PharMolix/UniProtQA huggingface dataset:
Protein: NSP1_ROTPC
Sequence: MANSYREMLYWFGKTIDRNLPYVNTNGWRKQKGRKDGICLNCLDECKLYSCDHCGIKHKCGNCVLSECFLDVKNEFNKYRWLVFDEEPDQAVLLQHWIMYKDYFLQKFNYRLATQAKILNMNKNQKFQLNEGRKRALSVPITSQFLKFRLFGKIYIQFGTIMTNKIQPWLELSTLKIGYLQLLNVERCSELMATRGQFTTNVAKTACITEIKCRRPIYDNDCIIEAYLDKNDRGWKFAAILGRRKIPVTQKLAMEYFMKSLRAELFYYAHSRCHTLSNCPRWNEGLRLLNSSTLNIVFRRQFMNEIVEWFEIFSQYTGSHYEFITECVHDKSAITAFKQEIEDYIKEGKQITLKSVVPEEHAAYRHILRLRESLMLAIDAALSRIRSQSMGVL
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: HES3_MOUSE
Sequence: MEKKRRARINVSLEQLRSLLERHYSHQIRKRKLEKADILELSVKYMRSLQNSLQGLWPVPSGVDYPSGFQGGLRGVSQRLRPGEGDSGLRCPLLLQRREGSTTDSANPQATSVLNPCLPAIWAPSRAAGGSHSPQSPLPLPGGLLESSTDVVAPHPASNCQAESTRPGFRVWRPW
What is the function of this protein?
Transcriptional repressor of genes that require a bHLH protein for their transcription.
What are the official names of this protein?
Transcription factor HES-3, Hairy and enhancer of split 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYM_ALIFM
Sequence: MATDPRKILVTCALPYANGSIHLGHMLEHIQADIWVRYQRLRGNDVNFICADDAHGTPIMLKAQQMGISPEEMIAAVSEEHQKDFAGFDISFDNYHSTHSDENRELASHIYLELKKNGFITSRTISQLFDPEKEMFLPDRFVKGTCPKCKAEEQYGDNCDNCGETYSPTDLINPKSAVSGATPVMKDSEHFFFDLPQFESMLKEWTRSGSLQTETANKMQEWFESGLQQWDISRDAPYFGFEIPGETNKFFYVWLDAPIGYMGSFKNLCNKRDDLNFDEYWKKDSTTELYHFIGKDIVYFHSLFWPAMLDGAGFRKPNNVFVHGYVTVNGAKMSKSKGTFIKAGTYLNHLDPECLRYYYAAKLNSRIDDLDLNLEDFTQRVNSDVVNKIVNLASRNAGFITKRFDGKLADNFAEPELYNEFIAAADRIAELYETREFGRAIREITALADKANQYIDEKAPWVLAKEEGKEQELQEVSSVGINLFRVLMAYLKPVMPELAARTEAFLNETLTWEGVAQPLVAHEITKFKALFARIDPKKVEAMIEESKEDAAIEMAAKEKAEAEKEKASQTELDKDPIADEIEFDAFEAVDMRIARIISCEEVPKANKLLKFQLDIGGETRQVFSGIKSAYKPEELEGKLTVMVANLKPRKMKFGMSEGMILAAGPGGKDLWILEPHEGAQPGMRVM
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_PROM4
Sequence: MSLSNNNSNRVAIIGASGYGGLQLMRLLSDHPHFKVTFLGGNKTAGNKWHQIAPFIKSSEDLTVRKADPEDIAEHADFALLSLPNGLSSQLTPELIKRNIRIVDLSADYRYRSLYQWKQVYVKESTKYIRNDDSLCREATYGIPEWNEGDIRKSKLVACPGCFPTASLLPLMPFLKQGLVENEGLIIDAKSGTSGGGREPKEHLLLSECSESIAPYSVLGHRHTSEIEQQATLVSGTPIQLQFTPHLVPMVRGLLSTVYARLRDPGLTAEDCKTVLEAFYRSHSTVEILPVGIYPSTKWARYTNKALLSLQVDKRNGRLILVSVIDNLIKGQAGQAIQNLNIMAGFSHELGLPLTTFYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_CLOAB
Sequence: MRINILSEDTSNKIAAGEVVERPFSVVKELVENSIDAGAKTINIEIENGGRTLIKVLDDGYGIDKDDIEKAFMPHATSKISKLQDIYSINTLGFRGEALPSIASVSKTTLKSRTKENEFGREISISGGSVDYIKDCGTNIGTHIEVRDLFYNVPAREKFLKSTAKEASSISDIVNRLALAHSEISFRLINNGKRVITTYATDNLIDTIRAIYGKKICDNVISFERHTDLVSVHGYVGNAEISRGSRNNQSIFINKRYIKNKLITAAVENAVKSFMMINKFPFFIIFLDIFPEFVDVNVHPTKSEVKFQNERDIFKIIFDTVHEGIRNSLKESFKVEALKEEEDKLFDIKEDVITKNEIKHDDKIDGYIKKDSFPVPVQIPIDLKRPIENYDNSTKENKDRSFDDFREKDIIKETSQEKETYDIITNKKAKFPELRVIGQFNNTYILAESFEELYIIDQHAAHEKILFEKYREDIKNKGVSSQILITPSVVELLPEDFIYYDENKEVFKNAGFVIEYFGDNTVAIKEVPLFLGKPLVKDLFLEIIDNLKNMGSGETSEVKYRSIATAACKSAVKAYHELTHDEMKTLIQDLRFAEDPFNCPHGRPTIVRLTVTDFEKKFKRIQ
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: RK2_ACOAM
Sequence: MAIHLYKTSTSSTRNGAVDSQVKSNPRNNLIYGQHHCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNKKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPISMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLISKNCSATVGQVGNVGANQQSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDRFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KATG_PSEPW
Sequence: MSNESKCPFHQTAGGGTTNRDWWPDQLNLRILHQHGTKSDPMDPDFDYAKAFKSLDFQALKQDLTALMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRIGDGRGGAGSGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGNKISWADLIVLTGNVALESMGFKTFGFSGGRADVWEPDEDVYWGSEKVWLGGDTRYGKDQVKAQAPGQGDLVAEPAKHGEEQNRDLSAERNLENPLAAVQMGLIYVNPEGPEGNPDPVASGKDIRETFGRMAMNDEETVALIAGGHAFGKTHGAGPADNVGAEPEAAGLELQGLGWANKFGTGKGGDTITSGLEVTWTSTPTQWSNEYLNNLFNFEWELTKSPAGAHQWQPKEGKGAGTVPDAHDPSKRHAPSMLTSDLALRFDPIYEPIARRFKDNPDQLADAFARAWYKLIHRDMGPLARYLGPEMPNEELLWQDPLPKADQPLPSEQDIAALKTKVLASGLSVGELVSTAWAAASTFRGSDKRGGANGARLRLAPQKDWPANQGTGKVLAALEQIQGEFNNGGKHISLADLIVLAGTAAVEKAAKDAGYAGNVQFRPGRVDASQEQTDVESFAVLEPLADGFRNFTKARYSVKAEKLLLDKAQLLTLTAPELTVLIGGLRVLGANHGGSKHGVFTDQPGTLSNDFFRNLLDMGVEWKATSGDNESFEGRDRKTGQVKWTGTRVDLVFGSHAQLRALSEVYGSSDGKDKFVKDFVAAWVKVMELDRFDLK
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: ZDBF2_MOUSE
Sequence: MEAQSYQEVMKNNGQHLFSSQHRSLTRQSRRRTATNNTLMERFLQDVLRHHPYNYQDNRSAPNEPEAAAAAAAAADPGSPEVVVVLDDSDEKEDDTADSGAERNSEDSGSVEEIDYRPGTSQEHAEVAVRPSVIQKLERGQQQSLELAHKVESGVKKVNSVGVVQATTSGKKLVRPPVICNAPASSLPSGSFERPVAANSVPRLVLAVASDSFPACDTENLETYFDSPDQGPSNPSSQPKTKDPKKKLSINLDKLLAQRNLRAKGASFSPVVRVRELTGSELCSVRAESSELEAGTAGNPRETDTLPEQAREGAIPKRREASRSNTVRPQEETRLVLNKPTLLKQKRSVSSEERFSCGSRQAVPGPSQAAVRDLSLLEEEVEEEKQEEEEEEEQEEEEEHEEEEEGVDQEDASYESRGSDMSFDCGSSCQSLSALSELTAREINVSEETHAYSQPRNETPTVSGATSDNGSSSRQVITQNIQLISLVDESYESSGSEVNFDGDDSLPSTSHRPPQPVEVVVPLRLVDKSYGSGSSEPCEDSGSSADETPAASRQQNPVRNTHANLVDENYGSSSFSSDSDAALDHPQVPVQEGSPRGRAVGQGNEEQPSSAEAHPERDGSLETVAHELQRESQEINLPNQKNTSLGDMNCESHGPEVGFHADAQLEADQSPVNPEEVDLDLENQSVHSGISNLSFDSNASYQSANDQPQGAWGEVNLDELNVDMEVKSNGCSSSELTFDSDSPLLSVTERSLLDFEGLNEDDFNLEDENCVSSSSDITFDSDIPDDSVADQPQVAVYEEEPVGLENKSNESCVSGITFDSDIPLHSGNDHPEVAVKEVIIKEDENVHLEGKNDNPSGSEICLDSNVPLHSVTNSDVAVKKINPPKEDQVQIEQIEQKENEPTDSELNLDCNSVNSKPGCSEDPIILRVSETRLDSHVPFQSVIRKCEVVVKNVCLQKEKHAELTSKSTESHSEVSSASTASHPVTEPYVGKKAKRKTKHLEEVNSDDEYGGSQPTFKFDVFPRTMTEKPQPAALKEGHADPKDKITELRGMAVNVNTADCLDSVLSQPQLASNENCVELKDTDGKPSDSKASADSTGHFHSLPKQEFDVVSKMNEWKKEAKVLEQKISDLIYSKIIHDSNVSFRSAMDQLELALKQISLGNNDQVSLEDNSQDTCSETNLDSGFSVQAVVEPPEPEVTVLEPEHVEQEGRNNVPCDSEVSVDANGSVQLEAGQHSESGENRSQKDTDDTEGKRDDAQGFGITCDSNVPQPLAGHIEVVQDIDHWKDHVDLEDKLGESKNSKVNFHSDEPLQAVTNATQEPVEEINLPRGRASPNGNGCEPYGSTIVPVTNVIFCSVIQKPQRLQKKCTSLKENSSNPCPEVNVDSCDGPEVSVDSNDPCQSVAGHLQKPDKEMNLKEDHIYLEDKSYKLVDFEPTYDSDDPVQFVTVPSVEAVSIKEVNLQKENPDDLENENFQPCCSEVACNSAVHLQSEADPPQVACKEADLDKKALDIEDKGSVTCVPEVVYDSDVSFQIVVNQVQTSDGETDSPQVVFVDVVSSDSDCDREVISDSNIPLQLEPPQMTVKETSDINTDSLGSAANEKYYCKFCGCDYEASQSVTNQSKESFKIINRKNDYIILGDSTCPSCGHELNFNVDPSDQPTTCQLQQPDRNFIDPEDKNFGSKCPKRKLNWEDTAHPVTHQLQKTGEATSLRKDQKNRFKRDRGWESSSFAGDHAAYAVSVIRQTALNSCGSELNFQDDTFYHSDIDPPQPKKKGQGKKVTFDLRVTKYEYPPNPMYGEGEEVAEDDLKEVVVHEASPQGQAPPSIVGKTCPQGREDDVKTNTQACQGYFYSYYDGGSETKKILLGEEEKTIRSDLNQNTTSIQHVKGKVGDTGDFSVDLGKQSCSLAEGLHQQHGQVTSQNQVEVRCGIQASSGKKRKITEQEEDSPKRKCFHHDSQKKKKAQAGITELPEPQTKVLEPVQPDSLVYIFSSLSMKEDQSLNPPKTKPGSDSDLPHIYSCREHTSSGPRRKRTVINPPQNLMVPEVGIDLNRHDPKPNAGDDSAKRQNLVSTSFMAMPKKSVLKFQRTNQSSFLKKSEDVGATQVPKDNFQQTLVNRDGAKKFPKSVKKEDLESQNQRKFWKKKMVAANKLCLIKNAYKTMVLRKKSKLASEKLAIWIQLKATDIIRKYVSRCHGLMPRRHLSKTVLIRMQLRKKKIVARKIKEAKRAAEALALKLSRPSCPPRAPCPPRALCPPRAPCPPRALCPPRAPCPPRALCTPRAPCPPRALCTPRAPCPPRALCTPRAPCPPRALRAPCPPRALCSPRAPCPPRALCPPRAPCPPRAPRAPCPPRAPCPPRAPCLPRAPCPPRAPCPPRAPCLPRAPCLPQAPCPPRALCLPRVSCPPLPLCAPCPPCAPVLPAGAEEQLSTTAGPAELPAHLSNAGGIKRYRKTYFRRRKRLLPVREYDLRSLSSTTNTDRMVTRLASKSKSNEAK
What are the official names of this protein?
DBF4-type zinc finger-containing protein 2 homolog.
Protein: S17A9_MOUSE
Sequence: MPSQRSSLMQPIPEETRKTPSAAAEDTRWSRPECQAWTGILLLGTCLLYCARVTMPVCTVAMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGFITVTTPLLAHLGSGHLAFLTFSRILTGLLQGVYFPALTSLLSQKVQESERAFTYSTVGAGSQVGTLVTGGVGSVLLDQCGWQSVFYFSGGLTLLWAYYVYRYLLNEKDLVLALGFLAQGLPVTKPSKVPWRQLFRKASVWAAICSQLCSACSFFILLSWLPTFFKETFPNSKGWVFNVVPWMLAIPASLFSGFISDRLISQGYRVITVRKFMQVMGLGLSSIFALCLGHTTSFLKAMIFASASIGFQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLSGYLIETTGSWTCVFHLVAIISNLGLGTFLVFGKAQRVDLVPTHEDL
What is the function of this protein?
Involved in vesicular storage and exocytosis of ATP.  May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles (By similarity).
What are the official names of this protein?
Solute carrier family 17 member 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PFKA_STRPQ
Sequence: MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGQIIVNNPHKARLDFAALNRSLSQ
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPA_DROME
Sequence: MMMNAFIEPAQHHLASYGLRMSPNTTASNSNAQQQQQQQLEMTQQQQQQQQQQQQQQQQDQESAAATAAAYQNSGYGHFNSYASRDFLLGRREAEYGVAGSAGQASAAADSMLFSGFPAQAAELGSGFGQHPFHSHHHHHQMRMGMADAYAAGHPYNHHGNFPTAAVHHPVVHHPSHHAMSAMHPAGAGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPGLVPPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAGSSSGVSSLSGGSGIKSSPHSIKSEPNPMHSVHLGASSSGSSSTASSSASHLLQHQQHQHQQQQQQQQHQQQAQQQQQLTAHPSDPKSSPALQLMAASASAYLPPPLGPPPSHHHHPHHHQAAPSPGAAAASASMLHHNHHLLYHPAAQHHPPSDWYHTTAPSGSAEAMNPLNHFGHHHHHHHLMHPGAATAY
What is the function of this protein?
Transcription factor essential for parasegmental subdivision of the embryo.  It is involved in the activation of wingless (wg) in odd parasegments.  It is also required for the timely activation of wg in the remaining parasegments and for the timely activation of engrailed (en) in all parasegments.
What are the official names of this protein?
Pair-rule protein odd-paired.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EMC8_BOVIN
Sequence: MPGVKLTTQAYCKMVLHGAKYPHCAVDGLLVAEKQKPRKEHLPLGGPGAHHTLFVDCIPLFHGTLALAPMLEVALTLIDSWCKDNSYVIAGYYQANERVKDASPNQVAEKVASRIAEGFSDTALIMVDNTKFTMDCVVPTIHVYEHHENKWRCRDPHYDYCEDWPEAQRISASLLDSRSYETLVDFDNHLDDIRNDWTNPEINKAVLHLC
What is the function of this protein?
Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.  Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues.  Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices.  It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes.  By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors.  By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes.
What are the official names of this protein?
ER membrane protein complex subunit 8, Neighbor of COX4.
What is the protein family that this protein belongs to?
Belongs to the EMC8/EMC9 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TR123_RAT
Sequence: MFSQKTNYSHLFTFSIIFYVEIVTGILGNGFIALVNIMDWLKRRRISTADQILTALALTRLIYVWSVLICILLLFLCPHLSMRPEMFTAIGVIWVVDNHFSIWLATCLGVFYFLKIASFSNSLFLYLKWRVKKVVLMIILISLIFLMLNISSLGMYDHFSIDVYEGNMSYNLVDSTHFPRIFLFTNSSKVFLIANSSHVFLPINSLFMLIPFTVSLVAFFVLFLSLWKHHKKMQVNAKGPRDASTMAHTKALQIGFSFLLLYAIYLLFIITGILNLDLMRCIVILLFDHISGAVFSISHSFVLILGNSKLRQATLSVLPCLRCRSKDMDTVVF
What is the function of this protein?
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.  Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
What are the official names of this protein?
Taste receptor type 2 member 123, T2R123, Taste receptor type 2 member 2, T2R2, Taste receptor type 2 member 23, T2R23.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SUCB_ARATH
Sequence: MRGLVNKLVSRSLSISGKWQNQQLRRLNIHEYQGAELMGKYGVNVPKGVAASSLEEVKKAIQDVFPNESELVVKSQILAGGRGLGTFKSGLKGGVHIVKRDEAEEIAGKMLGQVLVTKQTGPQGKVVSKVYLCEKLSLVNEMYFSIILDRKSAGPLIIACKKGGTSIEDLAEKFPDMIIKVPIDVFAGITDEDAAKVVDGLAPKAADRKDSIEQVKKLYELFRKTDCTMLEINPLAETSTNQLVAADAKLNFDDNAAFRQKEVFAMRDPTQEDPREVAAAKVDLNYIGLDGEIGCMVNGAGLAMATMDIIKLHGGTPANFLDVGGNASEHQVVEAFKILTSDDKVKAILVNIFGGIMKCDVIASGIVNAAKEVALKVPVVVRLEGTNVEQGKRILKESGMKLITADDLDDAAEKAVKALAH
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, Succinyl-CoA synthetase beta chain, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RBL_THEKO
Sequence: MVEKFDTIYDYYVDKGYEPSKKRDIIAVFRVTPAEGYTIEQAAGAVAAESSTGTWTTLYPWYEQERWADLSAKAYDFHDMGDGSWIVRIAYPFHAFEEANLPGLLASIAGNIFGMKRVKGLRLEDLYFPEKLIREFDGPAFGIEGVRKMLEIKDRPIYGVVPKPKVGYSPEEFEKLAYDLLSNGADYMKDDENLTSPWYNRFEERAEIMAKIIDKVENETGEKKTWFANITADLLEMEQRLEVLADLGLKHAMVDVVITGWGALRYIRDLAADYGLAIHGHRAMHAAFTRNPYHGISMFVLAKLYRLIGIDQLHVGTAGAGKLEGGKWDVIQNARILRESHYKPDENDVFHLEQKFYSIKAAFPTSSGGLHPGNIQPVIEALGTDIVLQLGGGTLGHPDGPAAGARAVRQAIDAIMQGIPLDEYAKTHKELARALEKWGHVTPV
What is the function of this protein?
Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3-phosphoglycerate (3-PGA) (PubMed:9988755, PubMed:10512715).  Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase (PubMed:17303759).
What are the official names of this protein?
Ribulose bisphosphate carboxylase, RuBisCO.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type III subfamily.
Protein: RL18E_NANEQ
Sequence: MVKPTGPTDVNVRKLIRQLEKTKRPIFKYIAELLSKPKRRKKHFVVNLWKIEKHSNDGDTIIVPGKVLGSGELTKDVKVVALSFSQTALEKLKDKAIYLENFVEQAKDKKLPNTKILI
What are the official names of this protein?
50S ribosomal protein L18e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
Protein: YN23_CAEEL
Sequence: MVAEVILPGRPTTLKADIREKIANFYNINPDTMAKNTPLSQDDKVAKTVEQRRKDAAAHKEAYNAMPEAERRHLNSEKYANRKAEVSYKHR
What are the official names of this protein?
Uncharacterized protein T26G10.3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: COAA_COXB1
Sequence: MTVKPELNEITPYLQFNRQEWGNFRKDTPLTLTESDLDKLQGQIEIVSLKEVTEIYLPLSRLLSFYVTARQTLQQATYQFLGKPEPKVPYIIGIAGSVAVGKSTTSRVLKALLSRWPDHPNVEVITTDGFLYSNAKLEKQGLMKRKGFPESYDMPSLLRVLNAIKSGQRNVRIPVYSHHYYDIVRGQYEIVDQPDIVILEGLNILQTGVRKTLQQLQVFVSDFFDFSLFVDAQAQVIQKWYIDRVLSFWRTTFKDPHSYFHYLTQMSETEVAAFAKHVWNEINKVNLMENILPYKNRAQLILEKAADHSIQKVYLRKI
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_SULIK
Sequence: MSSEKEYVEMLDRLYSKLPEKGRKEGTQALPNLIIFNIGNTTMIRNFAEYCDRIRREDKICMKYLLKELAAPGNVDDKGELIIQGKFSSQVINTLMERFLKAYVECSTCKSLDTVLKKEKKSWYIVCLACGAQTPVKPL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: SECA_THEP1
Sequence: MILFDKNKRILKKYAKMVSKINQIESDLRSKKNSELIRLSMVLKEKVNSFEDADEHLFEAFALVREAARRTLGMRPFDVQVMGGIALHEGKVAEMKTGEGKTLAATMPIYLNALIGKGVHLVTVNDYLARRDALWMGPVYLFLGLRVGVINSLGKSYEVVWKNPDLARKAIEENWSVWPDGFNGEVLKEESMNKEAVEAFQVELKEITRKEAYLCDVTYGTNNEFGFDYLRDNLVLDYNDKVQRGHFYAIVDEADSVLIDEARTPLIISGPSKESPSVYRRFAQIAKKFVKDKDFTVDEKARTIILTEEGVAKAEKIIGVENLYDPGNVSLLYHLINALKALHLFKKDVDYVVMNGEVIIVDEFTGRLLPGRRYSGGLHQAIEAKEGVPIKEESITYATITFQNYFRMYEKLAGMTGTAKTEESEFVQVYGMEVVVIPTHKPMIRKDHDDLVFRTQKEKYEKIVEEIEKRYKKGQPVLVGTTSIEKSELLSSMLKKKGIPHQVLNAKYHEKEAEIVAKAGQKGMVTIATNMAGRGTDIKLGPGVAELGGLCIIGTERHESRRIDNQLRGRAGRQGDPGESIFFLSLEDDLLRIFGSEQIGKVMNILKIEEGQPIQHPMLSKLIENIQKKVEGINFSIRKTLMEMDDVLDKQRRAVYSLRDQILLEKDYDEYLKDIFEDVVSTRVEEFCSGKNWDIESLKNSLSFFPAGLFDLDEKQFSSSEELHDYLFNRLWEEYQRKKQEIGEDYRKVIRFLMLRIIDDHWRRYLEEVEHVKEAVQLRSYGQKDPIVEFKKETYYMFDEMMRRINDTIANYVLRVVKVSEKDEKEAKEELGKIRLVHEEFNLVNRAMRRATEKKKKKDGLHSFGRIRVKR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: 72A61_PARPY
Sequence: MDSRVLGALAALLAAAAAWVMRAAAEWLWWRPRRLERSLRSQGVDGNLYRFLNGDLKETVRLTKEARAQPISPPSHRFLHRINPLLLRAISHHGKFALTWIGPTPRVSIMDPELVREVLSNKFGHFAKPKAAPIVKLLATGLANYEGEKWVRHRRIINPAFHLEKLKRMLPAFFSCCSELIGRWESLVGCDESREVDVWPELQNLTGDVISRTAFGSSYAEGRRIFQLQSEQAELLIQAVQTVYIPGYRFLPTPKNIRRTKIDKEVRALLRSIIEKRENAMKMGDVHDDLLGLLMEYNLKESEHFNSKNIGMTTEDVIEECKLFYFAGQETTSVLLTWTMILLGMHPSWQDRAREEVSQVFGKNKPDFDGLSRLKTVTMILYEVLRLYPPIIFLTRRTYKPMMLGGITFPPEVQLALPIIFIHHDPEFWGEDAEEFNPDRFADGVSKASKNQMAFFPFGWGPRICIGQGFAMLEAKMGLSMILQRFSFELSPNYSHAPHTKITLQPQHGAQMVLHRL
What is the function of this protein?
Involved in the biosynthesis of spiroketal steroid and saponin natural products from cholesterol such as diosgenin and analogs (e. g.  furostanol and spirostanol), plant defense compounds used as main precursors for the industrial production of steroid hormones (PubMed:31324795).  During the 5,6-spiroketalization of cholesterol, may catalyze the 27-monohydroxylation of furostanol-type steroid to an intermediate product that undergoes a stereospecific formation of the terminal heterocycle to yield diosgenin (PubMed:31324795).
What are the official names of this protein?
Cytochrome P450 CYP72A616, PpCYP72A616.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RSAD2_PONAB
Sequence: MWVLTPAAFAEKLLSVFRQPLSSLWRSLVPLFCWLRATFWLLATKRTKQQLVLREPDETKEEEEDPPLPATPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKINFSGGEPFLQDRGEYLGKLVKFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISCDSFDEEVNVLIGRGQGKKNHVENLQKLRTWCRDYRVAFKINSVINRFNVEEDMTEQIKALNPIRWKVFQCLLIEGENCGEDALREAERFVIDDEEFERSLERHKEVSCLVPESNQKMKDSYLILDEYMRFLNCRKGRKEPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLDW
What is the function of this protein?
Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon.  Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhCTP) via a SAM-dependent radical mechanism.  In turn, ddhCTP acts as a chain terminator for the RNA-dependent RNA polymerases from multiple viruses and directly inhibits viral replication.  Therefore, inhibits a wide range of DNA and RNA viruses.  Promotes also TLR7 and TLR9-dependent production of IFN-beta production in plasmacytoid dendritic cells (pDCs) by facilitating 'Lys-63'-linked ubiquitination of IRAK1 by TRAF6.  Plays a role in CD4+ T-cells activation and differentiation.  Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities.  Can inhibit secretion of soluble proteins.
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase RSAD2, SAND, Radical S-adenosyl methionine domain-containing protein 2, Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible, Viperin.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RSAD2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus. Endoplasmic reticulum. Lipid droplet. Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane.