PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_BURMA
Sequence: MIETDKLAAERIIAATPASSHEEAFERALRPRQLDEYVGQEKVRDQLEIFIEAAKRRSEALDHVLLFGPPGLGKTTLAHIIAREMGVNLRQTSGPVLERAGDLAALLTNLEANDVLFIDEIHRLSPVVEEILYPALEDYQIDIMIGEGPAARSVKLDLQPFTLVGATTRAGMLTNPLRDRFGIVARLEFYDAEQLSRIVRRSAALLNAQIDPAGALEIAKRSRGTPRIANRLLRRVRDYAEVKADGNITAAVADAALAMLDVDPVGFDLMDRKLLEAILHKFDGGPVGVDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRVATLLTYRHFGLSAPDAANPVRNLWDTPDAEC
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y462_YERPE
Sequence: MLIIISPAKTLDYQSPLATTKFSQPEMLDKSQALIEICRELTPAQISSLMGISDKLAGLNAARFSEWQPDFTPANARQAILAFKGDVYTGMQAESFSEADFDFAQQHLRMLSGLYGLLRPLDLMQPYRLEMGTKLANPRGKDLYAFWGDQITEKLNQALELQGDNILINLASDEYFKAVKPAKLSGSLIKPVFLDEKNGKYKIISFYAKKARGLMSRFIIQNKLTKPEQLVDFNLEGYEFDAGLSAKNELVFKRAEQH
What are the official names of this protein?
UPF0246 protein YPO0462/y3714/YP_3720.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: KDSA_RALPJ
Sequence: MKLCDFEVGLDKPFFLIAGTCVIESEQMAIDTAGTLKEITGALGIPFIYKSSFDKANRSSDASFRGLGMEEGLRILSEVRRQVGVPVLTDIHEIDEIKPVAEVVDVLQTPAFLCRQTDFIRACAQSGKPVNIKKGQFLAPHDMKNVIDKARHAARDAGLPEDNFMACERGASFGYNNLVSDMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLARAAIAVGVAGVFMETHPDPACAKSDGPNAVPLRRMKDLLSVLKELDALTKRSGFLENQFD
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_LIMF3
Sequence: MPNRKIPRATAKRLPVYYRYLNVLLNANKHRVSSTELSEAVQVDSATIRRDFSYFGELGKRGYGYDVEKLLNFFKGILKQDKLTSVALVGVGSLGSALMNYNFHQSTNLRISAAFDPKESLANTVKSGIPVYPVEDMKKQIKEQQIDAVILTVPGSESQAVTDQLVEAGVHGILNFTPVRLSVPKDVQVQNIDLTNELQTLIYFIESNKVTTDDED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPC3_YEAST
Sequence: MDELLGEALSAENQTGESTVESEKLVTPEDVMTISSLEQRTLNPDLFLYKELVKAHLGERAASVIGMLVALGRLSVRELVEKIDGMDVDSVKTTLVSLTQLRCVKYLQETAISGKKTTYYYYNEEGIHILLYSGLIIDEIITQMRVNDEEEHKQLVAEIVQNVISLGSLTVEDYLSSVTSDSMKYTISSLFVQLCEMGYLIQISKLHYTPIEDLWQFLYEKHYKNIPRNSPLSDLKKRSQAKMNAKTDFAKIINKPNELSQILTVDPKTSLRIVKPTVSLTINLDRFMKGRRSKQLINLAKTRVGSVTAQVYKIALRLTEQKSPKIRDPLTQTGLLQDLEEAKSFQDEAELVEEKTPGLTFNAIDLARHLPAELDLRGSLLSRKPSDNKKRSGSNAAASLPSKKLKTEDGFVIPALPAAVSKSLQESGDTQEEDEEEEDLDADTEDPHSASLINSHLKILASSNFPFLNETKPGVYYVPYSKLMPVLKSSVYEYVIASTLGPSAMRLSRCIRDNKLVSEKIINSTALMKEKDIRSTLASLIRYNSVEIQEVPRTADRSASRAVFLFRCKETHSYNFMRQNLEWNMANLLFKKEKLKQENSTLLKKANRDDVKGRENELLLPSELNQLKMVNERELNVFARLSRLLSLWEVFQMA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC3, RNA polymerase III subunit C3, C82, DNA-directed III 74 kDa polypeptide, C74.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RH9_ORYSJ
Sequence: MYSILRRAAPLRRRAVSALAAAVLRREEAAAEVVVSRRATIPAAWFHSSPAWLGFRETGAAGAAARPQYAADEGLFYEEDKRGAKAGGVAAGGAEEGLEVAKLGISPKIVSQLASRGITKLFPIQRAVLEPAMQGKDMVGRAKTGTGKTLAFGIPILDAIIRHNEKNSPGKFPLAIVLAPTRELAKQVEREFSDSSNVETICVYGGTPISQQIRQLNYGVDVVIGTPGRVIDLLKRGALNLSEVRFVVLDEADQMLSVGFDEDVETILDRVPPKRQTLMFSATMPTWIQRLTQKYLKNPVTIDLVGEDDQKLAEGISLYSIASEGHAKPAVLGELIKEHAKGGKCIVFTQTKRDADRLSYTMGRSFQCQALHGDITQAQRERTLKGFREGHFNILIATDVAARGLDIPNVDLVIHFELPNSSELFVHRSGRTGRAGKKGKAIVMHSYQQSRAIRMVENDVGCKFTELPKINVEGSDLMSGGFDSFGGGGFGREGGGSYGRRGSFGSSSSRGGGFGDSGFGRSGGGFGRSGGGGFGRSSGGGFGDSGFGRSGGGGFGDSGFGRSGGGGYGDSGFGSSGGGSGRSGFGRSGGFGDSGSGRFGGGFGNSGSGSFGNFGGNNSGQSGGFGSS
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
Protein: YCDX_SALPB
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAEAKRKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRLVDGVGILRGIEANIKNINGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKETNTQAMIATIASGKVHIISHPGNPKYPVEVKAIAQAAAKHHVALEINNSSFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTLGDFTECRKILDAVNFPEDRILNVSPQRLLAFLESRGMAPVPEFAEL
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: TDXH_PYRFU
Sequence: MIVIGEKFPEVEVKTTHGVIKLPDHFTKQGKWFMLFSHPADFTPVCTTEFYGLQIRLEKFRELGVEPIGLSVDQVFSHLKWMEWIKEKLGVEIEFPVIADDRGDLAEKLGMIPSGSTITARAVFIVDDKGIIRAIVYYPAEVGRDWDEILRLVKALKISTEKGVALPHKWPNNELIGDKVIVPPASSVEQIKEREEAKAKGEIECYDWWFCYKKLE
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP54_DANRE
Sequence: MVLADLGRKITSALRSLSNATIINEEVLNAMLKEVCAALLEADVNIKLVKQLRENVKAAIDLEEMASGLNKRRMIQHAVFKELVKLVDPGVKAWTPTKGKNNVIMFVGLQGSGKTTTCSKLAYYFQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIAAEGVEKFKSENFEIIIVDTSGRHKQEDSLFEEMLQVSNAVQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEELIDKLKHGQFTLRDMYEQFQNIMKMGPFGQIMGMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDNKDGAKLFSKQPNRIQRVARGSGVATRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVNPSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).  As part of the SRP complex, associates with the SRP receptor (SR) component srpra to target secretory proteins to the endoplasmic reticulum membrane.  Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.  Displays basal GTPase activity, and stimulates reciprocal GTPase activation of the SR subunit SRPRA.  Forms a guanosine 5'-triphosphate (GTP)-dependent complex with the SR subunit srpra.  SR compaction and GTPase mediated rearrangement of SR drive SRP-mediated cotranslational protein translocation into the ER (By similarity).  Requires the presence of srp9/srp14 and/or srp19 to stably interact with RNA (By similarity).  Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
What are the official names of this protein?
Signal recognition particle subunit SRP54, Signal recognition particle 54 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm.
Protein: AROD_LACLS
Sequence: MRRTKIVVPIMLTELTELEKVSVSDYLSADIVEWRADFLSADDIFEMAPKFFEKFKESKILFTLRTVREGGNIQVSEKKYLQILQEILKFEPDYIDVEYFSHGPSFAALKNYREKIVLSYHNFDEVPTDLTSRLIKMHEEGTAFVKVAVMPERECDVLDLLQITRDMTLEYGNHFISMAMGDLGRLSRISGYLTGSCWTFAGLENSSAPGQISLKETVEILDLLENELA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: TAL_CUPTR
Sequence: MNQLEQLRQFTTVVADTGDFQLMKQYTPQDATTNPSLILKAVQKPEYRHLLERAVQDHHGNGGVDAVMDEVLIAFGCEILAIVPGRVSTEVDARLSFDTTATVNKARHLIQLYEQRGIARERVLIKIASTWEGIRAAEILQRDGIRCNMTLLFSLVQAVACAEAGAQLISPFVGRIFDWYKKQAGEQWDAAANGGDNDPGVRSVRQIYDYYKKFGYPTEVMGASFRSTAQILSLAGCDLLTISPELLEQLAGGQGPVVHKLSVDQAQAANIARITADEPSFRWQLNEDAMATEKLAEGIRLFAADAVKLEKLIGEIAK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_TRIV2
Sequence: MPYRMSRQAYAETYGPTVGDRIRLADTELFIQVEQDFTTYGDEVKFGGGKVIRDGMGQSPIANADGAVDLVITNALILDWWGIVKADIGIKDGKIFKIGKAGNPYIQDHVDIIIGPGTEALAGEGMILTAGGIDTHIHFICPQQIEVAIASGITTMIGGGTGPATGTNATTCTPGPWNMYRMLQAADAFPMNLGFLGKGNASQPQGLTEQIFAGAIGLKLHEDWGTTPATIDTCLSVADEYDVQVAIHTDTLNEAGFVEDTIAAFKNRAIHTYHTEGAGGGHAPDIIKVCGQANVLPSSTNPTRPYTVNTLDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMIASDSQAMGRVGEVIIRTWQTSHKMKVQRGSLAGDGKADNLRAKRYVAKYTINPAITHGISQYVGSVEAGKLADLCLWRPGFFGVKPEIVIKGGMIAWSQMGDANASIPTPQPVHMRPMFGSFAGARNATSLTFVSQAALERDIPQQLGLRKSAVAVSGTRQLTKQEMKLNDALPHIEVDPETYEVRADGELLTCEPATVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VGH_BPS13
Sequence: MFGAIAGGIASALAGGVMSKLFGGGQKAASGGIQGDVLATDNNTVGMGDAGIKSAIQGSNVPNSDEAAPSFLSGAMAKAGKGLLEGTLQAGTSAVSDKLLDLVGLGGKSAADKGKDTRDYLAAAFPELNAWERAGAGASSSAIVDAGFENQKELTKMQLDNQKEIAEMQNETQKEIAGIQSATSRQNTKDQVYAQNEMLAYQQKESTARVASIMENTNLSKQQQVSEIMRQMLTQAQTAGQYFTNDQIKEMTRKVSAEVDLVHQQTQNQRYGSSHIGATAKDISNVVTDAASGVVDIFHGIDKAVADTWNNFWKDGKADGIGSNLSRK
What is the function of this protein?
Minor spike component of the viral shell.  Involved in the ejection of the phage DNA in the host and is injected with the DNA in the periplasmic space of the host.  Involved in the determination of the phage host-range (By similarity).
What are the official names of this protein?
Minor spike protein, H protein, Pilot protein.
What are the subcellular locations of this protein?
Virion.
Protein: GUAA_PSEPK
Sequence: MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFNPRGIILAGGPESVHEANSPRAPQAVFDLNVPVLGICYGMQTMAEQMGGKVEGSDLREFGYARVDVVGKSRLLDGIEDHVDDDGVLGLDVWMSHGDKVTQMPGNFNILASTPSCPIAGMYDDVRGYYGVQFHPEVTHTKQGGRILSRFVQDICGCEALWTASNIVEDAIAQVRAQVGSANVLLGLSGGVDSSVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMAMFKENMGVKVIRADAEKQFLDNLEGEADPEKKRKIIGRTFIDVFDAEASKLENIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDFMTARWAHLPYELLETVSGRIINEIDGISRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ARL1_MOUSE
Sequence: MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSEMANALGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ
What is the function of this protein?
GTP-binding protein.  Can activate phospholipase D with very low efficiency.  Important for normal function of the Golgi apparatus (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Membrane; Lipid-anchor.
Protein: GLYA2_BURPS
Sequence: MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRYYGGCEFADEVEALAIERVKRLFNAGHANVQPHSGAQANGAVMLALAKPGDTVLGMSLDAGGHLTHGAKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRGPRGGFVLTNDEEIAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFEALRTNPEGDHATEQRVRREIFALCERFPIY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, SHMT 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M2OM_CAEEL
Sequence: MSNEGGVPNVVKFAFGGTAGMGATLVVQPLDLVKNRMQLSGTTGKKEYRSSMHALTSIMKNEGVFAVYNGLSAGLLRQATYTTTRLGTYAFLLERFTEKDKPLSFGMKAVLGMTAGGIGSFVGTPAEIALIRMTGDGRLPVEQRRNYTGVVNALTRITKEEGVLTLWRGCTPTVLRAMVVNAAQLATYSQAKQALLASGKVQDGIFCHFLASMISGLATTIASMPVDIAKTRIQSMKVIDGKPEYKNAFDVWGKVIKNEGIFALWKGFTPYYMRLGPHTVLTFIILEQMNAAYFQYVLKRDVTSAL
What is the function of this protein?
Catalyzes the transport of 2-oxoglutarate (alpha-oxoglutarate) across the inner mitochondrial membrane in an electroneutral exchange for malate.  Can also exchange 2-oxoglutarate for other dicarboxylic acids such as malonate, succinate, maleate and oxaloacetate, although with lower affinity.  Contributes to several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism (By similarity).  Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (PubMed:21448454).  Regulator of apoptosis, insulin secretion and germline proliferation (PubMed:21448454).  Furthermore, plays a role in the oxidative stress response regulating endogenous levels of reactive oxygen species (ROS) (PubMed:21884719).  Involved in the regulation of lin-35/Rb-mediated apoptosis in the germline (PubMed:21448454).
What are the official names of this protein?
Mitochondrial 2-oxoglutarate/malate carrier protein, alpha-oxoglutarate carrier, Mitochondrial solute carrier 1, MISC-1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL36_SYNJB
Sequence: MKVRPSVRRICEKCRVIRRHGRVMVICSSNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RRP3_ASPCL
Sequence: MSAVKKRKIANKAPQYESDAESSSSHESVASKHSDNAEAQDGPESSETKPAPKSFKDLGIIDQLCEACATMGYKAPTPIQAESIPLALQDRDLIGLAETGSGKTAAFALPILQALMDKPQSFFGLVLAPTRELAFQISQSFEALGSTINVRCAVIVGGMDMVSQSIALGKKPHIIVATPGRLLDHLENTKGFSLRTLKYLVMDEADRLLDMDFGPLLDKILKILPRERRTFLFSATMSSKVESLQRASLSNPLRVSVSSNKYQTVSTLLQSYRFIPHKHKDIYLVYLLNEFVGQSAIIFTRTVHETQRISFLLRALGFGAIPLHGQLSQSSRLGALGKFRSRSRDILVATDVAARGLDIPSVDVVLNFDLPTDSKTYVHRVGRTARAGKSGVAISFVTQYDVEIWLRIEGALGKKLDEYDLEKDEVMVLAERVGEAQRQAIMEMKNFDEKKGTRAKKFGKGKRSRDEMDQEEG
What is the function of this protein?
ATP-dependent rRNA helicase required for pre-ribosomal RNA processing.  Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent rRNA helicase rrp3.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: METK_ANAD2
Sequence: MPLQDFLFTSESVTEGHPDKMADQISDAVLDAVLRQDPKGRVACETLLKTGYVMIAGEITTKARIDYPKLARETVRRIGYTSGDMGFDANTCAVLVAVDQQSPDIGQGVDTGGAGDQGMMFGYACDETPELMPAPIQYAHAVTKQLAKARRAGLDFLRPDGKSQVSVEYRDGRPVRIDTVVVSTQHAESVSNKRLHEAVREQVIAKALPKRLLDRKTRILINPTGRFVIGGPMGDTGVTGRKIIVDTYGGMGRHGGGAFSGKDPSKVDRSAAYMGRYIAKNVVAAGLASRCEVQVAYAIGVAEPVSVMVDTFGTAKVPEGKIARAVREVFGLTPRAIIEGLDLLRPVYEKTAAYGHFGRTEKTFTWERTDKKDALADAAGLSKIRAVASV
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_THET8
Sequence: MVLVLDFGSQYTRLIARRLRELRAFSLILPGDAPLEEVLKHRPQALILSGGPRSVFDPDAPRPDPRLFSSGLPLLGICYGMQLLAQELGGRVERAGRAEYGKALLTRHEGPLFRGLEGEVQVWMSHQDAVTAPPPGWRVVAETEENPVAAIASPDGRAYGVQFHPEVAHTPKGMQILENFLELAGVKRDWTPEHVLEELLREVRERAGKDRVLLAVSGGVDSSTLALLLAKAGVDHLAVFVDHGLLRLGEREEVEGALRALGVNLLVVDAKERFLKALKGVEDPEEKRKIIGREFVAAFSQVARERGPFRFLAQGTLYPDVIESAGGHGAAKIKSHHNVGGLPEDLEFELLEPFRLLFKDEVRELALLLGLPDTLRLRHPFPGPGLAVRVLGEVTEERLEILRRADDIFTSLLREWGLYEKVAQALAVLTPVRSVGVAGDERKYGYVLALRAVTTEDFMTADWARLPLEFLDEAARRITRRVPEIGRVVYDLTSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL16_MESH7
Sequence: MLQPKKTKHRKTFRLYHDKRDAHSGNFVAFGDYGLQATGSAWVSAAQIEAARIAITRRMGREGQVIIRVFPHLALTSKPIGVRMGSGKGSVDRWVAVVKRNTILFEVRGVKDEIARDALRLGGHKLPLKWKIVATV
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y1852_CHLAA
Sequence: MPAENSFDIVSDFDQQELVNAVDQTLREVQTRYDLKDAGVTITLTKTELIIEADSEMSLRSVRDVLETKALRRKLSLKIFDYGKPTDASGGRVRQVVTLRRGIDSELAKKLSKMIRDRFPKVQPRIQGDSLRVAGKSRDELQAVIAFLREREGEIPVPLQMTNYR
What are the official names of this protein?
UPF0234 protein Caur_1852.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: PYRF_PYRFU
Sequence: MIVLALDVYEREKALSIAEDVKDYISMIKVNWPLIIGSGLGVISELKKKTGLPIIADLKLADIPNTNRLIAKKVYDAGADYIILHSFVGRDSVKAVKELGEIIMIVEMSHPGALEFINPLTDKFIDMANEIKPFGVIAPGTRPERIRYIRERLSKDIKVLTPGIGAQGGSPVEALKAGADYIIIGRAIYNAERPREAAKKIFEEVKEWSSR
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NHAB_YERPY
Sequence: MDITNRQAVLKNFLGNSPDWYKLAIMGFLIINPLVFFFVSPFVAGWMLVIEFIFTLAMALKCYPLQPGGLLAIQAVAIGMTSPHQVAEEIANNLEVLLLLVFMVAGIYFMKQLLLFVFTKLLLNIRSKTILSLAFCLASAFLSAFLDALTVIAVVISVSVGFYTIYHNVTSNHSDKDITDDSGIDNQDSHETLEQFRAFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKSAGWNFADFFIRMLPVTLPVFICGLLVCLLVEKFKLFGYGAQLPERVRQVLTEYDQQASAKRTKQEKMKLIVQAIIGVWLVLALALHLAEVGLVGLSVIILATSFCGITNEHSLGKAFQEALPFTALLTVFFAVVAVIIEQSLFTPIIQFVLQASPSAQLSLFYLFNGLLSSVSDNVFVGTVYINEARSAFEHGIVSLQQFELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVYMALPYTLVMTIVGLLGVEFLLVPMTEWLTQAGWISLPHITNGVAIPH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCY_SULIK
Sequence: MIIIISGPPGSGKTSVAIKLANELSYKFISAGKIFRDIAQKMGLDIINLNKVAESNFDIDKMVDKKIFEFILSEKNLIIESHIAGWLFREYTNIAIYLWAPLKIRANRIAIRDKISYDQAISQIIKREYMHYKRFNKFYGIDINDLSVFDLVINTSNVDVNNIVKLILTYLSSVSQNPQPLKEKDINDK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_ACIBT
Sequence: MSMQDTVADMLTRVRNAQMAKKQTVSMPSSKLKVAIANVLQQEGYISNVEVAQEETKSTLTITLKYFEGKPVIEMVKRVSRPGLRQYRGKDKLPSVKQGLGIAIVSTSKGIMTDRAARAAGIGGEVIAFVS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SNAB_MOUSE
Sequence: MDNAGKEREAVQLMAEAEKRVKASHSFLRGLFGGNTRIEEACEMYTRAANMFKMAKNWSAAGNAFCQAAKLHMQLQSKHDSATSFVDAGNAYKKADPQEAINCLNAAIDIYTDMGRFTIAAKHHITIAEIYETELVDIEKAIAHYEQSADYYKGEESNSSANKCLLKVAAYAAQLEQYQKAIEIYEQVGANTMDNPLLKYSAKDYFFKAALCHFIVDELNAKLALEKYEEMFPAFTDSRECKLLKKLLEAHEEQNSEAYTEAVKEFDSISRLDQWLTTMLLRIKKSIQGDGEGDGDLK
What is the function of this protein?
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
What are the official names of this protein?
Beta-soluble NSF attachment protein, SNAP-beta, Brain protein I47, N-ethylmaleimide-sensitive factor attachment protein beta.
What is the protein family that this protein belongs to?
Belongs to the SNAP family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.