PharMolix/UniProtQA huggingface dataset:
Protein: SYFA_DESAP
Sequence: MREKLAQVVEEAEKALAGASTAEVVEEVRIRYLGKKGVLTQVLRSMGSLPAAERPVVGKLANEMKVRLEQALASRSALLKQEEKAARLAAERIDVTLPGVLPHLGSMHPLTMVRTEIENIFLGLGFQIVEGPEVELEYYNFEALNFPKDHPARDMQDTFFINDEVLLRTHTSPVQVRTFEKTAPRVPVRIIAPGKVYREDDDATHSPMFNQVEGFAVDTRITLGDLKGTLVYFVREMFGERRMRFRPSFFPFTEPSAEVDISCVICGGGGCRVCSHTGWLEILGAGMIHPRVLEVSGYDAEKVSGFAFGMGIERVAMLKYGIDNIRLFFDNDLRFLNQF
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_BACC4
Sequence: MSLFDHSVSELHKKLNNKEISVTDLVEESYKRIADVEDNVKAFLTLDEENARAKAKELDAKIGAEDNGLLFGMPIGVKDNIVTNGLRTTCASKMLANFDPIYDATVVQKLKAADTITIGKLNMDEFAMGSSNENSGFYATKNPWNLDYVPGGSSGGSAAAVAAGEVLFSLGSDTGGSIRQPAAYCGVVGLKPTYGRVSRYGLVAFASSLDQIGPITRTVEDNAYLLQAISGIDRMDATSANVEVGNYLAGLTGDVKGLRIAVPKEYLGEGVGEEARESVLAALKVLEGMGATWEEVSLPHSKYALATYYLLSSSEASANLSRFDGVRYGVRSDNVNNLLDLYKNTRSEGFGDEVKRRIMLGTFALSSGYYDAYYKKAQQVRTLIKNDFENVFANYDVIIGPTTPTPAFKVGEKVDDPMTMYANDILTIPVNLAGVPAISVPCGFGANNMPLGLQIIGKHFDEATIYRVAHAFEQATDYHTKKASL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: FTSH_CALBD
Sequence: MRNLFKTATIYILIALVILLLVDIFSGGLSYNQFFSNLSERREVIYSELINDINDGKVTRIVLSYNNVSGQYADGTKFDNVFVPSPDKFLDQIQPAIQAKKIQIVTKEPPQVPWWLSTFLPMLIFAGLMIFVWIFMLQQTQGGGSKIMSFTKSRAKTIQDLKKKVTFADVAGADEEKEELKEVIDFLKNPRKYIELGARIPKGILLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGAARVRDLFDQAKRNAPCVVFIDEIDAVGRHRGAGLGGGHDEREQTLNQLLVEMDGFGTNEGIIVMAATNRPDILDPALLRPGRFDRQIVVNVPDAKAREEILKVHARNKPLGEDVDLSQIAKITAGFTGADLENLLNEAALLAARKGKRQINMEEVQEAVAKVLMGPEKRSRVYTEKEKKLTAYHEAGHAIVRTMIPDSEPVHEVSIIPRGYAGGYTMYLPKEDKFYASKSDMMREIVTLLGGRVAEKLVLEDVSTGAASDIKRATKIARDMVTKYGMSDKLGPMTFGTEQEEVFLGRDLALARNYSEEVAAEIDREIKSIIEEAYKKAEEILKQNIDKLHKVANALLEKEKLTGEEFRKLVFEDAQPQLV
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: AQPM_METTM
Sequence: MVSLTKRCIAEFIGTFILVFFGAGSAAVTLMIASGGTSPNPFNIGIGLLGGLGDWVAIGLAFGFAIAASIYALGNISGCHINPAVTIGLWSVKKFPGREVVPYIIAQLLGAAFGSFIFLQCAGIGAATVGGLGATAPFPGISYWQAMLAEVVGTFLLMITIMGIAVDERAPKGFAGIIIGLTVAGIITTLGNISGSSLNPARTFGPYLNDMIFAGTNLWNYYPIYVIGPIVGAVLAALTYQYLTSE
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.  Exhibits also a transient but reproducible increase in the initial glycerol flux.
What are the official names of this protein?
Aquaporin AqpM.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SODC_HUMAN
Sequence: MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, hSod1.
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus. Note=Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria.
Protein: PHS_BRUSI
Sequence: MARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHPEWFNAYNRVDVTLATHSENGVTELDIKMARKMNAIAG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: COX1_ORTHI
Sequence: MFINRWLFSTNHKDIGTLYMIFGAWAGMVGTGLSILIRAELGQPGSLLGDDQIYNVVVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFFLLLASSMVEAGAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAITQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGMDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTIGGLTGIVLSNSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNDTWAKIHFTIMFVGVNMTFFPQHFLGLAGMPRRYSDYPDAYTTWNTISSMGSFISLTAVILMVFMIWEAFASKRVVKSVSLTSTNLEWIHGCPPPFHTFEEPAFIKSSH
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSCL_LEVBA
Sequence: MLKEFKEFIARGNVMDLAVGVIVGAAFTAIVNSLVTNIINPLLGIFVGSIDFSNLVFTVGSAHFRYGAFINSVINFLIIAFVVFLLIKLINKLIAKPAEEPEEAVPSQEEKYLQEIVELLKQDKIEH
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PKRI1_BOVIN
Sequence: MASSAASSVRPPRPKKEPQALIIPKNAAEEQKLKLERLMKNPDKAVPIPEKMSEWAPRPPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLEAEFQKRLERNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQSEASSETQEQPSSGSEEASGTEDEEEDAPSFITGR
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (By similarity).  Binds double-stranded RNA.  Inhibits EIF2AK2 kinase activity (By similarity).
What are the official names of this protein?
PRKR-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the PRKRIP1 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus.
Protein: RR15_PINTH
Sequence: MINNLSISSSLIPDKQRGSVESQVFYLTNRVLRLTQHLQLHGRDYSSQRGLWKILSKRKQLLVYLSKRDKLRYDDLIGQLGIRGLKTR
What are the official names of this protein?
30S ribosomal protein S15, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MEND_MICAN
Sequence: MSIDFRNLNTLWGSILVETLARLGLKIGVVSPGSRSTPLTIALARHPQIEAIPILDERSAAFFALGLAKQLYQPVVLVCTSGTATANFYPAVIEAKESHVPLLILTADRPPELRHAHAGQTIDQVKLYGNYPNWQAEISCPSANIERLRYLRQTIIHAWWRCLDPVPGVVHLNLPFRDPLAPTPDLEINNLEANFDQEAFFSHISRQNIAINHSILQINSLPSKGIIIAGLASPQNPESYCQAIADLARSQQYPILAEALSPLRNYAGLNPHLITTYDLLLRNPALRTQLTPDVVLQIGELPTSKELRTWLEEIDCPRWIIDPHPDNYDPLQGKTGHLRVNIEQLGDLFPDKTDNNREYRQLWQKFDQQARLTIDRLLAAETKLIEGKIPWLLSQYLPPRTPIFISNSMPVRYAEFFNPPSDRQIRPYFNRGANGIDGNLSTAIGIAYKNVPSLLLTGDLALLHDTNGFLIKKYFVGSLTIILINNKGGGIFQMLPIAKFDPPFEEFFATPQNIDFCQLCRTYGIDYHLISDWTDFEQKIAVLPESGIRLLEISCDRAFNTQWFLSNYV
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: H2B_DROSE
Sequence: MPPKTSGKAAKKAGKAQKNITKNDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DAPA_YERP3
Sequence: MFTGSIVALITPMDDNGDVDRASLKSLIDYHVASGTAAIVSVGTTGESATLNHDEHVDVVMQTLELADGRIPVIAGTGANSTSEAISLTQRFNDTGVVGCLTVTPYYNRPMQEGLYQHFKAIAESTDLPQILYNVPSRTGCDMLPPTIARLAKIKNIVAVKEATGNLSRVSQIQVLVDDEDFILLSGDDASGLDFMQLGGKGVISVTANIAAREMVELCALAAQGNFAEGRRLNQRLMPLHQHLFVEANPIPVKWAAKRLGLMANDTMRLPMTPLTDPAKRIVEDALKSAGLL
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_STRPI
Sequence: MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEAAFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RISB_NEIG2
Sequence: MNTIAPNLDGKHLRIGIVQARFTNEIGSQMLKVCCRTLQELGVADENITVATVPGALEIPIALMNFASSEKFDALIAIGVVIRGETYHFELVANESGAGIGRVALDYNIPIANAVLTTENDAQAIERIGEKASDAAKVAVECANLVNLLLEEQFEDEE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PDXJ_RHIME
Sequence: MPAKLSVNLNAIAMLRNRRDLPWPSVTGLGRTALQAGASGLTVHPRPDQRHIRFSDLQPIRDLIDDEFPAAEFNMEGFPNEAFLELVERHEPEQVTLVPDDPAQATSDHGWDFRKSHNLLGNVVGRLKKRGFRVSLFADGIPDPEALKLAKETGADRIELYTGPYGGCYDDPEKAERIAIELGRTAEIAIGLGLAVNAGHDLTVANLPLLVEHIPELAEVSIGHGLTADALEYGMAETVRRFRRACGETA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSD_CITK8
Sequence: MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMMYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALDKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIEIVPLYLAAERPVLERDGMLMMIDDDRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESSAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: NAATB_HORVU
Sequence: MATVRQSDGVAANGLAVAAAANGKSNGHGVAAAVNGKSNGHGVDADANGKSNGHGVAADANGKSNGHAEATANGHGEATANGKTNGHRESNGHAEAADANGESNEHAEDSAANGESNGHAAAAAEEEEAVEWNFAGAKDGVLAATGANMSIRAIRYKISASVQEKGPRPVLPLAHGDPSVFPAFRTAVEAEDAVAAAVRTGQFNCYPAGVGLPAARSAVAEHLSQGVPYMLSADDVFLTAGGTQAIEVIIPVLAQTAGANILLPRPGYPNYEARAAFNRLEVRHFDLIPDKGWEIDIDSLESIADKNTTAMVIINPNNPCGSVYSYDHLSKVAEVAKRLGILVIADEVYGKLVLGSAPFIPMGVFGHITPVLSIGSLSKSWIVPGWRLGWVAVYDPRKILQETKISTSITNYLNVSTDPATFIQAALPQILENTKEDFFKAIIGLLKESSEICYKQIKENKYITCPHKPEGSMFVMVKLNLHLLEEIDDDIDFCCKLAKEESVILCPGSVLGMANWVRITFACVPSSLQDGLGRIKSFCQRNKKRNSSDDC
What is the function of this protein?
Involved in biosynthesis of mugineic acid family phytosiderophores.
What are the official names of this protein?
Nicotianamine aminotransferase B.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: Y2623_MYCTO
Sequence: MSSGNSSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSPEVATWLEVPLPPGVLRWQQDHGRHLIDDALKVVEQASLRAGPPTVHSEIVPAAAVPTLVDMSKDAVLMVVGCLGSGRWPGRLLGSVSSGLLRHAHCPVVIIHDEDSVMPHPQQAPVLVGVDGSSASELATAIAFDEASRRNVDLVALHAWSDVDVSEWPGIDWPATQSMAEQVLAERLAGWQERYPNVAITRVVVRDQPARQLVQRSEEAQLVVVGSRGRGGYAGMLVGSVGETVAQLARTPVIVARESLT
What is the function of this protein?
May play a role in the establishment of a persistent infection (latency) in the host.
What are the official names of this protein?
Universal stress protein MT2698.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: Y591_DESPS
Sequence: MKFSVKNILEMEVCLALGCTEPVAIALGAAAAATLLPGLKFDHIHLIIDPNIYKNGLAVVIPGSGGLTGLDTASALGAFGGDAYGKLEVLSSLSPEMVARASAFLAEGRVKVDLREESGLYVKTTISGGGHVAESLITDVHTNIVSLMLDGEEVADPRLVATEAMSTGNKLAELEEWLRSLTLEDILDLTNELDEADLDFLEEGVQHNLRLAEYGLKHGSGLGIGKDIDRLLKQKLLVKDMTTSARMLTSAAADARMDGVNLPAMSSGGSGNHGLTAILPIWAIKDFIETDRESVLRAIGLSHIITAYIKAHTGRLSAVCGCSVAAGAGATAGITYLVGGDLQQVEGAIKNILEDLAGVICDGAKAGCAIKLNTAAGAAVQAALFSLQGVSVKDTDGIIGDSTRQTVQNIGDLSNYGMVATDKTILKIMRAKHKKG
What are the official names of this protein?
UPF0597 protein DP0591.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: ERA_EHRRG
Sequence: MNHVGRKCSMSAIVGTTNAGKSTLVNVLVGQKVAAVTPKVQTTRVRMHAVSNHENVQLIFIDTPGIFSPKTKLEKFLVKHAWMSLKGIENVIVLVDVKNYLNQHLKKIIDRIKHSNLNAILVLNKIDIVHQSIVSEVIEYMYSLYKFSKAFTISALYGIGIDKLVDYLCETSPYGPWLYNDDQISDAPLKFFMAEITREKLFITLRHELPYSLSVVTELVEEKEDNSLIIKQVIYVTKDSHKTIILGKKGEMVKKISMESKSDLENILQVKVHLFLFVKVREFWQNHLNECVGYAE
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: FANE_ECOLX
Sequence: MNKFISIIALCVFSSYANAAFTLNSTRYIYNEGQQSVSVNIHNESEHKYGGQVWIDNIDKNGEVVFFSPSPMVFKLNPKQKQIVRIVNINDNLPKDRESIFWLNVQEIPPAPKGDGGSLSLAINNRVKLIYRPIALKNGRDEAENNIKLINSGTDSCLENTTPYYFAISDVKINGKSIDLNSDAKNKMGVFSPFSKVCLGNVNTSGNITVTAFNDYGVATSYTVQRSK
What is the function of this protein?
Mediates assembly of pili by forming soluble multimeric complexes with pili subunits as an intermediate step in the assembly process.  This protein is involved in K99 pili assembly.
What are the official names of this protein?
Chaperone protein FanE.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MSRB_STAES
Sequence: MIKKNKEELNDMEYLVTQENGTEPPFQNEYWNHFEKGIYVDKLSGKPLFTSEDKFESNCGWPSFSKALNDDEIVELVDKSFGMIRTEVRSEKANSHLGHVFNDGPKEKGGLRYCINSAAIQFIPYDKLEELGYGDLIKHFKK
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: DTD_SALPC
Sequence: MIALIQRVTRASVTVEDEVTGEIGLGLLVLLGVEKEDDEQKANRLCERVLGYRIFSDADGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSGGAAPDRAQALYEYFVERCRQQAINTQTGRFAADMQVELVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_PSEAB
Sequence: MKFVDEVSIHVKAGDGGNGLMSFRREKFIEKGGPNGGDGGDGGSIYLEADVNLNTLVDYRYTRRFDAQRGENGGSKDCTGAKGDDLILPVPVGTTVIDANTQEIIGDLTEPGQRLMVAQGGWHGLGNTRFKSSTNRAPRQTTPGKPGEARDLKLELKVLADVGLLGLPNAGKSTFIRAVSAAKPKVADYPFTTLVPNLGVVSVGRYKSFVVADIPGLIEGAAEGAGLGIRFLKHLARTRILLHLVDMAPLDESDPADAAEVIVRELGRFSPALTERERWLVLNKMDQILDPAEREARKQAVIERLGWEGPVYVISALERDGTEALSQDIMRYLDERTLRLEEDPQYAEELAELDRRIEDEARARLQALDDARALRRSGLKNAGAVDDDDFDDEEDDGDGPEIFYVP
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control (By similarity).  Overexpression increases bacterial persistence in both stationary phase and biofilms in response to a number of antibiotics (PubMed:26051177).
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_MESH7
Sequence: MESKLSFESFFYNESKKAYFQKLMEKLDEEYEKYQVFPNKKDLFRAIELTNFATLKIVIIGQDPYHRKGQADGLAFSTRTKILPPSLRNLFLEIKNAYPNFSKENGNLENWAKQGVLLLNHVLTVRKSSPNSHKNIGWEVFSSNLINFIVKNKVDIVFLLLGKKAKLAVKNINLEKQKVFAYSHPSPFSFAKSLKNSMVFRKINDFLKEKKRLEINWNL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS23B_NAUCC
Sequence: MGKGKPRGLNSARKLRVHRRNNRWAENNYKKRLLGTAFKSSPFGGSSHAKGIVLEKLGIESKQPNSAIRKCVRVQLIKNGKKVTAFVPNDGCLNFVDENDEVLLAGFGRKGKAKGDIPGVRFKVVKVSGVSLLALWKEKKEKPRS
What are the official names of this protein?
40S ribosomal protein S23-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SMPX_MOUSE
Sequence: MSKQPISNVRAIQANINIPMGAFRPGAGQPPRRKESTPETEEGAPTTSEEKKPIPGMKKFPGPVVNLSEIQNVKSELKFVPKGEQ
What is the function of this protein?
Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.
What are the official names of this protein?
Small muscular protein, Stretch-responsive skeletal muscle protein, Chisel protein.
What is the protein family that this protein belongs to?
Belongs to the SMPX family.
Protein: GUCNB_HUMAN
Sequence: MGRKEHESPSQPHMCGWEDSQKPSVPSHGPKTPSCKGVKAPHSSRPRAWKQDLEQSLAAAYVPVVVDSKGQNPDKLRFNFYTSQYSNSLNPFYTLQKPTCGYLYRRDTDHTRKRFDVPPANLVLWRS
What are the official names of this protein?
Putative uncharacterized protein GUCA1ANB, GUCA1A neighbor.
Protein: HELS_PYRFU
Sequence: MRVDELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHRILTQGGKAVYIVPLKALAEEKFQEFQDWEKIGLRVAMATGDYDSKDEWLGKYDIIIATAEKFDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILAHMLGKAQIIGLSATIGNPEELAEWLNAELIVSDWRPVKLRRGVFYQGFVTWEDGSIDRFSSWEELVYDAIRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEKLAKAIRGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWRYSDFGMERIPIIEVHQMLGRAGRPKYDEVGEGIIVSTSDDPREVMNHYIFGKPEKLFSQLSNESNLRSQVLALIATFGYSTVEEILKFISNTFYAYQRKDTYSLEEKIRNILYFLLENEFIEISLEDKIRPLSLGIRTAKLYIDPYTAKMFKDKMEEVVKDPNPIGIFHLISLTPDITPFNYSKREFERLEEEYYEFKDRLYFDDPYISGYDPYLERKFFRAFKTALVLLAWINEVPEGEIVEKYSVEPGDIYRIVETAEWLVYSLKEIAKVLGAYEIVDYLETLRVRVKYGIREELIPLMQLPLVGRRRARALYNSGFRSIEDISQARPEELLKIEGIGVKTVEAIFKFLGKNVKISEKPRKSTLDYFLKS
What is the function of this protein?
DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.  Unwinds the lagging strand from forked DNA structures in a 3'-5' direction.  PCNA, the DNA polymerase sliding clamp subunit, stimulates the helicase activity, and may alter substrate specificity.  Unwinds branched DNA (Holliday junctions) in an ATP-dependent fashion; ss- and dsDNA stimulate ATPase to the greatest extent, although it preferentially binds DNA with a single-stranded region.  Processes a RecA-mediated recombination intermediate between gapped circular and homologous linear dsDNA.
What are the official names of this protein?
ATP-dependent DNA helicase Hel308, ATP-dependent Holliday junction unwindase Hjm, Holliday junction migration DNA helicase.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Hel308 subfamily.