PharMolix/UniProtQA huggingface dataset:
Protein: BAP1_RAT
Sequence: MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNSMFFAHQLIPNSCATHALLSVLLNCSNVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRVKYEARLHVLKGNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKPASSKSPFGLEAGRTPAASECTHTDGAEEVAGSCPQTTTHSPPSKSKLVVKPSGSSLNGVPPTPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPQQYSDDEEDYEDEEEDVQNTSSAIRYKRKGTGKPGSLSNSSDGQLSVLQPNTINVLTEKLQESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSTRSSQGSQGSSSLEEKEVVEVTDSRDKSGLNRSSEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRRKRSRPYKAKRQ
What is the function of this protein?
Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1.  Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).  Does not deubiquitinate monoubiquitinated histone H2B.  Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains.  Deubiquitination of HCFC1 does not lead to increase stability of HCFC1.  Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination.  It however does not mediate deubiquitination of BRCA1 and BARD1.  Able to mediate autodeubiquitination via intramolecular interactions to couteract monoubiquitination at the nuclear localization signal (NLS), thereby protecting it from cytoplasmic sequestration.  Acts as a tumor suppressor.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase BAP1, BRCA1-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C12 family. BAP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly nuclear. Binds to chromatin. Localizes to the cytoplasm when monoubiquitinated by the E2/E3 hybrid ubiquitin-protein ligase UBE2O.
Protein: RNC_STRPQ
Sequence: MKQLEELLSTSFDIQFNDLTLLETAFTHTSYANEHRLLNVSHNERLEFLGDAVLQLIISEYLFAKYPKKTEGDMSKLRSMIVREESLAGFSRFCSFDAYIKLGKGEEKSGGRRRDTILGDLFEAFLGALLLDKGIDAVRRFLKQVMIPQVEKGNFERVKDYKTCLQEFLQTKGDVAIDYQVISEKGPAHAKQFEVSIVVNGAVLSKGLGKSKKLAEQDAAKNALAQLSEV
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACON_RAT
Sequence: MAPYSLLVTRLQKALGVRQYHVASALCQRAKVAMSHFEPSEYIRYDLLEKNINIVRKRLNRPLTLSEKIVYGHLDDPANQEIERGKTYLRLRPDRVAMQDATAQMAMLQFISSGLPKVAVPSTIHCDHLIEAQLGGEKDLRRAKDINQEVYNFLATAGAKYGVGFWRPGSGIIHQIILENYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGTLSGWTSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMKKYLSKTGRADIANLAEEFKDHLVPDPGCQYDQVIEINLNELKPHINGPFTPDLAHPVADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSEQIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRSDFDPGQDTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPVDKLTIQGLKDFAPGKPLNCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKELQQ
What is the function of this protein?
Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
What are the official names of this protein?
Aconitate hydratase, mitochondrial, Aconitase, Citrate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CHR35_ARATH
Sequence: MGFVYIVMTGYYKNVHKRKQNQVDDGPEAKRVKSSAKVIDYSNPFAVSNMLEALDSGKFGSVSKELEEIADMRMDLVKRSIWLYPSLAYTVFEAEKTMDNQQVVEGVINLDDDDDDDTDVEKKALCVVPSSSEIVLLDSDDEDNERQRPMYQFQSTLVQHQKNQGDVTPLIPQCSFEEVDLGRGKEMPSAIKAIVEGQTSRGKVLPIENGVVNEKGVYVGVEEDDSDNESEAADEDLGNIWNEMALSIECSKDVARETSHKEKADVVEDCEHSFILKDDMGYVCRVCGVIEKSILEIIDVQFTKAKRNTRTYASETRTKRFGESDNELKFSEEGLMIGGLAAHPTHAAEMKPHQIEGFQFLCSNLVADDPGGCIMAHAPGSGKTFMIISFMQSFLAKYPQAKPLVVLPKGILPTWKKEFVRWQVEDIPLLDFYSAKAENRAQQLSILKQWMEKKSILFLGYQQFSTIVCDDTTDSLSCQEILLKVPSILILDEGHTPRNEDTNLLQSLAQVQTPRKVVLSGTLYQNHVKEVFNILNLVRPKFLKLDTSKSAVKRILAYTPCDVRGRLTGSNSDMASMFNETVEHTLQKSEDFTVKIKVIQDLREMTKKVLHYYKGDFLDELPGLADFTVVLNLSPKQLNEVKKLRREKRKFKVSAVGSAIYLHPKLKVFSDKSDDVSDTTMDEMVEKLDLNEGVKAKFFLNLINLCDSAGEKLLVFSQYLIPLKFLERLAALAKGWKLGKEVFVLTGNTSSEQREWSMETFNSSPDAKIFFGSIKACGEGISLVGASRILILDVPLNPSVTRQAIGRAFRPGQKKMVHAYRLIAGSSPEEEDHNTCFKKEVISKMWFEWNEYCGYQNFEVETIDVDEAGDTFLESPALREDIRVLYKR
What is the function of this protein?
Subunit of the chromatin-remodeling complex (DDR complex) that mediates RNA polymerases IV and V (Pol IV and Pol V) recruitment to chromatin (PubMed:19013275, PubMed:22864289).  Cooperates with Pol IV and Pol V to regulates RNA- and RNAi- (RNA interference) directed non-CpG de novo DNA methylation on cytosine of genes targeted for silencing and enhancers, also known as siRNA-directed DNA methylation (RdDM), thus leading to epigenetic modification of the genome and promoting/maintaining heterochromatin (PubMed:15120073, PubMed:15947783, PubMed:15924141, PubMed:16724114, PubMed:16741558, PubMed:19204117, PubMed:19825647, PubMed:22647529, PubMed:18425128).  In collaboration with Pol V, mediates/maintains, in cis, methylation-associated self-silencing of exogenous transgene transcribing inverted-repeat (exo-IR) silencer (exo-Pdsi) to restrain exo-IR dsRNA accumulation and subsequent inappropriate silencing of active protein-coding genes (e. g.  PDS) by exo-IR-derivating 24-nt siRNAs (PubMed:21771120).  Also required to mediate loss of CpG methylation when the silencing inducer is withdrawn (PubMed:15947783).  Required for the maintenance of retrotransposon large terminal repeats (LTRs) and transposable elements (TE) edges silencing mediated by cytosine methylation (PubMed:16724114, PubMed:23540698).  Required for transcriptional repression of specific classes of pericentromeric 180-bp repeats by promoting condensation and histone H3 lysine 9 dimethylation (H3K9me2) at chromocenters (PubMed:19825650).  Required for basal resistance against the necrotrophic fungal pathogen Plectosphaerella cucumerina (PubMed:22242006).
What are the official names of this protein?
Protein CHROMATIN REMODELING 35, Protein DEFECTIVE IN MERISTEM SILENCING 1, Protein DEFECTIVE IN RNA-DIRECTED DNA METHYLATION 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family.
Protein: FPRS3_MOUSE
Sequence: MEANSSIPLNGSEVVFYDSTTSRVLWILSVIVLSITFVLGVLGNGLVIWVAGFRMAHTVTTICYLNLALGDFSFMVTLPLHIISMVMKGKWLFGWFLCKFVLSIVHINLFVSVFLITLIAMDRCTCVLHPVWVQNHRTVSLARKVIVGAWILSLLLTLPHFLFLTTVRDARGEVHCTCNFESVVANPEEQLKVSITVSTATGIISFIIGFSLPMSFIAVCYGLMAAKICRKGFLNSSRPLRVLTAVAISFFMCWFPFQLIILLGNIWNKETPSSIHILLNPASTLASFNSCLNPILYVFLGQEFREKLIYSLSASLERALREDSVLSSGKSSNFSSCPADSEL
What is the function of this protein?
May have an olfactory function associated with the identification of pathogens or of pathogenic states.
What are the official names of this protein?
Formyl peptide receptor-related sequence 3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TIG_BACC4
Sequence: MSTKWEKLEGNVGVLTIEVDAKEVNNSIDAAFKKVVKTINVPGFRKGKMPRPLFEQRFGIESLYQDALDIILPKAYGEAIEEAGIFPVDHPEIDIEKFEKNANLIFTAKVTVKPEVKLGEYKGLAVEKVETTVTDEDVENELKSLQERQAELVVKEEGTVENGDTAVIDFEGFVDGEAFEGGKGENYSLAIGSGTFIPGFEEQVIGLKSGESKDVEVSFPEEYHAAELAGKPATFKVTIHEIKTKELPELNDEFAKEADEAVATLDELKAKLRTNLEEGKKHEAEHKVRDEVVELAAANAEIEIPEAMINTELDRMVREFEQRLSQQGMNLELYYQFTGTDADKLKEQMKEDAQKRVRINLVLEAIIEAENIEVTEEEVTAEVEKMAEMYGMPVDAIKQALGSVDALAEDLKVRKAVDFLVENAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: RAD9A_HUMAN
Sequence: MKCLVTGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG
What is the function of this protein?
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair.  The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex.  Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER).  The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates.  The 9-1-1 complex is necessary for the recruitment of RHNO1 to sites of double-stranded breaks (DSB) occurring during the S phase.  RAD9A possesses 3'->5' double stranded DNA exonuclease activity.  Its phosphorylation by PRKCD may be required for the formation of the 9-1-1 complex.
What are the official names of this protein?
Cell cycle checkpoint control protein RAD9A, hRAD9, DNA repair exonuclease rad9 homolog A.
What is the protein family that this protein belongs to?
Belongs to the rad9 family.
Protein: OTSA_KLEP7
Sequence: MSRLVVVSNRIALPDDKKSSAGGLAVGILGALRAAGGLWFGWSGEIGDDQQPLKQVSRGNISWASFNLNERDHDEYYNQFSNAVLWPAFHYRLDLVSFQREAWEGYLRVNAMLADKLLPLIEPDDTLWIHDYHLLPFASELRKRGVNNRIGFFLHIPFPTPEIFNALPPHAELLEQLCDYDLLGFQTESDRTAFLDSIAMQTRLSDLGDKRYQAWGKAFSTEVYPIGIDPDEITRNAKGPLPPKLAQLKNELKNVKNIFSVERLDYSKGLPERFLAYETLLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLETAAGRINGQFGQLGWTPLYYLNQHFDRKLLMKVFRYSDVGLVTPLRDGMNLVAKEYVAAQDPDNPGVLVLSQFAGAAQELTSALIVNPYDRDEVAAALDRALSMPLAERIARHSAMLDVIRENDIHNWQARFVEDLQHISPRSEESRLRGKIATFPKLA
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: RL36_RUTMC
Sequence: MKVRASVKKICNNCKIIKRHGVVRVICKEPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: TYSY_OCEIH
Sequence: MLGEQAYLDLCKQIFKTGEQRGDRTNTGTHSIFGHQIRFDLNKGFPLLTTKRVPFRLVASELLWFIKGDTNIRYLLKHNNNIWNEWAFEKWVNSADYQGPDMANFGLRSQKDENFNKQYQEQMELFKTRILEDDSFADKYGDLGSVYGKQWRNWKTTQNETIDQLKDVIHSIKTNPNSRRHIVSAWNPEDIPTMALPPCHTLFQFYVSNGKLSCQLYQRSADVFLGVPFNIASYALLTHLIAHECGLEVGDFVHTFGDAHIYSNHVEQVETQLEREIRDFPQLIINKDKNSIFEMDLDDLVIENYNPHPSIKAPIAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_XANC5
Sequence: MRRKIVAGNWKLHGSRAFATELVAKVAAHMPLEGVEVVILPPLPYLGDLIEDFEAHHLSFGAQDVSSNEKGAYTGEVSASMLVDVGAGYGLVGHSERRQYHHESSELVARKFAAAIHAGLIPVLCVGESLEQREAGQTEAILRAQLDPVLALVGSAGFAGAVLAYEPIWAIGTGRTATPEQAQAVHAFLRGEVAKADARIADSLPILYGGSVKPDNAGELFAQPDVDGGLVGGASLVAEDFLAIARAAAAC
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_STRP4
Sequence: MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAETAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSPDIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRLAELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDKVIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFSGKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVAESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALKEAVK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_METST
Sequence: MSKLFISCALPYANGPCHLGHLRSTYIPADIYARYNRMTGVDTLMVCSTDEHGTPIAVRAEQEKKNPKDITDIYHEIIGNDLKSCNISLDSFRRTTDEIHYKMAQDFFLDLYNKGYIYEKVIDQLYCDECKRSLPDRYVEGTCPYCESEGARGDQCEVCGRHLNPTDLVEPHCLICDSTPHIEQSKQYYFKLHEFEQPLKEWINSNEHLPKNVKNFAKEWLNDGLKDWIMTRDMNWGIPVPLNDAEGKVLYVWAEAFEGYQSSAASWANKHDLDWKEYWDDKTVHFIGKDIIYHHTLFWPSMLMGRGWNLPYSVVGGGYLSLEGRKMSTSKGWVIWVEDFLKKFDSDLLRYYMVINAPLNKDTDFSWDDFQRRVNNELTDNLGNFIHRTFTFTNKFFDGKIPEMGSYTDEDKEFEEKIKALPDVVANYIDNFQFREGLQGIMSLTKEANKYFNDKKPWKGVKEDIESAKTCINLSNQLVHVLSIVLTPYIPISVQKIRKVLNMPTEHVDGFMKFEERTPLVKWDEAKEFLPAGYEINSAKPLFSKIPDEIIKEEKDKLYSLEEENKENEDDNMSDLISIDEFGKVKLVVGQIKEAQKIDGSENLLKLQVDLGKEVRQVVAGIAKRYEVDELIDKKVIVVANLQPAKLFGVESNGMLLATDSMELLTTEGNVGEYIK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_METNO
Sequence: MRFPSPLTEGRLVRRYKRFLADVELADGRVVTAHCANPGTMLGLIAPGRPVLLSASTNPARKLAWSWEMVQADLPGGPQWVGINTLRPNLLVAEAFREGRLPPLSGAATLRPEVRYGRASRVDFLAEGPAGPCHVEVKNCHMMREAGLAEFPDCVAARSARHMDELADVVRGGGRALLIVVVQMRAARFDVAGDIDPGFAAAFRRARAAGVETVAYACRLDPDEVTIDREIPIVTA
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: UPPP_YERPN
Sequence: MTDMYSLFVAFILGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGAVPHEGKTNGHLTLGHILLAMIPAVILGLAFHDVIKALFDPKSVMYALVAGGVLLLAAEWLKPKNPKAVGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTLGDLPMFAVGFITAFIVALIAIKTFLSLIKRISFVPFAIYRFIVAAVVYWVFM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAC_STRP1
Sequence: MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVIPANMQTIIDETIAEQLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEYEFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHFESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKILLPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: ISPG1_STRAW
Sequence: MTAISLGMPSVPTKLAERRKSRQIQVGTVAVGGDAPVSVQSMTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALAVIARKSQIPVIADIHFQPKYVFAAIEAGCAAVRVNPGNIKQFDDKVKEIAKAAKEHGTPIRIGVNAGSLDRRLLEKYGKATPEALVESALWEASLFEEHDFRDIKISVKHNDPVVMVNAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPVEEIKVGIQILESLNLRQRGLEIVSCPSCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEIIKTVPESKIVETLIEEAMKIAEQMEADGIASGEPSVSVAG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) 1, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: Y359_RICPR
Sequence: MKLLQIIFIITIYINLHIFVLAENLESVEDSENDVFIPLDKNHPILNQKDNIYSAEFKNYTNGKIIALNKITATSEEIGLKAGEEKYFGNIKIKLHKCIKNLDPYNQDNYLLMTITEYKIDEDPTLLFQGWMVSSSISLSTFEHPIYEIFAKDCF
What are the official names of this protein?
Uncharacterized protein RP359.
Protein: PA2A_BOTFO
Sequence: NLWQFGMMIQHTTRENPLFKYFSYGCYCGWGGGGPLDATDRCCFVHDCCYG
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that impairs hemostasis.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Basic phospholipase A2 Bfon11, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_ECODH
Sequence: MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS11_SULDN
Sequence: MAKRKAVRKKVVKKNIARGICHISASFNNTLVTITDEMGNMIAWSSAGSLGFKGSKKSTPFAAQAAVEDAVAKAQVHGVKELGIKVQGPGSGRETATKAVGGIEGIRVTFMKDVTPLPHNGCRAPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RL36_STAAS
Sequence: MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: IPL1_DEBHA
Sequence: MYCRVFTHFSLYRLYTLSDNININKTNHNKSIGLHQHRVNYMPRSMTASSSQLKRIETRIESLSESLSKSNARKPLGKFQLNTFDNNKITKLQNEKVRPSKSSHIPVKSPIRKKGHSPAQVLQNERMDTKLLLQKLPSASRHMTLDDFEIGKVLGKGKLGKVYCVKHKTSGYIAALKVMAKKDLIDLKLEKNFRREIEIQSNLIHPKISRLYGFFYDHKNVYLILEYSIHGELYHHLKVQRRFNDATASHYIYQVALALDYLHTKHIIHRDIKPENILLSTDNCIKLSDFGWSVKSSPSSSTKRLTICGTLDYLPPEMIESNEHDYTVDIWSLGILCYEFLVGKPPFEEIDKNSTYKRIAKVDLKIPSFLSSEATDLILRLLQKSPKKRITLAEVMNHPWIMNNQQYWPNEN
What is the function of this protein?
Required for high-fidelity chromosome segregation during the later part of each cell cycle.  Acts in opposition to the phosphatase PP1.  Has a role in attaching the kinetochores to the microtubules and ensuring that sister kinetochores connect to opposite poles.  The promotion of bi-orientation is achieved by selectively detaching kinetochore-microtubule attachments that are not under tension.  Phosphorylates histone H3 to form H3S10ph during mitosis and meiosis (By similarity).
What are the official names of this protein?
Spindle assembly checkpoint kinase, Aurora kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Note=Associates with the mitotic spindle and on elongated and disassembling spindles. Also associated with the kinetochore (By similarity).
Protein: LEU1_ARCFU
Sequence: MSAVMTTIRVFDTTLRDGEQMPGVSLPLEYKIRIAKQLDKLGVDVIEAGFPSATKGEFESVKEISSLSLNAEICGLARIVKEDIDAAINANVDMVHIFVPTSRIQIEHTVKMSKEEIIEKSVECVEYIKSHGVKCMFSAMDATRTEVEYLKQIFKAVENAKVDIVNVPDTVGVATPFKFYELIKQLREHLKVPIDVHCHNDFGLAVANTYAAVMAGANEVQVTVNGIGERAGNADLAQVVMILHAIEGIKTNIKTEHLFETSKLVERLTGVKMPPNHPIVGENAFSHESGIHAHGVLKEYSTFEPGVVTPEMVGHKRRIVIGKHAGRYQIKKILEEAGYHLDDEKLNQIFEKVKEMGDKGKRVTDLDLFAIAEVVIGELKREEKAILVDEVTVLTGNKITPTAVLNAEVFGHRKVTSAIGVGPVDASLKAVTSLVGESIRITEFRMDAITGGSDALAEVYVTVEDDEGHSFTSRGAAQDIVMASIDAVINAVNYLLRMKRRKS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
Probable 2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.