PharMolix/UniProtQA huggingface dataset:
Protein: UGPC_SHISS
Sequence: MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKSTLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLKIRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDEPLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGTPVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIVLPLNGGYRQYAGRKMTLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGSTLWLHLAENQLHLFDGETGQRV
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TCF7_HUMAN
Sequence: MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTETNWPRELKDGNGQESLSMSSSSSPA
What is the function of this protein?
Transcriptional activator involved in T-cell lymphocyte differentiation.  Necessary for the survival of CD4(+) CD8(+) immature thymocytes.  Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role.  Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene.  Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages (By similarity).  Required for the development of natural killer receptor-positive lymphoid tissue inducer T-cells (By similarity).  TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes.
What are the official names of this protein?
Transcription factor 7, TCF-7, T-cell-specific transcription factor 1, T-cell factor 1, TCF-1.
What is the protein family that this protein belongs to?
Belongs to the TCF/LEF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS16_PHYMT
Sequence: MSVKIRLQRFGKHKKPFYRVVAINSKNSRDGKFLEILGTYEPLLGNINLNTKNIEKWLFYGAVPTLTVKNLINKQNKNNKS
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: FLGG_BUCAI
Sequence: MIPSLWISKTGLDAQQINMNIISNNLANVSTNGFKRSRAVFEDLMYQTIREAGTNSSLETTLPSGLQLGTGVRPVSTERIHTQGNLSKTDASKDVAINGSGFFQVQLPDGNIAYTRDGSFQLDQNGQLVTNSGFPIIPEINIPSNSTNINIARDGVISVVVQGQTQPVLLGQLNLINFVNNSGLESLGENLYQETQASGSPIETTPGLNGTGVLYQGYVETSNVNVAEELVNMIQTQRAYEINSKSISTSDQMLQKLSQL
What are the official names of this protein?
Flagellar basal-body rod protein FlgG, Distal rod protein.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: DNAK_ANASL
Sequence: QAVMNPENTFYSVKRIINEPTAASLAYGFDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: GMHA_SALEP
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYDYIFSRYVEAVGREGDVLLGISTSGNSGNVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_VIBCH
Sequence: MSFAILGFIALGGAVGACARFLVSEICVTLFGRGFPIGTLTVNVVGSFIMGVLIACVENEWLSPYPWKQVIGLGFLGALTTFSTFSMDNVLLMQQGAFFKMGANVLLNVILSISAAWIGFHWLMKS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CSPL5_ARATH
Sequence: MTSNGEGGEVVAKRRRKGIKELVQVALRGGCLAASATAMAVMLTATEEGVADIYGFKLTLSSNWSFSPSYQYVVGACAGTVLYSLLQLCLGVYRLVTGSPITPSRFQAWLCFTSDQLFCYLMMSAGSAGSGVTNLNKTGIRHTPLPDFCKTLSSFCNHVALSLLLVFLSFIFLASSSFFTVLVLSTP
What are the official names of this protein?
CASP-like protein 3A2, AtCASPL3A2.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TMCAL_CLOBK
Sequence: MNVSAIVVEYNPMHNGHLYHIEKTKKLTNCDALVCIMSGNFVQRGFPSILDKWTKANMAISNGVDLVIELPTLYSLSSAEFFSFGAVSILDSLNIINSICFGSEIGNINVLQDIATTLLEEPLEYKILLKNYLDKGISFAKARNLALVELNRDNKIMSENISKILSLSNNILGIEYLKSLLLLNSSIKPFTITREGADYKDENLHEEYSSASSIRKYLKENKNINILKDFLPLEGFLEFKRLITKGYNFSMEDSMINYIRYKYISGYKNLHNLIDVSEGLDNRIYKSLEKSFTYDSLVGEIKSKRYAYSRIGRILCQYFIGFENYDLNSLLKSTPNYMRVLASNERGLKVLKEVKKHSSINIYTKLPKNTNTLLSLDIKATNAYSLLNNNIRFNEDYFRSPTIIKNTIY
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_PANGI
Sequence: MTIALGKFTEDEKDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENLYFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ATPA_STRP3
Sequence: MAINAQEISALIKKQIENFQPNFDVTETGIVTYIGDGIARARGLDNAMSGELLEFENGAYGMAQNLESNDVGIIILGDFSAIREGDVVKRTGKIMEVPVGEALIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGALDYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNVISITDGQIFLQENLFNSGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRLDLASYRELEAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPVDDILAFEEALYDYFDVHYNDLFETIRTTKDLPEEAALDAAIKAFKEHSNFKS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FEN1_XIPMA
Sequence: MGIHGLAKLIADHAPGAIKEQDIKNYFGRKIAIDASMCIYQFLIAVRQDGNVLQSEDGETTSHLMGMFYRTIRMLENGIKPVYVFDGKPPQLKSAELEKRGERRAEAEKMLAKAQELGEQENIDKFSKRLVKVTKQHNDDCKKLLTLMGVPYIEAPCEAEASCAALVKEGKVFATATEDMDGLTFGTNVLLRHLTASEAKKLPVQEFHFNRILQDIGLTSEQFIDLCILLGCDYCGTIKGIGPKRAIDLIRQHGSIEEILENIDTSKHPAPEDWLYKEARNLFLKPEVVDSSTVDLKWREPDEEALIQFMCSEKQFSEDRIRNGCKKMMKSRQGSTQGRLDSFFSVTGSLSSKRKEPETKGSAKKKQKTGATPGKFRKGK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: KDPC_STRAW
Sequence: MNNSVTNTARLLWAGLRSLLVLTVVTGVLYPLAVTGVAQGLFSDQANGSEIKADGKVVGSSLIGQAYNLPLKKGQETPEPDLKWFQGRPANGLGTNSVNTQYSLILSGATNRSGDNADLIKWVKDAKAAVVKDNSTADHKVKPSDVPADAVTSSGSGLDPDISPEYADLQVHRIAEQNHLAVAPVQKLVDEHTDGRTLGFIGEPRVNVLELNIALKELVATS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ALG11_NEUCR
Sequence: MANGLFTYVAISLFTIGPLLALFIPFVWRLVGSSLGWYLRRKTDGRRCHILEVVEADERKYRDSKSAKGRKAEKEDRDTFNNTEATGTSDGKVYDKDWDGIVGFFHPFCNAGGGGERVLWAAIRATQKRWPKAKCVVYTGDHDVSKEAILSRVEQRFNIHLHPPTVNFLYLSTRRWVLASTWPYFTLAGQSFGSLIMAWDAFSLLVPDIFVDTMGYAFALGFSRFLFRDVPTAAYVHYPTISTDMLESLDPASAVGSQGVNAGKGTGAKGRAKKIYWQLFARLYSLMGASVDVVMTNSTWTQAHIEKLWGPVRNLTGAVPGIKSKVNPIAVVYPPVAVEELEQEVEVSPESEKRRENVLLYIAQFRPEKNHQLIVQAFAEFLKSGSEAARDAKLVLVGSVRDDYDSKRVYKLRLLVNELHIKDRVEFHLDASWPDILEWLRRASVGVNGMWNEHFGIGVVEYQAAGLISVVHDSGGPKLDIVVEVDGEPTGFHATTSKEFAEGFEKALSLPNPYAVRLRARKSAKRFTEEEFARRWIEQLEKCVAIKAVEKPKSRQ
What is the function of this protein?
Required for N-linked oligosaccharide assembly.  Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Alpha-1,2-mannosyltransferase alg-11, Asparagine-linked glycosylation protein 11, Glycolipid 2-alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: IDER_MYCTO
Sequence: MNELVDTTEMYLRTIYDLEEEGVTPLRARIAERLDQSGPTVSQTVSRMERDGLLRVAGDRHLELTEKGRALAIAVMRKHRLAERLLVDVIGLPWEEVHAEACRWEHVMSEDVERRLVKVLNNPTTSPFGNPIPGLVELGVGPEPGADDANLVRLTELPAGSPVAVVVRQLTEHVQGDIDLITRLKDAGVVPNARVTVETTPGGGVTIVIPGHENVTLPHEMAHAVKVEKV
What is the function of this protein?
Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism.  Acts as a repressor of siderophore biosynthesis and as a positive modulator of iron storage.  Also regulates expression of transporters, proteins involved in siderophore synthesis, iron storage and transcriptional regulators (By similarity).
What are the official names of this protein?
Iron-dependent repressor IdeR.
What is the protein family that this protein belongs to?
Belongs to the DtxR/MntR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTL_SCHPO
Sequence: MSSTKKDIKVYVNYRDEYAEPKIISALKNSGKELTFTNSAKEANFQWAQYEDIDFDEVYKNPKTKLCCSYVIRKALIRKEYLWRTVITYLAKHPDSILSKSVPEAYSLELDYAEFLDDSLMEAYELRQELEENATKNISEKQWYILKPSMCDRAQGIRLFSTIEELQAIFDSFDDEESESEEAGLEEKGDITVAFNNKIVISQIRNFLVQKYISKPLLLDHRKFHIRAYVLATGALSVYLFNEMLCLLARDKYKKPTPDPDLLFSHLSNTCLQGDNVEQSSIRDFWNTSIENKDDIFKSILNIIGDVFEAAATTQGIHFQPLENCFEIFGVDFLVDCESQVYLLEVNSYPDFKQTGKNLSNIIENLFSAVVETAIIPFFESSTKRNVDSKLTLAKKLQLFGFR
What is the function of this protein?
Probable tubulin--tyrosine ligase.
What are the official names of this protein?
Probable tubulin--tyrosine ligase C12B10.04.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACCD_VIBVU
Sequence: MSWLEKILEKSNIVSSRKASIPEGVWTKCTSCEQVLYHAELERNLEVCPKCNHHMRMKARRRLETFLDEGNRVELGGELEPQDKLKFKDSKRYKERIAAAQKSSGEKDALVAMKGELLGMPIVACAFEFSFMGGSMGSVVGARFVRAVEAAMENNCALVCFSASGGARMQEALMSLMQMAKTSAALERLSAKGLPFISVMTDPTMGGVSASLAMLGDINIGEPKALIGFAGRRVIEQTVREDLPEGFQRSEFLLEHGAIDMIVDRREMRQRVGGLIAKLTNHKSPLVVSVNDSPNEAAYSVPEANEKG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IQD14_ARATH
Sequence: MVKKGSWFSAIKRVFTPHSKEKLANEPERKSGKEKKKKGFGKLRHGETNSFLPIFREPSSIEKILGEAERDHNLVFRPPTPDRPNPYSASPPPRPASPRVASPRPTSPRVASPRVPSPRAEVPRTLSPKPPSPRAEVPRSLSPKPPSPRADLPRSLSPKPFDRSKPSSASANAPPTLRPASTRVPSQRITPHSVPSPRPSSPRGASPQAISSKPPSPRAEPPTLDTPRPPSPRAASLRADPPRLDAARPTTPRPPSPLADAPRLDAPRPTTPKPPSPRSDPPRLDAPRPTTPKPPSPRSVSPRAVQRREIVYRPEPTLPVQHASATKIQGAFRGYMARKSFRALKGLVRLQGVVRGYSVKRQTINAMKYMQQVVRVQSQIQSRRIKMLENQAQVEKDEAKWAASEAGNDNWDDSVLTKEERDSRSQRKTDAIIKRERSMAYAYSRKLWKNSPKSTQDNRSFPQWWNWVDRQNPLASPAPSYSQPQRDFRLTPSRLCPSPLSQSSKQHHIRLDNHFDTSTPRSSRSTFHTPSRPIHTGTSRYSRGRLRGQDSPFKDDDSLTSCPPFPSYMAPTVSAKAKVRPNSNPKERVMGTPVSEKRRMSYPPTQDTFRWNKGSLVMSNSSSHRGPGSPGGVVLEKHKTLKSVGNLSIGSTASMATTVGRKEFNRFV
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (PubMed:28115582).  Regulates cell and organ shapes (prevents twisting) in aerial parts probably by regulating transverse microtubules (MT) arrays alignment (PubMed:28115582).  Regulates the formation of oval xylem secondary cell-wall deposition pits through microtubule-dependent lateral inhibition of Rho GTPase domains, thus confining the area of active ROP domains within the lattice of the cortical microtubules (PubMed:28803875).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 14, AtIQD14.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton.
Protein: PAIP2_HUMAN
Sequence: MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI
What is the function of this protein?
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs.  Its inhibitory activity on translation is mediated via its action on PABPC1.  Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1.  Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
What are the official names of this protein?
Polyadenylate-binding protein-interacting protein 2, PABP-interacting protein 2, PAIP-2, Poly(A)-binding protein-interacting protein 2.
What is the protein family that this protein belongs to?
Belongs to the PAIP2 family.
Protein: MCEL_VACCC
Sequence: MDANVVSSSTIATYIDALAKNASELEQRSTAYEINNELELVFIKPPLITLTNVVNISTIQESFIRFTVTNKEGVKIRTKIPLSKVHGLDVKNVQLVDAIDNIVWEKKSLVTENRLHKECLLRLSTEERHIFLDYKKYGSSIRLELVNLIQAKTKNFTIDFKLKYFLGSGAQSKSSLLHAINHPKSRPNTSLEIEFTPRDNEKVPYDELIKELTTLSRHIFMASPENVILSPPINAPIKTFMLPKQDIVGLDLENLYAVTKTDGIPITIRVTSNGLYCYFTHLGYIIRYPVKRIIDSEVVVFGEAVKDKNWTVYLIKLIEPVNAINDRLEESKYVESKLVDICDRIVFKSKKYEGPFTTTSEVVDMLSTYLPKQPEGVILFYSKGPKSNIDFKIKKENTIDQTANVVFRYMSSEPIIFGESSIFVEYKKFSNDKGFPKEYGSGKIVLYNGVNYLNNIYCLEYINTHNEVGIKSVVVPIKFIAEFLVNGEILKPRIDKTMKYINSEDYYGNQHNIIVEHLRDQSIKIGDIFNEDKLSDVGHQYANNDKFRLNPEVSYFTNKRTRGPLGILSNYVKTLLISMYCSKTFLDDSNKRKVLAIDFGNGADLEKYFYGEIALLVATDPDADAIARGNERYNKLNSGIKTKYYKFDYIQETIRSDTFVSSVREVFYFGKFNIIDWQFAIHYSFHPRHYATVMNNLSELTASGGKVLITTMDGDKLSKLTDKKTFIIHKNLPSSENYMSVEKIADDRIVVYNPSTMSTPMTEYIIKKNDIVRVFNEYGFVLVDNVDFATIIERSKKFINGASTMEDRPSTKNFFELNRGAIKCEGLDVEDLLSYYVVYVFSKR
What is the function of this protein?
Catalytic subunit of the mRNA capping enzyme which catalyzes three enzymatic reactions: the 5' triphosphate end of the pre-mRNA is hydrolyzed to a diphosphate by RNA 5' triphosphatase; the diphosphate RNA end is capped with GMP by RNA guanylyltransferase and the GpppN cap is methylated by RNA (guanine-N7) methyltransferase.  Heterodimeric mRNA capping enzyme catalyzes the linkage of a N7-methyl-guanosine moiety to the first transcribed nucleotide (cap 0 structure), whereas the methyltransferase OPG102 is responsible for a second methylation at the 2'-O position of the ribose (cap 1 structure).  Also involved in early viral gene transcription termination and intermediate viral gene transcription initiation.  Early gene transcription termination requires the termination factor VTF, the DNA-dependent ATPase NPH-I/OPG123 and the RAP94/OPG109 subunit of the viral RNA polymerase, as well as the presence of a specific termination motif.  Binds, together with RAP94/OPG109, to the termination motif 5'-UUUUUNU-3' in the nascent early mRNA.
What are the official names of this protein?
mRNA-capping enzyme catalytic subunit, Virus termination factor large subunit, VTF large subunit, mRNA-capping enzyme 97 kDa subunit, mRNA-capping enzyme D1 subunit, mRNA-capping enzyme large subunit.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Protein: PTPA2_SCHPO
Sequence: MLSREEQNRCFVPVRRILDNEDLKLFKEGDAYKLIDSFICDLDEAVKDKPISASIPQSSSIEHVLNILDRVGEIKQENPAIDNMGSRFGNPAFQSFYDQVYIETPKLHQVFGIEHNAAMEAGRYFYESFGNRKRIDYGSGHELYFMSWLLILKQLGIFTKNDYPALVVRVFVKYVELMRSLQIFYTLEPAGSHGVWGLDDFHFLPFLFGAAQLVNHKYLRPKHVRDPEILEMCRADYMYLGYVYFLNKLKPSVSLRFHSPMIDDISAVKTWSKVNEGMIKMYRAEVLGKLPIMQHYLFGHLIPASPGMSPAPQDGDDSEVTHVHSHYADCCGIKIPSAISAAKNNGSRIPFD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 2, Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR5_CERAS
Sequence: MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPRIIFTTSHRERLHYTCSSHFPYSQYQFWKNFHTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CBY2_BOVIN
Sequence: MSPLECSECFGDQLLHRTYTWHLTLHSRPNFTRKRDTRSESLEIPINVVLPQRGTAEPFLRLHNLYPTPRCARQAALPRLSRRVVSQHSYPLNRFSSVPLDPMERPTSQADLELDYNPPRVQLSDEMFVFQDGRWVSENCRLQSPYFSPSSSFHHKLHHKRLAKECLLQENKTLREENRALREENRMLRKENKILQVFWEEHQAALGRDDSRASSPLLHKDNASSLEAMKKETALQAHRGRENSTLQLLREENRALQQLLEQRKAYWAQPDEKAASTEEIKPISSPHEEPHGLLPDPGPGLPSPFEEPKGLPAPPDDSKTLRALREMVSTLSAQPGEEVGKGGPGLPDGSQSLELLREMNQALQALREENQSLQVLRDENRLLQEENRALHALREEHRLFQEENKALWENNKLKLQQKLVIDTVTEVTARMEMLIEELYAFMPAKSKDPKKPSRV
What are the official names of this protein?
Protein chibby homolog 2, Spermatid-associated protein.
What is the protein family that this protein belongs to?
Belongs to the chibby family. SPERT subfamily.