PharMolix/UniProtQA huggingface dataset:
Protein: AMPP1_AJECH
Sequence: MGPIDTSQRLARLRELMQERKVDVYVVPSEDSHQSEYIAHCDGRREFISGFTGSAGCAIVSMTKAALSTDGRYFNQAAKQLDNNWILLKRGFENMPTWQEWTAEQAEGGKVVGVDPSLITASDARNLSETIKKCGGSLLGVQENLVDLVWGAERPARPSEKVALHPIEFAGKSFEEKISDLRKELQKKKCAGFVISMLDEIAWLFNLRGNDIPYNPVFFAYAIITQSTADLYIDEEKLPAEVKNYLGDKVSLKPYSSIFEDAKVLGQSAQNKSDGETSTKPPQKFLISTRASWSLSLALGGEKNVEEVRSPITDAKAIKNEAELEGMRACHIRDGAALSEYFAWLENELVNKKTVLNEVDASDKLEQIRSKHQHFVGLSFDTISSTGPNAAVIHYKAERNNCSIIDPKAVYLCDSGAQYLDGTTDTTRTLHFGEPTEMEKKAYTLVLKGLISIDTAVFPKGTTGFALDAFARQYLWKEGLDYLHGTGHGVGSYLNVHEGPIGLGTRVQYSEVAIAPGNVISDEPGYYEDGVFGIRIESPFFPHLLINLPFLLTPIIDIIMAKEVKTTHKFGEKPWLGFEHVTMTPLCQKLINPSLLSDVEKKWVNDYHTEIWEKTSKYFENDELTRNWLKRETQPI
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase P, AMPP, Aminopeptidase P, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: TPT1L_HUMAN
Sequence: METVIMITYWDLISHSEMFSDSYMSQEIADGLRLEVEGKIVSRTEGNIFDSLIGGNASAEGPEGKGTESTVITGVDSVMNHHLQETSFTKEAYNKCIKDYMKSIKGKLEEQRPKRVKPFMTGAAEQIKHILANFKNYQKT
What are the official names of this protein?
TPT1-like protein.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
Protein: DNAT_KLEP3
Sequence: MSSRILTSHFSGLEEFLQQHAALLAKSTDGTVAVFANNAPAFYALTPARLAQLLELEARLARPGSDIALAPQFFEEPAAAPVAVPMGKFAMYADWQPDADFQRLAALWGIALSQPVTPEELAAFVAYWQAEGKVFHHVQWQQKLARSVQISRASNGGQPKRDVNSVSEPDSHIPRGFRG
What is the function of this protein?
This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response.  It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'.
What are the official names of this protein?
Primosomal protein 1, Primosomal protein I.
What is the protein family that this protein belongs to?
Belongs to the DnaT family.
Protein: MNMC_HAEIN
Sequence: MTFSVQHAEIHFNQNHIPVSDQFDDVYFSNENGLAETDYVFLQGNQLWERWITHKDANFVIAETGFGTGLNFFAVTKLFREFRQQHENHPLKRLNFISFEKYPLKITALLQAHLACPQFEDLSAHLQRYWPSLILGCHRIHFGETTLDLWFGDVSENLPQLGDYMNERINAWFLDGFAPSKNPEMWNDDLYNLMFRFTKPNGTFATFTAASAVRKGLESAGFNVTKRKGFGKKRECLSGLKIQSKSTALSTPWYLAQPAKMEKQDVAIIGGGIASLCAAISLIKRGAKVTIYCEDDALALNASGNKQGAFYPQLSDDNALTVDFYLHAFSYGRQLLDWAIEQNIVFEHEFCGVALCAYNEKSAVKLTKISQLGLPNEIFQMLSAEQLSEKVGLPLNCEGGWIEQGAWLAPRQFVQNAFSFLEKQGVVIKTAQKITALSQLEKGWELKNMQGQKYCHEVVILANGHKITDFVQTEKLPLYPIRGQVSQIPTSENLLKLKSVLCYDGYLTPANQLKTSHCIGASMFRDNVDRDFSEQEQQENQQKLQQNIAQPWTQDVDTSDNLARVGIRCSVRDLAPMVGNVPHFEQQQADYYNLFNLRRRKQPIQSAANFQNLFLIAALGSRGLTSAPLLGETLASIIYGEPLPISEGILHNLSANRAWVKKWLKGSKVE
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPB_RICPU
Sequence: MIRFITIPDFADYQVILKLMEDYVNKVISDHEPEIIYLVEHSEVYTAGTNYKQEELLNYGDIPVIYTGRGGKFTFHGPGQRVIYPILNLDSPNRHKDLKLYIKMLEEWIINSLNYFGIKAYIIKDKVGIWVKVRKDEFAKIAAIGVRVRKWVTYHGVAINISTDLSKFSGIIPCGLEDSLVTSLNQLGIHVEMSEFDKIIQTEFNKIFK
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AZOR_GEOKA
Sequence: MTKVLYITAHPHDDTQSYSMAVGKAFIETYKQVHPDHEVIHLDLYKEYIPEIDVDVFSGWGKLRSGKSFEELSDEEKAKVGRMNELCEQFISADKYVFVTPMWNFSFPPVLKAYIDAVAVAGKTFKYTEQGPVGLLTDKKALHIQARGGFYSEGPAAEMEMGHRYLSVIMQFFGVPSFEGLFVEGHAAVPEKAEEIKANAIARAKDLAHTF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: NADE_STRPQ
Sequence: MTLQEEIIRQLGVKASIAPQEEIRKTVDFLKAYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAELREETSDQAYQFIAVRLPYGVQTDEADAQKALAFIMPDQTLTINIKAAVDGQVEALQAAGVEISDFNKGNIKARQRMISQYAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: BGLL_NEOFI
Sequence: MQNLFLSLLAAAVTVHAYGSGGSNWDQAYSRAKDALQKLSQTEKVGLVTGVKWMGGPCVGNTYKPESIDYPSLCLQDSPLGIRFANPVTAFPAGINAGATWDTQLLYARGAAMGAEAKGLGVHVQLGPVAGPLGKNPNGGRNWEGFSVDPYLSGVAMEKTIRGMQDSGVQACAKHWLGNEQEHYRDTISSNIGDRAAHELYVWPFMDAVKADVASVMCSYNKVNGTWACESDAINNKLMKEELGFPGYIMSDWNAQHSTVNSAVSGLDMTMPGSDFSNPPGSIFWGSNLEAAVADGSVPQSRLDDMVTRILAAWYLVGQDKGYPPVAFSSWNGGKANVDVTADHGTVARAVARDSIVLLKNDQRTLPLRKPKSLAIVGLDAIVNPAGPNACSDRGCNNGTLAMGWGSGTAEFPYLVGPLDAIQKRAAADGTKIVPSTTDDPTAGASAAAAAETAIVFINSDSGEGYITVEGNLGDRNNLDPWHNGNELVKAVAAASKNVIVVVHSVGPIILETILAQPSVKAIVWAGLPGQESGNALVDVIYGDTAPSGKLPYTIAKQAADYGASWINAETDDFTEGLYIDYRHFDAKGIAPRYEFGYGLSYTTFKYSGLWVNVYTSAGAANGKVVPGGPADLFEVVGQVSVFVRNNGRVAGAEVAQLYIGLPDSAPATPPKQLRGFQKMMLQPGQMGRATFELTRRDLSYWDVQQQKWVVPSGTFKVYVGSSSRDIREEGSFRVRRGW
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase L, Beta-D-glucoside glucohydrolase L, Cellobiase L, Gentiobiase L.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLIE_OCEIH
Sequence: MTISIMGNNVTPIQPNESVNQVKRSPSEAQANFASTLKNAIEDLNHIQLESDKKTEAFASGKIDDLHDVMITAQKSSVTLETTVQVQKKVIDAYNEIMRMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: CCND1_CANLF
Sequence: MAHQLLCCEVETIRRAYPDANLLNDRVLRAMLKAEETCAPSVSYFKCVQKEILPSMRKIVATWMLEVCEEQKCEEEVFPLAMNYLNRFLSLEPVKKSRLQLLGATCMFVASKMKETIPLTAEKLCIYTDNSIRPDELLQMELLLVNKLKWNLAAMTPHDFIEHFLSKMPVAEENKQIIRKHAQTFVALCATDVKFISNPPSMVAAGSVVAAVQGLHLGSSNSFLSYHRLTRFLSKVIKCDADCLRACQEQIEALLESSLRQAQQQSLDPKAAEEEEEEEEADLACTPTDVRDVNI
What is the function of this protein?
Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.  Also a substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity.  Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.  Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner.
What are the official names of this protein?
G1/S-specific cyclin-D1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus membrane. Note=Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members.
Protein: RK36_CAPBU
Sequence: MKIRASVRKICEKCRLIRRRGRIRVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR4_GLACO
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKNKQRSKALIQNFIASSPHQEELPNHLTIDPFQYKGLVNQIIDSKWIGLKIN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: URE3_SYNPV
Sequence: MHLSPQEKDKLLIVTAALLAERRLNRGLKLNHPEAVAWLSFLVLEGARDGKSVAELMQEGTTWLSRNQVMDGIPELVQEVQIEAVFPDGTKLVTLHDPIR
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRR3_HUMAN
Sequence: MVLAFQLVSFTYIWIILKPNVCAASNIKMTHQRCSSSMKQTCKQETRMKKDDSTKARPQKYEQLLHIEDNDFAMRPGFGGSPVPVGIDVHVESIDSISETNMDFTMTFYLRHYWKDERLSFPSTANKSMTFDHRLTRKIWVPDIFFVHSKRSFIHDTTMENIMLRVHPDGNVLLSLRITVSAMCFMDFSRFPLDTQNCSLELESYAYNEDDLMLYWKHGNKSLNTEEHMSLSQFFIEDFSASSGLAFYSSTGWYNRLFINFVLRRHVFFFVLQTYFPAILMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITAVSASMPQVSYLKAVDVYLWVSSLFVFLSVIEYAAVNYLTTVEERKQFKKTGKISRMYNIDAVQAMAFDGCYHDSEIDMDQTSLSLNSEDFMRRKSICSPSTDSSRIKRRKSLGGHVGRIILENNHVIDTYSRILFPIVYILFNLFYWGVYV
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit rho-3, GABA(A) receptor subunit rho-3, GABA(C) receptor.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR3 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: CRYAB_PIG
Sequence: MDIAIHHPWIRRPFFPFHSPSRLFDQFFGEHLLESDLFPASTSLSPFYFRPPSFLRAPSWIDTGLSEMRLEKDRFSVNLDVKHFSPEELKVKVLGDVIEVHGKHEERQDEHGFISREFHRKYRIPADVDPLTITSSLSSDGVLTVNGPRRQASGPERTIPITREEKPAVTAAPKK
What is the function of this protein?
May contribute to the transparency and refractive index of the lens.  Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.  In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity).
What are the official names of this protein?
Alpha-crystallin B chain, Alpha(B)-crystallin.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Secreted. Lysosome. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. Localizes at the Z-bands and the intercalated disk in cardiomyocytes. Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: Y2338_SALRD
Sequence: MYRVPIHEWDESDQPREKLLTHGPTVLSDAEVLALLLGSGTRTSDGPVSAVELGRALLQSYGSLHEVSQRKPKELTRTRGVGPAKATKLAAAFEAGRRVESQRQQDERMQVTCPADVADVYGPLLRDLDKEVFKVVHLNTANVIIGDYTVSEGGLSSSVVEPRGVFEQAILDDAAAVICLHNHPSGNPEPSREDIRITRQLAEAGGTMGIPVHDHLIIAGTKHTSLAERGVID
What are the official names of this protein?
UPF0758 protein SRU_2338.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: YV004_HUMAN
Sequence: MPSTEGFGGLDRLVLPPPPQVLPLLSPARGRIQFSGRKSTGSWVTQMENLLLAQPLPDDCEILCGWRSLLHLTFLIGFAPHFPHWFCNHHCHQHPPSHLTEVLQSSGELAHQLAPSRCSMRAEGTHRG
What are the official names of this protein?
Putative uncharacterized protein FLJ23865.
Protein: SPEB_ENT38
Sequence: MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPNEGLIDPNHSVQIGIRTEFDKDNGFTVLDAGQVNDRGVDDIIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: S39AC_XENTR
Sequence: MFKWKKSLFWRIPVFFTFGALFVCAESRHKDNKQPPSQGGLLQALYSLNSANGTFLHKNNSTDIISLLLEKVECPKNVHGKQDPCTQCLRPDALLFMVGINKSSDIDDDAIQKISVVLLFYIMNQKDFCTSISNLTKMDYKFYRNSLLKLRKDEDCHYLSLNEIDDILSVSKQYFQLLEEKQCTDVISMEDAFAMVGSTAVDEIKLPRLAEIILTLSLQRVCITRKQFPNAEFFTDFIFQSFNRTNDLYAPDIAELIGELKATGDCSKLSNRRKSVRSVIPQKDNELLSNTNEEKGHDHSDIYEVEAHSRYWHQTHSCFSVYELVKVFFKNSHSPVSKEQFKQISPAIIHQLLTCSCPPASNGTTRLAPPTTLEKYGYSTISVLLLTIGSMFGATLIIFSSCEENYKLILQLFVGLAVGTLSGDALLHLIPQVLGVHEVVTHEHHMQQGDYIFEENEYLWKIMGMIGGIYGFFLINKLFFLLVSSPKQGLSLMNGHLTHSHDLPLDAHLGDQSRKAKSSSTIQLRSPDDCEHSEVPETLPVRPKARRKSKGISLLAIMILVGDSLHNFADGMVIGSAFSSSTETGIASTVAILCHEIPHEMGDFAVLLNTGLSAKIAFLMNFISALTAFAGLYIGLSLSANPDVQIWIFAVTAGMFLYLSLVEMLPEMIHVQTQRPWLMFFLQNLGLLLGWLCLLLLAIYEHKIQF
What is the function of this protein?
Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane.  The transport activity is temperature dependent (By similarity).  May play a role in neurulation and neurite extension (By similarity) (PubMed:23716681).
What are the official names of this protein?
Zinc transporter ZIP12, Solute carrier family 39 member 12, Zrt- and Irt-like protein 12, ZIP-12.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
Protein: KARG_TRYCR
Sequence: MASAEVVSKLEAAFAKLQNASDCHSLLKKYLTKEVFDQLKGKQTKMGATLMDVIQSGVENLDSGIGVYAPDAESYTLFAALFDPIIEDYHKGFKPSDKQPPKDFGDLNTFIDVDPDKKYVISTRVRCGRSLEGYPFNPCLKKQQYEEMESRVKGQLESMSGELRGKYYPLTGMTKETQKQLIDDHFLFKEGDRFLQAAHACKFWPTGRGIYHNDAKTFLVWVNEEDHLRIISMQKGGNLKEVFGRLVTAVGVIEEKVKFSRDDRLGFLTFCPTNLGTTIRASVHIKLPKLGADRKKLEEVAAKYNLQVRGTAGEHSDSPDGVYDISNKRRLGLSEYEAVKEMQDGILELIKAEESAR
What are the official names of this protein?
Arginine kinase, AK.
What is the protein family that this protein belongs to?
Belongs to the ATP:guanido phosphotransferase family.
Protein: RIMM_PELPD
Sequence: MIDSESLIPVGKLVATHGIRGMLKLHSYSGSVESLCTCDSVILRSRDGALNRFEPKPVLPRPGKFLIGFKGVDHIDQAQTLVGSEICLRRDQLPEPEEDEYYWCDLIGLEVATVEGMALGVLEEIFKAGSSDIYVVRGAGREYLIPAIADVIHSVDLEMGRMLITPLEGLLDL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYAY_PSEA7
Sequence: MNEVRFHDLVDAVQQQVEDAFDDSGLDLDLENAGGVLTVRFENGSQLILSRQAPLYQLWVAAKSGGFHFDYDETSGLWRHDASREPLGALLNRATLEQGGEDVEFPGL
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: F3GT1_RHODL
Sequence: MTKNISRDRHVAVLPFPFSSHAGRLLTLVRRLAAAAPNVTFSFYSTPKSIESLFSPAERVPGNVRPYAVPDGVPEGHVFSGEPVEHVNLYLTAVGEGESLRGVLKAAEAETGRRIGCVMSDAFMWFAGDLAEEMGVPWVPFMAGGANSITAHFYTDLIRETVGMHDIVGRENDIVKFIPGFSELRLGDLPTGVLFGNLESPFAIMLHKMGRALPKATAIAINSFEELDPDIIQDLKSKFKMILNVSPFSAISLPSSPPPPPTSYTDEYGCMPWLDNRKAASVAYIGFGTLATPPPVEIAALAEALEASGTPFLWSLKDNPKEFFPEGFIKRTSERQKIVPWAPQEQVLAHGSVGVFVTHCGWNSALESIAAGVPLIGRPFFGDHQLNAWLVENVWKIGVRVEGGVFTKSGTMSALELVLTHEKQKELRARVEMFKKLALKAVGPEQSSTRNLHTLLEIVAGYNL
What is the function of this protein?
Flavonoid 3-O-glycosyltransferase involved in the biosynthesis of anthocyanins confering flower red/pink colors, mainly anthocyanidin 3-O-glycosides (PubMed:35651780).  Catalyzes the addition of UDP-sugar to the 3-OH of anthocyanidin, with a preference for UDP-galactose (UDP-Gal) as sugar donor and cyanidin as substrate; able to use delphinidin, pelargonidin, peonidin, malvidin and petunidin as substrates in the presence of UDP-Gal (PubMed:35651780).  Can also use UDP-glucose (UDP-Glu) as sugar donor with delphinidin, cyanidin and malvidin as substrates, but not active on pelargonidin, peonidin and petunidin (PubMed:35651780).
What are the official names of this protein?
Anthocyanidin 3-O-galactosyltransferase 3GT1, Flavonoid 3-O-glycosyltransferase 1, Rd3GT1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PITX2_CHICK
Sequence: MSCMKDPLSLERLGAGNNKLCSSSPSSSSSSSSCHHQQPALAMATALAPGQARSSLEAAKHRLEVHTISDTSSPEAAEKEKSQQGKSEDAGPEDPSKKKRQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGPQFNGLMQPYDDMYPGYSYNNWAAKGLTSASLSTKSFPFFNSMNVNPLSSQSMFSPPNSISSMSMSSSMVPSAVTGVPGSGLNSLNNLNNLSNPSLNSAVPTPACPYAPPTPPYVYRDTCNSSLASLRLKAKQHSSFGYASVQNPASNLSACQYPVDRPV
What is the function of this protein?
May play an important role in development and maintenance of anterior structures.  May play a role in determining left-right asymmetry and in vasculogenesis during avian embryogenesis.
What are the official names of this protein?
Pituitary homeobox 2, Homeobox protein PITX2, cPITX2, Paired-like homeodomain transcription factor 2.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS1_GEOKA
Sequence: MLTIAMPKGRIFEEAVELLRRADYALPPEFTESRKLVIDVPEENMRFILAKPMDVVTYVEHGVADLGIAGKDVLMEEERDVYELLDLHISRCHLAVAGMPGAKMNEIAPRVATKYPNIASTYFREQGEQVEIIRLNGSIELAPLIGLADRIVDIVSTGRTLRENGLVELERIAEVTSRLIVNPASYRLNGGDIERLVDRLAAVIPQP
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_MYCBO
Sequence: MSELIVNVINGPNLGRLGRREPAVYGGTTHDELVALIEREAAELGLKAVVRQSDSEAQLLDWIHQAADAAEPVILNAGGLTHTSVALRDACAELSAPLIEVHISNVHAREEFRRHSYLSPIATGVIVGLGIQGYLLALRYLAEHVGT
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: IOLA_LISMF
Sequence: MADVRKLKNYINGEWVESRADKYEDVINPATGEVLCQVPISTRAELDQAAVIAEQAFEKWSQVAVPRRARVLFSFQQLLIQHKEKLARLITLENGKNLSEARGEVQRGIENVEFAAGAPTLMMGDSLASIATDVEAANYRYPVGVVGGIAPFNFPMMVPCWMFPMAIALGNSFILKPSERTPLLMEKLVELFSEAGLPKGVFNVVYGAHDVVNGILENEIIKAVSFVGSKPVGEYVYKTGSANLKRVQALTGAKNHTIVLNDADLEDTVTNVISAAFGSAGERCMACAVVTVEEGIADEFLAALRTAAQNVKIGNGLDDGVFLGPVIREENQKRTIAYIEKGLEEGAKLTVDGRETGLSEGHFVGPTILEDVTTDMTIWKDEIFAPVLSVIRVKNLQEAVRVANQSEFANGACIFTNNAKAIRYFREKIDAGMLGVNLGVPAPMAFFPFSGWKSSFYGTLHANGKDSVDFYTHKKVVTARYSLKGYEE
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase, MSA dehydrogenase, Methylmalonate-semialdehyde dehydrogenase, MMSA dehydrogenase, MSDH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: AL7A1_MOUSE
Sequence: MWRVPRRLCVQSVKTSKLSGPWSRPAAHMSTLLIHHPQYAWLQDLGLREDNEGVYNGSWGGRGEVITTYCPANNEPIARVRQASLKDYEETIGKAKKAWNIWADIPAPKRGEIVRKIGDAFREKIQLLGRLVSLEMGKILVEGIGEVQEYVDVCDYAAGLSRMIGGPTLPSERPGHALIEMWNPLGLVGIITAFNFPVAVFGWNNAIALITGNVCLWKGAPTTSLVSVAVTKIIAQVLEDNLLPGAICSLVCGGADIGTTMARDERVNLLSFTGSTQVGKEVALMVQERFGKSLLELGGNNAIIAFEDADLSLVVPSVLFAAVGTAGQRCTTVRRLFLHESIHNEVVDRLRSAYSQIRVGNPWDPNILYGPLHTKQAVSMFVRAVEEAKKQGGTVVYGGKVMDHPGNYVEPTIVTGLAHDAPIVHQETFAPILYVFKFQDEEEVFEWNNEVKQGLSSSIFTKDLGRIFRWLGPKGSDCGIVNVNIPTSGAEIGGAFGGEKHTGGGRESGSDAWKQYMRRSTCTINYSTSLPLAQGIKFQ
What is the function of this protein?
Multifunctional enzyme mediating important protective effects.  Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor.  Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes.  Involved in lysine catabolism.
What are the official names of this protein?
Alpha-aminoadipic semialdehyde dehydrogenase, Alpha-AASA dehydrogenase, Aldehyde dehydrogenase family 7 member A1, Antiquitin-1, Betaine aldehyde dehydrogenase, Delta1-piperideine-6-carboxylate dehydrogenase, P6c dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasm, cytosol. Nucleus. SUBCELLULAR LOCATION: [Isoform 2]: Mitochondrion.
Protein: DGTL1_MYCTO
Sequence: MSASEHDPYDDFDRQRRVAEAPKTAGLPGTEGQYRSDFARDRARVLHSAALRRLADKTQVVGPREGDTPRTRLTHSLEVAQIGRGMAIGLGCDLDLVELAGLAHDIGHPPYGHNGERALDEVAASHGGFEGNAQNFRILTSLEPKVVDAQGLSAGLNLTRASLDAVTKYPWMRADGLGSQRRKFGFYDDDRESAVWVRQGAPPERACLEAQVMDWADDVAYSVHDVEDGVVSERIDLRVLAAEEDAAALARLGEREFSRVSADELMAAARRLSRLPVVAAVGKYDATLSASVALKRLTSELVGRFASAAIATTRAAAGPGPLVRFRADLQVPDLVRAEVAVLKILALQFIMSDPRHLETQARQRERIHRVAHRLYSGAPQTLDPVYAAAFNTAADDAARLRVVVDQIASYTEGRLERIDADQLGVSRNALD
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.