PharMolix/UniProtQA huggingface dataset:
Protein: RL5_SHIF8
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: YCAR_SALAR
Sequence: MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLENEARSLTSDESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: ALLE_ECOLI
Sequence: MGYLNNVTGYREDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
What is the function of this protein?
Involved in the anaerobic nitrogen utilization via the assimilation of allantoin.  Catalyzes the second stereospecific hydrolysis reaction (deamination) of the allantoin degradation pathway, producing S-ureidoglycolate and ammonia from S-ureidoglycine.
What are the official names of this protein?
(S)-ureidoglycine aminohydrolase, UGHY, UGlyAH.
What is the protein family that this protein belongs to?
Belongs to the UGHY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBSD_SHEPA
Sequence: MNKHALLNADMNYLAATLGHTDEVTICDAGLPIPAQVKRIDLALTHGVPSFIATVKVWLATSQIEGIVLAQEFADVSPECHQALLAEIEAEQQATGRTFSVEYISHEAFKQRTGHSRAVIRTGECTPYANVIFKTGVVF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WAXS1_SIMCH
Sequence: MEVEKELKTFSEVWISAIAAACYCRFVPAVAPHGGALRLLLLLPVVLLFIFLPLRLSSFHLGGPTALYLVWLANFKLLLFAFHLGPLSNPSLSLLHFISTTLLPIKFRDDPSNDHEKNKRTLSFEWRKVVLFVAKLVFFAGILKIYEFRKDLPHFVISVLYCFHFYLGTEITLAASAVIARATLGLDLYPQFNEPYLATSLQDFWGRRWNLMVSDILGLTTYQPVRRVLSRWVRLRWEVAGAMLVAFTVSGLMHEVFFFYLTRARPSWEVTGFFVLHGVCTAVEMVVKKAVSGKVRLRREVSGALTVGFVMVTGGWLFLPQLVRHGVDLKTIDEYPVMFNYTQKKLMGLLGW
What is the function of this protein?
Catalyzes the final step in the synthesis of long-chain linear esters (waxes).  Has activity with both saturated and monounsaturated acyl-CoA ranging from 14 to 24 carbons in length, but C20:1 acyl-CoA is the preferred substrate.
What are the official names of this protein?
Long-chain-alcohol O-fatty-acyltransferase, Wax synthase.
What is the protein family that this protein belongs to?
Belongs to the wax synthase family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein.
Protein: BIOC_SHEON
Sequence: MSMPLGVSVNSHQSASQVEHIADRFSAAAKHYQEHNCLQRLSGASLLQGFVAKGAILDIGAGPGTDFANRAMGEEMRVYALDIALGMLQQLKTIYPEHQCVCGNAEQLPFVDRSIDCIYSNLALQWCHDFSAATSEMARVLKSGGEAHLSIVAAGSLAQLSNLGLRVNGFLSLESLQAAFDDTDWQFLDVKLMPMTVYFQDLKALLYSIKGVGASVQSSVQTVTSSESDAHFGKLRGRHDWQALQQRAEQFREAQGLPLTYQIAQFRVRRQGGSV
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: CHL1_PICST
Sequence: METSICSPENRYSHPYKPYDIQIQLMDAIYDTIDNGYKIGLFESPTGTGKTLSIICSTMTWLRDYKRENVFQPMAGLDGSDTDDSDSDDEPEWVKKAYRDTIVSRSENKMVDYEMYLEKIQNEYENNIQTAGSIKSSRPPKKKRSTAKKQELHDEDFLPEDYYSDSEVKPNADKLTVLESEISQLLDKVNGRTDEIEMTNDCPVNIYFSSRTHSQLNQFAHQLALTKFQSSFKGVEERTKYLPIGSRKQLCINEKVKSFSKNDSNINDVCVDLQKSKEGCQFLPKDYLNSSLTKKLSDLSLSKIHDIEEIADLGSNMKVCPYYSVRKGVEMTEIISLPYQILLSESTRAILNLQIEDSIVVIDEAHNLMDTITSMHSVCITIGEMNSIIKALKFYLGRFLKKLNSGNRIHLMKLIKLCQLVISFIQKSEKCNNIKVGNEINTSDIYQNSTGDMLNIHILEAFLAKSKIAYKIESYMEKVAENENEQAKTSSSNPLLYKIVQFLKCLVNPSKEGKFFWDSTNGITSIKYMLLDPSSVFKDIVSKARCVILCGGTMEPMSEFKNFLFPYVEDKKIKSFSCNHIIPPDNLKVYPVSSQNNVTLEFSFDNRNNPLMIEALGASIVRICQSVPDGVVVFFPSYKYMNHILSIWKSTDVLTQIESQKKLFEEPTSASQVQTILADYANTIKEEKKGAILFSVVGGKMSEGINFADELGRAVVMVGLPYPNAYSGEIIAKRKFIESEAIARGCSMSEAQRNSQSYYENLCMRAVNQSIGRSIRHINDYSIIYLVDCRYQSSRIQNKLSSWVRKRIETRNYNMDQIMEETRDFFMCKTIARLA
What is the function of this protein?
ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity).  May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity).  Has a specific role in chromosome segregation during meiosis II (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase CHL1, Chromosome loss protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX11/CHL1 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SIM_ARATH
Sequence: MDLDLIQDLPILNFPPAIKIRANTNRDDDGGGCTTPTSSDHKIPPTTATTPPPPPQKPRPPSTPSSLGIRSCKRKLMTSLSKYEIIVNKDEIERFFSSVYNQTMASSTTTAITVAKRRRSFRSCSRR
What is the function of this protein?
Cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (PubMed:10952891, PubMed:11882294, PubMed:17098811, PubMed:17764505, PubMed:19717615, PubMed:20194967).  Inhibits the kinase activity of CYCD3-1/CDKA-1, CYCD2-1/CDKA-1 and CYCB1-1/CDKB1-1 complexes in a dose dependent manner (PubMed:26546445).  Cooperates with SMR1 and SMR2 to promote endoreplication during leaf development (PubMed:26546445).  Required for normal trichome endoreplicating cell cycles (PubMed:10952891, PubMed:11882294, PubMed:17098811, PubMed:17764505, PubMed:19717615, PubMed:20194967).  Positive regulator of effector-triggered immunity (ETI) (PubMed:25455564).
What are the official names of this protein?
Cyclin-dependent protein kinase inhibitor SIM, Protein SIAMESE.
Protein: HTPX_BURO0
Sequence: MFNWVKTAMLMAAITALFIVIGGMIGGSRGMTIALLFALGMNFFSYWFSDKMVLRMYNAQEVDENTAPQFYRMVRELATRANLPMPRVYLINEDAPNAFATGRNPEHAAVAATTGILRVLSEREMRGVMAHELAHVKHRDILISTITATMAGAISALANFAMFFGGRDENGRPANPIAGIAVALLAPIAGALIQMAISRAREFEADRGGAQISGDPQSLATALDKIHRYAAGIPFQAAEAHPATAQMMIMNPLHGGGLQNLFSTHPATEERIARLMEMARTGRFE
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
Protein: MURD2_XANOM
Sequence: MRISQFEGKAVALWGWGREGRGAYRALRAQLPTQSLTMFCNAEEVRELESLADAALHVETDASAQALGRFEIVVKSPGISPYRAEALAAAAQGTQFIGGTALWFAEHAQPDGSVPGAICVTGTKGKSTTTALLAHLLRVAGHRTALVGNIGQPLLEVLAPQPPPAYWAIELSSYQTGDVGRSGARPELAVVLNLFPEHLDWHGDEARYVRDKLSLVTEGRPRIVLLNAADPLLASLQLPDSEVLWFNHPEGWHLRGDVVYRGEQAIFDSADVPLPGVHNRRNLCAVLAALEALGLDAEALAPAALSFRPLPNRLQVLGSVDGISYVNDSISTTPYASLAALACFAQRRVALLVGGHDRGLDWHDFARHMAQQAPLEIVTMAANGPRIHALLAPLADAGRFGLHAANDLEHAMQLARDALGGQGGVVLLSPGAPSFGAYSDYVARGRHFAQLAGFDPAAISAIPGLGVH
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.  Has weak activity with D-glutamate.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanine--L-glutamate ligase, UDP-N-acetylmuramoyl-L-alanyl-L-glutamate synthetase, UDP-MurNAc-L-Ala-L-Glu synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBR1_YEAST
Sequence: MTKLRIAVQGCCHGQLNQIYKEVSRIHAKTPIDLLIILGDFQSIRDGQDFKSIAIPPKYQRLGDFISYYNNEIEAPVPTIFIGGNHESMRHLMLLPHGGYVAKNIFYMGYSNVIWFKGIRIGSLSGIWKEWDFNKQRPDWNDLENNNWKANIRNLYHVRISDIAPLFMIKHRIDIMLSHDWPNGVVYHGDTKHLLKLKPFFEQDIKEGKLGSPVTWQLLRDLRPQWWLSAHLHVRFMASIKHNKRSHEPPNKSTSKTKKNNNEIDLDLSSDEDERSGIMNCQEENEYDSKYGETRFLALDKCLPRRRWLEILEIEPDTSHASWKDENHRMFWDPEFINNLVICQKNKNLLSNKPFNSVNWIELSQSNREEGRDIDWENYAIPAYTLDIQKDEVRQTKAFISKFMT
What is the function of this protein?
Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded, thereby facilitating ribonucleotide turnover (PubMed:35459748).  It also participates in Ty1 retrovirus-like transposition via an RNA lariat intermediate in cDNA synthesis (PubMed:14716018).
What are the official names of this protein?
Lariat debranching enzyme.
What is the protein family that this protein belongs to?
Belongs to the lariat debranching enzyme family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NANE_SALAR
Sequence: MSLLEQLDKNIAASGGLIVSCQPVPGSPLDKPEIVAAMALAAEQAGAVAVRIEGIDNLRVARSLVSVPIIGIIKRDLDESPVRITPFLDDVDALAQAGANIIAIDGTARQRPVTVEALLARIHHHHLLAMADCSSVDDGLACQRLGADIIGTTMSGYTTPDTPEEPDLPLVKALHDAGCRVIAEGRYNSPELAAKAIRYGAWAVTVGSAITRLEYICGWYNDALKKAAS
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: TSAD_CHLT3
Sequence: MNILGIETSCDETSAAVLKNGLVASNIISSQLCHSEFGGVVPELASREHDRMVVTVVEAALNAANIKKTELDFIAATAGPGLIGAVLVGLSFGQALGFSLGKPFIPINHIDAHIFSSFINDGTQHTFPAFPFVSLTVSGGHTMLCLVHDDLRIEPLGSTIDDAAGEAFDKTGKMLGLNYPAGPVIDKLAQTGDPNFHQFPQALTAQSKTGNDYKANLDFSFSGLKTSVLRYLSGQKPEFIQAHLNDICASIQEAITSVLVRKTILAAEQSGVRTISVTGGVSANSELRRKFEAASKAHGFSLHIPKPVYSTDNAAMIATLAHLKAERGLIEPCAYNAPAFAGYEKMKVFRAR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRCA_STAAR
Sequence: MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLLNTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: SPAM_SHISO
Sequence: MEALDKRIIYFLQLENDLEPVGAQSVSQLFNTRRKIAIVKKHIIQYQSERILLKGRIEEIQKDIDEANASKRKLLHKESKICKRIGLIKRNNFAKQLILDELSQEDMKYGIR
What is the function of this protein?
Required for surface presentation of invasion plasmid antigens.  Could play a role in preserving the translocation competence of the ipa antigens.  Required for invasion (By similarity).
What are the official names of this protein?
Surface presentation of antigens protein SpaM, Spa13 protein.
What is the protein family that this protein belongs to?
Belongs to the SpaM family.
Protein: RRF_PSEFS
Sequence: MINEIKKDAQARMQKSLESLSHAFGQIRTGKAHPSILGSVMVPYYGSDTPISSVANITVKDSRTLQVVAFERNMLGAVDKAIQSAGLNLNPTNLGELLLISMPALTEETRKGFTKQARSAAEDARVAVRNIRRDALGDLKKLVKDKEISEDEERRATADIDKLTKDAEAQITKATEEKEKDLMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_BORPE
Sequence: MSEAAHSGAAPADLVELGRIASAYGVKGWVKVQPHSAQAEVLRTVSHWWLTRPAPQAARDVVASVPRAYQVLQARVHGGAVVAQLAGIDDRDQAEALRGCFVQAARSAFPAPADDEYYWVDLIGCALYSDADGEPRLLGVVDEVFDNGAHAVLKVLRQQIQPGQPGPVPLLDPKGRPLEELVPFVRAHIRHVDLAARRIDSDWPLDY
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BIFLD
Sequence: MVDIIDKALRMGEGHQLKKLENVAKAVNALEDEISALSDEDLKAQTPKFKQEIENGKSLDEIMPEAFATVREVSKRTLGQRHFDVQLMGGAALHWGNIAEMKTGEGKTLVATLPTYLNALEGKGVHVVTVNDYLASYQSELMGRIYRFLGMNVGCIITEQKPPERRKQYNADITYGTNNEFGFDYLRDNMAWEKADLVQRGHHYAIVDEVDSILIDEARTPLIISGPAEGDVTRWYRQFAKLVLKLTRDEDYDVDEKKKVVGILDPGITKVEDFLGIDNLYEPANTALIGYLNNAIKAKELFLRDKDYVVTQGEVLIVDEHTGRILPGRRYNEGLHQAIEAKEGVEVKAENQTFATITLQNYFRMYDKLAGMTGTAETEAAEFMNTYKLGVLPIKTNKPMIRKDQDDLIYRTKKEKLAAIVKDVAKRHAKGQPVLLGTASVESSEVVSTLLDVAKIPHQVLNAKQHEKEAAVVAVAGRKGAVTVATNMAGRGTDIMLGGNVEFLADAKLKSEGYSPEDTPEEYEKRWPGTLNEIKAQVKDEHEEVKELGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLEDDLMRLFNTQLVAQVMAKGMEEGQPIEAKSVTKGVRTAQKAVESRNYEIRKNVLKYDDVMNKQRTVIYSERQAVLKGEDIHKDILRFISDTVESYIKGANKGSEKPKDWDWEGLFKALNTVIPTKVDEDEVRKIVGGLKGAKAVEAVRDLIVEDARQQYGEMEETIGETGLRDLERRVVLAVLDRKWREHLYEMDYLKDGIGLRGMGQRDPLVEYQREGYQMYNSMIEAIKEETVQLLFHIDIKQVATTDEAVDEVEETAESADTIAVASGPDENGESVVEAAEGEVEEEDEDTDAKQAIAESAAASGAGESTLPVAGPAPISHAEGKVPVSKRPKSEELKTPWADGRTFPGTGKNAPCPCGSGRKYKMCHGQNEK
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: EFTS_SALG2
Sequence: MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNVAFILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVASLEGDVLGSYQHGARIGVLVAAKGADEELVKQLAMHVAASRPEFVKPEDVSADVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKSVGQLLKEHNADVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBX8_MOUSE
Sequence: MELSAVGERVFAAEALLKRRIRKGRMEYLVKWKGWSQKYSTWEPEENILDARLLAAFEEREREMELYGPKKRGPKPKTFLLKAQAKAKAKTYEFRSDSTRGIRIPYPGRSPQDLASTSRAREGLRNTGLPPPGSSTSTCRADPPRDRDRERDRGTSRVDDKPSSPGDSSKKRGPKPRKEPLDPSQRPLGEPSAGLGEYLKGRKLDETSSGTGKFPAGHSVIQLARRQDSDLVQYGVTSPSSAEASSKLAVDTFPARVIKHRAAFLEAKGQGALDPGGARVRHSSGTPASVGSLYRDMGAQGGRPSLIARIPVARILGDPEEESWSPSLTNLEKVVVTDVTSNFLTVTIKESNTDQGFFKEKR
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
What are the official names of this protein?
Chromobox protein homolog 8, Polycomb 3 homolog, Pc3, mPc3.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to the inactivated X chromosome in females.
Protein: SYL_BORA1
Sequence: MQERYQPNLVEAAAQQDWQARDAYLVHESAKNADGSEKPKFYACSMLPYPSGKLHMGHVRNYTINDMMARQLRMRGYNVLMPMGWDAFGMPAENAAIKSKVPPAKWTYDNIAYMKKQMKAMGLAIDWSREMCACDPAYYKWNQWLFLKMLEKGIAYRKTQVVNWDPVDQTVLANEQVIDGRGWRSGAPVEKREIPGYYLRITDYADELLDQVKNGLPGWPERVRVMQENWIGKSEGVRLAFPHDIKDENGQLIQDGKLFVFTTRADTVMGVTFCAVAPEHPLATLAARNNPALATFIEQCKLGGTTEAEIATREKEGIPTGLSVKHPLTGQAVDLWVGNYVLMSYGDGAVMGVPAHDERDFAFARKYGLTIRQVIAQEGKTYSDQAWQEWYGDKQTGRTINSGKYDGLSTAEAVDAIAADLNALGLGEKQTTYRLRDWGISRQRYWGTPIPIIHCQDCGPVPVPEQDLPVVLPDDLIPDGSGNPLAKNEAFLSCSCPACGKPARRETDTMDTFVDSSWYFMRYTSPGNDQAMVDKRNDYWMPMDQYIGGIEHAVLHLLYARFWTKVMRDLGMLKFDEPFTRLLCQGMVLNHIYSRRTPQGGIEYFWPEEVENIYDAKGAIVGARLKSDGSEITYGGVGTMSKSKNNGVDPQSLIDTLGADTARLFVMFASPPEQTLEWSDSGVDGANRFLRRLWALAYDRRAAVARGLASGYAWQDAPAPVKDLRRELYGLLKQAEYDYQRIQYNTVVSASMKMLNAIDNAQLPEGPAADAAIAEGLGLLLRVLYPVVPHVTWHIWRDLGYAAELGDLLDAPWPHVDEAALIADEIELMLQVNGKLRGAIRVAAQAAKEDIEKIAVAQEEVARFLEGRPPKRVIVVPGKLVNVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPA_PSEPF
Sequence: MAQQYQPGQRWISDSEAELGLGTVLAQDGRLLTVLYPATGETRQYALRNAPLTRVRFSPGDSITHFEGWKMTVQQVDDVDGLMVYHGLNAQNEAVTLPETQLSNFIQFRLASDRLFAGQIDPLAWFSLRYHTLEHTSRQLQSALWGLGGVRAQPIAHQLHIAREVADRIAPRVLLADEVGLGKTIEAGLVIHRQLLSGRANRVLILVPENLQHQWLVEMRRRFNLQVALFDEERFIESDATNPFEDTQLALVALEWLVDDEKAQDALFAAGWDLMVVDEAHHLVWHEDKVSPEYSLVEQLAEVIPGVLLLTATPEQLGQDSHFARLRLLDPNRFHDLAAFRAESENYRPVAEAVQELLDKGRLSPAAHKTIHGFLGNEGEALLTAVNDGDTEASARLVRELLDRHGTGRVLFRNTRAAVQGFPERKLHPYPLPCPDEYLELPLGEHAELYPEVSFQAQPDASEEERWWKFDPRVEWLIDQLKMLKRTKVLVICAHAETAMDLEDALRVRSGIPATVFHEGMNILERDRAAAYFADEEFGAQVLICSEIGSEGRNFQFAHHLVLFDLPSHPDLLEQRIGRLDRIGQKHIIELHVPYLETSPQERLFQWYHEALNAFLNTCPTGNALQHQFGPRLLPLLEEADDGEWQALIDEARTERERLEAELHTGRDRLLELNSGGAGEGEALVEAILEQDDQFALPIYMETLFDAFGIDSEDHSENALILKPSEKMLDASFPLGDDEGVTITYDRNQALSREDMQFITWEHPMVQGGMDLVLSGSMGNTAVALIKNKALKPGTVLLELLYVSEVVAPRSLQLGRYLPPAALRCLLDANGNDLSSRVAFETLNDQLESVPRASANKFIQAQRDQLTPRINAGEDKVTPRHAERVAEARRRLAADTDEELARLTALQAVNPTVRDSELDALRKQREQGLAMLDKAALRLEAIRVLVAG
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: TNP2_ECOLX
Sequence: MPRRSILSAAERESLLALPDSKDDLIRHYTFNDTDLSIIRQRRGPANRLGFAVQLCYLRFPGVILGVDELPFPPLLKPVADQPKVGVESWNEYGQREQTRREHLSELQTVFGFRPFTMSHYRQAVQMLTELAMQTDKGIVLASALIGHLRRQSVILPALNAVERASAEAITRANRRIYDALAEPLADAHRRRLDDLLKRRDNGKTTWLAWLRQSPAKPNSRHMLEHIERLKAWQALDLPTGIERLVHQNRLLKIAREGGQMTPADLAKFEPQRRYATLVALATEGMATVTDEIIDLHDRILGKLFNAAKNKHQQQFQASGKAINAKVRLYGRIGQALIDAKQSGRDAFAAIEAVMSWDSFAESVTEAQKLAQPGGFGFLHRIGESYATLRRYAPEFLAVLKLRAAPAAKNVLDAIEVLRGMNTDNARKLPADAPTGFIKPRWQKLVMTDAGIDRAYYELCALSELKNSLRSGDIWVQGSRQFKDFEDYLVPPEKFTSLKQSSELPLAVATGCEQYLHERLTLLEAQLATVNRMAAANDLPDAIITESGLKITPLDAAVPDTAQALIDQTAMVLPHVKITELLLEVDEWTGFTRHFTHLKSGDLAKDKNLLLTTILADAINLGLTKMAESCPGTTYAKLAWLQAWHTRDETYSTALAELVNAQFRHPFAGHWGDGTTSSSDEQNFRTASKAKSTGHINPKYGSSPGRTFYTHISDQYAPFHTKVVNVGLRDSTYVLDDLLYHESDLRIEEHYTDTAGFTDHVFALMHLLGFRFAPRIRDLGDTKLYIPKGDAAYDALKPMIGGTLNIKHVRAHWDEILRLATSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRVERTLFILDWLQGVELRRRVHAGLNKGEARNALARAVFFNRLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYLERAAHALRGNGHAVDDSLLQYLSPLGWEHINLTGDYLWRSSAKIGAGKFRPLRPLQPA
What is the function of this protein?
Required for transposition of transposon Tn21.
What are the official names of this protein?
Transposase for transposon Tn21.
What is the protein family that this protein belongs to?
Belongs to the transposase 7 family.
Protein: CDR_STAAM
Sequence: MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCALPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVIGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEIDAINGNEITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFASVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGADKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK
What is the function of this protein?
Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide.
What are the official names of this protein?
Coenzyme A disulfide reductase, CoA-disulfide reductase, CoADR.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family.
Protein: CALM_CANAX
Sequence: MAEKLSEQQIAEFKEAFSLFDKDSDGKITTKELGTVMRSLGQNPSESELTDMINEVDVNSDGSIDFPEFLTMMARKMKDTDSEAEIAEAFKVFDRNGDGKISAAELRHLLTSIGEKLSDADVDQMIKEADTNNDGEIDIQEFTSLLAAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.