PharMolix/UniProtQA huggingface dataset:
Protein: ARP2_SCHPO
Sequence: MESAPIVLDNGTGFVKVGYAKDNFPRFQFPSIVGRPILRAEEKTGNVQIKDVMVGDEAEAVRSLLQVKYPMENGIIRDFEEMNQLWDYTFFEKLKIDPRGRKILLTEPPMNPVANREKMCETMFERYGFGGVYVAIQAVLSLYAQGLSSGVVVDSGDGVTHIVPVYESVVLNHLVGRLDVAGRDATRYLISLLLRKGYAFNRTADFETVREMKEKLCYVSYDLELDHKLSEETTVLMRNYTLPDGRVIKVGSERYECPECLFQPHLVGSEQPGLSEFIFDTIQAADVDIRKYLYRAIVLSGGSSMYAGLPSRLEKEIKQLWFERVLHGDPARLPNFKVKIEDAPRRRHAVFIGGAVLADIMAQNDHMWVSKAEWEEYGVRALDKLGPRTT
What is the function of this protein?
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.  Seems to contact the pointed end of the daughter actin filament (By similarity).  During cytokinesis it colocalizes to the cortical actin patches until spetation is complete.  Has a role in the mobility of these patches.  Essential for viability.
What are the official names of this protein?
Actin-related protein 2, Actin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch.
Protein: PLAS_PHOLA
Sequence: MKLIAQISRSLSLALFALVLMVGSFVAVMSPAAAETFTVKMGADSGLLQFEPANVTVHPGDTVKWVNNKLPPHNILFDDKQVPGASKELADKLSHSQLMFSPGESYEITFSSDFPAGTYTYYCAPHRGAGMVGKITVEG
What is the function of this protein?
Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I.
What are the official names of this protein?
Plastocyanin.
What is the protein family that this protein belongs to?
Belongs to the plastocyanin family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Loosely bound to the thylakoid inner membrane surface (PubMed:10089349).
Protein: Y3752_PSEU2
Sequence: MLNYLWFFLAALFEIFGCYAFWLWLRQGKSALWVIPALVSLTVFALLLTRVEAAYAGRAYAAYGGIYIVASIAWLGLVERVRPLGTDWLGLAFCVIGATIILLGPRWSAA
What are the official names of this protein?
UPF0060 membrane protein Psyr_3752.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBX2_SCHPO
Sequence: MDGDEASLVANFCAITNSTPEKAQEYLSVADGDLSTAITLFFESGGVTDVQSSYIEAPSQTEPVEEIRAPIAPTREVLVDPLADMSAGTSIMGNNFGFGGFPRMNRRQRRRMGIFDQSPSQIPFPSSNTEDSSEESDSSSRASRLAKLFRPPYDIISNLSLDEARIEASSQKRWILVNLQTSTSFECQVLNRDLWKDESVKEVIRAHFLFLQLLDDEEPGMEFKRFYPVRSTPHIAILDPRTGERVKEWSKSFTPADFVIALNDFLEGCTLDETSGRKNPLGAKSQKPVEAMSEDEQMHKAIAASLGNGNSTTESQGESSSQQAESHGVADDTVHKIDSAECDAEEPSPGPNVTRIQIRMPNGARFIRRFSLTDPVSKVYAYVKGVAEGADKQPFSLTFQRKSLWTSLDSTIKEAGIQNTALQFEFQ
What is the function of this protein?
Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway.
What are the official names of this protein?
UBX domain-containing protein 2.
Protein: Y1445_METJA
Sequence: MSMRKIYLISDTHFNHANIIKYCNRPFSNVEEMNKTLIKNWNNVVRDKDIVYFLGDLILSKNKAKKARELLELLNGEIVFIRGNHDKFGEKFRVIEYNGYKFMLIHNPDSSYTLNFDGWIIHGHHHANHLDEYPFINPKRKSINVSVEVINYKPVSLDLIVKLIEKGKVVRTINDL
What are the official names of this protein?
Uncharacterized protein MJ1445.
Protein: CSPH_ECOLI
Sequence: MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEVLIPGLRVEFCRVNGLRGPTAANVYLS
What are the official names of this protein?
Cold shock-like protein CspH, CSP-H.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_BRUME
Sequence: MSKWKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQGEELEPARKKAEMLGIKEIFIEDVREEFVRDFVFPMFRANAVYEGVYLLGTSIARPLISKHLIDIAKKTGADAIAHGATGKGNDQVRFELSAYALNPDIKIIAPWRDWSFKSRTQLLEFAEQHQIPVAKDKKGEAPFSVDANLLHSSSEGKVLEDPSQEAPEYVHMRTISPETAPDKATIIKIGFEKGDAVSINGERLSPATLLAKLNDYGRDNGIGRLDLVENRFVGMKSRGVYETPGGTILLAAHRAIESITLDRGAAHLKDELMPRYAELIYYGFWFSPEREMLQAAIDHSQRHVEGEVTLKLYKGNVMVIGRESAKSLYSDKLVTFEDDQGAYDQKDAAGFIKLNALRLRTLAARDRK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTP2_CAEEL
Sequence: MTPTKPKVYIVGVGMTKFCKPGSVPGWDYPDMVKEAVTTALDDCKMKYSDIQQATVGYLFGGTCCGQRALYEVGLTGIPIFNVNNACASGSSGLFLGKQIIESGNSDVVLCAGFERMAPGSLENLAAPIDDRALSVDKHISVMSETYGLEPAPMTAQMFGNAAKEHMEKYGSKREHYAKIAYKNHLHSVHNPKSQFTKEFSLDQVINARKIYDFMGLLECSPTSDGAAAAVLVSEKFLEKNPRLKAQAVEIVGLKLGTDEPSVFAENSNIKMIGFDMIQKLAKQLWAETKLTPNDVQVIELHDCFAPNELITYEAIGLCPVGQGHHIVDRNDNTYGGKWVINPSGGLISKGHPIGATGVAQAVELSNQLRGKCGKRQVPNCKVAMQHNIGIGGAGVVGLYRLGFPGAAQSKI
What is the function of this protein?
Catalyzes the thiolytic cleavage of 3-ketoacyl-CoA with 8-16 carbon residues in the acyl group using a ping-pong mechanism whereby binding to 3-ketooctanoyl-CoA results in the release of acetyl-CoA and the subsequent addition of CoA produces 3-ketohexanohyl-CoA (PubMed:9151950).  Involved in the biosynthesis of the dauer pheromone by providing short chains of fatty acid that are attached to the ascarylose sugars of the pheromone (PubMed:19496754, PubMed:19174521).
What are the official names of this protein?
Non-specific lipid-transfer protein-like 2, NSL-TP2, 3-keto-acyl-CoA thiolase, Abnormal dauer formation protein 22, Propanoyl-CoA C-acyltransferase, Protein P-44.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Peroxisome. Note=Punctate localization in the cytoplasm.
Protein: ZN250_HUMAN
Sequence: MAAARLLPVPAGPQPLSFQAKLTFEDVAVLLSQDEWDRLCPAQRGLYRNVMMETYGNVVSLGLPGSKPDIISQLERGEDPWVLDRKGAKKSQGLWSDYSDNLKYDHTTACTQQDSLSCPWECETKGESQNTDLSPKPLISEQTVILGKTPLGRIDQENNETKQSFCLSPNSVDHREVQVLSQSMPLTPHQAVPSGERPYMCVECGKCFGRSSHLLQHQRIHTGEKPYVCSVCGKAFSQSSVLSKHRRIHTGEKPYECNECGKAFRVSSDLAQHHKIHTGEKPHECLECRKAFTQLSHLIQHQRIHTGERPYVCPLCGKAFNHSTVLRSHQRVHTGEKPHRCNECGKTFSVKRTLLQHQRIHTGEKPYTCSECGKAFSDRSVLIQHHNVHTGEKPYECSECGKTFSHRSTLMNHERIHTEEKPYACYECGKAFVQHSHLIQHQRVHTGEKPYVCGECGHAFSARRSLIQHERIHTGEKPFQCTECGKAFSLKATLIVHLRTHTGEKPYECNSCGKAFSQYSVLIQHQRIHTGEKPYECGECGRAFNQHGHLIQHQKVHRKL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 250, Zinc finger protein 647.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS19_BRUSU
Sequence: MARSVWKGPFVDGYLLKKAEKVREGGRNEVIKMWSRRSTILPQFVGLTFGVYNGNKHVPVSVSEEMVGHKFGEFAPTRTYYGHGADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ESPA_MYCTO
Sequence: MSRAFIIDPTISAIDGLYDLLGIGIPNQGGILYSSLEYFEKALEELAAAFPGDGWLGSAADKYAGKNRNHVNFFQELADLDRQLISLIHDQANAVQTTRDILEGAKKGLEFVRPVAVDLTYIPVVGHALSAAFQAPFCAGAMAVVGGALAYLVVKTLINATQLLKLLAKLAELVAAAIADIISDVADIIKGILGEVWEFITNALNGLKELWDKLTGWVTGLFSRGWSNLESFFAGVPGLTGATSGLSQVTGLFGAAGLSASSGLAHADSLASSASLPALAGIGGGSGFGGLPSLAQVHAASTRQALRPRADGPVGAAAEQVGGQSQLVSAQGSQGMGGPVGMGGMHPSSGASKGTTTKKYSEGAAAGTEDAERAPVEADAGGGQKVLVRNVV
What is the function of this protein?
Required for secretion of EsxA (ESAT-6) and EsxB (CFP-10) and for virulence.
What are the official names of this protein?
ESX-1 secretion-associated protein EspA.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-1 / type VII secretion system (T7SS).
Protein: INS_OCTDE
Sequence: MAPWMHLLTVLALLALWGPNSVQAYSSQHLCGSNLVEALYMTCGRSGFYRPHDRRELEDLQVEQAELGLEAGGLQPSALEMILQKRGIVDQCCNNICTFNQLQNYCNVP
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LGI1_RAT
Sequence: MESESIRRMGNACIPLKRIAYFLCLFSVVLLTEGKKPAKPKCPAVCTCSKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSPKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIDTQLYVIVAQLFGGSHIYKRDGFANKFIKIQDIEVLKIRKPNDIETFKIEDNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIARPPLTLRTPHLILSSSSQRPVIYQWSKATQLFINQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA
What is the function of this protein?
Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity).  Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1.  It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit.  Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors.
What are the official names of this protein?
Leucine-rich glioma-inactivated protein 1.
What are the subcellular locations of this protein?
Secreted. Synapse.
Protein: GYP6_YEAST
Sequence: MKDVLQWAIDHYETRDQLVQKGIWKGELYHDSIFKENSRGWLWKALLLCDENNNCLLTDNFKGLDLNQFGLVPVPMLADGDNYDENHNANVPKRVLHSNVSSSVGIRRLTPVEAVEKHPLSDDNDKTKGSLSKGSDEKPLTLRETLEIIDLDLSRIMLDDIFQEPKVHAQMRQLLYNYLLIHQSEHLQYKQGFHEILSVIYLQLYHGTDLDNTDLQNVLIIFNKLMNQIEPIFYNEENLINWDKRVFTKIFRICLPDLFSKVFYQPPKTGSGKKKNVDHLIHSNLIWLIRWTRLLFLRELPLKYVLIVWDHVLTFNYPLDIFIACTIITLLLSIYDELHELVSQGDYEHTNNNDEFVELILHFKKIFEKEDASKDDEKFLDLCKVTGNLCELWYGKNYDDMRLICDTFINAKFGIKTSDVLSMETAKLTIDPNRQSLENKLRERVRQTILKNKKKISQ
What is the function of this protein?
Stimulates specifically the GTPase activity of YPT6.
What are the official names of this protein?
GTPase-activating protein GYP6, GAP for YPT6.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HAOX1_MOUSE
Sequence: MLPRLVCISDYEQHVRSVLQKSVYDYYRSGANDQETLADNIQAFSRWKLYPRMLRNVADIDLSTSVLGQRVSMPICVGATAMQCMAHVDGELATVRACQTMGTGMMLSSWATSSIEEVAEAGPEALRWMQLYIYKDREISRQIVKRAEKQGYKAIFVTVDTPYLGNRIDDVRNRFKLPPQLRMKNFETNDLAFSPKGNFGDNSGLAEYVAQAIDPSLSWDDITWLRRLTSLPIVVKGILRGDDAKEAVKHGVDGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIIWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLAVSKI
What is the function of this protein?
Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate (PubMed:9891009).  The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones (By similarity).  Can also catalyze the oxidation glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate (By similarity).  Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2 (PubMed:9891009).
What are the official names of this protein?
2-Hydroxyacid oxidase 1, HAOX1, Glycolate oxidase, GOX, Glyoxylate oxidase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: ALLC_STRAW
Sequence: MTAQHPSPSARFTGDANPYGGGDPYADYRTADFPFTQYANLADRQLGAGVIAANDEFFAQRENLLVAGRAEFDPEHFGHKGKIMDGWETRRRRGASAAHPWPTAEDHDWALVRLGAPGVVRGVVVDTAHFRGNYPQAVSVEGASVPGSPSPEELLAGDVKWMTLVPRTAVGGHAANGFEVSVEQRFTHLRVNQHPDGGIARLRVYGEAVPDPVWLAALGTFDVVALENGGRVEDASNLFYSPATNTIQPGRSRQMDDGWETRRRRDHGNDWIRYQLVARSEIRAIEIDTAYLKGNSAGWAAVSVKDGESGEWTEILPRTRLQPDTNHRFTLAAPVAGTHARVDIFPDGGISRLRLFGSLTEEGAARLTARYQELGG
What are the official names of this protein?
Probable allantoicase, Allantoate amidinohydrolase.
What is the protein family that this protein belongs to?
Belongs to the allantoicase family.
Protein: HMOX2_HUMAN
Sequence: MSAEVETSEGVDESEKKNSGALEKENQMRMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDHPAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDLNMKTKERIVEEANKAFEYNMQIFNELDQAGSTLARETLEDGFPVHDGKGDMRKCPFYAAEQDKGALEGSSCPFRTAMAVLRKPSLQFILAAGVALAAGLLAWYYM
What is the function of this protein?
Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron.
What are the official names of this protein?
Heme oxygenase 2, HO-2.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
Protein: DTWD1_XENTR
Sequence: MSHEKSESCLQEKKHSSSFERFHDGTSLENNLLQNLKLSSQRVLEIAQKKGRSKCPKCNSSRMFYCYTCFVPVESVPSDEIPVVKLPLKIDIIKHPNETDGKSTAVHAKLLAHEDVTVYTYPCVPQYQDQKHEVVLVFPGPDSVSLSDSLLYIRGSGDMQNDSSCEPSLKRPKCSQQYDKSKNEGVEEKKPMHFLKKLIFIDSTWNQTNKIISDERLQGLQQVELMERKTCFWRHQKGTPNTYLSTIEAIYYFMIDYHTIILQKDYKGEYDDLLFFFSFMYRIINDAKKSAGKL
What is the function of this protein?
Catalyzes the formation of 3-(3-amino-3-carboxypropyl)uridine (acp3U) at position 20 in the D-loop of several cytoplasmic tRNAs (acp3U(20)).
What are the official names of this protein?
tRNA-uridine aminocarboxypropyltransferase 1, DTW domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. DTWD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: METAS_ESCF3
Sequence: MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTRTDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLNPDVPYNYFPHNDPQNTPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1144_THESQ
Sequence: MYGLINIGFGNVVAGDRVIAIVNPESSPLKRMKDEAKLEGKLIDATYGRKTRSIIITDSNHIILSAIQPETIAQRFMENFYEIERVLRETKK
What are the official names of this protein?
Putative regulatory protein TRQ2_1144.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: SYFB_BURP1
Sequence: MQFPESWLRTFVDPQLTTDELSHALTMAGLEVESLRPAAPPTEKIVVGRVLEVVKHPDADKLNVCQVDAGTGATLQIVCGAPNVAPGIKVPVALVGAKLPPAEEGGAPFAIKLSKLRGVESQGMLCSARELKLSEDHSGLMILPEGTPVGQDIREALNLDDTVFEIKLTPNKADCLSVFGIARETAAITGAPLAAPDIRPVLAELTETLPVKISAPDLCGRFSGRVIRGVNARAKTPHWMVERLERAGQRSVSALVDISNYVMFELGRPSHVFDLDKIHGGIDVRWGKRGESLKLLNGNTIELDETVGVISDGAQVESLAGIMGGDSTAVTLDTTNIYLEAAFWWPDSIRGRARKYNFSTDAAHRFERGVDYSTTVEHVERITQLILDICGGQAGPVDDQIVNLPQRAPVSMRASRANRIIGVEIGEDEIAQIFTRLGLAFERDGDVFRVTPPPHRFDIEIEEDLIEEVARIYGFEKIPARPPVAKSEMRATDETRRSVHAIRHALAARDYAETVNFSFVDAEWERDFAGNDNPVRLLNPIASQLSVMRTTLFGSLVGVLRHNLNRRAERVRVFEAGRVFVADPSVKAGELAVEGYAQPKRIGALAYGPVVEEQWGTATRQVDYFDVKGDLEALLAPVPARFVKAEHPALHPGRSARIEVDGHAVGWIGELHPRLMQKYELPHAPVMFEIDTDALVARALPAPSEVSKFPPVRRDIAVVVDQKVEVQALFDEMKKALADDACKFVQRVALFDEFRAKSNTSGGLSAHEKSLAFRVTLQDAAGTLQDETVDQAIQTLVDRMARVYGARLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDC10_CHICK
Sequence: MRMTMEEMKNEAETTSMVSMPLYAVMYPVFNELERVNLSAAQTLRAAFIKAEKENPGLTQDIIMKILEKKSVDVNFTESLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAIKELLDTVNNVFKKYQYQNRRALEHQKKEFVKYSKSFSDTLKTYFKDGKAINVFISANRLIHQTNLILQTFKTVA
What is the function of this protein?
Promotes cell proliferation.  Modulates apoptotic pathways.  Increases mitogen-activated protein kinase activity.  Important for cell migration, and for normal structure and assembly of the Golgi complex.  Important for KDR/VEGFR2 signaling.  Required for normal cardiovascular development.  Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development.
What are the official names of this protein?
Programmed cell death protein 10.
What is the protein family that this protein belongs to?
Belongs to the PDCD10 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NU4LM_PHAVS
Sequence: MTSINLNLTVAFSLALAGVLIYRSHLMSTLLCLEGMMLSLFIMMALLISHFHMFSTSMMPIILLVFSACEAGVGLALLVKISNNYGNDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: CB068_XENLA
Sequence: MEEEGEAQGRAVPGGRLNMSHGFVHHIRRNQLARDDYDREVKQAKEKQKKRYTPGPTRQKKPDLQVYHPRQREKAHTTETLKDEPNDNGTQLFCLDFEADGGEVTSIIVYEDDDAEQLATMISNQNQLEGDMREALKQRIQEEISKRRVQR
What are the official names of this protein?
UPF0561 protein C2orf68 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0561 family.
Protein: RS2_STRS7
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLTNWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLADAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PVH1_YEAST
Sequence: MAGNANSVDEEVTRILGGIYLGGIRPIIDHRPLGAEFNITHILSVIKFQVIPEYLIRKGYTLKNIPIDDDDVTDVLQYFDETNRFIDQCLFPNEVEYSPRLVDFKKKPQRGAVFAHCQAGLSRSVTFIVAYLMYRYGLSLSMAMHAVKRKKPSVEPNENFMEQLHLFEKMGGDFVDFDNPAYKQWKLKQSIKLDPSGSELVSNSGMFKDSESSQDLDKLTEAEKSKVTAVRCKKCRTKLALSTSFIAHDPPSKESSEGHFIKRAANSHRIIDIQESQANCSHFFIEPLKWMQPELQGKQELEGKFSCPGCSSKVGGYNWKGSRCSCGKWVIPAIHLQTSKVDQFPLQSTALPNMVNFESEKVNR
What is the function of this protein?
May be directly involved in signal transduction and/or cell cycle regulation.  It is necessary for maintaining growth rate or spore germination.  Could show both activity toward tyrosine-protein phosphate as well as with serine-protein phosphate.
What are the official names of this protein?
Tyrosine-protein phosphatase YVH1, PTPase YVH1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: RB33B_CHICK
Sequence: MAAELESSLELSFTGSGTVPGGGLPPARSRIFKIIVIGDSNVGKTCLTYRFCAGRFPQRTEATIGVDFRERAVTIDGERIKIQLWDTAGQERFRKSMVQHYYRNVHAVVFVYDMTNLASFHSLPSWIEECKQHLLTNDIPRILVGNKCDLRNAIQVPTDLAQKFADTHSMPLFETSAKNPNDNDHVEAIFMTLAHKLKSHKPLMLSQPPDRDQIHIKPEPKPAMTCWC
What is the function of this protein?
Protein transport.  Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking (By similarity).  It is involved in autophagy, acting as a modulator of autophagosome formation (By similarity).
What are the official names of this protein?
Ras-related protein Rab-33B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Lipid-anchor. Golgi apparatus, cis-Golgi network. Note=Under starvation conditions punctate RAB33B-positive structures are often observed in the cytoplasm.
Protein: PTH_ALISL
Sequence: MSNQIKLLVGLANPGLEYKRTRHNAGAWVVEELARIHNIPMREEAKFFGLTGRIQTNGQDLRLLIPTTFMNLSGKAIASIAKFYQIKPEEILVAHDELDLPPGVAKFKKGGGHGGHNGLRDTISKLANTKEFYRLRIGIGHPGHKDKVAGFVLGKAPTKEQELIDAAVDESTRCLDILLKDGLSKAQNRLHTFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y925_CROS8
Sequence: MEMTHAQRLILSNQYKMMTLLDPENGERYRRLQTIIERGYGLQMRELDRDFGELSEETCRTVIDIMEMYHALQVSRSNMKEGQSIDERRVTFLGFDAATEARFLGYVRFLVNTEGRYTHFDAGTHGFNAQTPMWEKYQRMLKVWQACPRQYHLCANEIMQIINA
What are the official names of this protein?
UPF0304 protein ESA_00925.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: RS19_STRT1
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: 101L_IIV6
Sequence: MELYCKLIMVTQNNNNKYYEMKYEGGDTFTVIYGRVDQSSTVISKPFKEWDKIKNSKLKKGYKDVSSKSVSSVESNEREIENKSIKEFIHKMRAYTNLLVSNTYSVNSKEVSSSQISNAQKLLNKISSMDMDENVDEINELLILLYTCIPRKIKNVKKCILPYIDIKQTIIQEQDNLDALSSQLKKNVSQNNKINNILNVHFSKFLEEASSSFNIDVCKLKSILNEDKTFLEMI
What are the official names of this protein?
Uncharacterized protein 101L.
Protein: VE1_HPV11
Sequence: MADDSGTENEGSGCTGWFMVEAIVEHTTGTQISEDEEEEVEDSGYDMVDFIDDRHITQNSVEAQALFNRQEADAHYATVQDLKRKYLGSPYVSPISNVANAVESEISPRLDAIKLTTQPKKVKRRLFETRELTDSGYGYSEVEAATQVEKHGDPENGGDGQERDTGRDIEGEGVEHREAEAVDDSTREHADTSGILELLKCKDIRSTLHGKFKDCFGLSFVDLIRPFKSDRTTCADWVVAGFGIHHSIADAFQKLIEPLSLYAHIQWLTNAWGMVLLVLIRFKVNKSRCTVARTLGTLLNIPENHMLIEPPKIQSGVRALYWFRTGISNASTVIGEAPEWITRQTVIEHSLADSQFKLTEMVQWAYDNDICEESEIAFEYAQRGDFDSNARAFLNSNMQAKYVKDCAIMCRHYKHAEMKKMSIKQWIKYRGTKVDSVGNWKPIVQFLRHQNIEFIPFLSKLKLWLHGTPKKNCIAIVGPPDTGKSCFCMSLIKFLGGTVISYVNSCSHFWLQPLTDAKVALLDDATQPCWTYMDTYMRNLLDGNPMSIDRKHRALTLIKCPPLLVTSNIDISKEEKYKYLHSRVTTFTFPNPFPFDRNGNAVYELSDANWKCFFERLSSSLDIEDSEDEEDGSNSQAFRCVPGSVVRTL
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.