PharMolix/UniProtQA huggingface dataset:
Protein: DCMC_MOUSE
Sequence: MRGLGPGLRARRLLPLRSPPRPPGPRGRRLCGGLAASAMDELLRRAVPPTPAYELREKTPAPAEGQCADFVSFYGGLAEASQRAELLGRLAQGFGVDHGQVAEQSAGVLQLRQQAREAAVLLQAEDRLRYALVPRYRGLFHHISKLDGGVRFLVQLRADLLEAQALKLVEGPHVREMNGVLKSMLSEWFSSGFLNLERVTWHSPCEVLQKISECEAVHPVKNWMDMKRRVGPYRRCYFFSHCSTPGEPLVVLHVALTGDISNNIQGIVKECPPTETEERNRIAAAIFYSISLTQQGLQGVELGTFLIKRVVKELQKEFPQLGAFSSLSPIPGFTKWLLGLLNVQGKEHGRNELFTDSECQEISAVTGNPVHESLKGFLSSGEWVKSEKLTQALQGPLMRLCAWYLYGEKHRGYALNPVANFHLQNGAVMWRINWMADSSLKGLTSSCGLMVNYRYYLEETGPNSISYLGSKNIKASEQILSLVAQFQNNSKL
What is the function of this protein?
Catalyzes the conversion of malonyl-CoA to acetyl-CoA.  In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid synthase and that fatty acids with multiple methyl side chains are produced.  In peroxisomes it may be involved in degrading intraperoxisomal malonyl-CoA, which is generated by the peroxisomal beta-oxidation of odd chain-length dicarboxylic fatty acids.  Plays a role in the metabolic balance between glucose and lipid oxidation in muscle independent of alterations in insulin signaling.  Plays a role in controlling the extent of ischemic injury by promoting glucose oxidation.
What are the official names of this protein?
Malonyl-CoA decarboxylase, mitochondrial, MCD.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion matrix. Peroxisome. Peroxisome matrix. Note=Enzymatically active in all three subcellular compartments.
Protein: SIP5_COCIM
Sequence: MGNAATKESRSSQEHSARHSRGGSTASTAAYDHYRPSDGIHASSSRALRGGRSDFALLGLGAEREPVEHRRETRQEREARKREKENAARIKERQRSMKEEHVDGGYLVTQGVYVGTEDFNKAIVRQLMIERRLAPFWRGLNDFSESWTEHQLMAAARGMPIPAPDEVPPELEYKIPSKSSAEKQPPERNLNTLMVPITSRSQSYNSDTSSINRTISPARSPGALSPTNSFLRGRAKTLASLTTSSKTPASDMAPRELQLPKDPFVNGQPIEAYLYKDASECPICFLYYPPYLNKTRCCDQPICSECFVQIKRPDPHPPEHHDPNNSETTHPDEPEGQLVSEPAACPFCVQPEFGVMYTPPPFRRGLAYAASPGVHALANSSAASSASSLVSGGANPGTRRRAVSISADSPSVITTDRVRPDWATKLAAARAQAARRSAAATALHTAAYMMNNPGGPGEPRRRGMLRRTAGQDSPGGRTAPSHVNAMAYLAERRVVTDRDNASPVDSTTNLAPPRASSRRSRIDELEEMMMMEAIRLSLAAEEERRKKEEKETRKEAKRREKEAKKAEKSAKKAGLDSQNPSNLTSSTSSANSAVQTAGGANSELDMSANKGKGVDRSEPRPGVSTEAGSSTEPPKITIKDLKGEQFSSMLEGSSKNMHLRHVSSASSSNSSLVESAFGESIGSGTPHNGSSSSLAAIHGFRSLAAMIDDTPSGDSGESMNRPGSTNEQVQGAPAVKEPSENSAPNEPDQVTLLSSSPSLEQKDTLGKEVHMSSAEVLPQSSLGTAS
What is the function of this protein?
May negatively regulate the SNF1 kinase.
What are the official names of this protein?
Protein SIP5.
What is the protein family that this protein belongs to?
Belongs to the SIP5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECD_SALCH
Sequence: MLNRYPLWKYIMLVVVIIVGLLYALPNLYGEDPAVQITGVRGVAASEQTLIQVQKTLQEEKIPAKSVALEEGAILARFDTTDTQLRAREALMSVLGDKYVVALNLAPATPRWLAAIHADPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLREKGIPYTTVRKENNYGLSITFRDSKARDEAIAYLTPRHRDLVISSQSGNQLRAVMTDARLSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAAAGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQSRLGNSFRITGISNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIKQGLEACLAGLVVSILFMIFFYKKFGLIATSALVANLVLIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAINEGYAGAFSSIFDANITTLIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIIGTRAIVNLLYGGKRVTKLSI
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OX2G_PONAB
Sequence: MERLVIRMPFCHLSTYSLVWVMAAVVLCTAQVQVVTQDEREQLYTPASLKCSLQNAQEALIVTWQKKKAVSPENMVTFSENHGVVIQPAYKDKINIAQLGLQNSTITFWNITLEDEGCYMCLFNTFGFGKISGTACLTVYVQPIVSLHYKFSEDHLNTTCSATARPAPMVFWKVPRSGIENSTVTLSHPNGTTSVTSILHIKDPKNQVGKEAICQVLHLGTVTDFKQTVNKGYWFSVPLLLSIVSLVTLLVLISILLYWKRHRNQDREP
What is the function of this protein?
Costimulates T-cell proliferation.  May regulate myeloid cell activity in a variety of tissues (By similarity).
What are the official names of this protein?
OX-2 membrane glycoprotein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: BNZE_PSEPU
Sequence: MRLEGEVALVTGGGAGLGRAIVDRYVAEGARVAVLDKSAAGLEALRKLHGDAIVGVEGDVRSLDSHREAVARCVEAFGKLDCLVGNAGVWDYLTQLVDIPDDLISEAFEEMFEVNVKGYILAAKAALPALYQSKGSAIFTVSNAGFYPGGGGVLYTAGKHAVIGLIKQLAHEWGPRIRVNGIAPGGILGSDLRGLKSLDLQDKSISTFPLDDMLKSVLPTGRAATAEEYAGAYVFFATRGDTVPLTGSVLNFDGGMGVRGLFEASLGAQLDKHFG
What are the official names of this protein?
Cis-1,2-dihydrobenzene-1,2-diol dehydrogenase, Cis-benzene glycol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CHT_PENRW
Sequence: MVPVLKKYKAAAVNAEPGWFDLQESVRRTIHWIDEAGKAGCKLIAFPELWIPGYPYWAWKVNYQESLPLLKKYRENSLPSDSDEMRRIREAAKANKIWVSLGYSELDLASLYTTQIMISPAGDVINHRRKIKATHVERLVFGDGTGDTTESVMDTEIGRIGHLNCWENMNPFLKAYAASLGEQVHIAAWPLYPGKETLKYPDPYTNVAEANADLVTPAYAIETGSFTLAPWQTITAEGIKLNTPPGKELEDPNIYNGNGRIFGPDGQNLVPHPDKDFQGLLFVDIDLDEIHLTKSLADFGGHYMRPDLIRLLVDTNRKDLVVHEDRVNGGVAYTRTIDRVGLSAPLDASATEAQSESV
What is the function of this protein?
Catalyzes the hydration of cyanide to formamide.  Degradation of cyanide may be important for plant pathogenic fungi in infection of cyanogenic plants.
What are the official names of this protein?
Cyanide hydratase, CHT, Cyanide-degrading nitrilase, Formamide hydrolyase, NitPc1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.
Protein: ARGB_STUS1
Sequence: MTLSREAATQFAKVLSEALPYIRRFVGKTLVIKYGGNAMESEELKTGFARDIVLMKAVGINPVVVHGGGPQIGDLLKRLNIESHFIDGMRVTDSQTMDVVEMVLGGQVNKSIVSLINQHGGSAIGLTGKDAGLIRARKLKATRQTPEMTKPEIIDIGHVGEVTGVNAELLEMLVQGNFIPVIAPIGVGENGESYNINADLVAGKVAEALKAEKLMLLTNIAGLMDKQGNVLTGLSTAQVDALIADGTIYGGMLPKIRCALEAVQGGVNSAHIIDGRVPNAVLLEIFTDVGVGTLITNSQR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
Protein: RPOA_BEUC1
Sequence: MLIAQRPTLTEEVVADNRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTEIILNIKNIVVSSENDEPVVMYLRKQGPGVVTAADITPPAGVEVHNPDLHIATVNGKGKLEVELTVERGRGYVSAQQNKAYDTEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIVDVESKPAISPRDAVASAGKTLVELFGLARELNTAAEGIEIGPSPTDAALAADLALPIEDLDLTIRSYNCLKREGIHQVGELVARSEADLLDIRNFGAKSITEVKEKLAALGLSLKDSPADFDPSLVTDAYDGDLDADYADEQYN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL15_AERPE
Sequence: MVVRRRKKSRKLRGRTRTMSWGRIGQHRKSGSKGGYGAAGLGKHEWTWTIKYAPTWYGKKGFNPPRIRAGLEVTTINVGQLDEIAALLEAQGKAEKEDGKIVVNLEKLGIHKLLGEGRVARPLKVITPLASELAIKKIEEAGGEVIVTRATREEAEES
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: MRAY_BACVZ
Sequence: MLEQVILFTIIMGFLISVLISPILIPFLRRLKFGQSIREEGPKSHMKKSGTPTMGGVMIIVSIAITAIVMTQKFSHLSAEMFLLLFVTIGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIIIAIVFYGVYHYCHFSTGIRVPGTHLSIDLGWGYFILVLFMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGAIVTVAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVTFWTAGLLLAVLGIYIEVWL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS1_SHIB3
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYW_HAEDU
Sequence: MTKSIVFSGVQPSGELTIGNYLGALRNWVTLQDDYDCLFCIVDLHAITVRQDPIALRKSTLDVLALYLACGIDPNKSTIFIQSQVPEHSQLAWVLNCYTYFGEMGRMTQFKDKSARYEENVNVGLFTYPVLMAADILLYQANQVPVGDDQKQHLEITRDIANRFNTLYGKKDAEGKLIESVFTVPECFIAKACARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKAVAKKIKRAMTDSDEPPVIKYDQKNKAGVSNLLDILAAITGKSMVELEAEFEGKMYGHLKTEVADQVMAMLTGLQERYQRFRQDEALLEKIYRDGAEKARMRAKKTLDEVYKLIGFVG
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTAB_BACSU
Sequence: MKKIVGALAVFVITYALFSAAGYLFPVDQEWYNSLKKPDWTPSGTAIGIIWAILFALISLSAAIVYAAFSFKGAKSFWFTLLINYVLNQAFSYFQFTQKNLLAASLDCLLVAITAIVLLIIAKKYSRAASYLLLPYFLWSAFATFLSFTINSMNL
What are the official names of this protein?
Uncharacterized membrane protein YtaB.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS13_SYNWW
Sequence: MARIAGVDLPRDKRIEVSLTYIFGIGRSSSRKILTDAGINPDTRVKDLTEEEVSKLREIIEKEYHVEGDLRRQVNMDIKRLMDLGCYRGIRHRRGLPVRGQNTKTNARTRKGPKRTAGGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GA45B_BOVIN
Sequence: MTLEELVACDNAAQKMQTVSAAVEELLVAAQLQDRLTVGVYESAKLMNVDPDSVVLCLLAIDEEEEDDIALQIHFTLIQSFCCENDIDIVRVSGMQRLAQLLGEPAETQGTTEARDLHCLLVTNPHTDTWKSHGLVEVASYCEESRGNNQWVPYISLQER
What is the function of this protein?
Involved in the regulation of growth and apoptosis.  Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK (By similarity).
What are the official names of this protein?
Growth arrest and DNA damage-inducible protein GADD45 beta.
What is the protein family that this protein belongs to?
Belongs to the GADD45 family.
Protein: GATB_BRASB
Sequence: MTATSGKLMKGATGDWEVVIGMEIHAQVTSKSKLFSGASTAFGGDPNSHVSLVDVAMPGMLPVINEECVRQAVRTGLGLNAKINLRSVFDRKNYFYPDLPQGYQISQYKDPIVGEGEVTVELDGGKTATIGIERLHLEQDPGKMLHDQSPSLSYIDYNRCGVALMEIVSKPDIRDAEQAKAYVTKLRSILRYLGTCDGDMEKGSLRADVNVSVRKPGGPLGTRCEIKNINSISFIGQAVEAEARRQIEIIEDGGTIEQETRRFDPDKGETRSMRSKEEAHDYRYFPDPDLLPLEFDQAFVDALKAALPELPDQKKARFIADFGLSPYDASVLVAERESAAFYESVLEALSDRGRDGKLAANWVINELFGRLNKEGRDIASSPVSSAQLAAIVALIGEGTISGKIAKDLFEIVWSEGGDPRELVESRGMKQVTDLGAIEKVVDEIIAANPDKVAQAKAKPQLAGWFVGQVMKSSGGKANPQAVNDLLKSKLGI
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: UPP_SALPA
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLVAAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: HSLO_NEIMA
Sequence: MNQTAINRADVRTRFIFDDMPVRGLHVRLENVWQHIVKQKNYPAAIRRALGELLAAGVLLSGNLKNEGTLIVQVQGQGRLKMLVAEATSDRTVRATARWDETAEIADDESLGDLLGEGGVFVLTLQPKDGEPWQGVVPLEGDGIAQMLVNYMKRSEQLDTHIVLSASDEAAGGLLVQRLPEEVLDEEAWEHVSTLARTLTAEELAGLDAQHVLYRLFHETPPRVFEPETFEFSCTCSRGKVSDMLLMLGGEEVGGVVVEQGSIEVDCDFCHSKYVFDETDVNALFGEDVVGVAKGLPRHTVQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_PARL1
Sequence: MFAVIRTGGKQYRVAKDDVLEVERNGGEAGDKIDLEVLMLGGEGGTLKVGAPLVDGAKVKAEIVEHTRGPKITIFKKRRRQNYRRKNGHRQDLMLVKILDIAG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: DNLI_THEAC
Sequence: MLFSVVADAFEKMESTTKRLELTDLLVNLLKEADDDLPLLIYLLEGKLGPDYLGIETQMSDKLIIKALSVASNISEDEIAKEYAKAGDIGTIAKEIAEKRSLRSLVQEEMTVKYIHDTLMKMARTTGSGSTKARVDAYMDLFLNSTPKEIMYITRIITGKLRIGISDATILDAIVKAFADEKYSEDIENAFNFHPDLGYIASELRKGNIDAILKLGPTPMIPFKVMLAERLRSVEEILEKMGGRCAFEYKYDGMRTETHIERGKVRLFSRGNEETTNQFPDITKAASETFKVDSAILDGEAVPYDPDTGELYPFQVISHRRGRKYDLDKVSSEIPITVFLFDIVYLNGRDLSKTPYTERRKILESIFTESDSFRLAKRIESGDPAEVHRFFNSAIEDGCEGLVAKSTSPDSFYKAGARGWLWIKLKRDYQAQLWDTLDLTVVGAFYGHGRRKGTYGALLLATYNDKNDTFETVCKLGSGFSDDVLFSLPKKFEQYVSKEKPARVISNLEPDVWFYPAVVMEVIGAEITVSPIHTCAYGEIEKDSGLSVRFPRFTGKWREDKKPEDSTTSREILEMYKEQKKTITEEKS
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: ISPF_PELPB
Sequence: MRIGIGIDVHPFAEGRKLVIGGVHIPGHNGLDGHSDADVLLHAVSDALLGAAALGDIGLHFPNTSQEFKDIDSMILLKQVRKLLEKHGYQTVNIDAMLLLEEPKIAPYITGMRKNIARCLDIEIGMVSVKATTNEKLGYIGREEGAAAHAVCIIRSL
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RECA_HAEIE
Sequence: MATQEEKQKALAAALGQIEKQFGKGSIMKLGDTKTLDVESISTGSLGLDVALGIGGLPMGRIVEIFGPESSGKTTLTLSVIAQAQKAGKTCAFIDAEHALDPIYAAKLGVDVKELFVSQPDNGEQALEICDALVRSGAIDVIIVDSVAALTPKAEIEGDMGDSHMGLQARLMSQALRKLTGQIKNANCLVVFINQIRMKIGVMFGNPETTTGGNALKFYSSVRLDIRRTGSVKDGENIIGNETRVKVVKNKLAAPFRQVDFQILYGEGISKAGELLELGVKHKLVEKSGAWYSYNGEKIGQGKANSMKWLNENIEKSDELEARLRAELVANPEQALMADIEQSENNTESESDFE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEFG_YERPB
Sequence: MLQPPKVLLLYAHPESQDSVANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRDHQVIVFQHPLYTYSCPALLKEWLDRVLARGFANGVGGHALTGKHWRSVITTGEQEGTYRIGGYNRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKPETLASHAQAYVQWLQSPLTRGL
What is the function of this protein?
Regulatory subunit of a potassium efflux system that confers protection against electrophiles.  Required for full activity of KefB.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system ancillary protein KefG, Putative quinone oxidoreductase KefG.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RS16B_YEAST
Sequence: MSAVPSVQTFGKKKSATAVAHVKAGKGLIKVNGSPITLVEPEILRFKVYEPLLLVGLDKFSNIDIRVRVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEQSKNELKKAFTSYDRTLLIADSRRPEPKKFGGKGARSRFQKSYR
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S16-B, RP61R, Small ribosomal subunit protein uS9-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHLB_ECOLU
Sequence: MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHADAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEYIEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLTRPRTGNGPRRTGTPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S14_LATCO
Sequence: MKTLLLTLVVVTTVCLDLGYTRRCFNQQSSQPKTTKSCPLGENSCYNKQWRDHRGSITERGCGCPKVKPGIKLRCCESEDCNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin NCA-04.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DUSA_XANAC
Sequence: MTASTDRYAASLRLSVAPMMDWTDRHCRVFHRLLAPSARLYTEMVHANAVIHGDRARLIGFDPVEHPLALQLGGSDPALLAQAAAIAQEWGFDEINLNCGCPSDRVQAGRFGACLMREPALVAECVAAMCAATHLPITVKCRLGVDDDDDYALFARFVDQVVAAGAAMVVVHARNAWLKGLSPKENREVPPLRYDWAYRLKQERPGLPVVLNGGIVAVEPAIAHLQHADGVMLGRAAYHDPYVLHCLDAALNQRPEQPRESLLRAYQPYVESQLAQGLGLKHMTRHVLGLFHGQPGGRAFRQVLSEGAHRPGAGWELVEQALERTDTRSWRVVA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U20 and U20a in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(20/20a) synthase, U20-specific dihydrouridine synthase, U20-specific Dus, tRNA-dihydrouridine synthase A.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusA subfamily.
Protein: CHLL_ANGEV
Sequence: MKIAVYGKGGIGKSTTSCNISIALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQSKDYHYEDVWPEDVIYKGYGGVDCVEAGGPPAGAGCGGYVVGETVKSLKELNAFYEYDIILFDVLGDVVCGGFAAPLNYADYCIIITDNGFDALFAANRIAASVREKAHTHPLRLAGLVGNRTSKRDLIDKYVEACPMPVLEVLPLIEDIRVSRVKGKTLFEMAESQPTLNYVCEFYLNIADQILSQPEGVVPKEIPDRELFSLLSDFYLNPINSGKNENIENNLHDFMII
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DLAA_AMYME
Sequence: VGTRVVRIEDQQLITQGGTYVEDL
What is the function of this protein?
Active with aldehydes and formate esters as substrates.
What are the official names of this protein?
DYE-linked aldehyde dehydrogenase, alpha chain, DL-ALDH.
Protein: TRP6_ARATH
Sequence: MVDCGVDIYQLPVVPRACRSPRGRRLKIMRKQRSEFEVLAQVAGRFSGERKNRIVIGSLAHETKETKDDNVVVNNFLETMEVEVKPQPGLENLSQVLLSKDWLALGPSMPNSPITQEENFDSRSKIDSKRKVSHLKERGSCISQESQNMYPLKKRKLFYQNHSSESHDTPCTVKFGIKSLNISELLVDVPESATVGSLKLAVLEAVTQILKGGLNIGVLFQGKTIVDDSKTLLQIGIPYDDDDDENLGSLGFMLEPQKSETTTITTFTTVSPRTRLRQNQVLGSVDSTEAVAAKSVVPVRMKPAWQPEMVQRRIRRPFTVSEVEALVQAVERLGTGRWRDVKSHAFNHVNHRTYVDLKDKWKTLVHTAKISARQRRGEPVPQDLLDRVLAAHAFWSDRTG
What is the function of this protein?
Binds specifically to the plant telomeric double-stranded DNA sequences.  At least 4 repeats of telomeric sequences are required for binding.
What are the official names of this protein?
Telomere repeat-binding protein 6, Protein TRF-LIKE 4.
What are the subcellular locations of this protein?
Nucleus.