PharMolix/UniProtQA huggingface dataset:
Protein: ORF1_LRVLG
Sequence: MPMSLDSLAVGMVALLVDYYSKALRASLNSTGIDRRWGDQWPSTVELTGRGVIEWESPTFCICSSSRSTAIV
What are the official names of this protein?
Putative ORF1 protein.
Protein: SPLB_STAAS
Sequence: MNKNVVIKSLAALTILTSVTGIGITLVEEVQQTAKAENNVTKVKDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
What is the function of this protein?
Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln.
What are the official names of this protein?
Serine protease SplB.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: EX7L_YERPS
Sequence: MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPSPAKQVGVITSASGAALHDVLHVLQRRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHETDVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLLKLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTH1_HAEPH
Sequence: MIEIKDKQLTGLRFIDLFAGLGGFRLALESCGAECVYSNEWDKYAQEVYEMNFGEKPEGDITQVNEKTIPDHDILCAGFPCQAFSISGKQKGFEDSRGTLFFDIARIVREKKPKVVFMENVKNFASHDNGNTLEVVKNTMNELDYSFHAKVLNALDYGIPQKRERIYMICFRNDLNIQNFQFPKPFELNTFVKDLLLPDSEVEHLVIDRKDLVMTNQEIEQTTPKTVRLGIVGKGGQGERIYSTRGIAITLSAYGGGIFAKTGGYLVNGKTRKLHPRECARVMGYPDSYKVHPSTSQAYKQFGNSVVINVLQYIAYNIGSSLNFKPY
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-GCGC-3', methylates C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.HhaI, M.HhaI, Cytosine-specific methyltransferase HhaI, Modification methylase HhaI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: BCP1_ARATH
Sequence: MGRQNIVVVVALVFMAIIGLAAAASSPSPSASPSKAPAASKTDHVEAPVTDDQIGTTDDDAAPTPGDGDVAVAGPLGSDSSYDNAPTGSADSAKSGAAALGVSAVVVGVTSIAGSFLLL
What is the function of this protein?
Major pollen protein required for pollen fertility and development.  Active in both diploid tapetum and haploid microspores.
What are the official names of this protein?
Anther-specific protein BCP1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL9_GLUOX
Sequence: MSQTALILLQRVEHLGQMGDLVHVKPGYARNFLLPQAKAMRATAANKKRFETERAQLEAQNLKKREEAERLAERMHELSVVIIRQAGDSGSLYGSVSTRDIAAAATEAGLTISRQQVVLAHPIKQLGLTEARIVLHPEVSIPLTVNVARSAEEAERQARGEAIGVQDEDENILGELQAENAAEEAAAEAAEASEEA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: SERC_SALSV
Sequence: MAQVFNFSSGPAMLPAEVLKLAQQELRDWHGLGTSVMEISHRGKEFIQVAEEAEQDFRDLLNIPSNYKVLFCHGGGRGQFAGVPLNLLGDKTTADYVDAGYWAASAIKEAKKYCAPQIIDAKITVDGKRAVKPMREWQLSDNAAYLHYCPNETIDGIAIDETPDFGPEVVVTADFSSTILSAPLDVSRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHESCPSILDYTVLNDNDSMFNTPPTFAWYLSGLVFKWLKAQGGVAAMHKINQQKAELLYGVIDNSDFYRNDVAQANRSRMNVPFQLADNALDKVFLEESFAAGLHALKGHRVVGGMRASIYNAMPIEGVKALTDFMIDFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIKE1_XENLA
Sequence: MTCTIDKILQDAKTLLERLKDHDNAAESLIDQSSVLHKRVKAMKEVGTAMPEKYQEELAEIKDASKLRPHVLLCQENTQIRDLQLENKELWLSLEEHQYALELIMSKYRKQMLQLIANKIPAPTEPVLEAHKTFSSDLECQIDRICVIGDAMRKAIQLDEDQAYNIQERLAQLELENKELREILSVRNESLRSSKKESEWNFSEK
What is the function of this protein?
Suppressor of IKK-epsilon.
What are the official names of this protein?
Suppressor of IKBKE 1, Suppressor of IKK-epsilon.
What is the protein family that this protein belongs to?
Belongs to the SIKE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_AZOVD
Sequence: MRFDPPLEEGHLLRRYKRFFADIETPDGEALCIHCPNTGSMFNCMAEGGRVWFSRSNDPRRKLPGTWELSETPQGRLACVNTARANPLVEEALRAGSIAELTGFTGLRREVRYGLENSRVDFCLDYPDGTAFVEVKSVTLGFADSPVAAFPDARTERGAKHLRELAVLARQGVRTVQLYCVNLSGIAAVRPAAEIDPGYAQALREAVAAGVEVLAYGAELSPAAIRLVRRLEVCL
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: MATK_CARPA
Sequence: MEEFQVYLELDRFRQHDFLYPLIFREYIYALAHDHSLNINNRSGLLENVSSANKYKYSSVIVKRFIFRMYQQNHLIISANDSNQKQFFGHNNNLYYEMISAVFAVIAEIPFSLRLVSSLKGKGPAKSHNLQSIHSIFPFLEDTFSHLNYVLDVLIPYPIHLETLVQTLRYWIKDTSSLHLLRFCLYEYCNWNWKSLITQKKSILNPRLFLFLYNSHVCEYESIFFFLRNQSSHLRSTSFGVLLERILFYGKIEHLIKVFVNDFQDILWLVKDPFMHYIRYQGKSILASKDTPLLMNKWKYYFVSLWQCHFYVWSQSRRVRIKQLSKDYLDFLGYFSSLRFNPLVVRSQMLENSFLIDNAIKKFDTKIPIIPMIGSLAKARFCNALGHPISKPAWADSADSDIIDRFVRICRNLSHYYSGSSKKKNLYRIKYILRLSCVKTLARKHKSTVRTFLKRVGSGFLEEFFTEEEEVLSLIFPRAYSASRKLYRGHIWYLDIICINDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TKSIA_AEDAE
Sequence: MNMFITVQIVIVLVLAVLSEAASLPTATERKDAMDEGPNQSDEPEGSVADPSTKDDDYSDSLKQDEKYYKVRLLNTGDKFYGLMG
What is the function of this protein?
Vasodilatory peptide.  May activate macrophages at the site of feeding.
What are the official names of this protein?
Prosialokinin.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_HALLT
Sequence: MGRRIQGQRRGRGGPTFRAPSHRYKAELSHKKLEDVDTITGEIVGIEHDPARSAPLAEIEFEDDDRRLVLAPEGVRVGDTIQVGVSAEIKPGNTLPLAEIPEGVPVCNVESNRGDGGKFARASGVSATLLTHDRDVAVVQLPSGEVKRLDPQCRATIGVVAGGGRTEKPFVKAGNKYHKMKARGTKYPRVRGVAMNAVDHPFGGGGRQHPGQPKSVSRDAPPGRKVGDIASKRTGRGSNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: VWA2_XENLA
Sequence: MRLPWVNGILAFLSSQVLQCLCVQELHVNAETANKISAAGRRMRCSSPLDILILLDGSNSIGRGSFERSKHFASKLCDALDIGSDLIRVGAMQYSGAPQVEFRLDSSFSKAAIKEKIKSIVFKGGPTETGLALKYIVWKGFPGGRPASVPKILIIVSDGKSQGNIKLPAAQIKGEDIEVFTVGVKFPRWEELHALSSEPQEAHVLFAEHVDDAVNGLATSLTNSSLCSSVPHGCSVQSFPCTRKTLETVKELTGNYMCWKGSARPGTVFPGHCPFYSWRRFYNKHQAQCHRTVCPDPCDSQPCKNGGTCIAEGQDKYHCVCPAGFGGDTECAPQLSLECNIDLLFLVDSSDTTSLEAFMQHKSFLKRFIQASLSDESPLNVGVAQYSNEVQMVVKIGEYQSMAELLKHIDNMRFMGGGLFTGKALRYVTQYGFKSTPVFSDVRDDLPRLVVLLTGSKSQDSVTGPATYARDQEVFLIGVTSDSNKGEMAEIVGNPLNLVTYSNPQQLFNQLPQLQKRICSIDVQGCQAQPLDLAFVLDASTAVGQEKFNRLKNFVTMVSLQFDINRDVTQIGLVTYSSRPETVFGLDTHDSGSSLLQGIGRASYMGGSASTGSALLRVYNDVMTVQKGARPGVNKAVVVITDGRGAEDAAVPAQKLRDNGIMVYVIGIGNIQRNSLLRLAGSEKFLISVPSYESLGHYEDSVVQRVCEDAKSPVNLCKPNPCMNDGVCILRQGSYRCDCRGWDGPHCETRILRGDSHWPQGLHSRSRQQRHSRKRRLKSVSGSRSSRKKP
What are the official names of this protein?
von Willebrand factor A domain-containing protein 2, A domain-containing protein similar to matrilin and collagen, AMACO.
What are the subcellular locations of this protein?
Secreted.
Protein: NAT11_ARATH
Sequence: MDSGSGFDPDTGNNKGNGSGGGNGYGERKFGAFFKRVEPFLPKKDLNPRDLRSWAKKTGFVSDYSGETSTSTRTKFGESSDFDLPKGRDQVVTGSSHKTEIDPILGRNRPEIEHVTGSEPVSREEEERRLNRNEATPETENEGGKINKDLENGFYYPGGGGESSEDGQWPKPILMKFGLRDNPGFVPLIYYGLQHYLSLVGSLVFIPLVIVPAMDGSDKDTASVISTMLLLTGVTTILHCYFGTRLPLVQGSSFVYLAPVLVVINSEEFRNLTEHKFRDTMRELQGAIIVGSLFQCILGFSGLMSLLLRFINPVVVAPTVAAVGLAFFSYGFPQAGTCVEISVPLILLLLIFTLYLRGVSLFGHRLFRIYAVPLSALLIWTYAFFLTVGGAYDYRGCNADIPSSNILIDECKKHVYTMKHCRTDASNAWRTASWVRIPYPFQWGFPNFHMRTSIIMIFVSLVASVDSVGTYHSASMIVNAKRPTRGIVSRGIALEGFCSLLAGIWGSGTGSTTLTENIHTINITKVASRRALVIGAMFLIVLSFLGKLGAILASIPQALAASVLCFIWALTVSLGLSNLRYTQTASFRNITIVGVSLFLGLSIPAYFQQYQPLSSLILPSYYIPFGAASSGPFQTGIEQLDFAMNAVLSLNMVVTFLLAFILDNTVPGSKEERGVYVWTRAEDMQMDPEMRADYSLPRKFAQIFGCRCC
What are the official names of this protein?
Nucleobase-ascorbate transporter 11, AtNAT11.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BGLA_THENE
Sequence: MKKFPEGFLWGVATASYQIEGSPLADGAGMSIWHTFSHTPGNVKNGDTGDVACDHYNRWKEDIEIIEKIGAKAYRFSISWPRILPEGTGKVNQKGLDFYNRIIDTLLEKNITPFITIYHWDLPFSLQLKGGWANRDIADWFAEYSRVLFENFGDRVKHWITLNEPWVVAIVGHLYGVHAPGMKDIYVAFHTVHNLLRAHAKSVKVFRETVKDGKIGIVFNNGYFEPASEREEDIRAARFMHQFNNYPLFLNPIYRGEYPDLVLEFAREYLPRNYEDDMEEIKQEIDFVGLNYYSGHMVKYDPNSPARVSFVERNLPKTAMGWEIVPEGIYWILKGVKEEYNPQEVYITENGAAFDDVVSEGGKVHDQNRIDYLRAHIEQVWRAIQDGVPLKGYFVWSLLDNFEWAEGYSKRFGIVYVDYNTQKRI
What is the function of this protein?
Broad substrate specificity glycosidase.  Releases glucose from soluble glucooligomers, with a preference for longer oligomers; acts more readily on cellotetraose than on cellobiose.  Displays similar activities towards the disaccharides lactose and cellobiose.  Is also able to hydrolyze various aryl-beta-glycosides in vitro.
What are the official names of this protein?
1,4-beta-D-glucan glucohydrolase, Glucan glucohydrolase, Beta-D-glucoside glucohydrolase, Beta-glucosidase, Glucan 1,4-beta-glucosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: DCHS_SOLLC
Sequence: MESDIKNETSFQELDMILTQYLETLSERKKYHIGYPINMCYEHHATLAPLLQFHLNNCGDPFTQHPTDFHSKDFEVAVLDWFAQLWEIEKDEYWGYITSGGTEGNLHGFWLGRRELLPNGYLYASKDSHYSIFKAARMYRMELQTINTLVNGEIDYEDLQSKLLVNKNKPAIININIGTTFKGAIDDLDFVIQTLENCGYSNDNYYIHCDRALCGLILPFIKHAKKITFKKPIGSISISGHKFLGCPMSCGVQITRRSYVSTLSKIEYINSADATISGSRNGFTPIFLWYCLSKKGHARLQQDSITCIENARYLKDRLLEAGISVMLNDFSITVVFERPCDHKFIRRWNLCCLRGMAHVVIMPGITRETIDSFFKDLMQERNYKWYQDVKALPPCLADDLALNCMCSNKKMHN
What are the official names of this protein?
Histidine decarboxylase, HDC, TOM92.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: TDCC_ECO27
Sequence: MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLMVKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGHYLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
What is the function of this protein?
Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system).
What are the official names of this protein?
Threonine/serine transporter TdcC, H(+)/threonine-serine symporter.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HBA_LEPPA
Sequence: MRFSQDDEVLIKEAWGLLHQIPNAGGEALARMFSCYPGTKSYFPHFGHDFSANNEKVKHHGKKVVDAIGQGVQHLHDLSSCLHTLSEKHARELMVDPCNFQYLIEAIMTTIAAHYGEKFTPEINCAAEKCLGQIVHVLISLYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: MUTS_SHEB5
Sequence: MNVIDTDDLEKHTPMMRQYLTMKAEHHDMLLFYRMGDFYELFYDDAKRASELLGISLTARGKSGGDPIPMAGLPYHAVEGYLAKLVQIGQSVAICEQIGDPATSKGPVERKVVRIVTPGTLTDEALLQERQDNLLAAVYQGKIGFGYATLDVSSGRFVIAELDTRESLEAELQRTNPVEILYSEDFGELGLLNGFKGKRRRPEWEFDYDTSIKLLLAQFGTKDLHGFGIADARLSLQAAGCLMQYVKDTQRTALPHINAITRFNQTDSIVLDAATRRNLELTQNLAGGRDNTLAAVLDNTATPMGSRILQRWIHQPLRDPKHIQARQQAVTELLDTAAHEGLHEQLKALGDIERIMARLALRTARPRDFARLRQALGLLPELQKSLSTLSAPHTTQLRQHLGEFPAEQALLERAIVDNPPMLIRDGGVIREGYNSELDEWRGLSEGASDYLVQLEAREKERTGINTLKVGYNRVHGYYIEVSRLQSSQVPLNYQRRQTLKNMERYITPELKEYEEKVLSSQGKALALEKQLWEQLFDLILPKLHELQAFARAAAELDVLSNFAERAETLGYTCPELSQDIGVQIEAGRHPVVERVSQTPFIANPVTLHNQRRMLIVTGPNMGGKSTYMRQVALITLMAHIGCFVPAGRALIGPIDRIFTRIGASDDLASGRSTFMVEMTETANILHNATASSLVLMDEIGRGTSTYDGLSLAWSAAEYLAQQVGAMTLFATHYFELTQLPELMAGVYNVHLDAIEHDDTIAFMHTVQEGAASKSYGLQVAALAGVPNKVIKAAKHKLQQLESRDHQAEGTRTPIQSLLALPEPVENPALTKLSSINPDNLTPKQALDLLYELKRLS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: LANPA_PAEPO
Sequence: MKVDQMFDLDLRKSYEASELSPQASIIKTTIKVSKAVCKTLTCICTGSCSNCK
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.  Lacks antibacterial activity against Gram-negative bacteria.
What are the official names of this protein?
Lantibiotic paenibacillin.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYI_RHOPA
Sequence: MSDKPKTDAAQSGNDYSKTLFLPQTEFPMRAGLPQREPELLKRWEEMDLYGKLRESARGRAKFVLHDGPPYANGNIHIGHALNKILKDVVTKSQQMLGFDSNYVPGWDCHGLPIEWKIEEENYRSKGKPKPNFKDSAAIIAFRKECRAYADKWLNVQREEFKRLGVIGDWDHPYATMNYAAEAQIARELMKFAANGTLYRGSKPVMWSVVEKTALAEAEVEYEDYTSDTVWVKFPVKTGDASTKDASVVIWTTTPWTLPGNRAISFSSKIAYGLYKVTDAPADNWAKTGDLLILADGLAESVFKQARVVAYEKVSDVGADVLKASECAHPLQGLAGGYEFTVPLLDGDHVTDDTGTGFVHTAPGHGREDFDIWMHNARALEARGISSVIPYTVDENGALTEQAPGFTGKRVINDKGEKGDANEAVIQALIARGALLARGKLKHQYPHSWRSKKPVIFRNTPQWFIAMDKDIVDDGVAKPGDTLRARALQAISVTQWVPPAGQNRINGMISGRPDWVISRQRAWGVPIAVFIKDKGDGSVEILQDEIVNQRIAEAFMQEGADAWYAEGAAERFLGDRAAEGWRKVDDILDVWFDSGSTHAFVLEDAQNFPGLAGIRRKVDGGADTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFTLDEQGRKMSKSLGNTTDPAKVIASSGADILRLWVCATDYADDQRIGPEILKNVVETYRKLRNSIRWMLGTLHHYHRDEAVAFADMPELERLMLHQLAEQSATVRAAYAEFDYKTVVASLAAFMNTELSAFYFDIRKDTLYCDPPSSLARKAALTTIDIICDAILKWLAPVLSFTADEAWSMYRPDAEPSVHLTLFPLDLGEYRDDALAKKWTLIRAVRRVVTGALEVERAAKRIGSSLEASPMIYLPEAFMGDIFDVDWAEICITSNAMVEILRGNDTPPADAFRLPELADVAVVVERAQGTKCARSWKILSSVGSDAEYPDVSPRDAQALREWKALGGAAA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH602_AZOSB
Sequence: MAAKQVLFGDDARAKVVQGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKFENIGAQLVKEVASKTADNAGDGTTTATVLAQAIVREGFKFVAAGFNPADLKRGIDKAVAAIVDELKALSKPTTTSKEIAQVGAISANSDADIGDIIAKAIDKVGKEGVITVEDGKSLNNELDVVEGLQFDRGYLSPYFINNPDKQVAELDNPFILLFDKKISNIRELLPVLEQVAKAGSPLLVVAEDVDGEALATLVVNTIRGILKVVAVKAPGFGDRRKAILEDIAILTGGQVIAEEVGLSLEKATLADLGQAKRVEVQKENTTLIDGAGSVEAIKARVSSIDALIAAATSDYDREKLQERKAKLAGGVAVIKVGAATEVELKEKKARVEDALHATRAAVEEGIVPGGGVALLRARAAIKDLKGDNHEQDAGIKIVLRAVEEPLRQIVANAGDEASVVVARVLEGSGNFGYNAANGQYGDLVEQGVLDPAKVTRSALQNAASVAALILTTDALVAEQADDKPATAGLPHGGPGGFGGPEF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIS1_YARLI
Sequence: MESLLTDKQRSDLETSIFGYVSRLTNDEALLSQLAAVLSQPSGSEPVPADTLKANALLLEKKWLSVIRLQRKVMDLETRLEAAEREASSTHKANGLGAGDPKTWLPKTSRFSLLHKQPVNAVSFHPFHSTLASACEDGNIRIWDYELGEIETTIKAHTRGVLDVDFSQPDTGASRDKSHDKPRADVSHAQPRALLVSCSSDLTIRIWDPQNEYANVKTLTGHDHTISAVKFTASGNHVISASRDKTVRVWSVQSGYCVRTVHGHTDWVKSCAALNEEFIFSAGIDHVTRVSEFVSGDGKMTLLGHEHVIEGVAVYPKSAAGCLAKLDKTSSYFVVSWSRDKTIRVWSSRGDPLLILRGHDNWVRGVVLHPAGRYLVSVSDDKTMRCWDLEQGGRCIRVVDAHGHFVTCVAWAPNDVNGRVRCLVATGGVDGQVKVWQ
What is the function of this protein?
Positively regulates the activity of the minus-end directed microtubule motor protein dynein.  Plays a central role in positioning the mitotic spindle at the bud neck during cell division.  Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
What are the official names of this protein?
Nuclear distribution protein PAC1, Lissencephaly-1 homolog, LIS-1, nudF homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat LIS1/nudF family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the plus ends of microtubules and the mitotic spindle poles.
Protein: HSLU_BURCM
Sequence: MSTMTPAEIVSELDKHIIGQAKAKKAVAVALRNRWRRQQVGEPLRQEITPKNILMIGPTGVGKTEIARRLAKLADAPFVKIEATKFTEVGYVGRDVDSIVRDLIEISVKQTREAEMRKVRTKATDQAEDRILDVLLPQPRAVGFGGNADHANDDNNATRQTFRKRLREGQLDDKEVELDLEQPSAGMDIMAPPGMEEMTEQIRSMFSNLGSGKKQRRKVKIKEALKLLTDEEAAKMLNDEEVKTKAVQNVEQNGIVFLDEIDKITSRNNEGSGGEVSRQGVQRDLLPLVEGTTVNTKYGMVKTDHILFIASGAFHLAKPSDLIPELQGRFPIRVELDSLSVEDFEAILDATDASLVKQYQALLATEDVQLEFAADGIRRLAEIAYAVNEKTENIGARRLYTVIEKLLEEVSFSAGNHAGERVTIDAKYVEHALGEVSQDEDLSRYVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOC1_RHIE6
Sequence: MSEALTELASYLGEARGNLIAASQLKYGELTLTATGENLIPLLTFLRDDAKCGFVNLIDICGVDWPQRELRFDVVYHLLSPKKNLRIRVKVATDEDTPVPSACGLYPGADWFERETWDMYGVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDDAAKRVVYEPVELKQEFRNFDFMSPWEGTEYVLPGDEKAKQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C 1, NADH dehydrogenase I subunit C 1, NDH-1 subunit C 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IF3_BACCZ
Sequence: MMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMD4_CAEEL
Sequence: MVQESTMICVDNSEYMRNGDFQPTRLQSQQDAVNLVTQCKLRANPENAVGILSMANSVQVLSSLSTEQGRLMMKNHSIEPFGKCNFIAGIKIAHLALKHRQNRNHKMRVVLFIGSPLEEIEMNELVKIAKKMKKEKVLCDVIMFGENESDGHEKFSTFVDTLNGKEGSGSSLIVVPQGSSLTDALLQSSVCKNEDGQAAFGGGGNGMDNAFGMDVENDPDLALALRVSMEEERARQAAAAAANGGAADSGADAEVAAAAAAVPLEEMDMGAMTEEQQLEWALRLSMQENAPAEQPQVQHEQMDVDGAPAVGGDNLDDLMNNPELLQQIVDDLPAANAEKDDDKEKK
What is the function of this protein?
Binds and presumably selects ubiquitin-conjugates for destruction (By similarity).  Required for protein degradation and ubiquitin-proteasome system (UBS) function and regulates proteasomal subunit expression (PubMed:20453865, PubMed:22105480, PubMed:26828939).  Involvement in UBS might be cell type specific (PubMed:20453865).  Regulator of the autophagy-lysosome pathway that may confer resistance to autophagy by regulating the expression of autophagy-related proteins such as lgg-1, and by regulating lysosome formation, possibly by modulating elt-2 activity (PubMed:26828939).  Required for fertility, sperm production, and sex determination through regulation of tra-2 protein (PubMed:17050737).  Plays a role in the elimination of paternal mitochondria in fertilized eggs (PubMed:22105480).
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 4, 26S proteasome regulatory subunit rpn-10.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S5A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.