PharMolix/UniProtQA huggingface dataset:
Protein: RNH3_STRPM
Sequence: MNTLVLKIDAILSKHLKKQLAPYTISSQNIYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHPFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNTISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNLFLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THI4_PYRIL
Sequence: MELKIARAIIKHGLEDLYEYSDVDVAIVGAGPAGLTAARYLAERGHKVVVYERRFSFGGGIGPGGNMIPKIVVQEEAVPVLRDFKIRYKPVGDGLYTVDPAELIAKLAAGAIDAGAKIILGVHVDDVIFRGDPPRVVGLLWVWTPIQMSGSHVDPLYTQAKAVLDATGHDAEVISIAARKVPELGIEVRGEKSAWAEVSEKLVVEHTGRVAPGLYVAGMAVCTVHGLPRMGPIFGGMLLSGRRAAEIIHKDLVEEVYAVRA
What is the function of this protein?
Involved in the biosynthesis of the thiazole moiety of thiamine.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
What are the official names of this protein?
Thiamine thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
Protein: Y2212_CHLTE
Sequence: MPAADTCVRNARLADASAISRITEGYAGEGIMLKRSVENIIEHIRDFFVADYKGQVIGCCAIAFYTVKLAEIRSLAVLEEFRNKGIGRLLVEKAEAVLSEEGVNEVFVLTLNSGFFKRMGYKEIEKEYFPQKIWRDCTNCPKRMACDEIAMVKTL
What are the official names of this protein?
Uncharacterized N-acetyltransferase CT2212.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family.
Protein: ATPF_PARPJ
Sequence: MNLNATLFAQMVVFLILAWFTMKFVWPPLINALDERSKKIADGLSAAEKGKAELEAAHKRVDQELAQARNDGQQRIADAEKRAVAVADEIKAQAQAEAARIIAQAKADAEQQVVKARETLRGEVAALAVKGAEQILKREVDQAAHADLLNQLKAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RUVA_BURM7
Sequence: MIGRIAGTLLEKNPPHILVDCNGVGYEVDVPMSTFYNLPHTGEKVVLLTQLIVREDAHLLYGFLTPPERSTFRELLKITGVGARMALAVLSGMSVAELSQAVTLQDAARLTRVPGIGKKTAERLLLELKGKLGADLGPLAGAASPSDHATDILNALVALGYSEKEALAAIKNVPAGTGVSEGIKLSLKALSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: YEBQ_ECOLI
Sequence: MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRITQPRSRA
What are the official names of this protein?
Uncharacterized transporter YebQ.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SST_XANOR
Sequence: MTEFIPLGTLYHALPSPFQMKRGGVLHQAHVAYETWGALAADRSNAVLIVTGLSPNAHAAANQANPEPGWWEAMVGPGKPIDTARWFVVCVNSLGSCKGSTGPASVNPATGALYRLTFPDLSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLLRHPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDTRYPESGMRMARKLGVITYRSALEWDGRFGRVRLDSEQSEDDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYVDDKPAADMGIDSPGADALPAAKSETGVSTASTVLAGLARIRIARALAIGANTDILFPVQQQEQIADGLRAGDADARFIGLDSPQGHDAFLVDFARFGPAVRDFLQGC
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.
What are the official names of this protein?
Serine O-succinyltransferase, SST.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_CORDI
Sequence: MAELTISSDEIRSAIANYTSSYSAEASREEVGVVISAADGIAQVSGLPSVMANELLEFPSGVIGVAQNLDTDRIGVVVLGNYEILKEGDEVKRTGEVLSIPVGEKFLGRVINPLGQPIDGLGAIEAEEQRVLELQAPSVLQRQPVEEPMQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCIDTILNQKANWESGDKSKQVRCIYVAVGQKGSTIAAVRQTLEEHGALEYTTIVAAPASDSAGFKWLAPFAGAALGQHWMYQGNHVLVIYDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDDMGAGSMTALPIIETKANDVSAFIPTNVISITDGQVFLESDLFNQGVRPAINVGVSVSRVGGAAQTKGMKKVSGSLRLDLAAYRDLEAFATFASDLDAASKAQLDRGARLVELLKQAENAPQSVEHQIVSIWLAGNGHFDTVPVEDIRRFEFDLIDHLHAAVPQVFEQIAGGAQLSEESQAALVAATEDFKRTFQTTDGTPVINEPEVAALSADQVKKNTISVKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TCPZ_CLAP2
Sequence: MNPMLTNNSQPSNYTAGNAKGKIKKLRSACDACHASKVRCSGEPICARCQRDNVACHYSYRAHQGKPKGSLNRKTIERMKAAGFIEQRQRPAASQPPGHGTSRDSSVCASGTTTDNLLNFIEIQPPGESNESPVAIHATPSPCFAMTGGLLPDFDAANLDAFLEAYQTPEDSCLRAVEEFPGASPADMDCIFIGTPSSMSRDYTEVATCRCVREITQQINNVHAASADRSTTGLDDVLHYTREISACISGLLQCYSCGGQVQVFVLASVVLSLLMELMHPLLDSSTDTSRPRAQIRVGNYDMSGQLGDVLEKVIVRSIITKLRQVVDKFEMKADFLRSETAQAEFLKSEARRLKRGFGRIEEGTATLP
What is the function of this protein?
Transcription factor that specifically regulates the thioclapurine biosynthesis gene cluster (PubMed:27390873).
What are the official names of this protein?
C6 finger domain transcription factor tcpZ, Thioclapurine biosynthesis protein Z.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL16_PSESM
Sequence: MLQPKRTKFRKQMTGHNRGLALRGSKVSFGEFALKSVARGRLTARQIESARRALTRHVKRGGKIWIRVFPDKPVTKKPLEVRMGKGKGNVEYWVAQIQPGKVLYEIEGVTEELAREAFALAAAKLPLATSFVKRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PKSG1_CANSA
Sequence: MNHLRAEGPASVLAIGTANPENILIQDEFPDYYFRVTKSEHMTQLKEKFRKICDKSMIRKRNIFLNEEHLKQNPKLVEHDVQTLDARQDMLVVEVPKLGKDACAKAIKEWGQPKSKITHLIFTSASTTDMPGADYHCAKLLGLSPSVKRVMMYQLGCYGGGTVLRIAKDIAENNKGARVLAVCCDIMACLFRGPSDSDLELLVGQAIFGDGAAAVIVGAEPDESVGERPIFELVSTGQTILPNSEGTIGGHIREAGLIFDLHKDVPMLISNNIEKCLIEAFTPIGISDWNSIFWITHPGGKAILDKVEEKLHLKSDKFVDSRHVLSEHGNMSSSTVLFVMDELRKRSLEEGKSTTGDGFEWGVLFGFGPGLTVERVVVRSVPIKY
What is the function of this protein?
Polyketide synthase responsible for the biosynthesis of secondary metabolites.
What are the official names of this protein?
Polyketide synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDPAS_HALLT
Sequence: MIGSLVATAFWAMLPAYVPNNAAVLAGGGRPIDGGRDWRGARLLGDGKTWRGTAVGTLTGVVLALALNRIAEPASAALGVDLPTFALPAAFALAFGAMCGDIGASFLKRRSGRERGAAFPGLDQLDFVVVALAAVFVVDTDWALAVFTPSVLVVVLVMTPILHVVTNVGAYALGLKNEPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPB_THEPX
Sequence: MSGRFGRFGGQYVPETVMNALIELEREFEKAKQDKDFMEEYRYYLREYSGRPTPLYYAENLTKKLGGAKIYLKREDLNHTGAHKINNVLGQILLAKRMNKKRVIAETGAGQHGVATATAAAMFGMECEIFMGEEDIKRQSLNVFRMKLLGAKVTPVKSGTGTLKDAVNEAIRDWVTNINDTFYVIGSVVGPHPYPTMVRDFQRVIGDEAKEQILQKEGRLPDYVIACVGGGSNAMGIFYPFIEDKEVKLIGVEAAGEGIETGKHAAAMAKGSVGVLHGMMTYLLQDEEGRIMPVYSISAGLDYPGVGPEHAFLKESNRAQYVYATDEEALAAFMDLSQTEGIIPALESAHALAYAMKLAPNLTKDNIIIVNLSGRGDKDVNTVAKVLGVEL
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: PANB_CLOBL
Sequence: MRNTVSTFQELKNKGEKITMLTAYDYSMAKLIDSSGINGILVGDSLGMVCLGYENTLSVTMEDMLHHTKAVVRGTSNALVVGDMPFMSYQTSIYDAVYNAGRFIKEAGAHAVKLEGGATVAEEIKAIVKAQIPVMGHIGLTPQSVNMFGGFKVQGKNEKVAKKLIEDAKILEEAGAFSIVLECIPEKLSKIISESISIPTIGIGAGKYCDGQILVYQDMLSMFSDFKPKFVKSFGNIGESIKDGVSQYIKEVKEAKFPEEKHAFKIDDDVINKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTJA_SALTI
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIVLFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH2B_SCHPO
Sequence: MQGKIFILPKDSTNQQFVELSHPLTGRPLRYLLTNDHLLQILQVGDSSKQRSWFVGDHVVSDGYLYVCTPIDLLALVLPIIQELTWSRRKEPNRYVSFEDFIEHFDNMGPHYPRVSEVLSPNLLNTLHRICKVNEPVGSLPKTFQLDESSVVKILLRKAKVAQENLPPSIVTELKKQLAPLDLRTPLPQDLLELSCKWHAASLVCEDLQPEWYNKLAYWQEELAPLHAYTKNLEESRKILVEKEALLNSKKRPQNSDITSSLLKKPNRKQATKKSKYFSGEGMTKISSFFTKK
What is the function of this protein?
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids.  Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication.  Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
What are the official names of this protein?
Ribonuclease H2 subunit B, RNase H2 subunit B, Rnh2B, RNase H(202), Ribonuclease HI subunit B.
What is the protein family that this protein belongs to?
Belongs to the RNase H2 subunit B family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NU4C_GOSBA
Sequence: MNYFPWLTIIVFLPISAGSLLFFLPHKGNKLIKWYTICICILELLLTTYAFCYHFRLDDPLIQLAEDYKWINFFDFYWRLGIDGLSIGPILLTGFITTLATLAAWPVTRDSRLFHFLMLAMYSGQIGSFSSRDLLLFFIMWEFELIPVYLLLSMWGGKKRLYSATKFILYTAGGSVFLLIGVLGLGLYGSNEPTLNFETLANQSYPVALEIIFYIGFLIAFAVKSPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSIFSPWLIIVGTMQIIYAASTSLGQRNLKKRIAYSSVSHMGFIIIGIGSITDTGLNGAILQIISHGFIGAALFFLAGTSYDRMRLVYLDEMGGMAVSIPKIFTMFSILSMASLALPGMSGFVAELIVFFGIITSQKYFLMPKILITFVMAIGMILTPIYSLSMSRQMFYGYKLFNAPSSYFFDSGPRELFVSISIFLPVIGIGIYPDFVLSLSGEKVETILYNYFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: NDB4T_MESMA
Sequence: MEIKYLLTVFLVLLIVSDHCQAFLSSLIPSAISGLISAFKGRRKRDLNGQIDHFKNFRKRDAELEELLSKLPIY
What is the function of this protein?
Antibacterial peptide.  This peptide gene is up-regulated at the transcriptional level after the venom gland is challenged by Gram-positive bacteria.
What are the official names of this protein?
Peptide BmKb2, Small cationic antibacterial peptide Kb1.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: HBA_EQUAS
Sequence: MVLSAADKTNVKAAWSKVGGNAGEFGAEALERMFLGFPTTKTYFPHFDLSHGSAQVKAHGKKVGDALTLAVGHLDDLPGALSNLSDLHAHKLRVDPVNFKLLSHCLLSTLAVHLPNDFTPAVHASLDKFLSTVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ZN708_HUMAN
Sequence: MGPLTFMDVAIEFSLEEWQCLDTAQQNLYRNVMLENYRNLVFLGIAVSNLDLITCLEQGKEPWNMKRHEMAAKPPAMCSHFAKDLRPEQYIKNSFQQVILRRYGKCGYQKGCKSVDEHKLHKGGHKGLNRCVTTTQSKIVQCDKYVKVFHKYSNAKRHKIRHTGKNPFKCKECGKSFCMLSQLTQHEIIHTGEKPYKCEECGKAFKKSSNLTNHKIIHTGEKPYKCEECGKAFNQSSTLTRHKIIHTGEKLYKCEECGKAFNRSSNLTKHKIVHTGEKPYKCEECGKAFKQSSNLTNHKKIHTGEKPYKCGECGKAFTLSSHLTTHKRIHTGEKPYKCEECGKAFSVFSTLTKHKIIHTEEKPYKCEECGKAFNRSSHLTNHKVIHTGEKPYKCEECGKAFTKSSTLTYHKVIHTGKKPYKCEECGKAFSIFSILTKHKVIHTEDKPYKCEECGKTFNYSSNFTNHKKIHTGEKPYKCEECGKSFILSSHLTTHKIIHTGEKPYKCKECGKAFNQSSTLMKHKIIHTGEKPYKCEECGKAFNQSPNLTKHKRIHTKEKPYKCK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 708, Zinc finger protein 15, Zinc finger protein 15-like 1, Zinc finger protein KOX8.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1457_BRUA4
Sequence: MTEITDRYFDDLIARLTGLRGRLAEPMAKAAELITAAALADNRVYVFGTGHSHMMAEELHYRAGGLAITVPILCGAIMLQDGAAASSHFERIKGAVLPILERYGIREGDVLIVVSNSGVNAAPIEAARYAREKGAAVIAVTSVTYSNAIAKGRTQLLSLADVVLDNDAPAGDAVLEMEGSSLKVGPVSTALGVTILNAIFADVAAKLVGKGDAPIYLSANMPGSGEVNRELVARYRDRNPHL
What are the official names of this protein?
UPF0309 protein Oant_1457.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: PNP_XANOM
Sequence: MAKITKTFQYGKHTVTLETGEIARQAGGAVIVKFDDTVLLVTAVAAKSAREGQDFFPLTVDYQEKFYAGGRIPGGFFKREGRATEKETLISRLIDRPIRPLFPEDYKNEVQIIATVMSMNPDIDGDIAALIGASAALSLAGTPFNGPIAAAKVGYKNGEYILNPTVTDLKDSQLELVVAGTANAVLMVESEAELLSEEVMLGAVTFGHREMQKVINIINELAVEAGTKPSDWVAPAKNDGMIAALKEAVGDQLASAFQVRDKLQRRDAISAIKKDVLGALAPRATIEGWAAGDLAKEFGELEYQTMRGSVLSTKVRIDGRALDTVRPISAKAGVLPRTHGSALFTRGETQAIVITTLGTARDGQVIDAVSGEYKENFLFHYNFPPYSVGECGRFGAPKRREIGHGRLAKRGVLAVMPSLEEFPYTIRVVSEITESNGSSSMASVCGSSLALMDAGVPIKAPVAGIAMGLVKEGNDFVVLSDILGDEDHLGDMDFKVAGTAEGVSALQMDIKIEGITEEIMKQALQQAKAGRLHILGEMAHALTTPRQELSDYAPRLLTIKIHPDKIREVIGKGGSTIQAITKETGTQIDIQDDGTIIIASVNAIAAQAAKSRIEQITSDVEPGRIYEGKVAKIMDFGAFVTILPGKDGLVHVSQISSERVEKVGDKLKEGDLVRVKVLEVDKQGRIRLSIKAVEEGEGVPASAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFRAL_MOUSE
Sequence: MLVFIFLAVTLSSENESSSQTNDCAHLIQKCLIDANGCEQSWRSMEDTCLTPGDSCKINNSLHCNLSIQALVEKNFQFKECLCMDDLHCTVNKLFGKKCTNKTDNMEKDNKDKWNLTTTPFYHGFKQMQSCLEVTEACVGDVVCNAQLALYLKACSANGNLCDVKHCQAAIRFFYQNMPFNTAQMLAFCDCAQSDIPCQQSKETLHSKPCALNIVPPPTCLSVIHTCRNDELCRTHYRTFQTECWPHITGKCHEDETCISMLGKQDLTCSGSESCRAAFLGTFGTVLQVPCACRGVTQAEEHVCMIFQHMLHSKSCFNYPTPNVKDISSYEKKNSKEITLTGFNSFFNGELLYVVVCMAVTCGILFLVMLKLRIQSEKRDPSSIEIAGGVIIQ
What is the function of this protein?
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PubMed:28953886, PubMed:28846099, PubMed:28846097, PubMed:28846098).  Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways (PubMed:28846098, PubMed:28846099).
What are the official names of this protein?
GDNF family receptor alpha-like.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Extracellular side.
Protein: DTD_ALISL
Sequence: MIALIQRVSEASVRVDGEITGEINQGLLILLGVEREDDEAKAKRLVERVLTYRIFEDDEGKMNLNVQQVNGSVLVVSQFTLPADTKKGTRPGFSKGANPIDAERLYDHFSDLCDEKLTTQRGRFAADMKVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKP_SALCH
Sequence: MKKWLLAAGLGLAMVTSAQAADKIAIVNMGNLFQQVAQKTGVSNTLENEFKGRAAELQKMETDLQSKMQRLQSMKAGSDRTKLEKDVMSQRQTFAQKAQAFEKDRARRSNEERNKLVTRIQTAVKKVANDQSIDLVVDANTVAYNSSDVKDITADVLKQVK
What is the function of this protein?
Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.
What are the official names of this protein?
Chaperone protein Skp.
What is the protein family that this protein belongs to?
Belongs to the Skp family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PDXH_XANAC
Sequence: MTDLYAEALATFAALYAEAQNSAELEASAMTVATANVDGRPSARTVLLKAFDARGFVFYTHLDSAKGRDLQTHPQAALLFLWRSLREAGIQVRIEGGVQLVSADESDAYFASRPRMSQIGAWASRQSQALGSREEFDAAIAKVEATFAGREVPRPDGWGGFRVVPQAFEFWYGAKFRLHERWRYEADAASHWSKRMLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RPRD2_HUMAN
Sequence: MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVKDPSVSKSVERIFKIWEDRNVYPEEMIVALREALSTTFKTQKQLKENLNKQPNKQWKKSQTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCLKDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVANAYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPTMESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENISKASSCTPVPVTMTATPPLPKPVNTSLSPSPALALPNLANVDLAKISSILSSLTSVMKNTGVSPASRPSPGTPTSPSNLTSGLKTPAPATTTSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTGNPVPASEAASQSTSASPANTTVSTIKGRNLPSSAQPFIPKSFNYSPNSSTSEVSSTSASKASIGQSPGLPSTTFKLPSNSLGFTATHNTSPAAPPTEVTICQSSEVSKPKLESESTSPSLEMKIHNFLKGNPGFSGLNLNIPILSSLGSSAPSESHPSDFQRGPTSTSIDNIDGTPVRDERSGTPTQDEMMDKPTSSSVDTMSLLSKIISPGSSTPSSTRSPPPGRDESYPRELSNSVSTYRPFGLGSESPYKQPSDGMERPSSLMDSSQEKFYPDTSFQEDEDYRDFEYSGPPPSAMMNLEKKPAKSILKSSKLSDTTEYQPILSSYSHRAQEFGVKSAFPPSVRALLDSSENCDRLSSSPGLFGAFSVRGNEPGSDRSPSPSKNDSFFTPDSNHNSLSQSTTGHLSLPQKQYPDSPHPVPHRSLFSPQNTLAAPTGHPPTSGVEKVLASTISTTSTIEFKNMLKNASRKPSDDKHFGQAPSKGTPSDGVSLSNLTQPSLTATDQQQQEEHYRIETRVSSSCLDLPDSTEEKGAPIETLGYHSASNRRMSGEPIQTVESIRVPGKGNRGHGREASRVGWFDLSTSGSSFDNGPSSASELASLGGGGSGGLTGFKTAPYKERAPQFQESVGSFRSNSFNSTFEHHLPPSPLEHGTPFQREPVGPSSAPPVPPKDHGGIFSRDAPTHLPSVDLSNPFTKEAALAHAAPPPPPGEHSGIPFPTPPPPPPPGEHSSSGGSGVPFSTPPPPPPPVDHSGVVPFPAPPLAEHGVAGAVAVFPKDHSSLLQGTLAEHFGVLPGPRDHGGPTQRDLNGPGLSRVRESLTLPSHSLEHLGPPHGGGGGGGSNSSSGPPLGPSHRDTISRSGIILRSPRPDFRPREPFLSRDPFHSLKRPRPPFARGPPFFAPKRPFFPPRY
What are the official names of this protein?
Regulation of nuclear pre-mRNA domain-containing protein 2.
Protein: EX7S_BURL3
Sequence: MAKTASPGATPPGNGTEPLPDNYEMALAELETLVARMEGGALSLEDSLTAYRRGATLVAFCQQQLEKVEQQVRVLDGATLKPLSSGTAATDGEDDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT1_CLOBL
Sequence: MEKLQNRILQEGHALSETVLKVDSFLNHQVDPDLMYEIGTYFKNYFKEHKITKIFTIESSGIAPAVMTAMQMNLPMVILKKQASKILNGDVYQTTVHSFTKGLDYELTLSKKYINKEDNILIIDDFLANGEAALGAARLVQESGAKVAGMGIVIEKSFQPGRKMLEEKGYDVYSLARIAKLEKGLIEFVK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase 1, XPRTase 1.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFNA_METKA
Sequence: MILQRDSDYSDGTVLGSMCTEPHPVAAEAFVAGLHVNLGDPYLFPNAYRAERECIGWLAETLLDHPAPEEAEGSIVSGGTEANILAAYAAREVTGGREIIVPATRHFSFEKAARMLRMKLVEAPLRSDYTVDVDAVQDLISRDTALIVGIVGTTETGSVDDIEALSDVAEDHGVPLHVDAAFGGFTAPFLREEYPLPRFGFDLEAVVSVTVDPHKMGLVPPPAGGIVFRDDEFPKAIEVYAPYLSGGGASQYTITGTRPGAPVLALYANILELGEEGYRRIAFRCYEETLKVAEKARELGLELAVDPPHLNLVNIRLPDRGTAERLLRESEREGWKISVSTKPLGVRIVMMPHLDAETVSRFLELVARVLGG
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.