PharMolix/UniProtQA huggingface dataset:
Protein: PUR5_SYNPW
Sequence: MDYRSAGVDVEAGRAFVDRIRTSVEATHRPEVVGGLGGFGGLMRLPEGLRKPLLVSGTDGVGTKLELAQDHKSHHNVGIDLVAMCVNDVITSGAEPLFFLDYMATGALSPDAMAEVVEGIADGCRQSGCALLGGETAEMPGFYPPGRYDLAGFCVAVVEEDNLIDGRRVQAGDSILGIASSGVHSNGFSLVRKILECCAAGADTRVGPEQTPVIEALLKPTHLYGALVRTLLGANTRIHAMAHITGGGIPENLPRCLPKGLMASVDPHSWPRPELFSWLQTQGELQERDLWHTFNLGIGYCLILPEADVEGARTLCSNSGFESWVIGEVIPASEPQDGPVAGLPA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSH_ADE07
Sequence: MATPSMMPQWAYMHIAGQDASEYLSPGLVQLARATDTYFSMGNKFRNPTVAPTHDVTTDRRQRLMLRFVPVDREDHTYSYKVRYTLAVGDNRVLDMASTFFDIRGVLDRGPSFKPYSGTAYNSLAPKGAPNTSQWIVTAGEERAVTTTTNTFGIASMKGDNITKEGLEIGKDITADNKPIYADKTYQPEPQVGEESWTDTDGTNEKFGGRALKPATKMKPCYGSFARPTNIKGGQAKNRKVKPTEGDVETEEPDIDMEFFDGREARDAFSPEIVLYTENVNLETPDSHVVYKPGTSDDNSHANLGQQAMPNRPNYIGFRDNFVGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSLGDRTRYFSMWNQAVDSYDPDVRIIENHGIEDELPNYCFPLDGIGPAKTYQGIKSKDNGWEKDDNVSKSNEIAIGNNQAMEINIQANLWRSFLYSNVALYLPDVYKYTPTNITLPANTNTYEYMNGRVVSPSLVDSYINIGARWSLDPMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAVKNLLLLPGSYTYEWNFRKDVNMVLQSSLGNDLRTDGASISFTSINLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPANATNIPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSGSIPYLDGTFYLNHTFKKVSIMFDSSVSWPGNDRLLSPNEFEIKRTVDGEGYNVAQCNMTKDWFLVQMLANYNIGYQGFYIPEGYKDRMYSFFRNFQPMSRQVVDEVNYTDYKAVTLPYQHNNSGFVGYLAPTMRQGEPYPANYPYPLIGTTAVKSVTQKKFLCDRTMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTFEVDPMDEPTLLYLLFEVFDVVRVHQPHRGVIEAVYLRTPFSAGNATT
What is the function of this protein?
Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid.  Assembled into trimeric units with the help of the chaperone shutoff protein.  Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid.  Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.
What are the official names of this protein?
Hexon protein, CP-H, Protein II.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Forms the capsid icosahedric shell. Present in 720 copies per virion, assembled in 240 trimers.
Protein: RL24_SALSV
Sequence: MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKKHQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSETIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MRAY_RHOP5
Sequence: MLYWLVDFASSVPALNVFRYITFRTGGAMVTGALFVFMFGPWIIDNLRLRQGKGQPIRSDGPQSHLSKKGTPTMGGLMILSGLVVGTVLWANPLNPYVWIVLAVTLGFGFVGFYDDYLKVTKQSDKGFSGRTRLAIETIIAAAACYALMRLGRDPLSSSLAVPFLKDTAIYLGWFFVIFGGFIVVGAGNAVNLTDGLDGLAIVPVMIAAASFGLVSYLAGNAVFADYLQINYVAGTGELAVLCGALLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGTIAVAVKHEFVLAVIGGLFVLEAVSVIVQVASFKLTGKRVFRMAPIHHHFEQKGWTEPQIVIRFWIISVMLALAGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GREA_VEREI
Sequence: MTTIPITKRGAEKLKQELHHLKTVERPSVITAIAEARAQGDLSENADYDAAKDRQGFVEGRIQEIEGKLSVAQVIDPGEVDGGGKVVFGATVQLEDEESGDTVTYQIVGEDEADLKQGLINISSPIARALIGKEEGDTAEVQAPSGIRRYEVVAVSYR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: LRC4B_RAT
Sequence: MAQAHIQGSPCPLLPPGRMSWPQGALLLLWLFSPPLRAGGGGVAVTSAAGGGSPPATSCPAACSCSNQASRVICTRRELAEVPASIPVNTRYLNLQENSIQVIRTDTFKHLRHLEILQLSKNLVRKIEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELKRLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVATIERNAFDDLKSLEELNLSHNNLMSLPHDLFTPLHRLERVHLNHNPWHCNCDVLWLSWWLKETVPSNTTCCARCHAPAGLKGRYIGELDQSHFTCYAPVIVEPPTDLNVTEGMAAELKCRTGTSMTSVNWLTPNGTLMTHGSYRVRISVLHDGTLNFTNVTVQDTGQYTCMVTNSAGNTTASATLNVSAVDPVAAGGPGGGGPGGGGGAGGAGGYTYFTTVTVETLETQPGEEAQQPRGTEKEPPGPTTDGAWGGGRPDAAAPASASTTAPAPRSSRPTEKAFTVPITDVTENALKDLDDVMKTTKIIIGCFVAITFMAAVMLVAFYKLRKQHQLHKHHGPTRTVEIINVEDELPAASAVSVAAAAAVAGGAGVGGDSHLALPALERDHLNHHHYVAAAFKAHYGGNPGGGCGAKGPGLNSIHEPLLFKSGSKENVQETQI
What is the function of this protein?
Synaptic adhesion protein.  Regulates the formation of excitatory synapses.  The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner.
What are the official names of this protein?
Leucine-rich repeat-containing protein 4B, Netrin-G3 ligand, NGL-3.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Presynaptic cell membrane.
Protein: RS16_XANC5
Sequence: MVKIRLTRGGAKKRPFYHIIVTDVRSARDGRNIERLGYYNPVAQGAEPRIVLDVARVDHWVGNGAQLTDKVRNLYREAKSQAAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MURG_SULNB
Sequence: MSIIMTGGGTGGHLAIIKAVKEQLKGEELIYIGSTTGQDRQWFENDEDFTETYFFDTRGVVNQRGFGKLKSLWMMLQAMMKARKLLKKYDAKVVFSVGGFSSAATAFAAKSASVPLVIHEQNAALGSLNKLLRPYAAAFISSYLEESPIKAYPIKEVFFDNVRVRKNVETIIFLGGSQGAKAINKLALEIAPKLKERGIRIIHQAGEKNIDEVRKDYEDIGIEAEVFGFTTKLADYMKEADLAIARAGASTLWELSATALPTLFIPYPYAVSDHQYYNAQFLVEKDLAWIMREGEIDTQKVLALLGEDLETKSRGLMEIVEKDGSKQIADLLKNYAKS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TOM22_CAEEL
Sequence: MALVRDDFDDIPDSEIHETIVERIEGLGEMFPDALRSAVHSTVDWSIWGVKGVFSLTKSTIWVVSTTSLIAFLPYIIEKERSDLEKTQVAQQRQMLLGPSAAIQQAKTA
What is the function of this protein?
Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins (By similarity).  Together with the peripheral receptor tomm-20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (PubMed:21264209).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM22 homolog.
What is the protein family that this protein belongs to?
Belongs to the Tom22 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: AROD_STRT2
Sequence: MKIVVPIMPTSLEEAQALELSRFEGADIIEWRADFLDKHSILTVAPAIFEKFAGFEIVFTIRTTREGGKIELTDGEYVTLIKDVAAIYSPDYIDFEYFTRKEVFDQMLGFSNLVLSYHNFEETPENLMELLSEMTNLTPRVVKVAVMPKNEQDVLDLMNFTRGFKAFNPEQEFVTMSMGKLGRLSRLAGDLVGSSWTFASLDNTSAPGQVALADMCRIREVLDAD
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: DHE3_PYRAB
Sequence: MVEQDPFEIAVKQLERAAQYMKISEEALEFLKRPQRIVEVTIPVEMDDGSVKVFTGFRVQYNWARGPTKGGIRWHPEETLSTVKALAAWMTWKTAVMDLPYGGGKGGIIVDPKKLSDREKERLARGYIRAIYDVISPYEDIPAPDVYTNPQIMAWMMDEYETIARRKTPAFGIITGKPLSIGGSLGRNEATARGASYTIREAAKVLGWDDLKGKTIAIQGYGNAGYYLAKIMSEDYGMKVVAVSDSKGGIYNPDGLNADEVLKWKREHGSVKDFPGATNITNEELLELEVDVLAPAAIEEVITKKNADNIKAKIVAEVANGPVTPEADEILFEKGILQIPDFLCNAGGVTVSYFEWVQNITGYYWTLEEVREKLDKKMTKAFYDVYNTAKEKNIHMRDAAYVVAVQRVYQAMLDRGWVKH
What are the official names of this protein?
Glutamate dehydrogenase, GDH.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM41_KOMPG
Sequence: MFTLAARRLAIRLPRVRFGSSSAYDEALATIRNDLKLNFRFKADVLEKNVIRSILAETKNLEIDNKDKDLDEFKLYDLLSKMIKQRQDSAAIYLKEGSPDRFRQTGWNELREVDYITKYLEALPVASAEEIEAKVEPIVQSVLEEEGELKSPKEIFSRIPWKVVNQDWQASEGAVKNTVLRLYNLYKTDA
What are the official names of this protein?
Altered inheritance of mitochondria protein 41, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM41 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYC_STRT2
Sequence: MIKIYDTMTRSLRDFVPLTENTVNMYVCGPTVYNYIHIGNARSTVAFDTIRRYFEYRGYTVNYISNFTDVDDKIIKAANEVGISTKELSDKFITAFMEDTAQLGIKPATQNPRVINYMDEIIAFVSILIDKGFAYVSEGDVYFRVTKSNNYAKLANKTLEDLEIGASGRTDAETDRKEDPLDFALWKAAKEGEISWESPWGPGRPGWHIECSVMATEILGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVNVDNEKMSKSLGNFVTVHDMLKTVDGQVLRFFLATQQYRKPINFTEKAIHDAEVNLKYLKNTHSLPLTEEVSQAELQAYLDAFQAAMDDDFNTANGVTVLFDMAKWINSGNYDETVKDAFEKILQVFGIVFEEETLDEDIEKLIEERQAARANKDFATADRIRDELAAQGIKLLDTKEGVRWTRD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRS6A_HUMAN
Sequence: MNLLPNIESPVTRQEKMATVWDEAEQDGIGEEVLKMSTEEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYYA
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 6A, 26S proteasome AAA-ATPase subunit RPT5, Proteasome 26S subunit ATPase 3, Proteasome subunit P50, Tat-binding protein 1, TBP-1.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Colocalizes with TRIM5 in the cytoplasmic bodies.
Protein: PSBH_AGRST
Sequence: MATQTVEDSSKPRPKRTGAGSLLKPLNSEYGKVAPGWGTTPFMGVAMALFAIFLSIILEIYNSSVLLDGILTN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS16_PASMU
Sequence: MVTIRLSRGGAKKRPFYQIVVADSRSPRDGRFIERVGFFNPLATGNAERLRLDLDRVNAWVEKGASLSDRVSALVKEAQKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MAO1_ALIFM
Sequence: MNNNKRPLYIPYAGPALLSTPLLNKGSAFSTTERKYFNLEGLLPEAIESIEEQTGRAYKQYQSFENDMDKHIYLRNIQDTNETLFYRLVQNHISEMMPIIYTPTVGAACENFSNIYRRGRGLFISYENKNRIDDLLNNAANQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLALYTACGGISPAHTLPIVLDVGTNNPQRLADPMYMGWRHPRVTGDEYADFVEDFIQAVQRRWPEALVQFEDFAQKNAMPLLERYKNRICCFNDDIQGTAAVTVGSLLAACKAAGSSLSEQRVTFLGAGSAGCGIAEAIIAQMVSEGISDAQARSQVYMVDRWGLLQEGMPNLLDFQQRLVQKAENTKDWISEEPNFSLVDVMRNAKPTVLIGVSGAPGLFSKEVIQEMHKHCERPIVFPLSNPTSRVEATPNDIIRWTNGQALVATGSPFDPVSHNGQTYPIAQCNNSFIFPGIGLGVLAIKATRVTDEMLMESSRALAECSPLAINGTGALLPPLEEIHSVSKRIAFAVAKKAIEQGHALEITDEALHQKIESYFWKPVYRRYKRTAF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: NUOB_BACFR
Sequence: MEIMKKPKIKSIPYEDFIDNESLEKMVKELNEGGANVFVGVLDDLINWGRSNSLWPLTFATSCCGIEFMALGAARYDMARFGFEVARASPRQADMIMVCGTITNKMAPVLKRLYDQMADPKYVIAVGGCAVSGGPFRKSYHVVNGVDKILPVDVYIPGCPPRPEAFYYGMMQLQRKVKIEKFFGGVNRKEKKPEGK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OPLA_RAT
Sequence: MGSPEGRFHFAIDRGGTFTDVFAQCPGGHVRVLKLLSEDPANYADAPTEGIRRILEQEEGVLLPRGRPLDTSRIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVLEVDERVVLYRGEPGAGSPVKGRTGDLLEIQQPVDLEALRGKLEGLLSRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSATTYHLEGGQPVIGFDMGGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLTNGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLEEQCVDALQVQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATACSPRAGDFGAAFVERYMREFGFIIPERPVVVDDVRVRGTGRSGLQLEDTPKIQTGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVTDTGDIRISVGAEGPSMADTRLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALRAPGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAEDHMDDGSPICLRVQINLSQGSAVFDFTGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVRVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACSASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGARGLNLLIRKDGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDPAPPPGSPPLFPAFPERGSVFEYRRAQEAV
What is the function of this protein?
Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase, 5-oxo-L-prolinase, 5-OPase, Pyroglutamase.
What is the protein family that this protein belongs to?
Belongs to the oxoprolinase family.
Protein: PG039_VACCW
Sequence: MDLSRINTWKSKQLKSFLSSKDAFKADVHGHSALYYAIADNNVRLVCTLLNAGALKNLLENEFPLHQAATLEDTKIVKILLFSGLDDSQFDDKGNTALYYAVDSGNMQTVKLFVKKNWRLMFYGKTGWKTSFYHAVMLNDVSIVSYFLSEIPSTFDLAILLSCIHITIKNGHVDMMILLLDYMTSTNTNNSLLFIPDIKLAIDNKDIEMLQALFKYDINIYSANLENVLLDDAEIAKMIIEKHVEYKSDSYTKDLDIVKNNKLDEIISKNKELRLMYVNCVKKN
What is the function of this protein?
Inhibits antiviral activity induced by type I interferons.  Does not block signal transduction of IFN, but is important to counter the host antiviral state induced by a pre-treatment with IFN.  Plays a role in the inhibition of host NF-kappa-B activation by preventing the acetylation of the RELA/p65 subunit of NF-kappaB.
What are the official names of this protein?
Interferon antagonist OPG040, 32.5 kDa protein, Host range protein 1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG039 family.
Protein: PHXR5_MOUSE
Sequence: MNKDHGCGHICKEAPRGSVACECRPGFELAKNQKDCICKYELSISEVGTAYTEVRKTTTGTATGIATGTCTGTGRVKATGRGTGTDTDTGTVTARATVTARVTGTGTGTATVTETGTAKVTDTGTGTGTAKVTGTAKVTGTGTGTGTGTGTGTGTGTGTGTGTAKVTGTGTDRGTGTGTGTGTGTGTGTGTGTAKVTGTAKVTGTGTGTAKVTGTGTGTGTGTGTGTGTGTDTGTGTAKVTGTGTGTGTGTGTGTGTGTGTGTGTAKVTGTGTDRGTGTGTGTGTGTGTGTGTGTGTAKVTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGSGSGTGTGTGTGSGSGTGTGTGSGSGTAKVTGTATGTGTGTDTGTGTGTGTGTGTGSGSGTAKVTGTATTTATVTETGTAKVTGTDTGTAKVTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGSGSGTAKVTGTDTGTAKVTGTGTGTGTGTGTGTGTGTGTGTGTGSGSGSGSGSGSGSGTGTGTGLGSGSGSGTAKVTGTGTAKVTGTGTGTGTGTGSGSGSGSGSGSGSGSGSGSGSGTGTGTGLGSGSGSGSGTGTGTGTGTGTGTGTGTGTSTVTVRGTGTGTATATGTGTGTGTGTGTGTGTGTGTDTSTGTDRGTGTGTGTA
What are the official names of this protein?
Putative per-hexamer repeat protein 5.
Protein: PDXK_ECOK1
Sequence: MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNIFELEILTGKDCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNVISHSRVKTDLKGTGDLFCAQLISGLLKGKALTDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: DHTK1_XENLA
Sequence: MNVFAHRCSSCRRAVVLWRPGLHRLYRTERGVYGYRPKISAGSQLQESSTRGKQAASPTVDHGLARLVTAYREHGHKAAKINPLFTGQAVMDMVPEIQEIMEILHGPFSTTGLLNMGKSEATIEEVLAYLDHTYCGQISIETSQLQNYKEREWFSRRFEELKQESFSTEERKHLARLMLECQEFDHFLATKFSTVKRYGGEGAESMMGFFHEMLKMCSFGGVTDVIIGMPHRGRLNLLTGLLQFPPELMFRKMRGLSEFPENSPSIGDVLSHLTSSVDLDFGSHRPLHVTMLPNPSHLEAINPVAVGKTRARQQSLSDGDYSTESSAQPGDKVVCLQVHGDASISGQGIVTETFTLSNLPHYRIGGSIHLIVNNQLGYTTPAERGRSSLYSSDVGKIVGCAVIHVNGDDPEEVLRATRLAVEYQRCFRKDVIIDLLCYRQWGHNELDEPFFTNPSMYKIIRSRKSIPDVYSERLIAEGLMTEEEATEIRTTYYSKFNDHLSNMTLYSPPSTNLQAHWREMIEPSARTTTWDTGLPADLLKFIGAKSVEVPEEFKMHSHLLKMHAQSRVQKLQEATKLDWATAEALAFGSLLCQGFNIRISGQDVGRGTFSQRHAMLVCQETNDTYIPLNHMTPDQKGFLEVSNSALSEEAVLGFEYGMSIESPKLLPIWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPEHSSCRIERFLQMCDSTEEGVDGDTVNMFVVHPTTPAQYFHLLRRQMVRSFRKPLIVASPKMLLRYPAAVSSLEDIAPGKTFRSVIGDSSADPKSVSKVILCSGKHYYALHKQREALGEQGRSSAIIRVEELCPFPLEALQQEIHRYPKAKDFIWSQEEPQNMGAWTFVAPRFEKQLACKLRLVSRPALPAPAVGIGTLHQQQQEEITVKTLS
What is the function of this protein?
2-oxoadipate dehydrogenase (E1a) component of the 2-oxoadipate dehydrogenase complex (OADHC).  Participates in the first step, rate limiting for the overall conversion of 2-oxoadipate (alpha-ketoadipate) to glutaryl-CoA and CO(2) catalyzed by the whole OADHC.  Catalyzes the irreversible decarboxylation of 2-oxoadipate via the thiamine diphosphate (ThDP) cofactor and subsequent transfer of the decarboxylated acyl intermediate on an oxidized dihydrolipoyl group that is covalently amidated to the E2 enzyme (dihydrolipoyllysine-residue succinyltransferase or DLST).  Can catalyze the decarboxylation of 2-oxoglutarate in vitro, but at a much lower rate than 2-oxoadipate.  Responsible for the last step of L-lysine, L-hydroxylysine and L-tryptophan catabolism with the common product being 2-oxoadipate.
What are the official names of this protein?
2-oxoadipate dehydrogenase complex component E1, E1a, OADC-E1, OADH-E1, 2-oxoadipate dehydrogenase, mitochondrial, Alpha-ketoadipate dehydrogenase, Alpha-KADH-E1, Dehydrogenase E1 and transketolase domain-containing protein 1, Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ICK9_TRILK
Sequence: MMKLYSLVIIATLAAAAFAATSEEISAAVSEIISQHQQDLERYAKIVERGEEPKKYIRCSKQLGEKCDLNCECCGAAAYCEDIVYICKEKISDNSILNAFGQAMTAMGNAVSRYYCDAE
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Toxin ICK-9.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. ICK-8 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IPT1_YEAST
Sequence: MNVIFSLASFVKNMYNASLNQRNLISLPFNFMLNFAPVFIWLSIFKRAGLIPIRLRPDIHSKFAFFADQFLFGDYWHELTVQLPDNTSKLFFWSFISSSAFLLVFLICIPFAIWYYIYYIKHVNYNLLEWFANIFHYPCKRKQRPIQKRFRTIFIPFALPLFTFVILNIDHFFAYQSDANFTKTKDLLAWFSYVILHLTAPILTAVYLYVFQPPGTLKCFSFALGLQNIAGVLTHLLVPMASPWFTHLYGIDDTEHVNYTQEGFAAGLIRVDSHLGTHLNTKGFHMSPIVFGAVPSLHSAIAFQCFLFLVSRSTSLKHRFSNAGGFTMHNNDSSTFKLSEEDSEDEGDNSIPPTIGPNDLEMEPLGTVEPVDISNERSSSPSSSFTVSSNERSTGGGDGSIINSNGNKKPLQFVHLYDEDTNFTNKWIFKIVNDGFIPKFWAILYIILQWWATMYLDHHYRFDLFVGVLYAMTSFIIINWFVLQPKVLKKWIHIRLGDKVDTRNEARTFGMRVFCGTKMEWFFDPLA
What is the function of this protein?
Catalyzes the addition of a phosphorylinositol group onto mannosyl phosphorylinositol ceramide (MIPC) to form mannosyl diphosphorylinositol ceramide (M(IP)2C), the major sphingolipid in membranes of S. cerevisiae.
What are the official names of this protein?
Inositolphosphotransferase 1, Mannosyl diphosphorylinositol ceramide synthase.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: DCD_PSYWF
Sequence: MSIKSDRWIRKMAEEHGMIEPYEPGQVRFNEAGDKLVSYGTSSYGYDVRCAREFKVFTNVHSAIVDPKNFDENSFIDIVGDECIIPPNSFALARTVEYFRIPRDVLTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTTLPARIYAGEGVAQMLFFQSDADDICETSYKDRGGKYQGQRGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.