PharMolix/UniProtQA huggingface dataset:
Protein: PIMT_STRMK
Sequence: MSPRLRLQPEAVGIGMTSQRVRDRLVDRLREAGIVDESTLNAIRVVPRHLFIDEALASRAYEDTALPIGHGQTISQPWVVARMTEAVLQVSPKKVLEVGTGSGYQAAVLGALGLEIYTVERIGDLLRQARKRFRALGMNIRTKHDDGRAGWAEHGPFDAIVVTAAAPALVDELVGQLAEGGRLVAPVGGPGGQSLVQLDRRADGSIEQRVLAPVTFVPLLSGMLD
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARF5_CHICK
Sequence: MGLTVSAIFSRIFGKKQMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNICFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVQESAEELQKMLQEDELRDAVLLVFANKQDMPNAMVVSELTDKLGLQALRSRTWYVQATCATQGTGLYDGLDWLSHELSKR
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 5.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: KDSB_SHEON
Sequence: MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDERIKSAVEGFGGKVVMTSPDAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGYEIVNKAELDDPMHVKMVFDNDYYALYFSRARIPFGRDTKDYPVYKHLGVYAYTRRFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKVAISAFDSIEVDTPEDIRKCEQRLAVD
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_VIBCM
Sequence: MATVSTNEFKGGLKIMLDNEPCVILENEYVKPGKGQAFNRVRIRKLLTGKVLEKTFKSGDTAEVADVVDIDLDYLYNDGEFYHFMNNSTFEQLAADAKAVGENAKWLVENNTCMLTLWNGNPIAVTPPNFVELEVTETDPGVKGDTQGTGGKPATLSTGAVVRVPLFVQIGEVIKVDTRSAEYVGRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUXX_PYRHO
Sequence: MAERPLDVIHRSLDKDVLVILKKGFEFRGRLIGYDIHLNVVLADAEMVQDGEVVKKYGKIVIRGDNVLAISPTEE
What are the official names of this protein?
Putative snRNP Sm-like protein.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: ACDA3_METAC
Sequence: MSKLTTGSFSIEDLESVQITINNIVGAAKEAAEEKAKELGPMGPTAMAGLASYRSWNLLLLDRYEPVLTPMCDQCCYCTYGPCDLSGNKRGACGIDMAGQTGREFFLRVITGTACHAAHGRHLLDHVIEVFGEDLPLNLGESNVLTPNVTICTGLSPKTLGECRAPMEYVEEQLTQLLATIHAGQESAEIDYDSKALFSGSLDHVGMEVSDIAQVSAYDFPKADPEAPLIEIGMGSIDKSKPLIVAIGHNVAGVTYIMDYMEENNLTDKMEIAGLCCTAFDMTRYKEADRRAPYAKIVGSLAKELKVIRSGMPDVIVVDEQCVRGDVLSESMKLKIPVIASNEKIMMGLPDRTDADVDSIVEEIKSGAIPGCVMLDYDKLGELIPKIAEVMAPIRDAEGITAIPTDEEFKVYIDKCVKCGECMLACPEELDIPEALEYAAKGSYEYLEALHDVCIGCRRCEQVCKKEIPILNVLEKAAQKSISEEKGWVRSGRGQASDAEIRAEGLNLVMGTTPGIIAIIGCPNYPAGTKDVYNIAEEFLKRNYLVVVSGCSAMDIGMYKDDDGKTLYERYPGTFSGGGLLNTGSCVSNAHITGAAEKVAGIFAQRTLAGNLAEVADYTLNRVGACGLAWGAYSQKAASIGTGCNIYGIPAVLGPHSSKYRRALIAKTYEEDKWKVFDARDGSEMNIPPAPEFLLTTAETWQEALPMMAKACIRPSDNNMGRSIKLTHWMELSKKYLGVEPEDWWKFVRNEADLPLAKREELLKRLEAEQGWEIDWKRKKIISGPKIKFDVSAQPTNLKRLCKEA
What is the function of this protein?
Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit alpha 3, ACDS complex subunit alpha 3, ACDS complex carbon monoxide dehydrogenase subunit alpha 3, ACDS CODH subunit alpha 3.
What is the protein family that this protein belongs to?
Belongs to the Ni-containing carbon monoxide dehydrogenase family.
Protein: HPRT_METM6
Sequence: MSRLLEESLKTCPIVKRGEYHYFIHPISDGVPLVEPELLRDVSTRVIKMIDTEVDKIVTAEAMGIPIVTAVSIATDIPYVIMRKREYLLEGEIPVHQETGYSKGELYLNGINKGDKVVILDDVISTGGTLVAIINALKRAGADIKDVLCIIDRGNGQNVVEEKTGYKVKTLVKIEVVDGKVQILE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLU_DANRE
Sequence: MVSKTDDIPASVPNCSPADFARDGETANSKGTTSKKEASCACGHGVETAVMNGDAGHDQAEEADSKQDGSGDADQAEDANEQEVIVIQDTGFTVKIQAPGTEPFDLQVSPQEMVQEIHQVLMDREDTCHRTCFSLQLDGNVLDNFAELKSIEGLQEGSLLKVVEEPYTVREARIHVRHIRDLLKSLDPSDAYNGVDCNSLSFLSVFSEGDLGDTGKRKKKGSELEQIDCTPPEHILPGSKERPLVPLQPQNKDWKPMQCLKVLTMSSWNPPPGNRKMHGDLMYLYIVTVEDRHVSITASTRGFYLNQSTTYNFSPKPANPSFLSHSLVELLSQISAAFKKNFTTLQKKRVQRHPFERIATPFQVYSWTAPQIDHAMDCVRAEDAYTSRLGYEEHIPGQTRDWNEELQTTRELSRKNLPERLLRERAIFKVHSDFAAAATRGAMAVIDGNVMAINPGEETRMQMFIWNNIFFSLGFDVRDHYRELGGDSAAHAAPTNDLNGVRAYSAVDVEGLYTLGTVVVDYRGYRVTAQSIIPGILEREQEQSVIYGSIDFGKTVVSHPKYLELLEKTSRPLKVQRHAVLNEKDSAVELCSSVECKGIIGNDGRHYILDLLRTFPPDLNFLPVEGEELTPESQKLGFPRQHRHRLACLRQELIEAFVEHRYLLFMKMAALQLMQQKANKDKTAALQDSNAAGAGSENKPLALESCDGTPDSPTSSESTLTPEDSEATTVSENSSAENQEAMTEVPVASINGTHEPLAAERQNGGCDGPLEGKEADENIPGLAQAKELAESLAAEDGSGIDPKSREVVLNACKAVGSISNTSFDIRFNPDIFSPGVRFPDDSNDDIKKQKQLLKDAAAFLVSCQIPSLVKDCLDHSSLPMDGATLTEALHQRGINVRYLGTVLEFMDNMPAKAQLEHIYRIGISELITRCAKHIFKTYLQGVDLSALSAAVSYFLNCLLSSFPDAVAHLPADELVSRKKSRKRRNRVPGGGDNTAWASLTPSELWKNITSEAHGYYNFSLQCESVDQAVEKYGLQKITLLREISIKTGIQILIKEYNFDSRHKPAFTEEDILNIFPVVKHVNPKASDAFHFFQSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVEICACLRLLARLNYIMGDHPEALSNQQKAVLMSERVLGIEHPNTIQEYMHLALYCFANGQLSTALKLLYRARYLMLVVCGEDHPEMALLDSNIGLVLHGVMEYDLSLRFLENALAINTKYHGPRSLKVALSHHLVARVYESKAEFRSALQHEKEGYTIYKNQVGEAHEKTKESSEYLKYLTQQAVALQRTMNEIYKNGSNASIMPLKFTAPSMASVLEQLNIINGIIFIPLSQKDLENLKAEVQRRQLMQDSGKIQEQQGSHLELDDKLPVDD
What is the function of this protein?
mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria.
What are the official names of this protein?
Clustered mitochondria protein homolog.
What is the protein family that this protein belongs to?
Belongs to the CLU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MT_LYTPI
Sequence: MPGPDVKCFCCRDGKECACGGGECCITGKCCKEGDRTCCGKCSNAACKCADGCKCEGACACTMGNCTC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT, LpMT1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 4 family.
Protein: SYI_DEIRA
Sequence: MTKRTFAPVPTQPNFRQLEADILQKWKDEQVFEQTQTRPAPAGEFVFYEGPPTANGKPALHHVLARSFKDLFPRFKVMQGHHVTRKGGWDTHGLPVEISVEKKLGWLGRNHGASREELEEFNRLCRTSVWETIQDWNELTERMGYWLDLGDPYITYQNSYVESVWNLLRRLHEKGLVAQDYKVVPLSPRISSTLSRAELGEVDSYRMVDDPSVYVRLPIVWDTLPERAHAALSSLSGEQRQGLSLLVWTTTPWTLPSNTLAAVNPDLDYVVADSPSGRVIVAEGAVERLSALHKDAAPLEVLARFKGRDLEWVEYEPPFPEVASQLGVVSELHERRDGKPVLHFVVMADFVSDVDGSGVAHEAPAYGAEDLEVARAYGVPLMFGVDDHGILQVTHEQGKFFKDADKGLIADMKARGLMFWAGTLKHRYPFHDRTGDPILYFAKKGWYIRTSQVAGEMLAQNEKINWVPGNIKHGRFGNWLEGNVDWAISRERYWGTPLPFWQSESGQLRVIGSVAELSELAGRDLSDLDLHRPYIDDITFTLDGEEYRRVPEVLDVWFDSGSMPYAQWGLLLNEQGEAVRGAEQFAKHYPADYICEAIDQTRGWFYSLHAISTMLYDQPAYKNVICLGHIVDEKGLKMSKSKGNVVAPLPLFDQYGADSVRWYMFMASDPGDQKRFSERLVAEAQRSYVNTLWNVYSFFVLYANLDQPDLAAAPAVAERPEMDRWLLARLEETVRDVTAALESYDARSGGRALEGFVDDLSNWYVRRSRSRFWGEGGTVDTAAYATLHEALLVVSQLTAPFTPFLADALYRNLSGEESSVHLTPWPTVRAERLDRKLTADMAAVMKVVELGRAVRGAHNLKTRQPLAGVQVRAASPEALDALKRSQTQIMEELNVKAVTFLEGDTDLVQYSLRPNLPVVGKQYGKQLPVLKKALTEADARAVATAVQAGQGFSVQADGVTFDLTPGSVLVDAKAPEGVAAAEDAGYLVAFDTALTPELVREGLARDLVRAIQEARKAAGFEVQDRIALALELDGEALEAAQAWQDFIAGEVLAEQVAYGSGEGFRAEVEGGAVTLKKL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5DNU_KLEP3
Sequence: MSQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGQVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQKLVDMVPDELRDIFEPLIDEHHYSEEEQSIVKQADALCAYLKCLEELSAGNNEFLLAKGRLEKTLASRRSAEMDYFMQVFVPSFQLSLDEISQDSPL
What is the function of this protein?
Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
What are the official names of this protein?
5'-deoxynucleotidase KPK_1466, 5'-deoxyribonucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the 5DNU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGUA_PSE14
Sequence: MTTLNSTPRADGFHMPAEWAPQTQVWMVWPERPDNWRLGGKPAQAAHVAIAKAIARFEPVTVAVSAAQYDNARARLDVPNIRVVEMSSNDAWVRDSGPTFVINERGEVRGVNWEFNAWGGFDGGLYAPWNLDSQLGSKVLEIERCPRYVTKGFVLEGGSIHVDGEGTLITTEECLLNRNRNPHLTREQIEAILGDYLAVDKVVWLPDGLFNDETDGHVDNFCCYIRPGEVLLAWTDDPEDPNYSRCHAALGILENTLDAKGRAFIVHKMPIPGPLFATEEECAGVDQVHGSQERNPSVRLAGSYVNFLIVNGGIIAPSFDDPMDEKARELLQTLFPEHEVVMAPGRELLLGGGNIHCLTQQQPAPHKA
What is the function of this protein?
Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine.
What are the official names of this protein?
Agmatine deiminase, Agmatine iminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the agmatine deiminase family.
Protein: STOX1_HUMAN
Sequence: MARPVQLAPGSLALVLCRLEAQKAAGAAEEPGGRAVFRAFRRANARCFWNARLARAASRLAFQGWLRRGVLLVRAPPACLQVLRDAWRRRALRPPRGFRIRAVGDVFPVQMNPITQSQFVPLGEVLCCAISDMNTAQIVVTQESLLERLMKHYPGIAIPSEDILYTTLGTLIKERKIYHTGEGYFIVTPQTYFITNTTTQENKRMLPSDESRLMPASMTYLVSMESCAESAQENAAPISHCQSCQCFRDMHTQDVQEAPVAAEVTRKSHRGLGESVSWVQNGAVSVSAEHHICESTKPLPYTRDKEKGKKFGFSLLWRSLSRKEKPKTEHSSFSAQFPPEEWPVRDEDDLDNIPRDVEHEIIKRINPILTVDNLIKHTVLMQKYEEQKKYNSQGTSTDMLTIGHKYPSKEGVKKRQGLSAKPQGQGHSRRDRHKARNQGSEFQPGSIRLEKHPKLPATQPIPRIKSPNEMVGQKPLGEITTVLGSHLIYKKRISNPFQGLSHRGSTISKGHKIQKTSDLKPSQTGPKEKPFQKPRSLDSSRIFDGKAKEPYAEQPNDKMEAESIYINDPTVKPINDDFRGHLFSHPQQSMLQNDGKCCPFMESMLRYEVYGGENEVIPEVLRKSHSHFDKLGETKQTPHSLPSRGASFSDRTPSACRLVDNTIHQFQNLGLLDYPVGVNPLRQAARQDKDSEELLRKGFVQDAETTSLENEQLSNDDQALYQNEVEDDDGACSSLYLEEDDISENDDLRQMLPGHSQYSFTGGSQGNHLGKQKVIERSLTEYNSTMERVESQVLKRNECYKPTGLHATPGESQEPNLSAESCGLNSGAQFGFNYEEEPSVAKCVQASAPADERIFDYYSARKASFEAEVIQDTIGDTGKKPASWSQSPQNQEMRKHFPQKFQLFNTSHMPVLAQDVQYEHSHLEGTENHSMAGDSGIDSPRTQSLGSNNSVILDGLKRRQNFLQNVEGTKSSQPLTSNSLLPLTPVINV
What is the function of this protein?
Involved in cell cycle regulation by binding to the CCNB1 promoter, up-regulating its expression and promoting mitotic entry (PubMed:22253775).  Induces phosphorylation of MAPT/tau (PubMed:22995177).
What are the official names of this protein?
Storkhead-box protein 1, Winged-helix domain-containing protein.
What are the subcellular locations of this protein?
[Isoform A]: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=In epithelial cells, diffusely expressed in the cytoplasm, particularly in peri-membrane cortical regions (By similarity). Concentrated at centrosomes during metaphase (PubMed:22253775). SUBCELLULAR LOCATION: [Isoform B]: Nucleus. SUBCELLULAR LOCATION: [Isoform C]: Nucleus, nucleolus.
Protein: ACEA_MYCLE
Sequence: MAIMDTNTEVHTLFTQEVAATQQYFDDPRFAGIIRLYTARQVVEQRGTIPTDYTVARDAATAFYARLRELFAAGKSVTTFGPYSPGQAVSLKRMGIEAIYLGGWATSAKGSITEDPGPDLASYPLSQVPDDAAVLVRALLAADRNQQYLRLHMTEQQRAATPAYDYRPFIIADADTGHGGDSHVRNLIRRFVEIGVPGYHIEDQRPGTKKCGHQGGKVLVPSDEQIKRLNAARFQLDIMRVPGIIVARTDAEAANLIDSRADERDQPFLLGATNLKIPSYKACFLALVRCFYELGVKELHGHLLYALGDGEYAAASAWLDRQGILAQVSGTVNAWQENGKQSIDDLFEQVEYRLLAAWEKDAGLMTYGEAVEEMLQFGESEGELIGMSPEEWRRFVGRASLYAAREKAKELGVDPGWDCELAKTPEGYYQIRGGIQYAIAKSLAAAPFADILWMETKTADLADARQFAEAIHAEFPEQMLAYNLSPSFNWDTTGMSDEEMKRFPEELGKMGFVFNFITYGGHQIDGVAAEEFATALRQDGMLALARLQRKMRLVESPYRTPQTLVGGPVAMQRWLRPPDVRRQPRPWAKVRPSTSILCRPRCRRSC
What is the function of this protein?
Involved in the persistence and virulence of Mycobacterium.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: XKR9_HUMAN
Sequence: MKYTKQNFMMSVLGIIIYVTDLIVDIWVSVRFFHEGQYVFSALALSFMLFGTLVAQCFSYSWFKADLKKAGQESQHCFLLLHCLQGGVFTRYWFALKRGYHAAFKYDSNTSNFVEEQIDLHKEVIDRVTDLSMLRLFETYLEGCPQLILQLYILLEHGQANFSQYAAIMVSCCAISWSTVDYQVALRKSLPDKKLLNGLCPKITYLFYKLFTLLSWMLSVVLLLFLNVKIALFLLLFLWLLGIIWAFKNNTQFCTCISMEFLYRIVVGFILIFTFFNIKGQNTKCPMSCYYIVRVLGTLGILTVFWVCPLTIFNPDYFIPISITIVLTLLLGILFLIVYYGSFHPNRSAETKCDEIDGKPVLRECRMRYFLME
What is the function of this protein?
Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface (PubMed:25231987).  Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment (PubMed:25231987).
What are the official names of this protein?
XK-related protein 9, hXKR9.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCD_ACTP2
Sequence: MRLCDTDIERYLDEGIIEIIPRPSNEKITGATVDVRLGNSFRVFREHATPYIDLSGPREEVTAQLHKVMSEEIIIADGEAFFLHPGELALATTLESVTLPDNVVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFFNAGKLPLALRPNMAIGALSFEILSGHAAKPYNARKDAKYKNQQSAVSSRINQDD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: NCKP1_ORYSJ
Sequence: MAHVSFKSKEADSMSRWSKYLSTEESPPSASLSWRAMGVDGPQGSASGQKHLQMEPVVQLSKVAEGLLAKMYRLNSILDYPDPNAHTFSEAFWKAGVMPNFPKICITLSKKFPEHPNKLQLEKVDKFALDALNENAEGYMQNLEQWITLLLDLLEFREQALRLILDLSSTVITLLPHQNSLILHAFMDLFCSFVRVNLFSDKIPRKMILQVYNILHIMLKGGRDCEFYHRLVQFVDLYDPPVKGLHEDLNFVSPRIGEVLEAVGPIIFLSTDTKKLRNEGFLSPFHPRYPDILTNSAHPMRAQDLANVTSYREWVLLGYLVCPDELLRVTSIDVAMVVLKENLVLSLFRDEYILLHENYQLYVLPKVLESKRMAKSGRTKQKEADLEYNVAKQVEKMLMEVHEQALVSADALHHERRILLKQEIGRMVLFFTDQPSLLAPNIQMVFSALALAQCEVVWYFQHVGIASSKSSRGRTVDIDAADPTIGFLLDGMGKLCCLVRKYIAAIKGYALSYLSSCAGRIRFLLGTPGMVALDLDATLKGLFQQVLHCLENIPKPQGENVPAITCDLTDLRKHWLSILMIVTSSRSSVNIRHLEKATVSTGKEGLVSEGNAAYNWSRCVDELEGQLSKHGSLKKLYFYHQHLTTVFRNTMFGPEGRPQHCCAWLGAACCFPECASSIIPEEVNKIGRDSISYVESLIESIMGGLEGLINILDSEGGFGSLEMQLSPEQAAIRLNNATRAKAVSGLLAPGHESYPDNSSSVKMLEAAMQRLTSLCSVLNDMEPICVLNHVFILREYMRDCIIGNFRRRFHSMIRTDSCLQRPSVIESLLRRHLSIIHLAEQHISMDLTEGIREVLLAESFTGPFPNLQVFETPTETHGGGSAIDIISNWYIDNFVKDASRTGVVFDASQNCFRSSQPIGGGYLAEAFTDKRELKALVRLFGGYGVDRLDKLLREHTSALLNCIDSALRSNRDALEGLAGSVNSGDRIERDANLKQIIDIETLADFCIQAGQAITFRRLLVEAVGAVLEEKVPLIYSLLKGLAMQLPEEVPDKNEIIRLRRVASSVGVGDKHDAEWVHSILAEIGSANDNSWTLLPYLCAAFMASNMWSTTAYDVNTGGFSNNLHCLARCVSAVVGGSEYTRMEREHRRSSLSNGHMDELQEPELLSRVSAEANIKSAMQLYVKLSAGLVLDSWNDTSRPYIVPKLIFLDQLCEMSPYLPRSTLEVHIPYTILRSIYHQLYGASLMATEPMEPSPRQSPLISLAHASPSMKQNRADTTPRSHTFEPGYHSSSGSQYDEGYEGDRRTGERQLRSMRRSGPLDYTGTRKVKFVEGSSSGSHGAGSGSLQRFAVSRSGPLSYK
What is the function of this protein?
Involved in regulation of actin and microtubule organization.  Part of a WAVE complex that activates the Arp2/3 complex (By similarity).
What are the official names of this protein?
Probable protein NAP1, NAP of plants, Nck-associated protein 1, P125Nap1.
What is the protein family that this protein belongs to?
Belongs to the HEM-1/HEM-2 family.
Protein: S61A1_RAT
Sequence: MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGMEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLIATIFVFAVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSARFSGNLLVSLLGTWSDTSSGGPARAYPVGGLCYYLSPPESFGSVLEDPVHAVVYIVFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGALSVLADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEVGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.  May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins.  The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex.  The SEC61 channel cooperates with the translocating protein TRAM1 to import nascent proteins into the ER.  Controls the passive efflux of calcium ions from the ER lumen to the cytosol through SEC61 channel, contributing to the maintenance of cellular calcium homeostasis (By similarity).  Plays a critical role in nephrogenesis, specifically at pronephros stage (By similarity).
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha isoform 1, Sec61 alpha-1.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes exclusively in granular structures in the endoplasmic reticulum (ER).
Protein: MZRA_CITRI
Sequence: MRKPRVTLRHLAWSTMLLMVLGTGMLFWSAVRQQESTLAIRSIHQGASMPDGFSIWHHLDAHGIRFKSITPENDTLLITFDSSAQSAAAKAVLDKTLPRGYIIAQRENASQAVQWLSRLRDAPHRMG
What is the function of this protein?
Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
What are the official names of this protein?
Modulator protein MzrA.
What is the protein family that this protein belongs to?
Belongs to the MzrA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RECA_MYCMY
Sequence: MSTELQNTIENNDIRESQMWNSKELKEAIKEIEKMFGKGSIMVLGQSDNLNIETFSSGSLLLDNALGIGGYPKGRIIEIYGPESSGKTTLSLHAICEVQKLGGIAAFIDAEHSLEPKYCQTLGIDTNKLLVSQPDNGEQALDILEMLINSNSIDLIVVDSVAALVPKTELDGEMSDQSIGLQARMMSKALRKLNWLIAKSNTTVIFINQLREKIGVIFGNPETTTGGKALKFFSSIRLEVRKAENILNNYEIIGNKIKIKVVKNKTAIPFKTTTISLLYNKGIDKLGELVDLLVSYEIIEKSGVWYSYQNEKIGQGRTSVIQWLNADENRINELTEQVKKLIKQD
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_LEUMM
Sequence: MIIGIGNDTEAISRVAEIVERQKSFITLILTPAERAAAAERKGKHQNEYIAGRFSAKEAFSKATGYGIGEKVQWQDIEILNEPNGRPVMKVKNFPYHTYVAITHSGDQVNTVVVIERLTLLEKMSIKLFPKRGVLS
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMXL1_HUMAN
Sequence: MVEADRPGKLFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKAIKVEQATKPSFERGRHGPPPPPRSRGPPRGFGAGRGGSGGTRGPPSRGGHMDDGGYSMNFNMSSSRGPLPVKRGPPPRSGGPSPKRSAPSGLVRSSSGMGGRAPLSRGRDSYGGPPRREPLPSRRDVYLSPRDDGYSTKDSYSSRDYPSSRDTRDYAPPPRDYTYRDYGHSSSRDDYPSRGYGDRDGYGRDRDYSDHPSGGSYRDSYESYGNSRSAPLTRGPPPSYGGSSRYDDYSSSRDGYGGSRDSYSSSRSDLYSSCDRVGRQERGLPPSVERGYPSSRDSYSSSSRGAPRGAGPGGSRSDRGGGRSRY
What is the function of this protein?
RNA-binding protein which may be involved in pre-mRNA splicing.
What are the official names of this protein?
RNA binding motif protein, X-linked-like-1, Heterogeneous nuclear ribonucleoprotein G-like 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRMD_BACAN
Sequence: MKIDILTLFPDMFTGVFGSSILKKAQEKEAVELRVVNFRDYTTSKHNSVDDYPYGGGAGMVLTPQPIFDAVEDLTKETERKPRVVLMCPQGERFTQKKAEELAEEEHLIFVCGHYEGYDERIREHLVTDEISIGDYVLTGGELASMVITDSVVRLLPGVLGNHASQVEDSFSTGLLEHPHYTRPADFRGMKVPDVLMSGNHKNIDEWRHKESLRRTYTRRPDLLEERELSKQEKKWLEQIKEGK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.