PharMolix/UniProtQA huggingface dataset:
Protein: MOV10_BOVIN
Sequence: MPSKFSCRQLRETGQRFENFLVDRGQDRETDRERLRTIYNQDFKTSFGTPAPGFSSMLYGMKIANLAYVTKTRVRFFGLDRWADVWFPEKRRMKPGLEMSKHHRSLLATIFHDRAEYMHGKHGVNVEVQGPHEARDGQLLIRLDLNRKEVLTLRLRNGGTQPVTLTHLFPFCRTPQFSFCNGDRELPCLLGPGECYELHVHCKTSFVGYFPATVLWELLGPGEPGSEGAGTFYIARFLAAVAHSPLAAQLKPTTPFKRTQVSRNPVVTRRIEEGERPDRAKNYDLEFSLPLGTYYPPPRLRQLLPVLLRGTSIFTAPKEIAEIKAQLQTTLKWRNYEVKLRLLLHLEELQMEHDIRHYDLESVPMTWDPIDRNPRLLTLEVPGVAESRPSVLRGDHLFALLSSETHHEDPVTYKGFVHKVELDRVKLSFSTSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWPLEPMLFPVASRGVPLLPSDVKLKLYDRSLESNPEQLQAMKHIVMGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGADLLCQRLRVHLPSSIYRLLAPSRDIHLVPEDIKPCCNWDAKKGDFVFPSKKKLQEYRVLITTLITASRLVSAQFPIDHFTHIFIDEAGHAMEPESLVAIAGLMEVKEADNPGGQLVLAGDPRQLGPVLRCPLTQKHGLGYSLLERLLTFNALYKKGPDGYNPQFITKLLRNYRSHPTILDVPNRLYYDGELQACADVVDRERFCRWEGLPRQDFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKQLLAPSSKKGKARLSPRSVGVISPYRKQVEKIRYCITKLDKQLRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVTRAKALLIVVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQNLLQGLSKLSPSTSGLKSHDYLPQEREGEEGLSLQVEPEWRNEL
What is the function of this protein?
5' to 3' RNA helicase that is involved in a number of cellular roles ranging from mRNA metabolism and translation, modulation of viral infectivity, inhibition of retrotransposition, or regulation of synaptic transmission.  Plays an important role in innate antiviral immunity by promoting type I interferon production.  Mechanistically, specifically uses IKKepsilon/IKBKE as the mediator kinase for IRF3 activation.  Contributes to UPF1 mRNA target degradation by translocation along 3' UTRs.  Required for microRNA (miRNA)-mediated gene silencing by the RNA-induced silencing complex (RISC).  Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC.  In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2.  Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1.  Facilitates LINE-1 uridylation by TUT4 and TUT7 (By similarity).  Required for embryonic viability and for normal central nervous system development and function.  Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity).  May function as a messenger ribonucleoprotein (mRNP) clearance factor (By similarity).
What are the official names of this protein?
Putative helicase MOV-10.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cytoplasm, Stress granule. Nucleus. Cytoplasm. Note=Co-enriched in cytoplasmic foci with TUT4 (By similarity). In developing neurons, localizes both in nucleus and cytoplasm, but in the adulthood it is only cytoplasmic (By similarity).
Protein: TRM82_PICGU
Sequence: MKHPFQIIVADTTGRYLFTTVKNVLLVIDLTSGKLVGQWKDELDNSDFLKKKYEEKFDKENDSKRQKSESGQAKVSKIPTPGPGAPPIYNYIRALRLSSDEKYLFATTDSDKAVVIFTIDHSKDNCLELKKRQPFSKRPCALSVDEDRLVVADKFGDVYSIAIEDDQVVNEKELTPILGHVSMLSDVAIVSNDKKKFIITGDRDEHIRISNYPKSFVIKNFLFGHHEFVSCLHVPNFDQSLLISGGGDDYLCLWRWYEGQLVAKIELRELIAPFLTDSHLPPERFLTETSPKEISVARILTFTNKKTGLNILVVLCEQTKAVLLFEIDAKLSVRHLQTISYEDNVLDMCYIEATNTLISAHDSDKNQLFQQQKFDEETNNFTPTTETMDAVAELNPIDVNSRNDFLPLYYINTLRKRSEH
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82, Transfer RNA methyltransferase 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACT_LUMRU
Sequence: EVTALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFDQEMGTAASSSSLEKSYELPDGQVITIGNERFRCPESMFQPAFLGMESAGIHETTFNSIMKCDVDIRKDLYANTVMSGGTTMFPGIADRMQKEITSMAPSGMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: CAPSD_BPPHK
Sequence: MSNVQTSAEREIVDLSHLAFDCGMIGRLKTVSWTPVIAGDSFELDAVGALRLSPLRRGLAIDSKVDFFTFYIPHRHVYGDQWIQFMRDGVDASPLPSVTTTKYPDDAGYVGTIVPKSNRIPKFLHQSYLNIYNNYFRAPWMPERTEANPSNLDRDDSRYGFRCCHLKTIWSAPLPPETKLAEQMGIESNSIDIMGLQAAYAQLHTEQERTYFMQRYRDVISSFGGSTSYDADNRPLLVMHTDFWASGYDVDGTDQSSLGQFSGRVQQTFKHSVPRFFVPEHGVMMTLMLVRFPPISPLEHHYLVGRNNLTYTDLAGDPALIGNLPPREISYQDLFRDGRPGIKIKVAESIWYRTHPDYVNYKYQLLEGFPFLDDAPGTTSGDDLQKAILIDHNDYNACFQSQQLLQWNNQARYNVNVYRHIPTVRDSIMTS
What is the function of this protein?
Assembles to form an icosahedral capsid with a T=1 symmetry, about 30 nm in diameter, and consisting of 60 capsid proteins F.  Upon virus binding to host cell, one of the spikes dissociates from the capsid and the virus interacts with LPS through the exposed EF loops on the F proteins.  After the genome had been ejected, the channel formed by the F proteins at the unique fivefold axis remains open.
What are the official names of this protein?
Capsid protein F, F protein, GPF.
What is the protein family that this protein belongs to?
Belongs to the microviridae F protein family.
What are the subcellular locations of this protein?
Virion.
Protein: WRN_CAEEL
Sequence: MISDDDDLPSTRPGSVNEELPETEPEDNDELPETEPESDSDKPTVTSNKTENQVADEDYDSFDDFVPSQTHTASKIPVKNKRAKKCTVESDSSSSDDSDQGDDCEFIPACDETQEVPKIKRGYTLRTRASVKNKCDDSWDDGIDEEDVSKRSEDTLNDSFVDPEFMDSVLDNQLTIKGKKQFLDDGEFFTDRNVPQIDEATKMKWASMTSPPQEALNALNEFFGHKGFREKQWDVVRNVLGGKDQFVLMSTGYGKSVCYQLPSLLLNSMTVVVSPLISLMNDQVTTLVSKGIDAVKLDGHSTQIEWDQVANNMHRIRFIYMSPEMVTSQKGLELLTSCRKHISLLAIDEAHCVSQWGHDFRNSYRHLAEIRNRSDLCNIPMIALTATATVRVRDDVIANLRLRKPLITTTSFDRKNLYISVHSSKDMAEDLGLFMKTDEVKGRHFGGPTIIYCQTKQMVDDVNCVLRRIGVRSAHYHAGLTKNQREKAHTDFMRDKITTIVATVAFGMGIDKPDVRNVIHYGCPNNIESYYQEIGRAGRDGSPSICRVFWAPKDLNTIKFKLRNSQQKEEVVENLTMMLRQLELVLTTVGCRRYQLLKHFDPSYAKPPTMQADCCDRCTEMLNGNQDSSSSIVDVTTESKWLFQVINEMYNGKTGIGKPIEFLRGSSKEDWRIKTTSQQKLFGIGKHIPDKWWKALAASLRIAGYLGEVRLMQMKFGSCITLSELGERWLLTGKEMKIDATPILLQGKKEKAAPSTVPGASRSQSTKSSTEIPTKILGANKIREYEPANENEQLMNLKKQEVTGLPEKIDQLRSRLDDIRVGIANMHEVAPFQIVSNTVLDCFANLRPTSASNLEMIDGMSAQQKSRYGKRFVDCVVQFSKETGIATNVNANDMIPPELISKMQKVLSDAVRRVYTEHLISRSTAKEVATARGISEGTVYSYLAMAVEKGLPLHLDKLNVSRKNIAMALNAVRVHLGSNVAVLTPWVEAMGVVPDFNQLKLIRAILIYEYGLDTSENQEKPDIQSMPSTSNPSTIKTVPSTPSSSLRAPPLKKFKL
What is the function of this protein?
Essential for the formation of DNA replication focal centers; stably associates with foci elements generating binding sites for RP-A.  Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity.  May be involved in the control of genomic stability (By similarity).
What are the official names of this protein?
ATP-dependent helicase wrn-1, Werner syndrome protein homolog.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENGB_BACC3
Sequence: MKVTKADIVISAVKPEQYPDGDLPEIALAGRSNVGKSSFINKILNRKKLVRISSKPGKTQTLNFFLINEMMHFVDVPGYGYAKVSKTERAAWGKMIETYFTTREQLDAAVLVVDLRHKPTNDDVMMYDFLKHYDIPTIIIATKADKIPKGKWQKHLKVVKETLDIESGDEVVLFSSETGLGKEEAWKAIHKFTKTKNA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: COAX_THET2
Sequence: MLLAVDIGNTSTALGLFSGEELIAHFRIHTDRMRMESEYRVILKNLFALEDLPPPKAALLASVVPPVEREMKRAIERLFGVEARVVEAADTGLEVLIDNPREAGADRLVNAVGALAYPSPTGRYIVVDFGTATTFDLVEAPNRYLGGAIAIGPQTAADALAQRTAKLPRIDLTPPKAAVGKNTLEALRSGLVLGYAALVEGMVRRFKEEAGEALVIATGGFAETLRPLCPCFDVVDEDLTLKGLLRIHLERG
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MC5R_RAT
Sequence: MNSSSHLTLLDLTLNASEDNILGQNVNNKSSACEDMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETITIYLINNKHVVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIVCLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRASMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCACFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIICCHGFRRTCTLLGRY
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  This receptor is a possible mediator of the immunomodulation properties of melanocortins.
What are the official names of this protein?
Melanocortin receptor 5, MC5-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: D14_BPT5
Sequence: MAVDSREKGKRGEYQVRDILRERTGLEWERVPGSGAFGQSHGLKGDIYLPPQSGHISKYCFEVKWYKDDNISSNLFNVGESTLEKWWQQCSREGEQMNSKPALIFKKDRGQWLIALDSSDPMVDNLMSRTHMVLNKKDMEIVIGLFEPWLHHASVEDLIK
What are the official names of this protein?
Protein D14.
Protein: MTND_SYNS3
Sequence: MTELRIYATRGAGVEADRDSAVAAAPEALLSTSNAEQISAQLKTRGIKFQRWPSKPKLEQGAMQEQILEAYASLIASVQKNEGYQTVDVMRVERDQISGSTLRQTFRQEHQHAEDEVRFFVEGCGLFALHIKDEVLQVICEANDWIAIPAGTRHWFDMGVDPNYCVIRFFKNSGGWAASFTHDPIADHYPGLDQARKQTTQG
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: GPAN1_MOUSE
Sequence: MVGSLACHILALPSLHFLVSLTGMSRPSFIEFTPAADSSDLWKDGQQQPQQEKAEPVLDGAAARAFYEALIADDSSSSKPQRAEPMRERKKKRRRVTREPAAAGVPRQGRALEDEDRMAQWILLAAQNGDLTELRRLLEPQEAGGAGGNINARDAFWWTPLMCAARAGQGAAVRYLLGRGAAWVGVCDLGGRDAAQLAEEAGFPEVARMVRESHGETRSPENQNRSTPSSSQFCEDCGAHFEDSNHHTSTAHLLSLSRRPQPSNLPLGVPTSSPGFRLLLRGGWEPGMGLGPRGEGRANPIPTILKRDQEGLGYRSPPQPRVTHFAARDTRAVSGRERVPRVATLSQRENRRQEEKGRAWERDLRLYMNLEF
What are the official names of this protein?
G patch domain and ankyrin repeat-containing protein 1, G5 protein, HLA-B-associated transcript 4.
Protein: BBR_HORVU
Sequence: MDDDGSLSIRNWGFYETMKGNLGLQLMPSVTGGHRDTKPLLPNGTFLQHHTPPHHPPHSHHPRDYGNGEPSGGMPAEPPAIHMDFVRNEAWMHPSQHQHQHQHQHQHQHQHQHQLQHQHQHQHSRELKVLNAVPVGPAPHIGHPGHAVHHHPTGFGMMPDARGAHTLQMMQPQEPPVPDEEKITPPLVEDHSVVGSKPPVKKRQQGRQPKVPKPKKPKKDATPGEDGAPKARAPRSRGPLKPVEMVINGIDFDISRIPTPVCSCTGAPQQCYRWGAGGWQSACCTTSISTYPLPMNTKRRGARIAGRKMSQGAFKKVLEKLAGEGYNLNNPIDLKTFWAKHGTNKFVTIR
What is the function of this protein?
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.  Positively regulates the homeotic gene BKN3.
What are the official names of this protein?
Protein Barley B recombinant, Protein BBR.
What is the protein family that this protein belongs to?
Belongs to the BBR/BPC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RFCL_METJA
Sequence: MLSWVEKYRPKSLKDVAGHEKVKEKLKTWIESYLKGETPKPILLVGPPGCGKTTLAYALANDYGFEVIELNASDKRNSSAIKKVVGHAATSSSIFGKKFLIVLDEVDGISGKEDAGGVSELIKVIKKAKNPIILTANDAYAPSIRSLLPYVEVIQLNPVHTNSVYKVLKKIAEKEGLDVDDKTLKMIAQHSAGDLRSAINDLEALALSGDLSYEAAQKLPDRKREANIFDALRVILKTTHYGIATTALMNVDETPDVVIEWIAENVPKEYEKPEEVARAFEYLSKADRYLGRVMRRQNYSFWKYATTLMTAGVALSKDEKYRKWTPYSYPKIFRLLTKTKAEREILNKILKKIGEKTHTSSKRARFDLQMLKLLAKENPSVAADLVDYFEIKEDELKVLVGDKLASEILKILKEKKKLERKKKKEKEKLEKEKKKEEKAKEKQSNLIIQPKEIKEEVKAEVEKKEEVKEKIVEKPKAEEVKEKSKTEEKETKKDKKKGKKKKEDKGKQLTLDAFFK
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: LFTR_BRUAB
Sequence: MTAEAPPDDDIIEPEMLLRAYATGIFPMAEEADDPEVFWVRPEKRGVIPLDGFHIPRSLQKTIRQGIFKIRLDSNFAGVIEGCASGTGERARTWINEPIRRAYAKLFEIGHCHTVEAWYEGKLAGGLYGVTLGRAFFGESMFTRKRDASKVCLAYLVQHLSRQGFVLLDTQFTTPHLERFGALEVPRKEYEEMLERALEGIARF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_LACLS
Sequence: MRCPKCSSEESKVVDSRQAEDAIRRRRVCESCGFRFTTFERIEEMPLLVIKKDDKREPFNREKIVRGLVRSAYKRPVSSEDIETTVANVERKIRQLDSNEVESDVIGEFVMQELAELDDITYIRFASVYRSFKDVSELEELLKNITKK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: ENGB_SHEDO
Sequence: MSESIMDFRRAKFLISAPDIAHLNQYLPGDVGVEIAFAGRSNAGKSSALNALTEQKSLARTSKTPGRTQLINVFALDDDRRLVDLPGYGFAQVPLALKNKWQQALGEYLQKRACLSGVVVLMDIRHPLKDLDMQMIEWAVASEIPVLALLTKSDKLAQSAKMKTVNEVRSALADFGDWVKVEPFSSLKGTGKPKVLSILNEWCHPQWLMDAMAQESPED
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CSPE_ECO57
Sequence: MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTLAEGQRVEFEITNGAKGPSAANVIAL
What are the official names of this protein?
Cold shock-like protein CspE, CSP-E.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_PHATC
Sequence: MEALVYTFLLIGTLIVIFFAVFFRETPRIIKK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DPOL_EBVG
Sequence: MSGGLFYNPFLRPNKGLLKKPDKEYLRLIPKCFQTPGAAGVVDVRGPQTPLCFYQDSLTVVGGDEDGKGMWWRQRAQEGTARPEADTHGSPLDFHVYDILETVYTHEKCAVIPSDKQGYVVPCGIVIKLLGRRKADGASVCVNVFGQQAYFYASAPQGLDVEFAVLSALKASTFDRRTPCRVSVEKVTRRSIMGYGNHAGDYHKITLSHPNSVCHVATWLQDKHGCRIFEANVDATRRFVLDNDFVTFGWYSCRRAIPRLQHRDSYAELEYDCEVGDLSVRREDSSWPSYQALAFDIECLGEEGFPTATNEADLILQISCVLWSTGEEAGRYRRILLTLGTCEDIEGVEVYEFPSELDMLYAFFQLIRDLSVEIVTGYNVANFDWPYILDRARHIYSINPASLGKIRAGGVCEVRRPHDAGKGFLRANTKVRITGLIPIDMYAVCRDKLSLSDYKLDTVARHLLGAKKEDVHYKEIPRLFAAGPEGRRRLGMYCVQDSALVMDLLNHFVIHVEVAEIAKIAHIPCRRVLDDGQQIRVFSCLLAAAQKENFILPMPSASDRDGYQGATVIQPLSGFYNSPVLVVDFASLYPSIIQAHNLCYSTMITPGEEHRLAGLRPGEDYESFRLTGGVYHFVKKHVHESFLASLLTSWLAKRKAIKKLLAACEDPRQRTILDKQQLAIKCTCNAVYGFTGVANGLFPCLSIAETVTLQGRTMLERAKAFVEALSPANLQALAPSPDAWAPLNPEGQLRVIYGDTDSLFIECRGFSESETLRFAEALAAHTTRSLFVAPISLEAEKTFSCLMLITKKRYVGVLTDGKTLMKGVELVRKTACKFVQTRCRRVLDLVLADARVKEAASLLSHRPFQESFTQGLPVGFLPVIDILNQAYTDLREGRVPMGELCFSTELSRKLSAYKSTQMPHLAVYQKFVERNEELPQIHDRIQYVFVEPKGGVKGARKTEMAEDPAYAERHGVPVAVDHYFDKLLQGAANILQCLFDNNSGAALSVLQNFTARPPF
What is the function of this protein?
Replicates viral genomic DNA in the late phase of lytic infection, producing long concatemeric DNA.  The replication complex is composed of six viral proteins: the DNA polymerase, processivity factor, primase, primase-associated factor, helicase, and ssDNA-binding protein (By similarity).
What are the official names of this protein?
DNA polymerase catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus. Note=the protein is present at discrete sites in nuclei, called replication compartments where viral DNA replication occurs.
Protein: CNNM4_XENTR
Sequence: MAASAGCYYGVLGCALSLLLLPPLSRCAARTDSPLPEELPLILGFRLERSDRHAALSPDGELEVVEGSRLELRVYGLHLREDSGHILAFTEYSPGSQDNRSCLEDSRDLVLTRLNVSDDGFGAAGAAIVRLDVLPLRKSQSSRVYVLCTSRGPGLPWKLHTGPDGRLRVLEEEKPLLPIWLQACIIAVLLTLSGIFSGLNLGLMALDPMELRVVQRCGTEKEKRYASKIEPVRRKGNYLLCSLLLGNVLVNTTLTALLDELIGSGLAAVLASTTGIVVLGEIVPQALCSRHGLAVGANTLWLTRIFMLLTFPVAYPVSRLLDCALGQEIGTVYNREKLLEMLKVTEPYSGIVREEMNIIQGALELRTKTVEDVMTKVEDCFMLPSDAVLDFNTMSSIMESGYTRIPVYENERSNIVDILYVKDLAFVDPDDCTPLSTITRFYSHPLHFVFSDTKLDAVLEEFKKGKSHLAIVQKVNSEGEGDPFYEVMGLVTLEDVIEEIIKSEILDESDLYTDNRSKKRVKRRQDRKDFSVFKDADNELRVKISPQLLLAAHRFLSTEVPLFAPALVSEKTLLRLLKYPDVVQELHFNEDDKKASENFLYQRSKIADYFILILQGKVEVEAGKENMKFESGAFSYYGVMAINTPSAAELRSPSHMSSLNRSISLSCHERSDSISSTISGSNTQLSAQAQYMADFSVRALGDLQFVKITREQYQGALMSSRLDSSPQSPEGGTRKPDSTLSERSEVLEDETTSLLNQRNSQHSLQHNAV
What is the function of this protein?
Probable metal transporter.
What are the official names of this protein?
Metal transporter CNNM4, Ancient conserved domain-containing protein 4, Cyclin-M4.
What is the protein family that this protein belongs to?
Belongs to the ACDP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADD_HERA2
Sequence: MQRVGILGGTFDPIHFAHLAIAEEARVVLGLSQVVFIPTAQQPLKQQHFSSAYQRLAMTKLAIADNPAFSVSTIEVERSGVSYTIDTIQTLHQDQPHIEWWLIVGSDSLATLSRWHAAHDLVQLAHFAILERPGFELDWPALLDQFPELAKRSVRIQGPRMDLSATELRSRLQAGLPVRYLVPDAVASYIAQQQLYLA
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: MBP_RAT
Sequence: MASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFSGDRGAPKRGSGKVPWLKQSRSPLPSHARSRPGLCHMYKDSHTRTTHYGSLPQKSQRTQDENPVVHFFKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQKPGFGYGGRASDYKSAHKGFKGAYDAQGTLSKIFKLGGRDSRSGSPMARR
What is the function of this protein?
Is, with PLP, the most abundant protein component of the myelin membrane in the CNS.  Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers.  Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
What are the official names of this protein?
Myelin basic protein, MBP.
What is the protein family that this protein belongs to?
Belongs to the myelin basic protein family.
What are the subcellular locations of this protein?
Myelin membrane; Peripheral membrane protein; Cytoplasmic side. Note=Cytoplasmic side of myelin.
Protein: CYNS_SYNS3
Sequence: MAAPSPSTLTASLMAAKKAKGLSFADLEVALGLDEVWIASLFYGQATASPEEAEKLATLLGLDPAITAALQEFPTKGSLDPVIPTDPLIYRFYEIMQVYGMPLKDVIQEKFGDGIMSAIDFTLDVDKVEDPKGDRVKVTMCGKFLPYKKW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: SURF4_SCHPO
Sequence: MTSRSPFSTIPLSMNQDSYQTRTTVGIRKKTFSERACQFMEQAETFMAPFTPYMPLLGRFLIVATYFEDAIRIVTQWPEQVSYMRDYRRFRFGTAPLLLFVCVVLMLVGSTLVVFKKRQAYAIGSLLFVTLLQAFAYGLITSGEMFFRNMSVIGGLCLVASDTFIHRRINRFAGLPAVSEHNKRTYFQLAGRVLLIFMFLGLLAKEGSGISWTRILVHILSVTACAMVVIGFKAKFFAAVLVLILSVANFIINSFWSVPRESPYRDFYRYDFFQTLSIVGGLLYLVNTGPGKFSVDEKKKIY
What are the official names of this protein?
Surfeit locus protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SURF4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HDAC1_ORYSJ
Sequence: MDASAGGGGNSLPTAGADGAKRRVCYFYDAEVGNYYYGQGHPMKPHRIRMTHALLAHYGLLDQMQVLKPHPARDRDLCRFHADDYVAFLRSVTPETQQDQIRALKRFNVGEDCPVFDGLYSFCQTYAGGSVGGAVKLNHGHDIAINWAGGLHHAKKCEASGFCYVNDIVLAILELLKYHQRVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKFGDYFPGTGDIRDIGHSKGKYYSLNVPLDDGIDDESYQSLFKPIMGKVMEVFRPGAVVLQCGADSLSGDRLGCFNLSIRGHAECVRFMRSFNVPLLLLGGGGYTIRNVARCWCYETGVALGHELTDKMPPNEYFEYFGPDYTLHVAPSNMENKNTRQQLDDIRSRLLDNLSKLRHAPSVQFQERPPEAELPEQDEDQEDPDERHHADSDVEMDDVKPLDDSGRRSSIQNVRVKRESAETDAADQDGNRVAAENTKGTEPAADGVGSSKQTVPTDASAMAIDEPGSLKVEPDNSNKLQDQPSVHQKT
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (Probable).  Regulates negatively the expression of the NAC48/NAC6 gene that controls root growth in seedlings.  Epigenetically represses the expression of NAC48/NAC6 by deacetylating 'Lys-9' (H3K9ac), 'Lys-14' (H3K14ac) and 'Lys-18' (H3K18ac) of histone H3, and 'Lys-5' (H4K5ac), 'Lys-12' (H4K12ac) and 'Lys-16' (H4K16ac) of histone H4 (PubMed:19453457).  Functions in the regulation of gene expression in the whole genome (PubMed:12581311).  Acts as chromatin remodeling regulator to promote the formation of a repressive chromatin state.  Functions with MODD via its interaction with TPR3, to down-regulates the histone acetylation level at BZIP46 target genes.  BZIP46 is a positive regulator of abscisic acid (ABA) signaling and drought stress tolerance (PubMed:27468891).
What are the official names of this protein?
Histone deacetylase 1, OsHDAC1.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD Type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus.