PharMolix/UniProtQA huggingface dataset:
Protein: NADA_ECO24
Sequence: MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQSIAEALEQEGSNHEVHVDERLRERALVPLNRMLDFAATLRG
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_GLOVI
Sequence: MLAKRIVPCLDVKAGRVVKGVNFVGLRDAGDPVELAKLYNDQGADELVFLDIAATHEERAILIDVVYRTAEQVFIPLTVGGGIGDLDTIQALLDAGADKVSINSAAVRDPELIARAGERFGAQCIVLAIDARARAGGAGWEVYVRGGRTPTGLDAVAWAVEGERRGAGEILLTSMDADGTRAGYDLALTRAVAEAVQLPVIASGGAGNCEHIRTALTEGAAQAALLASLLHYGELTVEQIKAHLAAHGVPVRRG
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EVA1A_HUMAN
Sequence: MRLPLSHSPEHVEMALLSNILAAYSFVSENPERAALYFVSGVCIGLVLTLAALVIRISCHTDCRRRPGKKFLQDRESSSDSSDSEDGSEDTVSDLSVRRHRRFERTLNKNVFTSAEELERAQRLEERERIIREIWMNGQPEVPGTRSLNRYY
What is the function of this protein?
Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
What are the official names of this protein?
Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166.
What is the protein family that this protein belongs to?
Belongs to the EVA1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein.
Protein: MNMA_NOSP7
Sequence: MKKVVVGLSGGVDSSTAAAILHHQGYEVIGLTLWLMKGKGQCCSEGMIDAADLCEQLGVPHQIVDIRDLFQTHIVDYLVTGYSAGITPLPCSQCNKTVKFGPMVQYAREELGCDRIATGHYARISYDEATGRYQLLRAIDRNKDQSYFLYDLSQDLLAATIFPLGELEKTDTRRIATEYGLKTADKPESQDLCLVESNGSMRAFLDKYLAPKSGDIVDTTGKILGQHDGVHHYTIGQRKGLGIAAAEPLYVIELDAENNKVVVGDRTKVTQPECTVNRVNWVSIAEPSTPIHAEVQIRYRSTPTPVTVIPLENSRVRLVFDEPQFSITPGQAAVWYDGEKVLGGGIIEQFS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_MEASI
Sequence: MSPQRDRINAFDKDNPHPXXXXXXXXXXXXXXXRPYVLLAVLFVMFLSLIGLLAIAGIRFHRAAIYTAEIHKSLSTNLDVTNSIEHQVKDVLTPLFKIIGDEVGLRTPQRFTDLVKFISDKIKFLNPDREYDFRDLTWCINPPERIKLDYDQYCADVAAEELMNALVNSTLLETRTTNQFLAVSKGNCSGPTTIRGQFSNMSLSLLDLYLSRSYNVSSIVTMTSQGMHGGTYLVGKPNLSNKGSELSQLSMYRVFEVGVIRNPGLGAPVFHMTNYFEQPVSNDLSNCMVALGELKLAALCHGEDSITIPYQGSGKGVSIQLVKLGVWKSPTDMQSWVPLSTDDPVIDRLYLSSHRGVIADNQAKWAVPTTRTDDKLRMETCFQQACRGEVQALCEDPEWAPLKDGRIPSYGVLSVDLSLTVELKIKIASGFGPLITRGSGMDLYRSNHNNVCWLAVPPMKSLALGVVNTLEWMPGFKVGPYLFTVPIKEAGEDCHAPAYLPAEVDGDVKLSSNLVILPGQDLQYVLATYDTSRVEHAVVYYVYSPGRSFSYFYPFRLPIKGVPIELQVECFTWDQKLWCRHFCVLADSESGGHITHSGMVGMGVSCTVTREDGTNCR
What is the function of this protein?
Attaches the virus to cell receptors and thereby initiating infection.  Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.  May use human CD46 and/or SLAMF1 as receptors for viral entry into the cell.  The high degree of interaction between H and MCP/CD46 results in down-regulation of the latter from the surface of infected cells, rendering them more sensitive to c3b-mediated complement lysis (By similarity).
What are the official names of this protein?
Hemagglutinin glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. Non-sialidase subfamily.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: NC2A_RAT
Sequence: MPSKKKKYNARFPPARIKKIMQTDEEIGKVAAAVPVIISRALELFLESLLKKACQVTQSRNAKTMTTSHLKQCIELEQQFDFLKDLVASVPDMQGDGEDNHTDGDKGPRRGRKPGSSGRKNGGTGSKSKDKKLSGTDSEQEDESEDTDTDGEEETPQAPPQASHPPAHFQSPPTPFMPFTSPLPLPPAPPGPSAPEAEDEEDYDS
What is the function of this protein?
The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes.  This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP.  Can bind to DNA on its own (By similarity).
What are the official names of this protein?
Dr1-associated corepressor, Dr1-associated protein 1, Negative cofactor 2-alpha, NC2-alpha.
What is the protein family that this protein belongs to?
Belongs to the NC2 alpha/DRAP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRS37_BOVIN
Sequence: MKFTFCLTVLAGTFFSAHSSVQKDDPSPYLVYLKSHFNPCVGVLIKSNWVLAPAHCYLPNLKVMLGNLRIRIRDGTEQTINPIQIIRYWNHSHTAPQDDLMLIRLAKPAILNEKVQPIALATSTVKPGTICMLSGLDWSQNNNGRHPDLRQNLEAPVMSDTACQETEQGKSHRNSICVKFLKVFSRIFGELAVATVICKNKLQGIEVGHFMGGDVGIYTNVQKYVSWIESTTKDK
What is the function of this protein?
Plays a role in male fertility.  May have a role in sperm migration or binding to zona-intact eggs.  Involved in the activation of the proacrosin/acrosin system.
What are the official names of this protein?
Probable inactive serine protease 37, Probable inactive trypsin-X2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Secreted.
Protein: PROA_ERWT9
Sequence: MLEQMGQAAKAASYQLSVLSTAEKNQLLMTIADRLEAQSAEILAANQQDLADARQNGMSAALLDRLMLDRQRLKGIADDVRQVCRLADPVGVVIDGGKLDSGLRIERRRVPLGVVGVIYEARPNVTVDVASLCLKTGNAVILRGGKETYRTNAATVRVIQDALKRHGVPAAAVQAIESPDRELVNQLLKLDRYVDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDRSIEQEAALKVIVNAKKQRPSACNSVETLLIDAAIADSFLPALSARMAQEGISLHADARSLPLLQQGPACVSAVTDAQYRDEWLALDLNVKLVDDLSEGIAHIREYGTQHSDAILTRTIKHADRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWVAFGDDTVRD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HB21_MOUSE
Sequence: MVWLPRVPCVAAVILLLTVLSPPMALVRDSRPWFLEYCKSECHFYNGTQRVRLLERYFYNLEENLRFDSDVGEFHAVTELGRPDAENWNSQPEFLEQKRAEVDTVCRHNYEISDKFLVRRRVEPTVTVYPTKTQPLEHHNLLVCSVSDFYPGNIEVRWFRNGKEEKTGIVSTGLVRNGDWTFQTLVMLETVPQSGEVYTCQVEHPSLTDPVTVEWKAQSTSAQNKMLSGVGGFVLGLLFLGAGLFIYFRNQKGQSGLQPTGLLS
What are the official names of this protein?
H-2 class II histocompatibility antigen, E-B beta chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: COAD_HAHCH
Sequence: MNTVIYPGTFDPITNGHKDLIARASRIFDKVVVAVAASPKKNPLFSLEERVDLVRQVVKPFPNVDVKGFSNLLADFVQQNQANIILRGLRAVSDFEYEFQLADMNRKLAPNVESLFLTPANHLSYISSTLIREIAALGGDVTEFVDPIVSKALQQQFALRK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_THEFY
Sequence: MATHLKSHELFNRARSVIPGGVNSPVRAFKAVGGTPPFMVSGKGPYLTDADGNTYVDLICSWGPLILGHAHPAVVEALAKAAAQGTSYGAPTEAEVELAEEIVSRTPVEKVRLVNSGTEATMSAIRLARGATGRAKVVKFAGNYHGHVDALLAAAGSGVATFALPDSPGVTGASAADTIVLPYNDIAAVEAAFAEAGDEIACVIAEACPANMGVVPPRDGFNAKLREITARHGALLILDEVLTGFRVSPSGWYGLEGVAPDLMTFGKVMGGGLPAAAFGGRADLMDQLSPEGSVYQAGTLSGNPLATAAGLATLRNATPEVYAHIDAAAARVSAAVSEALTAEGVPHRIQHGGNLFTVFFTDTEVVDFDGARAQNTARYAAFFQAMLEQGVYLPPAAFEAWFFSAAHDDAALDRVVSALPAAAKAAAQVA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_SALTI
Sequence: MSSYENHQALDGLTLGKSTDYRDNYDASLLQGVPRSLNRDPLGLTADNLPFHGADIWTLYELSWLNSQGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQTRFDTWETVRQTLERDLRACAQGNVSVRLHRLDELEGQPVAHFHGTCIDDQDISIDNYQFTTDYLQHAVSGEKQVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRKIDREKLLRYLVSFRHHNEFHEQCVERIFNDILRFCQPETLSVYARYTRRGGLDINPWRSNTDFVPATGRLARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_FLAPJ
Sequence: MLSSFFLTQHLEAGTDEAGRGCLAGPVTAAAVILPENFESKILNDSKQLSEKTREQLKPIIEALAISFSVTHLDPLIIDEINILNASLKAMQECVLQLNPTPLYIIADGNRPLLSKNSFKKCSGKIFTNREIEILQSIPSSSIIKGDSKYLSIAAASVLAKTYRDEYMNTIHEEFPMYNWKKNKGYPTKEHREAIRKYGVTKYHRMTFRLLPEQTVLDL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAL_BACSU
Sequence: MRIMASHDTPVSPAGILIDLDGTVFRGNELIEGAREAIKTLRRMGKKIVFLSNRGNISRAMCRKKLLGAGIETDVNDIVLSSSVTAAFLKKHYRFSKVWVLGEQGLVDELRLAGVQNASEPKEADWLVISLHETLTYDDLNQAFQAAAGGARIIATNKDRSFPNEDGNAIDVAGMIGAIETSAQAKTELVVGKPSWLMAEAACTAMGLSAHECMIIGDSIESDIAMGKLYGMKSALVLTGSAKQGEQRLYTPDYVLDSIKDVTKLAEEGILI
What is the function of this protein?
Catalyzes the dephosphorylation of C5 and C6 carbon sugars in vitro (PubMed:21575135, PubMed:25848029).  Catalyzes the dephosphorylation of 3'-AMP and phosphoserine in vitro (PubMed:25848029).
What are the official names of this protein?
Sugar-phosphatase AraL, Arabinose operon protein AraL, Phosphoserine phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: RS18_LEGPA
Sequence: MSAYFRRKKMCRFSAEGGNEIDYKDINLLKNYITETGKIVPSRITGTQTRFQRQLAKAIKHARFIGLLPYCDSHR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: CBID_GEOSW
Sequence: METKKTLREGYTTGACATAATKAALTALITGIIQTEATIYLPVGRWATFAIEACEIYGESVKATVIKDGGDDPDATHGAAIVSTVSWAEQPGIHLDGGKGVGRVTKPGLPVPVGEAAINPIPRKMIHETAREVLEQYGISRGVNVIISVPNGEEIAKKTLNARLGIIGGISILGTRGIVIPFSTSAYRASIIQAIQVAKANGCDHVVITTGGRSEKFAMRQYPHLPEEAFIEMGDFVGFTLKQCKRLGIRTVSMVGMMGKFSKVAQGIMMVHSKSAPIDFSFLAAIAEQAGASPELVAAVREANTASQVGEMMQEAGNERFFEILCDHCCLSALREVGGGMTVETSLYTMGGQLLGKAVRNDAGD
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: Y846_CAMJE
Sequence: MIFLIFSFIVLLIFGLANVYIYKRLIKKITLFKYFYKIFSFIFIVLFLAQAVFLIFRRDEYLSDTWYEILAMFYAPTYCLFFMTLAWDFVKLILALMGKRDKTYNLILRLIFELSLIVLSVFLIYASINNALKTPEVKSVDVEIPNLKKDLKIVMLTDIHLGKNLHENFLDKLITKVNLQSPDMVVIVGDLIDTNPKDLKNYISKLNDFNSTYGTFYALGNHEYYHGINEVLDLLRKHTNMKILVNQNLDLGFIDIAGLGDLAGLDRGLYAPDLARIKVDLNTSKASILLTHQPKTALLYDLSDFDLVLSGHTHGGQIFPFMFLVKLQQGFVHGLYDLGEKTKLYVSSGAGFWGPSLRVFAPSEIVILNLKGKK
What are the official names of this protein?
Uncharacterized metallophosphoesterase Cj0846.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily.
Protein: NNAAH_MYCGE
Sequence: MKQKIIIFGGSFDPIHNAHLYIAKHAIKKIKAQKLFFVPTYNGIFKNNFHASNKDRIAMLKLAIKSVNNALVSNFDIKTKNAFSINTVNHFKSCYPTSEIYFLIGSDKLNELEKWDHIQQLKDLCTFVCYERKPYPFNKKIANQFNVKYLAKCPLEIASSKLLNQPRKKLIPLAVLNYINTNHLYLIPTLKAMVDDKRFQHCLRVGKLAKQLAIANKLDAKRAFVAGAYHDLAKQLPVDQLVNIATSELKITNYPSWKVLHSYVGAYILKNWFGVKDKMIINAIKNHTIPPKQVSKLDMIVYLADKLEPNRKQEQWSGGIEIDQLVKLAKSNLKQAYLITLKYVQNLVKD
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield ADP.
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase/Ap4A hydrolase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the Ap4A hydrolase YqeK family.
Protein: NIT_ARMGA
Sequence: MPISLNPSHSNTQTFKVAAVQAEPVWLDLQGGVEKTIRIINEAAAEGAKIIGFPEVFIPGYPWTPWANNFVDAQVVLKKYQANSMPLHSPEMDRIREAVKEADVNIVLGFSERDGSSLYIAQVTITSDGKIANHRRKIKPTHYEKTIFGDGSAQSIYNVVQTPYGRLGSLNCWEHIQPWLKTHFYSQYPQIFVGGWWPAFPPHTGGSPYIVSGEASSRMSQLVSMEGGLFGIVCCHVVSEAGARKMRMLGFPWFTFPGGGFSVIYGPDGAALTDPVDPGKEVVLYANISLDKIDDVKLVADIMGNYSRFDLFHTTVVNGKNWKPVAYGDPDEQAASKAQQAEIDNAGKGSIVPSKL
What is the function of this protein?
Catalyzes the hydration of cyanide to formamide.  Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.
What are the official names of this protein?
Cyanide hydratase, CHT, Cyanide-degrading nitrilase, Formamide hydrolyase, NitAg.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: METXA_MYCS2
Sequence: MTIIEERATDTGMATVPLPAEGEIGLVHIGALTLENGTVLPDVTIAVQRWGELAPDRGNVVMVLHALTGDSHVTGPAGDGHPTAGWWDGVAGPGAPIDTDHWCAIATNVLGGCRGSTGPGSLAPDGKPWGSRFPQITIRDQVAADRAALAALGITEVAAVVGGSMGGARALEWLVTHPDDVRAGLVLAVGARATADQIGTQSTQVAAIKADPDWQGGDYHGTGRAPTEGMEIARRFAHLTYRGEEELDDRFANTPQDDEDPLTGGRYAVQSYLEYQGGKLARRFDPGTYVVLSDALSSHDVGRGRGGVEAALRSCPVPVVVGGITSDRLYPIRLQQELAELLPGCQGLDVVDSIYGHDGFLVETELVGKLIRRTLELAQR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_RHOBA
Sequence: MSAIQPPKPVERKIELEPHQILLKPLVTEKGVHRATRNNQYAFQIHRDATKLDVKKAVEHLFDVKVLKVRTQTRKGKARRFKYKIGRTSDWKKAIVSLHEDHRIDFF
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: SYI_BURO1
Sequence: MSNKKADSKPQAKYPVNLLDTPFPMRGDLPKREPQWVKEWEARGIYEKIRAASQGRPKFILHDGPPYANGDIHLGHAVNKILKDIVVKSRNMAGFDAPYVPGWDCHGMPIEIQIEKQFGKSLPAAEVMSKARAYATEQIEKQKVGFKRLGVLGDWANPYKTMNFVNEAEEIRALGKIIEKGYVYRGLKPVNWCFDCGSALAEAEVEYKDRTDPTIDVMFAFAEPEKTAHAFGLPALPRAEGGIVIWTTTPWTIPANQALNLHPEIIYALVDTERGLLIIAEERVEACMTDFKLTGRVVATAPGVKLANLRFHHPLASAHPGYKRTAPVYLGDYVTTDTGTGVVHSSPAYGIEDFMSCKAHGMTDSDFINPVMGDGRYIESLPLFGGLSIWDANPKIVDALNAAGSLLRSEKYTHSYMHCWRHKTPIIYRATSQWFAGMDVTPQDGGKTLRETALEGVDATAFYPSWGKQRLFSMIANRPDWTLSRQRQWGVPMAFFVHKETGELHPRTLELLEEVAKRVEQSGIEAWQSLDPRELIGDDANLYEKNRDTLDVWFDSGTTHWHVLRGSHKDQLQFPADLYLEGSDQHRGWFHSSLLTASMIDGRAPYKGLLTHGFTVDGEGRKMSKSLGNGIDPHEVANRLGAEIIRLWIASTDYSGELAISEEILKRVTEGYRRIRNTLRFLLANLSDFDFAQHAVPVDEWLEIDRYAVAFSQQLQTELLGHYEKYEFHPVVAKLQTYCSEDLGGFYLDVLKDRLYTSAADSRARRSAQTALYHLTHGLLRVLAPFLSFTAEEAWKVFQPASDTIFTETYYAYPEVAGSAALIEKWALLRDVRGSVTKALEEARTANRIGSSLQAEVAVHASGARYDALTSLGDDLKFVLITSAATVVKVDDEAQESVDVAASKYQKCERCWHYREDVGAHAEHPTLCGRCFSNLFENGEIRSAA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
Protein: DXS_XANC5
Sequence: MIDTTRYPRLSRIQTPDDLRRFDEAELTAIAEELRSYLIESVGKSGGHFAAGLGVIELTVALHYLYQTPVDQLVWDVGHQTYPHKILTGRRDQIHTVKQKDGVAPFPKREESIYDTFGVGHSSTSISAALGMAIAAQRNGDDRKVVAVIGDGAMTAGMVYEALNHAGGMDPEPNLLVILNDNRMSISEAVGGLTKMLGRASGSRTLNAIREGGKKILGDKKNNPTARFVRRWEEHWKGMFVPSTLFEEMGFHYTGPIDGHDLPSLVGALKTLQTLKGPQLLHVITTKGKGYELAEGDQIGYHAVGPFDPSKGLVAKAGAKKPTYTDVFSDWVCDMAAAEPKLLVITPAMREGSGLVRFSKEYPQRYFDVAIAEQHAVTLAAGMATQGAKPVVAIYSTFLQRGYDQLVHDVAVQQLDVLFAIDRGGVVGPDGATHAGNLDLSFLRCVPHMVVMAPADEAECRQMLSTGVQYQGPAAVRYPRGTGPGVALDASLATLPIGKAQLRHSGTRIALLGFGATVDAAEAVGRELGLTVVNMRFVKPLDKAMLLELAKTHDGFVTIEDNVVAGGAGAGVSELLNAEAITMPMLHLGLPDSFQHHASREDLLAEAGIDQAGIRAAVLKRWPQLMTSKTPALNAAAG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: OLFL1_RAT
Sequence: MMVALPGASASLVLFLAAFLPPLQHAQDPAMVHYIYQRFQVLEQGLEKCAQTTRAYIQDFQEFSKNLSTMLGRCQTHTNEYRSAVDNLALRVERAQREIDYLQYLRESDFCVESEEKTSAEKVLQEAEEEKKIRTLLNTSCDNMLMAIKSLKIVKKTVDPEGSWMKDAGSTSAKVYLLAGSRNNTVWEFANLRAFMEDSVKPGPRKLTLPLSWQGSGQVVYQSFLFFHNQGTSNEIIKYNLQKKTVEDRMLLPGGAGRAPIYQHSLSTYIDLAVDEHGLWAIHSGPGIQGHLVLTKIEAGTLGIEHSWDTPCRSQDAEASFLLCGVLYVVYSSGGQGPHRITCVYDPLGTVREEHLPNLFFPRRARSHSMIHYNPRDKQLYAWNEGYQIIYKLQTKKKLPLE
What are the official names of this protein?
Olfactomedin-like protein 1.
What are the subcellular locations of this protein?
Secreted.
Protein: IF2_LISMC
Sequence: MSKVRVYEYAKEHQVSSKKVIEALKDLGIEVANHMSTINENALRQLDNAIDGTNKKAEAPKKETTSNENGNSKGPNKPNMTNSNEKSNKPNNPAGQANKPATANKSQGAKPATNKPANTSKQTQSSGNQQQAGGQKRNNNNNSNRPGGGNPNRPGGNNRPNRGGNFNNKGRNTKKKGKLNHSTVPPTPPKPKELPEKIVFSESLTVAELAKKLYREPSELIKKLFMLGVVATINQSLDKDAIELICDDYGVQVEEEIKVDVTDLDVYFENELNEAVDESKLVERPPVVTIMGHVDHGKTTLLDSLRNTKVTLGEAGGITQHIGAYQLEIHDKKITFLDTPGHAAFTAMRARGAQITDITILVVAADDGVMPQTIEAINHAKAAGMPIIVAVNKIDKPQANPDRVMQELTEYELVPEAWGGDTIFAPISAKFGEGLENLLDMILLVSEVEELKANPDRRAIGSVIEAELDKGRGPVATLLVQDGTLNIGDPIVVGNTFGRVRAMVNDLGRRVKKVGPSTPVEITGLNDVPQAGDRFVVFEDEKTARNIGETRASRALVAQRSATNRVSLDNLFEHMKAGEMKEVNVIIKADVQGSVEALAASLRKIDVEGVNVKIIHTAVGAINESDITLAAASNAIVIGFNVRPTAQAREAAENESVDIRLHRVIYKAIDEIEAAMKGMLDPEFQEKIIGQAQVRQTINVSKVGTIAGCYVTDGKITRDSGVRIIRDGIVVFEGEIATLKRFKDDAKEVAKGYECGITVQNFNDIKEDDVIEAYVMEEIERK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMC_HAMD5
Sequence: MSDLTPPSQILLRHTREFAERSVIFSGDLQDLLPAQFNAKQIRVHTQEYHHWRLLSPVLKNDIQFGVLPSEDLVSKTDTVIFYWPKNKAQAQFQLEHLCSLFPSQTNIFIVGENRSGIGSAKDLLAENVGLHKMDAARRCSLYYGCLKQKPVFNMESQWRRYQVKDVQIKTLPGVFSANQLDEGSQLLLSSFDIPLSGKVLDLACGAGVLGTILARQSPQIELTLSDVNAAALESSRANLAVNHIKARVVPSDLYSDIPERFNLILSNLPFHKGLKTDIKMIEKCIEEAPGHLYKGGKLRLVANAFLPYPKLLNRTFGHYEVLTQNARFKVYQATL
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_CLOBA
Sequence: MPTVGLFNQEGKQVGDIQLNANVFEVEVNKHALHQVVVALLANKRQGTQSAKTRTEVRGGGIKPWRQKGTGRARQGSIRAPQWIKGGIVFAPKPRDYRVSIPKSMRRVAMKSALTSKVNDGQMVVLESLSFEAPKTKQFIEMLSAFNAKKTLIITAESNEAVYKSARNIQGVSVIPVNNINVYDLLKFEKLIITKDAVSKIEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RB39B_HUMAN
Sequence: MEAIWLYQFRLIVIGDSTVGKSCLIRRFTEGRFAQVSDPTVGVDFFSRLVEIEPGKRIKLQIWDTAGQERFRSITRAYYRNSVGGLLLFDITNRRSFQNVHEWLEETKVHVQPYQIVFVLVGHKCDLDTQRQVTRHEAEKLAAAYGMKYIETSARDAINVEKAFTDLTRDIYELVKRGEITIQEGWEGVKSGFVPNVVHSSEEVVKSERRCLC
What is the function of this protein?
Small GTPases Rab involved in autophagy (PubMed:27103069).  The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:27103069).  May regulate the homeostasis of SNCA/alpha-synuclein.  Together with PICK1 proposed to ensure selectively GRIA2 exit from the endoplasmic reticulum to the Golgi and to regulate AMPAR compostion at the post-synapses and thus synaptic transmission (By similarity).
What are the official names of this protein?
Ras-related protein Rab-39B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Note=Partial colocalization with markers that cycle from the cell surface to the trans-Golgi network.