PharMolix/UniProtQA huggingface dataset:
Protein: NUOCD_SERP5
Sequence: MTDSTTHDALPAWQTRDHLDDPVIGELRNRFGPEAFTVQPTRTGMPVVWVKPDQLLEVMTFLRKQPKPYVMLFDLHGVDERLRTHRDGLPAADFSVFYHLISIERNRDIMLKVALSEKDLHVPTATKVFPNANWYERETWEMFGITFDGHPHLSRIMMPQTWEGHPLRKDYPARATEFDPFVLTKQKEDLEMEALTFKPEDWGMKRGTENEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGIKVPDRVDTIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYVKAALKNSILKGRSVGVASYNAKEALEWGVTGAGLRATGIEFDVRKWRPYSGYENFDFEVPVGDGNSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPAVIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PSBM_PROM2
Sequence: METTNFGFVASLLFVGVPTIFLIGLFLSTQEGEKSSFYSDSGKGKLDPKR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PE11A_LITPE
Sequence: DAQEKRQPWLPFG
What is the function of this protein?
Induces contraction of intestinal smooth muscle in isolated guinea pig ileum.
What are the official names of this protein?
Peroniin-1.1a.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Peroniin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PURT_PSEU2
Sequence: MTQIGTPLSPTATRVLFCGSGELGKEVVIELQRLGVEVIAVDRYENAPAMQVAHRSHVINMLDGAALRAVIEAEKPHFIVPEIEAIATATLVELEAEGFTVIPTARAAQLTMNREGIRRLAAEELKLPTSPYHFADTFEAYSKAVEDLGFPCVVKPVMSSSGKGQSLLKSTDDVQKAWDYAQEGGRAGKGRVIVEGFIDFDYEITLLTVRHIGGTTFCAPVGHRQEKGDYQESWQPQAMSPVALAESERVAKAVTEALGGRGMFGVELFIKGDQVWFSEVSPRPHDTGLVTLISQDLSQFALHARAILGLPIPLIRQFGPSASAVILVEGQSTQTAFANLGAALAEPDTALRLFGKPEVNGQRRMGVALARDESIEAARAKATRASQAVNVEL
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: NAPA_CAMJ8
Sequence: MNRRDFIKNTAIASAASVAGLSVPSSMLGAQEEDWKWDKAVCRFCGTGCGIMIARKDGKIVATKGDPAAPVNRGLNCIKGYFNAKIMYGEDRLVMPLLRMNEKGEFDKKGKFQQVSWQRAFDEMEKQFKKAYNELGVTGIGIFGSGQYTIQEGYAALKLAKAGFRTNNIDPNARHCMASAVVGFMQTFGVDEPSGCYDDIELTDTIITWGANMAEMHPILWSRVSDRKLSNLDKVKVVNLSTFSNRTSNIADIEIIFKPNTDLAIWNYIAREIVYNHPEAMDMKFIKDHCVFATGYADIGYGMRNNPNHPKFKESEKDTVEKENVITLDDEEATSLSYLGVKAGDKFEMKHQGVADKNWEISFEEFKKGLAPYTLEYTAKVAKGDDNESLEDFKKKLQELANLYIEKNRKVVSFWTMGFNQHTRGSWVNEQAYMVHFLLGKQAKPGSGAFSLTGQPSACGTAREVGTFSHRLPADMVVANPKHREISEKIWKVPAKTINPKPGSPYLNIMRDLEDGKIKFAWVQVNNPWQNTANANHWIAAAREMDNFIVVSDCYPGISAKVADLILPSAMIYEKWGAYGNAERRTQHWKQQVLPVGAAMSDTWQILEFAKRFKLKEVWKEQKVDNKLTLPSVLEEAKAMGYSEDDTLFDVLFANKEAKSFNPNDAIAKGFDNTDVKGDERKIQGSDGKEFAGYGFFVQKYLWEEYRKFGLGHGHDLADFDTYHKVRGLRWPVVNGKETQWRFNTKFDYYAKKAAPNSDFAFYGDFNKMLTNGDLIAPKDEKEHSIKNKAKIFFRPFMKAPERPSKEYPFWLATGRVLEHWHSGTMTMRVPELYRAVPEALCYMSEKDGEKLGLNQGDLVWVESRRGKVKARVDMRGRNKPPVGLVYVPWFDENVYINKVTLDATCPLSKQTDFKKCAVKIYKA
What is the function of this protein?
Catalytic subunit of the periplasmic nitrate reductase complex NapAB.  Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
What are the official names of this protein?
Periplasmic nitrate reductase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: MGTE_ENTFA
Sequence: MNEGQEMEEQFALLLETLKNQQMNEFRELFLALHIYEQGQFYQSLDEKDRQHLYNYLSPKELADMFDVIEEDNENMKDYLAEMRPSYAADMLAEMYTDNAVDLLNMLDKSQKAKYLSLLSSEEAGEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMYVLKNQADMAETIYYVYVVDQENHLVGVISLRDLIVNDDDTLIADILNERVISVHVGDDQEDVAQTIRDYDFLAVPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVDVEEVSENPLKAASKRLPWLITLLFLGMSTASLISNYESLVSEASILAVFISLITGTAGNAGTQSLAVAVRRLAMKDEKDSNFGRLILSEVLTGLVTGAVTGLTIMIVVGVWQHNLPLGFVIGMAMLCAITVANLAGSLIPMLMDKLGFDPAVASGPFITTLSDLTSVLIYFNIASMFMRYFV
What is the function of this protein?
Acts as a magnesium transporter.
What are the official names of this protein?
Magnesium transporter MgtE.
What is the protein family that this protein belongs to?
Belongs to the SLC41A transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPG_STRPS
Sequence: MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQVYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAVMELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTVEMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREEILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAAITQEITEIVAGASALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CATA_RAT
Sequence: MADSRDPASDQMKQWKEQRAPQKPDVLTTGGGNPIGDKLNIMTAGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEHIGKRTPIAVRFSTVAGESGSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDAMLFPSFIHSQKRNPQTHLKDPDMVWDFWSLCPESLHQVTFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQGIKNLPVEEAGRLAQEDPDYGLRDLFNAIASGNYPSWTFYIQVMTFKEAETFPFNPFDLTKVWPHKDYPLIPVGKLVLNRNPANYFAEVEQMAFDPSNMPPGIEPSPDKMLQGRLFAYPDTHRHRLGPNYLQIPVNCPYRARVANYQRDGPMCMHDNQGGAPNYYPNSFSAPEQQGSALEHHSQCSADVKRFNSANEDNVTQVRTFYTKVLNEEERKRLCENIANHLKDAQLFIQRKAVKNFTDVHPDYGARVQALLDQYNSQKPKNAIHTYVQAGSHIAAKGKANL
What is the function of this protein?
Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide.  Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: CATA1_RICCO
Sequence: MDPYRNRPSSGFNTPFWTTNSGAPVWNNNSSLTVGSRGPILLEDYHLIEKLANFDRERIPERVVHARGASAKGFFEVTHDVSHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFIRDGMKFPDVVHAFKPNPKSHLQENWRIFDFLSHVPESLHMLTFLLDDLGIPQDYRHMEGSGVNTYTLINKAGKVHYVKFHWKPTCGVKCLLENEAIKVGGSNHSHATQDLYDSISAGNYPEWKLYIQIMDPAHEDKFDFDPLDVTKTWPEDILPLQPVGRLVLNKNIDNFFAENEQLAFCPGIVVPGVSYSEDKLLQTRIFSYSDTQRHRLGPNYLQLPVNAPKCAHHNNHHEGFMNFMHRDEEVNYFPSRCDPARNAESFPVPSAICSGKREKCVIEKENNFKQPGERYRSWAPDRQERFLNRLVGGLSDPRITHELRTIWISYWIQCDKSLGQKLATRLNVKPSI
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: PLMP_GRIFR
Sequence: MFSSVMVALVSLAVAVSANPGLSLKVSGPEAVDGVNNLKVVTTITNTGDETLKLLNDPRGALHTMPTDTFAITNESGETPSFIGVKVKYVPSMAAKSTGENVFAVIAPGQSVNVEHDLSAAYNFTSSGAGTYALEALNVFNYIDPETNEPVEIWADAEAHTTAVSGKLAVVRATPTLTRPVTYNGCSSSEQSALAAAASAAQSYVAESLSYLQTHTAATPRYTTWFGSYISSRHSTVLQHYTDMNSNDFSSYSFDCTCTAAGTFAYVYPNRFGTVYLCGAFWKAPTTGTDSQAGTLVHESSHFTRNGGTKDYAYGQAAAKSLATMDPDKAVMNADNHEYFSENNPAQS
What are the official names of this protein?
Peptidyl-Lys metalloendopeptidase, MEP, GfMEP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
What are the subcellular locations of this protein?
Secreted. Note=Binds strongly to beta-1,3-glucan and chitin, major polysaccharides constituting the fungal cell wall.
Protein: RNY_BACAN
Sequence: MSSTVWILISILLATVGAVVGFFVRKSIAEAKINGAANEAKRILDEANREAEALKKEALLEAKDEIHTLRTEAELEIRDRRSELQKQENRLMQKEENLDRKDETLDKRELQLEKKEDSLVARQQQIEELESKVGELVQKQQTELERISNLTREQAKAIILGKVESEVSHEIAVMVKESEVRAKEEADKKAKEILSLAMQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRRETARIALDKLVQDGRIHPARIEEMVEKSRREVDEYIREVGEQTTFEVGVHGLHPDLIKILGRLKYRTSYGQNVLKHSMEVAYLTGLMAAELGEDEKLARRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINSIASHHGDTEPTSIIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYEGVEKSFAIQAGREVRILVKPDTIDDLEAHRLARDIRKRIENELDYPGHIKVTVIRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: UPPP_STRPS
Sequence: MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYIGLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTH_SALA4
Sequence: MAIKLIVGLANPGAEYAATRHNAGAWYVDLLAERLRAPLREEPKFFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGAMASFYRIQPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTELWFKEGLAKATSRLHTFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_OLEA2
Sequence: MARIAGVDLPRGKRVDIALTYIYGVGRATALEILDTTGVDWTRNIDDLSADEVNEIRKEIEQNHKVEGDLRREISSNIKRLMDIGCHRGLRHRRGLPARGQRTKTNARTRKGPRRGVAGKRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: PUR9_LEUMM
Sequence: MTRALLSVSDKSGLIPFAKNLVELGYELVSTGGTHKVLIDAGLDVISIDEVTDFPEMLDGRVKTLHPRVHAGLLARRDLPEHMAKLAEFDITPIDMVVVNLYPFKSTIQKEGVTEAEAIENIDIGGPSMLRSAAKNFASVLPIVDPKDYDVVVNKLKAGEVDREYRKSLAAKVFQHTASYDALIANYLTETSFPENLTLAYEKFDDMRYGENPHQPAAAYKTALPEAYSVLNADILHGKQLSYNNIRDADAALRIIAEYEETTVVTVKHMNPAGIGQGQTLEAAWDQAFAADDISIFGGIVALNREVDAATAEKMHDIFLEIIIAPSFTPEAYEILAAKKNLRLLTLPFTTSIPQKLEVTSVLGGVVVQERDLVGESENNFTVVSKAQPTKEQLQAMVFAQKVVKHVKSNAIVVARNGQTLGIGAGQPNRIDSVVYSIQKAEKKPGFDEAVLASDAFFPMDDSVQYAAEHGIKAIVEPGGSIKDKDSIAKADELGVVLIFSGTRHFKH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: ARAF_RAT
Sequence: MEPPRGPPASGAEPSRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCVVYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLFHGFRCQTCGYKFHQHCSSKVPTVCVDMSTNRRQFYHSIQDLSGGSRQQEVPSNLSVNELLTPQGPSPFTQQRDQEHFSFPAPANPPLQRIRSTSTPNVHMVSTTAPMDSSLMQFTAQSFSTDAAGRGGDGAPRGSPSPASVSSGRKSPHSKLPAEQRERKSLADEKKKVKNLGYRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVAQPTAEQAQAFKNEMQVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQGMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAAEVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGSRDQIIFMVGRGYLSPDLSKIFSNCPKAMRRLLTDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELPACLLSAARLVP
What is the function of this protein?
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus.  May also regulate the TOR signaling cascade (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase A-Raf, Proto-oncogene A-Raf, Proto-oncogene A-Raf-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
Protein: GRIP1_HUMAN
Sequence: MIAVSFKCRCQILRRLTKDESPYTKSASQTKPPDGALAVRRQSIPEEFKGSTVVELMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVGERVVLEVEYELPPVSVQGSSVIFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEAALLIEYDVSVMDSVATASGPLLVEVAKTPGASLGVALTTSMCCNKQVIVIDKIKSASIADRCGALHVGDHILSIDGTSMEYCTLAEATQFLANTTDQVKLEILPHHQTRLALKGPDHVKIQRSDRQLTWDSWASNHSSLHTNHHYNTYHPDHCRVPALTFPKAPPPNSPPALVSSSFSPTSMSAYSLSSLNMGTLPRSLYSTSPRGTMMRRRLKKKDFKSSLSLASSTVGLAGQVVHTETTEVVLTADPVTGFGIQLQGSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEASQLLRDSSITSKVTLEIEFDVAESVIPSSGTFHVKLPKKHNVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDNCSMEDAVQILQQCEDLVKLKIRKDEDNSDEQESSGAIIYTVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQMAGETVTLKIKKQTDAQSASSPKKFPISSHLSDLGDVEEDSSPAQKPGKLSDMYPSTVPSVDSAVDSWDGSAIDTSYGTQGTSFQASGYNFNTYDWRSPKQRGSLSPVTKPRSQTYPDVGLSYEDWDRSTASGFAGAADSAETEQEENFWSQALEDLETCGQSGILRELEEKADRRVSLRNMTLLATIMSGSTMSLNHEAPTPRSQLGRQASFQERSSSRPHYSQTTRSNTLPSDVGRKSVTLRKMKQEIKEIMSPTPVELHKVTLYKDSDMEDFGFSVADGLLEKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISRNPLASQKSIDQQSLPGDWSEQNSAFFQQPSHGGNLETREPTNTL
What is the function of this protein?
May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons (PubMed:10197531).  Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).
What are the official names of this protein?
Glutamate receptor-interacting protein 1, GRIP-1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Perikaryon. Cell projection, dendrite. Cytoplasm. Endomembrane system; Peripheral membrane protein. Postsynaptic cell membrane. Postsynaptic density. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in postsynaptic plasma membrane and postsynaptic densities.
Protein: PYRF_HELPS
Sequence: MQLCVALDLEKKEDNLSLLQELKGLDLWAKVGLRSFIRDGAVFLDEIRKIDGNFKIFLDLKLYDIPYTMANAALECAKLEVDMLTVHLSSAKSALTILMQRLNALKKRPLIMGVSALTSFSEEEFLSVYNAPLKTQAIKLSVMGKESGIDGVVCSVFESLAIKEALGKDFLTLTPGIRLNKNDKEDQERVANAKEAKQNLSDFIVVGRPIYQAKEPREVVLELLKDC
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: UVRB_AYWBP
Sequence: MSLTNLFKLQSSLKPSGDQPQAIQKLVNNFKQGLKEQILLGATGTGKTFTIANIIQHLQQKTLVIAHNKTLAGQLYNELKAMFPNNRVEYFISYYDYYQPEAYVASSDTYIEKDSKINDEIDQLRHSAAGSLINRDDVIVVASVSCIYGVGDLKDYQKSTLHLQIGDKYERKNLINKLIELKYQRNEINFQRGTFRVRGDIIEIIASSSKEIGIRIIFFGNEIENIQNFYVLNGKAIANLKLITLFPASLYATNNQKLQESIKRIRQELKEQINHFEKTNQLLAAQKIKMRTLHDLEMLEQIGNCNGVENYSRHLALKGKGEAPSTLIDFFGNDFLTIVDESHVTIPQIKGMYFGDFSRKNNLVNFGFRLPSALDNRPLKFNEFQEKMNKVIYLSATPGDYELTKKIPIVEQIIRPTFVLDPEIEVRPTNNQMDDLYFEIKHQTKNNQRILITTLTINMSEDLTTYLKNLGIKVAYLHSEIKSLQRLEILKDLRLGKYDCLVGVNLLREGLDLPEVALVAILDADKQGFLRNERSLIQTIGRAARNITGKAIMYADCISPAMQIAIEETYRRRKIQKQYNETMKVTPTALNKTILETISIKQKERIKNEKGKSKVQKKLQINTNMTAKNKEIKRLQKTMKEAAKALDFEKAATLRDLILDLEKKEKR
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_LIMRJ
Sequence: MSEKQTPVKELTLQEAQDEIKPLRAKLTKWGKEYYEQDNPTVEDHVYDRAYQRLVQLEEQFPQLVSADSPTQRVGGATESQLTKVRHEIPMLSMGDVFSIEELMDFNQRQQENRDVEVEPEYNLELKIDGLSLSLVYENGKLVQGSTRGNGTIGEDVTANVRTIKSVPAELPEPLSIEVRGECYMPKAAFAKLNAKREAEGLPVFANPRNAAAGSLRQLDPKVTAQRELDTFMYYVPEYQKIGVKTQAEALDRMRELGFNVNPNNRVVHNRDEIEKYIEEYTAQRDKLTYGIDGIVEKVNDLDTEVALGNTVKVPRWEIAYKFPPEEQATIVRDIVWTVGRTGNVTPTAVMDPVQLAGTTVSRASLHNPDYLREKDIRIGDTVYLHKAGDIIPEISKVDLTKRPADSVEYEIPTKCPVCGSELVHLDGEVALRCINPMCPAQIKEGLAHFASRNAMNIDGLGPRIIEQLWDKELIHDVAGLYRLNHDQLLTLDKFGEKSTANLLTSIDNSRNNSVERLLFGLGIRHVGAKAARIIMEHFGDLDSLMKADADEISAISGIGPTIGESIVTYFANQQVVKLIDELREVGVNFAYLGSRSNANPDSEWNGRRVVLTGKLTEMTRGEAKSWLENHGAKVTESVSKKTDIVIAGADAGSKLTKAQNLGIDVWNEQQFSQAMKEEQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PSBU_GLOC7
Sequence: MKTLARILVVFTLIVGLIGFFNPLPAQAALNAVDAKLTTEFGQKIDLNNSHIREFRDLRGFYPNLASKIIKNAPYDKVEDVLNIPGLSERQQERLQANLDKFTVTEPSKELIEGDDRINPGVY
What is the function of this protein?
Stabilizes the structure of photosystem II oxygen-evolving complex (OEC), the ion environment of oxygen evolution and protects the OEC against heat-induced inactivation.
What are the official names of this protein?
Photosystem II 12 kDa extrinsic protein, PS II complex 12 kDa extrinsic protein, PSII-U.
What is the protein family that this protein belongs to?
Belongs to the PsbU family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the Lumenal side of the thylakoid membrane.
Protein: PROB_RHOPB
Sequence: MHRPELKNFRRIVVKVGSSLLIDSEAGEVKAAWLAALAADIAELHLHGRDVLIVSSGSIALGRSRLKLARGPLKLEESQAAAAVGQIALARIWSEVLGDHGIGAGQILVTLQDTEERRRYLNARSTIGKLLEWRAVPVINENDTVATAEIRYGDNDRLAARVATMSSADLLILLSDIDGLYDAPPGANPDAKLIPVVEQVTAEIEAMAGGAESELSRGGMRTKIEAAKIATTAGTHMLIASGKIDHPLRAIANGGACTWFLTPANPVTARKRWIAGSLEPKGTLTIDAGAVTALRAGKSLLPAGVIRVDGHFARGDAVVVRGPDTDEIGRGLVAYDADDADRIKGHSSPDVMSILGITGRAEMIHRDDLVMGAVPG
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IBBB2_HYAOR
Sequence: EQRPLCNECFICDRSGDPRCLCEDHVPQCHEGCHQCEKVDTRSGTTMYQCRSFEYYDCAN
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Bowman-Birk type proteinase inhibitor B2, HOSPI-B2.
What is the protein family that this protein belongs to?
Belongs to the Bowman-Birk serine protease inhibitor family.
Protein: YI168_YEAST
Sequence: MEMTYYEKTPLIRQFLNNGKTNSWFYVKHEMLQPGGSFKSRGIGHLIRKSNEEALSEGSGKLAVFSSSGGNAGLAAATACRSMALNCSVVVPKTTKPRMVKKIQSAGAKVIIHGDHWGEADEYLRHE
What are the official names of this protein?
Putative truncated L-serine dehydratase YIL168W.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU_BEUC1
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAISKVLHDKYPDLNPFTPFDEIDKAPEEKQRGITINIAHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMAQTREHVLLARQVGVPYLLVALNKSDMVDDEEILELVEMEVRELLSSQGFDGDDAPVIRVSGLKALEGDPEWVKTVEELMDAVDESVPEPVRDMDKPFLMPIEDVFTITGRGTVVTGKVERGKLAINSEVEIVGIRPAQKTTVTGIEMFHKQMDEAWAGENCGLLLRGTKREDVERGQVVVKPGTNTPHTQFEAQVYILSKAEGGRDNPFYSNYRPQFYFRTTDVTGVITLPEGTQMVMPGDNTEMTVDLIQPIAMEEGLGFAIREGGRTIGSGKVTKILA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_CAMLR
Sequence: MKVMVIQGPNINMLGVRETHIYGNMKMEDIHEQMKQAAKQANVEIEFFQSNFEGELVDKIQECLGSVDGVIINAAAYAHTSIAIRDAITAINMPVIEVHISNTYRREEFRQKSMIAPVCAGSVVGFGPFGYHMALMGLFQIFDQINAYKAAQAKAQQANQ
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.