PharMolix/UniProtQA huggingface dataset:
Protein: FMT_NATTJ
Sequence: MRTIFMGTPDFSVPFIEAIARSTHNLNLVVTQPDRRKGRGKELQPPPAKRKAEELGIDVFQPESIHNNYAYQILSDIEPHLIVTAAYGQILPRKILDLPRIKAINVHASLLPEYRGAAPIHRAVMDGKEQTGVTIMEMCDKMDAGDILNYESVDIGKTDTTGDVYKQIITVGPQLLIETMDLLEKNQVTPLKQDENQVSYAPKLKKEDEYLDFSKYTNTEVFNRVRGLNPWPGAFTKFEGKRLKIWETKVHNSSSFNSNSKPGEIIEINQQGPVVKCCQGSVILTKIQPSGKKAMTGEQFIRGYDIKSGIQLE
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: D106A_PONPY
Sequence: MRTFLFLFAVLFFLTPAKNEFFDEKCGKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID
What is the function of this protein?
Has antibacterial activity.  Acts as a ligand for C-C chemokine receptor CCR2.
What are the official names of this protein?
Beta-defensin 106A, Defensin, beta 106, Defensin, beta 106A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=Associates with tumor cell membrane-derived microvesicles.
Protein: ENO_STRAW
Sequence: MPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDPNRYQGKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAHAASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALRWGAEVYHTLKKVLKTKGLSTGLGDEGGFAPNLESNRAALDLIIEAIKQAGYIPGEQIALALDVAASEFYKDGKYEFEGKSRSAAEMTEYYEELVSAYPLVSIEDPLYEDDWAGWKVITDKLGDKVQIVGDDLFVTNPERLARGIEEGSANALLVKVNQIGSLTETLDAVELAQRNGFKCMMSHRSGETEDVTIADLAVAVNCGQIKTGAPARSDRVAKYNQLLRIEEILDDAAEYAGRSAFPRFRSAN
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: EIF3J_BOVIN
Sequence: MAAAAAGDSDSWDADTFSVEDPVRKVGGGGTAGGDRWEGEDEDEDVKDNWDDDDDEKKEEAEVKPEVKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNTVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYANFLEALVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDGGYAQDYEDFM
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.  The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).  The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.  The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.  This subunit binds directly within the mRNA entry channel of the 40S ribosome to the aminoacyl (A) site.  It may regulate the interaction between the 43S PIC and mRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit J, eIF3j, Eukaryotic translation initiation factor 3 subunit 1, eIF-3-alpha, eIF3 p35.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit J family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLC3_PONAB
Sequence: MSVQVAAPGSAGLGPERLSPEELVRQTRQVVQGLEALRAEHHGLVGHLAEALAGQGPVTGLEMLEEKQQVVSHSLEAIELGLGEAQVLLALSAHVGALEAEKQRLRSQARRLAQENVWLREELEETQRRLRASEEAVAQLEEEKRHLEFLGQLRQYDPPAESQQSESPPRRDSLASLFPSEEEERKGPEAAGAAAAQQGGYEIPARLRTLHNLVIQYAGQGRYEVAVPLCRQALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFEDVERHYARALSIYEALGGPHDPNVAKTKNNLASAYLKQNKYQQAEELYKEILHKEDLPAPLGAPNTGTAGDAEQALRRSSSLSKIRESIRRGSEKLVSRLRGEGAAGAAGMKRAMSLNTLNVDAPRALGTQFPSWHLDKAPRTLSASTHDLSPH
What is the function of this protein?
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport.  Plays a role during spermiogenesis in the development of the sperm tail midpiece and in the normal function of spermatozoa (By similarity).  May play a role in the formation of the mitochondrial sheath formation in the developing spermatid midpiece (By similarity).
What are the official names of this protein?
Kinesin light chain 3.
What is the protein family that this protein belongs to?
Belongs to the kinesin light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Mitochondrion. Note=In elongating spermatid tail midpiece, localized in outer dense fibers (ODFs) and associates with mitochondria. Also localizes to the manchette in elongating spermatids.
Protein: RS7_RICRS
Sequence: MSRRHAAEKRVILPDMKYNSILLSRFINNIMKEGKKALAEKIVYSAFNKIEKKHRVDPYQAFNNAMHNVKPHLEVTSVRVGGANYQVPTHVDERRGYALASRWIINAASKRSEKMMIDKLAEELFEASNNRGVAIKKKEDTHKMAEANKAFSHFSPKKMK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: YJV7_SCHPO
Sequence: MTIDWRQIAAKYCAHRDGSIPEPFKIKTLPKDTVLNVTKIPSECGLLTPKEIELTEKYDATALAEMIKDRKVTSVELVTAFCKRAAIAQQLVNCVNELFYEEALARAAELDEYYAKTGSLVGPLHGVPVSVKEHISIKNHTATASFLAKANIIAEKDSDLVATVRKAGAVFYCRTPQPQAIMHLETSSNLTGVTVNPFNRKLTPGGSSGGEGALLGIKASVLGIGSDIGGSIRSPAANNGLFGLRPSTLRLSRKGCQGAVSGQETILGVVGPLGRSVRDMNLFMKACIDSQPWLDDASLLPMPWRSVAPPKTLKVGIMRSDNVVNPQPPVARAMQMAIDQLSKNPDFDLVDVEPLDHKYSWDLISEMYWLDGGKVYYDLFNKVGEPILPLTEWIMHQPNVKPHDITAVWKLTAARDEYRNRYLKHLQAYGVDVLLTPVGPSPAPKLGEAKYWTYTSVWNLLDLPAVVFPVTTVDPKLDVKDESYIPMNEQDAANYETYSPEDYLDAPVSLQLVGKRWQDEELLAALDKIVSML
What are the official names of this protein?
Putative amidase C550.07.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPE_BACC3
Sequence: MKTFPVSIVTPDGPVYEKEVEMVSVKAESGEMGILPGHIPTVAPLKISAVRLKNGGHTDYVAVSGGFIEVRPDKVTVLSSSAEEANHIDIHRANEAKRRAEQRLQDKQAHVDFKRAEMALQRAVNRLNVSDMK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: G1091_SHESM
Sequence: MHNIHRRHFLKAAGAVTAGLVTANIALNANASSVAPKPRVGKSVIGLIAPKMELVRVGFIGVGERGFSHVEQFCHLEGVELKAICDTHQAVIDRAVEHIVNQNRPKPAVYTGNDLSYRELLNRDDIDIVIISTPWEWHAPMAIDTMESGKHAFVEVPLALTVEECWQLVDTAERTQKNCMMMENVNYGREELMVLNMVRQGVFGELLHGEAAYIHELRWQMKEIDHKTGSWRTYWHTKRNGNLYPTHGLGPISQYMNINRGDRFDYLTSMSSPALGRTLYAKREFPADHERNQLKYINGDMSTSLIKTVKGRTIMVQHDTTTPRPYSRHNLIQGTNGVFAGFPNRIAVEHGGFGKSYHEWDMDMQKWYDKYDHPLWQRIGKEAEINGGHGGMDFVMLWRMVYCLRNGEALDQDVYDGAAWSVVNILSEQSLNNRSNSVNFPDFTRGAWKHATPLGIVGA
What is the function of this protein?
Glycosidase.
What are the official names of this protein?
Glycosyl hydrolase family 109 protein 1.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
Protein: S17A9_HUMAN
Sequence: MQPPPDEARRDMAGDTQWSRPECQAWTGTLLLGTCLLYCARSSMPICTVSMSQDFGWNKKEAGIVLSSFFWGYCLTQVVGGHLGDRIGGEKVILLSASAWGSITAVTPLLAHLSSAHLAFMTFSRILMGLLQGVYFPALTSLLSQKVRESERAFTYSIVGAGSQFGTLLTGAVGSLLLEWYGWQSIFYFSGGLTLLWVWYVYRYLLSEKDLILALGVLAQSRPVSRHNRVPWRRLFRKPAVWAAVVSQLSAACSFFILLSWLPTFFEETFPDAKGWIFNVVPWLVAIPASLFSGFLSDHLINQGYRAITVRKLMQGMGLGLSSVFALCLGHTSSFCESVVFASASIGLQTFNHSGISVNIQDLAPSCAGFLFGVANTAGALAGVVGVCLGGYLMETTGSWTCLFNLVAIISNLGLCTFLVFGQAQRVDLSSTHEDL
What is the function of this protein?
Involved in vesicular storage and exocytosis of ATP.  May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles.
What are the official names of this protein?
Solute carrier family 17 member 9.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYREL_METMP
Sequence: MKKELILKALKLRDMGFPSGDIAEELNISVKTALYLTLNGEELLKAEESPKEDSEKLDIFLEWDNVRASSRRLRNISKIICDMLSDVEFDGVVGISSGGVPLATLISDELDKNFSIYVPKKHIHTEKEKTTGFIGQNMSSIVGKDVIIVDDVMTSGNSVKETIKYLKGIANPKKVFVVMDKSGIDEIEGVSIEHLFRTGVVDIKK
What are the official names of this protein?
PyrE-like protein.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: PRS4_ENCCU
Sequence: MSRDKSERDNLQDTTTINLRRRRRVKEGKAASKPPQVYPLMKCKLRYLKLKKLAHLLSLEDNILSLCEPDKSSEGSNSQKHVVEQLRGSPLSVGTLEEFVDDHHGIITTGVGLEYYVNIMSFVDKDLLEPGCTVLLNYKDNSVVGVLEGEMDPMVNVMKLEKAPSETYADIGGLEEQIQEIKESVELPLTNPELYQEMGIKPPKGVILYGLPGTGKTLLAKAVANQTSATFLRVVGTELIQEYLGEGPKLVRELFRVADMHAPSIIFIDEIDAIGGKRYNTSSGGRREVQRTMLELLNQLDGFDTRNDIKVIMATNKIEALDPALIRPGRIDRKIEFGMPDAATKKKIFDIHTSRMTLDESVNIELLITSKEDLSGADIKAICTEAGMIALRERRKTVTMKDFISAREKVFFSKQKMVSAGLYS
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus.  It is essential for the regulated turnover of proteins and for the removal of misfolded proteins.  The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH (By similarity).
What are the official names of this protein?
26S proteasome regulatory subunit 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COBQ_CLOD6
Sequence: MGKKIMLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFITKEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDYKLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGDIDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGVVPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVDYGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKKLKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGYEIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAILNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: CYP1_USTMD
Sequence: NTHTLPGLGRLIDVSRPDWIEHVQKTNFSNYVKGEQFHDQMRDVLGDGIFTSDGERWKMQRKVASRIFTVSSFKAIITQTIREDCALVEKLIETYAKEGTVFNLQELYFKFTLSSFVKIAFSQDIMSLSEPDRPDTFGDAFNYAQKVLDMRFVQPWWKIAERFNETGRKMRAARKIVEEFTNNIVEARREESDAMGEKSKPESGRKDLLDLFMGYRSSDGQRLSNQQLKDTILNLMIAGRDTTAEALSWMSWHMLTKPEVYSRIRREIDTSLDEDGEQAGLEIDYDVFEQHTAKLSTFQETLRLHPSIPKNIRRALKDDVLPNGGPRVRKGDLMLYSDWAMARNPDIWGPDACEFKPSRWIDEETGSTVKYSQFQAHFFNGGPRLCLGQKLASYEVVQLIHHIFAKFDLELVDLGPKKSAGFDKVPDYLNSLTHP
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the glycolipid biosurfactant ustilagic acid (UA) (PubMed:15932999, PubMed:17850255, PubMed:22985214).  UA is a secreted cellobiose glycolipid that is toxic for many microorganisms and confers biocontrol activity to U. maydis (PubMed:15932999, PubMed:17850255, PubMed:22985214).  UA consists of 15,16-dihydroxypalmitic or 2,15,16-trihydroxypalmitic acid, which is O-glycosidically linked to cellobiose at its terminal hydroxyl group (PubMed:17850255).  In addition, the cellobiose moiety is acetylated and acylated with a short-chain hydroxy fatty acid (PubMed:17850255).  UA biosynthesis starts with omega-hydroxylation of palmitic acid catalyzed by the cytochrome P450 monooxygenase cyp1 (PubMed:17850255).  Terminal hydroxylation of palmitic acid precedes subterminal hydroxylation catalyzed by the cytochrome P450 monooxygenase cyp2 (PubMed:17850255).  Sequential glucosylation of the hydroxy fatty acid is probably catalyzed by the glycosyltransferase ugt1 (Probable).  The cellobiose lipid is further decorated by acetylation of the proximal glucose residue and by acylation with a short-chain beta-hydroxy fatty acid at the distal glucose residue (Probable).  The acyltransferase uat1 may be a good candidate for catalyzing either acetylation or acylation of the cellobiose lipid (Probable).  The fatty acid synthase fas2 may be involved in synthesis of the carbon backbone of the short-chain beta-hydroxy fatty acid esterified to the cellobiose disaccharide (Probable).  The secreted UA consists of a mixture of both alpha-hydroxylated and non-hydroxylated glycolipids; therefore, alpha-hydroxylation of the long-chain fatty, catalyzed by the fatty acid hydroxylase ahd1, occurs late in UA biosynthesis and may be the last step before secretion (PubMed:17850255).
What are the official names of this protein?
Cytochrome P450 monooxygenase cyp1, Ustilagic acid biosynthesis cluster protein cyp1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: PP1R8_ARATH
Sequence: MYGRSGLDRFKKSQTSEPFSVSANPPPVVQQHLSPEALSGQKTQIGAGQSNWHPPDWAIEPRAGVYSLEVVKDGQILDRIHLDRRRHIFGRQHQTCDFVLDHQSVSRQHAAVVPHKNGSIFVIDLGSAHGTFVANERLTKDTPVELEVGQSLRFAASTRIYLLRKNSEALFSRPPPPAEIKLPPPPDASDEEAVVAYNTLLNRYGLSNGESGGMLGKRKEKTGSEAGVAKRMKKVRVSFRDQLGGELAEIVGMSDGADVETEPGPINVKEGSLVGKYESLVRVTLIPKGKVKEEKAFTGGTRGGVTDRLQEAMNMLKRGPKTGIYDDLYGGDSLAKAVGTSWASVSQPAAETECGGVGEEDDNDDLFGD
What is the function of this protein?
Inhibitor of protein-phosphatase 1 (PP1).  Binds to and inhibits PP1 activity.
What are the official names of this protein?
Protein phosphatase 1 regulatory inhibitor subunit PPP1R8 homolog.
Protein: DUT_BIFLO
Sequence: MAFDETYNEPESTEVLVKSLDPEHPAQLHYAHAGDAGADLITTVDVTLKPFERALVPTGVAIALPAGYVALVHPRSGLAAKQGVTVLNAPGTVDAGYRGEIKVPLINLDPKHTAVFHPGDRIAQLVIQRYVEARFIPAETLPGSDRAERGFGSTGVAS
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PFD1_DANRE
Sequence: MAAPVDLELKKAFAELQAKMVDTQQKVKLADLQIEQLSRVKKHANLTHGEITSLPESTRMFEGAGRMFILQSKGEISNQLLEKQKTADDKIKELEQKKTYLERSVKDAEDNIREMLMSRRAQ
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity).
What are the official names of this protein?
Prefoldin subunit 1.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: ISPD_RUTMC
Sequence: MPSHYYLIIPASGVGVRMHPEKDGLNEQPKQYLKLDNGLTILDQTLKTLLSINQIKSCVIAIKNKDHLFAKSAFNNHPKLLTIVTGGKERMYSVLNALKALIDFAKDDDWVLVHDSVRPCVKASEIINLMKQLKHHATGGLLATKVVDTIKQADNNIINTTIDRSNLWQAQTPQMYRFSVLLKALNTAIKDGINITDETSAIEHLGLESILVKSSKSNIKVTNPEDLILANFYLNQHQK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TRUA_HYDS0
Sequence: MKNYKFTISFVGTNYSGWQYQPNVPTIQNEVEEKLYYIVNKKKPIKQKIRAIGCSRTDKGVHAIEFVFNVKMEFDKDLNFLRKALNSALPKDIKIHNIEEVPLEFNSRFDALKKTYIYKLFFDEKNSPFFQDRAMLVYKPTDLGKMMEISHLFLGYKDFRGFTKELEDENGYCSVENITFKVDYPLVEISITANRFLRYMVRRMVGTMLSYAQGLISIDDVNDFLKAKRVSNHTAKAHGLYLKKVYY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GOSR2_CAEEL
Sequence: MEALYQSTNFLLQKVQHDLGRLEGTQNEQDAQVVVQCIYGDVITLKENCQTLDNYVSREPPARRQAARMRVDQLRADVHRVDMAVSAVHTRMTQRWRAATERDELLRTRYRPNDTALSIGDHELLLNDRLQSSHTHLDDLISQGSAVLENLKSQHLNLRGVGRKMHEIGQALGLSNSTLQVIDRRVREDWILFVIGCIVCCIFMYAFYRFWRG
What is the function of this protein?
Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
What are the official names of this protein?
Golgi SNAP receptor complex member 2 homolog memb-1.
What is the protein family that this protein belongs to?
Belongs to the GOSR2 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Single-pass type IV membrane protein. Golgi apparatus membrane. Endoplasmic reticulum membrane. Note=Concentrated most in the intermediate compartment/cis-Golgi network and the cis-Golgi cisternae 1 and 2. Greatly reduced in concentration at the trans end of the Golgi apparatus.
Protein: HSLO_STAHJ
Sequence: MTHDYIVKSLAFDGEIRAYAALTTESVQEAQTRHYTWPTASAAMGRTMTATLLMGSMLKGEQKLTVTVDGKGPIGRIIADADAEGNVRAYVDKPQTHFPLNEQGKLDVRRAVGTDGSIQVVKDVGMKDYFSGASPIVSGELGEDFTYYFATSEQTPSSVGLGVLVNPDNSIKAAGGFIIQVMPGAKDETVTKLENAINNMQPVSKLIEQGLTPEGILNEILGEDNVQILETMQAQFECNCSHEKFLNAIKGLGEAEIQDMIKEDHGAEAICHFCGNKYNYSEAELEDLLASMNA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END3_THEMA
Sequence: MIEELAREIVKRFPRNHKETDPFRVLISTVLSQRTRDENTEKASKKLFEVYRTPQELAKAKPEDLYDLIKESGMYRQKAERIVEISRILVEKYGGRVPDSLEELLKLPGVGRKTANIVLWVGFKKPALAVDTHVHRISNRLGWVKTRTPEETEEALKKLLPEDLWGPINGSMVEFGRRICKPQNPLCEECFLKNHCEFYRRRGKGEVRNRTER
What is the function of this protein?
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity.  The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site.  The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
What are the official names of this protein?
Endonuclease III, DNA-(apurinic or apyrimidinic site) lyase.
What is the protein family that this protein belongs to?
Belongs to the Nth/MutY family.
Protein: UVRC_STAA8
Sequence: MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDKLCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_ECODH
Sequence: MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIVAQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RRP8_MOUSE
Sequence: MFEEPEWVEAAPAIVGLGAATAQVRPATAPPVKGRKRRHLLATLRALEAASLSQQTPSLPGSDSEEEEEVGRKKRHLQRPSLASVSKEVGKKRKGKCQKQAPSISDSEGKEIRRKCHRQAPPLGGVSAGEEKGKRKCQEYSSLHLTQPLDSVDQTVHNSRTSTATIDPSKPSPESMSPNSSHTLSRKQWRNRQKNKRRHKNKFRPLQTPEQAPPKASIEETEVPPVPKSDSQESRAGALRARMTQRLDGARFRYLNEQLYSGPSSAARRLFQEDPEAFLLYHRGFQRQVKKWPLHPVDRIAKDLRQKPASLVVADFGCGDCRLASSVRNPVHCFDLASLDPRVTVCDMAQVPLEDESVDVAVFCLSLMGTNIRDFLEEANRVLKTGGLLKVAEVSSRFEDIRTFLGAVTKLGFKIIYKDLTNSHFFLFDFEKTGPPRVGPKAQLSGLKLQPCLYKRR
What is the function of this protein?
Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes.  The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.  In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.  Its substrates are however unknown (By similarity).
What are the official names of this protein?
Ribosomal RNA-processing protein 8, Cerebral protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RRP8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Localizes at rDNA locus.
Protein: RS9_NOSP7
Sequence: MVVADANSGRAVYWGTGRRKNAVARVRLVPGTGQLTVNGKDGNLYFQFNPNYLGVIKAPLETLGLENEYDILVKAEGGGLTGQADSVRLGVARALCQLDPDNRPPLKTEGYLTRDPRAKERKKYGLHKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.