PharMolix/UniProtQA huggingface dataset:
Protein: PACS1_MOUSE
Sequence: MAERGGAGGGPGGSGGGSSQRGSGVAQSPQQQPQQQPPQPQQPTPPKLAQATSSSSSTSAAAASSSSSSTSTSMAVAVASGSAPPGGPGPGRTPAPVQMNLYATWEVDRSSSSCVPRLFSLTLKKLVMLKEMDKDLNSVVIAVKLQGSKRILRSNEIILPASGLVETELQLTFSLQYPHFLKRDANKLQIMLQRRKRYKNRTILGYKTLAVGLINMAEVMQHPNEGALVLGLHSNVKDVSVPVAEIKIYSLSSQPIDHEGIKSKLSDRSPDIDNYSEEEEESFSSEQEGSDDPLHGQDLFYEDEDLRKVKKTRRKLTSTSAITRQPNIKQKFVALLKRFKVSDEVGFGLEHVSREQIREVEEDLDELYDSLEMYNPSDSGPEMEETESILSTPKPKLKPFFEGMSQSSSQTEIGSLNSKGSLGKDTTSPMELAALEKVKSTWIKNQDDSLTETDTLEITDQDMFGDVSTSLVVPEKVKTPMKSSKADLQGSASPSKVEGTHTPRQKRSTPLKERQLSKPLSERTNSSDSERSPDLGHSTQIPRKVVYDQLNQILVSDAALPENVILVNTTDWQGQYVAELLQDQRKPVVCTCSTVEVQAVLSALLTRIQRYCNCNSSMPRPVKVAAVGSQSYLSSILRFFVKSLASKTPDWLGYMRFLIIPLGSHPVAKYLGSVDSRYSSTFLDSAWRDLFSRSEPPVSEPLDVVGRVMQYVNGATTTHQLPVAEAMLTCRHKFPDEDSYQKFIPFIGVVKVGLVEDSPSTAGDGDDSPVVSLTVPSTSPPSSSGLSRDATATPPSSPSMSSALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFRSVQVSRLPHAGEAQLSGTMAMTVVTKEKNKKVPTIFLSKKPREKEVDSKSQVIEGISRLICSAKQQQTMLRVSIDGVEWSDIKFFQLAAQWPTHVKHFPVGLFSGSKTT
What is the function of this protein?
Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs.  Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits (By similarity).  Required for normal ER Ca2+ handling in lymphocytes.  Together with WDR37, it plays an essential role in lymphocyte development, quiescence and survival.  Required for stabilizing peripheral lymphocyte populations (PubMed:33630350).
What are the official names of this protein?
Phosphofurin acidic cluster sorting protein 1, PACS-1.
What is the protein family that this protein belongs to?
Belongs to the PACS family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Note=Localizes in the perinuclear region, probably the TGN.
Protein: MGRA_STAA8
Sequence: MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVLTILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKSETIRPELSNASDKVASASSLSQDEVKELNRLLGKVIHAFDETKEK
What is the function of this protein?
Regulatory protein involved in autolytic activity, multidrug resistance and virulence.  Controls autolysis by inactivating LytM, LytN (autolysins) and SarV (autolysis activator) and activating ArlRS, LrgAB and LytSR (autolysis inhibitors).  Acts as a dual regulator for resistance to multiple drugs by inactivating NorB and tet38 and activating NorA.  Positively controls the expression of virulence accessory gene regulator (agr) to promote alpha-hemolysin (hla) transcription and down-regulates staphylococcal accessory regulator (sarS), leading to repression of surface protein A (spa).  Binds directly to hla promoter to augment its activation.  Binds to sarS promoter to down-regulate spa expression.
What are the official names of this protein?
HTH-type transcriptional regulator MgrA, Regulator of autolytic activity.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_ACISJ
Sequence: MQKLVAIKGMNDILPPDSARWEWLEDKVRTLMARYAYRNIRTPIVEPTPLFVRGLGEVTDIVEKEMYSFEDRLNGEQLTLRPEATAGVVRAVVEHSMLYDGGKRLYYMGPMFRHERPQRGRYRQFHQIGAEALGFPGAEADAEIILLAHALWAELGLENVRLELNSLGQPDERRAHRAALIAYLEQHMDVLDEDARRRLHSNPLRILDTKNPAMQALVEGAPRLIDFLGEASLQHFETVKAILDANGVVWSLNPRLVRGMDYYNLTVFEFVTDQLGSQGTICGGGRYDYLIEQIGGKSAPAVGWALGVERVLELLKEQEAQVARPAADAYAVVPDASALPVVMATLQRLRAQGVSVQMHSSTAAGEGMGSMKSQFKKADASGARYALVFGADELARGAVTVKPLRDSGEQAERPLAALAEWAATLQSSR
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_EHRCR
Sequence: MDTVVKLNNIFSGLPKNKKSKVLGRGIGCGKGKTSGRGHKGQKARSGVSINGFEGGQQSIFTRLPKRGFNSLLKHRYSIVNLSTIQRLIDSKKIEDVSAITKEVLYNLGVISSIKEKIKILGNGKLNTAVAIEYDFISKSAESQVTLLSNVSASKE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YCIB_ACIF2
Sequence: MKLLTDFLPIILFFVAYRIHGIYTATEVLIVAAILLMAWQWWRRGRVETMTWVSTLLILTFGGLTLYFHNDTFIKIKPSILYVLFAAALLFTHWREEPLLQRLMGGQLPAALPLSFWRRLNGYWIAFFLFGAVLNLIVAYAFSTGIWVDFKLFGMLAITVIFVLFQAVVISRALPQEAKDGDSSA
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UREG_METSB
Sequence: MSETNGPFRIGIGGPVGSGKTALTDRLCKAMRERWNIAAITNDIYTKEDAEFLTRSAALAPERIMGVETGGCPHTAIREDASINLAAVDAMNARFPGLDLVFIESGGDNLAATFSPELADLTIYVIDVSAGDKIPRKGGPGITRSDLLVINKIDLAPLVEASLEVMDRDSRKMRGEKPFLFTNLKTNLGVAEIVAFIERQGGLSGV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_THET2
Sequence: MVVAGIDPGITHLGLGVVAVEGKGALKARLLHGEVVKTSPQEPAKERVGRIHARVLEVLHRFRPEAVAVEEQFFYRQNELAYKVGWALGAVLVAAFEAGVPVYAYGPMQVKQALAGHGHAAKEEVALMVRGILGLKEAPRPSHLADALAIALTHAFYARMGTAKPL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: Y105_RICPR
Sequence: MKTLKVLKIFIIVYISSVSLESFAGFGESCSNLPITSDGYLETYTAYGYIIRSIDMKDPRGNCNPSTSSITFCFKNVEGSASPCTIYTLNEGDTRKISDLSTDNNPDLGANTVLKNIVLTVKKFGNDLCLAMPTSRGPMPVACKSLSVTPTATKPKDENCNIGKSCYTGANYSQSLINFSGLAVQCLSETLNKIFFTGSSCSAQDQNSRITHLASFATFQGYLKRIIGAALILYTMFFAFNMALNKEYATTEKITLFIIKFLFVVYFSIGLGPLDFSGGQPVKENGMLKYGLPLLTGAAPDFAGMIFNAAGSRGLCQFDNTKYKDGYKFYGLWDAIDCRIGYYLGLDLLYNIDKNGILGRPVSNGTSGNNKPIPNFDPDGKKDRPHDLSKAGALRFFTVMFGFFMSGHVIILVAGMVFSVIFLSILLYFITHYLVCMVTIYVMTYISPIFIPMVLFTRTKAYFDGWLKVCISCALQPAVVAGFIALLITMYDSAIFKNCEFLRYDYEKGDIRFSTFELRLPSIDADKCQESFGYKMLKYYAGEGWEEHLLILFPIKSIVRDVVSILAELLCVLIFSVIFYYFSKSIGRFAADLTNGPNMDAVTASPTKIVDLVKKGAAFLKDASVHEHGKSSLGDKPDIGNKRKDGAQQGEDAVNSSGGEVADLASGSGGGK
What are the official names of this protein?
Uncharacterized protein RP105.
What is the protein family that this protein belongs to?
Belongs to the TrbL/VirB6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HA17C_CBCP
Sequence: MSSERTFLPNGNYKIKSLFSDSLYLTYSSGALSFSNTSSLDNQKWKLEYISSSNGFRFSNVAEPNKYLAYNDYGFIYLSSSSNNSLWNPIKIAINSYIICTLSIVNVTDYAWTIYDNNNNITDQPILNLPNFDINNSNQILKLEKL
What is the function of this protein?
The hemagglutinin (HA) component of the progenitor toxin protects the structural integrity of botulinum neurotoxin; may increase internalization of the neurotoxin into the bloodstream of the host (PubMed:9421908).  The HA component is involved in binding to the upper small intestine through interactions with glycolipids and glycoproteins containing sialic acid moieties (Probable).
What are the official names of this protein?
Hemagglutinin component HA-17 type C, ANTP17, HA 17 kDa subunit, HA2.
What are the subcellular locations of this protein?
Secreted.
Protein: LIVB3_BRUSU
Sequence: MNLKLLSSLAFAATIGFASAAYADITIGVIAPLTGPVAAFGDQVKKGAETAVEVINKAGGIKGEKVVLKFADDAGEPKQGVSAANQIVGDGIKFVVGPVTTGVAVPVSDVLSENGVLMVTPTATGPDLTARGLENVFRTCGRDDQQAEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKGGITEVHYDSVTPGDKDFSALVTKLKSAGAEVVYFGGYHAEGGLLSRQLHDAGMQALVLGGEGLSNTEYWAIGGTNAQGTLFTNAKDATKNPAAKDAIQALKAKNIPAEAFTMNAYAAVEVIKAGIERAGSTDDSAAVAKALHDGKPIETAIGTLTYSETGDLSSPSFDIFKWDDGKIVGLE
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: APAH_PASMU
Sequence: MATYLVGDLQGCYDELQRLLEKVQFDSTQDQLYLVGDLVARGDKSLECLRFVKSLGKSAKTVLGNHDLHLISTALGIKKVKVRDRVDAIFHAPDFEELIDWLRHQPLLVHNEQQNFLMTHAGISPDWDLATAKQCAHEVENVLRHGDYHNLIENMYENRPDRWHDDLQGLDRLRYSINVFTRMRFCYWDHRLDFDCKLPPESAPEELTPWFNLANPLYQTIPIVFGHWASLVNTTTPNNIYALDTGCVWGNRMTMLRWEDKQYFSQHAVKNYRDF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: CAPP_MYCA1
Sequence: MVEASEGTLEPIGAVQRTLVGREATEPMRADIGLLGAILGDTVREQNGQQVFELVERARVESFRVRRSEIDRAELARMFAGIDIHQAIPVIRAFSHFALLANVAEDIHRERRRAIHVAAGEPPQDSSLAATYAKLDRAQLDSATVAEALRGAVVSPVITAHPTETRRRTVFVTQHRITELMRLHAEGHIETDDGRNIELELRRQVLTLWQTALIRLSRLQITDEIEVGLRYYAAAFFKVIPRVNAEVRNALRARWPGADLLDEPIVAPGSWIGGDRDGNPNVTADVVRRATGDAAYTALAHYLAELTACEQELSMSARLVAVTPELAALAEDCAEKARADEPYRRALRVIRGRLTATAAEILDRRPQHELDLGLPPYATPAELRGDLDTVDASLRAHGSALLADDRLALLREGVRVFGFHLCGLDMRQNSDVHEEVVAELLAWAGVHPDYRSLPEDERVELLAAELGTRRPLVGDRAELSELADKELGVVRAAAHAIRRYGPAAVPNYVISMCRSVSDVLEAAILLKEAGLIDASGPEPYCPVGISPLFETIEDLHNGAAILHAMLELPLYRALVAARGQSQEVMLGYSDSNKDGGYLASSWAVYRAELALVEVARKTGIRLRLFHGRGGTVGRGGGPSYEAILAQPPGAVNGSLRLTEQGEVIAAKYAEPQVAQRNLESLVAATLESTLLDVEGLGDTAEPAYAVLDEVAVLAQRAYAELVHETPGFVDYFMASTPVSEIGSLNIGSRPTSRKPTESIADLRAIPWVLAWSQSRVMLPGWYGTGSAFEQWIAAGPQSRAERVDILHDLYRRWPFFRSVLSNLAQVLAKSDLGLAAQYAELVDDAALRRRVFGKIADEHRRTIAMHKLITGQDNLLADNPALARSVFNRFPYLEPLNHLQVELLRRYRSGDDDELVQRGILLTMNGLTSALRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: AROE_PROA2
Sequence: MCSITSILGLIGRNVNYSYSPFIHNTAAEMLRLPFYYTIFNIADARQIPDALNGMRALGIAGLNVTIPYKQVVTEYVDTLSAEAQAVGAVNTIVNNNGRLSGCNTDIAGVSHPLKPYKERLHQSPAGIFGNGGAALAAVEALRRDYHPSAIRLFVRDPDKGLALAEQVHAKHPEAPIEIFKIDAYDAIRDCHLLINATPIGTKGVQTAGNSALLPQEQKLLHDGQIIFDMVYNPLRTPFVNMAAEAGAVVIPGVEMLIAQAAESFCLWTGETMPVDSIREKILKKLTAQP
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: VP18_NPVAC
Sequence: MATSKTIVLYLCQAPATASLYVSADTDADEPIIYFENITECLTDDQCDKFTYFAELKQEQALFMKKVYKHLVLKNEGAFNKHHVLFDAMIMYKTYVHLVDESAFGSNVINYCEQFITAIFEIFTLSSKIVVAVPVNWENDNLSVLLKHLHNLNLIGIEIVN
What are the official names of this protein?
P18 protein.
Protein: TRPF_STAHJ
Sequence: MILKFCGIKTKVEALSIRPLNINMVGFIHYPKSKRHLDIEQINKLSRLLPDEIDRVVVLVNPTLQLIKKIINATNINAIQLHGDETIDFIKQLRLNFKNIKIIKALPATQNIINDINQFKEHIDLFIIDTPSEQYGGTGQSFDWTLLKGLDQSIPFLIAGGIDVDKIKQIETLKLNHLGYDISSSIETDGMKDKNKMLTVIQQVKGEL
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: RBL_METMA
Sequence: MRRDYIDIGYSPKETDLVCEFHIEPTAGVNFEEAATHLAGESSIDSWTEIATLSPELAEKLKPHVFYADEGAQTVRVAYSEELFELGSVPQVLSAVAGNILSMKIVDNVRLQDIAFPKSMINEFKGPNFGLPGIRKLVGVQDRPLIGTIVKPKVGLNSEKHAEVAYNSFVGGCDLVKDDENLSDQKFNSFEKRAELTLKLAEKAESETGEKKMYLCNVTAPTCREMIRRMNFLKDLGASYVMVDIVPAGWTAIQTLREEAEDAGLALHAHRCMHSAYTRNPRHGISMLVVAKLCRLIGLDQLHIGTVVGKMHGEKHEVLNLRDQCVLDKVPADESQHILAQDWRGLKPMFPVASGGLAPTMIPDLYSIFGKDVIMQFGGGIHAHPMGTVAGATACRQALEASLEGISLQDYAKNHKELETALGKWLKK
What is the function of this protein?
Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA).  Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase.
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type III subfamily.
Protein: G3P2_DROPS
Sequence: MSKIGINGFGRIGRLVLRAAIDKGASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYVVESTGVFTTIEKASTHLKGGAKKVVISAPSADAPMFVCGVNLDAYKPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPAATGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGASYDEIKAKVQEAANGPLKGILGYTDEEVVSTDFLSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKD
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 2, Glyceraldehyde-3-phosphate dehydrogenase II, GAPDH II.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_RICPU
Sequence: MSITTERKQKLIKEYAITENDTGSSAVQCAILTERINNLTEHFKSNHKDHTSRRGLLILVGRRRRLLNYIKKNNVSKYLDLISKLGIRKIK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TEG5_BHV1C
Sequence: MDAARDGRPERRRAVSGTYRTHPFQRPSARRSAGRPARCGRRGRGAPRVRRPRPYFQRPPDEDTSEDENVYDYIDGDSSDSADDYDSDYFTANRGPNHGAGDAMDTDAPPERAPEGGAPQDYLTAHLRAIEVLPESAPHRSLLERTARTVYAQQFPPRDLSAGSKAPAQRARRSLRGFPRGGGGGQEPGPDDEGDDAADLREDLVPDEAYAHLERDERLSEGPPLLNMEAAAAAAGERSVVEELFTYAPAQPQVEVPLPRILEGRVRPSAFFAQMSLDALCRTPPNDQRVARERRAWEMAGTPHGLLITTWSTVDPEFSIGGMYVGAPEGTRPRLVWRRAMKQAMALQYRLGVGGLCRAVDGAACRPLRRCSFWRDALLRECATAIFCRGRGARAAPRRLPRPAVGLLAATQFTPPDASPHATLFRGSMGSLIYWHELRVMLTAVPALCARYAGAGLQSAELYLLALRHSEAPGYTANERYALSAYLTLFVALAERGLRWLYLAGAHLLGPHPTAAAFREVRAKIPYERLPLGSATLHDAEVETVDSATFQEALAFSALAHVYGEAYVAVRTATTLLMAEYAVHAERRDVRQMTAAFLGVGLIAQRLMGSLNLLLNCVAGAAVYGGRRVTVREGTLARYSLLADAALPLVRPVFLVEFREARDGVMRELRLRPVASPPLAGKRRVMELYLSLDSIEALVGREPLGSRPVLGPLVDIAEALADHPHLVTGDGRGPRLGGR
What is the function of this protein?
Tegument protein that can bind to various RNA transcripts.  Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase UL41/VHS.  Also plays a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins UL31 and UL34.
What are the official names of this protein?
Tegument protein UL47.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL47 family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Host cytoplasm. Note=Major tegument protein of the virion. Undergoes nucleocytoplasmic shuttling during infection. Localizes to the major sites of transcription in the infected cell nucleus.
Protein: PCKG_SALTO
Sequence: MVAPATVRGIDQAPTSHPKLLAWVREIAELTTPDRVVWADGSEEEWRRITDELVEAGTLVRLNPEKKRNSFYARTDPTDVARVEERTFICSVDEADAGPTNNWMAPAEMKRTMTELYRGCMRGRTMYVIPFCMGPVEAKNPMFGIEITDSPYVVASMRIMTRMGTKILEAMGDDADFVHALHSIGAPLAPGQQDVSWPCNETKYISHFPETREIWSYGSGYGGNSLLGKKCYSLRIASVMGRDEGWLAEHMLILKITSPEGRAYHIAGAFPSACGKTNLAMLEPTIPGWKVETVGDDIAWMRFGPDGRLYAVNPEYGLFGVAPGTDWKTNANAMRTLDRGNSIFTNVALTDDGDIWWEGMGEPPTHLIDWKGNDWTPQSEHLSSHANSRFCTPITQCPILAEDYYDPNGVPIDAILFGGRRRDTVPLVTEARDWVHGVYLGATLSSETTAAASGAVGVVRRDPMAMLPFIGYNAGDYFRHWIEMGKGTDGDESKLPSVYYVNWFRKDAEGSFLWPGFGENSRVLKWIVERLEGRAEAVETPIGMVPAEDALDVEGLDMTSEDIRIALKVDVNEWQAELPLVTEWFEKFGDKLPGVLWAELDALRARLDAEPQ
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREB1_MOUSE
Sequence: MGNSYAGQLKSTRFEEVLHNSIEASLRSNTLVPRPIFSQLYLEAEQQLSSLEGGSRADNEEEEEDGEGGLEPSSPPNAYQLPPPPEGCCTTDGFCQAGKDLRLVSISSEPIEVPAGFLLVGAKSPSLPDHLLVCAVDKRFLPDDNGHNALLGFSGNCVGCGKKGFCYFTEFSNHINLKLTTQPKKQKHLKYYLVRNAQGALTKGPLICWKGSEFRGRQNSTNTCSSSLFPPLESSGSLAAFPTEPVPGTNPSVPVGAQQAGPASDHPSVTTATGPAVFNGKDSPKHPQLVKSSLSALPRPSALGILPNSGPPKKRHKGWSPESKSTTDGGFIQGGGNRAKHEGTSIPCVPQAGLVGPASVTFPVVASGEPVSVPDNLLKICKAKPVIFKGHGNFPYLCGNLNDVVVSPLLYTCYQNSQSLARAYEQHGASTMQPISEETQLLLTVYYLVQLAADQVPLMEDLEQIFLRSWRESHLTEIRQYQQAPPQPFPPATSTAAPVTSAQLPWLAGLAASSCNDSVHVIECAYSLAEGLSEMFRLLIEGKLSKTNYVVIICACRNAAIDSCIAVTGKYQARILSESLLSPAEYQREVHYELVTGKVDSLGTFFSSLCPEGDIDILLDKFHQENQGHVSSSFTASSTKKTAVLDASGVPVCTSYHQEPRGVRPFQLAVAQKLLSHVCSIADSSTQNLDLGSFEKVDFLICIPPSEVTYQQTVFHVWHSGVLLELGLEKEPVTKQRAEQHVLKLDTEAQARFKAFLQNSFQNPHTLFVLIHDHAHWDLVSSAVHNIYSQSDPSVGLVDRLLNCREVKEAPNIVTLHVTSFPYALQTQHTLISPYNEIHWPISFSNGVDLYHESKKYFGLSEFIDSTLSGHSLPLLRYDSSFEAMVTALGKRFPRLHSAVIRTFVLVQHYAAAMMAVSGLPQMKNHTSVETLEITQNLLNSPKQCPCGHGLMVLLRVPCSPLAAVAYERLAHVRARLALEEHFEIILGHPSSGITVGKHFVKQLKMWQKIEDAEWRPQTYLELEGLPCILIFSGMDPHGESLPRSLRYCDLRLINSSCLVRTALEQELGLAAYFVSNDIPLEKGPKNEALESDGEKLSSTDEDEEAGTEGCFEAGSTSEQRGPVKRERSHSHDSASSSLSSRASGSVLYGESLAQPSGPPQGELTRSPPSCGPAEEGRAPGEIQRLRVSQGSTVISRHSPGLVPQPDSSLRTGRRSLQVPAAPSSQLSSSSGSSSTCAVPTANVLVLQASQCSMAKACRQPPIVFLPKLVYDMLLSTDSSGLPKSASLLPSPSVMWTSSFRPLLSKMMTSTEQSLYYRQWTVPRPSHMDYGNRAEGRVDSFHPRRLLLSGPPQIGKTGAYLQFLSILSRMLIRLTEVDVYDEEEINTSFREESEWRYLQLADPWPDLELFQKMPFDYIIHDPKYEDASLICSHPQTIKSEDRGMSRKPEDLYVRRQTARMRLSKYAAYNTYHHCEQCQQYMGFHPHYQLSESTLHVFAFSCSMLGEEVQLHFIIPKSKEHHFVFSQPGGQLESMRLPLVTDKSHEHIKSPTFTPTTGRHEHGLFNLYHAMDGANHLHVLVVKEYEMAIYKKYWPNHIMLVLPSIFNSAGVGAAHFLIKELCYHNLELERNRQEELGVKPQDVWPFIVIADDSCVMWNVADVDCAGERSREFSWSERNVSLKYIMLHIEASPNITHYALLGMRKWASKTRGREVQEPFSRCHVHDFIILNVDLTQNVQYNQNRFTCDDVDFNLRVHSAGLLLCRFNRFSVMKKQIAVGGHRSFHITSKVSDSSVAIVPSQYICAPDSKHTFLAAPAQLLLEKFLQYHSHRFFPLSLKNHSHPVLSVDCYLNLGPQISVCYVSSRPHSLNISCSDMVFSGLLLYLCDSFVGASFLKKFHFLKGATLCVICQDRNSLRQTVVRLELEDEWQFRLRDEFQTANAKEDRPLFFLTARHI
What is the function of this protein?
May play a role in estrogen-stimulated cell proliferation.
What are the official names of this protein?
Protein GREB1.
What is the protein family that this protein belongs to?
Belongs to the GREB1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SP2AB_BACC1
Sequence: MRNEMNLQFSALSQNESFARVTVAAFIAQLDPTMEELTEIKTVVSEAVTNAIIHGYEGNAEGVVYISVILEEAMVKLTIRDEGIGIFNLDEARQPLFTTKPELERSGMGFTIMENFMDEVEVISNESFGTTIHLTKYLSNSNALCN
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: DENR_ASPCL
Sequence: MGEIAQPAFFESKLKQIVYCGVCTLPPEYCEFGGTAKKCEEWLKDNHEETYQRLYSEEALSSNLSTLSVSVRERAAKDAAKKEAKAALAEARDAERKAAAKVQIKRVERNKRKHVTVITGLEVHGLENKKVAKELGKKFATGSSVTKSPAGVEEITVQGDVSEDVQEWLLEVYGKELPESNIELVEDKKKKSSS
What are the official names of this protein?
Translation machinery-associated protein 22.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_CUPMC
Sequence: MTARTLLVMAGGTGGHVFPGLAVARALRDEGWRVVWLGNRTGMEATLVPKHDIPMEYIQFGGLRGKGLLTKLLLPLNLLRAFWQSIGALRRVKPDVVLGMGGYITFPAGMMASLLGRPLVLHEQNSIAGLANKVLAKVADRVLCAFPDALPNSEWTGNPVRAELAQIPAPESRYDHRAGPLHVLVVGGSLGAAALNDVVPKAIALLPEGQRPVVKHQAGAKQIDTLRANYAAAGVAGDTVPFIDDMAAAYADADLVICRAGAMTVSEVAAAGVAALFVPFPHAVDDHQTTNATFLSKQGAALLVQQNELTAEGLAKTLAGLSRTQLKDMARAARGLAKPEATRRVAEICSQLAGKS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYR_HELAH
Sequence: MHTLIKSVLEEILEAEVIIEHPKDREHGHYATPIAFNLAKIFKKSPLVIAEELALKISTHAKTQGFFDSVVACKGYINFTLSLDFLERFTQKALELKEKFGSKFKSENSQKIFLEFVSANPTGPLHIGHARGAVFGDSLAKIARFLGHEVLCEYYVNDMGSQIRLLGLSVWLAYREHVLKEGVTYPEVFYKGEYIIEIAKKAHNDLEPSLFKENEETIIEVLSSYAKDLMLLEIKDNLDSLGIHFDSYASEKEIFKHKDAVFKNLEKANALYEKDSKIWLKSSLYQDESDRVLVKEDKNYTYLAGDIVYHNEKFKQNYTKYINIWGADHHGYIARVKASLKFLGYDSNKLEVLLAQMVGLLKDNEPYKMSKRAGNFILIKDVVDDIGKDALRFIFLSKRLDTHLEFDVNTLKKQDSSNPIYYIHYANSRIHTMLEKSPFSKEEILQTPLKNLNAEEKYLLFSALSLPKIIEASFEEYGLQKMCEYAKTLASEFHRFYNAGKILDTPKTKELLKICLMVSLSLTNAFKLLGIEIKTKISAKD
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR3_RAT
Sequence: MGTAKVTPSLVFAVTVATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPREGLLTTLWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLINRKEEDQATEILQRLWGTPDVIQEIQEMKDESIRMSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDEYEAMSFVCIVAILVYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVFFLIFTSFKVPETKGRTFEDITRAFEGQAHSGKGSAGVELNSMQPVKETPGNA
What is the function of this protein?
Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane.  Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate.  Does not mediate fructose transport.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 3, Glucose transporter type 3, brain, GLUT-3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Perikaryon. Cell projection. Note=Localized to densely spaced patches along neuronal processes.