PharMolix/UniProtQA huggingface dataset:
Protein: LNT_AGRFC
Sequence: MERLAGRVMLAGGMSRAVMAIAAGAVGALALPPFGFFAALFFSFTLLVWLVDGCTGKPGGGLFSRILPAFGIGWCFGFGYFVAGLWWLGNALLLEADEFAWALPLAILGLPALLALFYGFAVAAANLLWSDGLGRIAALAAAFGVSEWLRSFLATGFPWNAIGYGIMPIPIMMQSAHLLGLLSITTLAVFIFASPALIGTKKGMGPGLALAGLLLAAHFGYGFYRLQTPAETPADALTVRIVQPAIDQSRKMLNTDRAEIFAEHLRLSALPPGEGKKRPDIIVWPETSVPFILTQNPDALAEIASTLEDGQVLFTGAVRMEDQGAGRPPRYYNSVYAIDSQGEIIGATDKVHLTPFGEYVPFEGILREFGIDNVIALPGGFSAASSRTPLTLPSGKTFYPLICYEIIFPGEMTPGLQGAAAILNVTNDGWFGDTPGPYQHFLQARVRAVETGVPVIRGANTGISAVIDPYGRIIAGLDYGRVGILDATLSGGSNDAFTYDTHRTYFWLIFSILMIVAVFPALSFARRQN
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y3385_CAUVC
Sequence: MLMVISPAKSLDFTAPQTVLPLTTPELKAQIAELSKVTRKLTAADLKRLMHISDALATLNRERFQAFDPEVEEGLQAVIAFNGDVYAGLNARELDRPALEWAQDHLRILSGLYGVLRPFDALQPYRLEMGTRLKTKKGANLYDFWGETISRTLNQAAEGHADPTLVNLASQEYFGAVDAKALKLPVVTCHFKEEKGGELRVLGFFAKKARGRMARYIIDNRIDQAEALKGFDLDGYRFQPGLSTSADWVFARPQP
What are the official names of this protein?
UPF0246 protein CC_3385.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: PSBI_CHLSC
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CH10_BACC3
Sequence: MLKPLGDRVVIELVQAEEKTASGIVLPDTAKEKPQEGKVIAVGTGRVLENGERVALEVAAGDLIIFSKYAGTEVKYEGTDYLILRESDILAVIG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_HAEI8
Sequence: MAENQNYGTGRRKSSSARVFIKPGSGKITINQRELDVYFGRETARMVVRQPLELVELTDKLDLYITVKGGGISGQAGAIRHGITRALMEYDETLRPALRAAGFVTRDARRVERKKVGLHKARRRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: SPEA_STRP8
Sequence: MENNKKVLKKMVFFVLVTFLGLTISQEVFAQQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNVSGPNYDKLKTELKNQEMATLFKDKNVDIYGVEYYHLCYLCENAERSACIYGGVTNHEGNHLEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVRKYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYKDNETLDSNTSQIEVYLTTK
What is the function of this protein?
Causative agent of the symptoms associated with scarlet fever, have been associated with streptococcal toxic shock-like disease and may play a role in the early events of rheumatic fever.
What are the official names of this protein?
Exotoxin type A, Erythrogenic toxin, SPE A, Scarlet fever toxin.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
Protein: YTZG_BACSU
Sequence: MRLDKLLANSGYGSRKEVKAVVKAGAVMIDGKPAKDVKEHVDPDTQEVTVYGEPVDYREFIYLMMNKPQGVLSATEDSRQQTVVDLLTPEEMRFEPFPAGRLDKDTEGFLLLTNDGQLAHRLLSPKKHVPKTYEVHLKSQISREDISDLETGVYIEGGYKTKPAKAEIKTNDSGNTVIYLTITEGKYHQVKQMAKAVGNEVVYLKRLSMGRVSLDPALAPGEYRELTEEELHLLNEPQA
What are the official names of this protein?
Uncharacterized RNA pseudouridine synthase YtzG, RNA pseudouridylate synthase, RNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: FENR_NOSS1
Sequence: MSNQGAFDGAANVESGSRVFVYEVVGMRQNEETDQTNYPIRKSGSVFIRVPYNRMNQEMQRITRLGGKIVSIQTVSALQQLNGRTTIATVTDASSEIAKSEGNGKATPVKTDSGAKGFAKPPAEEQLKKKDNKGNTMTQAKAKHADVPVNLYRPNAPFIGKVISNEPLVKEGGIGIVQHIKFDLTGGNLKYIEGQSIGIIPPGVDKNGKPEKLRLYSIASTRHGDDVDDKTISLCVRQLEYKHPESGETVYGVCSTYLTHIEPGSEVKITGPVGKEMLLPDDPEANVIMLATGTGIAPMRTYLWRMFKDAERAANPEYQFKGFSWLVFGVPTTPNILYKEELEEIQQKYPDNFRLTYAISREQKNPQGGRMYIQDRVAEHADELWQLIKNEKTHTYICGLRGMEEGIDAALSAAAAKEGVTWSDYQKDLKKAGRWHVETY
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes.
Protein: CLA3_CLACD
Sequence: MHNGSESVLLFGDYTEPWIESIDSLCRQAVSEAWLQSFLDDTVTIIKEQKRSIERILQDSLGEFTDLKDLADRHRGRTDEISYVQGLMLFTVRAAYLLQWVKRDPSLLTASHAIGFSGGLANASVLAVAQDFDTLYTACLEGLRIFSRSCRLAIVRSRAIEEGSGSWGWLVVGISSNDLRHALDHFQNSLGIPNSKRSKVGLTGDRWNTVIGPPSTLELVFKQCPAIKSLPKEKLNIHALQHALDLSESDLDYIIGDSALAQSHVNPEFSLWGMAQPKEPWGSWGELLKVVIVKMLSEPLDIVGVVDEFSGRLGSVPQVNICNMAMEGPSSHAAYLLSTMKLSGKTVNFENGFGSEKAQSASSGRIAIVGMSGRGPGCEDLEEFWNVISNAQDQHQEIPKDRFNLEDYLKQGHVTHCQSESMAKHGCFITKPGEFDARFFHISPREALLMDPGHRMFLMSAYEALETAGYSNGHTKATDPQKISIFFAQCNDDWRIASHDVKGCDSYTLPGTARAFGPGRLAFHLGWEGPAYSMDSACASSVSSVHFACMSLKNKDTDMAVVGAANVIGYPHTFISLSQSGVLSRTGNCKPFRDDADGYCRADFSGAIVLKRLEDAIAANDNILGVLAGTGRNQAGNATSITTSDTATQTRLFHKVLRSANVSPEDISYVEMHGTGTPIGDPAEMGAIANVFGNRKGNTPLPLGAVKGNVGHSESSAGMASLLKCLMMLQKDAIPPQAGMPHALNPKFPSLSDINVVIPSKLGDFKKTLNMPRRILLNNFDAAGGNGCLLLEEYVPPTSKELNIDEQDPRSTHVVVLSAKTQASHHANKRNLLDWLKTNRSTRIQDIAYTSTARRVHWPLRYAIAASSTQELTTKLESSIARENSESTNGRKSPIVFTFTGQGSQYAGMGAELYSTCFAFRDTIKLCARICDDHQFPDFIDIITDKDIDISTKSPLQIQLALLALEIGLAAFWKSIGVLPDMVVGHSLGEYAALYVAGVLSLGDVFYVVGRRAMLLLDRCEIGSCSMLALNASVATVQAHLDTQPHLSCAVACINGPKATVVSGPLGEIADLQTLFHGNKIRSKLLPVPFAFHSLQMEPILDEFTILAGIATFMQPKIPVASTLLATVVDKEGIFGTQYLAEQTRQRVDFVGALNAVKSKMDDPIWLEVGPSPVCSGLVQATISPSTTKIMSTLDATGSDWSSIAHCLSGLYQNGVDIDWLGLHAPYEGGLTLQALPSYQWDLKDYWMPYVEPSGVDQTVIANTASGRGTMSSSISTCAQYVITETKTPKPQVNLGAPTADAGFKAFIDGHRLRGVPVCAGAVFIEAAETAARYLLKYLGRNDADTAVLSLQDMALIRPITQKSVQANAELQTTATLDSGSKDTVRITFGESLAAGSSQHLGGCLLSICEAGLESQWEKSSFFIRSRMNDIIANVKGGQGHRIQRDIYYALFADTVEYDNPFRGVKEAYVSQDFEEAAAEVILKADPTGTQFTTSPYWTDSLSQLCGFVVNGNPSRPKDITYMMASLGSYIQMGQIVPGKSYFTYSRISDRAQDLVYCDTFVFDNDRLVAQSTNCVFHRVQNVILERLLGKPASSSVPAQASDPLRSKRSPQEARSLPGEAKTEKPGSTIATTSPVLESGKSEQGMFQALIAAIVKTTGGELSELNDDTELADIGVDSIMAIEIVAHVKDATNQDLPLSFVLEYPTIGNLRCAFDEDVSSEFTDSEVTSGTPNSSESVTSEEELPGPEEHAFKEPKDDSPLARRDMDNSNDRSLDGGVLDDGSPQPRVRISLLQGRPVRGKPKFFLIADGSGSIATYIHLPPAKVKMPIYGVDSPFLHCPSRFTPEAGIPAAAKWIVEALMKAQPEGPFFLGGFSGGAMLSYEVARQLAAFDRKVDSMVLIDMCCPRPAVSSDLKESLWNDDIESFEEIASHVGSNVASNMQQHLRAIFKAVSVYHPPSMTAKERPDRTIIIWAKKGMITRCHDVPEIMERLSARGLTRTIPEGFMEDPSFGAIRWSFVSKGANDLGPNGWQKYIGHEPLCLSVDLDHLEMMEPGQVHIFRGAFEEAFRLIEA
What is the function of this protein?
Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of cladosporin, a tricyclic octaketide that acts as an antimalarial agent though inhibition of the Plasmodium falciparum lysyl-tRNA synthetase (PubMed:26783060).  The highly reducing polyketide synthase cla2 is responsible for biosynthesis up to the pentaketide stage, including of the tetrahydropyran (THP) ring, whereas the three subsequent ketide extensions with no reduction are catalyzed by the non-reducing polyketide synthase cla3 (PubMed:26783060).
What are the official names of this protein?
Non-reducing polyketide synthase cla3, Cladosporin biosynthesis cluster protein 3.
Protein: NU2C_ADICA
Sequence: MNDINLFLAKLTYTSAKLTILPEIILILGLVAVVVIDLLSKGKNTFLLYKISMVTLLASAVILLWQWGFFTAYERSHARDFGNIFRFFLLICSLLSISSSVDYILCSKMSLAEFLLFKLAAGLGGMVLSCANDLVTIYVSLEFLALSSCFLSGYTKRDMRSNEATMKFLLMSGASSSLLLYGFSLLYGLSGGQLQLDKIVDGIIFNRYGSIIYLSAAFTTAGTAFKLSLFPFHQWTPDVYEGSPTPVVAFFSVTSKVAALALFTRLFGLIFPYFSNEWHVAVGLLATFSMILGNLIAVTQRSVKRMLAFSSISQIGYIMIGVLSADSGNGYASMITYTFIYILMNLGTFACITLFGLRTGTDNIRDYAGLYMKDPVLTFSLVLCLLSLGGMPPLSGFFGKLYLFWHGWKAGLYSLVLVALVTSVISIYYYLKIIKLMFTGKSGRSDTPLNSRQNSLVSLSISISKNSLEIAMIICALASTLSGIFIDPIIEITRNTFF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic, NAD(P)H dehydrogenase, subunit 2, NADH-plastoquinone oxidoreductase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: UBP28_RAT
Sequence: MTAELQQDDAAGAADGHGSSCQMLLNQLREITGIQDPSFLHEALKASNGDITQAVSLLTDQRVKEPSHDTAATEPSEVEESATSKDLLAKVIDLTHDNKDDLQAAIALSLLESPNIQTDSRDLNRIHEANSAETKRSKRKRCEVWGENHNPNNWRRVDGWPVGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSYSLPQNILENCRSHTEKRNIMFMQELQYLFALLLGSNRKFVDPSAALDLLKGAFRSSEEQQQDVSEFTHKLLDWLEDAFQLAVNVNSNPRTKSENPMVQLFYGTFLTEGVREGKPFCNNETFGQYPLQVNGYHNLDECLEGAMVEGDIALLPSDRSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQVIYMDRYMYKSKELIRSKRESIRKLKEEIQVLQQKLERYVKYGSGPSRFPLPDMLKYVIEFASTKPASESCLSGSVEHMTLPLPSVHCPISDLTAKESSSPKSCSQNAEGSFSSPEDALPNSEVMNGPFTSPHSSLEMPAPPPAPRTVTDEEMNFVKTCLQRWRSEIEQDIQDLKNCISSTTQAIEQMYCDPLLRQVPYRLHAVLVHEGQASAGHYWAYIYNQPRQIWLKYNDISVTESSWEELERDSYGGLRNVSAYCLMYINDKLPHCSAEAAHGESDQTAEVEALSVELRQYIQEDNWRFEQEVEEWEEEQSCKIPQMESSPNSSSQDFSTSQESSAASSHGVRCLSSEHAVIAKEQTAQAIANTAHAYEKSGVEAALSEVMLSPAMQGVLLAIAKARQTFDRDGSEAGLIKAFHEEYSRLYQLAKETPTSHSDPRLQHVLVYFFQNEAPKRVVERTLLEQFADRNLSYDERSISIMKVAQAKLMEIGPEDMNMEEYKRWHEDYSLFRKVSVYLLTGLELFQKGKYQEALSYLVYAYQSNAGLLVKGPRRGVKESVIALYRRKCLLELNAKAASLFETNDDHSVTEGINVMNELIIPCIHLIINNDISKDDLDAIEVMRNHWCSYLGKDIAENLQLCLGEFLPRLLDPSAEIIVLKEPPTIRPNSPYDLCSRFAAVMESIQGVSTVTVK
What is the function of this protein?
Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability.  Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN.  Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C).  In contrast, it does not deubiquitinate PLK1.  Specifically deubiquitinates MYC in the nucleoplasm, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with FBXW7 (FBW7alpha) in the nucleoplasm and counteracting ubiquitination of MYC by the SCF(FBXW7) complex.  Deubiquitinates ZNF304, hence preventing ZNF304 degradation by the proteasome and leading to the activated KRAS-mediated promoter hypermethylation and transcriptional silencing of tumor suppressor genes (TSGs) in a subset of colorectal cancers (CRC) cells.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 28, Deubiquitinating enzyme 28, Ubiquitin thioesterase 28, Ubiquitin-specific-processing protease 28.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP28 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: ARR19_ARATH
Sequence: MLVGKISGYEDNTRSLERETSEITSLLSQFPGNTNVLVVDTNFTTLLNMKQIMKQYAYQVSIETDAEKALAFLTSCKHEINIVIWDFHMPGIDGLQALKSITSKLDLPVVIMSDDNQTESVMKATFYGACDYVVKPVKEEVMANIWQHIVRKRLIFKPDVAPPKPRMTWSEVFQPVQSHLVPTDGLDRDHFDSITINGGNGIQNMEKKQGKKPRKPRMTWTEELHQKFLEAIEIIGGIEKANPKVLVECLQEMRIEGITRSNVASHLQKHRINLEENQIPQQTQGNGWATAYGTLAPSLQGSDNVNTTIPSYLMNGPATLNQIQQNQYQNGFLTMNNNQIITNPPPPLPYLDHHHQQQHQSSPQFNYLMNNEELLQASGLSATDLELTYPSLPYDPQEYLINGYNYN
What is the function of this protein?
Putative transcriptional activator that binds specifically to the DNA sequence 5'-[AG]GATT-3'.  Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  Could directly activate some type-A response regulators in response to cytokinins (By similarity).
What are the official names of this protein?
Putative two-component response regulator ARR19.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: WRK62_ORYSJ
Sequence: MDDDGDGSSSPTDDSAAAGLLPLFSRSPAEDLEEKLRRAMEENARLTRALDAILAGHHAHQRALLAPSLSPPPPSATARAPSVSTSCAAREDAAPAVAAAAASTACPSRQQPPTAEPRPKVRTVRVRADAADATDANSMAETVKDGYQWRKYGQKVTRDNPYPRAYFRCAFAPSCPVKKKLQRCAEDRSMLVATYEGEHNHALSTQTTEFVASGCTTSQHAGGSSSSPLPCSISINSSGRTITLDLTNQAGSGSIASCGVEAAAVSGELVTVLSPELRRHLVEEVVQVLKNDAEFVEAVTNAVAARVVDQIPHIPVHL
What is the function of this protein?
Transcription repressor.  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.  Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity).  Regulates negatively basal innate immunity and XA21-mediated defense against X. oryzae pv.  oryzae (Xoo) (PubMed:19825552, PubMed:21961049).
What are the official names of this protein?
WRKY transcription factor WRKY62, OsWRKY62, XA21-binding protein 10.
What is the protein family that this protein belongs to?
Belongs to the WRKY group II-a family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TYSY_MANSM
Sequence: MRQYLDLCQRIVNEGCWIENKRTGKRCLTVINADLTYDVANNRFPIITTRKSYWKAAIAEFLGYIRGYDNAADFRKLGAKTWDANANENQVWLNNPHRKGTDDMGRVYGVQGRAWRKPNGETVDQLRKIVNNLSRGIDDRGEILTFLNPGEFDLGCLRPCMYNHTFSLLGDTLYLTSYQRSCDVPLGLNFNQIQVFTFLALMAQITGKKAGQAYHKIVNAHIYEDQLELMRDVQLKREPFPSPKLEINPDIKTLEDLETWVTMDDFNVVGYQCHEPIKYPFSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_NOSP7
Sequence: MSKNLLEQLREVTVVVADTGDIQAIEKFKPQDATTNPSLITAAAQMPEYQGIVDQTLLQAKKDAGDGATQAQIVSLAFDRLAVAFGLKILQIIPGRVSTEVDARLSYDTEATLTKARDLIAQYKAAGIGRDRVLIKIASTWEGIRAAEILEKEGIHCNLTLLFGLHQAIACAEAGVTLISPFVGRILDWYKKDTGRDSYPATEDPGVLSVTKIYNYYKKFGYKTEVMGASFRNLGEITELAGSDLLTISPSLLAELQSTVAELPRKLDPAKAASLSIEKISIDKASYDKMHAADRMATDKLDEGIKGFTKALEDLEKLLADRLVRLEGEVVASH
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC52_CENOR
Sequence: KEDGYLVDKTGCKKSCYKLGENDYCNRECKWKHVGGSYGYCYGFGCYCEGLSDSTPTWPLPNKTC
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing (By similarity).  Not toxic to mice, chicks, crickets or woodlice (at 5ug) (PubMed:31734253).
What are the official names of this protein?
Toxin Co52.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GLO2_RHIME
Sequence: MAALELDLFLCRTDNYGVLLHDRLSGATASIDAPEERPILDALERRGWQLTHILTTHHHGDHVAANASLKERFGLTIIGPKNEASKIPGIDRTVGHGDRFDFAGHPVDVIETPGHTSGHVCYHLPEDKLLFAADTLFALGCGRLFEGTADTMWQSLSRLMALPDDTAIYFGHEYTLANAHFAITVDPENSALKERAAEIEETRSDGGFTAPTTMGLEKRTNPFLRAGDPKIRALLGMEKASDAAVFAEIRKRKDNF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: IF2_RHIE6
Sequence: MTDSNDDKTLSVTGKKTLTLKPSGMSQGTVRQDMGRGRTKAVVVETRKRRPMRPEDEKPITPAAPAAPVRAAEPAPAPVQARPPQPTPAPRVHQPGSSQANQRPQQSYQPQRSNDRPRPVVLNHLSPEEMDARRRALAESQARDAQDAIRRAEEEKRRAAEEAIRKAAEAEEAARRAAEEAARQAEAPAAAEPAVAAAPAPVVTEARPTAPRPASPAPAARRPDGAGAPAAARPAPGAGAPAGARGRRDDEGDDDRGAARGGPARGRVVRPEPAKPVTTRPKTDDERRRGKLTITTADVDGEDTGRSRSLSAMRRRQEKFRRSQMQETREKISREVVLPETITIQELSQRMSERAVDVIKFLMKEGQMMKPGDVIDADLAELIAGEFGHTVKRVSESDVELGIFNIADVEGDRVSRPPVVTIMGHVDHGKTSLLDAIRHANVVAGEAGGITQHIGAYQVEQNGQKITFIDTPGHAAFTAMRARGAQATDIAILVVAADDSVMPQTIESINHAKAAGVPIIVAINKIDKHEADPQKVRNQLLQHEVFVESMGGETLDVEVSAKTGKNLDKLLEAVLLQAEILDLKANPNRTAEGTVIEAQLDRGRGSVATVLVQNGTLKPGQIIVAGDVWGRVRALVTDKGDHVKEAGPATPVEVLGLSGTPQAGDKFAVVESESRAREISEYRQRLARDKAAARQSGQRGSLEQMMTQMQSTGIKEFPLVIKGDVQGSIEAIAGALEKLGTDEVRARIVHSGAGGITESDISLAEASNAAIIGFNVRANAQARQFAERQGIEIRYYNIIYDLVDDVKAAMSGLLSPERRETFIGNAEILEVFNITKVGKVAGCRVVEGKVERGAGVRLIRNDVVVHEGKLKTLKRFKDEVSEVPMGQECGMAFENYEDMRVGDVIECFRVEHITRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1719_STRMU
Sequence: MNTFLWILLVIIALLAGLVGGTFIARKQMEKYLEENPPLNEDVIRNMMSQMGQKPSEAKVQQVVRQMNKQQKAAKAKAKKKK
What are the official names of this protein?
UPF0154 protein SMU_1719c.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CSM4_MYCTO
Sequence: MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA
What is the function of this protein?
The subunit probably binds to the 5' handle of the crRNA, helping in discrimination between self- and non-self.
What are the official names of this protein?
CRISPR system Cms protein Csm4, CRISPR type III-A associated RAMP protein Csm4.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm4 family.
Protein: VRAR_STAAS
Sequence: MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
What is the function of this protein?
Member of the two-component regulatory system VraS/VraR involved in the control of the cell wall peptidoglycan biosynthesis.  Upon cellular stress, the histidine kinase VraS transfers the phosphoryl group onto VraR.  Upon phosphorylation, VraR dimerizes at the N-terminal domain.  In turn, phosphorylation-induced dimerization expands and enhances the VraR binding to its own promoter leading to increased expression and subsequent modulation of as many as 40 genes, which ultimately constitute the S. aureus response to cell wall damage (By similarity).  In addition, inhibits the host autophagic flux and delays the early stage of autophagosome formation, thereby promoting bacterial survival.  Facilitates the ability of S. aureus to resist host polymorphonuclear leukocytes-mediated phagocytosis and killing thus contributing to immune evasion (By similarity).
What are the official names of this protein?
Response regulator protein VraR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IAA3_ORYSJ
Sequence: MSPPLELDYIGLSPPPPPPSSSSAAAARADDVDLKGTELRLGLPGSESPDRRPAAIAAAAATATTLELLPAKGAKRVFPDEAALTPPTAAAGKGKAAREGEEVGAEEEDKKVAAPPQPAAKAQVVGWPPIRSYRKNTMATNQIKSNKEDVDAKQGQGFLYVKVSMDGAPYLRKVDLKTYKNYKDMSLGLEKMFIGFSTGKEGAENQKDGEYVLTYEDKDGDWMLVGDVPWEMFTDSCRRLRIMKGSDAIGLAPRAGEKSKNRN
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA3, Indoleacetic acid-induced protein 3.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSB1_SACS2
Sequence: MEELPATAVGLKVNDGIVLASERRLSYGGYVLSKQAKKVYKINKFLMAGAGIYGDLQTLTRIMNVEIKYYEVSTGKPISVHAAAKLLSVILYQYKVMPFISEILFGGVDEKGPQLYVLDPIGSLIEDNYAAVGSGARIAIGVLESEYDPNMSLDVATQLITKAIKASIERDITSGDGIDLAIIDKKGNYENKFIPY
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHR_ALOCA
Sequence: MPMQGAQRRLLGSLNSTPTATPNLGLAANHTGAPCLEVSIPHGLFLSLGLVSLVENVLVVAAIAKNRNLHSPMYCFICCLALSDLLVSGSNMLETAVILLLEAGALATRASVVQQLQNTIDVLTCSSMLCSLCFLGAIAVDRYVSIFYALRYHSIVTLPRARRAIAAIWVASVLSSTLFIAYCDHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGITRLHKRQLPAHQGFGLRGAATLTILLGIFFLCWGPFFLHLMLVVLCPQHLTCSCIFKNFKVFLTLIICNTIIDPLIYAFRSQELCRTLKEVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.