PharMolix/UniProtQA huggingface dataset:
Protein: EFTS_YERPE
Sequence: MVAITAALVKELRERTAAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRIAAEGIILAKVSADGKYGVILELNCETDFVAKDAGFKAFGEEVINAALAEKIADIDVLKAKFEEQRANLVAKIGENINIRRVAVLEGDILGTYLHGARIGVMVAATGADEELVKHIAMHIAASKPEYVKPDDVPAEVVAREHQIQLDIAIESGKPREIAEKMVEGRMRKFTGEVSLTGQNFVMDPSKTVGDLLKENNADVVNFIRFEVGEGIEKVETDFAAEVAAMSKQS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_DIPAN
Sequence: MNGTEGPFFYVPMVNTTGIVRSPYEYPQYYLVNPAAYAALGAYMFLLILVGFPINFLTLYVTIEHKKLRTPLNYILLNLAVADLFMVLGGFTTTMYTSMHGYFVLGRLGCNIEGFFATLGGEIALWSLVVLAIERWVVVCKPISNFRFGENHAIMGLAFTWTMAMACAAPPLVGWSRYIPEGMQCSCGIDYYTRAEGFNNESFVIYMFICHFTIPLTVVFFCYGRLLCAVKEAAAAQQESETTQRAEKEVTRMVIMMVIAFLVCWLPYASVAWYIFTHQGSEFGPVFMTIPAFFAKSSSIYNPMIYICLNKQFRHCMITTLCCGKNPFEEEEGASTASKTEASSVSSSSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: CT52_CONMR
Sequence: MRCVPVFVILLLLIASAPTVDAQLKTKDDMPLASFHANVKRTLQILRDKRFCCRTQEVCCEAIKNG
What are the official names of this protein?
Conotoxin mr5.2, Gla-MrIII.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIMP_METPP
Sequence: MSWQAAVEKTVTGFGYELVECERGSQGLLRVFIDRVPGQVYDGGPGEFVTVEDCEKVTRQLQYVLEVENCDYSRLEVSSPGLDRPLKKSADYARFAGERIDITLKLPFQGRKKYQGVLAASGEAWELHFNDGKQDQVLGFTLEEVRDARLVPVVDFKGRKGKEPAEPAAQVPGGYEQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_NICSY
Sequence: MLGDGNEGISTIPGFNQIQFEGFCRFIDQGLTEELYKFPKIEDTDQEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKNSRDMQEQTIFIGNIPLMNSLGTSIVNGIYRIVINQILQSPGIYYRSELDHNGISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVLSSAMGLNLREILENVCYPEIFLSFLSDKERKKIGSKENAILEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNRRLNLDIPQNNTFLLPRDILAAADHLIGLKFGMGALDDMNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKLIPTPQNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGHWGSLESPFYEISERSTGVRMLYLSPGRDEYYMVAAGNSLALNQDIQEEQVVPARYRQEFLTIAWEQVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQAALDSGALAIAEREGRVVYTNTDKILLAGNGDILSIPLVIYQRSNKNTCMHQKLQVPRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNSEDAVLISERLVYEDIYTSFHIRKYEIQTHVTSQGPEKVTNEIPHLEAHLLRNLDKNGIVMLGSWVETGDILVGKLTPQVVKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWIQKRGGSSYNPETIRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRSVDMVFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGNPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPNPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CSA5A_SACS2
Sequence: MEASEPVAETISKRFWTLIKMLRFYVVLRRFGYIDPLIYSIDPKQIKDVLSEALREFVSYTSSSSSRSIVIYDDPKNPVTAQAPCLVVAKRDEIPQNFPSIYRYTIYKIDKSSEYCISPLVVNDKYATLITPNESVIKEFFDKLDSNIQYARVLASLAVGGE
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
What are the official names of this protein?
CRISPR type I-A cluster 1/Apern-associated protein Csa5-1.
Protein: NUPR1_MOUSE
Sequence: MATLPPTANPSQQPLNLEDEDGILDEYDQYSLAHPCVVGGGRKGRTKREAAANTNRPSPGGHERKLLTKFQNSERKKAWR
What is the function of this protein?
Transcription regulator that converts stress signals into a program of gene expression that empowers cells with resistance to the stress induced by a change in their microenvironment.  Thereby participates in regulation of many process namely cell-cycle, apoptosis, autophagy and DNA repair responses (PubMed:11896600, PubMed:19723804, PubMed:23900510, PubMed:27451286, PubMed:22565310, PubMed:20181828).  Controls cell cycle progression and protects cells from genotoxic stress induced by doxorubicin through the complex formation with TP53 and EP300 that binds CDKN1A promoter leading to transcriptional induction of CDKN1A (By similarity).  Protects pancreatic cancer cells from stress-induced cell death by binding the RELB promoter and activating its transcription, leading to IER3 transactivation (PubMed:22565310).  Negatively regulates apoptosis through interaction with PTMA (By similarity).  Inhibits autophagy-induced apoptosis in cardiac cells through FOXO3 interaction, inducing cytoplasmic translocation of FOXO3 thereby preventing the FOXO3 association with the pro-autophagic BNIP3 promoter (PubMed:20181828).  Inhibits cell growth and facilitates programmed cell death by apoptosis after adriamycin-induced DNA damage through transactivation of TP53 (PubMed:11896600).  Regulates methamphetamine-induced apoptosis and autophagy through DDIT3-mediated endoplasmic reticulum stress pathway (By similarity).  Participates in DNA repair following gamma-irradiation by facilitating DNA access of the transcription machinery through interaction with MSL1 leading to inhibition of histone H4' Lys-16' acetylation (H4K16ac) (By similarity).  Coactivator of PAX2 transcription factor activity, both by recruiting the EP300 cofactor to increase PAX2 transcription factor activity and by binding PAXIP1 to suppress PAXIP1-induced inhibition on PAX2 (By similarity).  Positively regulates cell cycle progression through interaction with COPS5 inducing cytoplasmic translocation of CDKN1B leading to the CDKN1B degradation (By similarity).  Coordinates, through its interaction with EP300, the assiociation of MYOD1, EP300 and DDX5 to the MYOG promoter, leading to inhibition of cell-cycle progression and myogenic differentiation promotion (PubMed:19723804).  Negatively regulates beta cell proliferation via inhibition of cell-cycle regulatory genes expression through the suppression of their promoter activities (PubMed:23900510).  Also required for LHB expression and ovarian maturation (PubMed:18495683).  Exacerbates CNS inflammation and demyelination upon cuprizone treatment (PubMed:16374777).
What are the official names of this protein?
Nuclear protein 1, Protein p8.
What is the protein family that this protein belongs to?
Belongs to the NUPR family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, perinuclear region.
Protein: NUOD2_SINMW
Sequence: MTEVTELMRPEGEALNTKEVLLNLGPQHPSTHGVLRLVLQLDGEYVERIDPHIGYLHRGTEKLAESFTYTQIFPLTDRLDYLCPPSNNLAFALAVEKLLGIEAPIRAQYIRVMMAELARISGHLLITGALPMDLGAMTALLYAMREREMIMDLLEMITGARMHTSYCRVGGVREDLPDGFLPKIREFCEIFPNRIRDYERLIENNRVFLSRTQGIGVISAADAVDLGLSGPNLRASGVDWDIRRDEPYEIYDRLDFDVITREEGDCYARWLCRVDEMRESIRLIEQCMEQMPEGPFQVDIPTIAFPVDKERVHCSMEALIQHFDLSAYGFDVPAGEVYSVIEAPKGELGFYIISDGSPKPFRMKVRAPSFVNLQALFGVTNARYLADMIAVLGSLDPVMAEVDK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D 2, NADH dehydrogenase I subunit D 2, NDH-1 subunit D 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SELO_PSE14
Sequence: MKALDELIFDNRFARLGDAFSTSVLSEPIETPRLVVASQSALALLDLAPEQADLPLFAEIFSGHKLWSEAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEAYNDAGEHWDLHLKGAGRTPYSRMGDGRAVLRSSIREFLASEALHALGIPSSRAGCVVSSSTPVWRETQEHAAMVLRLAQSHVRFGSLEYFFYTKQPEQLKTLAEHVLTMHYPHCQEQPEPYLAMFREIVERNAELIAKWQAYGFCHGVMNTDNMSILGITFDFGPFAFLDDFDEHFICNHSDHEGRYSFSNQVPIAQWNLSALAQALTPFISVEALRETIGLFLPLYQAHYLDLMRRRLGLTIAQEQDEQLVSQLLKLMQNSGVDYTLFFRRLGDQPAAEALRTLRDDFVDIKGFDGWAEAYLARIAGEGKGTEQERQTRMHAVNPLYILRNYLAQNAIAAAEKGDYAEVRRLHQVLCTPFTEQPGMEGYAQRPPDWGKHLEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ISPD_VIBVY
Sequence: MARSMTSLVAVVPAAGVGSRMKADRPKQYLQIHGKTILEHTIERLLSHPAITQVVVAVSEDDPYYSDLAIAQHPDIIRVAGGKERADSVLSALCFLSQQPQKTDWVLVHDAARPCVAHQDIDALIERCSSHETGGILATPVRDTMKRANAQQMIDHTVDRNALWHALTPQMFKAEVLTDALSDALAQGVAITDEASALEWRGALPALVQGCSSNIKVTQPEDLALAEFYLSREKDRK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: ABHDB_BOVIN
Sequence: MLRWTRAWTAPYRGIGLSNSSFSRLPIAPSSSQGGTEPRPVRLSYKLLDGEAASPALVFLHGLFGSKTNFNFVAKTLAQQTGRRVLTVDARNHGESSHSPDMSYEAMSKDLQDLLPHLGLVPCVLIGHSMGGRTAMLLALQRPELVERLIAVDISQVETTSSSNFPNYIAAMRAVDMANEASLSGARKLADERLRSVIQSASIRQLLLTNLVEVDGRFVWRLNLDALAQHLDKILDFPARQETYSGPTLFLRGGNSQFLLPSHYPEIRRLFPRAQMQTVPNAGHWVHSDRPQDFMAAVQSFLA
What are the official names of this protein?
Protein ABHD11, Alpha/beta hydrolase domain-containing protein 11, Abhydrolase domain-containing protein 11.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: RL282_NOCFA
Sequence: MSAHCQVTGRKPGFGKSVSHSHVRTNRRWDPNIQRKTYYLPSEGRRITLTVSAKGIKTIDRDGIEAVVARLRARGEKI
What are the official names of this protein?
50S ribosomal protein L28 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: CRVP_PROJR
Sequence: MIAFIVLPILAAVLQQSSGNVDFDSESPRKPEIQNEIIDLHNSLRRSVNPTASNMLKMEWYPEAAANAERWAYGCIESHSSRDSRVIEGIKCGENIYMSPYPMKWTDIIHAWHGEYKDFKYGVGAVPSDAVVGHYTQIVWYKSYRIGCAAAYCPSAEYSYFYVCQYCPAGNMIGKTATPYTSGPPCGDCPSDCDNGLCTNPCRQENKFTNCDSLVRQSSCQDNYMKTNCPASCFCHNEII
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein, TJ-CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIE_SALRD
Sequence: MENTSTNGEPARAEKSIGRLHVLTDFHLQQDRSHAELARLAIRGGADTIQFRQKHGGIQNKLLEARKVATVCADASTPLLIDDHLDIAQATDADGVHLGQDDFPIDAARSVLGPSPIIGGTASKPHEAAEAYEQGADYIGFGPVFPTTSKRNPKSVKGPDGLADACEAVPIPVIAIGGITHDRVRSVLEAGAHGVAVLSAVDTARNPEQATARFRAAIDGVLREADS
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: YTCA_ECOLI
Sequence: MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWFFCAIASLILTLITRRVIQRANINLAFVGIIYTALFALYAMLFWLAFF
What are the official names of this protein?
Uncharacterized protein YtcA.
What is the protein family that this protein belongs to?
Belongs to the YtcA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Membrane; Multi-pass membrane protein.
Protein: LEUD_PSET1
Sequence: MSIYFSGLMAPLDKNNVDTDQIIPKQFLTSTSREGFDAALFYDWRYLENDEPNPDFILNRPCYQGAQILLTRDNFGCGSSREHAPWALKQYGFEVILAESFADIFFNNCGNNQMLAIALPGDTLEQLFVLSEQHDDIHIDIDLENQTLTSTKFAPISFDIRKDVKERLLSGLDFIGVTETLNPQIDAFEQQLAAERPWQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RS12_SULSY
Sequence: MPTINQLVRKGREKVEKKSKAPALQGNPQKRGVCVRVYTTTPKKPNSALRKVARVRLSNGYEVTCYIPGIGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGALDAAGVKDRKQSRSKYGAKRPKPGQAAATTGKKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DPOL_HBVOR
Sequence: MPLSCQHFRKLLLLDEEAGPLEEELPRLADEGLNHRVAEDLNLQLPNVSIPWTHKVGNFTGLYSSTAPVFNPNWQTPSFPDIHLHQDIINKCEQLVGPLTVNEKRRLKLIMPARFYPNSTKYFPPDKGIKPYYPEHGVNHYFQARHYLHTLWKAGVLYKRETTRSASFCGSPYSWEQELQHGAEPFCHQPFGILPRASIGPAVPSQHKQSRLGLQSQQGHLARSHQGRSGSIWARVHSTSRRSFGVEPAGSGRNHNTASSSSSCLHQSAVRKAAYSHLSTFERHSSSGHAVELHGFPPSSAGSQSKGSVFPCWWLQFRDSEPCSDNCLSHIVNLLEDWGPCTEHGEHLIRIPRTPARVTGGVFLVDKNPHNSSESRLVVDFSQFSRGSTRVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLPRYVARLSSTSRNHHHQRGTMQNLHDFCSRNLFVSLMLLYKTFGRKLHLYSHPTIMGFRKIPMGVGLSPFLLAQFTSALCSVVRRAFPHCLAFSYMDDMVLGAKSVQHLESLYTAVTNFLLSLGIHLNPGKTKRWGYSLHFMGYVIGSWGTLPQDHIVQKIKQCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYNCIHNRQAFTFSPTYKAFLRTQYLTLYPVARQRPGLCQVFADATPTGWGLALGPQRMRGTFVAPLPIHTAELLAACFARSRSGANIIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLRLPFRPTTGRTSLYAVSPSVPSHLPVRVHFASPLHVAWRPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: ARGJ_THEMA
Sequence: MFTPRGFKFAGVHCKIKRKRKDLGIIFSEVPCVAAGVFTTNVVKAAPVIYDMEILKKNPNGIKAVVVNSGVANACTGEQGMINARRMAEKTAEELGVPVESVLVSSTGVIGVQLPMDKVENGIEEAARVLSNDPLPFAEAIMTTDTKVKMHSTKVMIDGKEITVLGIAKGSGMIHPNMATMLSFITTDAKISEEALKKLLKLSVDDSYNMIDVDGDTSTNDMVIVLANGLAGNTTIQPETDGFWKLYEAVHEVNQVLAEKIVEDGEGATKVMEVHVINAPDIKSARLIARSIVSSNLVKTAIYGEDANWGRVIAAAGYSGATFDPEKLDLFFESEAGRIKVAENGQGVSFDEEEAKKILSEKKIRIILDMKQGKETAKAWGCDLTEKYVEINGRYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_YERPB
Sequence: MSWFTPELIEILISVLKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWVPRFSDRAIFTLAPVIAFTSLLLSFAIVPVSPTWAVADLNIGILFFLMMAGLAVYAVLFAGWASNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMQDIVNSQEHVWNVIPQFFGFLTFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTVSALIVTLFFGGWQGPFLPPFIWFALKTAFFMVMFILIRASLPRPRYDQVMSFGWKVCLPLTLLNLLATAAVILYNAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REX_PEDPA
Sequence: MDDNKISLATTRRLPLYYRCLSELNEKGEDKVSSAVLERLLKIDAATVRRDFSYFGQMGRRGYGYDVKILLELFNDVLKQDTAANVAIVGVGNLGHALINFKFHKTGNARIKMAFDVNPEVVGTIQSEVPVYDINEIKQRVRDEKIEVAILTVPNSQAQRVTDLLVEAGIKGIMNFTTEIIDVPYNVTIHDVDLSLELQALIYSMDQD
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLL_SYNS3
Sequence: MTTTLTRPADGDGSVQVHQDPGTKIEEGALVIAVYGKGGIGKSTTSSNLSAAFSKLGKRVLQIGCDPKHDSTFTLTHKMVPTVIDILEEVDFHSEELRPEDFMFTGYNGVKCVESGGPPAGTGCGGYVTGQTVKLLKEHHLLEDTDVVIFDVLGDVVCGGFAAPLQHANYCLIVTANDFDSIFAMNRIVQAIQAKAKNYKVRLGGVVANRSAETDQIDKFNERTGLRTMAHFKDVDAIRRSRLKKCTIFEMDDKDDGVKAVQDEYIRLASNMLNNVEPLEAVSLKDREIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.
Protein: CPFC_ANOFW
Sequence: MSKKVMGLLVMAYGTPYKEEDLERYYTHIRHGRKPSEEMLADLRERYEAIGGISPLAAITKQQAEKLAERLNEVQDEIEFRMYLGLKHIEPFVEDAVQQMHEDGIEEAVSIVLAPHFSTFSVKSYNGRAKEEAARLGGPKLTCVESWYTEPKFIQYWADRVKETYASMSEREREKAVLIVSAHSLPEKIIAMGDPYPKQLQETADFIAKEAGVSEYVIGWQSAGNTPEPWLGPDVQDLTRQLYEEKGYEAFVYVPAGFVSDHLEVLYDNDIECKQVTDELGVSYYRPPMPNAHPQFIDALATVVLNHLRKEGESL
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDK_DROME
Sequence: MRLFPVRFSAASSSMASLAKMLDFYSGFNPSPLSIKQFMDFGQNACEKKSYIFLRKELPVRLANIMKEIALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEPTHDNLQKFVADLDLIRNRHNDVVQTMAQGVIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGGNPHAGGRHIGCLDPACDLSDVVRDAYENARFLCDQYYLTSPALEIQQHSSEPGDNLPIRTVYVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSDLHTVPLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANELLPIFNKTSSKFYRATVPTGDWSNQVKYAKKKKTSAVNQ
What is the function of this protein?
Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
What are the official names of this protein?
[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial, DmPDK, Pyruvate dehydrogenase kinase.
What is the protein family that this protein belongs to?
Belongs to the PDK/BCKDK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYE_AZOPC
Sequence: MKARVRFAPSPTGPLHIGSIRTALYNYLFAKKYHGDFILRIEDTDSTRFIPGAEEYIIETFKWLGITFDEGPYRQSERKAIYKEYVDELLNKNLAYIAFDTPEELEAKRRNIPNFQYDAITRMTMNNSLTLSKEETKKRIANSNQYVVRIKIDPNQTIIVNDLIRGEMSISSSTLDDKVLYKSSDNLPTYHLANIVDDHLMKITHVIRGEEWLSSTPLHIILYQYFGWGEKMPVFAHLPLLLKPDGKGKLSKRDGERFGFPIFPLQWTDSKTGKSISGYREDGYLPEALINFLALLGWNPGSEQEFFSIDELSVLFSLKKCSKNGAKFDYKKVEWFNHQYIQKKSDKEIAELFFHFYSKKLEKQDFKKITEVIGMVKGRISSIRDLWYETAFFFVAPNTYDEKIVQKRWRAESPIQLTELSELLATITNFSLQIVEKTIRGWINNKGYHPSNIMNACRLALVGTAKGPGIFHIIEILGKEEVIIRIKKAIQVLR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.