PharMolix/UniProtQA huggingface dataset:
Protein: TFDP2_HUMAN
Sequence: MTAKNVGLTSTNAEVRGFIDQNLSPTKGNISFVAFPVSNTNSPTKILPKTLGPINVNVGPQMIISTPQRLTSSGSVLIGSPYTPAPAMVTQTHIAEATGWVPGDRKRARKFIDSDFSESKRSKKGDKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVSEFTNSNNHLAADSAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEIEKQRRIERIKQKRAQLQELLLQQIAFKNLVQRNRQNEQQNQGPPALNSTIQLPFIIINTSRKTVIDCSISSDKFEYLFNFDNTFEIHDDIEVLKRMGMSFGLESGKCSLEDLKLAKSLVPKALEGYITDISTGPSWLNQGLLLNSTQSVSNLDLTTGATLPQSSVNQGLCLDAEVALATGQFLAPNSHQSSSAASHCSESRGETPCSFNDEDEEDDEEDSSSPE
What is the function of this protein?
Can stimulate E2F-dependent transcription.  Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication.  The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase.  The E2F1:DP complex appears to mediate both cell proliferation and apoptosis.  Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812).
What are the official names of this protein?
Transcription factor Dp-2, E2F dimerization partner 2.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYSG_SALPA
Sequence: MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLEAGARLTVNALNFIPQFTVWANEGMLTLVEGPFDETLLDSCWLAIAATDDDTVNQRVSDAAESRRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPQHLGQVARYAGQLRARVKKQFATMGERRRFWEKFFVNDRLAQSLANADEKAVNATTERLFSEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQQADIVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCHAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQEKLIAFGMQADMPVALVENGTSVKQRVVHGVLTQLGELAQQVESPALIIVGRVVALRDKLNWFSNH
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: RUVA_LIMRJ
Sequence: MYEYLTGLVTVVAPQYIVVDVNGVGYKLLVANPYRYQEDRTKKVQVYVYQAVREDNISLFGFTDQNEKNLFMQLINVSGIGPKSALAILANPDHQGLVDAITNNNVSYLTKFPGIGKKTASQIVLDLRDKLTNESSSSLFATTQLTVDATVNRELKDALEALAALGYKERDIKKVQKALMKEEQMATDEYLRQALRLLN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: ARGB_CHLCH
Sequence: MSSERKAPHAAIGQVLIEALPYIRQFEGKTFVIKYGGAAMKDDTLKNMFAQNVTLLRKVGIRIVLVHGGGDAITRTAEKLGLQSRFVQGRRVTDKEMISVIQMTLAGKVNQDIVQLISEHGGKAVGVSGLDADTIKAHPHPNAEQLGLVGEVEQINTDYIDLLSQAGLIPVIAPVGFDCDGNLYNINADDAASSISIALKAEKLIYVSDVAGIQVGDKILKTISKAEAADLIERGIISGGMIPKVVSAFNTMDGGVGKVHLIDGKSTHSLLLEIFTHEGVGTQFIN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBL2_ARATH
Sequence: MGEIGFTEKQEALVKESWEILKQDIPKYSLHFFSQILEIAPAAKGLFSFLRDSDEVPHNNPKLKAHAVKVFKMTCETAIQLREEGKVVVADTTLQYLGSIHLKSGVIDPHFEVVKEALLRTLKEGLGEKYNEEVEGAWSQAYDHLALAIKTEMKQEES
What is the function of this protein?
May not function as an oxygen storage or transport protein, but might act as an oxygen sensor or play a role in electron transfer, possibly to a bound oxygen molecule.  Has a low affinity for O(2).
What are the official names of this protein?
Non-symbiotic hemoglobin 2, ARAth GLB2, Hb2.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: HIS3_CUPMC
Sequence: MAKKWLNKVKWDDNGLVPVIVQEVGSNDVLMFAFMNRDALQRTVELGEAVFWSRSRKRLWHKGEESGHVQKVHEIRLDCDEDVVLLKVTQIDSIACHTGRHSCFFQKFEGDVESGDWQTVEPVLKDPSSIYAAKP
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPB_WOLPM
Sequence: MDLNKFTEKAKSLIQSAQMKALGAGHQIFMPEHLLKVMLEDESGLVQDLINACGGNVQSISDAVDSAIKKLPVIEGPGSGGLQLSREIAKVFEDSIGIAKRNKDSFVAVERLLQGLTAQKDDTVGKILAENGVTPQKLNSVVAEMRKGSSADSPNSEEKLNAAKKYTKDVTELAMQGKLDPVIGRDEEIRRTMQVSLRRTKNNPVLIGEPGVGKTAIVEGLANRIVANDVPLGLHDAKVLALDLGALIAGTKFRGEFEERLKAVINELSRAEGKVILFIDELHTLVGAGATSGAMDASNLLKPALARGEVRCIGATTLDEYRQHIEKDPALARRFQPVFISQPTETDTISILRGLKERYEVHHGIRITDGAIIAAATLSNRYITDRFLPDKAIDLIDEAASRVRIEMDSKPEVIDELERKVIQLKIEAEALKKESDENSKQRLKKINEEIENLNSKFADLNSKWQMEKNKIARIQETAEKLDNARKELELVQRSGNLGRAGELMYGVIPQLENELKNQEKVTDSFLKKEVTGDDIANIVSKWTGIPVDNMMHSEKEKLLNMENEIGRRVIGQKDAIEAISNAVRRSRSGVQDTNKPFGSFLFLGPTGVGKTELAKALAEFLFDDQSALLRFDMSEYMEKHSVSKLIGAPPGYVGYEQGGRLTEAVRRRPYQVILFDEIEKANPDIFNLLLQILDEGRLTDSHGKLIDFRNTILILTSNLGAEIMLKGNVDSVRNEVMQIVKSAFRPEFLNRLDEIIIFHSLTRDDIYKIIDVQFSYLQKTLAKRKLSISLLQEAKELIAQTGYDPEYGARPLKRVIQECIQNNLAKLVLSGEVVENDELIVYALDNEILVKKV
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y196_VIBCM
Sequence: MERLIEKLLYSSRWIMAPIYLGLSLLLLALGIKFFQEIFHLLPNIFTIKEVDLILVALSLIDVSLVGGLIVMVMFSGYENFVSKLDVDESEDKLGWLGKLDTSSLKNKVSASIVAISSIHLLKVFMNTENIESDKIKWYLLLHITFVVSAFAMGYLDKITKK
What are the official names of this protein?
UPF0114 protein VCM66_0196.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPH_CERS4
Sequence: MTMPPLTLYLAAPRGFCAGVDRAIKIVEMALEKWGAPVYVRHEIVHNKFVVDRLRDMGAVFVEELDEAPTDRPVIFSAHGVPKAIPAEAERRNMVYVDATCPLVSKVHLEAERHHENGLQMIMIGHAGHPETVGTMGQLPEGEVLLVETVEDVAGLEVRDPERLAYITQTTLSIDDTAAIVAALRERFPAIAIPRKEDICYATTNRQGAVKAIAGRIDALLVIGAPNSSNSKRLVEVGRAAGCRVAQLVQRATDIDWEALQGATAVGVAAGASAPEVLVDEVIAAFRARFDTTVEAVETVKERVEFKVPRILREPAETP
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: RNPA_THISH
Sequence: MAVDQGFPRSVRLTRPEQYKQVFGDARKLSDAGFTLLVRDNDGDSARLGLAISKKCARRAVDRQRIKRLVRETFRQHRQHLAPVDVVVMCRPAVTGWDNARIRASLERFWARLSTPCANP
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: IF11_BURP6
Sequence: MAKEELIELDGIVDEVLPDSRYRVTLDNGVVVGAYASGQMRRHRIRILAGDRVTLELSVYDLTKGRINFRHKDERRSDAAPRASARRR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOP9_HUMAN
Sequence: MGQGPRSPHKVGRRFPAGGKRGRGAKGSGRPLPGRKRQPWPPPDGRSEPAPDSHPHLSPEALGYFRRALSALKEAPETGEERDLMVHNIMKEVETQALALSTNRTGSEMLQELLGFSPLKPLCRVWAALRSNLRTVACHRCGVHVLQSALLQLPRLLGSAAEEEEEEEEDGKDGPTETLEELVLGLAAEVCDDFLVYCGDTHGSFVVRTLLQVLGGTILESERARPRGSQSSEAQKTPAQECKPADFEVPETFLNRLQDLSSSFLKDIAVFITDKISSFCLQVALQVLHRKLPQFCAHLCNAVIGYLSTRGSSVDGSPLLLFLRDQTSSRLLEQVLLVLEPPRLQSLFEEHLQGQLQTLAAHPIANFPLQRLLDAVTTPELLSPVFEELSPVLEAVLAQGHPGVVIALVGACRRVGAYQAKVLQLLLEAFHCAEPSSRQVACVPLFATLMAYEVYYGLTEEEGAVPAEHQVAMAAARALGDVTVLGSLLLQHLLHFSTPGLVLRSLGALTGPQLLSLAQSPAGSHVLDAILTSPSVTRKLRRRVLQNLKGQYVALACSRHGSRVLDAIWSGAALRARKEIAAELGEQNQELIRDPFGHHVARNVALTTFLKRREAWEQQQGAVAKRRRALNSILED
What are the official names of this protein?
Nucleolar protein 9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
Protein: HSLV_CHLPM
Sequence: MKHSEESRIRSTTVIGVLRDGKAALGSDGQMTLGNTVVKHSTRKIRSLYQGRLLAGFAGATADALTLLDRFEEKLEAYNGKLERAAVELARDWRTDKYLRRLEAMLAIVSSEKALIISGTGDVIEPEDGIVAIGSGSMYALAAARALMKHTGLHAGEIVQESLRTAADICIYTNDHIVVEEV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROD_COXBU
Sequence: MLNTPRICVVVIGKTLEEFLSQLEAAQTAVDFVELRIDYLEQINPNWVRIIKNHTHKKAILCCRARADGGKFLGTPEAQQEILQAGNDLGFDYLDIDLPVANKISIHEKKAKIIISYHNFLHTPPITELNFLLENMRLFNPDVFKFATKSEQYEDVKTLFKLLINKKNNENMIVLGMGEQGKIIRLLSPLLGGYLTFSSINGAISAPGQIDFKTMQDFYQRFYKISSPLKGED
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: PDXJ_PHOPR
Sequence: MNNILLGVNIDHIATLRNARGTRYPDPVHAAEVAERAGADGITVHLREDRRHINDRDVRILKETIQTRMNLEMAVTDEMVSIALDTKPEFVCLVPEKREELTTEGGLDVAGQLEKIKAATQKLTDAGIKVSLFIDADRAQIDATLACGAPFVELHTGHYADAETEEAQQAELEKIASAATYAHGLGIKVNAGHGLTYHNVKPIAALPELYELNIGHSIISRAAFDGLNKAVADMKVEMLDARR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_CUTAK
Sequence: MTDTPTENLENTEVTPFTEGDREIAYRTDSNPTVAAGDSKRPAMIAPGAATGRRKEAIARVRIIPGSGQWKINGRTLEDYFPNKVHQQIVTEPFATAGVEGAYDVIARIGGGGVTGQAGALRLGIARALNNVDPEASRPALKKAGMLTRDARVKERKKAGLKKARKAPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RECO_SHIB3
Sequence: MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTYCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: RLMH_POLAQ
Sequence: MRLTIVSVGHKMPDWVATATHDYIKRMPADCSIEIKEIKPDLTPAKEAVKIAAAIPKGSRVIALDERGKDQTTQHLATQLAGWRQEGFDITFLIGGADGLDPSLKTNAQAMWRLSSLTLPHAMARVLLVEQLYRAWTILQGHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_SHEFN
Sequence: MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGHIGGNLWVVKCQVHAGGRGKAGGVKVTGNKDEIRAFAENWLGKNLVTYQTDAKGQPVAKILVESCTDIANELYLGAVVDRSTRRVVFMASTEGGVDIETVAEHTPELIHTAIIDPLTGPQAFQARDLGFKLGLNPTQMKQFTKIFMGLANMFNDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQPKIKAMHDPSQDDAREAHAAKFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAATSLTDAAEQVVKAAEGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PYRB_SYNR3
Sequence: MEVIARPPLSRWSYRHVLDLAAFSQEDYATVLELASRFRALPMSGPRRLPALQGRLVTTLFFEPSTRTRSSFELAARRLSADVQSFSPASSALAKGESLLDTARTYVAMGADVLVVRHRCAGVPAELARDLEAAGCRTAVLNAGDGLHSHPSQALLDLFTLARHFNPETPTLEALAGKRIVIVGDVLHSRVARSNLWSLTACGVDVVLCGPASLLPDAFAQFTHAPPPGQAQDLVAQRGSLRIERDLDRALEGADAVMTLRLQQERMKEQLITSLEAYHQRYGLSHRRLERCGKSVPVLHPGPVNRGVELSGELLDDPSRSLVEEQVRNGIPVRMALLYLMAASEPASSAAGLS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: PUR9_NEIG1
Sequence: MSVIKRALISLSDKAGAVEFAQNLHKLGVEILSTGGTAKLLAGAGVPVIEVADYTGFPEMLDGRVKTLHPKIHGGILGRRDLDEHVAKMEEHGIGNIDLVCVNLYPFAATIAKPGCTLEDAIENIDIGGPTMVRSAAKNWKHVAIVTDTADFPAIAAELEANNGALSDKTRFNLSRKAFSHTAQYDGMISNYLTSLSDGVLSGEPEIGEFPSRFNQSWIKVQDMRYGENPHQRAAFYRDIDPAAGSLSAYNQLQGKELSYNNIADADAAWEAVKSFDAPACVIVKHANPCGVAVAADTLTAYKLAYATDTTSAFGGIIAFNREVDGETVKQITDNQFMEVLMAPKFTAEALEIAAAKKNVRVLEVPLKAGANRFELKRVGGGLLVQTPDINRINRADLKVVSKRQPTEQEWNDLLFVWNVAKYVKSNAIVFGKGGQTYGIGAGQMSRVDSTRIAARKAQDAGLDLNGACAASDAFFPFRDGVDVIAEQGIKAIIHPAGSMRDQEVFDAADEHGIAMAVTGIRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: XERC_SHIDS
Sequence: MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDAAMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerC specifically exchanges the top DNA strands.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AG45_MYCLE
Sequence: MSVIAITVFIVTYALIASDRVNKTLAALTGAAIVVTLPIINSEDVFYSHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIWTAKRSHGSPLRILLLLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTINAAPFLMAEVFASNIGGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVIIVTVVLSALLPRLFRGAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLLLVFVAFIAHPVLHTGPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFFAGLFIMVGALVKTDVVNQLARATTTLTGGHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVSELVASMPDQSHTDILWWALALGADFGGNLTAVGASANVVMLEIAKSAGTPISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS
What are the official names of this protein?
46 kDa membrane protein.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SFGH1_ECO57
Sequence: MELIEKHASFGGWQNVYRHYSASLKCEMNVGVYLPPKAAGEKLPVLYWLSGLTCNEQNFITKSGVQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIRNELPDLVMNHFPATAKKSISGHSMGGLGALVLALRNPDEYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKEAWLDYHPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTQNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNMR
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase FrmB, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: H2BS2_STRPU
Sequence: MPRSPSKTSPRKGSPRRGSPSRKASPKRGGKGAKRAGKGGRRRNVVRRRRRRRESYGIYIYKVLKQVHPDTGISSRGMSVMNSFVNDIFGRIAGEASRLTRANRRSTISSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTTSR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.2, sperm.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PE2R4_PANTR
Sequence: MSTPGVNASASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAVTSVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI
What is the function of this protein?
Receptor for prostaglandin E2 (PGE2).  The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase.  Has a relaxing effect on smooth muscle.  May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function (By similarity).
What are the official names of this protein?
Prostaglandin E2 receptor EP4 subtype, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, Prostanoid EP4 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VNFG_AZOCH
Sequence: MSQSHLDDLFDYTEERCLWQFFSRTWDREENIEGVLGQVARLLTGQEPLRGTPQERLFYADALAMANDVRERFPWASQINHEEIHFLIDGLKSRLVDTVIQSSTNRELNHHLY
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.
What are the official names of this protein?
Nitrogenase vanadium-iron protein delta chain, Dinitrogenase 2 subunit delta, Nitrogenase component I.
Protein: EIF3M_HUMAN
Sequence: MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKLVKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGLLHEQNMAKMRLLTFMGMAVENKEISFDTMQQELQIGADDVEAFVIDAVRTKMVYCKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLNAWKQNLNKVKNSLLSLSDT
What is the function of this protein?
(Microbial infection) May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m, Fetal lung protein B5, hFL-B5, PCI domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
Protein: MURA_HELP2
Sequence: MDFLEIVGQVPLKGGVEISGAKNSALPILAATLLSQQEVKIKSLPQVVDIKAMALLLQNLGAELEWLDPNTLQIGAKSLHHTEATYDLVRKMRASILVLGPLLARFKECLVSLPGGCAIGARPVDLHLKAMQQLGAEIKIEQGYIHAKASKGLKGNDILFDKISVTGTENALMAASLAKGITRIINAAKEPEIAQLCTFLQSGGVEIEGVGSSELKIRGVENDALNLKDIQIIPDRIEAGTYLCVGAITNSQLKIHRIIPNHLQAITDKLIEIGFSLDIQENSIEIYPAKKRQAFEITTKEYPGFPTDMQAQFMALATQCLGTSVIEETLFENRFMHASELQRLGANISLKTNVATISGSTELTGSDVMATDLRASSALILAALVAKGVSRVHRIYHLDRGYERLEDKINALGAKVLRLKEK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.