PharMolix/UniProtQA huggingface dataset:
Protein: GB_MUHVS
Sequence: MSRRNERGCRSSSWYAMSTALAVTIWCLLACTSEVIAAASTPGTTPKAKTDTSSETASAETETATSGAATGKKEATPTQASKITGTTIVPFVNETEDMVSVDIDKYPYRVCMAVSTDLVRFGKSIDCINHTPKTPVQEGIMVVYKENIVAYTFEVITYHKDAIFQRSYADTTTNYFLGTSVTKMAFPIWELDEVNRNNRCYSAASRILNGEVYVAYHEDSYRNYTMVLVEDDYRSKNSKRYVTTKSRYHKGAWTWRYTESCNMNCVVVVTKARSNTPYEFFVLSSGEVVEISPFYNGENSEPFEEDTRNFWIRKNYTMKTYFGELAAPKKVVPLMAFLEREDMTIGWEIFPKQNVTCDWKKWQTVSRAIRTDTNTGYHFVSKGLTATFVASKRKIDYNTTTEGKNYNTFRCVYDEFVEEVNRVFEDEYNETHVKDGELEMYRTTGGLIVLWQGLKAKSLHNLEKFAALNNVSVATASPPVTTAATENGTTVRSRRKRSFDNLDDVVTDISYAQLQFTYDVLKDYINDALRNIMDAWCRDQKRTAEMLKELSKINPSNILSAIYERPVTAKLAGDVIAMSECVKVDQSSVKVLKDMRIFQDGKVVNCYSRPLVVFQFINSTKLESGQLGENNEIMLGTFRTENCDTNSRKIFVVGTVGYEYRDYRFRNVTSLEHIDLVDTLIGLDIEPLENTDFKVLELYSKGELRASNVFSLDEIMREYNSQKQHIRTLSAKVNDNTPSYLLGLDTFMQGLGVAGKGIGVAIGAVGGAVSSVVNAVTGFLTNPFGGFTTILLVIGVLAVVYLIFTRPVEYFFPYATQTAVQYAPPGGAHGGLESGPPGAPGLHRRVNAGGSDDSGKAWTSDKKGLERTYTEQDALLILRALKQLDDSQRNEKAQQKATRLPTGILDRLKGNDTSGYQRLPAEDSDFEY
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: PYRE_THEP1
Sequence: MIKEILEKTGALMEGHFILSSGKHSSRYVQCARLFEFPEYGDIVGEELAKLLRKYDVETVVGPAMGGVILSYVVARYLKARSLFAERENGVMKLRRGFFVRPGEKAAVVEDVVTTGGSVKEVIELLKEYGANVVCVGSIIDRSGGKVDFGVPFESLLKLDLPVYDPEDCPLCKQGIPAEKPGSRGLK
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: RL4_RHOBA
Sequence: MANLPILDASGKEVGQYEIDTEQIANRVSKQLLHDVVVMYQANKRQGSHNTRTRGQVSGTNKKMYRQKGTGNARAGSKRTNVRRGGGVARTVKPRDYSYRLPKKAIKIATRMAIRSRIDDGEIVVINELKLDAPKTSQIAQILKNLGLANTTTLIATAGDDQIIYKSGRNISGVTVEPVRQLNALTLLTPKRVLFTQEALDRVKDGTFAGSTQNTNEAEAAA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: DHAS_SHESP
Sequence: MSQEFNVVVLGASGAVGQTIIEILQERNFPIAKLFPLASSRSAGGTVSFNGKQVEILDVDDFDWSQAQIGFFSAGGDVSEKWAPIAAESGCVVIDNTSHFRYDNDVPLVIPEVNPEAIADFRNRNIIANPNCSTIQMLVALKPIYDAFGISRINVATYQSVSGSGKEAIAELAGQCSKLLQGLPIEPKVYSKQIAFNVLPQIDTFMENGYTKEEMKMVWETQKIFGDDNIVVNPTAVRVPVFFGHSEAIHLETIQPAEAEDVKAVLRDAPGIELFESNEEYPTAVTESAGTDPVYVGRVRKDISHSHGINLWVVSDNIRKGAALNSVQIAEVLIRDYY
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: NQO8_PARDE
Sequence: MAEFWASPYGFALSMLLQGLAVIAFVMGSLIFMVYGDRKIWAAVQMRRGPNVVGPWGLLQTFADALKYIVKEIVIPAGADKFVYFLAPFLSMMLALFAFVVIPFDEGWVMANINVGILFIFAASSLEVYGVIMGGWASNSKYPFLASLRSAAQMISYEVSLGLIIIGIIISTGSMNLTAIVEAHGGDYGLLNWYWLPHLPMVVLFFVSALAECNRPPFDLVEAESELVAGFMTEYSSTPYLLFMAGEYIAMYLMCALLSLLFFGGWLSPVPFIADGWWWMVIKMWFWFYMFAMVKAIVPRYRYDQLMRIGWKVFLPLSLGWVVLVAILARYEILGGFWARFAVGG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 8, NADH dehydrogenase I subunit H, NDH-1 subunit 8.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GCN5_YARLI
Sequence: MDSDTESVKRRKSSGSESESSVRDPKRTKIEDEDFQENGIDDEDEEEEEEEAKDEGDEDDEEKGEDDEEDDEEKEGEDGEGEEEDEEEDEEKKREEEEKYVTSFNFDGVEYKYKERPAVIEEREGKIEFRVVNNDNSKENLMILTGLKNIFQKQLPKMPREYIARLVYDRSHVSMAVVRKPLTVVGGITFRPFDTRKFAEIVFCAISSTEQVRGYGAHLMNHLKDYVKATSPVMYFLTYADNYAIGYFKKQGFSKEISLDRSVWMGYIKDYEGGTLMQCSMLPRIRYLDVNKILLLQKALIHKKIRAISKSHVVRKGLDHFRDSTTPVDPMTIPGLKEAGWTPEMDELARRPKRGPHFAVMQHVLSELQNHASAWPFAQAVNRDEVPDYYEVIKEPMDLSTMEQRLEADSYKTMEEFVYDARLVFNNCRAYNNETTTYYKNANKLEKFMVAKIKEIPEYSHLVE
What is the function of this protein?
Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, with a lower preference histone H4 to form H4K8ac and H4K16ac, and contributes to H2A. Z acetylation.  Acetylation of histones gives a specific tag for epigenetic transcription activation (By similarity).
What are the official names of this protein?
Histone acetyltransferase GCN5.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GCN5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAN14_HUMAN
Sequence: MSLWPPFRCRWKLAPRYSRRASPQQPQQDFEALLAECLRNGCLFEDTSFPATLSSIGSGSLLQKLPPRLQWKRPPELHSNPQFYFAKAKRLDLCQGIVGDCWFLAALQALALHQDILSRVVPLNQSFTEKYAGIFRFWFWHYGNWVPVVIDDRLPVNEAGQLVFVSSTYKNLFWGALLEKAYAKLSGSYEDLQSGQVSEALVDFTGGVTMTINLAEAHGNLWDILIEATYNRTLIGCQTHSGEKILENGLVEGHAYTLTGIRKVTCKHRPEYLVKLRNPWGKVEWKGDWSDSSSKWELLSPKEKILLLRKDNDGEFWMTLQDFKTHFVLLVICKLTPGLLSQEAAQKWTYTMREGRWEKRSTAGGQRQLLQDTFWKNPQFLLSVWRPEEGRRSLRPCSVLVSLLQKPRHRCRKRKPLLAIGFYLYRMNKYHDDQRRLPPEFFQRNTPLSQPDRFLKEKEVSQELCLEPGTYLIVPCILEAHQKSEFVLRVFSRKHIFYEIGSNSGVVFSKEIEDQNERQDEFFTKFFEKHPEINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQEFRDLWKQLKLSQKVFHKQDRGSGYLNWEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQMDFVSFIHLMLRVENMEDVFQNLTQDGKGIYLQKPEWMMMALYS
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease.
What are the official names of this protein?
Calpain-14, Calcium-activated neutral proteinase 14, CANP 14.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: ZAPA_SALHS
Sequence: MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKVRTRVTNTEQLVFIAALNISYELTQEKAKTRDYAASMEQRIRMLQQTIEQALLDQGRITEKTGQNFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: MNLOX_GAETR
Sequence: MRSRILAIVFAARHVAALPLAAEDAAATLSLTSSASSTTVLPSPTQYTLPNNDPNQGARNASIARKRELFLYGPSTLGQTTFYPTGELGNNISARDVLLWRQDAANQTATAYREANETFADITSRGGFKTLDDFALLYNGHWKESVPEGISKGMLSNYTSDLLFSMERLSSNPYVLKRLHPTKDKLPFSVESKVVKKLTATTLEALHKGGRLFLVDHSYQKKYTPQPGRYAAACQGLFYLDARSNQFLPLAIKTNVGADLTYTPLDDKNDWLLAKIMFNNNDLFYSQMYHVLFHTIPEIVHEAAFRTLSDRHPVMGVLNRLMYQAYAIRPVGGAVLFNPGGFWDQNFGLPASAAIDFPGSVYAQGGGGFQAGYLEKDLRSRGLVGEDSGPRLPHFPFYEDAHRLIGAIRRFMQAFVDSTYGADDGDDGALLRDYELQNWIAEANGPAQVRDFPAAPLRRRAQLVDVLTHVAWVTGGAHHVMNQGSPVKFSGVVPLHPAALYAPIPTTKGATGNGTRAGLLAWLPNERQAVEQVSLLARFNRAQVGDRKQTVRDAFAAPDLLAGNGPGYAAANARFVEDTGRISREMAGRGFDGKGLSQGMPFVWTALNPAVNPFFLSV
What is the function of this protein?
Lipoxygenase that metabolizes linoleic and alpha-linolenic acids to 11S- and 13R-hydroperoxy fatty acids.  At the end of lipoxygenation, the intermediate product 11S-HPODE from linoleic acid is then transformed into 13R-HPODE as the final product.  It also acts on alpha-linolenic acid producing 11S-HPOTrE and 13R-HPOTrE with subsequent transformation of 11S-HPOTrE to 13R-HPOTrE as the final product.  Gamma-linolenic acid is a poor substrate.  Oleate and arachidonate are not substrates.
What are the official names of this protein?
Manganese lipoxygenase, Mn-LO, MnLOX, Linoleate 11S-lipoxygenase, Linoleate 13R-lipoxygenase, Manganese 13R-lipoxygenase, 13R-MnLOX.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
Protein: ISPG_RHIE6
Sequence: MSSAADFDPKPRRASIAVDVGGVIVGGGAPIVVQSMTNTDTADIDSTVAQVAALHRAGSELVRITVDRDESAAAVPKIRERLLRLGMDVPLIGDFHYIGHKLLADHPDCAAALAKYRINPGNVGFKDKKDKQFAEIIEMAIRYDKPVRIGVNWGSLDQDLLTALMDQNAAAGSPLSARQVTREAIVQSALLSAALAEEIGLPRNRIILSAKVSQVQDLIAVNSMLAERSNHALHLGLTEAGMGSKGIVASAAAMGFVLQHGIGDTIRVSLTPEPNGDRTREVQVAQEILQVMGFRQFVPVVAACPGCGRTTSTVFQELAQNIQNDIRKNMPVWREKYPGVEALNVAVMGCIVNGPGESKHADIGISLPGTGETPAAPVFIDGKKALTLRGPNIAADFEALVVDYIEKRFGQRTAAE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: DBP8_SCHPO
Sequence: MSEHTRKSFSDLGISPWLIDTLKALAIYEPTDIQEGVIAQILEGRNCIGGAKTGSGKTAAFALPIIEKWSKDPSGIFALILTPTRELAIQIDEQFAALGANLNLKHALIVGGMDMIRQSIDLSKRPHVVVATPGRLADLIRSNGEETIAGLRRIKFLVMDEADRLLSPTFADDLDDCFSVLPASEDRQTLLFTATVTDAIRQLKYQPQKNNKPPLWLYEVETDNISVPSTLQQSYIFVSSQVREAYLVHLLTIPENAKKSAIIFVNRTRTAELIYSILRLLELRVTELHSEMVQRERINSLGRFRAEAAKILVATDVASRGLDIPSVQLVINFDLPRDPDDYIHRVGRTARAGRSGESISIVTERDVDLVHAIEDRVGTKLSEYEHVSENKMLEYIKEVTDAKRQASLEMIDRGFGERRQKRNEKRLMANGISNKLKNSGRKKKAKNTLSTEK
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase dbp8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GCS2_HALVD
Sequence: MELGSADAFDRMGTLGVEEEFYIVDADGRPTSGIDDLVYGPEPPEPLAGRLDHELFQFTIETQTPLIEDPDEAGAAVSTVREALVDHAAAHGYRIAAAGLHPAAKWRELDHATKPRYQAQLDRIQYPQHRNTTAGLHVHVGVDDADKAVWVANELRWYLAPLLALSANSPFWNGFDTGLASARAKVFENLPNTGMPTAFDDFEEFQRFERRMVEYGSIDDRGELWYDVRPHTGHGTVEIRTPDAQTDPERVTDFVEYVHALVLDLADRYEAGESGTSVRRELLDENKWRATRYGRDTDFIAPDSEGVVSLVSFVETESDRLGVDGLRSLLDAESGTAVQRRIHEESGLDGLCEHLTLD
What is the function of this protein?
Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC), the main low-molecular-weight thiol compound instead of glutathione in halophilic archaea.
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-glutamylcysteine synthetase, GCS, Gamma-GCS.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: GP46_LEIAM
Sequence: MAQCVRRLVLAAPLAAVVALLLCTSSAPVARAAGTSDFTGAQQKNTLTVLQAFARAIPALGDTWTGSDFCSWEHIICYSSGVGVWMHNVDYTGTLPEMPASVDYKDVMILALDFGAMGQGLSGTLPPSWSSMKHLIVLDLEGTKVSGTLPPEWSEMTSAEALQLENCGLSGSLPTSWSSMPKLRIVSLSGNHFCGCVPDSWREKDRLDVTIEEWHMGEDCKLANACRPTAAPGTTTTNPPTTTGTPAASSTPSPGSGCEVDGCEVCEGDSAARCARCREGYSLTDEKTCLGEPRWRRGGGVERTAGCRCCVGGCAVERGAGGVRVRRAPLLCGAPGACPRPRHGVVAALSPPPADGETDSHTRTRTRRRASRVLSAVVAPARMHGHAEACMRVRVPALVCLSVWPAVGTRRRSNVRAAAVCRLGQRRCGARPSPCASVCVSWPRERRTECACPALFDGARLRCCALVVCAGAAPAG
What are the official names of this protein?
Surface membrane glycoprotein GP46/M-2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: RL7A_METS5
Sequence: MAKPSYVKFDVPPELAEKALEALKKAKETGKIRKGTNEATKAIERGQAKLVLIAEDVQPEEIVAHLPPLCEEKKIPYIYVPTKKGIGEACGLQVGAAAAAILDPGQGKDVLDEVIKRVSELTGKS
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BEV1F_BETPN
Sequence: MGVFNYEIEATSVIPAARLFKAFILDGDNLFPKVAPQAISSVENIEGNGGPGTIKKISFPEGFPFKYVKDRVDEVDHTNFKYSYSVIEGGPVGDTLEKISNEIKIVATPNGGSILKINNKYHTKGDHEVKAEQIKASKEMGETLLRAVESYLLAHSDAYN
What is the function of this protein?
May be a general steroid carrier protein.
What are the official names of this protein?
Major pollen allergen Bet v 1-F/I, Allergen Bet v I-F/I.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GP15_BPT7
Sequence: MSKIESALQAAQPGLSRLRGGAGGMGYRAATTQAEQPRSSLLDTIGRFAKAGADMYTAKEQRARDLADERSNEIIRKLTPEQRREALNNGTLLYQDDPYAMEALRVKTGRNAAYLVDDDVMQKIKEGVFRTREEMEEYRHSRLQEGAKVYAEQFGIDPEDVDYQRGFNGDITERNISLYGAHDNFLSQQAQKGAIMNSRVELNGVLQDPDMLRRPDSADFFEKYIDNGLVTGAIPSDAQATQLISQAFSDASSRAGGADFLMRVGDKKVTLNGATTTYRELIGEEQWNALMVTAQRSQFETDAKLNEQYRLKINSALNQEDPRTAWEMLQGIKAELDKVQPDEQMTPQREWLISAQEQVQNQMNAWTKAQAKALDDSMKSMNKLDVIDKQFQKRINGEWVSTDFKDMPVNENTGEFKHSDMVNYANKKLAEIDSMDIPDGAKDAMKLKYLQADSKDGAFRTAIGTMVTDAGQEWSAAVINGKLPERTPAMDALRRIRNADPQLIAALYPDQAELFLTMDMMDKQGIDPQVILDADRLTVKRSKEQRFEDDKAFESALNASKAPEIARMPASLRESARKIYDSVKYRSGNESMAMEQMTKFLKESTYTFTGDDVDGDTVGVIPKNMMQVNSDPKSWEQGRDILEEARKGIIASNPWITNKQLTMYSQGDSIYLMDTTGQVRVRYDKELLSKVWSENQKKLEEKAREKALADVNKRAPIVAATKAREAAAKRVREKRKQTPKFIYGRKE
What is the function of this protein?
Component of the cylindrical core that assembles on the inner surface of the capsid during capsid formation and plays a role in viral DNA ejection into the host cell.  The inner core is composed of stacked rings of gp14, gp15 and gp16 proteins.  Following binding to the host cell surface, the internal core is disassembled and gp15 is ejected along with gp14 and gp16 into the infected cell.  Gp15 probably remains associated with gp16.  The gp15-gp16 complex binds to both the viral DNA and the host inner membrane, probably escorting the leading end of the genome through the periplasm and controlling the extend of DNA translocated into the host cell.
What are the official names of this protein?
Internal virion protein gp15, Gene product 15, Gp15.
What is the protein family that this protein belongs to?
Belongs to the T7virus internal virion protein gp15 family.
What are the subcellular locations of this protein?
Virion. Host periplasm. Note=The gp15-gp16 complex spans the periplasm and the cytoplasmic membrane.
Protein: RBFA_SHEON
Sequence: MAKEFSRTRRIGQQLQQELAVVLQRDMKDPRIGFVTVNDVDVSRDLSYAKVFVTFFEEDKDVVQEKLNALIAAAPYIRTLVAGRMKLRVMPEIRFVYDSSLVEGMRMSNLVSQVINSDKAKQQQFGSVDDDVIENDIEESDDTEGKV
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIQ_VIBVY
Sequence: MLTLQQVHYYYHQDLFAFDLEVEAGSIVALMGPSGAGKSTLLALLAGFIAPQSGQMALDGRLLNTLSPAQRPFSMLFQEHNLFAHLTVRDNIALGLHPGLKLTSQQQKQVEQAAKQVGIEAYLDRLPEQLSGGQRQRVALARCFVQPNPIWLLDEPFSALDPVLRDEMLSLVKQLAQERAITVLMVTHHLSDARAIASHFAYIDKGTIAAHGPIASLNEKHSHPELVEFFQAAV
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLME_PSYA2
Sequence: MATRIENKKLSKSSSAWMKEHIDDHYVQKAQKDGYRARAAYKLLEINEKTNLIKKGMTVVDLGSAPGSWSQVAGQLVGEKGILIASDILPMDTLPDVTFIQGDFREPEVFDHIMAEVGDRQVDVVLSDMAPNTAGNSAIDQPRMMYLCELAVDFALATLPEGGALIMKVFQGEGTQELRKQMQADFSKIRSIKPGASRPRSKEMFWIAIK
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_BACSU
Sequence: MSEEKQTVEQNETEEQEIIEEQAAADEQQEETNESELLQNQINELQGLLEEKENKLLRVQADFENYKRRSRLEMEASQKYRSQNIVTDLLPALDSFERALQVEADNEQTKSLLQGMEMVHRQLVEALKKEGVEAIEAVGQEFDPNLHQAVMQAEDENYGSNIVVEEMQKGYKLKDRVIRPSMVKVNQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB_STRCO
Sequence: MEANTRSTGRLPAAFLTPGSSSFMDFLGEHQPEMLPGNRQLPPVQGVIEAPHGTTIVAVTFPGGVVLAGDRRATMGNMIAQRDIEKVFPADEYSAVGIAGTAGLAVEMVKLFQLELEHFEKVEGAQLSLEGKANRLSTMIRSNLGMAMQGLAVVPLFAGYDVDRGRGRIFSYDVTGGRSEERHFATTGSGSVFARGAMKKLFRDDLTEEQATTLVVQALYDAADDDSATGGPDVARRIYPIITVITEDGFRRLGEDEAAELAGSVLQARLEQPDGPRAALL
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.  The S. coelicolor proteasome is able to cleave oligopeptides after hydrophobic residues, but not after basic or acidic residues, thus displaying chymotrypsin-like activity but not trypsin-like activity.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S10A6_HORSE
Sequence: MACPLDQAISLLVAIFHKYSSREGDKNTLSKGELKELIQKELTIGAELEDSEIAKLLDDLDQNKDQVVNFQEYVTFLGALAMIYNEVLKACS
What is the function of this protein?
May function as calcium sensor and modulator, contributing to cellular calcium signaling.  May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility.  Binds 2 calcium ions.  Calcium binding is cooperative (By similarity).
What are the official names of this protein?
Protein S100-A6, Calcyclin, S100 calcium-binding protein A6.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: URED_LACP7
Sequence: MTNYTGYLQLSTEKKRGKTIAQDMYFYGAFKLMNPFYLNNDEQACFYIMNPGGGYVDGDTYRMDIHLAKEAQLLLTTQSASKIYKTPKNPVVQEINITLKEGSLLEYLPDPIIGYKNSRYKQKTIVHMEKGTSLIATDIITSGWDPKGNLFSYHMLDLNTKVYLEDNLILLDHIRLTPGSQSLSSIGQFEEYSHLGTMIVVSEYTDESLISMLYDVMETQNLKCRYGLSMLSKPGFMLRVLASSTQEVMRAFDICHKLIRMKWYKRSPVFLGKY
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_AERS4
Sequence: MQLNSTEIAELIKQRIAQFDVKSEARNEGTIVSVSDGIIRIHGLADAMQGEMIELPGNRFALALNLERDSVGAVIMGSYDGLSEGMKVKGTGRILEVPVGRGLLGRVLNTLGQPIDGKGPVENDGFSPIEVIAPGVIERKSVDQPVQTGLKAIDAMIPIGRGQRELIIGDRQVGKTAIAIDTIINQKDSGIKCVYVAIGQKASTIANVVRKLEEHGALANTIVVVASASEAAALQYLAPYAGCSMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAARVNAEYVEKFTNGAVKGQTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLTSQLFNSGIRPAVDPGISVSRVGGAAQTKIVKKLSGGIRTALAQYRELAAFAQFSSDLDEATRKQLDHGVKVTELMKQKQYSPMSVAQQSLVLFAAEKGYLSDVELNKIVDFEAALLSYANTQHAELMAEINAKADYNDAIVGKLTALLDDFKATQTW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: URE2_KOCRD
Sequence: MTPGEYVLADTPVVCNAGREAITLEVLNRGDRPVQVGSHFHFAEANRALDFDRERATGHRLDIPAGTAVRLEPGDSTTVRLIPLGGDRVVHGFRDLVDGPLDPAAGVTSDEDAASAVVPRGAETSEREARA
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_ECOUT
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLSTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.