PharMolix/UniProtQA huggingface dataset:
Protein: SGMR1_HUMAN
Sequence: MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
What is the function of this protein?
Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane.  Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling.  Also regulates ion channels like the potassium channel and could modulate neurotransmitter release.  Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum.  Plays a role in several other cell functions including proliferation, survival and death.  Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration (PubMed:16472803, PubMed:9341151).  Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria.  Plays a role in protecting cells against oxidative stress-induced cell death via its interaction with RNF112 (By similarity).
What are the official names of this protein?
Sigma non-opioid intracellular receptor 1, Aging-associated gene 8 protein, SR31747-binding protein, SR-BP, Sigma 1-type opioid receptor, SIG-1R, Sigma1-receptor, Sigma1R, hSigmaR1.
What is the protein family that this protein belongs to?
Belongs to the ERG2 family.
What are the subcellular locations of this protein?
Nucleus inner membrane. Nucleus outer membrane. Nucleus envelope. Cytoplasmic vesicle. Endoplasmic reticulum membrane. Membrane; Single-pass membrane protein. Lipid droplet. Cell junction. Cell membrane. Cell projection, growth cone. Postsynaptic density membrane. Note=During interphase, detected at the inner and outer nuclear membrane and the endoplasmic reticulum. Detected on cytoplasmic vesicles during mitosis (PubMed:10406945). Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum. Accumulation at the endoplasmic reticulum is prominent in alpha-motor neurons of patients with amyotrophic lateral sclerosis (PubMed:23314020). Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand- binding. In motor neurons it is enriched at cholinergic postsynaptic densities (By similarity).
Protein: SH21A_MACMU
Sequence: MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIREDPDVCLKAP
What is the function of this protein?
Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7.  In SLAM signaling seems to cooperate with SH2D1B/EAT-2.  Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2.  However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1.  Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions.  Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation.  In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells (By similarity).  May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3 (By similarity).
What are the official names of this protein?
SH2 domain-containing protein 1A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM177_MOUSE
Sequence: MAGPLWRAAAFIQRHRTSLLVGSCAGLFGVQISFHLFPDPIVQWLYQYWPQGQPAPLSPHLWSLFQEVLKDIGVPSGHCYKPFTAFTFQPVSAGFPRLPAGAVVGIPAIFLGGPVTNIEHSVIIHGQRVDWQSPAGTRLRDALTMSHNAQKFALAKEVVYLESGVAALQTLPAPACLAGTWAISVGAKHALGLYGGPMSLRTAFNLVAIVVGYVAYTFSKDSLTLALEGWLDRRTASLSAAYVQGGVEFYEKILSGNLALRSLLGRQGEKLYTPSGNIVPRHWFRINHLPYTTRRDSLQQMWRATVSPGRF
What is the function of this protein?
Plays a role in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation and is required for the stabilization of COX20 and the newly synthesized MT-CO2/COX2 protein.
What are the official names of this protein?
Transmembrane protein 177.
What is the protein family that this protein belongs to?
Belongs to the TMEM177 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MRAY_STAHJ
Sequence: MLFILAVIALLITFILVPILIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLISIIITSIIAIFFVDNSNPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIAIAVVFFLLSDVFHLVEFSTNLNIPFTNISIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLDSPAIGAFCIIMIFALLGFLPYNLNPAKVFMGDTGSLALGGIFATISIMLNQELSLLLIGLVFVIETASVMLQVASYKLTKKRIFKMSPIHHHFELSGWGEWKVVTVFWTAGLISGLIGLWIGVH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DERL1_ARATH
Sequence: MSSPGEFYNSLPPITKAYGTLCFFTTVATQLGLVAPVHIALIPELVLKQFQIWRLITNLFFLGGFSINFGIRLLMIARYGVQLEKGPFERRTADFLWMMIFGSFTLLVLSVIPFFWTPFLGVSLVFMLLYLWSREFPNANISLYGLVTLKAFYLPWAMLALDVIFGSPIMPDLLGIIAGHLYYFLTVLHPLATGKNYLKTPKWVNKIVARWRIGAPVASVRQAGGVGAAGPGAGGGVGGGGAYSSARAPPESSNTAFRGRSYRLTD
What is the function of this protein?
May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins.
What are the official names of this protein?
Derlin-1, AtDerlin1-1.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ACCD_RHOPS
Sequence: MNWLTNVVRPKIRNILRRETPENLWIKCPDTGQLVFYKDVEQNQFVIPGSNYHMRMGALARLRSVFDNETWYDVALPEVTADPLKFRDERKYADRIKDARTKTGAHDAVKVGYGKLEGLGVVAAVQDFDFMGGSLGMAAGEAIIRGLELAVEKHAPFIMFAASGGARMQEGILSLMQMPRTTVAVQMLREAGLPYIVVLTNPTTGGVTASYAMLGDIQLAEPGALIGFAGARVIEQTIREKLPDGFQRAEYLRDHGMVDMVVHRHELRPTLARLCRILTKTPLPAVEEIAASDDAAQDAEAAAATEIVVTPPEAPSPTAPQA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FNDC8_MOUSE
Sequence: MATVFCKVGGGEEAVPKKEALNVINVIDQLPKPCPNPKFINRSMATKGLLLPSRRSLASFSEEENTDVMMHMPVEDSEYSSDDTSMSPIPSTLMNPIKMAVTQPNSSFFAGILEGELNKLSLASVVKNTEKDNLAICPRSSKSQIATRGLLDLDNPALDTDTSSTRSESSVVLDVPEVPFICEHTVGDSTAVISWTYAAGKQQVSFYQVLLQEATKPADKDTPKIKTRPWIFNKILGTTVKLMELKSNTSYCLTVRAANTAGVGKWCKPYKFATVSTDFNSFPETNPIQVTVQRKQPHRRTVSMTMEEMRRLEDLEYLYPY
What are the official names of this protein?
Fibronectin type III domain-containing protein 8.
Protein: DNLJ_CORJK
Sequence: MSTQSRWQELADQVRHHRQLYYYGEPEISDADFDALLQELKDLEQAHPEVVTGASPTEEVAPAPPTSSPFRNVDHREQMLSLDNVFDTEQLAGWLDRTPAKTYLTELKIDGASINLLYIDGQLELALTRGDGTTGEDITHNARTLDDIPDTLHGTDEFPVPELVEIRGEVFIDVEDFAAMNAQRQAEGLKMFANPRNAAAGAMRQKNSADTAKRPLKLICHGIGAREGFSPASQHDAYRAIAAWGLPVSPYTKQVHSAKEVQQQVEYWGNHRHDAAHEMDGLVVKVDSLEEQLELGHTSRAPRWAIAYKYPPEEAMTTLHNIRVGIGRTGRATPYAVMAPKYVAGSTVSMATLHNPTEAHRKGVLLGDTITIRKAGEVIPEVLGPVEDKRTGAERPFLFSTFCPECGTRLAPSKVGDADWRCPNTQYCPGQLHTRLTYLASRKAFDIDALGEKGAYDLIHSGVLADESELFDLRAEDLEKTSSYATKAGKLNKSGETLLEKLQSAKEADLWRVLVALSIRHVGPTAAKALAKHFESVEDIASASAEEMAGIDGVAETIAESISDWFTVDWHRRIVDRWAAAGVRMRREAGNVPGAADGVDSALLEGLTIVVTGSLEDFDRTAAKEAIEARGGKAAGSVSKKTDFLVAGEKAGSKLKKAEDLGVPVLDEAAFKELLENGAPSSGDDASTSADSVDD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RL32_STRZP
Sequence: MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSLKGYYKGRKIAKAASAE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: KAD_STRT2
Sequence: MNLLIMGLPGAGKGTQAAKIVEEFGVAHISTGDMFRAAMANQTEMGRLAKSFIDKGELVPDEVTNGIVKERLAESDIAEKGFLLDGYPRTIEQAHALDETLKALDIKLDGVINIEVNPESLVERLSGRFICRSCGSTYHKVFNPTKVEGTCDVCGGHEFFQREDDKPETVKRRLDVNIAQGEPIIAHYRELGLVSDIQGNQDIDDVFADVKKAIAAIK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATEA_XENLA
Sequence: MRQILVLLLFATLVYGLIRVPLKRQKSIRKTLKEKGKLSHIWTQQGIDMVQYTDSCSNDQAPSEPLINYMDVEYFGEISVGTPPQNFTVIFDTGSSNLWVPSVYCISQACAQHDRFQPQLSSTYESNGNNFSLQYGTGSLSGVIGIDAVTVEGILVQNQQFGESVSEPGSTFVDAEFDGILGLGYPSIAVGDCTPVFDNMIAQNLVELPMFSVYMSRNPNSAVGGELVFGGFDASRFSGQLNWVPVTNQGYWQIQLDNVQINGEVLFCSGGCQAIVDTGTSLITGPSSDIVQLQNIIGASAANGDYEVDCSVLNEMPTVTFTINGIGYQMTPQQYTLQDGGGVCSSGFQGLDIPPPAGPLWILGDVFIGQYYSVFDRGNNRVGLAPVVPYPPLKNGV
What is the function of this protein?
May have a role in immune function.  Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation (By similarity).
What are the official names of this protein?
Cathepsin E-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Endosome. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
Protein: TRUA_MYCCT
Sequence: MKTGILLTLCYDGSNYHGWINQTNSISTQTVLNKAIKKVIKTSEFKTIGASKTDANVHALDQKVLLIIYFTPILEKFINAINKALPEDIRILNAKFVDPNFNIREVDYKIYNYYINDHKFDIFTNRYEYFWKHSKIDILKLQEIFNLFIGEHEFKLFSGLKENEWDNYQTKRIIDDIKVLRINNKVVIQFKATGFIRYQIRIIIANCLNAYLNYKVNINTLTEMLQGIGKKTPFIIKAKGLVLQEIKFK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: PIGY_MOUSE
Sequence: MIRSLPTMTVLIPLVSLAGLLYSASVEEGFPEGCTSASSLCFYSLLLPVTVPVYVFFHLWTWMGLKLFRHN
What is the function of this protein?
Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis.  May act by regulating the catalytic subunit PIGA.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y, Phosphatidylinositol-glycan biosynthesis class Y protein, PIG-Y.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YQGF_HAEIE
Sequence: MGITALAFDFGTKSIGCAIGQSITGTAQALPAFKAQDGIPNWEAIEKCLKEWKPDVVIVGLPLNMDGTEQNLTLLARKFANRLQGRFGVNVHLQDERLTTTQARSEIFERGGFKALKKGKVDGISACLILESWFECTEY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_GEOSM
Sequence: MLMPKKVKYRKQMKGRMTGTPQRGVELAFGDFGLQATECGWLDSRQIEAARIAMTRYIKRGGKIWIRIFPDKPLTSKPAETRMGKGKGSPDSWVCVIKPGRILYEMEGVTEEVAREAFRLAAHKLPVASKFITRTEINEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PANB_PYRIL
Sequence: MRRKTVLDFAKGRGPYVWITAYDYPTAKAVDEAGVDGILVGDSLGMVLLGLPNTLGVTMEDMVRHTEAVARAKPRALVVADMPFMSYETGPEDALKNAARLIRAGADAVKLEGGAEYAHIVERLVKAGIPVMGHIGLTPQRVLTIGGFRMVGKTEEQRRKVLEDAKALRDAGAFSIVLEFVPASLAREVTQAVDIPTICIGSGPHCDGQILVLHDVIGLSERPPSFAKRYADVAAAIREAVSKYAEEVRKGLFPAREHYRE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_STRA3
Sequence: MKITKIEKKKRLYTLELDNTENLYITEDTIVHFMLSKGMIVNAEKLENIKKFAQLSYGKNLGLYYISFKQRTEKEVIKYLQQHDIDSKIIPQIIDNLKSENWINDKNYVQSFIQQNLNTGDKGPYVIKQKLLQKGIKSKIIESELQAINFQDLASKISQKLYKKYQNKLPLKALKDKLMQSLTTKGFDYQIAHTVIQNLEIEKDQELEEDLIYKELDKQYQKLSKKYDQYELKQRIINALMRKGYQYEDIKSALREYL
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_THET8
Sequence: MLKAFWSALQIPELRQRVLFTLLVLAAYRLGAFIPTPGVDLDKIQEFLRTAQGGVFGIINLFSGGNFERFSIFALGIMPYITAAIIMQILVTVVPALEKLSKEGEEGRRIINQYTRIGGIALGAFQGFFLATAFLGAEGGRFLLPGWSPGPFFWFVVVVTQVAGIALLLWMAERITEYGIGNGTSLIIFAGIVVEWLPQILRTIGLIRTGEVNLVAFLFFLAFIVLAFAGMAAVQQAERRIPVQYARKVVGRRVYGGQATYIPIKLNAAGVIPIIFAAAILQIPIFLAAPFQDNPVLQGIANFFNPTRPSGLFIEVLLVILFTYVYTAVQFDPKRIAESLREYGGFIPGIRPGEPTVKFLEHIVSRLTLWGALFLGLVTLLPQIIQNLTGIHSIAFSGIGLLIVVGVALDTLRQVESQLMLRSYEGFLSRGRLRGRNR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACSA_CAMJE
Sequence: MLNQNNQELFKPSKEFSRNARIKNLCEYYDLCDEAKEDFEGFWKRQAFEKIEWFSPFSRVLNEDKAPFYKWFEGGTLNVSYQCLDRHMKTRRNKAALIFEGEMGDYEVYTYRRLLHETCKAANLLKKFGVKKGDRVVIYMPMIPETAIVMLACARIGAIHSVVFGGFSPEALRDRIIDAGAKLVVTADGAFRRGKPYMLKPAVDKALSEGCESVEKVLIVIRNNEPIEYIKGRDYVYNELVKNESYKCEPEIMDSEDLLFLLYTSGSTGKPKGVMHASAGYILWAQMTMEWVFDIKDYDNYWCSADVGWITGHTYVVYGPLACGATTIMHEGTPTYPNSGRWWRMIEEYQISKFYTSPTAIRMLHADAPNEPRKYDLSTLEVLGTVGEPINPSAWKWFYDEIGGTKSPIVDTWWQTETGGHMITPLPGATPLKPGCATLPLPGIFAEVIDEEGNKKDEGEDGLLCITKPWPSMIRGIWGNDERYIESYFSQAKKDGKAVYFSGDGAFYDKNGYITITGRTDDVVNVAGHRIGTAEIESAIAKHPSVAESAVVSILDTIKGESLFAFVVLSPASSCDLGGAIETLKELNDILRVEIGPIAKIEKILYTPGLPKTRSGKIMRRILRTIARGEEIKQDISTLEDSKVVETIVKLAKAEFE
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: RNPA_STAA9
Sequence: MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: YGW4_YEAST
Sequence: MIVRLHAIYQDITRDYLPPASLNHLMLLSKQTQHKLSFKSAPIPDLQPFFKNFTSKTPGSAKESPCSSTAKISSSISISSQCIFNVVILSFVFTSQNLNLPSHPALHNVSPESLNDRLMTQLECANSPRLACELWVGTDKEPILSPNSVSYRVMQPNEFES
What are the official names of this protein?
Putative uncharacterized protein YGL214W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DEOD_CITK8
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKHIAETFLEDVREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVRNDVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGVDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKA
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: TRPB_FUSNN
Sequence: MTTENKKGYFGEFGGSYVPEVVQKALDKLEEAYNKYKDDEEFLKEYHHYLKNYSGRETPLYFAESLTNYLGGAKIYLKREDLNHLGAHKLNNVIGQILLAKRMGKKKVIAETGAGQHGVATAAAAAKFGMQCDIYMGALDVERQRLNVFRMEILGATVHAVEKGERTLKEAVDAAFKAWINNINDTFYVLGSAVGPHPYPSMVKDFQRVISQEARRQILEKENRLPDMIIACVGGGSNAIGAFAEFIPDKEVKLIGVEAAGKGLNTDRHAATLTLGTVDVLDGMKTYALFNEDGSVKPVYSISPGLDYPGIGPEHAFLRDSKRAEYVSATDDEAVNALLLLTKKEGIIPAIESSHALAEVIKRAPKLNKNKIIIVNISGRGDKDVAAIAEYLKNK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: G6PD_DROSI
Sequence: LWWLYRDDLLPKPTKFCGYARSMLTTETLKEQCLPYMKVQPHEQNKYEEFWALNDYVSGRYDGRTSFEVLNQRLEMMENKNKANRIFYLALPPSVFEEVTVNIKQVCMSLCGWNRVIIEKPFGRDDASSQALSDHLAGLFNEDQLYRIDHYLG
What is the function of this protein?
Cytosolic glucose-6-phosphate dehydrogenase that catalyzes the first and rate-limiting step of the oxidative branch within the pentose phosphate pathway/shunt, an alternative route to glycolysis for the dissimilation of carbohydrates and a major source of reducing power and metabolic intermediates for fatty acid and nucleic acid biosynthetic processes.
What are the official names of this protein?
Glucose-6-phosphate 1-dehydrogenase, G6PD, Zwischenferment.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL23_RIPO1
Sequence: MIPKNPRQLADLVLKPIITEKATRLLENNKYVFEVVPQATKPDIKAAIESLFDVSVIKVNTVRPPRKKKRVGRFIGYKPLYKRAIVTLQDGDTITLFPEV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: MINE_BRUC2
Sequence: MSIFRFFTRQQASAPQARERLQVLLAHERASYGGQSDLVAVLREEILAVIAKHIKVDREKVSVKMDRGDQVSTLEVDIELPLTAKKGRAA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: SSB2_SALTY
Sequence: MAARGVNKVILVGHIGQDPEVRYMPNGGAVANLTLATSETWRVRQDGEMREHTEWHRVVVFGKLAEIASEYLRKGAQVYIEGQLRTRKWTDQSGQDKYTTEVIVNVGGTMQMLGRHNSQPQQEPQTPPTAAKGEGKAVKGAGNAAKGKNAAAPQQPPAQPDPAYDFDDDIPF
What is the function of this protein?
Plays an important role in DNA replication, recombination and repair.  Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
What are the official names of this protein?
Single-stranded DNA-binding protein 2, SSB 2.
Protein: Y373_MYCS5
Sequence: MAGHSHSANIAHRKNAQDAARGKIFQKLSKEIFVAAQKGFDPEMNSALKLAISKAKAKNMPKDNIERAISKAKGDKNSNSFTETIFNATLSGGVSFIVTTLSDNLNRTRSNMTALFNKQNASLGKTGQIPFVFDHKGIIEFSKGELSEDDLMMVALENGAQEIETTDETFVLISNPEDFSQLKKALEDSFKIEEFLQCEILYLPNTYAEVSEEKQQKLLEFIDKLKDDDDVQDVYHNLDI
What are the official names of this protein?
Probable transcriptional regulatory protein MS53_0373.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANT_SHIF8
Sequence: MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPTGVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.