PharMolix/UniProtQA huggingface dataset:
Protein: EFG_BUCAP
Sequence: MSRTTPICQYRNIGISAHIDAGKTTTTERILFYTGINHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWSGMAKQFKPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWRQANKYNVPRIAFINKMDRMGANFLRSVKQIKTRLGGNPVPLQLPIGSEENFKGVIDLIKMKAIKWKDIDQGITFTYDEIPSDMIELSEKWHQNLIESAVESNEELMEKYLSGFVLSEKEIKSELRKRSLNNEITLITCGSAFKNKGVQALLDAIIEYLPAPNDIQDIKGITNDKASTVAFRSSNDKAPFSALAFKIASDPFVGNLTFFRVYSGIVKSGDSVLNSVKSQRERFGRIVQMHANKREEIKEVYAGDIAAAIGLKDVTTGDTLCDLNQPIILERMEFPEPVISISVEPKTKADQEKMGLALARLAKEDPSFRVRTDQESNQTIISGMGELHLEIIVDRMKREFSVDANVGKPQVAYRETILNKVTDIEGKHIKQSGGRGQYGHVVIELFPLESGGKGYLFVNDIKGGVIPNEYISAIDKGIQEQLKYGPLAGYPVVDIGVRLYFGSYHDVDSSELAFKLAASLAFKNGFKKAKPILLEPIMKVEVETPDDYMGDVIGDLNRRRGIIEGMKDLEIGKIINACVPLSEMFGYATDLRSQTQGRASYSMEFLKYVEAPSVISDLIIQKRER
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB3C_HUMAN
Sequence: MRHEAPMQMASAQDARYGQKDSSDQNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVISTERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQNTRLKETPPPPQPNCAC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab-3C.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: INVO_PANPA
Sequence: MSQQHTLPVTLSPALSQELLKTVPPPVNTQQEQMKQPTPLPPPCQKMPVELPVEVPSKQEEKHMTAVKGLPEQECEQQQQEPQEQELQQQHWEQHEEYQKAENPEQQLKQEKAQRDPQLNKQLEEEKKLLDQQLDQELVKRDEQLGMKKEQLLELPEQQEGHLKHLEQREGQLELPEQQEGQLKHLEQQKGQLELPEQQEGQLELPEQQEGQLKHLEQQEGQLKHLEHQEGQLEVPEEQVGQLKYLEQQEGQLKHLDQQEKQPELPEQQVGQLKHLEQQEGQPKHLEQQKGQLEHLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVQQLKQLEKEEGQPKHLEEEEGQLKHLVQQEGQLEHLVQQEGQLEHLVQQEGQLEQQEGQVEHLEQQVEHLEQLGQLKHLEEQEGQLKHLEQQQGQLGVPEQVGQPKNLEQEEKQLELPEQQEGQLKHLEKQEAQLELPEQQVGQPKHLEQQEKQLEPPEQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQSALPTKGEVLLPLEHQQQKQEVQWPPKHK
What is the function of this protein?
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
What are the official names of this protein?
Involucrin.
What is the protein family that this protein belongs to?
Belongs to the involucrin family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Constituent of the scaffolding of the cornified envelope.
Protein: GGGPS_HYPBU
Sequence: MKLGKVERLLRSRVESGEKLFLLLSDPEKPISPNTVKLFEENGADVLLIGGSLNVTPYDIDEYIARLRVEGVKLPIVLFPGGLNNIAKSADAILFMTLMNSMDPYWIVGAQVAAAPIVYRLGLEAIPSAYIIVGHGGAAGHIGRALPIPYENGYIAAAYALAAEYLGARLVYFEAGSGAPKPVPVDAVAAASKVLSQALLVVGGGIREETLAAERLKAGADGVVIGTLAEKDPEKALRSSR
What is the function of this protein?
Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).  This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
Geranylgeranylglyceryl phosphate synthase, GGGP synthase, GGGPS, (S)-3-O-geranylgeranylglyceryl phosphate synthase, Phosphoglycerol geranylgeranyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPPRC_MOUSE
Sequence: MAALLRPARWLLGAAAAPRLPLSLRLPAGVPGRLSSVVRVAAVGSRPAAGERLSQARLYAIVAEKRDLQEEPAPVRKNSSQFDWALMRLDNSVRRTGRITKGLLQRVFESTCSSGSPGSNQALLLLRSCGSLLPELSLAERTEFAHKIWDKLQQLGVVYDVSHYNALLKVYLQNEYKFSPTDFLAKMEGANIQPNRVTYQRLIAAYCNVGDIEGASKILGFMKTKDLPITEAVFSALVTGHARAGDMENAENILTVMKQAGIEPGPDTYLALLNAHAERGDIGQVRQILEKVEKSDHYFMDRDFLQVIFSFSKAGYPQYVSEILEKITYERRSIPDAMNLILFLATEKLEDTAFQVLLALPLSKDESSDNFGSFFLRHCVTLDLPPEKLIDYCRRLRDAKLHSSSLQFTLHCALQANRTALAKAVMEALREEGFPIRPHYFWPLLAGHQKTKNVQGIIDILKIMNKVGVDPDQETYINYVFPCFDSAQSVRAALQENECLLASSTFAQAEVKNEAINGNLQNILSFLESNTLPFSFSSLRNSLILGFRRSMNIDLWSKITELLYKDERYCSKPPGPAEAVGYFLYNLIDSMSDSEVQAKEERLRQYFHQLQEMNVKVPENIYKGICNLLNTYHVPELIKDIKVLVDREKVDSQKTSQVTSSDLESTLEKLKAEGQPVGSALKQLLLLLCSEENMQKALEVKAKYESDMVIGGYAALINLCCRHDNAEDAWNLKQEVDRLDASAILDTAKYVALVKVLGKHSRLQDAINILKEMKEKDVVIKDATVLSFFHILNGAALRGEIETVKQLHEAIVTLGLAKPSSNISFPLVTVHLEKGDLPAALEASIACHKKYKVLPRIHDVLCKLVEKGETDLIQKAMDFVSQEQGEMTMLYDLFFAFLQTGNYKEAKKIIETPGIRARPTRLQWFCDRCIASNQVEALEKLVELTEKLFECDRDQMYYNLLKLYKISSDWQRADAAWTKMQEENIIPRERTLRLLAEILKTSNQEVPFDVPELWFGDDRPSLSPSSRSAGEDVTEKTLLSNCKLKKSKDAYNIFLKAEKQNVVFSSETYSTLIGLLLSKDDFTQAMHVKDFAETHIKGFTLNDAANSLLIIRQVRRDYLKGALATLRAALDLKQVPSQIAVTRLIQALALKGDVESIEAIQRMVAGLDTIGLSKMVFINNIALAQMKNNKLDAAIENIEHLLASENQAIEPQYFGLSYLFRKVIEEQMEPALEKLSIMSERMANQFALYKPVTDLFLQLVDSGKVDEARALLERCGAIAEQSSLLSVFCLRTSQKPKKAPVLKTLLELIPELRDNDKVYSCSMKSYALDKDVASAKALYEYLTAKNLKLDDLFLKRYAALLKDVGEPVPFPEPPESFAFYIKQLKEARESPS
What is the function of this protein?
May play a role in RNA metabolism in both nuclei and mitochondria.  In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export.  May bind mature mRNA in the nucleus outer membrane.  In mitochondria binds to poly(A) mRNA.  Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits.  May be involved in transcription regulation.  Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors.  Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP.  Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters (By similarity).  Binds single-stranded DNA.
What are the official names of this protein?
Leucine-rich PPR motif-containing protein, mitochondrial, 130 kDa leucine-rich protein, LRP 130, mLRP130.
What are the subcellular locations of this protein?
Mitochondrion. Nucleus. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus outer membrane.
Protein: RPOB_COXBU
Sequence: MAQANSRSRNSATISYPEKRRARVNLGKREVEILKTPYLLETQIESYRKFLQKDIAAEKREDNGLHAAFKSVFPITSYSGYAVLEYVGYSLGGESTLFDVEECKLRGLTYAAPLKVNMRLVIYDKEAPAGKKAIKDIKEQEVYMGEIPLMTETGSLVINGTERVVVSQLHRSPGVFFEHDKGKTHSSGKLLYSARVIPYRGSWLDFEFDPKDCLFVRIDRRRKLPATVILRALGYDTEQILDMFYKTNHFHLNQETVTLDLIPQRLRGELAVVEIKDKKGKVIVEANRRISARHIRLIEKAEINKLELPDDYLYGKVIGKTIIDKETGEIIAHANEEITAELLKNLRATKTASLDTLYINEIECGPYVSDTLRLDTTTNQLEALVEIYRIMRPGEPPTKEAAESLFENLFFSPERYSLSAVGRMKFNRRVGRKELTGLDVLSKEDIVDVLRVLVDIRDGKGDVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKDRLSLADVENLMPQDLVNAKPVSAAIKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHVTHYGRVCPIETPEGPNIGLINSLAVFARANEYGFLETPYRKVVDRVVTDETEYLSAIEEGDYYIAQANTNVDEKGRLVDDLISCRYKGEFTLTTPDKINYMDVSPRQIVSVAAALIPFLEHDDANRALMGSNMQRQAVPTIRPETPLVGTGMERTVAVDSGVTVIAKRSGVIDSVDASRIVVRVDRKETEDDDDIGVDIYNLTKFTRSNQNTCINQHPIVEVGDKVQKGDVLADGPSTDIGELALGQNLLVAFMPWNGYNFEDSILISERLVEEDRFTTIHIQEFTCVARDTKLGPEEITSDIPNVGESALAKLDESGIVHIGAEVNAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVTPGITGTVIDVRIFTREGIKKDERTLEIEKAELSKVEKDLNDELRVREDALFENLEKLLTGRVAAGGPNKLAKGTKITKSYLADLPRQKWFEIRLQDDAATKRLEASHEHFKELRETRDAKLKDSRQKLTQGGDLAPGVIKIVKVYLAVKRRIQPGDKMAGRHGNKGVISTIVPIEDMPYLEDGTPVDIVLNPLGVPSRMNIGQVLETHLGWAAKGLGKKIGEMIEKGADAKELRKSLKPIYDLSKTQRFDLEALEDPEIVTLAKNLRKGVPISSPVFDGATEEEIKQLLKMADLPTSGQAALYDGRTGKKFDRSVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTRMYKNIVDGDHRMDAGMPESFNVLVKEIRSLAIDIGLEND
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RECO_STRGC
Sequence: MMQSITSKALVLYNRNFREDDKLVKIFTEQAGKRMFFVKHATNSKLSPVIQPLTLANLLMKVNDDGLSYIQDYQDVQPFTRINSDLFIMAYATYVAALADASIPDSQPDAALFAFLTKTLELMEEGLDHEILTNIFEVQILSRFGVSLNFHECVFCHRTGLPFDFSFKFSGVLCPDHYREDDRRCHLHPNIPFLLDQFQAVEYSTLETISLKAEIKQQLREFIDQIYDDYVGIHLKSKKFIDSLGDWGSILKDKENKESI
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RL1_SOLM1
Sequence: MAKHGKNYREAIKDIDLTAKYEVSEAMALTVQTGKAKFDETVDVALNLGVNPKYSDQMVRGAVSLPHGLGKTIRVAAFCKGDKETEAREAGADFVGGDDLIEKVKNGFLDFDSAVATPDMMASVGKIGKILGPRGLMPNAKTGTVSFDIGKAVSELKAGKVEFKVDKAGVLHVPLGKRSFGPEKLLDNFRAVIDAVMRLKPSAAKGTYLQAMALATTMGPGIKVDTQSVRKLLEG
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: DNAK_LISMH
Sequence: MSKIIGIDLGTTNSAVAVLEGGEAKIIPNPEGARTTPSVVGFKNGERQVGEVAKRAAITNPNTISSIKRHMGTNYKETIEGKDYSPQEISAIILQYLKSYAEDYLGETVDKAVITVPAYFNDAQRQATKDAGKIAGLEVERIINEPTAAALAYGMDKTETDQTILVFDLGGGTFDVSILELGDGVFEVHSTAGDNELGGDDFDKKIIDYLVAEFKKDNGIDLSQDKMALQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEVTLTRAKFDELTHDLVERTIAPTRQALKDANLSASDIDQVILVGGSTRIPAVQETIKKELGKEPHKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVMTTLIERNTTIPTSKSQTFSTAADNQPAVDIHVLQGERPMAKDNKTLGRFQLADIPAAPRGIPQIEVSFDIDKNGIVTVRAKDLGTGKEQNIVIKSSSGLTDEEIEKMVQDAEANAEEDKKNKENAELRNNADQLVFTVDKTLKELEGKVEEEEVKKAEAARDELQEALKGEDFEAIKEKTESLNEIVQNLSVKLYEQAAAEQQAAGGAEGQEAPQNDDVVDAEFEEVNDDDKENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: Y3701_ARATH
Sequence: MGKSSNIVFDRIKEERQMLSFFKIFQRADLSSDCMRALPYSFISKVSEKDFSYKMVIRAQWGKTWDVEVSKNPTYYYIETRGWDLFVSDNALGQNEFITFTHRGNMVFHVNIYEQNGLEMRKPRKFQTMGPSSGIKKEEGENSLIDVKKEEESDESPGRAEFLVRKKKTEDSKSSKKKMTRNKVKKKSKSKSKQVLDGVPEFKITIRKSYLKFLAIPKHFVDDHIPNKSKIFTIRHPNGGSWKVLCLVREIRTIFSGGYSKLAREFPLMVGDKCTFKLIKPFEFVLLTSKKNREKMDQCMID
What are the official names of this protein?
B3 domain-containing protein At3g17010.
What are the subcellular locations of this protein?
Nucleus.
Protein: SURE_PSELT
Sequence: MKILLTNDDGVTSQGLLILAKVLSQKHNILVVAPESEQSATGHAITVRMPIWVKRVRVLEEFPIYATTGTPADCVKIGMEVLANKQIDMVISGINIGHNLGTDVIYSGTVSGALEGALLGVPSIAVSAPARENFDYYSASFFISNFIENFDFSILEPFTALNINFPEGDIKGWKATRQSIRRYADRFEARTDPSGNTYYWMYGDVVEDDSATDCDYCVVSKGYVSVTPITVFMLNERALLQLKEVENGKENKTSWRSGS
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CALM5_ARATH
Sequence: MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIKEADVDGDGQINYEEFVKVMMAK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin-5, CaM-5.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: MIAA_GLUOX
Sequence: MNAPKTVTVKTALIVAGPTCSGKSALALDLARCFEGTVINADSMQVYRDLHILTARPHAADEAAVPHRLYGVLDAAVPGSVAWWRSEALREMDVAWAEERMPILCGGTGMYLRALTDGLVEVPDPGDAARSEARGLAEEIGPEALHARLMQVDPETASGLRPNDTQRISRAWEVWTGTGHGLAWWRSQPGLPPASCRFVSVQLDPEREGLRRAIDSRFGQMLEAGALEEVSALLERGLDPVLPAMRAHGVPELAAVLRGEVPLEEARKSAVLAIGRYTRRQATWFRHHALGKGDDGMISLRRYTHSAQESESQYEKIENFISERVDAAARAS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: FBXW7_BOVIN
Sequence: MNQELLSVGSKRRRTGGSLRGNPSSSQADEEQMNRVLEEEQQQPRHQEEEHAARNGEVVGAEPRPGDQNDPQQGQLEENNNRFISVDEDSSGNQEEQEEDEEHAGEQDEEDEEEEEMDQESDDFDQSDDSSREDEHTHRNSVTNSNSIVDLPIHQRSSPFYTKTTKMKRKLDHGSEVRSFSLGKKPCKVSEYTSTTGLVPCSATPTTFGDLRAANGQGQQRRRITSVQPPTGLQEWLKMFQSWSGPEKLLALDELIDSCEPTQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWRILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQHRIDTNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTSTVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter brings them to the SCF complex for ubiquitination (By similarity).  Identified substrates include cyclin-E (CCNE1 or CCNE2), DISC1, JUN, MYC, NOTCH1 released notch intracellular domain (NICD), NOTCH2, MCL1, RICTOR, and probably PSEN1.  Acts as a negative regulator of JNK signaling by binding to phosphorylated JUN and promoting its ubiquitination and subsequent degradation (By similarity).  SCF(FBXW7) complex mediates the ubiquitination and subsequent degradation of NFE2L1 (By similarity).  Involved in bone homeostasis and negative regulation of osteoclast differentiation (By similarity).  Also able to promote 'Lys-63'-linked ubiquitination in response to DNA damage (By similarity).  The SCF(FBXW7) complex facilitates double-strand break repair following phosphorylation by ATM: phosphorylation promotes localization to sites of double-strand breaks and 'Lys-63'-linked ubiquitination of phosphorylated XRCC4, enhancing DNA non-homologous end joining (By similarity).
What are the official names of this protein?
F-box/WD repeat-containing protein 7, F-box and WD-40 domain-containing protein 7.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Chromosome. Note=Localizes to site of double-strand breaks following phosphorylation by ATM.
Protein: RS8_TREDE
Sequence: MSVSDPIADMLTKIRNAASAGHESVDVPSSKMKWEIISILKSEGYIKNFKKMTQEGAGNIRVFLKYDDKESSVIHGIERVSTPGRRVYLGYKSLPRVFNGYGTLIVSTSKGIITGKAAGESQVGGELICKVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL2_RUBXD
Sequence: MPARRYKPTSPGRRNSSVLTRDSVTKEKPEKSLLAKLHKTGGRNVHGRITTRHKGGGHKRRYRIIDFKRNKDGVPATVAAIEYDPNRSANIALLHYHDGEKRYILAPRNLTVGSVVMSGPEAEVDVGNALPLANIPVGTTVHAVELEPGRGAQLARSAGTSAQIIAREGNLVTLRLPSGERRRVRAECRATVGVVGNQSHQNVRWGKAGRKRHLGIRPTVRGTVMNPVDHPHGGGEGKSTPGRAPVTPWGKITQGKPTRKKRKRSDAMIVARRKKGRRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PHS_XYLFT
Sequence: MNDRITLAQAHCQPREKKEHKLGQARLAELLTQVPGWELSNNGHALTRTFQFDNYYRTLAFVNALAFIAHCEDHHPDMNVHYGRAVVCFSTHKIGGISEIDFICAAKTSALYEQGI
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: Y2240_SYNPW
Sequence: MYVIELALRMSPMPVSVQRKEHDSAEALYQQVRSALEQGQPRLLELCCEKVEGKRLSVLTSDLLAVQIYEKTAASGGTKRPGFSFEA
What are the official names of this protein?
UPF0367 protein SynWH7803_2240.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: AROC_MARMM
Sequence: MSHNTFGHLFRVTTWGESHGPSIGAVVDGCPAGIPLTETDLQPFLDLRRPGTSRHVTPRQEPDQVRILSGTFEDDRTDGPVTTGAPISLMIENTDQRSKDYSAIRDKWRPGHADYTYDMKYGIRDYRGGGRSSARETAMRVAAGGIARKVLGDGISIRAALVQVGDRAIDRSRWDWDEVSNNPFFCPDATTAALWEADMDALRRAGSSTGAIVEVVVSGVPVGWGAPVYAKLDSELAAAMMTINAVKGVEIGAGFGSAAMRGEDAADEMRMGEDGPVFLSNHNGGVLGGISTGQDLVVRFAVKPTSSITVERNTLDRNFEETVIETRGRHDPCVGIRAVPVGEAMAALVLADQKLRHAGQSAY
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PUR9_CERS5
Sequence: MTNLVPVGRALLSVSDKSGLLDLARALAELEVELISTGGTAATLRAAGLKVRDVAEVTGFPEMMDGRVKTLHPMVHGGLLALRDDDEHLVAMAAHGIEPIDLLVVNLYPFEAAVARGASYDDCIENIDIGGPAMIRAAAKNHRFVNVVTDTADYKALLDELRAHDGATTLAFRQKLALTAYSRTAAYDAAVSAWMAGALKSEAPRRRTFAGTLAQTMRYGENPHQKAAFYTDGSHRPGVATAKQWQGKELSYNNINDTDAAFELVAEFDPSEGPACVIVKHANPCGVARGATLAEAYGRAFDCDRVSAFGGIIALNQPLDAATAEKITEIFTEVVIAPGADEEARAIFAAKKNLRLLTTEALPDPLAPGLAFKQVAGGFLVQDRDAGHVDALDLKVVTKRAPSDAELADLLFAWTVAKHVKSNAIVYVKDGATVGVGAGQMSRVDSTRIAARKSQDMAQALGLAQPLTQGSVVASDAFFPFADGLLAAAEAGATAIIQPGGSMRDDEVIAAADEAGLAMVFTGQRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: MEP_PYRTR
Sequence: MRSFLLASLASLSVISVYGHPHARSTLTRRGVDLDSYRMKHAATYKNVAEVVADHNINTLAKRASAQDIATDLVKATIPNATFRLVSDSYVSDNGVAHFYFKQTANGLDIDTADFNVNIGRDGNVFSFGNSFYKGDVPAPPSLTKRDGSEPVAALKSAVDVLALPVSAQSATAEPKDATETYAIKKTTGTVSEPEARLVYLVDDEGKLALTWRVETDIMSNWLLSYVDVKDGSKVHAVVDYSADATYNVYPWGINDPTEGERQLVTDGFYPPASEFGWHNDGKMAFKTTRGNNGIAHTNWDNKMSGFLDLPRPTSEDLNFDYPFSLNQTDFHDYGNASITQLFYTSNKYHDLLYTLGFNEKAGNFEINNNGAGGVGQDFVYLNAQDGERFNNANFATPPDGSPARMRMYIWNQTTPFRDCSFEAGVVIHEYTHGLSNRLTGGPANSGCLSMLESGGMGEGWSDFFATAIRLKPSDTRAKDYTMGEWISGSEFGIRNYKYSTNLEVNPQVYTDVDQYTRVHPIGNIWASMLYEVLWNLIDKYGKNDDWLPEFNSAGVPKDGKYLAMKLALDGMALQPCNPTFVSARDAIIDADKALTGGANLCEIWSGFAKRGLGEKAVYSTGGRTNSFDVPAGVCNNSTVSSQARRVKLPLSV
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Extracellular metalloproteinase, Elastinolytic metalloproteinase MEP, Fungalysin MEP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHEB2_MYXXD
Sequence: MGKKVSVLVVDDSLICRQLICEALSKDPDIEVVGTCADGKQAVEMTKELRPHVITMDVDMPVMDGLTATEHIMAECPTPILVLTADPRSQAPELTYRALELGALALQIKPAIDAGPDAWNLVREIRLLSSVRVIRHLRRPQRGPLLPPRVATSVLPAVSMGVVVVAASTGGPQVLFKMLSELPADFPAPIVIVQHINAAFAESLAGWLAGASKLKVRLAQDGEPLMPGHVLIAPPGQHTVIPFRGRVGIKLGVERDGHMPSGTVLLESAARTYGRRAVGLVLTGMGADGADGLLAIKQAGGLAVAQNEESCVVFGMPGAAVERKAVDHLIHGDEVAATLVRLARGESLSVGR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENB_ECOLI
Sequence: MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQPDFSKFKRNP
What is the function of this protein?
Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA synthase, DHNA-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
Protein: QUEC_GLOVI
Sequence: MKKALVVFSGGQDSTTCAALACREYDEVHAVTFEYNQRHAIELESARAVGQALGLTGHEFIRLGPLLKGTSPLVSDAPLGQYASAAELPAGVEPTFVPGRNILFLTLAANRAFCLGTGDIVIGVCEADFAGYWDCRQVFVEAMARALGEGIYGDANAIRIHTPLMRLTKAETVKLSVEVLGERFEEVLALSHTCYAGVRGGCGRCHACILRDRGFREAGVPDPIWKFRKEPVSL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ISPG_ECO24
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.