PharMolix/UniProtQA huggingface dataset:
Protein: GLPF4_LACPL
Sequence: MIHQLLAEFMGTALMIIFGVGVHCSEVLKGTKYRGSGHIFAITTWGFGITIALFIFGNVCINPAMVLAQCILGNLSWSLFIPYSVAEVLGGVVGAVIVWIMYADHFAASADEISPITIRNLFSTAPAVRNLPRNFFVEFFDTFIFISGILAISEVKTPGIVPIGVGLLVWAIGMGLGGPTGFAMNLARDMGPRIAHAILPIKNKADSDWQYGIIVPGIAPFVGAACAALFMHGFFGIG
What is the function of this protein?
Transporter that facilitates the transmembrane diffusion of water, dihydroxyacetone, glycerol, urea, H(2)O(2) and D/L-lactic acid.  Is involved in the cellular racemization of lactate and lactate metabolism, but has likely a more general physiological role.  The transported molecule is indeed lactic acid and not the lactate anion, in agreement with the assumption that, with very few exceptions, MIPs (major intrinsic proteins) only facilitate the transport of uncharged solutes.
What are the official names of this protein?
Glycerol uptake facilitator protein 4, D/L-lactic acid transporter, Lactic acid channel.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NTF2_CANGA
Sequence: MSMDFNALAQQFTEFYYNQFDSDRSQLGNLYRDESMLTFETSQLQGAKSIVEKLVSLPFQKVAHRITTLDAQPASPNGDVLVMITGDLLIDDEQNPQRFSQVFHLIPDGNSYYVFNDIFRLNYSA
What is the function of this protein?
Facilitates protein transport into the nucleus.  Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import (By similarity).
What are the official names of this protein?
Nuclear transport factor 2, NTF-2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_FRAT1
Sequence: MSKYTILDKINTPSDLKLIPESQLKILSAELRAFLVDTLDVSGGHFASSLGATELTVALHYVYNAPYDNIVWDVGHQTYIHKILTGRKDKLVTIKKDGGISGFPKRSESEYDTFGVGHSSTSISAALGMAIADRLQGKSSNTVAVIGDGAITGGMAFEALNHAGGIKEDILVILNDNEMSISDNVGGLSAHFSKIISGGFYNSIREKGKEVLKNIPPIFEFVKKVETQTKGMFVPANFFEDLGFYYVGPIDGHDVTELVKTLRILKDHKGPKLLHVITKKGKGYTKAESDPIKFHHVAPSFHSGENITTKISKPTYSNIFGDWICQKAAKDKRLVGITPAMKEGSDLIRFSQLYPHRYFDVAIAEQHAVTFAGGLACQGLKPVVAIYSTFLQRAYDQVIHDIALQNLDVLYAVDRAGLVGADGATHDGSFDLAFMRCIPNHVIMTPSDENEAYHMLEFGYEYNGPAMVRYPRGAGIGAEITGSLDLELGKAKIVKQGSKIAILNFGTLLPLAKQLAEKYHATVIDMRFVKPLDEIMLDKVSQTHEIILTLEENCIAGGAGSAVNEYFVAKDLSNKIIVRNFGLQDKFLNHGTKDLLLAQSKLCVENISQELDKLI
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CYB_MORBL
Sequence: MTNIRKTHPLLKIVNTSFVDLPAPSSLSSWWNFGSLLGICLGLQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIISALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLLMLTALSALVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAVIPLIHTSKQQSMIFRPLSQCLFWLLVADLLTLTWIGGQPVEHPYIIIGQTASILYFLIILILMPLVSAMENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ECTC_OCEIH
Sequence: MIVKSLEDIQGTEDHQKGETWESRRFVLNKDNVGFSLNDTIIKAGTESYFWYKNHIEAVYCIEGEGEVEKKDTGEVWQLKPGTMYLLNDNDKHYLRAKTQMRMVCVFNPALVGTETHDEDGVYPLLAE
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.
Protein: RK32_COFAR
Sequence: MAVPKKRTSTSKKRIRKNIWKKKGYWTALKAFSLGKSLSTGNSKSFFVQQTNK
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSB3_GIAIN
Sequence: MGNIWEYNGSALIGIKGXDCVALAADKRLGCSYQTLTIGNEERIFRLSQSCLLGLAGLQTDVLTTYRQIRMKSNLYHLQEDREIRPRATAKMISSFLYKHRFGPYFISPIIAGFEADGKPYLGAMDTIGCLDDCTNFQIAGTASDFLLGLCETHVKPDMSEDEILPLMEQIIRSATNRDAYSGWGAHVVVLRRDGTTSDIPISTRMD
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Proteasome subunit beta type-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YR679_MIMIV
Sequence: MSTLIDNHIEHLSKLSDKKICRILRIKPSKDIDKNDLITKLILDHYYGKPRLGNIIVIKSLQNGGVRNWEFNLEEIDSNNRQLDSTIPWNNDYSLREIQNTLNHRYNNINQDLVDLLSVDDMNNSLNTDFLKKFYTYFYIGNYNRDKLCQTMKTFAKSTKKVTSNGITKNKTVGKGAAGIAFLAETNSGSFEFVIKAMNNVKQYRNKSLDIGTILYKSELPLRSNVKNNHLEYLATDVMRTVELRYPGYSGYNAFISNEGLLYLNSANDNFTNQTIMHIVLNRILTQYDNDHFIYQFDAFFCENRSGLKRGTSTLTNKITLGKTNSTNVKQTDGYNIMEFANAGSLDAILDDWSKSINIDSNYETLLFMFNDIFVQILKTLKILQQPKFAFVHGDLKTKNIFVKTDGQINLPNGQVFPRYIYKIADYDKSSITWNGIRFHNSGNLGTNIIGKLYDNLNTLDLTSTVDSNYYYLTNICPFIESCTSIINGIELESIPIRYLPIPFYSSIDVYSFVTSMLCHKIFHNFVDYCLVRSIDNEITNILKHLFTETDLNIVMDHINNTFNSNKKLDLTKYGKIISIIKNNHIGLRKNINKIYDIYGIKLHMKETRTVVPNIILSADQNICLDKCKLNTCNIIQSTRYNRLSDQCYWKSTNSETQELHISDSDQIDREIDSDEQKQIIDNLFNDIKQQSKK
What are the official names of this protein?
Putative serine/threonine-protein kinase R679.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Virion.
Protein: NDHJ_MORIN
Sequence: MQGRLSVWLIKHGLVHRSLGFDYQGIETLQIKPEDWHSIAVILYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIEYGIDQPEEVCIKVFAPRRNPRIPSVFWIWKSADFQERESYDMLGISYNNHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAH
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, chloroplastic, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: VPS4A_RAT
Sequence: MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCMQYLDRAEKLKDYLRNKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSVMIDDLLTPCSPGDPGAIEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES
What is the function of this protein?
Involved in late steps of the endosomal multivesicular bodies (MVB) pathway.  Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission.  Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting.  MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.  It is required for proper accomplishment of various processes including the regulation of endosome size, primary cilium organization, mitotic spindle organization and chromosome segregation, and nuclear envelope sealing and spindle disassembly during anaphase (By similarity).  In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.  Involved in cytokinesis: retained at the midbody by ZFYVE19/ANCHR and CHMP4C until abscission checkpoint signaling is terminated at late cytokinesis.  It is then released following dephosphorylation of CHMP4C, leading to abscission.  VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).  Critical for normal erythroblast cytokinesis and correct erythropoiesis (By similarity).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 4A.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein. Midbody. Cytoplasm, cytoskeleton, spindle. Note=Membrane-associated in the prevacuolar endosomal compartment. Localizes to the midbody of dividing cells, interaction with ZFYVE19/ANCHR mediates retention at midbody. Localized in two distinct rings on either side of the Flemming body.
Protein: OGT_SULAC
Sequence: MIVYGVYNSPLGTITVAKNERGIIMLDFCDCAERNLVDNSTFTDLFHKFDNYFQGKPVEFNETVDLFVNNFRRRVFNEVRRIGWGKVKTYKEIAETLKTSPRAVGMALSKNPVLLIIPCHRIIAESGLGGFSRGIELKKKLLELEGVNIEALVRG
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_RICPU
Sequence: MSKINKLEHIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCRWQDKIINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYRCVEMLKDRLGAKPLVIQLPVGIEENFKGIIDLIKMKAVIWKDEALGAEYFEEDIPADMKDKAEEYRAKLLDMVVELDDHVMEKYLSGEEVTAEEIKRLIRKGTISAAFYPVLCGSAFKNKGVQPLLDAVVDFLPSPIDIGIVKGMEVSTGEEKDFPISVTEPFAALAFKIMNDPFVGSLTFIRIYSGKITSGTTVINTVKNKREKIGRMLLMHANNREDVKEASAGDIVALAGLKDTTTGDTLSDIDQQVILERMEFPEPVIELAVEPKSTADQEKMGLALSRLAAEDPSFRVSTDYETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRETITKVCEIDYTHKKQSGGAGQFARVKIIFEPLKEVKDLKDEDKNKIFVFESKIIGGAVPKEYIPGVEKGLNNIRETGVIAGYPMIDFKATLVDGAFHDVDSSVLAFEIAAKAAFREGMPKGNPKLLEPIMQVEVITPDEYMGDIIGDLNSRRGQIQSMDPRGNAQVVTANIPLAEMFGYVNTLRSLSQGRAQFSMIFSHYDQVPSQVADIIKAKK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_ECO45
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COFD_METB6
Sequence: MITFLSGGTGTPKLLRGMQKVTDRHEISVVVNTAEDIWISGNHISPDVDTVMYLFAGVLNTDTWWGIRNDTFVTHEEILHLGLGEYIAIGDRDRAVHIARGNMLREGMRLTNATRTLCERFGVRENVLPMSDTEVTTRVKTELGLIHYQEYWIRSRGQIRIEDVVRCSKVPPESSEEVIQAVEASDVVVIGPSNPITSITPILECKGIREAMEDKYVIAVSPFIGNVPVSGPAAALMQASGFEPTSAGTAACYKDLVDLFIHDIRDPVEMREAIRLDTLMTGEEKSIGLAEQILALAKRAKA
What is the function of this protein?
Catalyzes the transfer of the 2-phospholactate moiety from (2S)-lactyl-2-diphospho-5'-guanosine to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of oxidized coenzyme F420-0 and GMP.
What are the official names of this protein?
2-phospho-L-lactate transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: MNTH_XYLFT
Sequence: MSCCIANAIRWDVSLLIHRSMSSSMSSVQPTSPVSDSPSLGEMHASVAVSRRGHWGFRLLAFLGPGYMVSVGYMDPGNWATGLAGGSRFGYMLLSVILLSNVMAIVLQALAARLGIASDMDLAQACRARYSRGTNLALWAVCELAIIACDLAEVIGTAIALNLLLGVPIILGAVITAVDVVLVLLLMHRGFRALEAFVIALLLVIFGCFVVQIVLAAPPLQEVLGGFVPRWQVVADPQALYLAIGIVGATVMPHNLYLHSSIVQTRAYPRTPVGRRSALRWAVADSTLALMLALFINASILILAAAVFHAQHHFDVEEIEQAYQLLAPVLGVGVAATLFATALLASGINSTVTATLAGQIVMEGFLRLRLRPWLRRVLTRGLAIVPVIVVVALYGEQGTGRLLLLSQVILSMQLPFAVIPLLRCVADRKVMGALVAPRWLMVVAWLIAGVIVVLNVKLLGDYAVHLMVGVSD
What is the function of this protein?
H(+)-stimulated, divalent metal cation uptake system.
What are the official names of this protein?
Divalent metal cation transporter MntH.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ELOA1_HUMAN
Sequence: MHGGRSCGPRTRREPSSGEEAAPVTAMAAESALQVVEKLQARLAANPDPKKLLKYLKKLSTLPITVDILAETGVGKTVNSLRKHEHVGSFARDLVAQWKKLVPVERNAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGHSNAFQDRLGASQERHLGEPHGKGVVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPEGKVKTNLDRKSLGSLPKVEETDMEDEFEQPTMSFESYLSYDQPRKKKKKIVKTSATALGDKGLKKNDSKSTGKNLDSVQKLPKVNKTKSEKPAGADLAKLRKVPDVLPVLPDLPLPAIQANYRPLPSLELISSFQPKRKAFSSPQEEEEAGFTGRRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEEYNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRVLTKNIQFAHANKPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKIKIKPAPYPMGSSHASASSISFNPSPEEPAYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAFKNRFSRR
What is the function of this protein?
As part of a multisubunit complex composed of elongin BC complex (ELOB and ELOC), elongin A/ELOA, RBX1 and CUL5; polyubiquitinates monoubiquitinated POLR2A.
What are the official names of this protein?
Elongin-A, EloA, Elongin 110 kDa subunit, RNA polymerase II transcription factor SIII subunit A1, SIII p110, Transcription elongation factor B polypeptide 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: TNFA_NOTEU
Sequence: MSTENMIRDVELAEEELQRKARGPQGPGRCLCLILTFFLLLAGATLLFCLLHFGVIGPQNEEASTDAFLGMKPVTQRVRSCQTESNKPVAHVIADPLAEGKLQWLKRRANVLLSNGMDLVDNQLVVPSTGLYLVYSQLLFKGEDCANEPLLLTHTVSRVALSYQSKVNLLSAIKSPCQKTVKGAREASPWYEPIYLGGVFQLEKGDKLSADTNYPNYLDFAESGQVYFGVIAL
What is the function of this protein?
The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
What are the official names of this protein?
Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted. SUBCELLULAR LOCATION: [C-domain 1]: Secreted. SUBCELLULAR LOCATION: [C-domain 2]: Secreted.
Protein: GATB_JANMA
Sequence: MQWEVVIGLETHTQLTTQTKIFSGSPTQFGAEPNTQTSPVDLALPGALPVMNRGAVERAIQFGLAIGATIAPHSVFARKNYFYPDLPKGYQISQMDLPIVQGGRVSFALEVDGKTEIRSVQLTRAHLEEDAGKSLHEDYQGMTGIDLNRAGTPLLEIVTEPDMRSAAEAVAYAKALHTLVTWLGICDGNMQEGSFRCDANVSVRPVGQKEYGTRCEIKNLNSFRFLEDAINYEVRRQIELIEDGGRVVQATRLYDPDKKETREMRSKEDAHDYRYFPDPDLPPLVVSAEWIARVQAAMPELPGAMRERFVRDYALSEYDAAVLTQSKGMANYFEAVVAAAGKEQAKPAANWLMGDVASTLNREDIEIAAAPVAAAQLALLLQRIADGTISNKIAKEVFGAMWEAKSDSAKLADELIESKGLKQISDSGALEKIVDDVLAANAKSVEEFRAGKEQAINALMGQAMKASKGKANPAQLTELLKKKLTA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: NECD_MOUSE
Sequence: MSEQSKDLSDPNFAAEVPDCEMQDSDAVPVGIPPPASLAANLAGPPCAPEGPMAAQQASPPPEERIEDVDPKILQQAAEEGRAHQPQSPARPIPAPPAPAQLVQKAHELMWYVLVKDQKRMVLWFPDMVKEVMGSYKKWCRSILRRTSVILARVFGLHLRLTNLHTMEFALVKALSPEELDRVALNNRMPMTGLLLMILSLIYVKGRGAREGAVWNVLRILGLRPWKKHSTFGDVRKIITEEFVQQNYLKYQRVPHIEPPEYEFFWGSRANREITKMQIMEFLARVFKKDPQAWPSRYREALEQARALREANLAAQAPRSSVSED
What is the function of this protein?
Growth suppressor that facilitates the entry of the cell into cell cycle arrest.  Functionally similar to the retinoblastoma protein it binds to and represses the activity of cell-cycle-promoting proteins such as SV40 large T antigen, adenovirus E1A, and the transcription factor E2F.  Necdin also interacts with p53 and works in an additive manner to inhibit cell growth.  Also functions as a transcription factor and directly binds to specific guanosine-rich DNA sequences.
What are the official names of this protein?
Necdin.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix. Note=Mainly cytoplasmic. Translocates to the nucleus where it is found associated with the nuclear matrix.
Protein: COXM2_BOVIN
Sequence: MHPDLSPHLHTEECNVLINLLKECHKNHSILKFFGHCNDLDREMRKCLKNEYMEKRNKSRELGNAMRKRLFNPPEESEN
What is the function of this protein?
May be involved in cytochrome c oxidase biogenesis.
What are the official names of this protein?
COX assembly mitochondrial protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the CMC family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CMOA_YERE8
Sequence: MPKRETQSLHDTQQQPGPTAPQRDSLFAAPIAKLGDWTFDEKVAEVFPDMISRSVPGYSNIISMIGMLAERFVQPNSQIYDLGCSLGAATLSMRRNIKVEGCKIIAVDNSPAMIERCRRHIDAFRAETPVDVVESDILDIQLENASMVVLNFTLQFLEPADRQRLLNQVYQGLRPGGALVLSEKFNFEDNDVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKKRLHQAGFEHAEVWFQCFNFGSLIALKAGEAQ
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: METAA_BACFN
Sequence: MPLNLPDKLPAIELLKEENIFVIDNSRATQQDIRPLRIVILNLMPLKITTETDLVRLLSNTPLQVEISFMKIKSHTSKNTPIEHMKTFYTDFDKMREDRYDGMIITGAPVEQMEFEEVNYWDEITEIFDWARTHVTSTLYICWAAQAGLYHHYGIPKYALDKKMFGIFKHRTLLPLHPIFRGFDDEFYVPHSRHTEVRKEDILKVPELTLLSESDDSGVYMVVARGGREFFVTGHSEYSPLTLDTEYRRDVSKGLPIEIPRNYYVNDDPDKGPLVRWRGHANLLFSNWLNYFVYQETPYNIEDIR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCSA_PANGI
Sequence: MIFSTLEHILTHISFSIVSIVITIHLITLLVDEIIKLYDSSEKGMIAIFLCITGLLVTRWIYSRHFPLSDLYESLIFLSWSLSVIHIVPYFKKKKKNLSTITASSVIFTQGFATSGLLTEIHQSAILVPALQSEWLIMHVSMMILSYAALLCGSLLSVALLVITFRKNRNIFCKRNPLLNELFSFGEIQYMNERNNVLRTTFFSAKNYYRSQLIQQLDYWSYRVISLGFIFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWIVFAIYLHTRTNIKLRGANSAIVASIGFLIIWICYFGVNLLGIGLHSYGSFTLTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MP8_TNVA
Sequence: MDYQTDVTEDNVQIRGRARSVEGKKHNGSGLTGVKRHAVSETSQKSQQGTGNGTMTNIAEEQTITVTYNFNF
What is the function of this protein?
Cell-to-cell movement.
What are the official names of this protein?
Probable movement protein p8.
What is the protein family that this protein belongs to?
Belongs to the carmovirus/necrovirus/panicovirus movement protein p8 family.
Protein: COAX_ROSCS
Sequence: MLLTIDIGNTNIKIGAYQGERLTAHWRVTTERHRLADEYLVLLHNLFDLGGIDPRHIDGCAISCVVPPLTGEFRALCHKYFRVDPLMVNASTPTGLQYKVDAPAELGADRIANSLAAFRRYGGPVIVLAFGTATTFDVITATGEYIGGAIAPGIGISADALFRLAAKLYQVELVRPPKVIGTNTIHHMQSGVILGYAGLVEGLVRRMQAELGTSCPVVATGGLAELIAAETEAITTVEPYLTLDGLRLIYEMNRQ
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y173_HAEIN
Sequence: MQTLFFTLIAFVAIILLMSIGFIIKKQSLKGSCGGLSTLGIAKACDCDKPCDTHHSKLDAGDEQAKAEYEQKFAKKDDDSQFYQVK
What are the official names of this protein?
Uncharacterized protein HI_0173.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: LSPA_ESCF3
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILVVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.