PharMolix/UniProtQA huggingface dataset:
Protein: HZSA_KUEST
Sequence: MGKRKLGVIASAFVAGALVCGSTLVNAEPVMTGGPVQGKALWTDYSGMSKEVQGPVSQILFTQSPRTAKGDPYQNYPHYIPEGSRIVLFDLNTKELKVLTNDFATAFDPCTYWDGKKFAFAGVHKKGGGCQIWEMNIDGSGLRQMTDLKGTCRSPIYYAAGSIEEGEGRIIWRDRYFEGDWKEHGMVEKTGMIIFSGSPEGVMDEFHNPYAYNLYRLDTQGGKIIQRITGHVLSGIEFPHLNTTIDQITYNLSSNFDPWLTPDGNILFSSVQANGSRAGGEGRVMICVDNWDGAYPRPIYGNCDGEIGGTSGRSQAKITFGDRKIVYVESPYMNWGVGQLAAVSWDAPFNKTYEKLTGKDGGLYRSPYPLPDDRMLVSYAERGDFGIYWFNFSKCAAGDKVYDDPNWNDHQPAPVYVKYKPRWINTFTAGKNFGVTVVTYQPFDQVKVEGYPHSWGTWICFDTTLSDQPVGPYPHQKAKNVSHGDIKAVRIIQGYQCVEPDSTRFRVGAGAHLLGGERSSSNSGTAFQQRGIIGYQYVESDGSTVTSQLSDVPYYMQILDDKGMSVQTALTWAYLRPYHGRICSGCHYGSYRGRAFKNIHAKALYNWWYDDRSHYDSPFAFRYLKFDNDGNYKGVKHGEDVVVPSDIYYGGPSGTTSQPVEGLTLDKQRTVDFRRDIQPILDAKCAMCHDSNNPPNLGGGLELVSVDGIAAYSRAYNSLLEPQRGKDPNIGGKYVNPSAAINSLLVWRLYEAELSANAPREKIFPIEGRLLHNKFLTQDERYAIVEWIDLGAQWDNIPGPDFYPGYLVK
What is the function of this protein?
Component of the hydrazine synthase complex that catalyzes the condensation of nitric oxide (NO) with ammonium to form hydrazine (PubMed:21964329).  The alpha subunit catalyzes the second half-reaction, i. e.  the condensation of hydroxylamine formed in the active site of the gamma subunit with ammonia, yielding hydrazine (PubMed:26479033).  Is involved in anaerobic ammonium oxidation (anammox), a biological process in which nitrite is used as the electron acceptor in the conversion of ammonium to dinitrogen gas (N2) and water; this bacterial process has a major role in the Earth's nitrogen cycle and has been estimated to synthesize up to 50% of the dinitrogen gas emitted into our atmosphere from the oceans (PubMed:21964329, PubMed:26479033).
What are the official names of this protein?
Hydrazine synthase subunit alpha, HZS-alpha.
What are the subcellular locations of this protein?
Anammoxosome.
Protein: MALT_SALTI
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLLLVTSPAGYGKTTLVSQWAAGKNELGWYSLDEGDNQQERFASYLIAAIQQATGGHCSTSEAMAQKRQYASLTSLFAQLFIELAQWHRPLYLVIDDYHLITNPVIHDAMRFFLRHQPENFTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLSSPIEAAESSRMCDDVAGWATALQLIALSARQNHTSAHHSARRLAGINASHLSDYLVDEVLDNVDVSTRHFLLKSAILRSMNDALIVRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFSYHPLFGSFLRQRCQWELAAELPEIHRAAAESWMEQGFPSEAIHHALAAGDAQMLRDILLNHAWGLFNHSELALLEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGVMDGTLHAEFNALRAQVAINDGNPEEAERLAKLALDELPLAWFYSRIVATSVHGEVLHCKGNLSQSLSLMQQTEQMARHHDVWHYALWSLIQQSEIQFAQGFLQAAWETQERAFQLIKEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIAVLSTFQPQQQLQCLTLLVQCSLARGDLDNARSQLNRLEKLLGNGRYHCDWISNADKVRVIYWQLTGDKKSAANWLRHTPKPAFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQSGRKNDAQRVLLDALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPEMEQHRAQRILRYINQHHRHKFAHFDEGFVERLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELAVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: LAP4_TRIVH
Sequence: MKIATLAVVSAFAATAIAGPIRPDGVGNDKFLIELGPGETQWVTKQQKHEMRAYINSIYKAGQGFVDITDEFGTDFTTAEVVPANYPKSALHAAVVNPMIAGLSKENLMRDLNTLVKFNNRYYESPTGVESATWVFNEVQKIIQASGVKGAKVEKFTNKFKQFNVIATIPGASKNTVIVGAHQDSINQKDPMKGRAPGADDNGSGTVVVLEAFRNVLKSKAIQAANATNTLEFHWYAGEEGGLLGSNNIFKKYKADGRKVKAMLNQDLTGFTKKGNPEQFGLITDNTNAELNEFCKTIVAKYAALKIVEAKCGYACSDHASAHRNGFPSSFIAETNFRNTNPYLHTADDVIANLDFNHMLEHAKVVVGFMGELAMTPNL
What is the function of this protein?
Probable extracellular aminopeptidase which contributes to pathogenicity.
What are the official names of this protein?
Probable leucine aminopeptidase TRV_05286, Leucyl aminopeptidase TRV_05286.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR7_VIBC1
Sequence: MSLANQVLAVNDDLPIRTHKPVHSGKVRSVYWLTEEDSARLIKEKGYDVAPDAPLAIMVISDRISAFDCIWHGEGGLKGVPGKGAALNAISNHWFKLFKDNGLADSHILDIPHPFVWIVQKAKPVKIEAICRKYITGSMWRAYANGEREFCGIELPEGLEKDKALPELLMTPSTKGILKGIPGVPEADDVNITRQNIVDNFEAFNFSNAKDIAQYEKLLKEGFNVISSALEAIDQTFVDTKFEFGYVHDAAGNEKLIYMDEVGTPDSSRIWDTKEYQAGNIVENSKEGFRQFLLSHFPDPDILLNKERMPEREALARDNELPVESLMDISRTYIGIAEKITGQPIKLSNDPKAEIIEILSKEYGLID
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: SRCRL_HUMAN
Sequence: MRVLACLLAALVGIQAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAPWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGPPGLDSISDPFSWSWIPGLGRDRDAWLPGELATKPSASVTASVLEKTTTKAPGKMPKSTKKWVTKNAKRPTTQPPVMPTTKHSRAQSPPDLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIRRLPDTGSKDGYKLPWTWDTPSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSPNLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTPPVRVMACEPPALVELVAAVRDVGGQLQRLTQVVEQERQERQALLLGLTQLVEAARGLGQLGEAVKRLAEMAWTTSMPAPTTTTPEEEERPLRGDV
What is the function of this protein?
Binds to extracellular matrix proteins.  Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR).  Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release.  Does not possess intrinsic bactericidal activity.  May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity).
What are the official names of this protein?
Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D, Soluble scavenger protein with 5 SRCR domains, SSc5D.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: FIS_SHEPA
Sequence: MFDQTTHTEVHPLTVGKIETASGAIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSEVEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: VIM1_CARAU
Sequence: DLTEAANKSNEALRLAKQESNDYRRQVQALTCEVDALKGTNESLERQMREMEENFAMESSSSQDKIVQLEEDTQNMKDEMAKHLHEYQDLLNVKMALDIEIATYRKLLEGEESRISTPLPNFSSFNLRETMLELKPNIESTFTKKVLIKTIETRDGQVLNESTQNHDDLE
What is the function of this protein?
Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.  Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.
What are the official names of this protein?
Vimentin A1.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: LIGO4_MOUSE
Sequence: MDAATAPKQAWLPWSPLLFLLLLPGGSISSCPTVCDCTSQTRAVFCAHRRLDTIPGGLPLDTELLDLSGNRLWGLQRGMLSRLGQLQELDLSYNQLSTLEPGAFHGLQSLLTLRLQGNRLRIVGPGIFSGLTALTLLDLRLNQIVLFLDGAFSELGSLQQLEVGDNHLVFVAPGAFAGLAKLSTITLERCNLSTVPGLALAQLPALVALRLRELDIERLPAGALRGLGQLKELEIHHWPSLEALDPGSLVGLNLSSLAITRCNLSSVPFQALHHLSFLRILDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQTLEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPACAGPQHVQGKSLREFSDILPPGHFTCKPALIRKSGPRWVIAEEGGHAVFSCSGDGDPAPTVSWMRPQGAWLGRVGRVRVLEDGTLEIRSVQLRDRGAYVCVVSNVAGNDSLRTWLEVIQVEPPNGTLSDPNITMPGIPGPFFLDSRGVAMVLAVGFLPFLTSVTLCFGLIALWSKGKGRVKHHMTFDFVAPRPSGDKNSGGNRVTAKLF
What are the official names of this protein?
Leucine-rich repeat and immunoglobulin-like domain containing-NOGO receptor-interacting protein 4, Leucine-rich repeat neuronal protein 6D.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ERGI1_DANRE
Sequence: MSFDVRRFDIYRKVPKDLTQPTYTGAFISICCCVFMLFLFLSELTGFIATEIVNELYVDDPDKDSGGKIDVSLNISLPNLHCDLVGLDIQDEMGRHEVGHIENSMKVPLNNGHGCRFEGEFSINKVPGNFHVSTHSATAQPQSPDMTHIIHKLAFGAKLQVQHVQGAFNALGGADRLQSNALASHDYILKIVPTVYEELGGKQRFSYQYTVANKEYVAYSHTGRIIPAIWFRYDLSPITVKYTERRRPFYRFITTICAIIGGTFTVAGIIDSCIFTASEAWKKIQIGKMS
What is the function of this protein?
Possible role in transport between endoplasmic reticulum and Golgi.
What are the official names of this protein?
Endoplasmic reticulum-Golgi intermediate compartment protein 1, ER-Golgi intermediate compartment 32 kDa protein, ERGIC-32.
What is the protein family that this protein belongs to?
Belongs to the ERGIC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi- pass membrane protein.
Protein: Y2904_METPP
Sequence: MLHYAVVFFIIALIAAVFGFGGIAASAAGIAKILFFVFVVLAVASFLFGLIRKG
What are the official names of this protein?
UPF0391 membrane protein Mpe_A2904.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL15_LISMF
Sequence: MKLHELKPSEGSRKERNRVGRGTGSGNGKTSGRGHKGQKARSGGGVRLGFEGGQLPLFRRIPKRGFTNINRKEFAIVNLDVLNRFEDGTEVTPELLVETGIIRNEKSGIKILSNGNIEKKLTVKANKFSAAAKEAIEAAGGKTEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PCRA_STAAN
Sequence: MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
What is the function of this protein?
Essential helicase.
What are the official names of this protein?
ATP-dependent DNA helicase PcrA, DNA 3'-5' helicase PcrA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: TS1R2_RAT
Sequence: MGPQARTLCLLSLLLHVLPKPGKLVENSDFHLAGDYLLGGLFTLHANVKSISHLSYLQVPKCNEFTMKVLGYNLMQAMRFAVEEINNCSSLLPGVLLGYEMVDVCYLSNNIHPGLYFLAQDDDLLPILKDYSQYMPHVVAVIGPDNSESAITVSNILSHFLIPQITYSAISDKLRDKRHFPSMLRTVPSATHHIEAMVQLMVHFQWNWIVVLVSDDDYGRENSHLLSQRLTKTSDICIAFQEVLPIPESSQVMRSEEQRQLDNILDKLRRTSARVVVVFSPELSLYSFFHEVLRWNFTGFVWIASESWAIDPVLHNLTELRHTGTFLGVTIQRVSIPGFSQFRVRRDKPGYPVPNTTNLRTTCNQDCDACLNTTKSFNNILILSGERVVYSVYSAVYAVAHALHRLLGCNRVRCTKQKVYPWQLLREIWHVNFTLLGNRLFFDQQGDMPMLLDIIQWQWDLSQNPFQSIASYSPTSKRLTYINNVSWYTPNNTVPVSMCSKSCQPGQMKKSVGLHPCCFECLDCMPGTYLNRSADEFNCLSCPGSMWSYKNDITCFQRRPTFLEWHEVPTIVVAILAALGFFSTLAILFIFWRHFQTPMVRSAGGPMCFLMLVPLLLAFGMVPVYVGPPTVFSCFCRQAFFTVCFSICLSCITVRSFQIVCVFKMARRLPSAYSFWMRYHGPYVFVAFITAIKVALVVGNMLATTINPIGRTDPDDPNIMILSCHPNYRNGLLFNTSMDLLLSVLGFSFAYMGKELPTNYNEAKFITLSMTFSFTSSISLCTFMSVHDGVLVTIMDLLVTVLNFLAIGLGYFGPKCYMILFYPERNTSAYFNSMIQGYTMRKS
What is the function of this protein?
Putative taste receptor.  TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
What are the official names of this protein?
Taste receptor type 1 member 2, G-protein coupled receptor 71, Sweet taste receptor T1R2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TLP20_SPIOL
Sequence: SAEETPLQSKVTNKVYFDISIGNPVGKVVIGLFGDDVPQTAENFR
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase TLP20, chloroplastic, PPIase, P18, Rotamase, Thylakoid lumen PPIase of 20 kDa, Thylakoid lumenal 18 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: COMM2_DROME
Sequence: MEELPRALNYELSHDLHFDHYAGAAAQKILNSGRSSPEASTPTITTLDAISSSDFLKQIGQQILSSIQLKHQHQLNEVSHPRNSTSEEIMDFDLANRVILDSSSVDQLQQQLEYDKFMNEVWIGIVFTLILISMVFCICSCFLYHQFRTWKRNYRNNANGSTQCTIVDIEALKLHPDVEDPVPEYTLVSGLPSYEAALELLQKSPQSSCLIVYPSVFNVFNKQERSSQELQHPGVATSAPPAAPENHLAPQTPSFCDATMPLLPATTAAAATHAAATVTAVTAATATSATLAASPTCESIKPNFVMMPIVPSYAEVFGSSYKTVDEKKKSKSKDSQSKDDIKR
What is the function of this protein?
Essential for nerve cord development.  Functions downstream of fra to control axon guidance across the central nervous system (CNS) midline.
What are the official names of this protein?
Protein commissureless 2.
What is the protein family that this protein belongs to?
Belongs to the commissureless family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GCSP_BORPD
Sequence: MSRALDPHTDFIPRHIGPTAADQEKMLAAIGCGSLDALLQEVVPPAIRSQGPLALPASRSESDVLADLKAVAGRNRIYRNYIGQGYYGTHTPNVVLRNVLENPAWYTAYTPYQPEISQGRLEALLNYQTMVADLTGLDISNASLLDEGTAAAEAMTLARRGSKSASQVFFVSAHCHPQTIEVVRTRAEGLGIEVALGDEAQGLPECFGVLLQYPHSLGGVADYRALAEAAHAQGAVVACATDLLALALMTPPGEWGADIAIGSSQRFGVPFGFGGPHAGFMACKDAYKRNMPGRLVGVSKDAQGNPALRLALQTREQHIRREKATSNICTAQVLLAVMAGLYAVWHGPDGIRRIATRVHRYTAILRAALTQLGIKVVNDTFFDTLLLETGVATPAIVEAAVCEHINLRRVDGARLAVSLDETVTAADLQALVNVFAAGLQKDDLALDIDAHDAAAPGGIPAALQRQGGILAHPVFSSIQSETDMLRYLRKLADKDLALDRSMIPLGSCTMKLNATAEMIPITWPEFALIHPYAPADQSAGYRELIERLSKALCEITGYDDISLQPNSGAQGEYAGLLAIRGYHRANGQAQRNVCLIPASAHGTNPASAQLAGMEVVVVASDANGNVDLDDLRAKLTQVGDRLAALMITYPSTHGVFEESITHICDLVHQAGGQVYLDGANMNAMVGVARPGKFGSDVSHLNLHKTFCIPHGGGGPGVGPVAVRSHLAPFLPGVLNAQGKLGGETGIGPVAAAPYGSAGILPISYAYIALMGADGLRRATEVAILNANYVAARLRDYYPVLYAGRNGRVAHECILDVRPLKDSSGISAEDIAKRLMDYGFHAPTMSFPVAGTLMVEPTESEGLAELERFIDAMIAIREEIAQVERGERDRDDNVLKNAPHTAQMLLAEEWLHDYPRQQAAYPVASLRDAKYWPPVARVDNAYGDRNLVCACLPVEAYA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: PRSA2_LISIN
Sequence: MKKKLILGLVMMMALFSLAACGGGGNVVKTDSGDVTQDELYDAMKDKYGSEFVQQLTFEKILGDKYKVSDEDVDKKFKEYKSQYGDQFSAVLAQSGLTEKSFKSQLKYNLLVQKATEANADTSDKALKEYYKTWQPDITVSHILVADENKAKEVEQKLKDGAKFADLAKEYSTDTATKENGGQLAPFGSGKMDPAFEKAAYALKNKGDISAPVKTQYGYHIIQMDKPATKTTFDKDKKAVKEAYLASQLTTENMQKTLKKEYKDANVKVEDKDLKDAFKDFDGSASKDSSK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 2.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RN114_BOVIN
Sequence: MAAQAQAPARDGGAQLAGPAAEADPLGRFTCPVCLEVYEKPVQVPCGHVFCSACLQECLKPKKPVCGVCRSALAPGVRAVELERQIESTETSCHGCRKNFFLSKIRAHVATCSKYQNYIMEGVKATTKDASRQPRSVPNRYTFPCPYCPEKNFDQEGLVEHCKLSHSTDTKSVVCPICASMPWGDPNYRSANFIEHLQRRHQFSYDTFVDYDVDEEDMINQVLQRSIIDQ
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination of various substrates.  In turn, participates in the regulation of many biological processes including cell cycle, apoptosis, osteoclastogenesis as well as innate or adaptive immunity.  Acts as negative regulator of NF-kappa-B-dependent transcription by promoting the ubiquitination and stabilization of the NF-kappa-B inhibitor TNFAIP3.  May promote the ubiquitination of TRAF6 as well.  Acts also as a negative regulator of T-cell activation.  Inhibits cellular dsRNA responses and interferon production by targeting MAVS component for proteasomal degradation.  Ubiquitinates the CDK inhibitor CDKN1A leading to its degradationand probably also CDKN1B and CDKN1C.  This activity stimulates cell cycle G1-to-S phase transition and suppresses cellular senescence.  May play a role in spermatogenesis.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF114, RING finger protein 114, RING-type E3 ubiquitin transferase RNF114, Zinc finger protein 313.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GDI1_MAGO7
Sequence: MEEIAKEYDVIVLGTGLTECILSGVLSVKGKKVLHIDRNDHYGGEAASLNLQALFKKYGNYNSGEEPWAKYGRNTDWNIDLVPKFLMSSGELTNILVSTDVTRYLEFKQVAGSFVQQGSGPKATVAKVPSDAAEALRSPLMGIFEKRRMKSFIEWVGTFDLKDPATHKGLDLSSCTMKDVYDKFGLETGTKDFIGHAMALYLSDDYISKPGGAPEAIDRIRLYGNSVARYGKSPYIYPLFGLGDLPQGFARLSAIYGGTYMLNTNIDELLYEDGKAVGIKATMTGIEPEMKFETRAKMILGDPSYFSDKVKVVGHVLRAICVLKHPLAGTSDADSCQLIIPQSQVGRKNDIYIACVSSAHSVCPKGYYIAIVSTIAETSANHHLELQPGLERLGKIEEQFMGPPIPLYAPIEDGTSSGIFISKSYDATSHFETTTDDVKDIYRRATGEELKVEGLRDLQVAGDE
What is the function of this protein?
Regulates the GDP/GTP exchange reaction of YPT7 by inhibiting the dissociation of GDP from it, and the subsequent binding of GTP to YTP7.
What are the official names of this protein?
Rab GDP-dissociation inhibitor, Rab GDI.
What is the protein family that this protein belongs to?
Belongs to the Rab GDI family.
Protein: NANE_YERPB
Sequence: MSNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIQAVRRATDAPIIGIIKRDLPDSEVRITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRARATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQAIVPTEPDLALVTQLAQAGCRVIAEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: SYFB_SULTO
Sequence: MPTINIYKWRLLNELKISETQLEDLLFNLKSEMKPIDQDHIEIEINNDRPDLLFVYGIIRSIKGLLKKELGEPRYSVKDTDYVFEIKEVPSRPYALAAVVEDIKFDDELLKELIQFQEKLHITVGRKRKKIAIGLHDLKKIDSKHIIYTTVNLDYKFIPLNSDKEMSVREILESTPQGKEYGNISLLDGKMPAIMQDDGQILSLPPVINSEKTRINSKTQSLFIDVTGTSLDTVIFTLDVIVTNLAEMGGKIGRIKVISPYVDNSPLLQHKSIKITAEYINKILGTNLNKNEIIEYLKMARFDVNDLGKEIEVIIPPYRNDILSQIDITEEVAITYGYNNLSPTPYKIEKIGSLSDRTKLIRVLRDLSVGGGFTEIFTFTLISESLLLGDFVKILNPITVDYNSVRNSLLPSILIFLSKNQHARMPIRVFEIGDVVIRNENTETGYSNKLNAAYAIMNSRVSFEELQAPLHEILNSLGINPIYKRDTNPLFIEGRTASIYANNKKIGIIGEINPNILEKIDIEYPIVMSEIYLDEIKDIL
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTPRG_CHICK
Sequence: MRRLLQPCWWIFFLKITSSVLHDVVCFPALTEGYVGSLHESRHGSSVQIRRRKASGDPYWGYSGTYGPEHWVTSSEKCGGSHQSPIDIVDHQAHVLYEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDYFVSGAGLPGRFKAEKVEFHWGQSNGSAGSEHSINGKRFPVEMQIYFYNPDDFDSFGTAVLENREVGAMAVFFQVSQRDNSALDPIIRGLKGVVHHEKETFLDPFVLRDLLPTSLGSYYRYTGSLTTPPCSEIVEWIIFRKPVPISYHQLEAFYSIFTTEQQDHVKSVEYLRNNFRPQQRLNNRKVSKSAVKDAWSQDMTDILENPLGTEASKACSTPPVNMKVQPVNRTALLVTWNQPETIYHPPIMNYMISYSWTKNEDEKEKTFTKDSDKDLKAIISHVSPDILYLFRVQAVCRNEMRSDFSQTMLFQANTTRIFEGTRIVKTGVPTASPASSADMAPISSGSSTWTSSGLPFSFVSMATGMGPSSSGSQATVASVVTSTLLAGLGFSGSSISSFPSSVWPTRLPTAAAPTKQAGRPVVATTEPAAASPGPERDSALTKDGEGAEEGEKDEKSESEDGEREHEEEDEKEAEKKEKSRATAAAEARNSTEPSVATASPNWTAEEEGNKTVSGEEPNQNVVPKAGRPEEESFTDADTQPQPLPSTQVPPAFTDELYLEKIPRRPETTRKPLPKDNRFLEEYPSDNKFITINPADKNSSSMATRPSPGKMEWIIPLIVVSALTFVCLILLIAVLVYWRKCFQTAHFYVEDSSSPRVVPNESIPIIPIPDDMEAIPVKQFVKHISELYSNNQHGFSEDFEEVQRCTADMNITAEHSNHPDNKHKNRYINILAYDHSRVKLRPLPGKDSKHSDYINANYVSGYNKAKAYIATQGPLKSTFEDFWRMIWAQHTGIIVMITNLVEKGRRKCDQYWPTENSEEYGNIIVTLKSTNIHACYTVRPLHGQEHKDEKGSERKPKGRQNERTVIQYHYTQWPDMGVPEYALPVLTFVRRSSAARTPHMGPVVVHCSAGVGRTGTYIVIDSMLQQIKDKSTVNVLGFLKHIRTQRNYLVQTEEQYIFIHDALLEAILGKETEVSANQLHSYVNSILIPGIGGKTRLEKQFKLVTQCNAKYVECFSAQKDCNKEKNRNSSVVPSERARVGLAPLPGMKGTDYINASYIMGYYRSNENVITQHPLPHTTKDFWRMIWDHNAQIIVMLPDNQSLAEDEFVYWPSREESMNCEAFTVTLISKDRLCLSNEEQIIIHDFILEATQDDYVLEVRHFQCPKWPNPDAPISSTFELINVIKEEALTRDGPTIVHDEYGAVSAGTLCALTTLSQQLENENAVDVFQVAKMINLMRPGVFTDIEQYQFLYKAMLSLVSTKENGNGPMTLDKNGAVMASDESDPAESMESLV
What are the official names of this protein?
Receptor-type tyrosine-protein phosphatase gamma, Protein-tyrosine phosphatase gamma, R-PTP-gamma.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SCX8_CENNO
Sequence: KEGYIVNYYTGCKFACAKLGDNDYCLRECKARYGKGAGGYCYAFGCWCTHLYEQAVVWPLPKKKCRA
What is the function of this protein?
Beta toxin that binds site-4 of sodium channels (Nav), reduces peak current (observed on Nav1. 6/SCN8A (IC(50)=67. 7 nM), Nav1. 1/SCN1A, Nav1. 2/SCN2A, Nav1. 3/SCN3A (weak), Nav1. 4/SCN4A, and Nav1. 5/SCN5A), shifts the voltage of activation toward more negative potentials (observed on Nav1. 6, Nav1. 1, Nav1. 2, and Nav1. 4 (weak)), and induces resurgent currents at negative voltages following brief and strong depolarizations (observed on Nav1. 6, Nav1. 1 (weak), Nav1. 2 (weak), and Nav1. 3 (weak)) (PubMed:22200496).
What are the official names of this protein?
Beta-toxin Cn8, Toxin 8, Toxin II-13.4.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRF_GEODF
Sequence: MTRDEARAKIIFALDVNEFSDVEKWADLLSPHVGMFKVGKQLYTACGPAVVRMIQKYGGEVFLDLKYHDIPNTVAMASLEAARMGVKLFNLHALGGYEMMAKTVETLDKEFKGEERGKVLAVTILTSSNEQTLQEVGINLPVPEMVVKLAALAKKAGIDGVVASPQEVPLIREACGNDFLIVTPGVRPAFAAADDQKRIMTPAEAVKSGADYLVIGRPIAAAPNPAEAAQAIVAEIVAG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.