PharMolix/UniProtQA huggingface dataset:
Protein: GCSP_SHESM
Sequence: MTKQTLTQLEQHDLFLRRHIGPDSSQQQEMLNYVGAESLDDLTAQIVPESIRLSQELSIGDSCGEAEGIAYIRGLAKQNQVFKSYIGMGYYGTQVPNVILRNVFENPGWYTAYTPYQPEIAQGRLEAILNFQQVSMDLTGLDLASASLLDEATAAAEAMALAKRVSKAKKANIFFVADDVFPQTLDVVKTRAECFGFEVVVGPAHEAVNHELFGALFQYSNRFGQITDFTDLFAELRAKNVIVTVAADIMALVLLKSPGAMGADVVFGSAQRFGVPMGFGGPHAAFFVARDEHKRSMPGRIIGVSKDTRGNRALRMAMQTREQHIRREKANSNICTAQILLANMASFYAVFHGPQGLKTIASRINRFTDILAAGLQAKGVSLVNNTWFDTISIKGLDVAAVNARALAAEMNLRFDADGIVGVSLDETTLRTDIDALFDVILGAGHGLDVAALDAQIVAQGSQSIPEALVRQDAILTHPTFNRYQSETEMMRYIKRLESKDLALNYSMISLGSCTMKLNAAVEMLPVSWPEFANMHPFCPLDQAKGYTQLIEELSSWLVNVTGYDAVCIQPNSGAQGEYAGLLAIRKYHESRGQAHRNICLIPQSAHGTNPASAQLAGMQVVVTACDKQGNVDLEDLKAKAAEVAENLSCIMITYPSTHGVYEESIREICNIVHQHGGQVYLDGANMNAQVGLTSPGFIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKAHLAPFVAGHVVVKPGRESDNNGAVSAAPYGSAGILPISWMYIKLLGSNGLKKSTQTALLNANYVMKKLSEHYPVLFRGRNDRVAHECIIDLRPIKEASGVTEMDIAKRLNDYGFHAPTMSFPVAGTLMIEPTESESKVELDRFIDAMVSIRAEIAKVEAGEWPADNNPLHNAPHTMADIMDSAFDSRPYSREVAVFPSAAVRTNKFWPTVNRIDDVYGDRNLFCACVPLSDYE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: PD2R_MOUSE
Sequence: MNESYRCQTSTWVERGSSATMGAVLFGAGLLGNLLALVLLARSGLGSCRPGPLHPPPSVFYVLVCGLTVTDLLGKCLISPMVLAAYAQNQSLKELLPASGNQLCETFAFLMSFFGLASTLQLLAMAVECWLSLGHPFFYQRHVTLRRGVLVAPVVAAFCLAFCALPFAGFGKFVQYCPGTWCFIQMIHKERSFSVIGFSVLYSSLMALLVLATVVCNLGAMYNLYDMHRRQRHYPHRCSRDRAQSGSDYRHGSLHPLEELDHFVLLALMTVLFTMCSLPLIYRAYYGAFKLENKAEGDSEDLQALRFLSVISIVDPWIFIIFRTSVFRMLFHKVFTRPLIYRNWSSHSQQSNVESTL
What is the function of this protein?
Receptor for prostaglandin D2 (PGD2).  The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP.  A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).  Involved in PLA2G3-dependent maturation of mast cells.  PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (PubMed:23624557).
What are the official names of this protein?
Prostaglandin D2 receptor, PGD receptor, PGD2 receptor, Prostanoid DP receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: STB2_YEAST
Sequence: MVMADTIATGDKTSQFDGKHMQDLERIYSTRDTLDDNFFGERGQKDANGDYYDELNNEETNYSGSSYYGHSDDSEVVGLIKNDTVSQLPPLDSFIFPDSRALFLLDLGNYADLTYEEIIVHGFEIYIVEQWVACRNLSTLITSYTGNSQDTISGVRVVLPKDTSMWPGRFRLYFEELMEFARPKFTPKGTLFITNLSGVSFGLNLLHVECGDLRTIWKDFEVNFDLKNLHCGGRSANLLCPPTMASLDKFSQLFKIPTNGFIAQYPQMIQQQQPRLPEEEYKTVGNSKCRNTDSKSPVVEMVTLIQISLSYFNLLSKNYQTDGLLCEDTKRAIDEWWETYGKLYLGTEKPRNECTLGPTTVAGLISLILCCYFKLMIENCISSKDPFDEAGFFQGIYNFQKKHGLNKRKSRVYLDPRTLEKLFEVTAKVSSKDIFKLKKMVTSTVQDIIGKGNPINLSHKILTTDLDTLIHNIHGGSVGLLWKGKGHPRKCCTDISNEEFLKFNYQRGDPDGQIREREMLLEKFRLERIAYAQKHASKKVSSSSLDTSEDIGRTNAMPSSATVSSMFPNYDNTKYAYNFGINKLYQGEYYRRNSFPYCKDRTHDNIYEDLSELKEKSSRLYRCNSSSAVQNIVEKWDLPFDPSVVRIARDLLRMKYDIQAQQHIQEMDEHYMGKLNKEGTVGQYSKFNERYKRLQELYKKYSDGAKVFEGRFEDIDNKQQLLLHEMQELNSLSSRLKYDMRILEVRVRDIESSVAQFDSKLIGLKSSLQGQGKTGICSAIDPKSDKDEYDRCVNDLMTTNNPTYEALCLKMLSRRYFKDLKNDTVGWFRWLFGNNSLHNNASEDDRGIRV
What are the official names of this protein?
Protein STB2.
What is the protein family that this protein belongs to?
To yeast STB6.
Protein: GATA_STRAW
Sequence: MTDTNVNIIRLTAAEIAAKVASGELTAVQVTEAHLARIDAVDEKVHAFLHVDREGALAQARAVDEKRERGEKLGPLAGVPLALKDIFTTEGIPTTVGSKILEGWIPPYDATLTKKLKAADVVILGKTNMDEFAMGSSTENSAYGPTGNPWDLSRIPGGSGGGSSAALASFEAPLAIGTDTGGSIRQPAAVTGTVGVKPTYGAVSRYGMVAFSSSLDQGGPCARTVLDAALLHEVIAGHDPLDSTSIDAPVPPVVEAARNGSVEGMRVGVVKQFRGEGYQAGVLQRFDESVALLKELGAEIVELDCPSFDLALSAYYLIAPSECSSNLARFDGLRYGVRVGDDGTRSAEEVTALTREAGFGDEVKRRIMLGTYALSSGYYDAYYGSAQKVRTLITRDFEKSFEQVDVIVSPTTPTTAFPIGERADDPMAMYLADLCTIPTNLAGNAAMSLPCGLAPEDNLPVGLQIIAPALKDDRLYKVGAAVEAAFVEKWGHPLIEEAPSL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS14_CHLPD
Sequence: MAKKSIIARNEKRKRLVEKYAAKREELIKAGDYEALRKLPRDSAATRVRSRCTLTGRGRSVYAKFGLCRHMFRKFALEGKLPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: NQRA_VIBPA
Sequence: MITIKKGLDLPIAGTPSQVINDGKTIKKVALLGEEYVGMRPTMHVRVGDEVKKAQILFEDKKNPGVKFTAPAAGKVIEVNRGAKRVLQSVVIEVAGEEQVTFDKFEAAQLSGLDREVIKTQLVESGLWTALRTRPFSKVPAIESATKAIFVTAMDTNPLAAKPELIINEQQEAFIAGLDILSALTEGKVYVCKSGTSLPRSSQSNVEEHVFDGPHPAGLAGTHMHFLYPVNAENVAWSINYQDVIAFGKLFLTGELYTDRVISLAGPVVNNPRLVRTVMGASLDDLTDSELMPGEVRVISGSVLTGTHATGPHAYLGRYHQQVSVLREGREKELLGWAMPGKNKFSVTRSFLGHLFKGQLFNMTTSTNGSDRSMVPIGSYERVMPLDMEPTLLLRDLCAGDSDSAQALGALELDEEDLALCTFVCPGKYEYGQLLRECLDKIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: FTSW_MOREP
Sequence: MHKTEAQTYLLYDRTLLLLTMGLVGIGLVMVISTSMPIGVRLSEDPFYFARRYAFYLGLAVVLSLVTLGIPMASWQRGSSLILLITLIMLLLVLIAGQSVNGAVRWLALGPWRIQPAELSKLALFCYLASYLVRKAEEVRTNFWGFCKPIGVMVLLAILLLAQPDLGTVLVLFITTLAMLFLAEAKIWQFLPIIGTGILAVMLLIIAKPYRRRRVTSFLNPWDDPFGRGYQLTNSLIAFGRGELWGQGLGNSIQKFEYLTEAHTDFICSILGEELGYFGVLLALLMVFLVAFRAMSIGRKALAINQIFSGFLACSIGIWFSFQTMVNVGAAAGMLPTKGLTLPFISYGGSSMLIMLTAIVLLIRIDFETRLAKLQAFVR
What is the function of this protein?
Peptidoglycan polymerase that is essential for cell division.
What are the official names of this protein?
Probable peptidoglycan glycosyltransferase FtsW, PGT, Cell division protein FtsW, Cell wall polymerase, Peptidoglycan polymerase, PG polymerase.
What is the protein family that this protein belongs to?
Belongs to the SEDS family. FtsW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Localizes to the division septum.
Protein: MET27_HUMAN
Sequence: MAQEEGGSLPEVRARVRAAHGIPDLAQKLHFYDRWAPDYDQDVATLLYRAPRLAVDCLTQALPGPPHSALILDVACGTGLVAAELRAPGFLQLHGVDGSPGMLEQAQAPGLYQRLSLCTLGQEPLPSPEGTFDAVLIVGALSDGQVPCNAIPELHVTKPGGLVCLTTRTNSSNLQYKEALEATLDRLEQAGMWEGLVAWPVDRLWTAGSWLPPSWRWYPASLPRMASSPALSTCTESGRRPRLRK
What are the official names of this protein?
Methyltransferase-like protein 27, Williams-Beuren syndrome chromosomal region 27 protein.
Protein: ECFA1_MESH7
Sequence: MIKVSDVCFSYTNNMDQLVLKNINVVFEKGKYYAILGHNGSGKSTFSKILSGIFKPQKGSIEVDGVLLNKENLTKIRKKIGIIFQNPDNQFVGATVEDDIAFSLENINEDPKKMSQIIANLAAKVQMESYLDREPQFLSGGQKQRVAIASVLALNPEIIIFDEITSMLDPRGKYDVVKILDDLRKDKTKTLISITHNMNEAILADEIIVFANGGIIAQGDPKLILNDKNIIEKAKIDSPFIYKISSALKLVSPTYDENELLEQLWKLKQKTS
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS5_LACLM
Sequence: MAENRRNDREQSEFEERVVSINRVTKVVKGGRRLRFAALVVVGDRNGRVGFGTGKAQEVPEAIRKAIEAAKKNLITVPMVGTTLPHEALGVFGGGKILLKPAVEGAGVAAGGAVRAVLELAGVADVTSKSLGSNTPINVVRATVDGLTQLKRAEEVAALRGKSVSDFA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RS3A_THEPA
Sequence: MAVGKNKRVSKGKKGAKKKVIDPFSRKEWYNLKAPVTFNVRNFGQTLVTKTVGTKLATDGLKGRVFEMSLADLNADEDQAYRKIKLSCEDVQGRNCLTDFHGTSVTRDKLCSLIRKNYSLIEAFADVKTLDGYNLRLFCVGYTKRRPGQLKSTCYVRTSKVRLIHKKMVSVMTNEASNSTLKELVKKVIPESIGKEIEKACKSIFPLQNVLVRKIKVLKKPKFDLTKLMESHNYSGDEEGRTLKVKESENATNLLTAELQSS
What are the official names of this protein?
40S ribosomal protein S3a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOG1_ASPCL
Sequence: MAEFVRAQIFGTTFEITSRYTDLQPVGMGAFGLVCSARDQLTGQPVAVKKIMKPFSTPVLSKRTYRELKLLKHLRHENIISLSDIFISPLEDIYFVTELLGTDLHRLLTSRPLEKQFIQYFLYQILRGLKYVHSAGVVHRDLKPSNILINENCDLKICDFGLARIQDPQMTGYVSTRYYRAPEIMLTWQKYDVEVDIWSTGCIFAEMLEGKPLFPGKDHVNQFSIITELLGTPPDDVIQTICSENTLRFVKSLPKRERQPLANKFKNADPDAVDLLERMLVFDPKKRIRATEALAHEYLSPYHDPTDEPEAEEKFDWSFNDADLPVDTWKIMMYSEILDFHNIDQGNDASQALAEGLGQGQQNFA
What is the function of this protein?
Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment.  Controls osmotic regulation of transcription of target genes (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase hog1, MAP kinase hog1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSBH_NOSP7
Sequence: MAQRTRLGDILKPLNSEYGKVAPGWGTTPVMAVFMALFFVFLLIILQLYNRSLLVQDVLVDWRSLGR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CYB_PHYAH
Sequence: MTNIRKTHPLLKIINSSFVDLPAPSSLSSWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWVLRYLHANGASMFFICLYLHIGRGLYYGSYMFTETWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGMDLVQWIWGGFSVVKATLTRFFPFHFLLPFIVAALVMVHLLFLHETGSNNPTGIPSDPDMIPFHPYYTIKDILGFLIMLTALSTLVLFSPDLLGDPDNYMPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAIVPLLHTSKQRSMMFRPLSQCLFWFLVAVLLTLTWIGGQPVEHPYVIIGQVASVLYFLILLVFMPLTSIVENYLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPICE_XENLA
Sequence: MSYLRASRTSSNLSLAKKPSKTRKKLQARKEWDSSVNDLTVFRATNEELEHRREIHRSKNQWLARWELQNKANYKQSEKENSTQFENSRLALMKEILSDQYLMNDVLERSDRALAVVKDLFGDAPRRHTGFPNVTMAPSCDLETSRAPIVRKKDPPTQLSILSESVMDSQAINEVDKSLSRSEYSDSEAEVSISIQPNMKAERVQQLLTGEGPKSEAFITPHKSEGDPSQTQCALNATTAVNRVKVRRTEEESPKPEESDSIIGRVLNPHGKANKRISLKGKKKRTTNQSQTKDFSTFKASERDLTTSNQSSLGLLNSMIMEVEQDLAEYERQTGREVLSAPPAHGLTGFTLSLVSSLKRVVSYLKESDLLLQREVRERQNLQGELVEQRLMLDALTAEILSLKEGGNIHENHSQTKQCPEVDGDKLTSITQEAKTFPGLNGETCRTSADCGLSKVNQFMDSQDVQDTDEKHSRLGVSKDEFGARLYPQGRPAEEPRLASALPSHVFQQAVLLSPPRQKTVGNLSSHSAVPKRAANRLPSPPADLMTAPVEIEWPESKLFQRSINYKNTAALIERGTMVPGQENSKHVYSSAQGSERVNQHPTESTKEVQGLEIGESQINPLQNEDLVSQMQQLALQNAALKAQLEQIHFSPEGNAPEEAAAEQLHNPEPATDTPARAALVPVSLEMRIAELNRQSAEARNKLLKLIEQQKQSIVVSPTLSPITPQGRRTGSSLDTTPLSSCSTSGRRSSGASNKSESISTSVGSLRSASTGRRSQAANDRGEGWFALSAHIS
What is the function of this protein?
Regulator required for centriole duplication.
What are the official names of this protein?
Spindle and centriole-associated protein 1, Coiled-coil domain-containing protein 52.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle.
Protein: COBT_HALH5
Sequence: MQKVKEMIGSINELDTKAQQQMEQHLNTLTKPLGSLGLLESLAIKIAGITGHTQPEIDPATVIVMVADHGVAAEGVSAYPSEVTQQMVHNFITGGAAINVLSRVSNASVQIVDIGVNGTLQLPGLINKNVRHGTNNMAQGPSMEREEAIAAIEVGIEVAQAAIQNGAKLLALGEMGIGNTTASSAMLAALEQVPVEQIVGFGTGLSHEGKEKKVAVIKRAIEVNQPNAADPIDVLAKVGGLEIAGLAGIVLGAAAWRIPVLVDGFITAVAALTAVRIAPLCVHYLIASHQSVEPGHVCVNKLLGLTPLVNLNLRLGEGSGTAIALPIVRSAIRIAHEMATFEQAGVSGAIEDVGKEK
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: TYPH_SHESA
Sequence: MFLAQEIIRKKRNGLALSTEEIQFFVKGITTNAVSEGQIAALGMAVYFNDMNMDERIALTTAMRDSGTVLNWQSLGLNGPVIDKHSTGGVGDVISLMLGPMAAACGGYVPMISGRGLGHTGGTLDKFDAIPGYQTEPSSELFRKVVKDVGVAIIGQTGDLVPADKRFYSIRDNTATVESISLITASILSKKLACSLDALAMDVKVGSGAFMPTYEASEELARSIAAVANGAGTKTTALLTDMNQVLASCAGNAVEVKEAIDFLTGAYRNPRLYAVTMGLCAEMLLLGGLASDEADARAKLNRVLDNGRAAEIFGKMVSGLGGPVDFVENYSKYLPQSQIIRPVFADTQGYAYSMDTRELGLAVVTLGGGRRKPGDALDYSVGLTQVCALGDKIDASTPIAVIHAQSEEAFAQAEEAVKKAIHIDEVAPEKTPEIYAYIRASDL
What is the function of this protein?
The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
What are the official names of this protein?
Thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
Protein: Y1126_ARCFU
Sequence: MKLMQIGVIGAGECDEETYRIAYRVGELIAEKGHVLINGGLGGVMEASAKGAKSKGGLVVAILPRKKDLCNDFADIRIATDMGHARNVIIVHSSDALISVGGGYGTISEIAIALKEGKRVASLKPPVVIEGMRVFETPEEAVNYCISSSVK
What are the official names of this protein?
Uncharacterized protein AF_1126.
Protein: CNBL8_ARATH
Sequence: MLAFVKCFSLKRAKHPRGYEDPHVLASETPFTVNEIEALHDLFKKLSTSIINDGLIHKEEFLLALFRNGSMQNLFADRVFYMFDRKRNGVIEFGEFVRSLSIFHPYTPEHEKSAFMFKLFDLHGTGFIEPHELKKMVGALLGETDLELSEESIEAIVEQTMLEVDTNKDGKIDEEEWKELVAKNPSILKNMTLPYLKEVTLAFPSFVLDSEVED
What is the function of this protein?
Acts as a calcium sensor.  CBL proteins interact with CIPK serine-threonine protein kinases.  Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner.
What are the official names of this protein?
Calcineurin B-like protein 8.
What is the protein family that this protein belongs to?
Belongs to the calcineurin regulatory subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cell membrane.
Protein: LLDD_CITK8
Sequence: MIISAASDYRAAAQRILPPFLFHYIDGGAYAEYTLRRNVEDLSEVALRQRVLKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAALRRYWQAATHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADSVLLGRAYLYALATAGQAGVANLLDLIEKEMKVAMTLTGAKSISEISRDSLVQELGKSLPAALAPLTQGDAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LON_SYNAS
Sequence: MEVPMPESTINEDSKIFKLPEILPIMPIFHTVAFPKMMFPMDIVGNRFIQLVDEAMAKDRLLGLVLTRKAPSAEGPLCQCEDLHRVGTCVSILKLAKQAGEKAQLVVQGLARFRIVEFLEEEPYIQARVEKIEADILIKDLEIEALMANLSTLFDRVIKLSPFLPQEFAAMAKSIQEPGDLADIIASIVNASVEDKQKILETLDIRQRLREITLIVNHQLEILELGSKIQSQVQEDIDKSQRDFYLRQQLKAIREELGESDENRVEVAEYRKKIEEKMLTEEARKEAFRELDRMSRMHPASAEYSVATTYLDWITSLPWNERTQDNQDIRQARRILDEDHYGLDKAKKRIIEYLAVRKLKPDTKGPILCFVGPPGTGKTSLAQSIARALGRKFYRISLGGVHDEAEIRGHRRTYVGALPGRIIQGIRRAESSNPVFVLDEIDKVGSDFRGDPSSALLEVLDPEQNFAFMDHYLGVAFDLSHVTFITTANILDTIPPALRDRLEVIELPGYTQDEKLRIAERYLIPRQREANGLTPEQIKFTRGAARLIISGYTREAGVRNLEREIAAVCRGVASQIAEGEISSALISARDIHRYLGPVRMISDARERISKPGIAMGLAWTPTGGDLLFVEATAMKGRKGLTLTGQLGEVMKESASAALSFIRSNAVKIGIPVDFFEETDIHIHVPAGAIPKDGPSAGVTMLAALASLLTNRTVKNDLAMTGEITLRGLVLPVGGIKEKVLAAHRAGIKTIILPKWNRKDLEEIPSKVRKEMNFVFVNDMREVLNIALSRK
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress.  Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long.  Binds to DNA in a double-stranded, site-specific manner.
What are the official names of this protein?
Lon protease, ATP-dependent protease La.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM3_BACCR
Sequence: MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKNGASFKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDNDVITEHLDDTLCVPAVGQGALAIECREDDKDLLQLLAHINDTITERTVAAERVFLHKLEGGCQVPIAGYATLTENDAIELTALVGSMDGSVLLKETVVGTNPEEVGLEAADRLIKQGAKELILAANKEQQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: FA72A_BOVIN
Sequence: MSTSSCSFKDRRVSILCCKFCKQVLSSRGMKAVLLADTEIDLFSTDIPPTNAVDFIGRCYFTEICKCKLKDIACLKCGNIVGYHVIVPCCSCLLSCNNGHFWMFHSQAVYGINRLDSTGVNFLLWGNLPEVEENTDEDMLDISAEECIR
What is the function of this protein?
May play a role in the regulation of cellular reactive oxygen species metabolism.  May participate in cell growth regulation (By similarity).
What are the official names of this protein?
Protein FAM72A.
What is the protein family that this protein belongs to?
Belongs to the FAM72 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: GPDA_FRATO
Sequence: MQKNILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHKYLPSIEKFPSRLKAIQDWQANIIEFDSILVATPSSGFKNTILELKECILPQQNIISATKGFCHDSYALLSEIAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINYARYVQELFSNENFRCYTTTDIIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGANSETFIGLSCLGDLLLTCSDNQSRNRRFGLYLGQGMTIQQALKEVNNVVEGYFTAKAVYNFAKKHNVEMPLVFATYRILYEAADPRDIVKELMTRQLKNEN
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLA_RALSO
Sequence: MFVLKARHLMAAGLVSLAAWSAGAQAGAIEQLNAFVSNVTTARGEFVQRQVKGGANGSPLRVAGTSSGDFTFSRPGRFVWRYLKPYEQQLSADGQMLYIYDKDLSQVTERKLDASLGSSPAAILFGSNDLAKNFVLKEGGTKDGIDWVELTPKAKDTQFERVAIGFRAGELEGMELRDAFGNTTLLTFSHIQKNPQLPASAFRFVPPKGADVIKQ
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SNT1_YEAST
Sequence: MGYPPPTRRLGDKKRYHYSNNPNRRHPSAVYSKNSFPKSSNNGFVSSPTADNSTNPSVTPSTASVPLPTAAPGSTFGIEAPRPSRYDPSSVSRPSSSSYSSTRKIGSRYNPDVERSSSTTSSTPESMNTSTITHTNTDIGNSRYSRKTMSRYNPQSTSSTNVTHFPSALSNAPPFYVANGSSRRPRSMDDYSPDVTNKLETNNVSSVNNNSPHSYYSRSNKWRSIGTPSRPPFDNHVGNMTTTSNTNSIHQREPFWKANSTTILKSTHSQSSPSLHTKKFHDANKLDKPEASVKVETPSKDETKAISYHDNNFPPRKSVSKPNAPLEPDNIKVGEEDALGKKEVHKSGREIAKEHPTPVKMKEHDELEARAKKVSKINIDGKQDEIWTTAKTVASAVEVSKESQKELTRSVERKESPEIRDYERAYDPKALKTDVTKLTVDNDNKSYEEPLEKVEGCIFPLPKAETRLWELKNQKRNKIISEQKYLLKKAIRNFSEYPFYAQNKLIHQQATGLILTKIISKIKKEEHLKKINLKHDYFDLQKKYEKECEILTKLSENLRKEEIENKRKEHELMEQKRREEGIETEKEKSLRHPSSSSSSRRRNRADFVDDAEMENVLLQIDPNYKHYQAAATIPPLILDPIRKHSYKFCDVNNLVTDKKLWASRILKDASDNFTDHEHSLFLEGYLIHPKKFGKISHYMGGLRSPEECVLHYYRTKKTVNYKQLLIDKNKKRKMSAAAKRRKRKERSNDEEVEVDESKEESTNTIEKEEKSENNAEENVQPVLVQGSEVKGDPLGTPEKVENMIEQRGEEFAGELENAERVNDLKRAHDEVGEESNKSSVIETNNGVQIMDPKGAVQNGYYPEETKELDFSLENALQRKKHKSAPEHKTSYWSVRESQLFPELLKEFGSQWSLISEKLGTKSTTMVRNYYQRNAARNGWKLLVDETDLKRDGTSSESVQQSQILIQPERPNINAYSNIPPQQRPALGYFVGQPTHGHNTSISSIDGSIRPFGPDFHRDTFSKISAPLTTLPPPRLPSIQFPRSEMAEPTVTDLRNRPLDHIDTLADAASSVTNNQNFSNERNAIDIGRKSTTISNLLNNSDRSMKSSFQSASRHEAQLEDTPSMNNIVVQEIKPNITTPRSSSISALLNPVNGNGQSNPDGRPLLPFQHAISQGTPTFPLPAPRTSPISRAPPKFNFSNDPLAALAAVASAPDAMSSFLSKKENNN
What is the function of this protein?
Part of the Set3C complex, which is required to repress early/middle sporulation genes during meiosis.
What are the official names of this protein?
Probable DNA-binding protein SNT1, SANT domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.