PharMolix/UniProtQA huggingface dataset:
Protein: GLND_AZOVD
Sequence: MPQVDPDLFDPGQFQAELALKSSPIPAYKKALRCAREVLDARFQEGRDIRRLIEDRAWFVDQILALAWNRFDWSEDADIALIAVGGYGRGELHPYSDIDLLILMDGADHEVFREPIEGFLTLLWDIGLEVGQSVRSLAECAEEAQADLTVITNLMESRTIAGPEHLRQRMQEVTSAQRMWPSRAFFLAKRDEQKTRHARYNDTEYNLEPNVKGSPGGLRDIQTLLWIARRQFGTINLHAMVGQGFLLESEYTLLASSQEFLWKVRYALHMLAGRAEDRLLFDLQRQIAGLLGYEDSDAKLAVERFMQKYYRVVLGIAELTELVFQHFEEVILPGDAAGRVEPLNERFQVRDGYLEVTHAGVFQETPSALLEIFVLLARRPEIRGVRADTIRLLRDHRYLIDDAFRRDPHNTGLFIELFKSRQGIHRNLRRMNRYGILGRYLPEFGHIVGQMQHDLFHIYTVDAHTLNLIKNLRKLFWPELAEKYPLASKLIEKLPKPELIYLAGLYHDIGKGRGGDHSELGAADALAFCQRHDLPAMDTQLIVWLVRNHLLMSTTAQRKDLSDPQVIFDFAQKVRDQTYLDYLYVLTVADINATNPTLWNSWRASLLRQLYTETKHALRRGLEQPVGREEQIRQTQKAALDILVRSGTDPDDAEHLWTQLGDDYFLRHTSSDIAWHTEAILQHPSSGGPLVLIKETTQREFEGATQIFIYAPDQHDFFAVTVAAMDQLNLSIHDARVITSTSQFTLDTYIVLDADGGSIGNNPARIQEIRQGLVEALRNPADYPTIIQRRVPRQLKHFAFAPQVTIQNDALRPVTILEIIAPDRPGLLARIGKIFLDFDLSLQNAKIATLGERVEDVFFVTDAHNQPLSDPELCARLQLAIAEQLADGDSYIQPSRISI
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: DCTA_XYLFA
Sequence: MHLSSRANAPAPHKPYNPFYLQLYFWVIIAIILGALLGHCYPVVGQQLKPLGDAFIKLVKMIISPVIFLTIVTGIASVAHVGTVARVFGKAMVYFLFFSTLALLLGLVVAHVVHPGVGMNINPADLHQGEIASYVEKSHDLTLVGFLMDIIPKTLLSPFVGDNILQVLFVAVLFGIALALAGERGKPVLNLLDALTLPVFKLVQMLMKMAPIGAFGAIAFTIGKYGVDSLVNLGWLVGSFYLTSLLFVLVILGAVSWFSGFSILKLIRYLKSELLLVLGTSSSEAALPSLMEKMVQAGCKKSVVGLVVPTGYSFNLDGTNIYMTLAALFIAQATNTELTPAHQLALFLVAMLSSKGAAGVSGAGFITLAATLTVVPEVPIAGMALILGVDRFMSECRSLTNFIGNAVATLVVSRWENALNHEQLKIALDGSEPAYQSLHAKDAEPSVSR
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the inner membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCY_HYDS0
Sequence: MNYKIIAIDGPASSGKSSVSRELSKILGYIYFNTGLVYRAIGFLKSKNIDFFDAVEKNRLVFELLIGQTKVIFDHDDITKELTKEYVGALASEVAKEPSLREKIIVFQRSLVKDNAVVEGRDVGTHIFKDATIKFFIDADPKERALRRYLEEGGSYEDILNKILKRDETDKNRKDYPFRKAEDAIQIDTTCMTKEEVINLCMEYIKKVL
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCC4_HUMAN
Sequence: MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKAVEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEY
What is the function of this protein?
Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators, such as CREB1, MEF2D, JUN and RORA, which play pivotal roles in immune response, inflammation, and memory consolidation.  In the thymus, regulates the CD4(+)/CD8(+) double positive thymocytes selection threshold during T-cell ontogeny.  In CD4 memory T-cells, is required to link T-cell antigen receptor (TCR) signaling to the production of IL2, IFNG and IL4 (through the regulation of CREB and MEF2).  Regulates the differentiation and survival phases of osteoclasts and dendritic cells (DCs).  Mediates DCs survival by linking TLR4 and the regulation of temporal expression of BCL2.  Phosphorylates the transcription activator CREB1 on 'Ser-133' in hippocampal neuron nuclei and contribute to memory consolidation and long term potentiation (LTP) in the hippocampus.  Can activate the MAP kinases MAPK1/ERK2, MAPK8/JNK1 and MAPK14/p38 and stimulate transcription through the phosphorylation of ELK1 and ATF2.  Can also phosphorylate in vitro CREBBP, PRM2, MEF2A and STMN1/OP18.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type IV, CaMK IV, CaM kinase-GR.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized in hippocampal neuron nuclei. In spermatids, associated with chromatin and nuclear matrix (By similarity).
Protein: DRC1_MOUSE
Sequence: MNPSGTIGVLEQNGEEHLATPILGPSVHSDNPQERIQARRLRIAARQEARRREALGEYLDGKKESEEEQSKSYKQKEESRLKLTKLLLCGTELVTNIQVAADVREIHRRVEEEETKRQRLEKLENEVKTSQDKFDEITAKWEEGRRKRIPQELWEMLNSQQVHCAELIEDKNKLANELQQELKIKDDQYVKDLKKQSEDITLILERMEEQVKNVMKNFRQELIHIEKAFESERQELLSSNKKKWERALQAHNAKELEYLTNRMKKVEDYEKQLNKQRVWDCEEYNTIKIKLEQDVQILEQQLQQMKATYQLNQEKLEYNFQVLKKRDEESTVIKSQQKRKLNRLHDVVNNLRTKYTKQIRQFQDDNQSLTSDYKRLVTQFKDLQKALRHFIIIDEEKFREIWLMNEAEAKELAQRAFDVDRIIHSQHLGLPWNMPDLWFLNNVGPISLQQQKSVTQILEELLLQTEDEATEAAMSEDEDYMDLPNQISAKTTTKVLMLLCDESGFLIESKLLSLLHPLEKSECYLLRLDAIFSALAIEDEDDLYKLVNFFLRYRAHRLSSAQASSSIHSNVERTSLMSALERLSLMSQTDKGSMVSKSDQEPTEQEDEQEGDNASLSSRELEEQEDLSSPRFIHPNDVLKILEAFVTGLKKPKDAQPVLKLKKETRDNSKDTEYWESLAAVIPFFKQNLWDALYKALEKYYLVLTERAKLLMENESLEQQNAEMQSLLQQYLQAKVNTELQIPPTQGFRMPSK
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes.  Coassembles with CCDC65/DRC2 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
What are the official names of this protein?
Dynein regulatory complex protein 1, Coiled-coil domain-containing protein 164.
What is the protein family that this protein belongs to?
Belongs to the DRC1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: SHDAG_HDVV3
Sequence: MSQPDARPGSKAREEALEQWVEERKKKRIAEKELRRINKKIKKLEDENPWLGNIVGMLRKKKDEEGGPPAKRPRREDMEIDSTPGRKSKARGFTDQERRDHRRRKALENKKKQLAGGGKNLSREEEEELRRLARDDDERERRVAGPRPGGVNPMDGPPRGAPGGGFVPSLQGVPESPFSRTGEGIDIRGTQQFP
What is the function of this protein?
Promotes both transcription and replication of genomic RNA.  Following virus entry into host cell, provides nuclear import of HDV RNPs thanks to its nuclear localization signal.  May interact with host RNA polymerase II thereby changing its template requirement from DNA to RNA.  RNA pol II complex would then acts as an RNA-directed RNA polymerase, and transcribe and replicate HDV genome (By similarity).
What are the official names of this protein?
Small delta antigen, S-HDAg, p24.
What is the protein family that this protein belongs to?
Belongs to the hepatitis delta antigen family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: TATB_CERS1
Sequence: MFDIGWSELLVIGVVALVVVGPKDLPEMFRTLGRVTAKARNMAREFQRAMEAAADETGVKDVVKDVKNVTSPRSMGLDAMKQAADRFEKWDPMKPQQGAPKPAAPASSIPAAKAQQGAGAAAVTAPPASEPAAPVPQAPAAAAPEAASPAPAEPKSNA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SCX2_CENSC
Sequence: MNSLLIITACLFLIGTVWAKEGYLVNKSTGCKYGCLKLGENEGCDKECKAKNQGGSYGYCYAFACWCEGLPESTPTYPLPNKSCSRK
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  Induces immediate paralysis in crickets after injection, with a total paralysis occurring within 15-30 minutes and lasting for 1-2 hours.  Is also lethal to vertebrate (chicks) when injected in very high dosages (more that 100 mg/kg).
What are the official names of this protein?
Toxin CsEv2, CsE-v2, Neurotoxin 2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPP_CHICK
Sequence: MSHPSWLPPKSTNEPVGHVTARMETTHAFGTPSISVSTQQTPKKFAPVVAPKPKYNPYKQPGGDGDFLPPPPPPVDDLGNITSQGAFPPPPPLDDVAFNVQVNPGGKTLEERRSSLDAEIDSLTSILADLESSSPYKPRIQQGSGTSSSAATTPSVSTPVTGHKRMIIPNQPPLTATKKSTAKGPGQPAPIPVTPIGTLKPQPVPASYTTASTPSRPTFNVQVRTAQPSPHYQPPGPQPTHYGSLGPGQPYAAPPARPPGAQQYGSPQPRGPDYGYAPPPARPSEPSYGYAPQQGRYQDPYYGGYGGRNGSEAPYMPQSTWKVEPAYPSSNTVGQAPPGMYQHPGPKKTYITDPVLAPQPLQQKSGYPSSGPTSSTPAFRPEDELEHLTKKMLYDMENPPSDDYFGRCARCGENVVGEGTGCTAMDQVFHVECFTCMMCNNKLRGQPFYAVEKKAYCEPCYINTLEQCSVCAKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDAGGNIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGGLLSEGDNQGCYPLDGHILCKTCNSARIQALTAKASTDL
What is the function of this protein?
May play a structural role at sites of cell adhesion in maintaining cell shape and motility.  May be involved in signal transduction from cell adhesion sites to the nucleus (By similarity).
What are the official names of this protein?
Lipoma-preferred partner homolog.
What is the protein family that this protein belongs to?
Belongs to the zyxin/ajuba family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell junction. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites.
Protein: TAGU_BACC0
Sequence: MKKKILFWVLGILGVLIIGGGIYAYNVYSSVSNTLKEVHQPLKRDQNNSNVGEKVSKSEPVSILLLGADERGDDKGRSDSLMVITLNPKNNSMKTVSIPRDTYTEIVGKGKSDKINHAYAFGGVDMSVATVEKFLDVPINYYIEVNMEGFKDIVDAVGGVDVTNDLEFTQDGHHFAKGNIHLTGDQALAFTRMRKQDPRGDFGRQMRQRQVMQGVIKKGASFSSLTGYGDVLAAIQKNVKTNLTQDQMFDMQKNYKDCLKNSEDIQIPGDGHKAADGIWYYYVPDAAKQDLTNKLRSHLEVTK
What is the function of this protein?
May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG).
What are the official names of this protein?
Polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase TagU.
What is the protein family that this protein belongs to?
Belongs to the LytR/CpsA/Psr (LCP) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: RBR1_WHEAT
Sequence: MQLFKETKIILLSSMSSLGSGSPEEIERSWCACVLYCVSKLGNAGKAKEDRGITLRQILRAFDLKIVDFFKEMPQFCIKVGFILTGLYGSDWEKRLELQELQANLVHLCSLGRHYRRAYQELFLLNDGKPANNSSELNVQQASEYYDFGWLLFLVLRNQASSAVKNLLTSTTELVSVLAVLIIHIPVRLRNFSIEDSSCFAKKSDKGVNLIASLCERYLTSEDELSKALQKTNILIKDILKKKPCSDVSECQQGSLSFIDPEGLTFFKNFLEEDSLKSSLQVLEKEYVNGLDTKGELDARMFANEEDSLLGSGSLSGGALKLPGTKRKYDDVMASPTKSTASRAPMSPPRFCPSPNGNSFCNSKMAPFTPVSTAMTTAKWLRSTISPLPSKPSGELLRFFSACDKDVTDDITCRAAIILGAIFTGSSFGERMCTSLRNTSGMDAIWTEQRKMEALKLYYRVLESMCRAESQILSGSNLTSLLSNERFHRCMIACSAELVLATHKTVTMMFPAVLEKTGITAFDLSKVIESFVRHEDSLPRELKRHLNSLEERLLESMAWEKGSSMYNSLIVARPTLSAEINRLGLLAEPMPSLDAIAVHHDISLGGLPPLPFHKQPDKDEVRSPKRACTERRNVLVDNSFRSPVKDAIKSKFLPPLQSAFASPTRPNPAAGGETCAETGIGVFLSKITKLAAIRIKCLCERLQLSQQILERVYSLVQQIISQQTALFFNRHIDQIILCCIYGVAKISQLALTFKEIIFSYRKQSQCKPQVFRSVYVNWPSRSRSGKIGEDHVDIITFYNEVFIPTVKPLLVDLGPGTSPNRNNEPKSGGDAASFPESPRLSRFPNLPDMSPKKVSATHNVYVSPLRSSKMDTLLSPSSKSYYACVGESTHAFQSPSKDLNAINTRLNSGKKVNGRLNFDVVSDLVVARSLSDQNGSSAAAMAVFGTKTPVKGEQQDP
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein 1, TaRBR1.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SRP54_HALLT
Sequence: MVLDDLGTSLRSSLDKLQGKSRLSESDVEEIVKEIQRSLLSADVDVSLVMELSDSIKTRALEEEPPGGTTAKDHVLKIVYEEMVELVGDSTELPLENQTILLAGLQGSGKTTSAAKMAWWFSKKGLRPAVIQTDTFRPGAYDQAKQMCERAEVDFYGDPDNDDPVAIAREGLEATADADVHIVDTAGRHALEDDLIAEIEEIERAVDPDRSLLVLDAAIGQGAKEQARQFEKSIGIEGVMITKLDGTAKGGGALTAVNETDSSIAFLGTGETVQDIERFEPSGFISRLLGMGDLKQLSERVERAMAEAQEEDEDWDPEDMLQGEFTLKDMKRQMDAMNRMGPLDQVMDMIPGMGGGMMDQLPDDAMDVTQDRMRRFERIMDSMTDEELEQPRVVGQSRTERIARGSGTDEETVRQLLEQHSMMEQTISQFQGMGEGDMQRMMKKMGGGEGGGLGDMMGGGKGPF
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: RNPH_MYCLB
Sequence: MSTRADGRLDDELRAVVITRGFTEHPAGSVLIEFGHTKVMCTASPTEGVPRWRKGSGKGWLTAEYAMLPSATHTRSERESVKGRLSGRTQEISRLIGRSLRACIDLAALGENTIAVDCDVLQADGGTRTAAVTGAYVALADAVTYLSAAGRLLDPRPLSCAIAAVSVGVVDGRIRVDLSYEEDSRAEVDMNVIATDTGTLVEIQGTGEGATFPRSTLDKLLDMALGACDKLFVAQRDALALPYQGMSPEGPPPPKAFGS
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: CH10_BACLD
Sequence: MLKPLGDRVVIELVESEEKTASGIVLPDSAKEKPQEGKVVAAGSGRVLESGERVALEVKTGDRIIFSKYAGTEVKYEGTDYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2355_VIBCH
Sequence: MLIVVSPAKTLDYESPVSTSNFTQPELTAHSAELIQVCRTLSSQDVSELMSVSDKIAGLNVARFAQWSETFTLDNARQAIFAFKGDVYTGLEAETLSPQDLDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGTKLANARGANLYQFWGDIITEKLNQAIEAQGDNVLVNLASNEYFKAVNPKRLNAQIVTPIFKDAKNGQYKIISFFAKKARGMMARYIIENRIKSVKDLEGFNTAGYYFVASESTPTELVFKREEQ
What are the official names of this protein?
UPF0246 protein VC_2355.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RL30_SALA4
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAVRGMVNAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ZDHCS_CAEEL
Sequence: MSWYSKIYVAVREYRAKHKITGWILTRCLNVLLFIQLILLWWSLYMYVTVTIGYYVQSTIQATIYLIVGSFLFVMSMWSLAKTLFTRVGRVPERYRPSKELEDRLKAVTPMEKNRYVVEKSTPEQLAQQNTILEEMCTYCKVVVAECDQVGRLKYCYECGHIKPDRARHCSSCGKCCIKYDHHCPWINMCVTHVNYKYFLLYIIYTSFLVYWYLLTSLEGAVRYFINQQWTDELGKFLFYLFSFIVGGVFGYYPLGELIIFHYQLISLNETTVEQTKPALLRFDNAADYNMGKYNNFQSVFGWGLWLCPIDSSTQDGLHFDIRYVNTQQRNRFVRIEEEPSSTQSSQSSIQ
What is the function of this protein?
Involved in spermatogenesis, specifically in the morphogenesis of fibrous body-membranous organelles (FB-MO), which are Golgi-derived organelles used for transporting sperm-specific components, in spermatocytes and in their localization into budding spermatids (PubMed:16143610, PubMed:2744235).  Required for the proper formation of spermatids and spermatozoa (PubMed:2744235).
What are the official names of this protein?
Palmitoyltransferase spe-10, Defective spermatogenesis protein 10.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Mainly found in fibrous body-membranous organelles.
Protein: PROB_PROM9
Sequence: MKTWVIKIGTSILRGTEETSTEEVIETLCRSFTSFLLKGNKLILVTSGAVGLGCQKLNIKTRPNDLSTLQATAAVGQVNLMSLYDKIFNKLGHNIAQILITKADFNSRESFNNASKTLKKLIDLNVIPIVNENDTVANEELKYGDNDTLSALVALAINANKLILLTDIENLYSKDPRKNKDAHPIKEVHNSELKEIKNKNNQNSNNEWGTGGISTKLISAEIATKGGVEVQLVDGTNKKNLIEIFNDNKIGTLFYPLEKPIGNKKSWLSHAIHTVGKITLDDGAFFAINKKGASLLAVGVKNVEGNFTVNQAVKIVNTDNKEVAKGLVSISSDNLRSILNNKDNNNSSIIVVHRDVLALS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMB_ECOLI
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: AMASY_HALMA
Sequence: MSVTRHYDREFVRTFFTSPTAVDGEEDSAKMLRSAGQLRGLQAPDVWVPDNEDATAPNMRAEGVENIIDVVANQGAEFPGEIHPRVVWHRESPATRYKGFQQMLEITDPENGAVEHIDGFVIPEVGDIDDWKKADEFFTIIEHEHGLEEGSLSMSVIVESGEAELAMGDLREEMGKPSNNLERMFLLVDGEVDYTKDMRAMTPTGELPPWPELRHNTSRGASAAGLIAVDGPYDDIRDVEGYRERMKDNRAKGMTGIWSLTPGQVVEANTAPLPPKTGSWLLEAGGQEVELEAQDGKQVYDGDDLSLEEVSDGGYVLQAGGDRLELDEDELTEELLDRTAYIPSMTDIVDSMEEFEAAKEAGKGAIAMTQAATLVINGVEVDISKDRMWDEATYQAAQTPITLFQDVYEHRPDQHEELAEMYGADIVERATAVGN
What is the function of this protein?
Involved in the methylaspartate cycle.  Catalyzes the biosynthesis of malate in two steps.  In the first reaction acetyl-CoA is condensed reversibly with glyoxylate to form (S)-malyl-CoA.  In the second reaction (S)-malyl-CoA is hydrolyzed to malate and CoA.  It can also catalyzes the condensation of propionyl-CoA with glyoxylate and of acetyl-CoA with pyruvate, however the CoA-ester hydrolysis reaction is highly specific for (S)-malyl-CoA.
What are the official names of this protein?
Apparent malate synthase, (3S)-malyl-CoA thioesterase, (S)-malyl-CoA lyase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: MLTF_PSEPG
Sequence: MFAHTALRQRCAKWLFATGLFLLLGACVEKPSTLERVKEDGVLRVITRNSPATYFQDRNGETGFEYELVQHFAEDLGVKLQIETADNLDELYDALGKPSGPVLAAAGLVSSERRKAQVKYSHPYLEVTPQVIYRNGRPRPTNAKGLVGKKIMVLKGSSHADLLAELKKQNPGLEYEESDAVEVVDLLRMVDEGQIDLTLVDSNELAMNQVYFPNVRVAFDVGDTRDQRWAVAAGEDNSLLNEINEFLDKAQKNGTLQRLKDRYYGHVDVLGYVGAYTFAQHLQQRLPKYEKHFKSYAKVEQVDWRLLAAIGYQESMWQPEVTSKTGVRGLMMLTQRTAQAMGVSNRLDPKQSIQGGAKYFMKIKEELDDSIQEPDRTWFALAAYNVGTGHLEDARTLAKREKLNPNKWLDVKKMLPRLSQKQWYRQTKYGYARGGEPVHFVANIRRYYDILTWVTQPQLEGQVAEGNLHVPGVNKDKPADQSPPM
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: Y1093_SHELP
Sequence: MLILVSPAKTLDYETPASTQTFTMPALLEHSEALIKVCRELTPADIASLMKVSDKIAGLNAARFAEWHRDFNLDNAKQALFAFRGDVYTGLDADTLSEGSLARAQQHLRILSGLYGLLRPLDLMQAYRLEMGTKLANDRGANLYQFWGDIVTQEVNKALAEQGDDILVNLASNEYFKSVKPKQIQGQVITPIFKDKKNGQYKVISFFAKKARGMMVRYMLDNKVSRYEELLKFDTAGYYYSEADSSVNEPVFLREEQA
What are the official names of this protein?
UPF0246 protein Shew_1093.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: QUEF_COXBU
Sequence: MSTLRVLHEKSELGKTTVYPKEYAPHLLLPIPRDLNRKTLNVNVSEPPPFYGYDLWNAYELSWLNEKGKPFAARGEFIIPATSSHLIESKSFKLYLNSFNNERFADAAAVSQTMKRDLSKRVNESVTVNFILHETEIPVAYSPKGSLLDVLDIAIDTYSPDPNLLSTSQETVTETLYSHLLKSNCPVTGQPDWGSIEIHYTGPKIDHVQLLKYIISYRNHEEFHEACVERFFMDILRHCRPQELTVQARYTRRGGLDINPYRSTNPTFSVQNHRSFRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_HELAH
Sequence: MNAKALYKKKALRDRRKLRIKSKLLGDALRPRVSVFRSNRYFYAQAIDDVKQSTITHIDGRKMGFKNTQEDAKKLGVLFAEELKKAGIERVVYDRNGYLYHGVVAAFAESLRENGIAL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.