PharMolix/UniProtQA huggingface dataset:
Protein: PAGN_SALTY
Sequence: MKNFFAVCIIPLVVAWSATASAKEGIYITGKAGTSVVNVYGINSTFSQDEIVNGHATLPDRTKGVFGGGVAIGYDFYDPFQLPVRLELDTTFRGETDAKGGQDIIAFGDPVHINVKNQVRMTTYMVNGYYDFHNSTAFTPYISAGVGLAHVKLSNNTIPVGFGINETLSASKNNFAWGAGIGAKYAVTDNIMIDASYKYINAGKVSISKNHYAGDEHTAYDADTKAASNDFMLGITYAF
What is the function of this protein?
Haemagglutinin that facilitates the adhesion to and invasion of epithelial mammalian cells.  Utilizes heparinated proteoglycan as a receptor to successfully invade host cells.
What are the official names of this protein?
Outer membrane protein PagN, Adhesin/invasin protein PagN.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: ACPS_ECO57
Sequence: MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWEIWKTHHQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKLGVANMHVTLADERHYACATVIIES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to the 'Ser-36' of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URK_STAAW
Sequence: MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MX_LARCR
Sequence: MNTLNQQYEEKVRPCIDLIDSLRSLGVEKDLALPAIAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLELKMKRKKEGEEWYGKISYQDYEEEIEVPADVEKKIREAQDKMAGNGVEIADDLISLEIASPDVPDLTLIALPGIARVAVKKQPENIGDQIKRLIQKFIKKQETINLVVVPCNMDIATTEALKMAQEVDPDGERTLVILTKPDLVKKGTEETVIDIVHNEVIHLKKGYMIVKCRGQKEITEKVSLPEAIEREKAFFKDHAYFHTLYNDGHATVPKLAEKLTLGLVHHIERSLPRLEEQIEEKLEQTRAELERYGNGPPTDPAEKLVFLTDKVTAFTQDAIRLTTGEELKCGDGLNVFSTLRTEFMKWNAHLNHLGEIFGKRIEREVAQYEEKYRGRELPSFINYKTFEVIAKEQIKQLEELAVKRLKNIGDAVMKVFIQLAKSSFTGFPNLLEKAMTKINYIKNRNESTAESMLRTQFKMELLVYSQDRTYSSSLSDRKREEQQREVDSDQGSVISDNEERSIVYSTDNHATLQELMVHLKSYYKIASQRLADQIPMVIRYQMLQQSAIQLQREMMQVLQDKEKSEVLLKEDFDIGSKRAAFQCRLERLMKARRFLTEF
What are the official names of this protein?
Interferon-induced GTP-binding protein Mx, Interferon-inducible Mx protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_COXBU
Sequence: MPMIDVPDNNAFDVAMRRFKRACEKAGILSKLRQIEYYEKPTSKRKRKRAAAVKRYAKKLQKEQEALERERTRY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: BST2_RAT
Sequence: MAPSFYHYLPVAMDERWEPKGWSIRRWWLVAAILVVLIGVVLVCLIVYFANAAHSEACKNGLRLQDECRNTTHLLKHQLTRAQDSLLQTEMQANSCNQTVMDLRDSLKKKVSQTQEQQARIKELENKIERLNQELENLRTQKEISTTVQVNSGGSVVVSSLLVLVAVLFLHF
What is the function of this protein?
IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells.  Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other.  The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface.  In either case, their spread as cell-free virions is restricted.  Its target viruses belong to diverse families, including retroviridae: human immunodeficiency virus type 1 (HIV-1), mouse mammary tumor virus (MMTV) and murine leukemia virus (MLV), filoviridae: ebola virus (EBOV), arenaviridae: lassa virus (LASV), and rhabdoviridae: vesicular stomatitis virus (VSV).  Can inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration.  Can stimulate signaling by LILRA4/ILT7 and consequently provide negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection (By similarity).  Plays a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells.
What are the official names of this protein?
Bone marrow stromal antigen 2, BST-2, Protein DAMP-1.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network. Cell membrane; Single-pass type II membrane protein. Cell membrane; Lipid- anchor, GPI-anchor. Late endosome. Membrane raft. Cytoplasm. Apical cell membrane. Note=Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. Forms a complex with MMP14 and localizes to the cytoplasm (By similarity).
Protein: MDTK_SHIBS
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRMPSAIILQRASR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURA_MARN8
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTDKVAAVVRFQGGHNAGHTLVIEGKKTALHLIPSGILRQDVQCLIGNGVVLSPEALLKEVRELEANGVAVRDRLKISLACPIILRTHVRIDQARERARGNDKIGTTGRGIGPAYEDKVSRRGVRLGDLCNPADFEIKLREIMSYHNFVLTEYFKEEAEDIDAALEELRQMGEEILPMAADVTDILHDYRKRGEHILFEGAQGSLLDIDLGTYPYVTSSNTTAGGTATGSGFGPLYLDYVLGITKAYTTRVGSGPFPTELFDDMGKHLAVKGNEVGTTTGRSRRCGWFDAVALRHAIQINSVSGICLTKLDVLDGLETVKVCIGYKTPNGEITRPPIGCDSYSDIEPVYEELPGWSESTVGLTSVDQLPENAKAYIRFLEEQIEAPIDIISTGPDRVETITLRHPFGE
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRTIA_ONCMY
Sequence: PRRRRSSSRPVRRRRRPRRVSRRRRRRGGRRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-1A, Iridine IA.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLMM_SERP5
Sequence: MSERKYFGTDGIRGKVGDTPITPEFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGAKLPDDVEEAIEAEMEKPLTCVESSELGKASRIIDAAGRYIEFCKGTFPSELSLKGLKIVVDCANGATYHIAPSVLRELGATVIAIGVEPDGMNINEKCGATDVRQLQERVLQEKAHVGLAFDGDGDRVMMVDHLGNKVDGDQILYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQELGWRIGAENSGHVILLDKTTTGDGIVAGLQVLTAIVRNSMSLHDLCSGMKLLPQILVNVRFAGEHNPLESEEVRKITEQVEVELAGRGRVLLRKSGTEPLIRVMVEGEDEQQVTALAHRIADAVKSAG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CD38_MACFA
Sequence: MANCEFSPVSGDKPCCRLSRRAQVCLGVCLLVLLILVVVVAVVLPRWRQQWSGSGTTSRFPETVLARCVKYTEVHPEMRHVDCQSVWDAFKGAFISKYPCNITEEDYQPLVKLGTQTVPCNKTLLWSRIKDLAHQFTQVQRDMFTLEDMLLGYLADDLTWCGEFNTFEINYQSCPDWRKDCSNNPVSVFWKTVSRRFAETACGVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQALEAWVIHGGREDSRDLCQDPTIKELESIISKRNIRFFCKNIYRPDKFLQCVKNPEDSSCLSGI
What is the function of this protein?
Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion (Probable).  Synthesizes the Ca(2+) mobilizer nicotinate-adenine dinucleotide phosphate, NAADP(+), from 2'-phospho-cADPR and nicotinic acid, as well as from NADP(+) and nicotinic acid.  Also has cADPR hydrolase activity (By similarity).
What are the official names of this protein?
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP-ribosyl cyclase 1, ADPRC 1, Cyclic ADP-ribose hydrolase 1, cADPR hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the ADP-ribosyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PRVB1_MERSE
Sequence: AFAGILADADITAALAACKAEGSFKHGEFFTKIGLKGKSAADIKKVFGIIDQDKSDFVEEDELKLFLQNFSAGARALTDAETATFLKAGDSDGDGKIGVEEFAAMVKG
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions (By similarity).
What are the official names of this protein?
Parvalbumin beta 1.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: ZN561_HUMAN
Sequence: MAAIYLSRGFFSREPICPFEEKTKVERMVEDYLASGYQDSVTFDDVAVDFTPEEWALLDTTEKYLYRDVMLENYMNLASVEWEIQPRTKRSSLQQGFLKNQIFSGIQMTRGYSGWKLCDCKNCGEVFREQFCLKTHMRVQNGGNTSEGNCYGKDTLSVHKEASTGQELSKFNPCGKVFTLTPGLAVHLEVLNARQPYKCKECGKGFKYFASLDNHMGIHTDEKLCEFQEYGRAVTASSHLKQCVAVHTGKKSKKTKKCGKSFTNFSQLYAPVKTHKGEKSFECKECGRSFRNSSCLNDHIQIHTGIKPHKCTYCGKAFTRSTQLTEHVRTHTGIKPYECKECGQAFAQYSGLSIHIRSHSGKKPYQCKECGKAFTTSTSLIQHTRIHTGEKPYECVECGKTFITSSRRSKHLKTHSGEKPFVCKICGKAFLYSSRLNVHLRTHTGEKPFVCKECGKAFAVSSRLSRHERIHTGEKPYECKDMSVTI
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 561.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOD_MYXXD
Sequence: MADTLKPEAPNPDTDAYAHESELDAHLQTKRMVINMGPSHPATHGTVRLKVELEGETIVKIDPEIGFLHRGFQKSCENVTWTQCLPYTDRLNYLSAMMNNFGFLNAVEKLIGLEIPERAQYIRVIGSELHRLTDHLTCVGATGLEMGGFAPFLLAMEFRELLHDRTAELTGARLTTSFGRVGGSNRDLPEGWIPRVHKTLDQGLALLDEMEGLLTNNRIFVDRTKGTGVISAEDAIEYGYTGPALRACGVDYDIRKTKPYWVYDRFDFDIPVGEHGDNYDRYLVRLEEMRQSIRILRQAMDTIPAGPIIVDDWRIALPPKPEVYGTIEGVMSHFKLVMEGIQVPAGEVYDATEASNGELGWYLVSDGRGRPYKVHVRAPGFPVLAAVPHIIEGKMLADLIPTFDTINMIGGEVEQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CHBG_KLEP3
Sequence: MERVLIVNADDFGLSKGQNYGIIEACRNGVVTSTTALVNGAAIDHAAQLSRSTPELAVGMHFVLTLGEPLSAMPGLTREGRLGKWIWQQAEEGRLPLEEIAHELACQYRRFVDLFGHEPTHLDSHHHVHMIAPIYPIVAAFAREKGIALRIDRQVAAQSGLDQQAARSSAGFSSEFYGEAVSEELFLQTLDASIARGERSLEVMCHPAFVDQTIMGSAYCYPRLGELDVLTSAALKAAVADRGYRLGTYRDV
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_ERWT9
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTLTGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELISAAQIDRLATLPTYDEAIARLMATMKEAAAGKLVRTLAAVRDQKEATAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: MU170_SCHPO
Sequence: MTEELFSNSETCSLSDPLTSKTLSSIENPFDDPYILSEESEILTIKTDVLRPNILNRKSSFYPEADAPVRKSNLQVKKIFENQVLNCDGIKVAITIPDTSLIAGSLLHGNIWLSYEGAKNVETGVWIKEMFLDFYGILNFKGHSEPFYSISEKYSFCNLKTSALILSKAASASIGNKGLFLKCSCKVGFPFSFIVPLDIGPGTYHSSKLELLYYISSTLTLTSLDQNIRCTRCTIPKRVITSMHNNIAELYNPISCIKSLPYLSLEEAKTTLEVHTDRSLFFSGQIIDFTICYTHNHHRRIHNIKARLLETHIFHPNTQNHYGGYCMNQAEETFASCGYLKRYQKTKTKTRAKSTWKIANKSVYSNLAPTLKNTIHAQIKIPEFCRSVNLKDQLKIDYTLEVCFSAFFKPRILSIQIPITILHSWN
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 170 protein.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at the cell tip and the barrier septum.
Protein: RL22_PSEF5
Sequence: MEVAAKLSGARISAQKARLVADQIRGKKVGEALNLLAFSSKKAAEIMKKVLESAVANAEHNEGADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y071_OSHVF
Sequence: MEIDTSVFDFHQKVKEVILKEYKLNRELIMLKRCLRYKCMSPAAFYVQVLEVNNPYLINDVTAVTRIITNMMKCVPQLRKDGGKLKDSEIKELEDFIPGYIRYLQIVSEYALILFRGNPLPAVELLKWDPKLPLASYVFVDMNDIYTVSAIREHMDVDRILFDMVLDWCNVSSGWSGNVQKIRRTFRWYYEAVFKADEVIYVDRDEISTENLILFLFVYEEVIARQQPMNAIHTHGSYWNTFLKEFSSVPITMRSQDGGNKYIRHSILTAREKIPGKHVKLRSKEFNLFIHNGRRKLPASDVYTATLQIMWELTGKCFLDSSLLNMDKLREGMMFRKIKIRWHSIRDDLVITRLHTLNREQVIMRDFLVRCNVDANAKHKRKRLKPVETLTLFEKSRMESQNITLDYLLYTHSRLISHKAWQQTNKTSTLSAAQLNSEGHVISGKPDQVESQQ
What are the official names of this protein?
Uncharacterized protein ORF71.
Protein: RTCB_TRIAD
Sequence: MERLNRNRSYQEELNFIEKINDYSYRIKLGFVPNMKVEGLFYADLPLEHLMFEELQHFCSCNGVGGFLPGVKQIGNVAALPGIVGKSIGLPDIHSGYGFAIGNIAAFDVANPKAIVSPGGVGFDINCGVRLIRTNLHERDVNPMKETLAQSLFDHIPVGVGSRGIIPMNARDLDEALEMGMDWSLREGYAWAEDKEHCEEYGRMLQADSNKISLRAKKRGLPQLGTLGAGNHYAEIQAVDEIYDSFAAKSMGINRRGQICIMVHSGSRGLGHQVATDALFNMEKAMIKDGINVNDRQLACARIASDEGQNYLKGMAAAANYAWVNRSSMTFLARQAFAKCFHTTPDDLDMHVIYDVSHNIAKIEEHVVNGKLSTLLVHRKGSTRAFPPHHPLIPVDYQLTGQPVLIGGTMGTCSFVMTGTSQGMSETYGTTCHGAGRALSRAKARRSLNYQEVLDRLNASGISIRVASPKLVMEEAPESYKDVTNVVETCHLAGISKKCFKLRPIAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: SCXM_CENSC
Sequence: KEGYLVNSYTGCKYECLKLGDNDYCLRECRQQYGKSGGYCYAFACWCTHLYEQAVVWPLPNKTCN
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  Highly potent.
What are the official names of this protein?
Toxin CsEM1, CsE M1, CsEIII.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCG5_HUMAN
Sequence: MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRGRSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC
What is the function of this protein?
Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs).  Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization.  Displays subunit-specific AMPA receptor regulation.  Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2.  Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).
What are the official names of this protein?
Voltage-dependent calcium channel gamma-5 subunit, Neuronal voltage-gated calcium channel gamma-5 subunit, Transmembrane AMPAR regulatory protein gamma-5, TARP gamma-5.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Postsynaptic density membrane.
Protein: RNB_VIBC3
Sequence: MFQDNPRLAQLKQKIQETLPKKEGTIKASDKGFGFLEVDSKTSYFVPPPYMKKCMHGDKVVAFIRTENEREVAEPSELIEQSLTRFIGRVKLFKGKLNVAPDHPQLKKLSLKAKTKKGLNEADFQEGDWVVAHLVRHPLKGDDGFFVQISHKITDANDKIAPWWVTLAENDLPNSEPAGIDDWQLKDDADLVREDLTALPFVTIDGESTKDMDDALYAQQLPNGDFALTIAIADPTAYITPEDEMDKVARERGFTIYLPGRNIPMLPRDLADELCSLMENQVRPALCCSVTIRKDGVIGDDIRFFAANIKSHARLVYDHVSDWLETGSSEQWQPSEEIAQVVRDLYAFSQARANWCETHAVVFPDRPDYRFELSADNDVVAIHADMRRTANRLVEESMITANICAGKTLQTTFGFGVFNTHAGFKAEKMADVVELMAVNGAPNADAETLATVEGFAALRRWLATQETSYLDNRIRKYQSYSEIGNQPLPHFAMGLDVYATWTSPIRKYGDMINHRLLKAHILGKAPVQTPDETVGEELALHRKHHKIAERNVADWLYARTLADEPAKETRFQAEIFDINRPGMRVRLLENGAMAFIPGALILDNKERIECNGEDGTILIDKEVVYKLGDVLEIVLTEVNQENRSLVGKPTQVFADLVSETQTSTEQPAEGAENNEPQA
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJ013_HUMAN
Sequence: MQPGGTAGPEEAPMREAEAGPPQVGLSRPTCSLPASSPGPALPPGCVSRPDSGLPTTSLDSAPAQLPAALVDPQLPEAKLPRPSSGLTVASPGSAPALRWHLQAPNGLRSVGSSRPSLGLPAASAGPKRPEVGLSRPSSGLPAAFAGPSRPQVGLELGLEEQQVSLSGPSSILSAASPGAKLPRVSLSRPSSSCLPLASFSPAQPSSWLSAAFPGPAFDFWRPLQAQNLPSSGPLQARPRPRPHSGLSTPS
What are the official names of this protein?
Putative uncharacterized protein FLJ44672.
Protein: APT_STRS7
Sequence: MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYACDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIGDYDCKVLMHFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_YERPA
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYAKKLGVDIDNLLCSQPDTGEQALEICDALTRSGAVDVIIVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKNANTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKDGDVVVGSETRVKVVKNKIAAPFKQAEFQILYGEGININGELVDLGVKHKLIEKAGAWYSYNGDKIGQGKANASNYLKENPAIAAELDKKLREMLLNGGNGEQPVAAATAEFADGADETNEEF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_HELP2
Sequence: MVNDIIADSLTRLRNASMRRLEFTQLYYAKIVVSILEIFKEKGFIKDFNVKDKDKKQSVYVQLAYDEKGHSKISEVKRLSKPGRRVYKQKNELKRFKNGYGVIVVSTSKGVITNEEAYRQNVGGEVLCSIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: Y381_MYCGE
Sequence: MIKLGWASFSNTEFAQDIFIKFANQFYKQDDAGTILFELKKTLGVNQLDEIEKNKKVIIVNQFQNSLGKFLLFNKENTKRINSLANEHISSFLKKIFRLSGFKDMLIDVQHHKKLQKCLLREIHLLVCLINSNQFSDELMQIIEWYQYLKKHSSKLFVITASSDKKPVIEPTINEYKAIFGEYLSSFHLDLKNNQSNDLFQKLLDQIKIKATSKTSLR
What are the official names of this protein?
Uncharacterized protein MG381.
Protein: PSBU_SYNR3
Sequence: MSRLFRRLSTLLLCSLLVLGVWLTQPLSVQAAEIRNKVDDKIAETAGKVDLNNASVRRFQQYPGMYPTLAGKIVVGGPYDQVEDVLKLDLTERQKELFEKYKENFTVTDPEIALNEGFDRINDGQYR
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the Lumenal side of the thylakoid membrane.