PharMolix/UniProtQA huggingface dataset:
Protein: RS12_MOUSE
Sequence: MAEEGIAAGGVMDVNTALQEVLKTALIHDGLARGIREAAKALDKRQAHLCVLASNCDEPMYVKLVEALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFKCKK
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).  Subunit of the 40S ribosomal complex (By similarity).
What are the official names of this protein?
40S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS12 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAT_HV2RO
Sequence: METPLKAPESSLKSCNEPFSRTSEQDVATQELARQGEEILSQLYRPLETCNNSCYCKRCCYHCQMCFLNKGLGICYERKGRRRRTPKKTKTHPSPTPDKSISTRTGDSQPTKKQKKTVEATVETDTGPGR
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors.  Endosomal low pH allows Tat to cross the endosome membrane to enter the cytosol and eventually further translocate into the nucleus, thereby inducing severe cell dysfunctions ranging from cell activation to cell death.  Through (By similarity).
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus.
Protein: TRBC2_HUMAN
Sequence: DLKNVFPPKVAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGKEVHSGVSTDPQPLKEQPALNDSRYCLSSRLRVSATFWQNPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRADCGFTSESYQQGVLSATILYEILLGKATLYAVLVSALVLMAMVKRKDSRG
What is the function of this protein?
Constant region of T cell receptor (TR) beta chain (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn, ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor beta constant 2.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PDXB_SHESW
Sequence: MKILVDENMPFVEPLFGDLGEIIPVNGRTLTVAQVRDADVLLVRSVTKVNAELLSDNHQLKFVGSATIGTDHVDLAYLGERNIPFSNAPGCNATAVGEFAFIAMLELAQRFDSPLKGKVVGIVGAGNTGTATAKCLQAYGIKVLLNDPIKEKQGDPRSFVSLETIMAQADIISLHVPITRTGEHKTKHLLDEARLTALKPNTWLVNCCRGDVIDNKALVRVKRQRDDLRLVLDVWEGEPTPMPELVPLAEFATPHIAGYSLEGKARGTFMLYQKLCQLLNIAADKSLLDLLPSFNIKAVELATAPDEKALLQLARFVYDLRDDDNMFRNIFLNENGFDTMRKNHRHRREFSALALAYDRQLEVDWLSNLGFSGVGQ
What is the function of this protein?
Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate.
What are the official names of this protein?
Erythronate-4-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. PdxB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_BACSU
Sequence: MNKGQRHIKIREIITSNEIETQDELVDMLKQDGYKVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQRFNPLSKLKRALMDAFVKIDSASHMIVLKTMPGNAQAIGALMDNLDWDEMMGTICGDDTILIICRTPEDTEGVKNRLLELL
What is the function of this protein?
Represses the synthesis of biosynthetic enzymes and activates the arginine catabolism.  Controls the transcription of the two operons rocABC and rocDEF.
What are the official names of this protein?
Arginine repressor, Arginine hydroxamate resistance protein.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_PSECP
Sequence: MASLIEKLLRTGDKKTLRQLRNYADSINALEDSFKTFTDAELREETDRLRERHQDGEKLDNLLPEAFAAVREASSRTLGMRHFDVQLMGGAALHLGNIAEMKTGEGKTLVATAPAYLNALTGKGVHVVTVNDYLAEYQSDLMGRVYRFLGLTSGCILANQDPAVRREQYAADITYGTNNEFGFDYLRDNMAWDRNELVQRGHNFAIVDEVDSILIDEARTPLIISGPAQGDTNRWYSEFAKVVLRLQPEKDYEVDEKKRTVGVLEGGIEKVEDYLGISNLYESANTPLIGFLNNAIKAKELFKRDKDYVIMDGEVLIVDEHTGRILAGRRYNEGMHQAIEAKEGVEIKAENQTLATVTLQNYFRMYGKLSGMTGTAETEAAEFMSTYKLGVVAIPTNRDMQRIDQSDLVFKNETVKFDAVVRDIAERHEKGQPVLVGTTSVEKSEYLSRLLAKDGIRHEVLNAKNHAREAAIVAQAGRKAAVTVATNMAGRGTDIMLGGNAEFTAVAELAKRGLDPEENSEEYESAWPAALEAAKQAVKDEHEEVLNLGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLTDDLMRLFNSGAAERLMNSSVPDDVALESKLVSRAIASAQGQVEGRNAEQRKNVLKYDDVLNRQREAIYSDRRRILEGDDLHEKVQFFVEDTIMALIDDATAGGNGDDWDFHQLWTNLKTLYPVSVSADDIIEEAGGKSRLTVEFLKEELLSDARLVYQAREESIGSESMRELERRVVLSVIGRKWQEHLYEMDYLKEGIGLRAMAQRDPLVEYQREGFTLFQSMMEAIREESVGFLFNLEVEVTPAQDVVVEDAAGGHTEHVEPQVRAAGLEAPEKPAQLQYTAPSEGGGTQTRVETRSTGRSGNPAKAAEQDAAKDAAKRPAKKKRR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: SYW_TROW8
Sequence: MTSSAIRINKKPVVLSGIQPSSGMLHLGNYLGALKSFGRMQDDYTTYFMLANLHSMTFPQNPEVLRENTIRIAAQCIAAGIDPAKSIVFLQSDVYQHNQLAWVLGNVCTFGEAARMTQFKDKSGKQGNISTGLFTYPILMASDILLYDSAFVPVGADQKQHLELTRTLARRFNAQYGQTFLVPQPFECSIRIYDLQDPAVKMSKSSATESGTIFLLDSPDKIVKKIMRSVTDSEDVIGYDRETKPGVSNLVVMYSCLTDCTIEQTVNIYSGKKYSVLKKDLSDILVEVCTTIATRTNELLDDKNYIRKILVTASEQARGVAQKTIDRVYEKLGVY
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_XANOR
Sequence: MRIIFAGTPDFAVASLRAAAQRHEVVAVYTQPDRPAGRGRGLTPSPVKIEAIARGIAVFQPQTLRSPEALATLRSLNADLMVVVAYGLILPNAVLAVPTHGCWNVHASLLPRWRGAAPIQRAIEAGDTETGVCLMQMEAGLDIGPVLLSQRIEIGEQETGGQLHDRLAALGAQVLSDGLGLLRAGIRPVAQPQPAEGVTYAHKLDKAQARLDWAQPAQELARRVRAFNPWPVAEAILAGERVRLHGAVALELAHQQPPGSLLAASKQGIDIACGQGALRVRVLQREGGKAITAADYLNARRDLLALR
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: HXT5_YEAST
Sequence: MSELENAHQGPLEGSATVSTNSNSYNEKSGNSTAPGTAGYNDNLAQAKPVSSYISHEGPPKDELEELQKEVDKQLEKKSKSDLLFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGCAIGGIVLSKLGDMYGRKIGLMTVVVIYSIGIIIQIASIDKWYQYFIGRIISGLGVGGITVLAPMLISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSIFMIVGMTFVPESPRYLVEVGKIEEAKRSLARANKTTEDSPLVTLEMENYQSSIEAERLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGLEDSFETAIVLGVVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFTPFITSAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNEMYEENVLPWKSTKWIPPSRRTTDYDLDATRNDPRPFYKRMFTKEK
What is the function of this protein?
Probable glucose transporter.
What are the official names of this protein?
Probable glucose transporter HXT5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y265_SODGM
Sequence: MKRTKQINHASFRKHWRAYRMAPVALAVGAVFVLAGCEKSDENVSLYMNSDDCARANPSLSEQCTTAYNAAQQEAVKTAPKYASRADCVAEFGEEQCTQVPAQAGMAAESQHSGSMWMPLMAGYMMGRMMVGGYSQQPLFTSLAANSPARGQFVDARGRNYGASTSGRSMTVPKTALAPKPATTQTITRGGFGETVAKQNALRSSSATPHRTMGG
What are the official names of this protein?
UPF0441 protein SG0265.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: HRCA_ACHLA
Sequence: MISSRQKLILKAIIDMYSEKGEPVGSKALMALPYLNYSSATLRYDMAVLEELGFLEKMHTSSGRVPSERGYRYYIEHLVTRDNDVTEVFPLIDEVFSKKALGREHTIKEALKLLTDLTSYTAVAVGPDILQSHIKRIEMVPLGLKDAVMLIVTDTGHVQHQQIHISDDMRMDDIKEVIHTLDDLLKNRTLEDALKVLKEEYAISELNQFMSYQSQIIDSFIEAFSKFASDSFYLSGMTNAFEQPEFNDVSHMKRFIDMMDRREIVKLIGTAEGISVRFGSDMEIKPLNQMTIISIPYQIDSKQKGTIALVGPSRMSYQKVIPLLEYIAANLAKLYKDNNKET
What is the function of this protein?
Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons).  Prevents heat-shock induction of these operons.
What are the official names of this protein?
Heat-inducible transcription repressor HrcA.
What is the protein family that this protein belongs to?
Belongs to the HrcA family.
Protein: MLEC_MOUSE
Sequence: MLRPRGAEGTAVALLRLLLLLLLLGPKLRGPGLGVVGAAGAGLPESVIWAVNAGGEAHVDVHGIHFRKDPLEGRVGRASDYGMKLPILRSTPEDQILYQTERYNEETFGYEVPVKEEGDYVLVLKFAEVYFAQSQQKVFDVRLNGHVVVKDLDIFDRVGHSTAHDEIIPMSIRKGKLSVRGEVSTFTGKLYIEFVKGYYDNPKVCALYILAGTVDDVPKLQPHPGLEKKEEEEEEEEYDEGSNLKRQTNKNRVQSGPRTPNPYASDNSSLMFPILVAFGVFIPTLFCLCRL
What is the function of this protein?
Carbohydrate-binding protein with a strong ligand preference for Glc2-N-glycan.  May play a role in the early steps of protein N-glycosylation (By similarity).
What are the official names of this protein?
Malectin.
What is the protein family that this protein belongs to?
Belongs to the malectin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RL332_STAAS
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: CCMA_XANOR
Sequence: MIEPLHTAPPLLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVEHGQIQIDGKTAKRGDRSRFMAYLGHLPGLKADLSTLENLHFLCGLHGRRAKQMPGSALAIVGLAGYEDALVRQLSAGQRKRLALARLWLSPAPLWLLDEPYANLDLDGITLVNRMISAHLRGGGAALVTTHGAYAAPPVRTRMLTLEAAA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SERC_COXB1
Sequence: MSRVYNFSAGPAAIPEEVLFTVRDELLDWHGIGMSIAEVSHRGEEFIGVAEEAERDLRELLAVPESYHILFLQGGSRLQFAMVPMNLLANHKKAVYIDSGVWSNLAIREAKNYCDPHLATNAKELNYTGIPDQATWDMPNEAAYFYYVDNETVNGIEFPFIPDTHLTLVCDMSSNLLSRPFDVSRYGLIFACAQKNMGLAGLTIVIVHDDLLKRSPLPTTPSYLQYALHAKERSFINTPPTFAWYLAGLIFKWVKNQGGVAVLAERNQRKAAKLYKFIDKSNFFDNPINPTYRSRMNVIFRLADERLNSLFLKEATENGLANLKGHRLLGGMRASIYNAMTEEGVDALINFMGQFEKRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATSE_STAAC
Sequence: MFSKVNNQKMLEDCFYIRKKVFVEEQGVPEESEIDEYESESIHLIGYDNGQPVATARIRPINETTVKIERVAVMKSHRGQGMGRMLMQAVESLAKDEGFYVATMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIEMTKKLTSLN
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl coenzyme A (AcCoA) to an acceptor substrate and releases both CoA and the acetylated product.  It displays the highest activity for L-threonine.  It can also use L-tryptophan, and to a much lesser extent L-tyrosine.
What are the official names of this protein?
Acetyltransferase SACOL1063, GCN5-related N-acetyltransferase, GNAT.
What is the protein family that this protein belongs to?
Belongs to the UPF0039 (ElaA) family.
Protein: SYR_CHLPD
Sequence: MHDFFLPVIKNALLSLAVSSDKPVLIERPADKKFGDFSTNIAFLIAKESRRNPKEFAGELIAHLSFPPDTIKSMTVAGPGFINFFLTPTFIMQSVEQILLEGKGYGRSCLGKGKKAIVEYVSANPTGPLTIGRGRGGVLGDCIANLLETQSYAVTREYYFNDAGRQMQILGESVRFRYLELCGVAETFPETHYQGAYIREIAESLFAGHGAALQGVHDLLPFIKSAETIIFKSIKNTLERIGIRHDSFFNEHTLYHREGSGQSANEEVIDLLREKQFIGEYDGATWFLTSRIGQEKDKVLIKSSGEPSYRLPDIAYHITKFKRGYDLMVNVFGADHIDEYPDVLEALKILGYDASRIQVAINQFVTTTVDGQSVKMSTRKGNADLLDDLVDDVGPDATRLFFIMRSKDSHLNFDIDLAKKQSKDNPVFYLHYAHARICSLLRMAALENGFDPDGSGHHLLQLLDSEPELRLGLLLLEYPQMITASIRLLEPQKMVDYLHSVAELYHKFYQECPILKAEPDISKARLFLSLATKQVLCNGFRILGISAPESM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA12_BOVIN
Sequence: MRALLLLGALLVSLESTVSTPPWKGPKKHKLTDSEHTVVLTVTGEPCHFPFQYHRQLHHKCIHRGRPGPRPWCATTPNFEKDQRWAYCLEPKKVKDHCSKHNPCQKGGTCVNMPDGPRCICADHFTGKHCQKEKCFEPQFFRFFHENEIWHRLEPAGVVKCQCKGPNAQCKPLASQVCRTNPCLNGGSCLQAEGHRLCRCAPSFAGRLCDVDLKASCYDDRDRGLSYRGMAGTTLSGAPCQSWASEATYWNVTAEQVLNWGLGDHAFCRASTPPRGYRNPDNDTRPLCFIWKGDRLSWNYCRLAPCQAAAGHEHFPLPSPSALQKPESTTQTPLPSLTSGWCSPTPLASGGPGGCGQRLRKWLSSLNRVVGGLVALPGAHPYIAALYWDQHFCAGSLIAPCWVLTAAHCLQNRPAPKELTVVLGQDRHNQSCEQCQTLAVRDYRLHEAFSPITYQHDLALVRLQESADGCCAHPSPFVQPVCLPSTAARPAESEAAVCEVAGWGHQFEGGEYSSFLQEAQVPLIDPQRCSAPDVHGAAFTQGMLCAGFLEGGTDACQGDSGGPLVCEDETPERQLILRGIVSWGSGCGNRLKPGVYTDVANYLAWIREHTAS
What is the function of this protein?
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin.  Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa.  Alpha-factor XIIa activates factor XI to factor XIa (By similarity).
What are the official names of this protein?
Coagulation factor XII, Hageman factor, HAF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEM1_ACTP7
Sequence: MTILALGINHKTASVNLRSKVAFDDQKRQLAFEQIQHRALAESVVILSTCNRTELYFHNAEITPREEHEDNIAWREQCFEWFAEIHQLEHNELRECIYFKQNMEAARHLMRVACGLDSLILGEPQILGQVKQAYQYSENFYQSQNSHISTKLSRLFQRTFSTAKRVRSETEIGSSAVSVAYAACGLARQIFDNFGKLRFLLVGAGETIELVARYLIQHGAKNIMIANRTPQRAETLAERLNTPMQILSLSALQIGLNQADIVISSTGSPDMLISKEMVEIAQKQRQFDPMLLIDIAVPRDIDENAGELDAVYSYSVDDLQHIIQRNMAQREQAAEQAAQIVDEECKAFFEWLKQQQSSDLIKRYRQDAEQTRQELLAKALVALTSGQDSEKVLNELSYKLTNSLLHVPTQALQAMAKSGNSQGLQSFSKALKLEEQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RS1_BUCBP
Sequence: MTESFAQLFEESLKNIKTRPGSIIQGTVVAITKDTILVDAKLKSESKIPIDQFKNSQGELEVKVGDQIDVALDAIEDGFGETLLSREKAKRHEAWLTLEQAYKDSKTVVGLINGKVKGGFTVELEDIRAFLPGSLVDIRPVRETMHLEGKELEFKVIKLDQKRNNVVVSRRAVIESEYNAERNLLLETLQEGLIVSGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNIGDEVKIKILKFDREKIRVSLGLKQLSDDPWTKISERYPEKTKITGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKMVQVNSVVKVMILDIDEERRRISLGLKQCKNNPWMEFSKKYNKGSHVVGKIKSITDFGIFIGLEGSIDGLVHLSDISWNISGEESVKKYKKGEEVLAVVLQVDPDRERISLGIKQLQEDPFAKYVSSHKKGSLVSGTIKKIDNNVIVVSLSEHIDGLIKFLNISDEIMNVHDNKPWNKAKIGEIVEVKLNSIDKKERIIYLSILEKQELKISNDIKKNNSHKQEIDKDKNFSNAMTEAFKAAKNVD
What is the function of this protein?
Binds mRNA; thus facilitating recognition of the initiation point.  It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity).
What are the official names of this protein?
30S ribosomal protein S1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS1 family.
Protein: NDUF2_MOUSE
Sequence: MSWWSGVWRSVWSALSREVREHVGTDHLGNKYYYVAEYKNWRGQTIREKRIVEAANRKEVDYEAGDIPTEWEAWIRRTRKTPPTMEEILKNEKYREEIKIKSQDFYEKDKLGKETSEELLPSPTATQVKGHASAPYFGREEPSVAPTSTGKTFQPGSWTPEDGKRQSQ
What is the function of this protein?
Acts as a molecular chaperone for mitochondrial complex I assembly.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2, Mimitin, Myc-induced mitochondrial protein, MMTN, NDUFA12-like protein.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA12 subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: LLDD_CROS8
Sequence: MIISAASDYRAAAQRILPPFLFHYIDGGAYAEYTLKRNVEDLSQVALRQRVLKNMSDLSLETTLFNETLSMPVALGPVGLCGMYARRGEVQAARAASAKGIPFTLSTVSVCPIEEVAPVMNRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGTNAAMRRYWQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDITILADSGIRNGLDVVRMIALGADSVLLGRAYLYALATHGEKGVANLLNLIEKEMRVAMTLTGAKSIKEITRESLVPSPEFTSVLADLPAASAKPKQDDAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RK14_CHLAT
Sequence: MIQSQTYLNVADNSGARKIMCIRVLGGSQRQYATIGDVIIAVVKDSVPNMALKRSEVVRAVVVRTRKGLRRDNGMTIRFDDNAAVVINKEGNPRGTRVFGPVARELRDRNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KS6A4_MOUSE
Sequence: MGDEDEDEGCAVELQITEANLTGHEEKVSVENFALLKVLGTGAYGKVFLVRKTGGHDAGKLYAMKVLRKAALVQRAKTQEHTRTERSVLELVRQAPFLVTLHYAFQTDAKLHLILDYVSGGEMFTHLYQRQYFKEAEVRVYGGEIVLALEHLHKLGIIYRDLKLENVLLDSEGHIVLTDFGLSKEFLTEEKERTFSFCGTIEYMAPEIIRSKAGHGKAVDWWSLGILLFELLTGASPFTLEGERNTQAEVSRRILKCSPPFPLRIGPVAQDLLQRLLCKDPKKRLGAGPQGAQEVKSHPFFQGLDWVALAARKIPAPFRPQIRSELDVGNFAEEFTRLEPVYSPAGSPPPGDPRIFQGYSFVAPSILFDHNNAVMADVLQAPGAGYRPGRAAVARSAMMQDSPFFQQYELDLREPALGQGSFSVCRRCRQRQSGQEFAVKILSRRLEENTQREVAALRLCQSHPNVVNLHEVLHDQLHTYLVLELLRGGELLEHIRKKRLFSESEASQILRSLVSAVSFMHEEAGVVHRDLKPENILYADDTPGAPVKIIDFGFARLRPQSPAEPMQTPCFTLQYAAPELLAQQGYDESCDLWSLGVILYMMLSGQVPFQGASGQGGQSQAAEIMCKIREGRFSLDGEAWQGVSEEAKELVRGLLTVDPAKRLKLEGLRSSSWLQDGSARSSPPLRTPDVLESSGPAVRSGLNATFMAFNRGKREGFFLKSVENAPLAKRRKQKLRSAAASRRGSPVPASSGRLPASAAKGTTRRANGPLSPS
What is the function of this protein?
Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes.  Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin.  Plays an essential role in the control of RELA transcriptional activity in response to TNF.  Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and EGF, which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN.  May also phosphorylate 'Ser-28' of histone H3.  Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 1 (HMGN1/HMG14).  In lipopolysaccharide-stimulated primary macrophages, acts downstream of the Toll-like receptor TLR4 to limit the production of pro-inflammatory cytokines.  Functions probably by inducing transcription of the MAP kinase phosphatase DUSP1 and the anti-inflammatory cytokine interleukin 10 (IL10), via CREB1 and ATF1 transcription factors (By similarity).
What are the official names of this protein?
Ribosomal protein S6 kinase alpha-4, S6K-alpha-4, 90 kDa ribosomal protein S6 kinase 4, Nuclear mitogen- and stress-activated protein kinase 2, RSK-like protein kinase, RLSK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROA_MYCPA
Sequence: MGLQAPFRSGGGTSRPQGRAAPRAVDLRREVHDAARRARVASRVLALLPAVAKDQALRSAADAIAGHAELILSANAEDLETARAAGTPSAMLDRLALDTKRVEGIAAGLRQVAGLPDPVGEVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNVTVDAFGLALKSGNAVLLRGSSSATRSNQALVQVLRASLVSEDLPADAVQLLSADDRATVTHLIQARGLVDVVIPRGGANLINAVVRDAQVPTIETGVGNCHVYVHEGADLEVAERVLLNSKTRRPSVCNAAETLLVDAAIAEEALPRLVTALQDAGVTVHGGFARDATEDDLRREYLSMDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNMAAAQRFTDGVDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIAWGDGQTRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.