PharMolix/UniProtQA huggingface dataset:
Protein: RL35_XENTR
Sequence: MAKIKARDLRGKKKEELLKQLDDLKVELSQLRVAKVTGGAASKLSKIRVVRKSIARVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRALRRRLNKHEEGLRTKKQQRKDRLFSARKFAVKA
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PE2R3_HUMAN
Sequence: MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRYHTNNYASSSTSLPCQCSSTLMWSDHLER
What is the function of this protein?
Receptor for prostaglandin E2 (PGE2) (PubMed:8307176, PubMed:7883006, PubMed:8117308, PubMed:8135729, PubMed:7981210).  The activity of this receptor can couple to both the inhibition of adenylate cyclase mediated by G(i) proteins, and to an elevation of intracellular calcium (PubMed:7883006, PubMed:8117308, PubMed:8135729, PubMed:7981210).  Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS).  Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation.  Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration.  Not required for normal kidney function, normal urine volume and osmolality (By similarity).
What are the official names of this protein?
Prostaglandin E2 receptor EP3 subtype, PGE receptor EP3 subtype, PGE2 receptor EP3 subtype, PGE2-R, Prostanoid EP3 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GID8_CHICK
Sequence: MSYAEKPDEITKDEWMEKLNNLHIQRADMNRLIMNYLVTEGFKEAAEKFRMESGIEPSVDLETLDERIKIREMILKGQIQEAISLINSLHPELLDTNRYLYFHLQQQHLIELIRQRETEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDNPEESPFGDLLNMMQRQKVWSEVNQAVLDYENRESTPKLAKLLKLLLWAQNELDQKKVKYPKMTDLSKGTIEEPK
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.
What are the official names of this protein?
Glucose-induced degradation protein 8 homolog.
What is the protein family that this protein belongs to?
Belongs to the GID8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the cytoplasm in the absence of Wnt stimulation and in the nucleus in the presence of Wnt stimulation.
Protein: MSBA_DESPS
Sequence: MTNKEIIKRLYHEIIPYKIPLFIAMFAMIVVAALTGAQAYLVKDLLDKIFMEKDVFFLQILPLIIIAIFFTKGVLYYTYAIILERVGQSIIRDFRLKIFAHIHRQSLSFFHNTPTGTLISRVLSDVALMQQAVSTVIIQLLRDFFQVIFLLGVIFYMNWKLALICFLIIPLAAIPIVKFGKIFRKLSTKTQEETAEVSNMLHETISGSRIVKAFCREDYEVERFHRQVETLFTITMKNAKYRVFQSPLMEIIGGFAVAGIIWVGGSEVINGSATPGTFFAFLTAMITAYDPVKRVSQVNSTIQQGLASAQRVFAILDIKPEIEDKPEATSLAPFKESIEFHDVSFSYGTEKILSHINLKVPAGEALAIVGPSGGGKTTLTNLIPRFIDLQEGSITIDGTDIRDVTTNSLRNQIAMVTQQTILFNDTIRNNIAYGKDSCTEEEIRRAAKAAHALTFIEELPNGFDTALGEGGAKLSGGQRQRISIARALLADAPILILDEATSALDTESEREVQKALENLMQNRTTFVIAHRLSTIKNASRIVVVKKGKIVEEGSHEELLKLEGEYQLLYNMQ
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Translocates lipid A-core from the inner to the outer leaflet of the inner membrane.  Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
What are the official names of this protein?
ATP-dependent lipid A-core flippase, Lipid A export ATP-binding/permease protein MsbA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SHGR6_ARATH
Sequence: MASSSLGSSIPAPEAVQLLVSSLADDSSVVREASMASLRDIASLNPLLVLDCCYAVSRGGRRRFGNMAGVFQVMAFSVGALEKGESDSVFMGKLAKIATAEIISSKELNADWQRQASGLLVSIGTHFPDLMMEEIFLHLSGPATAAPAMVQILADFASSDALQFTPRLKGVLSKVSPILGNVRDIHRPIFANAFKCWSQAVWLYITDLTSDSPLDSDVMSFLNSVFELLLRVWAVSRDHKVRVSTVDALGQMVGLITRTQLKSALPRLIPAILELYKKDHDDALLATCSLHNLLNASLLSESGPPLLDFEDLTIVLSTLLPVIGINNERKRFSDISVGRKTYNEVQRCFLTVGLVYPEDLFTFLLNKCKLKEDPLTFGALCILKHLLPRLFEAWHSKRPLLVDTASSLLDEQSLAVRKALSELIVVMASHCYLVGPSGELFVEYLVRHSAIGESDHLKAKGELVSPTQLRAVCGKGLLLLTVTIPEMELSDFNAKEYMKLQYILWPFLLKMIIPKVYTGAVASVCRCITELCRRRSSTTPMLIECKARADIPNPEELFTRLVVLLHNPLAKEQLASQILTVLGYLSPLFPKNISMFWQDEIPKMKAYVYDTEDLKLDPTYQETWDDMIINFLAESLDVTQDADWVISLGNSFAKQYILYAPDDDHAALLHRCIGILLQKVNDRAYVRDKIDWMYEQADISIPANRLGLAKAMGLVAASHLDTVLEKLKIIVDNVGQSIFQRILSLFSESYKTEDSDDIHAALALMYGYAAKYAPSSVIEARIDALVGTNMLSRLLHVRQQTAKQAVITAIDLLGRAVINAAETGATFPLKRRDQMLDYILTLMGRDENEGFAESSLEVLHTQALALNACTTLVSVEPKLTIETRNRVMKATLGFFALPNDPSDVISPLIDNLVTLLCAILLTSGEDGRSRAEQLLHLLRQLDQYVSSPIDYQRKRGCVAVHEMLLKFRKLCVGGYCALGCSGDCPHRKYADRSMQGNFSNLPSVFLFPDREVLCLGDRVITYLPRCADTNSEVRKISAQILDQFFSISLSLPKAVLTSGLDSEDSYKALSSLEDVIAILKSDASIDPSEVFNRIVSSICSLLTEHELVAALHSCTAAICDKIRQSAEGAIQAVTEFVSRRGSQLSDNDISRTTHSLLSAAVHITDKNLRVEAIGAISALAENTQSSIVFNEVLATAGKDIVTKDITRMRGGWPMQDAFYAFSQHTELSVLFMEHLISILNRSSLVKSDSHKGENTSSSSETHVEDDILQAAIFALTAFFRGGGKIGKKAVEKSYSSVVGALTLQLGSCHGLASSGQQDPLRVLLTSFQAFCECVGDLEMGKILARNGEQIEKEKWVGLIGDIAGCISIKRPKEVRHICMILTKALNRPQRFQREAAAAALSEFIRYSGDFSSVMEEMVEALCRHVSDDSPTVRRLCLRGLVQMPSACMSHYTTQVIGVILALLDDLDESVQLTAVSCLLMVTESASNDAVEPILLNLSVRLRNLQVSMDPKMRANAFSALGALSKYATGGQREGFVEQIHSTLPRLVVHLHDDDPSIRQACRVTLKRFAPLVDIINYSTLYDSRAFGSEDRTDYENFVRDLSKHLVQESERVDTYMASTIQAFDAPWPVIQANAIHFSTTMLSLSEDQHIISLYYPQVFETLVSKMTRSQDSVVRAACSSAFGLLLRSSKSTLWRGARLDGTDSGRKANDLESVKK
What is the function of this protein?
Involved in inflorescence stems gravitropism, by modulating vacuolar membrane (VMs) dynamics in gravity-sensing cells (e. g.  endodermal cells) during the amyloplast sedimentation process.
What are the official names of this protein?
Protein SHOOT GRAVITROPISM 6.
What are the subcellular locations of this protein?
Vacuole membrane.
Protein: SYH_XANOP
Sequence: MIKPRTPPGIMELLPREQIAFQRMLDVIRRNYERFGFLPIETPVFELSDVLLTKSGGETERQVYFVQSTGALANAAAAADEGAENGGLPELALRFDLTVPLARYVAEHEHDLSFPFRRYQMQRVYRGERAQRGRFREFYQCDIDVIGKDALSIRYDAEVLAVIHAVFAELGIGDFKVQLNNRKLLRGFFESLGVAEGELQLAVLREVDKIDKRGADYVRDTLVGEGFGIAAEQVARILAFVAVRSEGHADALAQLQALEASVGASATLGEGIAELREVLELVKALGVPERAYCLNFSIARGLDYYTGTVYETTLTDHPQIGSICSGGRYESLASHYTKSRLPGVGISIGLTRLFWQLREAGLIQGIAESSVQAMVALMDETRLDDVLDIARRLRIAGINTEVQMEPKKVGKQFQYAARAGIRFVVLAGDDELARGVVAVKDLVREQQFDVARDELASTLLVELEQAKAMP
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_GRABC
Sequence: MPSLLLWTGLGNPEPGMALQRHNIGFMAVDAIAQRHGFTPWRNRFKGLTAEGTLAGRKIILLKPMTYMNASGESVQPATAFFKLPPEAVSAFHDELDLAPGKVRVKRGGGAAGHNGLRSMDRMLGTPEYWRVRLGIGHPGSKERVHGHVLGNFAKSDQEWLGPLLEAVADAAPLLAEGRAEDFMTRIALLTHRQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPHB3_XENLA
Sequence: MLPAVFVILALSAVQGLEETLMDTKWTTSELAWVAYPDSGWEEVSGYDEASNPIRTYQVCNVRDSNQNNWLRTQFIPRQDVQRVYVELKFTVRDCNSLPNLRGSCKETFNFFYYESDSDSASADSPFWMENPYIKVDTIAPDESFSRRDSGRVNTKIRSFGPISRAGFYLAFQDLGACVSLISVRVFFKKCPRTTAGFASFPETITGAEPTSLVIAPGTCVPNALEVSVPLKLYCNGDGDWMVPVGACTCAAGFEPAGKDTQCQACKRGTYKSKQGEGSCMPCPANSRAISSAATICSCQNGYYRADGESAETACTSVPSAPRQVISNVNETSVVLEWAEPGHLGGRDDVLYNVICKKCLERLCSRCDDNVQFWPRQLGVTQRLVSVSHLQAHTKYSFEIQAVNGVSGKSPHIPNYFTVNITTNQAAPSSVPMVQSHGSLANSLTLSWAPPESPNGIILDYEIKYYAKGHIGAGNTVTSQRTTVRMEGMTPDTVYVVQVRARTVAGYGAYSEPREFQTIAEDGDRSSLQEQVPMVVGSVTAGLIFIIAVVIIVIVCFSRKQRNDSESEYTEKLQQYMVPGMKLYIDPFTYEDPNEAVRDFAKEIDISCVKIEEVIGAGEFGEVCRGKLKQAGRREQFVAIKTLKAGYTEQQRRDFLGEASIMGQFDHPNIIRLEGVVTRSRPVMILTEFMENGALDSFLRMNDGQFTVIQLVGILRGIASGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLENSRSDPTYTSALGGKIPIRWTAPEAISYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAIEQDYRLPPPMDCPSALHQLMLDCWLRDRNLRPKFSQIVSSLDKLIRNAASLKVTSPGQAGVSQQLLDRTVPDYTTFPTVSDWLEAIKMGQYQENFLSAGFTSFHLVAQMTAEDLLRIGVTLAGHQKKLLNSVQDMRLQMSQTLPVQV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Generally has an overlapping and redundant function with EPHB2.  Like EPHB2, functions in axon guidance during development.  In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses.  May control other aspects of development through regulation of cell migration and positioning (By similarity).
What are the official names of this protein?
Ephrin type-B receptor 3, Tyrosine-protein kinase receptor TCK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite.
Protein: ISCA_ESCF3
Sequence: MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFHV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: NTP7A_XENLA
Sequence: MGLLERLRKEWFIVGIILVIAAAKLEPTVGVKGGPLKPEITITYIAVSAIFFNSGLSLKTEELTNALMHVKLHLFVQLFTLVFFPTAIWLFLQVLSLTPINEWLLKGLQTVSCMPPPVSSAVILTKAVGGNEAAAIFNSAFGSFLGIVVTPLLLLLFLGSSSSVPFTSIFSQLFMTVVVPLIIGQIVRRYIKDWLERKKPPFGAISSCVLLMIIYTTFCDTFSNPNIDLDTFSLVVIVFIIFFIQLAFMLLTFLFSTSKNSGFTPADTVAIVFCSTHKSLTLGIPMLKIVFVGYEHLSLISVPLLIYHPAQILLGSVLVPTIKSWMLSRQKALKLTRQPKIPL
What is the function of this protein?
Involved in teeth and skeletal development.  Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix.  Required for extracellular matrix mineralization.  Also involved in the regulation of cellular calcium homeostasis.  Does not show transport activity towards bile acids or steroid sulfates.
What are the official names of this protein?
Sodium/bile acid cotransporter 7-A, Na(+)/bile acid cotransporter 7-A, Solute carrier family 10 member 7-A.
What is the protein family that this protein belongs to?
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane.
Protein: SYW_RHOBA
Sequence: MRVLSGIQPTGRPHWGNYFGAIRQYIDLQEDNEGFYFIADLHALTTVREPEVLRENVMNAALDLLALGLDPSKANLFVQSDIPEVTELTWLLMTGTPMGLLERCHAFKEKKAKGLTADAGLFTYPVLMAADILAYDSQIVPVGVDQVQHIEVCRDLAGSFHHAFGETFVLPKAKTLDVGAKVPGTDGQKMSKSYNNTLPLFGEVKKIRKQIMRIVTDSRPMEDPKDPTDDHLFQLYQLFAGPAEVETMAAKYRAGGFGYGEIKKAVAEVSEEYFAPARAKREELESDLDTVRDILAEGAKRAREVAASVVDRARRNCGLR
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODR_HYPPI
Sequence: MFDIDFGILFPISWEQSPIFLAVGLIFAFATLSPWLRSGERLINGREGFEILWTNAKKRYQTKGRSVMEAGFSKYNDSFYMMTDSGTEMVLHPRYVDEIRNDPRLDFHRYMKTKGGEINRDLIQTKLTRSVGRLIGSISAEIEDALHNRWEEGEGEYEEYLLVLPPAEMHTEWHEIVLLSVMIPVVAQGVSKMFVGDPLCRNKDWIGMILRHTRSVQTALRSLRLWPYFLRPLAARFLPTCRQVTAEIEEARRIINPVLEKKRAEKLAMIQKGEKPPEPNTYMDWLEESDKDEFYDPVVAQLKISMAAIHATSDLLSQTIFSLCDSPELVKELRAEAVSVIGAYGWGKEAIYNLKLMDSVLKETQRLKPMQINLTRLALDRIKLSDGTVIPRGSKVLISCHNMWDSNVYPNANQYDGHRFYKLRQRAGMENSAQLSTPSPDHLGFGLGMYACPGRHIASTVMKVTLCHILLKYDFELAEGCTPRVIEYGSFLLADPTARVSIRRRKEEIQL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes nodulisporic acids (NA).  Nodulisporic acid A (NAA) and its chemically modified derivatives are of particular significance because of their highly potent insecticidal activity against blood-feeding arthropods and lack of observable adverse effects on mammals, in particular the tremogenicity associated with the paspaline-derived IDTs is not observed (PubMed:29283570).  The geranylgeranyl diphosphate (GGPP) synthase ggs1, localized outside of the cluster, is proposed to catalyze the first step in nodulisporic acid biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:29283570).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase nodC then forms 3-geranylgeranylindole (3-GGI) (PubMed:29283570).  Epoxidation by the FAD-dependent monooxygenase nodM leads to a single-epoxidized-GGI that is substrate of the terpene cyclase nodB for cyclization to yield emindole SB (PubMed:29283570).  The terminal methyl carbon, C28, of emindole SB is then oxidized by the cytochrome P450 monooxygenase nodW to produce nodulisporic acid F (NAF), the pentacyclic core of NAA (PubMed:29283570).  NAF is converted to nodulisporic acid E (NAE) via prenylation.  This step is probably performed by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  Several oxidation steps performed by the FAD-linked oxidoreductase nodO and one of the cytochrome P450 monooxygenase nodR, nodX or nodZ further convert NAE to nodulisporic acid D (NAD) (Probable).  NAD is substrate of cytochrome P450 monooxygenase nodJ to produce the precursor of nodulisporic acid C (NAC), converted to NAC by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  The FAD-dependent monooxygenase nodY2 then oxidizes NAC to nodulisporic acid B (NAB) (Probable).  Finally NAB is converted to NAA by one of the cytochrome P450 monooxygenases nodR, nodX or nodZ (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase nodR, Nodulisporic acid biosynthesis cluster protein R.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y690_STRP6
Sequence: MKLAVITDSTATLPIDLKQDKAIFSLDIPVIIDDETYFEGRNLSIDDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLAEEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDRTTAFIMVDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLIADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPRL
What is the function of this protein?
May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism.
What are the official names of this protein?
DegV domain-containing protein M6_Spy0690.
Protein: REXO4_YEAST
Sequence: MALSSNWQALLASESNPTSNGKNKQSNRKIRNVKKVSKTVNVSSTTQYAPRKRKNGSKIMDMVYNMNKEISKHEKDKLEGKVFEFNPNKANTSTTIKEPVKVGISEDTRINSNKSKEIGKYIAMDCEFVGVGPEGKESALARISIVNYFGHVVLDEFVKPREKVVEWRTWVSGIKPEHMKNAITFKEAQKKTADILEGRILVGHALKHDLEALMLSHPKSLLRDTSRHLPFRKLYAKGKTPSLKKLTREVLKISIQEGEHSSVEDARATMLLYKKEKTEFEKIHRNTFN
What is the function of this protein?
Exoribonuclease involved in ribosome biosynthesis.  Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5. 8S rRNAs.
What are the official names of this protein?
RNA exonuclease 4.
What is the protein family that this protein belongs to?
Belongs to the REXO4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: F90AE_HUMAN
Sequence: MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGDCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE
What are the official names of this protein?
Putative protein FAM90A14.
What is the protein family that this protein belongs to?
Belongs to the FAM90 family.
Protein: RL29_ECO24
Sequence: MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLKQVRRDVARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: BTBDG_HUMAN
Sequence: MIMSNTHKARLERRVTGSTNRWRLPKQPFSGDLLSLSQMCKALSIDFEEALRNPDRLCISQIQKFFFENFKNKDIQSGEADVILECLGFKWELHQPQLFQSETLAKLYLKALAQGTTHPLRELEELLRAQSPKKTKEKSPAKRIIISLKINDPLVTKVAFATALKNLYMSEVEINLEDLLGVLASAHILQFSGLFQRCVDVMIARLKPSTIKKFYEAGCKYKEEQLTTGCEKWLEMNLVPLGGTQIHLHKIPQDLLHKVLKSPRLFTFSEFHLLKTMLLWVFLQLNYKIQAIPTYETVMTFFKSFPENCCFLDRDIGRSLRPLFLCLRLHGITKGKDLEVLRHLNFFPESWLDQVTVNHYHALENGGDMVHLKDLNTQAVRFGLLFNQENTTYSKTIALYGFFFKIKGLKHDTTSYSFYMQRIKHTDLESPSAVYEHNHVSLRAARLVKYEIRAEALVDGKWQEFRTNQIKQKFGLTTSSCKSHTLKIQTVGIPIYVSFAFIFPAS
What are the official names of this protein?
BTB/POZ domain-containing protein 16.
Protein: APT_AZOC5
Sequence: MSPLPDLASVVRTIPDYPKPGVMFRDITTLLGNPQAFRRTVDELVQPWAGAKIDKVAGIEARGFIVGGAVAHQLSAGFVPIRKKGKLPHQTVRMAYALEYGQDEMEMHVDAVHPGERVILVDDLIATGGTAEGAVKLLRQIGAQVEAACFIVDLPDLGGAEKLRAMGVPVRTIMSFSGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_YERPP
Sequence: MTKQVEIFTDGSCLGNPGPGGYGAILRYKQHEKTFSAGYYLTTNNRMELMAAIVALEALTSPCEVTLSTDSQYVRQGITQWIHNWKKRGWKTADRKPVRNVDLWQRLDLAIQSHTIQWEWVKGHAGHPENERCDELARQGANSPTLDDTGYNPD
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEQA_MANSM
Sequence: MKIIEVDEELYQYIASQTKSIGESASDILRRLLNLPVSGVNLTAVDLTQSTMNSTNEEKGTQLPAEKNVVAETPKPSSEQEIRTPARKQSTQSIQHIVTKVKNLLQSEAFQEESKMVVRFLNILSVLYRTNPESFAQATEQETSQGRTRTYYARDEATLLAAGNHTKPRQIPDTPYWVITNTNSGRKMLMLERTMQFMELPEELIDEVRPYFAVV
What is the function of this protein?
Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle.  Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins.  Repression is relieved when the region becomes fully methylated.
What are the official names of this protein?
Negative modulator of initiation of replication.
What is the protein family that this protein belongs to?
Belongs to the SeqA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_MYCLE
Sequence: MSEKGRLFTSESVTEGHPDKICDAISDSILDALLAEDPCSRVAVETLVTTGQVHVVGEVTTLAKTAFADISNTVRERILDIGYDSSDKGFDGASCGVNIGIGAQSSDIAQGVNTAHEVRVEGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLARRLTEVRKNGVLPYLRSDGKTQVTIAYEDNVPVRLDTVVISTQHAAGVDLDATLAPDIREKVLNTVIDDLSHDTLDVSSVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNIVAAGLAERIEVQVAYAIGKAAPVGLFVETFGTEAVDPAKIEKAIGEVFDLRPGAIIRDLHLLRPIYAQTAAYGHFGRTDVELPWEQLNKVDDLKRAI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_DESPS
Sequence: MGKIIGIDLGTTNSCVSVMEGGEPKVIANVEGNRTTPSVVAFADNDERLVGMIAKRQAVTNPERTVYAAKRLIGRKFTDAEVQRSQEVSPFDIVEGISGSVAIQVEGHKYRPAEISAMVLGKMKQTAEEYLGEEVTEAVVTVPAYFNDSQRQATKDAGKIAGLDVKRIINEPTAASLAYGLDKKVEEKIAVFDLGGGTFDVSVLEIGDGVFEVKSTNGDTFLGGEDFDMRIVHWLADEFKREQGIDLRSDKMALQRLKEEAEKAKMELSTTVETDINLPFITADASGPKHLNIKLSRSKFETLVEDLVERTVGPCKTALKDAGLSASQIDEVILVGGMSRMPMVQKKVVEIFGKEPHKGVNPDEVVAIGAAIQGGVLQGDVKDVLLLDVTPLSLGIETLGGVTTKLIEKNTTVPTKKSQVFSTAADNQPAVSIHVLQGEREMAEGNKTIGRFELADIPTAPRGVPQIEVTFDLDANGILNVSAKDMGTGKEQSIKITASSGLTDEEIDRMTKDAELHADEDKKRKELVEARNSADGLIHSTEKTLKDLGDKVDAETKENVEKEIANVKTALEGDDVEAIKAAIEALTAASHKLAELMYQQASQETPGDGDAGAAGAKKKDDDDVVDADYEEVK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ISCA_YERPB
Sequence: MSISISDSAAQRVSAFLNHRGKGLGLRLGVRTSGCSGMAYVLEFVDEINDDDIVFEDKGVKVIIDGKSMVYLDGTELDFVKEGLNEGFKFNNPNVSNECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: CSS4A_HYDCU
Sequence: MKIYKVDKTLVSTNRIAMMEHKPLLVVREKDGGTPQVAVDPVGCKPGDWVICCGSSAARDATGVKGYPSDLTIVGIIDKWEVPQDADTTS
What is the function of this protein?
Probably forms vertices in the carboxysome, a polyhedral inclusion where RuBisCO (ribulose bisphosphate carboxylase, cbbL-cbbS) is sequestered.  Has been modeled to induce curvature upon insertion into an otherwise flat hexagonal layer of major carboxysome subunits.
What are the official names of this protein?
Carboxysome shell vertex protein CsoS4A.
What is the protein family that this protein belongs to?
Belongs to the CcmL/EutN family. CsoS4 subfamily.
What are the subcellular locations of this protein?
Carboxysome. Note=This bacterium makes alpha-type carboxysomes.