PharMolix/UniProtQA huggingface dataset:
Protein: VP35L_PONAB
Sequence: MAVFPWHSRNRNYKAEFASCRLEAVPLEFGDYHPLKPITVTESKTKKVNRKGSTSSTSSSSSSSVVDPLSSVLDGTDPLSMFAATADPAALAAATDSSRKKRDRDDNSIVGSDFEPWANKRGEILARYTTTEKLSINLFMGSEKGKAGTATLAMSEKVRTRLEELDDFEEGSQKELLNLTQQDYVNRIEELNQSLKDAWASDQKVKALKIVIQCSKLPSDTSVIQFYPSKFVLITDILDTFGKLVYERIFSMCVDNRSVLPDHFSPENANDTAKETCLNWFFKIASIRELIPRFYVEASILKCNKFLSKTGISECLPRLTCMIRGIGDPLVSVYARAYLCRVGMEVAPHLKETLNKNFFDFLLTFKQIHGDTVQNQLVVQGVELPSYLPLYPPAMDWIFQCISYHAPEALLTEMMERCKKLGNNALLLNSVMSAFRAEFIATRSMDFIGMIKECDESGFPKHLLFRSLGLNLALADPPESDRLQILNEAWKVITKLKNPQDYINCAEVWVEYTCKHFTKREVNTVLADVIKHMTPDRAFEDSYPQLQLIIKKVIAHFHDFSVLLSVEKFLPFLDMFQKESVRVEVCKCIMDAFIKHQQEPTKDPVILNALLHVCKTMHDSVNALTLEDEKRMLSYLINGFIKMVSFGRDFEQQLSFYVESRSMFCNLEPVLVQLIHSVNRLAMETRKVMKGNHSRKTAAFVRACVAYCFITIPSLVGIFTRLNLYLHSGQVALANQCLSQADAFFKAAISLVPEVPKMINIDGKMRPSESFLLEFLCNFFSTLLIVPDHPEHGVLFLVRELLNVIQDYTWEDNSDEKIRIYTCVLHLLSAMSQETYLYHIDKVDSNDSLYGGDSKFLAENNKLCETVMAQILEHLKTLAKDEALKRQSSLGLSFFNSILAHGDLRNNKLNQLSVNLWHLAQRHGCADTRTMVKTLEYIKKQSKQPDMTHLTELALRLPLQTRT
What is the function of this protein?
Acts as component of the retriever complex.  The retriever complex is a heterotrimeric complex related to retromer cargo-selective complex (CSC) and essential for retromer-independent retrieval and recycling of numerous cargos such as integrin alpha-5/beta-1 (ITGA5:ITGB1).  The recruitment of the retriever complex to the endosomal membrane involves CCC and WASH complexes.  In the endosomes, drives the retrieval and recycling of NxxY-motif-containing cargo proteins by coupling to SNX17, a cargo essential for the homeostatic maintenance of numerous cell surface proteins associated with processes that include cell migration, cell adhesion, nutrient supply and cell signaling.  Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association with the CCC complex and cooperation with the WASH complex on early endosomes.  Seems not to be required for CCC complex stability.
What are the official names of this protein?
VPS35 endosomal protein-sorting factor-like.
What is the protein family that this protein belongs to?
Belongs to the VPS35L family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Endosome. Note=Endosome location is dependent of the association with the CCC and WASH complexes.
Protein: PAI2_ARATH
Sequence: MSTGISTDLHVHFGALNFSKTYKSGLSNRTVSFSRVGYAQNRKLSCSVSNTENVAPKDDERGKDRPLVKMCGITSARDAAMAVEAGADFIGMIIWPHSKRSISLSVAKDISKVAREGGAKPVGVFVEDDDNTILRAADSSDLELVQLHGNGSRAAFSRLVRKRRVIYVLNANQDGKLLNEVPEEDCHLADWILVDSATGGSGHGFNWAQFKLPSVRSRNGWLLAGGINPTNVSEALSILQPDGIDVSSGICGTDGIQKDKSKISSFITAVRSVHY
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase 2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLPB_HAES1
Sequence: MKFDVVIIGGGLAGLTCGIMLQQKGKCCAIINNGQSAMNFSSGSMDLLSQLPNGEKINSFEQGYDSLEEQLPNHPYCLFGKQHVLQKAKQFEQLIEKINLNVTGSYKQNHFRVTPLGGLHRTWLSADCIPTMDLHDEHFGYQKITVLGIEGYHDFQPHLLAENLIQHPQFTHCSITTALLHLPELDQLRLTSREFRSVNISQLLEHRLAFRELVQEIKQASGDGEAIFLPACFGLDNQDFFNKLTLETGLNLYELPTLPPSLVGLRQHKKLKTYFEKLGGFILNGDKALRAVIEDQQVKQIYTQLHQEHGIFAEHFVLASGSFFSNGLVSVFDRLLEPIFDVDMIGNSMIDIQNRLTWTARRFSSPQPYQSAGVAINSCCQLKKSGQIIKNLYAAGNVIGGYNALELGCGSGVAVVTALTVADNIIEAQNRV
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.
Protein: DEGS_ECOLI
Sequence: MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYPATN
What is the function of this protein?
A site-1 protease (S1P) that cleaves the peptide bond between 'Val-148' and 'Ser-149' in RseA.  Part of a regulated intramembrane proteolysis (RIP) cascade.  When heat shock or other environmental stresses disrupt protein folding in the periplasm, DegS senses the accumulation of unassembled outer membrane porins (OMP) and then initiates RseA (anti sigma-E factor) degradation by cleaving its periplasmic domain, making it a substrate for subsequent cleavage by RseP.  This cascade ultimately leads to the sigma-E-driven expression of a variety of factors dealing with folding stress in the periplasm and OMP assembly.  Required for basal and stress-induced degradation of RseA.
What are the official names of this protein?
Serine endoprotease DegS, Site-1 protease DegS, S1P protease DegS, Site-1-type intramembrane protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=It is unclear how this protein is anchored to the inner membrane, programs predict a signal sequence, but replacing the N-terminal 26 residues with a known signal sequence gives a protein unable to fully complement a disruption mutant.
Protein: BCAT2_HUMAN
Sequence: MAAAALGQIWARKLLSVPWLLCGPRRYASSSFKAADLQLEMTQKPHKKPGPGEPLVFGKTFTDHMLMVEWNDKGWGQPRIQPFQNLTLHPASSSLHYSLQLFEGMKAFKGKDQQVRLFRPWLNMDRMLRSAMRLCLPSFDKLELLECIRRLIEVDKDWVPDAAGTSLYVRPVLIGNEPSLGVSQPTRALLFVILCPVGAYFPGGSVTPVSLLADPAFIRAWVGGVGNYKLGGNYGPTVLVQQEALKRGCEQVLWLYGPDHQLTEVGTMNIFVYWTHEDGVLELVTPPLNGVILPGVVRQSLLDMAQTWGEFRVVERTITMKQLLRALEEGRVREVFGSGTACQVCPVHRILYKDRNLHIPTMENGPELILRFQKELKEIQYGIRAHEWMFPV
What is the function of this protein?
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine (PubMed:8702755, PubMed:25653144, PubMed:17050531).  May also function as a transporter of branched chain alpha-keto acids (By similarity).
What are the official names of this protein?
Branched-chain-amino-acid aminotransferase, mitochondrial, BCAT(m), Placental protein 18, PP18.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MURA_ERWT9
Sequence: MDKFRVQGPTRLSGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDIDTTMKLLSQLGVKAERNGSVYLDASKVDIYCAPYELVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHITGLEQLGAEIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMSAATLATGTTVIENAAREPEIVDTANFLNTLGAKISGAGSDRITIEGVERLGGGVYRVLPDRIETGTFLVAGAISGGKVICRAAQPDTLDAVLAKLREAGAEIEVGDDWVSLDMHGKRPKAVSLRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELARMGAHAEIESHTLICHGVEKLSSAQVMATDLRASASLVLAGCIAEGVTVVDRIYHIDRGYEHIEDKLIALGANIQRISGEE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIM_CLOTE
Sequence: MKKNLTFFMVIALLFTITPNVYAMHIAEGFLPPMWSGVYFVISAPFIIIGLKQIRERAKDNKDIKMLLGLVAAYAFILSAMKIPSVTGSCSHPTGTGLSAIIFGPFISAIVGLIVLIFQAILLAHGGITTLGANTLSMGIMGPIVSYLIYRGFKNKNQKVAVFLAATLGDLFTYFITSVQLALAFPAQQGGIAASFAKFFSIFSITQIPLAIMEGILTVIIFEFVMKYASKEIEVLGGVRK
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRUA_SHISS
Sequence: MSDQQQLPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPERWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GLRX_PSEAE
Sequence: MPPVVIYTTAWCPYCIRAKQLLQRKGVDFQEIACDGKPELRAELARKAGSTTVPQIWIGETHVGGCDDLHALERAGKLDALLSA
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Glutaredoxin.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_NEIM0
Sequence: MSVTVETLENLERKVVLSLPWSEINAETDKKLKQTQRRAKIDGFRPGKAPLKMIAQMYGASAQNDVINELVQRRFHDVAVAQELKVAGFPRFEGVEEQDDKESFKVAAIFEVFPEVVIGDLSAQEVEKVTASVGDAEVDQTVEILRKQRTRFNHVEREARNGDRVIIDFEGKIDGEPFAGGASKNYAFVLGASQMLPEFEAGVVGMKAGESKDVTVNFPEDYHGKDVAGKTAVFTITLNNVSEATLPEVDADFAKALGIADGDVAKMREEVQKNVSREVERRVNEQTKESVMNALLKAVELKAPVALVNEEAARLANEMKQNFVNQGMADAANLDLPLDMFKEQAERRVSLGLILAKLVDENKLEPTEEQIKAVVANFAESYEDPQEVIDWYYADPSRLQAPTSLAVESNVVDFVLGKAKVNEKALSFDEVMGAQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HAS1_MAGO7
Sequence: MDDRSSKKRKLKDVNGAKASGAATDVTVKPKKLKKAQSQEEVEPKVEKGSKKEEEENDWSDEEENEAADDAGHSSDSDVDEGDDTIAAPAKEADGDIPGDLTLPTTAESEAQAFSELNLSENTMKAIEEMGFTKMTEIQRRGIPPLLAGKDVLGAAKTGSGKTLAFLIPAVEMLRSLKFKPRNGTGVIVVSPTRELALQIFGVARDLMKHHSQTYGIVIGGANRRAEAEKLSKGVNLLIATPGRLLDHLQNTPFVFKNLRSLVIDEADRILEIGFEDEMRQIIKILPKERQSMLFSATQTTKVEDLARVSLRPGPLYLNVDEEKEYSTVEGLEQGYVVCEADKRFILLFSFLQKMKKKKIIVFFSSCNSVKYYAELLNYIDCQVLDLHGKQKQQKRTNTFFEFCNADRGTLICTDVAARGLDIPAVDWIVQFDPPDDPRDYIHRVGRTARGTNKKGRSLMFLLPSEVGFLTYLKQARVPVVEFDFPTKSIKNVQSQLEKLIGKNYYLNSSAKDGFRSYLHAYASHSLRSVFDINKLDLAKVAKSFGFATPPRVDIQLGASMSKDKKAGGRRAYGSQPRQGGTYGKRR
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: THII_BACP2
Sequence: MKYDHILVRFGEISTKGKNRKKFIEKLRQHIRFVLKDFVALKYASDRDRITIMLNGEDPEPISEQLKGVFGIQSFSLAVKCETNLDAIKEAALTAVQEVYEQGNTFKVSTKRSYKQFELDSNEMNREIGGHVLRNTENLTVNVKQPDVHLRIEIREQATYITFKDVKGAGGLPVGSSGRAMLMLSGGFDSPVAGYQAMKRGIQIEAVHFFSPPYTSERAKQKVIDLTECLAAYGGEIKLHIVPFTKIQELIHKQVPENYTMTSTRRMMLKIADKIREKRDALAIITGESLGQVASQTLESMYAINHVTNTPIIRPLIAVDKNDIIDEARRIGTYETSIQPFEDCCTIFTPPSPKTKPKLEKVERYESFADFEPMLDEAVEQIETIIVKNEKKAADEFADLF
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_STAAS
Sequence: MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMGIMFIGVGLVEALPIIGVVIAFMTFAG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSUG_DEIRA
Sequence: MTSKPSNDRLHSYLDLQPEVAAALSQGRPVVALESTIISHGMPYPQNVEMARGVEQIVRDNGAVPATIAVLGGRLKVGLSADELELLATDKAVQKISTRDLPVTVALGGHGATTVASTMRIAALAGIRVFATGGTGGVHRGAGETMDISADLLELARTDVCVVSAGVKSILDIGLTLEVLETQGVPAITLGADEFPAFYSRRSGFSSPLTVQTPAEAARVLKVKWDLGLTGGVLLANPVPETAEIPAEEMETHITRALADMAALGLSGKDTTPYLLGRIVELTGGRSLETNIALVRHNAAAAAQVAAEYARLG
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: TIG_ANADF
Sequence: MKIQVENVSPVERKVSIEVDPDRVAQELERAYAGLGRRVKLRGFRPGKAPRKVLERQFRAEVESEVLEKIVQQTFAEAVKVESLPLVAPPHVSVSEGVADGKPIRYTARVEVKPAIAPKDYRGLEVTRKAPEVTDQMVSDELSRLQDSLAQLVPVEGRFEAQEDDWAVIDHEGTIDGKPFEGGKAEGVTVKVAPGAISDGNLEALKGKKLGETVELDEPFPEDHRVEQLRGKTAHMKVTLKALKTRQLPALDDALAKEAGVEGIETLDALRARIRADLEKREKRRAESEVKDALVKAALAKNEFEVPPALVERAIDSMLEGAAERFARSGIDIRRLELDFAKMRADMREQALLQVRGALLLEAIADAEKIEVTDEDLQAEAARIAEELGAPLAKVQQQMRGKDAREALKNKVREDKALALLSSAANIQPA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: MBR1_YEAS6
Sequence: MRMEKTTDKPLSAGDMNDEYSRGPIDDIDCLNFFERAVQDPCCEACDTEDADEELRAKLSSFNFQPDSSPCNAKCQQTLNPLCKIDEGLPAESELAPSRNGSVSEANSDTNSIASTVHDPVDSKYGGMPSLRKAKTTSYFTSSSSNNTTMRNPLKKCNTNINGLLVNRRSSSSSRQSIPELFSGACTKKKNNVLLKSETPNSEFSTNSLQHCNSRSFSLPRSRSRSSAIAIPTHLYGLEKYVSPELDTLTADPEESIERFSNNRPREISSCCPNDTGDTSSSLSHSNTSSSLNFPLGTNTNQFHQPRQPVQQQQSSKPNFGAGRKKSFIEMSLASSFAG
What is the function of this protein?
Participates in mitochondrial biogenesis and stress response.
What are the official names of this protein?
Mitochondrial biogenesis regulation protein 1.
What is the protein family that this protein belongs to?
Belongs to the ISF1/MBR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PSS_HELPJ
Sequence: MPINPLYLFPNLFTASSIFLGMMSIFYASSYQFVMACWLVVASLILDGLDGRVARLTNTTSKFGIEFDSLADVVAFGVAPSLITYFYVGYNFGRIGMAVSALFVIFGAIRLARFNISTNTSDPYSFIGIPIPAAAVLVVLCVLLDNKYHFLEGNTEKLFLGFIVLLGVLMVSNIRYPNFKKVKWNLKLFILVLIFLSLVFVRPLEALSVFMGLYLIYGIIRWIFLMVKIIFNKNKSA
What are the official names of this protein?
CDP-diacylglycerol--serine O-phosphatidyltransferase, Phosphatidylserine synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LSI2_ORYSJ
Sequence: MSELASAPKVALGSIAFAVFWMMAVFPSVPFLPIGRTAGSLLSAVLMVIFHVISPDDAYASIDLPILGLLFATMVVGSYLRNAGMFKHLGRLLAWKSQGGRDLMCRVCVVTALASALFTNDTCCVVLTEFVLELAAERNLPAKPFLLALASSANIGSAATPIGNPQNLVIAFNSKITFPKFLMGILPAMLVGMAVNMVMLLCMYWRELGGGAELSVDGKQMEAVEEGRSPASAKSTPQLNGNGNTMMSLEMSENITTKHPWFMQCTEARRKLFLKSFAYVVTVGMVVAYMVGLNMSWTAITTALALVVVDFRDAEPCLDTVSYSLLVFFSGMFITVSGFNKTGLPGAIWDFMAPYSKVNSVGGISVLSVIILLLSNLASNVPTVLLMGDEVAKAAALISPAAVTTSWLLLAWVSTVAGNLSLLGSAANLIVCEQARRAPRNAYDLTFWQHIVFGVPSTLIVTAVGIPLIGKI
What is the function of this protein?
Silicon efflux transporter involved in silicon transport from the root cells to the apoplast.  Is coupled with the silicon influx transporter NIP2-1/LSI1 in both exodermal and endodermal root cells for an efficient silicon transport across the cells into the stele.  Silicon is beneficial to plant growth and helps plants to overcome abiotic and biotic stresses by preventing lodging (falling over) and increasing resistance to pests and diseases, as well as other stresses (PubMed:17625566).  In the nodes, involved with LSI3 and NIP2-2/LSI6 in silicon intervascular transfer, which is required for the preferential distribution of silicon, such as hyperaccumulation of silicon in the husk (PubMed:26283388).  Is coupled with NIP2-1/LSI1 transporter in roots for efficient uptake of arsenite, which is further dispatched in shoots and grains (PubMed:18626020).
What are the official names of this protein?
Silicon efflux transporter LSI2, Low silicon protein 2.
What is the protein family that this protein belongs to?
Belongs to the arsenite-antimonite (ArsB) efflux (TC 2.A.45) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR5_BARHE
Sequence: MNNQDLINDKSKNGLTYAKAGVNIDMGNAMVEKIKPFIRATKRAGTDAEIGGFGGLFDLKAAGFTDPILVAANDGVGTKLKIAIEVGIHDTIGIDLVAMCVNDLLVQGAEPLFFLDYFATGKLDPEQGAAIVSGIAKGCQQAGAALIGGETAEMPDMYAKGDYDLAGFAVGAAERSALLPSKDLTEGDIILGLSSSGIHSNGFSLVRRIIQQSDLKWNDHAPFNPQMNLGTALLTPTRIYVKSLLPIIKSYKGIKALAHITGGGFLENIPRVLPSSLCAEINLSAIHVPSIFSWIAKQGKIEKIEMLRTFNCGVGMIIIVAQHEVEKVTQELKMQGETVTLLGKLTKRQNKGITFKGALHL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCMO_POPTM
Sequence: MDLLLLEKTLLGSFVAILVAILVSKLRGKRFKLPPGPLPVPVFGNWLQVGDDLNHRNLTDLAKKFGDILLLRMGQRNLVVVSSPELSKEVLHTQGVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRYGWEEEAAQVVEDVKKNPGAATHGIVLRRRLQLMMYNNMYRIMFDRRFESEEDPLFNKLKALNGERSRLAQSFDYNYGDFIPILRPFLRGYLKICQEVKERRLQLFKDYFVDERKKLASTKNMCNEGLKCAIDHILDAQKKGEINEDNVLYIVENINVAAIETTLWSIEWGIAELVNHPEIQKKLRHELDTLLGPGHQITEPDTYKLPYLNAVVKETLRLRMAIPLLVPHMNLHDAKLGGFDIPAESKILVNAWWLANNPAHWKNPEEFRPERFLEEEAKVEANGNDFRYLPFGVGRRSCPGIILALPILGITLGRLVQNFELLPPPGQSKIDTSEKGGQFSLHILKHSTIVAKPRSF
What is the function of this protein?
Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate (By similarity).  The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens (By similarity).
What are the official names of this protein?
Trans-cinnamate 4-monooxygenase, Cinnamic acid 4-hydroxylase, C4H, CA4H, Cytochrome P450 73, Cytochrome P450C4H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ROT1_SCHPO
Sequence: MHLLYQIGLFTCLWLTQYVGAEIDNYDENLVGTWSSKSETVLTGPDFFDPLDEDFFEPELPGISYSFTDDGFFEEAIYIIKSNATKPQCPKGFLQWQHGTYAINDTGTLVLTPFVGDGRQLESDPCTSNFSVYTRYDQVETMEKYEISMDRYHGRYKLELYEWDGTPKQPMFLAYRPPKMLPTSTIAVNTIQTAAKRWTAPLVPLAQKHTNTIWWVGLGLIAIGSIGYLVVS
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
What are the official names of this protein?
Protein rot1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: CH60A_ARATH
Sequence: MYRFASNLASKARIAQNARQVSSRMSWSRNYAAKEIKFGVEARALMLKGVEDLADAVKVTMGPKGRNVVIEQSWGAPKVTKDGVTVAKSIEFKDKIKNVGASLVKQVANATNDVAGDGTTCATVLTRAIFAEGCKSVAAGMNAMDLRRGISMAVDAVVTNLKSKARMISTSEEIAQVGTISANGEREIGELIAKAMEKVGKEGVITIQDGKTLFNELEVVEGMKLDRGYTSPYFITNQKTQKCELDDPLILIHEKKISSINSIVKVLELALKRQRPLLIVSEDVESDALATLILNKLRAGIKVCAIKAPGFGENRKANLQDLAALTGGEVITDELGMNLEKVDLSMLGTCKKVTVSKDDTVILDGAGDKKGIEERCEQIRSAIELSTSDYDKEKLQERLAKLSGGVAVLKIGGASEAEVGEKKDRVTDALNATKAAVEEGILPGGGVALLYAARELEKLPTANFDQKIGVQIIQNALKTPVYTIASNAGVEGAVIVGKLLEQDNPDLGYDAAKGEYVDMVKAGIIDPLKVIRTALVDAASVSSLLTTTEAVVVDLPKDESESGAAGAGMGGMGGMDY
What is the function of this protein?
Implicated in mitochondrial protein import and macromolecular assembly.  May facilitate the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
What are the official names of this protein?
Chaperonin CPN60, mitochondrial, HSP60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TXND9_CAEEL
Sequence: MAANIQQQFGEQLLRAAQVVEEQIDQEMNKLENLEEDDLEVIRRQRMEQMKKAQKDRIEMLSHGHGKYEEVADEKEFFEATKKSDKVVCLFYLPGNFRCKIVDKHFEILARKHVGTRFIHVNAEKVHFLTTRLNIRVIPSIAIVVKQQTVDYIRGFDELGGKDEFTTETMENRLARSEVLTVEKKHTAPAKKKIIRSGVEEYDNEEDW
What is the function of this protein?
Required for normal microtubule organization and function (PubMed:15009089, PubMed:25575561).  Regulates tubulin acetylation in ALM and PLM neurons (PubMed:25575561).
What are the official names of this protein?
Thioredoxin domain-containing protein 9.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ABAN1_LIMMU
Sequence: LVALDTEFANR
What is the function of this protein?
Has antibacterial activity against L. monocytogenes.
What are the official names of this protein?
Antibacterial peptide AN1, Bacteriocin AN1.
What are the subcellular locations of this protein?
Secreted.
Protein: LOLA_VIBVY
Sequence: MKKWLVVFFLSASALANPQQELNQRLGMNDGFSANFNQTVTSPEGEVVMEGEGSVDIARPSLFRWSTSLPDENLLVSDGKTLWYYSPFIEQVSIYWQEQAVQQTPFVLLTRNQSSDWENYQITQDGNVFTLVPKAADSTQGQFQIDIDAKGIVHGFNVIEQDGQKGIFKFTDMKLGKPAAARFTFNIPEGVEVDDQRN
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.