PharMolix/UniProtQA huggingface dataset:
Protein: PPOC_ASPFU
Sequence: MLRRFSSTFKKKGDRESKQNGTASSSSAAVANTNNNDNKRHSKISAARKSSSDDDRNEKKGNSVSPFEKYASVLHASRSPIPNQTGDGAYLEHEHTTSLLQDARHLGFKDFKTLKEVIESKLPGGQLIDDKTMLMERIIQLVSRLPHNSKHREELTNAFLTELWDSLPHPPLSYMGNDYAYRSADGSNNNPTLPRLGAANTLYARTIPPLIIQPGGLPDPGLVFDTLFARQTFKPHPNKVSSVFFYWASLIIHDIFQTDYKNPNMNKTSGYLDLSILYGDVQEEQNLIRTFKDGKLKPDSFSEPRLQAFPATCCVLMVMLNRFHNYAVEQLAAINENGRFTKPADNLSEEEAKKAWAKYDEDLFQTGRLITCGLYINITLYDYLRTIVNLNRTNSTWCLDPRAQMEGSHTAPSGLGNQCSVEFNLAYRWHSATSATDEKWTEDVYERLMGKPASEVSMTELLMGLGKYQAELPKDPSKRTFADLERQADGRFKDEDLVNLLVNAVEDVAGSFGARNVPKVLKNVEILGIIQSRKWNVGSLNEFRKFFGLKPYETFEEINSDPDVAESLRSLYDHPDFVELYPGIVAEEAKQPMVPGVGIAPTYTISRAVLSDAVALVRGDRFYTIDYNPRNLTNWGYSEVRYDLSINQGCIFYKLATRAFPNWFKPDSIYAHYPMTIPSENRKIMKDLGREIHYSWDRPQYTPPRVDLVSYSNAKLVAEQQNQFRAAWGDTVEFVFGKASKEFKLYQDSAFIQKHADVMSKLLNKEEWHRSVKEFYEDITAKLLEDKTRRFGGINQVDITNDVGNLTPVIFAANVFSLPLKSKENPRGIYTEHEMFKVLAALYNCLYFDIDKTKSYPLHHASQAVGEPLGKALEANVKALGGSSLLSGIFRSFRENKNALKEYGVHLTKQLLENGLGAHEIAWAQFLPTVIAMVPAQAQAFTQIVDFYLSKEGSKHLPAIQRLAKQDTKKSDEQLLHYCLEAVRLNDMSGLYRQSETTLAVTDEAVEVTIQPGDKVFVSFAKANRDASVFPDPAEVRLDRPMNSYINPTLGPHGFLSKETSHIALTAMLRAVGRLNNLRVAPGVQGQLKKIPQPGGYSAYLREDHGSYSIFPTTFRVQYDA
What is the function of this protein?
Responsible for the synthesis of various fatty acid-derived oxylipins.  Oxidizes linoleic acid primarily to 10R-hydroperoxy-8,12-octadecadienoic acid (10R-HPODE) and, to a lesser extent, 8R-hydroperoxylinoleic acid (8R-HPODE).  Also synthesizes 10-hydroxy-octadeca-8,12-dienoic acid (10-HODE) from linoleic acid and primarily 8R-hydroxy-octadeca-9-monoenoic acid (8-HOME, also known as psiB beta) from oleic acid.  8-HOME forms part of psi factor, a mixture of oxylipins that regulates the balance between sexual and asexual spore production.  Displays epoxyalcohol synthase activity.  Plays a role in the synthesis of prostaglandins which may be required for pathogenicity.
What are the official names of this protein?
Linoleate 10R-lipoxygenase, Cyclooxygenase-like fatty acid oxygenase, Fatty acid oxygenase ppoC, Linoleate 10R-dioxygenase, 10R-DOX, Psi-producing oxygenase C, AfPpoC.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family.
Protein: UBC12_DICDI
Sequence: MFRLKELQKKQQQQQQQQQQAAAPATNGTDAVTTEPTDVKRQNSNDLKEIRKQKSKDSYFSLKTKQSSESGSKRANPAELRAQKDIDEMEVPTGCAVSFKDTNDILNFNLSITPTDGLYQSATFQFTINIPSTYPYDPPKVHCDTLVYHPNIDLEGHVCLNILRQDWMPVLNIGTVIFGLMTLFLEPNPDDPLNKDAAQLMIDNKKTFEANVRQSLRGGYISNRQFPKLL
What is the function of this protein?
Accepts the ubiquitin-like protein nedd8 from the uba3-nae1 E1 complex and catalyzes its covalent attachment to other proteins.
What are the official names of this protein?
NEDD8-conjugating enzyme Ubc12, NEDD8 carrier protein, Ubiquitin-conjugating enzyme E2M.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.
Protein: CLPB_XYLFA
Sequence: MRMDKLTSRFQNALADAQSLAVGRDHTIIEPVHVFSALLDQQGGSTRPLLMQAGVNVPLLRERLTEILEALPKVSGQTVNVSPSNELSRLFHRTDKLAQQHGDQFMASEWFVLAVVDDSGGLGQALRAAGAEKKKIEAAIDKLRGGETVQTENAEEQRQALEKYTIDLTARAESGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLRSKRLLSLDLGALIAGAKFRGEFEERLKGVLNDLAKNEGRVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQKVFVGEPTVEDTIAILRGLKEKYALHHGVEITDPAIVAAATLSNRYITDRQLPDKAIDLMDEAASRIRMEIDSKPEELDRLERRLIQLKIQREMLKKEKDEASKQRLADLERDIEVLDREFSDLEEVWRSEKAALQGATKIKESIEQAKLDLEAAQRRQDYAKMSEIQYGVLPALEKQLVAASQAEQHDFTLVQEKVTAEEIAEVVSRWTGIPVSKMLEGERDKLLRMEADLGRRVVGQEEAIKVVSDAVRRSRTGLSDPNRPSGSFLFLGPTGVGKTELCKALAEFLFDSQDAMVRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTELVRRRPYSLILLDEVEKAHSDVFNILLQVLDDGRLTDGQGRTVDFRNTVIVMTSNLGSHQIQELSGDDSPEVYTQMKAAVMEVVQAHFRPEFINRLDDIVVFHPLDKAQIKQIARIQLQGLEKRLAESELKLDLDDRALELLGNVGFDPVYGARPLKRAIQSQLENPLAQQILAEAFVSGDTVQVGVDGGKLVFAKV
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_POLNA
Sequence: MAYLLALDQGTSSSRSIVFDEEGRVVALAQRELPQIYPRPGWVEHDPMEIWRGQLATARQALASVGLAAWDIRAMGITNQRETTVLWNRRTGQPVHHAIVWQDRRAESTCAQLREQGHEALIQAKTGLLIDAYFSGTKLKWLLDNVAGVRAQAERGELAFGTIDSWLIWQLTGGTVHATDVSNASRTMLFNVRTNQWDAELLDLLGIPASLMPEVKPSSAHYGEVRPELLGHAIPIGGVAGDQQSALFGQACFRAGMAKNTYGTGCFLLMHTGAQFQASKNGLLTTSAAQTTAQTEFALEGSVFVGGAVVQWLRDGLHAIQGSAEVEALAQSVPDSGGVMMVPAFTGLGAPYWKPEARGTITGLTRGTTMAHIARAALESIAYQSAALLLAMSRDAVAAGAAPLAELRVDGGASSNDLLMQFQADLLGIPVIRPAVTETTALGAAWLAGLSSGVYGSTDELSSLWRAERTFLPTLSTGRAAELMAQWEHAVRQTVLA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RLMH_PASMU
Sequence: MKIQLIAVGTKMPNWVTMGFEEYQRRFPKEMPFELIEIPAGKRGKNADIKRILEQEGKAMLAACGKSRIVTLDIPGKPWTTEQLATQLEVWKNDGRDLSLLIGGPEGLSAECKAAAEQSWSLSPLTLPHPLVRVVVAESLYRAWSVTMNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_THISH
Sequence: MSMTDPVADMLTRIRNGQRASKNEVSMPASKLKESIAKVLKDEGYIADYGVDAADGKPVLNIKLKYFQGKPVIETIKRVSRPGLRIYRSKDELPKVIGGLGVAIVSTSNGVMTDRAARALGQGGEVLCIVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: HRH4_HUMAN
Sequence: MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS
What is the function of this protein?
The H4 subclass of histamine receptors could mediate the histamine signals in peripheral tissues.  Displays a significant level of constitutive activity (spontaneous activity in the absence of agonist).
What are the official names of this protein?
Histamine H4 receptor, H4R, HH4R, AXOR35, G-protein coupled receptor 105, GPRv53, Pfi-013, SP9144.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ANGT1_BOTJA
Sequence: DRVYVHPFYL
What are the official names of this protein?
Angiotensin-like peptide 1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
Protein: MNTP_CROS8
Sequence: MNLSATLLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGVIEAITPLVGWLLGLLATQFVLTWNHWIAFVLLVFLGGRMIIEGVRGCEEASEKIRRHSFWLLVTTAFATSLDAMAVGVGLAFLQVDIIKTALAIGCATLIMSTLGMMVGRFIGPLLGKRAEILGGVVLIGIGCQILWSHFAG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KIF2C_HUMAN
Sequence: MAMDSSLQARLFPGLAIKIQRSNGLIHSANVRTVNLEKSCVSVEWAEGGATKGKEIDFDDVAAINPELLQLLPLHPKDNLPLQENVTIQKQKRRSVNSKIPAPKESLRSRSTRMSTVSELRITAQENDMEVELPAAANSRKQFSVPPAPTRPSCPAVAEIPLRMVSEEMEEQVHSIRGSSSANPVNSVRRKSCLVKEVEKMKNKREEKKAQNSEMRMKRAQEYDSSFPNWEFARMIKEFRATLECHPLTMTDPIEEHRICVCVRKRPLNKQELAKKEIDVISIPSKCLLLVHEPKLKVDLTKYLENQAFCFDFAFDETASNEVVYRFTARPLVQTIFEGGKATCFAYGQTGSGKTHTMGGDLSGKAQNASKGIYAMASRDVFLLKNQPCYRKLGLEVYVTFFEIYNGKLFDLLNKKAKLRVLEDGKQQVQVVGLQEHLVNSADDVIKMIDMGSACRTSGQTFANSNSSRSHACFQIILRAKGRMHGKFSLVDLAGNERGADTSSADRQTRMEGAEINKSLLALKECIRALGQNKAHTPFRESKLTQVLRDSFIGENSRTCMIATISPGISSCEYTLNTLRYADRVKELSPHSGPSGEQLIQMETEEMEACSNGALIPGNLSKEEEELSSQMSSFNEAMTQIRELEEKAMEELKEIIQQGPDWLELSEMTEQPDYDLETFVNKAESALAQQAKHFSALRDVIKALRLAMQLEEQASRQISSKKRPQ
What is the function of this protein?
In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309).  Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894).  Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108).
What are the official names of this protein?
Kinesin-like protein KIF2C, Kinesin-like protein 6, Mitotic centromere-associated kinesin, MCAK.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Associates with the microtubule network at the growing distal tip (the plus-end) of microtubules, probably through interaction with MTUS2/TIP150 and MAPRE1 (By similarity). Association with microtubule plus ends is also mediated by interaction with KIF18B. Centromeric localization requires the presence of BUB1 and SGO2.
Protein: LHX2_HUMAN
Sequence: MLFHSLSGPEVHGVIDEMDRRAKSEAPAISSAIDRGDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKMLTTGDHFGMKDSLVYCRLHFEALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGANPLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENTGVDKSTDAALQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVPGNLEGHEPHSPSQTTLTNLF
What is the function of this protein?
Acts as a transcriptional activator.  Stimulates the promoter of the alpha-glycoprotein gene.  Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).
What are the official names of this protein?
LIM/homeobox protein Lhx2, Homeobox protein LH-2, LIM homeobox protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SNTG2_MOUSE
Sequence: MSAEGSQSLAAPRGRPSHLLVPARTKTALALLYDEGLENAYDVRLKLTKEVLTIQKQDVVCIGGAPPGANHRTVTLRRQPVGGLGLSIKGGAEHGVPVVISKIFKDQAADQTEMLFIGDAVLQVNGINVENATHEEVVHLLRNAGDDVTITVEYLREAPSFLKLPLGSPGPSSDHSSRASSPLFDSGLHLNGHCSHTAPSSPSSPIANEPKYEKRWLDTLSVPLSMARISRYKAGTEKLRSSALEVLALDGASTGVLQFSTAQDCADWLRSISTNISDLTLQHMKMANKCCSPCDQVVHMGWVNERLQGADNSQNFRPKFLALRGSSFYIFGAPPVSTLDWGRAERAYNLCEVLFKVHKFWLSDNYWLQANLYLGLQDFDCEDPRSYCFSVLANHGKSHIFSVELGSELAVWEKAFQRATFMEVQRTGSKTYLCSWQGETLCFTVDFALGFTCFDGKTKNVLWRFKFSQLKGSSDDGKTRVKLLFQNLDTKQIETKELEFQDLTAVLHCIHSFIAAKVASLDPVFMDSQSMARRYLCSS
What is the function of this protein?
Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins.  May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (By similarity).
What are the official names of this protein?
Gamma-2-syntrophin, G2SYN, Syntrophin-5, SYN5.
What is the protein family that this protein belongs to?
Belongs to the syntrophin family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane.
Protein: CUTC_XANCP
Sequence: MGLEVAADSVGSALAAQDGGAIRVELCGGLDGGGLTPSFGTLAVVRERLQIPLYVLIRPRVGDFVFDAAEVEVMRRDVEQCVRLGCDGVVLGALDPQGQVDLPAMRALIEAAGTLGVTFHRAIDVSADPARVLEDAITLGCERVLTSGARASALEGVETIAALVRQAGERISIMPGAGVSAANVQALRAGTGAREFHASARGPVAAQVHAPHPYITDLGGDYQRTDVARVRSIVQLLQTA
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR8_STAEQ
Sequence: MIERYSRDEMSSIWTDQNRYEAWLEVEILACEAWSELGYIPKEDVKKIRENAKVNVERAKEIEQETRHDVVAFTRQVSETLGDERKWVHYGLTSTDVVDTALSYVIKQANEILEKDLERFIDVLAAKAKKYQYTLMMGRTHGVHAEPTTFGVKMALWYTEMKRNLKRFKEVRKEIEVGKMSGAVGTFANIPPEIEAYVCEHLGIDTAAVSTQTLQRDRHAYYIATLALIATSMEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSENITGISRVIRGYITTAYENIPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRLTVYEDNMRNNIDKTYGLIFSQRVLLALINKGMVREEAYDKVQPKAMESWETKTPFRELIEQDSSITDVLSSEELDDCFDPKHHLNQVDTIFARAGLS
What is the function of this protein?
Catalyzes two reactions in de novo purine nucleotide biosynthesis.  Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.
What are the official names of this protein?
Adenylosuccinate lyase, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: YFBU_SHIF8
Sequence: MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQMRELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEARYLGYVRFMVNVEGRYTHFDAGTHGFYAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: XPT_STRP7
Sequence: MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQDGRDLLEKAGYPVLSLARLDRFENGQVVFKEADL
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_RICCK
Sequence: MKKNPKISLIGSGNIGGTLAHLISIKELGDIVLFDVAEGVPQGKALDLMQAGTMLGSDIKIKGSNNYKDIEGSDAIIITAGLPRKPGMSRDDLISVNTKIMKDVAQNIKKYAPSAFVIVITNPLDVMVYVILKESGLPHNKVIGMAGVLDSSRFNLFLAEEFKVSVNSVNSIVLGGHGEAMVPLARYSTVSGIPIPDLIKMGLSSNENIEKIIDRTRNGGGEIVALLKTGSAYYAPATSAIEMLESYLKDKRQILTCAAYLQGEYGIHDLYVGVPIIIGTEGVLNVIELQLTKEEKALFDKSVEGVRKLIEMVK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: AROB_XANOM
Sequence: MTLPRSSRSVAVDGAQPYTITIAPGLLADGARLARHVRGRHALLLSDSQVAPHYAAGVRAALLSARPDLQIGELVIAAGEASKTLDTFGSAITALAELGATRDACVFALGGGVVGDLAGFAAACWMRGVDCVQLPTSLLAMVDSSVGGKTAVDIPQGKNLVGAFHPPRAVLADTDTLRTLPARELRAGLAEVIKYGAIRDPLFFQWLHAERHALLDSDPAALAQAIARSCEHKAEIVARDPLEKGERALLNLGHTFGHAIETEQGYGAPGNDNLNHGEAVAVGMVLAARLSATLGMSNAQDTEALRALLHDFELPTDIPPGLPPEALLARMRLDKKNIAGRLRLVLWRGIGKAEVVPDVEEAAVLKILAG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2061_AROAE
Sequence: MQIVLISGLSGSGKSIALKVLEDVGYYAVDNLPATLLPELVAELSDTGHERVAIAVDVRSGASLLALPQQVEHLHALASDLRLIFLDARDDTLIARFSETRRRHPLASEDVSLAEAIQSERDALASIAELGHRIDTSELHANTLRAWIKDFLAIEATEGLTLMFQSFGFKYGIPLDADLVFDVRCLPNPHYDLRLRPFTGKDQPVIEFLDSFPEVGRMCEDIRRFVATWLPSYARDNRSYLTVAIGCTGGQHRSVYIAEWLGRHFSDTLRVLVRHRSAARRIVDHGADMADK
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein AZOSEA20610.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: PTH_NOSP7
Sequence: MTEAATQPALVIPQLIVGLGNPESKYDQTRHNIGFAAVEALSRSWRISLAENRKFQGEYGEGMAPGGGKIRLLKPLTYMNRSGQSIQAVTSWYKLPPESVLIIYDDMDLPLGKTRLRLSGSAGGHNGMKSAIAHLSTQNFPRLRIGIGKPKGAADNDDSNTVSHVLGRFSSAENQQMSLVLQFVVECIELSLKQGVEKAMNVCNSRTINNSES
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RU1C2_PUCGT
Sequence: MGKYYCDYCDVFLVSESPSVRKAHNSGRNHLTNVRDYYSSLGHDKAQSYIDEITRMFETGGGNSTSNRGPGGNPPGSQPGPPNAGMSGPMRPPFSNSTAGPNMPPLPPAMLALMNGQNGMSSPGSGPPPMRFAGPPIPNNMPPGMMQPPHVNGYSSGPLPPQPQPASGGQGAPPLTARMNPDRARQLG
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C-2, U1 snRNP C-2, U1-C-2, U1C-2.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURC_STREM
Sequence: MSKTYHFIGIKGAGMSALALLLHQMGHKVQGSDVEKYYFTQRGLEQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQFTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHFMPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPAPIYYYGFEDTNDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIANLFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYPNKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAARVERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_METST
Sequence: MIITIGGLAGTGTSTTAKTLSQEINIPFISAGDVFRQMAVENNMTLLEFSEFAEGNDNIDKALDKRQAEIANNSENLIVEGRISAFFVNADYRIWLKAPDNVRAERISYREDKSLDTVKQEIAERTASERKRYMEIHDIDIDNLDIYDLIINTDTFNIESTVNIIKKCIENKK
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDI_MYCBP
Sequence: MTRSYRPAPPIERVVLLNDRGDATGVADKATVHTGDTPLHLAFSSYVFDLHDQLLITRRAATKRTWPAVWTNSCCGHPLPGESLPGAIRRRLAAELGLTPDRVDLILPGFRYRAAMADGTVENEICPVYRVQVDQQPRPNSDEVDAIRWLSWEQFVRDVTAGVIAPVSPWCRSQLG
What is the function of this protein?
Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate Delta-isomerase, IPP isomerase, IPP:DMAPP isomerase, Isopentenyl pyrophosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_AGRRK
Sequence: MGVAQSNTTLVAPQPKGIIDPATGKPVGSNDPFFGEINNELADKGFLVTSTDELINWARTGSLMWMTFGLACCAVEMMQVSMPRYDVERFGFAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPIDIYIPGCPPTAEALLYGVLLLQKKIRRTGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CDS3_CONLT
Sequence: MPKLEMMLLVLLILPLCYIDAVGPLPPWNMEDEIIEHWQKLHCYEISDLTPWILCSPEPLCGGKGCCAQEVCDCSGPACTCPPCL
What is the function of this protein?
Probable neurotoxin.
What are the official names of this protein?
Conotoxin Lt28.3, Conotoxin Lt15.6.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1724_ACIBC
Sequence: MHCDIYRSSKKDEMYIYIARPNYPDETEQADPFEKVPEAVLQAFGRATFVMHLELAPTRKLARVNVLHVLDSLQTKGFFIQMPPEGLINPNAVEPEGLRGA
What are the official names of this protein?
YcgL domain-containing protein ACICU_01724.
Protein: RECR_GEOSL
Sequence: MVHFSDSLSRLLAELQKLPGVGEKTALRLAFHLLKSPDNAAALADSLRDVMSRVRFCSVCFGITEDDPCRFCSDARDDGAICVVEEPQDLLAVERTRAFRGRYHVLQGALSPLNGVTPDRLRVAELMKRLEGGGVREVVIATNFTVEGEATALYLARMIKPLGVRVTRLAHGIPLGSDLEFVDAATVQRALEGRSEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: NADE_SHIFL
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETRNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLTALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNLPEQVARTIENWYLKTEHKRRPPINVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.