PharMolix/UniProtQA huggingface dataset:
Protein: NU5H_NYCOV
Sequence: MTKIVMLDYIPMLNNGGHRHPADIKPSMINSLLDSMSIILTSLCTFCEQLSLNEAIIVNLGINTLDQLLMSQAGRYLLLYYCIYALELYTVCYSTLSLILLYLIQLNYILLTNIVGYLQYSCSEIANLVYTYILLEGLLDVSELDALVVETLLDYLWVPCDLIIRYYRAYWYFEGVYFNLNIPYVQRSAYWLCVVIWNNIGWWTYQLMIIGWYSLSCLCIRLVPTILAIINLILTYIDLIIYLYDIYSNYSNMTWLGILYSTINSIIRYDISRIHAYQHLLTVIIPNYCLAIYNSGLILSSLLLDIYHYQIGLTILALQYLVAPLYISCSLLIYILCYIMTELLYSRSFYIDLLLRLLEIIYLDILVNSLISIIILILSVDVAYLIQLQVIILSQYINIISGYVAMPTTILITWYLYNIAVYIYYLVDYIATISTLIIWLLERILWVYGICANNIEPVVIDLPQLTLTSLDALLNQLLSEWCLLDAIMNVVTSVILLITVSCLGVLRIILFIAVYPVYCIGVLLLNTLLQVVVGLISYIIGTFMNAIILICDIYVYSIHRPFLPLIMYVYFVAAIILEPIIDIIHTIILAEHALFNTYCYIIFDILQPLHLQAFEFYRDLIWLIADLILAYIDLIRSTLVEGIISFIKWRLEQDFQLVYDICEFYLDEVKPRIIRYWNIYSRWVRFLIYCAGNNINLLVLLYVQFKGYTLPMIILFDLTRIQLYATIPVIISSYIYQGILQTMLIISYYNTLLVATLEFIQIWLTILSVSPEMLYTSTLGILLRSYYLLYEILLLEPTWVLFECLSTCVGLVELYLVTVETTVSNILIIDLILMEVLLEDIRQVATILTCILDWYILETCLDMQYADILLLMSSGLQSTVLNTIFDLLSLLGLLDETSIRFILELTVQVCTIPAALYSTIIYPYIVLVTRCLLYLPDVVQLYLTIGEYLLRETLYQLLIDWASCKLYSYNLYLLELYNIYYFWLSLLEKYWTFTYHIYNYTTLVELSPDLLISLISYIIDICILSLELLLEDIRWGSTIFVNLLDWYLLDTQLNIQYIDILLITSYSVQNTLLTVVFYILNLCGILNEISIQILFEITVQICTILATIYCTVVLPYILIILEILSYLPEIVQLYLDIGEHLLLEILWQLLIDLLYYRAYDYILIAQLLCKVTYLLYIVLEQLLLVIIDLYIYIIGDLLIIGSCHVGNHIIDILCSAENVYFLYFMIFIGYLLCGIFAFFYHGYLGTRGIFYLSEMIIMGILIFSIVTLYYNLKYHLALDIILGELALSNEVIFTNIITFDILSILGVLLVATLTAIILTFGVEYMLREAFAYNVLATLVLFSASIICFIVSYSFGLMIIFWEISGTLSLFLIDMYYARIRTTQAVTRTFALNRFGDLWMFTASIEIYSLCHNDALPTLFALLPYAQFNLSILGNLIFDFTIPTVIVFSIFSAAACKCAQFLLFVWLPDAMEAPTPASALIHSSTLVVMGIFMILRFAPILHLSVYTLYIMSILGSLTVAYGAILATQTSDLKKAVAYSTISQIGYLFTGCAFLAFRATLIYLILHAICKALLFVLVGYIVHMFGGTTSLRRMGGIYYIVPDIAIYMFILCMVLAGAPYTVGFFAKELIVTTLTNTSSPVATFIICCWIISFACTPFYLYRICVLPLFGRPRCSRRVFRNIVSPQSTYNFIDSDSSLNSLLHKFTNLITRWSVQGRFTNLLHLLLLLIVLFCGEFLVFLVTGLFGTSTTLFSDTAIDDSVYQLTDYYLLSYYRVRNIQLLIIVLFALVTLYITAINNQLTFNIIYLSVVLPILAIIFICLGHYFLVDFTVYIYNISNSLIFELLCDLAIC
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Hydrogenosome membrane; Multi-pass membrane protein.
Protein: NU2C_PROMM
Sequence: MPDMGVFLLATQAVAPPGELLNLALNAGAIAPEGAVLVAMLATLLVDLAGEQAAARWVPPICYAGLGTALVLLAQQWNAPLEPSFLGAFLADNLAISFRAVVALSTLLSLLISWRYAEQSGTPIGEYAAILLAATLGAMLLCGSTDLVSVFVSLETLSVASYLLAGYMKRDARSSEAALKYLLVGSAAAAVFLYGASLLYGLSGTTSLQAIGLALLTSPTPLAALSLVFVLATVAFKIAAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALALRLLVGCFGAFDNQWKLLFTVLAVLSMTLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLVCGTEDGFAAMVLYMAAYLFMNLGAFACIILFSIRTGSDRISDYAGLYQKDPLITLGLSLCLLSLGGIPPMLGFFGKIYLFFAGWADHQYLLVVVGLVTSVVSIYYYISVIKMMVVKEPKEASDVVKSYPSIKWSTIGMPPLRIALVGCVVVTAVGGILSNPLFQWANNAVAGTPLLQEAIALGSQRSIG
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: TPMT_PSEA7
Sequence: MQADFWHARWANNQIGFHLDEVNPYLMRHLSRLRLQAGEQVLVPLCGKTLDLAWLAAQGLDVLGVELSEKAVSDFFAENGLQPAIDQMDGFRRYRAAGITLLQGDFFALQSGHLAGCRAFYDRAALIALPPDMRERYAGHLQAILPARSLGLLVTIDYPQGEMAGPPFAVPDAEVREHYAAGWRIEELERGDVLGVNWKFLERGVSWLNEAVYLLQRG
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARMC9_BOVIN
Sequence: MVDVLAHESELLGLVKEYLDFAEFEDTLKTFLKECKIKGKPLSKSTCGSLRDPKSLKFQRDLLAAFDSGDQKVFFRLWEEHIPRPIRDGDSLAQKLEFYLHIHFAIYLLKHSAGRPDKEDLDERISYFKTFLETKGAALSQTTEFLPFYALPFVPNPMAHPSFKELFQDSWTSELKLKLEKFLALMFKASNTPKLLTLYKENGQSNKDVLQQLHQQLVEAERRSMTYLKRYNRIQADYHNLIGVTAELVDSLEATVSGKMITPEYLQSVCVRLFSNQMRQSLAHSVDFTRPGTASTMLRASLAPVKLKDVPLLPSLDYEKLKKDLILGSDRLKAFLLQALRWRLTTSHPGEQRETVLQAYISNDLLDCHSHSQRSVLQLLQSKSEVVRQYTARLINAFASLAEGRRYLAQSTKVLRMLEERLKEEDKDVITRENVLGALQKFSLRRPLQTAMIQDGLIFWLIDILKEPDCLSDYTLEYSVALLMNLCLRSAGKNMCAKVAGLVLKVLSDLLGHENHEIQPYVNGALYSILSIPSIREEARAMGMEDILRCFIKEGNAEMIRQIEFIIKQLNAEELLDGVLESDDDEDEDDEEDHDTMEADLDKDELIQPQLGELSGEKLLTTEYLGIMTNTGKARRRGTAGVQWGGPEPLRRPVTPGGHRTGYPA
What is the function of this protein?
Involved in ciliogenesis.  It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (By similarity).  Acts as a positive regulator of hedgehog (Hh)signaling (By similarity).  May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (By similarity).
What are the official names of this protein?
LisH domain-containing protein ARMC9.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized to the proximal region in cilia. Stimulation of Hh signaling leads to redistribution of ARMC9 toward the ciliary tip within 6 hours, follow by a gradual return to its original proximal location (By similarity). Localizes to the daughter centriole of the primary cilium in RPE1 cells (By similarity).
Protein: SYE_LACDA
Sequence: MANKKIRVRYAPSPTGHLHIGNARTALFNYLFARHNKGTLVLRIEDTDTARNVEGGAESQIENLHWLGIDWDEGPDIGGDYGPYKQSERKDIYQKYIDQLLEEGKAYYSFKTEEELEAQREEQRAMGIAPHYVYEYEGMTTDEIKQAQDEARAKGLKPVVRIHIPEGVTYEWDDIVKGHLSFESDTIGGDFVIQKRDGMPTYNFAVVIDDHLMEISHVLRGDDHISNTPKQLCVYEALGWEAPVFGHMTLIINSATGKKLSKRDESVLQFIEQYRELGFLPEAMFNFITLLGWSPVGESEIFSKREFIKQFDPARLSKSPAAFDQKKLDWVNNQYMKTADRDELLDLALHNLQEAGLVEANPAPGKMEWVRQLVNMYANQMSYTKQIVDLSKIFFTEAKYLTDEEVEEIKKDEARPAIEEFKKQLDKLDNFTAKKIMGAIMATRRETGIKGRKLFMPIRIATTRSMVGPGIGEAMELMGKDTVMKHLDLTLKQLSEAGIE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_ACIC1
Sequence: MKSAVETLSPTRVKFTVEVGFDELQPTVAAAYRKVAEQVRVPGFRPGKVPPPIIDRRIGRGVVLEQALNDAIPQFYGQAVDEAAVAVISQPEIEVTNFADGEGLTFTAEVDVRPTIELPDPESITVTVDPVTVSDADVDAELAALADRFATLKPVDRPARRGDFVTIDMTVRLDGEVLEDGTVTGASYEVGSAQLVEGLDEALEGLTAGQSAEFDAPLAGPYAGRTARAEVTVRAVREKQVPALDDAFAQQASEFDTLEELRAHIRERIGRTRRIQQHVQARERLLQTLLDSLDIPVPERIVDAEVRSRAEQLRRYAEARGMDAEGLLAQQGESLHDHEAHVRADVERELRVQFLLDTVVAREQLQLQEAELTDYLIQRATRLGVSPDDYANQLVRTNTVPLAVADALRGKALTYLLQRVRVVDTTGAPVNLEGGSTPAAEAEPAVSEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ACP_LISIN
Sequence: MAEVLEKVTKIIVDRLGVEESKVTLEASFKEDLGADSLDVVELVMELEDEFGVEISDGDAENINTVGDAVKYIEANA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_PELTS
Sequence: MSVLAETIKEGAREMGIVITEKQVRQFEEYYSLIIERNKSLNLTAITGEREVAVKHFLDSLTCLKAVPLEDGTSLMDVGTGAGFPGIPLKICRPSVRVKLVESAEKKAVFLREAIGRLGLEMAEAIWARAEDVGKDPDHREKYGCVVARAVAELAVLAEYCLPAAGVGGCFLAMKGPKAEEEAVRAKDAIKILGGRLEEIINLKLPFTGDRRSLVVIRKIGETPEKYPRRPGVPQKRPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APEB_PSE14
Sequence: MRAELNNGLIDFLKASPTPFHATATLVQHFEAAGFQRLDERDTWAIETGGRYFVTRNDSSIVAFRMGRQSPLTGGIRMVGAHTDSPCLRVKPQPELQRQGFWQLGVEVYGGALLAPWFDRDLSLAGRVTFRRDGKVESQLIDFKLPIAVIPNLAIHLNRTANEGWAINAQNELPPILAQVAGDERADFRALLTDQLAREHGLNADVVLDYELSFYDTQSAAVVGLNGDFLAGARLDNLLSCYAGMQALLNSESDETALLVCTDHEEVGSSSTCGADGAMLEQIVQRLLPSSEDYVRTIQKSLLISADNAHGIHPNYAEKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEEVPVQSFVVRSDMACGSTIGPITASHLGIRTVDIGLPTFAMHSIRELAGSHDLAHLVKVLSAFYASHELP
What are the official names of this protein?
Probable M18 family aminopeptidase 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M18 family.
Protein: THIC_PROM4
Sequence: MRASWVANRQGKSNVSQLHFARQGMITEEMAYVANRENLPESLVMEEVARGRMIIPANINHLNLEPMAIGIASKCKVNANIGASPNASDVGEELKKLELAVKYGADTVMDLSTGGVNLDEVRTAIINASPVPIGTVPVYQALESVHGSIEKLSEEDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHKQNPLFSRFDDICEIFKRYDCSFSLGDSLRPGCLHDASDEAQLAELKTLGQLTKRAWAHDIQVMVEGPGHVPMDQIEFNVRKQMEDCSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADIARHRSGARDRDDELSKARYAFDWNKQFELSLDPERARQYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDKDLDDLEDVIKSKDASKINL
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ACCD_AGRFC
Sequence: MNWITNYVRPRINSMLGRRPEVPENLWIKCPETGEMVFHKDLEDNKWVIPASGYHMKMPAKARLADLFDGGIYEALAQPKVAQDPLKFRDSKKYTDRLRDSRAKTEQEDTILAGVGLLKGLKIVAVVHEFQFMAGSLGIAAGEAIVKAFERAISERCPLVMFPASGGARMQEGILSLMQLPRTTVAVNMLKEAGMPYIVVLTNPTTGGVTASYAMLGDVHIAEPGAEICFAGKRVIEQTIREKLPEGFQTSEYLLEHGMVDMVIDRREIPDTLASMLKIMTKAPADNANAVVPLAASA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAPZ_ECOSE
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: RL16_WOLPP
Sequence: MFVPKKSKYKKVFKGRIKGNAKGGSTLSFGDYGLKAMEVGKVQSKHIETARRVISRTLKRSGKVWIRIFPDTPVSKKPADVRMGKGKGSIEFWVFKAKPGRVLFEISSDVPMHLARLALEKATAKLPMKCKFISNHN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SYS_HELPS
Sequence: MIDKKLLLQDFEMVALSLKKRNNAMDDALERLREVITHYKKQLIELEGLQAFQNKVSKEFGIKMAQKVDTSDLKKELENNKIKLNELSKSVGELEQQIDLRLSIIPNLVDEKTPLGASEEDNIEIKKILTPRNFTFKPKEHFELAQQNGWIDFESGVKLAKSRFSVIRGFGAKIYRALIHLMLDFNEKNGFEIIYTPALVNEKMLFGTGQLPKFKEDVFKIENENLYLIPTAEVTLTNLYNDTIVSVEKLPIKMTAHTPCFRSEAGSAGKDTRGMIRQHQFDKVELVAITHPKESDAMQEHMLESASEILKALELPHRFVQLCSADLGFSASNTIDIEVWLPGQNCYREISSVSNTRDFQARRAKIRFKENQKNQLAHTLNGSSLAVGRTMVALMENHQQADGSIHIPKALEKYL
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IORA_PYRHO
Sequence: MVKVTDIVLWDKPGEKVLLLGNQAIVRGALEGNIGVYAAYPGTPSSEITDTMAMVAKKAGVYMEYSTNEKVAFETALSASWAGLRAMTAMKHVGLNVAMDSFMTVSYMGINGGLIVVVADDPSMWSSQNEQDTRAIAKFANIPVLEPSSVQEAKDMVKYAFEISEKYGQMVILRTTTRSSHMRGDVVLGELPQEIKEGKRKFGNFKKNPEKYVDIPAFQRPKHPWLLETIEKFREEFNTSPFNWIEGPEDAKVGIIAPGLSYAYVKEALAWLGIDNVKILKLGTPFPVPYGLLEKFFNGLERVLIVEELEPVVEEQVKVWAFDNNINIEIHGKDLVPRVYEMTTRRAVEAVAKFLGVETPINFQEIDEKYKKVQEMVPPRPPSLCPACPHRNTFFAIRKAATPRAIFPSDIGCYTLGVLPPLKTVDTTIAMGGSIGVAHGLSIALNGALGEEQRKTGKEKKIIVATIGDSTFFHTGLPALANAIYNRSNVLIVVMDNMVTAMTGDQPNPGTGETPHGPGKRILIEEVARAMGADFVAVVDPYDIKETYETIKKALEVEGVSVVVSRRACALYRIGQLRREGKQWPIYQVNEEKCTGCKICINAYGCPAIYWDAEKKKARVDPLMCWGCGGCAQVCPFGAFEKVREGEL
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
What are the official names of this protein?
Indolepyruvate oxidoreductase subunit IorA, IOR, Indolepyruvate ferredoxin oxidoreductase subunit alpha.
Protein: PYRC_RHILW
Sequence: MQSITIRRPDDWHLHLRDGAMLEGVIADTSRTFARAIIMPNLVPPVVTTSDATAYRERILKALPAGHRFQPLMTLYLTEHTSPDDVEAGARSGLITAVKLYPAGATTNSHGGVRDMEKAMPVLERMAAIGLPLCVHGEVTTPEVDIFDREAVFIDTVLDPLRRRLPELKVTMEHVTTSDGIDYIKAAKANLAGSITSHHLIINRNAILVGGIRPHYYCLPVAKRENHRLALRAAAVSGDARFFLGTDSAPHVDPLKECACGCAGIYTSINTMSCLAHVFEEEDALDRLEAFTSLNGPAWYGLQPNEERITLSRQAEPVVFPAKIETGAGSVTVFDPMYPLHWHVVA
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: FL2D_HUMAN
Sequence: MTNEEPLPKKVRLSETDFKVMARDELILRWKQYEAYVQALEGKYTDLNSNDVTGLRESEEKLKQQQQESARRENILVMRLATKEQEMQECTTQIQYLKQVQQPSVAQLRSTMVDPAINLFFLKMKGELEQTKDKLEQAQNELSAWKFTPDSQTGKKLMAKCRMLIQENQELGRQLSQGRIAQLEAELALQKKYSEELKSSQDELNDFIIQLDEEVEGMQSTILVLQQQLKETRQQLAQYQQQQSQASAPSTSRTTASEPVEQSEATSKDCSRLTNGPSNGSSSRQRTSGSGFHREGNTTEDDFPSSPGNGNKSSNSSEERTGRGGSGYVNQLSAGYESVDSPTGSENSLTHQSNDTDSSHDPQEEKAVSGKGNRTVGSRHVQNGLDSSVNVQGSVL
What is the function of this protein?
Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29507755).  Required for accumulation of METTL3 and METTL14 to nuclear speckle (PubMed:24316715, PubMed:24407421, PubMed:24981863).  Acts as a mRNA splicing regulator (PubMed:12444081).  Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability (PubMed:17088532).  Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes (PubMed:17095724).
What are the official names of this protein?
Pre-mRNA-splicing regulator WTAP, Female-lethal(2)D homolog, hFL(2)D, WT1-associated protein, Wilms tumor 1-associating protein.
What is the protein family that this protein belongs to?
Belongs to the fl(2)d family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, nucleoplasm. Cytoplasm. Note=Mainly nuclear with some fraction located in the cytoplasm. ZC3H13 is required to anchor component of the MACOM subcomplex, such as VIRMA, in the nucleus.
Protein: LYS_CLOAB
Sequence: MKGIDIYSGQGSVDFNAVKESGVEVVYIKATEGLTYTDSTYKDFYDGAKNAGLKIGFYHYLRANDPTSEAEHFFNTISGLSLDCKCAIDVEVTLGQSIDQISSNVRKFADYLINKGLDVCVYTYTNFYKDNLNSTVKDLPLWIAEYGVSKPNIDASYVGFQYSDSGSVNGISGSADLDEFSEGILVGGTVVIDPGQGGDDNIKAIQQDLNILLKRGLEVDGIEGPETEAAIKDFQSIMGLTVDGIWGTNTSGAAQQIFSRPLDGVAYPHYEYATRYIQYRVGASVDGTFGSGTKAKVAAWQSNQGLMADGVVGSATWSKLLDEN
What are the official names of this protein?
Autolytic lysozyme, 1,4-beta-N-acetylmuramidase, Autolysin.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 25 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm.
Protein: MUTH_SALTI
Sequence: MSALCPLLTPPASEALLLAQARQLSGYTLGELAVMAGITTPKDLKRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTGNSGVTWETSHVRHKLKRVLWVPVEGDRSIPLAERRVGSPLLWSPSEEEDRQLRLDWEELMDMIVLGQVERITARHGEVLQLRPKAANARALTEAIGARGEPILTLPRGFYLKKNFTQALLARHFLLQNP
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2407_METC4
Sequence: MTQSPFTLEANGLVLAVRLTPRASRTGLDGVRTEASGRPVLSLRVAAPPVEGAANAALTAFVAKSLGLRKAEVTLLSGETSRTKRLHLSGDPQMLAARVEAWLGG
What are the official names of this protein?
UPF0235 protein Mchl_2407.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: PHNN_PECPW
Sequence: MTKLIYLIGPSGAGKDSLLRAIRQLSLPHLLVAHRYITRPAEIQGENHIALTPEEFAIRQQLGIFALNWQAHQCHYGIGIEIDYWLQRGSDVIVNGSRAYLTQARERYGNTLFPICLTVSESALRQRLRARGRESEQQIAMRLQRAEEEQNRLQSDCVLLNNDGDLQHTLSTFQSLLPLDRACTAHRE
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: UPPP_ACISJ
Sequence: MDTLLLLKAAIMGVVEGLTEFLPISSTGHLILAGSLLGFDDAKAKVFDIAIQTGAIFAVILVYWQRIRATLVALPTERQARRFALNVLIGFLPAVLLGLLLGKAIKAHLFTPVVVASTFILGGFVILWAERRQQAAVRIHAVDDMTPLDALKVGLVQCLAMVPGTSRSGATIIGGMLLGLSRKAATDYSFFLAIPTLIGAGVYSLYKERALLSAADIPLFAVGLVFSFISAWLCVRWLLRYISLHSFVPFAWYRIAFGLVVLATAWSGLVTWAE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS27A_MAIZE
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGAKKRKKKTYTKPKKIKHKHKKVKLAVLQFYKVDDATGKVTRLRKECPNTECGAGVFMANHFDRHYCGKCGLTYVYNQKA
What is the function of this protein?
Ribosomal protein S27a is a component of the 40S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: IF3_MICAN
Sequence: MIDKRRTTRDLPQINERIRFPEIRVIDSDGSQLGIITPAEALRVAEEKELDLVLVSETASPPVCRIMDYGKYKFEQEKKAREAKKKQHTADIKEVKMRYKIDEHDYNVRVNQAQRFLKAGDKVKATITFRGREIQHSNLAEELLARMAKDLQDVAEVQQAPKKEGRNMMMMLSPKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_RHIE6
Sequence: MVKVIASSVRKGNVLDVDGKLYVVLTAQNFHPGKGTPVTQVDMRRIVDGVKVSERWRTTEQVERAFVEDVNFQYLYEDGEGFHFMNPANYDQVVVSQETMGDQKAYLQEGMTCILSIHEGIPLALELPRHVTLEIVETEPVVKGQTASSSYKPAMLSNGIRTSVPPHIDAGTRVVIATEDNSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_ACTP2
Sequence: MKTTIRKISARKSIALVAHDSCKQSLIQWTLQHKASLTPHTLYATGTTGHLLARESGLNIQALLSGPMGGDQQLGGLIAEKKIDILIFFWDPMNAAPHDPDVKALMRIATVWNIPVAINETSANFLLSAALFDQEIGINVPDYDGYLAERLA
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: TLP_ALKCK
Sequence: MAKRDDRSNNPERIENIIGNTLQNMDEARDYAKAHSEELSEEEKQEIEQKNERREQSIDGLREELKDEVNDQKNNS
What are the official names of this protein?
Small, acid-soluble spore protein Tlp.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
What are the subcellular locations of this protein?
Spore core.
Protein: RK20_STIHE
Sequence: MTRVKRGIVARKRRKKILNYTKGFRGAASKLFRTANQRYMKALKLSFVNRRKKKRDFRSLWISRLNAAVRKNGLNYNEFIFALKICNINLNRKTLSQISICDPQTFNLLYDTLKPLLIKHLNTK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.