PharMolix/UniProtQA huggingface dataset:
Protein: PTHP_NEIMA
Sequence: MLKQSIEIINKLGLHARASNKFTQTASQFKSEVWVTKNDSRVNGKSIMGLMMLAAAKGTVIELETDGADEAEAMRALTDLINGYFGEGE
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I.  Phospho-HPr then transfers it to the PTS EIIA domain.
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_CAMJD
Sequence: MRANVLKRKLTLRIKRKKRIRAKISGCENFPRISVFKSNRTLYIQAIDDVKAVTLAAVDGRKLGVKANKEGAKKIAAEFAKTLKAKKIEQAVFDRNGYVYHGVIAVLAESLRENGIRL
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: ADHR_DROPE
Sequence: MYDLTGKHVCYVADCGGIALETSKVLMTKNIAKLAILQSVENPPAIAQLQSIKHSTQIFFWTFDVTMAREEMKKYFDEVMVQMDYIDVLINGATLCDERNIDATINTNLTGMMNTVATVLPYMDRKMGGSGGLIVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYTQNGVAVMAVCCGPTKVFVDRELTAFLAYGQTFADRLRRAPCQSTAVCGQNIVNAIERSENGQIWIADKGGLESVALHWYWHMADQFVNYMQSTDDEDQEFFLGQR
What are the official names of this protein?
Alcohol dehydrogenase-related 31 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MURI_LACPL
Sequence: MANEHAIGFMDSGVGGLTVVKQALKQLPRETVYFIGDQARLPYGPRPAEQVRTFSFQMADFLMAKQIKMLVIACNTATAAALPALRQQLSIPVIGVIAPGSRAALKASHRNRIGVIATEGTIRSNAYRDAILTKDPTATVVSQACPKFVPLVESNEYQSTVAKRVVAETLKQLKKQDVDTLVLGCTHYPLLRPLIQNVMGPGVTLIDSGAETVNDVSAVLDYLDIANDRSTKRYPDEYYTTGAADQFEAIARNWLGQPDFHAQHIDLGSEAND
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: Y2226_MYCTU
Sequence: MPVEAPRPARHLEVERKFDVIESTVSPSFEGIAAVVRVEQSPTQQLDAVYFDTPSHDLARNQITLRRRTGGADAGWHLKLPAGPDKRTEMRAPLSASGDAVPAELLDVVLAIVRDQPVQPVARISTHRESQILYGAGGDALAEFCNDDVTAWSAGAFHAAGAADNGPAEQQWREWELELVTTDGTADTKLLDRLANRLLDAGAAPAGHGSKLARVLGATSPGELPNGPQPPADPVHRAVSEQVEQLLLWDRAVRADAYDAVHQMRVTTRKIRSLLTDSQESFGLKESAWVIDELRELADVLGVARDAEVLGDRYQRELDALAPELVRGRVRERLVDGARRRYQTGLRRSLIALRSQRYFRLLDALDALVSERAHATSGEESAPVTIDAAYRRVRKAAKAAKTAGDQAGDHHRDEALHLIRKRAKRLRYTAAATGADNVSQEAKVIQTLLGDHQDSVVSREHLIQQAIAANTAGEDTFTYGLLYQQEADLAERCREQLEAALRKLDKAVRKARD
What are the official names of this protein?
Uncharacterized protein Rv2226.
Protein: RK123_ARATH
Sequence: MASTTLSIATTIRSSSPLTSASTHHFLSKPTAIEFPFRLSSSSSHRAINLRPISAVEAPEKIEKIGSEISSLTLEEARILVDYLQDKFGVSPLSLAPAAAAVAAPADGGAAAVVEEQTEFDVVINEVPSSSRIAVIKAVRALTSLALKEAKELIEGLPKKFKEGITKDEAEEAKKTLEEAGAKVSIA
What are the official names of this protein?
50S ribosomal protein L12-3, chloroplastic, CL12-C.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CUO7_BLACR
Sequence: DHIVSPHGFSYTSASLSPYVYAPYTYAASPYINPASVAVAPVNVATSYHAQDVIGQASYGHVDAYQAHHAVQDAAGNKVGSYSYVSPEGKVVKTNYVADATGFHVASNALPVGPTVVPAPVVDTPEVAAAKAAHLLEVEKVKGRV
What are the official names of this protein?
Cuticle protein 7, BcNCP15.0.
Protein: CKLF4_MOUSE
Sequence: MRGGEELDGFEGEASSTSMISGASSPYQPTTEPVSQRRGLAGLRCDPDYLRGALGRLKVAQVILALIAFICIETIMECSPCEGLYFFEFVSCSAFVVTGVLLILFSLNLHMRIPQINWNLTDLVNTGLSTFFFFIASIVLAALNHKTGAEIAAVIFGFLATAAYAVSTFLAMQKWRVSVRQQSTNDYIRARTESRDVDSRPEIQRLDT
What is the function of this protein?
Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity.  May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.
What are the official names of this protein?
CKLF-like MARVEL transmembrane domain-containing protein 4, Chemokine-like factor superfamily member 4.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: FECB_ECOLI
Sequence: MLAFIRFLFAGLLLVISHAFAATVQDEHGTFTLEKTPQRIVVLELSFADALAAVDVIPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDLIIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQHKERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPSIGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRGIFAAERIAADTVKIFHHQPLTVVK
What is the function of this protein?
Binds citrate-dependent Fe(3+); part of the binding-protein-dependent transport system for uptake of citrate-dependent Fe(3+).
What are the official names of this protein?
Fe(3+) dicitrate-binding periplasmic protein, Iron(III) dicitrate-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 8 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSTB_SHEDO
Sequence: MISIDQRAMQAKPIDLEHLSAQDTALEIRNLDLSYGDKQALFNVSMKIPKKQVTAFIGPSGCGKSTLLRCINRMNDLVDSCKIKGEILLHGQNIYDKKVDVAALRRNVGMVFQRPNPFPKSIYENVVYGLRLQGLNNRRDLDEAAERSLRGAAIWDEVKDRLHDNAFGLSGGQQQRLVIARAIAIEPEVLLLDEPTSALDPISTLTIEELITELKDKYTVVIVTHNMQQAARVSDQTAFMYMGELVEYADTNTIFTTPRKRKTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HLDD_NEIMA
Sequence: MTIIVTGAAGFIGSNIVKALNQRGITDIVAVDNLSKGEKFKNLAECEIAHYLDKHEFIRQVREHILPYQNIEAVFHQGACSDTMNYDGLYMMDNNYQYTLDLLDWCQDERIPFLYASSAAVYGKGEIFREERELEKPLNVYGYSKFLFDQVLRRRMKEGLTAQVVGFRYFNVYGQHEQHKGRMASVAFHHFHQYREHGYVNLFGSNDGYGNGEQTRDFVSVEDVAKVNLYFFDHPELSGIYNLGTGRSQQFNELAAATVNACRAAEGKPEMSLKELVEEELIRYIPFPNALKGKYQSFTQADITKLREAGYKEEFFDVKAGIDRYVKWMLENLA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: ATPF_TROW8
Sequence: MKFAQPHNPLLPSVPDIVFSAIVLAIVLPFFWWFVIPRISKLLSDRSSLIEGKISEAASAHARALETLELRKQQLDEAKSEASQIRQEARDDAQLILQQARETADETAERVMLHAREQIQAEKAAALLSLRSEIATLALAAAGKAVSEKLDDDKKSRELVSASIAKMAEDAG
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RSMG_ECO8A
Sequence: MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVRDPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRVRFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGRFYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_BRASB
Sequence: MAQPSFFQSPPPTTLAAIAAAANATLVDASRGEQVITGLAALDEAGPMHLAFFDNLKYADQLAMTKAGACLVSPRFEARVPSHVAVVRANQPFRAFVQLARTMHADALRPQSWFGCDGISSQAIIDPSARLEDGVVVEPLAVIGAHVEIGAGTIVGAGAVIGPHVKIGRDCNVGARTVIQCALIGNDVLIHPACAIGQDGYGFIFFGPGGHVKVPQTGRVIIQNHVEIGAGTTIDRGSLRDTVIGEGTKIDNQVQIGHNVTIGRHCLLAAQIGLAGSLTIGDNVALGAKVGINNHLTIGDGAQVTAMSGVKDDIPPNGRWGGFFAKPTKQWFREIVAVERLVRDQTATNKDEGQE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: BIOD_BUCAI
Sequence: MIKKFFITGTDTNVGKTIVSSILLKKATMSGYQTAGYKPVSSGGQKKSSGFFNQDAILLKKSSSIILSDREVNPIAFFENAPPHILSKFQKRSIKKEELSLGLNNITKKSNWILVEGAGGWYTPLSCKDTFSSWVKQEKLTVIIIIAIKLGCINHAILTEKAIISDQIKCGGWIANNIFPKDKYNMHYIQTLLNYIKSPFLGVVPYFKNKNRINFKKIKIKLPK
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LLDD_PSEPW
Sequence: MIISASTDYRAAAQRKLPPFLFHYADGGAYAEHTLRHNVSDLAGIALRQRVLKNMSELSLETRLFDETLSMPVALAPVGLTGMYARRGEVQAARAAAAHGIPFTMSTVSVCPIEEVAPAIDRPMWFQLYVLKDRGFMRNALERAKAAGVKTLVFTVDMPVPGARYRDAHSGMSGANGPMRRVLQAMTHPEWAWDVGVMGRPHDLGNISKYRGNPTGLADYIGWLGSNFDPSISWKDLEWIREFWDGPMIIKGILDADDARDAVKFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDLKILADSGIRSGLDVVRMIALGADTVLIGRAFLWALAVHGQAGVKNLLELFEKEMRVAMVLTGAKAISEISRDSLVRELGA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RSMJ_SALPK
Sequence: MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPLADVATPNAIVTKGHRFDIYAGTPLTE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_HAEDU
Sequence: MSYFAEKLAELAQVGLNRSLPEIEHQGKWIIAQNRKMLNFSSNDYLGLASDTELQQTFLQNILQEAPLHQWFSSSSSRLLTGNFPIYARLEQLLAQRFQRETALLFNSGYHANIGILPALVDKHSLILADKLVHASLIDGTRLAGCDFYRYQHNNLAHLTQLLEKHTGQYRRIIIVTESVFSMDGDVAPLPQLVALKKAFSSQTEVMLYVDEAHAIGVYGANGLGMAEFFDCIDDIDLLVGTFGKALASMGAYLICDQLIKQYLVNTMRPLIFSTALAPINVAWTHFLFEKLPQFQPKRAHLARLSQQLKQAVELRNGDTLATQSCIVPFVVGENRQAVEKSQYLQQQGYYCLPIRPPTVPKGTARIRFSLTADLTEAELNGLIACL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: DRE2_PARBA
Sequence: MLPSQTPAQGSGRFLLLSPPSLSSHPEKLNAILGLHARESTDLQMLDRLALGLVSLPQSTYDVVLLLTGADNTLAETYRLVSRGVLQGVVNSLKPGGKLRNRDNQIWGSGSDSAAGLGSSDGGGGGGGGEKKSSSEQAFRNEAILAGLVFDDRGELAKPDFGAQQAVPLKLGRKKNLGDSAFGNGTVELPASNGVRVTAGATTTTPTTTTTTTINSSTPSGVRFIDFSDDFGVPMVEETQELDEELIDEEELLGEFDMGRPIVQPPECRPKAGKRRRACKDCTCGLSQKLEAEDRAKRANADKALETLKLGTNDLAEVDFTVQGKVGSCGNCALGDAFRCDGCPYIGLPAFKPGEEVRLLNNDVQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35.  Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18.  TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
What are the official names of this protein?
Fe-S cluster assembly protein DRE2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.
Protein: RL18_PROMM
Sequence: MSNLSRKQQTQKRHRRLRRHLKGTAQRPRLAVFRSNNHIYAQVIDDEAQNTLCAASTLDKDLRTSLKADGSSCDASNAVGDLVAKRALAKGIQQVVFDRGGNLYHGRVKSLADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: PYRB_STRS7
Sequence: MSVVNNRVALKHLVSMEHLTNEEVMGLISRGSEYKAGKVAIKDNSRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALGTEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGLKIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLDVLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADHLVEAPKARIVAQMANGVFVRMAIIEAILNGRNENV
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: MTNW_BACC7
Sequence: MSGIIATYLIHDDSHNLEKKAEQIALGLTIGSWTHLPHLLQEQLKQHKGNVIHVEELAEHEHTNSYLRKKVKRGIIKIEYPLLNFSPDLPAILTTTFGKLSLDGEVKLIDLTFSDELKKHFPGPKFGIDGIRNLLQVHDRPLLMSIFKGMIGRNIGYLKTQLRDQAIGGVDIVKDDEILFENALTPLTKRIVSGKEVLQSVYETYGHKTLYAVNLTGRTFDLKENAKRAVQAGADILLFNVFSYGLDVLQSLAEDDEIPVPIMAHPAVSGAYSASKLYGVSSPLLLGKLLRYAGADFSLFPSPYGSVALEKEEALAISKYLTEDDAFFKKSFSVPSAGIHPGFVPFIVRDFGKDVVINAGGGIHGHPNGAQGGGKAFRAAIDATLQNKPLHEVDDINLHSALQIWGNPSHEVKL
What is the function of this protein?
Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P).
What are the official names of this protein?
2,3-diketo-5-methylthiopentyl-1-phosphate enolase, DK-MTP-1-P enolase, RuBisCO-like protein, RLP.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type IV subfamily.
Protein: SNX33_XENTR
Sequence: MALKARALYSFQGENKEEINILENEELHLFSDVSLDGWLQGTNSRGQTGLFPASYVEILRPRSGSVQVDYSGHTQGYTDSPHQGSYDDDEEDDDDWDDWDDGQTVVDEPSGSNGVSRSQLQHHHHYPRPEYTHRPRPALERQDSIASGKRGSVVGRNLNRFSSFVRSGVEAFVLGDVPQFGGVSESHAIEMGPKGPQWKANPRPFSCSVEEPTKQTKFKGIKSYISYRLTPDPCNSPVYRRYKHFDWLYNRLLHKFTVISVPHLPEKQATGRFEEDFIQKRKRRLVLWMDHMTSHPVLSQYDGFQHFLSCQDEKQWKAGKRRAERDELVGASFLLTLQLPTEHQDLQDVEERVDVFKAFSKKMDENVLQLSSVVSELARKHLGGFRKEFQRLGAALQGLSHSFQLDPPYSSEPLVGAISHTGRTYEAVGEMFAEQPKNDQFRFLDTLSLYQGLLSNFPDIIHLQKGAFAKVKESQRMSDEGRMEQDEADGIRKRCRVVGFALQAEINHFHQRRLQDFKQAIQHYLKEQILFYRRVSQELEKTLHMYDDL
What is the function of this protein?
Plays a role in the reorganization of the cytoskeleton, endocytosis and cellular vesicle trafficking, both during interphase and at the end of mitotic cell divisions.  Required for efficient progress through mitosis and cytokinesis.  Required for normal formation of the cleavage furrow at the end of mitosis.  Modulates endocytosis of cell-surface proteins.  Promotes membrane tubulation (in vitro).  May promote the formation of macropinosomes (By similarity).
What are the official names of this protein?
Sorting nexin-33, SH3 and PX domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily detected in the cytosol. A minor proportion is membrane-bound (By similarity).
Protein: ATPF_FRASN
Sequence: MLQNLVLAAAEEGAEHEDSVLVPPLAELIVGLLAFGLLVGFFFWKIYPQIRKTYAERAERIEGGLNRAERAEREAQALLEQYRSQLAEARSEAARIREDAQAQGRQIVEELRTQVQQEVAEIRERADAALVAERAQVVASVRREIGEIALELATRIVGRELENDTRQRQLVDDFIAGLDEAPQPDAVPAGPGV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: COX3_PAPHA
Sequence: MTHQLHAYHMVKPSPWPLTGALSAFLLTSGLIMWFHFYSTALLTLGLLTNVLTMYQWWRDIIRESTYQGHHTTPVQKSLRYGMTLFIISEVFFFAGFFWAFYHSSLAPTPRLGCHWPPTGITPLNPLEVPLLNTSVLLASGVTITWAHHSLMNGNRKQTIQALLITILLGTYFTLVQISEYFEAPFTISDGIYGSTFFVATGFHGLHVIIGSTFLLICLIRQLFYHFTPSHHFGFEAAAWYWHFVDVIWLFLYISIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MALT_ECOL6
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVMYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFESAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: FADJ_VIBC1
Sequence: MSEQKAFSLKIDEQNIAWLAIDVPNEKMNTLQAAFADEMKEIFAQLKDTSGVKGMVIHSLKPDNFVAGADVRMLEACTTASEAEALAKQGQELFQQLSDLPYPVVAAIHGPCLGGGLELALACDYRVCTDSDKTRLGLPEVQLGLLPGSGGTQRLPRLIGLLPSLDLILTGKQLRAKKAKKLGVVDACVPETVLLDIAKMHVEKGKKKGKQKQSTKEKLMSGSGLGRKFVFEQAAKKTNEKTRGNYPATVAILEVIQHGLEKGFAQGQELEAKRFGELVMSSESKALRSIFFATTEMKKENGAEAEPTAVNKVGVLGGGLMGAGISHVSVAKAKVPVRIKDVSNDGVLNALNYNYKLFEKQRKRRIISKAGLQSKMLQLSGGIDFTSFNHIDVVIEAVFEDLDLKQAMVADIEANAKPETIFATNTSSLPIHKIAEKAERPENIVGLHYFSPVEKMPLVEVIPHETTSEETISTVVALAKKQGKTPIVVKDKAGFYVNRILAPYMNEAAHILLANEPIEQLDGALLDFGFPVGPITLLDEVGVDIGAKIMPILVNELGERFKGPDVFDTLLNDGRKGRKTGKGFYTYKGKKKEVDKSVYKLLNLTPESKLSDNDIALRCVLPMLNEAVRCLDDGIIRSPRDGDIGAIFGIGFPPFLGGPFCYMDQFGLKELVEKMNEFASKYGDRYAPCDGLLTRAGEGRNFYD
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CORO6_HUMAN
Sequence: MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAEQARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD
What are the official names of this protein?
Coronin-6, Coronin-like protein E, Clipin-E.