PharMolix/UniProtQA huggingface dataset:
Protein: SECB1_FRATO
Sequence: MDQQAQPQFQIQKVYVKDLSFSIPNSDKIWTTNWKPELHTDLKVEATKLPEENTYETVLTLEVKVENDGMVAFEAEVKQAGIFTVANMQEAQIEHAKKAFCPNILYHYAREAISDLVISGGFPQLCLSAVNFDAMYQDSLKESADSKQH
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB 1.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_PLAOC
Sequence: MEKWWFNSMLSNEELEHRCGLSKSMDSLGAIGNSSGSEDPVINDTDKNIHSWSDIDSSSYSNVDHLFGVRNIRNFISDDTFLVRDRTGDSYSIYLDIENEIFEIDNDRSFLSELESYFSSYLNNRSKSDTHYYDRYMYDTKYTWNNHINSCIDSYIRSEISIDSYISSGSDNYDNYSDSYISSYICSESVINSSDSGSYSIRTSTSTNGSDFNIRGRYNDLDINKKYRHLWIQCENCYGLNYKKFFRSKMNICEQCGYHLKMSSSDRIELSIDPGTWDPMDEDMVSIDPIEFHSEEEPYKDRIDSYQRKTGLTEAVQTGIGQLNGIPIAIGVMDFQFMGGSMGSVVGEKITRLIEYATNGSLPLIIVCASGGARMQEGSLSLMQMAKISSASYDYQSNKKLFYVSILTSPTTGGVTASFGMLGDIIIAEPNAYIAFAGKRVIEQTLNKTVPEGSQAAEYSFHKGLFDSIVPRNLLKGVLSELFQLHGFFPLNQNSIK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: SEM1A_TRICF
Sequence: MVVKILVWSICLIALCHAWMPDSSSKLINHFKSVESKSFTGNATFPDHFIVLNQDETSILVGGRNRVYNLSIFDLSERKGGRIDWPSSDAHGQLCILKGKTDDDCQNYIRILYSSEPGKLVICGTNSYKPLCRTYAFKEGKYLVEKEVEGIGLCPYNPEHNSTSVSYNGQLFSATVADFSGGDPLIYREPQRTELSDLKQLNAPNFVNSVAYGDYIFFFYRETAVEYMNCGKVIYSRVARVCKDDKGGPHQSRDRWTSFLKARLNCSIPGEYPFYFDEIQSTSDIVEGRYNSDDSKKIIYGILTTPVNAIGGSAICAYQMADILRVFEGSFKHQETINSNWLPVPQNLVPEPRPGQCVRDSRILPDKNVNFIKTHSLMEDVPALFGKPVLVRVSLQYRFTAITVDPQVKTINNQYLDVLYIGTDDGKVLKAVNIPKRHAKALLYRKYRTSVHPHGAPVKQLKIAPGYGKVVVVGKDEIRLANLNHCASKTRCKDCVELQDPHCAWDAKQNLCVSIDTVTSYRFLIQDVVRGDDNKCWSPQTDKKTVIKNKPSEVENEITNSIDEKDLDSSDPLIKTGLDDDSDCDPVSENSIGGCAVRQQLVIYTAGTLHIVVVVVSIVGLFSWLYSGLSVFAKFHSDSQYPEAPFIEQHNHLERLSANQTGYLTPRANKAVNLVVKVSSSTPRPKKDNLDVSKDLNIASDGTLQKIKKTYI
What is the function of this protein?
Plays a role in growth cones guidance.
What are the official names of this protein?
Semaphorin-1A, Semaphorin-I.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PROB_BORPD
Sequence: MTADTTAVSVVASATRLVAKVGSSLVTNEGRGLDRAAVAHWAAQIAALRQQGKQVVLVSSGAIAEGMARLGWRKRPSVMHELQAAAAVGQMGLCQAYEAAFAEHGLRTAQILLTHEDLADRHRYLNARSTLFALMRLGVVPIVNENDTVVTDEIRLGDNDTLGALVTNLIEADALVILTDQRGLYDSDPRKNPDAVFVAHAQAGDPELEAMAGGAGSGIGTGGMLTKILAAKRAAHSGAHTVIASGRERNVLTRLAQGECIGTELRAVLPVWSARKQWLADHLRLRGRVVLDAGAVRALLHEGKSLLPIGVIDVQGEFERGDVVACIDPQGAECARGLINYSSADTRRILRQPSSQIARILGSMTDPELMHRDNLVVI
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYBL_SCHMA
Sequence: MLHITTMTDKAPIKTNKRLQQTQAQVNEVVDIMRVNVDKVLERDKNLSELDGRADALQAGASQFEASAGKLKRKFWWKNCKMLAVLGVLVVILIIVLIVWVVSEQKNKVEQSEHSSHHLVMDNSSHLLSEQ
What is the function of this protein?
Unknown, but synaptobrevins are presumed to be involved in targeting and fusion of synaptic vesicles with the presynaptic membrane as well as in neurotransmitter release.
What are the official names of this protein?
Synaptobrevin-like protein.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Synapse, synaptosome. Note=Neuronal synaptic vesicles.
Protein: RAPA_PSEPW
Sequence: MAQQYQPGQRWISDSEAELGLGTILAQDGRLLTVLYPATGDTRQYSLRNAPLTRVRFSPGDQITHFEGWKLTVREVEDIDGLMVYHGLDGQNQPRTLPETQLSNFIQFRLASDRLFAGQIDPLSWFSLRYNTLQHTSKQVQSSLWGLGGCRAQPIAHQLHIAREVADRSAPRVLLADEVGLGKTIEAGLVIHRQLLTGRANRVLILVPENLQHQWLVEMRRRFNLQVALFDAERFIESDASNPFEDAQLALVALEWLVEDEKAQDALFAAGWDLMVVDEAHHLVWHEDKASTEYSLVEQLAQVIPGVLLLTATPEQLGQDSHFARLRLLDPNRFHDLAAFRAESEHYRPVAEAVQELLDEGRLSPKAHATIQGFLGAEGEALLAAVSDGDSQASARLIRELLDRHGTGRVLFRNTRAAIQGFPERELHPYPLPMPEQYRDLPAGEHAELYPEVAFQAQGEVSDDERWWRFDPRVDWLIDTLKMLKRTKVLVICAHAETAMDLEDALRVRSGIPASVFHEGMSILERDRAAAYFADEEFGAQVLICSEIGSEGRNFQFAHHLVMFDLPAHPDLLEQRIGRLDRIGQKHVIQLHIPYLQEGPQERLFQWYHEALNAFLNTCPTGNALQHQFGPRLLPMLEGGDSKAWDALVAEAKGERERLEAELHSGRDRLLELNSGGAGEGQALVEDILEQDDQFALPIYMETLFDAFGIDSEDHSENALILKPSEKMLDASFPLGDDEGVTITYDRGQALSREDMQFLTWEHPMVQGGMDLVLSGSMGNTAVALIKNKALKPGTVLLELLFVSEVVAPRSLQLGRYLPPAALRCLLDANGNDLASRVAFETLNEQLESVPRASANKFVQAQRDVLAKRISGGEAKIMPTHVERVAEAQRRLAAEADEELARLTALKAVNPSVRDSEIDALRKQREDGLAMLEKAALRLEAIRVLVAG
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: LIRA3_HUMAN
Sequence: MTPILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVSGAAETLSPPQNKSDSKAGE
What is the function of this protein?
Acts as soluble receptor for class I MHC antigens.  Binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1 or LILRB2.  Binds with high affinity to the surface of monocytes, leading to abolish LPS-induced TNF-alpha production by monocytes.
What are the official names of this protein?
Leukocyte immunoglobulin-like receptor subfamily A member 3, CD85 antigen-like family member E, Immunoglobulin-like transcript 6, ILT-6, Leukocyte immunoglobulin-like receptor 4, LIR-4, Monocyte inhibitory receptor HM43/HM31.
What are the subcellular locations of this protein?
Secreted.
Protein: MY113_ARATH
Sequence: MGESPKGLRKGTWTTEEDILLRQCIDKYGEGKWHRVPLRTGLNRCRKSCRLRWLNYLKPSIKRGKLCSDEVDLVLRLHKLLGNRWSLIAGRLPGRTANDVKNYWNTHLSKKHDERCCKTKMINKNITSHPTSSAQKIDVLKPRPRSFSDKNSCNDVNILPKVDVVPLHLGLNNNYVCESSITCNKDEQKDKLININLLDGDNMWWESLLEADVLGPEATETAKGVTLPLDFEQIWARFDEETLELN
What is the function of this protein?
Transcription activator, when associated with BHLH002/EGL3/MYC146, BHLH012/MYC1, or BHLH042/TT8.
What are the official names of this protein?
Transcription factor MYB113, Myb-related protein 113, AtMYB113.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPA_CROS5
Sequence: MTDVPVSRIRNFCIIAHIDHGKSTLADRMLQMTETVAQRKMKEQFLDNMDLERERGITIKLQAARMNYRSKDGEDYVLNLIDTPGHVDFSYEVSRSLAACEGALLVVDSSQGVEAQTLANVYLALENNLEIIPILNKIDLPGSEPERVANEIEEVVGLDCTGIIKASAKAGIGVDEILESIVHLVPPPSDTVDKPLRALIFDSYYDPYRGVIVYFRVMDGTVKTGDRVRLMASGKEYEIDELGVLSPNQIEVESLHAGEVGYFAAAIKAVEDARVGDTITLAEAPAKEPLPGYTEAKPMVFCGLFPTDADQYEDLREALNRLKLNDAALSYEPETSSAMGFGFRCGFLGLLHMEIVQERLEREYDLDLITTAPSVIYRVTTIDGEVIQVDNPSLLPSPQEREKVEEPYIEVEMITPETYVGTLMELCQSRRGVFKDMRYFTLSRTSLVYELPLAEVVTDFFDQLKSRSRGYASMEYQLIGYRENPLVKLDILVNGDSVDALAMIVHRDKAYYVGRALTEKLKELIPRHQFKVPIQAAIGSKVIASEHIPALRKDVLAKCYGGDISRKKKLLQKQAKGKKRMKAIGTVDVPQEAFMAVLKLDPQ
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DXS_CAUSK
Sequence: MLALTPLLDTISSPADTRGFSVAELKQLASEVRAETIDAVSVTGGHLGAGLGVVELTVALHHVFETPKDIVIWDVGHQAYPHKILTGRRDRIKTLRQGGGLSGFTKRAESVYDPFGAAHAATSISAALGFCAARDAKGENNSVIAVIGDGSMSAGMAYEAMNAAVDTTKRLIVILNDNDMSIAPPVGGMSAYLANLVSGGAYRKVRKLGKTVVEKLPTPIRDAARKAEEYARGMVTGGTFFEELGFHYVGPIDGHDMDALVSVLNNVKHFDEKPVLVHVVTQKGKGYAPAEGAADKLHAVVKFDVVTGQQHKAAAGPPSYTKVFAQELIKHAAVDDKIMAITAAMPSGTGLDLFGKAYPERTFDVGIAEQHAVTFAAGLAADGMKPFVAIYSTFLQRGYDQVVHDVAIQRLPVRFAMDRAGLVGADGPTHAGTFDLGFMGALPGMVLMAAADEVELAHMVSTAVAIDDRPSAFRYPRGEGLGLTIPDLAAPLEIGKGRIVREGTSVAIVSLGTRLAECLKAADLLAARGLSATVADARFAKPLDVDMLLRLAREHEAIITVEEGAMGGFGAFVLQALATHGALDRGLKIRTLVLPDVFQDQDKPDLMYAQAGLDAEGILRGALSALGIDNISAAGRRA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PANC_RUBXD
Sequence: MSPATLLRSPREVRELSRRWRGEGAVVGLVPTMGALHEGHLSLVRRAWEECGRVIVSVFVNPTQFGEGEDFERYPRDLEGDRRLLAEAGCDAVFAPAVEDMYGGGTTDLASGERIFVEAGRLGELWEGEERPGHFRGVCTVVAMLFNAAEPHRAYFGEKDYQQLKVIQKMARDLLFGVEIVPCPTVREPDGLALSSRNAYLSPQERRAARALWRALEAAAGEARGGVRDARRLERAMEEVCRAEPLVRLQYAAVVDAETLQRLGELGDRPARALIAARVGETRLIDNAALP
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSB3_RAT
Sequence: MSVMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD
What is the function of this protein?
Non-catalytic component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins.  This complex plays numerous essential roles within the cell by associating with different regulatory particles.  Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins.  The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required.  Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation.  This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
What are the official names of this protein?
Proteasome subunit beta type-3, Proteasome chain 13, Proteasome component C10-II, Proteasome theta chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the cytoplasm into the nucleus following interaction with AKIRIN2, which bridges the proteasome with the nuclear import receptor IPO9.
Protein: FMQE_ASPFU
Sequence: MPEDKVEAIEHVESSRHDATVNEKAIADFLNAEKEMTTWQAVRAHRRLLLFAAYRVTHLAILPFVCASNYGYDTVSNGSSIAMPAFIMSFGAMNHATGSMYLPSIWTSLWTSMTNLGQALGSLIAGFLAERIGRRWTAVSLAILSIVGTFILVFSSTRGMLLVGKTMNGAVVGGLMAIGTTYAADVAPIKLRGALLQAIVFFGVAMQGVSLGIVRAFILDMRPLAWKIVFGIQWAFATLVLIAAFLVPESPVFYVAHGKHDKAQSALRRLHGSSDQYLHIRYGAIVHALDEERKQQSESVSWAELFKGCNLKRTITIGFIMFSTSAIGVPFLTQNIYFLITVGLNVTSVFDIGIGGFFLGCLFVMLGWLSNEGIGRRRLWLWGLIGNFLCMVTIGALGFSTTKASQLAIAVIMNVLISYGVYATVGVAWTICPEISSHRLRQYSQSVAFIVGAVGGWLFNFITPYMYNVDSGNLGAKTGFVYAGLTVVVAVISWFLVPETAGLSVEDIDRAYEMGTAPRHFKSAKATVSAESGH
What is the function of this protein?
MFS transporter; part of the gene cluster that mediates the biosynthesis of the antitumor cytotoxic peptidyl alkaloids fumiquinazolines that confer a dual-usage capability to defend against phagocytes in the environment and animal hosts (PubMed:20804163, PubMed:24612080, PubMed:33705521).  Probably involved in fumiquinazolines metabolism and transport (PubMed:24612080).
What are the official names of this protein?
MFS transporter fmqE, Fumiquinazoline biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: MGRB_ECOUT
Sequence: MKKFRWVALVVVVLACLLLWAQVFNMMCDQDVQFFSGICALNQFIPW
What is the function of this protein?
PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing.  MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway.  Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP.
What are the official names of this protein?
PhoP/PhoQ regulator MgrB.
What is the protein family that this protein belongs to?
Belongs to the MgrB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PGP_HUMAN
Sequence: MAAAEAGGDDARCVRLSAERAQALLADVDTLLFDCDGVLWRGETAVPGAPEALRALRARGKRLGFITNNSSKTRAAYAEKLRRLGFGGPAGPGASLEVFGTAYCTALYLRQRLAGAPAPKAYVLGSPALAAELEAVGVASVGVGPEPLQGEGPGDWLHAPLEPDVRAVVVGFDPHFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTILTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADLLPALQG
What is the function of this protein?
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol.  Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism.  Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity.  However, their physiological relevance is unclear (PubMed:26755581).  In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity).
What are the official names of this protein?
Glycerol-3-phosphate phosphatase, G3PP, Aspartate-based ubiquitous Mg(2+)-dependent phosphatase, AUM, Phosphoglycolate phosphatase, PGP.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: SYC_PASMU
Sequence: MLKIFNTLTREKEIFKPIHANKVGMYVCGITVYDLCHVGHGRTFVCFDVIARYLRYLGYDLTYVRNITDVDDKIIKRALENNETCNQLVEKMIAEMHKDFDALNVLRPDVEPRATHHIPEIIAMIEKLIARQHAYVSANGDVMFDVESFKEYGKLSRQNLEQLQAGARVEIVNVKKNPMDFVLWKMSKPGEPSWPSPWGEGRPGWHIECSAMNHKELGEHFDIHGGGSDLTFPHHENEIAQSCCAHSGRYVNYWIHSGMIMVDREKMSKSLGNFFTLREVLSLYDAESVRYFLLTAHYRSQLNYSEENLNLAHSALERLYTALRGTDPTAVATEGQNYLAAFREAMDDDFNTPKAISVLFEIAREINKLKNEDILKANALAARLRELAGILGLLYQDPEQFLQSGSDNDEVALIEALIKQRNDARAAKDWASADAARNKLAEMGVVLEDNVNGTTWRKQ
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_CHESB
Sequence: MSTGFFGNLQPISYEGPQSDNPLAFRHYNPDEVVLGKRLEDHLRFAVCYWHTFVWPGGDPFGGQTFERPWFGDTMERARLKADVAFELFEILGVPFFTFHDADVRPEGASYSESVARLNDIADYIAAKMEKTGVRLLWGTANLFSHRRFMAGAATNPDPDVFAYAAATVKACIDVTKRLNGENYVLWGGREGYETLLNTDLGRELDQLGRFLSMVVDYKHRIGFKGAILIEPKPQEPTKHQYDFDVGTVYGFLKRYGLEDEVKVNIEQGHALLAGHSFEHELALAATLGIFGSIDMNRNDYQSGWDTDQFPNNAPEAALAYYYILQAGGFTTGGTNFDAKLRRQSLDPEDLVAAHIGGMDICAQGLKAAARMIEDKALSGPLEERYSGWNATEAQAMLKGERSLEAIAERVARENLDPKPRSGRQEKLENIINRYV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SASA_PROM0
Sequence: MNDKKELKLILVAARNQLSSNDIKSLIAYLESDDCEFEISLQISEPTEQPELLELHRLVAIPALIKVSPAPKQIFAGSNIFSQLQKWLPRWTQEGLTKNLGINLQPSKIDSIRTQKEFLLEDELLVLRQENETLTKRIESQERLLRMVAHELRTPLTAATLAVQSQKLGQIDISKLQEVIKRRLEEIELLSQDLLEVGTTKWEALFNPQKIDLGNISAEVILELEKFWRLRNIEIDTDIPSDLPSVFADQRRMRQVFLNLIENAIKFSRDSGSIKITMIHKTNQWVEITICDKGAGIPLSEQKRIFLDRVRLPQTSEGTSGFGIGLSVCRRIVQVHGGRIWVVSEVGVGSCFHFTVPVWQGQNKEQQYLTKG
What is the function of this protein?
Member of the two-component regulatory system SasA/RpaA involved in genome-wide circadian gene expression.  One of several clock output pathways.  Participates in the Kai clock protein complex, the main circadian regulator in cyanobacteria, via its interaction with KaiC.  KaiC enhances the autophosphorylation activity of SasA, which then transfers its phosphate group to RpaA to activate it.  In addition to its output function, recruits fold-shifted KaiB (KaiB(fs)) to KaiC to cooperatively form the KaiB(6):KaiC(6) complex (independent of SasA kinase activity).  Required for robustness of the circadian rhythm of gene expression and is involved in clock output, also required for adaptation to light/dark cycles.
What are the official names of this protein?
Adaptive-response sensory kinase SasA, Sensor histidine kinase SasA.
Protein: KTHY_ECOBW
Sequence: MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGTQLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHDLSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIEQESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SYM_CHRVO
Sequence: MIRMTKRKILVTSALPYANAGLHLGHMLEQIQTDIWVRFQKMRGHECYYVCADDTHGAPIMLAAEKRGITPEQLVNEVRELHVADSQGFLIGHDNYYSTNSPENKALAEQVYLALKADDKIACRTIEQLFDPEKQMFLPDRFVKGECPKCSAKDQYGDNCEVCGATYAPTELKNPYSAVSGAKPVLKTSEHFFFRLGECADFLKAWTSGASRRADGAVQPHLQPESLNKMNEWIGGGLQDWDISRDAPYFGFEIPGAPGKYFYVWLDAPIGYMASFKNLCERLNLNFDEWFAKDSQTEMYHFIGKDILYFHALFWPAMLNYSGLRAPTGVFAHGFLTVDGQKMSKSRGTFIQAKSYLDCGLNPEWMRYYIAAKLNGRIEDIDLNLNDFVARVNSDLVGKFVNIASRSAGFIAKRFDGMLAAQVSDGEILAKLQAAAEELAAAYEAREYAKALRDVMALADIVNGYVDANKPWELAKQEGQDARLQDVCTVLVNAFRLLAIYLKPVLPKLAEGVEAFLDVAPLSWHDAETLLLGKKINAYQHLMQRIDPALIDKLIEANKQNMQAIQDAPAAAAHEPLAETIKIDDFAKVDLRVGKVLECNFVEGSDKLLQFKVDLGFETRNIFSGIRKAYQEPEKLVGRHVIVVANLAERKMRFGVSQGMIVCASGVDDSEGLFLLDVDAGVKPGMRVG
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AFSQ1_STRCO
Sequence: MPSLLLIEDDDAIRTALELSLTRQGHRVATAASGEDGLKLLREQRPDLIVLDVMLPGIDGFEVCRRIRRTDQLPIILLTARNDDIDVVVGLESGADDYVVKPVQGRVLDARIRAVLRRGERESTDSASFGSLVIDRSAMTVTKNGEDLQLTPTELRLLLELSRRPGQALSRQQLLRLVWEHDYLGDSRLVDACVQRLRAKVEDVPSSPTLIRTVRGVGYRLDPPQ
What is the function of this protein?
Forms part of a two-component regulatory system AfsQ1/AfsQ2 involved in secondary metabolism.
What are the official names of this protein?
Transcriptional regulatory protein AfsQ1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLPP1_MOUSE
Sequence: MFDKTRLPYVALDVICVLLAGLPFAILTSRHTPFQRGIFCNDDSIKYPYKEDTIPYALLGGIVIPFCIIVMSIGESLSVYFNVLHSNSFVGNPYIATIYKAVGAFLFGVSASQSLTDIAKYTIGSLRPHFLAICNPDWSKINCSDGYIEDYICQGNEEKVKEGRLSFYSGHSSFSMYCMLFVALYLQARMKGDWARLLRPMLQFGLIAFSIYVGLSRVSDYKHHWSDVTVGLIQGAAMAILVALYVSDFFKDTHSYKERKEEDPHTTLHETASSRNYSTNHEP
What is the function of this protein?
Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P (PubMed:8702556, PubMed:10359651, PubMed:10818444, PubMed:10620492, PubMed:15461590, PubMed:19215222).  Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (By similarity).  Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these bioactive lipid mediators from the milieu, regulating signal transduction in different cellular processes (PubMed:17379599).  It is for instance essential for the extracellular hydrolysis of S1P and subsequent conversion into intracellular S1P (PubMed:17379599).  Involved in the regulation of inflammation, platelets activation, cell proliferation and migration among other processes (PubMed:15461590, PubMed:17057224).  May also have an intracellular activity to regulate phospholipid-mediated signaling pathways (PubMed:17057224).
What are the official names of this protein?
Phospholipid phosphatase 1, 35 kDa PAP, mPAP, Hydrogen peroxide-inducible protein 53, Hic53, Lipid phosphate phosphohydrolase 1, PAP2-alpha, Phosphatidate phosphohydrolase type 2a, Phosphatidic acid phosphatase 2a, PAP-2a, PAP2a.
What is the protein family that this protein belongs to?
Belongs to the PA-phosphatase related phosphoesterase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein.
Protein: RL28_ACIF5
Sequence: MSRVCKVTGKKPMAGNNVSHAHNKTRRRFLPNLQYHRFWVESENRWVRMRVSTKGIRTIDKKGIDVVLADLRAAGEKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.