PharMolix/UniProtQA huggingface dataset:
Protein: LAMB4_HUMAN
Sequence: MQFQLTLFLHLGWLSYSKAQDDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRAQKYCILSYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHVSIRLDLEALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQAQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLHTLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTWTGPGFARVLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWTVQIVVNPPGGSEHCIPKTLQSKPQSFALPAATRIMLLPTPICLEPDVQYSIDVYFSQPLQGESHAHSHVLVDSLGLIPQINSLENFCSKQDLDEYQLHNCVEIASAMGPQVLPGACERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTCLQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRGNVSEIERILKHPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAVYEFQDLKDTIERAKNEADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINETSSTINTSANTRNDLLTILDTLTSKGNLSLERLKQIKIPDIQILNEKVCGDPGNVPCVPLPCGGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQAEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDIHLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEFVELKKQYAILQRKTSTTGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILEDQVVAIKNEIVEQEKKYARCYS
What is the function of this protein?
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
What are the official names of this protein?
Laminin subunit beta-4, Laminin beta-1-related protein.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: PTH_MESHJ
Sequence: MKLIVGLGNPGEKYAKTKHNVGYWVLDLLAEKLALSFDQKTENGIYVKQPDFILAKPTTFMNKSGDFVEELIKFYKINTQDLMIIYDDMNFEVGQAAIKTTGSAGGQRGMAHIIEKCKTKEIKRLKIGISRGENAKEYVLSPFLPKDNAKIKLVIEEAANILIFYLSNSFITTIEKFNANKNKV
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_EUDCH
Sequence: MAPNLRKSHPLLKTINNSLIDLPTPSNISAWWNFGSLLGICLATQILTGLLLAAHYTADTTLAFSSVAHTCRNVQYGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLYKETWNTGIILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFTLHFLLPFMIAGLTLIHLTFLHESGSNNPLGIVANSDKIPFHPYYSTKDILGFILLLLPLTTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPLLHKSKQRTMTFRPLSQLLFWTLVANLTILTWIGSQPVEHPFIIIGQLASLTYFTILLILFPLIGTLENKMLNH
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ACTG_PENCH
Sequence: MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPINPKFNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFSLPHAISRVDMAGRDLTDYLMKILAERGYTFSTTAEREIVRDIKEKLCYVALDFEQEIQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFQPNVLGLESGGIHVTTFNSIMKCDVDVRKDLYGNIVMSGGTTMYPGISDRMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, gamma.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CP27A_RABIT
Sequence: MAALGCARLRWALLGPRVAGCGLCPQGARAKAAIPTALPADEAAQAPGAGPGDRRRRRSLEELPRLGQLRFFYQAFVQGYLLHLHKLQVLNKARYGPMWVSYLGPQLFVNLASAPLVETVMRQEGKYPVRNDMQLWKEHRDHQDLAYGVFTTDGHDWYQLRQALNQRLLKPAEAALYTDALNEVIDSFVVRLDQLRAESASGDQVPDMADLLYHFALEAICYILFEKRIGCLEASIPKDTENFIRSVGLMFQNSVYVTFLPKWTRPLLPFWKRYLDGWDTIFSFGKNLIDQKLQEVVAQLQSAGSDGVQVSGYLHSLLTSGQLSPREALGSLPELLLAGVDTTSNTLTWALYHLSKNPEIQAALRKEVVGVVAAGQVPQHKDFAHMPLLKAVLKETLRLYPVIPANSRIIVDKEIEVGGFLFPKNTQFVFCHYVTSRDPSTFSEPDTFWPYRWLRKGQPETSKTQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQRYELMLAPETGEVQSVARIVLVPNKKVGLRFLPTQR
What is the function of this protein?
Cytochrome P450 monooxygenase that catalyzes regio- and stereospecific hydroxylation of cholesterol and its derivatives.  Hydroxylates (with R stereochemistry) the terminal methyl group of cholesterol side-chain in a three step reaction to yield at first a C26 alcohol, then a C26 aldehyde and finally a C26 acid (By similarity).  Regulates cholesterol homeostasis by catalyzing the conversion of excess cholesterol to bile acids via both the 'neutral' (classic) and the 'acid' (alternative) pathways (PubMed:2722778).  May also regulate cholesterol homeostasis via generation of active oxysterols, which act as ligands for NR1H2 and NR1H3 nuclear receptors, modulating the transcription of genes involved in lipid metabolism.  Plays a role in cholestanol metabolism in the cerebellum.  Similarly to cholesterol, hydroxylates cholestanol and may facilitate sterol diffusion through the blood-brain barrier to the systemic circulation for further degradation.  Also hydroxylates retinal 7-ketocholesterol, a noxious oxysterol with pro-inflammatory and pro-apoptotic effects, and may play a role in its elimination from the retinal pigment epithelium.  May play a redundant role in vitamin D biosynthesis.  Catalyzes 25-hydroxylation of vitamin D3 that is required for its conversion to a functionally active form (By similarity).
What are the official names of this protein?
Sterol 26-hydroxylase, mitochondrial, 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 26-hydroxylase, Cytochrome P-450C27/25, Cytochrome P450 27, Sterol 27-hydroxylase, Vitamin D(3) 25-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Post-translationally targeted to mitochondria. All three of the receptor proteins in the TOM complex, TOMM70, TOMM20 and TOMM22 are required for the translocation across the mitochondrial outer membrane. After translocation into the matrix, associates with the inner membrane as a membrane extrinsic protein.
Protein: FBIA_MYCSS
Sequence: MKVTVLVGGVGGARFLLGVQHLLGLGQFARDDARGPDAHELTAVVNVGDDTWMFGVRICPDLDTCMYTLGGGIDPDRGWGHRDETWHAKEELAAYGVQPDWFGLGDRDLATHLVRSQMLRAGYPLSQVTEALCDRWNPGARLLPASDDRSETHVVITDPDTDERRAIHFQEWWVRYRAKVPTHSFAFVGADKATTAPGVTDAIADADVVLLAPSNPVVSIGSILAIPGIRGALRSTSAKIIGYSPIIAGKPLRGMADECLSVIGVASTSEAVGRHYGARSGTGILDGWLVHEGDSAQIDGVQVEAVPLLMTDPATTAEMVRAGVRLAGVTL
What is the function of this protein?
Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
What are the official names of this protein?
Phosphoenolpyruvate transferase, EPPG:FO PEP transferase.
What is the protein family that this protein belongs to?
Belongs to the CofD family.
Protein: RM28_DROME
Sequence: MAHATPQGVKLLNGWKRPGRFDKGLGAQLPEAYRKFWREWKLTTPAAVHYIPKEQQWERDEVTHAIKPVQNIPLPLIDTPESHRGIWGGEAVIKGFQKREQTKRRVPHFWVPNLRRSVVHSHVLDCYMSVVVTERTLEQIHECHGFDHYLLKNRACDLRSALALKLKREVLQALQNGVPALADEPERQQEVLKEYRRYLEPYTPEEIDWYGHTYLEAIRKLQKQLREAEKVVPHKLEFRGKLIEQLRQAGISEAGKLEKPDALAAESSVEHKDSDIEALTKLESSPSSSWLSKINPFGKKET
What are the official names of this protein?
39S ribosomal protein L28, mitochondrial, L28mt, MRP-L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PTLI_BORPA
Sequence: MIHAHSNARLLRWAILAIAPVTLGACAPNGPPGLPYPDGKPLIPINTAAPEQGSSCQTRAP
What are the official names of this protein?
Type IV secretion system protein PtlI homolog.
Protein: PPCEL_HUMAN
Sequence: MQQKTKLFLQALKYSIPHLGKCMQKQHLNHYNFADHCYNRIKLKKYHLTKCLQNKPKISELARNIPSRSFSCKDLQPVKQENEKPLPENMDAFEKVRTKLETQPQEEYEIINVEVKHGGFVYYQEGCCLVRSKDEEADNDNYEVLFNLEELKLDQPFIDCIRVAPDEKYVAAKIRTEDSEASTCVIIKLSDQPVMEASFPNVSSFEWVKDEEDEDVLFYTFQRNLRCHDVYRATFGDNKRNERFYTEKDPSYFVFLYLTKDSRFLTINIMNKTTSEVWLIDGLSPWDPPVLIQKRIHGVLYYVEHRDDELYILTNVGEPTEFKLMRTAADTPAIMNWDLFFTMKRNTKVIDLDMFKDHCVLFLKHSNLLYVNVIGLADDSVRSLKLPPWACGFIMDTNSDPKNCPFQLCSPIRPPKYYTYKFAEGKLFEETGHEDPITKTSRVLRLEAKSKDGKLVPMTVFHKTDSEDLQKKPLLVHVYGAYGMDLKMNFRPERRVLVDDGWILAYCHVRGGGELGLQWHADGRLTKKLNGLADLEACIKTLHGQGFSQPSLTTLTAFSAGGVLAGALCNSNPELVRAVTLEAPFLDVLNTMMDTTLPLTLEELEEWGNPSSDEKHKNYIKRYCPYQNIKPQHYPSIHITAYENDERVPLKGIVSYTEKLKEAIAEHAKDTGEGYQTPNIILDIQPGGNHVIEDSHKKITAQIKFLYEELGLDSTSVFEDLKKYLKF
What is the function of this protein?
Serine peptidase whose precise substrate specificity remains unclear (PubMed:16143824, PubMed:16385448, PubMed:28726805).  Does not cleave peptides after a arginine or lysine residue (PubMed:16143824).  Regulates trans-Golgi network morphology and sorting by regulating the membrane binding of the AP-1 complex (PubMed:23321636).  May play a role in the regulation of synaptic vesicle exocytosis (PubMed:24610330).
What are the official names of this protein?
Prolyl endopeptidase-like, Prolylendopeptidase-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9A family.
Protein: NORM_BACLD
Sequence: MRETKDLREKARQFLTILIPILITQAGLSLITVLDTVMSGKVSAADLAGVAIGSSLWTPVYTGLAGILTAVTPMVAQLMGAKRQKDVPYTVIQSIYVAGIISLAVIVSGYFLIDPVLENLDLERKVAVIAKQYLICIGLGILPLFVYNVMRCFIDSLGKTRVTMLITLCSLPINFVLNYLFIFGNFGFPKLGGAGAGLASAITYWCICLISLYIVHKKTPFHQFRIFGTFYSFSFAESMKLLKIGIPIGFAIFFETSIFAAVTLLMSHFDTVTIASHQAAMNFASLLYMLPLSVSMTLTIVVGFEAGAKRFKDSRAYSYLGISIAVGFSLFTALIILLFREQIAGLYAADRDVLLLTKDFLLYALFFQLSDAIAAPIQGALRGYKDVNYTLVTALVSYWIIGLPVGFVIGTYTSFGAFGYWIGLITGLAAGAVGLFFRLKRIQNRYIHTQSM
What is the function of this protein?
Multidrug efflux pump.
What are the official names of this protein?
Probable multidrug resistance protein NorM, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CML16_ARATH
Sequence: MASTKPTDQIKQLKDIFARFDMDKDGSLTQLELAALLRSLGIKPRGDQISLLLNQIDRNGNGSVEFDELVVAILPDINEEVLINQEQLMEVFRSFDRDGNGSITAAELAGSMAKMGHPLTYRELTEMMTEADSNGDGVISFNEFSHIMAKSAADFLGLTAS
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Probable calcium-binding protein CML16, Calmodulin-like protein 16.
Protein: PURL_RHOOB
Sequence: MSAHPVDTVTAATATPDVAQPFKELGLKDDEYARIKEILGRRPTEAELAMYSVMWSEHCSYKSSKVHLRYFGETTTDEMRSSMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPIAVMDQLRFGAADAPDTRRVVDGVVRGVGGYGNSLGLPNIGGETVFDESYAGNPLVNALCAGTMRVEDLHLAFASGAGNKIILFGARTGLDGIGGVSVLASETFDGDESGTGRKKLPAVQVGDPFTEKVLIECCLELYAAKLVVGIQDLGGAGLSCATSELAAAGDGGMHINLEQVPMRATGMTAAEVLSSESQERMCAVVTPENVDAFMAVCKKWDVLATDIGEVTDGDRLTISWHGETVVDVPPRTVAHEGPVYERPVQRPASQDALVANTTAGLKRPESADELKATLLKMIASPALCSRKWITEQYDRYVRGNTVLAENADSGVIRVDEKTGRGIALATDASGRYTALDPYAGAQLALAEAFRNVAVTGATPKAVSNCLNFGSPEDPGVMWQFQQAVRGLADGCATLGIPVTGGNVSFYNQTGSTAILPTPVVAVLGVIDDVHRRIPTGLGLEPGETLILLGDTNDEFDGSIWSQVEHGHLGGVPPKVDLEREQLLADILLAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRILLPDDADPFVTLFSESSGRVLVAVPRTEETRFTGMCTARNLPWVRIGVVDEGSDSVEVQGQFSVSLAELRTTFEGTLPALFG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6551_RHOJR
Sequence: MAHNLALGAHGEDLAARYLTEAGMEIVDRNWRSRYGEVDLIAAEGDWLVFVEVKTRRGLGYGSPAEAVTFSKQRRIRLLAVEWLRDSGRHWSRVRFDVVAIMIGHGPQPQIEHVRDAF
What are the official names of this protein?
UPF0102 protein RHA1_ro06551.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: RL3_SHEPC
Sequence: MAIGLIGRKVGMTRIFTEDGVSIPVTVIEVAGNRVTQVKTLETDGYRALQVTTGTKKANRITKPEAGHFAKSGVEAGRGLWEVRLEDGEGEGIEVGAELNVDIFADVAKVDVTGQSKGKGFQGGVKRWNFRTQDMTHGNSLSHRSNGSIGQNQTPGRVFKGKKMSGHMGAERVTTQNLVVVRVDVERNLLLVRGAVPGATNGDLIIKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GATB_CAMHC
Sequence: MFETIIGLEVHCQLNTKTKIFCSCPTSFGDKANVHVCPTCLALPGALPVLNKEAVKKAIMFGTAVNATINKKSVFDRKNYFYPDLPKAYQISQFTIPIVEHGELFININGENKRIGITRAHLEEDAGKNTHEEGRSLVDLNRAGTPLLEIVSEPDMRSGDEAVAYLKKLHSILRFINISDANMQEGSFRCDVNVSIRPKGDEKLYTRVEIKNLNSFKFVQKAIEYEVARQIDAWEDGKYSELVVQETRLFDTSNFTTRSMRSKEDSAEYRYFPDPDLLTVEISDEMLEEARKIPELPNEKKERYINELGLKKDDAEVIISSYEHAKFFEDLINAGHEPKLCVTWLNVELNGRLKNGLTIEDSPIDSAKMSDLLSRIEDGTISQKAAKEVLDFIMENIEISVDDVIKKLGLKQVSDDATILAVIDAVISKNEQKVAEYRNGKDKLFGFFVGQVMKEGKGAFNPAKVNELLKQKL
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: TRET1_BOMMO
Sequence: MEMEIKDENLRNSVPFVRQLSTDSVKTKTEYDNEDGTPYKSTTQKLFLWTQLLAAFAVSVGSMNVGFSSGYTSPAVLTMNITLDITKEEITWVGGLMPLAALVGGIVGGPLIEYLGRKKTIMGTAVPFTIGWMLIANAINVVMVFAGRVICGVCVGIVSLAFPVYIGETIQPEVRGALGLLPTAFGNTGILLAFLVGSYLDWSNLAFFGAAIPVPFFLLMILTPETPRWYVSKARVQEARKSLRWLRGKNVNIEKEMRDLTISQTESDRTGGNAFKQLFSKRYLPAVMISLGLMLFQQLTGINAVIFYAASIFQMSGSSVDENLASIIIGVVNFISTFIATMLIDRLGRKVLLYISSVAMITTLLALGAYFYLKQNHIDVTAYGWLPLACLVIYVLGFSIGFGPIPWLMLGEILPSKIRGTAASLATGFNWTCTFIVTKTFQNIIDAIYMHGTLWLFAVICIGGLLFVIFFVPETKGKSLEEIEMKLTSGSRRVRNISKQPENIC
What is the function of this protein?
High-capacity facilitative transporter for trehalose.  Does not transport maltose, sucrose or lactose.  Mediates the bidirectional transfer of trehalose.  Responsible for the transport of trehalose synthesized in the fat body and the incorporation of trehalose into other tissues that require a carbon source, thereby regulating trehalose levels in the hemolymph.
What are the official names of this protein?
Facilitated trehalose transporter Tret1, BmTRET1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Trehalose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPSA_ENTAG
Sequence: MSSKGEQPLVLWYNQLGMHDVDRVGGKNPSLGEMITNLSSLGVSVPNGFATTSYAFNLFLD
What is the function of this protein?
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
What are the official names of this protein?
Phosphoenolpyruvate synthase, PEP synthase, Pyruvate, water dikinase.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
Protein: NCAP_INBAA
Sequence: MSNMDIDGINAGTIDKTPEETTSGTSGATRPIIRPATLAPPSNKRTRNPSPERATTSSEADIGRRTQKKQTPTEIKKSVYNMVVKLGEFYNQMMVKAGLNDDMERNLIQNAHAVERILLAATDDKKTEFQKKKNARDVKEGKEEIDHNKTGGTFYKMVRDDKTIYFSPIRITFLKEEVKTMYKTTMGSDGFSGLNHIMIGHSQMNDVCFQRSKALKRVGLDPSLISTFAGSTLPRRSGTTGVATKGGGTLVAEAIRFIGRAMADRGLLRDIKAKTAYEKILLNLKNKCSAPQQKALVDQVIGSRNPGIADIEDLTLLARSMVVVRPSVASKVVLPISIYAKIPQLGFNVEEYSMVGYEAMALYNMATPVSILRMGDDAKDKSQLFFMSCFGAAYEDLRVLSALTGTEFKPRSALKCKGFHVPAKEQVEGMGAALMSIKLQFWAPMTRSGGNEVGGDGGSGQISCNPVFAVERPIALSKQAVRRMLSMNIEGRDADVKGNLLKMMNDSMAKKTNGNAFIGKKMFQISDKNKTNPIEIQIKQTIPNFFFGRDTAEDYDDLDY
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: THIE_CHLL3
Sequence: MNSPHSPILCVITDEDTSPLDMVPRALRGGANMIQLRRKTASGRELCRLAEALIPFCRQAGALFIINDRADIALATDADGVHLGQDDLPVAAARQLFGPGKIIGASTSSVDEALKAERNGADYAGFGHIFPTGSKAKGYKPLGPEAISLAAAALRIPLIAIGGITRENAGPLISRGAAGIAVISAVTKAESPEEAARSLMAIMNTTRAGEGT
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RK21_ARATH
Sequence: MASSSATLSLCSTFSAHCNVNSRRSSTILCSLSKPSLNLAKPLTGFLSPSTASTSRTAFTVAPKFAESVVEAEPETTDIEAVVVSDVSEVTEEKAKREEIFAVIMVGGRQYIVFPGRYLYTQRLKDANVDDQIVLNKVLLVGTKTHTYIGKPVVTNATVHAVVESQGLNDKVVVFKYKPKKKYRRNIGHRQPNTRIRITGITGYEEYPASPNVAVGEVNL
What is the function of this protein?
This protein binds to 23S ribosomal RNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21, chloroplastic, CL21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LV949_HUMAN
Sequence: MAWAPLLLTLLSLLTGSLSQPVLTQPPSASASLGASVTLTCTLSSGYSNYKVDWYQQRPGKGPRFVMRVGTGGIVGSKGDGIPDRFSVLGSGLNRYLTIKNIQEEDESDYHCGADHGSGSNFV
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 9-49.
What are the subcellular locations of this protein?
Secreted. Cell membrane.