PharMolix/UniProtQA huggingface dataset:
Protein: GET2_LODEL
Sequence: MSETTDKQLTEAEKRKLLRERRLAKMAQGKASDRLNTILSQGSSVKSVSPPAVTSVLENKATKSTDTATVTDSSTNATSVSPSAAKATPTSTGVSSAISDFDDPEIQDISDVAVNNSGVLALGNLSGLDSNNPSQPNLDEMFQKIMQQQSQHNCDNDNNGENNPMAEMLKMFNSMGGGDNNGGLGGFDSMFSGSPNSPPPESISPEMMKYQADLAKYHTYQEQLWQFRFLVVRILATIFNFAYHFITIPSFTASNHAYVRDLSEVYPLLGFMTIFTSIEVVIIATYYLLFTKLGLFHASNQKSFILKGISTLSMFVPQLLRYEPLVATFLGYKELLGIFVGDLSLVVVMFGLLSFSN
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RS13_CAMHC
Sequence: MARISGVDLPKKKRIEYGLTYIYGIGLFTSRKILDATGISYDKRVADLSEDEVAAIRKEIQEHYMVEGDLRKEVSMNIKSLMDLGCYRGLRHIKGLPVRGQKTKTNARTRKGKRKTVGAVSAAANKE
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GLMU_ALKMQ
Sequence: MKLKAIILAAGTGTRMKSKMPKVLHKVCGQTMLGHVIDVSKDSKAEECIVVVGHGAEEVQKTLPEGVKTVLQAEQLGTGHAVMVAEEHIETQGTVLVLYGDGPLITEETLNALMTYHQEGKYSATVLTAELENPTGYGRIIRDDDDRLKTIVEEKDTTVGEKEVREINSGIYCFDSKVLKETLPKIQNNNSQKEYYLTDALTIIKQEGLKVGVYQIENYEDIMAVNSREQLAEVEEVMQRRIVKKHMEAGVTFIDPQSTYIEKTVKVGMDTILHPGVILKGATEIGEDCIIGHNSRIENSILKNGIEVQSSTIIESTIDDHATIGPYAYLRPQSHIGKHVKVGDFVEVKNATIDDHSKAAHLAYIGDAEIGKHVNIGCGVIFVNYDGIKKHKTIIKDHAFVGSNSNLVAPITIQESAFVASGSTITREVPAGALAVGRSRQENKEGWVARKGVGKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C6A20_DROME
Sequence: MAVMIVLLIGVITFVAWYVHQHFNYWKRRGIPHDEPKIPYGNTSELMKTVHFADIFKRTYNKLRNKTDGPFVGFYMYFKRMVVVTDIDFAKTVLIREFDKFHDRGVFHNERDDPLSANLVNIDGQKWKTLRQKLTPTFTSGKMKTMFPTILTVGDELIRVFGETASADSDSMEITNVVARFTADVIGSCAFGLDCHSLSDPKAKFVQMGTTAITERRHGKSMDLLLFGAPELAAKLRMKATVQEVEDFYMNIIRDTVDYRVKNNVKRHDFVDMLIEMKLKFDNGDKENGLTFNEIAAQAFIFFLAGFETSSTTMGFALYELACHQDIQDKLRTEINTVLKQHNGKLDYDSMREMTYLEKVIDETMRKRPVVGHLIRVATQHYQHTNPKYNIEKGTGVIVPTLAIHHDPEFYPEPEKFIPERFDEDQVQQRPACTFLPFGDGPRNCIGLRFGRMQVIVGMALLIHNFKFEFHPTKTVVPLEYRTDDFLLSSKGGIHLKVTRV
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 6a20, CYPVIA20.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RNJ_PYRAB
Sequence: MWEEINMIKIYTLGGYEEVGKNMTAVEYNGEVVIVDMGIRLDRVLIHEDVEFQKMSSKDLRKLGAIPDDRPIRNKKVVAIALSHGHLDHIGAVGKLAPHYPDVPIYGTPYTIRLAKSEIKGEEYFEVTNPLYETNYGEIVQVSENLAIEFVQITHSIPQSSIVVIHTPEGAVVYACDYKFDNNHPYGERPDYKRLKELGKEGVKVLIAESTRVAEETKTPSEAVAKMLLEDFFLYEGMEADGLIATTFASHIARLQELIEIANKMGRQAIFIGRSLAKYTGIAKQLGLIKMKGSRVLRSPNAVSKVLKEVSQARENYLLIVTGHQGEPGAILTRMANGELYDIGPRDTVVFSAGVIPNPLNVAQRYALETKLRMKGVRMIKNLHVSGHASKEDHRYLIRMLNPEYIVPAHGEFRMLTHYAELAEEEGYMIGKEVFISRNGHVVEIPGSLEG
What is the function of this protein?
A highly processive 5'-3' exoribonuclease; no evidence has been seen for endonuclease activity.  Prefers 5'-phosphate or 5'-hydroxyl ends; 5'-triphosphate substrates are very poorly degraded, does not degrade circular RNA.  Does not degrade pre-tRNA(Trp) suggesting it is inhibited by strong secondary structures.  Also degrades ssNDA but not dsDNA.
What are the official names of this protein?
Ribonuclease J, RNase J, Pab-RNase J.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_BURM1
Sequence: MNVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKDSGVNVTVGLRKGGASWSKAENAGLAVKEVAEAVKGADVVMMLLPDEQIADVYAKEVHANIKQGAALAFAHGFNVHYGQVIPRADLDVIMIAPKAPGHTVRGTYSQGGGVPHLIAVAQNKSGAARDIALSYAAANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEETKKAMKQCLTDIQTGEYAKSFILENKAAAPTLQSRRRLTAEHQIEQVGAKLRAMMPWIAKNKLVDQTKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: SLX1_CANDC
Sequence: MSQTNDKPALHLVPSFYGVYILKSIPKPRRTYIGSTPDPKRRLRQHNGDLKVGGAYRTKKDGSRPWTMVVLVHGFPSRIAALQFEHSLQHAYQTRHINNDARITSSSRQSSMHSKLANIRLLTTSFDKMSLKIAIFDEEVYRMWVENKHKIECNVPCTLFKFDEFCNSIQEIDIEDAKNILLGKQLDCMVCKASIDYFKDSTPNISSREELSNYLAKGNYPLIGICGDHAFHLSCIARQRGPAMVPKSVTCTTCGQKLDWSDIIKVSTRLRHYVVQDSLHLAITQL
What is the function of this protein?
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX1.
What is the protein family that this protein belongs to?
Belongs to the SLX1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YIDD_STRMU
Sequence: MKKVLIAPIKFYQKFISPIFPASCRYRPTCSAYMIEAIEKHGLKGFLMGIARILRCHPFVEGGEDPVPNHFTLRRNKKEKPSKS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDVA_BRUSU
Sequence: MSLLKIYWRAMQYLAVERTATITMCVASVLVALVTLAEPVLFGRVIQSISDKGDIFSPLLMWAALGGFNIMAAVFVARGADRLAHRRRLGVMIDSYERLITMPLAWHQKRGTSNALHTLIRATDSLFTLWLEFMRQHLTTVVALATLIPVAMTMDMRMSLVLIVLGVIYVMIGQLVMRKTKDGQAAVEKHHHKLFEHVSDTISNVSVVQSYNRIASETQALRDYAKNLENAQFPVLNWWALASGLNRMASTFSMVVVLVLGAYFVTKGQMRVGDVIAFIGFAQLMIGRLDQISAFINQTVTARAKLEEFFQMEDATADRQEPENVADLNDVKGDIVFDNVTFEFPNSGQGIYDVSFEVKPGQTVAIVGPTGAGKTTLINLLQRVFDPAAGRIMIDGTDTRTVSRRSLRHAIATVFQDAGLFNRSVEDNIRVGRANATHEEVHAAAKAAAAHDFILAKSEGYDTFVGERGSQLSGGERQRLAIARAILKDSPILVLDEATSALDVETEEKVKQAVDELSHNRTTFIIAHRLSTVRSADLVLFMDKGHLVESGSFNELAERGGRFSDLLRAGGLKLEDKQPKQPVVEGSNVMPFPVKGAVA
What is the function of this protein?
Involved in beta-(1-->2)glucan export.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity).
What are the official names of this protein?
Beta-(1-->2)glucan export ATP-binding/permease protein NdvA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Beta-(1-->2)glucan exporter (TC 3.A.1.108.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MYH8_CANLF
Sequence: MSASSDAEMAVFGEAAPFLRKSEKERIEAQNKPFDAKTSVFVAEPKASYVKSTIQSKEGGKVTVKTEGGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQNLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIEKPLGIFSILEEECMFPKATDTSFKNKLYDQHLGKSANFQKPKVVKGKAEAHFSLIHYAGTVDYNIGGWLDKNKDPLNDTVVGLYQKSAMKTLASLFSTYASAEADSGAKKGAKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQFIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLSQIITRTQAVCRGFLMRVEYQKMLQRREALFCIQYNIRAFMNVKHWPWMRLFFKIKPLLKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADALADAEERCEQLIKNKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQERKLRMDLERAKRKLEGDLKLAQESTMDAENDKQQLDEKLKKKEFEISNLLSKIEDEQAIEIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNAETISKAKGNLEKMCRTLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKRQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLAEWKQKYEETQAELEASQKEARTLSTELFKVKNAYEESLDQVETLKRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCDIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRVMESMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKTAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVHELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-8, Developmental myosin heavy chain neonatal, Myosin heavy chain 8, Myosin heavy chain, skeletal muscle, perinatal, MyHC-perinatal.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: PTC1_AGACL
Sequence: MAFLKKSLLLVLFLGLVSLSICEEEKRENEDEEKQEDDDQSENKRGLLSGILNTAGGLLGNLIGSLSNGES
What is the function of this protein?
Neutral peptide with no antimicrobial activity.  May act in synergy with cationic peptides by enhancing their activity.  Has a moderate hemolytic activity.
What are the official names of this protein?
Plasticin-C1, DRP-AC1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Plasticin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: AP3M2_MOUSE
Sequence: MIHSLFLINSSGDIFLEKHWKSVVSRSVCDYFFEAQERATEAENVPPVIPTPHHYLLSVYRHKIFFVAVIQTEVPPLFVIEFLHRVVDTFQDYFGVCSEPVIKDNVVVVYEVLEEMLDNGFPLATESNILKELIKPPTILRTVVNTITGSTNVGDQLPTGQLSVVPWRRTGVKYTNNEAYFDVVEEIDAIIDKSGSTVTAEIQGVIDACVKLTGMPDLTLSFMNPRLLDDVSFHPCVRFKRWESERILSFIPPDGNFRLLAYHVSAQNLVAIPVYVKHSISFRDSSSLGRFEITVGPKQTMGKTIEGVIVTSQMPKGVLNMSLTPSQGTHTFDPVTKMLSWDVGKINPQKLPSLKGTMGLQVGASKPDENPTINLQFKIQQLAISGLKVNRLDMYGEKYKPFKGIKYMTKAGKFQVRT
What is the function of this protein?
Component of the adaptor complexes which link clathrin to receptors in coated vesicles.  Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.  Ap47 is a subunit of the plasma membrane adaptor (By similarity).  In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
What are the official names of this protein?
AP-3 complex subunit mu-2, Adaptor-related protein complex 3 subunit mu-2, Clathrin assembly protein assembly protein complex 3 mu-2 medium chain, Clathrin coat assembly protein AP47 homolog 2, Clathrin coat-associated protein AP47 homolog 2, Golgi adaptor AP-1 47 kDa protein homolog 2, HA1 47 kDa subunit homolog 2, Mu3B-adaptin, m3B, P47B.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: MTAP_SACS2
Sequence: MIEQNEKASIGIIGGSGLYDPGIFSESKEIKVYTPYGQPSDFITIGKIGNKSVAFLPRHGRGHRIPPHKINYRANIWALKELGVRWVISVSAVGSLRMDYKLGDFVIPDQFIDMTKNREYSFFDGPVVAHVSMADPFCNSLRKLAIETAKELNIKTHESGTYICIEGPRFSTRAESRTWREVYKADIIGMTLVPEVNLACEAQMCYATIAMVTDYDVFAEIPVTAEEVTRVMAENTEKAKKLLYALIQKLPEKPEEGSCSCCNSLKTALV
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP, MTAPII.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: NTPPA_LAWIP
Sequence: MTQQRVSSVFIETVPIVLASASPRRRSLLEQLGLLFKIVSVDSEPLPLSSEHPLEYVIRAAKVKAFAAAALEPRSVIIAADTVVIYTKDDVFEIIGKPQSGNDSFSMLSRFQGGKHQVITGCCIVWPLEENITSVQYEIFYDTASIQFGQWDKDILSSYVSTGESNDKAGAFSIQGIGAFLIDIIEGNYTTILGLPLPQLVKRLLKRKAIKVVLNKNSEETISSDFLTYSR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLPD_SALDU
Sequence: MSAGSPKFTVSRIAALSLVSLWLAGCTSSSNPPAPVTSVDSGSSSNTNSGMLITPPPKMGATTQQTPQQAPQIQPVQRPVTQPMQTQPVTEQPVQMENGRIVYNRQYGNIPKGSYTGGSTYTVKKGDTLFYIAWITGNDFRDLAQRNSISAPYSLNVGQTLQVGNASGMPITGGNAITQADAAQQGVVTRSAQNSTVAVASQPTITYSEGSGEQSANKMLPNNKPAGTVVTAPVTAPTVSTTEPNASSTSTSAPISAWRWPTDGKVIENFGASEGGNKGIDIAGSKGQAIVATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR
What is the function of this protein?
Activator of the cell wall hydrolase AmiC.  Required for septal murein cleavage and daughter cell separation during cell division (By similarity).
What are the official names of this protein?
Murein hydrolase activator NlpD.
What is the protein family that this protein belongs to?
Belongs to the E.coli NlpD/Haemophilus LppB family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor. Note=Localizes at the septal ring.
Protein: MUTS_BURCJ
Sequence: MTTLSPEAFAGHTPMMQQYLRIKADHPDTLVFYRMGDFYELFFEDAEKAARLLDLTLTQRGASAGTPIKMAGVPHHAVEQYLAKLVKMGESVAICEQIGDPATSKGPVERKVVRVVTPGTLTDAALLSDKNDVYLLAMCTGHNKRGVAVNIGLAWLNLASGALRLAEIESEQLAAALERIRPAEILTPDGATDAIPAGAGASKRVPAWHFDIASGTQRLCDQLDVASLDGFGAHSLTSACGAAGALLLYAAATQGQQLRHVRSLKVENETEYIGLDPATRRNLELTETLRGTESPTLYSLLDTCCTTMGSRLLRHWLHHPPRASVAAQSRQQAIGALLDAPANASLDALRSALRQIADVERITGRLALLSARPRDLSSLRDTFAALPALRERISAIVANADALARVDAALAPPAECLDLLTSAIATEPAAMVRDGGVIARGYDAELDELRDISENCGQFLIDLEARERARTGIANLRVEYNKVHGFYIEVTRGQTDKVPDDYRRRQTLKNAERYITPELKTFEDKALSAQERALARERALYDSVLQALLPFIPECQRVASALAELDLLAAFAERARALDWVAPTFTDEIGIEIEQGRHPVVEAQVEQFIANDCRFGPERKLLLITGPNMGGKSTFMRQTALIALMAYVGSYVPAKSACFGPIDRIFTRIGAADDLAGGRSTFMVEMTEAAAILNDATPQSLVLMDEIGRGTSTFDGLALAWAIARHLLAHNACYTLFATHYFELTQLPAEFPQAANVHLSAVEHGHGIVFLHAVNEGPANQSYGLQVAQLAGVPAPVIRAARKHLAYLEQQSASQHTPQLDLFSAPPAAIDDLECADAPALPDTPHPALEKLRDIDPDDLKPREALDLLYELRTLVRSHDADGHA
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: UBAP2_MOUSE
Sequence: MMTSVSNDRCRGAREKPQMPTAHAAQSQKQVVQATAEQMRLAQVIFDKNDSDFEAKVKQLMEVTGKNQDECIVALHDCNGDVNKAINILLEGNSDTTSWETVGGKKKNFGRESSENKENREKRTEREASRGRGTNNRKGRGGNRVREFKGEENGIDCSQGDKPAERGKRARGRGFGRGRGRGTGRFSAQSMGTFNPADYSESMSTDGCGTKLAVWEAAQNGTDEGPEGLAKSHSMSQEPPSKSSYGLKGAWKNSVEEWTTEDWTEDLSETKVFTASSAPAENHVTPGHSIDLVALLHKPAPPTQATEVNSFETSQQQGFGQALVFTNSQHNNQMAPGTANSTSASSYSPQSLSSVLGSGFGELPQSNMVNISNSQILDKLKPPGLSPFPAASSAQQNDTASPPATTAAWDLKPSAPQPSVLSRLDFKSQPEPSPVLSQLSQRQQHQTQAVSVPPPGLESFSSLAKPRESTAGDGPSTVSRLLQLPNMTVENIVSAHQPQPKHIKLPKRRVPPASKVPVSAVEMPGSSDVTGLNVQFGALEFGSEPSLSEFGSAASASENSNQIPISLYPKSLSEPLNASFPMTSAVQSSTYTTSVVTSSTLTSSALSSTSPVTTSSSYDQSSVHTRIAYQSSASPPDSAPGSVANGHGGGRSQHTVDTTSSVPAPKKTDPSALPSVSTLPGPASCTALLPSSAQHTATLPSLTPAAAELSSSPLSQLSSSLSGHQNSMTSAHATRSTSTPHTHASVESTASSAAFSAAATSAPSAPSSGVVLPGSMSTVSSLCLGGTTVSVPSSSTRATALVTSGKAPPNLPQGVPPLLHNQYLVGPGGLLPAYPIYGYDELQMLQSRLPMDYYGIPFAAPTALASRDGNLANNPYSGDVTKFGRGDSASPAPPTTPAQAQQSQSQTHHTAQQPFLNPGLPPGYSYTGLPYYTGVPSAFQYGPTMFVPPTSAKQHGVALSTPPTPFQQASGYGQHAYSTGYDDLTQGTAAGDYTKGGYGGSSQAPNKSTGSGPGKGVSVSSGTGLPDMTGSVYNKTQTFDKQGFHAGTPPPFSLPSALGSTGPLAPAAAPGYAPAPFLHIMPAHQQPHSQLLHHHLQQDAPSGSGQRSQPSSLQPKSQASKPTYGSAPYWTN
What is the function of this protein?
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled nucleotide excision repair (TC-NER) machinery fails to resolve DNA damage.  May promote the degradation of ANXA2.
What are the official names of this protein?
Ubiquitin-associated protein 2, UBAP-2, Protein lingerer homolog 1, mLig-1, RNA polymerase II degradation factor Ubap2.
Protein: YAGB_ECOLI
Sequence: MNKDSTQTWGLKRDITPCFGARLVQEGHRLHFLADRAGFTGSFSEVQTLQLDEAFPHFVAHLELMLLSCELNPRYAHCVTLYRNGLTGEADTLGSHGYVYIAILNRHGFNRHLRVI
What is the function of this protein?
Putative antitoxin component of a type IV toxin-antitoxin (TA) system; its cognate toxin is unknown.
What are the official names of this protein?
Orphan antitoxin YagB.
What is the protein family that this protein belongs to?
Belongs to the CbeA/YafW/YfjZ antitoxin family.
Protein: AQPZ_ECOL6
Sequence: MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRD
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPPK_MYCLE
Sequence: MSRWTHRTFFIALSAIVTTAGFGSSGCAHGNSSTSESAVPSTFPGISSSITAPPATGLPAPEVLTNVLSRLADPNIPGIDKLPLIESATPDSAVTLDKFSNALRDNGYLPMTFTANNIAWSNKNPSDVLATISVNIAQTNNSVFSFPMEFTPFPPPQQSWQLSKRTADMLLEFGNSSGLTNPAPIKAPTPTPSH
What are the official names of this protein?
Putative lipoprotein LppK.
What is the protein family that this protein belongs to?
Belongs to the MTB12 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: COAD_ECOSM
Sequence: MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VCL_VICFA
Sequence: MAATTLKDSFPLLTLLGIAFLASVCLSSRSDQDNPFVFESNRFQTLFENENGHIRLLQKFDQHSKLLENLQNYRLLEYKSKPHTIFLPQQTDADFILVVLSGKAILTVLLPNDRNSFSLERGDTIKLPAGTIGYLVNRDDEEDLRVLDLVIPVNRPGEPQSFLLSGNQNQPSILSGFSKNILEASFNTDYKEIEKVLLEEHGKEKYHRRGLKDRRQRGQEENVIVKISRKQIEELNKNAKSSSKKSTSSESEPFNLRSREPIYSNKFGKFFEITPKRNPQLQDLNIFVNYVEINEGSLLLPHYNSRAIVIVTVNEGKGDFELVGQRNENQQGLREEYDEEKEQGEEEIRKQVQNYKAKLSPGDVLVIPAGYPVAIKASSNLNLVGFGINAENNQRYFLAGEEDNVISQIHKPVKELAFPGSAQEVDTLLENQKQSHFANAQPRERERGSQEIKDHLYSILGSF
What is the function of this protein?
Seed storage protein.
What are the official names of this protein?
Vicilin.
What is the protein family that this protein belongs to?
Belongs to the 7S seed storage protein family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Vacuole. Note=Cotyledonary membrane-bound vacuolar protein bodies.
Protein: RECR_SHEFN
Sequence: MKFSPLVDELIQSLRALPGVGPKSAQRMAFQLLERERKVGLKLADSLQKAMSEVGHCQSCRTFTEQDLCPICSSHRRINTGIICVVETPADVLAIEAGGHFNGRYFVLLGHLSPLDGVGPEELGLALLERHLTSNEVSELILATNPTVEGDATAHFIADMARRHNVVISRIAHGVPVGGELEYVDSTTLALSFNGRIPL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: TNNT_PERAM
Sequence: MSDEEEYSEEEEEVPVDTKPRHSVIVVEEKGDPEFVKRQEQKSSALDEQLKEYIAEWRKQRAKEEEDLKKLKDKQSKRKVMRADEEKRMAERKKQEEERRVREIEEKKQRDIEEKRRRLEEAEKKRQAMMQALKEQKQQKGPNFTIQKKDPSFNMSSAQIERNKTKEQLEEEKKISLSFRIKPLEIENLNVDKLKVKATELWDAIVKLETEKYDLEERQKRQDYDLKELKERQKQQLRHKALKKGLDPEALTGKYPPKIQVASKYERRVDTRSYDDKKKLFEGGWATLSSESNEKVWKSKYELFANRSKSKLPKWFGERPGKKKGDPESPEEEEVKADAGVDDELEEPTFEPEPEPEPEEEAAEEEAEEEEEEEEEEEEEEEEE
What is the function of this protein?
Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin T, TnT.
What is the protein family that this protein belongs to?
Belongs to the troponin T family.