PharMolix/UniProtQA huggingface dataset:
Protein: ARP2_METAF
Sequence: MASSEETPRSLAGKVALVTGAGRGIGKGIALELAKRGASLVINYNSAEKPAQEVVDEIAKTGSRAVAIKADITKVPEVSRLFQEALQHFGHLDIVVSNSGTEVFKPEEEVTEEDYDRVFNLNTRAQFFIAQHAYVHLRNGGRIVLMSSVAANMSGIPNHALYAGSKAAVEGFTRSFAVDAGHKKITVNAIAPGGVKTDMYDANAWHYVPNGKPGMPMEEIDKGLAAFCPLGRVAVPQDIGRVVAFLAHPDSEWVNGQVILLTGGSVT
What is the function of this protein?
Hydroxynaphthalene reductase-like protein; part of the Pks2 gene cluster that mediates the formation of infectious structures (appressoria), enabling these fungi to kill insects faster (PubMed:29958281).  The product of the Pks2 gene cluster is different from the one of Pks1 and has still not been identified (PubMed:29958281).
What are the official names of this protein?
Hydroxynaphthalene reductase-like protein Arp2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: UREF2_BRUA4
Sequence: MPMHSPALPMLHLMRLVSPSQPVGAFSYSRGLEWAVHAGTVTNEESCAGWVFGLLEHSYAVLDGAIFWRMISALMRNDDAEFCRLNDWLGASRESSELELEDRRMGESLRTLLSELGVERARSFASEQRATYPAAFSIAACHWNIEPVDALRGLMWSVVESQIMAAIRLVPLGHTAGQRILIAGAAKIERAVEKARTLNDDEIGNTAPALAMASAWHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF 2.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAR5_ARATH
Sequence: MIVSFLYFSSLFPTSLRKINLVAGEKHKDRRMKPSLMDSLLGLLRIRIKRGVNLAVRDLNSSDPYVVVKMAKQKLKTRVIYKNVNPEWNEDLTLSVSDPNLTVLLTVYDYDTFTKDDKMGDAEFGIKPFVNALKMHLHDLPSGTIVTTVQPSRDNCLAEESRVIWSDGKLVQDIVLRLRHVECGEVEAQLQWIDLPGKGL
What is the function of this protein?
Stimulates the GTPase/ATPase activities of Obg-like ATPases (By similarity).  Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (PubMed:25465408).
What are the official names of this protein?
Protein C2-DOMAIN ABA-RELATED 5.
What is the protein family that this protein belongs to?
Belongs to the plant CAR protein family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus.
Protein: RS14Z_ALKCK
Sequence: MAKKSMIAKQKRTPKYNVQAYTRCERCGRPHSVLRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: VF407_ASFK5
Sequence: MEDTTFLEGANLAGITTLMNNLHINEQANLEELEKQVMGKQQNFPTDHFDEELNGLAKSLGINFNDPEFSLDSAHSVISKKPSRGGSDMISRDGLRHDGLRRDSVCTDSICSESVCSGSMRSGSMRHGSIRNGSVRDGSVRSGRTRRGPARSSSSRNDRIHSYSLSTHRKKYAESEASQKTVISKRDRKHHYAESEYSEKSIKPSTKQVDRLINHLRSNGDPNSFYKKEHDYDRKTKLVKLEKINMLLTYLGNEQISTDGIKIPTIDSSMQEIDDAIEMLTLRNVGIRYSSIAEEILIGLARGLEIVFDGTREIPFLNYRPDYTGLHNTFMIKLFKMRYETSQVVGNFVQNMSPLSKICLELGPSLLLYPALIRTKHKASEDLYNLLQKGPEDPFTAYNEIHETLKKNNK
What are the official names of this protein?
Uncharacterized protein B407L, pB407L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B407L family.
Protein: KDM6B_MOUSE
Sequence: MHRAVDPPGARSAREAFALGGLSCAGAWSSCPPHPPPRSSWLPGGRCSASVGQPPLSAPLPPSHGSSSGHPNKPYYAPGTPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESEHDSEEAVCCYHRALRYGGSFAELGPRIGRLQQAQLWNFHAGSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRSAEPPVVQPMPPAALSGPSGEEGLSPGGKRRRGCSSEQAGLPPGLPLPPPPPPPPPPPPPPPPPPPPLPGLAISPPFQLTKPGLWNTLHGDAWGPERKGSAPPERQEQRHSMPHSYPYPAPAYSAHPPSHRLVPNTPLGPGPRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPAASTACVPYAPSRPPGLPGTSSSSSSSSSSNNTGLRGVEPSPGIPGADHYQNPALEISPHQARLGPSAHSSRKPFLTAPAATPHLSLPPGTPSSPPPPCPRLLRPPPPPAWMKGSACRAAREDGEILGELFFGAEGPPRPPPPPLPHRDGFLGPPNPRFSVGTQDSHNPPIPPTTTSSSSSSNSHSSSPTGPVPFPPPSYLARSIDPLPRPSSPTLSPQDPPLPPLTLALPPAPPSSCHQNTSGSFRRSESPRPRVSFPKTPEVGQGPPPGPVSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQQQEAGVAPPPPLKEPFASLQPPFPSDTAPATTTAAPTTATTTTTTTTTTTQEEEKKPPPALPPPPPLAKFPPPPQPQPPPPPPASPASLLKSLASVLEGQKYCYRGTGAAVSTRPGSVPATQYSPSPASGATAPPPTSVAPSAQGSPKPSVSSSSQFSTSGGPWAREHRAGEEPAPGPVTPAQLPPPLPLPPARSESEVLEEISRACETLVERVGRSAINPVDTADPVDSGTEPQPPPAQAKEESGGVAVAAAGPGSGKRRQKEHRRHRRACRDSVGRRPREGRAKAKAKAPKEKSRRVLGNLDLQSEEIQGREKARPDVGGVSKVKTPTAPAPPPAPAPAAQPTPPSAPVPGKKTREEAPGPPGVSRADMLKLRSLSEGPPKELKIRLIKVESGDKETFIASEVEERRLRMADLTISHCAADVMRASKNAKVKGKFRESYLSPAQSVKPKINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGLFSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSFQESLQEERESEDEESEEPDSTTGTSPSSAPDPKNHHIIKFGTNIDLSDAKRWKPQLQELLKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAGTVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKISDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILFVTSENGSRNTYLVHCEGCARRRSAGLQGVVVLEQYRTEELAQAYDAFTLAPASTSR
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code.  Demethylates trimethylated and dimethylated H3 'Lys-27'.  Plays a central role in regulation of posterior development, by regulating HOX gene expression.  Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation (PubMed:17825402).  Plays a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression by acting as a link between T-box factors and the SMARCA4-containing SWI/SNF remodeling complex (PubMed:21095589).
What are the official names of this protein?
Lysine-specific demethylase 6B, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, [histone H3]-trimethyl-L-lysine(27) demethylase 6B.
What is the protein family that this protein belongs to?
Belongs to the UTX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSI_XYLFA
Sequence: MSSSSIEDIKGKSHRLRGSLLESLANPTTGALHESDQTLIKYHGSYQQDDRDLREERRRQKLEPAYQFMIRTRTPGGVITPQQWLQLDAIATRYANHSLRVTTRQAFQFHGVIKRELKATMQAINAALIDTLAACGDVNRNVQVAANPLLSRAHADLYTDAAHLSEHLLPNTRAYYEIWLDEKKVAGAGEEEEPIYGPHYLPRKFKIGFAAPPINDVDVFANDLGFIAVIVDNTLLGYNVAIGGGMGTTHGDPDTWPRVGNIIGFITRADLIAISTAIVTTQRDFGNRTLRKRARFKYTIDDRGLDCIVGEIQQRAGITLQPARPFVFEHNGDRYGWIEGEDRHWHLTLSLPAGRIADTESSPLLSGFRAIAQLGIGQFRMTPNQNVVIAGISPGQRATIDALVTQYGLDTGNRAPTALARHAMACVALPTCGLAMAEAERYLPDFNVKLQPILEKYGLAEKPILLRISGCPNGCSRPYLAEIALVGKAPGRYNLMLGGDQRGQRLNTLYRENITETEILAALEPLLGRYQQKRLPGEGFGDFLHRTGIIALPPYPTHRHVISSTLQA
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: QUEC_POLSJ
Sequence: MHTSALVLFSGGQDSTTCLAQALSKYERVETVAFDYGQRHKVELDARLNVLREIKSRFPHWAPKLGEDHLLDLAVLGQVSDTSLTRDVAFKMENSGLPNTFVPGRNLLFLTLAAALAYRRDLQVLVTGVCETDFSGYPDCRDDTIKAMQLALSLGMDKRFLIETPLMWIDKADTWRLAHALGGQALVDLIIEHTHTCYLGDRTHRQAWGYGCGACPACELRARGYERYAAALSKP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: PHNX_PSYIN
Sequence: MNSTINNDINNDINNDINNDINNTQSNSPIEAVIFDWAGTIVDFGSFAPTTIFVESFQKEYDFAITLQEARVPMGLGKWDHIQAVGKLPSVATRWQAQFGKAMDNADIDQIYNTFIPLQKVKVVDHADPILNAINVVNDLKKQGIKIGSCSGYPRAVMDVLIPAAAENGYLPDCVVATDDLPYGGRPAPHMALKNVIELGVNSVTNCIKVDDSTPGIEEGHNAGMWTVALLLSGNEAGLTAQEYQQASVQTLNKAREKARLIMKKSNPHYLIDTINDLPAVIKEIELRLIKGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: TRPE1_HALMA
Sequence: MQSVETDRTTFTDLAADAHPAARVPVEVRVDVDDPFLAYRRARDETGGVYLATTGGQSGWGYFGTAPADFREVDPRAGGTLAALTEFLDGERLVRGDCDVPYPCGAVGWLSYDVARELESLPDSADADRALPNLQVARYDRFAAWEEPRGESVTLRVTACPRVDDFETPELAYEFGKQHALDLARAAAQGDPSVEDPPVETDEATFESDCTRESFADRVQTVKQYIRDGDTFQANVSQRLRAPAAVHPVEAFDALRTVNPAPYSALLEFPGVDLVSASPELLLHRDGDRIETEPIAGTRPRGETPDADDRLETDLLDDEKERAEHAMLVDLERNDLGKVSKFGSVEVSDYRRVDRYSEVMHLVSVVEGRLRDGASLQDAIAAVFPGGTITGAPKPRTMEIIDEVEATRRGPYTGSIGLFGFDGRATLNIVIRTLVRYAEEYHLRVGAGVVHDSDPDREYQETLDKGRALVNAVDEALGRRVDLAMEDQQ
What are the official names of this protein?
Anthranilate synthase component 1 1, Anthranilate synthase component I 1.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: PAN3_NEUCR
Sequence: MAATRYNSGDLRRQVGSPRAKNRDTKETLCRNVVIYGHCRWEDSGCTFNHDQNKASVSQTDLNSNRRVFNVESPSFTPANQQQSAGKKSTFSSQAASAAPFTPRGVGTSTPTLQQANDSTIFNPAAIREFTPQNYDVGNTISQNGAQHVTQDGGLYSDPFSISSLGQTMPPQGQYNPYANDPNNLAGAGAGLYQPAGFGNGLVHPPNYHLYQPPSELYRPSLQPYQRTTYDFFIPKDRRENLQKKLFHMQQLLPNSGLPNLDRWHSLFPLDTKATRNSTCFGYPSWMYKAQNNKNGRHFALRRIEGYRLTNEKAILNVTKEWKKIINANIVTVHEAFTTEFFGDSSLIFVYDFHPLSETLYDHHFPPNNSHNRLRNTNKIPENLLWSYVCQIANALLAIHNAKLAARCLELSKIIWENNRIRLAACSILDVLHHDSPNRKTIEELQQEDFVKFGRIILALATNTPTLNFNNIDAALATIVPRYSTQLRGVLEWLIKPSAPGETKTVETLLGGITTHLANFANFVMQESDEKEFHLMRELENGRIARLMFKLSVVNERGDSCGVHNWSETGERLLLKLFRDYVFHQVDADGKARLDTNHYLNCLSKLDASSEEQILLTSRDNATVFVVSYRSIRQMLDRAYGELGKESKPSATGATI
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pabp-1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by rgb-30/xrn1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.  par-2/pan3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit par-1/pan2 to mRNA via its interaction with RNA and with pabp-1.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit pan3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_ACIAD
Sequence: MLLEFTKMHGLGNDFVVLDLISQRAYLDTTTIQRMADRHFGIGFDQLLIVEPPDYPNVDFKYRIFNADGSEVEQCGNGVRCFARFVHERQLTKKTKIKVQTKAGIVEPELGPNGWVRVNMGYPKFMPHEIPFVTEEFEALYTLELANEQSLKIDVVNMGNPHAVTIVPDVLTADVATMGPQVESHVRFPQRVNAGFMQIVDEKHIRLRVFERGVGETLACGTGACAAAVSGMRRGLLANEVEVELAGGKLQIAWQEGDVVWMTGPTANVYEGRLDLRYFQS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_KLEP3
Sequence: MQFDPPLQPAILLKRYKRFLADVITPDGRELTLHCPNTGAMTGCAAPGDTVWYSTSDNAKRKYAHTWELTETQQGAVICVNTLRANSLAKEAISSGIIPELSGYNQLKSEVKYGEENSRIDIMLQADDRQNCYIEVKSVTLAEKEYGYFPDAVTTRGQKHLRELMAVAANGDRAVILFAVLHSAIDRFSPAHHIDARYAQLLTEARDKGVEILAWKAELSTTKMTLNKPIAVVLNPGK
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: NOP14_DEBHA
Sequence: MAGSQLKQLKAALKANGLIGQTNIKKKNKKSKTPSETRRNDKQEILSNIRKDFNLFDGKINRTKRDVTMIQGGKFVKVGSKQHSDATRAKSDVENSMKLQYELDKKQHGKTGGLVDRRFGENNRNLTAEEKMLERFTRERQGTSKKKINFALGSDDEQDDEDNDGFVLTHSGKSLSLDNDLDDSKSNTKYYDEDSLMPEEVQPKRKSKQEVMKEVIAKSKFYKHQRQMEFQKAQDEIMNLDDEFGDIMTEFNNNPAKKPQSFSNKTPEEIEYDNKVRELTYDRRSVPADRTKTADELQKEHDTRLQKLEADRLRRMNGDYDDREAEADDLEGFWNGSEDEEEGFAIDNSAEEEGSSSGNEDDMDQSKPSGRTLKKTIIQIPGTHEDFIASLSSVDESNHCNYIKKVIETYQPRLAEGNKERMNVFVGILFKHILHLANDPCPPAENINETMKILKKLSESYNEKLVEVIRVEINDIQERIFNLQPRDLVYFVMVGYLFSTSDHYHLVVTPTLILMNESISSIPYDKKTTVSRIGQGLFIVDILLNYQTFSKRFTPEIVCFLEKAALLLIPEPEKLTNQSLSINKIIKSDTNLRTKGIKPTEDLVKVSELFGNDSQVLKLKLTNKLIDIFARILSIWRDNEVMIEILSSFSNLANHLSIHYNSPKLNQLIEKMSKIQNNLIKERKPLTLQHHKAISIATFAPKFEENFNPDKKSYDVNRERQELNKIKNQIKKERKSTLKDIRKESKFTARQQIADKKDKYDEYHKKMANIVNSISTIEGAEKNTYEREKQRRKNK
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity).
What are the official names of this protein?
Probable nucleolar complex protein 14.
What is the protein family that this protein belongs to?
Belongs to the NOP14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LSM2_ENTBH
Sequence: MLFFEYFKSQLNNEIIVNLKNDISISGILKNVDPFLNIKIENVIAISTNEFIKINKSITNIQLCSIRGSAIKSVELKKNGLEEHMVEATRIKCNLDC
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.  LSM2 binds specifically to the 3'-terminal U-tract of U6 snRNA.  Required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA (By similarity).
What are the official names of this protein?
Probable U6 snRNA-associated Sm-like protein LSm2.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFA_PSEAB
Sequence: MTELALILVSAILVNNFVLVQFLGLCPFMGVSRKIETAIGLSLATTFVLTLAAMCSHILQRYVLRPLDLEYLRTIGFILVIAVVVQFTEMLVKKTSPLLYRVLGIFLPLITTNCIVLGVALLNANKAEYGFLQATTQGFGAGLGFSLVLVLFAALRERIAIADVPAPFRGAAIGMITAGLMSLAFMGFSGLVRP
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PDLI7_HUMAN
Sequence: MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHAFSHV
What is the function of this protein?
May function as a scaffold on which the coordinated assembly of proteins can occur.  May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues.  Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e. g.  embryonic flat bones mandible and cranium), and endochondral bone formation (e. g.  embryonic long bone development).  Plays a role during fracture repair.  Involved in BMP6 signaling pathway (By similarity).
What are the official names of this protein?
PDZ and LIM domain protein 7, LIM mineralization protein, LMP, Protein enigma.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Colocalizes with TBX4 and TBX5 to actin filaments (By similarity).
Protein: COAX_LEPCP
Sequence: MSFLAIDIGNTRLKWGLYDAAKPGARLLAHGAVFLETIEQLAEQDWARLPHPTAMLGCAVAGDAVRRRTEEQLELWDLTPHWVVSQPVGGGIVNGYDHPSRLGSDRWVAMVGARERILEQTGPGARPVPAIVVMVGTAVTVDAVDPDGCFIGGLILPGFGLMLKALEMGTAGLRVPTGDVCEFPTNTSDALMSGGACGIAGAIERMHRQLQQRCGVAPRILMSGGAATKLAQIMALPVEVVDTLVFDGLLRLASDRVAAGLA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_BACFR
Sequence: MDFKYDVIVIGAGHAGCEAAAAAANLGSKTCLITMDMNKVAQMSCNPAVGGIAKGQIVREIDALGGYMGLVTDQTAIQFRILNRSKGPAMWSPRAQCDRNKFIWAWREILENIPNLHIWQDTVKEIIVENGEVVGLKTFWDVTFHARCIVLTAGTFLNGLMHVGKTQLPGGRMAEPASYKLTESIAKHGIEYGRMKTGTPVRIDGRSVHYELMDTQDGECDFHKFSFMNTSVRHLKQLQCWTCFTNEEAHNVLRNGLADSPLFNGQIQSIGPRYCPSIETKIVTFPDKEQHQLFLEPEGETTQELYLNGFSSSLPMEIQIEALKKIPAFKDLVIYRPGYAIEYDYFDPTQLKHTLESKKIKNLFFAGQVNGTTGYEEAGGQGIIAGINAHINCHGGEPFTLARDEAYIGVLIDDLVTKGVDEPYRMFTSRAEYRILLRMDDADMRLTERAYKLGLVKEDRYALLKSKREAVENIVNFTRNYSIKAALINDALENLGTTPLRQGCKLIDLINRPQITIENISEYVPAFKRELDKITDERKEEILEAAEILIKYEGYIGRERIIADKLARLESIKIKGKFDYDSLQSLSTEARQKLKKIDPETIAQASRIPGVSPSDINVLLVLSGR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_MYCUA
Sequence: MSKNSKAYRAAAEKVDRSNPYTPLQAAKLAKETSSTKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGEKADAAVAAGADIVGSDDLIEKIQGGFLDFDAVIATPDQMAKVGRIARVLGPRGLMPNPKTGTVTPDVAKAVADIKGGKINFRVDKQANLHFVIGKASFEENKLAENYGAAIDEVLRLKPSASKGRYLKKITVSTTTGPGIPVDPSVTRNFTEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: MYG_URILO
Sequence: MGLSDQEWQHVLTIWGKVESDLAGHGHQVLMRLFQDHPETLDRFEKFKGLKTPDQMKGSEDLKKHGVTVLTQLGKILKQKGNHESELKPLAQTHATKHKIPVKYLEFISEAIIKVIAEKHASSFGADSQAAMKKALELFRNDMASKYKEFGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RISB_SYNFM
Sequence: MKIYEGKLLAQGLRFGIVVSRFNDFIGERLLGGALDALKRSGAEEKNIDVFKVPGAFEIPLVAKKAASTGRYDAVICLGAVIRGATPHFDYVANEVSKGIAHAGLEAGVPISFGVLTTDTIEQAIERAGSKSGNKGWDAAVAAIEMANLIKQMS
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PYRE_HELPS
Sequence: MDIKACYQNAKALLEGHFLLSSGFHSNYYLQSAKVLEDPKLAEQLAKELAKQIQEAHLNIECVCSPAIGGILAGYELARALGVRFIFTERVDNTMALRRGFEVKKNEKILVCEDIITTGKSAMECAKVLEEKGAQIVAFGALANRGICKRVHSHLKAQEGACLPSHLPLFALEDFVFDMHKPSSCPLCTTSTAIKPGSRGN
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: LYTM_STAAM
Sequence: MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTLMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPATAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR
What is the function of this protein?
Peptidoglycan hydrolase (autolysin) specifically acting on polyglycine interpeptide bridges of the cell wall peptidoglycan.
What are the official names of this protein?
Glycyl-glycine endopeptidase LytM, Autolysin LytM.
What is the protein family that this protein belongs to?
Belongs to the peptidase M23B family.
What are the subcellular locations of this protein?
Secreted.
Protein: DACB1_MYCTU
Sequence: MAFLRSVSCLAAAVFAVGTGIGLPTAAGEPNAAPAACPYKVSTPPAVDSSEVPAAGEPPLPLVVPPTPVGGNALGGCGIITAPGSAPAPGDVSAEAWLVADLDSGAVIAARDPHGRHRPASVIKVLVAMASINTLTLNKSVAGTADDAAVEGTKVGVNTGGTYTVNQLLHGLLMHSGNDAAYALARQLGGMPAALEKINLLAAKLGGRDTRVATPSGLDGPGMSTSAYDIGLFYRYAWQNPVFADIVATRTFDFPGHGDHPGYELENDNQLLYNYPGALGGKTGYTDDAGQTFVGAANRDGRRLMTVLLHGTRQPIPPWEQAAHLLDYGFNTPAGTQIGTLIEPDPSLMSTDRNPADRQRVDPQAAARISAADALPVRVGVAVIGALIVFGLIMVARAMNRRPQH
What is the function of this protein?
Probably cleaves the terminal D-Ala-D-Ala dipeptide of the peptidoglycan stem peptide (Probable).  Shows weak D,D-carboxypeptidase activity in vitro (PubMed:22906310).  Acts on the synthetic penta-peptide substrate Penta-DAP (L-Ala-gamma-D-Gln-DAP-D-Ala-D-Ala) (PubMed:22906310).  The catalytic domain binds weakly to peptidoglycan in vitro (PubMed:25551456).
What are the official names of this protein?
D-alanyl-D-alanine carboxypeptidase DacB1, D,D-carboxypeptidase DacB1, DD-carboxypeptidase, DD-peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S11 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: FENR2_BACCN
Sequence: MTENQNVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKVRAQELVDNLKEQMKKFDPTICLEEAVETLEKQADGVFKLVTNKQTHYSKSVIITAGNGAFQPRRLELDGAQKFEKKNLHYFVDDMNKFARKRVVVFGGGDSAVDWTLMLEPIAEQVTIIHRRDKFRAHEHSVENLINSRADIKTPYVPVELIGEEQIEQVVLQHVKTEEKVVIDVDDVIVNYGFVSSLGPIKNWGLNIQKNSIVVNSKMETNIPGIYAAGDVCTYEGKVKLIACGFGEAPTAVNNAKAYFDPSAKLQPMHSSSMF
What are the official names of this protein?
Ferredoxin--NADP reductase 2, FNR 2, Fd-NADP(+) reductase 2.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: RS7_BACC7
Sequence: MPRKGPVAKRDVLPDPMYNSKLVTRLINKMMVDGKKGKSQTILYNAFDIVSERTGKEPMEVFEQALKNIMPVLEVRARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLANEILDAANNAGASVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.