PharMolix/UniProtQA huggingface dataset:
Protein: THIO_SYNY3
Sequence: MSATPQVSDASFKEDVLDSELPVLVDFWAPWCGPCRMVAPVVDEISQQYEGKVKVVKLNTDENPNTASQYGIRSIPTLMIFKGGQRVDMVVGAVPKTTLASTLEKYL
What is the function of this protein?
Component of the thioredoxin-thioredoxin reductase system.  Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: DNAJ_ACISJ
Sequence: MSKRDFYEVLGVPKNASDDEIKKAYRKLAMKYHPDRNQGDAAKPAEEKFKEAKEAYEILSDAQKRAAYDQYGHAGVDPNMRGGMGGAEGFGGFAEAFGDIFGDMFGGARGRGGRQVYRGNDLSYAMEITLEEAAKGKEAQIRIPSWESCETCHGSGAKPGTSAKTCGTCQGSGTVQMRQGFFSVQQTCPHCRGTGKIIPEPCTACHGQGRVKKQKTLEVKIPAGIDDGMRIRSTGNGEPGTNGGPPGDLYIEIRIKKHDIFERDGDDLHCQVPVSFITAALGGEIEVPTLQGKAAIDIPEGTQAGKQFRLRGKGIKGVRSSYPGDLYCHIIVETPVKLTEHQRKLLKELDESLKKGGAKHSPSTESWTDRLKSFFS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP13_FRATH
Sequence: MMTLQEEKIQAPVFFKEYVKGRFILNIGEYNHPLILSATQVLEYQDKIDDIQSIKKSHLDLILATNPEIILIGTGEKQLLPPLEIINQIAKAGKSVDFMASDTACKTYNLLVNENRNVSCIII
What are the official names of this protein?
13 kDa major membrane protein.
What are the subcellular locations of this protein?
Cell membrane.
Protein: CYMC6_MELCT
Sequence: GVIPCGESCVFIPCISSVVGCTCKNKVCYRN
What is the function of this protein?
Probably participates in a plant defense mechanism (Potential).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (By similarity).
What are the official names of this protein?
Cyclotide mech-6.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: HIS4_META3
Sequence: MIVIPAVDIKNKKCVQLIQGNPDKKHIELDNPLEVAEKWIKCGAEMIHLVDLDSAIYGTDTNKETIKKIIESVPVPVEVGGGVRTVEDALNLIDLGAERVILGTSAVKNPEIITELLEKGINSEKIMVALDAKDGKVVIKGWMEKTEYTPIEIGKILEEKGAGSILFTNVDVEGLLDGIDIEPVKKLVDELNIPIIASGGITTYDDLLKLKEIGVDGVVVGSAIYKEMMDLKKAIKIVKGE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y872_STAA3
Sequence: MLHLHILSWVLAIILFIATYLNISKNQGRSPFFKPLHMILRLFMLLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWITIALIIITMVLGVILPLGPISKLFGIG
What are the official names of this protein?
UPF0344 protein SAUSA300_0872.
What is the protein family that this protein belongs to?
Belongs to the UPF0344 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SERC_SHEAM
Sequence: MSAVYNFCAGPAMLPAAVMKKAQAELLDWNGQGVSVMEVSHRGAPFIQLAKDSEADLRELMNIPDNYHVLFMHGGGRGQFSAVVNNFLGDNGKALYLVSGQWSKAATEEAKKLAGDNSIDVINVVEKVNGLNKVVIPALSGNGSEYRYLHYCPNETVDGIEIFDDIDSPWPIVADMSSNIMSREIDVSRFALIYAGAQKNIGPSGLSIVIVRKDMLELPQLTQSSIMDYRLTAENDSMYNTPPTFAWYLAAEVFKWLKSVGGIKGMAEVNAEKARRLYACIDSLDFYKNGVAPQNRSQMNVTFQLADESLDKDFLKEAEALGLVALKGHRIVGGMRASIYNAMPLEGVDALVSFMRSFAAKHSS
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_ENT38
Sequence: MSHPALTQLRALRYFDQIPALSPEQLDWLLLEDSMTKRFEQQGKNVTVTLIQEGFVSSDEVSSELPLLPKEERYWLREILLCADGEPWLAGRTVVPESTLSGPELALQTLGKTPLGRYLFTSSELTRDFIEIGRDADLWGRRSRLRLSGKPLMLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_GEOUR
Sequence: MAKVDVISRVTVLAEQVISSLGMELVDLEYKREGREMVLRLFVDKEGGVNLDDCASVSRELSEVLDVEDVISEHYSLEVSSPGIDRPLKKVEDFQRFKGRLVKIRTFEPLPDDAGNKRKTFLGELKGIENGVVLVALKEGQNAAIPFEKVAKANLEFEF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_CUPNE
Sequence: MEPFTMHRGVAAPLLRINIDTDAIIPSREMKRVSRHGLAEGLFAGWRYLAGTDRSPDPLFVLNQPEYTGASILLAGSNFGCGSSREHAVWALKEFGIRAIVAPGFGAIFHNNCVRNGLLPVVLPMATVQALADDCAAAPATRQVTVDLRQLEVVSPAGARYGFTLGSEQRQMLLEGLDPIALTLKLASSIDAFQGADRLRRPWIHFDG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: FABH_CLOBM
Sequence: MSNISVIGTGSYVPNDIITNDFLSTIVDTSDEWIRTRTGILERRISKEENTIYMATESAKEAIKNANIDANDLDLIIVATLTPDNFMPSTACSVQKEIGAINALCFDISAACSGFIYGLEIACSMLKNSFRNKALIIGAENLSKIVDWEDRNTCVLFGDGAGAAILSKTKEEGILEFHSGSNGLKGEHLTCGVLKANNTSNKNDRLEKNNFIKMNGKEIFRFAVGAMNETICNIQEKTKWDLNEVKYIISHQANSRIIEYTAKKLNTEKDKFYMNLDKYGNTSAASIPIALDEMNKRGLLNKQDKIILVGFGGGLTFGGAAIVWSI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_CAMJJ
Sequence: MYYCISFTHKNTDIALREKLSFSNEAKKSEFLKIISTHENIEECLVISTCNRVEIVAFVKMACAEFIVKSLALLCDVDKDILLEKADIFEDSGAIHHLFSVASSLDSLVVGETQIAGQLKDAFAFAVKNNFCGVHLSRAVHSAFKCAAKVRNETQISKNSISVASVAVAKAKELADLTQKKAVVIGAGEMGELAAKHLIAAGAKVIILNRDLQKAKDLCERLGVLSEYDSLENLKKYLNQYEFFFSATNAPNAIITNSLVEELSYKRYFFDIAVPRDIDINENENISVFAVDDLEIVVQKNLALREQEARMAYGIIGRETSEFFRYLNDLALMPIIKAIRLQAKEYADKQLEIALKKGYLKKSDKEEARKLIHQVFKAFLHTPTVNLKHLQGKMQSDTVINAMRYVFDLQNNLEGLNQYKCEFDMENNDEIY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MALT_YERPS
Sequence: MLIPSKLSRPVRLQNTVVRDRLLVKLSSAANYRLTLINCPAGYGKTTLIAQWAADQSNLGWYSLDESDNQSERFATYLIAAIQLATGGHCSKSEALSQKHQYANLSALFSQLFIELSNWDGPLYLVIDDYHLITNDAIHEAMRFFLRHQPENLTLIILSRTLPSLGIANLRVRDQLLELGMQQLAFNHHEAQQFFECRLSSPLEQGDSSRLCDEVEGWVTALQLIALSSRQPNSSAQKSAKRLAGLNASHLSDYLVDEVLDQVDSKARAFLLRCSVLRSMNDALIVRLTGEDNGQQLLEELERQGLFIHRMDDSAEWFCFHPLFATFLRQRCQWELALELPELHHAAAEGWMALGYPAEAIHHALAAGDVGMLRDILLQHAWSLFHHSELALLEQCLTALPYPLLVQNPELALLQAWLAQSQHRYSEVNTLLEQAELAMQERKIPVDEILRAEFGALRAQVAINAGKPDEAEKLATDALKYLPMAHYYSRIVATSVTGEVHHCKGELARALPMMQQTEQMARRHEAYHYALWALLQQSEILIAQGFLQAAYETQEKAFELIREQHLEQLPMHEFLLRIRSQVLWSWSRLDEAEEAARKGVEILANYQPQQQLQCLAMLAKCSLARGDLDNANVYIQRCEALQHGSQYHLDWITNADKPRVIHWQMTGDKVAAASWLRQTEKPGMADNHFLQGQWRNIARVQIILGRFDEAEVVLDELNENARRLRLTSDLNRNLLLSNTLYWQTERKGEAQKALIESLTLANRTGFISHFVIEGEAMAQQLRQLIQLNALPELEQHRAQRILKDINQHHRHKFAHFDEIFVDKLLTHPQVPELIRTSPLTQREWQVLGLIYSGYSNDQIANELDVAATTIKTHIRNLYQKLGVAHRQEAVQQAQRLLQMMGYV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: CTAA_NITHX
Sequence: MTRPIVQKGFHLRAVRWWLVLMALLIAAMVLVGGATRLTESGLSIVEWKPVTGTLPPLSQEEWSQAFDGYKQIPQYSEMNAGMTLEQFKTIFWWEWSHRLLGRFIGVAFLLPFLWFMWRGMLPSDLKRRLWIIFGLGGLQGAVGWWMVASGLTKLVEVSQYRLATHLVLALLIFSAIVWTVRRLSDRPSLLSPMRLRVTSGILLVLVFVQLYFGALVAGLRAGKVFNTWPDIDGSFIPSSARLFFEQPWWRNLFDNTLTVQFEHRMMAYTLFAIAILHAIDAIVSRAGAAVVRGALWLAAAMTLQATLGILTLLHEVPILLALVHQGVAIIVLTLAVVQAERLMAGNAVRQRQGLGVAAG
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS3_LEPIC
Sequence: MGQKVNPIGLRIGITRGWDSIWFSQSDYKKNLHEDIKIRKFVQNRFNNAGVVKVVIERFPEKINVNLHTAKPGIVIGQKGANIEAVKKILKTMTDKPVNLNIIEVKKPETVAQCIAESIALQIEQRQPFRRVMKQELRRAMRGGVEGIKILISGRLNGADMARRENYKEGRIPLHTLRAKIDLGFKEAKTTFGQIGVKVWTYSGDFIQSKEESEEDKYAVKRRTS
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL13_BACC1
Sequence: MRTTFMAKANEVERKWYVVDAEGQTLGRLASEVASILRGKNKPTFTPHVDTGDHVIIINAEKIHLTGNKLNDKIYYRHTNHPGGLKQRTALEMRTNYPVQMLELAIKGMLPKGRLGRQVSKKLNVYAGAEHPHQAQKPEVYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: AGUA_THEMA
Sequence: MDYRMCWLEYRGLPADVAGKLKDWFSSVSILEPGSSVLKDEIRRFSERSIGITPRFYSRPLKKEKYIMVGRLESLPIKLDVNLGEEGFMLRTIEWNGSKILLVTGETKKALVYGIFDLMKRIRLGEDIEKMNVLAKPKAKFRMLNHWDNLDGTIERGYAGNSIFFKDNRIIINQRTKDYARLLASIGINGVVINNVNVKKREVYLIDSIYLKKLKKLADIFREYGIKIYLSINFASPVYLGGLDTADPLDERVARWWREKARGIYDYIPDFGGFLVKADSEFNPGPHMFGRTHAEGANMLARALAPFGGVVIWRAFVYNCLQDWRDYKTDRAKAAYDNFKPLDGQFDDNVIIQIKYGPMDFQVREPVNPLFGGMEKTNQILELQITQEYTGQQIHLCFLGTLWKEILEFDTFAKGEGSYVKRIVDGTLFDRENNGFAGVSNVGDSVNWTGHDLAQANLYAFGRLAWNPDEEIERIVEEWIKLTFGDDEKVLENVSYMLMKSHRTYEKYTTPFGLGWMVNPGHHYGPNPEGYEYSKWGTYHRANWEAIGVDRTSRGTGYTLQYHSPWKEIYDDINTCPEDLLLFFHRVRYDHRLKSGKTLLQTMYDLHFEGVEEVEEFIKKWEELKDRVSPDIFERVKERLHMQLEHAKEWRDVINTYFYRRTGIPDEKGRKIYP
What is the function of this protein?
Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  It catalyzes the cleavage of alpha-(1->2)-glycosidic bond of the 4-O-methyl-D-glucuronic acid side chain of xylan and releases 4-O-methylglucuronic acid from xylan.
What are the official names of this protein?
Xylan alpha-(1->2)-glucuronosidase, Alpha-glucuronidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 67 family.
Protein: SYN1_LACPL
Sequence: METISIINAADHVNEQVKIGVWLSNKRSSGKIAFLQLRDGTATFQGVALKNELGETAFAQLTDLAQETSLWVTGTIHADTRSPFGYELAISQFEVVGTSHDYPITPKDHGIDFLLDHRHLWLRSSRPNAIMRIRNEVIRAVYEFFNDRGFIKIDAPILTGSAPEGTTELFKTDYFGQDAYLSQSGQLYGEAGAMAFGKIFTFGPTFRAEKSKTRRHLTEFWQLEPEMAWMHQDESLEVQEQLVAYLGQAVIDHCPHELAVLDRDVATLQKYTKLPFPRVSYDDAITLLQANGFDVDWGVDFGSPEETFLAEHFDQPVFVLNYPKAIKAFYMQAHPTRDDVVIAADLLAPEGYGEIIGGSERSTDYDYLKERLLASGQDLQDYEWYLDLRKYGSVPHSGFGMGLERFLAWITLQDHVRETIPFPRMLHRIYP
What are the official names of this protein?
Asparagine--tRNA ligase 1, Asparaginyl-tRNA synthetase 1, AsnRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INVS_HUMAN
Sequence: MNKSENLLFAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHLTTRHRSPKCLALLLKFMAPGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAANHKDPSAVHTVRCILDAAPTESLLNWQDYEGRTPLHFAVADGNVTVVDVLTSYESCNITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPLHYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTALHAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHSLLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYALLGERHEVIQFMLEHGALSIAAIQDIAAFKIQAVYKGYKVRKAFRDRKNLLMKHEQLRKDAAAKKREEENKRKEAEQQKGRRSPDSCRPQALPCLPSTQDVPSRQSRAPSKQPPAGNVAQGPEPRDSRGSPGGSLGGALQKEQHVSSDLQGTNSRRPNETAREHSKGQSACVHFRPNEGSDGSRHPGVPSVEKSRGETAGDERCAKGKGFVKQPSCIRVAGPDEKGEDSRRAAASLPPHDSHWKPSRRHDTEPKAKCAPQKRRTQELRGGRCSPAGSSRPGSARGEAVHAGQNPPHHRTPRNKVTQAKLTGGLYSHLPQSTEELRSGARRLETSTLSEDFQVSKETDPAPGPLSGQSVNIDLLPVELRLQIIQRERRRKELFRKKNKAAAVIQRAWRSYQLRKHLSHLRHMKQLGAGDVDRWRQESTALLLQVWRKELELKFPQTTAVSKAPKSPSKGTSGTKSTKHSVLKQIYGCSHEGKIHHPTRSVKASSVLRLNSVSNLQCIHLLENSGRSKNFSYNLQSATQPKNKTKP
What is the function of this protein?
Required for normal renal development and establishment of left-right axis.  Probably acts as a molecular switch between different Wnt signaling pathways.  Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled (DVL1) for degradation by the ubiquitin-proteasome.  This suggests that it is required in renal development to oppose the repression of terminal differentiation of tubular epithelial cells by Wnt signaling.  Involved in the organization of apical junctions in kidney cells together with NPHP1, NPHP4 and RPGRIP1L/NPHP8 (By similarity).  Does not seem to be strictly required for ciliogenesis (By similarity).
What are the official names of this protein?
Inversin, Inversion of embryo turning homolog, Nephrocystin-2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Membrane; Peripheral membrane protein. Nucleus. Cell projection, cilium. Note=Associates with several components of the cytoskeleton including ciliary, random and polarized microtubules. During mitosis, it is recruited to mitotic spindle. Frequently membrane-associated, membrane localization is dependent upon cell-cell contacts and is redistributed when cell adhesion is disrupted after incubation of the cell monolayer with low-calcium/EGTA medium.
Protein: FYV6_KLULA
Sequence: MADNPKAPTFIKEGSGDLESQRRNEQVNREVGELVTRKSLSDQLRENSKKKRQQFQRQTKEKNSFTRVSNDDLDHINKVKLDELEKLRNFSQWAESEERNRRKQLQLLQQPSTPEHTNKQVISKNDPIPTSIKVRKLKTSNGAKNALGVISKPKHKKTDRTQKK
What is the function of this protein?
Involved in telomere length regulation and promotes fully efficient non-homologous end-joining (NHEJ) by a mechanism activated in postdiauxic/stationary phase.
What are the official names of this protein?
Protein FYV6.
What is the protein family that this protein belongs to?
Belongs to the FYV6 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: VERN_CLORO
Sequence: MTEHTVSHANGSDLENAKKTYMLANNQKEIERMKNQHEWIKGSFGGLVKAPIDFDKKNQSILDSATADGTWLMDVRSLFPPETELIGFDIAPELYPPEGTRPRNVELVTADLLQGLPAQWIGRFDLVHQRFVFPNFETEVIREVLGRLMQCVKPGGWIQLVEPCAGENVSGPEPKWFLLLHKLANQFMRSAVPRDAILAILHEEGFVNINIESLDIVIGKHQRNKEMDARGRRSMRDSVSNMYPMITAEQLGMPKEEARAVLDKFEADMQKYRTAVRHVIIWAQRPE
What is the function of this protein?
N-methyltransferase; part of the gene cluster that mediates the biosynthesis of 11'-deoxyverticillin A, one of the dimeric epipolythiodioxopiperazines (ETPs) from the verticillin family that act as mycotoxins (PubMed:28376389).  11'-deoxyverticillin A is required for normal conidiation (PubMed:28376389).  The nonribosomal peptide synthetase verP is speculated to be responsible for condensation of amino acids to form the carbon skeleton of verticillin, whereas the cluster-specific tailoring enzymes are involved in further modifications leading to the production of 11'-deoxyverticillin A (Probable).
What are the official names of this protein?
N-methyltransferase verN, Verticillin biosynthesis cluster protein N.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
Protein: MRAY_RHOP2
Sequence: MLYWLIDFSSSFPAFNVFRYITFRTGGAVVTGALFVFLCGPWIIDNLRLRQGKGQPIRADGPQSHLVTKRGTPTMGGLMILSGLTVGTVLWANPLNPYVWIVLAVTLGFGFVGFYDDYMKVTKQTHAGISGRTRLLIEFAIAGAACFALVWLGRGSLSSSLVIPFFKEVVLNLGWYFVIFGAFVIVGAGNAVNLTDGLDGLAIVPVMIAAASFGMISYLVGNAVFAEYLQINYVAGTGELAVLCGALLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAVIGGLFVLEAVSVIVQVASFKLTGKRVFRMAPIHHHFEQKGWTEPQIVIRFWIIAVILALAGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NU6M_DIDVI
Sequence: MKMMTIYIISLLLMIGFVAFASKPSPIYGGLSLVVSGGLGCGMVVSLEDVFLGLVVFLVYLGGMLVVFGYTTAMATEEYPETWVGNVVAFIMLLFVLLLQVGWYFMSKLVYIIMAIKLFDFVETSLVGQDYNGVSQLYYCGGWALALLGWILFMTIYVVLEVVRERSY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DNLJ_LAWIP
Sequence: MSINSPQYSLPSKKEKQRVRELRKFINHHNYLYYTLDDPEISDSEYDKAFQELLTLENTFPSLKTNNSPTQKVGNNILKKLEEQPHRQRMYSLDNVFSNDEWEGFLKRLANALPEVPFSFWCDPKMDGLALELIYEKGQLTSALTRGDGDIGEVVTEAVRTISNIPKRLKHSINAPELLEIRGEVVISRADFKKLNKEQEKKKKKLFANPRNAASGSVRQLDPTITASRPLRFLAYGIGEIQPSSLKWNTYHELMSYLKEYGFETPPKGKLCISSTEVQSYYTRLQAQRYSLRYEIDGIVMKLDDIQSQEKLGYTSRAPRFAIAWKFPATQVQTRLLQIHIQVGRTGVLTPVAELEPINVGGATISRATLHNEDEIKNKDIRPGDMVIVQRAGDVIPEIVSPILSDRSAKSKPFVFPKICPVCHEKVYRINNEVAWRCINLSCPAIRLQSIIYFVSKSGLNIQGIGQRLIELLVTSGCIKTPADLFTLTTADLLTYKRMGAKLAAKTIQALSLAKQTMSLHRLICALGIRHVGEQTARILASSFIDLDALSSASLEDLQQLSEIGPEVASSIQAFFKNKANIQMINQFREMNIWPIQQVNDTTTKGFFTGKKLLFTGTLERPRAEMKRLAEEAGAIVMTGISHKLDYVIAGKNPGSKLNKAQELHISILDEPTFLQKLLIVL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: REP_SALTY
Sequence: MRLNPGQQHAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKSNFSLFDDTDQVALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAGAKGERDRIFAHCYGLYDAHMKACNVLDFDDLILLPTLLLQRNDEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGQRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALQVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGPATLQKLGEWAMTRNKSLFTASFDMGLSQKLTGRGYDSLTRFTHWLGEIQRLAEREPVAAVRDLIHGIDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGNELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFPYVYMVGMEEGFLPHQSSIDEDNIEEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRAKS
What is the function of this protein?
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA.  It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
What are the official names of this protein?
ATP-dependent DNA helicase Rep, DNA 3'-5' helicase Rep.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: CAPSD_GLVWB
Sequence: MVWGTGYGNPSPLNPYGFASLHRGGLNPLILAPENITFDTLNTHNDHEETHGESPEVPKASIAPAGRQNVPVLQQNQENEDNHALGGSEDAKDEREIRFSAIKTLYNYYSEGPSTPIMPHLVNRLRGLDALAKIDATLTKVDMNAAYIFALRPTFPYSYGYKQRFSNRRLTTSALCYARTGLSSFLTVDKTYTSNSPLKGGSRGWPIFNVDVSSHVAEPHMRTLSPIGLEVFNLATSQFSKTLLTASSKVFTQSLYTADILSIFGEVFLPHVMQPVSNYTPILVRALLALIHILGPGSGNCSLSSSIFESSIPQFLTVSHSTNMSNRTRYCLHTRSAYKDMFRNGIPPQSTLPPTLAPEGSSARVLIPEALVTSPMFPWLLILVSSGPQFFLYSKDASINTVDIGSRGRITSPIPDVAKLDLHRLWNLFRFDGYRYIDVVIVGADRDYVWPYQNGVYVHGGKGPNGTGNYGNADVHDGIGTIFSSFNNNVNVQTSDLMLGLLTLWNHITTTYATEEEVTMAIKIAAAFALVYPVQPIVYSGCPKAFQRHTSYYQPSSENCYATDTAEVKSVWDTVELSVQVNNAMVLGMTLPFGQPTLSSAQWYNNIDKAEISMFKVGNLPLQNLDYLSLDMMEFYAPTTGQLYDIRSDNLILSAHRTVNLGIGYTALADFFAYLASVPAQSFYHDRMVTSPISKQTYSVYERFIERFIDDFVGWDRCDLFNLDTLLGAKHIAGVASSPIPWHCSLQRCPLPIIMHYTGLTFGQEHITVRDVAGVEGLQQIVMRDFQGRIVVERLGTAAPSRIAVKLDWSRLSAWYSDTTCAIPLSDRVMEIVNYAAIWDPTQERHAQVSCTHTLAPISFRALTCLSLYSIRVSTLHHLMTTRAKL
What is the function of this protein?
Binds and removes 5' cap structures from cellular mRNA.
What are the official names of this protein?
Major capsid protein, Gag protein, Major coat protein.
What is the protein family that this protein belongs to?
Belongs to the totivirus major capsid protein family.
What are the subcellular locations of this protein?
Virion.