PharMolix/UniProtQA huggingface dataset:
Protein: ENO_SYNJB
Sequence: METAIEWITAHEILDSRGRPTLEALVGLANGATGLAQVPSGASTGTFEAHELRDGDPKRYGGKGVLRAVENILGPIQSELQGEDALNQARIDQLLIDLDGTPNKSRLGANAILAVSLATAKAAAEAVGLPLYKYLGGPFANLLPVPLMNVLNGGAHADNNVDIQEFMLVPIGAASFREALRYGAEVFAVLKQVLQQKGLSTGVGDEGGFAPDLDSNAAALDLLMTAIEQAGYKPGADIALALDVAANELLQDGQYHFEGKAHSAADMVAYYQQLLANYPILSIEDGLAEEDWAGWQAMTAQLGSRVQLVGDDLFVTNLTRLQKGIDSAAANAILIKPNQIGTLTETVSAIQLAVQAGFRTIISHRSGETEDTTIADLAVATRAGQIKTGSLCRSERIAKYNQLLRIEDELGEAAVYAGRVGLGPRAR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PURL_GEOTN
Sequence: MSLLLEPNAAMIKEQKLYREMGLTDEEFARIEAILGRLPNYTETGIFSVMWSEHCSYKNSKPVLKKFPTDGPHVLQGPGEGAGIVDIGDGLAVAFKIESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPIALLNSLRFGELTSPRVKYLFEHVVAGIAGYGNCIGIPTVGGEVQFDPAYEGNPLVNAMCVGIIRHEDIQRGVATGVGNTVMYVGAKTGRDGIHGATFASEELSEQSEAKRPAVQVGDPFMEKLLLEACLEAVKSDALVGIQDMGAAGLTSSSAEMASKGGFGIEMNLDLVPQRETGMTPYEMMLSESQERMLLVVEQGREEEIAAIFAKYGLEAKAIGKVTDDKMLRLFFHGEVVAEIPVDALAKDAPVYHKPSAEPDYYREFQAMPTYIPQIEDYNRTLLGLLAQPTIASKEWVYDQYDYMVRTNTVVAPGSDAAVVRIRGTNKALALTTDCNSRYLYLDPEMGGKIAVAEAARNVVCSGAKPLAITDCLNFGNPEKPDIFWQLEKAVDGMSEACRTLGTPVVSGNVSLYNETNGEAVYPTPVVGMVGLVDDLSHVTTQPFKQAGDLIYVIGEAKPEFGGSELQKWLEGRIFGKAPELDLAVEASRQRQLLTAIRAGVVASAHDVAEGGLAVALAECVIGASGLGANVTVSGDLVSELFSETQSRFVVSVKKEHQEAFEQLVEAKLIGEVTNDSILTVNGEHGGTVIRLSVDEMRNVWKGAIPCLLKSKD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_RALSO
Sequence: MIRLKAPTPERPLLLIDAGNTRIKWAWTAADVAPPAVAPGGTPWQHAGARPHDQLAELVEDWRDCHAGAGMAPPDVWISVVAGPALRDALCARIARVFDGARLRIVASEAAAAGLRNGYRDPAQLGTDRWVGAVGARHAWPDTALLLVTAGTATTLDIVAPDGRFAGGLILPGLTLMMRALSRNTAQLPEIDIGYLAARDDAQAPADVPSWADNTQDAIALGCVTAQAGAIAQTWQALQAQYPGPYRCVLSGGARAALAPHLRMPFQMHDNLVLLGLQVLAHTGHEGRPGAATQA
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CROB_LEPLU
Sequence: MPILGLGTWQAPPGKVEKAIKLDYLDLYLIHFPMGFKVIPSNTDIRDTWEGMEDLVDAGLVKYTSLIEDPXVKKIADKYNKEYPFHVDY
What are the official names of this protein?
Rho beta-crystallin.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: ALG13_YEAST
Sequence: MGIIEEKALFVTCGATVPFPKLVSCVLSDEFCQELIQYGFVRLIIQFGRNYSSEFEHLVQERGGQRESQKIPIDQFGCGDTARQYVLMNGKLKVIGFDFSTKMQSIIRDYSDLVISHAGTGSILDSLRLNKPLIVCVNDSLMDNHQQQIADKFVELGYVWSCAPTETGLIAGLRASQTEKLKPFPVSHNPSFERLLVETIYS
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway.
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG13, Asparagine-linked glycosylation protein 13.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
Protein: LEU1_POLSJ
Sequence: MTDKLIIFDTTLRDGEQSPGASMTKDEKLRIARQLERLKVDVIEAGFAASSNGDFEAVQAIANTIRDSTICSLSRANDRDISRAAEALKGANNARIHTFIATSALHMEKKLRMTPEQVLEQARLSVRFARNLVADVEFSPEDGYRSDVDYLCRVLEAVIDEGATTINVPDTVGYAVPELYGHFIKTLRERVPNSDKAIWSVHCHNDLGMAVANSLAGVMIGGARQVECTINGLGERAGNCSLEEIVMAVKTRKDYFNLEMNIDPLHIVAASRMVSQTTGFVVQPNKAVVGANAFAHASGIHQDGMLKARETYEIMRAEDVGWSASKMVLGKLSGRNAFKQRLQDLGVALESEADINTAFARFKELADRKSEIFDEDILALVSDESITHHDQEQYGFVSLAQHSETGERPHAVVVFTVAGKEIRGESDGNGPVDASLKAIETHVKSGAEMVLYSVNAISGSTESQGEVTVRLQNNGRVVNGVGADPDIVVASAKAYLSALNKLQSKADRVAAQG
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: AMIE_DELAS
Sequence: MRHGDISSSNDCVGVAVVNYKMPRLHTKAEVLDNCRKIADMLVGMKRGLPGMDLVIFPEYSTHGIMYDAKEMYDTASAIPGEETEIFADACRRANVWGVFSLTGERHEEHPNKAPYNTLILMNNQGEIVQKYRKIMPWVPIEGWYPGDCTYVSEGPKGLKISLIICDDGNYPEIWRDCAMRGAELVVRCQGYMYPAKEQQIMVSKAMAFMNNCYVAVANAAGFDGVYSYFGHSAIIGFDGRTLGETGEEEMGIQYAELSKHLIRDARKNGQSQNHLFKLVHRGYTGTINSGDGDKGVAACPYNFYSQWVNDPEGTREMVESFTRTTVGTPECPIEGIPHEAPKHR
What is the function of this protein?
Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates.
What are the official names of this protein?
Aliphatic amidase, Acylamide amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
Protein: CFAB_HUMAN
Sequence: MGSNLSPQLCLMPFILGLLSGGVTTTPWSLARPQGSCSLEGVEIKGGSFRLLQEGQALEYVCPSGFYPYPVQTRTCRSTGSWSTLKTQDQKTVRKAECRAIHCPRPHDFENGEYWPRSPYYNVSDEISFHCYDGYTLRGSANRTCQVNGRWSGQTAICDNGAGYCSNPGIPIGTRKVGSQYRLEDSVTYHCSRGLTLRGSQRRTCQEGGSWSGTEPSCQDSFMYDTPQEVAEAFLSSLTETIEGVDAEDGHGPGEQQKRKIVLDPSGSMNIYLVLDGSDSIGASNFTGAKKCLVNLIEKVASYGVKPRYGLVTYATYPKIWVKVSEADSSNADWVTKQLNEINYEDHKLKSGTNTKKALQAVYSMMSWPDDVPPEGWNRTRHVIILMTDGLHNMGGDPITVIDEIRDLLYIGKDRKNPREDYLDVYVFGVGPLVNQVNINALASKKDNEQHVFKVKDMENLEDVFYQMIDESQSLSLCGMVWEHRKGTDYHKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSIKVSVGGEKRDLEIEVVLFHPNYNINGKKEAGIPEFYDYDVALIKLKNKLKYGQTIRPICLPCTEGTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDAQYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWGVVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQDEDLGFL
What is the function of this protein?
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb.  Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase.  It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes.  Ba inhibits the proliferation of preactivated B-lymphocytes.
What are the official names of this protein?
Complement factor B, C3/C5 convertase, Glycine-rich beta glycoprotein, GBG, PBF2, Properdin factor B.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL25_HALH5
Sequence: MAMSLKAEKRPDLRGSVTRKIRKQGYVPAVVYGNKTKSQPISVEAVDFLKTVREVGRNGLISLEVEKGTKHQVMVHDLQMDPLKGDYLHIDFFEVDMSSEIEANVPVRLTGEARGVSEGGVLSQLMYEITVRSLPADIPEEITLDVSSLAIGDSIQIRDVRGNVPVQVVNEDEETVVTVQPPATEKEEETEAAVTDSEPEVINEKEEPAEEAKEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PMIP_NEOFI
Sequence: MKDQLLVPLRRRPWTCRKCLQRLQLLPQHQTRRSFETAASPFPRQLDSLPADYSRTKTVDDDTLRRVFDSQQFWREFSQQRSAQPKPTGLVQNQYLTSPDGFRTFANVSLQKCQAIVSKVLAASTLEEYRTMARDLDRLSDLLCRVIDLSDFIRVIHPDPQVQEAATQAYALMFEYMNVLNTTTGLNDQLKKAAANPEVTSQWSDEEKIVAQILIKDFSNSAIHMPPHERQRFVNLSNDISQLGSSFVNGAEPAKSHVSVATNNLRGLDPILVQQIKRWNRTAAVPTTGMIPRLALRSVHDENVRREVYLASRTSSKRQLHRLEELLLKRAELAKLSGYESFAHMTLSDKMAKSPEAVSNFLTALVDSNRKLVREELSQLQAMKGAPLQPWDHAYYVHQRVMQYSQARRSRELSAVPEFFSLGTVMQGLSRLFDRLYGVRLVPQEPAPGETWNPDVRRLDVVDESGRHIAVIYCDLFSRPNKHPNPAHFTLRCSREISTEEVAECASLDQSSHPNDGMATAVDPVTKTLRQLPTIALVCDFSEPGTNGGGRPSLLSEHSVRTLFHEMGHAVHSILGQTRLQSISGTRCATDFAELPSVLMEHFATAPSVLALYARHWRTDEPLSEGMIRSMERDRTAHGSIYGAVENEAQILMALVDQAYHSRPADGGRIDSTALYQQVSQQHSSLPEPADVTPPTSWQGFFGHLYGYGATYYSYIFDRAIANKLWVDVFGAGRQAVDRAAGERYKNEVLRWGGGRSGWECVAGALGSANESNADGRLVEGGDEAMREVGRWGLGRDGVSG
What is the function of this protein?
Cleaves proteins, imported into the mitochondrion, to their mature size.  While most mitochondrial precursor proteins are processed to the mature form in one step by mitochondrial processing peptidase (MPP), the sequential cleavage by MIP of an octapeptide after initial processing by MPP is a required step for a subgroup of nuclear-encoded precursor proteins destined for the matrix or the inner membrane (By similarity).
What are the official names of this protein?
Mitochondrial intermediate peptidase, MIP, Octapeptidyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TOP1_METJA
Sequence: MAEIMTALIICEKPSVAKKIANALGKAKKKSIDGVPYYELERDGKKIIVASAVGHLFTLVEKENKEFGFYPVFDIKWVPASVDKGKEYVNKYIKALKKLSKDADEFYIATDWDIEGELIGYHALKYCCGREKAKRMRFSSLTKKEIVRAFENPDEIDYGLVDAGESRHILDWYFGINLSRALMNAIRAVNRWKTMSVGRVQGPALAFLTERELEIKKFIPKPYWVIEALLKDNLKAIHEKEKFWNEKEAKNVYEKIKDEKSAKVVEIKKTKRKLKPLPPFDLGTLQREAYSYFKISPKETQEIAQKLYENALISYPRTSSQKLPKDRKYLEDILNIIKNHPVYGKWAERILKENLKPVEGKKEDPAHPAIHIVDIPKEELSEKEKEIYDLIARRTLAAFWDNAEREYLNVKIDIKGEKFKLSGSRTVKEGWHEIYYFPKFDEIELPPLKKNDIIKVEKITITRKETQPPKRYTVASIIKELEKRGLGTKATRAEIIDKLIKRGYVIDDGSLKVTDLGISVIETLKRFCPEIIDEKMTRDLEEKLEKIQFRKIKKDDVLDEAEKRLRKILEEFKKKEEDIGIYLIKNLDATNKKAKIVGKCPKCGGDLILIRHKKGRFVGCSNYPECDVKYSLPDKGRIKIPNKVCDACKSPILKIGDREICINPECPLKQVEVKEEDRICPKCGAKLILKKGVYGAFYGCSNYPKCKYTEPINKKEVVGKCPKCGGDLVVREGKFGKFVGCSNYPKCRYTEKLKLNEKEEK
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Omega-protein, Relaxing enzyme, Swivelase, Untwisting enzyme.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: SPEA_BACFR
Sequence: MRKWRIEDSEELYNITGWGTSYFGINDKGHVVVTPRKDGVAVDLKELVDELQLRDVAAPMLVRFPDILDNRIEKTAYCFKQASEEYGYKAQNFIIYPIKVNQMRPVVEEIISHGKKFNLGLEAGSKPELHAVIAVNTDSDSLIICNGYKDESYIELALLAQKMGKRIFLVVEKMNELKLIARMAKQLNVQPNIGIRIKLASSGSGKWEESGGDASKFGLTSSELLEALDFLESKGMKDCLKLIHFHIGSQVTKIRRIKTALREASQFYVQLHAMGFNVEFVDIGGGLGVDYDGTRSSSSESSVNYSIQEYVNDSISTLVDASDKNGIPHPNIITESGRALTAHHSVLIFEVLETATLPQWDDEEEIAPDAHELVQELYGIWDTLNQNKMLEAWHDAQQIREEALDLFSHGIVDLKTRAQIERLYWSITREINQIAGGLKHAPDEFRGLSKLLADKYFCNFSLFQSLPDSWAIDQIFPIMPIQRLDEKPDRSATLQDITCDSDGKIANFISTRNVAHYMPVHSLKQKEPYYVAVFLVGAYQEILGDMHNLFGDTNAVHVSVNEKGYNIEQIIDGETVAEVLDYVQYSPKKLVRTLETWVTKSVKEGKISVEEGKEFLSNYRSGLYGYTYLE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: GCS2_TRIV2
Sequence: MGDIEFKSSPEFSLGMEIELQLLNPDTLQLVDGISPLLAQTPENSWIQPEFNQAMVEIASQVCSNIPELEANIVAILRDLKTRCQALGMTICTAGTYPCCDRFASITPIPRYLSQQNTSGYLADLMMTCALQLHVGMPSGDVAIDIMGRLKPYLPILLALSASSPFWWGHDTSFASFRQRFLSSMRTYGICPTFKNWQDFTNFFATAQNAGMFEIIRDIHWDLRPQPDFGTLEVRVMDAQPTIKESMMLAAFIHSLIVDMYHHSQGKQTEFLLTPLPWLIERENYFRASRWGLDANYIEDEQGNSRPIRNIVKDILNVLAETADTLGNSSYLFQLEKRLDQGASYIRQRRVFESTGSVKAVVASLVSELEAELAIKSRQEAVAYGWL
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: SULA_ECOLU
Sequence: MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: KHSE_XYLFA
Sequence: MNRTLQPDRGASQTAPAAHQARAFAPASVANVAVGFDLLGYPMDQVGDTVTVRRIDTPQVRIAAIRGIAQPLPLQTERNTAGAALLSMHRDLALPFGFELEIDKGIPLSSGMGGSAASCVAALLAANALLEEPLRREHLYRYALDGEAVASGSRHGDNLGPLFLGGLVLCTLERLVPVTVPAAWHSLLVHPDTLLETRRAREVLKDPYLLPDIVTQSANLALVLAGCYHGDAELVRAGLRDVLIEPRRAPLIAGFTAAQQAALQADAMGASISGAGPSVFAWFQTRSAAEAAAPAVRAAFTAAGFDSQAWVTPLISPGARLL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEPA_BURMS
Sequence: MDHIRNFSIIAHIDHGKSTLADRIIQLCGGLSDREMESQVLDSMDLERERGITIKAQTAALTYRARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTAIELGVEVVPVLNKIDLPAANPENAIAEIEDVIGIDAMDAVRCSAKTGLGVEDVLESLIAKVPPPKGDPDAPLQALIIDSWFDNYVGVVMLVRIVNGTLRPKERIKLMATDAQYAVEHVGVFTPKSRNLESLSAGQVGFIISGIKELTAAKVGDTVTHATKPAPEPLPGFKEVKPQVFAGLYPVEANQYDALRESLEKLKLNDASLQYEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDMDLITTAPTVVYEVVQSDGTTIMVENPAKMPEPARIAEIREPIVTVNLYMPQDYVGSVITLCEQKRGTQINMQYHGRQVQLTYEIPMAEIVLDFFDRLKSVSRGYASMDYEFKEYRTSDVVKVDMLINGDKVDALSIIVHRSQSQYRGREVAAKMREIIPRQMYDVAIQAAIGAHIIARENIKALRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKQVGSVEIPQEAFLAILRVEDK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GSA_MICAN
Sequence: MVSTSSYQTTKSKEIFTAAQKLMPGGVSSPVRAFKSVGGQPIVFESVKGAYIRDVDGNEYIDYVGTWGPAICGHAHPEVIAALHDALDKGTSFGAPCVQENILAEMVIDAVPSIEMVRFVNSGTEACMSVLRLMRAFTGRDKIIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKTTTNNTLTAPYNDLEAVKALFVENPDSIAGVILEPVVGNAGFIVPDAGFLEGLRELTKEYGALLMFDEVMTGFRIAYGGAQEKFGITPDLTTLGKVIGGGLPVGAYGGRADIMAMVAPAGPMYQAGTLSGNPLAMTAGIKTLELLQRPGTYQYLDKVTKSLTEGLLKVARDAGHSVSGGYISAMFGMFFTGSPVHNYEDAKKADVAKFGRFHRGMLERGVYLAPSQFEAGFTSLAHTEADIERTLAAAKEVLASL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOI4_ARATH
Sequence: MSDKGRPLPKFGEWDVNDPASAEGFTVIFNKARDEKKTGGKPGSPGKSSEGHVKSGGGDPSKPQPKKWLCCMQAPAVDS
What are the official names of this protein?
Protein NOI4, Protein DiDi 18T-1d.
What is the protein family that this protein belongs to?
Belongs to the RIN4 family.
Protein: RL10_ECODH
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CYDX_ECOLI
Sequence: MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI
What is the function of this protein?
Required for correct functioning of cytochrome bd-I oxidase.  This protein and AppX may have some functional overlap.
What are the official names of this protein?
Cytochrome bd-I ubiquinol oxidase subunit X, Cytochrome bd-I oxidase subunit X, Cytochrome d ubiquinol oxidase subunit X.
What is the protein family that this protein belongs to?
Belongs to the cytochrome ubiquinol oxidase subunit X family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=In sucrose cushions fractionates with both the inner and outer membranes.
Protein: RUXF_YEAST
Sequence: MSESSDISAMQPVNPKPFLKGLVNHRVGVKLKFNSTEYRGTLVSTDNYFNLQLNEAEEFVAGVSHGTLGEIFIRCNNVLYIRELPN
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity).
What are the official names of this protein?
Small nuclear ribonucleoprotein F, snRNP-F, Sm protein F, Sm-F, SmF.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NSCD_TRIRC
Sequence: MTSIPIFESVSRFLPPANEDVQFWWKVTGRHMACMMHEAGYPEYRQVECLLFHRFKVIPCLGPRPHSDTPWYKSRVGGGAADGCPINYSWRFGTIERKPHIRNFIEPLGALTKTPADPLNEVATKALLQDYSMTLPNVDLEAFWTFAPHYRPRIIEKEDMEKLAGASLLVGAEMSPDSRTIDIKAYMYPRVPSQTSQLLTTILPQAMRDTYGEDVCLDSLNFVHDFMTNDPQGSQLALTGTTGIDCCKLQETRVKIYVITRNTSFDHIAAIMTLGGRRSISGELLGQLKALWYELKGAPAELPSSEQLPVQTKPDGSRNPIVVPFYFDIQPRLALPDVKAYIDVSTSPVSDLAAAKAVVRHLEQHGSGQNPKAYLNVLKDITPVEELETQKGALAFYSVAVKKNELDITSYFNPQVYKRYFAHEVQLNGQRRSVFE
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of neosartoricin B, a prenylated anthracenone that probably exhibits T-cell antiproliferative activity, suggestive of a physiological role as an immunosuppressive agent (PubMed:23758576).  The non-reducing polyketide synthase nscA probably synthesizes and cyclizes the decaketide backbone (By similarity).  The hydrolase nscB then mediates the product release through hydrolysis followed by spontaneous decarboxylation (By similarity).  The prenyltransferase nscD catalyzes the addition of the dimethylallyl group to the aromatic C5 (By similarity).  The FAD-dependent monooxygenase nscC is then responsible for the stereospecific hydroxylation at C2 (By similarity).  Neosartoricin B can be converted into two additional compounds neosartoricins C and D (By similarity).  Neosartoricin C is a spirocyclic compound that is cyclized through the attack of C3 hydroxyl on C14, followed by dehydration (By similarity).  On the other hand, neosartoricin D is a further cyclized compound in which attack of C2 on C14 in neosartoricin C results in the formation of the acetal-containing dioxabicyclo-octanone ring (By similarity).  Both of these compounds are novel and possibly represent related metabolites of the gene cluster (By similarity).
What are the official names of this protein?
Prenyltransferase nscD, Neosartoricin B biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: VPE_VICSA
Sequence: MGSSQLSTLLFFTIVVTFLTVVSSGRDLPGDYLRLPSETSRFFREPKNDDDFEGTRWAILLAGSNGYWNYRHQSDVCHAYQLLRKGGSKEENIIVFMYDDIASNEENPRPGVIINKPDGDDVYAGVPKDYTGAEVHADNFYAALLGNKSALTGGSGKVVDSGPNDHIFVYYTDHGGPGVLGMPVGPYLYASDLNEVLKKKHASGTYKSLVFYLEACESGSIFEGLLPDDLNIYATTASNAEESSWGYYCPGDKPPPPPEYSTCLGDLYSIAWMEDSEVHNLQTESLQQQYKLVKNRTISEPYGSHVMEYGDIGLSKNDLYQYLGTNPANDNNSFVDETENSLKLRTPSAAVNQRDADLIHFWEKFRKAPEGSSQKNEAEKQVLEAMSHRKHIDNSVKLIGQLLFGIEKGTELLDVVRPAGSPLVDNWDCLKTMVKTFETHCGSLSQYGMKHMRSFANICNAGIPNEPMAEASAQACASIPANPWSSLQGGFSA
What is the function of this protein?
Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms.
What are the official names of this protein?
Vacuolar-processing enzyme, VPE, Proteinase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: RS6_BORAP
Sequence: MIKRYEACFLFKSEEIEYKGSLEEVKKSLELYGATDIISNFIGERALEYPIKKQARGRYEIIEFSMEGNNLKEFESKLKLIKSLLRYMILVKIVRKINTKKIKRRNFREFKDNIDKENLKSGSKIEVPTSSESADIQEK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.