PharMolix/UniProtQA huggingface dataset:
Protein: GSA_SYMTH
Sequence: MTARYERSAALYERAVARIVGGVNSPARSFKSVGGGAPVFMARGQGPYLYDVDGNRYIDYIGAFGAGMFGHGHPELVAAVARAAEGGTIYGTPNPWEVELAERIHQALPSMERIRFVTTGTEAVMSAVRVARAFTGRPKIIKMEGCYHGHSDFALIAAGSGPSQLGTPDSAGVTEGVAQDVITVPYNDLDSLGEALDVWGPQVAAVLVEPIVGNFGVAMPKPGYLEGVKRLAHAHGALLIFDEVITGFRVAYGGAQTLLGIEPDLTTLGKIIGGGLPLAAYGGRAEIMDWVAPLGPAYQAGTLAGNPLCMQVALTGLEILSRPGVYERLDADAAYLADGLVRSARSHGHTVQLGRAGSMFTLFFCDEPVVDYRTAQRSDPAKFAAMFRGLLDRGIALAPSRFEAWMLTVQHTRADLEETLQIADEVFAQMAGQ
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNA1_AERPE
Sequence: MFRYEAKVFKELVDSVSKILDEGLFIITGEGLRLRGMDPARVALVDIEIPSSSFFDFYMAGDVERVELGVNMETLKGVVARAKKGDQLEVRVREDKVLFIVESVVLRRYLLPNLEVIVDVPEDISLEFDATATVIADVVKKTLRDVELVGDIVEFDAGEDYLSIRSVGPERRRVETRLTRESPALIDLEVKEPATSRYDVGYLKRMLGVAKIAESIELSFSTDKPLKMVFKSPDGSRVTYLLAPSTG
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp 1, Proliferating cell nuclear antigen homolog 1, PCNA 1.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: RL32_BACP2
Sequence: MAVPFRRTSKMKKRLRRTHFKLQVPGMVACPECGEMKISHRVCKSCGTYKGKDVKSN
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: THI4_SCLS1
Sequence: MAPPSAVEANSPIDGVHLKSAFEVKAVHAQTASQGKTLAELAEKWDQGFTFAPIRESQVSRAMTRRYFKDLDTYAESDVVIVGAGSCGLSTAYMLGKARPDLKIAIIEASVSPGGGAWLGGQLFSAMVMRKPADAFLIDLGVPFEDEGDFVVVKHAALFTSTLLSKVLAFPNIKLFNATSVEDLITRQTADGNIRIAGVVTNWTLVTMHHDDQSCMDPNTINAPIVISTTGHDGPFGAFCVKRLVSMNQIKELGGMRGLDMNVAEDAIVKKTREIVPGLIVGGMELSEVDGANRMGPTFGAMALSGVKAAEEALKVFDERKAQNAY
What is the function of this protein?
Involved in biosynthesis of the thiamine precursor thiazole.  Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate.  The reaction includes an iron-dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.  May have additional roles in adaptation to various stress conditions and in DNA damage tolerance.
What are the official names of this protein?
Thiamine thiazole synthase, Thiazole biosynthetic enzyme.
What is the protein family that this protein belongs to?
Belongs to the THI4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MTLD_LACLA
Sequence: MKKAVHFGAGNIGRGFIGEILSKNGFDIHFVDTNKSIIAELNNRHSYEIGIASSEHEKISVKAVSGINNSENPEAVIEAIAKADILTTAIGPNVLPYIAELIAKGLQKRKEEKVQSPLDIIACENMIGGSEFLEEKVSDYLSESDKLYLSKFIGFPNAAVDRIVPAQKHKDVLYVEVEPFSEWVIDASHLKNKEIKLEGVHYTTDLEPFIERKLFSVNSGHAAVAYSSAYKGYKTILEGLQDEEILNILKAVQKETRALLLAKWAQYFKQDELIKYHELIISRFSNPEIIDEVSRVARTPIRKLGYDERFIRPIRELNDRKLSYQNHLDIVGKIFAYHDENDAQAIQLQEKLKITELPMLIEEVTGLSNQKLILEIEKVINHYKK
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RBL1P_CUPNH
Sequence: MNAPESVQAKPRKRYDAGVMKYKEMGYWDGDYEPKDTDLLALFRITPQDGVDPVEAAAAVAGESSTATWTVVWTDRLTACDMYRAKAYRVDPVPNNPEQFFCYVAYDLSLFEEGSIANLTASIIGNVFSFKPIKAARLEDMRFPVAYVKTFAGPSTGIIVERERLDKFGRPLLGATTKPKLGLSGRNYGRVVYEGLKGGLDFMKDDENINSQPFMHWRDRFLFVMDAVNKASAATGEVKGSYLNVTAGTMEEMYRRAEFAKSLGSVVIMIDLIVGWTCIQSMSNWCRQNDMILHLHRAGHGTYTRQKNHGVSFRVIAKWLRLAGVDHMHTGTAVGKLEGDPLTVQGYYNVCRDAYTHTDLTRGLFFDQDWASLRKVMPVASGGIHAGQMHQLIHLFGDDVVLQFGGGTIGHPQGIQAGATANRVALEAMVLARNEGRDILNEGPEILRDAARWCGPLRAALDTWGDISFNYTPTDTSDFAPTASVA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, plasmid, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
Protein: RXL7_GEOSW
Sequence: MSYEKVLQAGKTVVGTKQTVRALKEGKALEVIVAEDADPSIIDKVMEAAKEANVPVTKVDSMKKLGKACKIQVGAAAVAIIR
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: GYRB_STAAU
Sequence: MVTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGLHHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTDNGRGIPVDIQEKMGRPAVEVILTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQFDLKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERDEENVREDSYHYEGGIKSYVELLNENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATNLLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEEKDRLSGEDTREGMTAIISIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARARVAAKKAREVTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSRTQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTDADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRELDKLKSELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGDVVENRRQFIEDNAVYANLDF
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_HUMAN
Sequence: MAGAATQASLESAPRIMRLVAECSRSRARAGELWLPHGTVATPVFMPVGTQATMKGITTEQLDALGCRICLGNTYHLGLRPGPELIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFRSPYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIRWLDRCIAAHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFWRMVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVPTGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAVRTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDALASVGITLG
What is the function of this protein?
Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (PubMed:11255023, PubMed:20354154).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product (By similarity).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase catalytic subunit 1, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Note=Weakly associates with mitochondria, possibly via QTRT2.
Protein: RPE_SYNY3
Sequence: MSKNIVVAPSILSADFSRLGEEIKAVDEAGADWIHVDVMDGRFVPNITIGPLIVDAIRPLTKKTLDVHLMIVEPEKYVEDFAKAGADIISVHVEHNASPHLHRTLCQIRELGKKAGAVLNPSTPLDFLEYVLPVCDLILIMSVNPGFGGQSFIPEVLPKIRALRQMCDERGLDPWIEVDGGLKPNNTWQVLEAGANAIVAGSAVFNAPNYAEAIAGVRNSKRPEPQLATV
What is the function of this protein?
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
What are the official names of this protein?
Ribulose-phosphate 3-epimerase.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
Protein: GFA_BRASO
Sequence: MTVHIHPSVDHGVKQGSGHFAGGTLVCKCHDRPVKVGIKGDVAHNHACGCTKCWKPSGATFSVVAVVPRQNVTVLENGDKLKIVDASAVIQRYACTGCGTHMYGRIENTGHPFYGLDFIHPELFQEQGSAAPGFAAFVSSVIESGVKPEQMGEIRARLKELGLEPYDCLSPALMDAIATHVAKAKAA
What is the function of this protein?
Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione.
What are the official names of this protein?
Glutathione-dependent formaldehyde-activating enzyme, S-(hydroxymethyl)glutathione synthase.
What is the protein family that this protein belongs to?
Belongs to the Gfa family.
Protein: LEPA_ANADE
Sequence: MAEKNSHIRNFSIIAHIDHGKSTLADRLLEHTGTVTKREAQAQFLDNMELERERGITIKAQTVRMKYRAQDGRDYELNLIDTPGHVDFAYEVSRSMAACEGAILVVDATQGVEAQTLANVYQALDHDLEIVPVINKIDLPSADVEGVRQEIEEVIGLDAKDAVPASAKEGIGIGEILEQIVHRVPPPEGDPEAPLKAIVFDSWYDSYRGVVMLVRVFEGTVRPKQKIRLWSNRKEFEVQELGIFAPFAKAVGELQAGEVGVVVANVKDVHDAKVGDTITDAARPTEAPFPGFKVVKPMVFSGVFPIEAADYEQLRDALEKLSLNDSAFTYEPETSQALGFGFRCGYLGLLHMEIVQERLEREYQLALITTAPSVVYRVTDTTGAVEEIDNPAKLPPVQKIAKLEEPHLTCHIHARTEDVGAILKLCQERRGLQRDLKYLGTKRVQITYDIPLAEVVFDFFDKLKSVSRGYASLDYELKGYEEADLVKLDILINGEPVDALSVIVHRERAYQRGRDLCQRLREVIPKQMYEVAIQAAIGAKVIARETVKAFRKNVLAKCYGGDISRKRKLLEKQKEGKKRMKQVGSVEIPQEAFLAVLKVEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MNTP_PARPJ
Sequence: MNPVATLFLAFAMSTDAFAAAIGKGATLNRPHWREAVRTGLIFGVIEALTPLVGWFLGKAAAQYVSAWDHWIAFSLLLVLGARMVFNSFNTKEVEETKPSAHSFWLLALTGFATSIDAMAVGAGLAFVDVNIYSTAAAIGLATMAMVTIGVMLGRVIGHVAGRRAELAGGIVLIGIGSTILAEHLNIFG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDPAS_THEGJ
Sequence: MGALSSMFWALWYILPAYFANASPVLLGGGRPIDGGRKWRDGNRILGDGKTWRGFLGGVSVGTLVGVLQYYLTPAFYGSLKTAVLLAFLLSFGALMGDLVGSFIKRRLNLPRGYPAVGLDQLGFLISALAFAYPVKTISSGQMLFLLIFTPLVHWGANYFAYKMGWKSVPW
What is the function of this protein?
Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP.  This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
What are the official names of this protein?
CDP-archaeol synthase, CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-archaeol synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1059_CLOTE
Sequence: MNLYDKAHELARVLKDCPEVVELRNTSVKMKENEDNLKMLKDFRQLQYEAYYEQLNNEKISEETETKLNKLGSIIAMNKTVSNYLEAESRFAVIWEDLIKILNEAVDVDLSFESKK
What are the official names of this protein?
UPF0342 protein CTC_01059.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: ATPG_CERS4
Sequence: MPSLKDLKNRIGSVKNTRKITKAMQMVAAAKLRRAQEAAEAARPFAERMTAVMTGLAGSVGSSESAPRLLAGTGSDKVHLLVVMTAERGLCGGFNSSIVRLARAHAAKLLTQGKTVKILTVGKKGREQLRRDLGQHFIGHVDLSEVKRMGYPVAQGIARDLLDRFDKGEFDVATIFFARFQSVINQVPTAQQVIPAVFEGEGEVSSLYDYEPSEEGVLADLLPRGVATQIFTALLENGASEQGARMSAMDNATRNAGDMINRLTIEYNRSRQAAITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUOC_BURA4
Sequence: MASKIEILKANLEAALGARVVSLTEAIGELTLVVKASDYLEVAKTLRDDPKLRFEQLIDLCGVDYQTYGDGAYDGPRFAAVSQLLSVTNNWRLRLRVFAPDDDLPIVASLVDIWTSANWYEREAFDLYGLVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PURA_DESDA
Sequence: MANTVIIGAQWGDEGKGKIVDMLSAQSRAIVRFQGGNNAGHTIKVQGEETILHLIPSGILHADKMCLIGNGVVLDPHVFLEEVDHLAAKGVDVSAARLGISKKAHLIMPYHKSLDKAREAKRASHKIGTTGRGIGPCYEDKAARVGLRAGDLANPDLVRAKVAHALQEKNTLLRDLYKFDPLDEAAVCQELLALAPRLLPYLTEVEDHIQKIQAQGGDILFEGAQGIHLDIDHGTYPFVTSSNTVSGNASAGCGVGPSALHRVVGIVKAYTTRVGSGPFPTEQLDDTGSYLRTQGHEFGATTGRPRRCGWLDAVVLRESVRLCGMTDIALTKLDVLQNLPGLRICVAYEYEGHKLDYMPQEEGALEKVTPVYEDLPGFEEDITGCTRFDDLPETVRAYIARIEELVGVKVSMVSVGAERRQTIVR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COL6_CAEEL
Sequence: MDVKETEEQRQMRRIAFVAVVVSTAAVIASVVTLPMLYNYVQSFQSHLMVETDYCKARSRDMWLEMTALQAGKGMGHRMKRAWLFGQWIPETSAGGGGSGNGGGNYGSGASTGGGANTAGYGGYGAAVNAEPAAVCCTCNQGAAGPPGPEGPPGNDGKDGRNGNDGKNGRDAEVLPAPASEPCIICPTGAPGPMGAMGPKGPPGPKGSPGEPPQDGKSGDDGMAGQPGPIGRPGRDGMKGAPGAAGRLIPVPGPQGAPGKPGPIGPPGPKGNPGPDGQSYQGPPGPPGDSGTPGHEGRAGPNGPAGPPGDNGEKGDCGHCPPPRTPPGY
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins.  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment.
What are the official names of this protein?
Cuticle collagen 6, Protein roller-8.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: XCL1_HUMAN
Sequence: MRLLILALLGICSLTAYIVEGVGSEVSDKRTCVSLTTQRLPVSRIKTYTITEGSLRAVIFITKRGLKVCADPQATWVRDVVRSMDRKSNTRNNMIQTKPTGTQQSTNTAVTLTG
What is the function of this protein?
Chemotactic activity for lymphocytes but not for monocytes or neutrophils.  In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
What are the official names of this protein?
Lymphotactin, ATAC, C motif chemokine 1, Cytokine SCM-1, Lymphotaxin, SCM-1-alpha, Small-inducible cytokine C1, XC chemokine ligand 1.
What is the protein family that this protein belongs to?
Belongs to the intercrine gamma family.
What are the subcellular locations of this protein?
Secreted.
Protein: QSED_ECO57
Sequence: MTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRKIKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLLEAPFDHIRLFESQLFPVCASDEHGEALFDLVQPHFPLLNYSRNSYMGRLINRTLTRHSELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGQLVVLNRDELVIPIQAYAYRMNTRMNPVAERFWRELRELEIVLS
What is the function of this protein?
Represses EHEC virulence expression.  Down-regulates expression of LEE (locus of enterocyte effacement) and iraD genes, and alters AE (attaching and effacing) lesion formation.  May regulate transcription through interactions with another HTH DNA-binding protein.
What are the official names of this protein?
HTH domain-truncated transcriptional regulator QseD, Quorum-sensing regulator protein D.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: NRDR_ANOFW
Sequence: MKCPSCHHNGTRVLDSRPADEGRSIRRRRECERCHFRFTTFERVEETPLIVVKKEGTREEFSREKILRGLIKACEKRPVALEQLEEVTQQIERELRNSGINEVKSETIGEMVMEQLSKIDEVAYVRFASVYRQFKDLNVFIEELKELIKKEQGERA
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: LPXA_BURVG
Sequence: MTRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKNEPTRLVIGNRNTIREFTTIHTGTVQDAGVTTLGDDNWIMAYVHIGHDCRVGNNVILSSNAQMAGHVEIGDFAIIGGMSGVHQFVRIGAHSMLGGASALVQDVPPFVIAAGNKAEPHGINVEGLRRRGFSPDAISALRSAYRLLYKNGLSLDEAKVQLRELASAGGDGDAPVAALVAFVDASQRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIPS2_SORAU
Sequence: MAPSVKDQVEPQHAKILAIGTANPPNVYYQEDYPDFLFRVTKNEHRTDLREKFDRICEKSRTRKRYLYLTEEILKANPCIYTYGAPSLDVRQDMLNPEVPKLGQEAALKAIKEWGQPISKITHLIFCTASCVDMPGADFQLVKLLGLNPSVTRTMIYEAGCYAGATVLRLAKDFAENNEGARVLVVCAEITTVFFHGLTDTHLDILVGQALFADGASAVIVGANPEPEIESPLFEIVACRQTIIPNSEHGVVANIREMGFNYYLSGEVPKFVGGNVVDFLTKTFEKVDGKNKDWNSLFFSVHPGGPAIVDQVEEQLGLKEGKLRATRHVLSEYGNMGAPSVHFILDEMRKKSIEEGKATTGEGLEWGVVIGIGPGLTVETAVLRSEFITC
What is the function of this protein?
Type III polyketide synthase involved preferentially in the biosynthesis of 4-hydroxycoumarin from salicoyl-CoA.  Can also use benzoyl-CoA and malonyl-CoA to produce 3,5-dihydroxybiphenyl as a major product and benzoyldiacetic acid lactone as a minor side product.  Can also use m-hydroxybenzoyl-CoA as substrate, producing m-hydroxybenzoyl diacetic acid lactone as a derailment product.  No activity with p-hydroxybenzoyl-CoA, CoA-linked cinnamic acids or acetyl-CoA.
What are the official names of this protein?
4-hydroxycoumarin synthase 1, Biphenyl synthase 2, SaBIS2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: UB2G2_MOUSE
Sequence: MAGTALKRLMAEYKQLTLNPPEGIVAGPMNEENFFEWEALIMGPEDTCFEFGVFPAILSFPLDYPLSPPKMRFTCEMFHPNIYPDGRVCISILHAPGDDPMGYESSAERWSPVQSVEKILLSVVSMLAEPNDESGANVDASKMWRDDREQFYKIAKQIVQKSLGL
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-48'-linked polyubiquitination.  Involved in endoplasmic reticulum-associated degradation (ERAD).  Required for sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 G2, E2 ubiquitin-conjugating enzyme G2, Ubiquitin carrier protein G2, Ubiquitin-protein ligase G2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lipid droplet.
Protein: RS20_LACAC
Sequence: MPQIKSAIKRVKTQNATNKRNASELSKLRTAIKKFKNAVETDSKEDVSKLHLEAVRALDKAASKGLIHKNKAARDKSRLTKLANK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SYA_MYCTA
Sequence: MQTHEIRKRFLDHFVKAGHTEVPSASVILDDPNLLFVNAGMVQFVPFFLGQRTPPYPTATSIQKCIRTPDIDEVGITTRHNTFFQMAGNFSFGDYFKRGAIELAWALLTNSLAAGGYGLDPERIWTTVYFDDDEAVRLWQEVAGLPAERIQRRGMADNYWSMGIPGPCGPSSEIYYDRGPEFGPAGGPIVSEDRYLEVWNLVFMQNERGEGTTKEDYQILGPLPRKNIDTGMGVERIALVLQDVHNVYETDLLRPVIDTVARVAARAYDVGNHEDDVRYRIIADHSRTAAILIGDGVSPGNDGRGYVLRRLLRRVIRSAKLLGIDAAIVGDLMATVRNAMGPSYPELVADFERISRIAVAEETAFNRTLASGSRLFEEVASSTKKSGATVLSGSDAFTLHDTYGFPIELTLEMAAETGLQVDEIGFRELMAEQRRRAKADAAARKHAHADLSAYRELVDAGATEFTGFDELRSQARILGIFVDGKRVPVVAHGVAGGAGEGQRVELVLDRTPLYAESGGQIADEGTISGTGSSEAARAAVTDVQKIAKTLWVHRVNVESGEFVEGDTVIAAVDPGWRRGATQGHSGTHMVHAALRQVLGPNAVQAGSLNRPGYLRFDFNWQGPLTDDQRTQVEEVTNEAVQADFEVRTFTEQLDKAKAMGAIALFGESYPDEVRVVEMGGPFSLELCGGTHVSNTAQIGPVTILGESSIGSGVRRVEAYVGLDSFRHLAKERALMAGLASSLKVPSEEVPARVANLVERLRAAEKELERVRMASARAAATNAAAGAQRIGNVRLVAQRMSGGMTAADLRSLIGDIRGKLGSEPAVVALIAEGESQTVPYAVAANPAAQDLGIRANDLVKQLAVAVEGRGGGKADLAQGSGKNPTGIDAALDAVRSEIAVIARVG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBJ_CHLSC
Sequence: MADTTGRIPLWLIGTVTGIPVIGSIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.