PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_I56A2
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSEKGKWTTNTETGAPQLNPIDGPLPEDNEPSGYAQTDCVLEAMAFLEESHPGIFENSCLETMEIVQQTRVDKLTQGRQTYDWTLNRNQPAATALANTIEVFRSNGLTANESGRLIDSLKDVMESMDKEEMEITTHFQRKRRVRDNMTKKMVTQRTIGKKKQRLNKRSYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSIAPIMFSNKMARLGKGYMFESKSMKLRTQIPAEMLASIDLKYFNESTRKKIERIRPLLIDGTASLSPGMMMGMFNMLSTVLGVSILNLGQKRYTKTTYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLVGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFELKKLWEQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDEDYQGRLCNPLNPFVSHKEIESVNNAVVMPAHGPAKSMEYDAVATTHSWIPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEEFAEIMKICSTIEELRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: PLSX_FINM2
Sequence: MKILLDTLGSDKGASELIEGAIMALEKKDFNLTIVGNEEENRNIVNKRFEEKIDFVNATETIENNESPTKAIRSKKDSSMRKCFDLLNEDYDGFLSTGSTGALLTGATLITKRLDNVSRPCLMVTVPSLKGEVVVLDVGANVDVTSDLLEQFAKMGYVYSKNILGKEDCKVGLLNIGVEEHKGDSLRLETYQKLSNYPYFKGNVEARDVLKGDFDVVVTDGFSGNILLKTIEGSVEFIKTLAKSKLSKLDEKSQQIIIPMIKSMSSGIDYNSVGSAPFLGTKKPVFKAHGSSNRNAIMSGILTLIKFIEEDVTDKLKKELTNE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: WECG_SALAR
Sequence: MTNNAAAPLYSLRGLPLIGWRDMPHALNYLFADGQLKQGTLVAINAEKLLTAEDNPDVRALIAAAEFKYADGISVVRSIRKKFPQAQVSRVAGADLWEALMARAGKEGTPVFLIGGKPEVLAQTEEKLRAQWNVNIVGSQDGYFTPEQSQALFARIHASGAQIVTVAMGSPKQEIVMHDCREVHPHALYMGVGGTYDVFTGHVKRAPKIWQNLGLEWLYRLLSQPSRITRQMRLLRYLRWHYTDDL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: LEGA_GOSHI
Sequence: MAINPSLLFLSLLFLFNGCLARQTFSSQQSQNECQINRLRASAPQTRIRSEAGTTEWWNPNCQQLRCAGVSVMRQTIEPNGLVLPSFTNAPQLLYIVQGRGIQGIVMPGCAETFQDSQQWQHQSRGRFQDQHQKVRRFRQGDIIALPQGVVHWSYNDGNERVVTINLLDTGNSANQLDNIPRRFHLAGNPEEEQRQLRRLAQQMQGRSERGEESEEEEGEGEEEEEEDNPSRRSRHQEEEEQGRESSSCNNLLCAFDRNFLAQAFNVDHDIIRKIQRVRGNRGTIIRVRDRLQVVTPPRMEEEEREERQQEQRYRHTRGGSQDNGLEETFCSMRIKENLADPERADIFNPQAGRISTLNRFNLPILQRLELSAERGVLYNRAGLIPQWNVNAHKILYMLRGCARVQVVNHNGDAVFDDNVEQGQLLTVPQNFAFMKQAGNEGAEWISFFTNSEATNTPMAGSVSFMRALPEEVVAASYQVSREDARRIKFNNKNTFFFTPSQSERRADA
What is the function of this protein?
This is a seed storage protein.
What are the official names of this protein?
Legumin A, Beta-globulin, LEGA-C94.
What is the protein family that this protein belongs to?
Belongs to the 11S seed storage protein (globulins) family.
Protein: RL18_ACIBS
Sequence: MNEKKQSRLRRAKSTRLHIRALGVTRLCVNRTPRHIYAQVISADGGKVLAQASTLDASLRSGTTGNIEAATKVGALIAERAKAAGVTKVAFDRSGFKYHGRIKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: HSP1_MYODA
Sequence: MARYRCCRSRSRCRRRRRRCYRRRRRCCRRRRRRRVCCRRYSRCRRR
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex (By similarity).
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS15_WOLWR
Sequence: MSITSEKKKSLINIYAIKEDDTGSSFVQCAILTERISNLTEHFKVHKHDHHSKRGLLILIGRRRKHLNYIKRKFGNEAYQELIEKLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RBL_CHLVU
Sequence: MSPQTETKARVGFKAGVKDYRLTYYTPDYQPKDTDILAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEENQYIAYIAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRGLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEAIYKSQAETGEIKGHYLNATAATAEAMMQRAECAKDLGVPIIMHDYLTGGFTANTSLSHYCRDNGLLLHIHRAMHAVIDRQRNHGITFRVLAKALRLSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDDYIEKDRSRGIYFTQDWVSLPGTMPVASGGIHVWHMPALVEIFGDDACLQFGGGTLGHPWGNAPGAAANRVALEACTQARNEGRDLAREGGDVIRAACKWSPELAAACEVWKEIKFEFETIDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PNCB_SALG2
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVQVAAEFRCRGDDLLGIYADAIREQVDAMQHLRLQEDEFQWLSGLPFFKPDYLNWLREFRYNPAQVCVTNDNGKLNIRLTGPWREVIMWEVPLLAVISELVHHYRSPNAGVDQALDALESKLVDFTALTANLDMSRFHLMDFGTRRRFSREVQQAIVKRLQQESWFVGTSNYDLARRLALTPMGTQAHEWFQAHQQISPDLATSQRAALAAWLNEYPDQLGIALTDCITMDAFLRDFGIEFASRYQGLRHDSGDPVAWGEKAIAHYEKLGIDPLTKTLVFSDNLDLPKAVELYRHFASRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQVRKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: DNLI_NOCFA
Sequence: MLFADVVRTSEAVRATRSRKTKVAALAELLRAAESAELAPVVAWLSGELRQGRIGTGWRTLTGVRVPPALDAALEVATVDAIFDELAAVSGAGSGNRRKELLTRLWSAATEPEQEFLLRLLTGELRQGALTALVAEAVAAAADVPVEQVRRAYMLSGQLPVTAEAALRGGAAALAEFRLEVGRPIQPMLAAPGASLEEAMTEFGGEVSVEHKLDGARIQVHRDGDRIAVFTRTLRDITAGVPELVELVARLDCTSVVLDGETLALTDAGRPRPFQETMSRFATADPARAAEVDLPPGTPVVPPVSSTRELLLHPYFFDCLHLDGRDLLDAPLSERRAALLAVVGEHAIPALIRPEPEAAAEYFDGALAAGHEGLMVKSLSAPYAAGRRGRSWQKIKPTHTLDLLVLGAEWGYGRRTGYLSNLHLGARDPRTGEPVMVGKTFKGLTDALLAWQTAEFPRHERARDEHTVYLWPELVVEIALDGVQVSPRYPGGVALRFARVVRYRPDKTPDQADTIDTVRGLLP
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
Probable DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: HIUH_DEIRA
Sequence: MSGHPGLTTHVLDTARGKPAAGVRVQLCRVTGDTRTPVTEAVTNSDGRTDAPLIERGSLKQGTYELTFHVADYFKGFVAAADPPFLDVVTLRFTVGDTSGHYHVPLVMTPWSYSTYRGS
What is the function of this protein?
Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
What are the official names of this protein?
5-hydroxyisourate hydrolase, HIU hydrolase, HIUHase.
What is the protein family that this protein belongs to?
Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
Protein: CYB5_TOBAC
Sequence: MGGETKVFTLAEVSQHNNAKDCWLVISGKVYDVTKFLDDHPGGDEVLLSATGKDATDDFEDVGHSSSARAMLDEYYVGDIDSATIPTKTKYTPPNQPHYNQDKTSEFVVKLLQFLVPLIILGVAFGIRFYTKQSSA
What is the function of this protein?
Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.  May play a key role in the modification by desaturation of fatty acids in the endoplasmic reticulum, which in the developing seed is utilized for membrane synthesis and in the developmentally regulated production of large amounts of storage lipids.  Is involved in the reduction of cytochrome P-450 and may therefore be involved in flavonoid biosynthesis in the petals.
What are the official names of this protein?
Cytochrome b5.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b5 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: KGUA_STRPD
Sequence: MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQRPGEVDGVDYFFRTREEFEELIKTGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLEIEVQGALQVKSKVPDGVFVFLTPPDLDELEDRLVGRGTDSQEVIAQRIERAKEEIALMREYDYAVVNDEVALAAERVKRIIETEHFRVERVIGRYDKMIKITKNPFKAK
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_YERPE
Sequence: MLYQSETLQLHWLENGIAELVFDAPGSVNKLDTKTVANLGEALNVLEKQSELKGLLLRSAKTALIVGADITEFLSLFNAPPEKLHQWLVFANTIFNRLEDLPVPTISAINGYALGGGCECILATDFRIASPEARIGLPETKLGIMPGFGGSVRLPRLLGADSALEIIATGKDVTANDALKIGLVDAVVDPEKLVGSALTMLKQAIDGKLDWQAARRPKLEPLKLNPTEAAMCFTIAKGRVMQVAGKHYPAPLTAVKTIEAAAKFGRTEALNLETNSFVPLAGSNEARALVGIFLNDQYVKAQAKKLSKGVAAPKLAAVLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNKQLERGKVDGLKMASILATIRPTLDYAGIERAQVIVEAVVENPKVKAAVLAEVEALIGEDTVLASNTSTIPIDQLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQMGKTPIVVNDCPGFFVNRVLFPYLAGFGMLVRDGGDFHQIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPERMNKDYRDAVDVMFDNQRFGQKNGQGFYRYTQDAKGKPRKENDEQVDKLLAEISQPLQEFSDEDIIARTMIPMINEVVRCLEEGIIASAAEGDMALVYGLGFPPFHGGVFRYLDTLGSANYVEMAQRYAHLGALYHVPAGLRAKAEHNESYYPVAAALLDVSTNQPA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: IKBL1_PANTR
Sequence: MSNPSPQVPEEEASTSVCRPKSSMASTSRRQRRERRFRRYLSAGRLVRAQALLQRHPGLDVDAGQPPPLHRACARHDAPALCLLLRLGADPAHQDRHGDTALHAAARQGPDAYTDFFLPLLSRCPSAMGIKNKDGETPGQILGWGPPWDSAEEEEDDASKEREWRQKLQGELEDEWQEVMGRFEGDASHETQEPESFSAWSDRLAREHAQKYQQQQREAEGSCRPPRAEGSSQSWRQQEEEQRLFRERARAKEEELRESRARRAQEALGDREPKPTRAGPREEHPRGAGRGSLWRFGDVPWPCPGGGDPEAMAAALVARGPPLEEQGALRRYLRVQQVRWHPDRFLQRFRSQIETWELGRVMGAVTALSQALNRHAEALK
What is the function of this protein?
Involved in the regulation of innate immune response.  Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways.  Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (By similarity).
What are the official names of this protein?
NF-kappa-B inhibitor-like protein 1, Inhibitor of kappa B-like protein, I-kappa-B-like protein, IkappaBL, Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1.
What are the subcellular locations of this protein?
Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with CACTIN in the nucleus (By similarity).
Protein: MIAA_CERSK
Sequence: MAEDAQGRPAPTSPFFVTIPSKLLPQLPDIPSDRPVLIAGPTASGKSALAVRLVEDGGGVVVNADALQVYDCWRILSARPSAAEEAALPHRLYGHVGARQTYSAGHWLKEVAAVLAEGLRPVIVGGTGLYFSALTEGLAEIPHTPPEVRAEADARLAEAGLARMVAELDAETAARIDLQNPARVQRAWEVLRATGRGLARWQAETAPPLLPLSDATALVIRPDPTWLAQRIDSRFNLMMADGALEEVRAALPGWDPTLPSARAIGAPELVAHLRGEIPLDEAVAAAKLASRQYAKRQRTWFRNRMRLWHEIRLP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RAVR1_HUMAN
Sequence: MAADVSVTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGSGLRGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKVRAGGGDMQGWEAPAPQRPLTRPALPSVSRPHWAARNAALPTCCPRPSPAQKAAMWASTPRASAATTRTPT
What is the function of this protein?
Cooperates with PTBP1 to modulate regulated alternative splicing events.  Promotes exon skipping.  Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
What are the official names of this protein?
Ribonucleoprotein PTB-binding 1, Protein raver-1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear, in perinucleolar structures. Shuttles between nucleus and cytoplasm. Cytoplasm, at focal contacts and cell-cell contacts. Associated with myotubes during muscle differentiation (By similarity).
Protein: TMM47_DANRE
Sequence: MASSVSGAEEVRVSALTPLKLVGLVCVFLALCLDVGAVLSPAWVTADDQYHLSLWKSCSKPAASATWRCNSTLGTDWQIATLALLLGGAFLILLSFLVALVSVCIRSRRRFYRPVAIMLFAAVVLQACCLVLYPIKFIETISLRIYHEFNWGYGLAWGATIFSFGGAILYCLNPKNYEDYY
What is the function of this protein?
Regulates cell junction organization in epithelial cells.
What are the official names of this protein?
Transmembrane protein 47, Transmembrane 4 superfamily member 10.
What is the protein family that this protein belongs to?
Belongs to the TMEM47 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell junction, adherens junction.
Protein: EFTU_SOLUE
Sequence: MAKEKFDRSKPHVNIGTIGHIDHGKTTLTAAITKVLAKHNPKNKFRSFDSIDNAPEEKARGITIAVAHVEYETAKRHYAHVDCPGHADYIKNMITGAAQMDGAIVVVAATDGPMPQTREHILLARQVGVPYIVVAMNKVDMVDDSELLDLVELEVRELLKSYQFPGDDLPVVRVSALGALNGEPQWEKTVDELMEAVDSYIPMPERAIDKPFIMPIEDIFSIQGRGTVVTGRIERGICKVGEEMEIVGFRDTRKTVVTGVEMFKKLLDEGRAGDNVGLLLRGVEKDMVERGQVIAKPGSITPHTKFKGEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGVAQLPEGTEMVMPGDNVSLEVELITPVAMDKGLRFAIREGGRTVGAGTVTEILK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y439_METC4
Sequence: MRPPADPGARRRATHGRGLSAEGLALLVLMLKGYRPLARRFAAAGGEIDLIVRRGRTIAFVEVKARATLDAAATAIDARKRARVSRAARAWLARHPLAADTTLRADAVFVAPRRWPRHLPNAFEIEGL
What are the official names of this protein?
UPF0102 protein Mchl_0439.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: CTAA_STAHJ
Sequence: MFNKRNLKWLSVLATIIMAFVQLGGALVTKTGSEDGCGSSWPLCHGALLPQNLPIDTIIELSHRAVSGLSLIVVLWLAITAWKHIGYIREVKPLAIISIAFLLVQALIGAAAVIWQQNSYVLALHFGISLISFSSVFVLMLIIFEVDKKYEADELYIRKPLRRLTWIMTGIVYLTIYTGALVRHAKASLAYGGWPLPFHDIIPHTEQDWVQFAHRGMAFITFFWIMITFIHAVKNYSENRTIRYGYTTAFILIILQVITGALSVMTNVNLFIALLHALFITILFGMIAYFIMLMLRTIRSEKIK
What is the function of this protein?
Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8.  The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.
What are the official names of this protein?
Heme A synthase, HAS, Cytochrome aa3-controlling protein.
What is the protein family that this protein belongs to?
Belongs to the COX15/CtaA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRP28_KLULA
Sequence: MLRPVSIDDLISDTVPAKKPRFLIKKRTFPQPEEEEASKALSHTVIKRKDNYRNLDEDELYEEQVSNEPDDLLFLARKSADLLKKRQNEDESIVDNYLGKHWSEKKYEEMSTRDWRILSEDFNISSKGGTVEKPLRNWHELKLIPEDLLNIITNDLHYNEPTSIQRSTIPNVINNRDFIGVASTGSGKTLAFLLPILIKLHGIPPLNSITKHDGPLALVLAPTRELAQQIQHEGQSITKLWKRPCNIVSIVGGHSLEEISANLRDGCDILVATPGRLLDCLDSHLLFLKQVNTLVLDEADKMIDFGFEDQLTTILAKTETISNRQTMMFTATFSPTIEKVANGYLKKPSYVTVGGEESKPKIKQIVRYVPDEEEKLKILVKDFLPNYKAPIIIFINYKRTADWLFDKLREARFRATTLHGSKSQEQREHSLSLLRNGKVDILIATDVAGRGIDIPNVSLVVNLQFPKSFDSFVHRVGRTGRAGKTGTALTFLTEEEDHSAMAKLFDYVKKNDFTGENYISKEAMSKYNVDKSSYKPIII
What is the function of this protein?
ATP-dependent RNA helicase involved in mRNA splicing.  May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site.  May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX23/PRP28 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RRF_XANOM
Sequence: MLTQIKQDAQTRMTKSIDALRHSLTTVRTGRASPALLDGIKVKAYGTDTPLNQVASISVSEGRSLVISLFDKGMIKDVEKAIYASDLGLTPTVVGTVIRLNLPPLTEERRKELSKSVHGEGEDSKVAIRNIRRDANQQVKDLLKDKAVTEDEARGAEDDIQKLTDKAIKDVDEVVKAKEQELMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_PROM0
Sequence: MFEFEITSDCINTGARTGIFHTPNGKVNTPKFMPVGTLATVKGISSKQLISTGSEMILSNTFHLHLQPGEKLVKASGGIHKFMNWPKPILTDSGGYQVFSLAKLNNISDEGVEFKNPRDGSHVFLSPEKVIKIQMDLGSDVAMAFDHCPPHTANENDIEDSLERTHSWLQKCVETHQKSNQALFGIVQGGKYPRLREYSAKYTSSFDLPGIAVGGVSVGEAVEEIHSVINYVPKFLPINKPRYLMGIGSLKEISLAVANGFDIFDCVLPTRLGRHGTAFFNDERLNLRNARFKNDFSPIDKTCKCETCKSYSRAYLHHLIRNDEILGLSLISLHNIAHLIRFTNAISTAIRDNCFTNDFAPWKTSSIAHHTW
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: UPPS_ECOL6
Sequence: MMLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEKVQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTEPGDETA
What is the function of this protein?
Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP).  UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
What are the official names of this protein?
Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), Ditrans,polycis-undecaprenylcistransferase, Undecaprenyl diphosphate synthase, UDS, Undecaprenyl pyrophosphate synthase, UPP synthase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: RSMH_XANOP
Sequence: MSQPPAAHVPVLYTQVLDGLQVTENGTYLDGTFGRGGHARGVLEHLGPGGRLLVMDKDPDAIAVAEQTFGGDARVSIHRGSFAGLGQVVAAATVDGILLDLGVSSPQLDVAGRGFSFGKDGPLDMRMDPDSGQSAAQWLAQATDREIADVLWAYGEERQSRRIARAIVARRAEQPLLRTAQLADLIASVMPRGDSKTHPATRSFQAIRIYINRELDDLETGLDAALAALKPGGRLAVISFHSLEDRIVKQFMARYAKAPPSNRRLPEAQPFVPTLQLVSGAIKADDTELNVNPRARSAVLRVAEKLELGIGDSGLERRSGRIPNPRSPIPASQGDAR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.