PharMolix/UniProtQA huggingface dataset:
Protein: GUN1_ACRSP
Sequence: WLSGVDKIRGVNLGSAFIIE
What is the function of this protein?
Endo-1,6-beta-glucanase that has highest activity against the beta-1,6-glucan pustulan.  Also active against the beta-1,6-glucan lutean.  Lower activity against laminarin (beta-1,3-glucan with beta-1,6-branches).  Little or no activity against gentiobiose, yeast glucan, lichenin, scleroglucan, curdlan, barley glucan, CM cellulose, HE cellulose, pachyman and pullulan.
What are the official names of this protein?
Endo-1,6-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: AROA_BUCA5
Sequence: MQNSLDLKPISHVNGTVCLPGSKSISNRVLLLSSIAKGTTCLTNLLNSHDTQHMLNALKKLGVRYNLSDDKKTCHVQGIGGPFHLSEAISLYLGNAGTAIRPLLSVLSLHKNNILLNGDDRMHERPIGDLVDALIQGGAVIEYKKNKGYPPICTKGGFLGGSIFLNGNISSQFLTSLLISTPLALKDTTIFIKGNLVSKPYIDITLNLIKIFGVNIEHDSYNVFYIKGKQQYKTPGKYTIEGDASSASYFLAAAAIKGGSIKVTGVGKKSIQGDIEFANILEKMGATIFWEDYSITCTRNKLNAIDLDMNHIPDAAMTVAILALFSKGTTIIRNIYNWRVKETDRLSAMTIELRKIGAIVEEGRDFLSISPPIFFQYSSIETYNDHRMAMCFSLISLSGVGVNILNPNCISKTFPSYFKDFLSISKI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDHN_PARMW
Sequence: MPLLLTGRTFRRDLEAHGCLAVHAPLEGGAETRLLRRLRGAGYRTRLWSARGLGDPEVFLTQKHGIRPPHLGHQSVGRGAAVGEVQEVVPQLGDLLDGDAQVALWLLEGQVLSQSELRSLCDLCSREPRLRIIVEMGGARSLRWQPMSGLLAS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HOLE_ECOLI
Sequence: MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSWFRERLIAHRLASVNLSRLPYEPKLK
What is the function of this protein?
The exact function of the theta subunit is unknown.
What are the official names of this protein?
DNA polymerase III subunit theta.
Protein: RS17_LEIXX
Sequence: MAETTKATAAEPAADEALVRGYRKARRGYVVSDKMDKTIVVEVEDRVKHPLYGKVLRRTSKVKAHDESNVAGIGDLVLINETRPLSASKRWRLVEILEKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RL31B_LEIXX
Sequence: MKTGIHPDYAPVVFRDLASGATFLTRSTVSSQKTIEWEDGSTYPVIDVEISSESHPFYTGKQRILDSAGRVEKFNTRYKNFGK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: CIP4_DANRE
Sequence: MDWGTELWDQYDILDKHTQSGLDLVDKYMKFVKERTDIEQNYAKQLRNLTKKYSPKRGSKEEQECRFSNHQAFLDILNEMNDYAGQRELIAENMMINICVELNKYLQELKQERKMHLSEAKKSQQSLEAMYKQLDNSKKRFEREWREAEKAAQYADKTDQDLNATKADVEKAKQQAHLRTHIAEDCKNDYAAQLQKYNKGQSQFYFTDMPQIFNKLQDMDERRIKKMAQGYILFADTERHVMPIIGKCLEGMTRAGTNVNARNDSMVLIEQHKSGFERPGDLDFEDYSQGINRASSDSSLGTPKGPLELLGKNKNKTFRLFNKKSKFTPEKPVDTEGFTHLPPEQRRKRLQQKIDDMSKELQKEMDQSEALGKMKDVYEKNPQMGDPASLAPQIGQTAQNMDRLRGELNKYESWLAEAGGRGDSIRYSTHSINNNGAHNPNSHDGSCTLFSPGALSDETDPSQAIYTEFDDEFEEEELATPIGQCTALYNFPGSSEGTISMQEGEVLAVVEEDKGDGWTRVRRNNGDEGYIPTSYATITLNK
What is the function of this protein?
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis.
What are the official names of this protein?
Cdc42-interacting protein 4 homolog, Thyroid receptor-interacting protein 10 homolog.
What is the protein family that this protein belongs to?
Belongs to the FNBP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Lysosome. Cell membrane.
Protein: CEMA_LOLPR
Sequence: MKKKKALPSLLYLVFIVLLPWGVSFSFNKCLELWIKNWWNTRQSETLLPYIQEKRILERFIELEELSLLDEMIKEKLKTHAQKPPIGIHKEIIQLVKMDNEDHLHIILHFSTNIICLAILSGFFFLSKEELVILNSWVQEFFYNLNDSIKAFFILLVTDFFVGFHSTRGWELVIRWVYNDLGWAPNELIFTIFVCSFPVILDTCLKFWVFFCLNRLSPSLVVIYHSISEA
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: QUEF_NEIG2
Sequence: MSRNNEELQGISLLGNQKTQYPTGYAPEILEAFDNKHPDNDYFVKFVCPEFTSLCPMTGQPDFATIVIRYIPHIKMVESKSLKLYLFSFRNHGDFHEDCVNIIMKDLIALMDPKYIEVFGEFTPRGGIAVHPFANYGKAGTEFEALARKRLFEHDAQ
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AT221_PENRW
Sequence: MSIQENVESPQYPGDDTRPTSKRELAGWYCYGWAAEVFVVCAMGSFLPITLEQMARDRGVLLSDKTTPCSATWRPPLPPPGSDAPVYLPQVSDGGQCIIYFLGAEINTASFALYTFSLSVLVQAVIIISMSGAADHGTYRKKLLIVFAFIGSIATMLFLVVVPKVYLLGGLLAIISNTCFGASFVLLNSFLPVLVRHHPSLKESEEVASPDDNVTGPRGDPLFSSTGDIDRTNVDDSTPLLGPNREAGKTSAATITSLELRLSTRISSYGIGIGYIGAVILQVISILVVVVVRPPTFSLRLVLFLIGLWWFVFTIPASLWLRTRPGPPLLDSGGKPLHSWTGYMVYAWKSLGKTVTRARQLKDIVIFLAAWFLLSDGIATVSGTAVLFAKTQLNMKPAALGLINVIVMLAGVFGAFSWSYISNFFNLRASQTIIACIILFELIPLYGLLGFIPAVQRVGLGLHQPWEMYPLGALYGLVMGGLSSYCRSFFGQLIPPGYEAAFYALYAITDKGSSIFGPAIVGAITDRYGEIRPAFVFLAVLIFVPLPLMLLVDVDRGKRDAVALGAELDGIPQGSEYGAISDDQTTEDPIEE
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-1.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: TOP1_YEAST
Sequence: MTIADASKVNHELSSDDDDDVPLSQTLKKRKVASMNSASLQDEAEPYDSDEAISKISKKKTKKIKTEPVQSSSLPSPPAKKSATSKPKKIKKEDGDVKVKTTKKEEQENEKKKREEEEEEDKKAKEEEEEYKWWEKENEDDTIKWVTLKHNGVIFPPPYQPLPSHIKLYYDGKPVDLPPQAEEVAGFFAALLESDHAKNPVFQKNFFNDFLQVLKESGGPLNGIEIKEFSRCDFTKMFDYFQLQKEQKKQLTSQEKKQIRLEREKFEEDYKFCELDGRREQVGNFKVEPPDLFRGRGAHPKTGKLKRRVNPEDIVLNLSKDAPVPPAPEGHKWGEIRHDNTVQWLAMWRENIFNSFKYVRLAANSSLKGQSDYKKFEKARQLKSYIDAIRRDYTRNLKSKVMLERQKAVAIYLIDVFALRAGGEKSEDEADTVGCCSLRYEHVTLKPPNTVIFDFLGKDSIRFYQEVEVDKQVFKNLTIFKRPPKQPGHQLFDRLDPSILNKYLQNYMPGLTAKVFRTYNASKTMQDQLDLIPNKGSVAEKILKYNAANRTVAILCNHQRTVTKGHAQTVEKANNRIQELEWQKIRCKRAILQLDKDLLKKEPKYFEEIDDLTKEDEATIHKRIIDREIEKYQRKFVRENDKRKFEKEELLPESQLKEWLEKVDEKKQEFEKELKTGEVELKSSWNSVEKIKAQVEKLEQRIQTSSIQLKDKEENSQVSLGTSKINYIDPRLSVVFCKKYDVPIEKIFTKTLREKFKWAIESVDENWRF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity).
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I, Maintenance of killer protein 1.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumoylated forms found in both nucleoplasm and nucleoli (By similarity).
Protein: RNH2_SHIB3
Sequence: MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_MYCS2
Sequence: MSKNSKAYREAAEKVDRTKLYTPLEAAKLAKETSSKKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGEKAEQAQAAGADIVGSDDLIEKIQGGFLDFDAAIATPDQMAKVGRIARVLGPRGLMPNPKTGTVTPDVAKAVQDIKGGKINFRVDKQANLHFIIGKASFDETKLAENYGAALDEVLRAKPSSSKGRYLKKVTVSTTTGPGIPVDPSVTRNFTEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: TRMB_STRP4
Sequence: MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVEVGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTDYFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: THEM5_MOUSE
Sequence: MLRTSFQGVARLVRHKALYRSPCLLPRVHLASAFGSSTESLVARFCPEKTDLKDYALPNASWCSDMLSLYQEFLEKTKSGGWIKLPSFKSNRDHIQGLKLPFGLETASDKQDWRLFTRSIQLEGQGYEYVIFFHPSEKKSVCLFQPGPYLEGAPGFAHGGSLAALMDETYSKTAYLAGEGLFTLSLNIKFKNLIPVGSLAVLDIQVEKIEDQKLYMSCIAQSRDKQTVYAKSSGVFLQLQLEEQSQEQ
What is the function of this protein?
Has acyl-CoA thioesterase activity towards long-chain (C16 and C18) fatty acyl-CoA substrates, with a preference for linoleoyl-CoA and other unsaturated long-chain fatty acid-CoA esters (By similarity).  Plays an important role in mitochondrial fatty acid metabolism, and in remodeling of the mitochondrial lipid cardiolipin (PubMed:22586271).  Required for normal mitochondrial function (PubMed:22586271).
What are the official names of this protein?
Acyl-coenzyme A thioesterase THEM5, Acyl-CoA thioesterase THEM5, Acyl-coenzyme A thioesterase 15, Thioesterase superfamily member 5.
What is the protein family that this protein belongs to?
Belongs to the THEM4/THEM5 thioesterase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: B4GT1_RAT
Sequence: PGATLQXAXXLLVAVXAXPPPPLGVXPKPXPG
What is the function of this protein?
This protein is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
What are the official names of this protein?
Beta-1,4-galactosyltransferase 1, Beta-1,4-GalTase 1, Beta4Gal-T1, b4Gal-T1, Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase, Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase, Lactose synthase A protein, N-acetyllactosamine synthase, Nal synthase, Neolactotriaosylceramide beta-1,4-galactosyltransferase, UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1, UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 7 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Cell membrane; Single-pass type II membrane protein. Cell projection, filopodium. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Protein: ATGT_METHJ
Sequence: MTLSFEILEKDIAGRIGKLSGQGKIVKTPTLLPVINPHLNLIPPKEMQEMGVEAVITNAYIFSRSEEYRERALTDGLAKTLDFDGVIMTDSGSFQLSVYGEVEITNAQTIAFQQAIKSDIIVPLDIPTHPDSPREQVEQELSVTMDRIMEAKDIADHEHHTLAGPVQGGLFPDLREETGRRLSEAGFRFCPIGAVVPLMESYRYAELVKVVMAAKRGLSPAVCVHLFGAGHPSMFALAVAMGCDLFDSAAYALYAKDGRYMTTHGSYHLNELSYLPCPCPVCVGHTAKELNESPDRERLLAMHNLRVSLAEINRVRQAIRDGVLWELVDERCRSHPALLRGYRTLLGYNEELTALDRETKRRFFYRGDESCKRTEVVRYHQMVGRLTAGERTLISFSRHIKKKQTEEYDSVFYFKPPFGPFPAELTETFPIGQSEIPDFDEEMIKTGCIGIARLMETNPDSHFTIRCRPVWKDLITQILPTVEVQDEGS
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: ASIP_BOVIN
Sequence: MDVSRLLLATLLVCLCFLTAYSHLAPEEKPRDERNLKNNSSMNLLDFPSVSIVALNKKSKKISRNEAEKKKRPSKRKAPMKNVARTRPPPPTPCVATRDSCKPPAPACCDPCAFCQCRFFRSACSCRVLNPTC
What is the function of this protein?
Involved in the regulation of melanogenesis.  The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity).
What are the official names of this protein?
Agouti-signaling protein, ASP, Agouti switch protein.
What are the subcellular locations of this protein?
Secreted.
Protein: CLHC1_RAT
Sequence: MPTQEVKKHAVLPPIISRNDKEFLESMQRYIITETKRVGCNEEGPPDEYYTIYRNVFDKVIDYVNAYKSVLTSIKKEYDAFIETVKKGRRNAFYLHGKLKVLAAEPTALVYHQRRTIQLEAKMRIIDNNSKAIQLQIDQMKQLRMEYENTEVKLCASSKQLWKPIPGMTLQDSVNLDALNNHKQNLEDKCRKLKQDMSTMYVSAQKKADLDEEMIVLLKRRDIAENLNKDLRFRHQRLQVISHTLNSWMKQNMRIPFKDVLERIQQTKAIYGHAKVVDELFEDDPNKTKEAIVMLYYIERFHELISLGEYEKAACFAANSPKRILQNAGTMNKFKAIGKVRGKPLPLLLFFEAIFNTSQAFKRAINVDLTLEGIKCGLSEERLDLVTHWVTQAKLTFSEKVGDAICAYGEQHPYHKSKCLALAQIVYNECGLHKKAILCLCRQGQFHEAMEHIQQSKDINTDDLIQLITACPQIDLIRGLTEERNGKPPFLSFGLTVLHLFSVDMKKIGMKLLQEVSKAEKDVIEHLVMSDLFCSIEKWQELANICLQNGFKNLSNDIMSILRSQAGVSEISEDDTTNVMEHVFW
What are the official names of this protein?
Clathrin heavy chain linker domain-containing protein 1.
Protein: LEPA_POLNA
Sequence: MNHIRNFSIIAHIDHGKSTLADRLIQRCGGLQDREMSAQVLDSMDIEKERGITIKAQTASLKYKALDGQVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTALDLGVTVVPVLNKMDLPQADPDNAKQEIEEVIGIDATDAIPCSAKTGMGIDEILEAVVALIPAPKGNPDAALRAMIIDSWYDAYVGVVMLVRVVDGRLAKGDRIKLMASEATYNAEQLGVFTPHTEARQALEAGEVGFVIAGIKELQAARVGDTVTLIKGGTGGAAFTATEALPGFKEIQPQVFAGLYPSEASEYESLRDALEKLKLNDASLHYEPEVSEALGFGFRCGFLGLLHMEIVQERLEREFDQDLITTAPSVVYEVLKADGTTIKVENPSKIPDAGRVNEIREPIVTVHLYMPQDYVGAVMTLANQKRGVQLNMAYHGKQVMLTYEMPLGEIVLDFFDKLKSVSRGYASMDYEFKEFRASDVVKVDILLNGEKVDALSIIVHRSQSAYRGRAVVAKMREIISRQQFDVAIQAAIGANIIARETIKALRKNVIAKCYGGDISRKKKLLEKQKAGKKRMKQIGSVEVPQEAFLAILQVED
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DBP10_EMENI
Sequence: MPSRAASPALSENEFDITGALFQNDSDSDAETQKPTKRKKVPAAPNVNLDFLGEANAGDSDEDDEAFIAEKQTSANRKSANLKGRTVKKGGGFQAMGLNANLLKAIARKGFSVPTPIQRKTIPVIMEDQDVVGMARTGSGKTAAFVIPMIEKLKSHSTKFGARGLILSPSRELALQTLKVVKELGKGTDLKSVLLVGGDSLEEQFGMMAGNPDIVIATPGRFLHLKVEMNLDLSSIKYVVFDEADRLFEMGFAAQLTEILHGLPSTRQTLLFSATLPKSLVEFARAGLQDPTLVRLDTESKISPDLQNAFFSVKSAEKEGALLYILNEVIKMPTGPTEASLRLKEKGPEDSKNKKRKRAEMERAVNMKESPTKHSTIVFAATKHHVDYLYSLLREAGFAVSYVYGSLDQTARKIQVQNFRTGISNILVVTDVAARGIDIPILANVINYDFPSQPKIFVHRVGRTARAGRKGWSYSLVRDADAPYLLDLQLFLGRKLVLGRESDQVNFAEDVAVGSLPRDGLSQTCEWVSRVLDDDADIFAQRAVSTKGEKLYLRTRNAASAESAKRAKQVVTSDNWTAVHPLFQDEASNLEAEREKMLARIGGYRPQETIFEVQNRRGGKGGKASEPDEALDSIKRVRSTLEAKKKQRAQAEELEATTNTDGAEVDGDAFSDLEGDNANIPDNMSLASESDLEVTFSSYNTTDKASKSNSNSKSDSTPTTLFQNPEYFMSYTPANTSLAEDRAYGVHSGTNANFASATRNATMDLQADEGGKGFGEPRTLMRWDKRHKKYVSRQNDEDGSKGTKLVRGESGAKIAATFRSGRFDAWKKGKRVGRLPRVGEAETPGLAADLGGSGGSFGGKRFRHKSEKAPKAADPLRGDYEKMKKKAEAARERAASKVGGVTSGGKSEIRNTDDIRKARKLKQKRREKNARPSRKK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SUB11_TRIVH
Sequence: MGLFKVIFTAVAALSAVDAAELLSSAKSKDIIPNSYLVVMKDSVSSAELDSHVSWVTDLHREGVAKRGAENLGGFKHSYKINGWHAYSGSFDSETLASILDNDKVDFVEHDRHVYISGFVTQKDAPSWGLGRVSHRMNGTRDYVYDESAGSGITFYGVDTGIDIHHPDFGGRAVWGINVVNDTKDNDRHGHGTHTAATAAGTKYGLAKKANVVAVKALNDYGAGLWSNIMKALEWCVNDAREKKILGKAVLNLSISGGKVVAANQAITNAAKAGIFVSVAAGNDNQDATNKSPASAENVCCAAATTIRDDKAKFSNYGSVVKLYAPGQGITSATPNNQTGVMSGTSMAAPHVGGVGATLMASKGIAPAAVCAELIKMASGPVLNPGANTTNKLLYNRSGK
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 11.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PUR7_ACAM1
Sequence: MSTGEFLYEGKAKIIYRTDDPDILLAQYKDDATAFNAQKRGTITNKGRINCAIATHLFKVLEAAGIATHFIDQPNPDQMRMRAVQIVPLEVVVRNIAAGSLCQQTGLALGVPLSQPLVDFYYKDDALGDPLLTRDRIFLLELTTPEQLEQLRQLALRINQILINFFHQCGITLVDFKLEFGMTSDQQLLLADEISPDTCRLWDDAESDPTRRVMDKDRFRRDLGEVDTAYARVMERVLAQDIYVP
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: METN_CUPNH
Sequence: MIELQGLSQRFPGASGDVHALRDVSLSIAAGEVFGIIGRSGAGKSTLVRAINLLNRPSSGRVIVAGQELTALDTGALRLARREIGMIFQHFNLLSSRTVYENVALPLELAGKPKAEIAATVLPLLDLVGLSALKGRYPAQISGGQKQRVGIARALASKPKVLLSDEATSALDPETTRSILELLKQINRDLGLTIVMITHQMEVIKQVCDRVAVLEAGRVVETGRVIDVFLRPQHDVTRAMIGDVISQELPASVLKRVESRLGNGRDHVYRLAFTGEGVDQPVLAQAIRRYGLDFNILHGHIDEIQGQAFGSLAIMATGELADVKAAMEYLQAQGVVVEEFEHVV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CH10_SYNE7
Sequence: MAAVSLSVSTVTPLGDRVFVKVAEAEEKTAGGIILPDNAKEKPQVGEIVAVGPGKRNDDGSRQAPEVKIGDKVLYSKYAGTDIKLGNDDYVLLSEKDILAVVA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGA_NOVAD
Sequence: MTIKVLSVASEAVPLVKTGGLADVAGALPSAVAPHGVGMTTILPGYPAVMKALARPRALHTWNSLLGEKARLVSGKIDGHPLLVLDAPAFFQRDGTPYVDSSGRDWADNWRRFAAFGRAAADVAGGAVKGRAFDLVHAHDWQAAMALAYLRFAPPPGGRRVPSVMTIHNMAFQGHYGADLFPALGLPPQAWAMDGVEYHGGVGYLKAGLEAASAITTVSPTYAREIRTPEFGMGLEGLVVSRGNRVSGIVNGIDTAQWNPETDPALAARFGVKSLARRVTNKRALEAEFALEADDGPLFVVITRLTWQKGIDVLLECIDHLVGIGGRLALLGSGDKAMENAFHAAATRHPGKVGVRIGYDEALSHRMQAGGDAILVPSRFEPCGLTQLYGLAYGCVPVVARTGGLADTVIDANLAAVMAGVATGVQFEGVNYPSVSDAISRAVTLYRQPDVWRAMQRAGMKTDFSWSRSGKAYADLYAALIAEDQ
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: Y1607_METJA
Sequence: MKIAMVTWEYPPRIVGGLAIHCKGLAEGLVRNGHEVDVITVGYDLPEYENINGVNVYRVRPISHPHFLTWAMFMAEEMEKKLGILGVDKYDVIHCHDWMTHFVGANLKHICRMPYVQSIHSTEIGRCGGLYSDDSKAIHAMEYLSTYESCQVITVSKSLKEEVCSIFNTPEDKVKVIYNGINPWEFDINLSWEEKINFRRSIGVQDDEKMILFVGRLTYQKGIEYLIRAMPKILERHNAKLVIAGSGDMRDYLEDLCYQLGVRHKVVFLGFVNGDTLKKLYKSADVVVIPSVYEPFGIVALEAMAAGTPVVVSSVGGLMEIIKHEVNGIWVYPKNPDSIAWGVDRVLSDWGFREYIVNNAKKDVYEKYSWDNIAKETVNVYKIAMEMMGR
What are the official names of this protein?
Uncharacterized glycosyltransferase MJ1607.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: PG099_MONPV
Sequence: MENVPNVYFNPVFIEPTFKHSLLSVYKHRLIVLFEVFVVFILIYVFFRSELNMFFMPKRKIPDPIDRLRRANLACEDDKLMIYGLPWITTQTSALSINSKPIVYKDCAKLLRSINGSQPVSLNDVLRR
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG094, EFC protein OPG094, Protein L5.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG099 family.