PharMolix/UniProtQA huggingface dataset:
Protein: COX1_OENBE
Sequence: MTNPVRWLFSTNHKDIGTLYFIFGAIAGVMGTCFSVLIRMELARPGDQILGGNHQLYNVLITAHAFLMIFFMVMPAMIGGSGNWSVPILIGAPDMAFPRLNNISFWLLPPSLLLLLSSALVEVGSGTGWTVYPPLSGITSHSGGAVDSAISSLHLSGVSSILGSINFITTISNMRGLGMTMHRSPLFVWSVLATAFPILLSLPVLAGAITMLLTDRNFNTTFSDPAGGGDPILYQHLFRFFGHPEVYILILPGSGIISHIVSTFSGKPVFGYLGMVYAMISIGVLGFLVWAHHMFTVGLDVDTRAYFTAATMIIAVPTGVKIFSWIATMWGGSIQYKTPMLFAVGSIFLFTVGGLAGIVPANSGLDIALHDTYYAGAHFHYVLSMGAVFALFAGFRYWVGKIFGRTYPETLGQIHFWITFFGVNPTFFPMHFLGLSGMPRPIPDYPESYAGWNALSSFGSYISVVGIRCFFVVVTITSSSGNNKRCAPSPWAVEKNSTTLEWMVQSPPAFHTFGELPATKETKSYVK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IHFB_HAEIG
Sequence: MTKSELMEKLSAKQPTLPAKEIENMVKDILEFISQSLENGDRVEVRGFGSFSLHHRQPRLGRNPKTGDSVNLSAKSVPYFKAGKELKARVDVQA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RS7_GEOTN
Sequence: MPRRGPVAKRDVLPDPIYNSKLVTRLINKIMIDGKKSKAQKILYTAFDIIRERTGKDPMEVFEQALKNVMPVLEVRARRVGGANYQVPVEVRPDRRVSLGLRWLVQYSRLRGEKTMEERLANEIMDAANNTGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: BEND6_HUMAN
Sequence: MQKIVQTDEITNTQAFRKGKRKRTETMDSENANSDMDKGQRDPYSGNAFLPGESSSEDEEPLAELSKEELCAKIKSLKEKLTNTRKENSRLRQSLVMLQVLPQAVTQFEELVGMAEALLKGGGTMSTSASTLWRATNNSSPDSFASTCSNSNSNSSSPVSLKPEEEHQTDEKQFQIEKWQIARCNKSKPQKFINDLMQVLYTNEYMATHSLTGAKSSTSRDKAVKPAMNQNEVQEIIGVTKQLFPNTDDVSIRRMIGQKLNNCTKKPNLSKNLNSQDIK
What is the function of this protein?
Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis (PubMed:23571214).
What are the official names of this protein?
BEN domain-containing protein 6.
What are the subcellular locations of this protein?
Nucleus.
Protein: MLK1_CAEEL
Sequence: MEQASVPSYVNIPPIAKTRSTSHLAPTPEHHRSVSYEDTTTASTSTDSVPEVRIRSESSQVSRESPPIRASKAFVASYEYEAQKDDELNLPLGAIITLVTVETNEDGWYRGELNGKVGLFPSNYAREVTYKDNLVEFKQDEIMLPVAVRTLSDCQIGHGATATVFKMDIKIKKELQNGRMGEAVGDQMKAALKRFNRHASNFRADVVSTDEQLEQLKREANLVNGLSHNNIVRLLGICLEDPYFGLLLELCEGSSLRNVCRNLNSDAAIPLGVLIDWATQVAEGMEYLTKQGYVHRDLKADNVLVKEEVCLCMDEEMFQYAYCLKCGKRPFDKLQLKITDFGVTRKMTADANRFSTAGTYAWLAPEAFKEGTWSEASDVWSYGVVLWELLTREEPYQGHIPATIAFQIANKGQNLSIGDSCPDRWKKLMQDCWNLEPNFRPKFSTLAISFKQYAKEFKDTHLQRAPSKMAVKELYSECFADKTKEEFEKRFHDLYAGSGDINRKNRHSIAPETKARRLKHHKPKKADITGPTEVKHILSVQKDDKNFRVKTYDQSSTGGTLPRLNERQSTLSLSSPDLFHISNLISGSNTVGHSAHRISRKNAIRHKKNQHRMFESPVVSPTMDDSNTFSTIDNADEVDPNHSKESKKGGTLSRAWAKLPWNKRDSKEDHDERAVAGSISSRSSSTTSSNRLITGQTTRGASAAGLLEIGARSRAQSTADGWEDPNTTKKHKVSPSDKRPVKTTNQTERYVKDLEKDTPLRPAQLPPTHRKSALDQTIPASPNSPDSINNFHPMPLSSRRTTANSSSDGAPCYDALVSHSYGAGHGHKNHFGLSDTIPLFPEEPTHYDMGPGRPFGTNGRAIVNQGGDYYGNISGQNYEGFGHGRSINQSTQYYPVGGGCDDYIPIVQKTVIKPTVGEVGNSPYSENIRCATRNVQNPQYIQCKKNQNPRRIPALPMKIQSESNLVTSGMVFTPRDEQLNGIGNSLSSLSLNEPPDIPAPLPPVVTYPIPASLISPSNRVSMSPPTRMAPVLPLGAMSSPRIMDKEILKNSSVEGTEIY
What is the function of this protein?
Serine/threonine-protein kinase which, by phosphorylating and activating mek-1, plays an important role in the activation of the JNK pathway composed of mlk-1, mek-1 and kgb-1 (PubMed:15116070, PubMed:20008556).  Involved in the response to environmental stress such as heavy metals (PubMed:15116070, PubMed:18809575).  By activating the JNK pathway downstream of tyrosine receptor svh-2, plays a role in axon regeneration after injury (PubMed:21670305, PubMed:23072806, PubMed:22388962).
What are the official names of this protein?
Mitogen-activated protein kinase kinase kinase mlk-1, Mixed lineage kinase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
Protein: FAR4_CALVO
Sequence: KPNQDFMRF
What are the official names of this protein?
CalliFMRFamide-4.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRF_YERPE
Sequence: MTSATKTNNSGSISSPIVVALDYANKDAALAFADQVSPQDCRLKVGKEMFTLYGPELIRDLHQRGFDVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMSAAKEALLPYGAQAPLLIAVTVLTSMDGEDLRDIGITISPAEQAERLAKLTWDCGLDGVVCSAHEAVRLKQVCGEDFSLVTPGIRPQGSEAGDQRRIMTPEQAVAVGVDYMVIGRPITQSPDPEKTLREILASLTKVA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RUVB_BDEBA
Sequence: MSRILEGDPVEGEKSWENELRPQKFEDFPGQDDVKEKLKVFVAAAKHRGESLDHVLLCGPPGLGKTTLSKIIANDMGAEIKMTSAPAIDKKGDLAAILTSLKPHSVLFIDEIHRLSRHVEEYLYTAMEDYYIDIVTGEGLGARSMKFTLAPFTLVGATTRAGLLNPPFRDRFGIVERLQFYDKDALRQILMRSAEILKVEIDEEGAEEVARRSRGTPRVANRLLKRVRDYAQVKGNGVVSKDIAVYALNQLGVDQYGLDLMDRRILSLIQDKYAGGPVGIDTIAAALSEERDTLEEVYEPFLIQEGFIQKTQRGRVITEFAKSSVLADK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: AROA_MYCTU
Sequence: MKTWPAPTAPTPVRATVTVPGSKSQTNRALVLAALAAAQGRGASTISGALRSRDTELMLDALQTLGLRVDGVGSELTVSGRIEPGPGARVDCGLAGTVLRFVPPLAALGSVPVTFDGDQQARGRPIAPLLDALRELGVAVDGTGLPFRVRGNGSLAGGTVAIDASASSQFVSGLLLSAASFTDGLTVQHTGSSLPSAPHIAMTAAMLRQAGVDIDDSTPNRWQVRPGPVAARRWDIEPDLTNAVAFLSAAVVSGGTVRITGWPRVSVQPADHILAILRQLNAVVIHADSSLEVRGPTGYDGFDVDLRAVGELTPSVAALAALASPGSVSRLSGIAHLRGHETDRLAALSTEINRLGGTCRETPDGLVITATPLRPGIWRAYADHRMAMAGAIIGLRVAGVEVDDIAATTKTLPEFPRLWAEMVGPGQGWGYPQPRSGQRARRATGQGSGG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_STAAM
Sequence: MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BORBU
Sequence: MNNNAFHFPVLLDAICKLIEDLPVKSDLIYIDSTLGEGVHAKAILEKYDFLSLVGIERDPQILERARQFLSIFEERITYFNDWFDNFFVNYPLNVKANFILVDLGISMFHYKGSKKGFSFLEDEPLDMRLCSSSCKISAAEIVNTYSKYDLEALIYDLSNEHYSRRISKAIVEYRKIKKIETTKELQSIISKVYPFSKVKINPATKTFQALRIYVNDELARLKRSLPFWVENLAKDGILAIITFHSIEDRIVKDFFRSLSCDLYAKISKKPIMPSFDEIKKNKPSRSAKLRVVKKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGUOK_XENLA
Sequence: MKSQTTKPLQQSISTNLSSNKEMQVKRLSVEGNIAVGKSTFLRLLSNTFQEWSFATEPLKKWQNIQSTSFQTTTSSKPPMDNLLQLMYDDPKRWSYTFQTFSCMSRFKIQIQPLSEPVLKQQEHVQIFERSVYSDRYIFAKTLYELQHLNEMEWTLYQEWHTFLIQEFSRRVALDGIIYLWATPEKCFERLQRRARKEEKTLQLQYLEKLHDQHESWLTKKTTEVSFENMKNIPVLLLNVEEDFENNSAAGDELNNRVKAFVAGL
What is the function of this protein?
Phosphorylates deoxyguanosine in the mitochondrial matrix with high efficiency but shows very low activity against other deoxynucleosides.
What are the official names of this protein?
Deoxyguanosine kinase, mitochondrial, XldGK.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y2791_MYCMM
Sequence: MTTSEYGSRRSDDDQWDIVSGVGYTALLVAGWRALDTVGPQPLAPDEYAKYFIAASGDAYLNDQLAHPPTSVDETAFPRLYGVQTRFFDDFFRSAAAAGTKQAVIVAAGLDSRAYRLEWPSGTTVFEIDLPQVLEFKARVLQRHGVEPKARRNEVAADLRTDWPATLHAAGFEPGQPSAWSVEGLLPYLTADAQDALFARIDDLCAPGSRIATGALGSRLDHDQLVALEQTHPGVNLSGDVNFSALTYDDKTNPAQWLAARGWVVEPVRNTLELEAGYGMTPPAVDVRLDAIMHSEYIVATKP
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_2791.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: HIS82_CUPPJ
Sequence: MSVVDPSLIERIIRDDVRAMGAYHVPDSHGLVKLDAMENPYRLPPALRSELAARLGEVALNRYPVPSSEALRAKLKEVMQVPAGMEVLLGNGSDEIISMLALAAARPGAKVMAPVPGFVMYAMSAQFAGLEFVGVPLRADFTLDRGAMLAAMAEHQPAIVYLAYPNNPTGNLFDAADMEAIVRAAQGSVCRSLVVVDEAYQPFAQESWMSRLTDFGNLLVMRTVSKLGLAGIRLGYVAGDPQWLEQLDKVRPPYNVNVLTEATALFALEHVAVLDEQAAQLRAERSRVAEGMAAHGGVTVFPSAANFLLARVPDAAQTFDRLLARKVLIKNVSKMHPLLANCLRVTVSTPEENAQFLEAFAASLQD
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: MDM12_EMENI
Sequence: MSIEVNWGTATSGPDGEALAERIRSFIHDKFQQVPLPRFIRSVQVHSFDFGTVAPDLEIKDFCEPFADFYEDDEDGDSGSEISEELQHRTHDNPWDRTQSELNETSFRDDRPVTSHHALRDPFDEDFRQHTSSPLRSPIALGDHLNPHFLPRAGTPGIPGGTSTLGYHLMSLGGLSGTQTPLAAVAGGSPFTTNWTDPSPMGQGNKTGIRPSPLHRADADIDSSNPASRPSTASTHPSGSNRSSHPDGHPEHNDDPISSSENPLLQNQPPPRMRERRPEDFQILCHVKYAGDIRLSLTAEILLDYPMPSFVGLPLKLNVTGITFDGVAVIAYIRKRVHFCFLSPEDAEALVGSGSYSGQQETPGPSTGSSGGGNPSPHQKGLSLLQEIRVESEIGRKEDGKQVLKNVGKVERFVLAQVRRIFDEELVFPSFYTFLI
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10.  The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: KYNU2_ASPOR
Sequence: MSNVKSSKPVFPENAGSNEYAASLDAADPLASFRDKFIIPSKANINSKKLAKPGLSSDPCIYFCGNSLGIQPKATAKYLEAQLDTWSSIGVSGHFVDLEGSPLKQWQLLSEQAAASMSKIVGAQAEEVAAMGTLTANLHLLLASFYKPTPTKHKILLDWKAFPSDHYAIESHLAWHNLDPKQSMVLIGPDEGEYEISTEKILSYIDEHAESAALILLPGIQYYTGQLFDIQKITAYAQSRDLTVGWDLAHAYGNVELKLHDWDVDFAAWCTYKYGNAGPGAMGGLFVHERHGRVDYSEGEDAPKFRHRLTGWYGGDRSVRFKMDNNFKPIPGAGGWQLSNPSAIDLACLCASLSVFDETSMAELRKKSVMLTAYLEHLLLKDTTDETRPFRIVTPADPEARGAQLSVLLKPGLLQNVSQKLQEGGIVCDKREPGVVRVAPTPLYNTFTDVWKFVSYFKAALDEPELKN
What is the function of this protein?
Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
What are the official names of this protein?
Kynureninase 2, Biosynthesis of nicotinic acid protein 5-2, L-kynurenine hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the kynureninase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RKM5_YEASV
Sequence: MAFKLWLLDEETIYEHVFERYTQLEGQSGKLAQDLGIQDRRGGVLEITFEPSGLEGGRKKKRVRRRNKASSVEEDQNVAVDSYHVSVGQSISSLHSSRDNGNSTTGYVLWSTTPFFINWLLYSTSAAPFRLGSQVEVTCGSSCEGHXLELPRLXDLTGADRGKRGILELGAGISGILPVILGNFVDTYVSTDQKGILNKLKDNIMENLSQLTRKRCISRSLRLELPTVEPVGDADITAASLPSKSTLHLEVAALDWEKINLQDKKTHSLHPELSLIGETCSSVYVIAMDVIYNEYLIDPFLKTLKQLKHWLQTTYNLQFHVLVGIHLRSQEVTTLFLEKAIIEYDFTVYDIVDQVIQESRFNFYLIT
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L1 (RPL1A and RPL1B) at 'Lys-46'.
What are the official names of this protein?
Ribosomal lysine N-methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RKM5 family.
Protein: MUKB_HAEAE
Sequence: THAMLLDALSGQQDEYQDLFNDNRITFSEAMAKLYQRINPHIDMGQRTAQTIGEELLDYRNYLELEVEVFRGADGWLRAESGALSTGEAIGTGMSILLMVVQSWEEESRRIRGKDIVPCRLLFLDEAARLDGKSISTLFELCERLDMQLLIAAPENISPEKGTTYKLVRKIAGNQEHVHVVGLRGFGATE
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity).
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: BIOD_RIPO1
Sequence: MNSLLITGTDTGAGKTIVTSALAAYWHKYYPSQRLGVIKLLQTGIGDHEHYQAMFAGQESVEVVCPLRFTTPVAPPIAAERENQPIPLEIVWKSLVSLQKSCDFVLAEGLGGLGSPVTWELTVADLAGEWRLPTVLVVPVKLGAIAQAVANVALARQTQVNLKGIILSCSHPLSPQELSDWAPMDLIQSLTGVPVLGVIPYLETIKDLDQLAKSASHLDLEPLISLDCRTQFLG
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring (By similarity).  This cyanobacterium does not encode bioA (which catalyzes the formation of the precursor for this reaction in the cannonical pathway), instead it encodes bioU, which replaces bioA and also performs the first half of the cannonical BioD reaction.  Thus in this organism BioD has a different substrate (By similarity).
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_PICTO
Sequence: MMPYISKNAVIIGRDRKFITDNVTVEEPLQISIENENRIYNVSVIMRTPVDDEALATGFLVNEGIIEPDKIIKVSKRSENNVCVSVESFNEDLLKNRNFYVNSSCGVCGKTDIENVFIKSHGIVRSQSRTDHSIILGLPDKMMKNQKIFSYTGGIHAAALFDLNGNMISISEDIGRHNAVDKTIGKMILKNVYRMEDSILQVSGRAGFEILQKASMFGVSIVSSVSAPSSLAIDVAETFNITLISFVRKNRMNIYSHPERIL
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_ERYLH
Sequence: MQIMVRDNNVDQALRALKKKLQREGVYREMKLRRHYEKPSEKRAREKAAAVRRARKMERKRMERDGIK
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ZUPT_ECOK1
Sequence: MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIM22_SCHPO
Sequence: MSLSGLLPPNLGGNSPNADGNLTPEEKAALQQAKIIGYMNRISESCVFKSSMAGVLGFGLGGIFGMFISSLDLQHIDPKIYEKPFREQIRIQARDMGSRSFSTAKNFGLLGLIYSGSECCIEAFRAKTDIYNAIAAGVFTGGALAVRSGPKAIVLGGAGFGLFSYGIEKYMHWGE
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y2825_BRUA2
Sequence: MTEITDRYFNDVIARLSGLRDRLAAQMEKAADLIAAAARADRRVYVFGTGHSHMMAEELHYRAGGLAITVPILCGSIMLQDGAVASSHFERIEGAVRPILDRYGIRDGDVLVVVSNSGVNAAPIEAARYAREKGAAIIALTSVAYSNTIARGRTQLLSLADVVLDNDAPSGDAVLEIAGSALKVGPVSTALGVTILNAVFADVAARLVGEGDAPIYLSANMPGSGDINRSLVERYRDHNPHL
What are the official names of this protein?
UPF0309 protein BAB2_0325.
What is the protein family that this protein belongs to?
Belongs to the UPF0309 family.
Protein: ATPI_CYACA
Sequence: MISNNLEICSIDIGVHWYWNFLGLKIHGQVLLVSWVAIIILLLLAILGTFNMQKEPRGFQNFLEYVFEFLQDISKNQIEEKYYKSWVPFISTLFLFIFVSNWLGALVPWKLIKIPEGELAAPTNDINTTVALAMLTSVSYFYAGLSKKGLRYFLKYISPTPILLPINILEDFTKPLSLSFRLFGNIVADELVVAVFNLLFPLFLPLPVMVLGLFASSIQALIFATLSASYIGESLADHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: VF205_ASFM2
Sequence: MVEPREQFFQDLLSAVDKQMDTVKNDIKDIMKEKTSFMASFENFIERYDTMEKNIQDLQNKYEEMAINLAAVMTDTKIQLGAIIAQLEILMINGTPLPAKKTTIKEATPLPSSNTNNEQSMSTYSSSISGKTSETVKKNPTNAMFFTRSEWASSKEFREKFLTPEIQAILDEQFANKTGIERLHAEGLYMWRTQFSDEQKKMVKEMMKK
What is the function of this protein?
Induces host endoplasmic reticulum stress and consequently activates autophagy and NF-kappa-B signaling pathway.  In turn, may induce autophagy-mediated STING1 degradation and innate immune evasion.
What are the official names of this protein?
Uncharacterized protein K205R, pK205R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus K205R family.
Protein: RRF_PHEZH
Sequence: MATTEKPVLSKYRDRMDKAVAALKEEFGSLRTGRASASLLDQIHVDAYGSSMPLTQVAAVSVPEPRMITVNVWDRGMVVSVEKAIRQSDLGLNPVVDGQTLRIPIPPLTEERRKDLAKIAGRYAEQQRVAVRNIRRDANEDLRKAQKDNVISQDEEKRMETEVQKMTDEAIKRIDEALKTKEQEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.