PharMolix/UniProtQA huggingface dataset:
Protein: RNZ_STRZT
Sequence: MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQNRILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFVLTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLEGTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTRKTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHISARFLSKDISKLKKDAATIFENVHVVKDLEEVEI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: RECO_YERP3
Sequence: MDGWQRAFVLHGRPYSETSLMLDLFTEGEGRMRVLAKGARGRRSNLKGCLQPFTPLLVRWSGRGEVKTLRSAEPVSLALPLSGSMLYSGLYVNELLSRVLEHQTSYSALFFDYLHCLQALAGSDGSPEHALRQFELAMLANLGYGVDFLHCAGSGQPVSDTMTYRYREEKGFIASLVVDHYSFTGRQLLALANREFPDADTLRAAKRFTRIALKPYLGGKPLKSRELFRQFVIKPPADPSP
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: LPXC_MYXXD
Sequence: MRPSSYNQRTLSKIASLQGVGLHSGARVTLTLRPAPPGHGIVFVRTDLARPVSIPALAEYVVDTSLATTLGRDGVRVGTVEHLMAALAGMGIDNLRVELDGPEVPIMDGSAAPFAALIQSAGVREQEAPKELLVIRKAVSVVDGDKQASLTPARHFRISCTIDFEHPVIQGQSFDLDFGDRDFAREISRARTFGFLRDVEKLKQMGLARGGSLENAIVVDEVSILNPDGLRFPDEFVRHKILDAIGDVSLFGRPVIGHMTAYKTGHALNHKLVRKVMSDPSCYEIVPARRRELEGMGLGFSGLAGALDFEPLVA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: MAO2_ARATH
Sequence: MMWKNIAGLSKAAAAARTHGSRRCFSTAIPGPCIVHKRGADILHDPWFNKDTGFPLTERDRLGIRGLLPPRVMTCVQQCDRFIESFRSLENNTKGEPENVVALAKWRMLNRLHDRNETLYYRVLIDNIKDFAPIIYTPTVGLVCQNYSGLYRRPRGMYFSAKDKGEMMSMIYNWPAPQVDMIVITDGSRILGLGDLGVQGIGIPIGKLDMYVAAAGINPQRVLPIMLDVGTNNEKLLQNDLYLGVRQPRLEGEEYLEIIDEFMEAAFTRWPKAVVQFEDFQAKWAFGTLERYRKKFCMFNDDVQGTAGVALAGLLGTVRAQGRPISDFVNQKIVVVGAGSAGLGVTKMAVQAVARMAGISESEATKNFYLIDKDGLVTTERTKLDPGAVLFAKNPAEIREGASIVEVVKKVRPHVLLGLSGVGGIFNEEVLKAMRESDSCKPAIFAMSNPTLNAECTAADAFKHAGGNIVFASGSPFENVELENGKVGHVNQANNMYLFPGIGLGTLLSGARIVTDGMLQAASECLASYMTDEEVQKGILYPSINNIRHITAEVGAAVLRAAVTDDIAEGHGDVGPKDLSHMSKEDTVNYITRNMWFPVYSPLVHEK
What is the function of this protein?
Involved in the regulation of sugars and amino acids metabolisms during the night period.
What are the official names of this protein?
NAD-dependent malic enzyme 2, mitochondrial, AtNAD-ME2, NAD-malic enzyme 2.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NADD_GEOTN
Sequence: MGKIGIFGGTFDPPHYGHLIMANEVLDALQLSQIWFLPNRIPPHKQNEQVTRSEDRLRMLELAVAGHPRFHIETIELEREGPSYTYDTIRQLTAMHPDDEFYFIIGADMVEYLPNWHRIDELIELVTFVGVKRPGFSMETPYPVIEVEVPQFAISSSLIRERVQNGQTIRYLVPEGVRLYIEEKGLYGARTSVADCERAADGTSLRAYAWRCRDGC
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: TRUA_BURM7
Sequence: MMRIALGIQYDGAAFCGWQSQPHGKTVQDALERSLAEFAQTSLHTTVAGRTDTGVHGLGQVVHFDTDLDRADFSWVRGTNAFLPPTVAVQWAKPMPDTFHARFAAFERTYYYALYVHPVRSPMLAGRAGWVHTPLDVDAMREAAAHLVGEHDFSAFRSSECQAKSPVKHLYQIGIRPDGDFIHFRFRANAFLHHMVRNLMGCLVAVGRGRYPSSWLAEVLESRDRDCAAPTFMPEGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDGRT
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: KSRA_CAEEL
Sequence: MMQTQVASRAGYSNLPQFGAGIAQDIKTQAINNLKECLKLTTINRFLTSSYEEDAKSVERKIFSAVYQMTKIGLIDREKREINAIWFTFVGLSAQNIRHLEICSITDFNALFSITNQELRSLADRGRLDVETKRKLLQSTVILQNHWNAYHSRTSSGSTDEPSGQSTPAIVTPSPKFNVPSLSVTSAKMIQSSSMGFATTPKSPKTSSRLVHAIPHKWHRSTKFRFSGDAVCHFCQRPLGFGFLNAWEKCRSCKWKVHTQCKGRVGDSCGLTPDHLRFLFDKLIQENNGGMWKDPQSVPGSRSMNEPAFQFPDTAIDSSSSTNSSAPSTPALPAGISGNVSSLTAPYRSERKFLFPDTENYSVHNRLPILVISEGDHPTTTEIQQETENHNKSAAASMSGNIESEGTIVANHEDSTGSQEVDSEAAPSQEAVDKFNKRADGGFTWERHAWNMSTIRGPNAQASWNEVTIQFETIEFDKQAPIIGRGRFGKVLRGFHYGDVAVKVYTMEHISDASKKAEEFKLEVSAYKNTRHDNIALFLGYFMSDGQYGMVMSLSKGSQSLYTLLHVVREKLDLATTRKIAQQICQAVSYLHTKKILHKDLRSKNILLESKNKVVITDFGILSMKRLAHPKQKSGYLTSKFWTNYIAPELAMAMRTEYDEYECDDFPFSENSDVYAFGCVWFEMLTGALPYAGELPHQILFAKTQGIRPVLPNVKCTQELKELLVSCWNTAPQDRPTLTDINLKLTALPKKPRVNRSPSFPVMMKSYESTF
What is the function of this protein?
Serine/threonine-protein kinase which positively regulates Ras-mediated signaling probably acting at the level of let-60/ras or/and lin-45/raf.  Involved in sex myoblast migration (PubMed:8521513, PubMed:11882296).  Plays a role in responses to M. nematophilum-mediated bacterial infection by promoting tail swelling and preventing constipation (PubMed:15268855).  Functions redundantly with ksr-2 in the Ras-mediated regulation of larval survival, the development of excretory canal and in mpk-1 phosphorylation in somatic cells (PubMed:8521513, PubMed:11882296).  In addition, involved in determining vulval precursor cell fate during vulval induction independently of its kinase activity (PubMed:8521514, PubMed:8521513, PubMed:10409742, PubMed:11882296).  Plays a role in egg-laying (PubMed:23900546).
What are the official names of this protein?
Kinase suppressor of Ras A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Protein: LEPA_MYCCT
Sequence: MDKSKIRNFSIIAHIDHGKSTLADRILELTNTVEKREMQDQLLDSMDIERERGITIKLNSVQLKYHSKDDKDYIFNLIDTPGHVDFTYEVSRSLAACEGAILVVDASQGVEAQTLANVYLAIDSNLEIIPVINKIDLPSADVDKVKQEIEEIIGLDCSNAPLISAKTGLNVQDVLQAIVDKIPPPSDAIDNAPLKALIFDSYYDKYLGVVMSIRLKQGMLKVGDKIKLMSTNAEYEVTSLGIKTPKIVKKDFLEAGEVGWVAASIKTIKDVNVGDTITSVLNPAKEPLDGYKKLKPMVYCGIYPIDTNKYQDFKEALEKIELSDSSLVYEPETSQALGFGFRCGFLGLLHMEVIQERLEREYNLELIATAPSVVYKVHLTNKQVIELDNPALLPEAQKISKIEEPFVEIKIATPSEYIGDLMNLCQNKLGIYKNMEVIDNNRRILIYQMPLAEIIFDFFNKLKSISKGYASFEYELIGYKESKLVRMDIKLNGEMVDAFSMIVNQKFAYQRGSALTLKLKELIPRQNFEVPVQATIGNKVISRETIKAYRKDVTWKLHAADKSRRKKLLEKQKEGKKKMKEIGTVEVPQEAFVAILKIDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PANB_PARL1
Sequence: MSVQSKIKRVTVPEIRARKGAEPIVSLTAYHAHTARYIDPYVDFLLVGDSLGMVMYGMETTLGVTLDMMIAHGAAVVRGTERALVVVDMPFGSYEESPEIAFRNACRVIKETGCTAVKLEGGTRIAETIRYLTLRGIPVMAHIGLTPQNIQVMGGFKTQGREEGEWAAIEADAKAVAEAGAFAVVLEGMAEPLAARITGQIDIPTIGIGASPNCDGQILVLEDMLGLSPRPAKFVREFATLGAQIAGAAEAYARAVRERSFPAAEHTYSMKKAK
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y637_MYCTO
Sequence: MALKTDIRGMIWRYPDYFIVGREQCREFARAVKCDHPAFFSEEAAADLGYDALVAPLTFVTILAKYVQLDFFRHVDVGMETMQIVQVDQRFVFHKPVLAGDKLWARMDIHSVDERFGADIVVTRNLCTNDDGELVMEAYTTLMGQQGDGSARLKWDKESGQVIRTA
What are the official names of this protein?
UPF0336 protein MT0666.
What is the protein family that this protein belongs to?
Belongs to the UPF0336 family.
Protein: Y142_CAUVN
Sequence: MAAGVRQSRGTAARKVGRRAEVIAALWLMAKGYRILGFRLATPLGEIDLLAQRGKVLAVVEVKQRTTIEDALDAVKPTQRERLRRAATHLAAHRAGLRDLLVRLDLIAMAPGRPPRHLPDAWGGA
What are the official names of this protein?
UPF0102 protein CCNA_00142.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: FLIS_CAMJ8
Sequence: MQNNLAYNAYSQNQAGIESPQKLIEMLYEGILRFCARAKVAIRNEDIEQRVYFVKRTTAIFIELINTLDYEKGGEVAHYLSGLYTREIQLLSLANLENNEDRINEVINVTKGLLEAWREVHNNETVAQ
What is the function of this protein?
Required for flagellar assembly and thus bacterial motility (PubMed:28659885).
What are the official names of this protein?
Flagellar secretion chaperone FliS.
What is the protein family that this protein belongs to?
Belongs to the FliS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: YEXB_SCHPO
Sequence: MNHNVYLLTSFNLWSHGVYKISSISLSNSFFPHSFMFVKSLHLMTSQHIFKCLSSCNYALSILHNICLASFLYLSKCYYHTHILTSVRLDFCKSHAHTYIKSKAST
What are the official names of this protein?
Putative uncharacterized protein C1A6.11.
Protein: PYRD_ECOSM
Sequence: MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVTHI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AV2_TYLCC
Sequence: MWDPLLNEFPETVHGFRCMLAIKYLQLVENTYSPDTLGYDLIRDLISVIRARDYGETSRRYCHFHSRLEGASPAELRQPLYGSCCCPHCPRHQKTNVVKQAHVPEAHDVPDVQKP
What is the function of this protein?
Through its interaction with host SGS3, acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.
What are the official names of this protein?
Protein V2.
What is the protein family that this protein belongs to?
Belongs to the geminiviridae protein AV2/V2 family.
What are the subcellular locations of this protein?
Host cytoplasm, host perinuclear region. Note=Accumulates in inclusion bodies in the cell periphery. May interact with the ER network from the perinuclear region out to the cell periphery (By similarity).
Protein: MIAA_MARN8
Sequence: MIPDNRSQQGSLPPTIFLMGPTASGKTDLAIELCRTLPCEIISVDSAMVYRGMDIGTAKPSPEELALAPHRLIDICDPADTYSAADFRRDALAAMSEISGRGRIPLLVGGTMMYFKALLHGMSNLPSANQALRAEIEREAERDGWGALHEELAEKDPDAARLIHPNNRQRLMRAIEVIRLTDKPISSFWQSESGTSGQHPQSGIEDYTYFTSWQADESAGLPYTVFQFALAPAERSVLHSRIQKRFLAMLEAGFLDEVRALMARGDLSPDLPSMRCVGYRQAWDYLSGNEDYDSFVAKGVAATRQLAKRQLTWLRKWRDVHWLDSADPQVVLDTLKKSGLHTTFNFE
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SECB_RICPU
Sequence: MSTINTDTNKTMPHISVNAQYIKDLSLENPSAPSSLAALDQRPQIDLSLDINITNLSEENFYEVELNIEAIARNEKYKLFQIELKYAGVFNLINIDSEQHPVLLSVHCPAMIFPFARKIIASCTQDAGFQPLMIDPIDFGALYHKKMSEHQN
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1D1_BOVIN
Sequence: MEASASNPPSTSPETSASTPETPPGPEQLDEEQVKKAVEALLAHSRSRKNANGLLLNENENFFLMVVLWKIPSKELRVRLSLPHGIRSDLADVCLFTKDEPNLSSEQTERYYKKLLNNHGIKTISQIIPFRTLKKEYKAYEAKLRLLGSFDFFITDARIRRLLPSHLGRHFYNRKKVPVSVNLQSKTLSREINDCIGGTVLNISKSGSCSTIRIGHTGMPIQHIVENVVAVAKSLSQKLPEKWESVKLLFVKTERSVSLPVFSSFVSSQGEAKGLRTRDLLKKVSKKSRKKTERALKRQQEKKEKKLLKQAAKAKPAPTTDAVAPKTGGVPTQDPAPQEETGGVSALPKAQDDSEDEIPLLVPLKETPAAGSTKIQKAAIGKKSPKKSPGPNTARAKKRKASPALETPIAAEPKTPGKGPGKKARVKEEVEKERNSSLGKKDPRQTPKKPEAKFFTTASSSVKKAPRTLTQRPKKPKVPQST
What is the function of this protein?
Regulates cellular senescence through inhibition of PTEN translation.  Acts as a pro-apoptotic regulator in response to DNA damage.
What are the official names of this protein?
Ribosomal L1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family. Highly divergent.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: IF5A_METST
Sequence: MATKVAEIKTLKQGKYLVLGGEASKITSISTSSPGKHGAAKARIEAVGIFDNQKRSLVKPVNAKVDIPIIDKRVGQVLAIMGEEVQLMDLETYETIDLPIPEDLKGDIAEGKEVEYIEAMGNMKIMRTKGGN
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHEA_MYCBO
Sequence: MVRIAYLGPEGTFTEAALVRMVAAGLVPETGPDALQRMPVESAPAALAAVRDGGADYACVPIENSIDGSVLPTLDSLAIGVRLQVFAETTLDVTFSIVVKPGRNAADVRTLAAFPVAAAQVRQWLAAHLPAADLRPAYSNADAARQVADGLVDAAVTSPLAAARWGLAALADGVVDESNARTRFVLVGRPGPPPARTGADRTSAVLRIDNQPGALVAALAEFGIRGIDLTRIESRPTRTELGTYLFFVDCVGHIDDEAVAEALKAVHRRCADVRYLGSWPTGPAAGAQPPLVDEASRWLARLRAGKPEQTLVRPDDQGAQA
What are the official names of this protein?
Prephenate dehydratase, PDT.
Protein: PURK_VIBCH
Sequence: MRVLVLGAGQLARMMSLAGAPLNIETIAFDVGSENIVHPLTQTVLGHGLEQAIEQVDVITAEFEHIPHPILDLCARSGKLYPSAEAIKAGGDRRLEKALLDRAQVANARYTMIRSRDDLTSAIAEIGLPMVLKSALGGYDGKGQWRLKEPTQIESVWQELAQYLAANPEQAIVAEEFVAFDREVSLVGARNLVGDVVVYPLAENVHTQGVLSLSTAIDAPALQTQAKAMFKAVAEQLNYVGVLALEFFEVQGQLLVNEIAPRVHNSGHWTQQGAETCQFENHLRAVCGLPLGSTKLVRETAMINILGEDQLPAEVLALEGCHVHWYGKAKRSGRKMGHINVTADYSGELQRKLCQLATVLDEKAFPAVHAVAKEIQP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: KAT1_MOUSE
Sequence: MSKQLQARRLEGIDHNPWVEFTRLSKEYDVVNLGQGFPDFSPPDFAVQAFQQATTGNFMLNQYTSAFGYPPLTKILASFFGKLLGQEMDPLKNVLVTVGAYGALFTAFQALVDEGDEVIIIEPAFNCYEPMTMMAGGRPVFVSLRLSPAPKGQLGSSNDWQLDPTELASKFTPRTKILVLNTPNNPLGKVFSKKELELVAALCQQHDVLCFSDEVYQWLVYDGHQHISIASLPGMWERTLTIGSAGKSFSATGWKVGWVMGPDNIMKHLRTVHQNSIFHCPTQAQAAVAQCFEREQQHFGQPSSYFLQLPQAMGLNRDHMIQSLQSVGLKPLIPQGSYFLIADISDFKSSMPDLPGAMDEPYDTRFAKWMIKNKGLSAIPVSTFYSQPHHKDFDHYIRFCFVKDKATLQAMDKRLCSWKGEPQA
What is the function of this protein?
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA), an intermediate in the tryptophan catabolic pathway which is also a broad spectrum antagonist of the three ionotropic excitatory amino acid receptors among others.  Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites.  Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond.
What are the official names of this protein?
Kynurenine--oxoglutarate transaminase 1, Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, GTK, Glutamine--phenylpyruvate transaminase, Kynurenine aminotransferase 1, Kynurenine aminotransferase I, KATI, Kynurenine--oxoglutarate transaminase I.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: MURC_BRUC2
Sequence: MKMPLNIGLVHFIGIGGIGMSGIAEVLHNLGYKVQGSDQSDSANVQRLREKGIEVFVGHKAENLGDAEVIVVSTAIKKNNPELVAAREKLLPVVRRAEMLAELMRFRRAVAIGGTHGKTTTTSLVAALLDAGHLDPTVINGGIINAYGTNARMGDGDWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGNFDAVRAAFRQFVENVPFYGFGVMCLDHPEVQALVSRIEDRRIITYGSNPQAEVRFVNQRMDGAASLFDVVIRSRKGEATEIKDLRLPMPGLHNVSNATAAIAVAHELGISSDDIRRGLGSFGGVKRRFTHTGSWNGVEIFDDYGHHPVEIRAVLKAAREATSQAGGRVVAIVQPHRYTRLASLFDEFAACFNDADTVIVAPVYTAGEEPIEGVNSEELVSRIKTAGHRDARYATGPEALAPLVASIAQAGDFVVCLGAGNVTQWAYALPKELAEQGKK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_BORA1
Sequence: MNPTDLHPIKERMQAARAAAIADFRQHLRPDPLLSELRRIVDQALRDLLKLCPLPAGATLAAVGGYGRGELYPHSDVDLLILLPRAPDGPDESAIETLVASLWDLGLEPGHSVRTLAECETEASADITVETALLESRWLAGSRSLMKQFETAMTARLDARAFFRAKRVEMQQRHARYQDTPYALEPNSKESPGGLRDLQVILWMARAAGFGRNWRAVAQAGLLTAPEARDLRRAEQAFKRLRIELHLLTRRREDRLLFDLQPTLAEVYGIATTTTRRASELLMQRYYWAARLVTQLNVILIQNIEERLFPRPESDARAIDEEFRSLHGRLDIIREDCFERNPTLLLRAFLVMQQHPGLSGMSARTLRAIWHSRHRIDAQFRRNPVNRKLFLQILQQPRGIVHELRRMTMLNILPRYLPVFRRIVGQMQHDLFHVYTVDQHTLAVIRNLRRFTMPEHASEYPLASQVMAGLDRHWLLYVAALFHDIAKGRGGDHSELGARDARRFAQEHGLAPEDAELVEFLVRQHLLMSAVAQKRDLSDPEVINEFARQVKDERHLNALYLLTVADIRGTSPKVWNAWKGKLLEDLYRLTLAALGGAQDTRTVLAERKEEAARLLRLAGLRDDARDAFWQQLDVAYFLRHDASEIAWHTRHLYYQVQPDKPVVKVRPTEEGSGLQIMVYTRDTPDLFMNTCAYFDGKAFSIQDARIHTTRQGWALDSFIVLPAEPLADLRAQAALVEHELAERLRQAQGGARLADVRVFHRNRQSRVSRVFPVMPQAELHPDERSQSWRLSVTATDRPGLLHALARVMAENGVNLIMAKIMTLGDRVEDVFIISGAVLERPRTQMQFEHAVLDALAGE
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: OBG_PARD8
Sequence: MAESNFVDYVKIYCRSGKGGRGSSHFRREKYIPKGGPDGGDGGRGGHVYLRGNRNYWTLLHLKYERHIMATNGESGSAKRSSGKDGEDRVIEVPCGTVVYDAETGEFICDVTEDGQQVMLLKGGRGGLGNFNFKTATNQAPRYSQPGEPALERTVILQLKLLADVGLVGFPNAGKSTLLSVVSAAKPKIANYPFTTLEPNLGIVSYRDNRSFVMADIPGIIEGASEGKGLGLRFLRHIERNSLLLFMVPAEADDIKKEYEILHNELVKYNPELLDKRRVLAITKSDMLDEELIEALSQDLPEGIPYVFISSITGLGIVELKDLLWKELNKENFHEAERIVHKNIDVSTLEFEDDDEYIFPVDEDEDDPDEEYEEYWDDDEDEDTRK
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_ROSCS
Sequence: MDDAEILVDVQVVPQYAAVVDATLVERAVAQTLRTDDVAGPVEISILITDDADVHRLNQTYRGVDAPTDVLSFAEDDDHSFVRPPDAPRYLGDIAISWDRVVAQAAEYGHSRERELAFLVVHGVLHLLGYDHERGPVDEADMRAREEAILGALGLSREG
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_PECAS
Sequence: MIEADRLISADAVPEEEFLDRAMRPKLLKEYVGQPQVREQMEIFIQAARKRGDALDHLLIFGPPGLGKTTLANIVANEMGVNMRTTSGPVLEKAGDLAALLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYNVADLQYIVGRSAQCLGLDLTQEGSLEVARRARGTPRIANRLLRRVRDFSEVKSEGAITGTVATQALDMLAVDTEGFDYMDRKLLLAIIDKFMGGPVGLDNLAAAIGEERETIEDVLEPFLIQQGFIQRTPRGRMATQHAYRHFGLTREE
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.