PharMolix/UniProtQA huggingface dataset:
Protein: IF2P_DICDI
Sequence: MGPKQRVRKDNYWDSGEADKDREEAEKLHKKGQQQSDSDSDSDDIPISKKKPTSKFAPVDESSSESEESSSEEEVQKKPSKPAAKQSKKVAPTNNKKKPVVESSSSEEEESESESEESSEEDTKKKPSKPAAKQSKKVAPTNNNNNKKKPVVESSSEESESESEESSSEEDTKKKPSKPAAKQNKKAPAKKAAAVESSSESEEESSSSEEEEKPTKPTQNNNNKKNNAKKPPAAKPSAAKQQAKKPAPKKPEEPEVLSGFLLKQRQEEERIAREKEEKRIREEEEKKRAAEQKIIDDEKARLKSIENSKKRAEKKEKQAGAAAEADRMAKLAKLGVNISAVGEKKEKSTNKTKSGGKKQNQVSSITESVEKLKIEEPTSAPKDDVVEVMDSWDNDDYETVEEIQKKKEEEAKRKEEEEEAQRLAAKEEKKKAKAAAAAAAAALIPTTDPTTTFADKSYRSPIICILGHVDTGKTSLLDKIRNTNVQGGEARGITQQIGASFIPVDAIKEQTKSFAEKIKMDFKLPGLLLIDTPGHESFNNLRSRGSGLCDLAILVIDIMHGLQAQTLESINLLRMRKTPFIVALNKVDRIYDWKPCVNTDFKEAYKIQSKSAAQEFDYKVKDIIAALAGQELNAELYWRNKDHRKYVSLVPTSANTGEGISDLMLVVIQLMQKLMLDKVEFTNQLQCTLLEVKVIEGFGTTIDVVLVNGTLNEGDKIVVSGFNGPIETSIRSLLTPPPLRESRVKSQFINHKSIRAAMGIKIVAPGLEKAVPGTSLHVVGPNDDIEKIRAEAKREVDSVLNDVETSGIGVSVQASTLGSLEAFLNFLKKIKIPVANVAIGPVHKKHIMNASIMLDKDPKYAILLAFDVKIEESAIQAANEMKVQVLSDETIYLFEEKLKKHFGAIKEKLRAETASICVWPCILEVTNVFRNSNPILVGVRVKEGTLRIGTPICVPESNCADVGKVIGIKLNEKDVTLAKKDDVVSVAIDDNNTKTTIYRHFDDKKQWMSKITRESLDALKEGWSEDLTKQDIQLLKFMKTVYKIQ
What is the function of this protein?
Plays a role in translation initiation.  Translational GTPase that catalyzes the joining of the 40S and 60S subunits to form the 80S initiation complex with the initiator methionine-tRNA in the P-site base paired to the start codon.  GTP binding and hydrolysis induces conformational changes in the enzyme that renders it active for productive interactions with the ribosome.  The release of the enzyme after formation of the initiation complex is a prerequisite to form elongation-competent ribosomes.
What are the official names of this protein?
Eukaryotic translation initiation factor 5B, eIF-5B, Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DENR_PICGU
Sequence: MTEVEPKSVLYCGVCSFPPEFCEFGGSFKRCKEWLEQNDKELYEKLYSEDALANATSTLSIDKEQKIAKELEKKQAKEEAKQERELKKQLASKVTIKRIERNKRKHVIAISGLEVFDIDMKKLSKTFASKFATGASVTKNAEKKDEIIVQGDVSDEARAYIEKLLEEKGLNEVKVEQIDDKKKKKAAEAAEAAAAATGNKK
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_ECOUT
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL33_ECO57
Sequence: MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: EFTU_SHIFL
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPD_PICAN
Sequence: MTAMDRLDHVSNQLAAKRQKKNPEGKPFRITVVGSGNWGSTIAKVVAENAKELPEEFHQIVKMWVFEEEVDGRKLTEIINTDHENVKYLPDVKLPDNIVAIPDIVDACADADIIIFNIPHQFLPKILAQLKGKVNPKARAISCLKGLEVTKDGCKLLSNYITEELGIYCGALSGANLAPEVARQKWSETTVAYRIPQDFRGEGKDVDQSVIRNLFHRPYFHVRVIDDVAGVSLSGALKNVIAMAAGFVEGLGWGDNAKSAVMRIGLVEMIKFAHMFFEDCQSTTFTHESAGVADIITTCAGGRNVRVGRYMAEHKVSGFEAEKVLLNGQSCQGLHTTREVYELLAAKNVIDEFPLFKATYQIIYEGLPMEKLPELLEASED
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Protein: RU1C_PLACH
Sequence: MPKYYCEYCDIYLTHSSPVGRRQHNQGRKHISAKIEYFQNLLREEGITPQNFLGFLGSQAYNNILSNPMMNNFMHGNYNGYMKYSPMRNYHHSNRNPNYQHSVGMHNNKYSRAGYVPPGANKYPNNNFHNNKRISNTPKPYNNYTNKPITNSPYKNDKQDYRNNNENSNNFSNYQMNKDNSNFVNKNSEQPN
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PMP21_CHLPN
Sequence: MVAKKTVRSYRSSFSHSVIVAILSAGIAFEAHSLHSSELDLGVFNKQFEEHSAHVEEAQTSVLKGSDPVNPSQKESEKVLYTQVPLTQGSSGESLDLADANFLEHFQHLFEETTVFGIDQKLVWSDLDTRNFSQPTQEPDTSNAVSEKISSDTKENRKDLETEDPSKKSGLKEVSSDLPKSPETAVAAISEDLEISENISARDPLQGLAFFYKNTSSQSISEKDSSFQGIIFSGSGANSGLGFENLKAPKSGAAVYSDRDIVFENLVKGLSFISCESLEDGSAAGVNIVVTHCGDVTLTDCATGLDLEALRLVKDFSRGGAVFTARNHEVQNNLAGGILSVVGNKGAIVVEKNSAEKSNGGAFACGSFVYSNNENTALWKENQALSGGAISSASDIDIQGNCSAIEFSGNQSLIALGEHIGLTDFVGGGALAAQGTLTLRNNAVVQCVKNTSKTHGGAILAGTVDLNETISEVAFKQNTAALTGGALSANDKVIIANNFGEILFEQNEVRNHGGAIYCGCRSNPKLEQKDSGENINIIGNSGAITFLKNKASVLEVMTQAEDYAGGGALWGHNVLLDSNSGNIQFIGNIGGSTFWIGEYVGGGAILSTDRVTISNNSGDVVFKGNKGQCLAQKYVAPQETAPVESDASSTNKDEKSLNACSHGDHYPPKTVEEEVPPSLLEEHPVVSSTDIRGGGAILAQHIFITDNTGNLRFSGNLGGGEESSTVGDLAIVGGGALLSTNEVNVCSNQNVVFSDNVTSNGCDSGGAILAKKVDISANHSVEFVSNGSGKFGGAVCALNESVNITDNGSAVSFSKNRTRLGGAGVAAPQGSVTICGNQGNIAFKENFVFGSENQRSGGGAIIANSSVNIQDNAGDILFVSNSTGSYGGAIFVGSLVASEGSNPRTLTITGNSGDILFAKNSTQTAASLSEKDSFGGGAIYTQNLKIVKNAGNVSFYGNRAPSGAGVQIADGGTVCLEAFGGDILFEGNINFDGSFNAIHLCGNDSKIVELSAVQDKNIIFQDAITYEENTIRGLPDKDVSPLSAPSLIFNSKPQDDSAQHHEGTIRFSRGVSKIPQIAAIQEGTLALSQNAELWLAGLKQETGSSIVLSAGSILRIFDSQVDSSAPLPTENKEETLVSAGVQINMSSPTPNKDKAVDTPVLADIISITVDLSSFVPEQDGTLPLPPEIIIPKGTKLHSNAIDLKIIDPTNVGYENHALLSSHKDIPLISLKTAEGMTGTPTADASLSNIKIDVSLPSITPATYGHTGVWSESKMEDGRLVVGWQPTGYKLNPEKQGALVLNNLWSHYTDLRALKQEIFAHHTIAQRMELDFSTNVWGSGLGVVEDCQNIGEFDGFKHHLTGYALGLDTQLVEDFLIGGCFSQFFGKTESQSYKAKNDVKSYMGAAYAGILAGPWLIKGAFVYGNINNDLTTDYGTLGISTGSWIGKGFIAGTSIDYRYIVNPRRFISAIVSTVVPFVEAEYVRIDLPEISEQGKEVRTFQKTRFENVAIPFGFALEHAYSRGSRAEVNSVQLAYVFDVYRKGPVSLITLKDAAYSWKSYGVDIPCKAWKARLSNNTEWNSYLSTYLAFNYEWREDLIAYDFNGGIRIIF
What are the official names of this protein?
Probable outer membrane protein pmp21, Polymorphic membrane protein 21.
What is the protein family that this protein belongs to?
Belongs to the PMP outer membrane protein family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell outer membrane; Peripheral membrane protein; Extracellular side.
Protein: RL24_CROS8
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: HIS1_ECO55
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_STRR6
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRRGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: PURU2_ARATH
Sequence: MIRRVSTTSCLSATAFRSFTKWSFKSSQFHGESLDSSVSPLLIPGFHVFHCPDVVGIVAKLSDCIAAKGGNILGYDVFVPENKNVFYSRSEFIFDPVKWPRRQMDEDFQTIAQKFSALSSVVRVPSLDPKYKIALLLSKQDHCLVEMLHKWQDGKLPVDITCVISNHERAPNTHVMRFLQRHGISYHYLPTTDQNKIEEEILELVKGTDFLVLARYMQLLSGNFLKGYGKDVINIHHGLLPSFKGRNPVKQAFDAGVKLIGATTHFVTEELDSGPIIEQMVERVSHRDNLRSFVQKSEDLEKKCLMKAIKSYCELRVLPYGTQRTVVF
What is the function of this protein?
Deformylase involved in photorespiration.  Prevents excessive accumulation of 5-formyl tetrahydrofolate (THF), a potent inhibitor of the Gly decarboxylase/Ser hydroxymethyltransferase complex.
What are the official names of this protein?
Formyltetrahydrofolate deformylase 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PurU family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ZN880_HUMAN
Sequence: MLRRGHLAFRDVAIEFPQEEWKCLDPAQRTLYREVMVENYRNLVFLGICLPDLSVISMLEQRRDPRNLQSEVKIANNPGGRECIKGVNAESSSKLGSNAGNKSLKNQLGLTFQLHLSELQLFQAERNISGCKHVEKPINNSLVSPLQKIYSSVKSHILNKYRNDFDDSPFLPQEQKAQIREKPCECNEHGKAFRVSSRLANNQVIHTADNPYKCNECDKVFSNSSNLVQHQRIHTGEKPYKCHECGKLFNRISLLARHQRIHTGEKPYKCHECGKVFTQNSHLANHHRIHTGEKPYKCNECGKVFNRNAHLARHQKIHSGEKPYKCKECGKAFSGGSGLTAHLVIHTGEKLYKCNKCGKVFNRNAHLTRHQRIHTGEKPYECKECGKVFRHKFCLTNHHRMHTGEQPYKCNECGKAFRDCSGLTAHLLIHTGEKPYKCKECAKVFRHRLSLSNHQRFHTGEKPYRCDECGKDFTRNSNLANHHRIHTGEKPYKCSECHKVFSHNSHLARHRQIHTGEKSYKCNECGKVFSHKLYLKKHERIHTGEKPYRCHECGKDFTRNSNLANHHRIHTGEKPYR
What are the official names of this protein?
Zinc finger protein 880.
Protein: RS211_BURO1
Sequence: MTIIRVKENEPFEVAMRRFKRTIEKNGLLTELRAREFYEKPTAERKRKKAAAVKRHYKRIRSQTLPKKLY
What are the official names of this protein?
30S ribosomal protein S21 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: HISZ_THEP3
Sequence: MIYLPDGVQDFLPEEYKFKRKIEEKFREVFIKFGYQEIMPPTFEYSDNFSVLFDENNLYRFFDKKGNILALRPDVTTQIARIVSTKLKGSFPLKLCYVANVYRYDDPQVGKMREFTQAGIELIGTNHEESDAEIIAVAIEALKSVGIKDFKVDVGQVEFFKRVVEDLELQNEEINLLREFLQQKNQSAIEEFINDKGIRGKKAKFLSELPLLFGGEEVLKRAKELYDTPKLGETIDYLERVYRILKDFGMEEYISFDLGMVQNLNYYTGIIFRCFVKGIGYAICTGGRYDGLLGIFGEHIPATGFAISVERSMLALQKQKKDIIDKSWRVLIKYKENLRSNAYKKATLLRGEGKIVEMYSYEKAKHVDENSFDEIIDMEE
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_DESA1
Sequence: MARVFHVAEKVEIPENVAVEVDGLRVTVKGPKGIITRDFSHARGVFIRLEDRVVIVETFVADRKQKALVGTIAAHIRNMITGVVRGYRYKLKIIFSHFPITVSVDEKNKVVRIRNFMGEKSDRIAKIYGNVKVKVSGEDIIIEGVDIEEVGLTAASIERATRVTDRDRRVFMDGIYIYEKGEAL
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: YL812_MIMIV
Sequence: MANYIPNDWRDNDITNRYIRYRRTGPHKTTGPTTVYKKLECTKKIERWGIPLTKYRVGIATLEIPPESKLVRLLYGTFGDIRFDQAFVKKIEYINDKDKYISDDYVCTSEIYNLENYPLNFKVGQMVNFIDNDQLNENQHDLEGPGISAYFSKKESKN
What are the official names of this protein?
Uncharacterized protein L812.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L223/L227/L812 family.
Protein: METK_SHEWM
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEVTTSAWVDIEEITRNTVREIGYTHSDMGFDADSCAILNVIGKQSPDINQGVDRADPKEQGAGDQGLMFGYANNETDVFMPAPITYSHMLVKRQSEVRKDKTLPWLRPDAKSQVTFAYNSDGSIAGIDAVVLSTQHSEDVTQADLIEGVMESIIKPVLPAKWLSKETKYFINPTGRFVIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCELQVSYAIGVAEPTSISIETFGTAKVAEELLIDLVRRHFDLRPYGLTEMLNLARPIYKSTAAYGHFGREEFPWEATDKVEALRADAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPE_MOUSE
Sequence: MAGRGGRVLLALCAALVAGGWLLTAEAQEPGAPAAGMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNLKKIVDQNSKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRSGTAHEYSSCPDDAIFQSLARAYSSFNPVMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKSYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVDGIDHDVTSAKDGDYWRLLAPGNYKLTASAPGYLAITKKVAVPFSPAVGVDFELESFSERKEEEKEELMEWWKMMSETLNF
What is the function of this protein?
Sorting receptor that directs prohormones to the regulated secretory pathway.  Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
What are the official names of this protein?
Carboxypeptidase E, CPE, Carboxypeptidase H, CPH, Enkephalin convertase, Prohormone-processing carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein. Secreted. Note=Associated with the secretory granule membrane through direct binding to lipid rafts in intragranular conditions.
Protein: CYB6_GOSBA
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLGVLTASFGVTGYSLPRDQIGYWAVKIVTGVPEAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GCSH_PHOV8
Sequence: MEFPSNVKYTKEHEWIRVEGDIAYVGITDYAQEQLGDIVFVDITTEGETLEKDEVFGTIEVVKTISDLFLPVSGEVLEQNEALADNPELVNQDPYGKGWLIKIKPNDSNDVNDLLDAEGYKALVNE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: EXGA_ASPCL
Sequence: MLSRLSQTALVALSLMTVLTEAVPSRMRIQTRDSVNYQSEIVRGVNLGGWLVLEPWITPSIFENGGGAAVDEWTLAEVLGKDKARAILSQHWSSFITQDDFNQIAQAGMNHVRIPVGYWAVSAPDEPYVDGQLEFLDNAISWARAAGLKVMIDLHGAPGSQNGFDNSGRKGPIAWQQGDTVARTVDAFKALAERYLPESDVVTAIEAVNEPNIPGGVNEGQLKEYYNQVLEVVHSINPDAGVFLSDGFLATASWNGYANGENVVMDTHHYHMFDNTLISLDINAHVRAACEFGNQIKGSDKPVVVGEWTGALTDCTKHLNGKDIPTRYEGQWANSPRYGDCGNKRQGSSSGLSEQERSDTRRFIEAQLDAYEGKNGWLFWTWKTEGAPGWDMQDLLANGLFPNPPTERQYGNQCA
What is the function of this protein?
Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall.  It could also function biosynthetically as a transglycosylase (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase A, Exo-1,3-beta-glucanase 1, Exo-1,3-beta-glucanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: APT_ACAM1
Sequence: MDLKSLIRDIPDFPKPGILFRDITTLLQNPDGLRYVIDQFTEDYREQSIDYVVGIESRGFIFGAPLAYQLGAGFVPVRKPGKLPAAIHAQEYELEYGTDRLEIHQDACPAGSRVLVVDDLLATGGTAAATAQLLAPLNCTLVGFGFIIELTGLAGRQKLPDCHINALVEY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYCD_HUMAN
Sequence: MTLLGSEHSLLIRSKFRSVLQLRLQQRRTQEQLANQGIIPPLKRPAEFHEQRKHLDSDKAKNSLKRKARNRCNSADLVNMHILQASTAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPVDSAVKEAIKGNQVSFSKSTDAFAFEEDSSSDGLSPDQTRSEDPQNSAGSPPDAKASDTPSTGSLGTNQDLASGSENDRNDSASQPSHQSDAGKQGLGPPSTPIAVHAAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQQHRFSYLGMHQAQLKEPNEQMVRNPNSSSTPLSNTPLSPVKNSFSGQTGVSSFKPGPLPPNLDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPFQDCSGNPVPNFGDITTVTFPVTPNTLPNYQSSSSTSALSNGFYHFGSTSSSPPISPASSDLSVAGSLPDTFNDASPSFGLHPSPVHVCTEESLMSSLNGGSVPSELDGLDSEKDKMLVEKQKVINELTWKLQQEQRQVEELRMQLQKQKRNNCSEKKPLPFLAASIKQEEAVSSCPFASQVPVKRQSSSSECHPPACEAAQLQPLGNAHCVESSDQTNVLSSTFLSPQCSPQHSPLGAVKSPQHISLPPSPNNPHFLPSSSGAQGEGHRVSSPISSQVCTAQMAGLHSSDKVGPKFSIPSPTFSKSSSAISEVTQPPSYEDAVKQQMTRSQQMDELLDVLIESGEMPADAREDHSCLQKVPKIPRSSRSPTAVLTKPSASFEQASSGSQIPFDPYATDSDEHLEVLLNSQSPLGKMSDVTLLKIGSEEPHFDGIMDGFSGKAAEDLFNAHEILPGPLSPMQTQFSPSSVDSNGLQLSFTESPWETMEWLDLTPPNSTPGFSALTTSSPSIFNIDFLDVTDLNLNSSMDLHLQQW
What is the function of this protein?
Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence.  Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes.  Plays a crucial role in cardiogenesis, urinary bladder development, and differentiation of the smooth muscle cell lineage (myogenesis) (By similarity).
What are the official names of this protein?
Myocardin.
What are the subcellular locations of this protein?
Nucleus.
Protein: BP4C_BRANA
Sequence: MKKSLQLSFTFLIISIILSQGMMADAQKKNCPRKIPIKGSYCAPTICLDKCKKQHGTVGSCAEEKGFCNCACK
What are the official names of this protein?
Protein BP4C.
Protein: IDI_SALDC
Sequence: MTEEHVVLLDEQDKPSGTLEKYAAHTLNTPLHLAFSCWLFNEDGQLLVTRRSLSKKAWPGVWTNSVCGHPQQGETTEEAIIRRCRFELGVEITDLTPVYPHFSYRATDPNGIVENEVCPVFAARATSVLQVNSEEVMDYQWSEFKSVWKSLLATPWAFSPWMVMQASDEQARERLLNYCQR
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_THESQ
Sequence: MNVAILLAAGKGERMSENVPKQFLEIEGRMLFEYPLSTFLKSEAIDGVVIVTRREWFEVVEKRVFHEKVLGIVEGGDTRSQSVRSALEFLEKFSPSYVLVHDSARPFLRKKHVSEVLRRARETGAATLALKNSDALVRVENDRIEYIPRKGVYRILTPQAFSYEILKEAHENGGEWADDTEPVQKLGVKIALVEGDPLCFKVTFKEDLELARIIAREWERIP
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.