PharMolix/UniProtQA huggingface dataset:
Protein: TRM44_ASPFU
Sequence: MPRNVKKNPRDVTKLSGKPLAETIEPSPVLKTLQEGWVTSPDLIEGDLSFTLEVIQNMTVFLLANPNLNSSHLFRADILYDSLGVLSAPHAMEQSRDQGSGGRDQDTQKEDYVEPLPARSVPGFELKRTFVRRLIPRNRNLDRPLEQTCHFYEADELPPTSNSTNIAQSEQCESKAESPRQRFLVIYLPHVSSKEEMPWYHPLLRSLAFLYDFTPNAFPHSSEENKGTGIMSVHFLPYEEEPIQNRLERTLLALLSTHIRLARQTRLDEKPEGGNYNPHKDNVIPKHLVQDTYARLKLKYAADLCQNWVEDTEPTKHVFEDLSITAFLIELWRSMYGVVPADERSPDQKEQGKYDLKFPGFVDVACGNGVLVYVLLSEGYHGWGFDARRRKTWSIFPSSIQERLKEEIYIPKPFADVCTDSEMDFGVKTHTGMFPEHTFIISNHADELTVWTPLMAALSNPASPLPFISIPCCSHSLSGARYRYPPPKPNQKGSVDRPEDQEVEQNPQPAAGDLKALRAAKQKERTDTGAANSMYGSLTAKTVATAEEIGYEVEKTLLRIPSTRNMGVIGGRRRTTQEWTSRVHSAQASQAVGCSAPEAVRAAAQVLEWVAAVVQRECAREGGVEVAAKVWIERAKGLHKGQGKGNQPAH
What is the function of this protein?
Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
What are the official names of this protein?
tRNA (uracil-O(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TRM44 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_WOLPM
Sequence: MIQKNTLLEVADNSGARAVLCIGLLGGRKSASIGDTVIVSTKSITPRGKVEKGKVYRAVVVRVKSPIRKSDGSVIRFSSNAVVLINDQGEPLGTRVFGPVKKLSSGSFMKIMSLAVEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SY63_DIPOM
Sequence: MSGDGEDELCRNALALVNELCFSVRGNHNNEKCIEFSYLLRDRDRTRHIETDISVSLLSVIVTFCGIVLLGVSLFVSWKLCWIPWRDKGLNPQRRDSQHHPHQHLHHHHSHFTDLTVERVDCGPEMPERSYLDLESYPESGIKLSQTSPDIPVDTSSGSKENNIPNAHSQQQVSAPPPATRFNSLPRPIPQQLSSPEFGTQADEKVEQVTSIGQIKPELYKQRSIDTEAKKHQKVNCGRINFMLRYTYTTEQLVVKILKALDLPAKDANGFSDPYVKIYLLPDRKKKFQTKVHRKTLNPIFNETFQFNVPFNELQNRKLHFSVYDFDRFSRHDLIGQVVLDNLLEFSDFSEDTTIWRDILEATSEKADLGEINFSLCYLPTAGRLTITIIKATNLKAMDLTGFSDPYVKASLICDERRLKKRKTSIKKNTLNPVYNEALVFDIPNENMEHVNVIIAVMDYDCIGHNEVIGMCRVGNATDGPGREHWNEMLANPRKPIEQWHQLIEEKVMNSYMTKSFAAGTGATKPVTIVVESPHSV
What is the function of this protein?
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse.  It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
What are the official names of this protein?
Synaptotagmin-C, Synaptic vesicle protein O-p65-C.
What is the protein family that this protein belongs to?
Belongs to the synaptotagmin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Synapse. Note=Synaptic vesicles in neurons.
Protein: TRPD_SYNPW
Sequence: MVSSPMSWSKRLDHLLNGGVFSHAEATELMEAWLAEALTPVQTGAFLAALRSRGVDGTELGAMAAVLRQASPLPCERPTLGLVDTCGTGGDGADTFNISTAVAFTAAACGATVAKHGNRSASGKVGSADVLEGLGLHLKAPAAQVVSALPATRVTFLFAPAWHPALVNLAPLRKSLGVRTVFNLLGPLVNPLRPDGQVLGVATDDLLDPMAEALRSLGQDRAVVVHGSGGLDEASLAGPNPVRILEKGQVRSEWIAPEDLGLQQAPLDALRGGDLVRNQTILEELLSGRGSQAQNEVVAFNTALVLWVAGVESDFKQGAQKALAALSQGSPWSRLEQLRAALSPAKEE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ACCD_EXIS2
Sequence: MQAFFRKPKKFVTLTSKEQRVDVPVGLMTKCPKCKLIQYTKQLEANLKVCVCGYHHPLTATERFEQLFDAGTITYFDLPAVKADPLDFQDYPEKLKGDQVRTGLEEAIVCGVGQVNGYPLVACVMDARFRMGSMGAAVGAAISEAIRYATKERLPVTIFSASGGARMQEGMVSLMQMAKSSLFLKQHSDAGLLYVSCMTHPTTGGVSASFAMLGDFNIAEPGALIGFAGRRIIEQTIREKLPEDFQTSEFLLQAGQLDDVVSRHDLKTYYTRILMMHSEETNHATI
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_STAAT
Sequence: MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYVVKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGCAIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQARRIAFNINIPKESVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINFDDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTINHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVEAVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: SH_RAT
Sequence: MAHAVRSKSNWCWQTYLLERINQVFSISLPPRAQPIGPVLAGAAFQTHSQQNNSGHQFGDRFHSKGHQDTEGRILWKEASTRTTDSTETADTQLVQRQGNGGICLS
What is the function of this protein?
May be involved with the regulation of GNRH gene expression.  It is not known if this protein is transcribed.
What are the official names of this protein?
Putative protein SH, SH-4.
Protein: SYH_STAA2
Sequence: MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIKTAPRITDFLNEESKAYYEQVKAYLDDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_METKA
Sequence: MRDALGREVRSVRISVTMRCNMACVYCHREGERPGRSELSAAEWGRLLRACAEIGVRKVKITGGEPLLRRDLIEIIENAEGFEEVSLVTNGVLLADYAGDLAEAGLDRVNVSLDTVDRKLYRKLTRSRFSPDDVIRGIEAAVSEGLTPVKVNVVLTSETVKTLPTLVEELADLEGLKLQLIEPMGSIPGFRPAHAEDGLRALGEYEPELERVRTFHSREVYRLNNGMAVEVVKPMDGVMCEACTRIRLTHDGKYKGCLMAPPKPLPRDDFGELVRTLKEYVRTRDDTFEVHQGTSVMGRMRGDVSGR
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
Probable GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: RL331_SYNSC
Sequence: MAKNKGVRIVITLECTECRSNPAKRSPGVSRYTTEKNRRNTTERLEIKKFCPHCNKSTIHKEIK
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ACPS_AZOSB
Sequence: MIHGIGTDIVHIARIRTSLERHGERFAERILAESEREAWRASRDPARFLAKRFAAKEAFGKALGTGVAVPATLHAVAVDHDALGKPLYRYGDGLQTYLDDRRLNAHLSLTDENDYVVAFAVIETR
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLUD_NEIMA
Sequence: MQNTSFDNESDYSDDSDFASASETENRIGLTVPLELAGGRLDAVLAKLLPDYSRSRLTLWIKEGAVIVNDKPSQPKDKMIGGEQIRVTVRPSEENLAFVPEPMALDIVYEDDTVIVVNKPAGLVVHPAAGNWTGTLLNGLLAHCPELSQIPRAGIVHRLDKETSGLMVVAKTLPAQNSLVWQLQERTVKRIYRAVANGIVPFDGKIETQIGRDPHNRLKMAVVKFGGKPAVTHVKVLERYLAHSYIECSLETGRTHQIRVHMREANHPLAGDPVYGNPRHPCGDTVKEAVKSLGARQALHAYRLSFTHPESGETVSFEAPIPDDIYHLLSVLRLEAGLDSSLSNEEEWQDKFGADDDDDWNEDDYDVEVVYVRE
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: PTH_STACT
Sequence: MKCIVGLGNIGKRFEQTKHNIGFEVIDYLLESNQFKLDKQKFRGAYTIERLGGEKVLLIEPMTMMNLSGEAVGPLMDYYNVDPEDLLVLYDDLDLPQGQVRLRQKGSAGGHNGMKSIIQHLGTDNFKRIRIGIGRPTNGMSVPDYVLQKFSKQEMETMNKVIEHSAHAVEDYVSNSRFDHVMNEYNGEVS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOP2_MOUSE
Sequence: MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYERTDALLLRLSVVVGREVFYAALWGSVLTSPSIRLPASLFVVNHISRDSPGKEQKCMLGTDYQLTVRSLCASLLDANVLVQRNNLEIILFFFPFYTCLDPEERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPKSEISNSYEDQCSYFFDKYSKDLLVEALAEILHQKFLDADLEERHHAYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNPLISTIKENRHASEIVKTVNLLVSSLSSDFLWDYMARRFEACFRPVTQTTAIGEAISPPPTVSELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQMPPSYLDLEPSSGNSSPVKGRNSGIAMETEAVVAGDEEPSFPPLKSEDSGIGLSASSPELSEHLRVPRVSAERDDIWKKDGTMQATFLCIQELIANFASKNIFAASLTVSGEENKPEEPPGKGNKGQTQSTEHPGRKSSWDPKPITVPQFKQMLSDLFTVRGSPFKTRSSESLSSVPSSPHRKAATEWGVDQVVVELVGSKEDCREALAAACHLLLDCATFPVYLSEEETEQLCETLFQTPGASDCSFPPWLKSLMTICCCVSDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQENSAEDLHRWFNRKKPTCKEACGESEPQEGAPEERLPRGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDLPYYVDLPDRMTSGGGDSSEHTESADTSSGHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEADVELQAITTSRLLKQQREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDILGNRDVQVKSVEVLIRITAQLVSMAKSAEGKNTEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATADRGGRLLAEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEEAETQPALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDDLVKQYESESVKFTISTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLRKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWNRKQARRHSKTKMVPVANTSQHTLVDLVCALSTLQTDSVLQLVKEVVKRPAQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQEAFPSLLGVLKEAAQLNLAPPGYFLLLSMLNDFVTRTPNLESKKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLEESDAEDDVHSAAEASTMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCVHWKSVIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEDESRNSHKSNRIKAPVADGNGSAGRVLSPSDLTMYLSACKFLDTALAFPPDKMPLFQIYRWAFVPEVDTEHPAFLSELEENHQECRPHTVRILELLRSRYGEIGSSDEITRKKEFPLLRQHSVSCIRQLIPFFTTLNCAFKTQSQLPADVPGTAAPECPVTENPRVLRQLEECVEQDFLEHPEC
What is the function of this protein?
May play a role in regulating membrane trafficking of cargo proteins.  Together with ATP9A and MON2, regulates SNX3 retromer-mediated endosomal sorting of WLS away from lysosomal degradation.
What are the official names of this protein?
Protein dopey-2.
What is the protein family that this protein belongs to?
Belongs to the dopey family.
What are the subcellular locations of this protein?
Early endosome membrane. Golgi apparatus membrane; Peripheral membrane protein.
Protein: PROA_NEIM0
Sequence: MSNTQKQLALAKAAKKSVNTADTEEKNRALLAMADSLEAAAADILAANRQDLEAAAGNIPESMTDRLLLDGKRICAMADGIRAVAALPDPVGEILETSTLPNGLEIVKKRVAMGVIGIIYESRPNVTSDAAALALKSGSAVVLRSGKDAFQSARAIVAALKAGLAQTRIDPDALQLIEDTGREGSYEMMRAKDYLDLLIPRGGAGLIRAVVENAVVPVIETGTGIVHIYIDKDADWDKALRIVYNAKTSRPSVCNSMEVLLVHEDIAADFLPKLERLLVRDRIEAGLPPVRFRLDPQAARHIGGEAAGADDFDTEFLDYILAVKTVASVEEAVWHIETHSTHHSDGIVTENRHAADYFTTHIDSAAVYVNASTRFTDGGEFGLGCEMGISTQKLHARGPMGLKELTSYKYIVQGTGQVRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UGA3_YEAST
Sequence: MNYGVEKLKLKYSKHGCITCKIRKKRCSEDKPVCRDCRRLSFPCIYISESVDKQSLKKIKADIQHQLISKKRKHAPDSAQKAAVATRTRRVGSDEQDNQVYLSKPLEDCISQKLDSMGLQLYNYYRSHLANIISIAPMNQNYYLNIFLPMAHENDGILFAILAWSANHLSISSSNELRKDEIFVNLANKYTYMSLSHLKTNEGSSACAKLGFLYSLAQILILCGSEICQGDVKFWKILLNIGKNLIENHVGKDVSRILTTTTEEPSLEERIIFPNFNSVVKYWLIVNFIYHDILNFNTTSFPIEQYEKFFQRDQNSLPSSANFIESIDSPIEEIDPLIGINKPILLLLGQVTNLTRFLQTMEQEEMLEHGDKILSLQVEIYKLQPSLMALEHLDDEKKFYYLELFEIMKISTLMFFQLTLLKIDKDSLELQILRNKLDSKLDKVIGTFLEGSLCFPLFIYGVCIQVEDMEKKIDLEAKFDDILKRYKCYNFQNARLLIRKIWQNEADGISEHDLVHMIDELDYNINFA
What is the function of this protein?
GABA-dependent positive regulation of genes required for catabolism of GABA (UGA4, UGA1, and UGA2).
What are the official names of this protein?
Transcriptional activator protein UGA3.
What are the subcellular locations of this protein?
Nucleus.
Protein: PARP3_MEDTR
Sequence: MKVESRSHNVHHAHGEEEKVMTRKQKAESKAHEVEHSPKKAKVEDEKNGHTNGKSASDVVQEYDEFCKATNEQLSLEQMKEILEANDLDSSGSDLEITRRCQDLLFFGALEKCMVCNGNMEFDGRRYGCRGFYSEWSSCTFSTREPPRKDEPIKLPDSVQNSPVSDLLKKYQDPSKRPQRDLGLAIKPFTGMMISLMGRLNRTHLNFSGASCLVASPAERDRGGTSKLADAMERGIPVVREAWLTDSIEKQEPQPLESYDLVSDLSVDGKGIPWDKQDPGEEAIESLSAELKLYGKRGVYKDTKLHEQDGKIFEKDGILYNCAFSLCDQGRKLNDYCVMQLIVVPENSLHLYFKKGRVGDDPSAEERLEECENVDNAIKEFVRLFEEITGNEFESWEREKKFQKKPLKFYPIDMDDGVEVRHGALGLRQLGIAATHCKLEPMVANFMKVLCSQEIYKYALMEMGYDSPDLPIGMVTNLHLKRCEEILLEFIEKVKTLKETGPKADAIWSDFSQKWFTLMHSTRPFIFRDYQEIADHAAAALEGVRDITLASHLIGDMSGSTIDDPLSDTYKKLGCSITPLEKNSNDYEMIVKYLEKTYEPVKVGDIEYGVSVENIFTVESSACPSYADIVKMPNKVLLWCGSRSSNLLRHLHKGFLPAICSLPVPGYMFGKAIVCSDAAAEAARYGFTAVDRPEGFLVLAIASLGNEITELKSPPEDTTSLEEKKVGVKGLGKKKTDESEHFVWKDDIKVPCGSIIASEHEDSPLEYNEYAVYDPKQVRISYLVGVKYEEKDAVIDTAE
What is the function of this protein?
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism.  This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks (By similarity).
What are the official names of this protein?
Protein ADP-ribosyltransferase PARP3, NAD(+) ADP-ribosyltransferase 3, ADPRT-3, Poly[ADP-ribose] synthase 3, Putative poly [ADP-ribose] polymerase 3, PARP-3.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL5_ECO7I
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL30_STRPI
Sequence: MAQIKITLTKSPIGRIPSQRKTVVALGLGKLNSFVIKEDNAAIRGMITAVSHLVTVEEVN
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ASNA_BABBO
Sequence: MVEITEVIEPEWQTRNDIQNLVNQKTLQWVFVGGKGGVGKTTISSSIATALAETRESVLLLSTDPAHSLSDAFGQKFTHEPRLVNGFTNLYAMELNTSQIIDGLDGLRETHSFLKNVPDILMMLPGIDEALSFVELMQSVQSRRFSVTIFDTAPTGHTLKFLKLPDVLEKILDSLLKLENTMGGLLQLFSSMTKAQMSQNELFDKIKLLGDMINTTHEQMKNPDLTTFICVCIPEFLSVYETERLIQDLAKSEIDCSYIIVNQVLKHIQLGGLIEDAWDGLTEEQQRIMTPFFEKVREHHSTHNSRVDVQRKYLSDIKDLYQEDFNIVAVHQNKQEVRGKDALVAFAKKLMQHSPLPI
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: RS4_AERPE
Sequence: MGDPRKPRKKWEGPKHPWIKERLERERELMGRYGLRNKKELWKAETLARRFRHRARSLLGLPPEVRREASRVLVESLYRMGLIDNPNVDIDEVLGINAEKVLERRLQTIVYKKGLAKTIYQARQLVVHGHIAIAGRRVTSPGYLVSREEEKLIDYAPGSPFKERAEEAAQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: OPAJ_NEIGO
Sequence: MNPAPKKPSLLFSSLLFSSAAQAAGEDHGRGPYVQADLAYAYEHITHDYPEQTDPSKGKISTVSDYFRNIRTHSIHPRVSVGYDFGGWRIAADYARYRKWNNNKYSVSIKELLRNKVNGNRTDRKTENQENGTFHAVSSLGLSAVYDFKLNDKFKPYIGARVAYGHVRHSIDSTKKTTEVTTILHGPGTTPTVYPGKNTQDAHRESDSIRRVGLGAVAGVGIDITPNLTLDAGYRYHYWGRLENTRFKTHEASLGVRYRF
What is the function of this protein?
Implicated in a number of adherence functions.  OPA proteins are implicated in pathogenesis and are subject to phase variation.
What are the official names of this protein?
Opacity protein opA58.
What is the protein family that this protein belongs to?
Belongs to the opacity porin family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RRF_CLOBB
Sequence: MIKDIIKNAEEKMQKTVTVLKSELGTMKAGRANPSMLDKIQIDYYGSMCPLSQAANISSPEPRVLMITPWEKQLLKEIEKAILKSDLGLNPSNDGSIIRLVIPELTEETRKDLVKKVKKTGEESKVAIRSIRRDANDKIKALKKDGDLSEDQVKKGEDDVQKKTDAIIKDIDKIIVDKEKEILAI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_CLOBA
Sequence: MEFYPVAIEKLIEEFAKLPSIGKKTAQRLTLHILNLPDDEVREFAKALVKAKGTIKYCSTCGNFTDTDPCALCSNPNRDKSTICVVEQPKDIMTMEKVKEFNGLYHVLHGNISPMQGRGPQDIKIRELVARMNEEVKEVILATNPNIEGEATAMYIAKVLKPLDVKVTRIAAGIPVGGDLEYADEVTLSKALEGRKEI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HSP6C_DROME
Sequence: MPDIPFVLNLDSPDSMYYGHDMFPNRMYRRLHSRQHHDLDLHTLGLIARMGAHAHHLVANKRNGELAALSRGGASNKQGNFEVHLDVGLFQPGELTVKLVNECIVVEGKHEEREDDHGHVSRHFVRRYPLPKEFDSDAIVSTLSEDGVLNITVPPLVSKEELKERIIPIKHVGPSDLFQNGNGHKEAGPAASASEPEAK
What are the official names of this protein?
Heat shock protein 67B3, Heat shock 18 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: ITPA_YARLI
Sequence: MSVVFVTGNAGKLRETNHILAPTGIELTSHKLDLEETQGTIEEVSIAKAKAAAKILNKPVLVEDTALGFAALKGLPGVYIKWFLDSLGHEGLNKMLAGFEDKSATAWCTFAYCGGPDEDVLLFQGTCEGTIVPPRGENNFGWNAVFEPKGYTETFAEMSEETKNAISHRFKALEKLKVFLAEKAEQSK
What is the function of this protein?
Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FMT_BURPS
Sequence: MTHSLRVIFAGTPEFAAAALAAIHEAGFPVPLVLTQPDRPAGRGMKLQASAVKRYALERGMAVAQPPSLRRAGKYPAEAVAALDLLHATPHDVMVVAAYGLLLPQEVLELPRHGCINIHASLLPRWRGAAPIHRAIEAGDAETGVTLMQMDAGLDTGAMLHEARVAIAPDDTTATLHDKLAAAGARLIVDALVELERTGALAATPQPADGVTYAEKIGKHEAALDWRKPAAALARQVRAFDPFPGGAGTLDGATLKLWAADAVPGRDDAAPGTIVDIGPDGVVIACGEGALRVTQLQKPGGKRLPAREFLAGAPLAVGQRFAPADAA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: NUSB_STRP6
Sequence: MTNSFQNSRRDLRERAFQALFNIETGAELLAASQFAYGYDKVTGEDAQVLELPIFLLSLVTGVNNHKEELDNLISTHLKKGWSLERLTLTDKTLLRLGLFEIKYFDETPDRVALNEIIEVAKKYSDETSAKFINGLLSQYVSEAPSANKS
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.