PharMolix/UniProtQA huggingface dataset:
Protein: RBL_CAMSI
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TRHBN_NOSSN
Sequence: MSTLYDNIGGQPAIEQVVDELHKRIATDSLLAPIFAGTDMAKQRNHLVAFLGQIFEGPKQYGGRPMDKTHAGLNLQQPHFDAIAKHLGEAMAVRGVSAEDTKAALDRVTNMKGAILNK
What are the official names of this protein?
Group 1 truncated hemoglobin GlbN, Truncated Hb, Cyanoglobin.
What is the protein family that this protein belongs to?
Belongs to the truncated hemoglobin family. Group I subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: SCO22_RICFE
Sequence: MKMQSNVIKIIIVISLLIGVGALYLLLSLRTPEKPLAGQVNIYEDNVKIGGDFELIDQNGEIFNSDELKGNLSLIYFGFTSCPDICPTSLNKMTEIVEILNKHKIDILPVFITIDPKRDTPIVLKEYLKHFHPKFIGLTGNEQQIKGVTDKFKVFYARVNGDDDDPNYMLDHSSFTYLIDANGKYLKHFYLDSSPKEIMEFLKGN
What are the official names of this protein?
SCO2-like protein RF_0960.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
Protein: PYRE_LEGPH
Sequence: MNHTKSSFIKLALECQVLKFGEFTLKSGRISPYFFNAGLFYHGDSLRKLGQFYAKTLLEQEVSFEHLFGPAYKGIPLATATAVALAELGRDITVTFNRKEVKTHGEGGQLIGSPLTGRTVIIDDVITAGTAFRESQTLIKENGGILRGVIIALDRCERGLTEKSTLSEIREQGIEVYSIINLFDLIEFLKNDNQYEQVQKLESYQERYGA
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LEXA_STAAE
Sequence: MRELTKRQSEIYNYIKQVVQTKGYPPSVREIGEAVGLASSFTVHGHLSRLEEKGYIEGDPTKPRAIEIVSDQTNDNINMEETIHVPVIGKVTAGVPITAVENIEEYFPLPEHLTSTHNSDIFILNVVGDSMIEAGILDGDKVIVRSQTIAENGDIIVAMTEEDEATVKRFYKEKNRYRLQPENSTMEPIYLDNVAVIGKVIGLYREM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SYP_MYCBO
Sequence: MITRMSELFLRTLRDDPADAEVASHKLLIRAGYIRPVAPGLYSWLPLGLRVLRNIERVIRDEMNAIGGQEILFPALLPRAPYETTNRWTQYGDSVFRLKDRRGNDYLLGPTHEELFTLTVKGEYSSYKDFPLTLYQIQTKYRDEARPRAGILRAREFVMKDSYSFDIDAAGLKAAYRAHREAYQRIFDRLQVRYVIVSAVSGAMGGSASEEFLAESPSGEDAFVRCLESGYTANVEAVVTARPDTLPIDGLPEAVVHDTGDTPTIASLVAWANEADLGRTVTAADTLKNVLIKVRQPGGDTELLAIGVPGDREVDDKRLGAALEPADYALLDDDDFAKHPFLVKGYIGPKALRENNVRYLVDPRIVDGTSWITGADQPGRHVVGLVAGRDFTADGTIEAAEVREGDPSPDGAGPLVMARGIEIGHIFQLGSKYTDAFTADVLGEDGKPVRLTMGSYGIGVSRLVAVVAEQHHDELGLRWPSTVAPFDVHLVIANKDAQARAGATALAADLDRLGVEVLLDDRQASPGVKFKDAELLGMPWIVVVGRGWADGVVELRDRFSGQTRELVAGASLATDIAAAVTG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_PARMW
Sequence: MPDHGMSRLLVAAFYAFTPLDDDQREALLSALPTQASHGAVLGSVLVAKEGVNGTISGPEQGVEGLLEHLQEQLKLGEQHFERLEVKRSWAERSVFRRFKARRKKEIVTMGVTGVDPRANVGTYVDPEDWNGLVDDPDTLVIDTRNHYETAIGSFDGAIDPGTDSFRDFPHWAETKLRPLIDETAPKRIAMFCTGGIRCEKASSYLQHQGFGEVHHLRGGILKYLEQVPEEESRWRGECFVFDQRVALNHQLEPGEHSLCHACGLPLSPEQRSLPSYIKGVQCLHCIDRFSESDRQRFAMRQRQMDQLSSASSKKSDDFSL
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: YCF12_GRATL
Sequence: MINWQVIGQLTSLAMIVLVGPAVIVVLSLRKGDL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ISPH_HELHP
Sequence: MKVKFAKKYGFCFGVKRAIRIAERNQHATTFGPLIHNSREIERLQKDFDVSLSRSLEEAQKFKSVIVRTHGITKDDLQVLKEHHTHIIDATCPFVTKPQQIVEKMSQEGYQIIIFGDNSHPEVKGVASYGDDVAIIANIDELKHLTLKKKVALVSQTTKQPEHFGKIAALLVSLVNECRIFNTICSATFENQFAVDELSREADIMVIVGGKNSSNTKQLFKIAKEYCTDSYLIEDENEIDNTWFVGKELCGITAGASTPDWIISRVQEKIEQI
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RL32_STREM
Sequence: MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSLKGYYKGRKIAKANAAE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MIAB_RHOP5
Sequence: MDQPRKLHIKSFGCQMNVYDAQRMVDALAPEGFVETQSADDADLVILNTCHIREKAAEKVYSELGKLRLLKQDAASHGRRFEIAVAGCVAQAEGAEIIRRQPAVDVVVGPQSYHHLPELLEKARRDGRALETEFPIEDKFGVLPPPRPDAIRARGVSAFVTVQEGCDKFCSFCVVPYTRGAEMSRPVAKILDDVKRLIDNGVREITLIGQNVNAYHGEGPDDRPWTLGALLRHLASVPGVARLRYSTSHPLDVDDELIAAHRELPGLMPFVHLPVQSGSDAILAAMNRRHSADDYRRVIDRFRQADPSIAFSSDFIVGFPGETDRDFEATLALVTQIGYAGAYSFKYSPRPGTPAAELQEMVAPAVMDQRLEQLQGLIDSQQAAFNRASIGTTVDVLFERAARHPGQIVGRTAYLQPAHVMAADDIVGQVLPVTIHSLERYSLIGELVKPQPARPPKPLPVTTGA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_CHLSY
Sequence: MHELSIAHNIVTIASDAAAEAGVDRISAVHLRIGALAGVVADALRFSFAIAAEGTPLAGAELIIEEVPVVVFCPDCNAEVTLTNPRLFRCPRCDRPCGQIVHGRELELVALETP
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: CN165_HUMAN
Sequence: MFTLLLSNYYSRLEGWMMDNNFSHHWKGMFPTETESTVFCLFVYLFIFVFETASGFVAQTGVHWCNLGSLQPLPPGFKRFSCLSLPSSLDYRHAPPCLANFYIFSGDRVSPCWPDWS
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00596.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SCRN3_MOUSE
Sequence: MEPYSCDTFVALPPATVGNRVIFGKNSDRLFDEVQEVIYCPAAVHNDLEKRLKCTYIEVDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAVWGREDISKEEALLGMDLVRLGLERADTAEKALDVIVDLLEKYGQGGNCAEGKEFSYYNSFLIADRNEAWILETSGKYWAAERVQGVRNISNQLSITTKIDREHPDMRNYAKQRGWWDGKEEFDFTAAYSYIDTAAMMTSPSRYCQGYKLLDKHRGNITFETMMEILRDRPSGINMKGEFLTTASMVSVLPQDPSLPCIHLFTATPHPERSVFKPFIFVPHISPLLDTKSPTFEPERPVAKKPYVKPDRRHPLYQKHQEALEMISNSKEKGKTILDKMRKLEKAVSEEIESILQSGHLDEEKTVNLFPQYVKDEIKIYQSNISS
What are the official names of this protein?
Secernin-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C69 family. Secernin subfamily.
Protein: GLO2_GLOVI
Sequence: MLVHRLNALKDNYVFVLEDEAARTAAVVDPAEARPVLEALVRLGLKLVAIFNTHHHHDHVGGNRELLEAYPGIAVYASRRDRGRIPGQTVELEDGDTVAFGCERARVIFVPGHTHGHIAYHFAGCGHLFCGDTLFAGGCGRLFEGTARQMQHSLGRLRELPGETQVWCAHEYTLGNLRFAHTLEPDNAELAERLRTVEVLRARKIATVPSTMAAERATNPFLRWESRQLQRAAGAIEPEEVFAHLRALKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: DGTP_SALCH
Sequence: MASIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKEQNRLEEYGLDALTGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTHDRCVVSSLRLQEGEENLNDIRRKVRQDICHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGPVPDSHHYLMKKPGYYLSEEKYIARLRKELQLAPYSRFPLTWIMEAADDISYCVADLEDAVEKRIFSVEQLYHHLYHAWGHHEKDSLFELVVGNAWEKSRANTLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPQIFAGTFNQALLEDASGFSRLLELYKNVAVEHVFSHPDVEQLELQGYRVISGLLDIYQPLLSLSLNDFRELVEKERLKRFPIESRLFQKLSTRHRLAYVEVVSKLPTDSAEYPVLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: RL23_CLOBH
Sequence: MKLTNYDIIRRPLITEKTMASMADKKYTFVVDIHANKSQIKNAIETIFDVKVEDVKTARIMGKTKRVGVHIGKRPDYKKAIVKLTEDSKTIEFFEGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GCH1L_NEIMA
Sequence: MVLRRDFLTWCNETLQTALFKDYAPNGLQVEGREYIGKIVTSVTASRAAIDFAVEQKADLLLVHHGMFWKNELPTVTGWKKERIAALLRHDINMAGYHLPLDAHPTLGNNAQLADRLGFATEKRFGEQNLLNSGSLKQAKTLGALAAHIETVLQRKPVVIGKPEREIRRVAWCSGGAQGFFQTAIDEGVDLYLTGEISEAQYHLANETGTAFISAGHHATERYGVRALAESAAEVFGLEVCHFDENNPA
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: AIM11_YEAS7
Sequence: MIEEKKERKKRRVLQMARFYGAAAFTLITMRLISRAIKVRKYVPSIFQQNYKLPPFSQRNEAMSALTYASAASIGTFSTLIFGFCWALDISTAREFVFKTREFMGVPQALETDTSMDEETSKLTKQLQDLLSSENNK
What are the official names of this protein?
Altered inheritance of mitochondria protein 11, Genetic interactor of prohibitins 8.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RADA_MYCS2
Sequence: MAGSKIRSQYRCSECQHVAPKWVGRCANCGTWGTVDEVAVLAGNNKLNGAARRSVAPTSPAVPITSIDPGVTRHYPTGVSELDRVLGGGLVAGSVTLLAGDPGVGKSTLLLEVANRWAHSGKRALYLSGEESAGQIRLRAERTGCTHDQVYLAAESDLQIALGHIDEVKPSLVVVDSVQTMSTTEADGVTGGVTQVRAVTTSLTAYAKAAVGDPAVAMILVGHVTKDGAIAGPRSLEHLVDVVLHFEGDRASSLRMVRGVKNRFGAADEVGCFQLHDNGIECVSDPSGLFLDQRPLAVPGTAVTVTLDGKRPMIGEVQALVSPPAGPPRRAVSGIDSARAAMIGAVLQTRCRMPINSNDLYLSTVGGMRLTDPSADLAVALAIASAYFDIAMPMKAIAIGEVGLAGDLRRVTGMDRRLSEAARLGFTTAVVPPGVTSAPAGLKVVAADNIRAAVQTMREIAIAGAQ
What is the function of this protein?
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks.  Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster.  Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB.  Does not have RecA's homology-searching function (By similarity).  Also inhibits the diadenylate cyclase activity of DisA (PubMed:23760274).
What are the official names of this protein?
DNA repair protein RadA, Branch migration protein RadA.
What is the protein family that this protein belongs to?
Belongs to the RecA family. RadA subfamily.
Protein: Y1595_HALSA
Sequence: MTGTAPVSRRQYLGTAGAIIGTTAGCLTGADASIHVLAAGSLTSTIEDHIRPAFEDATDHTLRPEYHGSTTLLQLISDGTKHPDVAISADATLLRTRLFDAHADWALEFASNRLGICYVPSTPLGRRLAAGTPWWRAAVDAAPDTIAVSDPALDPLGYRTLMAFTLAATAHDAPDLRADLDPATVTKPSESQLLADVETGNHAAAVVYENMALDHDLPFLGFPDAYNFAAPERADHYASATYTTDDGTRIHGRPITYATTVLNDASNTAGGRAFVRFLAANPDMVRDAGLAVPESLPTHQGALPDALER
What are the official names of this protein?
Uncharacterized solute-binding protein VNG_1595C.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family. WtpA subfamily.
Protein: FLA2_TREPH
Sequence: MIINHNMSAMFAQRTLGNTNLSVQKNMEKLSSGLRINRAGDDASGLAVSEKMRSQIRGLNQASTNAQNGISFIQVAESYLQETTDVIQRIRELSVQSANGIYSAEDRMYIQVEVSQLVAEIDRIASHAQFNGMNMLTGRFARETGENTVTASMWFHIGANMDQRTRAYIGTMTAAALGVRDVGDESILNIDDPEKANRAIGTLDEAIKKINKQRADLGAYQNRLEYTVIGVNVAAENLQAAESRIRDVDMAKEMVDYTKNQILVQSGTAMLAQANQATQSVLSLLR
What is the function of this protein?
Component of the core of the flagella.
What are the official names of this protein?
Flagellar filament 33 kDa core protein, Class B.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm.
Protein: GUN2_ORYSJ
Sequence: MARGGGAAGVSMAHHLGIALVVLVFAAMAQVARGGGGGHDYGMALSKSILYFEAQRSGVLPGSQRIAWRANSGLADGKANGVDLVGGYYDAGDNVKFGLPMAFTVTMMAWSVIEYGEEMAAAGELGHAVEAIKWGTDYFAKAHPEPNVLYAEVGDGDSDHNCWQRPEDMTTSRQAYRLDPQNPGSDLAGETAAAMAAASLVFRSSNPGYADQLLQHSKQLFDFADKYRGRYDNSITVARNYYGSFSGYGDELLWASAWLYQASDDRRYLDYLANNADALGGTGWSINQFGWDVKYPGVQILAAKFLLQGKAGEHAGVLQGYRRKADFFACSCLGKDAADNVGRTPGGMLYHQRWNNIQFVTSASFLLAVYSDHLAGGAVRCSGGGGAVAGAAELLAFAKSQVDYILGSNPRGTSYMVGYGAVYPRQAHHRGSSIASIRASPSFVSCREGYASWYGRRGGNPNLLDGAVVGGPDEHDDFADERNNYEQTEAATYNNAPLMGILARLAAGHGARARGRLGQSLQHGIAANHTSLPHGANHQHASPVEIEQKATASWEKDGRTYHRYAVTVSNRSPAGGKTVEELHIGIGKLYGPVWGLEKAARYGYVLPSWTPSLPAGESAAFVYVHAAPPADVWVTGYKLV
What is the function of this protein?
Hydrolyzes 1,4-beta-glycosyl linkages of 1,4-beta-glucans and 1,3-1,4-beta-glucans.  Possesses broad substrate specificity for hemicelluloses of type II cell walls.  Substrate preference is carboxymethyl-cellulose > 1,3-1,4-beta-glucan > lichenan > arabinoxylan > phospho-swollen cellulose > xylan > glucomannan.  May participate in lateral root development.
What are the official names of this protein?
Endoglucanase 2, Endo-1,4-beta glucanase 2, OsCel9A, OsGLU5.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR5_PROM4
Sequence: MDYKTAGVDVKAGRAFVDLIKTSVNETSRPEVIGGIGGFGGFMRLPHGLENPVLVAGTDGVGTKLELAQDYHAHFGVGIDLVAMCVNDVITSGAEPLLFLDYIATGKLAPKDLSEVVKGIAEGCKKSNCVLLGGETAEMPGFYSKGRYDLAGFCLAVVEEKKIIDGSTIKAGDQIIGVQSNGLHSNGFSLVRKVLGMSGANKSILVDTKKTPLIDSLLQPTALYVELVQSLLKHTIPIKGMAHITGGGLPENLPRCLPNGLNAFIEPGSWDIPEIFFWLKKAGHIPEDDWWNTFNLGIGFCLVVSTDQVEAALEICTEIGWDAWTIGRVQEPTVPGQQRLIGLPE
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOS3_MOUSE
Sequence: MAEVLSAGPESVAGCRARAVHKVLNQVVLPGEELVLPDHEDVDGLGGAGEQPLRLNAGARPRLRVVCGPGLRRCGDRLLVTKCGRLRHKEPSGGGGGVYWVDSQQKRYVPVKGDHVIGIVIAKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHMTTEQRKQIFARLAES
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.  EXOSC3 as peripheral part of the Exo-9 complex stabilizes the hexameric ring of RNase PH-domain subunits through contacts with EXOSC9 and EXOSC5 (By similarity).
What are the official names of this protein?
Exosome complex component RRP40, Exosome component 3, Ribosomal RNA-processing protein 40.
What is the protein family that this protein belongs to?
Belongs to the RRP40 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Nucleus.
Protein: PTH_RHOPS
Sequence: MRLFVGLGNPGSKYQDNRHNIGFMVIDEIARRHGFSPWRRRFQGETADGSLDGERITLLKPLTYMNESGRAVQEAVSFYKIGHGEVAVFHDEIELPPAKLRVKVGGGIAGHNGLRSISAHIGNDYLRVRLGVGHPGVKELVHGHVLGDFAKSERPWVAALAEAVADNAGLIAKGREATFANKVHLALQARGFLDDDNKKSGADKAAK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_BIFLO
Sequence: MRQSANLVRKHIVVTGLVQGVGFRYFTVTQARRLGVQGWVRNCRDGSVELEAQGSSDAVQALVEQLAIGPRWSEVSHVAVHDMPIIDETARAFGVRQ
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: TAF7_YEAST
Sequence: MAVIRIKKPRGPGEKDQPLEGEPKLKRIRIKTKVTDEDIKPKPKLKINLKKKKESADGKEKKNSLKLKLNLKKNEEPVKKIHKAPKLRLKPIRIPGEAYDSEASDIEDDPLIESGVILRILPDIQLEFVKNSLESGDYSGISIKWKNERHAVVTINDVMYGAILVDLPTVIEVNKSVDRKNLLKTFDVSQMLLCIRPIQEEEEVYALEAPDTEDLVVKHFEGIEDEIWENKETFLKGYNGAPLSDMEAKHLKEIALKGYDYKHGISPPLYNVRNRRFRRKMDPNEIDYVEKVVDMLLKQDKQAEEVSYDLVDKSELQARQERVSSWENFKEEPGEPLSRPALKKEEIHTIASAVGKQGAEEEGEEGMEEEEEEDLDLGAAFESEEEGSGAEGDKEQQQEEVGDEVDQDTGGEDDDDDDDGDIEAAGGESESDDEKDENRQHTELLADELNELETTLAHTKHKLSKATNPLLKSRFIDSIKKLEKEAELKRKQLQQTEDSVQKQHQHRSDAETANNVEEEEEEEEEEEEEDEVDEDEEDDEENDEDEDNVHEREHIQENKVVRELDEAPAEETLDQNDLDMMMLFGAEGDE
What is the function of this protein?
Functions as a component of the DNA-binding general transcription factor complex TFIID.  Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation.  TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.  TAF7 is responsible for the recruitment of BDF1 to TATA element containing promoters.
What are the official names of this protein?
Transcription initiation factor TFIID subunit 7, TAFII-67, TBP-associated factor 67 kDa, TBP-associated factor 7.
What is the protein family that this protein belongs to?
Belongs to the TAF7 family.
Protein: MA653_ARATH
Sequence: MASVQKDPILQVETTCGSLLFELQIIWDEVGETETDRDQMLLELERECLEVYRRKVDQANRCRAQLRQAIADAEAQLAAICSAMGERPVHIRQSDQSVGSLKQELGRILPELEEMQKRKVERRNQFIVVMEQIDSITNDIKGQGELVHSEPLIDETNLSMRKLEELHCQLQVLQKEKIDRVETIRKHLCTLYSHCSVLGMDFNEVVGQVNPTLSDPEGPRSLSDHTIEKLGAAVQKLMEVKIQRMQRLQDLATTMLELWNLMDTPIEEQQEYQHITCNIAASEHEITEANSLSEDFIKYVEAEVVRLDEVKASKMKELVLKKRSELEEICRKTHLLPVSDSAIDQTIVAIESGIVDATMVLEHLEQHISKIKEEALSRKEILERVEKWLSACDEESWLEEYNRDDNRYNAGRGAHLTLKRAEKARNLVTKLPGMVEALASKTIVWEQENGIEFLYDGIRLLSMLEEYNILRQEREEEHRRQRDQKKLQGQLIAEQEALYGSKPSPSKPLGGKKAPRMSTGGASNRRLSLGAAMHQTPKPNKKADHRHNDGALSNGRRGLDIAGLPSRKQSMNPSEMLQSPLVRKPFSPISTTVVASKANIATTTTQQLPKNNAVNEISSFATPIKNNNILRNLEEEKMMTMMMQTPKNVAAMIPIPSTPATVSVPMHTAPTPFTNNARLMSEKPEVVEYSFEERRLAFMLQSECRLV
What is the function of this protein?
Microtubule-associated protein that plays a critical role in organizing the mitotic microtubule array during both early and late mitosis in all plant organs.  Essential for the cytokinesis, especially in roots, by maintaining the integrity of the overlapped microtubules in the phragmoplast.  Required during root morphogenesis.  Needed for giant cell development during root knot nematode infection, where cytokinesis is initiated but not completed.
What are the official names of this protein?
65-kDa microtubule-associated protein 3, AtMAP65-3, Protein PLEIADE.
What is the protein family that this protein belongs to?
Belongs to the MAP65/ASE1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, phragmoplast. Note=Locates only to the mitotic MT arrays. Present in MT cortical arrays just before mitosis. Associates to MT in preprophase band, during anaphase, and in phragmoplast, including midzone. Distributed diffusely through the cytoplasm during metaphase only. At the end of cytokinesis, present only at the cell periphery, forming a ring around the newly formed cell plate. During root knot nematode infection, targeted to the giant cell mini cell plate.