PharMolix/UniProtQA huggingface dataset:
Protein: PRGR_COLGU
Sequence: MTELKSKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFQGSQTSDTLPEVSAIPISLDGLLFPRLCQGQDPPDKKTQNQQSLSDVEGAYSRAEATRGTGGSSSRPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGGKTEDSSGTAAAHKVLPRGLSPSRQLLLPTSGSPHWSGAPVKPSPQPTAVEVEEEDGSESEDSAGPLLKGKSRVLGGAAAGGGAAAVPPGAAAGGVGLVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTMMDFIHVPIVPLNHALLAARTRQLLEDESYDGGAGAASAFAPPQSSPSASSTPVAVGDFPDCAYPPDAEPKDNAYPLYGDFQPLALKIKEEEEGAEASARSPGSYLVAGANPAAFPDFPLGPPPQLPPRAPPSRPGEAAVTAAPASASVSSASSPGSTLECILYKAEGALPQQGQFAPPPCKAPGAGGCLLPRDGLPSTSASAAAAAGAAPTLYPALGLNGLPQLGYQAAVLKEGLQQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVALPQPVGIPNESQVLSQRFTFSPGQDIQLIPPLIKLLMSIEPDVIYAGHDNSKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: RLMH_ECOL5
Sequence: MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRGKNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLIGGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_MYCGA
Sequence: MKTELIAQLKKTIITVKDFPKPGILFYDITPILLDPKLFDQVISVMAEVAKKSNADMIASPESRGFLFGVPLANKLKLPFVLVRKQNKLPRATFSASYDLEYGKNNVIEIHQDAIKPNSKVMIVDDLLATAGTVDAISRLVKQAKSEVVSYSFLIRLKDLGGIDKLDQTKPIDYILEY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMG_PSEU2
Sequence: MPLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAQAGLSLPSRVLVLNDSFGALAASLAPHATVISSTDSFLAAQALEKNLARNGMSYDAVPHIPASEALQGPFDWVLIRVPKTLALLEEQLIRLQGQLAPGARVIAAAMVKHLPRSAGDLLEEYVGPVQASLAVKKARLLFATPQPMEVRTSPYPTRYRLEEPAIELLNHANVFCRDGLDIGTRAFLPHLPKNLGTARVADLGCGNGVLAIASALDNPQAHYTLVDESFMAVKSAAENWRATLGDRDVRVRAGDGLEMQEPDSLDVVLCNPPFHQQQVVGDFLAWRMFLQARAALVTGGALYIVGNRHLGYHTKLSRLFRGVEQVAATPKFVILKARK
What is the function of this protein?
Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase G, 23S rRNA m2G1835 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RlmG.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROL6_CAEEL
Sequence: MTLTTATSGAIVFSGATLLVSLFAAASLYSQVSNIWNELDAEIANFRSLTEDMWVDMVKLGAGTASNRVRRQQYGGYGATGVQPPAPTPNPYGGYGASQPAPPEKFPDGIPNGGNQPKFPGGGFPDGPFPNGGGPRGGNQCQCTVENSCPPGPAGPEGEEGPDGHDGQDGVPGFDGKDAEDVQNTPPTGCFTCPQGPLGPQGPNGAPGLRGMRGARGQPGRPGRDGNPGMPGDCGPPGAPGSDGKPGSPGGKGDDGERPLGRPGPRGPPGEAGPEGPQGPTGRDAYPGQSGPQGEPGLQGYGGAAGEDGPEGPPGAPGLPGKDAEYCKCPGREGDAGRSARRHRKFQL
What is the function of this protein?
Nematode cuticles are composed largely of collagen-like proteins (Probable).  The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (Probable).  May play a role in cuticle remodeling in response to the environment (PubMed:32229533).  Involved in body morphogenesis (PubMed:21094156).
What are the official names of this protein?
Cuticle collagen rol-6, Protein roller-6.
What is the protein family that this protein belongs to?
Belongs to the cuticular collagen family.
Protein: AMY4_SCHPO
Sequence: MKLSLKDLALSIILVLGVAPPVQALSAEEWKKQSVYNVMTDRFATSKVVPHCDVKAEKYCGGNWQGIVDHLDYIRDLGFTAISISPVVEQLEGPEYHGEAYHGHRPKNYYRLNPHFGNEEDLKELSDALHGKGMYLMVDVAINHTISEYFEDDYFKNTYFDKTHIDHKCKEHCSCHHDKFPRPVPHNGTKPDHKPWKHEEHCHHGKFPRPVPHNGTKPDHKPWKHEEHCSCHHDKFPRPVPHNGTKPDHKPWKHEEHCSCHHDKFPRPVPHNGTKPDHKPWKHEEHCHHGKFPRPIPHNGTKPDHKPWKHEEHCHHGRFPRPVPHNGTKPDHKPWKHEEHCSCHHDKFSRPVPHNGTKPDHKPWKHEEHCHHGKFLRPVPHNVTKPDHKPWKHEEHCHHGKFPRPVPHNGTKPDHKPWKHEEHCSCHEDHSVHERPSAKGALEDYIQTFVETFQIDGIRFDAMGDKYRKYWPDFCKAAGVFCMGDLKSSDSLKVCDWQNDLEGLSNFPVRESAVKAFLMNNPEGIVDLADKMTDMRGLCVNPLLLGNFVENKDLPRMASISSDPATLKNAIAFVLMGDGIPMMYNGQELAMRGEEVPYNRPAIWEKGFPKRNPYYKFTSTINRFRKAMIESKDGEAFLNMQSDISIVDKRILLLRRGKVITVLNNLGSYYIHFHYTVSAEEHKWMDVLSCKSVPVQDNRQVFMVRNGEPMILYPEESAYEMGLCPSPIQLTEDYNSEGSLSINVEEAQTSKAPEQNRGFTNVLAALLLSLLMIL
What are the official names of this protein?
Alpha-amylase 4, 1,4-alpha-D-glucan glucanohydrolase, Meiotic expression up-regulated protein 7.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MYL11_RAT
Sequence: MAPKKAKRRAAAEGSSNVFSMFDQTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMMKEASGPINFTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLTTQCDRFSQEEIKNMWAAFPPDVGGNVDYKNICYVITHGDAKDQE
What is the function of this protein?
Myosin regulatory subunit that plays an essential to maintain muscle integrity during early development (By similarity).  Plays a role in muscle contraction (By similarity).
What are the official names of this protein?
Myosin regulatory light chain 11, DTNB, Fast skeletal myosin light chain 2, G2, MLC-2, Myosin light chain 11, Myosin regulatory light chain 2, skeletal muscle isoform.
Protein: SECE_MYCLE
Sequence: MSDERYAASDGGGTEVGSGTRGRTTVVTKPATRPQRPTGKRSRQRAANASNTGANVEVEESSTQAAIAKEGKVKKPKKSADRSANPIVFIYNYLKQVVGEMRKVIWPNRKQMLTYTSVVLAFLAFMVALVGLADFGLAKLVLLVFG
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y2671_SHESM
Sequence: MLGWTLMFLVVAIIAGLFGFTGIAGAAAGIAKIIFFLFIVLLVISLLVNALKGKAPRA
What are the official names of this protein?
UPF0391 membrane protein Shewmr4_2671.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SODM2_HALVD
Sequence: MSYELDPLPYEYDALEPHISEQVLTWHHDTHHQGYVNGWNAAEETLAENREAGEFGSSAGALRNVTHNGSGHILHDLFWQNMSPEGGDEPEGALAERIAEDFGSYEAWKGEFEAAAGAAGGWALLVYDSFSNQLRNVVVDKHDQGALWGSHPILALDVWEHSYYHDYGPARGDFVSAFFEVVDWDEPAARYEQAVELFE
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn] 2.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: HPNN_BURM1
Sequence: MVTSLIVRLVAWSVRRPVWVVVLSLLIAAFSGVYVARHFKINTDISKLVDAEPQWAALSQAVDRAFPQRNGTILAVVEAPAPEFATAAAHALTESLQKQAAAGRIGPVAEPGGGPFFEHNGLLFLSPQQVADTTSQLASARPLVNELAKNPSLTGLATTLSTTLGQPLLTGQVKLPSMAKLLSRSAATVDDVLAGKPAAFSWRALVDNDAARQPARAFVTVQPVVNYGALKAGAQTSDVIRETARALDLEKRYGAVVRLTGEQPLADDEFSSVEDGAALNGVVTLLVVFVILWLALRSKRMIASVLVTLFVGLVVTAALGLAMVGSLNMISVAFMVLFVGLGVDFSIQYGVKYREERFRDERIDHALIGAAHSMGMPLALATTAVAASFFSFIPTAYRGVSELGLIAGVGMFVALLTTLTLLPALLRLFAPPGESKTPGFPWLAPVDDYLDRHRKPILIGTLAVVIGALPLLAFLHFDFNPLHLKDPHSESMSTLLALKDSPEAAVNDVTLLAPSLADADAAAKRLDALPEVGRTTTLSTFIPADQPEKRAAIATAASTLLPALTQPPAPPATDAQRVAALKRASDLLGYAAEDHPGPGAAAAQHLSQSLAKLAAADSATRDRAERAFADTLRIALNQLAALLQPQEITRDTLPPPLVRDWVAPDGKALVQISPKVPKGVDPNDDTMLRHFATAVKAAEPGAIGGPISILHSANTIISAFLHAALWSIISITILLWITLRRFGDVLRTLVPLLVSGIVTLEMCVVLGMSLNFANIIALPLMLGVGVAFKVYFVMAWRAGQTGLLHSSLTHAVLFSAATTATAFGSLWLSHHPGTSSMGKLLALALTCTLIGAVVFQPVLMGKPRVKRAKNQSQGINE
What is the function of this protein?
Essential for hopanoid transport from the cytoplasmic to the outer membrane (PubMed:28584102).  Is capable of shuttling hopanoid lipids from the inner membrane to the periplasm, where they probably spontaneously insert to the inner leaflet of the outer membrane, strengthening the cell envelope (PubMed:28584102).  May be a proton-motive-force (PMF)-dependent transporter (PubMed:28584102).  Is critical for multidrug resistance and cell wall remodeling in Burkholderia (PubMed:28584102).
What are the official names of this protein?
Hopanoid transporter HpnN.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
Protein: PBAN_SPOLI
Sequence: MFSPLLFFAVSISCVLANSNEIKDGGSDRGAHSDRAGLWFGPRLGKRSLRISTEDNRQAFFKLLEAADALKYYYDRLPYEMQADEPETRVTKKVIFTPKLGRSLAYDDKVFENVEFTPRLGRRLADDMPATPADQELYRPDPDQIDSRTKYFSPRLGRTMNFSPRLGRELSYDMLPSKLRLVRSTNRTQST
What is the function of this protein?
A hormone that controls sex pheromone production in females and pheromone responsiveness in male.
What are the official names of this protein?
PBAN-type neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the pyrokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1993_COXBN
Sequence: MPSFDIQSELNKHEVSNAVDQANREVATRFDFKGSGATYKYEGNSITLQAETDFQLKQMIDILQNKFAKRQIDVAHMKLEDPIIQHKSAQQTVMLLEGIDQTAAKKIIKLIKDQKLKVQAAIQGEKVRVTGKKRDDLQSVIGLLKEQEIGLPLQFDNFRD
What are the official names of this protein?
UPF0234 protein CBUD_1993.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ABT3A_DANRE
Sequence: MAGKGKTAARTLEDLTLDSGYGGAADSFRSSSVSLCCSDTHLSYAHGGNCWHLTESMHSRHNSLDTVNTVLAEDTEILECSGQCAKLPELEEDVPWSLGEVEGALRKDEELCVGNASREILAKLSALVSRALVRIAREAQRMSLRYARCTKHEIQSAIKMVLSWTISVNCITAALSALSLYNMSTGDKFSRGKSTRCGLIFSVGKFFRWMVDSRVALRIHEHAAIYLSACMESLFREVFTRVQRSALVEKENGVPKFSVESLEQAINNDSELWGLLQPYQHLICGKNASGVLSLPDSLNLHRDQQRAGKTGEGHAYSQAELRTIEQSLLATRVGSIAELSDLVSRAMHHLQPLHIKNPSNGTPVHQNRTGSVHWEPEALYTLCYFMHCPQMEWENPNVEPSKITLHTERPFLVLPPLMEWIRVAVAHTEHRRSFSVDSDDVRQAARLLLPGVDCEPRQLKADDCFCATRKLDAASTEAKFLQDLGFRMLNCGRTDLVKQAVNLLGPDGINSMSEQGMTPLMYSCVRGDEAMVQMLLDAGADINSEVPSSLHKHPSVYPDTRQGTPLTFAVLHGHVPVVQLLLDARANVEGAIQESTENYTETPLQLASAAGNFELVSLLLERGADPLIGTTYRNGISSGPLGEMNSYSLAAAHGHRNVFRKLLSQVEKDKGDVLSLEEMLAEGSEAVERRAPQNEGTLRTGKAKLRALREAMYHSAEHGHVDITIDIRSLGVPWTLHTWLESLRTCFVQQRRPLIQGLLKDFSCIKEDEYTEELITHGLPLMFQILRASKNEVISQQLSVIFTQCYGPFPIPKLTEIKKKQTSRLDPHFLNNKEMSDVTFLVEGKPFYAHKVLLFTASPRFKSLLSNRPAAENTCIEISHVKYNIFQLVMQYLYCGGTESLHIRNTEIMELLSAAKFFQLDALQRHCEIICSKNITNDSCVDIYKHARFLGALELAGFIEGFFLKNMVLLIELENFKQLLYEVPADSPGPGPSYDVLHDLEQTLALRIRSIHLSTSKGSIV
What are the official names of this protein?
Ankyrin repeat and BTB/POZ domain-containing protein 3-A, BTB/POZ domain-containing protein 11-A.
Protein: TXAG5_AGEOR
Sequence: MRTIISLLLLSAMVFAVIEAISLEEGLQLFEGERGCVGENQQCADWAGPHCCSGLRCKELSIWDSRCLG
What are the official names of this protein?
U5-agatoxin-Ao1a, U5-AGTX-Ao1a, AgorTX_A3.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 01 (U2-agtx) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVA_STRZJ
Sequence: MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEDQIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIETKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAMLALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: G3P_DEBHA
Sequence: MAITIGINGFGRIGRLVLRIALQRSDIKVVAVNDPFIAPEYAAYMFKYDSTHGRYKGEVTSKDDSLVIDGQSIKVFGEKDPASIPWGKAGVDYVIESTGVFTTTEGAQKHIDGGAKKVIITAPSSDAPMFVVGVNEQKYTPDLKIVSNASCTTNCLAPLAKVINDKFGIEEGLMTTVHSITATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVIPELNGKLTGMSLRVPTVDVSVVDLTVRLKKSATYEEISEAIKAASNGELKGILGYTEDAVVSTDFLGSDYSSIFDQKAGILLSPTFVKLISWYDNEFGYSTRVVDLLEHVAKASN
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMT3_CAEEL
Sequence: MAGPEGSIFNASAMQIVQIHHYAEGSVTPEVDKLYQDDAVWIISSSFIIFTMHSGFGLLESGSVSAKDEVNIMVKNVVDVVFGGLSYWSCGFGFSYGDIPEWRNPYVGFGKFFYDPTRDYGTRETINQEGWSYASFLFQLSLATTASTIVSGAVAERAKLKSYILLGCIVILIQALPAHWVWDKEGVFYKKGVVDFAGCSAVHLVGGIIGLIATVFLKPRRNRFNEDSVHQMSSPTNALLGTFLLWWGWFGINAGSVWGITGGRWRLGARAAVATIMASIGGGATAITISFVKTKKLQVNFLINGILSSIVSITAICAVSRPWHALVIGSISSVFSIAVLPLLDRLHIDDPVGIVPIHLTSSIWGMIAVGIFCEEDKYLGSATNNRSGLLYSWSFELLWVQLQCTAAILIYSATTGFLALFLISKSPLGLRVTDYEEQIGADVIEHGLAGTNVARYVLEKPLSTRTFQTVTKAITKWKMLAKKKSRQKRMEAAKLKRQEEQETFTNGTAIANGNGNVLHHRTNATESNGTGAPKRSNGPAFNNQITPLAVSSTVSTARNGPSTGRRTESTAIEIEQPIEAVPPEVVAAAVLPPEERPGPSTNSNVSIEASVEKSPSSSTSRRSISIRSSPSIHTVSAISTAAPDSRPSTASATSIISKKSSKNSTVGKFVKAPAPRALSPPDNNPPV
What is the function of this protein?
Involved in the uptake of ammonia.
What are the official names of this protein?
Putative ammonium transporter 3.
What is the protein family that this protein belongs to?
Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ARD_VIBHA
Sequence: MAQLVDEIVFQSGVKLHNRIVMAPMTIQSAFFDGGVTQEMINYYAARSGGAGAIIVESAFVENYGRAFPGALGIDTDSKIAGLTKLADAIKAKGSKAILQIYHAGRMANPEFNGGHQPISASPVAALRDNAETPLEMTKEQIEEMIERFGDAVNRAILAGFDGVEIHGANTYLIQQFFSPHSNRRNDKWGGNIERRTSFPLAVLAKTKQVAEQHNKSDFIIGYRFSPEEIEQPGIRFDDTMFLLDKLATHGLDYFHFSMGSWLRNSIVTPEDQEPLIDKYRKLQSESVAKVPVIGVGGIAQRKDAENALEQGYDMVSVGKGYLVEPTWANKALNDETCAEFADIAQQEALQIPTPLWEIMDYMIVDSAAEALKHQRIKELQNVPIKFNSGEYTAYGRGHNGDLPVTVTFSEDKILDIVVDSSKESDGIANPAFERIPQQILDGQTLNIDVISGATVSSQAVLDGVSNAVDLAGGNSEALRCKAKEAVAWSSKTIEETVDIVVVGGGGAGLSATLTALDKGKSVVLLEKFPAIGGNTVRTGGWVNAAEPKWQGDFPALPGEKETLMLLAKTAESEFSGEYLEDFKVLKAQLDGYFTDLENGKQYLFDSVELHRIQTYLGGKRTDLNGESIYGQYDLVETLTSRSMESIDWLSEKGIDFDRSVVEIPVGALWRRAHKPKRPKGVEFIDKLSKRIQEQNGRIITDTRATDLMVDNGKVVGIKAVQADGTELILHVNHGVVLASGGFGANTQMIKKYNTYWKEIADDIKTTNSPALVGDGIEIGEKAGAELVGMGFVQLMPVGDPKSGALLTGLIVPPENFVFVNKQGKRFVDECGSRDVLSEAFFDNGGLIYMIADENIRQTAANTSDETIEREIKEGIIIQADTLEELAEKIGVPTQELTNTIAQYNACVDAGQDPEFHKSAFGLKVEKAPFYATPRQPSVHHTMGGLKIDTKARVIGKDGEVIQGLYAAGEVTGGIHAGNRLGGNALIDIFTYGRIAGESASDLV
What is the function of this protein?
Catalyzes the NADH-dependent reduction of acrylate to propanoate.  The principal role of ARD in Vibrio seems to be the energy-saving detoxification of acrylate coming from the environment.  May also use acrylate as the terminal electron acceptor for NADH regeneration at oxygen deficiency.  NADPH cannot replace NADH as the electron donor.  Is also able to reduce methacrylate in vitro, but with a much lower efficiency.
What are the official names of this protein?
NADH:acrylate oxidoreductase, ARD, NADH-dependent acrylate reductase.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
Protein: GPMA_STRPC
Sequence: MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIKEAGIEFDLAFTSVLTRAIKTTNLALENAGQLWVPTEKSWRLNERHYGALTGKNKAEAAEQFGDEQVHIWRRSYDVLPPAMAKDDEYSAHKDRRYADLDPALIPDAENLKVTLERAMPYWEEKIAPALLDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFELDEKLNIVKEYYLGGE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: BIOD_LEGPC
Sequence: MKRYFVTGTDTDCGKTFVTNQLVNYFSSSAAIKPIASGCEYSKNQLVNSDALLHQQQNHLPLEIINPWRFRLPVSPHLSAREDGASIDVHKVADYCLNLQLNDIKKLFIEGAGGLMVPLNEQDTWLDFLKLTRIPVILVVGMKLGCINHTLLTQEVLEINKIKCQGWIANCLDQDMLMLDENISTLEAKLKYPLLARTNYGGKISDICLSSL
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUC2F_RAT
Sequence: MFLGPWPFSRLLSWFAISSRLSGQHGLTSSKFLRYLCLLALLPLIWWGQALPYKIGVIGPWTCDPFFSKALPEVAAALAIERISRDMSFDRSYSFEYVILNEDCQTSKALTSFISHQQMASGFVGPANPGYCEAASLLGNSWDKGIFSWACVNHELDNKHSYPTFSRTLPSPIRVLVTVMKYFQWAHAGVISSDEDIWVHTANQVSSALRSHGLPVGVVLTSGQDSRSIQKALQQIRQADRIRIIIMCMHSALIGGETQTHFLELAHDLKMTDGTYVFVPYDVLLYSLPYKHSPYQVLRNNQKLREAYDAVLTITVESHEKTFYEAFTEAAAGGEIPEKLDSHQVSPLFGTIYNSIYFIAQAMSNALKENGQASAASLTRHSRNMQFYGFNQLIRTDSNGNGISEYVILDTNGKEWELRGTYTVDMETELLRFRGTPIHFPGGRPTSADAKCWFAQGKICQGGIDPALAMMVCFALLLALLSINGFAYFIRRRINKIQLIKGPNRILLTLEDVTFINPHFGSKRGSRASVSFQIISEVQSGRSPRLSFSSGSLTPATYENSNIAIYQGDWVWLKKFPPGDFGDIKSIKSSASDVFEMMKDLRHENVNPLLGFFYDSGMFAIVSEFCSRRSLEDILTQDDVKLDWMFKSSLLLDLIKGMKYLHHREFIHGRLKSRNCVVDGRFVLKVTDYGFNNILEMLRLSEEEPSEEELLWTAPELLRAPGGIRLGSFAGDVYSFAIIMQEVMVRGAPFCMMDLSAKEVIDRLKMPPPVYRPVVSPEFAPPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGSRHAAEIANMSLDILSSVGTFKMRHMPEVPVRIRIGLHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVSLSTVTILRTLSEGYEVELRGRTELKGKGTEETFWLVGKKGFTKPLPVPPPVGKDGQVGHGLQPAEIAAFQRRKAERQLVRNKP
What is the function of this protein?
Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors.  Plays an essential role in phototransduction, by mediating cGMP replenishment (PubMed:7831337).  May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity).
What are the official names of this protein?
Retinal guanylyl cyclase 2, RETGC-2, Guanylate cyclase 2F, retinal, Guanylate cyclase F, GC-F, Rod outer segment membrane guanylate cyclase 2, ROS-GC2.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Photoreceptor outer segment membrane; Single-pass type I membrane protein.
Protein: YOPP_BACSU
Sequence: MQNKIKQLKNYAVYDDIEGFLINKDIRSSSGNSNYMMPSSTRRVSNTRKNYEGDIKQFFSVIKGKDVKSLVPDDLVVSKSELSNYVKYLQEKGLVNNSINRKMTSLKMLYTYLEHDYKDYIDLSVFNTVERLKTVTKNWDKTTQTEAERIAQDMYINERQKPLMKKLFVKFAIRTSFRVSAILRVRWKDIQLDESTGHYIVTVIDKGSQVVSTGINQVFYEELLQLKEEDDSETELVFQGLSEQSLRHSLKRSKKRLGIPPERELVLHSFKGVGIDYVYENSGHDLLAAKEQGNHKNTLTTERYMSRKINIANSAGVTMDEKIDLNPLYEATQEDFISFFENADLVTLKKFIKHVNER
What is the function of this protein?
Probable recombinase that does not seem to have a role in chromosome dimer resolution per se but rather may have some facilitative role during chromosome partitioning in general.
What are the official names of this protein?
SPbeta prophage-derived probable integrase/recombinase YopP.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: RT27_MOUSE
Sequence: MAAPMVRCGMLLARRLDASRLCLAGKRCLLSAAYVDSHQWEAREKEEYHLADLASLMDKAYERKLPVSSLSISRFVDNIASREDLDSAEYYLYKFRHSPNCWYLRDWTIHSWIRQCLKYGAQDKALYTLVNKVQYGIFPDNFTFNLLMDYFIKKGNYKDALSVVFEIMMQEAFDVPSTQFLSLYVLYRCLAEKTELTWEEERDFGASLLLSGLKQRNTVGLSSQLYGYALLGKVELQRGVRAVYHGMPLMWTPGYLDRALQVMERVASSPEDLKLGREVLDVLDGVLKVVTSPDVQTSEAQPQEGEDGLGSANLVEQLDTEEPEQSKLPRYLERFQASRSKLQELNRVESESLLTLTTQLVKEKLPACEAEDLATYEQKLREWHLERVQLIQREQEQREKAKQEYQALSAAEKAA
What is the function of this protein?
RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis.  Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron transport chain.  Binds to the mitochondrial 12S rRNA (12S mt-rRNA) and tRNA(Glu).  Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues.
What are the official names of this protein?
28S ribosomal protein S27, mitochondrial, MRP-S27, S27mt, Mitochondrial ribosomal protein S27.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS27 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.