PharMolix/UniProtQA huggingface dataset:
Protein: RPOA_MYCA1
Sequence: MLISQRPTLSEEVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTAIILNLKSLVVSSEEDEPVTMYLRKQGPGEVTAGDIVPPAGVTVHNPELHIATLNDKGKLEVELVVERGRGYVPAVQNRASGAEIGRIPVDSIYSPVLKVTYKVDATRVEQRTDFDKLILDVETKSSITPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHIASFALPIDDLDLTVRSYNCLKREGVHTVGELVSRTESDLLDIRNFGQKSIDEVKVKLHQLGLSLKDSPPSFDPSQVAGYDVATGTWSTEAAYDDQDYAETEQL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PHL5_ARATH
Sequence: MMDNINFEFSNASQGSRLQLQQQPPQPFNLQDLNMIQYNQPSSPWTTETFSGLTPYDCTANQSFPVQCSSSKPYPSSFHPYHHQSSDSPSLDQSVSMIPMQPLPDQYMKPLYQRSCSNDFAATNASSASYSLSFEASHDPQELCRRTYSNSNVTHLNFTSSQHQPKQSHPRFSSPPSFSIHGGSMAPNCVNKTRIRWTQDLHEKFVECVNRLGGADKATPKAILKRMDSDGLTIFHVKSHLQKYRIAKYMPESQEGKFEKRACAKELSQLDTRTGVQIKEALQLQLDVQRHLHEQLEIQRNLQLRIEEQGKQLKMMMEQQQKNKESLLKKLPDAEASLSLLDPHIHSPPSPFLVHDAEALMLTSYEDTQLQSTKS
What are the official names of this protein?
Myb family transcription factor PHL5, Protein PHR1-LIKE 5.
What is the protein family that this protein belongs to?
Belongs to the MYB-CC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL1_STRSY
Sequence: MAKKSKNLLAALEKIDSTKLYSVEEAVALAKETNFAKFDASVEVAYNLNIDVRKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVAKINGGWLDFDVVIATPDMMAVVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADKAGIVQALIGKVSFDADKLVENFKAFHDVMAKAKPATAKGTYMTSVFITTTQGVGIKVDPNSL
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: VP5_BTV11
Sequence: MGKIIKSLSRFGKKVGNALTSNTAKKIYSTIGKAAERFAESEIGAATIDGLVQGSVHSIITGESYGESVKQAVLLNVLGTGEELPDPLSPGERGIQTKIKELEDEQRNELVRLKYNKEITKEFGKELEEVYDFMNGEAKEEEVVQEQYSMLCKAVDSYEKILKAEDSKMAMLARALQREASERSQDEIKMVKEYRQKIDALKNAIEIERDGMQEEAIQEIAGMTADVLEAASEEVPLIGAGMATAVATGRAIEGAYKLKKVINALSGIDLSHMRSPKIEPTIIATTLEHRFKEIPDEQLAVSVLNKKTAVTDNCNEIAHIKQEILPKFKQIMDEEKEIEGIEDKVIHPRVMMRFKIPRTQQPQIHIYAAPWDSDDVFFFHCVSHHHRNESFFLGFDLGIDVVHFEDLTSHWHALGLAQEASGRTLTEAYREFLNLSISSTYSSAIHARRMIRSRAVHPIFLGSMHYDITYEALKNNAQRIVYDEELQMHILRGPLHFQRRAILGALKFGVKILGDKIDVPLFLRNA
What is the function of this protein?
VP5 protein is one of the two proteins (with VP2) which constitute the virus particle outer capsid.  Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm.  Permeabilization activity is probably negatively regulated by VP2 and is triggered by endosomal degradation of VP2 and exposure to low pH (By similarity).
What are the official names of this protein?
Outer capsid protein VP5.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP5 family.
What are the subcellular locations of this protein?
Virion.
Protein: PKHH3_RAT
Sequence: MPLPGGLWWLLCCRRGFTLLHRDYGDGELSGDGDEDEDDETFELRSPSPAGGGRGSLDVTLTQPTRNGPITDRLQSWEETWSLIPDKGLPEDDPDVIVKGWLYREPRGGGARPWLLPRRAWFVLTRDSLDQFSSSGKGARRLGSLVLTSLCSVTGPERRPKETGLWSVTVSGRKHSIRLCSPRQAEAERWGVALREVIASKAPLETPTQLLLRDIQESGGDPEAVALIYRRNPILRHTSSALYAPLLPLPYEVSAPGPGYAPLREEAVRLFLALQALEGARRPGPLMQGVLQTCRDLPALQDELFLQLAKQTSGPAGPPGLPATQDPAALRYWQLLTCMSCTFRPGGAVRGHLLGHLERTEQALPDSELAEYARFIRKALGRTRGRELVPSLAEISALSRRQELLCTVHCPGAGACPVSIDSHTTAGEVARELVGRLGLARSRNAFALYEQRGAQERALAGGTLVADVLTSLTSEEVGLEDSPDSGWRLCLRLHGPLHPEGLSPEGHELPFLFEQAHALLLRGRPPPPDDTLRALAALRLQSLHRDFSPRGPLPLLDRLMPPPAPPREQPSRPARRPPPSAALLAGALWSPGLAKRRAERARRIGTGRSTESTAQVGGGGGGSTTAAVLGGWKRLRGMGQAEAMAAYLALAAQCPGFGAARYDVLELSTEPGGGAPQKLCLGLGAKAMSLSRPGESEPIHSVSYGHVAACQLIGPHTLALRVGDSQLLLQSPQVEEIMELVNAYLANPSPERPCSSSGPPSQDLSDTSPPSQHQVLEKPQGQSGCLRQLQD
What are the official names of this protein?
Pleckstrin homology domain-containing family H member 3, PH domain-containing family H member 3.
Protein: ARLY_SHEON
Sequence: MALWGGRFQGETSALFKLFNDSLPVDYRLFEQDVVGSIAWADAIASVGIITATECSDLKKALNELLVEVKGDPAIILASGAEDIHSFVESALIAKVGDLGKKLHTGRSRNDQVATDLKLWCQSEGAALVARLQTLRSELIALAEREFDAVMPGYTHLQRAQPVTFGHWCLAYVEMIERDFSRLTDALKRANTCPLGSGALAGTAYQMDRHALALALNFASPTLNSLDSVSDRDHVVELCSTASISMMHLSRMAEDLIFFNTGEAGFISLSDEVTSGSSLMPQKKNPDALELIRGKTGRVYGSLVGILTTMKALPLAYNKDMQEDKEGLFDVVDSWAICLDMAALVLSGLVVNRPNALLAAQQGYANATELADYLVSKGMPFREAHHVVGVAVVAAIAKKIPLEGFTLAEFKTFADIIEDDVYPNLTIEACLAKRDVLGGTALTQVKQAIAAKKAG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHO1_ASPFC
Sequence: MAKFRASNILGDPFALATVSISILAWLIACIASIISDIKTDYPNYSWWAVAYMFCCIMGVTIVFGSDTGLVYGVAVVGYLSTGLVLTTLAVNSLVYADESSSQAAAAGFILMSMVIVVWIFYFGSSPQATHRGFIDSFALNKESSGAYGNRPMSTAYGPRPDTMSTSAPQMYTSAQLNGFETSSPVSGYPGGGPGSENRSSSQARFGNPSASNVAGNNSGQDEVPPPTEYPYKAKAIYSYDANPEDANEISFSKHEILEVSDVSGRWWQARKSNGETGIAPSNYLILL
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.  Regulates radial hyphal growth and germination.  Involved in virulence and mediates resistance to oxidative stress (By similarity).
What are the official names of this protein?
High osmolarity signaling protein sho1, Osmosensor sho1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLSA_CROS8
Sequence: MTHTLNNELLASILEQVRPLAAQGKVADYIPALADVPADRLGIAVCTVGGECFAAGDADERFSIQSISKVLSLVLAMGRYDDDEIWERVGKDPSGQPFNSLVQLELEQGKPRNPFINAGALVVCDMLQSRLSAPKQRMLEVVRNLCGAPDIIYDTAVARSEFEHSARNAAIAYLMKSFGNFHNDVITVLQNYFHYCALKMSCAELARAFLFLANQGRAPHLDTPVISPVQARQVNALMATSGMYESSGEFAWRVGMPGKSGVGGGIIAVVPHEMSIAVWSPALDHAGNSLAGIAALEILAREIGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: UBIB_VIBVY
Sequence: MTPTELKRLYRIIKVQLEYGLDDLLPDHQLAKAPRWMRKSLFWLKNQHPEKPLGDRLRLALQELGPVWIKFGQMLSTRRDLFPPHIADPLALLQDQVSPFDGALAKAQMEQALGGPLETWFSDFDLVPLASASIAQVHTAKLKTTNQEVVLKVIRPDIRPIIDADLKLMRRMASIVAKAMPEARRLKPIEVVREYEKTLLDELDLRREAANAIQLRRNFTDSEELYVPEVYPDFSNETVMVSERIYGIQVSDITGLKANGTNMKLLAERGVSVFFTQVFRDSFFHADMHPGNVFVNPEHPENPQWIGLDCGIVGTLNSEDKRYLAENFLAFFNRDYRRVAELHVDSGWVPADTNIDEFEFAIRIVCEPIFAKPLCEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGLGRQLYPQLDLWETAKPFLEEWMMNQVGPKALINAIKDRAPYWAEKLPELPELLYDSLKQGKAMNQRMDQLYQGYRASKRQQATGKFLFGVGATLVVCSAILVDHTYEQLSLATAIAGVTFWLFSWRAYRR
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RT106_DEBHA
Sequence: MSNDQKWIKSLPSDLQNQVNALVEAHPPSLTVIHKLCEYFKTNASEHEDKRRKLSSDPEIKSEGHVPEALSGPKSEVPGQIHEQEIIFELPQISFQSPIRKKLNLIFHLLVEPGQSPKPVMSLALPTTYVPEISIHNLASSIRLCVLLPILGNSTNNTKRNIGLLCFWIHDDAASDPNKNDPIICQVNFDQVKKQLIKAGKIPAEAETQLKEMNESNQSQDGIKAINEAIINFLQKQFQLCGIHMINYLPSSSATKNKLTINTDAGVAVSSNANSVNDLVMVEAYKGARDGAVLMLTANEYNQPYIIFGFKKPILIFDISKVQHVSYSNITRLTYSMIVTVVNEKKDSKVETLEFGMIDQKYFQIMDEFIKSQGINDNSFDEDLREKVTTNANSGEGEQASEQAAPADSDDEEEDGTFQVGQEEEGESSVDEEYDSNAGSDGDSDVGEEEDDTNENNEGANPAASTEADDVVTQSKEEDDEQ
What is the function of this protein?
Histones H3 and H4 chaperone involved in the nucleosome formation and heterochromatin silencing.  Required for the deposition of H3K56ac-carrying H3-H4 complex onto newly-replicated DNA.  Plays a role in the transcriptional regulation of the cell-cycle dependent histone genes by creating a repressive structure at the core histone gene promoter (By similarity).
What are the official names of this protein?
Histone chaperone RTT106.
What is the protein family that this protein belongs to?
Belongs to the RTT106 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: YCF73_ORYSA
Sequence: MTKDETLLVFTLVVSSVSVFLFGILLFMVLISATRDFRERTKSKLVKIMIWAGIVVITFAIAVRIYPIFIFLLKERIKPLVEALYDKLPWIWEVSLSRYWDRLIDFLDRYLWACAQRIQTGIRKQKGEFVVTFSCRVKKRLYARAIEVGIHLSLLSNLFWILKTTLAVGYRLLWVLYYIISFEGFLGSFRLYLVYFGFYCLLFSGKWLRTSEDRGERQAQISGILLRGMLIECAFSVLCLEEDSNLHAL
What are the official names of this protein?
Uncharacterized protein ycf73.
What is the protein family that this protein belongs to?
Belongs to the ycf73 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YQGF_FLAJ1
Sequence: MPRILSIDYGQKRTGIAVTDEMQIIASGLTTIPTHTLIDFLKDYFAKEKVEAVLIGEPKQMNGQPSESASVINGFVTHFSNIFPDMKVIRVDERFTSKMAFQTMLDSGLSKKQRQNKGLIDEISATIMLQDYLSSKRF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTT2_MYCTO
Sequence: MLNQIVVAGAIVRGCTVLVAQRVRPPELAGRWELPGGKVAAGETERAALARELAEELGLEVADLAVGDRVGDDIALNGTTTLRAYRVHLLGGEPRARDHRALCWVTAAELHDVDWVPADRGWIADLARTLNGSAADVHRRC
What is the function of this protein?
May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool.  8-oxo-dGTP is inserted opposite dA and dC residues of template DNA with almost equal efficiency thus leading to A. T to G. C transversions.  MutT specifically degrades 8-oxo-dGTP to the monophosphate (By similarity).
What are the official names of this protein?
Putative 8-oxo-dGTP diphosphatase 2, 8-oxo-dGTPase 2, 7,8-dihydro-8-oxoguanine-triphosphatase 2, Mutator protein MutT2, dGTP pyrophosphohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: ACCA_BACC0
Sequence: MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQIARHAERPTTLDYIEHLFTDFFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGAYPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAKEAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDELIEKRYEKYMKIGQVSFSNASIWIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_NOVAD
Sequence: MASLKELKGRINSVKSTQKITKAKQMVAAAKLRKAQAAAEAARPYASRLAEVMGSLAAKVAGQDNGPLLMRGTGSNQRHLLVVVNTDKGLCGGLNSNIIKEAKLQARALEAAGKTVTFYLVGKKGRAPIRRDYPNGIAAGYDTSLVRTPGFDEAAAIAQELLALFEAGKFDVAHLVAPEFKNALTQLPVTTQIIPVPAPTNTVAIDAVVEYEPGEEEILEELLPRYVTTQIFGALLEREASEQGASMTAMDNATRNAGELINKLTIQYNRSRQAAITTELIEIIAGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y5606_RHIME
Sequence: MDWNRVEGNWKQVKGKVKEQWGKLTDDDLDQISGSREQLEGKIQERYGIEKDRVRRDIDDWYGRQTWNW
What are the official names of this protein?
UPF0337 protein RB0906.
What is the protein family that this protein belongs to?
Belongs to the UPF0337 (CsbD) family.
Protein: L_BEFVB
Sequence: MDSVDFLDSEDHDQNSWNGEEFGDDFLEYIWDQDEEESMDLINNKDYNLNSPLIIDPLVELRNWINNEKGHSESDLRSQQSFEFKEFDIIKRVLRNFINNVNLRRPEDSHHIFAKFLNQAIVTNDYWNLGETLSKIVEDIREVGASFYRGLDLDENIIIDNIRRNWNDVPQLGKSWFLKFFELHRVICVMNARSNIELKNLQSKNKLKKIKLPKELEERGHKCWIFDLDISGRWIIFDNYAYWELQRIVLNREFILMMKDVLISRFQTVLSMNVCTDEYKYTEENIETMMSLYREGDLILEEHGNKSYKGLKLLESICNLRLIKIVRKSRPKIPEFPNFENHIYSSLNDLRVERGIDLSKFSNIILREESIDMVLAFYSSFRHFGHPWIDYLTGLDKLESQVNKDCQVDIQYANLLASDLAFKILRKNFLEKKCWSVDKNKMDKKHKLYHHISHNTWPTQQIIDEFGDHWHELPIIQCYEIPDMIDISQIYSDKSHSLDRSEVLKIIKEQKHKRIPTKRVLQTLLEKPATNWPEFLKAVNDYGLDWEKLVIGLKAKERELKEEGRFFSLMSYELRDYFVSTEYLIKKYFVPLFEGLTMADDLNTVIKKMLDVSSGQGTREYEYITIANNIDYEKWNNYQRIESNGPVFTVMGRFLGLPNLFTRTHEFFQKSLIYYNQRPDLMMVRGRECLNRLGVKVCWEGQKGGLEGLRQKGWSILNYLMIERESRVRNTRVKILAQGDNQTISMCYKTESWQNEEELDNHIKNMVSNNNQIMQAIINGTEKLGLRINLDETMTSADYINYGKVPIIEGTIKGLPTKRWSRVNFTSNDQLPSTSTVINSSSTNALTVGHFSERPHDAINGHLLFGSLGLLLLDYHNPAIRGQISEFIPEANINNKLYNILLLYLDPSLGGIAGTSLTRFFIRGFPDGVTESLTFWKIVGEYTNDQDIKRLASTVGSPELSPFKPEDLDKLIEKPESLNIKHGLSSSNMIKGEVKKNIIENCSKIQNEIIRDAARNLVSEENQLFLWLRTINPLFPRFLSQFAESTYYGVTKSLINLFTNSKTIRGIYKKKYRKELDQLMIKGEVRSIFGLIKIVNRSKQFVMPIWDCSASLADSLRKRSWGKEVLGTTVPHPAEMFKGYRGGEDSCSFCRGNGSNNNYLTVLMPRGIPMKCHYRGPYYPYLGSNTKESTSILQPWEKETKVPVLKRACDLRKSINWFVTPDSLLAKSIFNNLKALTGEDWEDQIKGYKRTGSSLHRFGCSRVSSGGFSASSPSCFTWCIATTDTMCGLGEVNYDFMFQSTLVWCQMSSIIRERGNLHSKIHHYHIKCNKCLREIQEPVLESGWEYQPRNVSQILEKWRPKNMKTWGEEKIHMDIKDNDDEWDNLTVEDKSYEIGKTIGWLVGDSLLSHKRNYEFKSLFPVSIRYKLEGLPFLEGILDGFKICGSLNLTHRRNYMILKKPKLALQGTVFFLIDRSSFISEFTNFISHPKIYKAIKSLPHKIPTSYPMNLSDLGSILRSFLKQLYYRRKELIIKKSSWVFSDMRTNEVICSFGLSHLTYRILIQEGLNKDMKLRLQQCQDLYINIMTESKEELDKSSAKREIVECLRELKFVSSEIRHAVKFRYITGEKGEVQLIKEMEERRTWGDEYTGKANLLDVWYLTSQSSENKNLVKGIKIPYHSNPTISGLRINQIATGAHYKLRTLINMTRITYRDFICGGDGSGGMTSCLLRLKPLSRGVFNSLLILDDKPLHGTRPSPPTAIMELGEDSLRCVNCYDVWKEPSDLSKQETWKYFVKLKKQNSMMIDLIVLDMEIINDEVIEDIYQNTKNHLIYLLEEGGCLIIKTYLTYLLKENTNILDMLGHLFTSVQLINTNLSSMKTSEIYVLFKNYKNRLTPCLQFDRNIILDNWSFFYINKPIREEFERARELLNEDLGMGMPKELEPNPLIELSQMLQNSGVDGVAMSAISQEENLSFFSTKELAVICLIIISESHLVTTKKHKNDCNCLQKKPYSDQEIKSWMSGIIGIGLYLSLLDNKTNSFEILDYLINSDFKSIHVNFNKERELCWSINYSSNEKKGKDLWKKRFSVKDKMAFMGNWIRLLHRQKVKNQKCEYKEGRINNFLKFINKGLNLQKVKSQYEEEIAKLL
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviridae protein L family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=L and P are packaged asymmetrically towards the blunt end of the virus.
Protein: FOXA2_DANRE
Sequence: MLGAVKMEGHEHAADWSTYYGEPECYTSVSNMNTGLGMNSMNTYMTMSGMSSTANMTAANTMNMSYVNTGMSPSMTGMSPGTGAMAGMGAGMTGMSAALSPTMSPMAAQAPSMNALTSYSNMNAMSPMYGQSNINRSRDPKTYRRSYTHAKPPYSYISLITMAIQQSPSKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCDKKLSKDPSRKTSEGGSNSSSESCNGNESPHSNSSSNELKRSLSDMKSGQGLSPDHAASPTSQAQHLLAQHHSVLAHEGHLKPEHHYSFNHPFSINNLMSSEQQHHKMDLKTYEQVMHYGYGSPMAGTLSMGSMASKAGLDSPDTSYYQGVYSRPILNSS
What is the function of this protein?
May play a crucial role in specification of both the axial mesendoderm and the ventral nervous system.
What are the official names of this protein?
Forkhead box protein A2, Axial protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: ERAP2_HUMAN
Sequence: MFHSSAMVNSHRKPMFNIHRGFYCLTAILPQICICSQFSVPSSYHFTEDPGAFPVATNGERFPWQELRLPSVVIPLHYDLFVHPNLTSLDFVASEKIEVLVSNATQFIILHSKDLEITNATLQSEEDSRYMKPGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMDFQAKLGDGFEGFYKSTYRTLGGETRILAVTDFEPTQARMAFPCFDEPLFKANFSIKIRRESRHIALSNMPKVKTIELEGGLLEDHFETTVKMSTYLVAYIVCDFHSLSGFTSSGVKVSIYASPDKRNQTHYALQASLKLLDFYEKYFDIYYPLSKLDLIAIPDFAPGAMENWGLITYRETSLLFDPKTSSASDKLWVTRVIAHELAHQWFGNLVTMEWWNDIWLKEGFAKYMELIAVNATYPELQFDDYFLNVCFEVITKDSLNSSRPISKPAETPTQIQEMFDEVSYNKGACILNMLKDFLGEEKFQKGIIQYLKKFSYRNAKNDDLWSSLSNSCLESDFTSGGVCHSDPKMTSNMLAFLGENAEVKEMMTTWTLQKGIPLLVVKQDGCSLRLQQERFLQGVFQEDPEWRALQERYLWHIPLTYSTSSSNVIHRHILKSKTDTLDLPEKTSWVKFNVDSNGYYIVHYEGHGWDQLITQLNQNHTLLRPKDRVGLIHDVFQLVGAGRLTLDKALDMTYYLQHETSSPALLEGLSYLESFYHMMDRRNISDISENLKRYLLQYFKPVIDRQSWSDKGSVWDRMLRSALLKLACDLNHAPCIQKAAELFSQWMESSGKLNIPTDVLKIVYSVGAQTTAGWNYLLEQYELSMSSAEQNKILYALSTSKHQEKLLKLIELGMEGKVIKTQNLAALLHAIARRPKGQQLAWDFVRENWTHLLKKFDLGSYDIRMIISGTTAHFSSKDKLQEVKLFFESLEAQGSHLDIFQTVLETITKNIKWLEKNLPTLRTWLMVNT
What is the function of this protein?
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides.  Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules.  Preferentially hydrolyzes the basic residues Arg and Lys.
What are the official names of this protein?
Endoplasmic reticulum aminopeptidase 2, Leukocyte-derived arginine aminopeptidase, L-RAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: DAPD_PARP8
Sequence: MSQQLQQIIDNAWDNRADLSPKAAPADVREAVAHAIEQLDKGALRVAEKKDGDWVVNQWLKKAVLLSFRLEDNAPMPAGGYSQFYDKVPSKFANYTAEDFAAGGFRVVPPAIARRGSYIAKNVVLMPSYTNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNLPSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_SALPB
Sequence: MTEFDNLTWLHGKPQGSGLLKANPEDFVVVEDLGFTPDGEGEHILLRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDFSAFQLEGCKVLEYARHKRKLRLGALKGNAFTLVLREISDRRDVETRLQAIRDGGVPNYFGAQRFGIGGSNLQGALRWAQSNAPVRDRNKRSFWLSAARSALFNQIVHQRLKKPDFNQVVDGDALQLAGRGSWFVATSEELPELQRRVDEKELMITASLPGSGEWGTQRAALAFEQDAIAQETVLQSLLLREKVEASRRAMLLYPQQLSWNWWDDVTVELRFWLPAGSFATSVVRELINTMGDYAHIAE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: TMCAL_PEDPA
Sequence: MQACAVIAEFNPFHNGHQYLLEQARKVTKADLVIVIMSGNFVQRGEPALINKWERARVAINCGADLVVEIPTEYAIDSAKEFAHAGVEIAQKLGASFLAFGSENPDLDFENESKILDRQFDQRAKKYNQNFAAQLFDDTAIMNSNDILGINYAYWNSKSKRGLQLIPLQREQADHRDTEIKGSIASASAIRRAALEQSEYFNAVPKASLKAIRNAKLTSWEDFWIMLNYRLLTSTPQELRHIKGVTEGFENRILNLVDKSNSFTELMQKLKTKRYTYTRIQRSLTNILLNIQATPFNLTKTRLLATNQLGRIFIREAALGSVVMTKVTKEDFENNYAITKRADDLYQLVSPYQWGKGPIIKKNVKE
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_BORDL
Sequence: MAKDIYFNEDARKSLLSGIEKLSNAVKVTLGPKGRNVLIDKKFGSPIVTKDGVSVAREIDLENSFENMGAQLLKEVAIKTNDLAGDGTTTATVLAYAIAREGLKNVSSGINPIGIKKGIDHAVALAAEKIRKSAKKITTKEEIAQVASISANNDTSIGEKIAEAMDRVGKDGVITVEESKTFDTTISYVEGMQFDRGYLSPYFSTNKENMSVSFDDTYILICEKKISTIKELLPVLEKVVNTNKPLLIIAEDIEGDALAALVLNSVRGALKVCAIKAPGFGDRRKAMLEDIAILTGGVLVSEELGLTLENVELEQLGQAKSVKVDKDNTTIINTGNREQIRERAELIKKQIEETSSEYDKEKLQERLAKLVGGVAVINVGAVTEVELKEKKHRVEDALSATRAAVEEGVVPGGGSTLIEVAMYLDTVDVSKLSYEEKQGFEIVKRSLEEPMRQIISNAGFESSIYIHQIKTDKKGLGFDAASFKWVNMIESGIIDPAKVTRSALQNAASIAGLLLTTECAITEIKEEKNSAGGNYPMDPGMGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_HAEDU
Sequence: MLKIYNTLKREKEEFKPINPAQVGMYVCGVTVYDLCHFGHGRTFVSFDVIARYLRYSGYNLRYVRNITDVDDKIIKRALENNESCEALVERMIAEMHNDFDALNIMRPDVEPRATEHIAEIIAMVEKLIMNGHAYVAADGDVMFDVTSFNQYGALSRQNLDQLQAGARVEIKSAKKNPMDFVLWKRSKENEPSWLSPWGNGRPGWHIECSAMNNKELGEHFDIHGGGADLMFPHHENEIAQSCCAHQGEYVNYWLHTGMLTIDKEKMSKSVGNFFSIRHMLGLYDAESLRYFFLTAHYRSLLDYSTDNLDLARSALERLYTALRGCDLSVQANGGENYVTAFKTAMDDDFNTPAALAVLFEMAREVNKLKTEDQQQANALAVCLKELAAVLGLLTQDPDNFLKGEVNIDQTAEIEALIQQRNQAKANKNWAVADQVRGKLKAMNILLEDTPTGTVWRKA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIP1_CANAX
Sequence: MRGIAVFLAFISLIFASPLTVKSPLVDDFYTAPDGYESAKLGEILKLRKTPSKLSSMFFEIDIKNSWQLLVRSEDSFGNATAIVTTVIEPYNADPSKVLSYQTFEDSANIECSPSYGMQYGAPWSTVATQIDMALMVPMLKQGYYVVSPDYEGPKSTFTVGRQSGKATLDSIRAILKSNKFTGIKSDAKVAMWGYSGGSLASGWAAALQPKYAPELKKNLIGAALGGFVTNITATAEATDGTLFAGLVPNALSGLANEYPEFKEILYQKVSKAATDNLRQGTEHCIGGAILYFAEDQYFTGDDRAFPGGYGLLKEEVVNKTISENNLMQMDKDYLPDIPIFVYHGALDSIVPISNVHVTYKNWCDWGINSFEFSEDLLNGHITETIVGAPAAITWLEARFDGEPVVKGCKKTSRITNFSYPNISDSTSSIFEGILNSVTGSELGPGVTSDNITLDGLTGFLGNFIDLK
What is the function of this protein?
Hydrolyzes triglycerides.
What are the official names of this protein?
Lipase 1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
Protein: CITE2_XENTR
Sequence: MADHMMAMNHSRFQDGTNGLHHPAHRMGMGQFSNHHHHPQQHTFNSLMGEHMHYGPGNINANNSIRHAIVTGNVNGGHPNGSMAPASRFNSPFMGPVPNQGAQLTASMQLQKLNNQYFTHHPYPHNHYIPELHPANQINGTNQHFRDCNPKHSTGMPPSVSHVPAAMLPPSVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPNRVSC
What is the function of this protein?
Transcriptional coactivator or corepressor of the p300/CBP-mediated transcription complex.  May be involved in sex determination, early gonad development, left-right patterning during embryogenesis and differentiation of the adrenal cortex (By similarity).
What are the official names of this protein?
Cbp/p300-interacting transactivator 2.
What is the protein family that this protein belongs to?
Belongs to the CITED family.
What are the subcellular locations of this protein?
Nucleus.