PharMolix/UniProtQA huggingface dataset:
Protein: RS3A_AEDAE
Sequence: MAVGKNKGTSKGGKKGSKKKVVDPFTRKDWYDVKAPNMFSNRQVGKTLVNRTQGTRIASDGLKGRVFEVSLADLQNDTDAERSFRKFKLIAEDVHGRNVLCNFHGMDLTTDKLRSMVKKWQTLIECSVDVKTTDGYLLRVFCIGFTIKDSVSQRKTCYAQHSQIKEIRRKMTTIITRDVTSSDLKEVVNKLLPDSIAKDIEKSCQGIYPLHDVYIRKVKVLKKPRFDLANLLELHGDGGGKGAEVSTGAAEGGVTIDRPEGYEPPVQESV
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPB_STRCO
Sequence: MNTDTQKHEDAMSTTTPARAPHDDAPSGQQPGQGRVGAGLFEPKQLVKSLPDAFRKLDPRVMAKSPVMFVVLVGSVLTTAFSVTEPGDWFGWTISAWLWLTVLFANLAEAVAEGRGKAQADTLRRAKTDTVARRADGTTVPGTGLTVGDLVVCEAGDVIPGDGDVVEGVASVDESAITGESAPVIRESGGDRSAVTGGTKVLSDRIVVRITTKPGETFIDRMINLVEGAARQKTPNEIALNILLASLTVVFLLACATLPPFADYAGTHLDMIVLVALLVCLIPTTIGALLSAIGIAGMDRLVQRNVLAMSGRAVEAAGDVSTLLLDKTGTITLGNRQAAEFVPVRGVTEAELADAAQLSSLADETPEGRSIVVLAKEKYGLRERHQGELVGAEWIGFTAQTRMSGVDADGRKVRKGAAGSVVAWVRERGGSGTEDADTAVERISAAGGTPLLVAVEDERGARVLGVVHLKDVVKQGMRERFDELRRMGIRTVMITGDNPLTAKAIADEAGVDDYLAEATPEDKMALIKREQAGGKLVAMTGDGTNDAPALAQADVGVAMNTGTSAAKEAGNMVDLDSNPTKLIEIVEIGKQLLITRGALTTFSIANDVAKYFAIIPALFAAVYPGLDKLNIMGLSSPDSAILSAVVFNALIILVLVPLALKGVRYRPTSADRMLRRNLGVYGLGGLVAPFIGIKLIDLIVSLIPGIG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VL1_HPV07
Sequence: MWQLNENQVYLPPPTPVATIVSTDEYVQRTSLYYHAGSTRLLTIGHPYFELKKPNGDVSVPKVSGHQYRVFRVRLPDPNKFGLSDTSLFNSETQRLVWACVGVEVGRGQPLGVGISGHPYFNKDEDVENSSVYGTVPGQDSRENVAMDYKQTQLCIVGCTPPIGEYWGMGTPCNASKVSPGDCPVLELKSEVIEDGDMVDAGFGAMDFASLQANKSDVPLDLCTSISKYPDYLGMAAEPYGNSLFFFLRREQMFVRHFFNRAGTTGDSVPNDLYITGSSNRASIAGSIYYSTPSGSLVTSDSQIFNKPLWIQKAQGHNNGICFGNQLFVTVVDTTRSTNLTLCAATQSPTPTPYDNSKFKEYLRHGEEFDLQFIFQLCVITLNAEVMTYIHAMDSSLLDDWNFKIGPPASATLEDTYRFLTNKAIACQRDAPPKEKEDPYKKYKFWEVNLTEKFSSQLDQFPLGRKFLMQAGLRTGPKFKSRKRPAPTSSSSSGSVTPKRKKTKR
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: LPXD_BURP6
Sequence: MALTLEALAARFGGEIVGDGRCEVGALAPLDQAGPRQLAFLANPKYLAQVETTGAGAVLIAPGDLEKLGAAAHGRNFIVTPNPYAYFARVAQMFIDLAAPPRAAGVHPSATIDPAAQVAASAVIGPHVTVEAGAVIGERAQLDANVFVGRGTRIGDDSHLYPNVAIYHGCTLGPRAIVHSGAVIGSDGFGFAPDFVGEGDARTGAWVKIPQVGGVKVGPDVEIGANTTIDRGAMADTVIDECVKIDNLVQIGHNCRIGAYTVIAGCAGIAGSTTIGKHCMIGGAVGIAGHVTLGDYVIVTAKSGVSKSLPKAGIYTSAFPAVEHGDWNRSAALVRNLDKLRDRIKALETALAAREGDAGGA
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RL14_METCA
Sequence: MIQMQTCLDVADNSGARQVMCIKVLGGSKRRYANVGDIIKVSVKDAIPRGRVKKGEVYNAVVVRTRKGVRRADGSLIRFDNNAAVILNNQHQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: TET14_ARATH
Sequence: MKSQSHKPWNLVAGIFFPIITFFLSAPLVGHALYLFCMRNDHVYYRDFQSTLPRVQTLVSVSLLALFLLSNIGMFLRPRRLSYFLVIVFFIGFAYSGVYKMESRRFSPTPMCFKGEYNNGQGERKTEQYQVVKIEQSQGRLQRVHLRFVNSYALPPYDRRLLPSVKTGCCNRPGNCKLETVNATLWVTRNREGPPLETAMIYDRYGGNADIKDYYDMWRHELSVLYYDCMTCQVRIIKSPRLRKWWQFGVFLSSLTSLFR
What is the function of this protein?
May be involved in the regulation of cell differentiation.
What are the official names of this protein?
Tetraspanin-14.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FENR_ORITI
Sequence: MLSKNVHTTDVVIVGAGPVGLFAVFQAGMLEMKCHVVDALDCIGGQCVTLYPDKPIYDIPAYPVITAAELIEQLKQQSAPFDTVYHLGQQVIGCKIDNDMITITTSAEQVICAKSLIIAAGCGAFKYKRLTLDNIEAFENKTVFYSVKDKNKFINKKVVIAGGGDSAIDWTLLLSDVAEVIYLVHRRENFRCAPHSLNQIKKLAECGKVQMIVPYQLAKLTGENGLLQEVLVTNFDGGAQTLPADYLLAFFGLAADLGPIHKWGLKTDLRRIEVNSITYETTIPGIYAIGDVASYPGKLKLILTGFAEAATAMSHCYQRVFGKKMHFQYSTVKGVLRS
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: TEG3_HHV11
Sequence: MDRDAAHAALRRRLAETHLRAEIYKDQTLQLHREGVSTQDPRFVGAFMAAKAAHLELEARLKSRARLEMMRQRATCVKIRVEEQAARRDFLTAHRRYLDPALGERLDAVDDRLADQEEQLEEAATNASLWGDGDLAEGWMSPADSDLLVMWQLTSAPKVHANGPSRIGSHPTYTPTPTGPPGAPAAPLSRTPPSPAPPTGPATDPASASGFARDYPDGE
What is the function of this protein?
Contributes to the nuclear transport of the viral transcriptional activator VP16 during the early phase of infection.  Therefore, participates indirectly in the regulation of the immediate-early gene expression.  Additionally, seems to be important for efficient nuclear targeting of capsids.  The UL51-UL14 complex regulates final viral envelopment for efficient viral replication (PubMed:27440890).
What are the official names of this protein?
Tegument protein UL14.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL14 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: ISPD_CLOB6
Sequence: MSKNSVIIVAAGKGKRMNSSISKQFLQIKNKPILYYTLNKFSTHESIDEIVLVALEDKIEVCSDIIDKYNINKVSKIVPGGKERQDSVYNGLKAVSKDCEVVLIHDAARPFVTSDIIENGIRYVNQYGAAACGVIPKDTVKIKDEKGFAIDTPNREDLFIVQTPQCFNYNIILDCHEKLKKHNKKVTDDTMVLENYGKSVYLYEGSYSNIKITTPEDLILGEQILEKLT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: JOSL_DROME
Sequence: MESPSARTLGNSLGDDSGNGNENGNGSGNGNTTMMPHGIYHERQTRHLCGLHALNNLFQGPDMFSKSELDDYCTTLTPRNWLNPHRSWIGWGNYDVNVIMYALQQRNCEAVWFDRRRDPHCLNLSVIFGFILNVPAQMSLGYYIPLPFHMRHWLALRRLNGSYYNLDSKLREPKCLGTEQQFLEFLATQLQMDHELFLVLDEETDCKDKSQQRWLLPQFRD
What is the function of this protein?
May act as a deubiquitinating enzyme.
What are the official names of this protein?
Josephin-like protein.
Protein: NDHI_LIRTU
Sequence: MFPMMTGFMNYGQQTVRAARYIGQSFMITLSHANRLPVTIQYPYEKSITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWRLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSVIGDYTIRTIMNSTQIKIATDNPLDSRTITNY
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: FOXP1_HUMAN
Sequence: MMQESGTETKSNGSAIQNGSGGSNHLLECGGLREGRSNGETPAVDIGAADLAHAQQQQQQALQVARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQVLLQQQQALMLQQQQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQLAFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLAQGMIPTELQQLWKEVTSAHTAEETTGNNHSSLDLTTTCVSSSAPSKTSLIMNPHASTNGQLSVHTPKRESLSHEEHPHSHPLYGHGVCKWPGCEAVCEDFQSFLKHLNSEHALDDRSTAQCRVQMQVVQQLELQLAKDKERLQAMMTHLHVKSTEPKAAPQPLNLVSSVTLSKSASEASPQSLPHTPTTPTAPLTPVTQGPSVITTTSMHTVGPIRRRYSDKYNVPISSADIAQNQEFYKNAEVRPPFTYASLIRQAILESPEKQLTLNEIYNWFTRMFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEFQKRRPQKISGNPSLIKNMQSSHAYCTPLNAALQASMAENSIPLYTTASMGNPTLGNLASAIREELNGAMEHTNSNESDSSPGRSPMQAVHPVHVKEEPLDPEEAEGPLSLVTTANHSPDFDHDRDYEDEPVNEDME
What is the function of this protein?
Involved in transcriptional regulation in embryonic stem cells (ESCs).  Stimulates expression of transcription factors that are required for pluripotency and decreases expression of differentiation-associated genes.  Has distinct DNA-binding specifities as compared to the canonical form and preferentially binds DNA with the sequence 5'-CGATACAA-3' (or closely related sequences) (PubMed:21924763).  Promotes ESC self-renewal and pluripotency (By similarity).
What are the official names of this protein?
Forkhead box protein P1, Mac-1-regulated forkhead, MFH.
Protein: FUMH_DANRE
Sequence: MYRSARSLHRFSASLSDLRAAQRSIKARNVCPAPGLRHQTVRMASSEAFRIERDTFGELKVPSDKYYGAQTVRSTMNFRIGGVTERMPIQVIRAFGILKKAAAEVNKDYGLDPKIADAIMKAADEVESGKLDDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGKLGSKDPVHPNDHVNKSQSSNDTFPTAMHIAAAKEVHEVLLPGLQTLHDALAAKAEQFKDIIKIGRTHTQDAVPLSLGQEFGGYVQQVKYSIARVKASLPRVYELAAGGTAVGTGLNTRIGFAEKVADKVSALTGLPFVTAANKFEALAAHDALVELSGALNTVAVSMMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMIIKNVLNSARLLGDASVSFTNNCVVGIEANTERINKLMSESLMLVTALNPHIGYDKAAKIAKTAHKDGSTLKEAALKLGFLNEQQFEEWVRPHDMLGPK
What is the function of this protein?
Catalyzes the dehydration of L-malate to fumarate.  Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by-product of the urea cycle and amino-acid catabolism (By similarity).  Also plays a role in DNA repair by promoting non-homologous end-joining (NHEJ).  In response to DNA damage translocates to the nucleus and accumulates at DNA double-strand breaks (DSBs): acts by catalyzing formation of fumarate (By similarity).
What are the official names of this protein?
Fumarate hydratase, mitochondrial, Fumarase.
What is the protein family that this protein belongs to?
Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm, cytosol. Nucleus. Chromosome. Note=Translocates to the nucleus in response to DNA damage: localizes to DNA double-strand breaks (DSBs).
Protein: TOP1_OXYTA
Sequence: FRGLAKLLKIGLKSFARVLKKVLPKAAKAGKALAKSMADENAIRQQNQ
What is the function of this protein?
Disrupts cell membranes, particularly those rich in phosphocholine, through formation of pores.  Has antimicrobial activity against Gram-negative bacterium E. coli, Gram-positive bacteria B. subtilis and S. aureus, and hemolytic activity against sheep, pig and guinea pig erythrocytes.  Has insecticidal activity against S. frugiperda ovarian cells by opening non-selective ion channels.  Enhances the insecticidal activity of spider venom neurotoxic peptides.
What are the official names of this protein?
M-oxotoxin-Ot1a, M-OXTX-Ot1a, Oxki1, Oxyopinin-1.
What is the protein family that this protein belongs to?
Belongs to the cationic peptide 02 (oxyopinin-2) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a transmembrane alpha-helix in the target cell membrane. Forms a membrane channel in the prey.
Protein: DGCQ_SALTI
Sequence: MPHETLLDNQGWFKKLARRFGPGHVVNTCFLIVMLFSTLLTWREVMILKDAYVASQRNHLGSVANVLDRQLQFNMDRLIFLRNGMHEALVAPLAFSALQSAVTQFEQRRVRHFWQLELDKRRTLPLYGVSDQFVARTTLLSRESRDLANELTATLELGYLARSSAMLTLETMYVSRSGFYLSTLPTAYGSDIVSRYYQYVTQPWFIEQSQRRNPQRGVRWFTSAQPYVADEQKKVTASLPLDHDNYWYGVLAMDIPVASLQQFLRDAAEKDIEGEYQLYDNHLRLLTDSAPEQQTENTLNDRERALLAREIEKDTLGGLRLGTHYVSWERLDHFDGVLLRVHTLREGIQGNFGSISIALTLLWGLFTAMLLISWGVIRHMVKNMFVLQNSPQWQAWHDPLTRLYNRGALFEKASRLAKRYREARQPFSVIQLDLDYFKSVNDRFGHQAGDRVLSHAAGLIGSTIRAHDIAGRVGGEEFCIVLPGATKAQALQIAERIRQRINDKEILVTKSTTLRISASMGISSAEEYGDYDFEQLQSLADKRLYYAKQSGRNRICASDATQEREKK
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules (By similarity).  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria.  Involved in the regulation of cellulose production (By similarity).
What are the official names of this protein?
Probable diguanylate cyclase DgcQ, DGC, Cellulose synthesis regulatory protein.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRF_AGRFC
Sequence: MTAREKLIVGLDVPTVQQAEDIVSKIGDEVLFYKIGYQLVFAGGLEFARDLVQSGKKVFLDMKLLDIDNTVASGVENIARMGMSMLTLHAYPKAMRAAVKAAEGSGLCLLGVTVLTSMDDSDLVEAGYASDARSLVLRRAEQAREAGMGGIVCSAEESTAVREILGPDLAVVTPGIRPAGADLGDQKRVMTPYDAIKAGSSHLVVARPIVRAEDPKAAARAILDDMLRASFPANQ
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: DNLJ_STRE4
Sequence: MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQTYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEAEYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVTIRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQEVGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVVVKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIPTACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYSAGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGAKASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAGVNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVVAGSEAGSKLAKAQQLGIRIEDEDWLLNL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LACB1_STRA3
Sequence: MKIAIGCDHIVTNEKMAVVDFLKSKGYEVQDYGTYDHVRTHYPIYGKKVGEAVASGKAELGICICGTGVGINNAVNKVPGIRSALVRDMTSALYAKEELNANVIGFGGKITGELLMCDIIEALLHAEYKPSEENKKLIAKIAHVESKNDNQTNPDFFKEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB 1.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: RS19A_YEAST
Sequence: MPGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  eS19 is required for proper maturation of the small (40S) ribosomal subunit.  Binds to 40S pre-ribosomal particles, probably required after association of NOC4 but before association of ENP1, TSR1 and RIO2 with 20/21S pre-rRNA (PubMed:16159874, PubMed:17726054).
What are the official names of this protein?
40S ribosomal protein S19-A, RP55A, S16a, Small ribosomal subunit protein eS19-A, YP45, YS16A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCN1_HUMAN
Sequence: MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLSGKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESPGLEEELADILQGPSLRSTDEEDEDELIL
What is the function of this protein?
Voltage-gated chloride channel (PubMed:8112288, PubMed:9122265, PubMed:12456816).  Plays an important role in membrane repolarization in skeletal muscle cells after muscle contraction.  The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (Probable).  The absence of conserved gating glutamate residues is typical for family members that function as channels (Probable).
What are the official names of this protein?
Chloride channel protein 1, ClC-1, Chloride channel protein, skeletal muscle.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClC-1/CLCN1 subfamily.
Protein: RNY_DESRM
Sequence: MEFQIILVVIISALVGLVIGFFIRKNIAEGKITSAEAQAKRILEEAEKNAEGKKREAIVMAKEEVLKLRNEMEREIRDRRNELQRLERRLLQKEETLDRKMDSMEKKEESLSRKEADIENTKAELTNVLNRQLAELERVSGLSSEEARQILLNDVEKELQHDMAVMIKDFENRAKEEADKKARDIISSAIQRCAADHVAEATVAVIPLPNDEMKGRIIGREGRNIRAFETLTGIDLIIDDTPEAVILSGFDPIRREVARLALERLISDGRIHPARIEEMVEKAQKDVEVQIREAGEQATFETGVHGLHPELVKLLGRLKFRTSYGQNVLKHSIEVCHLAGLMAAELGIDVKLAKRAGLLHDIGKAVDHEVEGPHVAIGVNLCQKYKESPEVIHAIAAHHGDEEPRTIEAVLVQAADAISAARPGARRETLESYIKRLQKLEEIAGTFEGVEKSFAIQAGREIRIMVKPDKIDDLAAIRLVRDIAKKIENELDYPGQIKVIIIRETRYVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ENO_BURO1
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYNGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILSDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHESDWDGWKLLTDRLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
Protein: NIKR_CALS4
Sequence: MLLFSKKIAQHKGGICLEGIVRFGVSMESKLLKQFDELIKKKNYNNRSEAIRDLIRDFIVENQWEAEDVETIGTITYVFNHEVREINDKLTDMQHKHYKNIISTMHVHLDEHNCIEVMIVRGKAKEIVKIADEIISTRGVKHGKLVMTTTGENL
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: YPFN_SALEP
Sequence: MDWLAKYWWILVLVFLVGVLLNVIKDLKRIDHKKFLANKPELPPHRDFNDKWDDEEDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: APA_MYCTU
Sequence: MHQVDPNLTRRKGRLAALAIAAMASASLVTVAVPATANADPEPAPPVPTTAASPPSTAAAPPAPATPVAPPPPAAANTPNAQPGDPNAAPPPADPNAPPPPVIAPNAPQPVRIDNPVGGFSFALPAGWVESDAAHFDYGSALLSKTTGDPPFPGQPPPVANDTRIVLGRLDQKLYASAEATDSKAAARLGSDMGEFYMPYPGTRINQETVSLDANGVSGSASYYEVKFSDPSKPNGQIWTGVIGSPAANAPDAGPPQRWFVVWLGTANNPVDKGAAKALAESIRPLVAPPPAPAPAPAEPAPAPAPAGEVAPTPTTPTPQRTLPA
What is the function of this protein?
A potent antigen in animals immunized with live bacteria, it induces a strong delayed-type hypersensitivity (DTH) in immunized animals (PubMed:10531201).  Elicits a mostly Th1 type of T-cell response in healthy humans; induces IFN-gamma production from CD4(+) and CD8(+) cells (PubMed:12654810).  Functions as an adhesin, binds to mouse macrophages via mannose residues (PubMed:10531201, PubMed:25359607).  Might interact via host CD209 (PubMed:16092920).
What are the official names of this protein?
Alanine and proline-rich secreted protein Apa, 45 kDa glycoprotein, 45/47 kDa antigen, Antigen MPT-32, FAP-B, Fibronectin attachment protein, Immunogenic protein MPT32.
What is the protein family that this protein belongs to?
Belongs to the Apa family.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: VG36_ICHVA
Sequence: MDGIFPSTDKMLYENVTIWREASGEYQTATTLSHYNHALPDSGSPCDEFRASLKKNGISSLLTTRGPVTCIKFQIPEDKVISLETLACLEGTIKVVGDYCYITVTTGDTVLEPPTPSQPAPTPEPAVKPQPIATRKRSGLSALLWPF
What are the official names of this protein?
Uncharacterized protein ORF36.