PharMolix/UniProtQA huggingface dataset:
Protein: C719A_SINHE
Sequence: MEMEMSVLAMSSTLILALAMALIFLFKAKSSSAIKWPPGPKTLPIIGNLHQLGGDELHIVLAKLARVHGAIMTIWMAKKPVIVVSDVNSVWEVLVSKSSDYAARDAAEISKIVSASSHSINTSDSGPYWQTLRRGLTHGPLGPLNISAQIPIQQRDMQRVIREMQQDAAANGGIIKPLDHLKRSSTRLVSRLIFGDTFDNDPYNDSMHEVVQDLNRFGGIALLEQAFSFAKHLPSYKRGVKEFHIHKRKIDDLVRPVVASANPPSNSYLGFLQSQNYSEEIIIACIFELYLLAMDSSASTATWALAFMIRDQQVQEKLYQDIKRVIGDGVDLVKAEDLSKMHYLQAVVKETMRMKPIAPLAIPHKTAIDTTVMGTKVPKGTCVMVNLYALHHDESVWAKPYTFMPERFLQGEDGKSVTEQAFLPFGAGMRICGGMEVGKLQFSLALANLVNAFKWTSAAEGKLPDMSDELQFITVMKTPLEARIIPRNP
What is the function of this protein?
Cytochrome P450 involved in the biosynthesis of etoposide, a chemotherapeutic compound of the topoisomerase inhibitor family (PubMed:23161544, PubMed:26359402).  Catalyzes the conversion of matairesinol to pluviatolide (PubMed:23161544, PubMed:26359402).
What are the official names of this protein?
Pluviatolide synthase, Cytochrome P450 family 719 subfamily A polypeptide 23.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THIE_LEVBA
Sequence: MSVTFEPGLLRAYFVAGSQDVPGQDLRDVLAKMLAAGITAFQFRDKATSTLTPEQRLALGRDLRAQCRVANVPFIVDDDVELALALDADGIHVGQSDQRVQQVIQAVAGRNIFVGLSCSTMAEVTAANAIAGIDYIGSGPIFPTISKADADPVVGTAGLQKLVAQSRVPVVAIGGVTVDSLPAIAETGAAGVAVITLLTHSHDVDADTAAMRQAFSK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: RL18_RICCN
Sequence: MRSAKLKFEKRRSRIRHKISKTSNRVRLSIFKSGRHIYAQIIDDSKSITIAAASTLDEKIKKLKKSHCNIENAIKVGEEIAKKADSAGIKDVVFDRGGYKYHGVVKALADAAREKIKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: AATP9_ARATH
Sequence: MAMMGQLWTNTGSALATLMFVYTIFKQFFPLFGPQLEPFLYRLFGRFYPYIQITFHEYSGEHFKRSEAYLGIQSYLSKDSSARAKKLKANTTKGSKSIVLSMDDKEEITDDFEGIRVWWQSKKEGATRQSFSFYPEANEKRYYMLRFHRRDREVIIERYLEHVMREGKTIEQKNRERKLYSNTPGQSHGNNSKWSHVTFEHPATFDTLAMEENKKEEIKSDLIKFSKSKDYYKKIGKAWKRGYLLFGPPGTGKSTMIAAMANFLEYDVYDLELTTVKDNTHLRRLLIETSAKSIIVIEDIDCSLNLTGQRKKKEEEEEDGDDKNTIEKKMMMKNEGENKESKVTLSGLLNFIDGLWSACGGERIIVFTTNFVDKLDPALIRKGRMDKHIEMSYCCFEAFKVLAKNYLDVEESEMFEEIKRLLEVEEIKMTPADVGENLLPKSEKEGGETCLKRLIEALKEEKEEAKKKVEEEEEEKQRKKEKVKEIEAEKEKKKKIEEEN
What are the official names of this protein?
AAA-ATPase At3g28580.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ZN460_HUMAN
Sequence: MAAAWMAPAQESVTFEDVAVTFTQEEWGQLDVTQRALYVEVMLETCGLLVALGDSTKPETVEPIPSHLALPEEVSLQEQLAQGVPRYSYLGQAMDQDGPSEMQEYFLRPGTDPQSEKLHGKMSLEHEGLATADGICSMMIQNQVSPEDALYGFDSYGPVTDSLIHEGENSYKFEEMFNENCFLVQHEQILPRVKPYDCPECGKAFGKSKHLLQHHIIHTGEKPYKCLECGKDFNRRSHLTRHQRTHNGDKPFVCSECGRTFNRGSHLTRHQRVHSGEKPFVCNECGKAFTYRSNFVLHNKSHNEKKPFACSECGKGFYESTALIQHFIIHTGERPFKCLECGKAFNCRSHLKQHERIHTGEKPFVCSQCGKAFTHYSTYVLHERAHTGEKPFECKECGKAFSIRKDLIRHFNIHTGEKPYECLQCGKAFTRMSGLTRHQWIHTGEKPYVCIQCGKAFCRTTNLIRHFSIHTGEKPYECVECGKAFNRRSPLTRHQRIHTAEKSHEPIQSGNVSCESTDLIQHSIIHTESSPVSAVNMETPSIAAHSSSLDINGFIVEETLPL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 460, Zinc finger protein 272, Zinc finger protein HZF8.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS5_CARRP
Sequence: MEKKLIKIHRVTKVVKGGRIFSYTATSIVGNRKKNIGLGRGKSREVLESIKKSYLKAKKNILKLNFSKNIIPYFLFAKHCATKVFLYPANDIIGLIASKYVKQVLNIIGVFSVFSKIHGSTNAINVVICTIKALSLIKK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y1335_ARCFU
Sequence: MVSRTTTSIPINFRGVGVYKTFANKNLLYCNCNIVSMEKTDLLMMTFAIVNLADYMTTVKGIEMGFHELNEFVSSLNPASFLLLKIAIVATAFALLLYTRRLSFSLGRGIYIGLVAGLAISTAVLGICSVHNLLLLTGFPEVEFLVKVMTGVLALI
What are the official names of this protein?
Uncharacterized protein AF_1335.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HTPX_STRT2
Sequence: MLFDQIARNKRKTWLLLLVFFLLLGLVGYGVGNLWLGSGFGGLILALVIGFIYVVTMIFQSTNVVMAMNGAREVDEQTAPNLYHVVEDMAMVAQIPMPRVFIVDDPSMNAFATGSSPKNAAVAATTGLLAVMNREELEGVIGHEVSHIRNYDIRISTIAVALASAITMLAGMARNMMLWGGGRRRNDDDRDGSSGLEIVFLILSLIAIILAPLAATLVQLAISRQREFLADASSVELTRNPQGMINALLKLDNSAPMQHHVDDASAALFINDPKKESGLQKLFYTHPPISERVERLKQM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1426_METJA
Sequence: MRTILNKLNINGEIMLIKDIMKKPIVVYEDNDLIDVIRLFRKNKISGAPVLNKDGKLVGIISESDIVKTIVTHNEDLNLILPSPLDLIELPLKTALKIEEFMEDLKNALKTKVRDVMTRKVIVAKPDMTINDAAKLMVKNNIKRLPVVDDEGNLIGIVTRGDLIEALI
What are the official names of this protein?
Uncharacterized protein MJ1426.
Protein: MURC_SALPB
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLTSLGATIFFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYHGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQGMPDLHVTLNAPGRHNALNAAAAVAVATEEGIADDAILRALESFQGTGRRFDFLGEFPLEPVNGKAGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRYTRTRDLYDDFANVLTQVDALLMLDVYPAGEAPIPGADSRSLCRTIRNRGKIDPILVSDPAQVATMLAPVLTGNDLILVQGAGNVGKIARYLSEIKLKPQIQEEEQHG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_PARUW
Sequence: MLVLGIESTCDETACAIVRDGKDILSNIVASQIDLHKEYGGVVPELACRRHIDLIIPVIDQALNQAKLTLEQIDLIAVANGPGLIGALLIGLNTAKALALALRKPFIGINHVEAHLYAAIMSHPQDFQFPCLGVVLSGGHTALVLIKQIGQYELIGQTVDDAVGEAFDKVAKMLNLPYPGGPEIENLARHGRSVKFNFKAGQVKGRPLDFSFSGLKTAVLYAIKDPKALKEMVLLSSEMTQDIAASFQEAACSDIVKKSLLAAKQYGVNTLLFGGGVTNNCYLRKLFSVANSNLNYIWPSAGLSLDNAAMIAGLGYYRYQLQNKSDSMDLEPLTRTPLQSVKE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACNA_ECOLI
Sequence: MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKVLLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAAMREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFLKWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLRKHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSEDQVELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKAFAASNELEVNATHKDRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLLAKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNSGPLPDPIETAIKKSDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNINLASEPIGHDRKGDPVYLKDIWPSAQEIARAVEQVSTEMFRKEYAEVFEGTAEWKGINVTRSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGSIKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTRHLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESFERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADGSQEVVPCRCRIDTATELTYYQNDGILHYVIRNMLK
What is the function of this protein?
Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  The apo form of AcnA functions as a RNA-binding regulatory protein which plays a role as a maintenance or survival enzyme during nutritional or oxidative stress.  During oxidative stress inactive AcnA apo-enzyme without iron sulfur clusters binds the acnA mRNA 3' UTRs (untranslated regions), stabilizes acnA mRNA and increases AcnA synthesis, thus mediating a post-transcriptional positive autoregulatory switch.  AcnA also enhances the stability of the sodA transcript.
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, Iron-responsive protein-like, IRP-like, RNA-binding protein, Stationary phase enzyme.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: PUR5_BACLD
Sequence: MSESYKNAGVDIEAGYEAVKRMKKHVERTKRIGAMGGLGGFGGMFDLSELPYKQPVLISGTDGVGTKLKLAFAMDKHDTIGIDAVAMCVNDVLAQGAEPLFFLDYLAVGKADPVKIEEIVKGVAEGCVQSGSALVGGETAEMPGLYTEDEYDIAGFSVGAAEKDGIVTGENISEGHLLIGLSSSGLHSNGFSLVRKVLLEDAGLNLDETYAPFERPLGEELLEPTKIYVKPVLEAVKSGKIAGMAHVTGGGFIENLPRMMPDGLGVEIDIGSWPVPPIFPFIQEKGGLKSEEMFNVFNMGIGFVLAVKEEDMTDVIQTLENNGEKAYLIGRVKAGSGVVFGGAGLS
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_RHOP2
Sequence: MRILCTNDDGIHAPGLKIVEDIARALSDDVWVVAPELDQSGVSHSLSLNDPLRLREVGPRHFAVRGTPTDCVIMGARHILADKAPDLVLSGVNRGRNVAEDVVYSGTIAGALEGTILGLPSFALSQEFTLETRNAPLWDTAKAHGPEILRKAIKAGVPKNTVININFPACAPDEVAGVQVTRQGKRNQGFLRVDERHDGRGNPYFWIGFERVAVVDMPAEGTDLAALAAKYISVTPLRLDRTDEAFSATLAKTLG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCPB_MYCPU
Sequence: MVQLELKKDQIMKNKIIEALMYFQGDQGLSPEQVKEVFDLEKDQEGKKLLNDFMEFYNAREGGTKVFVFGEIYKIATIEPLKDYVSKLVSIVRYQKLSKAAIEVAGIVAYKQPITKSMINEIRGVASDQVVNTLLVKNLIEEVGISPTPGKPVLYGITNKFYDYFKIKSLQELPNLSEFDFVQSIDEEQEEEQSYEGFNLFSSQREN
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: YP084_YEAST
Sequence: MSEKASEERPIRLAVLGGTSTGKTSLVSRLTVNIVHEVHYPTRNQTNWLFGFVPSSILARAILDEQAHERLCLRSPSSQTLEPIFPSPQVSKNVLLSPLVFQASTDNFQSVRLHNKSHSRRSLSLDKSDSPLYQTFSNDINSQSVPKIKADQLNVIEHFKLPLNYIPPTYAPIQIDIIDTPGFSPDNVVPFLEVSLFRNLGKSILHGLADEPRRPVSTTSLLVASGASELNGKVDGYILVYSAVPELNHIGGPPEYGDDVMNTDTENVSDGGFELLKVIRNCILDAWTEFRNYEKRWEEGKEDDIYSLVYSLRHLWSKNSKEKSAKIEQLRSYNTKLKSIELDPSSPDSPPPCIIVCSHVNHELASPMLIEMGRQLATKWKYGFVGIDSMDDLNVDVAVSLLIKEISEKMKLLVSNSNGSSSSGNSSSIYNSHLMNDKKKNNNAGLNKNMLKKIIK
What are the official names of this protein?
Uncharacterized protein YPR084W.
Protein: YVAP_BACSU
Sequence: MNQSEMCPRFEKAVDILSKRWVALIVFQLLNGSQRFSEIEAALPNLSGRVLSERLKELELEGVVKRDVIPETPVRIEYSLTDKGKALAPILGEISKWATEWIDPSFLD
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YvaP.
Protein: CDD_ECO8A
Sequence: MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDYLPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHSIDRVLLA
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: LMCD1_PIG
Sequence: MAKVAKDLNPGVQKMSLGQQQSARGVPCLRCKGTCSGFEPHSWRKICKSCKCSQEDHFLSSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAYYRRRQLMHQLPIYDQDPSRCRGLLESELKVMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETAAPTANGSLGDPSKEYVCELCKGVAPADSPVVYSDRAGYSKQWHPACFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFSEDYQRVEDLAWHRKHFVCEGCEQQLGGRAYIITKGQLLCPTCSKSKRT
What is the function of this protein?
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes.  Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters.  Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter.  Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway (By similarity).
What are the official names of this protein?
LIM and cysteine-rich domains protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May shuttle between the cytoplasm and the nucleus.
Protein: SAHH_PARXL
Sequence: MNAAVIDSKNSQDFIVADMSLADWGRKELNIAETEMPGLVQTREEYKVQQPLKGARIAGSLHMTIQTGVLIETLTALGADVRWASCNIFSTQDHAAAAIAKAGTPVFAFKGESLDEYWEFSHRIFEWPNGEFANMILDDGGDATLLLILGSKAEKDRSVISKPTNEEEVALYKSIERHLDADPTWYSTRLAHIKGVTEETTTGVHRLYQMEKEGRLPFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKADIFVTATGNYHVIGHDHMKAMRHNAIVCNIGHFDSEIDVASTRQYQWDNIKPQVDHIIFPDGKRVILLAEGRLVNLGCATGHPSFVMSNSFTNQTLAQIELFTQGNKYENKVYVLPKHLDEKVARLHLARIGANLTVLSDEQAGYIGVDKNGPFKPNHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_PSEPK
Sequence: MNSDLALLRLLQLASPGLPVGGFTYSQGLEWAVEAGWVRGVDSFAGWQREQVHDTLACLDWPVLARLYHACQAKDAEAFGHWSRFLLANRETAELRLEEQQRGAALARLLDGWQLGQAPAWRASLELTQLGGMAWLAAHWAIPLRQLALGHGFAWLEGAVMAGVKLVPFGQQAAQTLLRDLGADLPAALDQALALGDDQLGGGLPLLAIASSRHETQYTRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_SALHS
Sequence: MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDFKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVRCSAKTGVGVTDVLERLVRDIPPPQGDPDGPLQALIIDSWFDNYLGVVSLVRIKNGTMRKGDKIKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDILGAPVGDTLTSARNPAEKALPGFKKVKPQVYAGLFPVSSDDYESFRDALGKLSLNDASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTAKETIYVDSPSKLPPLNNIYELREPIAECHMLLPQAYLGNVITLCIEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINNERVDALALITHRDNSQSRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CH60_SHEHH
Sequence: MAAKEVLFGNDARVKMLAGVNVLANAVKVTLGPKGRNVVLDKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVTEGLKAVAAGMNPMDLKRGIDKAVIAAVAELKNLSQECSDTKAIAQVGTISANSDESIGEIIATAMERVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELESPFILLVDKKVSNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTAKRVIITKDDTTIIDGNGEETQIKARVAQIKIQAEESTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVASKIGEVEVLNEDQKHGVIIALRAMEAPLRQIATNAGEEGSVVANNVKNGTGNYGYNAGNDTYGDMLEMGILDPTKVTRSALQFASSIAGLMITTECMVADVKEDAADMGGMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHX2B_MOUSE
Sequence: MYKMEYSYLNSSAYESCMAGMDTSSLASAYADFSSCSQASGFQYNPIRTTFGATSGCPSLTPGSCSLGTLRDHQSSPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFRKQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPGQGWAPGPGPITSIPDSLGGPFASVLSSLQRPNGAKAALVKSSMF
What are the official names of this protein?
Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOA_CUPMC
Sequence: MQTALLKPKIIAVEPLGDHHAKVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTIDGVQEDVVNLLLNLKGVVFKLHNRDEVTVSLRKDGEGVVTAADIELPHDVEIINPGHVIAHLSAGGKLDMQIKVEQGRGYVPGNVRKFGDEASKVIGRIVLDASFSPVRRVSYAVESARVEQRTDLDKLVMNIETDGVISPEEAIRQSARILVDQLSVFAALEGTESAAEAASSRAPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLEK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RS12_CAMHC
Sequence: MPTINQLVRKERKKIIEKSKSPALKNCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGFEVISYIGGEGHNLQEHSIVLVRGGRVKDLPGVKYHIVRGALDTAGVAKRTVSRSKYGAKRPKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RPOZ_THISH
Sequence: MARITVEDCLTNMDNRFQLVLVAAKRARQLSMGHQPRVAEENDKPTVIALREIADGHVGREVLDEVVAEEHAAVSSRISEDEVRAEL
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: RL20_STRAW
Sequence: MARVKRAVNAHKKRRAILEAASGYRGQRSRLYRKAKEQVTHSLVYNYNDRKKRKGDFRQLWIQRINAAARANGMTYNRLIQGLKAANIEVDRKILAELAVNDAGAFAALVEVAQKALPSDVNAPKAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: CADH3_PIG
Sequence: KIAKYELFGHAVSENGASVEEPMNISIIVTDQNDHKPKFTQDVFRGSVLEGVLPGTSVMQVTATDEDDAINTYNGVVAYSILSQEPKDPHDLMFTVHRSTGAISVISSGLDRERVPEYTLTIQATDMDGDGSSTTATAIVEILDA
What is the function of this protein?
Cadherins are calcium-dependent cell adhesion proteins.  They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
What are the official names of this protein?
Cadherin-3, Placental cadherin, P-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ILVD_CALS4
Sequence: MRSDAVKKGVERAPHRSLLYALGLTDEELKRPIIGVANSKNEIIPGHIHLDKIAEAVKAGIRMAGGTPVEFSTIGVCDGIAMGHGGMKYSLGSREVIADSIEIMAMAHGFDGIVLIPNCDKIVPGMLMAAARLDIPAIVVSGGPMLAGICDGTTCDLSTVFEAVGALKAGKITEEEFYSIERNACPTCGSCSGMFTANTMNCLTEALGLGLPGNGTIPAVYSERIRLAKEAGMKIVELVERNITPSQILTKEAFVNAFSLDMALGGSTNTVLHLKAIAHEAGVDIPLEEINDISDRVPNLCKLSPAGKYHIEDLHFAGGVSAVLKELSKAGLLHLDALTVTGRTLGENIKDAKVRNRDVIRTIEDPYSKTGGIAILFGNIAREGAVVKASAVSPEMLRHEGPARVFDSEEEAIEAIYGGKIQKGDVVVIRYEGPKGGPGMREMLSPTSALAGMGLDKDVALITDGRFSGATRGASIGHVSPEAMEGGEIAIIEDGDIIEIDIPARKINVKLSDEEIKKRMANWKRPEPKIKKGYMARYTREVTSGSKGAVFREGGV
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.