PharMolix/UniProtQA huggingface dataset:
Protein: RS2_BURMA
Sequence: MAITMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYNDALKYVRQLAANRGTILFVGTKRQSRDTIAQEALRAGMPYVNARWLGGMLTNFKTLKVSIKRLKDMEAAVEAGELEKMSKKEALLFEREIAKLQKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGVPVIAVVDTNHSPEGVDYVIPGNDDSSKAVALYAQGVADAILEGRANAVNEVVQAVRGDDEYVEENA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MIAA_SULSY
Sequence: MIVIAGATATGKTELCIKLAKLLDGEVISADSMMVYKYMDIGTAKPSVEEREGIEHYVIDVVLPSQNYSVKDYIEDFDKAVQKIREKGKIPIVVGGTWLYIQGALYGLSDAPESDWTLREKLYSLVNLELYTQLQKVDPEYANKIHVNDKRRIVRALEVYYLTGKPFSFFINQHNFKSKRYNFLGFILERDRQELMDRIEIRVEKMFEKGLVEEVKKLVDMGFKDSLTSMQAIGYKEILPYLDKKISLEDAKKCIIENTKDFAKRQIRTFRNKTDFEKIEASKFEVNEMLDYIYRKYNQEVRDVSTR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NXF2_HUMAN
Sequence: MCSTLKKCGTYRTEVAECHDHGSTFQGRKKGGSSFRDNFDKRSCHYEHGGYERPPSHCQENDGSVEMRDVHKDQQLRHTPYSIRCERRMKWHSEDEIRITTWRNRKPPERKMSQNTQDGYTRNWFKVTIPYGIKYDKAWLMNSIQSHCSDRFTPVDFHYVRNRACFFVQDASAASALKDVSYKIYDDENQKICIFVNHSTAPYSVKNKLKPGQMEMLKLTMNKRYNVSQQALDLQNLRFDPDLMGRDIDIILNRRNCMAATLKIIERNFPELLSLNLCNNKLYQLDGLSDITEKAPKVKTLNLSKNKLESAWELGKVKGLKLEELWLEGNPLCSTFSDQSAYVSAIRDCFPKLLRLDGRELSAPVIVDIDSSETMKPCKENFTGSETLKHLVLQFLQQYYSIYDSGDRQGLLGAYHDEACFSLAIPFDPKDSAPSSLCKYFEDSRNMKTLKDPYLKGELLRRTKRDIVDSLSALPKTQHDLSSILVDVWCQTERMLCFSVNGVFKEVEGQSQGSVLAFTRTFIATPGSSSSLCIVNDELFVRDASPQETQSAFSIPVSTLSSSSEPSLSQEQQEMVQAFSAQSGMKLEWSQKCLQDNEWNYTRAGQAFTMLQTEGKIPAEAFKQIS
What is the function of this protein?
Involved in the export of mRNA from the nucleus to the cytoplasm.
What are the official names of this protein?
Nuclear RNA export factor 2, Cancer/testis antigen 39, CT39, TAP-like protein 2, TAPL-2.
What is the protein family that this protein belongs to?
Belongs to the NXF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Cytoplasm. Note=Localized in the nucleoplasm and at the nuclear envelope. Shuttles between the nucleus and the cytoplasm.
Protein: TAL_BACTN
Sequence: MKFFIDTANLEQIQEAYDLGVLDGVTTNPSLMAKEGIKGTENQREHYIKICKIVNADVSAEVIATDYEGMIREGEELAALNPHIVVKVPCIADGIKAIKYFTEKGIRTNCTLVFSVGQALLAAKAGATYVSPFVGRLDDICEDGVGLVGDIVRMYRTYDYKTQVLAASIRNTKHIIECVEVGADVATCPLSAIKGLLNHPLTDSGLKKFLEDYKKVNG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1726_THEGJ
Sequence: MIRYPAVAGSFYPADDELILMLEKFFSDLGEEGSERRITAGVAPHAGYIFSGYTASRTYKAIFEDGLPETFVILGPNHTGLGSPIAVYPEGEWLTPLGSIEVDAEMAKEIAKLSGIADLDELAHKYEHSIEVQVPFIQYLTELAGKEVKIVPITLGIQDEDVSRALGKAIFEASEKLGRDVVVIASTDFMHYGPAYGYVPFRARADELPHRIKEWDFRLIRRILDFDVDGLFRELREMRHTMCGPGAVGTAIVYSRLAGAVEAELLHYTTSYEISRSTEAVVGYASIVMRR
What are the official names of this protein?
MEMO1 family protein TGAM_1726.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: PKHA2_BOVIN
Sequence: MPYVDRQNRICGFLDIEENENSGKFLRRYFILDTQANCLLWYMDNPQNLAIGAGAVGSLQLTYISKVSIATPKQKPKTPFCFVINALSQRYFLQANDQKDLKDWVEALNQASKITVPKAGNLPLTTEVLKSLATPLALEKKPQVAYKTEIIGGVVVHTPINQNGGDGQEVGEPGSHAILRRSQSYIPTTGCRGPTGPPLIKSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDREPLRTIFLKDVLKTHECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAVQALKCHPREMSFSRSISLTRPGSSSLSGGPNSILCRGRAPGEERKTLCKAPSLASSWQPWTPVPQAGEKLLPTEETAEDSLFTPRLGESSTSAVLPSSRIRHRSEPQHPKEKPFVFNLDDENIRTSDV
What is the function of this protein?
Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides.  May recruit other proteins to the plasma membrane (By similarity).
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 2, PH domain-containing family A member 2.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Note=Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2.
Protein: EFTS_CHLCV
Sequence: MSNFSMETLKLLRQQTGVGLTKCKEALAECNGNLEEAVVHLRKLGLASASKKEHRETKEGVIAAKSDARGTAVVEVNVETDFVANNAVFRTFVDGLVEDVLNHKVNSVDALLPLTSSQDASLTIDELRAVTMQTVGENIRISRIKYLPKTTEESVGIYSHGNGKAVSVTVLSGVADKESLAKDISMHIVAAQPLFLNKESVPADALEREKEVISSQVQGKPQAVIDKIISGKLGTFFQDVCLLEQAFIKNPDITIQGLVDDASKTSGNSVEVKEFILWKIGA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDHA_CHICK
Sequence: MSLKDHLIHNVHKEEHAHAHNKISVVGVGAVGMACAISILMKDLADELTLVDVVEDKLKGEMLDLQHGSLFLKTPKIISGKDYSVTAHSKLVIVTAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPDCKLLIVSNPVDILTYVAWKISGFPKHRVIGSGCNLDSARFRHLMGERLGIHPLSCHGWIVGEHGDSSVPVWSGVNVAGVSLKALHPDMGTDADKEHWKEVHKQVVDSAYEVIKLKGYTSWAIGLSVADLAETIMKNLRRVHPISTAVKGMHGIKDDVFLSVPCVLGSSGITDVVKMILKPDEEEKIKKSADTLWGIQKELQF
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase A chain, LDH-A.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CECE_BOMMO
Sequence: MNFTRIIFFLFVVVFATASGKPWNIFKEIERAVARTRDAVISAGPAVRTVAAATSVASG
What is the function of this protein?
Has antibacterial activity against Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Antibacterial peptide enbocin, Moricin.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LAT1_MOUSE
Sequence: MAVAGAKRRAVATPAAAAAEEERQAREKMLEARRGDGADPEGEGVTLQRNITLLNGVAIIVGTIIGSGIFVTPTGVLKEAGSPGLSLVVWAVCGVFSIVGALCYAELGTTISKSGGDYAYMLEVYGSLPAFLKLWIELLIIRPSSQYIVALVFATYLLKPVFPTCPVPEEAAKLVACLCVLLLTAVNCYSVKAATRVQDAFAAAKLLALALIILLGFIQMGKDMGQGDASNLQQKLSFEGTNLDVGNIVLALYSGLFAYGGWNYLNFVTEEMINPYRNLPLAIIISLPIVTLVYVLTNLAYFTTLSTNQMLTSEAVAVDFGNYHLGVMSWIIPVFVGLSCFGSVNGSLFTSSRLFFVGSREGHLPSVLSMIHPQLLTPVPSLVFTCIMTLMYAFSRDIFSIINFFSFFNWLCVALAIIGMMWLRFKKPELERPIKVNLALPVFFILACLFLIAVSFWKTPMECGIGFAIILSGLPVYFFGVWWKNKPKWILQAIFSVTVLCQKLMQVVPQET
What is the function of this protein?
The heterodimer with SLC3A2 functions as sodium-independent, high-affinity transporter that mediates uptake of large neutral amino acids such as phenylalanine, tyrosine, histidine, met hionine, tryptophan, valine, isoleucine and alanine (By similarity).  The heterodimer with SLC3A2 mediates the uptake of L-DOPA and leucine (PubMed:9915839, PubMed:11011012).  Functions as an amino acid exchanger (By similarity).  May play a role in the transport of L-DOPA across the blood-brain barrier (PubMed:11011012).  May act as the major transporter of tyrosine in fibroblasts (By similarity).  May mediate blood-to-retina L-leucine transport across the inner blood-retinal barrier (By similarity).  Can mediate the transport of thyroid hormones diiodothyronine (T2), triiodothyronine (T3) and thyroxine (T4) across the cell membrane.  When associated with LAPTM4B, the heterodimer formed by SLC3A2 and SLC7A5 is recruited to lysosomes to promote leucine uptake into these organelles, and thereby mediates mTORC1 activation.  Involved in the uptake of toxic methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes.  Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the membrane (By similarity).
What are the official names of this protein?
Large neutral amino acids transporter small subunit 1, 4F2 light chain, 4F2 LC, 4F2LC, L-type amino acid transporter 1, LAT1, Solute carrier family 7 member 5.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Located to the plasma membrane by SLC3A2/4F2hc (PubMed:9915839). Localized to the apical membrane of placental syncytiotrophoblastic cells. Recruited to lysosomes by LAPTM4B (By similarity). Expressed in both luminal and abluminal membranes of brain capillary endothelial cells (By similarity).
Protein: NK3R_MOUSE
Sequence: MASVPTGENWTDGTAGVGSHTGNLSAALGITEWLALQAGNFSSALGLPVTSQAPSQVRANLTNQFVQPSWRIALWSLAYGLVVAVAVFGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASVAAFNTLVNFIYGVHSEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSKIKVMPGRTLCYVQWPEGPKQHFTYHIIVIILVYCFPLLIMGVTYTIVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVVTFAICWLPYHVYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIQVSSYDELELKTTRFHPTRQSSLYTVSRMESVTVLYDPSEGDPAKSSRKKRAVPRDPSANGCSHREFKSASTTSSFISSPYTSVDEYS
What is the function of this protein?
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B).  It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Neuromedin-K receptor, NKR, NK-3 receptor, NK-3R, Neurokinin B receptor, Tachykinin receptor 3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB_PARD8
Sequence: MEDDFDIRDARMPENEREYENVLRPLSLRDFSGQAKVVENLKVFVMAARMRKEALDHVLLHGPPGLGKTTLSNIIANELGVGFKVTSGPVLDKPGDLAGVLTSLEKNDVLFIDEIHRLSPIVEEYLYSAMEDYRIDIVIDKGPSARSIQIDLAPFTLIGATTRSGLLTSPLRARFGINMHLEYYDMETLTKIVLRSANILNVKCELNAAREIASRSRGTPRIANALLRRVRDFAQVKGNGDIDKAIACFSLEALNIDRYGLDQIDNKLLTTIIDKFKGGPVGLTTIATALGEDPGTLEEVYEPFLIKEGFIKRTPRGREVTDLAYTHLGRSRVGEQGFLFD
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: SYKC_NOSCE
Sequence: MSTKNNSNVPEISDEEFYKNRLLTVTEQLKDNVQVYPHKYEVNYRFKDIFTFKDASEEDLKKVKVQSAGRILNFRIHARYSFFQVMSEDFTIQLVVDAQVLENKDIISNIKRGDIVGFSGVLGRTKTKEFSVFIKELSILTPCLRTIPTDYYGLKDPEIIYRKRYLDLLINKESKNRFIQRTNIIKFIRKYLDDKDFVEVETPLLNIIPTGAAAKPFTTHHNELKMNLFLRIAPELYLKKLVIGGMDRVYEIGKLFRNEGIDLTHNPEFTACEFYMAYADYNDMMNMAEEMLNGMCKYLHGSEKIVYAPNKREKEVKPVEINFARPFARFHMLEELSKVVGIKLDGLNINSDETLDLLIETCDKYEIKVEQPKTLTRVLDKLVGHFIEPKCINPSFIIGYPLVTSPLAKNHRSEAGMVERFELFINGKEICNAYTELNNPIEQRMRFKMQAQDINDGDDEAMITDEDFCVALEYGLPPTGGFGMGIDRLTMFMTDAANIKDVILFPAMKPESDN
What are the official names of this protein?
Probable lysine--tRNA ligase, cytoplasmic, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_CYAP4
Sequence: MSKGTLFDKVWDLHTVATLPSGQTQLFIGLHLIHEVTSPQAFAMLKERGLKVLFPERTIATVDHIVPTDNQARPFADSLAEEMMQALETNCQEHGIRFYNIGSGSQGIVHVIAPELGLTQPGMTIACGDSHTSTHGAFGAIAFGIGTSQVRDVLASQTLSLSKLKVRKIEVNGSLQPGVYAKDVILHIIRTLGVKAGVGYAYEYAGTTFEQMSMEERMTVCNMAIEGGARCGYVNPDAVTFAYLKEREFAPQTDWDTAQQWWQSIASDPDAVYDDVVVFDAADIAPTVTWGITPGQGIAVDQPLPLPEQLPASEQAIAEEAYQYMDLIPGQKLLGTKIDVCFIGSCTNGRISDLRAAAEIAQGRRVVPGLKAFVVPGSERVKQQAEAEGLDQIFQAAGFEWREPGCSMCLAMNPDKLQGRQISASSSNRNFKGRQGSATGRTLLMSPAMVAAAAVTGEVTDVRELLGQ
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: KBX31_OPICA
Sequence: MNNKLTALIFLGLLAIASCKWFNEKSIQNKIDEKIGKNFLGGMAKAVVHKLAKNEFMCVANVDMTKSCDTHCQKASGEKGYCHGTKCKCGVPLSY
What is the function of this protein?
The short synthetic peptide (20-54) has antimicrobial activity against the yeasts F. culmorum (IC(50)=8. 8 uM) and F. oxysporum (IC(50)=10 uM) P. aeruginosa, and the Gram-negative bacteria E. coli.
What are the official names of this protein?
Opiscorpine-1.
What is the protein family that this protein belongs to?
Belongs to the long chain scorpion toxin family. Class 3 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: STLSS_EMEVA
Sequence: MEYKFSTVVDPGTYETHGLCEGYEVRYHKNAELEDIGCLRCQEHWRQSVGPLGAFKGTLGNPFNLLSLVIPECLPDRLSIVGFANELAFIHDDVTDIVQYGDAHNNDFKEAFNSMATTGSMENAASGKRALQAYIAREMVRIDKERAIPTIKAWAKFVDYGGRQETTRFTSEKEYTEYRIQDIGLWFWYGLLSFAMALDVPEHEREMCHEVCRTAYVQIMLVHDLASWEKEKLNAAALGKDVITNIIFVLMEEHGISEEEAKERCRETAKTLAADYLKIVEEYKARDDISLDSRKYIESWLYTISGNTVWSFICPRYNSSGSFSDHQLELMKNGVPKDPASGSTNGTSNGTSNGTSHVAVNGNGHVTNDDLSANGIKTDGELLSAITMEHLKNRNSFKLGDHDQEVKSLHGHGQALDPRVLQAPYEYITALPSKGLREQAIDALNVWFRVPTAKLEIIKSITTILHNASLMLDDVEDGSELRRGKPATHNIFGLGQTINSANYQLVRALQELQKLGDARSLLVFTEELHNLYVGQSMDLYWTSNLVCPSMHEYFQMIEHKTGGLFRLFGRLMAVHSTNPVQVDLTDFTNHLGRYFQTRDDYQNLVSAEYTKQKGFCEDFEEGKFSLPMIHLMQTMPDNLVLRNVWTQRRVNGTATHGQKQTILNLMKEAGTLKFTQDSLGVLYSDVEKSVAELESKFGIENFQLRLIMELLKTG
What is the function of this protein?
Multifunctional diterpene synthase; part of the gene cluster that mediates the biosynthesis of the sesterterpene stellatic acid (PubMed:26351860).  The first step in the pathway is performed by the stellatatriene synthase that possesses both prenyl transferase and terpene cyclase activity, converting isopentenyl diphosphate and dimethylallyl diphosphate into geranylgeranyl diphosphate (GGDP) and then converting GGDP into stellata-2,6,19-triene (PubMed:26351860).  The cytochrome P450 monooxygenase Stl-P450 then catalyzes three successive oxidation reactions on the C-20 methyl group to generate the carboxylic acid of stellatic acid (PubMed:26351860).
What are the official names of this protein?
Stellatatriene synthase, SS, Stellatic acid biosynthetis gene clusters protein Stl-SS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FPP/GGPP synthase family.
Protein: NDHK_PROMM
Sequence: MSVTPSIDAVRDLRAASCGPVGAPSVTSDLSENIILTSLDDLHNWARLSSLWPLLYGTACCFIEFAALIGSRFDFDRFGLVPRSSPRQADLLIVAGTVTMKMAPALVRLYEQMPEPKYVIAMGACTITGGMFSADSTTAVRGVDKLIPVDLYLPGCPPRPEAIFDAVIKLRKKVGDESVAERIKIAQTHRYFTVPHHMKRVEPIVTGAYLSADTQKAALKPGAGLPMAAELNTPEIDVSPASQSSSTYES
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, NAD(P)H dehydrogenase I subunit K, NDH-1 subunit K, NDH-K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: THIG_THET2
Sequence: MDTWKVGPVELKSRLILGSGKYKDFGVMREAIAAAKAEVVTVSIRRVELKAPGHVGLLEALEGVRLLPNTAGARTAEEAVRLARLGRLLTGERWVKLEVIPDPTYLLPDPLETLKAAERLIEEDFLVLPYMGPDLVLAKRLAALGTATVMPLAAPIGSGWGVRTRALLELFAREKASLPPVVVDAGLGLPSHAAEVMELGLDAVLVNTAIAEAQDPPAMAEAFRLAVEAGRKAYLAGPMRPREAASPSSPVEGVPFTPTGPRPGRGPQ
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI61_HUMAN
Sequence: MEFVTALADLRAEASCPICLDYLKDPVTISCGHNFCLSCIIMSWKDLHDSFPCPFCHFCCPERKFISNPQLGSLTEIAKQLQIRSKKRKRQEEKHVCKKHNQVLTFFCQKDLELLCPRCSLSTDHQHHCVWPIKKAASYHRKKLEEYNAPWKERVELIEKVITMQTRKSLELKKKMESPSVTRLECSCTISAHFNLRLPGSSDSSASGS
What are the official names of this protein?
Putative tripartite motif-containing protein 61, RING finger protein 35.
Protein: YHZ9_SCHPO
Sequence: MVFKAHHRSITRQDIELEDLENAPASIASIENDTLEANVGSTPLTAKQKRNIYFLILLYLIQGVPMGLVRGSIPYFLKPNVSYSDLATYSLAAYPYSLKVLWSPIVDTYYCRSFGRRKTWVVPCMLLISSTLLLFSYNVDTWISKGSSYINSFTTWSFLLVFVCATQDIAVDGWSLNMLNPEQLSYASTAQTVGLNTGFFLSFTILLVFTSPEFANTFIRSIPSNEGLITLSGYIKFWAYFTFIASVLVCFWDESNHQEIANISDMWKTIRAALSLKNMRQLLIVHTLGKVGFVANETLTLLKATEFGLSNEMLSLIILINFPLGLALGVYTGRISNYRPLDIWLKGYWGRVVSILLNTILVYMVSNWKHRFPVFFPIFLCYTLNASFSTIQFVALGVFHSKISDPHIGGTYMTILNTLSNLGGSWPQYVMLRMADLLTVSSCSTAPHLTCSADAQKKECQALGGTCLYKRDGYYLTSIVGIFLAISICVSLITPVVRRLTKAPISSWHIHSKIAETYT
What are the official names of this protein?
Uncharacterized protein C21B10.09.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: INSD2_ECOLI
Sequence: MDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACNGLSDNRCLEI
What is the function of this protein?
Involved in the transposition of the insertion sequence IS2.
What are the official names of this protein?
Transposase InsD for insertion element IS2D.
Protein: AROC_STRT2
Sequence: MRYLTAGESHGPRLTAIIEGVPAGLPLTAEDINGDLKRRQGGYGRGGRMKIESDKVEITSGVRHGKTTGAPITLHVINKDHQKWLDIMAVEDIEDRLKTKRKITHPRPGHADLVGGMKYRFDDLRNSLERSSARETTMRVAVGAVAKRILAELDIEIANHVVVFGGKEIDVPENLTVAQIKELAQQSEISVVNQEREQEIKDYIDQIKKEGDTIGGVVETVVGGVPVGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGLGFKDGYLRGSQVMDEILWNEEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKATVERSDPTALPAAGVVMESVVATVVANEILDKFSSDNLEELKEAVAHHRDYVKNF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: NRDR_XYLFT
Sequence: MYCLFCQHTDTRVIDSRVSEDGATIRRRRECEACGERFSTLETIELKLPVIIKKDGGREAFDGRKLRTSFDRALQKRPVAEERIEMAMRAVIHRLRMAGEREVPSIVVGECVMAELRKLDHVGYVRFASVYRSFQDVADFREEIEKLESELLVSREQLPLLEAVMESIGHPSIDQGG
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PNCB_ESCF3
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYHDVHVAAEFRCRGDDLLGIYADAIREQVHAMQHLRLQEEEFQWLTGLPFFKPDYLNWLRDFRYNPEQVSVTNDNGKLNIRLTGPWLEVIMWEVPLLAVISELVHHYRSPEASVQLAMNTLEQKLADFTTLTAGLDMSRFHLMDFGTRRRFSRDVQEAIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLATSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYLKLGIDPQSKVLVFSDNLDLTKAIELYRHFSSRIKLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPQIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: BET3_SCHPO
Sequence: MSKSKIGEDVYKKVDKVNAELFVLTYGSIVAQLCKDMNYEKVNEELDKMGYNIGIRLIEDFLAKTEWPRCADFRETGETVAKVGFKVFLNFSPIISSVSDDGNTFVLTLDDNPLAEFVELPADARQKLWYSNILCGVIRGALEMLQMDVDAVFLRDILRGDEHTEIRVHLKRILKEEIPPGDE
What are the official names of this protein?
Transport protein particle subunit bet3, TRAPP subunit bet3.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: DRE2_NEOFI
Sequence: MAKQTLLLSPPSLSSQPGKLNETLQSYNRNATDLQMLDRLALGLASLPDSTYSTIVILAGGDNSFSESLKLINRQTFNQIIGSLRRGGYIYGQDAVSGVAFDHNEAILAGLIHVGNGKYLKPDIEEMQAVPLRLGRKNDHLAGAPSLEGSAAEHPFPPEVSEGKTASGDNRVAVVGSQKFRENIVSAATMDNNEASDDELINEDNLLDDSELSAPIIQPPECRPKAGKRRRACKDCTCGLAQKLQEEDAVKRADADEQLDAMKLLHDDLAEVDFTVRGKVGSCGNCSLGDAFRCEGCPFIGLPAFQPGEEVRLLNNDVQL
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins.  Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex cfd1-nbp35.  Electrons are transferred to dre2 from NADPH via the FAD- and FMN-containing protein tah18.  Tah18-dre2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit rnr2.
What are the official names of this protein?
Fe-S cluster assembly protein dre2, Anamorsin homolog.
What is the protein family that this protein belongs to?
Belongs to the anamorsin family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion intermembrane space.