PharMolix/UniProtQA huggingface dataset:
Protein: MSS1_SCHPO
Sequence: MRILNRVFLNTFQACFRRFVHQIPTIYALSTPPGTSAVAIVRISGPNACKVAKTLAGSVPKPRIASLRTIKHPVRSEVIDKALMLYFKKPSSFTGEDVVELQLHGGTAVVDVTLEAIKQSGIPNIRYAKPGEFSERAFYNGRADLTQLEGLIDVINAQTAEQLYSANKEAHGSIYDICFRWRKKLIEYRAFLEASIDFSEEHELDDIETIKLFEELNEMKDEIDAHIEGGKCKEVLRKGINVAILGPSNAGKSSLINLLANRRISIVSPQSGTTRDAIEVLVDINGFPVLLSDTAGLRKGEDVQEIEKIGIEIAKARAEESQLTLFVFPINYHSFSESLKQSEILETIKDCLRQRKPIHFLINKVDCVSDYTTMFKPIKAYLQKNFLIPENRIHAVSCKTKEGLIDFLQALSSTFECMVNPLTNNKIQANLGWNERQRQCLSSCSSHLSLALQKSSDIVVAAEEVKLATEDIGRVTGAVDMENVFSVIFSKFCVGK
What is the function of this protein?
GTPase involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.
What are the official names of this protein?
tRNA modification GTPase mss1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: UTP14_YEAST
Sequence: MAKKKSKSRSKSSRRVLDALQLAEREINGEFDNSSDNDKRHDARRNGTVVNLLKRSKGDTNSDEDDIDSESFEDEELNSDEALGSDDDYDILNSKFSQTIRDKKENANYQEEEDEGGYTSIDEEDLMPLSQVWDMDEKTAQSNGNDDEDASPQLKLQDTDISSESSSSEESESESEDDEEEEDPFDEISEDEEDIELNTITSKLIDETKSKAPKRLDTYGSGEANEYVLPSANAASGASGKLSLTDMMNVIDDRQVIENANLLKGKSSTYEVPLPQRIQQRHDRKAAYEISRQEVSKWNDIVQQNRRADHLIFPLNKPTEHNHASAFTRTQDVPQTELQEKVDQVLQESNLANPEKDSKFEELSTAKMTPEEMRKRTTEMRLMRELMFREERKARRLKKIKSKTYRKIKKKELMKNRELAAVSSDEDNEDHDIARAKERMTLKHKTNSKWAKDMIKHGMTNDAETREEMEEMLRQGERLKAKMLDRNSDDEEDGRVQTLSDVENEEKENIDSEALKSKLGKTGVMNMAFMKNGEAREREANKETLRQLRAVENGDDIKLFESDEEETNGENIQINKGRRIYTPGSLESNKDMNELNDHTRKENKVDESRSLENRLRAKNSGQSKNARTNAEGAIIVEEESDGEPLQDGQNNQQDEEAKDVNPWLANESDEEHTVKKQSSKVNVIDKDSSKNVKAMNKMEKAELKQKKKKKGKSNDDEDLLLTADDSTRLKIVDPYGGSDDEQGDNVFMFKQQDVIAEAFAGDDVVAEFQEEKKRVIDDEDDKEVDTTLPGWGEWAGAGSKPKNKKRKFIKKVKGVVNKDKRRDKNLQNVIINEKVNKKNLKYQSSAVPFPFENREQYERSLRMPIGQEWTSRASHQELIKPRIMTKPGQVIDPLKAPFK
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 14, U3 snoRNA-associated protein 14, U three protein 14.
What is the protein family that this protein belongs to?
Belongs to the UTP14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ALLT_SPOFR
Sequence: MNISMHLAVAVAAAACLCVCAAAPENRLARTKQQRPTRGFKNVEMMTARGFGKRDRPHTRAEHQDSYDSHARRKFNPKSNLMVAYDFGKRSGNDDVTDEVYGLDNFWEMLEATPEREGQENDEKTLESIPLDWFVNEMLNNPDFARSVVRKFIDLNQHSFGLVRERDAEQSRFRAICGPQVH
What is the function of this protein?
Neuropeptide stimulator of juvenile hormone synthesis.
What are the official names of this protein?
Allatotropin, AT, Spofr-AT.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGB_ECOLI
Sequence: MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYCB_ECOLI
Sequence: MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEKESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGSRPLDIPANANTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCPTKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK
What is the function of this protein?
Probable electron transfer protein for hydrogenase 3.
What are the official names of this protein?
Formate hydrogenlyase subunit 2, FHL subunit 2, Hydrogenase-3 component B.
Protein: SYFB_GEOKA
Sequence: MLVSYRWLGEYVDLTGITAKELAERITKSGIEVERVEALDRGMKGVVIGHVLECEPHPNADKLRKCLVDLGEDEPVQIICGAPNVAKGQKVAVAKVGAVLPGNFKIKRAKLRGEESNGMICSLQELGVETKVVPKEYADGIFVFPSDAPIGADAIEWLGLHDEVLELSLTPNRADCLSMIGVAYEVAAILGRDVKLPEAAVKENSEHVHEYISVRVEAPEDNPLYAGRIVKNVRIGPSPLWMQARLMAAGIRPHNNVVDITNYILLEYGQPLHAFDYDRLGSKEIVVRRAKAGETIITLDDVERKLTEEHLVITNGREPVALAGVMGGANSEVRDDTTTVFIEAAYFTSPVIRQAVKDHGLRSEASTRFEKGIDPARTKEALERAAALMSEYAGGEVVGGIVEASVWRQDSVVVTVTLERINGVLGTAMSKEEVAAILSNLQFPFTEDNGTFTIHVPSRRRDIAIEEDIIEEVARLYGYDRLPATLPVAEAKPGGLTPYQAKRRRVRRYLEGAGLFQAITYSLTSPDKATRFALETAEPIRLALPMSEERSVLRQSLIPHLLEAASYNRARQVENVALYEIGSVYLSKGEHVQPAENERLAGVLTGLWHAHLWQGEKKAADFYVAKGILDGLFDLFGLAARIEYKPAKRADLHPGRTAEIALGGKVIGFVGQLHPAVQKEYDLKETYVFELALTDLLNAESEAIRYEPIPRFPSVVRDIALVVDENVEAGALKQAIEEAGKPLVKDVSLFDVYKGDRLPDGKKSLAFSLRYYDPERTLTDEEVAAVHERVLAAVEKQFGAVLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGD_MYCTU
Sequence: MTGASTTTATMRQRWQAVMMNNYGTPPIALASGDGAVVTDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGHTSNLYATEPGIALAEELVALLGADQRTRVFFCNSGAEANEAAFKLSRLTGRTKLVAAHDAFHGRTMGSLALTGQPAKQTPFAPLPGDVTHVGYGDVDALAAAVDDHTAAVFLEPIMGESGVVVPPAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDGITPDVVTLAKGLGGGLPIGACLAVGPAAELLTPGLHGSTFGGNPVCAAAALAVLRVLASDGLVRRAEVLGKSLRHGIEALGHPLIDHVRGRGLLLGIALTAPHAKDAEATARDAGYLVNAAAPDVIRLAPPLIIAEAQLDGFVAALPAILDRAVGAP
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA2_PSEAE
Sequence: MFSKHDQLQGYDDELLAAMDAEDRRQEDHIELIASENYASKRVMQAQGGGLTNKYAEGYPGKRYYGGCEHVDKVERLAIDRARQLFGADYANVQPHSGSSANAAVYLALLNAGDTILGMSLAHGGHLTHGAKVSSSGKLYNAVQYGLDTATGLIDYDEVERLAVEHKPKMIVAGFSAYSKTLDFPRFRAIADKVGALLFVDMAHVAGLVAAGLYPNPIPFADVVTTTTHKTLRGPRGGLILARANEEIEKKLNSAVFPGAQGGPLMHVIAAKAVCFKEALEPGFKDYQAQVIRNAKAMAEVFIGRGYDVVSGGTDNHLMLISLVKQGLTGKAADAALGAAHITVNKNAVPNDPQSPFVTSGIRIGTPAVTTRGFREGECRELAGWICDILDDIDNPEVGERVRGQVGEFCRHFPVYAD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase 2, SHMT 2, Serine methylase 2.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRK_LEPBJ
Sequence: MSMPGINVSNLLNEHEELGLRLLAGEKGLTNRINMSEINRPGLSLTGFYESFAHDRIQIFGKGEWAYITSRIPEDLKNIAADFFSFHLNCIIFTHGNMPPPIFTENCERLAIPLMISDVSTHKFITLISGILDRSLAPRTMRHGVLIEVFGIGILLSGKSGVGKSETALELIERGHRLVADDMVEIRRLSESYLIGTCSDLLRHHMEIRGLGILNIKDIFGIGSVRDHKLIELIIRLEEWTEDKDFDRTGLENPTEELLGVQIPLIRVPVKPGRNIPIIVETAAMNQRLRKLGKNAAQEFNQKLSNYLQQGKVERNPP
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: RSXD_SALTY
Sequence: MVFRIASSPYTHNQRQTSRIMLLVLIAALPGIAAQTWFFGWGTLFQIVLAAITALVAEAIVLRLRKQSVASHLQDYSALLTGLLLAVSIPPLAPWWMVVLGTGFAIIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPYEIAATTPDMLDTLRMIFTGHTASGGDMTLLRIGIDGISQATPLDTFKTSLRAGHSVEQIMQYPIYSGALAGVGWQWVNLAWLVGGVFLLWQKAIRWHIPVSFLLTLALCAALGWLFSPATLASPQLHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGVLVWLIRSFGGYPDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit D, Rsx electron transport complex subunit D.
What is the protein family that this protein belongs to?
Belongs to the NqrB/RnfD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CP1A4_CHICK
Sequence: MAAGPQAAMEQASSPGLISATEVLVAAATFCLLLLLTQTRRQHAPKGLRSPPGPRGLPMLGNVLELRKDPHLVLTRLSRKYGDVMEVTIGSRPVVVLSGLETIKQALVRQAEDFMGRPDLPSWQYVSNGHSLAFSYECGDAWKARRKLAQNALKTFSIAASPTASSSCLLEEHVSTEASYLVTKFLQLMEEKQSFNPNSYLMVSVANVICAICFGKRYDHDDQELLSVVNMNTEFGDVAAAGNPADFIPLLRYLPNRAMAAFKDVNARFSAFVQKIVQNHYSTFDKEHIRDVTDSLIGHCQEKRTGEDVRVQPSDESIISIVNDLFGAGFDTVTTALSWCMMYAALYPHIQKKIQAELDQTIGRERRPRLSDRGMLPYTEAFILEAFRHSSLLPFTIPHCTTKDTVLNGYYIPKDTCVFINQWQANHDEKIWKDPPSFKPERFLNAAGTELSRTEADKVLIFGLGKRRCIGESIGRWEVFLFLTTILQQLEISLAPGQRVDITPQYGLTMKYKQCECFQMKKRFPSKGSA
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 1A4, CYPIA4, Cytochrome P450 TCDDAHH.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TF2B_PYRAB
Sequence: MTKQRVCPVCGSTEFIYDPERGEIVCARCGYVIEENIVDMGPEWRAFDASQREKRSRTGAPESILLHDKGLSTDIGIDRSLTGLMREKMYRLRKWQSRLRVSDAAERNLAFALSELDRITAQLKLPKHVEEEAARLYREAVRKGLIRGRSIESVIAACVYAACRLLKVPRTLDEISDIARVEKKEIGRSYRFIARNLNLTPKKLFVKPTDYVNKFADELGLSEKVRRRAIEILEEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQREVAEVARVTEVTVRNRYKELVEKLGIKVPVT
What is the function of this protein?
Stabilizes TBP binding to an archaeal box-A promoter.  Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
What are the official names of this protein?
Transcription initiation factor IIB, TFIIB.
What is the protein family that this protein belongs to?
Belongs to the TFIIB family.
Protein: OL478_MOUSE
Sequence: MAFQEDGNHTAVTEFVLFGLTDDPVLRVILFIIFLCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLAFADIGYSSSVTPNMLVNFLVERHTISYIGCAIQLGSVVFFGSSECFILAAMAYDRFMAICNPLLYSTKMSTQVCVQLLLIAYIGGFLNTWSFTICFYSLVFCGPNGVNHFFCDFAPLIELSCSDVSVPATVPSFTAGSIIVVTVIVIAISYIYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTITFIYVMPKSSFSTDQNKVVSVFYMVVIPMLNPLIYSLRNNEIKGALKRQIGRKIFS
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 478, Olfactory receptor 204-13.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3409_BRUC2
Sequence: MDDKVETGNIDVRLLELLVCPLTKGPLEYDAERSELVSRKARLAYPVRGGIPIMLPSEARSLTE
What are the official names of this protein?
UPF0434 protein BCAN_B0909.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: NADD_CLOTE
Sequence: MKKKAIFGGTFDPIHNGHLHIAYKALNRLKLDKIIFIPSGNPPHKHKECITDKNIRYNMVKYAIEQEDKFEISDYEVKKKGKSYTYETIEHFRKYHPNIDLYFIAGADCLMDIHKWKNIDSMMEKAKLVVFSRPGFSMDTILFQKKQVEEKFKKDIIFLDIPLLDVSSTEIREKIKKGEDIKDLIPEKTYNIIKKYGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: PMBA_BUCBP
Sequence: MMKLSDITTQENDLKKIVEYILNLAANHSVFSEVVIEKNCGVDVLIRKNSVNSIEFNKNNILTITVYKNNRKGMVSSTDLSFKSIHNVFSSVMGIVFYSSPDEFSGLPDRKLLAINKVKDLDLYHDWDWNINHAIEIAKLSEREAFKEDKRIINSEGSCFNSLVRTRAFGNSLGMIECYSTTLYSTSCCVIAGDNGDMQRDFSFSVSRDMNDLNLPEKVGQDSAKKALSRLNSKKLLTMKTSAIFSSEIAFEFFINFAKAINGNNVYQKSTFLLHSLNTQVFPNWLTIEERPHIKKGLSSKCFDAEGVMTKTKKIVNKGILKTWLLDTYSARKINLVSTGNSGGIHNWLILGNSNEGLQSLLKSMNTGLLITELLGQGVSITTGNYSRGAVGFWVDQGVIKYPVNEITISGNLKNMFKDIVSIGNDIDKRHSIQSGSILLSQIQVSGI
What is the function of this protein?
Probable metalloprotease.
What are the official names of this protein?
Metalloprotease PmbA homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase U62 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM40_HUMAN
Sequence: MTASVLRSISLALRPTSGLLGTWQTQLRETHQRASLLSFWELIPMRSEPLRKKKKVDPKKDQEAKERLKRKIRKLEKATQELIPIEDFITPLKFLDKARERPQVELTFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQLESPKLHAEAIKRDPNLFPFEKEGPHYTPPIPNYQPPEGRYNDITKVYTQVEFKR
What are the official names of this protein?
39S ribosomal protein L40, mitochondrial, L40mt, MRP-L40, Mitochondrial large ribosomal subunit protein mL40, Nuclear localization signal-containing protein deleted in velocardiofacial syndrome, Up-regulated in metastasis.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL40 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HIS4_CORGL
Sequence: MTFTILPAVDVVNGQAVRLDQGEAGTEKSYGTPLESALKWQEQGAKWLHFVDLDAAFNRGSNHEMMAEIVGKLDVDVELTGGIRDDESLERALATGARRVNIGTAALEKPEWIASAIQRYGEKIAVDIAVRLEDGEWRTRGNGWVSDGGDLWEVLERLDSQGCARFVVTDVSKDGTLSGPNVELLREVAAATDAPIVASGGISVLEDVLELAKYQDEGIDSVIIGKALYEHKFTLEEALAAVEKLG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCH_CAEEL
Sequence: MPSTSMIEDRSEIERRRFEYLDHPADIQLHSWGSTMEEAFEACLVSMFGYMTDLAKVDEMYEFYWKASGDSLDGLLFQFLDEALNSFHAEPCFVAKRVEILRFDKKKFEIEFRGWGESFDTSKHETEADIKSPTYSNMQINEKPERCDIYVIVDI
What is the function of this protein?
Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RtcB (F16A11. 2).
What are the official names of this protein?
Protein archease-like.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: DIA2_DICDI
Sequence: MKQIIRLITTLLLLSLIGITCAAVAKLHETDKKFKGVELPEKFLDDFNLEVGKLQYANLFRSKKDDITHSAGEIRIDQQGSFSRGEKKKKFKVYNLQAQTNGKSSKTVAHVEVFDTIDAKTKAEQNEVLALAKEAFTKSKDSGKLYQVIPN
What is the function of this protein?
Has an essential role in the initiation of differentiation.  Also required for cAMP signaling.
What are the official names of this protein?
Differentiation-associated protein 2, DIA-2.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Vacuole. Note=During late development it changes it's location from endoplasmic reticulum to pre-spore-specific vacuoles.
Protein: GLO2_PROM3
Sequence: MEATSTAATSDKQRSSIHALPVLQDNIIWIWIKGDQAVVVDPAIAEPVKTWLQTRKLSLAAVLQTHHHADHIGGTLELLRDWPNAAVVAAADDRDRIPFQTISVRDRDKISLLNSSVEVLAVAGHTRAHIAYYLPTNKEDREDPAVFCGDTLFGAGCGRLFEGTAEDMFKALQRLCCLPAKTRVYCAHEYTEANLRWASALHPEDIAISERLVDVSSRRQRGALSLPSSISEEQRTNLFVRAQNSKELAELRQHKDQWRN
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: MUG84_SCHPO
Sequence: MTLTHHSTFIKGIEGSAEGEIEDVRQTTVFDPPFYGHPMLVPPSPSLTTMFRTRSTTPDEEGTAIAEIDQQDWDIMVKVPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSSLECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 84 protein.
Protein: AAD3_YEAST
Sequence: MIGSASDSSSKLGRLRFLSETAAIKVSPLILGEVSYDGARSDFLKSMNKNRAFELLDTFYEAGGNFIDAANNCQNEQSEEWIGEWIQSRRLRDQIVIATKFIKSDKKYKAGESNTANYCGNHKRSLHVSVRDSLRKLQTDWIDILYVHWWDYMSSIEEFMDSLHILVQQGKVLYLGVSDTPAWVVSAANYYATSYGKTPFSIYQGKWNVLNRDFERDIIPMARHFGMALAPWDVMGGGRFQSKKAMEERRKNGEGIRSFVGASEQTDAEIKISEALAKIAEEHGTESVTAIAIAYVRSKAKNFFPSVEGGKIEDLKENIKALSIDLTPDNIKYLESIVPFDIGFPNNFIVLNSLTQKYGTNNV
What are the official names of this protein?
Putative aryl-alcohol dehydrogenase AAD3.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: MTNB_SALSA
Sequence: MTSVCDATNEDKENGSESTESQDKEHPRVLIPELCRLFYQLGWVTGTGGGLSLRRGDQIYIAPSGVQKERLQPDDMFVCDVEERDISSPPPWKKLKKSQCTPLFMNAFTMRAAQAVIHTHSKAAVMATLFYPGKEFRITHQEMIKGIRKGTSSTNYRYDETLVVPIIENTPEERDLKERMALAMEQYPDSCAVLVRRHGVYVWGESWEKAKTMCECYDYLFDIAVQMKQSGMDPSAPPIEENHYYDVQQSQ
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).  Functions in the methionine salvage pathway.  May play a role in apoptosis.
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase, APAF1-interacting protein homolog.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYNS_SYNY3
Sequence: MAGTEISAITTKLLEAKKAKGITFADLEQLLGRDEVWIAAVIYRQASASVDEAEKLLHCLGLSDDLVPELTAPSVKGLGPVVPTDPLIYRFYEIMQVYGMPMKEVIHEKFGDGIMSAIDFTLDIEKEADPKGDRVKVTMNGKFLPYKKW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: FOLD_NEIMB
Sequence: MSAQLINGKEVSQKRLQAVAEAVAQRQQNNLHHPCLAVVLVGGDPASAVYVRNKKTACQKCGIKSLSYELPESTSQEELLALVDRLNADSEVDGILVQLPLPKHLDSQAVLERISPDKDVDGFHPYNVGRLAVKMPLMRPCTPKGVMTLLEAYGIDPKGKKAVVVGASNIVGRPQALELLLARATVTVCHSATENLTDEVAGADILVVGVGIPNFVKGEWIKPGAVVIDVGINRLDDGSLCGDVEFETAKERAAMITPVPGGVGPMTIATLMENTLHAASLHDA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HIS1_SYNE7
Sequence: MLTIALPKGALLKDSIRLLQSAGLDFSAFLEPGNRQLQILDRQERAKALLVRNSDVPVYVEYGQAQLGVVGYDVLREKTARVAQLIDLRFGGCRMSIAVKASSPYRSVLDLPAHCRIASKFVHCARDYFHNLDLPVEIVPLSGSVELGPITGMSEAIVDLVATGQTLRENGLVEIETLFDSTARLIANPLAYRINADGISELIEELRQSVTQAIAATC
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S47A2_MOUSE
Sequence: MEPAEDSLGATIQPPELVRVPRGRSLRILLGLRGALSPDVRREAAALVALAGPVFLAQLMIFLISIVSSIFCGHLGKVELDAVTLAVSVVNVTGISVGTGLASACDTLMSQSFGGKNLKRVGVILQRGILILLLCCFPCWAIFLNTERLLLLLRQDPDVARLAQVYVMICIPALPAAFLFQLQTRYLQSQGIIMPQVIVGIAANVVNVGMNAFLLYALDLGVVGSAWANTTSQFFLSALLFLYVWWKRIHIHTWGGWTRECFQEWSSYTRLAIPSMFMVCIEWWTFEIGTFLAGLVNVTELGAQAVIYELASVAYMVPFGFGVAASVRVGNALGAGNADQARCSCTTVLLCAGVCALLVGILLAALKDVVAYIFTNDKDIISLVSQVMPIFAPFHLFDALAGTCGGVLRGTGKQKIGAVLNTIGYYGFGFPIGVSLMFAAKLGIIGLWAGLIVCVSFQAFSYLIYILRTNWSRVAEQAQVRAGLKSTKELIPTPADLPILEREVMDGVILPDIIRPESQTGQLVVEENSQCAVPTVGEVLTGRQLVFYRGMALTVSVAVLIAGIVVRVFNDRG
What is the function of this protein?
Multidrug efflux pump that functions as a H(+)/organic cation antiporter (PubMed:17715386).  May mediate testosterone efflux from the Leydig cells in the testes (PubMed:17715386).
What are the official names of this protein?
Multidrug and toxin extrusion protein 2, MATE-2, mMATE-2, H(+)/organic cation antiporter kidney-specific, Solute carrier family 47 member 2.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Localized to the plasma membrane and to the intracellular organelles.
Protein: DB126_GORGO
Sequence: MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCVPADRRANYPAFCVQTKTTRTSTVTATTATTTLMMTTASMSLMAPTPVSPTG
What is the function of this protein?
Highly glycosylated atypical beta-defensin involved in several aspects of sperm function.  Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx.  Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation.  Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte.  In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (By similarity).
What are the official names of this protein?
Beta-defensin 126, Defensin, beta 126.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted by epididymal cells and is absorbed to the surface of sperm during transit through the epididymis.
Protein: PVR_HUMAN
Sequence: MARAMAAAWPLLLVALLVLSWPPPGTGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEVTHVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDEGNYTCLFVTFPQGSRSVDIWLRVLAKPQNTAEVQKVQLTGEPVPMARCVSTGGRPPAQITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLTVNLTVYYPPEVSISGYDNNWYLGQNEATLTCDARSNPEPTGYNWSTTMGPLPPFAVAQGAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISRNAIIFLVLGILVFLILLGIGIYFYWSKCSREVLWHCHLCPSSTEHASASANGHVSYSAVSRENSSSQDPQTEGTR
What is the function of this protein?
(Microbial infection) Is prevented to reach cell surface upon infection by Human cytomegalovirus /HHV-5, presumably to escape immune recognition of infected cell by NK cells.
What are the official names of this protein?
Poliovirus receptor, Nectin-like protein 5, NECL-5.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
[Isoform Alpha]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform Delta]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform Beta]: Secreted. SUBCELLULAR LOCATION: [Isoform Gamma]: Secreted.