PharMolix/UniProtQA huggingface dataset:
Protein: RRP42_SULIL
Sequence: MSSTPSNQNIIPLIKKESIVSLFEKGTRQDGRKLTDYRPLSITLDYAKKADGSALVKLGTTMVLAGTKLEIDKPYEDTPNQGNLIVNVELLPLAYETFEPGPPDENAIELARVVDRSLRDSKALDLTKLVIEPGKSVWTVWLDVYVLDYGGNVLDACTLASVAALYNTKVYKVEQDSNGFRVNKNEVVGKLPLNHPVVTVSIAKVDKYLIVDPDLDEESIMDTKVSFSYTPDLKIVGIQKSGKGSMSLQDIDQAENTARLVAVKLLEELKKQLGI
What is the function of this protein?
Non-catalytic component of the exosome, which is a complex involved in RNA degradation.  Contributes to the structuring of the Rrp41 active site.
What are the official names of this protein?
Exosome complex component Rrp42.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp42 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTC5_TALMQ
Sequence: MGAGQSTGGLESPSTPEQLSVLLAERFATKCFTPLELTHFKDNFYSRALDQAGFRYWNEKILSDFLSIPDGIYTNEKDGGHDGRLDAGPVIFRMVSYLGAFPFQKTLAPSVLTFDAMVKVVVLLTERYGKVLRRGRKDRVKLLFGSLADVGRPVRQEEHNDEGSSSTKTEEAKQSSSHAQGFSVDVSVNDEYDEYEDDDDLALAALESLDAIEVFKHDQRIDGAVYEARISVDTFRRLLMLLLAIAPLKPLESVTKYTFNLSSEEQAAVKREADTIIASFTEEEIRDGIRYKSFAKTVSISLPHLFDPLTPLFEHLLFSKNLDLSRKQTGASNASPESHPPIQTPINEEEQPTTIMLPGSFESAILTPSLVSHLSFFLPASSGQNLYRSDIRLHPVFSTVAHGESLTSFQHNVFTWQAPSILIVQGAAPGSSGTPDELITLGAYIPQPWKPSSSSWETSQSLNDKSRLPYLFQIHPKHSVLPGNPSLLSTREQSSATTPTVYFSTTTGIAIGCEIPASAQQQRTHYGPGVPSPREHLQHHRQSSGGNSIHKQQQQGPIPHGAGSLIIDSGLETAQLHISYLTGSTGVFTRAVPPILPTTTHIDIYNLEIWGIIEPDPLIAAVGGDTISRDAISQQRAAWQFDAREAERRKCINVKLGSGTDSEYQNARALLEMAGIIGDQAHQRSGGSV
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_LIGS1
Sequence: MEGKFITFEGIDGSGKTSVLKGVIEHLNDKRIDNYIWTREPGGNRISEAIRKIILNVEYTEMDARTEALLYAAARRQHLVDTVLPALNEGKLVLCDRFVDSSVVYQGVARDIGVEPVIKLNEFATENLKPDLTLYYDVEPEISLKRISNNRQNQVDRLDKESMDFYHKVRQAYLSLAESNKERIKVIDASQNLDKVIDDTLSILNNFM
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: HIRA_DROME
Sequence: MRLLKPAWVHHDDKQIFSVDIHKDCTKFATGGQGSDCGRVVIWNLLPVLSDKAEFDADVPKMLCQMDQHLACVNCVRWSQNGQNLASGSDDKLIMIWRKSAGSSGVFGTGGMQKNHESWKCFYTLRGHDGDVLDLAWSPNDVYLASCSIDNTVIIWDAQAFPHSVATLKGHTGLVKGVSWDPLGRFLASQSDDRSIKIWNTMNWSLSHTITEPFEECGGTTHILRLSWSPDGQYLVSAHAMNGGGPTAQIIEREGWKCDKDFVGHRKAVTCVRFHNSILSRQENDGSPSKPLQYCCLAVGSRDRSLSVWMTALQRPMVVIHELFNASILDLTWGPQECLLMACSVDGSIACLKFTEEELGKAISEEEQNAIIRKMYGKNYVNGLGKSAPVLEHPQRLLLPQGDKPTKFPLSNNNEANQRPISKQTETRTKDGKRRITPMFIPLHEDGPTSLSMNIVSSSGSSTTALTSCSAAIGTLPAAAPTESAATPLMPLEPLVSKIDLGRLDSRLKTQPASQRRQSLPFDPGQSNELLRTPRLEEHQSSTCSPSNLNVTATGKSEFVKAALDYRLHVSNGHLKTQHGMLAKVTASDSKEMLWEFYVGSPLVNLNLCEKYAMLCSLDGSMRLISMETGCPVFPAISLTSSAVHCAFSPDNSLVGVLTECGLLRIWDIAKKVVSLAAGCLELLNKHGTAAQFSVTNQGMPLIGFPSGNSYSYSTSLQSWLVLATKDAIMYHGIRGTLPRDMDQMQQKFPLLSMQASSQNYFSFTGSMELRHSESWQQCAKIRFIENQIKLCEALQSLDELQHWHKMLTFQLATHGSEKRMRVFLDDLLSMPEPGISQFVPKLELMQCVLDTLKPHSEWNRLHSEYTELLKECKSERQKDIFATPAPPQQKTASSAGSSPRSGEATGEEVTEKDGATAVAAAVVAGSRMAVTTGTSTTTTTTASSSLSSSGSSSSTSGSGSSSSSSSTSSLSVPQPAPSLSPEIQTLDSPTVCIDDEILSASSSLPPLDTSPVEVSPASTSGGAASTSPAASVAGSAPVSSSKTDQT
What is the function of this protein?
Required for the periodic repression of histone gene transcription during the cell cycle (By similarity).  Required for replication-independent chromatin assembly.  Promotes remodeling of sperm chromatin following fertilization via the incorporation of histone H3. 3 and histone H4.
What are the official names of this protein?
Protein HIRA homolog, Protein sesame, dHIRA.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus. Note=Maternally contributed protein localizes specifically to the male nucleus in fertilized eggs. This localization persists from the initiation of sperm nucleus decondensation to the end of pronucleus formation.
Protein: PHS_RHORT
Sequence: MTDRLDDPALDRQLADHPDWTITSARTALTRSFGFKDFSEAFGFMARVALEAQAQDHHPDWSNSYNRVDITLSTHDSGGLSAKDFALAKAIDRIVG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: VG87_BPMD2
Sequence: MSFHLWMANLDAYMQETFGVGRRDIADWTYHDAYDDGLTFREAAHQAIANELGS
What are the official names of this protein?
Gene 87 protein, Gp87.
Protein: NADK2_BACCR
Sequence: MADRRNLFFFYGDDKATLVEKMKPIYRILEENGFTILDHPKNANAIVSVGDDATFLQAVRKTGFREDCLYAGISTKDEISFYCDFHIDHVDTALQEITKNEIEVRKYPTIQVDVDGSTSFHCLNEFSLRSSIIKTFVVDVHVDDLYFETFRGDGLVVSTPTGSTAYNKSLHGAVVDPLIPCFQVSELASLNNNTYRTLGSPFILNHERTLTLKLRPDGNDYPVIGMDNEALSIKQVEKAVVRLSDKQIKTVKLKNNSFWEKVQRTFL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TJA3_HUMAN
Sequence: GYSSASKIIFGSGTRLSIRP
What is the function of this protein?
J region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha joining 3.
What are the subcellular locations of this protein?
Cell membrane.
Protein: SFH14_ARATH
Sequence: MSGREQTGEKLSDSEYIEEEPRRSRIGNLKKKAFSCSTKLTHPLKMRKGKRKIDFQIPLIEDVRDEKEEKLVSKLRQQLLQKDLLPPVHDDYHMLLRFLKTMEFKIEKTVTAWEEMLKWRKEFGTDRIIQDFNFKELDEVTRHYPQGYHGVDKDGRPIYIERLGKAHPGKLMEVTTIERYLKYHVQEFERTLQEKLPACSVAAKRRVTTTTTILDVEGLGMKNFTPTAANLLATIAKVDCNYYPETLHRMFIVNAGIGFRSFLWPAAQKLLDPMTIAKIQVLEPRSLSKLLEAIDSSQLPEFLGGLCKCPNEGGCLRSNKGPWNDPEIVELVHHMEVNNVPQTTTAPLHVRDYDSTTCTISPKETLKEEPEPEEYYSSTGSRSSMHTCIVPPLSDKASTSDGDKFITTVESIESAQSQLLDADTENTFANTSVREGGQILRFGALREKINSENIFHLVKILLVFPLKLFVLFGFLLPGYWQRQNTVVVPDSSTNNKVLECFDRLKKMEKEFTEISRKQVKIPEANEKLLAESLERIKSLELDLDKTKSVLHITLTKQLQITEQLESQDEERRKGCCF
What is the function of this protein?
Required for transport of secretory proteins from the Golgi complex.  Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes in vitro (By similarity).
What are the official names of this protein?
Phosphatidylinositol/phosphatidylcholine transfer protein SFH14, Protein SEC FOURTEEN HOMOLOGS 14, AtSFH14.
What is the protein family that this protein belongs to?
Belongs to the SFH family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Protein: PSD_CLOB1
Sequence: MIKYYNRKNKDYDIEKVAGEKYLNWTYSSPIGMNLLEVFIKKKFFSKIYGFYCDRRLSHKKINKFINDFKIDMSLSENQSSNFKCFNDFFTRKLKKEARPIKTDKNLLISPGDGKILAYENLNLNSVTEVKGINYSFYELINNDSLAKEYDNGTCLVLRLCPTDYHRFHFIDNGICENTIKLKGFYYSVNPIALSKIPSVFCKNKREYSIFHSENFGDIIFMEVGATCVGSIIQTYKPNTKILKGDEKGYFKFGGSTVILFFKKNTIKIDNDILNQSKLGYETSVVMGESIGIKK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SAT3_ORYSJ
Sequence: MAACVDKWPAAYPCRLPDKFYCALPDCTTTDRPVAPAPAASGSSGDYVWDALRAEAQDDADDEPLLRKFYHDLVLSRPSLESALASLLAAKLCIPGALPQDQLRDLLAGALAAHPEAGRAARADLAAARDRDPACAKMVHCFLYYRGFLALQAHRAAHALWSDNRRAPALLLQSRASEVFGVDIHPGARIGGGILLDHATGVVIGETAVVGYGVSILHAVTLGGTGKESGDRHPKVGDGVLIGAGASVLGNVHIGDGAEIGAGAIVLRDVADGTTAKPIIGKKAEPQRELPGVTMEQRWSD
What are the official names of this protein?
Probable serine acetyltransferase 3, OsSERAT2;1.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: U63B_CONCL
Sequence: KKKRGWDTPAPCHYCQWKGPQCCVYYCSSCNYEEAREEGHYVSSHLLERQGR
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal6.3b.
What are the subcellular locations of this protein?
Secreted.
Protein: DTD_ECOHS
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR10_KARBO
Sequence: PAPESSFIRDP
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-10, FMRFa-10.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECF_STAAB
Sequence: MKLNTLQLENYRNYDEVTLKCHPDVNILIGENAQGKTNLLESIYTLALAKSHRTSNDKELIRFNADYAKIEGELSYRHGTMPLTMFITKKGKQVKVNHLEQSRLTQYIGHLNVVLFAPEDLNIVKGSPQIRRRFIDMELGQISAVYLNDLAQYQRILKQKNNYLKQLQLGQKKDLTMLEVLNQQFAEYAMKVTDKRAHFIQELELLAKPIHAGITNDKEALSLNYLPSLKFDYAQNEAARLEEIMSILSDNMQREKERGISLFGPHRDDISFDVNGMDAQTYGSQGQQRTTALSIKLAEIELMNIEVGEYPILLLDDVLSELDDSRQTHLLSTIQHKVQTFVTTTSVDGIDHEIMNNAKLYRINQGEIIK
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA13_ARATH
Sequence: MSTVGELACSYAVMILEDEGIAITADKIATLVKAAGVTIESYWPMLFAKMAEKRNVTDLIMNVGAGGGGGAPVAAAAPAAGGGAAAAAPAAEEKKKDEPAEESDGDLGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1-3.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: THIG_SALEP
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILAPLIEAGVTLLPNTSGAKTAEEAIFAAQLAREALGTNWLKLEIHPDARWLLPDPIETLKAAEALVKQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETKTMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVMMATAFRLAVEAGLLARQAVPGNRSTYASATSPLTGFLEALA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP1_YEAST
Sequence: MLIEEIEFYNVNGKKTTTVVPENTKIKKRVLNDRRTLYVGNLPKNCRKQDLRDLFEPNYGKITINMLKKKPLKKPLKRFAFIEFQEGVNLKKVKEKMNGKIFMNEKIVIENILTKEEKSFEKNQKSNKKTAPDLKPLSTNTLYVKNIPMKSTNEDLAKIFGVDPKNINFVRRELVDLRTNKVFFSDEFHTGEAFIKFDNLGTGDSIQKKCREFKGRKASNGRVLLVKIASAKKNEQKQEGGDNTKIKQN
What are the official names of this protein?
Ribonucleoprotein 1.
Protein: PYRF_HALSA
Sequence: MSFVEELGARIEAADSVVSVGLDPDMERLPEDVQDAELPRWAFNRRIIDATHEHAAVFKPNAAFYEDSDGWRALRETVAYAHGKGVPVLLDAKRADIGNTARQYAEILAHVDAITVNPYLGEDALQPFLTQDEAGVFVLCRTSNEGGMDFQHLELAAYDRRLYEHVAERAAEWNAQYGDVGLVVGATAPDELQAIRERVPELPFLVPGVGAQGGDAEAAVEYGLNDDGVGLVNSTRGVIFAGEHGSAWAAAAGDAARTLRERLNRHR
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: CAF1A_DANRE
Sequence: MVVVMLAAEEPLASTPRRDMDCVGKANTNKKLVQARLPFKRLNPEPKECNEPKRTKGPVAPKCSEPSDQENDQDSSSISHHGPALVNGRGPLDCFMSRRKRSPLRSAPEATIDLTEDSNDSAKQQPAPPIAATCPLSEEKTKTSEGTTEPTIPLTEEETEKDEAEDVDALPLLDITQDSDTEEEEEEEEEEEEQQQEAEVSHGNESVLSTGSTSSASVIASSPEPSKSAPTTPASTSRINAANKVKRRSLKSVQEQEEKQRQRDEKERLKQEAKAAKEKKKEEARKMKEEKEREKKEKKEKDEKERREKKERDEKEKADKLKAKEEQRQMKIEAKLEEKRKKEEEKRLKEEKDRIKAEKAEITRFLQKPKTQLAPKTLASACGKFAPFEIKAHMSLAPLTRVQCEDSVLEDLDRYLAQPDSTLNGLKDWTGHKPRSSGPTRPRHSAQGDCVVITESQKADDGPDRSRYGRMKLLHFHDNYRPAYWGTWSKKSTHISPRCPLRLDKDLLDYEVDSDEEWEEEEPGESLSHSEGDDDDEAGEDDDDDDGFFVPHGYLSEGEGALEDEEGGDPEKQKVRQRMKAREWENELMSKGKVKVLEAVVRGCFWEGEKPLPDFLQPYAVCMLEPLSKDEASTPEQDASRQQRNEKLLTMLLPLLHGNVNSNKVIITEFLEFCRQQTSSPTESLLNTTESIPPRIHVRRIIKENAVYEKRSTFKRCCWYVHADVLARYSQEALPVPCQWSYLTSGANVTRDEHSGSQGNSPTTNSSTTPSNKRKSASSHSITKYMKKCGESEQTEAMETDGFQADTEDDEDDDCIIIGEQSGSSEQDINTSLPQTDRETEPMDTSASETAALALPCPTPATA
What is the function of this protein?
May be involved in chromatin assembly in DNA replication and DNA repair.
What are the official names of this protein?
Chromatin assembly factor 1 subunit A, CAF-1 subunit A, Chromatin assembly factor I p150 subunit, CAF-I 150 kDa subunit, CAF-I p150.
What is the protein family that this protein belongs to?
Belongs to the CHAF1A family.
What are the subcellular locations of this protein?
Nucleus. Note=DNA replication foci.
Protein: MEIOB_RAT
Sequence: MAKFFALKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPNHFVNVSSWGSEDYIRSLSDNFKVGECVIIENPLIQRKETEREERFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLFDETEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANILLNFIRENKETSIADEIDSYLKESVNLNTIVNVYTVEQLKGKALENEGKVDPFYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNDASNTCTICSKDSSRSRSFCLSFDVLVDLTDHTGTLRSCSLSGSVAEETLGCTINEFLTMTSEQKTKLKWQLLLERSKIYLKLILSHRARGGLKVTILSCKLADPIEASRDLAGQGHT
What is the function of this protein?
Single-stranded DNA-binding protein required for homologous recombination in meiosis I.  Required for double strand breaks (DSBs) repair and crossover formation and promotion of faithful and complete synapsis.  Not required for the initial loading of recombinases but required to maintain a proper number of RAD51 and DMC1 foci after the zygotene stage.  May act by ensuring the stabilization of recombinases, which is required for successful homology search and meiotic recombination.  Displays Single-stranded DNA 3'-5' exonuclease activity in vitro.
What are the official names of this protein?
Meiosis-specific with OB domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the MEIOB family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome. Note=Co-localizes with the RPA complex on meiotic chromosome axes. Accumulates on resected DNA. Localization is dependent on SPATA22.
Protein: UBIK_ECOLI
Sequence: MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRLDLVSREEFDVQTQVLLRTREKLALLEQRISELENRSTEIKKQPDPETLPPTL
What is the function of this protein?
Required for efficient ubiquinone (coenzyme Q) biosynthesis under aerobic conditions (PubMed:28559279, PubMed:30686758).  UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both (PubMed:28559279).  Dispensable for ubiquinone biosynthesis under anaerobiosis (PubMed:28559279).
What are the official names of this protein?
Ubiquinone biosynthesis accessory factor UbiK.
What is the protein family that this protein belongs to?
Belongs to the UbiK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_CHRVO
Sequence: MRFDKLTTKFQQALGDAQSLAVANDNPYIEPQHLLLAMLDDAEAGVGGLLARAGVNVPALKAGLKQAIDRLPRVQGHGGEITVSRDLANLLNIADKIAMKLGDEFIASELYLSALSQDKGEAGRLLKEHGGNHASIQAAIDAVRGGESVNSADAEGQREALKKYTMDLTERARQGKLDPVIGRDDEIRRAIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPESLKNKRLLVLDLAALIAGAKYRGEFEERLKAVLNDLSKDDGQTLIFIDEIHTLVGAGKADGAMDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQKVLVGEPSVEDTIAILRGLQEKYEIHHGVDITDPAIVAAAELSQRYITDRFLPDKAIDLIDEAASRIKMELDSKPEAMDKLDRRLIQLKIEREAVNKESDEASQKRLKLIEDEIAELSREYADLEEIWKAEKAAQQGSQSIKEEIDRLKVDMEELKRKGDWQKLAELQYGKLPQLEARLKEAESAGDKGEAKPNRLLRTQVGAEEIAEVVSRATGIPVSKMLTGEREKLLKMEDVLHQRVVGQDEAVSAVADAIRRSRSGLADPNKPYGSFLFLGPTGVGKTELCKTLASFLFDSKDHLIRIDMSEYMEKHSVARLIGAPPGYVGYEEGGYLTEQVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTVIVMTSNIGSQQIQAMATDDYQVIKLAVMAEVKTQFRPEFINRIDEVVVFHGLDEKHIQSIARIQLKSLENRLAKLELSLQISDEALALLSEAGFDPVYGARPLKRAIQAELENPLAKAILAGKYPPKATVMVEARNGQLAFA
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_LATSS
Sequence: MQKNIIDELTWRDAINQQTDADGLRELTEKKSISLYCGVDPTGDSMHIGHLIPFMMMKRFQLAGHHPYIVIGGGTGSIGDPSGRKSERQLQTMEMVQHNVEALSGQMKRLFGEDANVSMVNNYDWLSKISLLDFLRDYGKLFNINTMLAKDVVASRLDVGISFTEFTYQILQSVDFMHLYKAHDVQLQIGGADQWGNITSGIDMIHKIEGSETEVYGLTIPLMLKADGTKFGKTAGGAIWLDPEKTTPYEFYQFWLNQDDRDVVKYLKYFTFLDEAEINELAKTVETAPEKREAQRRLAEEVTRFVHGQAELEGAQKITEVLFSGDIKALDVKEAEQAFQKAPTVEITAEKKNIVDFLVDAGIESSKRQAREDVQNGAITINGDRLRETTLEIDPSENFEGKFVIVRRGKKKYFLARVK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFCA_ASPOR
Sequence: MRSLVLLGMSSLATANSLWSSKAASWDTTNEAYTLGNGKLGVMPFGEPGAEKLNLNHDELWEGGPFEVNGYRGGNPNSSMTEILSEVRDEIWKKGTGNDSRLHGDTDGYGSFHSLANLTIAIDGIDKVSDYTRSLDLGTGIHTTTYSTGKGKYTTDVYCSYPAQVCIYKLNSTATLSKVTIYFDQLVEESSLWNATCDSDFARLRGVTQEGPPRGMTYDTIARSSIPGRCDSSTGKLAINARNSSSLTIVIGAGTDFDGTKGTAATDYTFKGEDPAEYVEKITSSALSQSESKLRTEHIEDYSGLMSAFTLDLPDTQDSTGTELSTLITNYNANKTDGDPYLEKLLFDYGRHLFISSSRANSLPPNLQGVWSPTKNAAWSGDYHANINLQMNLWGAEATGLGELTVAVFNYMEQNWMPRGAETAELLYGGAGWVTHDEMNIFGHTGSLVVNPCTSPEQGPTTFGCTHWQQLIHQVYENAIQGAEIAGETDSTLLKDIKDQLPRLDKGLHIGTWGQIKEWKLPDSYDYEKEGNEHRHLSHLVGWYPGWSLSSYFNGYNNATIQSAVNTSLISRGVGLYTNAGWEKVWRSACWARLNNTEKAHYELRLTIDQNIGQSGLSLYSGGDTPSGAFQIDANFGYLGAVLSMLVVDMPLDSTHSEDDVRTVVLGPAIPAAWAGGSVKGLRLRGGGSVDFSWDSEGLVDKASATGVSSNVRIVNVEGTVLV
What is the function of this protein?
Alpha-fucosidase involved in degradation of fucosylated xyloglucans.  Hydrolyzes alpha-1,2-linked fucose (By similarity).
What are the official names of this protein?
Probable alpha-fucosidase A, Alpha-L-fucoside fucohydrolase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 95 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMO_THEAB
Sequence: MNFYVDVLGCPKNEADCALLKAYLEKKGNNIVNTIEDADAVVIDTCGFILEAKKESIEEILTYLELKKERDLKVYVTGCLVQRYGEELKKEIPEVDGWFGILPPEKIAENIGKESIIPKNPEPVYEFGGRVDEKQYAYVKISDGCDRACSFCTIPLFKGSFKSRKIDDIVKEVEYLILSGKKEIILVAQDTTGYGIDLYGKQMLPELLKRINDIPGDFWIRVMYMHPDHITDEIIEAFSYDKVLKYFDIPVQHGSDKVLKLMNRTKKSEHILKLVEKIRKRYEDAVLRTSIIVGFPGETDEDFEELLDFIKMVRFERLGAFIYSDEEEAPSYHFEGKVPEIVAQERLDILMEEQSKISFEINEKMVGKTFKVLFDEEEEGVLIARSYMDAPEIDGNIFVPGKFEEGFFKVKVTSADVYDLEGKIVEE
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRY_KLEPN
Sequence: MYKKRKLAILIALLTGTAAAHGQTDLNSIEARLAALEKRLQDAETRASTAESRAASAEQKVQQLTQQQQQTQATTQQVARRTTQLEEKAERPGGFEFHGYARSGVIMNDSAASTKSGAYMTPAGETGGAIGRLGNQADTYVEMNLEHKQTLDNGATTRFKVMVADGQTTYNDWTASSSDLNVRQAFVELGNLPTFEGPFKGSTLWAGKRFDRDNFDIHWIDSDVVFLAGTGGGIYDVKWNDSLRSNFSLYGRNFGDIADSSNSVQNYIVSMNNFAGPVQMMVSGMRAKDNDDRQDANGNLVKGDAANTGVHALLGLHNESFYGLRDGTSKTALLYGHGLGAEVKGIGSDGALRPGANTWRFASYGTTPLSDRWFIAPAVLAQSSKDRYVDGDSYQWATLNLRLIQEVTQNFALAWEGSYQYMDLQPEGYNDRHAVNGSFYKLTFAPTFKVGSIGDFFSRPEIRFYTSWMDWSKKLDNYANDDALGSNGFKSGGEWSFGMQMETWF
What is the function of this protein?
Porin for sucrose uptake.
What are the official names of this protein?
Sucrose porin.
What is the protein family that this protein belongs to?
Belongs to the porin LamB (TC 1.B.3) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.