PharMolix/UniProtQA huggingface dataset:
Protein: GLGC_STRA1
Sequence: MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGINNVGVITQYQPLELNTHIGNGSSWGLDGIDSGVTVLQPYSATEGNRWFQGTSHAIYQNIDYIDRINPEYVLILSGDHIYKMNYDDMLQTHKDNLASLTVAVLDVPLKEASRFGIMNTDSNDRIVEFEEKPEHPKSTKASMGIYIFDWKRLRTVLIDGEKNGIDMSDFGKNVIPAYLESGERVYTYNFDGYWKDVGTIESLWEANMEYIGEDNKLHSRDRSWKIYSKNLIAPPNFMTEDANVKDSLVVDGCFVAGNVEHSILSTNVQVKPNAIIKDSFVMSGATIGEGAKINRAIIGEDAVIGDGVVIDGSKEVEVIGYKEVAGVPNED
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: SODM_STRP3
Sequence: MAIILPELPYAYDALEPQFDAETMTLHHDKHHATYVANTNAALEKHPEIGENLEELLADVTKIPEDIRQALINNGGGHLNHALFWELLSPEKQDVTSDVAQAIDDAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPILALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSELYQAAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAFF_MOUSE
Sequence: MAVDPLSSKALKVKRELSENTPHLSDEALMGLSVRELNRNLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPAALVAPASVITIVKSAPGPAPAADPAPCS
What is the function of this protein?
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves.  However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites.  Interacts with the upstream promoter region of the oxytocin receptor gene.  May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition.
What are the official names of this protein?
Transcription factor MafF, V-maf musculoaponeurotic fibrosarcoma oncogene homolog F.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PK21B_RHIME
Sequence: MSNSKDEVERIDWLEAELADTIDEDYELELSEPTLSEKIREIYRKAHPPALPRMDYFRALLALQAELIKLQDWVVYHKQKVVVIFEGRDAAGKGGVIKRITQRLNPRIVRTVALPAPSDREKTQWYFQRYVPHLPAGGEIVLFDRSWYNRCGVERVMGFATEEEVEQFFDDVPEFERMLVRSGVRLVKYWFSITDEEQQLRFLTRIHDPLKQWKLSPMDLQSRVRWEAYTKAKEETFARTNIREAPWHIVEANDKKRARLNCIDHLLKQIPYEDVPHEDITLPERIFNPNYERKVLPPELYVPAKY
What is the function of this protein?
Uses inorganic polyphosphate (polyP) as a donor to convert ADP to ATP.  Can also convert GDP to GTP, with lower efficiency.
What are the official names of this protein?
ADP-polyphosphate phosphotransferase 2, Polyphosphate kinase PPK2 2.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
Protein: BAC79_WEICO
Sequence: AIAVELARDVFEAIQTLSRGSVFQDMPLVSNKELMDLR
What is the function of this protein?
Has antibacterial activity against a wide spectrum of Gram-positive and Gram-negative bacteria, including L. monocytogenes which is inhibited through disruption of the cell membrane.
What are the official names of this protein?
Bacteriocin BAC79.
Protein: GLSA_PSEF5
Sequence: MQDLLNQILDEVRPLIGQGQVANYIPALADVPANQLGIAVYGNDGQVFSAGDADTPFSVQSISKVFSLVQAIGHSGEAIWERLGHEPSGQPFNSLVQLEFERGRPRNPFINAGALVICDINQSRFAAPALSMRDFVRRLSGNLQVMVDGRVAESEYQHRARNAAMAYLMQSFGNFHNDVEAVLRSYFSHCALRMSCVDLARAFCFLANDGFCKHSGEQILTRRQTQQVNSIMATSGLYDEAGNFAYRVGLPGKSGVGGGIVAVVPGQFTVCVWSPELNSAGNSLVGMAALELLSQRIGWSVF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: PSBN_EUCGG
Sequence: METATLVAISISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GDA2_WHEAT
Sequence: MKTFPILALLAIVATTATTAVRVPVPQLQLQNPSQQQPQEQVPLVQEQQFQGQQQPFPPQQPYPQPQPFPSQQPYLQLQPFPQPQLPYPQPQPFRPQQPYPQPQPQYSQPQQPISQQQQQQQQQQQQQQQILQQILQQQLIPCRDVVLQQHNIAHGSSQVLQESTYQLVQQLCCQQLWQIPEQSRCQAIHNVVHAIILHQQHHHHQQQQQQQQQQPLSQVSFQQPQQQYPSGQGFFQPSQQNPQAQGSFQPQQLPQFEEIRNLALQTLPAMCNVYIPPYCTIAPFGIFGTN
What is the function of this protein?
Gliadin is the major seed storage protein in wheat.
What are the official names of this protein?
Alpha/beta-gliadin A-II, Prolamin.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: SIPC_SALTS
Sequence: MLISNVGINPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSSKVSDLGLSPTLSAPAPGVLTQTPGTITSFLKASIQNTDMNQDLNALANNVTTKANEVVQTQLREQQAEVGKFFDISGMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAKTTASSMMREGMNALSGSISQSALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTTESHSIKNVLNGQNSVKLGAEGVDSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESLGIKDSNKQISPEHQAILSKRLESVESDIRLEQNTMDMTRIDARKMQMTGDLIMKNSVTVGGIAGASGQYAATQERSEQQISQVNNRVASTASDEARESSRKSTSLIQEMLKTMESINQSKASALAAIAGNIRA
What is the function of this protein?
Actin-binding protein that interferes with host cell actin cytoskeleton.  Nucleates actin polymerization and condensates actin filaments into cables (bundling).  SipA potenciates SipC activity and both are required for an efficient bacterial internalization by the host cell (By similarity).
What are the official names of this protein?
Cell invasion protein SipC, Effector protein SipC.
What is the protein family that this protein belongs to?
Belongs to the invasin protein C family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system 1 (SPI-1 TTSS) and inserted into the host cell plasma membrane.
Protein: BBX22_ARATH
Sequence: MKIQCNVCEAAEATVLCCADEAALCWACDEKIHAANKLAGKHQRVPLSASASSIPKCDICQEASGFFFCLQDRALLCRKCDVAIHTVNPHVSAHQRFLLTGIKVGLESIDTGPSTKSSPTNDDKTMETKPFVQSIPEPQKMAFDHHHHQQQQEQQEGVIPGTKVNDQTSTKLPLVSSGSTTGSIPQWQIEEIFGLTDFDQSYEYMENNGSSKADTSRRGDSDSSSMMRSAEEDGEDNNNCLGGETSWAVPQIQSPPTASGLNWPKHFHHHSVFVPDITSSTPYTGSSPNQRVGKRRRRF
What is the function of this protein?
Acts as positive regulator of seedling photomorphogenesis and light-regulated inhibition of hypocotyl elongation, independently and in concert with HY5 and BBX21 (PubMed:18540109, PubMed:18796637, PubMed:18182030, PubMed:21427283).  Acts as a positive regulator of de-etiolation and influences chloroplast biogenesis and function through regulation of genes encoding chloroplast proteins (PubMed:18182030).  Acts downstream of COP1 and plays an important role in early and long-term adjustment of the shade avoidance syndrome (SAS) responses in natural environments (PubMed:21070414).  Regulates the expression of genes responsive to light hormone signals which may contribute to optimal seedling development (PubMed:21427283).
What are the official names of this protein?
B-box zinc finger protein 22, Protein DOUBLE B-BOX 3, Protein LIGHT-REGULATED ZINC FINGER PROTEIN 1, Protein SALT TOLERANCE HOMOLOG 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNAJ_STAEQ
Sequence: MAKRDYYEVLGVNKSASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDENKRVNYDQFGHDGPQGGFGSQGFGGSDFGGFEDIFSSFFGGGSRQRDPNAPRKGDDLQYTMTITFEEAVFGTKKEISIKKDVTCHTCNGDGAKPGTSKKTCSYCNGAGRVSVEQNTILGRVRTEQVCPKCEGSGQEFEEPCPTCKGKGTENKTVKLEVTVPEGVDNEQQVRLAGEGSPGVNGGPHGDLYVVFRVKPSNTFERDGDDIYYNLDISFSQAALGDEIKIPTLKSNVVLTIPAGTQTGKQFRLKDKGVKNVHGYGYGDLFVNIKVVTPTKLNDRQKELLKEFAEINGENINEQSSNFKDRAKRFFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_MYCSK
Sequence: MTAAHVAAPEPGQYELSHLRLLEAEAIHIIREVAAEFERPVLLFSGGKDSIVMLHLAIKAFAPARLPFPVMHVDTGHNFDEVISTRDRLVAENGVRLVVASVQEDIDAGRVVDNGPSRNPLQTITLLRAIRENRFDAAFGGARRDEEKARAKERVFSFRDEFGQWDPKAQRPELWNIYNGRHRKGEHIRVFPLSNWTEYDIWAYIGAEGITLPGIYYAHTRPVFQRDGMLLAVHPYMQPRDDEEVFETSVRFRTVGDVTCTGCVESTASTVEDIIAETAVSRLTERGATRADDRISEAGMEDRKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: ARND_KLEP7
Sequence: MKQVGLRIDVDTFRGTRDGVPRLLELLGRHGIQASFFFSVGPDNMGRHLWRLVKPKFLWKMLRSRAASLYGWDILLAGTAWPGRRIGAGNEAVIRAAAESHEVGLHAWDHYSWQAWSGVWPQERLALEVERGLLELERIIGRPVTCSAVAGWRADQRVVKAKESFDFLYNSDCRGTRPFLPQLGSGVSGTVQIPVTLPTWDEAVGTAVDIAGFNRYLLDCIHRDAGVPVYTIHAEVEGIAYADQFNELLTMAAEEEIQFCPLSQLLPADFSELPSGKVVRGELAGREGWLGREQLLTSGI
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: CCD41_ORYSJ
Sequence: MAALTSYEMAASILLCAEDSSSVLGFGGEEEEEEEDVVAGKRARCAGPPPPPCVDVAGVDFAVPSEECVARLVETEADHMPREDYAERLRAGGGDGDLDLRVRMDAIDWIWKVHSYYSFAPLTACLAVNYLDRFLSLYQLPDGKDWMTQLLAVACLSLAAKMEETDVPQSLDLQVGEERYVFEAKTIQRMELLVLSTLKWRMQAVTPFSYVDYFLRELNGGDPPSGRSALLSSELILCIARGTECLGFRPSEIAAAVAAAVVGEEHAAFSHVNKERMSHCQEVIQAMELIHPKPSSPSRVFVSSSIPRSPTGVLDAAGCLSYRSDDSAVASHYAASSWGYEHDSSPVSSKRRKISR
What are the official names of this protein?
Cyclin-D4-1, G1/S-specific cyclin-D4-1, CycD4;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
Protein: RSME_RICPR
Sequence: MKYNRIYINSNLAENSKLELARDYVHYVKTVLRLKIHDSLRIFNGSDGEFLAQITQIGKNNLSVVLKEQLKKAYIESALTLAVAIIKSDKLMLTINMATQLGITKIIPLITRRCQFRTVNIERLMKCVIEATEQSERLNPPIIEQAITLKDYLKKNNNLILYANEHEKVKHSILHISSLLSKDIAIIIGPEEGLLMMS
What is the function of this protein?
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA.  Acts on the fully assembled 30S ribosomal subunit (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase E, 16S rRNA m3U1498 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RsmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_MYCPA
Sequence: MKSSGAGAAFAGASVADAAPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQRDPVLVFAGGSNLVISDALSDLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLGGLECLSGIPGSAGATPIQNVGAYGAEVSDTLTRVRVLDRGSGQVRWVPGTELEFGYRTSVFKRRADDGLEIPSVVLEVEFALDASGRSAPVRYGELAAELKVPVGQRADPRTVREAVLALRARKGMVLDAADHDTWSVGSFFTNPVVAPDVYERLAGSVDGPVPHYPAPGGVKLAAGWLVERAGFGKGYPVPDPGGPEAPCRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGITLVPEPVLLGCRL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROL_ECOBW
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSP5_NEOFI
Sequence: MGSNLPAQPNLRLTIIAADGLYKRDVFRFPDPFAVATVGGEQTHTTSVIKKTLNPYWNEMFDLRVNEDSILAIQIFDQKKFKKKDQGFLGVINVRIGDVIDLQMGGDEMLTRDLKKSNDNLVVHGKLIINLSTNLSTPNTNQANGLHRSHVQSSTSSGLVPQVAPSSSHPAASGAAPVDPSASNPSLNPQRVPSTTRPSSTAAPASAAGAAASNTHGSRTNLSSFEDSQGRLPAGWERREDNLGRTYYVDHNTRTTTWTRPSSNYNEHAQRSQREANMQLERRAHQSRMLPEDRTGANSPNLPESSQQAHTPPAGGSANAVSMMATGATTAGTGELPPGWEQRTTPEGRPYFVDHNTRTTTWVDPRRQQYIRMYGQNANGTNTTIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQGVPQYKRDFRRKLIYFRSQPALRIMSGQCHVKVRRNNIFEDSYAEIMRQSASDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGVNPEHLNYFKFIGRVVGLAIFHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGVLELTFSVDDEKFGERRTIDLKPGGRDIPVTNENKAEYVELVTEWKIVKRVEEQFNAFMSGFNELIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQESDEVIQNFWKVVRSWDAEQKSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKSGDPAALPKSHTCFNRLDLPPYKSYETLEHKMSIAVEETLGFGQE
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Probably involved in the regulatory network controlling carbon source utilization.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase hulA, HECT ubiquitin ligase A, HECT-type E3 ubiquitin transferase RSP5.
What is the protein family that this protein belongs to?
Belongs to the RSP5/NEDD4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2577_PSE14
Sequence: MSIESSSSESSPNADALHLNSSEVRVLGCLIEKQATNPETYPLTLNALVLACNQKTSRDPVMSLTPGQVGQSLRALEGRGLTRLVMGSRADRWEHRVDKAVELVPAQVILTGLLLLRGPQTVSELLTRSHRMHDFEDSEQLIHQLERLIARGLAMLAPRQSGQREDRYTHLLGDPDDLQELLAARQHAPERNAANPAASQRFDELEARVAALEERLARLE
What are the official names of this protein?
UPF0502 protein PSPPH_2577.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: ATPA2_BURP1
Sequence: MTPTPDAPAAADAATGAGWLARRRGALARVALAPVAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGALDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSCEVSHEADRDAAADAARVAGRAPGRAEPDRAAPRAMPDGPPRAQADGDRASASRPRPDARGDAARTAPSPQGGADANVDAEAEARHKR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MTIP_METAC
Sequence: MDEEAEVAEIAVLGGVGFNSHKDCESHPVTTPYGRITAYLTSIKGRSVVIIPRHAEEIHIPPHRVNYRGNIWAAHSLGAKRVISTNSVGSMRGHPVGSFVVLDDFIDFTRSRPSTFHDDKTVHVDVSEPYCPEIRASLRYSLEKRGISYTEGVYACTEGPRFETRAEIRMMSQFADVVGMTGVPEVVLAKELSLCYASLSIVTNQACGMTTQKLTADEVTEVVGKAQASIFKILSDAIGKIPETRNCMCRFAKEGACL
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis.  Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine.
What are the official names of this protein?
Probable S-methyl-5'-thioinosine phosphorylase, 5'-methylthioinosine phosphorylase, MTI phosphorylase, MTIP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: TRMD_LACAC
Sequence: MKINILTLFPDMFTPLQVSMLGRGLEDGKWDLNLVNFRDFTTDLHHHVDDTPYGGGAGMVLQIMPIKKALDSLPSTGKIIITAPQGKTFNEKMAQEWAKEDELTFICGHYEGFDQRVYDLADETVSIGDYVLTGGELPTMSMVDATVRLLPGILGNSASSVEESFSHGLLEYPQYTRPADFEGKKSARSFKPVVIIKRLLNGDTIRLLKATYLHRPDMLENRNLSDEEKKMLQEIKNEMNED
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EVE_DROME
Sequence: MHGYRTYNMESHHAHHDASPVDQKPLVVDLLATQYGKPQTPPPSPNECLSSPDNSLNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMPYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPAPPHPAGPHMHHPHMMGSSATGSSYSAGAAGLLGALPSATCYTGLGVGVPKTQTPPLDLQSSSSPHSSTLSLSPVGSDHAKVFDRSPVAQSAPSVPAPAPLTTTSPLPAPGLLMPSAKRPASDMSPPPTTTVIAEPKPKLFKPYKTEA
What is the function of this protein?
May play a role in determining neuronal identity.  May be directly involved in specifying identity of individual neurons.  Pair-rule protein required for segmentation; involved in transforming the broad, spatial, aperiodic expression patterns of the gap genes into a system of precise periodic expression patterns of the pair-rule and segmentary polarity genes.
What are the official names of this protein?
Segmentation protein even-skipped.
What is the protein family that this protein belongs to?
Belongs to the even-skipped homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VP6_ROTE2
Sequence: MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMVITMNGNEFQTGGIGNLPIRNWNFDFGLLGTTLLNLDANYVETARNTIDYFVDFVDNVCMDEMVRESQRNGIAPQSDSLRKLSGVKFKRINFDNSSEYIENWNLQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANTQQFEHIVQLRRVLTTATITLLPDAERFSFPRVINSADGTTTWYFNPVIFRPNNVEIEFLLNGQIINNYQARFGTIIARNFDTIRLSFQLMRPPPQNMTPAVAALFPNAPPFEHHATVGLTLRIESAICESVLADASETMLANVTSVRQEYAVPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RL18_STAA2
Sequence: MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQIIDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYHGRVKALAEAARESGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RLMM_AGGAN
Sequence: MNKLALYCRMGFEREMAAEITDKAAEKGVFGFVRVIENSGYVIFECYQADEADYLARELDFQQLIFARQMLVVSDLLTDLPQQDRITPIVQQYQQIADKIDLKQSTELLVETADTNEAKELLGFCRKFTVPLRQTLKKQGWLRASNHAKCGLFLHLFFLRNNACYVGYSYNHNHSAHLMGIQRLKFPADAPSRSTLKLEEAILTFIPRQKETEWLNENQYAVDLGACPGGWTYQLVKRGLFVYAVDHGKMAASLHETGRIEHCAEDGFKFQPPKRQKIDWLVCDMVEKPSRIAELMTKWLLNGWCHSMIFNLKLPMKKRYAEVQQCLQYIADKLTQRGLAFQLKAKHLYHDREEITVYLRLL
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_GOSHI
Sequence: MNPLISAASVIAAGLAVGLASIGPGVGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL33_SHEPC
Sequence: MAKAKGNREKIKLVSSAKTGHFYTTEKNKRNMPEKMEIKKFDPVIRQHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: KAD_BUCA5
Sequence: MRIILLGAPGTGKGTQGKFITEKYKIPQISTGDMLRESVVLKNKIGMIIKNIIEEGKLVSDEIVCHLIKNRIKKHDCINGFILDGFPRTIQQALYLSKKNIKIDYVLEFIIPHEYILERISGRRIHIQSGRIYHVKFKPPKIKDKDDLTGQTLITRKDDTKEGIKKRLEEYKKVHDPLVQYYIHEKKRGNIKFFQIDAMLSFSSIRKKLETILKK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.