PharMolix/UniProtQA huggingface dataset:
Protein: RL5_BREBN
Sequence: MATRLKEKYTSEIVPSLMSKFNYTSIMQVPKVEKIIINMGVGEAVANAKSLDTAIEDLQIIAGQKPVVTKAKKSIAGFKLREGMPIGAKVTLRGERMYHFLDKLMNVSLPRVRDFRGISSKAFDGRGNYTLGLKEQLIFPEIEYDKIDKVRGMDIVVVTSAKTDEEARELLTQMGMPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: GPPS_MYCTU
Sequence: MIPAVSLGDPQFTANVHDGIARITELINSELSQADEVMRDTVAHLVDAGGTPFRPLFTVLAAQLGSDPDGWEVTVAGAAIELMHLGTLCHDRVVDESDMSRKTPSDNTRWTNNFAILAGDYRFATASQLASRLDPEAFAVVAEAFAELITGQMRATRGPASHIDTIEHYLRVVHEKTGSLIAASGQLGAALSGAAEEQIRRVARLGRMIGAAFEISRDIIAISGDSATLSGADLGQAVHTLPMLYALREQTPDTSRLRELLAGPIHDDHVAEALTLLRCSPGIGKAKNVVAAYAAQAREELPYLPDRQPRRALATLIDHAISACD
What is the function of this protein?
Catalyzes the addition of isopentenyl diphosphate (IPP) onto dimethylallyl diphosphate (DMAPP) to form geranyl pyrophosphate (GPP) (PubMed:21237161, PubMed:30301210).  Is probably involved in the biosynthesis of decaprenyl diphosphate, which is required for mycobacterial cell wall synthesis (PubMed:21237161).  Could be required for host endothelial-cell invasion and/or intracellular survival (PubMed:16586367).
What are the official names of this protein?
Dimethylallyltranstransferase, Geranyl diphosphate synthase, GPP synthase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: YN075_YEAST
Sequence: MPIIGVPRCLENPFCAPAKFPLSVKKKIRI
What are the official names of this protein?
Putative UPF0377 protein YNR075C-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
Protein: MAP2_COCP7
Sequence: MAVQALPEINKLSVSEEGAANAAAKGQAAQGTAGNDDAENDESDEDKEDEQEVADGAAAAGGKKKKKKTKKKKKKGTAKVQSDPPRVPLSTLFPNNNYPEGEIVEYKDDNAYRTTNEEKRYLDRMNNDFLTDYRKSAEIHRQVRQYAQKELLKPGRSLTEIAEGIEDSVRALTGHMGLEEGDSLVAGMGFPTGLNINHCAAHYSPNAGNKMVLQYGDVMKVDFGVHVNGRIVDSAFTVAFDPVYDNLLNAVKDATNTGIREAGIDVRMSDIGAAIQETMESYEVEINGTIYPVKAIRNLNGHTIGHYLIHGGSTGKSVPIVKGGDQTKMEEGETYAIETFGSTGKGFVRDDMEVSHYAKVPDAPNVPLRLSSAKNLLNVITKNFGTLPFCRRYLDRLGQEKYLLGLNNLVSSGLVDAYPPLVDVKGSYTAQFEHTILLRPNVKEVITRGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5M_WHEAT
Sequence: MYLLIVFLPLLGSSVAGFFGRFLGSEGTAIMTTTCVSFSSILSLIAFYEVALGASACYLRIAPWISSEMFDASWGFLFDSLTVVMLIVVTFISSLVHLYSISYMSEDPHSPRFMCYLSIFTFFMLMLVTGDNFLQLFLGWEGVGLASYLLIHFWFTRLQADKAAIKAMLVNRVGDFGLALGIFGCFTLFQTVDFSTIFACASAPRNEWIFCNMRLNAITLICILLFIGAVGKSAQIGLHTWLPDAMEGPTPVSALIHAATMVTAGVFMIARCSPLFEYSPTALIVITFAGAMTSFLAATTGILQNDLKRVIAYSTCSQLGYMIFACGISNYSVSVFHLMNHAFFKALLFLSAGSVIHAMSDEQDMRKMGGLASSFPLTYAMMLMGSLSLIGFPFLTGFYSKDVILELAYTKYTISGNFAFWLGSVSVLFTSYYSFRLLFLTFLVPTNSFGRDRLRCHDAPIPMAIPLILLALGSLFVGYLAKDMMIGLGTNFWANSPFVLPKNEILAESEFAAPTITKLIPILFSTSGASLAYNVNLVADQFQRAFQTSTFCNRLYSFFNKRWFFDQVLNDFLVRSFLRFGYSVSFEALDKGAIEILGPYGISYTFRRLAERISQLQSGSVYHYAFAMLLGSTPFVTFSRMWDSLSSWVDSRSSFILLVSSFLINKSSQE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CO1A1_HUMAN
Sequence: MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCDNGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-1(I) chain, Alpha-1 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RS16_ESCF3
Sequence: MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DDL_HAEIN
Sequence: MNLKQEKIAVLLGGTSAEREVSLNSGKAVLEALLKQGYNAHPIDPKEYNVANLKKDGFNRAFNILHGRGGEDGTMQGLLEQIGLPYTGCGVMASALTMDKMRTKMLWKAFGLPVADMKVVTRETFSELDPQAVVAKLGLPLMVKPSLEGSSVGLTKVKAVEELKSAVEYALKFDNTILIEEWLAGDELTVPVLDNQVLPAIRIVPEGEFYDYEAKYISDNTQYFCPAGLTPEREQALSTLVKRAYDAVGCRGWSRIDVMCDAKGNFRLVEVNTNPGMTSHSLFPKSAATVGISFEQLVVKILELSL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRIB_ECOBW
Sequence: MTNRLVLSGTVCRAPLRKVSPSGIPHCQFVLEHRSVQEEAGFHRQAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDSGD
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).  During primosome assembly it facilitates the complex formation between PriA and DnaT.
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: RIMO_CHLAB
Sequence: MTTKEQFFFKGATSKNKIHFISLGCSRNLVDSEVMLGILLKAGYEATELLREADYLILNTCGFLKAARDESTDYLQRIINEKKETAKIILTGCMVSKHKEELKPWLPYVHYVLGSGDVEHILSAIESKESGEKLSSKSYLEMGEVPRKLSTPKHYAYLKIAEGCRKRCAFCIIPTIKGGLRSKPLEQVMKEFRLLLKMGVKEIILIAQDLGDYGKDLSKDRKSCLYSVLREMLKEPGNYWIRMLYLYPDEVDDTLIDLMEKDQRLLPYVDIPLQHINNRVLKKMLRTTSREQILDLLTKLRTRIPHIYIRSSLIVGFPGETEEEFQELVNFVGEGWIDNLGIFSYSQEKGSLAAEMPDQIPQSVKSKRLKILSQTQKKNVEKHNKQFVGKIVEAVIDGYHPDSEFLLTARFYGQAPEVDPCIIVNEARLVSGFGERYLIEITGYVGYDLVGRVVNKVPGE
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASSY_PAEAT
Sequence: MTERIVLAYSGGLDTSVAIGWIGEATGAEVIAVAVDVGQGGESLETIRQRALGCGAVEAYVADARDEFANEYAMPTLKANALYQGHYPLVSAISRPVIVKHLVKAAREFGATTVAHGCTGKGNDQVRFEVGIQTLGPDLKCIAPVRDLALTRDKAIAFAEEKGLPIETTKKNPYSIDQNVWGRAVETGYLEDIWNAPTKDIYDYTATPEFPPAPDEVIISFQAGVPVAIDGVKVTPLQAIQELNRRAGAQGVGRIDVVEDRLVGIKSREIYEAPGAMALITAHKHLEDITIEREQARFKATVGQRWAELVYDGQWFSPLKRSLDAFIEDTQQYVSGDIRMVLHGGQAVVNGRRSETSLYDFDLATYDTGDTFDQSMARGFIELWGMSSKVASGRDLRVAGQ
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS3X_CVCAI
Sequence: MLNLVSLLLKKSIVIQLFDITVYKFKAKFWYKLPFETRLRIIKHTKPKALSATKQVKRDYRKTAILNSMRK
What are the official names of this protein?
Non-structural protein 3x, ns3x, Accessory protein 3x, ns3b.
Protein: MUG_SALTI
Sequence: MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLAGFTDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIEKIEDYQPAALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELDQALIMRGL
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COXX_CORDI
Sequence: MNMLEETLETIKAYVALTKPRVIELLLVATIPAMLQAERGENNIGLILLTLLGGWMGAAAANTFNMVADSDIDQKMGRTRARPLVRNKVSNRHASVFAWTLTVVSFLWLWVLCRSVLAGLFILLTIFFYIFVYTKYLKRKTHLNIVWGGAAGCMPVVVGWAVITDNLPAGTPAQWWQAIVLFMVIFFWTPPHTWALAMKYKDDYARAGVPMLPVVRTPVEVTRQIVWYTVATVLTTFLLIPAASWIHAIIAVVSGVWFLVMAVRLHNGIKNGGEVKPLKLFILSNNYLAVYFVGLSIDAVLGWETIGGHLGWTTTFF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNME_PROMP
Sequence: MESIIDTEDTIAAIASAVSLGKGGIAVIRVSGEEAINSCKNIVETKSKYAWESHRVFHGFIKDNLENKFIDEILITVMHSPNSFTGEDIVELHCHGGVIVVNKVIETLLSNNTGVRIANPGEFSQRAFLNGKIDLTQAESINQLINAKNLKSAEIAFNGVKGEIKKKIDIIKNDLIEQLSEIEARVDFEEDFSEFNYNDFSRNIKIIKEKIKILIENSKRGAHIHNGISIALIGKTNVGKSSLLNLLSKKEKAIVTSIPGTTRDIIEVNLTIKDIPIKIIDTAGIRETDEYIENIGIDKSFEMIQNSDYIIYLYSLEEGLNKDDEKIISKIPQEKLITILGNKKDLIDSKKVNKKNLSNSVLMSIKNDEGEKELVEKIVKKCGSKEFENIDIFLNERQISNLTDCLKNLNDTDPIIANKLPFDLLSIEVRDGIKNLSRITGQELTEDLLNNIFSKFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTSA_ENT38
Sequence: MGRLVVVSNRIAPPDDKKSSAGGLAVGILGALKTAGGLWFGWSGEVGNEDKPLQKVTRGNITWASFNLSEQDHEEYYSQFSNAVLWPAFHYRLDLVKFQRDSWEGYTRVNALLADKLLPLIEEDDILWIHDYHLLPFASELRKRGVNNRIGFFLHIPFPTPEIFTAIPPHEELLEGLCDYDLLGFQTENDRQAFLESVAGKTRLTTHNGKSHQAWGKTFDTEVYPIGIEPDEIAADASGPLPPKLAQLKNELKNVKNIFSVERLDYSKGLPERFQAYERLLEKYPQHHGKIRYTQIAPTSRGEVQAYQDIRHQLETEAGRINGRYGQLGWTPLYYLNQHFERKVLMKVFRYAEVGLVTPLRDGMNLVAKEYVAAQDPKDPGVLVLSQFAGAANELTSALLVNPYDSDDVANALDRALKMPLTERISRHAEMMKVIRENDINHWQETFIRDLKRTTPRSVESNLQKKIATFPKLA
What is the function of this protein?
Probably involved in the osmoprotection via the biosynthesis of trehalose.  Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate.  Acts with retention of the anomeric configuration of the UDP-sugar donor.
What are the official names of this protein?
Trehalose-6-phosphate synthase, TPS, Alpha,alpha-trehalose-phosphate synthase [UDP-forming], Osmoregulatory trehalose synthesis protein A, OtsA, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: PYF3_PENMO
Sequence: YAIAGRPRF
What is the function of this protein?
May act as a neurotransmitter, neuromodulator or neurohormone.
What are the official names of this protein?
Peptide tyrosine phenylalanine 3, Pem-PYF3.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: EFG1_PSEAE
Sequence: MARTTPINRYRNIGICAHVDAGKTTTTERVLFYTGVNHKLGEVHDGAATTDWMVQEQERGITITSAAVTTFWKGSRGQYDNYRVNVIDTPGHVDFTIEVERSLRVLDGAVVVFCGTSGVEPQSETVWRQANKYGVPRIVYVNKMDRQGANFLRVVEQIKKRLGHTPVPVQLAIGAEENFVGQVDLIKMKAIYWNDDDKGMTYREEEIPAELKDLAEEWRSSMVEAAAEANEELMNKYLEEGELSEAEIKEGLRLRTLACEIVPAVCGSSFKNKGVPLVLDAVIDYLPAPTEIPAIKGVSPDDETVEDERHADDNEPFSSLAFKIATDPFVGTLTFARVYSGVLSSGDSVLNSVKGKKERVGRMVQMHANQREEIKEVRAGDIAALIGMKDVTTGDTLCSIEKPIILERMDFPEPVISVAVEPKTKADQEKMGIALGKLAQEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMKREFGVEANIGKPQVAYRETITKDNVEIEGKFVRQSGGRGQFGHCWIRFSAADVDEKGNITEGLVFENEVVGGVVPKEYIPAIQKGIEEQMKNGVVAGYPLIGLKATVFDGSYHDVDSNEMAFKIAASMATKQLAQKGGGKVLEPIMKVEVVTPEDYMGDVMGDLNRRRGLIQGMEDTVSGKVIRAEVPLGEMFGYATDVRSMSQGRASYSMEFSKYAEAPSNIVEALVKKQG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 1, EF-G 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REV_EIAV9
Sequence: MAESKEARDQEMNLKEESKEEKRRNDWWKIDPQGPLESDQWCRVLRQSLPEEKIPSQTCIARRHLGPGPTQHTPSRRDRWIRGQILQAEVLQERLEWRIRGVQQAAKELGEVNRGIWRELYFREDQRGDFSAWGGYQRAQERLWGEQSSPRVLRPGDSKRRRKHL
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry two recognition sequences that function as Rev responsive element (RRE), that are not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity).
What are the official names of this protein?
Protein Rev, 3'-ORF protein.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: DAPD_BRASO
Sequence: MSLSALESTINSAFDARDGVSTSTKGEVRDAVESALELLDKGEARVAERAADGKWSVNQWLKKAVLLSFRLNDMSVIPGGPGQASWWDKVPSKFEGWGENRFREAGFRAVPGAIVRRSAFIARNVVLMPSFVNLGAYVDESTMVDTWSTVGSCAQIGKRVHISGGVGIGGVLEPLQAGPVIIEDDCFIGARSEVAEGVIVRKGAVLAMGVFLGASTKIVDRETGETFVGEVPEYAVVVPGALPGKPMKNGQIGPSTACAVIVKRVDERTRSKTSINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_ACIF2
Sequence: MHSSTHDDLVILGGTFDPIHYGHLRAVEEVRQALAIAQAMLIPAGHPPHRKSPWADARHRLAMTRIAVAHHPQFTVSSWEVEREGPSYTVDTLTALRQQRPDAVLAMVIGMDAFLRFDTWHHWQHILDLTHLVVTGRPGWPAAELPEALRQALYQRRCEDVDALRQTPAGCILFHTVTALEISASNIRSLLAGHQSPRFLLPDEVLDYIDAEGLYQSP
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: DPCKG_PYRAB
Sequence: MKVLFKLPPSLRSELKKPVGELIEGDIPTPYLKVKDILTNEDPLVTVGDVVTENIMKVGLNPNLAIYDHKTERREYKPNIRSVEGVLITVKNPPGTITLPLLKAIKKAYSLLSHGKRVHIVVDGEEDLATIPAVLYAPIGTTVIYGQPKKGIVLIKVTNECKRRCAKIMRRMEVVRNGD
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: CH10_THET2
Sequence: MAAEVKTVIKPLGDRVVVKRIEEEPKTKGGIVLPDTAKEKPQKGKVIAVGTGRVLENGQRVPLEVKEGDIVVFAKYGGTEIEIDGEEYVILSERDLLAVLQ
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB2_PSEUR
Sequence: VEWTDFERATIKDIFSKIEYEVVGPAALARCLVVYPWTQRYFGKFGNLYNAEAITGNPMISKHGTTILHGLDRAVKNMDDIKNTYAELSVLHSETLHVDPDNFKLLSDCLTIVVAGQLGKDFTGEVQAAFQKFLAVVVSSLGRQYH
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-2, Beta-2-globin, Hemoglobin beta-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DAPH_CLOB1
Sequence: MSYNLTDPYEIARYIKEAKKSTPIKAYIEGDLSNCDFTNIEKFNSGDLYILFGESEEILVIIEKNKDKIKNCRIEQDRRKSAIPLLDMLKINARIEPGATIRDKVIIGENAVIMMGAVVNIGAEIGEGTMVDMNAVVGARGKLGKNVHLGAGAVVAGVLEPPSSDPCTIEDNVLIGANAVILEGVKIGKGSVVAAGSIVTTDVPENVVVAGAPAKIIKEVDVKTKDKTKLLDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: YMFS_ECOLI
Sequence: MKIYCCLNTVGFFMDGCGVIPPDSKEITAEHWQSLLKSQAEGGVIDFSVFPPSIKEVIRTHDDEVADANFQKQMLISDATDFINSRQWQGKAALGRLKEDELKQYNLWLDYLEALELVDTSSAPDIEWPTPPAVQAR
What are the official names of this protein?
Uncharacterized protein YmfS.
What is the protein family that this protein belongs to?
To E.coli YfdK.
Protein: KATG_MYCBO
Sequence: MPEQHPPITETTTGAASNGCPVVGHMKYPVEGGGNQDWWPNRLNLKVLHQNPAVADPMGAAFDYAAEVATIDVDALTRDIEEVMTTSQPWWPADYGHYGPLFIRMAWHAAGTYRIHDGRGGAGGGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKKLSWADLIVFAGNCALESMGFKTFGFGFGRVDQWEPDEVYWGKEATWLGDERYSGKRDLENPLAAVQMGLIYVNPEGPNGNPDPMAAAVDIRETFRRMAMNDVETAALIVGGHTFGKTHGAGPADLVGPEPEAAPLEQMGLGWKSSYGTGTGKDAITSGIEVVWTNTPTKWDNSFLEILYGYEWELTKSPAGAWQYTAKDGAGAGTIPDPFGGPGRSPTMLATDLSLRVDPIYERITRRWLEHPEELADEFAKAWYKLIHRDMGPVARYLGPLVPKQTLLWQDPVPAVSHDLVGEAEIASLKSQILASGLTVSQLVSTAWAAASSFRGSDKRGGANGGRIRLQPQVGWEVNDPDGDLRKVIRTLEEIQESFNSAAPGNIKVSFADLVVLGGCAAIEKAAKAAGHNITVPFTPGRTDASQEQTDVESFAVLEPKADGFRNYLGKGNPLPAEYMLLDKANLLTLSAPEMTVLVGGLRVLGANYKRLPLGVFTEASESLTNDFFVNLLDMGITWEPSPADDGTYQGKDGSGKVKWTGSRVDLVFGSNSELRALVEVYGADDAQPKFVQDFVAAWDKVMNLDRFDVR
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.  May play a role in the intracellular survival of mycobacteria.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: MUP2_RAT
Sequence: NNVDKLNGDW
What is the function of this protein?
Binds pheromones that are released from drying urine of males.  These pheromones affect the sexual behavior of females.
What are the official names of this protein?
Major urinary protein 2, MUP 2.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMA_STRPF
Sequence: MIIKRREYMRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEIDQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDILKADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRISAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVEDEDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKAKLEKGLALADIKPSIRGEALSIQDFGKLADALKEVGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.