PharMolix/UniProtQA huggingface dataset:
Protein: YCX7_EUGLO
Sequence: MNRKDIKDILIKLLVIHACVTFVFAITFLMCNVEAAIILKSLSIFTKCKYFYDNIYIIFYNIFYCIKLYFINFFVF
What are the official names of this protein?
Uncharacterized 9.2 kDa protein in rpl23-rpl2 intergenic region, ORF76.
What are the subcellular locations of this protein?
Plastid.
Protein: LEUC_BURP6
Sequence: MAQTLYDKLWNSHVVHTEEDGTALLYIDRQLLHEVTSPQAFEGLKLAQRPVWRISANLAVSDHNVPTTDRSHGIADPVSKLQVDTLDANCDAYGITQFKMNDVRQGIVHIIGPEQGATLPGMTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLLQKKSKNMLVKVEGQLPRGCTAKDIVLAIIGRIGTAGGTGYAIEFGGSTIRALTMEGRMTVCNMAIEAGARAGMVAVDDTTVEYLKGRPFVPTGAEWDQAVEYWKTFRSDEGAQFDRVVELDAAQIVPQVTWGTSPEMVTSIDGRVPDPEREKDPVKRDAMERALAYMALAPNTPIEAIKVDKIFIGSCTNARIEDIRAAAYVVKKLNRRVAPNVRLAMVVPGSGLVKAQAEREGLDKVFTEAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAAIEGHFVDIRRLG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL24_THEAB
Sequence: MARKIRKGDTVMVLSGKDKGKTGEVVRVIPKEDKVVVRGVNVVKRHQRPNAQMRQGGIIEKESPIYACKVALVCPSCGKATRVGFRFLEDGTKVRYCKKCGEVIDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS8_MACCJ
Sequence: MTMSDPIADMLTRVRNANMVRHEKLELPASNIKKEIAEILKREGFVKSVEYIEDDKQGVIRMFLKYGANNERVITGLKRISKPGLRVYAKADELPKVLNGLGIALVSTSEGVLTDKEARQRNIGGEVLAYIW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NOP58_NEOFI
Sequence: MTLFILTETSAGYALLKAKDKKLLKRDDLATEASTAEGVSNLVKLKSFQKFDSAATALEEVASLVEGKVTPRLASLLDEIKDEKKVSLAVADPKLGNAIGKLPGMSIQLVADSTTTDIFRAIREHLPTLIPGLLPQDMSTMSLGLSHSLARHKLKFSPDKIDTMIVQAIGLLDDLDKELNTYAMRVKEWYGWHFPELAKILNDNIAYAKLVLKMGMRSNWETADLAEILPEELEGTVKAAADRSMGTEISQEDLENIQALAEQVVGFAEYRQQLAGYLTARMNAIAPNLTALVGELVGARLIAHAGSLTNLSKSPASTIQILGAEKALFRALKTKHDTPKYGLIYHASLIGQATGKNKGKMARVLAAKASLGLRVDALAEWDDDATEEDKAALGTEARYNLERKLAAMEGKPLKPRGVAIGPNGASVQPKKFEINETRRYNADADALTGDQPASKKDKKLIEEVSDEEMADADSDEEPKANGTKDDDSSDESEEESSKKHKSKKGKDTELEKMAEKAGLSVKRYKRKLERGEITFDANGNPSATSKKELKKAKKEAKKASKGDEKKRKRSDDGEEADNGEKKKKKKKKGEE
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RIBL_METMS
Sequence: MTRILATGTFDILHPGHLYYLEQARKYGNELYVLVARDSTIEHKPKPIVPEKQRLEMVKALRVVDHALLGSEEDMFKPLKEVQPDIIVLGHDQVFDEKELEDKLQKRGFNTKVVRLGKPHQCTLCSSGRIIKRILERKRTEL
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: TPSY_SCHPO
Sequence: MGRQFICSIYLPYTINFHLDELEGNHESHPAITHQEKVTQTHRDSVKIDDILTRLSISKSESGQATPVLTPQLEGMNDYFSLGPSKRTGGSMTPGLGAMSPIPGSGRSSPLYTQPRSRATSPSRVRQADRFAAPGIGAGALPIRRKRRDSLAKSVALFESARWSVERGVVGNSGLFHAVDAAVRDHGLQNPLWVGLLGMPTESLSEKTKNAISGALLVKHQSLVVYTSDSNFEGHYNHYCRKILWPSLHYQHNEIFSFFHEESNWDDYVAVNRAFADALIKNYKTGDTIWVNDYHLLLVPNMVRERIPSAIIGLFIHVSFPSSEVFRCFARRKELLQGMLGSNLIGFQTEEYKRHFLQSCSRVLYAESTFDRILLDDRYIDVYAHPIGADPVLVDKWLENPETLEVKEVLEKRYANLNIFVGCDKMDPIRGIREKLLAFEQFLYDNPEYQKNTILIQTSTFTEEQKEYGVAISDIVTRINSAFGDFSLDHLPVTILSSDLSYPQYLALLSVADAFIVTSLREGMSLTCHEFILTQRQKKSPLIVSEFIGCASMFSNGAFIVNPWSTLELSLSMKKALTLSTNERNQRYSNCLDVVLTHSASNWVTGFETKLKKSWTSQQKRDFSRLPRFTLNFIGNRYDHAKKRLLILNFDGNAVTWEGRHEFVDFHYGYMVSILSKLIADDRNIVYIASCLEEDELESLFMHVPGVGLIAENGCYVLPHYAENVHQSWIRLYKKQQMDWREPLHDIIQYYSERTPGSSLIDHGFAMEFNYVKAENRENGLRSAGELASSINETQHGCRAVPLDGRVLCEPTTISKATAANYIMTHLIKNPEELDLILVAGNNRTDESVFAWANKSKVSSFTVSMGVGNTEAKAYTDGIPSFFNVLNSLCA
What are the official names of this protein?
Putative alpha,alpha-trehalose-phosphate synthase [UDP-forming] 100 kDa subunit, Trehalose-6-phosphate synthase, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the glycosyltransferase 20 family.
Protein: EFP_HELPJ
Sequence: MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDTYQFMDIESYEQIALNDSQVGEASKWMLDGMQVQVLLHNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVVQVPFHVLEGETIKVNTETEEYLEKVK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_LEGPH
Sequence: MMQRKIKSYVLRAGRISNRQQQGLDLWLEDYELKFDSPTPWNFAKEFGRHDADTIVEIGFGMGTSLFAMAMNNPQCNYLGIEVHKAGVGSLVADLHEYQISNVRVVVHDAVEVLQTKIPENSLAGVQIFFPDPWHKKRHHKRRLIQSEFIQMLVKKIRPSGFIHCATDWEDYAEHILNVLSSESALFNQQKEGGYSPRPDSRPLTKFELRGERLGHGVWDLVFIKK
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: DPOE_DEBHA
Sequence: MPSKYGNGSGTGRFVKNSTIKSEFRNNGYNRAEVIDPSIANNPMLNDSIQKRELVNRIDQLDSIMGFDRIEHGEMDGAKPRRGWLVNMHATTIPTDEYLAGYSGVDYYFLDEEGGSFKATIRYDPYFYLVVIPGHESEVEEMLRKVLEPCSLKGLLRVAKEDLSLPNHLVGLKKTLVKLSFHNVVDLLSARRLLNPIIKDNKMKRDTRDIYQVMNFNNVNNANGTEIQTNFNDKSTEQIADPATLIDDIREYDVPYHVRVSIDEKIRVGKWYNVFVKHSEVRLEEDKEKIAFADPVILAFDIETTKAPLKFPDAKTDQIMMISYMIDGEGFLITNREIISEDIEDFEYTPKPEYPGLFTIFNEPDEKMVLVRFFEHIRDSRPTVIATFNGDFFDWPFVEKRTTFHDMDMFEEIGFAKDNEGEYKSKYCVHMDCYRWVKRDSYLPQGSQGLKAVTTAKLGYNPTELDPELMTPYAYEKPQLLSEYSVSDAVATYYLYYKYVHPFIFSLCTIIPLNPDEVLRKGTGTLCEMLLMVQAYENGIVLPNKHTEPIERFYDGHLLESETYVGGHVESLEAGVFRSDLPNDFKVDPTAVDEILGDLHNALKFCIEVENNKKVEDVENYDEVYNQIKDSLVNLRETPIRHENPLIFHVDVASMYPNIMTSNRLQPDSMKSEEDCAACDFNRPGKNCDRRLPWSWRGEYYPAEMNEYGMIKRTLQNETFPPAKPWLPAKTFDELSYSEQASLIKKRLSDYSRKVYHRIKQSKTVSREAIVCQRENPFYVDTVRSFRDRRYEFKTLVKVWKGKTAKIDKHDTIAKDEAKKMVVLYDSLQLAHKVILNSFYGYVMRKGSRWYSMEMAGITCLTGATIIQMARSLVERLGRPLELDTDGIWCILPKSFPENYYFKCKDGKNIFLEYPCSMLNYLVHDKFTNHQYQDLVDPNTFKYKTRSENSIFFEVDGPYKAMVLPTSKEEGKGLKKRYAVFNDDGSLAELKGFELKRRGELQLIKNFQSDIFKLFLDGDSLENCYKSVATVANNWLDVLDTKGGMLEDEDLIELICENRSMSKSLAEYGNQKSTSITTAKRLGEFLGEEMIKDAGLACKYIISSKPIGSPVTERAVPVSIFSSEKKEFFLKKWLKDPSLENFDPRSVIDWNYYYERLASVVQKIISIPAALQDIKNPVPRVPHPEWLQKKINSKEDSKQQSSISSFFGQATKKEVLQKSIKSIQDIEDFGELDASIPKGRVSKVTSRKRRNGKANNVSDSEEEERNNAILNGECPSMTEDYAGFLQYQKAKWKVQEKNRERRKKLFGSNAESSHRSSVGGIIRRQAENIAGSDWEILEYKADPSKPGDIKVYVSASNKVHSFTFHVPKKVYASFKTELSPKKAIRNCEIEKSTAVLPNGHDGSNLYKLTMPEETYLEESTKVESLLQDSNILGLYETQVGAVERAIIDLGNNIRFDDTKVGALGKGLKNGFNVKDLMKVERDSYLKRFGMDIIYFLHLVTNSYEFFTIFKSWENTASIFVLKPSANAQELPSNMDKIYREIFEAKKDRLGKMYSIIEYPDEMKFETTYFHDTAKIFKKMDNCISKIYESRSNRALLAVQSPYTTKVLNLLKSTSSFPTIKMNVSELSLPAVGWQSLIIKRVVNHYFVLASWIKKLISLAKYGNVPLCNLQIENMGYLIDIEYARRLSQSNIVLWLSSRPLPDHGGFEMDKAQDFENLEFPTINNPEIYETACLEVEIGTLTINTILTSALINEAEGTDLADDAVQFDNNNGASTIAEDSFSTPALSILRGMVKDWWDDALKNNDNADSMMNNLVTWVQRSDSLLYDYSLHYHVHNLTTKALLQLIGEFKRMNAQVIFANRNKMLIQTTKVSIENSYAYGQYILKAARSKPLFNFLDLRIVKYWDLLVWMDEYNFGGRCCTEITNDEVQNLIPVNKWQITKFLPVIFQNEFEDWLIIFLDSLTKFKNDTLIPGTQTGTPRVTQIAHILKGQKKLDSNETEEESISNGVMELFRKPLQKRIEKLARRQNESILNPELRQEYEFPKLPGSYTSMKNPSLELVKFLCAVFGLSRKRNIEVRLLRRELLSIFDIKEFSDEAAFKNPSSSLKIPHVICDYCNYIRDIDFCRDEQKNIWNCSNCNKTYNRVAIEEELVAQYNKLLTKFYIQDLKCSKCHQIKSDNMSEYCKCSGKWTETLKYTEVDKRLQIFSNVGGFFNLQLLKGIIEELAL
What is the function of this protein?
DNA polymerase II participates in chromosomal DNA replication.
What are the official names of this protein?
DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KHTU_BACSU
Sequence: MDHLVFEVGTALVLVAIASVIANKIKFSIIPFLIVLGMLVGPHAPKMGIIDLTFIQSSEIIEFFGRMGVLFLLFYLGLEFSVGKLIKSGKSIAVGGTIYILINFSLGLLYGFITGFSFLEVLILAGVITISSSAIVAKVLVDLKRTANPETELILGIIMFEDIFLAVYLSVVSGLILGDATSVGSALLSILIAFGYMLLFFIAARKLPPLLNKLLDIRSNEVFIIVIFAALFFIAGFSETIHVAEAIGALLLGLVFSETEHSDRIEHLVVPFRDFFGAMFFFSFGLSIDPFSLGEAVWLALGAVILTILGNFIAGMVAGRRAGLSHKASSNIGLTIVSRGEFSIIVANLGIAGGLSATLKPFAALYVLILAILGPLVTKESKRIYRLLNKVFKWKPEVQPAKKQG
What is the function of this protein?
Potassium/proton antiporter that mediates the efflux of potassium ions from the cell (PubMed:17679694).  Can also mediate rubidium/proton antiport, but has no permeability for sodium or lithium ions.  In the absence of KhtT, does not have antiport activity, but can catalyze potassium efflux (PubMed:14987767, PubMed:17679694).  Involved in protection of the cell from methylglyoxal, a toxic by-product of glycolysis, via activation by S-lactoyl-BSH of the antiporter activity, leading to cytoplasmic acidification and methylglyoxal resistance (PubMed:24330391).
What are the official names of this protein?
K(+)/H(+) antiporter subunit KhtU.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G3P1_STRAW
Sequence: MTVRVGINGFGRIGRNVFRAAATRGADLEIVAVNDLGDVATMAHLLAYDSILGRFPEEVTAEPGAIRAGDTTVKVLAERDPAALPWGDLGVDVVIESTGIFTDAAKARAHVDGGAKKVIIAAPASNEDVTVVLGVNQDAYDPERHTIISNASCTTNCLGVLAKVLHDAVGIESGMMTTVHAYTQDQNLQDAPHKDLRRARAAGLNIVPTSSGAAKAIGLVLPELQGRLDAFALRVPVPTGSVTDLTVTASRSTTVEEVKEAYAKAAAGAYKGLLSYTEAPIVSTDIAGDPASCVFDAELTRVLGSQVKVVGWYDNEWGYSNRLIDLALLVGDTL
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, GAPDH 1, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase, PL-insensitive glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_BACTN
Sequence: MLRIAVQAKGRLFEETMALLGESDIKISTTKRTLLVQSSNFPIEVLFLRDDDIPQTVATGVADLGIVGENEFMEKEEDAEIIKRLGFSKCRLSLAMPKDIEYPGLSWFNGKKIATSYPVILRNFLKKNGVNAEIHVITGSVEVSPGIGLADAIFDIVSSGSTLVSNRLKEVEVVMKSEALLIGNKNMSDEKKEVLEELLFRMNAVKTAEDKKYVLMNAPKDKLEEIIAVLPGMKSPTIMPLAQEGWCSVHTVLDEKRFWEIIGKLKGLGAEGILVLPIEKMIV
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP1M1_MOUSE
Sequence: MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ
What is the function of this protein?
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes.  The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
What are the official names of this protein?
AP-1 complex subunit mu-1, AP-mu chain family member mu1A, Adaptor protein complex AP-1 subunit mu-1, Adaptor-related protein complex 1 subunit mu-1, Clathrin assembly protein complex 1 mu-1 medium chain 1, Clathrin coat assembly protein AP47, Clathrin coat-associated protein AP47, Golgi adaptor HA1/AP1 adaptin mu-1 subunit, Mu-adaptin 1, Mu1A-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes medium subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle, clathrin- coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: Y215_LISIN
Sequence: MNIMIALIPALLWGTVPLIITKFGGSTRQQTMGMTLGALTFAVIVFFFTDPVYTLKTVGISFITGCLWTVGQMFQLRAFKIIGVSKAMPISTGMQLVGTTLCGVILFHEWDTTLRIILGFIALALIVGGIFLTSYAEKEEDGTNALKQGLITLVISSLGYVGLVVLIQGFKIDGINAILPQAIGMVLSALIMTHSGGTEKRFNKRTLLLIIPGMIWAAGNVAMVHANQLVGVATGFSLSQLGVVISTIGGIVLLKEKKTQKEMLYVIVGVVLVVLGGILIGVAKGA
What are the official names of this protein?
Putative sugar uptake protein lin0215.
What is the protein family that this protein belongs to?
Belongs to the GRP transporter (TC 2.A.7.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HABP2_MOUSE
Sequence: MFVRMLVFRVLLLIALVGKSVIGLSLMSFIAPPDPDWTPDDYYYSYEQSSPDEDPSVTQTTPENPDWYYEDDDPCQSNPCEHGGDCIIRGDTFSCSCPAPFSGSRCQTAQNKCKDNPCVHGDCLITQKHPYYRCACKYPYTGPDCSKVLPACRPNPCQNGGVCSRHRRRSRFTCACPDQYKGKFCEIGPDDCYVGDGYSYRGKVSKTVNQNPCLYWNSHLLLQETYNMFMEDAETHGIAEHNFCRNPDGDHKPWCFVKVNSEKVKWEYCDVTVCPVPDTPNPVESLLEPVMELPGFESCGKTEVAEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGALIHPCWVLTAAHCTDINTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALESRYVKTVCLPSDPFPSGTECHISGWGVTETGEGSRQLLDAKVKLIANPLCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECGKKPGVYTQVTKFLNWIKTTMHREAGL
What is the function of this protein?
Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly.  It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form.  Activates coagulation factor VII (By similarity).
What are the official names of this protein?
Hyaluronan-binding protein 2, Plasma hyaluronan-binding protein.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted as an inactive single- chain precursor and is then activated to a heterodimeric form.
Protein: Y1733_ARATH
Sequence: MSSDIPCCGTTFSLYVVIIIALVAFAGLMAGLTLGLMSLGLVDLEVLIKSGRPQDRINAGKIFPVVKNQHLLLCTLLIGNSMAMEALPIFLDKIVPPWLAILLSVTLILVFGEIMPQAVCTRYGLKVGAIMAPFVRVLLVLFFPISYPISKVLDWMLGKGHGVLLRRAELKTFVNFHGNEAGKGGDLTTDETSIITGALELTEKTAKDAMTPISNAFSLELDTPLNLETLNTIMSVGHSRVPVYFRNPTHIIGLILVKNLLAVDARKEVPLRKMSMRKIPRVSETMPLYDILNEFQKGHSHIAVVYKDLDEQEQSPETSENGIERRKNKKTKDELFKDSCRKPKAQFEVSEKEVFKIETGDAKSGKSENGEEQQGSGKTSLLAAPAKKRHRGCSFCILDIENTPIPDFPTNEEVVGVITMEDVIEELLQEEILDETDEYVNIHNRIRVNMHASPENLPSVITSITQSSSGSTSPNQTSHMATPDSSPTTKPSNSSPTRKPSVSSPTREPSDSSHSMAPKHEESTQTL
What are the official names of this protein?
DUF21 domain-containing protein At1g47330, CBS domain-containing protein CBSDUF7.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GATA5_MOUSE
Sequence: MYQSLALAQSPGQGTYADSGAFLHSSGTGSPVFVAPTRMPSMLPYLPSCEPGSQAPALAAHSSWTQAVAADSSAFGSGSPHPPAAHPPGATTFPFAHSPPGSGSGGSAGVRDGGAFQGALLAREQYPTPLGRPMGASYPTTYPAYMSSDVAPSWTSGAFDSSILHGLQARPGGLPGRRTSFVPDFLEEFPGEGRECVNCGALSTPLWRRDGTGHYLCNACGLYHKMNGVNRPLVRPQKRLSSSRRSGLCCSNCHTATTTLWRRNSEGEPVCNACGLYMKLHGVPRPLAMKKESIQTRKRKPKNPAKIKGSSGSTANTTASSPTLLNSESSATTLKAESSLASPVCAGPTITSQASSPADESLASSHLEFKFEPEDFAFTSSSMSPQAGLSGVLRQETWCALALA
What is the function of this protein?
Transcription factor required during cardiovascular development (By similarity).  Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (PubMed:9119112).  Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (By similarity).
What are the official names of this protein?
Transcription factor GATA-5, GATA-binding factor 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL7_ECOL6
Sequence: MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12, L8.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: NA123_ANEVI
Sequence: MMNRLLVFLMLGAAFMLVVSAIDQDANEDINKRGVPCLCDSDGPSVRGNTLSGIIWLAGCPSGWHNCKKHGPTIGWCCKQ
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation during signal transduction (By similarity).  Has a strong effect on crustaceans and insects and a weaker effect on mammals (By similarity).  It strongly inhibits D. melanogaster sodium channel (DmNav1) (By similarity).  It strongly affects the heart sodium channels (Nav1. 5/SCN5A) and weakly inhibits the brain sodium channel Nav1. 2/SCN2A (By similarity).  In vivo, when released into the medium, this recombinant toxin induces impaired swimming, paralysis and death of the crustacean A. nauplii within several hours (PubMed:22048953).  Its effect on zebrafish (D. rerio) larvae is much faster, since it induces paralysis or strong convulsion and impaired swimming, within 10 minutes (PubMed:22048953).
What are the official names of this protein?
Delta-actitoxin-Avd1c 3, Delta-AITX-Avd1c 3, Anemonia viridis toxin 2, Av2, Avt 2, Toxin Av2-3.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Note=In nematocyst, is associated with the tubule prior to discharge.
Protein: YM046_YEAST
Sequence: MESIFLHTNITIIPHSVLYVSLSYYIINPCTSASSNFDDSFS
What are the official names of this protein?
Putative uncharacterized membrane protein YMR046W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EFTU_PHATC
Sequence: MAREKFERTKPHVNIGTIGHVDHGKTTLTAAITATLALDGGAQAKAYADIDGAPEERARGITINTAHVEYETKDRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSKQVGVPNIVVFLNKEDQVDDEELLELVELEVRELLSAYDFPGDDIPICPGSALQAIEAITANPTVKRGDNKWVDKIYALMDAVDEYIPTPERDVEKTFLMAIEDVFSITGRGTVATGRIERGVVKVGENVEIVGVTDTQTTTITGIEMFQKTLEEGFAGDNVGILLRGVTRENIERGMVLAKPGTITPHTSFESEVYVLTKDEGGRHTPFFTGYRPQFYVRTTDVTGSITQFTADDGSVVEMVMPGDRIKMTAEFIYPVAIEAGMRFAIREGGRTIGAGVVSKIVK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, chloroplastic, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TREA_EMENI
Sequence: MRFKSVFTLLPLLAQLPSGGASLPNNHGRVENCVRNHDGIHKFRHSNNTYQSMFPGVTWDEDQWVLTTSSLDQGHYQSRGSVANGYIGISVSSVGPFFELDLPVAGDVINGWPLYSRRQSFATISGFFDIQAETNGSNFPWMNQYGGESVISGVPHWSGLILDLGDDDYLDSTVDNVTLSDFKSSYDFKAGVLSWSYTWTPAGDKGSYAITYRLFANKLNVNQAVVDMEITPSQDGHATIVNVLDGYSAVRTDFVESQEDDGAIYSAVRPWGIPDVSAYFYANITGSKHVDLSSRRLIHGKPYVSANESSIAQAADVNFVANEKVRITKFVGAASTDAFPDPQATAKRAVSEALDAGYQRSLRSHVQEWASIMHEDSVDRYVNPTTGKLPDDDNIINSAIIAVANTYYLLQNTVGKNAIRAAQDAPLNVNSFSVGGLVSDSYAGLVFWDADVWMQPGLVASHPEAAQAVTNYRTKLYPQAKKNIETTYTGSKNATYIDPSAAIYPWTSGRFGNCTGTGACWDYQYHLNGDIGLSLIYQWVVSGDTNTFREKHFPIYDSVAALYGSIVERNGSYWTLTNMTDPDEYANHIDAGGFTMPMISETLEYANQFRQQFGLEPNETWTEISENVLVLRENGVTLEYTTMNGTAAVKQADIVLVTYPLVYDNYTAETALTDLDYYANRQSADGPAMTWAIFSIAAGAVSPSGCSAYTYHQYSYAPYARAPFFQLSEQMLDNASINGGTHPAYPFLTGHGGANQVVLFGYLGLRLLPDDAIHIEPNLPPQIPYVKYRTFYWRGWPISAQSNYTHTVLQRSQSAPLDTADRRFANTSIPVFVGLADNATLHHLPPHGPLTVRNREIGTINTIEDNLIQCSPVSSTDAFEQGQFPISVVDGATSTRWQPSSSNASAVTVNLGSTTGRSVQTVASGFHFDWAAAPPVNASVIFHDTPLSDPVAALSSPGPHVRIVANLTNIEQSGPYDPEATDLNEIKIPVGNTTRIELAQEVPVGRYATLVISGNQALAQADGEDHVGATVAEWAILGPKSGSPRRRIQPVPLL
What are the official names of this protein?
Acid trehalase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 65 family.
Protein: EMX2_HUMAN
Sequence: MFQPAPKRCFTIESLVAKDSPLPASRSEDPIRPAALSYANSSPINPFLNGFHSAAAAAAGRGVYSNPDLVFAEAVSHPPNPAVPVHPVPPPHALAAHPLPSSHSPHPLFASQQRDPSTFYPWLIHRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAHSLSLTETQVKVWFQNRRTKFKRQKLEEEGSDSQQKKKGTHHINRWRIATKQASPEEIDVTSDD
What is the function of this protein?
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain.  May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.
What are the official names of this protein?
Homeobox protein EMX2, Empty spiracles homolog 2, Empty spiracles-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the EMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.