PharMolix/UniProtQA huggingface dataset:
Protein: RL34_BORGP
Sequence: MKRTYQPSRVKRNRKFGFRARMKTKGGRLILARRRAKGRMKLTVSDEKKKY
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: THIM_STAAM
Sequence: MNYLNKIRIENPLTICYTNDVVKNFTANGLLSIGASPAMSEAPEEAEEFYKVAQALLINIGTLTAQNEQDIIAIAQTANEAGLPIVFDPVAVGASTYRKQFCKLLLKSAKVSVIKGNASEILALIDDTATMKGTDSDANLDAVAIAKKAYAIYKTAIVITGKEDVIVQDNKAIVLANGSPLLARVTGAGCLLGGVIAGFLFRETEPDIEALIEAVSVFNIAAEVAAENENCGGPGTFSPLLLDTLYHLNETTYQQRIRIQEVE
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: WLS_CHICK
Sequence: MAGAIIENMSTRKLCIVGGILLVFQVIAFLVGGLIAPSPTTAVPYMSVKCIDVRKNHHKTKWLMPWGPNHCEKLKDFDEAVSRQIEANDIVFAVHIPLPSKEMSPWFQFMLFIMQLDIAFKMDNDLKENAEITLDVSLAYRDDMFNDWEEIAHAIEIRKLKCTFGSPKTLESEGRHYDCDFLPFMEIGSVAHKYYLINIRLPVNERKGINVGIGEVKDIRLVGIHQNGGFTKVWFAMKTFLTPSILIIMVWYWRRITLMTRAPVLLEKVIFALGISMTFINIPVEWFSIGFDWTWMLLFGDIRQGIFYAMLLSFWIIFCGEHMMDQNERNRLSGYWKQVGPIAVGSFCLFIFDMCERGVQLKNPFYSIWTTEVGTELAMAFIIVAGICLCLYFLFLCFMVFQVFRNISGKQSSLPAMSKARRLHYEGLIFRFKFLMLITLACAAMTVIFFIVSQVTEGHWKWGDITIQVNSAFFTGIYGMWNLYVFALMFLYAPSHKNYGEDQSNGDLGVSSGEELQLTTTITHVDGPTEVYKLARKEAQE
What is the function of this protein?
May play an essential role in Wnt signaling pathway.  May be required for Wnt-dependent patterning processes (By similarity).
What are the official names of this protein?
Protein wntless homolog, Integral membrane protein GPR177.
What is the protein family that this protein belongs to?
Belongs to the wntless family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: PIGS_SCHPO
Sequence: MSPCKWLTMFLKGCWGKIANMNHLDSCFPLRYIIGRKKASKLLCTMDSGLKSDSHEVERSNFQLNKPEKSLKRYALLSFYVIILLAIPVWWKTTHYERSSLPFEDMENAPSTVQTHLRFSPTFRILDDKGNNLTKEVQKVLEAEPQIYSYNLKVLEDDPVDYRIVLRESTDLQWFWDENNFIIDTPSKGPSELAILIVNCLWEAFSPQVMEVWSKFTRFSSTVEPSRAETKRTVQFSPQYRVLLSLLVGEGNHEPINWDIENAIQKYFNPLIEQLASLAKLNIETQIQYFVEDAEAYIKDDKFCTKHADLPNLVNNFEKYLSFSPHIREPTIHFVLYVPSPQIQPLWLENEDSNIIPTNSMLLPQWGSITTINFNVTEKKLLHDVDLKDYFRVISRDLLLLLGINDVPVSSLSATLADRLLRQRIAESCIEASDTLQNLAKLVHSMQSMAVPKEIQMYVKDTLLSLDMAYKALSQNNLNEALSYSNNAFSKSQEALFHPSMVTTIYFPDESKYGIYAPLFAPILIPLLISFIKEVKDMLRERKLHRVANVPKPN
What is the function of this protein?
Component of the GPI transamidase complex.  Involved in transfer of GPI to proteins (By similarity).
What are the official names of this protein?
GPI transamidase component PIG-S homolog.
What is the protein family that this protein belongs to?
Belongs to the PIGS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RNY_LACGA
Sequence: MINTILVPVAVAIVSVLVGGCAGYSLRKNKWETQAQNAAHDAKHILADAESKAKAVEADLASQQEAMKKAAADAKKEKILEAQEEIHHYRERVDNELNERRQEVSRQENRLLQREDAIDHKDSLLDQKDSQLTQKENQIKKLQAQVLEKEKRADQLVTEREQKLYEVAELSQEDAKKIVLDKLSDQLVKERAEMIEESNQLAKAKADHFARKVIVDAIQSSAADTVSEKTVSVVNLPNDDMKGRIIGREGRNIRSFEALTGVDVIIDDTPDVVVLSGFDPIRREIAKRALERLIKDGRIHPARIEEMVDRARKEVNDDIYEAGESALMELGIHKMHPELVKILGRLKYRTSYGQNVLSHSIEVGKLTGVMAAELGLDEKIAVRAGLLHDIGKSIDHEIEGSHVEIGVELARKYHEPDLVVNAIAAHHDDVPKLSFIAELVVAADTISSARPGARSESLENYIRRLEQLETIAKGHIGVKQAYAIQAGREIRVMVEPDKISDARTTILAHDIKNQIEQDMEYPGNIKVTVIREKRAVAIAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GET4_DROME
Sequence: MSAAETGPIASGSAVSTGQRGVSRVLAKLSQSLAGGEFYEAHMMYRTLYFRYTAQKRYQDCLELLFDGAQQLIAKEQESSAADLCLLLVDTLEKRGPQAEDTDNFLWVPRLGALIRGLNSATVERETLIQRTIKWSTALHGQYGHPVLHKLIAHVFWTEGNIESARHHYLLCQDGSLCGRVLIEISQSRGFQGEMDLFLVQAVLQQLSLKDRKTAEDTFTEYTRYHAKLLKHEFPYKEPLVNFLYFLFRLIDAKRVAGFRALRKLYDPSLKRDTSFLKYVAKIGVLYFDEHPEAAHSGPPGLGGMFGDIFNRLMAGFEEDDADDHDTTLRRQNENNELE
What is the function of this protein?
May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane.
What are the official names of this protein?
Golgi to ER traffic protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the GET4 family.
Protein: POST_XENLA
Sequence: MEFVERYVNKYASADYHSCADESVTHQFKSLLTQCQRYNNKVKCNHLAKMVKKIKMANEILALLKMKVIAENKAEQWRNEKVQFREDLEKFGESLIVAASTSEEHISELEELREKVELLAKQNDLLEEKLKDCEERCRLREQEVISLESKAGYELNVPVSVCPVTEQEIKDGEQGIRPQTLPSPTLFSPQSECARQRINNTYVPTDNNIHSNSALKIQEVISLTQILGKFDTNLSPISLYNKLEAVVKQYNLGNKDACALLRAWLPYQLAAELRPPVGKHIGTLSNINENWGSTSERLRELQRILGGRDIRGTNALENARYRKGDDPMLFCTDYLSLYKVVFNCPDMLPDEPNFLYSMANKCNVDYNTRTALRYATSYNNFINTLRDWSQESFEFQRHISVAYKKKQSRRFPRKCYSCGKYGHIARFCRTSANQHDTYPIHSIQRQEGDAQENLNDYLLDHSPPSETETVVSSDNIDTGSNSAGDQKESQNEPKREFHTPPCKTGKEGTTAPPFIPWVNIPLWLYSSWSHIAMLMLMDNIAQFAQGVPNTNMPVF
What is the function of this protein?
This protein is expressed exclusively in posterior mesoderm and ectoderm of early embryos suggesting a possible role in organization of anteroposterior axis.
What are the official names of this protein?
Posterior protein, xPO.
Protein: YAN2_YEAST
Sequence: MTGYFLPPQTSSYTFRFAKVDDSAILSVGGNVAFECCAQEQPPITSTDFTINGIKPWQGSLPDNIGGTVYMYAGYYYPLKVVYSNAVSWGTLPISVELPDGTTVSDDFEGYVYSFDDDLSQSNCTIPDPSKHTTSIVTTTTELWTGTFTSTSTEMTTVTGTNGQPTDETVIVAKAPTTATSSSLSSSSSEQITSSITS
What are the official names of this protein?
Putative uncharacterized protein YAR062W.
What is the protein family that this protein belongs to?
Belongs to the flocculin family.
Protein: GCSH_CLOB6
Sequence: MKVLNNLLYTGDHEWVRVEDNKAYIGISDCAQRMLSDIVFVELPEVDDEIAKGETFATIESVKAASDSYMPVSGTIVEINEELEDNPAALNEDPYGSWIVAIEMADKNELEELIKPEVYEKICEELDKEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: BACA_BACIU
Sequence: MIILDNSIQTKSKAYSISKLITINTLGPEGTSSEYAAKNFITNFTLLQGVNSKLSLHDTFESCIEKTLQSPLEYTIVPHAYDGIKHFYMRPDLQLLQIFRCDTPMYGLAVRPGFEYTDDMLDKAVIVSHPSPINLIKYFTRKDVTFDLVNSTSAAAKRVKDGLSDIALTNELARQKYGLHFVKTFKSIPMSWSLFGKGEIHDEN
What is the function of this protein?
Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin.  Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase.  BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate.  BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1-propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro-hydroxyphenylpyruvate (en-H2HPP).  En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic-delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP).  BacA isomerizes only the pro-R double bond in prephenate.
What are the official names of this protein?
Prephenate decarboxylase, Bacilysin biosynthesis protein BacA, Non-aromatizing prephenate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the prephenate decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_PROMS
Sequence: MMTLRDLINKLLGRETSSANTARERLQLVLAHDRVDMSSLTTDLLDKMRKEILDVVAKYVEIDFDEVAVSLETEDRMTALVANLPIKRTISGEIKFKKADKANKDIKK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: YAER_ECOLI
Sequence: MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSWKGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCETIRVDPYTQKRFTFFNDPDGLPLELYEQ
What are the official names of this protein?
Uncharacterized protein YaeR.
What is the protein family that this protein belongs to?
To B.subtilis YwkD.
Protein: ARGE_ESCF3
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNAGLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDTLRDVDVTKLKKPLYILATADEETSMAGARYFSETTSLRPDCAIIGEPTSLQPVRAHKGHISNTIRVMGQSGHSSDPARGVNAIELMHDAIGHILQLRDTLKERYHYEAFTVPYPTLNLGHIHGGDAANRICACCELHMDIRPLPGMTLNDLNGLLNEALAPVSERWPGRLTVEELHPPIPGYECPPDHQLVEVVEKLLGTHTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_SALAI
Sequence: MRDRVTAARRVVVKIGSSSLTTATGGLDDGRVDALVDTLGGLAAQGREVVLVSSGAIAAGLAPLGLTRRPRDLATQQAAASVGQGLLIGRYAAAFARHHLTVGQVLLTVDDMTRRAHYRNAYRTLRKLLDLRAVPIVNENDTVATEEIRFGDNDRLAALVAALVDTDLLVLLSDVDALWTGDPTRPGSTPIAEVHDARDLSGVAIGGAGRSGVGTGGMVTKVEAARIATGFGIPVVLTSADLAAEALDGKPVGTLFHPSPRRPAARLFWLAHATSPRGRLHLDPGAVEAVVDRRKSLLAAGISAVQGAFTAGDPVDLVDTEGVPVARGLVNYDAVELPGLLGRSTSELATALGPAYEREVVHCDDLVLL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_MYCSJ
Sequence: MSSDPGYQAPVVTVSSSIPRRGVGDSVLIVPVVTRDDAAAVLAAAPFLDKDAVREIEAALKSLGATGGEGQTHRLVVSALPVASVLTIGLGKERDEWPADTVRRVAGNAARSLDKVAAVLTTLSALDLEAAIEGLILGSYRFTEFRSAKTAPKDGGLRAITALSQESKSRARDAAQRATDIATAVATARDFVNTPPSHLHPDEFAKRAKALGEAAGLEVEILDDKALVKAGYGGIVGVGKGSSRPPRLVRLSHKGAVRTRTRGARTGGSKRVALVGKGITFDTGGISIKPAANMHHMTSDMGGAAAVIATVVLAAKQKLPIDVIATVPMAENMPSATAQRPGDVLTQYGGTTVEVLNTDAEGRLILADAIVRACEDNPDYLIETSTLTGAQTVALGSRTPGVMGSDAFRDRVATLSQQVGENAWAMPLPEELKDDLKSTVADLANVSGSRFAGMLVAGTYLREFVADGVEWAHIDVAAPAYNSGGPWGYTPKGGTGVPTRTMFAVLEEIAREG
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB_BP186
Sequence: MFHCPKCHHAAHARTSRYLTENTKERYHQCQNINCSCTFMTMETIERFIVTPGAIDPAPPHPTVGGQRPLWL
What are the official names of this protein?
Late control gene B protein, GpB.
Protein: HDOX2_STAAM
Sequence: MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (staphylobilin-producing) 2, Heme-degrading monooxygenase 2, Iron-regulated surface determinant 2, Iron-responsive surface determinant 2.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIPKM_ARATH
Sequence: MAEDSNSSESIIVNVTGDDNKSALFGKYDLGKLLGSGAFAKVYQAEDLQNGGESVAIKVVQKKRLKDGLTAHVKREISVMRRLRHPHIVLLSEVLATKTKIYFVMELAKGGELFSRVTSNRFTESLSRKYFRQLISAVRYCHARGVFHRDLKPENLLLDENRDLKVSDFGLSAMKEQIHPDGMLHTLCGTPAYVAPELLLKKGYDGSKADIWSCGVVLFLLNAGYLPFRDPNIMGLYRKIHKAQYKLPDWTSSDLRKLLRRLLEPNPELRITVEEILKDPWFNHGVDPSEIIGIQADDYDLEENGKILNAFDLISSASSSNLSGLFGNFVTPDHCDQFVSDESTAVIMRKVEEVAKQLNLRIAKKKERAIKLEGPHGVANVVVKVRRLTNELVMVEMKNKQRDVGLVWADALRQKLRRLINQPVYKVPDKP
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting serine/threonine-protein kinase 22, SNF1-related kinase 3.19, SOS2-like protein kinase PKS14.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: RS9_CYAP4
Sequence: MQLVEQSKRATYIGTGRRKSSVARVRLVPGTGQLTINGKSGELYLQFNPTYLAIAKAPLESLGLENDYDILVNTSGGGLTGQADSIRLGVARALCQLDPENRKPLKVEGYLTRDPRAKERKKYGLRKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: CYTSA_DANRE
Sequence: MKKAGRPVGNKAASGGGKGDSVTAGNCAGKNTVKSPTSAPLSKVKSNDDLLAAMAGSSAGTNNSVAKGKKSTSTHSTSCGTNTNNPDTKTKTTSGPSGKRTTSMTSKESNSSRERLRNSRNSSSKKQSSTGASDRAQPKHSRALAQTSDSESRMSKSKSDGQLSDKVALEAKVKNLLGLAKSKDVEILQLRGELRDMRVQLGLPEEDEEEERPPEREAAAVITAADVESTLLLLQEQNQAIRGELNLLKNENRMLKDRLNALGFSLEQRLDGADKTFGFPSTSPELSSGGAGAHGDCATVASSVEGSAPGSMEDLLTGGQRSGSTDNLDSESSEVYQAVTSSDDALDAPSGCGSSSSSESEGGPPACRSSSRKGSSGNTSEVSVACLTERIHQMEENQHSTSEELQATLQELADLQQITQELNGENERLGEEKVLLMDSLCQQSDKLEHCGRQIEYFRSLLDEHGVAYSVDEDIKSGRYMELEQRYVELAENARFEREQLLGVQQHLSNTLKMAEQDNAEAQNVIAALKERNHHMERLLDVERQERASMAAVLEECKAAVNNDQAELSRCRVLLEQERQKVAELYSIHNAGDKSDIHQLLEGVRLDKEEAEAKASKLQDDLGHARSEVACLQDTLNKLDAEYRDFQSVVQKELAEQKRAIEKQREDLQEKETEIGDMKETIFELEDEVEQHRAVKLHDNLIISDLENSMKKLQDQKHDMEREIKILHRRLREESAEWRQFQADLQTAVVIANDIKSEAQEEIGDLRRRLQEAQEKNEKLGKEIEEVKNRKQDEERGRVYNYMNAVERDLAALRQGMGLSRRPSTSSEPSPTVKTLIKSFDSASQGPGANATAVAAAAAAAAAAAAVTVTSTTPTAPLPRTPLSPSPMKTPPAAAVSPIQRHSITGSMAAAKPLSSLADKRPSYTDISMPAEHLLRAANSRPASALQRVSNMDTSKTITVSRRSSEEPKRDISTPDGGPASSLISMSSAAALSSSSSPTASVNPTARSRLREERKDPLSALAREYGGSKRNALLRWCQKKTEGYQNIDITNFSSSWNDGLAFCAVLHTYLPAHIPYQELNSQDKRRNFTLAFQAAESVGIKSTLDITDMVHTERPDWQSVMTYVTSIYKYFET
What is the function of this protein?
Involved in cytokinesis and spindle organization.  May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration (By similarity).
What are the official names of this protein?
Cytospin-A, SPECC1-like protein, Sperm antigen with calponin homology and coiled-coil domains 1-like.
What is the protein family that this protein belongs to?
Belongs to the cytospin-A family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cell junction, gap junction. Note=Colocalizes with beta-tubulin, acetylated alpha- tubulin and F-actin. Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center (By similarity).
Protein: TYPH_SHEB5
Sequence: MFLAQEIIRKKRNGLALCSEEIQFFVQGITTNSVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLELNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIPGYQTEPSSELFRKVVKEVGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLACNLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLTDMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYEVTMGLCAEMLLLGGLASNEADARAKLNRVLDNGRAAELFGKMVSGLGGPADFVENYSKYLPQSQIIRPVFADMQGYAYSMDTRELGLAVVTLGGGRRKPGDALDYSVGLTQVCALGDKVDSSTPIAVIHAQSEAAFAEAELAVKKAIHIGETAPEKTPEIYAYIRASDL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: DXS1_CERS4
Sequence: MTNPTPRPETPLLDRVCCPADMKALSDAELERLADEVRSEVISVVAETGGHLGSSLGVVELTVALHAVFNTPTDKLVWDVGHQCYPHKILTGRREQMRTLRQKGGLSGFTKRSESAYDPFGAAHSSTSISAALGFAMGRELGQPVGDTIAVIGDGSITAGMAYEALNHAGHLNKRLFVILNDNDMSIAPPVGALARYLVNLSSKAPFATLRAAADGLEASLPGPLRDGARRARQLVTGMPGGGTLFEELGFTYVGPIDGHDMEALLQTLRAARARTTGPVLIHVVTKKGKGYAPAENAPDKYHGVNKFDPVTGEQKKSVANAPNYTKVFGSTLTEEAARDPRIVAITAAMPSGTGVDIMQKRFPNRVFDVGIAEQHAVTFAAGLAGAGMKPFCAIYSSFLQRGYDQIAHDVALQNLPVRFVIDRAGLVGADGATHAGAFDVGFITSLPNMTVMAAADEAELIHMIATAVAFDEGPIAFRFPRGEGVGVEMPERGTVLEPGRGRVVREGTDVAILSFGAHLHEALQAAKLLEAEGVSVTVADARFSRPLDTGLIDQLVRHHAALVTVEQGAMGGFGAHVMHYLANSGGFDGGLALRVMTLPDRFIEQASPEDMYADAGLRAEDIAATARGALARGRVMPLRQTAKPRAV
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 1, 1-deoxyxylulose-5-phosphate synthase 1, DXP synthase 1, DXPS 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SNU13_YEAST
Sequence: MSAPNPKAFPLADAALTQQILDVVQQAANLRQLKKGANEATKTLNRGISEFIIMAADCEPIEILLHLPLLCEDKNVPYVFVPSRVALGRACGVSRPVIAASITTNDASAIKTQIYAVKDKIETLLI
What is the function of this protein?
Common component of the spliceosome and rRNA processing machinery.  In association with the spliceosomal U4/U6. U5 tri-snRNP particle, required for splicing of pre-mRNA.  In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs.  Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.
What are the official names of this protein?
13 kDa ribonucleoprotein-associated protein, Small nuclear ribonucleoprotein-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL15_MYCPA
Sequence: MTIKLHDLKPARGSKTPRTRVGRGEGSKGKTAGRGTKGTKARKNVPVTFEGGQMPIHMRLPKLKGFRNRFRTEYEIVNVGDINRLFPQGGSVGVDELVAKGAVRRNSLVKVLGDGKLTVKVEVSAHKFSGSAREKITAAGGSVTEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GCYA1_RAT
Sequence: MFCRKFKDLKITGECPFSLLAPGQVPTEPIEEVAGVSESCQATLPTCQEFAENAEGSHPQRKTSRNRVYLHTLAESIGKLIFPEFERLNLALQRTLAKHKIKENRNSSEKEDLERIIAEEAIAAGVPVEVLKDSLGEELFKICYEEDEHILGVVGGTLKDFLNSFSTLLKQSSHCQEAERRGRLEDASILCLDKDQDFLNVYYFFPKRTTALLLPGIIKAAARILYESHVEVSLMPPCFRSECTEFVNQPYLLYSVHVKSTKPSLSPGKPQSSLVIPTSLFCKTFPFHFMLDRDLAILQLGNGIRRLVNKRDFQGKPNFEEFFEILTPKINQTFSGIMTMLNMQFVIRVRRWDNLVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLEDFTGRGLYLSDIPIHNALRDVVLIGEQARAQDGLKKRLGKLKATLEHAHQALEEEKKKTVDLLCSIFPSEVAQQLWQGQIVQAKKFNEVTMLFSDIVGFTAICSQCSPLQVITMLNALYTRFDQQCGELDVYKVETIGDAYCVAGGLHRESDTHAVQIALMALKMMELSNEVMSPHGEPIKMRIGLHSGSVFAGVVGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRLLKDCPGFVFTPRSREELPPNFPSDIPGICHFLDAYQHQGPNSKPWFQQKDAEDGNANFLGKASGVD
What are the official names of this protein?
Guanylate cyclase soluble subunit alpha-1, GCS-alpha-1, Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, Soluble guanylate cyclase large subunit.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLH_YEAST
Sequence: MSKFTWKELIQLGSPSKAYESSLACIAHIDMNAFFAQVEQMRCGLSKEDPVVCVQWNSIIAVSYAARKYGISRMDTIQEALKKCSNLIPIHTAVFKKGEDFWQYHDGCGSWVQDPAKQISVEDHKVSLEPYRRESRKALKIFKSACDLVERASIDEVFLDLGRICFNMLMFDNEYELTGDLKLKDALSNIREAFIGGNYDINSHLPLIPEKIKSLKFEGDVFNPEGRDLITDWDDVILALGSQVCKGIRDSIKDILGYTTSCGLSSTKNVCKLASNYKKPDAQTIVKNDCLLDFLDCGKFEITSFWTLGGVLGKELIDVLDLPHENSIKHIRETWPDNAGQLKEFLDAKVKQSDYDRSTSNIDPLKTADLAEKLFKLSRGRYGLPLSSRPVVKSMMSNKNLRGKSCNSIVDCISWLEVFCAELTSRIQDLEQEYNKIVIPRTVSISLKTKSYEVYRKSGPVAYKGINFQSHELLKVGIKFVTDLDIKGKNKSYYPLTKLSMTITNFDIIDLQKTVVDMFGNQVHTFKSSAGKEDEEKTTSSKADEKTPKLECCKYQVTFTDQKALQEHADYHLALKLSEGLNGAEESSKNLSFGEKRLLFSRKRPNSQHTATPQKKQVTSSKNILSFFTRKK
What is the function of this protein?
DNA polymerase specifically involved in DNA repair.  Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls.  Plays an important role in the repair of UV-induced pyrimidine dimers.  Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions.  Efficiently incorporates nucleotides opposite to other UV or oxidative DNA damages like O(6)-methylguanine, 7,8-dihydro-8-oxoguanine, 2,6-diamino-4-hydroxy-5-formamidopyrimidine of 2'-deoxyguanosine (FaPydG), or p-benzoquinone DNA adducts.
What are the official names of this protein?
DNA polymerase eta, Radiation-sensitive protein 30.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_BRADU
Sequence: MSDSAVQRSSGRGRFITFEGGEGTGKSTQIKKLADRLKAARMRTLVTREPGGSPGAEIMRHLVLSGMGKLLGPEAETLLFAAARDDHVHTVIEPALKQGIWVLCDRFADSTRAYQGSLGSVSPGLINAMQRVTIGDLKPDLTIILDLPVEIGLQRAAARRGSGTPDRFEGEQLSFHQGLREAYRKIAADEPARCVLIDANSDPDTVAGRVWSALRDRLLPTPASVVSV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: LOLD_FRAT1
Sequence: MNDVVLSCKNVSKKYTEFKTDIAILKDVNLEIKKGEKVAILGLSGSGKTTLLNVLGGLDKCSAGEVYLMGERFDNQSVNKRAKMRNKHLGFIYQLHHLLPEFTAIENVMIPLAITKKYTKKESIKLANEILKKVGLDHRADHKPAELSGGERQRVAIARALVTNPNCILADEPTGNLDSQRSESIFALMQQLSDDFGTSFVIVTHDEKLASRMNKIYRLVDGELELVINSN
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.