PharMolix/UniProtQA huggingface dataset:
Protein: BUR1_CANGA
Sequence: MSQENSNVPALKRTESKYKIGRVKSLPTVQIDEKTGDSYIELAPRSEGKIYGCTTFQGNYKEEEKLGQGTFGEVYKGLHLQTQRKVAMKRIIVNQENDLFPITAQREITILKRLNHKNIIKLLEMVYDFPPESNNKDYAQFNQNNSANPPAVPKKFFYMILPYMVADLSGILHNPRIELKMADIKNMMKQILEGVNFIHCSKFMHRDIKTANLLIDHNGVLKLADFGLARQYYGSPPNIKFPGSAGSGAKYTSVVVTRWYRAPELVLGDKYYTTAVDIWGVGCVFAEFFEKKPILQGKTDIDQGHVIFKLMGTPDERTWELAKYLPGAELTKTEYKSTIDERFGKHLTPTGLSFLKGLLALDPYKRLTAMSAMKHPFFQEEPLAADRLTLPCEESHEADIKRYKEELHEAMSQKGPSAPPGHIKEATPSPAKFEKKSGIKREQPYQSNQKNDQYPIKRQKFNQNPSVPHPQPKANRYGGSSLPSGPKYGRYEGNNHSGSLRNRITPSNMGTHSNPRAENMGSKPYQSEGRYSSNEDRKNGYNRGYSSSVNSRYNNRAAFNETEDQSITTTTLNRYRHKGYHDNNQSQTRLQGHSSLPGKPTSKYNSTQTNIPYRRTEIPNPNEYNASKLGSQDTKKNDYPKHSETQKQQNNEEKKIHSEQKDIADLY
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation.  Phosphorylates the UBC2/RAD6 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes.  Also required for histone H3 methylation.  Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase BUR1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MTLD_STRPJ
Sequence: MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEKGKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELLAKGIEARRVAGNTQALDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAVDRIVPTQSHEDSLFVMVEPFNEWVVETKRLKNPDLRLEDVHYEEDLEPFIERKLFSVNSGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHKVIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFDYRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIERIVEYI
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: GPR18_HUMAN
Sequence: MITLNNQDQPVPFNSSHPDEYKIAALVFYSCIFIIGLFVNITALWVFSCTTKKRTTVTIYMMNVALVDLIFIMTLPFRMFYYAKDEWPFGEYFCQILGALTVFYPSIALWLLAFISADRYMAIVQPKYAKELKNTCKAVLACVGVWIMTLTTTTPLLLLYKDPDKDSTPATCLKISDIIYLKAVNVLNLTRLTFFFLIPLFIMIGCYLVIIHNLLHGRTSKLKPKVKEKSIRIIITLLVQVLVCFMPFHICFAFLMLGTGENSYNPWGAFTTFLMNLSTCLDVILYYIVSKQFQARVISVMLYRNYLRSMRRKSFRSGSLRSLSNINSEML
What is the function of this protein?
Receptor for endocannabinoid N-arachidonyl glycine (NAGly) (PubMed:16844083, PubMed:24762058, PubMed:27572937).  However, conflicting results about the role of NAGly as an agonist are reported (PubMed:27018161).  Can also be activated by plant-derived and synthetic cannabinoid agonists (PubMed:24762058).  The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase (PubMed:16844083).  May contribute to regulation of the immune system.  Is required for normal homeostasis of CD8+ subsets of intraepithelial lymphocytes (IELs) (CD8alphaalpha and CD8alphabeta IELs)in small intstine by supporting preferential migration of CD8alphaalpha T-cells to intraepithelial compartment over lamina propria compartment, and by mediating their reconstitution into small intestine after bone marrow transplant (By similarity).  Plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure (By similarity).  Mediates NAGly-induced process of reorganization of actin filaments and induction of acrosomal exocytosis (PubMed:27572937).
What are the official names of this protein?
N-arachidonyl glycine receptor, NAGly receptor, G-protein coupled receptor 18.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Protein: VATA_PIG
Sequence: MDFSKLPKILDEDKESTFGYVHGVSGPVVTACDMAGAAMYELVRVGHSELVGEIIRLEGDMATIQVYEETSGVSVGDPVLRTGKPLSVELGPGIMGAIFDGIQRPLSDISSQTQSIYIPRGVNVSALSRDVKWEFTPSKNLRVGSHITGGDIYGIVNENSLIKHRIMLPPRNRGTVTYIAPPGNYDTSDVVLELEFEGVKEKFSMVQVWPVRQVRPVTEKLPANHPLLTGQRVLDALFPCVQGGTTAIPGAFGCGKTVISQSLSKYSNSDVIIYVGCGERVNEMSEVLRDFPELTMEVDGKVESIMKRTALVANTSNMPVAAREASIYTGITLSEYFRDMGYHVSMMANSTSRWAEALREISGRLAEMPADSGYPAYLGARLASFYERAGRVKCLGNPEREGSVTIVGAVSPPGGDFSDPVTSATLGIVQVFWGLDKKLAQRKHFPSVNWLISYSKYMRALDEYYDKHFTEFVPLRTKAKEILQEEEDLAEIVQLVGKASLAETDKITLEVAKLIKDDFLQQNGYTPYDRFCPFYKTVGMLSNMIAFYDLARRAVETTAQSDNKITWSIIREHMGEILYKLSSMKFKDPVKDGEAKIKADYAQLLEDVQNAFRSLED
What is the function of this protein?
Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity).  May play a role in neurite development and synaptic connectivity (By similarity).
What are the official names of this protein?
V-type proton ATPase catalytic subunit A, V-ATPase subunit A, V-ATPase 69 kDa subunit, Vacuolar proton pump subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein. Lysosome. Note=Co-localizes with WFS1 in the secretory granules in neuroblastoma cell lines.
Protein: RS201_ARATH
Sequence: MATAYQPMKPGKAGLEEPLEQIHKIRITLSSKNVKNLEKVCTDLVRGAKDKRLRVKGPVRMPTKVLKITTRKAPCGEGTNTWDRFELRVHKRVIDLFSSPDVVKQITSITIEPGVEVEVTIADS
What are the official names of this protein?
40S ribosomal protein S20-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: UPKL2_HUMAN
Sequence: MDNSWRLGPAIGLSAGQSQLLVSLLLLLTRVQPGTDVAAPEHISYVPQLSNDTLAGRLTLSTFTLEQPLGQFSSHNISDLDTIWLVVALSNATQSFTAPRTNQDIPAPANFSQRGYYLTLRANRVLYQTRGQLHVLRVGNDTHCQPTKIGCNHPLPGPGPYRVKFLVMNDEGPVAETKWSSDTRLQQAQALRAVPGPQSPGTVVIIAILSILLAVLLTVLLAVLIYTCFNSCRSTSLSGPEEAGSVRRYTTHLAFSTPAEGAS
What are the official names of this protein?
Uroplakin-3b-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the uroplakin-3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: STUM_DROME
Sequence: MQQTLSYSSSSPSPSPMPMPSASAAQTPPPNPNLTPNLNIRPSTNPIPRPRSTGGESAFQPAIIPVDYSYRTHTTRSILSAQSMAPSTFASNQSFVRQPSESDAQPYSSLFGDPVPPPLQPDDYFGTAAFETLRNGSVELPSSEEDALVAAMALNALIPAARERIFPSVPYSRTPRGSLLPYLQPPDIQILPNSSGGSSSEQLGSPNYRLLAPDDILNKPDVYDLENEVEEYTVVGQRMSFDDEEDEPTRTPSQAPAKLSVSSITTEDHRGLLSDSYSGRDWFRPAPQHFPEFTRIPRLRPSSKMIMSMKQDEGPLSPLATMIQDMNSSSSGGEERVAPNQSRPVSRDVVLSPKQYLEEQLGLERGSQRQSLEDYRMPPPPADPPPFRRTDLTEQDDSRSVEPEHSLKREMSPVIIRDSIPMGGDYRVEQPRPHKKTAFTILSTGQAASSAPRPPQQAPTRGRHASIQSTSTTTSSPAGRPQISPRRRSIFGSEPRLPELPSALGYTSHLVHQTTDDSPRPSVQFNMSGRHSRSKLAIPQKGILQQRDSLTSSIDTFTPRAQIRRGSIGRDPIRSLPYGQKIKSMETLPLINDQHRSSIPRLHYGSTMDLSRPEPAVFPPGALPRPLKPNLNPTRRQRGLLKIINKEESLTHNPPRSNWCSLDDLSRPSFDGTPNQARRRSSSTSPERRSSTQTVSDRRSSNLSSVTATTSDFSFRRPTLSTLPAAQTLSRMRRKSVQALSPNRIPNRIPSFGQRRQSIYQRDQEPKPLSRHGKIAKPSTLSPIIGTPNKDSSSAQSPNHRSSLMADAVDTPSEVSTRRDSVSRIPVRKSPDSRSSSPPKDFGIPASGRSSRASITRSPSRTMNAGSRSPSRSMHPSRTSSRESGRPGDSRSASRGPPSRPGSRLDQIGSRMDRPNSRLERSSSRAERSSSRADRPSSRFDVSNSRGNSRANSRLSINSSSLRSSSISPATMARNRSMRATTPSRRKSISLSPASAMMGRRKSISPDAVGQNRRVSSRGKPEPPEILSRRNSRSRIPTRSTKVASKSPPSSSKKRSKSPEKPKAMGSTPKSNKVGKGVTAKGSPKAKPKIAASAKPKTKTESLMKPPVKNANKTPVNGRPTTNAKKPASKAISTKDAKVEKGKETGKSVASKSNGKETESSVKSSKSQVTKTKPPGGTTSEAKKPATTKTHGITLEKGTNGTDPVGGIPPLAAQVGNAVLQAVEAVPAVTSEVTVPSTPGGKGAGGANMSKLVRMSSRMSLLSNKSTKVRSDSPQNRKVATVQEHATEKEETVGASSQPMSNDAAAILEKSQKTLENIQKTVTEATDEIHKTISENLTDLKSLENDLAADPSPTPSSGTTMARPGESASRTGTADGSIAPQSSGELPKSPFPPTQPIEASVSVLHPNESSAERIASVPEVECESSDLPTALDASESELVGNVMPTPESGADFKVDAKRRSPDGQGGSTAGSGGLAKSSSQEFLEDKDNVKKGGLCGCCSKLFMPCRRSRCSRCCRRRERNESAEDQPVLWSGNSSATTATNVQVIDETKPKRKKISDWLKSSCCRSCRKKPAIEEHEAHQEEVSKRTNQAANMSTGPRTRGKCGLCLSKVFCCRSVNRVDPTTGDETEMKQCCFCIPCRRGSRPNKKGSTVSWRDQDPELGIKPTESSVVEGASEAAMSAATDAGNDQVKEGCCKRFWLMLLCCRKRKRRESNARRQSIRAPPPSEDTRKKLHVDLVEYSSKMKGAIPVLPLYLAWFCAFCNVVFPGLGTLLSGLFCLCVGIPRFSQFDSARARIGSFIINIIVAVSQFFCVLFCFVGWGWSIWWGTIMLRCAKKLSKIKKVERLELEEEQRQAQLAEAGKNGVAEADKT
What is the function of this protein?
Required for locomotion and mechanical sensing in proprioceptive neurons by transducing dendrite stretching into cellular responses.  Required for transduction of mechanical stimuli in a specific subpopulation of proprioceptive neurons that sense joint angles.  Probably does not constitute the mechanically activated channel and may rather serve as an accessory module required for the proper localization or function of the transduction channels.
What are the official names of this protein?
Protein stum.
What is the protein family that this protein belongs to?
Belongs to the SPEC3 family. Stum subfamily.
What are the subcellular locations of this protein?
Cell projection, dendrite. Membrane; Multi-pass membrane protein. Note=Specifically localizes to the distal part of the sensory dendrite. Does not accumulate in any other part of the cell.
Protein: PFKA_YERPE
Sequence: MVKKIGVLTSGGDAPGMNAAIRGVVRAALSAGLDVFGIEDGYLGLYENRMKKLDRYSVSDMINRGGTFLGSARFPEFRDPEVRKVALKNMHERGIDGLVVIGGDGSYAGADLLTKEGGIHCVGLPGTIDNDVAGTDYTIGFFTALETVVEAIDRLRDTSSSHQRISIVEVMGRYCGDLTLAAAIAGGCEFIAIPEVEFKRDDLVAEIKAGIAKGKKHAIVAITEKLDDIDSLAKYIEKETGRETRGTVLGHIQRGGAPVAYDRILASRMGAYAVDLLLQDHDYKKGGFCVGVQNEKMVHELISVCIAPENKKSKFKEDWYDTAKKLF
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OAMB_DROME
Sequence: MNETECEDLIKSVKWTEPANLISLAVLEFINVLVIGGNCLVIAAVFCSNKLRSVTNFFIVNLAVADLLVGLAVLPFSATWEVFKVWIFGDLWCRIWLAVDVWMCTASILNLCAISLDRYVAVTRPVTYPSIMSTKKAKSLIAGIWVLSFFICFPPLVGWKDQKAVIQPTYPKGNHTLYYTTTMSSSEDGQLGLDSIKDQGEASLPPSPPHIGNGNAYNPYDPGFAPIDGSAEIRIAAIDSTSTSTTATTTTTASSSSTTETEMDLDLLNAPPQNRPQTISGSCPWKCELTNDRGYVLYSALGSFYIPMFVMLFFYWRIYRAAVRTTRAINQGFKTTKGSKGIGSRFEEQRLTLRIHRGRGSNQQDSMHSNGSTQSTTTTLGTPSPERLSKYATRRLHHHDKIKISVSYPSSENISELAGHGDVGHERRQSGNALFAVHYNGTNGRESTESQLYRQQQQHGVASSCYLQVGKGLPELARRQSNTSEAGGSGHSRPANKKMGRRNIKAQVKRFRMETKAAKTLAIIVGMFIFCWCPFFTMYIIRPFCQDCVDPLLFSVLFWLGYCNSAVNPMIYALFSKDFRFAFKRIICRCFCSRQSVSLKSSRRGSDMSAIRIRARTPSITPSAAAHSFGDESELHHSEMSNDPR
What is the function of this protein?
Receptor for octopamine (OA) which is a neurotransmitter, neurohormone and neuromodulator in invertebrates (PubMed:9570796, PubMed:15816867).  Stimulates intracellular accumulation of cAMP and Ca(2+) following ligand binding (PubMed:9570796, PubMed:15816867).  Required for ovulation (PubMed:14623240, PubMed:19262750).  Following activation on mature follicle cells by OA, induces activity of the metalloprotease Mmp2 which leads to breakdown of the posterior follicle wall, resulting in ovulation (PubMed:26473732).  Ligand binding probably also leads to activation of CamKII which is also required for ovulation (PubMed:19262750).  Modulates sleep/wake behavior by acting in neurons of the pars intercerebralis to promote wakefulness (PubMed:20223202).  Plays a role in courtship conditioning where the courtship behavior of males rejected by already mated females is inhibited with further females (PubMed:23055498).  Required in the mushroom body for appetitive olfactory learning (PubMed:23103875, PubMed:23345239).  Specifically conveys the short-term reinforcing effects of sweet taste (PubMed:23103875, PubMed:25728694).  In insulin-producing cells of the brain, plays a role in inhibiting transcription of insulin-like peptide Ilp3 (PubMed:24923784).  Also plays a role in social behavior by modulating male agression (PubMed:24923784).
What are the official names of this protein?
Octopamine receptor Oamb, Octopamine receptor in mushroom bodies.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCDA7_MOUSE
Sequence: MVNLRGYNWKSQQLLLFLIIVAAWEAGSGQLHYSVPEEAKHGTFVGRIAQDLGLELTELVPRLFRVASKDRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDINDNPPMFPATQKALFILESRLLDSRFPLEGASDADVGSNALLTYRLSTNEHFSLDVPPNHEQVKPLGLVLRKPLDREEAAEIRLLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRSLYTVKLPENVPNGTLVIKVNASDLDEGVNGDVMYSFSSDVSSDIKSKFHMDTVSGEITVIGIIDFEESKAYKIPLEARDKGFPQLPGHCTILVEVVDANDNAPQLTVSSLSLPVSEDSQPGRVVTLISVFDRDSGANGQVTCSLTPHIPFKLVSTFKNYYSLVLDSALDRETIANYDVIVTARDGGSPSLWATASVSVEVADVNDNAPLFAQPEYTVFVKENNPPGAHIFTVSAMDADAQENALVSYSLVERRVGERLLSSYVSVHAESGKVFALQPLDHEELELLQFQVSARDAGVPALGSNVTLQVFVLDENDNAPTLLGPLANGVGGTMNEVVSRALVPGQVVAKVRAVDEDSGYNAWLSFELQPVAGGVRSPFRVGLYTGEISTTRALEETDALRQCLLVLVKDHGEPSLTATATVLLSLVDSGQTQKVSSKVSAGASRVDQRLVDVNVYLIIAICAVSSLLVLTLLLYTALRCSATPTDGACAPGKPMLVCSSAVGSWSYSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPANNQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
What is the function of this protein?
Calcium-dependent cell-adhesion protein involved in cells self-recognition and non-self discrimination (PubMed:27161523).  Thereby, it is involved in the establishment and maintenance of specific neuronal connections in the brain (PubMed:27161523).
What are the official names of this protein?
Protocadherin alpha-7, PCDH-alpha-7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: METK_HAEIG
Sequence: MSSYLFTSESVSEGHPDKIADQISDAVLDEILKQDPKARVACETYVKTGMALVGGEITTSAWVDIENLTRKVICDIGYEHSEMGFDGHSCAVLNAIGKQSADINQGVDRENPLDQGAGDQGIMFGYATNETDVLMPAAITYAHRLMEKQAEVRKSGKLAWLRPDAKSQVTLKYEDNKIVGVDAVVLSTQHSEEVSQKDLHEGVMEEIIKPVLPSEWLSKETKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQLSYAIGVADPTSIMVETFGTGKVANELLVSLVREFFDLRPYGLIKMLDLIQPIYRETAAYGHFGREQFPWEKVDRAEDLRVAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: M21_TRTV
Sequence: MSRRNPCRYEIRGKCNRGSSCTFNHNYWSWPDHVLLVRANYMLNQLLRNTDRTDGLSLISGAGREDRTQDFVLGSANVVQNYIEGNTTITKSAACYSLYNIIKQLQENDVKTSRDSMLEDPKHVALHNLILSYVDMSKNPASLINSLKRLPREKLKKLAKIILQLSAGPESDNANGNTLQKGDSNN
What is the function of this protein?
Essential for viral replication in vivo (By similarity).  Plays a role in the association of the matrix protein with the nucleocapsid, which initiates assembly and budding (By similarity).
What are the official names of this protein?
Protein M2-1, Envelope-associated 22 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the pneumoviridae M2-1 protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Note=Localizes in cytoplasmic inclusion bodies substructures called inclusion bodies associated granules (IBAGs). Forms a layer between the matrix and nucleocapsid.
Protein: PME21_SOLLC
Sequence: MATPQQPLLTKTHKQNSIISFKILTFVVTLFVALFLVVFLVAPYQFEIKHSNLCKTAQDSQLCLSYVSDLISNEIVTSDSDGLSILKKFLVYSVHQMNNAIPVVRKIKNQINDIREQGALTDCLELLDLSVDLVCDSIAAIDKRSRSEHANAQSWLSGVLTNHVTCLDELDSFTKAMINGTNLDELISRAKVALAMLASVTTPNDEVLRPGLGKMPSWVSSRDRKLMESSGKDIGANAVVAKDGTGKYRTLAEAVAAAPDKSKTRYVIYVKRGTYKENVEVSSRKMNLMIIGDGMYATIITGSLNVVDGSTTFHSATLAAVGKGFILQDICIQNTAGPAKHQAVALRVGADKSVINRCRIDAYQDTLYAHSQRQFYRDSYVTGTIDFIFGNAAVVFQKCQLVARKPGKYQQNMVTAQGRTDPNQATGTSIQFCDIIASPDLKPVVKEFPTYLGRPWKKYSRTVVMESYLGGLIDPSGWAEWHGDFALKTLYYGEFMNNGPGAGTSKRVKWPGYHVITDPAEAMSFTVAKLIQGGSWLRSTDVAYVDGLYD
What is the function of this protein?
Pectinesterase may play a role in cell wall metabolism during fruit growth and development prior to ripening and may be required for preparing cell walls for softening by polygalacturonase during fruit ripening.
What are the official names of this protein?
Pectinesterase 2.1, PE 2.1, Pectin methylesterase 2.1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: CRCB1_ALKCK
Sequence: MKLVYTYVAVALGGALGGAFRFILTIIFPFHNWPWGIFTANLGGCFLLGFLTPILQLKKSIPLAVKKGITVGLIGGFTTMSTFAADTIAMLQNGHLLGGSVYLLATVTGGMGFVALGFVLGARGRTR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RDRP_TMGMV
Sequence: MAHIQSIISNALLESVSGKNTLVNDLARRRMYDTAVEEFNARDRRPKVNFSKTISEEQTLLVSNAYPEFQITFYNTQNAVHSLAGGLRALELEYLMLQVPYGSPTYDIGGNFAAHLFKGRDYVHCCMPNLDIRDIMRHEGQKDSIEMYLSRLSRSNKVIPEFQREAFNRYAEAPNEVCCSKTFQDCRIHPPENSGRRYAVALHSLYDIPVHEFGAALISKNIHVCYAASILAEALLLDQTEVTLNEIGATFKREGDDVSFFFADESTLNYSHKYKNILHYVVKSYFPASSRIVYFKEFLVTRVNTWFCKFTKVDTYILYKSVRQVGCDSDQFYEAMEDAFAYKKTLAMFNTERAIFRDTASVNFWFPKMKDMVIVPLFEGSITSKKMTRSEVIVNRDFVYTVLNHIRTYQAKALTYQNVLSFVESIRSRVIINGVTARSEWDVDKAILQPLSMTFFLQTKLAALQDDIVMGKFRCLDKTTSELIWDEVGKFFGNVFPTIKERLVSRKILDVSENALKIKIPDLYVTWKDRFVAEYTKSEELPHLDIKKDLEEAEQMYDALSELSILKGADNFDIAKFKDMCKALDVSPDVAARVIVAVAENRSGLTLTFDKPTEENVAKALKSTASEAVVCLEPTSEEVNVNKFSIAEKGRLPVCAESHGLTNANLEHQELESLNDFHKACVDSVITKQMASVVYTGSLKVQQMKNYVDSLAASLSATVSNLCKSLKDEVGYDSDSREKVGVWDVTLKKWLLKPAAKGHSWGVVLDYKGKMFTALLSYEGDRMVTESDWRRVAVSSDTMVYSDIAKLQNLRKTMRDGEPHEPTAKMVLVDGVPGCGKYKGDFERFDLDEDLILVPGKQAAAMIRRRANSSGLIRATMDNVRTVDSLLMHPKPRSHKRLFIDEGLMLHTGCVNFLVLISGCDIAYIYGDTQQIPFINRVQNFPYPKHFEKLQVDEVEMRRTTLRCPGDVNFFLQSKYEGAVTTTSTVQRSVSSEMIGGKGVLNSVSKPLKGKIVTFTQADKFELEEKGYKNVNTVHEIQGETFEDVSLVRLTATPLTLISKSSPHVLVALTRHTKSFKYYTVVLDPLVQIISDLSSLSSFLLEMYMVEAGSRXQLQMDAVFKGHNLFVATPKSGDFPDLQFYYDVCLPGNSTILNKYDAVTMRLRDNSLNVKDCVLDFSKSIPMPKEVKPCLEPVLRTAAEPPRAAGLLENLVAMIKRNFNAPDLTGTIDIESTASVVVDKFFDSYFIKKEKYTKNIAGVMTKDSMMRWLENRKEVLLDDLANYNFTDLPAIDQYKHMIKAQPKQKLDLSIQNEYPALQTIVYHSKQINGILAGFSELTRLLLEAFDSKKFLFFTRKTPEQIQEFFSDLDSHVPMDVLELDISKYDKSQNEFHCAVEYEIWKRLGLNEFLAEVWKQGHRKTTLKDYIAGIKTCLWYQRKSGDVTTFIGNTVIIAACLGSMLPMEKVIKGAFCGDDSVLYFPKGLDFPDIQSCANLMWNFEAKLYRKRYGYFCGRYIIHHDKGAIVYYDPLKLISKLGAKHIKDYDHLEELRVSLCDVACSLGNWCLGFPQLNAAIKEVHKTAIDGSFAFNCVNKFLCDKFLFRTLFLNGC
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities (Potential).  It also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May mediate silencing suppression through either inhibition of HEN1-mediated siRNA or siRNA demethylation (By similarity).
What are the official names of this protein?
Replicase large subunit, 183 kDa protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: RS181_STRAW
Sequence: MAKPPVRKPKKKVCAFCKDKVTYVDYKDTNMLRKFISDRGKIRARRVTGNCTQHQRDVATAVKNSREMALLPYTSTAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: Y025_HIS1I
Sequence: MAGIHVVLGLFEGALFTNVNAFLVLMIILSGLIGLFSGYASIGAFGSFVSFTHIASTVDLWIFNSMLYIIMTIVFVVMSLQAWQFIGSNGVNQ
What are the official names of this protein?
Putative transmembrane protein ORF25.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: Y1557_ARCFU
Sequence: MSERDILIERLERKLAEKERELVELRRMNREELEKIKREIAMEAKEEVLREVHKLLQNSQIQRLSEVDSKIVELRKAMESIITELAYIKGELKGLQEKGESKVERKEIIEEKIQKAMVFENEPLYLEEKEERKPAKESKRREHDVIIPEGKKEERTDDGEDGLIVCD
What are the official names of this protein?
Uncharacterized protein AF_1557.
Protein: RL40_SACS2
Sequence: MPLTDPAKLQIVQQRVFLKKVCRKCGALNPIRATKCRRCHSTNLRLKKKELPTKKG
What are the official names of this protein?
50S ribosomal protein L40e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL40 family.
Protein: RS15_STAAB
Sequence: MAISQERKNEIIKEYRVHETDTGSPEVQIAVLTAEINAVNEHLRTHKKDHHSRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: UMAS1_HUMAN
Sequence: MAWGLPCHQNTAGANPHLFLGCYSTSSLQGLEYGGQRGDAHGKPGVLHGELEPHDHTSRLERHDLHSQLPTSVQVRHHWWEGALDLAKKRQQQTSINVFTTIKQGSRCDRWMVLGAISLLYNQEEAPDDRPLRARREVRSQHLSWAFPGTAGPGLVCAGDSQ
What are the official names of this protein?
Uncharacterized protein UMODL1-AS1, UMODL1 antisense RNA 1, UMODL1 antisense gene protein 1.
Protein: ACTD_STRPU
Sequence: MCDDDVAALVIDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVFDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMQTAASSSSLEKSYELPDGQVITIGNERFRAPEALFQPAFLGMESAGIHETCYNSIMKCDVDIRKDLYANTVLSGGSTMFPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, cytoskeletal 2B, Actin, cytoskeletal IIB.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: HASC1_STRPQ
Sequence: MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFDILERQVPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVPTHSK
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase 1, Alpha-D-glucosyl-1-phosphate uridylyltransferase 1, UDP-glucose pyrophosphorylase 1, UDPGP 1, Uridine diphosphoglucose pyrophosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.