PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_THEMA
Sequence: MRIKRLPESLVRKIAAGEVIHNPSFVLKELVENSLDAQADRIVVEIENGGKNMVRVSDNGIGMTREEALLAIEPYTTSKIESEEDLHRIRTYGFRGEALASIVQVSRAKIVTKTEKDALATQLMIAGGKVEEISETHRDTGTTVEVRDLFFNLPVRRKSLKSSAIELRMCREMFERFVLVRNDVDFVFTSDGKIVHSFPRTQNIFERALLILEDLRKGYITFEEELSGLRIKGIVSSREVTRSSRTGEYFYVNGRFVVSEELHEVLMKVYDLPKRSYPVAVLFIEVNPEELDVNIHPSKIVVKFLNEEKVKKSLEETLKRNLARKWYRSVAYEEISSRALSVAEAPSHRWFLVKGKYAVVEVEDGLLFVDLHALHERTIYEEILSKKSWGKRRVKRNITVVLSREEKQKLEEYGFSFQGEEGALKVIEIPEFLTEDVVEEFFRDFPVDEKLKERIALAACKLATKSGEFDEEIASKLLDVFFKKRFERCPHGRPISFKISYEDMDRFFER
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: GPN2_SCHPO
Sequence: MPFCQVVVGPPGSGKSTYCFGMYQLLSAIGRSSIIVNLDPANDFIKYPCAIDIRKVLDVEMIQKDYDLGPNGALIYAMEAIEYHVEWLLKELKKHRDSYVIFDCPGQVELFTNHNSLQKIIKTLEKELDYRPVSVQLVDAYCCTNPSAYVSALLVCLKGMLQLDMPHVNILSKADLLCTYGTLPMKLDFFTEVQDLSYLAPLLDRDKRLQRYSDLNKAICELVEDFNLVSFEVVAVENKASMLRVLRKIDQAGGYAYGSTEIGGDAVWVNAVRQGGDPLQGISPQERWIDKKEEYDKYEWELEQKSTMDEDENEG
What is the function of this protein?
Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 2, ATP-binding domain 1 family member B homolog.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RR16_SACOF
Sequence: MVKLRLKRCGRKQQAIYRIVAIDVRSRREGRDLRKVGFYDPIKNQTCLNVPAILYFLEKGAQPTRTVYDILRKAEFFKDKERTLS
What are the official names of this protein?
30S ribosomal protein S16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CH10_RHOCA
Sequence: MAFKPLHDRVLVKRVQSEEKTKGGLIIPDTAKEKPAEGEVVAVGAGARKDSGELIAPAVAVGDRILFGKWSGTEVTLDGVEMLIMKESDIMGIIS
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_LACSA
Sequence: MRMNPTTSGSGVTTLDKKTLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTAGQPINVTCEVQQLLGNNRVRAVAMSATDGLTRGMDVIDTGAPLSVPVGGATLGRIFNVLGEPVDNLGPVDTSTTFPIHRSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNIPESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYDTAQEVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFQLILSGELDGLPEQAFYLVGNIDEATAKAMNLEMESNLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: I1B5_CONRA
Sequence: GAVPCGKDGRQCRNHADCCNCCPIGTCAPSTNWILPGCSTGQFMTR
What is the function of this protein?
Iota-conotoxins bind to voltage-gated sodium channels (Nav) and act as agonists by shifting the voltage-dependence of activation to more hyperpolarized levels.  Produces general excitatory symptoms (By similarity).
What are the official names of this protein?
Iota-conotoxin-like R11.5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: THIL_PYRCJ
Sequence: MSGFGGRGVDEKGFLRWLLGELGVEEDDVAYVDGLVVKVDGAAASTSRLPFQTWADFGWRNVAAAYSDVRVKFAEARLLLASVTAPDLGTAAEVVQGVREASQFFSLAYVGGDLNEGRDVVVDVVLVGWARARVGRAPRPGDVLVTIPQFGYTSLAYRFWQMGGAVVERGVEALKRPKPLWPLPPAECVTAAMDSSDGLGDVLWSMARGVDIVVKELPAPREVLEFAAERGLDVGEIVFNGGEEFLPVFAVRRDCPVESPYVSFAEVVPGEGRVWWRGEELKWRGWAYFRGWG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
What are the official names of this protein?
Thiamine-monophosphate kinase, TMP kinase, TP kinase, Thiamine-phosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-monophosphate kinase family.
Protein: RL20_CAUSK
Sequence: MARVKRGVTAHAKHKKVLEQAKGFYGRRKNTIRTAKAAVDKAGQYAYRDRKVRKRAFRSLWIQRINAGARVEGFTYSQFIHGLDVAGIVIDRKVLSDIAGQDPVAFKAIADKVRAALAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: NU3C_NANDO
Sequence: MFLLHEYDIFWAFLIISSVIPILAFLISGVLAPISEGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVSVFIEALIFVLILIVGLVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: AROQ_CLOBH
Sequence: MNNILVINGPNLNLLGKREPDIYGNITLENINQKIKLHFKNEDLKIDFFQSNEEGKIIDKIIESEKKYNAIVINPAAYSHYSIAILDAMRSINIPVVEVHLSNIYKREEYRKKSVTAEASLGVISGFGYYGYIMAIEFILNNLVRER
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: GVPM1_HALSA
Sequence: MEPTKDETHAIVEFVDVLLRDGAVIQADVIVTVADIPLIGISLRAAIAGMTTMTEYGLFEEWDAAHRQQSEAFTTSPTADRRED
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  This protein could be important for the shape determination of the gas vesicle.
What are the official names of this protein?
Gas vesicle protein GvpM 1.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: ISDC_STAAS
Sequence: MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKNSASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE
What is the function of this protein?
Involved in heme (porphyrin) scavenging.  Binds hemoglobin and almost exclusively free-base protoporphyrin IX.  Probably has a role as the central conduit of the isd heme uptake system, i. e.  mediates the transfer of the iron-containing nutrient from IsdABH to the membrane translocation system IsdDEF.  Hemin-free IsdC (apo-IsdC) acquires hemin from hemin-containing IsdA (holo-IsdA) probably through the activated holo-IsdA-apo-IsdC complex and due to the higher affinity of apo-IsdC for the cofactor.  The reaction is reversible (By similarity).
What are the official names of this protein?
Iron-regulated surface determinant protein C, Staphylococcal iron-regulated protein D.
What is the protein family that this protein belongs to?
Belongs to the IsdC family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan- anchor. Note=Anchored to the cell wall by sortase B (By similarity).
Protein: USPF_SHIFL
Sequence: MNRTILVPIDISDSELTQRVISHVEAEAKIDDAEVHFLTVIPSLPYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILELAKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR
What are the official names of this protein?
Universal stress protein F.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
Protein: MPIP1_RAT
Sequence: MELGPEPPHRRRLLFTCSPTPAPQPTGKVQFGASRAGGLSPVTNLTVTMDQLEGLGSDYEKPMDVRNSSSLQRMGSSESTDSGFCLDSPGPLDSKENLEISLRRINCLPQKLLGCSPALKRSHSDSLDHDIFQLIDQDENKENEAFEFKKPIRPASRGCLNAHVHEESKDPFTHRQNSAPARMLSSNESDISESGNFSPLFTPQSPVKASLSDEDDGFIDLLDGENLKNDEETPSCMSSLWTAPLVMRRPTNLADRCGLFDSPSPCSSTSSCSTRAVKRADRSHEESPRGTKRRKSSEASPVKADVPEPTQLPHQSLSLTSFPKGTIENIFHSDPRDLIGDFSKGYLFHTVSGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEEFLLKKPIVPADGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQSHCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
What is the function of this protein?
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression.  Directly dephosphorylates CDK1 and stimulates its kinase activity.  Also dephosphorylates CDK2 in complex with cyclin E, in vitro (By similarity).  Phosphorylation by PIM1 leads to an increase in phosphatase activity.
What are the official names of this protein?
M-phase inducer phosphatase 1, Dual specificity phosphatase Cdc25A.
What is the protein family that this protein belongs to?
Belongs to the MPI phosphatase family.
Protein: LEXA_VERSI
Sequence: MLTERQQELLDFLRVYQRQQGVMPSTRDIQLHFGFASQTAAMSHLKALERKGVIRRLAGKARAVVFPEVMERETVDIPIFGLIPAGFTADNPEHSDGNLTLDLRTMGLSPRSKPFALKVRGDSMTGAHIIQGDYVILEQRDPRPKDIVAALMDGETTLKRYLVDNGQPFLRAENPSYPDLIPARELMIQGVMVGLFRPYNGR
What is the function of this protein?
Binds the consensus sequence 5'-TGTTC-N(4)-GAACA-3'; some genes have a tandem consensus sequence, at high concentrations their binding is cooperative (PubMed:27489856).  Binds to the promoters of a number of genes, including dinB, imuA, lexA, recA, recQ, splB and uvrA (PubMed:27489856).  Represses a number of genes involved in the response to DNA damage (SOS response) (By similarity).  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: WDR4_XENTR
Sequence: MLRLGSSGLALTGSSRVLGHRAGSECPPFHLDCSSLEKQSAAPGQEGSVDPQGSDKILAAAFSPSGEYFALTDDNKRLILFQTKPAWETISVRWVSRRCTALTFSPCGAHILVADKSGDVFSFSVRRSREAGRLELGHLSMLLDVAVSPDGNHIITCDRDEKIRVSRWDSPHVIMSFCLGHTEFVSQLLPLPGADKLLLSGSGDGTLRLWDYESGREVQSVTLSGLDLGMERQENKRFTVSRISCCACNGIQLAMLCEGVPGIFLFSVAPGPRLTLTQYVALTHTPLDLDFDGSAYLWVLSGDWEEPLLKYKELNGQWQSVVNDEEVTRLSGFIRENWADLEGAGAPENRFAVLYKAVVDNMATYLQKKELRLENEKRKTTEGQVAPASKVQKTEC
What is the function of this protein?
Non-catalytic component of the METTL1-WDR4 methyltransferase complex required for the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs).  In the METTL1-WDR4 methyltransferase complex, wdr4 acts as a scaffold for tRNA-binding.  Required for the formation of N(7)-methylguanine at position 46 (m7G46) in a large subset of tRNAs that contain the 5'-RAGGU-3' motif within the variable loop.  M7G46 interacts with C13-G22 in the D-loop to stabilize tRNA tertiary structure and protect tRNAs from decay.  Also required for the formation of N(7)-methylguanine at internal sites in a subset of mRNAs.  Also required for methylation of a specific subset of miRNAs.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit wdr4, WD repeat-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y480_LIMRJ
Sequence: MKIIISPARTMQVDTDSLLYKDLPEFLQQTKDILGWMRSLSYDELHKVWGNCSSRLAMKNYQWLQQMDLQRKLTPAIIAFTGLQYQYMAPSVFSEDGLKYVQDNLRILSGFYGILRPFDGIIPYRLGMGDMAPVNGYKNLYDFWGEQLYHELYKNNDLVISLASVEYEKAITPYLQTQDRFIKCIFGEEINGKIKQKATLAKMARGNMVRYLAENQIQTIEGVKQFNIGGYRFREDLSTDEKLVFELVK
What are the official names of this protein?
UPF0246 protein LAR_0480.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: HBEAG_HBVA8
Sequence: MQLFHLCLIISCTCPTIQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGDVTNLATWVGTNLDDPASRDLVVNYVNTNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRDRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: CPSF2_ORYSJ
Sequence: MGTSVQVTPLSGAYGEGPLCYLLAVDGFRFLLDCGWTDLCDPSHLQPLAKVAPTIDAVLLSHADTMHLGALPYAMKHLGLSAPVYATEPVFRLGILTLYDYFISRRQVSDFDLFTLDDIDAAFQNVVRLKYSQNHLLNDKGEGIVIAPHVAGHDLGGTVWKITKDGEDVVYAVDFNHRKERHLNGTALGSFVRPAVLITDAYNALNNHVYKRQQDQDFIDALVKVLTGGGSVLLPIDTAGRVLEILLILEQYWAQRHLIYPIYFLTNVSTSTVDYVKSFLEWMNDSISKSFEHTRDNAFLLKCVTQIINKDELEKLGDAPKVVLASMASLEVGFSHDIFVDMANEAKNLVLFTEKGQFGTLARMLQVDPPPKAVKVTMSKRIPLVGDELKAYEEEQERIKKEEALKASLNKEEEKKASLGSNAKASDPMVIDASTSRKPSNAGSKFGGNVDILIDGFVPPSSSVAPMFPFFENTSEWDDFGEVINPEDYLMKQEEMDNTLMPGAGDGMDSMLDEGSARLLLDSTPSKVISNEMTVQVKCSLAYMDFEGRSDGRSVKSVIAHVAPLKLVLVHGSAEATEHLKMHCSKNSDLHVYAPQIEETIDVTSDLCAYKVQLSEKLMSNVISKKLGEHEIAWVDAEVGKTDDKLTLLPPSSTPAAHKSVLVGDLKLADFKQFLANKGLQVEFAGGALRCGEYITLRKIGDAGQKGSTGSQQIVIEGPLCEDYYKIRELLYSQFYLL
What is the function of this protein?
CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition.
What are the official names of this protein?
Cleavage and polyadenylation specificity factor subunit 2, Cleavage and polyadenylation specificity factor 100 kDa subunit, CPSF 100 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYSY_METNO
Sequence: MRAYHDLLRRILDDGVAKHDRTGTGTLSVFGHQMRFDLAEGFPLVTTKRLHLKSIIHELLWFLAGDTNVAYLQSNGVTIWDEWADEHGDLGPVYGRQWRSWAKPDGGSVDQIAWVLDEIRRNPDSRRLVVSAWNPADLDRMALAPCHCLFQFYIAERRLSCQLYQRSADAFLGVPFNIASYALLTAMMAHVLDLEPGDFVHTLGDAHLYSNHVAQARQQLARDERPLPRLRLNPEVRSLFDFRYDDVVIEGYDPHPAIRAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGMB_DICDI
Sequence: MKVKAPILLLFVFLINFCFSIKQTQQQNFDITIDNNNYNNNNNNNKNEIINNNNKNNNNLNDEYFEKLGYDTNGTKCDICKFGINQVQKMIASKQGIEDISKYAIDLCTYLHIEKAEVCNGLIPLFANMTYNVLSYPTVTGEYVCGFVGFCPYVPRNSSNIINFPKPKPPHVPPVAPSPNSPTMKILHISDIHVDPVYESGMNADCGEPLCCRAPNGPGVGEKAAGEWGHYLCDINMKMVESMFEFIDQEFGEDIDIVFWTGDNPPHDIWEQTYDSQINASQLVTNLVKKYFGSTAKVFPAIGNHESLPVNSFPLPPGSSWIFNALSYDWSDWVNVDEQVANLQYGGYYTLPVQSGLRVISLNMNWCNNGNLYLAENSTDPANMLQWIVDTLQASEDIGEKVYLVGHIPPGIPDCIDSWSEQLLQIVNRYEDTILASFYGHTHRDEFSVYYTQSDENDPSSPMRASNVIYTTPSVTTYQHQNPSFRIFTVDSNTGYLMESSTYHTDLSQANLNGKPTWLLEYNTTNTYNIPNLTPISMDLAIQNINSSNSMLEDYHVHYYSASPYPESKPCTSISCKLDYICKMKSAAYLKYYECIHHEVNNYLLNESDDDSIKSHKKLNILLDLNNYLNNEVLKSC
What is the function of this protein?
Converts sphingomyelin to ceramide.
What are the official names of this protein?
Sphingomyelin phosphodiesterase B, Acid sphingomyelinase B, aSMase B.
What is the protein family that this protein belongs to?
Belongs to the acid sphingomyelinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: FABH_SALTI
Sequence: MYTKIIGTGSYLPEQVRTNADLEKMVETSDEWIVTRTGIRERHIAAPNETVATMGFTAANRAIEMAGIDKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALSIADQYVKSGVVKHALVVGSDVLARTCDPGDRGTIIIFGDGAGAAVLSASEEPGIISTHLHADGRYGELLTLPNADRVNPDNPIYLTMAGNEVFKVAVTELAHIVDETLAANNLDRSELDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKAGQLVLLEAFGGGFTWGSALIRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WGN_DROME
Sequence: MMPPRLPGGHGGAMRSRSSSSGHHLNTTFHKRRRRRQQHHIGGSHISISHGSYLALLLLSTTCSLVATSASSSSSAANTDIAPPDPPPVSQVSIASSSPCAPQHWWDSQRDRCTPCTRCQGEMIPLRPCQLHTDTICGSIYDLKIDWVVLAKTEPNWKERRKSSEYEHFEHNAPLQHLTHEQLQQLHEEAAAAWVLDWQTGVLYVAVLTCLVFFSVAACILIHHMRQWRRMERRLDQDVEELSTKLMAKLAEVQSLDGGTFFIGNADALRGLPASAATTHPATTQSGIFQPQHVLLPEKRGKHQERRILKTLQPGNVYIEESNAGLGGMGVGLGVRGCSGLKG
What is the function of this protein?
Receptor for egr (PubMed:12084706, PubMed:12894227).  Involved in induction of apoptosis by triggering JNK signaling (PubMed:12894227).  Mediates the tumor suppressor activity of egr which eliminates oncogenic cells from epithelia, thereby maintaining epithelial integrity (PubMed:19289090).  Following UV-induced epidermal damage, binds to egr released from apoptotic epidermal cells and plays a role in development of thermal allodynia, a responsiveness to subthreshold thermal stimuli which are not normally perceived as noxious (PubMed:19375319).  Together with Moe, involved in control of axon targeting of R8 and R2-R5 photoreceptors, independent of egr (PubMed:23544124).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member wengen.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PSBI_WELMI
Sequence: MLTLKVFVYTVVTFFISLFLFGFLSNDPGRNPGRKEEG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HIS3_CLAMS
Sequence: MSAAPLDPRGHGDPDVDGILARASFADDGLLPAVIQQHDTREVLMLGYMDREALRRTLTTGRVTFWSRSRSEYWRKGDTSGHGQYVRDAALDCDGDTVLVQVDQVGVACHTGTRTCFDADHLHPVTGARPAADEGPTP
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_ECO24
Sequence: MKPYQRQFIEFALGKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGLEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRSEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: SYC_SULSY
Sequence: MSLKIYNTLTGKKEDFAPIKPGEVKIYTCGVTVYDYNHVGHGRSLIVFDMIRRYLRYLGYNVIFVRNFTDVDDKIINRAKNECLPFSVISDKFIKEYFDDAEKFRIEPADIEPRVTTHIPDIINFIQKLVDAGYAYEADGDVYFSVRKFKEYGKLSKRSIDELLAGARIEPGEKKKDPLDFALWKSAKAGEPYWESPWGKGRPGWHTECCAMIFKHLGETIDIHGGGLDLTFPHHENEIAQAEALTGKPFARYWIHNGLVTVNGQKMSKSLGNYIKLKEIYSKYEPDILRLLVLSVHYRSPLDFSWDKMEETKKAYERLKNAIEEAEVLNKLPIDENFEGDLYNAIQKAQSGFYSAMSDDFNTPEALASLFGLVREMNILRDKAIKHGGISKKAIESYKEAAKTLHDIGRDIFGLFDSLQPCIKQEEVKVKEKEESINEDLIQVLIEAREKARKEKQFTIADLIRDKLAEKGIILEDAPFGTKWKKA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.