PharMolix/UniProtQA huggingface dataset:
Protein: SEC13_ASHGO
Sequence: MVTITNAHTELIHDAVLDYYGKRLATCSSDKTIQIFEVDGDSHKLVDSLHGHEGPVWQVDWAHPKFGVILASCSYDGKVLIWKEENGRWSQIAAYEVHSASVNSVKWAPHEYGPLLLCSSSDGKFSVVEFKENGTTSPIIIDAHAIGVNAACWAPATIEDDGQQSQHLRRIATGGADNLVKIWKYNPEANTYLLEDTLAAHADWVRDVAWSPSVLPRAYLATVSQDRTCIIWTQENNQGPWTKTLLKEDKFPDVLWRASWSLSGNILALSGGDNKVTLWKENLEGKWESAAEIEQ
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  It also functions as a component of the nuclear pore complex (NPC).  NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors.  SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
What are the official names of this protein?
Protein transport protein SEC13.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC13 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Protein: SMG_SHEPW
Sequence: MFDILMYLFENYVHSEVEFLVDEDELTKELTRAGFHQAEIIKALTWLEGLAELQEAGTPYLCNHDQQSFRIYTKDELERIDVESRGFLLFLEQIKVLSVETREMVIDRVMQLDESSLNLDDLKWVILMVLFNAPGHESAYEQMEDLIFEQPDGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: COBS_BRUA4
Sequence: MQRNSLIGDTIRSLGFLSRLPLPQRWFEDGDDSLPRNARAFPLAGAVLGLLAGAVLFMAYKVNLPPLACAMLAIGALAAMTGALHEDGLGDTADGFFGASSPDRRLDIMKDSRIGTFAALTLIVFVGLKAALLMTIIDRAGAGYAALALVGCEAASRSGMLAFWHALPSARPGGLSDSVGQPQWETVVCGFGIGLAFLVFTLIPAGGFLSLINALVLATGLLFGFARLCIAKIGGQTGDTLGAAQQIGSVAVLAGLVMAL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DHB13_RAT
Sequence: MNLILELLLLVGIIIYSYLESLVKFFIPQRRKSVAGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKCRKLGAVVHVFVVDCSNRAEIYKSVDQVKKEVGDIEIVVNNAGAIYPADLLSTKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLEPDEVARSLIDGILTNKKMIFVPSYINISLIVEMFFPERVLKAINRIQNIQFEAIVGHRTKRK
What is the function of this protein?
Plays a pivotal role in hepatic lipid metabolism.  In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4.
What are the official names of this protein?
17-beta-hydroxysteroid dehydrogenase 13, 17-beta-HSD 13, Hepatic retinol/retinal dehydrogenase, Short-chain dehydrogenase/reductase 9.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation.
Protein: ACEK_PARP8
Sequence: MNHFPKLLSSQIGFDVAETLLAGFDRHYCIFREAAIRAKNLFEAADWHGLQKLARERITSYDERVRECIAKLEDEYDAENIDDDVWQQIKLHYIGLLTTHRQPECAETFFNSVCCHILHRSYFNNDFIFVRPAISTEYIENDEPAAKPTYRAYYPGKDGLAVTLERIVTNFQLNPPFENLTRDVQCVIQALRDNFGTFNEAPNFQIHVLSSLFFRNKAAYIIGRIINGDMMLPFALPVHHVKPGLLALDALLCKRDQLLIIFSFAHSYFLVDMEVPSAYVEFLGSILHGKPKAEIYTSVGLQKQGKNLFYRDLLRHLKHSSDRFIIAPGIKGMVMLVFTLPSFPYVFKLIKDAFPPPKETTREQVVGKYQLVKRHDRLGRMADTLEYSSVALPLSRLDDALIRELEKEAPSMLEYEGDNLVIRHVYIERRMVPLNIFLQNGTDADIEHGIREYGNAVKELMQANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNVRAVPPPRNEEDEMSGEPWYSVGPHDIFPETYNTFLLGDPRVRESFLKHHADFFDPALWQKQKDYILRGELPDFYPYDRSLRFSIRYPERFAADHVTAATERAA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACS5_ARATH
Sequence: MTSQKRFIFEVEAAKEATDGNPSVGPVYRSTFAQNGFPNPIDGIQSCWDIFRTAVEKYPNNRMLGRREISNGKAGKYVWKTYKEVYDIVIKLGNSLRSCGIKEGEKCGIYGINCCEWIISMEACNAHGLYCVPLYDTLGAGAVEFIISHAEVSIAFVEEKKIPELFKTCPNSTKYMKTVVSFGGVKPEQKEEAEKLGLVIHSWDEFLKLGEGKQYELPIKKPSDICTIMYTSGTTGDPKGVMISNESIVTITTGVMHFLGNVNASLSEKDVYISYLPLAHVFDRAIEECIIQVGGSIGFWRGDVKLLIEDLGELKPSIFCAVPRVLDRVYTGLQQKLSGGGFFKKKVFDVAFSYKFGNMKKGQSHVAASPFCDKLVFNKVKQGLGGNVRIILSGAAPLASHIESFLRVVACCNVLQGYGLTESCAGTFATFPDELDMLGTVGPPVPNVDIRLESVPEMNYDALGSTPRGEICIRGKTLFSGYYKREDLTKEVFIDGWLHTGDVGEWQPNGSMKIIDRKKNIFKLAQGEYVAVENLENVYSQVEVIESIWVYGNSFESFLVAIANPAQQTLERWAVENGVNGDFNSICQNAKAKAFILGELVKTAKENKLKGFEIIKDVHLEPVAFDMERDLLTPTYKKKRPQLLKYYQNVIHEMYKTTKESLASGQ
What is the function of this protein?
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation.  Preferentially uses palmitate, palmitoleate, oleate and linoleate.
What are the official names of this protein?
Long chain acyl-CoA synthetase 5.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: HEM1_HALH5
Sequence: MHILMIGLNYKTAPVEIREKFSFQDSELPQALHQLRQMKSILECTIVSTCNRTELYVVADQLHTGRHFTKTFLADWFKLPKDEFTPFLTIRENDHAIEHLFRVVTGLDSMILGETQILGQVRNSFFIAQEEQVTGSIFNHLFKQAITLAKRAHSETDIGQNAVSVSYAAVELGKKIFDDFKGKQVLILGAGKMGELTAKHLHSNGAEQVTVINRTREKAAELAKRFLGVDRPYNELTEAIVEADILISSTGATGYVVTSDMVSHALKKRKGRPLFMVDIAVPRDLDPALASHDDVYLYDIDDLQNIVQTNLEERRTEAEKIELLIEEELVEFKQWLNTLGVVPIITALRTKALTVQGETMESIERKLPNLTEREKKVLRKHTKSIVNQLLRDPITRIKELANAPEREEALDLFTKIFALEEELAEQEKQEKVKQAEQEWLAKKRPITCMEKQSHVMVKS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MURQ_SALEP
Sequence: MNLGTLVSETRNPQTMDLDALPTPELVKRFNEQDTRVAEAVKATLPDVARAVDAAVAALKSGGRIIYMGAGTSGRLGVLDASECPPTFGVPHGLVVGLIAGGPGALLKAVEGAEDSQQAGEDDLVALNLQEQDLVVGLAASGRTPYVIGGLRYARQSGCTTVAVSCNPDSPIAREANIAISPVVGPEALTGSTRLKSGTAQKMVLNMISTGAMVKFGKVYQNLMVDMKATNVKLVDRACRMVVEATGIGREEAETLLKQTDFEVKPAILMALTGLDAAAAREKLAAHQGFLRAALEH
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: FTSB_KLEP3
Sequence: MGKLTLLLLALLVWLQYSLWFGKNGLHDYTRVNDDVTAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTRPGETFYRLVPDASKRNQASGQQQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: ADA2B_AMBHO
Sequence: AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFRHMWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAAISLPPLIYKGDQGPQPHGRPQCKLNQEAWYILSSSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGATREGESKLPHPMAAGASASAKPPTLTSSLAVAGEANGHSKPTGEEGETLEDPVTSTLPPSWPALPNSDQGQKEGVCETSPEEDDEEEECGPQAVPVSPASAGSPPLQQPQGSRVLATLRGQVLLGRGVGAAGGQWWRRRTQLTREKRFTFVLAVVIGVFVLCWFPFFFSYSLGAICPQHCKVPHGLF
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
What are the official names of this protein?
Alpha-2B adrenergic receptor, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Interaction with RAB26, GGA1, GGA2 and GGA3 mediates transport from the Golgi to the cell membrane.
Protein: Y628_PSE14
Sequence: MSYVIDRRLNGKNKSTVNRQRFLRRYRDHIKKAVEEAVSRRSITDMEHGEQISIPGRDIDEPVLHHGRGGKQTVVHPGNKEFTTGEHIARPQGGGGGKGPGKAGNSGEGMDEFSFQITQEEFLEFMFEDLELPNLVKRNLTGTDTFKTVRAGISNEGNPSRINIIRTLRSAHARRIALSGSSRAKLKEATVELERMKREEPDNFGDIQELEVEIDRLKARIRRVPYLDTFDLKYNLLVKQPNPSSKAVMFCLMDVSGSMTQATKDIAKRFFILLYLFLKRNYDKIDVVFIRHHTSAREVDEEEFFYSRETGGTIVSSALKLMQEIMAERYPSSDWNIYAAQASDGDNWNDDSPICREILTKQIMPFVQYYTYVEITPREHQALWYEYERIGEDYADTFAQQQLVSAGDIYPVFRELFQRRLVS
What are the official names of this protein?
UPF0229 protein PSPPH_0628.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: KAE1_CALMQ
Sequence: MIILGIESTAHTIGVGIVNDNEVLANENETYTPPQGSGIHPREAADHHALKASHLVKRALDKAEVKLSDLDAVAFSQGPGLGPALRVGATVARFIAIKYGKPLVPVHHGVAHIEIAKMTTGAKDPLVLLVSGGHTMVTAYSGGRYRVFGETMDISVGNCLDMFARFLGLPNPGVPHLEECARRGKVMLELPYTVKGQDMSFAGLYTAAVKLVKEGRRVENVCLSIVNTAYYMLAEVTERALALLGKREIVIAGGVARSPILRSIMEIVASEYTATLHVVPPEYAGDNGAMIAWTGLLAYKSGVSISIEDSVIKQRWRIDEVPIPWITSTVS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_MARMM
Sequence: MANIGKRLSAARETFDRDTLYTIDDAVAHVKSNAKAKFDETIELAINLGVDPRHADQMVRGVCNLPNGTGRSVRVAVFAKGPKAEEATKAGADVVGAEDLMEQIQGGNINFDKVIATPDMMPLVGRLGKVLGPRGMMPNPKVGTVTMGVTKAVNDSKGGAVEFRVEKAGIIHAGVGKASFTEAALAENVRALVDAIVKAKPSGAKGLYVRRIALSSTMGPGVKIDTSAAVSA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: KSL1_ISOJA
Sequence: LVKDDMSLILSSFSLFRSSRSSPASASLAGSGHPRTTPPKIASLQSPMVEETKERIAKLFKKKEVSRSTYDTAWVGMVPSPFSSEEPCFPDCLFWLLQNQCPDGSWAQPHHHSLSPSLLNKDVLSSTLASILALQKWGLGQRHIAKGLHFLELNFASATDNSQITPLGFDIVFPAMLDYAADLSLNLRLDPTTLNDLMNRRDSELKRCTENGSAETEVYLAYIGEGMGKLHDWETVMKYQRKNGSLFNSPSTTAAAFIALGNSDCLKYLNSALKKFGSAVPAVYPLDIYSQLCIVDNLERLGISRFFSTEIQSVLDDTYRCWLQGDEEIFMDASTCGLAFRTLRMNGYKVTSDSFIKVVQDCFSSSSPGHMRDVNTTLELYRASELMLYPHEIELEKQNSRLRSLLEQELSGGSIQSSQLNAEVKQALDYPFYAVLDRMAKKKTIEHYNIDDSRILKTSFCLPSFGNKDLLSLSVQDYNRCQAIHREELREFDRWFVENRLDELEFARHKSAYYYCYFAAAATFFAPELSDARMSWAKNALMTTMVDDLFDVTGSVEEMKNLIQLVELWDVDVSTECRSHKVQILFSALKRTICEVGDRAHQLQGRSIRSHIIVIWLDLLHSMMKEVEWSRDKFVPTMDEYVSNAYVSFALGPIVLPALYLVGPKLSEEMVNHSEYHNLFKLMSMCGRLLNDIRGYEREHDDGKLNAMSLYIMNNGGEITPEVAIMEIKSWNDRQRRELLRLVLEEKSVIPKACKDLFWHMCSVVHLFYNKDDGFWSQELIEVVNQVIHQPILLSHF
What is the function of this protein?
Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities (By similarity).  Catalyzes the conversion of ent-copalyl diphosphate (ent-CPP) to ent-atiserene (By similarity).
What are the official names of this protein?
Ent-atiserene synthase KSL1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UVRC_METBF
Sequence: MIDLEALPHLPGCYLFKNEEGTVIYVGKAKDLKKRVSSYFQKREHDPKTASLIEAVRGFDFIVTNTEVEAFLLENTLIKKHWPRYNILLKDSKRYACIHLTEEKFPRIRLSRKKADNGSFFGPFVSAKERDYIFEVVRKTFQLRTCKKMPKRACLRYHIAACSGPCIGAISAEDYAEKVKKAASVLKGNIRELIESMEKDMRELASRQQFEQAMALRDEIAALEYLQEKQNMERQKKHNEDILNYIVRDDTVYLMLFKVYKGTLEDKQDYVFAFGENFLEEFLVQYYSENEPPEELILPEPLEESLVDFLSHVKGTKVKVTVPKQGEKKELLDLALKNVEIGFFGDRKKLEALQSKLSLPKLPNVIECFDISHLSGTSTVGSMVQFRGGRPDKHNYRRFKIESVEGIDDFASIAEVVRRRYSRLLEDKHDLPDLIIIDGGKGQLSSAFQELRKLKVRVPLISIAKREEEIYVPGIKSPLPIKKEEKASLFVQEIRDEAHRFAITYNRLLRQKSMIPKND
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_COXBN
Sequence: MPLLVCGINHQSAPLTVREKLVFTPERTPLALQSLLAEKAVNEALLLSTCNRTEIYTTVDEAATILRWLSKQPQLSGIDLRSFCYARRDIEMVRHVMRVGSGLDSMVLGEPQILGQMKQAYLLARRIGAVGSELGRLFPAVFAATKRIRSETAIGANPVSIAYAVVQLAKRIFSHLNQCQILLIGAGETIELVFSHLYNQGARHFFIANRTLTRAKQIAEPYHAQAIRLSDIPTYLPKVDIVISATMSQLPLVGKGAVESALRQRKRRPLFMADLALPRDIEPETAQLEDVYLYNIDDLQTLIAQNRQTREAAAKQAEAMVEMQAIHYMRQLQVHKAGDTIRRFRERVEMLRDQELEKALAHFQRTNDPKAVIAHFAHNLTNKILHQPTTKLRQAAYEDQVQLLLSAKELFDL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: ADDA_BACCN
Sequence: MMVENWPAKPEGSQWTDDQWKAVVAHGRDILVAAAAGSGKTAVLVERIIKKIINEENPVDVDRLLVVTFTNAAAQEMKNRIGEALEKVLIEEPSSRHIRKQLSLLNKASISTIHSFCLQVIRSYYYMLDIDPRFRIANQTENELLKEEVLDDILEEEYGMEENQLFFELVDRYTSDRNDDDLQRMILALHTAAGAHPNPEKWLDRLVEAYNVEGKTIEDLMYASYLLEDVKFQLETATEHIRKAMELAMLPDGPAPRMETLQTDLVLLETLSHAARKSWTSVYEAMQHVSWQTLKRIKKSDYNEDIVKQVDSLRNKAKDEVKKLQEELFSRKPESFLRDFQEMHPVLGKLVQLVKEFSNRFQAIKRDKGMVDFTDLEHFCLQILSEQGEDGELRPSPVALQYRNRFAEVLVDEYQDTNFVQESIIKLVTKDSEQEGNLFMVGDVKQSIYRFRLAEPGLFLGKYKRFTQEGLEGGMKIDLAKNFRSRHEVLAGTNFIFKQIMGEEVGEIEYDADAELKLGASYPEGEDVAAELLCIHQSEEEVLDGEEGEEVEKAQLEARLIAQRIKAMVDSGYTVYDRKTNEMRQVQYRDFVILLRSMPWAPQIMEELKLQGIPVYAELATGYFEATEVNIMMNVFRVIDNPVQDIPLAAVLRSPIVGLNDEELAMLRAHAKKGSFYEVMRSFLRGAPLEGGKELHEKLKWFYHLLQGWREFARQQSLSDLIWKVYRETGYYDFVGGLPGGKQRQANLRVLYDRARQYEATSFRGLFRFLRFIERILERGDDMGTARALGEQEDVVRIMTIHKSKGLEFPVVFVAGLGRRFNTQDLMQRFLLHKDFGFGSQFIDPRKRIKYTTLSQLAIKRKMKRELIAEEMRVLYVALTRAKEKLILIGTVKDKEKEMEKWLDTREHTEWLLPDYVRASASCYLDWIAPSLYRHRDSEILLELGQGTIPNEIYEYDTSWKVEFVDGKTLLAPEPAQEEKQELLEALREKKAVPLESERKDEVYNRLTWKYEYEDATLQRAKQSVTEIKRNYQSEDGSDTAFIQKLRAPIRTRPRFMEKKGLTYAERGTAVHAVMQHVDLKQSITIESIQEQIAKMVNKEILTFEQAEEISVERIVAFFESHLGKRVLEAKSVEREVPFTMMLSAKEAYQNWQGKSEETILVQGVIDCMIEEDDGITLIDFKTDTIEGKFPGGFDQAKPILEERYKVQLSLYAKALEKTLQHPVKEKCLYFFDGNHVITIEE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: HRCA_NOSS1
Sequence: MQVQLTNRQQHILWATVRHYIATAEPVGSKALVEEYDLGVSSATIRNVMGVLEKSGLLYQPHTSAGRVPSDSGYRIYVDQLITPSLRDTTRAEVLAKEVESALQQHLQWEDWSLEILLQGAAQILASLSGCISLITMPQTNTASVRHLQLMQIETGRIMLILVTDSYETHSKLMDLPPARSETKPDPEVIDRELQIVSNFLNSHLRGRSLLEISTLDWSQLDREFQSYGEFLKNSVAELAHRSAAPAATQIMVRGLAEVLRQPEFSQLQQVKTIIQLLEEEQEQLWRLIFEEPELEDTHKSKVTVRIGAENPLEPIRTCSLISSTYRRGGVPLGSVGVLGPTRLDYESAIAVVAAAADYLSEAFS
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: GP150_HUMAN
Sequence: MEDLFSPSILPPAPNISVPILLGWGLNLTLGQGAPASGPPSRRVRLVFLGVILVVAVAGNTTVLCRLCGGGGPWAGPKRRKMDFLLVQLALADLYACGGTALSQLAWELLGEPRAATGDLACRFLQLLQASGRGASAHLVVLIALERRRAVRLPHGRPLPARALAALGWLLALLLALPPAFVVRGDSPSPLPPPPPPTSLQPGAPPAARAWPGERRCHGIFAPLPRWHLQVYAFYEAVAGFVAPVTVLGVACGHLLSVWWRHRPQAPAAAAPWSASPGRAPAPSALPRAKVQSLKMSLLLALLFVGCELPYFAARLAAAWSSGPAGDWEGEGLSAALRVVAMANSALNPFVYLFFQAGDCRLRRQLRKRLGSLCCAPQGGAEDEEGPRGHQALYRQRWPHPHYHHARREPLDEGGLRPPPPRPRPLPCSCESAF
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 150.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARAA_KLEPN
Sequence: NLDDMRQFAELHDIELTVIDNDTRLPSFKDALRWNEVYYGSKR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: YSZI_CAEEL
Sequence: MSAQLQKIIADNSELIQEKSKKSDQDELGKRIDALLWEVDTLQKNIAETKEMCRRWGDERKREAAEFAKLLDSSDDDQN
What are the official names of this protein?
Uncharacterized protein F15A4.10.
Protein: KV12_RABIT
Sequence: ADIVMTQTPSSVSAAVGGTVTIKCQASESIGNELAWYQQKPGQPPKLLIYRASKLASGVSSRFKGSGSGTEFTLTISGVQCDDAGIYYCQQDWNSNNVVNNFGGGTEVVVK
What are the official names of this protein?
Ig kappa chain V region 3368.
Protein: SYGA_PROMH
Sequence: MQKFDTKTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPIAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVIIKPSPDNIQELYLGSLRELGLDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWCDGPLGKTTYGDIYHQNEVEQSTYNFEYADVDFLFSCFEQYEKEARELLELEKPLPLPAYERILKAGHTFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCKK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_SHELP
Sequence: MYNESPIIRRPSTRIYVGDVPIGDGAPIAVQSMTNTRTTDVEATVAQIRALENVGADIVRVSVPTMDAAEAFKVIKQQTKVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRSVVECARDKNIPIRIGVNGGSLEKDLMDKYKEPTPQALLESAMRHVDILDRLNFDQFKVSVKASDVFLAVESYRLLAKQIKQPLHLGITEAGGARAGAVKSAVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVIATVNELERRLEDVVTPMDVSIIGCVVNGPGEALVSDIGLTGGNRKSGYYDDGVRQKERFDNEHIVDQLEAKIRAKVASVDARIPTTDITE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: MURG_BIFLD
Sequence: MNQGTPHIVLAGGGTAGHVNPLLAVAGAIRDIEPTAQVTVIGTAVGLEKDLVPEAGYELDTIEKVPFPRRPNLYMLRFPAKWKRETAKVRSILETRHADVVAGFGGYASAPVYATAHKMGIPIAIHEQNARAGMANKLGARWADFIGTVYEGTGLKPRAGADVERVGLPLRPAIASLTKRIGDDRAAVRRESAAQLGVDPNRPLVLVTGGSLGAQSLNRAIASSAADLLAHAQIIHLTGRGKISEVRELVTASAGADVLTGIGPESAGQGDYHTAEYLERIDLAFACADLVICRAGAGSVSELAALGLPAIYVPLPIGNGEQRFNAEPVVNAGGGLLVADKDLTPQWVHEHVPDLLADHERLAEFGRKAWEYGIRNAAEIMARHVLQLAEPSK
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VATB_PYRAB
Sequence: MSKEYSTISKIYGPLMIVEGVKGVAYGEVVEIETESGEKRKGQVLDARENLAIVQVFEGTRDLDVKTTSVRFTGETLKVPVSMDMLGRIFNGIGKPIDGGPEIIPEDRRDVHGAPLNPVARAYPRDFIQTGISAIDGMNTLVRGQKLPIFSGSGLPHNQLAAQIARQAKVLGEEESFAVVFAAMGITYEEANFFKKSFEETGAIERAVLFLNLADDPAIERIITPRMALTVAEYLAFDYDMQVLVILTDMTNYCEALREISAAREEVPGRRGYPGYMYTDLATIYERAGRIRGKKGSITQMPILTMPDDDITHPIPDLTGYITEGQIVLSRELHRKGIYPPIDVLPSLSRLMKDGIGKGRTREDHPQLAQQLYAAYAEGRSLRDLVAVVGEEALSETDKKYLEFADRFEREFVAQGYYEDRSIEETLDLGWELLSILPESELKRVKKEMIMKYHPKYRKRSS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: SDS23_YEAST
Sequence: MPQNTRHTSIVEMLSTPPQLPNSTDLNSLSEQTDKNTEANKSDTESLHKSISKSSSSSSLSTLDNTEYSNNNGNSLSTLNSQNLLSVHRQEWQHTPLSNLVEQNKLIFIRGSISVEEAFNTLVKHQLTSLPVENFPGDMNCLTFDYNDLNAYLLLVLNRIKVSNDKITSDCQNGKSVPVGEIVKLTPKNPFYKLPETENLSTVIGILGSGVHRVAITNVEMTQIKGILSQRRLIKYLWENARSFPNLKPLLDSSLEELNIGVLNAARDKPTFKQSRVISIQGDEHLIMALHKMYVERISSIAVVDPQGNLIGNISVTDVKHVTRTSQYPLLHNTCRHFVSVILNLRGLETGKDSFPIFHVYPTSSLARTFAKLVATKSHRLWIVQPNDNQPTASSEKSSSPSPSTPPVTTLPSLASSYHSNTQSSRMANSPVLKSSDTSNNKINVNINLSGPSPSQPQSPSATMPPPQSPSNCPASPTPAHFEKEYRTGKLIGVVSLTDILSVLARKQTHHKEIDPQMARKQRGHIG
What is the function of this protein?
Involved in DNA replication and cell separation during budding.
What are the official names of this protein?
Protein SDS23.
What is the protein family that this protein belongs to?
Belongs to the SDS23 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.