PharMolix/UniProtQA huggingface dataset:
Protein: HH_DROVI
Sequence: MDNQTVAAIWSCASATCLSLDAKRHSVETNTNDRQAPPGLSNSNNNNNNNKSTAVDADPRKLRHIAHTPRGSCFMALLLLLLLALNFRHAHSCGPGRGLGRRRERNLYPLVLKQTVPNLSEYMSGASGPIEGVIQRDSPNFKDLVPNYNRDIIFRDEEGTGADRLMSKRCREKLNTLSYSVMNEWPGVRLLVTESWDEDHQHGQESLHYEGRAVTIATSDRDQSKYGMLARLAVEAGFDWVSYVSRRHIYCSVKSDSSPFISHVHGCFTPESTALLESGAKKPLSELAIGDRVLSMNGKGQAVYSEVILFMDRNLEQMQNFVQLHTDSGAVLTVTPAHLITVWQPEREALDFVFADRVEELNYVLVHDATGELRPHRVIRVSSVRSRGVVAPLTREGTIVVDSVAASCYAVISSQSLAHWGLAPMRLLYTLQSWMPAKGQLRTAQDKSTPKDATAQQQNGLHWYANALYKVKDYVLPQSWRHD
What is the function of this protein?
The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.  Establishes the anterior-posterior axis of the embryonic segments and patterns the larval imaginal disks.  Binds to the patched (ptc) receptor, which functions in association with smoothened (smo), to activate the transcription of target genes wingless (wg), decapentaplegic (dpp) and ptc.  In the absence of hh, ptc represses the constitutive signaling activity of smo through fused (fu).  Essential component of a signaling pathway which regulates the Duox-dependent gut immune response to bacterial uracil; required to activate Cad99C-dependent endosome formation, norpA-dependent Ca2+ mobilization and p38 MAPK, which are essential steps in the Duox-dependent production of reactive oxygen species (ROS) in response to intestinal bacterial infection.  During photoreceptor differentiation, it up-regulates transcription of Ubr3, which in turn promotes the hh-signaling pathway by mediating the ubiquitination and degradation of cos.
What are the official names of this protein?
Protein hedgehog.
What is the protein family that this protein belongs to?
Belongs to the hedgehog family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear up to embryonic stage 10 and then at stage 11 shifts to the cytoplasm. Also secreted in either cleaved or uncleaved form to mediate signaling to other cells. SUBCELLULAR LOCATION: [Protein hedgehog N-product]: Cell membrane; Lipid-anchor. Note=The N-terminal peptide remains associated with the cell surface. Heparan sulfate proteoglycans of the extracellular matrix play an essential role in diffusion. Lipophorin is required for diffusion, probably by acting as vehicle for its movement, explaining how it can spread over long distances despite its lipidation.
Protein: RL17_PARL1
Sequence: MRHGNSGRKLNRTASHRKAMFANMAIALIKHEQIVTTLPKAKELRPYVEKLITLGKRGDLHARRQAYAALPDKVWAAKLFDVLGPRYQERQGGYIRVLKAGFRHGDSAPMAVIEFVDRDESAKGQDSGPVHVEGDEEAA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: AAEX_ECOLI
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMG_BURMA
Sequence: MTVQQRRRPPIASRETLQALLSEGAQALGVALSDAQRGALLDYVALLAKWNAVYNLTAIRDPRQMLIQHILDSLSIVPHLGAHGAAAAALDVGSGGGLPGVVLAIALPGWRVTLNDIVHKKSAFQNQAKAELKLGNLSVVTGRVETLRPGADVPAKFDVIVSRAFADLADFVTLARHLVAPGGSIWAMKGVRPDEEIGRLPDGARVKQMIRLTVPSLDAERHLIEVELDEAI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP33A_HUMAN
Sequence: MAAHLSYGRVNLNVLREAVRRELREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVEKMFTLKGNRLPAADVKNIIFFVRPRLELMDIIAENVLSEDRRGPTRDFHILFVPRRSLLCEQRLKDLGVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEGDQTSLYHAAKGLMTLQALYGTIPQIFGKGECARQVANMMIRMKREFTGSQNSIFPVFDNLLLLDRNVDLLTPLATQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGDGGKDLPTEAKKLQLNSAEELYAEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVGEIKQFVSQLPHMQAARGSLANHTSIAELIKDVTTSEDFFDKLTVEQEFMSGIDTDKVNNYIEDCIAQKHSLIKVLRLVCLQSVCNSGLKQKVLDYYKREILQTYGYEHILTLHNLEKAGLLKPQTGGRNNYPTIRKTLRLWMDDVNEQNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQPLPTGLQKKRQPGENRVTLIFFLGGVTFAEIAALRFLSQLEDGGTEYVIATTKLMNGTSWIEALMEKPF
What is the function of this protein?
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways.  Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion.  The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes.  The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203).  Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS16 but not VIPAS39 (PubMed:25783203).  The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG (PubMed:24554770).
What are the official names of this protein?
Vacuolar protein sorting-associated protein 33A, hVPS33A.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle, clathrin-coated vesicle.
Protein: G3P_HOMAM
Sequence: SKIGINGFGRIGRLVLRAALSCGAQVVAVNDPFIALEYMVYMFKYDSTHGVFKGEVKMEDGALVVDGKKITVFNEMKPENIPWSKAGAEYIVESTGVFTTIEKASAHFKGGAKKVVISAPSADAPMFVCGVNLEKYSKDMTVVSNASCTTNCLAPVAKVLHENFEIVEGLMTTVHAVTATQKTVDGPSAKDWRGGRGAAQNIIPSSTGAAKAVGKVIPELDGKLTGMAFRVPTPDVSVVDLTVRLGKECSYDDIKAAMKTASEGPLQGFLGYTEDDVVSSDFIGDNRSSIFDAKAGIQLSKTFVKVVSWYDNEFGYSQRVIDLLKHMQKVDSA
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SA190_YEAS8
Sequence: MSGSFWKFGQDYSIESPVSKILNSAFIKINKDQDDDVPTGTCEENIADDEDNSSHDYAASEDNVVNENEEKEEENTLPTTESEYENYRPNLDVLDDLLDDDELYTELMCSNFKLLIFLKYPEVLSKLIEYVTNEKILDEETDSAKKPEIIEGVNDHPILIERDRKDKKEDAEEGGDSEETTNDSDHDSGDERSVDSEETSITLPPESEEQVETRRARIAAEILSADVWPISAAIMQNKDLLGRLWSILDHPAPLPIPASTYFMKINERLLDMDITGMLEFILSRDSLVARFLTHVDNPSLMDFLLKVISTDKPDSPTGVIKILKSQELIPKLLDHLNPEYGISTQSAAGDFIKAFVTLSTNSSNELASGIGPNELTRQLVSEEMIEKLIKIMLKGGTSLSNGVGIIIELIRKNNSDYDFIQLVYTTLESHPPTDRDPIHLIHLVKLFAKHMPDFADMLDKTKLPLMEMPFGNIEPLGFERFKICELIAELLHCSNMTLLNEPNGEMIAQERDIERAKELETSTEKENITAIVDNKSSYYDKDCVEKDITENLGALQINNQGSEEDELNDTGVSSVKLDVKSDAKVVEGLENDASGVELYDETLSDTESVRECLREKPLVGDRLKIALEDTKILISILDMFTEFPWNNFLHNVIFDIAQQIFNGPLKTGYNRFLLKDYLVDAYLTKKIVDADKACQDYEKKTGLRHGYMGHLTLVAEEISKFKEYIDEMKLTFCNTAVSDRFEEPFWKEYSETILADTREKYNTVLGDFGNDQESDDDVIRNSDSEDIIGDTEGNENYGNGENDELLSNGHDSGNMDLYYNFNNNENEENEEDYAEYSDVDNKNYYNNVETNDDDYDSDDGKSKSAESEFTDKISEHRDGNSLYNEDNDENGSDKWTSGTSLFPPDHFPSRSQPSDPKLQDQNIFHHQFDFEGVGDDDDYMDPNDDGQSYARPGNPLYTTPKTPPRPKTILFNSLSALDNNGEDEEVALGTSVDDRMDNEISSDEEDSEDEDEENDMGNEEGYSLYRSRSKEAF
What is the function of this protein?
Positive regulator of protein phosphatase SIT4.  Involved in the general amino acid control (GAAC) response regulated by TOR.  Involved in the dephosphorylation of the elongator complex subunit IKI3 (By similarity).
What are the official names of this protein?
SIT4-associating protein SAP190.
What is the protein family that this protein belongs to?
Belongs to the SAPS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX32_PHOKE
Sequence: IACAPRGQLCFSDKLCCIGLRCKSRVANMWPTFCLV
What is the function of this protein?
Neurotoxin.  Causes spastic paralysis and death in mice.  Does not inhibit L-type calcium channels.
What are the official names of this protein?
U6-ctenitoxin-Pk1a, U6-CNTX-Pk1a, Neurotoxin PKTx32C4.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 53 (PNTx27C4) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPEH_BACC1
Sequence: MDTMDTMGRHVIAELWDCDFDKLNDMPYIEQLFVDAALRAGAEVREVAFHKFAPQGVSGVVIISESHLTIHSFPEHGYASIDVYTCGDRIDPNVAAEYIAEGLNAKTRESIELPRGTGSFEIKQRETKAL
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: CINAL_CITBB
Sequence: MRVAVLSIGDELLSGEVVDTNASHIADRLFQAGGRVERHLTVPDDAEAIASALTELGARSDAVIVTGGLGPTPDDLTAEAAARAAGTELELSSEALDHLERFAQRITGELHPANRRQALLPKGCRLIPNPLGTALGFVVRIGQADCFFMPGVPYEMERMLEETVLPELTGRFEAGWQRVTLKLFGIAEAAIAELLEGAIPEGSPVQLAYCVKFPEIHLILRATASDAPFLQQAAGELRQRLSAYLFAEDREEMDDRLALLLRESGLTLALAESCTGGMIAARITAVAGSSAYFLEGNVTYSNEAKTRMLQVPAPLIAEHGAVSAEVARAMAVGAREAAGSDLALSVTGIAGPDGGTPEKPVGTVYLALVDQGSCRVERFNFQGDRDRVRSITCFTALDWLRRYLLTRKTTPGRG
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: URE1_FLAJ1
Sequence: MSLKINKLKYASMYGPTKGDKIRLADTDIIVEIEKDFTVYGDENKFGGGKTIRDGMAQSSTATRDQGVLDLVITNATIIDHWGIVKADIGIKDGKIAGIGKAGNPDTMDGVEPHMIIGASTEAHGGENLIVTAGGIDTHIHFISPQQIETALYSGVTTMIGGGTGPADGTNATTITPGKWYIEKMLQAAEAFPMNLGFFGKGNCSTEAPLDEQIEAGALGLKIHEDWGASPAVIDASLKVADKYDVQVAIHTDTLNEAGFLEDTMNAINGRVIHTFHTEGAGGGHAPDIIKAAMYPNVLPASTNPTRPYTVNTIDEHLDMLMVCHHLSKNIPEDVSFADSRIRPETIAAEDILHDMGVFSIMSSDSQAMGRVGEVVTRTWQTADKMRKQRGDLAEDKGNKNDNFRAKRYVAKYTINPAIAHGISQYVGSIEVGKMADLVLWKPMLFGTKPEIIIKGGMIIAARMGDPNASIPTPQPVLYRNMFGAFGKALSKTCATFVSQASIKNNIAEEYGLEKMILPVTGCRNISKKHLIHNDKTPEITVNPENYEVRVDGEKIICEPATHLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK36_SOLLC
Sequence: MKIRASVRKICEKCRLIRRRGRIIVICSNPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: STX73_ANEVI
Sequence: MMSRLLVFLMLGAAFMLVVSANDAYGDEPAFKDLNQGDESLGKRKSCCPCWLRGNCFWGQNCYPEGCSGPKV
What is the function of this protein?
Voltage-gated sodium channel (Nav) inhibitor.  1 uM completely inhibits insect voltage-gated sodium channel inactivation (DmNav1 from D. melanogaster).
What are the official names of this protein?
Delta-actitoxin-Avd2b 3, Delta-AITX-Avd2b 3, Av7, Neurotoxin 7.
What is the protein family that this protein belongs to?
Belongs to the sea anemone short toxin (type III) family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: HEMG_ECO57
Sequence: MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQWENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTNSYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTDWEQVANFAREIAHLTDKPTLK
What is the function of this protein?
Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic condition uses ubiquinone as an electron acceptor.
What are the official names of this protein?
Protoporphyrinogen IX dehydrogenase [quinone], Protoporphyrinogen IX dehydrogenase [menaquinone], Protoporphyrinogen IX dehydrogenase [ubiquinone], Protoporphyrinogen oxidase, PPO.
What is the protein family that this protein belongs to?
Belongs to the HemG family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SYC_BEUC1
Sequence: MTLRLYDSATRAVRDFEPLEPGKVGIYLCGATVQGEPHVGHLRSVIAFDVLVRWLRRSGLDVTMIRNVTDIDDKILAKSAEAGVPWWAWAYRHERAFSDAYDAVGNLPPTYEPRATGHVVEMIELMQRLVDRGNAYRGKDGNVWFDVRSLADYGSLTRQKLENMSTLEEESSDKADPHDFALWKGLKPGDPETASWETPFGRGRPGWHLECSAMAYRYLGETFDIHGGGIDLRFPHHENEQAQSHAAGYGFARYWLHNAWVTAGGEKMSKSLGNYLTAAEALGRVPAVVLRYALASVHYRSSVEFTEATLAEARVTWERIAGFVTRAAELTGPVGDDGAARLADVVLPIAFVEAMDDDLNVSAALAVLHEHIRLGNTALSSGEAGDAAAELSAVRGMLDVLGLDPLAEPWVGEASATPLRGAVDVLVEGVLADRSAARAAKDWARADALRDQLAAAGVVVEDSPSGARWTIKGT
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y368_NITWN
Sequence: MADFLGMMKQAAQFQSKMKAMQDELDQIEVDGASGGGLVTVRMTAKMEVKGISIDPSLIKPDEREILEDLVVTALADARRKAEVAMQEKMQALTGGLGLPPGLGFS
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Nwi_0368.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LACA_STAHJ
Sequence: MTIFIGSDVAGQRLKDVVKTFLKENNHDVVDVTEGKELDFVDSTLAVVHEVQKNDDNLGIAVDAYGAGSFIVATKVKGMIAAEVSDERSAYMTRSHNNACMITMGSEIVGDTLAKNIAKEFVNGHYDGGRHQIRVDMLNKMC
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: TL14_SPIOL
Sequence: KTGVNKPELLPKEETTVIDV
What are the official names of this protein?
Thylakoid lumenal 14.7 kDa protein, P14.7.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: DCAF7_DICDI
Sequence: MEKKRIYTYNSPWVIYGLSWSSRVNRPFRLAIGSFLEDYTNRVDVIQLNEETDQFEVVCGFEHPYPPTKCMWIPDKNSNRPDLLATTGDYLRLWEVGSNQRSIKLKSLLTNVISEFCAPLSSFDWNETDPSLLATSSIDTTCTIWNIETGQAKTQLIAHDKEVFDIAFARGTDLFASVGADGSLRMFDLRNLEHSTIIYETPSFVPLLRLCWNKQDPNYLATIQQDSPKVIILDIRVPSVPAAELVFHKSAVNGISWAPHSSCHICTVSDDKQALIWDLSSMPKPIEDPLLTYNALAEINQLSWSSSQPDWIAIAFSSHLQILKV
What are the official names of this protein?
DDB1- and CUL4-associated factor 7 homolog, WD repeat-containing protein 68 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF7 family.
Protein: TODF_PSEP1
Sequence: MTNVNAEIGRMVLAGGIETNLHDVGAGNPVVLVHGSGPGVTAWANWRTVMPELSRHRRVIAPDMVGFGFTQRPHGIHYGVESWVAHLAGILDALELDRVDLVGNSFGGALSLAFAIRFPHRVRRLVLMGAVGVSFELTDGLDAVWGYEPSVPNMRKVMDYFAYDRSLVSDELAELRYKASTRPGFQEAFASMFPAPRQRWVDALASSDQDIRDIRHETLILHGRDDRVIPLETSLRLNQLIEPSQLHVFGRCGHWVQIEQNRGFIRLVNDFLAAED
What is the function of this protein?
Catalyzes the hydrolysis of 2-hydroxy-6-oxohepta-2,4-dienoate into 2-hydroxypenta-2,4-dienoate and acetate.
What are the official names of this protein?
2-hydroxy-6-oxo-2,4-heptadienoate hydrolase, HOHH.
What is the protein family that this protein belongs to?
Belongs to the DmpD/TodF/XylF esterase family.
Protein: NAGAB_CHICK
Sequence: LENGLARTPPMGWLAWERFRCNVNCREDPRQCISEMLFMEMADRIAEDGWRELGYKYINIDDCWAAKQRDAEGRLVPDPERFPRGIKALADYVHARGLKLDIYGDLGRLTCGGYPGTTLDRVEQDAQTFAEWGVDMLKLDGCYSSGKEQAQGYPQMARALNSTGRPIVYSCSWPAYQGGLPPKVNYTLLGEICNLWRNYDDIQDSWDSVLSIVDWFFTNQDVLQPFAGPGHWNDPDMLIIGNFGLSYEQSRSQMALWTIMAAPLLMSTDLRTISPSAKKILQNRLMIQINQDPLGIQGRRIIKEGSHIEVFLRPLSQAASALVFFSRRTDMPFRYTTSLAKLGFPMGAAYEVQDVYSGKIISGLKTGDNFTVIINPSGVVMWYLCPKALLIQQQAPGGPSRLPLL
What is the function of this protein?
Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides.  Required for the breakdown of glycolipids.
What are the official names of this protein?
Alpha-N-acetylgalactosaminidase, Alpha-galactosidase B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: HFQ_CUPMC
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNFRVDDSSES
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: AHPC_MYCTO
Sequence: MPLLTIGDQFPAYQLTALIGGDLSKVDAKQPGDYFTTITSDEHPGKWRVVFFWPKDFTFVCPTEIAAFSKLNDEFEDRDAQILGVSIDSEFAHFQWRAQHNDLKTLPFPMLSDIKRELSQAAGVLNADGVADRVTFIVDPNNEIQFVSATAGSVGRNVDEVLRVLDALQSDELCACNWRKGDPTLDAGELLKASA
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.  Together with AhpD, DlaT and Lpd, constitutes an NADH-dependent peroxidase active against hydrogen and alkyl peroxides as well as serving as a peroxynitrite reductase, thus protecting the bacterium against reactive nitrogen intermediates and oxidative stress generated by the host immune system.  Does not however seem to play a role in detoxification of isoniazid.
What are the official names of this protein?
Alkyl hydroperoxide reductase C, MtAhpC, Peroxiredoxin, Thioredoxin peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYV_AERPE
Sequence: MGEEFKPAIQEKRWDIGEEEKLLSLWDAEDLHKSTLDPDDPREIVVIDTPPPYPSGKWHVGGAAHYTQIDMIARYFRLKGYNVVAPFYADRNGLPVEVQVEKTYGVVAHEMARTTEGRERFLALCSEFLDKVESEIVQLWRRLGCGFDYWREGTDSPRYRSMTQATFIDLWRRGLIYEAERPVRWCPRCKTTLAEAEIEHKEDEDFIYYVKYRLEEDGRDLVVATTRPELLAGCAALAYHPEDERYKGLAGKTAIAPLYGHRVKIVEHPAVKKDFGTGLMMICSYGDEEDVRLFLELDLKPKVLIDENGVMNENAGPIAGLPVKEARRRIAEILEREGLLVKKERIVHSVPVCWRCKTPLQIIHRRELFLRQLDFKDAVKQAAAKMDFKPEMHRKKLYDWIDSIKMDWPISRERFYGTEIPLWTCEKCGAKLVPEPGRYYRPWAEEPPWDSCPRCGAPRRYLKGETRVFDTWFDSSISPLYVTRWMWDKRFYERASRNVLRPQGQDIIRTWLYYSILRVLQLTGKPAFRWVRITGLGLDPKGRPMHKSLGNVIDPEPIIAKYGGDAFRFWAAIAAKLGYDYRFDENKVKTGRNFATKLWNLARFVSSFPRPEGSPLEKATEVDKAFLALADEYLEAADKAYGELDVYEPANLIYELAWDIFASHYVELVKERSYNRSGLFTREEQEAAWATLHELLRRILVALSPIMPFVTDAIHRRLYGSSVHRQRWPDPLFTPEERRELAGKARLIVSVNKAVWNLKRSMGKKLYEPLDTVEVLVPSGIESARRDLEALHKAAIRTYTGAPPEGSEEAIPGSSVYYIAKKS
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity).
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATZ_ECOK1
Sequence: MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFAIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKAYVRAGFSKIHLDASMSCADDSIPLAPETVAERAAVLCLAAESVATDCQREQLNYVIGTEVPVPGGEASAIQSVHITQVEDAANTLRTHQKAFIARGLAEALTRVIAIVVQPGVEFDHSNIIHYQAQEAQALAQWIEKTKMVYEAHSTDYQTQTAYRELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSRCLAVIEEVMLDEPQYWKKYYRTGFNDSLLGIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQSGELSAIPHQLIMDKIYDVLRAYRYGCAE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: SURE_METNO
Sequence: MRILVTNDDGIHAPGLKVLEEIARELSDDVWVVAPETDQSGVSHSLSLNDPLRLRRVAETRFAVKGTPSDCVIMGVRHILKERGPDLVLSGVNRGQNVAEDVTYSGTVAGAMEGTILGVRSIALSQAYGVGGRANVKWHTAAEHGARTIRRILEAGIEPGILVNVNFPDCEPEAVEGIAVVAQGMRNQQLLAIDERLDGRGNPYFWLAFAKARFEPGHGTDLKAIAENRIAVTPLRLDLTDEPTLTRFAQVFG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIR2H_MYCVP
Sequence: MARTRSDSLAAGGLNWDSLPLRLFAGGNAKFWDPADIDFSRDRADWESLTDLERDWATRLCAEFIAGEEAVTQDIQPFMAAMRAEGRLGDEMYLTQFAFEEAKHTQVFRMWLDAVGITEDLQGYLDELPAYCQMFYEELPASLDALATDPSPAAQVRASVTYNHVIEGMMALTGYYAWHRICVDRGILPGMQELVRRIGDDERRHMAWGTFTCRRHVAADDANWAVFETRMNELIPLALRNTEDGFALYDEVPFGLTMEEFQQYAADKGMRRFGTISSARGRPLAEIDVDYSPLHLEDTFADEDRKSLAASA
What is the function of this protein?
Probable oxidase that might be involved in lipid metabolism.
What are the official names of this protein?
R2-like ligand binding oxidase, Ribonucleotide reductase R2 subunit homolog, Ribonucleotide reductase small subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family. R2-like ligand binding oxidase subfamily.
Protein: RL10E_HALWD
Sequence: MSDKPASMYRKLSKPSYTRRDYVTGIPGSKIAQHNMGNLQTGPQDYPVQISLRIEEECQIRHGSLESARLSANRTMLKQVGQDNYKMVLRKFPHQILRENKQATGAGADRVSDGMRQAFGKPVGTAARIQQNERVFTIYCEVDDASVAKDGLRRAYNKMSPPCRIDVEKGQKLLIS
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: HIS4_VIBC1
Sequence: MIIPALDLIEGQVVRLYQGDYGQVTEYKVDPAEQFNLYHQAGANWLHLVDLTGAKDTTARQLDLIAKLLASTPANIQIGGGVRTEQDVIDLLEAGAQRVVVGSTAVKQPELVKGWMEKYGAEKIVLALDINIYQDGTRKVAISGWQEDSGVTIEALINDYLTVGLQHVLCTDISRDGTLEGSNVELYVDLCKQYPQVQFQSSGGIGSLADIEALKGSGVAGVIVGRALLDGKFTAEEAFACWQSE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y619_METMP
Sequence: MKFRKGRPKILRLISEEPQFKLFKPVGIPRTDLESEVLTFEELESIRLVDYLNHPHEDAADEMGISRRVFWNILKSARKKVADALINGKMIDIGGGYYKIRDCNYEDECQRGKFCKYGVSNCLRLKNRDSE
What are the official names of this protein?
UPF0251 protein MMP0619.
What is the protein family that this protein belongs to?
Belongs to the UPF0251 family.