PharMolix/UniProtQA huggingface dataset:
Protein: COX2_GERGE
Sequence: MAYPFQLGLQDASSPIMEELMNFHDHTLMIVFLISSLVLYLMALMLSTKLIHTSTMDAQEVETIWTILPAIILIMIALPSLRILYMMDEINNPILTVKTMGHQWYWSYEYTDYEDLCFDSYMIPTNELKPGELRLLEVDNRIVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATITSNRPGVFYGQCSEICGSNHSFMPIVLEMIPLKLFENWSMSMT
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MOBA_SALTI
Sequence: MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALAPQLATVVISANRHLDIYQASGLKVIPDSIADFPGPLAGMLSVFQQVAGDWFLFCPCDNPCIPHNLVDRLAAHRHGAPVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIFMRQVGGHAVDFSDCKEAFVNVNTPEELAQWQKRP
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYOE_PSE14
Sequence: MSLKHFIQITKPGIIFGNVLSVAGGFFLASKGNIDFGVFLAAVIGTSLVVASGCVFNNCIDRDIDQRMERTRNRVLVQGLVSLKLALLYATILGVAGVALLYTEANPLAALFAVIGFVIYVGLYSLYLKRRSVHGTLVGSLSGAMPPVIGYCAVTNSFDFAALTLLVMFSLWQMPHSYAIAIFRFNDYRAAKIPVLPVKRGILVTKRHIMLYILAFLVATLMLTVGGYAGLNYLAVAAGMGMYWLYMAWKGYKAVDDTVWARKLFVFSIFTITALSVMMSVDFQVTKELLVTYAF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YQGF_DESHY
Sequence: MRIMGLDFGERTIGVAVSDAMLLTAQGVKTIRRSPKELEELKTMLQDYEVDHIVLGYPKNMNGTLGPRAQATEEFAQILKEEFGLPVTLWDERLSTMGAQRSLLEADVSRAKRKQVIDKMAAVFILQGYLDYIRQKNGQNKE
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_SYNC1
Sequence: MLDLKFVRDHFAEAEQRLATRGGAVDLSAFTDLDARRRTLLGESESLKAEKNQVSALIGKTKDKSQVQGEIARMKDVSVRIKELDEELKQVEGDLRTLLMTLPNLPHEDCPVGTSEDDNKEVRRWGQVPEFDFEAQSHWDIGERLDILDFERAGKLAGARFAIYKGAGARLERALINFMLDLHTGEHKYVEILPPLMVNRDTMTGTGQLPKFESDLFHLDDPDFFLIPTAEVPVTNIHRDEILADGDLPVCYAAYTPCFRKEAGSHGRDTRGLIRMHQFNKVELVKFARPEESDQELLKLLDNAEEVLRRLKLPYRVVDLCTGDIGFSAARTFDIEVWLPGQQTFREISSCSNFRDFQARRAAIRFRREEKGKPELVHTLNGSGLAVGRTLVAILENYQQEDGSVVIPEALRPYMGGVEKISA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP8_RRSVT
Sequence: MNTKGFAQKIQRTFHLIHQSHYTPPPNKISTHVEIFSELLTYVDYEWQRAAIGASRWVELAAEENEIHIPFNTKDERQVNFLIAIIHVAISLYSNSGVEPFADCDLEKILNGDYESSKFDWNVVFDIVLPNDVRLKEKTLKAAVVEEERVEPRPKRREITLGGQRPLQTRDVRSDSDLIVLSKLEAYDDVVERPRQNNTDIIIHRLGLAKMNPASNSILPAKISRIITEQVFGAGVNVDYIARPTEGFISLSTATYTVASYFERGIANYDINAVLDNIIDKTDQLNTTDTVVELPSIPPEDSSIEVATPSHETFFDINTMIYIIMCCGSITNPMIQRLNGIVTRYNTTNYVVSYPDTDDGRKKALAERAVITVDGKYYKCYNDIKADTDKRRILNPAVIKEVMISLRHYCGSVIHYRERMEATHISQVFCLLMGICYGGLDTKKIRCRWFEWPAVSNVPVTSSYAEFKGSNSGLPPYQCRKFTPRTVMTSFAHWNLWAWMLDLAIDKRMSSDRHLSIMKIYVLNAFSHLVLNSSLENSANILGPFPSFSGYTAFTSTSIVRDVSSCQRLAPFLLRMFSLVDYVAAAASSEASGSGV
What is the function of this protein?
120 subunits of the putative clamp protein VP8b appear to stabilize the capsid shell.
What are the official names of this protein?
Structural protein precursor VP8.
What are the subcellular locations of this protein?
[Putative clamp protein VP8]: Virion.
Protein: RF2_STRM5
Sequence: MIELNPVRQRITDLTDRVLSLRGYLDYDAKKERLEEVTRELESPDVWNNAEYAQNLGRERSSLEKTVGGIASVLDGLADATELLELAESEQDEDTALAVVADLDKHQAHVEKLEFQRMFSGEMDNAAAFVDIQAGAGGTEAQDWAEILLRMYLRWCESRGWKTELMEVSGGDVAGIKSATLRVEGDYAYGWLKTETGVHRLVRKSPFDSDNRRHTSFTSVFVSPEIDDNIDITINPADLRTDVYRSSGAGGQHVNKTESAVRITHIPTNIVVACQTGRSQHQNRDNAMKMLAAKLYELEIQKRNAEKDAVEATKSDIGWGSQIRNYVLDQSRIKDLRTGIERSDTQKVLDGDLDEFVEASLKAGLAVGSKRVDA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GVPA_NOSP7
Sequence: MAVEKVNSSSSLAEVIDRILDKGIVIDAWVRVSLVGIELLSIEARIVIASVETYLRYAEAVGLTSQAAVPSAA
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  GvpA type proteins form the essential core of the structure.
What are the official names of this protein?
Gas vesicle structural protein, GVP.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle membrane.
Protein: SYN_PSYIN
Sequence: MSKTAIVEIFNSKFPIGTEVTVQGWIRTRRDSKAGISFLAIYDGSCFDPIQAVVPAALENYSDEVLNLTAGCSVQVTGELVESPGKGQQFEIQATQVEVLGFVQDPDTYPMSAKRHSIEYMREHAHLRARTNMFGAVTRVRNCLSHAMHNFFYEKGFNWISTPIITGSDAEGAGEMFRVSTLDLENLPRNDTGAIDYKKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHTTRHLAEFWMVEPEIAFADLADAAQLAEDMLKYVFNAVLTERADDMAFFAQRVDKEAITRLEKIVSSEFVRMDYTDAIEILQNCGKEFEFPVAWGVDLQSEHERYLAEVHVGAPVILQNYPKDIKAFYMKLNADGKTVAAMDVLAPGIGEIIGGSQREEDLVALDKRFDEMGINKEDYSWYRDLRKYGTVPHAGFGLGFERLVSYVTGVQNIRDVIAFPRAPGSADF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_LAWIP
Sequence: MKTFSPKPEHISHQWFLVDAHNKILGRLAAQIAHRLRGKHKPEFAPHIDNGDYIVVVNCEQIKVTGNKQEQKKYYRHSGYVGGLKETTLKTLLEKKPAEVLIHAVRGMLPKNRLGRAMLKKLKVYAGPEHQHIAQQPIPLSLPY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: DUT_PSE14
Sequence: MHALQAKILDPRIGNEFPLPAYATVGSAGLDLRAMLKEDTVLEPGQTLLIPTGLSIYIGDPGLAALILPRSGLGHKHGIVLGNLVGLIDSDYQGELMVSCWNRGQTAFNIAVGERIAQLVLVPVVQAHFELVEAFDESQRGAGGFGHSGSH
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: TRUB_SYNY3
Sequence: MFGFLNLHKPLHLTSHDCVAKVRRLLRQKRVGHGGTLDPLAEGVLPLAVGSATRLLPYLPGAKQYQALIRFGVRTDSDDLAGEVLESKNVSYLTLAAVEQILPTFLGEIEQIPPQYSAIQVNGKRLYELARAGIPQAVPSRMVTINDLKILGWRSGNQPELDLQVTCGEGTYIRALARDLGDRLGTGATLAGLVRQQSGGMALDNSVGLTALEKIVAEEEHIPLIPPQEALSHLPTVQLNSELEKRWFHGQRLLLPDLPVGVVLITSELGPVKCLGVALVTPEDHGTVLRPKVVLN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RIMM_PSEP1
Sequence: MNATPEKADDLIVVGKIFSVHGVRGEVKVYSFTDPIENLLDYPRWTLRHEGKVKQVELVSGRGSQKGLVVKLKGLDDRDEARLLSGYEICIPRSLLPNLAADEYYWYQLVGLKVINQDEQLFGKVDHMLETGANDVMVVKPCAGSLDDRERLLPYTEQCVLAIDLEAGVMRVEWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHTA_SALTS
Sequence: MPGSTRKLPVWLPILVLLIAMSSIQSGASLAKSLFPLVGAPGVTALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGLSLGGMNYLFYLSIQTVPLGIAVALEFTGPLAVALFSSRRPVDFIWVVLAVLGLWFLLPLGQDMSHVDLTGAALALGAGACWAVYILTGQRAGAEHGPATVAVGSLIAAIIFVPIGAVQAGDALWHWSILPLGLAVAVLSTALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTGIQILALCAIIAASMGSTLTIRREPQIKQVDVK
What is the function of this protein?
Involved in the efflux of threonine and homoserine.
What are the official names of this protein?
Threonine/homoserine exporter RhtA.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. 10 TMS drug/metabolite exporter (DME) (TC 2.A.7.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COAE_PSEU2
Sequence: MTHPDEKPWILGLTGGIGSGKSAAAKCFSDLGIDTVDADHAARWVVEPGRPALEQIAAHFGKGVLQTSGELDRGALRKLIFETPEQRRWLEALLHPLINQEIVSHLAKAKSPYAILVSPLLVESGQYRMVQRLLVIDAPAHLQIERTMLRDSSSQEQVEAILKVQIQREDRLRHANDVLVNDRDHAWLSSEVERLHHFYLTLRGGQS
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSL_ECO57
Sequence: MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATEKLQMQHVDPSQENIVVQK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: H2AZ_DICDI
Sequence: MTESETTSKKVNKRVKPVPKSTKAGLIFPVGRIHRMLKNKVPLKRVSILSSVYLAAILEYLASEVLELTISQVSIQSKEYHNVRRISPRHLLLAIKTDEELDNLIRVSTTIAGGGVIPYIHEVLKKVEQKPTHPQQKQTIKSI
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
What are the official names of this protein?
Histone H2A.z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TSAD_STRZP
Sequence: MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGGVVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFAWAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETRDDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANKGLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDTME
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX9_HUMAN
Sequence: MPDIIWVFPPQAEAEEDCHSDTVRADDDEENESPAETDLQAQLQMFRAQWMFELAPGVSSSNLENRPCRAARGSLQKTSADTKGKQEQAKEEKARELFLKAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSPDGDGVGNSYIEDNDDDSKMADLLSYFQQQLTFQESVLKLCQPELESSQIHISVLPMEVLMYIFRWVVSSDLDLRSLEQLSLVCRGFYICARDPEIWRLACLKVWGRSCIKLVPYTSWREMFLERPRVRFDGVYISKTTYIRQGEQSLDGFYRAWHQVEYYRYIRFFPDGHVMMLTTPEEPQSIVPRLRTRNTRTDAILLGHYRLSQDTDNQTKVFAVITKKKEEKPLDYKYRYFRRVPVQEADQSFHVGLQLCSSGHQRFNKLIWIHHSCHITYKSTGETAVSAFEIDKMYTPLFFARVRSYTAFSERPL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability (PubMed:34480022, PubMed:23263282).  Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation.  In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex.  As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1 (PubMed:23263282).  Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway (PubMed:34480022).  Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation (By similarity).
What are the official names of this protein?
F-box only protein 9, Cross-immune reaction antigen 1, Renal carcinoma antigen NY-REN-57.
Protein: TPX_SHIFL
Sequence: MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNNVITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYEAALAVLKA
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Thiol peroxidase, Tpx, Peroxiredoxin tpx, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Tpx subfamily.
Protein: RLMN_BURP6
Sequence: MAGETIVNLLDLDAEGLVAYCGSLGEKAFRAKQLQRWIHQYNAADFDGMTDLAKSLREKLKGRAVIGTPDILSDHVSADGTRKWLINVGNGNAVETVFIPEETRGTLCVSSQAGCAVNCRFCSTGKQGFSRNLSTGEIVGQLRMAEFALRASLGRAPGPNGKAERVITNVVMMGMGEPLLNYSAVVPAMRLMLDDNAYGLSRRRVTLSTSGVVPMMDRLGAELPVALAVSLHAPNDALRDELVPLNKKHPLRELMAACQRYLKVAPRDFITFEYCMLDGVNDTEAHARELLAVTRDVPCKFNLIPFNPFPESGLVRSKTEQIKRFAQVLIDAGVVTTIRKTRGDDIDAACGQLAGAVKDRTRLAERTGASKIIEVRAV
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US18_HCMVM
Sequence: MGDTASVSEHHESPTVTIVPLHRSHALVAEQQLFQWLKRFKLLMEVYHGLVWQLACTLTVCLLAWLAFPDVQGQCANGIVPALSSIVPVSTLAMLRGFAEFRPHTTNFAHLTVACLLINTGITVCTGFCGERRVIGLSFALVMVFFVLCSGLTYLAGNNPTRWKVIGIGYGWSVIVFYLLLYFSPVLWVSKIYSGLYVLVVTAASAVLIYETLDLIYQRGTLSKNSVCVSVVLYTIVMSLLNMSVAIFSGHVWVQQYAEKHGGRIDGVSLLSLL
What are the official names of this protein?
Transmembrane protein US18.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: 3MGH_BACCZ
Sequence: MQAPPSFYEGDTLEVAKKLLGQKLVHIVDGIKRSGIIVEVEAYKGPDDKAAHSYGGRRTDRTEVMFGAPGHAYVYLIYGMYHCFNVITAPVGTPQGVLIRALEPVDGIEEIKLARYNKTDITKAQYKNLTNGPGKLCRALGITLEERGVSLQSDTLHIELVPEEEHISSQYKITAGPRINIDYAEEAVHYPWRFYYEGHPFVSKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: B3GT4_ARATH
Sequence: MSLKHHHRGLELSASKSFVSKKWTLFLCIGFFCAGILFSDRMWPEPESNVVSRDTVASDERLRLESEDCDSSKKGLKRESKDILGDVYKSPDAIQTLDKTISKLETELADARAAQESIMNGSPVSDDFKLPETVTKRKYLMVVGVNTAFSSRKRRDSVRATWMPPGEERKKLEEEKGIVMRFVIGHSSTPGGILDRAIQAEESKHGDFLRLDHVEGYLELSAKTKTYFTTAFAMWDADFYVKVDDDVHVNIATLGAELARYRMKPRVYIGCMKSGPVLAQKGVRYHEPEYWKFGEEGNKYFRHATGQLYAISRELASYISINQNVLHKYVNEDVSLGSWFLGLDVEHVDDRRLCCGTTDCEWKAQAGNICVASFDWSCSGICRSADRMKDVHRRCGEGEKALLAASF
What is the function of this protein?
Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal glycosyl residue.
What are the official names of this protein?
Probable beta-1,3-galactosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: ILVD_XANOM
Sequence: MPEYRSKTSTHGRNMAGARALWRATGMQDGDFQKPIIAIANSFTQFVPGHVHLKDLGQLVAREIERVGGVAKEFDTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPTVFVSGGPMEAGKTALAEHKLDLIDAMVIAADDSASDEKVAEFERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTVVATHADREQLFLRAGRVAVELCHRWYGGEDPTALPRGIATFEAFENAMTLDIAMGGSTNTILHLLAAAQEGEVPFGMQDIDRLSKRVPQLCKVAPNTPKYHIEDVHRAGGIMAILGELARGGLLHTTAATVHARTLADAIAHWDVTQTVDENVHTFYKAGPAGIPTQIAFSQATRWDSLDTDRSEGCIRDVAHALSQEGGLAVLYGNIARDGCVVKTAGVDESIHVFEGTARVFESQDAAVKSILADEVKAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKQCALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVRDGDKILIDIPNRGINLLISDEALASRRAEQDAKGWKPVEVRPRKVTTALKAYALLATSADKGAVRDKALLDG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ACKA_SULNB
Sequence: MKVLVLNAGSSSLKCQYFIDEESIASVTIERIGEKESYTLLTYANEKREHTSTVKNHHDAIDTLFSLLKESHIITDVTELNAVGHRIVHGGPHFSRPTLINTEVIEQIRSLIPLAPLHNPSNLEGIEVIAKVYPALKQVAVFDTAFHQTMPEYAARYPLPYDLYEEAHVRRYGFHGTSHAYVAKEAAKILQQPLETLNLITLHLGNGASATAIKKGRSIDTSMGMTPLEGLMMGSRSGDIDPAIIPYLVRTQKIDVETIDSMLNKESGLKGVCGNNDMREIIDKMDEGDEKSRLALEMYVYRIKKYIGAYSATLGHVDALVFTGGIGEHAALVREMVCEGMEYTFGIILEKKKNDSAKQEASAIHSRESRTDILVIPTDEELEIVRQTEVIVSRLS
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_BARQU
Sequence: MSALSSNRLPNRASLVTNRAFSALEGFLHVEAFSGIVLLLAAAAALIFANSQYASVYESLWHTPLGFNFGHFTLSWDLHFWVNDALMTVFFLVAGMEIRREIHEGALADFKQAILPIVSAIGGVCFPALIYLSFNFNSEHTHGWAVPTATDIAFALGILALLGKKIPANLHVILLSLAIIDDIIAVLIIAFFYSTNIDPSGLAIAIAGIALVLFFQWIGLASAWLYILPGAIIWWGLMITGVHPSLTGVILGMMTPVFPTRTLVAPLTILSNAMQILQEKNIKTDLHHISTALKKMRKGQRDMIAPVIRVQKTLHPWVAYGVMPIFAFANAGVSFANFDLSSHESFLVVLSVVIGLFIGKPLGIITASYLAVKSGLCRLPPHMTWTGILLIGFLAGIGFTMSIFVSMLAFKDIVLLDSAKIGVLCGSGLSALAGLGYGLIYIKRNKNKKVLHNLNGIK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.