PharMolix/UniProtQA huggingface dataset:
Protein: CAYP1_CANLF
Sequence: MDAVDATVEKLRAQCLSRGALGIQGLARFFRRLDRDRSRSLDSRELQRGLAELGLVLDTAEAEGVCRRWDRDGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRTHPKVQSGEWTEEEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMDTDEEFVAMMTSAWQL
What is the function of this protein?
Calcium-binding protein.  May play a role in cellular signaling events (Potential).
What are the official names of this protein?
Calcyphosin, Calcyphosine, Protein 5, Thyroid protein p24, TPP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_YERPA
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEVTTNAWVDIEEITRRTIREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRENPLEQGAGDQGLMFGYATNETSVLMPAPITYAHRLVERQAEVRKNGALPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEDINQKDLHEAVMEEIIKPVLPAEWITAHTKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVEAFGTEKIPADQLTLLVREFFDLRPYGLIKMLDLLHPIYRETAAYGHFGREHFPWEKTDKAALLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_FRATN
Sequence: MKLNTLAPAAGSKSAPKRLGRGIGSGLGKTSGKGHKGQKARSGGYHKVGFEGGQMPLQRRLPKFGFTSASKRYVAEIRLHELNNVVADEVTLDTLKDFGLIRKDIKTVKVIASGEIQKAVSLKGIACTKGAKEAIEKAGGKVE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PREL_DROME
Sequence: MVVAASTCRTETVFDYSWMNVVVAYWNRYPNPSSTHVLTEDTIQREVRDGKLFSRRLLSKTNPVPKWGARFYNNVPVKIVEDSVLDPVKKTFTTFTRNLGMTKIMKVDEIVVYSEQKDGSTLAVRRAYISSQVFGFSRAIRAFGIERFKANGNKASNGFNYVLRRMFPDSLVGGGHHQHAVTTTSPAGELPATTITVSTTNGSLNNQGALKSAAKVGYEFFKSHASKIAQLFSVKN
What is the function of this protein?
Involved in maintaining the structural and functional integrity of mitochondria (PubMed:19855018).  Activity is required for maintaining the subcellular distribution, shape and activity of mitochondria in neurons and as a consequence has an important role in the development and maintenance of dendritic arbors (PubMed:19855018).  Function may be particularly important in class IV dendritic arborization (da) neurons (PubMed:19855018).
What are the official names of this protein?
Protein preli-like.
What are the subcellular locations of this protein?
Mitochondrion. Note=Detected at the mitochondria cristae.
Protein: TILS_AQUAE
Sequence: MNPESRVIRKVLALQNDEKIFSGERRVLIAFSGGVDSVVLTDVLLKLKNYFSLKEVALAHFNHMLRESAERDEEFCKEFAKERNMKIFVGKEDVRAFAKENRMSLEEAGRFLRYKFLKEILESEGFDCIATAHHLNDLLETSLLFFTRGTGLDGLIGFLPKEEVIRRPLYYVKRSEIEEYAKFKGLRWVEDETNYEVSIPRNRIRHRVIPELKRINENLEDTFLKMVKVLRAEREFLEEEAQKLYKEVKKGNCLDVKKLKEKPLALQRRVIRKFIGEKDYEKVELVRSLLEKGGEVNLGKGKVLKRKERWLCFSPEV
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLE_STAA3
Sequence: MNKNIIIKSIAALTILTSVTGVGTTVVEGIQQTAKAEHNVKLIKNTNVAPYNGVVSIGSGTGFIVGKNTIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYKVKKIVRYSGQEDIAILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYINKFQMYESTGKVLSVKGNMIITDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKSTKGYGVYFSPEIKKFIADNTDK
What are the official names of this protein?
Serine protease SplE.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RN113_CAEEL
Sequence: MDLFRKPKKRNAPVVRKKESSSDEDQDSEVKDVIQKRRRTNPMVQSTKQLDASTRRADNSSDDSDDSDDNQDIAVATHSFAASGDAGPSGPRDQGATATLEVDTDYSHDAQAQFERVQQQLKEGVEKDGKILYKGSALYGAKEAKDTAKGNAASGYNRVGPVRAPQFLRQTVRWDFAPDICKDYKETGFCTFGDSCKFVHDRSDYKHGWEIDEEYEAGKYGAEDDANYEIHEGDDTFPEDCFICGNPFVDPIVTKCKHYFCTGCALKSFQKSSKCPICQQNTENIMNTAKELLTYLKRKKQQQKQEAEKQEEEKDSDDDEKPHECDDHHHHDHEDEPEEPENDSNVPEAEEKSDEEQEIMMEDVEGLEGGENDSESDDDDAEKD
What is the function of this protein?
May function as E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins.  May play a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit proteins involved in repair to sites of DNA damage by alkylating agents.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase rnf113, RING finger protein 113 homolog.
Protein: Y639_SYNY3
Sequence: MVNLLFLFFIMSFFPNNIFDYDQQAITDLLITASLKILFALAILLIGFWLSKRLQKLIIRALRKSNLEPTFISFAGNISYYLLLVVFFVLCLAQLGIQTSSLVALLGASTLAIGLALQGSLANVAGGILLVLFNYFRVGERIEVAGIEGIVESIEILSTTICTYDNRLVTIPNKQIIENNIINHVGKPERRIDLVIGVGYEEDIDHVRSSLQWVIDQNSEVCTEPAPTIALGELGDSSVNFYVRPWVKSEDYFRLKLQLTEAIKRKLDEENISIPFPQRDVHLIQPETKELDIKAA
What are the official names of this protein?
Uncharacterized MscS family protein slr0639.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUD_ECO27
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVQANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: MAEL2_DROPS
Sequence: MAQNKPNAFMAFVADWRACNRFGRGLSTSEAVAKCGPIWEGMSDRERGQYKSKAKDSNVLERESKTERLNCPGVHSKMQVEKNEAIDAELQMKRNIKRIVLKATNSMKLEEREFLFVSFNYFTKALNGDVYQPAELSACRFSLKGGISSNYSTMINPGHIIFGQTSDAQDHSRTTHKLPLPPNAMGEKNLGNLYSDTLKWLSASNDEEDEQYDHPVIVYTTPELMPVVKSCFRYLACEGDTDKHAEKIMVYDICYLFLTLKKTVLDLVGVPSDHMNIHVTNSFFRRDFFEFSSGIACDYHEEVDRTKYCTKSMVLRWGYMISHYICGDLAIPLQPRKHVPIEVKHSYTVTPGDSSLALDGTWTDSGYSGY
What is the function of this protein?
Involved both in the piRNA and miRNA metabolic processes.  As a component of the meiotic nuage, plays a central role during oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Repression of transposable elements is mediated via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the repression of transposons.  As a nuclear component, it is required for proper differentiation in the germline stem cell (GSC) lineage by repressing microRNA-7 (miR-7), thereby acting as an indirect regulator of bag-of-marbles (Bam).  Acts by binding to the promoter of miR-7 gene and repressing its expression; miR-7 repression alleviates the Bam repression by miR-7, thereby allowing differentiation in the germline stem cell (GSC) lineage (By similarity).
What are the official names of this protein?
Protein maelstrom 2.
What is the protein family that this protein belongs to?
Belongs to the maelstrom family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis.
Protein: PCH2_MOUSE
Sequence: MDEAVGDLKQALPCVAESPAVHVEVLQRSGSTAKKEDIKSSVYRLLNRHNIVFGDYVWTEFDDPFLSRNVQSVSIVDTELKAKDPQPIDLSACTIALHIFQLNEEGPSSENLDEETENIIAASHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTVLFSDKNVDSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVESLTAARNACRAGAEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSLLLSEISRKSEGLSGRVLRKLPFLAHALYIQAPSVTIEGFLQALSLAVDKQFEEKKKLSAYV
What is the function of this protein?
Plays a key role in chromosome recombination and chromosome structure development during meiosis.  Required at early steps in meiotic recombination that leads to non-crossovers pathways.  Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.  Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation.  In males, required for efficient synapsis of the sex chromosomes and for sex body formation.  Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes.  Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (PubMed:17696610, PubMed:19851446, PubMed:20711356).  Plays a role in mitotic spindle assembly checkpoint (SAC) activation (By similarity).
What are the official names of this protein?
Pachytene checkpoint protein 2 homolog, Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. PCH2 subfamily.
Protein: FABZ_PSELT
Sequence: MNIDEIKQILPHRFPMLLVDRIVEKSEDHAKAIKNVTASEIFFLGHFPAYPIYPGVLIIEGLAQTAGLMLLNRGESVIPVFAGIDNARFKSEVRPGDVLEYEVWLKERKLGMAKVEAIAKVQGKIVATATLLVGVRKNEK
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNT2_RAT
Sequence: MATPAAVNPPEMASDIPGSVTLPVAPMAATGQVRMAGAMPARGGKRRSGMDFDDEDGEGPSKFSRENHSEIERRRRNKMTQYITELSDMVPTCSALARKPDKLTILRMAVSHMKSMRGTGNKSTDGAYKPSFLTEQELKHLILEAADGFLFVVAAETGRVIYVSDSVTPVLNQPQSEWFGSTLYEQVHPDDVEKLREQLCTSENSMTGRILDLKTGTVKKEGQQSSMRMCMGSRRSFICRMRCGNAPLDHLPLNRITTMRKRFRNGLGPVKEGEAQYAVVHCTGYIKAWPPAGMSIPEEDADVGQGSKYCLVAIGRLQVTSSPVCMDMSGMSVPTEFLSRHNSDGIITFVDPRCISVIGYQPQDLLGKDILEFCHPEDQSHLRESFQQVVKLKGQVLSVMYRFRTKNREWLLIRTSSFTFQNPYSDEIEYVICTNTNVKQLQQQQAELEVHQRDGLSSYDLSQVPVPNLPTGVHEAGKPVEKADAIFSQERDPRFAEMFAGISASEKKMMSSASASGSQQIYSQGSPFPAGHSGKAFSSSVVHVPGVNDIQSSSSTGQNISQISRQLNQGQVAWTGSRPPFPGQPSKTQSSAFGIGSSHPYPADPSSYSPLSSPAASSPSGNAYPSLANRTPGFAESGQSGGQFQGRPSEVWSQWQSQHHGQQSGEQHSHQQPGQTEVFQDMLPMPGDPTQGTGNYNIEDFADLGMFPPFSE
What is the function of this protein?
Transcription factor that plays a role in the development of the hypothalamo-pituitary axis, postnatal brain growth, and visual and renal function.  Specifically recognizes the xenobiotic response element (XRE).
What are the official names of this protein?
Aryl hydrocarbon receptor nuclear translocator 2, ARNT protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: HLYAP_ECOLX
Sequence: MTTITTAQIKSTLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQGSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNILGGGAENIGDNLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSELAKASIELINQLVDTVASLNNNVNSFSQQLNTLGSVLSNTKHLNGVGNKLQNLPNLDNIGAGLDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHWDTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKXDEFQKQVFDPLKGNIDLSDSKSSTLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGAVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDFRDVAFKREGNDLIMYKGEGNVLSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSGRIITPDSLKKALEYQQRNNKASYVYGNDALAYGSQGDLNPLINEISKIISAAGSFDVKEERTAASLLQLSGNASDFSYGRNSITLTTSA
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by forming a pore.
What are the official names of this protein?
Hemolysin, plasmid.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein: FLGI_ECOK1
Sequence: MVIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDARTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINLRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: CYOE_FRATT
Sequence: MYFKRYLQLAKPGIIFGNLITLTGGFLLATHREIGFEYLPLFVYVMIGVALMIAAGCVFNNIYDKDIDSSMTRTQNRPLVTGDISVIQATIYGTILLILSCLVLYYLVILLTLWIIIIGFIVYVGIYTVSKRLTIHATVLGGISGAIPPVAGYTAVVNILDYNALALFLILFFWQIPHSYAIAMLYIDDYKKVKLPMLPIVKGIAYTKKIMLFYLALFVVSCALPAVLGSADLFSFIVCMLVALFWMYKSIQSYRTDTDRVFAKTVFKFSIIVITVICLTMG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARLR_STAS1
Sequence: MTKILIVEDEQNLARFIELELEHENYDVDIEYDGKPGLEKALSNTYDLILLDLMLPNINGLEICRQIRQNQTTPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAMLRRQPQKNLIDIKGIIIDKDAFKVTVDGQPLDLTKTEYDLLFLLVENRNHVLQREQIITDVWGYDTEVETNVVDVYIRYLRNKLKPFGKDKCIETVRGVGYVVRQ
What is the function of this protein?
Member of the two-component regulatory system ArlS/ArlR.
What are the official names of this protein?
Response regulator ArlR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIKE_BRUA2
Sequence: MSLISADNIVKIYQSHSLVGASARKTMLHDISISIGQGETVALLGRSGCGKSTLARLLVGLERPTSGEVRFRGVPLTKLDRSGMKAFRREVQLIFQDSPGAVNARSSVRAIIGEPLRHLTSLDETRREERIQELLRLVELPPEIADRLPAQVSGGQLQRICIARALAVNPKLIILDEAVSNLDIHLQASALALLTKLQQEGGIAYLFVTHDLRLVQKFAARCLVMDEGQIVEEIKTADLDSMRHPASRLLREAVLPPLPVRAVETN
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYA_CLAM3
Sequence: MQTADIRNAWLTYFGDRGHTVVPSASLVSDDPTLLFTVAGMVPFVPYLTGVVPAPFPRATSVQKCIRTLDIEEVGRTPRHGTFFQMNGNFSFGDYFKEQAIAYAWELLTTSEADGGLGFSPDDLWVTVYHEDDEARQAWKRIAGLPDERIQGLGRDTNYWHTGQPGPAGPCSEIFFDRGPAYGADGGPATDDDRYVEIWNLVFMQYLRGAGTGKSDFEILGDLPKKNIDTGMGLERVAFLKQGVENMYEIDQVRPVLDRAAELSGRRYGADHEDDVRMRIVADHVRSSLMLMSDGVRPSNEGRGYILRRLMRRTVRAMRLMGVDAATFGELFPASRDAMKAAYPEVSDDFDRISRLAYAEEETFLRTLSGGTTILDVAVGETKAKGGERIAGDTAFLLHDTFGFPIDLTLEMAEENGLTVDREAFDRLMLEQRTRAKADAKSKKTALADLTVYSEFRAAGETRFTGYDELETGTTILGLIVGGRSVDHAVAGDIAEVILPETSLYAESGGQEADAGSIVGQGFDLEVLDVQKPVKGLISHRVQVRSGEVGVGDAATTVVDADWRRGATQAHSGTHLVHAALRQVLGQDAHQSGSYNRAGYMRLDFAWNQALSSETRSEIEDIANGAVRDDLRVVTRVMPIDEAKQLGAMALFGEKYGDTVRVVDIGGPWSRELCAGTHVSSSAQIGLINVVGESSVGSTNRRIESLVGREAFQDLAVERAIVSQLTSTLKTPREQLPDRIADLMQNLKTAERRIADFEAQALQQRVPALLAQGSRVGAVTLIQESLGAVRSADEVRQLVTLVRERAGSEPVVVALAGDAGGKPTVIVATNQAARDAGAKAGQLARAAAAVLGGGGGGKDDLAQGGGSDVSAIGDALTAVRQALAS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GALU_SHIFL
Sequence: MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHVTIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFDETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRYVLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHNTLGTEFKAWLEEEMGIKK
What is the function of this protein?
May play a role in stationary phase survival.
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, Alpha-D-glucosyl-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, Uridine diphosphoglucose pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: TPIS_SYNP2
Sequence: MRKIIIAGNWKMYKTQAESLDFLKALLPKIADDHEEREVVLCTPFTDLGLMSKSLHGTRVRLGAQNIHWADEGAFTGEISGSMLTEMGVRYVIVGHSERRQYFGETDETVNQRLKAAQRHGLTPILCVGESKAQRDAGETEAVIFAQLEQDLVDIDQNNLVVAYEPIWAIGTGDTCDATEANRVIGLIREKLTNKNVTIQYGGSVKPNNVDEIMAQPEIDGALVGGASLEAESFARLVNYV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALOX_PICAN
Sequence: MAIPDEFDIIVVGGGSTGCCIAGRLANLDDQNLTVALIEGGENNINNPWVYLPGVYPRNMRLDSKTATFYSSRPSKALNGRRAIVPCANILGGGSSINFLMYTRASASDYDDWESEGWSTDELLPLIKKIETYQRPCNNRDLHGFDGPIKVSFGNYTYPTCQDFLRAAESQGIPVVDDLEDFKTSHGAEHWLKWINRDLGRRSDSAHAYVHPTMRNKQSLFLITSTKCDKVIIEDGKAVAVRTVPMKPLNPKKPVSRTFRARKQIVISCGTISSPLVLQRSGIGAAHHLRSVGVKPIVDLPGVGENFQDHYCFFTPYYVKPDVPTFDDFVRGDPVAQKAAFDQWYSNKDGPLTTNGIEAGVKIRPTEEELATADEDFRRGYAEYFENKPDKPLMHYSVISGFFGDHTKIPNGKFMTMFHFLEYPFSRGFVRITSANPYDAPDFDPGFLNDERDLWPMVWAYKKSRETARRMESFAGEVTSHHPLFKVDSPARARDLDLETCSAYAGPKHLTANLYHGSWTVPIDKPTPKNDFHVTSNQVQLHSDIEYTEEDDEAIVNYIKEHTETTWHCLGTCSMAPREGSKIAPKGGVLDARLNVYGVQNLKVADLSVCPDNVGCNTYSTALTIGEKAATLVAEDLGYSGSDLDMTIPNFRLGTYEETGLARF
What is the function of this protein?
Catalyzes the oxidation of methanol to formaldehyde and hydrogen peroxide, the first step in the methanol utilization pathway of methylotrophic yeasts.
What are the official names of this protein?
Alcohol oxidase, AO, AOX, Methanol oxidase, MOX.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: TRA2_CAEEL
Sequence: MKLKYNKLLVSVVIVTFVTFGLLLAECFGKSIDYQEKSIFPSFVSQGFFETRTNNEEYIIEKIAQTQENGVDMRSTLHFTQHGYLLNNISNLKIKFRQKTYTLNDVCFKPHITIFQQSSSSDQNEYPHYIQRLLLEMQRLSPCLIVTPLNCFYDIYRIHGEISNWNKNTDFLNRRLRNSYIEAIGENDERPYVKSNYGPSLIKSWADHMFDLPSKSFTNSTKDALFQKIKLWLLSIEPRQKTCAASIHSCDTPLDSEHYFNICTDMQSVDNFAEKKTKFKLEDVDEEFAMNLDCVDDQEQFIEWMQELEIRKMYSHVTEKPDYPNVVNQTCDKIFHDLNSTGIEFFDGSRSFSSTKSQFDTMQTEIVLLTPEMLLSAMQHSDFVNGFESIWTIEKAEELIHEFRLALKEETEKFKENRMSKMIRVTSRVLDNTVTTKLQSFSEKQTIHFVVNVHSLIVILFTIFVWSGAPLRSAFMFFVRDALTCLLFCFVCSTDGVIVLDTELIKYIIVLTLANLYFTTRSSFCTERLSRCIQREKRFPINSNFASLITVDTMTDSRQIQYFLSTVTKYQAAQDSYSNELFERFPKNWGCTSILIFPIVFVYWYFIDSNFDKICVSVLPSFCLAAGEELFAKNMFWKEREAMQAKQRLENEEQAESITGSSLEKLFAGNKPVSNTDKANIVKKSSIIRNQKPCLQDLSPGTYDVSNFMKYPHQASRIFREKIIGLYLRILKLRTLGVILCIPAILLIVISIGLLFIPVKRETLHTDSKQDDIFIEFEIFNFSTNWKIVNQNLKQFSEDIESIGTLYTISNWQKSFERFEQETNKNASAEWNILFKWINDEPINSAVTLFSEKSSGNQTIANPFKFRLRYGFDAKNETTVIEIVQKIDELLSKCSKNLSPKAVGVLYEHYHRIAVVWNLFAFNQLTTAGIFIILLSIITFIFAITPTIKATFLFSLLVVGTQIEVAALVHLFSLDHHQIYTNLALFAGFLAAWDPFCALLRYRRRILYKSETRRTPELASKRRVLLPIVATADIAQFFVLLITAFSILAIICSIVPELNIFFVPTVILIVIQIVAVFNSIIVSIATKQMFESEVRHYLHRDLRGSTTAVRVYNLVQKQRLASSLDEPQVELDEFSIKRSSPPCRYYAPPPKYSCKKRSRSSDEDEDSDPNQPGPSNRRSPKTGNKRVRGNGDNTELYIPNRYELIVSGKSVGGNTSAAWNGPGSTLEQNMNALEECFELGVDEYDFDEHDGDEGCELVQDMLDRERNLMNKRSTAQRRESRNIEKMKKSQENLDKEKSEEKISESKKNQDDSIESPNLPGTPANLPVDEPLPPVGRLYIVEHVLPEEYRRDPLTEPPSMEDCIRAHSDPNLPPHPRADQYPASFTRPMVEYCEDIYWTHRTGQLPPGLQVPRRPYDYYHITERTPPPEDLNWVPPAESPPIPIPQQAFDLLEERRRNHREQQDEAREGDLSDPEV
What is the function of this protein?
Plays a major role in controlling sexual cell fates.  Promotes female development in XX animals where it sequesters one or more of the FEM proteins to the membrane thereby freeing the tra-1 protein (a putative transcription factor) to enter the nucleus and promote female development.  In XO animals it acts as a receptor for her-1 which prevents it from binding to FEM proteins thereby repressing the activity of tra-1.  Negatively regulates male development when bound to fem-3 and is required together with tra-1 for promoting spermatogenesis.  Also required for feminizing tra-3 activity.
What are the official names of this protein?
Sex-determining transformer protein 2, Ce-Tra-2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CCNT1_BOVIN
Sequence: MEGERKNNNKRWYFTREQLENSPSRRFGLDPDKELSNRQQAANLLQDMGQRLNVSQLTINTAIVYMHRFYMIQSFTQFHRNSVAPAALFLAAKVEEQPKKLEHVIKVAHTCLHPQESLPDTRSEAYLQQVQDLVILESIILQTLGFELTIDHPHTHVVKCTQLVRASKDLAQTSYFMATNSLHLTTFSLQYTPPVVACVCIHLACKWSNWEIPVSTDGKHWWEYVDATVTLELLDELTHEFLQILEKTPNRLKRIWNWRAWQADRKTKADDRGADENSSEQTILNMISQSSSDTTIAGLMSMSASSTTSAVPSLPATEDSKSNLSNVEMLSSERWLSSHPPFKVEPAQGYRKSENLALVGADHSLQQDGSNAFVSQKQNSKSVPSAKVSLKEYRAKHAEELAAQKRQLENMEANVKSQYAYAAQNLLSHHDSHSSVILKMPIEGSENPERPFLEKTDKTALKMRIPMTGGDKAASIKPEEIKMRIKVHTAADKHNSVDDSVTKNREHKEKHKTHPSNHHHHHNHHSHKHSHSQLPAGTGNKRLGDPKHSSQTSTLAHKPYSLSSSFSSSSSSRKRPLPEETGGVAYDHSTKTAKSAKSSSINFSFPPLPTMAQLPGHSSDTSGLHFSQPSCKTRVPHMKLDKSSTGANSHNTPQTTDYQDTVNMLNSLLNAQGVQPTQPPAFEYVHSYGEYMNPRAGGMSSRSGNTDKPRPPPLPSEPPPPLPPLPK
What is the function of this protein?
Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II).  Required to activate the protein kinase activity of CDK9: acts by mediating formation of liquid-liquid phase separation (LLPS) that enhances binding of P-TEFb to the CTD of RNA Pol II.
What are the official names of this protein?
Cyclin-T1, CycT1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.