PharMolix/UniProtQA huggingface dataset:
Protein: PYRG_RHILO
Sequence: MARYVFITGGVVSSLGKGIAAAALGALLQARGYRARIKKLDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRSANQQDNITTGRIYKNIIERERRGDYLGATVQVIPHVTDEIKNFVLNGNDDYDFVLCEIGGTVGDIEAMPFLEAIRQLGNDLPRNNAVYVHLTLMPYIPTAGELKTKPTQHSVKELRGIGIAPDILLVRADRAIPKEERRKLSLFCNVRESAVIQALDVPHIYDVPMAYHKEGLDSEVLAAFGIDPAPKPRMEPWQKVSDRIHSPEGEVTIAIVGKYTGLKDAYKSLIEALSHGGLANHVKVKLDWIESEIFEKEDPTPWLEKVHGILVPGGFGERGSEGKILAAKFARERKVPYFGICFGMQMACIEAARSLAGVEHASSTEFGPTEEPVVGLMTEWLKGNMLEKRRETGDLGGTMRLGAYQADLAKGSKIAEIYGDTQISERHRHRYEVNIDYKERLEDCGLVFAGMSPDGVLPETVEYPDHPWFIGVQYHPELKSRPLDPHPLFASFIEAAVEQSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RS7_ACIAD
Sequence: MPRRRVVAAREILPDPKFSSQTIAKFMNHVMQDGKKSVAEGIVYGALERVQEKNKVDPVEFFEATLEKVRPMVEVKARRVGGATYQVPMEVRPSRRTALAMRWLVDAAAKRSEKTMALRLAGELLDAAEGKGAAIKKREDVHRMAEANKAFSHYRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TENB_BEABA
Sequence: MALFQAMSMVAQLGYYEKVAGVLGFLSIALLFWKLNHKPFYPALPLAGEPPQRRWFSLSNRLRYYNDCAALFDEAYHTAYAKKGKAVLVPSMGVHTAMIMPESAMNWAMSQPDDSLSIKKAFSELNQTKYSLGHGRYWEDPWQLDLVKAHLSSILQNLIPQLNEELAAAFSKHLGTDAENWKEIELEVIMRRIIAQATSRFIVGLPLCRDDGYLDLSYKVILGMVTTIWATLPFPDLIRAITGPIASWQTRRNIARIQEYLEPLYQERISILESRDGPESDPEPQDLFMMMLRFAQKKRPDEYANLGIMTRRVCAANFVAMHQSTVSVTNLILNIIGSDAEFNTTATLRDEITQVMRGTDAKSWTKDTFTRMRKCDSVAREAMRLNFPLGTRGSMRAVLKDGLESPEGIKLQKGTTISWLASCAQVDADRFDNPQKFDPFRFSRASKDDDDDGKSTSSHAKDAFVTTSPQYLPFGHGKHACPGRFMVDLMFKILLAQLLTHYDLGWPEDYQGKQPPSVWQGELSEPPPGARILVKRRKV
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of tenellin-type 2-pyridones, iron-chelating compounds involved in iron stress tolerance, competition with the natural competitor fungus Metarhizium robertsii and insect hosts infection (PubMed:17216664, PubMed:19067514, PubMed:20575135, PubMed:34903054).  TenB catalyzes the selective N-hydroxylation of the 2-pyridone nitrogen of yield tellinin and 15-hydroxytellenin (15-HT), respectively (PubMed:19067514, PubMed:34903054).  The pathway begins with the assembly of the polyketide-amino acid backbone by the hybrid PKS-NRPS tenS with the help of the enoyl reductase tenC.  These enzymes catalyze the synthesis of the pyrrolidine-2-dione intermediates pretellinin A, 11-hydropretellenin A, 12-hydropretellenin A, 13-hydropretellenin A, 14-hydropretellenin A, 12-oxopretellenin A and prototellinin D.  The cytochrome P450 monooxygenase tenA then catalyzes an oxidative ring expansion of pretenellin A and 14-hydropretellenin A to form the 2-pyridone core, leading to pretenellin B and pyridovericin, respectively.  The cytochrome P450 monooxygenase tenB is then required for the selective N-hydroxylation of the 2-pyridone nitrogen of yield tellinin and 15-hydroxytellenin (15-HT), respectively.  The UDP-glucosyltransferase GT1 and the methyltransferase MT1, located outside the tenS gene cluster, contribute to the stepwise glycosylation and methylation of 15-HT to obtain the glycoside pyridovericin-N-O-(4-O-methyl-beta-D-glucopyranoside) (PMGP).  Additional related compounds such as 1-O-methyl-15-HT, (8Z)-1-O-methyl-15-HT, and O-methyltenellin A are also produced but the enzymes involved in their biosynthesis have still to be determined (PubMed:34903054).
What are the official names of this protein?
Cytochrome P450 monooxygenase tenB, Tenellin biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DNAK_AGRVS
Sequence: MAKVIGIDLGTTNSCVSVMDGKDAKVIENSEGARTTPSMVAFSDDGERLVGQPAKRQAVTNPTNTLFAVKRLIGRRYEDPTVEKDKGLVPFPIIKGDNGDAWVEAQGKGYSPAQISAMILQKMKETAEAYLGEKVEKAVITVPAYFNDAQRQATKDAGRIAGLEVLRIINEPTAAALAYGLDKTEGKTIAVYDLGGGTFDISVLEIGDGVFEVKSTNGDTFLGGEDFDMRLVEYLAAEFKKEQGIELKNDKLALQRLKEAAEKAKIELSSSQQTEINLPFITADASGPKHLTMKLTRAKFENLVDDLVQRTVAPCKAALKDAGVTAADIDEVVLVGGMSRMPKVQEVVKQLFGKEPHKGVNPDEVVAMGAAIQAGVLQGDVKDVLLLDVTPLSLGIETLGGVFTRLIDRNTTIPTKKSQVFSTADDNQQAVTIRVSQGEREMAQDNKLLGQFDLVGLPPSPRGVPQIEVTFDIDANGIVQVSAKDKGTGKEQQIRIQASGGLSDADIEKMVKDAEANAEADKNRRAVVEAKNQAESLIHSTEKSVKDYGDKVSADDRKAIEDAIAALKSSIETSEPNAEDIQAKTQTLMEVSMKLGQAIYESQQAEGGAEGGPSGHHDDGIVDADYEEVKDDNTKKSA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: BIOD_NEIMA
Sequence: MKGVYFVSGIDTDIGKTIATGVLAKQLLQQGKSVITQKPVQTGCQNIADDIAVHRKIMGIPMQEADKQGLTMPEIFSYPASPHLAARLDGRALDLDKIRTATQQLAAQYEIVLVEGAGGLMVPLTENLLTIDYIRQQGYPVILITSGRLGSINHTLLSFAALKQYGIRLHSLVFNHIHDSRDAHVAQDSLNYLKCRLKDSFPEAEWLELAKTDAV
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PO3F4_XENTR
Sequence: MATAASNPYSILSSSSLVHDSAIMQQGSPFRNPQKLLQSDYLQGVPSNGHPLGHHWVTSLSDANPWSTSLGSSPLDQQDIKPGREDLQLGAIIHHRSPHVTHHSPHTNHPNAWGASPAHNSSLTSNGQPINVYSQSGFTVSGMLDHGGLTPPPPSGTTQSLHPVLREPVDHGDLGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQATICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDPQQHEVYSHSVKTDTSCNEL
What is the function of this protein?
Transcriptional activator.  Induces neural-specific gene expression to act as a key regulator of neural differentiation (By similarity).
What are the official names of this protein?
POU domain, class 3, transcription factor 4.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_SPHAL
Sequence: MADNYTPRMKKLYDDKIVKAMTDKFGYKNAMEVPKIEKITLNMGVGEATQDKKKVEAAAAEMELIAGQKPVVTKAKKSIAQFKLREGMPIGCKVTLRRERMYEFLDRLITIAMPRIRDFRGVSAKSFDGRGNYAMGLKEQIIFPEINYDRIDQVRGMDVIVTTTARTDEEARELLRLFGFPFPIEAQEKEAA
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: Y464_MYCPN
Sequence: MAAVTDNQQSGDNNGLVSLAQRSTTVAVQKSDSSGSQGQGTTDNKFQKYLNTTQALHQMGVIVPSLETWPGKPSTGIATRAAGGVSVQAATRQSTSTNEDLSNVITQLYHTSTSQLAYLNGQIVVMGSDRVPSLWYWVVDERTTSGRATWWAHTELNWGTDKQKQFVENQLGFKDDSNSDSKNSNLKAQGLTQPAYLIAGLDVVADHLVFAAFKAGAVGYDMTTDSNASTKDQVLAWSTTAGLDSDGGYKALVENTAGLNGPINGLFILLDTFAYVTPVSGMKGGSKNTEAVQTKYPVKDDSKASAKIASLINASPLNSYGDDGVTVFDALGLNFNFKLDEARLPSRTDQLLVYGIVNESELKSARENAQSTSDDNSNTKVKWTNTASHYLPVPYYYSANFPEAGNRRRAEQRNGVITIKKAIYPEVRGRQLQNIFDDWKTNKSR
What are the official names of this protein?
Putative MgpC-like protein MPN_464.
What is the protein family that this protein belongs to?
Belongs to the MgpC family.
Protein: NU4C_ACOCL
Sequence: MSYFPWLTIIVVFPISAGLSIFFLPHRGNKVVRWYTICICLLELLLMTYVFCYHFQLNDPLIQLDEDYEWINIFDFHWRPGIDGLSIGPILLTGFITTLATLAAWPVTRDSRLFHFLMLAMYSGQIGLFSSRDLLLFFLMWELELIPVYLLLSMWGGKKRLYSATKFILYTAGGSVFLLMGVPGMGLYGSNEPTLNFETSANQSYPVSLEILFYFGFLIAYAVKLPIIPLHTWLPDTHGEAHYSTCMLLAGILLKMGAYGLVRINMELLPHAHSIFSPWLVLAGTLQIIYAASTSLGQVNLKKRIAYSSVSHMGFTIIGIGSITDTGLNGAILQLLSHGFLGAALFFLAGTSCDRIRLIYLDEMGGISIPMPKIFTMFSSFSMASLALPGMSGFVAEAVVFFGIITSQKFLFLPKILITFVMAIGMILTPIYLLSMLRQIFYGYKLFNMTNSYFMDSGPRELFVSICIFLPVIGIGIYPDFVLSLSVDKVEAILSNYFYR
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4, chloroplastic, NAD(P)H dehydrogenase, chain 4, NADH-plastoquinone oxidoreductase chain 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: Y2119_BRUA4
Sequence: MTEKTPRKPASFTVSQASNRPEAADEAPRRPRAVRDLDVVVAQPDVFALSEEEAAELEILDPSFEAPERKGWSLSRILFGALGILVSFAIGIWTEDLIRALFSRADWLGWTALGVAIIALAAFIAIVVRELVALRRLASVQHLRKDAADAAERDDMAAARKAVDALRSIAAGLPETARGRQLLDGLTDDIIDGRNLIQLAETEILRPLDREARTLILNASKRVSIVTAISPRALVDIGYVIFESARLIRRLSQLYGGRPGTLGFLKLARRVIAHLAVTGTLAMGDSVIQQLVGHGLASRLSAKLGEGVVNGLMTARIGIAAMDVVRPFPFNAEKRPGIGDFIGDLVKINGERPDKKHPGK
What are the official names of this protein?
UPF0283 membrane protein Oant_2119.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y2494_VIBPA
Sequence: MEFEFIRNTLMGEYYVKCSMGHEIVGRWLQEEIGKDPTMIAQVEALIDKAFSLPSQEHTLTGTEISLMIQGDEVLVQENALSHDYDVEMESEFDFYDAESTASCGIEDFVALIEQWKDFLNI
What are the official names of this protein?
UPF0231 protein VP2494.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: RHAM_YERPY
Sequence: MIRKAFVMAVNPDAHAEYQRRHTPIWPELESVLKAHGAHHYSIFLDETRNLLFGVVEIESEERWNAVAQTAECQRWWQHMADVMPSHPDNSPVSQALREVFYLE
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF3_BUCAP
Sequence: MKGGKRIQFTRPNRINNEIRAIKVRLTGVEGDQIGIVNLREALEKAEELGLDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPSTDEGDYQVKLRNLIRFLEDGDKVKITLRFRGREMAHQKIGIDVLNRVKNDLIELAIIESFPSKIEGRQMIMVLAPKKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F1711_XENLA
Sequence: MSGSTAVALLFCVLSCSVWGAGSKASHEHNAAAAAQDVTLKVQVSDVSTHQPIADAVIEIFANQVSAASGTTGADGTALVKLQYKLGSQLIVTATKQAYVPNSAPWRPLRLPVFSSLSLGLLPERSATLMVYDDIVQIVSGFQGSRLQPRVHFQRRALNLPGNATYKDLAAFLTAASTPWEIDSFPYLQGSDGNSTGNNSRFDLTPVTAVSFHLLNSDGTDIPVNGPIYVTVPLPTHSSLKHNAHVPAWRFDQKHGTWLKSSIGIIQQEGSQLTWTYIAPQMGYWVAAMSPSHPDPVVTQDITSYHTIFLLAILGGIAFILLVLLCILLYYCRRKCLKPRQHHRKLQLSTALDCSKKDQATSMSHINLISPIHMEMLSSSGEADMHTPMLKPSYNTSRDFGSREELLSHQEEKSRMSLDNLTPSGTLRQVYNKSLDHILMKSRKSAEISEEYTSTMKDEYRRSYNSVICQPLFESKDKDLLSSTNHVTAGSKPNIQEQMHPVPSAPEPEQLIDRRSNECMMSRSVDHLERPTSFSRPGQLICYNSVDQVNDSVYRNVLPTLVIPAHYVKLPGEHPFVSQQLIVSAEQQFEIERLQAELSHAQQMQPPPLSAQAISQQHLQDGEGVEWSTQNAMMSESVSIPASLNDAAIAQMNGEVQLLTEKALMELGGGRPMPHPRAWFVSLDGRSNAHIRHSYIDLQRAGKNGSNDASLDSGVDMNEPKLGRKLRGEKLSMLHSSMQHPTLQEHQQLNQVNVSDSTAYTQLVYLEDMDQSPSECGTAVCSPEDSRPFIEAPAKKSGSQTPSLQEETIKRTTESSPLPLSSPEHEFNINDDSGEDQGENKKSPWQKREERPLLAFNKK
What is the function of this protein?
May be involved in the regulation of the cytoskeletal dynamics, plays a role in actin stress fiber formation.
What are the official names of this protein?
Protein FAM171A1.
What is the protein family that this protein belongs to?
Belongs to the FAM171 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SSRP_LEGPA
Sequence: MTTKKQPDSTIALNRKAGFDYFIEDQYEAGLVLEGWEVKSLRAGKINLSDSHVIIKYGEAFLLGAQIQPLPTASTHFIPDPVRTRKLLMNKKELNHLIGSVERQGYTIVPLSLYWKKNKIKIKIALAKGKKEHDKRDTIKDREWQRDRSRIMKKNT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: G1PDH_METMA
Sequence: MKLTINKNSAKWMQLPRDVLVGHGVLEEVGDVCRDLKLKGNALIVTGSTTQDVAGKRVSRLLEDAGNSTETVLTCRATMEEVDKLMEKALNTEATFLLGVGSGRSIDLAKLASTRLEIPFISVPTAASHDGIASSRASVIDNGKNASIQAQAPLAVIADTEIISAAPYRFLAAGCGDIISNYTAVLDWELASRLRNEYFGEYAAALSRMAARVVIENADSIKPDHETSARLVVKALVSNGVAMSIAGSSRPASGSEHMFSHALDRIAPKAALHGEQCGVGTIMMMYLHGGNWQEIRDALKKIGAPTNAEELGIEDKYIIEALLQAHSIRPDRYTILGNGLTLSAAEKVARITKVIN
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_UREUR
Sequence: MNLSLREIQKLLVTVAADVARRRLARGLKLNYSEAVALITDHVVEGARDGKLVADLMQSAREVLRVDQVMEGVDTMVGIIQVEVTFPDGTKLVSVHSPIYK
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_BACFN
Sequence: MAVTMADITKLRKMTGAGMMDCKNALTDAEGDFDKAMKIIREKGQAVAAKRSDREASEGCVLVKVEEGFGAIIALKCETDFVAQNADFVKLTQDILDAAVANKCKTLEEVLALPMGDATVAQAVTDRTGITGEKMELDGYMVLEGATIAAYNHMNRNGLCTMVAFNKKVDEQLAKQVAMQVAAMNPIAVDEDGVSEEVKQKEIEVAVEKTKVEQVQKAVEAALKKANINPAHVDSEDHMESNMAKGWITAEDVAKAKEIIATVSAEKAANMPEQMIQNIAKGRLAKFLKEVCLLNQEDIMDAKKTVREVLKEADPELKVVDFKRFTLRAE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKG7_HUMAN
Sequence: MELCRSLALLGGSLGLMFCLIALSTDFWFEAVGPTHSAHSGLWPTGHGDIISGYIHVTQTFSIMAVLWALVSVSFLVLSCFPSLFPPGHGPLVSTTAAFAAAISMVVAMAVYTSERWDQPPHPQIQTFFSWSFYLGWVSAILLLCTGALSLGAHCGGPRPGYETL
What is the function of this protein?
Regulates cytotoxic granule exocytosis in effector lymphocytes, thus acting as a critical mediator of inflammation in a broad range of infectious and non-infectious diseases (By similarity).  Essential for cytotoxic degranulation of natural killer (NK) cells and CD8(+) T-cells and for the activation of CD4(+) T-cells following infection (By similarity).  Plays a critical role in CD8(+) T-cell and NK cell-mediated cytolysis of target cells and contributes to the cytolytic activity via the perforin/granzyme pathway by enhancing exocytosis of LAMP1-carrying lytic granules (By similarity).  Contributes to NK cell-mediated control of cancer metastasis (By similarity).
What are the official names of this protein?
Protein NKG7, G-CSF-induced gene 1 protein, GIG-1 protein, Granule membrane protein of 17 kDa, GMP-17, Natural killer cell protein 7, p15-TIA-1.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytolytic granule membrane; Multi-pass membrane protein.
Protein: CLMP1_CRYNJ
Sequence: MATYLAPPVSSNKENSPAPNIALSDIDAISLSLRTSLSGVTLPAKKKVAALGLGRAPKFTYRRHSNKPYNRSTSITRAKKAAVQTKSVRSKAAVKKSNTRPLPLKLVQRLDVESARLERLRKAVWNPPAPVPGQVRVPLKLPYPRFPSIEYIDNEYLKEIPVQYIFDRMVPLLPSIATITLAYQPYASIPHPDSKILRDTTLAFAIPEVIDGRKPHWAAKARGREPDLALAVAYKSGEGSNGNTVVAVNSLAFATQCAYWPRLLTTSIPIPTPKRPTPSASAVSTSLPAIVETEENVSDASFSSSSSWSDSDSEVEFIDLPRLPRPVKDDKGFLHLPLVELPIPSPSTFPIIHRHLHHPSRALLPDLLGLPEHYTTRSQVLDAISGLSVQQLMDKLTTLQGVWQNLCSLGIGRLGTWRQLGEAWACVVGVIAGQGLLIAGQEEAEVQRTGRKTAAEDVAWEWVRREKAKEQQ
What is the function of this protein?
Required for developmental progression after cells of opposite mating types fuse with one another, essential for processes common to both dikaryotic filament formation and monokaryotic fruiting.  A direct target for transcription factors Sxi1-alpha and Sxi2-a.
What are the official names of this protein?
Clampless protein 1, CLP1.
Protein: HISZ_RUMCH
Sequence: MSRWKIYTPDGVQDILFDECYKKREIEKRIRNTFRSYGYYEIETPTIEFFDVFSSEIEHFPQESMVKFFDQKGRILVLRPDITVPVARITATKNRDVQVPIKYSYIGNVFRFNEVGGGRQNEFTQAGVEMLGDSSSESDAEIIAMAINTLKSVGLKEFKIEIGQVEFFKGLAEEAGFSNEDIDAISKQIDKKDLVGVEEILNRYDISTELREIVLKLTGLFGSVDVIKEFKKASINGRSLKAIENVEEVVSILCDYGLSEYVSIDLGMLKSLNYDTGITFRGFTNGVGFPILSGARYDNLTSSFGKECPATGFSLRINMLMTAMEKAGHTFERPSVDSLVCYEKTNRKRAIEIAEALRKQDMKIETFVLTKGIDQAKKYAASKKIGGIIYIRDNDKITVYDIKNNITEETSFDTLLNNQ
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_TROWT
Sequence: MIRRAPFLILLRFCRMGKMACSGYPPFQGRIVLSEMPAHRLAALIRSKEVSALEVAESFIDNIEASDSRICAFLYTDFSYTRDVARRVDEELKSATKLSPLAGVPIAVKDMILTRDMPTTAGSKILEGWIPPYNATVIERISRARMPILGKTNQDEFGMGSSTEYSAYKTTRNPWDLSRTAGGSGGGSSAAVSASQAPLALGTDTGGSIRLPAHCTGTVGIRPTYGSVSRYGVIALASSFDQVGPCSSNILDAALLHEVIAGYDPADAVSIKDQDLNFSQAAYEGANRGISGVRLGFVNPSNWCNSKITDLFGRTLKSLESEGAVLHEVQFPNFDHAVQAYYLIMQAEASSNLSRYDSIRFGPQEMAASASGTVSKTRSIRFGPEVKRRILLGTHILSAGYYDDFYMSAQKIRLLVKRDFAKIFSLVDVLLLPTAPTPAFKLGEKIDHHTSMYKSDTATTPASLAGLPAGSIPMGVIDGLPVGLQIIAPGQFDSRVYSTGAAIEQIIGDIHAMKNTKHNTGQTA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SQS12_PANGI
Sequence: MGSLGAILKHPDDFYPLLKLKIAARHAEKQIPSEPHWAFCYSMLHKVSRSFGLVIQQLGPQLRDAVCIFYLVLRALDTVEDDTSISTEVKVPIVMAFHCHIYDNDWHFSCGTKEYKVLMDEFHHVSNAFLDLGSSYKEAIEDITMRMGAGMAKFICKEVETIDDYDEYCHYVAGLVGLGLSKLFHASGAEDLATDSLSNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPRQIWSKYVDKLEDLKYEENSAKAVQCLNDMVTDALVHAEDCLKYMSDLRGPAIFRFCAIPQIMAIGTLALCFNNTQVFRGVVKMRRGLTAKVIDQTKTMSDVYGAFFDFSCLLKSKVDNNDPNATKTLSRLEAIQKTCKESGTLSKRKSYIIESESGHNSALIAIIFIILAILYAYLSSNLLPNKQ
What is the function of this protein?
Component of the triterpene saponins (e. g.  ginsenosides or panaxosides) and phytosterols biosynthetic pathways (PubMed:27746309, PubMed:29378087).  Catalyzes the biosynthesis of squalene (By similarity).
What are the official names of this protein?
Squalene synthase 12, PgSS12, SQS 12, FPP:FPP farnesyltransferase SS12, Farnesyl-diphosphate farnesyltransferase SS12.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: IPGC_SHIDY
Sequence: MSLNITENESISTAVIDAINSGATLKDINAIPDDMMDDIYSYAYDFYNKGRIEEAEVFFRFLCIYDFYNVDYIMGLAAIYQIKEQFQQAADLYAVAFALGKNDYTPVFHTGQCQLRLKAPLKAKECFELVIQHSNDEKLKIKAQSYLDAIQDIKE
What is the function of this protein?
Assists the correct folding of nascent IpaB.  Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG (By similarity).
What are the official names of this protein?
Chaperone protein IpgC.
What is the protein family that this protein belongs to?
Belongs to the LcrH/SycD chaperone family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSF3_SHEEP
Sequence: TPLGPARSLPQSFLLKCLEQVRKIQADGAELQERLCATHKLCHPEELVLLGHSLGIPQAPLSSCSSQSLQLTSCLDQLHGGLFLYQGLLQALAGISPELAPTLDTLQLDVTDFATNIWLQMEDLGVAPAVQPTQGTMPTFTSAFQRRAGGVLVASQLQRFLGLAYRGLRYLAEP
What is the function of this protein?
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.  This CSF induces granulocytes (By similarity).
What are the official names of this protein?
Granulocyte colony-stimulating factor, G-CSF.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BBCI_BAUBA
Sequence: SVILDTKGEPVSNAADAYYLVPVSHGEGGLALAKVGNEAEPKAVVLDPHHRPGLTVRFETPLAIAIITESFFLNIKFVPSSSDSEVWDVSKQYPIGLAVKVTDTKSFVGPFRVEKEGEGYKIVYYPDRGQTGLDIGLVHRNDKYYLAATEGEPFVFKIRKATYE
What is the function of this protein?
Inhibits T. cruzi cruzipain.
What are the official names of this protein?
Kunitz-type proteinase inhibitor BbCI.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I3 (leguminous Kunitz-type inhibitor) family.
What are the subcellular locations of this protein?
Secreted.