PharMolix/UniProtQA huggingface dataset:
Protein: FIP1_EMENI
Sequence: MSHAMDDDDDDLYDPADAVPVTNPSDPRGPSADAPMNDNVEEEEEEVEEDDEDDFNIITEAPPDAPPPETSHPRHANLRTESQRPTSADSTSAQKSQTPTLTPKVDTSASVPAGTRPTSQKPGSAYPPVHASNIDVNANPVHPATGKPILMTDMDADFPDDDKPWRRPGTDLTDYFNYGFDEFTWASYVLKQQELRKEVGDQKRQLDDMQNFLTMGLPPMPGAQPGAGPAAVSAPPPMPGMPGIPDMNPDMMQGMLASMMSQGLDPSSMDPMSFMQHAQTMMGGQSGAGGGQQGQGGFGGQGGGQSQMGYGNAGGGYGGGRGRGRRW
What is the function of this protein?
Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.
What are the official names of this protein?
Pre-mRNA polyadenylation factor fip1.
What is the protein family that this protein belongs to?
Belongs to the FIP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_BACHK
Sequence: MDKKVTEVVEAFAQPIVEELNLELVDVEYVKEGQDWFLRVFIDSEKGVDIEECGAVSERLSEALDKEDPIPHLYFLDVSSPGAERPLKKEKDFQQAVGKQVAIKTYEPIDGEKMFEGKMLSYDGTTITLLLTIKTRKKEIQIPMDKVANARLAVTF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_PSEU2
Sequence: MTVKKVTRLRRARKARLKMHELEVVRLCVHRSSQHIYAQVISADGSKVLASASTLDKELRDGATGNIDAATKVGKLVAERAKAAGVSQVAFDRSGFKYHGRVKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: 3MGH_CARHZ
Sequence: MLLPRQFYARDVLIVAKDLLNCYLVREYNGHLLIGKIVETEAYHQNDPACHAYRGKTKRNEVMFGPPGHAYVYFTYGMHYCFNVVTGAIGRAEAVLIRALEPVKGIDIIKTLRGGKSERELLSGPAKLTQGLAIDLKLNGHDLTGGKILYITKGEPVAEEDIVVTTRIGINAGKDLPYRFYLKNNKYVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: VPS10_CANGA
Sequence: MRLPSIFLVFFYLFARTLCWSPEVSLLHGVDSLASIIPFDDSSTILSVGRKGVNVSHDYGRTWETKLRNKGEYPVSVTLNTFRPNSRAFVFLNGKLYGTHNEGSDWFESKFPSDRQLTKALTIDFSPFAKDVIIASFVAKDNQNDEKEFNYVSTDDGKSFRVLDVGQEYESMRCRFLSISHESNFPHNDNIICMTKTSSPDQNKLLLSENRGKSFKELSIGEDIAFDNFYLTNSYLVIRSIRDIHNKAAEVDLYVSSDAKDFKKAYLPTTLRRSDIRRIIELLGRKMFITLTRSSESNVQDDNGNTLFTDGLVSNSDGLKFTSFSTSASKSRTTITPVEFLNGTFIQKQVGRNSGGYSISIDNGNTWRKLKYSDKGNKNPIKCQDENDCNLELLIPQIFHGPTAGILVMLGHINDNFSDQQTFISRDGGLNWEMGLEFPGIYATGDLGNVIVACPVDPSSDNDPQSEIYYSLDQGMTWSEYQLDEMFIPIDVINITPDGSGLSFILTGFSLDKPDDQRPNIDNRVTYLIDFNNVHDGKKCKAKDYEKFELAEGSCINGAKYTFNRRKQSAKCIGGEVFKDLLFDMEVCTECQEQDYECSSEFIKDSKGVCVVDEKWLSATGNCPSTDIKKPAMRLIADNMCKKELPIQSKSVSCKNKNPSDPKDIPKKPKEGDRPTFGTGDIQATFNTFKGKVRFYQYFDTDEDESLILATSEGEAYISHDSGQTYTHFNYNKPKVHEIVFNEYFNSSAYIFDIDGNLHVTHDRGYTFDTIRLPASLQLGLPLNFHSKDPNTFIYYGGKNCKSIFDTNCHIVAFITRDGGKSFSELLPNAIHCEFVGSSLKLSDSDDLLFCQVKDETSSKTRQRSLVSTTDYFETEPKVVFQKILGYMTNGEYVIIAVPGENHEITAYVTMDGDEFAETLLPYDLDIEQPEAFTVLGSSTGSVFLHFTSFQENSVAFGSLLKSNTNGTSYVKLQSNVNRNEAGYVDFEKVQGLDGIILTNVVTNADEIKDGSSQKHLRTKITFNDGVDWEYIKPPKKDSSGDSYHCKSNKLEHCSLNLHSYTERKDFRDTFSSGSALGMMIGVGNVGDKLLPFEECSTFLTIDGGKSWTEIKKGAYQWEFGDHGGILILSRDGEMTNSISYSTDFGKSWYDYQFSDEKVLVSDIVTVPQDSALRFLLITADRIGRGFESGTVTVDFSGLFKRQCVLDFNNENHDDFDYFSIGNSENECIFGHKVKYLRKNSEECYVGAVSLSQFTRVMKNCTCTRADFECDYNFVRQYDGTCKLVDGLQPGNEAAICKKDPDLVEYFQSTGYRKIPLSTCQGGLKLDGRTEPLPCPGKEKEFKQKYGISGSSFFLLFFVPFLFFVSAGWFVYDRGIRRNGGFARFGEIRLGDDQLIEENTTDKVVNTIIRFGVASFEVMAGGFGIIRRIANNSFNRITGRMNGRYRPSYSNLMHDDFLDEADDLLAGHDDDANDLASFMDDDSNFDIEDETTSVNDSGYRDQSPETENVVDSNN
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Prevacuolar compartment membrane; Single-pass type I membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: SYC_RENSM
Sequence: MTLRFYDTATAEVRDFAPLVEGKASLYYCGATVQSEPHIGHLRSALVFDQLTRWLQFRGFQTTVVRNVTDIDDKILAKAAEAGEEWWARAYKYEQQFNAAYDKLGITRPDYEPRATGNISEMHSLIQDLIDRGHAYPAPDGSGDVYFDVRSWGKYGSLTHQNIDDMQAAADADPRGKKDARDFALWKGRKPEEPTTASWPSPWGAGRPGWHLECSAMVGKYLGDAFDIHGGGLDLRFPHHENEMAQSQAAGRPFANFWMHNGLVAYQGEKMSKSIGNVIGPGELFAQASPRVVRYYLGQAHYRSVLDYSPESLEEAAAALARIDGFLVNAGANVQRVEVEDSGHMYLPPAAKQGFGWFAYAPLSDTPAAFVEAMDDDLNVPKALAVLHETVRAGNSAIASSDLVELQKKFEAVLAMLDVLGLSSIATDQAADNGSTHALETLVQTRLQERQQARTEKNWARSDEIRDELAEAGIKIEDSSNGATWSIERKQQR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YGIB_SHIFL
Sequence: MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKYTDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
What are the official names of this protein?
UPF0441 protein YgiB.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: LEUC_CLOB8
Sequence: MGMTMTQKILAAHAGLEAVKAGQLIEANLDLVLGNDITTPVAVNEFKKFGTDKVFSKSQIAIVPDHFTPNKDIKAAEQVKYIREFAQNMEIENFFEVGEMGIEHCLLPEKGLVVAGDVVIGADSHTCTYGALGAFSTGIGSTDMAAGMATGKCWFKVPSALKFVLKNKPAKWISGKDIILHIIGMIGVDGALYKSMEFVGDGLQYLSMDDRFTMANMAIEAGGKNGIFPVDDKTEEYLKDHASREWKVYEADEDAEYDKVFEIDLSELRPTVSFPHLPDNTRTIDNTGDVAIDQVVIGSCTNGRISDLRMARDILKGKKVKKGIRCIVIPGTQKIYLQAIKEGIVTDLVEAGAAFSTPTCGPCLGGHMGILAKGERCVSTTNRNFVGRMGHVESEVYLASPAVAAASALTGKITDPELV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: PHLG_PSEPH
Sequence: MAAICQFTPKDISMEARNMTPFTYFSLPMQKLFLRNQAAVRNKPYAKYFRSEMRVPLSAVRKIQQGPMALEDTLTPSIEDINRLLEPDFVSEESGYALLPGPMAYVQSRKFFPGCTAQMFKWWFIWHPAESERYTLWFPYAHVSNPCVHHQRLCDESLSFEERLYGNTFCASEYVGDRLMHLHIDFQQPASLGLNTDLYREAKIDGSVSALMSLADHPEVPVSLMVHLFKEVPDGMYLTSRYWVGAHPSMARFPGAEKAASLLKENGFGEAELETLAYEFAVHDMCEFNHLASFLPDLYREFGTPAA
What is the function of this protein?
Hydrolase that specifically degrades the potent antimicrobial compound 2,4-diacetylphloroglucinol (DAPG) to equimolar amounts of mildly toxic monoacetylphloroglucinol (MAPG) and acetate.  Does not degrade other compounds with structures similar to DAPG, such as MAPG and triacetylphloroglucinol, suggesting strict substrate specificity (PubMed:16391073).  Degradation of DAPG to MAPG may provide an additional means of fine-tuning levels of this antibiotic or may help avoid accumulation of a metabolite that at high levels may become toxic to the producing bacterium (PubMed:16391073).
What are the official names of this protein?
2,4-diacetylphloroglucinol hydrolase, DAPG hydrolase.
What is the protein family that this protein belongs to?
Belongs to the DAPG/phloretin hydrolase family.
Protein: ATPG_CHLSY
Sequence: MPSSREIKRRIRSVKNVAQITRAMEMVSASKMRRAQRNVLATRPYADRMREVMANLTARVVGAARRGTLLEKRETVKSVALLVVTPDRGLCGSLVANVLRRAGRFITEQRAMGRTVDVYTFGRKGRDFFLRTGFAPAGEATRLGDAPKLEAILGVAISAINGFQSGKYDELYIIYSEFINTLVQRPAIKQLLPVESPDISTTTNVDYTYEPGEEEVLNSILPRYVETQIYQAVLESIASEHSARMVAMRNATNNAKDLVRDLTLSFNKARQAAITKEVSEIASGAAALTS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BIOB_ECO24
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RL32_CAMJJ
Sequence: MAVPKRRVSKTRAAKRRTHYKVSLPMPIKDKDGSYKMPHRANPTTKEY
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: IP3KC_MOUSE
Sequence: MRRCPCRGSLSEAEAGALPAEARMGLEALRGGRRRQPGLQRPGPGAGGPTGRPEGGGPRAWIEESSLHSEAERTDLEPAPCPNGPQAESCGDGHAECEAAGLVVASEKPRQNKELDGSNLQTHPRRNSPLVEMEMAGSWTDGFRTDLHRSDLQSRPKRASLCTQPGFDESWTELDRSDMWQTLPERDNKPRVDNLRTHHGVSKLQTHPVCLSPESSADNSGKELSADASRTPHDTDGFWIESQTDDSLKGPSTQTACRQPGSDGFSSKDTESALTQPGTDGLRDDSVLGESNGNDPLDLSEPGELVTNLCSHLECSSLCPVPRLIITPETPEPEAQPVGPQSRIEGGTGGFSSASSFDESEDDLVAGGGGTSDPEDRAGSKPWKKLKTVLKYSPFVVSFHKHYYPWVQLSGHAGNFQAGEDGRILKRFCQCEQRSLELLMGDPLRPFVPAYYGMVQRDGQAFNQMEDLLADFEGPSIMDCKMGSRTYLEEELVKARERPKPRKDMYEKMVAVDPGAPTPEEHAQGAITKPRYMQWRETLSSTSTLGFRIEGIKKADGTCNTNFKKTQALEQVTKVLEDFVNGDLGILRKYVARLEDLRETLENSPFFKTHEVVGSSLLFVHDHTGLAKVWMIDFGKTVALPDHQMLSHRLPWTEGNREDGYLWGLDNLICLLQGLAQS
What is the function of this protein?
Catalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis (By similarity).  Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate (By similarity).
What are the official names of this protein?
Inositol-trisphosphate 3-kinase C, Inositol 1,4,5-trisphosphate 3-kinase C, IP3 3-kinase C, IP3K C, InsP 3-kinase C.
What is the protein family that this protein belongs to?
Belongs to the inositol phosphokinase (IPK) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity.
Protein: ABCB7_ORYLA
Sequence: MAPMLVSLNCGIRVQRRTLTLLIRQTSSYHIWDKSCINNGTNYQRRRTYALNSLHPQRTASWSTNRTENRRQILEAAKHLQVTDKRTCWHGNAGGRLNADPKNVLKEVHSAKILSAMLSYVWPKDRPDLRARVAVSLGLLAGAKLTNVMVPFMFKYAVDELNQMSGHMLNLNDAPSTVATMTTAVLIGYGVSRAGSALFNELRNTVFGKVAQSSIRRIAKNVFLHLHNLDLGFHLSRQTGALSKAIDRGTRGISFVLSALVFNLGPTVFEMFLVSAILYYKCGGEFAAVALGTLSAYTIFTILVTQWRTRFRIEMNKADNEAGNAAIDSLLNYETVKYFNNEKYEAERYDGYLKLYESSSLKTTSTLAMLNFGQSAIFSVGLTAIMLLASKGIAAGNMTVGDLVMVNGLLFQLSLPLNFLGTVYRETRQALIDMNTLFTLLNVDTKIKEKDLAPPLAVTPQDATIRFEDVYFEYMEGQKVLNGVSFEVPAGKKVAIVGGSGSGKSTIVRLLFRFYEPQQGNIYISGQNIRDVSLESLRKALGVVPQDAVLFHNNIFYNLQYGNINATPEEVYQVARLAGLHDAILRMPHGYDTQVGERGLKLSGGEKQRVAIARAILKNPPILLYDEATSSLDSITEENIMTSMKEMVKDRTSVFIAHRLSTIVDADEILVLSQGKVAERGTHQALLDTPGSLYAELWNAQNSKILNSRKSSSAPAAERLSQKEEERKKLQEEILNSVKGCGNCSC
What is the function of this protein?
Exports glutathione-coordinated iron-sulfur clusters such as [2Fe-2S]-(GS)4 cluster from the mitochondria to the cytosol in an ATP-dependent manner allowing the assembly of the cytosolic iron-sulfur (Fe/S) cluster-containing proteins and participates in iron homeostasis (By similarity).  May play a role in iron and lipid metabolism (PubMed:19046159).
What are the official names of this protein?
Iron-sulfur clusters transporter ABCB7, mitochondrial, ATP-binding cassette sub-family B member 7, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Mitochondrion.
Protein: YIAF_ECO57
Sequence: MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNTVMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQDYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTPADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLPAQHQAFNQAWTTAVTATQ
What are the official names of this protein?
Uncharacterized protein YiaF.
Protein: HFQ_THEAB
Sequence: MAEKFNLQDRFLNILRTNKIPVKVYLVNGFQTKGIIRSFDNFTMLLENGSQQNLIYKHAVSTIMPESFVKLTKQQNEESENEEK
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: VE6_HPV24
Sequence: MAQPGKPQSVLELSRLLNIPLDDCVVPCNFCKRFLSYTELTDFDTKCLSLIWKDDFVFACCRYCCVATAAFEFENYFVESVIGWEIEQKENTPLSDIIVRCHHCLKLLNQIEKLDICGRSELFHKVRRGWKGLCRQCKQI
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: YR513_MIMIV
Sequence: MSDVTVTPSATSKLTGILKPGSYEIEKGHFSRYFSLNWWQLIVVVGIAISGIAAIANTYDAITGVDKDIEGCENVSNLRKKLEAKFIIIIVLSCLAVVGGIILAWLLRSGTNQRKLLTMGLTTGGILGILYALTIRFRGTSNMVKLGISWVSLLAFVLLGFFINTSGE
What are the official names of this protein?
Uncharacterized protein R513.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PNP_CAMJ8
Sequence: MQYSIEINKNTEIFDIDKVAKQAAGAVLMRQGKSVVLATVAREEKQVEEDFLPLTVQYIEKAYAAGKIPGGYVKRETKPSDAETLTARIIDRSLRPLFPKGYTYPTQIVVMVLSADPKVDLQVMSLNAASVALYLSDIPMKAPVCGVRIGKIDGNFILNPNNEELQNSTLDLYVAGVKDELLMIEMRALPDQKENEIFIEAPYADVLTQTTSQNMNELSEDEILEALNLAQKAILNGSNAYEEAFSKHKKNSQIELKNEIEHPEILAFIENNFQKQIKEAINQMAKSERASELNKIAKEILNLEIAKDWSEESVLNTLAKVKRKLIREQILNEGKRADGRSLNEVRPISIETNILPNAHGSCLFTRGQTQALVVATLGGENDAQMIDLLTEKNPISERFMVNYNFPGFSVGEASPIKAPGRRELGHGNLAKRALYPSVDENYPYVIRLVSEILESNGSSSMATVCGGSLALKAAGVPSLKLVAGVAMGLIFEDNKHAVLTDIMGLEDHDGDMDFKVAGSKDGVTALQMDIKLGGIDQETLKQALYQAKEGRIHILNIMEEAAKEIIVNEEVLPKLELFSVDPSKIVDIIGQAGKTIKEIIEKFGVSIDLDREKGEVKIAGSQNEQIKAAKDYIINITSSQKGTKKGSKDKDISGFELGQEFQGIVKKIAPFGAFVELKNGVDGLLHSSKSKHLNLTENQSLKVKISEIKNGKISVDLCE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_ECOSE
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVSRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAK0_YEAST
Sequence: MVLRRHKLLAQQRWLRVKFSDRSGRVFTLKNRNQLSIIMPFCVLHICFPLYKVTLECNLSNLLPHFSVSGLVNPFASKVLSEYFSFLSNNCTNILPILHLRLFYNIRCLGKQF
What are the official names of this protein?
Putative uncharacterized protein YAR030C.
Protein: SYT_OLEA2
Sequence: MKVSIEGSVVEVESGASCRDVLKQALSGKKFKKVLAARCGGTMLDLTATVPTACETLEPVYADSPEGLGLIRHSAAHVMADAVQRLFPGVKVTIGPAIENGFYYDFDYERPFTADDLEAIEAEMDKIIKAAHPFERSVMSKDEAKKMFADMGETYKLELIDAVPDDIVSIYRSGDFVDLCRGPHIPDTGCINAFKLMSVAGAYWRGDEKNAMLSRVYGTAFPDEKELKSYLNRIEEAKKRDHRKLGTQLDLFSFQEEGGSGMVYWHPKGALVRAILEDFERKEHLKRGYQIVQTPQILRRELWEKSGHYDNYRENMYFTDIDEQPYGVKPMNCVAHMLIYKSRSHSYRDLPVRLFELGVVHRHEKSGVLHGLLRVRQFTQDDAHIICTPDQLESEIVGVLNFVRDVMGVFGFEYSMEVSTRPEKSIGSDEDWDRATSALVKALEGQGLPYEINEGDGAFYGPKIDVKLRDCLGREWQCATVQCDFTLPDRFDLVYIGQDGERHRPVMVHRVILGSVERFIGVLTEHFAGAFPTWLAPVQARLLTVTDAQNEFAEEARAALMAQGIRVEVDTRNEKLGYKVREAQLEKIPYILVIGDKEVEARGVNVRLRKGDNLGLKTLDEVVDIIRADCEEPFKSGGMRYSFS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_ECO7I
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVKKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: LON_CALS8
Sequence: MMIAVTKRTIPVIPLRGLVVFPYMMLHFDVGRQISLKALEEAMNSDQQVLLLAQKDPKQEEPSPEDLYQYGTVAKIKQMLKLPSETSRILVEGLSRAKVIGYVSVDPYFLVEVEEYKEKGGNLDDPELEALIRNVVSAFEEYARLTSRIPPDAILSVTTIQNPGQLADVIAANVIVKLEDKQLLLEQVDLKERLTKLYELILREKEIIEIERKITIKVKKQIDKMQKEYYLREQLKAIQSELGEKDSLFSEAQEYREQVQKLGLSNENLQKVYKEIDRLEKLPPNSPEIGVIRTYLEWIIDLPWNVKSEEKIDINVVKNVLDEDHYGLTKVKERILEYIAVRKLKNNLKGPILCLVGPPGVGKTSIAKSIARALNRNYVRISLGGLRDEAEIRGHRKTYVGAMPGRIIYALRQAKTKNPLILLDEIDKMSQDFRGDPASALLEVLDSEQNYAFRDHYVEIPFDLSEVMFIATANTLETIPRPLLDRLEVIEITGYTEEEKVEIAKRYLFPKQIEQNGLKKSQIRYDEAVIRDIISFYTRESGVRNLEREIARLCRRVAKEILEENKKMVRITTRNLEKYLGVRKYRRDELIEEDRIGIVTGLAWTPFGGETLSVEALVMPGSGKLELTGQLGDVMKESAKAAVSIIRARAKELGIDENFYKEYDIHIHVPEGAIPKDGPSAGVTMATAMVSALSKKPVRHDVAMTGEITLSGRVLPIGGVKEKILAAKRVGIKNVILPYENKKDVDELEDYVKKDMNFVFVKAIDEVFKIAIKE
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_FLAJ1
Sequence: MSDIASRVKAIIVDKLGVDENEVVTEASFTNDLGADSLDTVELIMEFEKEFDIQIPDDQAENIATVGQAISYIEEAKK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_METTP
Sequence: MSLEIEKIHAREILDSRGNPTVEVDVWTCCGFGRAAVPSGASTGTYEALELRDGGDRYDGKGVLKAVRNVNEVIGPKLIGMDVIDQRGVDQIMIEMDGTPNKSNLGANAILGVSLAVAKAAASSLGMPLYRYLGGVSATRLPVPSLNVLNGGKHAGNDLSIQEFMIEPWGADSFSEALRMAAETYHALGRILRGKYGNVATNVGFEGGYAPPISKTRDALDAIMAALDVTGYTEEIKLGLDSAASSFYLDGGYSVDDNRLSPGELIDFYVELVKTYPIVLIEDPFEENAFEEFAELTKKLPDTIIVGDDLYVTNMARIEKGIRMRSTNALLLKLNQIGTVSEAFDAATLAYRNSFKVMVSHRSAETEDSALADVSVAIGAELIKTGAPARSERNAKYNQLLRIQEALGSSASYAGRRRWS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: HYP2_PISTI
Sequence: EIVSLSLSLLAVVPLVVLVIAGPLNVRGGTPSQQCNTGTPQCCQQVQQTSDLQQFRSSFGLVDALAGASALVGANCNPVSVLGTGNGAQCNTQPVCCTSNQMLGAVNMGCMPLNVNA
What are the official names of this protein?
Hydrophobin-2.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: NU2M_NEUCR
Sequence: MIIMTILSLLLSNAVTLRRDISILFNRIVIIALIYCILHDTMSLSIISKGVGLHGGLLHITNITQVFQIFIFLISILILQLTSFDPIKKFYIMRHPRFINKWPRAIGYSIPLSSIQAVLKDYLFKIQGFNKEHLKIIEYPLILLFVICGAVFLMSTNDLVSIFLSIELQSYGLYILSTIYRNSELSTTGGLIYFLLGGFSSCFILLGASLLYANSGTTSLDGLYIINSISDVNDNMTSWYKSYYLNFSLLIFSVGFLFKVSAAPFHFWSPDVYDAIPTIVTTFVAIIAKISIFILLLELVYHTNNYLSEFSWIYGLLVSSFLSLIIGTVVGLTQFRIKRLLAYSTISHLGFILLALSVSTQSVESTQAFIFYLIQYSFSNLNVFIILITIGFSLYGYVWNNKEYKNLLDINNSPVQLISQLKGYFYLNPLLSLSLAITIFSFAGIPPLVGFFAKQMVLSAALDNGYIFLSLIAILTSVVGAVYYLNIIKEIFFYSPGHKLKTVDVENTWPFPVKRDLKLNDSNAFSISYDRYTVSSPLSSGYTISSPFSITISIITIVILLFIFMNKEWLSMGTIMVQVLFST
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.