PharMolix/UniProtQA huggingface dataset:
Protein: Y5322_PSEPF
Sequence: MSWFRWDGDDLILECHLQPAARSDDFCGLHGDRLKIRLTAPPVEGKANAYLMGFLAKAFGVSKSQVSLLSGELNRQKRVRIGAPKKLPDLPGLCRP
What are the official names of this protein?
UPF0235 protein Pfl01_5322.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: CH60_HYDCU
Sequence: MAKDVRLGLDAREKMVEGINVLADAVKVTLGPKGRNVVLEKSFGAPTVTKDGVSVAREIELEDKFMNMGAQMVKEVSSQTNDVAGDGTTTATVLAQSIVREGMKSVAAGMNPMDLNRGIHKAVEAVVKEIQKMSVPCTTTESIAQVGTISANSDSAVGKMIAEAMEKVSTEGVITVEEGSSLHDELVVVEGMEFDRGYLSPYFVTNQEKMVAELDNPYILLHDKKISNIRDLLPTLEAVSKAGRPLLIIAEDVDGEALATLVINNMRGIVKATAIKAPGFGERRKAMLQDMAVLTGGTVISEEVGLTLENVTLDMLGETKSAVVGKDSTKLIDGAGAKADIEARCAQIRSQAENTTSEYDSEKLQERLAKLAGGVAVIKLGAATEVEMKEKKDRVDDALHATRAAVQEGIVAGGGVALVRARSKVKVKGDNDEQQLGIEIALRAMEEPMRQIAANCGLEGSVIVNKVMESKDNMGFDAASETYVDMIKAGIIDPAKVTRSALQNAASVAGLVLTTGAAIADLPSKDGASADAAAGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PANK4_RAT
Sequence: MAECRASGGGSGGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHPGKDAEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAASSGLMSTAPELCPTQRARSGTFDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESVDAAERAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPQFGFEEAKRKLQERPWLVDSYTKWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLCRGIEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSPPCLDLSRLDKGLAVLVRERGADLVVIEGMGRAVHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYEVPAE
What is the function of this protein?
Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway.  Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms.  Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein.  May play a role in the physiological regulation of CoA intracellular levels.
What are the official names of this protein?
4'-phosphopantetheine phosphatase, Inactive pantothenic acid kinase 4, rPanK4.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the damage-control phosphatase family. Phosphopantetheine phosphatase (II) subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNPC2_MOUSE
Sequence: MKPPQRRRRVPARYVGEATGPTAWSPREMRHLLRLLQARRGQPEPDAAELAQELRGRSEAEICRFIQQLKGRVVREAIQKMQPGGREGPRHQGTPLPAPVEVWMDLAEKLTGPMEEALTAAFSQVLTIAAAEPLSLLHSRPGKPTKARGKALVFLSNQDGQKDPASEGSGPVPMTAADPTREASVSDPKASGANPETSGLASEVTVPDPDAPTKSLAGSSTERDLAVDFEKIYKYLSFSSRGGHGPELSAAESAVVLNLLMALPEELSHLPCTALLEHMTKTYAQLMAPQTALPGEKRPRPGTEDGGTGSTGPEEPDQASPQASEPIEPRLAWKAVGICPLNPFLVPLGLVSQAPSPSR
What is the function of this protein?
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes.  Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes.  Recruits TBP and BRF2 to the U6 snRNA TATA box (By similarity).
What are the official names of this protein?
snRNA-activating protein complex subunit 2, SNAPc subunit 2, Small nuclear RNA-activating complex polypeptide 2, snRNA-activating protein complex 45 kDa subunit, SNAPc 45 kDa subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2054_BIFLS
Sequence: MLNIMEVHETNQMIEQEKLDVRTITMGISLLDCASDDVDKTCDNIYRKITTYAKDLVSTGKAIERDYGIPIVNKRITVTPISLVGASSCKTSEDFVKIAHALDKAAKEVGVDLIGGYSALVSKSMTPAEELLIRSLPQALSETDIVCSSVNVGSTKTGIDMNAVELLGHIIKDVAERTADNDSYGCVKFVAFCNVPDDNPFMAGGFHGVTEGDAVINVGVSGPGVVSRALDAAKGKDFEFLCETIKRTAFKITRVGQLVAQEASRRLGIPFGIIDLSLAPTPAVGDSVGEVLEKIGLEQVGAPGTTAALAMLNDQVKKGGIMASSYVGGLSGAFIPVSEDKNMIDAASSGCLTLEKLEAMTCVCSVGLDMIAIPGDTSASTISGLIADEAAIGMVNQKTTAVRVIPVEGKGVGEMANFGGLMGYAPIIPVNQTSCEAFVTRGGRIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein Blon_2054/BLIJ_2131.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: PEX6_KLULA
Sequence: MVIASLESTHAISTSIVLSSDLWTEFYGTESVSSASPNYVKLTLPSYNKWHHQALISHCDNDDSLPFGSAGLPTNFIKQSQVRPMFSSIEIEPYVQQLPNLDNLVLSLNPDLFNELNQLSKEEQRKFLTLRFNLLFGITVLNVNQVVYPAFCKVTSSSNDFGILTDQTQIVLVPDSNVVEQSRSNDEFTEFDHLFSLHVKIQSLLDPVPVEFLSPPQPDTTDNDLFAFVQPNILLQLGVPSGTFVRVIAEEQEMLVQLFVLFAPNEYECDSLYVSPRVRYVFMNHARVIIQRPNLALNRFSVSNAVTLSRIGCQINAQRRYQDIISHHLALYFSEKQRIVKVGDLIPITFDSNYASMFTDDIRSGQHDTLVWFKVEEIESDSNEEYHIIDSSITRLSTVKITSRELMPKSICDYDRFYNLSPLFHYDEDAFPFAKRLKDILNTAIKCSARNVNVGTSIMLHSSSPNVGKTMLTRSVCAELGFHLIHVDCLSLTSNSNTSDATNKTIGYIRAKIETIISYVEKVVIFLSHLETILEDEQNQQDNTSSKMARQMNVEMADLIEEYTTKYKGTVFVGSTNDIDNIPAIVRSRIKFEIDVPVPTEKQRLQMFRWYFDPYVLNSQTPKLRSLISHNVPLQTVSVQSAGLTPMDIRSIVKAVKYKCYQRLKQNDLLIDMTDITAVINIARDRFSDSIGAPKIPNVTWDDIGGMDVVKGEIMDTIDMPLKHPELFSSGMKKRSGILFYGPPGTGKTLLAKAIASNFSLNFFSVKGPELLNMYIGESEANVRRVFQKARDAKPCVIFFDELDSVAPKRGNQGDSGGVMDRIVSQLLAELDGMSSGGDGVFVIGATNRPDLLDEALLRPGRFDKMLYLGISDTDKKQANIIKALTRKFTLESGIDILDIAKKCPFNYTGADFYALCSDALLNAMTRVAGEVDEKWEKYNMENKKNISLRYWFDNVANENDLKVVVKLQDFELAQQNLIPSVSEDELRHYLRLKSSFESQ
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-6', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
What are the official names of this protein?
Peroxisomal ATPase PEX6, Peroxin-6, Peroxisomal biogenesis factor 6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: HIS6_BORBR
Sequence: MNASRIAAAGASTLTRRIIPCLDVTAGRVVKGVNFVNLTDAGDPVEIARRYNEQGADELTFLDITATSDGRDLILPIIEQVASQVFIPLTVGGGVRQVSDVQRLLNAGADKISINSAAVANPELVRAAADYHGSQCIVVAIDARRSSAEGEPARWEVFTHGGRKATGLDAVAWARRMAAYGAGEILLTSMDRDGTKSGFDLELTRAVSDAVPVPVIASGGVGNLQHLADGVTTGRASAVLAASIFHFGQHTVRECKQYMAERGIAVRLT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_RHORT
Sequence: MVPPIPPRPLRAHRSTPLSGRIRVPGDKSISHRALMLGGLAVGRTEIRGLLEGEDVIATAHAMEAMGARIDRQETADGAGVWTVDGVGVGGLAEPADVLDMGNAGTGARLLMGLLATHDLTAILTGDASLRGRPMKRVTDPLALFGASFVGRSGGRLPMAVRGTATPLPVSYRVPVPSAQVKSAVLLAGLNTPGETTVIEPVATRDHTERMLGHFGAALRLGRDDQGATTITLTGQPELRAAPVEVPADPSSAAFPLVAAVLVPESHVTLAGVGMNPQRIGLIDTLREMGADILIRDPRIEAGEPVADLEVRASALTGIEVPAARAPSMIDEYPILAVAAACARGTTRMHGLGELRVKESDRLSAVATGLAACGVDVTVDGDTLIVHGKGTVPKGGATVAVNLDHRIGMAFLVLGLVSAEAVTIDDGRAIDTSFPGFVTLMTGLGAPISLI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPUB_BACSU
Sequence: MQVLTGLLEQYGYAVLFIVLMLELLALLGPGEFAGVLVFQEKLNWVLSMLAAGLGSCGSEHVVLDRV
What are the official names of this protein?
Uncharacterized protein YpuB, ORFX1.
Protein: PLIN3_PONAB
Sequence: MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHVKTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTERVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSGEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQALSLMETVKEGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEKAPEEKK
What is the function of this protein?
Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.  Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
What are the official names of this protein?
Perilipin-3, Mannose-6-phosphate receptor-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the perilipin family.
What are the subcellular locations of this protein?
Lipid droplet. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Membrane associated on endosomes. Detected in the envelope and the core of lipid bodies and in lipid sails.
Protein: GE_HHV2H
Sequence: MARGAGLVFFVGVWVVSCLAAAPRTSWKRVTSGEDVVLLPAPAERTRAHKLLWAAEPLDACGPLRPSWVALWPPRRVLETVVDAACMRAPEPLAIAYSPPFPAGDEGLYSELAWRDRVAVVNESLVIYGALETDSGLYTLSVVGLSDEARQVASVVLVVEPAPVPTPTPDDYDEEDDAGVTNARRSAFPPQPPPRRPPVAPPTHPRVIPEVSHVRGVTVHMETLEAILFAPGETFGTNVSIHAIAHDDGPYAMDVVWMRFDVPSSCADMRIYEACLYHPQLPECLSPADAPCAVSSWAYRLAVRSYAGCSRTTPPPRCFAEARMEPVPGLAWLASTVNLEFQHASPQHAGLYLCVVYVDDHIHAWGHMTISTAAQYRNAVVEQHLPQRQPEPVEPTRPHVRAPHPAPSARGPLRLGAVLGAALLLAALGLSAWACMTCWRRRSWRAVKSRASATGPTYIRVADSELYADWSSDSEGERDGSLWQDPPERPDSPSTNGSGFEILSPTAPSVYPHSEGRKSRRPLTTFGSGSPGRRHSQASYPSVLW
What is the function of this protein?
The heterodimer gE/gI serves as a receptor for the Fc part of host IgG.  Dissociation of gE/gI from IgG occurs at acidic pH.  May thus be involved in anti-HSV antibodies bipolar bridging, followed by intracellular endocytosis and degradation, thereby interfering with host IgG-mediated immune responses (By similarity).
What are the official names of this protein?
Envelope glycoprotein E, gE, gE-2.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein E family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host cell junction. Host Golgi apparatus membrane; Single-pass membrane protein. Host endosome membrane; Single-pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN), maybe through an interaction with PACS-1 sorting protein. The heterodimer gE/gI then redistributes to cell junctions to promote cell-cell spread later in the infection (By similarity).
Protein: PLOD2_HUMAN
Sequence: MGGCTVKPQLLLLALVLHPWNPCLGADSEKPSSIPTDKLLVITVATKESDGFHRFMQSAKYFNYTVKVLGQGEEWRGGDGINSIGGGQKVRLMKEVMEHYADQDDLVVMFTECFDVIFAGGPEEVLKKFQKANHKVVFAADGILWPDKRLADKYPVVHIGKRYLNSGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKVYIDPLKREAINITLDHKCKIFQTLNGAVDEVVLKFENGKARAKNTFYETLPVAINGNGPTKILLNYFGNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNVSIGVFIEQPTPFLPRFLDILLTLDYPKEALKLFIHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEENLSQAEARNMGMDFCRQDEKCDYYFSVDADVVLTNPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGALSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVYLIKGKTLRSEMNERNYFVRDKLDPDMALCRNAREMGVFMYISNRHEFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKYINRDYSKIFTENIVEQPCPDVFWFPIFSEKACDELVEEMEHYGKWSGGKHHDSRISGGYENVPTDDIHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRPHHDASTFTINIALNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIAVSFIDP
What is the function of this protein?
Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens.  These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.
What are the official names of this protein?
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2, Lysyl hydroxylase 2, LH2.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
Protein: UGPC_BURMA
Sequence: MAALSLKGVKKSYGGAQYVLHGIDVDIADGEFVVLVGPSGCGKSTLLRMIAGLETVTEGEIAIGGRIVNALEPKDRDIAMVFQNYALYPHMTVAQNMGYGLKIRGVERALIDARVQAAAQILELGPLLARRPRELSGGQRQRVAMGRAIVREPSVFLFDEPLSNLDAKLRVQMRLEIQRLHARLATTSVYVTHDQIEAMTLAQRVIVMNRGDAEQIGAPVDVYEKPATTFVASFIGSPAMNLLHGRLSEDGAAFDVADGPRLPVAGAAGAGRGIAPGREWILGVRPEHMTPQPGEAFATLAVDSCELLGADNLAHGRWGAHDVAVRLPHAMRPTRGETLPVALPARHLHFFDPATGKRAG
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYA_CALMQ
Sequence: MPILNESLLRTRIFIGRGFRRSRCPYCGHHYWTLNPSQDNCGDQPCTPYGFIGNPPGTYRPESIKDVRERFLSFFEKRGHTRVARYPVVARWRNDVYLVGASIYDFQPWVTEGVVPPPANPLTISQPSIRLTDVDKVGRSGRHLTGFEMMAHHAFNFPGKEIYWINETVEYAHEFFTRELGFRDDEVTYKENIWEGGGNAGESFEVLVRGLELATLVFMHYRVIGDEYREMPIRIVDTGYGLERIYWVLTGKPTIYEAVFEGFLNKARQLLGLPKPDEKVLASLAIHMGQLDPEVLALDKAYVEVAKRIGIDSSELINFIKPQEALYVLADHSRTVSWMINDGVIPSNSGVGYLARLLIRRMLKYMHVIGAQVPLTEIFNTHLNYLINDYPELKESMQLILDLVDLEEAKYKSAISQLPKLISRIKGELTINDLINLYDSHGIPPEVVRDEAAKRGVKVNVPDNFYEMLAARHQKPAKGEEGNRLDVTADDVIDLPPTRELFYEDTYAFEGKAKVLKVIKGKYIVLDSTIFYPEGGGQPADRGVLRFNGVEAKVVDVQRVGPVIVHVIDGPTPGVGDVVEMRIDSERRLGLMRMHTGTHILLQSIRRVLGKHVWQAGAQKDIPLSRLDVTHYRLPTPDEVKRIEELANEVVLSDLPVKAELMPRNEAEAKYGFIIYQGGVVPGGEVRIVKVGEGNDTYDVEACGGTHLDRTSRIGLIKIVKVDKIQEGVIRFIFTTGKYALDYVRNLEGKLDSAASKLRVGRDEVDEAVDRLIKELNNAEERSRVLARKAIEADLANIVKSMITVSGFKVAVYYEDYWVRDYLQELASKYPGDVLVLIHGNEYQVYTNGKVKAIDVAKVLNELGGKGGGSGTFAQGVFNNPVKQDDVVNTIKRKLTLTQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_SALPK
Sequence: MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVLEIVSGASRGIRLLQEEEDGLPLVGRVAAGEPLLAQQHIEGHYQVDPSLFKPSADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKKQGNKVELLPENSEFTPIVVDLREQSFTIEGLAVGVIRNGEWL
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: DHCR7_BOVIN
Sequence: MAAKSQPSAPKTKSTSGLTNGNAAAQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMACDQYGCSLTVPVADLATGRARLADIWARTPPVTAKAAQIYTAWVTLQVLLYMLLPDFCHKFLPGYVGGVQEGAVTPAGAVNKYEINGLQAWLLTHLLWFANAHLLGWFSPTIIFDNWIPLLWCANILGYTVSTFAMVKGYLFPTDARECKFTGNFFYNYMMGVEFNPRIGKWFDFKLFFNGRPGIVAWTLINLSFAAKQQELYGHVTNSMVLVNILQAIYVLDFFWNETWYLKTIDICHDHFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLPTYYALGVLLLGLLGYYIFRMTNHQKDLFRRTDGRCLIWGRKPKAIECSYTSADGQRHHSKLLVSGFWGVARHFNYTGDLMGSLAYCLACGGGHLLPYFYIIFMAILLTHRCLRDEHRCANKYGRDWEHYTAAVPYRLLPGIF
What is the function of this protein?
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway.
What are the official names of this protein?
7-dehydrocholesterol reductase, 7-DHC reductase, Sterol Delta(7)-reductase.
What is the protein family that this protein belongs to?
Belongs to the ERG4/ERG24 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: URE2_SYNPV
Sequence: MAPFIPGELLPEPGEIELNAGRPVTSLHVANSGDRPVQVGSHFHFAEANAALQFDRTAARGQRLDIPAGTAIRFEPGDSRDVNLIPFAGDRRVIGFNGQINGPLDA
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALBU_RABIT
Sequence: MKWVTFISLLFLFSSAYSRGVFRREAHKSEIAHRFNDVGEEHFIGLVLITFSQYLQKCPYEEHAKLVKEVTDLAKACVADESAANCDKSLHDIFGDKICALPSLRDTYGDVADCCEKKEPERNECFLHHKDDKPDLPPFARPEADVLCKAFHDDEKAFFGHYLYEVARRHPYFYAPELLYYAQKYKAILTECCEAADKGACLTPKLDALEGKSLISAAQERLRCASIQKFGDRAYKAWALVRLSQRFPKADFTDISKIVTDLTKVHKECCHGDLLECADDRADLAKYMCEHQETISSHLKECCDKPILEKAHCIYGLHNDETPAGLPAVAEEFVEDKDVCKNYEEAKDLFLGKFLYEYSRRHPDYSVVLLLRLGKAYEATLKKCCATDDPHACYAKVLDEFQPLVDEPKNLVKQNCELYEQLGDYNFQNALLVRYTKKVPQVSTPTLVEISRSLGKVGSKCCKHPEAERLPCVEDYLSVVLNRLCVLHEKTPVSEKVTKCCSESLVDRRPCFSALGPDETYVPKEFNAETFTFHADICTLPETERKIKKQTALVELVKHKPHATNDQLKTVVGEFTALLDKCCSAEDKEACFAVEGPKLVESSKATLG
What is the function of this protein?
Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs.  Its main function is the regulation of the colloidal osmotic pressure of blood.  Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity).  Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity).  Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity).  The shared binding site between zinc and calcium at residue Asp-273 suggests a crosstalk between zinc and calcium transport in the blood (By similarity).  The rank order of affinity is zinc > calcium > magnesium (By similarity).  Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E. coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E. coli (By similarity).  Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).
What are the official names of this protein?
Albumin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: TSN9_SALSA
Sequence: MARGCLCCVKYMLFLFNLLFWLGGCGLLGVGVWLSVSQGSFATLSPSFPSISAANLIITLGAVIMVTGFLGCLGAIKENKCLLLSFFITLLVILLAELILLILFFVYTDNVSENARQDLKEGLALYSTNNNAGLRNAWNTIQTEWHCCGVNGYTDWHTALQEKVVPDHCCQDIYQDCGRNATNQFWTRGCYEKVEEWLDDNKHLLGTIAMCVLVIQLLGMAFSMTLYQQIHRSGKKYEA
What are the official names of this protein?
Tetraspanin-9, Tspan-9.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS15_ACIF2
Sequence: MALSHDIKAEVVQGYATHVGDTGSPEVQVALLTTRIEGLTDHFKVNKHDHHSRQGLLRMVGQRRKLLDYLKKRDVNRYRTLIERLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GPPA_ENT38
Sequence: MMITGSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLSQDNHLSPEAMERGWQCLRLFAERLQDIPHNQIRVVATATLRLAVNSVDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGDDRRLVVDIGGASTELVTGTGAQATSLFSLSMGCVTWLERYFTDRNLAQENFDEAENAAREVLRPVMDKLRYHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFSELDIHCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNVQRRFIVDTEQAQRVAQLASSFANQLKTTWALEPLSQDLLISACALHEMGLSIDFKQAPIHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNTVDLSSLHQQNAVPPRVAEHLCRLLRLAILFASRRRDDLLPAIKLEAEGENLTLTLPEDWLDNHPLGAEMIEQEYQWQSYVHWALEVK
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: Y3293_AZOVD
Sequence: MAAKVEPFWKRKTLDRLDAEEWESLCDGCGLCCLQKLEDEEDGSVYYTRIACRLLDLETCRCRDYANRRRSVPDCIQLTPAQAGEFQWLPPTCAYRLLAEGEDLPLWHPLVCGDPQAVHRERISRAGRMLSESAVAEDDWEEHLIFRAG
What are the official names of this protein?
UPF0260 protein Avin_32930.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.
Protein: DXR_SHESA
Sequence: MQNMVILGATGSIGASTLSVISANPDAYRVYALVANASVDKMLALCVTHRPQVAHMVDSQAALALQAKLPPELNIQVTSGEDELIALVTATEVDTVMAAIVGAAGLVPTLAAVKAGKRVLLANKEALVMSGELFIEATKASGATLLPVDSEHNAIFQCLPEEVQANLGRCDLAASGISHILLTGSGGPFLTAELASLASMTPAQACKHPNWSMGPKISVDSATMMNKGLEFIEARWLFNTQKDQLKVVIHPQSVIHSMVQYRDGSVIAQMGNPDMRTPIAHCMSYPQRIRSGVEPLDFFKVGQLSFCEPDFNRFPCLALAIAACAQGQEATTVLNAANEIAVEAFLQGQIGFTHIAKVNEACLSSVPKRAMTSIDDIIALDAQTRIYAREQLAKFA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: IWS1_CANAL
Sequence: MSDPLADYTNLSHDEIDPSSANAAESEQAEPEQQVSEHYEPQPEELTYENDENVLNSIKVQKITDAEAIGEVVRKKVIRDSRPQGYQQDDFNDNSNVTLGSRPGHQQTDEIDISSMDPQQRKRFELEERMSAAIKPSNKRRRKADEDDLERMQDDKIDYLKDQMIKAANSDVEKNSQGQIATEKLKLLKEVSDILARADLAIPILDNNLLEAVRLWLEPLPDASMPAYQIQKELIHALETLPIKTDHLVASGIGKVLVFYQRSKRTEPSLKKIVDRLIGDWTRPILNKSDSYKDRTVQFHEYNRNKFTNKLSRGVKKREAKTLYEENAERRKRAAIPSTRTTAYKIAPQVDKSLLMRQQSRHASNDERFKRINSKLTSMSVKRKAAKKGGPSIEGRDLAM
What is the function of this protein?
Transcription factor involved in RNA polymerase II transcription regulation.  May function in both SPT15/TBP post-recruitment and recruitment steps of transcription (By similarity).
What are the official names of this protein?
Transcription factor IWS1.
What is the protein family that this protein belongs to?
Belongs to the IWS1 family.
What are the subcellular locations of this protein?
Nucleus.