PharMolix/UniProtQA huggingface dataset:
Protein: PGLR6_ARATH
Sequence: MVYNTSCLILPLALIILDFTLISSLAHPIPSTLNVLSYGAKPDGSKDSTKAFLAAWDVACASANPTTIIVPKGRFLVGNLVFHGNECKQAPISIRIAGSIVAPEDFRIIASSKHWIWFEDVTDVSIYGGILDAQGTSLWKCKNNGGHNCPTGAKSLVFSGSNNIKISGLTSINSQKFHIVIDNSNNVNIDGVKVSADENSPNTDGIHVESSHSVHITNSRIGTGDDCISIGPGSTNVFIQTIRCGPGHGISIGSLGRAEEEQGVDNVTVSNVDFMGTNNGVRIKTWGKDSNSFARNIVFQHINMKMVKNPIIIDQHYCLHKPCPKQESGVKVSNVRYEDIHGTSNTEVAVLLDCSKEKPCTGIVMDDVNLVSVHRPAQASCDNANGSANDVVPFTPCLKREIIIT
What are the official names of this protein?
Probable polygalacturonase At2g43860, PG, Pectinase At2g43860.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: BIOB_SHIFL
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFEPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLGQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: LPXA_BART1
Sequence: MSGTKIHPTALVEKGAQLGENVRVGPFCHISSEAVIGDECSLTSHVVIMGKTMLGAKSKVFSHAVLGADPQNNKHKGGATILSIGKNCMIREGVTMHRGSDSSTGMTVVGDNCQFFCYAHIAHDCHVGNHVTFANNAMIAGHVTVGDYVIIGGGAAVHQFVRVGHHAFIGGVSALVGDLIPYGTAVGVQAKLAGLNIIGMKRAGLERQDIHALRHAVAMLFDHSKPFKERVNDVASCYSSSRSVADVVRFIKEEGKRFYCTPKFGGDRIK
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX53_BUCAI
Sequence: MNHIKNNPVIIIDGSLYLYASYYAFCNLENTSGKPCGAIYGMLKIIDNIFKKYKNLKKIIIIFDSSRKTFRNKLFKEYKKNRSSMPDLLVMQIQPLFEILKKIGIKTLTIPGIEADDVIGSLSYQLEKQGEKILILSHDKDMLQLVTENINIFHKKNNCIITSEIIQEKYGIKPKEFIDFLALMGDATDNIPGVPKIGIKTALFLINKFSNIENIYNNIEKIKSLPLRNAKNISIQLKNNKERALLSYKLARIKLDIPIDIKLKDIILKKYCSKNTFQIFKNYFSS
What is the function of this protein?
5'-3' exonuclease acting preferentially on double-stranded DNA.
What are the official names of this protein?
5'-3' exonuclease.
Protein: Y2140_MYCTO
Sequence: MTTSPDPYAALPKLPSFSLTSTSITDGQPLATPQVSGIMGAGGADASPQLRWSGFPSETRSFAVTVYDPDAPTLSGFWHWAVANLPANVTELPEGVGDGRELPGGALTLVNDAGMRRYVGAAPPPGHGVHRYYVAVHAVKVEKLDLPEDASPAYLGFNLFQHAIARAVIFGTYEQR
What are the official names of this protein?
UPF0098 protein MT2198.
What is the protein family that this protein belongs to?
Belongs to the UPF0098 family.
Protein: DAPH_STAAB
Sequence: MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFGSEQSKVIFCEADDWKPFYETYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIREQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGTVVAGTPAKVIKQASEVQDTKKEIVAALRKLND
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: THIM_NATTJ
Sequence: MSTFNSNFKLGTYLTQVRQENPLVHAITNYVTMNDCANITLAAGASPAMCESRDEVSDFVPLAKALYINIGTINQEHKDSIYLAAEKASELEIPIVLDPVGAVAIKSRLDLVKDLLTNYNVSCIKGNNAEIKCLAGRKGHGKGMDSLDLGEDIQMVNSELSEKYNTMVLATGKTDLITKGNITVKVSNGTPLLGRITGSGCMLGILISAFIGASDNDWEAGIAATVSMGVVGEMAEESISSSTDLGSFRVKIFDHMAALTSKELQERGNVSEL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: LIGB_PSEFS
Sequence: MMHLLFALLLSALPCWVWAQACSDEARAHVSTLAEQIRQWDDSYHRLGQSPVSDELYDQARQRLAQWHQCFPAPTATPNTPLASSRGAQPHPVAHTGLEKLLDEHAVDAWLGTRKDVWIQPKVDGVAVTLVYQQGRLRQVISRGDGVMGHDWSASARKIPGIVQQLPDPIDLVLQGELYWRLDDHVQSASGGLNARSKVAGLMNRKHLGDTDAAGIGLFVWAWPQGPAAFTERLSTLKRWGFTDTQRFSQPIRNISEAAHWRAYWYGHPLPFASDGVVLHQAQHAPAERWQVSTPYWAAAWKYPTTKALALVRDVQFKIGRTGRITPMLELEPVRLDDRQISRVSAGSLKRWQSLDIRPGDHVSISLAGQVIPRLDEVILRSSTRADLPVPNPGKFHALSCWQLDPGCEEQLLARLSWLSGNQGLALPHIGRETWSVLIQAGLIAGFLDWLTLDTAELANIDGFGDRTRARVVDSFHSARQRPFAQWLKALGVPPAARNNLEGDWQTLVARDTQAWLAIDGIGPGRAAQLSAFFRDPHVQALAETLRVAGIDGF
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: ECH19_MYCTU
Sequence: MATVESGPDALVERRGHTLIVTMNRPAARNALSTEMMRIMVQAWDRVDNDPDIRCCILTGAGGYFCAGMDLKAATQKPPGDSFKDGSYGPSRIDALLKGRRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLYPMGGSAVRLVRQIPYTLACDLLLTGRHITAAEAKEMGLIGHVVPDGQALTKALELADAISANGPLAVQAILRSIRETECMPENEAFKIDTQIGIKVFLSDDAKEGPRAFAEKRAPNFQNR
What is the function of this protein?
Degradation of the cholesterol side chain involves 3 multistep beta-oxidation cycles, this may be involved in the second cycle (Probable).  Hydrates 3-OCDO-CoA ((22E)-3-oxo-chol-4,22-dien-24-oyl-CoA) to make (22R)-HOCO-CoA (3-oxo-chol-4-ene-(22R)-hydroxy-24-oyl-CoA).  Also acts on octenoyl-CoA.  Not active on (E)-3-OCDS-CoA ((E)-3-oxocholest-4,24-dien-26-oyl-CoA) or 3-OPDC-CoA (3-oxo-4,17-pregnadiene-20-carboxyl-CoA).  Hydrates the same substrate as ChsH3, but the 2 enzymes make different stereoisomers of the product (PubMed:32649175, PubMed:33826843).
What are the official names of this protein?
Enoyl-CoA hydratase EchA19.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: CORE5_ADE12
Sequence: MPSMTKRKFKEELLQALAPEIYGPSDNLTKRDIKHVKKREKKEEEVAAASADGVEFVRSFAPRRRVQWKGRQVKRILRPGTTVVFSPGERTIMRPLKREYDEVYADDDILEQAAQQTGEFAYGKKGRYGDKIAIPLDEGNPTPSLKAVTLQQVLPVLGPSEEKRGIKREAMDELQPTMQLMVPKRQKLEDVLEHMKVDPSVQPDVKVRPIKKVAPGLGVQTVDIQIPVQTALGETMEIQTSPIKTTVNASVQTDPWYPPVLSTKKKRHYRQTSSLLPDYVLHPSIVPTPGYRGTTFQRRATAPSRRRGPSRRRRRRKATLAPAAVRRVVQRGRTLILPSVRYHPSIL
What is the function of this protein?
Associates loosely with the viral DNA to form an outer shell around the nucleoprotein-DNA complex and links it with the capsid by binding the endosome lysis protein.  Dissociates from the viral genome during entry.  Might be involved in nuclear capsid assembly of the viral particles through its association with NPM1/nucleophosmin.
What are the official names of this protein?
Core-capsid bridging protein, Core protein V.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae core-capsid bridging protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus, host nucleolus. Note=Located inside the capsid (core). Present in 157 copies per virion. Localizes in the nucleoli during infection, then translocates from the nucleoli to the nucleoplasm as the infection progresses and is finally incorporated into the viral particles.
Protein: FLGI_BRASB
Sequence: MRRVRTTRLFQVACAAIVALASSAMSAHATSRIKDLANIEGVRQNQLIGYGLVVGLNGTGDTLNNIPFTKQSLQAMLERMGVNIRGATIRTGNVAAVMVTGNLPPFATQGTRMDVTVSALGDAKNLQGGTLLVTPLLGADGNVYAVAQGSLAISGFQAEGEAAKIVRGVPTVGRIANGAIIEREIEFALNRLPNVRLALRNADFTTAKRIAAAINDFLGVKTAEPIDPSTVQLSIPPEFKGNVVAFLTEIEQLQVDPDLAAKIVIDERSGIIVMGRDVRVATVAVAQGNLTVTISESPQVSQPNPLSQGRTVVTPRTSVGVTEDGKKFAVVKDGVSLQQLVDGLNGLGIGPRDLISILQAIKAAGAIEADIEVM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar P-ring protein, Basal body P-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgI family.
What are the subcellular locations of this protein?
Periplasm. Bacterial flagellum basal body.
Protein: SPAN2_BPP21
Sequence: MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPRLPPAWIMQPPPDFTWQTPLNGIISPSERG
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit (Probable).  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans (By similarity).  Host outer membrane disruption is due to local fusion between the inner and outer membrane performed by the spanin complex (By similarity).
What are the official names of this protein?
Spanin, outer lipoprotein subunit, o-spanin, Lysis protein Rz1, Outer membrane lipoprotein Rz1.
What is the protein family that this protein belongs to?
Belongs to the Lambdavirus o-spanin family.
What are the subcellular locations of this protein?
Host cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: GATA_LEVBA
Sequence: MDYFKTDLASLHADLVAKKISARELTQATFDNIKTTDAQVDAFLTLNEDAALKQATKIDEQGVATDQPLAGIPVALKDNIVTKGLKTTAASKMLANFNPVYDATVTEKLAQAQMITVGKTNLDEFAMGGSTENSAFKTTKNAWDYTKVPGGSSGGSAAAVASGQVLAALGSDTGGSIRQPAAFNGIVGLKPTYGRVSRWGLIAFGSSLDQIGPMTRSVKDNATMLSAIAGHDEHDLTSSTQPVPDFAADLTDATSVKGMRIGLPKEFLADGVADDVKQAILAAADTYRQLGATVDEVSLPHNKYGVAAYYIIGSSEASSNLQRFDGIRYGHRADDVKNLEDVYVKSRSEGFGDEVKRRIMLGTFSLSAGFYDAYFLKAAKVRTVIMNDFKAVLKDHDFIMGPVAPTPAFGIGDEIKDPITMYMNDVLTIPVNLAGLPGLSLPAGFSQGLPVGMQLIGRPFDESTLYKAGYAFEQNTDFHLQVPTLGGQH
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ALF_MAIZE
Sequence: MSAYCGKYKDELIKNAAYIGTPGKGILAADESTGTIGKRLSSINVENVEENRRALRELLFCCPGALQYISGVILFEETLYQKTKDGKPFVDVLKEGGVLPGIKVDKGTIEVVGTDKETTTQGHDDLGKRCAKYYEAGARFAKWRAVLKIGPNEPSQLAIDLNAQGLARYAIICQENGLVPIVEPEILVDGPHDIDRCAYVTETVLAACYKALNEHHVLLEGTLLKPNMVTPGSDSKKVTPEVIAEYTVRTLQRTVPAAVPAVLFLSGGQSEEEATRNLNAMNKLSTKKPWSLSFSFGRALQASTLKAWAGKVENLEKARAAFLARCKANSEATLGTYKGDAAADTESLHVKDYKY
What are the official names of this protein?
Fructose-bisphosphate aldolase, cytoplasmic isozyme.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALBA1_SACS2
Sequence: MSSGTPTPSNVVLIGKKPVMNYVLAALTLLNQGVSEIVIKARGRAISKAVDTVEIVRNRFLPDKIEIKEIRVGSQVVTSQDGRQSRVSTIEIAIRKK
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  May be involved in DNA compaction.  May bind rRNA and mRNA, playing a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.
What are the official names of this protein?
DNA/RNA-binding protein Alba 1, Sso10b.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: SPX2_ORYSJ
Sequence: MKFGKSLSSQIVEMQPEWRDNFLSYKDLKKRLNLISGGAAGERASKRRRVGGATAVTVTAAAAGGMTLEQAGFVGLLDAELDKFNFFFLEKEEEYVIKQKELRERKMASAEEVMRVRKEIVDLHGEMVLLENYSALNYTGLVKILKKYDKRTGSMIRLPFVQKVLQQPFFTTDLLYKLVKECEEMLDQLMPTNEHSVASEDGKDDSEGEEKGSKPSSSSSANGGAVPGEAEAEDERSTDMKSTVTAALRALREIRSGSSTVSVFSLPPLHGSNGQDEPGR
What is the function of this protein?
Inhibits PHR2 DNA-binding activity via a phosphate (Pi)-dependent protein interaction (PubMed:25271318).  Together with SPX1, plays a negative role in the regulation of leaf inclination by preventing RLI1 transcription factor activity in Pi depleted conditions (PubMed:29610209).
What are the official names of this protein?
SPX domain-containing protein 2, Protein SPX DOMAIN GENE 2, OsSPX2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DXS_CHRSD
Sequence: MKLFDEIPAERPATPLLDTCEHPAALHDFNATQLRQLADELRAYLLYSVGCTGGHFGAGLGVVELTVALHHILDTPYDRLVWDVGHQAYPHKILTGRREQMSTIRQFGGLAAFPKRDESPYDTFGVGHSSTSISAALGMALAARTKGERRRVCAVIGDGALSAGMAFEALAHAGHVDANMLVILNDNEMSISENVGGMASYLARILVSKPYTVMRENSKRVLSHLPGALELARRTEEHVKGMVSPATLFEEMGFNYIGPIDGHDLPTLVQTLGNMANLEGPQFLHIKTCKGRGFRPAEADPIGYHAITKLEKTTSEPPPKKEPRSPNAATAEPEAQPKPQPKPRKYCNVFGEWICDMAAVDARLIGITPAMREGSDLIRFSREYPERYYDVAIAEQHAVTLAAGMACEAMKPVVAIYSTFLQRGYDQLIHDVAVQALDVTFAIDRAGVVGEDGPTHHGALDLSFLRCIPGMIVLAPADEAECRAMLSAAYHHPGPAAVRYPRGTGPGTQVASNLEALPIGEAETRRSGREGGVALLAFGSMNGPAGEVAERLDATHLNMRSVKPLDREAILAAARDHRLLVTLEESVVAGGAGSGVNELLAAEGVQVEVLNLGLPDDFVEHGKPAELLAACGLDAEGIETAVRRRLETSRADD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: INP4B_MOUSE
Sequence: MEIKEEGTSEEGQHFLPAAQANDPEDIQFTSIQKIPNEPQLEFILACRDLVAPVSDRKLNTVVQISVIHPVEQTLTRYSSTEIVEGTKDPLFLTGVTFPPDYPIYEETRIKLTVYDVKDKSHDTRSFLGCASFKVGELLKSKEQLLSLSLRTSDGGKVVGTIEVSLVKMGEIEDGDTDHITTDVQGQKCALMYESTAPESLSGKENLPFMNAVLRNPVCKLYRFPTSDNKWMRIREQMSESILSFHIPKELISLHIKEDLCRNQELKELGDLSPHWDNLRKNVLSHCDQMVTMYQDILTELSKETGSSFKSSSSKGEKTLEFVPVNLHLQRMQVHSPHLKDALYDVITVGAPAAHFQGFKNGGLRKLLHRFETERRNTGYQFIYYSPENTAKAKEVLSSINQLQPLIATHADLLLTSASQRSPDSLKSSLKLLSEKTELFVHAFKDQLVRSALLALYTARPGGILKKPPSPNVSTEEKSTQHDTPQLRRQDSIPHHSDYDEEEWDRVWANVGKSLNCIIAKVDKLIERDSHNEEGAGGSSSKDGEADHTLEDSITSHPREDWYEQLHPLILTLKECMGEVVNRAKQSLTFVLLQELAYSLPQCLMLTLRRDIVFSQALAGLVCGFIIKLHTSLHDPGFLQQLHTVGLIVQYEGLLSTYSDEIGMLEDMAVGISDLRKVAFKITEATSNDVLPVLTGRREHYVVEVKLPATVFESLPLQIKEGQLLHVYPVLFNVGINEQQTLAERFGDVSLQESINQENFELVQEYYSIFMEKMPPDYISHFQEQTDLKGLLDNLHQNIQAKKRKNVEIMWLAATICRKLNGIRFTCCKSAKDRTSMSVTLEQCSILRDEHQLHKDFFIRALDCMRSRQTQGALNESDDPETGCLTDNKPTSRHFYPVALLLVSSHLLVVWLILSLALLLAKYQ
What is the function of this protein?
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate and inositol 3,4-bisphosphate (By similarity).  Plays a role in the late stages of macropinocytosis by dephosphorylating phosphatidylinositol 3,4-bisphosphate in membrane ruffles (By similarity).  Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (By similarity).
What are the official names of this protein?
Type II inositol 3,4-bisphosphate 4-phosphatase, Inositol polyphosphate 4-phosphatase type II.
What is the protein family that this protein belongs to?
Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.
Protein: NAPA_PASMU
Sequence: MNLSRRDFMKTNAAVAAAAVAGLAIPVKNVEASPDKIIKWDKAPCRFCGTGCSVLVGTQNGRVVASQGDPDADVNRGLNCIKGYFLPKIMYGKDRLTSPMLRMTNGKFDKHGEFTPVSWDQAFTIMAEKFKKALKEKGPNGAGMFTSGQSTIFEGIAKSKLFKAGLRSNNIDPNARHCMASAAVAFMRTFGMDEPMGCYDDIEKADAFVLWGSNMAEMHPILWSRISDRRLSHPDVKVAVLSTFEHRSFELADLGVIFTPQSDLAIMNYIANYLIQHDAIDHDFIQKHTKFKRGETDIGYGLRETHELEKAAKNVKTAGKMHDSDFEEYKKLVAPYTLEKAHEISGVPKEQLEALAKMYADPKLNIVSFWTMGFNQHTRGVWANHLIYNIHLLTGKISKPGCGPFSLTGQPSACGTAREVGTFAHRLPADLVVTNPKHVEKAEKLWKLPKGVIQTQVGYHAVAQDRALKDKKMNVLWQMCTNNMQGGPNINQERFPGWRDEENFVIVSDPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWYQQVKAPGESKSDVWQLVEFSKYFTTDEMWPAEVLAANPEYKGKTLYEVLFRNGQVDKFQVPTDKPGYMNDEAEHFGFYLQKGLFEEYAVFGRGHGHDLADFETYHKARGLRWPVVDGKETLWRYREGYDPYVKEGEGVAFYGYPDKKAIILAVPYEPPAEAPNAEYDLWLTTGRVLEHWHTGTMTRRVPELHRSFPNNLVWMHPLDAKKRGLRHGDKVKISSRRGEMISHLDTRGRNKVPQGLVYTTFFDAGQLANYLTLDATDPISKETDFKKCAVKVEKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: GUB_ACET2
Sequence: MKNRVISLLMASLLLVLSVIVAPFYKAEAATVVNTPFVAVFSNFDSSQWEKADWANGSVFNCVWKPSQVTFSNGKMILTLDREYGGSYPYKSGEYRTKSFFGYGYYEVRMKAAKNVGIVSSFFTYTGPSDNNPWDEIDIEFLGKDTTKVQFNWYKNGVGGNEYLHNLGFDASQDFHTYGFEWRPDYIDFYVDGKKVYRGTRNIPVTPGKIMMNLWPGIGVDEWLGRYDGRTPLQAEYEYVKYYPNGVPQDNPTPTPTIAPSTPTNPNLPLKGDVNGDGHVNSSDYSLFKRYLLRVIDRFPVGDQSVADVNRDGRIDSTDLTMLKRYLIRAIPSL
What are the official names of this protein?
Beta-glucanase, 1,3-1,4-beta-D-glucan 4-glucanohydrolase, Endo-beta-1,3-1,4 glucanase, Laminarinase, Lichenase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
Protein: RS13_MARSD
Sequence: MARIAGVDLPKNKRLDIALTYIYGVGRTTALKILDTVGIDWTLKTDDLSGEQVNTIRKELEDNYKVEGDLRRDQIADIKRLMDIGCYRGLRHRRGLPVRGQSSKTNARTRKGPRRSVMSRKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MFNB_METM6
Sequence: MILLVSPKDVAEAYEAIEGGADIIDVKNPPEGSLGANFPWVIKETREATPEGMLVSAAIGDVPYKPGTVTLAALGATVSGADYIKVGLYGTRSYQEALDVMKNVTKAVKAVGENKIVVAAGYADAYRVGGVDPLVIPRVARDAGCDVAMLDTAVKDGKTLFDHMSIELLKEFVEETHKYGMKCALAGSIKIEEIPMLKEINCDIVGVRGAACTKGDRNEGRIQKDLVKEIVKVCKE
What is the function of this protein?
Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
What are the official names of this protein?
(5-formylfuran-3-yl)methyl phosphate synthase, 4-(hydroxymethyl)-2-furancarboxaldehyde-phosphate synthase, 4-HFC-P synthase.
What is the protein family that this protein belongs to?
Belongs to the MfnB family.
Protein: CH10_STRAG
Sequence: MLKPLGDRVIISFVETEEKSVGGFVLAGASHDATKTAKVLAVGDGIRTLTGELVAPSVAEGDTVLVENDAGLEVKDGNEKVTVVRESDIVAVVK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_LEPIC
Sequence: MSLKSLLKGFKRPKKIEFNTEANTPNYGKFVAEPFERGFATTIGNSLRRTLMSSIEGAAISAIRIEGVNHEFSFIEGVAEDVTRIILNLKQVRIKYEPEEKDQSKIIHLELKGAGYFRAGDLAVDSSIEIMNPDLHIATLNEDANLVMDLEIQRGRGYVPAEEKKKDIEVLGTIPVDSIFSPVQKVVFEVSETRVAQRSDYEKLTLEVWTDGSVSPDDAVAQAAKILKEHLTVFINFEEELEEEDDELDEADEKLKASLSKHVEELELSVRSLNVLRSLEIDFIGDLVKRSEEEMSKSKHYSDQCLQELKVKLSTLGLSFGMRDF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RLMH_LEPCP
Sequence: MKLLLIAVGQRLPAWADTAYEDYAKRFPPDLRLELKAVKTEARTTGKPVEALMAAEKTRIEAALPRGCRRVVLDEHGQRVTTAQLAERLAVWQRDGRDVALLVGGPDGLDQTLRDGADEKLRLSDLTLPHAFVRVMLAEALYRAWTLSIGHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_ALLVP
Sequence: MSSENVPSFRWTQSLRRGLSNWTHAVKGDVLADARAIVSALDFHQVAQVQRMMRKDKRSEADLTRLRDMNKEVDALMMMRSAQKDNILKVGGLSKDELMELASDLDKLRKKVQRTEGGGQPGVYAGNLTSSQLNQRSEILKMMGMGTGPRGPVGGVVKVWDIKDSSLLVNQFGSMPALTIACMTQQGGEQMNDVVQALTSLGLVYTVKYPNLSDLEKLTEKHPCLKLITQEPAQINISGYNLSLSAAVKADACMIDGGNMLETLQVKPSMFSTLIKTILEVKNREGMFVSPSPGQRNPYENILYKVCLSGDGWPYIGSRSQIKGRAWENTTVDLEGKPSVNHPPVRNGGSPDLKQIPKTKEDEVIRAIEQLDPRGTTWVDIEGPPGDPVELALFQPETGNYLHCYRRPHNENAFKDQSKFSHGLLLKDLADTQPGLISCIIRHLPNNMVLTAQGNDDIIKLLEMHGRRDIKVLDVKLSSDQARLMEDVVWERYNMLCVKHTGLVIKKKKKGAAPGSANPHCALLDCIMFDATVTGYLRDQKPKRLLPLDTLYRDNANLINL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: ECFA1_STRPC
Sequence: MSAIIELKKVTFNYHKDQEKPTLDGVSFHVKQGEWLSIIGHNGSGKSTTIRLIDGLLEPESGSIIVDGDLLTITNVWEIRHKIGMVFQNPDNQFVGATVEDDVAFGLENKGIAHEDIKERVNHALELVGMQNFKEKEPARLSGGQKQRVAIAGAVAMKPKIIILDEATSMLDPKGRLELIKTIKNIRDDYQLTVISITHDLDEVALSDRVLVMKDGQVESTSTPEQLFARGDELLQLGLDIPFTTSVVQMLQEEGYPVDYGYLTEKELENQLCQLISKM
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.