PharMolix/UniProtQA huggingface dataset:
Protein: RUXE_HUMAN
Sequence: MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:23246290, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346).  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (PubMed:15146077).  As part of the U7 snRNP it is involved in histone 3'-end processing (PubMed:12975319).
What are the official names of this protein?
Small nuclear ribonucleoprotein E, snRNP-E, Sm protein E, Sm-E, SmE.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: CYSH_ECO27
Sequence: MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEFB_DICDI
Sequence: MVVILWGWNENRFNTLDQVISFDFIEENKKLYLKILENEKQQKIYNISNLIGRRMDNYRDNNNNNGNGSNINNNGIIINSSMGSQYFNLNKGIIIVESDNETFLIEEIDYLGKFPILKQFIKCEEFIGISTLEIISNIEKQLSNLVNLKSNTTEQTDRKYKTNLIDFKESIIQLEKDCKNLLKQSNLINPSIKYSVVKSVKFLLKEIKFEFYHGDINIKRIELFQQLKKFLKIHFWNNPNLILNSGSNIDMTDSNDSISSEEINSPNDLNLSLSSFPSISSPSNSSYNNINTLTFSNNNNNNNNNSNNNNNNNNNNNNNNSIINSNNNNNSNNNSNISNSSNNNNNNSNNSNNISINVSKTGNNSVINSPTQSSSCYIDCDDTMSNYTDCTNTTNTNSTTTTTTTTTTYGNNLNVYNNNNNNNTNNNNNNVPYKKPALKMMKSPSFKIQLIQEVYLEIMDQCKKIQNYLYELLDTYLTDEEYINNNNNNNNKDISILFENNTSYCIAQEIFISLIKNSNDFLYQVQLIDLTDTRKKSKELSEVSNQLFYSTQQLFPSISDHLDFIEMDIFTNNNTTTTTTTTTTTTNTTTNPSNTIKSSHSSLLSSSYSSSKDDDIVLTINKVLSKLDTFSKEYTKLIGNNLSSNYYVDSGNNNESVSSPKCGLFLSHSLSTDSPMTYVKRNTSSGSSASTSSYTTPVSSSASLSFSSSTQTPSSAASQHHIQQILQQQQQQQQQQQQQQQQQQPQQIQSQSQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQIQSQSQQQQQLNRKPHYSSISPTSMLVYNATGGKFGVVNQNNNSAESTPTFQLNTMDILNSLMGKEGQNSNTNNANNPNNNNNNNNNNNNNNNNNNNNNNNNENKNENKNETNKSGHNYNNSSTSTLSSSTTIGDLANVSSTNSPNSSTPNLLLPPHQFHNHNREYNHSHHHLLSSSSNNVMINNRSIGKSFSTGNFSQPQPIMPSNGIGGSGGGGLGTTLSVGNGGIVGGLQSRSSSFEENQLQYAIESFMEVYNHLTSKDKVDTSIWLEEEKEDINVYYINNTNIDDKFYRSIKYASLNQLILKLTCESNTELRFTKTFITTYRSFTTGDIFLMKLIQRYFTPNLKNIVPYQFVQKIQIPIQLRVLNVLRLWIEQYPSDFQQPPQITTQSTQPIQNSTTQPQPQPQPQQPQPQLQQSTNLQNSTIQQPSLFKMLTAFLNSTRRNGHGQYSDLILKKFKQQKQKDRLQLPIINNGQGIPKAKIFWMKYSTEFIFSQSSTDIAEQLTLLDFDSYKSIEEIELLNQAWSKPDQKTNTPNIASMVNRFNSFSSFVSWAILRENDIKQRSKMMLKMIKICYALYKLSNFNGLLAGLSGLMASGVYRLNHTKSLISKQYQKKFDFLCKFLDTKKSHKVYRDIIHSTCPPLIPYLGIYLTDLTFIEDGNQDEIKGLINFKKREMIFNTILEIQQYQQQGYTIKPKPSVLGFLCELPHMSDKKKFEDDTYEQSILLEPKNSTKLEVMNAKK
What is the function of this protein?
Promotes the exchange of Ras-bound GDP by GTP (By similarity).  Involved in phagocytosis, fluid-phase endocytosis, regulation of macropinocytosis and control of cell movement.
What are the official names of this protein?
Ras guanine nucleotide exchange factor B, RasGEF domain-containing protein B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUD_ZYMMO
Sequence: MPTEQVTLTEEMIGWRLDRALASLITRLSRERLKNLISSGCVSNSQGALVRDPAFKIKSLDCFTVDIPLPRPAHNEPQDIPLEIVFEDEHLLVVNKPAGMVVHPAAGNYDNTLVNALLYHCAGKLSGIGGVARPGIVHRIDKDTSGLLVVAKTDPAHAGLAAQFADHSINRRYRAIVDGHPSLQGHVDAPLARSSVNRQKMAIVSDGRGKRAVTHYRMITPLKNASLIECRLETGRTHQVRVHMSSIGHSLLGDPVYGRSKKAHHALLQSLAFQRQALHAAHLGFIHPISGKQVDFDAEMPQDMQLLFKMLMISNRN
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: FEM1C_HUMAN
Sequence: MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLISEKTNGATPLLMAARYGHLDMVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLTNSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADVNRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKRDLLGALKYWKKAMNMRYSDRTNIISKPVPQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKALSIILHLICLLEKVPCTLEQDHFKKQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYPVCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHPDIMNLLIKSGAHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR
What is the function of this protein?
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C terminus of target proteins, leading to their ubiquitination and degradation (PubMed:29779948, PubMed:29775578, PubMed:33398170, PubMed:33398168).  The C-degron recognized by the DesCEND pathway is usually a motif of less than ten residues and can be present in full-length proteins, truncated proteins or proteolytically cleaved forms (PubMed:29779948, PubMed:29775578, PubMed:33398170, PubMed:33398168).  The CRL2(FEM1C) complex specifically recognizes proteins with an arginine at the C-terminus: recognizes and binds proteins ending with -Lys/Arg-Xaa-Arg and -Lys/Arg-Xaa-Xaa-Arg C-degrons, such as SIL1 or OR51B2, leading to their ubiquitination and degradation (PubMed:33398170, PubMed:33398168).  The CRL2(FEM1C) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding (PubMed:26138980).  Promotes ubiquitination and degradation of SLBP (PubMed:28118078).
What are the official names of this protein?
Protein fem-1 homolog C, FEM1c, FEM1-gamma.
What is the protein family that this protein belongs to?
Belongs to the fem-1 family.
Protein: SWT13_ARATH
Sequence: MALTNNLWAFVFGILGNIISFVVFLAPVPTFVRICKKKSTEGFQSLPYVSALFSAMLWIYYAMQKDGTAFLLITINAFGCVIETIYIVLFVSYANKKTRISTLKVLGLLNFLGFAAIVLVCELLTKGSTREKVLGGICVGFSVSVFAAPLSIMRVVVRTRSVEFMPFSLSLFLTISAVTWLFYGLAIKDFYVALPNVLGAFLGAVQMILYIIFKYYKTPVAQKTDKSKDVSDHSIDIAKLTTVIPGAVLDSAVHQPPALHNVPETKIQLTEVKSQNMTDPKDQINKDVQKQSQV
What is the function of this protein?
Mediates both low-affinity uptake and efflux of sugar across the plasma membrane.  Involved in nurturing the male gametophyte (PubMed:25988582).
What are the official names of this protein?
Bidirectional sugar transporter SWEET13, AtSWEET13, Protein SUGARS WILL EVENTUALLY BE EXPORTED TRANSPORTERS 13.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YOTI_BACSU
Sequence: MIEIFKDTGATHDLVYHSKINTFVWDVEFDIVLSDSKELNKCYFVKCFNPYRINGKCDFAVSSIDIFSEGKRLLIENEFNFKITKAVHVATSKDVTEIVLHLSERISSPFPIVKEVVYLD
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YotI.
Protein: PTHP_STAAS
Sequence: MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROCA_STAAW
Sequence: MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAADEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: RL36_BACAN
Sequence: MKVRPSVKPICEKCKVIRRRGKVMVICENPKHKQKQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ITB8_MOUSE
Sequence: MCGSALAFLTAALLSLHNCQRGPALVLGAAWVFSLVLGLGQSEHNRCGSANVVSCARCLQLGPECGWCVQEDFVSGGSGSERCDTVSSLISKGCPVDSIEYLSVHVVTSSENEINTQVTPGEVSVQLHPGAEANFMLKVRPLKKYPVDLYYLVDVSASMHNNIEKLNSVGNDLSKKMALYSRDFRLGFGSYVDKTVSPYISIHPERIHNQCSDYNLDCMPPHGYIHVLSLTENITEFEKAVHRQKISGNIDTPEGGFDAMLQAAVCESHIGWRKEAKRLLLVMTDQTSHLALDSKLAGIVVPNDGNCHLKNNVYVKSTTMEHPSLGQLSEKLIDNNINVIFAVQGKQFHWYKDLLPLLPGAIAGEIESKAANLNNLVVEAYKKIISEVKVQLENQVHGVHFNITAICPDGARKPGISGCGNVTSNDEVLFNVTVVMKTCDIMGGKNYAIIKPIGFNETTKVHIHRSCSCQCENHRGLKGQCAEAAPDPKCPQCDDSRCHFDEDQFPSETCKPQEDQPVCSGRGVCICGKCLCHKTKLGRVYGQYCEKDDFSCPYLHGDVCAGHGECEGGRCQCFSGWEGDRCQCPSASAQHCVNSKGQVCSGRGTCVCGRCECTDPRSIGRLCEHCPTCHLSCSENWNCLQCLHPHNLSQAALDQCKSSCAVMEQHRMDQTSECLSGPSYLRIFFIIFIVTFLIGLLKVLIIRQVILQWNNNKIKSSSDYRMSASKKDKLILQSVCTRAVTYRREKPEEIKMDISKLNAQEAFRCNF
What is the function of this protein?
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (By similarity).  It recognizes the sequence R-G-D in its ligands (By similarity).  Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (PubMed:25127859).  Required during vasculogenesis (PubMed:12050137, PubMed:16251442).
What are the official names of this protein?
Integrin beta-8.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: YB1D_SCHPO
Sequence: MRSNTFGSVMRISWVVAFITMVQTLVSGVPLTDNDLESEVSKGTWFIKYYLPSCGACKRLGPMWDNMVEKAKEQVEGSNFHFGEVDCSKELSSCANIRAVPTLYLYQNGEIVEEVPFGASTSEASLLDFVETHLNPDTDPDIPSDEDVLTDEDTEEVASIQPALSTSVSSLSLASTAMSKSASASEFSGSSVTKASKKLTSSPTSVASKKATLSSVSKVASTSSLPVTSVSASVDPKSAASKVQDAEFSIQTAPSFPKEKEEKENTEETEESKKSINPTGTSKALALDADIDAALTDKEGWFIQFYSSECDDCDDVSTAWYAMANRMRGKLNVAHINCAVSKRACKQYSIQYFPTFLFFKEEAFVEYVGLPNEGDLVSFAEEAANFEIREVELLDTVNAEKNGDVFFLYFYDDDSAEYLNIIRKTGIQLLGHANLYLTTSQQIAKKYRVVSFPKLIVVRDGIASYYPAKMAQDNKDYRRILGWMKNNWLPVLPELRTSNSKEIFNDESVVLFLLNPELDDFDETKRTAQKIATEFLDEEGRTYQSNWQKETDKKNSLVNEAEEKNDLEAIEAAKNFHVNGKPSPTRFAWVNGKFWAQWLRKFDIDIEATGPRVIVYNAAQDIYWDETAKGTPISIEKDTVFDIIKQVETDPDHLKFKILKKNLGVEYLESYGLNIRVLYMVLGIVTVGILVWYFSGRRARTLQRRRHSTPILPVSMRSTGNSGKFD
What are the official names of this protein?
Uncharacterized protein C3D6.13c.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ULAR_SHIDS
Sequence: MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGQEMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSSKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPETLQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_YERPN
Sequence: MQSYFNELEQVRYEGSQSTNPLAFHHYNPDEMILGKRMADHLRFAACYWHTFCWGGADMFGANAFDRPWQQPGDALALAKRKAEVAFEFFHKLNVPYYCFHDVDVSPEGASLQEYLNNFAVMTDVLAEKQAASGVKLLWGTANCFTHPRYGAGAATNPDPEVFSWAATQVFTAMNATRQLGGENYVLWGGREGYETLLNTDLRQEREQIGRFMQMVVEHKHKTGFQGTLLIEPKPQEPTKHQYDYDVATVYGFLKQFGLEKEIKVNIEANHATLAGHSFHHEIASAIALGIFGSVDANRGDPQLGWDTDQFPNSVEENTLVMFEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKFAAKMIEDGQLDQIVAKRYAGWNSELGQQILQGKMSLEELSRYASQHNLNPQHQSGHQELLENKVNRYLFG
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL27_BURP6
Sequence: MAHKKAGGSSRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTRMHAGENVGMGKDHTLFALVDGHVKFTTKGAAKKHTVVVVPAAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: UBC12_MOUSE
Sequence: MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK
What is the function of this protein?
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins.  The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4.  Involved in cell proliferation.
What are the official names of this protein?
NEDD8-conjugating enzyme Ubc12, NEDD8 carrier protein, Ubiquitin-conjugating enzyme E2 M.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.
Protein: Y961_NITOC
Sequence: MSRWKRRFLILGLSIVVLAVFLLIAGFEGIPFLVDLWWFSAQDYGFYFWQRALYQLVVFIQVSIVFFLIFFVNFWVASHYLGSERPADIPPGAPRKKFKNLFFRFQTGSLWIYTPLSLVLSIIIAWPLFQQWESFLLYLVAPDMGIQDPAYGKNISYYLFSFPIYVLILQRLLISFLLLLASLTLFYWIENRLLSQHGKRLPTGAKWHLSILVLMVFFIEIWDFFLQRNGLVYSEAHQPLFSGPGFVEMRVILPFIWLSMFFLLGIAFFLLLFIHKRKGLKTLAVFSLLFILSLGARHFHFLHWATQEYIVKPNELSIQKPFIENSIKATLDAYKLSNVEVRKFERKKALKNIFNAKVQDLLHNVPVWDKELVGQVYRQLQQLRTYYGFPAENVDRYMINGKKQQVFLGARELNYDKLPSGAQKWVNEHLLYTHGYGLAMSSAGQGQGEASMDWFIRGIPPESDEGFNIKQPGIYYGRGSYRYAIAPNENREFDYPKGNANVMTDYQGKGGVSLSSLFEKYIFSVYFQDKDIFFTTQTYDKSKILFRRNIIERIETLTPYLLLDAAPYLVATTEGLYWIQDAYTASTWYPNADVLGLMRFEFPIPPKGSEKINYIRNSVKIVVDAYHGTVNYYIFDSSDPIIQAYSRIYPGLFKPKEQMPEDIRAHIRYPKDLFEIQMGIYAKYHQTDLEIFYQQEDMWTFAQKYNRESETRLRPYYLTLDLIEENRLDFLLFLPMIVKGQDNMRAMLVAGSDDPYYGKLIAYSFPKGELVFGPAQINAVINEDPKVSAQFTLWNQDDSKVVLGDMIIMPVDQVILYIQPVFLTIKDDVRIPKLERIIISDGRSVVMEPTLMEAYAKLKERIETEGAEGESH
What are the official names of this protein?
UPF0182 protein Noc_0961.
What is the protein family that this protein belongs to?
Belongs to the UPF0182 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HIS4_AFIC5
Sequence: MEAVILFPAIDLKNGQCVRLEQGDMARATVFNLDPAAQARSFQDQGFEYLHVVDLDGAFAGKPQNAQAVEAMLKTVTMPVQLGGGIRDMATLQAWLDKGIARVIIGTAAVRDPAFVKEAAKKHPGRVAVGLDARDGKVAVEGWAETSTVTALEIAQRFEDAGVAAIIFTDIARDGLLKGLNLDATIALADAISIPVIASGGLASIDDVKALLTPRAKKLEGAISGRALYDGRIDPAEALALIKAARAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_BACAC
Sequence: MSLLIDFIDETEEVKEEYVNLIREILGKAAQMEKIEDGAELSVTFVDNERIREINRDYRDKDQPTDVISFAMEEMGEGEMEIVGVEMPRMLGDLIISIPRAKEQAEEYGHSFDRELGFLALHGFLHLLGYDHMTEEDEKEMFGRQKEILEAFGLGR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_BLOFL
Sequence: MHIIKTVLIRHGESQWNKDNRFTGWIDVDLSNQGYSEAKRAGQLLKKYKFIFDYGYTSVLKRTIHTLWVILDQLNQTWLPIQKVWQLNERHYGALQGLNKNEAIKTYGYDTIQKWRRSFKDIPPKNNKNDLFLGTNDIRYKNIETNTLPNGESLELTANRVIPYWQKYIEPKIYNNNCIIIVAHGNSIRAILKFLNQLDDSEIFNIEIPTGIPLIYEFDNNIKPIRYYYLSE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PHOSP_BEFVB
Sequence: MSHLKPKIMTGAYDAEKLRRNLQEQIALEEDELENQTDFESNKEESNINNNPLVIKQEPSIYPIEINLEDLEKANGMEEDWENSLMKIIESSDVTPKLSWNDEFENCTYKGYVVSSEDLCNDSGNQEKNEVPIKQSSLEDVAQVLSLFQIRSEVDYKIEKDNKNQVKIIKLSKQDKSVKSKRNDVVNQDSDKHMKYDSNFDAVMDQFQKGIRIKKRFGKGYVKINADNMPGTYHDLSNVISTVKGEKTVEEMIRYLFKKSKRFKSINKTLNIDEMILC
What is the function of this protein?
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication.  Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: ACCA_STRPI
Sequence: MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAVVGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRVWMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSSKELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKS18_MYCBO
Sequence: MNVSAESGAPRRAGQRHEVGLAQLPPAPPTTVAVIEGLATGTPRRVVNQSDAADRVAELFLDPGQRERIPRVYQKSRITTRRMAVDPLDAKFDVFRREPATIRDRMHLFYEHAVPLAVDVSKRALAGLPYRAAEIGLLVLATSTGFIAPGVDVAIVKELGLSPSISRVVVNFMGCAAAMNALGTATNYVRAHPAMKALVVCIELCSVNAVFADDINDVVIHSLFGDGCAALVIGASQVQEKLEPGKVVVRSSFSQLLDNTEDGIVLGVNHNGITCELSENLPGYIFSGVAPVVTEMLWDNGLQISDIDLWAIHPGGPKIIEQSVRSLGISAELAAQSWDVLARFGNMLSVSLIFVLETMVQQAESAKAISTGVAFAFGPGVTVEGMLFDIIRR
What is the function of this protein?
Involved in the biosynthesis of tri- and tetraketide alpha-pyrones.  Pks18 catalyzes the extension of medium- and long-chain aliphatic acyl-CoA substrates by using malonyl-CoA as an extender molecule to synthesize polyketide products.
What are the official names of this protein?
Alpha-pyrone synthesis polyketide synthase-like Pks18, Alpha-pyrone synthesis polyketide synthase type III Pks18, Chalcone synthase-like protein, CHS-like.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: GIA4_GIAIN
Sequence: MSATVSTVSADLHKAIDAGDEDKITKITASYGSEQRDKIIPAYHANYGIPPSEAIRKAFKTGFYETMIVHAWTSRFELRAKLIHESIKGKIDVITLLDLVIACMPDDWYGTKVCYTKLYGRELVREIDEVIGVGTPWQSLVSGWVKHDRKYRKSIKSDAEAFRMALDSDNYEVLGSMLATSVPDEWMRIAAAYEETTGMPIDQAIASRYVKVDQTALILAHHWLCDPGQAAAYICSQCCAERKGNYARICRFTSMMYDHCLKCKYAYRAYGSLAMDIRKCFEPKLAKHLLVFWRVE
What is the function of this protein?
Giardins are involved in parasite attachment to the intestinal mucosa and in the cytoskeletal disassembly and reassembly that marks the transition from infectious trophozoite to transmissible cyst.  They may interact with other cytoskeletal proteins such as microtubules in the microribbons or crossbridges, to maintain the integrity of the ventral disk (By similarity).
What are the official names of this protein?
Giardin subunit alpha-4.
What is the protein family that this protein belongs to?
Belongs to the annexin family. Giardin subunit alpha subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ALR_PSEF5
Sequence: MRPARALIDLQALRHNYQLARETSGVRALAVIKADAYGHGAVRCAQALEGEADGFAVACIEEALELRAAGIRAPVLLLEGFFEASELALIVEHDFWCVVHSLWQLEAIEQAAVAKPLTVWLKLDSGMHRVGLHPKDYQVAYQRLQASGKVEKIVLMSHFARADELDCPRSSEQVAVFEAARQGLGAEISLRNSPAVMGWPSVPSDWVRPGIMLYGSTPFEENNSVAARLQPVMTLESKVICVRELPAGEPVGYGARFITDRPMRIGVVAMGYADGYPRHAPTGTPVLVAGQRSRLLGRVSMDMLCVDLTDVPQAGLGSTVELWGKNILASDVAQAADTIPYQLFCNLRRVPLVYCEG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: CXG1_XENLA
Sequence: MSWSFLTRLLEEINNHSTFVGKIWLTVLIIFRIVLTAVGGESIYYDEQSKFTCNTHQPGCENVCYDAFAPLSHVRFWVFQIILITTPSIMYLGFAMHRIARQPDEQIRRLEKTKSKKRAPIIHRGAMRDYEEAEDNQEEDPMICEEEEPEKDSEKGDKKKHDGRRRIKQDGLMKVYVLQLLFRSVFEVGFLMGQYVLYGFEVIPFFVCSRNPCPHTVDCFVSRPTEKTIFLLIMYAVSALCLFLNLCELFHLGIGGIRDALRQKRKEIQESRKKKPSAPPNYHSVLKKGKLPNGKPVFPGNGVSEGFEMPVHELDRLRQHLKLAQEHLDLAFHLNPSADIAHASRSSSPEANSIAAEQNRLNLAQEKGVGSREKSGL
What is the function of this protein?
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
What are the official names of this protein?
Gap junction gamma-1 protein, Gap junction alpha-7 protein.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Gamma-type subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: NUOB_XANOM
Sequence: MGVIQTLDRLMTNPMPEGRVEDILRPEGENPLLEKGYVTTSVDALLNWARTGSMWPMTFGLACCAVEMMHAGASRLDLDRYGVVFRPSPRQSDVMIVAGTLVNKMAPALRKVYDQMPDPKWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALVYGILQLQKKIWRTQTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.