PharMolix/UniProtQA huggingface dataset:
Protein: FTSH_HELFC
Sequence: MDNNHKGPNDPNSKKPLLQNPLLLIAIFGIIIFVAMRVMNSDEGFGDRFLSTSTKNISYHEMKELIEKKEVDSVSIGQTLIKAISKEGNNKTIYVAKRVPDLSLVPLLDSQKINYSGFSESNFFADILGWLLPVLVILGLWMFMASRMQKNMGGGIFGMGSSKKLINAEKPKVRFNDMAGNEEAKEEVVEIVDFLKYPDRYASLGAKIPKGVLLVGPPGTGKTLLAKAVAGEASVPFFSMGGSSFIEMFVGLGASRVRDLFDIAKKEAPSIIFIDEIDAIGKSRAAGGMISGNDEREQTLNQLLAEMDGFGSENAPVIVLAATNRPEILDPALLRPGRFDRQVLVDKPDFKGRVEILKVHIKPVKLANDVDLQEIAKLTAGLAGADLANIINEAALLAGRNNQKEVKQQHLKEAVERGIAGLEKKSRRISPKEKKIVAYHESGHAVISEMTKGSARVNKVSIIPRGMAALGYTLNTPEENKYLMQKHELIAEIDVLLGGRAAEDVFLQEISTGASNDLERATDIIKGMVSYYGMSDVSGLMVLEKQRNSFLGGGFGSGREFSEKMAEEMDSFIKNLLEERYVHVKQTLSDYKDAIEVMVNELFEKEVITGERVREIISEYEVSHNLQTRLVPLEEHAS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: MRAY_ECODH
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQLVVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECA_HAEIN
Sequence: MATQEEKQKALAAALGQIEKQFGKGSIMKLGDTKTLDVESISTGSLGLDVALGIGGLPMGRIVEIFGPESSGKTTLTLSVIAQAQKAGKTCAFIDAEHALDPIYAAKLGVDVKELFVSQPDNGEQALEICDALVRSGAIDVIIVDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTGQIKNANCLVVFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRTGSVKDGENIIGNETRVKVVKNKLAAPFRQVDFQILYGEGISKAGELLELGVKHKLVEKSGAWYSYNGEKIGQGKANSMKWLNENIEKSDELEARLRAELVANPEQALMADIEQSENNTESESDFE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.  Plays a central role in DNA metabolism, participating in general homologous recombination, recombinational (postreplication) DNA repair, and prophage induction.
What are the official names of this protein?
Protein RecA, Recombinase 1, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_RICAE
Sequence: MADLAKIEEQLSSLTLMQAAELVKILEEKWGVSAAAPVAVAAAGAAAPAAEAVAEKTEFEVVLTAAGDKKVEVIKVVKDITGLGLIEAKKLVDEAPKPIKSNVKKADADEIKGKLEAAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: YFEO_ECOL5
Sequence: MLHPRARTMLLLSLPAVAIGIASSLILIMVMKIASVLQNLLWQRLPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPGLIVALILGLAGGVSLGPEHPIITVNIALAVAIGARLLPRVNRMEWTILASAGTIGALFGTPVAAALIFSQTLNGSNEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQMEMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVFVLGIGGLILGILGVIGGPVSLFKGLDEMQQMVANQAFSTSGYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVALGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVMLPAWLLLAGKPMMMVNRQKQQPPHDNV
What are the official names of this protein?
Putative ion-transport protein YfeO.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSCA_SHEB9
Sequence: MALLQIAEPGQSAAPHQHRLAVGIDLGTTNSLVAAVRSGETATLPDELGQHSLPSIVRYTQDSVEVGALAALSSAQDPQNTIVSVKRFMGRSLADIKAGEQSFPYEFAESENGLPLFVTPQGQVNPVQVSAEILRPLIARAEKTLGGELQGVVITVPAYFDDAQRQGTKDAAALLGVKVLRLLNEPTAAAIAYGLDSKQEGVIAIYDLGGGTFDISILRLNRGVFEVLATGGDSALGGDDFDHLLQAHMQQVWQLSDIDSQLSRQLLIESRRVKEALTDAAETEAKVILADGTELTQIVTKAEFDAMIAALVKKTIASCRRTLRDAGVTTDEVLETVMVGGSTRVPLVREQVEAFFGKPPLTSIDPDRVVAIGAAIQADILVGNKPESDLLLLDVIPLSLGIETMGGLVEKVVSRNTTIPVARAQEFTTFKDGQTAMAFHVVQGERELVADCRSLARFTLKGIPPLAAGAAHIRVTFQVDADGLLSVTAMEKSTGVQSSIQVKPSFGLSDTEIATMLKDSMKYAKDDIGRRMLAEQQVEAARVLESLHAALAKDGDLLNADERGQIDAIMANVAQVAAGDDADAIKLAIEKLDEQTQDFAARRMDNSIRVAFKGQSIDNI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: YUC4_ARATH
Sequence: MGTCRESEPTQIFVPGPIIVGAGPSGLAVAACLSNRGVPSVILERTDCLASLWQKRTYDRLKLHLPKHFCELPLMPFPKNFPKYPSKQLFISYVESYAARFNIKPVFNQTVEKAEFDDASGLWNVKTQDGVYTSTWLVVATGENAEPVFPNIPGLKKFTGPVVHTSAYKSGSAFANRKVLVVGCGNSGMEVSLDLCRYNALPHMVVRNSVHVLPRDFFGLSTFGIAMTLLKWFPLKLVDKFLLLLANSTLGNTDLLGLRRPKTGPIELKNVTGKTPVLDVGAISLIRSGQIKVTQAVKEITRNGAKFLNGKEIEFDSIILATGYKSNVPDWLKENSFFTKEGMPKTPFPNGWKGEKGLYTVGFTRRGLSGTAYDAVKIAEDITDQWMKFNGPLSCRNICSSHIIHLHFNKS
What is the function of this protein?
Involved in auxin biosynthesis.  Both isoforms are catalitically active.  Involved during embryogenesis and seedling development.  Required for the formation of floral organs and vascular tissues.  Belongs to the set of redundant YUCCA genes probably responsible for auxin biosynthesis in shoots.
What are the official names of this protein?
Probable indole-3-pyruvate monooxygenase YUCCA4, Flavin-containing monooxygenase YUCCA4.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: OBG_METPP
Sequence: MKFVDEAYIDVIAGNGGNGCVSFRREKFIPFGGPNGGDGGRGGSVYAVADRNLNTLIDFRFARRHEARHGEHGRGSDQFGAAAEDIVMRMPVGTIISDAETGAPVAELLEPGERILIAKGGDGGFGNLHYKTSTNRAPRQKTPGWPGEQKKLKLELRVLADVGLLGMPNAGKSTLISAISNARPKIADYPFTTLHPNLGVVRVGPEQSFVVADVPGLIEGAAEGAGLGHRFLRHLQRTRLLLHMIDMAPFDDTDPVAQAKAIVAELKKYDPALYDKPRWLVLNKLDVVPAEERAARVKDFVKRFKWKGPVFEISALTREGCETLVQAIYQHVASYQTHYVDPDVRFAEPEADESDDEPRFAPQADDPRFR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_YERPY
Sequence: MSLGALISESRNPATMELDKLSTLAMLTCINDEDRKVPDAIRLVLPAVAQAVDLAADALKQGGRLIYLGAGTSGRLGVLDASECPPTFGVPHGMVIGLIAGGPGALLKAVEGAEDDIALGMRDLQDLQLTATDMVVGLAASGRTPYVIGALRYARELGCPTAAISCNPDSPIAQEAQVAISPVVGPEALTGSTRMKSGTAQKLVLNMLSTGAMVKLGKVYQNLMVDVKATNVKLVDRACRIVVEATGVSRAEAEHALRQTDFEVKPAILMLLKGVSAEQARQDLRQHHGYLRAAL
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: ECFA2_STRPB
Sequence: MSINLQNVSYTYQAGTPFEGRALFNINLDILDGSYTAFIGHTGSGKSTIMQLLNGLHVPTTGIVSVDKQDITNHSKNKEIKSIRKHVGLVFQFPESQLFEETVLKDVAFGPQNFGVSPEEAEALAREKLALVGISENLFEKNPFELSGGQMRRVAIAGILAMQPKVLVLDEPTAGLDPKGRKELMTIFKKLHQSGMTIVLVTHLMDDVANYADFVYVLDKGKIILSGKPKTIFQQVSLLEKKQLGVPKVTKLAQRLVDRGIPISSLPITLEELREVLKHG
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: WDR59_SCHPO
Sequence: MRELQGDDSSRKSPPSDSVVKNSSPIDYEHSLKSLQDERTLNYPNKQFNSENPSSYYNMDDSGELCNFELEKDSLESMIHESSTALSAQSNTAQDGDQLASSSTISKDHSETLDNKLNDSKILIKKASNSFANFSESVRSSTIVAYSQTPTQRLQGLTSISSSSFDDGSYGSRRISFNSQGVSGRLRRNMDSTVIIPSEDEDLQLPSNSNSNVEYGPFDSTTFDRQLSIEVNQPVGAMSLSPCGRDIALASRYGLLVLDLDNPYNPPRMLRHSTPWEVADTQWNVHAARDQWVVSTSSQKTIVWNLALPNDRAIEFMLHGHTRAVTDMNWHRQNPDVLATCSIDSSVHCWDLRSPRFPVNSFYDWHNGATQVKWNYKNPHILASSHGRLVRIWDDRYGSAPLHTIKTSENITKINGLEFNRACETRLLTCAMDRTVKFWNYEKSTEEPEHLITTDSPVWKARFTPFGDGVILMPQRGDNSVHMYDCRNLDKEGPRAVHRFAGHTDQVKEFLWRCRGEDVFDRDLRDFQLITWSKDHHVRLWPIGNDILNSMGHDRTKPVPFKLTRLGAKYRTYSREPLKQSLINTECDSSDAMNSFDSNFGAERANTSDLSRGFVAFANRKKSKYNLPGSSGFMTRSTKSTNPMTPLNWLRGISMGRLGNADWEVPQNLGEELSWIGQKYSNVSFEKIDVAERTCTISLNAPILPDDGYAYIRLHVYFPNNYPISATPVFQLERSSAFNDEQFNYVFNTLTSISDQCISSHKYCMDACLSYLSGNLSVDEIWKLGFQKDNSDSSSESSADIFQDVFPSMPDFRGGDRGLSHKHQNIPLPKTCAAIFCGNDELVCFFTIKADESAAQATANRETHGRQKLFESFGVLDSSNSVADSDSTNYDDENSLNRGGTSESDSEFIWDVDESNSGSIVFPKSKTSINLNNINSASASIMGSRFGAADIFMSKRPSTKGSNRPSILLSKPSHDFHVVRIISMSKYLPVKRALAAEYVVDTGDKVTVCNKNAEVSAKHNYYRLAKVWLMLGRLLGHLSRTENKDHINDEEAFPWLKSPLAKWVVNSLLDYYASQCNTQMLAMLACVLDIPNPKKQSGNTSADQVLFNQPKQVTEKLGVQLNLPKTKILEKVSSHSLAQITALREKEPKDADSTYSKEKIFSATSTVHLQLMDYDKQNNDFVDAQEIAYTKLLQQKFIQWRATYAEQLDLWGFFIPKLEMLKFNAHEFSSPSEKTLVNHCNSCNSTTSNTRICEKCYSLVPRMSCTFCCLSIHGLCIVCGLCLHVMHEDCYKEWFSNGDSISQSCSSGCGCKCQFQHMSLEKV
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Uncharacterized RWD, RING finger and WD repeat-containing protein C11E3.05.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR59 family.
Protein: HSCB_SHEAM
Sequence: MNYFELFNLPVAFDVNTSELADKYRELQRTVHPDKFAAASEQEKLLAVSRTAMVNDGFQTLKDPIRRAEHMLALKGVDIRHETQTVRDTAFLMQQMEWREALEEITHADDPHCLIADLYQSFGDFQKQVTAKLKTLLVSEDDNDLQAAADQVRKLKFMAKLHVELERAEDALLD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: I1B7_CONRA
Sequence: GPSFCKADEKPCEYHSDCCNCCLSGICAPSTNWILPGCSTSSFFKI
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  Produces general excitatory symptoms (By similarity).
What are the official names of this protein?
Iota-conotoxin-like R11.7.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IMAND_CATAD
Sequence: MTDANHLLDPSGALPQTRPPWTSRDSLRITRVRAIVTAPEGQPLVVVRVDTSDDGLYGLGCATFTQRYAAVAAAVDEHVGPLAVGRHPADIEDITRLIHYSSYWRSGPVLNNALSGLDQALWDIAGKRAGMPVYELLGGRSRSAVEVYSHAAGGTIEATLDQAEELLAEGYRNVRLQLGGPGLGTYGAPGTLGGYPRSPHPDGWAVEQYLRDAPRLFAAARERLGDSVNLMHDVHSRLTPKQAVVLARALEPYRLSFLEDVIAPELYDRLPEVRAASPVPIAVGEQIGSVPDAVRLVRDGGVDLLRLHTSAVGGLTPTRKIVALCELLGVRTAFHSPADVSPVGVAANLAVDISTPAFGYQESHTYNDATHEVFPGTRVVREGHLYPAEEPGWGIEIDERAAAKFPPVKFLHERWSSGVRRPDGGLEAP
What is the function of this protein?
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding.  May have evolved a divergent function.
What are the official names of this protein?
D-galactonate dehydratase family member Caci_4410.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: NTPP_MYCMM
Sequence: MTRLVLGSASSGRLKVLQQAGVDPLVVVSGVDEDAIMAGLGPAATPADVVRVLARAKAEQVATTLTGQQASVATDCLVIGCDSMLYIDGRLCGKPETVDDARQLWRSMAGRCGHLYTGHSVVRLTEQRVTHRDDETSTTTVHFATPSDDDLEAYLATGESLKVAGGFTLDGLGGWFITGVEGDPSAVVGIGLPLTRDLISRAGISIAALWASNPLP
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBZ_CRYJA
Sequence: MTIAFQSSVFALIAISTLLVIGVPVALASPNGWSSNKNVLFSGVSLWIGSVFLVGILNSFIS
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: DBH_BORAF
Sequence: MSFPRRPKVTKSDIVDQISLNIRNNNLKLEKKYIRLVIDAFFEELKSNLCSNNVIEFRSFGTFEVRKRKGRLNARNPQTGEYVKVLDHHVAYFRPGKDLKERVWGIKG
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HBbu.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: AQP7_MACFA
Sequence: MVQTSRHRRSTRGSKMVSWSVMAKIQEILQKKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGHISGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYTLFYTAILHFSGGQLMVTGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNAALPGTQALVIGILVVIIGVSLGMNTGYAINPSRDLPPRVFTFIAGWGKEVFSEGENWWWVPVVAPLLGACLGGIIYLVFIGSTTPREPLKLEDSVAYEDHGITVLPKMGSHEPTISPLTPVSVSPANRSSVRPAPPLHESMALGHF
What is the function of this protein?
Forms a channel that mediates water and glycerol transport across cell membranes at neutral pH (By similarity).  The channel is also permeable to urea (By similarity).  Plays an important role in body energy homeostasis under conditions that promote lipid catabolism, giving rise to glycerol and free fatty acids.  Mediates glycerol export from adipocytes.  After release into the blood stream, glycerol is used for gluconeogenesis in the liver to maintain normal blood glucose levels and prevent fasting hypoglycemia.  Required for normal glycerol reabsorption in the kidney (By similarity).
What are the official names of this protein?
Aquaporin-7, AQP-7, Aquaglyceroporin-7.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm, cell cortex. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Lipid droplet. Note=Internalized from the cell membrane in response to catecholamine-induced activation of PKA; detected on intracellular membranes and colocalizes with lipid droplets (By similarity). Colocalizes with PLIN1 in adipocytes, probably on lipid droplets (By similarity).
Protein: DXR_PORG3
Sequence: MKKNIAILGSTGSIGTQTLDIIHLNPDLFDVYLLTANNNVDLLIRQAREYRPEIVVIANDQKYHLIQEALADLPIKVWCGAEAIADAVTAPDIDMVVTAMVGYSGLLPTIKAIEARKMIALANKETLVVAGELIMRLAQDNQVPILPVDSEHSAIFQALLGERQRPEKILLTASGGPFLHLTAEELQHATREQALRHPNWNMGAKVTIDSASLMNKGFEMIEAKWLFEMQPDEIEILVHPQSIIHSMVQFRDGSVKAQLGIPDMRLPISYALGITHRIPNDYPRVDFTATPLTFERPDLERFPNLSYAFDAIRLGGNAPCALNAANEIAVTAFLRDEISFTDMSRLLYEVMEKHELFREVSLPTFIETDSNTRRVAESLLPKFRR
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: MOBA_BACVZ
Sequence: MKRVNVILAGGASRRFGEPKAFAKWKGGMFYEQAKKAFGGGETVIISRPEHIKKFLSNRERHVLADEPRFRGMGPLAGIYTAMKQTEGETFTVISCDTPLVTRKTMVALEMKLTGNLDAVIPVCKNREQPLLAVYHKRVQDVLFDQLTQNKLKMTDTLKRLSVCYVQAEDIGAGPEEFANINTQDDYTRLLAHVESSNQD
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_CAMC1
Sequence: MNEVVAKKYVKAILSDVKSNELNAFVENLSELAAAFASDKFKSIISLPTLKASQKVEFVLSLVKNQDAKFANFIKLLGANKRLELIPAILDEMKIEQSLLENTYRGEVVGNFDLSAEQLKALEENFSKKFNSKIKLDGSKSDYNGVKVELDDLGVEVNFSIDRLKSQMSEYILKAI
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DYM_RAT
Sequence: MGSNSSKISDLPKNEYLKRLSGPEAISENDPFWNQLFSFSFSAPTSSTELKLLEEATISVCKSLVENNPRTGNLAALTKVFLARTRELRLSAECQNHIFIWQTHNALFIICCLLKVFICEMSEEELQLHFTYEEKLPGTYTLCVLLGSDSEDLLEELLCSLIQLITDTPLLDITYEISVEAISAMIVFLSCQLFHKEVLRQSISHKYLMQGPCLPYTSKLVKTLLYNFIRQEKPPPPGTHVFPQQSDGGGLLYGLASGVATGLWTVFTLGGVGSKAASPELTSPLANQSLLLLLVLVNLTDAPDIPNPYRQAVTSFKNTQDSSPFPSSVPHTFQINFNSLYTTLCEQQTSDQATLLLYTLLHQNANVRTYMLARTDMENLVLPILEILYHVEERNSHHVYMALIILLILTEDDGFNRSIHEVILKNITWYSERVLTEISLGSLLILVVIRTIQYNMTRTRDKYLHTNCLAALANMSAQFRSLHQYAAQRIISLFSLLSKKHNKVLEQATQSLRGSLSSSDVPLPDYAQDLSVIEEVIRMMLEIINSCLTNSLHHNPNLVYALLYKRDLFEQFRTHPSFQDIMQNIDLVISFFSSRLLQSGAELSVERVLEIIKQGVVALPKDRLKKFPELKFKYVEEEQPEEFFIPYVWSLVYNSAVGLYWNPQDIQLFAMDSD
What is the function of this protein?
Necessary for correct organization of Golgi apparatus.  Involved in bone development.
What are the official names of this protein?
Dymeclin.
What is the protein family that this protein belongs to?
Belongs to the dymeclin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Membrane; Lipid-anchor. Note=Sequence analysis programs predict 1 transmembrane region. However, it has been shown in human that it is not a stably anchored transmembrane protein but it weakly associates with the Golgi apparatus and shuttles between the Golgi and the cytosol (By similarity).
Protein: P4K2A_RAT
Sequence: MDETSPLVSPERAQPPEYTFPSVSGAHFPQVPGGAVRVAAAGSGPSPPCSPGHDRERQPLLDRARGAAAQGQTHTVAAQAQALAAQAAVAVHAVQTHRERNDFPEDPEFEVVVRQAEIAIECSIYPERIYQGSSGSYFVKDSQGRIIAVFKPKNEEPYGNLNPKWTKWLQKLCCPCCFGRDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEKVPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVLDYIIRNTDRGNDNWLIKYDYPMDNPNCRDTDWVMVREPVIKVAAIDNGLAFPLKHPDSWRAYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQIAVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
What is the function of this protein?
Membrane-bound phosphatidylinositol-4 kinase (PI4-kinase) that catalyzes the phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P), a lipid that plays important roles in endocytosis, Golgi function, protein sorting and membrane trafficking and is required for prolonged survival of neurons.  Besides, phosphorylation of phosphatidylinositol (PI) to phosphatidylinositol 4-phosphate (PI4P) is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3).
What are the official names of this protein?
Phosphatidylinositol 4-kinase type 2-alpha, 55 kDa type II phosphatidylinositol 4-kinase, Phosphatidylinositol 4-kinase type II-alpha.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Lipid-anchor. Membrane raft. Endosome. Cytoplasmic vesicle. Cell projection, dendrite. Presynaptic cell membrane. Synapse, synaptosome. Mitochondrion. Membrane; Lipid-anchor. Cell membrane. Perikaryon. Cell projection, neuron projection. Note=Found in subdomains of the plasma membrane termed non-caveolar membrane rafts. Transported from neuronal cell body to neuron projections and neurite tips in a BLOC-1- and AP-3- complexes-dependent manner.
Protein: RNC_BLOPB
Sequence: MLVNALQEKLGYIFNRYDLLLQALTHRSSSNQHNERLEFLGDAILNYVIANLLYHRFPHISEGGMSRMRANLVRENTLATLAREFNLGDYLQLGQGELKSGGYQRESILANTIEALIGGIFLDSNIQTIEILIINWYKIRIDHMDPYASYDTQKDPKTRLQEYMQRRRLPLPVYWINQIIGEAHNQIFTINCQVSELTQPIIGCGSSRRRAEQNAAAKVLEALEHNQNI
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSI7_STRAM
Sequence: SLHAPSALVLTVGHGESAATAVPLRAVTLTCAPTASGTHPATVSACAELRGAGGDFDALAADAGVMCTREYAPVVVTVDGVWQGRRLSYERTFANECVKNAGSSSVFTF
What is the function of this protein?
Strong inhibitory activity toward subtilisin BPN' and, to a lesser extent, toward trypsin.
What are the official names of this protein?
Subtilisin inhibitor-like protein 7, SIL-7, SIL7.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I16 (SSI) family.
What are the subcellular locations of this protein?
Secreted.