PharMolix/UniProtQA huggingface dataset:
Protein: PAND_SALSV
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFLDASGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAEVGDIVIIASFVTMSDEEARTWRPKVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_PSEMY
Sequence: MSAADRLLEAWYRGHPALALLRPLEWLYRRVVQGKRARFLAGQGDIYRAPVPVLVVGNITVGGTGKTPLILFLIEHCRARGLKVGVVSRGYGATPPSLPWRVRADQSAAQAGDEPLLIVQRTGVPLMIDPDRSRAVRALLAEEPLDLILCDDGLQHYRLARDLELVLIDAARGLGNRRCLPAGPLREPAERLAEVDAVLSNGAETDSAEGYAFRLQPSALVNLVSGERLGLEHFPPGQAVHAVAGIGNPQRFFNTLEALNWRPVPHPFADHAQYDAAQLSFEPPLPLLMTEKDAVKCRAFAAADWWYLAVDAVPTPAFVDWLDKELARLIPGS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: GLMU_DESVH
Sequence: MASTTGALILAAGKGTRMHSDKPKVLQTILGEPMLRFVMDALAPVFGDRVWTVVGHRADMIYAAFAGEDARFVVQEQQLGTGHALQMAWESLRAAGLDRVVVVNGDTPLLATETIDFFLKESAEADIAFMTLTLPDPGAYGRVVRHNGHVAAIVEAKDYDEALYGPEPSEINTGIYALRLDAVESLLPRLTNANRSGEYYITDLVGLAVAERMNVLGIQCGEDPNLLGVNNPAELIRSEALLRTRLVIGHIEGGVLIHAPETVRISPRATIEPGAEIYGPCEIYGTSRIARGAVVHSHCWLRNAEVESGSEVKSFSHLEGATVGKGCSVGPFARLRPGAVLDEEARVGNFVEMKKARLHKGAKAGHLTYLGDADVGAGANIGAGTITCNYDGKNKHRTVIGAGAFIGSNTALVAPVTVGDGSLVGAGSVITKDVPEASLAIARGRQTNLPRKPKA
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_PARDP
Sequence: MARVTVEDCVDKVPNRFDLVMLAAHRAREIAAGSPLTVDRDNDKNPVVSLREIADETQPVDDLRERMIEAQQTQIEVDEPEEDAMALLLGAEMDRPKPADEESEERMLRMMLEAQGRN
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TPS03_ARATH
Sequence: MPKRQAQRRFTRKTDSKTPSQPLVSRRSANYQPSLWQHEYLLSLGNTYVKEDNVERVTLLKQEVSKMLNETEGLLEQLELIDTLQRLGVSYHFEQEIKKTLTNVHVKNVRAHKNRIDRNRWGDLYATALEFRLLRQHGFSIAQDVFDGNIGVDLDDKDIKGILSLYEASYLSTRIDTKLKESIYYTTKRLRKFVEVNKNETKSYTLRRMVIHALEMPYHRRVGRLEARWYIEVYGERHDMNPILLELAKLDFNFVQAIHQDELKSLSSWWSKTGLTKHLDFVRDRITEGYFSSVGVMYEPEFAYHRQMLTKVFMLITTIDDIYDIYGTLEELQLFTTIVEKWDVNRLEELPNYMKLCFLCLVNEINQIGYFVLRDKGFNVIPYLKESWADMCTTFLKEAKWYKSGYKPNFEEYMQNGWISSSVPTILLHLFCLLSDQTLDILGSYNHSVVRSSATILRLANDLATSSEELARGDTMKSVQCHMHETGASEAESRAYIQGIIGVAWDDLNMEKKSCRLHQGFLEAAANLGRVAQCVYQYGDGHGCPDKAKTVNHVRSLLVHPLPLN
What is the function of this protein?
Predominantly involved in sesquiterpenes (C15) biosynthesis.  Using FPP as substrate, the major product is (E,E)-alpha-farnesene with minor amounts of (Z,E)-alpha-farnesene and (E,E)-beta-farnesene.  Using GPP as substrate, could also be able in vitro to synthesize monoterpene (C10) with (E)-beta-ocimene as the major product and with (Z)-beta-ocimene and myrcene as minor products.
What are the official names of this protein?
Terpenoid synthase 3, chloroplastic, AtTPS03, (E)-beta-ocimene synthase, (E,E)-alpha-farnesene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsb subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Plastid, chloroplast stroma.
Protein: MERA_ENTAG
Sequence: MTTLKITGMTCDSCAAHVKEALEKVPGVQSALVSYPKGTAQLAIEAGTSSDALTTAVAGLGYEATLADAPPTDNRAGLLDKMRGWIGAADKPSGNERPLQVVVIGSGGAAMAAALKAVEQGAQVTLIERGTIGGTCVNVGCVPSKIMIRVAHIAHLRRESPFDGGMPPTSPTILRERLLAQQQARVEELRHAKYEGILDGNSAITVLHGEARFKDDQSLIVSLNEGGERVVMFDRCLVATGASPAVPPIPGLKESPYWTSTEALASDTIPERLAVIGSSVVALELAQAFARLGSKVTALARNTLFFREDPAIGEAVTAAFRAEGIEVLEHTQASQVAHMDGEFVLTTTHGELRADKLLVATGRTPNTRSLALEAAGVAVNAQGAIVIDKGMRTSSPNIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIETDSRLLTLDNVPRALANFDTRGFIKLVIEEGSGRLIGVQAVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG
What is the function of this protein?
Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase.  MerA protein is responsible for volatilizing mercury as Hg(0).
What are the official names of this protein?
Mercuric reductase, Hg(II) reductase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
Protein: E1BS_ADEM1
Sequence: MLPVYPFLAPVFDTFESTRALFLEATLSLQEPWWFRLLSFFRSPRYTGLADVVRAIACEREADFTAITPSSLIEDIAEGRFVMLVGLMEYLRFDTAGQGIVSFAFLSYLIDRVTKQSPLAHFTVVEVVSLVVWRTVKLSRRRERRWVSQLSTLAEEDEDEEGTTLTTEAEQESSA
What are the official names of this protein?
E1B protein, small T-antigen, E1B 19 kDa protein, E1B-19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 19 kDa protein family.
Protein: SRPK3_HUMAN
Sequence: MSASTGGGGDSGGSGGSSSSSQASCGPESSGSELALATPVPQMLQGLLGSDDEEQEDPKDYCKGGYHPVKIGDVFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQAGAPPPSRSIVSTAPQEVLQTGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAATQAEDSGLRLDGGSGSTSSSGCHPGGARAGPSPASSSPAPGGGRSLSAGSQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP
What is the function of this protein?
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains.  Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro.  Required for normal muscle development (By similarity).
What are the official names of this protein?
SRSF protein kinase 3, Muscle-specific serine kinase 1, MSSK-1, Serine/arginine-rich protein-specific kinase 3, SR-protein-specific kinase 3, Serine/threonine-protein kinase 23.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
Protein: SCAF_ILTVT
Sequence: MSENVDIKYIFVAGYLVVYDHQESAGREYELTREQSKSALPVLPGTIPINIDHESSCVVGTVLTILDLPRGLFCLGVVSTALAPIFLSYVQDDALFANAEEGMVLTETEKFLYLLSNILPSLSLSSRRLEKNEVPGKDFFAHVALCELGRREGTVAIYGATASEAIGAFDDLSAPIKEQLYEIATREKCAEVPRELSRPEITRVLMKKFIHGAFLMDRGTCLKTRREMAAVYNPKYLQANEVITIGIKEHSEETPENAIKDRSVSTQTAPSFDISESQQPSGQTHVPAMESATCSGQFLQTKNGASPSASREDMVYVPFEKYASLLAASARRDNDRRPVSPSREFSRRSRDSTHECSPGRDIWPRGFERHPRLESFMGPGMNHTYRPALYEDPNFCGRFPYIPYQSPASTYPVHPNYYSSNFGQFPGAGTYPIQYPSLHEQTVVSRLDALISALEKNNKRDSEYSENNPRKRSARTISENDPYFPGEMVPAKKITTEQQLCEKKEPVGSGINDILQGILTLQKEVAGLKSASNADSSSERKEELENSNQESARETVDASMPKRLKDAQTKLKRKKEAAAFAQMMAD
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: RL13_SALSV
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: PEPX_STRE4
Sequence: MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKLFFHFQDTDYPLSHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQDFIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKALATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINETANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLNDYFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQIKADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNYLPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSIDFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHVLIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSSENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKGVLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNSNYALTLDLEQSYLLIPTDEEE
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGH_VIBCM
Sequence: MAAMKRLLASSLLILLSGCSLMQPPIESAETIQGTTTVDAVEGDKSESNSGLTDALRNRTDPVAGDPAWAPIHPKGKPEHYAAETGSLFNLASSSSMYDDSKPRGVGDIITVTLNESTKAAKSADADLNKKNDASMDPLAVGGKDLTIGDYNFSYALKNDNKFSGSAAANQSNSMSGSITVEVIEVLANGNLVIRGEKWLTLNTGDEYIRLSGTIRPDDIDFDNTIASNRISNARIQYSGTGTNQDMQEPGFLARFFNVSL
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: SPE1_AVESA
Sequence: MAKNYGDVYHVEGWGEPYFAVNKDGHLCVRIYGRETLPGQEIDVLSVIEQATSADGTGKKLQFPMILRFPDVLRHRINSLHTAFANAIKYTQYGSVYQGVFPVKVNQHKDVVQDMVHFGYDHSYGLEAGSKPELLIAMSCLTKAKPGAYLVCNGYKDSAYVALALAARAMGLNVIIVLEMEEELDIVIEESSKLGVEPVIGVRAKLLTKIPGHFGSTAGKHGKFGLPAEKIYEVAKKLKALNKLHWLKLLHFHVGSMIPTTDIVFKAASEASDIYCALVKEYGVETMTTLDCGGGLGVDYDGTRSGSSDMSVAYGLEEYASSIVQAVRLKCDYHGVPHPVLCTESGRAMASYHSMIILEALSAIPEPKDDEDEATTEQLHGRIRDLSSKLQPTGLSMSSHAVHIKKHGIEMYKLGKKLSKSVTTDAHTIYNYHMNLSVFSLMPDYWGIQHLFPMMPVSRLDEKPTHKATLVDVTCDSDGKVDKFIRDTETMPLHPLDPKLGGYYVAVLLTGAYQEALSNKHNLFGGPSLVRVVGTGNGGAFNVEAALLGSTTEELIGTVSYDVKQDISSVIEERARENKVWEMVEKLVESGLHTMPYLADYKPPPMA
What are the official names of this protein?
Arginine decarboxylase, ADC, ARGDC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: HLDE_PSEAB
Sequence: MKLSMPRFDQAPVLVVGDVMLDRYWHGATSRISPEAPVPVVRVEQHEDRPGGAANVALNIAALGAQALLVGVTGRDEAADSLANSLKAAGVDARFQRIDSQPTIVKLRVMSRHQQLLRVDFEEPFRTDAAALAVDVESLLAKVKVLVLSDYGKGALQNHQVLIQAARARNIPVLADPKGKDFAIYRGASLITPNLSEFETIVGRCADEAELVAKGQELMSELDLGALLVTRGEHGMTLLRHGQPALHLPARAREVFDVTGAGDTVISTLAAALAAGEELPSAVGLANLAAGIVVGKLGTAAISAPELRRAVQREQGSERGVLGLEQLLLAIEDARAHGEKIVFTNGCFDILHAGHVTYLEQARAQGDRLIVGVNDDASVTRLKGVGRPINSVDRRMAVLAGLGAVDWVVSFAEDTPERLLEQVRPDVLVKGGDYGVEQVVGAQIVKAYGGEVRVLGLVENSSTTAIVEKIRQKG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: PXPA_BACC3
Sequence: MTTIDLNCDLGESFGAYKMGNDDEILPFVSSINVACGFHAGDPSVMRQTVEKAMQHNVAIGAHPGFPDLIGFGRRNMNVSANEVYDYVLYQIGALDAFVKAAGGKMQHVKPHGALYNMAATNPEIADAIAKAIHHMNPSLLLYGLANSEAFIQAAEKYNITLVQEAFADRTYKQDGTLTSRTEENALIKNEDEAIKQVLQMVKEGYVNTVNGKKVAVHAQTICLHGDGEKAVQFAEKIYRTFKLNNISICAPK
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: B1R_LOXAS
Sequence: FALAHMVNDLEMVDEFVGKGANGLEIDVTFSSAGQPEYTYHGVPCDCFRNCKRREDFDTYIKYIRHLATPGDPKFRSNLIMLIFDLKLNGLSQDALRSAGKEMADKLVGNYWQDLAEARAYIVLSMPSIEQADFVTAFKDELKDFGYDKNLDRIGYDFSGNEDLGETAKVYEKLNIHEHIWQADGITNCLPRGDSRLKEAISKRDTPGYQYINKVYTWTIDKSGSIANALRLGVDGVMTNYPERVIDALNDSEFSGKLRLATYEDNPWETFKG
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LafSicTox-betaIE1, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YKO2_CAEEL
Sequence: MLNIVLIIGLLAIFNTSSASNDVCHVTRKPLMLPAPGDVYKKAVQFYSNITAPRSTSVLAPVMSSLEVYINTTTTSAFAPAQSIKVADILEEDADAIRVKSIRMAGFIAQCIIFLFVYTIVTMDVEIWKINMDWLKIQYFQHFEDSAAEVPVFKLYMAREIQTCPLPARQNVMIVRQFMEMESNC
What are the official names of this protein?
Uncharacterized protein C05B5.2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS5_LARHH
Sequence: MAKHDIEERGDGLTEKLIGVNRVTKVVKGGRIMAFSALTVVGDGDGGIGMGKGKSKEVPVAVQKAMDQARRSMVKIPLRNGTLQHAVIGKHGATTVFMQPAPEGSGVKAGGAMRQVFDAIGVHNVSAKVHGSTNPYNVVRATLNGLMKINTPADIAAKRGKTVAEILGAE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: RSMG_ALCBS
Sequence: MSLSSTLTQGIDALGLSLSDDQQRLLLAYVDLLVKWNQAYNLTAIRDPQEMVTRHLLDSLAVLAYLEEGDTLDVGTGAGIPGVILAVARPQQAFVLLDSNGKKTRFVRQARRELGLDNVEVVHGRVEQYRKAPSQIICRAFASLSDMLALMTPIMTDNTRLLAMKAASTEEELATLPAQWQGRHHTLTVPGLDEPRTLVVVNKA
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MORN4_MOUSE
Sequence: MTLTKGSFTYSSGEEYRGEWKEGRRHGFGQLVFADGGTYLGHFENGLFNGFGVLTFSDGSRYEGEFSQGKFNGVGVFIRYDNMTFEGEFKNGRVDGFGLLTFPDGSHGIPRNEGLFENNKLLRREKCSAVVQRAQSASKSARNLTA
What is the function of this protein?
Plays a role in promoting axonal degeneration following neuronal injury by toxic insult or trauma.
What are the official names of this protein?
MORN repeat-containing protein 4.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, filopodium tip. Cell projection, stereocilium. Note=Found in the cytoplasm in the absence of MYO3A and localizes at filopodial tips in the presence of MYO3A.
Protein: MIAB_THEFY
Sequence: MSQSRTYQVRTYGCQMNVHDSERLSGLLEAAGYQRAAEGTTPDVVVFNTCAVRENADNRLYGNLGQLRPVKDANPDMQIAVGGCLAQKDRGEIIRRAPWVDVVFGTHNIGSLPALLERARVQREAQVEIVESLERFPSTLPTRRESVYAAWVAISVGCNNTCTFCIVPALRGKEKDRRPGDILAEIRAVVAEGAIEVTLLGQNVNAYGSEFGDRQAFSKLLRACGEIEGLERVRFTSPHPRDFTDDVIAAMAETPNVMPQLHMPLQSGSDRILRAMRRSYRAERFLRIVEKVREAIPDAAITTDVIVGFPGETEEDFAETLRVMEEVRFAHAFTFQYSKRPGTPAASMDNQVPREVVKERYQRLLELQERISEEENAKFVGREVEVLVAEGEGRKDDVHRRMSGRARDNRLVHFAVDEGVTVRPGDMVTVEVTYAAPHHLVADSGIRNLRRTRAGDAWEARNAPERRPTGVLLGMPKVGAPEPQPSVVGGCCDS
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA2_CLOB1
Sequence: MSKGIVALAMSGGVDSSVSAYILKERGYDVIGIYMDLWRDERKGYCNKSAAEDARRVAEKLDIPFHVINIEKKFKDNVIDYFIDEYLSGRTPNPCVACNKTIKFEAFFNAAKEFGADFMATGHYCKIEERNGRKVIVKAEDDKKDQTYMMYNLKQYQLERTIMPCGEYKKDHIREIAENIGLDVYNKKDSQEICFIPDNDHGGFIKRNYKSKIKQGNFVDKAGKIIGKHKGIIYYTIGQRKGLGIALGKPAYVIDINPITNEVVIGDEEDIFRTELIAKDVNFIPFDKLEKSMELEAKVRYSAKPSKATIIPLENNKVKVVFQNKQRAITKGQSVVFYDKDMLVGGGIIEEIV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 2.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPC3_RAT
Sequence: MAGTVRTACLLVAMLLGLGCLGQAQPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQMMNPGLPESVLDINECLRGARRDLKVFGSFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKVLKVARVEHEETLSSRRRELIQKLKSFISFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVVDKSLDEEGLESGDCGDDEDECIGSSGDGMMKVKNQLRFLAELAYDLDVDDAPGNKQHGNQKDNEITTSHSVGNMPSPLKILISVAIYVACFFSWCTDLPCPCLCCPAAPCGPPT
What is the function of this protein?
Cell surface proteoglycan (By similarity).  Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins (By similarity).  Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation (By similarity).  Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands (By similarity).  Positively regulates the non-canonical Wnt signaling pathway (By similarity).  Binds to CD81 which decreases the availability of free CD81 for binding to the transcriptional repressor HHEX, resulting in nuclear translocation of HHEX and transcriptional repression (By similarity).  Inhibits the dipeptidyl peptidase activity of DPP4 (By similarity).  Plays a role in limb patterning and skeletal development by controlling the cellular response to BMP4 (By similarity).  Modulates the effects of growth factors BMP2, BMP7 and FGF7 on renal branching morphogenesis (By similarity).  Required for coronary vascular development (By similarity).  Plays a role in regulating cell movements during gastrulation (By similarity).
What are the official names of this protein?
Glypican-3, Intestinal protein OCI-5.
What is the protein family that this protein belongs to?
Belongs to the glypican family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Protein: GPDA_ENT38
Sequence: MSTVNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPKHIATLQHDRCNVAFLPDVPFPDSLHLESDLATALAASRNILVVVPSHVFGQVLHQIKPLMRADARIVWATKGLEAETGRLLQDVAREVLGDDIPLAVISGPTFAKELAAGLPTAISLASTDQTFSDDLQHLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGEALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVMGAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRSRKEERSSS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GEX1_YEAST
Sequence: MSSSVVGASSNKKSGIRQSCEIIERERHSNDDTYSMTSTFFKLKENEIMSAQFDSLKYKILLISTAFVCGFGISLDYTLRSTYTGYATNSYSEHSLLSTVQVINAVVSVGSQVVYSRLSDHFGRLRLFLVATIFYIMGTIIQSQATRLTMYAAGSVFYNCGYVGTNLLLTLILSDFSSLKWRMFYQYASYWPYIIIPWISGNIITAANPQKNWSWNIAMWAFIYPLSALPIIFLILYMKYKSSKTAEWRSLKEQARKERTGGLFENLVFLFWKLDIVGILLITVSLGCILVPLTLANETSQKWHNSKIIATLVSGGCLFFIFLYWEAKFAKSPLLPFKLLSDRGIWAPLGVTFFNFFTFFISCDYLYPVLLVSMKESSTSAARIVNLPDFVAATASPFYSLLVAKTRKLKLSVIGGCAAWMVCMGLFYKYRGGSGSHEGVIAASVIMGLSGLLCSNSVIVILQAMTTHSRMAVITGIQYTFSKLGAAIGASVSGAIWTQTMPNQLYKNLGNDTLAEIAYASPYTFISDYPWGSPERDAVVESYRYVQRIIMTVGLACTVPFFAFTMFMRDPELIDKATHEEFTEDGLVVLPDEENIFSQIKALFRHNRSNKKLGC
What is the function of this protein?
Proton/glutathione antiporter that imports glutathione from the vacuole and exports it through the plasma membrane.  Involved in resistance to oxidative stress and modulation of the PKA pathway.
What are the official names of this protein?
Glutathione exchanger 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: YJKA_BACSU
Sequence: MDYLSLSLTMIFVLIALFLSKSFKAGVEKDMIIATIRAAVQLLIIGYVLSLIFRGDHPVFILLMVLLMLAVAAQNVIKRKKNTIGSFWRVFAALAIVEIVTQGILLSLHIIPLTARYVIPISGMVIGNSMVLSSLFLNRLNSEVGVRKEEIQLILSLGGTPKQSIQRILTSAMKMSMIPTLESQKTLGLVQLPGMMTGQILAGADPIQAVRFQLLIVFTTMASAALTCVILSVLTYPSLFTVHQQLKQNE
What are the official names of this protein?
UPF0014 membrane protein YjkA.
What is the protein family that this protein belongs to?
Belongs to the UPF0014 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.