PharMolix/UniProtQA huggingface dataset:
Protein: TOP2B_MOUSE
Sequence: MAKSSLAGSDGALTWVNNATKKEELETANKNDSTKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVSKLIEVVKKKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEDSQNQHDDSSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTTVVKVEFDEEFSGTPAEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPTSTGKTNAKKVKKRNPWSDDESKSESDLEEAEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAAAADDSNDLEELKVKASPITNDGEDEFVPSDGLDKDEYAFSSGKSKATPEKSSNDKKSQDFGNLFSFPSYSQKSEDDSAKFDSNEEDTASVFAPSFGLKQTDKLPSKTVAAKKGKPPSDTAPKAKRAPKQKKIVETINSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKPSKTASKKPKKTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFN
What is the function of this protein?
Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.  Plays a role in B-cell differentiation.
What are the official names of this protein?
DNA topoisomerase 2-beta, DNA topoisomerase II, beta isozyme.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus.
Protein: ACT2_ORYSI
Sequence: MADAEDIQPLVCDNGTGMVKAGFAGDDAPRAVFPSIVGRPRHTGVMVGMGQKDAYVGDEAQSKRGILTLKYPIEHGIVSNWDDMEKIWHHTFYNELRVAPEEHPILLTEAPLNPKANREKMTQIMFETFSVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDSLMKILTERGYSFTTSAEREIVRDIKEKLAYVALDYEQELETAKSSSSVEKSYELPDGQVITIGAERFRCPEVMFQPSLIGMEAPGIHETTYNSIMKCDVDIRKDLYGNIVLSGGSTMFPGIADRMSKEITALAPSSMKIKVVAPPERKYSVWIGGSILASLSTFQQMWISRAEYEESGPAIVHRKCF
What is the function of this protein?
Essential component of cell cytoskeleton; plays an important role in cytoplasmic streaming, cell shape determination, cell division, organelle movement and extension growth.
What are the official names of this protein?
Actin-2.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ISPF_PSEE4
Sequence: MRIGHGYDVHRFCDGDFITLGGVRIPHKYGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVVGIVDNKGWKVGNVDATIVAQAPKMAPHIETMRQQIAADLQVELDQVNVKATTEEKLGFTGREEGIAVHAVALLLPA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ALL15_CARMA
Sequence: AGPYSFGL
What is the function of this protein?
May act as a neurotransmitter or neuromodulator.
What are the official names of this protein?
Carcinustatin-15.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR12_SOLLC
Sequence: MPTIKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNSQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSKYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NDHH_LOLPR
Sequence: MSLPLTRKDLMIVNMGPQHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNAPEFLENIQIPQRASYIRVIMLELSRIASHLLWLGPFMADLGAQTPFFYIFRERELIYDLFEAATGMRMMHNYFRIGGVAADLPYGWIDKCLDFCDYFLRGIIEYQQLIKQNPIFLERVEGVGFISGEEAVNWGLSGPMLRASGIQWDLRKVDLYESYNQFDWKVQWQKEGDSLARYLVRISEMRESIKIIQQAIEKIPGGPYENLEVRRFKKAKTSEWNDFEYKFLGKKPSPNFELSKQELYVRVEAPKGELGIYLVGDDSLFPWRWKIRPPGFINLQILPQLVKKMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: KEX1_ASPNC
Sequence: MASWLLSTLLFLSPSLVSAKSAADYYVHSLPGAPEGPLLKMHAGHIEVDPQNNGNLFFWHYQNRHIANRQRTVIWLNGGPGCSSMDGALMEVGPYRLKDNETLTYNEGSWDEFANLLFVDQPVGTGFSYVNTDSYLHELDEMSAQFIVFLEEWFRLFPEYERDDIYIAGESYAGQHIPYIAKAIQERNKNVQGKTIASWNLKGLLIGNGWISPNEQYMSYLPYAYEEGLIKEGSRTAKELEVLQSVCKSRLETGKNKVHLNDCEKVMNALLDKTVEDNKCLNMYDIRLRDTTDACGMNWPTDLEDVKPYLQREDVVKALNINPEKKSGWVECSGAVSSAFNPQKSPPSVQLLPGLLESGLQILLFSGDKDLICNHVGTEQLINNMKWNGGTGFETSPGVWAPRHDWSFEGEPAGIYQYARNLTYVLIYNASHMVPYDLPRQSRDMLDRFMNVDIASIGGSPADSRIDGEKLPQTSVGGHPNSTAAEEQEKERIKETEWKAYAKSGEAVLLVVIIGVLVWGFFIWRSRRRHQGYRGVWHKDMSGSSVLERFHNKRTGGADVEAGDFDEAELDDLHSPDLEREHYAVGEDSDEDDISRQHSQQASRAGGSHNLS
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase kex1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: PMBA_HAEIN
Sequence: MKPAENSTALLKAQEQELRQAVSFAVELATKAGASAEVAVTKVSGLSVSARLQEIENVEFTNDGALGISVYMGQQKGNASTSDLSESAIKNAVEAALAIAKYTSPDDCTGLADKDLMAFDAPDLELYHAADIDVDKATELALQAEQAALQADERIINSNGASFNSHTGVKVYGNSHGMLQSYLSSRYSLSCSVIGGVEDALENDYEYTISREFDKLQSPIWVGENCAKKVVSRLNPQKLSTREVPVIFLNDVATGIISHFAAAISGGSLYRKSSFLLDHLGKQVLPDWFSISERPHLLRRLASTPFDSEGVRTQDREIVENGILQTYLVTSYSGKKLGMSSTGHAGGIHNWLVKPNLTGGLTALLRQMGTGLLVTDVMGQGVNIVTGDYSRGASGFWVENGEIQYPVAEITIAGQLQDMLKNMLAVADDIEHRSNIQTGSILLDKMKISGN
What is the function of this protein?
Probable metalloprotease.
What are the official names of this protein?
Metalloprotease PmbA homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase U62 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSC2_ARATH
Sequence: MAIAEVIGFFTLVCVIWYWVYKKHKNLQLKICRSSIESSSSSSSLSSPPSLSSPISRTWTHQVFPSFRGEDVRKGFLSHIQKEFKSKGIVPFIDDEMKRGESIGPGLFQAIRESKIAIVLLSKNYASSSWCLNELVEIMNCREEIGQTVMTVFYQVDPSDVRKQTGDFGKAFKKTCVGKTQEVKQRWSRALMDVANILGQDSRKWDKEADMIVKVAKDVSDVLSYTPSRDFDDYVGIRPHITRINSLLCLESSDVRMIGILGPPGIGKTTIARVLYDQISEKFQFSAFIENIRLSYWKGWHDEGNLDFPVEIMTGDRQRKLNLQRRLLSELFNQKDIQVRHLGAVQERLRDHKVLVILDGVDQLEQLTALAKETQWFGYGSRIIITTQDQRLLRAHEINHVYKVDLPATDEALQIFCLYAFGQKFPYDGFKKLAREFTALAGELPLGLRVLGSYLRGMSLEEWKNALPRLRTSLDGEIEKTLRFAYNVLSDKDKSLFLHIACLFNGCQVNHVKQWLANSSLDVNHGFEVLSNKSLISTDMGLVRMHSLLQQLGVDIVRKQSIGEPEKRQFLVDVNEISDVITDNTGTGTILGIMLHVSKIEDVLVIEETVFDRMTNLQFLILDECLRDKLNLPLGLNCLPRKIRLLRWDYCPLSIWPSKFSAKFLVELIMRANKFEKLWEGIQPLKNLKRMELGDARNLKEIPDLSNATNLESLLLSFCTSLLEIPSSIRGTTNLKELDLGGCASLVKLSSCICNATSLEELNLSACSNLVELPCALPGDSNMRSLSKLLLNGSSRLKTFPEISTNIQELNLSGTAIEEVPSSIRLWSRLDKLDMSRCKNLKMFPPVPDGISVLNLSETEIEDIPPWVENLSQLRHFVMIRCKKLDNISLSRISKMEGVHCLQITRGDEDVSGDSIVNIRWYSNFPNQWTLQSDMLQICLPELVYTSPVSLHFISNEFKTIPDCIKNLSQLHQLSFYRCHKLVSLPQLSDCLSSLDAENCVSLETIDGSFHNPDIRLNFLNCNNLNQEARELIQKSVCKHALLPSGEVPAYFIHRAIGDSVTIHLKERHLPLYLIFKASLVLFNDDEINYDYDDDDDDDYDEEVIVYGDYDSYPHSDDYTKQETMRLSCRVEGKQNGLTIQYGSSVHLLPTPHRYTEHVYIFEASFSLGECNSPEAESELVFDFKVHDYFWAIKECGLRLLELPHAHGDD
What is the function of this protein?
TIR-NB-LRR receptor-like protein involved in plant defense.  Acts as a trigger of hypersensitive response (HR).  Functions as guard of CAMTA3, a negative regulator of immunity, during pathogen infection.
What are the official names of this protein?
Disease resistance-like protein DSC2, Protein DOMINANT SUPRESSOR OF CAMTA3 NUMBER 2.
What is the protein family that this protein belongs to?
Belongs to the disease resistance NB-LRR family.
Protein: KDSA_ALISL
Sequence: MQNQKTVKIGNIDVANDKPFTLFAGMNVLESRDLAMRMCETYVEITDRLGIPYVFKASFDKANRSSVHSYRGPGMEEGLKIFQELKDTFGVKIITDIHTEAQAQPVADVVDVIQLPAFLARQTDLVETMARTGAVINVKKPQFMSPDQVGNIVDKFAECGNENIILCERGSCMGYDNLVVDMLGFGVMKKVSNGSPIIFDVTHSLQNRDPSGKASGGRRSQTVELAKAGLATGIAGLFIEAHPTPDKALCDGPSALPLDQLEPFLKQMKALDDLIKGFEHIDIK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PACC_ASHGO
Sequence: MSHINHLLNSDEAIPSTALRSCAQRSPMSSDDELVGTAGYRENQPVPGSTLPTSPSDVSTDTENDEHQRLLCQWDACGSEFSQPELLYHHLCQDHVGRKSQRNLQLNCHWGSCTTKTVKRDHITSHLRVHVPLKPFSCSTCSRKFKRPQDLKKHLKVHMEDTMKERSRAAPGSRGVRKTGVNKGSALQEKARTLPNLTVESFVSQEMQNYYPYYKSRQHLDETLSHIILPPPAALGGTLASEPPSYTRKAVSFFTTLSQDMSRRLPSLAPCNSPGPAGKMVMLPRPEQQYARVPRYPAMPELPPLVTSPGAESHALPRGHNFRPAPLIPGSMLPSLSRFSHDKSQFVARNSYSLNQKASLNEELCENELDIALENLALDDTDALRAELQTVNIIKDYLTCLLLEDVYTESFELPASVEKSHSTLRKYPQIKV
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including palB/RIM101 itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ISK13_HUMAN
Sequence: MAAFPHKIIFFLVCSTLTHVAFSGIFNKRDFTRWPKPRCKMYIPLDPDYNADCPNVTAPVCASNGHTFQNECFFCVEQREFHYRIKFEKYGKCD
What is the function of this protein?
May be a serine protease inhibitor (By similarity).  Essential for sperm maturation and fertility.  Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity).
What are the official names of this protein?
Serine protease inhibitor Kazal-type 13, Hepatitis B virus DNA polymerase transactivated serine protease inhibitor, Hespintor, Serine protease inhibitor Kazal-type 5-like 3.
What are the subcellular locations of this protein?
Secreted. Note=Secreted into the lumen of the initial segment of the epididymis and binds to sperm. In the initial segment of epididymis, localizes on the dorsal surface of the acrosomal region of sperm, gradually becomes more restricted to the acrosomal region in spermatozoa during epididymal transit (By similarity).
Protein: BIOB_SULSY
Sequence: MEILNNLAERVISGEKLTKEEGLQILSIPDELVMDLVEEASKVRKYFFKNQMEFCSLINAKNGACTEDCSFCAQSSHYKTPINAYGLVSKDEMLAGAEKAVAINANRYCIVVSGRKASKEEVDKIADAIKEIKKTYPIKVCCSLGTVDEKDLDKLKVAGVDRINHNLETSEKYFSKIVSTHTWKERYKTIKKIQKVGLSTCTGGIFGMGESDEDIIDLAMTYRDLEVDSIPLNFLIPIPGTPLGDKHNLTPLRCLKIIALFRLFNPKSEIRLCGGRELNLKDYHDIAFEVANCLMAGGYLTRAGREPGKDEEMARRLGRELIKNGASFSVSNE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ISPG_PSEPW
Sequence: MHGESPIKRRESRKIWVGNVPVGGDAPIAVQSMTNTDTNDVAATVGQIQRLVDAGVDIVRVSVPDMDAAEAFGKIKQLVSVPLVADIHFDYKIALRVAELGVDCLRINPGNIGREDRVRAVVDAARDRGIPIRIGVNAGSLEKDLQKKYGEPTPAALVESALRHVEHLDRLDFQDFKVSVKASDVFMAVEAYRLLAKQIIQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEVKVGYDILKSLHLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPLDVAVIGCVVNGPGEAKEAHVGLTGGTPNLIYIDGKPAQKLTNDNLVDELEKLIRQKAAEKVEADAALIARG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: LSPA_ECO55
Sequence: MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSKAKKQ
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS13_THERP
Sequence: MARIAGVDLPRDKRIEYALTLIYGIGWTTARKILERTGIDPWTKVRDLTDDEVQRLRDIIEKEMVVEGDLRRQVAMNIKRLIDIGCYRGLRHRMGLPVRGQRTRTNARTRKGPRPRIGVKKKGKQAGS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y1742_STRPZ
Sequence: MLTFLIPTAKEMMIPKESHPHLLPQDSQAILKIMAAMTTEDLAKSYRIKEEAAKKEQQRWQDMASQQSLAYPAYQLFNGLMYRHIKRDKLTTQEQAYLTQQVYITSSFYGIIPANHPIAEHRHDFHTRIKIEGQSLKSYWRPCYNQFAKEHPQVISLLSSEFDDVFSKDCKQLWISPKFMAEKEGQFKTHSTISKKARGAFLTACMENNCQTVDSLKSLVFAGFYYHPDLSTDHEFVYIKKEA
What are the official names of this protein?
UPF0246 protein Spy49_1742.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: KTHY_METKA
Sequence: MGLYLGVEGIDGVGKSSVVNLAAEFLEIHGLEVTTVREPSTDIGREALEWDDPYLQALAFTLDRMLTLKRVDFEAADVVLSDRTFLSTLAYQSALGADMRWLLELQRPVPKPDVVYIIDREPLAEDATFDKEFLERVRNRYREAARLIEEEFDVEIKWIEAEDMDKEEIAELIVADARRRLDDPLGIPDDLLEG
What are the official names of this protein?
Probable thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: YL876_MIMIV
Sequence: MEKYTVCLCGDCINKKNFLKHCQVIDNNCYIAISNELVDIKFDEYIEHGEFFGEKFYQKSHCIMIDFENILKFNSFMADNKLFTVISHCETPCNYSRFVINYLEYITKNNIINHIKYFLKNDYFNNIRWNCHLREKIFKYSNVSTIRSCLKYLPIEYIGEYFSYSLFRGDNIILDYLVDKIKIYLTSYFTGKKYKGNMFKITNKDKLIDISNIYTRLYNIIYYNKKNENIIEIYNQIINRFQELLESQENINVKKKLIFKHNELKLKLTYNEKVKNRLLGNILVYLNGKPSLIVKQLLMDGVNIHTINRDNGFTFLDYFIKIIIKKKNLDLLDILFEMKLIDQSKLNLILEKSIPPIDFKNDTELEIDKNFIRELSGYGADVDKCFDELIKTAKYYNNNKLVGYLKNLGDDLM
What are the official names of this protein?
Uncharacterized protein L876.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L17x/L18x family.
Protein: INV7_YEASX
Sequence: MLLQAFIFLLAGFAAKISALMTNETSDRPLVHFTPNKGWMNDPNGLWYDAKEGKWHLYFQYNPNDTVWGLPLFWVNMTTGVDNLFYIDKFQVREVK
What are the official names of this protein?
Invertase 7, Beta-fructofuranosidase 7, Saccharase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: YOAV_BACSU
Sequence: MVKVMLGIISVTLIWGYTWVAMKVGIHDIPPLLFSGLRLFIGAVPLFLILFIQRKKLSIQKEHLKSYIIMSLLMGLGYMGILTYGMQFVDSGKTSVLVYTMPIFVTVISHFSLNEKMNVYKTMGLVCGLFGLLFIFGKEMLNIDQSALFGELCVLVAALSWGIANVFSKLQFKHIDIIHMNAWHLMMGAVMLLVFSFIFEAVPSAEWTYQAVWSLLFNGLLSTGFTFVVWFWVLNQIQASKASMALMFVPVLALFFGWLQLHEQITINIILGALLICCGIFMNTFTFSRRKV
What are the official names of this protein?
Uncharacterized transporter YoaV.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VE8E2_HPV58
Sequence: MAILKWKLSRWHTSDQISTTETADPKTTEATNNESTQGTKRRRLDLPDSRDNTQYSTKYTDCAVDSRPRGGGLHSTTNCTYKGRNVCSSKVSPIVHLKGDPNSLKCLRYRLKPFKDLYCNMSSTWHWTSDDKGDKVGIVTVTYTTETQRQLFLNTVKIPPTVQISTGVMSL
What is the function of this protein?
Plays a role in limiting the replication of viral DNA in keratinocytes.  Recruits the host NCoR/SMRT complex to viral replication foci to mediate repression of both viral replication and transcription.
What are the official names of this protein?
Protein E8^E2C.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E8^E2C protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: RL14_METM6
Sequence: MKGLGSTIVRSLPNGARLVCADNTGAKELEVIAVKNYTGTVRRLPAGGVGHMVFVSVKKGTPEMRKQVLPAIIIRQKKEYKRADGTRVKFEDNAAVIVTPEGTPKGSEIKGPVSKEAAERWPGVSRLAKIIH
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SARX_STAA8
Sequence: MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNNDDISKFNALFEDVEQFLNI
What is the function of this protein?
Involved in the regulation of virulence genes.  Acts as a repressor of the agr locus and consequently targets genes regulated by the agr system such as sspA, hla and hlb.  Binds directly to the agr promoter region.
What are the official names of this protein?
HTH-type transcriptional regulator SarX, Staphylococcal accessory regulator X.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_BRUSI
Sequence: MIKSELVQIIASRNPHLFQRDVENIVGAVFDEITNALAEGNRVELRGFGAFSVKNRPARSGRNPRTGETVDVEEKWVPFFKTGKELRDRLNGAV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RAB3B_MESAU
Sequence: MASVTDGKTGVKDASDQNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVPTEKGRLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMSDSLDTDPSVLGASKTTRLSDTPPLLQQNCSC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
Ras-related protein Rab-3B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Note=Colocalizes with GAS8/DRC4 in the Golgi apparatus.
Protein: TUSC_ECOLC
Sequence: MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YERC_BACSU
Sequence: MQIDKLRGKELDQLFNSILSLKDLEECYRFFDDLCTINEIQSLAQRLEVARMLREGNTYHKIETETGASTATISRVKRCLNYGNDAYEMALDRVKETETESSSK
What are the official names of this protein?
Uncharacterized protein YerC.
Protein: ILVC_POLAQ
Sequence: MKVFYDKDADLSLIKGKKVTIIGYGSQGHAHALNLKDSGCNVTVGLRKGGASWSKAENAGLTVKEVGEAVKDADVVMMLLPDEQIADVYNKEVHGNIKQGAALAFAHGFNVHYGQVQPRADLDVIMIAPKAPGHTVRGTYSQGGGVPHLIAVYQDKSGSARDVALSYATANGGGRAGIIETNFREETETDLFGEQAVLCGGAVDLIKTGFEVLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEDTKNAMRQCLKDIQTGEYAKSFILENKAGAPTLISRRRLNAEHEIEIVGAKLRAMMPWIAKNKLVDQTKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.