PharMolix/UniProtQA huggingface dataset:
Protein: SFH5_MAGO7
Sequence: MSEAEKKATIASGAEAAAPVAAQPPADSTAVVADASTIAVSTETAQEKAGKDETPAPIAAIAEPAASEAAAAPEESAPAAAAVVPKEPAAASEETKAPAAETAATPAPAAATSAAPEATKEKDAADAPAAAEKTGVAKLWEVCQAHEHKEIWGVTLQDPSSDVPTEIVLTKFLNANDGDVPKAVDQLTKTLDWRNKMKPLELLKKSFSRAKFGGLGYVTNHSEAADSKDPALKEVFTWNIYGNVKSMEETFGDLQQFIEWRVALMELALQELNIAGASAPHTITAENDPYKIYQVHDYKSISFLRQPASVKAASKETISVFSTVYPELLKEKFFVNVPVVMGFMYGLMKLFVAPKTLKKFHPMSDGGALAREFGGSKVKTLGDAMPKEYGGKGEELKATGKETMLD
What is the function of this protein?
Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity.  Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane.  Heme-binding protein that may play a role in organic oxidant-induced stress responses.
What are the official names of this protein?
Phosphatidylinositol transfer protein SFH5, PITP SFH5.
What is the protein family that this protein belongs to?
Belongs to the SFH5 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: DNAK_PSEA7
Sequence: MGKIIGIDLGTTNSCVAILENGNVKVIENAEGARTTPSIIAYTNDGETLVGQPAKRQAVTNPQNTLYAVKRLIGRRFEENVVQKDIQMVPYSIVKADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKAKGDHTVIVYDLGGGTFDVSVIEIAEVDGEHQFEVLATNGDTFLGGEDFDIRLIDYLVDEFKKESGINLKGDPLAMQRLKEAAEKAKIELSSTQQTDVNLPYVTADASGPKHLNVKVSRAKLESLVEDLVQRTIEPCRTALKDAGLDVSDIHEVILVGGQTRMPLVQKTVAEFFGKEARKDVNPDEAVAVGAAIQGAVLAGDVKDVLLLDVTPLTLGIETLGGVMTGLIEKNTTIPTKKSQVFSTADDNQGAVTIHVLQGERKQAAQNKSLGKFDLADIPPAPRGVPQIEVTFDIDANGILHVSAKDKATGKQQSIVIKASSGLSEDEIQQMVRDAEANAEEDRKFEELAAARNQGDALVHATRKMITEAGDKATAEDKATIEKALGELEVAVKGDDKAEIEAKMNALSQASAPLAQKMYAEQAQQGEGAAQGEQAKSADDVVDAEFEEVKDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CST_ARATH
Sequence: MGACISFFSSSSPSKTGLHSHATTNNHSNGTEFSSTTGATTNSSVGQQSQFSDISTGIISDSGKLLESPNLKVYNFLDLKTATKNFKPDSMLGQGGFGKVYRGWVDATTLAPSRVGSGMIVAIKRLNSESVQGFAEWRSEVNFLGMLSHRNLVKLLGYCREDKELLLVYEFMPKGSLESHLFRRNDPFPWDLRIKIVIGAARGLAFLHSLQREVIYRDFKASNILLDSNYDAKLSDFGLAKLGPADEKSHVTTRIMGTYGYAAPEYMATGHLYVKSDVFAFGVVLLEIMTGLTAHNTKRPRGQESLVDWLRPELSNKHRVKQIMDKGIKGQYTTKVATEMARITLSCIEPDPKNRPHMKEVVEVLEHIQGLNVVPNRSSTKQAVANSSRSSPHHYRYKAGALGAERKRATPGRFGSVEK
What is the function of this protein?
Acts as a spatial inhibitor of signaling that modulates abscission zone cell adhesion and expansion.  Acts both directly and indirectly by physically interacting with RLK5/HAE and SOBIR1/EVR at the cell surface.
What are the official names of this protein?
Probable serine/threonine-protein kinase CST, Protein CAST AWAY.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Nucleus. Note=Predominantly localized at the plasma membrane.
Protein: ZN711_DANRE
Sequence: MDQGGGILELHKDLKMPHTMIMPDFGMSGIAHLDGEHIVVSVPEAVMVSDVVTDEEGIMLETALEAEVVEEPDICQEDVITTEGVIMSESILGAEVAIQEALSGTADLIEETVPDQVFVAELMSPHIQSPLDHNLVSAEVMVTDADTVIDSHDTLQSDVTIKADDDVEDVKSTSEDYLMISLDEVGGKLDIEDTSLKISADVGQDDDGSKEDEFSSEVIKVYIFKADGDEDVEIGSTEVVEESDFPGRHTVMESVGSGRLPREKMVYMAVKDANQEDDLNCSEMTDQVYMEVIVGEEEAPAITEAQMEDSPVNKTIVPAAWATAYGSSLESKNGAATPYLQITDSISTSRALKQKIKKRRRGETRQCQTAVIIGPDGQPLTVYPCHICGKKFKSRGFLKRHMKNHPDHMFKKKYQCTDCEFTTNKKVSFHNHLESHKLIIKNEKIPEYTEYTRRYHEASPLSSNKLILRDKEPKLHKCKYCEYETAEQGLLNRHLLAVHSKNFAHVCVECAKGFRHPSELKKHMRTHTGEKPFHCQHCEFSCADQSNLKTHIKSKHGTDLPFKCGHCPQAFADDKELQRHAEIFQGHKTHQCPHCEHKSTNSSDLKRHIISVHTKDFPHKCDVCEKGFHRPSELKKHSETHKGNKVHQCRHCDFKTLDPFTLSRHILSVHTKDLPFKCKRCKRGFRHQNELKKHMKTHSGRKVYQCQYCEYNTTDASGFKRHVISIHTKDYPHRCDYCKKGFRRPSEKNQHIMRHHKETLL
What is the function of this protein?
Transcription regulator required for brain development.  Probably acts as a transcription factor that binds to the promoter of target genes, leading to activate their expression (By similarity).
What are the official names of this protein?
Zinc finger protein 711, Vitelline envelope protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MDM12_KOMPG
Sequence: MSLEVNWEQIASSEAIREQLVDWLNDQLKAVEVPKYLADIHVTSLSLGSKAPEITIRDIGKPFDDFYDIEEERAGTGEGDEDDGRVAPTSTPMKHQTSGSSDQTDASNPISPSTSHDHENDMQFVTEIKYDSDICVEVAAQLLMNYPAEKFISLPVRLKLSDLLIHTLAVVAYVNHRVFISLLCDISENEDTDNTESHSGNLRALSSKTASRIDVVKRLKVESELGSYEPDNGSILRSVGKIETFLVDTIRNLLVQEVGWPNWIEFQGV
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: ISPG_AKKM8
Sequence: MQSSYCPSPYRYTRRVTREVMVGNVGVGGSNPIRIQSMLTSDTRDTDACVKEALELAEAGCEIIRLTAQTKAYAANLENIARELRAAGCHVPLVADIHFKPDAAMEAAKWVEKIRINPGNFVDKKKFEVREYSDAEYREELDRLKEEFTPLVLFCREHGRAMRIGSNHGSLSDRILNRFGDTPEGMVESAIEFAQIARDLDYHSLVFSMKASNVKVMVAAYRLLVERMNALGPDWNYPIHLGVTEAGGGEDGRIKSAVGIGSLLTDGIGDTLRVSLTEDAVREVPVAYRLSNPFQPSERSDDPVSFPEPELSYDPLKFSKRQGGLAMYYGVRLGWEQPVRVAVPDAGFYALQTEREAMGDMMPELSLGQLDAIEVDPRCDADLEPLKELAEPSIVTVKNGLAMEPVYAFRLLAARIEDRHLILLKDTLVPGSVSGEDVPLTAARNIGSLLCDGIGDAVLIQGESDPRLASFLGFNILQATGTRLTRADYVSCPSCGRTLYNIQEATARIRKATEHLKGVKIAVMGCIVNGPGEMADADFGYVGGAPNKINLYVKHTPVKFNIPQEEAVERLVDLIKEYGRWVDPK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: LEU3_RUEPO
Sequence: MSNPSLLILPGDGIGPEVMAEVRKIIGWFGDKRGLNFDVSEDLVGGAAYDVHGVPLADETMAKAQEADAVLLGAVGGPKYDDLDFSVKPERGLLRLRKEMDLFSNLRPAQCFDALADFSSLKKDIVAGLDIMIVRELTSGVYFGEPRGIFEEGNERVGINTQRYTESEIERVARSAFELAMRRSKKLCSMEKANVMESGILWREVVTRVAKDYPEVELSHMYADNGAMQLVRAPKQFDVILTDNLFGDILSDCAAMLTGSLGMLPSASLGAPMANGRPKALYEPVHGSAPDIAGQGKANPIACILSFAMALRYSFDQGAEADRLEAAVEQVLADGVRTADLLGTEGVTPVSTTEMGAAILAKLDASL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_METCA
Sequence: MPQSTDLPAWRTLSEHFKTIAPRHMRDMFADDPGRFEAFSVRLGDLLFDYSKNRITRETVATLIQLAEEAGLREKIDAMFRGERLNVTENRAVLHVALRNRSNRPIRVDGKDVMPEVNRVLDRMRRFSQSVRTGEWRGATGKAITDVVNIGIGGSDLGPKMVVKALQPYADPRLRAHFVSNVDESDLVEILRPLNPETTLFVVASKTFTTQETMTNGRSARAWFLERISDESAIARHFVAISTNRNKVAEFGIDPRNMFEFWDWVGGRYSLWSAIGLPIALSVGMDRFEELLEGAHFVDEHFRTAPFERNIPVLMGLLGIWYINFFGAQSHAVLPYDQYLEDLPAHLQQADMESNGKTVDVEGRPVNYSTGPVIFGQPGTNGQHAFYQLLHQGSMLVPCDFLAAAESHHPLAEHHDILISNFLAQTEALMRGRTTDEARQEIASEELPPERLEALAAAKTFPGNKPTNSFLYRRLDPHTLGMLIALYEHKIFTQGVIWYINSFDQMGVELGKQLAKTILAELPGDAPVASHDASTNGLIRYFKSLR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_CERS4
Sequence: MFDDQDEIHPLLAGAPQTTEFRKLRKRIVREVREAIETYGMVERGARWLVCLSGGKDSYTLLAVLHELKWRGLLPVDLLACNLDQGQPGFPATVLPEFLSRMGVPHRIEYQDTYSIVMDKIPQGRTYCALCSRLRRGNLYRIAREEGCSAVVLGHHRDDILETFFMNLFHGGRLATMPPKLVNEDGDLFVYRPLAFVAEADCEKFARDMAYPIIPCDLCGSQEGLQRQQVKQILDGWEARSPGRRQVMFRALMNARPSHLLDPGLFDFLGLATAPRASEERQDEPPHLRGEA
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROCA_STAA9
Sequence: MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: DAPA_ECO55
Sequence: MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGIKEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_STRPM
Sequence: MTKEFHHVTVLLHETVDMLDIKPDGIYVDATLGGSGHSAYLLSKLGEEGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMKPKFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_PSYWF
Sequence: MNKHNKSADALSLYLVTDSALCADKGLIETVLAAIDGGVTLVQLRDKHASDEALYTTACELKEAIAGRVPLVINDKVQIAHKAKLDGAHIGQGDLSVKQARNILGHDAWLGLSINTLAQLQQTHHHHLDLLDYVGLGPVFATATKQDHAEPIGLEGLSTLSKASVLPTVAIGGINHANARQVYQTGCHGIAVVSAICAADDPKQAAELLIAQR
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PKN2_CLOPE
Sequence: MIGKILGNRYELLQCVGEGGMSFVYKARCRKLNRFVAVKILKDEFKNNEEIVRRFKKEATAIANLSNPNVVNVLDVGTQDDINYIVMEYVEGKTLKDIIKEKGALPYEVAISIGIKVAKALECAHKSGIIHRDVKPQNILVTEEGVVKVTDFGIAKSMDSSTIAHTNSVMGSAHYFSPEQAKGTYTDYRTDLYSLGIVLYEMVTGVVPFNGDSPVTVAVKHIQEKAIPPKNINQNIPNSLNDLIMKAMEKDPVNRYQTAKEIIGDLEKIKKDPNVTISSKSAEDEDQFTRVMSPVVVPNTETNNSEPDEDDEDDDEYYEDDEDEDEEENNIQTKPQKAINKNKKKSPILIIIATILVVALGITLGFLGMKKFMEGGKDVKIPNVVGEKVEDAKSKLEGLGLKVLEVTEESDQEKGIVLKVDPNVDSTVKTGSEVKLTVSGGEGQIKVPNFAEMNLDSVKRTLKSLGLELGSVDEEYSDSVPRGEVISQSPNANESVDKGSKVNVTISKGKEIKSETINIPDVSGKSVEEAKSILANAGVGVNPVKGEAAKSEGEAGKVYSQSQSGSLTIKQGEKVTITINYYGDYVKPEKPKHNAGELVGMTGAQAKAWASKNKINVSGITSDTAKVKSVSNSGEVEEGGSVSVTMEEEKKPEQPTQPNQPTQPTQPNQQAQPEQPKQPEQSGNN
What are the official names of this protein?
Probable serine/threonine-protein kinase CPE1738.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: URED_ACAM1
Sequence: MQQLEKQSDLASWHGRLSLTYEKKAHQTQVQQSYHQAPLNLQRPFYPEGPVCHSVMMHTAGGMVGGDRLSINVTLQPQTHALLTTTSAGKVYRSNGHGAQQTVQCQLDTNAILEWLPLGTIVFDQAQFRQTLQVELGPGAIFCGWDLTRFGRSARGERFMQGDWRSHTEIWQQGAPLWIDRQWLPGQPDIWESPHGLAGQPVVGSFLWVGQGVEPNLVQTARDLWQPTTDGAEMGVTRLPLGLVCRYRGPSSQAARQWFIQVWNLLRSTHLGRPACPPRVWPL
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35E2_MOUSE
Sequence: MSAAAKSQVPEEAAPGCEEEPKGKTLLTWGSLFGHRSEKIVFTKGDGSPEESLLTVTITETTVIESDLGVWSSRALIYLTLWFFFSFCTLFLNKYILSLLEGEPSMLGAVQMLSTTLIGCVKIFVPCCLYQHKTRLSYPPNFIMTMLFVGLMRFATVVLGLVSLKNVAVSFAETVKSSAPIFTVIMSRMILGEYTGLLVNLSLIPVMGGLALCTATEISFNILGFSAALSTNIMDCLQNVFSKKLLSGDKYRFSAPELQFYTSAAAVALLIPAWTFFMDIPVIGRSGKSFSYSQDIVLLLLTDGALFHLQSVTAYALMGKISPVTFSVASTVKHALSIWLSIIVFGNKITSLSAIGTILVTLGVLLYNKARQYQQETMQSLVTATSRNPEDDTEPLVPQDSRQHH
What is the function of this protein?
Putative transporter.
What are the official names of this protein?
Solute carrier family 35 member E2A.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. SLC35E subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HUTI_BRUSI
Sequence: MTKNSSTVFTHARIATLEEKAANLGLIEEAALVVKDARIVYAGPENKLPGEYASFEKIDCGNRLITPGLIDCHTHLVHAGNRAHEFELRLQGATYEEVARAGGGIVSSVRNLRAASEDDLVRETLPRLDALIAEGVTTVEVKSGYGLDRDSEIKSLKAARRLGEERDVAIRTTFLGAHALPPEMNGDKAAYIDRVINDMLPAIAEQGLADAVDGFCEGIAFLPDEIARVFDAAKAHDIPVKLHADQLSNLHGAALAASYGALSADHLEYTDADGAAAMASAGTVAVLLPGAYYFIRETQKPPVEAFRAAGTKMALATDNNPGTSPLTSLLLTMNMGATLFRMTVEECIAGVTREAARALGILDQTGTLEIGKDADLAIWDIERPAELVYRIGFNPLWKRVFKGQI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_HAEI8
Sequence: MKIALGIEYNGQNYYGWQRQEKVRSVQEELEKALSHIANEKIEIFCAGRTDSGVSGTGQVVHFETNAVRPEKAWAFGTNAHLPDDIAVAWAKQVDDEFHARFSATARRYRYILYCNKLRSAILAGGITHCHLDLDAEKMHQAGQCLLGEQDFSSFRAAQCQSHTPWRNVHHLNVSRIGKYIIVDIQANAFVHHMVRNIVGSLIEVGAGNQPIEWMQWLLEQKNRQLAAPTAKPDGLYLVDVIYPQKFDIPKRPIGPLFLEDGLLNRTLK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: REG1_PYRFU
Sequence: MPSIDEVDEIILRELSKNGRATLTELSRKVGLTPAAIKNRVEKLEKLGVIKGYSAIIDHSFLGEFLTALIEIELADPESDELSKLIRPILKLENIKDVYKKTGEFQLTIRATFRDVDSLNEFLKKIRRDYLKNMARRIKVSIILENFKEGGVTLL
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator PF0054.
Protein: RL31_PROMA
Sequence: MPKKDIHPNWYPDAKVICNGEVVMTTGSTQPEIHVDVWSGNHPFFTGTQKILDTEGRVDRFMRKYGMANPDEDSTKNTKSSKKETSEDSSSKGS
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL21_FERNB
Sequence: MYAIVENGGKQYKVEVGHLLHTEKMNGVAQGDKVVLDKVVLVKTDDGKVLVGKPYLTNVTITGIVVEHARARKILVGQFIPRKGHKTIKGHRQWYTTIKIENIEIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: YIDC_PHEZH
Sequence: MRDDNTRNTIIFFVCAALLLVLYQVFVIGPADKRRQAELARQAPPAAAAQAGQAGAPAAPQVPQAMTRQAAVAATPRVKIDTPMLTGSLSLRGARIDDLYLDRFRQTVEKDSPPVELLRPEGAQYPWFAEVGWVGANVPGLPDSGAVWTLAQGSTLAPGQPVVLTYANGQGLTFTRRIEVDDRYLFTITDTVANTTGQPVTIAPYGTVQRQGVPADLGKNQIVHEGAIGWLDGKLRQVKYGKWRKEGGGPAYNSTGGWLGITDKYWLAALIPGQQEAVTGQFRRTQAPGVDVLDANFVGAPVTIPAGRQVSETTRFFAGAKQVPILRDYEQSLGVAHFDNAVDWGNFWFLTRPIFQFLEFIHRYIGTFGLAILALTVVVRLIFFPLANKQYESITKMKKVQPQMEELRKKYKDDPAKQQQELLALYQREKVNPLAGCLPLLLQIPVFYALYKVLTVTIEMRHAPFMGWIQDLSARDPTTIWNLFGLIPWDPASAPLIGAFLNGPLHLGVLPILYGFTMWLTMAMSPPAGDPIQQKIFQLMPIIFTFIMAPFAVGLLIYWTWSNVLTLLQQYVIMRRFKVDNPIDQIIRKLTGKPKPAG
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BETB_PSEU2
Sequence: MARFELQKLYIDGGYVDASNPETFDAINPANGEVLAQIQRAGKDDVERAVVAAEKGQKIWAAMTAVERSRILRRAVDILRERNDELAALETLDTGKAISETRYVDIVTGADVLEYYAGLVPAIEGEQIPLRDSSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTSLTTLKLAEIYTEAGVPNGVFNVLTGSGREVGTWITEHPRIEKVSFTGGTDTGKKVMASASSSSLKEVTMELGGKSPLIVFDDADLDRAADIAMMANFYSSGQVCTNGTRVFVPNALKAEFEAKILERVKRIRAGNPEDENINFGPLVSFEHMESVLGYIAKGKEQGARLLCGGDRLTGGVFDKGAFVAPTVFTDCTDEMTIVREEIFGPVMSILGYDTEDEVVRRANDTDFGLAAGIVTRDLNRAHRVIHLLEAGICWINAWGESAAQMPVGGYKQSGVGRENGISSLAQYTRIKSVQIELGDYASVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: TUBZ_BACAN
Sequence: MAGNFSEIESQGNISLKFGFLGLGMGGCAIAAECANKETQIKNNKYPYRAILVNTNSQDFNKIEIKNAGNVRKIQLEGYEQGAARNPQVGEEAFVKHETKIFETVKQEFEDRDFIWITCGLGGGTGTGALLKAIEMLYEHDYNFGLLLTLPRDAEALKVLENATSRIRSIAMNQEAFGSIVLIDNAKLYRKFEEENPSALANEYTSYSNKYIADALHEINLVTSSFTPFSDTHFDASEFAQVINTPGVLSLAKLELKSNQLDTENPLGYLTQLGNALEKGVLYDTEREELESAKKSALSIVTSPLRASRLYNFSFLNQMENFLKDRTPYVDERPIAPYVNKHTAKKEEDIVKFYSVVAGLPLPKRVSDIIDEITRIKEEREQANSKKSNAVLNKLFAFDDSVQEEKPKKKKLNFGAEPEAEVADDSQPTKKKLSF
What is the function of this protein?
A tubulin-like, filament forming GTPase; the motor component of the type III plasmid partition system which ensures correct segregation of the pXO1 plasmid.  Essential for plasmid replication (PubMed:16585744).  The filaments seed from a DNA centromere-like site (tubC)-TubR complex which extends to surround the TubZ filaments.  Highly dynamic filaments grow at the plus end and depolymerize at the minus end, a process called treadmilling.  TubR-tubC complexes track the depolymerizing minus end of the filament, probably pulling plasmid within the cell (By similarity).  Has a high GTPase activity; in the presence of GTP assembles into dynamic filaments which bind almost exclusively GDP.  Filament formation is cooperative, requiring a critical concentration.  Formation occurs very quickly and is followed by disassembly as GTP is consumed.  Small amounts of GTP-gamma-S stabilize filaments (PubMed:18198178, PubMed:18179418).  Has high GTP and dGTPase activity, 6-fold lower ATPase activity.  Forms filaments in the presence of ATP that also disassemble.  Weakly binds DNA in a GTP-dependent, non-sequence-specific manner; GTP hydrolysis is not required for DNA-binding (PubMed:18179418).
What are the official names of this protein?
Tubulin-like protein TubZ, FtsZ-like protein TubZ-Ba, FtsZ/tubulin-like protein TubZ, Plasmid replication protein RepX.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family. TubZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Forms long, dynamic filaments.
Protein: SADH_MYCTU
Sequence: MSSFEGKVAVITGAGSGIGRALALNLSEKRAKLALSDVDTDGLAKTVRLAQALGAQVKSDRLDVAEREAVLAHADAVVAHFGTVHQVYNNAGIAYNGNVDKSEFKDIERIIDVDFWGVVNGTKAFLPHVIASGDGHIVNISSLFGLIAVPGQSAYNAAKFAVRGFTEALRQEMLVARHPVKVTCVHPGGIKTAVARNATVADGEDQQTFAEFFDRRLALHSPEMAAKTIVNGVAKGQARVVVGLEAKAVDVLARIMGSSYQRLVAAGVAKFFPWAK
What is the function of this protein?
Required for maintaining the appropriate mycolic acid composition and permeability of the envelope on its exposure to acidic pH.
What are the official names of this protein?
Putative oxidoreductase SadH.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.