PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_RICCK
Sequence: MNNNIMNLIAAIVLSLSIIFGWQYFVVKPEHKKQQQQIAMQKAENLKKQKLKALIKPASDLVVQEANQVQRIKIESESLTGSISLKGLRFDDLILKKYKQDLSKNSTEVRLFSPANTENAYFAEIGLVSNLSSVKLPNNDTIWNSDGEILSPEKPVNLFWVNEDGVKFLVTITLDENYLFTVEQTIVNNSDKELPVQSYGLINRKYIAVEKAVNILHQGPIGCINENLKEYSYDDIKDKKSEKFVASKVDWIGMTDKYWLSSLIPDKSSNYSSNFNYALTQGVERYQVDFISPVQIIKSGENFSITSRIFAGAKKVDLLDKYEKQYGIKLFDRAIDFGWFYIITKPVFYAMNFFYGYVGNFGISILIVTVIIKLLMFTLANKSYCSMKKMKNLQPEIDRIKNLYGDDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAPFYGWIKDLSAPDPTTIFNLFGFLPFSPPSFLMIGAWPILMAITMFLQQRMSPEPADPVQAQVMKFMPLIFLVMFSSFPVGLLIYWSWNNILSIIQQYYINKFN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DBP8_PHANO
Sequence: MANDYPSSDEEIMEAQTGSRKRRKTSSDSESDTAPRAPTATSISRVKPAKDRAGHQAASRVAVSKASVPEENGKEKVSFASIDVAPWLVASLASMEIKRPTGIQKACIPEILKGRDCIGGSRTGTGKTVAFSVPILQKWAEDPSGIFGLIITPTRELAIQIYEQVKAISAPQSMKPILVTGGSDQREQAIALASRPHVVIATPGRLAEHIKTSGEDTICGLRRVRFVVFDEADRLLAPGRGSMIPDIETCLSVLPPKEQRQTLLFTATVTPEVLALKSQPRAPGRLPIFVCEVDTETLATPASLSQLYLQTPVTHKECYLHVLLLTPLNLTKSVIIFCNRTKTATLLEYMLRMLDHRVTALHSGLKQQDRISNLARFRAQAARILVATDVAARGLDIPEVGLVVNFDVPRDPDDYIHRVGRTARAGRPGNSVTFIGQRDVELVLAIEERVGGKMSEFEEEGVSVEGRVVRDALKIVTEKKREALLNIEEGRDVKGNRMVGMKKRRVVE
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: FA96A_DICDI
Sequence: MIMNYNVIDKIDVFDIIRHIKDPEFPKTLEELKVVNEDWITVIDNNDINDSDDINNNNNENYKGYCFIKILFQPTVPHCHLAPTIALCIREKIKEYLPKRSKIEIYIKKGTHQTEDEINKQINDKERIIAALENPEIFQLVKKCIKEDDY
What is the function of this protein?
May play a role in chromosome segregation through establishment of sister chromatid cohesion.
What are the official names of this protein?
MIP18 family protein FAM96A.
What is the protein family that this protein belongs to?
Belongs to the MIP18 family.
Protein: NLAL1_ARATH
Sequence: MRPPMRGGGGFRGRGGRDGGGGGRFGGGGGRFGGGGGRFGGGGGRFGGFRDEGPPSEVVEVATFVHACEGDAVTKLSQEKIPHFNAPIYLENKTQIGKVDEIFGPINESLFSIKMMEGIVATSYSPGDKFFIDPYKLLPLARFLPQPKGQSTGGRGGAGRGRGDSRGRGRGGSFSRGRGAPRGGRFPPRGGSRGSFRGRGRF
What is the function of this protein?
Required for ribosome biogenesis.  Part of a complex which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
What are the official names of this protein?
Putative H/ACA ribonucleoprotein complex subunit 1-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: M28P2_PYRTR
Sequence: MLFRSALLSNVLLLPACAHDVLFSRDLPLPIAANAESYTDCANAAWPPSNVGVELVPQPPDDELRAMVDEMSAENIEATITKLVSFGTRHTLSTFNSSTRGINAARDWIASEMRKYAAESNGTMTVEVQSYVQGVASRIPFPVTISNVLAKATGSEDPSRVYVMTGHYDSRVTDVLNYESDAPGANDDASGTAIAMELARVLAKHQPKSTIILGAVSGEEQGLYGSTYLAQTLKNTSTNVEGMLNCDIVGSSTGDRGQKDPFTIRAFAQGPPPLSAESSAKAAQRLQIGGENDSPARELARFSAEVAANNATGMKVAIIYRLDRFLRGGDHTGFLQAGYPAIRYTEPNENFAHQHQDIRTENGTVYGDLIEFVDFDFTARVGKVNLATLWSLAQAPAMPRNVTIDATILDNESRIKWIISNSTDVASYEVVWRSTIASLWTHMLDVGKVGYVVLPLSKDNVIFGIRAVGKNGYKSPAVYPFPG
What are the official names of this protein?
Probable zinc metalloprotease PTRG_04977.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ITI1_LAGSI
Sequence: QRRCPRIYMECKHDSDCLADCVCLEHGICG
What is the function of this protein?
Strong inhibitors of trypsin.
What are the official names of this protein?
Trypsin inhibitor 1, LLDTI-I, LLTI-I, Trypsin inhibitor I.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I7 (squash-type serine protease inhibitor) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS16_SORC5
Sequence: MAVHIRLARAGTKKTPFYRIVVADQRSPRGGRFIERLGTYDPRRTEIRLDVPRVRHWISNGAQPTHTVALLLKHPGLAQAAAPADAAK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TBA_TYRPU
Sequence: MRECISVHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGTGDDSFNTFFSETGSGKHVPRAVYVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDVVLDRIRKLSDQCTGLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAVYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVELTEFQTNLVPYPRIHFPLVTYSPVISAEKAYHEQLTVAEITNTCFEPQNQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAGIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGLDSTEAEGGDGEEF
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain, Alpha-tubulin.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PGPS1_HUMAN
Sequence: MAVAAAAAAGPVFWRRLLGLLPGRPGLAALLGRLSDRLGRNRDRQRRRSPWLLLAPLLSPAVPQVTSPPCCLCPEGVHRFQWIRNLVPEFGVSSSHVRVLSSPAEFFELMKGQIRVAKRRVVMASLYLGTGPLEQELVDCLESTLEKSLQAKFPSNLKVSILLDFTRGSRGRKNSRTMLLPLLRRFPEQVRVSLFHTPHLRGLLRLLIPERFNETIGLQHIKVYLFDNSVILSGANLSDSYFTNRQDRYVFLQDCAEIADFFTELVDAVGDVSLQLQGDDTVQVVDGMVHPYKGDRAEYCKAANKRVMDVINSARTRQQMLHAQTFHSNSLLTQEDAAAAGDRRPAPDTWIYPLIQMKPFEIQIDEIVTETLLTEAERGAKVYLTTGYFNLTQAYMDLVLGTRAEYQILLASPEVNGFFGAKGVAGAIPAAYVHIERQFFSEVCSLGQQERVQLQEYWRRGWTFHAKGLWLYLAGSSLPCLTLIGSPNFGYRSVHRDLEAQIAIVTENQALQQQLHQEQEQLYLRSGVVSSATFEQPSRQVKLWVKMVTPLIKNFF
What is the function of this protein?
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial, Phosphatidylglycerophosphate synthase 1, PGP synthase 1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GNTP_ECO57
Sequence: MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGMDLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQLSVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQPGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVDMNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSHGNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLATAAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA
What is the function of this protein?
High-affinity gluconate transporter with fairly broad specificity, including low affinity for glucuronate, several disaccharides, and some hexoses, but not glucose.
What are the official names of this protein?
High-affinity gluconate transporter, Gluconate permease 3, Gnt-III system.
What is the protein family that this protein belongs to?
Belongs to the GntP permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRUB1_HUMAN
Sequence: MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAALATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTLDSAARGVLVVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQPPFFTLDVECGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALPEDKWTIDDIAQSLEHCSSLFPAELALKKSKPESNEQVLSCEYITLNEPKREDDVIKTC
What is the function of this protein?
Pseudouridine synthase that catalyzes pseudouridylation of mRNAs and tRNAs (PubMed:28073919, PubMed:31477916, PubMed:32926445).  Mediates pseudouridylation of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harboring a stem-loop structure (PubMed:28073919, PubMed:31477916).  Constitutes the major pseudouridine synthase acting on mRNAs (PubMed:28073919).  Also catalyzes pseudouridylation of some tRNAs, including synthesis of pseudouridine(55) from uracil-55, in the psi GC loop of a subset of tRNAs (PubMed:32926445, PubMed:33023933).  Promotes the processing of pri-let-7 microRNAs (pri-miRNAs) independently of its RNA pseudouridylate synthase activity (PubMed:32926445).  Acts by binding to the stem-loop structure on pri-let-7, preventing LIN28-binding (LIN28A and/or LIN28B), thereby enhancing the interaction between pri-let-7 and the microprocessor DGCR8, which mediates miRNA maturation (PubMed:32926445).
What are the official names of this protein?
Pseudouridylate synthase TRUB1, TruB pseudouridine synthase homolog 1, tRNA pseudouridine 55 synthase TRUB1, Psi55 synthase TRUB1.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
Protein: MOAA_SULIM
Sequence: MIDRFGRPLEDLRITLTHVCNFECFFCHMEGEEGDNYILSKEDILLVAKVAKNFGINSVKLTGGEPTLRRDLVEIVRGLKQLGYRDVSMTTNGFLLKDLAYKLKLAGLDRINVSLHAISRETFKKITGVDAFDRVIEGIKSAIDVGLVPVKLNFVVNRRNREEVFKFIELSQNLGVNEIHLIELHPVGLGKLAFKEHDDLREIEEYIEKISIKKQIRKKHFRPRYVLPSGLIVEVVKPYANPIFCAGCNRIRLSVDGKLKTCLYREDNVIDILDILKGEYSEDVKEELLGRAFMIAIAIREPNFKYKI
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RS4_BACC4
Sequence: MARYTGPAWKLSRRLGISLSGTGKELEKRPYAPGPHGPNQRKKLSEYGLQLQEKQKLRHMYGMTERQFRRTFDQAGKMPGKHGENFMILLEARLDNLVYRMGLARTRRAARQLVNHGHIMVDGARVDIPSYRVKPGQTISVREKSNSLVVVKEAIEVNNFVPEYLTFDADKLEATYTRHAERSELPAEINEALIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: LIMYB_ARATH
Sequence: MRPKAVWEPEYHRVFVDLCVEQTMLGNKPGTHFSKEGWRNILISFQEQTGAMYDRMQLKNHWDTMSRQWKIWRRLVETSFMNWNPESNRFRATDDDWANYLQENPDAGQYRLSVPHDLKKLEILFAGCNVEVKNDEVSGVRKRRRSCYEEEDEDNQSMCSSSNPQTKGYWSPSTHKLFLDLLVQETLKGNRPDTHFNKEGWKTILGTINENTGLGYTRPQLKNHWDCTRKAWKIWCQLVGASSMKWDPESRSFGATEEEWRIYIRENPRAGQFRHKEVPHADQLAIIFNGVIEPGETYTPPSRSRKKLLHNRSESPQWRDTTPLSKMHVDEAETSRQNGCYAESQEDRIDSENAQPLDDMKLMNDVMLQESPVFVEIESAKPMYSIGECIKSLNAIEEVEQGSELYMFALDLFLKREYREIFLELKKPSLRIAWLQRLQSTSFPIPTTT
What is the function of this protein?
Transcriptional repressor that associates with ribosomal protein promoters.
What are the official names of this protein?
L10-interacting MYB domain-containing protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: P53_RABIT
Sequence: MEESQSDLSLEPPLSQETFSDLWKLLPENNLLTTSLNPPVDDLLSAEDVANWLNEDPEEGLRVPAAPAPEAPAPAAPALAAPAPATSWPLSSSVPSQKTYHGNYGFRLGFLHSGTAKSVTCTYSPCLNKLFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKKSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENFRKKGEPCPELPPGSSKRALPTTTTDSSPQTKKKPLDGEYFILKIRGRERFEMFRELNEALELKDAQAEKEPGGSRAHSSYLKAKKGQSTSRHKKPMFKREGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: RS5_LACPL
Sequence: MTFIDPSKLDLDDNVVAINRITKVVKGGRRLRFAALVIVGDHKGHVGFGTGKAQEVPEAIRKASEAAKKNLITVPMVGTTIPHEALGVYGGGRIMLKPAVEGSGVAAGGAVRAVMELAGVDDVTSKRLGSNTPVNVVRATFEGLKSLKTAEQVAALRGVSAEHLAE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: FOXJ1_HUMAN
Sequence: MAESWLRLSGAGPAEEAGPEGGLEEPDALDDSLTSLQWLQEFSILNAKAPALPPGGTDPHGYHQVPGSAAPGSPLAADPACLGQPHTPGKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSGAFKKRRLPPVHIHPAFARQAAQEPSAVPRAGPLTVNTEAQQLLREFEEATGEAGWGAGEGRLGHKRKQPLPKRVAKVPRPPSTLLPTPEEQGELEPLKGNFDWEAIFDAGTLGGELGALEALELSPPLSPASHVDVDLTIHGRHIDCPATWGPSVEQAADSLDFDETFLATSFLQHPWDESGSGCLPPEPLFEAGDATLASDLQDWASVGAFL
What is the function of this protein?
Transcription factor specifically required for the formation of motile cilia (PubMed:31630787).  Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157.  Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T).  Activates the transcription of a variety of ciliary proteins in the developing brain and lung.
What are the official names of this protein?
Forkhead box protein J1, Forkhead-related protein FKHL13, Hepatocyte nuclear factor 3 forkhead homolog 4, HFH-4.
What is the protein family that this protein belongs to?
Belongs to the FOXJ1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPG1_ASPFU
Sequence: MKALILVGGFGTRLRPLTLTLPKPLVEFGNRPMILHQVESLAAAGVTDIVLAVNYRPDVMVAALKKYEEQYNVRIEFSVESEPLGTAGPLKLAEKILGKDDSPFFVLNSDIICDYPFKQLAEFHKKHGDEGTIVVTKVDEPSKYGVVVHKPNHPSRIDRFVEKPVEFVGNRINAGIYILNPSVLKRIELRPTSIEQETFPAICSDGQLHSFDLEGFWMDVGQPKDFLTGTCLYLTSLAKRNSKLLAPNSEPYVYGGNVMVDPSAKIGKNCRIGPNVVIGPNVVVGDGVRLQRCVLLENSKVKDHAWIKSTIVGWNSSVGKWARLENVTVLGDDVTIADEVYVNGGSILPHKSIKQNIDVPAIIM
What is the function of this protein?
Involved in cell wall synthesis where it is required for glycosylation.  Involved in cell cycle progression through cell-size checkpoint (By similarity).
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosphorylase, GTP-mannose-1-phosphate guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_CHLAB
Sequence: MSKFYDVIKPKASRPPVWFLRQVGRYMPQYRELKGSQTLKDFFHNTEAITEATLLGPSLLKVDAAILFADILSLLDGFNISYDFAPGPQISFSPKEELIFTNDPQDTFSYLLKAIKNLVKRLSVPLIAFAASPFTMACYLLEGGASKDFPKTMAFLYQHPERFDALLKQLAEATVIYLKEQIQAGASAIQLFESSSLRLPSALFSRYVTRPNTQLITQLKNSVSSPISLFCRCFDENFIDLYSTGADTLHPDYHVNLSQIYTAVTHPGSLQGNIDPALFLLPQDQFLNHLEKYLSVLKHQPKYIFNSGHGILPETPLENVQAAVLCLTSISTS
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAKD2_RAT
Sequence: MDTSAIQQTLVKIYQRQAWQPPRKASKNETTVGKPRELAGGGSPADGGFRPSRVVVVAKTTRYEFEQQRYRYAELSEEDLKQLLALKGSSYSGLLERHHIHTKNVEHIIDSLRDEGIEVRLVKRREYDEETVRWADAVIAAGGDGTMLLAASKVLDRLKPVIGVNTDPERSEGHLCLPVRYTHSFPEALQKFSRGEFRWLWRQRIRLYLEGTGINPSPVDLHEQQLSLNQHSRAFNIERVDDERSEASGPQLLPVRALNEVFIGESLSSRASYYEISVDDGPWEKQKSSGLNLCTGTGSKAWSFNINRVAAQAVEDVLNIARRQGNLTLPLNKELVEKVTNEYNESLLYSPEEPKILFSIREPIANRVFSSSRQRCFSSKVCVRSRCWDACMVVDGGTSFEFNDGAIASMMINKEDELRTVILEQ
What is the function of this protein?
Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+).  Can use both ATP or inorganic polyphosphate as the phosphoryl donor (By similarity).
What are the official names of this protein?
NAD kinase 2, mitochondrial, Mitochondrial NAD kinase, NAD kinase domain-containing protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ZN597_HUMAN
Sequence: MASMPPTPEAQGPILFEDLAVYFSQEECVTLHPAQRSLSKDGTKESLEDAALMGEEGKPEINQQLSLESMELDELALEKYPIAAPLVPYPEKSSEDGVGNPEAKILSGTPTYKRRVISLLVTIENHTPLVELSEYLGTNTLSEILDSPWEGAKNVYKCPECDQNFSDHSYLVLHQKIHSGEKKHKCGDCGKIFNHRANLRTHRRIHTGEKPYKCAKCSASFRQHSHLSRHMNSHVKEKPYTCSICGRGFMWLPGLAQHQKSHSAENTYESTNCDKHFNEKPNLALPEETFVSGPQYQHTKCMKSFRQSLYPALSEKSHDEDSERCSDDGDNFFSFSKFKPLQCPDCDMTFPCFSELISHQNIHTEERPHKCKTCEESFALDSELACHQKSHMLAEPFKCTVCGKTFKSNLHLITHKRTHIKNTT
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 597.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAPA_DEHMC
Sequence: MKELGRLITAMVTPFKTDGTVDYAQAQKLALGLLDSGSDGLVVVGTTGESPTVTWEEEHALFAAVKSAVGNRGKVIAGTGANSTQEALENTLKAEKIGVDACLLVVPYYNKPTQEGLYLHFKTIAEATKLPCILYNVPSRTITHMNPETVIRLSQIPNIVGIKEASGKLDDIAQIINNVRPDFTVWSGNDSDTLPMLAMGSYGVISVASHLVGNQIKDMITSFVSGNTEHAAAIHRHLTPLIRSLFVVSNPIPIKYALNYLGFEVGGLRLPMTEADEKTAALIRESLRGYTIDLPIK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BACC_DROME
Sequence: MSAATEQQNNGDVAVEKVAADDVSAVKDDLKAKAAAEDKAAAADAAGDAADNGTSKDGEDAADAAAAAPAKESVKGTKRPAEAKSAESKKAKKAAAADGDSDEEEALEEIIEGDSEIESDEYDIPYDGEEDDIECDDDDDDNDDGSGSDDQA
What is the function of this protein?
Negatively regulates tyramine beta-hydroxylase tbh and thus the conversion of tyramine (TA) to octopamine (OA).  In tyrosine decarboxylase 2 (Tdc2) neurons, acts in an amine-mediated signaling pathway to negatively regulate acute ethanol sensitivity probably via tbh-mediated depletion of TA.
What are the official names of this protein?
Bacchus.
What are the subcellular locations of this protein?
Nucleus.
Protein: IFNG1_CARAU
Sequence: MIAQNMTIFFWGVCLLTSGWATYSEASVPENLDKSIDELKAYYIKDDHEIHNAHPVFLRVLKDLKVNLEEPEQNLLMSIIMDTYSRIFTRMENDSLDEATKERIAHVQEHLKKLRENYFPGKSAELKTYAETLWAIKEDDPVIQRKALFELKRVYREATLLKNLKNKERRRRQAKNTKNLKS
What is the function of this protein?
Cytokine which binds to interferon gamma receptor 1-like (ifngr1l) (PubMed:18831986, PubMed:19577303, PubMed:20507977).  Has activating effects on primary macrophages and neutrophils (PubMed:18831986, PubMed:20507977).  Induces nitric oxide production and phagocytic responses in macrophages (PubMed:18831986, PubMed:20507977).  Primes macrophages and neutrophils for production of reactive oxygen intermediates (ROI) (PubMed:18831986, PubMed:20507977).  Stimulates phosphorylation and nuclear localization of the JAK/STAT signal transducer stat1 (PubMed:20507977).  Promotes increased expression of a number of genes important for macrophage activity, including the interferon regulatory factors irf1, irf2, irf8 and irf9 (PubMed:18831986, PubMed:20507977).
What are the official names of this protein?
Interferon gamma 1, Interferon gamma, Interferon gamma 2.
What is the protein family that this protein belongs to?
Belongs to the type II (or gamma) interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1229_TRIEI
Sequence: MFTIDIIVKYTPVPFSIQRKSAEDAESTYEQIVESIRSGNPQILELTCEKIPEKKIAVVMSEVSGVQISQKSGAAATGRPPGFVTVAQ
What are the official names of this protein?
UPF0367 protein Tery_1229.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: CYSK_BUCAI
Sequence: MSKIYQDNSLTIGNTPLVRLNRIGNGNILVKIESRNPSFSVKCRIGANMIWHAEKNNNINKNVKLIEATSGNTGIALAYVAASRNYRLTLTMPETMSIERKKILKSLGAELILTDGRYGMKGAISKANDIISRNPSKYFLLKQFENPANPEIHQITTGPEIWNDTNGNLDILISAVGTGGTITGITRYIKKIKRKKNLISIAVEPSESPVITQFLAGKAIEPGPHKIQGIGPGFIPKNLDLTIIDQVITVSSEEAILTAKELMKKEGILAGISSGAALYAAIKIQQQKKFSDKKIVVILPSSGERYLSTELFSEL
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: Y1569_HAEIN
Sequence: MKDFADRYTFIRQGKMLVVKILPKEIFVLSFRRIKDKELKKLLEKDYALR
What are the official names of this protein?
Uncharacterized protein HI_1569.
Protein: CARA_ARCFU
Sequence: MKAALALEDGTYLEGKAFGAERGGLGEIVFCTSMTGYVEALTDPSYKGQILMMTYPLIGNYGVNREDFESDGVKVEGFVVKELCKNPSNWRSEMSVDELLKQYDVPGIEGVDTRMLTRKIRIYGSMKAAIGIGDVDREKLVRKAVEQPFISDIDLVDKVCVKEAKRFESDGDLEVVLVDCGVKMSIVRQLLKRGVNLTVVPYDFPAEKIKEMNPDGVFISNGPGDPARVKPTIETIRKLAGQIPMAGICLGHQLTALALGAKTFKLKFGHHGSNQPVKDFETGRVFISSQNHNFAVDTKTLPKEFEVTQINLNDHTVEGMVHKDFPLITVQYHPEAGPGPHDTYFFFDRYVDMLREYR
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.