PharMolix/UniProtQA huggingface dataset:
Protein: RK2_ORYSI
Sequence: MAKHLYKTPIPSTRKGTIDRQVKSNPRNNLIHGRHRCGKGRNSRGIITARHRGGGHKRLYRKIDFRRNQKDISGRIVTIEYDPNRNAYICLIHYGDGEKGYILHPRGAIIGDTIVSGTKVPISMGNALPLTDMPLGTAIHNIEITRGRGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLVSQNCLATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGKAPIGRKKPTTPWGYPALGRRTRKRKKYSDSFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ENV_HV1C4
Sequence: MAMRAKGIRKNCQHLWRWGTMLLGMLMICSAAANLWVTVYYGVPVWKEATTTLFCASDAKAYDTEAHNVWATHACVPTNPNPQEVVLENVTENFNMWKNNMVEQMHEDIISLWDQSLKPCVKLTPLCVTLNCTDLNTNNTTNTTELSIIVVWEQRGKGEMRNCSFNITTSIRDKVQREYALFYKLDVEPIDDNKNTTNNTKYRLINCNTSVITQACPKVSFEPIPIHYCTPTGFALLKCNDKKFNGTGPCTNVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSENFTNNAKTIIVQLNVSVEINCTRPNNHTRKRVTLGPGRVWYTTGEILGNIRQAHCNISRAQWNNTLQQIATTLREQFGNKTIAFNQSSGGDPEIVMHSFNCGGEFFYCNSTQLFNSAWNVTSNGTWSVTRKQKDTGDIITLPCRIKQIINRWQVVGKAMYALPIKGLIRCSSNITGLLLTRDGGGENQTTEIFRPGGGDMRDNWRSELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGMLGAMFLGFLGAAGSTMGATSMALTVQARQLLSGIVQQQNNLLRAIKAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGFWGCSGKLICTTAVPWNASWSNKTLDQIWNNMTWMEWDREIDNYTHLIYTLIEESQNQQEKNQQELLQLDKWASLWTWSDITKWLWYIKIFIMIVGGLIGLRIVFAVLSIVNRVRQGYSPLSFQTLLPNPRGPDRPEGTEEGGGERGRDGSTRLVHGFLALVWDDLRSLCLFSYHRLRDLLLIVARIVELLGRRGWEVLKYWWNLLQYWSQELKNSAVSLVNVTAIAVAEGTDRVIEVVQRIYRAFLHIPRRIRQGFERALL
What is the function of this protein?
Acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane.  The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 env protein family.
What are the subcellular locations of this protein?
[Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag.
Protein: ODP21_ARATH
Sequence: MVLPLFRRAAIARTSSLLRARLFAPASEFHSRFSNGLYHLDDKISSSNGVRSASIDLITRMDDSSPKPILRFGVQNFSSTGPISQTVLAMPALSPTMSHGNVVKWMKKEGDKVEVGDVLCEIETDKATVEFESQEEGFLAKILVTEGSKDIPVNEPIAIMVEEEDDIKNVPATIEGGRDGKEETSAHQVMKPDESTQQKSSIQPDASDLPPHVVLEMPALSPTMNQGNIAKWWKKEGDKIEVGDVIGEIETDKATLEFESLEEGYLAKILIPEGSKDVAVGKPIALIVEDAESIEAIKSSSAGSSEVDTVKEVPDSVVDKPTERKAGFTKISPAAKLLILEHGLEASSIEASGPYGTLLKSDVVAAIASGKASKSSASTKKKQPSKETPSKSSSTSKPSVTQSDNNYEDFPNSQIRKIIAKRLLESKQKIPHLYLQSDVVLDPLLAFRKELQENHGVKVSVNDIVIKAVAVALRNVRQANAFWDAEKGDIVMCDSVDISIAVATEKGLMTPIIKNADQKSISAISLEVKELAQKARSGKLAPHEFQGGTFSISNLGMYPVDNFCAIINPPQAGILAVGRGNKVVEPVIGLDGIEKPSVVTKMNVTLSADHRIFDGQVGASFMSELRSNFEDVRRLLL
What is the function of this protein?
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
What are the official names of this protein?
Dihydrolipoyllysine-residue acetyltransferase component 1 of pyruvate dehydrogenase complex, mitochondrial, Dihydrolipoamide S-acetyltransferase component 1 of pyruvate dehydrogenase complex, Pyruvate dehydrogenase complex component E2 1, PDC-E2 1, PDCE2 1.
What is the protein family that this protein belongs to?
Belongs to the 2-oxoacid dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYGA_SYNP2
Sequence: MSLNFQEIIATLNQFWRDRGCLIAQPYDTEKGAGTMNHHTFLRAIGPEPWSVAYVEPCRRPTDGRYGENPNRVQHYFQYQVIIKPSPDNIQEIYLDSLKALGIQPEDHDIRFVEDNWESPTLGAWGVGWEVWLDGMEITQFTYFQQCGGLDCRPVCIEITYGLERLAMYLQEVDAITKIRWNETTSYGDIFLQSEIEQCTYNFEASNPEMLFQLFSLYEAEAQQLIEKGLVMPSLDYVLKCSHTFNLLDARGVIAVAERTRYIGRIRHMARQVAHLYLAQREELGFPLQKAIA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHX29_HUMAN
Sequence: MGGKNKKHKAPAAAVVRAAVSASRAKSAEAGIAGEAQSKKPVSRPATAAAAAAGSREPRVKQGPKIYSFNSTNDSSGPANLDKSILKVVINNKLEQRIIGVINEHKKQNNDKGMISGRLTAKKLQDLYMALQAFSFKTKDIEDAMTNTLLYGGDLHSALDWLCLNLSDDALPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDAEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQAPVKIAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIKTENN
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation.  Specifically binds to the 40S ribosome near the mRNA entrance.  Does not possess a processive helicase activity.
What are the official names of this protein?
ATP-dependent RNA helicase DHX29, DEAH box protein 29, Nucleic acid helicase DDXx.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXF_PEA
Sequence: MALNLCTSPKWIGTTVFDSASSSKPSLASSFSTTSFSSSILCSKRVGLQRLSLRRSISVSVRSSLETAGPTVTVGKVTEVNKDTFWPIVNAAGDKTVVLDMFTKWCGPCKVIAPLYEELSQKYLDVVFLKLDCNQDNKSLAKELGIKVVPTFKILKDNKIVKEVTGAKFDDLVAAIDTVRSS
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The F form is known to activate a number of enzymes of the photosynthetic carbon cycle.
What are the official names of this protein?
Thioredoxin F-type, chloroplastic, Trx-F.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant F-type subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KVD28_HUMAN
Sequence: MRLPAQLLGLLMLWVSGSSGDIVMTQSPLSLPVTPGEPASISCRSSQSLLHSNGYNYLDWYLQKPGQSPQLLIYLGSNRASGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQALQTP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 2D-28, Ig kappa chain V-II region FR, Ig kappa chain V-II region GM607, Ig kappa chain V-II region MIL, Ig kappa chain V-II region TEW.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: PVK1_DYSAL
Sequence: QGLIPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR2_OENPA
Sequence: MTRRYWNINLEEMMEAGVHFGHGIKKWNPRMAPYIYANRKGIHITNLTKTARFLAEACDLVFDAASRGRQFLIVGTKKQAAALVARAAIKARCHYVNKKWLGGMLTNWSTTETRLHQFRDLRTEQKTGRLNRLPKRDAAILKRQLSHLQTYLGGIKYMTGLPDIVIILDQQEEYTALRECITLGIPTICLIDTDCDPDLADLPIPANDDAMASIRLILNKLVFAICEGRSSSIRNP
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABZ1_LACLA
Sequence: MTKKYAMTATEVMEVIPNRYPIMFIDYVDEISENKIVATKNVTINEEVFNGHFPGNPTFPGVLILESLAQAGSILILKKEEFQGKMAYIGGIDKAKFRQKVTPGDVMKLEFEITKFRGKVGTADAAAYVDGKKVTTCQFTFIVDEAAEQTN
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity).
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALKMO_MOUSE
Sequence: MRSPGAQDNVSVSQGMRAMFYMMEPSETAFQTVEEVPDYVKKATPFFIFLILLELVISWILKGKPSGRLDDALTSISAGVVSRLPSLFFRSLEVTSYIYIWENYRLLELPWDSTWTWYFTFLGVDFGYYWFHRMAHEINIFWAAHQAHHSSEDYNLSTALRQSVLQQYSSWVFYCPLALFIPPSVFAVHIQFNLLYQFWIHTEIIRTLGPLEVILNTPSHHRVHHGRNRYCIDKNYAGTLIIWDRIFGTFEAENEQVIYGLTHPIGTFEPFNVQFHHLLYIWTTFWTTPGFCHKFSVLFKGPGWGPGKPRLGLSEEIPEVTGQEVPFSSSASQLLKIYTVLQFAVMLAFYEETFANTAVLSQVTLLLRIFFFILTLTSIGFLLDQRSKAATMETFRCLLFLTLHRFGHLKPLIPSLSFAFEIFFSVCIAFWGVRSITQLTSGSWKKP
What is the function of this protein?
Glyceryl-ether monooxygenase that cleaves the O-alkyl bond of ether lipids.  Ether lipids are essential components of brain membranes (By similarity).
What are the official names of this protein?
Alkylglycerol monooxygenase, Transmembrane protein 195.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family. TMEM195 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RSMH_FRAAA
Sequence: MHTPVLTDRVLELLAPALSRPGAVVVDATVGLGGHAAALLAAFPEVRVVGLDRDLDALAHSGERLRALAPERVRLVHAVYDEIGTVLAGLGSARVQGVLFDLGVSSLQLDTDARGFAYSRDAPLDMRMDATRGLTAAEVLNTYDAAALARILRDYGEERFARRIAESVVRARAVEPFTTSARLVDLVRDAIPAPARRTGGNPAKRTFQALRIEVNSELDVLARALPAAFDALAVGGRLVVLSYHSLEDRLVKRELRGYAETLVPPDMPVVPAGAEPRLRWLTRGAEPAGEVEKADNPRAASVRLRAAERTAPNPDRTQPTIGGAS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TARI_LACPL
Sequence: MIYAQILAGGKGTRMGNVPMPKQFLLLADKPILIHTIEKFTLESRFDAILVVCPADWVSHTEDIIKKYITDERVHVVVGGADRNETLMSGINYIQDHYGIQDDDVVVTHDAVRPFITQRIINDNIVAVLENKAVDTVVPAIDTIVRGANDQVTDIPVRSEMYQGQTPQSFHIKILIDSYNALSSEQKASLSDSCKICSLAGQKVSLVRGENYNFKITTPFDLRVASALVEKRS
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: KHSE_BURO1
Sequence: MAVFTAVSDSDLAQWMRHYELGDVLAFRGIPSGIENSNFFLTTTRGEYVLTIFEKLTAQQLPFYLDLMRHLAAHGVPVPDPIPRDDGALFGELHGKPAAIVTKLDGAAELAPGVEHCIEVGQMLARLHLAGRDYPRNQPNLRSLPWWQENVPAIVPFITDAQRALLEGELAHQAGFFASDDYAALPAGPCHCDLFRDNVLFAHAAPGTGHDVRLGGFFDFYFAGCDKWLFDVAVTVNDWCVDLATGVLDVARADALLRAYQTVRPFTAEERRHWSDMLRAGAYRFWVSRLYDFYLPRAAEMLKPHDPGHFERILRERIAHTPALPEIQTACN
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RISB_ENT38
Sequence: MNIIEAAVATPDARVAITIARFNNFINDSLLDGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQEAEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: REG6_PYRHO
Sequence: MRVPLDEIDKKIIKILQNDGKAPLREISKITGLAESTIHERIRKLRESGVIKKFTAIIDPEALGYSMLAFILVKVKAGKYSEVASNLAKYPEIVEVYETTGDYDMVVKIRTKNSEELNNFLDLIGSIPGVEGTHTMIVLKTHKETTELPIK
What is the function of this protein?
DNA-binding protein involved in the repression of transcription of a large number of genes, thereby arresting growth, in response to environmental changes (PubMed:14976242, PubMed:18073105).  Binding sites are identified in promoters of approximately 200 transcription units, including genes involved in ATP synthesis, transmembrane transport, translation and DNA synthesis (PubMed:18073105).
What are the official names of this protein?
HTH-type transcriptional regulator FL11, Feast/famine regulatory protein FL11, FFRP FL11.
Protein: GREA_NEIMA
Sequence: MQKIPLTVRGAELLKQELQQLKSVARPEVIEAIAEARSHGDLSENAEYEAAKERQGFIEGRISELEHKLSVAHIINPTEIHAEGKIVFGTTVTLEDLETEEHVTYQIVGEDEADIKQGKIYVGSPIARALIGKEEGDTAEVQAPGGVREYDIIEVRYI
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: CH601_RENSM
Sequence: MAKIIAFDEEARRGLERGLNILADAVKVTLGPRGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDEVAGDGTTTATVLAQALVREGLRNVAAGADPLSLKRGIEKAVAAVTEQLLASAKEVETKEEIAATASISAADTQIGALIAEALDKVGKEGVITVEESNTFGLELELTEGMRFDKGYISQYFVTDAERQETVLEDPYILIVSSKISNVKDMVGILEKVMQSSKSLLIIAEDVETEALATLIVNKVRGLFKSVAVKAPGFGDRRKAQLADIAILTGGQVISEEVGLSLENATVDLLGQARKVVVTKDETTIVEGAGDAEQIAGRVAQIRAEIENTDSDYDREKLQERLAKLAGGVAVIKAGSATEVELKERKHRIEDAVRNAKAAVEEGIVPGGGVALIQAGVKAFETLQLEGDEATGANIVKVAIDAPLKQIAINAGLEPGVVVDKVRGLPVGHGLNAATGVYEDLLAAGVNDPVKVTRSALQNAASIAGLFLTTEVVVADKPQKNVPAAPGGDEMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KANL3_HUMAN
Sequence: MAHRGGERDFQTSARRMGTSLLFQLSVHERELDLVFLDHSYAKPWSAHPDASSARPTRMLFVTPRRQHESTIESDVPIDVETVTSTPMPLYDNQKARSVMNECERHVIFARTDADAPPPPEDWEEHVNRTGWTMAQNKLFNKILKALQSDRLARLANEGACNEPVLRRVAVDKCARRVRQALASVSWDTKLIQWLHTTLVETLSLPMLAAYLDALQTLKGKIPTLIDRMLVSSNTKTGAAGAEALSLLLKRPWDPAVGVLSHNKPSKLPGSPLILIASSGPSSSVFPTSRRHRFWQSQLSCLGKVIPVATHLLNNGSGVGVLQCLEHMIGAVRSKVLEIHSHFPHKPIILIGWNTGALVACHVSVMEYVTAVVCLGFPLLTVDGPRGDVDDPLLDMKTPVLFVIGQNSLQCHPEAMEDFREKIRAENSLVVVGGADDNLRISKAKKKSEGLTQSMVDRCIQDEIVDFLTGVLTRAEGHMGSEPRDQDAEKKKKPRDVARRDLAFEVPERGSRPASPAAKLPASPSGSEDLSSVSSSPTSSPKTKVTTVTSAQKSSQIGSSQLLKRHVQRTEAVLTHKQAQAQFAAFLKQNMLVRKALPPGTSSCLFVPISSEPPEEGEKEDLRVQLKRHHPSSPLPGSKTSKRPKIKVSLISQGDTAGGPCAPSQGSAPEAAGGKPITMTLGQASAGAKELTGLLTTAKSSSSEGGVSASPVPSVVSSSTAPSALHTLQSRLVATSPGSSLPGATSASSLLQGLSFSLQDISSKTSGLPANPSPGPAPQATSVKLPTPMQSLGAITTGTSTIVRTIPVATTLSSLGATPGGKPTAIHQLLTNGGLAKLASSLPGLAQISNQASGLKVPTTITLTLRGQPSRITTLSPMGSGAAPSEESSSQVLPSSSQRLPPAP
What is the function of this protein?
As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
What are the official names of this protein?
KAT8 regulatory NSL complex subunit 3, NSL complex protein NSL3, Non-specific lethal 3 homolog, Serum inhibited-related protein, Testis development protein PRTD.
Protein: CARA_BACCZ
Sequence: MKRQLILEDGTVLIGTGFGGEIEKSGEVVFTTGMTGYQETLSDPSYCGQIVTFTYPLIGNYGINRDDFESIHPSVNGLIVNEICDHPSNFRNEISLNDYLKERKIPGLAGIDTRKLTRKIRQYGTLRGRLCNMDADVEYIVSQLKATVFTDHVKRVSTKDPYPSPGRGHRVVLVDFGMKHGILRELNKRDCDVIVVPYNTTAEEILRLSPDGIMLSNGPGDPKDVPEAIEMLKDIIGKVPLFGICLGHQLFALASGANTSKLKFGHRGLNHPVKNIATGKVAITSQNHGYAVEEESVENTELEITHVALNDGTVEGLRHKKFPAFTVQYHPEASAGPEDANDLFEDFLTMIENFKKEGEELCQNA
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: ALYP_PSESO
Sequence: MPGDKVIMKSGEWKSQFIHFKGKGTAEKPITLTAETKGSVLLTGNSNLKIDGEWLVVDGLSFKNGFSLKDDVVVFTKTTTNSRLTNTSIENYNPVDKTLDYKWVSLYGHHNRVDHCSITGKNHQGTTLVVWLDDKPNYHQIDHNYFGPRPELGANGGETIRIGTSAFSMNDSYRTVQNNIFDKCDGEVEIISIKSGFNKILNNLFYECAGTVTFRHGNNSEVSNNYFIANNVTNSGGVRIIGENQKVYGNYLYKVAGRTLRSAISVMNAYEKPALNDYWQVKNADIQNNIIVGAREAFVLGSGKDNDRTLAPDGVNISNNYIINPTTLLVTQDEPKNLKMQNNQVEGASIVTGFVKMGNDLQMSDGIWQKKTEIKKPFWLATAIGPEWKKDHRSFIFK
What are the official names of this protein?
Alginate lyase, Poly(beta-D-mannuronate) lyase, Poly(mana) alginate lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 6 family.
Protein: SAHH_NITEU
Sequence: MSATINPVVDNSVFTDCKVADLSLADWGRKEIAIAETEMPGLMALREQYADKKPLAGARIAGSLHMTIQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIAARNIPVFAYKGESLEEYWDYAHQIFEWASDGSHTANMILDDGGDATLLLILGSKAERDPSVIANPTNEEEQVLFASIRSRLASHPGWYSRNLAAIRGVTEETTTGVHRLYEMEKKGELPFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVCGYGDVGKGCAQSLRGLGATVWITEIDPICALQAAMEGYRVVTMDDACDKADIFVTATGNLRVITHDHMLKMKDQSIICNIGHFDSEIDIASVQKYQWENIKPQVDHVIFPTGRRIIVLAQGRLVNLGCATGHPSFVMSSSFTNQVLAQIELWQNGKDYQKKVYVLPKRLDEMVARLHLGKLGVKLTELTDEQAHYLNLDKNGPYKPEMYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_CLOB6
Sequence: MNIKPEEITSIIRQQIENFNTNIETIDSGTIIQIGDGIARVYGLEDCMEGELIEFPNDVYGMALNLEQDNVGCVLLGSEEGIKEGNVVKRTKKVVEVPVGEALVGRVVNSLGMPIDGKGPVLTTETRDVEVPAPGVIDRQSVKEPLQTGIKAIDSMIPIGKGQRELIIGDRQTGKTAIAMDTILNQKGKDVICIYVAIGQKQSTVAHIVNDLTKMGAMDYTIVVSSTASDSAPLQYLAPYAGCSMGEYFMHKGKDVLIVYDDLSKHAVAYRTMSLLLRRPPGREAYPGDVFYLHSRLLERSARLSEKLGGGSLTALPIVETLAGDVTAYIPTNVISITDGQIFLESELFNAGQRPAVNAGISVSRVGGNAQIKAMKQVAGTLRLELAQYRELAAFSQFGSDLDKESVKRLEKGKRLVEILKQPQYSPMPVEKEIIILYAAVSNHLIDIPVNKIKEFEKELFNYIDTHYRDIGKDILEHKQLTDELKSKLDKAINDFKNVFLSEI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PDXT_METPE
Sequence: MDVKIGVLALQGDVAEHITAFQQVLDTIPSVVGSVVEVREAAQIPSLDAIAIPGGESTTISRLIEKNRMHEVLTGFQGGIFATCAGMVLMAKSVEDPRICPLGLIDMEVDRNAFGRQRESFEADIPVQGLDAPFHAVFIRAPVVRSVGAEATVLATIDQGIVAVLQGKHMALSFHPELAGDLRLHRLFLTGLGIV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.