PharMolix/UniProtQA huggingface dataset:
Protein: IXTPA_BIFLS
Sequence: MQIVVATHNEGKLVEIRRILEEDLGVDAENIELVSAGSLHLPDPVETGVTFQENALLKARAVAIRTGLPAVADDSGLIVDVMGNAPGILSARWAGAHGHDKANNALLLAQIGDIPDDKRTARFRCAAALVVPDTEAGADVTGGVAADGITVHTTAADGSTAPVHARYAIKSETVELGDMPGRIIREARGEHGFGYDPLFVPDDQPAGRVSTEPDHEGEPLTSAEMTSAEKNAISHRGKALKALVPAIEALLH
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: CLPP_SYNWW
Sequence: MSYLVPMVVEQTNRGERSYDIYSRLLKDRIIFLGSGIDDTVANLVIAQLLFLEAEDPDKDISLYINSPGGSITAGMAIYDTLQYIRPDVSTICVGLAASMGAFLLAAGKKGKRYALPNAEIMIHQPAGGTQGQATDIEIHARRIMNMKESLNKILAERTGQPLERIQKDTDRDYFMTAQEAKEYGIIDEVISHPKKTSKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYOZ2_PONAB
Sequence: MLSHNTMVKQRKQQATAIMKEVHGNDVDGMDLGKKVSIPRDIMLEELSHLSNRGARLFKMRQRRSDKYTFENFQYQSRAQINHSIAMQNGKVDGSNLEGGSQQAPLTPPNTPDPRSPPNPDNIAPGYSGPLKEIPPEKFNTTAVPKYYQSPWEQAISNDPELLEALYPKLFKPEGKAELPDYRSFNRVATPFGGFEKASRMVKFKVPDFELLLLTDPRFMSFVNPLSGRRSFNRTPKGWISENIPIVITTEPTDDTTVPESEDL
What is the function of this protein?
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere.  Plays an important role in the modulation of calcineurin signaling.  May play a role in myofibrillogenesis (By similarity).
What are the official names of this protein?
Myozenin-2, Calsarcin-1.
What is the protein family that this protein belongs to?
Belongs to the myozenin family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle.
Protein: RAPA_VIBPA
Sequence: MTFALGQRWISDTESDLGLGTVVAMDARTVTLMFAASEENRVYARNDAPVTRVTFNVGDVIDCQEGWSLKVEEVLEDEGLYTYFGTREDTQETAVVLREIFLSNQIRFNKPQDKLYAGQIDRMDNFVLRYRALTNQFEQHKSPMRGLCGMRAGLIPHQLYIAHEVGRRHAPRVLLADEVGLGKTIEAGMIIHQQVLSGRAERILIVVPETLQHQWLVEMMRRFNLHFSIFDEERCIEAFADAENPFDTQQYVLCSLDFLRKSRKRFEQALEGEWDLLVVDEAHHLEWSQDKPSREYQVVEGLAERTPGVLLLTATPEQLGRESHFARLRLLDPDRFYDYEAFVEEEEQYAPVADAITSLFSGEKLPDEAKNQITELLSEQDVEPLFRIIESNSDEEAKASARQELIDNLMDRHGTGRVLFRNTRAAIKGFPTRNVHLMPMDIPQQYTTSMRVAGMIGGKMSSEARAMKNLYPEEIFQEFEGDDASWWQFDSRVNWLLEKVKEKRGEKILVIASRASTALQLEQALREREGIRATVFHEGMSILERDKAAAYFAQEEGGAQVLICSEIGSEGRNFQFANQLVMFDLPFNPDLLEQRIGRLDRIGQNRDIDIHVPYLKGTSQAILARWFDEGLNAFAETCPTGRAVYDKYSDALIEILASGDTSTLDEIIEESAKLNKELKSQLEQGRDRLLEMHSNGGEKAQQIVEKIESTDGDTNLVTFALSLFDTIGLNQDDKGENALVVTPSEHMMVPSYPGLPYEGATITFDRDTALSREDMHFISWEHPMIQGGIDLLMSEGVGTSAVSLLKNKALPVGTILLELIYAVDAQAPKRSGITRFLPKTPIRLMMDSRGNDLSAQVEFEGFNRQLSPVNRHLGSKLVTSVQKDVHRLIEAGDVLVEEKVEAVRKQAQQDMQQSLNTELERLQALKAVNPNIRDEEIEAIEAQIKELTGYINQAQVQLDSLRLIVVSHN
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: RS9_BACVZ
Sequence: MAQVQYYGTGRRKSSVARVRLVPGEGRIVVNNREISEHIPSPALIEDIKQPLTLTETAGTYDVLVNVHGGGLSGQAGAIRHGIARALLEADPEYRATLKRAGLLTRDARMKERKKYGLKGARRAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ENTS_SHIBS
Sequence: MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWLVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAEIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRRFRQTPPQVTASDS
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RK23_CITSI
Sequence: MDGIKYAVFTDKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHQLPRKGRRMGPIMAHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: HIS6_YERPN
Sequence: MLAKRIIPCLDVKDGQVVKGVQFRNHEIIGDIVPLAQRYAQEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIKSVEDASQILTFGADKISINSPALADPTLITRLADRYGVQCIVVGIDTWYDTESDSYQVYQFTGDEKRTKATTWQTEDWVKEVQLRGAGEIVLNMMNQDGVRNGYDLRQLQQMRAICHVPLIASGGAGTPDHFLEAFRDADVDGALAASVFHKQIINIGELKKYLSEQGVEIRVC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_STAA1
Sequence: MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNGQLVDLTKPLETDGSIGIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEGGFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKLELIDAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIYGTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRREIERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPMNCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRPDQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEAADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDGEHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQDELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQETVEKDEFIWNLVDEIRLKKHR
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HCAD_ECO7I
Sequence: MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDEQHLPYERPPLSKSMLLEDSPQLQSVLPAHWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWDQLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELAASATQRGCKATVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGENVELTLQSGETLRADVVIYGIGISANDQLAREANLDTANGIVIDEACRTCDPAIFAGGDVAITRLDNGALHRCESWENANNQAQIAASAMLGLPLPRLPPPWFWSDQYSDNLQFIGDMRGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRLIRKWIQSGKTFDAKLLTDEHIALKSL
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase ferredoxin--NAD(+) reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: ATPL_ECOLI
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of 10 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, Dicyclohexylcarbodiimide-binding protein, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GAG_SCVLB
Sequence: MSSLLNSLLPEYFKPKTNLNINSSRVQYGFNARIDMQYEDDSGTRKGSRPNAFMSNTVAFIGNYEGIIVDDIPILDGLRADIFDTHGDLDMGLVEDALSKSTMIRRNVPTYTAYASELLYKRNLTSLFYNMLRLYYIKKWGSIKYEKDAIFYDNGHACLLNRQLFPKSRDASLESSLSLPEAEIAMLDPGLEFPEEDVPAILWHGRVSSRATCILGQACSEFAPLAPFSIAHYSPQLTRKLFVNAPAGIEPSSGRYTHEDVKDAITILVSANQAYTDFEAAYLMLAQTLVSPVPRTAEASAWFINAGMVNMPTLSCANGYYPALTNVNPYHRLDTWKDTLNHWVAYPDMLFYHSVAMIESCYVELGNVARVSDSDAINKYTFTELSVQGRPVMNRGIIVDLTLVAMRTGREISLPYPVSCGLTRTDALLQGTEIHVPVVVKDIDMPQYYNAIDKDVIEGQETVIKVKQLPPAMYPIYTYGINTTEFYSDHFEDQVQVEMAPIDNGKAVFNDARKFSKFMSIMRMMGNDVTATDLVTGRKVSNWADNSSGRFLYTDVKYEGQTAFLVDMDTVKARDHCWVSIVDPNGTMNLSYKMTNFRAAMFSRNKPLYMTGGSVRTIATGNYRDAAERLRAMDETLRLKPFKITEKLDFRVAAYAIPSLSGSNMPSLHHQEQLQISEVDAEPINPIGEDELPPDIE
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=2 symmetry, about 40 nm in diameter, and consisting of 60 capsid proteins asymmetric dimers.  The capsid encapsulates the genomic dsRNA and the polymerase and remains intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of the virion and are extruded into the cytoplasm (By similarity).
What are the official names of this protein?
Major capsid protein, Gag protein, Major coat protein.
What is the protein family that this protein belongs to?
Belongs to the totivirus major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: SAHH_PROM4
Sequence: MLAASASTQQLHNHIEYEIADIELAEFGRKELAIAEKEMPGLMALREKYHKEKPLKGARIAGSLHMTIQTAVLIETLVALGAQVRWASCNIFSTQDHAAAAIASSGIPVFAKKGETLDEYWAYTHRILEWGDQETPNMILDDGGDATGLVILGSKAEQDLSVLERPNNEEEIALYSSIRNKLSDDPSFYSRIKSSIQGVTEETTTGVARLYQMQANGSLPFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMVAGKIALVIGYGDVGKGSAQSLRGLGATVMIAEIDPICALQASMEGYRVVRLNDVVQNVDIFVTATGNFNVITHDHLIRMKDEAIVCNIGHFDNEIDVASLKPYQWENIKPQVDHITLPSGNKIILLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQIELFTQGSNYDNQVYILPKHLDELVARLHLDKIGANLTELTEEQAAYINVPIKGPYKSEQYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_CORA7
Sequence: MSAICQVTGRKPEFGKQVSHSHRRTSRRWNPNVQRRRYYLPSEGRTITLTVSTKGMKIIDRDGIESVVAKIRARGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CYSC_SALNS
Sequence: MALHDENVVWHSHPVTVAAREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALHQRGVSTYLLDGDNVRHGLCRDLGFSDADRQENIRRVGEVASLMADAGLIVLTAFISPHRAERQLVKERVGHDRFIEIYVNTPLAICEQRDPKGLYKKARAGELRNFTGIDAIYEAPDSPQVHLNGEQLVTNLVSQLLDLLRRRDIIRS
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: PURA_CROS8
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRDNVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDVAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKATFAEKLKEVLEYHNFQLVNFYKVEAVDYQKVLDDVMAIADVLTSMVVDVSDLLDQARKRGDFIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGIGPRYVDYVLGIIKAYSTRVGAGPFPTELFDDIGEFLCKKGNEFGATTGRRRRTGWLDAVAVRRAVQINSLSGFCLTKLDVLDGLEEVKICVAYRMPDGREVTTTPMAADDWEGIEPIYETMPGWSESTFGVKERSGLPQAALNYIKRIEEVTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISY1_NEPRA
Sequence: MSWWWAGAIGAAKKRIDEDEAPRNYESVALIVGVTGIVGNSLAEILPLSDTPCGPWKVYGVARRPRPSWNEDHPITYISCDVLDSVDVEAKLSPLTDVTHIFYATWTKRSTEKENCEANGKMLKNVLNAMIPNCPNLKHICLQTGRKHYLGAFEDWKIKRHDPPLTEDLPRLDSQNFYYTQEDILFEEVQKKESLTWSVHRPGTIFGFSPYSMMNLVGTLCVYAAICKHEGAVLRFPGCKGAWDGYSDCSDADLIAEHQIWAAVDPYAKNEAFNVSNGDVFKWKHFWKVLAEQFGVECGEYEEGKEVKLQDLMKDKGPVWDKIVRENGLSTTKLEDVGNWWFSDIVLGNECWLDTMNKSKEHGFLGFRNSKNSFISWIDKVKAFKIVP
What is the function of this protein?
Iridoid synthase that catalyzes the first step in generation of the iridoid ring scaffold using the linear monoterpene (6E)-8-oxogeranial as substrate (PubMed:29091815).  Iridoids comprise a large family of distinctive bicyclic monoterpenes that possess a wide range of pharmacological activities, including anticancer, anti-inflammatory, antifungal and antibacterial activities (Probable).  Catalyzes the conversion of the linear monoterpene (6E)-8-oxogeranial to (S)-8-oxocitronellyl enol, a precursor of nepetalactones, which are metabolites that are both insect-repellent and have euphoric effect in cats (PubMed:29091815).
What are the official names of this protein?
(S)-8-oxocitronellyl enol synthase ISY1, Iridoid synthase 1, NmISY1.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: G6PI_ENTFA
Sequence: MSHIQLDYSKLAPFVADHELEYMQTQVTAVDKALREGTGAGNDFTGWIDLPENYDKEEFARIKKAAAKIQSDSEVLVVIGIGGSYLGARAAIEFLTHSFNNLLSKEERKAPQIFFAGNSISSTYLADLINVIGDRDFSVNVISKSGTTTEPAIAFRVFKELLINKYGKEEANKRIYATTDRAKGAVKVEADAEGWETFVIPDDVGGRFTVLTPVGLLPIAVSGADIDRLMEGANDARKEYGATSDLKENQAYQYAALRNILYRKGKTTEMLINYEPGMHYFSEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYVQEGMRNLFETVVKIENPRHSISIPEQNEDLDGLGYLQGKEIDFVNTKAFEGTLLAHTDGGVPNMIVKVPTMDAYSLGYVMYFFEIAVGISGYLNGVNPFDQPGVEAYKRNMFALLGKPGFEELAKDLNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SC18_MESMA
Sequence: VRDAYIAEDYDCVYHCARDA
What is the function of this protein?
Binds to sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin BmK 18(2).
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: U92A1_ARATH
Sequence: MAEAKPRNLRIVMFPFMGQGHIIPFVALALRLEKIMIMNRANKTTISMINTPSNIPKIRSNLPPESSISLIELPFNSSDHGLPHDGENFDSLPYSLVISLLEASRSLREPFRDFMTKILKEEGQSSVIVIGDFFLGWIGKVCKEVGVYSVIFSASGAFGLGCYRSIWLNLPHKETKQDQFLLDDFPEAGEIEKTQLNSFMLEADGTDDWSVFMKKIIPGWSDFDGFLFNTVAEIDQMGLSYFRRITGVPVWPVGPVLKSPDKKVGSRSTEEAVKSWLDSKPDHSVVYVCFGSMNSILQTHMLELAMALESSEKNFIWVVRPPIGVEVKSEFDVKGYLPEGFEERITRSERGLLVKKWAPQVDILSHKATCVFLSHCGWNSILESLSHGVPLLGWPMAAEQFFNSILMEKHIGVSVEVARGKRCEIKCDDIVSKIKLVMEETEVGKEIRKKAREVKELVRRAMVDGVKGSSVIGLEEFLDQAMVKKVEN
What are the official names of this protein?
UDP-glycosyltransferase 92A1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: VTS1_CANGA
Sequence: MLANKFDEMHHPVPDSSMNGNPLCNSSANVGQGNRNSNPIQSRGTGHSSSPIYNNPLRTAHPGAVLLSPQSSSLNIIDTTVGNAMSPTVPSSAASSIFFNDFGLDSSTNLNKSAMNANSNRPMTTIPLSSNSTSQSYTLSFQQENKKTNSNSTLNNVNNGLVTAGSVSNSHNNIFLDSFLSHDNTMQPNNSSNNNNNNNQNANNSLNFNTDVNQLCTWMSMLTANQQSVVMDNIISVLNESTLNYTKMKLDTMFGTTSSSPTSAEAMQNLGQPKESGNQNSNQNNIASPIPSTLDSVFANNSMKYLQSQSTSGSNHFHQAFNSKGSSMNWSSQASNIQNPAYDYLNDYRQRPKSAEPPLSHQTHYQPSNLSISQFKPQNSNGNSSNTNTNRNLNNSNNSNNNSTANNNNIGSNNTKRMNDITNSADVPVTSSFQNLTLNNQNGSTTTSSNNGNSSSGASSNSSMNPKSLTDPKLLNNIPIWLKTLRLHKYSDILNDLSWEKLIYLEDEDLLKRGVLALGARRKLLKAFTIVRDYKNRDLIDNSAYLNIK
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
What are the official names of this protein?
RNA-binding protein VTS1.
What is the protein family that this protein belongs to?
Belongs to the VTS1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, P-body.
Protein: FOLD_STRPB
Sequence: MTELIDGKALAQKMQQELAAKVNNLKQKKGIVPGLAVILVGDDPASQVYVRNKERAALTVGFKSETVRLSEFICQEELIAVIERYNADNTIHGILVQLPLPNHINDKKIILAIDPKKDVDGFHPMNTGHLWSGRPLMVPCTPSGIMELLREYNVNLEGKHAVIIGRSNIVGKPMAQLLLDKNATVTLTHSRTRQLEEVCRCADVLIVAIGQGHFITKQYIKEGAIVIDVGMNRDDNGKLIGDVAFDEVAEVAAKITPVPGGVGPMTIAMLLEQTYQSALRSTHK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: SMG9_RAT
Sequence: MSESGHSQPGLYGIERRRRWKEPGSSGPQNLSGPGGRERDYIAPWERERRDGSEDPSTNVMQKTPIILSKPPAERSKQPPPSTAPAAPPAPAPLEKPIVLMKPREEGKGPVAATGASTPEGTAPPPPTAPAPPKGEKEGQRPTQPVYQIQNRGMGTAAPTAMDPVVGQAKLLPPERMKHSIKLVDDQMNWCDSAIEYLLDQTDVLVVGVLGLQGTGKSMVMSLLSANTPEEDQRAYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSAAGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHLMIDQLMAHSHLRYKGTLSMLQCNIFPGLPPDFLDAEVNLFLVPFMDSEAENENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMSMARPQLSHTILTEKNWFHYAARIWDGVKKSSALAEYSRLLA
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.  Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (By similarity).  Plays a role in brain, heart, and eye development.
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG9.
What is the protein family that this protein belongs to?
Belongs to the SMG9 family.
Protein: SERC_THASE
Sequence: MRTSSMMKRMAAMSLAAAAAWATGAAAAADGAPAAQRTIQVLSVKGGDAASPQAAVWKKAPTGQVALQTAFPGHASIVGTALTQQMTAQAVRAGDRLFVRLAWRDATANTEIKDTDQFVDGAAVQFPVNGKDTTLAFMGDPDNPVNVWHWRADGRTRNLVAKGFGTATPVPAEGLRSTATRTRDGWEVVISRPLRVKAEEGADLQGRRTMPIAFAAWDGENQERDGLKAVTMEWWQLNF
What is the function of this protein?
May transfer electrons to the iron-sulfur centers of SerB.
What are the official names of this protein?
Selenate reductase subunit gamma, Selenate reductase heme subunit.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL24_HELAH
Sequence: MKSEIKKNDMVKVIAGDDKGKVAKVLAVLPKTSQVIVEGCKVVKKAIKPTDDNPKGGFIHKEKPMHISNVKKA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: X_WHV4
Sequence: MAARLCCQLDSARDVLLLRPFGPQSSGPSFPRPAAGSAASSASSPSPSDESDLPLGRLPACFASASGPCCLVFTCAELRTMDSTVNFVSWHANRQLGMPSKDLWTPYIKDQLLTKWEEGSIDPRLSIFVLGGCRHKCMRLL
What is the function of this protein?
Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription.  Does not seem to be essential for HBV infection.  May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma).  Most of cytosolic activities involve modulation of cytosolic calcium.  The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted.  May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential.  May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC).  Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation.  This host complex would otherwise bind to viral episomal DNA, and prevents its transcription.  Moderately stimulates transcription of many different viral and cellular transcription elements.  Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT.
What are the official names of this protein?
Protein X, HBx, Peptide X, pX.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus protein X family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Host mitochondrion. Note=Mainly cytoplasmic as only a fraction is detected in the nucleus. In cytoplasm, a minor fraction associates with mitochondria or proteasomes.
Protein: Y2281_SULIL
Sequence: MKITPIAFESLGVRSQATLIETKDLRVLVDPAISLAPRRYNLPPHQREVDRLTELAKVLVDVAKDVDVIIVSHYHYDHHDPGYVIPTDIYKNKLVFIKDPQNMINNSQKYRRAPRFLRSIKDKPSKIEIADGKTLELGHTTISFSPAVPHGADERLGYVIQVAISDKDSTVIFTSDIEGAPKDVHLKFTKEKMPKTIIIDGPLSYLLGRVLKEEELEKSIRNMEEIVKNGLETVIIDHHVLRDINYAEVLKPVYDIAKDLGVRVTTAAEYLNLEPLILEARRKELFKEDNRPARIPRGLANLLSAGEG
What are the official names of this protein?
UPF0282 protein LS215_2281.
What is the protein family that this protein belongs to?
Belongs to the UPF0282 family.