PharMolix/UniProtQA huggingface dataset:
Protein: SYP_BURVG
Sequence: MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPIGLRSIRKVEAIVREEMNRAGALELLMPAVQPAELWQESGRWEQYGPELLRFKDRKDNDFVIGPTHEEVITDIARNQIKSYRQMPVNFYQIQTKFRDEIRPRFGVMRGREFLMKDAYSFDKDAAGLNESYRKMYDAYVRIFTRLGLEFRAVAADSGSIGGNFSHEFHVIADTGEDAIAYCPTSEFAANIEAAEALPLIAERAAPAQAMEKVATPGKAKCEAVAELLAIPLERTIKSIVLATDNEGAEPTIWLVMLRGDHDLNEIKVSKLPGLKNHRFATEQEIVEWFGTPPGYLGPVGTKKPVKVIADRTVANMSDFVVGANEVDYHIAGVNWGRDLPEPDVADVRNVKKGDPSPDGKGVIDICRGIEVGHVFQLGTKYSEAMGATFLDESGKPQPMLMGCYGVGVTRILGAAIEQNFDDKGIIWPESIAPFELVLCPMGYDRSEMVREAADKLYAELTAAGVDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKDGKVEYQGRRDAEATLLPADAAAATVTEKIRAALAH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHE_MAIZE
Sequence: MATAATATAGSRAAVLLLLSLALALALRPSDAGAGGDCHFPAVFNFGDSNSDTGGLSSLFGAAPPPNGRTFFGMPAGRYCDGRLVIDFIAESLGLTHLSAYLNSIGSNFTQGANFATAGSSIRRQNTSLFLSGFSPISLDVQFWEFEQFINRSQLVYNNKGGIYREILPRAEYFSQALYTFDIGQNDITSSYFVNNTTEEVEAIIPDLMERLTSIIQSVYSRGGRYFWIHNTGPLGCLPYALLHRPDLAIPADGTGCSVTYNKVAQLFNLRLKETVASLRKTHPDAAFTYVDVYTAKYKLISQANKLGFDDPLLTCCGYGGGRYNLDLSVGCGGKKQVNGTSVVVGKSCENPSKRVSWDGVHFTEAANKFVFDQIVAGALSDPPVALRQACHSRGQ
What is the function of this protein?
Esterase that can hydrolyze acetylthiocholine and propionylthiocholine in vitro (PubMed:15980188).  Substrate preference is propionylthiocholine > acetylthiocholine (PubMed:15980188).  Possesses extremely low activity against butyrylthiocholine (PubMed:15980188).
What are the official names of this protein?
GDSL esterase/lipase ACHE, Acetylcholinesterase, AChE.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZAPA_HAEDU
Sequence: MSANYIEVQIFGQVLRLHCPAEQQENLRASAQRLEERVALLKDQSGIIQLEKVLAIVALNLNYELEQEKQKNADNKTVLESCIHQLDSSLNKLATTGSIAINQENI
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division (By similarity).
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid- cell.
Protein: HDA21_DICDI
Sequence: MSTIHQVNEMNSRVGEKPACCIGAARGHCTAHCPRIEDVLYSQRKGKTNKGAQRWRCKACGTKWTSKGIIIQPPVVPDTIVNSIGFGNGPEEISMEQLRANARPYKKTKTGDNILQTSPFPSLFGNSIGMGLGGNNNNINNNNNSNGSNSSNNSHNGGSSPSGSPIPSPPSPVSFLQRNSNVFVPILPQSNGNNINNNNNNNSNSNSNNINSNSSNSMQLQNNNNNNGQLRSSSSSLSLSSSSSQLNSSSNGNGSSRNLLTSQKSAQSLIGNINNNNNNNNIINNNSNNNTNNNNNIMNGTTTSTTKPVVVGGPMQILNSVVNNSPTSSKPILSSSSQNLLYNSSGSIPQPSQSPQNNNNTTINNNNNTTNNNNNNNNSNNNNNSNNNNNNSNNNNINNVANGTPRPSLQTSRLQGKLPSPQQYNTSPSHQQYPSPKNNNNSNNIIPIQSTYGQPTPPPTKPPVSSKAPAVYHNVRVPSPNTTVDNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNSNNNNNNINNNNNNNNNSNNNNNGNSNNNNNNNSNYQQQHQYFSPNQNYIQQQVQAVQTQQAQHILAQQQAQAQQQYIQQLQLQQQTLAHAQSQAAHQAQTLTHSRHNDLLSPIDSQIWAPIQYSWIQTHYNPSSSLLECLKRLINSVVVFSNELPVDQRLKMINFLTTLSSPSSESQYNTNASKQMLNCIDNSVFNITKHYQMLYQSISKHYSMMEDSFIPLTEVYFDENEINKFIHFSDQFKIIEEQFEFILRELSSIRDTLIIKRENIEKNIIESSKFLNNSSNNDNGIEEIGLEQAKQDTTRLLESLAPLETTLNSMEIKFKSIQKEISMVIRVFSFFELLYNIHINCHQTIVEKHSRQLSTYMIDVIQQSLYNCDVISVAYNRLKTGLFNSNNNNNNNNNNNNNNNEEDDQLIDTTNPFINKLSDLLSKYENISKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNRNRDRDREFERDNNSNNNNNNIEKERNRNNRIRDRDNMDIDNISSFISNNQQQHIGQSQSVQQSSQLPKERKVMALYHTTCLDHLVPDDHPESPKRLSSVIKAINDFSRQSDRLIIKNDPEEINDKWILTVHSPEYLRLLEDLTEKLDANEIRPLNVNNDGASTGINQFSTSTPITTTGTATVTPGSTTSSTNGEQCEDGDTFVSKLSLHAAKRSAGATCQAIDNVMKGNVTSAFVAARPPGHHAGRDGLTSGTSSQGFCLLNHVCIGAKYAQLKYNLDKIAIIDFDVHHGNGTEEILSNDQGFYFLSIHMFEEGFYPGSGGGVGSIGVVNLNEFNEQNDYDDDDNNNDVNNNNNNNNNNNNNNNNNNNNKNNNNNNSNSITQQSTITNNSNCKGNIVNIPLDPKSSASSFLKAFSIIIDKLNDYQPELILISCGFDAHMEDHLASLCLLEENYVEITRSLRRVADRWCKGRLVSILEGGYNINALRQCTIAHLSALSEDD
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
What are the official names of this protein?
Type-2 histone deacetylase 1, DdHdaD.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: GNAI3_XENLA
Sequence: REAAERSKMIDRNLREDGEKASKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYKVVVYSNTIQSIIAIIRAMGRLRIDFGDVARADDARQLFVLASSAEEGVMSPELAGVIQRLWEDSGVQACFSRSREYQLNDSASYYLSDIERIAQGSYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLLLAEDEEMNRMHESMKLFDSICNNKWFIDTSIILFLNKKDLFEEKISRSPLTICYPEYSGSNTYEEAAAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKSNLMECGLY
What is the function of this protein?
Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades.  The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state.  Signaling by an activated GPCR promotes GDP release and GTP binding.  The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal.  Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins.  Signaling is mediated via effector proteins, such as adenylate cyclase.  Inhibits adenylate cyclase activity, leading to decreased intracellular cAMP levels.  Stimulates the activity of receptor-regulated K(+) channels.  May play a role in cell division.
What are the official names of this protein?
Guanine nucleotide-binding protein G(i) subunit alpha-3, G(i) alpha-3.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Membrane; Lipid-anchor. Note=Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody.
Protein: NAGZ_METFK
Sequence: MTLGPIMLDVVGTELTQEDIRRIRHPLVGGVILFARNFESPAQLKALTDSIHAVRQPPLLIAVDHEGGRVQRFREGFTRIPPMREFGKIWDEHPRKARQLAEEAGWIIAAELRAHGIDFSFTPVLDMDYGESQVIGDRAFHGDRQAINELAFSLMQGLKRGGMAAVGKHFPGHGYVVADSHVAIPVDERDFDQIASTDMQTFRQLIDDGIQAIMPAHVIYPKVDNKPAGFSERWLQKVLRQRLGFNGVIFSDDLSMEGAGVVGDVTQRALAALNAGCDMVLLCNQPDKADELLANLKWDIQAQSLARLARMHGGRHPSSMVALHEDPDFMHAVHRVGQVGKADGDLPFA
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCC2_ORYSJ
Sequence: MERGGFGGAGRHDEEAPAMRPAPQQRYRTVESHDRAVVQMAPMEFGSSADASASAGPRYIKPGTNLRTDARMHMASSNGRSSNGSQGDSKLELFGFDSLVNILGLKRMVGEQAQASASTRDGENAGIAIGHPKETETKLDTMMGVFVPCLQNILGIIYYIRFTWIVGMGGVWQSLVLVAFCGSCTFLTTISLSAIATNGAMKGGGPYYLIGRALGPEVGVSIGLCFFLGNAVAGAMYVLGAVETFLDAVPSAEFFQESVTVVTNTFVNGTAAGNATTISTPNLHDLQVYGIIVTILLCFIVFGGVKIINKVAPAFLIPVLFSILCIYIGVFIAPRPNASKWITGLSITTLKDNWSSDYQRTNNAGVPDPNGSIYWDFNALLGLYFPAVTGIMAGSNRSASLKDTQRSIPIGTLHATISTTMMYLLSVFLFGALSTREGLLTDRLLCAAVAWPSPAVVYAGIILSTLGAALQSLTGAPRLLAAIANDDILPVLNYFKAYEGSEPHVATLFTSFICISCVIIGNLDVITPTITMFFLLCYAGVNLSCFLLDLLDAPSWRPRWKLHHWSLSLIGALLCIVIMFMISWTFTVVSLALASLIYYYVSLKGKAGDWGDGFKSAYFQLALRSLRSMGANQVHPKNWYPIPLIFCRPWGKLPEDVPCHPKLADFANCMKKKGRGMSIFVSIIDGDYHESAEDAKTACRQLSAYIDYRRCEGVAEIIVAPSTSIGFRSIVQTMGLGNLKPNIVVMRYPEIWRRENLTQIPSTFVSIINDCITANKAVVIVKGLDEWPNEYQRQYGTIDLYWIVRDGGLMLLLSQLLLTKESFESCKIQVFCIAEEDTEAEELKADVKKFLYDLRMQADVIVVTVKSWEADPDRSGGSKKDDPEVYRSAQSRIRTYISQLKEAAERERRPLMEGGKQVVVDEQKVEKFLYTMLKLNATILRHSRMAVVVLVSLPPPPLNHLAYCYMEYMDLLVENIPRILIVRGYRRDVVTLFT
What is the function of this protein?
Probable cation/chloride cotransporter.
What are the official names of this protein?
Cation-chloride cotransporter 2, OsCCC2, Potassium-chloride cotransporter 2.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSIE_YERPS
Sequence: MAKNSRSQWIAKNLQRLLNVGLIMLAAILVVFLVKETIHLGKVLFLSNQETSSYMLIEGIVIYFLYFEFIALIVKYFESGYHFPLRYFIYIGITAIIRLIIVDHENPIDTLIYSGSILVLVVTLYLANTERLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADRB1_SHEEP
Sequence: MGAGALALGASEPCNLSFAAPVPDGAATAARLLVPXSPLRLAADLGQRGTPLLSQQWTVGMGLLMAFIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLTRARARALVCTVWAISALVSFLPIFMQWWGDKDAKASRCYNDPECCDFIINEGYAITSSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLSGPARLPSPALSPGAPLPAAAVANGRANKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKAFHRDLVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKAFQRLLCCARRAACGSHGAAGDPPRAAGCLAVARPSPSPGAASDDDDDDDEDDVGAAPPVRLLQPWAGYNGGAAANSDSSPDEPSRPGCGSESKV
What is the function of this protein?
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins.  This receptor binds epinephrine and norepinephrine with approximately equal affinity.  Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity).  Involved in the regulation of sleep/wake behaviors (By similarity).
What are the official names of this protein?
Beta-1 adrenergic receptor, Beta-1 adrenoreceptor, BETA1AR, Beta-1 adrenoceptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Colocalizes with RAPGEF2 at the plasma membrane. Found in the Golgi upon GOPC overexpression (By similarity).
Protein: YD019_HUMAN
Sequence: MRIFRGCTQPSTLGQGVHSPLMKAQFITHHSRKQVKPGEGWGRSSFTRACRDHTTILSGNRSFSAVAATPAKHKHMHTRTHTHMHTHTGMHTLTGTHVHTPHTQMHTRILTLSHMHTHAHTHAHTHGHTHTRAHSTHAHTHAHSHYHTRTLTLTHSHAHSCTLTSTITHMHTHTHMHTHTSTLTRTLTLTHTHMHTFLSLVSHLAGYISCQFIFSSENPRLCH
What are the official names of this protein?
Putative uncharacterized protein FLJ46204.
Protein: SDC1_ORYSJ
Sequence: MVGSVGNGLVDLGGAAVAVNGVGKGMRPEAVAVAMEVESPPRPAEEEGEGSPTRREIVLGRNVHTASFAVKEPDADDEETGEREAAMASVLALYRRNLVERTKHHLGYPYNLDFDYGALGQLQHFSINNLGDPFIESNYGVHSRQFEVGVLDWFARIWELEKNEYWGYITNCGTEGNLHGILVGREVFPDGILYASRESHYSVFKAARMYRMDCVKVDTLISGEIDCEDFQRKLLLNRDKPAIINVNIGTTVKGAVDDLDLVIKTLEEGGFKDRFYIHCDGALFGLMIPFVKKAPKVSFKKPIGSVSVSGHKFVGCPMPCGVQITRLEHINRLSSNVEYLASRDATIMGSRNGHAPIFLWYTLNRKGYRGFQKEVQKCLRNAHYLKDRLKEAGIGAMLNELSSTVVFERPKDEEFVRRWQLACEGNIAHVVVMPSVTIDKLDYFLNELTEKRATWYQDGSCQPPCLAKDVGEENCLCSIHKK
What is the function of this protein?
Catalyzes the biosynthesis of ethanolamine from serine.  Decarboxylation of free serine is the major source of ethanolamine production in plants and ethanolamine metabolism is crucial for the synthesis of choline, phosphatidylethanolamine (PE) and phosphatidylcholine (PC), and thus for plant growth (By similarity).
What are the official names of this protein?
Serine decarboxylase 1.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: TM131_DROME
Sequence: MPTQVQMRPLLRIFAEPILLILIFLFTLGAKGEKVLQETFLGLQEAPIHDLGDLRLVPSRLDFGTWSVGQARSQTVTLFNQHSNRTLQLNAVAGPSPAFYSSFLGTREVPPQGNTTFNVVFLPRQLGAIAADLLIHTSFGQAELAVQGEGSECPYRLKPLVGIKAPMNATLTPEIHMYNPHERPLQILEIYSSGGEFQLELPSGGSEGPQNLWKIPPHTLKPVIRISFHGRTAGNHSAYIRIKVAEQELDIFIPVEFEILPRHSVYARNPLADFGRVATLNAPDALQFKLDVRNDESRQLFGSYLRQIPGLSFDANNTSIVLDASLFEGDEIINDLLVINSNQSSTSPGADQPFTVLVRAEIFHGGLTFDRNATRFVTTSPEGVEGEPLERKRSLVVRNKFAIPLMLFNVSLTEPIDESILEVTLVGDPRILIQPDESVELLRLNLLNDQVPFKSFLRIETNVTVFKLPLVSCSGRLHVSTQPIVLNFRQESLEKAAYNLELDLGTVPFAEMSRDGFVILRNDNPVPVRITNWFFKHPKTVYSQSTFLGCRATAIGHPVSVENDTKGWHLCTEIRAGESAVFKVAIQTYEADATFGTLKVWTPYEVIRVRVKFEASVGHLEIDQEQLSFKNCFPGKMCTAVLSIRSSFTHPVHVKGISFALPVGLRFKDFNAKGTTIAPQTLTKVGRIYFDPASVCRNNCYIRESTNDLAIFPSVPGGGNGNSGVINNNLLYDGVELRQRTELFRQLRRQLSSMSLTLHSEELPPLELDFSITIEWPKLVQFQPIPPTPAIEVGQVQRQWITLTNPSQSPLLLDYFLSDPAFARRTQLSLPHEVIDVSSTSCYLTDKEVFSLPEAGDPILLPGGASLTIPITFSAQLPEKYCTLLHVRSNLTLYEAVWLQARAVQSQFRFGNRRPGAASPLLFEMATNQFQGCQSGNEAVVVTRSFTARNSGVIPIRIEGFLIGSLPCEDFGFKVMDCAGFDLGENEARKVEIAFSADFTTSAVKRSLTLLTNLTYDISYKLLAQMPAESVELCASLLVRPGWESSLKNAALVVLLASFGLVLVAAVFDAKAIMVQQNAYDAARNKGPLQPTFNLRNIVKLQAEEAAAKAESVQQQQKVKNGQLKELRKRTVVNSTNSKSKSKSSWSPWSMDMNALSKHLQKAKPKTVVSTPVTPPAASAPAAAPVPLPEAKPVKKSSTPSPQGVPISVQVRPQKKVKPTPAVVLGTTKPKQEVSTPVADQHEKSLAKSSPPQQENISPKPNKPPEQRVLKEQNGSAKKMGKTPGRERERERRSKDQKLTNGTGAGVGFRKPERKQRQKLNFGQTTNSTSPPESPDALKCISNPWETSSRVSFRDVLRTPQMAPTDNGFDWNHATSSSDLGPIGDNRKNATPPMVTSLWEPLSATASNSLFANTEVDFITPDAIYEQREREKPQWEQRSDLVMRQQLLLQQPQKLEFQLRQQEKISLLANMDPSNWATNWSPLGYSTWPNATAGIGVMRPPPGLEQSARQTHNLAQEQVSAGPASGTGAALHGESLPTQYDPFTSPSSIWSDTWRQSSQRNNHNHMN
What are the official names of this protein?
Transmembrane protein 131 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM131 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SCOC_BRUMA
Sequence: MVEINCFRLMSTDTTVTNETDNFPLVDDESQGSSIDTGGRIPRPAQPLPRDESDDQEEKARLISQVLELQNTLDDLSQRVDSVKEESLKLRSENQVLGQYIQNLMASSAVFQPAQSKAPQTK
What is the function of this protein?
Positive regulator of amino acid starvation-induced autophagy.
What are the official names of this protein?
Short coiled-coil protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SCOC family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network. Cytoplasm, cytosol.
Protein: NIT1_RAT
Sequence: MLGFITRPPHQLLSLLCTGYRLPQISVLCTQPRPRAMAESSSTSWELPLVAVCQVTSTPNKQENFKTCAELVQEATRLGACLAFLPEAFDFIARNPAETLLLSEPLDGDLLGQYSQLARECGIWLSLGGFHERGQDWEQTQKIYNCHVLLNSKGSVVASYRKTHLCDVEIPGQGPMRESNYTMPGYALEPPVKTPAGKVGLAICYDMRFPELSLKLAQAGAEILTYPSAFGSVTGPAHWEVLLRARAIESQCYVIAAAQCGRHHETRASYGHSMVVDPWGTVVASCSEGPGLCLARIDLHFLQQMRQHLPVFQHRRPDLYGSLLPLS
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione.  Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors.  Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT.  It is also a negative regulator of primary T-cells.
What are the official names of this protein?
Deaminated glutathione amidase, dGSH amidase, Nitrilase homolog 1.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
What are the subcellular locations of this protein?
[Isoform 1]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm.
Protein: SYGA_BREBN
Sequence: MTFQDIILTLQNFWAKQNCLIVQPYDVEKGAGTLNPMTFLRSIGPEPWNVAYVEPSRRPADGRYGENPNRLYQHHQFQVIMKPSPDNIQELYLESLRELGIEPLEHDIRFVEDNWEHPGLGAWGLGWEVWLDGMEITQFTYFQQVGGLECKPVAVELTYGLERLASYIQEKENVFDLEWCNGYTYGDVFLQPEYEHSKYTFELSDVDMLFSLYNTYEAEAKRLMAERLVYPAYDYVLKCSHTFNLLDARGAISVTERTGYIARVRNLSREVAQTYYKERERLGFPLLQKGNADAADQVNQVKGEDTNE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH602_POLNA
Sequence: MAAKDVIFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQMVKEVASKTSDIAGDGTTTATVLAQAIVHEGMKYVAAGMNPMDLKRGIDKAVHALVEELKKASKATTTSKEIAQVGSISANSDETIGKIIADAMDKVGKEGVITVEDGKSLESELDVVEGMQFDRGYLSPYFINNPEKQSALLDNPFVLLYDKKISNIRDLLPTLEQVAKAGRPLLIIAEEVEGEALATLVVNTLRGILKVVAVKAPGFGDRRKAMLEDIAVLTGGKVIAEEVGMSLEKVTLADLGQAKRIEVGKENTIIIDGSGEAADIEARVKQVRVQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALLRAKQTAGVIKGDNADQDAGIKLVLRAIEAPLREIVYNAGGEASVVVNAVLAGTGNYGFNAANDTYGDMIEMGILDPTKVTRTALQNAASVASLMLTTECMVCESAKDDAPAGGMGGGMGGMGGMGDMGM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAN8_MOUSE
Sequence: MAALAAGISKQRAAAQGLGSNQNAVKYLGQDFETLRKQCLNSGVLFKDPEFPACPSALGYRDLGPGSAETQGIIWKRPTELCSNPQFIVGGATRTDIRQGGLGDCWLLAAIASLTLNEKLLYRVVPRDQSFQKNYAGIFHFQFWQYGEWVEVVIDDRLPTKNGQLLFLHSEEGNEFWSALLEKAYAKLNGSYEALAGGSTIEGFEDFTGGISEFYDLRKPPGNLYYTIQKALRKGSLLGCSIDVSNAAEAEATTRQKLVKGHAYSVTGVEEVDFRGLPEKLIRLRNPWGEVEWTGAWSDSAPEWNYIDPQKKGELDKRAEDGEFWMSFSDFLKQFSRLEICNLSPDSLSSEEIHKWNLVLFNGRWTRGSTAGGCQNYPATYWTNPQFKIHLDEVDEDQEEGTSEPCCTVLLGLMQKNRRRQRRIGQGMLSIGYAVYQIPKELENHTDEHLGRDFFQGRQPSTCSSTYMNLREVSSRVQLPPGQYLVVPSTFEPFKDGDFCLRVFSEKKAQALEIGDAVPGDPHEPHPRDMDGEDEHFWSLSEEFADKDSEISAHQLKRVLNGLLSKRTDMKFDGFNINTCREMISLLDGDGTGSLRPVEFKTLWLKICKYLEIYQEMDHSRAGTIDAHEMRTALKKAGFTLNNQVQQTIATRYACSKLGVDFDGFVACMIRLEILFKLFRLLDKDQNGIVQLSLAEWLCRALV
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease (By similarity).  Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein.  Proteolytically cleaves the beta-subunit of coatomer complex.
What are the official names of this protein?
Calpain-8, New calpain 2, nCL-2, Stomach-specific M-type calpain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus.
Protein: TUL1_YEAST
Sequence: MEIDGNTLVFIIVILFLFFSSPGGDGVSSQYEFNQLQRLKQQFRTEHNTFVNMTYTDSFRNITGLKLSYQDMLNNPLQNATYPLPGKDYDRWFPNQNYMVLPNDVIEAINTEVWNTSNDDASNLFPPNITSTLLGKIDLVSNNKYEKIRMPVPRFYEPATDFSEDIPPEGETYWSEWPSYGELHNVSFQHGEIAIQISHMSNLQDNNNYLRRNFINKKNDRWKLLNLQIDFSDKAEKEKHSIYSKAVYDIQRGRILSISQSSKFHSLFALPHYMSFQNDYNEKIFNDVKELVDEFWNFTDYTDVMTMKDVQDAYNNANFKCEYLIFLQLEPWNQYTRDQIKLIDDELNWPLGRPANLSSLPPINVVSGLLYSPDCGVRLGLHNVKGTRYELKIMSIRKHLLFGIALFAAQIYLLLTQMHHTNTPSMVNKISFYCFSMINLVDGSLATLYFVAASVVPELYLPLVISAFSCFILASIFEIRYLISIYASQVNEQNVGIINLLRGNTGTYDENRPRPAFIPDEGSIGGSLYGRFFFMLIIFTFLILSSTSWPRQLRMVFEYILIFILNSYWIPQIFRNAVKGIPSRRERARSSIGGNRSQNKMPLLWSFVIGTTIIRSLPVVYVFTYSSNVFRHHKDVHFVVFLSLWLLFQISILYSQDVLGSRWFLPKHTIPDGYSYFKPLSNEYISEHGGGTAEHTVDCAICMSDVPIYIEEIPETHKVDQHSYMVTPCNHVFHTSCLENWMNYKLQCPVCRSPLPPL
What is the function of this protein?
Catalytic component of the DSC E3 ubiquitin ligase complexes that tag proteins present in Golgi, endosome and vacuole membranes and function in protein homeostasis under non-stress conditions and support a role in protein quality control (PubMed:25078903, PubMed:29355480).  Mediates ubiquitination of vacuolar proteins such as CPS1, PPN1, PEP12 and other proteins containing exposed hydrophilic residues within their transmembrane domains, leading to their sorting into internal vesicles in late endosomes (PubMed:11788821).  Targets also the unpalmitoylated endosomal SNARE TLG1 to the MVB pathway (PubMed:15973437).
What are the official names of this protein?
Transmembrane E3 ubiquitin-protein ligase 1, RING-type E3 ubiquitin transferase TUL1.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: HIS82_LEGPL
Sequence: MSIDFQQLPHAGIRSLIPYVPGKSIEELAKEKGITDIIKLASNENPLGCSPLALSAIQTMSSHYIATYPSPWNHPLMSKLASYLKVKPEQLFLSNGSDYLFNILLNCFALHTDRHILTHDYAFSTYAIQANSLQIPINSVPIGHNWEVNITDIVNACNQKTGIIFIANPNNPTGVLIQQEEIKYLLEQIPKSTLLVLDEAYYEFAASQLTVNSLDWLEEHPNLVVTRTFSKIYGMAGLRLGYAIANPSIINILKRVQLPFIVNQVALAAAYAAIDDDDFIQSSLKMNNEGMSQLQAGFNELNIKYLPSSCNFLTFDCEEDSMALYNYLLDNGIIVRPLHAYKMNNFIRVTIGTKEQNSRFLTALKNFYL
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RS2_CORGB
Sequence: MAVVTMRELLDAGVHFGHQTRRWNPKMRRFIFTERNGIYIIDLQQTLTYIDQAFEFVKETVAHGGTVLFVGTKKQAQEAVQVEADRVGMPYVNHRWLGGMLTNFQTVSKRLNRMKELQAMDAAENGYEGRTKREVLMLTRERTKLERVLGGIAEMTRVPSALWIIDTNKEHIAVAEAHKLNIPVVAILDTNCDPDVVDFPVPGNDDAIRSTALLSRVISTAVEEGKKAREERQLAAAKDAAGDAKPEAEEAPVAAEAEEAPAAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: GSH1_SALAR
Sequence: MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIQHMLTFMRDLHRYTARKLGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVTEGDAAKEKISAGYFRLIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEKTDCGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYVQIGLEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCVLADAPEMSSSELLCTRANWNRVILEGRKPGLTLGIGCETAQFPLPKVGKDLFRDLRRVAQTLDSIHGGEDYQKVCDELVACFDNPELTFSARILRSMIDTGIGGTGKAFGEAYRNLLREEPLEILQEEEFIAERDASVRRQQEIEAADTEPFAAWLAKHD
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: UP355_STAAR
Sequence: MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDKMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVGVRDHSSHQEVLENNSAYEEVDITHFAEASKGPKA
What are the official names of this protein?
UPF0355 protein MRSA252.
What is the protein family that this protein belongs to?
Belongs to the UPF0355 family.
Protein: YDZQ_BACSU
Sequence: MKSIDLTILSLKRKGIRTEKVLKNQNPDRLSHMTDKNAQPKSKEKEE
What are the official names of this protein?
Uncharacterized protein YdzQ.