PharMolix/UniProtQA huggingface dataset:
Protein: NUOA_RALSO
Sequence: MNLEAYFPVLLFIIIGVGLGLALMTIGRILGPNNPDPDKLSPYECGFEAFEDARMKFDVRYYLIAILFILFDLETAFLFPWGVALRDIGWPGFFAMGVFLLEFLVGFVYIWKKGALDWE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KA17C_MESMA
Sequence: QRQCQNVQNCYKYCMSPKKCEYGTCYCEPSP
What is the function of this protein?
Blocker of potassium channels (Kv).
What are the official names of this protein?
Toxin BmKK12.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 17 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOC_HERA2
Sequence: MIDRATLEQRVSAQFPTVRIGDESGDLCLTVERQQLPALAGWLRDEPDLAFTFLNQLCGVDYLGRDPRFEVVVHLTSFQNKMRVTLHIEVPEADPTIPTLARLFPTANFQERETYDMFGIIFTGHPGLERILMPEDWLGHPQRKDHPLGYEEVAFTHNEDWIYANKPFAKE
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS7_LIMRJ
Sequence: MPRKGHVQKREILPDPMYNSKLVTSLIDHLMIDGKRGTATKILYAAFDEIKNETGNDPVEVFQQAMENVMPVLEVKARRVGGSNYQVPIEVRPDRRTTLGLRWIVQYARLRGEHTMVERLAREIIDASNNTGASVKKREDTHRMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: YDJH_ECOLI
Sequence: MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDAINEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLVTEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEIFTQAKARQMIICADMIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLACGVKTVVIKTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNLRECARFANATAAISVLSVGATTGVKNRKLVEQLLEEYEG
What are the official names of this protein?
Uncharacterized sugar kinase YdjH.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: EX7L_STRR6
Sequence: MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYFSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKVEPDGVGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPNE8_MOUSE
Sequence: MWARDKCSVPQLEMDSRYTSATGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI
What is the function of this protein?
Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.
What are the official names of this protein?
Copine-8, Copine VIII.
What is the protein family that this protein belongs to?
Belongs to the copine family.
Protein: SDK2_HUMAN
Sequence: MWGLLIWTLLALHQIRAARAQDDVSPYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEFKWLHNNRELTKFSLEYRYMITSLDRTHAGFYRCIVRNRMGALLQRQTEVQVAYMGSFEEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDGRKIPPSSRIAITLENTLVILSTVAPDAGRYYVQAVNDKNGDNKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGISDHNRRLTIPNPTGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTPSSPSQSVPAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALGHSEMMSLDESSFPALELNNRRLSVKNSFCRKNGLYTRSPPRPSPGSLHYSDEDVTKYNDLIPAESSSLTEKPSEISDSQGSDSEYEVDSNHQKAHSFVNHYISDPTYYNSWRRQQKGISRAQAYSYTESDSGEPDHTTVTNSTSTQQGSLFRPKASRTPTPQNPPNPPSQQSTLYRPPSSLAPGSRAPIAGFSSFV
What is the function of this protein?
Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion.  Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs and the excitatory amacrine cells VG3-ACs.  Formation of synapses between these two cells plays a key role in detection of motion.  Promotes synaptic connectivity via homophilic interactions.
What are the official names of this protein?
Protein sidekick-2.
What is the protein family that this protein belongs to?
Belongs to the sidekick family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Synapse.
Protein: ACPS_MYCMS
Sequence: MINNVGIDIVENKRIKLKKEFIIKVLSTNEIQTFNTKTKKQKKEFLAGRWAVKEAIIKTLDQAISMNKIDIEYVNQKPVIQNKELQNILISISHEKKYAIGIALKQSDNK
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_AQUAE
Sequence: MRVKGPSSRRKKKKILKLAKGYRGQRSRSYRRAKEAVMRALYYQYRDRKLRKREFRRLWIARINAAVRAYGLNYSTFINGLKKAGIELDRKILADMAVRDPQAFEQVVNKVKEALQVQ
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ACTN2_BOVIN
Sequence: MNQIEPGVQYNYVYEDDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERVEHLAEKFRQKASTHETWAYGKEQILLQKDYESSTLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTVDEIRSKWDKVKQLVPIRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPAYSGPGSVPGALDYTAFSSALYGESDL
What is the function of this protein?
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures.  This is a bundling protein (By similarity).
What are the official names of this protein?
Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein.
What is the protein family that this protein belongs to?
Belongs to the alpha-actinin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle.
Protein: SENP2_PONAB
Sequence: MYRWLVRILGTIFRFCDRSVPPARALLKRRRSDSTLFSTVDTDEIPAKRPRLDCFIHQVKNSLYNAASLFGFPFQLTTKPMVTSACNGTRNVAPSGEVFSNPSSCELTGSGSWNNMLKLGNKSPNGISDYPKIRVTVTRDQPRRVLPSFGFTLNSEGYNRRPGGRRHSKGNPESSLMWKPQEQAVTEMISEESGKGLRRPHRTVEEGVQKEEREKYRKLLERLKESGHGNSVCPVTSNYHSSQRSQMDTLKTKGWGEEQNHGVKTTQFVPKQYRLVETRGPLCSLRSEKRCSKGKITDTEKMVGIRFENESRRGYQLEPDLSEEVSARLRLGSGSNGLLRRKVSIIETKEKNCSGKERDRRTDDLLELTEDMEKEISNALGHGPQDEILSSAFKLRITRGDIQTLKNYHWLNDEVINFYMNLLVERNKKQGYPALHVFSTFFYPKLKSGGYQAVKRWTKGVNLFEQEIILVPIHRKVHWSLVVIDLRKKCLKYLDSMGQKGHRICEILLQYLQDESKTKRNIDLNLLEWTHYSMKPHEIPQQLNGSDCGMFTCKYADYISRDKPITFTQHQMPLFRKKMVWEILHQQLL
What is the function of this protein?
Protease that catalyzes two essential functions in the SUMO pathway.  The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins.  The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein (By similarity).  May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway (By similarity).  Deconjugates SUMO2 from MTA1.  Plays a dynamic role in adipogenesis by desumoylating and promoting the stabilization of CEBPB (By similarity).  Acts as a regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS and STING1 during the late phase of viral infection (By similarity).
What are the official names of this protein?
Sentrin-specific protease 2, Sentrin/SUMO-specific protease SENP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Protein: PIGQ_MOUSE
Sequence: MVLKVFFPTCCASADSGLLVGRWVPGQSSAVILAVVHFPFIPIQVKELLAQVQKASQVPVAVLGTWCHRQQEPQESLGNFLEGLGTIFSHDPWLQLCRERGTRLWSCKATYPQMSNPLDMHPEEQVMLIFYDQRKLLLSWLHPPPVLPACQMGDTTASTGGLADIFDTVARSEVLFRNDQFDERPVRLSHWQSEGVEASILVELAKRASGPVCLLLASLLSLISAASACRLWKLWPLSFIRSKLSTCEQLHHRLKHLSFIFSTEKAQNPMQLMRKANMLVSVLLDVALGLLLLSWLHSNNRIGQLANALVPVADRVAEELQHLLQWLMGAPAGLKMNRALDQVLGRFFLYHIHLWISYIHLMSPFIEHILWHVGLSACLGLTVALSIFSDIIALLTFHIYCFYVYGARLYCLKIYGLSSLWRLFRGKKWNVLRQRVDSCSYDLDQLFIGTLLFTILVFLLPTTALYYLVFTLLRLLVITVQGLIHLLVDLINSLPLYSLGLRLCRPYRLAAGVKFRVLEKEAGRPLRLLMQINPLSYNHVMHIYRLPRCGCHPKHSWGTLCRKLVFGELIYPWRQREDKQD
What is the function of this protein?
Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q, MGpi1p, N-acetylglucosamyl transferase component GPI1, Phosphatidylinositol-glycan biosynthesis class Q protein, PIG-Q.
What is the protein family that this protein belongs to?
Belongs to the PIGQ family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: APH1_DICDI
Sequence: MTQVLFYGCLFITFSPILAFFFMVIAKNSQLVILTIGGSFFWLVSILIAAIWWYIIPPMREHWWFIISFSVLFQEIFRYIFFRLYSYGFNDRPSLNQIKETQHQMALDSMRKRKQAQQQKQQPPTNEIESINNEIIDTTNNNTNNNNNNNNNINDDDNKEITEEEKEKRKIEKQKQREIEINARLETLSARPNHTLSSAAIGVGSGVAYGFIMFGSILWESTGPGTLFSPACPSVNLFMLSSIITLFMTLLHVVYNVLAFQGYRSKKYHLVAFVIITHFVTTYLTLLNLPTKTTSCVGSILPIGIITVFSVGFCIFSLLKSDSITKIH
What is the function of this protein?
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors precursor protein.  It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex (By similarity).
What are the official names of this protein?
Gamma-secretase subunit Aph-1.
What is the protein family that this protein belongs to?
Belongs to the APH-1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZYG1_CAEEL
Sequence: MSGGKSGSRLSAYSHLKEIGKGGFGVVYAAQRENGEKVAIKRIDKKVPKNRVWTEIQTMKELKKSKYVVEFYEDFVEDGYTYIVMELCEGGSLQAYVREHGALDDATAVHVLRQLISAVSFMHRVNVIHRDLSAGNVFIKDSKKKKMTVKLGDFGLATTLGRGETTCTIVGTPGFIAPQVYDQEYTQSADVYSLGAVLYTMLTARNPPPKGLPPTCGMSPNAARLVEQMMDTDAKKRIPLTQIVLSEFMYENTNENAVIFSREHSRDGRRQRSREPVRSSRDDRSRDGRALIRSSSQPAHSGRAPLSNRPIHDRMPSTSSRGFDSERGRERDRDSGRGTVPPSREDRNRSQLWPIRMDRLEGQRVCTAGGRYIVELDTRCRFEVAAQGNFVKRILIVEVDEMVQTVYVHRIPDRTVRGRNGEEELITLTNNPFVYTSYSQMPKEVQNDYMRLQKMVAVTISGRVAKVTFRRPSQFPDAQAQLMENGDLRIKLPRSVIVRKMDNGEIFNCIDGIATQKQAVSGITLTKVNEVYKYLIRFEQCLNGMDRGMVCFPIVFSAGTNMVGSSPSSLMPSGSSQTSRFPFSNLSNNQPSLVPHSAPFLTKPTSSQRASSANVQRRVSTDENSSPSVAPSKYKIKIDPTTQKVRSIQATDGRVLRCSTSKADQFIFTDPAIRPDDQRFMRTDRVPDRASEMLHTLCERMRKLHQ
What is the function of this protein?
Protein kinase that plays a central role in centrosome duplication, control of centrosome size, spindle formation and nuclear envelope breakdown during cell divisions (PubMed:11371350, PubMed:15232593, PubMed:15665853, PubMed:19081077, PubMed:18765790, PubMed:19109417, PubMed:22623721, PubMed:27689799).  Paternal copy is required to regulate synthesis of daughter centrioles prior to fertilization (PubMed:11371350, PubMed:18765790).  Maternal copy regulates centrosome duplication during later cell cycles (PubMed:11371350, PubMed:18765790).  Functions upstream of sas-5 and sas-6, and is required for their localization to the centrosome (PubMed:15232593, PubMed:15665853).  Its role in nuclear envelope breakdown is mediated by the spindly-like protein spdl-1 and the RZZ complex, which in turn recruits the spindle checkpoint proteins mdf-1 and mdf-2, dynein and dynactin to unattached kinetochores (PubMed:18765790, PubMed:18936247).
What are the official names of this protein?
Probable serine/threonine-protein kinase zyg-1, Zygote defective protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Component of the centrosome (PubMed:11371350). Present at centrioles only immediately before their duplication (PubMed:11371350). Expression at centrosomes increases from prophase to anaphase during mitosis (PubMed:22623721).
Protein: NQOR_PARL1
Sequence: MTGKTKVLVLYHSSYGHIETLAKAVAEGAASQAGTEVLLKRVPETMPADAMANAGMKVEQEAPVATPQELGDYDAVIFGTPTRFGNMTGQMRTFLDQTGGLWAKGALVGKVGSVFTSTGTGGGNETTITSFHTNLFHHGMVVVGLPYSVGTELFDISEVRGGSPYGASTLAGGDGKRQPTEKELSLARKQGAHVASIAAKLKA
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: Y1161_PSEA6
Sequence: MLVTLTQSQARVIGVLLEKEVTTPEQYPLSLNSVTTACNQKSNREPVMELTELEVQNTLDELHAKNLIFEQSGSRATRYKHRFCNTEFSDLQLTPQQLAIICVMLLRGPQTPGELRTRAQRMAGFTHVDEVEKALNELMDVNGEQLVVRLEREPGKRESRYAQQFYKDTNEVISHEPAIASKSSQPNASNTTVATNDTAQEARICALEDTVTQLRCELEQLKQTLDELTR
What are the official names of this protein?
UPF0502 protein Patl_1161.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: FOLD_PSEA6
Sequence: MPAQKIDGKLIAQQVRQHVKSHVESIVSSGKRPPGLAVVLVGSDAASHVYVTNKRRACEEVGFVSKSYDLPSTTSQQKLLELIDTLNADEEIDGILVQLPLPAGLDKEQVLERILPHKDVDGFHPYNIGRLAQRIPALRPCTPKGIMTLIESTKRPIKGLDAVIVGASNIVGRPMFMELLLAGCTVTSCHKFTKDLQSHVERADLIVVAVGISAFIPGEWIKPGAIVIDVGINRQTDGTLIGDVDYATAEKRAGWITPVPGGVGPMTVASLIENTLEAYVKYHSN
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TRM61_DEBHA
Sequence: MSFFEYKDIIEEGDLVLAFLGRSNIKPITVTKGSQLNTRYGNFEHDRMIGMKYGEQMPGAKGVGFIHLLYPTPELWTVSLPHRTQIVYTPDSSYIIQRLNVTSGTRVIEAGTGSGSFSHSFARTIGVEGRLFTYEFHEPRYIEAKKELEDHGLLANTVITHRDVCNDGFEISNIPEDFKKDDGICGDVVFLDLPSPWTAIPNLKSVISHQSRVGICCFSPCIEQVEKTVKALETEGWSNIEMVEVAGKRWEARKDMVKDVKDVVKRLKDIQSRKNQGIEHRKQSKIHNVGDKRDIKEVETADDSSPEPTKFQNLGKGFNPFGKGLRVREGDEQFQWRNVTKIESEIKSHTSYLTFAYMNPNVRLNTSVE
What is the function of this protein?
Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, tRNA(m1A58)-methyltransferase subunit TRM61, tRNA(m1A58)MTase subunit TRM61.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CTPA_BARBK
Sequence: MIRKVIFFVAGVFLSASLIVMAQSITTNNEQNTYKQLARFGDIFERVRTQYVTIPDDQKLIENAINGMLLSLDPHSSYMDAEKAKDMRDSTKGEFGGLGIEVTMENNLIKVVSPIDDTPAAKAGVLAGDFISKIDGKQISGQTLNEAVDQMRGPAGTPITLTINRFGVDKPLDIKIVRDIIKVKAVKYRVEGDIGYLRLIQFTEKTFSDLQAAIKDIQSKIPTDKLKGYVLDLRLNPGGLLDQAISVTDAFLNKGEIVSTRGRKQNDVMRFDAKLGDLTDEKPIIVLINGGSASASEIVAGALQDHRRATIIGTQSFGKGSVQTIIPLGENGALRLTTALYYTPSGTSIQGIGITPDIVVEQPLPEKYKGYDVTLGESELRGHIKGKQESDKGSGSAAFVPRDPKDDVQLNEAYKLLRGEITHAAFPPDPNKVF
What is the function of this protein?
Involved in protection of the bacterium from thermal and osmotic stresses.
What are the official names of this protein?
Carboxy-terminal-processing protease, C-terminal-processing protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41A family.
What are the subcellular locations of this protein?
Secreted.
Protein: COPZ2_ARATH
Sequence: MSPDSCPLVKNILLLDSEGKRVAVKYYSDDWPTNAAKLSFEKYVFSKTSKTNARTEAEITLLDSNIIVYKFAQDLHFFVTGGENENELILASVLQGFFDAVALLLRSNVEKMEALENLDLIFLCLDEMVDQGVVLETDPNVIAGKVAMQSTEASGSLSEQTLTQALATAREHLARSLLT
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Coatomer subunit zeta-2, Zeta-2-coat protein, Zeta-COP 2.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: TRPF_STRPI
Sequence: MTKVKICGLSTEEAVETAVSAGADYIGFVFAPSKRQVTLEEAAELAKLIPSDVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQVDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQHFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.