PharMolix/UniProtQA huggingface dataset:
Protein: TRAB_PENCR
Sequence: MEDFKVKLVELVSITGGLIVLFIAYTGFRTVYNASFNRLRHIPGPWINSVSMIPYARHMLAGTTVENSVRLHEKYGDVVRISPNEVSFISGETAFPDIYGFRTGKLKGHLNMEKDPVWYVKPSNGSPSLLQANDEDHARGRRVLSHAFSERAVAAQEPLVQTYVDQLINGLKGATAEKEGEGVVDMVSWYNWTTFDIIADLMFGEPFGCLQDLSTHKYVAVLLESFKSLRILYVLAHFPWLKYFGNLFLDQRQVQKRKDHLSWVSTQVQKRRDRETTRPDFMTLILANNGNKGSKLTDEEINSNAFLLLNAGSETTATLLSAVTFLLLKNPRVMEKLKQEIREKFASYEEIQLPTLNTMTYLHAVLLEALRYFPPAPVGFGRVVNRGGEFISGHFLPEGCIVSVSQYAAYHSSRNFKDPDAFVPERWHVPREKEYADDKRSAAQPFSYGPRGCLGRNLAHAELRIILAKMVWSFDLELEERSQDWLSRCKVMRLWVKPELAVKLKKVIR
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the tra gene cluster that produces terrestric acid (PubMed:30811183).  The clavatol biosynthesis cluster cla and the terrestric acid cluster tra are both involved in the production of peniphenones and penilactones (PubMed:30811183).  The non-reducing PKS claF is responsible for the formation of clavatol from successive condensations of 3 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit, and 2 methylation steps (PubMed:30811183).  The esterase claE probably collaborates with claF by catalyzing the hydrolysis of ACP-bound acyl intermediates to free the ACP from stalled intermediates (By similarity).  The clavatol oxidase claD then converts clavatol to hydroxyclavatol (PubMed:30811183).  Spontaneous dehydration of hydroxyclavatol leads to the accumulation of the highly active ortho-quinone methide (PubMed:30811183, PubMed:31860310).  On the other hand, the PKS-NRPS hybrid traA is involved in the formation of crustosic acid, with the help of traB and traD (PubMed:30811183).  The polyketide synthase module (PKS) of traA is responsible for the synthesis of the polyketide backbone via the condensation of an acetyl-CoA starter unit with 3 malonyl-CoA units (PubMed:30811183).  The downstream nonribosomal peptide synthetase (NRPS) module then amidates the carboxyl end of the polyketide with L-malic acid (PubMed:30811183).  Because traA lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase traG (By similarity).  Crustosic acid undergoes decarboxylation and isomerization to the terrestric acid, catalyzed by the 2-oxoglutarate-dependent dioxygenase traH (PubMed:30811183).  Both acids are further converted to the 2 gamma-butyrolactones (R)-5-methyltetronic acid and (S)-5-carboxylmethyltetronic acid, with involvement of the cytochrome P450 monooxygenase claJ (PubMed:30811183).  Spontaneous addition of the methide to these gamma-butyrolactones leads to peniphenone D and penilactone D, which undergo again stereospecific attacking by methide to give penilactones A and B (PubMed:30811183, PubMed:31860310).
What are the official names of this protein?
Cytochrome P450 monooxygenase traB, Terrestric acid biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: BETA_AGRRK
Sequence: MQADFVIIGSGSAGSAMASRLSEDGKHTVIVLEFGGSDVGPFIQMPAALAWPMSMDRYNWGYLSEPEPQLNNRRITAPRGKVIGGSSSINGMVYVRGHAEDFNRWEELGAQGWAYADVLPYFKRMEHSHGGEEGWRGTDGPLHVRRGDARNPLFHAFIEAGKQAGFEATEDYNGGKQEGFGLMEQTTWMGRRWSAATAYLKPALKRPNVELIRCFARKVVIENGRATGVEIERGGKIEIVKANSEVIVSASSFNSPKLLMLSGIGPGQHLQEMGIEVKIDRPGVGANLQDHMEFYFQQTSLKPVSLYSWLPWYMQGIVGAQWMFFKSGLGTSNQFEACAFLRSAPGVKQPDIQYHFLPVAISYDGKAAAKSHGFQAHVGYNLSKSRGAVTLRSSDPKADPVIRFNYMSHPEDWEKFRHCVRLTREIFGQKAFDDYRGPEIQPGPDVQTDDQIDAFLREHLESAYHPCGTCKMGSKDDPMAVVDPDTRVIGVEGLRVADSSIFPSLTYGNLNGPSIMTGEKAADHILGKPRLARSNQEPWINPRWEVSDR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: KDUI_SALEP
Sequence: MDVRQSIHSEHAKTLDTQALRREFLIENIFVADEYTMVYSHIDRIIVGGIMPVSHSVEIGGEVGKQLGVSRLLDRRELGVINIGGAGAIIVDGQRHDIGHRDALYIGKGAKELVFVSNEASRPAKFYYNCAPAHTAYPTKKVSPADVAPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYLYFNMEEDSCVFHMMGQPQETRHIVMRNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVQDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: RL36_HALOH
Sequence: MKVRPSVKPICDKCKVIRRKGKVRVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RIMM_KINRD
Sequence: MEYVVARVGRPHGVRGEVTVEVRTDDPDTRFAPGAVLRTDPDRGPLTVATARWHNGTLLLTFQGVEDRTAVEGLRNTRLVVDLDDEADPDDDAWYPHQLQGLAAVTTTGTPLGTVKDLLTGGAQDVLVVTGTDGREVLVPFVTPLVPRVDVKRGKVVLSPPGGLFVELPGEPEE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_ACAM1
Sequence: MDVIPAIDLLEGRCVRLYQGDYDQSQVFSENPVEVAKAWEAQGAQWLHLVDLDGAKTGQPVNLDTIAAVVEALEIPVQVGGGLRDRNRVTQLLNLGVRRGILGTVAIENPDLVQELCQEFPDQIVVGIDAREGRVATRGWLETSEILAVDLAKRMVTAGAAAIIYTDIQRDGTLQGPNIPMLREMAEAITIPVIASGGVSSITDLLNLLALEAIGVTGAIVGKALYTEDIALSEALRAVGPGRWQDVPPDLGSSALA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_RICB8
Sequence: MDKVTLKKNLQEKMDKALKVLDHELKGLRTGRASVNLLDSVTVEAYGDRMPLSQVASLTTPDARTINVQVWDKSMVSSVEKAITVANLGLTPSSDGQLIRLPIPALTEERRKELAKLAHKYGEDTKISLRNIRRDGNEELKKMEKDNIIAKDEHHSLAEQVQKLTDEYSSKVDSAIKQKEQEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB3_ORYSJ
Sequence: MSRATAVSRLARAARAAAAARRHHAGGRDPLRALASLAGDASASAGGGARRPAWFAPPMGRLGGGGLLVPPPPPQRRLFHPTQAARYSTSSSSQITPGEFTEMAWEGVVGAVDAARMSKQQVVEAEHLMKALLEQKDGLARRIFSKAGIDNTSVLQATDEFISRQPKVVGDTSGPIIGSSFVSILDNARKHKKEYADEFVSVEHILRAFTEDKRFGQQLFRDLKIGENELKEAISAVRGSQRVTDQNPEGKYQALEKYGIDMTELARRGKLDPVIGRDDEVRRCIQILCRRTKNNPVIIGEPGVGKTAIAEGLAQRIVRGDVPEPLQNRKLISLDMGALLAGAKFQGQFEERLKAVLKEITASNGQIILFIDEIHTIVGAGAAGGAMDAGNLLKPMLGRGELRCIGATTLDEYRKYIEKDAALERRFQQVYCGEPAVEDTISILRGLRERYELHHGVKISDGALVSAAVLSDRYITGRFLPDKAIDLVDEAAAKLKMEITSKPIELDEVDREIIRLEMEKLSLKNDTDKASKQRLSKLEADLESLKQKQKNLSEHWEYEKSLMTRIRSIKEETDRVNLEIEAAEREYDLNRAAELKYGTLLSLQKQLEEAENKLMEFQQSGKSMLREEVTDVDIAEIVSKWTGIPVSNLQQSEKEKLLLLEDVLHKRVIGQDIAVKSVANAIRRSRAGLSDPNRPIASLMFMGPTGVGKTELGKTLAEFLFNTENALIRIDMSEYMEKHAVSRLVGAPPGYIGYGEGGQLTEAVRRRPYSVVLFDEIEKAHQDVFNILLQLLDDGRITDSQGRTVSFTNCVIIMTSNIGSPLILDTLRNTSDSKEAVYEIMKKQVIDMARQSFRPEFLNRIDEYIVFQPLDTTEINRIVEIQLNRVKNRLRQQKIHLQYTPEAVEHLGSLGFDPNYGARPVKRVIQQMVENEIALSVLKGDFKEDDTVLVDVSSVAIAKGLAPQKKLVLQRLENANLELVAND
What is the function of this protein?
Molecular chaperone that may not be involved in heat stress response or tolerance.
What are the official names of this protein?
Chaperone protein ClpB3, mitochondrial, ATP-dependent Clp protease ATP-binding subunit ClpB homolog 3, Casein lytic proteinase B3.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL31_ENCCU
Sequence: MWSKIEENQTVEMTVNLRRICSRLPWTKKASKVVRMLKREIQKHFREEIGVVVTNDLNNFLYSRGIKKIPNKVRVRVTKETSLKNAEENVLKTDLVVVGSFKNLKEVIVDQ
What are the official names of this protein?
60S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: ATPL_GEOUR
Sequence: MSFFTMCVLAAGIGMALGTLGTGIGQGLAVKSAVEGVSRNPGASGKILTTMMIGLAMIESLAIYALVVCLIILFANPYKEIALELAKTVAK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROK_SALG2
Sequence: MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTGADVGWVFDVEGEDGFRNREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQVEAPPREVLEALANERNPLYEEIADVTIRTDDQSAKVVANQIIHMLESN
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 1, SK 1.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAPP1_HUMAN
Sequence: MRLWSWVLHLGLLSAALGCGLAERPRRARRDPRAGRPPRPAAGPATCATRAARGRRASPPPPPPPGGAWEAVRVPRRRQQREARGATEEPSPPSRALYFSGRGEQLRLRADLELPRDAFTLQVWLRAEGGQRSPAVITGLYDKCSYISRDRGWVVGIHTISDQDNKDPRYFFSLKTDRARQVTTINAHRSYLPGQWVYLAATYDGQFMKLYVNGAQVATSGEQVGGIFSPLTQKCKVLMLGGSALNHNYRGYIEHFSLWKVARTQREILSDMETHGAHTALPQLLLQENWDNVKHAWSPMKDGSSPKVEFSNAHGFLLDTSLEPPLCGQTLCDNTEVIASYNQLSSFRQPKVVRYRVVNLYEDDHKNPTVTREQVDFQHHQLAEAFKQYNISWELDVLEVSNSSLRRRLILANCDISKIGDENCDPECNHTLTGHDGGDCRHLRHPAFVKKQHNGVCDMDCNYERFNFDGGECCDPEITNVTQTCFDPDSPHRAYLDVNELKNILKLDGSTHLNIFFAKSSEEELAGVATWPWDKEALMHLGGIVLNPSFYGMPGHTHTMIHEIGHSLGLYHVFRGISEIQSCSDPCMETEPSFETGDLCNDTNPAPKHKSCGDPGPGNDTCGFHSFFNTPYNNFMSYADDDCTDSFTPNQVARMHCYLDLVYQGWQPSRKPAPVALAPQVLGHTTDSVTLEWFPPIDGHFFERELGSACHLCLEGRILVQYASNASSPMPCSPSGHWSPREAEGHPDVEQPCKSSVRTWSPNSAVNPHTVPPACPEPQGCYLELEFLYPLVPESLTIWVTFVSTDWDSSGAVNDIKLLAVSGKNISLGPQNVFCDVPLTIRLWDVGEEVYGIQIYTLDEHLEIDAAMLTSTADTPLCLQCKPLKYKVVRDPPLQMDVASILHLNRKFVDMDLNLGSVYQYWVITISGTEESEPSPAVTYIHGSGYCGDGIIQKDQGEQCDDMNKINGDGCSLFCRQEVSFNCIDEPSRCYFHDGDGVCEEFEQKTSIKDCGVYTPQGFLDQWASNASVSHQDQQCPGWVIIGQPAASQVCRTKVIDLSEGISQHAWYPCTISYPYSQLAQTTFWLRAYFSQPMVAAAVIVHLVTDGTYYGDQKQETISVQLLDTKDQSHDLGLHVLSCRNNPLIIPVVHDLSQPFYHSQAVRVSFSSPLVAISGVALRSFDNFDPVTLSSCQRGETYSPAEQSCVHFACEKTDCPELAVENASLNCSSSDRYHGAQCTVSCRTGYVLQIRRDDELIKSQTGPSVTVTCTEGKWNKQVACEPVDCSIPDHHQVYAASFSCPEGTTFGSQCSFQCRHPAQLKGNNSLLTCMEDGLWSFPEALCELMCLAPPPVPNADLQTARCRENKHKVGSFCKYKCKPGYHVPGSSRKSKKRAFKTQCTQDGSWQEGACVPVTCDPPPPKFHGLYQCTNGFQFNSECRIKCEDSDASQGLGSNVIHCRKDGTWNGSFHVCQEMQGQCSVPNELNSNLKLQCPDGYAIGSECATSCLDHNSESIILPMNVTVRDIPHWLNPTRVERVVCTAGLKWYPHPALIHCVKGCEPFMGDNYCDAINNRAFCNYDGGDCCTSTVKTKKVTPFPMSCDLQGDCACRDPQAQEHSRKDLRGYSHG
What is the function of this protein?
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF.  Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
What are the official names of this protein?
Pappalysin-1, Insulin-like growth factor-dependent IGF-binding protein 4 protease, IGF-dependent IGFBP-4 protease, IGFBP-4ase, Pregnancy-associated plasma protein A, PAPP-A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M43B family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYF1_CANGA
Sequence: MADIDQYILDDSDIAFEYELQKSPSVEVWQRYIAHWEAQVCEDGVRSARHILWLYERMVTQFPTLTVWEQYIGWFRRQYKLDQYLDTFKLYERCINSVKGPLGVFAVEVMLFCISTFDLDIIMKGLQLVLHRCNKDEVERIWNIVLGFALEHVLPSEEGPNNIDFSAFNDRNYEDLRLDIYKLLFLGGDQTEIEDDEEDEDVDKWTASLLRYYLQVANEDKYDETLRLLIRTKDIKIIKECFDLYIFNDKTGKNNRESKKEYDFDLYIYYLDTLDKLRLDKDYKSVFDNLLEKYPQHRVLLTLKLADFHMKRADFDKMEKVLTKALSETVKTNEFIAIYTYHVNFEQAYVETIFDEMRDDPEIQVQKKWKSEMDDHLIILGDLTSRYHLLVNDLKIRQNPNSVSNWLERTTLFEDFDKKCEVFVEAIKTIDPIKVKDKEYGMLGKLWCDYAKVYWSNKSYEEARTIYESATKVPFPDLQDLEIVWHTWAVNEFQIHNIERALKILRKALTVPPSYESIIDRFKSENRRLPSQTILFTSKRLWNYYIDLLESIPTIDANDVIRAYDTLMTLKLITPVGILNYATFLKQNNNLHGSLQVYEKGINMFPPEICYELWTLLLDEVMEPAHQATKERIRELFEQCLQQLGNTDININSIYVKYSDFEIHNKLFSRAIDLLMSGARRPYTNKEQLKQRVDLWESAISKCEEFLGPDSLRQLLSECIQELPNSKAITYVLKFTKLEMSLSDYTRARELLQYGAQLLPPIKNEELWGLWEQFELEHGDKSYYKEMLLLKQKLEKEMKVDTEEVSKGQGNVQFVASSVKNQEAKTNPDEIEIDI
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle progression.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF1.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOH_VIBVU
Sequence: MTTQAYPMALVTQDSLDGYIRSVNSYPMLTADEERDLAERLHYKGEIEAAKGLILSHLRFVVHVARGYSGYGLPMADLVQEGNIGLMKAVKRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKIATTKAQRKLFFNLRKSKKRLGWFNNGEVETVARELGVEPAEVREMESRLAAVDSTFDLPNEEDDSSSVSTAPVLYLEDKSSDVADNLEAQNWEAHTNNRLAMALASLDERSQHIVRSRWLDDDKATLQDLAEMYGVSAERIRQLEKNAMKKLKMAVGEI
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in regulation of expression of heat shock genes.
What are the official names of this protein?
RNA polymerase sigma factor RpoH, RNA polymerase sigma-32 factor.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_LACPL
Sequence: MNIIDDLKWRGAINQQTDEAGLKELTENQSVSLYCGIDPTGDSMHIGHLIPFMILKRFQLAGHHPYVVVGGGTGAIGDPSGKNSERKLQTMDQVKHNQDGLSAQMYKLFGHDENFSIVNNYDWLSKISLLDFLRDYGKLFSVNTMLNKEVVASRLEVGISYTEFTYQILQSVDFLHLYRAEHVQLQIGGADQWGNITAGTDLIHRLEGNDAKAYGLTIPLLLKADGTKFGKTAGGAVWLNPERTSPYEFYQFWINQDDRDVVKYLKYFTFLSHEEIDRLAETVKTAPEKREAQRRLAEEVTEFVHGKQAVVEAENITKALFTGDVQSLTADEIEQGFKGVPSADVSAEKQNIVLWLVDATKFEPSRRQAREDIKNGAIRINGEKVTDVEAEIDPSAAFNGKFVIVRRGKKRYFLAHVK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_METTP
Sequence: MKENIEEAVKKAVSEAPPRGFKESVDLAINLHNIDLTQPGNRVDTEVILPHGRGRPNRIAVFAAGDTALKAKAAGADYVISPEELKLLGENRKNARKLADEYDFFIAETQFMPVIGKTLGPILGKRGKMPTPLPPNADVAQMISRLKNIVRIRSRDRPTFHIAVGRRDMDARQLAENIESVITKLEQTLKDGRRNLKSVYVKTTMGPAVRVI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: SK1_PSEBJ
Sequence: EQFDDYGHMRF
What is the function of this protein?
Myotropic peptide.
What are the official names of this protein?
Sulfakinin-1, PseBi-SK-1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAZ_ECOLC
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: SEPF_STRP3
Sequence: MAFKDTFNKMISYFDTDEVNEVEEDVAASTDNVIPRSQQSVRASSHPKQEPRNNHVQQDHQARSQEQTRSQMHPKHGTSERYYQQSQPKEGHEMVDRRKRMSTSGIANRREQYQQSTCSDQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQFMLDAQARRCLDFIDGASKVLYGSLQKVGSSMYLLAPSNVSVNIEEMTIPHTTQDIGFDFDMKRR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: RSA1_ARATH
Sequence: MHRDMYSSRGTGYGQQQYGSQSGYSQNLGSGYPGSSVSGGAEGGSQISLSSRHPSITGAPQETDIGGGYRSHLSTAASHYGTQYGSVYGSTSLSSSQPLSTNGLGSSVLDNRSGYVPTLPDSPKFASGSYLSPSSHGYGQKTDDLYSDKLSGYIPVDRRQYGEQSSSYLGRELQNEPTRRYADPSNFARQTDLYDRIDQASLLRGEQLLKMQSLHTSSVDAGVNRQTDYLTERSSTVRHSDQEAMHYGGRLESDPHGLSVRNTSSYASQHTPSLLGAVPRRNLDDYIYPESSSNPGYGVSLPPGRDYGTGKGIHSAASLDLDYPGGMLARGTGAAPRVDDLRKGDRASYLREFDLREEERRREDQRARDKEREREREREHDRERERQRERERQRARDRERERILERREKERQGERERERKRALEIKRDRTPTARATSKDTKERTPVPKSISRDARSSSLRRDAHHREASIRRSSPIKPIRRDYVCKVLSSRLVDMERDYVTLDKRYPRLFVPSEFSKVVVNWPKQKLTLSMHTAVSFEHDYIEDGGADVKSTSTKPLALKTGGKSVWNAKMVLMSGLSRTALEDLASDKFFEDRIPHICNILKFAVLKKDHSFMAIGGSWDPTDGMDPSVDQSSLIQTMLRHSKDKLHLDLSNCRHWNPFLEIHYDRVGTDGVFSYKEITVLFVPDLSECLPSFDVWRTQWLAHRKALTERDRLLSQEVKKDTVEVTKDAEKKSPGDTSGTPTTGTKKTVKKIIKRVVKRPVNDGKATGMKGEKSDVPEHVAIPETTVPKEESTGTSSNKKIVKKVAETGDTSDPSAKANEQTPAKTIVKKKIIKRVAKRKVAEIDNKMDGDSKKDGDSDEKKVMEVGKKSSDSGSVEMKPTAESLEDVKDENASKTVDVKQETGSPDTKKKEGASSSSKKDTKTGEDKKAEKKNNSETMSEGKKIDRNNTDEKEVKEKVTEKEIKERGGKDESRIQVKDRKKCEEPPRAGFILQTKRNKDSKLRSLSASLDSLLDYTDKDLDESSFEISLFAESLYEMLQYQMGSRIFEFLKKLRVKIVRQRNQRKRHQEELSVKQNEAKSQDKRQKTAEHEDKEASVISESAPGKDDKETSGKETVDGSREIADKEAVAKTKETLGSKEVTVGEAVNMEVENQDEEDDDGDDDPEEDPEEDPEEDPEEDPEEDPEECEEMDVANTEQEEPAEEPQKKEENLEKTSGTVADPITEAETDNRKEERGPNDSKTEIKPKSETEKHGKQDGGTSDAAKREETVDKELLQAFRFFDRNQAGYVRVEDMRVTIHSLGKFLSHREVKELVQSALLESNTGRDDRILYNKLVRLSL
What is the function of this protein?
Required for salt tolerance and sodium (Na) homeostasis after salt stress.  Together with BHLH148/RITF1, regulates the transcription of several genes involved in the detoxification of reactive oxygen species (ROS) generated by salt (NaCl) stress.  Binds calcium.
What are the official names of this protein?
Protein SHORT ROOT IN SALT MEDIUM 1, AtRSA1, Protein EMBRYO DEFECTIVE 1579.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS10_BEII9
Sequence: MNGQNIRIRLKAFDHRILDTSTKEIVSTAKRTGAQVRGPIPLPTKIEKFTVNRSPHVDKKSREQFEIRTHKRVLDIVDPTPQTVDALMKLDLAAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: NU1C_SOLBU
Sequence: MIIDTTEIETINSFSKLESLKEVYGIIWMLVPIVTLVLGITIGVLVIVWLEREISAGIQQRIGPEYAGPLGILQALADGTKLLLKENLIPSTGDTRLFSIGPSIAVISIFLSYSVIPFGDHLVLADLSIGVFFWIAISSIAPVGLLMSGYGSNNKYSFLGGLRAAAQSISYEIPLALCVLSISLLSNSSSTVDIVEAQSKYGFWGWNLWRQPIGFIVFLISSLAECERLPFDLPEAEEELVAGYQTEYSGIKFGLFYIASYLNLLVSSLFVTVLYLGGWNLSIPYIFVPELFGINKGGKVFGTLIGIFITLAKTYLFLFIPIATRWTLPRLRMDQLLNLGWKFLLPISLGNLLLTTSSQLLSL
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic, NAD(P)H dehydrogenase subunit 1, NDH subunit 1, NADH-plastoquinone oxidoreductase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CP078_HUMAN
Sequence: MSEQQMDLKDLMPTKRKYMWKTAEDRRMSDLTCVLEWLERRQGKKKQAPEKQKPKVVTVLKRNKKKEEKKGKGLMTARGGNRRDTETSQQALGKRFRKDAASYRSLYGVEQKGKHLSMVPGSYIKDGPKKSDTDIKDAVDPESTQRPNPFRRQSIVLDPMLQEGTFNSQRATFIRDWSNKMPDMAYERKLKSLMEKSTEPKMETMRMLKPEEVLSCRYLRLSKENIRTLLKLCKDAGMNVDIHPHMVEEDIDAKKVFTGIPSMAL
What are the official names of this protein?
Uncharacterized protein C16orf78.
Protein: CTHL2_CAPHI
Sequence: METQGASLSLGRWSLWLLLLGLVVPLASAQALSYREAVLRAVGQLNERSSEANLYRLLELDPAPNDEVDPGTRKPVSFTVKETVCPRTTQQPPEECDFKENGLVKQCVGTVTLDPSNDQFDINCNELQSVRFRPPIRRPPIRPPFNPPFRPPVRPPFRPPFRPPFRPPIGPFPGRR
What is the function of this protein?
Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria.  Shows a potent antimicrobial activity against the Gram-negative bacteria E. coli, S. typhimurium and P. aeruginosa.  Less active against the Gram-positive bacteria S. aureus, L. monocytogenes and B. subtilis.
What are the official names of this protein?
Cathelicidin-2, Bactenecin-5, Bac5, ChBac5.
What is the protein family that this protein belongs to?
Belongs to the cathelicidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLC_DICDI
Sequence: MNKILLKRQILYNLPKYFKNNIPYTITINKSNQFINNNCKNNNNNFRKLNFTTTTTTTTTAPITNNKPKSNMLYSPKDRSYEEAVNALLTLQSNQTVIISWTKERRDNKEESAKFLMEEMRNYCKTLSIDLERESIIHVAGTKGKGSTCAITESIIREQGFSTGLFTSPHLISPRERIRINGEMISKEMFSQYFWNCWDLLIKDYQTQLPNFFRYLTLMALKIFQDEAIQCTILEVGIGGRMDSTNVFPKPMVTGISALGYDHQNLLGNTLAEIALEKAGIMKVGIPIFTVSSQLPEAINVLIDHSNKVKSPLSIVPSIDQYTISSGGGNNNNNKIESIGLKGTHQLENASLAIALANCWFKKQTFKDVNEIFNSENHKQYNYETNNYNVTQFTPLLKSIELGLKNCEWAGRAQHFTNPSHFPNMDFYLDGAHTVESSIVMLNWWKSIVNTTTTTTTTTTTTTTNNNDDDTIHILIFNSTGGRNPTSFLTPIIQSIDNKEIPIFNKSIIPNIIIEKPIDKKYYINEIIQSNQSSTATTTPIPDNAAVKQTTEIKESSTWEDFVVECYDKLSKKSHPCITADSIESSIEIAKELSENGTKNVKVLITGSLYLVGGVLKVLLKEKSFN
What is the function of this protein?
Conversion of folates to polyglutamate derivatives.
What are the official names of this protein?
Putative folylpolyglutamate synthase, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolate synthase, Tetrahydrofolylpolyglutamate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
Protein: 3SX2_MICMP
Sequence: MKTLLLTLVVVTIVCLDLGNSLICYVSREGQTQTCPEGMNLCEKYAVSYFHDGRYFFTYECTSTCHRGDRNVCCSTDLCNK
What is the function of this protein?
Snake venom neurotoxin that blocks neuromuscular transmission, presenting a postsynaptic action through the nicotinic acetylcholine receptor (nAChR).  Has no cytotoxic activity.
What are the official names of this protein?
Mipartoxin-2, Mipartoxin-II, Three-finger toxin-03, 3FTx-03.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.