PharMolix/UniProtQA huggingface dataset:
Protein: WECF_SHIF8
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHVAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASADKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BASI_BOVIN
Sequence: MAAALFVLLGFALLGTHGASGAAGTVFTTVEDLGSKILLTCSLNDSATEVTGHRWLKGGVVLKEDALPGQKTEFKVDSDDQWGEYSCVFLPEPMGTANIQLHGPPRVKAVKSSEHINEGETAMLVCKSESVPPVTDWAWYKITDSEDKALMNGSESRFFVSSSQGRSELHIENLNMEADPGQYRCNGTSSKGSDQAIITLRVRSH
What is the function of this protein?
Signaling receptor for cyclophilins, essential for PPIA/CYPA and PPIB/CYPB-dependent signaling related to chemotaxis and adhesion of immune cells (By similarity).  Plays an important role in targeting the monocarboxylate transporters SLC16A1/GLUT1, SLC16A3, SLC16A8, SLC16A11 and SLC16A12 to the plasma membrane (By similarity).  Acts as a coreceptor for vascular endothelial growth factor receptor 2 (KDR/VEGFR2) in endothelial cells enhancing its VEGFA-mediated activation and downstream signaling (By similarity).  Promotes angiogenesis through EPAS1/HIF2A-mediated up-regulation of VEGFA and KDR/VEGFR2 in endothelial cells (By similarity).
What are the official names of this protein?
Basigin, EMMPRIN.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein.
Protein: HTPX_VEREI
Sequence: MKRILLFVLTNLAVVLVLGVVASLLGVNHYLTGNGLNLGALLGFALVMGFGGAFISLLISKPMAKWSAGVRVIDGSGSPDERWIVETVRKLASQAGIGMPEVGIFDGAPNAFATGAFKNSALVAVSTGLLQGMTREEVEAVIGHEVAHIANGDMVTMTLIQGVMNTFVVFLSRVIGYAVDSALRKNNDSQTGPGMGYYVTTIVLDIALGFVAAIIVAWFSRQREFRADAGAARLMGRRQPMIAALARLGGMQPAQLPKSMAALGIAGGIGQWFSTHPPLEARIAALQNAHQD
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ESXJ_MYCTU
Sequence: MASRFMTDPHAMRDMAGRFEVHAQTVEDEARRMWASAQNISGAGWSGMAEATSLDTMTQMNQAFRNIVNMLHGVRDGLVRDANNYEQQEQASQQILSS
What are the official names of this protein?
ESAT-6-like protein EsxJ.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: T2R16_PANPA
Sequence: MIPIQLTVFFMIIYVLESLTIIVQSSLIVAVLGREWLQVRRLMPVDMILISLGISRFCLQWASMLNNFCSYFNLNYVLCNLTITWEFFNILTFWLNSLLTVFYCIKASSFTHHIFLWLRWRILRLFPWILLGSLMITCVTIIPSAIGNYIQIQLLTMEHLPRNSTVTDKLEKFHQYQFQAHTVALVIPFILFLASTILLMASLTKQIQHHSTGHCNPSMKAHFTALRSLAVLFIVFTSYFLTILITIIGTLFDKRCWLWVWEAFVYAFILMHSTSLMLSSPTLKRILKGKC
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 16, T2R16.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YQO4_SCHPO
Sequence: MSTSYLCDENRKGENRKVEIQELVPYLYSVLLRGVPSRPVFDSRLKFAVKVPVYPKRPLYTTDTRTHYYLKNCFRILEWEIVSHVGGNELLINRRVIDVNNFFICQDANSGPFCTAWRFTH
What are the official names of this protein?
Uncharacterized protein C569.04.
Protein: HXCAA_TAKRU
Sequence: MSCPNNSGNFLMDPLMGGSSSFRDEGYSSNSGMYIHTAAECGYSVMKVEPSPLSKSRDVPAGSVLLSSFQDAPYLSAQPSTWTPGTKSSRDQQLVAQCLQPCSFPAGNVKEEAFCCFYQDGSKRKQTTESATYIRLRDNRCGPEQTTTQARGCFQMYNREEPQQDDQLFAPACSLLHLGTSVESQSKISCSKFATETGKDERKEEKARSDGCSETSDNEELKGRNLQSQRTLFLCLNVSAILLRNSRVLVFGNSHDASSEKTTGNWLKAKSGRKKRCPYTKHQTLELEKEFLFNMYLSRERRLEISRSINLTDRQVKIWFQNRRMKLKKLNRESREREQGVVYNYC
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C10a.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOB_MOOTA
Sequence: MAVTRLKPADPQIPDNIILSTVDAMLNYCRAHSFWPVTFGLACCAIEMMAAGGARYDIARFGYEVFRPSPRQADLMIVAGTVTRKMAPLVRRLYEQMPAPKWVIAMGSCAISGGPFVDSYNVVPGVDTIVPVDVYVPGCAPRPEALINGLLALKKKVINPKVALVK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KATG_SERP5
Sequence: MTTESKCPFSGGGKPNTPRRGPSNQDWWPNQLSLKPLHQHSSLSDPMDPDFDYAKAFNSLDLAAVKQDLHALMTDSQEWWPADFGHYGGLFIRMAWHSAGTYRIGDGRGGAGEGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGRKISWADLIVLTGNVALESMGFKTFGYAGGRADTWEPDDVYWGSEKIWLELSGGQNSRYSGDRDLEDPLAAVQMGLIYVNPEGPDGNPDPVAAARDIRETFARMAMNDEETVALIAGGHTFGKTHGAGPASHVGDDPETAGLERQGLGWQSSFGTGKGKDAITSGLEVTWTTTPTQWNHDFFKHLFEYEWELTQSPAGAHQWVAKDVGETIPDAFDPAKKQRPTMLTTDLSLRFDPAYEKISRRFYEHPDQLADAFSRAWYKLTHRDMGPRARYLGPEVPAEELIWQDPIPAVDHQLINDQDIADLKTSILTSGLPISVLVSTAWASASTFRGSDKRGGANGARIRLAPQKDWAINQPAQLAQTLAKLEDIQQAFNNAQSGNKRVSLADLIVLAGAAAVEQAAANAGHPVSVPFTPGRMDATQEQTDVDSFEAMEPVADGFRNYLERQFNIPAEALLVDKAQLLTLTAPEMTVLVGGLRVLNANVGQSQHGVLTQRPQALSNDFFVNLLDMGTTWKAAGEDGVFEGQDSQTGALKWTATRADLIFGSHSQLRALAEVYGSSDAQASFVYDFVAAWNKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: MINE_SYNJB
Sequence: MLLDFLDQLFSRHSGNSRQQAKQRLKLILAHDRADLTPAALESMRLEILGVVSRYVELDSEGMQFHLATEGGTTALIANLPIRRVKPLETGLSRSEGEKA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RISB_CAMLR
Sequence: MKIIEGNLSLKGDEKIAIINARFNHIITDRLVEGAKDAFLRHGGKEENLSLILVPGAFEIPFALKQACESKKFDGICCVGAVIRGSTPHFDYVAAETTKGIASVGLGANVPVSFGVLTTDTLEQAIERAGSKAGNKGFEAMLTVVEMLNLIQKIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: THIC_DEHMC
Sequence: MTQLKQARKGIVTPEMEAVAKTEGLQPEFILKGIADGNIVIPANKLRKNLKLCGIGKGLSTKVNANIGTSTDFGSVASEVEKLKMAEMVGADTIMDLSTGPKINTIRKAILENTCLPLGTVPVYQAAVEAKDHYGAMVKMTADDLFGAIESQAKEGVDFVTVHCGVTRQVIDTFKGQGRLTDIVSRGGTFTAGWMVFHGAENPLYEHFDRLLDICREYDVTLSLGDGLRPGCIADATDRAQVAELLVLGELVKRAREAEVQVMVEGPGHVPLNQIEANVRLQKSICEDAPFYVLGPLVTDIAPGYDHITGAIGGAIAAAAGADFLCYVTPAEHLSLPDVTDVRNGVIASRIAAHAADIVKGVNGAAERDHQMAIARKKLDWETQLKLSLDPEHARVTRDRFKTRGKACSMCGDFCAMELAEKHLGVSVSRC
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: ACCD_METNO
Sequence: MKVETMNWISEVVRPRIKTLFKRETPENLWVKCPETGQMVFHKEVEANDYVIPGSEHHLRMTAQQRLKMMFDQGTWLDVPLPEVPVDPLKFRDEKRYVDRLKDARAKTGMMDAFKVGFGRVGGLPMTLAVQDFGFMGGSLGMAAGEAFVRGAETALDKRTPYVLFAASGGARMQEGILSLMQMPRTTVAVRRLNQARLPYLVVMTNPTTGGVTASYAMLGDIHLAEPGALIGFAGPRVIEQTIREKLPDGFQRSEYLREHGMIDQVVHRRDLKATIARLCGLLMQAPAAEPAEEEAEPLPA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL41_AGABI
Sequence: MREKWKKKRSRRLRRKRRKMRARSK
What are the official names of this protein?
60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL41 family.
Protein: RL25_BORBZ
Sequence: MENSRVLSCQYRSSFGSSNARRIRAKSEIPAVVYGQGKDVSHLRIKSSEFNKKFAKFTDNTVLILDDGKLERCVFVKDVAENIASKLIYHIDFYEVDRNVELEKYVPIKLIGASIGVKEGGILTVLKEQVKVRSLPLDLPEFIELDLTPVNKGDSVLLKDLVLPSNVRLAENDENLEVVIIK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: PURA_BURTA
Sequence: MSASAVNVTPGRNVVVVGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLIIGGKKTILRLIPSGIMREGVACYIGNGVVLSPEALFKEIGELEEAGLSVRERLFISEATTLILPYHIAIDQAREARKGAGKIGTTGRGIGPAYEDKVGRRALRVQDLFDARTFADRLRENLDFHNFVLTQYLGGAAVDFQATLDTMLGYADRLRPMVADVSRRLYEENHAGRNLLFEGAQGTLLDIDHGTYPFVTSSNCVAGAAAAGAGVGPQKLNYILGITKAYCTRVGSGPFPSELYDADNPSRQDQIGITLANVGKEFGSVTGRPRRTGWLDAAALRRSIQINGVSGLCMTKLDVLDGLDEVKLCVGYKIDGEDADLLPRGAAEVARCEPVYETFGGWKESTVGINSWDALPANARAYLTRVQEVAGVPIDMVSTGPDRDETILLRHPFKV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECP_APICC
Sequence: MKNYSKNATYLITVLLFSFVAMLLIIPSKCEAVSNDMQPLEARTADLVQQPRYIIDVPPRCPPGSKFVHKRCRVIVP
What is the function of this protein?
Nontoxic peptide.
What are the official names of this protein?
Secapin.
What is the protein family that this protein belongs to?
Belongs to the secapin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR11_ANGEV
Sequence: MAKPIRKIGLRKGKRKIPKGVIHIQASFNNTIVTVTDIRGQVVSWSSAGACGFKGTRKSTPFAAQTAAENAIRTLIDQGMKQAEVMISGPGPGRETALRAIRRSGVVLSFVRDVTPMPHNGCRPPKKRRV
What are the official names of this protein?
30S ribosomal protein S11, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GCH1L_MYCLE
Sequence: MSARLADVIEVLDHAYPPRFAQSWDSVGLVCGDPEDVLEAITIAVDATPAVIDEVPDSGLLLVHHPLLLHGVDTVAVSTPKGALVHRLIRSGRSLFTAHTNADSASPGVSDALAHVFGLTVDAVLEPLLGVASLDKWVIYVPLEHVAAVQAAVFEAGAGHIGDYSHCSWSVTGTGQFMPHDGASPVVGSIGAIERVAEDRVEVVAPARARAAVLSAMHAAHPYEEPAFDIFALVPPPGDVGLGRIGTLPRPESLSAFVARVGAALPQTSSGVRATGDPDMLVSRVAVCGGAGDSLLSLAAVADVQAYVTADLRHHPADEHRRASNVALIDVAHWASEFPWCGQAADVLRSHFGTALSVRVCTIRTDPWNLGARRVNDVSDSGRDQ
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: CYSC_ECOL5
Sequence: MALHDENVVWHSHPVTPQQREQHHGHRGVVLWFTGLSGSGKSTVAGGLEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: XDH2_ARATH
Sequence: MEQNEFMEAIMYVNGVRRVLPDGLAHMTLLEYLRDLGLTGTKLGCGEGGCGSCTVMVSSYDRESKTCVHYAVNACLAPLYSVEGMHVISIEGVGHRKLGLHPLQESLASSHGSQCGFCTPGFVMSMYALLRSSKNSPSEEEIEECLAGNLCRCTGYRPIIDAFRVFAKSDDALYSGLSSLSLQDGSNICPSTGKPCSCGSKTTSEAATCNEDRFQSISYSDIDGAKYTDKELIFPPELLLRKLAPLKLGGNEGITWYRPVSLQNLLELKANFPDAKLLVGNTEVGIEMRLKRLQYPVLISAAQVPELNALNVNDNGIEVGSALRLSELLRLFRKVVKERPAHETSACKAFIEQLKWFAGTQIRNVACIGGNICTASPISDLNPLWMASRAEFRIINCNGDVRSIPAKDFFLGYRKVDMGSNEILLSVFLPWTRPLEYVKEFKQAHRRDDDIAIVNGGMRVFLEEKGQQLFVSDASIVYGGVAPLSLRARNTEELLIGKNWNKCLLQDALKVIQSDVLIKEGAPGGMVEFRKSLTLSFFFKFFLWVTHHVNNVNPTIETFPPSHMSAVQLVPRFSRIGKQDYETVKQGTSVGLPEVHLSARMQVTGEAEYTDDTPLPPCTLHAALVLSKVPHARILSVDDSAAKSSSGFVGLFLAKDVPGNNMIGPIVADEELFATDVVTCVGQVIGVLVADTHENAKTAARKVDVRYQELPAILSIKEAINAKSFHPNTERRLRKGDVELCFQSGQCDRIIEGEVQMGGQEHFYLEPNGSLVWTIDGGNEVHMISSTQAPQQHQKYVSHVLGLPMSKVVCKTKRLGGGFGGKETRSAFIAAAASVPSYLLNRPVKLILDRDVDMMITGHRHSFVGKYKVGFTNEGKILALDLEIYNNGGNSMDLSLSNLERAMFHSDNVYEIPHVRIVGNVCFTNFPSNTAFRGFGGPQGMLITENWIQRIAAELDKIPEEIKEMNFQVEGSITHYFQSLQHCTLHQLWKELKVSSNFLKTRREADEFNSHNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVTHGGVEMGQGLHTKVAQVAATAFNILLSSVFVSETSTDKVPNASPTAASASSDMYGAAVLDACEQIIARMEPVASKHNFNTFSELASACYFQRIDLSAHGFHIVPELEFDWVSGKGNAYRYYTYGAAFAEVEIDTLTGDFHTRKADIMLDLGYSLNPTIDIGQIEGAFVQGLGWVALEELKWGDAAHKWIKPGSLLTCGPGSYKIPSINDMPFQLNVSLLKGNPNAKAIHSSKAVGEPPFFLAASAFFAIKEAIKAARSEVGLTNWFPLETPATPERIRMACFDEFSAPFANSDFCPKLSV
What is the function of this protein?
Key enzyme involved in purine catabolism.  Catalyzes the oxidation of hypoxanthine to xanthine and the oxidation of xanthine to urate.  Regulates the level of ureides and plays a role during plant growth and development and senescence.
What are the official names of this protein?
Xanthine dehydrogenase 2, AtXDH2.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
Protein: TRPB_BRUC2
Sequence: MNKPVAPNSYKTGPDEEGMFGIFGGRFVAETLMPLILELQQAYETAKNDPEFKAELNALSTFYAGRPSKLYYAEGLSKHLGGAKIYFKREDLNHTGSHKINNCLGQILLAKRMGKTRIIAETGAGQHGVASATVAARFGLPCIVYMGATDVERQKPNVFRMKLLGAEVKPVSAGNGTLKDAMNEALRDWVTNVEDTYYLIGTAAGPHPYPELVRDFQSVIGTEARQQILEQEGRLPDVIVAAVGGGSNAIGLFHPFLDDASVKIVGVEAGGRGLEGEEHCASMSAGRPGVLHGNRTYLLQNADGQILEGHSVSAGLDYPGVGPEHSWLKDSGRVDYVPILDNEALDAFQLCTRTEGIIPALESAHAIAQAVKMAPTMGKDKVMIVNLSGRGDKDVHTVGKLLGMDI
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: FAN_HUMAN
Sequence: MAFIRKKQQEQQLQLYSKERFSLLLLNLEEYYFEQHRANHILHKGSHHERKIRGSLKICSKSVIFEPDSISQPIIKIPLRDCIKIGKHGENGANRHFTKAKSGGISLIFSQVYFIKEHNVVAPYKIERGKMEYVFELDVPGKVEDVVETLLQLHRASCLDKLGDQTAMITAILQSRLARTSFDKNRFQNISEKLHMECKAEMVTPLVTNPGHVCITDTNLYFQPLNGYPKPVVQITLQDVRRIYKRRHGLMPLGLEVFCTEDDLCSDIYLKFYEPQDRDDLYFYIATYLEHHVAEHTAESYMLQWQRGHLSNYQYLLHLNNLADRSCNDLSQYPVFPWIIHDYSSSELDLSNPGTFRDLSKPVGALNKERLERLLTRYQEMPEPKFMYGSHYSSPGYVLFYLVRIAPEYMLCLQNGRFDNADRMFNSIAETWKNCLDGATDFKELIPEFYGDDVSFLVNSLKLDLGKRQGGQMVDDVELPPWASSPEDFLQKSKDALESNYVSEHLHEWIDLIFGYKQKGSDAVGAHNVFHPLTYEGGVDLNSIQDPDEKVAMLTQILEFGQTPKQLFVTPHPRRITPKFKSLSQTSSYNASMADSPGEESFEDLTEESKTLAWNNITKLQLHEHYKIHKEAVTGITVSRNGSSVFTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDATVITSSWDNNVYFYSIAFGRRQDTLMGHDDAVSKICWHDNRLYSASWDSTVKVWSGVPAEMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQIPCHSGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTSDEPQRCFVWDGNSVLSGSQSGELLVWDLLGAKISERIQGHTGAVTCIWMNEQCSSIITGGEDRQIIFWKLQY
What is the function of this protein?
Couples the p55 TNF-receptor (TNF-R55 / TNFR1) to neutral sphingomyelinase (N-SMASE).  Specifically binds to the N-smase activation domain of TNF-R55.  May regulate ceramide production by N-SMASE.
What are the official names of this protein?
Protein FAN, Factor associated with neutral sphingomyelinase activation, Factor associated with N-SMase activation.
Protein: MRAZ_LISMH
Sequence: MFMGEYQHNIDIKGRLIVPAKFRELLGDNFVITRGLDKCLFAYPQEEWKKLEEKLQTLPLTKKDARSFTRFFFSGASECELDKQGRINIPSNLLQYADLEKETVIIGVSSRIEIWSKSEWDDVFNEAEESFADLAENMIGFDI
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NISI_LACLL
Sequence: MRRYLILIVALIGITGLSGCYQTSHKKVRFDEGSYTNFIYDNKSYFVTDKEIPQENVNNSKVKFYKLLIVDMKSEKLLSSSNKNSVTLVLNNIYEASDKSLCMGINDRYYKILPESDKGAVKALRLQNFDVTSDISDDNFVIDKNDSRKIDYMGNIYSISDTTVSDEELGEYQDVLAEVRVFDSVSGKSIPRSEWGRIDKDGSNSKQSRTEWDYGEIHSIRGKSLTEAFAVEINDDFKLATKVGN
What is the function of this protein?
Involved in immunity against exogenously supplied nisin.
What are the official names of this protein?
Nisin immunity protein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GMPPB_MOUSE
Sequence: MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQMLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPAVLQRIQLKPTSIEKEIFPVMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKHPERLYSGPGIVGNVLVDPSARIGQNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDAHIRSHSWLESCIVGWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPRIIM
What is the function of this protein?
Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids.
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase beta, GDP-mannose pyrophosphorylase B, GTP-mannose-1-phosphate guanylyltransferase beta.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTG2_AVIVO
Sequence: MKINAMSLFSSAGIGELDLHKGNLNFVVANELLKKRADTYQFFYPETKMFQGDISDEKLKREILLSAQQNNVKFLLATPPCQGLSSVGKNKHQDHFIKDNRNFLIFEVFEFIDVLNLDFILIENVPRFIEMYFPYNGQLLLLEEILKIKYASKYQIDIVILNAKDYGICQSRPRAIIKMYKYGITWKLPTIQAEISLQRAIGHLPPLEPGEVSSIKWHSAPNVKPSIIEAIRHTKPGTSAISNPIFYPKKDNGERIKGFHNTYKRMEWDKPAPARTTYSGSISSHNNIHPGRLQLDGTYSDPRVLSLLETFIVSSIDENIEFPPGSSETYIRTIIGEAIPPKLLSAICFPDGENINVK
What is the function of this protein?
A methylase that recognizes DNA with the sequence 5'-GACGC-3', methylates C-3, and protects the DNA from cleavage by the HgaI endonuclease.
What are the official names of this protein?
Type II methlytransferase M2.HgaI, M2.HgaI, Cytosine-specific methyltransferase HgaIB, M.HgaI-2, Modification methylase HgaIB, M.HgaIB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: Y3679_MYCTU
Sequence: MVATTSSGGSSVGWPSRLSGVRLHLVTGKGGTGKSTIAAALALTLAAGGRKVLLVEVEGRQGIAQLFDVPPLPYQELKIATAERGGQVNALAIDIEAAFLEYLDMFYNLGIAGRAMRRIGAVEFATTIAPGLRDVLLTGKIKETVVRLDKNKLPVYDAIVVDAPPTGRIARFLDVTKAVSDLAKGGPVHAQSEGVVKLLHSNQTAIHLVTLLEALPVQETLEAIEELAQMELPIGSVIVNRNIPAHLEPQDLAKAAEGEVDADSVRAGLLTAGVKLPDADFAGLLTETIQHATRITARAEIAQQLDALQVPRLELPTVSDGVDLGSLYELSESLAQQGVR
What are the official names of this protein?
Putative ATPase Rv3679.
Protein: ERN2_MOUSE
Sequence: MARPVQRFQLWSPLGFLLQLVTLLGKLGPQVQSVRPESLLFVSTLDGSLHALNKQTGDLKWTVKDDPIIQGPMYVTEMAFLSDPADGSLYVLGTQKQQGLMKLPFTIPELVHASPCRSSDGVFYTGRKQDAWFVVDPESGETQMTLTTEGLSTPQLFIGRTQYTVSMHDLRTPALRWNTTYRRYSAPLLNGSPGKYMSHLTSCGMGLLLTVDPGSGIVLWTQDLGVPVTGIYTWHQDGLHQLPHLTLARDTLHFLVLRWGHIRLPASSYQDTATQFSSLDTQLLMTLYVGKEEAGFYVSKALVHAGVALVPRGLTLAPMDGPTTDEVTLQVSGEREGSPSTAVRYPSGSVALPSQWLLIGYHEPPPVLHTTMLRVHPIPGKVSAETRASEDLHAPPVFFELLNLRREDPELHPEEKASDSYPGLGSQDLLAATFTAILLGAWVLYLMRQQQQSPSAPAGPPDLSQDAQGQLSRDILQDQRRFQSPSEPAQPPHDPEAGQPTVVGKISFNPKDVLGRGAGGTFVFRGQFEGRAVAVKRLLRECFGLVRREVQLLQESDRHPNVLRYFCTEHGPQFHYIALELCQASLQEYVESPDLDRWGLEPTTVLQQMMSGLAHLHSLHIVHRDLKPANILMAGPDSQGQGRVVISDFGLCKKLPVGRCSFSLHSGIPGTEGWMAPELLQLPPDSPTSAVDIFSAGCVFYYVLSGGSHPFGESLYRQANILSGDPCLAQLQEETHDKVVALDLVRAMLSLLPQDRPSAGWVLAHPLFWSRAKELQFFQDVSDWLEKEPDQGPLVSALEAGSYKVVREDWHKHISAPLQADLKRFRSYKGTSVRDLLRAMRNKKHHYRELPAEVRQTLGQLPAGFIQYFTQRFPRLLLHTHRAMRTCASESLFLPYYPPALEARRPDATKS
What is the function of this protein?
Role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis.  Has no effect on 28S ribosomal RNA cleavage, unlike the corresponding human protein.
What are the official names of this protein?
Serine/threonine-protein kinase/endoribonuclease IRE2, Endoplasmic reticulum-to-nucleus signaling 2, Inositol-requiring protein 2, Ire1-beta, IRE1b, mIre1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: MLTG_BACSU
Sequence: MYINQQKKSFFNKKRIILSSIVVLFLIIGGAFLYGKSLLEPVEKDSKTTVNINIPSGSSVSAIASILKKNDVIKSEKAFQYYVKYKGASGFQAGFYHLNKGMDLDAIIQKLTSGATGYAFQITVTEGAQLTQIAAAIADETKYSKKQVIAKLDDETFINQLKKEFPDTVTNDVFNKNIKHPLEGYLFPATYPFNDPDTSLEDIIKAMIKQTNSYVETYKSEMKKNKVSVHKLLTMASLIEEEATEKADRHKIASVFYNRLKKKMPLQTDPTVLYAAGKHKDRVLYKDLEIDSPYNTYKNTGLTPGPIANAGMSSWEAALHPDKTDYLYFLAKSNGEVVFTKTLKEHNKAKEKYISSKNEK
What is the function of this protein?
Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
What are the official names of this protein?
Endolytic murein transglycosylase, Peptidoglycan polymerization terminase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase MltG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.