PharMolix/UniProtQA huggingface dataset:
Protein: SAP_RAT
Sequence: MYALALLASLLVTALTSPVQDPKICSGGSAVVCRDVKTAVDCRAVKHCQQMVWSKPTAKSLPCDICKTVVTEAGNLLKDNATEEEILHYLEKTCAWIHDSSLSASCKEVVDSYLPVILDMIKGEMSNPGEVCSALNLCQSLQEYLAEQNQRQLESNKIPEVDLARVVAPFMSNIPLLLYPQDRPRSQPQPKANEDVCQDCMKLVTDIQTAVRTNSSFVQGLVDHVKEDCDRLGPGVSDICKNYVDQYSEVAVQMMMHMQPKEICVMVGFCDEVKRVPMRTLVPATEAIKNILPALELTDPYEQDVIQAQNVIFCQVCQLVMRKLSELIINNATEELLIKGLSKACSLLPAPASTKCQEVLVTFGPSLLDVLMHEVNPNFLCGVISLCSANPNLVGTLEQPAAAIVSALPKEPAPPKQPEEPKQSALRAHVPPQKNGGFCEVCKKLVIYLEHNLEKNSTKEEILAALEKGCSFLPDPYQKQCDEFVAEYEPLLLEILVEVMDPSFVCSKIGVCPSAYKLLLGTEKCVWGPGYWCQNSETAARCNAVDHCKRHVWN
What is the function of this protein?
Saposins are specific low-molecular mass non-enzymatic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
What are the official names of this protein?
Prosaposin, Sulfated glycoprotein 1, SGP-1.
What are the subcellular locations of this protein?
Lysosome. SUBCELLULAR LOCATION: [Prosaposin]: Secreted. Note=Secreted as a fully glycosylated 70 kDa protein composed of complex glycans.
Protein: SYT_BURCM
Sequence: MVSIRLPDGSVRQYEHPVTVAEVAASIGPGLAKAALGGKLDGELVDTSTVIDRDAALAIITDKDADGLDIIRHSTAHLLAYAVKELYPDAQVTIGPVIDNGFYYDFSYNRPFTPEDLEKIEKRMQEIAKKDEPVTRRVVSRDEAAGYFRSIGEKYKAEIIESIPQTDEIKLYSHGGFTDLCRGPHVPSTGKLKVFKLMKVAGAYWRGDSKNEQLQRIYGTAWTKKEDQDQYLHMLEEAEKRDHRKLGKQLDLFHMQEESPGMVFWHPKGWALWQQVEQYMRRRVNDAGYLEIKTPMIMDRSLWEASGHWQNYRENMFTTESEKRDYAIKPMNCPGHVQVFKHGLRSYRDLPLRYAEFGSCHRNEASGALHGLMRVRGFVQDDAHIFCTEEQFIAESIAFNTLAMSVYKDFGFEHIDIKLSLRPEQRAGTDETWDRAEQGLRDALTACGLSWEELPGEGAFYGPKIEYHIKDALGRSWQCGTLQLDMVLPERLGAEYVAEDNSRRRPVMLHRAIVGSMERFLGILIEHHAGAMPAWLAPFQAVVLNIAESQVEYAHSLTQTLQKQGVRVAGDLRNEKISYKIREHTLEKVPYLLVVGDKERDAQTVAVRARGGVDLGVMPIEAFVERLQEDLRSFK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAL1_YEAST
Sequence: MFTSKPAFKIKNKASKSYRNTAVSKKLKEKRLAEHVRPSCFNIIRPLKKDIQIPVPSSRFLNKIQIHRIASGSQNTQFRQFNKTSIKSSKKYLNSFMAFRAYYSQFGSGVKQNVLSSLLAEEWHADKMQHGIWDYFAQQYNFINPGFGFVEWLTNNYAEVRGDGYWEDVFVHLAL
What is the function of this protein?
Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion.  Transcriptional coactivator that, in alpha-cells, binds cooperatively with MCM1 and STE12 to a DNA sequence termed the QP' element, to activate the transcription of alpha-specific genes.
What are the official names of this protein?
Mating-type protein ALPHA1, MATalpha1 protein, Alpha-1 activator.
What is the protein family that this protein belongs to?
Belongs to the MATALPHA1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYC_SHEB9
Sequence: MLKIYNSITRQKQEFKPITPGKIGMYVCGVTIYDLCHIGHGRTFVSFDMIVRYLRYAGYEVNFQRNITDVDDKIIKRANENNESCEALTERLIGEMHQDFDALNMLRPDFEPRATLHIAEIIDMVELLLARGHAYVASDGDVLFSVASYPDYGRLSGQNLDQLQAGARVEVDETKQNPMDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSKHLGLHFDIHGGGSDLQFPHHENEIAQSCCAHDTPYVNYWMHTGMVMVDREKMSKSLGNFFTIRDVLGHYDAETVRYFLLSGHYRSQLNYSEDNLKQARSALERLYTAIKDVDLTVAAAPAEEFIAKFKAAMDDDFNTPEAYSVLFDMVREINRLKLTDMAQASALAVTLKQLADVLGLLSQEPEAFFQGGGSDDEVAEIEALIVERNRARTEKDWAAADVARNRLNELGVELEDGPSGTTWRKK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_IDILO
Sequence: MNKVLIAAAGTGGHIFPALAVAEQMRDNGWQVDWLGTQEGRLESRVIPAANFPLHSISMTGVRGHGLKRKLFMPFTLAKAVLQCRRLLKTLQPQVVATFGGYVCAPMGLAAKLLGIPLVVHEQNAIPGMTTRLLAPRANKVMLGLPVALPQWQQYPVVGNPLRKGLLAQAAEQTEKSNTDGALNILVVGGSLGAQVLNEAVPEAVKALEGVELNVLHQCGAEREATTEKAYLGASVLKTLKVTEFIEDMGDAFKNADLVICRAGALTISELAVMGVASILVPLPHAVDDHQSANAKVLESRGAAVLLPQTEVVEGALKQQLKRLLHDRQQLWTMARFARQCAMPEATQRLVNECMEYRQSDD
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS10_STRPC
Sequence: MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGAKVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: MED31_ENCCU
Sequence: MSGSRFERELEFVQLLCNPDYLRWLTREGHFESEEFRSYLRYLEYWRSPEYSRFLTYPQCLAVLEHLNSENINDMLSDENFFLALGEQQYFIWLNKHKEGWNK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNFB_VIBC1
Sequence: MSTILIAIIALAALAAVFGAILGFASIRFKVEADPIVDQIDSILPQTQCGQCGYPGCRPYAEAIANGDQINKCPPGGQATIEKLADLMGVEAEESAHDLDSKVKTVAFIHEDMCIGCTKCIQACPVDAIVGGTKALHTVIKDECTGCDLCVAPCPTDCIEMIPVETTTESWKWKLNAIPVVNITDAANAANVTDSIK
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rnf electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: GAG_HV1B1
Sequence: MGARASVLSGGELDRWEKIRLRPGGKKKYKLKHIVWASRELERFAVNPGLLETSEGCRQILGQLQPSLQTGSEELRSLYNTVATLYCVHQRIEIKDTKEALDKIEEEQNKSKKKAQQAAADTGHSSQVSQNYPIVQNIQGQMVHQAISPRTLNAWVKVVEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRVHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQGPKEPFRDYVDRFYKTLRAEQASQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNTATIMMQRGNFRNQRKMVKCFNCGKEGHTARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSYKGRPGNFLQSRPEPTAPPFLQSRPEPTAPPEESFRSGVETTTPPQKQEPIDKELYPLTSLRSLFGNDPSSQ
What is the function of this protein?
Plays a role in budding of the assembled particle by interacting with the host class E VPS proteins TSG101 and PDCD6IP/AIP1.
What are the official names of this protein?
Gag polyprotein, Pr55Gag.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group gag polyprotein family.
What are the subcellular locations of this protein?
[Gag polyprotein]: Host cell membrane; Lipid-anchor. Host endosome, host multivesicular body. Note=These locations are probably linked to virus assembly sites. The main location is the cell membrane, but under some circumstances, late endosomal compartments can serve as productive sites for virion assembly. SUBCELLULAR LOCATION: [Matrix protein p17]: Virion membrane; Lipid-anchor. Host nucleus. Host cytoplasm. SUBCELLULAR LOCATION: [Capsid protein p24]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p7]: Virion.
Protein: SWD3_SCHPO
Sequence: MDSTAQQFPLNHDLQVQKDQKGVVEEDEEQIHKRIRNYESHSGFSEYCTLFGHEKSVTCVSVSPNKRWIATSSSDGTIKIWSALTFRLECTLFGHYRGISQVKWATGSKYLASASDDKTIRIWDFEKRCSVRCLKGHTNYVSSIDFNPLGTLLVSGSWDETVRIWNLQDGTCLRMLPAHSEPIISVSISADGTLCATASYDGMARIWDVLSGQCLKTLVEPINVPLSNLQFTENRKYLLVSNLNSQIRLWDYRRNRVVRIFDSHVNTRYSMSWDCYSSKNIPKNTEALPNNDSSYPDDAESFMHDAYLLIPSEDGTIQITDPSTKIIIDDSIRHSDDPETSLLNVTSLGPFIITSGTDPYVRVWAPSLLLSKHEKDGFSP
What is the function of this protein?
The Set1 complex specifically methylates 'Lys-4' of histone H3.
What are the official names of this protein?
Set1 complex component swd3, Set1C component swd3, COMPASS component swd3, Complex proteins associated with set1 protein swd3.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRC_BACC3
Sequence: MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQVGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: GLMS_GLUOX
Sequence: MCGICGIVGHQPASPIAFEALRRLEYRGYDSAGIATLTASGDIERRRAAGKLDNLEHVLKEHPLPGTTGIGHTRWATHGAPTENNAHPHEAGRVAIVHNGIIENFAELKKELEAKGRVFRTETDSETVAHLVDDYLGQGLEPREAAFAAIKRLEGAYAIAMIFKDHEGLLIGARHGAPLAVGYGNGEMFLGSDSIALAPMARKMTYLEDGDWCELTPDHVTIFDMTGAEVSRPVQDLTFMAGQVGKDGYRHYMEKELHEHPVAIGQTLKRITDPASKRIALPEMPFDPAQVPRITITACGSAYYAGMVGRYWLESLARIPVEIDVASEMRYREPPQPDKGVALLISQSGETADTLGVLRSLKKAGQSIVSVLNVEHSTMGRESDLVLGMDAGPEISVASTKAFTAQLSVLAALAIDFARARGTMDQAREERLTASLLDLPSRAAEVFTRTKDIQAMAAVVAQARDVLYLGRGICTPIAFEGALKLKEISYIHAEAYAAGELKHGPISLIDQTVPVVAIAPSTILFDKTLSNLQEAKARGGRILAFTDAEGAKRLEGVAEQVVIMPDVDAFVAPILYAIPVQMLAYEVALLKGTDVDQPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETN_VITVI
Sequence: MDIVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: PRS7_MACFA
Sequence: MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  PSMC2 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
What are the official names of this protein?
26S proteasome regulatory subunit 7, 26S proteasome AAA-ATPase subunit RPT1, Proteasome 26S subunit ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Colocalizes with TRIM5 in cytoplasmic bodies.
Protein: THIO_CHLCV
Sequence: MVKVVSAENFNSFIATGLVLIDFFAEWCGPCKMLTPVLESLEAEVSSVLIGKVNIDDHPAPAEQYGVSSIPTLILFKDGKEVDRVVGLKDKDSLIRLINQHS
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: RS13_HELPH
Sequence: MARIAGVDLPKKKRVEYALTYIYGIGLKSSREILEAVGISFDKRVHELSEDEVSSIAKKIQQSYLVEGDLRKKVQMDIKSLMDLGNYRGIRHRKGLPVRGQTTKNNARTRKGKKKTVGSK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PROA_BACC3
Sequence: MNEVLAKGKRAKEVAMNLVLKSTSQKNEALAAIAERLIVETAYILEENKRGIEEGKAKGFSDSLLDRLMLTEQRIVDMTEGIKQLIELRDPVGECVSAWERPNGLSIQEMRVPLGVVGMIYEARPNVTVDAATICLKTGNAVILRGSSSAIHSNKAIVAVIHRALKQTSLPQESVQLIEDTTRDSAKQLFTMNDYLDVLIPRGGKQLIDTVVREASVPVLETGAGNCHVFIDETADKQMAFDIIINAKTQRPSVCNAIETIVLHEKWAEQYGSELFSSLKKRGVELRGDQKALAMDSSIVLASEEDWWTEFLSLTLAVKLVSSIEEAIHHINTYGSMHSEAIISENEENVSKFFVSVDAAALYHNASTRFTDGSEFGFGAEIGISTQKLHVRGPMGLPALTSTKYVIRGNGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CLOB8
Sequence: MVHPVQVGKRTRMSFGKVNDVTEMPNLIEVQLDSYEWFLREGLHEVFDDINPITNFTGNLVLEFVDYKLDMENIKYSVEECKERDATYAAPLKVSIRLQNNETGEIKEQEVFMGDFPLMTEQGTFVINGAERVIVSQLVRSPGVYYNYSIDKSGKKLYSSTVIPNRGAWLEYETDSNDVIYVRIDKTRKLSISILARAMGLGSDQELLDFFGEEERFRASIEKDNTKTKEEALLEIYKRLRPGEPPTVDSAISLIDTLFFDAKRYDLSRVGRYKFNKKLALNLRIANQVAATDIVNPQTGEIMVEKGQKISRLVAEEIQNAGVKSVDVLIEDKVIRVISNNFVDLKKQVSFDISDLGIKELVHYPTLKEILDNFSDEASIKEEIKKNISKLIPKHIIRDDIFATISYELGLTYGIGYVDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEAITPQMLINIRPVAAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATFAKVNEYGFIETPYRIVDKENGRATDEIRYFTADEEDQCLIAEAKEPMDENGHFINKKVRVRHLEDILVVPTTDVDLIDVSARQIVSVATAMIPFLENDDASRALMGSNMQRQAVPLLSPQAPIVGTGIEFKAAVDSGVLPKAKNAGVVTYVSGSEIRVKRDSDGGTDVYKLLKFKRSNSGTCINQRPIVDTGEIVYKNQVIADGPSTDLGEIALGKNIRMGFITWEGYNYEDAMLISEELVREDVFTSMHIEEYECEARDTKLGPEEITRDIPNVSDDALKDVDDRGIIRIGAEVRSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGEAGIIVDIKVFTRENGDELNPGVNELVRCYIAQKRKISVGDKMAGRHGNKGVISRILPEEDMPFLPDGRPLQICLNPLGVPSRMNIGQVLEVHLGWAASHLGWHIATPVFDGATQPEITECMIKAGFREDAKTILYDGRTGEPFDNPVTVGIMYILKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRVKTYEAIVKGENIPEPGVPESFKVLIKELQALCLDIKVLNDEHEEVTLKEFVDEDMANLEVNIEGTEEIMVPEPDVLDDDSYDQNNDEDIDEIDYDESVDIADLETELELDDFNDEH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: NANK_ECO5E
Sequence: MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLGQLTDLPTIAINDAQAAAWAEYQALEGDITDMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADAKTIFMRAGQGDEQAQQLIHRSAHVLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: VNS2_DSDNV
Sequence: METPTEKPIVLPDLIKVIYESHQQDHPLVNNVAWWQLHLENVNGHMEDEEQWPALQKNLKKTFNTWQRNWKKWAINSLDTLLGKVLNLPAHISAMSLSYEIFSSVINVWTSCVSTEEVDETDCSDFLKKETTSTSSTIALTPIGVAGTSGLVKSSPSELFRKLANPSNISGSLNEPTGMMSSSISLYENGESVQYTLEEKVGKYRVTMNVYDGPESLKKEKWYQAPIARITMSVNNKSTKLAVDQMLAVLTEDFMKRKPTRQGNSLTYGKRQKRY
What are the official names of this protein?
Non-structural protein NS2.
Protein: ARGD_ARATH
Sequence: MASLSQITLPRAPSSEIGLLRRRLERPIIRTRIGFNGRIASVLTNAGDQAVSVKASVSQKVIEEEAKVIVGTYARAPVVLSSGKGCKLFDPEGKEYLDCASGIAVNALGHGDPDWLRAVTEQAGVLAHVSNVYYTIPQIELAKRLVASSFADRVFFCNSGTEANEAAIKFSRKFQRFTHPEDKEVATGFIAFTNSFHGRTLGALALTSKEQYRTPFEPIMPGVTFLEYGNIQAATDLIRSGKIAAVFVEPIQGEGGIYSATKEFLQSLRSACDAAGSLLVFDEVQCGLGRTGLMWAYEAFGVTPDIMTVAKPLAGGLPIGAVLVTEKVAETINYGDHGSTFAGSPLVCSAAIAVMDKVSKPSFLSSVSNKGRYFRDLLVKKLGGNSHVKEVRGEGLIIGVELDVPASSLVDACRDSGLLILTAGKGNVVRIVPPLVISEEEIERAVEIMSQNLTALD
What is the function of this protein?
Involved in the biosynthesis of citrulline (By similarity).  Essential gene that modulates defense response to pathogenic bacteria, conferring susceptibility and repressing salicylic acid (SA) accumulation.
What are the official names of this protein?
Acetylornithine aminotransferase, chloroplastic/mitochondrial, ACOAT, Acetylornithine transaminase, AOTA, Protein HOPW1-1-INTERACTING 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.
Protein: RL7_CERSP
Sequence: MADLNKLAEDIVGLTLLEAQELKTILKDKYGIEPAAGGAVMMAGPAAGAAAPAEEEKTEFDVGLTDAGANKINVIKEVRAITGLGLKEAKDLVEAGGKVKEAVAKADAEAMKKKLEEAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12, RA.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: KV621_HUMAN
Sequence: MLPSQLIGFLLLWVPASRGEIVLTQSPDFQSVTPKEKVTITCRASQSIGSSLHWYQQKPDQSPKLLIKYASQSFSGVPSRFSGSGSGTDFTLTINSLEAEDAATYYCHQSSSLP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 6-21.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: RS4_STRZP
Sequence: MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MNME_CALS4
Sequence: MEFDTIAAISTFPGEAGIGIVRISGDEALEIISKIFRPFRKKDIKSVKSHTIHYGHIVDPETGEVYDEVLVTVMRKPNTYTREDVVEINCHGGIVVSSKILELVLKHGARLAEPGEFTKRAFLNGRIDLSQAEAVIDIITSKTMLANRYAQKQLAGVLGQKMKDLKNKIMELLSHLLALIDFPEEDVEELEREEIKRRAKDILNDIEYLIASSESGRIIREGLKTAIIGKPNVGKSSLLNALLKQNRAIVTDIPGTTRDVIEEYMNIKGIPIKLIDTAGIRHTDELVEKIGVEKSKEVLAEADLILFVLDASRDLTKEDYEIFDILSGKNIIFVLNKVDLPKKIDEEELKKLVGNGIIVEVSTVERTGLDKLESEIYNLVFKGKVSATEEEIITNARHREVLINAKKHMESVIEAIEKGYSEDLITIDVNGALNEIGKITGETATEDVINQIFERFCVGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN_LACE2
Sequence: MTDIKSLNYDELVTYMAGLGEKKFRAGQLYQWMHEKLADSFDECTNLSNALRQKLKETSEYVCLEPVRVQHSKLDGTEKYLFRLSDGNYVESVLMKYHHGNSVCISSQVGCRMGCRFCASTLNGKVRDLRPSEMLDQIYRIQKITGERVSNVVVMGSGEPMDNYDNLIKFIELLNDERGLNISQRNITVSSCGIVPKLKELADLKLQITLAISLHAPNDELRKTMMPIANKYSIEEIMDVCRYYIECTGRRISFEYSLVKGVNDSMECAKQLIELVKGMNCHINLIPVNPIKERDYKQTGKEEVYAFKNKLEKNGINVTIRREMGRDIDGACGQLRNKYMEDIDESDGGY
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.