PharMolix/UniProtQA huggingface dataset:
Protein: DRM2_ORYSJ
Sequence: MVDWASDSDNDKFEWDTDGEAETSSAPALRNIDAPGPSTRLPQDANGKANGSGALVAEFMGMGFPKEMILKAIKEIGDTDTEQLLELLLTYQAIGGDASVGNCSASACAPQTLEVDEEEDDTNWDEYDTAGNCDRTPHSDGSGDEDFFQEMSEKDEKMKSLVNMGFPEDEAKMAIDRCGLDAPVAVLVDSIYASQEAGNGYSANLSDYEDTEFSSFGGRKKTRFVDGSKKRKRYGSGPSGNQVPFDGSHEEPMPLPNPMVGFSLPNERLRSVHRNLPDQALGPPFFYYENVALAPKGVWTTISRFLYDIQPEFVDSKYFCAAARKRGYIHNLPIENRSPVLPMPPKTISEAFPNTKRWWPSWDPRRQFNCLQTCMASAKLTERIRCALGRFSDVPTPQVQKYVLDECRKWNLVWVGKNKVAPLEPDEMEFLLGYPRNHTRGVSRTERYRALGNSFQVDTVAYHLSVLRDLFPNGMNVLSLFSGIGGAEVALHRLGIHMKTVISVEKSEVNRTILKSWWDQTQTGTLIEIADVRHLTTERIETFIRRFGGFDLVIGGSPCNNLAGSNRHHRDGLEGEHSALFYDYIRILEHVKATMSAV
What is the function of this protein?
Involved in de novo DNA methylation.  Required for CpG and non-CpG methylation.  Required for normal establishment and maintenance of RNA-directed DNA methylation (RdDM) mediated by small interfering RNAs (siRNAs).  Regulates proper plant development in both vegetative and reproductive stages through DNA methylation.
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase DRM2, OsDRM2, Protein DOMAINS REARRANGED METHYLASE 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. DRM-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPB_THEP1
Sequence: MAKGSKGFIVSIMGPVVDVKFPEEELPDIYNALEVVNPQTGQKVVLEVEQLIGDGVVRTVAMDSTDGLTKGLEVVDTGAPITAPVGKEVLGRILNVIGEPVDEAGEIKAKERWPIHRPAPELVEQSTEIEILETGIKVIDLLAPFPKGGKIGFFGGAGVGKTVLVMELIRNIAIEHKGFSVFAGVGERTREGNELWLEMQESGVLGNTVLVFGQMNEPPGARFRVALTALTIAEYFRDVEGRDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLATDMGELQERITSTRRGSITSVQAIYVPADDITDPAPATTFAHLDATVVLSRRIAELGLYPAVDPLDSSSKILDPAIVGREHYEVARGVQEVLQRYKDLQDIIAILGVEELSPEDKLVVHRARRIQRFLSQPFHVAERFTGRPGRYVPIEETIRGFKEILDGKLDDVPEQAFLMAGNIDEVKERAKEMRS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1644_SHEPC
Sequence: MELTLHEARVIGCLLEKEITTPEQYPLSLNALTLACNQKTSREPVLDLSEAQVQDALDSLTKKRLISEQSGFGSRVVKYKHRFCNTEFSELQLSPAAVAIVCLLLLRGPQTPGELRTRSNRLHEFKDVIEVEDCIKQLISRTKPILKQLPREPGRRESRYVELFSETSANVVTTSDHTDKPHIPPVAALVEHGALVARVTELEQHVATLTQKFDELIASLT
What are the official names of this protein?
UPF0502 protein Sputcn32_1644.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: MUTS_STAAN
Sequence: MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRVLEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNNGYKVAICEQMEDPKQTKGMVRREVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATLLNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQATQLLLDYIHHTQKRDLSHIEDVVQYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWLMDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIERDTLRTYLNQVYDIERLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILEQSLVEEPPISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKISFNKVFGYFIEITRANLQNFEPSEFGYMRKQTLSNAERFITDELKEKEDIILGAEDKAIELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFSENKTLELVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQMGAYVPCKEAVLPIFDQIFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDEIGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHELTTLDQALPSLKNVHVAANEYKGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLKMVENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMTPIEALVKLSELQNQLK
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: CLPX_BURP6
Sequence: MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAAAGVEASLSKSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVDTTNILFICGGAFDGLEKVITDRTEKTGIGFGATVKSKQERDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDEAALMKILVEPKNALVKQYQKLFAMERVELEIRPDALQAVARKAIRRKTGARGLRSIIEQALLDVMYELPTLKGVSKVIIDDNVIEGDGKPLLIYEDTPKVAGSN
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MOAC_HELMI
Sequence: MDPLTHFDEKGGARMVDVSLKGDTRREAVARGRVLMHRDTFRRVRDGQIAKGDVLAVARLAGIMAAKRTSDLIPLCHPLSLTGVDLHFTLDELHSTVEIESRVKTTGKTGVEMEALTAVSVAALTIYDMCKAMDKNMVVSDIRLVEKTGGKSGHYIREE
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: PCDG7_PANTR
Sequence: MAAQPRGGDCRGFVLLSILLGTPWEAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERGVRIISRGRTQLFALNQRSGSLVTAGRIDREEICAQSARCLVNFNILMEDKMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQLSPNRHFSLAVQSGDDGTKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTVVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITPKLPQMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRLVTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAENNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEPGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLEPSDGPYNYDLTLYLVVAVAAVSCVFLAFVLVLLALRLRRWHKSRLLQASEGGLASVPTSHFVGMDRVQAFLQTYSHEVSLTADSRKSHLIFPQPNYVDMLISQESCEKNDSLLTSVDFQECKDDVPSIQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-A7, PCDH-gamma-A7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DNAE2_PSE14
Sequence: MTSEYAELHCLSNFSFQRGASSARELFERASRHGYQALAITDECTLAGIVRAWQASISTGLPLIIGSEMHIENGPKAVLLVESQTGYEALCKLITVARRRARKGEYRLLREDFEPSSDGLLAIWLPDIEGDAQACLAHGRWLRERFAERLWLGVELHRGADDEQRLADLLALAQSLGIPAVASGDVHMHARGRRALQDTMTAIRHHTTVAEAGHLLFANGERHLRPLDALAEHYPDWLLAESVRIARRCTFDLKQLKYEYPHELVPKGQTPTSWLRELTERGARKRWPNGLTPATRAQVEKELALITEKKFDSYFLTVHDIVEFARSQHILCQGRGSAANSAVCYALGITELNPEKSNLLFERFISRERNEPPDIDVDFEHDRREEVIQYIFRRYGRGRAALTAVASTYHGSGAMRDVAKVLGLPPDQINALAEAFSRWSDSLPSPERLREYGFDADTPILKRVLALTGELIGFPRHLSQHPGGFVISEHPLETLVPVENAAMADRTIIQWDKDDLDLVGLLKVDILALGMLSALRRTFDLVHLHRGKRWTLADLPGDDRETYEMISRADTIGVFQIESRAQMAMLPRLRPEKFYDLVIEVAIVRPGPIQGDMVHPYLRRRNKEEAITYPPKLKSVFERTLGVPLFQEQVMEVAIIAAGYTPGEADELRRAMAAWKRHGGLEPHRERLRTGMLKNGYEADFADRIFEQIKGFGSYGFPESHAASFALLTYASCWLKCHEPAAFTCALINSWPMGFYSPDQLLQDARRHHIEIRPVDVRYSDWDCSLEPLDHPDSTRNLAIRLGLRMVRGFREDDARRIETARSKRLFSDATDLTLRAGLDARAAEALADSGALRGLIGHRHRARWEVAGVEAQRPLFNDLPSEDTQVTLPLPTVAEDLMADYATLGTTLGPHPLALLRRQLAAKRFRSSQDLLSLENDRTLSVAGLVIGRQRPGTASGVTFVTLEDEFGMVNVVVWRDLAERQRKVLVGSQLLQVFGRLESKSGVRHLIAQRLYDLTPLLTGLDVRSRDFQ
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBA1_RABIT
Sequence: MSSSPLSKKRRVSGPDPKPGSNCSPAQSVLPQVPSAPTNGMAKNGSEADIDEGLYSRQLYVLGHEAMKRLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTAQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNSPLEDQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMILTDSNGEQPLSTMVSMVTKDNPGVVTCLDEARHGFESGDFVSFSEVQGMTELNGNQPIEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLSASLAEPDFVMTDFAKFSRPAQLHIGFQALHKFCAQHSRPPRPRNEEDAAELVTLARAVNSKASSAVQQDSLDEDLIRNLAFVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKESLTEDKCLPRQNRYDGQVAVFGSDLQEKLGRQKYFLVGAGAIGCELLKNFAMIGLGCGENGEIIVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVHQMNPHIRVTSHQNRVGPDTERIYDDDFFQTLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDPKFVERTLRLAGTQPLEVLEAVQRSLVLQLPQSWADCVTWACHHWHTQYSNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVSNPLHLDYVMAAANLFAQTYGLAGSQDRAAVATLLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDIPPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHRHLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR
What is the function of this protein?
Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system.  Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (PubMed:9322736).  Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress.  Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 1, Ubiquitin-activating enzyme E1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus.
Protein: KUP_PELPD
Sequence: MKHGETDSYWGGIIKSMGLVFGDIGTSPIYTLTVIIALTKPTQDNILGIISLIVWTLIILVHLEYAVLAMSLSRKGEGGEIVLREILVRMIKPGRQMAFVTFLTYLGVALLMGDGVITPAISILSAVEGTLLIPGLGGLSQNTLILIAGTIALFLFVFQYKGTDKVARAFGPIMVLWFAALALSGAISVSSHPGILAAISPHHAISFLMHNGLPGFFVLSEVILCATGGEALYADMGHLGRKPVKRAWYFVFVALVINYLGQGAFIITHPDAKNILFGMLQYQAPLFYIPFLILTILATIIASQALISGVFSIVYQGINTRMLPLLKVDYTSNQLKSQIYIGSVNWLLLCLVILIMLVFRKSANLAAAYGFAVTGTMVITGIMMTMIFSRTTKKWKVPLALFVTLVDVVFLVSNCNKLPHGGYWSLILASVPLAVILIWTRGQRGLYLALRPLDLETYLLSYEQIYKKGRIAGTGLFFVKEWNIIPPYLVHCTIRSNIVYERNVLISIVRTDEPFGVESVLECGIGTGLDGFMIKAGYMEIFDIELLLKQNGIQEKVIFYGIEDIATTNPIWRVFSVIKKLTPNFVQFNKVPAAKLQGVITRVEM
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FTMF_ASPFM
Sequence: MTVDSKPQLQRLAADADVDRMCRLLEEDGAFILKGLLPFDVVESFNRELDVQMAIPPPKGERLLADKYPPHFKYVPNVATTCPTFRNTILINPVIHAICEAYFQRTGDYWLSAAFLREIESGMPAQPFHRDDATHPLMHYQPLEAPPISLSVIFPLTEFTEENGATEVILGSHRWTEVGTPERDQAVLATMDPGDVLIVRQRVVHAGGGNRTTAGKPRRVVLAYFNSVQLTPFETYRTMPREMVESMTVLGQRMLGWRTMKPSDPNIVGINLIDDKRLENVLQLKAADSPA
What is the function of this protein?
Verruculogen synthase; part of the gene cluster that mediates the biosynthesis of fumitremorgins, indole alkaloids that carry not only intriguing chemical structures, but also interesting biological and pharmacological activities (PubMed:19763315, PubMed:23649274).  The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase ftmA (PubMed:16755625).  Brevianamide F is then prenylated by the prenyltransferase ftmPT1/ftmB in the presence of dimethylallyl diphosphate, resulting in the formation of tryprostatin B (PubMed:16000710, PubMed:21105662, PubMed:23090579).  The three cytochrome P450 monooxygenases, ftmP450-1/ftmC, ftmP450-2/ftmE and ftmP450-3/FtmG, are responsible for the conversion of tryprostatin B to 6-hydroxytryprostatin B, tryprostatin A to fumitremorgin C and fumitremorgin C to 12,13-dihydroxyfumitremorgin C, respectively (PubMed:19226505).  The putative methyltransferase ftmMT/ftmD is expected for the conversion of 6-hydroxytryprostatin B to tryprostatin A (Probable).  FtmPT2/FtmH catalyzes the prenylation of 12,13-dihydroxyfumitre-morgin C in the presence of dimethylallyl diphosphate, resulting in the formation of fumitremorgin B (PubMed:18683158).  Fumitremorgin B is further converted to verruculogen by ftmOx1/ftmF via the insertion of an endoperoxide bond between the two prenyl moieties (PubMed:19763315).  In some fungal species, verruculogen is further converted to fumitremorgin A, but the enzymes involved in this step have not been identified yet (Probable).
What are the official names of this protein?
Verruculogen synthase, Fumitremorgin biosynthesis protein F.
What is the protein family that this protein belongs to?
Belongs to the PhyH family.
Protein: EF1A3_HUMAN
Sequence: MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFKVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHMAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPPLGRFAVRDMRQTVAVGVIKAVDKKAAGAGKVTKSAQKAQKAK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Putative elongation factor 1-alpha-like 3, EF-1-alpha-like 3, Eukaryotic elongation factor 1 A-like 3, eEF1A-like 3, Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_STRPI
Sequence: MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEKIASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLEAGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQLGEA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PHAC_HALMT
Sequence: MTPVTFALDLQRRQWEQAAELVDRTSAASDRAETVSEVSVGKTPNEVVYKENKLRLLHYESKTETQYDVPILIVYALINRPYILDLQPDRSVVQTLLEQGFDVYLIDWGEPSRLDTHLTLDDYVTRYIDNCVDIVRDRSGQDSINLLGYCMGGTMSVMYAALFPEKVRNLGLMAAGLVFDDTGGVLERWGDEQYYSPKAVTDAFGNVPSEFLDVGFALMDPVENFVTKYVRLFENVENESFVENFSRMEQWLSDGIDVAGETYKQFLEDVYQQNKLAQNELMLDGKQVDLERLEMPILQIVGEYDHLIPPEASKPFNDLVPSEDTEVIEGATGHIGLSVSSRSHGDLWPAVSDWFAERSETGTDETPDSETEETRPDSQAEETDETPDEGLKPQAAASNETVAEEPEPQVVESNETTEEELEPQAVEANETAPEELESIDGIGPTYAERLASVGITSVSGLAAADPSEIAATIDVPVSRVTAWVEQASDRTD
What is the function of this protein?
Involved in the production of polyhydroxyalkonic acids (PHAs), which are water-insoluble biopolymers used as intracellular energy reserve material when cells grow under conditions of nutrient limitation.  PHAs are composed primarily of 3-hydroxybutyric acid (3HB) and 3-hydroxyvaleric acid (3HV).  Required for the production of poly-beta-hydroxybutyrate (PHB) and poly(beta-hydroxybutyrate-co-beta-hydroxyvalerate) (PHBV).
What are the official names of this protein?
Poly(3-hydroxyalkanoate) polymerase subunit PhaC, PHA polymerase, PHB synthase subunit PhaC, Poly(3-hydroxybutyrate) polymerase subunit PhaC, PHB polymerase, Polyhydroxyalkanoic acid synthase subunit PhaC, PHA synthase.
What is the protein family that this protein belongs to?
Belongs to the PHA/PHB synthase family.
Protein: SNU13_YARLI
Sequence: MSEPNPKAFPLADAALTQQILDIVQQATHLRQLKKGANEATKTLNRGISEFIIMAADAEPIEILLHLPLLCEDKNVPYIFVPSKVALGRACGVSRPVISASVTSNDASQLKDQIIQMKDKIERLLI
What is the function of this protein?
Common component of the spliceosome and rRNA processing machinery.  In association with the spliceosomal U4/U6. U5 tri-snRNP particle, required for splicing of pre-mRNA.  In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs.  Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
What are the official names of this protein?
13 kDa ribonucleoprotein-associated protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MUTS_BORBR
Sequence: MSQVIDSKHTPMMQQYLRLKAEAGPLLLFYRMGDFYEMFYEDAERAARLLNLTLTKRGNSNGTPIPMAGIPVHAMEQYLARLVALGESVAICEQIGDPAAAKGPVERRIVRIVTPGTLTDEALLPAKADRALAAVCVTGKREPRAGLAWLNLASGAFHVTECAPGQLESELHRIAPAELIQAESAELHMAFEGARTRVPDWHFEADGARAQLLAHFKTDSLGGFDVEDMPAAVCAAGALLRYAARTQSQALAHVQTIAAERPGQYVLLDPVTRRNLELTQTLSGEESPTLFSLLDGCRTPMGSRLLRRWLHHPLRENEPVLARQHAIATMLTARQEGEQAFAAAALLETLRDALNAFPDIERIAARVALRSVRPRELASLRDALVALPALHASLAPLSGSPRARELAAQLAMPPDIGELLARAVASEPAVAIRDGGVIAAGFDSELDELRALATDGGDFLVQLEARERERTGIGNLRVEFNRVHGFYIEVSKGQTDKVPEDYRRRQTLKNAERYITPELKTWEDRVLSAQDRSLAREKWLYEQLLDALAQYVRPLSQCASALAELDTLAALAEHARRHDWVAPELIDGAEIDIEAGRHPVVERAIERFTPNGCRLDQTRRMLLITGPNMGGKSTYMRQVALIALLARTGSFVPATRARVGRLDRIFTRIGAADDLAGGRSTFMMEMTEAAAILAASTPASLVLMDEIGRGTSTYDGLALAWAIAYRLLTHNRALTLFATHYFELTRLPAEQPTAANVHLAAAESAGGIVFLHEVREGPASRSYGIQVAQRAGVPAAVIRQASRELERLEAQGAPTPQLGLFAAALDADVQSQAMTEQAEDAAALAQLRDQLAAIDPDSLTPREALDALYRLKQHLT
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: KDGD_BRASB
Sequence: MSKMTPQEMAAKIGSGLLSFPVTPFKADYSFDEATYRANMDWLCGYEVAGLFAAGGTGEFFSLTPAEVPEVVRVAVDETRGRVPVLAGTGYGTAIAREIAIGAEKAGADGLLLLPPYLTHAEQDGLAAHVEAVCKSVKIGVIVYNRDNAILQPDTLARLCERCPNLVGYKDGIGDIELMTRVYSKMGDRLTYIGGLPTAETFALPYLDMGVTTYSSAVFNFVPEFATNFYAAVRKRDHATIHAGLKDFILPLIAIRNRKKGYAVSIIKAGMKVIGRDSGPVRLPLTDLTETEMAELTALVKALPAAAVSQAAE
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase, 5-keto-4-deoxy-glucarate dehydratase, KDGDH.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
Protein: MARH6_HUMAN
Sequence: MDTAEEDICRVCRSEGTPEKPLYHPCVCTGSIKFIHQECLVQWLKHSRKEYCELCKHRFAFTPIYSPDMPSRLPIQDIFAGLVTSIGTAIRYWFHYTLVAFAWLGVVPLTACRIYKCLFTGSVSSLLTLPLDMLSTENLLADCLQGCFVVTCTLCAFISLVWLREQIVHGGAPIWLEHAAPPFNAAGHHQNEAPAGGNGAENVAADQPANPPAENAVVGENPDAQDDQAEEEEEDNEEEDDAGVEDAADANNGAQDDMNWNALEWDRAAEELTWERMLGLDGSLVFLEHVFWVVSLNTLFILVFAFCPYHIGHFSLVGLGFEEHVQASHFEGLITTIVGYILLAITLIICHGLATLVKFHRSRRLLGVCYIVVKVSLLVVVEIGVFPLICGWWLDICSLEMFDATLKDRELSFQSAPGTTMFLHWLVGMVYVFYFASFILLLREVLRPGVLWFLRNLNDPDFNPVQEMIHLPIYRHLRRFILSVIVFGSIVLLMLWLPIRIIKSVLPNFLPYNVMLYSDAPVSELSLELLLLQVVLPALLEQGHTRQWLKGLVRAWTVTAGYLLDLHSYLLGDQEENENSANQQVNNNQHARNNNAIPVVGEGLHAAHQAILQQGGPVGFQPYRRPLNFPLRIFLLIVFMCITLLIASLICLTLPVFAGRWLMSFWTGTAKIHELYTAACGLYVCWLTIRAVTVMVAWMPQGRRVIFQKVKEWSLMIMKTLIVAVLLAGVVPLLLGLLFELVIVAPLRVPLDQTPLFYPWQDWALGVLHAKIIAAITLMGPQWWLKTVIEQVYANGIRNIDLHYIVRKLAAPVISVLLLSLCVPYVIASGVVPLLGVTAEMQNLVHRRIYPFLLMVVVLMAILSFQVRQFKRLYEHIKNDKYLVGQRLVNYERKSGKQGSSPPPPQSSQE
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes 'Lys-48'-linked ubiquitination of target proteins, leading to their proteasomal degradation (PubMed:15673284).  Promotes ubiquitination of DIO2, leading to its degradation (PubMed:19651899).  Promotes ubiquitination of SQLE, leading to its degradation (PubMed:24449766).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.  May cooperate with UBE2G1 (PubMed:15673284).
What are the official names of this protein?
E3 ubiquitin-protein ligase MARCHF6, Doa10 homolog, Membrane-associated RING finger protein 6, Membrane-associated RING-CH protein VI, MARCH-VI, Protein TEB-4, RING finger protein 176, RING-type E3 ubiquitin transferase MARCHF6.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CCM1_CANDC
Sequence: MIRLIRGNNVPSLVFKRSLFVPSNSLTNKRKRRIPPLKPRSSNKEGGDIKQSRITDRNQTSRTVGVSEKLPTQIKKELKDLRSFTKVIAQHLKPEQENDSLTSAEKPDTSQLPPIDIEEATDDIFGQISGTKKSSVEVAPPPPPPGLDIPDEIKERLGLLSELLVPEKSSNSKLPEKQVENNWKLLLSQLDQAGGLSGLSKRTISKFFSKIPPKNLKGLIPIIENMYNKAEMSIPHPIYYMFVRSLTLGDKISDTQMQLIDKYFQEISKQTDLKIDHYETMILAQVKNNHMEKIDGILALMKTKNIEISKMIYTSIVRGYIFYQKDHQKALETFDSMKFLSQKTQPDEKVYTDVIVSCIMHREIEKALDLYYELKDKGMNVNQNLLSTLAKGCSRSKQFKTQAWNFLFQIYDHGWVPNLQTYEHMLYIAARDGDVELTRALFYKMLQTNSVTVRAFRYLILSYSKYVPPHKRKERYLILLNHKGQLFRENILQDVDFSKPIHGFPFLPSSHIPDSKFVLAESSAIWAHTVMNNPSFLRQQTLVASYVSIALELDDFTEFKNRFNSASYLNKDGIPKVREIEIIEPQQDEPTETVTATEQQNTSSNTSVIRSPILNQLQQNINDNQFKAPRDSYLYNLAIKAAGKFKNYGFAQEILHERGQFRKSNSFKSLSPKQQHQDDFQFAGYLVECWTNMNLLEDAYAVVLSSIDRFPWSWRELGVLNNAAMKLGSLELAEAVRKVAQVTQVKHHGKIKRQDFKTYVMKRGY
What is the function of this protein?
RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts.  Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).
What are the official names of this protein?
Mitochondrial group I intron splicing factor CCM1.
What is the protein family that this protein belongs to?
Belongs to the CCM1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GPMA_DESVH
Sequence: MARLILLRHGQSAWNLENRFTGWTDVDLSPAGEAEALAAARLIRDEGLDFSVCHTSMLTRAIRTLHLVQQELDRLWTPVRKHWRLNERHYGALQGLDKRETAARHGEDQVFVWRRSYDVPPPVIAPDDPKHPVHDPRYADVPPDVLPCGESLEATVARVLPYWYDAIAPDLMAGRDVLVAAHGNSLRALVMHLDGLDREDVSRLDIPTGLPRLYELDAALRPVSYRYLGDPAEAEERARAVAAQGRLEKN
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: RS9_STRPM
Sequence: MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADLRLIINQPFAVTSTEGSYDVFVNVVGGGYGGQSGAIRHGIARALLQVDPDFRDSLKRAGLLTRDARMVERKKPGLKKARKASQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RL25_SALG2
Sequence: MFTINAEVRKEQGKGASRRLRTANKFPAIIYGGSEAPIAIELDHDQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.