PharMolix/UniProtQA huggingface dataset:
Protein: MEND_SALCH
Sequence: MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAENPAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQAGMFASHPSQTLSLPRPTQDIPARWLVSTIDNALAMLHAGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLESDKQRDWFFWRQKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTELQQAQIVVQLGSSLTGKRLLQWQATCEPEEYWVIDNIEGRLDPAHHRGRRLVAKIADWLELHPAEKRKPWCVEIPRLAELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLNALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRYHRPENWEELESALAGAWRTPAATVIELVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: ACPS_KINRD
Sequence: MIIGVGIDVVDVARFKRQVERTPLLLERLFGDGERNLPAESLAARFAAKEAVAKSLGAPVGLVWRDVVVEREDGHRPEIAVRGSAKKIADEAGVAVFHLSLSHDAGIATAMVVAESR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_DESOH
Sequence: MTSIKTIKSRAPKDYLVFALDVPTVSEAAEYVHLLKNHVGMFKVGLELFVRGGRRIIDTIHDAGGGAKIFLDLKLYDIPETVYRTMNAIAAMGVDFATVHCSGQKDMLAAAQEGADGQVGVLGVTVLTSMSADDVRDAGYGPEYIENISRLVMKRAAAAAEWGFAGIVCSPLEVSAMKERFGKGFVAVTPGIRPAKGLVSRDDQSRISTPGQAIRNGADYLVVGRPIREPDDSAAAAAAICKEIEEALK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL16_ALTMD
Sequence: MLQPKRMKFRKMHKGRNRGFAAGSTVAFGTYGLKAVGRGRMTARQIEAARRAMTRHVKRQGKIWIRVFPDKPITEKPLEVRQGKGKGNVEYWVCQIQPGRVLYEMEGVPENLAREAFELAAAKLPFKTTFVTRTVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: RHLB_YERPN
Sequence: MSKTHLTEQKFSDFALHPLVVEALENKGFQYCTPIQALALPLTLSGRDVAGQAQTGTGKTLAFLASTFHYLLSHPAEEGRQTNQPRALIMAPTRELAVQIHSDAESLSQVTGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNYINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPSVDKRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPLQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRCIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILEDFTKGDLDILVATDVAARGLHIPLVTHVFNYDLPDDCEDYVHRIGRTGRAGESGHSISLACEEYALNLPAIETYTGHSIPVSKYNSDALLTDLPAPKRLARTRTGNGPRRNSAPRRSGAPRNNRKRPG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPL_BACSU
Sequence: MANQPIDLLMQPKWRVIDQSSLGPLFDAKQSFAMDDTLCMSVGKGVSPATARSWVHHDTIVLGIQDTRLPFLQDGISLLESEGYRVIVRNSGGLAVVLDDGVLNISLIFEDEKKGIDIDKGYEAMVELMRRMLRPYNAKIEAYEIEGSYCPGSYDLSINGKKFAGISQRRVRGGVAVQIYLCADKSGSERADLIRRFYQAALKDKQNDKKGVYPEIRPETMASLSELLQKDISVQDLMFALLTELKALSTHLYSAGLSIDEEMEFEKNLVRMAERNAKVFG
What is the function of this protein?
Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes.
What are the official names of this protein?
Octanoyl-[GcvH]:protein N-octanoyltransferase, Octanoyl-[GcvH]:E2 amidotransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipL family.
Protein: BR2EF_PELRI
Sequence: GIMDTLKNLAKTAGKGALQSLVKMASCKLSGQC
What is the function of this protein?
Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.
What are the official names of this protein?
Brevinin-2Ef.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RN28_PANGI
Sequence: MRAIYIISVIIVSLSIFSWGGNARSDYPWAMFALRLQWPAGFCEVNNACDTKSLLNTFTIHGLYPYNAKGTPALYCDGTAFDVNSVSDFLAEMHLAWPSHETNTEDIQFWEHEWKKHGRCSEALLKQTDYFRTALAFRKAFDIVGLLNQEGIYPNNDLYRPKMIKEAIKKHLNAVPEIDFTKNENSEYVLTDINVCVNQQATRFVDCPTDDATDDYRLKFVRLPSKMKFADPRTNSII
What is the function of this protein?
May act as a storage protein providing a nitrogen source.  Seems to have no RNase activity although it has conserved the active site residues.
What are the official names of this protein?
Ribonuclease-like storage protein, Root 28 kDa major protein.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
Protein: CCME_ALIF1
Sequence: MNPRRKKRLGLILALFVGISATVGLMLYALNQNMDLFYTPTELVNGKPDGTKPEVGQRLRIGGMVVAGSVVRDNNSLEVSFKVADVGPQVTVIYDGILPDLFREGQGIVAQGVLVDATTIKAHEVLAKHDEEYMPPEVAEAMKKTHEPLQYTEQQKQGTGQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: MCM7_SCHPO
Sequence: MALPTIDLKIPEYEECQHKITDFLSHFKQEQVQDGQQNQDISMSDAGDEPFLKSKYMDILQKISNRESNVINVDLNDLYEFDPSDTQLLHNIESNAKRFVELFSQCADALMPPPTVEINYRNEVLDVIMQQRVQRNENIDPEHKGFPPELTRGYDLYFRPVTRNKKPFSVRDLRGENLGSLLTVRGIVTRTSDVKPSLTVNAYTCDRCGYEVFQEIRQKTFLPMSECPSDECKKNDAKGQLFMSTRASKFLPFQEVKIQELTNQVPIGHIPRSLTVHLYGAITRSVNPGDIVDISGIFLPTPYTGFRAMRAGLLTDTYLECHYVSQIIKNYTNIEKTPQSEAAIAELNQGGNVYEKLAKSIAPEIYGHEDVKKALLLLLVGGVTKELGDGMRIRGDINICLTGDPGVAKSQLLKYISKVAPRGVYTTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYGRYNPKVAPIHNINLPAALLSRFDILFLILDTPSRETDEHLAQHVTYVHMHNEQPKMDFEPLDPNMIRHYISSARQYRPVVPKDVCDYVTGAYVQLRQNQKRDEANERQFAHTTPRTLLAILRMGQALARLRFSNRVEIGDVDEALRLMSVSKSSLYDDLDPSSHDTTITSKIYKIIRDMLNSIPDVEGNERSLTLRAIRERVLAKGFTEDHLINTIQEYTDLGVLLTTNNGQTIMFLDPDLHMEN
What is the function of this protein?
Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.  The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit.  The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity).  Required for the progression of S phase (PubMed:11606526).
What are the official names of this protein?
DNA replication licensing factor mcm7, Minichromosome maintenance protein 7.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
Protein: ORF5_BOTVX
Sequence: MSDFNDELVIRCGDTVYSPIVCSVLHPTISAKDEIVMHVDVIHSPPKYRGFANSTRHIMPWRMEHNHKTMSSGLHCTDVLAVEKEALPGAIATFFSSLKTPINITFPDKVHVTREPLKPNDNAHIDEA
What are the official names of this protein?
Uncharacterized ORF5 protein.
Protein: ASGR1_MOUSE
Sequence: MTKDYQDFQHLDNDNDHHQLRRGPPPTPRLLQRLCSGSRLLLLSSSLSILLLVVVCVITSQNSQLREDLLALRQNFSNLTVSTEDQVKALSTQGSSVGRKMKLVESKLEKQQKDLTEDHSSLLLHVKQLVSDVRSLSCQMAAFRGNGSERTCCPINWVEYEGSCYWFSSSVRPWTEADKYCQLENAHLVVVTSRDEQNFLQRHMGPLNTWIGLTDQNGPWKWVDGTDYETGFQNWRPEQPDNWYGHGLGGGEDCAHFTTDGRWNDDVCRRPYRWVCETKLDKAN
What is the function of this protein?
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed.  The receptor recognizes terminal galactose and N-acetylgalactosamine units.  After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated.  The receptor then returns to the cell membrane surface.
What are the official names of this protein?
Asialoglycoprotein receptor 1, ASGP-R 1, ASGPR 1, Hepatic lectin 1, HL-1, mHL-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: GMHA_GEOSL
Sequence: MIDDITAQLRAGRQVLEALERELAGRIASFAELLADSLAGGRKLLVMGNGGSAADAQHFAAEIVGRFKLERRGLPAVALTTDTSILTAIGNDYGFDAIFRRQVEALADEGDVVVGISTSGNSRNVQEALLLARERGCRTIGLLGRDGGSIRDIVDLDLTVPSADTPRIQEGHITIIHIVCDLVEKRLFP
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_MYCVP
Sequence: MKHLLTAADLSREDATAILDNADRFREALVGREVKKLPTLRGRTIITMFYENSTRTRVSFEVAGKWMSADVINVSSSGSSVAKGESLRDTALTLRAAGADALIIRHPASGAAQQLAAWTLDEHGGPSIINAGDGTHEHPTQALLDALTIRQRLGSVEGKRVVIVGDVLHSRVARSNVALLHTLGAEVVLVAPPTLLPVGVADWPVTVSQDIDAELPLADAVLMLRVQAERMNGGFFPSSREYSVRYGLSEKRQSRLAEHAVVLHPGPMLRGMEIAYSVADSSQSAVLQQVSNGVHVRMAVLFHLLVGSEQEAISA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PA2BB_TRIST
Sequence: SLLEFGRMIKEETGKNPLSSYISYGCYCGWGGQGEPKDDTDRCCFVHDCCYGKLWGCSPKTDIYFYFRKNGAIVCGRGTWCEKQICECDKAAAICFRENLATYKEEYHSYGKSGCTEKSPKC
What is the function of this protein?
Snake venom phospholipase A2 that induces fast and sustaining local edema a few hours after injection (5-10 ug) in the hind paw, and prolongs the coagulation time of human plasma.  Exhibits moderate hydrolytic activities and prefers the zwitterionic micelles (dPPC with Triton X-100) to the anionic micelles (dPPC with deoxycholate).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Basic phospholipase A2 Ts-G6D49, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ADDB_STAHJ
Sequence: MELNAYIGRAGTGKSHHMIDNIKQQMKEDPLGDPIVLIAPTQSTFQLEQAFVNDKELNGSLRTEVLHFERLSYRVFQEVGGLTEERLTQAATEMMIYDLVQQHKSELKLYQSQVNYYGFSEKLSEQIQDFKKYSVTPEHLHTFLQDNDLKTRTRHKLEDISLIYQYFEERINGEFITSEDSLNHFIDILSQSEWIKRAEVYIDGFHNFSTLEYQIIKALVQSAKKVTVLLTTDGNEDPFSLFRKPSEVLTHLKEIAKDLNIELQQQFFKQQYRFNNKDLIQLEQQFDALQINPIAYDGSINILESSSIREEVNEVARQIIKDTRDKQYRYQDIAILYRDEAYAYLFDSVLPQYDIPFNIDTKRSMTHHPIMEMVRSLLEVIQTNWNISPMMRLIKTNILTNHFKDSAYLIDLLENFVVERGVYGKRWLDEKLFSIDNFTKMGRKEHKLTTEEREDFEQVVHLKNDIIDKILTFEKAMNEAENVRGFATAFYETMEAFDLPKYLMTHRDQLDVDGRHEEAEEIDQIWNGLIQILDDLVTVFDNEEMTLKRFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKKHIYMVGMNDGAMPQPVSSSSLITDEEKKVFEQQAQVELSPTSDILQMDEAFVCYIAMTRGSEQVTFSYSLMGAQGEDKEKSPFIDQIQGLFNGLEVMNIHYQHNAQPLSLMEHPHQTKVVLFESLKAWLEAEMVADVWVDAYQVMRDNDKLNNGLEYLLTALTYDNETVKLDEPLAASLYGSTINASVSRFEGYNDCPFKHYANHGLRLNERTKYKLENFDLGNIFHTALKYISDKVDGDFKNLDNKKIHALTVEALENVLPQVQFNLMDSNAYYRYVSKRIGVIVESTLKALRYQNKNTKFKPQRFEAGFRKTPNNSEELIAQPLITKQGIPVNIRGQIDRIDAYTKDDKSYINIIDYKSSNPSAKLDLKKVYYGKQMQMMTYMDIALQNAQRLGLSNEIKPGGLLYFHVHDERLSFKDWGELEDDALTQDKLEQAFLKEYKLRGLVNSDMDVVDALDIRLEEIGKSDIVPVSLKKDGSIGSRGSSVADETTIHKFIKHNKDNFIKTATNIMEGHTEVAPLKFDDQLPCQFCNFQSVCHVDTIIDSKHYRHVEETIDPIKAIQDVELESGDHNE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: PHSB_SALTY
Sequence: MNHLTNQYVMLHDEKRCIGCQACTVACKVLNDVPEGFSRVQVQIRAPEQASNALTHFQFVRVSCQHCENAPCVSVCPTGASYRDENGIVQVDKSRCIGCDYCVAACPFHVRYLNPQTGVADKCNFCADTRLAAGQSPACVSVCPTDALKFGRLDESEIQRWVGQKEVYRQQEARSGAVSLYRRKEVHQEGKA
What is the function of this protein?
Component of the PhsABC thiosulfate reductase that catalyzes the reduction of thiosulfate to sulfite and hydrogen sulfide, with menaquinol as the sole electron donor.  Proton motive force (PMF) is required to drive transmembrane electron transfer within the reductase.  The PhsB subunit transfers electrons between PhsC and PhsA.
What are the official names of this protein?
Thiosulfate reductase electron transfer subunit PhsB, Thiosulfate reductase subunit beta.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side.
Protein: HEMH_HELP2
Sequence: MNLINEKLNNLENNAAKSPKEAVILLNMGGPNSLYEVGVFLKNMFDDPFILTIKNNFMRKMVGKMIINSRIEKSKKIYEKLGGKSPLTPITFALTERLNELDPSRFYTYAMRYTPPYASMVLQDLALKEVESLVFFSMYPQYSSTTTLSSFNDAFNALKSLETFRPKVRVIERFYADKKLNEIILNTILSTLNNRKSQDFVLIFSVHGLPKSIVDAGDTYQQECEHHVSLLKELMQQKNIPFKEVLLSYQSKLGPMKWLEPSTEELIEKHRKSNIIIYPLAFTIDNSETIYELDMQYRLMAERLAIKEYLVCPCLNDSIEFAKFIIERVKNLKE
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCRY_METTM
Sequence: MPMYEDRIDLYGADGKLLEEDVPLEAISPLKNPTIANLVSDVKRSVAVNLAGIEGSLRKAALGGKSNFIPGREVELPIVENAEAIAEKVKKLVQTSEDDDTNIRLINNGQQILVQVPTTRMGVAADYTVSALVTGAAVVQAIIDEFDVDMFDANAVKTAVMGRYPQTVDFTGANLSTLLGPPVLLEGLGYGLRNIMANHVVAITRKNTLNASALSSILEQTAMFETGDAVGAFERMHLLGLAYQGLNANNLLFDLVKENGKGTVGTVIASLVERAVEDGVVKVAREMNSGYKVYEPADWALWNAYAATGLLAATIVNVGAARAAQGVASTVLYYNDILEYETGLPGVDFGRAMGTAVGFSFFSHSIYGGGGPGIFHGNHVVTRHSKGFALPCVAAAMCLDAGTQMFSVEKTSGLIGSVYSEIDYFREPIVNVAKGAAEVKDQL
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase II subunit beta, MCR II beta, Coenzyme-B sulfoethylthiotransferase beta.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase beta subunit family.
Protein: DSBB2_PSEPK
Sequence: MLPARLRTFFLPACLVALAVLVASFRLENTVGLMPCPLCLSQRLLLGGYALLCFAAVLQAPGTRGILRYARLALGCSLAGALLAARHVWLQGAEGVNEVCPVPIGRVFEQSWSEAARQLLLGGPDCRSLAWSFLDLTLPEWSLLAFLLLAVLPLSCLLAYRFRTLART
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein (By similarity).
What are the official names of this protein?
Disulfide bond formation protein B 2, Disulfide oxidoreductase 2.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RF3_SHESR
Sequence: MSDNKVEVDKRRTFAIISHPDAGKTTITEKVLLFGNALQKAGTVKGKKSGQHAKSDWMEMEKDRGISITTSVMQFPYGGALVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEDRTIKLMEVTRLRDTPIVTFMNKLDRDIRDPIELMDEVEDVLNIACAPITWPIGSGKEFKGVYHILRDEVVLYQSGMGHTIQERRVIEGIDNPELDKAIGSYAADLRDEMELVRGASNEFDHQAFLKGELTPVFFGTALGNFGVDHILDGIVEWAPKPLPRESDARMIMPDEEKFTGFVFKIQANMDPKHRDRVAFMRVCSGRYEQGMKMHHVRIGKDVNVSDALTFMAGDRERAEVAYPGDIIGLHNHGTIRIGDTFTQGEKFRFTGVPNFAPEMFRRIRLRDPLKQKQLLKGLVQLSEEGAVQVFRPLDTNDLIVGAVGVLQFEVVVGRLKSEYNVEAIYEGISVSTARWVYCKDERKLEEFRRKCSQNLALDGGDNLTYIAPTMVNLNLSMERYPDIEFAKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPQB_STRAW
Sequence: MGAEGGGRRRALRLGAYVGCGAVLLTGCASMPDSGDLRGVESTPRQDAQVRVFAMPPREDAAPAEIVQGFLEALTSDDPQYETAREYLTGDASKQWRPYKSTTVLADGPNPEPERTRNRETGDDFAYTLTGSRLAKVDGQHAYAPDSGDYTGTVHLTLQRKTGQWRIDALPQGVVMGKSDFERNYKSVNKYYFASNVPAGTSGQLGTVADPVYVRGKVDPVTAMVTELLKGPTRWLAPVARSSFPTDTGLKKGVTSLAPDDQNKLTVPLNKKADRVGRAQCTKMAAQLLFTLKDLTPTGVDEVELQRSDGSTLCDLGEAEAESIASHGTGKSGEYEYFIDGEQRLVRLSGSSNGKDPDPVPGALGEGAKKLRAAAVSRDEVTAAGVSFDGSSLYVGSLVSGASLGEAVVHSAGTTEKDRLTTPSWDGGGDLWVADRDPAKSRLLLLQKGSGEPLEVRTPRLDGRIDAVRVAADGVRIALIVERDGKTSLQIGRIERETKADERADVSILELHSVTPQLEEVTAMSWAGDSRLVVVGREKGGVQQMRYVQVDGSTPSGSAPASLTGVQQIAASEDERLPLVAYSEDGIVRLSSGAQWQKVMKEGTAPVYPG
What are the official names of this protein?
Lipoprotein LpqB.
What is the protein family that this protein belongs to?
Belongs to the LpqB lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NDK_STRM5
Sequence: MALERTLSIIKPDAVAKNVIGEIYARFEKAGLKVVAAKYKQLSRREAEGFYAVHRERPFFNALVEFMISGPVMIQALEGENAVLAHRDLLGATNPKEAAPGTIRADFAESIDANAAHGSDSVENAAIEIAYFFAATEVVSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_RICTY
Sequence: MSKDDLIQFTGTVLELLPNATFRVKLENDHVIIAHTSGRMRKNRIRILLGDKVTVEMTPYDLTKGRVIHRH
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTHR_HUMAN
Sequence: MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICSLAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVHMFLLARSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRYW
What is the function of this protein?
Receptor for corticotropin (ACTH).  This receptor is mediated by G proteins (G(s)) which activate adenylate cyclase (cAMP).
What are the official names of this protein?
Adrenocorticotropic hormone receptor, ACTH receptor, ACTH-R, Adrenocorticotropin receptor, Melanocortin receptor 2, MC2-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TATA_SALTI
Sequence: MGGISIWQLLIVAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDDAKQDKTSQDADFTAKSIADKQGEAKKEDAKSQDKEQV
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PUR9_PSEF5
Sequence: MTDQTTRLPIRRALISVSDKTGILEFAKELEALGVEILSTGGTFKLLQDNGVSAVEVADYTGFAEMMDGRVKTLHPKIHGGILGRRGIDDAIMNEHGIKPIDLVAVNLYPFEATINKPGCDLPTAIENIDIGGPTMVRSAAKNHKDVAIVVNASDYAGVLESLKAGGLTYAQRFDLMLKAFEHTAAYDGMIANYMGTVNQAAETLSTSGRSEFPRTFNSQFIKAQEMRYGENPHQSAAFYVEAKPAEVGIATATQLQGKELSYNNVADTDAALECVKSFVKPACVIVKHANPCGVAVSPDAEGGIRQAYELAYATDTESAFGGIIAFNRELDAATAKAIVERQFVEVIIAPSVSEEARAIVAAKANVRLLACGQWSAERAAAWDYKRVNGGLLVQSRDIGMISADDLKVVTKRAPTEQEINDLIFAWKVAKYVKSNAIVYAKNRQTIGVGAGQMSRVNSARIAAIKAEHAGLQVAGSVMASDAFFPFRDGLDNAAKVGITAVIQPGGSMRDNEVIAAADEAGIAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: FOLD_EHRCJ
Sequence: MEANIINGKAIAEDITGTLATCINDLKLQYSLVPCLIVVLVGDDPASHLYVRNKQRKAEMLGLRSETILLPSTTSESSLIDKIHELNNDDNVHGILVQLPVPKHIDKNLIINTIDPRKDVDGFHNDNVGRLFTGQKRNCLIPCTPRGCLYLIKTVTHNLSGSDAVVIGRSNIVGKPMACLLLGENCTVTTVHSATRNLSDYCSKADILVAAVGIPNFVKSSWIKPGAIVIDVGINSVEEDGVKKFVGDVNFAEAKNVASAITPVPGGVGPMTIAFLMVNTVMAACNQSGIENFVEKYLDL
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.