PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_PORGI
Sequence: MERIRLDLSKTGSSVASYGETAEKFNALLDNGTGRGSDFLGWVHLPSSITEEELNAVEAAATILRERCDYVINVGIGGSYLGARAVIEALQNSFEAYRSDRENPVILYAGNNIGEDYLSELLQFLRDKRFGIIYISKSGTTTEPAIAFRLLKGLLESQVGREDARERIVAVTDSAKGALRRMADEEGYRSFVIPDNVGGRFSVLTPVGLLPVAVAGFDIRQLVRGAADMQAMTASDIPFSDNPALRYAAARNALYAEGKKIEILANFHPKMHYIGEWWKQLFGESEGKEEKGIFTATVDLTTDLHSMGQWMQEGERTIFETVISVENQDTCLTIPSDSADLDGLNFLAGKRVDEVNKMAELGTRLAHVDGGVPNIRIILPQLDAYYIGQLFYFFEKAVGVSGYMLGVNPFDQPGVEGYKNNMFALLNKPGYETESAAMAGRLKEC
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXB_PHOLL
Sequence: MATISSIDSLRPLTIGLIAGETSGDILGAGLIRALKAKVPNARFVGVAGPLMQAEGCEAWYEMEELAVMGIVEVLGRLPRLLKIRKDLTTRFTELKPDVFVGIDAPDFNITLEGRLKQRGIRTIHYVSPSVWAWRQKRVFKIGKATDMVLAFLPFEKAFYDKFNVPCRFIGHTMADAMPLQPNKATARELLGILPESVCLALLPGSRHSEVEMLSADFLKTAQLLKRNIPDLHVFVPLVNAKRREQFERIKQEVAPELNVHLVDGKAREIMIASDAALLASGTAALECMLAKCPMVVGYRMKPLTFWLAKRLVKTPYVSLPNLLSGEELVKELLQEKCQPQKLADELLPLLQGSEKVGALKQTFLHLHKSIRCNADEQAAQAVLELAGK
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: YFBU_SALTI
Sequence: MEMTNAQRLILSNQYKMMTMLDPTNAERYRRLQTIIERGYGLQMRELDREFGELTEETCRTIIDIMEMYHALHVSWTNLKDTQAIDERRVTFLGFDAATEARYLGYVRFMVNIEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQIINA
What are the official names of this protein?
UPF0304 protein YfbU.
What is the protein family that this protein belongs to?
Belongs to the UPF0304 family.
Protein: THIE_STAAC
Sequence: MFNQSYLNVYFICGTSDVPSHRTIHEVLEAALKAGITLFQFREKGESALKGNDKLVLAKELQHLCHQYDVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIAQYFTDKIIGLSISDLDEYAKSDLTHVDYIGVGPIYPTPSKHDAHIPVGPEMIATFKEMNPQLPIVAIGGINTNNVAPIVEAGANGISVISAISKSENIEKTVNRFKDFFNN
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: BLAC_STRLA
Sequence: MGTTGARPSRRAVLTAAAGAAVAGIPLGGSTAFAAPRGNPDVLRQLRALEQEHSARLGVYARDTATGRTVLHRAEERFPMCSVFKTLAVAAVLRDLDRDGEFLATRLFYTEQEVKDSGFGPVTGLPENLAAGMTVERLCAAAICQSDNAAANLLLRELGGPEAVTRFCRSVGDRTTRLDRWEPELNSAEPGRLTDTTTPRAIGATYGELVLGDALAPRDRERLTGWLLANTTSTERFRKGLPADWTLGDKTGGGAYGTNNDAGVTWPPHRPPVVMVVLTTHDRPDAVADNPLVAKTAALLASALG
What are the official names of this protein?
Beta-lactamase, Penicillinase.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: MTEFE_ARATH
Sequence: MASKLKTFINLRDYPITLFNQIRSLSSRILTPINQSHYRKRILLANLLQRYGFPPSSLQHFLSRNNHLLNSDLVETEISLGILLSLKIPQKSLVSLISDCPNVLRSEFLRKWRVPLSNCGKHGVVSSSAIKSVLEHSSRIGIGPDKFNECVRVLKSLGFCDSTVSRILSSFPGVLLVNEIEIRRKIEFLVGIGIARDNIERFFHVFPEVLGIGTETRLKPLLDEFMKMGFSKDDVKKEIAREPRVLGLELGELPRCLELINTLKCREVIRVSIISEGAFRAGFEVKLRVDCLCKYGLIRRDAFKVVWKEPRVILYEIEDIEKKIEFLTNRMGFHINCLADVPEYLGVNLQKQIVPRYNVIDYLKLKGGLGCDIGLKGLIKPSMKRFYNLYVMPYPECERIFGKRKENVRVNKRHPAGLWKLMKPPSNLTTKEDVQNMKSFIESLA
What is the function of this protein?
Transcription termination factor required for mitochondrial NAD2 intron 3 splicing and normal membrane respiratory chain Complex I activity.  Essential for normal plant growth and development.  Binds to RNA but not to double-stranded DNA.
What are the official names of this protein?
Transcription termination factor MTERF15, mitochondrial, Mitochondrial transcription termination factor 15.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PIR7B_ORYSJ
Sequence: MEISSSSKKHFILVHGLCHGAWCWYRVVAALRAAGHRATALDMAASGAHPARVDEVGTFEEYSRPLLDAVAAAAAPGERLVLVGHSHGGLSVALAMERFPDKVAAAVFVAAAMPCVGKHMGVPTEEFMRRTAPEGLLMDCEMVAINNSQGSGVAINLGPTFLAQKYYQQSPAEDLALAKMLVRPGNQFMDDPVMKDESLLTNGNYGSVKKVYVIAKADSSSTEEMQRWMVAMSPGTDVEEIAGADHAVMNSKPRELCDILIKIANKYE
What is the function of this protein?
Exhibits esterase activity towards naphthol AS-acetate in vitro.
What are the official names of this protein?
Esterase PIR7B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: ATPA_PSYA2
Sequence: MQQLNPAEISNLIKQRIQDLDAGATAKNEGTIVKVSDGIVQIHGLEDAMYGEMIEFEGEVYGMALNLERDSVGAVVLGDFLKLQEGQKAYCTGRILEVPVGPELLGRVVDALGNPIDGKGPINAKMTDKVEKIAPGVIDRQSVDQPVMTGYKSVDTMIPIGRGQRELIIGDRQTGKTAMAIDAIIAQKASGIKCVYVAIGQKRSTIANVVRKLEQTGALEYTTVVVASASEPAALQYIAPYSGCTMGEYFRDRGEDALIVFDDLSKQAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERASRVNAAYVEKFTNGEVVGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESSLFNSGIRPAVNAGISVSRVGGAAQTKIIKKLSGGIRTALAQYRELAAFAQFASDLDDATREQLDHGERVTELMKQKQYQPMSISEQAAVIYASNEGFLADVPVEKIGSFEEAYLRYMHDEQADLMKEIDDTANYNDDIAGRLKLSLETFKQNHSY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: C513D_DICDI
Sequence: MGISSIIIILFIIVLLKKLIKKEDRIHRINKNIPGPKSKLLVGNLFDLKGQVHEKLKEWYEQYGSVYRIEFGSVSTVVLTEYATLKEAFVDNGEIFQSRFQRKSRTTCNKGLNLANSNGEYFNHLKKTLSNEITNQKMKKNEKIIKIQVGLLSEFFNEISGGGGGGSGGSGISKEPINNIIKMYSLNVMLSLLFNIHFPYNNNSYQDELMSTITRYFKSTGLPYPSDFIPILYPFLKNKPKEYFEDYESVKKLITRITNEYQLKHMTEISNKSTIEEIENYQPTNILESLLKQYRLNKIPYDGVIGCLMDLILAGSDTTGNTCLFSLVALVNNSNIQEKLFNEISNAFNDDDGDELNGANDISNSLLKLSYFSDRIKTPYLVAFIKEVKRYYPCAPLSVPHLLTEDCEIQGYKIAKGTQVIQNIYSTHLSQSFCSNPLEFSPERFLDSTNEPKIITFGIGQRKCPGENIFEIEIYIFLVYLIKKFKFSHPIDDNLQLNDRGQFGLSLQCPQLNIKVESR
What are the official names of this protein?
Probable cytochrome P450 513D1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ACYP_NOCSJ
Sequence: MCGRPGDDGDMRSAVDVTVTGRVQGVSFRYYADREADRLGVAGWVRNEPDGTVAAHVEGDPGAVAAFVRWCHDGPRLAHVEQVDVRDGTDQGLRSFGVR
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: LCAP_HUMAN
Sequence: MEPFTNDRLQLPRNMIENSMFEEEPDVVDLAKEPCLHPLEPDEVEYEPRGSRLLVRGLGEHEMEEDEEDYESSAKLLGMSFMNRSSGLRNSATGYRQSPDGACSVPSARTMVVCAFVIVVAVSVIMVIYLLPRCTFTKEGCHKKNQSIGLIQPFATNGKLFPWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTFMSAVSSQEKQAEILEYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFSYTDESNEKKYFAATQFEPLAARSAFPCFDEPAFKATFIIKIIRDEQYTALSNMPKKSSVVLDDGLVQDEFSESVKMSTYLVAFIVGEMKNLSQDVNGTLVSIYAVPEKIGQVHYALETTVKLLEFFQNYFEIQYPLKKLDLVAIPDFEAGAMENWGLLTFREETLLYDSNTSSMADRKLVTKIIAHELAHQWFGNLVTMKWWNDLWLNEGFATFMEYFSLEKIFKELSSYEDFLDARFKTMKKDSLNSSHPISSSVQSSEQIEEMFDSLSYFKGSSLLLMLKTYLSEDVFQHAVVLYLHNHSYASIQSDDLWDSFNEVTNQTLDVKRMMKTWTLQKGFPLVTVQKKGKELFIQQERFFLNMKPEIQPSDTSYLWHIPLSYVTEGRNYSKYQSVSLLDKKSGVINLTEEVLWVKVNINMNGYYIVHYADDDWEALIHQLKINPYVLSDKDRANLINNIFELAGLGKVPLKRAFDLINYLGNENHTAPITEALFQTDLIYNLLEKLGYMDLASRLVTRVFKLLQNQIQQQTWTDEGTPSMRELRSALLEFACTHNLGNCSTTAMKLFDDWMASNGTQSLPTDVMTTVFKVGAKTDKGWSFLLGKYISIGSEAEKNKILEALASSEDVRKLYWLMKSSLNGDNFRTQKLSFIIRTVGRHFPGHLLAWDFVKENWNKLVQKFPLGSYTIQNIVAGSTYLFSTKTHLSEVQAFFENQSEATFRLRCVQEALEVIQLNIQWMEKNLKSLTWWL
What is the function of this protein?
Release of an N-terminal amino acid, cleaves before cysteine, leucine as well as other amino acids.  Degrades peptide hormones such as oxytocin, vasopressin and angiotensin III, and plays a role in maintaining homeostasis during pregnancy.  May be involved in the inactivation of neuronal peptides in the brain.  Cleaves Met-enkephalin and dynorphin.  Binds angiotensin IV and may be the angiotensin IV receptor in the brain.
What are the official names of this protein?
Leucyl-cystinyl aminopeptidase, Cystinyl aminopeptidase, Insulin-regulated membrane aminopeptidase, Insulin-responsive aminopeptidase, IRAP, Oxytocinase, OTase, Placental leucine aminopeptidase, P-LAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=In brain only the membrane-bound form is found. The protein resides in intracellular vesicles together with GLUT4 and can then translocate to the cell surface in response to insulin and/or oxytocin. Localization may be determined by dileucine internalization motifs, and/or by interaction with tankyrases. SUBCELLULAR LOCATION: [Leucyl-cystinyl aminopeptidase, pregnancy serum form]: Secreted. Note=During pregnancy serum levels are low in the first trimester, rise progressively during the second and third trimester and decrease rapidly after parturition.
Protein: Y1323_BIFAA
Sequence: MLNIMEVHETNKMIEQEKLDVRTITMGISLLDCAADSVDEVCENIYNKITTYAKDLVSTGRAIERDFGIPIVNKRITVTPISLVGASSCKSSEDFVKIAHALDRAAKKVGVDLIGGYSALVSKSMTPAEEMLIRSLPQALSETDIVCSSVNVGSTKTGIDMNSVELLGHIVKDIAHATADNDSYGCVKFVAFCNAPDDNPFMAGGFHGVTEGDAVINVGVSGPGVVSRALDEAKGKDFEFLCETIKRTAFKITRVGQLVAQEASRRLGIPFGIIDLSLAPTPAVGDSVGEVLEKIGLEQVGAPGTTAALAMLNDQVKKGGIMASSYVGGLSGAFIPVSEDKNMIDAANNGCLKIEKLEAMTCVCSVGLDMIAIPGDTTAATISGIIADEAAIGMVNQKTTAVRVIPVEGKGVGEMANFGGLMGYAPIIPVNQTSCEAFVTRGGRIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein BAD_1323.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: SHT1_ORYSJ
Sequence: MKLDSFMVTRRGNPELVAPARATPRGTKPLSDLDDDWDLRYLQPCLEFFRAVDDGERRKPARPGDAIRAALAEALVYYYPIAGRLRELPKGGRLAVECTGEGVVFVEAEADVRIEDLGEPPLPTFRGAESFLCDVGDAGVVVGRPLFYMQITHLKCGGFVLGTHICHCIADAFGTLQFLKAIVDIARGEAKPTTLPVWEREHFVATSLPPNIKEEQEKLFDELENTTCDDIMVTMPAENMVSEYFTISQRDMIALRRHVPFNLTKTVTSFELLTAVLWRSRTMALGYKPCQIVRLMITVNARGRWKKLPLGYYGNGLLCPVIEITVNDLCTNSLGHTIELVRKAKHEMKTKENMQLMVDLLPLWREKPYIKVERIFETCDIKWIGQDTLDIGWAKRIGGGIPTVSLPDMTSYQFMCKNEKGDHILVFHTTNAVMHLPLVIKRK
What is the function of this protein?
Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from p-coumaryol-CoA to spermidine, to produce coumaroyl spermidine.  Can use feruloyl-CoA as acyl donor.  Contributes to the natural variation of spermidine-based phenolamides in rice cultivars.
What are the official names of this protein?
Spermidine hydroxycinnamoyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: KAD_CLONN
Sequence: MRMILLGPPGAGKGTQAKLISEKYSIPHISTGDIFRKNISEKTPLGVKAKEYMDKGQLVPDELTIDLVNDRLTHEDCKKGFLLDGFPRTVKQAEALEKFLTENNQSLDTALLIDVPSSFILERMTGRRVCPSCGASYHIKFNPPKIEGLCDVCKKEVIQRKDDTEETVKERIEVYDRQTQPLVDFYSSKDQLFVVDGTQSIDQVFETISNHIEGDK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1617_SHELP
Sequence: MKLTSHEARVIGCLLEKEKTTPEQYPLSLNGLTLACNQKSSREPVMNLSEADTQAALDSLAKKRLVAEQSGFGSRVVKYKHRFCNTEFSDLQLSEDKVAIICLLLLRGPQTAGELRTRSNRLYGFNDVAQVEQALNSLAQMEPALVRQLPREPGKRESRFIELISEAETQLDTQLATQPAQASSLANDELVERVALLEQQVAELKLQVAELLGKI
What are the official names of this protein?
UPF0502 protein Shew_1617.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: PYRH_STRP3
Sequence: MEPKYQRILIKLSGEALAGEKGVGIDIPTVQAIAKEIAEVHVSGVQIALVIGGGNLWRGEPAADAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQTAIPMQNVAEPYIRGRALRHLEKNRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMAKNGVDGVYNADPKKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMNEAGNIQRVVFGEHIGTTVSNKVCD
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNU13_USTMA
Sequence: MSAPNPKAFPLADATLTNQILDLIQQASHYKQLKKGANEATKTLNRGICEFIVMAADVEPIEIVLHLPLLCEDKNVPYVFVPSKTALGRACGVSRPVVSASVTTNEARELQSQIQTVKLAIERLLI
What is the function of this protein?
Common component of the spliceosome and rRNA processing machinery.  In association with the spliceosomal U4/U6. U5 tri-snRNP particle, required for splicing of pre-mRNA.  In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs.  Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity).
What are the official names of this protein?
13 kDa ribonucleoprotein-associated protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TPIS_CHLT2
Sequence: MFTDKETHRKPFPTWAHLLHSEPSKQFVFGNWKMNKTLTEAQTFLKSFLSSDILSNPQIITGIIPPFTLLSACQQAVSDSPIFLGAQTTHEADSGAFTGEISAPMLKDIGVDFVLIGHSERRHIFHEQNPVLAEKAAAAIHSGMIPVLCIGETLEEQESGATQDILLNQLTIGLSKLPEQASFILAYEPVWAIGTGKVAHPDLVQETHAFCRKTIASLFSKDIAERTPILYGGSVKADNARSLSLCPDVNGLLVGGASLSSENFLSIIQQIDIP
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFW_RHIEC
Sequence: MCRCSADSSPVDVKDILNRLKSLSAAEEFFEALGVPYDPKVLDVSRLHIMKRMGQYLAAEDFSHLPDRVIAARARAILERAYCDFATSAPLSHRVFKVLKDHNPNRPVTPGRTVVPLDSFLKPFEKK
What is the function of this protein?
May protect the nitrogenase Fe-Mo protein from oxidative damage.
What are the official names of this protein?
Nitrogenase-stabilizing/protective protein NifW.
What is the protein family that this protein belongs to?
Belongs to the NifW family.
Protein: GAPN_STRMU
Sequence: MTKQYKNYVNGEWKLSENEIKIYEPASGAELGSVPAMSTEEVDYVYASAKKAQPAWRSLSYIERAAYLHKVADILMRDKEKIGAVLSKEVAKGYKSAVSEVVRTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAFKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIGERIGKMAGMRPIMLELGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVKRVLVMESVADELVEKIREKVLALTIGNPEDDADITPLIDTKSADYVEGLINDANDKGAAALTEIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVTSVEEAIEISNKSEYGLQASIFTNDFPRAFGIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGIQGVKYSIEAMTTVKSVVFDIK
What are the official names of this protein?
NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)], Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase, Triosephosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: SLS4_TRYB2
Sequence: MISYPFFSLSPPGLVPPPMAVPPVEMYSGSFWNRMRKPLPLRTQVIRFTVVFVIVSFILAVALQITHERMPDPKVTKPLPDLGFELLTKVPGMYVLADCCIGFLNILSVFTAFKLYLLHRHCVGSGEPELPCNIPGVSRFFLSVWLCKENCRIELRNVHTIAWIRFITSYALLLLFRSVVIVMTSLPAPDDLCQDPPKIENPVKNVILTVLTAGGGSIHCGDLMYSGHTVILTLHLMFHWIYGAMVHWSFRPVVTVVAIFGYYCIVASRFHYTDDVLVAIYLTIATFIAVGHNADGAPWQLQLFIRWLPCCGANSREMTEDSQPVMVAFKSEELDEMNGVLEGRQKKHGGVGDGEALMFKCGAYV
What is the function of this protein?
Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa.  Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors.  Directly and specifically recognizes the choline head group on the substrate.  Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate.  Does not function strictly as a SM synthase.  Essential for viability of the pathogenic bloodstream stage of this human protozoan parasite and, consequently, can be considered as potential drug target (By similarity).
What are the official names of this protein?
Phosphatidylcholine:ceramide cholinephosphotransferase 4, Ethanolamine-phosphorylceramide synthase, EPC synthase, Sphingolipid synthase, Sphingomyelin synthase, SM synthase.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: ATPI_SORBI
Sequence: MNITPCSIKTLKGLYDISGVEVGQHFYWQIGGFQIHAQVLITSWFVITILLGSVIIAVRNPQTIPTDGQNFFEYVLEFIRDLSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIELPHGELAAPTNDINTTVALALLTSAAYFYAGLSKKGLSYFEKYIKPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: TRMB_SODGM
Sequence: MSNNVISPEFDEQGRALRRIRSFVRRQGRLTKGQQYALDTLWPAMGTDYQAQPLDLTALFGRAAPVTLEIGFGMGASLVTMAAAHPEQNFIGIEVHLPGVGACLASAQEAGVSNLRVMCHDAVEVLEQMIPDASLALVQLFFPDPWHKARHNKRRIIQAPFVELVGRKLAAGGVFHMATDWQPYAEHMLAVMSDAAFFRSLSSTGDYVPRPASRPLTKFEQRGQRLGHGVWDLMFAKTV
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: CPFC_BACP2
Sequence: MEKKKMGLLVMAYGTPYKEEDIERYYTHIRRGRKPEPEMLQDLKDRYKAIGGISPLSKITEQQAHGLCEHLNDIQDDIEFHVYIGLKHIEPFIEDAVADMHKDGITEAVSIVLAPHFSTFSVKSYNKRAQDEADKLGNLQITSVESWYDEPKFVDYWVKQVKDTYASMSQEERDSAVLIVSAHSLPEKIIAAGDPYPDQLAQSAKMIAEGAGIEHYEIGWQSEGNTPDPWLGPDVQDLTRDLFEQKGYQTFVYVPVGFVADHLEVLYDNDYECKVVTDEIGAAYYRPEMPNAKPAFIDALATVVLKKLDESK
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROR2_MOUSE
Sequence: MARGWVRPSRVPLCARAVWTAAALLLWTPWTAGEVEDSEAIDTLGQPDGPDSPLPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPVVQEPRRVIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGLKTITATGVLYVRLGPTHSPNHNFQDDDQEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTQLSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLENDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIPAERLGRYHQCYNGSGADYRGMASTTKSGHQCQPWALQHPHSHRLSSTEFPELGGGHAYCRNPGGQVEGPWCFTQNKNVRVELCDVPPCSPRDGSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLISQHKQAKLKEISLSTVRFMEELGEDRFGKVYKGHLFGPAPGEPTQAVAIKTLKDKAEGPLREEFRQEAMLRARLQHPNIVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHVVAQIAAGMEFLSSHHVVHKDLATRNVLVYDKLNVRISDLGLFREVYSADYYKLMGNSLLPIRWMSPEAVMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRSRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRSWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYMAPKQKAQPFPQPQFIPMKGQIRPLVPPAQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSVADRAALLSEGTEDAQNIAEDVAQSPVQEAEEEEEGSVPETELLGDNDTLQVTEAAHVQLEA
What is the function of this protein?
Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes.  It seems to be required for cartilage and growth plate development (PubMed:10700181).  Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.  In contrast, has also been shown to have very little tyrosine kinase activity in vitro.  May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase transmembrane receptor ROR2, mROR2, Neurotrophic tyrosine kinase, receptor-related 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: KDGD1_STRAW
Sequence: MTSAPLAARLSIPSGPLFFPVTAYRPDGALNLDVYREHVRRGVEAGAAAVFACCGTGEFHALAPEEFERCVGAAVEETAGRVPVVAGAGYGTALAVRFARLAQDAGADGLLAMPPYLVVAGQEGLLRHYRELAAATSLETIVYQRDNAVFTPEAVVELARTDGIIGFKDGLGDLDLMQRVVSAVRTEVPGDFLYFNGLPTAELTGLAYRGIGITLYSSAVFCFAPEIALAFHKALNSGDDATVNRLLDGFYRPFVDLRAQGRGYAVSLVKAGVRLRGLDVGEVRPPLHEPTEDHVKQLAQLVDRGYALLQEGM
What are the official names of this protein?
Probable 5-dehydro-4-deoxyglucarate dehydratase 1, 5-keto-4-deoxy-glucarate dehydratase 1, KDGDH 1.
What is the protein family that this protein belongs to?
Belongs to the DapA family.