PharMolix/UniProtQA huggingface dataset:
Protein: ATP6_GEOKA
Sequence: MEHKAPLVEFLGLTFNLSDMLMITITSLIVFIIAVAATRSLQLRPTGMQNFMEWVFDFVRGIINSTMDWQTGGRFLTLGVTLIMYVFVANMLGLPFSVHVNGELWWKSPTADATVTLTLAVMVVGLTHYYGVKMKGASDYLRDYTRPVAWLFPLKIIEEFANTLTLGLRLFGNIYAGEILLGLLASLGTHYGVLGAVGAAIPMMVWQAFSIFVGTIQAFIFTMLTMVYMAHKVSHDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_CORGL
Sequence: MSNTENKQKRVSVGKDIATRRRVARARRHFRIRKNLRGTPEAPRLVVHRSSRHMHVQIIDDVAGHTLAAASSIEAEVRATEGDKKAKGAKVGQLIAERAKAAGIEQVVFDRAGYKYHGRVAALADAAREGGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HIS7_SYMTH
Sequence: MTDCSRNETGALAERVGQVARKTRETDIAVTWRLDGAGRADVDTGVPFFDHMLDQIARHSLTDLTARAVGDLEIDAHHTVEDTGIALGQALRRALGDGRSIRRYGSAFVPFDETLAFAAVDVSGRPYLVFDAALPAQKVGNFDTELAEEFFRALAMNAGITLHLKVHYGRNTHHMIEGLFKAFARALGDAVARDPRVLGVPSTKGALF
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDDP_ROSNI
Sequence: MNQHYSETRKIDPSRGATLGDNTPNDNNRIEIGPTQLAFGEWATAGLALPDLQRMREFRWNRLTQAVVDRDYGGVLMFDPLNIRYATDSTNMQLWNAHNPFRALLVCADGYMVIWDYKNSPFLSTFNPLVREQRFGADLFYFDRGDKVDVAADAFSNEVRTLIAEHGGGNMRLAVDKIMLHGLRALEAQGFEIMEGEELTEKTRAIKGPDEILAMRCAVHACETSVAAMEHFAREAVPQGNTSEDDVWAVLHAENIKRGGEWIETRLLASGPRTNPWFQECGPRIIQNNEIISFDTDLIGSYGICVDISRSWWVGDAAPPADMVYAMQHAHEHIMTNMEMLKPGVTIPELSERSHRLDEQFQAQKYGCLMHGVGLCDEWPLVAYPDQAVPGSYDYPLEPGMVLCVEAAVGAVGGNFTIKLEDQVLITETGYENLTSYPFDPALMGR
What is the function of this protein?
Able to cleave dimethylsulfonioproprionate (DMSP), releasing dimethyl sulfide (DMS).  DMS is the principal form by which sulfur is transported from oceans to the atmosphere (PubMed:19220400, PubMed:20378650).  The real activity of the protein is however subject to debate and it is unclear whether it constitutes a real dimethylsulfonioproprionate lyase in vivo: the low activity with DMSP as substrate suggests that DMSP is not its native substrate (PubMed:25140443).
What are the official names of this protein?
Dimethylsulfonioproprionate lyase DddP, DMSP lyase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: RF3_YERPS
Sequence: MSPSEYALEVAKRRTFAIISHPDAGKTTITEKVLLFGHAIQTAGTVKGRGSSHHAKSDWMEMEKQRGISITTSVMQFPYGGCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDREIRDPMEVLDEVERELNIACSPITWPIGCGKSFKGVYHLHKDETYLYQSGKGHTIQEVRIVKGLNNPDLDVAVGEDLAKQFRQELELVQGASHEFDHEAFLSGDLTPVFFGTALGNFGVDHMLDGLVEWAPAPMPRKTDTRVVVASEEKFTGFVFKIQANMDPKHRDRVAFMRVVSGRFEKGMKLRQVRTKKDVVISDALTFMAGDRSHVEEAYAGDIIGLHNHGTIQIGDTFTQGEDMKFTGIPNFAPELFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLSNNDLIVGAVGVLQFEVVSSRLKSEYNVEAVYESVNVSTARWVECNDVKKFEEFKRKNELNLALDGGDNLSYIAPTMVNLNITQERYPDVIFRKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CICC_EMENI
Sequence: MALRYLNKFSLLSLAVPTLAAPIGSSFGVPGTDALYDYVVVGAGNAGAPVAYRLAETGHTVALVEAGSLYEYGNGNLSQIPANSLFFIGKDPEWTNNLVDWNFVTSPQAEWNNASVHYASGKVLGGSTGRNLMTYHLPTKGSLDRWAEDVSDESWNFDNMLPYIMKSQRFTPPNNNLRFRNATPTYDPAVLGRRGRLDVTYPNYANGLASWLVRGFRDIGLAAIRGLNGGQLIGSAYTLSTIQPGNQHRASSKTAYLDPLIGRNLNLIIYQSTHAKRILFSNDTVATGVRVSSEGQEYTLSARNEVIVSAGAFKTPQLLMVSGIGPAANLERYGIPLVADRPGVGQNLQDHTLAGPSYRVNAITGSSNSIPEFITEAQRQYNSNPPRGVLTNTGVDILGWEKVPEQLRGNFSTETEDALASLPEDWPELEYLPVYGYFGDQNNYMVTPNDGFNYLTIAAAVVSPLSRGTVDIASNDTEVNPIIDPRWFAHPGDIQVAVAGFRRSRALMASPAMAGITLGGESYPGTDVQTDDEIVEWLREASNTVHHACCTAGMGPRDNPDSVVDTQGRVIGVSGLRIVDASIMPFLPPGHPISIIYGLAERIAESILADA
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of cichorine, a phytotoxin active against knapweed, corn, and soybeans (PubMed:24244835).  The first step in the pathway is performed by the non-reducing polyketide synthase pkbA that condenses one acetyl-CoA starter unit with 3 malonyl-CoA units (PubMed:22510154).  PkbA also catalyzes one methylation step to produce 3-methylorsellinate (PubMed:22510154).  The nonribosomal peptide synthase-like protein cicB, the cytochrome P450 monooxygenase cicH and the O-methyltransferase cicE are involved in the conversion of 3-methylorsellinate into nidulol (PubMed:24244835).  CicB converts 3-methylorsellinate to a yet unidentified intermediate, cicH may play a ring-closing role for cichorine and cicE is plausibly responsible for the methylation of one of the phenol groups (Probable).  The oxidoreductase cicC acts downstream with still unidentified enzymes to further convert nidulol into cichorine (PubMed:24244835).
What are the official names of this protein?
Oxidoreductase cicC, Cichorine biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: RPOC_MAGMM
Sequence: MTPVSDAPATPSSEISAAGQSVFKLFSRPMLGQSFDGIRISIASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVVCEKCGVEVIQSKVRRERMGHIELAAPVAHIWFLKSLPSRIGLLLDMTLKDLERVLYFENFVVLESGMTPMKRGELLTEDRYYQLIEEFGDEFRAGIGAEAIREMLVDLKIPEEINQLRDELRDTSSEARRKKIVKRLHTLEAFQDSKNSPEWMILEVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLFELKAPDIIIRNEKRMLQESVDALFDNGRRGRVITGTNKRPLKSLSEMLKGKQGRFRLNLLGKRVDYSGRSVIVVGPELKLHECGLPKKMALELFKPFIYNRLEERGLATTIKAAKRMVEKEKGEVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPKLVEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQIEARVLMMSTNNILSPANGKPIIVPTQDIILGLYYMTSERANVAGEGMIFSNTMEVKQAFDAGVANLHASIQCRFRGKRVHTTVGRMLLADMLPERIDFQAINKLITKKEVTKLIDHTYRMCGTKDTVIFTDRLMAMGFAFACRAGISFGKDDMVIPEAKRKLVDAAQEKVKEIEKQYTDGLITEGEKYNKVVDIWSHCTERVADEMMGTISTDTVLNKDGEMVEQPSFNSIFMMANSGARGSAAQMRQLAGMRGLMAKPSGEIMETPITANFREGLTVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDCIVREEDCGTSIGITVAALVEGNDVVETLGDRLLGRTPVSDIKDPITDELLVKAGTIMDEDIVEKIENSNVDSVLIRSPLTCETTRGVCVTCYGRDLARGTRVTVGEAVGVIAAQSIGEPGTQLTMRTFHIGGTASRQAEQSHQETTHGGVLKFHDLITVQDRAGRYVVLSRNSEVSLHEAVEHEGQVEAGRERERYRIPYGARISSAPGSVVEKGTTFAEWDPFAMPIITEVEGIVKFGDLVDGVSLRENMDDTTGLISKEVTEWKGQSSKKGDMRPRITLKDVNSNETLMMPNGSECRYYLPVGAVIVVNEGDHVHGGDIIAKVLRQSTKNRDITGGLPRVVELFEARKPKEHSFIAENEGMVTYGKDLKGKRRLVVTPDSGEPMEYLLPKGKQLAVNEGDWVRKGEPLMEGSPVPQDILKVLGLEELCRFMVNEIQEVYRLQGVRINDKHIEVIVRQMLQKVQITDPGDTMFVSGEQVEKDDYLLENVKTDKRGGRVATCTPLLLGITKASLSTPSFISAASFQETTRVLTEAAISGRVDTLNGLKENVIVGRLIPAGTGNILSQLKKMGSLTKGEKSTQGGEQHVAKVASSSEVTEG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RS30_MOUSE
Sequence: MQLFVRAQELHTLEVTGQETVAQIKDHVASLEGIAPEDQVVLLAGSPLEDEATLGQCGVEALTTLEVAGRMLGGKVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPNANS
What is the function of this protein?
Component of the 40S subunit of the ribosome (PubMed:36517592).  Contributes to the assembly and function of 40S ribosomal subunits (By similarity).
What are the official names of this protein?
FAU ubiquitin-like and ribosomal protein S30.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS30 family.
Protein: PANB_AFIC5
Sequence: MSIQNAARRKTAPEIFARKSGEPIVMLTSYHAHTAALVDKYCDIILVGDSLGNVMHGFETTVPVTLEMMILQGHAVMRGSKQALVVVDMPFGSYEASKEQAFHSAARVLKETGCGAIKVEGGQRMAETIAFLVNRGVPVMGHVGLTPQSINTLGSFRARGRDEADSAMILEDAKAVSEAGAFSIVVEAVAEPLGRKITEAVAAPTIGIGASVACDGQVLVLEDMLGLSPWAPKFVKRYGDLGPGIEKAIQDYADEVRSRAFPGPEHVYNLKPKAAK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_YERE8
Sequence: MSEKHPGPLVVTGKLSDGERMKSQSNFLRGTIAEDLNDGLTGGFNGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMMLRCRLPGGIITPQQWLGIDKFAADNTLYGSIRITNRQTFQFHGILKGNVKPAHQLLNQLGLDALATANDVNRNVLCTSNPVESVLHQEAYEWAKKISEHLLPRTRAYAEIWLDAEKVATTDEEPILGATYLPRKFKTTVVIPPQNDVDLHANDLNFVAVADKGKLVGFNVLVGGGLSIAHGDKNTYPRKASEFGYIPLQHTLAIAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVEVFKAEVEKRAGVSFGAIKPYQFTGRGDRIGWVKGIDKKWHLTLFIENGRLLDYPGRSLKTGVAEIAKIHQGDFRLTANQNLIVAGVPEKDKARIEALAREHGLMDDSVSPQRENSMACVSFPTCPLAMAEAERFLPEFVTRIEGILQQHGLPDEHIVMRVTGCPNGCGRALLAEMGLVGKAVGRYNLHLGGNREGTRIPRMYRENITEDEILAITDQLVGRWAKERHTDEGFGDFVIRVGVIAPVIDSARDFYDVQEAV
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: EIF3B_MOUSE
Sequence: MQDAENVAVPEAAEERAEPARQQPASESPPTDEAAGSGGSEVGQTEDAEEDAEAGPEPEVRAKPAAQSEEETATSPAASPTPQSAERSPSQEPSAPGKAEAVGEQARGHPSAGAEEEGGSDGSAAEAEPRALENGEADEPSFSDPEDFVDDVSEEELLGDVLKDRPQEADGIDSVIVVDNVPQVGPDRLEKLKNVIHKIFSKFGKIINDYYPEEDGKTKGYIFLEYASPAHAVDAVKNADGYKLDKQHTFRVNLFTDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDPVSIEERARWTETYVRWSPKGTYLATFHQRGIALWGGDKFKQIQRFSHQGVQLIDFSPCERYLVTFSPLMDTQDDPQAIIIWDILTGHKKRGFHCESSAHWPIFKWSHDGKFFARMTLDTLSIYETPSMGLLDKKSLKISGIKDFSWSPGGNIIAFWVPEDKDIPARVTLMQLPTRQEIRVRNLFNVVDCKLHWQKNGDYLCVKVDRTPKGTQGVVTNFEIFRMREKQVPVDVVEMKETIIAFAWEPNGSKFAVLHGEAPRISVSFYHVKSNGKIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAFVDTSDCTVMNIAEHYMASDVEWDPTGRYVVTSVSWWSHKVDNAYWLWTFQGRLLQKNNKDRFCQLLWRPRPPTLLSQDQIKQIKKDLKKYSKIFEQKDRLSQSKASKELVERRRTMMEDFRQYRKMAQELYMKQKNERLELRGGVDTDELDSNVDDWEEETIEFFVTEEVIPLGSQE
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit B, eIF3b, Eukaryotic translation initiation factor 3 subunit 9, eIF-3-eta, eIF3 p116.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVE2_BACSU
Sequence: MTKQTIRVELTSTKKPKPDPNQLSFGRVFTDHMFVMDYAADKGWYDPRIIPYQPLSMDPAAMVYHYGQTVFEGLKAYVSEDDHVLLFRPEKNMERLNQSNDRLCIPQIDEEQVLEGLKQLVAIDKDWIPNAEGTSLYIRPFIIATEPFLGVAASHTYKLLIILSPVGSYYKEGIKPVKIAVESEFVRAVKGGTGNAKTAGNYASSLKAQQVAEEKGFSQVLWLDGIEKKYIEEVGSMNIFFKINGEIVTPMLNGSILEGITRNSVIALLKHWGLQVSERKIAIDEVIQAHKDGILEEAFGTGTAAVISPVGELIWQDETLSINNGETGEIAKKLYDTITGIQKGAVADEFGWTTEVAALTESK
What is the function of this protein?
Transaminates branched-chain amino acids and ketoglutarate.
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase 2, BCAT 2, Vegetative protein 85, VEG85.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: CFT1_CANAL
Sequence: MDAYREFIDPSKVNNCVGCNFISSTKKNLIVGKGSLLQIFETIQLKQSTINKPQYRLKLIDQFKLQGTITDLKSIRTIENPNLDYLMVSTKYAKFSIIKWDHHLNTIATVSLHYYEHCIQNSTFEKLAVSELILEPTYNSVSCLRFKNLLCFLPFEVIEDDEDEEEEEEEDEEDEDEGEENIDDTKEKKDKKQSKTDTIEEDKNSTTTNQEPRLFYDSSFIIDATTLDSSIDTVVDMQFLHNYREPTIAVLSSKQEVWAGNLIKSKDNIQFQVLTLDLNLKSTISVFKIDNLPYEIDRIIPLPSPLNGTLLVGCNELIHVDNGGVLKRIAVNKFTRLITASFKSFQDQSDLNLKLENCSVVPIPDDHRVLLILQTGEFYFINFELDGKSIKRIHIDNVDKKTYDKIQLNHPGEVAILDKNMLFIANSNGNSPLIQVRYRDSSKTSDTKESKLNKIEEKEDNKDDDDNDDDDEDDLYKEEEEEETQKTISKSHIEFLYHDELINNGPSSTFTLGICSKEKFKCNLPNPNYNEVSILSNAGTDSQTKLNIITPTIQPSISSSLTFSQVNRMWNLNQKYLITSDDVNYKSEIFQIEKSYARMKSKHFINNELTINMHELNNGKFILQVTPKQIVLYDNKFKKRFTLNDEIKDDEILSSILRDEFLMIFLASGDVMIFVINTYNESYDKIEIPKLLDDTIITTGYITNSYLLSAVSKNVNLLLDNNTSSNKRKRKHSALSNSEGSKKNTGKSQPSTAAPPPPPKVNKVKTFVLVTGDNRIVAFNRFHGEKCYQLNHVDKFTENLSLGFFDPNQSTVDPFIKQIMLNELGDKFDTKDEYLTILTIGGEIYMYKLYFDGENYFFKKEKDLTITGAPDNAFPYGTSIERRLVYFPNLNGFTSIFVTGVIPYLILKTVHSIPRIFQFSKIAAMSISAFSDSKIKNGLIFLDNQQNARICELPLDFNYEFNLPMKHVDIGESIKSIAYHETSDTVVLSTFKQIPYDCLDEEGKPIAGIIKDIKDTPAMSFKGSIKLVSPYNWTVIETIELEDNEVGMTLKSMILDVGSESGSTLGSDPNSLIKKYNKKKREYIVIGIGKYRMEDLAANGIFKIYEIIDIIPEPGKPETNHKFKEIFKEETRGAITSICELSGRFLVSQGQKVIVRDLQDDGTVPVAFLDTPVYVSESKSFGNLLILGDPLKGCWLVGFDAEPFRMIMLGKDTQHISVECADFIINDDEIFVLVADNNNVLHLLNYDPDDPQSINGTKLLTKASFELNSTISCLRSLPLIDIEESVQTDALTNIAVPPPLPPNTTSNYFQVIGSTQDGSFFNVFPINEAAYRRMYILQQQLIDKEFHYCGLNPRLNRIGSIKLQNNETNTKPILDYDLIRRFTKLSDDRKRNLANKVSGKGIYQDIWKDIIRFEHTLNDL
What is the function of this protein?
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Involved in poly(A) site recognition.  May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
What are the official names of this protein?
Protein CFT1, Cleavage factor two protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SPDE3_HUMAN
Sequence: MTSHQPQPQEEQSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLAPGVDPSPPRRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLAPGVDPSPPRRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLAPGVDPSPPRRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLAPGVDPSPPRRSLGCKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQKIFYFLYGKTHSHIPLRPKHWFQLCRPMNPRARKNCSQIALFQKRRFQFFCSMRCRAWVSPEELEEIQAYDPEHWVWARDRAHLS
What are the official names of this protein?
Speedy protein E3.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: RUVA_THEAB
Sequence: MIHALNGKVESIENGKVYVNVNDLIYEIIVGDTGDFEEYINRNVKIYTKMVVNDDGISLYGFLEVIKLKLFEKLIGVNKLGPKSALKIISSNSVESVVSAIINEDVKALSSLPGIGPKTAERIVLELKDTIKELDVSINEKDRKVLEAIEALVTLGFNRNQAKKAVNKVAAKDDKLDDIIKKALRFLSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: UPP_DEIRA
Sequence: MCLMVTLVEHPLVQHKLSLMRDERTGVKEFRELAGELSLLLAYEAMRDLEVEPVRFATPIEEGDFPMLSGKKLALVAILRAGLVMTDAIVTLVPAAKVGHIGMYRDPQSLAPVAYYSKLPADIAERRVFLTDPMLATGGSANAAIQNLKDAGAQSIKLMTILAAPEGIHAVQQAHPDVDIVTASVDSRLNDHGYIVPGLGDAGDRIYGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RL18A_THEGJ
Sequence: MEVKVYRVKGIFQRGKLKQPFTKEYRALKPEHVEELVYSEIGSKHRVPRTKIWIESIEEIKPEEAENPVVRRLSLEL
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: SYL_ALKMQ
Sequence: MAIYDFGNIEKKWQERWQENKAFSIIERDRPKYYVLEMFPYPSGKIHMGHVRNYSIGDVVARFKRMKGYNVLHPMGWDSFGLPAENAAIKHGIHPDHWTKENVKEMKEQLDALGLSYDWDREVSTCTPEYYKWTQWLFLQFYHKGLAYKKESQVNWCPSCETVLANEQVVNGGCDRCDSSVGKKNLNQWYFKITDYAEALLEDIKLLDGWPEKVKTMQQNWIGKSHGAEIDFPIENTSKELKVFTTRPDTIYGATYMVLAPEHPYVMELVKETEYEEAVVAFRNKLQHMSDIERTSTEIEKEGIFIGKYCINPVSNEKIPIYIANYVLADYGTGAIMAVPAHDQRDLDFARKYDITVTPVIRPIDESDGFDIEKEAYTDSGIMINSEKFNGLDSEKAYEDIAKHIETLNAGKRTINYRLRDWLLSRQRYWGTPIPIIYCDDCGIVPVREEELPVKLPVDVTFSGKGSSPLETSEGFLNTNCPSCGKMAKRETDTMDTFVDSSWYFLRYTDANNEQLPFSKEAANYWVPVDQYIGGVEHAILHLLYSRFFTKVMKDLGLTDQPEPFKKLLTQGMVLKDGAKMSKSKGNVVSPEEIIQKYGADTARLFVLFAAPPERDLEWSDQGVEGSYRFLNRVWRLAEEFIDNNLFMSTSLGEALTKRDKDLKYTIHYTIKKVTSDVEDRFNFNTAISAVMELINELYKYKETDPSKLNGDLFREGIETSILLLAPFAPHFTEELWEKLGKAESVHMTNWPEYDHEAIIKDEVEIVMQVNGKVKDRMMVPTNVSKEELESLAMKNEKIIQIIEGKQIIKIIAVPKKLVNIVIK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LLDD_SHIBS
Sequence: MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADTHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAKGNAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YG06_SCHPO
Sequence: MIKDLENEIYKSRKNLNNILVLFDYIDLSNHSIDEVNDAAAALCRVYCYLSRNGLLKRPKEDDSSANAQVKNWVCDNYINYTEKLTEIFSMANVEALQVSFLTMTMRLCKAESQMDENGTFRNQFYIRFCLELLSSSQLSDICIKDFVTSYLVPYDDVRFFFYKNSKKVISSLIESSKTDDPMANLDIVAFNTIRILSAIPSPLPSSSTSSWADEPSPSSTETSSIKRAFQESWLSALSLPLSVNLYKQVLNVIHKRVIPFLQKPNLLMDFLTDAYNSHHAVSLLALNGLFTLMISHNLDYPLFYPKLYALLDRNLLYLKTRSRFFRLLDLFLSSTHLPATLIASFIKRLARLALTAPPGAIAIVIPFIYNCLQRHPTCMQMLHRSSAESGDSFDFDQPDPLLTGAIESSLWELSTLQNHYYSNIASLASIMSQKFTKPRYELEDFLDHGYATMCDAELRRPLKNEPPIEFEKRTLASGLEKSWI
What are the official names of this protein?
Uncharacterized protein C1604.06c.
What is the protein family that this protein belongs to?
Belongs to the CBF/MAK21 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: COA3_BOVIN
Sequence: MATPGPGDPVDAKSGKAPLAQRIDPTREKLTPAQLQFMRQAQLAQWQKTLPQRRTRNIVTGLGIGALVLAIYGYTFYSVSQERFLDELEDEAKAARARALERASGH
What is the function of this protein?
Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly.  MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion.  Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
What are the official names of this protein?
Cytochrome c oxidase assembly factor 3 homolog, mitochondrial, Coiled-coil domain-containing protein 56.
What is the protein family that this protein belongs to?
Belongs to the COA3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RSMG_RENSM
Sequence: MLEMTEAVASAAHSVFGDRLPLAQRYVEHLATSGIERGLIGPREVPRLWDRHVLNCAVVVELIEIDATVADVGSGAGLPGLCLALARPDLSITLIEPLERRVTWLSEVVADLGLSDQVTLFRMRAEQAVDEVNCSVVTARAVSALDKLAGLTIPLLHGNGQFLAVKGRSAAEEITKAAKAVRKLGGTRTDVLVAGSSVLEEPTTVVRILVGSAHR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANB_SALTY
Sequence: MKPTTISLLQKCKQEKKRFATITAYDYSFAKLFADEGINVMLVGDSLGMTIQGHDSTLPVTVEDIAYHTRAVRRGAPNCLLLSDLPFMAYATPEQACENAAIVMRAGANMVKIEGGAWLVDTVKMLTERAVPVCGHLGLTPQSVNIFGGYKIQGRGDAGQVLLDDALALEAAGAQLLVLECVPVELAKRVTEALSIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAEAGDMRAAVQQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4142_DICDI
Sequence: MMHALGDLFKPEEKEIKMDRDKCSGACVAIWTWKTIVRLICLIAGGVQVFMGGYIFYSISFTKDHSVQNYLSLSVVGFYACLTGLLILFAETRTRWTRRAVKVFVFLCNGLSRGIIYILIGAIDQSPIPFKFLNIITSMHIGLVCIAGGVVSIIEFLITYRRNRARLNQAIANHQQQAKGTELYDLFEREDFNNPEDAAAYDLEKGKDPNYIHQDLEMQPVQEA
What are the official names of this protein?
Uncharacterized transmembrane protein DDB_G0281339.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.