PharMolix/UniProtQA huggingface dataset:
Protein: ANXA1_RABIT
Sequence: MAMVSEFLKQAWFIDNEEQDYINTVKTYKGGPGSAVSPYPAFNPSSDVAALHQAIMVKGVDEATIIDILTKRNNAQRQQIKAAYLQEKGKPLDEVLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASRNNKEIREINRVYREELKRDLAKDIASDTSGDFQKALLSLAKGDRSEDFGVNEDLADTDARALYEAGERRKGADVNVFTTILTTRSYLHLRRVFQKYSKYSQHDMNKVLDLELKGDIEKCLTAIVQCATCKPAYFAEKLYQAMKGAGTRHKALIRIMVSRSEVDMNDIKAFYQKKYGVSLCQAILDETKGDYEKILVALCGGN
What is the function of this protein?
Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades.  Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors.  Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration.  Promotes resolution of inflammation and wound healing.  Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2.
What are the official names of this protein?
Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, cilium. Basolateral cell membrane. Lateral cell membrane. Cell membrane; Peripheral membrane protein. Apical cell membrane. Membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Early endosome. Cytoplasmic vesicle membrane; Peripheral membrane protein. Secreted. Secreted, extracellular space. Cell membrane; Peripheral membrane protein; Extracellular side. Secreted, extracellular exosome. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, phagocytic cup. Note=Colocalizes with actin fibers at phagocytic cups. Secreted, at least in part via exosomes and other secretory vesicles. Detected in exosomes and other extracellular vesicles. Secretion is increased in response to wounding and inflammation (By similarity). Alternatively, the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in the protein translocation from the cytoplasm into ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (By similarity). Detected in gelatinase granules in resting neutrophils. Neutrophil adhesion to endothelial cells stimulates secretion via gelatinase granules, but foreign particle phagocytosis has no effect. Displays calcium-dependent binding to phospholipid membranes (By similarity).
Protein: LPMG_ECOLI
Sequence: MEPDPTPLPRRRLKLFR
What is the function of this protein?
Makes mgtA transcription sensitive to intracellular proline levels.  Under low levels of proline this protein cannot be fully translated, and a stem loop forms which permits transcription of the downstream mgtA gene (By similarity).
What are the official names of this protein?
mgtA leader peptide, Regulatory leader peptide for mgtA.
What is the protein family that this protein belongs to?
Belongs to the MgtL family.
Protein: CHEB2_PSESM
Sequence: MPGKKISVLLVDDSAVVRQVLVAILNETPDIHVMAAASDPIFAMGKLAHEWPDVIVLDVEMPRMDGITFLKKIMSERPTPVVICSSLTQKGAETSLQALSAGAVEIITKPTTGLKNFLIESAAELVAAIRAAANSNVKNLGKRTATPVLTPASKLTADAILPAASGHSMAQTTERIVAIGTSTGGTQALEAVLTALPRVCPGIVIVQHMPEKFTASFAERLNGLSQIEVREARNNDRILPGLALIAPGGKHMMVTRSGAYYHVQVIDGPLVNRHRPSVDVLFRSVARFAGKNATGIIMTGMGDDGARGLKEMLDAGSSTVAQDEASCVVFGMPKEAIKLNAAQRIMPLQEIHQAILHR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_BRUSU
Sequence: MSVSDPLGDMLTRIRNAVGRKKTKVSTPASKLRARVLDVLQAEGYIRGYTQSEFENGKAEIEIELKYYEGVPVIREITRVSKPGRRVYVSVKSIPQVANGLGISILSTPKGVMADHEAREQNVGGELLCRIF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: HIS4_ANASK
Sequence: MLVIPAIDLIGGEVVRLEKGDFARKTVYARDPAEKAAELVRDGASLIHVVDLDGAKAGWPVNLDAVRAICAVPGAEVELGGGLRSLPDIEKVLELGVRYVVLGTAAVERLDLVRQACARFPGRVRSGIDARNGEVKIAGWLEGTGLGAAEVARRVKEAGVGLVEYTDVGRDGMFTGVDAEGAARLQAEAGVQVVASGGVAGLDDVRACRAAGLAGVIVGKALYEGRIALAEAVRAAAE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METAS_SHESR
Sequence: MPVKIPDHLPAAGILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKESKHTSIDHMNTFYRDFEDVRHKNYDGLIITGAPLGQIDFEEVTYWDHIREIIDWSQQHVTSVLFLCWAAHAGLYHLYGLNRKILQQKRSGVFVHRRTCQHFPLLRGFDDEFFAPHSRFAEMDIEELKQHPELQVLAESDEAGAYLVLSRNNRNLFVMGHPEYQKSTLNDEYHRDLAQGLNPNVPQNYYRNDDPQADAIARWHSHGSLLVSNWLNYYVYQLTPYDLSDMTAMTPWESQ
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_CHLT2
Sequence: MGAKKNLLAELREKSSEELDEFIRDNKKALFALRAEAALQNKVVKTHQFSLYKKSIARALIIKQEKKDRVHG
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RL19_YERE8
Sequence: MSNIIKQIEQEQMKQDVPAFRPGDSVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVIDSITVKRRGAVRQAKLYYLRERTGKSARIKERLNRTNTN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: CDA7L_HUMAN
Sequence: MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN
What is the function of this protein?
Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter.  Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells.  Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
What are the official names of this protein?
Cell division cycle-associated 7-like protein, Protein JPO2, Transcription factor RAM2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
Protein: MATK_CEDAT
Sequence: MDEFHRYGKEDSSWQQCFLYPLFFQEDLYAISHDHYLDGSSSSEPMEHFSFNDQLSFLTVKRLIGRIREQNHSIGLFVNCDPNPLVDRNKSSYFESVLEGLTLVLEVPFSTRSKYSVQGIKEWKSFRSIHSIFPFLEEKFPHSNYILDTRIPYSIHPEFLVRTFRRWIQDAPSLHPLRSVLYEYRNSPENLQRSIIVAPRVNTRFFLFLWNHYAYECESILVPLLKRSFQSRSSSHGSFPERTLFDRKIKHIIRISHRNSLKSIWFLKDPKIHYVRYGERSIIAIKGTHLLVKKCRYYLPIFRQCYFHLWSEPYRVCSHQLSKNCSSFPGYSLGVRMKPLLVRTKMPGELFITDLITDEFYPIVPIVSIIGLLAREKFCDISGRPISKLAWTSLTDDDILDRFDRIWRNFFHYYSGSFGRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFDSPAFSSKAVARSQRERIWHSDIPQINPLANSWQKIQDLKIKNLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MTDRP_MYCTO
Sequence: MAAEMDWDKTVGAAEDVRRIFEHIPAILVGLEGPDHRFVAVNAAYRGFSPLLDTVGQPAREVYPELEGQQIYEMLDRVYQTGEPQSGSEWRLQTDYDGSGVEERYFDFVVTPRRRADGSIEGVQLIVDDVTSRVRARQAAEARVEELSERYRNVRDSATVMQQALLAASVPVVPGADIAAEYLVAAEDTAAGGDWFDALALGDRLVLVVGDVVGHGVEAAAVMSQLRTALRMQISAGYTVVEALEAVDRFHKQVPGSKSATMCVGSLDFTSGEFQYCTAGHPPPLLVTADASARYVEPTGAGPLGSGTGFPVRSEVLNIGDAILFYTDGLIERPGRPLEASTAEFADLAASIASGSGGFVLDAPARPIDRLCSDTLELLLRSTGYNDDVTLLAMQRRAPTPPLHITLDATINAARTVRAQLREWLAEIGADHSDIADIVHAISEFVENAVEHGYATDVSKGIVVEAALAGDGNVRASVIDRGQWKDHRDGARGRGRGLAMAEALVSEARIMHGAGGTTATLTHRLSRPARFVTDTMVRRAAFQQTIDSEFVSLVESGRIVVRGDVDSTTAATLDRQIAVESRSGIAPVTIDLSAVTHLGSAGVGALAAACDRARKQGTECVLVAPPGSPAHHVLSLVQLPVVGADTEDIFAQE
What is the function of this protein?
Primarily acts as an independent SigF regulator that is sensitive to the osmosensory signal, mediating the cross talk of PknD with the SigF regulon.  Possesses both phosphatase and kinase activities.  The kinase domain functions as a classic anti-sigma factor-like kinase to phosphorylate the anti-anti-sigma factor domain at the canonical regulatory site, and the phosphatase domain antagonizes this activity.
What are the official names of this protein?
Multidomain regulatory protein MT1410, Anti-sigma-F factor MT1410, Anti-SigF factor, Protein-serine/threonine phosphatase, Serine/threonine-protein kinase.
Protein: RS3A_BOMMO
Sequence: MAVGKNKGLSKGGKKGVKKKIVDPFTRKDWYDVKAPSMFSKRQVGTTLVNRTQGTKIASEGLKGRVFEVSLADLQADTDAERSFRKFRLIAEYVQGRNVLCNFHGMDLTTDKLRWMVKKWQTLIEANIDVKTTDGYVLRVFCIGFTNKDSLSQRKTCYAQHTQVRAIRKKMCEIITRDVTNSELREVVNKLIPDSIAKDIEKACHGIYPLRDVCIRKVKVLKRPRFEISKLMELHGEGGGGKGEAGDKSERPEGYEPPVQESV
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WIF1_XENLA
Sequence: MSLTGYFAAPLCSIFLFILAHADAGQQEDSLYMWIDAHQARVLIGFEEDILIVAEGKMAPFTHDFRKAQQRMPAIPVNIHAMNFTWQATGQAEYFYEFLSLRSLDKGIMADPTVNMPLLGTVPHKATVIQVGFPCLGNQDGVAAFEVNVIVMNSEGNVILQTPQNAIFFKTCQQAKCTGGCRNGGFCNDRHVCECPDGFYGPHCEKALCMPRCMNGGLCVTPGLCICPPGYYGINCDKVNCTTHCLNGGTCFYPGKCICPSGYEGEQCETSKCQQPCRNGGKCSGKNKCKCSKGYQGDLCSKPVCEPSCGAHGTCIEPNKCQCKEGWNGRYCNKKYGSNLMNALRPTGSRNRQHTPSPKRTEDRQALPESNYIW
What is the function of this protein?
Binds to WNT proteins and inhibits their activities.  May be involved in mesoderm segmentation.
What are the official names of this protein?
Wnt inhibitory factor 1, WIF-1.
What are the subcellular locations of this protein?
Secreted.
Protein: YKZN_BACSU
Sequence: MFFGVGHAGRAQIYDKTSEKRLKHAFKPKVTDEAGGWHGVCRAELRVYAVLYLHRA
What are the official names of this protein?
Uncharacterized protein YkzN.
Protein: FABA_BRUME
Sequence: MAEQKSSYGYEELLACGRGEMFGPGNAQLPLPPMLMIHRITEISETGGAFDKGYIRAEYDVRPDDWYFPCHFQGNPIMPGCLGLDGMWQLTGFFLGWLGEPGRGMALSTGEVKFKGMVRPHTKLLEYGIDFKRVMRGRLVLGTADGWLKADGELIYQATDLRVGLSKEGSAQ
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_CALS4
Sequence: MMIRLIIHGCNGKMGKVVAKLAKENPEFEVVAGVDKNTFPLDFPVYSDLKEVKEEADVVIDFSYHEAIPNLVKEAAKRKIPVVIATTGLSEEELKTVEEASKEIPIFRSANMSLGINVLISLVKEAAKVLEGFDIEIVEKHHNMKKDAPSGTALMIADAINQVLPEKREYVYGRYTKTEQRKPNEIGIHAVRGGTIVGEHDVIFAGPNEVITISHSAQSREVFGYGALKAAKFLIGQKPGLYTMEDLVKKG
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_XANOM
Sequence: MTPTLRRKLEALAERREELQHLLSDPDVVNNNDKFRTLSRELSQLEPVAVALEDEARAKADLSAAEAMRTDPEMRELAEEEIAAAQARLEELDTQLASLLVPRDPRDDGNLFLEVRAGTGGDEAAIFAGDLFRMYARYAERQGWKVEIESDSPGEHGGYKEVVARVVGRGAYSRLKFESGTHRVQRVPATESQGRIHTSAATVAIIPEADDVEEIVINPADLKVDTFRSSGAGGQHVNKTESAIRITHVPSGVVVECQTERSQHANRDKAMKRLKAQLLDTEHSKAAAAQAQTRKLQVGSGDRSQRIRTYSFPQGRITDHRVEGLTLYDLPNIIEGDLDALIARLLHEHQADELARLSDSP
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YYZM_BACSU
Sequence: MADKDFGLNDIVEMKKPHPCGANSWKIIRMGMDIRIKCEGCSHSVMIPRREFERKLKKVLVKHEEPTS
What are the official names of this protein?
Uncharacterized protein YyzM.
Protein: MYBH_DICDI
Sequence: MTTQTKTSSPIQPSPIEQSPIQQSPIQQSPIQQSPILQSPIQRSPIQQLPIQQSPSISSTSFSNSNNDTNFNSKRLSNSIFPTSTSPVLSPLSPPLQPQPLISTSTSFNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNTPKTTISGATRSSWTKEEERLFVEAYKLYDKDNKKIQEHVKTKTILQVRSHAQKFALKLEKNGIKSLDNIDQLFNQSHAASSSHNLPSHNTPWSNEEHELFLKAIEKYGRGNWKLISTLIKSRNTLQIKNHARIYFDKISQQNGPPSKKTIIEVENNNNYNDQNNNNEQNNNNNNNNNNNNNNNNNNNSFFNGNDNGNNSSYSDNGNGNKSTSSKSDLSNTRSSGSSSSSGSSSSSSSSTISSGGSGGRSSGGSSGRSSGNSKKSSSKSKSKNPTSKPITPIQPKLILPSRNIILSSAFSTPTPTSISTFPKTPTYTTSNYKSSNNPLNRSFGSINNSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKPPTKERYLDLNIITQEEMMGCKEYFTGQISKTPDRYIKIRDKIIRQWDSFKPNYLSKTFSRNQIKDCGSDINSIGRVHQFLESIGVINFNAVGNPLNNNDYDRDNNNNNNNKNNNNNNNNNNNNNNNNNNNNNISDLSAILSSAITNRMLENRKTNNPLRKRKIFYDGQWMDQSLLNTTIEHSGNENDKINMATSSTINNVNNSKTSSSSSPTNESSKLYNFEDFSSFPSFDPFTLVECKKYNNPNEQPFTIDVSSNTMIVMDIHSHISSTEVIGMLGGKFNPDTNHITILLAIPCNSISSDIQCDMDPNSQIAAKEMVNSIGLDIVGWYHSHPNFEPIPSLRDIETQTSFQNLFATSSNNNNNNNKSMIEPFIGFIVNPYHKNGLISNFNCITITKQMDETNQYRIPYQLSTSYTPSLNNQYLYQQIDNLFEKYKSYSSRIDLKKTMENGGFTHLDKMISSISSNLILNNNSSSSNNKNNTNESDLINCDEDIIQDDQTELFLTKIKNQFKDFNNNNNNNNNNNNNNNNNNNNNNNNNNKNKNRNEGSRSRSRSRSRSRSRSRSGTRSRSRSRSLDSYSRSRSRSGGNGYVGEKTLPKKHHHQHLHNRHKSNTFNDPDLSDSYMSEVSRSSSDYYNTESSSSMSDIEDDDISEYSDTENYKSFNKNNNNNNHYNNNFLDKPVLQNKPSYQ
What are the official names of this protein?
Myb-like protein H.
What are the subcellular locations of this protein?
Nucleus.
Protein: PEPA1_PENJA
Sequence: AASGVATNTPTANDEEYITPVTIGGTTLNLNFDTGSADLWVFSTELPASQQSGHSVYNPSATGKELSGYTWSISYGDGSSASGNVFTDSVTVGGVTAHGQAVQAAQQISAQFQQDTNNDGLLGLAFSSINTVQPQSQTTFFDTVKSSLAQPLFAVALKHQQPGVYDFGFIDSSKYTGSLTYTGVDNSQGFWSFNVDSYTAGSQSGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSNAGGYVFDCSTNLPDFSVSISGYTATVPGSLINYGPSGDGSTCLGGIQSNSGIGFSIFGDIFLKSQYVVFDSDGPQLGFAPQA
What is the function of this protein?
Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates.  The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site.  Shows a broad primary substrate specificity.  Favors hydrophobic residues at the P1 and P1' positions, but can also activate trypsinogen and hydrolyze the B chain of insulin between positions 'Gly-20' and 'Glu-21'.
What are the official names of this protein?
Penicillopepsin-1, Aspartic protease, Peptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: AAAP_ANAMV
Sequence: MSRGGSPGCGRRIAEELRLAEDARLRLALLGRCIVKGSPAQVRKELRAELKAIDAEWRPVIARESLRKELDAIDAEWQHAITFWHISRAIIGSIELSKELDAIDAEWRPVIVRESLRKELKAIDAEWRPAIRLESAYRAIIGSIELSKELKAIDAETQHAVELRRALRTIEGRIELSRELKAIDAEWAPRIAQAKEIAQARESLRKELNDIDAEWAPKIAQAKEIAQAKAELAAATDALKRAADKLQALGKMDTTSTPGTDLIGVVTTAVTTTLAGTQPAPGTDLVGVATPSTALGQPAPSTALTSVAAEVATPSTALGV
What is the function of this protein?
Associates with actin filament appendages that are formed in the inclusion appendages of the parasitophorous vacuole during infection of the host erythrocyte.
What are the official names of this protein?
Appendage-associated protein.
What are the subcellular locations of this protein?
Secreted.
Protein: MYH4_RABIT
Sequence: MSSDADMAIFGEAAPYLRKSEKERIEAQNKPFDAKSSVFVADPKESFVKATVQSREGGKVTAKTEAGATVTVKEDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGDKKKEEATSGKMQGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTSDERVSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEVADKAAYLQSLNSADLLKALCYPRVKVGNEYVTKGQTVQQVYNAVGALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIAGFEIFDFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDFGMDLAACIELIEKPMGIFSILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKVEAHFSLVHYAGTVDYNITGWLDKNKDPLNETVVGLYQKSAMKTLAFLFTGTAAAEAEGGGKKGGKKKGSSFQTVSALFRENLNKLMTNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQFIDSKKASEKLLGSIDVDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQAMCRGFLARVEYKKMVERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKEEFEKTKESLAKAEAKRKELEEKMVALMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSNLQSKIEDEQALAMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDDLASNMETVSKAKGNLEKMCRTLEDQVSELKTKEEEHQRLINDLSAQRARLQTESGEFSRQLDEKDSLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSARHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKHKYEETHAELEASQKESRSLSTELFKVKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKVKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEEIDQLKRNHIRVVESMQSTLDAEIRSRNDAIRIKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQLHLDDALRGQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKVAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEAEVESEQKRNVEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISEE
What is the function of this protein?
Muscle contraction.
What are the official names of this protein?
Myosin-4, Myosin heavy chain 2b, MyHC-2b, Myosin heavy chain 4, Myosin heavy chain, skeletal muscle, juvenile.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
Protein: AROC_HERAR
Sequence: MSGNTFGTLFTVTTFGESHGPAIGCVIDGCPPGMVLSEADIQFDLDRRKPGTSRHVTQRQESDTVEILSGVFEGKTTGTPIALLIRNEDQRSKDYGNITETFRPGHADYTYWHKYGIRDPRGGGRSSARLTAPVVGAAAIAKKWLLEQYGTTFKGCMSQLGEIAIPFESWEHVPNNPFFSANASILPQLEAYMDDLRKNGDSCGARIDVVAENVPIGLGEPIYDKLDAEIAYALMGINAVKGVEIGAGFKSVAQKGTEHGDELTPDGFASNNAGGVLGGISTGQNITASMAIKPTSSIRTARHSIDKDGHPIMVETFGRHDPCVGIRATPIAEAMLALVLMDHALRHRAQCGDVKVSPPPIPASSR
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RS5_ALKOO
Sequence: MHNKRIDASQLELKEQVVDIKRVTKVVKGGRNFRFSALVIVGDENGYVGVGSGKAMEIPDAIRKGIEDAKKNLIHVPIVGTTVPHETIGIFGAGNVLIMPAKEGTGIIAGGPVRTVLELAGFKDVRAKSLGTNNAKNMVNAAINGLSQLKRAEEVAKLRGKSVEELLG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: CYH2_HUMAN
Sequence: MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP
What is the function of this protein?
Acts as a guanine-nucleotide exchange factor (GEF).  Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6.  Activates ARF factors through replacement of GDP with GTP (By similarity).  The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (PubMed:17398095).  Involved in neurite growth (By similarity).
What are the official names of this protein?
Cytohesin-2, ARF exchange factor, ARF nucleotide-binding site opener, Protein ARNO, PH, SEC7 and coiled-coil domain-containing protein 2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm. Cell projection. Cell projection, growth cone. Cell junction, tight junction. Cell junction, adherens junction. Note=Both isoform 1 and isoform 2 are recruited to the cell membrane through its association with ARL4A, ARL4C and ARL4D. They require also interaction with phosphoinositides for targeting to plasma membrane (PubMed:17398095). In differentiating neuroblastoma cells, colocalizes with CCDC120 in both neurite shaft and growth cone areas.