PharMolix/UniProtQA huggingface dataset:
Protein: HFLD_ENT38
Sequence: MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSVIDLNPGSTLGVFGGSETNLRLGLETLLGVLNASNRQGLNAELTRYTLSLMVLERKLNSAKGAMDTLGDRIAGLQRQLDHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQSSQVQAKVRASLLAGIRAAVLWHQVGGGRLQLMFSRNRLTAQAKQILAHC
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RRF_PSEPK
Sequence: MINDIKKDAQERMGKSIEALSRNLAAIRTGRAHPSILDSVKVTAWGSEMPLNQVAAITVEDARTLKIVAHDKNLSAAIEKAILTSDLGLNPSSAGTTIRVPMPALTEETRKGYTKQASGVAEDAKVAVRNVRRDALADLKKLTKDKEISEDEERRAADEIQKLTDKFVAEVDAAFKAKEKDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUN1_MOUSE
Sequence: MDFSRLHTYTPPQCVPENTGYTYALSSSYSSDALDFETEHKLEPVFDSPRMSRRSLRLVTTASYSSGDSQAIDSHISTSRATPAKGRETRTVKQRRSASKPAFSINHLSGKGLSSSTSHDSSCSLRSATVLRHPVLDESLIREQTKVDHFWGLDDDGDLKGGNKAATQGNGELAAEVASSNGYTCRDCRMLSARTDALTAHSAIHGTTSRVYSRDRTLKPRGVSFYLDRTLWLAKSTSSSFASFIVQLFQVVLMKLNFETYKLKGYESRAYESQSYETKSHESEAHLGHCGRMTAGELSRVDGESLCDDCKGKKHLEIHTATHSQLPQPHRVAGAMGRLCIYTGDLLVQALRRTRAAGWSVAEAVWSVLWLAVSAPGKAASGTFWWLGSGWYQFVTLISWLNVFLLTRCLRNICKVFVLLLPLLLLLGAGVSLWGQGNFFSLLPVLNWTAMQPTQRVDDSKGMHRPGPLPPSPPPKVDHKASQWPQESDMGQKVASLSAQCHNHDERLAELTVLLQKLQIRVDQVDDGREGLSLWVKNVVGQHLQEMGTIEPPDAKTDFMTFHHDHEVRLSNLEDVLRKLTEKSEAIQKELEETKLKAGSRDEEQPLLDRVQHLELELNLLKSQLSDWQHLKTSCEQAGARIQETVQLMFSEDQQGGSLEWLLEKLSSRFVSKDELQVLLHDLELKLLQNITHHITVTGQAPTSEAIVSAVNQAGISGITEAQAHIIVNNALKLYSQDKTGMVDFALESGGGSILSTRCSETYETKTALLSLFGVPLWYFSQSPRVVIQPDIYPGNCWAFKGSQGYLVVRLSMKIYPTTFTMEHIPKTLSPTGNISSAPKDFAVYGLETEYQEEGQPLGRFTYDQEGDSLQMFHTLERPDQAFQIVELRVLSNWGHPEYTCLYRFRVHGEPIQ
What is the function of this protein?
Isoform 5 may be involved in nuclear remodeling during sperm head formation in spermatogenesis.  A probable SUN1 isoform 5:SYNE3 LINC complex may tether spermatid nuclei to anterior cytoskeletal structures such as actin filaments present at membraneous junctions of spermatids and Sertoli cells.
What are the official names of this protein?
SUN domain-containing protein 1, Protein unc-84 homolog A, Sad1/unc-84 protein-like 1.
What are the subcellular locations of this protein?
Nucleus inner membrane; Single-pass type II membrane protein. Note=At oocyte MI stage localized around the spindle, at MII stage localized to the spindle poles. In round spermatids mainly localizes to the posterior pole of the nucleus. This localization is gradually disappearing during spermiogenesis. In elongated spermatids localizes to anterior regions outside the nucleus indicative for isoform 5. SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane. Note=Localized to the anterior pole of spermatids.
Protein: RL24_CLONN
Sequence: MAKVHVRRTDKVVVISGKDKGKVSEVLAVYPKTSKVLVKDANVVTKHVKPNRENMQGGIVKKEAPMNSSKVMLYCTNCNSATRISKKLLEDGTKVRVCKKCGEIL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: PSAI_TOBAC
Sequence: MTNLNLPSIFVPLVGLVFPAIAMASLFLHVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MSRAB_NEIMB
Sequence: MKHRTFFSLCAKFGCLLALGACSPKIVDAGAATVPHTLSTLKTADNRPASVYLKKDKPTLIKFWASWCPLCLSELGQTEKWAQDAKFSSANLITVASPGFLHEKKDGDFQKWYAGLNYPKLPVVTDNGGTIAQSLNISVYPSWALIGKDSDVQRIVKGSINEAQALALIRDPNADLGSLKHSFYKPDTQKKDSKIMNTRTIYLAGGCFWGLEAYFQRIDGVVDAVSGYANGNTKNPSYEDVSYRHTGHAETVKVTYDADKLSLDDILQYFFRVVDPTSLNKQGNDTGTQYRSGVYYTDPAEKAVIAAALKREQQKYQLPLVVENEPLKNFYDAEEYHQDYLIKNPNGYCHIDIRKADEPLPGKTKTAPQGKGFDAATYKKPSDAELKRTLTEEQYQVTQNSATEYAFSHEYDHLFKPGIYVDVVSGEPLFSSADKYDSGCGWPSFTRPIDAKSVTEHDDFSYNMRRTEVRSHAADSHLGHVFPDGPRDKGGLRYCINGASLKFIPLEQMDAAGYGALKGKVK
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: RL24_MARMM
Sequence: MAAKIKKGDKVVILAGRDKGKTGEVTKVLPTEDRVVVAGVNVVKRHTRATQTEQGGIIEKEASIHVSNVAVADPKTGEATRVGFKTEDGKKVRVAKSSGEVIDV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: COLL8_MIMIV
Sequence: MSSYNSPHAYYPHDNTIINISGSDNTTNINTTTINSTSVDQDIHYYEDGTHYDRRNTHANCNNYNVGNGIGRNIIDNNRHESIRDCNESIRNVLQGRLNRSDNSCRLDVNSQILVGVGAPANSCGTNGDIYIDKCTRDYYTNRNRIWVFVGNLECREQIYGTGGCKGEKGIKGELGPKGNTGQKGDIGSKGDRGDKGEPTISMFSYINSYEQSVPGGFTSVVPSKATIAYISCVGGGGGGSSGSGNSGFHGGGAGGSVIKYPVSVVENQVIRGTVGAGGSGGQVGTLGMCGTDTVVTIGTLTITAKAGLSPTETSGGDGGTVIFAQGMFSPAIAKGGTLSSPSGSNGNVGFFAFSGAGGGFRGGNGGNILAFNGGKSQGPDTAGGGGASAFADGGSITIRGCVTASKGSGGGGAIQTGPVSISGVAGNGGNGYVRIDYYSQ
What are the official names of this protein?
Putative collagenous domain-containing protein R238.
Protein: THIM_CHLAD
Sequence: MTFNDRIAELRDRVRQQRPLIHHITNFVVMNDTANVTLHIGGLPVMAHDREEVAEMVAAAGALVLNVGTLSPDWIEAMIIAGKRANELGIPIVLDPVGAGATSLRTSSNRRLLETLQVAVIRGNSGEIGALAGMGGVVKGVEAVVEADDPLAAAQVLARQYHTVVAVTGRRDLVTDGSRVLAVDNGHEWLKTLTGTGCSATTVIAAFTAVERDYLFAAAAGLACFGLAAELAAPQARGPASFKVAFYDAIYHLAADQIRAGARVVDLSTEQSKAVAQS
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: ATP6_BORPE
Sequence: MAAPSGASPQSEYIQHHLVHLNNIGEKQSVIAQFNVINYDSLFWSILMGLLVVFCLWLAARRATAGVPGRFQGFIEMIVDMVDDQAKSIVTNAKSRLFVAPLALTVFLWIILMNALDLLPVDLLPSIWRMTGLGAEHGDPLYYHRILPTADLNVPMGMSLGVLLLMFYYGIKIKHPGGFVKELFTAPFHAHGLASLVLAPFNLLLNLIEYAAKSVSLGMRLFGNMFAGELIFMLIALLGGAWTGFNGASIGLGIGHVLAGSVWAIFHILIVLLQAFIFMMLTLVYIGQAHEGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ZAPD_BURA4
Sequence: MILYEYPFNERIRTLLRLEDLFERFAFFLAQEDPREHHVALTTLFEIAEVTGRADLKSDLMKELERQRQTLAPFRGNPGIEQNALEAVLGEIEQTLANLAQMQGKTGQHLVDNEWLASIRSRAVIPGGTCKFDLPSYYAWQQWPAEQRRQDIAKWIMPLLPLRDAAAIVLRLARESGQASKVMAMQGSYQQMLSGRSYQLMQVRVPPELRVIPEASANKYMLWVRFTMQDGDVRPRAVDIDVPFHLTLCNL
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: SECB_ACTPJ
Sequence: MTEENQVTAQEEAQTPFELQIQRIYIKDVSFEAPNLPTIFHQEWKPQLGFELDTETKQLDEDLYEVVLHINVSTTLEDSGDTAFICEVKQAGVFTIKGIEGIQLAHCLASQCPNVLYPYARELISSLVNRGTFPALNLSPVNFDALFMDYLQRQEAEQNAEAPAVN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMS_PYRAB
Sequence: MCGIIGYIGPRKASPIIVEGLKRLEYRGYDSAGIATSHEGRILIKKGAGKIDELAKRLNFTDLPGNIGIGHTRWATHGIPNDTNAHPHTDCTGKIVVVHNGIIENFQELKEELLRQGHVFRSDTDTEVIAHLIEENLRITGNFEDAFRLSLLRLRGSFALVVMFADDPERLYIARKDSPLIIGIGNGEMFIASDIPAFLPYTRKAVFLDDGEYGVVSRNGFTVKDIITGKEKRKKVYEIQWTLEMAEKGGYDHFMLKEIFEQPRAVKDAIYGNLEEVPKIAGLLSKYDRIIITGMGTSYHAALVGKYLIQRFGKIPVLVEEASELRYEYEDILDNKTLLIAITQSGETADTVAAMKLAKSKGSKVIGIVNVVGSLATRIADATLYTHAGPEIGVAATKTYTTQLTVLLLLSLELGKMNGVDTTQVENTLPKLPELIDAGLKMNEKIKELAKSLNDRRDFFYIGRGISYPTALEGALKIKEIAYVHAEGLSAGELKHGPLALIEEGVPVIGVAPSGKTFEKMLSNIEEAKARGGFIITVGDDLRLHQVSNVFIRLPKVPEEVSPITYIVPLQLLAYHLAVLKGHNPDRPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLSA_BACSU
Sequence: MSISSILLSLFFILNILLAIIVIFKERRDASASWAWLLVLFFIPVLGFILYLLFGHNLRRKHLFQWEDRKKIGIERLLKHQLEDLETKQFQFNNRATFDNKDLIYMLIMNNHAVFTEDNSVDVITDGRDKFQRLLSDISKAKDHIHLQYYIYKGDELGKKLRDALIQKAKEGVQVRVLYDELGSRTLRKKFFKELREAGGHVEVFFPSKLRPINLRLNYRNHRKLVIIDGMTGYVGGFNVGDEYLGLNPKFGYWRDTHIRLQGTAVHAIQTRFILDWNQASHHHTLTYIPNHFPDYGPKGNVGMQIVTSGPDSEWEQIKNGYIKMISNAKRSILIQTPYFIPDASLLDALRIACLSGIDVNIMIPNKPDHAFVYWATLSYIGDLLKAGATVYIYDNGFIHAKTIVVDDEIASVGTANIDVRSFRLNFEVNAFIYDITIAKKLVSTFKEDLLVSRKFTYEEYLQRPLWIRIKESVSRLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Major cardiolipin synthase ClsA, CL synthase 2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Localized in the septal membrane. Localization depnds on FtsZ.
Protein: CLPP_MESVI
Sequence: MPIGIPKVAYRIPGEAVSTYVDVYNRLYRERILFLGEDLDDEVANQLIGVMVFLNSEDDTKGIFFYINSPGGSMNAGLGVYDMIQHVNVDVTTICMGLAASMASFILAGGTPGQRLMFPHARVMLHQPMGGNGGKAKYMVEESVEVKRLRELIAHLYVKRTGQSLEKIRKDMNRDNFMRPRQAKEYGLIDHMVTNVNELDELDKQSNDLKKLGKVNLTNIETSNKSELK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: ATPB_MARN8
Sequence: MSSGHIVQIIGAVIDVEFPRDSVPSVYDALLLEGGETTLEVQQQLGDGIVRTIAMGSTEGLKRGLKAENTGKPISVPVGTQTLGRIMDVLGRPIDEQGDIGEEERWAIHRKAPGYADQAASADLLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKEHSGLSVFAGVGERTREGNDFYYEMKESNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGQLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFSHLDATVVLSRDIASKGIYPAIDPLDSTSRQLDPLVIGEQHYNVARGVQNVLQRYKELKDIIAILGMDELSEDDKLIVSRARKIERFLSQPFHVAEVFTGSPGKYVSLKETIASFEGILNGDYDDMPEQAFYMCGGIEEAIEKAKAMKEKEGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSD_GEOSM
Sequence: MRNTDTPIAVEGYPFIAGFAAATLLLALLGQFLHLGFFVPATLFFVLTVFTVFFFRNPERVTPGDENTVVAPADGEVIFLGKVIEPHTNGEFEKISIFMSVFNVHVNRAPISGKVVDGFYTKGKFFDVRDERASFENEQQGLVLETAAGLRMVVVQVAGLIARRIVCYAKTGDSLSRGRRYGLIRFGSRLDIYLPLGTRIDLVMGQKTVAGETVLGILP
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GLMM_METNO
Sequence: MRKYFGTDGIRGRANGVITPELALKVGQAAGLLFQRGEYRHRVVIGKDTRLSGYMIETALVAGFTSVGMDVLLLGPMPTPAVAMLTRSMRADLGVMISASHNPYEDNGIKLFGPDGFKLSDEVEHEIERLIDSDLQKRLSASADLGRAKRIESVHARYIEFAKRTLPRNITLDGLRVVVDCANGAAYRVAPETLWELGAEVIAIGTEPDGFNINRDVGSTAPDALVRKVRELRADIGIALDGDADRVLVVDEKGQRVDGDQLMAVVARSWKEDERLTQPGIVATIMSNLGLERYLGGLGLSLVRTAVGDRYVLEHMREHGYNLGGEQSGHIIMSDYATTGDGLVAALQLLTVVQRQKRPVSEVCHCFDPLPQVLKNVRYGAGEPLRKDSVVTAIEGARQRLGNAGRLVIRPSGTEPVIRVMAEGDDRDLVVEVVDEVVEALRKAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: ASND1_SCHPO
Sequence: MCGILFALAEDRDNLLESPSFSALRKRIRARGPDFFGKHKLNSGPWNLHFESSVLHLRGPSDHLTPQPHVDSFGNVLCWNGEIWQINHSDHHKFTLNRNENDGAKLFELLNNNPGDIEKILGSIQGPFAFVYYQVRTNTLWWGRDRLGRRSLLYSLRDSNFVLSSVGNSSDFREVEPGFHSVQVDLIPKINFSKSLMQLEKTNPLPPVDESFLMGSISSDTVDTLHTYLIKALQDRVLTIPKLCSSNLDCSHYSRVCVLYSGGVDCGVLARLMHDIVPNNESIDLINVAFENPRFTETYRDRETGLLPDNFDAYDVCPDRQTGLQGWQELISVCPARKWNFVAINVPYTEVCEAQEIVKTLIYPNDSVMDLSIGLAFYFASQGRGVLLQNVDDIKLKHQLPSYTIKAKVLISGLGADEQLGGYMRHLRAFERKGMAGLEEELQLDIDRIPHRNLGRDDRVMSNQGKEVRYPFLDERLMALFSKMKTTDKMRLDLVGGDKLILRELGRRLGCPLASQEKKRAIQFGSKAAKMTPGTGRTSGRKKLEVCI
What are the official names of this protein?
Asparagine synthetase domain-containing protein C4F6.11c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: URE3_BRADU
Sequence: MNLSPREKDKLLISMAAIVARRRLDRGVKLNHPEAIAIISDFILEGARDGRTVAELMQSGAQVLTRDQVMPGIPEMIHDIQVEATFPDGTKLVTVHEPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_NICSY
Sequence: MTRSLKKNPFVANHLLKKIDKLNTKAEKEIIVTWSRASTIIPTMIGHTIAIHNGKEHLPIYITDSMVGHKLGEFAPTLNFRGHAKSDNRSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SPC34_YEAST
Sequence: MGESLDRCIDDINRAVDSMSTLYFKPPGIFHNAILQGASNKASIRKDITRLIKDCNHDEAYLLFKVNPEKQSVSRRDGKEGVFDYVIKRDTDMKRNRRLGRPGEKPIIHVPKEVYLNKDRLDLNNKRRRTATTSGGGLNGFIFDTDLIGSSVISNSSSGTFKALSAVFKDDPQIQRLLYALENGSVLMEEESNNQRRKTIFVEDFPTDLILKVMAEVTDLWPLTEFKQDYDQLYHNYEQLSSKLRFIKKEVLLQDDRLKTMSQYHPSSSHDVAKIIRKEKDEIRRLEMEIANLQE
What is the function of this protein?
Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation.  The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore.  The DASH ring complex may both stabilize microtubules during chromosome attachment in anaphase A, and allow the chromosome to remain attached to the depolymerizing microtubule in anaphase B.  Microtubule depolymerization proceeds by protofilament splaying and induces the kinetochore-attached ring to slide longitudinally, thereby helping to transduce depolymerization energy into pulling forces to disjoin chromatids.
What are the official names of this protein?
DASH complex subunit SPC34, 34 kDa spindle pole component protein, Outer kinetochore protein SPC34.
What is the protein family that this protein belongs to?
Belongs to the DASH complex SPC34 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and the kinetochore.
Protein: SYGB_SHELP
Sequence: MKFENLLIEVGTEELPPKSLRTLAESFLANFEEELQKAELSYESATWYAAPRRLALKVNALVTAQADKVVEKRGPAIAQAFDADGNPTKAAMGWARGNGITVEQAERLTTDKGEWLLHKAKVVGVETKSLVAEMAQRALDKLPIPKPMRWGSNKTQFIRPVHTVTMLMGDELIPGELLGIESARTIRGHRFMGVDTLELDHADNYLTALETQGKVMADYQARMAIIKADAQAAADAMGGIAEIDEDLLEEVTSLVEWPVVLTANFEEKFLDVPAEALVYTMKGDQKYFPVFDKAGTLLPHFIFVSNIESKDPAQIIAGNEKVVRPRLADAEFFFETDKKHSLESRLASLETVVFQQQLGTIKDRVERISALAAFIAQGIGADSEQAGRAGLLSKSDLMTNMVMEFTDLQGTMGMHYARLDGETEAVALALEEQYKPKFSGDSVPTQPISISVALAEKLDTLVGIFGIGQAPKGAADPFALRRAAIGILRICVENNLPLDLVDLVAKAQELHGANLSNADTAEQVLEFLMGRFRAWYQDQGISVDVILAVLARRPTSPADFDSRIKAVTHFRSLEQAAALAAANKRVSNILAKVEGDIASDIDSNLLQESAEQALASKLNELQPQLEPLFANADYQQALALLASLRESVDTFFEDVMVMADDEALKQNRLALLSKLRAQFLHAADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYE1_DICCH
Sequence: MKNTRVRSIGTKSLLAAVVTAALMATSAYAAVETDAATTGWATQNGGTTGGAKAAKAVEVKNISDFKKALNGTDSSAKIIKVTGPIDISGGKAYTSFDDQKARSQISIPSNTTIIGVGSNGKFTNGSLVIKGVKNVILRNLYIETPVDVAPHYESGDGWNAEWDAAVIDNSTNVWVDHVTISDGSFTDDKYTTKDGEKYVQHDGALDIKKGSDYVTISYSRFELHDKTILIGHSDSNGSQDSGKLRVTFHNNVFDRVTERAPRVRFGSIHAYNNVYLGDVKHSVYPYLYSFGLGTSGSILSESNSFTLSNLKSIDGKNPECSIVKQFNSKVFSDKGSLVNGSTTTKLDTCGLTAYKPTLPYKYSAQTMTSSLATSINNNAGYGKL
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.
What are the official names of this protein?
Pectate lyase E.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family. PLBC subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPO5_ARCFU
Sequence: MKFKLQDHMLVPKHEVLSKEEAEELLKILGIGKEQLPKIKADDPIAKEIGAKPGDIVKITRKSLTAGESVFYRLVV
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo5, DNA-directed RNA polymerase subunit H.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOAT_HUMAN
Sequence: MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWSHIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVDGDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGVYVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVTGFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLIDGFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGPMDCHRALEPVGHITSCE
What is the function of this protein?
Transports sulfoconjugated steroid hormones from the extracellular compartment into the cytosol in a sodium-dependent manner without hydrolysis (PubMed:17491011, PubMed:23667501, PubMed:24717977, PubMed:28951227).  Steroid sulfate hormones are commonly considered to be biologically inactive metabolites, that may be activated by steroid sulfatases into free steroids (PubMed:23667501, PubMed:24717977).  May play an important role by delivering sulfoconjugated steroids to specific target cells in reproductive organs (By similarity).  May play a role transporting the estriol precursor 16alpha-hydroxydehydroepiandrosterone 3-sulfate (16a-OH-DHEAS) at the fetal blood vessel endothelium (PubMed:24717977).  Can also transport other sulfoconjugated molecules such as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes (PubMed:17491011).
What are the official names of this protein?
Sodium-dependent organic anion transporter, SOAT, Solute carrier family 10 member 6, SLC10A6.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: RRAAH_HALH5
Sequence: MSQAEIDFITQFRTIPTTCISDALDGLTNLTSTIKPLNENDQVVGPARTVQVASGDNLAVLKAMYEASPGDVIVIDAKGDCTRAIAGDFVLGMAKTLGIAGFVVDGAIRDIRASKALNFPIFCRGTTIAASKKTGIGNINVPISCGGVPIRPGDLIVGDADGVTVIPKGQEENVLQKAKKKQADDEARERAISDNVMAIRAYLEKMIHPS
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: DEF_CHLAB
Sequence: MIRELEYYGSPTLRRKAEAILEITDEIRQLAQDMYETMVAHKGVGLAAPQVGESVSLFVMCVEGETEDGDLIFCDFPKVYINPVLSNVSEDLVLGREGCLSIPGLRADVYRPRSITVKAINLDGQEFTEHLEGFPARIVMHENDHLNGILYIDKMEEPKDYKKFKSALEKIRRRYNNHITDKAS
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: RL23_KOCRD
Sequence: MSVIYNKDPRDVIIRPVVSEKSYGLIDEGKYTFQVDPSANKTEIKYAIEHIFGVKVASVNTLNRPGKRKRTRFGWGQRKATKRAVVSLREGSIDIFGGPLS
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.