PharMolix/UniProtQA huggingface dataset:
Protein: GPH_NEIMA
Sequence: MNAAIEHVQAVAFDLDGTLCDSVPDLAAAAEAMLEQLGMKPLPAKVVESYVGDGIGKLVHRVLTNDRDREADSELWEKGFVSYMKYYRDHLSVFTRPYPETEAGLALLKSLGIPLAVITNKNEILAAELLKQLGLADYFSLILGGDSLPEKKPSPLPLRHAAEVLGIDVANMVMVGDSRNDIIAAKAAGCLSVGVTFGYGDMTLLSQDDATRPDWIIGSLPEIYENLQPQKNKEE
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: IL1R2_RAT
Sequence: MFILLVLVTGVSAFTTPAVVHTGRVSESPVTSEKHPVLGDDCWFRGRDFKSELRLEGEPVVLRCPLVPHSDTSSSSRSLLTWSKSDSSQLIPGDEPRMWVKDDTLWVLPAVQQDSGTYICTFRNASHCEQMSLELKVFKNTEASFPLVSYLQISALSSTGLLVCPDLKEFISSRTDGKIQWYKGSILLDKGNKKFLSAGDPTRLLISNTSMGDAGYYRCVMTFTYEGKEYNITRNIELRVKGITTEPIPVIISPLETIPASLGSRLIVPCKVFLGTGTSSNTIVWWMANSTFISVAYPRGRVTEGLHHQYSENDENYVEVSLIFDPVTKEDLNTDFKCVATNPRSFQSLHTTVKEVSSTFSWGIALAPLSLIILVVGAIWIRRRCKRQAGKTYGLTKLPTDNQDFPSSPNQIKEMK
What is the function of this protein?
Non-signaling receptor for IL1A, IL1B and IL1RN.  Reduces IL1B activities.  Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1.  Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B.  IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.  The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors (By similarity).
What are the official names of this protein?
Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell membrane. Secreted.
Protein: ATPB_STRP6
Sequence: MSSGKIAQVVGPVVDVMFASGDKLPEINNALIVYKDSDKKQKIVLEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDLEEPFAEDVDRQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTQKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKYDHLPEDAFRSVGPIEDVIKKAEKMGF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BUD2_YEAST
Sequence: MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLNDWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANCNFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNKNFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLRETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPIEVKPEIGELEFEKITENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPKAEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKSSNKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS
What is the function of this protein?
Stimulates the GTPase activity of BUD1/RSR1.  Participates in the regulation of bud-site selection.
What are the official names of this protein?
Inhibitory regulator protein BUD2/CLA2, Bud site selection protein 2.
Protein: MEND_ECO81
Sequence: MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGISWQQRLGDWWQDDKPWLREAPRRESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETTLVDAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: YF22_SCHPO
Sequence: MSSAVTPSDQGLLPRGPIALEEFVKPFCDRFGLTKLPRHMHVILLSALFYQIINILSPVISRHLSTHYAKLSKKTRLNWDAHVVSSVQSIVLICLGYTCLKEVNAFPDKLFGYSVVAGDIYALTAGYFVWDLYITVRYVHITGIGFVIHAIAALFVITFSYRPYLMYYGPTYLSWELSTPFLNIHYFLDKTNRTGSKFQMINGFILIVTFICVRIAWGWFSAYSTAIEILNHINVAPWALSLFYLAANMSLNCLNLFWVSKMIDAIRRRAHGEKKSTPLQVTSEYAKKNI
What are the official names of this protein?
Uncharacterized TLC domain-containing protein C17A2.02c.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AFP1_PASAL
Sequence: PGAGSQEERMQGQMEGQDFSHEERFLSMVRE
What is the function of this protein?
Has antifungal activity against C. gloeosporioides but not against B. cinerea and Fusarium sp.  or against various yeasts.  Has no antibacterial activity.
What are the official names of this protein?
Antifungal protein 1, Pa-AFP1.
What is the protein family that this protein belongs to?
Belongs to the 2S seed storage albumins family.
Protein: COX2_NIVCU
Sequence: MAYTFQLGLQDATSPIMEELTNFHDHTLMIVFLISSLVLYVISLMLTTKLTHTNTMDAQEVETIWTILPAVILILIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKHFENWSASMI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RNH2_CLOP1
Sequence: MDNLIKDMRENLNSYSFKVVSDLVKELDVNRDNKAQIKELADLLKEDKRKNVSSLGNRLEKNLNNLIKEEERVKNMYLFDKSFGDYKYVAGVDEVGRGPLAGPIVSAAVILDSSDLDDIILYINDSKKLSEHKREELSEIIKEKALSYSISMCDSKEIDEKGIGYCNNHVFIKACEGLSIKPDLVLSDGYLIKNFNGENKHVIKGDTKSACIACASIIAKVYRDNIMKEYHKKYPQYDFEKNVGYGTKTHVDALKEVGPTEIHRMSFLKNIL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTC9C_MACFA
Sequence: MEKRLQEAQLYKEEGNQRYREGKYRDAVSRYHRALLQLRGLDPSLPSPLPNLGPQGPALTPEQENILHTTQTDCYNNLAACLLQMEPVNYERVREYSQKVLERQPDNAKALYRAGVAFFHLQDYDQARHYLLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQLYLGMFG
What are the official names of this protein?
Tetratricopeptide repeat protein 9C, TPR repeat protein 9C.
What is the protein family that this protein belongs to?
Belongs to the TTC9 family.
Protein: SYFA_SALDC
Sequence: MSHLAELVANAAAAINQASDVAALDNVRVEYLGKKGHLTLQMTTLRDLPPEERPAAGAVINAAKEQVQQALNARKAELESAALNARLAAETIDISLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWFDATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_NOVAD
Sequence: MLQPKKTKFRKAFKGRIHGLAKGGTDLNFGSYGLKALEPERVTARQIEAARRAITRHIRRQGRLWIRVFPDVPVSKKPAEVRQGKGKGSIEYWAARVKPGRILFELDGVPGPLAAEAFSRAAMKLPIKTKVVARLGDTSHLAGE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RS24_METM6
Sequence: MDISIISDKNNPLLYRREIKFTVSFDAATPSIKDVKMKLVAVLNADKKVLVVDTLDQIFGKLEAEGYAKIYNDEKAMATIETKSVLEKNKIEEEAAEAEVAEE
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: UVRA_PASMU
Sequence: MDKIEVRGARTHNLKNINLTIPRDKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTVTEIHDYLRLLFARVGEPRCPNHDVPLAAQTISQMVDKVLSLPEESKMMLLAPVVKERKGEHVKLLEQIAAQGYIRARIDGEICDLSDAPKLELHKKHTIEVVVDRFKVRSDLATRLAESFETALELSGGTAVVASMDEPETEELVFSANFACPHCGYSVPELEPRLFSFNNPAGACPTCDGLGVQQYFDEKRVVQNPSISLASGAVKGWDRRNFYYYQMLTSLAKHYEFDIESPFEALPKKIQQIILNGSGKEEIEFQYMNDRGDVVVRHHAFEGILNNMARRYKETESLSVREELAKNISTCPCHDCGGSRLRQEARHVYIGTTTLPDVAEKSIGETLHFFSELHLSGQRAQIAEKILKEIKERLQFLVNVGLDYLSLSRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLNTLLHLRNLGNTVIVVEHDEDAIMAADHIIDIGPGAGVHGGQIVAEGSAKAIMANPHSITGKFLSGVEKIEIPAKRTALDKKKMLKLEGATGNNLKSVNLAIPVGLFTCVTGVSGSGKSTLINDTLFPLAQNALNRAENTQFAPYQSISGLEFFDKVIDIDQSPIGRTPRSNPATYTGLFTPIRELFAGVPESRARGYNPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDVYVPCEQCKGKRYNRETLEIRYKGKTIHQVLEMTVEEAREFFDAIPQIARKLQTLMDVGLSYIRLGQSSTTLSGGEAQRVKLATELSKRDTGKTLYVLDEPTTGLHFADIKQLLTVLHRLRDQGNTIVVIEHNLDVIKTADWIIDLGPEGGNGGGQIIATGTPEQVAEVKGSHTARFLKTLLQKR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 16D10_MELAR
Sequence: MFTNSIKNLIIYLMPLMVTLMLLSVSFVDAGKKPSGPNPGGNN
What is the function of this protein?
Plays a role in the differentiation or division of feeding cells (syncytia) induced in plant roots during infection.  Promotes host root growth.
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 16D10.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host extracellular space. Note=Secreted into host root cells via the nematode stylet to transform the recipient cells into enlarged multinucleate feeding cells called giant-cells or syncytia.
Protein: Y2409_STAAS
Sequence: MSNMNQTIMDAFHFRHATKQFDPQKKVSKEDFETILESGRLSPSSLGLEPWKFVVIQDQALRDELKAHSWGAAKQLDTASHFVLIFARKNVTSRSPYVQHMLRDIKKYEAQTIPAVEQKFDAFQADFHISDNDQALYDWSSKQTYIALGNMMTTAALLGIDSCPMEGFSLDTVTDILANKGILDTEQFGLSVMVAFGYRQQDPPKNKTRQAYEDVIEWVGPKE
What are the official names of this protein?
Putative NAD(P)H nitroreductase SAS2409.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
Protein: MSI1H_CAEEL
Sequence: MTTTVSTGATAVATLRETSPPVDGHEEARLNADSDDGSHGSQDPGKMFIGGLSWQTTAENLRDYFGRFGEVNECMVMRDPATKRARGFGFITFVDPSSVDKVLNNREHELDGKKIDPKVAFPKRTQAKLVTKTKKVFIGGLSATSTLEDMKQYFETYGKVEDAMLMFDKATQRHRGFGFVTFDSDEVADKVCEIHFHEINGKMVECKKAQPKEVMLPVQLNKSRAAAARNLYGMPPETLLAYAQYLPRFGGNLMYPNFTNVFNNMPGGYSGLSTPGGSSNRPPHQFDTASLYSLNNGGQLLDSQAQMFMNQQSYHSHSKY
What is the function of this protein?
RNA binding protein that regulates the expression of target mRNAs at the translation level (PubMed:24630719).  Binds RNA containing the 5'-[GA]U(1-3)AGU-3' motif located in the 3' UTR of the target mRNA (By similarity).  Binds to the mRNA of three Arp2/3 complex components arx-1, arx-2 and arx-3 and negatively regulates their translation during association learning (PubMed:24630719).  Plays a role in time-dependent memory loss and the retention of conditioned behavior over time, probably through negative regulation of the Arp2/3 actin cytoskeleton branching complex and regulation of synapse size (PubMed:24630719, PubMed:36223338).  Required for two aspects of male mating behavior: turning around the hermaphrodite head or tail and vulva location (PubMed:11122376).
What are the official names of this protein?
RNA-binding protein Musashi homolog 1, Musashi-1.
What is the protein family that this protein belongs to?
Belongs to the Musashi family.
Protein: EIF3I_NEMVE
Sequence: MKPLALHGHERNITQIKYNRMGDLLFSAAKDTRPTVWYSLNGERLGTYNGHGGAVWCIDVNYDTTQFISGGADNCLRLWDCEKGVTLSKIETKSAVRTCGFSYGGNEIMLSTDRQMGQSCRILIFDVRDNMESPILTIPVDNSKVTAGLWGPLDQFLVTGHENGELCQWDVKSGNKLISVQEHSKQINDIQMYKDSTMFVTASKDTTAKLFDTDSLRHLKTYKTDRPVNSAALSPIKDHVVVGGGQEAMEVTTTSTRVGKFDARFFHVVFEEEIGRVKGHFGPINSLAFHPDGRSYSSGGEDGYVRIHSFDPSYDDIEFEY
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAI_BACSU
Sequence: MEPIGRSLQGVTGRPDFQKRLEQMKEKVMKDQDVQAFLKENEEVIDQKMIEKSLNKLYEYIEQSKNCSYCSEDENCNNLLEGYHPKLVVNGRSIDIEYYECPVKRKLDQQKKQQSLMKSMYIQQDLLGATFQQVDISDPSRLAMFQHVTDFLKSYNETGKGKGLYLYGKFGVGKTFMLAAIANELAEKEYSSMIVYVPEFVRELKNSLQDQTLEEKLNMVKTTPVLMLDDIGAESMTSWVRDEVIGTVLQHRMSQQLPTFFSSNFSPDELKHHFTYSQRGEKEEVKAARLMERILYLAAPIRLDGENRRHP
What is the function of this protein?
Probably involved in DNA replication.
What are the official names of this protein?
Primosomal protein DnaI.
Protein: SEMA_VAR67
Sequence: MIYLYTADNVIPKDGLQGAFVDKDGTYDKVYILFTVTIGSKRIVKIPYIAQMCLNDECGPSSLSSHRWSTLLKVELECDIDGRSYSQINHSKTIKQIMIRYYMYSLIVLFQVRIMYLFYEYH
What are the official names of this protein?
Semaphorin-like protein A43.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
Protein: PACC1_HUMAN
Sequence: MIRQERSTSYQELSEELVQVVENSELADEQDKETVRVQGPGILPGLDSESASSSIRFSKACLKNVFSVLLIFIYLLLMAVAVFLVYRTITDFREKLKHPVMSVSYKEVDRYDAPGIALYPGQAQLLSCKHHYEVIPPLTSPGQPGDMNCTTQRINYTDPFSNQTVKSALIVQGPREVKKRELVFLQFRLNKSSEDFSAIDYLLFSSFQEFLQSPNRVGFMQACESAYSSWKFSGGFRTWVKMSLVKTKEEDGREAVEFRQETSVVNYIDQRPAAKKSAQLFFVVFEWKDPFIQKVQDIVTANPWNTIALLCGAFLALFKAAEFAKLSIKWMIKIRKRYLKRRGQATSHIS
What is the function of this protein?
Proton-activated chloride channel that mediates import of chloride ion in response to extracellular acidic pH (PubMed:31023925, PubMed:31318332).  Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling (PubMed:31023925, PubMed:31318332).
What are the official names of this protein?
Proton-activated chloride channel, PAC, hPAC, Acid-sensitive outwardly-rectifying anion channel, ASOR, Proton-activated outwardly rectifying anion channel, PAORAC, Transmembrane protein 206, hTMEM206.
What is the protein family that this protein belongs to?
Belongs to the proton-activated chloride channel family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KVX01_RAT
Sequence: DVQMTQSPSYLAASPGESVSISCKASNKSISNNLAWYZZKPGKANKLLISSGSTLQSGTPSRFSGSGSDTDFTLTIRSLEFQDFAVYYCZZYNEPYYTFGAGTMLELKR
What are the official names of this protein?
Ig kappa chain V region S211.
Protein: YR784_MIMIV
Sequence: MINWLHLPDEIWLLIGNFISDREICCLAFVNTRFLNLLSYNKINQNLVLECAIEVDNIYIINKLIDKTDVNGLKFVMRWSALHGSFQIIKSIIRKDHNNDLLDLHAINWSIESNHLHISKYLIDKYNIVIIPESAFIYGRLDIIDWMFSRQNQNNANKKSTIKKTVDFLKSKFISHDYFYDSMIELACLYGHVHVVQYFIDNQCSVRQKWLYYSCLSGNFDLVKLLCKNGCRIFSNRRLINTAITGGNLDIVRYCLLHSKIDLAQNNFAMKIAIKTGHIGIVRLLVSHGSDIHFDNGECMIIASRGGFANIVKFFLENKVYMSEKVLKIAAIRGYLDIIKVFIKYASACMSNINSVCKSNGSMVVDNHINYIVNITRNFNMRKILIWSLINNRINIVTYLLEIFPKLREILNQIMYQHPEISEKIDLDSLYKN
What are the official names of this protein?
Putative ankyrin repeat protein R784.
Protein: RS14_PSESM
Sequence: MAKKSMKNRELKRQLTVAKYAKKRAELKAIIVDLNASPEARWEATVALQKQPRDASAARMRNRCRITGRPHGVYRKFGLGRNKLREAAMRGDVPGLVKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PSTA_METJA
Sequence: MSPIKHKTIRMIKDKIFLFIVGALTLLAILPLFHIIISIVEKGLPIIMERGLTFITGTLSEGGIGPAIVGTLMLTFLATLIGLPLAFLAGAYAYEFPNSFIGRATKMLLQIMLEFPTILVGTFVMGMLVVPMGTFSALAGALALALILTPYVAVYTEEAMAEVPKIYKEGGYALGCTRAQVIFKVITKMAKKGILTGILIGMAKVAGETAPLLFTAGGLYEVYPTNPLEPVGAIPLLIYTLVQSPSIEDHQMAWGAALVMLIIFLAIFVPIRYALKDDIKL
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable phosphate transport system permease protein PstA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RN114_PIG
Sequence: MAAQPQDREGGAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSTLAPGVRAVELERQIESTETSCHGCRKNFFLSKIRAHVATCSKYQNYIMEGVKATTKDASLQPRNVPNRYTFPCPYCPEKNFDQEGLVEHCKLVHSTDTKSVVCPICASMPWGDPNYRSANFIEHIQRRHQFSYDTFVDYDVDEEDMMNQVLQRSLLDQ
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates.  In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity.  Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3.  May promote the ubiquitination of TRAF6 as well.  Acts also as a negative regulator of T-cell activation.  Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation.  Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C.  This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence.  May play a role in spermatogenesis (By similarity).  Inhibits classical swine fever virus replication by mediating 'K27'-linked ubiquitination of viral NS4B and inducing its degradation via the proteasome (PubMed:31413123).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF114, RING finger protein 114, RING-type E3 ubiquitin transferase RNF114, Zinc finger protein 313.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PYRF_LATSS
Sequence: MTNPVIIALDFPNWQKTDQFLQQFPKDEALFVKIGMELFYQEGPQLIKTLKARDYRIFLDLKLYDIPNTVQSAMTVIGQLGVDYTTIHAAGGQTMLQAGAAGLKAGAKQANVKPAKLLAITQLTSTNEAQMQQEQLVSVSLPESVAHYAQLAQQSDCDGVICSAQEITTIKSKTATDFLCVTPGIRPATSQNNDQKRAVTPLEAAQMHSNGIVVGRPITQASDPYQAYQAIKSEWESFK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: LOXA_PSEAE
Sequence: MKRRSVLLSGVALSGTALANDSIFFSPLKYLGAEQQRSIDASRSLLDNLIPPSLPQYDNLAGKLARRAVLTSKKLVYVWTENFGNVKGVPMARSVPLGELPNVDWLLKTAGVIVELIVNFVASLPASAAAQFERIATGLSGDLEAARQVHEALLEEAKNDPAAAGSLLLRFTELQTRVIAILTRVGLLVDDILKSASNLVTQRGQGDGLNRFRAVFGTLRLPEVADSFRDDEAFAYWRVAGPNPLLIRRVDALPANFPLGEEQFRRVMGADDSLLEAAASRRLYLLDYAELGKLAPSGAVDKLLTGTGFAYAPIALFALGKDRARLLPVAIQCGQDPATHPMFVRPAESESDLYWGWQMAKTVVQVAEENYHEMFVHLAQTHLVSEAFCLATQRTLAPSHPLHVLLAPHFEGTLFINEGAARILLPSAGFIDVMFAAPIQDTQATAGGNRLGFDFYRGMLPESLKARNVDDPLALPDYPYRDDGLLVWNAIRQWAADYVAVYYASDGDVTADVELAAWVGEVIGSGKVAGFRPITGRSQLVEVLTMVIFTASAQHAAVNFPQPSMMTYAPAICAMSAAPAPDSPSGKSEADWLKMMPPTLVALEKVNIYHLLGSVYHGRLGDYRQTGFPYAPVFSDRRVTASGGPLERFQARLKEVEATIRTRNQARRRPYEYLLPSRIPASTNI
What is the function of this protein?
Exhibits lipoxin synthase activity as part of a bacterial evasion strategy to suppress the host immune defense (PubMed:31474948).  Oxygenates polyenoic fatty acids including eicosatrienoate and docosahexaenoate to the corresponding (n-6)S-hydroperoxy derivatives (PubMed:14766977, PubMed:27500637).  In turn, this production of bioactive lipid mediators promotes bacterial persistence in host lung tissues by inhibiting the expression of major chemokines and recruitment of leukocytes (PubMed:31474948).
What are the official names of this protein?
Lipoxygenase LoxA, Arachidonate 15-lipoxygenase, 15-LOX.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Periplasm. Secreted. Note=Periplasmic with some activity further secreted to the extracellular milieu.