PharMolix/UniProtQA huggingface dataset:
Protein: DAPEL_BREBN
Sequence: MTTSLFTQIRRDLHQIPEPGFAEVKTQQYLLDYLKKLPQERIEIKTWRTGILVKLAGTKPKRLIAWRTDMDGLPIVEETSYPFRSLHEGYMHACGHDMHMAIALGLLTHFTEHSIADDLLFLFQPAEEGPGGAWPMMESEEFAEWRPDCIFALHIAPEYPVGQIATKPGILFANTSELYIDLVGKGGHAAFPHKANDMVVAGSHLVTQLQSIISRNIDPLDSAVVTIGKLESGTKQNIIAEKSRLEGTIRTFSMESMALVKSRIESLVKGVEIGFDCQATIDYGVGYCQVYNEEQLTTDFMQWVQEQCDDVTLITCKEAMTGEDFGYFLKEIPGFLFWLGVQTPYGLHHSKIEPNEDAIEVAIRLVSRYFTWLSQQE
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: MCMBP_RAT
Sequence: MPCGEDWLSHPLGIVQGFFAQNGVTPDWEKKVIDYFKEKLKENNAPKWVPSLNEVPLHYLKPNSFVKFRCMIQDMFDPEFYMGVYETVNQNTKARVLHFGKYRDVAECGPQQELDLNSPRSTTSERQTFYCVPVPGESLWVKEAYVNANQARVSPSTSYTPSRHKRSYEDDEDMDLQPNKQKDQHSGARQAGGLGGLHWRGEPKRLETEASSGQQLNSLNLSSPFDLNFPLPGEKGPACLVKVYEDWDCFKVNDVLELYGVLSVDPILSILNNEERDASALLDPMECTDMAEEQRVHSPPASLVPRIHVILAQKLQHINPLLPTCLNKEESRTCQFVSNFMSELSPVRAELLGFLTHALLGDSLAAEYLILHLISTVYTRRDVLPLGKFTVNLSGCPQNSTFTEHLYRIIQHLVPASFRLQMTIENMNQLKLIPHKDYTANRLVSGLLQLPNNTSLVIDETLLEQGQLDTPGVHNVAALSNLITWQKVDYDFSYHQMEFPCNINVLITSEGRSLLPADCQIHLQPQLIPPNMEEYMNGLLSAVLPSVLNKFRIYLTLLRFLDYNLSDDITKAVEDDFVEMRKNDPQSITADDLHQLLVVARFLSLSAGQTTLSRERWLRAKQLEHSRRSRLQQQKSVNGNEL
What is the function of this protein?
Associated component of the MCM complex that acts as a regulator of DNA replication.  Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA.  Can dissociate the MCM complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex.  Required for sister chromatid cohesion (By similarity).
What are the official names of this protein?
Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MCMBP family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin. Highly associated with chromatin in G1/S and S phases, reduced binding to chromatin in G2, and further decreased binding in early M phase. It then reassociates with chromatin in late M phase. Dissociates from chromatin later than component of the MCM complex (By similarity).
Protein: MSHC1_CORJK
Sequence: MHAWPDPSVPVVAGTPVPLKLFDTADQRVKEVDTTPDANGEVGMYVCGITPYDSTHLGHAATYLTFDLAQRQLLANGHKVHYAQNITDVDDPLFERAERDGVDWRELGTSQINLFRSDMEILSVIPPRDYIGAMESVDEVIAMVQQLLDAGAAYELDQGDIYASIDATEQFGYESNLDRATMEEYFAERGGDPDREGKRDPLDALIWRGHREGEPAWDSPFGPGRPGWHVECSAIATNRLGSHFAIQGGGSDLAFPHHEFSAAHAEAALKVERMAGHYVHAGMIALDGVKMSKSLGNLVFVHKLSEAGHDPSAIRLAVFAGHYREDRDFSDAILAEAEERLTRWREQLAGEVSEAEATEVVDKLRAILADDLNTPEALSLLDGAAGDCNQIIATALDGLLGVRI
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 1, L-Cys:GlcN-Ins ligase 1, Mycothiol ligase 1, MSH ligase 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: DER_MYCGA
Sequence: MLKVAIVGKPNVGKSTLFNRLIKNRIAIVDDTPGITRDRIFGDVEWLTKRFQIIDTGGLTTESDVFQRAIEQQVQFAIDEADIILFVCSYKEGINADDHYAAKLLKKHKNKKIIFVLNKIENQNKDQLNLSSYFSLGFGKPMIISAEHAIGIGDLLDEIIGLKDQFGNKKEQELVATFCIIGKPNVGKSSLLNQLLKKERVLVSDIPGTTRDAIDATFSYNKELYKVIDTAGIRRKGKIATRIEKFSVQRTQQAISRSKMILLMLDGSVDLSEQDEVIGGLCYEANLPTIIVVNKWDLVKKDDKTMELFKKQIRSKFKYLPWSPIIFISAKANLRIDTIFQTIKLIQAQLKIKISTSLLNDVVQKAHMINQPPIFNGNRLSITYTTQAQGQIPTFVLFCNNPDYLHFSYARYLENKIREAFGLSYVPITLYFKSKNARNRKLSKDVKFKQTGYDLE
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PTH_CHLCH
Sequence: MKLIIGLGNPGTEYDGTRHNIGFAVADALAAHHNASFSKEKGRYLSAKIKLGSESVGIIKPMTYMNHSGHAVVAAMNFYKVARTEIVVICDDLNLPVGTMRLRPKGSAGGQNGLKHIIECFGSNEFARLRIGIGSQNMPKGGFSSFVLGKFSEQEKSEIAIMTVSARDCAIDFALHGLGHAMNHFNTSKL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHBI_BACSU
Sequence: MTESERALLTFEQLFDTSRAIYKKQKKILEIVLEPFDITVLQYLLMFKIHQSGSTPLSKLAMSLDLKPASVTRMTDILYKRQLMNRYDSPDDRRIVMIQLTEEGEELIEKAAVQYAKMGAGLYQKLDTSQLQYLRKLAGSLTKLAEGCSEKSGN
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YhbI.
Protein: NUSB_MYCVP
Sequence: MPDRKGDRGRHQARKRAVDLLFEAEARGITAAEVAEARNALAEKRTDDIATLNPYTVTVAQGVTAHAAHIDDLISAHLQGWTLDRLPAVDRAILRVAVWELLHAEDVPEPVAVDEAVELAKQLSTDDSPGFVNGVLGQVMLVTPQIRAAAAAMQGGHNGGSGT
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: ALDR_RAT
Sequence: MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCALMSCAKHKDYPFHAEV
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and xenobiotics substrates.  Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia.  Reduces steroids and their derivatives and prostaglandins.  Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal.  Catalyzes the reduction of diverse phospholipid aldehydes such as 1-palmitoyl-2-(5-oxovaleroyl)-sn -glycero-3-phosphoethanolamin (POVPC) and related phospholipid aldehydes that are generated from the oxydation of phosphotidylcholine and phosphatdyleethanolamides.  Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls).
What are the official names of this protein?
Aldo-keto reductase family 1 member B1, Aldehyde reductase, Aldose reductase, AR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_CERS4
Sequence: MTLILGSASPRRRELLAQLGVTPDAILPPDIDEEPRRGELPRPYCARLAAEKAAAVAAGPEDVVLCADTTVALGRRILGKPADAGEAARFLVALGGRRHEVITAVAVRRGDRLWQREVVSQVKMKRLSDLELNAYLASGEWEGKAGGYAIQGLASAFIPWISGSFTGIVGLPLAETATLLAAAGVPLYRAAA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y037_MYCTU
Sequence: MPRVEVGLVIHSRMHARAPVDVWRSVRSLPDFWRLLQVRVASQFGDGLFQAGLAGALLFNPDRAADPMAIAGAFAVLFLPYSLLGPFAGALMDRWDRRWVLVGANTGRLALIAGVGTILAVGAGDVPLLVGALVANGLARFVASGLSAALPHVVPREQVVTMNSVAIASGAVSAFLGANFMLLPRWLLGSGDEGASAIVFLVAIPVSIALLWSLRFGPRVLGPDDTERAIHGSAVYAVVTGWLHGARTVVQLPTVAAGLSGLAAHRMVVGINSLLILLLVRHVTARAVGGLGTALLFFAATGLGAFLANVLTPTAIRRWGRYATANGALAAAATIQVAAAGLLVPVMVVCGFLLGVAGQVVKLCADSAMQMDVDDALRGHVFAVQDALFWVSYILSITVAAALIPEHGHAPVFVLFGSAIYLAGLVVHTIVGRRGQPVIGR
What are the official names of this protein?
Uncharacterized MFS-type transporter Rv0037c.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS7_BREBN
Sequence: MPRKGPVTRRDVLPDPIHNSKLVTRLINRLMLDGKRGVAQNILYNAFDIIQERTGRNPMEVFEEALKNVMPVLEVKARRVGGANYQVPIEVKPERRTTLGLRWMVNYSRNRGEKTMEQRLANEIMDAANNTGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HIS7_BACAH
Sequence: MRESSQIRETTETKIKLSLQLDEGKNVSVQTGVGFFDHMLTLFARHGRFGLQVEAEGDVFVDAHHTVEDVGIVLGNCLKEALQNKEGINRYGSAYVPMDESLGFVAIDISGRSYIVFQGELTNPKLGDFDTELTEEFFRAVAHTANITLHARILYGSNTHHKIEALFKAFGRALREAVERNAHITGVNSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOY_STAA8
Sequence: MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFNIEFITKLEGAHLDYEKENSEHFNVEIAK
What is the function of this protein?
A non-essential component of RNA polymerase (RNAP).
What are the official names of this protein?
DNA-directed RNA polymerase subunit epsilon, RNAP epsilon subunit, RNA polymerase epsilon subunit, Transcriptase subunit epsilon.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit epsilon family.
Protein: ARGB_COLP3
Sequence: MNNPVLKPLVIKIGGAILEKESALNALLNVISQLKNKQVVLVHGGGCVVDEMLAQAGFTTEKKHGLRVTPKEQVGLISGALAGTVNKAIVGTANSMDLAAVGLSLNDGDMISCTLSTQDLGQVGVPQTNNSKLLDCLLKAKFLPVISSIGALDNGDLVNVNADDAAVAICQLLNAELLLLTDVNGVKDADGEYLSSLNAEQAQKLIEQGVIAGGMTAKVNAALHAAQQLRRSIAVASWQSPEQITQLLDGHGVGTQIQPN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUF6_YEAST
Sequence: MAPLTKKTNGKRSAKEVSHSEKKLAKKPRISIDSSDEESELSKKEDAVSSSSDDDDLDDLSTSDSEAEEEADELDISDDSEEHENENEEKEGKDKSEGGENGNHTEQRKLLKERKMQRKSGTQVQQIKSVWERLRVKTPPLPKQIREKLSNEIWELSKDCISDLVLKHDASRIVQTLVKYSSKDRREQIVDALKGKFYVLATSAYGKYLLVKLLHYGSRSSRQTIINELHGSLRKLMRHREGAYVVEDLFVLYATHEQRQQMIKEFWGSEYAVFRETHKDLTIEKVCESSIEKRNIIARNLIGTITASVEKGSTGFQILHAAMREYVKIANEKEISEMIELLHEQFAELVHTPEGSDVACTLVARANAKERKLILKALKNHAEKLIKNEYGNIVFITILNCVDDTVLVFKTFSPTVKEHLQEFIIDKFGRRPWLYILLGLDGKYFSPIVKNELLRYIELSKATSKKDPLQRRHELLSKFAPMFLSTISKDYSSILTENLGCQFIAEVLINDELYAQLNEKDQEKYQQVLNNILTTFKGDITEEEHPIHRAFSTRLLKALIQGGKWNNKEKKVIPLKNVQGLGVPFAEKLYDEIIDSSNLLEWINNADSSFTIVALYETLKDQKEGKPFLKDLRGVQSKITTDESNKGSQLLAKLLK
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation.  Component of the ASH1 mRNP which transports the ASH1 mRNA to the distal tip of the bud, where the ASH1 protein is translated and targeted to the daughter cell nucleus.  Binds to the ASH1 3'-UTR containing the PUF consensus UUGU segment and represses its translation.  This silencing of ASH1 mRNA is critical for asymmetric seggregation of ASH1 to the daughter cell nucleus.
What are the official names of this protein?
Pumilio homology domain family member 6.
What is the protein family that this protein belongs to?
Belongs to the PUF6 family.
What are the subcellular locations of this protein?
Bud tip. Nucleus, nucleolus.
Protein: Y315_CITK8
Sequence: MDWLAKYWWILVLVFLVGVLINVIKDLKRVDHKKFLANKPELPPHRDFNDKWDDDDDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein CKO_00315.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: TRPC_RHOBA
Sequence: MTILDDILVKTRQVIARDQASVPAAELVAAAKDLPVCRDFHGSLAATDQVRLIAEVKRASPSAGLIREDFDPPTIAKSYEDGGAACISVLTDEPFFQGSLDYLRQVRSAVDLPILRKDFIVDPYQLLQARVAGADAVLLIAECLSPQQLIEMDEQASELGLQTLIELYEPENLAPVLATKTRLVGINNRDLRTFETDLQHCVRLAADIPSDRLVVGESGIRTAADVAMLKAGGIKAILVGESLMRQPDITIATKALLAS
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: SAND_LEWP2
Sequence: MTTPSFIPSVNFHLIKPCNMGCKYCFARFNDVASKSLTRGGLPKEDALAVVSALADFGFEKITFAGGEPTLYPWLTDVIELAKNKGMTTMLVTNGSRLNEAFYLRHAGLLDWITVSIDSLSVGTNLAIGRAKHGNQVFAREDYEVIAAMIHDYSYRLKINTVVSRYNHEEDMNDFIAHAKPERWKVFQALPIVGENDEYLEEFEITAEEFQQFLGRHGSQAKLVKENNDEMRGSYAMVDPKGCFFTNVNGQLEASSPILTVGCDAALREMNYDLTKFHDRGGRYDW
What is the function of this protein?
Expression of pVip21 in E. coli (strain MG1655) confers resistance to phage T7; prevents culture collapse upon infection.  Catalyzes the conversion of guanosine triphosphate (GTP) to 3'-deoxy-3',4'-didehydro-GTP (ddhGTP), probably via a SAM-dependent radical mechanism.  Overexpression of this protein is not toxic in E. coli, thus modified nucleotides do not affect bacterial transcription machinery (PubMed:32937646).  The modified nucleotide represses transcription from T7 RNA polymerase-directed genes (possibly by acting as chain terminators), strongly suggesting these nucleotides block viral polymerase transcription (By similarity).
What are the official names of this protein?
S-adenosylmethionine-dependent nucleotide dehydratase, SAND, Prokaryotic viperin protein pVip21, pVip21.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Viperin family.
Protein: GSA_HELPG
Sequence: MELLHSINDFNEAKQVIAGGVNSPVRAFKSVKGTPPFILKGKGAYLYDVDNNHYIDFVQSWGPLIFGHADEEIEKNIINTLKKGTSFGAPTELETTLAKEIVSCYEGLDKVRLVNSGTEATMSAIRLARAYSQKDDLIKFEGCYHGHSDSLLVKAGSGCATFGSPSSLGVPNDFSKHTLVARYNDLNSTEECFKKGDVGCVIIEPIAGNMGLVPAQKEFLLGLKALCEKYQAVLILDEVMSGFRASLSGSQEFYGVVPDLVTFGKVIGAGLPLACFGGRAEIMDLLSPIGGVYQAGTLSGNPLAVCAGLSALYKIKRDKTLYTRLNALAVRLTQGLKKSAQNYNIALETLNMGSMFGFFFNENAVCDFDDALKSDTEMFAKFHQKMLFKGVYLACSSFETGFICEPMTEEMIDLAVAKADESFDEIIKGV
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_ALKCK
Sequence: MKRIGLFGGTFDPPHLGHLLIAQEALTAVKLDEVWFVPVSTPPHKERAGLTSGKDRYDMVKAALVQEERFRVCDIELIRKGKSYTIDTVRELKQTYPDDEFFFLIGGDMVNMLPEWRGIDELKQLVTFVAFNRPGASAKSQPDVHFVPFVEVNISSSLIRERLAKGKPIRYFVTPAVEQLIEERNLYGDNNE
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: PSAD_THEVB
Sequence: MTTLTGQPPLYGGSTGGLLSAADTEEKYAITWTSPKEQVFEMPTAGAAVMREGENLVYFARKEQCLALAAQQLRPRKINDYKIYRIFPDGETVLIHPKDGVFPEKVNKGREAVNSVPRSIGQNPNPSQLKFTGKKPYDP
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.
What are the official names of this protein?
Photosystem I reaction center subunit II, Photosystem I 16 kDa polypeptide, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
Protein: YG41_SCHPO
Sequence: MSSSPTESEILPKESHNSIDEQSQQPANTDTLVKDNSFNEQDDQEVDNDYKSNDEPVQSQDPISPNMASNESGNSENTSNYGSSRDENVYQKTTLWMGELEPWVTEAFIQQVWNTLGKAVKVKLIRNRYTGMNAGYCFVEFASPHEASSAMSMNNKPIPGTNHLFKLNWASGGGLREKSISKASEYSIFVGDLSPNVNEFDVYSLFASRYNSCKSAKIMTDPQTNVSRGYGFVRFTDENDQKSALAEMQGQICGDRPIRVGLATPKSKAHVFSPVNVVPVSMPPVGFYSAAQPVPQFADTANSTVFVGGLSKFVSEEELKYLFQNFGEIVYVKIPPGKGCGFVQFVNRQSAEIAINQLQGYPLGNSRIRLSWGRNQNPIAAPALNYQSQVSQTTIPATSLFPAMSLPPQAQFSPYPAVAPSPLALQTRGAPIGMEISIGSPALVPDQMHIPENGNSDTMPVPNTQGKHLSAEE
What are the official names of this protein?
Uncharacterized RNA-binding protein C23E6.01c.
Protein: RAE1L_HUMAN
Sequence: MSLFGTTSGFGTSGTSMFGSATTDNHNPMKDIEVTSSPDDSIGCLSFSPPTLPGNFLIAGSWANDVRCWEVQDSGQTIPKAQQMHTGPVLDVCWSDDGSKVFTASCDKTAKMWDLSSNQAIQIAQHDAPVKTIHWIKAPNYSCVMTGSWDKTLKFWDTRSSNPMMVLQLPERCYCADVIYPMAVVATAERGLIVYQLENQPSEFRRIESPLKHQHRCVAIFKDKQNKPTGFALGSIEGRVAIHYINPPNPAKDNFTFKCHRSNGTNTSAPQDIYAVNGIAFHPVHGTLATVGSDGRFSFWDKDARTKLKTSEQLDQPISACCFNHNGNIFAYASSYDWSKGHEFYNPQKKNYIFLRNAAEELKPRNKK
What is the function of this protein?
Acts as mRNA export factor involved in nucleocytoplasmic transport (PubMed:33849972, PubMed:20498086).  Plays a role in mitotic bipolar spindle formation (PubMed:17172455).  May function in attaching cytoplasmic mRNPs to the cytoskeleton both directly or indirectly (PubMed:17172455).
What are the official names of this protein?
mRNA export factor RAE1, Rae1 protein homolog, mRNA-associated protein mrnp 41.
What is the protein family that this protein belongs to?
Belongs to the WD repeat rae1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Nucleus envelope. Note=Recruited from interphase nuclei to spindle MTs during mitosis.
Protein: HTPG_CHLL3
Sequence: MSNKQNTAVQEFEYKAEMKQLLDLIVHSLYTHPEIFLRELVSNASDALSKARFSALTDDTMAKVSGEAAIRISLDAKTAAFAIEDTGIGMTEEELIANLGTVARSGTLGFMQALRQEKKELDGNLIGQFGVGFYSVFMVTDDVTVETRSARAGSEGLRWRSSGQGTYTIEKIDKKEPGTRISFTLKDEHKEFAEEYRVEHIIKKYSNFVDFPIYLETKQLNSITALWQRPKSELKQEEVNEFYKFISNDFNEPLDYLHVSVEGAVSFKAILFLPKEAPMELLYRQGELENKGPQLYVKKVMIQHECRDLLPEYLRFIAGVVDTEDLSLNVSREIVQSSPVMSKIRQILTGKILGWFEELATAQPEKFRTFYKAFGPIVKIGLNTDFTNRDKLIELLRFESTKTGEGEYVTLKEYAARMAPDQKEIYYHSGAGRAQLLANPNLEYFQDKGIEVLLLSDPVDVFVIPSIHEYDKKQLKSIEKADIDFSKATKDKTEPIAENLLVPLLKIFRETLGEGIEDVVESHRLVSSPVTLVSGKDAMDSQMERMMKMMQQEMPAGRKILEVNPSHPIIRNLSGMMMANDNNPLIRTAIHQLYEGALLLEGGLDSTTGFVSRMNELIEAATLSR
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3L22_BUNCA
Sequence: YTLLCYKTPIPINAETCPPGENLCYTKMWCDIWCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPD
What is the function of this protein?
Binds to muscular and neuronal nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission (PubMed:30944155).  Blocks muscle type nAChR (PubMed:30944155).  Also binds with high affinity to alpha-7/CHRNA7 nAChRs (By similarity).  In addition, shows a weak inhibition of neuronal alpha-3-beta-2/CHRNA3-CHRNB2 nAChR (By similarity).  Selectively binds to alpha-1-delta subunit interface of the mouse muscle nicotinic acetylcholine receptor, with a 10-fold higher affinity for the adult than for the fetal receptors (By similarity).  In vivo, when intraperitoneally injected into mice, causes flaccid paralysis and respiratory distress, followed by death within 2-4 hours (By similarity).
What are the official names of this protein?
Alpha-elapitoxin-Bc2b, Alpha-EPTX-Bc2b, Alpha-delta-Bgt-2, Alpha/delta-bungarotoxin-2, Alpha/delta-BgTx-2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SOPA_ECO57
Sequence: MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGEAADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAEDVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDLHIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPTDPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRETDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR
What is the function of this protein?
This protein is essential for plasmid partition.  It ensures the proper distribution of newly replicated plasmids to daughter cells during cell division.  SopA is trans-acting (By similarity).
What are the official names of this protein?
Protein SopA, Plasmid partition protein A.
What is the protein family that this protein belongs to?
Belongs to the ParA family.
Protein: RL1_KINRD
Sequence: MKRSKSYRAAAEKIDFEELYAPLDAVKLARETSTVKYDATVEVAFRLGVDPRKADQMVRGTVNLPHGTGKTARVLVFAVGDRAAQAEAAGADIVGGDELIDEVAKGRLDFDAAVATPDLMGKVGRLGKVLGPRGLMPNPKTGTVTMDVAKAVSEIKGGKIEFRTDKHANLHFVIGKASFDDTQLVENYSAALDEVLRLKPSSSKGRYLKKATITTTMGPGVPVDPTLTRNLTGEATAV
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RIHA_ECOBW
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTSVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: RS3_SYNAS
Sequence: MGQKVNPIGLRLGINKNWNSRWYADKSYRSMLYEDLKIRGYLKKKLYHAGISHIDIERAVNKAKVNIYAARPGIIIGKKGAEIEKLKKELENVSSSEIIINILEVRKPEIDAQLVAENIATQLERRVAFRRAMKKCVLTALKFGAKGIRVSCSGRLGGAEMSRTEWYREGRVPLHTLRADIDSGFTEAKTAYGQIGIKVLIFHGEVLPGRKELEKP
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: TRHB_XENLA
Sequence: MMFLWWLLLLGTAISHKVHSQEQPLLEEDTAPADNLDVLEKAKGILIRSFLEGFQEGQQINRDLPDAMEMIYKRQHPGKRFQEEIEKRQHPGKRDLEDLQLSKRQHPGRRYLEDMEKRQHPGKREEGDWSRGYLTDDSGYLDLFSDVSKRQHPGKRVPDPFFIKRQHPGKRGIEEEDDTEFENSKEVGKRQHPGKRYDPCEGPNAYNCNSGNLQLDSVEEGWAA
What are the official names of this protein?
Pro-thyrotropin-releasing hormone-B, Pro-TRH-B, Prothyroliberin type B.
What is the protein family that this protein belongs to?
Belongs to the TRH family.
What are the subcellular locations of this protein?
Secreted.