PharMolix/UniProtQA huggingface dataset:
Protein: RDGC_ECO8A
Sequence: MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGSLPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: QUEF_GLAP5
Sequence: MNYNNECLSMLKLGKKTEYKSTYDPSLLQAVPRYLNRESLGIVKQQPFTVGADIWTLYELSWLNQNGVPQVAIADVIIDSSSSNIIESKSFKLYLNSFNQMRFPSREDVQRRIQSDLSKCAQGDVTVQIYKLSDFAMRSISEFNGECIDNQNICINRYDFTRESLQGIANGEIVEERLVSHLLKSNCLITSQPDWGSIQICYVGKQLDREKLLRYLVSFREHNEFHEQCVERIFCDLMEFAQPQKLTVYARYTRRGGLDINPFRSNFEGIPENLRMVRQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OR8D1_HUMAN
Sequence: MTMENYSMAAQFVLDGLTQQAELQLPLFLLFLGIYVVTVVGNLGMILLIAVSPLLHTPMYYFLSSLSFVDFCYSSVITPKMLVNFLGKKNTILYSECMVQLFFFVVFVVAEGYLLTAMAYDRYVAICSPLLYNAIMSSWVCSLLVLAAFFLGFLSALTHTSAMMKLSFCKSHIINHYFCDVLPLLNLSCSNTHLNELLLFIIAGFNTLVPTLAVAVSYAFILYSILHIRSSEGRSKAFGTCSSHLMAVVIFFGSITFMYFKPPSSNSLDQEKVSSVFYTTVIPMLNPLIYSLRNKDVKKALRKVLVGK
What is the function of this protein?
Odorant receptor (Potential).  May be involved in taste perception.
What are the official names of this protein?
Olfactory receptor 8D1, OST004, Olfactory receptor 8D3, Olfactory receptor OR11-301, Olfactory receptor-like protein JCG9.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MHPC_ECOHS
Sequence: MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQLDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFLARP
What is the function of this protein?
Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6-oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid.
What are the official names of this protein?
2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase, 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MhpC family.
Protein: PDC1_PEA
Sequence: METETETPNGSTPCPTSAPSAIPLRPSSCDGTMGRHLARRLVEIGVRDVFSVPGDFNLTLLDHLIAEPELNLVGCCNELNAGYAADGYGRAKGVGACVVTFTVGGLSILNAIAGAYSENLPVICIVGGPNSNDYGTNRILHHTIGLPDFSQELQCFQTITCFQAVVNNLDDAHELIDTAISTALKESKPVYISIGCNLPAIPHPTFARDPVPFFLAPRVSNQAGLEAAVEEAAAFLNKAVKPVIVGGPKLRVAKAQKAFMEFAEASGYPIAVMPSGKGLVPENHPHFIGTYWGAVSTSYCGEIVESADAYVFVGPIFNDYSSVGYSLLIKKEKSLIVQPNRVTIGNGLSLGWVFMADFLTALAKKVKTNTTAVENYRRIYVPPGIPLKREKDEPLRVNVLFKHIQALISGDTAVIAETGDSWFNCQKLRLPENCGYEFQMQYGSIGWSVGATLGYAQAATDKRVIACIGDGSFQVTAQDISTMIRCGQRSIIFLINNGGYTIEVEIHDGPYNVIKNWDYTGFVSAIHNGQGKCWTAKVRTEEDLTEAIATATGAEKDSLCFIEVFAHKDDTSKELLEWGSRVAAANSRPPNPQ
What are the official names of this protein?
Pyruvate decarboxylase 1, PDC.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: OTUB1_RAT
Sequence: MAAEEPQQQKQEPLGSDSEGVNCLAYDEAIMAQQDRIQQEIAVQNPLVSERLELSVLYKEYAEDDNIYQQKIKDLHKKYSYIRKTRPDGNCFYRAFGFSHLEALLDDSKELQRFKAVSAKSKEDLVSQGFTEFTIEDFHNTFMDLIEQVEKQTSVADLLASFNDQSTSDYLVVYLRLLTSGYLQRESKFFEHFIEGGRTVKEFCQQEVEPMCKESDHIHIIALAQALSVSIQVEYMDRGEGGTTNPHVFPEGSEPKVYLLYRPGHYDILYK
What is the function of this protein?
Plays a key non-catalytic role in DNA repair regulation by inhibiting activity of RNF168, an E3 ubiquitin-protein ligase that promotes accumulation of 'Lys-63'-linked histone H2A and H2AX at DNA damage sites.  Inhibits RNF168 independently of ubiquitin thioesterase activity by binding and inhibiting UBE2N/UBC13, the E2 partner of RNF168, thereby limiting spreading of 'Lys-63'-linked histone H2A and H2AX marks.  Inhibition occurs by binding to free ubiquitin: free ubiquitin acts as an allosteric regulator that increases affinity for UBE2N/UBC13 and disrupts interaction with UBE2V1.  The OTUB1-UBE2N/UBC13-free ubiquitin complex adopts a configuration that mimics a cleaved 'Lys48'-linked di-ubiquitin chain (By similarity).
What are the official names of this protein?
Ubiquitin thioesterase OTUB1, Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, Ubiquitin-specific-processing protease OTUB1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C65 family.
Protein: FMO1_YEAST
Sequence: MTVNDKKRLAIIGGGPGGLAAARVFSQSLPNFEIEIFVKDYDIGGVWHYPEQKSDGRVMYDHLETNISKKLMQFSGFPFEENVPLYPSRRNIWEYLKAYYKTFIANKDAISIHFSTEVTYLKKKNSQWEITSKDELRTTKSDFDFVIVASGHYSVPKLPTNIAGLDLWFDNKGAFHSKDFKNCEFAREKVVIVVGNGSSGQDIANQLTTVAKKVYNSIKEPASNQLKAKLIETVQTIDSADWKNRSVTLSDGRVLQNIDYIIFATGYYYSFPFIEPSVRLEVLGEGVTGDKHSSVNLHNLWEHMIYVKDPTLSFILTPQLVIPFPLSELQAAIMVEVFCKSLPITTTFDSNACGTHNFPKGKDLEYYAELQELLNSIPRRVGHFEPVVWDDRLIDLRNSSYTDKEERNVLLAEHAQALKKKKAPYFLPAPHT
What is the function of this protein?
Flavin-dependent oxidation of thiol-containing compounds.  Probably required for the correct folding of disulfide-bonded proteins.
What are the official names of this protein?
Thiol-specific monooxygenase, Flavin-dependent monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
Protein: IF2_CLOBL
Sequence: MAKIRVYELAKELNISSKELITLLEEEFSVEVKNHMSAIEDEDADLIKELLSGKEKSEKTKEEDDEIETTAKNPIKESINNKKSNKRDDKNEKVNTENAEDMAIITMTSDTITVKEISDKLEKSYAEVIKELMLMGVMASVNQEINFEMAEKLAAKFDTEILKEEQDEEDDLEDILKDSEEEENLQKRSPIITVMGHVDHGKTSLLDAIRKSKVTSTEAGGITQHIGAYTVELNGESITFLDTPGHAAFTAMRARGAQVTDIVILVVAADDGIMPQTKEAISHCKAAEVPLIVAINKIDRPGANIDKVKQELTEYGLVAEDWGGDTVCVPVSAHTKEGIDELLEMILLSSEILELKANPNRKAKGTVVEAKLDKGRGPVATLLVQNGTLTVGDSIVVGSTYGRIRAMFNDKGENIQSAGPSTPVGILGLSEVPEAGDKFYQVKDEKTARGIADKRKEKIRDEYLQSTHKVSLEDLYNQIREGKVKELGLIVKADVQGSVEALKQSLEKLSTEEVKVRVIHGGVGAINETDVTLATASNGIILGFNVRPDNNAIIASERDGVDIKTYRVIYDAIEDIKSAMLGMLEPEFKEVVIGTAEVRQVYKISSVGTIAGAYVQTGKLARNAGARVIRDGIVIFESELASLKRFKDDAKEVAQGYECGLSIEKFNDIKEGDIIECFIMEEIKKKTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G3PP_METKA
Sequence: MIKAVLFDVDDTLYPSSKLAEEARRNAIRAMIEAGLETDLSEEELYRELQEVVKEYGSNHPRHFDLLLRRIGADPEPKLVAAAVVAYHDTKFAYLKPYPDVIPTLMQLREMGFKLGAVTSGLAVKQWEKLIRLGIHHFFHEVVISEEIGVEKPNPKIFIEAARRLGVKPEEAVYVGDRLDKDIRGANRAGMVTVRIRRGKYQDMEPRNDDDVPDFEIDRPRELLDVVRELAKD
What is the function of this protein?
Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.
What are the official names of this protein?
Glyceraldehyde 3-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: RL17_CUPTR
Sequence: MRHRHGLRKLNRTSSHRLAMLRNMSNSLFQHELIKTTVPKAKELRKVVEPLITLAKKDTVANRRLAFARLRDRDMVTKLFTELGPRYATRPGGYTRILKFGFRQGDNAPMALVELVDRPEITEAPAEEAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: LPAR3_HUMAN
Sequence: MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
What is the function of this protein?
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.  May play a role in the development of ovarian cancer.  Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
What are the official names of this protein?
Lysophosphatidic acid receptor 3, LPA receptor 3, LPA-3, Lysophosphatidic acid receptor Edg-7.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA_PROMH
Sequence: MDKFRVQGPTCLSGEVTISGAKNAALPILFAAILAEEPVELTNVPKLKDIDTTIKLLNRLGTKVERNGSVFVDARHINEFCAPYELVKTMRASIWALGPLVARFGRGQVSLPGGCAIGARPVDLHITGLEQLGAEITLDEGYVKARVDGRLKGAHIVMDKVSVGATITIMTAAVLAEGKTIIENAAREPEIEDTANFLNTLGAKISGAGTDSITIEGVERLGGGTYQILPDRIETGTFLVAAAVSRGRVVCRNAKPDTLDAVLAKLREAGADIETGEDWISLDMHGKRPKAVTLRTAPHPGFPTDMQAQFSLLNLVADGAGMITETIFENRFMHIPELIRMGAHAEIESNTVLCHGVDKLSGAQVMATDLRASASLVLAGCIAEGTTIVDRIYHIDRGYENIEAKLQGLGAKIERLHSND
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GFRAL_RAT
Sequence: MLVFIFLAVRLSSENESSSQTNDCAYFMRQCLTDTDGCKQSWRSMEDACLVSGDSCKINNPLPCNLSIQSLVEKHFQFKGCLCTDDLHCTVNKIFGKKCTNKTDSMKKDNKYKRNLTTPLYHDTGFKQMQSCLEVTEACVGDVVCNAQLALYLKACTANGNLCDVKHCQAAIRFFYQNMPFNTAQMLAFCDCAQSDIPCQQSKETLHSKPCALNVVPPPTCLSVIHTCRNDELCRTYYRTFQTECWPHVAGKCREDETCISMLGKQDLTCSGSDSCRAAYLGTFGTVLQVPCACRSITQGEEPLCMAFQHMLHSKSCFNYPTPNVKDISSYERKHSKEITLTGFNSPFSGELIYVVVCMVVTSGILSLVMLKLRIPSKKRDPAPIEIAGAVIIQ
What is the function of this protein?
Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (Probable).  Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways (By similarity).
What are the official names of this protein?
GDNF family receptor alpha-like.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein; Extracellular side.
Protein: IL17_SHV2C
Sequence: MTFRKTSLVLLLLLSIDCIVKSEITSAQTPRCLAANNSFPRSVMVTLSIRNWNTSSKRASDYYNRSTSPWTLYRNEDQDRYPSVIWEAKCRYLGCVNADGNVDYHMNSVPIQQEILVVRKGHNPCPNSFRLEKMLVTVGCTCVTPIVHNVD
What are the official names of this protein?
Viral interleukin-17, vIL-17, Immediate early gene 13 protein.
What is the protein family that this protein belongs to?
Belongs to the IL-17 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GP67_BPT7
Sequence: MCFSPKIKTPKMDTNQIRAVEPAPLTQEVSSVEFGGSSDETDTEGTEVSGRKGLKVERDDSVAKSKASGNGSARMKSSIRKSAFGGKK
What is the function of this protein?
Plays a role in virion morphogenesis, and is ejected from the infecting particle into the bacterial cell.
What are the official names of this protein?
Protein 6.7, Gene product 6.7, Gp6.7.
What are the subcellular locations of this protein?
Virion. Note=Present in the head of the virion.
Protein: STS1_MAGO7
Sequence: MNVLLTPQPTPFPHQYETSRLSPQRSLSPYTNMTSRKRKADDNEGDEMSVSPLSSPAIPSRHLSRPSKKIRAAEASGRPLPLPRLLETLDTTQLRTVLQKICERHPDIGQEVVNGAPRPSVGSALGILRDYQQRLRGAIPYGQTSSDYTYYRVKQPLMALVDAISDFTPQFLPPIETQVTASLQYLDGATKVVHELPDWDSQAYRQHKDNAYDEISRAWALVITEASKRGGGFVLHTGGWDQMLAKHNQQSGGRLGSAMQAMASNGWIGNNSPNNQNASASSSSGSGAGGDPNSILNQLVNGTYGNPVRVGPW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECO_POLNA
Sequence: MASQRISNEPAYVLHRYDWSESSLILDVFTRHHGRVALVARGAKKPSSSFRPILLPLQPLHVAFGGDAEIRNLKSAEWQGGHVMPSGDALLSGYYLNELLMRLLARDDPHPLLFDAYAATVQLLASQNPDTLQLALRAFELRLLQGIGLLPRLDAETATLTPLAPHQRYVLVAEAGLRQAHDDDRFSLSGAQWQALQQALGGKSLFSDTLQACVACANELKIQLRALLHYHCGVRVLKTRQMMMDLQAL
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: APAG_BRASB
Sequence: MYRAVTRQIEVTVEPNFLPEKSSVADGRWFWSYTVVITNTGEDTVKLRSRHWIITDGVGRQQEVRGEGVVGEQPVLAPGERFEYTSGVPLTTASGFMAGSYQMESASGEQFDIAVPAFSLDSPDGGKRVLN
What are the official names of this protein?
Protein ApaG.
Protein: YBHQ_ECO57
Sequence: MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGLCALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLLAIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR
What are the official names of this protein?
Inner membrane protein YbhQ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y3170_YERPE
Sequence: MPSFDIVSEIDMQEVRNAVENATRDLANRWDFRNVPASFELNEKNESIKVVSESDFQVEQLLDILRAQLSKRGIEGAALEIPEEMARSGKTYSVDAKLKQGIESVQAKKLVKLIKDSKLKVQAQIQGEQVRVTGKARDDLQAVMALVRAADLGQPFQFNNFRD
What are the official names of this protein?
UPF0234 protein YPO3170/y1016/YP_0761.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: CYB_ARTIT
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLGVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWLLRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTELVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDPDMIPSHPYYTIKDILGFLVMLTALATLVLFSPDLLGDPDNYIPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPILHMSKQRSMMFRPLSQCLFWLLVAVLFTLTWIGGQPVEHPYIIIGQTASVLYFLIILFLMPTISLLENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NOT3_YEAST
Sequence: MAHRKLQQEVDRVFKKINEGLEIFNSYYERHESCTNNPSQKDKLESDLKREVKKLQRLREQIKSWQSSPDIKDKDSLLDYRRSVEIAMEKYKAVEKASKEKAYSNISLKKSETLDPQERERRDISEYLSQMIDELERQYDSLQVEIDKLLLLNKKKKTSSTTNDEKKEQYKRFQARYRWHQQQMELALRLLANEELDPQDVKNVQDDINYFVESNQDPDFVEDETIYDGLNLQSNEAIAHEVAQYFASQNAEDNNTSDANESLQDISKLSKKEQRKLEREAKKAAKLAAKNATGAAIPVAGPSSTPSPVIPVADASKETERSPSSSPIHNATKPEEAVKTSIKSPRSSADNLLPSLQKSPSSATPETPTNVHTHIHQTPNGITGATTLKPATLPAKPAGELKWAVAASQAVEKDRKVTSASSTISNTSTKTPTTAAATTTSSNANSRIGSALNTPKLSTSSLSLQPDNTGASSSAATAAAVLAAGAAAVHQNNQAFYRNMSSSHHPLVSLATNPKSEHEVATTVNQNGPENTTKKVMEQKEEESPEERNKLQVPTFGVFDDDFESDRDSETEPEEEEQPSTPKYLSLEQREAKTNEIKKEFVSDFETLLLPSGVQEFIMSSELYNSQIESKITYKRSRDMCEISRLVEVPQGVNPPSPLDAFRSTQQWDVMRCSLRDIIIGSERLKEDSSSIYAKILENFRTLEMFSLFYNYYFAITPLEREIAYKILNERDWKVSKDGTMWFLRQGEVKFFNEICEVGDYKIFKLDDWTVIDKINFRLDYSFLQPPVDTASEVRDVSVDNNNVNDQSNVTLEQQKQEISHGKQLLKQLKQGKISV
What is the function of this protein?
Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover.  The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes.  Preferentially affects TC-type TATA element-dependent transcription.  Could directly or indirectly inhibit component(s) of the general transcription machinery.
What are the official names of this protein?
General negative regulator of transcription subunit 3.
What is the protein family that this protein belongs to?
Belongs to the CNOT2/3/5 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS8_KLEP3
Sequence: MSIEDLARANVRALTPYQSARRLGGKGDVWLNANEFPTAVAFQLTAQTMNRYPEPQPKAVIESYARYADVKPEQVLVSRGADEGIELLIRAFCEPGKDALLYCPPTYGMYSVSAETIGVECRTVPTLADWQLDLPGIEAQLDGVKVVFVCSPNNPTGQIIDPQSIRDLLEMTRDKAIVVADEAYIEFCPQATLAGWLSDYPHLVVVRTLSKAFALAGLRCGFTLANAEVINVLLKVIAPYPLSTPVADIAAQALSAEGIAAMRQRVAQILDERRYLVEQLRGIACVEQVFDSEANYVLARITASSAVFKSLWDQGIILRDQNKQPSLSGCLRITIGTRAESQRVIDALTAENV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: PGL1A_ARATH
Sequence: MGSKMLFSLTSPRLFSAVSRKPSSSFSPSPPSPSSRTQWTQLSPGKSISLRRRVFLLPAKATTEQSGPVGGDNVDSNVLPYCSINKAEKKTIGEMEQEFLQALQSFYYDGKAIMSNEEFDNLKEELMWEGSSVVMLSSDEQRFLEASMAYVSGNPILNDEEYDKLKLKLKIDGSDIVSEGPRCSLRSKKVYSDLAVDYFKMLLLNVPATVVALGLFFFLDDITGFEITYIMELPEPYSFIFTWFAAVPVIVYLALSITKLIIKDFLILKGPCPNCGTENTSFFGTILSISSGGKTNTVKCTNCGTAMVYDSGSRLITLPEGSQA
What is the function of this protein?
Ferredoxin-plastoquinone reductase involved in cyclic electron flow (CEF) around photosystem I.  The homodimer is probably not involved in CEF.
What are the official names of this protein?
PGR5-like protein 1A, chloroplastic, Ferredoxin-plastoquinone reductase 1.
What is the protein family that this protein belongs to?
Belongs to the PGR5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein. Note=Predominantly located in the appressed regions of the thylakoids and less abundant in the stroma lamellae.
Protein: NAGK_ARATH
Sequence: MATVTSNASPKSFSFTVSNPFKTLIPNKSPSLCYPTRNKNHHRLGFSIKATVSTPPSIATGNAPSPDYRVEILSESLPFIQKFRGKTIVVKYGGAAMTSPELKSSVVSDLVLLACVGLRPILVHGGGPDINRYLKQLNIPAEFRDGLRVTDATTMEIVSMVLVGKVNKNLVSLINAAGATAVGLSGHDGRLLTARPVPNSAQLGFVGEVARVDPSVLRPLVDYGYIPVIASVAADDSGQAYNINADTVAGELAAALGAEKLILLTDVAGILENKEDPSSLIKEIDIKGVKKMIEDGKVAGGMIPKVKCCIRSLAQGVKTASIIDGRRQHSLLHEIMSDEGAGTMITG
What is the function of this protein?
Involved in the arginine biosynthetic pathway via the intermediate compound ornithine.
What are the official names of this protein?
Acetylglutamate kinase, chloroplastic, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, AtNAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PDXJ_CAMLR
Sequence: MLLGVNIDHIAVLREARKVNDPDLLEAAFLSANLADQITIHVREDRRHANEKDLENILKYCKCVVNLECSIDMIEYALKYKPSRVTLVPEKRQELTTEGGLNLNNDKLQEVILKLKQEQIEVSLFIDPNLEDIEKSSLLKADFIELHTGLYANIYNALYTNINQTSYALPELILSKNELKKLLENELQRLRQSASLAKSLNLNVAAGHGLNYKNVKNIVDILEIKELNIGQSIVARSVFVGLEKAILEMRALIKR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_CORK4
Sequence: MSDFVRADGRALDEMRPVRIVRGFTTNPAGSVLVEFGNTRVMCTASVEDRVPRFKKDSGEGWLTAEYSMLPSATAERMPRESMRGKVKGRTHEISRLVGRSLRAAIDLKALGENTIALDCDVLQADGGTRTASITGAYVALADALTYLEAEGLVSQNALLPPVAAVSVGLIDGHVCLDLPYEEDSRAEVDMNVVMTESGEFVEIQGTGEHSTFSREQLMQFMDAAEKGCSELIRAQKEALSKPYPKRLPNRKNA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: COPA1_MOUSE
Sequence: MLVKKLAGKGGGRESGSEDPRPLGQRCAGTMPSCTALATLLSVVAVAFCFYLGVKTNDLQARIAALESAKGTPSFHPLSDTVDELKAMVQEKVERLLAQKSYEHMAKIRTAREAPLECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGTPGMDGQKGEPGSPGAAGQSGLPGPKGEPGKEGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGDRGEAGPPGRGERGDPGAPGPKGKQGESGARGPKGSKGDRGDKGDSGALGPRGPPGQKGDPGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGVDGEQGLKGSKGDMGDPGVPGEKGGLGLPGLPGANGVKGEKGDTGLPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGASGLDGKPGSRGADGPIGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPGLDGLDAPCQLGPDGLPMPGCWQK
What is the function of this protein?
Inhibits fibrillization of amyloid-beta peptide during the elongation phase.  Has also been shown to assemble amyloid fibrils into protease-resistant aggregates.  Binds heparin (By similarity).
What are the official names of this protein?
Collagen alpha-1(XXV) chain, CLAC-P.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Note=After proteolytic cleavage, CLAC is secreted.
Protein: PVK1_ERGCA
Sequence: GSSGLISFPRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, ErgCa-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FLBT_RHILO
Sequence: MTNTLKISLKPNEKIYINGAVIRVDRKVTIELMNDVQFLLESHVIQADQASTPLRQLYFIVQVMLINPAGADDAREMFRRSLPLLIASFEDAEICSALKQIDRMVGEDHIYEALKAIRSLYPLERRALGGNDDVPGAPRPLAVGARY
What is the function of this protein?
Has a post-transcriptional repressor function in flagellum biogenesis.  Associates with the 5'-UTR of fljK mRNA and promotes its degradation.
What are the official names of this protein?
Probable flagellum biosynthesis repressor protein FlbT.
What is the protein family that this protein belongs to?
Belongs to the FlbT family.