PharMolix/UniProtQA huggingface dataset:
Protein: SECA_SULDN
Sequence: MLQALMGKIFGTTNDRELKRYRQIVNKINNLESKYKALSDEALKSAFNEIKESVLSGGKSLDSVLVDSFAITREASTRVLNMRHFDVQLIGGIVLHEGKIAEMKTGEGKTLVATLPIVLNAISGKGVHLVTVNDYLASRDGNEMRPLYEFLGFSVGVILENMHDPVVKREVYNADITYGTNNEFGFDYLRDNMSYSRENMVQRGHNFVIVDEVDSILIDEARTPLIISGPTNRTLRDFKDANDIALKLLKDEHFSVDEKDKTVLLTEEGITRAEELFKVENLYSPENASLSHILDQALKANYLFEKDVDYVVNNGEVVIVDEFTGRLSEGRRFSEGLHQALEAKESVEIKEETQTLADITFQNYFRMYNKLAGMTGTAQTEASEFAQIYSLDVISIPTNIPILRKDLNDLIYKTEKEKFEAVIATIKKLSATGQPVLIGTASIEKSEILHEVLKKEKIAHTVLNAKNHAQEGEIIKNAGAKGAVTIATNMAGRGVDIKVNDEVKALGGLYIVGTERHENRRIDNQLRGRSGRQGDNGTTQFYLSLEDSLLRIFGSDKIKSIMERLGVEDGEYIESKMVTRAVEKAQKKVENMHYEGRKHIVEYDDVANEQRKIVYKFRNQLLDPEFNISMKINEIRAEYVAHLFANVSIFNGGVKEDFNLEKLFKLIHEEINLELNPADFASYEYEELLEVLTQKIKSSYDEKMSVLNDSICSEIERELYLKELDSAWREHLYAMDNMKTGIRLRAYNQKDPLVEYKKESFNLFTELVEDIKFNTIKTLQIIQFRVEDPEEEARRVAEKLDIQRKMNEASIQFNHYQSEMENESKKISRNDLCPCGSGKKYKLCCGKSGPKKGVFAS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS3_CHLAB
Sequence: MGQKGCPIGFRTGVTKKWRSLWYGNKQEFGKFLIEDVKIREFLRKKPSCQGAAGFVVRRMSGKIEVTIQTARPGLVIGKKGAEVDLLKEELRKLTGKEVWVEIAEIKRPELNAKLVADNIARQIERRVSFRRAMKKAMQSVMDAGAVGVKIQVSGRLAGAEIARSEWYKNGRVPLHTLRADIDYAAASAATTYGIIGVKVWINLGEKASTASSNVGTAAPVVQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL5_ACIC1
Sequence: MTTTHPALTAGRPAGYVPRLKQYYREHVVPALREQFGYRNVMQVPTLVKVVVNMGVGEAARDAKLIEGAVRDIAAITGQRPAIARARKSIAQFKLRAGMAIGAYATVRGDRMWEFLDRMLTLALPRIRDFRGLSPKQFDGHGNYTFGLTEQVMFHEVDQDKLDRFRGMDITVVTTARTDDEGRALLRHLGFPFREN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DBP5_USTMA
Sequence: MSESKDKTTAPAADSNVNEIASGISGLLSSKDVAESNLRESSHEVQVTLADQQADPNSPLYSAKSFEALGLHENLLKGIYAMKYQKPSKIQEKALPLLLQNPPKNMIGQSQSGTGKTAAFILTMLSRIDYDLQKPQAIALAPSRELARQIMDVARTMSKFTNVTTCLCLPDEVKRGEKITAQLIIGTPGKTFDMIKSKGIDTAAIKVFVLDEADNMLDQQSLGEQSIRVKNTMPKSCQLVLFSATFPTNVYDFAVRIAPGANEIRLKQEELSVEGIKQFYMDCKDEDHKYEVLVELYNLLTIGQSIIFCAKRETADRIAQKMTQEGHKVDSLHGRLETADRDRTIDAFRDGKSKVLISTNVIARGIDIQQVTLVINYDMPLTQTGEADAETYLHRIGRTGRFGRKGVSINFVHDQQSWSYMDQIEKALKCQITRVATNDLEEMEYTIKEALKQIGK
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: UROK_CHICK
Sequence: MKLIIFLTVTLCTLVTGLDSVYIRQYYKLSHKHRPQHRECQCLNGGTCITYRFFSQIKRCLCPEGYGGLHCEIDTNSICYSGNGEDYRGMAEDPGCLYWDHPSVIRWGDYHADLKNALQLGLGKHNYCRNPNGRSRPWCYTKRRYSIQETPCSTIEKCERTCGQRSFSKYFKIVGGSQAEVETQPWIAGIFQNIMGTDQFLCGGSLIDPCWVLTAAHCFYNPTKKQPNKSVYKVFLGKSILNTNDEHEQVFMVDEIISHPDFTDHTGGNDNDIALIRIRTASGQCAVESNYVRTVCLPEKNLNLYDNTWCEIAGYGKQNSYDIYYAQRLMSATVNLISQDDCKNKYYDSTRVTDNMVCAGDPLWETDACKGDSGGPMVCEHNGRMTLYGIVSWGDGCAKKNKPGVYTRVTRYLNWIDSNMNAVFTKSRSFREPK
What is the function of this protein?
Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
What are the official names of this protein?
Urokinase-type plasminogen activator, U-plasminogen activator, uPA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VF391_IIV3
Sequence: MLQNVIKELYDKGVLIFLDPNNYVTNNVAENPEIFANRDKFLEMYQDPIKIGWIFCYTPSLEEVLSTIKEDTCCLIEFGFNSDTEKKACETGRLLINHLVRHKFMAHWDENAIKNHKISTVITAKDLPESIQDLIVDYAPTTSTNPEQRE
What are the official names of this protein?
Uncharacterized protein 058R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 391R family.
Protein: LORF1_MOUSE
Sequence: MAKGKRKNPTNRNQDHSPSSERSTPTPPSPGHPNTTENLDPDLKTFLMMMIEDIKKDFHKSLKDLQESTAKELQALKEKQENTAKQVMEMNKTILELKGEVDTIKKTQSEATLEIETLGKRSGTIDASISNRIQEMEERISGAEDSIENIDTTVKENTKCKRILTQNIQVIQDTMRRPNLRIIGIDENEDFQLKGPANIFNKIIEENFPNIKKEMPMIIQEAYRTPNRLDQKRNSSRHIIIRTTNALNKDRILKAVREKGQVTYKGRPIRITPDFSPETMKARRAWTDVIQTLREHKCQPRLLYPAKLSITIDGETKVFHDKTKFTQYLSTNPALQRIITEKKQYKDGNHALEQPRK
What is the function of this protein?
Nucleic acid-binding protein which is essential for retrotransposition of LINE-1 elements in the genome.  Functions as a nucleic acid chaperone binding its own transcript and therefore preferentially mobilizing the transcript from which they are encoded.
What are the official names of this protein?
LINE-1 retrotransposable element ORF1 protein, L1-ORF1p, LINE retrotransposable element 1, LINE1 retrotransposable element 1, Transposase element L1Md-A101/L1Md-A102/L1Md-A2.
What is the protein family that this protein belongs to?
Belongs to the transposase 22 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm, Stress granule. Note=Colocalizes with its encoding RNA in cytoplasmic ribonucleoprotein particle. Mainly cytoplasmic, rarely detected in the nucleus, possibly within the nucleolus.
Protein: TNR18_HUMAN
Sequence: MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
What is the function of this protein?
Receptor for TNFSF18.  Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.  Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein.
What are the subcellular locations of this protein?
[Isoform 1]: Cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: IF1_SALRD
Sequence: MAKEEAIEKDGEVIEALPNAQFRVRLENGHEILGLLSGKMRMNYIKILPGDRVKVEMSPYDLSKGRIVYRYKN
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCC29_ARATH
Sequence: MTKQVGKKFAWVIKNFSSLQCKKFYSVPFQIGDCKWRLSIYPKGNNCDYLSLFLEVADFKSLPSGWRRYVKLRLYIVKQLSTLIRKTHRWFDQEMWGWGFLYMLPLTKLHDEKEGFLVNGELMIVAEVDALGFIDPLNESEESEDPTQPLKKIKLNDDGAVSSDLLEEASPRKESMEVNGFQVLPSQVESVRLIFERHPDIASEFRAKNQYLRKACMDFLLSLVETLCQSLQEFSNEDLVEADIALTYLKDAGFKVDWLEKKLDQVRDKKEKERSCLAKLQETEETLLKLKQKCTELDALMDTEKAELSAIRTPLSFEDVV
What are the official names of this protein?
MATH domain and coiled-coil domain-containing protein At3g58410, RTM3-like protein At3g58410.
Protein: HSLO_RUMCH
Sequence: MGDYIVRMTAAQGTVRAFGAMTTEMVGQAAEIHGLSPIATAALGRTMTAAGMMSKMLKGENDKLTIQLKGDGPLGGIVVVSDSKANVRGYVHNPNVYLPLNERGKLDIRTAMGYGYINVIRDMGLKEPYIGLSQLVSGEIADDLTYYFATSEQVPSTVALGVLIDATGVIGAGGFIVQMMPGAEEETVATLEKRLIGFPSVSKLISEGTTPEQILNMLLEGMEPKIVETVPCSFKCNCTRERMERNLISIGKKDLLEIFEDGKGAELQCHFCNTKYNFSHQDIENIVKENVK
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA6A_ARATH
Sequence: MSRGSGAGYDRHITIFSPEGRLFQVEYAFKAVKTAGITSIGVRGKDSVCVVTQKKVPDKLLDQSSVTHLFPITKYIGLVATGITADARSLVQQARNQAAEFRFTYGYEMPVDILAKWIADKSQVYTQHAYMRPLGVVAMVMGVDEENGPLLYKCDPAGHFYGHKATSAGMKEQEAVNFLEKKMKENPSFTFDETVQTAISALQSVLQEDFKATEIEVGVVRAENPEFRALTTEEIEEHLTAISERD
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit alpha type-6-A, 20S proteasome subunit alpha A-1, Proteasome component 1, Proteasome subunit alpha type-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ACES_MOUSE
Sequence: MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPVSAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTELIACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVGVVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPEDPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGYEIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQYVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKNQFDHYSKQERCSDL
What is the function of this protein?
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
What are the official names of this protein?
Acetylcholinesterase, AChE.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Synapse. Secreted. Cell membrane; Peripheral membrane protein. SUBCELLULAR LOCATION: [Isoform H]: Cell membrane; Lipid-anchor, GPI- anchor; Extracellular side.
Protein: KIBRA_DROSE
Sequence: MPNLQQTASQSQHHLHPHHLRPQQQQQQQQHHHQQQRQQQQHTHHQQQHHSDFPLPDGWDIAKDFDGKTYYIDHINKKTTWLDPRDCYTKPQTFEDCVGDELPMGWEESYDPNIGPYYINHLAQSTQLEDPRQEWKSVQEQMLSDYLSAAQDQLENKREMFDVKQQRLLWAQEEYNHLKLAASRSSLCSSSSSMSRHDPELLRADLMLARERVHQLKQELTHITNDISYTERGMNTLYSVGEKINARENGCYDIAEVQAIHEEMLKVHKSLVSGEKVREELMRSLVQIKNELGRQQISEENSDLASPFDRVCVASQTDLCGSSGDNLNEGARFAEMAKTTLQYAEWRKHIKKLQQQLADHVERIEPGQLESDKDRILLIQEKEKLLNDLNSISLKSRSEEEKRVIHQTRHKLEEDLKEAYEANNTCVANRLRFHEEKQLLLDKLQEALKSTKLLEERLKTFSSESTFSISSGSSLGSLVHGQHKSALSFTDIYIDPFAVDSPIDVVDLRRRSQRLFQQHQQQRLHPVHPVLQQQQSAEVTLSPRSSLSMETPPASPMKYNAGADQTPQALKEEPTYANALHAPPAYTAPPPVPISGVRARPYDLDSTVLDCMMLEAKLQKLNMGTPLNLAVAPLSPISEKPSLLDLPQEMLSRSSSTSNTRSVSAAVSNESVAGDSGVFEASRAHLPRKELAQVQIGLKYLKQEGVLVVSLERANNLLALWTASADNSQVYLRAALLPNSLTSIRTKALGDFQKPVFNDTFAVPITLDKLLTKSLQVTVVTMTGQKEEIIGTVQISMAEFNPEDSTLKWYNVLSSKFIPSFESLDIPSTSAAAAAAAVAASNAPNPGNNREESSDESTITSSQTSTLTRNQAPCMELQEQIAAELMGLGPLNEPECSDDDDDDEEEELEDKQLVSDVGLMNSSSMLHAYLQNMKQEFADKETNTDRAYLPEKSRGQSQLMDDRPVKRSQTFTPSAAVSKNRYNCRLNRSDSDSAMHCGVAPHTFQRGAAERRSLRYLSKAPKSVTKLHHTHIPRTSLDLELDLQAQHSKLYFLNDQIAKLQNLKEVLQKACDNKDPLVAAWAIENEEFQRLVARADPAKCPEERQLQKLLMKTAKEIHKLRKTKVPKGCPDLVSFKEKITFFTRKGLSVPELPSEFTLPEANPIEEEEEEEDEDEFYNSPETAIAINTALVASSNRNKNLSEHLHRATSGAVPKIPAPVVTPAVTPAAAPAATPAATPAATPAATSAATPAATPVVSPAAQPDAKAADAPIPVASNDAEQQRFDYVVDRNYGVEV
What is the function of this protein?
Regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.  The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein.  Kibra acts synergistically along with Ex and Mer to regulate the Hippo signaling pathway (By similarity).
What are the official names of this protein?
Protein kibra.
What is the protein family that this protein belongs to?
Belongs to the WWC family. KIBRA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Apical cell membrane. Note=Localizes at the apical cortex of epithelial cells and cytoplasmic, punctate.
Protein: SAC7_YEAST
Sequence: MPNNTLKQGSKIENVSPSKGHVPSFWKQFINNPKSMSSENITVPRSPTSLSRNAQPTTLKRPPLSSRPYSYNTPTKDRKSFSKSAKQNNNNNNANSGTSPHAEFKNYRDMFLSNRNGFTGRVFGVTLAESLSVASAEVIVQSELVSFGRIPIVVAKCGAYLKANGLETSGIFRIAGNGKRVKALQYIFSSPPDYGTKFNDWETYTVHDVASLLRRYLNNLAEPLIPLSLYEQFRNPLRSRPRILRHMLTHEVSHPNANKTNNVTVKSSRQNYNDDGANDGDIEKEDAKDDEEKRRRKIRHKRRLTRDIRAAIKEYEELFVTLSNDTKQLTIYLLDLLSLFARQSQFNLMSGRNLAAIFQPSILSHPQHDMDPKEYELSRLVVEFLIEYSYKLLPHLLKLAKREQQERLSTENKKNNGDKQKTDPIEIPKITSSDSPPIVSSNKNPPAIDNNNKLDHTTLSPISTSIPENSSDLQTSKMLKPPKQRRPHSKSFGSTPVPPDVIASNKRRTSLFPWLHKPGILSDTGDNGDLTATEAEGDDYEEENVDPYGQSPSSVHSGSLPKQHYLPIPRMNRSLSGNSTNSSFNTRPISMILTSGNDNSADQLELLSNTHSNNERSNALPLTEDDGDERNSRSRKRESWFQRLTSRSGSANRA
What is the function of this protein?
GTPase-activating protein for RHO1.  Must be involved in the normal assembly or function or both of actin.  Plays an essential role only at low temperatures.
What are the official names of this protein?
GTPase-activating protein SAC7.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL24_BLOFL
Sequence: MSANKIRCHDEVVVLTGKDKGKIGRVKFLCLSKKTVIVSGINVVKKHQKPVPNKNQPGGIIEKEAFIHLSNVAIFNAALNKADRVGFKIKNGKKIRIFKSNGNLIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: QUEF_PSEAE
Sequence: MQHPAEHSPLGKTSEYVSSYTPSLLFPISRTAKWAELGLSAETLPYRGVDIWNCYELSWLTPAGKPVVAIGEFSIPADSPNIIESKSFKLYLNSLNQSAFDSREALRAVLQKDLSAAVGAPVGVRLRSLDEVAEEGIGRLPGRCIDELDIAVDGYEQPRPELLRCDAGRIVEEQLYSHLLKSNCPVTGQPDWGTLVVDYRGPALDPASLLAYLVSFRQHQDFHEQCVERIFLDLQRLLQPQALSVYARYVRRGGLDINPYRSLAEVAPDNRRLVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CO005_HUMAN
Sequence: MLKNRELLKIFEQASHMMKLIEEHCICDCIWMEWEDLEAKTLDRRPPEQTRRERCSCGNGKRWAKPKITTEKKNHPDFMIDWMYFETPLSIQMK
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00597.
Protein: KIF22_DANRE
Sequence: MAQRVAVNDGAAGSKRTSRVRVAVRLRPYMDKQDEKSEGSCVRGLGPQKLEIINWRNATETLQYQFDVFHGEETTQQEVFLTSVKPILPHILNGQNASVFAYGPTGAGKTHTMLGSQEQPGVIPRAVKEVFNLVGAQKKEQDGWEYSIGMSYLEIYNEKVLDLLSPGSQDLPIREDKDRNILIPGLTHTPLSSFADFDTHFIPASLNRTTASTKLNQRSSRSHAILLIKVVKSQRGPPHRQQTGKLYLVDLAGSEDNRRTGNQGIRLKESGAINLSLFTLSKVVDALNTGAGGRVPYRDSKLTRLLQDSLGGSAHSVMITNIAPEYKYYFDTFSALNFAAKSKQIVNRPFVRETVLAPTIAPGKRTREEQEAGGSGEPQNKRSKEGKKAEHSPSPPLHPQSSPDSSVLDRLLALEKMMMGSAERERLNLLKTVAQSRKEIQMLKEKQKELEDKANMFNKQKETTEKESKDALLFKTDLPPLHRKQSTAAKPRKQQAVVTPLQVSQVQPLQQCAVVCKPSQTLVKKKRVQTEVCDGKENIGVDLPPVEDVNWESRLDPALLEQSRKKILQTLNSGSLKELKSLQQIGDKKAKLIMGWREINGDFTQVEDLKKIEGVTVKRFSSFIKANILSSMGK
What is the function of this protein?
Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis.  Binds to microtubules and to DNA.
What are the official names of this protein?
Kinesin-like protein KIF22.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton.
Protein: RS11_METAC
Sequence: MADMKWAVAHIKSSFNNTIITVTDITGAETIAKSSGGMVVKAARDESSPYTAMQMAGQLADQLKDKGINGIHIRVRAPGGNKQRSPGPGAQAAIRAFARAGIRIGRIEDVTPVPHDGTRPKGGRRV
What is the function of this protein?
Located on the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: IXTPA_LEPIN
Sequence: MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKENALIKAKELFYLTKIPSIADDSGICVSALKDEPGVYSARFGGPELNDEGRALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGIYGFGYDPIFIFPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SPC97_YEAST
Sequence: MEIKEVDDRAELLRYTNNIPLLGKLVNHQPLWSTNPKLKSFSLEKISAPDQRRVQEALVVKDLLNVLIGLEGTYIRYFNDYEPSDPETPIEFKIAKKMDPSFKTFSRRIVRYGKQYMILTRAYEKWSDTSFGMVLQRFAYEIRRFLEDVYLKTLVERLERDFNKVPNFSIRELEQIINETEVNKQMELLYNIYEEIFREIEERRTNQSSQEDFNNFMDSMKNESSLHLRLMVAFDTTVYPVPKGGAILKIFQQKILENLGDRSSVMFLKKLLNNISQDYCTMLYEWLTQGILNDPYQEFMTYDDLEGKTDNIFDTRDRAWDTQYFIRKDVLLRDCDSEEDKNLLFKMLRTGILLKVVRASLQIPTIPSNSSDITIQEINDFADLMEGSNLELYVDKCYSRANEIFLKLFFQGYDLINVLKHLQQIFLGYQSGHNVLKFLTKNMGELTKHYRNDNNANYDKLLQNFELERQSENPNNLMRQLLMIQFDTETLPQVLSHYLQIYPEVPENNSANDDSDPLMHANNFKNMNAILFDELSKERTGAYHGSNLELYTPKSAIYHLKFDINIPYPLNIIISRTCMIKYQIILRYQLVLQYHSRLLDETWMDLNKTPSWKYRGYSHTVKRRIVRATRVLHAKMNHFIKTIMEYFNQNVIDKEVYSLEKCYRNPTLAVAIQNELEGGLTNIMTNRCLSDLIPLQLQIFDIVYKFCKFIKSMRAKLCQLDPVLYEKHKSGMMKTLNEGYRTNNGGQEDVGYQEDAALELIQKLIEYISNASSIFRKCLINFTQELSTEKFDFYDSSSVDAAGIERVLYSIVPPRSASASSQR
What is the function of this protein?
Involved in microtubule organization by the microtubule organizing center, the spindle pole body (SPB).  Probably part of the microtubule attachment site at the SPB.
What are the official names of this protein?
Spindle pole body component SPC97.
What is the protein family that this protein belongs to?
Belongs to the TUBGCP family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: PDXY_PROMI
Sequence: MKNILSIQSHVVFGHAGNSXAEFPXRRMGVNVWPLNTVQFSNHTQYPEKWTGCVMXAEHITEIVDGIAAIGKLAQCDAVLSGYLGSAEQGRRIVDIVKKVKQANPNAWYFCDPVMGHPEKGCIVPPEVSGVLCEDALPISDIIAPNLLELETLAGGATLHNVDQCVKAARQLCQQGPKIVLVKHLSRAGFRHDRFEMLLVTADHSWHVSRPLVDFGERQPVGVGDLTSGLMLVDLLKGVELKTALEHVAAAVYEVMLKTKEMNEYELQLVAAQDQMVHPTHNFCATQLD
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: SYA_STAAM
Sequence: MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQMKVKSDDQVVEKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HMTB_METTH
Sequence: MELPIAPIGRIIKNAGAEIVSDDAREALAKVLEAKGEEIAENAVKLAKHAGRKTVKASDIELAVKRM
What is the function of this protein?
Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils.
What are the official names of this protein?
DNA-binding protein HMt-2, Archaeal histone A.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: HEM3_XANCB
Sequence: MTTLRIATRKSPLALWQSEHVATALRQHHPGLEVVLVPMSTRGDEVLDRSLAAIGGKGLFLKELELAMLRGEADCAVHSLKDVPMELDAPFVLPAILERGDPADALVSNLYATLQALPLGARVGTSSLRRQAQLRAARPDLELIDLRGNVNTRLAKLDNGGYDAIVLACAGLQRLGLEARITARLDAPEWLPAPAQGAVAVECRGDDARIHDLLAVLDAGRTRACVEAERAMNRALHGSCHVPVAAFARWEGEDLFLQGMVGSASDGRLIHAEAHGSPDATEDLGRRVADGLFEKGAAQLLAEL
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.