PharMolix/UniProtQA huggingface dataset:
Protein: RL1_THET2
Sequence: MPKHGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGIDPRRSDQNVRGTVSLPHGLGKQVRVLAIAKGEKIKEAEEAGADYVGGEEIIQKILDGWMDFDAVVATPDVMGAVGSKLGRILGPRGLLPNPKAGTVGFNIGEIIREIKAGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRAFIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: NUSB_BACVZ
Sequence: MKRRTAREKALQALFQIDVSDIAPNDAIEHALDGEKTDAFFEQLVYGVIEHQVQLDEMISGHLVNWKLDRIANVDRAILRLAVYEMVYSDDIPANVSLNEAIELAKRFGDDKAAKFVNGVLSNIKTDIES
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: CBG_MOUSE
Sequence: MSLALYTCLFWLCTSGLWTTQAVTDEDSSSHRDLAPTNVDFAFNLYKRLVALNSDKNTLISPVSISMALAMLSLSTRGSTQYLENLGFNMSKMSEAEIHQGFQYLNSLLQQSDTGLEMNMGNVMFLLQNLKLKDSFLADTKHYYESEALTIPSKDWTKAGEQINNHVKNKTQGKIEHVVSDLDSSATLILINYIFLKGIWKLPFSPENTREEDFYVNETSTVKVPMMVQSGNISYFRDSAIPCQMVQMNYVGNGTTFIILPDQGQMDTVVAALNRDTIDRWGKLMIPRQMNLYIPKFSMSDTYDLQDVLADVGIKDLFTNQSDFADTTKDTPLTLTVLHKAMLQLDEGNVLPAATNGPPVHLPSESFTLKYNRPFIFLAFDKYTWSSLMMSQVMNPA
What is the function of this protein?
Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species.
What are the official names of this protein?
Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PI_BURCJ
Sequence: MTLKSLPAWTALQSHFEQIRHARLRDWFAPENDRAPTRAERFTIPGGGLAADFSKNRIDDETVRLLVQLARDAGVEARRDAMFAGEIVNPTEGRAALHTALRATDPQAPFHAQVSAERAKMATFARAVRSGTWTGYTGKRIRHVINIGIGGSDLGPKMVVHALHHVATPEISTHFVSNVDGADLARVLEQVDPEETLAIIVSKTFTTLETMTNARSLRDWFVARGCPEDALAKHFVGVSANPAEVVKFGIAADNVFEMWDWVGGRYSLWSAVGLSIMIAVGPEQFDELLAGANDMDRHFREAPLERNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHYLPSYLQQLEMESNGKSARLDGTFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLTPEHPLASHHPKLLANCFAQSEALMLGRTLEEARKVAGPGKEALAPHLTFPGNRPTTTLLVDALTPRALGALIALYEHKVLVQATVWDINPFDQWGVELGKILGKVVEADLSAESVDPAKHDSSTTALIERARAALKR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_YERPE
Sequence: MTKKKAYKPGSATIAQNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVMFKNGEAFLFGATITPLNVASTHVVCEPMRTRKLLLNKRELDSLFGRVNREGYTVVALSMYWKNAWVKVKIGVAKGKKDNDKRDDIRDREWKLDKARIMKHANR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PKG16_BPB03
Sequence: MLSYDRILNFVIGARGIGKSYAMKKHPIKRFIKHGEQFIYVRRYKPELKKIGNYFNDIAQEFPNHEFKVKGRQFCIDGKLTGWAIPLSAWQSEKSNAYPMVTTIIFDEFIRERDNSGYIPNEVDALLNLMDTVFRTRENGRCICLSNAVSIINPYFVYFGLVPDINKRFNAYKHILIEIPDSKDFSDERRKTKFGQLIDGTEYGEMSLDNEFVNDSDVFIEKRSKNSKFVFSIVYKGMRMGVWVDTQQMLLYLTTDHDPSTKNVYALTADDLEEGMILVSNYKKNYHIRKLCSAFMNGQLRFDNQLMRTIGYEMFKKMRVQ
What is the function of this protein?
ATPase required for the genome encapsidation reaction.  Part of the active packaging motor via the binding to the packaging RNA (pRNA), itself fixed to the head-tail connector at the unique portal vertex of the prohead.  Binds and supercoils the DNA-gp3 to produce an initiation complex for DNA packaging.  Provides the energy to actively pump the viral DNA into the prohead.  Approximately one molecule of ATP is used in the packaging of 2 bp of viral DNA.  After packaging, the ATPase and the pRNA are released from the prohead.
What are the official names of this protein?
DNA packaging protein, ATPase gp16, Gene product 16, gp16, Protein p16.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus gp16 family.
Protein: NANE_STAAM
Sequence: MLPHGLIVSCQALADEPLHSSFIMSKMALAAYEGGAVGIRANTKEDILAIKETVDLPVIGIVKRDYDHSDVFITATSKEVDELIESQCEVIALDATLQQRPKETLDELVSYIRTHAPNVEIMADIATVEEAKNAARLGFDYIGTTLHGYTSYTQGQLLYQNDFQFLKDVLQSVDAKVIAEGNVITPDMYKRVMDLGVHCSVVGGAITRPKEITKRFVQVMED
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: CAPSD_HEVMG
Sequence: MRPRAVLLLLFVLLPMLPAPPAGQPSGRRRGRRNGGAGGGFWGDRVDSQPFALPYIHPTNPFAADVVSQPGAGARPRQPPRPLGSAWRDQSQRPSTAPRRRSAPAGAAPLTAVSPAPDTAPVPDVDSRGAILRRQYNLSTSPLTSSVAAGTNLVLYAAPLNPLLPLQDGTNTHIMATEASNYAQYRVVRATIRYRPLVPNAVGGYAISISFWPQTTTTPTSVDMNSITSTDVRILVQPGIASELVIPSERLHYRNQGWRSVETTGVAEEEATSGLVMLCIHGSPVNSYTNTPYTGALGLLDFALELEFRNLTPGNTNTRVSRYTSTARHRLRRGADGTAELTTTAATRFMKDLHFTGTNGVGEVGRGIALTLFNLADTLLGGLPTELISSAGGQLFYSRPVVSANGEPTVKLYTSVENAQQDKGITIPHDIDLGDSRVVIQDYDNQHEQDRPTPSPAPSRPFSVLRANDVLWLSLTAAEYDQTTYGSSTNPMYVSDTVTLVNVATGAQAVARSLDWSKVTLDGRPLTTIQQYSKTFYVLPLRGKLSFWEAGTTKAGYPYNYNTTASDQILIENAAGHRVAISTYTTSLGAGPTSISAVGVLAPHSALAVLEDTVDYPARAHTFDDFCPECRTLGLQGCAFQSTIAELQRLKMKVGKTRES
What is the function of this protein?
Forms an icosahedral capsid with a T=1 symmetry and a 34 nm diameter.  The capsid is composed of 60 copies linked to each other.  Binds to the 5' end of the genomic RNA to mediate genome encapsidation (By similarity).  Binds to heparin surface proteoglycans (HSPGs) to mediate viral entry.  Additionally, the interactions with host ASGR1 and ASGR2 facilitate viral infection of hepatocytes (By similarity).  Inhibits IFN production by blocking host TBK1-induced IRF3 phosphorylation (By similarity).  The nuclear form probably modulates host gene expression (By similarity).
What are the official names of this protein?
Pro-secreted protein ORF2, Protein ORF2, pORF2.
What is the protein family that this protein belongs to?
Belongs to the hepevirus capsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host cell surface. Note=Initially cotranslationally translocated into the ER from where it is retrotranslocated to the cytoplasm. A fraction is also observed on the cell surface (By similarity).
Protein: FRBC_STRR3
Sequence: MRNDLVLEDTTLRDGEQTPGVAFSKETKTAILNALIEAGVTSIEIGIPAMGGEELDFIKSVVDRQDEARLVVWHRGVREDVERSLDLGFTSVHVGLPTSAGHLKASVRKDRTWLLATARDMVKMAKDRGAFVSISAEDIARTEISFLQEYAGVVAEAGADRLRLSDTVGLLGPEAYGERVAAVLSAADIDVQCHAHNDFGLATANTLAGLKAGARYFHVTVNAIGERAGMADLAQVVVALKKLYDRDLGIDLTKLKKVSRLVAEAAGHQVLPWQPITGDNVFAHESGIHANGMFRDTSSFEPFPPEHVGGERRYVLGKHSGRALVAWALEQEGITPREELLPHCLEEVRALSIRIGGAVSHEQLVEIYNKAAA
What is the function of this protein?
Involved in the biosynthesis of the phosphonic acid antibiotic FR900098, a potential anti-malarial drug, which acts as a potent inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), the first enzyme in the nonmevalonate pathway for isoprenoid biosynthesis.  Catalyzes the condensation between acetyl-CoA and phosphonopyruvate to yield (R)-2-(phosphonomethyl)malate.
What are the official names of this protein?
2-phosphonomethylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family.
Protein: CINA_CLOBJ
Sequence: MKAEILCVGTELLLGDIVNTNAQYISKELANIGIEVYHHSVIGDNENRLLKELERAFNYCDLVITTGGLGPTKDDLTKESVAKFFQEDLVLHEKSLKQIEKRLLCFNKSMTESNRKQAYFPKNCEILENPNGTAPGFIIEKDNKIAIILPGPPYEMQPMFENKVIPYLEKLTNSTIKSKVLRITGIGESDVADLISDILERQTNPTVAPYAKQGETTLRITAKANSEEKAISLIVPIEKKIRQILGDNIYSSGETLLEEVVANILVKRNLTIATAESCTGGLLAGKLINFPGISSVFLEGAITYSNESKINRLNVKKETLEKYTAVSKEVALEMAEGIAKSAGTNIGISTTGVAGPGGGTYDKPIGLIYIGLYINGKTFVKELNYSGNRQFIRNITVTRALDFLRRNLK
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: NUON_COXBU
Sequence: MPSELPNFIPAVPEMFVLFMALVILLAGVFIKKRHQIPYYLTQITLILVAGLTWYIFTYSDFAETSFTFHHMFVLDRFSVYLKLFIYLSVFFAFIYAREYNDERKIPHTEFYVLGLLSMLGMVALVSSSNLLTVFLGLELLSLPTYAMVALYRNKTRSVEAGMKYFVIGAIASGMLLYGMSMIFGATQSLDLTEIAKAVSATPLHQNLILVFGLVFIVAGVAFKLGTAPFHMWVPDVYEGAPSSVTLFISTAPKIAAYAMIIRLLILGMPALHVQWHQMLIVVAILSMGIGNFAAIVQSNIKRMLAYSSIAHMGYMLLGVLCGTRNGYAAAMFYTITYSLMSLGAFGMVVLMSRGGFEAENINDFAGLNSRNPWLAFMMMLILFSLAGVPPLVGFIAKVGVLDALIQVHLVWLAVLAVLFAIVGAYYYIRVVKVMYFESAPPQLKPIRCSLEMKIAISLNGLAVLFIGIFPGWLYALSHLAF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DER_BACP2
Sequence: MGKPVVAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYSSAEWLNYDFNLIDTGGIDIGDEPFLAQIRHQAEIAMDEADVIIFMVNGRDGVTSADEEVAKILYRTKKPVVLAVNKLDNPEMRSDVYDFYALGFGEPYPISGTHGLGLGDLLDAVAEHFKNLPDTQYDEQVVQFCLIGRPNVGKSSLVNAMLGEDRVIVSNIAGTTRDAVDTMFAYNQRDFVIVDTAGMRKKGKVYETTEKYSVLRALKAIDRSDVVAVVLDGEEGIIEQDKRIAGYAHEAGKAVVIVVNKWDAVEKDERTMKEFEQNIREHFQFLDYAPVLFMSALTKKRIHTLMPSIITASENHAMRVQTNILNDIIMDAVAMNPTPTHNGQRLKIYYATQVAIKPPSFVVFVNDPELMHFSYERFLENRIRDAFGFEGTPIKIFARARK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: KDM7A_DANRE
Sequence: MAAAPLYCVCRQPYDVNRFMIECDICKDWFHGSCVQVVEHHAADIDVYHCPNCEPIHGPYMMKKHNNWHRHDYTEPNDGTRPVQAGTAVFVKELQARSFASGDILVQMQGNQVTKRFLEKEGFNYPIVVHDLDGLGLKLPPPSFSVSDVEHYVGANKVIDVIDVAKQADSKMKLGEFVKYYYQPERPKVLNVISLEFSDTRMSNLVVVPDIAQKMSWVENYWPDDSFFPKPFVQKYCLMGMKNSYTDFHIDFGGTSVWYHVLWGEKIFYLIKPTKANLALYEAWSSSPNQSEVFFGEKVDKCYKCVVKQGTTILLPTGWIHAVLTSQDSMAFGGNFLHNLNIDMQLRCYEMERRLKTPDLFKFPYFEAICWYVAKNLLETLKELRENKCEAQGFLVNGVKALISSLKMWLRRELTQPNSEVPDNIRPGHLIKALSKEIRHLEDDSNKAVKTQGSAECSLSRSTLEKGDQAQQAARRLQDHHHHRRRHHHHHHHHHHHHHHHHSRKLPSNLDVLELHTLEVLKRLEVGQLKEDSAFSSKVNGKFKKVCPVPAAAVEASHDNALRLVMCNGKIIRERMPITNVAATVNAVEMYHKHRIKLERIPMCPEEKVKKEKCEDEFGVQCTIKKPVSQGESVQTELRTESPHLASSDSDSKAGDSAEKCSLESESSDGEDGGSQRDSGTFVEHLNSHRHSHHKQALKRERPTSPNTDCAIQGMLSMAGLLCPQASGGAADILQQRWWASQGNGSSTSSSSDMWDSSEPCSAPRSPDAEDGSLGEEYSYRESSLSPPLHPSKRHAPNPTPVSNQATKGKRPKKGQATAKQRLGKILKMSRHKGLFLMKPMVFLIPQQGGTPLDPQFLLQSSSICVFPPPLIVSG
What is the function of this protein?
Histone demethylase required for brain development.  Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 7A, DrKDM7a, JmjC domain-containing histone demethylation protein 1D-A.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family. JHDM1D subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1862_STRP1
Sequence: MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQDLVTATFTGDKKLVGIDFKEAVVDPEDVETLQDMTTQAINDALTQIDETTKKTLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SPy_1862/M5005_Spy1580.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NSE1_XENTR
Sequence: MAEQINESHQRFLQVLMSHGIMESSLVRALHRHCCEVHKVNYMHDNLDDFVGVLNKHLQPLFMKIEKGVGEEDGLTYYALVNRVENDITKMASDYAENELELFRKTMELIIISENGFAPPISILNLADELQSKKMKKKEVEQLLQSFVQDKWLIGRNGEYTLHTRCIMELEHYILNTYQDVAKICNVCHKIAIQCQLCENCGIPLHLQCAGIYFRGIANPLCPNCKESWPHEIPDLSQVSSQGPSHSQAAPVRGRNQRSRNISTVARTSR
What is the function of this protein?
RING-type zinc finger-containing E3 ubiquitin ligase that assembles with melanoma antigen protein (MAGE) to catalyze the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate.  Within MAGE-RING ubiquitin ligase complex, MAGE stimulates and specifies ubiquitin ligase activity likely through recruitment and/or stabilization of the E2 ubiquitin-conjugating enzyme at the E3:substrate complex.  Involved in maintenance of genome integrity, DNA damage response and DNA repair.
What are the official names of this protein?
Non-structural maintenance of chromosomes element 1 homolog, Non-SMC element 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NSE1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: GCSH_SALTY
Sequence: MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYTGGWIFKIKASDESELESLLDATAYEALLEDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: PROA_MYCSK
Sequence: MSVHAPAAPDLRTEVHDAARRARVASRTLATLSTETKNRALRAAADRVLMDAHLIIAGNERDLEKARAAGTPDAMLDRLALNPQRIDGVAAGLRQVASLPDPVGEVLRGNTLVNGLQLRQQRVPLGVVGIVYEGRPNVTVDAFGLTLKSGNAVLLRGSSSAAHSNAALVDSLRAALVAEGLDANAVQLLPSHDRASVTHLIQARGLVDVVIPRGGAGLIDAVVRDAQVPTIETGVGNCHVYVHSAADLDMAETILLNAKTRRPSVCNAAESVLIDAAIAEEAVPRLTKALQDAGVTVHADPTEEELRAEFLSMDIALAVVDGVDAAIAHVNEYGSGHTEAIVTADLAAAQRFTERVDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIVWGDGHTRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_BLOFL
Sequence: MKLHLKGLRIAFFGTSDFAAYHLFVLIHCSIHKIVAIFTQESIKIKQKSSILSIHTISQINNILLFQSYFLSQSQINHIIKNLNIDIIIVVSYGVILSQEILHIPKLGCINIHGSLLPRWRGPAPIQRALEHGDTMTGISIIQMNSNIDTGDILHSTPCKISPKDTSYTLSKKLACIGSIALLKTIEKIILGTCKNIPQDTSNITYAYKLNKKEAHINWNKSAIEIERRIRAFNPWPVSYFKIKNQYIRVWNAEINKNSINTDQYNDFQPGTILKTHPNGIYVITGSGIIILTVLQISGKKKIHVKDLMNAYSSLFTMHSVLT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: NADE_BACC7
Sequence: MTLQEQIMKALHVQPVIDPKAEIRKRVDFLKDYVKKTGAKGFVLGISGGQDSTLAGRLAQLAVEEIRNEGGNATFIAVRLPYKVQKDEDDAQLALQFIQADQSVAFDIASTVDAFSNQYENLLGESLTDFNKGNVKARIRMVTQYAIGGQNGLLVIGTDHAAEAVTGFFTKFGDGGADLLPLTGLTKRQGRALLQELGADERLYLKMPTADLLDEKPGQADETELGITYDQLDDYLEGKAVPTDVAEKIEKRYTVSEHKRQVPASMFDDWWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: GLGC_BIFA0
Sequence: MAKKNPKILSIVLAGGEGTRLMPLTRDRAKPAVPFGGVYRLIDFPLSNLVNSGYSQVIVLTQYKSHSLDRHISQLWRFSTLLGNYVSPVPAQQRLGKHWYLGSADAVYQTINIIEDVQPDIVVIVGADHVYRMDFEQMVNQHIESGAEFTVAGIRQPIEQSSQFGVIEVDPEHPNMIKSFQEKPKETTGLPDNPNEILASMGNYVANTDALFNALSIDSKAENTKHDMGGDIAPFFAERNEAGVYDFSRNEIPGATTTDHAYWRDVGTIRQFYDAHMDLISYIPEFNLYNMEWPIYTSSGNLPPAKFVHAAGDRIGHATDSIVSPGVIVSGGEIHHSVISPNVRVHSWSQVNDSILFDNVEINRRARVNRAILDKNVVLTENSTVGLDVEHDLARGFTVTSDGITVVPKGTVVDD
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: ENDOR_ECOLX
Sequence: MSHADMSDSSGFNEAAAAFSWNGPKKAINPYLDPAEVAPFSALSNLITLYAADNEQEQLRREELSEQVWERYFFNESRDPVQREMEQDKLISRAKLAHEQQRFNPDMVILADVSAQPTHISKPLMQRIEYFSSLGRPKAYSRYLRETIKPCLERLDCVRDSQLSASFRFMASHQGLEGLLILPEMSQDQVKRLSTLVAAHMSMCLEAACGDLYATDDVKPEEIRKTWEKVAAETLRLDVIPPAFEKLRRKRNRRKPVPYELIPGSLARMLCADWWYRKLWKMRCEWREEQLRAVCLVSKKASPYVSYEAVTHKREQRRKSLEFFRSHELVNEDGDTLDMEDVVNASSSNPAHRRNEMMACVKGLELIAEMRGDCAVFYTITCPSRFHSTLNNGRPNPTWTNATVRQSSDYLVGMFAAFRKAMQPKPGCAGMACGWLSRTMTVLCTGISCVSCAKKTAAPLLHCCVSLPSVKTVRNWAITRGHALSLSGLRWYGVRVAEPHHDGTVHWHLMCFMRKKDRRAITALLRKFAIREDREELGNNTGPRFKSELINPRKGTPTSYIAKYISKNIDGRGLAGEISKETGKSLRDNAEYVNAWASLHRVQQFRFFGIPGRQAYRELRLLAGQAARQQGDKKASTPILDDPRLDAILAAADAGCFATYIMKQGVLVPRKYHLIRTAYEINEEPTAYGDHGIRIYGIWSPIVQGKICTHAMKWKMVRKAVDVQEAAADQGACAPWTRGNNCPLAENLNQQEKDKSADGDTRTDITRMDDKELHDHLHSMSKKERRELAARLRLVKPIRRKDYKQRITDHQRQQLVYELKSRGFDGSEKEVDLLLRGGSIPSGAGLRIFYRNQRLQEDDKWRNLY
What is the function of this protein?
Possible endonuclease which induces a single-strand cut and initiates DNA replication.
What are the official names of this protein?
Probable replication endonuclease from retron Ec67, Protein ORF2 in retron Ec67.
What is the protein family that this protein belongs to?
Belongs to the phage GPA family.
Protein: NCBP2_DANRE
Sequence: MSIKLNALFSDSYVDVSQYRDQHFKGNRYEQEKLLKQSATLYVGNLSFYTTEEQVHELFAKCGDVKRIIIGLDKIKKTACGFCFVEYYTRADAENAMRFVNGTRLDDRIIRTDWDAGFKEGRQYGRGKSGGQVRDEYRQDYDPARGGYGKMVQKS
What is the function of this protein?
Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export.  The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore.  The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus.  The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E.  The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs.  The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2.  The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD).  During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference.  The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation.  In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure.  The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus (By similarity).
What are the official names of this protein?
Nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, CBP20.
What is the protein family that this protein belongs to?
Belongs to the RRM NCBP2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TCP11_RAT
Sequence: MPDLKERAARKEPGAAESASRESRGGNTRESASSAQGHRSRRFNRRSSTAALTPGSAQGRGVQTAPRAPVGHGGLRTGLTSRCPQPSARAKLPSVTRGAPLPPSPGKGHFGATPISHRLGLTERVHDASKLDCHLEDRKSASSLESRGKEVMPSDFWDHLKEQLSAVPPDFSCALELLKEIKEILLSLLLPRQSRLRNEIEEALDMEFLHQQADRGDLNVSYLSKYILNMMVLLCAPVRDEAVQRLENISDPVRLLRGIFQVLGQMKMDMVNYTIQSLQPQLQEHSIQFERAQFQERLNKDPSLLNHTTKWLTQAATQLIAPSGSCYDIQDPSSSSGPSPSDIAIPEPLSPAMVLSQGFLNLLTWDPENEEFPETLLADRSRLQELESQQNQLTILASVLLVASSFSGSVLFGSPQFVDRLKRITKSLVEDFNSRPEEVMQTVSDQVTEEIHQSLKNMGLSPLSSENTDSLIGQLQNIAKKENCVRSVIDQRIHLFLKCCFVLGVQRSLLDLPGGLSLIEAELAELGQKFVSLTHHNQQVFAPYYTEILKTLINPVQTLTTKVGSL
What is the function of this protein?
Plays a role in the process of sperm capacitation and acrosome reactions.  Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway.
What are the official names of this protein?
T-complex protein 11 homolog.
What is the protein family that this protein belongs to?
Belongs to the TCP11 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Localizes on the acrosomal cap region of acrosome-intact, but not acrosome-reacted sperm. Colocalizes with MROH2B and PRKACA on the acrosome and tail regions in round spermatids and spermatozoa regardless of the capacitation status of the sperm.