PharMolix/UniProtQA huggingface dataset:
Protein: FUS8_GIBF5
Sequence: MDSKPLEYLLGLNSDGSVKKVSEVFENLTVTNTVCAFIALFIIVPRVFDFLRNLFSPVISIPGPLINKFSPWPLEIATFKGKSHRFARALHRKYGPIVVLAPGMISIGDSQEIKRIIQSEDWAKSEAIYGNFRQDFHRPTLLAFTEKKAYSRRKRMLSSMFGIRYIRSLEPLMKSCVDAGVAHLNKLCDNPSKSTVINLQHFIHGLAIDTIGVTTFGGSFHVVENGSHPLPSRLKAGMKISAVMQLIGWIKYIPFLPKRDPYIEKFTFDIVDKRRKEAGAVKYQDLLQHLVDVCDDSPGSEFRTSDVQDESVILLAAGSETTANAELFTVIQLLKHPEVMKKLIAEVDKWYPPSEPDRVTECAYSQTGMTYLQACIDETMRLIPGQATGSPRETSKQESLLGYKIPRGTTVFPNTQEAHLDGSIWEQPEKYIPERWLEIYSQNQTSAMPYWPFSAGSRICVGKNFAFQEMHISLTTLLRKFTFEYVPGQDETTVFRIAQQLETDSYKVRVKKRF
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:23932525).  Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (PubMed:23932525).  The roles of the other FUS members are yet undetermined (PubMed:23932525).  The fusarin C synthetase FUS1 is responsible for the condensation of one acetyl-coenzyme A (CoA) unit with six malonyl-CoA units and the amide linkage of the arising heptaketide and homoserine, subsequently releasing the first intermediate, prefusarin, as an alcohol with an open ring structure (PubMed:23932525).  The cytochrome P450 monooxygenase FUS8 participates in multiple oxidation processes at carbon C-20 and is able to use the FUS1 product as substrate, resulting in formation of 20-hydroxy-prefusarin (PubMed:23932525).  This reaction seems to be essential before the 2-pyrrolidone ring closure can be catalyzed by FUS2, generating 20-hydroxy-fusarin (PubMed:23932525).  FUS8 is able to further oxidizes carbon C-20 after ring closure, resulting in the formation of carboxy-fusarin C (PubMed:23932525).  As the last step, FUS9 methylates the hydroxyl group at C-21 to generate fusarin C (PubMed:23932525).  Fusarin C can then rearrange to epi-fusarin C, the (z)-isomers, and fusarin A and fusarin D (PubMed:23932525).
What are the official names of this protein?
Cytochrome P450 monooxygenase FUS8, Fusarin biosynthesis protein 8.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MCHX_ECOLX
Sequence: MEFATNRVTVNDSRSALSSTLLLSLIMSATLLEYSLSMT
What is the function of this protein?
Required for microcin H47 production.  Possibly involved in a regulatory loop modulating its own expression and that of MchI and MchB.
What are the official names of this protein?
Protein MchX.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: KITH_LACJO
Sequence: MAQLFFRYGAMSSGKSIEILKVAHNYEAQGRKIALMTSNVDDRSGVGTVASRIGLHRKAVPISEDLDLFNYVSELNKSDVESGNGRVACVLIDEAQFLKRHHVLECAKIVDELKIPVMAFGLKNDFQNHLFEGSENLLIFADKVEEMKTICHYCGHKATMNLRINSGKPVYEGEQVQIGGDESYYPVCRFHYFHPNKQR
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4WA_SINFN
Sequence: MSEPFFRPGSGPAPGHPTAEPWRRRKRWYSPSDGRAGTARSHLPQRSTSHDGVCSRICAFVLCMVALQFLMTSAMAADESPLREAEVANFMLGNGMEVVVIPDHRAPIVTQMIWYKVGNADEPPGKSGIAHFLEHLMFKGTKKHPSGEFSAKIAEIGGEENAFTGSDYTAYHQTVTPESLRTMMEFEADRMRHLVLTDAVIVPERDVILEERRWRVENDPEQLLEEEMQATLYQNHPYRIPTIGWMHEMEQLNREDALKFYDRYYAPNNAILVVAGDVDAGRVRQLADETFGTLPRGPDLPARVRPQEPEQNTKRIVALTDPRVTVPSFQKSWVTTSYGTAEQGEAEALDILSEILGGGTRSRIYQELVVKQAIASSGGAYFNGRSLDPSSFTVFGSPRGEAKIEEVEDAIDAEIRKIIEFGITDVELEKAKNRFVRSIIFARDSQSGMAGIYGAALATGDTAHDVEAWPLRIRAVKAAEVQAAARKYLSPDRSVAGYLLPRESATSGDKSR
What are the official names of this protein?
Uncharacterized zinc protease y4wA.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RF1_METS3
Sequence: MAEVSSKELYKFKKTLKELSEKKGRGTELVSVYIPHDKQISDVGKQMRDELGQSANIKSKQTRKNVQSAIEVIMQRIRLFKAAPENGLVLFVGMIPRGGPGTEKMETYVFEPPEPITTYWYQCNNEFFLEPLEYMIEERETYGLAVIDRKEATIATLRGKKVNILNHLTSGVPGKHKAGGQSQRRFDRVIDLAAHEFKKRIGEHMNEDFLALEELEGVIIGGPGFTKEEFVKGDYLNYEIKDKIIATVDTSYTGEFGIREVIDKSADILNDLDVMQEKKVVQKFLHELVKDKGLASYGEREVRTNLIMGAVDTLLLSEDLTAMRKVFKCPSCGNEEEITVKSQSEADKLEKPCSNCGEILKEESSQTLIEDFVEKAEEMNSEVELISTETEEGMQLLRAFGGVAAILRYHVG
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGUA_ARATH
Sequence: MEESRESPAEHGYYMPAEWDSHAQTWIGWPERQDNWRHNALPAQRVFADVAKAISKFEPVTVCASPAQWENARKQLPEDIRVVEMSMNDSWFRDSGPTFIVRKRPVKLSSLNRNIAGIDWNFNAWGGANDGCYNDWSHDLLVSRKILALERIPRFQHSMILEGGSIHVDGEGTCLVTEECLLNKNRNPHMSKEQIEEELKKYLGVQSFIWLPRGLYGDEDTNGHIDNMCCFARPGVVLLSWTDDETDPQYERSVEALSVLSNSIDARGRKIQVIKLYIPEPLYMTEEESSGITQDGEAIPRLAGTRLAASYVNFYIANGGIIAPQFGDPIRDKEAIRVLSDTFPHHSVVGIENAREIVLAGGNIHCITQQQPAEPTSVAENGH
What is the function of this protein?
Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.
What are the official names of this protein?
Agmatine deiminase, Agmatine iminohydrolase, Protein EMBRYO DEFECTIVE 1873.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: SFXN5_RAT
Sequence: MADTATTASAASAAASASNASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTEKRLREAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIVVGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVGLNVLVQKANKFTPATRLLVQRFVPFPAVASANICNVVLMRYGELEEGIDVLDADGNLVGSSKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVHSLVCLAAFGLALPLAISLFPQMSEIETSQLEPEIARATSSRTVVYNKGL
What is the function of this protein?
Mitochondrial amino-acid transporter (By similarity).  Transports citrate (PubMed:12150972).  Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity) (PubMed:12150972).  In brown adipose tissue, plays a role in the regulation of UCP1-dependent thermogenesis probably by supporting mitochondrial glycerol-3-phosphate utilization (By similarity).
What are the official names of this protein?
Sideroflexin-5, Tricarboxylate carrier BBG-TCC.
What is the protein family that this protein belongs to?
Belongs to the sideroflexin family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: APOE_PTEGI
Sequence: MKFLWAALVVTLLAGCQADVEEEVKLGQEPDRWQAKQPWEQALGRFWEYLRWVQTLSNKVKEELLNSQVTEELKLLIEETMKEVKAYKEELEKQVGPIAQETQARLSKELQAAQARLESDMEDVRTRLAQYRSEAQAALGQNTDDLQGRLASHLRKLRKRLLRDAEDLQKRLAVYQAGTREAAERGVSAVHERLGPLMMEGPLQAIPPSQQLRERAEAWGQKVRGRLESVGSQARDRLDDMRDQMEELKAKVEEQASQVRLQAEAFQTRLKSWFEPLVQDMQRQWASLVEKVQSSLGISPSTKPSKTK
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: DNAK_LEIXX
Sequence: MSRAVGIDLGTTNSVVSVLEGGEPTVIANAEGFRTTPSVVAFTKDGEVLVGETAKRQAVTNVDRTLSSVKRHMGTDWKTQEIDGKKYTAQEISARILQKLKRDAEQYLGDTVTDAVITVPAYFNDAERQATKEAGEIAGLNVLRIINEPTAAALAYGLDKGKEDELILVFDLGGGTFDVSLLEVGKDDDFSTIQVRATAGDNRLGGDDWDQRIVEWLIKRFKESTGVDASTDKIAKQRLKEAAEQAKKELSSSMSTSIQLPYLSLTENGPANLDETLTRAQFEQMTSDLLDRTKKPFKDVIKEAGIEVSDIAHVVLVGGSTRMPAVSELVKQETGGQEPNKGVNPDEVVAVGAALQAGVLKGERKDVLLIDVTPLSLGIETKGGIMTKLIERNTAIPTKRSETFTTADDNQPSVAIQVFQGEREFTRDNKPLGTFELTGIAPAPRGIPQVEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSSLPKDDIERMVREAEEHAAEDKKRRESAETRNQAEQLVYSIEKLIKDNEEKLPEDIKNEVQGDVDALKAALAGEDDEAVKTAYDKLNESQQKLGQAIYSAAQAAEAPAAAAGEEASAPSSSTGEEDVIDAEVVEDEEKKQQ
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HXABB_DEVAE
Sequence: MMDFDERVPVGSNMYLPGCTYYVSGTDFSSLPPFLPQTPSSCPMTYSYSTSSLPQVQSVREVSFRDYAIDTSSKWHSRGNLPHCYATEDMVHRDCLSNPGTLGDMLSKNNSVLYHSNTNHASNMYGNVGRNGVLPQAFDQFFETTYGNVENQPTDHPVDRTASKAPPPAESGSDSCRGTDETERCEETSSPEPSSGNNEEKFSGSSNGQKTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRDRLQYYTTNPLL
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A11b.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TIG_TERTT
Sequence: MQVSIETTSGLERRLTVGIPAEIIDQEVEKRLKQAAKTVRINGFRKGKVPFKVVKQRFGEGVRQEVLGDTIQRSFYDAVRQESVRPAGQPSIEPKQMDEGKDVEYIATFEVYPEVELKELDNIEITRYDAEITDADIDKMVETLQKGQSSWEPVKRKSKKGDKVTIDFLGKIDGEAFDGGEAKGHQLELGSGSMIPGFEKGITGMKAGETQPINVTFPDDYHVEDLRSKDAEFEITVHEVLGEKLPKLDEEFYAKFGVTEGGEEKFREEVKSNMEREKQRAIKAKVKEQVMNALLESNSVDLPAALVQSEIGAMRQQMVQQYGQSAQNLDLQALLPDDMFKAQAERRTALALIVSEVVKKYEVKADKDIVRSLIEEAASTYEDPQEVINYYYSNEQLLANVEAAALEEKVVELLLEKATVTDATVSYDEVIKPQEPQAEEA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ADHS_METMP
Sequence: MEMFDNIKNVGKLIRLERIFDKKSEKTVIIPMDHGVSSGPLDGIKDMRITTNAVADGGANAVLGHKGLVRHGHRGYGRDIGLIIHMSAGTSISPDPNKKVIVTTVEDAMRMGADAVSLHVNVGAESDFEMYRDLGLISETCEHWGMPLIAMMYPRGPKIKDEKDPEVVAHAARLGAELGADIIKTNYTGDPDTFKEVVKGCPAPIVIAGGPKTNTDEEFLQMVKDAMHAGGKGVASGRNVFQHKDVKGITSAICKIVHEDVEVEEALKEIKI
What is the function of this protein?
Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH) (Probable).  Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids and which is also a precursor for the biosynthesis of p-aminobenzoic acid (PABA) in M. maripaludis.  Does not possess fructose-bisphosphate (FBP) aldolase activity.
What are the official names of this protein?
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase, ADH synthase, ADHS, ADTH synthase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.
Protein: VAPC8_MYCBO
Sequence: MIVDTSAIVAIVSGESGAQVLKEALERSPNSRMSAPNYVELCAIMQRRDRPEISRLVDRLLDDYGIQVEAVDADQARVAAQAYRDYGRGSGHPARLNLGDTYSYALAQVTGEPLLFRGDDFTHTDIRPACT
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase.
What are the official names of this protein?
VapC ribonuclease Mb2780c, RNase Mb2780c, Toxin Mb2780c.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: CLPX_RIPO1
Sequence: MSKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVELCNEILDEELMDAPAAAVAGGGSPKPDDSRPKRRPSRERLSFNQIPKPREIKKYLDEYVIGQDEAKKVLSVAVYNHYKRLSLASKPGEETSEDHIELQKSNILLMGPTGSGKTLLAQTLAQILDVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTIANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLDKVIEQRRGKKSMGFIRPGDTNQSKEKRAADLMQQAEPDDLVKFGMIPEFVGRIPVMASLEPLDEETLIAILTQPRNALVKQYQKLLKMDNVQLEFNKDAVRAIAQEAYRRKTGARALRGIVEELMLDVMYELPSRKDVQRCLITKEMVEQRSTADLLVHPSSLPTPESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: AROK_BRUAB
Sequence: MSGTNKQTNLHRQTETIRQLLGSKVVVLVGLMGAGKSTIGRKVANMLNLPFKDADTEIETVSRMTVAELFEAYGEVEFRDLERRVILRLLDDGPMVLATGGGAYMNAETRAAIAEAGISIWINADLDVLMERVSRRQNRPLLRNSDPRGVMQRLMDERYPVYALAELHLMTRDEKKEVIAAELIEVLAAHLEKEQAASAG
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLN2_ALLSA
Sequence: MICLVILTCIIMSNSFVNNNNMVQAKMTWTMKAAEEAEAVANINCSEHGRAFLDGIISEGSPKCECNTCYTGPDCSEKIQGCSADVASGDGLFLEEYWKQHKEASAVLVSPWHRMSYFFNPVSNFISFELEKTIKELHEVVGNAAAKDRYIVFGVGVTQLIHGLVISLSPNMTATPDAPESKVVAHAPFYPVFREQTKYFDKKGYVWAGNAANYVNVSNPEQYIEMVTSPNNPEGLLRHAVIKGCKSIYDMVYYWPHYTPIKYKADEDILLFTMSKFTGHSGSRFGWALIKDESVYNNLLNYMTKNTEGTPRETQLRSLKVLKEIVAMVKTQKGTMRDLNTFGFKKLRERWVNITALLDQSDRFSYQELPQSEYCNYFRRMRPPSPSYAWVNCEWEEDKDCYQTFQNGRINTQSGVGFEASSRYVRLSLIKTQDDFDQLMYYLKDMVKAKRKTPLIKQLFTDETETASRRPFI
What is the function of this protein?
Able to cleave the C-S bond of sulfoxide derivatives of Cys to produce allicin, thus giving rise to all sulfur compounds which are responsible for most of the properties of garlic, such as the specific smell and flavor as well as the health benefits like blood lipid or blood pressure lowering.
What are the official names of this protein?
Alliin lyase 2, Alliinase-2, Cysteine sulphoxide lyase 2.
What is the protein family that this protein belongs to?
Belongs to the alliinase family.
What are the subcellular locations of this protein?
Vacuole.
Protein: MNHC1_STAAR
Sequence: MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit C1, Mnh complex subunit C1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GSPN_PSEAE
Sequence: MIPRRSSDITIKTRSDVLPFSGASSRWLQRYAPALLAVALIIAMSISLAWQAAGWLRLQRSPVAVAASPVSHESIRSDPTRLARLFGTSAQDPNAPPPATNLDLVLKGSFVQSDPKLSSAIIQRQGDKPHRYAVGGEISDGVKLHAVYRDRVELQRGGRLESLPFPHRSGGLLASADDITSENDSIEQLQSLQDENAAALRERLDALRQQMEATPIAEPAEEDSSEPTTTPTESD
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity).  Required for the translocation of a variety of enzymes across the outer membrane.
What are the official names of this protein?
Type II secretion system protein N, T2SS protein N, General secretion pathway protein N, Protein XcpP.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: TRPB_MYCBO
Sequence: MTDLSTPDLPRMSAAIAEPTSHDPDSGGHFGGPSGWGGRYVPEALMAVIEEVTAAYQKERVSQDFLDDLDRLQANYAGRPSPLYEATRLSQHAGSARIFLKREDLNHTGSHKINNVLGQALLARRMGKTRVIAETGAGQHGVATATACALLGLDCVIYMGGIDTARQALNVARMRLLGAEVVAVQTGSKTLKDAINEAFRDWVANADNTYYCFGTAAGPHPFPTMVRDFQRIIGMEARVQIQGQAGRLPDAVVACVGGGSNAIGIFHAFLDDPGVRLVGFEAAGDGVETGRHAATFTAGSPGAFHGSFSYLLQDEDGQTIESHSISAGLDYPGVGPEHAWLKEAGRVDYRPITDSEAMDAFGLLCRMEGIIPAIESAHAVAGALKLGVELGRGAVIVVNLSGRGDKDVETAAKWFGLLGND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: LALBA_PAPCY
Sequence: KQFTKCELSQNLYDIDGYGRIALPELICTMFHTSGYDTQAIVENNESTEYGLFQISNALWCKSSQSPQSRNICDITCDKFLDDDITDDIMCAKKILDIKGIDYWIAHKALCTEKLEQWLCEKE
What is the function of this protein?
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme.  This enables LS to synthesize lactose, the major carbohydrate component of milk.  In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
What are the official names of this protein?
Alpha-lactalbumin, Lactose synthase B protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ITPA_USTMA
Sequence: MSNPTLTFVTGNANKLREVQQIFSLTPNFPYELTNKDLDLPEIQGTTRDVAQAKCAAAAKALGGACITEDTALGFHALGGLPGPYIKDFMKTIGHDGLNKMLDGFEDRTASAICTFAYCAGPDEQVHLFEGRTEGVIVPPRGPTHFGWDPILEIKGTGLTYAEMDPKQKNTLSHRYKALTLLQDYLVGLSKQN
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YL193_MIMIV
Sequence: MIPVTILTISHFNRSDFLKILSKCVKKQDYPNIKEWVIIDTSFVGYYKTQQDLSSLIEEFRNDTDLPAIVYNKATTNNIGGWRNEGNSYVSGDIIVCMDDDDYYPPMRISHAVEKLKDKSSLIAGCDKMYFFDIHYNEFYLFNGFGQTHSTNNCMAYWREYINSHTYDETVTHAEETKFTNDFKEPMIQLETDKTVLQFSHNINTYDKKHIIHTNHVLPKEVKYITLLNKSVREFINNDEIYNDYETIFNKLRQPVKSEYDIVYYLGLCPQWSPLQKNLGGSEQAVIYLATEWAKQGKKVAVYGNLIHFGTIDGVEYIDFKKFQFWNQYDILILWRLYGFYPHINYNLKARKLLVDIHDNIPEPYELLMRYKNKITHWMVKSQYHKSYIEAITGQELSNGVIIPNGVRIKEFQKSVVETRNQFRMCYCSCYVRGLHRILSGIWPIIHQLEPRAELHVYYGMDLIVDENYKKELKQLLSQPGVMDHGKQPIEIINREKHMSNFHFYYSDYPGETDCITIKESLVAGCIPIISDFGVFKERHGVHLKWLPNTADFNQNIAHIVIELLHDTNIQEQLRKELVNSSTIISWEKIANEWINLFETP
What are the official names of this protein?
Uncharacterized glycosyltransferase L193.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
Protein: PHEA_NEOHI
Sequence: MKSVITTTISAADAAGRFPSSSDLESVQGNIQRAAARLEAAEKLASNHEAVVKEAGDACFAKYSYLKNPGEAGDSQEKVNKCYRDVDHYMRLVNYCLVVGGTGPVDEWGIAGAREVYRTLNLPTSAYVASFAFARDRLCVPRDMSAQAGVEYAGNLDYLINALC
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
R-phycoerythrin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the periphery of the phycobilisome rod.
Protein: SYC_THEKO
Sequence: MGIKIYNTLTRQKEEFKPLREGEVRMYVCGPTVYDYTHIGHARTYIAFDVIRRYLEHKGYTVLMVMNFTDIDDKIIKRANETGEDPKELAEKFLKYFLEDMKALKVKPADIYPRVTEHIQDIIDFIRKLQEKGYAYEGSDGVYFEVRKFKDYGKLSKVKLEDLVKGARVEPGEGKKNPEDFALWKKAKPGEPKWESPWGEGRPGWHIECSTMSTKYLGESFDIHGGGSDLIFPHHENEIAQTEACTGHEWVRYWMHTGFLMVNGEKMSKSLGNFVTIREALERYDPEVIRLFVLQRHYRSPLDYTEEGLEHAKNNLERLYNTLENIRVAMERAEISFKWGEEEFEAYEAIRDGRKKFYDAMDDDFNTAEALKAVFEVSNAINRYLTQVEKPKESILRKAWEFFKMVSEVFGIFEDYFREQKAGEEEALIKLLIDVRAQLRKERKFDLADKIRDELRNLGIQLEDTPQGTVWKRIKV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPF_LEGPA
Sequence: MGIKFTKMHGLGNDFIVLDGVNQSIQLTVKQIQKLANRHTGIGFDQCLLIESSQTEGIDFNYRIFNADGQEVGQCGNGARCIALFARYYGLTAKNKLTVATKTTLMDLIINEDNSVSVNMGVPRLAPGEIPLLADRQSPEYSLELNNGNTVNLHAISIGNPHAVLLVENIDTAPVNSLGQQISFHPQFPEQVNVGFMQIVNHEKINLRVYERGCGETIACGSGAVAAAAIARLFYNLSDKITVHLPGGDLCIQWPCPTAPIILTGPAAFVYEGTLLS
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LFTR_BURTA
Sequence: MVPWLGPDDPFPSVERALGAASGAPGLLAASADLLPSRLIDAYRRGIFPWYSDGQPVLWWSPDPRMILVPAEFRISATFRKTLKRVLREPRWEIRVDCDFAGVMRACAQAPRRGQRGTWITAEIIDAYSSLHRAGDAHSIETWLDGRRVGGLYGVSFGGMFFGESMYADVSDASKIALAALVAHLREHRVVMIDCQQNTSHLASLGGREIARKAFVAHVRRAVAEPPISWRFDKTVVAGLLGQAASATAADAFDR
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.