PharMolix/UniProtQA huggingface dataset:
Protein: AK_YEAST
Sequence: MPMDFQPTSSHSNWVVQKFGGTSVGKFPVQIVDDIVKHYSKPDGPNNNVAVVCSARSSYTKAEGTTSRLLKCCDLASQESEFQDIIEVIRQDHIDNADRFILNPALQAKLVDDTNKELELVKKYLNASKVLGEVSSRTVDLVMSCGEKLSCLFMTALCNDRGCKAKYVDLSHIVPSDFSASALDNSFYTFLVQALKEKLAPFVSAKERIVPVFTGFFGLVPTGLLNGVGRGYTDLCAALIAVAVNADELQVWKEVDGIFTADPRKVPEARLLDSVTPEEASELTYYGSEVIHPFTMEQVIRAKIPIRIKNVQNPLGNGTIIYPDNVAKKGESTPPHPPENLSSSFYEKRKRGATAITTKNDIFVINIHSNKKTLSHGFLAQIFTILDKYKLVVDLISTSEVHVSMALPIPDADSLKSLRQAEEKLRILGSVDITKKLSIVSLVGKHMKQYIGIAGTMFTTLAEEGINIEMISQGANEINISCVINESDSIKALQCIHAKLLSERTNTSNQFEHAIDERLEQLKRLGI
What are the official names of this protein?
Aspartokinase, Aspartate kinase.
What is the protein family that this protein belongs to?
Belongs to the aspartokinase family.
Protein: PYRD_SALPB
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPLEALVRQKVPTKPVTCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSLEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHFDGILGINIGKNKDTPVENGKDDYLICMEKVYAYAGYIAINISSPNTPGLRTLQYGDALDDLLTAIKNKQNDLQAIHHKYVPVAVKIAPDLCEEELIQVADSLLRHNIDGVIATNTTLDRSLVQGMKNCQQTGGLSGRPLQLKSTEIIRRLSQELKGQLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: FGF2_RABIT
Sequence: PALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGSKTGPGQKAI
What is the function of this protein?
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity).  Also acts as an integrin ligand which is required for FGF2 signaling (By similarity).  Binds to integrin ITGAV:ITGB3 (By similarity).  Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity).  Functions as a potent mitogen in vitro (By similarity).  Can induce angiogenesis (By similarity).  Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
What are the official names of this protein?
Fibroblast growth factor 2, FGF-2, Basic fibroblast growth factor, bFGF, Heparin-binding growth factor 2, HBGF-2.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted. Nucleus. Note=Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism (By similarity). Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane (By similarity). Binding of exogenous FGF2 to FGFR facilitates endocytosis followed by translocation of FGF2 across endosomal membrane into the cytosol (By similarity). Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as CEP57 (By similarity).
Protein: RSGA_XANC8
Sequence: MSDTSPNYHTLQSIGWPWPGPPEDPAWQAIFAAHPQALPARVVEQHRTGYVVADTPEASLKAESLPEWQRPRFPSHERAAVGDWVLMEGKRIVALLPRRTSIKRGAAGEHYHQQVIAANIDTVFIVCGLDADFNPRRIERYLLLVGGGGAEPVVVLTKADQTEYAEDALAVLEELEAQNIALRAVNAKDPESVAALRPWLGDGRTAVLVGSSGAGKSTLTNTLLGTQKMKTNAVRENDSRGRHTTTHRALIPLPSGACLIDTPGMRELKPTGEEDLAEGGFSDVEALAAQCRFNDCAHIAEPGCAVRAAIEADQLDPERVANYMKLRVEVASAAEKLATRVAQNNRGKGSGKRPASVDRPGRR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_BLOFL
Sequence: MAHKKAGGSTRNGRDSRGKRLGVKHFGGEIISAGTIIVRQRGNKFHPGKYVGCGRDHTLFALQSGKLLFEKKGKLQRRLVSIIVE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RS13_LEPCP
Sequence: MARIAGINIPPHKHAEIGLTSIYGVGRTTAQKICEACGIAYNKKVKDLDDSDLEKIREEVGRLTIEGDLRREISINIKRLMDLGCYRGFRHRRGLPVRGQRTRTNSRTRKGPKKGAAALKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CH60_TOLAT
Sequence: MAAKDVKFGSDARIKMLEGVNVLANAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELEDKFQNMGAQMVKEVASQANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVLAAVEELKTLSVPCADTKAIAQVGTISANSDENVGKLIAEAMDKVGRDGVITVEDGQGLQDELAVVEGMQFDRGYLSPYFINKQDTASVELDDPFILLVDKKVSNIREMLSVLEGVAKAGKPLVIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAILTAGTVISEEIGMELEKATLEELGRAKRIVITKENTTIIDGVGEAATIEARIAQIRQQIEESSSDYDKEKLQERVAKLAGGVAVIKVGATTEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRAAAKLADLKGDNEDQTVGIRVALRAMESPLRQIVDNAGEEPSVVANRVREGEGNFGYNAATEVYGDMLEMGILDPTKVTRLALQFAASVAGLMITTECMITDAPKKDAPAMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y226_ARCFU
Sequence: MECLDLLFRRVSIRKFTQDDVDDEILMKILEAGNAAPSAGNLQARDFVVIRNPETKKRLAMAALKQMFIAEAPVVIVVCANYPRSMRVYGERGRLYAEQDATAAIENILLAVTALNLGAVWVGAFDEEQVSEILELPEYVRPMAIIPIGHPAENPSPRNRYPVSMLTHFEKW
What are the official names of this protein?
Putative NADH dehydrogenase/NAD(P)H nitroreductase AF_0226.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: KLK9_HUMAN
Sequence: MKLGLLCALLSLLAGHGWADTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIMEN
What are the official names of this protein?
Kallikrein-9, Kallikrein-like protein 3, KLK-L3.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YCIB_SHEON
Sequence: MKQLLDFLPLVIFFAVYKFFDIYIASGALIAATALQLVVTYALYKKLEKMHLITFAMVTVFGTLTLVFHDDAFIKWKVTIIYALFALALGVSQLLNKSILKSMLGKEMKVADNIWAHVTWYWVSFFAICGLVNIYVAFSLPLETWVNFKVFGLTALTLINTVITVFYLYKHLPEDQRKELK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRCB_BORPD
Sequence: MTQTLIPLNFLAVAIGAALGACARWLAGLWLNSSAWPWGTLLVNLAGGYLIGLALAVLLAHPEWPQWIRLAAVTGFLGGLTTFSTFSAETVGMLERGAYATALGYAALSLVGSLALTALGLASAHALR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPRT_YERE8
Sequence: MSSLRIPIALQQAVMRCLRHKLQLANQHLGTDYPEPKINYHQRGTSAGSAYLQSFEIRLNPVLLLENQQPFIDEVVPHELAHLLVYRQFGRVPPHGKEWRWMMEHVLQVPASRTHQFAVTSVRSKTFNYQCKCQQHALTIRRHNKVQRGESEYRCRECGEKLQFVAKKTC
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEXA_METS4
Sequence: MLTRKQLDLLRFIQQRMRETGVPPSFDEMKDALDLKSKSGIHRLITALEERGFLRRLPNRARAIEVIRIPEAVASGPAEVVRFTPSVVEGGRSSAPVKPAPLPTALVSDESGHAVSIPVMGRIAAGTPISAIQSQSRSVAMSPDFLAGGEHYALEVRGDSMIEAGILDGDLVVIRRQDTANTGDIVVALIDDEEATLKRLRRRGSSIALEAANPAYETRVLGPDRVRIQGRLVSLIRKY
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SYS_RHIL3
Sequence: MLDIKWIRENPEALDAALAKRGAEPLAQSLVALDEKRRSAVQKAQDLLSRRNLASKEIGAAMAQKNSELAEKLKAEVSELKTLLPAIEEEDRQLTAELNDALSRIPNIPFDDVPVGKDEHDNIVTRTVGEKPRWNHAPKEHFEIGEALGYMDFERAAKLSGSRFTVLTGPLARLERALGQFMIDLHTSEHGYIEVSSPLMVRDEAVYGTAQLPKFAEDLFRTTDGRWLIPTAEVTLTNLVREEILDQEKLPLRFTALTPSFRSEAGSAGRDTRGMLRQHQFWKCELVSITDAESAVAEHERMTACAEEVLKRLGLHFRTMTLCTGDMGFGSRKTYDLEVWLPGQNAFREISSCSVCGDFQGRRMNARYRGKDDKSNKFVHTLNGSGTAVGRCLIAVLENYLNEDGSVTIPDVLLPYMGGLTKIERAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4K2A_HUMAN
Sequence: MDETSPLVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAGSGPSPPGSPGHDRERQPLLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRERNEFPEDPEFEAVVRQAELAIERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDCPMDSSSSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
What is the function of this protein?
Membrane-bound phosphatidylinositol-4 kinase (PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is required for prolonged survival of neurons.  Besides, phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P) is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).
What are the official names of this protein?
Phosphatidylinositol 4-kinase type 2-alpha, Phosphatidylinositol 4-kinase type II-alpha.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Membrane raft. Cell projection, dendrite. Presynaptic cell membrane. Synapse, synaptosome. Mitochondrion. Endosome. Cytoplasmic vesicle. Membrane; Lipid-anchor. Cell membrane. Perikaryon. Cell projection, neuron projection. Note=Found in subdomains of the plasma membrane termed non-caveolar membrane rafts. Transported from neuronal cell body to neuron projections and neurite tips in a BLOC-1- and AP-3- complexes-dependent manner.
Protein: FTSH_PARUW
Sequence: MSDDNKQDFKKGISNSFVWFLMAAFLFALMVQNFIDTKFAKVSFSYQLEHLVNLQLLQPEDSRKIALNDNLVTFSGKFRDRLTEEGKTRYKYLELLDTNHELKAEQARVKDEIKTLKTKVFDSASLFLQLSGLSIPKGGYVVVDDMYNTPEEDQSVVIKDLPKSAVESLVSLEKEYEAARQNPTAESLKNLGNLINELLRNLRSPALGIGSETIKQSLKGIDKEVADSGATSLSEQLAAYGHALVNLKAIIDELNHEEDHIRLAKLRSVRNYKETLDEYNQINTRLDDNQIQLDKARQSVSNVIWYFNNQELSTKALEKQDPEVYNQWFSKAKEEWANFSHNRGGIFRAPDQPLNAVLEKTFKSEEPSPNYFSYLFTLLPVLLVILVLYMLFARQMKGMGNTAMNFGKSPARLLNKGDNKITFKDVAGVDEALEELQEIVEFLKNPQKFTSLGGKIPKGVLCIGPPGTGKTLIAKAVAGEADRPFFSISGSDFVEMFVGVGASRIRDLFEQAKKAAPCIIFMDEIDAVGRHRGVGMGGGHDEREQTLNQLLVEMDGFDTNEGVILMAATNRPDVLDKALLRPGRFDRRVIIGLPDIKGRYDILKVHARRIKMDPSIDLMAIARSTPGSSGADLANILNESALLAARKGRTAVTAQETIEARDKVLYGKERRSLEIDENEKRTTAYHESGHTVVGLIVKSGDPVDKVTIIPRGMSLGATMFLPKKNRVSYWKQELHDQLAVLMGGRVAEEIFVGDVSSGAQQDIERATQLARSMVCKWGMSDKLGAVAYDERSEGGGQYGFGDHHEKTYSDETAQAIDSEVRRILDEALAIARKIILDYKEQVELLTLMLIEFETLDSEDIQEIVVKNNWDAVRKRERLKRAADLHKKEAATPPPPPPREVDISSSGTIPNTLGLSS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins (By similarity).
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: KPRS2_ARATH
Sequence: MASLALTSPPSVKIPSYLSSSSSSLFSRSSISFRTTESRSRICVSGYAKCNLPKALNGNARVPIINETTIPKFFDSSRLEKSVSRNNTKLKLFSGTANPALSQEIAWYMGLELGKVSIKRFADGEIYVQLKESVRGCDVFLVQPTCTPTNENLMELLIMVDACRRASAKKVTAVIPYFGYARADRKTQGRESIAAKLVANLITEAGADRVLACDLHSGQSMGYFDIPVDHVYCQPVILDYLASKSISSEDLVVVSPDVGGVARARAFAKKLSDAPLAIVDKRRHGHNVAEVMNLIGDVKGKVAVMVDDIIDTAGTIVKGAALLHEEGAREVYACCTHAVFSPPAIERLSSGLLQEVIVTNTLPVAEKNYFPQLTILSVANLLGETIWRVHDDSSVSSIFL
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase 2, chloroplastic, PRS II, Phosphoribosyl pyrophosphate synthase 2.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KC1G_CAEEL
Sequence: MTNTRGSNSATSASTTNSQGVLMVGPNFKVGKKIGCGNFGELRLGKNLYNNEHVAIKLEPMKSKAPQLHLEYRFYKLLGQAEGLPQVHYFGPCGKYNALVMELLGHSLEDLFDLCDRHFSLKTVAMVAMQLIRRIEYVHTKHLIYRDVKPENFLIGRYSTRKQHVLHIIDFGLAKEYIDCDTGKHIAYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRQTAVEVLCEGFPDEFAQYLRYARRLDFFETPDYDFCYNLFKSVLDRLGATYDYEFDWTPKLNNVSTPSGSLHTSESKDVKRTDRGELKVSQAAAHAQFGSTQVINSNAGEVVEESRNTEGRTAAGDNSSGEVKCCCFRRRRRKHNNATPATQK
What is the function of this protein?
Involved in the asymmetric cell division of the embryo downstream of par-2 and par-3 by regulating the asymmetric cortical distribution of pkk-1, a phosphatidylinositol 4,5-bisphosphate-producing enzyme, which in turn regulates the asymmetrical distribution of grp-1, grp-2 and lin-5.
What are the official names of this protein?
Casein kinase I gamma, CKI-gamma.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cytoplasm. Note=Cortical localization during all cell cycle stages. In the cytoplasm, forms punctate structures around the asters during mitosis. Enriched in the anterior region of the 1 cell-stage embryo.
Protein: NU1C_GLOVI
Sequence: MEGIDLGNAFAQSLSGLGVPADVARALWLPLPMIVILLTVTVGVIAAVWGERKWSGMMQQRMGPTIIGLGGSIQGAADGVKLLVKEDIIPVKADPWLFTLGPAIVIIPVFFSYLVIPFGQGLVLSDITIGIFFIIAVASISPIGALMAGYASNNKYALLGGLRAAAQSISYEIPLALSVLAIVMMSSSLSTVDIVEQQETLGLFSFFSWNIWRQPIGFVIFLISALAETERAPFDLPEAESELVAGHHTEYTGMKFALFYLSEYANLILASLIASVLFLGGWSFIVPLEPLAALFGIEASNPIFQVVNALVGISVTILKATFFVFLAILARWTLPRVRIDQLLDLGWKFLLPVSLFNLLLTAALVLLSNTLKTTLPLYLPLIIFVGLVFVAMSLQKRPAAKPTAARA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, NAD(P)H dehydrogenase I subunit 1, NDH-1 subunit 1, NDH-A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMG_PECAS
Sequence: MSQLELETCNLTLVRYPQVAENSALQAWDAADEYLLRELSTMEIAPGPRLIFNDTFGALACGLQAQSPVSISDSYLSQLATRHNLELNGYDADAVTLLDSMADLPDAPALVVMRIPKTIALLEHQLRMLRKVVTPQTRIIAGAKARDIHTSTLQLFERVMGPTKTSLAWKKARLVHCEWAELKVSEQSLTTEWELDGYGYRIQNHANVYSRNGLDIGARFFMQHLPEQIDGKIIDLGCGNGVIGLAALEANPDATVGFFDESYMAVASSQMNVEVNRPQDVERCSFVVNNGLSRVRRDTLQAVLCNPPFHQLQAVTDEIAWQMFMDARRCLQVGGELRIVGNRHLDYFHKLKRLFGNCETIASNTKFAVLRAVKTNSSR
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_JANSC
Sequence: MSAQELRDKTPDQLRDELTALKKEAFNLRFQQATGQIENTARMRQVRRDAARVKTILNEKAAAAANAEA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ILVC_KOCRD
Sequence: MAKIYYNDDADLSIIQNRSVAIIGYGSQGHAHALNLRDSGVDVRIGLNEGSKSRAKAEAEGLQVMSIAEAAKEADVIMILTPDQVQAQVYEESIKDNLEEGDAIFFAHGFNIRFGYIEAPQGVDVAMVAPKGPGHTVRREFEAGRGVPDLVAVEVDASGNALQLALSYAKGIGGTRAGVIETTFTEETESDLFGEQAVLCGGMSHLVQYGFEVLTEAGYQPEIAYFEVLHELKLIVDLMVEGGIAKQRWSISDTAEYGDYVSGPRVIDPSVKERMQDVLKDIQEGVFADRFMKDQASGAKEFKELRAKEEKHPIETTGRKLRSLFAWEQTDADYTEGTAAR
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ATPA2_GLUOX
Sequence: MPDTDQAASWLASARSSLTDISVGPRTDRTGRVEDIGDGIALISGLPDAKLDELLSFGNGRYGFVHGLEEDSIGCILLNNEGTIEAGDAVQGTSGVVSVPVGPGLLGRVVDPLGRPLDGKGPVEAETWFPVERPAPAIIDRELVTEPVQTGTLAIDTLFPIGRGQRELIVGDRATGKTTIAVDAILAQKSNDMICVYVAIGQKTSSVQRVIETIRTRGNPDRCIIVVARPAEAPGLCWIAPFAAMSMAEYFRDRGQHALLVIDDLSKHAATHREVSLLTGRPPGREAYPGDIFYVHARLLERAAKLSAAKGGGSLTALPVAETEAGNLSAYIPTNLISITDGQIVLNRTLFDQGQKPAVDVGVSVSRVGGAAQSPILRSSVGTLRLDYAQFIELEAFTRFGGLPDTHVRQQLARGACIRATLRQGPHAPLDLLQEVALVTASQNGLLDGVTAKNIRTIQSGLGDYLRSNASEISTAIESGGVLSAEQKERFVACLRQYVEPRASAAS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIC1_DANRE
Sequence: MYFLSGWPRRLLCPLRSDERPFRIEPSAQRFYLAVLSETQISIWFSRPSVLIVSYIESGKAAAQFGFYQQVEWKPDDSMIAVAAANGYVLLFDIIGGLDDKYLYEPVYPKGSARVKVTPGYKEEQCAPALTLEMKKPVDLEAPISCLQSLAEDLLVATADGFLHMLHWDSVSNGRRAVNLCTIPFSLDLQSSRGGPCLDLDGVYIRDLEYCATLDGFAVVFDDGRIGFITPTANRLATDQLQGVWAADVTDGTCVAVNNKYRLMAFGCTSGSVLVYMIDSSTGCMQLSHKLELTPKHYPDIWNKTGPVKMIRWSPDCSVAMVTWECGGLSLWSVFGAHLICTLGEDFAYRSDGTKKDPLKISSMSWGVEGYHLWVIRSSDSTVTEEKQEKLQQNTILQFQFIKSSNQEQVLLQGEDRLYVTCGDPTQTQTPGQCRSSSTAPLSQGLSTLLGHKHWQVVQIHSTYLETNWPIRVRNAHDRRRVTLIMLMLTDHYAVCEQNMTVTGGLAWWNDFVVVACYNFIDRQEELRLYVRSANLDNAFASITKLHADTLLLNVFRNMVILFRADCSICLYSIERRHDGPSPSASVELLQEVSMSRYIPHPGLVVSVTLTSVRTESGITLKAPQQACSAESILLNLAGQLIMLQRDRSGPQVREKDAPANHSKLLPFCPPVVLAQCVESVWTSSRSNRKKRHLMEALWLSCGEAGMKVWLPLFPRDHRKPHSFLSRRIMLPFHINIYPLTVLFEDALILGASNETVLFDGLSSSAEPLEALFPYCTVERTSQIYLHHILRQLLVRNLGEQALMLAQSCASLPYFPHVLELMVHVVLEEEATSREPIPDPLLPTVAKFVTEFPLFLQTIVHCARKTEYALWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQGKWDLCRHMIRFLKAIGSGESETPPTTPTTQEQSPSSGFEFFRNRSISLSQSADSIAAGKFNLQKTMSMPTGPSSKSDSAENLYIDVMLWRHARRLLEQVRLRDLGCFSAQLGFELIGWLCRERTRVARVDDFVTALKCLHKDFLWPFPVIPACTISSPLKNGRCRPVLSSRLLKSQSADSLLNSEMDTTPPQVSTANHRWLDGLGAVSKELDSASSHGGPQTQEAFLSPLISKGEQVSDIYLYFHPSIHPIHLSIHPSIVLFIHSSFYPSIHPSFHPSIHPSIVLSIHPSIHRSIYLSIHPSIHPSIHPSIVLFIHPSIVPSIHPSIHPSIHPLFYLSIHPSIHPSIHRSIHPSIHRSIYPSIHRSIHPSIHRSIYPFIHPSIVLSIHPSIHC
What is the function of this protein?
The RIC1-RGP1 complex acts as a guanine nucleotide exchange factor (GEF), which activates RAB6A by exchanging bound GDP for free GTP, and may be thereby required for efficient fusion of endosome-derived vesicles with the Golgi compartment.  The RIC1-RGP1 complex participates in the recycling of mannose-6-phosphate receptors (By similarity).  It is a regulator of procollagen transport and secretion, and is required for correct cartilage morphogenesis and development of the craniofacial skeleton (PubMed:31932796).
What are the official names of this protein?
Guanine nucleotide exchange factor subunit RIC1, Protein RIC1 homolog, RAB6A-GEF complex partner 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane.
Protein: KTHY_LACLA
Sequence: MNGILISLEGPDGAGKTTVLKEILPEIQKMKREIVPTREPGGVRVAEEIRQIILDPKNTDIDSKTELMLFAAARRLHMQEKMLPALQAGKVVIVDRFIDSSVAYQGYGRDLGVEVVDWLNYFATDGLKPDLTLYFDVDTDVALERIMKNRADEVNRLDLERAEMHRKVREGYLEIVVKEPERFVKIDASQPLEKVVADTLSVLKKRFVSEF
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.