PharMolix/UniProtQA huggingface dataset:
Protein: RL31_CLOK5
Sequence: MKKGIHPEYYHDSVVKCACGNTFTTGSTQKELKVEICSKCHPFFTGKQKLVDAGGRVDRFLKKFNLKNEE
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RL22_ANOFW
Sequence: MQAKAVARTVRIAPRKARLVIDLIRGKQVSEAVAILRHTPKAASPIIEKVLKSAVANAEHNYDMDVNKLVVTEAYVNEGPTLKRFRPRAQGRASAINKRTSHITIVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: HFLD_PSEU2
Sequence: MSPTQEQLIALGGVFQAAVLVDRIAKTGQISEAALSCMLGSLLVVDPKDTLDVYGGDDLNLHEGYRAMASALERDPATLQREPLRYALSMLGLERQLAKRDDLLEVIGKRIPVIQSQVEHFGIAHENVIAATGALYQDTLSTLRQRIQVQGDMRNLQQPNNASKIRGILLAGIRSARLWRQVGGHRWQLVFSRRKLLKELYPLLHG
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: HXA6_CHICK
Sequence: MSSYFVNPTFPGSLPAGQDSFLGQIPLYPAGYDALRHFPTSYGASSLQDKTYTSPCFYQQSNTVIACNRASYEYGASCFYSDKEISSASPSGSGKQRGQGDYLHFSPEQQYKSNGVQSKIVNDEGTDRKYTSPVYPWMQRMNSCAGTVYGAHGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKFINSTQPGSDETEEKSGE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A6.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YL178_MIMIV
Sequence: MGDFVFCYGLHNKNRLSKYIKQTKKGYKLYLDDDNHIKIKIETRSGQKYIVIDFNDSLDFLKFIVKKKIYCDEYKHDCNSLCLHNDYLEYVIENKHYDIVKFYCKKFVPLIKSNISVYPFSFSLFVDIDLDDFKYMFKYSCLEDINPYFIYVLGQSDNITIEFMDDIIGMYKSKLTRLFTNNKISDSNIDNIKIGLQDFIKPVYKKDDVNLFDFIIEEIHNLTSEIDKTKLYKKQLGFLKIFEFYYELDTKTINRFINYVLDCTCQKIFERLLFNLGNIDLLDKTIVRDILEFNMVEYMGIICDFIGDTNPELINKMLTKATSTEMAQLLIDCGADYEKLYKSQNFRKCNDCVKNFIKKLVKETSDS
What are the official names of this protein?
Uncharacterized protein L178.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L17x/L18x family.
Protein: GAL7_NEUCR
Sequence: MTDKVLDDISHRRYNPLNGSWLLVSPHRTKRPWQGQQEAPALNKLPEYDPQCYLCPGNKRAQGDSNPHYKNTFAFVNDYSAVKEEQQEYHPRKDAAGDGDDDIASLLLQAQPATGRCYVLTFSAKHDTTLADMSATEIVPVIETWTRIYASHLSASHPLRDAAARSLSEIPPNPDGEVEPAKKQQLRYMQIFENKGAAMGCSNPHPHCQIWTTSTLPEEPGKELAQMTKYHREHKGRHLLEDYVKVEMAKGERVVWQNDGFLVVCPWWAVWPFEVLVIAKRHVRALVELTSEERLQFAEAVQEVTRRYDNLFETNFPYSSGIHQAPLDCTEEEAETSWFHMHFYPPLLRSATVRKFLVGYELMAEPQRDITPEQAAARLRDCGGELYRKSLQ
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: RPOA_RHOP2
Sequence: MTIQKNWQELIRPNKLQVTAGSDATRFATLVAEPLERGFGQTLGNALRRVLLSSLQGAAVQSVHIDGVLHEFSSIAGVREDVTDIVLNIKDISLKMQGEGPKRMVVKKQGPGVVTAGDIQTVGDIVVLNPDLQICTLDEGAEIRMEFTVNTGKGYVAAERNRPEDAPIGLIPVDSLYSPVRKVSYKVENTREGQILDYDKLTMTVETNGALTPDDAVAFAARILQDQLNVFVNFEEPRKEVTQEIIPDLAFNPAFLKKVDELELSVRSANCLKNDNIVYIGDLVQKSEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEVPGWPPENIDELAKRFEDHY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RIMP_HAEIN
Sequence: MATLEQNLQEMLQDAVEDLGCELWGIECQRVGRFMTVRLFIDKDGGVTVDDCADVSRQVSAILDVEDPIADKYNLEVSSPGLDRPLFTLPQFERYIGQDIAVHLRIPVMERRKWQGKLERIEKDMITLIVDDQEQILVFGNIQKANVVAKF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_AQUAE
Sequence: MGEKVYIFDTTLRDGEQAPGFSMTTEEKLQMAHQLAKLNVDIIEAGFAAASKGDFEAVNRIAKEVKGPVICSLARALESDIEIAAKALEPAERKRIHTFIATSPIHMEYKLRMTPDQVLERIKKAVSFARNFTDDVEFSCEDATRSEREFLYRAIETAIKHGATVINIPDTVGYAIPEEFGQLIEDIMNNVPNIDKVILSVHCHDDLGLATANSLTAVKHGARQVECTINGIGERAGNAALEEVVMALKVRKDFFGDLYTDVNTKEIYKTSRLLCRITGNFVQPNKAIVGDNAFAHESGIHQHGVLSHRMTYEIMNPEDVGFPMSRIVLGKHSGRHALKRRLEELGFKFTKEELDRIFEKFKELADRKKEVYDEDLEALIYQEFMKIEDHEPVKVLHFQVQSGDNMIPTATVKLEFKGEEREASSTGNGPVDATIKAIQKALGIEPKLLDYSIKALTPNTDAQAEARVVLELDGVKASGRGVDTDIIKASVKAFTDALNRAIVRKEYIIQRQEIREEGTV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: SC5A1_RABIT
Sequence: MDSSTLSPLTTSTAAPLESYERIRNAADISVIVIYFLVVMAVGLWAMFSTNRGTVGGFFLAGRSMVWWPIGASLFASNIGSGHFVGLAGTGAASGIATGGFEWNALIMVVVLGWVFVPIYIRAGVVTMPEYLQKRFGGKRIQIYLSILSLLLYIFTKISADIFSGAIFIQLTLGLDIYVAIIILLVITGLYTITGGLAAVIYTDTLQTAIMMVGSVILTGFAFHEVGGYEAFTEKYMRAIPSQISYGNTSIPQKCYTPREDAFHIFRDAITGDIPWPGLVFGMSILTLWYWCTDQVIVQRCLSAKNLSHVKAGCILCGYLKVMPMFLIVMMGMVSRILYTDKVACVVPSECERYCGTRVGCTNIAFPTLVVELMPNGLRGLMLSVMMASLMSSLTSIFNSASTLFTMDIYTKIRKKASEKELMIAGRLFMLFLIGISIAWVPIVQSAQSGQLFDYIQSITSYLGPPIAAVFLLAIFWKRVNEPGAFWGLVLGFLIGISRMITEFAYGTGSCMEPSNCPTIICGVHYLYFAIILFVISIITVVVVSLFTKPIPDVHLYRLCWSLRNSKEERIDLDAGEEDIQEAPEEATDTEVPKKKKGFFRRAYDLFCGLDQDKGPKMTKEEEAAMKLKLTDTSEHPLWRTVVNINGVILLAVAVFCYAYFA
What is the function of this protein?
Electrogenic Na(+)-coupled sugar simporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1.  Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump (By similarity).  Has a primary role in the transport of dietary monosaccharides from enterocytes to blood.  Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2.  Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis (By similarity).  Together with SGLT2, functions in reabsorption of D-glucose from glomerular filtrate, playing a nonredundant role in the S3 segment of the proximal tubules (By similarity).  Transports D-glucose into endometrial epithelial cells, controlling glycogen synthesis and nutritional support for the embryo as well as the decidual transformation of endometrium prior to conception (By similarity).  Acts as a water channel enabling passive water transport in response to the osmotic gradient created upon sugar and Na(+) uptake.  Has high water conductivity comparable to aquaporins and therefore is expected to play an important role in transepithelial water permeability, especially in the small intestine.
What are the official names of this protein?
Sodium/glucose cotransporter 1, Na(+)/glucose cotransporter 1, High affinity sodium-glucose cotransporter, Solute carrier family 5 member 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: PHNX_PSEPK
Sequence: MNYNNPTQLQAAILDWAGTVVDFGSFAPTQIFVEAFAEFDVQVSIEEARGPMGMGKWDHIRTLCDVPEIAERYRKVFGRTPTDDDVTAIYNRFMPLQIEKIAVHSALIPGALDTLTGLRQDGLKIGSCSGYPKVVMDKVVELAAQNGYVADHVVATDETPNGRPWPAQALANVIALGIDDVAACVKVDDTVPGILEGRRAGMWTVALVCSGNALGLTWEGFRALSAEKLESERQRIHALFAGSRPHYLIDTINDLPEVIADINRRLAKGEMPQAF
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: KHSE_HELPJ
Sequence: MVVSVPATSANLGPGFDCLGLSLNLRNRFFIEPSNIHAVKLVGEGEGIPKFLTNNIFTKVFYEILKKHGNDGSFKFLLHNKVPITRGMGSSSAMIVGAVASAFAFLGFAFDRENILNTALIYENHPDNITPAVFGGYNAAFVEKKKVISLKTKIPSFLKAVMVIPNRVISTKQSRHLLPKRYSVQESVFNLSHASLMTMAIVQGKWDLLRCCSKDRMHQYKRMQTYPVLFAIQKLALENNALMSTLSGSGSSFFNMCYEEDAPKLKQVLSKKFPKFRVAVLDFDNDGVLIEKD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSSA_DIACI
Sequence: MSGGLDILSLKEDDVTKMLGAQTHIGSENSDYQMEQYVYKRRNDGVHILNLRRTWEKLLLAARAIVAIEHPADVFVISSRPIGQRAVLKFASYTGATPIAGRFTPGAFTNQIQAAFREPRLLVVTDPHTDHQPITEAAYVNIPVIAFCNTESPLRFVDIAIPCNNKSPHSIGLMWWLLAREVLRFRGTIPREPKWDVVVDLFFYRDPEEAEKEEQAGKESAAAIADKPADEFAAHAPTESWNDTVVPSADLAPQSWAEESASIPQYAPAPQAAAAPVADDWTTPVGADDWGQDWSNSTSQW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein SA.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBID_CHRSD
Sequence: MKYRDLRDFIAALEARGELTRVTAEVDPYLEITEICDRTLRAGGPALLFENVKGHAMPLLGNLFGTPERVALGMGQDSTAALREVGELLAFLKEPEPPKGFRDAWEKLPIFKQAMSMGPKTLRKAPCQEVILEGDDVDLDRLPIQHCWPGDVAPLVTWSLVVTKGPNKTRQNLGIYRQQKLGKNRLIMRWLSHRGGALDFQEWQSAHPGEPFPVAVALGADPATILGAVTPVPDNLSEYAFAGLLRGSRTELVKCGHADLEVPASSEIVLEGYIYPDDTAPEGPYGDHTGYYNEVETFPVFTVERITHRRDPIYHSTYTGRPPDEPAILGLALNEVFVPILRKQFPEIVDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMMGVWSFLRQFMYTKFVIVLDDDVDARNWEDVIWAITTRMDPARDTVMVENTPIDYLDFASPTAGLGSKMGLDATTKWAGETQREWGTPIVMDEAVKRRVDERWGEYGIATPPPPPRHSPPSDERGHDDV
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NTPP_PROM3
Sequence: MLMLASASPARHRLLQQALIPHQVMVSGVDEETIHHLDPVRLVQHLAEAKAGVVRQQIEAALPVLGCDSVLEFDGTVFGKPATAVEASSRWQRMAGAWGLLHTGHCLLSVNGERLSETVTTRVLFSALSDSEIEAYVATGEPLLCAGGFALEGQGGLMVERLEGCFSNVIGLSLPLLRRWLLVINE
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPB1_MOUSE
Sequence: MGKKGKVGKSRRDKFYHLAKETGYRSRSAFKLIQLNRRFQFLQKARALLDLCAAPGGWLQVAAKFMPVSSLIVGVDLVPIKPLPNVVTLQEDITTERCRQALRKELKTWKVDVVLNDGAPNVGASWVHDAYSQAHLTLMALRLACDFLARGGCFITKVFRSRDYQPLLWIFQQLFHRVQATKPQASRHESAEIFVVCQGFLAPDKVDAKFFDPKFAFKEVEVQAKTVTELVTKKKPKAEGYAEGDLTLYHRTSVTDFLRAANPVDFLSKASEISIDDEELAQHPATTEDIRVCCQDIKVLGRKELRSLLNWRTKLRRYVAKKLKEQAKALDISLSSEEEEEGDEEEAVAETKQAPEEEEEREEEQLNRTLAEMKAQEVAELKRKKKKLLREQRKQRERVELKMDLPGVSIADEGETGMFSLRTIRGQQLLEEVTQGDMNAADTFLSDLPRDDIYVSDAEDDDDTSLESDLDPEELAGVRTHSDLKEQKYLRFTQVDDNKEEEGENPLLVPLEEKAVLQEEQASLWFSKDGFSGIEDDADEALEISQAQLLYKSRQKEQQPTDPPPPPTNLKTEKKSPQGQNEVPKETEAILGTEAVTDPGGEERGNSSDSDSSSSEDEDSWKVSRGVKRGRGSKADEDGFEVVPIQDPVKYRILDPEGLALGAVIASSKKAKRDLIDNSFNRYAFNEEEGELPEWFAQEEKQHRIRQLPVDKKEVEHYRKRWREINARPIKKVAEAKARKKRRVLKKLEQTKKKAEAVVNTVDISEREKVAQLRSLYKKAGLGKEKRQVTYVVAKKGVGRKVRRPAGVKGHFKVVDSRMKKDQRAQQRKEQKKKHKRK
What is the function of this protein?
RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
What are the official names of this protein?
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3, Protein ftsJ homolog 3, Putative rRNA methyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: BACR_HALS4
Sequence: MCCAALAPPMAATVGPESIWLWIGTIGMTLGTLYFVGRGRGVRDRKMQEFYIITIFITTIAAAMYFAMATGFGVTEVMVGDEALTIYWARYADWLFTTPLLLLDLSLLAGANRNTIATLIGLDVFMIGTGAIAALSSTPGTRIAWWAISTGALLALLYVLVGTLSENARNRAPEVASLFGRLRNLVIALWFLYPVVWILGTEGTFGILPLYWETAAFMVLDLSAKVGFGVILLQSRSVLERVATPTAAPT
What is the function of this protein?
Light-driven proton pump.
What are the official names of this protein?
Bacteriorhodopsin, BR.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 5MP2_CHICK
Sequence: MNQKQQKPTLSGQRFKTRKRDEKERFDPTQFQDCIIQGLTETGTDLEAVAKFLDASGAKLDYRRYAETLFDILVAGGMLAPGGTLADDMTRTDVCVFAAQEDLETMQAFAQVFNKLIRRYKYLEKGFEDEVKKLLLFLKGFSESERNKLAMLTGILLANGTLNASILNSLYNENLVKEGVSAAFAVKLFKSWINEKDINAVAVSLRKVNMDNRLMELFPANKQSVEHFSKYFTEAGLKELSEYVRNQQTIGARKELQKELQEQMSRGDPFKDIILYVKEEMKKNNISEQTVIAIIWSSVMSTVEWNKKEELVAEQAIKHLKQYSPLLAAFTTQGQSELTLLLKIQEYCYDNIHFMKAFQKIVVLFYKAEVLSEEPILKWYKDAHLAKGKSVFLEQMKKFVEWLKNAEEESESEAEEGD
What is the function of this protein?
Translation initiation regulator which may repress repeat-associated non-AUG (RAN) initiated translation probably by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function (By similarity).  Enhances histone H4 gene transcription but does not seem to bind DNA directly (By similarity).
What are the official names of this protein?
eIF5-mimic protein 2, Basic leucine zipper and W2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the BZW family.
Protein: C1437_CAMJE
Sequence: MQANKNIQKLTPYLSIPHKIWNSSQSNILKLDWNEATIPPSPYVIESIKKFLVNGNLNWYPNTKNLYLLDKIAEYTKQINSSFVELFEGSDSAHECIIDVFLDKCDKIGIVSPTYDNFRSRANGVGIETISFTLDDNFNLDFDSLEYFIHEKRIKLLYLCNPNNPTGKSYNIQKIKSLIINNPNVMFIIDEAYYEFTSQSVCDLVEQCNNLIITRTFSKAFALASFRIGYIISHPENIESINKLRNPKSVPMLSQIAANAALEDLQYMRDYVDEVSCARMEFVKFLNTLTTGGGGIFNDSVANFVLIQNENISLFVGFLEKEGIFIRNYSHLISKNCRISIGTRNQMSYVAEKIQEFAKKQGGFHLV
What is the function of this protein?
Pyridoxal phosphate (PLP)-dependent transaminase involved in the biosynthesis of amidated D-glucuronic acid structures found on the capsular polysaccharide (CPS) of C. jejuni.  Catalyzes the transamination of dihydroxyacetone phosphate (DHAP) to (S)-serinol phosphate in the presence of L-glutamate.  Less active with L-aspartate.  No activity with dihydroxyacetone or L-alanine.
What are the official names of this protein?
Dihydroxyacetone phosphate transaminase Cj1437c, Capsule polysaccharide biosynthesis protein Cj1437c, PLP-dependent transaminase Cj1437.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
Protein: EGFLA_HUMAN
Sequence: MDLIRGVLLRLLLLASSLGPGAVSLRAAIRKPGKVGPPLDIKLGALNCTAFSIQWKMPRHPGSPILGYTVFYSEVGADKSLQEQLHSVPLSRDIPTTEEVIGDLKPGTEYRVSIAAYSQAGKGRLSSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSEVALSWKPGASEGSAPIQYYSVEFIRPDFDKKWTSIHERIQMDSMVIKGLDPDTNYQFAVRAMNSHGPSPRSWPSDIIRTLCPEEAGSGRYGPRYITDMGAGEDDEGFEDDLDLDISFEEVKPLPATKGGNKKFLVESKKMSISNPKTISRLIPPTSASLPVTTVAPQPIPIQRKGKNGVAIMSRLFDMPCDETLCSADSFCVNDYTWGGSRCQCTLGKGGESCSEDIVIQYPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAIIVSETKIKLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYWLVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGADVGECSSGICDEASCIHGGTCTAIKADSYICLCPLGFKGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWHELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKIILNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQKECGNYCLNTIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGALVFSYNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSGKITVDDYGARTGKSPGMMRQLNINGALYVGGMKEIALHTNRQYMRGLVGCISHFTLSTDYHISLVEDAVDGKNINTCGAK
What is the function of this protein?
Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception.  Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse.  Promotes matrix assembly and cell adhesiveness.
What are the official names of this protein?
Pikachurin, Agrin-like protein, EGF-like, fibronectin type-III and laminin G-like domain-containing protein.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Synaptic cleft. Presynaptic active zone. Note=Detected in the synaptic cleft of the ribbon synapse around the postsynaptic terminals of bipolar cells. Colocalizes with BSN, CTBP2 and DAG1 in photoreceptor synaptic terminals.
Protein: ARI3A_DANRE
Sequence: MVDNTSIATKSALQAAFSSASSLPLLVSSPGAHGQSGGGGGMKLEAVMENLQRQQAARLALEEKLRQAEKEKDIRSMVESQIQQQALAFRHYQAAVRGAFAAGVPNSSSGHPLERRAESDIDDEDDEDDDPELDRGMDDEERDMDEDDSMNEGGGDEDLEGPLAHYPPRHAVYPGAGQSPKSTPIHLSRVQPPYPAPRQAESPSALAPQAQSQHHEWTYEEQFKQLYELDDDEKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLYTLYKLVTEKGGLVEVINKKIWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECEKRGLSSPGELQAAIDSNRREGRRQSYGSTLFNYSPVGTPTLLASPKLQMPHISMPTPNGGHMTQTPGIKKEDSMLSSCLTNRVGIPMSLAGHHSAAQAAAAAAVQAAALEQLREKLESGEPPEKKVMLMAEEQQRIMQHALQQNLFAMATQLPMNIKLNNRDDRQETALNLSTNGISSINMSIEINGVVYTGVLFARKPAIGFMPSSQRVHHQHSSQGKSNSPGLSSHIQPSSSASSSASSHGPATSP
What is the function of this protein?
Transcription factor.
What are the official names of this protein?
AT-rich interactive domain-containing protein 3A, ARID domain-containing protein 3A, Bright homolog.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.
Protein: COAX_DESAH
Sequence: MLLVIDVGNTNTVLGVFNGNTLIQDWRIRTIRESTVDEFNLLAKALFVDKKIDLSTIKRTVISSVVPPINSILDTFCTRYLNQKPLWIDPASVKNLMPICYSNPAEVGADRIVNAVAAFERYKTSMIIIDFGTATTFDAISAKGEYLGGAITPGVMISAEALFQRASKLPRVEIFRRPQNVIGKNTIDSIKSGIIYGNGALVDGMVKRMSKEMGTTPKVIATGGLAVLIADASETIEIVDNALTLEGLRIIADQPVFSEGQR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_CALBD
Sequence: MNLEVEIAGIKLKNPVIAASGTFGFGREYSKLIDISEFGAICTKGITLKKRIGNPQPRLCEVYAGIINSVGLENPGVEAFINDELPFLKSFDTKIIANINGFSKEEFVELTKILTSLVDMIEVNLSCPNVKEGGMVFGKDPKKVYEITKSVKDVASCPIIVKLTPNVTDITQLAVAAENAGADAISLINTVSAMAIDIETRKPLIKMVTGGLSGPAIKPIAVRMVYECFKKVRIPIIGMGGIMNYKDAIEFFIAGATAIQIGTVNFINPKAVCEIKEGIEAYLERKGFKSIKELVGSINI
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_HELAH
Sequence: MAIGMSELKKGLKIELGGVPYRIVEYQHVKPGKGAAFVRAKIKSFLDGKVIEKTFHAGDKCEEPNLVEKTMQYLYHDGDAYQFMDIESYEQIALSDSQVGEASKWMLDGMQVQVLLYNDKAISVDVPQVVALKIVETAPNFKGDTSSASKKPATLETGAVVQVPFHVLEGEIIKVNTETEEYLEKVK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDM8_DANRE
Sequence: MASVWTDIRAVLPSTVSEFPLDFSEKIDLSVLKCLELSRDQLYSEADCPVSAERAQIIIDYSWEKLNIGTWRDVDKEWRRVYSYGCLFKVLSLCHGNPPQNIIQEAVRTCDMSLLMGAAIMDNILQRLVGILRNKIKTTCPNKAERSEEPFSKKRKHDCKSEPVLNPTKEVPRIHCPSLERFRSDFLDPKKPVIIEGITDLWPAFTQHPWSIDYLRTVAGCRTVPIEVGSKYTDEEWSQKLITVNDFIDRYITGTEEDGVGYLAQHQLFDQVPELKEDIRIPDYCCLGEGDEDDITINAWFGPGGTVSPLHQDPQQNFLAQVVGRKYIRLYSPEDTKSLYPHESQLLHNTSQVEVENPDLVKFPDFSRASYEECVLCPGDVLFIPLQHWYYVRSLELSFSVSFWWS
What is the function of this protein?
Histone demethylase required for G2/M phase cell cycle progression (By similarity).  Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator (By similarity).  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
Lysine-specific demethylase 8, JmjC domain-containing protein 5, Jumonji domain-containing protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: AZOR_MYCS5
Sequence: MAKVLVLSGGLSEKEKSYSSQMLDLFVKTYKEVHPNDELEFVDLNTTKHAEVFLSRNTFATYWKDVESDKWIDKLKAADKVILSCSMTNFGPTAVVKNFIDSVAVANKTFSYKYSKKGDAVGLLDHLRVMIVTTQGAPKDWYLWGSHTNWLIGTWKFLGAKYVDTFELNGTKLSVFADKKPYDVVEEFRQDALEKAKQF
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: GPR22_RAT
Sequence: MCFSPVLEINMQSESNVTVRDDIEDIDTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLISSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLERNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMTSIWIFSFFSFLIPFIEVNFFSLQSGNAWENKTLLCVSTSEYYTELGMYYHLLVQIPIFFFTVIVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLTTHETTDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKVTYEDSEIREKCLVPQVVTD
What is the function of this protein?
Orphan G-protein coupled receptor.  Seems to act through a G(i)/G(o) mediated pathway (By similarity).  May be involved in ciliogenesis (By similarity).
What are the official names of this protein?
G-protein coupled receptor 22.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.