PharMolix/UniProtQA huggingface dataset:
Protein: ATPE_CHLRE
Sequence: MSLQISILTPERPFWNGQADEIILPTETGEMGVLKNHAPIITGLNVGAMLIRGGQASGSKDEWNSYAIMGGFALVKQNQVTILANEAVSAENINPEEAKDAFETAKANLEKAEGVKEKVEANFAYKRAKARYQVVKVLKKI
What is the function of this protein?
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient.  F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: LMBD1_AJECN
Sequence: MALLQSSLIWVVYAIVFFLLVAVSSIFIYIYQTPSERSTYVTTVCIFTLTALLATVLLLPVDVALVSSTTSSREGRRKSWATQDEVDKITFSLAVAYYFLYSLDAVLCLLVVPFTYFWYEEYDEVASEDGSQTFRKRFWGAFKYTVAFILLTVILFLVGFFVPIGRRKDKPNLDLDYFRRLLTENHGERALTFALGLLITIGILVYVLYTSTGLALLPVTIIKSAPAISSPTLSANTASRLEENIERQRQLEGRCGGNPDRLPSKQRRELDSLVRQARTLRRRQRLAEEARRPSGSWLLNAWFKLSAVFRPLKLLSGLLLLAIAMLVWVSMLLTSIDKAMNSICKQNCGYILGKTNILNPINWVFVHSSKVFPVDYILFVFLVLVFFCSSVVGIATTGIRFLWVRIFQLRKGHTSPQALLITTVMLTLITLALNYSISMVVAPQYATYGPQTFCDHPPKHPGEQPDCTGLEPLIKPCSELSENPTAKEICTPTVVSTFLNRITLNFPFFGIVDFWAQFFFLGLSLLVFLVTIFRTPKLDEQQFDEDAEAAEEEGLLASTGRRFGATWEDITGRASRSPQVSGSAGRGTRE
What is the function of this protein?
Probable lysosomal cobalamin transporter.  Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).
What are the official names of this protein?
Probable lysosomal cobalamin transporter.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: TM39A_DANRE
Sequence: MPGGRRGPSRQQLSRSALPSLQTLVGGGLSNGAGLRCRSSSAVGLSAPPLTALITPEPVRHSRIPDLPLDSNLLFETLLLLYLLVALLVQYINIYRTVWWSSYSQPTASTSLNFHLMDAHLAVFIAVMLSRRLVWTLLSEVCVACPASPLCYVLLLVVRVCVLTLCGWVLCWTLLNLFRSHSVLKLLFLGYPFGVYVPLCCLHQDGSPAADCGFADADGADGALLQPRDFLTLLRENLRQQLSGTHTHTHTHTCPPSPELIRSEVQQLKTDFNRRIKEVLFNSLLSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLMSHLLPPHYCDLLHRCAAHLGRWQRLEPGSCSNTPQHTWSDSTIWPQGVLVRHSRCLYKAVGPYNVALPSDVSHARFYFLFHKPLRLLNVLIGIECSVVVYQLYSLLRSERWNHTLSLGLILVCNYYVLFKLLRDRLVLGKAYSHPLGSAGLGMKRD
What is the function of this protein?
Regulates autophagy by controlling the spatial distribution and levels of the intracellular phosphatidylinositol 4-phosphate (PtdIns(4)P) pools (By similarity).  Modulates (PtdIns(4)P) levels by regulating the ER-to-Golgi trafficking of the phosphatidylinositide phosphatase SACM1L (By similarity).
What are the official names of this protein?
Transmembrane protein 39A.
What is the protein family that this protein belongs to?
Belongs to the TMEM39 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y4AS_SINFN
Sequence: MANTGAAKRIIEPLDPNRHDRAAFFCGIIQVDNFFKKTANKLSKADNLRVYVMTEDDGTTVIGFYAINSHSISYADLPERFSRTRPGHGSIPAAYISMIGRDQRYRGGGYGGDLLTDCLQRIAGIADQIGIAVVLLDVLVCGDEEKTSRRVALYSEYGFQPLPSMPLRMFLPIATIRSLMG
What are the official names of this protein?
Uncharacterized protein y4aS.
Protein: YIDD_ECOHS
Sequence: MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEALRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RPPH_ERWT9
Sequence: MIDDDGYRPNVGIVICNRQGQVLWARRFGQHSWQFPQGGINPGETAEQAMYRELFEEVGLNRKDVRILAATRNWLRYKLPKRLVRWDTKPVCIGQKQKWYLLQLMCNDADINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMPLQESTTQRNTPGYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: KI26L_CAEEL
Sequence: MEACSSKTSLLLHSPLRTIPKLRLCASISSEDVAHGRCSLTDQHLQIEGKNYSKTTFDHIFRTDATQDDMYTAFLSDTINSVFAGNDATVLAMGAKTNGKDERLYGNSVSRNGLVQMAITQLMNALDDNKDSEERIQVRMSAIMVSQNESSIVDLLSPFNPDPRHRVVKIVDDARTGVFIDNESEIRVETIDQALFYLNTAVDHRMIQDEHTHRTSHVFISLSLYSYKMGDKMQGGRRRLCFLDMGIGERNSTNGGMTMPALGSILLAMVQRNKHIPSRDSSVCQLIRCALSTSRFTTFVFSFGAKSDDNENIAHLACKIARTRAKSMVGHGRKSSGTMSTGTMESNSSSCGTTTITPGGTPRTQRRFELESGSELSAAETVIFLGPNSSRTASPASTTMPFTPTSIRPLHRTTRNHSGVEALSKPLSVETKSSPTHNCHDGCIHSIPPMLRGHTPFLSASLKLYDELCSPPSSSRASPAPPAAFGGKTSEKREDFGIMIAQPSIPLMKAKSKYNLDDGKMKQIMQWMETSEAPPILFSSPCYENSATSVEELRECVGILSHPLEDIIEQEEESMRTSTATTGGSKKDHPLRILSKQDLNVEPEIKDKQEENELELVMAASLSSMRSHDILAKLEAMRNAQNGNSVQNIGNSQSNTDMDVSEMDVYRRASHLEEYAMQRVREIEENKLKNKKKIKLGLNCCQQQSMISSGSTVVDWSQIERKKEKEREVHEEEMRKEMLRERRAKLKITELEIKRERNLIDKELDDKKGIANSIARQLQHFSLSPCRGGRTHRSVSTHRIDPPNASLPSTPTMSHKKVIGGSLAKLSASGASGSTGAPPSPALGYHQSLPRHSKLPTSVNGRRASAERERKSNKASRNSCSKERKISGSKEELQWRSPYAQMTSPKSYGGPGTSSSGRGSSAPGSDFETPVVSTTEKSANGTIPRSKRQSYSASSGYESANDYHIYSTTNKKPHILDKKRNEEKLSLVRQADEIRHRQWQLKKELEEAKRAIGQEDDAKMIANSSDQRLNGLSRTTMIDAMLQENRILEKRLVACRNHSMLVTTFI
What is the function of this protein?
Specifically required for CAN cell migration.
What are the official names of this protein?
Kinesin-like protein vab-8, Variable abnormal morphology protein 8.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF26 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CHIS_BACSU
Sequence: MKISMQKADFWKKAAISLLVFTMFFTLMMSETVFAAGLNKDQKRRAEQLTSIFENGTTEIQYGYVERLDDGRGYTCGRAGFTTATGDALEVVEVYTKAVPNNKLKKYLPELRRLAKEESDDTSNLKGFASAWKSLANDKEFRAAQDKVNDHLYYQPAMKRSDNAGLKTALARAVMYDTVIQHGDGDDPDSFYALIKRTNKKAGGSPKDGIDEKKWLNKFLDVRYDDLMNPANHDTRDEWRESVARVDVLRSIAKENNYNLNGPIHVRSNEYGNFVIK
What is the function of this protein?
Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan.
What are the official names of this protein?
Chitosanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 46 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPG_METNO
Sequence: MASLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQNAAENARPYAERMAAVLGNLATNLTPGAETPRLLAGTGADRVHLLVVCTAERGLCGAFNSSIARLARDHARRLVAEGKTVKIICVGKKGYDILRREFRDQIVELIELRGVRQLGFENAEAVTENLLNRFEAGEFDIATLFYSRFRSVIAQVPTAQQIIPAEISPASESAQTDAAYEYEPEEGEILAALLPKNLTVQILRALLENAASEQGARMSAMDSATRNAGEMIKKQTLVYNRTRQAMITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: F16PA_RHOCB
Sequence: MAIELEGLGLSPELADVMTRLARVGADLARTIARNGVETDLAAGVGTNAGGDGQKALDVMADDAFREALTGTAVAYYASEEQDEVVTLGKGTLALAIDPLDGSSNIDVNVSIGTIFSIFPATDDPNTSFLRKGSEQIAGGYIIYGPQCALVCSFGRGVHHWVLDLDSRSFKRLPDIKALPQDTSEYAINASNYRHWPSPIRAFIDDLVAGAEGPRGRNFNMRWIASLVAETHRILMRGGVFLYPGDERKGYARGRLRHVYECAPIAFLITQVGGGATDGCEDILSALPDKLHARTPFVFGCAAKVARVTAYHDLPGEETSALFNTRGLFRS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_CHLCV
Sequence: MLPLYLVHVLYPIGLIANLFFGSAFTIQWLLSEKRKTAYVPKAFWVLSSIGAVMMIAHGFIQSQFPMALLHGANLVIYFRNLNIASSYKLSLTTTLVILVLTLLVTTLPFALAAYYYPYMEWMASPNFFHLPLPPPNIYWHIVGCLGLFTFSSRFFIQWCYLEMNNHSTLPALFWQAGFVGGFLAFIYFIRTGDPVNILSYGCGLLPSLANLRIIYKKSRLPKFHSPSCFLSAGEPSGDTLGSDLLRNIKELNPNIHCFGVGGPLMRKEGLEPLIRMEEFQVSGFLEVFCAVFSLYKKYRKLYKAILKENPETVFCIDFPDFHFFLIRKLRKCGYRGKIIHYVCPSIWAWRPNRKKILEKHLDTLLLILPFEKEIFKDSPLKTIYLGHPLVKTIANFQDCNAWKQQLEISDQPSVALFPGSRPGDIFRNLQVQARAFRSSSLAKSHQLLVSSCNPKYDKKILELLDKEGCHNNKIVPSKFRYQLMRDCDCALAKCGTIVLEAALNQTPTIVTCLLRPFDTFLAKYIFKIFIPAYSLPNIITGSVIFPEFIGGKHDFSPEEVAAAIDILANPIGKEKQKYACQQLLKTMTENVITPKECLQAIYAQKNRFYLKNDFIKEFHPKSSRA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LpxB family.
Protein: RPOZ_STAAB
Sequence: MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHSFKPVGRALEEIADGKIRPVISSDYYGKE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL28_LEIXX
Sequence: MAAVCQVTGATPGFGHSISHSHRRTKRRFDPNIQKKTYYVPSLRRNVTLTLSAKGIKVIDARGIEAVVKDLLARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: SIS2_CANTR
Sequence: MPSDKDIKSPAQPKKEEEIPKSILTRISSPPPILNQPDANIIHHPQPQVPQSSLNIPGIKLSPQISTSLENREIVMAGGAYLKERMESPDSLNHKPTLLQPDKSESIPSIDYTLNPPKESQHHKSPSVHAHFYVEETLRPVRNRSRSGSNSNNNLTPITSPQHSEPSSILNKDAIKSQESLRATTNSISSAAASNQSTPRSIISGGGGGGGGANTATSSNSTTSNTALAAQGTTTTTTTTNSNSNTTTTKGEQNSNIDPRLPQDDGKFHVLIGVCGALSVGKVKLIVNKLLEIYTSDKISIQVILTKSSENFLLPETLNVLENVKKVRVWTDIDEWTTWKTRLDPVLHIELRRWADILLVCPLTANTLAKISLGICDNLLTNVIRAWNSSYPILLAPAMDSHSYSSSTTKRQLRLIADDMPWIEVLKPLEKVFGSYGDIGMGGMTDWNEIVNRIVMKLGGYPEDEDEDEADDSKDNIDESAIIDDDDDDDDDDDDDDDDDDDDDDDDDDDEEDPPQQQSTTDNSKDETTNL
What is the function of this protein?
May stimulate expression of certain genes that are periodically expressed during late G1.  Also modulates the expression of the ENA1 ATPase (By similarity).
What are the official names of this protein?
Protein SIS2, Halotolerance protein HAL3.
What is the protein family that this protein belongs to?
Belongs to the HFCD (homooligomeric flavin containing Cys decarboxylase) superfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GLMU_SHIDS
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDARPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYME_SALTI
Sequence: MTTVHSIADPCDPEVSPTNNRHLTVSYASRYPDYTRIPALTMKGQWLEAAGFATGTEVDVRVMNGCIVLTAQQPQPEESELMQSLRQACKLSARKQKQVQAFISVMAGSK
What is the function of this protein?
Involved in the degradation and recycling of damaged RNA.  It is itself a target for degradation by the ATP-dependent protease Lon.
What are the official names of this protein?
Endoribonuclease SymE.
What is the protein family that this protein belongs to?
Belongs to the SymE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACS1_ASHGO
Sequence: MVTSAGVGHAEYNNGADVQHADYAHLTSVGQVEQKPLGGRLGALAEYYKPNVASMEEYRAMHAQSITDPAAFYGERARTYVDWFRPFDAVFLPGPDGRPSFDNNAWFVNGQLNACYNLVDRHAARTPDKVAIIYEADEPGEGYSLTYRELLAQVCKVAQVLQYSMGVRKGDTVAVYMPMIPQALVTLLAISRIGAIHSVVFAGFSSNSLRDRINDARSEVVVTTDESKRGGKIIETKRIVDDAIKETPQLRKVLVYKRTCNPSVSYVADRDLDWDTEVKKYKSYCPCEPVDSEHPLFLLYTSGSTGAPKGVQHSTAGYLLQAYLSMLYSFDVHSDDIFFTAGDIGWITGHTYVVYGPLFSGCTTVVFEGTPAYPSYSRYWDIIDKYSVTQFYVAPTALRLLKRAGDSYVDGYSLRTLRSLGTVGEPIAAEVWEWYYTVIGKREIPVIDTYWQTESGAHLVTPLAGGSTPMKPGSASFPFFGIDLAILDPQTGEELLGPNVEGVLAVKQPWPSFTRTIWNNHDRYLDTYLNPYKGYYFAGDGAARDSQGFIWILGRVDDVVNVSGHRLSTAEVEAAIIQESMVAECAVVGFADELTGQAIAAFVVLKQKSSWNTASERELQEIKKHLILSVRRDIGPFAAPKLIVLVDDLPKTRSGKIMRRILRKILAGEADQLGDVSTLSNPGIVKHLIESVKF
What are the official names of this protein?
Acetyl-coenzyme A synthetase 1, Acetate--CoA ligase 1, Acyl-activating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Microsome. Endoplasmic reticulum.
Protein: NU5C_OENPA
Sequence: MEYTYQYSWIIPFIPLPVPILIGMGLLLFPTATKNHRRVWSFPSILLLSMVMLLSVYLSIQQINRSFIYQYVWSWTINNDFSLEFGHLIDPLASIMLILITTVGILVLFYSDNYMSHDQGYLRFFAYLSFFNTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPIAATACQKAFVTNRVGDFGLLLGILGLYWITGSFEFRDLFEIVNNLIDNNNQVHFLFVTLCSFLLFAGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFVITPYIMNLISLIGIITVLLGATLALAQKDIKRSLAYSTMSQLGYMMLALGMGSYRAALFHLITHAYSKALLFLGSGSIIHSMESIVGYSPDKSQNMVLMGGLKKHVPITKTAFLVGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIACSTAGFTAFYMFRVYLLTFDGHLNVHFQNYSGQKSSSVYSISLWGKQVPKRIQNPFCLLNLLTMNNNESTSFFWNNKCKLDGNVKKRIRPFITVTHFPNRKTFSYPHESDNTMLFSLFVLVLFTLFVAAIGIPFNQEGSDCDILSKLLNPSINLLHQNSNNFTDWYEFVTNASFSVSIALLGIFIATFLYKPIYSSLQNFNLLNSFYKRSANRVMWDKIQNWIYDWSYNRGYIDSFYTISLTGGIRGLAELSHFFDRRVIDGILNGFGLTSFFLGESLKYFGGGRISSYLLLYSIFIFIFLLMDSFFTNLPFFVLCQFLDSSFSMSISGFLLYENF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRB_HYPBU
Sequence: MGSGSGWKGRDVISILDFDRDSLEQLFEVADKFSSLLRERGRIPLLEGYIVALAFFEPSTRTRLSFETAAKRLGADTIGFTSEEAISIAKGETLADTIRMLDSYADMIVLRHRYEGAALYAAEIAEHPVINAGDGKQHHPTQAMLDLYTVRKLFGTIDGLTYGVLGDLRYGRAASSFILALTIYRPRMIYLISPPLLRVRPEVRMVLDERGMRYREVESLEEVLGELDVLYVTRIQRERFPDQREYEKVRGSYRVTLELLEQHARRELRILHPLPRVDEIAPEVDGTPYAAYFEQARNGVPVRMALLALIAGREV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TRMJ_KLEP7
Sequence: MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAQIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVAEGQHAPVALVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLAAQEQAQPAVEHEEAPYPLVDDLERFYDHLEQTLLATGFIRPNHPGQVMNKLRRLFTRARPESQELNILRGMLASIEQQNKGK
What is the function of this protein?
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
What are the official names of this protein?
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ, tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase, tRNA Cm32/Um32 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSB_BURMS
Sequence: MTSPLPFVAVVPARLASTRLPNKPLADLGGKPMVVRVAERAREAGAQQVLVASDAQRVLDAVREHGFDAVLTRADHPSGTDRLAEVAAKLGFDDDTIVVNVQGDEPLIDPQLVRDVASHLAAHPSCAIATAAHPIHEAHEVFNPNYVKVVLDAHGVALYFSRAPIPWSRDAYLPHWPNVAAMPAPTCPVYRHIGLYAYRARFLRTYPTLAQAPIEAAEQLEQLRAMWHGERIAVRVTEHAPEAGIDTPADLERVQALFRSRAK
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_SALTI
Sequence: MMTHWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTLHIEPRHDGEIHLLTPVTGVENEDNLIVRAARLLMKVASESGRLPAGSGADISIEKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSIDELATLGLTLGADVPVFVRGHAAFAEGVGEILTPVNPPEKWYLVAHPGVSIPTPVIFKDPQLPRNTPKRSIDTLLKCEFSNDCEVIARKRFREVDAALSWLLEYAPSRLTGTGACVFAEFDTESCARQVLEQAPEWLNAFVAKGVNLSPLHRELL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: ATPE_ZYGCR
Sequence: MTLNLRVMAPNRTVWTSEAQEIILSSNSGQIGILPNHAPLLTALDIGVMKVRIDSKWTAVALMGGFAQIENNQMTILVNEAEKASDIDPKEAQEAFDLAETSFNQAVGRKQTIEANLAFKRAKARLEAVNAKY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: GRPE_ALISL
Sequence: MNNEEKKVNEEIVVEDQIEAIGTEADVEWNESMEESQDAKIAELEAALLASQAQLKEQQDAVLRAKAEEQNVRRRAEGDIDKARKYALKKFAGELLPVIDNLERALESGDKENEAAKVLLEGVELTLQTFISTIEKFGLTVINPVGETFNPEHHQAIGMQASPDHESNTVMVVMQKGYSLNEQVIRPAMVMVAQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOX3A_XENLA
Sequence: MYSMLDTDIKSPVQQSNAPIGGPATPGGKGNASTLDQDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGADWKLLSDSDKRPFIDEAKRLRAVHMKDYPDYKYRPRRKTKTLLKKDKYSLPGNLLAPGVSPVASSVGVGQRIDTYAHMNGWTNGAYSLMQDQLGYSQHPAMNSPQMQQIQHRYDMSGLQYNPMMTSAQNAYMNAAASTYSMSPAYNQQSSTVMSLASMGSVVKSEPSSPPPAITSHTQRACLGDLRDMISMYLPPGGDASDPSLQNSRLHSVHQHYQSAAGPGVNGTVPLTHI
What is the function of this protein?
Transcription factor with sequence-specific DNA binding activity.  Binds to the consensus sequence 5'-[AT][AT]CAA[AT]G-3', showing a preference for 5'-AACAAT-3' and 5'-AACAAAG-3'.  Inhibits beta-catenin-mediated dorsal axis specification by binding to sites within the promoter of the beta-catenin-regulated gene nodal5.  Acts maternally as a transcriptional repressor of nodal5 and nodal6 to restrict their expression to the vegetal hemisphere of early embryos and thus establish germ layer formation.  Acts at multiple points to inhibit nodal signaling, repressing the expression of the other mesoderm-inducing nodal genes nodal, nodal2 and nodal4, and also acting downstream to induce expression of genes including trim33/ectodermin, ema and coco, whose products repress nodal signaling.
What are the official names of this protein?
Transcription factor Sox-3-A, xSox3, xSox-B1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Primarily cytoplasmic in early embryos. Nuclear localization becomes more pronounced as development proceeds.
Protein: CLPB_BRUME
Sequence: MNIEKYTERVRGFIQSAQTFALSSGNQQFTPEHILKVLIDDDEGLAASLVERAGGRVGDVRMGLQSALEKLPKVSGGNDQLYLSQPLAKVFSLAEELASKAGDSFVTVERLLTALAMEKSAKTSEILSAAGVTPTALNRVINDMRKGRTADSASAESNYDALKKYARDLTEDARAGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKQLMALDMGALIAGAKYRGEFEERLKAVLSEVQTAAGQIILFIDEMHTLVGAGKTDGAMDASNLLKPALARGELHCVGATTLEEYRKYVEKDAALARRFQPVFVDEPTVEDTISILRGLKEKYEQHHKVRVSDSALVAAAMLSNRYITDRFLPDKAIDLVDEAASRLRMQVDSKPEELDEIDRRIMQLKIEREALKVETDAASKDRLQRIEKELSDLEEESAELTAKWQAEKQKLGLAADLKRQLEEARNALAIAQRNGEFQKAGELAYGTIPQLEKQLADAESQENKGSLLEETVTPDHVAQVISRWTGIPVDRMLEGEREKLLRMEDEIGKRVVGQGEAVQAISKAVRRARAGLQDPNRPIGSFIFLGPTGVGKTELTKALASFLFQDDTAMVRIDMSEFMEKHSVSRLIGAPPGYVGYEEGGVLTEAVRRRPYQVILFDEIEKAHPDVFNVLLQVLDDGRLTDGQGHTVDFRNTVIIMTSNLGAEYLVNLGENDDVETVRDDVMGVVRASFRPEFLNRVDEIILFHRLRREDMGAIVDIQMQRLQYLLSDRKITLQLEDDAREWLANKGYDPAYGARPLKRVIQKEVQDPLAERILLGDILDGSLVKITAGSDRLNFRPISGAFSAAEPEREDEKA
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.