PharMolix/UniProtQA huggingface dataset:
Protein: HGS_MOUSE
Sequence: MGRGSGTFERLLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQVEVNVRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFPEFKESDAMFAAERAPDWVDAEECHRCRVQFGVVTRKHHCRACGQIFCGKCSSKYSTIPKFGIEKEVRVCEPCYEQLNKKAEGKASSTTELPPEYLTSPLSQQSQLPPKRDETALQEEEELQLALALSQSEAEEKERMRQKTTYTAHPKAEPTPLASSAPPAGSLYSSPVNSSAPLAEDIDPELARYLNRNYWEKKQEEARKSPTPSAPVPLTEPAAQPGEGHTAPNSMAEAPLPETDSQPITPCSGPFSEYQNGESEESHEQFLKALQNAVSTFVNRMKSNHMRGRSITNDSAVLSLFQSINTMHPQLLELLNQLDERRLYYEGLQDKLAQIRDARGALSALREEHREKLRRAAEEAERQRQIQLAQKLEIMRQKKQEYLEVQRQLAIQRLQEQEKERQMRLEQQKQTVQMRAQMPAFPLPYAQLQAMPTAGGVLYQPSGPTSFPATFSPAGSVEGSPMHGVYMSQPAPATGPYPSMPGTTADPSMVSAYMYPTGAPGAQAAPQAQAGPTTSPAYSSYQPTPTPGYQSVASQAPQSLPAISQPPQTSNIGYMGSQPMSMGYQPYNMQNLMTALPGQDASLPAQQPYIPGQQPLYQQMAPSTGPPQQQPPVAQPAPTQGPPAQGSEAQLISFD
What is the function of this protein?
Involved in intracellular signal transduction mediated by cytokines and growth factors.  When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF.  Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin.  May concentrate ubiquitinated receptors within clathrin-coated regions.  Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex).  The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.  May contribute to the efficient recruitment of SMADs to the activin receptor complex.  Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
What are the official names of this protein?
Hepatocyte growth factor-regulated tyrosine kinase substrate.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Endosome, multivesicular body membrane; Peripheral membrane protein. Note=Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments.
Protein: PROB_STRP3
Sequence: MMKRQFEDVTRIVIKIGTSSLVLPTGKINLEKIDQLAFVISSLMNKGKEVILVSSGAMGFGLDILKMEKRPTNLAKQQAVSSVGQVAMMSLYSQIFAHYQTNVSQILLTRDVVVFPESLANVTNAFESLISFGIVPIVNENDAVSVDEMDHATKFGDNDRLSAVVAGITKADLLIMLSDIDGLFDKNPTIYEDAQLRSHVAVITQEIIASAGGAGSKFGTGGMLSKIQSAQMVFENKGQMVLMNGANPRDILRVLEGQPLGTWFKQIEEVRHD
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_VIBVY
Sequence: MIIPALDLIEGQVVRLYQGDYGQVTEYKVDPAEQFNLYHQAGANWLHLVDLTGAKDTTARQLDLIAKLLASTPANIQIGGGVRTEQDVIDLLEAGAQRVVVGSTAVKQPELVKGWMEKYGAEKIVLALDINIDQDGTRKVAISGWQEDSGVTIEALINDYLTVGLQHVLCTDISRDGTLEGSNVELYVDLCKQYPQVQFQSSGGIGSLADIEALKGSGVAGVIVGRALLDGKFTAEEAFACWQSE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_LACP7
Sequence: MALMDFFKKKASGSVAKDRLKLVLVSDRAGCSPEIMEQIKNDIIAVISKYIVIDQEGLDIKITQTESEGNNGNVPALFANIPIKDLKHSK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RLMKL_ECOLC
Sequence: MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLVYQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLHLRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGLHRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNARLAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMKNQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVAEDYTNRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTIDAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNAHLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKRMEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKTLSQDFARNRQIHNCWLITAA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF2_TTVE1
Sequence: MQRRTQELIWKELVDNSHKLFCNCMDPQNHYRLICQNLNREPGEPWRTAGGIGEGGAGGDGAAAGGEGDVHGRPAGAEDGEDGADAAMAAALAAFEDATG
What are the official names of this protein?
Uncharacterized ORF2 protein.
Protein: SECE_PYRHO
Sequence: MPEFQERVRNFFKESKRVFLVTKKPGWEEYKKAAKITGLGILVIGLVGMLIRIIGILMLGG
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE, Protein transport protein Sec61 gamma subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HEMH_PECAS
Sequence: MKQEKYGVLMVNLGTPDAPTPQAVRRYLAEFLSDRRVVDTPRLLWWPLLRGIILPIRSPRVAKLYQSVWMEGGSPLLVISRRQHQALAARMPDTPVELGMSYGSPSLRSALDKLLAQGVTQLVVLPMYPQYSCSTTAAVWDGLAAQLRDNRQLPAIRFIRDYAEHPAYIAALKHRVEQSFAEHGEPDRLVISYHGIPVRYANEGDDYPQRCRATTEALIAALGLPEGKIMMTFQSRFGREPWLTPYTDETMQGLPAQGIKHIQIMCPGFAADCLETLEEIQEQNREIFLHAGGEAFHYIPALNDDPLHIDLLEQLVGKVE
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPT_ECO27
Sequence: MKRISTTITTTITITTGNGAG
What is the function of this protein?
This protein is involved in control of the biosynthesis of threonine.
What are the official names of this protein?
thr operon leader peptide, thr operon attenuator.
What is the protein family that this protein belongs to?
Belongs to the thr operon leader peptide family.
Protein: MATK_DIAEN
Sequence: MEELQGYLEKGESRQQHFLYPLLFQEYIYALAHDYSLNSSIFYEPMEIFGYDNKSSLALVKRLIIRIYQQNSLISSVNDSNQNRLLWHNHFFYSHFYSQMISESFGILVEIPFSLRLVSYFEEIEISKYXNLRSIHSIFPFLEDKLSHLNYVSDILIPHPIHMEILVQILQCWIQDVPFLHFLQFFLREYHNWNSLLITQKKSIYVFSKENKRLFRLLYNSYAFECEFLFXFIRXQSYYLRXISYGTFLERTHFYGKIEHLQIEHFIFIVVCRNYFHRTLWLFKDSFMHYVRYEGKAILASKGTGTPLLMKKWKYLFFHFWQYYFHFWSQPYRIHISPLSKHSFYFLGYLSSLLRNFLAVRNQMLDNSFLTDTIIKKLDTTVPVILLIGSLSKAKFCTVSGHPISKPIWADLPDSDILDQFGRICKNLSHYHSGSSKKRDLYRIKYILRLSCARTLARKHKSTVRTFLRRLGSGLLEEFFTEEEQVLSLIFPKTTPFILHGSHRERIWYLDIIRINDLVNYS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EDM2_ARATH
Sequence: MTFVDDDEEEDFSVPQSASNYYFEDDDKEPVSFARLPIQWSVEEKVDGSGLGFYLRGRSDNGLLPLHKLVKAWRYDLSNFQPEISVLTKDNIWIKLEEPRKSYGELIRTVLVTLHSIQFLRRNPQASEKALWEKLTRSLRSYDVKPSQNDLVDHIGLIAEAAKRDRNLANSKFILAFLTKKPTKRRLPDEDNAKDDFIVGDEDTYVASDEDELDDEDDDFFESVCAICDNGGEILCCEGSCLRSFHATKKDGEDSLCDSLGFNKMQVEAIQKYFCPNCEHKIHQCFICKNLGSSDNSSGAAEVFQCVSATCGYFYHPHCVTRRLRLGNKEESEALERQIIAGEYTCPLHKCSVCENGEVKTDSNLQFAVCRRCPKSYHRKCLPREISFEDIEDEDILTRAWDGLLHNRVLIYCQEHEIDEELLTPVRDHVKFPFTEEQKVFVKEQRRILESHVGRDKARLKVKDPALQDTCGKASKNSFRSSFPSSKDGFSTKKHGLVSSVPDHSRKRKDIDPSIKHKMVPQKSQKMMEDSREAGKNKLGVKEARDAGKSKISLGERLFSYTQEPNPVKPGRVIPVDSKHNKTDSIASKEPGSEIPTLDNDSQRRLLAVMKKATEEITMGTILKKFKIQSTMSTHSTRNVVDKTITMGKVEGSVQAIRTALKKLEEGGNIEDAKAVCEPEVLSQILKWKDKLKVYLAPFLHGARYTSFGRHFTNPEKLQQIVDRLHWYADDGDMIVDFCCGSNDFSCLMNAKLEETGKKCLYKNYDLFPAKNNFNFERKDWMTVSKDELEPGSKLIMGLNPPFGVNASLANKFITKALEFRPKILILIVPPETERLDKKKSSYVLIWEDKTFLSGNSFYLPGSVNEEDKQLEDWNLVPPPLSLWSRSDFAAKHKKIAEKHCHLSRDVGSSKLKIVEEEANASLHPLGASDGMCDDIPMEKDELEVAECVNKILVSEKIDTVETVARVHQSDHLSRRSQLKKEGKTKDYSGRKLGKSMDSNNVDWKSNDMEEDQGELSRAPESIKVKIPEMTSDWQSPVRSSPDDIYAVCTSISTTTPQRSHEAVEASLPAITRTKSNLGKNIREHGCKVQGTGKPEVSRDRPSSVRTSREDIYTVRPSPENTGQKPFEAFEPSYGASLSHFDDGLAAKYGGFGGGYRMPDPPFLPDQFPLRNGPNEMFDFRGYSDLDRGIGQREYPQQYGGHLDPMLAPPPPPNLMDNAFPLQQRYAPHFDQMNYQRMSSFPPQPPLQPSGHNLLNPHDFPLPPPPPSDFEMSPRGFAPGPNPNYPYMSRSGGWIND
What is the function of this protein?
Cellular antisilencing factor and regulator of genome DNA methylation patterns involved in the regulation of chromatin states.  Together with SUVH4, monitors repressive epigenetic marks H3K27me1, H3K9me2, and prevents DNA-methylation at CHG sites, affecting especially the expression of transposons and developmentally important genes (PubMed:21830950, PubMed:23609044, PubMed:24248388).  Regulates alternative RNA processing such as distal 3' polyadenylation by intronic heterochromatin (PubMed:24248388).  Epigenetic reader that binds DNA and contributes to transcriptional transposable element (TE) silencing by modulating levels of the repressive post-translational histone modifications (PHM) H3K9me2 (PubMed:23609044).  In cv.  Columbia, required for RPP7-dependent disease resistance against the Hyaloperonospora arabidopsidis isolate Hiks1, by promoting levels of RPP7 via alternative polyadenylation (APA), resulting from cooption of epigenetic information at the TE insertion locus COPIA-R7 (PubMed:23940361, PubMed:17253987, PubMed:20149132).  Regulates development processes such as the formation of leaf pavement cells, leaf expansion, fertility and flowering (PubMed:20840782, PubMed:20149132, PubMed:23609044).  Prevents FLC accumulation to control flowering (PubMed:23976921).  Modulates stomatal development by regulating the methylation-mediated silencing of ERECTA receptor genes (e. g.  ER, ERL1 and ERL2) and preventing cell divisions (PubMed:27697902).
What are the official names of this protein?
Protein ENHANCED DOWNY MILDEW 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPG_SALPB
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYDVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRARGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNDDMIAQLESRIRAKASQLDEARRIDVLQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: Y218_RICPR
Sequence: MKKISTFIITKNESARIARAINSVKNITDEVIVVDNESTDDTVHIAKTLGAQVIVKPWLGYVGQKSFAESMCVNDWVLNIDADEELSQELQDEIEYIFTSHNQDRYLAYQIKLLIMYRGDQKPRMFAPLNKCTRLYNKKFASFANTINSTTHDSVVFNKDVDFTGKIYLLNGIAYHYSGTSIEQLVNKANFYSSEQAKDLVKQGKKLSNFRLATEMIWCFLKAFFIRRYFVFGFDGFVDSIIFAFARFLRLAKLRDLSLKSQNVITSDNYINYCMDFKSLLQQKKRNRYPKK
What are the official names of this protein?
Uncharacterized glycosyltransferase RP128.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. WaaE/KdtX subfamily.
Protein: ATPE_XANC5
Sequence: MSTIRCDIVSAEKEIFHGEATLVVATGELGELGIAPKHAPLITRLKPGKVVVTTANGEQLDFAISGGILEVQPQVVTILVDTAVRAQDIDEAAVRKVKEEAERLLANRGNTVDVAEAQRQLAEATVQLQALERLRRNLKH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NADA_PROM3
Sequence: MVRMTAVCTAKTVSPVPSTRKEFKGAIAELRKKLNAVILAHYYQDPEIQDIADFIGDSLELSRRAASTNADVIVFCGVHFMAETAKILSPEKIVLLPDLEAGCSLADDCPADEFAAFRDKHPDHIVVSYINCTAAVKAQSDLICTSSNAVALVSQLPKDRPILFAPDQNLGRWVQKQSGRELTIWPGRCMVHETFSEEALLKLKMMHPEAKVIAHPECLERLLELADYVGSTSKLLEYTETNPGTKFIVLTEPGILHQMKQRMPNKEFMDVPGIDGCSCNECPYMRLNTLEKLWRCLSTMKPSIEIEEGVRQKALIPIQRMLNMKEKQEASQH
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_SHEB8
Sequence: MSQEFAHLSVLLAETVGGLNIKDDGIYIDGTFGRGGHSRQVLQQLGENGRLIAIDRDPQAIEAAKQFADDPRFQIVHGGFGQLADYVEELGLVGKIDGVLLDLGVSSPQLDDAERGFSFMRDGPLDMRMDNSQGQTAAQWLARAEIEDMAWVFKTYGEEKNARHIARCIAADRDKTPFLRTKDLADLIARITKSKERNKHPATRVFQAIRIYINSELDQIDQALEGAVNVLAPQGRLSVISFHSLEDRIVKRFIRRHSQGESVPHGFPVTEDQINKSRKLRAVGKAIMPSDEEIERNARARSSVLRIAERLDY
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_RICTY
Sequence: MTKIVRSKYKASRRLGVSLWGDSKDAFNTRNYRPGQHGQNTMIKTSDYGLHLKAKQRLKCYYGRVTEKQFRNTFALAQRMQGNTGENFIGLLESRLDTVVYRMNIAPTIFAARQLVSHGHIKLNGKKADIASIRLKEGDIIEIKESIQQIPLIQESIAKQGQTTPKYLSFDVSSLTGKYLRVPALSDVPYPFEAEVHLVIELYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MNMG_LISMO
Sequence: MQTYDAGTFDVIVVGAGHAGVEAGLASGRMGAKTLMLTINLDMVAFMPCNPSVGGPAKGVVVREIDALGGEMGRNTDKTYIQMRMLNTGKGPAVRALRAQADKWDYQHEMKHTIEKEENITLRQGLVDRLVIEDGVCKGVITNSGAIYYAKTVVITTGTFSRGEIIVGELRYSSGPNNQQPSVKLSEHLEELGFELRRFKTGTPPRVKSSTIDYSKTEEQPGDDHPRAFSFDTVEMLLDQLPCWLTYTNETTHEIIQANLHRSPMFTATKKGTGARYCPSIEDKIVRFSDKPRHQIFLEPEGKNTEEVYVQGLSTSLPEEVQREMLRTIPGLENVEMMRVGYAIEYDAVMPDQLWPSLETKLVEGLFTAGQINGTSGYEEAAGQGLMAGINAARKVFEKEPVILGRDQAYIGVLIDDLVTKGTEEPYRLLTSRAEYRLLLRHDNADLRLTEIGHEIGLISDERYERFLAKQSAIEAEKERLQKTRIKPTAEVQAMLKEIGSGELKDGILAADLLRRPEITYDKIAQIVSRETFVTDEIAEQVEIQIKYEGYIQKSNLQVEKMKRMEDKKIPENIDYDAISGLATEALEKLKKIEPLSIAQASRISGVNPADISILLVYIEQGKIAKISK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BST1_CRYNB
Sequence: MPAWPRFMSLRRQYLYKALDKNHQKHPIKHPHTRFLSRLFCALAVLFSYSIYQSFRTDLKQSGSWGCEMSWMSPSYRRLEWTEFISTRYALYLYREQGLDSEDTLSGHPVLFVPGNAGSYQQVRSIASSASKQYYEQVKARERNVVTGKKIDFFTADLKEEFSAFHARTVREQAVFIQHCIKGILQEYTHLPQEKRPTQVTLLAHSMGGVVARLAMDPITSISVDIIVTLSTPHILPPLALERDMDSIYSLIRWRRQHISTHPPLISICGGISDTQIVSDSCALPFFQAGNNSDIAVFTTGIPGVWTAVEHQAIIWCHQIRWRIARMLLDMSSRANTTAKLVTAKEWLLDYQEDETLKEPRSERQHDYSVSSRNMTFIGLHQPSKAFVAQQCNGLERCRTVPSVMSLLPFPNNPSDPFPLPGEGIKPSEVMLVAEISLSSTNTVVKINASQYGQTIAGSREHHLVKGNSWSEFTITMRYRYIRIQLLFCIRPTHTSTFSFYCGTLLTLPRQSWHLSGDISIALMSCTTGVAQKKLLQRTGQICDSVPYGRSCMASRVGCCGSSVSIIRFYQHRSVRTCKGFKLILVGEILSWNSALERIARRRMPICIVLLLLGATIQSQLPDFPMLHTFFLGVNQLEMVPLVGILGVWTFGLLCVVSFHLISTCAIFTTLLIPFKILHVAIWSRNIWTGSAALVSTDNNFYYAIPPALLVKCASCGGTIQKRHVCLKACRIALIILIMSSFSVGARWTWILSPIANAVLILFVASII
What is the function of this protein?
Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
What are the official names of this protein?
GPI inositol-deacylase.
What is the protein family that this protein belongs to?
Belongs to the GPI inositol-deacylase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y2888_MYCA9
Sequence: MSGHSKWATTKHQKAVKDARRGKEFAKLIKNIEVAARTGGGDPAGNPTLYDAIQKAKKTSVPNDNIERARKRGAGEEAGGADWQTIMYEGYGPNGVAVLIECLSDNRNRAAGEVRVAMTRNGGSMADPGSVSYLFSRKGVVTLEKNSLSEDDVLTAVLEAGAEEVNDLGETFEVISEPTDLVAVRQALQEAGIDYESAEASFQPSMSVPVDVETARKVFKLVDALEDSDDVQNVYTNVDLSDEVLAALDED
What are the official names of this protein?
Probable transcriptional regulatory protein MAB_2888c.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCR1_MACFA
Sequence: METPDTTENYDMITEFDYGDATPCHKVNERAILAQLLPPLYSLVFVIGVVGNLLVVLVLVQYKRLKNMTNIYLLNLAISDLLFLFTLPFLIYYKSTDDWIFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASSPLMYFSKTQWNIVRHSCNLHFPYESFQQWKLFQALKLNLFGLVLPLLVMIVCYTGIIKILLRRPNEKKSKAVRLIFVIMIIFFLFWTPYNLTELISVFQEFLFTHLCEQNRQLDLAMEVTEVIANMHCCVNPVIYAFAGERFRKYLRQLFHRRVAVHLVKWLPFLSGDRLERVSSTSPSTGEHELSAGL
What is the function of this protein?
Receptor for a C-C type chemokine.  Binds to MIP-1-alpha, RANTES, MCP-3 and, less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level.  Responsible for affecting stem cell proliferation (By similarity).
What are the official names of this protein?
C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIC_ALBFT
Sequence: MKVWSKRNVQRGNRKRWVGATGSLSARLAAAGQRFSVQVLSQGLQALDPDEASALGLSRLKVGYVREVLLRVDEVAVVFARSVTAHPHSQGPWRSIRGLGTRPLADVLFGQHGIARTPLQFASLQVASSLHRHVAHAWLGATGAALASRVLPARRSVFTRGAAPLLVMEVFAAPHAPWGWLTTKTRRGPPALPRTKP
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYLS_METBA
Sequence: MDKKPLDVLISATGLWMSRTGTLHKIKHHEVSRSKIYIEMACGDHLVVNNSRSCRTARAFRHHKYRKTCKRCRVSDEDINNFLTRSTESKNSVKVRVVSAPKVKKAMPKSVSRAPKPLENSVSAKASTNTSRSVPSPAKSTPNSSVPASAPAPSLTRSQLDRVEALLSPEDKISLNMAKPFRELEPELVTRRKNDFQRLYTNDREDYLGKLERDITKFFVDRGFLEIKSPILIPAEYVERMGINNDTELSKQIFRVDKNLCLRPMLAPTLYNYLRKLDRILPGPIKIFEVGPCYRKESDGKEHLEEFTMVNFCQMGSGCTRENLEALIKEFLDYLEIDFEIVGDSCMVYGDTLDIMHGDLELSSAVVGPVSLDREWGIDKPWIGAGFGLERLLKVMHGFKNIKRASRSESYYNGISTNL
What is the function of this protein?
Catalyzes the attachment of pyrrolysine to tRNA(Pyl).  Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
What are the official names of this protein?
Pyrrolysine--tRNA ligase, Pyrrolysine--tRNA(Pyl) ligase, Pyrrolysyl-tRNA synthetase, PylRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_TUPAK
Sequence: MRKYNPRKIKNKVNIPIVLHKANSTIPFVQGTVDYKNVALLRKYISAEGKILSRRLTRLTSKQQRHISTAIKTARIAGLLPFINQ
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HEM4_ORYSJ
Sequence: MALSSSSHLLPFSRPPATFPRARHAGGGRGRAGATGRFIACSSPPPPDVVVTRERGKNAKLIAALEKHNVQSLELPLIKHVEGPDTDRLSAVLRDEKFDWITITSPEAAAVFLEGWKAAGNPKVRIAVVGAGTERVFDEVIQYNDGSLEVAFSPSKAMGKFLASELPRTTETTCKVLYPASAKAGHEIQNGLSNRGFEVTRLNTYTTVSVQDVDPLILKPALSAPVVAVASPSALRAWLNLASQVDNWGNAIACIGETTASAAKKFGLKSIYYPTTPGLDGWVESILEALRAHGQSKEAPGC
What is the function of this protein?
Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III, a precursor of tetrapyrroles such as chlorophyll, heme and phycobilins.
What are the official names of this protein?
Uroporphyrinogen-III synthase, chloroplastic, Hydroxymethylbilane hydrolyase [cyclizing], Uroporphyrinogen-III cosynthase.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen-III synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GL1_ARATH
Sequence: MRIRRRDEKENQEYKKGLWTVEEDNILMDYVLNHGTGQWNRIVRKTGLKRCGKSCRLRWMNYLSPNVNKGNFTEQEEDLIIRLHKLLGNRWSLIAKRVPGRTDNQVKNYWNTHLSKKLVGDYSSAVKTTGEDDDSPPSLFITAATPSSCHHQQENIYENIAKSFNGVVSASYEDKPKQELAQKDVLMATTNDPSHYYGNNALWVHDDDFELSSLVMMNFASGDVEYCL
What is the function of this protein?
Transcription activator, when associated with BHLH2/EGL3/MYC146 or BHLH12/MYC1.  Involved in epidermal cell fate specification in leaves.  Together with TTG1 and GL3, promotes trichome formation and endoreplication.  Regulates the production of a signal that induces hair (trichome) precursor cells on leaf primordia to differentiate.  Binds to the WER-binding sites (WBS) promoter regions and activates the transcription of target genes (By similarity).
What are the official names of this protein?
Trichome differentiation protein GL1, Myb-related protein 0, AtMYB0, Protein GLABRA 1, Protein GLABROUS 1, R2R3-MYB transcription factor GL1.
What are the subcellular locations of this protein?
Nucleus. Note=Detected in trichome nucleus.
Protein: CRP_SALTY
Sequence: MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSSQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTHPDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR
What is the function of this protein?
A global transcription regulator.  Complexes with cyclic AMP (cAMP) which allosterically activates DNA binding to regulate transcription.  It can act as an activator, repressor, coactivator or corepressor.  Induces a severe bend in DNA.  Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.  Plays a major role in carbon catabolite repression (CCR) (By similarity).
What are the official names of this protein?
cAMP-activated global transcriptional regulator CRP, Catabolite activator protein, CAP, Catabolite gene activator, cAMP receptor protein, CRP, cAMP regulatory protein.