PharMolix/UniProtQA huggingface dataset:
Protein: MUKF_ECOLI
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALRDEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF, Protein KicB.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: COBS_METBU
Sequence: MSGFLLALRTTFGFLSTIPVGMSMEGLDELVKRSYLQTFAGIVLGSMIGIFAYLTESFLPSTISAVLIMVFIYYITGLNHLDGLGDFGDGATAHGSLEKKVNALKDMSLGIGGVSYTVLALIALYASISSLQAEVLFFSDNAALIIAISLLIAEIGAKQAMLTVAAFGKPIHEGLGSMIINNTTFPRYAVSFVLGALVCVLAFGTLGIIGYISAIVTAFVILNISIRHFKGINGDCIGTSNEIARIIVLMVLTVAITAVNNGYGGLFWTPL
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGK_SHESR
Sequence: MAIINMSDLDLQGKRVLIREDLNVPVSNGVVTSDARLRASLPTIELALAKGAAVMVMSHLGRPTEGEYNSEFSMQPVVDYLAKALSCTVRLATDYLDGVEVAVGEVVVFENVRFNKGEKKNDEALSKKMAALCDVYVMDAFGTAHRAEASTNGVGLHAPIACAGPLLAQELEALGKALDNPARPLVAIVGGSKVSTKLTVLESLSGIVDQLVVGGGIANTFIAAAGHNVGKSLYEADLIDEAKRLVANAQSRGGDIPVPTDVVVAGEFSPTAAATLKAVNEVGDSDMIFDIGPDSAEALAKIIESAGTIVWNGPVGVFEFDQFGEGTKRIAQAIADSKAFSIAGGGDTLAAVDKYDIADKVSYISTGGGAFLEFLEGKELPAVAMLKQRGA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ACIBS
Sequence: MKTIKVTQTKSSSHRLKNHKLCLQGLGLRRIGHTVEVQDTPSNRGMINKVYYMVSVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ENPL_CHICK
Sequence: MKSAWALALACTLLLAASVTAEEVDVDATVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIKEIREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNMLHVTDTGIGMTKEELIKNLGTIAKSGTSEFLNKMTEMQDDSQSTSELIGQFGVGFYSAFLVADRVIVTSKHNNDTQHIWESDSNEFSVIDDPRGNTLGRGTTITLVLKEEASDYLELDTVKNLVKKYSQFINFPIYVWSSKTETVEEPVEEEEAKEEKEETDDNEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKTFSKEHDDPMAYIHFTAEGEVTFKSILFVPNSAPRGLFDEYGSKKSDFIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIAEEKYNDTFWKEFGTNVKLGVIEDHSNRTRLAKLLRFQSSHHESNLTSLDQYVERMKEKQDKIYFMAGASRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFEESEKSKESREALEKEFEPLLNWMKDKALKDKIEKAVLSQRLTQSPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIKDMLRRVKENEDDKTVSDLAVVLFETATLRSGYMLPDTKEYGDRIERMLRLSLNIDLDAKVEEEPEEPEDAAEEAEQDEEEVDADAEDSETQKESTDVKDEL
What is the function of this protein?
Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity).  Has ATPase activity (By similarity).
What are the official names of this protein?
Endoplasmin, Heat shock 108 kDa protein, HSP 108, HSP108, Heat shock protein 90 kDa beta member 1, Transferrin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Sarcoplasmic reticulum lumen. Melanosome.
Protein: NEP_I80A4
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: E13D_TOBAC
Sequence: MALWYLFNKRSLGAAVLILVGLLMCNIQITGAQSNIGVCYGEIANNLPSEQDVINLYKANGIRKMRIYYPDTNIFKALNGSNIEIILEVPNQDLEALANSSIANGWVQDNIRSHFPYVKFKYISIGNEVSPTNNGQYSQFLLHAMKNVYNALAAAGLQDKIKVSTATYSGLLANTYPPKDSIFREELKSFINPIIEFLARNNLPLLANIYPYFGHIYNTVDVPLSYALFNQQETNSTGYQNLFDALLDSIYFAVEKAGGPNVEIIVSESGWPSEGNSAATIENAQTYYRNLVNHVKGGAGTPKKPGRIIETYLFAMFDENEKQGEITEKHFGLFYPNRAAKYQLNFMYSDS
What is the function of this protein?
Implicated in the defense of plants against pathogens.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase, (1->3)-beta-glucan endohydrolase, (1->3)-beta-glucanase, Beta-1,3-endoglucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
Protein: SYM_HALOH
Sequence: MNVFIGGAWPYANGSLHLGHIASLLPGDILARYFRLKGEKVLYVSGSDCHGTPIALRAKREGESPRIIAERYHQEFKKTFTKLGFSYDNYTKTDNPFHHQVVQSIIKKLFEKGYIYKKQTKQLYCSKCQQFLPDRYVEGICPVCGKVVRGDQCDYCSSLIEPTDLEEKRCKICGSSPVIKNTEHFYLALSEFSDELKRLLDNNRGWRDNAIKLSTRYIEEGLQDRAITRDLNWGVSIPFEGYEEKRIYVWIDAVLGYLSASKEWSRHTGEPWQNFWSEDTKTYYVHGKDNIPFHTLILPALLRGAGIKQIPEKIVSSEYLTIEGKKLSTSRNWAVWLPDMLKNYQPDSIRYFLIINGPEKKDSNFSWEEFIHSHNGELLGAYGNFVNRTLVFIEKYYNGLIPDGKLNEKIKEKIETLYHRVGNKIEKTNLKNALEVIFNFVREANKYFDSEEPWITVKEDKGTCKDTIYTCVQIIANLTNLLSPFLPFSSKKVRGFLNIDKPDWKYIEVLPATKLEKVEILFPRINKNLIKEEREKLGVN
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_NEIMF
Sequence: MIQMQTILDVADNSGARRVMCIKVLGGSKRRYASVGDIIKVAVKDAAPRGRVKKGDVYNAVVVRTAKGVRRPDGALIKFDNNAAVLLNNKLEPLGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GATB_PERMH
Sequence: MEFEPVIGLEVHVQMSTNTKCFCSCKIEFGAEPNTNVCPVCLGMPGSLPVLNKKALEYAIKASLALNCEVHELSVFARKNYFYPDLPKGYQISQYDKPLATNGYIDIKVNDKTERIRIHRLHMEEDAGKTIHKGSYSYVDLNRAGTPLMEIVSEPDIRSAVGARLYLEKLRNIMRYIGVSDADMEKGQLRCDVNISLRPKGEEKFGTKVEIKNINSFRFVQKAIEYEIERQARILRKGGEIVQETRLFDEKTGKTFTMRTKEEAHDYRYFPDPDLIPVRITKEYIEEIRKSLPELPDQKAERYVKELKLTEYDAEVLVADKDRALFFEKAVSVYSENPKSIANWIINELLGKLNEEGIEISNSPVRPEHIAELVQLIDKGDISSKIGKEVFEEVFKTGKSPKTIVEEKGLKQVSDEGEIRKIVEEVLNNHPAEVEKYKAGNQKLMGFFVGQVMKATRGKANPKLVNKILQELLK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: Y2048_ERWT9
Sequence: MNKILFTAVEARVVGCLLEKQVTTPDQYPMSLNGVVTACNQKSNREPVMSLTDSEVQNTLDMLVKKHQLTALNTGSRVVKYEQRFCNSTFGQMKLSAAEVAIIANLLLRGAQTPGELRIRCARIHDFADMTEVEQTLERLAQHEHGQLVVRLAREPGKRESRYMHLLSGEVDESSRADGHHPDDHRGDLEGRIAQLEQQVATLQRQIAQLLNNGEVK
What are the official names of this protein?
UPF0502 protein ETA_20480.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: LCPS_BLATR
Sequence: MSILTYLEFHLYYTLPVLAALCWLLKPFHSQQDNLKYKFLMLMAASTASIWDNYIVYHRAWWYCPTCVVAVIGYVPLEEYMFFIIMTLMTVAFSNFVMRWHLHTFFIRPNTSWKQTLLVRLVPVSALLAITYHAWHLTLPNKPSFYGSCILWYACPVLAILWLGAGEYILRRPVAVLLSIVIPSVYLCWADIVAISAGTWHISLRTSTGKMVVPDLPVEECLFFTLINTVLVFATCAIDRAQAILHLYKSSVQNQNPKQAISLFQHVKELAWAFCLPDQMLNNELFDDLTISWDILRKASKSFYTASAVFPSYVRQDLGVLYAFCRATDDLCDDESKSVQERRDQLDLTRQFVRDLFSQKTSAPIVIDWELYQNQLPASCISAFRAFTRLRHVLEVDPVEELLDGYKWDLERRPILDEQDLEAYSACVASSVGEMCTRVILAQDQKENDAWIIDRAREMGLVLQYVNIARDIVTDSETLGRCYLPQQWLRKEETEQIQQGNARSLGDQRLLGLSLKLVGKADAIMVRAKKGIDKLPANCQGGVRAACQVYAAIGSVLKQQKTTYPTRAHLKGSERAKIALLSVYNLYQSEDKPVALRQARKIKSFFVD
What is the function of this protein?
Bifunctional enzyme that catalyzes the reactions from geranylgeranyl diphosphate to phytoene (phytoene synthase) and lycopene to beta-carotene via the intermediate gamma-carotene (lycopene cyclase).
What are the official names of this protein?
Bifunctional lycopene cyclase/phytoene synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: OMP10_RHIME
Sequence: MKPFAILTLLATAAALASCQSQPRELRPMSSAPQATGVEGSWVDPNGIVSTFAGGTFSTRTTDTNQLLASGNYVNVSPTLVEINMTSLVRNTQSKVNCALATPAQLNCTTDSGAQFSLARRG
What are the official names of this protein?
Outer membrane lipoprotein omp10 homolog.
What is the protein family that this protein belongs to?
Belongs to the rhizobiaceae omp10 lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: MNMA_CAMHC
Sequence: MKILVALSGGVDSAVSAKILKDAGYEIEGCYMKLHGRDDYHAKNIEKVQDVGNFLEIKTHILDLCDDFKREVFEPFLQTYKVGKTPNPCALCNRTIKFGKFLDFARSKGCDKIATGHYAKIENNLIKSAVDLSKDQSYFLANIEPRVIPNIVFPLGNMLKKDVKKFAASFPELEKISKSSESNEICFVENTYIDVLREFYKTETPGIVRNLQGEIVGKHNGYMNFTVGKRRGFDVFGAHEPHYVVKIDAKKNEIVVGSKADLDKNEFETQNFNAFLNIDEILKMDEIYVKIRYRSAKIACKIEISLNDNLNNESLTDKNLNFENSDFLNNQDLKAKIILKTPANGVASGQLAVFYDKSDCVIASGFIA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_CAMC1
Sequence: MRNKYIEAFENAQIAGKNIPDFRAGDTLRVATRIHEGDKTRIQNFEGICIARRGSGTGETFIIRKIGANSVGVERIFPIFSDSIEEIKVLRKGRVRRAKLFYLRELRGKAAKIRELRK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: HIS7_AGRFC
Sequence: MAERKGEIIRKTNETSVSVRVDIDGTGKSKISTGVGFFDHMLDQLSRHSLIDMDIEVQGDLHIDDHHTVEDTGIAIGQAIAKALGDRRGITRYASLDLAMDETMTKAAVDISGRPFLVWNVNFSAPKIGTFDTELVREFFQALAQNAGITLHILNHYGANNHHIAETCFKAVARVLRTATEIDPRQAGRVPSTKGMLA
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAD_ECOHS
Sequence: MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURQ_OCEIH
Sequence: MLDKLPTEQRNPKTMDIDTKSIKEILEMMNREDFTVPQTVQKEISFIEEAVHRTIHSFKSNGRLIYIGAGTSGRLGVLDASECPPTFGVSSEMVKGLISGGLEAITKAKEGAEDSEAMAKQDLLDIKLTEHDTVIGIAASGRTPYVKGALSYANEIGASTVAISNNKNSEIGKIAEIAIEAETGPEVITGSTRLKAGTAQKLILNMISTASMIGVGKVYENLMVDLKPTNKKLVDRSKRIIMEATQVDYTTAENYLQKANNSVKTAIVMILLNCNVDEAIQHLDRAEGFIRKTK
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: RL28_STAES
Sequence: MGKQCFVTGRKASTGNHRSHALNANKRRWNANLQKVRILVDGKPKKVWVSARALKSGKVTRV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: FSLA_DICDI
Sequence: MVDIRKSLFFIIFFIFYNYVNSQKAINSDAFCQKKTITSICDPYLFNTDSIYIFNSTTTQESIELEIKRLLGFFSMLPSTCQVPSTYRLICNQYFQTCVPISKTDNSSTIAIPLRPCRESCDYGNGICGTQSITPCTGTFTEPTIYKFPVTSNVFDLSSLGGPSNYDLQCLNIDTMKAGNLNGTYISNNETVIVNQTCVYPLVYRNSTNREDDIKKGYQYLTETSDCLLPCPVPFFTENEWYQFKDLTTVTGVISFVCIFFNIFIYGFLNKKHDRHTIGILCLSFSLWCCMLSDLIVASSPDYSLVCPEPGRFARIHDSRCVANGIIFQWGAVCTTMFWSAMAIDLYLVIKKLSLPAFTVKYFVAAIFTLALLFTTVPLAWDDYGYGFGGVGCWIMSNSVQNGCFWIPMLICLLIGAVSICLIIYEIVKVFKNVGRSGISIILANARLFGIVSFIFIEYIYLFVYHFWVQENTEKFTQNITDWVICVQTTGSSDGCPLPKAVPYATQFIFLFFLRLLGIEVCIFYGINSRSKNIILESDLVNNKYFKAIRSKISSVGATSTTKNNTSTNNTSDQFNTSMFSVEVSKNGGDDDDL
What are the official names of this protein?
Frizzled and smoothened-like protein A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUVA_LEPCP
Sequence: MIGRLTGTLAEKSPPQLLVDVGGVGYEVDVPMSTFYNLPVLGERVTLLTHFVVREDAQLLYGFLTATERATFRQLLKISGVGARTALSILSGLSVADLAQAVSAQEAGRLVKVPGIGKKTAERLLLELKGKLGPDLALPGAVIRNEAQSDIVQALIALGYNEREAAAAIKPLPADVGVSDGIKLALRALGK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RLF2_SCHPO
Sequence: MNSESVDSDVAASTSNKGNELCSSSTDITSLSVSSPNESVIHSSHSASEADEYVCKLSYEGNRKKRIYNGSAEAGKEKKLQKQRAQEERIRQKEAERLKREKERQQREQEKKLREQEKIAAKKMKELEKLEKERIRLQEQQRRKEERDQKLREKEEAQRLRQEQILNKERQQLKLNNFFTKGVEKRIAPNENFVADKTDELNEFEKEFRPFFIKHQMSLSKYPSPNESDSFLDEVLSTSKSYPLKLNDIFTPSDAVSSANSLGVSNRNSENEVRQLMSAYQDPSVSKPQEILSCLSQIPIKFIFFYQDVRPPYFGSYTKTHSHGSNVLLNPWLEDEDIDYTYDSEAEWVADEEDDGEDLESEDEEVDNSDDIVEDGDNAFVDDEDDDKDSVNASNTHRSSGPLEVIVEGPVWDSKFLPDFNCLSLIEPISSFSASTYLQIDPKEDLWASQDTAPASSGMTIGPTSSLSDDLQVRFPSEDIPKFIEYVRNSHDNKVFLIENLRHMFPYVTKNIISETLGKVAVRKGKSVSDGWIIKENFASLLSS
What is the function of this protein?
Acts as a component of chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto replicating DNA in vitro.  It performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer.  May facilitate the efficient and timely assembly of histones into telomeric chromatin (By similarity).
What are the official names of this protein?
Chromatin assembly factor 1 subunit rlf2.
What is the protein family that this protein belongs to?
Belongs to the RLF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPH_CALS4
Sequence: MNRIDGREFNELRPIKITRNFNKFAEGSVLIEMGETKVICTASIEDKVPPFQKGTGKGWITSEYGMLPRATEVRNPREVTKGRPSGRTMEIQRLIGRSLRAVVDLEALGERTIWIDCDVIQADGGTRTASITGSFIALADALNKLVEKGELQKIPLKSFVAAVSVGIVEGNKLLDLSFQEDANALVDMNVVMTDKGEIVEIQGTGEGGPFSRQNFEELLDLAAHGIEQIIKIQKEVLSDIADKIGVENVEVDSGNSQSQQG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: DTD_LYSSC
Sequence: MKVVLQRSKAASVTVDGTVTGAIDSGYVLLVGITHEDTQEDVAYLAKKVANLRLWEDADGKMNHSILEQGGAILSVSQFTLYGDAKKGNRPSFTSAARPEVAEPLWEAFNQALREHGLHVETGIFGAMMDVALINDGPVTILLESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPH_ACIB3
Sequence: MRIDQRALDQLREVKITRNYTRYAEGSVLVEFGHTKVLCTASIDNSVPRFLKGQGQGWVTAEYGMLPRSTHSRCDREAARGKQTGRTQEIQRLIGRSLRAMVDLKKLGENTITIDCDVIQADGGTRTASITGAAVALVDAMNVLLAQKKIKQDPLKGLVAAISVGMYQDEVLLDLCYEEDSNCQTDLNVVMTQAGEFIEIQGTAEDKPFTRAQSNAMLEMAEKGIAELIKKQQEALGW
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RECU_STRPI
Sequence: MVNYPHKLSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQGLAVIHKKPTPIQIVRVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEAKETKQKRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPALDLIRFYHQDKGQKSMPLGYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR
What is the function of this protein?
Endonuclease that resolves Holliday junction intermediates in genetic recombination.  Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands.  Promotes annealing of linear ssDNA with homologous dsDNA.  Required for DNA repair, homologous recombination and chromosome segregation.
What are the official names of this protein?
Holliday junction resolvase RecU, Recombination protein U homolog.
What is the protein family that this protein belongs to?
Belongs to the RecU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORC4_ARATH
Sequence: MGKETPAEKSLNLIRGRLCDPSYVFRPLSASSDSNYSKLKFIVSTSITEGCNNSMLLLGPRGSGKAAVLDLGVGDLLEQFPDSVSVIRLNGLLHSDDNCAFKEIAKQLCMEHHLLFSKMASFDDNSQFIIAMLRACGLAHKTIIFVLDEFDMFAQGKQRLLYSLLDAMQSVTSQAVVVGISSRLDADQLLEKRVRSRFSHRKFLFLPPSREELDGLFVHLLSLPADSGFPSGYVSRFNDKIKNLTSDTRFKDILKTLFNANSTVNSFLKFIFCAVSLMNLESGLLSLENFKAALSSMQRQPKLEAVRDCSVLELYLLVCMRRLEVKEQSSYNFISVMKEYKAIHDSFHTSDYYAQNVCLRAFEHLRERQVICYAENRGQSQTGEYRLQKLLISASELHQGMRSHACCPAILLKLLDH
What is the function of this protein?
Component of the origin recognition complex (ORC) that binds origins of replication.  DNA-binding is ATP-dependent.  The specific DNA sequences that define origins of replication have not been identified yet.  ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
What are the official names of this protein?
Origin of replication complex subunit 4, AtORC4.
What is the protein family that this protein belongs to?
Belongs to the ORC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WDCP_HUMAN
Sequence: MELGKGKLLRTGLNALHQAVHPIHGLAWTDGNQVVLTDLRLHSGEVKFGDSKVIGQFECVCGLSWAPPVADDTPVLLAVQHEKHVTVWQLCPSPMESSKWLTSQTCEIRGSLPILPQGCVWHPKCAILTVLTAQDVSIFPNVHSDDSQVKADINTQGRIHCACWTQDGLRLVVAVGSSLHSYIWDSAQKTLHRCSSCLVFDVDSHVCSITATVDSQVAIATELPLDKICGLNASETFNIPPNSKDMTPYALPVIGEVRSMDKEATDSETNSEVSVSSSYLEPLDLTHIHFNQHKSEGNSLICLRKKDYLTGTGQDSSHLVLVTFKKAVTMTRKVTIPGILVPDLIAFNLKAHVVAVASNTCNIILIYSVIPSSVPNIQQIRLENTERPKGICFLTDQLLLILVGKQKLTDTTFLPSSKSDQYAISLIVREIMLEEEPSITSGESQTTYSTFSAPLNKANRKKLIESLSPDFCHQNKGLLLTVNTSSQNGRPGRTLIKEIQSPLSSICDGSIALDAEPVTQPASLPRHSSTPDHTSTLEPPRLPQRKNLQSEKETYQLSKEVEILSRNLVEMQRCLSELTNRLHNGKKSSSVYPLSQDLPYVHIIYQKPYYLGPVVEKRAVLLCDGKLRLSTVQQTFGLSLIEMLHDSHWILLSADSEGFIPLTFTATQEIIIRDGSLSRSDVFRDSFSHSPGAVSSLKVFTGLAAPSLDTTGCCNHVDGMA
What are the official names of this protein?
WD repeat and coiled-coil-containing protein.