PharMolix/UniProtQA huggingface dataset:
Protein: DNAK1_PARMW
Sequence: MGRIVGIDLGTTNSVVAVLEAGRPHVIANAEGGRTTPSVVGYSKDQELLVGQLARRQLVLSPRNTFSNLKRFVGRDWEELEDSSLAVPYTVRANDRGQVRVPCPVTEREYAPEELVASIIRKLVDDASTYLGESVEAAVVTVPAYFNDAQRQATRDAGRLAGIAVERILNEPTAAALAYGFDRSAVRRVLVFDLGGGTFDVSLLRIANGVFDVKATNGDTQLGGNDFDQRIVDWIADAFQAEHGVDLRRDRQALQRLTEAAEKAKQELSGVLTTPISLPFIATGENGPLHVETNLDRSTFEGLCPDLLDRLLMPVQSALRDSGWAADDIDDVVLVGGATRMPMVQQLVRTLVPLDPCQSVNPDEVVAIGAAVQAGILTGELRDLLLNDVTPLSLGLETVGGLMRVLIPRNTPIPVRQSDVFSTSEPNQSSVEIHVWQGERQMASDNKSLGRFRLSGIPPAPRGVPQVQVAFDIDANGLLQVSATDRTTGRKQSVSIQGGSNLNEDEVTALLAEAEARADEDRRKRNQIERRNRAQTLVAQAERRLRDAALELGPYGAERQQRAVEMAMRDVQDCLAQDDLQELDLCLSGLEEALFGLNRRLSAERQSDGRPLQGLRNTLGSLKDELFADDWDDDPWAAPSGPPRGRSLNRRDRDPWDDDFYR
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK1, HSP70-1, Heat shock 70 kDa protein 1, Heat shock protein 70-1.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HTF4_HUMAN
Sequence: MNPQQQRMAAIGTDKELSDLLDFSAMFSPPVNSGKTRPTTLGSSQFSGSGIDERGGTTSWGTSGQPSPSYDSSRGFTDSPHYSDHLNDSRLGAHEGLSPTPFMNSNLMGKTSERGSFSLYSRDTGLPGCQSSLLRQDLGLGSPAQLSSSGKPGTAYYSFSATSSRRRPLHDSAALDPLQAKKVRKVPPGLPSSVYAPSPNSDDFNRESPSYPSPKPPTSMFASTFFMQDGTHNSSDLWSSSNGMSQPGFGGILGTSTSHMSQSSSYGNLHSHDRLSYPPHSVSPTDINTSLPPMSSFHRGSTSSSPYVAASHTPPINGSDSILGTRGNAAGSSQTGDALGKALASIYSPDHTSSSFPSNPSTPVGSPSPLTGTSQWPRPGGQAPSSPSYENSLHSLQSRMEDRLDRLDDAIHVLRNHAVGPSTSLPAGHSDIHSLLGPSHNAPIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM
What is the function of this protein?
Transcriptional regulator.  Involved in the initiation of neuronal differentiation.  Activates transcription by binding to the E box (5'-CANNTG-3') (By similarity).  May be involved in the functional network that regulates the development of the GnRH axis (PubMed:32620954).
What are the official names of this protein?
Transcription factor 12, TCF-12, Class B basic helix-loop-helix protein 20, bHLHb20, DNA-binding protein HTF4, E-box-binding protein, Transcription factor HTF-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: KHSE_BURTA
Sequence: MAVFTAVSDADLALWMRHYDLGDVVAFRGIPSGIENSNFFLTTTHGEYVLTIFENLTAGQLPFYIDLMSHLAKHGVPVPAPVARDDGTLFGELHGKPAAIVTKLEGAAELAPGIEHCVEVGQMLARMHLAGRDYPQHQPNLRSLPWWRDAVPAIVPFITGEQRALLEGELAHQAAFFASDDYAALPEGPCHCDLFRDNALFAHAAPDTGHSVRLGGFFDFYFAGCDKWLFDVAVTVNDWCVDLSTGALDAGRADALLRAYQTVRPFTTGERRHWGDMLRAGAYRFWVSRLYDFHLPRAAQMLKPHDPGHFERILRERIAHAGALPETHACN
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: UVRC_SHESM
Sequence: MSTGFNAQSFLRTVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAEQQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISHHFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDISHTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVDEKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTESSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XAF1_MOUSE
Sequence: MEADFQVCRNCKRNVASLHFMLHEAHCLRFIVLCPECEEPIPESKMKEHMEVVHQQTKESQQHPAKCKFCELAVQLSNLDVHESHCGSRTEHCPHCNQPITLQVLSQHKAMCLSAKGRPEEGKRIVSSPGRKTRCDLCKQMIPENTYASHMKQCSAPNTVTRIRDESIIVIPSTLAFMDSGNRRSTVSKDVRPKTKNRNSSTKRETKKQNGTVALPLKSGLQQRADLPTGDETAYDTLQNCCQCRILLPLPILNEHQEKCQRLAHQKKLQWGW
What is the function of this protein?
Seems to function as a negative regulator of members of the IAP (inhibitor of apoptosis protein) family.  Inhibits anti-caspase activity of BIRC4.  Induces cleavage and inactivation of BIRC4 independent of caspase activation.  Mediates TNF-alpha-induced apoptosis and is involved in apoptosis in trophoblast cells.  May inhibit BIRC4 indirectly by activating the mitochondrial apoptosis pathway.  After translocation to mitochondria, promotes translocation of BAX to mitochondria and cytochrome c release from mitochondria.  Seems to promote the redistribution of BIRC4 from the cytoplasm to the nucleus, probably independent of BIRC4 inactivation which seems to occur in the cytoplasm.  The BIRC4-XAF1 complex mediates down-regulation of BIRC5/survivin; the process requires the E3 ligase activity of BIRC4.  Seems to be involved in cellular sensitivity to the proapoptotic actions of TRAIL.  May be a tumor suppressor by mediating apoptosis resistance of cancer cells (By similarity).
What are the official names of this protein?
XIAP-associated factor 1, BIRC4-binding protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: LIGB_PSEPK
Sequence: MPYLLLFALLFVLNTPLARAASCPHWNPQQAKAEVAQLRATLARWDEHYHRQGIALVADELYDQSHERLNHLQQCFAVGTSPSPLASARGPVPHPVPHTGVDKLADRQAVARWMTGKTGVWVQPKVDGVAVSLTYQQGRLVQLTSRGDGVHGHDWSRHIPQLGAVTRQLPEAVDLHLQGELYLRLDEHVQAKAGSANARGTVAGLLARKQLTGAQGNAIGLFVWGWPHGPEQQAERLAQLARLGFPDSQLYSIAIDTLEDAAHWREHWYRSALPFATDGVILRQGSRPPAERWQAKAPYWIAAWKYPYAQALAEVRDVRFRVGRTGRVTPVLHVQPVTLDDRRITQVSLGSLARWQRLDIRPGDQVAISLAGLTIPRLEHVVHRAVERQPITAPAPDQHHAHSCWQASEGCDEQFIARLTWLGGKQGLALPRTGPGTWRRLVEAGLVTSMTDWLQLDAERLQQAPGISRLTATQMLGSFDQARSRPFDQWLRALGVPIGKHLPLTGNWQALASRSAGQWQTVPGIGAKRSRQLVEFFAASEVQAIAAQLAEAGIEGFRTPPQRIEQ
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: IDD15_ARATH
Sequence: MRTDQVMLSNKNTNTCCVVSSSSSDPFLSSSENGVTTTNTSTQKRKRRPAGTPDPDAEVVSLSPRTLLESDRYICEICNQGFQRDQNLQMHRRRHKVPWKLLKRDNNIEVKKRVYVCPEPTCLHHNPCHALGDLVGIKKHFRRKHSNHKQWVCERCSKGYAVQSDYKAHLKTCGTRGHSCDCGRVFSRVESFIEHQDNCSARRVHREPPRPPQTAVTVPACSSRTASTVSTPSSETNYGGTVAVTTPQPLEGRPIHQRISSSILTNSSNNLNLELQLLPLSSNQNPNQENQQQKVKEPSHHHNHNHDTTNLNLSIAPSSSYQHYNNFDRIKEIMASEQIMKIAMKEKAYAEEAKREAKRQREIAENEFANAKKIRQKAQAELERAKFLKEQSMKKISSTIMQVTCQTCKGQFQAVAVPAATADETSLVVSYMSSANTDGELENGF
What is the function of this protein?
Transcription factor involved in inflorescence stems gravitropism, probably by regulating starch accumulation in amyloplasts of graviperceptive cells.  Required for stem circumnutation movements.  Regulates lateral organ morphogenesis and gravitropic responses (PubMed:24039602).  Acts cooperatively with IDD16 to control silique and branche orientation (PubMed:24039602).  Involved in the establishment of auxin gradients through the regulation of auxin biosynthesis and transport (PubMed:24039602).
What are the official names of this protein?
Zinc finger protein SHOOT GRAVITROPISM 5, Protein indeterminate-domain 15, AtIDD15.
Protein: RS10_BURVG
Sequence: MQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: FABI_RICPR
Sequence: MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEVLEKRVKPLAEEIGCNFISELDVTNQKSISNLFNDIKEKWNSFDFLLHGMAFANKNELKGRYVETSLENFHNSLHISCYSLLELSRSAETLMHNGGSIVTLTYYGAEKVIPNYNIMGVAKAALEASVKYLANDMGENNIRVNAISAGPIKTLASSAISDFSTMLKSHAATAPLKRNITQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIIGSSKLL
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: CCME_METSB
Sequence: MTRKQKRLALIASGAVVVSLAVGLVMFALRDNIVFFYSPTELAEKPATNGARLRIGGLVKPASLDRQGDQTVRFTVTDMKHDVAVTYTGLLPDLFREGQGVVAEGALRPDGVFHADSVLAKHDERYMPREVADALKKQGVWQEEGKSEGKPSAIPAQTAPQGAQAY
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: CYB_ARCTR
Sequence: MTNIPKSHPLVKIVNESFIDLPAPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGMYYGSYTFLETWNIGILLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIISALAVVHLLFLHETGSNNPSGLTSDSDKIPFHPYYMIKDILGILLLILMLLLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAIIPLLHTSKQRSMMFRPFSQCLFWLLVADLLILTWIGGQPVEYPFITIGQLASILYFSILLILMPISSIIENHFLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PYRD_SHEHH
Sequence: MFYKIAQKFMFQMDPELAHNLAIGSLKSTGNSPLNCFYAQNIKPAPVTMMGLTFPNPVGLAAGMDKDGECIDAFHAMGFGHIEVGTVTPRPQPGNDKPRCFRLKPAKAIINRMGFNNKGVDNLVENLKAVKTNAMVGVNIGKNKDTPVEQGKDDYLICMDKVYPYAAYIAVNISSPNTPGLRSLQYGDLLDDLLGSLKQKQKELAEKHGKYVPIALKIAPDLSSEEIEKIAEALIKSEFDAAIATNTTLTRDGVSGLLNANEAGGLSGKPLNSLSTIVIKQLADCLKGKLPIIGVGGINAAEDALDKLDAGAEMVQIFSGFIYQGPKLIKDIVEAYRIK
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PDIA3_PAPHA
Sequence: SDVLELTDDNFESRVSDTGSAGLVEFFAPDATANDVPSP
What is the function of this protein?
Disulfide isomerase which catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds (By similarity).  Associates with calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells (By similarity).  Association with calcitriol does not affect its enzymatic activity (By similarity).
What are the official names of this protein?
Protein disulfide-isomerase A3, 58 kDa glucose-regulated protein, 58 kDa microsomal protein, p58.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum lumen. Melanosome.
Protein: MURC_MYCSS
Sequence: MSTPPLPDELRRVHMVGIGGAGMSGIARILLDRGAMVSGSDAKESRAVVALRARGAAIRIGHDASSLDLLPGGPTAVVTTHAAIPKTNPELVEARRRAIPIVLRPVVLAKLMAGHTTLMVTGTHGKTTTTSMLIVALQHCGFDPSFAVGGDLGEAGTNAHHGSGECFVAEADESDGSLLEYTPDVAVVTNIEADHLDFFGSAEAYTAVFDAFVERLTPGGALIACVDDPGSAALAERTAALGVRVLRYGSAGGRDLAGALVGWEQQGTGAVAHIQLAGESAPRAMRLSVPGRHMALNALGALLAALQVGADPDTVLDGLAGFEGVRRRFELVGTATGVRVFDDYAHHPTEVAATLAALRAVTDQAGDGRAVVVFQPHLYSRTETFAREFGAALSAADLVFVLDVYGAREQPIAGVSGASIVEHVGVPVTYVPDFSAVAAQVAGAVRPGDVVVTMGAGDVTMLGPEIIAALQARANRTVPGAGAR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1C_LIRTU
Sequence: MKEQKLIHEGLITESLPNGMFRVRLDNEDLILGYVSGRIRRSFIRILPGDRVKIEVSRYDSTRGRIIYRLRNKDSND
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TFPI2_HUMAN
Sequence: MDPARPLGLSILLLFLTEAALGDAAQEPTGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWRIEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATCMGFCAPKKIPSFCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFVSREDCKRACAKALKKKKKMPKLRFASRIRKIRKKQF
What is the function of this protein?
May play a role in the regulation of plasmin-mediated matrix remodeling.  Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa.  Has no effect on thrombin.
What are the official names of this protein?
Tissue factor pathway inhibitor 2, TFPI-2, Placental protein 5, PP5.
What are the subcellular locations of this protein?
Secreted.
Protein: PUP_BIFLD
Sequence: MPQQFEQPQAQQAATQEDDALATTQAAAQTESADQADVLDDILDDIESTLETNAEEYVNSFVQKGGE
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: Y6538_BACAN
Sequence: MVVLKLGKNYPIDRDSRGRYRHSYVFMRGANVEVKLLNHEELLKGKITTIEEYYCVLDVEGTSGSYQVTVNFSEVKYIKHEEFPTVEERSPKYSKGDKKTSFVFKIGEKIGCVFKDGKGIKGTLLSEDAYYLYVKSEKENYYTIMKGALSYIAHVKHEPLLLTNDFYTEEMKLADYKKPTEYVFSVGDTITVYFPSGKNVSGVVLDESKYWVLLQTEKRQITIFKGSYSYFKHETYETKAYLYVENRKLRKQLRSGDTN
What are the official names of this protein?
Uncharacterized protein pXO2-37/BXB0038/GBAA_pXO2_0038.
Protein: PDRP_RHORT
Sequence: MSMQSHHVHLVSDATGETVSNVVRACLAQFEDVRVVQHRWWLLRSPSQVGRVIEGIQRDPGTVVFTVVDPEIRRALEEACRLINIPCVALLDPVMDALALVLETKGNQQPGRQYTLDEGYFSRIEAMHFALALDDGQSLDRLKQAEVVVVGVSRTSKTPTCMFLANKGIRAANVPLVPGIDPPAELMDLAGPLVVGLTRDPKSLSDMRRSRLRLMREDGDSPYAEEDSVAREVREARRLYARMGWTVIDVTRKSIEEVAATIMQKLGTAPWGEGL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: CLPB_CORDI
Sequence: MAGFNPTTKTQEALQEALQKASAAGNPDIRPEHLLAAILGQEDGIAIPVLRATGVDPDVVRREAEALVAKLPKAEGANLANPNFNRDALSVLNNAQELAGELGDEYVSTEVLLAAVARGTNDAAELLTKRGATYDVIKGVFPSVRGNKKVTTESPEDQFQALEKYSTDLTARAREGKIDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVAGDVPESLKGKTLISLDLGSMVAGAKYRGEFEERLKAVLDEIKSAEGEIITFIDELHTIVGAGATGDSAMDAGNMIKPLLARGELRLVGATTLDEYRKYIEKDAALERRFQQVFVGEPSVEDAVGILRGLKERYEVHHGVRIQDSALVAAATLSDRYITSRFLPDKAIDLVDEAASRLRMEIDSSPQEIDELERIVRRLEIEEVALSKETDAASKDRLIKLRQELADEREKLGELVARWNNEKGAINKVREAKEELERLRSESEIAERDGDYGKVAELRYGRIPELEKQVAEAEEHTVETTMLSEEVTPDTIAEVVSAWTGIPAGKMLQGETEKLLNMEAELGKRVVGQSEAVVAVSDAVRRARAGVADPNRPTGSFLFLGPTGVGKTELAKALAEFMFDDDRAMVRIDMSEYGEKHAVARLVGAPPGYVGYDQGGQLTEAVRRRPYTVVLFDEVEKAHPDVFDILLQVLDEGRLTDGQGRTVDFRNTVLILTSNLGAGGTKDEMMDAVKRAFKPEFVNRLDDVVIFDPLSQEQLTHIVEIQIAQLAQRLAARRLTLAVSDSAKLWLAERGYEPAYGARPLRRLIQQAIGDQLAKKLLSGEVRDGSEVHVDADLDNDGLVISAS
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_PICTO
Sequence: MGKHIVAQRRGHGSLVYRSPSHRHLGDIKYPRDGTYKIEDIIQAPGRNTPVLLIRNEKNEKNYMIAFNGAYVNQEIHVGDIDSPAIGDVTYLANIPDGSYVYNIESIPGDGGKFCRAAGTAALVISHGAYVSLKLPSGVNKEFHPRCRATVGFIAGSGARDIPILKAGTHIKYLQSKAKRPYTVRGVAMNAVNHPHGGGNHQHVGRPSTVGRGTPPGRKVGRLSPKRRKKYGR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RNS2_PANGI
Sequence: GVQKTETQAISPVPAEKLFKGSFLDMDTVVPKAFPEGIKSVQVLEGNGGVGTIKNVTLGDATPFNTMKTRIDAIDEHAFTYTYTIIGGDILLDIIESIENHFKIVPTDGGSTITQTTIYNTIGDAVIPEENIKDATDKSIQLFKAVEAYLLAN
What is the function of this protein?
Catalyzes the two-stage endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
What are the official names of this protein?
Ribonuclease 2.
What is the protein family that this protein belongs to?
Belongs to the BetVI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK5_NEOYE
Sequence: MAIGLKEKYKTTVTQSLKDEFQYKNVHEVPRFTKITINRGLGEASQNAKALESSIQELTLITGQKPIVTKAKKSIAGFKIREEVPIGIVVHLRKDKMYSFLEKLINLTLPRIRDFRGISPRSFDGKGNYNLGLREQLIFPEIDYDNIDQIRGLDISIVTTAKTDQEGLALLKKLGMPFRES
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLP24_DICDI
Sequence: MRIEKCYFCSGPVYPGHGVMFVRNDCKQFRFCRSKCHKNFKLKRNPRKTRWTKAFRKLNGKEMTVDKTLEFEKKRNRPVKYDRELINNTIIAMARVQKIKERREKTFYKNRMEGVKGMQKKQKLKEINQNLSLIRGPSALNKLQERIKNNAEKIEQLTTTKMQS
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  Ensures the docking of nog1 to pre-60S particles.  Activates and recruits ATPase AFG2 to cytoplasmic pre-60S ribosomal particles.
What are the official names of this protein?
Probable ribosome biogenesis protein RLP24.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL24 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: RL16_ROSS1
Sequence: MLMPKRVKYRKQQRGHNRGMAHRGNTVAFGEYGLMALEATWMTSRQIEAARRAISHHVKRGGKIWIRIFPDKPVTAKPAETRMGSGKGAVDHYVAVIKPGRILFELAGVRPEVAHEALERAAQKLPIKCKIVPREDLEGAA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: EF1B_THEGJ
Sequence: MSDYNMVAVVKVMPTDPEVNLDELEAKLKEVLPEKFGLAKVEREPIAFGLVALKFYVLAKDEEGYDLDQVLEAFRQVENVESAEVETVSRI
What is the function of this protein?
Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, aEF-1beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: MTNW_GEOTN
Sequence: MSTVIATYLLHDEKDIRKKAEGIALGLTVGTWTDLPALEQEQLRKHKGEVVGIEELGESGPANEYFDKRLKRAIVKIAYPTVNFSADLPALLATTFGKLSLDGEVRLLDLELSDEWKRHFPGPRFGIAGIREKVGVYDRPLLMSIFKGIIGRDLAYLTSELKKQALGGVDLVKDDEILFDNELLPFEKRITAGKAALQEVYEQTGKRTLYAVNLTGKTFELKEKAKRAAELGADVLLFNVFTYGLDVLQGLREDENINVPIMAHPAFSGAMTPSEFYGVAPSLLLGKFLRLAGADFVLFPSPYGSVALEREQALGIARALTDEQEPFARAFPVPSAGIHPGLVPLLVRDFGLDCIVNAGGGIHGHPDGAIGGGQAFRAAIDAALAGRLLREAVKENEALQKAIDRWGAIEVEA
What is the function of this protein?
Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
What are the official names of this protein?
2,3-diketo-5-methylthiopentyl-1-phosphate enolase, DK-MTP-1-P enolase, RuBisCO-like protein, RLP.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: VSP2_TRIST
Sequence: MVLIRVLANLLIIQLSYAQKSSELVIGGDECNINEHRSLVVLFNSSGALCGGTLINQEYVLAAAHCDMPNMQILLGVHSASVLNDDEQARDPEEKYFCLSSNNDTKWDKDIMLIRLNRPVNNSVHIAPLSLPSSPPSVGSVCRIMGWGKTIPTQETHPDVPHCANIKLFHYSLCRAVYVGMPAQSRILCAGILQGGIGSCQGDSGGPLICNGQFQGIVSATSKPCAHSLMPALYIKVFDYTDWIKSIIAGNTTVTCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease CL2, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.