PharMolix/UniProtQA huggingface dataset:
Protein: Y1106_METJA
Sequence: MLKNLLYKIEKLRSGELEGFEVLKEHIQSLDEFQYQQIVERLKFQIELVEKYKPKVRPAIDPMVSTELGIYRRLDDFEIGKLLDYPECCIKSFVEDVRVAIDREHLKEVEEMKEELKNKGIYAIVLPSGFIPCSLKCEEAIKRGFIGYLTKEEFDKILELEKELKEKIRHWHFGYDEYYEKIILP
What are the official names of this protein?
Uncharacterized protein MJ1106.
What is the protein family that this protein belongs to?
To M.thermoautotrophicum MTH236.
Protein: SHF_MOUSE
Sequence: MEPYEAQKMMAEIRGSKETAAQPLPLYDTPYEPEDEGASPEGEGTPWPRESRLPEDDERPPEEYDQPWEWKKERISKAFAAQFEGSENCLSPGREEKGRLPPRLSAGNPKSAKPLGMEPSSPLGEWTDPALPLENQVWYHGAISRTDAENLLRLCKEASYLVRNSETSKNDFSLSLKSSQGFMHMKLSRTKEHKYVLGQNSPPFSSVPEIVHHYASRKLPIKGAEHMSLLYPVAIRTL
What is the function of this protein?
Adapter protein which may play a role in the regulation of apoptosis in response to PDGF.
What are the official names of this protein?
SH2 domain-containing adapter protein F.
Protein: RLMH_LACPL
Sequence: MNIKIICVGKLKEKYFKQGIAEYAKRMSKFAKFQIVEVPDEKAPESLSNAEMENVKAKEGQRILEKIKDRDYVYALAILGKERSSEEFAAEIDKLTTYGHSDIDFVIGGSLGLSPEVLKRADTQISFGRFTLPHQLMRLVLSEQVYRAFMINVGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCD_METS5
Sequence: MKAAVLHTYKEPLSIEDVNISQPKAGEVKIKVKATGLCHSDVNVFEGKTPVPPPVVAGHEISGIVEEVGPGVTRVKPGDRVISAFIHPCGKCGNCVAGKENLCETFSQVRLKGVMPDGTSRLSKDGKEIRTFLGGGFAEYAIVGENALTRVPEDMDLEKVAVLGCAGLTGYGAISSSKIEPGDTVAVIGVGGVGLSTIQLLRASGAGRIIAVGTKKWKLDRAMELGATDVVNSKEIDPVKAIKEITGGGPQVVIEAGGNEDTIHMALDSVRIGGKVVLVGLPPATAMIPIRVASIVRGGIEVVGNYGGRPRVDMPKLLELVRQGRYDPSRLVTGRFRLEEINEAVKMLEEGEAIRSLIIP
What is the function of this protein?
Catalyzes the reduction of succinate semialdehyde to succinyl-CoA.  The enzyme is specific for succinate semialdehyde and succinyl-CoA, and only shows low activity with palmitoyl-CoA.  There is no activity with NAD(+) as cosubstrate.  Participates in the 3-hydroxypropanoate/4-hydroxybutyrate cycle, an autotrophic CO(2) fixation pathway found in some thermoacidophilic archaea.
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase (acetylating).
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: PANC_LISMF
Sequence: MLIIRNKQDLKEAILEQKKANKTIGYVPTMGFLHEGHMTLVSHARKETDFVVMSVFVNPTQFGPNEDFDAYPRDEAHDAKLAEEGGVDILFVPTVEEIYPTELATKLHVIKRVSVLDGADREGHFDGVVTVLTKLFHLVNPDNAYFGQKDAQQVAVVSGLVEDYFFPINLRIIATVREADGLAKSSRNVYLTEKERKEAPVIHEALQLGRELIESGETNEAKIVQVMTDKINEQPSHENIAYLALYSYPEFTPVTDWTKGIIIAAAVKYSKARLIDNELINVKRR
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YONU_BACSU
Sequence: MEKKFLDAIQQLTKELEMLKKDIDSIKEATVRIDKDLLEYREEISKVKQDDSVLIMQQHKDN
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YonU.
Protein: EZRA_LISMO
Sequence: MYYMLIGFIIVVIAVIGAGYILKRKHYQRINELEEKKIKLRERPVIDELSKVKKLKLTGQTEALFESWRSSWDEIETRLFPDLEEVLLEAEMNTDRYKFRSATHAENDIEQMLVVIEKQMDQILGGLKELLISEEKNAKESRATKEKFAELRREVLTRGFKLGETLPYIETKLSELSESLNSYDSLTDQGDHLEAREIVIVVQKEMQVIEAQMERIPSLLHETDTILPEEMTKLRAGYEEMVRKGYYLAQMELDKEISRMKNQIDKMKKNVINLDLDEAEQGVEELHNEIDLFYDTLEHEAEARHFVKENHSPTSDKLQRQNAVSDALAEQITEVKQTYHVAEDDLAVYLKTSAKLSEAKENFEQLTALIASGEIAYSAAQDTLKEIDAALITISTEQDKFAEELRSLRKDELEARDDAERMRRAIITLDRKMERERLPGLPEEYLSLREHMGESIDALEKRLEEKPLNMKAVSQDWRIAEEDLTHLTEKAEEMMENVRLVEHVIQYANRYRLRNKELADELVQAENHFYNDYQYKKALEIAVTALEKVETGAFKKVEKAYESKVSVDDIE
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: LPE10_CANGA
Sequence: MLLVNRAITLNLVKRCCWRSTMFMTPKRFLGTSEEESTAALLLQKNLIQRNNMLYGHGSGTIRCTVFDAGGNIVSPALDIKREELVAKHGLLPRDLRKIEKSRKNDLVPSFLVRKNGILVSLATIKTLIKPDMVIVFDSFGSLNSTSHKAFLNSLKLRLQNLDMVELKKDPLPYEFRALESIFISALSNLTSEMNVQVTICKGILQDLEYSITRDKLKFLLGQNKKLSNFYKKTVLIRDMLDDLLEQSDVLCSMYLSDLKNGVEHKDDDHSEIEMLLETYHNHLDEIVQITENIISNVKTTEEIINIILDSNRNQLMLLGIRFSIGMLSLGGPIFIGSLYGMNLENFIEETDYGFIAASAIGMISLGALYFYSIKHLHKLQKMSLFNYTNYARDVKK
What is the function of this protein?
Mitochondrial inner membrane magnesium transporter required for mitochondrial magnesium homeostasis.  Modulates the conductance of the MRS2 channel.  Involved in the splicing of mRNA group II introns in mitochondria by affecting mitochondrial magnesium concentrations, which are critical for group II intron splicing.
What are the official names of this protein?
Mitochondrial inner membrane magnesium transporter LPE10.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LEXA_PASMU
Sequence: MKPFKALTARQQEVYDLLKRHLENTGMPPTRAEISKELGFRSPNAAEEHLKALARKGVIEIISGTSRGIRLLLEESESDENQGLPLVGRVAAGEPILAEQHIEGTYQVDANMFKPQANFLLKVYGQSMKNIGILDGDLLAVHSTKDVRNGQIVVARIEDEVTVKRLERKGSVIYLHAENEEFAPIVVDLNQQPNFEIEGIAVGIIRNNAWM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: RS21_BACMK
Sequence: MSKTVVRKNESLEDALRRFKRSVSKTGTLAEARKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: IF6_BABBO
Sequence: MAIRTQYENSNEVGVFATLTNSYALVSLGSSCNFASVFEAELMPQIPVVQTTIGGTRVVGSVTVGNRKGLLVSSICTDTELRHLRNSLPDSVEIRRIDDRLSALGNVITCNDYVGLIHVDIDRETEEIVEDVLGIEVFRASIAGNVLIGSYCRFQNKGGLVHVKTTTDEMEELSQLLQIPLTSGTVNRGSDVIGGGLIANDWVAFCGMSTTATEIATIERIFQLSRPKEFDPSVSNSHTLRNALIDTLI
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  May also be involved in ribosome biogenesis.
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: ENG1_THEFY
Sequence: MSHASRRRWRRATTSAATAALLCGALLTFPSAPAAAQVRLGSGSYTTVLPPGASGPSDHTGAPVAPKVTADFTQPVVTNDWWSSLIFQRYPGNPYGENLYAHPLSFKAQAHGLEVGYPDTPELVADGLKYQYTHSPDFVLGIHGLNAPAAKVAGYSDWTVTADLSDGTRQLRTTIGQGLPFVYADVSGGPIRVEFTAPPTVWRRSGNAVGVTVNGHHYALFAPSGTTWSESDTVFTADVGGSGYASVALLPSPDDFDRYAPYAYSFVTSTTLTYDYDPASATLTSTYRVTTEAREGTAQGTLLALYPHQWKETTTALTDLSYASPRGPMRVVEGDRFTTELTTHGILPSLPTVDSADHQRLRALIDAELHASDPWKGASDTYWTGKALGRLAQLVPIADSIGYTAGRDALLDLLKNKMEDWLTADGPGDNAQFYYDDQWDTLIGFPASFGSNTELNDHDFHYGYFITAAATIARYDRSWISEERWGPMVTTVLRDANNPDRDDERFPWLRSFSPYAGHGWASGHAGFASGNNQESSSEAMHFAASAALLGSLIGDEELRDLGVYLHTTQASAMRRYWQNADGDAFPAGYSHDVVGMVWSDGGDHRIWWDGTPEELYGINYLPITAGSLYLGHDPEHAAAMHQSLVTRLGRQPQVWRDIHWAHQALSDPDAALAAFEAQWQSYEPESGSSKAHTYQWLSTLAEFGTVDTSVTADTPHYAVFRDGDRRTYVAFNPTGQPLTVTFSDGTTLTVPPGQLATG
What is the function of this protein?
Cleaves internal linkages in 1,3-beta-glucan (PubMed:17115704, PubMed:19435780).  May contribute to biomass degradation by hydrolyzing the 1,3-beta-linked plant polymer callose that is present in decomposing plant tissue (PubMed:17115704).
What are the official names of this protein?
Glucan endo-1,3-beta-D-glucosidase, Endo-1,3-beta-glucanase, Laminarinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 81 family.
Protein: ATG8_CANAL
Sequence: MRSQFKDEHPFEKRQAEAARIAQRFKDRVPVICEKVENSDIPEIDKRKYLVPVDLTVGQFVYVIRKRIKLPSEKAIFIFVNDILPPTAALISTIYEEHKDEDGFLYVLYSGENTFGEKLAIDISSLDFSDIPDYV
What is the function of this protein?
Ubiquitin-like modifier involved in autophagosomes formation.  With ATG4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Participates also in membrane fusion events that take place in the early secretory pathway.  Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress.  The ATG8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy.
What are the official names of this protein?
Autophagy-related protein 8, Autophagy-related ubiquitin-like modifier ATG8.
What is the protein family that this protein belongs to?
Belongs to the ATG8 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Vacuole membrane; Lipid-anchor.
Protein: MURG_ERWT9
Sequence: MSGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIDIEFIRISGLRGKGIKALLAAPLRIFNAWRQARAIMKAWQPDVVLGMGGYVSGPGGLAAWSCGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPDAEVVGNPVRTDVLALPLPSVRLSGRDGPTRVLAIGGSQGARVLNQTMPQVAARLGDSISLWHQVGKGALDEVNADYTRVNQSQHRVSEFIDDMASAYAWADVVVCRSGALTVSEVAAAGLPAIFVPFQHKDRQQYWNALPLEQAGAAVIYEQPQFTADAVAATLAGWDRPTLLAMAEKARAVAIPDATERVAAEVSKAAR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YEEX_SALAR
Sequence: METTKPSFQDVLEFVRLFRRKNKLQREIQDIEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKSDYEDRVDDYIIKNAEISKERRDISKKLKAMGEMKHADVKAE
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: YH046_YEAST
Sequence: MNAENRNIAFNCQVSYFLAISSDLRIINDFVPFNLSFISSLGDESSSIFSSTISSLQFFSVFLRFVWLERLSSGTSIIFPLAQRVTTVFGAQVERTQAKFFYQDLMSL
What are the official names of this protein?
Putative uncharacterized protein YHL046W-A.
Protein: CNR4_MAIZE
Sequence: MSTYPPPTGEWTTGLCGCFSDCKSCCLSFLCPCIPFGQVAEVLDKGMTSCGLAGLLYCLLLHAGVAVVPCHCIYTCTYRRKLRAAYDLPPEPCADCCVHMWCGPCAISQMYRELKNRGADPAMGRQPAFSLSLTSHCRFFLKSKYYHIIKKNWRTVKYG
What are the official names of this protein?
Cell number regulator 4, ZmCNR04.
What is the protein family that this protein belongs to?
Belongs to the cornifelin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRE_CRYNJ
Sequence: MSSQALDSAKVAFIEAAIEHGVLLFGNFTLKSGRQSPYFFNAGLLYSSSLLSTTAQAYAKVLSSSRIPDFDVLFGPAYKGISLAAVSAVSLYQQTGKDIGYCYNRKEKKDHGEGGTMVGAPLKGRIVIIDDVLTSGKAIREAIDILKASPEAKLVGIVQLVDRQEKGQSGSGKSTVQEVEEEFGVPVEPIIGLDDIVKYLESSGKWEKELQEVRKYRAEYGVQRS
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: Y5528_MYCVP
Sequence: MQPGGQPDMSALLAQAQQVQQQLMEAQEALANAEVNGQAGGGLVQVTMRGSGEVVAVRIDPKVVDPSDVETLQDLIVGAVADAAKQVTILAHDRLGPLAGGMGGLGLPGM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Mvan_5528.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TYSY_PSYWF
Sequence: MITSKNEAAYLDLIRYVRDHGTEKGDRTGTGTRSHFGAQLRFDLKDGFPLLTTKKVHMKSITYELFWFLKGDTHVKYLQDHGVRIWNEWSTAEQTARFGRPEGELGPIYGHQWRNYGATKAEDGRYNQDGVDQVVEVIEQIKSNPNSRRLIVSGWNPAEATQVALPPCHTLFQFFVADGKLSCQLYQRSADLFLGVPFNIASYSLLTHMIAQVCDLEVGEFIWTGGDCHLYQNHIDQVNEQLSREAYELPKLWLNPEIKDIFDFTFDDIRVEGYQSHPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_ECOLI
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4) (Probable).
What are the official names of this protein?
Probable glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BM2_INBYA
Sequence: MLEPFQILSICSFILSALHFMGWTIGHLNQIKRGVNLKIRIRNPNKETINREVSILRHSYQKEIQAKETIKEVLSDNMERLSDHIVIEGLSAEEIIKMGETVLEVEELH
What is the function of this protein?
Forms presumably a highly low-pH gated proton-selective channel.  Trp-23 may function as a minimalistic gate that opens and closes the pore.  When the environmental pH is lower than a threshold, the BM2 channel would be activated and selectively transport protons across the membrane from the extracellular side to the cytoplasmic side.  Crucial for the uncoating process.  When the virion is internalized into the endosome, the channel acidifies the virion's interior, promoting the dissociation of matrix protein 1 (M1) from the ribonucleoprotein (RNP) thus allowing the transport of the RNP from the virion into the cell's nucleus.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation (By similarity).  Plays a crucial role in virion assembly.  Expressed in the late phase of the infection.
What are the official names of this protein?
Matrix protein 2, BM2.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type III membrane protein. Host cell membrane; Single-pass type III membrane protein. Note=Transported to the plasma membrane through the trans Golgi network.
Protein: TBX5_HUMAN
Sequence: MADADEGFGLAHTPLEPDAKDLPCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPFSSESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTTDHPYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPGTLQPPEFLYSHGVPRTLSPHQYHSVHGVGMVPEWSDNS
What is the function of this protein?
DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation (PubMed:25725155, PubMed:25963046, PubMed:29174768, PubMed:26917986, PubMed:27035640, PubMed:8988164).  Binds to the core DNA motif of NPPA promoter (PubMed:26926761).
What are the official names of this protein?
T-box transcription factor TBX5, T-box protein 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Acetylation at Lys-339 promotes nuclear retention.
Protein: EFEO_YERPN
Sequence: MSIWFFRRTALHAALLSLPVFAISAQAADIQQVKITVNDKQCEPMALTVPAGKTQFIVHNVSQKGLEWEILKGVMVVEERENIAPGFTQKMTANLEPGEYDMTCGLLSNPKGKLTVTVAAGEQAPVKPDAMALVGPIAEYKVYVTQEVAQLVSQTKAFTDAVKAGDLALARKLYAPTRQHYERIEPIAELFSDLDGSIDAREDDFEQKSADPKFTGFHRLEKILFGDNTTKGADKFADLLYQDTLELQKRIAGLTFAPNKVVGGAAGLIEEVAASKISGEEDRYSRTDLWDFQANVDGAQKIVNLLRPLLEKADKPLLQKIDANFNTVDSVLAKYRTKEGYESYEKLTDADRNAMKGPITALAEDLAQLRGVLGLD
What is the function of this protein?
Involved in Fe(2+) uptake.  Could be an iron-binding and/or electron-transfer component (By similarity).
What are the official names of this protein?
Iron uptake system component EfeO.
What is the protein family that this protein belongs to?
Belongs to the EfeM/EfeO family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TRMB_FRAP2
Sequence: MSDNSKENLRQIKSYVQRAGRVTKKQQQALDDYASKYMIEYDQNKSLDFSEIFKNSNDVVLEIGFGMGGSLVQMALENPTKNYLGIEVHKAGVGNILYEIEHQNISNLLVMSHDAVEILENMISDNSLSGMQIYFPDPWHKKKHNKRRLVNQSNVDLFAKKLKVGGVFHYASDWLPYAEEVLELLENDNKYKNLYDGFAPRPEWRPLTKFEKRGQNLDHPISDILFEKI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: NUOH_CHLPD
Sequence: MSVMALSQIRIPLLMGNSLNAWSEALTGFSIWGFPLGLVILAAIPLVFIALYALTYGVYGERKISAFMQDRLGPMEVGKWGILQTLADILKLLQKEDIVPAAADKFLFVVGPGILFVGSFLAFAVLPFSSAFIGANLNVGLFYAIGIVSIEVVGILAAGWGSNNKWSLYGAVRSVAQIVSYEIPAGIALLCGAMMAGTLDMQQITMLQSGHLGFAHFNLFQSPIAWLPFLIYFIASLAEVNRAPFDIPEAESELVAGYFTEYSGMKFAVIFLAEYGSMFMVSAVLSIVFLGGWNSPLPDLGPVSLNAMTSGPVWGVFWIISKGFFFIFVQMWLRWTLPRLRVDQLMYLCWKVLTPFAFIGFVLTAIWEIYVP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TPIS_PSEPF
Sequence: MRRPMVAGNWKMHGTRASVAELINGLRHLALPSGVDVAVFPPCLYINQVIDGLKGKSISVGAQNSAVESMQGALTGEIAPSQLVDAGCSLVLVGHSERRQIMGERDGMLNRKFAAAQACGLIPVLCVGETLEQREAGKTLEVVGRQLGSIIEELGVGAFANAVIAYEPVWAIGTGLTATPQQAQDVHKAIREQLAAENSEVARGVRLLYGGSVKAANAVELFGMPDIDGGLIGGASLNADEFGAICRAAGN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUA_SERMA
Sequence: MLAVELVIVLLAIFLGARLGGIGIGFAGGLGVLALALIGVKPGNIPFDVISIIMAVIAAISAMQVAGGMDYLVQQTEKLLRKNPKHITILAPIVTYFLTIFAGTGNISLSALPVIAEVAKEQGIKPCRPLST
What is the function of this protein?
Responsible for the transport of C4-dicarboxylates during aerobic and anaerobic growth.  Required for the uptake of L-aspartate as a nitrogen source during aerobic growth.  The uptake of L-aspartate in aerobic conditions is coupled to the excretion of fumarate, resulting in the net uptake of nitrogen without carbon uptake.  In addition, during anaerobic growth, catalyzes the uptake of fumarate, malate or aspartate coupled to the export of succinate.  May play a a general role in anaerobic C4-dicarboxylate transport.
What are the official names of this protein?
C4-dicarboxylate transporter DcuA.
What is the protein family that this protein belongs to?
Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TKN1_PSEGU
Sequence: QPHPDEFVGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Kassinin-like peptide K-I, PG-KI.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNB_BUCAI
Sequence: MFQNNPLLTQLKKNLHAKSPRVEGIVKSTERGFGFLEVDPQKSYFIPPKNMKNVMHGDKIIALLTTEKDREIVEPEKLIEPFLNRFVGKIEKKDNRLFIVPDYPFLKDLITCQPNKNCINIFQNGDWAVAQLKKHKLKGDHLFYAELTEKITQEDDPLIPWWVTLARHDLDRKEPLAEDDDLILKESDNRKDLTDLDFITIDNTNTKDIDDALFVSEKNNGDISLIVAIADPTAYIKHGSKLDVIASKRIFTNYLPGFNIPMLPRNLSEDICSLNPNKRRPVLACHITVLKNGNISNKIEFFLAWIKSKSKLSYDHVSDWIEKIGSWIPPTKSIANQILILHRLCLLRIKWRKKNAVLFKDSIEYRFHVSEHGKIIDVLIEKRRIAHKIIEESMIVANISAANFLSKNIGFGIYNVHSGFDLVNAENAVSFLRSYNLNFTVKEITTLKGFCNLRRVLNIISNNYIDSRIRRFQSFGDFSTIPGPHFALGFSEYATWTSPIRKYSDMINHRLLKSIIKKEKSIKPGEDIKIKISEQRRRNRMAERDVLDWLYTIFLQKKKYQNQKFNAEITDISRSGIRARLIENGANVFIPGTLIHPIREELNFNQESGKVFINGIMHYKISDLIQVTLSDIRLKTRSIIAKPVFEKFK
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity).
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.