PharMolix/UniProtQA huggingface dataset:
Protein: RNH2A_DICDI
Sequence: MDNKIIYLTELDSSVDKSEPFVMGIDEAGRGPVMGPMVYGCCYAPISKSTTLKSMKFNDSKKLTEQQRDQLFDKMGESNKILAYETDVITAEILSEKMLYKKPISLNVISHESAIGLIRSVLKKGVNVQELYLDTVGPPDKYQLMLKKLFPEIGKIIVSKKADSLYPIVSAASIAAKVVRDFEITNKNFDYLNIYDQDEQLSTDFGSGYPSDPLSKKWLVKNRDKVFGYPNFIRFSWKTTETAMRGACFGVDWVLENDKLKQHFQENQNDKKRFMFFKENNIENCINDF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.  Participates in DNA replication (By similarity).
What are the official names of this protein?
Ribonuclease H2 subunit A, RNase H2 subunit A.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. Eukaryotic subfamily.
Protein: DEFB5_RAT
Sequence: MRIHYLLFSFLLVLLSPLSVFTQSINNPVSCVTHGGICWGRCPGSFRQIGTCGLGKVRCCKKK
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 5, BD-5, Defensin, beta 5.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCS2_JANSC
Sequence: MAQTFSDEHFTLGIEEEYLLVDAETYDLAEAPDALMAACADKLSSKVSPEFLQCQIEVGTGVCASIADARADLRNLRATVAECAGRFGLAPIAVSCHPFADWKDQSHTDKDRYNQLARDLGGVVERMLICGAHCHVGLPSENDRVDIMRQMTYFLPHLLALSTSSPFWQGRDTGLASYRLTVFDNLPRTGLPPSFASFDEFQRTVDLLVDMEMIEDSSKIWWDLRPSAAFPTLETRICDVSPRLEDQLSLSALIQCLTRMLMRLRGSNQRWRVYDRFLINENRWRAQRYGVSDGLIDFGRGAVVPLPELVDELIELTEQDAEALGCVDEVQRLRDLAVETSSDRQRKIYKGTRAAGGSHQAAMRSVVEHLLEDFHVDL
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: LAYN_HUMAN
Sequence: MRPGTALQAVLLAVLLVGLRAATGRLLSASDLDLRGGQPVCRGGTQRPCYKVIYFHDTSRRLNFEEAKEACRRDGGQLVSIESEDEQKLIEKFIENLLPSDGDFWIGLRRREEKQSNSTACQDLYAWTDGSISQFRNWYVDEPSCGSEVCVVMYHQPSAPAGIGGPYMFQWNDDRCNMKNNFICKYSDEKPAVPSREAEGEETELTTPVLPEETQEEDAKKTFKESREAALNLAYILIPSIPLLLLLVVTTVVCWVWICRKRKREQPDPSTKKQHTIWPSPHQGNSPDLEVYNVIRKQSEADLAETRPDLKNISFRVCSGEATPDDMSCDYDNMAVNPSESGFVTLVSVESGFVTNDIYEFSPDQMGRSKESGWVENEIYGY
What is the function of this protein?
Receptor for hyaluronate.
What are the official names of this protein?
Layilin.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Note=Colocalizes with TLN1 at the membrane ruffles.
Protein: DNLJ_BARBK
Sequence: MDKDAKNLTALEAERELEWLAKEIARHDVLYNNHDQPEISDARYDALRRRNIEIETLFPELVRADSPSYKVGAPISERFEKSVHAQAMLSLDNAFSSEDVHEFVERVRRFLRLPVTKTLEMTAEPKIDGLSLSLRYEKGKLVCAATRGDGYVGENVTVNARTLSDIPQVLQGDFPDILEVRGEVYMRHSDFQDLNVDQQEKGKLVFANPRNAAAGSLRQLDTRMTARRKLKFFAYGWGEVSEMPAKSQMEMVKKLKEYGFVINPLTKVFKAVEDLISYYHFIEEGRQHLDYDIDGVVYKVNDLLLQTRLGNVSRSPRWAIAHKFPAEKAMALLENIDIQIGRTGALTPVARLAPITVGGVVVTNASLHNEDYIKGLGSKSESIREGRDIRIGDTVIVQRAGDVIPQIIDVIIEKRPKGASPFVFPSLCPACGSHAVREVGEAVRRCTGGLICPAQAIERIRHFVSRNAFDIEGLGEKQVEFFFHAQDETLRIHSPADIFTLQKRQEKSLTRLENMEGFGTLSVRKLYDAINARRKIPLSRFLFALGIRHVGEVNARRLARAYQNYNAFETVAMTALMPCNKEDKGNEEWLELTSIEGIGVRVGKAIIDFYQETHNRDVLSSLLQEVTPLPEEAAVADYSPVAGKTIVFTGTLVHMSRDEVKALAERLGAKASSSISKKTDLLVAGIGAGSKLTKAKELGIEIMDEESWLQLINEHHI
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: END4_STAAS
Sequence: MLLGSHVSMSGKKMLEGSAIEAYEYGETTFMIYTGAPQNTRRKSIEDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIGAKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEELARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSKNDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLEIEMLKQQQFDPELKNKVMQQ
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: TMPS9_HUMAN
Sequence: MEPTVADVHLVPRTTKEVPALDAACCRAASIGVVATSLVVLTLGVLLAFLSTQGFHVDHTAELRGIRWTSSLRRETSDYHRTLTPTLEALLHFLLRPLQTLSLGLEEELLQRGIRARLREHGISLAAYGTIVSAELTGRHKGPLAERDFKSGRCPGNSFSCGNSQCVTKVNPECDDQEDCSDGSDEAHCECGLQPAWRMAGRIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLYGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTKASMPLAPTMAPAPAAPSTAWPTSPESPVVSTPTKSMQALSTVPLDWVTVPKLQECGARPAMEKPTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAHCFNHTKVEQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILEIMSSQPLPMSPPSTTRMLATTSPRTTAGLTVPGATPSRPTPGAASRVTGQPANSTLSAVSTTARGQTPFPDAPEATTHTQLPDCGLAPAALTRIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGTPFLSGAEGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPAPRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTCRRFYPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQE
What is the function of this protein?
Serase-1 and serase-2 are serine proteases that hydrolyze the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC.  In contrast, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Ala-Pro-Ala-AMC are not significantly hydrolyzed.
What are the official names of this protein?
Transmembrane protease serine 9, Polyserase-I, Polyserine protease 1, Polyserase-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: CYNS_PARBD
Sequence: MSNINLATLDISEHPNLPSSSAVLFEAKAKKKLSFEAIASAIGRNEVATAAIFYGQAKASAEDIVKLSEVLGIDHLYLESLLSGFPDRGKSMTFPPKDPLIYRLFEIVQNYGYAYKAVMNEKFGDGIMSAISFSTKVEKETDLDGNNWAVVTWRGKWLPYSRF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: TSYL5_MOUSE
Sequence: MSGRSRGRKSSRAKGRGKGRARARVRAAAEDAWHDEKPPQSPRLGEDSAAAQVQAGAAQGGAEPAELREEAACRLPLDCGLALRARAADERGLAAPDPDLERARSLAERLTSDTSFVGTVGALAKLRRGSRIGNRRVPGRKAPDTRSATGRGPQATVSGKPKMASAGLCAAAPVGEEKKMTEKHAGAGSPATVGSMDTLETVQLKLETMNAQADRAYLRLSRKFGQLRLHHLERRNLLIQSIPGFWGQAFQNHPQLSAFLNTKDKEVLSYLNRLEVEELGLARLGYKIKFYFGRNPYFQNKVLIKEYGCGPSGQVVSRSAPIQWLPGHDLQSLSKENPENNGSFFGWFSNHSSIESDKIVEIINEDLWPNPLQYYLISEEARGEKGKEERPGPAKLSPAPAVRQPN
What is the function of this protein?
Involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway.  Involved in regulation of p53/TP53.  Suppresses p53/TP53 protein levels and promotes its ubiquitination; the function is dependent on USP7 and independent on MDM2.  Proposed to displace p53/TP53 from interaction with USP7 (By similarity).
What are the official names of this protein?
Testis-specific Y-encoded-like protein 5, TSPY-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
Protein: BUB1_SCHPO
Sequence: MSDWRLTENVLDQNIPETKPRESKTRLEEIQRLALFQEELDIIEELDDPVDVWYRCIEWLLETRFLGMETVNKMLDDAIQYLERCRFALNDVRHLLIQLAKIKQSYETPDELQQAAKQFYQLASKGIGLELALFYEEYGSLLIRMQRWKEASEVFHAAVSREARPLVRLLRNAAEFSRAYDLHNAHPSIHDAPYSSPFPPPRIVLGSKPVSSSTLPSKPKSFQVFSDASSSRDSQNASDLPQAKSLESEANTPNLPLLYDKSSGKRVEYSAFNFLALYENGEERSMEECRAQRYLSSIQPNTAASFPKVVPKNEISVHHDSSSSNVSPIYKNPVAEQSDTPTRSLPKNYAYVAKSTSPELKVFDTVMPVALSPKPAQKPPSPTIHTKAALADILDIFNQPLRSESLEKSSKSPISAQSSYLGTPLKNDENSSNSGATSLTGRSQEEHLDFIPSLTPSKNYPSKIYSPNKNLDFSHTASKAETYKNSNELENVKREQPFSELLPSTLQEETATGTTSTTFANAKRRPEDSNISPTNPKKLHTLPRSPQYSTVDSNSVLSPAMPKGYMFVNENQSMKHESSVSNPVATIPHENGKHDFGQLSPIEHKPFFPKNDDELPGPSGYLTMPYEEAMASLSNLPTLINPLDQSLRDLLFQVLRPSLLRDKDYHEHETSFALVEHIESFVSKIKPKAGGPGRRRSSNRHSLDGPEFHLFYPPNTNLSVISKLGQGAFAPVYLVKSKIETENGDVSQGGAENNESKLFALKIETPPSCFEFYLTRQAMTRLKGLRETNSILPVHQLHMFHDTSHLLMDYRPQGSILDLVNSMHNSTFSSSGMDEILVVFFSIEFLRIIEALHTHKIIHGDLKADNALLRLETVADSEWSPIYSPEGLYGWSFKGIYLIDFGRGIDLSLFEEKVKFIADWDTDLQDCIEMREGRPWTYQIDYHGLAAIIYTMLFGQYIETRIEVINGQRRQVLTQRMKRYWNQDLWHRLFDLLLNPTLHVSEENLPMTEELSKIRIEMEEWLVNHSTGGSGLKGLLKSIEKRKI
What is the function of this protein?
Involved in cell cycle checkpoint enforcement.  Acts to stabilize the spindle during mitosis.  Required for the correct localization of bub3 and mad3 to the kinetochore.  Appears to have a role in chromosome segregation.  Catalyzes the phosphorylation of bub3.
What are the official names of this protein?
Checkpoint serine/threonine-protein kinase bub1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. BUB1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Chromosome, centromere. Note=Associates with kinetochores and centromeres during the early stages of mitosis.
Protein: GSA_TROWT
Sequence: MRTNFEWFEEAKRFIPGGVNSPVRAYAAVGGTPRFLAKAQGAYVTDIEGREYVDLVSSWGPLILGHAHPKVIDAVINTAHRGMSYGAPTTLEVELAELVCNRICNAQGIKPVERLRLVSTGTESCMTAIRLARCFTGRDLIVKFSGHYHGHADPFLIDAGSGLVGHPSSGGVPESVAKNTLVVPYNDLAVLEYLFEAYPNQIACIITEACPANMGVIPPDPGFNARVADLGHSHGALIIFDEVITGFRVGSGGFWALETSLASQQPTQAVSEGSVSDSAYSAYVPDLFTFAKVLGGGLPIGAIGGRAEIMDLLSPSGPVYQAGTLSGNPLATAAGLATLRLADSNIYEHMNRVARALINEIQSAFHDAGVPCTVQSAGNLFGISFSAIAPRDFTQATSQEHWRYSNFFHSMLNSGVLLPPSVYEAWFVSAAFDDRAIERVVNALPDAVRAAGSAPARPKGFEPPTF
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_GLOVI
Sequence: MPTIAQLIRRERGIAQRKTKSPALKACPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGFEVTAYIPGVGHNLQEHSVVMIRGGRVKDLPGVRYHIIRGTLDTAGVKNRMQSRSKYGTKRPKPGQAAAPAGKKR
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RBM26_MOUSE
Sequence: MVSKMIIENFEALKSWLSKTLEPICDADPSALAKYVLALVKKDKSEKELKALCIDQLDVFLQKETQIFVEKLFDAVNTKSYLPPPEQPSSGSLKVDFLQHQEKDIKKEELTKEEEREKKFSRRLNHSPPQSSSRYRDNRSRDERKKDDRSRKRDYDRNPPRRDSYRDRYNRRRGRSRSYSRSRSRSWSKERLRDRDRDRSRTRSRSRTRSRERDLVKPKYDLDRTDPLENNYTPVSSVSNISSGHYPVPTLSSTITVIAPTHHGNNTTESWSEFHEDQVDHNSYVRPPMPKKRCRDYDEKGFCMRGDMCPFDHGSDPVVVEDVNLPGMLPFPAQPPVVEGPPPPGLPPPPPILTPPPVNLRPPVPPPGPLPPSLPPVTGPPPPLPPLQPSGMDAPPNSATSSVPTVVTTGIHHQPPPAPPSLFTAVFVLPDTYDTDGYNPEAPSITNTSRPMYRHRVHAQRPNLIGLTSGDMDLPPREKPPNKSSMRIVVDSESRKRTIGSGEPGVSTKKTWFDKPNFNRTNSPGFQKKVQFGNENTKLELRKVPPELNNISKLNEHFSRFGTLVNLQVAYNGDPEGALIQFATYEEAKKAISSTEAVLNNRFIKVYWHREGTTQQLQTTSPKVIQPLVQQPILPVVKQSVKERLGPVPSATTEPAEAQSATSELPQNVTKLSVKDRLGFVSKPSVSATEKVLSTSTGLTKTVYNPAALKAAQKTLSVSTPAVDNNEAQKKKQEALKLQQDVRKRKQEILEKHIETQKMLISKLEKNKTMKSEDKAEIMKTLEILTKNITKLKDEVKSTSPGRCLPKSIKTKTQMQKELLDTELDLYKKMQAGEEVTELRRKYTELQLEAAKRGILSSGRGRGIHTRGRGTAHGRGRGRGRGRGVPGHAVVDHRPRALEISAFTESDREDLLPHFAQYGEIEDCQIDDASLHAIITFKTRAEAEAAAIHGARFKGQDLKLAWNKPIANMSAVDTEEAEPDEEEFQEESLVDDSLLQDDDEEEEDNESRSWRR
What are the official names of this protein?
RNA-binding protein 26, Protein expressed in male leptotene and zygotene spermatocytes 393, MLZ-393, RNA-binding motif protein 26.
Protein: RL4A_XENLA
Sequence: MAVSMACARPLISVYSEKGESSGKNVTMPAVFRAPIRPDIVNFVHTNLRKNNRQPYAVSKLAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTWRRWHRRVNTTQKRYAVCSALAASALPALIMSKGHRIEEIPEVPLVVEDKVESYKKTKEAVLLLKKLKAWNDIKKVYASQRMRAGKGKMRNRRRIQRRGPCVIYNENNGLVKAFRNIPGITLLNVSKLNLLRLAPGGHVGRFCIWTESAFRKLDDLYGTWRKSAKLKADYNLPMHKMTNTDLTRILKSQEIQRALRAPNKKVKRRELKKNPLKNLRIMMRLNPYAKTARRHAILQQLENIKAKEKKPDDGKPKAKKPLDAKTKMIKLAKAKKRQAREAAKAAETK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L4-A, L1A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT1B1_PANTR
Sequence: MARGKAKEEGSWKKFIWNSEKKEFLGRTGGSWFKILLFYVIFYGCLAGIFIGTIQVMLLTISEFKPTYQDRVAPPGLTQIPQIQKTEISFRPNDPKSYEAYVLNIVRFLEKYKDSAQRDDMIFEDCGDVPSEPKERGDFNHERGERKVCRFKLEWLGNCSGLNDETYGYKEGKPCIIIKLNRVLGFKPKPPKNESLETYPVMKYNPNVLPVQCTGKRDEDKDKIGNVEYFGLGNSPGFPLQYYPYYGKLLQPKYLQPLLAVQFTNLTMDTEIRIECKAYGENIGYSEKDRFQGRFDVKIEVKS
What is the function of this protein?
Involved in cell adhesion and establishing epithelial cell polarity.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-1, Sodium/potassium-dependent ATPase subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein. Cell membrane, sarcolemma. Note=Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes. Localizes in long striations at the level of Z and M lines.
Protein: PSY_ONCHC
Sequence: MAASQLCFVGFLEGIRGGDRLWNAKNDCRFSQRKKMRWSFYCLFTNFNYACVSQEPEKDLKFPIYSSLVVNPVGEVAISSEQKVYDVVLKQAALVEQQLRNRTVLEEKTGTTFLLNEAYDRCGQICEEYAKTFYLGTLLMTPERRRAIWAIYVWCRRTDELVDGPNASHITPSALDRWEARLEDLFAGRPYDMLDASLSDTVVNFPVDIQPFKDMIEGMRMDLKKSRYKNFDELYLYCYYVAGTVGLMSVPVMGIDPESDATTESVYNAALSLGIANQLTNILRDVGEDTRRGRVYLPQDELAEAGLSDEDIFNGKVTDRWRNFMKNQIKRARTFFQEAEKGIAELNQASRWPVLASLLLYRQILDEIEANDYNNFTKRAYVSKAKKLMAVPVAYGRSLIRPSMKKPSLVKP
What is the function of this protein?
Catalyzes the reaction from prephytoene diphosphate to phytoene.
What are the official names of this protein?
Phytoene synthase, chloroplastic, OgPSY.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LON_CITBB
Sequence: MTENITINMPEIVPLYPLREIIAFPYMVFTIFLKQEDMPPFEEAVLFNNLVALVKLREEPTGELFPALHEIGTLCKVMQINKLAGGGAKVVLEGVIRVRLLAIVQQTPVALSRLEPVREFAEKSMVSEALVGSLNALLKIALSYGRPLPDDVMKMIDFIDNPARLSDLVALYLNLPIDELQKLLETVDPLERLKKVYMHLTNEVQRLQIKGEVQAEVTKKVGKSQKEFLLREQMKQIQEELGEEDSRLGEANELRSKVESAHMPEDVRRIAEKEMRRLERINPASPEYTVSRTYLDYLTTIPWQVSTPDNRDINQAETILNEDHYDLKKVKERILEYLAVRSLKDKMKGPILCFVGPPGVGKTSLGKSIARTLGRKFIRISLGGMRDEAEIRGHRRTYIGALPGRIIQEINRAGSNNPVFMLDEVDKIGADFRGDPASALLEVLDPEQNFSFTDHYLDVPFDLTNVMFITTANQLDPIPAPLKDRMEVITLSGYTDEEKLNIAKSYLVAREVEENGLASMAPQFTDEAIYRVTHDYTREAGVRNLQRNIASICRKIAKEVAQGKKARPIVNPETVSELLGAPKFFDEVASEKDRVGVATGLAWTESGGDIIFVEATKMKGKEDLILTGSLGEVMKESVRAALSFVKANCAELGIDKKMFDETTLHIHVPAGSIPKDGPSAGITMATAIVSLFSGRAARRDVAMTGEMSLTGRVLAIGGLKEKVLAARRAGVKKVLAPAKNKKDLEDIPENVKNELEFFFVEDIREVFVQALNPTSPAPTAATSARTPAGAPPPQ
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_SHESM
Sequence: MTSLTLALDAMGGDHGPHVTVPAALRALKSHSSLKIILVGDKTEIDVYLRQAEQPLLSRIEVIHTDEVVSMSDRPVHALRTRKNSSMRLSIELVRDGRAAACVSAGNTGALMAMAKVLLKTLPGVDRPALVSCLPSVTQKPVYLLDLGANISCDSETLFQFAVMGSVLCEAVDKKSRPKVALLNVGTEEIKGNDQVQQAAQILQNTDQINYTGFIEGDEIYSGNVDVIVCDGFVGNITLKTSEGIAKLLVHQLKRGLTQGFFVRFLAKLIAPRIQAVLSQMNPDHYNGASLIGLRGIVVKSHGNADETAYLQAINLAVTEAQRRLPEMIKDRLESILLDINN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: CH60_BLOPB
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPVITKDGVSVAREIELEDKFENMGAQMVKEVASKANDSAGDGTTTATVLAQSIVNEGLKAVAAGMNPMDLKRGIDKAVVAAVEELKKLSVPCSDPKAIAQVGTISANSDETVGKLIAQAMDKVGKEGVITVEEGSGLQDELDVVEGMQFDRGYLSPYFVNKPESGTVELEHPFILLADKKISNIREMLPILESVAKAGKPLLIIAEDVEGEALATLVVNNMRGIVKVTAVKAPGFGDRRKAMLQDIAVLTAGTVISEEIGLELEKATLEDMGQAKRVVITKDATTIIDGVGNKSAINSRVAQINQQRDEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVANAIRNLCGDNEDQNVGIKVARRAMEAPLRQIMANAGEEPSVIANNVRSGEGNTGYNAATEKYGNMIELGILDPTKVTRSALQYAASIAGLMITTECMVTELPKEDKPDLGNAGAGGNMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_CANAL
Sequence: MSANIDDVPIEVSKVFDTILVLDFGSQYSHLITRRLREFNVYAEMLPCTQKIAELSWKPKGIILSGGPYSVYAEDAPHVDHDIFKLGVPILGICYGMQELAWINGKGVARGDKREYGPATLNVEDPECALFKGVDHSQVWMSHGDKLHALPTGFKVVATSDNSPFCGISNESEHIYGIQFHPEVTHTVQGKKLLKNFAVDICQAKTNWSMENFIDTEIARIKKLVGPTAEVIGAVSGGVDSTVGAKIMKEAIGDRFHAIYVDNGVMRKNETESVKKTLDEGLGINLTVVDAGDLFLGRLKGVTDPEKKRKIIGNTFIHVFEEEAAKIKPRDGSEIEYLLQGTLYPDVIESISFKGPSQTIKTHHNVGGLLEDMKLKLIEPLRELFKDEVRHLGELLGVPEDLVWRHPFPGPGLAIRVLGEVTKEQVKIAREADAIFIEEIKKAGLYRQISQAFAALLPVKSVGVMGDQRTYEQVIALRAIETLDFMTADWFIFEAAFLKKVASRIVNEVDGVARVTYDITSKPPATVEWE
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_SALPK
Sequence: MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIARLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVLVVLIGYGIIGFVDDYHKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQLVVPFFKDVMPQLGLFYILLSYFVIVGTGNAVNLTDGLDGLAIMPTVFVAAGFALVAWATGNMNFANYLHIPYLRYAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSD2_TOXGG
Sequence: MAKVMRLIIFVCVALVAISVPAASSVQSQQERIRPGFRQQLPSSIRPFSAFRRRGQEASDSVVYLNIVYLRLVGTRQCATGELTVVVHGKALNNATLGDVQTSLTRTFASSLKEPSSTLAIRRWSWKDPLFLMLTLNRRAVRTGTGLPRSTPLYQVAKQRLFVFVRKPTPTSSCRRAALDPRPLYGVPKVGVQDKYTLHVSMDVLGMSLREPLEHQEEEPGPASVSTYAAAQAILDGASSFGIGAFGSAKPNLKQISMYASGAELEKQVYTPTTSQLALFLPSKTFFGVEVTSVSDGTFRIPVSASRLVPFSAMSYMCTGSQTHKLTQTGMNVLEKRVHGKENPPSEGAEVLLNLLAARKPVNGVFEQDPTVVLLQLWRTPEGSESWQETPLMWEFPDTLEAIEDAGEYRSGILSSIAANTRIIGKMAGWLASRSFSRRFIRTLIRLNNIDLEEAFSMSDKDRRHSAADFRSVQEFFTRPINYHVYRDMDPRASIMAPADSLIQNIYTIRPDFKGEISHPIIPQVKSTSFNLREFLYGARQVPPLQLQSPSNRLFVSILYLAPSDYHRVHSPADWRVTSQTYIPGCTPSVSRRNLEAGDLLHRYERTALIGHWDPEKNGQQLFFSVTMVAAMFVGGLRLSWEEEPLGASMRLGRCTRYTESYEKQVDVELCASQEIGAFRFGSTVVMIFEAPEDFDMTSVGQCSHVAAGQPAGYLGQGRERPLQERCNAFRGNFESPFHFWKHLQKTSSVDDILKQNTLAPRAWRQEPGRVWAEVLRATERGLLYGFALSHYLLKRWATENGNLGELVLGQPEVLRQNINGSDSVIREGFRCFAAKDKKQIRLQMSGRQSQVSLTATVTPDEQFLFQHPFYGCVGDEKLGKLVRGIDATWILLPERAVLLTLKVSTGSKQEDGRVLRVATTKIEVQTEPCQGGWEESRVGTTSTTCAIRTVEKREESISEGVLTNGDL
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).  Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.  Can act on liposomal and host cell PtdSer.
What are the official names of this protein?
Phosphatidylserine decarboxylase 2 proenzyme, Phosphatidylserine decarboxylase 1, parasitophorous vacuolar.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family.
What are the subcellular locations of this protein?
Parasitophorous vacuole. Cytoplasmic vesicle, secretory vesicle. Note=The protein is stored in dense granules in the parasite and secreted into the parasitophorous vacuole via these granules after host infection.
Protein: LIPA1_BRADU
Sequence: MVVIVDTISNPLRPRHPEKVNRPDSASPPKPDWIRVRAPNTRGYADTRNIVRANGLHTVCEEAGCPNIGECWDKKHATFMIMGDTCTRACAFCNVKTGLPNALDADEPQNVAEAVAKLGLAHVVITSVDRDDLADGGAEHFAQTIRAIRAACPSTTIEILTPDFLRKEGALEVVVAARPDVFNHNLETVPSRYLTVRPGARYFHSIRLLQRVKELDASIFTKSGIMVGLGEERHEVQQVMDDLRSADVDFLTIGQYLQPTRKHHAVMRYVPPDEFSSYEKVAYTKGFLMVSASPLTRSSHHAGEDFARLKAARAAHAR
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 1, Lip-syn 1, LS 1, Lipoate synthase 1, Lipoic acid synthase 1, Sulfur insertion protein LipA 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.