PharMolix/UniProtQA huggingface dataset:
Protein: RC3H1_XENLA
Sequence: MPVQAPQWTDFLSCPICTQTFDETIRKPISLGCGHTVCKMCLNKLHRKACPFDQTTINTDIELLPVNSALLQLVGAQVPEQQQITLCGGCGAEDTKHYEEARKCVEELALYLKPLSTARGVGLNSTTQSVLSRPMQRKLVTLVHCQLVEEEGRIRAMRAARSLGERTVTELILQHQNPQQLSSNLWAAVRARGCQFLGPAMQEEALKLVLLALEDGSALSRKVLVLFVVQRLEPRFPQASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRTYEALRREHDSQIVQIAMEAGLRIAPDQWSSLLYGDQSHKSHMQSIIDKLQTPASFAQSVQELTIALQRTGDPANLNRLRPHLELLANIDPSPDAPPPTWEQLKDGLVAVKTVVHGLVDYIQNHSKKGTDQQQPPQHSKYKTYMCRDMKQRGGCPRGASCTFAHSQEELEKFRKMNKRLVPRRPLSASLGQLNEVGLPIGAPDEGPMDLPPRKPSGLPNGIVPGSSVTQLISRSTDSGFESVLKPVKLDHLSSSAPGSPPELLDSVPKTSMSALPVNAHPAASRDLPPLPVSKQIQMVPRGSQMYAPPPADTFYQECRGAGPPFDAAPYAQGVYYPPQSSQCVSRFVRPPPAATEPATAYLDHYTPYLQDRVVSTQYGTPTQQYQAIVPTQYQPHYDNRRAYPSNAPPYQREELVRASPVPLEMPPAAVSPYVAESRERYQGIEGYYTHPGQIRPSYHREPYIRLPPQHTAQPHPSLDDLHRRRKEIMAQLEERNVISPPPFAPSPTLPHSFHPEEYLDEELKIPGNFKGNDYSQYSPWSFDTFGPYIGTKDNKSKDVSAGGNVEVANVDGKSLRDQRIELQRRATEPGEDDLIPFGDRPTVSRFGAISRTSKALYQPPGPMQQAMAAHGAAKSSITDYSLYSSHSGLSGPSYPTHQNLPSQGHLSERERLSKPLPTSEREQLRMELQQVNQQISQQAQMRDMEVATNRLLLREASSLGNQQQPPPQQPPAKWPSKVSSKQLSLELHQVEREIGKRTRELSLESHSLSMKSKPDTIKVENGQLDDLPLSFSSEVPNGSGLTQDITLSKTASLTLSEDPQAGGDKSDLMRSGVNSTAAP
What is the function of this protein?
Post-transcriptional repressor.  May recognize and bind to the 3'-UTR of some mRNAs and promote mRNA decay.
What are the official names of this protein?
Roquin-1, RING finger and C3H zinc finger protein 1, RING finger and CCCH-type zinc finger domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasmic granule. Note=During cell stress, localizes to cytosolic stress granules.
Protein: VNPB_CRYNI
Sequence: SGSKTATKGDGCFGVRIDRIGSTSGMGCGGVPKPTPGGS
What is the function of this protein?
Snake venom natriuretic peptide that exhibits hypotensive and vasodepressor activity.  Acts by activating natriuretic receptors (NPR1 and/or NPR2 and/or NPR3) (By similarity).
What are the official names of this protein?
Natriuretic peptide CnNP-b.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOB_LEVBA
Sequence: MAGHLVKYGKHRTRRSYSRIKEVLDLPNLIEIQTNSYNWFLDEGLRDMFDDIMPIEDFQGNLSLEFVDYQLLEPKYSVDEAREHDANYSAPLHVTLRLTNHETGEIKSQDVFFGDFPLMTAQGTFIINGAERVIVSQLVRSPGVYFNEDTDKNGRTVYGATVIPNRGAWLEFETDAKNVSYVRIDRTRKIPMTELVRALGFGSDDEILDILGDNESLMQTLEKDIHKNTDDSRVEESLKDIYERLRPGEPKTADSSRSLLTARFFDPKRYDMAPVGRYKTNKKLSLKTRLLGLTLAETLADPDTGEIIAAKGTVVDKDVMKSLAPFLDQDDFKMVTFQPSDEAVVTEPLKLQIIKVQSPDDPEQEVPVIGNGNIDIKLKHIRPADIIASMNYFFDLQLGIGNTDDIDHLGNRRIRSVGELLQNQFRIGLSRMERVVRERMSIQDAATVTPQQLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINSLSSYARVNKYGFIETPYRRVSWDTHKVTDKIDYLTADEEDNYVVAQANTPLNDDGSFNTDTIMARAQSENIETSADRIDYMDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLLNPHAPLIGTGIEYKAAHDSGVALISQHDGTVEYVDAREIRVRREDGALDTYKLMKFRRSNGGKNYNQRPIVKVGDHVDNDEVLADGPSMENGELALGQNPLVAFMTWQGYNFEDAIGINERLVRDDVYTSIHIEEYESEARDTKLGPEEMTREIPNVGEDALKNLDEDGIIRVGAEVQDGDILVGKVTPKGVTELSAEERLLHAIFGEKAREVRDTSLKVPHGGGGIIQDVKIFTRENGDELSPGVNMMVRVYIAQKRKIQVGDKMSGRHGNKGTVSVVIPEEDMPYMPDGTPIDIMLSPMGVPSRMNIGQVLELHLGMAARKLGVHMATPVFDGAQDTDIADAVKEAGMAADAKTVLYDGRTGEPFDKRVAVGVMHYLKLAHMVDDKMHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKTYEAIVKGDPIPKPGVPESFRVLVKELQSLGLDMKVLNGDKEEIELRDMDDEDDDVVNVDALSKYAQQQEEQRKAAAQTDESKTAPATKNESQPNTQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DHA_STAS1
Sequence: MIIGIPKEIKNNENRVSLSPSGVHALVEQGHTVIVEKSAGLGSYFEDVDYTEAGASIVNEQAEVWNVDMVMKVKEPLEEEFQYFKEGLILFTYLHLANEEKLTRALLENKVVGIAYETVQLPDRTLPLLTPMSEVAGRMSAQIGAEFLQKYKGGMGILLGGVPGVSKGRVSIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQELEDLFDGRVHTIMSNPLNIEQCVKDSDLVIGAVLIPGAKAPNLVTEDMVKEMRDGAVIVDIAIDQGGIFETTDRISTHDDPTYKKHGVVHYAVANMPGAVPRTSTIALNNATLPYAQQLASKGYLKALQDNHALSLGLNTINGELTNKGVAEALNLSYTDIESALK
What is the function of this protein?
Catalyzes the reversible reductive amination of pyruvate to L-alanine.  May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer (By similarity).
What are the official names of this protein?
Alanine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the AlaDH/PNT family.
Protein: RS4_DEIRA
Sequence: MGRFRGSITKQSRREGINLAETEKVQKYLDRRPYGPGQHGQRRKGRPSDYSVRLREKQKLARLYGMNEKQFRNLFEEASNVPGVTGTVFLQLLERRLDNVVFRMGFASTRRQARQFVGHGHILVNGKKVDIASYRVKIGDEISVAEGSRSMGFIQENMDAQKRRRVSPWIEMDQDNFKGTFSRLPAREDLALPINENFIIEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RUVC_PROM5
Sequence: MRIIGIDPGLGRVGYGIIEIQNEKKKFLDCGVIETDKNKKEEDRLYEIFNDLNTLINQWKPDIAAVEKFFFYKSSTTISVVQARGVIMMVLASKNIQVSEYAPSQVKLTIAGSGKASKKEVIEAVMFNLNLNYAPKPDDSADALAIALTKLNEAGIN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: Y019_OSHVF
Sequence: MITCFHSNKNCKTKSIKHSTIILLTMAHIEELTTTDVADALLSELVINHTDLRNKVYEVINDNTSSSLDNLYDVAKALAGSQFIVKKIRIYTKESRKEVWTRLIAGHLPSMIITPFFNAMFPASEIKISTFAEMANKKDLTEEVTIPTLSIVDGFDMKFSEVEHKLISSVLSVCRKVIFINNPAKDYSEQHAERIKLLTCGGKIMTYINRFFMKIKKGVSISAVPLIGDMSLCMLINGLGSSQTNFPPARVSFHITYDVKSRTDMLRIGCGGVISNVFSFDSLGNLTVHKESNKHGYVAIVMDKSLFDKKTSLEINNMMTDVCWEHIEQLKPYPKDYVKVGLLHLESVEFNDQQYYLPVVKRKLPSMFTAVSGRIAGNNFYSMFKDVCLPLPPSSLDGKDVM
What are the official names of this protein?
Uncharacterized protein ORF19.
Protein: AROE_HAEI8
Sequence: MDLYAVWGNPITQSKSPLIQRQLAAQTHQTMEYIAKLGNLDSFEQQLLAFFEEGAKGCNITSPFKERAYQLADEYSQRAKLAEACNTLKKLDDGKLYADNTDGIGLVTDLERLNWLRPNQHVLILGAGGATKGVLLPLLQAQQNIVLANRTFSKTKELAERFQPYGNIQAVSMDSIPLQTYDVVINATSAGLSGGTAPVDVEILKLGLAFYDMQYAKGTDTPFIALCKSLGLTNVSDGFGMLVAQAAHSFHLWRGVMPDFVAVYEQLK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GR32A_DROME
Sequence: MSPNTWVIEMPTQKTRSHPYPRRISPYRPPVLNRDAFSRDAPPMPARNHDHPVFEDIRTILSVLKASGLMPIYEQVSDYEVGPPTKTNEFYSFFVRGVVHALTIFNVYSLFTPISAQLFFSYRETDNVNQWIELLLCILTYTLTVFVCAHNTTSMLRIMNEILQLDEEVRRQFGANLSQNFGFLVKFLVGITACQAYIIVLKIYAVQGEITPTSYILLAFYGIQNGLTATYIVFASALLRIVYIRFHFINQLLNGYTYGQQHRRKEGGARARRQRGDVNPNVNPALMEHFPEDSLFIYRMHNKLLRIYKGINDCCNLILVSFLGYSFYTVTTNCYNLFVQITGKGMVSPNILQWCFAWLCLHVSLLALLSRSCGLTTTEANATSQILARVYAKSKEYQNIIDKFLTKSIKQEVQFTAYGFFAIDNSTLFKIFSAVTTYLVILIQFKQLEDSKVEDPVPEQT
What is the function of this protein?
Gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.  Required for the response to N,N-Diethyl-meta-toluamide (DEET), the most widely used insect repellent worldwide.  Functions as a pheromone receptor for a male inhibitory pheromone and promotes male-male aggression and suppresses male-male courtship.  Also promotes preferentially virgin females courting over mated females.
What are the official names of this protein?
Gustatory and pheromone receptor 32a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr21a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RT08_SCHPO
Sequence: MQLHYVFSHLQNSFRARKSLASVPNCNSVLELCAVLYHQGFLSSIQRGDIHGPDALPTITTRQNVATRRLWLGLKYFEGKPVLHYIRAVSKPSRKVNLTPSELLQFAKGRKVSFVNGLEPAEVGIVETKHGIMSIDDAIKNNLGGNVICRVK
What are the official names of this protein?
37S ribosomal protein subunit S8, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PDXT_FRATW
Sequence: MTQKVGVLAIQGGYQKHADMFKSLGVEVKLVKFNNDFDSIDRLVIPGGESTTLLNLLNKHQIFDKLYNFCSSKPVFGTCAGSIILSKGEGYLNLLDLEVQRNAYGRQVDSFVADISFNDKNITGVFIRAPKFIVVGNQVDILSKYQNSPVLLRQANILVSSFHPELTQDPTIHEYFLAM
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: PYRF_YERPG
Sequence: MTSATKTNNSGSISSPIVVALDYANKDAALAFADQVSPQDCRLKVGKEMFTLYGPELIRDLHQRGFDVFLDLKFHDIPNTTARAVAAAAELGVWMVNVHASGGARMMSAAKEALLPYGAQAPLLIAVTVLTSMDGEDLRDIGITISPAEQAERLAKLTWDCGLDGVVCSAHEAVRLKQVCGEDFSLVTPGIRPQGSEAGDQRRIMTPEQAVAVGVDYMVIGRPITQSPDPEKTLREILASLTKVA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: KTHY_STRT1
Sequence: MSKGLLISIEGPDGAGKTSVLKVLLPRLREVYPAQVITTREPGGVAIAEQIREVILDIDNTAMDAKTELLLYIAARRQHLVEKVLPELENGNMVIMDRFIDSSVAYQGAGRGLDQDEVAWLNNYATDGHKPDLTLLFDVDSETGLARIAANGEREVNRLDLEKLDMHQRVRQGYLDLAEAEPERIKRIDASQTLEEVVEDTWEIIKSYL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SECA_ECO57
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RS12_AZOSB
Sequence: MPTINQLVRKPRQMDVVKSKVPALEACPQKRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQSRSKYGAKRPKKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: STE20_ASPFU
Sequence: MSNDGFSSLKFRRTSSKLQKDPPSVSSRILRSQQSNTSLKRHPSAPVHPRSSVTGSREHSRTRSNAYGSSSSSLEQHSGGPSPVLAGGDSNNSFSSKSRPGRFSFNTDPSSDELTGSPFDSRGMLSALEENTAESEKSPPPQPPTLRSYHTSPDSRGLRQSASFTALQNRMDTFTQKSENDQSTNTKRHSDEANGTKVFGRSKKSSFSSFVNSMLGSPRGIKISAPENPVHVTHVGYDNQTGQFTGLPKEWQRLLQENGISKKEQEEHPQTMVDIMRFYEKNARGDDEVWHKFDHAYAHHQPTANTPGSQRNSPPTSPRFPQNHEGSFENPRAPPPIPRGAPAATQAMSPPIGGLVPSRAPPKPPAPANMIPARPAPQPPVARPPQDAYANQFSTPPISESEPLPSEAQRSRSNSKTNGAQPQWAQPGAIASPAQYQQQQEQAMAAAQQAIVQNQLERSRSQRQQQSRGPEPKQPTQMGHSQHANDHTTALQSPQKAQPVPAARPRQRARQSNAVDVRARLLAICTPGDPTKLYYNLNKIGQGASGGVYTAYQHGTNNCVAIKQMNLDLQPKKELIINEILVMKDSKHKNIVNFLDSYLHGLDLWVVMEYMEGGSLTDVVTFNIMTEGQIAAVCRETLNGLQHLHSKGVIHRDIKSDNILLSLDGNIKLTDFGFCAQINDSQNKRNTMVGTPYWMAPEVVTRKEYGRKVDIWSLGIMAIEMIEGEPPYLTESPLRALYLIATNGTPTIKDEHNLSPVFRDFLHLALKVDPEKRASAHDLLMHPFMSLCSPLTHLAPLVKAARLSRAQEKAQKGGA
What is the function of this protein?
MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle.
What are the official names of this protein?
Serine/threonine-protein kinase ste20.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: LIPB_BURMS
Sequence: MPSAPDAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVEHPPVYTLGQAGNPAHLLVADSGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTLVTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKIAALGLKIRNGCSYHGLSVNVKMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQALEQSND
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_SHIB3
Sequence: MAHRPRWTLSQVAELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPNERDMPYLEQMVQGVKDLGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: SARS_STAAR
Sequence: MKYNNHDKIRDFIIIEAYMFRFKKKVKPEVDMTIKEFILLTYLFHQQENTLPFKKIVSDLCYKQSDLVQHIKVLVKHSYISKVRSKIDERNTYISISEEQREKIAERVTLFDQIIKQFNLADQSESQMIPKDSKEFLNLMMYTMYFKNIIKKHLTLSFVEFTILAIITSQNKNIVLLKDLIETIHHKYPQTVRALNNLKKQGYLIKERSTEDERKILIHMNDAQQDHAEQLLAQVNQLLADKNHLHLVFE
What is the function of this protein?
Transcriptional regulator that controls expression of some virulence factors in a cell density-dependent manner.
What are the official names of this protein?
HTH-type transcriptional regulator SarS, Staphylococcal accessory regulator S.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QVR_DROPS
Sequence: MWKEKGNAIGNWLLAITAIFGFITLIWIPQASAECQTRSIYCYECDSWTDARCKDPFNYTALPRDQPPLMTCNGCCVKMVRHQRSREVVRRMCTSQLQINLFMVDHVCMMESSGNGHMCFCEEDMCNSSKDLYSHGHQLHLIITIAVAVSWLMGQLLNR
What is the function of this protein?
Required for homeostatic regulation of sleep under normal conditions and after sleep deprivation.  Important regulator of the Sh K(+) channel, acting as a signaling molecule that connects sleep drive to lowered membrane excitability, possibly by enhancing K(+) channel activity and thus reducing neuronal excitability (By similarity).
What are the official names of this protein?
Protein quiver, Protein sleepless.
What is the protein family that this protein belongs to?
Belongs to the quiver family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: RS11_FRATT
Sequence: MAKSVRSSKKKVKRVVTDAVAHIYSSFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAADMALEYGVKNVDVLVKGPGSGRDSAVRALNAKNLKVTSITDVTPLPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RS13_PARUW
Sequence: MPRVIGIDIPDNKRLEISLTYLYGIGRHLSNEIIVKLGLDPNMRAHKLTQDDLARLNGLLTSEYMVEGDLRRQVQNNIKRLISIHSYRGMRHRLGLPVRGQRTKTNSRTRKGRRKTVANKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: BIG3_HUMAN
Sequence: MEEILRKLQKEASGSKYKAIKESCTWALETLGGLDTIVKIPPHVLREKCLLPLQLALESKNVKLAQHALAGMQKLLSEERFVSMETDSDEKQLLNQILNAVKVTPSLNEDLQVEVMKVLLCITYTPTFDLNGSAVLKIAEVCIETYISSCHQRSINTAVRATLSQMLSDLTLQLRQRQENTIIENPDVPQDFGNQGSTVESLCDDVVSVLTVLCEKLQAAINDSQQLQLLYLECILSVLSSSSSSMHLHRRFTDLIWKNLCPALIVILGNPIHDKTITSAHTSSTSTSLESDSASPGVSDHGRGSGCSCTAPALSGPVARTIYYIAAELVRLVGSVDSMKPVLQSLYHRVLLYPPPQHRVEAIKIMKEILGSPQRLCDLAGPSSTESESRKRSISKRKSHLDLLKLIMDGMTEACIKGGIEACYAAVSCVCTLLGALDELSQGKGLSEGQVQLLLLRLEELKDGAEWSRDSMEINEADFRWQRRVLSSEHTPWESGNERSLDISISVTTDTGQTTLEGELGQTTPEDHSGNHKNSLKSPAIPEGKETLSKVLETEAVDQPDVVQRSHTVPYPDITNFLSVDCRTRSYGSRYSESNFSVDDQDLSRTEFDSCDQYSMAAEKDSGRSDVSDIGSDNCSLADEEQTPRDCLGHRSLRTAALSLKLLKNQEADQHSARLFIQSLEGLLPRLLSLSNVEEVDTALQNFASTFCSGMMHSPGFDGNSSLSFQMLMNADSLYTAAHCALLLNLKLSHGDYYRKRPTLAPGVMKDFMKQVQTSGVLMVFSQAWIEELYHQVLDRNMLGEAGYWGSPEDNSLPLITMLTDIDGLESSAIGGQLMASAATESPFAQSRRIDDSTVAGVAFARYILVGCWKNLIDTLSTPLTGRMAGSSKGLAFILGAEGIKEQNQKERDAICMSLDGLRKAARLSCALGVAANCASALAQMAAASCVQEEKEEREAQEPSDAITQVKLKVEQKLEQIGKVQGVWLHTAHVLCMEAILSVGLEMGSHNPDCWPHVFRVCEYVGTLEHNHFSDGASQPPLTISQPQKATGSAGLLGDPECEGSPPEHSPEQGRSLSTAPVVQPLSIQDLVREGSRGRASDFRGGSLMSGSSAAKVVLTLSTQADRLFEDATDKLNLMALGGFLYQLKKASQSQLFHSVTDTVDYSLAMPGEVKSTQDRKSALHLFRLGNAMLRIVRSKARPLLHVMRCWSLVAPHLVEAACHKERHVSQKAVSFIHDILTEVLTDWNEPPHFHFNEALFRPFERIMQLELCDEDVQDQVVTSIGELVEVCSTQIQSGWRPLFSALETVHGGNKSEMKEYLVGDYSMGKGQAPVFDVFEAFLNTDNIQVFANAATSYIMCLMKFVKGLGEVDCKEIGDCAPAPGAPSTDLCLPALDYLRRCSQLLAKIYKMPLKPIFLSGRLAGLPRRLQEQSASSEDGIESVLSDFDDDTGLIEVWIILLEQLTAAVSNCPRQHQPPTLDLLFELLRDVTKTPGPGFGIYAVVHLLLPVMSVWLRRSHKDHSYWDMASANFKHAIGLSCELVVEHIQSFLHSDIRYESMINTMLKDLFELLVACVAKPTETISRVGCSCIRYVLVTAGPVFTEEMWRLACCALQDAFSATLKPVKDLLGCFHSGTESFSGEGCQVRVAAPSSSPSAEAEYWRIRAMAQQVFMLDTQCSPKTPNNFDHAQSCQLIIELPPDEKPNGHTKKSVSFREIVVSLLSHQVLLQNLYDILLEEFVKGPSPGEEKTIQVPEAKLAGFLRYISMQNLAVIFDLLLDSYRTAREFDTSPGLKCLLKKVSGIGGAANLYRQSAMSFNIYFHALVCAVLTNQETITAEQVKKVLFEDDERSTDSSQQCSSEDEDIFEETAQVSPPRGKEKRQWRARMPLLSVQPVSNADWVWLVKRLHKLCMELCNNYIQMHLDLENCMEEPPIFKGDPFFILPSFQSESSTPSTGGFSGKETPSEDDRSQSREHMGESLSLKAGGGDLLLPPSPKVEKKDPSRKKEWWENAGNKIYTMAADKTISKLMTEYKKRKQQHNLSAFPKEVKVEKKGEPLGPRGQDSPLLQRPQHLMDQGQMRHSFSAGPELLRQDKRPRSGSTGSSLSVSVRDAEAQIQAWTNMVLTVLNQIQILPDQTFTALQPAVFPCISQLTCHVTDIRVRQAVREWLGRVGRVYDIIV
What is the function of this protein?
Participates in the regulation of systemic glucose homeostasis, where it negatively regulates insulin granule biogenesis in pancreatic islet beta cells (By similarity).  Also regulates glucagon granule production in pancreatic alpha cells (By similarity).  Inhibits nuclear translocation of the transcriptional coregulator PHB2 and may enhance estrogen receptor alpha (ESR1) transcriptional activity in breast cancer cells (PubMed:19496786).
What are the official names of this protein?
Brefeldin A-inhibited guanine nucleotide-exchange protein 3, ARFGEF family member 3.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle membrane; Single- pass membrane protein.
Protein: SFSA_SHEAM
Sequence: MEYPAPLSSAVLITRYKRFLADVTLEDGSQTTLHCPNTGSMKNCLYPGKRVWFSTSDNPKRKYAHTWELAEDDRGNLIGINTARANQLAEEAIGLGQISELQGYNQIRREVKYGNENSRIDLLLSEGQAPDCYIEVKSCTLLDHDWGLFPDAVSTRGQKHLRELMEMKRQGYRAVLLFVVQHQGIHRVAPAEAIDPKYAALLREAIAAGVEVLAYGCMMNNKGLQLNIPIPFHPDAG
What are the official names of this protein?
Sugar fermentation stimulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.
Protein: NDHI_RUMPE
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RS10_THEAB
Sequence: MPGQKIRIRLKAYDHKLLDESAKKIVEIVKQTNAKVSGPIPLPTERTLYVVLRSPLKHKDSREQFEKRIHKRLIDILEPSPKTIDALMKINLPAGVDVEINL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.