PharMolix/UniProtQA huggingface dataset:
Protein: RGS16_MOUSE
Sequence: MCRTLATFPNTCLERAKEFKTRLGIFLHKSELSSDTGGISKFEWASKHNKERSFSEDVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDLAAQASATSTSAPSGSPAEPSHT
What is the function of this protein?
Regulates G protein-coupled receptor signaling cascades (PubMed:9079700).  Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10373502).  Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha (PubMed:8917514).  May regulate extra and intracellular mitogenic signals.
What are the official names of this protein?
Regulator of G-protein signaling 16, RGS16, A28-RGS14P, Retinal-specific RGS, RGS-r, Retinally abundant regulator of G-protein signaling.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: H6S1A_DANRE
Sequence: MNLLTGRNMVERSSKFLFIVVGSVLFMLILYQYVAPGMMNFGSPHGYMLEDDADLFPTPDPHYVKKFYFPIRDLERTVDFEIKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKKESRMKNQRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNMSFIPEKKRAQVLLESAKKNLRDMAFFGLTEFQRKTQYLFERTFRLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMQLYDYARDLFQQRYMYKRQLERREQRLKNQPLFPFRRTSSSDSTFRDDAPESEGSRLPTEDYMNHIINRW
What is the function of this protein?
6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
What are the official names of this protein?
Heparan-sulfate 6-O-sulfotransferase 1-A, HS 6-OST-1A, HS6ST-1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: Y2082_PSEA8
Sequence: MDPKLLDILACPLTKGPLVLSEDKTELISKQAGLAYPIRDGIPVMLESEARSLNVDERLDK
What are the official names of this protein?
UPF0434 protein PLES_20821.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: RK12_THAPS
Sequence: MSEKINQIVEELKTLTLLEASELVAAIEETFGVDASASTGGGVVMAVAPAAAEEVEEKTEFTVMLDEVPADKKIAVLKVVRTLTGLGLKEAKELVESTPKMVQEGLGKDAAEDAKKQIEDAGGKVSLT
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MDJ1_YEAST
Sequence: MAFQQGVLSRCSGVFRHHVGHSRHINNILYRHAIAFASIAPRIPKSSFHTSAIRNNEAFKDPYDTLGLKKSATGAEIKKAYYKLAKKYHPDINKEPDAEKKFHDLQNAYEILSDETKRQQYDQFGPAAFGGGGAAGGAGGGSGSPFGSQFHDFSGFTSAGGSPFGGINFEDLFGAAFGGGGRGSGGASRSSSMFRQYRGDPIEIVHKVSFKDAVFGSKNVQLRFSALDPCSTCSGTGMKPNTHKVSCSTCHGTGTTVHIRGGFQMMSTCPTCNGEGTMKRPQDNCTKCHGEGVQVNRAKTITVDLPHGLQDGDVVRIPGQGSYPDIAVEADLKDSVKLSRGDILVRIRVDKDPNFSIKNKYDIWYDKEIPITTAALGGTVTIPTVEGQKIRIKVAPGTQYNQVISIPNMGVPKTSTIRGDMKVQYKIVVKKPQSLAEKCLWEALADVTNDDMAKKTMQPGTAAGTAINEEILKKQKQEEEKHAKKDDDNTLKRLENFITNTFRKIKGDKKN
What is the function of this protein?
Plays a role in mitochondrial biogenesis and protein folding.
What are the official names of this protein?
DnaJ homolog 1, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL35_CERS4
Sequence: MPKMKTKSAAKKRFSFTATGKVKAGPAGKRHGMIKRSTKFIRDVTGTMILSDADAKIVKKYMPYDR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: O10K2_HUMAN
Sequence: MERVNETVVREVIFLGFSSLARLQQLLFVIFLLLYLFTLGTNAIIISTIVLDRALHIPMYFFLAILSCSEICYTFIIVPKMLVDLLSQKKTISFLGCAIQMFSFLFLGCSHSFLLAVMGYDRYIAICNPLRYSVLMGHGVCMGLVAAACACGFTVAQIITSLVFHLPFYSSNQLHHFFCDIAPVLKLASHHNHFSQIVIFMLCTLVLAIPLLLILVSYVHILSAILQFPSTLGRCKAFSTCVSHLIIVTVHYGCASFIYLRPQSNYSSSQDALISVSYTIITPLFNPMIYSLRNKEFKSALCKIVRRTISLL
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 10K2, Olfactory receptor OR1-4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UPP_XANOM
Sequence: MNIVEVRHPLVQHKIGLLRDASLSTKGFRELVTELGTLLAYEATANLETESHTQPGWAGPVNVQRIAGAKITLVPILRAGLGMLPGVLALIPTARVSVVGLQRDEETLQPVPYFERLTGRLEERDALILDPMLATGGTLIATIDMLKRAGARRIKGIFLVAAPEGLKALEAVHPDVEVYTAAIDDHLNDKGYILPGLGDAGDRIFGTRVE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: Y1566_STAAB
Sequence: MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPIGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
What are the official names of this protein?
UPF0173 metal-dependent hydrolase SAB1566c.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: MPS1_YEAST
Sequence: MSTNSFHDYVDLKSRTNTRQFSDDEEFTTPPKLSNFGSALLSHTEKTSASEILSSHNNDKIANRLEEMDRSSSRSHPPPSMGNLTSGHTSTSSHSTLFGRYLRNNHQTSMTTMNTSDIEINVGNSLDKSFERIRNLRQNMKEDITAKYAERRSKRFLISNRTTKLGPAKRAMTLTNIFDEDVPNSPNQPINARETVELPLEDSHQTNFKETKRNTDYDSIDFGDLNPIQYIKKHNLPTSDLPLISQIYFDKQREENRQAALRKHSSRELLYKSRSSSSSLSSNNLLANKDNSITSNNGSQPRRKVSTGSSSSKSSIEIRRALKENIDTSNNSNFNSPIHKIYKGISRNKDSDSEKREVLRNISINANHADNLLQQENKRLKRSLDDAITNENINSKNLEVFYHRPAPKPPVTKKVEIVEPAKSASLSNNRNIITVNDSQYEKIELLGRGGSSRVYKVKGSGNRVYALKRVSFDAFDDSSIDGFKGEIELLEKLKDQKRVIQLLDYEMGDGLLYLIMECGDHDLSQILNQRSGMPLDFNFVRFYTKEMLLCIKVVHDAGIVHSDLKPANFVLVKGILKIIDFGIANAVPEHTVNIYRETQIGTPNYMAPEALVAMNYTQNSENQHEGNKWKVGRPSDMWSCGCIIYQMIYGKPPYGSFQGQNRLLAIMNPDVKIPFPEHTSNNEKIPKSAIELMKACLYRNPDKRWTVDKVLSSTFLQPFMISGSIMEDLIRNAVRYGSEKPHISQDDLNDVVDTVLRKFADYKI
What is the function of this protein?
Involved in the regulation of the onset of mitosis.  Involved in a pathway that coordinates cell proliferation and differentiation.  Implicated in spindle pole body (SPD) duplication.  Dual specificity kinase that can phosphorylate serine, threonine and tyrosine residues.  Phosphorylates the SPC29 and SPC110 spindle pole body components.
What are the official names of this protein?
Serine/threonine-protein kinase MPS1, Monopolar spindle protein 1, Regulatory cell proliferation kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: KTHY_BIFLD
Sequence: MSGLFVSFEGVDGVGKTTQVERLRAYLEAQGRTVVVTREPGGTALGKAIRQLLLHGVDGGAVDIAPRAEALLFAADRAQHVAETIRPALERGEVVITDRYLDSSLAYQAGGRELTPEEIRSLSMWATNNLLPDRTYLLDMDPALSHNRLEHAEDRMESAGSDFQSRTRQAFLDLAAAEPNRFRVIDASQSIEAVWAAIESDIKELA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ATPA_BRYMA
Sequence: DIIMSTNTFSEEAEALLKEALETYLKEFA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: MSBA_ECOL6
Sequence: MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGFGKTDRSVLMWMPLVVIGLMILRGITSYISSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMMFYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLLEHRGVYAQLHKMQFGQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AREA_GIBFU
Sequence: MSTSVSIATSSPVLTMNPIITEHDFRFPRRPSAWPGAAIHNAPTQRTXNSNRIPNSRDASASFKEHKTDMATTYSLARQGLGGSALFPFLQNGLADSDRSIDRMQQDDPLATQVWKFFARTKHQLPSQHRMENLTWRMMALNIRRHKEEQQQRQDEADARRKKNMDAGSRAFRLGRPMMQSSPSGIAQLRKSSENNLAQPDAMNLDDFIFSDNSGSPINFASPEGDKMVDDRSGSSMASAIPIKSRKEPSLQNFVPQSVPVQPAHQATQGSEFNYVNRHLRKTSIDDRRTRKRPANFSPQVPAVNSTAAQNDLDLDSELHDYSLDQPNQAGIPQQSNGSNVPFNIDTFMENDSMVNNGNFQQNFSFSPSTSPMIPHGPFSGMYHNSSVPSASMSNNNNNSDFYSPPASAYPSNVSTPHPVPEQEGFYFGSQDARTQRPQGFQQSIGSMLSQQFMYGGSNGNSGSTMFSAPGTASESMSAYSTAPSSFGHIDPSQVFQNEQAVTSPTIQMPQDNMFSFGADSDDEDNNAFADRNVSMQKDMSSSLDESGAMGWDASLPGQFSTQAARFPGGPTRKQVMIGGTTTDFVDNNGDWESNGLERSQSQSFRGGNLRRQHPKLPRNASTPVHFGGQQNGFEQLAQSMQSSPAGDGNGTMSGFSSVAPSRPSSPPMSKQGSTTNLQAAAGNGNDGNAPTTCTNCFTQTTPLWRRNPEGQPLCNACGLFLKLHGVVRPLSLKTDVIKKRNRGSGTNVPVGGSSTRSKKTASTLNSRKNSTLSMSTATANSTKPNSSNPTPRVTTPPATSQPPSSKDVDSPVSGTTSGANTAGSTPNSHFGGPGPSSGAVGGKGVVPIAAAPPKTSPGPGASSMSMQRPATASSKRQRRHSKSIGGDVPVSMDIDSPDSTSSIDGPRPFGSSAGLSSLPGGMSASSFNLNQRPSTLGSATGMISMSGGQTSSLIGSSAGPQEWEWLTMSL
What is the function of this protein?
Major nitrogen regulatory protein.  Positively acting regulatory gene of nitrogen metabolite repression (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein areA.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACYP_AERHH
Sequence: MGEQSFVVRVWGLVQGVGFRYFTRERALQLGLRGHAYNLEDGSVEILICGPEQSVQMMLGWLERGPRTAEVTRMEYEVAPPPKGSGFHTN
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RL11_ORYSJ
Sequence: MASEKKQSNPMREIKVQKLVLNISVGESGDRLTRASKVLEQLSGQSPVFSKARYTVRSFGIRRNEKIACYVTVRGEKAMQLLESGLKVKEYELLRRNFSETGCFGFGIQEHIDLGIKYDPSTGIYGMDFYVVLERAGYRVARRRRCKSRVGIQHRVTKEDAMKWFQVKYEGVILNKAQANTS
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SGCA_MOUSE
Sequence: MAAAVTWIPLLAGLLAGLRDTKAQQTTLHLLVGRVFVHPLEHATFLRLPEHVAVPPTVRLTYHAHLQGHPDLPRWLHYTQRSPYNPGFLYGSPTPEDRGYQVIEVTAYNRDSFDTTRQRLLLLIGDPEGPRLPYQAEFLVRSHDVEEVLPTTPANRFLTALGGLWEPGELQLLNITSALDRGGRVPLPIEGRKEGVYIKVGSATPFSTCLKMVASPDSYARCAQGQPPLLSCYDTLAPHFRVDWCNVSLVDKSVPEPLDEVPTPGDGILEHDPFFCPPTEATDRDFLTDALVTLLVPLLVALLLTLLLAYIMCFRREGRLKRDMATSDIQMFHHCSIHGNTEELRQMAASREVPRPLSTLPMFNVRTGERLPPRVDSAQMPLILDQH
What is the function of this protein?
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
What are the official names of this protein?
Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin.
What is the protein family that this protein belongs to?
Belongs to the sarcoglycan alpha/epsilon family.
What are the subcellular locations of this protein?
Cell membrane, sarcolemma; Single-pass type I membrane protein. Cytoplasm, cytoskeleton.
Protein: GHC2_RAT
Sequence: MIACRMSSQDLSITAKLINGGIAGLVGVTCVFPIDLAKTRLQNQQGKDVYKGMTDCLVKTARAEGFLGMYRGAAVNLTLVTPEKAIKLAANDFLRQLLMQDGTQRNLKMEMLAGCGAGICQVVITCPMEMLKIQLQDAGRLAVCQQASASATPTSRPYSTGSTSTHRRPSATLIAWELLRTQGLSGLYRGLGATLLRDIPFSIIYFPLFANLNQLGVSELTGKASFTHSFVAGCAAGSVSAVAVTPLDVLKTRIQTLKKGLGEDTYRGVTDCARKLWTQEGAAAFMKGAGCRALVIAPLFGIAQGVYFIGIGERILKCFE
What is the function of this protein?
Responsible for the transport of glutamate from the cytosol into the mitochondrial matrix with the concomitant import of a proton (symport system).
What are the official names of this protein?
Mitochondrial glutamate carrier 2, GC-2, Glutamate/H(+) symporter 2, Solute carrier family 25 member 18.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS13_PYRHO
Sequence: MVDFRHIVRVAGVDLDGNKQLRWALTAIKGVGINFATMVCRVAGLDPFMKAGYLTDEQVKKIEEILQDPVSHGIPRWAVNRPKDYETGKDLHLITAKLDMAIREDIMRLRRIRAYRGIRHELGLPVRGQRTRSNFRRGQTVGVSKKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MURG_BRASB
Sequence: MTSSAPLILLAAGGTGGHLFPAEALGVELIKRGYRVRLVTDARALRYSGLFTKDMIDVVPSETVRSRSPVALARTALLLGTGTLAAFNLMRRLKPAAVIGFGGYPTVPPLLAARLAGVPSLIHDANAVLGRANRFLSAHVKAIATSLPGVLDRDPALSGKTTTVGTPMRPAILEAAAVPYAAPETAGPLRLLVVGGSQGARVMSDVVPGAIERLEPALWSRLVLTQQVRQEDMARVRAVYDRLKINAELQPFFTDLPARLAANHLVISRSGAGTVAELAAIGRPSILVPLPGAIDQDQYANAGVLSDANAAIRIVQSDFTSDRLASEISALAAEPVRLAAMAQAARAAGRLDAAERLADLVIKTAGL
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GLN1B_RHIME
Sequence: MTTANEVLKQIKENDVKFVDLRFTDPKGKLQHVTMDVVCVDEDMFADGVMFDGSSIGGWKAINESDMVLMPDPETAHMDPFFAQSTMVIFCDILDPVSGEAYNRDPRGTAKKAEAYLKASGIGDTVFVGPEAEFFVFDDVKYKADPYNTGFKLDSSELPSNDDTDYETGNLGHRPRVKGGYFPVPPVDSSQDMRSEMLTVLSEMGVTVEKHHHEVAAAQHELGVKFDALVRNADKMQIYKYVVHQVANAYGKTATFMPKPIFGDNGSGMHVHLSIWKDGKPTFAGDEYAGLSESCLYFIGGIIKHAKALNAFTNPSTNSYKRLVPGYEAPVLLAYSARNRSASCRIPFGTNPKAKRVEVRFPDPTANPYLAFAAMLMAGLDGIKNKLHPGKAMDKDLYDLPPKELKKIPTVCGSLREALESLDKDRKFLTAGGVFDDDQIDSFIELKMQEVMRFEMTPHPVEFDMYYSV
What is the function of this protein?
Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I beta, GSI beta.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VE2_HPV16
Sequence: METLCQRLNVCQDKILTHYENDSTDLRDHIDYWKHMRLECAIYYKAREMGFKHINHQVVPTLAVSKNKALQAIELQLTLETIYNSQYSNEKWTLQDVSLEVYLTAPTGCIKKHGYTVEVQFDGDICNTMHYTNWTHIYICEEASVTVVEGQVDYYGLYYVHEGIRTYFVQFKDDAEKYSKNKVWEVHAGGQVILCPTSVFSSNEVSSPEIIRQHLANHPAATHTKAVALGTEETQTTIQRPRSEPDTGNPCHTTKLLHRDSVDSAPILTAFNSSHKGRINCNSNTTPIVHLKGDANTLKCLRYRFKKHCTLYTAVSSTWHWTGHNVKHKSAIVTLTYDSEWQRDQFLSQVKIPKTITVSTGFMSI
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PTH_KORVE
Sequence: MKLIVGLGNPGMQYQFTPHNLGFLAVDRIAEKYGIRVANRNCKALTGRGVIEGVDVVLAKPETYMNLSGASVQELVSELEIDGTKDMIVIYDDLDLPYGSIRVRERGSAGGHNGVQSIIGALDTQEFLRIRIGIAPEFKLSDGASYVLSQLKKSQLPVVDQALDDAAEAVKVILREGPGPAMNRFNRKPEPPESGGEVAAK
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_BACCR
Sequence: MEARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLDDKISNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_STRZJ
Sequence: MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEIILGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEAYDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHRIKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: LEG1_BUBBU
Sequence: MACGLVASNLNLKPGECLRVRGEVAPDAKSFLLNLGKDDNNLCLHFNPRFNAHGDINTIVCNSKDGGAWGAEQREVAFPFQPGSVVEVCISFNQADLTVKLPDGHEFKFPNRLNLEAINYMSAGGDFKIKCVAFD
What is the function of this protein?
Lectin that binds beta-galactoside and a wide array of complex carbohydrates.  Plays a role in regulating apoptosis, cell proliferation and cell differentiation.  Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.  Strong inducer of T-cell apoptosis.
What are the official names of this protein?
Galectin-1, Gal-1, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, Galaptin, Heart galectin-1, BfHG-1, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, S-Lac lectin 1.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm. Secreted. Note=Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: GATB_VANPO
Sequence: MLKVSKRYYGFQSKSPFQLLPDFRLKCGLEIHTQLNTKFKLFSFSTNDPFHSIDSPNSNVSFFDAALPGTQPILNYEAVIDAIKLSLALNCDINANSQFDRKHYFYGDQPLGYQITQHYSPISSNGKLSLFENIDNIDQSQKDIGIIQLQIEQDTGKSMYDDSKHFTRIDLNRSNVPLIEMVTKPDFTDLKQVRSFIKKYQNLVRHLKISSGDLETGAMRVDVNLSINDYARVELKNLPNTSSIVNAIKYEYNRQVEIIKNGSADELLTSPETRSWTGVKTVKLRSKETTIDYRYLPDPELPRVILDNDVITNISNSIPTLPDELLSRLISKPYNLSMKDAKILVLNSNGQNEMYTQEELQNFYLKVFDCYYNVVGEKLNHKLPVNWIIHELIGSLNKLELPLSKVLPKLSPEKFSEFIVLIHNKEISNTSAKLLLFHVLNQIKENDHSIREINFDSLIEEFELKPATNASKVDLTELCQTIITELNNEKLLNDIISGKKKNSIQYLVGLGMRASQGTLSPQSLEETFKKILQVKW
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: VHED_BPS76
Sequence: MFKRKSTAELAAQMAKLAGNKGGFSSEDKGEWKLKLDNAGNGQAVIRFLP
What is the function of this protein?
Binds preferentially to single-stranded DNA and therefore, destabilizes double-stranded DNA.  It is involved in DNA replication, repair and recombination.  Binds ss-DNA as the replication fork advances and stimulates the replisome processivity and accuracy.
What are the official names of this protein?
Single-stranded DNA-binding protein, Gp32, Helix-destabilizing protein.
Protein: PP408_ARATH
Sequence: MYIEIASSSSLSLPLLPLTRPHIYTSIPFSTIPEARQRNLIFTVSASSSSESTQNKKVWRKQPEKNTTSSFQALRKHRRYQRSAFLDHNVDMDELLASIHQTQNEKELFSLLSTYKDRQLSIRFMVSLLSRENDWQRSLALLDWVHEEAKYTPSVFAYNVVLRNVLRAKQFDIAHGLFDEMRQRALAPDRYTYSTLITSFGKEGMFDSALSWLQKMEQDRVSGDLVLYSNLIELSRRLCDYSKAISIFSRLKRSGITPDLVAYNSMINVYGKAKLFREARLLIKEMNEAGVLPNTVSYSTLLSVYVENHKFLEALSVFAEMKEVNCALDLTTCNIMIDVYGQLDMVKEADRLFWSLRKMDIEPNVVSYNTILRVYGEAELFGEAIHLFRLMQRKDIEQNVVTYNTMIKIYGKTMEHEKATNLVQEMQSRGIEPNAITYSTIISIWGKAGKLDRAATLFQKLRSSGVEIDQVLYQTMIVAYERVGLMGHAKRLLHELKLPDNIPRETAITILAKAGRTEEATWVFRQAFESGEVKDISVFGCMINLYSRNQRYVNVIEVFEKMRTAGYFPDSNVIAMVLNAYGKQREFEKADTVYREMQEEGCVFPDEVHFQMLSLYSSKKDFEMVESLFQRLESDPNVNSKELHLVVAALYERADKLNDASRVMNRMRERGILKPFPG
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g39980, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.