PharMolix/UniProtQA huggingface dataset:
Protein: AMP1_STEME
Sequence: MLNMKSFALVMLFATLVGVTIASGPNGQCGPGWGGCRGGLCCSQYGYCGSGPKYCAHNTPLSEIEPTDAGRCSGRGTCSGGRCCSKYGYCGTGPAYCGLGMCQGSCLPDMPNHPAQIQARTEAAQAEAQAEAYNQANEAAQVEAYYQATQAQTQAQPQVEPAVTKAP
What is the function of this protein?
Antimicrobial peptide active against the fungus A. alternata (IC(50)=8. 6 uM) and the oomycetes P. infestans OSV 12 (IC(50)=11 uM) and P. infestans PRILL 2 (IC(50)=6. 5 uM).
What are the official names of this protein?
Antimicrobial peptide 1, SmAMP1.
Protein: GLND_MYCTU
Sequence: MEAESPCAASDLAVARRELLSGNHRELDPVGLRQTWLDLHESWLIDKADEIGIADASGFAIVGVGGLGRRELLPYSDLDVLLLHDGKPADILRPVADRLWYPLWDANIRLDHSVRTVSEALTIANSDLMAALGMLEARHIAGDQQLSFALIDGVRRQWRNGIRSRMGELVEMTYARWRRCGRIAQRAEPDLKLGRGGLRDVQLLDALALAQLIDRHGIGHTDLPAGSLDGAYRTLLDVRTELHRVSGRGRDHLLAQFADEISAALGFGDRFDLARTLSSAGRTIGYHAEAGLRTAANALPRRGISALVRRPKRRPLDEGVVEYAGEIVLARDAEPEHDPGLVLRVAAASADTGLPIGAATLSRLAASVPDLPTPWPQEALDDLLVVLSAGPTTVATIEALDRTGLWGRLLPEWEPIRDLPPRDVAHKWTVDRHVVETAVHAAPLATRVARPDLLALGALLHDIGKGRGTDHSVLGAELVIPVCTRLGLSPPDVRTLSKLVRHHLLLPITATRRDLNDPKTIEAVSEALGGDPQLLEVLHALSEADSKATGPGVWSDWKASLVDDLVRRCRMVMAGESLPQAEPTAPHYLSLAADHGVHVEISPRDGERIDAVIVAPDERGLVSKAAAVLALNSLRVHSASVNVHQGVAITEFVVSPLFGSPPAAELVRQQFVGALNGDVDVLGMLQKRDSDAASLVSARAGDVQAGVPVTRTAAPPRILWLDTAAPAKLILEVRAMDRAGLLALLAGALEGAGAGIVWAKVNTFGSTAADVFCVTVPAELDARAAVEQHLLEVLGASVDVVVDEPVGD
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory protein (GlnB), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII protein and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII protein, and plays an important role in the regulation of nitrogen assimilation and metabolism (Probable).
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: RL14_STRPS
Sequence: MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVKQATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPVARELREGGFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FDB29_GIBM7
Sequence: MTTKTSNETYGAGTVVDSEFSPLPAECERILRIFAARTPGFTKDEALLSGVNFHGDDLPCIPGPIKSQAVTAVLHAMVGIVGLEILHLRGVTTDNQIDIDVNHAGLYPATAALVDIDGVTGPEVIKLPTVPQWDKDRASNSPLVYRATAIYETADSGVWFQLHGSLDSWKVLALLGIGKDLDSEIRTNDAAYELIQERVRKYRAREIEQLVVEKGLSGSIVYSPEEWRQTEMGRSLSRHPLVNYKQKSHCATLAPASFPVLEDKRPLAGIKVVELTRIIAGAAAGAALASLGAEVIRVNSSKLKDYTPAQPSSLMAGKKTIDLDLEDPADHKKLMQLFEQADVILQGYRLGSLARRGFGLEAALELANKRGRGVVYVDENCYGPDGYYAERPGWQQVADAAAGSSYVMGQSFGFPKGQGVLPSLPISDMSTGILTALTIMCGIRDRAKFGGSYHGHASLTAYNMATLDSEVRLYQREVVQKISDKYEFPTWSSDVHVAPLYYSILDAWGKKSELIKDEKHYIHFSDSVFGSDLRVLGPVVRYDKEEYSPKWNSPPVPFCHHEFTMFSNQ
What is the function of this protein?
Acyl-CoA transferase; part of the Fusarium detoxification of benzoxazolinone cluster 2 (FDB2) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the FDB1 cluster gamma-lactamase MBL1 to aminophenols (PubMed:26808652, PubMed:12788712).  MBL1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26808652, PubMed:12788712).  The FDB2 cluster N-malonyltransferase FDB2/NAT1 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:19302487, PubMed:12788712).  FDB2/NAT1 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:19302487, PubMed:12788712).  The duplicated dienlactone hydrolases DLH1 and DLH2 may provide redundant function for hydrolyzing the lactone moiety in the BOA molecule (Probable).  The roles of the amidases an other enzymes encoded by the 2 FDB clusters have not been identified so far (Probable).
What are the official names of this protein?
Acyl-CoA transferase FVEG_12629, Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12629, FDB2 cluster protein FVEG_12629.
What is the protein family that this protein belongs to?
Belongs to the CoA-transferase III family.
Protein: SMXL2_ARATH
Sequence: MRADLITIQQTLTPEAATVLNQSIAEATRRNHGHTTPLHVAATLLSSSSGYLRQACIKSHPNSSHPLQCRALELCFSVALERLPTTSTTTTTTSSSSSSSPSQTQEPLLSNALTAALKRAQAHQRRGCPEQQQQPLLAVKVELEQLIISILDDPSVSRVMREASFSSPAVKSAIEQSLIGNSVSNSRQTGSPGIINPSAIGFGYRSVPAPVNRNLYLNPRLQQPGVGMQSGMMIQRTDEAKRVIEIMIRTRKRNPVLVGDSEPHILVKEILEKIENGEFSDGALRNFQVIRLEKELVSQLATRLGEISGLVETRIGGGGVVLDLGDLKWLVEHPAANGGAVVEMRKLLERYKGRLCFIGTATCETYLRCQVYYPSMENDWDLQAIPIAAKSSLPAIFPRLGSNNNNNAMLLSNNIISIESISPTRSFQIPMSKMSCCSRCLQSYENDVAKVEKDLTGDNRSVLPQWLQNAKANDDGDKKLTKDQQIVELQKKWNDLCLRLHPNQSVSERIAPSTLSMMKINTRSDITPPGSPVGTDLVLGRPNRGLSSPEKKTREARFGKLGDSFDIDLFKKLLKGLAKSVWWQHDAASSVAAAITECKHGNGKSKGDIWLMFTGPDRAGKSKMASALSDLVSGSQPITISLGSSSRMDDGLNIRGKTALDRFAEAVRRNPFAVIVLEDIDEADILLRNNVKIAIERGRICDSYGREVSLGNVIIILTANSSLGSAKNVASIDETRLESLVNKGWELRLSVCNSSKTRKRKPNWLYSDNDQTKQRKEICFDLNEAAEFDSSSDVTVEHDQEDNGNLVHKLVGLVDDAILFRPVDFDSIKSKTAESLKKRFSNGLADGLTVEIEDDALERIAGAIWLSKISLEEWLEEAMGSSLNSVKSRVSSSEDSVIRIELEDDLNDRISGGYLPSSIRTVVV
What is the function of this protein?
Probable component of a transcriptional corepressor complex that acts specifically in the karrikin pathway (PubMed:26754282).  Controls seedling growth redundantly with SMAX1, but is not involved in leaf morphology, shoot branching or germination control (PubMed:26754282).
What are the official names of this protein?
Protein SMAX1-LIKE 2, AtSMXL2.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
Protein: RL17_BUCBP
Sequence: MRHRKIGRRFNKSATHVKAMLKNMVCSLFRYEMIKTTVSKAKELRRVAEPLITCAKIDSVANRRLVFSRIRDNKIVFKLFRDLGPHFLGQFGGYTRILRCGFRSGDQAPMAYIQLINRVKNKKELVYKK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: LGT_PSEMY
Sequence: MLPYPQIDPVAIALGPLKIHWYGLMYLVGIGGAWWLASRRLARFDASWSKEKLSDLVFWVAMGVILGGRLGYVFFYDFAAYIAEPAKILRVWEGGMSFHGGLIGVMLATWWFGKRNGKSFFELMDFIAPLVPIGLGAGRIGNFINAELWGKATDVPWAMVFPTDPEQLARHPSQLYQFALEGVALFTILWFYSRKPRPTMAVSGMFAACYGVFRFIVEFVRVPDAQLGYLAWGWLTMGQILCLPMILGGIGLIAYAYKRQPVQGAA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CBPC2_XENTR
Sequence: MCPALSTDLKQEVLTDPYESFMHHHLQYYGYFRGLEPREQFKLPVQRCRKVVTDSDSDMPSSQEDQKKLVYSLLLDSPVFKSRQLVFEDQEGKIIPRLREPKDLYGSSSQDGCWQQARWPSECEVIKQDISHIEWDPTDREIFYKPTGNEPKPPVVSEGTGAVVYEISPAHKGSYFKGSRTGGRKCSHRKNQKVQCNNDLQFESRFESGNLQKAMKVGMYEYELTLRTDLYTSKHTQWFYFQVKNTRKGVPYRFTITNLMKTNSLYNEGLKPLLYSQQDAALKGIGWRREGKDIKYYKNTRSLDGRSLYSLTWTFEFPHDDDICYFAHCYPYTYSDLQRDLKSKISDPACSHYCKLRTLCRSLAGNSIYLLTITSPSTNLTTGAKKKAIVVTARVHPGETNGSWMMKGFLDFILSDSPDAQLLRDTFIFKVVPMLNPDGVIVGNYRCSLSGRDLNRNYKSMLKDAFPCIWHTRSMVKRLLTEREVILYCDFHGHSRKNNVFMYGCNSKGHPLTKLHERIFPLMLSKNAPDKFLFKGCKFKVQKSKEGTGRIDMWKQGIQNSYTMEATFGGSTLGNRKDTHFTTQDLKSMGHHFCDTLLDYCDPDSSKFKLCLSELQRLVEEDIREKMKQLGRDMDSDFTLSDITLSDLESSTSGSNSSESDGLPAHLVDIAEKFYQKKKRRLRSRKERNSLYQKRNARQKQKLHEAVEVSEPAAHIVRNELTKSSGKRKKEQKVAKIKFQEDLVPQTEENLTTAAPTEKSSMLYSRKPESVSMKTQMINSLPTSCVRDFMDLDHVCERQMTIRPRPSANGNRLPLIITVVQQSTLPPVPKGISALKQHPPPFHSILDQSGDQLTVADHVFRRDKSVAKRGFSSAGIRPYCSGISGEKQKVLDGSIVPLDLHLSLSPEVHRQNKPRQEPLITLGSTEYFEGFLPKPKTDPVRRFPGISSSEPHFPNSSEDITVRNTMK
What is the function of this protein?
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins.  Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein.  Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate.  Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins.
What are the official names of this protein?
Cytosolic carboxypeptidase 2, ATP/GTP-binding protein-like 2, Protein deglutamylase CCP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Colocalizes with gamma- tubulin in the centrioles and with glutamylated tubulin in the basal bodies of ciliated cells.
Protein: RR12_CHLSC
Sequence: MPTIKQLIRNTRQPIRNVTKSPALRGCPQRRGTCTRVYTITPKKPNSALRKVARVRLTSGFEITAYIPGIGHNSQEHSVVLVRGGRVKDLPGVRYHIVRGTLDAVGVKDRQQGRSYGVKKPK
What is the function of this protein?
With S4 and S5 plays an important role in translational accuracy.  Located at the interface of the 30S and 50S subunits (By similarity).
What are the official names of this protein?
30S ribosomal protein S12, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL3_FLAPJ
Sequence: MSGLIGRKIGMTSIFDENGKNIPCTVIEAGPCVVTQVRTIGVDGYEALQLGFDDKNEKHSTKADLGHFKKAGTVAKKKVVEFQDFVSEHKLGDVISVDLFSEGEFVDIQGVSKGKGFQGVVKRHGFGGVGQATHGQHNRLRAPGSVGASSYPSRVFKGMRMAGRMGGDNVKVQNLRVLKVVAEKNLLVIKGCIPGCNNSYVIIQK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: YBJL_ECO81
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBL1_ARATH
Sequence: MARDRREGLEIKVVNPPAAATNNVAVETSPATATRRRRQQQRASFAEFRPFKLWFPWLVPAIVVANIALFAISMFINNCPKNSAYCLARFLGRFAFQPMKENPLLGPSSLTLEKMGALDVSMVVHKHEVWRLFTCIWLHAGVFHVLANMLSLIFIGIRLEQEFGFVRIGLLYMISGFGGSLLSSLFNRAGISVGASGALFGLLGAMLSELLTNWTIYANKFAALLTLIFIIAINLAVGILPHVDNFAHLGGFTSGFLLGFVFLIRPQYGYFNQRNNPRGYAAPSAKSKHKPYQYVLWITSLVLLIAGYTAGLVVLLRGTDLNKHCSWCHYLSCIPTSLWSCKSQNVYCESSQIGQQMNLTCITNGKTEMYKLSNDIPSRIQQLCSQLCR
What is the function of this protein?
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.  Unable to cleave the Drosophila protein Spitz.
What are the official names of this protein?
RHOMBOID-like protein 1, AtRBL1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: SPEE_YERE8
Sequence: MSQKELWYETLHANFGQYFSVENVLYREKTEHQDLVIFENPVLGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGQAKKVLIIGGGDGAMLREVSRHKNIEQITMVEIDAGVVEFCRQYLPNHSAGAYDDPRFKLVIDDGVNFVNQTTEKFDVIISDCTDPIGPGESLFTSAFYEGCARSLNEGGIFVAQNGVCFLQQDEAVDSHNKLSHYFKDVSFYQAAIPTYYGGIMTFAWATQNRQLRQLDITTLQQRFVEAGLTCRYYNPAIHVGSFALPQYLLDALTTKR
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_ENT38
Sequence: MIKQRTLKRIVQATGVGLHTGKKVTLTLRPASANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVDAPEIPIMDGSAAPFVYLLLDAGIEELNCAKKFVRIKETVRVEDGDKWAEFKPFNGFSLDFTIDFNHPAIDASTQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAFKSGHALNNKLLQAVLAKQEAWEYVTFEDEAELPLAFKAPSTVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: CD302_PIG
Sequence: MARAAPPALLLPLLGLAAATAAAAAAAAAVGCPSSTWVQFQDSCYIFLQEAIKVESIEDVRNQCTDHGADMVSIHNEEENTFILETLKKQWKGPDDILLGMFFDTDDASFKWFDKSNMTFDKWSDQEDGEDLVDTCAFLHTKTGEWKKGNCEVSSVEGTLCKAAIPYEKKYLSDNHILISALVIASTVILTVLGAVIWFLYKRNLDSGFTTVFSTAPQSPFNDDCVLVVAEENEYAVQFD
What is the function of this protein?
Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration.
What are the official names of this protein?
CD302 antigen, Type I transmembrane C-type lectin receptor DCL-1.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Cell projection, filopodium. Cytoplasm, cell cortex. Note=Colocalizes with F- actin in filopodia, cellular cortex and microvilli of the apical cell surface.
Protein: CM046_HUMAN
Sequence: MEKDTGTTHRRHRPGLRALPSGVALGHLKAASEASELQRSRSLGGLQPEGDPPSRPRKPHKELESEDQGKDPSSNAEDASCQKNLAQDKKESFSTLGKLGHESGKQDPEREKSDLEASMQEVQEGEHADGGLQEAKEQEAESIKLNDLQEEEKASVFVEIDLGDHAEEVVTDAKKEEKPSQMDVEDLSEDEMQTSWVCCIPYSTRKRAKEST
What are the official names of this protein?
Uncharacterized protein C13orf46.
Protein: MDHG_CUCSA
Sequence: MQPIPDVNQRIARISAHLHPPKYQMEESSVLRRANCRAKGGAPGFKVAILGAAGGIGQPLAMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQQQLERALTGMDLVVIPAGVPRKPGMTRDDLFKINAGIVKTLCEGIAKCCPTAIVNLISNPVNSTVPIAAEVFKKAGTYDPKRLLGVTMLDVVRANTFVAEVLGLDPRDVNVPVVGGHAGVTILPLLSQVKPPSSFTQEEINYLTDRIQNGGTEVVEAKAGAGSATLSMAYAAVKFADACLRGLRGDAGVVECAFVSSQVTELPFFATKVRLGRNGIDEVYSLGPLNEYERIGLEKAKKELAGSIEKGVSFIRG
What are the official names of this protein?
Malate dehydrogenase, glyoxysomal.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: REDAM_ASPOR
Sequence: MSKHIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLIIICLLNNQVVEDALRDALQTLPSKTIVNLTNGTPNQARKLADFVTSHGARYIHGGIMAVPTMIGSPHAVLLYSGESLELFQSIESHLSLLGMSKYLGTDAGSASLHDLALLSGMYGLFSGFLHAVALIKSGQDTSTTATGLLPLLTPWLSAMTGYLSSIAKQIDDGDYATQGSNLGMQLAGVENIIRAGEEQRVSSQMILPIKALIEQAVGEGHGGEDLSALIEYFKVGKNVD
What is the function of this protein?
NADPH-dependent reductive aminase that catalyzes the reductive coupling of a broad set of carbonyl compounds with a variety of primary and secondary amines (Ref. 2).  Possesses remarkably high activity for the reductive amination of ketones and amines, often with high stereoselectivity and in some cases with ketone:amine ratios as low as 1:1 (Ref. 2).  The cofactor NADPH, the carbonyl compound and the amine are added to the enzyme in that sequence, followed by the release of product, NADP(+) being released at last (Ref. 2).  RedAm is also able to act in the reverse, oxidative direction and exhibits activity in the dehydrogenation of amines to yield imines (Ref. 2).  The highest activity is found for 1-methyl-tetrahydroquinoline and acyclic amines are also found to be transformed (Ref. 2).
What are the official names of this protein?
NADPH-dependent reductive aminase, RedAm.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family.
Protein: FUME_SHIFL
Sequence: MATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQDETPGFADDITWDFISNVNSITRNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAVTTTLKELTP
What is the function of this protein?
In vitro catalyzes the addition of water to fumarate, forming malate.  Cannot catalyze the reverse reaction.  Cannot use the cis-isomer maleate as substrate.
What are the official names of this protein?
Fumarase E.
What is the protein family that this protein belongs to?
Belongs to the MtlR/FumE family.
Protein: YAAI_ECO24
Sequence: MKSVFTISASLAISLMLCCTAQANDHKILGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: PYRG_BURM7
Sequence: MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLKVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFISTKMRKANNFTTGQIYESVIRKERRGDYLGKTVQVIPHITNEIQAFIERGAASATCGEPDVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNSACFVHLTLVPFIATAGELKTKPTQHSVQKLREIGISPHVLLCRADRPIPDDESKKISLFSNVPEDAVISVWDVDSIYKIPQMLHDQGLDRLICEELRLDPQPADLRMWAALVEKLQNPKHEVTIGMVGKYVDLTESYKSLIEALRHASIHTSTKVNIEYIDSEELETNGTASLAHLDAVLVPGGFGRRGTEGKIAAVRYAREAKVPYLGICLGMQLAVIEFARDVVGLKQANSTEFDPNTPERVVALITEWYDREGKVEKRTEDSDLGGTMRLGSQRCPIKPGTLAEAIYGKDVNERHRHRYEVNNRFVPQLEAGGLVISARTPSEDLPEMMELPSTMHPWFVGVQFHPEFTSTPRDGHPLFKSFVQAALACQQTRAGAKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: KDSB_PSYWF
Sequence: MTLVSDLALPKPKVHIVIPARFKSTRLPGKPLLEIHGKPMILWVAQKASQATFADDLCIATDDERIAAVCQQAGYEVVMTDAHHASGTDRLSEVAQKKGWDAEDIVVNMQGDEPLVPPQLLEQVKDLLVNKPDCVMATLYELILDYQEFIRPSVVKVVTDNLKHALYFSRAPIPCDRDHAMAMVQQPEGSHQPPLTVPKQAYRHLGIYAYRVKLLQDFVRWSPGILENLESLEQLRVLENGGKIAIEAASVQLPPGVDLQEDLDRLNALPISELQ
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERA_BORBU
Sequence: MKSGFAAILGRPSTGKSTLLNSICGHKISIISPIPQTTRNNIKGIFTDDRGQIIFIDTPGFHLSKKKFNIAMMKNIHSSIGEVELILYIIDIQDKPGEEENKMLEIIKNSKIKFLVILNKIDLKNTKIKEITQFLKEKGIEDSNIIKISAEKKINTEELKNKIYENFSEGPLYYPQEYYTDQEINFRISEIIREKAIENLKEELPYSLYVDIDTLENKKGSLFIRANIFVANESQKGIIVGKNGKEIKSIGERARKTIAKIFETKCNLFLQVKLKKNWNKEDKLIKRLIN
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: RDM3_ARATH
Sequence: MDRKGKGKQVAGSDSYSGGQKRKNSVEFRDEGLRIKKRKNPEVLQFFEESAEVGYYGGSSDEDDDGLGFLNDMEDEPEVEESSKAGKGEKGKSSFVFPKEEDLNEEEFDRIMEERYKPGSGFLRYADDDIKDAIEMDALAPTSKDPPIWKVKCAIGRERRSVFCLMHKFVELRKIGTKLEIISVFSVDHVKGFIFIEADKEHDVLEACKSLVGIYATRMVLLPKAETPNLLTVQKKTKKVSEGTWARVKNGKYKGDLAQIVAVSDTRNKALIKLIPRIDIQALTQKYGGGVTVQKGQTPAPRLISSSELEEFRPLIQVRRDRDTGITFEHLDSLMLKDGYLYKKVSLDSISSWGVIPTKDELLKFTPVDRKETGDVEWISEIYGEERKKKILPTCREGGKGEGSGGGKGEGSGGGKGEGSRGGKGEGSSDFKSESSYELYNLVCFSRKDFGLIVGVDDKGDGYKVLKEGIDGPVVVTVGKKEMQNGPFDSKFTALDLNKKQISVNDVVKISKGPSEGKQGVVRQVYRGIIFLYDESEEENGGYFCCKSQSCEKVKLFTEESNEKTGGFDGTAFEDFVSSPKSPLSPEKEWQPRERYNSSNQGDIGSTYSIGQKLRIRVGPLKGYLCRVIALRYSDVTVKLDSQHKIFTVKSEHLAEVRDRNTVLSTSGDAGTGSFQPFGMLGTESSTGDWAIGAGTSSEGGNWNIGGPSTDSHESLNIERNMVQLCREKNPWGGSKPTSDVSPTVADDNTSAWANAAAENKPASASDQPGGWNPWGKTPASEAGTVSGWGDTSASNVEASSWEKQGASTSNVADLGSWGTHGGSSGGNKQDEDSVWGKLCEASESSQKKEESSWGKKGGSDGESSWGNKDGNSSASKKDGVSWGQQDKGSDESKGGSAWSNQCGDFGSGKKKDGSSGWNKSAEDSNANSKGVPDWGQPNDGSSWGKKGDGAASWGKKDDGGSWGKKDDGNKDDGGSSWGKKDDGQKDDGGSSWEKKFDGGSSWGKKDDGGSSWGKKDDGGSLWGKKDDGGSSWGKEDDGGSLWGKKDDGESSWGKKDDGESSWGKKDDGGSSWGKKDEGGYSEQTFDRGGRGFGGRRGGGRRGGRDQFGRGSSFGNSEDPAPWSKPSGGSSWGKQDGDGGGSSWGKENDAGGGSSWGKQDNGVGSSWGKQNDGSGGGSSWGKQNDAGGGSSWGKQDSGGDGSSWGKQDGGGDSGSAWGKQNNTSGGSSWGKQSDAGGGSSWGKQDGGGGGSSWGKQDGGGGSGSAWGKQNETSNGSSWGKQNDSGGGSSWGKQDGGGGGSSWGKQNDGGGGSSWGKQGDGGSKPWNEHSGGGRGFGERRGGGGFRGGRNQSGRGGRSFDGGRSSSWKTDNQENTWKSDQSGGSDWKKGWGEDSNNSKPSGSSAGGCAGNWPSWDTNSKKETNDKPGDDSKSAWGTSNDQVNTDNNNDSWNKKPNNDVGTSGEADNAWGGKTNAVAPSPSGSAAWGTGDKKTGW
What is the function of this protein?
Effector of RNA-directed DNA methylation (RdDM) triggered by small interfering RNAs (siRNAs, 24-nt RNAs).  Functions as an adapter protein that binds scaffold transcripts generated by polymerase V and recruits AGO4 and AGO4-bound siRNAs to form an RdDM effector complex (PubMed:19410546, PubMed:19343051).  Promotes the expression of 24-nt RNAs (PubMed:19343051).  Required for the initial establishment of DNA methylation (PubMed:21150311).  Together with AGO4, required for transcriptional gene silencing (TGS) by DNA methylation and repressive histone modifications (H3K9me2) of several chromatin loci (PubMed:21738482).
What are the official names of this protein?
Protein RNA-directed DNA methylation 3, KOW domain-containing transcription factor 1, Protein SPT5-like.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=Localized at punctate nuclear foci. Colocalizes with AGO4 and polymerase V in the nucleoplasm.
Protein: RS15_ACIB3
Sequence: MALTNADRAEIIAKFARAENDTGSPEVQVALLTAQINDLQGHFKAHKHDHHSRRGLIRMVNQRRKLLDYLNGKDHERYTALIGALGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.