PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_STRPD
Sequence: MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKEEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAAHKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_BACC1
Sequence: MDINLFDFHLPEELIAQVPLEERETSRLMVLDRETGDIEHKHFTDILSYLHEGDCLVLNETKVMPARLHGVKEDTGAHIEVLLLKQEEGDKWETLVKPAKRVKEGTVISFGEGKLKATCTGTADQGGRQLEFSYDGIFYEILDELGEMPLPPYIKETLEDRDRYQTVYAKEIGSAAAPTAGLHFTEELLEKLKQKGVELAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAALLNRVKENGGRIITVGTTSTRTLETIATDHDGKLCAASGWTDIFMYPGYEFKAIDGLITNFHLPKSTLIMLVSAFANRDNVLHAYNEAVKEKYRFFSFGDAMFVASHAKMGNK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL37_METST
Sequence: MKGTPSFGKRNKKNHIRCRRCGRNAYNPTKKYCASCGFGRSKRLRRYSWQNKKPVTGKRLK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.
Protein: DHAS_LEGPN
Sequence: MSRHLNVAIVGATGAVGETFLTVLEERNFPIKSLYPLASSRSVGKTVTFRDQELDVLDLAEFDFSKVDLALFSAGGAVSKEYAPKAVAAGCVVVDNTSCFRYEDDIPLVVPGSESSSNRDYTKRGIIANPNCSTIQMVVALKPIYDAVGISRINVATYQSVSGTGKKAISELVAQVGDLLNGRPANVQVYPQQIAFNALPHIDQFEDNGYTREEMKMVWETRKIMEDDSIMVNPTAVRVPVIYGHSEAVHLELKKPLTADDARALLAKAPGVTVVDNLSKASYPTAIKNAVGHDDVFVGRIRQDISHPCGLNLWIVADNIRKGAATNAVQIAEILQREFLLKLSLPQ
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: VTNC_HUMAN
Sequence: MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL
What is the function of this protein?
Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
What are the official names of this protein?
Vitronectin, VN, S-protein, Serum-spreading factor, V75.
What are the subcellular locations of this protein?
Secreted, extracellular space. SUBCELLULAR LOCATION: Parasitophorous vacuole. Note=(Microbial infection) In P.falciparum-infected red blood cells, VTN internalization is detected at the early trophozoite stage (PubMed:29567995). Colocalizes with SERA5 at the schizont stage and with SERA5 P47 at the merozoite surface (PubMed:29567995).
Protein: BPT_XYLFM
Sequence: MAIDSKPHDDLQLFKTNLHPCGYWPDRWASDLVMDPNDPRLGAIYPQTLAWGFRRSGNLLYRPHCEHCNACVPVRVNVNAFVPNRSQRRCLARNATLVTRIVPAERNAEQLSLYRRYLHQRHPDGGMDGHGAIEFDQFLIGPWGYGRFMEIREPATNGTPGQLLAVAVTDLIHQALSAVYTFYEPNAAARGLGTLAILHQIHWAQREQRPYLYLGYWIKDHFKMDYKRRFQKLEIYDGYCWRPFSTTYPTTHTL
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.
What are the official names of this protein?
Aspartate/glutamate leucyltransferase.
What is the protein family that this protein belongs to?
Belongs to the R-transferase family. Bpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_STRP8
Sequence: MKKRLFVLSLILLVALDQLSKFWIVSHIALGEVKPFIPGIVSLTYLQNNGAAFSILQDQQWFFVVITVLVIGYAIYYLATHPHLNIWKQLALLLIISGGIGNFIDRLRLAYVIDMIHLDFVDFAIFNVADSYLTVGVILLVICLWKEEDYGN
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MED3_KLULA
Sequence: MAVGPPDQIFKDNLTFDTFRELIIEKESTADEVADKVLEAKKALLPIRTLMTEFVGMIANLESMGNKTSQEKFLAIRMKLIELQNNIQKFSKDFQQLQPVMRTMDKFNEEVNAGEKKFFVQETLGYTQLASNGSAAGITKTSSGNDGNTTGSTANTMAMAKGLKKNAAGKPNTGTGVQSGPGRRNSTKKTGHTGPATAPTTSNSAASAAAAAANTPSLKQIPNTQPMQLMPGVSPMAMASPLNNISPQRKLTQHVNQSRENSLHQGVTPSASMITPQNILNMSAFDLNQNQTPQSLDNVNNMDLTNLDLDSLNMEFLN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 3, Mediator complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPPH_NITMU
Sequence: MIDRNGYRSNVGIILLNSKNEVFWGKRIRQDSWQFPQGGIKPGESPEQAMYRELTEEVGLRPWHVQILGRTRDWLRYDVPAQWIKRDWRGNYRGQKQIWYLLRLLGSDCDVSLHTSGRPEFDAWRWNQYWVELESVVEFKRQVYRQALTELARLLNRPPVPFGYSGYEKYDYSASGPLTGSTAKQSE
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: MTND_HUMAN
Sequence: MVQAWYMDDAPGDPRQPHRPDPGRPVGLEQLRRLGVLYWKLDADKYENDPELEKIRRERNYSWMDIITICKDKLPNYEEKIKMFYEEHLHLDDEIRYILDGSGYFDVRDKEDQWIRIFMEKGDMVTLPAGIYHRFTVDEKNYTKAMRLFVGEPVWTAYNRPADHFEARGQYVKFLAQTA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site (By similarity).  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway (PubMed:15938715).  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity).  Also down-regulates cell migration mediated by MMP14 (PubMed:14718544).  Necessary for hepatitis C virus replication in an otherwise non-permissive cell line (PubMed:11602742).
What are the official names of this protein?
Acireductone dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, MTCBP-1, Submergence-induced protein-like factor, Sip-L.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the plasma membrane when complexed to MMP14.
Protein: QUEF_VIBVY
Sequence: MSKYSDAKELAGLTLGKKTDYANQYDPSLLQPVPRSLNRDDLQLGDELPFMGHDIWTLYELSWLNNKGLPQVAVGEVYIPATSANLIESKSFKLYLNSYNQTRFDSWEEVRQRLITDLSHCAGEAVEVAVNSVTHYTQQPIVTMEGECIDEQDIDISSYDFDDRLLEGAAGEEWVTETLHSHLLKSNCLITNQPDWGSVEIRYQGHKIDREKLLRYLVSFREHNEFHEQCVERIFTDLMKYCQPESLTVFARYTRRGGLDINPYRSTEQAKPDHNHRMARQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_XANOP
Sequence: MIDTTRYPRLSRIHTPDDLRRFDEAELTVIAEELRSYLIESVGKSGGHFAAGLGVIELTVALHYLYQTPVDQLVWDVGHQTYPHKILTGRRDQIHTVKQKDGVAPFPKREESVYDTFGVGHSSTSISAALGMAIAAQRNGDDRKVVAVIGDGAMTAGMVYEALNHAGGMDPEPNLLVILNDNRMSISEAVGGLTKMLGRASGSRTLNAIREGGKKILGDKKNNPTARFVRRWEEHWKGMFVPSTLFEEMGFHYTGPIDGHDLPRLVGALKTLQTLKGPQLLHVITTKGKGYELAEGDQIGYHAVSPFDPSKGLVAKGGAKKPTYTDVFSDWVCDMAAAEPKLLVITPAMREGSGLVRFSKEYPQRYFDVAIAEQHAVTLAAGMATQGAKPVVAIYSTFLQRGYDQLVHDVAVQQLDVLFAIDRGGVVGPDGATHAGNLDLSFLRCVPHMVVMAPADEAECRQMLSTGMQYQGPAAVRYPRGTGPGAALDSSLATLPIGKAQLRHSGTRIALLGFGATVDAAEAVGRDLGLTVVNMRFVKPLDKAMLLELAKTHEGFVTIEDNVVAGGAGSGVSELLNAEAITLPMLHLGLPDSFQHHASREDLLAEAGIDQAGIRTAVLKRWPQLMTGKTPSLNAAAG
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: HUTI_BRUAB
Sequence: MTKNSSTVFTHARIATLEEKAANLGLIEEAALVVKDARIVYAGPENKLPDEYASFEKIDCGNRLITPGLIDCHTHLVHAGNRAHEFELRLQGATYEEVARAGGGIVSSVRNLRAASEDDLVRETLPRLDALIAEGVTTVEVKSGYGLDRDSEIKSLKAARRLGEERDVAIRTTFLGAHALPPEMNGDKAAYIDRVINDMLPAIAEQGLADAVDGFCEGIAFLPDEIARVFDAAKAHDIPVKLHADQLSNLHGAALAASYGALSADHLEYTDADGAAAMASAGTVAVLLPGAYYFIRETQKPPVEAFRAAGTKMALATDNNPGTSPLTSLLLTMNMGATLFRMTVEECIAGVTREAARALGILDQTGTLEIGKDADLAIWDIERPAELVYRIGFNPLWKRVFKGQI
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_VIBVY
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVMVGGEITTSAWVDIEELTRETVREIGYVHSDMGFDANSCAVLNTIGKQSPDINQGVDKADPKEQGAGDQGIMFGYACNETEVLMPAPITYAHRLMERQAKVRKDGTLPWLRPDAKSQVTFQYEQGKIVGIDAVVLSTQHCDSISTPDLREAVMEEIIKPVLPSEWLNKETKYFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSYAIGVADPTSIMVETFGTEKVSHDIIIEAVRQFFDLRPYGLQEMLNLLQPIYKKTAAYGHFGREEFPWEATDKAALLREFAGIK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRVA_AMPME
Sequence: SMTDVIPEADINKAIHAFKAGEAFDFKKFVHLLGLNKRSPADVTKAFHILDKDRSGYIEEEELQLILKGFSKEGRELTDKETKDLLIKGDKDGDGKIGVDEFTSLVAES
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin alpha.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: MUB1_SCHPO
Sequence: MRESNVSIVWNNKASVTINTVLYDRRALDCDSEMSLMNSLSHLVYLTSTSPKIREILTMDGGLMRLMNILRAGRGQTFARMTIWQLALQCVVNVGIRGSEAIRIRVVEAGIVPIVVTLLDDFLFALESVVSHHSRFQFSLTPSTTPPPSSASAPFPINSNISNSLDSVSQHNSSADSLFVNGDVPSPFGASTASSSSRRVYSVDLRDSGDVQLPNQSTFRHSVNRDLLGSSSTTSHDRSSGSIYSNDSFQDPRVQANSPLTIQRISSAAPSTPTSTENVNYNMTTPSSPSYSRQTGPASETINDEIDSPNFFFPTPLNIMTTTQDSSRDVQLSLNNVQSQALNNRQRRNQLLPGVPSTSALLDGRRPENVVDYHGIASFFDNFDKKINKLPREEDILFGLQILAYTSKNYFHMRPYFESSKDVPSLRMSPLRSGSKTWNIFQLVEQFTLKFYPPQVQYWARAIMNNYCRKDESHGGIRRCANLLCNKWEEHSRQFAKCRRCRRTKYCSKECQHQAWPGHSRWCRVIHKDGRNSKRESSKINSVTESESTASPAASVIPVGTESVTSSTQSDSRL
What are the official names of this protein?
MYND-type zinc finger protein C31F10.10c.
What is the protein family that this protein belongs to?
Belongs to the MUB1/samB family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: WNT8_XENLA
Sequence: MQNTTLFILATLLIFCPFFTASAWSVNNFLMTGPKAYLTYSASVAVGAQNGIEECKYQFAWERWNCPESTLQLATHNGLRSATRETSFVHAISSAGVMYTLTRNCSMGDFDNCGCDDSRNGRIGGRGWVWGGCSDNAEFGERISKLFVDGLETGQDARALMNLHNNEAGRLAVKETMKRTCKCHGISGSCSIQTCWLQLAEFRDIGNHLKIKHDQALKLEMDKRKMRSGNSADNRGAIADAFSSVAGSELIFLEDSPDYCLKNISLGLQGTEGRECLQSGKNLSQWERRSCKRLCTDCGLRVEEKKTEIISSCNCKFHWCCTVKCEQCKQVVIKHFCARRERDSNMLNTKRKNRGHRR
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Plays a role in ventral mesodermal patterning during embryogenesis.  Mimics Nieuwkoop center activity.  Causes dorsal mesodermal differentiation of animal cap ectoderm when coexpressed with noggin and nuclear, sequence-specific DNA-binding protein xBra.  None of these molecules causes dorsal mesoderm formation when expressed alone.
What are the official names of this protein?
Protein Wnt-8, XWnt-8.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: Y5373_DELAS
Sequence: MPFDPRTTPLTAVEARVLATLMEKARTVPDSYPLTLNALVTGCNQKSSRDPVMEVSEGEAQEALDSLRLRTMSVQISSARATRWEHNFPRGVGVPDQSAVLLSLLMLRGPQTAGELRINSERWHRFADISSVEAFLEELRERSEEKGGPLVVLLPRAPGAREQRWAHLLCGPVDVNAMAQPPAAAGARGDALAQRVVDLEAQVQQLQARLAHVYAQLGLEEPGQSS
What are the official names of this protein?
UPF0502 protein Daci_5373.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: IGDC4_MOUSE
Sequence: MARADTGRGLLVLTFCLLSARGELPLPQETTVKLSCDEGPLQVILGPEQAVVLDCTLGATAAGPPTRVTWSKDGDTVLEHENLHLLPNGSLWLSSPLEQEDSDDEEALRIWKVTEGSYSCLAHSPLGVVASQVAVVKLATLEDFSLHPESQIVEENGTARFECHTKGLPAPIITWEKDQVTVPEESRLITLPNGVLQILDVQDSDAGSYRCVATNSARQRFSQEASLTVALRGSLEATRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPISTDVIVLGRTNLLIASAQPRHSGVYVCRANKPRTRDFATAAAELRVLAAPAISQAPEALSRTRASTARFVCRASGEPRPALHWLHDGIPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGTACAAAPLAVVVREGLPSAPTRVTATPLSSSSVLVAWERPELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQLGASRTSSPALVHTLDDVPSAAPQLTLSSPNPSDIRVAWLPLPSSLSNGQVLKYKIEYGLGKEDQVFSTEVPGNETQLTLNSLQPNKVYRVRISAGTGAGYGVPSQWMQHRTPGVHNQSHVPFAPAELKVRAKMESLVVSWQPPPHPTQISGYKLYWREVGTEEEADGDRPPGGRGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPTPDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLVTYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWCPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLESDTRYFFKMGARTEVGPGPFSRLQDVITLQKTFSDSLDVHAVTGIIVGVCLGLLCLLACMCAGLRRSSHREALPGLSSSGTPGNPALYTRARLGPPSVPAAHELESLVHPRPQDWSPPPSDVEDKAEVHSLMGGSVSDCRGHSKRKISWAQAGGPNWAGSWAGCELPQGSGPRPALTRALLPPAGTGQTLLLQALVYDAIKSNGRKKPSPACRNQVEAEVIVHSDFGASKGCPDLHLQDLEPEEPLTAETLPSTSGAVDLSQGADWLGRELGGCQPTTSGPERLTCLPEAASASCSCSDLQPSTAIEEAPGKSCQPKALCPLTVSPSLPRAPVSSAQVP
What are the official names of this protein?
Immunoglobulin superfamily DCC subclass member 4, Neighbor of punc e11, Protein DDM36.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. DCC family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: UVRC_KORVE
Sequence: MDLHQKIRTLPTSPGVYLYKNAEGEIIYVGKAKNLRSRVGSYFVRGADENSKTGSLLREAVDVEYIVVDNEKEALALENNLIKQKKPRFNILLRDDKTYPYIKLTMGEKWPRVYVTRRLKKDGSEYYGPFFPANLAYRVVDLIHRNFLVPSCYIDLRRYHPRPCLQHYIGRCLGPCVEGLTNEVQYGEAVKDVKLFLEGRHSDLKQSLTARMNKAAEGMQFELAAKYRDLITTVEDLHQKQRIAAAEGDDADVFGYHYENHMVAVNLFHMRGGKVLDRRDFFFEDLGEMEATGGLNTGEFFSTLLQQIYLDNKYVPRTIYVPVEFEDREALCEILSEQMHRKIDINVPQRGDKRSLIDLVAQNAKQSYDQRFRVMRPQTDVLKSVLQDTLELPELPNRIECFDISHIQGAETVASMVVWEDGKMKKSDYRKFIIKTVQGVDDFASMREVVTRRYKRIVEENQPMPSLVLIDGGVGQLHAAAGALEAIGITNQPLASIAKREEIIYVHGREDEPIRIDHHSPVLHIIQLIRDEAHRFAITFHRKRREIRDRSNELLEIPGIGEQAMKRLLRHFGSIQSIRTANATSLEAVVNRTQAEAILAHFRAEETTRS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLG7_SCHPO
Sequence: MGLGFSSKKQLPAYCGPLPVGSLVLELSVPEEFRCEYKTIEHKLRTVKVRIFYPLDPTKDVEPRTDELWLPFHEGIPEVAKGFRWWLLRAFASGLTNLALPVYKGELFHPPNNGKLPVFIFSHGLVGSRNVYSSLCGTIASYGIVVLAMEHRDNSAIISTVRDPLHPEEPPYVVQYREISDFYADATVVLQNERLLFRQQEIQIALQMIRNINDLGTPDENLPFLCSVDSSFYNSVFQSMKGNLNTAQGELIVAGHSFGAATCAFISGSSTKSLYNDYMFHTEFKCSILYDIWMLPVRQLHLSTMRYPTLMIISYEFRRFVDNFQALESWLVNKDSENQNAGESADEKMSVVPLKKYSHVFVYDGTVHANQSDLPILLPRMVLRVLKGKFEADPYEALRINTRSSVQFLRENHVENVQGDNDPSSLQTNIIPGWERIM
What are the official names of this protein?
Putative phospholipase A2, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase.
What is the protein family that this protein belongs to?
Belongs to the serine esterase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GYRA_MYCLE
Sequence: MTDITLPPGDGSIQRVEPVDIQQEMQRSYIDYAMSVIVGRALPEVRDGLKPVHRRVLYAMLDSGFRPDRSHAKSARSVAETMGNYHPHGDASIYDTLVRMAQPWSLRYPLVDGQGNFGSPGNDPPAAMRYCVSGNSLVRLLFGKSIRIGDIVTGAQFNSDNPIDLKVLDRHGNPVVADYLFHSGEHQTYTVRTTEGYEITGTSNHPLLCLVNVGGIPTLLWKLIGEIRSGDYVVLQRIPPVEFGPADWYSTMEALLFGAFISGGFVFQDHAGFNSLDRDYFTMVVNAYDTVVGGLRCISSRITVSGSTLLELDVYNLIEFKKTRLSGLCGQRSADKLVPDWLWHSPSTVKRAFLQALFEGEGFSSILSRNIIEISYSTLSERLAADVQQMLLEFGVVSERYCHTVNEYKVVIANRAQVEMFFTQVGFGVTKQAKLIRDVVSMSPCVGMDINCVPGLATFIRKHCDNRWVEEDSFNQHNVDCVQHWHHHSAEIVGHIADPDIRAIVTDLTDGRFYYARVASVTDTGIQPVFSLHVDTEDHSFLTNGFISHNTEARLTPLAMEMLREIDEETVDFISNYDGRVQEPMVLPSRFPNLLANGSGGIAVGMATNIPPHNLYELADAVFWCLENHDADEETMLVAVMERVKGPDFPTAGLIVGSQGIADAYKTGRGSIRIRGVVEVEEDSRGRTSLVITELPYQVNHDNFITSIAEQVRTGRLAGISNVEDQGSDRVGVRIVIEIKRDAVAKVVLNNLYKHTQLQTSFGANMLSIVDGVPRTLRLDQMICYYVEHQLDVIVRRTTYRLRKANERAHILRGLVKALDALDEVITLIRASQTVDIARVGVVELLDIDDIQAQAILDMQLRRLAALERQRIIDDLAKIEVEIADLGDILAKPERRRGIIRNELTEIAEKYGDDRRTRIIAVDGDVNDEDLIAREEVVVTITETGYAKRTKTDLYRSQKRGGKGVQGAGLKQDDIVRHFFVCSTHDWILFFTTQGRVYRAKAYELPEASRTARGQHVANLLAFQPEERIAQVIQIRSYEDAPYLVLATRAGLVKKSKLTDFDSNRSGGIVAINLRDNDELVGAVLCAADGDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNADDRLLSLNVVREDTYLLVATSGGYAKRTSIEEYPMQGRGGKGVLTVMYDRRRGSLVGAIVVDEDSELYAITSGGGVIRTTARQVRQAGRQTKGVRLMNLGEGDTLLAIARNAEESADGVSVKVMISRSRVLSFFGSDSNTSPDRT
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state (PubMed:17325221).  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WETA_METRA
Sequence: MAFWTVPYRAEAVDTNRDPSMYWEDINSASTDDAHNDFFGQFVDFDADGTVTATTDNDFNTVPASMPGVPESMLLMGDRTVATLESAVSSCVSSADEFDFLSSSSRIGPTASAASHEIDPKDLTLSADELAHPSQQQFDYLGRGSMSEADLSRLESISLHSPQRPQNTTSSDTPSPKPPNTDARKPKKFVEALSSTIRKATNLRRNRKAAAVPRQVSPPQEHLQPLKIPKQRRGRGRAVTQGNLPVSPPLQQQEQATPHFIHGQCDDPFNDTALLPPGGVNLQYYGQVAPDTPVESPGVKNEPNQSHFQVDMAWQHHHHPHHHHQQQQHPPPPPHPHPHPHHHQQQQQQHQHQHQHHHQQQQHHQQQQQQQHQMHWTGTGGEYITSQEAGWWTPNMMSQGPNDFSHHQRSASVHVMGHGQHTGMPYDYGAIADTSTGGLMIHMPQPRGSQSSVVNDLTVNAQTFLPPPPPIPQAIGQKMPGSERSHRPPKAKSSGARHLSCSPVRKQRGPSSSPTPADQSAVPRSRHSSGASVSSLRSSSGRLPASMPGTPCSVRKRRSRDISGSNSATSLGGSDGASGIGFVNFTPNDGSVLMTGVAPSGSSKTKARREKEAQDRRRRLSEAAIKAVAAAGGDVDKLIEQGFAF
What is the function of this protein?
BrlA, abaA and wetA are pivotal regulators of conidiophore development and conidium maturation.  They act individually and together to regulate their own expression and that of numerous other sporulation-specific genes (PubMed:28447400).  BrlA, abaA and wetA act together to positively regulate the expression of the Pks1 gene cluster that mediates the biosynthesis of an anthraquinone derivative pigment that contributes to conidial pigmentation that provides protection from UV radiation, heat and cold stress (PubMed:28447400).
What are the official names of this protein?
Developmental regulatory protein wetA.
What is the protein family that this protein belongs to?
Belongs to the wetA family.
Protein: HEM6_SALPB
Sequence: MKPDAHHVKQFLLRLQDDICQTLSAVDGANFVEDSWRREAGGGGRSRVLRNGGIFEQAGVNFSHVHGDAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYIPTSHANVRFFIAEKPGADPVWWFGGGFDLTPYYGFEEDAVHWHRTARDLCQPFGDDVYPRYKKWCDDYFFLKHRNEQRGIGGLFFDDLNTPDFDHCFDFMQAVGNGYTRAYLPIVERRKAMVWGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDWQPEAGSPEAALSEFIQVRDWI
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.