PharMolix/UniProtQA huggingface dataset:
Protein: EST1_YEAST
Sequence: MDNEEVNEECMRLFFKNARAHLDKHLTSRLTCDENAYITFRCFLDGIHRKSTRFLEELLLKQENMYHNNNYERINDSVIPLVLKLLWLQIHEPTLQWFEHWFHDIMRLSNRRKFRVFRIFQKKMIQFFKITHRYYYDIIEHLCAKYDMNSVISNALFAKLNLMQYTDGLSTHEKIILNTSNPLTFSIVISLQRCVINLGSTHFYKTLLNKPSNKPKSVEGFEKSIRYLNIASLYLPAVGDTYFQRAKIYLITGKFSLYFFELVRGALVRIPSKCALNNLKDFILTPDFPERRRLMKKLAILVSKDLKGEKSFFEGQIVLQFLSIVEHTLVPQSWNASRASNCWLLKEHLQMAALKYHSGNINVILENLAATMGSFDLMFTTRKSKEQKNKLKYADLSERQVFFLDLSFDFIANIIDVVIKPSWQKNMEDFRYLAIIRLLMCWIKSYRSILQYTHRHRKFCTSFALLLNDLINSPLNCSGNIYSHRPKRSYLFREDIIFREFSCINFALTDFNDDYVYDSPDMINNIIGCPTLTKVLSPKEECVLRIRSIIFSGMKFLEKNDTGVIWNASKYKFDLISPNIKIKRQIALSEISSKINVKTQQERVVSSRKVEAKRDEQQRKRAGKIAVTELEKQFANVRRTKKLSPLPEKDGVSSELVKHAASRGRKTITGPLSSDFLSYPDEAIDADEDITVQVPDTPT
What is the function of this protein?
Directly involved in telomere replication.  Associates with telomerase and during its interaction with CDC13, telomerase activity is promoted.
What are the official names of this protein?
Telomere elongation protein EST1, Ever shorter telomeres protein 1.
What is the protein family that this protein belongs to?
Belongs to the EST1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: RS13_DICT6
Sequence: MARIAGVDLPSNKKIEIALTYIYGIGRTTSKKILQATGVDPNKRVKDLTEEEISKLREEIENNYKVEGDLRQEVAANIRRLIEIGCYRGIRHKRGLPVRGQRTRCNARTRKGPRKTVGAKRKEK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: YQGF_CORGL
Sequence: MKVSADTPGHDDPGPGRRLGLDVGTVRIGVAASDRDAKLAMPVETVPRETGFKGPDLADIDRLVAIVEEYNAVEVIVGLPTDLQGNGSASVKHAKEIAFRVRRRLTNAGKNIPVRLGDERLTTVVATQALRASGVSEKAGRKVIDQAAAVEILQTWLDARTRALEPQSTDTQDFDEKGNFPG
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_CAUVC
Sequence: MNAHVTPDSVTADSDETWTVAGRTFRSRLIVGTGKYKDYATNAAAARAAGAEIVTVAVRRVNLTDPSQPLLVDYVKPTEFTYLPNTAGCFTGEDAVRTLRLAREAGGWDLVKLEVLSDPKTLFPDMEETLRSLKLLVADGFQVMVYCSDDPVYARKLEEAGAVAIMPLGAPIGSGLGIQNRVNLRIIIENAKVPVLVDAGVGTASDAAIGMELGCDAILMNTAIAEAKDPIRMAKAMKHAVIAGREAYLAGRMQKRLYADPSSPLAGLI
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGBA_HELPJ
Sequence: MLRLLIGLLLMSFISLQSASWQEPLRVSIEFVDLPKKIIRFPAHDLKVGEFGFVVTKLSDYEIVNSEVVIIAVENGVATAKFKAFESMKQSHLPTPRMVAKKGDLVYFRQFNNQAFLIAPNDELYEQIRATNTDINFISSDLLVTFLNGFDPKIANLRKACNVYSVGVIYIVTTNTLNILSCESFEILEKRELDTSGVTKTSTPFFSRVEGIDAGTLGKLFSGSQSKNYFAYYDALVKKEKRKEVRIEKKEERIDARENKREIKQEAIKEPKKANQGTENAPTLEEKNYQKAERKFDAKEERRRSRDERKKTKATKKAMEFEEREKEHDERDEKETEERRKALEMDKGNEKVNAKENEREINQESANEPSSENNATLKDTENTSVLKESAAKKEAPKPSSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALEMNKK
What is the function of this protein?
Binds plasminogen, specifically, and in a concentration and lysine-dependent manner.  Plasminogen is the precursor of plasmin, a serine protease that cleaves fibrin, fibronectin, laminin and vitronectin.  Acquisition of plasminogen/plasmin could enable H. pylori to degrade host components (By similarity).
What are the official names of this protein?
Plasminogen-binding protein PgbA.
What are the subcellular locations of this protein?
Cell surface. Note=The plasminogen- binding region is localized on the surface the bacterium.
Protein: NUOI_ORITB
Sequence: MKITNFTKSFLLYEIIVGMFLTLKYFFKSKVTIRYPNEVSKLSPRFKGEHALRRYPDGEERCIACKLCEAICPAQAITIEAKEQPNGSRRTTKYDIDMTKCIYCGLCQEACPVDAIVEGPNLEFATETHQELLYNKEKLLRNGDMWEHVIAKNLKVDSIYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TX1A_MYRBA
Sequence: MKLSCLLLTLAIIVVLTIVHAPNVEAKALADPESDAVGFADAVGEADPNAIIGLVSKGTCVLVKTVCKKVLKQG
What is the function of this protein?
Shows moderate activity against E. coli and S. aureus (MIC<25 uM), slight activity against B. subtilis (MIC<50 uM), and no activity against L. garvieae, P. aeruginosa, C. albicans, and S. cerevisiae.  Has no hemolytic nor cytolytic activity.  Causes an IgE-independent histamine release.
What are the official names of this protein?
M-myrmeciitoxin-Mb1a, M-MIITX-Mb1a, Pilosulin-3.
What is the protein family that this protein belongs to?
Belongs to the formicidae venom precursor-01 superfamily. Ant pilosulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEC14_SCHPO
Sequence: MSETISDPYPLTNPNAPLGHPGHLNSTQQATLDSMRLELQKLGYTERLDDATLLRFLRARKFNLQQSLEMFIKCEKWRKEFGVDDLIKNFHYDEKEAVSKYYPQFYHKTDIDGRPVYVEQLGNIDLKKLYQITTPERMMQNLVYEYEMLALKRFPACSRKAGGLIETSCTIMDLKGVGITSIHSVYSYIRQASSISQDYYPERMGKFYVINAPWGFSSAFNLIKGFLDEATVKKIHILGSNYKSALLEQIPADNLPAKLGGNCQCPGGCELSDAGPWHEEQWMNKN
What is the function of this protein?
Has a direct role in controlling cell septation and in forespore membrane formation.
What are the official names of this protein?
Sec14 cytosolic factor, Phosphatidylinositol/phosphatidyl-choline transfer protein, PI/PC TP, Sporulation-specific protein 20.
What are the subcellular locations of this protein?
Nucleus. Prospore membrane. Note=Nuclear, during meiosis. Associated with the forespore membrane during sporulation. During interphase found at the cell poles and during M-phase is located at both the cell poles and the medial region.
Protein: THIC_MYXXD
Sequence: MSGASRSLKVDGKVLEGISRGPLPASRKVYVPGVLHPDLRVPLREISQTPTRLGHGPDAKETANPPVHVYDSSGPYTDPAAELDLRQGLPALRESWILGRNDTEALSGVSSEYGRAREADPRLAGLRFAHRRSPRVAKSGANVTQLHYARKGIITPEMEYVALRENLQVEASLAAQHPGQSWGAAIPRVITPEFVRDEIARGRAIIPANINHPELEPMIIGRNFLVKINANIGNSAVTSSIEEEVEKMVWSIRWGADTVMDLSTGRNIHETREWILRNAPVPIGTVPIYQALEKVGGKAEDLTWELYRDTLIEQCEQGVDYFTIHAGVLLRYVPWTAKRLTGIVSRGGSIMAKWCLAHHRENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSIADANDAAQFGELETLGELTQIAWKHDVQVMIEGPGHVPMHLIQENMTKQLAVCGEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGTAMLCYVTPKEHLGLPDRDDVKEGVITYKIAAHAADLAKGHPGAQARDNALSKARFEFRWEDQFNLSLDPERARAFHDETLPAEGAKVAHFCSMCGPQFCSMKITQEVRDFAAKQGVSDDTALQSALDEKSAEFKKAGSQLYR
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DBP5_PHANO
Sequence: MSATEPTKEPAKEEVAEQSTVAQAQVDGSGEPANGSPLTETEYKVEVKLADMQADPNNPLYSAQSFEELQLSEELLKGVRNMNFRKPSKIQEKALPLLLMNPPTNMIAQSQSGTGKTAAFSLNILSRIDLSRNEPQAIALAPSRELARQILGVITHMGQFMEGLKTMAAIPDPTKRNQRLDAHVLVGTPGTVQEQLKRRLIKSDSIKILVLDEADNMLDQQGMGDQCTRVKSLLPKNIQTVLFSATFPPAVINYANKFAPNSNVLTLAHEELTIEGIKQLYIDIDKDQDKYSTLLKFYGLMTQASSIIFVRTRRTAEELERRMVAEGHKVAQLSGALEGQDRDRVIDQFRSGEAKVLITTNVLARGIDVESVTMVINYDVPTMADGREADPETYLHRIGRTGRFGRVGVALTFVHDKASWQQLHDIASYFKTDLHPIDTSDWDNVEEMIQKIIKSSRAGKSTKEMTEMITS
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: FRDB_SHIFL
Sequence: MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACPQFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIATLKPR
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth.
What are the official names of this protein?
Fumarate reductase iron-sulfur subunit, Quinol-fumarate reductase iron-sulfur subunit, QFR iron-sulfur subunit.
What is the protein family that this protein belongs to?
Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLYA_SHIB3
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERIKGKVLDICARYPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP46_EMENI
Sequence: MDVIPSTTPGEAVRISAKRTAELFGPEYLMVTPSASNGSIGVSYRRKTEYEHVKELPPALAAKQAQAAAARSKRPKISSRSEGSGSGDKSGASTALVRRGGRASGAAGDDKPTSLIQRPSATRQQPPEWHAPWKLMRVISGHLGWVRSLAVEPNNEWFASGAGDRTIKIWNLATGALRLTLTGHISTVRGLAVSPRHPYLFSCGEDKMVKCWDLETNKVIRHYHGHLSGVYTLALHPRLDLLVTGGRDGVARVWDMRTRSNIHVLSGHTGTVADVQCQEADPQVITGSLDATVRLWDLAAGKTMGVLTHHKKGIRSLATHPREFTFASASTGSIKQWKCPGGEFMQNFEGHNAIINTLSVNEDNVLFSGGDNGSMSFWDWKTGYRYQTIDTTAQPGSLEAEAGIMTSTFDRTGLRLITGEADKTIKVWKQDDQATPETHPVTWAPTLGRQRY
What is the function of this protein?
Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
What are the official names of this protein?
Pre-mRNA-splicing factor prp46, Pre-mRNA-processing protein 46.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRL1/PRL2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL34_LACDB
Sequence: MSTKRTYQPKKRHRSRVHGFMKRMATSNGRKVLARRRAKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: HCHA_ECO55
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGTLIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRB_CELJU
Sequence: MSDNEKFNDALWREKLTPEQYRICREKGTERPFTGEYWQEFRPGRYHCRCCGELLFDADTKFDAGCGWPSFYTPATKTAVREQLDTSHGMYRTEVLCRRCDCHLGHVFTDGPEPTGLRYCINSASIVLDSEQVSFTPSTL
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: MTC6_YEAS2
Sequence: MWILIYLFIIWSSLRTWVTAVDSTTTVGDDLNETVSASVWPTMSPQMTVAFRSQRDVMGNLTIDQLPYVGLNLRRVLLNNETSMVNEGNNTRLLTLFKSMLSSEANAFVLDLEQYNNDLRVVDTTLLFSDVLIALQSFIFSTQNNLYANIIVLLLNISAPELDSTEYRHQNQTLNTTYILDKNLGNGFIYKPTDLQSDRAKNNTWNIYGKSSIDGWPTLGSVLYEQKKRLVIGELTDFFNETTAPYIFPHDVFHYEQGNSTLDCPSTVEGLTDLSSIHWRFLDSLFNSVDIKEYISCGLSPIISNSAYVNNVTQLADIIHEGSVWSWDSDQPSVTQSTSKSGSSSGTLEAYNCVLLYYFANNETVTWRVGNCYNSNIGLCRYENMAFRWLVRSNKATYFDFDSYQGSKCPDQYSFNIPRSPLEQRSFIAYMRNSSFSDTQIWIDLNSISVSNCWVSGGPYASCPYEKVISKRNFVTMMVPASVCSFALLCIVVYLSVLRVPIYDNRKNWRRVINKISKSELEGVPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: FPG_MAGMM
Sequence: MPELPEVETTRRGIEPALVGKRLCGVVVRQPQLRWPIPVKTLEKELVGQVIQQVARRAKYLLWRCPQGTLLVHLGMSGSLRIVPEHTPPAKHDHVDWVMEGGQMVRLHDPRRFGAVVWIPVTSPEEEHPLLAKLGPEPLHRSLNGRYLHQGSRGRQLAVKNYIMDQSVVVGVGNIYASEALFRAGIAPAQAAGKVGLGRYRALACAIKAVLGDSIEQGGTTLRDFIGSDGKPGYFVQSLNVYGRAGKACPKCGTTIEKQVLGQRSSYYCPQCQRA
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RS7_SOLM1
Sequence: MPRKGPVSKRSVLPDPKFGSHLMTKFINRLMHDGKKGVAENLFYQAVEVLAEKSGEDPLKAFEKAIGNVKPHMEVKPRRVGGATYQVPMEVRPERQVTLALRWLINQARARGEKGMADKLSGELLDAYHNRGGAVKKKEDTHRMADANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: BAEE_BACVZ
Sequence: MISFVFPGQGSQRIGMGEDLFGRYPELTAKADHILGYSIQELCRDGERLNQTQFTQPALYVVNALSYLKKTEETGLKPDFTAGHSLGEYNALYASGAFDFEEGLQLVKKRGELMSRAKGGGMAAVIGLTHEQVTDVLRENHLDMIDIANMNTPQQIVISGYKEDIEKAASVFEAVNGVKMVHRLNVSGAFHSRYMLEAKEEFSRFIESFHFKPLSIPVISNVTARPYEQRELKETLTGQITGSVNWTDSIRFLMGRKNMSFEEIGPGKVLTGLIQRITAEAEPITDEIKVPAEAGKSSITAASLGNEEFKRDYQLKYAYLAGGMYRGISSKEMVVKLAEKGMMGFFGTGGLNIAHVEDAILSIQHELRDGGSFGINVVHNMKHTDSEEKMIDLLLKHGIQNLEASAFLTVTPALVRFRAKGLKRGAGGQIIARQRIIAKLSRPEVAEAFLSPAPDHILQKLAAENKITAEEASLMREIPVAHDICVEADSGGHTDGGVAYSLMPAIIRLRDDMMKKYRYGKTVRIGAAGGIGTPEAAMAAFMLGADFIVTGSINQCTVEAATSGLVKDLLQQMNVQDTAYAPAGDMFESGSKVQVLKKGLFFPTRASKLHELYQRHRSIEEIDEKTLRQIEEKYFKASVSSIYDKVKAHYSNEDISKAERNPKEKMALIFKWYFRQSSASAIKGDPDAKVDFQIHCGPALGAFNQWVKGTELESWKNRHADGIGMRLMEETASLLNQKLGSFLQTC
What is the function of this protein?
Probably involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.  Probably has an acyl transferase activity and could also have a flavin mononucleotide-dependent oxidoreductase activity.
What are the official names of this protein?
Polyketide biosynthesis protein BaeE.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the FabD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXB8_MOUSE
Sequence: MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKEKLERAPETAEQGDAQKGDKK
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-B8, Homeobox protein Hox-2.4.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1195_STRPI
Sequence: MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLTGDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SPH_1195.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL6_LACH4
Sequence: MSRIGLKTIEVPDSVTVTKDGDNITVKGPKGELTRYFDPKITFEQKDGEINFSRSSESDKALHGTERANLASMIEGVVNGYKKTLKLIGVGYRAQAQGNKVTLNVGYSHPVVLTAPEGVTVKATSATDVEVEGVSKQDVGQFAAEIRAVRPPEPYKGKGIRYVDEYVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HMP2_CAEEL
Sequence: MLLHSTNSYSIFTDHEVETRTSRIRSAMFPDWIPPTSAAEATNSTTSIVEMMQMPTQQLKQSVMDLLTYEGSNDMSGLSLPDLVKLMCDHDESVVARAVHRAYMLSREDPNFFNAPGFDHRSFVEALMAASKSSNVNVRRNAIGALSHMSEQRGGPLLIFRSGGLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQARALNAVEALTPHLHKTNPKLLAQVADGLYFLLIDDAPSKITFLSLLGPQILVSILREYSDHRKLIYTVVRCIRSLSVCPSNKPALISLGCLPALYVELCTAKDERSQTAILVAMRNLSDSATNEENLTQLIIKLLEIIRVANDGMTACACGTLSNLTCNNTRNKQTVCSHGGIDALVTAIRRLPEVEEVTEPALCALRHCTARHSLAEEAQSELRFCQAFPVILDQLETLRTPVIKAALGVIRNSALLQTNLIELTQEQTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVIEGAVSALHQLANHPAVAAACCDDIGQVGNPECPPFLDLLHRLLAHPRLGSMDDEVLEREILGLLYQLSKRPDGARAVESTGVSALLMESRGSQYKSVVTYANGVLSNLKRGDSAAIMNMSNSYDYEMSGSAADWQRDGLERELFAEMYPTNDGGHSESINMALNNSQMRPNHNWYDTDL
What is the function of this protein?
Required for cell migration during body enclosure and cell shape changes during body elongation (PubMed:9531567).  Plays a role in recruitment of the cadherin protein hmr-1 to adherens junctions (PubMed:26412237).
What are the official names of this protein?
Beta-catenin-like protein hmp-2, Protein humpback-2.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction.
Protein: THIM_ACIBS
Sequence: MTSTSNLIEQVIEAWQNMQAKTPLVQCITNSVAANYTANVLLASGASPAMIDNPYEAESFTKISSALSINLGTPTSEQMQAMQISAKTAQLNNVPWVLDPVGYGPILAWRSQMTDELLQFKPSVIRGNASEISTLAGNQVQSKGVDSTLSSDQAYQQAYVLLAHADCIAISGESDYILSRELDAVIQVNGGSPLQPKITATGCALGALIAAYSAVTTPTIAALSAHIHFAIAGKLAANQAQTMGSFSSIFMDYIHMLDANLIEQYADIKLLDKQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.