PharMolix/UniProtQA huggingface dataset:
Protein: H2B_DROTE
Sequence: MPPKTSGKAAKKAGKAQKNITKTDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ASD_METJA
Sequence: MGKYKKFFAIAVCSLLLFTVYFYRDPDRVITKGNNIILSPADGTVEYIKFYENGNPEVFKDGNCYVLNVSRYFPNGCYVVGIFMSPLDVHVNRAPIGGRIVYIKHIDGSFYPAFLEGVEKINERNIVIIKNGSEYVGVVQIAGFVARRCWLSIKEGECINMGQKIGMIKLGSQTAVIIPANYNITVKVGERVYAGQTIIAVKRTDN
What is the function of this protein?
Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer).
What are the official names of this protein?
Putative archaetidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ATPD1_PHOPR
Sequence: MSDMTTIARPYAKAAFDFAVENGELAQWAEMLTFASEVVKNEAMQDILRSGFSADKLTEIIVSVCDEQLNEFGQNLLKVMAENGRLTMVPAVSDEFLFLKNEHEKTIEADVISAVVLEDSQLVAISQKLEQRLERKVKLNCSVDETLIAGVVIRAGDLVIDNSVRGKLNRLSDTLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta 1, ATP synthase F(1) sector subunit delta 1, F-type ATPase subunit delta 1, F-ATPase subunit delta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: USPB_ECOLU
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUVA_CUPPJ
Sequence: MIGRIAGTLIEKNPPHLLVDCHGVGYEIDVPMSTFYNLPATGQPVTLLTQLIVREDAHLLYGFGSAAERNTFRELIKITGIGARMALAVLSGMSVSELAQAITLQEAGRLTRVPGIGKKTAERLMLELKGKLGAELGHAPGAAPVHDSAVDILNALLALGYSEKEAATAIKQVPAGTGVSDGIKLALKALSKA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MUTL_BORT9
Sequence: MNKIKFLDRSLVQKIAAGEAIDRPCSILRELLDNSIDSGADKIEVFLEEGGIRRILITDNGSGISKEDLKICYLPHTTSKINEEKDLEKIQTLGFRGEALSSIAICSNLTITSSTTGEDSYQIEVENGTEKYFKKQSAINGTIVDVTNLFHNFPARKRFLKKDSIETKMCLKVFEEKAVTHPGIDFKLSLNNELRKVYFKESLINRVQSVYGEIIENNKFGKIETEYENVQMKIFFAPPNFSRKDRRNIKIFLNRRPVEEHNLSEAIIDGHSRILTNRNFPICYLFLEIDPRYVDFNIHPQKKEVRFFNLPFLPKQVSSNINEFFDRERKEILQDYHNIIIKRQITNDAHLLHPEDDPTNSDFQTYEIIQNESLILDKPQNNKITNIIEDKVKFESQNPIQKDKPSFKSYIQNILLETSTIANDFQKPIAKHEFKYRGQLFSEFLIVEKDNEVFFIDQHALHEKIIYQTLINSEKITQKLLIPIEFQVDCEDTDKILASELEEYKKLDIIVTKIKEQTYQLESIPNICNKYENVIIQFFKTRKSKTIDSLETDLYATIACRQAVKCNDTISSEFSQFLINEFFNLKLKYCPHGRKIYHKISKFELEKSVNRK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: GLYA_DEIDV
Sequence: MTTAESPATRDTAIFDLIRQEAERQRSGLELIASENFTSAAVREAQGSVLTNKYAEGYPGKRWYGGCEIVDQVEQLAIDRVKELFGAAWANVQPHSGSSANLAVYNALIEPGDTVLGMDLSHGGHLTHGNPVNFSGLRYKIVGYQVNPETELIDMNVVRRLAHEHRPKMIIAGASAYSRSIDFAAFREIADEVGAILFADIAHIAGLIAAGEHPNALPHAHVVASTTHKTLRGPRGGIILSNDLELGAKIDRAVFPGYQGGPLEHVIAAKAVAFGEALRPEFKDYARQVIRNAQALAIAFQQRGYRVVSGGTDNHLLVLDLRAQGLNGTKATKRLDANHITISKSTLPYDTEKILHGGGIRLGTPAVTTRGMTEEHMQVIADLIDRALKGEDVQAEVHDFAGRFPLP
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR9_DELRA
Sequence: LPEQDFMRF
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
FMRFamide-like neuropeptide LPEQDFMRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYT_MYCVP
Sequence: MSAPARPAPAAPIRVAAGTTAGQAVRDAGLPSRGAPDAVVVVQDPDGRLRDLSWVPDADVDVIPVTADTEDGRSVIRHSAAHVLAQAVQALFPDAKLGIGPPITDGFYYDFEVAEPFTPEDLEALEKRMRQIVKDGQLFSRRVFESKDEAREELANEPYKLELIDDKSGDLESSDEIMEIGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTRYIPAFKLTRSSAAYWRGDQNNASLQRIYGTAWESQEALDRHLELIEEAQKRDHRKLGVELDLFSFPDELGSGLPVFHPKGGVVRRELEEYSRRKHIEAGYEFVNTPHITKEHLYITSGHLEWYADGMFPAMHIDAEYNDDGTVRKPGQDYYLKPMNCPMHHLIYRSRGRSYRELPLRLFEFGSVYRYEKSGVVHGLTRVRGMTQDDAHIYCTREEMRDELARLLQFVLDLLADYGLDDFYLELSTKDPDKFVGSDDMWEEATETLREVAESSGLHLVPDPGGAAFYGPKISVQVRDALGRNWQMSTIQLDFNMPDRFELEYTAADGTRKRPVLIHRALFGSIERFFGVLTEHYAGAFPAWLAPVQVVGIPVADDHIRYLDGLVAQLRALGIRAEVDTSDDRMAKKIVNHTNQKVPFMLLAGDRDVEAEAVSFRFGDRTQVNGVPREQAVAAIVDWVTRRENATPTAELVEISAETGEG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPUCB_LISM4
Sequence: MDAIVTFFQENGHNLLVQTWQHLFISLSAVILGIAVAVPTGILLTRSPKVANFVIGVVSVLQTVPSLAILAFIIPFLGVGTLPAIIALFIYALLPILRNTFIGVRGVDKNLIESGRGMGMTNWQLIVNVEIPNSISVIMAGIRLSAVYVIAWATLASYIGAGGLGDFIFNGLNLYRPDLILGGAIPVTILALVVEFALGKLEYRLTPKAIREAREGGE
What is the function of this protein?
Part of the ABC transporter complex OpuCABCD involved in carnitine uptake.  Probably responsible for the translocation of the substrate across the membrane.  Involved, with BetL and GbuABC, in osmoprotection and cryoprotection of Listeria.  Can also mediate weak glycine betaine transport.
What are the official names of this protein?
Carnitine transport permease protein OpuCB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTPG_SODGM
Sequence: MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSQPDLYEGDGELRVRLSCDKEKRTLTFSDNGIGMRREEVIDNLGTIAKSGTKAFLESMGSDQLKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGAKPDGGVFWESAGEGDYTIADITKPERGTEITLHLREGEDDFLDDWRLKSVIGKYSDHIVLPVEIETRSKSEEEGSDEEVVTWEKINKAQALWTRNKADISDDEYKEFYKHLSHDFSEPLSWSHNRVEGKQEYTSLLYIPAKAPWDMWNREHKHGLKLYVQRVFIMDDAEQFMPNYLRFVKGLIDSNDLPLNVSREILQDSRVTQNLKGALTKRALSMLEKLAKDDAQQYQSFWQEFGLVLKEGAGEDPTNGEAVAKLLRFASTHGDSPAQTVSLEEYVGRMVEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLFSDRIDEWMMSYLTEFDGKAFQSVSKADPSLDKLADEEDEEQKEVEKALEPFVERVKTYLGERVKEVRLTHRLTDTPAVVTTDADDMTTQMAKLFAAAGQAAPEIKYIFELNPDHALVKRTANLGDDGAFGDWVELLLDQALLAERGTLDDPNQFIRRMNQLLNA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF137_ASFM2
Sequence: MEAALTKLDQEEKRALQAYYRCAWEETKNIINDFLEIPEERCTYKLNSYTKKMELLFTPEFHTAWQEVFECREFIINFLRLITGHRVVLKGPAIVFTKETKNLGIPSTINVDFQANIENMDDLQKGNLIGKMNIKEN
What is the function of this protein?
Plays a role in the inhibition of the host innate immune response.  Mechanistically, promotes the autophagy-mediated lysosomal degradation of host TBK1 and affects IRF3 nuclear translocation to block type I IFN production.
What are the official names of this protein?
Structural protein A137R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus A137R family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: ENGB_VIBC3
Sequence: MSVKIHYQNTHFITSAPDIRHLPEDEGIEIAFAGRSNTGKSSSLNRLTNQKNLAKTSKTPGRTQLINLFKVADGCHIVDLPGYGFAQVPLEMKLKWQRALGEYLQKRQSLKGLVVLMDIRHPMKDLDQQLIIWAVECGIPVQVMLTKADKLKSGARKAQVLKVREEAKTFGGDVAVDAFSSLSGIGVDTLRAKLDEWYAPMLAALAEQEEGEQPESSTDQ
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RS7_SODGM
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAEAIVYTALETLAQRSGKGHLEAFEVALDNVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMADANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RL21_BRUME
Sequence: MFAVIKTGGKQYRVAANDLIKVEKVAGEAGDIVEFAEVLMVGSTIGAPTVAGALVTAEVVEQGRGRKVIAFKKRRRQNSKRTRGHRQELTTIRISEILTDGAKPSKKAAEKKAPKADAAEGEAAKPKKAAPKKAAAKAESAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RPPB_SYNY3
Sequence: MNTRRLFARSRLQLAFWYALVMGGILTLLGLGVYRAIVQANWMALEREVESIAGTLHDSLEPMLPSNASPTGVLQKMLPDLCLVNQPCQVNPTLIERHTLGISDRSLYYIRLFDYQGNLLAFSPNQPASLSSIFNQETWQTIHPPTGDRYRQFTTILHSAGNTDKSSWGYLQIGRSLAAFDAENKRILWILGLSFPIALGLVAFSSWGLAGLAMRPIYQSYQQQQQFTANAAHELRSPLASLLATVEAVLRIDSSHSPEINTMLHTVERQGRRLSQLITDLLLLSRLEQETTAEDWRLCCLNDLVSDLTEEFLELAIAAHIDLSSDLSSGEVYAWGNESQLYRLVSNLIANAIQYTTAGGRVDITLTSHEQMAIITVQDTGIGIAPDQQEHIFERFYRVNRDRSRKTGGTGLGLAIAQVITVKHRGSLTVESALGKGSLFTIQLPIFSVPIVHS
What is the function of this protein?
Member of two-component regulatory system RppA/RppB, involved in the establishment of the appropriate stoichiometry between the 2 photosystems.  It senses changes in the plastoquinone (PQ) redox poise (PubMed:10894737).  Another group shows this two-component pair, renamed NrsR/NrsS, controls the nickel-dependent expression of the nrsBACD operon; they suggest the photosystem-related activities seen earlier are due to the expression of NrsS (RppB) in the absence of its natural substrate NrsR (RppA) (PubMed:11849552).
What are the official names of this protein?
Sensor histidine kinase RppB, Sensor histidine kinase of nickel resistance operon NrsS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ASNO_STRCO
Sequence: MAANAAGPASRYDVTLDQSDAELVEEIAWKLATQATGRPDDAEWVEAARNAWHAWPATLRRDLAGFRRDSGPDGAIVLRGLPVDSMGLPPTPRVNGSVQREASLGAAVLLMTACGLGDPGAFLPEKNGALVQDVVPVPGMEEFQGNAGSTLLTFHNENAFHEHRPDFVMLLCLRADPTGRAGLRTACVRRVLPLLSDSTVDALWAPEFRTAPPPSFQLSGPEEAPAPVLLGDRSDPDLRVDLAATEPVTERAAEALRELQAHFDATAVTHRLLPGELAIVDNRVTVHGRTEFTPRYDGTDRWLQRTFVLTDLRRSRAMRPADGYVLGAAPQPA
What is the function of this protein?
Catalyzes the 3-hydroxylation of L-asparagine to (2S,3S)-3-hydroxyasparagine.  The 3-hydroxylated asparagine produced is incorporated at position 9 during the biosynthesis of the non-ribosomally synthesized calcium-dependent antibiotic (CDA), a 11-residue acidic lipopeptide lactone.  Is able to hydroxylate only free L-asparagine, since it hydroxylates neither a CDA analog with unmodified Asn at position 9 nor a peptidyl-carrier-protein (PCP)-bound asparagine.  Is not active toward D-asparagine.
What are the official names of this protein?
L-asparagine oxygenase, L-asparagine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the clavaminate synthase family.
Protein: RS13_NITOC
Sequence: MARIAGINIPVHKHTVIALSSIYGIGLSRARKICGAVGVPSDKKIRDLSDNELEGLRAEVAKYPVEGDLRREISMDIKRLMDLGCYRGIRHRRGLPVRGQRTQTNARTRKGPRRLARK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: EFP_TRIEI
Sequence: MISSNDFRPGVTIELDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVERTFRAGETVPQATLDKRAMQHTYKDSDQFVFMDMETYEETNLSSEQIGERVKYLNEGMEVNVIMWGEQVIEVELPNSVVLEVIETDPGVKGDTATGGSKPATVETGAQIMVPLFISKGERIKIDTRNDSYLGRE
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_DESVH
Sequence: MAVKLRLTRMGNKKRAFYRIVAVNSETRRDGRPLEYIGFYNPMVDPAEVKIDAEKVQKWLALGAEPTDTVRNLIKKQQA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SYFA_SALPK
Sequence: MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCA_RHILO
Sequence: METKFGVHSEVGQLRKVMVCAPGRAHQRLTPSNCDALLFDDVLWVDNAKRDHFDFMTKMRDRGVEVVEMHNLLAETVAVPEGKKWILDNQVVPNQIGLGLVDEVRSYLEGLSNRDLAETLIGGLSTHEFPESIGGEQLELIRDAAGVNEYLLPPLPNTLYTRDTTCWIYGGVTQNPLYWPARHEETILTTSIYKFHPDFAGKVNVWWGDPTKDWGLATLEGGDVMPIGKGNVLIGMSERTSRQAISQLAATLFEKGAAERVIVAAMPKLRAAMHLDTVFTFADRDCVLLYPDIVNGIEAFSYRPDGKGGVELHKDKGTFVETVRDALGLKKMRVVETGGNAYMRERTQWDSGANLVCASPGVVYAYDRNTYTNTLLRKEGIEVITIIGAELGRGRGGGHCMTCPIIRDAVDY
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAP1_LATCU
Sequence: TPVVNPPFLQQT
What is the function of this protein?
Has antibacterial activity against the Gram-positive bacteria L. monocytogenes, L. lactis subsp lactis and L. curvatus H28, but not against the Gram-positive bacteria L. curvatus CWBI-B28, L. brevis and L. plantarum or the Gram-negative bacteria E. coli and Pseudomonas sp 55.  Has no antifungal activity against S. cerevisiae, Penicillium sp BKS-TAN2 or A. niger.
What are the official names of this protein?
Bioactive peptide 1, BAP1.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU3_BURPS
Sequence: MKIAVLPGDGIGPEIVNEAVKVLNALDEKFELEQAPVGGAGYEASGHPLPDATLALAKEADAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPELVAGLDILIVRELNGDIYFGQPRGVRAAPDGPFAGAREGFDTMRYSEPEVRRIAHVAFQAARKRAKKLLSVDKSNVLETSQFWRDVMIDVSKEYADVELSHMYVDNAAMQLAKAPKQFDVIVTGNMFGDILSDEASMLTGSIGMLPSASLDQRNKGLYEPSHGSAPDIAGKGIANPLATILSAAMLLRYSLNRAEQADRIERAVKAVLEQGYRTGDIATPGCKQVGTAAMGDAVVAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_STRM5
Sequence: MTDDRIIGAGATREDDAADASIRPKRLADYLGQVPVREQMEIYIQAAKGRGDALDHVLIFGPPGLGKTTLSHVIANELGVALRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGEGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRLEFYSVEELTRIVRRSAAILAIDCTADGAGEIARRARGTPRIANRLLRRVRDYAQVKAGGHIDEAVAQAAMKMLKVDPEGFDELDRRLLKTMVDYFDGGPVGIESLAAALSEERGTLEDVVEPYLIQQGFLVRTARGRMATHKAYRHMGLKPKNPPQDLFAEVPDVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: IF1_MESFL
Sequence: MAKEAEMEFEGTVVEVLPNAKFKVQLENDIVIDAHVSGKIRMHYIRILPGDKVTVVISPYDMTRGRITYRKIAKKAEV
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_CITBB
Sequence: MEYLLSIDQGTTSSRATLYAASGESLATASRPLAQHYPNPGWVEHDPQEIWEGQLACITEAVAKAGIAPSQIAGVGITNQRETTVVWERETGLPLHRAIVWQDRRTAELTESLKEQGLEAMVRERTGLLLDPYFSASKLCWLLDRVDGLRQRAERGEVCFGTVDSWLMFKLSGGKSHLTDISNASRTMLFNINTLEWDEELLRLFRIPRGMLPEVRGSAAGFGHTSGEVAGAEIHIAGVAGDQQAALFGQGCFAPGMAKATFGTGAFVVMNSGARPGVGDGALSTIAWQLPGEAVQYALEGSIFIAGAAVQWLQEGLGLIGNAREVEVLAASVPDSGGVYFVPALSGLGTPYWDPYARGVVAGLTRGSTKAHLARAALEAIAFQTLDAIRAMEQASGIALKELRVDGGAAANNLLLQIQADLLGVPVLRPRCTESTSLGAAFLAGIGAGVLDTSAIAAQWALDRRFEPQMERERREELHRGWQKCVRLSLGWEKN
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.