PharMolix/UniProtQA huggingface dataset:
Protein: GEP3_LACTC
Sequence: MLPVSRLCVRSSLRKLVFVRFVSCTSCGVTLQNNNVRGTGFYTPPKAQIERKRPVIEDLKYLLFSQDLQSLKSELSAEERPKKNKPLICKRCNDALHHNTFSKEDFRRYSMQEVYRHVPAGADIYHVVPLTDFPLQLNSAVLKDSRYNSALLLSKGDQVTPDKSLLQRKAPQFFKDMLRLKMNYNSNKSIAFSASKGWNIQSVYSVLRSNSFLIGCPNSGKSTLVNALLKKFPSLKPSEGNNASEAEIVRGAGVSNIPNMTRDLQSYNIGSKVINDLPGYSTNYGSPGPEDALDAKVLEKIQKTHLFKKTKLVKQRYTSLKGTDAGRCYTVSGIFYLVPPPDTINQVVNYIPGNERQYRNIDKALSVVNSEHACPEKGPLRQYVGVQKAMESKDNYVRHVLPPFQGSIEVVLKEIGYFQLKTTGKYKFLGLHEVWVPKGVDVCIREPIARLIDEGYEGYLSSEGKKKAIPEKREVFSATYPMSFEETDTLQKMKEMFLERTKNDVLARKFISSNPLKIIGTAQKEAPNLYWYYKW
What is the function of this protein?
May be involved in the mitochondrial lipid metabolism.
What are the official names of this protein?
Genetic interactor of prohibitins 3, mitochondrial, Found in mitochondrial proteome protein 38.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CYCC_CLITE
Sequence: GVPCAESCVWIPCTVTALLGCSCKDKVCYLD
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cyclotide cter-C.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: MSRB3_PONAB
Sequence: MSPQRTLPRPLSLCLCLCLCLAAALGSAQSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPSFHDVISSEAITFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSAALSFTPADSSGAAEGESGVASPAQADKAEL
What is the function of this protein?
Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine.
What are the official names of this protein?
Methionine-R-sulfoxide reductase B3, MsrB3.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
[Isoform 1]: Endoplasmic reticulum. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion.
Protein: CYCLD_ANTCI
Sequence: HLPQVSSSLHSRAATSVVDLNGNEIQLHDMLSGHYLTTANAPVLESTALFNNNNNFNHDVVNGLNRDPSPTFPTKQAVKKDRHSKIYTSQGPRDRRVRLSIGIARKFFDLQEMLGFDKPSKTLDWLLTKSKTAVKELVQSKSTKSNSSSPCDDCEEVVSVESENVTDHSKGKSLKANNKCKEAMDSHQAAAKESRAKARARARERTKEKMCIKQLNEAIVLRNHQFEVSGTREAFVHPVFGFHQQNYGNTSHENWDQSNFASQSNQLCAIL
What is the function of this protein?
Involved in the dorsovental asymmetry of flowers.  Retards growth rate and reduces organ number in the dorsal region of flowers (By similarity).
What are the official names of this protein?
Transcription factor CYCLOIDEA.
What are the subcellular locations of this protein?
Nucleus.
Protein: VM3CX_DABSI
Sequence: MMQVLLVTISLAVFPYQGSSIILESGNVNDYEVVYPQKVTALPKGAVQQPEQKYEDTMQYEFEVNGEPVVLHLEKNKILFSEDYSETHYYPDGREITTNPPVEDHCYYHGRIQNDAHSSASISACNGLKGHFKLRGEMYFIEPLKLSNSEAHAVYKYENIEKEDEIPKMCGVTQTNWESDKPIKKASQLVSTSAQFNKIFIELVIIVDHSMAKKCNSTATNTKIYEIVNSANEIFNPLNIHVTLIGVEFWCDRDLINVTSSADETLNSFGEWRASDLMTRKSHDNALLFTDMRFDLNTLGITFLAGMCQAYRSVEIVQEQGNRNFKTAVIMAHELSHNLGMYHDGKNCICNDSSCVMSPVLSDQPSKLFSNCSIHDYQRYLTRYKPKCIFNPPLRKDIVSPPVCGNEIWEEGEECDCGSPANCQNPCCDAATCKLKPGAECGNGLCCYQCKIKTAGTVCRRARDECDVPEHCTGQSAECPRDQLQQNGKPCQNNRGYCYNGDCPIMRNQCISLFGSRANVAKDSCFQENLKGSYYGYCRKENGRKIPCAPQDVKCGRLFCLNNSPRNKNPCNMHYSCMDQHKGMVDPGTKCEDGKVCNNKRQCVDVNTAYQSTTGFSQI
What is the function of this protein?
Catalytic subunit of blood coagulation factor X-activating enzyme.  Activates coagulation factor X (F10) by cleaving the Arg-Ile bond and is also able to activate coagulation factor IX (F9) and protein S (PROS1) by specific cleavage of Arg-Ile and Arg-Val bonds.
What are the official names of this protein?
Coagulation factor X-activating enzyme heavy chain, Coagulation factor X-activating enzyme chain alpha, RVV-X heavy chain, Russellysin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIId sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BM2_INBSI
Sequence: MLEPFQILSICSFILSALHFMAWTIGHLNQIKRGVNLKIRIRNPNKETINREVSILRHSYQKEIQAKETMKEVLSDNMEILSDHIVIEGLSAEEIIKMGETVLEVEELH
What is the function of this protein?
Forms presumably a highly low-pH gated proton-selective channel.  Trp-23 may function as a minimalistic gate that opens and closes the pore.  When the environmental pH is lower than a threshold, the BM2 channel would be activated and selectively transport protons across the membrane from the extracellular side to the cytoplasmic side.  Crucial for the uncoating process.  When the virion is internalized into the endosome, the channel acidifies the virion's interior, promoting the dissociation of matrix protein 1 (M1) from the ribonucleoprotein (RNP) thus allowing the transport of the RNP from the virion into the cell's nucleus.  Also plays a role in viral protein secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation (By similarity).  Plays a crucial role in virion assembly.  Expressed in the late phase of the infection (By similarity).
What are the official names of this protein?
Matrix protein 2, BM2.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type III membrane protein. Host cell membrane; Single-pass type III membrane protein. Note=Transported to the plasma membrane through the trans Golgi network.
Protein: NADK2_PROMA
Sequence: MPRLGLILNDGKELALKAALSIESKLEKSGYEVVRVSSSGGMVGFANPDQHMRTLGYNACVPEGFDPSMKLAIVLGGDGTVLSAARQTAPVGVPILTINTGHLGFLSEAYLPDIDKALEQVLASQWEIEERTSLVVSVMRGEQRRWEALCLNEMALHREPLTSMCHFEISIGRHAPVDISADGVILSTPTGSTAYSLSAGGPVITPDCPVLQLTPIAPHSLASRALVFSDLEPVTVFPATPERLMMVVDGTAGCYVWPEDRVLIRKSNHPVRFIRLTDHEFFQVLRKKLGWGLPHVAKPEKY
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_ANOFW
Sequence: MMNVGQWLTRVRKESPLVHNMTNVVVTNFVANGLLAVGASPVMAYAKEEVADMVRLARALVLNIGTLNETDVEAMLIAGKAANEANIPVIFDPVGAGATAYRTETARRILREVNISILRGNASEIASIAGEQVRTKGVDAGDVQSDLVDVAKKAAHMFRCVVVITGKDDIVTDGERIVIVSNGDAMLTKVTGTGCLLSSVLGAFAGVGEDVMTSSVAALAYYGVAAEKAATQAKAPGSFQLSFLNALHETSAEEVDQYARIQGE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: FKBA_NEIMB
Sequence: MNTIFKISALTLSAALALSACGKKEAAPASASEPAAASSAQGDTSSIGSTMQQASYAMGVDIGRSLKQMKEQGAEIDLKVFTEAMQAVYDGKEIKMTEEQAQEVMMKFLQEQQAKAVEKHKADAKANKEKGEAFLKENAAKDGVKTTASGLQYKITKQGEGKQPTKDDIVTVEYEGRLIDGTVFDSSKANGGPVTFPLSQVIPGWTEGVQLLKEGGEATFYIPSNLAYREQGAGDKIGPNATLVFDVKLVKIGAPENAPAKQPAQVDIKKVN
What are the official names of this protein?
Probable FKBP-type peptidyl-prolyl cis-trans isomerase FkpA, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL372_ORYSJ
Sequence: MTKRTKKAGIVGKYGTRYGASLRKQIKKMEVSQHSKYFCEFCGKFAVKRKAVGIWGCKDCGKVKAGGAYTMNTASAVTVRSTIRRLREQTEA
What are the official names of this protein?
60S ribosomal protein L37a-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: CCD42_NEMVE
Sequence: MTVNLEEYFRTTFEDKLLVKMPEREDDHLTPATRLLEKRREMSEVEQALGAQKEEFQMKMESLQQRREELERKEYQLRESLLKFDKFLKENDSKRARALKKAQEERDMRRAKDCEIARLKEDTSGLMKGRDKVQHRLEKYIIYQQYLEKVLENAEEFQEIREIIARYDTLTATHQDLLERELKNQEKYEKEKARLIKFTEEKNNEILNYNNQLANLQTKLEKTQSVAVKWESQWTHIKNTAAKKTLLLGRIKMATHNLFMLVNRHLGQTGMVDMTDKQLDKIQVFIQDLTQITLDIKRAENAITASGANTAG
What are the official names of this protein?
Coiled-coil domain-containing protein 42 homolog.
What is the protein family that this protein belongs to?
Belongs to the CFAP73 family.
Protein: NUOA_HERA2
Sequence: MLTNYAFIGIFALAAITFPLLPLVLSAFLRPNRPTPVKLSTYECGLEAIGDIWVQFKVQYYLYALAFVIFDIETVFLYPWAVAYGQLGLFALFEMVVFLAILTIGLVYAWKKGALEWI
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRE_PROMA
Sequence: MNLPIKSNAASKEKLLTLLALKAYKNGNFTLSSGNKSNHYVNCKPVSLSGNGLLLLSNMMLENVEPDSLAVAGLTLGADPLVCGVALAATYAGRKLDALIVRKEPKGYGTASWLEGPLPPAGSVITVLEDVVTTGRSSLKAVNQLQNAGYRVNRIISIVDRQEGGAFEIKKAGLDLVSLFVLDEVYEKFKNT
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: PANC_SHEB2
Sequence: MITSAHIDDIRTQVRAWRAKGETVAFVPTMGNLHQGHITLVKEAASKCDHVVASIFVNPMQFGQNEDLDAYPRTLAADSEALTAAGAELLFTPTPAVMYPKGLEQQTYVEVPGISDVLCGASRPGHFRGVATIVCKLFNIVQPDVALFGNKDYQQLLVIKTMVEDLSLPIEIIGVDTIREDSGLAMSSRNGYLTAAEKAAAPALKQAIDAMAAGIKQGESFEQVTEQAKAKLVAAGFTPDYLEIRHAHTLEQAQNQDQALVILAAAYIGKARLIDNLRFDR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_BACC3
Sequence: MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTGEVFEVEINSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTVTMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFRGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTPLAYEHFGMEMPKV
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: Y391_PASMU
Sequence: MLEPDDIALFRGAVKGVKALKQDKFIAPRQKMSKKKSTLRDIREKEDTLFYFSDEYEPLLNEESAVRYLREGEDSHILKQLRRGDFSPELFLDLHGLTKEQAKIELASLLQACENEHVYCASVMTGYGSYILKRQIPRWLVQHPKVRALHQAPKAWGGDAAILILFEV
What are the official names of this protein?
UPF0115 protein PM0391.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: HTPG_MYCPA
Sequence: MNARVEQLEFQAEARQLLDLMVHSVYSNKDSFLRELISNASDALDKLRLEAFRNKDLDVDTSDLHIQIEVDKDARTLTIRDNGIGMTRAEVVDLIGTLAKSGTAELRQQLREAKNAQNEAASEELIGQFGIGFYSSFMVADKVELLTRKAGESEATKWESSGEGTYTIESVENAPQGTSVTLHLKPEDTEDELHDYTSEFKIKSLVKKYSDFIAWPIRMEVERRTPATEEGGEETVTREVETLNSMKALWARPKDEVSEEEYKEFYKHIAHAWDDPLEVIAMKAEGTFEYQALLFIPSHAPFDLFNRDAHTGIQLYVKRVFIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQIKAIRRRLTKKVLSTIKELQSERLDDYRTFWTQFGRVVKEGLLSDFDNQETLVQLCSFASTHSEEEATTLAQYVERMKEGQTQIFYATGETRQQILKSPHLEAFKAKGYEVLLLTDPVDEVWVGTVTEFDGKPLQSIAKGEVDLSAEGEESQAERDEQQKEFADLLAWLKDTLSDHVKEVRLSNRLTDSPACLITDAFGITPALARLYRASGQDIPVGKRILELNPKHPLVTGLRQAHQDRADDPSVAETAELLYGTALLAEGGALDDPARFAEILADRLARTL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_PHOV8
Sequence: MGARKKISAEKRKEALKTMYFAKLQNVPTSPRKMRLVADMIRGMEVNRALGVLKFSSKEASARVEKLLRSAIANWEQKNERKAESGELFVTKIYVDGGATLKRMRPAPQGRGYRIRKRSNHVTLFVDSKSTNDNQN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PTH_RICCK
Sequence: MIFVIGLGNPGKEYQYTRHNIGFIVIEKIANQYNLSFSTKKKFNCEIVESSVEKQKLIFIKPTTYMNLSGKSVISVKTYYNICSEKIFVIHDDIDLETGRIKFKTGGGNGGHNGLKSIDRVIGNNYNRIRIGVGRPQNNQDVADYVLNNFPRSEYEIVIQSIDKITNNFDLILENKLEEFKNKIG
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL332_SORC5
Sequence: MRDIIKLTCGNCGRANYHTTKNKRTMTDKFVIKKFCPTERKHTEHKEGKISKG
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SGP3_SCHGR
Sequence: MAKLLAVFLVLLIAALVCEQALACTPGSRKYDGCNWCTCSSGGAWICTLKYCPPSSGGGLTFA
What is the function of this protein?
In vitro, active against alpha-chymotrypsin.
What are the official names of this protein?
Serine protease inhibitor 3, Protease inhibitor SGPI-3, Serine protease inhibitor III.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I19 family.
What are the subcellular locations of this protein?
Secreted.
Protein: USP_ORYSI
Sequence: MASDGNGAAAVAALGISGGGGDDWAPPLRRNLPLLAPHEVKLAKLLLSEGQSHLFEHWPEPGVDDDKKRNFFDQVCRLNSSYPGGLASYIQNARKLLADSKAGKNPYDGFSPSVPSGEVLTFGDDNFVSLEEAGVKEARHAAFVLVAGGLGERLGYKGIKVALPRETTTGKCFLQHYIESILALQEASCKLVEGECNTKIPFVIMTSDDTNALTVKLLESNSYFGMEPSQVHILKQEKVACLADNDARLALDPNDKYKIQTKPHGHGDVHALLYSSGLLEQWKSTGRKWVLFFQDTNGLLFNAIPSALGVSATKGYNVNSLAVPRKAKEAIGGITKLTHVDGRTMVINVEYNQLDPLLRATGHPDGDANCETGYSPYPGNINQLILEIGPYMEELQKTHGAISEFVNPKYTDSTKTAFKSSTRLECMMQDYPKTLPPSAKVGFTVMDAWLAYAPVKNNPEDAAKVPKGNPYHSATSGEMAIYRANSLILRKAGAQIADPVIDTFNGQEVEVWPRITWIPRWGLIFKDVKAKVHSNSSVSQRSALVINGKNITIQGLSLDGTLIVNAKDEAKFNVTGHIENKGWTIQHVDHKDTSEKEEIRIRGFKFNKVEQLELNY
What is the function of this protein?
May function as the terminal enzyme of the myo-inositol oxidation (MIO) pathway.  May also play a role in the salvage pathway for synthesis of nucleotide sugars (By similarity).
What are the official names of this protein?
UDP-sugar pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the USP family.
Protein: AEP1_YEAS2
Sequence: MITTVQEISKWRNLCFIRMQSRKWYPVLKKTPLVADGRKIIKHADKVPHPEEIIHPFYQPTAIEQFTACATEYNPSLLDGKKIAPSLIKHPVSLKTILVDSKLKFDDIRGVNRWLMEFVARRQHQRNIVLTPASKSVRSFHVLHLSSTDIAKLRGLENILSEIENTNDLQSRVESVNNELQNIFDRDSKQTRLFCEDILAYLIKNYGNSTEKLILLINVTEMQLFSRLDQMKAMNIILYHILCKVEANENPPYSPTLVTALENLLAAINNRFFPGRCENSLHPIVIEQLLSYFIKTGNLNESKNFLGHLIKKGILPEATIINRYLEAIDVHFDKSTKIFDIRSKFAFIADLAPIIENYGTIDLFKFLIPMCRHFDELCSLLNIIRKSNNAKQAVDSTLPIFIKKVLTFTKDPMINSGNLSTVFNIVSPIYGQNVPSEFVEKFILSFALQGNYTMMAHMIDTYKIKLSHKYQLQIIRALKNSERNHALKNTGAVGYNKEFKKYFIEKYLNCTEREALRP
What is the function of this protein?
Required for translation of the mitochondrial OLI1 transcript encoding subunit 9 of mitochondrial ATP synthase.
What are the official names of this protein?
ATPase expression protein 1, mitochondrial, Nuclear control of ATPase messenger RNA expression protein 1.
What is the protein family that this protein belongs to?
Belongs to the AEP1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TERM_ADEB3
Sequence: MHHLKSPKNVSSVCFLQSARDCARLTGQTLHTMELFRPLRNIWNRAREYARAAISAAGISWMSRHVYRYPTLMLRNLGARQPATQNWPLYLYPPPHFLIGYQYVVRVCNDYVFETRAYSRLVYRETVRLDQQIVDWSTMANCSYTINAGAYHRFIDLENFDETLRQIQQAVLAERVVADLALIQPLRGFGRTEMADLPPQRRNVPVERFLQEQCMNLGECQDQAWGFANRIRIQQAGRRDLIILTTIRRLRCAYFNFLLSHPPPNRNNTERASPMLSLPCDCDWLEAFVQRFSDPVDAQSLRFETAASTERVVAHVIDALSLPQPAARPLTELRGGAFELRPREHGRAVTQEMRIRRGEMVQRFIESLPLPTRRRRVARPAPPSPSPSPEPVELEMPPLEGEEEEEEEELPPRSFAEEVRAAVAEVIRLLQEELTVSARNEQFFNFAVDFYEAINMLEREGNINESTIRRWVIYFFIVEHIATTLNYLHHHLRLSPVFARHVELNLGQVVMRARDEDGAVIYSRVWNEPGTNAFSQLMRRISTDLAATVHRAGRGELDEEEIERFMTDIAYRDHSGDVEEIIRQAELNDASINSVDLSFRFKVTGPVAFTQHPEIQRINRRVVQHASDLRQQLQPMPELNDPVQLPPLRPERQRPPLGPRRPL
What is the function of this protein?
Protein covalently bound to the viral DNA that acts as a primer for viral genomic replication by DNA strand displacement.  Assembles on the viral origin of replication in an initiation complex with viral polymerase, DBP, host NFIA and host POU2F1/OCT1.  During initiation, the polymerase covalently couples the first dCTP with Ser-580 of pTP.  The terminal protein stimulates the template activity over 20 fold compared to protein-free templates.  Neo-synthesized viral genomes are linked to two preterminal proteins, one for each 5' end.  These new genomes are encapsidated in the nucleus, and during capsid maturation by viral protease, preterminal protein is first cleaved into intermediary (iTP), then into mature TP.  May play a role in host nuclear matrix localization of genomic DNA.
What are the official names of this protein?
Preterminal protein, pTP, Bellett protein, Precursor terminal protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae terminal protein family.
What are the subcellular locations of this protein?
Host nucleus matrix.
Protein: MDM4_MOUSE
Sequence: MTSHSTSAQCSASDSACRISSEQISQVRPKLQLLKILHAAGAQGEVFTMKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGDLLGCQSFSVKDPSPLYDMLRKNLVTSASINTDAAQTLALAQDHTMDFPSQDRLKHGATEYSNPRKRTEEEDTHTLPTSRHKCRDSRADEDLIEHLSQDETSRLDLDFEEWDVAGLPWWFLGNLRNNCIPKSNGSTDLQTNQDIGTAIVSDTTDDLWFLNETVSEQLGVGIKVEAANSEQTSEVGKTSNKKTVEVGKDDDLEDSRSLSDDTDVELTSEDEWQCTECKKFNSPSKRYCFRCWALRKDWYSDCSKLTHSLSTSNITAIPEKKDNEGIDVPDCRRTISAPVVRPKDGYLKEEKPRFDPCNSVGFLDLAHSSESQEIISSAREQTDIFSEQKAETESMEDFQNVLKPCSLCEKRPRDGNIIHGKTSHLTTCFHCARRLKKSGASCPACKKEIQLVIKVFIA
What is the function of this protein?
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.  Inhibits degradation of MDM2.  Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.  The short isoform is a more potent inhibitor of TP53 activity than the long isoform.
What are the official names of this protein?
Protein Mdm4, Double minute 4 protein, Mdm2-like p53-binding protein, Protein Mdmx, p53-binding protein Mdm4.
What is the protein family that this protein belongs to?
Belongs to the MDM2/MDM4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XPT_BACHK
Sequence: MKVLQEKILNEGKVLSGDVLKVDAFLNHQIDPVLMQEIGKEFAKRFKEENITKIVTIESSGIAPAVMAALELGVKVIFARKRKSLTLQDNMYVANVYSFTKQETNEISLSRNHIDESDRVLIIDDFLANGQAALGLMSLVEQAGASIAGIGIVIEKAFQDGGKKLREQGIRVESLAEIASLDNNAVTFVQQETAEVK
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYI_MESFL
Sequence: MKNIYKDTLLIGQTDFDMRAGLKDKEPVIQEMWDAKKIYDQKQKLNEGKPLFMLHDGPPYANGDLHIGHALNKTLKDMIIRWKNANGYLAPFIMGWDTHGLPIETAVTKMGIDRKQTPAVEFRDMCKDYALKQVANQANQFKRLGIFSNSDVKYVTLTHDFEVSELRLFQKMYEKEMVYKALKPIYWSPSSESALAESEIEYKDVKSPTIFVAMKVVEGNAKIDTDTEIVIWTTTPWTIPSNQMAAVGENIEYNIVKANDRKFILASSLVNKVAEQIGWETFEILDTLKGPEIVGVKYAHPLYEQKINPVVIGHHVTDEAGTGIVHTAGGFGEDDYIIVKQHGIEPFAPIDDQGKFTNEIAEFDEKLVGVFYEDANKIVGMDLEAKQRLLKLKFVSHSYPHDWRTKKPVIYRCTSQWFIGLDKAKNQILANVDQITTKPEWAKKRLYQVLEDRTDWTISRQRLWGVPIVAFYDQNDKLVLNNEILAFAIDKIAELGTNAWFDKPADTFLPEAYRNKNLKKEKDILDVWFDSGSSAIALSERFKNLPLPYDLYLEGNDQYRGWFNASMINSTIYSGKSPYKKLISHGMTVDEKGNKMSKSLGNGIDPIEFANTQGADILRLWVASTDYTDDQKIGPEIIKQIGESYRKIRNTMRFILANLFDFDPSKDYQTNLTEVDRYALNNLSVVKNKASEAYDNLSYNQVYNLVVNYVTKDLSSFYLDFIKDILYIEKNDSIRRRQVQTVLYEQLWMLIDLLRPILIHTIEEVYQAMVNLNKTDSVHLLDNKKQDFIESNEFVTKWNNIMVLRDDVNKALEIAREQKIINKGFEATVKVCLKDEFKNIESTTELEKIFIVNSLSFTNDCSGLSEQKIAFVGVELKNGTKCERCWGIFDTLINNEICERCNSVVESL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_SHIB3
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFLGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDDFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEMLAPVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.