PharMolix/UniProtQA huggingface dataset:
Protein: PACC_PENEN
Sequence: ERHVGRKSTNNLNLTCQWGTCNTTTVKRDHITSHIRVHVPLKPHKCD
What is the function of this protein?
Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH.  At alkaline ambient pH, activates transcription of alkaline-expressed genes (including pacC itself) and represses transcription of acid-expressed genes (By similarity).
What are the official names of this protein?
pH-response transcription factor pacC/RIM101.
What is the protein family that this protein belongs to?
Belongs to the pacC/RIM101 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEA_CLOK1
Sequence: MEVTDFDFYLPEELIAQKPLEQRDEGRLMVLDKKTGKVCHKIFKDIVYYLNPGDCVVLNDTRVLPARLIGVREDTMGKIEFLLLKRRDNFTWETLVKPGRRAKVGNRFNFGSGQLKAEVVSINEDGNRIVRFEYNGVFEEILDKLGQIPLPPYIKEKLENKELYQTVYSKEEGSAAAPTAGLHFTEELLRELREKGVNLAFLTLHVGLGTFRPVKVENIEDHAMHSEFYSMSKETADMINAAKESGHSVISVGTTSCRTLETIGDENGRVKEQSGWTDIFIYPGYKYKVVDKLITNFHLPKSTLIMLVSAFYGRENTLHAYNVAVKEKYRFFSFGDAMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPI10_ASPFU
Sequence: MSSSRRRKSFTSSSSSSSPSFHSPPPTSRLRPRSPPSSNTKTSPTSTTPLATNILLSLIAFRLVNAFTVRTFFQPDEFFQSLEPAWQIAFGENQGAWITWEWRHQLRSSIHPLLFAAVYSAADVVAQLLRLSLASRADLLVAAPKTAQAVIAGLGDFYTWKLARYVYGARSYEAWATLALTVVSPWQWFCSTRTLSNCLETTITIVALYLWPWSWSFETPVRKKATRAASRERAQRGPEGSDSLQRLRQCLSLAAVACILRPTNILIWMGLASVAWFRTSWDRRAILVREVLLCGCAVLGLSCVVDRLFYGSWTFPPLRFLYFNIAQSLAVFYGRNDWHYYVSQGFPLLLTTALPFALVGLYRALAQVRTFGLGHLQSLVQAQLALICVIMPFVLSLVSHKEVRFIYPLLPSLHILSAPPLVDYFLPAVIRSSRSYTPRRLTLIFLLLVNIVIALYTTIYHASGPSNILSYLRQQHELHAPAAQTPSNLRPSVKDPSPHGITAGFLMPCHSTPWRSHLIYPTIHAWALTCEPPVDQTAAQKATYIDEADQFYANPARFLREHMAGGLRHISRKPSYLSAQPRPQHPSTTSTNDASHEWPDYLIFFAQLEPTLQSLLRASSYAECYRTFNTAWHDDWRRKGDIVAWCLDPAEQQAWRSATRQRDLENRERQFDRIIESFRKEASGKRDGKLSPFRRWFSSSSSVAPSSSLSLSWPTSWRWPWGQRKRTAWLGVQIPQWTRTRPSWTAWGGDWFGGWRQKKKTKKLLERDLWS
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 3, GPI mannosyltransferase III, GPI-MT-III, Glycosylphosphatidylinositol-anchor biosynthesis protein 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MSRQ_ECO27
Sequence: MRLTAKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGLTALKFLLAALLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWVILLALAFTSTQSMQRKLGKHWQQLHNFVYLVAILAPIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLLSLFNRLRKQAHNKLSL
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FRDC_ECOL5
Sequence: MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL11_LACP7
Sequence: MAKKVTGYIKLQIPAAKATPAPPVGPALGQHGVNIVQFTKEFNARTANQEGMIIPVVITVYADRSFSFITKTPPAAVLLKKACNLKSGSAAPNKTKVATIKKSEVQKIAELKMPDLNAANVETAISMISGTARSMGITVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RBSA_BURMA
Sequence: MDTILALTGITKRFPGVVALRGIDLRVARGEIHALLGENGAGKSTLMKILCGIHPPDEGVIALDGEPRRFANHHDAIAAGVGIVFQEFSLIPELNAVDNLFLGREWRGRLGLRERARMRRAAADIFARLDVAIDLSAPVRELSVAQQQFVEIGKALSLDARLLILDEPTATLTPAEAAHLFGVMRELKRRGVAMIFISHHLDEIFEVCDRITVLRDGQYVGTTEVARTDVGALVEMMVGRRIEQSFPPKPRLARDAAPVLEVDALQVRENGPVNRFALREGEILGFAGLVGSGRTSSALALIGAKPARVRRMRVRGRPVRLADPAAALAAGIGLLPESRKTQGLIPAFSIRHNIAINNLGKHRRLRWFVDAAAETRTTLELMQRLGVKAPTPHTRVDTLSGGNQQKVVIARWLNHHTRILIFDEPTRGIDIGAKAEIYQLMRELSARGYSIVLISSELPEIVGLCDRVAVFRQGRIEAMLEGEAIEPNTVMTYATSDVRGANHEHA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSA7_SCHPO
Sequence: MSSIGTGYDLGLFFSPDGRLFQAEYAYKAVENASTCIGIKCEDGVILALEKVVTSKLLKPRVNNRIGSVDRHIGIATTGFIPDGQHIVKRARDEATSWRDNYGSPIPGTVIADRLGNYVQLFTCYSSVRPFGVMSFVATYDSEGPHLYMVEPNGVYWGYNGAAAGKGRQVARNELEKLNFSSLKMKDAVKEAARILYATHDEENNKEHEIEMTWVGVETNGIHTPVPDELLQEAEAYARRIADGEEEDIAMQE
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (By similarity).
What are the official names of this protein?
Probable proteasome subunit alpha type-7.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: VNS1_BTV10
Sequence: MERFLRKYNISGDYANATRTFLAISPQWTCSHLKRNCLFNGMCVKQHFERAMIAATDAEEPAKAYKLVELAKEAMYDRETVWLQCFKSFSQPYEEDVEGKMKRCGAQLLEDYRKSGMMDEAVKQSALVNSERIRLDDSLSAMPYIYVPINDGQIVNPTFISRYRQIAYYFYNPDAADDWIDPNLFGIRGQHNQIKREVERQINTCPYTGYRGRVFQVMFLPIQLINFLRMDDFAKHFNRYASMAIQQYLRVGYAEEIRYVQQLFGRVPTGEFPLHQMMLMRRDLPTRDRSIVEARVRRSGDESWQSWLLPMIIIREGLDHQDRWEWFIDYMDRKHTCQLCYLKHSKQIPTCSVIDVRASELTGCSPFKMVKIEEHVGNDSVFKTKLVRDEQIGRIGDHYYTTNCYTGAEALITTAIHIHHWIRGSGIWNDEGWQEGIFMLGRVLLRWELTKAQRSALLRLFCFVCYGYAPRADGTIPDWNNLGNFLDIILKGPELSEDEDERAYATMFEMVRCIITLCYAEKVHFAGFAAPACEGGEVINLAAAMSQMWMEY
What are the official names of this protein?
Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the orbivirus non-structural protein NS1 family.
Protein: SARR_STAAB
Sequence: MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRSESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANIQKLISELEEYIKN
What is the function of this protein?
Negative regulator of sarA transcription at late exponential and stationary growth phases.  It contributes to the modulation of target genes downstream of the sarA regulatory cascade.  Also, positively regulates expression of primary transcripts RNAII and RNAIII generated by agr (virulence accessory gene regulator) locus (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator SarR, Staphylococcal accessory regulator R.
What is the protein family that this protein belongs to?
Belongs to the SarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP6B_SULTO
Sequence: MSSEKFTSISPAEFFKRNPELAGFSNPARALYQTVRELVENALDATDVHNILPSIKIIIELVDPQKQIYKVNVEDNGIGIPPHIVPNAFGKVLYSSKYVLRQTRGMYGLGVKAAVLYSQMYQERPVEVVTSPINSKRIYFFKLKIDVVKNEPIILQKTSVVNEKNWHGTSVTLYLYADWQRAKQKIYEYVKKTYIISPYAEFFFKDPDNNVIYYKRLTDKIPEPPKEVKPHPYGVDIELIKFMIVKKDKPVPVRDFLINEFQSIGDVTADKILEMAKLPKDKKTTELTDEEISRLVEVMKKFDDFRPPSAEALSVIGEDLIKLGLKSIFNPEFAEAITRKPKAYQGHPFIVEAGIAYGGAIQPSPEPIVLRYANKIPLIYDEKSDVIWKVVTEEMDWKRYGIEEEQPPLVVMVHLCSTKVPYRSAGKESIADVEEIEKEIKLALMDVARKLKKYITEKRKEEEAKKRLITYLKYIPEVSRGLALFLVGGDKQKIGDAYSDLREKLLKIALNKLEVNDKKLEEEIRNYKVEEL
What is the function of this protein?
Relaxes both positive and negative superturns and exhibits a strong decatenase activity.
What are the official names of this protein?
Type 2 DNA topoisomerase 6 subunit B, Type II DNA topoisomerase VI subunit B, TopoVI-B.
What is the protein family that this protein belongs to?
Belongs to the TOP6B family.
Protein: YBEY_MYCCT
Sequence: MLKINYFNDTDVNMNSWKKFANKILKIAYNYFNFNYDIELSITFVDDLKAQQINQQYRNHSYIADVTSFPVEMTENEIKAIGFRELGDMFINLSEAKRKAIKYNHDLNSEMGFLFVHGFLHLLGYDHENLDDEKIMFDLQDQILKLNNLVYIIKFNEEDYLESN
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1174_PELPB
Sequence: MAMPNLGDMMKQIQQAGEKMQDVQKQLEKIVAHGEAGGGMVKVSVSGKQKLLSLTIDPDIMDDAEMVQDLVLAAVNNALDESARLAQEEISKVTGGMMNPADILKNLNLGQ
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Ppha_1174.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ASTB_LEGPA
Sequence: MNAYELNMDGLVGQTHHYAGLSSGNIASTNNALSISNPQAAARQGLEKMRQLYNMGLKQGLLPPHQRPNLNLLYQLGFKGSPSEQINKAYKTAPELLSACYSASSMWTANAATVSASVDTEDNKVHFTAANLISNLHRHQEADFSKKLLEFIFSNSDYFNHHPLLPKSMGTSDEGAANHNRLCQSHAHSGINLFVYGKKVLGNHQFEQSPIKYPARQTKEASEAIARNHLLNPERVIFACQNPLAIDQGVFHNDVISVANEHVFLVHEEAFYNQAYVLDQLKEKADFPLVIIQISKEQISVSEAVDTYLFNSQLITLPDQKNMILIAPAECQANLKVKTCIDGLVADSQNPINSVYYLDLKQSMRNGGGPACLRLRVPLNDYELKAMHQGILIDNDLLDILDKWVLKYYRTELKISDLADPQLLYECLDALDELTQILKLGSIYPFQS
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: RL20_MYCFE
Sequence: MRVKGGTVTRARRKKWLKLAKGYFGHKSIGYKVAKQAVVKSWTYAFRDRKQIKREFRKLWIARINAATRAEGLSYSKFINGLKRANVTINRKMLSELAISEPKTFAMLIKIARDAK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit (By similarity).
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: YKUI_BACSU
Sequence: MLDPLDILTNIDDVLPYYQAIFSAEEQKVVGYEVLGRILADSEIQSLGPFFLDAGIPEEYKLEVDNRIIRQALDRFLEADSDLLIFMNQDANLLMLDHGESFLELLKEYEAKGIELHRFVLEITEHNFEGDIEQLYHMLAYYRTYGIKIAVDNIGKESSNLDRIALLSPDLLKIDLQALKVSQPSPSYEHVLYSISLLARKIGAALLYEDIEANFQLQYAWRNGGRYFQGYYLVSPSETFLERDVLKQRLKTEFHQFITHEKKKLETVYEHSEQFYKRVHQAVTSLRKNNLSSDDDFIKKLAEELTDCSFRIYMCDEEGDQLTGNVFKQDGEWIYQPEYAEKNWSWRPYFLENIMRMRNLRKGFFSDLYSDLETGEMIRTFSYPMDDQMYLFIDLPYSYLYEQDGLI
What are the official names of this protein?
Uncharacterized EAL-domain containing protein YkuI.
Protein: BRI3_HUMAN
Sequence: MDHKPLLQERPPAYNLEAGQGDYACGPHGYGAIPAAPPPPPYPYLVTGIPTHHPRVYNIHSRTVTRYPANSIVVVGGCPVCRVGVLEDCFTFLGIFLAIILFPFGFICCFALRKRRCPNCGATFA
What is the function of this protein?
Participates in tumor necrosis factor-alpha (TNF)-induced cell death (PubMed:14592447).  May be a target of Wnt/beta-catenin signaling in the liver (PubMed:20538055).
What are the official names of this protein?
Brain protein I3, pRGR2.
What is the protein family that this protein belongs to?
Belongs to the BRI3 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm, perinuclear region. Note=Co-localizes with MGAT1 and IFITM3 at the perinuclear region. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Nucleus. Note=Diffuse localization in the cytoplasm and nucleus.
Protein: SODM1_STAAB
Sequence: MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVEGTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKIKEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGLDVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe] 1.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: RIMO_CHLL3
Sequence: MPHPEHNTSVFLLSLGCSKNTVDSERLQAQAEASGITFTQQAEEAEVILINTCGFIEDAKEESIMEILAAVDMKNAGTVRQVYVMGCLTELYRNELQEELPEVDRFFGTRELPAVLDALGARYHQELYDHRSLLTPPHSSYLKIAEGCSRACSFCSIPKIRGRYLSQPMEQLLREARLLQENGVKELNLIAQDITVYGVDLYGKQMLNDLLMRLSDMEFRWIRLLYAYPVGFPLEVIDTIGNRSNICNYLDLPLQHCSDPILRSMNRGITKEQSLRLIEEIRNRNPDIRLRTTMIAGYPGETRKEFEEMLEFAGSVRFDRLGCFPYRHEEHSPAYSLIDTVPEEEKQERVSELMELQEEIARKKNEAFVGSLMTVLVDRPEEGEEGLILIGRTEFDAPEVDNECLLESGSPEPSPGTFVQARITGSTAYELHGTVESLME
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFM_BOVIN
Sequence: MSYTLDSLGNPSAYRRVTETRSSFSRISGSPSSGFRSQSWSRGSPSTVSSSYKRSALAPRLTYSSAMLSSAESSLDFSQSSSLLDGGSGPGGDYKLSRSNEKEQIQGLNDRFAGYIEKVHYLEQQNKEIEAEIQALRQKQASHAQLGDAYDQEIRELRATLEMVNHEKAQVQLDSDHLEEDIHRLKERFEEEARLRDDTEAAIRALRKDIEESSLVKVELDKKVQSLQDEVAFLRSNHEEEVADLLAQIQASHITVERKDYLKTDISTALKEIRSQLESHSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRQPSIAISSKIQKTKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSVKEEVKEEEAEEKEEKEEAEEEVVAAKKSPVKATAPELKEEEGEKEEEEGQEEEEEEEEAAKSDQAEEGGSEKEGSSEKEEGEQEEEGETEAEGEGEEAAAEAKEEKKMEEKAEEVAPKEELAAEAKVEKPEKAKSPVAKSPTTKSPTAKSPEAKSPEAKSPTAKSPTAKSPVAKSPTAKSPEAKSPEAKSPTAKSPTAKSPAAKSPAPKSPVEEVKPKAEAGAEKGEQKEKVEEEKKEAKESPKEEKAEKKEEKPKDVPEKKKAESPVKAESPVKEEVPAKPVKVSPEKEAKEEEKPQEKEKEKEKVEEVGGKEEGGLKESRKEDIAINGEVEGKEEEQETKEKGSGGEEEKGVVTNGLDVSPGDEKKGGDKSEEKVVVTKMVEKITSEGGDGATKYITKSVTVTQKVEEHEETFEEKLVSTKKVEKVTSHAIVKEVTQSD
What is the function of this protein?
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber.  May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
What are the official names of this protein?
Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, axon.
Protein: POG1_YEAST
Sequence: MKQEPHRQSEEKEKPKGPMAVEREQHTSLSSGTTVTASTGDESTNSRPVESSQTEKSLSLRIRILKQLGFDDIQELNACDTGLVEQFLNVRLINDTKELEKIRESNLAKLNQIIDKCMESDKISDSTLNKILDMSMNRDTNNDNNNHLTIPSPITTKKRKINASELASPRGHRRYRSDIPTVSEVETGVGYPQIHQQPGAYTLPMPANQWMSNPYMQPPQPQVQQIMPQYLYPPGMGPQAQLPTMSSNSESQTPVMSSQFLSLNQHGLYQQNIGAHPVMSMGPQANIYGQQHQLQPGQERDQSRKSFSHRRSQSANISMANFRSPMRNPQPASSQRPVNFLIHTPKHPPPT
What is the function of this protein?
Transcriptional activator which promotes cell cycle recovery with CLN2, after pheromone induced G1 arrest, probably inhibiting the ability of STE20 to activate the pheromone response pathway.  Binds the promoters of genes that function in cell cycle regulation, cytoskeletal organization, and spindle assembly.  May also be involved in stress-resistance.
What are the official names of this protein?
Transcriptional activator POG1, Promoter of growth protein 1.
What is the protein family that this protein belongs to?
Belongs to the POG1 family.
Protein: ATPB_DESAP
Sequence: MNVGEVVQIIGVVVDVRFPPGQVPEIYNALTIETDKVDAFGRKFNLTLEVAQHLGNNVVRTVAMSTTDGLVRGAKVVDTGAPIKVPVGRPVLGRLIDVLGMPIDGLGDIKAETYYPIHRPAPALVDQSTKVEQLETGLKVIDLLVPFMKGGKIGMFGGAGVGKTVIVMELINNIAKQHGGISVFAGVGERTREGNELLLEMTEAGVLDKTMMVFGQMNEPPGCRLRVGLTGLCLAEYFRDEEGADVLIFIDNIFRFAQAGTEVSALLGRMPSAVGYQPTLATEMGQLQERITSTTKGSITSVQAVYVPADDLTDPAPANTFAHLDGTVVLSRQIAELGIYPAVDPLDSVSRILDPNVVGQEHYQVARGVQKVLQRYKELQDIIAILGMEELSEEDKLIVARARKLQRYLSQPFHVAEAFTGTPGRYVSLKDNIRGFQEILDGKHDGLPEDAFYMVGTIEEAVEKGKKILEAS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HXA5_SHEEP
Sequence: QTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDN
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Also binds to its own promoter.  Binds specifically to the motif 5'-CYYNATTA[TG]Y-3' (By similarity).
What are the official names of this protein?
Homeobox protein Hox-A5.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: 3MGH_LEGPA
Sequence: MRKLLRPFYERDTVLVAKELLGKYLVHHDGLEEKIGRIVEVEAYLGQHDLACHSSKGLTKRTKVMFGPAGYAYVYLIYGMYYCMNVVTEKEGIGSAVLIRALEPIKNIQDRTQGPGLLSKAMRIDSKLNHRDLLSNDFYIAEPNSPTDFTIIEKPRIGVHYAKEWANELLRFYIKDNPYISKT
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: NDHJ_CROS5
Sequence: MVDENTQDNAPEQEEEAAIVQAGPVSSWLTENGFDHDLLEPDHLGVELIKVSPDFLVPLCTALYAYGFNYLQCQGAYDLGPGKELVSFYHLIKVSDNCEQAEEVRIKVFLPRDNPHIPSVYWIWKAADWQERESYDMYGIIYDGHPDLKRILMPEDWVGWPLRKDYVSPDFYELQDAY
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit J, NAD(P)H dehydrogenase subunit J, NADH-plastoquinone oxidoreductase subunit J, NDH-1 subunit J, NDH-J.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DEOB_SALPB
Sequence: MKRAFIMVLDSFGIGATEDADRFGDVGSDTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLVKAHEGSTGKIAAGMDGNADVIGAYAWAHELSSGKDTPSGHWEIAGVPVLFDWGYFSDHENSFPQELLDKLVKRANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTEGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKQGHVVSVGKIADIYANCGITKKVKATGLDALFDATLKEMKEAGDKTIVFTNFVDFDSSWGHRRDIAGYAAGLELFDRRLPELMELVGEDDILILTADHGCDPSWTGTDHTREHIPVLIYGPKVKPGSLGHRETFADIGQTLATYFGTSPMDYGKNML
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_SHIB3
Sequence: MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKSMQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDGLTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.