PharMolix/UniProtQA huggingface dataset:
Protein: FUB7_FUSO4
Sequence: MAEQVFQNFETLQLHAGYTPDPHTRSTAVPIYATSSYTFNDSAHGARLFGLKELGNIYSRLMNPTVDVFEKRIAALEGGIAAAATSSGQAAQFLTIATLAKAGDNIVASSHLYGGTYNQLNVLLPRFGIKTKFVRSGKLEDYAAAIDDQTRAIYVESMSNPDYVVPDFEGIAKIAHEHGIPLVVDNTLGAGGYYIRPIEHGADIVVHSATKWIGGHGTTIGGVIVDSGRFNWNKHSERFPEMVEPSPSYHGLKYWEAFGPATFITRIRVEMLRDIGACLSPFSAQQLLLGIETLGLRAERHAQNTEKLAKYFESSPNVSWVLWPGSESHPTYAQAKKYLTRGFGAMLSIGVKGDASAGSKVVDGLKLVSNLANVGDAKSLAIHPWSTTHEQLSEDERLASGVTEDMIRISVGIEHVDDIIADFEQSFQKAYGS
What is the function of this protein?
Sulfhydrylase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties (PubMed:25372119).  L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (By similarity).  The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (By similarity).  FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (By similarity).  Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the sulfhydrylase FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (By similarity).  Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (By similarity).
What are the official names of this protein?
Sulfhydrylase FUB7, Fusaric acid biosynthesis protein 7.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: LEPA_CHLMU
Sequence: MKPYKIENIRNFSIIAHIDHGKSTIADRLLESTSTIEQREMREQLLDSMDLERERGITIKAHPVTMTYEYEGETYELNLIDTPGHVDFSYEVSRSLAACEGALLIVDAAQGVQAQSLANVYLALERDLEIIPVLNKIDLPAAQPEAIKKQIEEFIGLDTSNAIACSAKTGQGIPEILESIIRLVPPPKPSQETELKALIFDSHYDPYVGIMVYVRVISGEIKKGDRITFMSTKGSSFEVLGIGAFLPEATLIEGSLRAGQVGYFIANLKKVKDVKIGDTVTTVKHPAKEPLEGFKEIKPVVFAGIYPIDSSDFDTLKDALGRLQLNDSALTIEQESSHSLGFGFRCGFLGLLHLEIIFERISREFDLDIIATAPSVIYKVVLKNGKTLFIDNPTAYPDPALIEHMEEPWVHVNIITPQEYLSNIMSLCMDKRGICLKTDMLDQHRLVLSYELPLNEIVSDFNDKLKSVTKGYGSFDYRLGDYKPGAIIKLEILINDETVDAFSCLVHRDKAESKGRSICEKLVDVIPPQLFKIPIQAAINKKIIARETIRALAKNVTAKCYGGDITRKRKLWEKQKKGKKRMKEFGKVSIPNTAFVEVLKME
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: OLF5_CHICK
Sequence: MALGNCTTPTTFILSGLTDNPRLQMPLFMVFLAIYTITLLANLGLIALISVDFHLQTPMYIFLQNLSFTDAAYSTVITPKMLATFLEERRTISYVGCILQYFSFVLLTSSECLLLAVMAYDRYVAICKPLLYPAIMTKAVCWRLVEGLYSLAFLNSLVHTSGLLKLSFCSSNVVNHFFCDNSPLFQISSSSTTLNELLVFIFGSWFAMSSIITTPISYVFIILTVVRIRSKDGKYKAFSTCTSHLMAVSLFHGTVIFMYLRPVKLFSLDTDKIASLFYTVVIPMLNPLIYSWRNKEVKDALRRVIATNVWIH
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor-like protein COR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CX6B1_BOVIN
Sequence: MAEDIQAKIKNYQTAPFDSRFPNQNQTRNCWQNYLDFHRCEKAMTAKGGDVSVCEWYRRVYKSLCPISWVSTWDDRRAEGTFPGKI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase polypeptide VII, Cytochrome c oxidase subunit AED, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: MIAB_GRABC
Sequence: MPMTGLLQTTLSTADQDRSGPAATTGDTPARANTKRLHVITWGCQMNVYDSARMTDVLSPLGYTAHAEPEGADMIVLNTCHIRDKATEKVFSELGRLRLLKEARAREGQPMLLAVAGCVAQAEGEQILARAPYVDIVLGPQTYHRLGGMVRRAMNGERVIETDFPPEDKFDYLPEAAAPQHGPGLAGGRTAFLTIQEGCDKFCSFCVVPYTRGAEVSRPASSVLAEARRMVRGGAREITLLGQNVNAYHGLGEDGEVWTLARLIRALADIPDLLRIRYTTSHPRDVSDDLIAAHRDIPQLMPFLHLPVQSGSDRILAAMNRRHTAEDYFRVVDRLREARPDLALSSDFIVGHPGETDEDFEDTMRLIERVGFAQAYSFKYSPRPGTPAAERDNHVPEPVMDERLQRLQALLRTQQEAFNTACIGKTVNVLLVTPGRHPGQIGGRSPWLQAVHLDAPATLIGQEVPVTITAAHTNSLSATLPDCAPHPKELTCA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y021_SYNY3
Sequence: MIWPFKTSTRKKIARIEVTGAIASGTRKAVLKALKTVEEKKYPALLVRIDSPGGTVVDSQEIYTKLKQLSEKIKVVASFGNISASGGVYIAMGCPHIMANSGTITGSIGVILRGNNLERLLEKVGVSFKVIKSGPYKDILSFDRELLPEEQSILQALIDDSYGQFVSTVAAGRNLAVEKVKEFADGRIFTGQQALELGLVDRLGTEEDARQWAATLAGLDPDKVELDTIEDPKPLVRRLTGGDSQLQTMADNLGLTESLKWCEFELSTSGQPLWLYR
What are the official names of this protein?
Putative protease slr0021.
What is the protein family that this protein belongs to?
Belongs to the peptidase S49 family.
Protein: RS11_XYLFM
Sequence: MAKQSVVKTKKRVKRVITDGVAHICASFNNTIVTITDRQGNSLFWCTSGASGFRGSRKCTPFAAQVAAEKAGRAVLDYGMKSLEVRINGPGPGRESAVRSLSNVGYKITNIIDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: EBDG_HYPJE
Sequence: MLANAIAALLLGSGIASAAGHGSPLTSKAGHRAVIPDWDLKSSSDVSKDLGGLSKPGVDTSSWYHAGTSRCTIMGCLINAGVYNDEELWYSDNLNHVNWGQFSVPWVYRHEFALSPAKGKHFLLQTNGITSKADLFFNGKQIADKEYQSGAYAGRTYDITNLAAKKNALLVQVYPTDYLYDFALGYVDWNPYPSDNGSGIWRDITIKETGSVSMGPVSVLVDIDVPVEKNPARVTVRAEAQNLESHAVEFNAAAVISGNSCSGEALKQTIKLAPGEKKLVQFTQTIKTPSIWWPKQWGDQPLYTAEVTFSVKGAVSDTAQTKFGVRKVTSFVNQFNDTQYSVNGHPFQVIGGGYGADMFLRWDSERFTRIVEYMLDMHQNTIRLEGKMEHPELYEICDEYGLMVMPGWECCDKWEAWAYNDELAIFPPPVWDANDYETANYSMIHEAAMMQPHPSVLTFLVGSDFWPNDEAVVLYANALKNAGWQTPIIASASKRGFPALLGPGGMKMDGPYDWVPPNYWYDVEPSEDRLGAAFGFGSELGAGVGTPELSSLRRFLNQSDLDDLWKNPNKNLFHMSTNASSFYNRKIYNQGLWKRYGAPTSLDDYLLKAQMMDYEATRAQYEGFGALWTASRPATGVIYWMLNNAWPSLHWNQFDYYLHPAGSYFGTKVGSRIEHVAYNYQKKEIWVINHSLYQTGSRNIKVELIDMNGKQIAKKLVQVRTKANSGFKAMDISSDINKLSSVAFLRLVLSDEKGSVLSRNVYWVTKTIDELNWDESTWYYTPVSKFVDYTPLNTLATAQVSVTTSGGKHLPGIPGSQTRTVTLENKSSVPAVFIRLTLVDSKGNDVNPVSWSDNYVTLWPHEKLQLEVGGWDGSGDKIQISGKNIKATTVKL
What is the function of this protein?
Hydrolyzes chitosan and chitooligosaccharides with retention of anomeric configuration.  Has no activity against beta-D-galactoside, beta-D-glucuronide, beta-D-mannoside, chitin, glycol chitosan, cellulose, N,N'-diacetylchitibiose and pNP-GlcNAc.
What are the official names of this protein?
Exo-beta-D-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: QSEC_ECOLI
Sequence: MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDLNEINAADRMAQTPNRLKHGHVDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIVAGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKIDVRLTLNAHSIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW
What is the function of this protein?
Member of a two-component regulatory system QseB/QseC.  Activates the flagella regulon by activating transcription of FlhDC.  May activate QseB by phosphorylation.
What are the official names of this protein?
Sensor protein QseC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IF2_TREDE
Sequence: MDIENTNKPDVILNKKSSKAADSKPESGKTDSKRKVVVKVSKTSAGKSKKPESSSEESSGGKASGKQVISVKKASSQSSKPAEASVKEKKPDERLEETKKTAPRFEDKKSDAPSAQNEKRSFDSAKKEEKQTERKKPTPSSIDSIDFASKRPNVKAGNLADSGRRNNRGQGNRPQRPGGQGQGQPGQGRRRESNFSGAQARAYSDGKKQGFRTGQGGQQGRPGDRPQNRPGFGGPRPGAAPAPIPVEKNKAQTNKKAHKAKKEIYNKKNKEEEFFEERLLNQKKKQKEKIHNIPKQIEIMESISVSELAKKMNLKASELIGKLMGMGMMVTMNQSIDADTATILASEYDCDVKIVSLYDETVIESKEDDLSELQPRPPVVTIMGHVDHGKTKTLDAIRSSNVIAGEFGGITQHIGAYTVNTHGGKITFLDTPGHEAFTMMRARGAEITDIVVLVVAADDGVMPQTIEAINHARDAKVPIIVAVNKVDKPEANVDKVKTRLSELGLMPEEWGGDTMFVEISALKKLGLDNLLDTILLQAEVLELKANYTCNAEGKVIESRIDHGRGVVATIIVQRGTLRTGDPYVAGIYSGRVRAIFNDRGEKIDEATPSMPVEILGLEGMPNAGDPFQVTDSERIARQISDKRQELKRFEDSRNVKKVTLDNLYETIHDGEILELKVIIKGDVQGSVEALKQSLEKLSTPEIRLNVIHASAGAINDSDVMLAAADSNALIIGFNVRPTPQAKLLADQEKVDIRKYTVIYKAVEEIQLAMEGMLSPDIKEQVIGMVEVRNTFKVPKIGKIAGCYVLEGVVKRNCAVHVIRDGIVVHSGKLSSLKRFKDDAKEVAAGFECGIGIEDFNDIQVDDQLEIIEMIQVARKLSDSEKYKAPEIKEEGTETDE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NLTP_CICAR
Sequence: MASMKVVCVALIMCIVIAPMAESAITCGRVDTALAPCLGYLQGGPGPSAQCCGGVRNLNSAAVTTPDRQAACNCLKSAAGSISRLNANNAAALPGKCVVNIPYKISTSTNCATIRV
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes.  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues.
What are the official names of this protein?
Non-specific lipid-transfer protein, LTP.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: UBID_SHEFN
Sequence: MSFKDLRSFIDHLEKNGELKRISYPVDPHLEMTEIADRVLRSGGPALLFENPTNHTMPVLVNLFGTPKRVAMALGKDDPLALREVGELLAFLKEPEPPTGFKDAIAKIPMYKQALNMPPKTVRNPPCQQVVKTGDEVDLTSLPIQHCWPGDVAPLVTWGLTITKGPRQKRQNLGIYRQQLLSKNKLIMRWLDHRGGALDFKDFKQLHPGERYPVVVALGSDPVTILGAVTPVPDSMSEYAFAGLLRGERTEVCKAISCDLEVPATSEIILEGYIDPEETAVEGPYGDHTGYYNETDSFPVFTVTHITHRKDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIIDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVVVDDDVNCRDWQDVIWAITTRMDPIRDTMMVDNTPIDYLDFASPVAGLGSKMGLDATNKWPGETTREWGTPIVMDEKTKQRIDQIWDDLGIQDMPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SEC72_SCHPO
Sequence: MVAKQESVVAPQVDVSKWSGKELELGKKVNEYAKSLATFKYPFFIPPPYPPAKPNMALSTQVNKMKQTANEAFKRKKYEEAKKLYGLALQLALNRCTWEPSILTREEASVMLCNRAAAEIALSQFPEALADANAALKIRNNYGKCYYRKAKALEAMHRIEEAKQVVRDGLILAEPVTRNELVALWASYTEKD
What is the function of this protein?
Acts as non-essential component of the Sec62/63 complex which is involved in SRP-independent post-translational translocation across the endoplasmic reticulum (ER) and functions together with the Sec61 complex and bip1 in a channel-forming translocon complex.  A cycle of assembly and disassembly of Sec62/63 complex from sec61 may govern the activity of the translocon.  sec72 may be involved in signal peptide recognition for a defined subset of leader peptides, or may increase the efficiency of unusual or 'difficult' secretory precursors to the translocation pore, it may be that this protein binds charged leader peptides to the membrane until they engage the translocation apparatus (By similarity).
What are the official names of this protein?
Translocation protein sec72.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CC107_MOUSE
Sequence: MEGAGPVLSILGLLLVSAPFGVLGERPSADLGAHPERGSQVSPGTTEPRRQPPPKDQRERARAGSLSLGALYTAAVVAFVLFKCLQGPDEAAVLREEKNKKKSSQSEQQLVQLTQQLAQTEQHLNHLMTQLDPLFEQVTTLVGTQRELLDTKLKTIHHLLQDCQPGTGVEVPEPEASIPFTEDLGKEDQEAGNSQAWEEPITWSPETRNLAPSWEVEQGLRRRWHKTVTKGPAVNGEQPLKV
What are the official names of this protein?
Coiled-coil domain-containing protein 107.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CYB_MONDO
Sequence: MTNLRKNYPLMKIINHSFIDLPAPSNISAWWNFGSLLGMCLIIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLYKETWNIGVILMLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIILALVIVHLLFLHETGSNNPTGINPNSDKIPFHPYYTIKDALGLILMLLILMSLAMFSPDMLGNPDNFTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASLLILLIIPLLHTSKQRSLMFRPISQIMFWLLVANLLTLTWIGGQPVEQPFIIIGQLASTLYFSLIIIFMPLAGMYEDHLLEPKFP
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TX14A_MYRGU
Sequence: MGKVFFFVLMIAIIGSTFLIEEALGSLVGCPRPDFLPSWNRCKSCVCKNNKLKCPKILKGSLLKTAA
What are the official names of this protein?
U-myrmeciitoxin(01)-Mg4a, MIITX(01)-Mg4a, U-MIITX(01)-Mg4a.
What is the protein family that this protein belongs to?
Belongs to the ant myrmeciitoxin-01 family.
What are the subcellular locations of this protein?
Secreted.
Protein: T184C_PONAB
Sequence: MPCTCTWRNWRQWIRPLVAVIYLVSIVVAVPLCVWELQKLEVGIHTKAWFIAGIFLLLTIPISLWVILQHLVHYTQPELQKPIIRILWMVPIYSLDSWIALKYPGIAIYVDTCRECYEAYVIYNFMGFLTNYLTNRYPNLVLILEAKDQQKHFPPLCCCPPWAMGEVLLFRCKLGVLQYTVVRPFTTIVALICELLGIYDEGNFSFSNAWTYLVIINNMSQLFAMYCLLLFYKVLKEELSPIQPVGKFLCVKLVVFVSFWQAVVIALLVKVGVISEKHTWEWQTVEAVATGLQDFIICIEMFLAAIAHHYTFSYKPYVQEAEEGSCFDSFLAMWDVSDIRDDISEQVRRVGRTVRGHPRKKLFPEDQDQNEHTSLLSSSSQDAISIASSMPPSPMGHYQGFGHTVTPQTTPTTAKISDEILSDTIGEKKEPSDKSVDS
What is the function of this protein?
Possible tumor suppressor which may play a role in cell growth.
What are the official names of this protein?
Transmembrane protein 184C, Transmembrane protein 34.
What is the protein family that this protein belongs to?
Belongs to the TMEM184 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RAF2_SCHPO
Sequence: MPPVRAEKKRKTDLIEQVCVTNKAGELVDLEDVLEYGPYSLTGILSSEKDEQEPLFDESIVLGYSIKISPVWTYNLKDVPEKETMSIWIVTPQRRYGILSPSSEYKAIYEQISEKNRLFYLIKTKFKDDMISGTLEDYDNYIEVLKEKLELPSCFQAILLVQKHIRFLLTQMVATSSLHVWSESPFFIRIRSSYEHLILQINKNIYNARQERKKSKLSSNNPSDNNTTMKSSLNQALTLINLPEQPFSISSPTATPQLGVVKRTSPLRFPLNDIWLSGLRIVDPNIESISLWKRIQVSTSPKHQRYISLQEVCSVIAQQLQITNLEALNKLSSHGETLLQIMHTAFTWRGTKLFNDIKHAIGFRSSVQQARSQFRGYCYDYLFMHCNNGEKTSLHLLRTLICMKLDFSNAQLAAKILFHFLLFDIGSGLSGSDYTYEQYINHSAVAFSFTEEIFEKNFVTVLPDFVKLFSISFGYWPAFSFYDELLKLLRNKYPKVYSSTPNLCDQVWLDRTNLFPCNRSTRSTLPYRPTKLLDLASASSCLSKKETDFKQDTGLYSYNLEKVEALKVSPDLQTGIWSCPVQNCLYFAVCDNPYKPSQVIYDHLLGHVDSKFIFKTPSNSVRSFTNKLEHIMYNIN
What is the function of this protein?
Component of the Clr4 methyltransferase complex (ClrC) which contributes to the establishment of heterochromatin by specifically methylating histone H3 to form H3K9me (PubMed:16024659, PubMed:16040243, PubMed:16157682).  ClrC preferentially ubiquitylates H3K14 and ClrC-mediated H3 ubiquitination promotes clr4 methyltransferase activity for the methylation of H3K9 (PubMed:31468675).  H3K9me represents a specific tag for epigenetic transcriptional repression by recruiting swi6/HP1 to methylated histones which leads to transcriptional silencing within centromeric heterochromatin, telomeric regions and at the silent mating-type loci (PubMed:16024659, PubMed:16040243, PubMed:16157682, PubMed:18345014).  Has a role in both mitotic and meiotic chromosome segregation (PubMed:16040243).
What are the official names of this protein?
Rik1-associated factor 2, Cryptic loci regulator 7, De-localization of swi6 protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus. Chromosome.
Protein: HYBG_ECOL6
Sequence: MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Involved in the biosynthesis of the Fe(CN)(2)CO cofactor.  HybG delivers iron-bound CO(2) to HypD where reduction to CO probably occurs.  In complex with HypD, accepts the cyanide ligand generated by HypF and HypE, and also coordinates the carbon monoxide ligand.
What are the official names of this protein?
Hydrogenase maturation factor HybG.
What is the protein family that this protein belongs to?
Belongs to the HupF/HypC family.
Protein: RL21_STRPQ
Sequence: MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEVTFNEVVLVGGDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: RL14_SHESH
Sequence: MIQMQSTLDVACNSGARRVQCIKVLGGSHRRYAGIGDIIKVSVKEAIPRGKAKKGDVYSAVVVRTKKGVRRPDGSVIRFDRNAAVLLNANNAPIGTRIFGPVTRELRNEQFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RRG9_DEBHA
Sequence: MFRVLIPSRKLVPGCGGFMGGIARIQAYSTKKDKSEEIFKTKIQQREKEAQQKLPEWTKRDEAIRNRYGEWNPTHRLSRQQIQDIRNIKDKMPHMKTIELANHFKISPEAIRRILKSTWVPSDSEEERIRLRGEKRKDESLVHKKEMMNDIELARKRLTYGKSVTMGGINVPRSGGRKGKNLRNTFSTDGKVNFDSNNSHGYYNRKGKTKAFKRKPYVENVGDIID
What is the function of this protein?
Required for respiratory activity and maintenance and expression of the mitochondrial genome.
What are the official names of this protein?
Required for respiratory growth protein 9, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RRG9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SYE_STRR6
Sequence: MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIEDTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKAYKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAVNESGIYKWHDMVKGDIEFEGGNIGGDWIIQKKDGYPTYNFAVAIDDHDMQISHVIRGDDHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYLPEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKNADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEAEREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRIAVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PR38B_HUMAN
Sequence: MANNSPALTGNSQPQHQAAAAAAQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHKNKDETV
What is the function of this protein?
May be required for pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor 38B, Sarcoma antigen NY-SAR-27.
What is the protein family that this protein belongs to?
Belongs to the PRP38 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TDH_STRMK
Sequence: MKALVKREAAKGIWLEEVPVPTPGPNEVLIKLEKTAICGTDLHIYLWDEWSQRTIKPGLTIGHEFVGRVAALGSAVTGYEIGQRVSAEGHIVCGHCRNCRGGRPHLCPNTVGIGVNVNGAFAEYMVMPASNLWPIPDQIPSELAAFFDPYGNAAHCALEFNVIGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVNDFRLKLAADMGATRVVNVANQSLKDVMKELHMEGFDVGLEMSGNPRAFNDMLDCMYHGGKIAMLGIMPKGAGCDWDKIIFKGLTVQGIYGRKMYETWYKMTQLVLSGFPLGKVMTHQLPIDDFQKGFDLMEEGKAGKVVLSWN
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.