PharMolix/UniProtQA huggingface dataset:
Protein: GERPC_BACCE
Sequence: MNQDIYTYLHQLQQALQTQQAAILNLEDQVRQLQEELNELKNRPSSSVGKVEYKFDQLKVENLNGTLNIGLNPFSAKGQQIEDLQVDTETLKVNPETETNPDFYQGILQEMHRYLDEEAYNRILHFEQEERTPLDEMYRQMMVDDIKKQMEHRLPYYLSQAQSYEGISTDPDYLRDIIIQAMKQDIDKAFLSFIQHIPGNFRKE
What is the function of this protein?
Required for the formation of functionally normal spores.  Could be involved in the establishment of normal spore coat structure and/or permeability, which allows the access of germinants to their receptor.
What are the official names of this protein?
Probable spore germination protein GerPC.
Protein: LEPA_BIFLO
Sequence: MVVQHNQPGSTDQSVIRNFCIIAHIDHGKSTVADRILQLSGIVPEREMRDRFLDRMDIEQERGITIKSQAVRVPWTFDGTEYTLGMIDTPGHVDFTYEVSRALAACEGAVLLVDATQGIEAQTLSNLYMAIDHDLAIIPVLNKIDLPSAEPDKHAEEIAGLIGCEPSDVLRVSGKTGEGVADLLDQIVMDVPAPHGDPDAPARALIFDSVYDSYRGIVTYIRMEDGELHDREKVHMMGIGMTHDPIEIGVISPDMTRTKALGAGEVGYIITGAKDVSQSKVGDTLTSAVRPAAEPLPGYRDPKPMVYAGLFPIDNAQFPELRDALDKLKLNDAALIYTPETSVALGFGFRCGFLGLLHMEIVNERLSREFGLDLIQTAPNVTYDVTAEDGSQHHVTNPSEFPDGKIKKIVEPMVAADIITPKEFIGAVMDLCQDHRGIMGTMEYISTDRVEMHYRIPLAEIVFDFFDQLKSRTKGYASLDYHEDGEQSADLVKVDILIQGEKVDAFSAIVHRDKAYSYGVMMTKKLRSLIPRQQFEIPIQAAIGSRIIARENIRALRKDVLAKCYGGDITRKRKLLEKQKAGKKRMKMLGHVEVPQEAFIAALSTGEDSNDRDTKDKIRAAQKTEG
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OPS1_SCHGR
Sequence: MASASLISEPSFSAYWGGSGGFANQTVVDKVPPEMLYLVDPHWYQFPPMNPLWHGLLGFVIGVLGVISVIGNGMVIYIFSTTKSLRTPSNLLVVNLAFSDFLMMFTMSAPMGINCYYETWVLGPFMCELYALFGSLFGCGSIWTMTMIALDRYNVIVKGLSAKPMTNKTAMLRILFIWAFSVAWTIMPLFGWNRYVPEGNMTACGTDYLTKDWVSRSYILVYSFFVYLLPLGTIIYSYFFILQAVSAHEKQMREQRKKMNVASLRSAEASQTSAECKLAKVALMTISLWFFGWTPYLIINFTGIFETMKISPLLTIWGSLFAKANAVFNPIVYGISHPKYRAALEKKFPSLACASSSDDNTSVASGATTVSDEKSEKSASA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Opsin-1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPB_FUCVE
Sequence: MSIEKNNNIGYITQVIGPVIDAVFSSGVLPKIYNALEVEGKDGPIICEVQQLLGDNRVRAISMSATDGLQRGVKVYDTKAPISVPVGKTTLGRIFNVLGQPIDNLGDTPSNETLPIHRSAPAFTDLETRPAIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEKNLLESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDINKQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLGTEMGALQERITSTNQGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPLIVGDEHYKTAQLVKETLQRYKELQDIIAILGIDELSEEDRLVVDRARKIERFLSQPFFVAEVFTGSPGKYVDLESTIKGFNMILGGELDDLPEQAFYLVGDINEAISKAKTFNN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: DAPH_STACT
Sequence: MVKDFSAEEIIQYISDAKKSTPLKVYVNGVLGQVTFPDSFKVFGSENSKVIFCEASDWEDFYNDNKNYIEEVEIEMDRRNSAIPLKDLRNTNARIEPGAFIREHAVIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIEPPSASPVVIEDNVLIGANAVILEGVRVGEGAIVAAGAIVTQDVPAGAVVAGTPAKVIKQTSEVEDSKREIVSALRKLND
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: LKA41_PICGU
Sequence: MLRRPKVSPELDPSTLSNYGDFIVHKTQLDLAVDFDKNRVSSCVSLNVTNRTNTHQVVLDSSYLVIHSASINGISTPFDVAERQTLGSKVTIKIPPEMKISELTITIESETTYECTALQFLPAEATDGGVGPYLFSQCQAIHARSLFPCFDTPAVKCPYEMSVTSPYPSVMSGRPLGVSGNMYRFSQPVPIPSYLVAVASGDIKSAPIGPRSSVYCEPLKLEVCQHEFQADMEHFLQAAESLVFKYEWERYDALVLPSSFPYGGMENPNITFVTPTLISGDRENVDVIAHELAHSWSGNLVTNCSWEHFWLNEGWTVYLERRILGKLHGNATRDFSAIIGWTDLENSIAAMGPSAERWSMLVHNLKDGSDPDDAFSTVPYEKGSTLLYHIETLIGQEKFDKFIPHYFHTFRYKSLDTYQFIDCLYSFFADFKSVLDTIDWESWLYKPGMPPVKPDFDTSMVDQCYQLADKWYHHSLKNKFHKFSSEDIKSFTANQSVVFLDTLIAFDKLDFKWKHHLDALNTMASVYQEYSKSTNAEVLFRWYVLQVTGHNQEYYSRLGEWLGTVGRMKFVRPGYVLLNKVDRSMALHYFEKFHNRYHAICKSMVRRDWDLIKTK
What is the function of this protein?
Aminopeptidase that preferentially cleaves di- and tripeptides.  Also has low epoxide hydrolase activity (in vitro).  Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
What are the official names of this protein?
Leucine aminopeptidase 2-1, Epoxide hydrolase, Leukotriene A-4 hydrolase homolog 1, LTA-4 hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MDH_NOVAD
Sequence: MARKKIALIGAGNIGGTLAHLAAQKELGDIVLFDVVEGVPQGKALDLSQCGPVEGFDANIIGTNDYKGIAGADVIIVTAGVARKPGMSRDDLLGINLKVMKAVGEGIRDNAPDAFVICITNPLDAMVWALREFSGLPANKVVGMAGVLDSARFSTFLAWEFGVSIRDVNTFVLGGHGDTMVPVTQYSTVNGIPVPDLVKMGLSTQEKIDAIVQRTRSGGGEIVGLLKTGSAFYAPAASGIAMAEAYLNDQKRILPCAAYVDGEYGVNGLYVGVPVLIGANGVEKVIEIELDDEAKGNLQVSVDAVKELLEACKGIDPSLA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: BTUC_SALPK
Sequence: MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWLSARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLAGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGETSARQLGLPLWFWRNLLVVATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PFF1_COCP7
Sequence: MRRSTDPRNLLVRRGPLLVDGESAISELDPGFFPTGDAPKMSSTTRRRFNLIAFTPGPVTVISSLVYLALLIPLLLVHTIVPSAPKSNPKGVDLSEAWNDLQHLTSGFHPYNSHRNDEIHQWLLQRVGHILDASRKAHEDDAMGSVAPDVFVFDDQQSNLTFSGGGVGNKPITGVYFEGKNIIVYIRGLEDDKENWWDSPGGKPKGKGGVLVNAHYDSVSTGFGATDDGVGVVSVLQLIKFFTSPGNLPRKGLVLLLNNGEEDYLNGARAYSQHPLSKYTHTFLNLEGAGAGGRAALFRTTDIEVTRFYKSSPHPFGSVLAADGFKMGLIRSETDYAVFKGVLGLRGLDVAFIEPRARYHTDQDDVRHTSIDSVWHMLSAAIATTKGLVSYTGSEFDGRAPGKGMVNSGVGTHGVWFDLFGSSFAVFRLHTLFAISVTLLVVCPIVLFVIGIILSKMDKMYLFSIHETIPETKEKVSVRGLRGLFRYPIILVVSSGILIGLSYLLAKVNPFIVHSSSYAVWSMMLSSWIFMTWFLSCIADFFRPSALHRAYTFTWQLLVMWVLLVISTVYVNQHDIAAGYFIVFYFAGTFLATLISYLELFALPNKTRYAREQSQYPSRLGSNRSSRILSPSADELPTGGDNNGEIYDGEEEPTESSSLLGRQRRTTFANYTRTGRDLASSESGTYEDHSETGVFGEEQKWSASLPTWTWVLQFLFVGPVVIMFIGQLGLFLTSAMNQVGADGVGLLVVYIAIAVFSVLLLIPLSPFIHRFTYHVPTFLLLVFIATLIYNLAAFPFSAENRLKIFFVQELNLDTGRNQVSLTGVDPYVQDIIRAIPSASKENISCDSELDSGRRKCSWPGLAPEVVQDEPTDRWLSFNISKPSSQETKDTPVLHARLHVSGKNTRACRVNFERPIRDYSLPGSALDDRMPHTLPQGISEIRLWSRTWENVWTVDVQWDAEDMDELHGRVVCLWSDANQLGSIPALDELRLFAPPWVAISKLKDGLVEVSRGF
What is the function of this protein?
May be involved in vacuolar sorting and osmoregulation.
What are the official names of this protein?
Vacuolar membrane protease, FXNA-related family protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: GLNA_SQUAC
Sequence: MRICRSFLFLVKKCGNITPTIWRNQHTYKMATSASANLSKIVKKNYMELPQDGKVQAMYIWIDGTGEAVRCKTRTLDNEPKSIAELPEWNFDGSSTYQSEGSNSDMYLVPSAMFRDPFRRDPNKLVLCEVLKYNRKPAESNLRHSCQKIMSMIANEYPWFGMEQEYTLLGTDGHPFGWPSNCFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIELSGTNAEVMAAQWEYQVGPCEGIQMGDHLWISRFILHRVCEDFGIIASFDPKPIPGNWNGAGCHTNFSTKAMRDDGGLKYIEDSIEKLGKRHQYHIRAYDPKGGLDNARALTGHHETSNINEFSAGVANRGASIRIPRSVGQDKKGYFEDRRPSANCDPYAVTEALVRTCLLDESGDKPIEYNKN
What is the function of this protein?
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine.
What are the official names of this protein?
Glutamine synthetase, mitochondrial, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
[Isoform Mitochondrial]: Mitochondrion. SUBCELLULAR LOCATION: [Isoform Cytoplasmic]: Cytoplasm.
Protein: SERC_BORPE
Sequence: MMARPWNFSAGPSALPEAVLQQAAAEMLDWHGSGMSVMEMSHRGKHFVQICDEAEADLRELLGLPADYAVMFMQGGGLGENAIVPMNLMGRRSTPAADFVVTGHWSTRSHKEAGRYGDAQIAASAAEATEIDGQAQSSWTWLPPVDTWRVRKDSAYLHLCSNETIGGVEFTEWPDPASLGAPDVPLVVDVSSHFLSRPLDIARAGLVFAGAQKNAGPAGVTVVIARRDLLGHALPICPSAFDYANVAADHSRYNTPPTFAIYVMGLVFKWIKAHGGVRGMEEANRAKAELLYGYLDGSAFYRNPVQASVRSRMNVPFVLRDESLNDAFLQGAEAAGLMQLKGHKSVGGMRASIYNAMPLAGVQALIDYLKEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y05G_BPT4
Sequence: MKTVVKSYFGSHLYGTSTPESDVDFKEIFVPPARDILIGNVKEHMSKNTNNTSSKNTKDNIDHELYSLKYFFKLAADGEPVALDMLHTPPELVVKSDLPDVWKFIQDNRSRFYTTNMKSYLGYVRKQASKYGVKGSRLAALRDVLKVVNQIPEQWVDYQEDGSIKQRRTKVEDIKHRLPENEFCEWVFHNHEKTGPQTFYTVLGRKYQTTLSLIELKQSLNKLDAEYGERARKAEANEGIDWKALSHACRGGLQLLEIYKTGDLVYPLQDAPFILDVKLGKHPFKTVQEFLEDVVDQVEAASTEASKNGMQQKVDMSFWDDFLERVYLENHRSYYK
What are the official names of this protein?
Uncharacterized 38.9 kDa protein in nrdC-mobD intergenic region.
Protein: PSB28_PROMP
Sequence: MAENNLAKIQFYEGTDEPVVPEIRLTRGNDGTTGQAIFIFEKPQALSSVADGEITGMRMIDAEGEILTREVKVKFVDGEPMFLEGTYIWKTKSDFDRFMRFANSYAKSNGLGYSEKK
What are the official names of this protein?
Photosystem II reaction center Psb28 protein, Photosystem II 13 kDa protein, Photosystem II reaction center W protein.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: TRMFO_DICTD
Sequence: MEKVKIIGGGLAGSEAAWQLAKRKIPVEIYEMRPIVTTPVHKTEYLAELVCSNSFKSTEITNASGLLKEEMRKLDSLLLRVAEETRVPAGVALAVDRELFSKRVQEILLESPYVTVIREEVKKLPKEGIVIVATGPLTSSDFAEHLMEVLDTDSLYFYDAVSPIIYADSINYEKVFSASRYGKGEETYLNCPMTKEEYERFVEELINAETVESHYPGEEKFFEGCLPIEVLAKRGIDTLRYGPMKPIGLIDPKTGKEPYAVVQLRPENIQKTLYSMVGFQTRLKFQEQRRIFRMIPGLENAEFARYGVMHRNTYFYAPKFLKATLQFIKDERVFFAGQLIGVEGYMESAAMGIVAGINAARLYKGKPLIILPPTTMIGALISYVTTKVPVRYYQPMNANWGILLPLDKPIKDKKLRNRLLAERALRDLEDVIRRFAINV
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_CLOK1
Sequence: MPKMKTKKSVAKRFKLTGTGKLKRAQAFKSHILTKKSRKTKRNLRKTAYVSETQEKVMKKLLPYV
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: EXOA_STRPN
Sequence: MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQETKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEIGAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEKPVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPERYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL
What is the function of this protein?
In addition to 3'- to 5'-exonuclease and 3'-phosphatase activities, ExoA was shown to make single-strand breaks at apurinic sites in DNA.
What are the official names of this protein?
Exodeoxyribonuclease.
What is the protein family that this protein belongs to?
Belongs to the DNA repair enzymes AP/ExoA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACEA_COREF
Sequence: MSNVGTPRTAQEIQQDWDTNPRWNGITRDYTAEQVAELQGSVVEEHTLAKRGAEILWDAVSAEGDDYINALGALTGNQAVQQVRAGLKAVYLSGWQVAGDANLAGHTYPDQSLYPANSVPNVVRRINNALLRADEIARVEGDTSVDNWLVPIVADGEAGFGGALNVYELQKGMITAGAAGTHWEDQLASEKKCGHLGGKVLIPTQQHIRTLNSARLAADVANTPTVVIARTDAEAATLITSDVDERDRPFITGERTAEGYYHVKPGLEPCIARAKSYAPYADMIWMETGTPDLELAKKFAEGVRSEFPDQLLSYNCSPSFNWSAHLEADEIAKFQKELGAMGFKFQFITLAGFHSLNYGMFDLAYGYAREGMPAFVDLQNREFKAAEERGFTAVKHQREVGAGYFDTIATTVDPNSSTTALKGSTEEGQFH
What is the function of this protein?
Involved in the metabolic adaptation in response to environmental changes.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: BAF_DROME
Sequence: MSGTSQKHRNFVAEPMGNKSVTELAGIGETLGGRLKDAGFDMAYTVLGQYLVLKKDEELFKDWMKEVCHASSKQASDCYNCLNDWCEEFL
What is the function of this protein?
Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development.  May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly.  Functions are required in both M phase and interphase of the cell cycle.
What are the official names of this protein?
Barrier-to-autointegration factor.
What is the protein family that this protein belongs to?
Belongs to the BAF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=Colocalizes with chromosomes during both interphase and mitosis.
Protein: SIHH_METMA
Sequence: MTEKELIESGNMKMEWARNHMPVLAIIREKFEKEKPLKGLKVGMALHVEAKTAVLVETLAAGGAQVAISGCNPLSTQDDVAAALDTRENINCFAKYGCCTGEYYEAIDRVLDIEPDITIDDGADLIFKLHKERQEMLAKILGGCEETTTGVHRLHAMEKDGALKMPVIAVNDAMTKYLFDNRYGTGQSAWDGINRTTNLLVAGKNVVVAGYGWCGRGVAMRATGLGASVIVTEIDPIRALEARMDGHRVMKMSEAAKIGDLFVTATGNRDILTADNFKVMKDGAILANSGHFNVEIDMEALDSLAKSTRTVRHNIKEYDIGNRRINVIAEGRLVNLAAGDGHPAEVMDMSFANQALCVRYIAENKLSSGVHGVPRELDTYVAKLKLESMGIATDELTSKQECYMSGWECGT
What is the function of this protein?
Catalyzes the hydrolysis of S-inosyl-L-homocysteine (SIH) to L-homocysteine (Hcy) and inosine.  Likely functions in a S-adenosyl-L-methionine (SAM) recycling pathway from S-adenosyl-L-homocysteine (SAH) produced from SAM-dependent methylation reactions.  Can also catalyze the reverse reaction in vitro, i. e.  the synthesis of SIH from Hcy and inosine.
What are the official names of this protein?
S-inosyl-L-homocysteine hydrolase, SIHH.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIGA1_HUMAN
Sequence: MSDCCSAPGISWEAGVGRPAVPGLELQIRRGAMSEETVSESQFSLKTAALRVFDLPLTWYYSLSQIKFSPVAKKLFVVTAVSAISVIFLAHHFKRKRGKKKGKILPWEPEHLILEYTKRAASDKGSSCSSSRQNLTLSLSSTKDKGSQVCNYANGGLFSKYSGSAQSLASVQSVNSCHSCACGNSNSWDKADEDDIKLVNIPVTTPENLYLMGMELFEEALRRWEQALTFRNRQAEDEACGSIKLGAGDAIAEENVDDIISTEFIHKLEALLQRAYRLQEEFEATLGASDPNSLADDIDKDTDITMKGNVEDFGLRDTLSIASTDSFASAAELAEHREVRHTYSLESLCHCPFYEEAMHLVEEGKIYSRVLRTEMLECLGDSDFLAKLHCIRQAFQVILSESANRIFLAESGRKILSALIVKARKNPKKFEDVFDEMIYFLEQTDHWGSTEMELAARGVKNLNFYDVVLDFILMDSFEDLENPPTSIQNVVNNRWLNSSFKETAVASSCWSVLKQKRQQMKIPDGFFAHFYAICEHISPVLAWGFLGPRNSLYDLCCFFKNQVLLFLKDIFDFEKVRYSSTETLAEDLMQLLIRRTELLMAYLEADALRHTSSCLSSHGHVMSTGLLEAKVQ
What is the function of this protein?
Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers.  May act by regulating phospholipid metabolism via PLD6/MitoPLD.
What are the official names of this protein?
Mitoguardin 1, Protein FAM73A.
What is the protein family that this protein belongs to?
Belongs to the mitoguardin family.
Protein: RPOB_BURO1
Sequence: MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADVPATQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYALSSPAFNIKECQQRGLTYCSALRAKVRLVILDKESPNKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMDEGAQLEFVPERLRGEVARFDITDRDGKVIVQKDKRINAKHIRDLEAAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIASANDEVTESVLEKLREAGIKDIQTLYTNDLDQGPYISSTLRVDETTDKTAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEEAYDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYMIAQANAAIDENGQLIDELVSSREAGETMMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTCAVDSGTTVQAFRGGVVDYVDAGRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPIVKMGDKVSRGDVLADGASTDLGELALGQNMLIAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLARMLVGKVANGGPKKLAKGTKIDQAYLEDLDHYHWFDIRLADDEAAAQLEAIKNSIEEKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIEELRTFLTKIYNESGRQEDLESFTDDEILELAKNLREGVPFATPVFDGATEEEMGKMLDLAFPDDIAEQLGMNPSKNQVRLYDGRTGEMFERRVTLGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ATGT_PYRFU
Sequence: MSRGDSMLRFEIKDRDAAGRIGKLEVNGKKIETPAIMPVVNPKQLIVEPKELKRMGFDIIITNSYIIYKDKKLREKALEKGIHRLLDYDGIIEVDSGSFQLMRYGKVEVTNREIVEFQHKIGVDIGTFLDIPTPPDAPREKAEQDLKITLERAKEAESIKQIPMNATVQGSTYLDLRKLAARKLSEMNFEIHPIGAVVPLLESYRFKDVVDIVIASKMGLRPDRPVHLFGAGHPMVFALAVAMGVDLFDSASYALYAKDDRYLTPQGTKRLEELEYFSCSCPVCSKYTPQELREMPKEEREKLLALHNLWVIREEINRVKQAIKEGELWRLVDERARAHPKLYAAYKRLLEYYHYLEEYEPITKKSAFFKISEESLKWPIARRAKERAEKVKAKFPESIPHPIFGEIPKYLSLTYPFAQSESEEDFQIEKPTRENAILYIMAIAEYQFGEGAGEAFRDAEVEIAKTGMPRQVKKNGKRLATVRAEDGLLTLGIEGAKRLHELLPYPVMRVVVNKEAEPFARKGKDVFAKFVEFADPKIRPYDEVLIVNENDELLATGQALLSGREMVLFSSGRAVKTRRGVEEKK
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: PRR12_HUMAN
Sequence: MDRNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVSTALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQSGEGSPEEGAVRLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTLYHSLHHYKYHTFLRCRDQTLAIEGGAEDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQAHSRCG
What are the official names of this protein?
Proline-rich protein 12.
What are the subcellular locations of this protein?
Nucleus. Postsynaptic density. Synapse, synaptosome.
Protein: GPA2_KLULA
Sequence: MGLCASKDSRESTHDGGPRVNRPGANDANRRNDVRKGAGDKKQDKKNKKAKGSIVNAASNINNSSSGKTKISTVSEDGTVSNGVGNTAEYDNANNKNNGNNNNSNNNDNNNNNNNNIGNNINGNNNNDSENIHDSNNSNIENKRYFNNINTGVLNGVNGNSTNSDKALSNQFDQSNNSETHSGTMTGISQALALNDSGVNGFDTDLAKRNGTVNASGGQSPGGSETVNALKVLLLGSGESGKSTVLQQLKILHQNGFSREELLEYKPFIFDNIIETGKDLAKARRTFNVQLEEDAEISESDLDELLSQQYQPTKLPCLPADLAKTLKILWNLQSTQDLLVSEHRSSFYLMDSASYFYENLDRISEPKYIPTITDVIRTRKKTSGIFDTMIDLDKNLKLHFFDVGGQRSERKKWIHCFDNVTLIIFCVSLSEYDQTLLEDNSQNRLEESLILFDSVVNSRWFARSSVVLFLNKIDIFAEKLRHVPLEKYFPDYTGGKDINKAAKYILWRFVQLNRANLNIYPHVTQATDTSNIKLVFAAIKETILENSLKDSGVL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  This protein may be involved in the determination of the cAMP level according to nutritional conditions, most probably as a regulator of adenylyl cyclase.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-2 subunit, GP2-alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.