PharMolix/UniProtQA huggingface dataset:
Protein: PSBL_MAIZE
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TRAM1_HUMAN
Sequence: MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLPATEEQATESVSLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKKEDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICVTQAFMMWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTSNVADSPRNKKEKSS
What is the function of this protein?
(Microbial infection) In case of cytomegalovirus infection, participates in US2- and US11-mediated ER-to-cytosol retrotranslocation and subsequent degradation of major histocompatibility complex (MHC) class I heavy chains, thereby decreasing the immune detection by cytotoxic T-cells.
What are the official names of this protein?
Translocating chain-associated membrane protein 1, Protein TRAM1.
What is the protein family that this protein belongs to?
Belongs to the TRAM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: YIDD_DESHY
Sequence: MMKRLLIGMIRIYQRYISPLKRPSCRFYPTCSEYSIQAIQKYGVVKGCWKSLVRILKCHPFHPGGYDPV
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VL2_HPV14
Sequence: MARARRVKRDSATNIYRTCKQAGTCPPDVINKVESTTIADKILQYGSAGVFFGGLGISTGKGTGGTTGYVPLGEGPAVRVGGAPTIIRPALVPDTIGPSDIIPVDTLDPVEPTTSSIVPLTDSTGPDLLPGEVETIAEVHPGPSRPPTDTPVTTSTGGSSAILEVAPEPTPPSRVRVTRTQYHNPSFQVITESTPTTGESSLADNILVTSGSGGQTIGGATPELIELQELPSRYSFEIEEPTPPRRTSTPLQRIQTAIRRRGGLTNRRLVQQVSVENPLFLTRPSRLVQFQFDNPAFEEEVTQIFEQDIEDFNEPPDRDFLDVQRLGRPQYSETPAGYLRVSRLGQRRTIRTRSGAQIGSQVHFYRDLSSINTEDPIELQLLGQHSGDATIVQGPVESTFVDINVDENPLSEDFSAHSDDLLLDEANEDFSGSQLVVGNRRSTSSYTVPRFETTRSGSYYAQDTKGYYVAYPEDRDISMDIIYPTPELPVVIIHTYDTSGDFYLHPSLHKRLKRKRKYL
What is the function of this protein?
Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers.  Plays a role in capsid stabilization through interaction with the major capsid protein L1.  Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network.  Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network.  Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.  Mediates the viral genome import into the nucleus through binding to host importins.  Once within the nucleus, L2 localizes viral genomes to host PML bodies in order to activate early gene expression for establishment of infection.  Later on, promotes late gene expression by interacting with the viral E2 protein and by inhibiting its transcriptional activation functions.  During virion assembly, encapsidates the genome by direct interaction with the viral DNA.
What are the official names of this protein?
Minor capsid protein L2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host early endosome. Host Golgi apparatus.
Protein: APT_NEIMA
Sequence: MLVHPEAMSVGALADKIRKIENWPQKGILFHDITPVLQSAEYFRLLVDLLVYRYMDQKIDIVAGLDARGFIIGAALAYQLNVGFVPIRKKGKLPFETVSQSYALEYGEAAVEIHTDAVKLGSRVLLVDDLVATGGTMLAGLELIRKLGGEIVEAAAILEFTDLQGGKNIRASGAPLFTLLQNEGCMKG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y462_XANOM
Sequence: MHIHDWPTNERPREKLLARGATALSDAELLAIFVGSGLRGQDAVQTARDLLHRHGPLRPLLDRPAKALERLPGLGPASACKLAAALELAHRHLMSALERGEALSDPPSVGRYFSQRLRARAYEVFAVLFLDNRHRAIAFEELFTGTIDGADIHPREVVRRALLHNAAAVIVGHNHPSGNPEPSEADRAVTKRLLDSLELVDIRLLDHFVIGDGRPVSLAERGWLE
What are the official names of this protein?
UPF0758 protein XOO0462.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: PLYA_ASPFN
Sequence: MANFKLFLALAACLSGQALAAPTKTIGKRAAITDVAHGYASQNGGTTGGAGGTTTTVSSYAQFTEAVSSDDAKIVIVDGTITETADQVKVGSNTSIIGKDANAILEGFGLLVKEKENVIIRNLGVKKVLADNGDAIGVQYSNNVWIDHCDVSSDRDHDKDYYDGLIDLTHAADYVTVSNTFVHDHWKAMLFGHSDSNGDEDTGHLRITVNNNYLNNLNSRGPSFRFGTGHLYNNYYLDVSDGINTRQGAQLLVEGNVWSGGKKPLYSTDDGYAVARDNDFGDGENTAPEGTLTSVPYEYDLLAASAVKDAVVGTAGQTLTF
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SLU7_YARLI
Sequence: MSKPATTLDGLQDGSVELQKRLSAKRDAEGELKHEEDRKLRKEGKTQTPVTNQEGDVLNPYIPRFMSSAPWYAKAGDDDPSASSLDHLKKDKTDSKKEEWYARGQDRSSLERPKKFRKGACENCGAMTHKKKDCMERPRKVGAKYKADNLQADDVISNPHMSWDSKRDRWNGYDAEDFKRVIDEHNMTEELQKKLHGDAPAETDAEKAAAVEEAIRKSTRTLRLREDTAVYLKDLNSETVYNPGSRTFRTADEGYIDKDGMFVRHTTGEGKEMEELTRIAEAESALGNQIHLHANPTAAAIAAKRIKEEAEKAKDAEKRALEEKYGKQDHVRVRPKEYTSVVTAKKPTVIRAKNAQGIAVSKYEEDVFPGNHTSVWGSYYDKETAKWGYACCHCLIKNGYCVGEKGKKKKGAMDTV
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VME1_CVMA5
Sequence: MSSTTQAPEPVYQWTADEAVQFLKEWNFSLGIILLFITIILQFGYTSRSMFIYVVKMIILWLMWPLTIVLCIFNCVYALNNVYLGFSIVFTIVSIVIWIMYFVNSIRLFIRTGSWWSFNPETNNLMCIDMKGTVYVRPIIEDYHTLTATIIRGHLYMQGVKLGTGFSLSDLPAYVTVAKVSHLCTYKRAFLDKVDGVSGFAVYVKSKVGNYRLPSNKPSGADTALLRI
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: BPPAD_BOTFO
Sequence: QNWPHPPMPP
What is the function of this protein?
This peptide evokes slight hypotension (-2 mmHg), when injected alone into rats.  It has a no bradykinin-potentiating effect, when 60 nmol of BPP-10d are coinjected with 0. 5 ug of bradykinin into rats.  It inhibits angiotensin converting enzyme (ACE) activity with a K(i)app of 9. 12 uM.
What are the official names of this protein?
Bradykinin-potentiating peptide 10d, BPP-10d.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: CLCB_SHIB3
Sequence: MFRRLLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWIACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYNVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGGVIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTEMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQHS
What is the function of this protein?
Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
Voltage-gated ClC-type chloride channel ClcB.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS6_NATPD
Sequence: MALTKRIIPCIDVDLNEDGEAAVYTGVNFEDLEYTGDPVELAKKYNEAGADEFVFLDITASAEGRETMLDTVSAVADECFIPLTVGGGIRTRDDIKETLRAGADKVSINTGALQRPELIGEGAEAFGSQCIVISVDARRRFDEAGEHYVEVDGESCWFECTIKGGREGTGTDVVEWAGEAADRGAGELFVNSIDADGTKDGYDIPLTKAVCDNVPTPVIASSGCGSPEHMAEVFEDADADAALAASIFHFEEYSIEETKRSLDEQGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1213_BACC4
Sequence: MAKDSSFDIVSKVELPEVTNAINIALKEIQNRYDFKGSKSDIKLEKEVLVLTSDDEFKLEQVKDVLISKLVKRNVPIKNLDYGKVEAATGNTVRQRATLQQGIDKDNAKKINNIIKEMKLKVKTQVQDDQVRVTAKSRDDLQAVIAAVRSADLPIDVQFINYR
What are the official names of this protein?
UPF0234 protein BCB4264_A1213.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: DGOD_XANCB
Sequence: MKITRLTTYHAAPRWLFLKVETDEGITGWGEPVIEGRARSVEAAVHELAGYVVGKDPARINDLWQTMYRAGFYRGGAILMSAIAGIDQALWDIKGKALGVPVYELLGGLVRDRMKTYRWVGGDRPGAIIAQINDYRALGFDTFKFNGTEEMKLIDSARAVDAAVVKVAEIRETFGNSIDFGIDFHGRVGAPMAKALLRELEPFKPLFVEEPVLAEQAEYYPRLAASTCIPLAAGERMFSRFEFKNVLCAGGIGMVQPDLSHAGGITECVKIAAMAEAYDVGFAPHCPLGPIALAACLHVDFVSHNAVLQEQSIGIHYNEGADLLDYVINKEDFHCVDGSIAALPKPGLGVEINEDMLKRANENPPDWRNPVWRHADGSIAEW
What is the function of this protein?
Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate.
What are the official names of this protein?
D-galactonate dehydratase, GalD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: CONA3_LUPAN
Sequence: MANPFLLSLSLCLVLLYTSACLGEGLDRFNECQLDRLNALEPDNRIESEGGVTETWNSNKPELRCAGVAFEKHTIEPKGLHLPSYTNYPQIIMIVQGEGALGISVPGCTETFEEAQQSQSRQERRRGQRSQSQEQEDSHQKIRHFREGDILVIPPGTPYWTYNYGDEQLVAINLLDTTSLSNQLDPNPRRFYLAGNPEEEYPETQQQRQQRQQHQRPSGRRHGQHQKEEEQEGKNNILSGFDPQFLSQALNIDEDTVHKLQNPNERIKQIIRVEEGLGVISPKWQEQEEEEEEKEEPRQRRRRERREEREEEEKEEEDEPRESRRHRGGHEEEEVEEERGRGRGGSEWKRTTRRRHTRGDEGQEEEETTTTTEERRRRRGGRGSRQEEEEEQSPPRSRNGLEETICTAILRENIADPTRADLYNPTAGRISTANSLTLPILGWFQLSAEYVNLYRNGIYAPHWNINANSVIYVIRGRGRVQVVNSQGNSVFNDDLRRGQLLVVPQNFVVAHQAGDEGFEFIAFKTNDQATTSPLKQVFRGIPAEVLANAFRLSLNQVSELKYNGNHNPLVTPQSQSQDHNLVKVA
What is the function of this protein?
Sulfur-rich seed storage protein.  This protein found in the seeds of many leguminous and non-leguminous plants is the source of sulfur-containing amino acids in seed meals.
What are the official names of this protein?
Conglutin alpha 3.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: KUP_ECO8A
Sequence: MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS20_RICRS
Sequence: MANHSSAKKAARQTVKRTLINKKRSSAIKTFIKKVVHEISLGNKENANIALSVAQSKIMQGVKKNIIKLNTASRKISRLSRQIKSLKVNNTL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: NFI_ECOLI
Sequence: MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLAWVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRYTANQP
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.  Has a wide substrate spectrum.  In addition to deoxyinosine-containing DNA, the enzyme cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures.  Participates in the excision repair of hypoxanthine and xanthine (deaminated adenine and guanine) in DNA.  It thereby reduces the mutagenic effects of nitrous acid by attacking lesions caused by nitrosative deamination.  Also active on inosines in single- and double-stranded RNA.  May cleave tRNA(Arg2), which contains inosine at the wobble position.
What are the official names of this protein?
Endonuclease V, EndoV, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_VIBVY
Sequence: MAAPGEALTPSGYITHHLTNLSTYKLGLVAEESSFWNVHIDSLFFSWFTGLIFLGIFYAVARKTTAGVPGKLQCAVEMIVEFVATNVKDTFHGRNPLIAPLALTIFCWVFLMNLMDLVPIDFLPYPAEHWLGIPYLKVVPSADVNITMAMALGVFALMIYYSIKVKGLGGFARELALHPFNHWTMIPFNLLIEVVSLLAKPLSLGMRLFGNMFAGEVVFILCAAMLPWYLQWMGSLPWAIFHILVILIQAFVFMMLTIVYMSMAHEDSDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RR8_PSINU
Sequence: MSHDTIADMISLVRNANMRKAVKVRVPATGITQNIVKILLQEGFIKDYMKQEKRTRSFFILTLKYQGRVRKPHITAFKRISKPSLRIYSNYQKITRILGGMGIAIISTSSGIMTDREARQKRLGGEIICHVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUCS_BIFAA
Sequence: MRIIVADCSAEYSERLNASLPLAKRVLLIKADNSLLIFSELGSYKPLNWMSAPCSIRDITPDHADDDVDTEVPQKVIRASADKSNDVLEVTLQRIYSDESYDLGEDPGLIKDGVEDHLQKYLAEQIERIGKGAKLVRREYPTAIGPVDIMAIDGNGEHVAIEIKRNGGIDGVEQLTRYCDLLNRDPLLAPVHGIFAAQTITPQARVLAQDRGFKCLLLDYEEMKGTEDDSLRLF
What is the function of this protein?
Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.
What are the official names of this protein?
Endonuclease NucS.
What is the protein family that this protein belongs to?
Belongs to the NucS endonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_MEGSP
Sequence: MNPLASIMITLTIILGTMIVMTSSHWLLVWIGFEMNMLAIIPVLMKQHSPRAVEAATKYFLTQATASMLLMLAVVTNLLYSGQWTVTNITNPLASAVMTLALVMKLGLSPFHFWVPEVAQGIPLSSGLVLLTWQKLAPLSVLYQISHSVSPTLLLTVSLMSIAVGGWGGLNQTQLRKILAYSSIAHMGWMTAVLAYNPTLTLLNLTLYILMTTTTFLLFMFNSSTTTLTLSHSWNKSPMIATSTLTIMLSLGGLPPLTGFLPKWMIIQELTKNESLLLPTLMAMMALLSLYFYMRLTYSTSLTLFPSMNNTKMKWHLNNTKKVPLLPPMITLFTLALPLAPALSTLY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL4_LACE2
Sequence: MANVSVYNIEGKEVGSIELNDAVFGVEVNEHLVHMAVVNQLANNRQGTQSAKTRSEVSGGGRKPWRQKGTGHARQGSTRSPQWTGGGVVFAPKPRDYSFKMNKKEKRIALLSALSSKVADNKIVVLDAFNLDEIKTKKFAEVMSNLKVDKALVVIEGENKNVVLSGRNIPTVKVSATNEINTYDVLKYETLVVTKAAVEKLEEVYA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: UVRB_YERPG
Sequence: MSKSFKLHSVFKPAGDQPEAIRKLEEGLENGLAHQTLLGVTGSGKTFTVANVIADLNRPTMILAPNKTLAAQLYGEMKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKALLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTRGMIIDQRSILRRLSELQYSRNDQVFQRGTFRVRGEVIDIFPAESDEWALRVELFDEEVERLSIFDPLTGQLQHEVPRFTVYPKTHYVTPRERILQAMEEIKVELAERRQVLLANNKLLEEQRLSQRTQFDLEMMNELGYCSGIENYSRYLSGRGPGEAPPTLFDYLPADGLLIVDESHVTIPQIGGMYKGDRSRKETLVEYGFRLPSALDNRPMRFEEFEALAPQTIYVSATPGKYELEKSGGDIIEQVVRPTGLLDPLIEVRPVATQVDDLLSEIRIRAAINERVLVTTLTKRMAEDLTDYLSEHGAKVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLNGKAILYGDRITASMEKAIGETERRRAKQQAYNEERRIIPQGLNKKIGDILQLGQPSMRGKGKGRGSHKMADTTQYQSLSPKALDQKIRELEAKMYTYAQNLEFEQAAELRDQVHQLRQQFIAIS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_LYSSC
Sequence: MKHRYLPMTEQDQKEMLDVIGVSSVDELFEDIPEKVRFKGLYDIKAAKSESALLKELTALAAKNKDTNANVSFLGAGVYNHYKPVIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMIAELTGMDLANSSMYDGGTALAEAGMLAAGHTRRKKILVSETVHPEYRDVVATYAYGQSIEIVTIPHKDGVTDIAALKELIDDNTAAVIAQYPNFFGQVEDIQVIGDIAHEAKSLFVVSSNPLALGILTPPGKLGADICVGDAQVFGISEAFGGPHCGFFAVTTKLMRKVPGRLVGETVDGEGRRGYVLTLQAREQHIRRDKATSNICSNQALLALAASVAMTALGKQGIREMATQNIAKTRYAKNAFEAAGFTVAFQGAHFNEIVVKTNKCVKEINKGLIEKGIIGGYPLGQNYDSLKHHVLIAVTELRTKEEIDALVAEMGALHA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: PLSX_BLOPB
Sequence: MVIALDAMGGDFGPVVTVPASLQALSLYPKLRLLLVGNPDAILPILATSKSIGLDRLTVIPARSVISGDARPSQAIRVSKDTSMRVALELIKSGRAHACVSAGNTGALMGLSKLVLKSVHGIERPALTTLLPHQKQGKTVILDLGANISCDGAMLVQFAIMGSVLSKQILGVSNPRVALLNIGSEETKGLDNIRHASRILHTISSIHYVGYVEANDLLMGKTDVLVCDGFIGNITLKTMEGVIRVILSTLQSSEKKNKLNWFMQIINSWIRKYLFKQFNQFNPDWYNGAHLVGLRSTVIKSHGAANQHAFIAAITQAMHSVEREVPEKISHQLSTVLSKNNH
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.