PharMolix/UniProtQA huggingface dataset:
Protein: TATB_DICNV
Sequence: MFEIGFWELVLVAIIGIVVVGPKRLPEVVRTLGLLLRKMRRTISSVRADIERELDLEEMRKLMSDVDEPLKKHVDQLNQSIWQAEYDLRQGGKNLLKMIDEPPYQEPPPAAHSVQTDAEAYRDTGIEPADKSSSPEHHHDDAAR
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DER_STAEQ
Sequence: MTKPIVAIVGKPNVGKSTIFNRVVGERISIVEDTPGVTRDRIYSSGEWLTHEFNIIDTGGIEIGDAPFQTQIRAQAEIAIEEADVIIFMVNVREGLTQSDEMVAQMLYKSKKPVVLAVNKVDNLEMRNDIYDFYSLGFGDPYPISGSHGLGLGDLLDAVVENFNKESEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEERVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSEVVLVVIDAEQGIIEQDKRVAGYAHEEGKAIVIVVNKWDTVEKDSKTMKKFTDDVRNEFQFLDYAQIAFVSAKEGLRLKTLFPYINQASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYTTQVAIEPPTFVVFVNDVELMHFSYRRYLENQIRNAFGFEGTPIHIIPRKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: EFTU_LISIN
Sequence: MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLAKKGFADAQAYDQIDGAPEERERGITISTAHVEYQTDNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPYIVVFMNKCDMVDDEELLELVEMEIRDLLTEYEFPGDDIPVIKGSALKALQGEADWEAKIDELMEAVDSYIPTPERDTDKPFMMPVEDVFSITGRGTVATGRVERGQVKVGDEVEVIGIEEESKKVVVTGVEMFRKLLDYAEAGDNIGALLRGVAREDIQRGQVLAKPGSITPHTNFKAETYVLTKEEGGRHTPFFNNYRPQFYFRTTDVTGIVTLPEGTEMVMPGDNIELAVELIAPIAIEDGTKFSIREGGRTVGAGVVSNISK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_FRAT1
Sequence: MDLNIKSLAGQEAGSLGVAEGVFAADYNEALIHQVVVAYMAGARQGTKAQKTRSEVSGGGAKPWRQKGTGRARAGTIRSPIFRKGGVTFAAKPKSYKQKVNRKMYSGAVKSILSELLRSGRMTIVEELKLETPKTREFKSVIDSLGVKDVLFVVGVEEFSENLYLSSRNLKNVAVCDSVEINPVSLVCFENVVLTKKAIKEIEEKLV
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GATA3_HUMAN
Sequence: MEVTADQPRWVSHHHPAVLNGQHPDTHHPGLSHSYMDAAQYPLPEEVDVLFNIDGQGNHVPPYYGNSVRATVQRYPPTHHGSQVCRPPLLHGSLPWLDGGKALGSHHTASPWNLSPFSKTSIHHGSPGPLSVYPPASSSSLSGGHASPHLFTFPPTPPKDVSPDPSLSTPGSAGSARQDEKECLKYQVPLPDSMKLESSHSRGSMTALGGASSSTHHPITTYPPYVPEYSSGLFPPSSLLGGSPTGFGCKSRPKARSSTGRECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRNRKMSSKSKKCKKVHDSLEDFPKNSSFNPAALSRHMSSLSHISPFSHSSHMLTTPTPMHPPSSLSFGPHHPSSMVTAMG
What is the function of this protein?
Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes.  Binds to the consensus sequence 5'-AGATAG-3'.  Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses.  Positively regulates ASB2 expression (By similarity).  Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33.  Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages.
What are the official names of this protein?
Trans-acting T-cell-specific transcription factor GATA-3, GATA-binding factor 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL19_PSEMY
Sequence: MTNKIIQMLEAEQMNKEIPTFAPGDTVVVQVKVKEGDRQRLQAFEGVVIAKRNRGLNSAFTVRKISSGVGVERTFQTYSPLVDSLSVKRRGDVRKAKLYYLRDLSGKAARIKEKLS
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: LV327_HUMAN
Sequence: MAWIPLLLPLLILCTVSVASYELTQPSSVSVSPGQTARITCSGDVLAKKYARWFQQKPGQAPVLVIYKDSERPSGIPERFSGSSSGTTVTLTISGAQVEDEADYYCYSAADNN
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda variable 3-27, Ig lambda chain V-IV region Kern.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: CD9_PIG
Sequence: MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQENNNSSFYTGVYILIGAGALMMVVGFLGCCGAVQESQCMLGLFFGFLLVIFAIEIAAAIWGYSHKDQVIKEVQDFYRDTYNKLKGKDDPQRETLKAIHYALDCCGLMGEVEQLLADICPQRDVLSSLPMKPCPEAIKEVFQNKFHIIGAVGIGIAVVMIFGMIFSMILCCAIRRSREMV
What is the function of this protein?
Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity).  Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity).  In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity).  In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity).  Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity).  Acts as a receptor for PSG17 (By similarity).  Involved in platelet activation and aggregation (By similarity).  Regulates paranodal junction formation (By similarity).  Involved in cell adhesion, cell motility and tumor metastasis (By similarity).
What are the official names of this protein?
CD9 antigen.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Secreted, extracellular exosome. Note=Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO.
Protein: PURR_SHISS
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLVGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: RHAM_SHIFL
Sequence: MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGVHNYAIYLDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UCRI_BRADU
Sequence: MTTASSADHPTRRDFLFVATGAAAAVGGAAALWPFISQMNPDASTIAAGAPIEVDLSPIAEGQDIKVFWRGKPIYISHRTKKQIDEARAVNVASLPDPQSDEARVKSGHEQWLVVIGICTHLGCIPIAHEGNYDGFFCPCHGSQYDSSGRIRQGPAPANLPVPPYQFVSDTKIQIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CECB_DROMA
Sequence: MNFNKIFVFMALILAISLGNTEAGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-B.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TGT_ACIF2
Sequence: MSIFQLLARDGAARRGTIRLPRGTVQTPAFMPVGTYGTVKAMSPEELKTLGAEIILGNTFHLFLRPGLEVISAVGGLHRMMHWDRPILTDSGGFQVFSLGALRKLTEAGVQFRAPTDGHMVFLGPEESMQIQAALGSDIAMVFDECTPHPASYEEARVSMELSLRWAARSHAAYAGPGELFGIVQGGMYADLRRRSLAGLQRLDFPGLAIGGLSVGESKVEMMQVLDDLMPHMPADRPRYLMGVGTPEDLVEGVRRGVDMFDCVMPTRNARNGWLFTRDGVLKLRNARYEKDVLPPDPACACYTCQNYSRAYLRHLQRSHEILGARLNTLHNLHYYQELMAGLREAIAAGRLDAYADDFYRRRRAGSLVGA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: KITH_MESFL
Sequence: MIPNRDTIEQKQLGWVELITGCMFAGKTEEFIKRLRRHAFAKRNVIAFKPVIDTRYAVNEVASHAGTLLPSIPVNSTAELKEKLEAKILEKKVDVVGIDEIQFFDEAIVDYIEELADRGIIVIVTGLDKDFRSQPFKNVDRILPLAEMVDKLTAICQKCGNFANRTQRIIDGKPADWNSPLILVDGNDSYEARCRNCYQIEKG
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_HELPJ
Sequence: MVTMKDLLECGVHFGHQTRRWNPKTKKFIFGVRKNIHIIDLQKTLRYFRYTYNIVRDASAQGKSIMFVGTKKQANETLKEFAESIQVPYVNYRWLGGMLTNFSTIRKSVRKLEIIEEMENSGQIDLLTKKEKLMILRKKEKLDKYLGGVRHMKKIPDMIFVIDVAKEKIAVAEARKLHIPIVAPLDTNCDPDLVDYPIPGNDDAIRSIRLFCKEMSEAILEGRELMQEEIVHADENSEEIEFVSNEEKEEMLAEIQKEITQGAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: COBT_ECOSM
Sequence: MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAIQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVLAAQAGANVYVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRHQAEKLLLDVICYTRELAKNGVTLFGVGELGMANTTPAAAIVSTITGRAPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPFLNMEMRLGEGSGAALAMPIIEAACAIYNNMGELAASNIVLPGNTTSDLNS
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: AUR11_RANRN
Sequence: GLFDIIKKIAESI
What is the function of this protein?
Antimicrobial peptide with activity against B. cereus, L. lactis, L. innocua and S. uberis (PubMed:10951191).  Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10951191).  Inhibits the formation of NO by neuronal nitric oxide synthase (nNOS) at micromolar concentrations (PubMed:11784303).  Acts by a non-competitive mechanism, probably by binding to calcium/calmodulin and as a consequence blocking calmodulin attachment to nNOS (By similarity).
What are the official names of this protein?
Aurein-1.1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FDHD_HAEI8
Sequence: MQCWIRQTINFFRKTKNTEKLTALLQQKEDILAVEMPVSLVYNGISHAVMMCSPNNLEDFALGFSITEGIIDKPEDIYGIDVVEVCNGIEVQIELSSRKFMALKEHRRNLTGRTGCGICGTEQLNQVYKTFPKLDCTFQFDLNLLDSCLIDLQKNQLLGCKTGATHACAFFDLYGNMLAIYEDVGRHVALDKLLGWHAKSGKPRGFILASSRASYEMVQKTVACGVEMLVTISAATDLAVTMAEKHNLTLIGFAREGKGNIYSGHQRLHN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_PASMU
Sequence: MKTFVAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVINAEKVAVTGNKESDKLYHWHTGYVGGIKQATFKEMIARRPEAVIEIAVKGMLPKGPLGRAMYRKLKVYAGSEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RIMP_STUS1
Sequence: MSSKLEQLQALLAPVVEALGYQCWGIEFISQGRHSLLRVYIDHANGILIDDCEKVSRQLSGVLDVEDPISVDYTLEVSSPGMDRPLFTIEQYVAHVGDQVKIKLRSPFEGRRNFQGLLRGVEEQDVVVLVDDHEYLLPIDMIDKANIIPRFD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
Protein: HEPS_HUMAN
Sequence: MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL
What is the function of this protein?
Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837).  Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933).  Plays a role in the proteolytic processing of ACE2 (PubMed:24227843).  Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890).
What are the official names of this protein?
Serine protease hepsin, Transmembrane protease serine 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
Protein: Y544_METJA
Sequence: MIAIIPAFNEEKNILKVLKDLEKLRVDAVVVDDGSKDNTSKIVEEFAKKAKINVYLIRNEKNEGKAKAIEKGTKFALSLNKYKYIIYIDGDYQHKPMDIPKLLKKLEDTNADAVFGIRKYKHIPLHRQISNFFASILTSLAVLIYSKRFYFFRDVQCGFRIIKAEFLKDMKFGDGYAVEHFIALQLAKKGAKIVEEYVSVEYHDEAVSYITTKKILEVAKQVIKFIFLE
What are the official names of this protein?
Uncharacterized protein MJ0544.
Protein: FIS_VIBCH
Sequence: MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVTELYELVLAEVEQPLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: SUCC_MYCS2
Sequence: MDLFEYQAKELFAKHNVPTSPGRVTDSAEDAKTIAEEIGRPVMVKAQVKTGGRGKAGGVKYAATPDDAFTHANNILGLDIKGHVVKKLLVAEASDIAEEYYISFLLDRANRTYLAMCSVEGGMEIEEVAATKPERLAKVPVDAVKGVDLAFARSIAEQGHLPAEVLDAAAVTIQKLWEVFVKEDATLVEVNPLVRTPDDQILALDGKVTLDENAGFRQPGHAEFEDRDATDPLELKAKENDLNYVKLDGQVGIIGNGAGLVMSTLDVVAYAGENHGGVKPANFLDIGGGASAAVMAAGLDVILGDSQVKSVFVNVFGGITACDAVANGIVQALQILGDEANKPLVVRLDGNNVEEGRRILAEANHPLVIQAETMDAGADKAAELANK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: RECU_STAAS
Sequence: MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEAYFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWKRYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_PSEMY
Sequence: MARNTAINRYRNIGICAHVDAGKTTTTERILFYTGLSHKMGEVHDGAATTDWMVQEQERGITITSAAITTFWEGSRRQYDKYRVNVIDTPGHVDFTIEVERSLRVLDGAVVVFCGTSGVEPQSETVWRQANKYGVPRIVYVNKMDRQGANFLRVVGQIKNRLGHTPVPIQIAIGAEENFEGQVDLIKMKAIYWNDDDKGTTYREEEIPAELVDLANEWRSNMVEAAAEASEELMNKYLEEGDLSAEDIKAGLRARTLASEIVPAVCGSSFKNKGVPLVLDAVIDFLPAPTEIPAIKGIHPDLADKPKEQMEESDYDERHADDNEPFSALAFKIATDPFVGTLTFVRVYSGVLESGQSVINSVKGKKERVGRMVQMHANQRDEIKEVRAGDIAALIGMKDVTTGETLCDPDKPIILERMDFPEPVISVAVEPKTKADQEKMGIALGKLAQEDPSFRVKTDEETGQTIISGMGELHLDILVDRMKREFNVEANIGKPQVSYRETITKDSVEIEGKFVRQSGGRGQFGHCWIRFSAPDVDDKGNITEGLVFTNEVVGGVVPKEYIPAIQKGIEEQMKNGVVAGYPLIGLKATVFDGSYHDVDSNEMAFKIAASMATKQLAQKGGGKVLEPIMKVEVVTPEDYMGDVMGDLNRRRGLIQGMEDSVSGKVIRAEVPLGEMFGYATDVRSMSQGRASYSMEFSKYAEAPSNIVEALVKKQG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_LEGPH
Sequence: MSTIQLEAQSRTDMGKGASRRLRRLENKVPAVIYGGSKKPMAIHFSHNKVIKALETESIYSSVFDITVDGKVEHVILKALQRHPYKPIVLHMDLQRVSSKDILVKLVPVHFINEEQSPGIKAGGIVQHTMTQVEIRCQAKDLPEFIEVDMSKVGMDDVVHLSDLKLPKGVQLTVDVADGSHDAPVVSIHAAKVSSTELEETPEVPASAVPTTDQGESAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: FMT_HALOH
Sequence: MNIVFMGSPDFAVPGLEKLYNEPGITIKAVVTQPDRKKGRGHKLRPTPVKQMAHKLGLKVLQTDNINREEFITNLRDLSPEAIVVVAFGQKLGKKVLELPSYGCINLHASLLPRYRGASPIHRAIINGDKVTGVTTMYMDEGWDTGDIIYKKEVKINREDTAGTLHDKLASIGGDLLVKTLNDIEKGVAPREKQSEDKASYAYKIDRKIGELDWSRSSEDIFNLVRGVNPWPGAYTTWKGKLLKIWWVEPLKLTVTENDKKMEAGEVITASQEDGIIVKTGDDAVKIIELQLAGRKKITADKFVLGYNIKEGDKLG
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.