PharMolix/UniProtQA huggingface dataset:
Protein: RF1_LEVBA
Sequence: MDEMFDKLQAVADRYDELNELISDPEVIADTQRFMALSKEEGELRETVDKYHQYQDVTQQIADDDEMLHDKLDADMESMIKDELKELTAQKAALEEDIKVLLLPKDPNDDKNIIMEIHGAAGGDEASLFAADLFSMYSKYAERQGWQIEVVDENATEVGGFKEIVMMITGNKVYSKLKYENGAHRVQRVPVTESAGRVHTSTATVGVMPEEEDVDIDIDPKDIRTDVYRSSGAGGQHINKTSSAVRMTHLPTGIVVAMQDERSQQQNRAKAMQILRARVYDYYKQQEESAYNAERKSAVGTGDRSERIRTYNYPQNRVTDHRIGLTLNKLDRIMNGELDDIIDALIVSDQAAKLEDLKNNG
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BL1S2_DICDI
Sequence: MSETTPNNTSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNHNNNNNTNNNNIDTFSQKASNDIVKPILPVTEDLQNSTKEMFTKVSSYIKSELATTVSDYNLLIQMNNITSSKYQDMTNVTKGLSVFMGDLKIKYEEFQPYFDKINELDKNVTDLEKTVQLLDEYTKRLEQKVKNIDKSSLLPTKQIQPPQPIPQQQPAQPAQPTQPTQPAQQPSQVSTETKPQENIENK
What is the function of this protein?
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).  May also participate in the coupling of lysosomes to microtubule plus-end-directed kinesin motor.  May also play a role in intracellular vesicle trafficking.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit 2, BLOC-1 subunit 2.
What is the protein family that this protein belongs to?
Belongs to the BLOC1S2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Lysosome membrane.
Protein: DIVIB_STAPH
Sequence: MTKEIPKINNEYLKEKRKKQRIQQRRVQRMIVGILVVIVLLILVYMFTPISHIKSADIKGNHYVSKQDILKELDIQNHPRIYAYSSDDAETRLKQNELIDEVTIEKGLFNPIEVNVKEHTIIAITTEKSRVVPMIENGKVLKDYKQEVPNEAPYIEGFKGAEKRNLIDALQKMDRTTRAQISEIVSAPQKDQPHLIKLFMRDGIEVVGNTNTIAEKLKYYPSMSQALEKDETGKLKKSGFIDLSVGATFIPYDNVNNGQTSSASAKEVQSGTASEDKAKDDLQKALNKIKDEESSE
What is the function of this protein?
Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex.
What are the official names of this protein?
Cell division protein DivIB.
What is the protein family that this protein belongs to?
Belongs to the FtsQ/DivIB family. DivIB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: GST_MUSDO
Sequence: MADEAPAAPPAEGEAPAAPAEGEAPPPAEGEAPPAEPVKNTYTLFYFNVKALAEPLRYLFAYGGIEYEDVRVTRDEWPALKPTMPMGQMPVLEVNGKRVHQSISMARFLAKTVGLCGATPWEDLQVDIVVDTINDFRLKIAVVSYEPEDEIKEKKLVTLNNEVIPFYLEKLEQTVKDNDGHLALNKLTWADVYFAGILDYMNYMVKRDILEQYPALRGVVDSVNALEPIKAWIEKRPQTEV
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase, GST class-sigma.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Sigma family.
Protein: NUOB_XYLFT
Sequence: MGVIQAIDRLMTNPIPDGQVDDILRPQGESPLLQKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGAARLDLDRYGIVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGILQLQKKIWRTKTIAG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KADA_SACS2
Sequence: MKIGIVTGIPGVGKTTVLSFADKILTEKGISHKIVNYGDYMLNTALKEGYVKSRDEIRKLQIEKQRELQALAARRIVEDLSLLGDEGIGLIDTHAVIRTPAGYLPGLPRHVIEVLSPKVIFLLEADPKIILERQKRDSSRARTDYSDTAVINEVIQFARYSAMASAVLVGASVKVVVNQEGDPSIAASEIINSLM
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIS_METKA
Sequence: MDVKTLVGEYYASLPSGVLREFVEDPSSREWAYTFLKGRDIVFTRKRRLDEVSGFLELYHSTGKFKNPKSWEGLLGWDLVIDVDAELPEEPEAFLKSLGRLLKDVVIACDELRRALGFPRPDVVNFSGSKGFHVRYFDSTVRRWLRWDLHERRGIKPGEIIQRVGRGVVWLAREGFVAGDRVRALREGLLDDSMYDLKRLIRCVGSMNVKSLLPAVPVWSREGGRWVDFRDEVLGMNDLELGCLVAHRTLTWPGRGGLGVVLSRVLDLDTDADPEDPSDFVEVWGNVMSVLGELKP
What is the function of this protein?
Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  The small subunit contains the primase catalytic core and has DNA synthesis activity on its own.  Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase small subunit PriS.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase small subunit family.
Protein: CHI1_YERET
Sequence: MEKEEKSNLIYDKDPGYVWDNKNECEGAAEETYQELNYEPSISADKLTWTPTRLAKTVFNTYEDDDDFNVLCYFTDWSQYDPRIINKEIRDTGGRSADILRLNTPDGRPFKRLIYSFGGLIGDKKYSADGNASIAVRLGVATDPDDAIANHKGKTIPVDPDGAVLASINCGFTKWEAGDANERYNQEKAKGLLGGFRLLHEADKELEFSLSIGGWSMSGLFSEIAKDEILRTNFVEGIKDFFQRFPMFSHLDIDWEYPGSIGAGNPNSPDDGANFAILIQQITDAKISNLKGISIASSADPAKIDAANIPALMDAGVTGINLMTYDFFTLGDGKLSHHTNIYRDPSDVYSKYSIDDAVTHLIDEKKVDPKAIFIGYAGYTRNAKNATITTSIPSEEALKGTYTDANQTLGSFEYSVLEWTDIICHYMDFEKGEGRNGYKLVHDKVAKADYLYSEATKVFISLDTPRSVRDKGRYVKDKGLGGLFIWSGDQDNGILTNAAHEGLKRRIKNKVIDMTPFYLDSDEELPTYTEPAEPQCEACNIK
What is the function of this protein?
Part of an orally active toxin complex (TC) with strong insecticidal effects on larvae of the Coleoptera Costelytra zealandica, Acrossidius tasmania and Adoryphorus couloni and some Lepidoptera larvae (PubMed:21278295).  The TC has an endochitinase activity (PubMed:21278295, PubMed:22158901) (Probable).  This subunit might aid infection by degradation of the larval peritrophic membrane (Probable).
What are the official names of this protein?
Chitinase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted when grown at 25 degrees Celsius or less, but not when grown at 30 or 37 degrees Celsius.
Protein: VATF_METAC
Sequence: MELAVIGKSEFVTGFRLAGIRKVYEIVDVPSSESAVKSVLEDKSIGILVMHNDDISNLPEILRRNLNESVQPTVVALGGTGEGSMSLRDKIKQAVGVDLWK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: DUS_RICPR
Sequence: MIKIGNIELSSNVILAPMSDVTDLEFRKLVKRFGAGLVVSEMIASRAMIMKSRQSMQKCAIMHDDPTSACVQLAGCEPDVIAEAAKMNEDMGAKIIDLNFGCPAKKVVGGYAGSALMRDEQLAAKIFEATVKAVKIPVTVKMRIGWDDNTRNAPTLAKIAANSGVQMVTVHGRTRCQFYSGNANWDFIRTVKEAVKIPVIANGDITNFAKAKEALQRSGADGIMVGRGVYGKPWLISQIAYYLKTGKEKPAPSIAEQLDIITKHYDAIIDYYGKSVGVPIARKHIIWYSNGLPSSAEFRCTVNLMKDPIAVKEKIAEFYMSVMDANK
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.
What are the official names of this protein?
Probable tRNA-dihydrouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: NUOB_AKKM8
Sequence: MVTTNEPNIYETGVLDSNAEGNFVYTTLDAAINWIRKNSLWPMPMGLSCCAIEFMAVACSRYDLSRFGSEVTRFSPRQADVMIVAGTVTYKMALAVRRIWDQMPEPKWCIAMGACASTGGMFRSYSVLQGVDKILPVDVYISGCPPRPEAILEALLTLRKKLDTQQPARTFFKKEEPREANAPVPVNTEMPLE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RECO_BRUSU
Sequence: MEWRDEGVILGTRRHGETSAIVEVMTCGHGRHMGMVRGGRSRRMQPLLQPGNHVDVSWWARLDEHMGTFTIEPLSFAAARLIETPVALYGIQLAAAHLRLLPERDPHRGLYETLRLIIEHFDDPLAAGELLLRFEVMMLEELGFGLDLKECAATGRKDDLIYVSPKSGRAVCREAGAPWAEKLLSLPSFVNDTALRASCYDDLDRAFTMTGYFLMRHVWEPRAQTPPDSRSGFLNAVGRAINLSQAS
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: LPXB_RICTY
Sequence: MKKIYFIAGEMSGDFIGGHIIQNLKSNEGLEFTGIGGQYMEEAGNFKSLFTITAINFIGFIEIIPHLLKIKKLIDKTVENIINSKVDLLITIDSPGFTYRVAKRVRKFLPNLKIIHIVAPSVWAYKAGRAVDYAKIYDCLFALLPFEPPYFTKVGLDCRYIGHPILEQEFYRDKIALRKEFKIDDNESILCVTFGTRKGEILRHLPIFITAIQKISKDYKNLRIIFPLVHPDHEAIIKPFLENVQFNYLFLSSERLKAYAVSDLALAKSGTNTLEISASGTPMVVAYKVNIISFFIIMFLIKIKYVSLINIMAGSAIIPEFIQFNCRANLISNKLKELLSNSQKRDNQVVESQKILQKLRFASDRSPSYIAAKIIKQEFL
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: MYOT2_LOCMI
Sequence: TSSLFPHPRL
What are the official names of this protein?
Myotropin-2, Scg-MT-2.
Protein: FPG_CORDI
Sequence: MPELPEVEVVRRGLTPYVLGATITDVAVEHPRSIRTIEGGAAELIGSLQGREVTRIGRRGKFLWFELTGHGDYACGFPQQGLLVHLGMSGQMLIKTQNSALHPHRRIRTTIVRSDAQECFELWFVDQRTFGYWAPTTFVETAHGCVPEQITHIARDLLDPQLKRENLARLIRKKNSEIKRVLLNQEIVSGIGNIYADEMLWAARIHPQTPASHLSVAQLSNLLEHGQRVMNAALDQGGTSFDSLYVNVNGQSGYFDVSLHAYGQQGQACDRCGSNIIREKFANRSSHFCPRCQLMH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LPXK_RICB8
Sequence: MIKLLYPKFWQKRNIIAYILFPISWIYQFLGFLRHVFVRPVILPAKVICVGNCSVGGTGKTQIVMYLANLLKTQNIDFVIVTKAYGSNLKEATIVKAEHSTLEVGDESVILAKHGTVIATKNIKQILPLIHELKPSIIIVDDFLQNPYFHKDITIVSVDRQRLFGNGFLIPAGPLREYPNRALSAADLVFLVGNNSGGIPVSLASYANKLIQAQIVASSDIDKNKNYFAFSGIGNPERFFLTLKNYGLNIVGYKIFPDHYNYLQEDLENLSLLAKTNNATLITTRKDYVKIGDSSDIIVCLDVKLSINNPNLLYEKIFKKD
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: DHLE_GEOSE
Sequence: MELFKYMETYDYEQVLFCQDKESGLKAIIAIHDTTLGPALGGTRMWMYNSEEEALEDALRLARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTVADMDIIYQETDYVTGISPEFGSSGNPSPATAYGVYRGMKAAAKEAFGSDSLEGKVVAVQGVGNVAYHLCRHLHEEGAKLIVTDINKEVVARAVEEFGAKAVDPNDIYGVECDIFAPCALGGIINDQTIPQLKAKVIAGSADNQLKEPRHGDIIHEMGIVYAPDYVINAGGVINVADELYGYNRERAMKKIEQIYDNIEKVFAIAKRDNIPTYVAADRMAEERIETMRKARSPFLQNGHHILSRRRAR
What is the function of this protein?
Catalyzes the reversible deamination of L-leucine to 4-methyl-2-oxopentanoate.
What are the official names of this protein?
Leucine dehydrogenase, LeuDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
Protein: RK23_SACOF
Sequence: MDGIKYAVFTEKSLRLLGKNQYTFNVESGFTKTEIKHWVELFFGVKVVAVNSHRLPGKGRRMGPILGHTMHYRRMIITLQPGYSIPLLDRETN
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBL_PHAVU
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHVHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFEAMDTLD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GGI1_STAHA
Sequence: MQKLAEAIAAAVSAGQDKDWGKMGTSIVGIVENGITVLGKIFGF
What is the function of this protein?
Has hemolytic activity and also inhibits the growth of gonococci.
What are the official names of this protein?
Antibacterial protein 1, Gonococcal growth inhibitor I.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal hemolytic protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_ACIAD
Sequence: MARFYRRRKFCRFTAENVAYIDYKDIDTLKQYITENGKIVPSRITGTKARYQRQLALAIKQARYLALIPYTDNHK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: XNI_YERPB
Sequence: MQIHLLIVDALNLIRRIHAVQGSPCVKACQHALQQLIQHSQPSHAVAVFDEDDRSDSWRHQCLPDYKAGRSPMPDNLQQEMPLIRQAFNELGVACWHSPGNEADDLAATLVVKVAGAGHQVTIVSTDKGYCQLLAPNVQIRDYFQKRWLDMPFVKQEFGVLPRQLPDYWGLAGISSSKIPGVAGVGAKTATLLLQQADTLEVLYQNLESIPEKWRKKLQQHQQMAFTCKQIATLKTDLLLSGNLQQLRLKK
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: ERF3B_MOUSE
Sequence: MDLGSSSDSAPDCWDQVDMEAPGSAPSGDGIAPAAMAAAEAAEAEAQRKHLSLAFSSQLNIHAKPFVPSVSAAEFVPSFLPGSAQPPAPTASSCDETCIGGAGEPEGKRMEWGAPVEPSKDGPLVSWEGSSSVVTMELSEPVVENGEVEMALEESWELKEVSEAKPEASLGDAGPPEESVKEVMEEKEEVRKSKSVSIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHSVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD
What is the function of this protein?
Involved in translation termination in response to the termination codons UAA, UAG and UGA.  May play a role as a potent stimulator of the release factor activity of ETF1.  Exhibits GTPase activity, which is ribosome- and ETF1-dependent.  May play a role in cell cycle progression.  Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity).
What are the official names of this protein?
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B, Eukaryotic peptide chain release factor subunit 3b, eRF3b, G1 to S phase transition protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. ERF3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_STRMU
Sequence: MNLLIMGLPGAGKGTQAAKIVEKFGLAHISTGDMFRAAMANQTEMGTLAKSFIDKGELVPDEVTNGIVKERLSESDITKKGFLLDGYPRTIEQAHALDEILSKLNLKLDGVINIDVDPACLVERLSGRIINRKTGETYHKVFNPPADYNEDDYYQREDDKPETVKRRLDVNIAQGHPIIEYYRNKGLVYDIEGNQDINLVFETIAKVLANLS
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_RICTY
Sequence: MIKFITLQNLMDYQVTLKLMEDYVNKVINYNEPEIVYLVEHSEVYTAGTNYKQEELLNYGDIPVIYTGRGGKFTFHGPGQRVIYPILNLALPNRHKDLKLYIKMLEEWIINSLNYFGIKGYLIKDKVGIWIKVSKGEFAKIAAIGVRVRKWITYHGVAINISTDLCKFNGIIPCGLESSLVTSLNQLGIYVEMFEFDKIIQTEFNKIFK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_STRA5
Sequence: MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYTTGEWLNRKFSLIDTGGIDDVDAPFMEQIKHQADIAMTEADVIVFVVSGKEGVTDADEYVSRILYKTNKPVILAVNKVDNPEMRNDIYDFYSLGLGDPYPLSSVHGIGTGDILDAIVENLPVEEENENPDIIRFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTNFVDSQGQEYTMIDTAGMRKSGKVYENTEKYSVMRSMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHETGKGIIIVVNKWDTIEKDNHTVSQWEADIRDNFQFLSYAPIIFVSAETKQRLHKLPDMIKRISESQNKRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVAVKPPTFVVFVNEEELMHFSYLRFLENQIREAFVFEGTPINLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PESC_DROWI
Sequence: MRRPKKYESGEATQYISRRAALRRLQLSLNDFRRLCILKGVYPREPKHRRRAQKGSSEIKILYHAKDIRFLLHESIVWTLRDYKIFAKKSGRDRAIKDFRNLKRRLALFPEIKLDHIVKERYPTFIDALKDLDDCLTLLFLFSTFPSLHLIPREQSALCRRLTIEFLHYVIASKSLRKVFISIKGYYFQAEIKGQKVTWIVPHYYPFKPQSRQDVDFKVMSIFVEFYTIMLGFVNFRLFHGLNLAYPPQFPSSVLQDNSETLQDESSFVSDRIAALNFELLRTDKLMEDEEELDIDMELLEQDGDSKRIIKMKQEAQEVARLRTLFKGLKFFINREVPREPLIILIRSFGGKVSWDASVFAGATFDESDETITHQIVDRPSLSTQYISRDYIQPQWVFDCINQRQLLPTNKYFMGEQLPPHLSPFVDSKRETYIPPEEKALHDPSLIETHVQSDDDDDDSDAEADNQEEEEIEQQLLDAQLQRAYQQETAEYKKYGGTDGVNEDEEDSVDDDDEEDEEEEEEEDVEQLDDKTKRLLEEKQKMKVESGKVHKVNKRQIRKAEVDEHRLQARMVKPRHRNLFRKLIREKQTKEKEEWLLRKKRRNIDADAKEAKKTAKREAKKAAAEAAAKALKMA
What is the function of this protein?
Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit.
What are the official names of this protein?
Pescadillo homolog.
What is the protein family that this protein belongs to?
Belongs to the pescadillo family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: LUKEV_STAA8
Sequence: MLAATLSVGLIAPLASPIQESRANTNIENIGDGAEVIKRTEDVSSKKWGVTQNVQFDFVKDKKYNKDALIVKMQGFINSRTSFSDVKGSGYELTKRMIWPFQYNIGLTTKDPNVSLINYLPKNKIETTDVGQTLGYNIGGNFQSAPSIGGNGSFNYSKTISYTQKSYVSEVDKQNSKSVKWGVKANEFVTPDGKKSAHDRYLFVQSPNGPTGSAREYFAPDNQLPPLVQSGFNPSFITTLSHEKGSSDTSEFEISYGRNLDITYATLFPRTGIYAERKHNAFVNRNFVVRYEVNWKTHEIKVKGHN
What is the function of this protein?
Part of a bi-component leucotoxin that acts by forming pores in the membrane of the target cells.  The activity of LukEv-LukDv to rabbit leukocytes is similar to that of the Panton-Valentine leucocidin (PVL).  LukEv-LukDv is hemolytic to rabbit red blood cells although the activity is only 8% of gamma-hemolysin.
What are the official names of this protein?
Leucotoxin LukEv, Variant of LukE.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTPX_ECO45
Sequence: MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGFGGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAPDINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVNTFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTHPPLDKRIEALRTGEYLK
What are the official names of this protein?
Protease HtpX, Heat shock protein HtpX.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.