PharMolix/UniProtQA huggingface dataset:
Protein: CAH_BRADU
Sequence: MRTTSVGVFKIVTKGPGDVSGLMAMIGSGAIDPKSILAVLGKTEGNGGVNDFTREYAVAALCTALAPQLGLSPEEVEQRIAFVMSGGTEGVLSPHITVFTRREVERRPAGLSGKRLSIGMAHTRDFLPEELGRAAQIAETAAAVKAAMADAGIADPADVHFVQIKCPLLTSDRVEAASARGNKTATTSAYGSMAYSRGASALGVAVALGETGSDISDGDVLRRYDLFSKVASTSAGIELMHNVVIVLGNSAASASEFEIGHAVMNDAIDAAAVTSALKCVGLGVAPQAEAGRELVNIFAKAEASPDGSVRGFRHTMLEDTDISSTRHARAAVGGLIAGLAGTGAVYVSGGAEHQGPAGGGPVAVIARLSD
What is the function of this protein?
Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine.  Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
What are the official names of this protein?
Cyanuric acid amidohydrolase, CAH.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: GCSH_STAAC
Sequence: MAVPNELKYSKEHEWVKVEGNVAIIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
What is the function of this protein?
Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate.
What are the official names of this protein?
Glycine cleavage system H protein, Octanoyl/lipoyl carrier protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: GPDL4_ARATH
Sequence: MINMRDNPTMHVLQASKFLFLALILIQLLSTQLFAQRSKSPWQTLTGDAPLVIARGGFSGLLPDSSLDAYSFVSQTSVPGAVLWCDVQLTKDAIGLCFPDVKMMNASNIQDVYPKRKTSYLLNGVPTQDWFTIDFNFKDLTKVILKQGILSRSAAFDGNSYGISTVKDISTQLKPEGFWLNVQHDAFYAQHNLSMSSFLLSISKTVIIDYLSSPEVNFFRNIGRRFGRNGPKFVFRFLEKDDVEVSTNQTYGSLAGNLTFLKTFASGVLVPKSYIWPIESQYLLPRTSFVQDAHKAGLEVYASGFGNDFDLAYNYSFDPLAEYLSFMDNGDFSVDGLLSDFPLTASSAVDCFSHLGSNASSQVDFLVISKNGASGDYPGCTDLAYTKAIKDGADVIDCSLQMSSDGIPFCLSSINLGESTNVVQSPFRNRSTTVPEIGSLPGIYSFSLAWSEIQTLRPAIENPYSREFTMFRNPRERSSGKFVSLSDFLNLAKNSSSLTGVLISVENATYLREKQGLDAVKAVLDTLTEAGYSNKTTTTRVMIQSTNSSVLIDFKKQSRYETVYKVEETIRDILDTAIEDIKKFADAVVISKKSVFPTSESFTTGQTKLVERLQKFQLPVYVEVFRNEFVSQPWDFFADATVEINSHVTGAGINGTITEFPLTAARYKRNSCLTRKDVPPYMIPVQPAGLLTIVSPASLPPAEAPSPVFTDADVTEPPLPPVSARAPTTTPGPQSTGEKSPNGQTRVALSLLLSAFATVFASLLLL
What is the function of this protein?
Involved in primary cell wall organization.  Required for the accumulation of crystalline cellulose.
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase GDPDL4, Glycerophosphodiester phosphodiesterase-like 4, ATGDPDL4, Glycerophosphodiesterase-like 1, Protein SHV3-LIKE 1.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: SSTT_SALPB
Sequence: MATQRASGLLQRLAQGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAQDIVPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLGFALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPVGIFGLVSSTLATTGFSTLWGYAHLLVVLIGCMLLVALVVNPLLVFWKIRRNPYPLVFACLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGVPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAACQAEDERLANNALRS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRI60_MOUSE
Sequence: MDSTALKILQDKCICYICSDFMEDPVTSRCGHNFCFACLRLLWDDLQGNIFCPVCQTPFPPKSFSRNYQFRNMTETIRLLQKRQSKRKRQEEHTVCPKHDQPLVLFCVRDRDVLCTQCSLSVEHQGHYTCPIKKASSYHRKVLESAIATLKFGVKQVEEKLAVQHRRVLGLREEAQYQKIEIRYEIGQIKLFLQSEYEAHLNESHMEELRSFSELNGYLETLLDHVSTAKDLLKEVEAIHERSDVTLLRAYHKLQNLKSPKPWLFRTKQYGLSLPAQYSGLSRIIKQFQADVTFDRDTAHPQLVISEDRKSVFYKEAWPCVCASPQKFHLWPALLGCKGFDSGRQYWEVKVGDKPRWTLGVCQAHFSGDWSNQSSGFWAIGRYAENSYVTYGPLRTEFLPVVRPSKVGIFLDYELGELSFYNMNDRSLLYTFRNSFTSTLWPYFYIGTDSESLEILTHPTPDTGSY
What are the official names of this protein?
Tripartite motif-containing protein 60, RING finger protein 33.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
Protein: Y4791_ARATH
Sequence: MTFLLFQLLVLLRYSIGFHCKIDNNGVKSVTSKKNDDEKIVISRNWKAAISLDFIFIVFPMLLFFTVLSEWVYHGTGLLSLLVLILSVTAKRSFSGLQRGQSLSFRASVSSYRVALMLITCLCILAVDFTIFPRRYAKTETYGTSLMDLGVGSFVLANAVVSRQARDVSSGNWITGIKATAPLLLLGFIRLVTTSGVDYQVHVTEYGVHWNFFFTLAAISILTSFVNIPAKYCGLLGFAVLAGYQTWLLSGLNTYLLSDERGTDIISKNKEGVYSILGYWGMYLLGVHLGYRLFYGKHTNIRSTTSSIARVFLVSLLLWIVTILFDNYVERISRRTCNMPYVTWVLAQDLQALGIFMLSSYIPLNKLSSLEEAIDQNLLATFLLANLVTGMVNLTVDTIFASPFSSLLILTAYAFALSAIIGTIHFSGFRLKFW
What are the official names of this protein?
Uncharacterized protein At4g17910.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL33_YERPE
Sequence: MAKGVREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVLYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL32_DEIRA
Sequence: MAKHPVPKKKTSKSKRDMRRSHHALTAPNLTECPQCHGKKLSHHICPNCGYYDGRQVLAV
What is the function of this protein?
Forms a cluster with L17 and L22, and with L22, a pair of 'tweezers' that hold together all the domains of the 23S rRNA.  Interacts with the antibiotic troleandomycin which blocks the peptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MNMA_GEOUR
Sequence: MVKNNKRKRVVIAMSGGVDSSVAAALLKEEGHEVIGISMQVWDYTRFTAEEGEKFDTCCSLDDIHDARRVAEQLEIPFYVVNFEEEFQNLVIDDFVNEYLLGRTPNPCVRCNQWIKFELLLKKARGLGADMIATGHYARTEQDADGRYRLMKGVDPAKDQSYFLFTLTQEQLAMTLFPLGGMTKQEVRALAAGYGLRVAEKGESQEICFVPDNDYVRFIEEERGKQLLSGNIVDRKGKVLGVHDGTYRYTVGQRKGLGIAHPEPLYVLGVDAARKEVTVGPRDALYSDGLIATAINWIAPTPETAIEASCKIRYRHHPIPCRILPLADNRAEVRFTEREKSVTPGQAVVFYDGDTVLGGGWIEHAVNTKTAVSHE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BURMS
Sequence: MGNEFQHRTVLLDEAVDALVTRPDGVYVDGTFGRGGHSRAVLARLGDAGRLIAFDKDPRAIETAESIEDARFEIVHDSFAAMKGALDARGVGRVSGVLLDLGVSSPQVDDPARGFSFRANGPLDMRMDPTRGESAAEWLARASVQELTEVIRDYGEERFAFQIAKAIVARRAESDRLGPLDSTGELAQIVGHVVKTREKGKDPATRTFQAIRIHVNQELADLQVVLEAALSLLEQGGRLVVISFHSLEDRIVKRFLQAHASAPAVDRRLPIRAADLPRPPLKLLGRMFPNDAEVAANPRARSAVMRIAERVAP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SWNA_ARTBC
Sequence: MHLEFEKAHDVLLEDVRDTVNIRQTHFSSPKRLANRWDHRLSDESLSQGASPLKNSVKTATTSVPIPLGVGRPASLFYPWQSMTMTGTKESNTRNPMTCNIGEAAFDISSALNYADPSGSTELVACFRENTRLIHNPPYQDWDTTLTCGSTSAIDIVLRMLCNRGDWILAEASTYTGTVMAAKAHGLNIQSIEMDEEGLLPVDLDNKLRYWDTSRSRKPFVLYTIPSGHNPTGITQSTARKAAIYQIAERHDLLVLEDDPYFFLRLDGSFSSLDINPPYSSFEKLRKSLPSSYLSLDKSGRVIRVDSTSKILAPGLRCGWLTASKQIVEIFENFAEVGPAPPSGPSQVMLYKLFVESWGQEGFANWLNHLSGEYKSRRDIMIAACSQHLPKGLCTWTTPTHGMFLWITIDLARHPDYSEKRENLSLDLEDKIYERAASYGVAVAKGSWFNVEACLDKVFFRITFVSTTCLDDLENGVKRLGAAVRDEFRFTQA
What is the function of this protein?
Aminotransferase; part of the gene cluster that mediates the biosynthesis of swainsonine (SW), a cytotoxic fungal alkaloid and a potential cancer therapy drug (PubMed:28381497).  Swainsonine production occurs via a multibranched pathway and is dispensable for fungal colonization of plants and infection of insect hosts (By similarity).  The first step of swainsonine biosynthesis is the production of the precursor pipecolic acid (PA) via conversion of L-lysine (Lys) to 1-piperideine-6-carboxylate (P6C) by the aminotransferase swnA, the latter being further reduced to PA by the reductase swnR (By similarity).  The PKS-NRPS hybrid synthetase swnK uptakes and condensates PA and malonyl-CoA with and without skipping of the ketoreductase (KR) domain in order to produce 3 intermediates, 1-oxoindolizidine, (1S)-1-hydroxyindolizin, and (1R)-1-hydroxyindolizine; with the transisomer (1S)-1-hydroxyindolizin being predominant (By similarity).  The terminal thioester reductase (TE) domain of swnK is involved in reduction of the thioester bond to release the intermediate aldehydes (By similarity).  The oxidoreductase swnN could contribute to the reduction of 1-oxoindolizidine to (1S)-1-hydroxyindolizin and (1R)-1-hydroxyindolizine, contributing to the major route of SW production (By similarity).  The dioxygenase swnH2 would be responsible for the oxidization of (1R)-1-hydroxyindolizine into (1R,2S)-1,2-dihydroxyindolizine and of (1S)-1-hydroxyindolizin to yield both (1R,2S)-1,2-dihydroxyindolizine and (1S,2S)-1,2-dihydroxyindolizine (By similarity).  The dioxygenase swnH1 then performs the conversion of the 1,2-dihydroxyindolizine epimers to SW (By similarity).
What are the official names of this protein?
Aminotransferase swnA, Swainsonine biosynthesis gene cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Protein: CISY_IGUIG
Sequence: MTLLTASSRAAARLLGAKNSSCIIFAARHASTSTNLKDVLANMIPKEQARIKSFRQQYGSTVIGQITVDMLYGGMRGMKGLIYETSVLDPDEGIRFRGYSIPECQKLLPKAPGGAEPLPEGLFWLLVTGEIPSQEQVNWVSREWAKRAALPSHVVTMLDNFPTNLHPMSQLSAAVTALNSESTFARAYSEGISRTKYWEFIYEDSMDLIAKLPCIAAKIYRNLYREGSSIGAIDPALDWSHNFTNMLGYTDPQFIELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLAFAAAMNGLAGPLHGLANQEVLVWLTNLQKELGEDVSDQKLRDFIWNTLNSGRVVPGYGHAVLRKTDPRYTCQREFALKHLPKDPLFKLVAQLYKIVPNVLLEQGKAKNPWPNVDAHSGVLLQYYGMKEMNYYTVLFGVSRALGVLSQLIWSRALGFPLERPKSMSTDGLMVLVGAKSG
What are the official names of this protein?
Citrate synthase, mitochondrial, Citrate (Si)-synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: GCSH_ACAM1
Sequence: MSFEYPDNLKYMDSHEYVRLEGDVATVGITAFAIDQLGDIVFIELPEVGDELSQGETMGNIESVKAVEDIYAPINGTVLECNTAIADAPEQLAEDPYNNGWLLKIKVSGPAALDKAMSASDYQAKVEG
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: VG64_BPML5
Sequence: MKKIIATALIAGSAILGLSACTSDADVASENVSKAADNFEINRRIVFFNGITDKYLLEIQGRCSINADTASKKLDVTCKTKDGIKKHFLGLSDNVSYFMEQVDGANVSTDFYQVNFKPQAILPDIELR
What are the official names of this protein?
Gene 64 protein, Gp64.
Protein: UFL1_DROMO
Sequence: MSSDWDEIKRLAADFQKAQLTSTLQKLSERNCIEIVTLLLEKQLLDVVFTNDGKEYITPEHLEREIQDELYANGGRANLVEVSKTLNVDLSRIEALAERIAADNPQIHLMLGQLIDEDYITHIAQEINEKLSQRGEISISDLTSQFDLPSEFLQHNVMEKHLGKTIKGRQDATNPRVFFTQAYIQRCKAKIRGALAAITKPTNVSVILQQINVQEKIFHSLLDEIMPAGQVTSKQANAQYVPHIYAKTQAEWVNSFYKQNSFLEYEAINKLGISDAKAYIRKQFPNEQFLFLKRVALGAHLIELTVVSALNECSATKQYLDLATILPSNLSEEDIEEAFDAVMAQKHCNPSQFVYLQSIVFSQAYLTQLIQPCHDMAHALAKAAIDSGAYQQYIVEKTLAQKGSNSSANFDADDDGKVDKRDERRKKAASGKAGGGAQGRETKTKSTKKHQRGRAAAHNHDSDDDEETTQQSAGSSRKSVKPLELVKSSDVINRIKSTLEEEGLEHLAKPIAGLFVNQLNQAALAKAQELYEATPQTNRRQTHAAIQERVNTLLVDLRLYEKGIKLFNTDTQAQLIKYLLKSLGNDICNELTLYVAAECSLSVKMTNLNVDQRIKLIQECDAQYRNALLEQNKALNKSIEDFELATEAVLKTCSMIIKKADKKKDRALIVSHKEKLMQQLSECREPALLLHLAALILFTTITGCILHASGKFVSTILQHIRPTLNESQNALLLRYHDLVLQMLQQGTTDSPESKSLNEQLQTLQAEVVDLAQNFSRVSVSKAD
What is the function of this protein?
E3 UFM1-protein ligase that mediates ufmylation of target proteins.
What are the official names of this protein?
E3 UFM1-protein ligase 1 homolog, E3 UFM1-protein transferase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UFL1 family.
Protein: PSBT_OENAR
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKIQTKKTK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NRTD_SYNY3
Sequence: MHLEITDLNRVFVGKRGSVVALKNINMHIETGEFVCAVGASGSGKSTLLRLIAGLDTPTSGTINVDGQRVTGPGADRGMVFQHYSLFPWMTVRQNVEFGLKLQGCSQKERFDTASYYLDVVGLINFSEAYPRELSGGMKQRVAIARSLACHPKVLLMDEPFGALDIQTKERMHEYLIDIWQRLQCSILMITHDVEEAVFLAQRVYVLSSRPGTIQRELTINLPGDEETPKNRTYKIKREPEFFKYSDEISSLLRGRETEETEAIAS
What is the function of this protein?
Part of the ABC transporter complex NrtABCD involved in nitrate uptake.  The complex is probably also involved in nitrite transport.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nitrate import ATP-binding protein NrtD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nitrate/nitrite/cyanate uptake transporter (NitT) (TC 3.A.1.16) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NFUA_VIBVY
Sequence: MSNITITEAAQTHFANLLGQQPDGTNIRVFVVNPGTQNAECGVSYCPPEAVEATDTEIPYQSFSAYVDELSLPFLEDAEIDYVTDKMGSQLTLKAPNAKMRKVADDAPLLERVEYAIQTQVNPQLAGHGGHVKLMEITDAGVAIVAFGGGCNGCSMVDVTLKEGIEKELLQQFSGELTAVRDATEHDRGDHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: DSBB1_BURL3
Sequence: MNDYTLAIRRERRLLMLLGWVCIALLAGALYLQYVKNEDPCPLCIIQRYFFCAIGIFAFLAAGIRNWRGVWVLELLIAIAAAGGVGTAARHLTIQMNPGFSCGFDTLQPIVDSLPPAQWFPGMFKVAGLCETVYPPIFGILLPGWSLIGFAVILIAVVASLWRHRRKLVG
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B 1, Disulfide oxidoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PURA_NEIG1
Sequence: MAKNVVVIGAQWGDEGKGKIVDWLAEEAGGVVRFQGGHNAGHTLVVGGKKTILRLIPSGILHEGLDCFIGSGVVVSPEALLGEIDELNAAGVKNVEGRLKIAPTCPLILPYHIALDQAREASRGKGKIGTTGRGIGPAYEDKVARRAIRAADLLHPEKLREKLDAVLAYYNVQLQYLHNAGPVKAEDVMAVIEKVAPRIAPMIADVSRVLNEKNKNGEKLLFEGAQGALLDIDYGTYPFVTSSNCLAGAASAGAGVGPQMLDYVLGIVKAYTTRVGSGPFPTELFDEVGAGLAERGHEFGSVTGRARRCGWFDAAALKRSIQINGISGMCITKLDVMDGVETINICVGYELPGGGKTDILPCGSDAVETCKPIYETMPGWRESTVGVKSYDALPANAKAYLKRIEEVCGAPVAIVSTGPDREETIVLHHPFA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXA_CAMC1
Sequence: MKNIHQTAVIEDGAIIGDDANIEAYAFVSKDAVLGNNVTIKQGARVLGKTRIGDNSRVFSYAIVGDIPQDISYKDEVDTGVIIGEHATIREFCTINSGTHKGDGITRIGDNAFIMAYSHIAHDCIIGSNVILANNATLAGHVELGDYAVVGGLTPIHQFVRVGESCMVAGASALSQDVVPFCLAEGNRAYIRSLNLVGIRRRFDKEQVEELVRAYKFLFNQGISLKDQANELIAKTSDENVKKMCKFILETTRGIPLAKGRD
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_FRAT1
Sequence: MREKIRLVSSAKTGHFYTTTKNKKEMPNKMEIKKYDPVVRKHVMYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: UBA5_DROME
Sequence: MSHAIDELQAIIADLKTELETEPKSSGGVASNSRLARDRIDRMSAEVVDSNPYSRLMALQRMNIVKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVAAAAATLSFINPDVEIETHNYNITTVENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINAACNERNLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLGYNALSDFFPKMTLKPNPQCDDRNCLVRQKEFQARPKPVLIEEKAVSEEPLHATNEWGIELVAEDAPESNTTPAETPVMGEGLRLAYEAPEKSSETSEETVSAATADETSLEDLMAQMKSM
What is the function of this protein?
E1-like enzyme which activates UFM1.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 5, Ubiquitin-activating enzyme 5, UFM1-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family. UBA5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Golgi apparatus.
Protein: IST1_HUMAN
Sequence: MLGSGFKAERLRVNLRLVINRLKLLEKKKTELAQKARKEIADYLAAGKDERARIRVEHIIREDYLVEAMEILELYCDLLLARFGLIQSMKELDSGLAESVSTLIWAAPRLQSEVAELKIVADQLCAKYSKEYGKLCRTNQIGTVNDRLMHKLSVEAPPKILVERYLIEIAKNYNVPYEPDSVVMAEAPPGVETDLIDVGFTDDVKKGGPGRGGSGGFTAPVGGPDGTVPMPMPMPMPSANTPFSYPLPKGPSDFNGLPMGTYQAFPNIHPPQIPATPPSYESVDDINADKNISSAQIVGPGPKPEASAKLPSRPADNYDNFVLPELPSVPDTLPTASAGASTSASEDIDFDDLSRRFEELKKKT
What is the function of this protein?
ESCRT-III-like protein involved in cytokinesis, nuclear envelope reassembly and endosomal tubulation (PubMed:19129479, PubMed:26040712, PubMed:28242692).  Is required for efficient abscission during cytokinesis (PubMed:19129479).  Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells (PubMed:19129480, PubMed:19129479).  During late anaphase, involved in nuclear envelope reassembly and mitotic spindle disassembly together with the ESCRT-III complex: IST1 acts by mediating the recruitment of SPAST to the nuclear membrane, leading to microtubule severing (PubMed:26040712).  Recruited to the reforming nuclear envelope (NE) during anaphase by LEMD2 (PubMed:28242692).  Regulates early endosomal tubulation together with the ESCRT-III complex by mediating the recruitment of SPAST (PubMed:23897888).
What are the official names of this protein?
IST1 homolog, hIST1, Charged multivesicular body protein 8, CHMP8, Putative MAPK-activating protein PM28.
What is the protein family that this protein belongs to?
Belongs to the IST1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Nucleus envelope. Note=Localizes to centrosome and midbody of dividing cells (PubMed:19129480, PubMed:19129479, PubMed:20719964). Colocalized with SPART to the ends of Flemming bodies during cytokinesis (PubMed:20719964). Localizes to the reforming nuclear envelope on chromatin disks during late anaphase.
Protein: RPOB_LISMC
Sequence: MSGHSGHDVKYGRHRTRRSFARISEVLELPNLIEIQTASYQWFLDEGLREMFRDISPIEDFAGNLSLEFIDYDLGEPKYSVEESKNRDANYAAPLRVKLRLINKETGEVKDQEVFMGDFPLMTEMGTFIINGAERVIVSQLVRSPGVYFNGKLDKNGKKGFGSTVIPNRGAWLEYETDAKDVVHVRIDRTRKLPVTVLLRALGFGSDQEIIDLIGDNDYLRNTLEKDNTDNAEKALLEIYERLRPGEPPTVDNARSLLVSRFFDPKRYDLASVGRYKINKKLHLKNRLFNQTLAETLVDPETGEIIASKGDILDRRNLDQIIPNLENGVGFRTLRPTDGVMEDSVLVQSIKIYAPNDEEKEINIIGNAYIEENVKHITPSDIISSISYFFNLLHGVGDTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDMTTITPQQLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRERAGYEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSFAKVNKFGFIETPYRRVDPETNRVTDKIDYLTADEEDNYVVAQANSKLDEQGTFTEEEVMARFRSENLAVEKERIDYMDVSPKQVVSVATACIPFLENDDSNRALMGANMQRQAVPLMHPEAPFVGTGMEHVSAKDSGAAVTAKHDGIVEHVEAREIWVRRVSLVDGKEVTGGIDKYTLRKFVRSNQGTCYNQRPNVAEGDRVVKGEILGNGPSMDSGELALGRNVLVAFMTWDGYNYEDAIIMSERLVKDDVYTSIHIEEFESEARDTKLGPEEMTRDIPNVGEDALRDLDERGIIRVGAEVKDNDLLVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGGGGIVLDVKIFTREAGDELPPGVNQLVRVYIVQKRKIHEGDKMAGRHGNKGVISRILPEEDMPFMPDGTPVDIMLNPLGVPSRMNIGQVLELHLGMAARALGIHVATPVFDGANEEDVWSTVEEAGMARDAKTILYDGRSGEAFDNRISVGVMYMIKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTIKSDDVVGRVKTYEAIVKGESVPEPGVPESFKVLIKELQSLGMDVKMLSADEEEIEMRDMDDDDFTNQNDAFNIVQPENAAAEKTE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RH31_ORYSJ
Sequence: MFDFGLSEDDSELGEVDEDDGPSGFEDDLFDDEGGEKNLVESPAKNSAPFESIKGEPIDQEGVVHTRESGGGDSYLSQTRFDECSLSPLTLKGVKAAGYERMTAVQEATLPIILKGKDVLAKAKTGTGKTVAFLLPAIEVVSKLPPIDCDKKRPPISVVVVCPTRELADQAAAEANKLLKFHPSIGVQLVIGGTRMALEQKRMHTNPCQILVATPGRLKDHMENTPGFATRLMGVKVLILDEADRLLDMGFRTDIERIVAALPKQRQTLLFSATVPDEVRQVCHIAMKRDLEFVNTVEEGSEETHSQVKQMHVVAPLDKQFSILYGLLTDHISENVDYKVIVFCTTAKVTSLVAELLSELKLNVREIHSRKPQSYRTRISKEFKESKGLILVSSDVSARGVDYPNVTLVVQMGVPTDREQYIHRLGRTGRRGNEGSGILLLAPWEEYFLRSIKDLPITEATLPLIDLDTKRKVEKALAHVEVKDKELAYQAWLGYYNSNKFIGRDKYQLVSLANEFSRSLGLNNPPAVPKLVLRKMGLNNIPGLRSK
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 31.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family.
Protein: PSAD_CHLRE
Sequence: MAVMMRTQAPAATRASSRVAVAARPAARRAVVVRAEAEAAPAAAKKAAEKPAWTVPTLNPDTPSPIFGGSTGGLLRKAQTEEFYVITWEAKKEQIFEMPTGGAAIMRQGPNLLKFGKKEQCLALTTQLRNKFKLTPCFYRVFPDGKVQYLHPADGVYPEKVNAGRVGANQNMRRIGQNVNPIKVKFSGRMMSPAEI
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.  PSAD may encode the ferredoxin-docking protein.
What are the official names of this protein?
Photosystem I reaction center subunit II, chloroplastic, Photosystem I 20 kDa subunit, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: UPPP_BLOPB
Sequence: MSMIYITLNIIAYVIDVRSLILDVRRLVFSLILGIVEGLTEFLPISSTGHMILVENILNCMDDSVIAFTVIIQLGAILSITKIFWSQLYGMSMICIKKIFFKQHDDHNHLCIRHIFLGTFPGIMLGMIFYEKIGLIFELTYIMYGLIIGGIFLLVGELCASKEPRVSRINNITYLQAFLIGCFQCLAFWPGFSRAGATIGGGLVVGLDRRISSEFSFFLAVPIIFGSAVLTLYHYRSCIGLMDVLLLIAGSATAFFIALFTVRYFLKIVKNVSLIPFAIYRFLLAGGIYWGLMT
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.