PharMolix/UniProtQA huggingface dataset:
Protein: RL24_SULNB
Sequence: MATKFKIKKGDQVMVIAGDDKGKTGEVLQVLPKKEAVIVAGCKMAKKAIKPSEQNKEGGFANAEMPIHISNVKKVEA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS3_LISMO
Sequence: MGQKVHPIGMRIGVIRDWDSKWYAEKDYADFLHEDLRIRDYVAKRLSDASVSRVEIERAANRVNITIHTAKPGMVIGKGGSEVEALRKNLNELTQKRVHINIVEIKRADLDAKLVAENIARQLEGRVSFRRAQKQAIQRTMRAGAKGIKTQVSGRLGGADIARAEHYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPTKKNNVEGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: CORZ_PACBA
Sequence: QTFQYSRGWTN
What is the function of this protein?
Cardioactive peptide.  Corazonin is probably involved in the physiological regulation of the heart beat (By similarity).
What are the official names of this protein?
Corazonin.
What is the protein family that this protein belongs to?
Belongs to the corazonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y406_METEP
Sequence: MRPPADPGARRRATHGRGLSAEGLALLVLMLKGYRPLARRFAAAGGEIDLIVRRGRTIAFVEVKARATLDAAATAIDARKRARVSRAARAWLARHPLAAGATLRADAVFVAPRRWPRHLPNAFEIEGL
What are the official names of this protein?
UPF0102 protein Mext_0406.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: IFP1_CAEEL
Sequence: MDSANARDCLLHLARAKLSERQDLVQLNDQFVDIIEHVHYMEAEHTALEHDYNLLKSGVQSDSSGINEIYNVEIRTVRSGIEEINRSRHELLNEQTQLSHQVKEAEQLWRHTAKSALGVPKEVDDEFHRICHIKMEDCITKRRIKYMEDKLRLIKQNNGRIFEHINLMRMRKDQAVSLQQEYLLRKNELLHSIRNMEEDNKKIIMNEHKYFVRDRNADRHVFRDQLRKAIADIRADYEANRLRNEEEIRIRLEREIHRMNTTMPGVVCYDKLREELSIVKNNLSGLQKQVSEVEIRNNSLTQQIEFYRLEISENNKLFEDTLEFKIKEIEKMREQCTAISVELEKLCDLNIDLQKEIAKYRELLDRSGDPRANAPSTQVIASALSRQNYSSISDHHSRTSSGIVQHTAHHAVRDSSSSRTGTTIHETITHTPIPIPATLPVQPIREYTYSRDASPIRPSYTPYQQESRADSRSSLRERIQIETLQGTLPVLPSHSVETIRASDNTRLVRDLSAGGQINTTQINNPYASRTPTSSVNDRIASERRDSEIRRNDALHQPYPIGGAVPRVEPTIFNERAPGYTHINSNFPLITPVTEGATVPSYYDTFNRNSSQRGPHHSSYHAATGSVSNSISTTLLNEGSIEHSSSSDSVDEDNFQRFTRWYKGRVKISDVTADFVQLVNRSSKKSADVGGFKLIHEFGNKSVYVDLPVGLILAPKDSLKIYARGATHERGAVIAEIDFFDTTIHTNTSIRNTNNEVKSWFVYTSNTEIGDADHHHH
What is the function of this protein?
Cytoplasmic intermediate filaments provide mechanical strength to cells.  Not essential protein.
What are the official names of this protein?
Intermediate filament protein ifp-1, Cel IF E1, Intermediate filament protein E1, IF-E1.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31_MYCMM
Sequence: MKSDIHPTYEETTVVCGCGNTFQTRSTKQGGRIVAEVCSQCHPFYTGKQKILDSGGRVARFERRYGKRKAGADKDQAAADK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PG040_VAR67
Sequence: MIVLLILSLACTAFTYRLQGFTNAGIVAYKNIQDGNEDDNIVFSPFGYSFSMFMSLLPASGNTKVELLKTMDLRKIDLGPAFTELISGLAKPKTSKYTYTDLTYQSFVDNTVCIKPSYYQQYHRFGLYRLNFRRDAVNKINSIVERRSGMSNVVDSTMLDNNTLWAIINTIYFKGTWQYPFDITKTHNTSFTNKYGTKTVPMMSVVTKLQGNTITIDDEEYDMVRLQYKDANISMYLAIGDNMTHFTDSIMAAKLDYWSSQLGNKVYNLKLPRFSIENKRDIKSIAEMMAPSMFNPDNASFKHMTRDPLYIYKMFQNAKIDVNEQGTVAEASTIMVATVRSSPEELEFNTPFVFIIRHDITGFILFMGKVESP
What is the function of this protein?
Prevents cell to cell fusion via its interaction with A56 protein.  The A56-K2 complex associates with components of the entry fusion complex (EFC) presumably to avoid superinfection and syncytium formation (By similarity).
What are the official names of this protein?
Superinfection exclusion protein, Protein K2, Serine proteinase inhibitor 3.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Orthopoxvirus OPG040 subfamily.
Protein: YACG_BRADU
Sequence: MDDQVKMPTGPLKTCPICGKPAVQATHPFCSSRCRDVDLNRWLKGSYVIPGRDDEVDDVE
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: ARGD_STAES
Sequence: MSYLFNNYKRDNIEFVDANQNELIDKDNNVYLDFSSGIGVTNLGFNMEIYQAVYNQLNLIWHSPNLYLSSIQEEVAQKLIGQRDYLAFFCNSGTEANEAAIKLARKATGKSEIIAFKKSFHGRTYGAMSATGQKKITDQFGPVVPGFKFAIFNDFNSFKSLTSNNTAAVIIEIIQGESGVLPADPLFMKQLNEYCKQKDILIIVDEVQTGIGRTGKLYAHEHYQLSPDIITLAKGLGNGLPIGAMLGKKNLGHAFGYGSHGTTFGGNRLSLAAANQTLSIINDADLLNDVQSKGQFLIENLRKSLVNKRNVIEVRGVGLMVGIEVTNDPSQVVREAKRMGLIILTAGKNVIRLLPPLTITKKQLEKGIEILTEII
What are the official names of this protein?
Acetylornithine aminotransferase, ACOAT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BACP2
Sequence: MKKIGLFGGTFDPPHNGHLLMANEVRFQVGLDEIWFIPNHKPPHKTDRKRADSRHRVKMVEAAIESNPHFRLELIEMEREGPSYTVDTVELLKKRHPEDEFFFMIGADMVEYLPKWHRIDDLLQMITFIGMKRPGYTGSTTYSLLFADVPAFDVSSTLIRQRIMQEKPVDYLLPKAVERYIKEHHLYES
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: SOTB_ECOL6
Sequence: MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAHSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LRR1_ORYSI
Sequence: MGAGALGVVAMVAAAVVVAMAGANSEGDALSALRRSLRDPGGVLQSWDPTLVNPCTWFHVTCDRDNRVTRLDLGNLNLSGHLVPELGKLDHLQYLELYKNNIQGTIPSELGNLKNLISLDLYKNNISGTIPPTLGKLTSLVFLRLNGNRLTGPIPRELAGISSLKVVDVSSNDLCGTIPTSGPFEHIPLSNFEKNPRLEGPELQGLAVYDTNC
What is the function of this protein?
Involved in plant defense response.
What are the official names of this protein?
Leucine-rich repeat protein 1, OsLRR1.
What are the subcellular locations of this protein?
Early endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Protein: TUSA_SHIFL
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_ACIET
Sequence: MTKHRVVVGLSGGVDSAVTAHLLKQQGHEVVGIFMKNWEDDDDSEFCSSRQDFLDAASVADVIGIEIEHVNFAAEYKDRVFAEFLREYQAGRTPNPDVLCNAEIKFKAFLDHAMRLGAEKIATGHYARVRQNPATGLFELLKGLDPSKDQSYFLHRLNQAQLSKTLFPVGDLHKTEVRRIAADIGLPNAKKKDSTGICFIGERPFREFLNRYIQHAPGPILDDRGRKLGRHVGLSFYTLGQRQGLGIGGVKEKGAQRGAGDHAPWFVARKELETNTLRVVQGHEHPWLLSHRLDAQDASWIAGHPPAAGACAAKTRYRQQDAACTVLAAQGDAFSLQFPEAQWAVTPGQSAVLYDGEVCLGGGVIAAVNG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_PASMU
Sequence: MPRRRSIEPRKILPDPKFGSELLAKFINVLMVDGKKSIAEKIVYSALDTLAQRTGKEALEAFEAALDNVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALGMRWIVDAARKRGDKSMALRLANELSDASENKGAAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PLSY_PSEAB
Sequence: MVWLLAILAYLLGSLSFAVLLSRWFGTQDPRASGSGNPGATNMLRVAGKKLAILTLLGDVGKGLLPVLVARWLGLGVMEEAWVGIAAVIGHLYPLYFNFRGGKGVATAAGMLLGLYPPAVLLAAAAWLLTFKLSRTSSLASLVATPLTLPLLAWQQPGALLPMTVLTGLIVWRHRANLRDLFAGRERHF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RD3L_HUMAN
Sequence: MPLFGWMKWPKNDSYKPTHYPGSDIVTKTLLRELKWHLKERERLIQEIENEQKVKKTGVDYNWLRNYQNPHTTIPVTEQRQLEVLCSQVQPCQTGTILSRFREVLAENDVLPWEIVYIFKQVLKDFLSSSDRGSEQEDLEDSGSMDCSAPSVIQGDSSKRADKDEIPTISSYVDKNTKDRFPVFSHRIWNLPYYHPSS
What are the official names of this protein?
Protein RD3-like, Retinal degeneration protein 3-like.
Protein: BIOB_METCA
Sequence: MTNQERAEEPVLRHDWTQGEAEALFALPFNELLFQAQTIHRRHFDPNEVQVSSLLSIKTGACSEDCAYCPQSAHYETGVKRESLMSLEDVLEAAQRAREEGATRFCMGAAWRSPRDGDLEAIAAMVEGVKALGMETCVTAGMLSDEQARRLKEAGLDYYNHNLDTSESYYGEIITTRTYQDRLDTLQRVRDAGMHVCCGGIVGMGESAADRAGLLIGLANLPRHPESVPINLLVRVEGTPLADTAALDPFDFVRTVAVARIMMPASRVRLSAGRSDMSDEMQALCFLAGANSIFYGDRLLTTENPQAQRDRRLFARLGLRMAGLGC
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: Y273_STRP8
Sequence: MSILEINNLHVSIEGKEILKGVNLTLKTGEVAAIMGPNGTGKSTLSAAIMGNPNYEVTQGQILLDGVNILDLEVDERARLGLFLAMQYPSEIPGITNAEFMRAAMNADKADEDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGKDFGAMIITHYQRLLNYITPDLVHVMMDGRIVLSGDAALATRLEKEGYAGIAQDLGIEYKEES
What are the official names of this protein?
Probable ABC transporter ATP-binding protein spyM18_0273.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ycf16 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: WHIB2_MYCSM
Sequence: MSYESGDFDRVVRFDNRLLGSVSHAPHIDTGSTPTGAAGRPQLSLVPDSFDVAPEAEEDQWQERALCAQTDPEAFFPEKGGSTREAKRICQGCEVRDACLEYALAHDERFGIWGGLSERERRRLKRGII
What is the function of this protein?
Acts as a transcriptional regulator.  Probably redox-responsive.  The apo- but not holo-form probably binds DNA (By similarity).  Affects the localization or efficiency of septum formation.  Complemented by whiB2 of M. tuberculosis and whiB of S. coelicolor.
What are the official names of this protein?
Transcriptional regulator WhiB2.
What is the protein family that this protein belongs to?
Belongs to the WhiB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_EHRCR
Sequence: MHTPVLLNEMLDILNPQDGKVYVDATFGAGGYTRAILKSANCQVYAIDQDECTNVFYEKLVNDFPGKVHFCVSKFSKIKQILHGAQLKKVDGIVFDIGVSSMQLEDASRGFSFSKDGPLDMRMSTSISNVDASVFVNTAFEEEIANVIYQYGGEKYSRKIAKAIAESRKKKPIKTTGELASIVRSVISRSKNHSIDPATRTFQAIRIWVNKELEELEQGIIDSADLLNPGGKIIVVSFHSLEDRIVKVMFKSLCSGSSVISPIGFQLINKKVIRPSFEEILNNPRSRSAKLRAILKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL59_CAEEL
Sequence: MFSITRRLLSKNWKFLPNRERIVFKNKKEAFFDFVKVSGANILWQIGLAVLVLEFAFPTPDIVYDLKRLISPDFDLFCKSGNLVDFEMDFENKLRSIRREEIRSLEQYTNAKSPEAKFGGII
What are the official names of this protein?
Uncharacterized protein F44E2.9.
Protein: CYB_LANLU
Sequence: MALNLRKNHPIMKTINDALIDLPTPSNISIWWNFGSLLGICLIMQITTGLLLAMHYTADTSLAFSSVAHICRDVQFGWLIRNLHANGASFFFICIYLHIGRGLYYGSYMNKETWNIGIILLLMLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFLIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYSIKDILGFALMLILLARLALFSPNMLGDPENFAPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASILVLFLIPLLHKSKQRSMTFRPLSQILFWALVANILILTWVGSQPVEHPFIIIGQLASFSYFLILLVLFPIASVLENKMLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ENGB_LAWIP
Sequence: MMTQYKLQLEATNFTKQQLQQQLDILEQNNILQIALAGRSNVGKSSLINALAGRKQLAKTSGTPGKTRSINFYAVYPNTFMLVDLPGYGYAQCSKIERQHWAMLIEYYLKNCSKLKAFVLLIDCRIPPQKLDYELAEFATSYCIPLIPVLTKIDKCKLVEQNKRQKEWRALLNNTQPLLVSSKNMKGVQQLWERIQYTIDSY
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CUTC_ECOSM
Sequence: MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVDMPRMEKIMAAAGPLAVTFHRAFDMCANPLNTLNNLAELGITRVLTSGQKSDALQGLSKIMELIAHGDAPIIMAGAGIRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDAHADEYSRYVVDGAAVAEMKGIIERHQAK
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDAS1_HUMAN
Sequence: MAFPGQSDTKMQWPEVPALPLLSSLCMAMVRKSSALGKEVGRRSEGNGDAGGPFPAVKFPIKDIQFSESGEGTRFLHGARLSPLSRNIKARLLLYVRASPLFYESRITLKKPSNRHEVKRNRCNRKTAKQMLMTTLFNELEPTRKYGITEDCTSLNRVLFSANRKCLHKSLYKKDCFKAAPFSMFSFR
What are the official names of this protein?
Uncharacterized protein IDI2-AS1, IDI2 antisense RNA 1, IDI2 antisense gene protein 1.
Protein: RS20_SYNE7
Sequence: MANIKSAIKRVQIAERNRLRNKAYKSAVKTLVKHCFTAFDAYAADPNETARQAVNERLSAAYSKIDKAVKRGVLHANTGARKKARLAKAFHLKVDPQA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: KDM8_SALSA
Sequence: MAELWSAISAALPVTEAEFPLDFSEKVEPSVVDVLKRCRQQLYTGSGRWRQNAQIILDFSWEKLNTGTWRDVDKEWRCLYSYGCLFKVAALCRDDASPATVQEAIRTCDLGLLMGAAIMDNILQTFVKILQNEIRKRHSNEENLSEGVSAKKMKVDCVSVPVVKQALAVPRIHCPSLESFKKDYLDPQKPVILEGIIDHWPAFKNHPWSIEYLQTVAGCRTVPVEVGSRYTDEEWSQTLLTVNEFIDRYIVVKDASSLGYLAQHQLFDQVPELKDDIRIPDYCCLGEGEEDDITINAWFGPGGTVSPLHQDPQQNFLAQVVGRKYIRLYSPEDTEKLYPHQLQLLHNTSQVEVESPDVVRFPEFVKAPYLECVLQPGEVLFIPVKHWHYVRSLELSFSVSFWWS
What is the function of this protein?
Histone demethylase required for G2/M phase cell cycle progression (By similarity).  Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator (By similarity).  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 8, JmjC domain-containing protein 5, Jumonji domain-containing protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASSY_SINMW
Sequence: MASHKDVKKVVLAYSGGLDTSIILKWLQTELGAEVVTFTADLGQGEELEPARKKAEMLGIKEIYIEDVREEFVKDFVFPMFRANAVYEGVYLLGTSIARPLISKHLIDIARKTGADAIAHGATGKGNDQVRFELSAYALNPDIKIIAPWRDWSFKSRTDLLEFAEKHQIPVAKDKKGEAPFSVDANLLHSSSEGKVLEDPAQEAPEYVHMRTISPEAAPDKATIIKVGFERGDAVSIDGVRMSAATLLAKLNEYGRDNGIGRLDLVENRFVGMKSRGVYETPGGTILLSAHRAIESITLDRGAAHLKDELMPRYAELIYYGFWFSPEREMLQAAIDKSQEHVEGEVTLKLYKGNVMVVGRESGKSLYSDKLVTFEDDQGAYDQKDAAGFIKLNALRLRTLAARNR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_SALTI
Sequence: MSSRIDRDVINALIAGHFADPFSVLGMHQTQAGLEVRALLPDATDVWVIEPKTGRKVGKLECLDARGFFCGVLPRRKNFFRYQLAVTWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKFELLDANGNLRIKADPYAFEAQMRPETASMICGLPEKVTPSEERQKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPVNEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFINAAHAAGLNVILDWVPGHFPSDEFSLAEFDGTHLYEHSDPREGYHQDWNTLIYNYGRREVSNYLVGNALYWMERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRIIGEQVPGAVSMAEESTDFSGVTRPPETGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLTFGMLYNHTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKALHELDFDAYGFEWLVVDDNERSVLIFVRRDKAGNEIIVASNFTPVPRHDYRFGINQPGRWREILNTDSMHYHGSNTGNGGVVHSDEIESHGRQHSLNLTLPPLATIWLMREGE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: RL6_AZOSB
Sequence: MSRVAKNPVVIPKGVEVSISAAEIAIKGPLGTLVRPQHPAVTVEQDGEALVCKARDGQVNARAMSGTVRALLNNMVVGVSKGFERKLLLVGVGYRAQAQGDKLNLSLGFSHPVVHQMPAGVKVETPSQTEIVIKGVDKQQVGQVAAEVRAYRAPEPYKGKGVRYSDEVVVLKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RS12_BURM9
Sequence: MPTINQLVRKGRASETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRRQARSKYGAKRAKAAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: ASSY_LARHH
Sequence: MHEVKKVVLAYSGGLDTSVILKWLQDTYQCEVVTFTADIGQGEEVEPARKKALALGIKPENIFIDDLREEFVRDFVFPMFRANAVYEGEYLLGTSIARPLIAKRQIEIANMVGAEAVSHGATGKGNDQVRFELGYYALKPEVKVIAPWREWDLLSREKLLAYAETHGIDISKRKSGASPYSMDANLLHISYEGLALENPAAEPEEDMWLWSNSPEAAPDEAEYIELEYSQGDIVAVNGMAMSPAQVLTRLNQLGGKHGIGRLDIVENRYVGMKSRGCYETPGGTIMLKAHRAIESITLDREVAHLKDELMPKYAKLIYTGYWWAPERRMLQAMIDESQKTVNGWVRLKLYKGNVIVVGRESKTDSLFDPAIATFDEDGGAYNHADAAGFIRLNALRMRIAANARQRRG
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG1_YARLI
Sequence: MKAWHWSVTLVVIYLAIPVILYLLTRKDDRKPLSDIRKRKRTIVLVLGDLGRSPRMLYHARSLARSGHKVDLCGYDGAKPFDEILNNDLIKIHHIPLILNTRKLPFVVFGILKVIRQHWLLISLLYKLRGADYLLVQNPPSIPTLGVVRFYNLFLSTRTKVVLDWHNFGYTILALKLPETHPMVKFAKFYEGFFGGRAFVHLCVTVLMGQAMRKTFGMSGRRIVPLHDRPAFHFKPLSESEKLDVLRDFKETLYDDMTADHKIIVSSTSYTPDENFNILLDALALYDESKLDLPPLRVIITGKGPMMPEFLAKVEKLQLKRVSIRTAWLEFADYPRILGAAHLGVSLHESSSGYDLPMKVVDMFGCGIPVVSVDYAALSELVKTNTNGVAVKGHVEMGNTFMSLFSNRGKLDNIKRGAMIESRNTWDQTWVKTVGPLFDIGEYVQQRPDEDYDFSSSSSDDDH
What is the function of this protein?
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation.  Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity).
What are the official names of this protein?
Chitobiosyldiphosphodolichol beta-mannosyltransferase, Asparagine-linked glycosylation protein 1, Beta-1,4-mannosyltransferase, GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase, GDP-mannose-dolichol diphosphochitobiose mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.