PharMolix/UniProtQA huggingface dataset:
Protein: ILVD_CELJU
Sequence: MPVYRSKTTTSGRNMAGARALWRATGMKDEDFQKPIIAVANSFTQFVPGHVHLKDLGQLVAREIEKAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHCADALVCISNCDKITPGMLMAAMRLNIPVIFVSGGPMEAGKTRLAEHKLDLVDAIVIGTDKNASDEQVEAYERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSLLATHADREQLFLEAGRRIVEITKRYYEQDDASVLPRAIATFEAFENAMALDIAMGGSTNTILHLLAAAQEGGVPFTMTDIDRLSRKVPQLCKVAPNTQKYHMEDVHRAGGVVGILAELNRGGLLHNQVPTVHSKTLQEGLDQWDIISTGSDAVATFYRAGPAGIPTQVAFSQATRWPTLDADRVEGCIRSVEHAYSKEGGLAVLRGNIALDGCVVKTSGVDESIWVFEGPAYVVESQDQAVKDILDGKVKAGDVVVIRYEGPRGGPGMQEMLYPTSYLKSQGLGKACALLTDGRFSGGTSGLSIGHVSPEAAAGGAIGLVETGDIIHIDIPNRSINVKLSNQELAERRDAMAAKGNKAWKPIEARPRKVSASLKAYAMLATSADKGAVRDLSKLD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PETD_NOSS1
Sequence: MATHKKPDLSDPTLRAKLAKGMGHNYYGEPAWPNDLLYVFPIVIMGSFACIVALAVLDPAMTGEPANPFATPLEILPEWYLYPVFQILRSLPNKLLGVLAMASVPLGLILVPFIENVNKFQNPFRRPVATTVFLFGTLVTLWLGIGAALPLDKSLTLGLF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: RPA2_DANRE
Sequence: MDLSKWCNLKTEPSLKHLTEAGFGVPKEKQSVPVQELVKAHIESFDQAVTDGLCRVVEAIPPMEFLYKGDRISLSFVEAIIHTPSVSKGGISRDLRVFPAECRGRRCTYRAKLVADVSWSVNGVPKGIIKQSLGQMPIMVKSKLCNLHGLSPKELLEHHEEAEEMGGYFIVNGIEKVIRLLIMPRRNYPIAVSRPKFKSRGQGYTQYAISMRCVKEEHTAINMNLHYLDNGTVMVNFIYRKELFFLPLGFALKALVDYSDYQIYQELIKGREDNSFYKSCVSEMLRIVMDQGCTTKIKVLNYLGERFRVKLNLPEWFTHEQCAHFLLDECLCIHLKTDVEKFYMLCLMTRKLFSFAKQECMEENPDSPMFHEVLTPGQLYLMFLKEKMEGWLVSVKLALEKKPQRVGGLTPDSMTKLFNMGTDLTKAFEYLLATGNLMSKTGLGMLQNSGLCVVADKLNFIRYLSHFRCVHRGAAFAKMRTTTVRKLLPESWGFLCPVHTPDGEPCGLMNHMTAHCEIVAPVYPTSTLPGLLCSLGVNAADGNPGQAYSDCYPVILDGAMIGWVEKEVAPSVIESLRRFKVLGEKKVPPWTEIVLVPQTGKASLYPGLYLFTTPCRMVRTVRNLSLGKQELIGIFEQVYLNVGIFEKEIEDGVTTHQELFPHSMLSVVAEFIPFSDHNQSPRNMYQCQMSKQTMGFPLHSYQYRSDNKLYRLQTPQSPLVRPAMYDHYDVDNYPIGTNAIVAVISYTGYDMEDAMIVNKSSWERGFAHGSVYKTEIIDLSEKVKGDDSIVFGVKPGDPKVMGKLDADGLPFIGSVLKYGDPFYGYISLNTGQSHVYFYKYQESCVVDNIKVCSNETGTGRFKRICVTSRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMSPDILFNPHGFPSRMTIGMLIESMAGKSASLHGLCHDATPFTFSEENSALEHFGELLKAAGYNYYGTERLYSGLSGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDKVTNQPMGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAQVCMDCGSLLSPLLEKPPPNWSATRHRKTICLLCNKSDSIETVSVPYVFKYFVAELAAMNIKIKLDVK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA2, RNA polymerase I subunit 2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome.
Protein: BAMA_YERPB
Sequence: MAMKKLLIASLLFGSATVYGADGFVVNDIHFEGLQRVAVGAALLNMPVRVGDTVSDDDIGKTIRALFATGNFEDVRVLRDGNTLIVQVKERPTIASITFSGNKAVKEDMLKQNLEASGVRVGEALDRTTISNIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFTEGVSAKIQQINIVGNHSFTTDELISRFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSFYLDRGYARFNIDSTQVSLTPDKKGIYVTINITEGPQFKLNSVIVSGNLAGHQSEAEKLTKIEPGELFNGSKVTRMEDDIKKMLGRYGYAYPRVVTQPEINDDDKTVKLHINVDAGNRFYVRHIRFEGNDTSKDSVLRREMRQMEGAWLGNDQVEAGKERLNRLGYFETVDVETQRVPGAADLVDVTYKVKERNTGSLNFGIGYGTESGVSFQVGVQQDNWLGTGNTVGINGTKNDYQTYAEFTLMDPYFTVDGVSLGGRIFYNDFKADNADLSGYTNSSYGADGTLGFPINENNSLRVGVGYVHNDLSDMLPQVAMWRYLESVGERPGYDGREGFTTDDFTLNLGWTYNNLDRGFFPTSGVKSSVNTKITVPGSDNEFYKVTFDTSAYQPLNEDRSWVLLGRGRLGYGDGIGSKEMPFYENFYAGGSSTVRGFRSNNIGPKAAYYANGGATVTNSTDAVGGNAMAVASIELITPTPFISEKYSNSVRTSIFIDSGTVWDTNWENTAKTRAAGIPDYGKASNIRVSAGVALQWMSPLGPLVFSYAKPVKDYEGDKSEQFQFNIGKTW
What is the function of this protein?
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.  Constitutes, with BamD, the core component of the assembly machinery.
What are the official names of this protein?
Outer membrane protein assembly factor BamA.
What is the protein family that this protein belongs to?
Belongs to the BamA family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GILT_CARAU
Sequence: MFGFRLSVLLFAVCSLSACSCMFVNSCKYPPSQWCDSRDIAAQCGVLEQCMKFNASPVTVSLYYESLCPGCREFLVSQLVPTFIMLSDIMNIELVPYGNAQEKDDQGNYTFICQHGEDECRGNMIETCLLKALGPKAIPVIFCMESGADVLKAAQPCLGVYFPDTTWDSVMKCVTGDEGNKLMHQNALKTNALKPPHEYVPWITINGEHTDDLQDKATNSLFNLVCSLYKGEKPAACGQGLKKRTNSYCMN
What is the function of this protein?
Lysosomal thiol reductase that can reduce protein disulfide bonds.  May facilitate the complete unfolding of proteins destined for lysosomal degradation.  Plays an important role in antigen processing.
What are the official names of this protein?
Gamma-interferon-inducible lysosomal thiol reductase.
What is the protein family that this protein belongs to?
Belongs to the GILT family.
What are the subcellular locations of this protein?
Secreted. Lysosome.
Protein: Y4E9_ENCCU
Sequence: MGDHTYKKKDSGIYDALNMLVYDYLLKMKYEGSAKIFFNEAGLENFKPGEGMPILAQWYAAFHDISAVRSGLSSNLQDLNRIEGIMMKLENEKRRYQHIGRIDPGAMGYGGTVDPYKQYPMYYQQFDQRKMYEMYGQMSPTADATPRFYDPRKGSMPGPGYRAAQGYPRYHPRFEEQGVPPAKMAPKQFRDEGRSGNVESPSIATNQEGSSPLFESVLGGGDRQFGLKEVMLFVPSEHTAVCSAVAGEHKILLVASSNKTITAVNLLSGKNESTVETDEKQVVEMKIREYEDEIIVVCGIADNELLLVRCTMKGSANLEIAGILRGHTASIVSFEVLDSIHSLDSGGIMRKWTLNGVFEREEVLSGEILHICCISEDNFMFADRQRVYVYDFELNIEMMEILKGQALGIKRIKDGFIVVFRNQAIWLDKRIQKVKVLNVNESIRTATLIDGDLVAASSQNVWFDNGKSLAKIKLHETGIVALDGVNVFRKPSVISCSASGECKIWIKYVGD
What are the official names of this protein?
Uncharacterized LisH domain-containing protein ECU04_1490.
Protein: QUEC_XANOP
Sequence: MKKAVVLLSGGMDSAAVIALAQEQGFAVYALSVRYGQRHTSELDAAARVAAAQGVVAHKVVDVDLRSIGGSALTDDIDVPDAGGDGIPVTYVPARNTIMLSLALGWAEVVGANDLFCGVNAVDYSGYPDCRPEFVRAFEVLANLATKAGVEGAGLRVHAPLQFLSKADIVREGVRLGVDFGLTVSCYRADADGRACGHCDACRLRAAGFADAGVPDPTHYAILS
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: YIDC_PEDPA
Sequence: MKHLKRNMALLSVAALSFILTACSTAPITSHSTGIWDGVIVYNFSRFIIYLSKLFGGNYGWGIIVFTIIIRIIILPLMIYQTRTTMKTAELQPKLKQLQQKYSSRDAESQQKLREEQQKLYAEAGVNPMAGCLPLIIQLPVMYALYAAVSRTQVLKEGTFLWLQLSDKDPYFILPILAALFTFMSTWLSMKSQPAGSQNGMTSAMTFGMPLVILITALNFPAAITLYWVVTNLFQVGQTLIIQNPFKIQKEREEKIQTEKAKRKAIEKAKRRAMKSKRK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CMOA_VIBCH
Sequence: MRSAMNPKDTLFSAPIDKIGDFTFDERVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKPHSKIYDLGCSLGAATLSMRRHIKQEGCQIIAVDNSAAMVERCKLHLNAYRSDTPVQVIEADIRDIAIENASVVVLNFTLQFLAPDDRYALLEKIYAGLRPGGILILSEKFVFSDQEAHELLIDLHHDFKRANGYSELEISQKRSAIENVMRPDSIQTHKQRFATLGFSSFEVWFQCFNFGSMFAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: TORA_VIBVU
Sequence: MAITRRSFLKGVATTSAASVIGPSLLASASANAVETTGTWKVSGSHWGAFRAHIYAGKVQEIKPIELDQNPTEMLNGIKGIIYSPSRVRYPMVRLDWLKKHKYSADTRGNNRFVRVTWDEALDLFYRELERVQKEYGPWALHAGQTGWNQTGSFNNCTAHMQRAVGMHGNYITKVGDYSTGAGQTILPYVLGSTEVYAQGTSWSEILENADNIILWANDPVKNLQVGWNCETHESYAYLAQLKEKVAKGEINVISVDPVKNKTQRYLENDHLYVNPMTDVPFMLAIAHVLYTENLYDKKFIETYCLGFEEFINYVQGKTKDKVEKTPEWAAPICGVKADKIREFARMLVKGRTQILMGWCIQRQEHGEQPYWAAAVVAAMIGQIGLPGGGISYGHHYSSIGVPSTGFAGPGGFPRNLDAGMKPKWDNNDFNGYSRTIPVARWIDCLLEPGKEINYNGGKVKLPDFKMMVISGCNPWHHHQDRNRMKQAFQKLQTVVTIDFAWTATCRFSDIVLPACTQWERNDIDVYGSYSSRGLIAMHRLVDPLFQSKPDFQIMKELTERFGRSEEYSRGMSEMDWIRSLYNDCKKSNEGKFEMPEFDEFWEKSVLDFGQGQPWVRHADFRQDPEINPLGTPSGFIEITSRKIGRYGYEHCQEHPMWFEKSERSHGGPGSDKHPFWLQSCHPDKRLHSQMCESEEFRATYAVKGREPVYINPLDAKAKGIKEGDLVRVFNDRGQLLAGAVLTDSYPRGVIRIEEGAWYGPLNEKVGAIDTYGDPNTLTQDIGSSELAQATSANTCIVDFEKFTGKVPPVTSFGGPIEVA
What is the function of this protein?
Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.
What are the official names of this protein?
Trimethylamine-N-oxide reductase, TMAO reductase, Trimethylamine oxidase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LEU3_SYNS9
Sequence: MAQYRVVLLPGDGIGPEITAVARQLLDVVAQRHGFQLMFEEQPIGGSAIDATGEPLPASTLTACRSADAVLLAAIGSPRFDSLPREKRPETGLLGLRSGLELFANLRPVKIVPALIGASSLKQEVIEGVDLMVVRELTGGIYFGQPKGRIEADGDERGFNTMTYSASEVDRIAKVAFEIAGERNNRLCSVDKANVLDVSQLWRDRVDAMAPRYGEVDVSHMYVDNAAMQLVRDPRQFDVLLTGNLFGDILSDEAAMLTGSIGMLPSASLGSDGPGLFEPVHGSAPDIAGQDKANPMAMVLSAAMMLRIGLKQSSAADDLERAVDAVLASGFRTGDLMSEGCTPLGCQAMGEQLLKAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_STRCO
Sequence: MARVKRAVNAHKKRRAILEQASGYRGQRSRLYRKAKEQVTHSLVYNYNDRKKRKGDFRQLWIQRINAAARANGITYNRFIQGLKAANVEVDRKILAELAVNDPNAFAALVEVAQKALPSDVNAPKAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: ATPG_CAMJ8
Sequence: MSNLKEIKRKIKSVHNTQKTTNAMKLVSTAKLKKAEEAAKRSKIYAQKIDEILSEISFQINKIVHNEDDVRLSLFHKKEQIKTVDLIFITADKGLCGGFNIKTLKAVSEMLKEYEAKNINIRLRAIGKTGIEYFNFQKIELLEKYFHLSSSPDYEKACEVIHAAVDDFLNGNTDEVILVHNGYKNMITQELKINHLIPVEPKSIEQTHNSLLELEPEGTELLEDLMKTYFEYNMYYALIDSLAAEHSARMQAMDNATNNAKARVKQLNLAYNKARQESITTELIEIISGVESMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PN3B_PAMNI
Sequence: GCRYMFGDCEKDEDCCKHLGCKRKMKYCAWDFTFT
What is the function of this protein?
Gating-modifier toxin that targets voltage-gated sodium channels with a preferential activity on Nav1. 7/SCN9A.  On Nav1. 7/SCN9A, the toxin acts by shifting the voltage-dependence of activation to more depolarized potentials, whereas it does not cause significant effect on the voltage-dependence of activation on other sodium channels.  Minor effects are observed on the voltage-dependence of steady-state fast inactivation for all sodium channels tested (Nav1. 1/SCN1A-Nav1. 8/SCN10A).  By testing the toxin on channel chimera, it has been shown to interact with the S3-S4 linkers in DII and DIV domains of Nav1. 7/SCN9A.  In vivo, the toxin dose-dependently reduces OD1-induced spontaneous pain behaviors.
What are the official names of this protein?
Mu-theraphotoxin-Pn3b, Mu-TRTX-Pn3b.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 28 (Jztx-11) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GBLP_LEIIN
Sequence: MNYEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPDRHSVDSDYGLPSHRLEGHTGFVSCVSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGECMHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCASGGKDGAALLWDLSTGEQLFKINVESPINQIAFSPNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPSECISIAWSADGNTLYSGHKDNLIRVWSISDAE
What are the official names of this protein?
Guanine nucleotide-binding protein subunit beta-like protein, Antigen LACK, LiP36, p36Li.
What is the protein family that this protein belongs to?
Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
Protein: RL11_PYRAB
Sequence: MKKQVVEVLVEGGKATPGPPLGPAIGPLGLNVKQVVDKINEATKEFAGMQVPVKIIVDPVTKQFEIEVGVPPTSQLIKKELGLEKGSGEPKHNIVGNLTMEQVIKIAKMKRNQMLALTLKAAAKEVIGTALSMGVTVEGKDPREVQREIDEGVYDELFEKAEKE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: LOLD_MANSM
Sequence: MNNGILLNCQNLTKDYIEGSVTTRVLKDVTFSMNDKELVAIVGSSGSGKSTLLHTLGGLDQPTSGEVFIKGKSLQKASQDELAKLRNTYLGFVYQFHHLMADFTALENVLMPMLIGNQNKTEAKDRAEKMLNAVGLSHRITHKPSALSGGERQRVAIARALVNNPALVLADEPTGNLDHKTTESIFELIQQLNEDQGIAFLLVTHDLNLAEKLNRRLIMQDGVLRPEM
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: OBL_OBEGE
Sequence: MASKYAVKLQTDFDNPKWIKRHKFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAFFRGCGLEYGKETKFPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTRQHLGFWYTLDPEADGLYGNGVP
What is the function of this protein?
Ca(2+)-dependent bioluminescence photoprotein.  Displays an emission peak at 495 nm (blue light).  Trace amounts of calcium ion trigger the intramolecular oxidation of the chromophore, coelenterazine into coelenteramide and CO(2) with the concomitant emission of light.
What are the official names of this protein?
Obelin, OBL.
What is the protein family that this protein belongs to?
Belongs to the aequorin family.
Protein: PARP1_ARATH
Sequence: MASPHKPWRAEYAKSSRSSCKTCKSVINKENFRLGKLVQSTHFDGIMPMWNHASCILKKTKQIKSVDDVEGIESLRWEDQQKIRKYVESGAGSNTSTSTGTSTSSTANNAKLEYGIEVSQTSRAGCRKCSEKILKGEVRIFSKPEGPGNKGLMWHHAKCFLEMSSSTELESLSGWRSIPDSDQEALLPLVKKALPAAKTETAEARQTNSRAGTKRKNDSVDNEKSKLAKSSFDMSTSGALQPCSKEKEMEAQTKELWDLKDDLKKYVTSAELREMLEVNEQSTRGSELDLRDKCADGMMFGPLALCPMCSGHLSFSGGLYRCHGYISEWSKCSHSTLDPDRIKGKWKIPDETENQFLLKWNKSQKSVKPKRILRPVLSGETSQGQGSKDATDSSRSERLADLKVSIAGNTKERQPWKKRIEEAGAEFHANVKKGTSCLVVCGLTDIRDAEMRKARRMKVAIVREDYLVDCFKKQRKLPFDKYKIEDTSESLVTVKVKGRSAVHEASGLQEHCHILEDGNSIYNTTLSMSDLSTGINSYYILQIIQEDKGSDCYVFRKWGRVGNEKIGGNKVEEMSKSDAVHEFKRLFLEKTGNTWESWEQKTNFQKQPGKFLPLDIDYGVNKQVAKKEPFQTSSNLAPSLIELMKMLFDVETYRSAMMEFEINMSEMPLGKLSKHNIQKGFEALTEIQRLLTESDPQPTMKESLLVDASNRFFTMIPSIHPHIIRDEDDFKSKVKMLEALQDIEIASRIVGFDVDSTESLDDKYKKLHCDISPLPHDSEDYRLIEKYLNTTHAPTHTEWSLELEEVFALEREGEFDKYAPHREKLGNKMLLWHGSRLTNFVGILNQGLRIAPPEAPATGYMFGKGIYFADLVSKSAQYCYTCKKNPVGLMLLSEVALGEIHELTKAKYMDKPPRGKHSTKGLGKKVPQDSEFAKWRGDVTVPCGKPVSSKVKASELMYNEYIVYDTAQVKLQFLLKVRFKHKR
What is the function of this protein?
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism.  This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity).
What are the official names of this protein?
Poly [ADP-ribose] polymerase 1, PARP-1, NAD(+) ADP-ribosyltransferase 1, ADPRT-1, Poly[ADP-ribose] synthase 1, Protein ADP-ribosyltransferase PARP1.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYY_LACDB
Sequence: MANFDILEDLKWRGAINQETDEEGLRDYLAKHDDLALYCGTDPTGDSLHIGHLIPFMILKRFQLAGYKPVIVIGGGTGSIGDPSGRSTERVLQSEETIKHNEEALTAQMVKLFGTENFRIVNNRDWLGKMNLLEFLRDYGKLFQVNNMLNKEVVASRLKNGISFTEFSYQILQAIDFYILNRDHGVQMQIGGADQWGNITAGIDLIHRLEGADRPAFGLTIPLMLKADGTKFGKSAGGAVWLDPEKTSPYEFYQFWINQDDRDVIKYLKYFTFLKHEEIDALEEKVKTEPWKREAQKRLAEEVTKFVHGEEGLKEAQTVTEALFSGNVKDLTTKQVEIALAKAPSAESGEEKKNLVDFLVDTKIESSKRQAREDVNNGAIYVNGDRIQDTDFEVDPAAAFDGKFVIIRKGKKKYTLVHIKG
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_METFK
Sequence: MAKRDYYEVLGVNRDATDEEIKKAYRKLAMKYHPDRNPDNPKAEEHFKEAKEAYEVLSDDQKRAAYDQYGHAGVDPSAAAGAGAGGFGNFADAFGDIFGDIFGGGGGGRRSNVYRGADLRYNMEISLEEAARGTETKIRIPVMAECETCHGSGARPGTQPVTCSTCGGHGQVRMQQGFFSVQQTCPKCHGSGKMVKDPCPTCHGGGRVKQHKTLSVKIPAGVDEGDRIRLSGEGEAGVNGGPPGDLYVVVHLKKHPIFERDGANLHCEMPISFTTAALGGEIEIPTLDGHAKMKVPPETQTGAVFRLRGKGIKPLRSNEHGDLFCHVIVETPVKLTERQKELLRELEDINQQDSGKHSPREKSWMTKVKDFFQ
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_SOLUE
Sequence: MIQPDSYVRSLLKRSPGESVTARGWVKTRRDSKNVHFIQLNDGSSPVDLQVVLDAGVVPEDVVAKITTGACISVEGDLVASMGKGQAVEIKARALTVHGTADPEHYPLQKKKHTLETLRELGHLRTRSNTFGAVFRVRNALACAIHKFFQDRGFMYVHTPVISASDAEGAGSMFQVTTLDLQSPKPADFTGDFFGKHTYLTVSGQLEAEIFAHAFANVYTFGPTFRAENSNTPRHLAEFYMIEPEMAFCDLKDNQDLAEAFLKSQVEYVVNACGPDLDFLAKWYDPELRKTLDGLMNASFERITYTEAIDLLQRSGRSFEFPTQWGSDMQSEHERYLTEEVFNKPVIVTDYPKDIKAFYMRGNDDGKTVAAMDVLAPRIGEIIGGSQREERHDVLLQRIREMAAHGLREEAYWWYLDLRRFGGVEHAGFGMGFERMLMYLTGMKNIRDVIPFPRTPGNAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_LACLS
Sequence: MVKNTEDKPLAQNKKARHDYEIYETFEAGIVLTGTEIKSVRQAKIQLKDGFARVRNGEVWLSNVHIAPFEQGNIFNVEELRTRKLLLNKKEIAKIDKELSGTGITFIPLKVYLKNGFAKVLMGLARGKKDYDKRESLKRKEQNRDIARQLKAYNR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: PYRH_GRAFK
Sequence: MHYERILLKLSGEALMGNRQYGIDPERLAEYAAEIKSVVDKGVEVAIVIGGGNIFRGVAGASRGMDRVQGDHMGMLATVINGLALQSALEDANIQTRLQSAIKINEVAEPFIRRKAIRHLEKGRVVIFGGGTGNPYFTTDSAAVLRAIEIKADVILKGTRVDGIYTSDPEKNKEATKFDFITFEDVIKKGLKVMDTTAFTLSQENELPIIVFDMNKPGNLLKVATGERVGTKVNL
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCRO_BPD3
Sequence: MTTIYKELVAHFGTQDETAAKLGVDQSTVSGWVRGKHGMSPVVAKRAQVLTDGKFKKEDLCPAFPWEVLSAVA
What is the function of this protein?
Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth.  It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance (By similarity).
What are the official names of this protein?
Regulatory protein cro, Antirepressor.