PharMolix/UniProtQA huggingface dataset:
Protein: RLMF_SALTY
Sequence: MSAQKPGLHPRNRHQHRYDLAALCQTTPELTSFLIRTPAGEQSVDFANPQAVKALNKALLAHFYAVTHWDIPPGFLCPPVPGRADYIHHLADLLGETTGSIPAQATILDVGVGANCIYPLIGVHEYGWRFTGSEVSDAAMSSAQAIIQANTGLSRAIRLRRQKDPAAIFTGIIHKNEFYDATLCNPPFHDSAAAARAGSERKRRNLGQNKDDALNFGGQQQELWCEGGEVAFIKKMIAESQSFRRQVLWFTTLVSRGENLPPLYRALTEAGAVKVVKKEMAQGQKQSRFIAWTFMDDDQRRRFITRKR
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHAA_RHOSO
Sequence: MSEIGTGFPFDPHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYLWRNIIPHVAPSHRCIAPDLIGMGKSDKPDLDYFFDDHVRYLDAFIEALGLEEVVLVIHDWGSALGFHWAKRNPERVKGIACMEFIRPIPTWDEWPEFARETFQAFRTADVGRELIIDQNAFIEGALPKCVVRPLTEVEMDHYREPFLKPVDREPLWRFPNELPIAGEPANIVALVEAYMNWLHQSPVPKLLFWGTPGVLIPPAEAARLAESLPNCKTVDIGPGLHYLQEDNPDLIGSEIARWLPAL
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 2 subfamily.
Protein: VL2_HPV41
Sequence: MLARQRVKRANPEQLYKTCKATGGDCPPDVIKRYEQTTPADSILKYGSVGVFFGGLGIGTGRGGGGTVLGAGAVGGRPSISSGAIGPRDILPIESGGPSLAEEIPLLPMAPRVPRPTDPFRPSVLEEPFIIRPPERPNILHEQRFPTDAAPFDNGNTEITTIPSQYDVSGGGVDIQIIELPSVNDPGPSVVTRTQYNNPTFEVEVSTDISGETSSTDNIIVGAESGGTSVGDNAELIPLLDISRGDTIDTTILAPGEEETAFVTSTPERVPIQERLPIRPYGRQYQQVRVTDPEFLDSAAVLVSLENPVFDADITLTFEDDLQQALRSDTDLRDVRRLSRPYYQRRTTGLRVSRLGQRRGTISTRSGVQVGSAAHFFQDISPIGQAIEPIDAIELDVLGEQSGEGTIVRGDPTPSIEQDIGLTALGDNIENELQEIDLLTADGEEDQEGRDLQLVFSTGNDEVVDIMTIPIRAGGDDRPSVFIFSDDGTHIVYPTSTTATTPLVPAQPSDVPYIVVDLYSGSMDYDIHPSLLRRKRKKRKRVYFSDGRVASRPK
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: FGD3_PONAB
Sequence: MESGGGSSTPPGPIAALGMPDSGPGSSSLGKLQALPVGPRAHCGDPGSLAAAGDGSLDTGSTGELSGSLKIPNRDSGIDSPSSSVAGENFPCEEGLEAGPSPTVLGAHPEMALDSQVPKVTPREEADSDVGEEPDSENTPQKADKDAGLAQHSGPQKLLHIAQELLHTEETYVKRLHLLDQVFCTRLTDAGIPPEVIMGIFSNISSIHRFHGQFLLPELKTRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAVGLVSTWTQRSPLFKDVVHSIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPQDAPDQKDAERSLELISTAANHSNAAIRKVEKMHKLLEVYEQLGGEEDIANPANELIKEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKFSVREKMDISGLQVQDIVKPNTAHTFIITGRKRSLELQTRTEEEKKEWIQIIQATIEKHKQNSETFKAFGGAFSQDEDPSLSPDMPITSTSPVEPVVTTEGGSGAAGLEPRKLSSKTRRDKEKQSCKSCGETFNSITKRRHHCKLCGVVICGKCSEFKAENSRQSRVCRECFLTQPVAPESPSPEAPAKPRRSTEKTPTADPQPSLLCGPLRLSESGETWSEVWAAIPMSDPQVLHLQGGSQDGWLPRTIPLPSCKLSVPDPEERLDSGHVWKLQWAKQSWYLSASSAELQQRWLETLSTAARGDTAQDSPGALQPQVPTGAAAP
What is the function of this protein?
Promotes the formation of filopodia.  May activate CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP.  Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).
What are the official names of this protein?
FYVE, RhoGEF and PH domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: DEF51_ARATH
Sequence: MGFTKILVTFFLVGLLVISSSPQNAIASEIKAKINGLECFNTCTSYYDDHKCNVDCLSSGYPAGECYTVSPSQPKKCCCY
What are the official names of this protein?
Defensin-like protein 51, Low-molecular-weight cysteine-rich protein 48, Protein LCR48.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_STRP3
Sequence: MANILRKVIENDKGELRKLEKIAKKVESYADQMASLSDRDLQGKTLEFKERYQKGETLEQLLPEAFAVVREAAKRVLGLFPYRVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNAIAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKSPAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADMFVKTLTSVDYVIDVPTKTIGLSDSGIDKAESYFNLSNLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQFTGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIARIDHTDLLYPTLESKFRAVVEDVKTRHAKGQPILVGTVAVETSDLISRKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLDRMKLDEEDTVIKSGMLGRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDRAVDAHARSNRKDAVDAIVTFARTSLVPEESISAKELRGLKDEQIKEKLYQRALAIYDQQLSKLRDQEAIIEFQKVLILMIVDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQRATTAAPQNIQSQQSANTDDLPKVERNEACPCGSGKKFKNCHGRKSFS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PSBU_SYNPW
Sequence: MKRLLSWLTGLVVMAGLLFSLATPSGVQAADIRNVADDKIAERGDKVDLNNSSVRRFQQFPGMYPTLAGKIVLGGPYESVDDVLALDLTDRQKELFEKYRDNFTVTAPSIALNEGFDRINDGQYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the Lumenal side of the thylakoid membrane.
Protein: YDJC_MOUSE
Sequence: MAFPRVRLVVTADDFGYCPRRDEGIVEAFLAGTVTSVSLLVNGTAAESAAELARRHSIPTGLHANLSEGRPVGPARHNASSLLSPEGFFLGKMGFREALAAGDVALPQVREELEAQLSRFRELLGRSPTHVDGHQHVHVLPGVCQVFAEALQAYGVRFTRLPAERGVGSCAWLEAPARAFACTVERDARAAIGPFSRHGLRWTDAFVGLSTCGRHMSAHRVLGSLARALEDIPAGHALTAELMAHPGYPSVPPAGGCGEGPDAFSCSWERLHELHVLTAPTLRAWLAQNGVQLCAIDDLDSKRPGEGVPL
What is the function of this protein?
Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
What are the official names of this protein?
Carbohydrate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family.
Protein: NUD19_MUSCR
Sequence: MSGPSSWRRAATVMLAAGWTHSSPAGFRLLLLQRSQNQRFIPGAHVFPGGVLDAADSSPDWVRLFAPRHTPPRFGLGPEPPRQPPFPGLSHGDADPAALPDDVALRICAIRETFEEAGVLLLRPRDADPASQEPSQALSPPAGLAEWRSRVRSDPRCFLQLCAHLDCTPDIWALHDWGGWLTPYGRITRRFDTTFLLCCLRDTPRVEPDLAEVVGYQWLSPSEATECFLSKEIWLAPPQFYEIRRLDNFASLSALYRFCSDRPLEGGEKWLPIILLTSDGTIHLLPGDELYVKDSDFLEKNMSTDKKTEEIVKEGKVLNRVVIHSPYVYEIYMTLPSENKHVYPRNYVVNKRCTAHL
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).  Mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters and at low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates (By similarity).  Highest activity seen with medium-chain acyl-CoA esters and higher rates of activity seen with the unsaturated acyl-CoA esters compared with the saturated esters (By similarity).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
Acyl-coenzyme A diphosphatase NUDT19, Androgen-regulated protein RP2, Nucleoside diphosphate-linked moiety X motif 19, Nudix motif 19, Testosterone-regulated RP2 protein, RP2p.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: FOLD_BURVG
Sequence: MTALLIDGNALSKTLRAQAAERAAALTARGHQPGLAVILVGANPASEVYVRNKIKACEDNGFFSLKDAYPDTLSEADLLARIDELNRDPKIHGILVQLPLPAHIDSHKVIEAIAPEKDVDGFHVANAGALMTGKPLFRPCTPYGVMKMFEAHDIPLQGANAVVIGRSNIVGKPMAMLLLEAGATVTICHSKTRDLAAHTRQADIVVAAVGKRNILTADMVKPGATVIDVGMNRDDAGKLCGDVDFAGVKDVAGHITPVPGGVGPMTITMLLINTIEAAERAATA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PGK_WOLTR
Sequence: MMNIPNIENCDLHGKAVLLRVDFNIPIKNGKVHDATRVLRSLPTIRHLVNAGAKVIIISHFGRPRAKDNNLSLKNVVKTLSQLLNKEVKFVDDCIGKKVQKVVNAIAIRDVILLENLRFYKEEEQNDANFAKQLASLADVYVNDAFSCSHRAHASISRITEFLPSYAGFCLQDELRYLEKAVSFEAKPITAIVGGAKISTKIKMLIRLAEKVDYLVLGGAIANNFLLFNKVNIGKSFFQNGVDSLLHDVVKIADKNNCKIVIPEDVLIAVNSDYSTCILRKTESVLDNDVILDIGPQTLSTISSIVASSKALLWNGPIGVFEHSAFANGTIEVMKVVSDSTHKGKLTSVIGGGDSLSAINAAGLTDKDFTYVSTGGGAFLSWLSGDKMPGIAALQSMLN
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSH8_ARATH
Sequence: MAASSACLLGNGLSVYTTKQRFQKLGLDRTSKVTVVKASLDEKKHEGRRGFFKLLLGNAAAGVGLLASGNANADEQGQGVSSSRMSYSRFLEYLDKGRVEKVDLYENGTIAIVEAVSPELGNRIQRVRVQLPGLSQELLQKLRAKNIDFAAHNAQEDQGSPILNLIGNLAFPVILIGGLFLLSRRSSGGMGGPGGPGFPLQIGQSKAKFQMEPNTGVTFDDVAGVDEAKQDFMEVVEFLKKPERFTAVGARIPKGVLLVGPPGTGKTLLAKAIAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFKKAKENAPCIVFVDEIDAVGRQRGTGIGGGNDEREQTLNQLLTEMDGFEGNTGVIVVAATNRADILDSALLRPGRFDRQVSVDVPDVKGRTDILKVHSGNKKFESGVSLEVIAMRTPGFSGADLANLLNEAAILAGRRGKTAISSKEIDDSIDRIVAGMEGTVMTDGKSKSLVAYHEVGHAICGTLTPGHDAVQKVTLIPRGQARGLTWFIPSDDPTLISKQQLFARIVGGLGGRAAEEVIFGESEVTTGAVSDLQQITGLAKQMVTTFGMSEIGPWSLMDSSEQSDVIMRMMARNSMSEKLANDIDTAVKTLSDKAYEIALSQIRNNREAMDKIVEILLEKETMSGDEFRAILSEFTEIPPENRVASSTSTSTPTPASV
What is the function of this protein?
Part of a complex that function as an ATP-dependent zinc metallopeptidase.  Involved in the thylakoid formation and in the removal of damaged D1 in the photosystem II, preventing cell death under high-intensity light conditions.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FTSH 8, chloroplastic, AtFTSH8.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein; Stromal side.
Protein: FRIH_TREBE
Sequence: MESQVRQNFHKDCEAAINRQINLELYASYSYLSMAYYFDRDDVALPGFAHFFKQQSEEEREHAEKLLKFQNQRGGRIFLQDVKKPDRDEWGSGLDALECALQLEKNVNQSLLDLHKVCSEHNDPHMCDFLETHYLDEQVKSIKELGDWVTNLRRLGAPQNGMAEYLFDKHTLGK
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.  Also plays a role in delivery of iron to cells.  Mediates iron uptake in capsule cells of the developing kidney (By similarity).
What are the official names of this protein?
Ferritin, heavy subunit, Ferritin H.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: SYN_SYMTH
Sequence: MKWVTVDRLPQYEGQTVELRGWVQNYRSSGKIQFIIFRDGTGVCQAVLFIKDVPPEVFEAGKRLTQESSIIIRGSVRKDDRAPGGYEIGVQDLEIVQIAEEYPITKKEHGTEFLMDHRHLWIRSNRQVAILRIRNEITMAIHQFLQENGFVLTESPILMGTAAEGGATLFETTYVNDEPAYLSQSGQLHVEATAMALGRVYTFGPTFRAEKSKTRRHLIEFWMVEPEAAYFTHEDNMRLQEEMVTYVVRRVLERRSKELQLIGRDTTLLEKVEPPFPRITYTEAVEMLKKLHKPGDEWEPIEWGEDFGAPHETVLTQQFEKPVFVEKFPVKVKAFYMQPDPENPDVVLGADLLAPEGYGEIIGGSQRIHDPELLKRRFEEHGLDMNTYGWYYDLRRFGSVPHSGFGLGIERTVAWICGLEHVRETIPFPRLLNRLHP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_CHRVO
Sequence: MALLNILHYPDERLHTVAKPVEVFDAALQQQIDDMFETMYEAKGIGLAATQVDYHRRLVVMDISEERDERRVFINPEIVEKDGETVYEEGCLSVPGIYDKVTRAERVKVKAQDRDGKPFELEADGLLAICIQHELDHLNGVVFVERLSQMKQQRIKTKLKKREKQNM
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: WT1A_XENLA
Sequence: MGSDVRDMNLLPPVSSLSGNSSCNMPVSSSAQWAPVLDFPPGAPYSSLTPHSFIKQEPTWNPDPHEDQCLSAFTVHFSGQFTGTAGACRYGPFGAPTPSQATTGQARMFSNAPYLSNCLDNQQGMRNQGYSAVAFDGTPSYGHTPSHHTSQFTNHSFKHEDPLSQQTSLGEQQYSVPPPVYGCHTPTDTCTGSQALLLRTPYNSDNLYPMTSQLDCMTWNQMNLGSSLKSHGTSYENDSHSSPMLYNCGGQYRIHTHGVFRGIQDVRRVPGVTPAIVRSTEANEKRPFMCAYPGCNKRYFKLSHLQMHSRKHTGEKPYQCDFKDCERRFSRSDQLKRHQRRHTGIKPFQCKTCQRKFSRSDHLKTHTRTHTGKTSEKPFSCRWPSCQKKFARSDELVRHHNMHQRNMTKLQLAL
What is the function of this protein?
Transcription factor required for development of the vascular component of the pronephric kidney, the glomus; may repress tubule-specific gene expression in the portion of the pronephros fated to form the glomus.  Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3' (By similarity).  Inhibits Wnt-signaling during embryonic development.  Function may be isoform-specific: the isoform containing the KTS motif is less effective in inhibiting wnt signaling.
What are the official names of this protein?
Wilms tumor protein homolog A, XWT1a, xWT1.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus speckle. Note=Shuttles between nucleus and cytoplasm.
Protein: COAX_HELHP
Sequence: MLLCDIGNTFLHFYHKGRIWKEKPYALTKKKENLPIYYISVNERFERCLLASHPHCVNVNEHIELQTQYVGLGVDRKAACRAIDNGVIIDAGSAITADVMQEGVHIGGYIMPGLEAYRRMYSDISPVLNREIEPGVNLSILPQNTADAISFGVLKSVILMIKNTSRTKKLYFTGGDGKFFARFFENAIYDNTLVFKGMQKVLEKQI
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_BRUME
Sequence: MSDDTTQIEPAMAQETSPRANTRKVFVKTYGCQMNVYDSQRMADSLAAEGYVATDTPDDADLVLLNTCHIREKASEKLYSALGRLRKMKDARAADGKELTIGVAGCVAQAEGQEILRRAPNVDLVIGPQTYHRLPNALARVRGGEKVVETDYAIEDKFEHLPAPRREETRKRGVSAFLTVQEGCDKFCTFCVVPYTRGSEVSRSVKQIVAEAERLADSGVRELTLLGQNVNAWHGEGEDGREWGLGELLFRLARIPGIAHLRYTTSHPRDMDDSLIAAHRDLRQLMPYLHLPVQSGSDRILKAMNRRHKADEYLRLIERIRNVRPDMALSGDFIVGFPGETDQDFEDTMQLVRDVNYAQAYSFKYSPRPGTPGADLDDHVEEAVKDERLQRLQALLSAQQYAFQDSMIGRKMDVLLEKPGREAGQMVGRSPWLLPVIIDDNKDRVGDIIHVKIVSTGTNSLIAQKLA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RACD_ENTFU
Sequence: MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHATVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPILHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINYLIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQSILADRTIERALAERSEALDTASEK
What is the function of this protein?
Aspartate racemase that provides the D-aspartate required by the D-aspartate ligase to be added onto the lysine residue in the peptidoglycan precursor UDP-MurNAc-pentapeptide.
What are the official names of this protein?
Aspartate racemase, Rac(fm).
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: YRHP_BACSU
Sequence: MHSLLAYIPIAAMMVIIPGADTMLVMKNTLRYGPKAGRYNILGLATGLSFWTVIAILGLSVVIAKSVILFTTIKYLGAAYLIYLGVKSFFAKSMFSLDDMQSQAKNMASSPKRYYKTSFMQGSLSNILNPKTVLVYVTIMPQFINLNGNINQQLIILASILTLLAVLWFLFLVYIIDYAKKWMKNSKFQKVFQKITGIILVGFGIKTGLS
What are the official names of this protein?
Uncharacterized membrane protein YrhP.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PANB_CAMJR
Sequence: MRKSILSFLEKKGKNEKITMVSAYDYHSAKILDNCDIDIILVGDSLAMTVLGMQDTLSVTMDEMLIFTKAVSRGAKKSFVLADMPFMSYQSSDRDAILNASRFIKESHANGVKVEGGIEIASKIKLISQSGIPVVAHLGLTPQAVNMLGGYRVQGKDLQSAQKIIDDAKAVQDAGACMLVLECVPVKLAQKISSILEIPTIGIGSGKYCDGQVLVYHDLLGLNKDFKAKFVKHFDKIDPQVGVEKYRDEVKSGIFPSEEHSFDYLDDELLDKLY
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFN1_RAT
Sequence: MAETVSPLKHFVLAKKAITAIFGQLLEFVTEGSHFVEATYRNPELDRIATEDDLVEIQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPLEARNRIFFVSAKEVLNSRMNKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTMDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGRNLADRCTSEVNASILQSQQEIIENLKPLLPAGIQNKLHTLIPCKKFDLSYDLNCHKLCSDFQEDIVFRFSLGWSSLVHRFLGSTNAQRVLLGLSEPIFQVPRSLASTPTAPSNPAAPDNAAQEELMITLITGLASLTSRTSMGIIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVKFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSKLLRNKAVQLERELENFSKQFLHPSSGES
What is the function of this protein?
Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion (PubMed:14561718, PubMed:12589796).  Membrane clustering requires GTPase activity.  It may involve a major rearrangement of the coiled coil domains (By similarity).  Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events (PubMed:14561718).  Overexpression induces the formation of mitochondrial networks (in vitro) (PubMed:14561718).  Has low GTPase activity (By similarity).
What are the official names of this protein?
Mitofusin-1, Mitochondrial transmembrane GTPase FZO1B, Transmembrane GTPase MFN1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. Mitofusin subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: RS4_AYWBP
Sequence: MSRYTGSLWKVSRRLNYSVSETGKELHKRAYGPGQHGQKKVKLSDYGFQLQEKQKLRFTYGVSEKQFRKTFDNASKLKGIHGEMFLVLLESRLDNVVYRLGFAKTRAQARQLVNHGHILVDGKKVDIASYRLKPGQTVTLREKSKNLNIVQEALNSKFVRADYVSLDKELVGKYVRYPQRNEFLPDINEQLIVEYYNR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: DHAS_SYNY3
Sequence: MPSPIRVAILGATGAVGTELLELLASRNFPLAELKLLASPRSAGKTLEFQGEKLPIQAVDGSAFKGCDLVLASAGGSTSKRWAEEITKAGAVMVDNSSAFRMVPEVPLVVPEINPEAAQNHQGIIANPNCTTILMGVAIYPLHQLQPIKRIVVATYQSASGAGAMAMEEVKHQSRDILEGKIPQAEILPYPLAFNLFPHNSPITANHYCEEEMKMVQETRKIFAAEDIRITATCVRVPVLRAHSEAVNLEFATPFPVELAKTAIAKAPGVKLVEDWQKNYFPMPMDATGQDDVLVGRIRQDISHPNGLDLWLCGDQIRKGAALNAVQIAELLVERGWL
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: ACSA_RHIE6
Sequence: MSDKIHPVPKQVKAQALIDKEKYLKWYEESVENPDKFWGKHGKRIDWFKPYTKVKNTSFTGKVSIKWFEDGQTNVSYNCIDRHLKTNGDQVAIIWEGDNPYIDKKITYNELYEHVCRMANVLKKHGVKKGDRVTIYMPMIPEAAYAMLACARIGAVHSVVFGGFSPEALAGRIVDCESTFVITCDEGLRGGKPVPLKDNTDTAIHIAARQHVHVSKVLVVRRTGGKTGWAPGRDLWYHQEVATVKAECPPVKMKAEDPLFILYTSGSTGKPKGVLHTTGGYLVYASMTHEYVFDYHHGDIYWCTADVGWVTGHSYIVYGPLANCATTLMFEGVPNFPDQGRFWEVIDKHKVNIFYTAPTAIRSLMGAGDDFVTRSSRSSLRLLGTVGEPINPEAWEWYYNVVGDKRCPVIDTWWQTETGGHMITPLPGAIDLKPGSATVPFFGVKPQLVDNEGKVLEGAADGNLCITDSWPGQMRTVYGDHERFIQTYFSTYKGKYFTGDGCRRDEDGYYWITGRVDDVLNVSGHRLGTAEVESALVSHNLVSEAAVVGYPHAIKGQGIYCYVTLMAGHEGTDTLRQELVKHVRAEIGPIASPDKIQFAPGLPKTRSGKIMRRILRKIAEDDFGALGDTSTLADPAVVDDLIANRQNKATA
What is the function of this protein?
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways.  AcsA undergoes a two-step reaction.  In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate.  In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
What are the official names of this protein?
Acetyl-coenzyme A synthetase, AcCoA synthetase, Acs, Acetate--CoA ligase, Acyl-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.