PharMolix/UniProtQA huggingface dataset:
Protein: CYNS_LACBS
Sequence: MSFASAPTVPTNTSHYADLPAASSALFQAKARRGLTFDQIAKAIGKDEVWLAAAFYGQARFTEDELITVGEVLGIGSSELVSQLGSHWWPNRGLGPMPPTDPVIYRLYESVLVYGHAIKAVIHEKFGDGIMSMIDCKINVERKEDPKGDRVLLTFDGKFLPYARW
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: KDPC_PARL1
Sequence: MESFIASIRLVAATMLICVAGYSAAVWAVGQVLMPGSAQGSLIAAADGKVIGSSQVAQNFTEPRYFWPRPSAVDYNGAGAGGSNKSPTSTDIADRARETVARYGATAENPLPAELAAASGAGLDPHISERGALYQAARVAQARGLPQAGVEALIHEHAFAPGAFLAPDRLVNVLELNLALDRVETAG
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HSLO_ECO7I
Sequence: MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMSLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLAA_SPIAU
Sequence: MKRFFAILGAALFVGNSGAFAEQATLIDFSKLVGEGNTGLHAPTTIDYSRQAGSAYSAEDKAAMKISLAIPSWEIELASSSQTVENQTLSLVTAAPVKQDAARYGGETVMGVRIHFPSFGINSFAVIKPPFTIPAYATLGDATAQNAVAGGQFDGFGVLKNVGVIKSIQINILGRNYLNRLSLLLEDQNGDEREIVMGYLNFDGWKSLQWNNPNYQTEVRNRDLQIVPLYPRSAPLIKLKGIKIHRDGSQEGGDIVSYIKDIKVIYDQAVVDRNSDVDDEAIWGILRQREEQYRNFELAKLGNLQVLRSLEKKKMAKEADFDQAAPAAAAARAPATN
What is the function of this protein?
Component of the outer layer of the flagella.
What are the official names of this protein?
Flagellar filament outer layer protein, Sheath protein.
What are the subcellular locations of this protein?
Periplasmic flagellum. Periplasm.
Protein: CAR4_ARATH
Sequence: MTTACPARTSSLMDDLLGLLRIRIKRGVNLAVRDISSSDPYVVVKMGKQKLKTRVINKDVNPEWNEDLTLSVTDSNLTVLLTVYDHDMFSKDDKMGDAEFEIKPYIEALRMQLDGLPSGTIVTTVKPSRRNCLAEESRVTWVDGKLVQDLVLRLRHVECGEVEAQLQWIDLPGSKGL
What is the function of this protein?
Mediates the transient calcium-dependent interaction of PYR/PYL/RCAR abscisic acid (ABA) receptors with the plasma membrane and thus regulates ABA sensitivity (PubMed:26719420, PubMed:25465408).  Stimulates the GTPase/ATPase activities of YchF1, and regulates its subcellular localization.  Promotes tolerance towards salinity stress by limiting the accumulation of reactive oxygen species (ROS) (PubMed:23550829).  Promotes resistance to bacterial pathogens (e. g.  Xanthomonas oryzae pv.  oryzae and P.  syringae pv.  tomato DC3000) (By similarity).  Binds liposomes in the absence of exogenous Ca(2+), but this activity is enhanced in the presence of Ca(2+) and generates membrane curvature (PubMed:26719420).
What are the official names of this protein?
Protein C2-DOMAIN ABA-RELATED 4, C2 domain-containing protein, AtC2, GTPase activating protein 1, AtGAP1.
What is the protein family that this protein belongs to?
Belongs to the plant CAR protein family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Cytoplasm, cytosol. Note=Localized mainly in the cytosol under NaCl treatment, but translocates to the plasma membrane upon wounding.
Protein: ILVC_PECCP
Sequence: MANYFNTLNLRQQLDQLGKCRFMGRDEFADEASYLKGKKVVIVGCGAQGLNQGLNMRDSGLDIAYALRAEAIAEKRASWRKATENGFTVGTYEDLIPQADLVVNLTPDKQHSAVVQAVQPLMKQGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLQSSFVAEVKSDLMGEQTILCGMLQAGSLLSFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKGIMAPLFQKHMDDIISGEFSSGMMADWANDDVKLLTWREETGKTAFENAPQFDGKIAEQEYFDNGVLMVAMVKAGVELAFETMVSSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKDAFMASLQPGDLGKAVAGTEVDNAQLRDVNEAIRNHPIETVGQTLRGYMKDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MYLK2_HUMAN
Sequence: MATENGAVELGIQNPSTDKAPKGPTGERPLAAGKDPGPPDPKKAPDPPTLKKDAKAPASEKGDGTLAQPSTSSQGPKGEGDRGGGPAEGSAGPPAALPQQTATPETSVKKPKAEQGASGSQDPGKPRVGKKAAEGQAAARRGSPAFLHSPSCPAIISSSEKLLAKKPPSEASELTFEGVPMTHSPTDPRPAKAEEGKNILAESQKEVGEKTPGQAGQAKMQGDTSRGIEFQAVPSEKSEVGQALCLTAREEDCFQILDDCPPPPAPFPHRMVELRTGNVSSEFSMNSKEALGGGKFGAVCTCMEKATGLKLAAKVIKKQTPKDKEMVLLEIEVMNQLNHRNLIQLYAAIETPHEIVLFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSMGVITYMLLSGLSPFLGDDDTETLNNVLSGNWYFDEETFEAVSDEAKDFVSNLIVKDQRARMNAAQCLAHPWLNNLAEKAKRCNRRLKSQILLKKYLMKRRWKKNFIAVSAANRFKKISSSGALMALGV
What is the function of this protein?
Implicated in the level of global muscle contraction and cardiac function.  Phosphorylates a specific serine in the N-terminus of a myosin light chain.
What are the official names of this protein?
Myosin light chain kinase 2, skeletal/cardiac muscle, MLCK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Protein: GLNB_CERSP
Sequence: MKKIEAIIKPFKLDEVKEALQAAGVQGLSVTEVKGFGRQKGHTELYRGAAYVVDFLPKVKIEVVLADDMVEAAVEAIVSASRTDKIGDGKIFISPVEQAIRIRTGETGEDAV
What is the function of this protein?
P-II indirectly controls the transcription of the glutamine synthetase gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.  When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme.
What are the official names of this protein?
Nitrogen regulatory protein P-II, PII signal transducing protein.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: NIKC_STAA8
Sequence: MHKIFSKNNLIFFVFVAFIFVVIVLQFFVSSENATKVNLSQTFEPISWLHLLGTDDYGRDLFTRIIIGARSTLFVTVLTLIAIVVIGVTLGLFAGYKKGWIERLVLRFIDVGLSIPEFIIMIALASFFQPSLWNLVISITLIKWMNYTRLTRSIVNSEMNKPYIKMAQLFHVPTRTILIRHLTPKIIPAIIVLMVVDFGKIILYISSLSFIGLGAQPPTPEWGAMLQQGRDFISSHPIMLIAPASVIAITILIFNLTGDALRDRLLKQRGEYDESH
What is the function of this protein?
Part of the ABC transporter complex NikABCDE (Opp2) involved in nickel import.  Probably responsible for the translocation of the substrate across the membrane.  Required for full urease activity and plays a significant role in the virulence of S. aureus during urinary tract infection (UTI).
What are the official names of this protein?
Nickel import system permease protein NikC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTND_LEPBJ
Sequence: MATIVRQKGLAPIEETSEVKSFLKERGIDYDHWKVPYNAADLTDKEILADVEKEELLKKLDDRFETLKEKEGYQSRDLIVLHPNVSGLNDMLAKFDRVHYHTDEEVRYIVDGSGVFGFVLKGEKFLVHVVKDDFISVPRNTNHWFYLDDKKRIKAVRYFRDMSGWVPNYVEETNSLD
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: BIOB_SYNP2
Sequence: MVQVPIKPTPQTPAPTTAIPNGPALEAWLNDWAQRIINGDRLTRTEALRLTAITGPENILKLCAAADLIRHECCGNTVDLCSIVNVKSGSCSENCSFCSQSAHHPGEDSPVYGLKTAEEIIEQAKAAEAAGAKRFCLVSQGRGIKYNSPRDTEFEQILETVRRIQAETAIKPCCALGEVTPEQAQQLREAGVTRYNHNLEASENFFPDIVTTHSWQDRVETIKNLKAAGIQACSGGIMGLGESWEDRVDLAIALRDLEVESVPLNLLNPRQGTPLGSNDRLDVYEALKCMAIFRFILPEQIIRYAGGREAVMGELQHLGLKAGINAMLIGHYLTTMGQPPEQDQAMLKSLGLQGGEAPIPGQYSAAQ
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: MIAA_KOCRD
Sequence: MSAPDAGREDTRIPLVAVVGPTGTGKSELAIALARELDGEVVNADALQLYRGMDVGTAKLTPEERQGVPHHLLDVLEIHEEASVAAFQRDARRAVDEIRGRGRVPVLVGGSGLYVRAALDAIEFPGTDATVRARREEQLRERGRAALLRELAAVDPGSAERVKDDRRLVRALEVHDLTGRPFTSFMPERRYVQPTVQIGLAMDREVLNRRLAHRVDLMLERGWLEEVKALEARGLRESPTAGRALGYPQLLAVLDGSATLDEAREDTVAATRRFTKRQRTWFGADPRVHWLDAGDPNGIDGLTAGAVRLVAAQ
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NRAM_I96A0
Sequence: MNPNQKIITIGSICMVVGIISLMLQIGNIISIWVSHSIQTGNQHQAEPCNQSIITYENNTWVNQTYVNISNTNFLTEKAVASVTLAGNSSLCPISGWAVHSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPHRTLMSCPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFKMEKGKVVKSVELNAPNYHYEECSCYPDAGEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGVFGDNPRPNDGTGSCGPVSPNGAYGVKGFSFKYGNGVWIGRTKSTNSRSGFEMIWDPNGWTGTDSSFSVKQDIVAITDWSGYSGSFVQHPELTGLDCIRPCFWVELIRGRPKESTIWTSGSSISFCGVNSDTVGWSWPDDAELPFTIDK
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: MSCL_ECOHS
Sequence: MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TMCAL_GEOTN
Sequence: MKAVGIIVEYNPFHNGHWHHLQETKAKTAADCLIAVMSGNFLQRGEPAIVSKWARTKMALAAGVDIVIELPYVFAVQAAEQFAHGAVRLLDALGCQELCFGSESGDIAAFLTAAKTWFQHKEKFDSLVRSELARGQSFPKANAEAWRQLDSDALDLSKPNNVLGFAYVKAIWQNKLAIVPRTIPRLAAGYHDESFSHSSIASATSLRKVLRQTGQLERIAAYIPSTTAEQLQQYRLTYGRWHDWEAYFPLLKYRLLTSSEEDLRRIAGVEEGIEYRLKQKIVSAETFATFIAATKTKRYTWTRLQRLCVHVLTNFTKEEQNKAAAPTYIRLLGMNETGRRYLQQVKKELALPLIAKAAKLNGDPLYEQEKRATAVYTAAFPEPLYSAALKEEYATAPIYFSGMERK
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS17_SOLHA
Sequence: MELCTQTVAADHEVIITRRSGSHHPTLWGDHFLAYADLRGANEGEEKQNEDLKEEVRKMLVMAPSNSLEKLELINTIQCLGLAYHFQSEIDESLSYMYTHYEEYSIGDLHAIALCFRLLRQQGYYVSCDAFKKFTNDQGNFKEELVKDVEGMLSLYEAAQFRVHGEQILDEALNFTITKLKQILPKLSNSQLAQQITNALKFPIKDGIVRVETRKYISFYQQNQNHNQVLLNFAKLDFNILQTLHKKELSDMTRWWKKMELVNTLPYARDRLVECYFWCLGTYFEPQYSVARKMLTKISFFISIIDDTYDIYGKLDELTLFTQAIERWNIDASEQLPLYMKIIYRDLLDVYDEIEKELANENKSFLVNYSINEMKKVVRGYFQEAKWYYGKKVPKMEQYMKNAISTSAYILLTTTSWLAMGNVATKDVFDWVATEPKLVVASCHIIRLLNDLVSHEEEQKRGNAASAVECYMNEYSVTQEEAHVKIRDIIENYWKDLNEEYFKVDMIIIPRVLLMCIINLTRVAEFIYKDEDAYTFSKNNLKDVISDILVDPII
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:21818683).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into gamma-gurjunene, (E)-beta-farnesene and (+)-valencene, and of (2Z,6Z)-farnesyl diphosphate ((ZZ)-FPP) into (E)-alpha-bergamotene and (Z)-gamma-bisabolene as well as beta-bisabolene, (Z)-alpha-bergamotene and (E)-gamma-bisabolene to a lower extent (PubMed:21818683).  Can act with a low efficiency as a monoterpene synthase with geranyl diphosphate (GPP) as substrate, thus producing beta-myrcene, (E)-beta-ocimene, limonene, terpinolene, gamma-terpinene and (Z)-beta-ocimene (PubMed:21818683).
What are the official names of this protein?
Terpene synthase 17, ShTPS17, (+)-valencene synthase TPS17, (E)-beta-farnesene synthase TPS17, (E)-beta-ocimene synthase TPS17, (E)-gamma-bisabolene synthase TPS17, (Z)-beta-ocimene synthase TPS17, (Z)-gamma-bisabolene synthase TPS17, Alpha-bergamotene synthase TPS17, Beta-bisabolene synthase TPS17, Beta-myrcene synthase TPS17, Gamma-gurjunene synthase TPS17, Gamma-terpinene synthase TPS17, Limonene synthase TPS17, Terpinolene synthase TPS17.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
Protein: CFT1_ASPOR
Sequence: MQCYTELLPPTGVTHSLALPFISESANNLVVARTSRLQIFSLLDVGPRPGGIEEQGVPKLVLEREYALPGTVTDLCRVKLLNTKSGGEAILLAFRNAKLALIEWDPGRYGICTISIHYYERDDSTSSPWVPDLSSCGSILSVDPSSRCAVFNFGIRNLAILPFHQPGDDLVMDDYGELDDERLGSHGLESGTDCDMTKESIAHRAPYSSSFVLPLAALDPSILHPISLAFLYEYREPTFGILYSQVATSNALLHERKDVVFYTVFTLDLEQRASTTLLSVSRLPSDLFKVVALPPPVGGALLIGSNELVHVDQAGKTNAVGVNEFSRQVSSFSMTDQSDLALRLEGCIVERLSETNGDLLLVPTTGEIVLVKFRLDGRSVSGISVHPIPPHAGGDIVKSAASSSAFLGDKRVFLGSEDADSILLGWSVPSSGTKKPRPQARHTEEDSGGFSDEDQSEDDVYEDDLYATVPEVVVDGRRPSAESFGSSLYNFREYDRLLNIGPLKDIAFGRSFTSLGGEENAGNDSGLELVASQGWDRSGGLAVMKRGLELQVLNSMRTDLASCVWTASVAHMEEAVSKTTTQAENRECHQYVVVSKATSAEREQSEVFRVEGQELRPFRAPEFNPNEDVTIDIGTLIGKNRVVQILRSEVRSYDGDLGLAQIYPVWDEDTSEERMAISSSLVDPYVAILRDDSTLLLLQADDSGDLDEVELNEQIANSKWTSCCLYFDKTGIFSSISATSDELAQNSMTLFLMTQDCRLFIYRLPDQKLLAIIEGVDCLPPVLSSEPPKRSTTREVLTEIVVADLGDSWSSFPYLIIRSRHDDLAVYRPFISITKSVGEPHADLNFLKETNLVLPRITSGVEDQSSTEEVIKSVPLRIVSNISGFSAIFRPGVSPGFIVRTSTSSPHFLGLKGGYAQSLSKFQTSECGEGFILLDSKVLCFILLCLTYCILSFHTGCHSYYPWTIQQIPIGEQVDHLAYSSSSGMYVIGTSHRTEFKLPEDDELHPEWRNEMTSFFPEVQRSSLKVVSPKTWTVIDSPAEHVMAVKNMSLEISENTHERKDMIVVGTAFARGEDIASRGCVYVFEVIKVVPDPKRPEMDRKLRLVGKEPVKGAVTALSEIGGQGFLIVAQGQKCIVRGLKEDGSLLPVAFMDVQCHVSVVKELKGTGMCIIADAVKGLWFAGYSEEPYKMSLFAKDLDYLEVLAADFLPDGNKLFILVADSDCNLHVLQYDPEDPKSSNGDRLLSRSKFHTGNFISTLTLLPRTSVSSEQMISDVDAMDVDIKIPRHQMLITSQNGSVGLVTCVSEESYRRLSALQSQLTNTIEHPCGLNPRAFRAVESDGTAGRGMLDGKLLFQWLDMSKQRKVEIASRVGANEWEIKADFEAISGEGLGYL
What is the function of this protein?
RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB.  Involved in poly(A) site recognition.  May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity).
What are the official names of this protein?
Protein cft1, Cleavage factor two protein 1.
What is the protein family that this protein belongs to?
Belongs to the CFT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PHAB_SHIZO
Sequence: MSRVALVTGGSRGIGAAISIALKAAGYKVAASYAGNDDAAKPFKAETGIAVYKWDVSSYEACVEGIAKVEADLGPIDVLVNNAGITKDAMFHKMTPDQWNAVINTNLTGLFNMTHPVWSGMRDRSFGRIVNISSINGQKGQMGQANYSAAKAGDLGFTKALAQEGAAKGITVNAICPGYIGTEMVRAIPEKVLNERIIPQIPVGRLGEPDEIARIVVFLASDEAGFITGSTISANGGQFFV
What are the official names of this protein?
Acetoacetyl-CoA reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSPL5_PTEAA
Sequence: MVDIALRSAVVAFMVVSLSAMFTSTQHSEVHIIGFSIPVSLRWNRSQPFEFLVVVELLICAYAFVQFVYQSVVLAKNAVPTRRCIWVQLAADQVCAYLVLAAAAAAAGASRTNKSGFQSLGMQNIKVPGVCIVLDKFCNRATIAIIFTLLAAGASGISVTLDVYMLTLTYYMG
What are the official names of this protein?
CASP-like protein 3A1, PaCASPL3A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TSAD_ECOSE
Sequence: MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAGZ_BACSU
Sequence: MRPVFPLILSAVLFLSCFFGARQTEASASKRAIDANQIVNRMSLDEKLGQMLMPDFRNWQKEGESSPQALTKMNDEVASLVKKYQFGGIILFAENVKTTKQTVQLTDDYQKASPKIPLMLSIDQEGGIVTRLGEGTNFPGNMALGAARSRINAYQTGSIIGKELSALGINTDFSPVVDINNNPDNPVIGVRSFSSNRELTSRLGLYTMKGLQRQDIASALKHFPGHGDTDVDSHYGLPLVSHGQERLREVELYPFQKAIDAGADMVMTAHVQFPAFDDTTYKSKLDGSDILVPATLSKKVMTGLLRQEMGFNGVIVTDALNMKAIADHFGQEEAVVMAVKAGVDIALMPASVTSLKEEQKFARVIQALKEAVKNGDIPEQQINNSVERIISLKIKRGMYPARNSDSTKEKIAKAKKIVGSKQHLKAEKKLAEKAVTVLKNEQHTLPFKPKKGSRILIVAPYEEQTASIEQTIHDLIKRKKIKPVSLSKMNFASQVFKTEHEKQVKEADYIITGSYVVKNDPVVNDGVIDDTISDSSKWATVFPRAVMKAALQHNKPFVLMSLRNPYDAANFEEAKALIAVYGFKGYANGRYLQPNIPAGVMAIFGQAKPKGTLPVDIPSVTKPGNTLYPLGYGLNIKTGRPL
What is the function of this protein?
Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.  Cleaves muropeptides, but not peptidoglycan.
What are the official names of this protein?
Beta-hexosaminidase, Beta-N-acetylhexosaminidase, N-acetyl-beta-glucosaminidase, N-acetylglucosaminidase, ORF1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Secreted, cell wall. Note=Detected in the culture supernatant, predominantly associated with cell wall-derived particulate material. A minor proportion is detected in the soluble fraction.
Protein: LEU1_PSEE4
Sequence: MTMLKDPSKKYRAFPTIDLPDRTWPSKTITQAPIWCSSDLRDGNQSLIEPMDSEKKLRFWKTLVQVGVKEIEASFPSASQTDFDFVRTLIEDGHIPDDTTIQVLTQAREDLIARTFESLRGAKKAIVHLYNATCPSFRRIVFNQDKQGVKDIAVNAAKLFVKYAAQQPDTHWTFQYSPETFSATELEFAKEVCDAVIEVWNPTPEHKIILNLPATVEVATPNVYADQIEWFCRNINRRDSVIISLHTHNDRGTGIAATELGLMAGADRAEGCLFGNGERTGNVDLVTLALNLYTQGIDPQLDFSDIDGVRKVVEECNQLPVHPRHPYVGDLVHTAFSGSHQDAIRKGFAKQQEGELWEVPYLPIDPADIGRSYEAVIRVNSQSGKGGITYLLEQEYGISLPRRMQIEFSQVVQGETDRLGLEMTAEQIYKLLQKEYLQANAPYALVSHRLQEENGSSHVQVEVSGEGETTLHWHGKGNGALEALVAGLPVNVEIMDYNEHAIGAGTNAKAAAYIELRVAGGRPVHGVGIDENITTASFKALFSALNRSLSQQQAKAA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.