PharMolix/UniProtQA huggingface dataset:
Protein: MLAF_ECO57
Sequence: MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWILADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS
What is the function of this protein?
Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Intermembrane phospholipid transport system ATP-binding protein MlaF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. MlaF family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DPCKG_METAC
Sequence: MSVHIELPTELRPLMKRPLGTLYRGKGRDTVEKFVGELASPTKLISVGDVTTFHLLEAGIIPDICIVDNRTKRKPVSRDVSDRNRDKVYEEVSVDNPAGIITDELIKTLCEAFDSEKLLRIFVRGEEDLATLPVILMAPLGSVVLYGQPDEGVVFVRVTEEKKEEIRVLFEKLISKNQNTELDKIRRILDGHKDP
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: PRDX1_GEKJA
Sequence: MSSGNAYIGKLAPDFQATAVMPDGQFKEIKLSDYKGKYVVLFFYPLDFTFVCPTEIIAFSDRSEEFRKINCEVIGASVDSHFCHLAWINTPKKQGGLGSMHIPLVSDTKRVIAKDYGILKEDEGISYRGLFIIDDKGTLRQITINDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWQPGSDTIKPDVQKSKEYFSKHK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.  Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (By similarity).  Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
What are the official names of this protein?
Peroxiredoxin-1, Thioredoxin-dependent peroxiredoxin 1.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PREA_BACTU
Sequence: MNKFAIIHMQKFQISDVQGIQKHNQRQGKSKSNLDIDYSKSEQNYDLLNQQKIRYESTIKQEISERVKRKPRANSVVLSEFVVTASPDYMHSLSLEEQKRYFESSLDFIQKRYGKQNTLYAMVHMDEATPHMHIGVMPITEDNRLSAKDMFTRKELISLQQDFPLEMREKGFDVDRGEGSEKKHLSPQAFKEKQDLEVEVEQLSNVKTHLKTKVVETHNQLQQTTNYIEKQNETLQKIQQQFLSLDKKIKEKKQEFETFRNQIPDKPVSMSYLREETKTEVTTKLFGKPEITEKKTGNIVVTREQWRDMTEKVNAAVIVKKDYERLQKTDLVKENQSLREDNKYLEETIKGNNLALKHSYKQNRELEEVNKELHTEIGTLKAHIRDLQMNIKVLYQQTKKVFKEQFKAFRGLIKNELDMKGVDNQFEREHTREIRSRQKGYDMER
What are the official names of this protein?
Plasmid recombination enzyme, GI2 site-specific recombinase, Mobilization protein.
What is the protein family that this protein belongs to?
Belongs to the plasmid mobilization pre family.
Protein: HEM3_STAA1
Sequence: MRKLVVGSRRSKLALTQSQQFINKLKAVEPNLEIEIKEIVTKGDRIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELPFDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTEDYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKVHNDEVAKCVTAERTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTMNGTDPVELGKTVSNKLKEQGAYEIIKRLNEQH
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ABTIR_ACIB9
Sequence: MSLEQKKGADIISKILQIQNSIGKTTSPSTLKTKLSEISRKEQENARIQSKLSDLQKKKIDIDNKLLKEKQNLIKEEILERKKLEVLTKKQQKDEIEHQKKLKREIDAIKASTQYITDVSISSYNNTIPETEPEYDLFISHASEDKEDFVRPLAETLQQLGVNVWYDEFTLKVGDSLRQKIDSGLRNSKYGTVVLSTDFIKKDWTNYELDGLVAREMNGHKMILPIWHKITKNDVLDYSPNLADKVALNTSVNSIEEIAHQLADVILNR
What is the function of this protein?
NAD(+) hydrolase (NADase) that catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide (PubMed:29395922).  In addition to ADPR, also generates a cyclization variant of cyclic ADPR (cADPR), termed 2'cADPR (v-cADPR) (PubMed:29395922, PubMed:36048923).  Cleaves NADP(+), but does not cyclize the product (PubMed:36048923).
What are the official names of this protein?
2' cyclic ADP-D-ribose synthase AbTIR, 2'cADPR synthase AbTIR, NAD(+) hydrolase AbTIR, TIR domain-containing protein in A.baumannii, AbTIR.
Protein: VASAL_PENVA
Sequence: MSDDWDETDAAPASDWNIESFGLPTSFGSTKKTCNTGNAFNDGEGGFDEGSQSNFDDPFRSGGGGFGGRGRGGPRACFKCGDEGHMARDCPSASDSRGNRTNNRRQDNWGGGSSSKPANGEPFGFGSAFGDNQESDPFGATESSGFGFGSGSGSRGGRRNDGGRGCFKCGEEGHMSRDCPSGGGRNKGCFKCGQEGHNARDCPNPGEGSEEKKPRAPLYIPADVNEDELFVMGIEAGSNFDAYANVPANVSGAEPIQPAAESFQSMNLRPLLLENIVKAGYGCPTPVQKYTIPNVMNGRDIMACAQTGSGKTAAFLLPMLHYILDNNCPSNAFEEPAQPTGLVICPTRELAIQIMREARKFSHSSVAKCCVAYGGAAGFHQLKTIHSGCHILVATPGRLLDFLEKGKIVFSSLKYLVLDEADRMLDMGFLSSIKTVINHKTMTPTAERITLMFSATFPHEIQELASAFLNNYLFVVVGTVGAANTDVKQEVLCVPKFEKKAKLVEMCEEILISADDEKILVFVEQKRVADFVGTYLCEKKFRATTMHGDRYQAQREQALSEFRTGVHNILVATAVTARGLDIKGIGVVVNYDLPKDIDEYVHRIGRTGRLGNRGLSISFYDDETDACLTKDLVKVLSEANQTIPDWLTQKANASGHAQTYHGSGLFASSDIRSKNGGGRGWEKNQASSFLGGPSESNVDEEWD
What is the function of this protein?
Involved in translational control mechanisms operating in early stages of oogenesis.  Required maternally in many stages of oogenesis, including cystocyte differentiation, oocyte differentiation, and specification of anterior-posterior polarity in the developing cysts.  Essential for the formation and/or structural integrity of perinuclear nuage particles during germ cell formation.
What are the official names of this protein?
Probable ATP-dependent RNA helicase vasa-like, Vasa homolog, Lv-Vasa, Vasa-like protein.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX4/VASA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Later seen in the pole plasm at the posterior end of the oocyte as a component of polar granules (By similarity). Localized to the cytoplasm of the oocyte throughout oogenesis (PubMed:16955407).
Protein: DPS_HELPY
Sequence: MKTFEILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHHPLVTLSEAIKLTRVKEETKTSFHSKDIFKEILEDYKYLEKEFKELSNTAEKEGDKVTVTYADDQLAKLQKSIWMLQAHLA
What is the function of this protein?
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity).  Required for the survival in the presence of oxidative stress.  Dps is also a virulence factor that activates neutrophils, mast cells and monocytes.  It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin.  It might have a role in the accumulation of neutrophils and monocytes at the site of infection.  Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases.
What are the official names of this protein?
DNA protection during starvation protein, Bacterioferritin, HP-NAP, Neutrophil-activating protein A, NAP A.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB_SULIK
Sequence: MLSVREFSNISMIKGPLIYVQGVTDASYNELVEIEMPNGEKRRGLVIDSQMGIAIVQVFEGTTGVSPTGTKIRMLGRGLEVKISEEMLGRIFNPLGDSLDNGPPVIKGEKRDINGSPLNPAAREYPEEFIQTGISAIDGLNALLRGQKLPIFSGSGLPANMLAAQIAKQATVRGEESNFAVVFAAIGARYDDALFFRKFFEETGAINRVAMIVSLANEPPVMKTLTPKTALTLAEYLAFEQDMHVLAILIDMTNYCEALREISAAREEVPGRGGYPGYMYTDLATIYERAGKVLGKKGSITQMPILTMPNDDITHPIPDLTGYITEGQIVLDRALYNKGIYPPINVLMSLSRLAKDGIGEGKTRDDHKDVSNQLFASYARAVDTRGLAAIIGEDSLSEVDRKYLLFGELFERKFVSQGFNENRDIETTLDIGWEILSVLPESELTNIKTQYIKKYHPNYRGKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: FDM_PSEPU
Sequence: MAGNKSVVYHGTRDLRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPKGHVLGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPDADLGAFGFDLKGWSGGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPTGFHGCVSAGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGFETIDLRNSAPLRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVRAGGAIGIPGIYVGSDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYNRHLTEAILWDQMPYLSKVMNIEVITLDQAPDGYAKFDKGSPAKFVIDPHGMLKNK
What is the function of this protein?
Active against a range of primary alcohols as well as some secondary alcohols.  Exhibits higher activity against alcohols with longer carbon chains.
What are the official names of this protein?
Formaldehyde dismutase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: RECA_STRAM
Sequence: MAGTDREKALDAALAQIERQFGKGAVMRMGDRSKEPIEVIPTGSTALDVALGVGGLPRGRVIEVYGPESSGKTTLTLHAVANAQKAGGQVAFVDAEHALDPEYAQKLGVDIDNLILSQPDNGEQALEIVDMLVRSGALDLIVIDSVAALVPRAEIEGEMGDSHVGLQARLMSQALRKITSALNQSKTTAIFINQLREKIGVMFGSPETTTGGRALKFYASVRLDIRRIETLKDGTDAVGNRTRVKVVKNKVAPPFKQAEFDILYGQGISREGGLIDMGVEHGFVRKAGAWYTYEGDQLGQGKENARNFLKDNPDLANEIEKKIKEKLGVGVRPEEPTATESGPDAATAESAPAVPAPATAKVTKAKAAAAKS
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCAD2_MOUSE
Sequence: MASVSTHGNQEKSPHLPPLSKQSLLFCPKSKLHIHRGEIAKIIRECQEESFWKRALPFSLISMLVTQGLVHQGYLAANPRFGSLPKVALAGLLGFGLGKASYIRVCQSKFHSFEDQLRGAGFGPEHNRHCLLTCEDCKTRRGLSEKAGSQPSAS
What are the official names of this protein?
OCIA domain-containing protein 2.
What are the subcellular locations of this protein?
Endosome.
Protein: UTR2_ARATH
Sequence: MKEEQTRSLFGISLSDKPTWQQFLICTSGFFFGYLVNGVCEEYVYNRLQFSFGWYFTFIQGFVYLFLIYLQGFTTKHIVNPMRTYVKLSAVLMGSHGLTKGSLAYLNYPAQIMFKSTKVLPVMIMGAFIPGLRRKYPVHEYISAFLLVLGLILFTLADAQMSPNFSMIGIMMITGALIMDAFLGNLQEAIFTMNPETTQMEMLFCSTVVGLPFLFVPMVLTGEVFRAWTACAQHPYVYGVLVFEAMATFIGQVSVLSLIALFGAATTALITTARKGVTLLLSYLIFTKPLTEQHGSGLLLIAMGIVLKMVPMDSKAPAKIPARPAVRIAGGDGDREEDEERKSLV
What is the function of this protein?
Sugar transporter involved in the transport of UDP-galactose form the cytoplasm into the Golgi apparatus.
What are the official names of this protein?
UDP-galactose/UDP-glucose transporter 2, AtUTr2.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. UDP-galactose:UMP antiporter (TC 2.A.7.11) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: AROA_SULSY
Sequence: MEKTVKKVKRIEGSLRVPSDKSISHRAIILSSLADGTSIVKNFLKAGDTLTTVNAYRKLGVEIVEKEGVYYVHGKGLDGLKEPDDLLDMGNSGTTTRLTLGVLAGFDFFAALTGDDSLRKRPMKRVAEPLSKMGAKIDGRKDGNLLPISIRGGKLTGIDFFNEKMSAQVKSAILLAGLFAKGDTTVIEPVISRDHTENMLNSMGAYVSREFTKDGYRVTVKKADKLNPIHINVPADPSSAAFFAAAASIISGSHIELKDVLINPTRDGFFRKLKEMGAKVEYKNKRDEAGEIVADIYISYHELKGVKVEPQEVPSMIDEIPLLAIIATQAEGETVITGAHELRVKESDRIKSVIENFKRLGLEAEELPDGMIIRGKQKVKGGIVDSYKDHRIAMGFAILGLVSEEGITIKDADCVYISYPEFFNHLEKVSK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNB_SYNY3
Sequence: MKKVEAIIRPFKLDEVKIALVNAGIVGMTVSEVRGFGRQKGQTERYRGSEYTVEFLQKLKIEIVVDEGQVDMVVDKLVSAARTGEIGDGKIFISPVDSVVRIRTGEKDTEAI
What is the function of this protein?
P-II indirectly controls the transcription of the GS gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is phosphorylated, these events are reversed.  In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is phosphorylated which allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II, PII signal transducing protein.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: RSMH_WOLSU
Sequence: MESPHLSVLKNEVLEIFAPLSEGYFIDCTLGFGGHSEAILKAHPKLSLIGIDQDPHALEFSQKRLAPFKDRFSFREGRFSEVLPTLKELPIAGILADIGVSSLQLDDSSRGFSFHSERLDMRMNPNAQLSALEVVNSYPQDRLERIFKEYGEIKESKKLVSLISEERKKGRITSAEALSRLIERHFKRVGNIHPATLAFQAIRIEVNDELGEIGRALQTIGEIAKGRVSIISFHSLEDRLVKNFFKEWSNSCLCPPEAFRCTCGNNHEKGQILTKKPLVATPEESKANPRSRSAKMRAFEFKS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_LYSSC
Sequence: MRVPVATKSHHYEVLLGHRFLTEAIQTYADQLNKADKFFVFTDAHVWEAQGDYFKANFPYDFEVFILPGGEACKTFEQYYAAQTFLLEQKCSRKSFVFAFGGGAVGDLTGFVAATYMRGIPFIQIPTTILAHDSAVGGKTAINHPLGKNMIGAFYQPEGVIYDTVFSETLPVREIRSGTAELIKHAMISDSAWLEELMAADSVMHFNQQELAMQLKKGIEVKAKIVAEDETEQSVRKFLNLGHTYGHAIEAAAGYGKVAHGEAVMIGLVYCLLLSERYGELNRPFTKAFLQFAVKNGYPFEAVNDYTFEQLTSYLMKDKKTEYGILQFVLLEKIGKPFVRAIDLKECKEVDAEYRELLAEVLV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNP_BOVIN
Sequence: MADGKAGEEKPEKPQRAGAAGGPEEEAEKPVKTKTVSSSNGGENSSRSAEKRSAEDETADLPTKPTKISKFGFAIGSQTTKKASAISIKLGSSKPKEPVPTLAPKTLSVAAAFNEDEDSEPEEMPPEAKMRMKNIGRDTPTSAGPNSFNKGKHGFSDNQKLWERNIKSHLGNVHDQDN
What is the function of this protein?
May be involved in cell cycle regulation.
What are the official names of this protein?
PEST proteolytic signal-containing nuclear protein, PCNP, PEST-containing nuclear protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: DMGD_HALED
Sequence: MKIERAYTIVTAPGRNFVTLKIVTDEGTYGIGDATLNGREMAVVAYLEEHVIPALIGRDPQRIEDIWHYLYRGAYWRRGPVTMSAIGAVDMALWDIKAKVAGMPLYQLLGGKSRERVMVYGHATGKDIEACLDEVARHVEEGYRAVRVQAGVPGIASIYGVAKKPGERYEPADAELPAEHVWNTAKYLNHAPKLFAAVRERFGDDLHVLHDVHHRLTPIEAARLGKEVEPFNLFWLEDCVPAENQESFGLIRQHTTTPLAVGEVFNSLYDAKALIENQWIDYIRAPLTHAGGITHVRRLADLAGLYHVRTGFHGPTDLSPVCLGAAIHFDTWVPNFGIQEYMPHEAVTDEVFPHDYRFEDGHFLVGETPGHGVDIDEEKARKYPYRRASLPVNRLEDGTLWHW
What is the function of this protein?
Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds.  Has no detectable activity with a panel of 70 other acid sugars (in vitro).
What are the official names of this protein?
D-galactonate dehydratase family member RspA, D-gluconate dehydratase, D-mannonate dehydratase, Starvation sensing protein RspA homolog.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: ENO_SACS2
Sequence: MINRFSIEKVKGLEIVDSRGNPTIRVFIRTSDGVESFGDAPAGASKGTREAVEVRDENGLTVKRAVDIVNYIIDPALHGIDVREQGIIDKLLKDIDSTENKSKLGGNTIIATSIAALKTASKALGLEVFKYISGPRLPKIPIPLLNIINGGLHAGNKLKIQEFIIVPIKFNTFKEALFAAIDVYRTLKGLITERYGKIYTAVGDEGGFSPPLEDTREALDLIYTSINNAGYEGKIYMGMDAAGSDFYDSKKEKYIIDGRELDPNQLLEFYLDLVKQYPIVYLEDPFEENSFDMFSQLQNKLSSTIITGDDLYTTNIKYLKIGIEKRSTKGVIVKPNQVGTISETFEFTNLARRNSMKLITSHRSGETEDNFIADFAVGIESDFIKVGAPARGERTSKYNKLLEIENKFGLEYEGKYFYL
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GLCAE_SULTO
Sequence: MNNPYENWINFFQEALNTNIPSIEKIEELVYLGIGGSGIPGRILEILELPVKYQLFRGYKVKVNEKSTVIAVSYSGNTTETIFALLTSLKKTRKAIVITSGGKIEEIASKHNLPVIKLPKGLQTRFVFPYIFTYLIRIINEGLGTNYNVNELVEGIKDYSKLNEISGILASQIIGKIPIIYSSTFLPIAERFKQEINENAKYPAFYNELPEANHNEIELYSYPSPYTFYPIVIVSDKLDEESANLINAYKIYPLYQSILKNIASLTLLAGLTSVKLAMLLGVKPEQLNIIPKIREKTFKLFEGDINADQNL
What is the function of this protein?
Involved in the synthesis of UDP-N-acetylgalactosamine (UDP-GalNAc).  Catalyzes the conversion of glucosamine-6-phosphate (GlcN-6-P) to galactosamine-6-phosphate (GalN-6-P).
What are the official names of this protein?
D-glucosamine-6-phosphate 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the PGI/PMI family.
Protein: LEUC_BORPA
Sequence: MAQTLYDKLWDAHVVHQESDGTCLLYIDRHLLHEVTSPQAFEGLALAGRQPWRVGANLAVADHNVPTLNRAQGIEDPISRLQVDTLDDNCAKYGITEFRMNDLRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGALGALAFGIGTSEVEHVLATQTLLMKKAKSMQINVEGELPFGCTAKDVVLHIIGIIGTAGGTGHAIEFSGSTIRGLSVEGRMTVCNMAIEAGARSGMVAVDDKTIDYFRGRPFAPVGVLWDQAVGYWRTLHSDAGARFDRVINVDARDIKPQVTWGTSPEMVLPVDGRVPDPDREKDDVRRSGMERALEYMGLKPNTPLVDIRVDRVFIGSCTNSRIEDLRAAAVVARGKRVAANVRQAMVVPGSGLVKQQAEREGLDKIFIEAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGQGGRTHLVSPAMAAAAAVAGHFVDVRSFR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: AROC_PELPB
Sequence: MIRYFTAGESHGPALSAIVEGMPAGITITPKEINTQLARRQQGHGRGGRMKIESDKAEILSGVRFGKTIGSPITLVINNRDWQNWTTTMAQFEKPDEQCSKITIPRPGHADLAGRIKYGFDDIRPVIERSSARETAARVAAGTVARLFLKALGIEIGSYISAIGSAAEASPDKQLEGLLLEGAEAVARQADLSPVRMLGKETETNALAAIDGASERGDTLGGIIEIFITGVPPGFGSYVQHDRRLDAALAAAIISIQAIKGVEIGTAFENARKPGSEVHDEFHLSREKGVIRKTNRAGGLEGSMSSGQTIHLRAAMKPISSLVTPLLSFDVETLQATPSRFERSDTCAVPAAGVVAEAVLAPVIANALLEKLGGDHLDEIRQRLDLYRESIRSTFHS
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: FITM2_XENLA
Sequence: MERLENCAQMFQRKFLNEAFRRHCPVLLACIALGGSLLKELSPLPDSYWNNKRNVLNVYFVKFCWGWTLWLLLPFITLTNYKLTGSITKVLRRLSSLLVGTLFWYLCTNLFLYIEHITGSCYESEALLDSIEHQDRKECRLHGGFWHGFDISGHCFLLSYCILIILEETSVIRSIQFERHWHRMAINAQFTALSILVIIWVWMFLCTAVYFHNIFQKVIGTAFGMLAWYITYRWWYLQPISPGLPPASASHSEKEPVYKN
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (By similarity).  Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen (By similarity).  This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis (By similarity).  May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis (By similarity).  May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation (By similarity).  May play a role in the regulation of cell morphology, ER morphology and cytoskeletal organization (By similarity).
What are the official names of this protein?
Acyl-coenzyme A diphosphatase FITM2, Fat storage-inducing transmembrane protein 2, Fat-inducing protein 2.
What is the protein family that this protein belongs to?
Belongs to the FIT family. FIT2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CLEA_CONBY
Sequence: MKLSVMFIVALVLSLSMTDGLPRRAENGGRIFRQHSPDSMDPQTRQIKTRTLCPEHCTNGCNMDMTCI
What are the official names of this protein?
Conotoxin ba14a, Conotoxin ba14.1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin L superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL28_NEIM0
Sequence: MARVCKVTGKRPMSGNNVSHANNKTKRRFLPNLQSRRFWVESENRWVRLRVSNAALRTIDKVGIDVVLADLRARGEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.