PharMolix/UniProtQA huggingface dataset:
Protein: ATPD_ACIC5
Sequence: MAAFAARYARAFADVVAEAHLPLEQVQQQLDDFMATWNGAADLREVFLDPSFPAEEKVAILDRMNQKLGLAPVVRNFLAVVLQHERMHAMEEILKEFREEMNRRLGITAVSITSARALNEAERKSLLEQVGTLAEGRVDASFHEDASLLGGVVVQIGSKVYDGSVRGRFARLEEQLAVR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HXD10_PANTR
Sequence: MSFPNSSPAANTFLVDSLISACRSDSFYSSSASMYMPPPSADMGTYGMQTCGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTYATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQMEKKMNEPVSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIXXDTPTSNWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRMKLKKMSRENRIRELTANLTFS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D10.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_LEPBJ
Sequence: MIIIPAIDLFDNCAVRLFKGNYKEKKIYSSEPWKLAEGFAKNGATLLHLVDLNGARNQLGINEDSILKIRKTTSLKVQLGGGIRDKEKLAYYDKIGIDRFILGTAAVTDPDLLKFALDNYGKERVVVAVDAIDGIVKIAGWEKDSGVRYRDLMDRLAKAGIEHIVFTDIAQDGTLAGPNLKAYQEILNSYPFQVIASGGISSLKDLMDLSSLKTKIPLYGVITGKALYEGKLDLAKAISSI
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIM1_METBF
Sequence: MHIFEGFLPGPWWQIWWILSIPVFAYGIFRLNKLVKEKPEVLPLIAVSGAVIFVLSSLKLPSVTGSTSHPTGTGMAVILFGPAITSVLSAIVLLYQALFLAHGGITTFGANLMSMGIIGPFVAYAIYKTMMRLNVNFYVSAFVTATLADWVTYVVTSTQLALAFPANPGGVEGSLVAFLSVFAITQIPLAILEASLITLLFKYVLQAKGDLMVRLDVLTDSQVRKLKETKA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Putative cobalt transport protein CbiM 1, Energy-coupling factor transporter probable substrate-capture protein CbiM 1, ECF transporter S component CbiM 1.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYF_PROM5
Sequence: MINFKKQIMKKTTFFLCAMLLVSSILIAPRSSLAYPFWAQQNYESPREATGKIVCANCHLAQMPTIAEVPQAVGADSVFKAVVKIPYKDDIKEIGADGSEVPLQVGAVVMLPDGFKLAPQERWTDEIKEETEGVYFTNYSEEKENIIIVGPLPGDTNKEIIFPVLSPNPATNKEYHYGKYSLHIGGNRGRGQVYPTGDKSNNVIFTSSSAGTINSIETIEDGSYQINIENENGEITTEAVPVGPKLIVKEQDQITVGAPLTSDPNVGGFGQLDAEVVLQSPYRIIGLIAFFIGVGLTQILLVLKKKQVEKVQAAEGI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RSMG_FRACC
Sequence: MTGLPDAPEVPPVAVEIFGTRTGSAARYVELLATDGVERGLIGPRETDRLWDRHVLNCAVLADVVPVQADVVDVGSGAGLPGIPLALARPDLRVVLLEPMERRCRFLHEVVATIGLEDQISVVRGRAPDAGIGPDGRRFGIAVARAVAPLERLGAILFPMLRPGGVMLAMRGSRILEELQDARSGLGTQGWHPVDVVRCGEGRVEEPARVLRAVRSSQRTRAESRGGRGDGERHDGRQVRRTSRDSLRSREVGRDQPTRGQSRST
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPY_CHLTR
Sequence: MRLCFILFLLLSPLISEASQHIITVKTIHEIASDILYDDANYWLIFDIDDVLFEGAEALSHSAWFERSIQGMRALGTSEQEAWDTLYPDWLSIQRQGSIKQIETAIPLLITKVQNQNKIVFAYSERKVCAQDVTLEQLAKINLSFEKANLPYTSLPSNICFTKGVLFGSEIHKGPGLQRFLDAQPSLPEKVIYIDNEKYNVLRIGEVCKQKNIPYLGIVYTASKYHPPIYLPDIARIQYLYRQKLISNEAAALLSRHRLDK
What are the official names of this protein?
Putative outer membrane protein CT_371.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: DER_AGRFC
Sequence: MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDAKLIDLRFTIIDTAGLEQSGPETLQGRMWAQTEAAIDEADVTLFVIDAKAGLTPADETLGEMLRRRGKPVVLVANKSEARGSDAGFYDAFTLGLGEPCPVSAEHGQGMIDLRDAIVEAIGEDMAFPPDVDEAETDIVLPRTEPGSEEEEDEEPVYDETKPLRVAIIGRPNAGKSTLINRFLGEDRLLTGPEAGITRDSISVEWDWRGRTIKMFDTAGMRRKAKVTEKLEKLSVADSLRSIRFAETVVIVFDSTIPFEKQDLQLVDLVIREGRAAVLAFNKWDLVEDPQAYLADLREKTERLLPQARGIRAVPMSGQTGYGLDRLMQSIIDTDKTWNRRISTAKLNRWLDAQTTQHPPPAVSGRRLKLKYMTQVKARPPAFMISCTRPEAIPESYTRYLVNGLRKDFDMPGVPIRVHYRGSDNPFESKAKKRR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RSMG_RHOJR
Sequence: MFHVEPNGGEPAEWDEQAAARQVFGERFDIAERYYKSLASDGVERGLIGPREVPRLWERHLLNCAVVGELIAEGESVVDVGSGAGLPGIPLAIARPDLRITLVEPLLRRSVYLAEFVESNGLDVLVVRGRAEESGVVKEAGGADVVTSRAVAPLEKLAKWSLPLIHEHGRMLALKGSSAAEEISRDRASLTRLGAGKLDIVECGVGLLPVPTVVVRAERVPKRRQRR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 518 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_CLOB8
Sequence: MKKYILALDQGTTSSRAIIFDKEQNILGVSQKEFTQIYPNQGWVEHNPLEIWASQYGVLQEVIAKTNITQEEVAAIGITNQRETTIVWDKNTGEPVYNAIVWQCRRTAGIIEELKLDKEFSEYVKENTGLLLDAYFSATKIKWILDNVEGARERAEKGELLFGTVDTWLVWKLTNGKVHVTDYTNASRTMLYNIKELRWDERILEKLNIPKSMLPEVKNSSEVYGYTNLGGTGGVRVPIAGMAGDQQCALFGQTCFEEGSVKNTYGTGCFLLMNTGEKMIHSKNGLVSTIAVGIDGKVQYALEGSVFVGGAVIQWIRDELKLVTDAADTEYFAQKVEDNGGVYVVPAFTGLGAPYWDMYARGAIFGLTRGANRNHIIRAALESIAYQSKDLIDAMQEDAGCKLTRLKVDGGASRNNLLMQFQADITGAEVVRPIITETTALGAAYLAGLAVGFWKSKEEIAEKWAVSQSYSPNLAEEKKEKLYKGWKKAVKRAEGWEEE
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: MBTP1_MOUSE
Sequence: MKLVSTWLLVLVVLLCGKRHLGDRLGTRALEKAPCPSCSHLTLKVEFSSTVVEYEYIVAFNGYFTAKARNSFISSALKSSEVENWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKFAESNPIVPCNETRWSQKWQSSRPLKRASLSLGSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNERTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKMDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRVKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQKRELVNPASVKQALIASARRLPGVNMFEQGHGKLDLLRAYQILSSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTIVNVTILNGMGVTGRIVDKPEWRPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHIMITVASPAETELHSGAEHTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHVHTNFRDMYQHLRSMGYFVEVLGAPFTCFDATQYGTLLLVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFVLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPSEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGLAPPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPHLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVALAFFVVQISKAKSRPKRRRPRAKRPQLAQQAHPARTPSV
What is the function of this protein?
Serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates include SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6, ATF6B and FAM20C.  Cleaves substrates after Arg-Ser-Val-Leu (SREBP2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu.  Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2.  Also mediates the first step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B).  Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.  Cleaves the propeptide from FAM20C which is required for FAM20C secretion from the Golgi apparatus membrane and for enhancement of FAM20C kinase activity, promoting osteoblast differentiation and biomineralization (PubMed:34349020).  Involved in the regulation of M6P-dependent Golgi-to-lysosome trafficking of lysosomal enzymes.  It is required for the activation of CREB3L2/BBF2H7, a transcriptional activator of MIA3/TANGO and other genes controlling mega vesicle formation.  Therefore, it plays a key role in the regulation of mega vesicle-mediated collagen trafficking.
What are the official names of this protein?
Membrane-bound transcription factor site-1 protease, Endopeptidase S1P, Sterol-regulated luminal protease, Subtilisin/kexin isozyme 1, SKI-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=May sort to other organelles, including lysosomal and/or endosomal compartments.
Protein: RS15_PSYA2
Sequence: MLTNADREQIIAQYQRGESDTGSPEVQVALLSARINDLQNHFKAHKADHHSRRGLIRMVNTRRKLLDYLKSKDLGRYTTLISQLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: COPB_DROME
Sequence: MTSQVPCYTIINSPDLEVTNEMQLKRDLEKGDTNVKIETLKRVIKLLLNGERYPGLIMTIIRFVLPVQNHTIKKLLLIFWEIVPKTSADGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIASFLDTQQDMSCKRNAFLMLLHADQERALNYLASCIDQVHTFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLNSSSNAVRYESAGTLITLSLAPTAIKAAASCYIELVVKESDNNVKLIVLDRLVAMKEHEGMEKVMQDLVMDVLRVLAAPDIEVRRKTLALALDLVYSRNIGEMVLVLKKEVAKTHNVEHEDTGKYRQLLVRTLHTCSIKFPDVAANVIPVLVEFLSDTNELAAADVLIFIREAIQKFPALRALIIEHLIEAFPQIKSSKIHRAAVWILGEYVEGSQILEVIAVIQQTLGEVPMVEAEQRRLAGDQTEEQKQQQGSAGGNAAGSAAEGSGSGNASNKVTSDGTYATQSAYSLAPVAKAEKRPPLRQYLMDGDFFIGAALSATLTKLALRYAELETEARAQNRLTTQVMLIMSSILHLGKSGFPSKPITNDDTDRIFVCLRTLSERTPEAISVFTLYCREALGKMLDAQHDEDQRMLKEKQKATAKVQPDDPVLFAQLSNGRDNQLGENVFESSLNQALAGSKNAQLSDVASPNSKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQNCTLELATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVYETALNTNVVVLNTIHIDIMDYIIPASCTDTEFRQMWQDFEWENKVTVNTSFTDLHEYLKHLLKSTNMKCLTPEKALSGQCGFMAANMYAKSIFGENALANLSIEKPVDDPDSKVTGHIRIRAKSQGMALSLGDKISSSQKQSVQAA
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  Required for limiting lipid storage in lipid droplets.
What are the official names of this protein?
Coatomer subunit beta, Beta-coat protein, Beta-COP.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it (By similarity). Present within the clusters of tubulo-vesicular structures of Golgi membrane and cis-Golgi membranes.
Protein: ACYP_THIDA
Sequence: MKTLHLQIEGRVQGVWFRESMRREAERLGVDGWVRNRPDGSVEAVVQGTDEAVAALVAWAKMGPPLAHVERVDLSETEGEYSGFEKRSD
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RL24E_SULIY
Sequence: MPTTRQCSFCGHEIPPGTGLMYVRNDGTILWFCSSKCRKSMLKYHRDPKKYKWTTRYMKVR
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: RPOE_ECOLI
Sequence: MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSGDVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIEAENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIAAIMDCPVGTVRSRIFRAREAIDNKVQPLIRR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase (RNAP) to specific initiation sites and are then released (PubMed:7889935, PubMed:2691330, PubMed:9159522, PubMed:9159523).  Extracytoplasmic function (ECF) sigma-E controls the envelope stress response, responding to periplasmic protein stress, increased levels of periplasmic lipopolysaccharide (LPS) as well as heat shock (PubMed:7889935) and oxidative stress; it controls protein processing in the extracytoplasmic compartment.  The 90 member regulon consists of the genes necessary for the synthesis and maintenance of both proteins and LPS of the outer membrane (PubMed:7889934, PubMed:11274153, PubMed:16336047).  Indirectly activates transcription of csrB and csrC, 2 sRNAs that antagonize translational regulator CsrA, linking envelope stress, the stringent response and the catabolite repression systems (PubMed:28924029).
What are the official names of this protein?
ECF RNA polymerase sigma-E factor, RNA polymerase sigma-E factor, Sigma-24.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. ECF subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with the inner membrane via RseA (PubMed:9159522, PubMed:11777003).
Protein: MNTP_METMA
Sequence: MSFLTNFLLGLGLAMDAFAVSMSSGTTVRPFKVSDALKLAVFFGGFQALMPVLGWVGGSAVSGFVSDYAPWIAFGLLAFIGGKMIYEALYGDPDGKVNSLNYSMLFLLAVATSIDALAVGISFAFLGTPILEPVIIIGCVTFVMSFCGAVLGYRIGHFFENEVEILGGLILIGLGVKILAEHMDWI
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPD17_HUMAN
Sequence: MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS
What are the official names of this protein?
Putative speedy protein E17.
What is the protein family that this protein belongs to?
Belongs to the Speedy/Ringo family.
Protein: RS281_ARATH
Sequence: MDSQIKHAVVVKVMGRTGSRGQVTQVRVKFTDSDRYIMRNVKGPVREGDILTLLESEREARRLR
What are the official names of this protein?
40S ribosomal protein S28-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS28 family.
Protein: RLMH_PHEZH
Sequence: MRISIVAIGRLARSPETELVKLYVERATNAGRALGLGPVEVVEVESRKPGKAAEAEALRAHLSDAHVIACDERGAARPSRAFAEEIGRLRDQGVRRLVFLIGGADGLDPALVAQANGKLAFGPQTWPHALARAMLAEQVYRAVSILAGSPYHRD
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_CORGL
Sequence: MTTRLYLSPTPPRNDREGASKSTSASIKHDAYLPPADGNRVLVDRFGRIARDLRVSLTDRCNLRCTYCMPAEGLEWLPTEQTLNDAEVLRLIRIAVVKLGIRQIRFTGGEPLLRKNLEDIIAGTAALRTDEGEKVHIALTTNGLGLDKRIAGLKEAGLDRVNISLDTIDAERYVSLTRRDRLSGVLASIDAAVAAGLHPVKINAVVMPGVNEVDIVPLAEYCISKGSQLRFIEQMPLGPREQWKRGDMVTAEEILARLEEKFTLSPAKEPRGAAPAALWNVVDKSNPDITGQIGIIASVTHPFCGDCDRSRLTTDGTIRNCLFSRTETPLRDALRDGASDDELAQLWAGAMWEKKPGHGIDDEGFLQPDRPMSAIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: TRHO_RICBR
Sequence: MSEKIAILSAYSFVNIEEPESLIPKLLFVGKRKYVKGTILLSKEGFNGSFSGSYESVNLVLEELKKLTNTKDVNVKINCSEIHPFQKLKVRLKKEIVAMNVDNLNVNLFKGEYIETKDWDEFITKQDVIVDTRNDYEVEVGTFKAAINPYTETFKQFPAWVEQNAELLKGKKIAMFCTGGIRCEKSTSLLKSMGHEEVYHLKGGILQYLEDTQNKNNLWQGECFVFDDRRAVADDLAPAEGYWLERK
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: NPY5R_RAT
Sequence: MEFKLEEHFNKTFVTENNTAAARNAAFPAWEDYRGSVDDLQYFLIGLYTFVSLLGFMGNLLILMAVMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKAMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELKETFGSALLSSKYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSHKENRLEENEMINLTLQPSKKSRNQAKTPSTQKWSYSFIRKHRRRYSKKTACVLPAPAGPSQGKHLAVPENPASVRSQLSPSSKVIPGVPICFEVKPEESSDAHEMRVKRSITRIKKRSRSVFYRLTILILVFAVSWMPLHVFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLRALIHCLHMS
What is the function of this protein?
Receptor for neuropeptide Y and peptide YY.  The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.  Seems to be associated with food intake.  Could be involved in feeding disorders.
What are the official names of this protein?
Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y841_HAEIN
Sequence: MKWIKKGTFSGKQYRDDVSRKISWGHWFAFFNIIVAIFIGARYAFIIDWPDTLAGKLYFFVSLLGHFSFNVFALYLLVVFPLSFIVKNHRTFRGLTVIFSTICTTLLLFDTAVFNRFNLHLSSVVWNLLVNPENGEMSRDWQIFFAPMPIILLAQMLFSRWSWEKLRSLERQKWLKGTGIFLTTTFIATHLIYAWADAYLYRPITMQRSNFPLSYPMTARSFLEKHGFLDGEEYTQKLAQEGRLDALKIDYPKKELTYAPITHKPNILLVTVSGLRHDAISNEKMPKLAKFATSSTEFTNHYSTGNSNNAGLIGLFYGLNANYTDSILSNHTQSVLIEKLRAENYQLGLFSATNFKDSIFRQALFREIKLSSNKTNKPNNESAVKNLNDFIKAQKTDSPWFAYLDLALEAKNPSDYDRTLQDIDSLLAKALESTPLENTLVIITSEHGLTFNEMNQKERENYFGRDEIQVPLLVYWKDLPVGKQNGLSNHADIFSALMQTVFRVENPLMDYSQGRNLFDLKGDDWVLASNFRWNVVIQPDGTQYHIDRKGNYKKFDKDYIEQSSDRPPLGIFLEAFQLQNFFFEK
What are the official names of this protein?
Uncharacterized protein HI_0841.
What is the protein family that this protein belongs to?
To E.coli YejM.
Protein: PUR9_LACAC
Sequence: MKRALISVSDKTNLVDFAKGLVQNGYEIISTGGTKKTLDEAGVKTISVEEVTNFPEILDGRVKTLNPYIHGGLLAKRDDLEHMATLEKLNIKPIDLVCVNLYPFKQTIEKPDVTTEEAIENIDIGGPSLLRAASKNYQDVTVVTDKNDYDLVLKEIAEKGNTTLETRAKLAAKVFRATAAYDAVIANYLTKQVGLEDPEKLTLTYDLKEKMRYGENSHQKAWLYEDAIPKSFSILQAHQLHGKKLSYNNIKDADEALRCIREFQDEPTVVAMKHMNPCGIGRGDTLEEAWDRAYEADSVSIFGGVIALNRKVDLATAKKMHKIFLEIIIAPGFDDDALEVLEKKKNIRLLKLDFSKENEPTRPEIVSVMGGILQQEQDTLVENTDDWKVVTNAQPTEAQLKTMMFALKAVKHTKSNAIVVANDERTLGVGAGQPNRIDSAKIAIKHAGDAIDDRAVLSSDAFFPFNDCVEYAAKHGIKAIVQPGGSIRDKDSIEIADKYGVAMVFTGYRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: RL34_METSB
Sequence: MKRTYQPSKLVRKRRHGFRARMATVGGRRIIAARRARGRKKLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TRPB_STAA9
Sequence: MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEEGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGGGSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALAIGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMAERGLAND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: MES1_ARATH
Sequence: MSEEKRKQHFVLVHGSCHGAWCWYKVKPLLEAVGHRVTAVDLAASGIDTTRSITDIPTCEQYSEPLTKLLTSLPNDEKVVLVGHSFGGLNLAIAMEKFPEKISVAVFLTAFMPDTEHSPSFVLDKFGSNMPQEAWMGTEFEPYGSDNSGLSMFFSPDFMKLGLYQLSPVEDLELGLLLMRPGSLFINDLSKMKNFSDEGYGSVPRVFIVCKEDKAIPEERQRWMIDNFPVNLVMEMEETDHMPMFCKPQQLSDYFLKIADKFV
What is the function of this protein?
Methylesterase shown to have carboxylesterase activity, methyl indole-3-acetic acid (MeIAA) esterase activity, methyl salicylate (MeSA) esterase activity and methyl jasmonate (MeJA) esterase activity in vitro.  Required to convert methyl salicylate (MeSA) to salicylic acid (SA) as part of the signal transduction pathways that activate systemic acquired resistance in systemic tissue.  MeSA is believed to be an inactive form that needs to be demethylated to exert a biological effect.
What are the official names of this protein?
Methylesterase 1, AtMES1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Methylesterase family.
Protein: 36011_ASFK5
Sequence: MLPSLQSLSKKVLAKQCIPVDQYHILKCCGLWWYDGPITFYTYRNKMFIKSTCFSEGIELNTVLMKAAKENNHDLIRLFVEWGADINYGLVCAHSEHTRNLCRELGAKDRLDREYILKIFFDTTRNKTDSNIILCHEMFSNNPNLKHVDDLDLREEIMWELRGLMEITYMLDHDNSFSNMLTKYWYAIAVDYGLKKAIHYFYQKYTHLHRWRLMCALFYNNVFDLHELYEIERVRMDIDEMMHIACIQDYSYSAIYYCFIMGANINQAMFVSIQNYNLGNMFFCIDLGANAFEEGKTLAIQKENYLIADALSLKHYNPVISLLSAVTDPEKINSMLKNYHSKNMVVFLDYERR
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.  In addition, inhibits the phosphorylation of host TBK1 and IRF7 and thereby negatively regulates the host cGAS signaling pathway and antagonizes IFN-mediated antiviral activity.
What are the official names of this protein?
Protein MGF 360-11L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.