PharMolix/UniProtQA huggingface dataset:
Protein: RTC5_ARTBC
Sequence: MGAGQSTNTSGHGASPEEMSRILAHRFASKCFTPLELTHLKDNFYSLALKQGDIHYWNEEVLSRFLGIPDGDEKFGLGTLDAGPVIFRMVSYLGAFPFQNTLAPSVLTFDAMVKVIVLLTDRYGKVLRRGKKDRIKLLFGSLADIGRKEASPITSGDKSDNDQGRPKTRSDEAGFSVDKPSNDADDYNDDDDLVLAALESLDAIEVFKHDQRIDRTAYEAHISFDTFQRLLMLFVVIAPLQSCEKTSEYFSQLNEESLKSARYCVENILTSFDIGDRTKGIDYETFYWVISTSLPYMFDPLTPLFEHLLFSKNLDLSRRKDSGTCSVSEEKQKKTEFCISPSHPPIILPGSFKPCILDSAVISHLSFFLSTSFPTPNLLQNGTRLHGVFSSDTHGESLTSFSHNVLTWDAPSILLVTGSINHSSGDEADIITVGAYIPQPWKLPASTSTSHYDTSHQSQLPYLFQLSPRYAVMQGSPSINSLKPNLPVVSFSTKSGIAIGCKIPPPTRTSMDSSRPTPAGSGSLWIDPALENAEFVMSNGLSHEEGVFLPPGIARWSPSRPPSKAESETIKISIYNIEVWGVVQTAPTPAQSPYHSRTSTANGDIPDAVARQQANWNFEAREAERRREIHLNVGGGDSEEQTGRALLEMAGIIGDSARRR
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_CLOBH
Sequence: MPKVDLFNQNGEKVGDLQLADSVFGVEVNTYAMHQVVKALLANKRQGTQSAKTRAEVSGGGIKPWRQKGTGRARQGSIRAPQWIHGGVVFAPKPRDYRMSIPKSMKKVAIKSALTSKVNENLMVVVDEIKLETPKTKEVVKMLNSFNAKKTLIITNNAEENVYKSARNIEGVQIIPVNNINVYDVLKYDKVVITKDAVSKIEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: FMT_RHOPS
Sequence: MPLRLVFMGTPDFAVPTLLALSAYGHDIAAVYSREPKPAGRGMKLQHSPVAQEAQRFGIPVLTPKTLKTDEALAEFRSHDADAAVVVAYGMILPQAILDAPRLGCYNLHGSLLPRWRGAAPLNRAIMAGDAESGVMVMKMDAGLDTGDVAMAERIAITDAMTVTDLHDSLARLGADLMVRAMAALERDQLQLTRQSEHGVTYAAKIDKAEAKIDFARPAQAVLRHIHGLSPFPGAWCELPIDGEAVRVKILRCASATGGGAPGQVLDDRLTIACQDGAIRVLQLQRAGKQPMQADEFLRGTPIAAGAVIV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Z385D_RAT
Sequence: MRKIMYFGGTCQSPALPALIHPPAPPLQPSLDIKPFLPFPLDTAATVNLFPNFNAMDPIQKAVINHTFGFPLPHRKKQIISCNICQLRFNSDSQAAAHYKGTKHAKKLKALESMKNKQKSVTAKDSAKTTFTSITTNPITTSSDKTESTAGTQVIARSADMRKSSEVTTELTSNAEKSLTAAVAAGNNSSPPTETEEEKAKRLLYCSLCKVAVNSASQLEAHNSGTKHKTMLEARNGSGTIKAFPRAGMKGKGPVNKGNTGLQNKTFHCEICDVHVNSETQLKQHISSRRHKDRASGKPPKPKYSPYNKLQKAAHPLGVKLVFSKEPSKPLTPRILPNPLAAAAAAAAVAVNSPFSLRTAPAATLFQTSALPPALLRPAPGPIRTTHTPVLFSPY
What are the official names of this protein?
Zinc finger protein 385D, Zinc finger protein 659.
What are the subcellular locations of this protein?
Nucleus.
Protein: FBD8_ARATH
Sequence: MYPKAKATRVCSDAARINDLPDDLLATVLSFVPTKDAVATSILSKRWRPIWKRAVNLESDCVELCAICALDCFSFILMRSSKLRVLRFKQKRCCCNLLREKWKQPDFVPLSLYRSLEAFEWIGFKGREKTEKKAAFHILRNACNLKTMAITTSNTFQENTNILIDFDRMCTNCRISIKP
What are the official names of this protein?
Putative FBD-associated F-box protein At3g12840.
Protein: DPOL_HBVF2
Sequence: MPLSYPHFRKLLLLDDEAGLLEEELPRLADEGLNRRVAEDLNLQLPNVSIPWTHKVGNFTGLYSSTVPTFNPDWLTPSFPDIHLHQDLIHKCEQFVGPLTKNELRRLKLVMPSRFFPKVTKYFPMEKGIKPYYPDNVVNHYFKTRHYLHTLWKAGILYKRESTRSASFCGSPYSWEQELQHGSTSINDTKGHGTESLCTQSSGILSRPSAGSSIQGKFQQSRLGLQQKQGQLANGKQGRSGRIRSWVHTPTRWPAGVEPTGTGCAYNIASRSASCFHQSAVREKTNPSLSTSKRHSSTGHAVELNPVPPGSVRSEGKGSVLSCWWLQFRDTEPCSDYCLSHIINLLEDWGPCYEHGQHHIRTPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGNTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSTSRIHDHQHGTMQNLHNSCSRNLYVSLLLLFKTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDLVLGAKSVQHLESLYTAVTNFLLSVGIHLNTSKTKRWGYTLNFMGYVIGSWGSLPQDHIVQKIKACFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACITAKQAFVFSPTYKAFLCQQYMHLYPVARQRPGLCQVFADATPTGWGLAIGHQRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLRLPFQPTTGRTSLYAASPSVPSHLPDRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: YHAM_LISMC
Sequence: MEKRLLDFEVGETVDLFLLIKSSVKGTASNGKPFLSLVLQDKSGELEAKLWDVKESDEANYGVQQIVHLMGDIQNYRGRKQLKIRQIRQATALDGVSASEFMETAPINKEEMADEITQYIFEMKNANLQRITRALLKKYQDDFYDYPAAMRHHHEFVSGLSFHVVSMLRLAKSVADLYPSVNRDLLYAGVILHDLGKVIELSGPVSTTYTLEGNLIGHISIVVEEVSKIADELSIDGEEVVVLKHVLLSHHGKGEWGSPKPPLVREAEILHQIDLMDASLNMMDKVLKHTKPGEFSERVFGLDNRSFYNPIFE
What is the function of this protein?
Shows a 3'-5' exoribonuclease activity.
What are the official names of this protein?
3'-5' exoribonuclease YhaM.
What is the protein family that this protein belongs to?
Belongs to the YhaM family.
Protein: GPMA_CUPPJ
Sequence: MYKLVLIRHGESTWNLENRFTGWVDVDLTDTGAAQARLAGKLLKEAGFAFDVAYTSVLKRAIRTLWHVQDEMDEMWIPVRNEWRLNERHYGALAGLNKAETAAKFGDEQVLVWRRSYDTPPPALEPTDPRASYDDPRYANVPREQIPLTECLKDTVARVLPLWNESIAPDIQSGKRVVIAAHGNSIRALVKYLDQISDDDIVGLNIPNGTPLVYELDASLRPLRHYYLGDQEAIAASLAAVASQGKAR
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: ISPD_THET8
Sequence: MEVSVLIPAAGNGLRLGRGPKAFLQVGGRTLLEWTLAAFRDAAEVLVALPPGAEPPKGLGAVFLEGGATRQASVARLLEAASLPLVLVHDVARPFVSRGLVARVLEAAQRSGAAVPVLPVPDTLMAPEGEAYGRVVPREAFRLVQTPQGFFTALLREAHAYARRKGLEASDDAQLVQALGYPVALVEGEATAFKITHPQDLVLAEALARVWSA
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: FB26_ARATH
Sequence: MNRGANSASIPNDLILEILSRLPAKSTGRFRCVSKLWGSMLCHSYFTELFLTRSSARPRLLIGIHQDGDRFFFSCPQPQSPYDNSSIVLAADFHMKFGRVEDEWVYHILTLGTENVRWREIICPFSYDPPREKPICINGVLYYISVGSYYSLIGCFDVRSEKFKFLYLSPDCFPNWSRKLINYKGKLGVTIMEDYHGGFPLKLRMWVLEDVEKEEWTRYAYTLRPENKVEDNDYVYVVGATASGEIVLTKQNAYKPFYVFYFSPERNTLLSVEIQGVGEEWFYHNVYYFVDHVEDLRFDVMKTTYAGTSRSPPKQSTSTSSREDHEVRTLAHQKEDRLTFESVNQFDALRLLEDD
What are the official names of this protein?
F-box protein At1g31080.
Protein: TUSD_SALPB
Sequence: MRYAIMVTGPAYGTQQASSALQFAHALLNEGHELASVFFYREGVYNANLLTSPASDEYDLVRAWQKLNTQHGVALNICVAAALRRGIIDETEAGRLALPSANLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_BRUA2
Sequence: MTDLRHYDVIVSPVITEKSTIVSEHNQVVFNVARKATKPEIKAAVEALFGVKVTAVNTAVRKGKVKRFRGLVGRQSDVKKAIVTLAEGQSIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL23_RHIE6
Sequence: MTDLRHYDVIVSPAITEKSTLVSENNQVVFNVAKQATKPEIKAAVEALFGVKVTAVNTLLRKGKTKRFRGFVGKQKDVKKAVVTLAEGQTIDVSTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: DUT_MARMM
Sequence: MSTVPVKIKPLDHYEGLALPAYETPQSAGMDLRAAVPADEPVSIPPGEWRLIPVGIAIALPAGFEAQVRPRSGLAAKHGISCVNTPGTVDADYRGEIRVNLINHGQANFVVNRGDRIAQMIIAPVTQAVWEIADTLDETTRGTGGFGSTGTK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: EX7L_CAMJE
Sequence: MTPTELNLKAKALLETHFDDIVLSGEISKITLHGSGHWYFDLKDERSSIACAMFKGANLKVGFKPAVGDFLELCGSVSLYPESGRYQFIATSMKKAGFGDLEAQFLALKERLQKEGLFDPRFKKSLPKFPKKVGIITSKTSAALQDMLKLIHQKEYFLAKIYIFDALTQGNNAPFSLIQALKKADDMDLDVLIIARGGGSREDLFCFNDENLAREIFKAKTPIISAIGHEIDYVISDFVADFRAPTPSAAIDTLFYSKLDIEQSLDLMEEKLMQLWNYKIQNYENLLLNLSKFFKFNSLPKIIDEKIKQSHNIEKQLNHLLANQMRYNELKLDKLQNAYLQHENFFNKSKKFICIRKNGKIANLEDLKSDDIVILSSQTSQKEAKIL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_STRP7
Sequence: MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVGGENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: KAIB_THEVB
Sequence: MAPLRKTYVLKLYVAGNTPNSVRALKTLNNILEKEFKGVYALKVIDVLKNPQLAEEDKILATPTLAKVLPPPVRRIIGDLSNREKVLIGLDLLYEEIGDQAEDDLGLE
What is the function of this protein?
A metamorphic protein which reversibly switches between an inactive tetrameric fold and a rare, thioredoxin-like monomeric fold (KaiB(fs)).  KaiB(fs) binds phospho-KaiC, KaiA and CikA.  KaiA and CikA compete for binding to KaiB(fs), and KaiB(fs) and SasA compete for binding to KaiC, thus the clock oscillator and output signal pathway are tightly coupled.
What are the official names of this protein?
Circadian clock oscillator protein KaiB.
What is the protein family that this protein belongs to?
Belongs to the KaiB family.
Protein: ANO10_HUMAN
Sequence: MKVTLSALDTSESSFTPLVVIELAQDVKEETKEWLKNRIIAKKKDGGAQLLFRPLLNKYEQETLENQNLYLVGASKIRMLLGAEAVGLVKECNDNTMRAFTYRTRQNFKGFDDNNDDFLTMAECQFIIKHELENLRAKDEKMIPGYPQAKLYPGKSLLRRLLTSGIVIQVFPLHDSEALKKLEDTWYTRFALKYQPIDSIRGYFGETIALYFGFLEYFTFALIPMAVIGLPYYLFVWEDYDKYVIFASFNLIWSTVILELWKRGCANMTYRWGTLLMKRKFEEPRPGFHGVLGINSITGKEEPLYPSYKRQLRIYLVSLPFVCLCLYFSLYVMMIYFDMEVWALGLHENSGSEWTSVLLYVPSIIYAIVIEIMNRLYRYAAEFLTSWENHRLESAYQNHLILKVLVFNFLNCFASLFYIAFVLKDMKLLRQSLATLLITSQILNQIMESFLPYWLQRKHGVRVKRKVQALKADIDATLYEQVILEKEMGTYLGTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSANIGVWQLAFETMSVISVVTNCALIGMSPQVNAVFPESKADLILIVVAVEHALLALKFILAFAIPDKPRHIQMKLARLEFESLEALKQQQMKLVTENLKEEPMESGKEKAT
What is the function of this protein?
Does not exhibit calcium-activated chloride channel (CaCC) activity.  Can inhibit the activity of ANO1.
What are the official names of this protein?
Anoctamin-10, Transmembrane protein 16K.
What is the protein family that this protein belongs to?
Belongs to the anoctamin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Shows predominantly an intracellular localization with a weak expression in the cell membrane.
Protein: SYA_YERPS
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVSSSSLVPNNDPTLLFTNAGMNQFKDVFLGLDKRAYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAINFAWELLTSEQWFNLPKEKLWVTVYETDDEAYNIWANEVGVPHERIIRIGDNKGGAFASDNFWQMGDTGPCGPCSEIFFDHGDHIWGGPPGSAEEDGDRYIEIWNIVFMQFNRQSDGTMLPLPKPSVDTGMGLERIAAVLQHVNSNYEIDLFRDLIAAVADVTGATDLSSKSLRVIADHIRSCAFLISDGVIPSNENRGYVLRRIIRRAIRHGNMLGAKETFFYKLVAPLIAVMGPAAAELKQQQAMVEQVLKTEEEQFARTLERGLALLDDELSKLTGDTLDGETAFRLYDTYGFPVDLTADVCRERNLKVDEAGFEQAMEAQRRRARESSGFGADYNSLIRVDSASQFSGYDHVQQHATVTALFRNGEAVDEIHAGEEAVVVLNRTPFYGESGGQVGDKGELKNATATFSVTDTQKYGQAIGHVGILTTGTLRVNHSVEALVDVVRRNRIRLNHSATHLLHAALRNVLGEHVAQKGSLVNDKYLRFDFSHFEAMKPEQIRLVEDLVNEQIRRNMPVQTEVMELDAAKEKGAMALFGEKYDDQVRVLTMGDFSTELCGGTHASRTGDIGLFRILTESGTAAGIRRIEAVTGEGAIALLHQQSDLLQDVAHLVKGDIHNLADKVRAVLDRSKMLERELQQLKDQQAAQESASLSSSAKLINGVKLLVSQLDNVEPKMLRTMVDDLKNQLGSAIIVLATTADDKVSLIVGVTKDLTGKVKAGELIADIAQQVGGKGGGRPDMAQAGGTDVQALPAALASVEAWVASRM
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBR1_XENTR
Sequence: MKIAVEGCCHGELDKIYETIQFLEKKENTKVDLLLCCGDFQAVRNEGDMKCMAVPQKYRQMQTFYKYYSGEKLAPILTIFIGGNHEASNYLQELPYGGWVAPNIYYVGYAGVVKYRGVRIGGISGIFKSHDYRKGHFERPPYSKDTVRSAYHVRNIEVFRLKQLKEPMDIFMSHDWPRSIYHYGNKKQLLKKKDFFRQEVENNTLGSPAASELLLHIQPSYWFSAHLHVKFAAFMQHQTNVEGEIPKATKFLALDKCLPHREFLQIVDVEHDPGKPDCLEYDLEWLAVLKATKDLLNITSKTWNMPENNGLHSRWDFSASEKTKREILDDLGHDIKIPCNFCMTTACYDPNNPQYKRVATHIVNPQTTEFCARLGLVDLNAKIRQHEEEGDIDITEDNEADSIGSAEDPGEYSTDTSLLSTSINPDEIALEDDDDQEDEGMAEKLGEPSPDYTPDLSINFSNIRVLPDSMAVSSDDATDSTNDELDRSESSQTEGEGKQSNRPLKRMSNENGSGGVKIKRRNQAIYQAKDDEDE
What is the function of this protein?
Cleaves the 2'-5' phosphodiester linkage at the branch point of excised lariat intron RNA and converts them into linear molecules that can be subsequently degraded, thereby facilitating ribonucleotide turnover.  Linked to its role in pre-mRNA processing mechanism, may also participate in retrovirus replication and have an antiviral cell-intrinsic defense function.
What are the official names of this protein?
Lariat debranching enzyme.
What is the protein family that this protein belongs to?
Belongs to the lariat debranching enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MGSA_SALCH
Sequence: MELTTRTLPTRKHIALVAHDHCKQMLMNWVERHQPLLEKHVLYATGTTGNLIQRATGMDVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVSTADFIIQSPHFNDAVDILIPDYARYLAERLK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: VIRB8_RHIRD
Sequence: MLVARESLAEHYKEVEAFQTARAKSARRLSKIIAAVAAIAILGNVAQAFAIATMVPLSRLVPVYLWIRADGTVDSEVSISRLPATQEEAVVNASLWEYVRLRESYDADTAQYAYDLVSNFSAPTVRQDYQQFFNYPNPSSPQVILGKRGRVEVEHIASNDVTPSTQQIRYKRTLVVDGKMPVVSTWTATVRYEKVTSLPGRLRLTNPAGLVVTSYQTSEDTVSNVGQGAP
What is the function of this protein?
VirB proteins are suggested to act at the bacterial surface and there play an important role in directing T-DNA transfer to plant cells.
What are the official names of this protein?
Protein virB8.
What is the protein family that this protein belongs to?
Belongs to the virB8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HSLU_PSEA8
Sequence: MSMTPREIVHELNRHIIGQDDAKRAVAIALRNRWRRMQLPAELRAEVTPKNILMIGPTGVGKTEIARRLARLANAPFIKVEATKFTEVGYVGRDVESIIRDLADAAVKMLREQEIQKVKYRAEDAAEERILDALLPAARPAMGFGDEPAREDSNTRQLFRKRLREGQLDDKEIDIEVADNPAGVEIMAPPGMEEMTNQLQNLFSGMSKGKKKTRKLKVAEALKLIRDEEAVRLVNEEELKARALEAVEQHGIVFIDEIDKIAKRANAGGADVSREGVQRDLLPLIEGCTVNTKLGMVKTDHILFIASGAFHLSKPSDLVPELQGRLPIRVELKALSPNDFERILTEPHASLTEQYRELLKTEGLAIEFAEDGIKRLAEIAWQVNEKTENIGARRLHTLLERLLEEVSFSAADLASEHSDKPILIDAGYVNSHLGELAEDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP4_ROTHL
Sequence: MEKLTDLNYTLSVITLMNNTLHTILEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKIAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIHDKLMVQSTGEIDMTKEINQKNVKTLGEWESGRNPYEPKEVTAAM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: 075R_IIV3
Sequence: MRETAKLILNSAFGKMIQKVIEDETNLISNAYSLRTFRDKFDSGYDLFQVSSHIDLIKGRLGKVDYSTSKPQHIGLFILDYTKKKMYDEIFSQTKVYYSDTDSALIEKSELLRLQQQGILKIGTDLGEYDVEMDDIGWLKVSTINTEDLNQPKAHDHL
What are the official names of this protein?
Uncharacterized protein 075R.
Protein: RL5_CHLSY
Sequence: MTVRLREKYQKEVVPALMEEFKFKSIMQVPRLVKIVVNVGVGEAVQNAKAIEAAVNDLATITGQKPVVTRAKKSVASFKLRAGMPIGAMVTLRGDRMYDFLDRLCSLALPRIRDFRGVSRSSFDGRGNYSLGLREQIVFPDIDYDKIDKIRGLEVAIVTSAPNDEQAYALLKRLGMPFRD
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL25_RICAE
Sequence: MSEILELEAESRTEFGTGAARALRRAGRVPAIIYGAGKTPVSISLEEKEITKYYRKPAFISQLINLTIDKKKYKVLPKAVELHPVTDIVRHVDFVFLEEKTQKMEVPVVYEGKERALGVKRGGYFNIVKRRVTLLCDVNNIPRNITIDVTNMPMATSLKSSKIELPKGCSFVTKKEFVLATIIGRRGAKTEAEGEQQAAEAGK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: AROB_ECOL5
Sequence: MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKPQVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_LYSSC
Sequence: MPTINQLVRKPRQSKITKSKSPALNKGYNSFKKSLTDVKSPQKRGVCTRVGTMTPRKPNSALRKYARVRLTNQIEVTAYIPGEGHNLQEHSVVLIRGGRVKDLAGVRYHIVRGALDTAGVNGRLQSRSKYGTKRPKEKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: GSA_VIBC1
Sequence: MTKSSELYQKAQQTIPGGVNSPVRAFNGVGGSPLFIERADGALIFDADGKAYIDYVGSWGPMILGHNHAVIREAVIDAAQRGLSFGAPTEMEIAMAELVSELVPSMEQIRMVSSGTEATMSAIRLARGFTGRDKIMKFEGCYHGHADSLLVKAGSGALTLGQPSSPGVPADFAKHTLTATFNDLGSVRELFAANKGEIACIIVEPVAGNMNCIPPVEGFHEGLREICDQEGALLIFDEVMTGFRVALGGAQAHYNIKPDLTTLGKVIGGGMPVGAFGGRKEVMQYVAPTGPVYQAGTLSGNPVAMAAGFACLNLLKEEGNEKRLAAKTKQLAEGFKVLAEKHGIPMVVNQVGGMFGFFFTDQETVTCYEDVTKCDVERFKRFFHLMLKHGVYLAPSAFEASFTSLAHGSKEIDATLEAADRCFAILAEEAK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.