PharMolix/UniProtQA huggingface dataset:
Protein: Y928_ENTFA
Sequence: MSLLIALVPMIAWGSIGLVSGKIGGSANQQTLGMTIGALLFSIVVFFVIQPTLTTATLIVGFISGLFWSLGQNQQFHSMKYMGVSVGLPISTGMQLVVNTVAGAVFFHEWTKTKDFVVGFIALAFLVFGVYLTARQDDDSQPKTSNSMLDFNKGIRALIFSTVGYGVYTIIINATGLDPWGIILPQSIGMLVGASFFAFKKVKVDRFVWMNMTTGLLWGLGNICMLLTMREIGLAISFSLSQMGIIISTLGGIFLLGERKSKKEMFYVIFGCIFVILGGILLGYMKA
What are the official names of this protein?
Putative sugar uptake protein EF_0928.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RODA_ECOLI
Sequence: MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIGMMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRWLDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTGIALVLIFMPTLLVAAQPDLGTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPESDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVGILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGVPLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell wall elongation (PubMed:27643381).  Also required for the maintenance of the rod cell shape (PubMed:2644207).  Functions probably in conjunction with the penicillin-binding protein 2 (mrdA) (PubMed:2644207, PubMed:27643381).
What are the official names of this protein?
Peptidoglycan glycosyltransferase MrdB, PGT, Cell elongation protein RodA, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase, Rod shape-determining protein.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. MrdB/RodA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: THSA_SULAC
Sequence: MAGPVLLFKEGTSRSSGRDALRNNILAAVTLAEMLKSSLGPRGLDKMLIDSFGDVTITNDGATIVKEMEIQHPAAKLLVEAAKAQDAEVGDGTTSAVVLAGLLLDKAEELLEQNVHPTIIIDGYKKALTKALEIIDQLSLKIDVNDLSSPTAKAQLKKIVSTTMSSKFIAGGAEEIDKIIDLVIDAITIVAEKRPDGTYNVPLDLIKIDKKKGGSIEDSILVHGLVLDKEVVHAGMPRRVEKAKIAVLDAALEVEKPEISAKISITSPEQIKSFLDEEARYLKEMVDKLASIGANVVICQKGIDDVAQHFLAKKGILAVRRVKRSDIEKLEKALGARIISSIKDATPEDLGYAELVEERRIGNDKMVFIEGAKNPRAVNILLRGSNDMALDEAERSLNDALHSLRNVLMKPMIVAGGGAVESELALRLREYARSVGGKEQLAIEKFAEALEEIPMILAETAGMEPIQALMDLRARHAKGLVNSGIDAVNGKIADDMMKINVIEPVRVKSQVLKSAVEAATAILKIDDLVAASALKTEKGKKEGGEGAGAETPGAPSLE
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit alpha, Chaperonin subunit alpha, Thermophilic factor 55 alpha, TF55-alpha, Thermosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: TRPD_SHEDO
Sequence: MLTQVSATQADSNQASQASQALLDTLYQGHALTRSQSETLFASIVAGDMDPVAMAGMLVALKMRGETTAEITGAADALRSAAKPFPRSADSISTGVLDIVGTGGDGFNTINISTTAAFVAAAAGAKVAKHGNRGVSSKSGSSDLLTHCGIGLTMSPKAASACLDTLGLSFLFAPHYHEGVRHAVPVRQALKTRTIFNILGPLINPAKPEFMLLGVYSPKLLAPIVNVLNALGVKRAMVVYGSGLDEVALHGDTQVAELNNGDIRFYHLTPEELGVERADLNLLTGGEPSDNALITKAILQGKGEAAQRDAVAINAGCALYISGISDSVQAGTKLALATLKTGKAFDVLTQLAEASQTEAQG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CLDN2_MOUSE
Sequence: MGVKKSLQTGGNLLNLLSSILTVLSTTTNYWTRQQGGHSGLWQECTHGKCSNIPCQNTVAVSAACMVLAATFSIVALGIGIRIQCREAESRRSQNTIVLLFLSGLLLLIALAVYTSKNAWKPEVFFSWSYFFGWLALPFLFIAGFCFLLADMILQSTEAISGFPVCL
What are the official names of this protein?
Claudin domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NRAM_I74A2
Sequence: MNPNQKIITIGSVSLGLVVLNILLHIVSITITVLVLPGNGNNGSCNETVIREYNETVRIEKVTQWHNTNVIEYIERPESDHFMNNTEPLCDVKGFAPFSKDNGIRIGSRGHVFVIREPFVSCSPTECRTFFLTQGSLLNDKHSNGTVKDRSPYRTLMSVEIGQSPNVYQARFEAVAWSATACHDGKKWMTIGVTGPDAKAVAVVHYGGIPTDVIQSWAGDISRTQESSCTCIQGECYWVMTDGPANRQAQYRAFKAKQGKIIGQTEISFNGGHIEECSCYPNEGKVECVCRDNWTGTNRPVLVISSDLSYRVGYLCAGLPSDTPRGEDSQFTGSCTSPMGNQGYGVKGFGFRQGNDVWMGRTISRTSRSGFEVLKVRNGWIQNSKDQIKRQVVVDNLNWSGYSGSFTLPVELTKRSCLVPCFWVEMIRGKPEETTIWTSSSSIVMCGVDHEIADWSWHDGAILPFDIDKM
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: GYRA_GRABC
Sequence: MSDHTNPPSAPPDDDPNGGSLLMPVTLEEEMSRSYLDYAMSVIVSRALPDARDGLKPVHRRILYGMQESGYTADKPYRKSARINGDVMGKYHPHGDAAIYDALVRLAQPFSLRVPLIDGQGNFGSMDGDPAAAPRYTEARLARSASFLLNDIDRDTVDFQPNYDDSEMEPRVLPASYPNLLVNGADGIAVGMATKIPTHNPTEVIDATLAMIDNPDITLDELMTVIPGPDFPTGGLILGRSGIRSAFETGKGSITVRARTDFEEVRGGRQAIVISEIPYQVNKATLQERMAELVRAKQIEGISDIRDESDRSGVRVVIELKRDATPDVVLNHLFRFTQLQISYGINMLALDGGQPRLMGLRDVLSTFIRFREDVILRRARFELNKARDRAHLLVGLAIAVANIDEVIRLIRQSPDSTSARIALMERDWPAADVAPLLTLIDDGGNVLTEAQTVRLTEVQARGILELRLQRLTGLERDKIHNEMQEVAARIGELLEIIGSHIRRMEVMREELAVIRAELNSPRRSEINDSLADQDDESLIEPGQMVVTITRDGFIKRTPLDVFRQQHRGGRGRAAASMRGDDIVTRSFNAHTHQWVLFFSSGGKAYRQKVWRLPEAGPTAKGRALVNLLPELGSDGITAVLPLPQDESLWEGLHLVFATASGGIRRNRLSDFKNVRASGLIAMKLDEGDRLIGVATCREGDDIMLASRLGRCIRFQANEDTLRVFAGRESSGVRGMKLAQGDEVISLSVLRHVEATPEERAAYLRYASARRRSAAGEEDQIDAEVMEADDSEVTVDDTALSPERIAGLEEAEEFLLTVTIAGFGKRSSAYDYRVSGRGGQGIANINLAPRNGRAVAATFPVRPGDDVMLVTDAGRLIRVPADQVRITGRSTMGVTLFRVDKDEVVTSVFPVLETESVDDNGDDADSVAPAAPDGQVTDSDD
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2570_BURO0
Sequence: MDARLLEIIVCPICKGPLHYDRAAQELICNADKLAYPIRDGIPVMLVDEARQTVEGTPVDPAGR
What are the official names of this protein?
UPF0434 protein Bcenmc03_2570.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: ARY2_RABIT
Sequence: MDIEAYYQRIGYKNPRNKLDLESLTDIFQHQIRTVPYENLSIHCGESMELDLEAIFDQIVRRNRGGWCLQVNYLLYWALTTTGFETTMLGGFVYGSNNDKYSTGMIHLIVQVTINGRNYIVDAGFGRSYQMWQPVELISGKDQPQVPSIFRLREEGETWYLDQIRRQQHVPDQEFLNSELLEKKIYQKLYCFTLQPRTIEEFESANTYLQESPSSVFLDKSICSLQTPEGVHCLVGLTLTSRTYNYKENTDLVEFKVLTEEEVEGVLKTIFNISLGKKLVSKNGHLSFTI
What are the official names of this protein?
Arylamine N-acetyltransferase 2, Arylamide acetylase 2, N-acetyltransferase type 2, NAT-2, Polymorphic arylamine N-acetyltransferase, PNAT.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_STAAW
Sequence: MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGDLSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDEEESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: ICP47_CHV16
Sequence: MSSLYLAEVDAFLQSPRTRHRTCADLRRELDAYADEERREAAKAIAHPDRPLLAPPSAPPDRSRPAPRGTAHPPAASP
What is the function of this protein?
Plays a role in the inhibition of host immune response.  Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules.  Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
What are the official names of this protein?
ICP47 protein, Immediate-early protein IE12, Immediate-early-5, Infected cell protein 47, US12 protein, Vmw12.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae US12 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: Y1472_METJA
Sequence: MYFSQNAIILVMLMFVISAVFYATIDYKTKEVEDEIKIKEVSLYEKNLINTIDRNIDKIVEDAFVNASYKIMKERKFFTASSEAVAYITSYIKNETKESLNNVNYGYSNISYNISSVKISPTYDPLVVHLYCEIDIKYSKKLNNGELIALKPIVINRDIKLSRIPDPYVYLNKFYYTWGYEKKINIYNFPNDNYNRTFCIILNSSNFNYSEMHNPQSPTELRVIGWDSVSNKIILLPYWVQTWREGNNDVSVIWVRANKNEIYNYNNGQGYIYILYNSTTPVDRQDPEHTFIFFDDFNYFNPDKWDSVGYFIINNSKITVIAGAGSSVYTKQTYGTRYELIFRANFTPSHAQTIGFFTQLSDNDGVGWDMYDWTGNNPELYMRVGYSGSDIGDYVPNSNKYLNKFYIYDLKRISTTDLNFTIFNDTLDIEYSNSFTNGNKGNNYPISITALINLNTNVTVDWIFLKDINDITTTVPPIGVDEYPNLDYKEEKPKTFTGTIYYGEPGKYILVYNSTYSIIGLYTNKTDYWLYPNMPGYKPLIEEN
What are the official names of this protein?
Uncharacterized protein MJ1472.
Protein: GLMM_CLOK5
Sequence: MHRMFGTDGVRGIANKELTPELAYKLGKAGAYVLTGRCHKPKILVGMDTRISGDMLENALVSGILSIGAEAICVGIVPTPAVAYLTRKYNADAGVVISASHNPVEYNGIKFFNGKGYKLSDELEDKIQYVIESNFKDVSIPIGSKVGRKIMETGEARKAYIEFAKSTIDTDLKDLKVVLDCANGASYVTSVKAFQELGAKVKVINNEPDGININHNCGSTHPENLMKTVVEEGYDMGLAFDGDADRCLAIDEKGNLINGDFIMAIIAKHLKNQGKLYKNVVVSTVMSNVGFDIALKEEGINTIKTQVGDRYVLEEMRKEGYKLGGEQSGHIIMLDYNTTGDGLITALQIACIVKKSGRKLSDIASMMKNLPQTLVNAKVPDDKKKIYMEDEEIVLKIKEIERKLHGCGRVLIRPSGTEPLVRVMLEGEEQGEIDKMAHNLAELIEVKLN
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CLIC5_BOVIN
Sequence: MNDENYSTTIYNRVQTERVYEDSDPAENGGPLYDEVHEDVRREDNLYVNELENQEYDSVAVYPVGRQGRTSASLQPETGEYVLPDEPYSKAQDPHPGEPTADEDISLEELLSPTKDHQSDSEEPQASDPEEPQASDPEEPQGPDPEEPQENGNEMEADLPSPSSFTIQNSRAFSTREISPTSYSADDVSEGNESASASPEINLFVKAGIDGESIGNCPFSQRLFMILWLKGVVFNVTTVDLKRKPADLHNLAPGTHPPFLTFNGDVKTDVNKIEEFLEETLTPEKYPRLAAKHRESNTAGIDIFVKFSAYIKNTKQQSNAALERGLTKALKKLDDYLNTPLPEEIDADTRGDDEKGSRRKFLDGDELTLADCNLLPKLHVVKIVAKKYRNYDFPAEMTGLWRYLKNAYARDEFTNTCAADSEIELAYADVAKRLSRS
What is the function of this protein?
Required for normal hearing.  It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti.  Can insert into membranes and form poorly selective ion channels that may also transport chloride ions.  May play a role in the regulation of transepithelial ion absorption and secretion.  Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture.  Plays a role in formation of the lens suture in the eye, which is important for normal optical properties of the lens.
What are the official names of this protein?
Chloride intracellular channel protein 5, Chlorine channel protein p64.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Membrane; Single-pass membrane protein. Apical cell membrane; Single-pass membrane protein. Cytoplasm. Note=Colocalizes with AKAP9 at the Golgi apparatus as well as, to a lesser extent, the centrosome (By similarity). Associates with the cortical actin cytoskeleton (By similarity). Localizes to the apical region of cochlear hair cells, at the base of the actin-rich hair bundle (By similarity). Colocalizes with podocalyxin at the apical cell membrane in renal glomeruli (By similarity). May localize to the centrosome in lens epithelial cells (By similarity). Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain (By similarity).
Protein: WZYE_YERPN
Sequence: MTLGQFGGLFCIYLIAVIFILTLTYQEFRRVKFNFNVLFSMLYLLTFYFGFPLTCMLVFQFGVAVVPVEYLLYAMLSATAFYGIYYVTYKTRLRQPRSQPRTPIFTMNRVETNLTWVLLALVAVGTVGIFFMQNGFLLFKLDSYSKIFSSDVSGVALKRFFYFFIPAMLVVYFLKQDRRAWFFFLASTVAFGILTYVIVGGTRANIIIAFSLFLFIGIVRGWITLWMLAAAGVFGIVGMFWLALKRYGLDVNGAEAFYTFLYLTRDTFSPWENLGLLLQNYDKIDFQGLAPIVRDFYVFIPSALWPERPDLVLNTANYFTWDVLDNHSGLAISPTLIGSLVVMGGVLFIPLGAIVVGLIIKWFDWLYEQGKAESNRYKAAILQSFCFGAVFNIIVLAREGLDSFVSRVVFFCVIFGACLVLAKLLYWLFDTAGLIKRQGIKSNRLSTPNAGNQL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: URM1_CAPHI
Sequence: MAAPLSVEVEFGGGAELLFDGVKKHQVTLPGQEEPWDIRSLLVWIKKNLLKERPELFIQGDSVRPGILVLVNDADWELLGELDYQLQDQDSVLFISTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECHM_HUMAN
Sequence: MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
What is the function of this protein?
Converts unsaturated trans-2-enoyl-CoA species ((2E)-enoyl-CoA) to the corresponding (3S)-3hydroxyacyl-CoA species through addition of a water molecule to the double bond (PubMed:25125611, PubMed:26251176).  Catalyzes the hydration of medium- and short-chained fatty enoyl-CoA thioesters from 4 carbons long (C4) up to C16 (PubMed:26251176).  Has high substrate specificity for crotonyl-CoA ((2E)-butenoyl-CoA) and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA (3-methyl-(2E)-butenoyl-CoA) and methacrylyl-CoA ((2E)-2-methylpropenoyl-CoA) (PubMed:26251176).  Can bind tiglyl-CoA (2-methylcrotonoyl-CoA), but hydrates only a small amount of this substrate (PubMed:26251176).  Plays a key role in the beta-oxidation spiral of short- and medium-chain fatty acid oxidation (PubMed:25125611, PubMed:26251176).  At a lower rate than the hydratase reaction, catalyzes the isomerase reaction of trans-3-enoyl-CoA species (such as (3E)-hexenoyl-CoA) to trans-2-enoyl-CoA species (such as (2E)-hexenoyl-CoA), which are subsequently hydrated to 3(S)-3-hydroxyacyl-CoA species (such as (3S)-hydroxyhexanoyl-CoA) (By similarity).
What are the official names of this protein?
Enoyl-CoA hydratase, mitochondrial, mECH, mECH1, Enoyl-CoA hydratase 1, ECHS1, Short-chain enoyl-CoA hydratase, SCEH.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CNRP1_HUMAN
Sequence: MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYDTEGVTPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL
What is the function of this protein?
Does not suppress cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.
What are the official names of this protein?
CB1 cannabinoid receptor-interacting protein 1, CRIP-1.
What is the protein family that this protein belongs to?
Belongs to the CNRIP family.
Protein: ACM3_BOVIN
Sequence: MTLHNNNTTSPLFPNISSSWIHGPSDTGLPPGTVTHFGSYNISRAAGNLSSPNGTTSDPLGGHTIWQVVFIAFLTGVLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFILWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQSMKRSARRKYGRCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGSVGLERKPSKLQTQQSMDDGGSFQKSFSKLPIQLESAVDTAKASDVNSSVGKTTATLPLSFKEATLAKRFALKTRSQITKRKRMSLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRNTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
What is the function of this protein?
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.  Primary transducing effect is Pi turnover.
What are the official names of this protein?
Muscarinic acetylcholine receptor M3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM3 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Colocalizes with TMEM147 in the endoplasmic reticulum (ER) membrane. TMEM147 impairs its trafficking to the cell membrane leading to its retention in the ER membrane.
Protein: MYG_PUSSI
Sequence: MGLSDGEWHLVLNVWGKWETDLAGHGQEVLIRLFKSHPETLEKFDKFKHLKSEDDMRRSFDLRKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSKHPAEFGADAQAAMKKALELFRNDIAAKIKELGFHG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: AROA_KLEP3
Sequence: MESLTLQPIARVEGTVNLPGSKSVSNRALLLAALARGTTVLTNLLDSDDVRHMLNALSALGVQYTLSADRTRCEVTGNGGPLRAAAALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAQIDYLEQENYPPLRLRGGFQGGNVEVDGSVSSQFLTALLMTAPLAPQDTVIAIKGDLVSKPYIDITLHLMKTFGVEVDNQSYQRFVVRGKQQYQSPGDYLVEGDASSASYFLAAGAIKGGTVKVTGIGRGSVQGDIRFADVLEKMGATVTWGDDFIACTRGELKAIDMDMNHIPDAAMTIATAALFAQGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGEDYIRITPPAKLKYAEIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISTLA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOK_SHEWM
Sequence: MIDTTWVIILSFLLFAIGTFGLLSRRNLLFILLSLEIMLNGIILLFIAASNLHGNNDGQIMYLLVLTLAASEVAVGLALVVQIYKQQQNLDVDTLTKLRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLGK_BORBU
Sequence: MDSTFSGIEIGKRSLFAHKDAMNTVGHNLSNATKPGYSRQRVTMKTEIPLYAPQLNRAKKQGQLGQGIVVQSIDRVKDELLNTRIIEESHRLGYWTSQDKFISILEDVYNEPEDQSIRKRLNDFWESWHDLANQPQGLAERKIILERGKSFCEGIRNRFHSLERIYIMANDEIKITTDEANNYIRNIANLNKQISKSQAMKDNPNDLMDARDLMVEKLGNIISVSIENKQDPNEFLIHAEGRHLVQGSIANEFKLEATNGPTRTRWNILWANNDKAYLKTGKLGSLLNIRDEEIKNEINELNNIAANIIEIVNEIHEAGRGMDKKNGRSFFSQELKLTDDRGRYDTNGNGQFDSVHIFKINSTNEIFPEEKLGFYGTLKFEATNSNEIVEIPYNAPDTVQDVINRINNSNAQVTARINSEGKLEIKAVKEQEDENITFKIKHIEDSGSFLTKYTGILNASGPEGAYDYKNIDTTDKLAPKSTYSISPLKNPAAWIKVADIIDSDPSKIASGIKNPTNEISIGDNQAALRISSFGNSQIMIGKNLTLNDYFANTASNIAIKGQISEITKESQSQILKDLTDLRMSISGVNKDEELANMIEFQQAFIAASKFITVSVELIDTVINKMGV
What are the official names of this protein?
Flagellar hook-associated protein 1, HAP1.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.