PharMolix/UniProtQA huggingface dataset:
Protein: GPDA_LEGPH
Sequence: MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPENLIPSDNLIECVQSADYVIIAVPSHAFAEIINKIPKPTQGLAWLTKGVDPASHELLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGVGDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNKVEMPICEQINALLHGIVHAQEAVNNLMSRPAKEE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_SHESW
Sequence: MQNQRIRIRLKGFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERYTILISPHVNKDARDQYELRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: Y168_ADE02
Sequence: MSSATVSRTSRSKATGASSSSISSSIRASPSSSSSGGGGGGGTRRRRRRTGRRSTKRSIISPRRRRMVSVTARPFSRGRSWKTPPVMSRLWVGGGLPCGRDTALTMHLNNCCVGTPPPRDLSESASTGSENLSRKASNQSQSQGRLSTVAGGSGWRSGLFLAEVLLMM
What are the official names of this protein?
Uncharacterized protein C-168.
Protein: BGL44_ARATH
Sequence: MRHLSSPPWPLLLLLLLSSFTSGESSLSAEKNKLHTGGLSRQSFPKGFVFGTATSAYQVEGETHQDGRGPSIWDAFVKIPGKIAKNATAEITVDQYHRYKEDVDLMKKLNFDAYRFSISWSRIFPEGSGKVNWKGVAYYNRLIDYMVQKGITPYANLYHYDLPLALENKYKGLLGRQVVKDFADYAEFCYKTFGDRVKNWMTFNEPRVVAALGYDNGIFAPGRCSKAFGNCTEGNSATEPYIVTHHLILAHAAAVQRYRKYYQAKQKGRVGILLDFVWYEPLTRSKADNLAAQRARDFHIGWFIHPLVYGEYPKTMQNIVKERLPKFTEKEVKMVKGSIDFVGINQYTTYYMSEPHPTTKPKDLGYQQDWNVEFGFAKLGKPIGPRAYSSWLYNVPWGMYKALMYMKERYGNPTMILSENGMDDPGNVTLAQGLHDTTRIKYYKDYLTNLKKARDDGANVVGYFAWSLLDNFEWLSGYTSRFGIVYVDYKTLKRYPKMSAQWFKQLLKRNNK
What is the function of this protein?
Hydrolyzes p-nitrophenyl beta-D-glucoside, p-nitrophenyl beta-D-mannoside, cellobiose, 4-methylumbelliferyl-beta-D-glucoside, laminarin, amygdalin, esculin and gentiobiose.
What are the official names of this protein?
Beta-glucosidase 44, AtBGLU44.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPXK_XANCB
Sequence: MSKRGARTPGYWYDNTPIPLPARMLAPVYGAVTAVRRSLYRRGWLKRHGVPVPVVVIGNVTAGGTGKTPLTITLVSRLQQAGWTPGVASRGYGRDDAGTARWVDADTPVALGGDEPVLIAWKTGARVRVDTDRLAAARALVEAGCDIIVCDDGLQHYRLARDVEIEVVDGQRRYGNGRMLPAGPLREPAARARECDFRVVNLGQGSDAVIPAVATPVADTDAGFGEWQMRLSIDSVQPMDGKRARPLASLAGQRVHAVAGIAHPERFFAMLRARGIGVVPHAFPDHHVYRAQDFSFGSRLPVLMTEKDAVKCRPFADEWLYSVPLKAELPAAFWVSLLDRLDKLASRHSDA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: YACG_ERWT9
Sequence: MNDVTVVNCPTCNKQVIWDELSTWRPFCSKRCQLIDLGEWAAEEKRIPSSGDLNDSDDWSEQPLDRQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: NUOI2_NITOC
Sequence: MNTLRSYIKSFLLWELLLGLKLTGRYLFTKKVTVQFPEERTPQSPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITIDSEQREDGTRRTTRYDIDLFKCIYCGFCEESCPVDSIVETRILDYHFEERGEHILHKEQLLALGDKYEAQIAADRAADAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y132_RICCN
Sequence: MIEQDLIKVRIIGGNDSPESSKYLEDIRTTLNGIDNNTNMINIIGLDACKNIHPNSFELDGYHGGVRALDCRILN
What are the official names of this protein?
Uncharacterized protein RC0132.
Protein: Y25K_BNYVF
Sequence: MGDILGAVYDLGHRPYLARRTVYEDRLILSTNGNICRAINLLTHDNRTSLVYHNNTKRIRFRGLLCAYHRPYCGFRALCRVMLCSLPRLCDIPINGSRDFVADPTRLDSSVNELLVSTGLVIHYDRVHDVPIHTDGFEVVDFTTVFRGPGNFLLPNATNFPRPTTTDQVYMVCLVNTVDCVLRFESELTVWIHSGLYTGDVLDVDNNVIQAPDGVDDDD
What are the official names of this protein?
RNA-3 uncharacterized 24.7 kDa protein.
Protein: CCA_STRPG
Sequence: MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHDVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRIMRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEDLRKAQSLSVDMDRINTLDQALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREELAP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: ZBT12_HUMAN
Sequence: MASGVEVLRFQLPGHEAATLRNMNQLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRDQFLLNPSSELQVSLMHSARIVADLLLSCYTGALEFAVRDIVNYLTAASYLQMEHVVEKCRNALSQFIEPKIGLKEDGVSEASLVSSISATKSLLPPARTPKPAPKPPPPPPLPPPLLRPVKLEFPLDEDLELKAEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGLGGGLGIGGSVGGHLGELAQSSVPPSTVAPPQGVVKACYSLSEDAEGEGLLLIPGGRASVGATSGLVEAAAVAMAARGAGGSLGAGGSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHFIFMCPRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCDVRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger and BTB domain-containing protein 12, Protein G10.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPB_XYLF2
Sequence: MSDITVANYHAFPDARGHFGRYGGRFVAETLIGPLQELAQAYDAARHDPDFIAAYNKDLKDYVGRPSPIYHAERLSRKVGGAQILLKREDLNHTGAHKINNTIGQALLAARMGKTRIIAETGAGQHGVASATVAARLGLECVVYMGATDIQRQQINVYRMKLLGATVVPVTSGSATLKDALNEAMRDWVTHVGHTFYIIGTVAGPDPYPRMVRDFNAIVGREARAQMIEDYGRLPDAMTACVGGGSNAIGLFHAFLNDASVRIYGAEAAGDGIATGRHAASIVAGRPGVLHGNRTYVVCDDDGQILETHSVSAGLDYPGVGPEHAFLADSGRVQYVGIRDEEALAAFHLLAHTEGILAALESSHAVAHTMTLARDLPKDALVLCNLSGRGDKDVHTIAAREGVRV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SYC_CORDI
Sequence: MTLRIFDTGTRSLRDFEPIRPGHASIYLCGATPQTQPHIGHVRSGVAFDILRRWLIAQGLDVAFVRNVTDIDDKILTKAAENGRPWWEWVSTYEREFTWAYNQLGVLPPSVEPRATGHVTQMVEYMQRLIDNGFAYAAEGSVYFDVAAWTAAEGSDYGSLSGNRVEEMEQGETEITGKRGAHDFALWKAAKPGEPSWPTPWGDGRPGWHLECSAMATWYLGGEFDIHCGGLDLQFPHHENEIAQSHAAGDGFANYWMHNHWVTMSGEKMSKSLGNVLSVPNILDKVRPVELRYYLGSAHYRSMLEYSEGALLEAAAGYRRIEAFLTKVADVEAGQWTTEFEEAMNDDLAVPRALAEIHTQVRHGNSALAAGDVDKAHEIAASVRAMAAVLGVDPLDEKWLDSAASDSSTNAALDVLVQAELQRRTEARAAKDWATADEVRDRLHAAGITVTDTPDGPTWALNN
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_THEAC
Sequence: MHLIEKIYKNTREVVTREDAERLEGKSDIKSYIGIEPSGIPHIATAVMWPRKLAEIQDDIKVTVLLADWHAMINNKLHGDLDLIRKGGEILRKTFQAEGLTKADYVWASDLVDSSEYWRMFIDTAKRSTLKRVIRSLPIMGRNETDAEKDFSMYLYPIMQVTDIFYLDVDMAFGGMDQRHAHMLARDIAEKMKRKKVVSVHGFLLSSLKGNARMDNFVKMSKSDPNSAILVTDHMEDIERKINAAYCPPQQVEGNPVAEIMKYIIIPYYGKSIEIHGSNGVINLDSVENFDQAYQRGEIQPADLKHKVATILNEMVEPARRSLEGLDLSEFQ
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSBP_DROME
Sequence: MQHTRRMLNPLLTGLRNLPARGATTTTAAAPAKVEKTVNTVTILGRVGADPQLRGSQEHPVVTFSVATHTNYKYENGDWAQRTDWHRVVVFKPNLRDTVLEYLKKGQRTMVQGKITYGEITDQQGNQKTSTSIIADDVLFFRDANN
What is the function of this protein?
Binds preferentially and cooperatively to pyrimidine rich single-stranded DNA (ss-DNA) (PubMed:7673145, PubMed:8206370, PubMed:21953457).  Required to maintain the copy number of mitochondrial DNA (mtDNA) and plays crucial roles during mtDNA replication that stimulate activity of the gamma complex polymerase PolG1/tam at the replication fork (PubMed:21953457, PubMed:26446790, PubMed:14754882, PubMed:28318978, PubMed:7673145, PubMed:11294889).  Promotes PolG1 activity largely by organizing the template DNA and eliminating secondary structures to favor ss-DNA conformations that facilitate PolG1 activity (PubMed:26446790, PubMed:21953457, PubMed:7673145).
What are the official names of this protein?
Single-stranded DNA-binding protein, mitochondrial, Dm mtSSB, Mt-SSB, MtSSB, Protein low power.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL9_PROM0
Sequence: MAKRVQVALTESIASLGKEGDLVEVAPGYARNFLLPYGKAMNVTPAVLKQIERKKEKEKIAADKLKQEALDFQTALSTIGRFTIKKQVGEDGVLFGTVTNGDVAEAIEAATKKEIDRRNITVPDIHNLGSFTAKIKLHPEVNAEVNIEVTS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: PETG_CRYJA
Sequence: MIEVLLSGIVLGLIPITLAGLFVTAYLQYRRGDQLDI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RNZ_NOSS1
Sequence: MQITFLGTSSGVPTRARNVSSVALRLPQRAELWLFDCGEGTQHQILRSDLKVSQLSRIFITHLHGDHIFGLMGLLASCGLAGNVQRVDIYGPSGLNDYIQSASRYSHTHFSYPIKVHTVRPGVIYENDEFTVTCGLLHHRITAFGYRVAEKDRAGRFDIEKAKELQIPPGRIYGQLKRGETVTLEDGRVINGAELCGPTEIGRKMAYCTDTIYCDGAVELAQDADVLIHEATFAHQDSEMAFQRLHSTTTMAAQTALAAGVRRLLMTHFSPRYAPGNTIELKDLLQEARAIFPRTDMAYDFMTYEVPRRREPVFSSVSSSSV
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: MNME_LAWIP
Sequence: MCDTIAAIATPSGTGGIGIIRISGPKSKERLTELFHSVSPKFTDFKPWMLHRGYLVAPTNEFLDDILAVYMPAPYTFTGEDVVELHCHGGHFLLLTILETVLCKNIRLAKPGEFSQRAFLNGRMDLTQAEAVAELIAASSRNEVLLASNRLKGLLGQKIIDIRRRIEELRVWICLAVDFPEEESGIFPLEKFINGLLEIHEIIQKLIHAAERSRCWKEGVTVALAGAVNAGKSSLLNALLGKERAIVTEHPGTTRDFLEECIIVNSLSIRLIDTAGLRVTSDPIEEQGIQKGREKIDEADVILFIIDGTVGVTEESKLLINNFGVERTILVWNKVDLKVPPSNWTELYTSSQVSGICVSAKTGSGIEELLVLLYNFVLSQHNAQEPTFDTIVPNMRQVEVFSLVLEEIRSLYEDIRSGIPYDLCAVMLENISSMLNSIIGFDTPEEVLNRIFASFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_STRGN
Sequence: SIFDKLWERHVITGQEGQPQLMYVDQHYIHEVTSPQAFQGLRDAGRKVRRPDLTFGTFDHNVPTVNIYDIRDVISKAQIDKLSENVKDFGIEHAAHGSELQGIVHMVGPETGKTQPGKFIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTIWQVKPKKMLVKFTGVPPKGVYSKDFILALIARYGVAAGVGHVVEYAGDAIEHLTMEERMTICNMSIEFGSKMGIMNPDQKTYDYVQGRPGAPKDFEAAVADWKTLVSDPDAVYDKVIEIDVSQLAPMVTWGTNPSMGVEFGAAFPEIRDMNDERAYNYMDLSPGKKAEDIDLGYIFIGSCTNARLSDLQLAAKFVAGKHIAPNLTAIVVPGSRPVKRVAEKMGLDKIFMDAGFEWRDPGCSMCLGMNPDKVPDGVHCASTSNRNFEDRQGFGAKTHLCSPAMAAAAAIAGRFVDIRQLPEVQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SYH_LEGPL
Sequence: MVVDKIQAIRGMNDILPDSTSVWRFIEQTFINCLVRYGYKEIRFPIVENTQLFKRTIGEITDIVEKEMYTFNDLNGDSITLRPEGTAGCVRACIEHGLLHNQQQKLWYLGPMFRHERPQKGRYRQFNQFGVEALGITGTAIELELISICRRLWTDLGFSQSVQLQVNSLGEINERQKYRSILVEYLRDHFQILDEDSKRRLDKNPLRVLDSKNPDLQQLIQNAPKLIDVLGDDSREHFQSFCNGLETLGIPYSINPVLVRGLDYYGQTVFEWVTDQLGSQATICAGGRYDMLVEFLGGAPTPAVGFALGLERIFLLMETLNLLNESNNKQSIFIIATNEEAILKALVMAESIRNAHPSLDVITNTTGGGFKSQFKKADKSGARLALILGEDEIAREYVSIKDLRTEIEQISIPMTKINEFLQDYLA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_ANADE
Sequence: MSAAPTSGPLTCRRAGPLRGAIEVPGDKSISHRSLLFGALSTGETRVTGLLDAEDVHSTRKAVEALGAIVREEGGEVVVTPPATLREPGDVIDCGNSGTSLRLLTGVLSGVPGLSVLTGDASLRRRPVRRVIDPLRAMGANLSARDGDRLPPVVVRGGPLRGARQVLPVASAQVKSAILLAGLFAEGETTVVEPEKSRDHTERMLRGMGVPVKVSGLEVSVSAARPAGGRVDVPGDISSAAFFLCGAAALPGSEVTVRNLGVNETRTGLLDVLRAMGADVWLANLREVAGEPRADVTVRADRLEATEIRGATIPRLIDELPVVMVMATQARGRTVIRDAKELRVKESDRLAAMGETLARAGARIELYEDGCAIEGPTPLRGVEVRTRLDHRIAMSMAVAQLFCGGEPVVLDDVACVATSFPSFFRLLDQVAARVSVGGAP
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITIH1_BOVIN
Sequence: MGLRGLLCVCLVSLLALQAVAAQGSPTRNPKGGKKRMAVDAAVDGVVIRSLKVNCKVTSRFAHYIITSQVVNSADTAKEVSFNVEIPKTAFISDFAITADENAFTGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFSIHIIVGPRSKATFRLTYEEVLRRKLMQYDIVIKVKPQQLVQHFEIDVDIFEPQGIRKLDVEASFLPKELAAQLIKKSFSGKKGHVLFRPTVSQQQTCPTCSTTLLNGDFKVTYDVNRDDACDLLVANNYFAHFFAPQNLKKLNKNVVFVIDISSSMEGQKLKQTKEALHKILGDMRPGDYFDLVLFGSAVQSWKGSLVQASPANLEAARNFVQQFSLAGATNLNGGLLRGIEILNKAQQSLPELSNHASILIMLTDGEPTEGVMDRTQILKNVRDGIKGRFPLYNLGFGHDVDLNFLEVMSLENNGRVQRIYEDHDATQQLQGFYEQVANPLLRDVELLYPREAVSDLTQHRHKQYYEGSEIMVAGRIADHKLSSFKADVRAHGEGQEFMTTCLVDKEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKLEGQEKANVSAKALQMSLAYQFVTPLTSMTVRGMTDQDGLEPIIDKPLDDYLPLEMVGPRKTFMLQASQPAPTHSSLDIKKLPDQVTGVDTDPHFLIHVPQKEDTLCFNINEEPGVVLSLVQDPDTGFSVNGQLIGNEAGSPGKHEGTYFGRLGIANPATDFQLEVTPQNITLNPGSGGPVFSWRDQAFLRQNEVLVTINRKRNLVVSVEDGGTFEVVLHRVWRGSAVRQDFLGFYVLDSHRMSARTHGLLGQFFHPFDYKVSNLHPGSDPTKTDATMVVKNRRLTVTRGLQKDYRKDPRHGAEVTCWFIHNNGDGLIDGIHTDYIVPDIF
What is the function of this protein?
May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.
What are the official names of this protein?
Inter-alpha-trypsin inhibitor heavy chain H1, ITI heavy chain H1, ITI-HC1, Inter-alpha-inhibitor heavy chain 1.
What is the protein family that this protein belongs to?
Belongs to the ITIH family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTPX_BACVZ
Sequence: MAKRIFLFILTNLLVITTIGIVLTIITSVTGVGSYIQNGRIDLMALLVFSLVVGFVGSFISLGMSRWMAKTMMGVRVLNPKKQSLSYEEQQLVDRVHRLSRAAGMTKMPEVGIYHSPEVNAFATGPSKRRSLVAVSSGLLQQMDDAAVEGVLAHEVAHITNGDMVTMTLLQGIVNTFVVFLSRIAAWVASRFVKEDLAPVVHFIAMIVFQIIFSILGSLVVFAYSRHREFHADRGGADLAGKDKMIHALRTLKSYTGHVNEEDQTAVQTLKINGKKHSSLFSTHPDLDERIRRLEAK
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CD9_BOVIN
Sequence: MPVKGGTKCIKYLLFGFNFIFWLAGIAVLSVGLWLRFDSQTKSIFEQENNDSSFYTGVYILIGAGALMMLVGFLGCCGAVQESQCMLGLFFSFLLVIFAIEVAAAIWGYSHKEEVIKEVQKFYEDTYNKLKNKDEPQRETLKAIHIALDCCGLTGVPEQFLTDTCPPKNLIDSLKTRPCPEAIDEIFRSKFHIIGAVGIGIAVVMIFGMVFSMILCCAIRRNRDMV
What is the function of this protein?
Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (By similarity).  Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity).  In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity).  In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (By similarity).  Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity).  Acts as a receptor for PSG17 (By similarity).  Involved in platelet activation and aggregation (By similarity).  Regulates paranodal junction formation (By similarity).  Involved in cell adhesion, cell motility and tumor metastasis (By similarity).
What are the official names of this protein?
CD9 antigen.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Secreted, extracellular exosome. Note=Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO.
Protein: COX16_CANAL
Sequence: MSYSGNRVFRGKKEQEAYDKTLAGRYVKLVKKNHFLFFGLPFLVSIVAGSIYLQKFTSVKWEKYDEKYQQLGEEEMLNLIENKRTVDKKNDYYRLQGLLNDHTNQVADDYEIVRVQRRKEDEPVWDRQ
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  May participate in merging the COX1 and COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: CTR1_SOLIN
Sequence: IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNYLSESGDVYDVEDAVVNKNYDDFLLRNDVALVHLTNPIKFNDLVQPIKLSTNDEDLESNPCTLTGWGSTRLGGNTPNALQEIELIVHPQKQCERDQWRVIDSHICTLTKRGEGACHGDSGGPLVANGAQIGIVSFGSPCALGEPDVYTRVSSFVSWINANLKK
What are the official names of this protein?
Chymotrypsin-1, Chymotrypsin I, Soli C1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ARPC2_PONAB
Sequence: MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTFSSR
What is the function of this protein?
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  Seems to contact the mother actin filament.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 2, Arp2/3 complex 34 kDa subunit, p34-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Synapse, synaptosome. Nucleus.
Protein: TSPO_MOUSE
Sequence: MPESWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIVWKELGGFTEDAMVPLGLYTGQLALNWAWPPIFFGARQMGWALADLLLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATVLNYYVWRDNSGRRGGSRLPE
What is the function of this protein?
Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity).  Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides.  Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:9832438, PubMed:24814875), but its precise physiological role is controversial.  According to some reports, it is not required for steroid hormone biosynthesis (PubMed:24174323, PubMed:24936060).
What are the official names of this protein?
Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR.
What is the protein family that this protein belongs to?
Belongs to the TspO/BZRP family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein.