PharMolix/UniProtQA huggingface dataset:
Protein: THII_AERHH
Sequence: MKFIIKLFPEITIKSKSVRQRFIKILQGNIRNVLRRFDDDARVRMDWDKLIVSSRNDQFREQAIEALACIPGIQAFLEVQASKFTDLHDIFEQVKAVWGDQLEGKTFCVRAKRHGKHEFSSLEVERYVGGGLNQHCVSNGVRLKNPDVKINLEIDGEELFIVSAIHQGLSGMPIATQEDVLSLISGGFDSGVASFQFIKRGCRVHYCFFNLGGAAHEIGVKQVAYHLWNRFGSSHRVRFTAVDFEPVVAEILEKIDNGQMGVVLKRMMMRAAAKVADEFQIPALVTGECVGQVSSQTLTNLNVIDRVTDKVILRPLITWDKPDIISEARRIGTLEFAETMPEYCGVISKKPTVKAELSRIEAEEENFDFAILDKVVAEARYLDIRRIGEETAAEVQEVETTAESGDNEVILDIRSMDEHNEKPLLVEGREVMHIPFFKLTTAFGDLPKEKTYLLYCDRGVMSKLQALYLKEKGFANVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNEP1_HUMAN
Sequence: MMRTQCLLGLRTFVAFAAKLWSFFIYLLRRQIRTVIQYQTVRYDILPLSPVSRNRLAQVKRKILVLDLDETLIHSHHDGVLRPTVRPGTPPDFILKVVIDKHPVRFFVHKRPHVDFFLEVVSQWYELVVFTASMEIYGSAVADKLDNSRSILKRRYYRQHCTLELGSYIKDLSVVHSDLSSIVILDNSPGAYRSHPDNAIPIKSWFSDPSDTALLNLLPMLDALRFTADVRSVLSRNLHQHRLW
What is the function of this protein?
Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2.  LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics.  May also indirectly regulate the production of lipid droplets and triacylglycerol.  May antagonize BMP signaling.
What are the official names of this protein?
CTD nuclear envelope phosphatase 1, Serine/threonine-protein phosphatase dullard.
What is the protein family that this protein belongs to?
Belongs to the dullard family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein.
Protein: LKA11_MANHA
Sequence: MGNKLTNISTNLKSSWLTAKSGLNRTGQSLAKAGQSLKTGAKKIILYIPKDYQYDTEKGNGLQDLVKAAEELGIEVQKEEGNDIAKAQTSLGTIQNVLGLTERGIVLSAPQLDKLLQKTKVGQAIGSAENLTKGFSNAKTVLSGIQSILGSVLAGMDLDEALQKNSNELTLAKAGLELTNSLIENIANSVKTLDAFGDQINQLGSKLQNVKGLSSLGDKLKGLSGFDKTSLGLDVVSGLLSGATAALVLADKNASTSRKVGAGFELANQVVGNITKAVSSYILAQRVAAGLSSTGPVAALIASTVSLAISPLAFAGIADKFNHAKSLESYAERFKKLGYDGDNLLAEYQRGTGTIDRSVTAINTALAAIAGGVSAAGRGSVIASPIALLVSGITGVISTILQYSKQAMFEHVANKIHNKIVEWEKNNHGKNYFENGYDARYLANLQDNMKFLLNLNKELQAERVIAITQQQWDNNIGDLAGISRLGEKVLSGKAYVDAFEEGKHLKADKLVQLDSANGIIDVSNSGKAKTQDILFRTPLLTPGTDDRERVQTGKYEYITKLNINRVDSWKITDGAASSTFDLTNVVQRIGIELDNAGNVTKTKETKIVAKLGAGDDNVFVGSGTTEIDGGEGYDRVHYSRGNYGALTIDATKETEQGSYTVNRFVETGKALHEGTSTHTALVGNREEKIEYRHSNNQHHAGYYTKDTLKAVEEIIGTSHNDIFKGSKFNDAFNGGDGVDTIDGKDGNDRLFGGKGDDIIDGGNGDDFIDGGKGNDLLHGGKGDDIFVHRQGDGNDIITDSDGNDKLSFSDSNLKDLTFEKVKHNLVITNSRKEKVTIQDWFREADFAKEVRNYKATKDEKIEEIIGQNGERITSKQVDDLIAKGNGKITQDELSKVVDNYELLKHSKNVTNSLDKLISSASAFTSSNDSRNVLVAPTSMLDQSLSSLQFARAA
What is the function of this protein?
Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture.  The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell (By similarity).  This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis.  It has also weak hemolytic activity.
What are the official names of this protein?
Leukotoxin, Lkt.
What is the protein family that this protein belongs to?
Belongs to the RTX prokaryotic toxin (TC 1.C.11) family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein.
Protein: LEUD_MYCA1
Sequence: MEAFHTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFASWRSDPSFVLNLSPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFGDIFRGNAGKAGLLAAEVSQDGVELLWKLIEQSPGLEITANLQDRNITAGTTVLPFKIDDHTAWRLLEGLDDIALTLRKLDRIESYEAAYPDWKPRTSPVA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TX2_ACAPA
Sequence: MNTTQVILFAVVLVLTVTVGQADEDSAETSLLRKLEEAEASMFGQYLEESKNSPEQRCAGENVPCDKDRPGDCCSRYECLKPTGYGWWYASYYCYKKKSG
What is the function of this protein?
Inhibits 31. 17% of Cav2. 1/CACNA1A current at 1 uM concentration.
What are the official names of this protein?
Omega toxin Ap2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 08 (Ltx-4) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPT_STRPQ
Sequence: MFGLKAKSTKKVFGGIPKHIGIIMDGNGRWAKKRLKPRVFGHKAGMDALQEVTITASELGVKVLTVYAFSTENWSRPQDEVSFIMNLPVTFFDKYVPVLHENNVKIQMIGETSRLPEDTLAALNAAIDKTKRNTGLILNFALNYGGRAEITSAVRFIAQDVLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFLPWQSAYSEFYFTPVLWPDFKKAELLKAIADYNHRQRRFGKV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: ATPL_STACT
Sequence: MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMSIMFIGIGLVEALPILGLVISFIVLFQ
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SCPA_STRPS
Sequence: MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVSTLQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLLGEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLTFSNILAKKKEEFAQNHTTILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELILVQEESFGDIYLMEKKEESQVPQS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: RR19_PETHY
Sequence: MTRSLKKNPFVANHLLNKIDKLNT
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TEAB_HALED
Sequence: MTDEEEAEKHYHSGLPGILGTIDTLISKLEAIILALGVLLMATNTVANVIGRFALGESLFFTGEVNRILIIMITFAGIGYAARHGRHIRMSAIYDALPVGGRRALMIVISLFTSLVMFFLMYYSVHYVLDLYDKGRILPALGFPIFIIYVWVPLGFLITGIQYLFTAIKNLTSRDVYLSTSVVDGYKDTETEV
What is the function of this protein?
Part of the tripartite ATP-independent periplasmic (TRAP) transport system TeaABC involved in the uptake of ectoine and hydroxyectoine in response to osmotic upshock.  Probably functions as a recovery system for synthesized ectoine that leaks out of the cell.
What are the official names of this protein?
Ectoine TRAP transporter small permease protein TeaB.
What is the protein family that this protein belongs to?
Belongs to the TRAP transporter small permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COQ4_CANDC
Sequence: MLKSTVSNTRIKCCRIDQRRNYLFTALASSALGSFLWSKNNVLASKMENGELHYHDPNLTFNKKLFNGKPPFERRAPDYPGHVPLYNFEKVLMFLGSSMGAFFHPEENKYIVALGESTAITPILQHLRHKMLSDPVGRTILREKPRMTSDSLNLTYLRSLPDNTIGKNYVNWLDKENVSPDTRVPVRYIDNEELAYIYQRYRECHDFYHAITGLPIIIEGEIAVKVFEFANIGIPMSGLGALFAPLRLKPSQRQRLREIYYPWAIKNGLFSKPLINVYWEKILEKDVNEFRQEMGIQQPPDLRNMRKEYFAKKKLEKQLQGRK
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y1490_ARATH
Sequence: MLGYKCLHWNNLIDLPPLKDPETFSLPSSIPHWPPGQGFGSGTINLGKLQVIKITDFEFIWRYRSTEKKKNISFYKPKGLLPKDFHCLGHYCQSDSHPLRGYVLAARDLVDSLEQVEKPALVEPVDFTLVWSSNDSAENECSSKSECGYFWLPQPPEGYRSIGFVVTKTSVKPELNEVRCVRADLTDICEPHNVIVTAVSESLGVPLFIWRTRPSDRGMWGKGVSAGTFFCRTRLVAAREDLGIGIACLKNLDLSLHAMPNVDQIQALIQHYGPTLVFHPGETYLPSSVSWFFKNGAVLCEKGNPIEEPIDENGSNLPQGGSNDKQFWIDLPCDDQQRDFVKRGNLESSKLYIHIKPALGGTFTDLVFWIFCPFNGPATLKLGLVDISLISIGQHVCDWEHFTLRISNFSGELYSIYLSQHSGGEWIEAYDLEIIPGSNKAVVYSSKHGHASFPRAGTYLQGSTMLGIGIRNDTARSELLVDSSSRYEIIAAEYLSGNSVLAEPPWLQYMREWGPKVVYDSREEIERLVNRFPRTVRVSLATVLRKLPVELSGEEGPTGPKEKNNWYGDERC
What are the official names of this protein?
Hypothetical protein At1g04090.
Protein: RS15_METC4
Sequence: MSITAERKTALIKDYAKGNKDTGSPEVQIAILTERITNLTAHFKTHGKDNHSRRGLLKLVSQRRSLLDYLKRKEEARYRTLIERLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DCUC_SHIFL
Sequence: MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAIMGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAYLTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELMVPGTAAAVTGK
What is the function of this protein?
Responsible for the transport of C4-dicarboxylates during anaerobic growth.  Catalyzes the uptake of fumarate coupled to the export of succinate.
What are the official names of this protein?
Anaerobic C4-dicarboxylate transporter DcuC.
What is the protein family that this protein belongs to?
Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABPI_BOVIN
Sequence: MAFDGTWKVDRNENYEKFMEKMGINVVKRKLAAHDNLKLIITQEGNKFTVKESSTFRSIEIIFELGVTFNYSLADGTELSGAWALEGDKLVGKFKRLDNGNALNTVREIIGGEMVQTYTYEGVEAKRIFKKE
What is the function of this protein?
FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.  FABP2 is probably involved in triglyceride-rich lipoprotein synthesis.  Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids.  FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity).
What are the official names of this protein?
Fatty acid-binding protein, intestinal, Fatty acid-binding protein 2, Intestinal-type fatty acid-binding protein, I-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y023_RICCN
Sequence: MLCFEAICLGAINSSSKNFTCVKEFVRAYPELTNKITNEHPEYFIDGSILRICVNDKAILNKLLASG
What are the official names of this protein?
Uncharacterized protein RC0023.
Protein: RSMA_PARD8
Sequence: MRLVKPKKALGQHFLKDLQIAQRIADTLDTFKSLPVLEIGPGMGVLTQFLLEAGHDLTVVELDMESVDYLNQNFPDLKGRIIAEDFLKLDLSKLFPGQFCVIGNYPYNISSQIFFKVLDYKDQIPCCSGMLQKEVAERLAAGPGSKTYGILSVLLQAWYDVEYLFTVSEKVFDPPPKVKSAVLKMTRNDRKELGCDEKLFKTVVKTSFNQRRKTLRNSMKPLLGKDCPDYALPIFDKRPEQLSMEQFVELTLISQKHLEKQAGDVL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCAD1_PONAB
Sequence: MNGRADFREPNAEVPRPIPHIGPDYIPTEEERRVFAECNDESFWFRSVPLAATSMLITQGLISKGILSSHPKYGSIPKLIFACIMGYFAGKLSYVKTCQEKFKKLENSPLGEALRSGQARRSSPPGHYYQKSKYDSNVSGQSSFVTSPAADNIEMLPHYEPIPFSSSMNESAPTGITDHIVQGPDPNLEESPKRKNITYEELRNKNRESYEVSLTQKTDPSVRPMHERVPKKEVKVNKYGDTWDE
What is the function of this protein?
Maintains stem cell potency (By similarity).  Increases STAT3 phosphorylation and controls ERK phosphorylation (By similarity).  May act as a scaffold, increasing STAT3 recruitment onto endosomes (By similarity).
What are the official names of this protein?
OCIA domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the OCIAD1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: MURD_HAEIE
Sequence: MNAYQNKNITIIGLGKTGLSCVDYLLSQQANIRVIDTRKKPTGIDKLPQNIPLHTGSLNQEWLLESDMIVISPGLAVKTPEIQTALKAGVEVIGDIELFCRAATKPIVGITGSNGKSTVTTLVYEMAKAAGVKVGMGGNIGIPALSLLNEDCELYVLELSSFQLETTYSLKAAAATVLNVTEDHMDRYMDLEDYRQAKLRIYHNAEVGVLNNEDKLTFGEGENQARQTVSFAENSADYWLKTENGKQYLMVKDEVILPCEEATLVGRHNYMNILAATALAQAVGINLDAIRTALRHFKGLDHRFQLAHQANGVRWINDSKATNVGSTVAALSGLYVEGKLHLLLGGDGKGADFSELAELINQPHIICYCFGRDGALLAKLSSQSYLFETMEQAIAFLRPTLQSGDMVLLSPACASLDQFASFEKRGEEFTRLAQCLA
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_SERP5
Sequence: MTNSYLAFPKFDPVIFSIGPVSLHWYGLMYLVGFVFAMWLAVRRANKPGSGWTKDEVENLLYAGFLGVFVGGRVGYVLFYNLPLFMENPLYLFKVWDGGMSFHGGLMGVILVMFWFARRTKRTFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVTTDTPWAMLFPSSRAEDVALAAADPKLLPILNQYGVLPRHPSQLYELLLEGVVLFIILNLFIRKPRPMGAVSGLFLIGYGAFRIIVEAFRQPDAQLGLFDGVISMGQILSVPMVVAGIIMMIWAYRRRPQQQLS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPX_STAA8
Sequence: MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAMTELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTNILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYDEQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: AROC_STRP4
Sequence: MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYGRGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRKITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANHVVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVVETVVGGVPVGXGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEILWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RUVC_RHILW
Sequence: MQNTIRIVGIDPGLRRTGWGIIDTLGNSLRFVASGTVTSDGDMDLASRLCQLHDGLAEVVHTYKPDEAAVEQTFVNKDAVATLKLGQARGIAMLVPARAGLRVSEYAPNAVKKAVIGVGHGEKHQIHMMLKILMPKVEFKGDDAADALAIAICHAHNRGSNRMREALAG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: UBIG_SALTI
Sequence: MNTEKPSVAHNVDHNEIAKFEAVASRWWDLKGEFKPLHRINPLRLGYITERSGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAKKA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: Y4UB_SINFN
Sequence: MTIDIKDISEKDRNTVLHPFTQLKDFATGKLREPTIVETGKGIRIQDARGNQLIDGFAGLYCVNVGYGRTEVAEAISRQAYRLAYYHSYAAHTTDELAILSDRLVKMAPGKMSKVFYGMSGSDANETQAKLVWYYNNLRGKPTKKKIISRERGYHGCSVVSGSMTGMSFYHDHMDLPLPQICHTGVPHHYWGANPGETEREFSARRAAELDEMIETLGPDNVGAFIAEPVLGTGGITPPPEGYWEAIQAVLKKHDVLLIADEVITGFGRTGSMFGSQHYGIEPDLITVAKGLTSAYFPLSASIVGEKVYKVLEDGADRVGAFSHGYTYSGHPIGAAAANAVLDIVEKEDLPGNAREVGGYFQAQLKEKFAQLPIVGEVRGVGLMGAIEFVGDRENKKRFDPLLKVGARVSKAARDRGLIARAMPHGDILGFAPPLVTTKEEVDEIVAMAEKAVRSVMDELVRDGQKL
What are the official names of this protein?
Uncharacterized aminotransferase y4uB.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: YHBX_ECOLI
Sequence: MTVFNKFARTFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFFVLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDPDEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQFAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVRDTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVPLSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETVYVRGFDELLLPHLSQALQQNTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDACYDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHVPMFIWYSPVLGDGVDRTTENNIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDSRVVDANHDVFDYVMLRKEFTEDKQGNPTPEGQG
What is the function of this protein?
Probably does not transfer phosphoethanolamine to lipid A.
What are the official names of this protein?
Putative transferase YhbX.
What is the protein family that this protein belongs to?
Belongs to the phosphoethanolamine transferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL22_METBF
Sequence: MARINYSVKEDPETTSKAMGSELHISPKKSREVCCKIKGMKVPEARKFLEDVIALKQAVPFKRHHDGSGHRKGPMAAGRYPVSASKEILKILRNAESNAEYKGLEPANMYITHAAIQRGRVIRGFMPRARGRATPKDTETVNIEMILSEVR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: YR01_CAEEL
Sequence: MFGKILTTSLLIAMTFAAPSTEEGKSSKRRQYIAPLAGAAQVPRNPLFFAAPALPVAAAPALVRPAFAPVPVAAAPAFAPVPVAAPMVRPMLQQPAIVAPVAPVVAPVGQCPGGPSLPIECDPKRPWPQCPPQSYCYATNSVDIGPYFCCPIWSTYGAAWRPATPFYNYVPPVPANWPDVARMTANWPAAAVAMPLKARKQQKNEGDDEETEDEQKIGSAIDGWVERQAKL
What are the official names of this protein?
Uncharacterized protein T25E4.1.
Protein: RS5_LISMO
Sequence: MPEQIDGNKLDLEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGHVGFGTGKAQEVPDAIRKAVEDAKKNMVLVPTVDTTIPHTVVGHFGGGEILLKPASAGSGVTAGGPVRAVLELAGVADVSSKSLGSNTPINMVRATIDGIKQLKNAEDVAKLRGKTVEELLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.