PharMolix/UniProtQA huggingface dataset:
Protein: ALGL_PSEPG
Sequence: MTLLKRISSPALLALALFGGAAHAALVPPQGYYEGIEKLKTGDGNFRCEAAPKPYTGALQFRSKYEGSDKARATLNVASEKAFRKSTEDITTLEKGVSKMVGQYMRDGRPAQLDCTLAWLGTWARADALLSTDYNHTGKSMRKWALGSMSGSWLRLKFSHSQPLAAHQAEAEVIEKWFARLAEQTVRDWSDLPLEKINNHSYWAAWSVMATAVATDRRDLFDWAVKEYKVGANQVDDQGFLPNEIKRKQRALAYHNYALPPLAMIASFAQANGVDLRKENNFALQRLGEGVLAGARDPSQFKARTGEKQDMKDLKVDSKYAWLEPWCELYHCVGDTLQRKHGMQPFNSFRLGGDLTRVYDPNAESKK
What is the function of this protein?
Catalyzes the depolymerization of alginate by cleaving the beta-1,4 glycosidic bond between two adjacent sugar residues via a beta-elimination mechanism.  May serve to degrade mislocalized alginate that is trapped in the periplasmic space.
What are the official names of this protein?
Alginate lyase, Poly(beta-D-mannuronate) lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SBT49_ARATH
Sequence: MARRADSFCLISCVLVSFVISVSAVTDDSQDKQVYVVYMGSLPSSRLEYTPMSHHMSILQEVTGESSVEGRLVRSYKRSFNGFAARLTESERERVAEMEGVVSVFPDINYKLQTTASWDFLGLKEGKNTKRNLAIESDTIIGFIDSGIWPESESFSDKGFGPPPKKWKGVCSAGKNFTCNNKLIGARDYTNEGTRDIEGHGTHTASTAAGNAVKNTSFYGIGNGTARGGVPASRIAAYKACSEMGCTTESVLSAFDDAIADGVDLISISLGANLVRTYETDPIAIGAFHAMVKGILTVQSAGNGGPNPGSVMSVAPWILTVAASNTNRGFVTKVVLGNGKTFVGKSLNAFDLKGKNYPLYGGSTDGPLLRGKILVSEDKVSSEIVVANINENYHDYAYVSILPSSALSKDDFDSVISYVNSTKSPHGTVLKSEAIFNQAAPKVAGFSSRGPNTIAVDILKPDVTAPGVEILAAFSPLNSPAQDKRDNRHVKYSVLSGTSMSCPHVAGVAAYIKTFHPEWSPSMIQSAIMTTAWPMNATGTAVASTEFAYGAGHVDPIAAINPGLVYEIGKSDHIAFLCGLNYNATSLKLIAGEAVTCTGKTLPRNLNYPSMSAKLPKSESSFIVTFNRTVTNVGTPNSTYKSKIVLNHGSNLKVEVSPSVLSMKSVKEKQSFTVTVSGSNIDPKLPSSANLIWSDGTHNVRSPIVVYTYSVSD
What are the official names of this protein?
Subtilisin-like protease SBT4.9, Subtilase subfamily 4 member 9, AtSBT4.9.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MCU4_ARATH
Sequence: MALRRAITKRLIDCYRSDVTQQHSFFRQLSPYNMKIHRQYMTSPNGPNLTDRIVGIRIESVSPPRREETPVMGLSVSETKKLLRLYQMEKVKERLREIPKSSVSYWEFIQICCESCGNDEQGSQMAKSLDHSGCVVVLGDIVFLHPHQIAKSMEAMIKQTSVLPNDPRKEELVQLATTKKSIDIEARRIVQAELYCGLGFLAVQTIGFMRLTFWELSWDVMEPICFFVTTIHFILGYIFFLRTSTEPSFEGLFRQRFKTKQKKLMERHGFDFLRYNELNSLFTTFPCKFHYPV
What is the function of this protein?
Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria.  Constitutes a pore-forming and calcium-conducting subunit.  Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
What are the official names of this protein?
Calcium uniporter protein 4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the MCU (TC 1.A.77) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYT_STRGG
Sequence: MSDVRVIIQRDSEREEHVVTTGTTAGELFPGQRTVVAARIGGELKDLSYELRDGESVEPVEISSEDGLNILRHSTAHVMAQAVQELFPEAKLGIGPPVKDGFYYDFDVEKPFTPEDLKAIEKKMQEIQKRGQKFSRRVVSDEAAREELADEPYKLELIGIKGSASSDDGADVEVGGGELTIYDNLDPKTGDLCWKDLCRGPHLPTTRFIPAFKLMRNAAAYWRGSEKNPMLQRIYGTAWPTKDELKAHLEFLEEAAKRDHRKLGNELDLFSFPDEIGPGLAVFHPKGGVIRRAMEDYSRRRHEEEGYEFVYSPHATKGKLFEKSGHLDWYADGMYPPMQLDDGVDYYLKPMNCPMHNLIFDARGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRSRGFTQDDAHIYCTKEQMAEELDRTLTFVLNLLRDYGLTDFYLELSTKDPEKYVGSDETWEEATETLRQVAEKQGLPLVPDPGGAAFYGPKISVQCKDAIGRTWQMSTVQLDFNLPERFDLEYTGPDGSKQRPVMIHRALFGSIERFFAVLLEHYAGAFPVWLAPVQAVGIPIGDAHIPYLQEFAAKARKQGLRVDVDASSDRMQKKIRNQQKNKVPFMIIAGDEDMANGAVSFRYRDGSQENGIPVDEAIAKIAKAVEDRVQV
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_PHOV8
Sequence: MAAKPGIPKGTRDFSPVEMAKRNYIFNTIRDVFHLFGYQQIETPSMENLSTLMGKYGDEGDKLLFKIQNSGDYFNGITDEELLSRNAVKLASKFCEKGLRYDLTVPFARYVVMHRDEISFPFKRYQIQPVWRADRPQKGRYREFYQCDADVVGSNSLLNEVELVQMIDRVFGKFGVRVSIKINNRKILTGIAEIIGEADKIVDITVAIDKLDKIGLENVNAELASKGIPQEAIDKLQPIILLSGSNEEKLETLKTVLATSEAGLKGVEESEFILKTVSALGVKSEVELDLTLARGLNYYTGAIFEVKALDVQIGSISGGGRYDNLTGVFGMDGMSGVGISFGADRIFDVLNQLDLYPKEAVNGTELLFVNFGDKEAAYCLPILTKVREAGVRAEIYPDASKMKKQMGYANDKQIPFVAIVGENEMNEGKLTLKNMTTGEQSLVTPDELLAVVKA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RM24_DANRE
Sequence: MRLTALLSMAAKVALPHGYRYGTNRPWTIAARRLNPPGKRRRKVFVEPIANEDWPVVRGDTVEVLSGKEKGKQGKVAQVIRARNWVILEGLNTHYRYVGRSGDYRGTYLASEAPLLLKDIALIDPTDRKPTEIQWRYTEEGERVRVSVRTGRIIPKPVFQRKDGIVPQQWKDGPKDTSPEDTLQKTYTPSLKTLEEEVMEKMNIQENRRPRKSYWY
What are the official names of this protein?
Probable 39S ribosomal protein L24, mitochondrial, L24mt, MRP-L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TTDR_ECOLI
Sequence: MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM
What is the function of this protein?
Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol.  Induces expression of the ttdA-ttdB-ygjE operon.
What are the official names of this protein?
HTH-type transcriptional activator TtdR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: NRDR_MARMS
Sequence: MRCPFCGTQDTKVVDSRLVSEGAQVRRRRTCIHCQERFTTFEVAELQMPKLIKSDGSREAFDEDKLRNGIIKAIEKRPVSIEAVETAITRIKEKMQATGERELPSRWTGEAVMEELQRLDQVAYVRFASVYRSFKDISEFREAIDRLESHSVSIPKSKKTAPESKKEDQA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ALKB5_XENTR
Sequence: MSATYTDLREKLQSLYRDSPKEVRKRKQPTSDTEEEEAASEPEEEEEARKVRSGIRQVRLFSPDECARIEAKIDEVVSRAEKGLYREHTVDRAPLRNKYFFGEGYTYGAQLQRRGPGQERLYPKGEVDEIPAWVNELVIRRLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVFFLPVQRGSVTVLSGYAADEITHCIRPQDIKERRAVVILRKTRTEAPRLEMKSLSSSYQPERLQGSNRQHILKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPKQRRRSHFSSENYWRRSHDYVDTYTETGEDDGSPVRKVKMRRH
What is the function of this protein?
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes.  Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro) (By similarity).  Requires molecular oxygen, alpha-ketoglutarate and iron (By similarity).  Demethylation of m6A mRNA affects mRNA processing and export (By similarity).
What are the official names of this protein?
RNA demethylase ALKBH5, Alkylated DNA repair protein alkB homolog 5, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5.
What is the protein family that this protein belongs to?
Belongs to the alkB family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: UREF_PSEAB
Sequence: MNSIWARLRLASSQLPIGGYSYSQGLEAALDNGWVRDAESARTWLVDQLQLNLARFEAPLLAGLLRAALIGDWAACDAASERHRASRETRELAQESRQMGFSLHQLLEALPELDAPGRAWLARQDPPNLAAAWAMAARAWRLDAEEALSAWFWSWLENQLAVLMKTLPLGQLAAQKLASSLLPELDRACAEALRRPAVEGSAAFGLALASMTHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAH_HORVU
Sequence: MASLVAVQPAAVKGLSGSSISGRKLAVRPSSAAVSRSTRRARGAAVVAKYGEKSVYFDLDDIANTTGQWDLYGSDAPSPYNGLQSKFFNTFAAPFTKRGLLLKFLLIGGGSLVAYVSASASPDLLPIKKGPQLPPTPGPRGKI
What is the function of this protein?
Possible role could be the docking of the LHC I antenna complex to the core complex.
What are the official names of this protein?
Photosystem I reaction center subunit VI, chloroplastic, PSI-H, Light-harvesting complex I 11 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the psaH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: BLA1_STEMA
Sequence: MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
What is the function of this protein?
Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring.
What are the official names of this protein?
Metallo-beta-lactamase L1 type 3, B3 metallo-beta-lactamase, Beta-lactamase type III, Metallo-beta-lactamase L1 type III, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: XB35_ARATH
Sequence: MGQQQSKGELLYQQVSYGNSEGIRALHRDGGDLEWMDREGKTPLILACMNSELFDVAKTLIELGSNVNAYRPGRHAGTPLHHAAKRGLENTVKLLLSHGANPLVLNDDCQTPLEVARVKGFSNVVRAIEKHICLFSGWMREFYGPTFLDLFAPQLLSRRVWVVIVPTGSRNPTKPFKLELVVYASLQDAQPRTVMPLWKANLEEPKAKQSDTSVMIVDNSTIPSRRMKKRRVCASHGRRRPQVVRQTRLKFAPSTEGDSQQLKWFCDACKGIPQPMHPPVFLQAPPSAPPPPSEDGLAMGMNASLHTTMSDPSNLNHHSIGQASSSSGPSSSTAPPSGKASAFGFNSHGIGIVLESSPSAPPLTDDDIATVDDGPIHYPSIDSTPVDLPSAASLPASTEGERKEDGNTGTCAICLDAPSEAVCVPCGHVAGCMSCLKEIKSKNWGCPVCRAKIDQVIKLYRV
What is the function of this protein?
No E3 ubiquitin-protein ligase activity observed when associated with the E2 enzyme UBC8 in vitro.
What are the official names of this protein?
Putative E3 ubiquitin-protein ligase XBAT35, Ankyrin repeat domain and RING finger-containing protein XBAT35, Protein XB3 homolog 5, RING-type E3 ubiquitin transferase XBAT35.
Protein: LPOA_EDWI9
Sequence: MLSSITVRTKSGRLIPLVLAATLLAACSGRISTTPPAPVQSEATASADYYLQQMQQSSDDSKADWQLLAIRALLREGKLPQADDLLGQLPSQLTEAQQLEQRLVSAELEIARHAPQQAQAILSKLDISLLSQAQQLRYYQAVIAAVQGKTTLAQIRAYIALQPLLTQENQRKSNIDATWTALNTLTPADLNSMVINANEDILRGWLDLLRLYQDNRQDPALLKAAIKEWQTRYPNNPAATMLPSALDNILHLQSDSTASIALLLPLNGQAKVFSDAIEAGFNAAKNGAFNQNSAAVTTDGTPTAQVDAPAQPDVNAAGAVSTSTQSADATASVLPADSAALPPLDAAGDPIAPSVSPGNPDAHIQVYDTSSQPLPELLSQAQQAGVSLVIGPLLKNNVDQLNTISTPLNILALNQPEQVQNHPNICYFALSPEDEARDAARHIWAQGKRTPLLLIPRNPLGDRVAKAFATEWQSLGGGSVLRQTFGSSAELRSTINSGTGIRLTGQPVSITPAQPTSVTIAGLTIPAPVQPPVASGGGVDAVYIIATPAEITLIKPMIDLANGTHNGISLYASSRSYQAGAGPDFRLEMEGVQFSDIPLLAGSDPAILQQAPAQYRNDYSLMRLYAMGADAWTLANHFAQLRQIPGFQVQGATGTLSASDNCVIQRKLPWLQYQKGSIVPVL
What is the function of this protein?
Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).
What are the official names of this protein?
Penicillin-binding protein activator LpoA, PBP activator LpoA.
What is the protein family that this protein belongs to?
Belongs to the LpoA family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: TSAD_YERP3
Sequence: MRVLGIETSCDETGIAVYDDKAGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEANLSAKDIDAVAYTAGPGLVGALLVGATIGRALAFAWGVPAVPVHHMEGHLLAPMLEENAPEFPFVALLVSGGHTQLISVTGIGEYLLLGESVDDAAGEAFDKTAKLLGLDYPGGPMLSRMAQQGTVGRFTFPRPMTDRPGLDFSFSGLKTFAANTIRANGDDDQTRADIARAFEDAVVDTLAIKSKRALDQTGFKRLVIAGGVSANQTLRLKLADMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLRSNLNSELSVSVRPRWPLSELPKV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPB_AERHH
Sequence: MTLLNPFFGEFGGMYVPQILIPALLQLEKAFVDAKDDPAFIAEFQTLLTEYAGRPTPLTLTRNLTKGTKTRLYLKREDLLHGGAHKTNQVLGQALLAKRMGKSEIIAETGAGQHGVATALACALLGLKCRVYMGAKDCERQKPNVFRMKLMGATVIPVHSGSSTLKDACNEALRDWAANYESAHYLLGTAAGPHPFPTIVREFQKMIGEEAKAQCFEKEERLPDAVIACVGGGSNAIGMFADFIDEPSVRLIGVEPGGHGIESGEHGAPLGHGSKGVFFGMHSYLMQDTQGQIQESYSVSAGLDFPSVGPQHAHLAAIGRAEYPSVTDKEALDAFQELAKSEGIIPALESSHALAHALKMARSEPEKEQVLIVNLSGRGDKDIFTVADIFEKEGTLS
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: GATC_RICCN
Sequence: MITKEEAQKIAKLARLKFEEDTVEKFFTQLSTIMDMIDILNEIDCKDIEPLTSVCNMNARMREDAVTSSDLSSELLDNVSGNSAQLAKEVKYFITPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: CHX17_ARATH
Sequence: MGTNGTTCPGPMKATSNGVFQGENPLEHALPLLILQICIVLLLTRLLAFLLRPLRQPRVIAEIVGGILLGPSALGKSTKFINTVFPPKSLTVLDTLANLGLIFFLFLVGLELDPKSLKRTGKRALSIALAGITLPFVLGIGTSFALRSSIADGASKAPFLVFMGVALSITAFPVLARILAEIKLLTTDIGKIALSAAAVNDVAAWILLALAVALSGEGSSPLTSLWVFLSGCGFVLFCIFVVQPGIKLIAKRCPEGEPVNELYVCCTLGIVLAASFVTDFIGIHALFGAFVIGVIFPKEGNFANALVEKVEDLVSGLFLPLYFVSSGLKTNVATIQGAQSWGLLVLVIFNACFGKIIGTVLVSLYCKVPLDQSLALGFLMNTKGLVELIVLNIGKDRGVLNDQIFAIMVLMAIFTTFMTTPLVLAVYKPGKSLTKADYKNRTVEETNRSNKPLCLMFCFQSIMNIPTIVNLIEASRGINRKENLSVYAMHLMELSERSSAILMAHKVRRNGLPFWNKDKSENNSSSSDMVVVAFEAFRRLSRVSVRPMTAISPMATIHEDICQSAERKKTAMVILPFHKHVRLDRTWETTRNDYRWINKKVMEESPCSVAILVDRGLGGTTRVASSDFSLTITVLFFGGNDDREALAFAVRMAEHPGISLTVVRFIPSDEFKPENVRIEITEDQLCSGATRLIDIEAITELKAKIKEKESSRSNSDSESHIIYEEKIVKCYEEVIEVIKEYSKSNLFLVGKSPEGSVASGINVRSDTPELGPIGNLLTESESVSTVASVLVVQQYIASRPVGISKNVTTEESLVEDSESP
What is the function of this protein?
Operates as a K(+)/H(+) antiporter that controls K(+) acquisition and homeostasis.
What are the official names of this protein?
Cation/H(+) antiporter 17, Protein CATION/H+ EXCHANGER 17, AtCHX17.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YEAD_SALTY
Sequence: MINKIFALPVIEQLTPVLSRRQLDDLDLIVVDHPQVKASFALQGAHLLSWKPVGEEEVLWLSNNTPFKTGVALRGGVPICWPWFGPAAQQGLPSHGFARNLPWALKAHNEDDNGVMLTFELQSSEATRKYWPHDFTLLARFKVGKTCEIELEAHGEFATTSALHSYFNVGDIANVKVSGLGDRFIDKVNDAKEGVLTDGIQTFPDRTDRVYLNPEACSVIHDATLNRTIDVVHHHHLNVVGWNPGPALSVSMGDMPDDGYKTFVCVETVYATAPQQATEEKPSRLAQTICVAKR
What is the function of this protein?
Probably functions as a hexose-6-phosphate 1-epimerase.
What are the official names of this protein?
Putative glucose-6-phosphate 1-epimerase, Putative D-hexose-6-phosphate mutarotase.
What is the protein family that this protein belongs to?
Belongs to the glucose-6-phosphate 1-epimerase family.
Protein: MFTC_CRIGR
Sequence: MTGQGQPAAGSAAWSTVFRHVRYENLVAGVSGGVLSNLALHPLDLVKIRFAVSDGLEVRPKYKGILHCLTTIWKVEGLRGLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGRAEQLEPLEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYGGVVNPSQRQYKGMFDALVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYELLKLEYNKHINRLPEAQLSTPEYISVAALSKIFAVAATYPYQVVRARLQDQHVSYGGVMDVIVKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFLCGLREKKVS
What is the function of this protein?
Transports folate across the inner membranes of mitochondria (PubMed:15140890, PubMed:17279620, PubMed:21768094).  Can also transport FAD across the mitochondrial inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial folate transporter/carrier, Solute carrier family 25 member 32.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DOIS_STRSD
Sequence: MQTTTITMGDVQYPYRLGTGCVDGIVTRLGELEASHYLVLCDATVAELYGHDLAARLRRSAGPASVLTHPAGEEHKGLGTLDTLADAALHAGVDRRGVVVALGGGVTGNIAGLLAALLFRGIRLVHVPTTVVAMLDSVLSLKQAVNAQVGKNLVGTFYPPVEVLADTAMLGTLPVREIRSGLCEVVKNALAIRPSMIDFLAAELRPDGRYADDVLRWMIDESVAAKAQVTEHDKYERREGLVLEYGHTVGHALEHASHGAVSHGAGVGVGMVAAAEVARRLGHVDADLVELHRELVGKVGVATTLPADVPTEEITYRLGFDNKRGYQPLPADHYAMVLLADVGQPLYQDGLPLTPAPRALVDEVVRELADAPSRIGASVGSAGGAS
What is the function of this protein?
Catalyzes the intramolecular carbocycle formation from D-glucose-6-phosphate to 2-deoxy-scyllo-inosose (DOI).
What are the official names of this protein?
2-deoxy-scyllo-inosose synthase, DOI synthase, DOIS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. DOI synthase family.
Protein: SYV_BORGP
Sequence: MNFRLLEKYDPKAFEDEIYNKWLKNNVFLPNNSLFEKFSMVAPPPNVTGVLHMGHALNFVLQDILVRYKRMKKHNTLWLFGTDHAGIATQTVFERNLKNIGKSKNDFEREEFVKEIFKLKDKHRGVIVNQIKKLGASYDHSRERFTLDESLCKAVNKVFKDLYSKGLIYRGEYLVNLDPGSGSVVSDEEIEYKEVDGKLYFVKYFIDDSSFIEIATTRPETMFGDTAIAVNPNDERYKSLVGKEVTIPLTTKKIKIIADFHVDSAFGTGALKITPAHDPNDFEISKRHNIPKVNILTQDGKLNENVPLQYQGLSIKDARFKIEIELMEKGFLKGVKKHRQQVGHCYRSGEVIEPYLSTQWFVSMKPLAEKALKALESGELRFYPKKWENTYKYWLSNIKDWCISRQLVWGHRIPAWYNIDTSELIISDTDPSLDEKNVGKRFVQDPDVLDTWFSSWLWPFSSLGWPNITVDFENYYPTKTLITAYDIIFFWVARMVMAGLEFTGQTPFRDVYITPLLRDKQGKKMSKSLGNGIDPLDIIHEYGSDSLRFTLSFLSVQGQDLNIDAKDFMLGAKFANKVFNASKFILLNLENREIFNNLKFNDIDKWLLTSLNSTILGVESSFANYKYNEASKFVYEFFWNDFCDWYIEISKIDLNSENVDIQNMAISKLLFFLKKALLILHPFIPFVTEKIYSEFSEKGDILALNEYPSFDISSNFKEEFESFKVFKTFIVAVRTLKSEFNISSSIEIDVALKFDSDFKYEGYFKANESISKRMINFKNIFYNENCDGMLGLAVVGFEIYADVKLLIDKTKELIRLEKQLEKYKMLKISVSKKLENENFLMNAPKEIIESEKLKFVEFSSLINKINSYIINLKNL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STX1A_RAT
Sequence: MKDRTQELRTAKDSDDDDDVTVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIIIASTIGGIFG
What is the function of this protein?
Plays an essential role in hormone and neurotransmitter calcium-dependent exocytosis and endocytosis (PubMed:7901002, PubMed:17301173, PubMed:18167541, PubMed:20484665, PubMed:22411134, PubMed:28813412).  Part of the SNARE (Soluble NSF Attachment Receptor) complex composed of SNAP25, STX1A and VAMP2 which mediates the fusion of synaptic vesicles with the presynaptic plasma membrane (PubMed:14665625, PubMed:16888141, PubMed:19571812).  STX1A and SNAP25 are localized on the plasma membrane while VAMP2 resides in synaptic vesicles.  The pairing of the three SNAREs from the N-terminal SNARE motifs to the C-terminal anchors leads to the formation of the SNARE complex, which brings membranes into close proximity and results in final fusion (PubMed:14665625, PubMed:16888141, PubMed:19571812).  Participates in the calcium-dependent regulation of acrosomal exocytosis in sperm (By similarity).  Also plays an important role in the exocytosis of hormones such as insulin or glucagon-like peptide 1 (GLP-1) (By similarity).
What are the official names of this protein?
Syntaxin-1A, Neuron-specific antigen HPC-1, Synaptotagmin-associated 35 kDa protein, P35A.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell membrane. Synapse, synaptosome. Note=Colocalizes with KCNB1 at the cell membrane (PubMed:17301173). Colocalizes with PLCL1 at the cell membrane (PubMed:22673903).
Protein: GRPE_CARHZ
Sequence: MEEKDKEEKVTGENLEPEDKNLEQEDKEEVVGPQEEQQIDEAKNWEEEYNKLLDEHNRLKNQYLRLYADFDNYRKRTQREKEELLKYEGMEFLKKLLPVLDNFERALKEKDTDPQKVIEGVELTHRQLLEILNQHEVKAIEAQGQPFNPELHEALMVEVREDLEENTVIEELVKGYFYKDKVLRPALVKVSKKQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.