PharMolix/UniProtQA huggingface dataset:
Protein: UREE_BEII9
Sequence: MLRASSVLPRGSWHEPAADVVVLDYDARHRRRIRMRGVRGLDFLLDLENALMLRHGDAVKLDDGRLIEIVAAPEHLVEITCPDAAKLAKIAWHLGNRHLPVEFAGTKLRIRYDPVIASMLKNFSARLREIEAPFEPEGGAYAGSGQDHHDHSHGEHTQGEHTHDEAAEPHHHG
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_CUPMC
Sequence: MAQKKGGGSTRNGRDSESKRLGVKVFGGQAINAGGIIVRQRGTRVHAGENVGIGKDHTLFALVDGHVQFAVKGAAKKQQVSVVPAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: ERF1_BOVIN
Sequence: MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDIMRYVLHCQGTEEEKILYLTPEQEKDKSHFTDKETGQEHELIESMPLLEWFANNYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMEYQGGDDEFFDLDDY
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.  Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes.
What are the official names of this protein?
Eukaryotic peptide chain release factor subunit 1, Eukaryotic release factor 1, eRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
Protein: PIGN_HUMAN
Sequence: MLLFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLTTKKLRLCGKPKSHFM
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity).  May act as suppressor of replication stress and chromosome missegregation.
What are the official names of this protein?
GPI ethanolamine phosphate transferase 1, MCD4 homolog, Phosphatidylinositol-glycan biosynthesis class N protein, PIG-N.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
Protein: RL18_GEOSL
Sequence: MSPLAQKKVAHLKRKTRVRKKIRGTTERPRLNVFKSAQHIYAQIIDDTTGTTLVSASTVQKEASESLNHCGNVEAAKRVGALIAKRALEKNIATVVFDRNGFLYHGRIKALADSARENGLTF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ACYP_BURCM
Sequence: MSRNELDERIETYYVRVRGVVQGVGFRHATVREAHALKLRGWVANLEDGSVEAMIQGPGAQIDRMLAWLRHGPPAARVTEVTFEERLIERRFDRFQQQ
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: NUOH_XANC5
Sequence: MNELLLNLVDPLHQWFLGLGDGGVVLWSVLKILLIAVPVIVAVAFYVVWERKLIGWMHVRHGPMYVGMGIFQAFADVFKLLFKEIVQPTSSHKAMFVIAPLLTLAPAFAAWSVVPFDAKLVLSNANVGLLYLLAMTSLGVYGIILAGWASNSKYAFLGAMRSAAQVVSYEIAMGFALVGVMIASGSVNLSQIVFAQAGNSGFFDWFLIPLFPLFIVYWVSGVAETNRAPFDVVEGESEIVAGHMVEYSGGAFALFFLAEYANMILVSFLISIFFLGGWLSPIQGWVNADVSPWIDWLWKGGWPWLLMKVFFFASAYIWFRASFPRYRYDQIMRLGWKVFIPLTIVWIAVTALMVFYGVIQKGV
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CFT1_YEAST
Sequence: MNVYDDVLDATVVSHSLATHFTTSDYEELLVVRTNILSVYRPTRDGKLYLTDEFKFHGLITDIGLIPQKDSPLSCLLLCTGVAKISILKFNTLTNSIDTLSLHYYEGKFKGKSLVELAKISTLRMDPGSSCALLFNNDIIAFLPFHVNKNDDDEEEEDEDENIDDSELIHSMNQKSQGTNTFNKRKRTKLGDKFTAPSVVLVASELYEGAKNIIDIQFLKNFTKPTIALLYQPKLVWAGNTTISKLPTQYVILTLNIQPAESATKIESTTIAFVKELPWDLHTIVPVSNGAIIVGTNELAFLDNTGVLQSTVLLNSFADKELQKTKIINNSSLEIMFREKNTTSIWIPSSKSKNGGSNNDETLLLMDLKSNIYYIQMEAEGRLLIKFDIFKLPIVNDLLKENSNPKCITRLNATNSNKNMDLFIGFGSGNALVLRLNNLKSTIETREAHNPSSGTNSLMDINDDDDEEMDDLYADEAPENGLTTNDSKGTVETVQPFDIELLSSLRNVGPITSLTVGKVSSIDDVVKGLPNPNKNEYSLVATSGNGSGSHLTVIQTSVQPEIELALKFISITQIWNLKIKGRDRYLITTDSTKSRSDIYESDNNFKLHKGGRLRRDATTVYISMFGEEKRIIQVTTNHLYLYDTHFRRLTTIKFDYEVIHVSVMDPYILVTVSRGDIKIFELEEKNKRKLLKVDLPEILNEMVITSGLILKSNMCNEFLIGLSKSQEEQLLFTFVTADNQIIFFTKDHNDRIFQLNGVDQLNESLYISTYQLGDEIVPDPSIKQVMINKLGHDNKEEYLTILTFGGEIYQYRKLPQRRSRFYRNVTRNDLAITGAPDNAYAKGVSSIERIMHYFPDYNGYSVIFVTGSVPYILIKEDDSTPKIFKFGNIPLVSVTPWSERSVMCVDDIKNARVYTLTTDNMYYGNKLPLKQIKISNVLDDYKTLQKLVYHERAQLFLVSYCKRVPYEALGEDGEKVIGYDENVPHAEGFQSGILLINPKSWKVIDKIDFPKNSVVNEMRSSMIQINSKTKRKREYIIAGVANATTEDTPPTGAFHIYDVIEVVPEPGKPDTNYKLKEIFQEEVSGTVSTVCEVSGRFMISQSQKVLVRDIQEDNSVIPVAFLDIPVFVTDSKSFGNLLIIGDAMQGFQFIGFDAEPYRMISLGRSMSKFQTMSLEFLVNGGDMYFAATDADRNVHVLKYAPDEPNSLSGQRLVHCSSFTLHSTNSCMMLLPRNEEFGSPQVPSFQNVGGQVDGSVFKIVPLSEEKYRRLYVIQQQIIDRELQLGGLNPRMERLANDFYQMGHSMRPMLDFNVIRRFCGLAIDRRKSIAQKAGRHAHFEAWRDIINIEFSMRSLCQGK
What is the function of this protein?
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Involved in poly(A) site recognition.  May be involved in coupling transcription termination and mRNA 3'-end formation.
What are the official names of this protein?
Protein CFT1, Cleavage factor two protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2163_DICDI
Sequence: MTSVSSDSRKQFKGSGDHVFDFDNKENHDFLSLTIKQDNNNNNNNNTNVSLSPSIKSQATSSTGGNKNQIFSQMRELDKKSLMLIETYYRDKLITYQEKLKRELEQIYNKKLQSLKIQYDSDSYLKFKQFELETKKALLLLLKEFQDLKKSKQQQEKQLKLQQIKQESNNNNNNNNNNNNNNNNNNNNNNNNDDDQQKDIDNSNDIVNDFKTDKILKEKEEILNKLELITKSITDLFIQQVDISTDTIDFQSFLSNIVATTTTTTATISN
What are the official names of this protein?
Uncharacterized protein DDB_G0293860.
Protein: SPG21_PONAB
Sequence: MGEIKVSPDYNWFRGTVPLKKIIVDDDDSKIWSLYDAGPRSIRCPLIFLPPVSGTADVFFRQILALTGWGYRVIALQYPVYWDHLEFCDGFRKLLDHLQLDKVHLFGASLGGFLAQKFAEYTHKSPRVHSLILCNSFSDTSIFNQTWTANSFWLMPAFMLKKIVLGNFSSGPVDPMMADAIDFMVDRLESLGQSELASRLTLNCQNSYVEPHKIRDIPVTIMDVFGQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVNLYVQIHLLQFHGTKYAAIDPSMVSAEELEVQKGSLGISQEEQ
What is the function of this protein?
May play a role as a negative regulatory factor in CD4-dependent T-cell activation.
What are the official names of this protein?
Maspardin, Spastic paraplegia 21 autosomal recessive Mast syndrome protein homolog.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_RICCK
Sequence: MPKLKTKSAAKKRFKLTASGNVIASQAGKKHFMRRRTKAQIRNLRGTTILCNQEGYNIKKYFLPYGTN
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: IOLG_SINFN
Sequence: MTLRVGVIGTGMIGQDHIRRLTQVLSAVEVVAVSDIDGARAAAVAPQGADVYAAAGDLIRSETVEAVVICSWGPAHEEQLLDCIAAGKPVFCEKPLVTTAAAALRVMEAEVAFGRRLVQVGFMRRFDADYRRLKATLDAGVLGAPLMFHSTHRNASVPEGLYTSDMPLNDTLVHDAYISRWLLNDEVTGVEVRVPRRSRRGGELRDPVVVLLHMGSGALVDVEISVNIAYGYDIRGEVSCEEGTASLPLRPATVIRDIHGVRQPVPADWRERFIEAYDQEFREWIVAAAQGTATGPSTWDGYAATLVADAALRAAESGALEPVRMCQRPSLYGPTLEAAR
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: PCY2_MOUSE
Sequence: MIRNGHGAASAAGLKGPGDQRIVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKHNCDFCVHGNDITLTVDGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKPPHPTPAGDTLSSEVSSQCPGGQSPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLQEVHKLAKRPYVIAGLHFDQEVNRYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYSVTAELLNHFKVDLVCHGKTEIVPDRDGSDPYQEPKRRGIFYQIDSGSDLTTDLIVQRIIKNRLEYEARNQKKEAKELAFLEATKQQEAPPGGEID
What is the function of this protein?
Ethanolamine-phosphate cytidylyltransferase that catalyzes the second step in the synthesis of phosphatidylethanolamine (PE) from ethanolamine via the CDP-ethanolamine pathway (PubMed:17325045).  Phosphatidylethanolamine is a dominant inner-leaflet phospholipid in cell membranes, where it plays a role in membrane function by structurally stabilizing membrane-anchored proteins, and participates in important cellular processes such as cell division, cell fusion, blood coagulation, and apoptosis (PubMed:17325045).
What are the official names of this protein?
Ethanolamine-phosphate cytidylyltransferase, CTP:phosphoethanolamine cytidylyltransferase, Phosphorylethanolamine transferase.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
Protein: DTML_BURP1
Sequence: MGNGERPPARRPDSSGSPPPAADAPAASNHPFSSHDTKHMTSRRLASRTAVAASLSALMLAACGGDDSANAPTAGGAAPLTPAVASPAGPTGSTPGSTPGATTAPAPSSTSAGQLSVDKMAFAQTHVVPSGGLSWTLPNASASLRPISRRDALVLVAIGQADAVQPVLEAWKDGAKLGALALSPPSALPPTESGGRAYANDRWSAVVPAAWMVPGVSFSVSASNYTSSVAQAPVFGTDADVQLTILPFYLFGADDTNSPPLSTTQAPDAATQQEIFAKWPTAELKVRTHPAGRFSLATVVVGPRADRTGAAQPAYPVTALDQQKDGYGVMSAMLTLITNMRTANGDGPLNNQYYAPLIALNSNGQFANLGGGLGGVGSGAAVGDHRYTGIFIHEQGHAFGLNHAGDEYAKGAYPYAGGSLSGSVWGYDPNHREFLDVLVPTTASSYAKCASSHQLDAQGRCYKQDPMQGGAGDQSSGYKFATFSDYNTGRMQAWIASRVLADPASSTGYSKWDSAAQARAPYTPTTDNNGLYGVNQNLPVQAGVPVHTIVVSFSKAGSAGASYIYPPFSYTGNLIATFDPTSAADRQAITVDKGTYPWYCKGTGCDYTLRVTYADGSRTYRVLQGGFRAWWTPTVDDANATNPLSGSSFRVWAINVPGDKRIGKIELLDTPMVWNGMPANPTVLLSR
What are the official names of this protein?
Dictomallein.
What is the protein family that this protein belongs to?
Belongs to the dictomallein family.
Protein: TM1L1_HUMAN
Sequence: MAFGKSHRDPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQKEATNTTSEPSAPSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPSLHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAVTTEAIYEEIDAHQHKGAQNDGD
What is the function of this protein?
Probable adapter protein involved in signaling pathways.  Interacts with the SH2 and SH3 domains of various signaling proteins when it is phosphorylated.  May promote FYN activation, possibly by disrupting intramolecular SH3-dependent interactions (By similarity).
What are the official names of this protein?
TOM1-like protein 1, Src-activating and signaling molecule protein, Target of Myb-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TOM1 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack. Endosome membrane. Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Note=A small proportion is membrane-associated.
Protein: ARGC_EHRRG
Sequence: MSYQVSVAVVGATGYVGVELVRLLLFHPMVKIKYLCATQSIGSLLSSHYDHVLKDSIPVSISCFSSIDLSKVDVIFLCLPHGQSNEIVKKIHNEVKIIIDLSADFRIKDIDTYKEWYGAHCCPDLIQDFVYGLTEIYWEEIKKSRFVACPGCYATSALVPLFPLLRLRLVKSQNIIVDAKSGVSGAGRSVDQKKLFCEIHDVIKSYNISKHRHIPEIEQELCFAACQENINVQFVPNLIPVKRGMLSSIYLELEEGVSPIDIREALLVFYKDSKFIFIDEEKAITTKSVIGTNYCYIGVFPGRIPNTVIIVCNIDNLLKGASGQAVQNFNIMMSCDETTALLNIPYL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEUP1_HUMAN
Sequence: MENQAHNTMGTSPCEAELQELMEQIDIMVSNKKMDWERKMRALETRLDLRDQELANAQTCLDQKGQEVGLLRQKLDSLEKCNLAMTQNYEGQLQSLKAQFSKLTNNFEKLRLHQMKQNKVPRKELPHLKEEIPFELSNLNQKLEEFRAKSREWDKQEILYQTHLISLDAQQKLLSEKCNQFQKQAQSYQTQLNGKKQCLEDSSSEIPRLICDPDPNCEINERDEFIIEKLKSAVNEIALSRNKLQDENQKLLQELKMYQRQCQAMEAGLSEVKSELQSRDDLLRIIEMERLQLHRELLKIGECQNAQGNKTRLESSYLPSIKEPERKIKELFSVMQDQPNHEKELNKIRSQLQQVEEYHNSEQERMRNEISDLTEELHQKEITIATVTKKAALLEKQLKMELEIKEKMLAKQKVSDMKYKAVRTENTHLKGMMGDLDPGEYMSMDFTNREQSRHTSINKLQYENERLRNDLAKLHVNGKSTWTNQNTYEETGRYAYQSQIKVEQNEERLSHDCEPNRSTMPPLPPSTFQAKEMTSPLVSDDDVFPLSPPDMSFPASLAAQHFLLEEEKRAKELEKLLNTHIDELQRHTEFTLNKYSKLKQNRHI
What is the function of this protein?
Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells.  Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles.  Probably sufficient for the specification and formation of the deuterosome inner core.  Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity).
What are the official names of this protein?
Deuterosome assembly protein 1, Coiled-coil domain-containing protein 67.
What is the protein family that this protein belongs to?
Belongs to the CEP63 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the deuterosome.
Protein: RNQ1_YEAST
Sequence: MDTDKLISEAESHFSQGNHAEAVAKLTSAAQSNPNDEQMSTIESLIQKIAGYVMDNRSGGSDASQDRAAGGGSSFMNTLMADSKGSSQTQLGKLALLATVMTHSSNKGSSNRGFDVGTVMSMLSGSGGGSQSMGASGLAALASQFFKSGNNSQGQGQGQGQGQGQGQGQGQGSFTALASLASSFMNSNNNNQQGQNQSSGGSSFGALASMASSFMHSNNNQNSNNSQQGYNQSYQNGNQNSQGYNNQQYQGGNGGYQQQQGQSGGAFSSLASMAQSYLGGGQTQSNQQQYNQQGQNNQQQYQQQGQNYQHQQQGQQQQQGHSSSFSALASMASSYLGNNSNSNSSYGGQQQANEYGRPQQNGQQQSNEYGRPQYGGNQNSNGQHESFNFSGNFSQQNNNGNQNRY
What is the function of this protein?
Transferable epigenetic modifier which forms a prion responsible for the non-Mendelian trait [PIN+].  The native function of the soluble protein is unknown.
What are the official names of this protein?
[PIN+] prion protein RNQ1, Rich in asparagine and glutamine protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TIG_STRAW
Sequence: MKSAVETLNPTRVRLTVEVPFEELKDSLDAAYKKINQQVTVKGFRKGKIPARVIDQRFGRGAVLEEAVNDALPKFYTEAVNEAELNPLGQPEVDITELKDGETLNFTAEVDVRPTIEIPDYSGIEVEVDAVEVSDEDVEKAVTELRERFASTSPVERAAEDGDVVTLDLEAKVDGEVLEDGVAEGVSYTIGSGELLDGIDDAVKGLEAGGETTFTSELKGGSAAGKEAEVTVKVSQVAARELPELDDDFAQLASEFDTLEELKADSRKRLENMKQYDQATQAQERVLEKLLELAEVPVPEKLLEDEINTRKHNLEHHQLGQMGLDLEKYLEIQGKTVEEFDAETKEAAVKGIKTQFVLDELVNKEKLNVNQEELTEHLMRRAASSGMSPDQFAQAVVEGGQVPMLVGEVARGKALAVVVEAATVKDTNGEIVDLDDEDETESTPETTEAAEAAEESTEDKPEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PRORY_HUMAN
Sequence: MMRRSPSGLKSPRVSQGRKPRDPESLLFLRCCLGSEPHNLSSLLSPEAGQEPLPKLLPQPLAGHAAWGIHGVPTSLLLAGECWGQGMAVPADPPPASPYRTSPRPPPGPLPRYRPQQHLLLPLGRLHALCPGCPLQQSLQFERGTLSAPRLWSWMKLETIILSKLSQGQKTKHRMFSLISES
What are the official names of this protein?
Proline-rich protein, Y-linked.
Protein: ROL3_CAEBR
Sequence: MLDFPRFSLFLFLLFSSFLFSSFVHAATVFSSSLKTCQSQCEERNLAYPLDSGEVHWTGLAEFNYTTRISSCKHGCEDVDERESKCNVKCAEEGIVTNSCKQGCRAVLVSFLAQAQALLIQTRVNMEVLETAMKLKWEFPETLAEELKEIANADIFWFSQTRPLNGILGWRWTSLPQSSFRNSSLVSEVHVPFEHGEHVEVRLALSYRNQVLVSRTTTYHLPLSKAGTTLEVIGQLQLSDDRVAVCYRTNQPTPKFKLTVMTMDDNTINTEESISRCHLFSNLPRDNCCKASISAIDEHGATTAFVEIKLDFFVNQVEIELVSAASSSRIIFSNGTHLLENEELAQYALGDSATVIPFPLPTDDTITAIAGITDTIIAIGSSKGSLWTFQMSANQTDEDQPSSVIQLKTVGEMDTKITQIEIDHIQRTLYAVQHDKGILRCKLRTMESEESPTCVLIVNNDALNPPKEITLDPVNGHIYSLNVDNKVYRTEMIAFNATGIETVASLQYLKDMSPSNGIFFDVSKFLLYSALQNGSMMTLNPVTDQAHIFKDSGYTDVQNFRIKSDLIYWMKKKCGKTDADENCIFTENLQRSEEDIPNKFTYSSALMSYSFLEEILLKPRIVAVSSIALLTSDKTGRVSWDEANTLPFQAQGSSWRNFTYFLKITAPDITDFEAVEMYTSSTDVKIDVTPGNQYNAQVQVCSDDFCSTPSSTSNTALPDLGGGVPFVFTKKKADDIISIDMLGNLVITDDSVKAVERMQNPHVLDNTTKTVYLAGDHSMGIFKKDLDDATGSPKPFKDGLFVEMMSIMPSRSMILIASSYKITSYRLPTTFDFEYYSCEEPLEDCAEVMGISSDDSTGMVYFLTQSRNGTVILWESDPENRAPRDIATAPSIVPFRRFLIIHDKMILVTKNNHIVQTDKSLKVVNVATELERVDRILPLRYAAISHKIEFTDEIKFMEGSKTDLQWTLSPPLEAGTVIFKVSFFREKMGGQDAPITTIQSDTNFTIPPEVLKEWSSAQRFDVSIQAITPWATAVLNRTGLTAPVKPPTPPTQLKIFATQQKTVDGPRALISFFWGPPLEWNGTPYQYIVNCTKDDGKVITIDSSELKPLVKLFAIDSTNSLIIINDLAHEEPRRETRQVTQPVKLDYQAMAFIGEDLYTVRKEGESAQPFLVQIDTNHIDNTVHKVSIGGDVTRIDAMTSDWVGNRLIFVAGTNLYQLSLEPFLSTSLLNPHKLITLSAATDAKQLAYDPFMNTAYLLTKNGSLFALDMNKNTEANLALTVPCLASQTVTWMMTEFAWNRASSPKIYALTWNGLINVDLAEDFQCNEVRIDWSKFGEKGLKAISSFAIADKLFAFVTSSEMLIYGRDTVTPITIANPPLKQILAVSQSSQPYPERSCFELPSSKGIVFSIVNEGKTGALLEVTKSSSSSACLDVSMPQTQYEIYFTRKNTDKVKHVRSFSDRIHVENGILDKETDYDVTVTWLNRYSPASGVSSSRSFRTGFGYPSAPRDPHAIPVTPDTVYLYWSLPETLNAPISEIKYKISQQAAGISVPTSIAVIPLSETVSSNISSDTTACLINPCRVKIANLRPSNEYKFWVTATHISHLDAATILKDDDAVSSEAVARTLDVPGTLRPDNVTGSSLLLRWNGLEPEHRPTSIAIQYRESGGANNEWQSPTNASFEPDVATELVPVTNLLSATTYDYRFVATYTGTYTIDGKVLAFKEDYLQLIQQARTKAGVPTAPQSVEAKIDTEGWIVTWKEPMSDGGSPITSYAVETRINKTAEWEIAERGLDGWKTWWRPGKSETSSSMSYSSEVSEFRIRAANIEGFGAYAYTEEKKEEKEEEKGGILPYFLGISIILLLAAMILVGCFWLKSRRRQQMKKREAEDERNCIRLDVVANMNFTNSRQTLSPEYESEIRNLPIVDYNDVEIVRHISDCSYGSVHEGIAEEVPLSWEKQVKVAVKQLRPKSANHDFDRMMFMKEAILLNNLDHNIVKELGVCVSPGQGLILLEYMEGGNLLNFLRESAPSEMQASELSTRDLLAISVDIARGMNYLERLPHVHKNLSARKCLLSGRPGVAKLEMGMPRALSKGEINRVDLESMQSVKWMAPEVFKDLMFTSKSDVWAYGVLLYEIFSFGEEPYGSMDSRRVITDVRDGNLTLPVPPYCPSKKICKVMKMCLISDPNKRASFATILKIFETCRDDQQSQDDKRIHFNEGSDNINFNASQDSTSSREPPSPSHRIREFTQISGDLEPPSPSPLNQSFGGFEHPYEGDRPATMWNASGARNSAKNSIGRSMKKDKFRNPIHSMDDLVARSQRPLSIHSEDTESTDFGGATSSMHSPSSSNRTNHYELPMSRLSAAPPIGIVNNAFESSNNSLNMSRSWTGLAGEVNPNPAGASSSGTLPHHANSMVHLRAPTGQPPTRVNRNSSGGTCRSVSQV
What is the function of this protein?
Involved in larval development and locomotion.
What are the official names of this protein?
Protein roller-3.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NADE_ECO5E
Sequence: MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREACIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGTDHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEGKNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: CLGN_MOUSE
Sequence: MRFQGVGLCLGLLFITVNADFMDDGVEVEDFSENSDESNIKDEPSSGTFKYKTPQPIGEVYFTETFDSGNLAGWVLSKAKKDDMDSEIAIYDGRWEIEELKENQVPGDRGLVLKSKAKHHAIAAVLEKPFIFADKPLIVQYEVNFQDGIDCGGAYIKLLADTGDLILENFYDKTSYTIMFGPDKCGEDYKLHLIFRHKHPKTGVFEEKHAKPPDVDLKEFFTDRKTHLYTLVMNPDDTFEVLIDQKVVNQGTLLDDVVPPINPPREIDDPSDKKPEEWDDRAKIPDPTAVRPEDWDENEPAQIEDSSAVKPDGWLDDEPKFIPNPKAEKPEDWSDDMDGEWEAPHIPNPACQIGCGEWKPPMIDNPKYKGIWRPPMINNPNYQGLWSPQKIPNPDYFEDDHPFLLTSFSALGLELWSMTPDIYFDNFIICSEKEVADQWATDGWELKIMVANANEPGVLRQLVIAAEERPWLWLMYLVMAGLPVALVASFCWPRKVKKKYEDTGPKKTELCKLQSKAALEQEAEEEKAPEKPEDVQEEKKPGEAEVVTVEKEVIGEPEEKSKEDRETLEGQEEVSKLSKSGSEDEMKDADESPGSGDAPLKSLRKRRVRKD
What is the function of this protein?
Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida.  Required for normal sperm migration from the uterus into the oviduct.  Required for normal male fertility.  Binds calcium ions.
What are the official names of this protein?
Calmegin, A2/6, Calnexin-T, MEG 1 antigen.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: YFSA_SCHPO
Sequence: MYTSASLFFIQIVISIFNSHLAVLYSIALCYSVQGRILGSSTTNFVHDSTIGVKSSWSRHLIHGINIFSFSISLFLIFLTIPLFDIG
What are the official names of this protein?
Uncharacterized protein C19D5.10c.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.