress and may contribute to resistance toward antimicrobial natural compounds as well as drugs.  Catalyzes the methylation and detoxification of the P. aeruginosa toxin 2-heptyl-1-hydroxy-4(1H)-quinolinone (HQNO) to 2-heptyl-1-methoxy-4(1H)-quinolinone (HMOQ).
What are the official names of this protein?
2-heptyl-1-hydroxyquinolin-4(1H)-one methyltransferase, HQNO methyltransferase, HQNO-MTase, Heterocyclic toxin methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF1A_SOLLC
Sequence: MMERFPRLAQRVLSVPFTPKYLKSCKKTNPLTSHLMQLRGSQRPIFIQWNLQGRPSVCTDLISKKNYSSATARAGWFLGLGEKKKQAMPDIVKAGDPVLHEPSQDIPLEEIGSERIQKIIEEMVKVMRNAPGVGLAAPQIGIPLKIIVLEDTNEYISYAPKDETKAQDRRPFGLLVIINPKLKKKGNKTALFFEGCLSVDGFRAVVERHLEVEVTGLDRNGKAIKVDASGWQARILQHEYDHLDGTLYVDKMAPRTFRTVENLDLPLAAGCPKLGVC
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.
What are the official names of this protein?
Peptide deformylase 1A, chloroplastic, PDF 1A, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ARNF_ECOHS
Sequence: MGLIWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPMTKQRY
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF, L-Ara4N-phosphoundecaprenol flippase subunit ArnF, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF.
What is the protein family that this protein belongs to?
Belongs to the ArnF family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MATK_SPAJU
Sequence: MEEYQVYLELDISRQQHFLYPLIFREYIYGLAYGHYFNGSIFSENVDYDNKSSLLIVKRLITRMSQQNHLIISANDSKKNQFWGYNKNLYSQIISEGFAIVVEIPLSLQLNSSSEEAEIIKYYKNLRSIHSIFPFFEDKLTYLNYVSDARIPYPIHLEILVQVFRYWAKDAPLFHLLRLFLYEYWNWNNLITPKKLISTFSKSHLRVFLFLYNFYVCEYESIFLFLRNKSSHLRLTSFSLLFERIYFYGKIEHFVEVFVKDFSSTLSFFKEPFIHYVRYQGKSILASKNASLLMNKWKNYLIRLWQYHFDVWSQPRTIQLNQFSERSFHLLGYFSNVRLNLSAIRSQMLENAFLIKIVMKKLETIVPIIPLIRSLAKAKFCNVLGHPISKPLWADSSDFDIIDRFLRICRNLSHYYNGSSKKKSLYRVKYIFRLSCIKTLARKHKSTVRAFLKRLGSEKLLEEFFTEEEEILSLVFQRASSTLQGLYRGRIWYLDIIFSNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYT_BITAR
Sequence: IPGGLSPRDVTDPDVQEAAAFAVEKYNAGSKNDYYFKERRVVEAQSQVVSGVKYYLMMELLKTTCKKTVGRPKGYQEIQNCNLPPENQQEEITCRFEVWSRPWLPSTSLTK
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR12_PHATC
Sequence: MPTIQQLVRSRRIQIKKKTKSPALVNCPQRRGVCTRVYTTTPKKPNSAIRKVARVRLTSGFEVTAYIPGVGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGALDTGGVKGRTQGRSKYGVKKPKAEK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IST3_YEAST
Sequence: MNKIQQINDKELQSGILSPHQSWHNEYKDNAYIYIGNLNRELTEGDILTVFSEYGVPVDVILSRDENTGESQGFAYLKYEDQRSTILAVDNLNGFKIGGRALKIDHTFYRPKRSLQKYYEAVKEELDRDIVSKNNAEKLILAKKDQPN
What is the function of this protein?
Required for pre-mRNA splicing and spliceosome assembly.  As part of the pre-mRNA retention and splicing (RES) complex, required for nuclear pre-mRNA retention and efficient splicing.  Required for MER1-activated splicing.
What are the official names of this protein?
U2 snRNP component IST3, Increased sodium tolerance protein 3, U2 snRNP protein SNU17.
What is the protein family that this protein belongs to?
Belongs to the IST3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIMP_CLOPS
Sequence: MKKEQLVADLEALCAPIVKEKGYDLYHIEYVKENNEYYLRLYIEKPEERISLRDCEIVSRALSDMLDIEDPIKDAYFLEVSSPGLNRRLHSDEHFNRFIGKEIFVGFKSSLSGRKNVKGILKDVQENEIIVECEGNEIKVPKDKIKTANLEGEI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALF_SHIFL
Sequence: MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQRVKRQLLAEVQSICPPGVIIMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRSQVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKGIEKLLSE
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: VE5_HPV16
Sequence: MTNLDTASTTLLACFLLCFCVLLCVCLLIRPLLLSVSTYTSLIILVLLLWITAASAFRCFIVYIIFVYIPLFLIHTHARFLIT
What is the function of this protein?
Acts to keep host cells in a proliferation-competent state upon differentiation.  Enhances host epidermal growth factor receptor (EGFR) activation after stimulation by EGF by inhibiting EGFR internalization.  Induces a redistribution of host caveolin-1 and glycosphingolipid (ganglioside GM1) components of lipid rafts to the plasma membrane.  Since GM1s inhibit cytotoxic T-lymphocytes, block immune synapse formation, and enhance proliferative signaling by the EGFR, E5 may enhance immune evasion and cell proliferation via a common mechanism.  E5 also alters endosomal pH by interacting with the vacuolar H+-ATPase, which is a proton pump responsible for acidifying cellular organelles.  Additionally, E5 prevents transport of the major histocompatibility class I to the cell surface and retains the complex in the Golgi apparatus.
What are the official names of this protein?
Probable protein E5.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E5 protein family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein. Host endoplasmic reticulum membrane. Host Golgi apparatus.
Protein: HQGT_RAUSE
Sequence: MEHTPHIAMVPTPGMGHLIPLVEFAKRLVLRHNFGVTFIIPTDGPLPKAQKSFLDALPAGVNYVLLPPVSFDDLPADVRIETRICLTITRSLPFVRDAVKTLLATTKLAALVVDLFGTDAFDVAIEFKVSPYIFYPTTAMCLSLFFHLPKLDQMVSCEYRDVPEPLQIPGCIPIHGKDFLDPAQDRKNDAYKCLLHQAKRYRLAEGIMVNTFNDLEPGPLKALQEEDQGKPPVYPIGPLIRADSSSKVDDCECLKWLDDQPRGSVLFISFGSGGAVSHNQFIELALGLEMSEQRFLWVVRSPNDKIANATYFSIQNQNDALAYLPEGFLERTKGRCLLVPSWAPQTEILSHGSTGGFLTHCGWNSILESVVNGVPLIAWPLYAEQKMNAVMLTEGLKVALRPKAGENGLIGRVEIANAVKGLMEGEEGKKFRSTMKDLKDAASRALSDDGSSTKALAELACKWENKISST
What is the function of this protein?
Broad spectrum multifunctional glucosyltransferase.  In addition to hydroquinone it accepts at least 45 natural and synthetic phenols as well as two cinnamyl alcohols as substrates.  Hydroquinone was however the best substrate.  In contrast to this broad acceptor substrate specificity, only pyrimidine nucleotide activated glucose is tolerated as a donor substrate.
What are the official names of this protein?
Hydroquinone glucosyltransferase, Arbutin synthase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: COW1_CONTE
Sequence: MGKLTILVLVAVALLSTQVMVQGDGDQPADRDAVPRDDNPGGMSEKFLNALQRRGCPWQPYCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Contryphan-Tx.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.
Protein: XPT_DEIGD
Sequence: MQALVEAIRERGMILPGGMLKVDGLINHQLLPQLTREMGERFAAGFAPLNPNKVVTIEVSGIAPALATALALNVPLVYARKKKPITMQEPTFTAQSISRTKGGAVDLFVSSEYLGSGDRVVVIDDFLASGGTLRALAGIIALSGAELLGLGCVIEKGFEEGRAKLADLGVPILTLANILRMNEQEGIVVEAGLQDLPKQPAG
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_CORJK
Sequence: MLDVNFFDELRIGLATADDIRRWSRGEVKKPETINYRTLKPEKDGLFCERIFGPTRDWECGCGKYKRVRYKGIICERCGVEVTKSKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKIIYFAANIITSVDEEGRHNDQSTLEAEMLLEKKEVEQERDAELADRAKTLEDDLAELEAAGAKNDAKKKVQNAADREMRHIRERAEREIDRLDEIWNTFVKLAPKQMIVDENIYNELVDRYEDYFTGGMGAEAIQTLIRSFDLEAEAESLREVIRDGKGQKKLRALKRLKVVAAFLRSGNDPAGMVLDCIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRMLDLGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIIVGPQLKLHQCGLPKLMALELFKPFVMKRLVEKSYAQNIKSAKRMVERQRPEVWDVLEEAIAEHPVMLNRAPTLHRLGIQAFEPILVEGKAIQLHPLACEAFNADFDGDQMAVHLPLSAEAQAEARILMLASNNILSPASGKPLAMPRLDMVTGLYYLTLLKKPEEFGGQGAYAPATEDGPAQGVYSSLAEAIMAYDRGVLGLQAPIHVRISHLRPTAEIEAELFPDGWQRGQTWLAETTLGRVLFNELLPWNYPYVEGVMAKKPQASVINDLAAKYPMITVAQTVDKLKDAGFYWATRSGVTITMHDVLVLPNKQEVLDNYEAKARVIEKKMARGKINEAERYQSLVDLWKEATDYVGQSVEDLYPDDNPIPMIVKSGAAGNMRQIWTLAGMKGMVTNSRGEYITRPIKTSFREGLSVLEYFNNSHGSRKGLADTALRTADSGYLTRRLVDVAQDVIVREDDCGTKQGAVVPVAVPVLDAEGKPTGNYTAADFVETSVLGRYLASDATASDGTVIVAEGDVVGEGELQALLEAGVEEVKVRSVMTCATNTGVCSTCYGRSMATGKKVEIGEAVGIVAAQSIGEPGTQLTMRTFHLGGVGGDITGGLPRVQELFEARVPKAKSPIASVDGKVRIEDDDNFFTLTIEPDDGSDDVVYEKLSKRQGLATLGTGGVERPIRDGDHVKMGQQLLKGAADPHEVLRVMGRRGVQQHLINEVQKVYRDQGVAIHDKHIEIIVRQMLRRVTVIDSGSTEFLPGSLVDHADAVAASKEAVKTGGRPVEVRAEIMGITKASLATESWLSAASFQETTRVLTDAAINKRSDKLIGLKENVIIGKLIPAGTGISRYRNISVEPTEEARAAAYSLPSSFGDGFYADDTYGEFTGAAVPLDDIDLM
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: IF2_STRPB
Sequence: MSKKRLHEIAKEIGKSSKEVVEHAKYLGLDVKSHASSVEEADAKKIISSFSKASKPDVTASQTVKPKEVAQPSVTVVKETGSEHVEKTQVSKPKSRNFKAEREARAKEQAARKQANGSSHRSQERRGGYRQPNNHQTNEQGDKRITHRSQGDTNDKRIERKASNVSPRHDNHQLVGDRNRSFAKENHKNGRFTNQKKQGRQEPQSKSPKIDFKARAAALKAEQNAEYSRQSETRFRAQQEAKRLAELARQEAKEAALKAQAEEMSHREAALKSIEEAETKLKSSNISAKSTADNRRKKQARPEKNRELTHHSQEGQKKNKKSWNSQNQVRNQKNSNWNKNKKTKKGKNVKNTNTAPKPVTERKFHELPKEFEYTEGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDDADIERFFEDENYLNPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAINKIDKPGANPERVIAELAEYGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEELKADPTVRAIGTVIEARLDKGKGAIATLLVQQGTLHVQDPIVVGNTFGRVRAMVNDLGRRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERSKRALLKQRQNTQRVSLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLVKIEVEGVRVNVVHSAVGAINESDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDPVYQEKILGEAIIRETFKVSKVGTIGGFMVINGKVTRDSSVRVIRDSVVIFDGKLASLKHYKDDVKEVGNAQEGGLMIENFNDLKVDDTIEAYIMEEIVRK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM40L_BOVIN
Sequence: MGNTLGLAPMGALPRRSPRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHAAYAGDWQLSPTEVFPTVVGDMDSGGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIVVAHFLQSLTHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHRANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQANMVFRGLVDSNWCVGAVLEKKMPPLPVTLALGAFLNHWRNRFHCGFSITVG
What is the function of this protein?
Potential channel-forming protein implicated in import of protein precursors into mitochondria.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM40B, Protein TOMM40-like.
What is the protein family that this protein belongs to?
Belongs to the Tom40 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: YIBL_ECOL6
Sequence: MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKATLEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTALGREMGLQEMTGFSKTAF
What are the official names of this protein?
Uncharacterized protein YibL.
Protein: RL16_ACHLA
Sequence: MLMPKRTKYR
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y498_METJA
Sequence: MMKKTKVIVLAENALTTPGKLVRYINTLNQPVIVKETCFGAYIEGEEELVDKLAQEIRNYERNRIFCKDRGYAIWDKRRCRAFRGGGPREGFHQLEAEQAVLDKIGLALDKIDKEGIKPMEEVLAKENELIKRETKIPVEEFKNIIEKVLGSKNEA
What are the official names of this protein?
Uncharacterized protein MJ0498.
Protein: MTTB_METBF
Sequence: MAKNNAVAGFNALNGVELNLFTTDELKAIHYATMEVLMDPGIQVSDPEARQIFKENGCEVDEKTNVVKIPEYLVRKALQLAPSRFILWGRDKKFNTVQECGGKVHWTCFGTGVKMCKYQDGKYVTVDSVEKDIADIAKLCDWAENIDYFSLPVSARDIAGQGAQDVHETLTPIANTAKHFHHIDPVGENVEYYRDIVKAYYGGDEEEARKKPIFSMLLCPTSPLELSVNACQVIIKGARYGIPVNVLSMAMSGGSSPVYLAGTLVTHNAEVLSGIVLAQLTVPGAKVWYGSSTTTFDLKKGTAPVGSPELGLISAAVAKLAQFYGLPSYVAGSOSDAKVPDDQAGHEKTMTTLLPALSGANTIYGAGMLELGMTFSMEQLVIDNDIFSMVKKAMKGIPVSEETLAVESIQKVGIGNNFLALKQTRQLVDYPSNPMLLDRHMFGDWAAAGSKDLATVAHEKVEDVLKNHQVTPIDADILKDMQAIVDKADKAFRGM
What is the function of this protein?
Catalyzes the transfer of a methyl group from trimethylamine to the corrinoid cofactor of MttC.
What are the official names of this protein?
Trimethylamine methyltransferase MttB, TMA methyltransferase, Trimethylamine--corrinoid protein methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the trimethylamine methyltransferase family.
Protein: RSMH_OPITP
Sequence: MTPGHQPVLLREVLGFLAPRARGRYLDCTFGGGGHTRALLEAAAEVRVVALDRDPAAQPRAAALRETFGERFEFIDRDFGRLAELPHEGFDGVLFDFGVSSFQLDETERGFSFRHDAPADMRMDPRSGVPASQWLETATEEMLVRAIRDFGEEQHWRRIVRAIRDARGTGALARTASLAELIAAAIPACDRHAAKIHPATRAFQGVRIAVNDEIGAIERALPAAFAKLAPGGVLCVISFHSLEDRPAKQFFRRMCGQPESAADATPQDLRVKLADPLTRRPVTPADDELAANPRSRSAKLRALRRL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM3_VZVD
Sequence: MSLIMFGRTLGEESVRYFERLKRRRDERFGTLESPTPCSTRQGSLGNATQIPFLNFAIDVTRRHQAVIPGIGTLHNCCEYIPLFSATARRAMFGAFLSSTGYNCTPNVVLKPWRYSVNANVSPELKKAVSSVQFYEYSPEEAAPHRNAYSGVMNTFRAFSLSDSFCQLSTFTQRFSYLVETSFESIEECGSHGKRAKVDVPIYGRYKGTLELFQKMILMHTTHFISSVLLGDHADRVDCFLRTVFNTPSVSDSVLEHFKQKSTVFLVPRRHGKTWFLVPLIALVMATFRGIKVGYTAHIRKATEPVFEGIKSRLEQWFGANYVDHVKGESITFSFTDGSYSTAVFASSHNTNGIRGQDFNLLFVDEANFIRPDAVQTIVGFLNQTNCKIIFVSSTNTGKASTSFLYNLRGSSDQLLNVVTYVCDDHMPRVLAHSDVTACSCYVLNKPVFITMDGAMRRTADLFMADSFVQEIVGGRKQNSGGVGFDRPLFTKTARERFILYRPSTVANCAILSSVLYVYVDPAFTSNTRASGTGVAIVGRYKSDWIIFGLEHFFLRALTGTSSSEIGRCVTQCLGHILALHPNTFTNVHVSIEGNSSQDSAVAISLAIAQQFAVLEKGNVLSSAPVLLFYHSIPPGCSVAYPFFLLQKQKTPAVDYFVKRFNSGNIIASQELVSLTVKLGVDPVEYLCKQLDNLTEVIKGGMGNLDTKTYTGKGTTGTMSDDLMVALIMSVYIGSSCIPDSVFMPIK
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: MPPB_PONAB
Sequence: MAAAAARVVLLPAARRRLWGFSESLLIRGAAGRSSYFGENRLRSTQAATQVVLNVPETRVTCLESGLRVASEDSGLSTCTVGLWIDAGSRYENEKNNGTAHFLEHMAFKGTKKRSQLDLELEIENMGAHLNAYTSREQTVYYAKAFSKDLPRAVEILADIIQNSTLGEAEIERERGVILREMQEVETNLQEVVFDYLHATAYQNTALGRTILGPTENIKSISRKDLVDYITTHYKGPRIVLAAAGGVSHDELLDLAKFHFGDSLCTHKGEIPALPPCKFTGSEIRVRDDKMPLAHLAIAVEAVGWAHPDTICLMVANTLIGNWDRSFGGGMNLSSKLAQLTCHGNLCHSFQSFNTSYTDTGLWGLYMVCEPSTVADMLHVVQKEWMRLCTSVTESEVARARNLLKTNMLLQLDGSTPICEDIGRQMLCYNRRIPIPELEARIDAVNAETIREVCTKYIYNRSPAIAAVGPIEQLPDFKQICSNMCWLRD
What is the function of this protein?
Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (By similarity).  Preferentially, cleaves after an arginine at position P2 (By similarity).  Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis (By similarity).
What are the official names of this protein?
Mitochondrial-processing peptidase subunit beta, Beta-MPP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DAN_DROME
Sequence: MNIRMGTKGKRPLRSLTPRDKIHAIQRIHDGESKASVARDIGVPESTLRGWCKNEDKLRFMSRQSATDNLCADALGDKMDGGGGGGGGAGGGGLLGPPEKRQRLDGALPLNFSNKLKFDELAFKRSPLNGLDYSTNKNLADLGYNGLPVDYAAFNGGVKAKVFGADINRPAADPSLNAISPLSSLTHLSGLTGISQSPLAISFNELTTNLNLLAQLNPGLAAMSGLNSFPAGAGNLRTPKPSGQTPLQVQSPRSDSGDRSAQGLSVKNWAKQKPGEGQGSLNLSIKNEGKGGDIKSPSPSIAPSQMGGPMTLSNLAEDPLLYWLKSQQTMLGLNPLYPPTIPMGVTSPPIRSSTPQHMSQLAQTPPIPSAPLTPSSTPSGSLDEKNAAWYNWCKAFGASLHTLNPNAATLAALQANQLQQQVATTAAEGGSMGDPSNILYSHLTKETETPSVRSLSSNEQNPEADEATETDLDGEVEPEASGKPEDLSAAGKVMTPSQSPIAHSSGSRSPEPKAKTKTPETTNSTSECKKILDNMLFKMGGMEATGPLMPEQGSSESEGSFQDTSNPHTNNNDVSASNNNNNNNSNKTDEEEKAKYLDCTADEDIEAIRHGEKFLQWLENCSNPRVTAVQLMQLRFLIAAIKSGNETPMIEKSALPEDSEEHAAEEEGSGRGKSRRRK
What is the function of this protein?
Probable transcription factor with a role in the retinal determination (RD) network.  Regulates ato expression and is required for normal R8 induction and differentiation.  Danr appears to repress Dan expression, but Dan is required for Danr expression anterior to the morphogenetic furrow (MF).  Dan and Danr lie downstream of so and require dac function for highest levels of expression.  Contributes to differentiation of antenna-specific characteristics; effector gene that acts downstream of homothorax (hth), Distal-less (Dll), cut (ct) and spineless (ss) genes to control differentiation of distal antennal structures.
What are the official names of this protein?
Protein distal antenna.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPB3_HUMAN
Sequence: MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP
What is the function of this protein?
May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells.  Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).
What are the official names of this protein?
Serpin B3, Protein T4-A, Squamous cell carcinoma antigen 1, SCCA-1.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Seems to also be secreted in plasma by cancerous cells but at a low level.