PharMolix/UniProtQA huggingface dataset:
Protein: PROB_RHOOB
Sequence: MSATRRTVASAGSIVVKIGSSALTSLVGGLDVGRLDALADAIEARMRAGSDVVVVSSGAVGAGLAPLGLTKRPRDLATKQAAASVGQLALAHAWGTSFARYGRTVGQVLLTADDIARRAQHRNAQRTLDRLRALHAVAIVNENDTVATAELRFGDNDRLAALVAHLVGADALVLLSDVDGLYDGDPRKGNATLIPEVNSPEDLDGVVAGSGGALGTGGMASKLSAARLAADAGVPVLLAAASDAGAALRDASVGTAFAARPSRLSARKFWVRHAADEQGILHIDEGAVRAVVTRRRSLLPAGITAVSGRFYGGDVVSLLGPEERPVARGVVAYDSAEISDILGKSTQELPAEMQRPVVHADDLVPL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXR_XYLFM
Sequence: MTKPIRNVAVLGATGSIGAAALDVLARHPRQFHVSLLAAGQRVDALLALCHTYRPDHAVIGDATLYTTLRDGLNAAGLATKAYAGEAALAELVASTTCDTVVAAIVGAAGLHSTLAAARAGKRLLLANKESLVLAGMLLMREASISGAEIIPIDSEHNAIFQCLRSRTTNGVHRVTLTASGGPFRGHNRTMLAKITPTQAMAHPTWSMGPKISVDSATLMNKGLEVIEAHHLFGLPSEQIDVLVHPQSLVHSLVEFIDGSTLAQLSLPDMRTTLAVGLAWPERIGSGVPGLDLMKHNRLDFEHPDTETFSCLRLARDAMQTGGTAPAVLNAANEIAVSAFLQGRIGFLTIPALIEHALTTLPRYEADTLETLLTVDTETRRITHAALTHFPLPL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: RS16_GEOSW
Sequence: MAVRIRLKRMGAKKKPFYRIVVADSRSPRDGRFIETIGTYNPITEPAEIKIDEELALKWLQNGAKPSDTVRNLLSKQGILEKFHNLKYGK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: ACCA_LEGPA
Sequence: MTRQFLEFEQPIEELNQKIEALRMVGSDNEVNLSEEIARLEAKCSELTENIFSRLEPWQIAQMARHPLRPQTTDYIERIFTDFQELHGDRSYSSAPAIIGGMARLNGEPVMVLGHQKGKRTKEKVYRNFGMARPEEYRKALRLMRMAEKFKMPVVTFIDTAGAYPGIGAEERNQSEAIARNLFAMSRIKTPIVCIVTGEAGSGGALAIGVGDKIIMLQFSIYSVISPEGCASILWKDASKASEAARAMGITADRIFENELVDMVVPEPLGGAHRDVDEMASRLKRLLTSELQALKKVPLDQLIELRYQKFMAMGACD
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBP5_HUMAN
Sequence: MVLLTAVLLLLAAYAGPAQSLGSFVHCEPCDEKALSMCPPSPLGCELVKEPGCGCCMTCALAEGQSCGVYTERCAQGLRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVKIERDSREHEEPTTSEMAEETYSPKIFRPKHTRISELKAEAVKKDRRKKLTQSKFVGGAENTAHPRIISAPEMRQESEQGPCRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPGMEYVDGDFQCHTFDSSNVE
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.
What are the official names of this protein?
Insulin-like growth factor-binding protein 5, IBP-5, IGF-binding protein 5, IGFBP-5.
What are the subcellular locations of this protein?
Secreted.
Protein: COAX_MARMS
Sequence: MSVESRVLVVDAGNTSIKFTAFEGEQVLWVLRGDSCPAETDFAPQVIYFASVRSKEQSALLHADVQAAFPSSEWITLTSQATACCVRNAYIEPERLGIDRWLGVVAAHHLIKGNVVVVDAGTAIKVDVVNSEGAHLGGYIAPGLAMMTESLLSKTARIRFDSHEVVEGEGLPNSTARAVTEGCHEMALGFLERIHHLYPEFKWVVTGGDAQALLNRLGIALECFPNLVALGAKLVGDEQLRGNK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCNJ6_HUMAN
Sequence: MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENESKV
What is the function of this protein?
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors.  Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.  Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages.  The inward rectification is mainly due to the blockage of outward current by internal magnesium.
What are the official names of this protein?
G protein-activated inward rectifier potassium channel 2, GIRK-2, BIR1, Inward rectifier K(+) channel Kir3.2, KATP-2, Potassium channel, inwardly rectifying subfamily J member 6.
What is the protein family that this protein belongs to?
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CRGA_CORJK
Sequence: MPKSKVNSAEENYSSSSSADRRTPVKLNSSGTPRWYIVLMLALMLLGLAWLVVNYIAGPEIPFMRDLNAWNYLIGFALLIVGLLMTMGWK
What is the function of this protein?
Involved in cell division.
What are the official names of this protein?
Cell division protein CrgA.
What is the protein family that this protein belongs to?
Belongs to the CrgA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UGTP_BACAA
Sequence: MIKNPKVLILTAHYGNGHVQVAKTLEQTFRQKGIKDVIVCDLFGESHPVITDITKYLYLKSYTIGKELYRLFYYGVEKIYDKKIASWYANFGRKRLKLLLQAEKPDIVINTFPIIAVPELKKQTGISIPVYNVLTDFCVHKIWIHREVDRYFVATDHVKKVMVDIGVPAEQIVETGIPIRSSFELKINPDIIYNKYQLCKNKKILLIVAGAHGVLGSVKELCQSFMSVPDLQVVVVCGKNEALKQDLVGVQETNPDALKVFGYVENIDELFRVTSCMITKPGGITLSEAAALQVPVILYKPVPGQENENAMYFERKGAAVVIRDDSEVFAKTEALLQDDMKLLQMKEAMKSIYRPEPADHIVDTILAENHVEPNHIPIKSPALAQSFT
What is the function of this protein?
Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids.  Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol).  Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
What are the official names of this protein?
Processive diacylglycerol beta-glucosyltransferase, Beta-diglucosyldiacylglycerol synthase, Beta-DGS, DGlcDAG synthase, Glc2-DAG synthase, Beta-gentiobiosyldiacylglycerol synthase, Beta-monoglucosyldiacylglycerol synthase, Beta-MGS, MGlcDAG synthase, Beta-triglucosyldiacylglycerol synthase, TGlcDAG synthase, Diglucosyl diacylglycerol synthase (1,6-linking), Glucosyl-beta-1,6-glucosyldiacylglycerol synthase, UDP glucosyltransferase, UDP-glucose:1,2-diacylglycerol-3-beta-D-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. UgtP subfamily.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RIMO_NOVAD
Sequence: MGRAKMASQIPPREIPEAPKVGMVSLGCPKALVDSERILTRLRADGYAMSADYAGADVVLVNTCGFLDSAKEESLSAIGEAIAENGRVIVTGCMGNEAEAIRAKFPQVLAVTGAHQYEAVVEAVHEAAPPSMGPYIDLIPQADPGDVKLTPRHYSYLKISEGCNHACAFCIIPSLRGKLASRRIDAVLREAEKLVAAGTKELLVISQDTSAYGVDVRHEERMWKGRPVRTHMTDLARELGQLRTPQGETPWVRLHYVYPYPHVDAVIPLMAEGLVTPYLDIPFQHASPNVLRAMKRPANEAKVLERIKAWREICPDLAIRSSFVVGFPGETQADFEYLLEWLEEAQLDRVGGFRFEPVAGAAANDLPDQVPEEIKEERYARLMEKTEAISAARLSAKVGRHIKVIVDEVGEPDEDGDIGATARSQADAPEIDGAVYLRNVPASLKPGDFAEVLVEDADAHDLYGVIADRQG
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP1_COLGU
Sequence: MARYRCRRSQSRSRCCRQRRRCRRRRRQRFRARKRAMRCCHRRYRLRCRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SRA27_CAEEL
Sequence: MAMYTNQTAEELETWRCTSDGIFKSQNSIWMKINFVFVFILIFLTFYLSFKAARVLKNHNVYSKGSQILLMITLLNANLNQLIFLEIRIRHLVHIFINSEDPCKIEFHSPECTYDQTIYAFTSVMSTGLLSALTFDRFFALYASTVYVRNSKDSAYMLITVSIIVTVIVHIRTYGGVSRAGYVPSCTYPPQLSLNTYQVVNNAIFWIIMANCVLTIAVLLLNIYKDKRIKKSVFDTKTRYNSFENVLTTKAICSVTSTQFVFLSFSTAALAIIRTLEAGMSEEVFHINIQYINGGVYGNLSIPVLIYLKTNQCILQRRKSIDKMTNHTGTVDSHISSLKTAWET
What are the official names of this protein?
Serpentine receptor class alpha-27, Protein sra-27.
What is the protein family that this protein belongs to?
Belongs to the nematode receptor-like protein sra family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYR_AERPE
Sequence: MASSIDPLTRLHGILSSYLSEVLGVDRSVVERLLAPPPRKEYGDLGFPLMRFARSSNASADSIVESLRGKLWERGITWASPTLEAGYLNIVFDVEKLGDEVFRLLASGWRPSTARTSRPETIVVEHTSANPIHPLHLGHARNSSLGDALARLLEARGHRVNRRFYVDDVGRQAVVASLGFKLSGVTPRELASRMGVKVDHAVGWVYAVTHNALETVTARKRGDTSKVDEALSTLARLKERGDREVFDRILEAVGSLDDPEGLVSEMMRKYERGEEPEKSLIRGVVSAVLEGFRETLGRFGVDFDDWDWESDLLWSGLVNKIIEEARRSPFLTTHKDAIALDIPRIVREVLARDPEAASTIKLPRSLEIPPLILVRSDGTTLYTTRDLAYSVYKFRVTGADRVINVIGADQRLPQLQIRLALLGLGYRREALNMMHYDYEIVSLPGRRMSSRRGEYVTLDELLEMAKARSVREVESRNPGADRDWIESTAEKIAVGAVRFALVRPGRLKPITLDVERILDLKENTAPYLQYTYARASSILEKHGEIDYLKAHPASLEEGSRRELFVEALRFPLVSAKAADDLAPEDLASYLLRLADMFNSWYQKDSVIHEEWEGARHAKAALVLLVKSVIGEGLRLLGVEPLEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISZ_PSESM
Sequence: MATVDRWLLPDGIEEVLPPEAARIEVARRQVLDLFQSWGYEFVVTPHIEYLESLLTGAGSDLDLRTFKVIDPQSGRQMGFRADITPQVARIDAHTLKREGPSRLCYAGSVLHAQPRALSSSRSPIQLGAELYGDASPSSDVEVISLMLAMLQLADVPDVHMDLGHVGIYRGLARAAGLSGEVEQQLFDALQRKAIDEVVALTANLPPELASMLRALVDLCGGREVLDAARDRLAGAPAPVLEALDDLLAIADRLAARFPQLPLYFDLGELRGYHYHTGVVFAVFVPGVGQSIAQGGRYDDIGADFGRARPATGFSTDLKTLVTLGQAEIVLPSGGIWMPDSTDAALWQQVCQLRSEGQRVVQALPGQQVSAAREADCDRQLIQHGEHWQVMPLAS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_ROSCS
Sequence: MALSPEKEKALAAAMSQIDRKYGKGSIMRMGEASSKLAIEVIPTGSIALDIALGVGGVPRGRVVEIYGPESSGKTTLAQHIIAEAQKMGGVAAFIDAEHAFDPVYAKRCGVDVDNLLVSQPDYGEQALEICETLVRSNAVDVVVVDSVAALVPRAEIEGDMGDSLPGLQARLMSQALRKLSGAISKSRVVVIFLNQLRLKIGVMFGSPETTTGGQALKFYASVRMDIRRIETLKNGQETIGSRTRVKVVKNKVAPPFRQAEFDIMHNEGISRAGNILDVGVELDIIRKSGAWFYLGEDRLGQGRENAKQFLNENPALADEIERLIRAHAMAAPISIAASKADDVVDDAGLFEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADHQ_RABIT
Sequence: MSTKGKVIKCKAAIAWEAGKPLSIEEVEVAPPKAHEVRVQIIAASVCRSDTYVINPAFKEGLLPVILGHECAGIVESVGPGVNNFKPGDKVIPLYVPHCRKCKFCQSPLTNFCTKFSEHKNPIIEQELMDDKTSRFTCKGKSIYHFLGISAFSQYTVVKDINLAKIDDDANLKRVCLIGCGFSTGYGAAINDAKVTPGSTCAVFGLGGVGLSAVIGCKTAGASRIIAVDINSDKFAKAKALGATDCLNPRELNKPVQDVIVEMTNGGVDFAIDCAGGSEVMKATVDCTTVGWGSCTFVGVNVNDKGLTISPVELILGRTLRGSSFGGWDVDTVPKLVSDYKNGKFNLEALVTHTLPFEKINEALDLLKQGKSIRTILIY
What are the official names of this protein?
Alcohol dehydrogenase class-2 isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EZRI_RAT
Sequence: MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWYFGLQYVDNKGFPTWLKLDKKVSAQEVRKENPVQFKFRAKFYPEDVADELIQDITQKLFFLQVKEGILSDEIYCPPETAVLLGSYAVQAKFGDYNKEMHKSGYLSSERLIPQRVMDQHKLSRDQWEDRIQVWHAEHRGMLKDSAMLEYLKIAQDLEMYGINYFEIKNKKGTDLWLGVDALGLNIYEKDDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMLREKEELMLRLQDFEQKTKRAEKELSEQIEKALQLEEERRRAQEEAERLEADRMAALRAKEELERQAQDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRAKEAQDDLVKTKEELHLVMTAPPPPPPPVYEPVNYHVQEGLQDEGAEPMGYSAELSSEGILDDRNEEKRITEAEKNERVQRQLLTLSNELSQARDENKRTHNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEAM
What is the function of this protein?
Probably involved in connections of major cytoskeletal structures to the plasma membrane.  In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole.  Along with PLEKHG6, required for normal macropinocytosis (By similarity).
What are the official names of this protein?
Ezrin, Cytovillin, Villin-2, p81.
What are the subcellular locations of this protein?
Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell projection, microvillus. Note=Localization to the apical membrane of parietal cells depends on the interaction with PALS1. Microvillar peripheral membrane protein (cytoplasmic side) (By similarity). Localizes to cell extensions and peripheral processes of astrocytes. Colocalizes with EZR and SLC9A3R2 at the apical cell membrane of glomerular epithelium cells.
Protein: KHSE_METM7
Sequence: MKKVKVCSPGTSANLGPGYDIFGLALSKPYDTLEVEKTEQGITISVDGEKAEEISTKVDENTAGVVAKKMMEDFNIESGIHIHINKGIKPGSGLGSSSASCAGVAFALNELFELGLSKLELVKYSSLGEAVAAGAPHADNVAPAIFGGFTLTTSYDPLEVLHIPVDIEVLVALPNIQVSTKTAREILPKEIPINDMVNNVGKAAGMIYALYNNDLELFGRYMSKDCVVEPCRANLIDGYDEVKEKVKDMVYGITISGSGPAIITIPKKEHVIDIENIFKDVWNCPVYYTKVGPGCYVEEIE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_CLOD6
Sequence: MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKIKELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAGGSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIKGLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVNILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKYKQVYVVNSSQKGVEICGEFN
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ISPF_SALTO
Sequence: MVIVPRVAIGVDMHAFESGRPCWVAGLHWPGQDGLAGHSDADVAAHAACNALLSAAELGDLGANFGVGQPEWSGASGVALLSESARRVRTAGYTIGNVSVQVIGNRPKIGPRRAEAQQVLSAAVGAPVSVSAATTDGLGFPGRDEGLTGIAVALVYAAPAA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: TRHO_PARXL
Sequence: MSIVNLSSYQFATIEDTAAWRPFVTERCNALGLKGTVLLAPEGINLFVAGTRENTDAFIHYIRHDALFEGKFADLQFKESLSDKQPFTRMLVKLKREIITMKKPAIRPELGRAPFVDAPTLKSWLDRGHDDEGRPVVMLDTRNAFEVDVGTFDNALDYRITKFSEFPEVIEQNRADLEGKTIVSFCTGGIRCEKAAIHMKDVGIENVYQLEGGILKYFEEVGGAHYHGDCFVFDYRTALNPQLEPSKTTQCFGCRAVVTPEAQQSPLYVAGKTCPECHPDSKAARAA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RL3_STRP6
Sequence: MTKGILGKKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETDGYEAVQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAELSVEQFEAGDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRLAGRMGGNRVTVQNLEIVQVILEKNVILVKGNVPGAKKSLITIKSAVKAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ORYH_ASPOR
Sequence: MYLSLRLVSLALCIAPLASAGNNSTPLVQACTGYSFPRVACMYRYASKMPLDFYRKASVDISNVDTYSSTEVANDDSFQQVGKATFLVWDQQRGSEILGSDPAYDIVFTISTGGHEAPVYVPDTNELWFSELGKGELHQQVISLDGDSPTISEVLTDPPLYAPSGARYRNGKIYFSAGGGNSTLEGGPYHPGIYSVDPKTRKSTIEVNNYFGWYFNQVSMPTAHTRGGSPLSHFCTLVDPRLVAHGLTFQHRPTTWILTNTVASGLVILVSSWTRDLTLVHTDAAIVLARNHGTSTVAPQVQASVYRYDPETGAVNIVDDTLHCPNGVAFSPDYKTLYLTDTDAGVPMIDPRVPLSEVPSLQYNSTNRRTVYAFDVSEDGSYLKNRRPIYTAKDFVPDGLKVASNGYVITGAGKGVDILDTTGTPLLSIQTNFTAVNMVFGGKNLDELWIVGHGAVARARLNLTGPALE
What is the function of this protein?
Lactonohydrolase; part of the gene cluster that mediates the biosynthesis of oryzines, natural products with an unusual maleidride backbone (PubMed:30104550).  The two subunits of the fungal fatty acid synthase oryfasA and oryfasB probably form octenoic acid (Probable).  This fatty acid is most likely activated by the acyl-CoA ligase oryP to give octenyl-CoA before the citrate synthase-like protein oryE catalyzes condensation with oxaloacetate to form tricarboxylic acid (Probable).  The next steps of the pathways are conjectural, but a favorite possible route has been proposed, beginning with decarboxylation and concomitant dehydration by the decarboxylase oryM, followed by tautomerization, which may lead to the production of a diene intermediate (Probable).  Reduction of this diene intermediate could give the known metabolite piliformic acid (Probable).  On the pathway to oryzine B and oryzine A, however, hydroxylation of the diene by the alpha-ketoglutarate-dependent dioxygenase oryG and lactonisation by the lactonohydrolases oryH or oryL could give oryzine B directly (Probable).  Finally, enoyl reduction by the dehydrogenase oryD would then convert oryzine B into oryzine A (Probable).
What are the official names of this protein?
Lactonohydrolase oryH, Oryzines biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the SMP-30/CGR1 family.
Protein: GHT1_SCHPO
Sequence: MSKTLTITMLLFVSMAGWMFGADTGSIGGITNMRDFQSRFADRYNPVTDTYSYSSARQGLITGMVNVGSFFGCLISSPTTDRIGKRNSIIGFCVIYLIGVIIQVTAVPSWVQIMVAKIWTGLGIGALSVLAPGYQSEVAPPHIRGTIVVTYQLCVTAGIFIAACINMGTHKLYKTAQWRVSIGINLLWGIITLVGVSFLSESPRYLVSIGKDDEAIQVMCKNAELPPDSDIIQTEYKQIKSDCEAAVEGGPCTWPEIFGKEIRYRTFLGMAIMSFNQLTGCNYYFYYGTQVFKGTGMESPYLASLILDAVNFGCTFGGLFVLEYCGRRVPLIIGGVWQSICFFIYAAVGNRALTRKNGTSNHRAGAVMIVFSCLFIFSFAQTWGPAAYVIVGESYPIRYRSKCAAVATTSNWLWNFLISFFTPFITNSIGFKYGYIFASCNLCASIVTFLFAHESKGLTLEEINELYLSDAKPWMSRPKNLSEMAEAKEVEREETRPKGESARYLEHADSNSDSEDLSSSANNDVHEPVARQDPFNENEVEKSRTRPSQESYTTSSN
What is the function of this protein?
High-affinity glucose transporter.
What are the official names of this protein?
High-affinity glucose transporter ght1, Hexose transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RIMO_ROSDO
Sequence: MSTNPPDLRPDLAPKARLTQPDRPGQPTIGMVSLGCPKALVDSERILTRLRAEGYGISPDYDGADAVIVNTCGFLDSAKAESLSAIGEALNENGRVIVTGCLGAEPEYITGAHPKVLAVTGPQQYEQVLDAVHAAVPPSPDPFVDLLPATAVSLTPRHFSYLKISEGCNHKCKFCIIPDMRGRLASRPAHAVMREAEKLVDNGVRELLVISQDTSAFGVDIKHAEERGHRAHITDLARDLGSLGAWVRLHYVYPYPHVRQLIPLMADGLVLPYLDIPFQHAHPDVLRRMARPAAAAKTLDEIAAWRAICPDLTLRSTFIVGYPGETEEEFQTLLDWLDEAQLDRVGCFQYENVAGARSNALPDHVPEDVKQDRWNRFMAKSQDISEAKLAAKVAQRLEVIVDEVDADAATCRTKADAPEIDGNLFIDDGHDGLKPGDIVTVEVDEAGEYDLWGRLAPSA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y759_ARCFU
Sequence: MLYHLNNNGVSEVVGALLTVVVIVTAAGIIYVISHPVIANSIDNVNYQNAVKNMAEIKEIVQRMKYGSEVATSKVIQLNGGSMSNARFFNFTVFTTELPPGLQGNPNPNINAIIHAAHDIEVDWYTHTLNIEIAGREIVFESGIFVKEYGSVNPIPISEPDIIVTNDTLYLSIYDFIGDYSAGGQKITINFKHNFTTIFSNVTSFELKSEFCDIWKKSFEKALNDVPSKPADFEDDDCIDNTIKIKKASGDISIIFTRVEVT
What are the official names of this protein?
Uncharacterized protein AF_0759.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSBY_NOSP7
Sequence: MDIDYRIAIVLAPVVIAASWAVFNIGAAALRQIQGFLDREA
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.