PharMolix/UniProtQA huggingface dataset:
Protein: IL1B_HUMAN
Sequence: MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQLRISDHHYSKGFRQAASVVVAMDKLRKMLVPCPQTFQENDLSTFFPFIFEEEPIFFDTWDNEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEESNDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVDPKNYPKKKMEKRFVFNKIEINNKLEFESAQFPNWYISTSQAENMPVFLGGTKGGQDITDFTMQFVSS
What is the function of this protein?
Potent pro-inflammatory cytokine (PubMed:3920526, PubMed:10653850, PubMed:12794819, PubMed:28331908).  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production (PubMed:3920526).  Promotes Th17 differentiation of T-cells.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells (PubMed:10653850).  Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6 (PubMed:12794819).  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore (PubMed:33377178, PubMed:33883744).  Acts as a sensor of S. pyogenes infection in skin: cleaved and activated by pyogenes SpeB protease, leading to an inflammatory response that prevents bacterial growth during invasive skin infection (PubMed:28331908).
What are the official names of this protein?
Interleukin-1 beta, IL-1 beta, Catabolin.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Lysosome. Secreted, extracellular exosome. Note=The precursor is cytosolic (PubMed:15192144). In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted (PubMed:24201029, PubMed:33377178, PubMed:33883744). Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore (PubMed:33883744). In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation (PubMed:33883744). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10 (PubMed:32272059).
Protein: PUR5_STAAW
Sequence: MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGATFDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYFLDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGAVEKDDYVDSSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVFLEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIFDWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIMKNESTAIELLGV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_CHLPM
Sequence: MRIGIGIDVHSFKEGRKLIVGGVDIPSPKGLDGHSDADVLLHAVSDALLGAAALGDIGLHFPDTSPEFKDIDSMILLKHVGKLLEKNGWRTVNVDAMLLLEAPKIAPFVVDMRKNIARCLQIETDLVSVKATTNEKLGYIGREEGAAAHAVCIIEKA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ZN704_DANRE
Sequence: MHTRRLVKRSVIGSRVYAPGLTGDAAPLTGVIQAVKQDNRDASTGHRRNVYTVLMQDGSVKEYSEEEIAQMTAKAPLKSSLKSTCNGGQRDGLTQGQNGGVQRGEALSLSPESTEEPRVLEHKRTGRALETEKDHTRSVSLLEQKRKVVSSSIDVPQARKSEEEVDMDKVTAAMVLTSLSTSPLVRSPPVKVSEGLNGSWKDGGFTPSSYSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRMPSLSGPPDDNIDEHDGNSLLFDEPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQRHIRTVHLGRNCDSECSDGEEDFYYTEIKLNTDSVADGLSSLSPVSPSVLSPPPALDQRQPDGTNGTKSESSSSTPLSRSAPSALYLVHTDHAYQATTPVTIPSTSSTGFTPSSSSFSISWQSPPVTFTGTSASPTHSRTQGFGEQHSQTIAVLSSPPRAAGSLSRKSRGEGKKCRKVYGMENRDMWCTACRWKKACQRFVD
What is the function of this protein?
Transcription factor.
What are the official names of this protein?
Zinc finger protein 704.
What are the subcellular locations of this protein?
Nucleus.
Protein: ELOA1_DROME
Sequence: MASTSNLLDVVRHYQRSIEKHGEDEQRLLHCITKLFNLPIKFEHLQETGIGKTVNALRKISGEVGVAAKTLVTKWKAMVAKEDPSIASTPTAIHNEEDSGKTKSSDEDPDQENKGGNSSSGEDLNTSKHKSKHAKSTKHERSSSSRSHSKSRSDSDKKHKSSRHDKSKDRDKDREGQKEAKEHKEKKSNGEHKSKDSSKSSSSHKSSKSESHKSEHTKSKHEKDKTSHSELKEVKDKSSKHKSSSSKSSKRSHSPPRHEEESQKAKIPKVKSKSEEDSADGFDSSMGANFDDVLGLLNIPISSKKSSSNSKSKFVAKPTAAPSSSALSAPTTAGSSKEALSTSSRPTSKKPELLASTAKLEPLDPNIALELPTISNNYKPMPLNQTVMDVVFNQGGSHKAQASRYFNESEALAQGISSKTMRTKIYSGVRTGQILQVPSLFDLCTRVLQKNIDALEYTGGVPFEVLRPVLERATPQQLLNFEEYNPYLMDDSDVLWQQHVQRHCRSQRREEMETWREMFLRCQEEKDRKLSILAESIKASQKISEAPVRKTQLAFVDSMVKPPRSVQRKQEQYGTKGKLIATPAARVAALSSVTPNAAKVGDARLRVLAAARDTAQVGAGPARSKKAPLMAKTLQFMRGRLKR
What is the function of this protein?
SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites.  Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).  May play an important role in metamorphosis.
What are the official names of this protein?
Transcription elongation factor B polypeptide 3, Elongin-A, RNA polymerase II transcription factor SIII subunit A, dEloA.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPTA_METM7
Sequence: MQCNDVQATEPDIKVSLTRVGVTNLKKLVKLKRTNKRDIVLLPTFEVFVDLPSSQKGIHMSRSPEVIEEVVENILLEKEIYGVEDLSVEIVMKLFEKHEYATRAEVMLYSDYMMEETSPVTQKDSQEIAKIMARAYGVKDDCGKIHVKKMVGAEVVGITACPCAQNMLKENAVTSLKEKGFSSEDIEKILDSVTIATHNQRGIGTVMIEVPSGYTVGISKIIKIIKDSMSGEVYELLKRSDEAYVVEMAHKNPKFVEDCAREMIKRVVDVFDYLPEDTQVLVRQVNKESIHRHDAFAERNSTIRELRDELKTLTN
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA, GTP cyclohydrolase IV.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: MAK3_ARATH
Sequence: MEKEMEDKEEFDEGEIEYTSYAGEHHLPLIMSLVDQELSEPYSIFTYRYFVYLWPQLCFLAFHKGKCVGTIVCKMGDHRQTFRGYIAMLVVIKPYRGRGIASELVTRAIKAMMESGCEEVTLEAEVSNKGALALYGRLGFIRAKRLYHYYLNGMDAFRLKLLFPKPRVPQIPSQVQTQQEYETFPRPRVP
What is the function of this protein?
Probably required for N-acetylation of some chloroplast precursor proteins and efficient accumulation of thylakoid multiprotein complexes.  In yeast, can replace the NatC complex (composed of MAK3, MAK10 and MAK31) by acetylating N termini of endogenous proteins and the N-terminus Met of L-A virus Gag protein.  However, the formation of a NatC complex is not required for this function.
What are the official names of this protein?
N-alpha-acetyltransferase MAK3, N-acetyltransferase MAK3 homolog, AtMAK3, Protein PHOTOSYNTHESIS ALTERED MUTANT 21.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MAK3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK2_PIG
Sequence: MSLSKKLTLDKLDVKGKRVIMRVDFNVPMKRNQVTNNQRIKASLPSIRYCLDNGARSVVLMSHLGRPDGVAMPDKYSLEPVAAELKSLLGKDVLFLKDCVGSEAEQACANPPAGSVILLENLRFHVEEEGKGQDPSGNKLKAEPDKVEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKASGFLMKKELDYFAKALENPERPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGMAFTFLKVLNNMEIGASLFDKEGATIVKEIMAKAEKNRVNITFPVDFVIADKFEENAKVGQATVASGIPAGWVALDCGPETNKKYAQVVARAKLIVWNGPLGVFEWDAFANGTKALMDEIVKATSKGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVEALSNL
What is the function of this protein?
Essential for sperm motility and male fertility but is not required for the completion of spermatogenesis.
What are the official names of this protein?
Phosphoglycerate kinase 2, Phosphoglycerate kinase, testis specific.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KBAZ_SHIFL
Sequence: MKHLTEMVRQHKAGKTNAIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCREHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLENVMLDRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGELQPTPRELIINHIQDILAQYHTACEGQ
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of KbaY.  When expressed alone, KbaZ does not show any aldolase activity.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit KbaZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. KbaZ subfamily.
Protein: XYL1_ASPNG
Sequence: MASPTVKLNSGYDMPLVGFGLWKVNNDTCADQIYHAIKEGYRLFDGACDYGNEVEAGQGIARAIKDGLVKREELFIVSKLWNSFHDGDRVEPICRKQLADWGIDYFDLYIVHFPISLKYVDPAVRYPPGWKSEKDELEFGNATIQETWTAMESLVDKKLARSIGISNFSAQLVMDLLRYARIRPATLQIEHHPYLTQTRLVEYAQKEGLTVTAYSSFGPLSFLELSVQNAVDSPPLFEHQLVKSIAEKHGRTPAQVLLRWATQRGIAVIPKSNNPQRLKQNLDVTGWNLEEEEIKAISGLDRGLRFNDPLGYGLYAPIF
What is the function of this protein?
Catalyzes the initial reaction in the xylose utilization pathway by reducing D-xylose into xylitol.  Xylose is a major component of hemicelluloses such as xylan.  Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway (By similarity).
What are the official names of this protein?
NAD(P)H-dependent D-xylose reductase xyl1, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: RS4_PSET1
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKLETAPGQHGARKGRLSDYGLQLREKQKVRRIYGVLEKQFRNYYKEAARLKGNTGENLLQLLEQRLDNVVYRMGFASTRAEARQLVSHKAILVNGRVVNVPSYVIAPEDTVVIREKSKTQARIIAALELAEQREKPTWVEVDGKKLEGSFKRLPERSDLSADINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RS4_CAMC5
Sequence: MARYTGPVEKLERRLGVSLALKGERRLAGKSALDKRPYAPGQHGQRRAKISEYGLQLREKQKAKFMYGISEKQFRRLFQEAARREGNTGALLVQLLEQRLDNVVYRMGFATTRRFARQLVTHGHILVNGKRVDIPSYRVEPGSKVEVIEKSKNNPQIVRAIDLTAQTGIVGWVDVEKDKKFGIFTRNPEREEVIIPIEERFIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YLAF_BACSU
Sequence: MKKMNWLLLLFAFAAVFSIMLIGVFIAEKSPAGIIASIVLVCAVMGGGFTLKKKMREQGLLD
What are the official names of this protein?
Uncharacterized protein YlaF.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRCA_SHISS
Sequence: MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: NU3M_PERGO
Sequence: MNMLMALMVNITLSILLITVAFWLPQLNMYTEKANPYECGFDPMSSARLPFSMKFFLVAITFLLYDLEIALLLPLPWAIQMYNTNTMMLTAFILVSVLALGLAYEWTQKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1711_STAES
Sequence: MRDLQQLLDELKDMSFFNPGEMCIIGCSTSEVIGKRIGSVGSMDVAKEIYENLKQLEIDTGVTFAFQGCEHINRAVTIERANFNPLTMEEVTVVPDVHAGGSLSTYAYQQMEDPIVVEHITVSKGIDIGQTLIGMHIKHVCVPVRTSVKQIGEAIVTIATSRPKKIGGERAKYQ
What are the official names of this protein?
UPF0340 protein SE_1711.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: RK22_NICSY
Sequence: MLKKKKTEVYALGEHISMSADKARRVINQIRGRSYEETLMILELMPYRACYPILKLIYSAAANASYNMGSSEANLVISKAEVNGGTTVKKLKPRARGRSFPIKRSTCHITIVMKDISLDDEYVEMYSLKKTRWKKKSTAMPYRDMYNSGGLWDKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLMM_MARMS
Sequence: MRKYFGTDGIRGKVGTTPITPEFMLKLGWAAGQVFKENDKKILIGKDTRISGYMFESALESGIVAAGADVRLVGPMPTPAIAYLTRTFRASAGIVISASHNPYTDNGIKFFSAEGGKISDELEERIEYFLEQPMEVVESSQIGRAKRIDDAAGRYIEYCKGTFPIGLQLSGLKIVVDCADGATYHVAPRVFSELGAEVISIGVNPDGLNINEFSGATKPELLRKNVLAEEADLGIALDGDGDRLILVDRHGVVRDGDDILYIIANHLMRTGRFSGGVVGTLMSNFGLELAFSETGIGFSRAAVGDRYVNEKLMQHGWVLGGEPSGHIVCRSITTTGDGIIAALQVLRAMVEEGKALDELLVGLVKFPQKLKNIRVAKRFVPNEEPTLQKAIAVANERLNGLGRVLLRASGTEPLIRVMVEGRDNDTVDELVEYLVEEVNSVVSAKADT
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: PYRG_PROMP
Sequence: MSKFVFVTGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYLNVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTAMTRLNSVTTGSIYQAVINKERRGSYNGGTVQVIPHITREIRERIHRVAANSNADIVITEIGGTVGDIESLPFLEAIREFKNDVNKNDVAYIHVTLLPYIKTSGEIKTKPTQHSVKELRSIGIQPDLLVCRSDKEINEGLKRKLSGFCGVNLNCVIEALDADSIYSVPLSLKNEGLCKQTLNCLELEDKECDLENWEKIIHNLRNPGNPIKVALVGKYIELGDAYLSVVEALRHACIEQKALLDLYWISAEMIEEKSAEEYLNDVDAIVVPGGFGNRGVNGKIEAIKFAREKNIPFLGLCLGMQCAVIEWARNIAQLPDASSSELNPDSENPVIHLLPEQEDIVDLGGTMRLGVYPCRLQKNTTGKELYNEDVIYERHRHRYEFNNYYKQSFLDSGYKISGTSPDGRLVELIELVDHPYFLACQYHPEFLSRPGKPHPLFKGLIKASQEKLEQSN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RL5_AROAE
Sequence: MARLQEFYKETVAPDLLKQFGYKSVMEVPRITKITLNMGVGEAVGDKKILEHAVGDMVKIAGQKPVVTKARKSIAGFKIRDGYPIGCMVTLRGAKMFEFLDRLVTVAMPRIRDFRGIGGKGFDGRGNYNLGVKEQIIFPEIEYDKIDALRGMNISITTTAKSDQEARALLVAFKFPFKN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: SSRP_YERPN
Sequence: MTKKKAYKPGSATIAQNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVMFKNGEAFLFGATITPLNVASTHVVCEPMRTRKLLLNKRELDSLFGRVNREGYTVVALSMYWKNAWVKVKIGVAKGKKDNDKRDDIRDREWKLDKARIMKHANR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: CEP78_HUMAN
Sequence: MIDSVKLRRDSAADFFSHYEYLCALQNSVPLPAVRACLREGVLDFNADRLRGVDWAPLLSTLKINKDLPLVSIKSFFQPWLGDTGSDMNKFCRSRVPAIRYKDVTFQLCKALKGCLSISSVLKNLELNGLILRERDLTILAKGLNKSASLVHLSLANCPIGDGGLEIICQGIKSSITLKTVNFTGCNLTWQGADHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDLGACAFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDIRKNPLIDHSMMKAVIKKVLQNGRSAKSEYQWITSPSVKEPSKTAKQKRRTIILGSGHKGKATIRIGLATKKPVSSGRKHSLGKEYYAPAPLPPGVSGFLPWRTAERAKRHRGFPLIKTRDICNQLQQPGFPVTVTVESPSSSEVEEVDDSSESVHEVPEKTSIEQEALQEKLEECLKQLKEERVIRLKVDKRVSELEHENAQLRNINFSLSEALHAQSLTNMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFQLLGHPQMTSTVSNPPKEEKKALEDEKPEPKQNALGQMQNIQFQKITGDARIPLPLDSFPVPVSTPEGLGTSSNNLGVPATEQRQESFEGFIARMCSPSPDATSGTGSQRKEEELSRNSRSSSEKKTKTESH
What is the function of this protein?
May be required for efficient PLK4 centrosomal localization and PLK4-induced overduplication of centrioles (PubMed:27246242).  May play a role in cilium biogenesis (PubMed:27588451).
What are the official names of this protein?
Centrosomal protein of 78 kDa, Cep78.
What is the protein family that this protein belongs to?
Belongs to the CEP78 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Mainly localizes at the centriolar wall, but also found in the pericentriolar material (PubMed:27246242). Expressed in photoreceptor inner segment (PubMed:27588452).
Protein: RL16_CLOB8
Sequence: MLMPKRVKHRKVQRGRMKGKATRGNFLAYGDYGIQALTCGWITSNQIESARIAINRYIKRGGKLWIKIFPDKPVTEKPAETRMGSGKGSPEYWVAVVKPGRVLFELSGVPEETAREAMRLASHKLPVKTKFVSKRDFEEMGGEE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MASZ_MYCLE
Sequence: MTDRVSAGNLRVARVLYDFVNNEALPGTDINPNSFWSGVAKVVADLTPQNQSLLNSRDELQAQIDKWHRHRVIEPFDVDAYRQFLIDIGYLLPEPDDFTISTSGVDDEITMTAGPQLVVPVLNARFALNAANARWGSLYDALYGTDTIPETEGAEKGSEYNKIRGDKVIAYARKFMDQAVPLASDSWTNATGVSIFDGQLQIAIGTNSTGLASPEKFVGYNRQLRSSNWSVLLANHGLHIEVLIDPESPIGKTDPVGIKDVILESAITTIMDFEDSVTAVDADDKVRGYRNWLGLNKGDLTEEVNKDGKTFTRVLNADRSYTTPDGGELTLPGRSLLFVRNVGHLTTSDAILVDGGDGQEKEVFEGIIDAVFTGLAAIHGLKTGEANGPLTNSRTGSIYIVKPKMHGPAEVAFTCELFSRVEDVLGLPQGTLKVGIMDEERRTTLNLKACIKAAADRVVFINTGFLDRTGDEIHTSMEAGPMIRKGAMKNSTWIKAYEDANVDIGLAAGFKGKAQIGKGMWAMTELMADMVEQKIGQPKAGATTAWVPSPTAATLHAMHYHQVDVAAVQQELTGQRRATVDQLLTIPLAKKLAWAPEEIREEVDNDCQSILGYVVRWVDQGIGCSKVPDIHNVALMEDRATLRISSQLLANWLRHGVITSEDVRASLERMAPLVDQQNAEDPAYRPMAPNFDDSIAFLAAQELILSGAQQPNGYTEPILHRRRREFKAQNR
What is the function of this protein?
Involved in the glycolate utilization.  Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
What are the official names of this protein?
Malate synthase G.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family. GlcB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA31_ARATH
Sequence: MADEKENCVRMTRAATKRKASMEAAIDKERINKKRVVLGELPNLSNIKKSRKATTKQKKKSVSIPTIETLNSDIDTRSDDPQMCGPYVTSIFEYLRQLEVKSRPLVDYIEKIQKDVTSNMRGVLVDWLVEVAEEYKLLSDTLYLAVSYIDRFLSLKTVNKQRLQLLGVTSMLIASKYEEITPPNVDDFCYITDNTYTKQEIVKMEADILLALQFELGNPTSNTFLRRFTRVAQEDFEMSHLQMEFLCSYLSELSMLDYQSVKFLPSTVAASAVFLARFIIRPKQHPWNVMLEEYTRYKAGDLKECVAMIHDLYLSRKCGALEAIREKYKQHKFKCVATMPVSPELPLTVFEDVNI
What are the official names of this protein?
Putative cyclin-A3-1, G2/mitotic-specific cyclin-A3-1, CycA3;1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: MPG1_SCHPO
Sequence: MKALILVGGFGTRLRPLTLTLPKPLVEFGNKPMILHQVEALAAAGVTDIVLAVNYRPEIMVEALKKYEKEYNVNITFSVENEPLGTAGPLALARDILAKDHSPFFVLNSDVICEYPFADLAAFHKAHGAEGTIVVTKVEEPSKYGVVVHYPNSESLIERFVEKPVEFVSNRINGGIYILNPSVLDRIEPRPTSIEKEVFPAMVNDKQLHSFDLEGYWMDVGQPKDYLTGTCLYLSSLRKHKPEILAPASSNIIGNVLIDPSATIGKNCKIGPNVVIGPNVTIGDGVRLQRCAILKSSRVRDHAWVKSSIVGWNSTLGSWSRLENVSVLGDDVVVNDEIYVNGGSILPHKSISANIEVPGTIVM
What is the function of this protein?
Involved in cell wall synthesis where it is required for glycosylation.  Involved in cell cycle progression through cell-size checkpoint.  Required for the correct assembly of the septum.
What are the official names of this protein?
Mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosphorylase, GTP-mannose-1-phosphate guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMP19_HUMAN
Sequence: MNCQQLWLGFLLPMTVSGRVLGLAEVAPVDYLSQYGYLQKPLEGSNNFKPEDITEALRAFQEASELPVSGQLDDATRARMRQPRCGLEDPFNQKTLKYLLLGRWRKKHLTFRILNLPSTLPPHTARAALRQAFQDWSNVAPLTFQEVQAGAADIRLSFHGRQSSYCSNTFDGPGRVLAHADIPELGSVHFDEDEFWTEGTYRGVNLRIIAAHEVGHALGLGHSRYSQALMAPVYEGYRPHFKLHPDDVAGIQALYGKKSPVIRDEEEEETELPTVPPVPTEPSPMPDPCSSELDAMMLGPRGKTYAFKGDYVWTVSDSGPGPLFRVSALWEGLPGNLDAAVYSPRTQWIHFFKGDKVWRYINFKMSPGFPKKLNRVEPNLDAALYWPLNQKVFLFKGSGYWQWDELARTDFSSYPKPIKGLFTGVPNQPSAAMSWQDGRVYFFKGKVYWRLNQQLRVEKGYPRNISHNWMHCRPRTIDTTPSGGNTTPSGTGITLDTTLSATETTFEY
What is the function of this protein?
Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease).  May also play a role in neovascularization or angiogenesis.  Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
What are the official names of this protein?
Matrix metalloproteinase-19, MMP-19, Matrix metalloproteinase RASI, Matrix metalloproteinase-18, MMP-18.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.