PharMolix/UniProtQA huggingface dataset:
Protein: PHYB_NOSS1
Sequence: MNINDITIPFQVDLSNCSKEPIHIPGLIQPHGVLLVLQEVDLTILQVSNNTFNILGRHPEQLLNQHLSCLLEAEQLSLLKDCLAQEDLQIINPLEFIIKSHNESISFDVIAHRSNNLLILELEANLSDKTHSFFRFYHLVKLAMLKLQGTATTTEISQILAQEVRKITGFDRVMVYRFDEQWNGKVIAEVKPEYLTSYLGLNYPASDIPQQARKLYSQNWLRLIPDAKYQPVPIVPINNPLNDQPLDLSRSVLRSVSPLHIEYMQNMGVTASMSISIMKNQKLWGLIACHHQSPKYIPYEIRSACEFLGQMTSVEMSAKEDSEDTEDKIQVKSVHSKLVQYMSAENDFINALIDHQPNILDLVKAQGAAVCFNGNSCTVGQVPPMPDIQVLVEWMSQNIHEEIFATDSLATVYPDAEKLRDVASGLIALSISRSQKNYILWFRPEVVRTVDWGGNPHKPVEVIANGEIRLSPRKSFDLWKETVLLKSQPWKSHEVNAALELRSAIIGIVLQKADELAQLNIELERSNQELDAFAYIASHDLKEPLRGIHNYSNFLMEDYGEIIDAPGKEKLLTLIRLTQRMEDLIDSLLHFSRLGRVDLSMQDTDLNEIVHRILDMLSGRIEETGVEIRILQLLPVVYCDRIQIGEVFSNLIANSIKYNDKANKWIEIGYIDNPPLPPTFYVRDNGIGIREKHFETIFRIFKRLHSPSKYGGGTGAGLTIAKKIVERHGGKIWVESTYGEGSTFYFTLQDV
What is the function of this protein?
Photoreceptor which exists in two forms that are reversibly interconvertible by light: the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region.
What are the official names of this protein?
Cyanobacterial phytochrome B.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the phytochrome family.
Protein: RECX_LEGPC
Sequence: MTKAFDSALRLLTRREYSAMELCDKLKQKGFSTNDVQNALYECQRLGYQSDVRFVENYIRVRIHQGYGPLKIRQELKNKGIDPDLIQSVLHQEKDNWVNYALRAWEKKFKRQDDFSYSEIQKQQRFLLYRGFDRDVISKVFKEVKSSYLI
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_PSECP
Sequence: MATPTKVSAVAEITNDFKESNAAVLTEYRGLTVAQLKQLRVSLGQDTKFAVVKNTLTAIAAKEAGVEAFDGQLAGPTAIAFIKGDAVAAAKSLTDFAKANKQLVIKTGYFEGKALDASEVAALAALESRELQLAKVAGVLKAPAAAAARIIDALRLKLEEENGAPAAAEAPAAEESADSAAEAAAEAPAEAPAAEEN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: TFA_LAMBD
Sequence: MAFRMSEQPRTIKIYNLLAGTNEFIGEGDAYIPPHTGLPANSTDIAPPDIPAGFVAVFNSDEASWHLVEDHRGKTVYDVASGDALFISELGPLPENFTWLSPGGEYQKWNGTAWVKDTEAEKLFRIREAEETKKSLMQVASEHIAPLQDAADLEIATKEETSLLEAWKKYRVLLNRVDTSTAPDIEWPAVPVME
What is the function of this protein?
Chaperone that acts in assembly of the long tail fibers.
What are the official names of this protein?
Tail fiber assembly protein.
What is the protein family that this protein belongs to?
Belongs to the tfa family.
Protein: IF2_AERHH
Sequence: MAEVSVKQLATDIDTPVDRLLQQFVDAGISKSKADDMVSESEKQTLLAHLKKQHGGDEVAAPARMTLQRKTKSTISVQGTGGKNKEVQVEVRKSRTYVRRSALEDEQRQAEAEETARLEAEEKARREAEEKARLDAEEKARREAEQARREAEEKARIEAQQKARQAQQPAKAAGSTAQQEAEKMAKREAEELKRQQEQAALTKAEELAAKKAEEARVMAEQNAARWAEEEAARAKESSDYHLTTNKHAQAAEDELDRKEETSRRTAAAAKGPKKAGRREDDRDARNPRARKGKRGKVATPNAMKHGFNKPAAAVNRDVVIGETITVAELANKMAVKGVEVIKVMMKMGAMATINQVIDQETAQLVAEEMGHKVVLRRENELEEAVLSDRDETSEAKPRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVETDSGMITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAAEVPLVVAVNKIDKPEADPDRVKTELARYNVMSEDWGGDCQFVHVSAKSGQGIDDLLEAILIQSEVLELKAVVDGMANGVVIESFLDKGRGPVATVLVQEGTLRQGDIVLCGLEYGRVRAMRDELGREIKEAGPSLPVEILGLSGVPSAGDEATVVRDEKKAREVALYRQGKFREVKLARQQKAKLENMFANMTEGEVSEVNVVIKADVQGSVEAICDALVKLSTDEVKVKIVGSGVGGITETDATLAAASSAILVGFNVRADASARKVIEAESLDLRYYSVIYDLIDEVKQAMSGMLAPEYRQEIIGLAEVRSVFKSPKFGAVAGCMVTEGVVKRSNRIRVLRDNVVIYEGELESLRRFKDDVNEVKNGYECGIAVKNYNDVREGDQIEVYETVEIQRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AREG_MOUSE
Sequence: MRTPLLPLARSVLLLLVLGSGHYAAALELNDPSSGKGESLSGDHSAGGLELSVGREVSTISEMPSGSELSTGDYDYSEEYDNEPQISGYIIDDSVRVEQVIKPKKNKTEGEKSTEKPKRKKKGGKNGKGRRNKKKKNPCTAKFQNFCIHGECRYIENLEVVTCNCHQDYFGERCGEKSMKTHSEDDKDLSKIAVVAVTIFVSAIILAAIGIGIVITVHLWKRYFREYEGETEERRRLRQENGTVHAIA
What is the function of this protein?
Ligand of the EGF receptor/EGFR.  Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
What are the official names of this protein?
Amphiregulin, AR, Schwannoma-derived growth factor, SDGF.
What is the protein family that this protein belongs to?
Belongs to the amphiregulin family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RS4_ACTSZ
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKIDTAPGQHGARKPRLSDYGSQLREKQKVRRIYGILERQFRNYYKEANRLKGNTGENLLVLLEGRLDNVVYRMGFAATRAEARQLVSHKAIVVNGRVVNIPSFQVSVDDVVAIREKSKKQARIKASLELAEQKEKPTWLEVDSAKMEGVFKRVPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: ENO_BUCAI
Sequence: MSKITKIIAREIIDSRGNPTVESEVHLEGGFVGLASSPSGASTGSLEALELRDENKDRFMGKGVEKAVSLINEKISIALKNKNARNQSDIDHIMIDLDGTINKSKLGANAILSVSLAVAKAAAASKRMPLYAHIAEINETPGVFSMPLPMINIINGGKHANNNIDIQEFMIQPISAKTVKESIRIGCEIFHALGELLKEKGMSTTVGDEGGYAPNLKSNEEALNIIQDAIQKTKYKLGQDIRLAIDCAASELYNKNEKKYNLKGENISFSSKEFTHYLEKLSQKYPIVSIEDGQDESDWEGFLYQTHVLGNKIQLVGDDLFVTNKNILKKGIKKGIANSILIKLNQIGTLTETLEAIKTAKQANYGVIISHRSGETEDASIADLSVGTSSGQIKTGSMSRSDRTSKYNQLIRIEENLGTKYAPFHGLREIKSAF
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRMB_XYLFM
Sequence: MMNLLSSDGVQVLPRPFTLNERRREVRSFVLRQGHFTPAQKRAFDHYWPRFGVDFIGQLRDLDVLFGRSAPKVLEVGFGNGAALRFAAQHEPRYDYIGIEVYAPGVGRLLNGLAEDGSRHVRLYHYDAVEVLNKEIADGALDEIRIYFPDPWHKKRHHKRRLIQPLFATLLVRKLRVGGCLHMATDWADYAEQMWDVLDATPGLVNRAGLRGQVPCPDWRVQTRFERRGQNLGHRVWNLLYDRV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: SOTB_SALSV
Sequence: MTINPVSRKVAWLRVVTLAIAAFIFNTTEFVPVGLLSDIAESFHMQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKLLICLFVLFIASHVLSFLAWNFTVLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGLPIGRVVGQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSLYVLTVVVVTAHYTAYSYIEPFVQNVAGLSANFATVLLLILGGAGIIGSLVFGKLGNRHASSLVSIAIALLVICLLLLLPAANSEAHLAILSIFWGIAIMVIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSAIGYIGAIPACAALVWAVLIFRKWPVTLEEQPH
What is the function of this protein?
Involved in the efflux of sugars.  The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
What are the official names of this protein?
Probable sugar efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KCY_MESFL
Sequence: MKRKIVIAVDGTAGSGKTATFNTVAKKIGYEFIDTGLMYRAFTLLCIESEIDFNNKEEIIESLKKFDFSVKNNKPHLNGKEVEKRIQENDIVKFINYVTPIPEVRKFMVEAQRAMVKGGGYIEIGRDITTVVLPNADLKIFLDSSVEARAERRFKQNERLGIKNNNLNEIKNSIINRDEQDFKNGLRKAEDAWLIDNSNIPIQDVVNMVIDKIKELEGN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G9P_BPIF1
Sequence: MSALSYFFAAYCIGWVISHSILVFKKLSEVST
What is the function of this protein?
May initiate with G7P the virion concomitant assembly-budding process, by interacting with the packaging signal of the viral genome.  The assembly-budding takes place at the host inner membrane.  In turn, G7P and G9P are present at the end of the filamentous virion that emerges first from the bacterial host (By similarity).
What are the official names of this protein?
Tail virion protein G9P, Coat protein C, polypeptide II, G9P.
What is the protein family that this protein belongs to?
Belongs to the inovirus G9P protein family.
What are the subcellular locations of this protein?
Virion. Host membrane; Single-pass membrane protein. Note=Prior to assembly, is found associated with the bacterial host inner membrane. There are about five copies of this protein per mature phage that are located on the tail side of the filamentous virion with G7P (By similarity).
Protein: Y017_METJA
Sequence: MRLTIEVIKEKIVERKLFKRNRKSIEVKILAGLLYYLGLSLRKVSLFLSQFEDISHESVRIYYHKIKEVLNEPERKERNLIAIDEIKLKVGDKYIYAWSAIDVETKECLGVYISKTRNYLDTILFVKSILKFCSNKPKILVDGGKWYPWALRKLGLEFEKVKFGLRNCVESFFSVLKRRTKAFFNRFPNNSKFDTVISWIKSFMMFYNWVKSLT
What are the official names of this protein?
Uncharacterized protein MJ0017.
Protein: CAIT_ECOLI
Sequence: MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD
What is the function of this protein?
Catalyzes the exchange of L-carnitine for gamma-butyrobetaine (PubMed:12163501, PubMed:20829798, PubMed:30846799).  Can also transport D-carnitine and, with lower efficiency, acetyl-L-carnitine and glycine betaine (PubMed:12163501).
What are the official names of this protein?
L-carnitine/gamma-butyrobetaine antiporter.
What is the protein family that this protein belongs to?
Belongs to the BCCT transporter (TC 2.A.15) family. CaiT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS8_METS4
Sequence: MSAALRPVPRPGVLAIEAYVPGKSAAPAGVKLHKLSSNETPLGPSPAAVAAMRETASHLELYPDGSAAALRRAIAGKYGLDPARIVCGAGSDELLSLLTYAFMGPGDEGIYSEYGFLVYRIAILAAGGTPVVAPERDHTADVDAILAAVTPRTRIVYLANPNNPTGTYLPFDEVRRLHAGLPGDVLLVLDAAYAEYVRRNDYAAGLELVAESENVVMTRTFSKAYGLAALRIGWMVAPPAVADAVNRIRGPFNLGSPAIAAGAAAVADDAHIAAAVAHNEEWLPKVTRALTEIGLSVTPSVGNFVLIHFPDAPGRGAAEADAFLTARGLILRRVAAYGLPHALRMTIGSAEANEAVIAALRAFVKDHPDA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: GUNA_CALSA
Sequence: MVVTFLFILGVVYGVKPWQEARAGSFNYGEALQKAIMFYEFQMSGKLPNWVRNNWRGDSALKDGQDNGLDLTGGWFDAGDHVKFNLPMSYTGTMLSWAAYEYKDAFVKSGQLEHILNQIEWVNDYFVKCHPSKYVYYYQVGDGGKDHAWWGPAEVMQMERPSFKVTQSSPGSAVVAETAASLAAASIVLKDRNPTKAATYLQHAKDLYEFAEVTKSDSGYTAANGYYNSWSGFYDELSWAAVWLYLATNDSTYLTKAESYVQNWPKISGSNIIDYKWAHCWDDVHNGAALLLAKITDKDTYKQIIESHLDYWTTGYNGERIKYTPKGLAWLDQWGSLRYATTTAFLAFVYSDWSGCPTGKKETYRKFGESQIDYALGSTGRSFVVGFGTNPPKRPHHRTAHSSWADSQSIPSYHRHTLYGALVGGPGSDDSYTDDISNYVNNEVACDYNAGFVGALAKMYLLYGGNPIPDFKAIETPTNDEFFVEAGINASGTNFIEIKAIVNNQSGWPARATNKLKFRYFVDLSELIKAGYSPNQLTLSTNYNQGAKVSGPYVWDSSRNIYYILVDFTGTLIYPGGQDKYKKEVQFRIAAPQNVQWDNSNDYSFQDIKGVSSGSVVKTKYIPLYDEDIKVWGEEPGTSGVSPTPTASVTPTPTPTPTATPTPTPTPTVTPTPTVTATPTPTPTPTSTPTVTPTPTPVSTPATSGQIKVLYANKETNSTTNTIRPWLKVVNSGSSSIDLSRVTIRYWYTVDGERAQSAISDWAQIGASNVTFKFVKLSSSVSGADYYLEIGFKSGAGQLQPGKDTGEIQIRFNKDDWSNYNQGNDWSWIQSMTSYGENEKVTAYIDGVLVWGQEPSGTTPAPTSTPTVTVTPTPTPTPTVTPTPTVTATPTPTPTPTSTPVSTPATGGQIKVLYANKETNSTTNTIRPWLKVVNSGSSSIDLSRVTIRYWYTVDGERAQSAISDWAQIGASNVTFKFVKLSSSVSGADYYLEIGFKSGAGQLQPGKDTGEIQIRFNKDDWSNYNQGNDWSWIQSMTSYGENEKVTAYIDGVLVWGQEPSGATPAPTVTPTPTVTPTPTPAPTPTATPTPTPTPTVTPTPTVAPTPTPSSTPSGLGKYGQRFMWLWNKIHDPASGYFNQDGIPYHSVETLICEAPDYGHLTTSEAFSYYVWLEAVYGKLTGDWSKFKTAWDTLEKYMIPSAEDQPMRSYDPNKPATYAGEWETPDKYPSPLEFNVPVGKDPLHNELVSTYGSTLMYGMHWLMDVDNWYGYGKRGDGVSRASFINTFQRGPEESVWETVPHPSWEEFKWGGPNGFLDLFIKDQNYSKQWRYTNAPDADARAIQATYWAKVWAKEQGKFNEISSYVGKAAKMGDYLRYAMFDKYFKPLGCQDKNAAGGTGYDSAHYLLSWYYAWGGALDGAWSWKIGCSHAHFGYQNPMAAWALANDSDMKPKSPNGASDWAKSLKRQIEFYRWLQSAEGAIAGGATNSWNGRYEKYPAGTATFYGMAYEPNPVYRDPGSNTWFGFQAWSMQRVAEYYYVTGDKDAGTLLEKWVSWIKSVVKLNSDGTFAIPSTLDWSGQPDTWNGTYTGNPNLHVKVVDYGTDLGITASLANALLYYSAGTKKYGVFDEEAKNLAKELLDRMWKLYRDEKGLSAPEKRADYKRFFEQEVYIPAGWTGKMPNGDVIKSGVKFIDIRSKYKQDPDWPKLEAAYKSGQVPEFRYHRFWAQCDIAIVNATYEILFGNQ
What is the function of this protein?
The N-terminal domain of CelA codes for an endoglucanase activity on carboxymethylcellulose.  The C-terminal domain probably acts synergistically to hydrolyze crystalline cellulose.
What are the official names of this protein?
Endoglucanase A, Cellulase A, Endo-1,4-beta-glucanase A.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the glycosyl hydrolase 9 (cellulase E) family.
Protein: CSPL9_ORYSI
Sequence: MRSGEGSTAAAAAAEEEKVKVAAPFRLAELGLRVCAVPLAVASVWEMATNKQVDETYGEVRFSDLSGFRYLVWINAITAAYSVASILLSSCRFITRFDWLIFILDQASAYLLLTSASAAAEVVYLAREGDREVSWGEVCSYFGRFCGAATVSVALNAAALLCFMALSLISAFRVFTKFNPPSQSNSKQQLSQEQGKPVVSG
What are the official names of this protein?
CASP-like protein 2D1, OsCASPL2D1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL33_STASA
Sequence: MKKVPLNCEVCGNRNYNVPKQSNLASRLELKKYCPRCNAHTLHKESK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RS21_HAES1
Sequence: MPVIKVRENESFDVALRRFKRSCEKAGILAEVRSREFYEKPTTIRKRENATRAKRHAKRVARENARNTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: QUEC_XANCB
Sequence: MKKAVVLLSGGMDSAAVIALAQEQGFAVHALSVRYGQRHTSELDAAARVAAAQGVVAHKVVDVDLRSIGGSALTADIDVPEAGGAGIPVTYVPARNTIMLSLALGWAEVVGANDLFCGVNAVDYSGYPDCRPEFVRAFEVLANLATKAGVEGAGLRVHAPLQFLSKADIVRAGVRLGVDFGLTVSCYNADADGRACGHCDACRLRAAGFADAGVPDPTHYAISS
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ATG4_MEDTR
Sequence: MVLKDLCDRIVAAKCSSKSSTEIVDNTQVPASSKAGSSDSKFPKASLWSTFFTSGFSVDETYSESSSSEKKTVHSRNSGWAAAVRKVVSGGSMRRFQERVLGSCRTDVSSSDGDIWLLGVCHKISQHESTGDVDIRNVFAAFEQDFFSRILITYRKGFDAIEDSKYTSDVNWGCMLRSSQMLVAQALLFHKLGRSWRKTVDKPVDKEYIDILQLFGDSEAAAFSIHNLLQAGKGYGLAVGSWVGPYAMCRTWEVLARNQREKNEQGEQLLPMAIYVVSGDEDGERGGAPVVCIEDACKRCLEFSRGLVPWTPLLLLVPLVLGLDKVNLRYIPLLQSTFKFPQSLGILGGKPGASTYIIGVQNDKAFYLDPHEVKPVVNITGDTQEPNTSSYHCNISRHMPLDSIDPSLAIGFYCRDKDDFDDFCSRATKLAEESNGAPLFTVAQSRSLPMQVTSNSVSGDDTRFEEDDSLSMNLVNDAGNEDDWQFL
What is the function of this protein?
Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.  The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine (By similarity).  Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy.  In addition to the protease activity, also mediates delipidation of PE-conjugated ATG8 proteins (By similarity).
What are the official names of this protein?
Cysteine protease ATG4, Autophagy-related protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C54 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3SAFA_NAJAT
Sequence: LKCKKLVPLFSKTCPPGKNLCYKMFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin SP15a.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: RL21_ACIC5
Sequence: MYAVIRTGGKQYRVAPGDVLKIETAAANQDGQIEFSEVLAFSGETGSVVKPGAAKVLASVEGEGRGDKILVFHYKRKKQYKKLQGHRQNFTQIRIQEIQIDGNSYRAQ
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GREA_CLOB6
Sequence: MSEAKKYVMTYEGVKKLEEELEYLKTVKRKEITEKIKVALSFGDLSENSEYDEAKNEQAFVEGRIIQLENMLKNASIVDENEVPKDIVSVGSIVKVKDYEFDEEVEYIIVGSAEADPMNNKISNESPVGHGLIGKKVGDIIEVTVPDGVSKYEILEVNRA
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ALLS_ECOL5
Sequence: MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTAAGEHLLCQARDWLSWLESMPSELQQVNDGVERQVNIVINNLLYNPQAVARLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFSLDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGFLPKSLCQSMLDNQQLVSRVIPTMRPPSPLSLAWRKFGSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS
What is the function of this protein?
Positive regulator essential for the expression of allD operon.  Binds to the allD promoter (By similarity).
What are the official names of this protein?
HTH-type transcriptional activator AllS.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: ACLA1_ARATH
Sequence: MARKKIREYDSKRLVKEHFKRLSGKELPIRSVQINETTDLNELVEKEPWLSSEKLVVKPDMLFGKRGKSGLVALKLDFADVATFVKERLGKEVEMSGCKGPITTFIVEPFVPHNEEYYLNVVSDRLGCSISFSECGGIEIEENWDKVKTIFLPTGASLTPEICAPLVATLPLEIKAEIEEFIKVIFTLFQDLDFTFLEMNPFTLVDGSPYPLDMRGELDDTAAFKNFKKWGDIEFPLPFGRVMSPTESFIHGLDEKTSASLKFTVLNPKGRIWTMVAGGGASVIYADTVGDLGYASELGNYAEYSGAPKEDEVLQYARVVIDCATANPDGKSRALVIGGGIANFTDVAATFNGIIRALKEKEAKLKAARMHIFVRRGGPNYQKGLAKMRALGDDIGVPIEVYGPEATMTGICKEAIQYITAAA
What is the function of this protein?
ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA, used for the elongation of fatty acids and biosynthesis of isoprenoids, flavonoids and malonated derivatives.  May supply substrate to the cytosolic acetyl-CoA carboxylase, which generates the malonyl-CoA used for the synthesis of a multitude of compounds, including very long chain fatty acids and flavonoids.  Required for normal growth and development and elongation of C18 fatty acids to C20 to C24 fatty acids in seeds.  In contrast to all known animal ACL enzymes having a homomeric structure, plant ACLs are composed of alpha and beta chains.
What are the official names of this protein?
ATP-citrate synthase alpha chain protein 1, ATP-citrate synthase A-1, ATP-citrate lyase A-1, Citrate cleavage enzyme A-1.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL11_NITWN
Sequence: MAKKVTGYLKLQVPAGAANPSPPIGPALGQRGLNIMEFCKAFNAQTQKEEKNTPIPVVITIYADRSFTFEMKTPPMAYFLKQAAKIQSGSKTPGRDAAGTLTRAQVREIAEKKMKDLNCDTVEAAMSMVEGSARSMGLQVAE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: MFD_STAS1
Sequence: MKSIITEYINEDKRYQELNEVFGKENVLVTGLSGAAKATIIAEKYLNSEQQLLVVTNNLYQADKLESDLLQFVEDSEIYKYPMQDIMTEEFSTQSPQFMSERVRTLTALAQEERGLFIVPLNGLKKWLTPVDMWKSHQLTLNVGDDIDIDEFLNKLVNMGYRRESVVSHIGEFSLRGGIVDIYPLIGKPVRIEFFDTEVDSIRDFDVESQRSEGNIEHVDITTASDYIITEDVLKHTKHKLKQAYEDTRPKIEKSVRNELKETYESFQLFEAEMFDHQVLRRLVAFMYEQPATIMDYFKEDAIIAVDEYNRIKETETTLVTEIDEFMQNLIESGKGFIDQSFLQYEGFENLLKPFAVTYFTLFTATMPVQLNEIIKFSCKPVQQFYGQYDIMRSEFQRFIQNDYTIVVLAETETKKERIQSMLNEMHIPTFIDTPSRRNEGGSAIITEGSLSEGFELPYMQLVVVTERELFKSKQKKKPKQHKTLTNAEKIKSYQDLKVGDYVVHVHHGVGRYLGVETLEVGGVHKDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKSPKLNKLGGTEWKKTKAKVQQSVEDMADELIELYKAREMSVGYKFGPDTAEQNDFEIDFPYELTPDQSKSIEEIKQDMEIERPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQHYETLIERMQDFPIEVQLISRFRTTKEVKETKEGLKSGFVDIVVGTHKLLGKDIQYKDLGLLIVDEEQRFGVRHKERIKSLKNNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPPENRFPVQTYVLEQNTNFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANIGVAHGQMNERDLEETMLSFINHEYDIIVTTTIIETGVDVPNANTLIIEDADRFGLSQLYQLRGRVGRSSRIGYAYFLHPTNKVLSETAEDRLQAIKEFTELGSGFKIAMRDLNIRGAGNLLGKQQHGFIDSVGFDLYSQMLEEAVNEKRGIKAEKQDAPEIEIELNIDAYLPAEYIPNEQSKIEIYKKLRKIESETQLMDVKDELIDRFNDYPIEVERLLEMMEIKVHALHAGVTLIKDVGKQVEVYLSEKGTTDINGETLFKQTQPLGRTMKVGVQEGKMKVTLNKTGNWLDSLKFLTKSLEESMVITDEI
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.