PharMolix/UniProtQA huggingface dataset:
Protein: IF2_YERP3
Sequence: MTDVTVKSLAAEIQTPVDRLVQQFADAGIKKSDVDSVTQQEKEILLAHLNREHGSVPNKLTLQRKTRSTLNIPSTGGKSKSVQIEVRKKRTYVNTPEAEQAKAEEQAQREAEEQAQREAEATAQKIAEEKAKREAEEQAKREAAEKAKRQAAEKEKVTNQQTDEKTKPAQTDKARREAEAAELKRSVEEETRRKVEEDAKRVAEEARKMAAENEGKWPEPVAEQTESADYHVTTSQHARAAEDENDAKVEGDRRSRTRGGKATKQKKGNKLSESKADREEARAVGRKGKRKPSTLQQSFNKPVVAVNRDVVIGETVTVAELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEALMSDRDIGVEAAAEHRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAANVPVVVAVNKIDKPEADPDRVKTELSQYGIQPEEWGGESQFINVSAKAGIGIDELLNAILLQAEVLELKAVRTGMANGVVIESFLDKGRGPVATVLVQQGTLNKGDIVLCGFEYGRVRAMRDELGRDITSAGPSIPVEILGLSSVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVSELNIVIKSDVQGSCEAICDSLEKLSTDEVKVRIVGSGVGGITETDATLAAASGAIILGFNVRADASARRVVETEGLDLRYYSVIYSLIDEVKQAMSGMLAPEYKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGVIKRNNPIRVLRDNVVIYEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVRTGDVIEVFEIIEIKRTIA
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_NEUCR
Sequence: MRTYDDTFSGQRIYPGKGKLYVRGDSKIFRFQNGKSESLFLQRKNPRRIAWTVLYRRQHKKGISEEVAKKRSRRTVKAQRAIVGASLEVIKERRSMRPEARSAARLAAIKESKAKKQETQAAKKAEKAKNAANPKARVTSKQGAKGAPVKVAAKSR
What are the official names of this protein?
60S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
Protein: PGK_BRUAB
Sequence: MMFRTLDDANVQSKRVLVRVDLNVPMANGEVTDLTRIERIVPTIAELSRKGAKVILLAHFGRPKGVASDENSLKHVVKPLSKVLDHSVHFAEDCIGDKAKAAVDALKDGDVLLLENTRFHKGEEKNDPEFVQALAANGDLYVNDAFSAAHRAHASTEGLAHVLPAFAGRAMQAELEALEKGLGNPARPVVAIVGGAKVSTKLDLLSNLIEKVDALVIGGGMANTFLAAKGLDVGKSLCEHELASTAREIMAKAETTKCAIILPVDAVVGWHFAADTPHQTYGVDSVPGDAMILDAGELSTDLIASAIDDAATLVWNGPLGAFELRPFDTATVKVARHVAKRTKEGKLVSVGGGGDTVAALNHAGVADDFTYISTAGGAFLEWMEGKPLPGVDVLKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_PORG3
Sequence: MRKAKPKKRQILPDPVYGDVRVTKFVNHLMYDGKKNTAFSIFYGALDIVKTKLSNEEKSALEIWKAALDNITPQVEVKSRRIGGATFQVPTEIRPERKESISMKNLILYARKRGGKTMADKLAAEIVDAFNNQGAAFKRKEDMHRMAEANRAFAHFRF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SPB5_XENLA
Sequence: MDALRLANTGLAVDIFKKLCEKSATDNFVFSPICISTSLALLHRGSQGNTASELQKVLHFEKVKDSDFGFQLLSSDISKVISIYSLKLLKRVYVDNSIECKKDFINSTKKPYPLELETIDIKSRPEEARCQINSSVKELTDGNFEAVLNEGSCDEKTKIIMLGAASFKGNWVYKFNESETKEMDFHINKKETKPVQMMHLEARLSIGYINELKTMVLELPFTSKHLSILILLPKDIEDDSTGLKKLEQDMTFEKYAQWTNPSMMANSKVKVYLPKFKLESSFDLKDMLKSLGINDAFNEEASDFSGMTESKDTSISQAIHKACIEVNEDGTEAPDVTMERRLMNKEEFCADRPFIFILRHNKTRTIIMFGRYCGPCEASSTAD
What is the function of this protein?
May not exhibit serine protease inhibitory activity.
What are the official names of this protein?
Serpin B5.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: TSGA_SALPB
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFHLPVSSMSNTFTFLNAGILISIFLNAWLMEIIPLKTQLRFGFILMVLAVAGLMFSHSLALFSAAMFVLGLVSGITMSIGTFLITQLYEGRQRGSRLLFTDSFFSMAGMIFPMVAAFLLARSIEWYWVYACIGLVYLAIFILTFGCEFPALGKHAQHSQAPVVKEKWGIGVLFLAVAALCYILGQLGFISWVPEYAKGLGMSLNDAGALVSDFWMSYMFGMWAFSFILRFFDLQRILTVLAGMAAVLMYLFITGTQAHMPWFILTLGFFSSAIYTSIITLGSQQTKVASPKLVNFILTCGTIGTMLTFVVTGPIVAHSGPQAALLTANGLYAVVFVMCFALGFVSRHRQHSSPAAH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ROCA_BACMK
Sequence: MVVAYKHEPFTDFSVEANKLAFEEGLKKVESYLGQDYPLIIGGEKITTEDKIVSVNPANKEELVGRVSKASRELAEKAMQVADATFQTWRKSKPEMRADILFRAAAIVRRRKHEFSAILVKEAGKPWNEADADTAEAIDFMEYYARQMLKLKDGMPVESRPIEYNRFSYIPLGVGVIISPWNFPFAIMAGMTTAAVVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGVVNFVPGNGSEVGDYLVDHPRTRFVSFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGKDTIVVDKEADLELAAKSIVASAFGFSGQKCSACSRAVIHEDVYDHVLNRAVELTKELTVGNPDAKDINMGPVNDQAAFDKVMSYVAIGKEEGKIVSGGEGDDSKGWFIQPTIVADVAEDARLMKEEIFGPVVAFCKAKDFDHALAIANNTEYGLTGAVLSNNRDHIEKAREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLALHMQAKTTSETL
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: SECA_JANSC
Sequence: MLGLGSIAKKVFGSPNDRLVKSVRPIIAKINDMEPEFEALDDAGIVAKTAELRNRALNGEKLDDLLPEAFANCREAAKRALGLRAFDVQLIGGLFLHRGNIAEMKTGEGKTLVATFPAYLNGLTGEGVHVVTVNDYLAKRDSEWMGKVFTALGMTTGVVYPRQPDQEKRQAYACDVTYATNNELGFDYLRDNMRGSIAEMAQRGHNFAIVDEVDSILIDEARTPLIISGPTQDRSDLYMSIDKVIPLVQEHHYTLDEKTRQATFTDEGNDFLEETLSAEGILPEGQSLYDPESTTIVHHVTNALRAHKVFTKDKEYIVRDGEVVLVDEFTGRMMPGRRMSEGLHQAIEAKEGCKIQPENVTLASVTFQNYFRLYGTLGGMTGTATTEAEEFADIYGLGVVEIPTNRDIARIDDDDAVYRTGQEKYDAIVETIAEAHKKGQPVLVGTTSIEKSEMLGQLLTKADLPHSILNARQHEQEAQIVADAGKLGAVTIATNMAGRGTDIKLGGNLEFQIMEAIAADPDADPEEIRNRMEVEHATAEQAVKDAGGLYVLATERHESRRIDNQLRGRSGRQGDPGRSSFFLSLEDDLMRIFGSERLDKMLNTLGMKEGEAIVHPWVNKSLERAQAKVEGRNFDIRKQLLKFDDVMNDQRKVVFGQRRDIMGAEDIAEVAKDMRDQVIEDMVDTYMPPKTYADQWDVLGMKEAAQTTLGIDLPIEAWADEDGVDQEVATERLERAADEYMASKAAKFGPEQMRNIEKQVLLQTIDQKWQEHLLTLEHLRSVVGFRGYAQRDPLNEYKTESFQLFESMLDGLRTDVTEKLARIQPLTPEQQEQLMAQLRQQQAAAAGTEAVASAGGETGETAFPNAIPGFIEDDPSTWGNPGRNDDCPCGSGKKFKHCHGRLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: TCB1_YEAST
Sequence: MAKEDTGVTAPKKPETAQVANINGIDKLEPPKTKEETESSKSVSSEKAAHASDESFKRSIHEASYVGWKQIGGWEDKDELTLDDELMDMTRETFLDNIIPDSLYGDWYHSVAIFFIGGVASFALGHYKFSMGSAFFVIVITSLLYRTSAKKYRGSIRELVQKEFTVQKVENDYESLEWLNAFLDKYWPILEPSVSQLIVQQANEQMATNEAIPKFITQLWIDELTLGVKPPRVDLVKTFQNTASDVVVMDWGISFTPHDLCDMSAKQVRNYVNELAVVKAKIFGITIPVSVSDIAFKAHARVKFKLMTPFPHVETVNIQLLKVPDFDFVATLFGRSIFNWEILAIPGLMTLIQKMAKKYMGPILLPPFSLQLNIPQLLSGSNLSIGILEITVKNAKGLKRTSSILNESIDPYLSFEFNDISIAKTRTVRDTLNPVWDETLYVLLNSFTDPLTISVYDKRAKLKDKVLGRIQYNLNTLHDKTTQRNLKAQFLRNSKPVGELTFDLRFFPTLEEKKLPDGSVEELPDLNTGIAKVVVEEGSRFAEEEQKVTAYVEVYLNAKLVLTTGKATDTGTLKWNSDYEAVIADRRKTRYKFVVKDGKGEEIGSTIQTLNDLIDRSQVNKNLIPLKNQKGDIKITTYWRPVRLEIGSNSVAYTPPIGAIRVFIEKANDLRNLEKFGTIDPYCKVLVNGLSKGRTDFKSQTLNPVWNQVIYVAVTSPNQRITLQCMDVETVNKDRSLGEFNVNVQDLFKKDENDKYEETIDEKAKVGRLVMPKKKPKGTITYYTSFYPALPVLTLEEIQDLDKVNKKKKALELRKSAIDEKKISKEDKAKFDQEWNEVKELEDMYSNRQKLDLPELLQYNQGVLAVTVLNGELPDSGLYVQAFFDDNGHPRFVSPRIPSRIVKNGWSGDVIIKELDKSITTFRVAKNKNYNRVEKCVCEVELPTQELVKNCYYKPSILHLSGEGSAKLMLQISWFPIDTKQLPANDLITNSGDLTIMSRSAENLIASDLNGYSDPYLKYYINNEEDCAYKTKVVKKTLNPKWNDEGTIQINNRLNDVLRIKVMDWDSTSADDTIGTAEIPLNKVKVEGTTELDVPVEGLENAGQDGGMLHLAFSFKPRYTISVSKREKKVGDIASKGLGTGLKAGTTVIGGGVGAIGKIKKGVFGGLGSLTNHKKNHEMGEEETKF
What is the function of this protein?
May play a role in membrane trafficking.
What are the official names of this protein?
Tricalbin-1.
What is the protein family that this protein belongs to?
Belongs to the tricalbin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=More enriched in the cortical endoplasmic reticulum (ER) that is closely apposed to the cell membrane than in the perinuclear ER or internal ER tubules that connect the nucleus to the cortical ER.
Protein: NMD3_BOVIN
Sequence: MEYMTDPVKHTPGHILCCDCGVPISPNPANICVACLRSKVDISQGIPKQVSISFCKQCQRYFQPPGTWVQCALESRDLLALCLKKIKAPLSKVRLVDASFVWTEPHSKRLKVKLTIQKEVMNGAILQQVFVVDYVVQPQMCGDCHRVEAKDFWKAVVQVRQKTLHKKTFYYLEQLILKYGMHQNTLRIKEIHDGLDFYYSSKQHAQKMVEFLQCTVPTRYKASQRLISQDIHSNTYNYKSTFSVEIVPICKDNVVCLSPKLAQSLGNMNQICVCIRVTSVIHLIDPNTLQVADIDGNTFWSHPFNSLCHPKQLEEFIVMECSIVQDIKRSAGAGMISKKHTLGEVWVQKTSEMNTDKQYFCRTHLGHLLNPGDLVLGFDLVNCNLNDEHVNKMKSDRVPDVVLIKKSYDRTRRQRRRNWKLKELARDRENTDTDDERQYQDFLEDLEEDEAIRKNVNIYRDSTIPVESDTDDEGAPRISLAEMLEDLHISQDATGGEGESMMT
What is the function of this protein?
Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
What are the official names of this protein?
60S ribosomal export protein NMD3.
What is the protein family that this protein belongs to?
Belongs to the NMD3 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
Protein: SECB_STRM5
Sequence: MSEETTNGAVAPADAATGPAFTVEKIYVKDVSFESPNAPTIFNDQVQPELQLNLNQQVQRLGENAFEVVLAVTLTCQAGERTAYVAEVKQAGVFGLVGLDPQSIDVLLGTQCPNILFPYVRQLISDLIQAGGFPPFFLQPINFEGLYAETLRQRQEQGDAPSLADSEPAGNA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMF_SALPC
Sequence: MAQHAVYFPDAFLTQMREAMPSTLSFDEFISACQRPLRRSIRINTLKISVADFLALIAPYGWSLTPIPWCHEGFWIERDDEEALPLGSTAEHLSGLFYIQEASSMLPVAALFADDNHPQRVMDMAAAPGSKTTQIAARMGNRGTILANEFSASRVKVLHANISRCGIANTALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNLDIAATQRELLDSAFHALRPGGTLVYSTCTLNRQENEAVCLWLKETYADAVEFLPLGDLFPDADRALTPEGFLHVFPQIYDCEGFFVARLRKMSSLPAMPAPGYKVGAFPFTPLKGREALHVTQAANAVGLLWDENLHLWQREKEVWLFPAEIESLIGKVRFSRLGIKLAESHNKGYRWQHEATIALACPTHAHAFELSVQEAEEWYRGRDIYPQTPPAADDVLVTFQHQPLGLAKRIGARIKNSYPRELVRDGKLFTGNS
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_PLAVS
Sequence: MNIFQHDIQDVGQGNVVAILGSQWGDEGKGKIIDILSKHSDITCRFNGGSNAGHTISVNDKKYALHLLPCGILYENNICVLGNGMVVHVKSLIDEINSIGGNIIDRLYLSDKSHILFDIHQTIDSMQENKKLKEGKQIGTTKRGIGPCYSTKVSRVGIRLGSLKNFEHFKSLYVKLIDNLMELYNISDYNKEEELEAFYQYHLLLKDRIIDVISFMNNQLNEKKKILIEGANAAMLDIDFGTYPYVTSSCTTVGGIFSGLGINHKKLNLTVGVVKSYLTRVGCGPFMTELTNEIGDYLREKGYEYGTTTKRPRRCGWLDIPMLLYVKCINSIDIINLTKLDVLSGLKEISLCVGYRSKATGELLQKGCYPVDEDAPEHYEPVYEQFEGWEEDISNCESFEELPENARKYVLAIEKYVGSPIVWIGIGANRNNTIMKK
What is the function of this protein?
Plays an important role in the salvage pathway for purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHBP_CAMJE
Sequence: MKFETINQESIAKLMEIFYEKVRKDKDLGPIFNNAIGTSDEEWKEHKAKIGNFWAGMLLGEGDYNGQPLKKHLDLPPFPQEFFEIWLKLFEESLNIVYNEEMKNVILQRAQMIASHFQNMLYKYGGH
What is the function of this protein?
Has been suggested to be involved in cytochrome c peroxidase or P450-like oxygen chemistry or cyanide detoxification.  The high oxygen affinity of this protein suggests that it probably does not function as an oxygen transporter.
What are the official names of this protein?
Group 3 truncated hemoglobin ctb, Cj-trHbP, Truncated Hb.
What is the protein family that this protein belongs to?
Belongs to the truncated hemoglobin family. Group III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_CHRSD
Sequence: MAAISASLVKELRERTGLGMMECKKALTEADGDIETAIENLRKNSGLKAAKKAERTAAEGGVVTRVAEDGTYGVMLEVNSETDFVARDDNFTAFAEKVVGKVFEAKSDDVASLMEGELEEAREQLVQKIGENISVRRAVVVEAPAGGVVGAYVHGGRIGVLTVLKGGNAEVAKDVAMHVAAINPSVAHPEDMPQAELDSEKAIILAQPDMAGKPAEIAEKMVQGRLKKYLAENSLTEQPFVKDPNQSVAEYVKAAGGEVVGFTRFEVGEGIEKEEVDFAQEVMEQARRS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_PSEPK
Sequence: MSASTTATTRHDWALAEVKALFQQPFNDLLFQAQTVHRAHFDPNRVQVSTLLSIKTGACPEDCKYCPQSGHYNTGLEKQKLMEVQKVLEEAARAKAIGSTRFCMGAAWKHPSAKDMPYVLEMVKGVKAMGLETCMTLGKLDQEQTKALAQAGLDYYNHNLDTSPEFYGSIITTRTYSERLQTLAYVRDAGMKICSGGILGMGESLDDRAGLLIQLANLPEHPESVPINMLVKVAGTPLAEEEDVDPFDFIRMLAVARILMPKSHVRLSAGREQMNEQMQALAFMAGANSIFYGEKLLTTANPQADKDMQLFARLGIKPEAREEHADEVHQAAIEQALVEQRSSEMFYDAATA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: EXO5_YEAS6
Sequence: MLGRTLINKHGFLIHPRRFVHLNDKSLDGTFILPSKKNHMYDVPTNDPSGILNASDIDRINNLPFFDNTSPTKETNTKEGALLSEKLASVKELFGEDPENPSFINYRFPRGLENPYFDIQVNQLKKKRLSVTQLCTTQNWCELRNFYDFYSQNLSNQLLNLKFQVQKGKKIHKSLEDETHPELNQYKSFTHNFLALTKLSMDIDNDMDALLDNWFNSINRLVSLFTKGDGHAREIVCHGFINLEDGKLVEHLLNSDSKTKENVIISGVIDHLTLRNKHNHQVQKGAAHLDTEYQSWGNILTNLLSNLKELKSNNEIVISDIKTRSVPKIPSIESVIESSKLQTMYYKFFFSHLSQDMTQTYHSFLINAKRRGLDVDAPINPTKILTFILTNPLFANDVKNLLYGLPINHSAFDNDAKGSNTFDMAAFNDLLDRGPTSFNVPIEQDEDSSESTKCVSLRDYGHFYTKWKTPLTLKYFAARLSQIYFIVGNLVSNDLMIEYYYHNDNFHNIIFPYDTLKLGTHAHDSAMVWFGGRDMHPIEPTQKNFNTYCKFCDYRHVCSWKNKNELKLIDLGKELKKIILESSMK
What is the function of this protein?
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FNBP4_HUMAN
Sequence: MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATTTTTAVTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAITAPQPAAPVGASAPPPTPPRPEPKEAATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKKEVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKEEPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEEQDTLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWKMFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRARLKRRKMAPNT
What are the official names of this protein?
Formin-binding protein 4, Formin-binding protein 30.
Protein: Y242_SALRD
Sequence: MPYPKSMVEPMRKELTRLGIDELKSPDDVDAAFGAAEDETLLLIINSVCGCAAGGARPAVAQALETGPTPDHAVTVFAGQDVAATDYVRDTHLPGIPPSSPFMALFRNGQPVYVIERKHIEGREPAAISADLVEALQAYCTDEAPPSDAPSRPDLSSSPNAGGLPSTFQSIS
What are the official names of this protein?
UPF0403 protein SRU_0242.
What is the protein family that this protein belongs to?
Belongs to the UPF0403 family.
Protein: VATC_THEON
Sequence: METGAVTGILNTTLAVVFTWVGYKTARIVWKYTPYSYPNARIKAMEAKLLSEQRFNELAESRTLNNFVVSLEDTDYKDYLASVSNYTVEEIERALERALAGTYELMVTILPKRVNPFFRLLLEEWDVRNITSVIKAKMVNEPASDYVVEIGTMLPKVKAMAEAKTMEEILVILEGTPYEEPYQKLLLGEISLKEFETELYRMYYAKLLNYALSKKEDERVILEEFVRLKIDKTNILTLLRAKAAKMGAEEIKPLIIPGGTIKLDSILHVDDLSMALAELDSTRYGAVIRDVREEVERDLSVLERALDRHIRERMNELTRFYPLSVATPLSYILQKEREVRKLRAIAKLIDDGVEPERIKELVGDAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit C, V-ATPase subunit C.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase V0D/AC39 subunit family.
Protein: AMPE_MOUSE
Sequence: MNFAEEEPSKKYCIKGKHVAIICGVVVAVGLIVGLSVGLTRSCEQDTTPAPSQPPPEASTALPPQDQNVCPDSEDESGEWKNFRLPDFINPVHYDLEVKALMEEDRYTGIVTISVNLSKPTRDLWLHIRETKITKLPELRRPSGEQVPIRRCFEYKKQEYVVIQAAEDLAATSGDSVYRLTMEFKGWLNGSLVGFYKTTYMEDGQIRSIAATDHEPTDARKSFPCFDEPNKKSTYSISIIHPKEYSALSNMPEEKSEMVDDNWKKTTFVKSVPMSTYLVCFAVHRFTAIERKSRSGKPLKVYVQPNQKETAEYAANITQAVFDYFEDYFAMEYALPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDPLLSASSNQQRVASVVAHELVHQWFGNTVTMDWWDDLWLNEGFASFFEFLGVNHAEKDWQMLSQVLLEDVFPVQEDDSLMSSHPVVVTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLKKFQFANAKTSDFWDSLQEASNLPVKEVMDTWTSQMGYPVVTVSGRQNITQKRFLLDSKADPSQPPSELGYTWNIPVRWADNDNSRITVYNRLDKGGITLNANLSGDAFLKINPDHIGFYRVNYEGGTWDWIAEALSSNHTRFSAADRSSFIDDAFALARAQLLNYKIALNLTMYLKSEEDFLPWERVISSVSYIISMFEDDRELYPMIETYFQGQVKPVADLLGWQDTGSHITKLLRASILGFACKMGDREALGNASQLFDSWLKGSASIPVNLRLLVYRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVKLLARYLEMLKDPNIIKTQDVFTVIRYISYNSYGKTMAWNWIQLNWDYLVSRFTINDRYLGRIVTIAEPFNTELQLWQMQSFFAKYPNAGAGAKPREQVLETVKNNIEWLNVNRQSIREWFASLP
What is the function of this protein?
Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.
What are the official names of this protein?
Glutamyl aminopeptidase, EAP, Aminopeptidase A, AP-A, BP-1/6C3 antigen.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: YIPF5_RAT
Sequence: MSGFDNLNSGFYQTSYSIDEQSQQSYDYGGSGGPYSKQYAGCEYSQQGRFVPPDMMQPQQTYTGQIYQPTQAYPPPTPQTFYGDSFEEEPPLLEELGINFDHIWQKTLTVLHPLRASDGSIMNETDLAGPVVFCLAFGATLLLAGKIQFGYVYGISAIGCLGMFCLLNLMSMTGVSFGCVASVLGYCLLPMILLSSFAVVFSLQGMVGILLTATIIGWCSFSASKIFISALAMDGQQLLVAYPCALLYGVFALISVF
What is the function of this protein?
Plays a role in transport between endoplasmic reticulum and Golgi.  In pancreatic beta cells, required to transport proinsulin from endoplasmic reticulum into the Golgi (By similarity).
What are the official names of this protein?
Protein YIPF5, YIP1 family member 5, YPT-interacting protein 1 A.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle. Note=Enriched at the endoplasmic reticulum exit sites. Incorporated into COPII coated vesicles.
Protein: ZN189_HUMAN
Sequence: MASPSPPPESKGLLTFEDVAVFFTQEEWDYLDPAQRSLYKDVMMENYGNLVSLDVLNRDKDEEPTVKQEIEEIEEEVEPQGVIVTRIKSEIDQDPMGRETFELVGRLDKQRGIFLWEIPRESLTQEQRMFRENTNIIRKRPNSEEKCHKCEECGKGFVRKAHFIQHQRVHTGEKPFQCNECGKSFSRSSFVIEHQRIHTGERPYECNYCGKTFSVSSTLIRHQRIHTGERPYQCNQCKQSFSQRRSLVKHQRIHTGEKPHKCSDCGKAFSWKSHLIEHQRTHTGEKPYHCTKCKKSFSRNSLLVEHQRIHTGERPHKCGECGKAFRLSTYLIQHQKIHTGEKPFLCIECGKSFSRSSFLIEHQRIHTGERPYQCKECGKSFSQLCNLTRHQRIHTGDKPHKCEECGKAFSRSSGLIQHQRIHTREKTYPYNETKESFDPNCSLVIQQEVYPKEKSYKCDECGKTFSVSAHLVQHQRIHTGEKPYLCTVCGKSFSRSSFLIEHQRIHTGERPYLCRQCGKSFSQLCNLIRHQGVHTGNKPHKCDECGKAFSRNSGLIQHQRIHTGEKPYKCEKCDKSFSQQRSLVNHQKIHAEVKTQETHECDACGEAFNCRISLIQHQKLHTAWMQ
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 189.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FRHA_METBF
Sequence: MTKVVEISPTTRLEGHSKLTLKVDDQGIVERGDWLSITPVRGIEKLAIGKTMEQVPKIASRVCGICPIAHTLASTEAMEASIGCEIPTDAKLLRTILHAANRIHSIALHNILILPDFYIPGTEKKFNLFANEQPARSVMARIVRIREIAQTIGAIAGGEAIHPSNPRIGGMYYNVSPRAKQKMADLAKEGLVLVHEQMEFMFDVIRNMQNREFVEVAGKQIPLPKKLGYHNQGVMATASMYGSSSLDDNPTWDFTRWKETRPWDWYMGEVTIDLEDPSYPIGGTTKIGTKANPQMEACTGVPTYDGQPVEVGPRARLATFKNFDEKGTFAQHIARQMEYPDCCYTILRCLDNLNTSGKVLADHIPQGDGSMGWAANEAPRGSNIHLARVKDGKVLWYDMLVPTTWNFPTCSRALTGAPWQIAEMVVRAYDPCVSCATHMIVVNEEEKIVTQKLMQW
What is the function of this protein?
Reduces the physiological low-potential two-electron acceptor coenzyme F420, and the artificial one-electron acceptor methylviologen.
What are the official names of this protein?
Coenzyme F420 hydrogenase subunit alpha, 8-hydroxy-5-deazaflavin-reducing hydrogenase subunit alpha, FRH.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RNPH_BACVZ
Sequence: MRHDGRQHDELRPITFDLDFITHPEGSVLITAGNTKVICNASVEDRVPPFLRGGGKGWITAEYSMLPRATNQRTIRESSKGKVSGRTMEIQRLIGRALRAVVDLEKLGERTIWIDCDVIQADGGTRTASITGAFLAMAIAIGKLVKSGVIKTSPVTDYLAAISVGMDKEEGLLLDLNYEEDSAAEVDMNIIMTGSGRFVELQGTGEEATFSREDLNGLLSLAEKGIQTLIQKQKEVLGETLPELK
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: LY6L_HUMAN
Sequence: MERLVLTLCTLPLAVASAGCATTPARNLSCYQCFKVSSWTECPPTWCSPLDQVCISNEVVVSFKWSVRVLLSKRCAPRCPNDNMKFEWSPAPMVQGVITRRCCSWALCNRALTPQEGRWALRGGLLLQVGLSLLRALL
What are the official names of this protein?
Lymphocyte antigen 6L, Lymphocyte antigen 6 complex locus protein L.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.