PharMolix/UniProtQA huggingface dataset:
Protein: PKNI_MYCTO
Sequence: MALASGVTFAGYTVVRMLGCSAMGEVYLVQHPGFPGWQALKVLSPAMAADDEFRRRFQRETEVAARLFHPHILEVHDRGEFDGQLWIAMDYVDGIDATQHMADRFPAVLPVGEVLAIVTAVAGALDYAHQRGLLHRDVNPANVVLTSQSAGDQRILLADFGIASQPSYPAPELSAGADVDGRADQYALALTAIHLFAGAPPVDRSHTGPLQPPKLSAFRPDLARLDGVLSRALATAPADRFGSCREFADAMNEQAGVAIADQSSGGVDASEVTAAAGEEAYVVDYPAYGWPEAVDCKEPSARAPAPAAPTPQRRGSMLQSAAGVLARRLDNFSTATKAPASPTRRRPRRILVGAVAVLLLAGLFAVGIVIGRKTNTTATEVARPPTSGSAVPSAPTTTVAVTAPVPLDGTYRIEIQRSKQTYDYTPTPQPPDVNTWWAFRTSCTPTECLAAATMLDDNDHTQAKTPPVRPFLMQFGEGQWKSRPETVQFPCVGPNGSPSTQATTQLLALRPQPQGDLVGEMVVTVHSNECGQQGAVIRIPAVASRSGDLPPAVTVPDPATIPDTPDTTSTATLTPPTTTAPGPGR
What is the function of this protein?
Plays an important role in slowing down the growth of mycobacteria within the infected host.
What are the official names of this protein?
Serine/threonine-protein kinase PknI.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Single-pass membrane protein.
Protein: SSRP_SALA4
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKNAGR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ATPB_LACDA
Sequence: MSQGEIVQVIGLVVDVKFSIGKDLPDINNALKVIKSDDDSIILEVILEQGDGVLRCIAMESTDGLRRGMKVEDTGSSISVPVGPDTLGRVFNVLGQPIDGGPEFPADHPRSGIHKEAPKYDELTTSREILETGIKVIDLLEPYLRGGKVGLFGGAGVGKTTIIQELIHNIAQEHNGISVFTGVGERTREGNDLYFEMKASGVLDKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGQLQERITSTKKGSITSIQAVYVPADDYTDPAPATTFAYLDATTNLERSLVEQGIYPAVDPLESTSSALDPEIVGQEHYDVATRVQHILQRYRELQNIISVLGMDELSDEEKLIVARARRIQFFLSQNFFVAEVFTSVPGSYVPIKETIKGFKMILDGHLDDLPEDAFRGVGPIEDVLKKALKMGVTPSDPEAKALLEK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: KAX6A_OPICA
Sequence: MNAKFILLLVLTTMMLLPDTKGAEVIRCSGSKQCYGPCKQQTGCTNSKCMNKVCKCYGCG
What is the function of this protein?
Inhibits Kv1. 2/KCNA2 and Kv1. 3/KCNA3 and weakly inhibit Kv1. 1/KCNA1 voltage-gated potassium channels (PubMed:29483648).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 6.10, OcKTx5.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 06 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TRI14_HUMAN
Sequence: MAGAATGSRTPGRSELVEGCGWRCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNTQLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGELCHPVPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSPSPERSLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPVLRFDALWQVLARDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRLP
What is the function of this protein?
Plays an essential role in the innate immune defense against viruses and bacteria (PubMed:30150992, PubMed:32404352).  Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways (PubMed:24379373).  Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593).  Acts as a scaffold between TBK1 and STAT3 to promote phosphorylation of STAT3 and resolve interferon-stimulated gene (ISG) expression (PubMed:32404352).  Inhibits the transcriptional activity of SPI1 in a dose-dependent manner (By similarity).
What are the official names of this protein?
Tripartite motif-containing protein 14.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane. Cytoplasmic vesicle, phagosome.
Protein: MRAY_SYNC1
Sequence: MLYHLLYPLHEQFSVLYIFRYITFRAIYATITALMIAFILGPWLIDKLSRLQIGQSIRKDGPQSHFKKEGTPTMGGTLILLAIVLPTLLWTDLTNVYVWVTLLVTVGFGAVGFVDDYRKVKLRNSAGLSARQKMLWLMLIAGTAGVMLYSYPPFQTTLAFPFFKGLRPELGLFYIPFAVLVIVGASNAVNLTDGLDGLAIGPTIIASGTYLLFAYLAGNARLAEYLQISSVQGAGELAVLCGAMVGAGLGFLWFNTYPAQVFMGDVGSLSLGGALGTIAVITKQEIVLVIVGGIFVVEALSVIVQVSSFKLLGKRIFRMAPIHHHFELKGWAEPKIIVRFWIISIILALVALSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRAS1_ECOLI
Sequence: MITQQIISSELEVLKKHIDSGDIRIPSLWQGLKPGLIIMGWMIFCPLLMSFLITQKTSETLTAVLAGGWLGLIILFIVARIRMLYFSLPEEFLKTSSVMRVISSKLKVYFIVYMGVIFLWSFLGGGIIYGFGAILVTVIMAFLIQLDIGRYQFVGVIDAINSYVKNKKLSRVK
What is the function of this protein?
Involved in surface exclusion.
What are the official names of this protein?
Protein TraS.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: FRMD8_XENLA
Sequence: MDGSETSHSSGLNDFLLRSSVSSGSRSMDVIIYLINDEVIQLTVDGLSVITAHELHKSIREALQLPETAQDVFALWLISPLLEVQLKPKHQPYKVCRQWHDLLARFTNCSSNDILQDEPYLQFRRNIFLPKARELQISHERILYLLYEEAKYNVLEGRYPCDVEDCEVLGGLACRLELGPYNQNEHTPATIRPKLDTLFPPYLCKKRNGGLLTTFKNRGGRQASFEQTVLNTYKEVKETSACTDEQAMKNHYKEYLKKCHELPYYGCAFFQGDVDKPAQGFLNRSGRKAVSVSVNLEGVSVIDRKEKHVLISLTYPELSWDHTYPDEDEHILWLEFDGESEGTPVNKLLKIYSKQAELMSGLIEYCIELSQSTESPASDSTPGNSQLSEKRSKLKRQESVLCNRMKHLTTIDYVEDGAKITRVKPKRTASFFTRQNTHNYSAVQPSETPTES
What is the function of this protein?
Promotes the cell surface stability of RHBDF1 and RHBDF2 and prevents their degradation via the endolysosomal pathway.  By acting on RHBDF proteins, involved in ADAM17-mediated ligand shedding (By similarity).  May negatively regulate Wnt signaling (By similarity).
What are the official names of this protein?
FERM domain-containing protein 8.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane.
Protein: HLDD_PARXL
Sequence: MTLIVTGAAGFIGSNLVKALNERGEQRIIAVDNLTRADKFKNLVDCEIDDYLDKTEFVERFRRGDFGKVRAIFHEGACSDTMETDGRYMMDNNFRYSREVLDVCLAQNIQFLYASSAATYGGSSRFVEEREVEQPLNVYGYSKFLFDQVIRRVLPTAKSQIAGFRYFNVYGPRETHKARMASVAFHNFNQFRAEGKVKLFGEYNGYAAGEQTRDFVSVEDVVKVNLFFFDNPDKSGIFNLGSGRAQPFNDIASTVVNTLRSLNNEPALSLAEQVQRGLIEYISFPDALRGKYQCFTQADQSKLRAAGYDAPFLSVQEGVDRYVRWLFGQV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: COPA_STAES
Sequence: MANTTLTLDIIGMTCAACSNRIEKKLNRMNHVQAKVNLTTEKATIDYESDDYHLEDFVEQIQSLGYDVAVEQVELNINGMTCAACSNRIEKVLNQTQGVQQATVNLTTEQALIKYYPSATNTEALIKRIQNIGYDAETKTSSKAQSNRKKQELKHKRNKLIISAILSLPLLLVMVVHISPISIPSILVNPWVQLILSTPVQFIIGWQFYVGAYKNLRNGSANMDVLVAVGTSAAYFYSIYEMMMWLTHQTHHPHLYFETSAILITLILLGKYLEARAKSQTTNALSELLNLQAKEARVIKENKEIMLPLDKVKVGDTLLIKPGEKIPVDGKVTKGDTSIDESMLTGESIPVEKSSGDSVIGSTMNKNGSIMIEATQVGGDTALSHIIKVVEDAQSSKAPIQRLADIISGYFVPIVVSIAVITFIIWIIFVHPGQFEPALVSAISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGQFVERAHYVDTIVLDKTGTITNGQPVVTDYVGDNDTLQLLASAENASEHPLADAIVTYAKDKGLNLLDNDTFKSIPGHGIKATIHQQQILVGNRKLMNDYNISISNKLNDQLNHYEHLGQTAMMIAVDNQINGIIAVADTVKNDAKQAIKELRNMNIDVVMLTGDNNRTAQTIAKQVGIEHVIAEVLPEEKAHQISLLQDKGKQVAMVGDGINDAPALVKADIGMAIGTGAEVAIEAADITILGGDLLLVPKAIKASKATIKNIRQNLFWAFGYNVAGIPIAACGLLAPWIAGAAMALSSVSVVMNALRLKKMKL
What is the function of this protein?
Involved in copper export.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSME_CHLTE
Sequence: MNNPRGAFVQGAEAYGRFLEVFIDGHWWVVGDALENIGKTTKRLGANAYPHLYGGSSGLKGSSPKYSGYATPSKEVKSRFEK
What is the function of this protein?
Component of the photosynthetic apparatus.  The light harvesting B740 complex binds bacteriochlorophyll c.
What are the official names of this protein?
Chlorosome protein E.
What is the protein family that this protein belongs to?
Belongs to the BChl C/E-binding protein family.
What are the subcellular locations of this protein?
Chlorosome, chlorosome envelope.
Protein: YNFA_ECO24
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QTRT2_CAEEL
Sequence: MVKFQIEKKTLLGRLGKIDTWGSVEVNHQTPSFQTYLRAGHIPHLTWEVAENQLKLEQTHIFQMTLPTLVSNAKIIEKFGKGAAKFCGMPAGAAVHLTPFDPLGKLPGGYNDSKSVAIWTANGKVSLDVKMWREIINSFGCGSIETLVDYDTPKDVGQKKLVKAVDRTKTFQEQLFQQDEKVNGERIVSLGGGFSKYHRRKCAVDVGLAENIAGYTVEFREFTEGKETDDKEMKELLEETFSPLPPTKLRCISGPFNPKTVLFLVQQGIDLFDSSFPVKLAEEGHAFCLSDDFPTSSKYEVVDFNNEKFADDFTALFDGCACYTCTKYTKGYLQHLLNTRELLASILLVIHNMTEYDKMFKLIRSSLENSEGL
What is the function of this protein?
Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase accessory subunit 2, Queuine tRNA-ribosyltransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RELL2_BOVIN
Sequence: MSEPQPDLEPPQHGLYMLFLLVLVFFLMGLVGFMICHVLKKKGYRCRTSRGSEPDDAQLQPPEDDDMNEDTVERIVRCIIQNEANAEALKEMLGDSEGEGTVQLSSVDATSSLQDGAPSHHHTVHLGSSAPCIHCSRNKRPPLVRQGRSKEGKSRPRPGETTVFSVGRFRVTHIEKRYGLHEHRDGSPTDRSWGSGGGQDPGGGQGPGGGQPRTGMPAIESLPPERPQPPALASTPMQNGGLRDSSRVPRALEGNPGASAEPMLGAGGRGPSPGPARKEANGQPSKQDTSDHQVSPPRGAGGV
What is the function of this protein?
Induces activation of MAPK14/p38 cascade, when overexpressed.  Induces apoptosis, when overexpressed.
What are the official names of this protein?
RELT-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the RELT family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GPMA_DELAS
Sequence: MYKLVLIRHGESTWNLENRFTGWTDVDLTATGVEQAKNAGRLLKAEGYDFDLAYTSVLKRATRTLWHTLDEMDRTWLPVQHSWRLNERHYGGLQGLNKADMAKQYGDAQVLVWRRSYDTPPPALEPQDPRSERSDVRYAQLDPSQVPLTECLKDTVARVLPFWNESIAPAILSGKRVVVAAHGNSIRALIKYLDGISDDAIVGVNVPNGIPLVYELDANLKPIRHYYLGDAEAAAKAAAAVAAQGKA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: DENR_DANRE
Sequence: MATTENAESGSPENKVDRADPDAKYPLKVLYCGVCSLPAEYCEYMPEPAKCKQWLEKNFPDVFAKLTLGTAPKQESKGGGGGEDGGGGRGRGEAPPAGEEEEKKKQKRGGRGQIKQKKKTVPQKVTIAKIPRAKKKYVTRVCGLATFDIELKEAQRFFAQKFSCGASVTAEDEIIIQGDFTDDIIDVIQEKWPEVDDDSIDDLGEVKK
What is the function of this protein?
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon.  Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes.  Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).
What are the official names of this protein?
Density-regulated protein, DRP.
What is the protein family that this protein belongs to?
Belongs to the DENR family.
Protein: 3SX3_MICCO
Sequence: MKTLLLTLVVVTIMCLDLGYTLVCYTNVLEPPGTLETCPDDFTCVKKWEGGGRRVTQYCSHACAIPASYEFVHCCQTDKCNG
What is the function of this protein?
Has been described to inhibit nicotinic acetylcholine receptor (nAChR) alpha-7/CHRNA7 subunits and to bind acetylcholine binding protein (AChBP) (Kd=29. 5 nM) (PubMed:21214917).
What are the official names of this protein?
Three-finger toxin MicTx3, MCOR0100C, Three-finger toxin 3FTx-3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ENGB_RICAH
Sequence: MINNEKAVNNKRSTDGGKLFRSQVKFVAGAMNINQIPNFSLPEIAFVGKSNVGKSSLINTICNNKNLAKVSNTPGRTRQINFFNLADKLIIVDLPGYGFAHVPISVKEQWEVLISYYLRNSHNLRLVNLLIDSRRGIKENDQKVAELLLANKREFQIIFTKSDKVIDCKNLNNEVQNFLATLNYSCNVMYVSSRSKEGARALKASLAKCIKA
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RPOC1_PROM2
Sequence: MTNSNLRTENHFDYVKISIASPQRIMDWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGYIKLAAPVSHVWYLKGIPSYVAILLDIPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAEDSIIENEPIVGIGAEALKQLLEDLDLNQVAEELREEITNSKGQKRAKLIKRIRVIDNFIATNAKPEWMVLDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRALKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQKADDEVMQVLQEVIDGHPILLNRAPTLHRLGIQAFEPKLVGGRAIQLHPLVCPAFNADFDGDQMAVHVPLALEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPNYQKPEFGDNKTTFASLEDVIFAFEDKRLSLHEWVWVRFNGEVEDEDEMRSPQKTQELEDGSKLEIWNLRRDRFDSDNNLISRFVLTTVGRVVMNYTIIDSVSKT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit gamma, RNAP subunit gamma, RNA polymerase subunit gamma, Transcriptase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
Protein: AN18B_HUMAN
Sequence: MRKLLSFGRRLGQALLSSMDQEYAGRGYHIRDWELRKIHRAAIKGDAAEVEHCLTRRFRDLDVRDRKDRTVLHLACAHGRVQVVTLLLDRKCQINICDRLNRTPLMKAVHCQEEACAIILLKRGANPNIKDIYGNTALHYAVYNEGTSLAERLLSHHANIEALNKEGNTPLLFAINSRRQHMVEFLLKNQANIHAVDNFKRTALILAVQHNLSSIVTLLLQQNIHISSQDMFGQTAEDYAFCCDLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRKKLKKRKEGAKAEHNLKVASEEKQERLERSENKQPQDSQSYGKKKDEMFGNFMLKRDIAMLKEELYAIKNDSLRKEKKYIQEIKSITEINANFEKSVRLNEEMITKKVAQYSQQLNDLKAENARLNSKLEKEKHNKERLEAEVESLHSNLATAINEYNEILERKDLELVLWRADDVSRHETMGSNISQLTDKNELLTEQVHKARVKFNTLKGKLRETRDALREKTLALESVQLDLKQAQHRIKEMKQMHPNGEAKESQSIGKQNSSEERIRQRELENLLLERQLEDARKEGDNKEIVINIHRDCLENGKEDLLEERNKELMNEYNYLKEKLLQYEKEKAEREVIVREFQEELVDHLKKFSMSESPLEGTSHCHINLDETWTSKKKLFQVEIQPEEKHEEFRKVFELISLLNYTADQIRKKNRELEEEATGYKKCLEMTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNEVLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQAIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVECKFSKMKTAYEDVTTELEEYKEAFAVALKANSSMSEKITKSDKKIAVISTKLFMEKERMEYFLSTLPMRPDPELPCVENLNSIELNRKYIPKMAIRIPTSNPQTSNNCKNSLTELLLRWALAPIYFLL
What are the official names of this protein?
Ankyrin repeat domain-containing protein 18B.
Protein: COX1_ORYSJ
Sequence: MTNLVRWLFSTNHKDIGTLYFIFGAIAGVMGTCFSVLIRMELARPGDQILGGNHQLYNVLITAHAFLMIFFMVMPAMIGGFGNWFVPILIGAPDMAFPRLNNISFWLLPPSLLLLLSSALVEVGSGTGWTVYPPLSGITSHSGGAVDLAIFSLHLSGVSSILGSINFITTIFNMRGPGMTMHRLPLFVWSVLVTAFLLLLSLPVLAGAITMLLTDRNFNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGIISHIVSTFSRKPVFGYLGMVYAMISIGVLGFLVWAHHMFTVGLDVDTRAYFTAATMIIAVPTGIKIFSWIATMWGGSIQYKTPMLFAVGFIFLFTIGGLTGIVLANSGLDIALHDTYYVVAHFHYVLSMGAVFALFAGFYYWVGKIFGRTYPETLGQIHFWITFFGVNLTFFPMHFLGLSGMPRRIPDYPDAYAGWNALSSFGSYISVVGIRRFFVVVAITSSSGKNKRCAESPWAVEQNPTTLEWLVQSPPAFHTFGELPAIKETKS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: BICRD_DROME
Sequence: MHKPKLANAITAAAIASSISTKNNNNNSIVGGSSSSSSGGNKSKRPRQFGQYSIGVGTGAGAGGLLRSDDSGFDHLDYSSLIGDSIDLEHYISAMEARRHDQEPDVWAQLQQKESDILLAAELGKALLEKNEELVKQQEKLIEDYSSKIEKLEQEKHVLRQKLAIAEDESDQRVLELQSDLTELKDKLQTQDTAIRQAEKEKTILIDELQHQNTRLTEQIQEAHATELKLSAQIQELKDQYHYRNSSLQEHVNSLESIKTELNLTTGKRQELERRLQIAQEEKESLTSSLEESSDRIHMLERHAREQETKLETTLQALERSQRENNVLSERLGADTNSSTPGRKSLQFEMECDEDDGSYTETGKPNQMFVEARSVYIQLKSLVDSLKVSHDDDSGLNSDISLELESMDNTISSSERHEDGHLAIEFRQGMLSSMSDELTRLLLNLDAGNFKKMLDQTRNLVLEQEDEIKRSHQLIQQLEAKVTVTDVELQNVKEERDQARGDLEDNTDRDELLSKAQTERDAANDRRTKAEVELAKTRVELMQANSQLLESIQQKVELSQQLEQWQMDMHELIDEQMRSKLINNRRAMAAESSAPSPPSSAAANLAKRVTSYKLWSLFQR
What are the official names of this protein?
Bicaudal D-related protein homolog, BICD-related protein homolog.
What is the protein family that this protein belongs to?
Belongs to the BICDR family.
Protein: RL31_BRUA4
Sequence: MKANIHPDYHTIKVVMTDGTEYMTRSTWGKEGDTMNLDIDPTTHPAWTGGSQTLLDRGGRVTKFKNRFGNLGI
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: CIDEC_BOVIN
Sequence: MAMYTAVSTSVVTQQQLSEPSAEAPRARPCRVTTADRSVRKGIMVHSLEDLHVKVRDTLMLAYKPFFLVLEEDGTTVETEEYFQSLADDTVFMVLHKGQKWQPPSEQSTRYQLALSHKPAKIDVARVTFDLYKVNPQDFIGCLNVKATLYGTYSVSYDLHCSGAKRIMKEALRWALFSMRTTGHMLLGTSCYLQQLLDATEREQPPKSKAASLIPTSLKMLQ
What is the function of this protein?
Lipid transferase specifically expressed in white adipose tissue, which promotes unilocular lipid droplet formation by mediating lipid droplet fusion.  Lipid droplet fusion promotes their enlargement, restricting lipolysis and favoring lipid storage.  Localizes on the lipid droplet surface, at focal contact sites between lipid droplets, and mediates atypical lipid droplet fusion by undergoing liquid-liquid phase separation (LLPS) and promoting directional net neutral lipid transfer from the smaller to larger lipid droplets.  The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair.  Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1.  May also act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (By similarity).  When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment (By similarity).
What are the official names of this protein?
Lipid transferase CIDEC, Cell death-inducing DFFA-like effector protein C.
What is the protein family that this protein belongs to?
Belongs to the CIDE family.
What are the subcellular locations of this protein?
Lipid droplet. Nucleus. Endoplasmic reticulum. Note=Diffuses quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby enabling its rapid enrichment at lipid droplet contact sites.
Protein: DEF1_BORBR
Sequence: MALLSILRYPDPRLHKTAKPVAVVDDRIRQLVRDMADTMYDAPGVGLAATQVDVHERVVVIDVSEEGNDLRVLINPEITWKSDERQTYEEGCLSVPGIYDEVERAARIRCKALDQQGQPYEFEADGLLAVCVQHEIDHLDGKVFVEYLSNLKQNRIKTKLKKAEREAERA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.