PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_STAAE
Sequence: MNKNKPFIVVIVGPTASGKTELSIELAKRINGEIISGDSMQVYKHMNIGTAKVTPEEMDGIPHHLIDILNPDDTFSAYEFKRLAEDLITDITNRGKVPIIAGGTGLYIQSLIYNYELEDETVTPAQLSIVKQKLSALEHLDNQQLHDYLAQFDAVSAENIHPNNRQRVLRAIEYYLKTKKLLSNRKKVQQFTENYDTLLLGIEMSRKTLYSRINKRVDIMLDHGLFREVQQLVEQGYESCQSMQAIGYKELIPVINGQMIYEDAVNDLKQHSRQYAKRQMTWFKNKMSVHWLDKENMSLQMMLDEITTQIK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: KDPC_XANC8
Sequence: MSTSLPLRDDGAVRASFALALFVLLGLGLGYSLVATGITSALMPDQAHGSLLRADGRVIGSSLVAQPFADARYFQPRPSAAKYDPTAAAGSNQARSNPELLARIATARAEIAQRDGIAPDAVPGELLTQSGSGLDPHLSPAGAQVQLRRVAAARGWPEQRVAALLQAATEQPQFGLLGQPRINVLALNLALDRAGDGVPGTENGVEQQR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RL27_TRIV2
Sequence: MAHKKGTGSTRNGRDSNAQRLGVKRFGGQAVIAGNILVRQRGTKFHAGNNVGIGKDDTLFALVDGVVTFERKGKSRKKVSVYPAAAAAEAVAG
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: CMPB_SYNP6
Sequence: MVTARETRRNGSRPSGLKKWRQKLDGILLPLAGILGFLIIWQIFSSSGATRLPGPLSLFTEERTRELLLYPFLDRGGLDKGLFWQTIASLTRVAQGFSIAAIIGISVGILVGLNRQLNAMLDPLFQFLRMIAPLAWVPIALVAFQQNQPAAIFVIFITAVWPILINTAEGVRQIPQDYNNVARVLRMSKSKYLMKVVLPAALPYIFTGLRIAIGLSWLAIIAAEIVMSGIVGIGFFIWDAYQQNYVSDIILAVIYIGAVGLLLDRFVAWLQRWILRNM
What is the function of this protein?
Part of the ABC transporter complex CmpABCD involved in bicarbonate transport.  Probably responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Bicarbonate transport system permease protein CmpB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLME_SHESR
Sequence: MSGKKRTASSNRWMLEHFDDHYVKLAQKRGLRSRAAFKLEELQQKDQLIRPGMTVVDLGAAPGGWSQVAVKLAGDKGKVIACDILPMDPIVGVDFLQGDFREEKVLEALLTRVGADKVDVVLSDMAPNMSGSDGVDQPRAMYLVELALDMCHQVLAPNGSFAVKVFQGEGFDEYMKAVKEAFKVVKTRKPDSSRARSREVYLVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_PYRFU
Sequence: MLARRIIAALDIKDGRVVKGIKFKNIRDAGDPIELAKRYESEGIDEIVFLDITASYEKRKILLDLVERVAEEIYVPFTVGGGIRTVEEAREIIRRGADKIFINTAAVENPSLIKEIADLIGSANLVVAIDAKWNGKFWEVYTHGGRKPRGMDAVEWAKRVEELGAGEILLTSMDTDGTKQGFDIPLTKAVVDAVNIPVIASGGAGKPEHFLEVFRIGSDAALAASIFHYGEYTVRELKMFLAKNGIPVRLD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRO2_ARATH
Sequence: MAAQVEIEDQTSVTNLDNGEIFDSISDDADSSVSHAGSSFSSSSLILLGEGNPEHDVIKTCLLSGMGVVSSDTTIVTISKNSSERGITTRAKFLAFRIFTDAVARKHGGDANVKYGWYAGSRDEIQRIISYGFSNRDVGKFENDGGSHGIGIHLVPSKCSLLAASATEQDEEGLRYLLLCRVILGKPEIIISGSKQSYPSSAEFDSGVDDLHNPRNYVIWSCNMNSCILPSYIVSFRSPRLRVSRGGFASRPSSPWVSFASLMSMLSTSMDPSRMNLIIRTYDDFRKRKIRRDQLVRKMREVAGDNLLAEIIKNHKNRNKVTN
What is the function of this protein?
Probable inactive ADP-ribosyltransferase that may be involved in stress and developmental responses.
What are the official names of this protein?
Probable inactive poly [ADP-ribose] polymerase SRO2, Protein SIMILAR TO RCD ONE 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSAI_SACHY
Sequence: MTDLNLPSIFVPLVGLVFPAIAMTSLFLYVQKNKIV
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RNH2_ROSCS
Sequence: MMKGSPPTVEEERALCAVGYRAIAGIDEAGRGCWAGPVVAAAVILPERVIAKPELLDGVADSKMLTPAQRVALFERITSLAVAWAVGSVPAHVIDSHGILPATRLAMQVALLRLPLPADVLLIDAVRLDGWPLPQRVLVKGDVRCLSIAAASIIAKVMRDRFMEGLGRYWTRYGFAAHKGYGTAAHQEALRRYGPTPHHRLTFRPLCDMAPANIRNAALEGEQP
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_RHOPB
Sequence: MKLAIDCPDCRKMILALPRRAGRGAIWLYRHSLSPLVGYHCRHLPTCSSYGDEAIERFGLWAGGWMTLARLLRCQPWGTHGIDNVPLTAPAGARWYLPWRYARWRGVNG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LMF2_XENTR
Sequence: MGEQRLARSSFLWGLSGIYLVAFVSLYAQIPGLYGREGILPAWKMMRFTGKGFWEQLKDSPSLLWFGPRLGLDTEMTMEMICLLGALLSLGALLFSFLRDSLVFLLLWIFYLSLYQVGQVFLYFQWDSLLLETGFLAVLVAPVHALRWKTSVWSSHDGVTFWLTRWLLFRLMFASGIVKLTSRCPTWWGLTALTYHYETQCIPNPAAWFAHQLPVWFQKFSVVATYFIEIGVPLLFFLPFRRLRLFSFYSQVVLQILIIMTGNYNFFNLLTVVLCCSLLDDQHITFFQRHKKPQHKGGRVTSAFSLYSLISLLDVPIFGLLVFWTVKYFDLQINWEKHSVESRTAFTYHDFQQWLRTITFPTIWIAAASLGWEILKGMYRSASVRGIFWKLWSTLQWVIFSCAAVAMFTISLVPYTYIDFESNGHLWPEVHRMFNAVDRYQLVNSYGLFRRMTGVGGRPEVIVEGSYDRETWTEIEFMYKPGNISTTPSVIIPHQPRLDWQMWFAALAHNSHSPWFASFVYRLLQGNKDVIHLVQNDESLYPFHAYPPTYIRAQLYKYWFTEVDQSGQMPKSWWRRRHVEEFFPAVFLGDPFLDNLLTQHGLKDKPPARRSLDAPIPSALRLIRAFLHPLPAPLLLHSFIFGIFTIYFLQAMFGGVSKPGVAKQRHSKPPNEKKKQKSNSGQGESAAAKSSGHGADTVRRNKKNEKS
What is the function of this protein?
Involved in the maturation of specific proteins in the endoplasmic reticulum.
What are the official names of this protein?
Lipase maturation factor 2.
What is the protein family that this protein belongs to?
Belongs to the lipase maturation factor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AHPD_ANADF
Sequence: MSPVDRLREALPDAARDVRLNLQAVLQGGALTEGQRWGVAVASAAAARQPALLSAVLAEARSRGLDSAAEDGLAAAALMAMNNVYYRFRHMVGKPGYTEMPARLRMGRLAQPATSRADLELFSLAASAINGCEACVRTHEDVVVKGGIGEEAVHDAVRIAAVIHAAAVALEAGEVAGGHEAVSAA
What is the function of this protein?
Antioxidant protein with alkyl hydroperoxidase activity.  Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
What are the official names of this protein?
Alkyl hydroperoxide reductase AhpD, Alkylhydroperoxidase AhpD.
What is the protein family that this protein belongs to?
Belongs to the AhpD family.
Protein: BIOF_BURMS
Sequence: MNPLATLEQGLADIDAQGLRRCRRVADTACGAHMTVDGRAIIGFASNDYLGLAAHPRLVEAFAEGARRYGSGSGGSHLLGGHSRAHATLEDELAAFSGGFSDAPRALYFSTGYMANLAALTALAGRGATIFSDALNHASLIDGARLSRANVQIYPHGDADALDARLRACDAPTKLIVSDTVFSMDGDVAPLARLVALAETHGAWLVVDDAHGFGVLGPQGRGALAAHGLRSPNLVYVGTLGKAAGVAGAFVVAHETVIEWLVQRARSYIFTTAAPPSVACAVSASLAVIASDEGDARRAHLGALIKRTRAILRATHWQPVDSHTAVQPLVIGSNEATLAAMAALDAQGLWVPAIRPPTVPAGTSRLRISLSAAHSFDDLARLEAALVTPIGAAA
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: AIM20_YEAS1
Sequence: MGNASVAVGTAVGIPIAVGVIIALIFWCKLQRRYKKEEIRDADLEKMVMEEVAVSVYDGFKAEINSSSEASTINEKEANQDLKPCQEKTAKAGYTPAYRRQLNASMGTLRPKKQSTAYINVPVIFSGEKVNYGMVRDPSYSFMYPLTLSRKETSSLRSASTSNLSSSTENTALHEEIKLDDPYENDFTNYTVNKREFIDSLRPR
What is the function of this protein?
Involved in cell cycle progression and surviving DNA damage.
What are the official names of this protein?
Altered inheritance of mitochondria protein 20.
What is the protein family that this protein belongs to?
Belongs to the SKG1 family.
What are the subcellular locations of this protein?
Vacuole membrane; Single-pass membrane protein.
Protein: TRUB_PSEPG
Sequence: MAQVKRIRRNVSGIILLDKPLGFTSNAALQKVRWLLNAEKAGHTGSLDPLATGVLPLCFGEATKFSQYLLDSDKGYETVMQMGQTTNTGDAEGEVLQTRDVTVGRADIEALLPRFRGPISQIPPMYSALKRDGQPLYKLARAGEVVEREARSVTINRLELLECEGTRARLSVGCSKGTYIRTLVEDIGEALGCGAYVAELRRTQAGPFALAQTVTLEELEQAHADGGNEALDRFLMPSDSGLQDWPMVSLSEHSAFYWLHGQAVRAPDAPQFGMVRVQDHNARFIGIGEVSEDGRIAPRRLIRSE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CLCA_ECOLU
Sequence: MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGRMVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT
What is the function of this protein?
Proton-coupled chloride transporter.  Functions as antiport system and exchanges two chloride ions for 1 proton.  Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
H(+)/Cl(-) exchange transporter ClcA.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NQOR_GEOMG
Sequence: MKVLIPFYSMYGHIYRMAEAVAEGVREVSGAEAVLRRVPETLPTDVLQKMGAVEPQKAFAHIPVCTVDELAAADAIIFGTPTRFGNMCGQMRQFLDATGGLWVKGGLVGKAGGVFTSSATQHGGQESTILTFHTFLLHQGMVLVGLPYAFAGQMRIDEITGGSPYGASTIAGGQGERLPSENELAGARYQGKYIAEIAAKLKG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: HBB1_MURHE
Sequence: VEWSSNERSTITSLWGKINNAEIGQVALARVLIVYPWTQRYFGQFGDLSSIAAISGNPKVAAHGKVVLDGVEKAVKNLDSIKATYTKLSQLHSDTLNVDPDNFKLLGDCLTIVLSAKFGAEFTPAVQAVWQKFLSCVISALSRQYF
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-1, Beta-1-globin, Hemoglobin beta-1 chain, Hemoglobin beta-I chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: GID8_BOVIN
Sequence: MSYTEKPDEITKDEWMEKLNNLHVQRADMNRLIMNYLVTEGFKEAAEKFRMESGIEPSVDLETLDERIKIREMILKGQIQEAIALINSLHPELLDTNRYLYFHLQQQHLIELIRQRETEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDNPEDSPFGDLLNMMQRQKVWSEVNQAVLDYENRESTPKLAKLLKLLLWAQNELDQKKVKYPKMTDLSKGVIEEPK
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation.
What are the official names of this protein?
Glucose-induced degradation protein 8 homolog.
What is the protein family that this protein belongs to?
Belongs to the GID8 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the cytoplasm in the absence of Wnt stimulation and in the nucleus in the presence of Wnt stimulation.
Protein: RLME_METMA
Sequence: MARDRRDYYYHQAKEEGYRSRASFKLKQINEKHNVIKRGDSVVDLGAAPGGWLQVAKQLSGGKVLGVDLQRIDPIEGVETIQGDINAESTIKKIIKIVGEKGADVVLCDAAPNLSGNWSYDHARSIELATSALECAKKILKPKGNFAVKVFQGDMFNDYLDEVRNNFVRVKAYSPQASRSQSAEIYIIGKKFLTAPLRKGDKFVVDIEKLGSSGDGAVLIEGFVVFVKEVEVGEKVRIKISDVKPNFAFADVEERIESSETENREKSD
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA_STRGC
Sequence: MKKKIVAGAVTLLSVAVLAACGKTSGSDKDIITMKGDTITVSEFYDKVKSNPSAQQVLLNLTIKEVFEKQYGKKVTDKEVEEAYEKSSKAYGDNFARVLAQAGLTEDAYREQIRTNKLVEYAVKKAAEKELTDENYKAAYEAYTPEVTAQIIKVDSEDKAKEVLAAAKAEGADFAQLAKDNSTDGDTKDKGGEIKFDSAATNVPDAVKKAAFGLEANAVSDLVTVRSNQGQASYYIVKLVSKTEKSSKWEDYKDKLKQVILTAKQNNTSFIQSVVAKELKDANIKVKDAAFQNLFSQYTQTNTSSSSSK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HOX3_XENLA
Sequence: MEGRKEMLMYLEGGQLGTLVGKRMAHLSDAVGSPMAESQDKLVPKSPRAGPIAPTDRAEESEVEVGQATGQQRSRSPQLRISSPHPPAHSDSLSTKGQHSSSDTESDFYEEIEVSCTPDCNSAASDYQQHSAGQCSEPMGGSPVNGSDSSKGGGGSHGSFSACAGDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAATGNLPYPFPSHLPLPYYSHMGISAGSTAAATPFSAPLRPLDTFRVLSHPYPRPDLLCAFRHPSIYASPAHGLGSGGSPCSCLACLSTSTNGLGQRAAASDFTCSSTSRSDSFLTFTPSILSKSSSVSLDQREEVPLTR
What is the function of this protein?
May be required for posterior development and development of normal embryonic axial pattern.
What are the official names of this protein?
Homeobox protein XHOX-3.
What is the protein family that this protein belongs to?
Belongs to the even-skipped homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MYLKD_DICDI
Sequence: MPIGDYELHKEIGKGAFSVVFLVTEKKTKKQWAMKIIDKKSSSKAALETEIEIMKKVDHPNIVKMHEYFESTDKIYLVVELVTGGPLFDRIVDKKSFTEKEAKLITQQLLQSLVYLHSIGIVHRDLKPENLLLKTPTDLTVALSDFGLSKIVGDDVFMKTTCGTPSYVAPEVLNNISNSPTAYSDAVDMWGVGVITYILLCGFPPFYSEDIRKLFESILSASYDFPNDYWGNVSKEAKHFINCLLTVEPTKRYSAKQALEHPWIIENNQTQPLPHWNDQIKKYMVIRRKESQKFGAELVWKPQAQTTNVKPTK
What is the function of this protein?
May phosphorylate a specific serine in the N-terminus of a myosin light chain.
What are the official names of this protein?
Probable myosin light chain kinase DDB_G0292624.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: THA11_MOUSE
Sequence: MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRLCSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQLQQQQPSPSSSTAQTTQLQPNLVSASAAVLLTLQAAVDSNQAPGSVVPVSTTPSGDDVKPIDLTVQVEFAAAEGAAAAAAASELEAATAGLEAAECTLGPQLVVVGEEGFPDTGSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELREKDRLLAMAVIRKKHGM
What is the function of this protein?
Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells.  Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.
What are the official names of this protein?
THAP domain-containing protein 11, Ronin.
What is the protein family that this protein belongs to?
Belongs to the THAP11 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May be regulated by shuttling of the protein between the cytoplasm and nucleus.
Protein: IDI2_BACC2
Sequence: MVRAKRKLDHIEYALSTGQSRTHGFHDIDFVHQSLPNSNYDTITCETKIGELSLSSPIFINAMTGGGGEKTLHINEQLAYVAKQHNLAMAVGSQMAALKDESEAASYKVIRKVNPNGIFFANLGSEATIEQAERAVDMIEANALQIHLNVIQELTMPEGDRDFTGVLQRIEKIVLNSKVPVIVKEVGFGMSKETMQQLANVGVTAIDIGGQGGTNFAAVENERRQRMLSYFNNWGIQTATSIIEATSTNNNLSFIASGGIQTALDVAKAIALGANTTAFAGYFLRILMQDGIEKLVDEIELLHTDLKFIMTALGAKTIEELQSVPLVVKGETYHWLMQRGIDTAHYSRR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP25_TRIVH
Sequence: MSGIALQGFRCHACRNAAFRSFAAISSLSSSTRRPQSSISYPGSKLYQRNVRTTGRRQFSALGSVQSQADSDLPTKTETKEDTSAESSHIPWYLQDESHKPSSHPLKQQELPPLPENPPPILENLLQYISVDAGLDDLALLDLRGLDPPPALGANLIMIIGTARSVKHLNVSGDRLCRWLRSNYQLRPVADGLLGRNDLKIKLRRRARKAKVTGDASSLNSRDDGITTGWICVNVGDVENGPLKTKNSRNRNFIGFGGTEDKVRIVVQMLVEETRSELQLEALWGSLLNPEAGEMNPAPRDDVWGDLSSETTSSGKGVDSIASTFSQRFPGRRHIHTQARPNTPEPLSHETLGDIVQESRPALPSKIVSTSMASPNVSSLLEQLSRLPEEEARRELGLGPGDRDSTLFLRLFYEAVSKSDTETVLIDKLSFARAAVLLKHPAYRKADLYRAFKSMAASGCSISEELAMDTVRTLLSFQGPENAANERVPEQDIDLALRVLEHMSLRGINIFNGEVFFLLHKASAFQSHVPANDAPGAMNTSVNPDSVSKVQVEELDRITTVHNRLSKLMASANVDFDYKDYPELLKMYFEHGNYSNFWRLWHRIPLMQIPRTKELYLLMFRLHAKLGHQRQAVDCLSSWVPMMAREQPPVALDEELTRAIMACMLVADPAIDQKTDDGTVSQFTRLWKQCLRDLESFKAANSQ
What is the function of this protein?
Probable mitochondrial mRNA stabilization factor.
What are the official names of this protein?
ATPase synthesis protein 25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATP25 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RUP1_YEAST
Sequence: MMDNQAVKSLLEMGIPHEVAVDALQRTGGNLEAAVNFIFSNELPEQAEMGEENDGSQPRISENKIVAGTKPCDVPNNGDQDIDMPDVSGVDVDYDDDEDITDERSGSNSTSGCRVTAQNYDRYSISETSIPPPSYSIVQHNEFKSNVGDPTVVLPLPLNSLIESYFGLFALLTAVYFPHVFLKPDFKDLNYRADWFKGSSFTEPKYRLAYCEAEDGSTTSEIVLASGPNEGLQPHLLWQLQKLISVVNTRKCERAFVSAKVFTSSLEPQLRSKLADSEHLYEVLPAFIKSLAVDLEMCPGIRDRETRSLFISSALHTPNKNEPPMETFLSLFHFLPEEYDSNLYKMFNVLLYPEEEEEEEDVIRGGEQEEARYVEPENTLKEVAPVLTILFNELETNTESVSLPNGVDIPLEFYPQLYTKQCKDQLIRHIISKRKQARTRSRCLLQEINELKSYQGKNISTILESTLAYLQTIPDDANNEAAKQIASLKDTLNSARAAKMEEYKDLASKLHGEWNLSHPETHIINTAKQLGLIENPYILTMAALSPYSYFIRSRNGAWSWIQSNTLGTEFKVKKCSSPSVVQEAIKHGTKYASETPLMFIYCEEGKIPTEEVVAEALKSNSGCLKFAEDDQNSLKTLRSQFFDGMGDPEQATNNINNGNDNDNDDDIDSDN
What is the function of this protein?
Modulates the activity of the RSP5 HECT ubiquitin-protein ligase through its mediation of the interaction between RSP5 and the deubiquitinase UBP2.  Involved in regulation of cell wall homeostasis.
What are the official names of this protein?
UBA domain-containing protein RUP1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YNO4_YEAST
Sequence: MSSSIFEMTIDHDGMDSTGLKLSQTASSISMGDEFLCSSTTSNSILDSPLPKVTFNHIDSITDINTNIMNEIVEPQSGVDVDVADKNVLYCIDPYPVEPPCYDFANPSKVIRYPIYEHCRPCLTSVKPPSYTPSVEHYTVVSMKMEKLSPFENASSRLWNNFILQINSTQINFYSIDDSLTRHIKNYRGGDMFDHSHHSKTASDRHHSARSLLNAFTTKSTYQFDKYDKERICGEIARDEHKFLSDERLFKSYSLQCAKVGLPIDYSSRDFVLRMRCEGQQFLVQFSHVDELIYWAMYLNMGISLSLDLELREMPTYRSVPRRRHPRARRFKQHNKNKNKNKSRQNSDRNDSRSHSLLLRRSHTSSVVTKVATGNERPTNKSRSRSLSLLPPSVSDASHDSNGPNDSGSLAGESSQTDFCGLFTSKLRNFFKTDSSSRKNSNMDIGQKMRSKELNSVQEEIDDNGSTTNTNTSVLSSTFSPTAHSVLTAQTSIHENFRSRSNSNPIDPLRCDRSVLKINNFEPVYEGTGRSTISNSAERTNREEKLNRGNEDVNGDEDDDEDEDDANYEEDDEDGYVEDDDINRLVYLDERESRYENADVEYGTIFSTKSFSVTGCLNHDFPKKLSLKCGNKNQSSNDSKWAPATQLVSRKRYIKDSLRCIKPLTEDHPWVGKIIFKPALPPAFETNNPPIRVYSGEDSTDLMHVKNHYLKPYIVGSCGFLKTGSKLFHFYDRTNDLTNL
What are the official names of this protein?
Uncharacterized protein YNL144C.
What is the protein family that this protein belongs to?
To yeast YHR131c.
Protein: IKBL_ASFP4
Sequence: MEHMFPENQIENLFVGWIKKHIRNGDLTLFEEFFKTDPWIVNRCDKNGSSVFMWICIYGRIDFLKFLFKQESYPGEIINHHRRDNDGNSALHYLAEKKNHLILEEVLGYFGKNGTRICLPNFNGMTPVMKAAMRGRTLNMLSLIKFGADPTQKDYHRGFTAWDWAVFTGNMELVKSLNHDYQKPLYMHFPLYKLDVFHRWFKKKPKIIITGCKNNVYEKLPEQNPNFLCVKKLNKYGK
What is the function of this protein?
IkB-like protein that inhibits the binding of NF-kappa-B to DNA, thereby downregulating pro-inflammatory cytokine production (By similarity).  Forms a heterodimer with the NF-kappa-B subunit RELA/p65 and prevents the activation of the NF-kappa-B transcription factor (By similarity).  Inhibits calcineurin function, which is required for the induction of nuclear factor of activated T cells (NFAT)-dependent immune response genes.  Prevents the binding of substrates to calcineurin without affecting the phosphatase activity (By similarity).  Does not contain the serine residues that are phosphorylated by host IkB kinase and thus is not degraded following stimulation of the NFkB pathway (By similarity).
What are the official names of this protein?
IkB-like protein, Ankyrin repeat domain-containing protein A238L, p28.
What is the protein family that this protein belongs to?
Belongs to the asfivirus A238L family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Binding to host PPP3CA/Calcineurin may mask the second nuclear localization signal thereby contributing to the cytoplasmic retention of A238L.