PharMolix/UniProtQA huggingface dataset:
Protein: GLCA_ECOLI
Sequence: MVTWTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGAITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDIIRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLCLIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWKGVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKVWRPKNTETAISMGQSAGAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFAPGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISIFILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMFPFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMISPQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGIITLLQAYVFTGMLVS
What is the function of this protein?
Uptake of glycolate across the membrane (PubMed:11283302, PubMed:11785976).  Can also transport L-lactate and D-lactate (PubMed:11283302, PubMed:11785976).  Seems to be driven by a proton motive force (PubMed:11785976).
What are the official names of this protein?
Glycolate permease GlcA.
What is the protein family that this protein belongs to?
Belongs to the lactate permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_RHILO
Sequence: MANTSSAKKATRKIARRAAINKNRRSRVRTYVRQVEEALASGDKAAAQAAFKAAEPELMRAATKGVIHKNTASRKVSRLAARLKVLSA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: FABR_YERE8
Sequence: MGVRAQQKERTRRSLIEAAFSQLSAERSFASLSLREVSREAGIAPTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRSFTEAQAEAMVTIVFSAGAEVLDVDAEQRRQLEERLVLQLRMISKGAYYWYRREQEKLAVSRA
What is the function of this protein?
Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis.  By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer.
What are the official names of this protein?
HTH-type transcriptional repressor FabR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRT86_MOUSE
Sequence: MTCGSYCGGRAFSCASACGPRPGRCCISAAPYRGISCYRGLSGGFGSQSVCGAFRSGSCGRSFGYRSGGICGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKHEEKEQIKCLNSKFAAFIDKVRFLEQQNKLLETKWQFYQNRKCCESNMEPLFEGYIEALRREAECVEADSGRLAAELNHAQESMEGYKKRYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANAEALTQETDFLRRMYDEETRILHSHISDTSIVVKMDNSRDLNMDCVVAEIKAQYDDIASRSRAEAESWYRTKCEEIKATVIRHGETLRRTREEINELNRMIQRLTAEIENAKCQNTKLEAAVTQSEQQGEAALADARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDVEITTYRRLLEGEEQRLCEGVGSVNVCVSSSRGGVVCGDLCVSGTAPAVNTRVCSAPCSGNVVVGTPNACAPCAGAGACSGGCKKC
What are the official names of this protein?
Keratin, type II cuticular Hb6, Keratin-86, K86, Type II hair keratin Hb6, Type-II keratin Kb26.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: NRDR_STRM5
Sequence: MHCPFCQHADTRVIDSRVSEDGATIRRRRECEACGERFSTMETVELKLPAIVKSDGTREAFDQRKVRAGFDRALQKRAVAEDKIEAAVRAVVHQLRISGEREVPSIKVGEFVMNELRKLDHVGYVRFASVYRSFEDVADFREEIEKLERDLPSSTEQLQLLGDVIALTKKKKG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: QUEC_BORA1
Sequence: MHFPVFIMQNHQRRALVLFSGGQDSTTCLAWALDRYAHVETVAFDYGQRHRIELDARLNVLREIRGRFPAWAARLGQDHLLDLKVLGQVGDTAMTSDRAIEMQANGLPNTFVPGRNLLFLTLAAALGYRRQLDVLVGGMCETDFSGYPDCRDDTMKAQQVALSLGLGSRVTIETPLMWLDKADTWALADSLGGESLVQTIVEESHTCYVGERGQRHDWGYGCGECPACVLRKAGWSRWAERAPR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: APT_STRAW
Sequence: MTELVNITELLLSRIRDVRDYPEPGVVFKDITPLLADPAAFTALTGALAELTVRHGATKIVGLEARGFILGAPAAVQAGVGFIPVRKAGKLPGATLSQSYDLEYGSAEIEVHAEDLVAGDRVMVVDDVLATGGTAEASLQLIRRAGAEVAGVSVLMELGFLGGRARLEPALAGAPLEALLQI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_ACIBC
Sequence: MSAAPRIGILGAGGRMGRTLIQAVQQAGYQLAAAVERPESSLVGTDAGELAGIGSVGVKVSGSLADVLKDCDVIIDFTAPAATAQHLKLCREAGVAMVIGTTGMSDEQKAELDEAATHTPVVYAANYSVGVNVSIKLLELAAKVFGDTVDIEVIEAHHRHKVDAPSGTALMMGEAIADTLGRNLKEVAVYGREGHTGPRDRQTIGFETIRGGDIVGEHTVMFIGEGERVEVTHKATNRMNFAAGAVRAAAWVVGREARKYDMKDVLGLNDVQV
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5064_BACHK
Sequence: MGNEFRVCDDCQATNVKTLIPKLKKVDSCATIEVGCQSYCGPGRKKSFAFVNNRPVAAPTEDELIVKIEAKLNK
What are the official names of this protein?
UPF0741 protein BT9727_5064.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: VPX_HV2G1
Sequence: MTDPRERVPPGNSGEETIGEAFEWLDRTIEALNREAVNHLPRELIFQVWQRSWRYWHDDQGMSPSYTKYRYLCLMQKAVFIHFKRGCTCLGGGHGPGGWRSGPPPPPPPGLV
What is the function of this protein?
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells.  Targets specific host proteins for degradation by the 26S proteasome.  Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1.  This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1.  In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity).
What are the official names of this protein?
Protein Vpx, Viral protein X, X ORF protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus VPX protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG.
Protein: GALC_CANLF
Sequence: MTAAAGSAGHAAVPLLLCALLVPGGAYVLDDSDGLGREFDGVGAVSGGGATSRLLVNYPEPYRSQILDYLFKPNFGASLHILKVEIGGDGQTTDGTEPSHMHYALDENFFRGYEWWLMKEAKKRNPNIILMGLPWSFPGWIGKGFNWPYVNLQLTAYYIMTWIVGAKHYHDLDIDYIGIWNERSFDINYIKVLRRMLNYQGLDRVKIIASDNLWEPISASMLLDSELLKVIDVIGAHYPGTHTVKDAKLTKKKLWSSEDFSTLNSDVGAGCLGRILNQNYVNGYMTATIAWNLVASYYEQLPYGRCGLMTAQEPWSGHYVVESPIWVSAHTTQFTQPGWYYLKTVGHLEKGGSYVALTDGLGNLTIIVETMSHKQSACIRPFLPYFNVSRQFATFVLKGSFSEIPELQVWYTKLGKPSERYLFKQLDSLWLLDSSSTFTLELQEDEIFTLTTLTVGSKGSYPLPPKSEPFPQIYEDDFDVDYPFFSEAPNFADQTGVFEYFTNIEDPGEHRFTLRQVLNQRPITWAADAYNTISIIGDYKWSNLTVRCDVYIETPEKGGVFIAGRVNKGGILIRSARGIFFWIFANGTYRVTGDLAGWVIYALGRVDVTAKKWYTLTLIIKGRLSSGMLNGKTVWKNIPVSFPKNGWAAIGTHSFEFAQFDNFHVEATR
What is the function of this protein?
Hydrolyzes the galactose ester bonds of glycolipids such as galactosylceramide and galactosylsphingosine (PubMed:8661004).  Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon (By similarity).
What are the official names of this protein?
Galactocerebrosidase, GALCERase, Galactocerebroside beta-galactosidase, Galactosylceramidase, Galactosylceramide beta-galactosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 59 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: DMPP_PSEUF
Sequence: MSYNVTIEPTGEVIEVEDGQTILQAALRQGVWLPFACGHGTCATCKVQVVEGEVDIGEASPFALMDIERDERKVLACCAIPLSDLVIEADVDADPDFLGHPVEDYRGVVSALVDLSPTIKGLHIKLDRPMPFQAGQYVNLALPGIDGTRAFSLANPPSRNDEVELHVRLVEGGAATGFIHKQLKVGDAVELSGPYGQFFVRDSQAGDLIFIAGGSGLSSPQSMILDLLERGDTRRITLFQGARNRAELYNCELFEELAARHPNFSYVPALNQANDDPEWQGFKGFVHDAAKAHFDGRFGGQKAYLCGPPPMIDAAITTLMQGRLFERDIFMERFYTAADGAGESSRSALFKRI
What is the function of this protein?
Part of a multicomponent enzyme which catalyzes the degradation of phenol and some of its methylated derivatives (PubMed:2254259).  DmpP probably transfers electrons from NADH, via FAD and the iron-sulfur center, to the oxygenase component of the complex (PubMed:2254259).  Required for growth on phenol and for in vitro phenol hydroxylase activity (PubMed:2254258, PubMed:2254259).
What are the official names of this protein?
Phenol 2-monooxygenase, reductase component DmpP, Phenol 2-monooxygenase P5 component, Phenol hydroxylase P5 protein.
Protein: AROA_METAC
Sequence: MRVSISKSSVKGEVFAPSSKSYTHRAITLAALSNESIVRRPLLSADTLATIRASEMFGASVKREEENLIIHGFNGKPNVPDDVIDAANSGTTLRLMTAIAGLTDGITVLTGDSSLRTRPNGPLLKTLNQLGASACSTRGNEKAPLVVKGGLEGKKVSIEGSISSQFISALLIACPLAENSTTLSIIGKLKSRPYVDVTIEMLELAGVKIHTDENNGTKFIIPGKQKYDLKEYTIPGDFSSASYLLAAAAMTEGSEITVKNLFPSKQGDKLIIETLKQMGADITWDREAGIVTVRGGRKLKAVTFDAGATPDLVPTVAVLAAVAEGTSRIENAEHVRYKETDRLSALATELPKLGVKLKEEKDSLTITGGELKGAEVHGWDDHRIVMSLALAGMVAGNTTIDTTESVAISYPDFFEDMSNLGVKIKQISEE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_METM6
Sequence: MGAEKITSKIVEDANKNAEKILAEALNEKEAILTEAKEEASKKEQAIAKKGEKDAEMTKNRILAEARLSAKKKLLEEREKTIQLTLEKLEEDLVKLPQKDEYKDTLLKLIISGVYSVGGGELELLLNKKDFEVIDDSTLWALEKEMEDRLKKVTVLKKGEAKSIIGGCIIKTADHTKVSDNSLEATFERNLDSVRAKIAEMLF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: GCSH_STRGG
Sequence: MSNPQQLRYSKEHEWLSALEDGVATIGITEYAANALGDVVYAQLPEVGDTVTAGETCGELESTKSVSDLYSPVTGEVTAANQDVVDDPSLVNSAPFEGGWLFKVRVAEEPADLLSADEYTAFSGN
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: DAPE_BURMA
Sequence: MSATLALTEQLIARASVTPDDQHCQQLMIERLAALGFECETIASHGVTNFWAVKRGTAGRAGKLLAFAGHTDVVPTGPLEQWRSPPFVPTHRDGKLYGRGAADMKTSLAGFVVAAEEFVAAHPQHRGSIGFLITSDEEGPATDGTVKVVEALAARGERLDYCIVGEPTSTATLGDVVKNGRRGSMSGELVVKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDEGNEYFPPTTWQVSNLRAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDRHGLDYTLNWSVSGLPFLTPRGELSNALDAAIRAETGVSPELSTTGGTSDGRFIARICPQVIEFGPPNASIHKIDEHIDVRFVDPLKNVYRRVLEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: LSHR_CHICK
Sequence: MLPALLPLLLPALLPGAGGGRCPQRCACTQPALRCPTPPPGARPAPARASFTHLPVKVIPSHAFEGLRDAFIIEISQSDSLERIEASAFDSLPALSEILILNTKNLLHIEDGAFRNLPRLKYLSICNTGIIEFPDLTQIFSSEAHFILELCDNLRMTTIPQNAFQGMSNESLTLKLYKNGFEDIHSHAFNGTKLNQLILKDNKNLRRIHNDALRGATGPDVLDISSTALESLPSYGLEAIQVLNAMSSYSLKRLPPLDKFSSLLEAVLTYPSHCCAFQNLRTEKQNSLLSIFDNFSKQCESTMRKPASEVFYRDASSNTSLWPAEKHMYPLETGEEAFPYSYSTVFYEDEMTGFDFEYDFCQPKILTCTPEPDAFNPCEDILGYSFLRVLIWFINILALAGNFIVLLVLITSHYKLTVPRFLMCNLSFADFCMGLYLLLIASVDAQTSGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITIERWHTITYAMQLDRKLRLRHAVPIMLGGWVFSILIAVLPLLGVSSYMKVSICLPMDIETGLSQAYILLILMLNVIAFLVICACYIKIYVAVQNPELVAANKDTKIAKRMAILIFTDFTCMAPISFFAISAAIKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFFLLMSKLGCCKSRAELYRVNYFSAYTPNCKNGSSAPGPSKASQALLLLSASEKLCKTRRSTKKSQPECQ
What is the function of this protein?
Receptor for lutropin-choriogonadotropic hormone.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
What are the official names of this protein?
Lutropin-choriogonadotropic hormone receptor, LH/CG-R, Luteinizing hormone receptor, LSH-R, cLH-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURL_BACC4
Sequence: MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKRPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEKVAEVPADALAEEAPIYHKPSKEAAYFAEFQAMKMETPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEMGGKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMIHGKIFGQSPSIDLDVELKRQKQVLEAIQAGLVQSAHDVAEGGLAVAISESAIGAKGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTSTNEVTIHNEENEVLLTANVDEMRKAWKGAIPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH118_ARATH
Sequence: MEKLVHKEIEKRRRQEMASLYASLRSLLPLEFIQGKRSTSDQVKGAVNYIDYLQRNIKDINSKRDDLVLLSGRSFRSSNEQEWNEISNHVVIRPCLVGIEIVLSILQTPFSSVLQVLREHGLYVLGYICSSVNDRLIHTLQAEVNDLALIDLADLKDTLTLMK
What are the official names of this protein?
Transcription factor bHLH118, Basic helix-loop-helix protein 118, AtbHLH118, bHLH 118, Transcription factor EN 5, bHLH transcription factor bHLH118.
What are the subcellular locations of this protein?
Nucleus.
Protein: DBP7_ASPTN
Sequence: MADDGMLLNFTFSDDVVKKSEPKLKGGTWRDRLSAKKIAQHRAQPRKPSDGTAAPRPVKNPNRIQVSGTRPAKRQRTDDDHDAGLRDHDRAGQSQHQHQHPRQFISSLFSKNPLPRNAEEPTDEAPAEDAKPTNAPLIDGLDTFTNLGLSPTLAAHLLTKLELKAPTAIQKASISQLLKEESDAFIQAETGSGKTLAYLLPLVQRIMALSHPTNRTDATSTTDAEGQPVVHRDSGLFAIVLAPTRELCKQISVVLEGLLRCAHWIVAGTVIGGEKKKSEKARLRKGLNILVATPGRLADHLENTQALDVSNVRWLVLDEGDRLMELGFEQELQGIIKKLDARQRPSRIPGVPTKRTTILCSATLKMNVQKLGEMSLKDAIHIKADPADEDGDAKPKNDDESAFTVPAQLKQSYAIVAAKLRLVTLTAFLKRTFMRKGSVMKAIVFVSCADSVDFHFEVFTRKLQDSDENAEDSDASDTKEKPAAFTHNTIARATAFSNPSNPVTLHRLHGSLPQHVRTSTLASFARNKDASVLVCTDVASRGLDLPNVDLVIEYDPAFSAEDHLHRIGRTARLGRDGRALIFLQPGCEEGYVEILKRGYRDGGKALTRTNADDILKRGFGGNVESENKDWEEKATDWQMDLERWALEKPESLEMARRAYQSHIRAYATHVASERSMFNIKELHLGHLAKAFALRDRPSKINVPGLRQGKDDTKKDYKAARAPAAGKKRKTPGGRDDDDIPAAADTASAAQKMRAKMKEHMAGASEFNLA
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp7.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX31/DBP7 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UL95_EBVB9
Sequence: MFNAVKADMPDDPMLARRYGQCLELALEACQDTPEQFKLVETPLKSFLLVSNILPQDNRPWHEARSSGRVAEDDYDFSSLALELLPLNPRLPEEWQFGGQGWSSRMEPSQPEMGMGLCFEVFDGDLMRIALAWNKDEVIGQALQILAHSQTWTSLVPEDPLPWMWALFYGPRSHCEERHCVYAAARGKRGPILLPTAVYTPCANIEAFLAHLTRCVYALYLDVRDWKGEDIAPPFDVSRLNKMAKQLCLLPQEPFCITRVCLLCLLHKQNLNAQYKRPVDTYDPCLILTGEAERYMVDAVGNYREASTGTTVLYPTYDLGSIVADMVTYEDE
What is the function of this protein?
Part of the viral pre-initiation complex (vPIC) that is responsible for the expression of vPIC-dependent late genes (PubMed:31461506, PubMed:25165108).  vPIC is composed of at least BcRF1 that binds the viral TATT box, BDLF3. 5, BDLF4, BFRF2, BGLF3, BGLF4 and BVLF1 (PubMed:25165108).
What are the official names of this protein?
Late gene expression regulator BGLF3.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL95 family.
Protein: YHE8_SCHPO
Sequence: MIVQHKTAKIEEDHGLFQPILRPSDISKTTDTKFIQSSPYIEKEHWLDLGTLSVGHYFLSLALQTFVPKDSVRYAHLPYAQAFDIAEIVNLIREYSHKYHKHIPAFSAYIVAFRSVLQPEVQVSPEARHKLAEIDKGSHLEANVSGGLLKYWYGIPDDVFGQNLATCWWTSKESARLGGAGKIHREGLKAVRGWYKNWKIEEYELEVIEGGSSYIFKGLS
What are the official names of this protein?
UPF0643 protein PB2B2.08.
What is the protein family that this protein belongs to?
Belongs to the UPF0643 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RRF_THERP
Sequence: MIDEILRDAEQRMKKSIELLRQELAGIRAGRAAPSLLEHLEVNYYGTPTPLNQLATISAPEARLLVVQVWDRNAVSAVEKAIRQSELGLNPSVDGQTLRIQLPPLTEERRRQLVKLVHEEVEETKVAIRNIRRDALADIKELLKNKEISEDDERRAEQRLQDLTNRYIAEADKLGKQKEHDILEI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEA_DEIRA
Sequence: MPDSTADPSTADEVLARLHFDLPEDRIAQTGAEPRDTSRLMVVGEQIKHRMFRDLPDLLRPSDLLVFNESRVIPARVLARKPVVNGFGGGQVEVLLLREEFDVGANVWSAYLKPAKRAGHELWLGENEATGHRAEVVGVLDDGARLLRFDHDIKPHLDEIGRLPLPPYINAGDSDETWRERYQTVYAKTPGSVAAPTAGLHFTPELLARLDEMGVERASVTLHVGAGTFKPIQGPVADHVMHAERYEVSETNAAAITRAKAEGRRVVAVGTTTVRTLESAWDGAAVRAGAGETRIFITPGTRVEVPDLLITNLHLPGSTLLLLVAAFAGEDRIRAAYDAALSQDYRFYSLGDAMLLERLTSA
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_ECOSM
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWEQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNNDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHKVKPVLLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAAWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: 2AAAT_PSEPK
Sequence: MNQESISQSIAIVHPITLSHGRNAEVWDTDGKRYIDFVGGIGVLNLGHCNPAVVEAIQAQATRLTHYAFNAAPHGPYLALMEQLSQFVPVSYPLAGMLTNSGAEAAENALKVARGATGKRAIIAFDGGFHGRTLATLNLNGKVAPYKQRVGELPGPVYHLPYPSADTGVTCEQALKAMDRLFSVELAVEDVAAFIFEPVQGEGGFLALDPAFAQALRRFCDERGILIIIDEIQSGFGRTGQRFAFPRLGIEPDLLLLAKSIAGGMPLGAVVGRKELMAALPKGGLGGTYSGNPISCAAALASLAQMTDENLATWGERQEQAIVSRYERWKASGLSPYIGRLTGVGAMRGIEFANADGSPAPAQLAKVMEAARARGLLLMPSGKARHIIRLLAPLTIEAEVLEEGLDILEQCLAELN
What is the function of this protein?
Catalyzes the conversion of 2-aminoadipate (2AA) to 2-oxoadipate (2OA) (PubMed:31064836).  Is most active on L-2-aminoadipate (L-2AA) and shows only weak activity on the enantiomer, D-2-aminoadipate (D-2AA) (PubMed:31064836).  Shows moderate activity on 5-aminovalerate (5AVA) and weak activity toward 4-aminobutyrate (GABA) (PubMed:31064836).  Is involved in a D-lysine catabolic pathway (PubMed:31064836).
What are the official names of this protein?
2-aminoadipate transaminase, 2-aminoadipate aminotransferase, L-2AA aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: RL33_CALS4
Sequence: MRVKIALVCTECKNRNYHTTKNKKNDPDRLELKKYCKHCKKHTLHRETK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.