PharMolix/UniProtQA huggingface dataset:
Protein: RLUD_SHIFL
Sequence: MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIVINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDWL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA.
What are the official names of this protein?
Ribosomal large subunit pseudouridine synthase D, 23S rRNA pseudouridine(1911/1915/1917) synthase, rRNA pseudouridylate synthase D, rRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: RPPH_FRATT
Sequence: MIDKSGYRANVAIVLLNKQNRVFWGQRRNRTSWQFPQGGVATGETPLQAMYRELHEEIGLRPQDVEVIASTRDWYKYDIPDSLVRTKEPICIGQKQKWFLLKLKSPESYIDLDANDSPEFDNWRWVSYWYPINHVVYFKQEVYRKALTYFKEYIA
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PANC_WIGBR
Sequence: MLIIKKSSELTCVIKNLKKKNKSKIALIPTMGNLHRGHLELIKIGKLKSNILIISIFINPAQFSNSKDFRNYPKTLNEDIKKLIEYKVDILFCPTLKSMYPFGYKNHTLVNVVQYSSILDGKTMSNHFIGVATIISKLFNLINPDIAIFGQKDFQQLIMIRQLVLHMNYNIKILSAPIIRCFDGLALSSRNRHLSLEERKKAPKIYNILLELSKKIKLNKLYNLKKDYDAILKNYLIKLNNYGFKVEVLSIRNAKNLMPIDENSKQAVILCSAKIGSIRLVDNIKIKL
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_ACIBY
Sequence: MKTIKVTQTKSSSHRLKNHKLCLQGLGLRRIGHTVEVQDTPSNRGMINKVYYMVSVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: VE6_HPV05
Sequence: MAEGAEHQQKLTEKDKAELPLSIRDLAEALGIPVIDCLIPCNFCGNFLNYLEACEFDYKRLSLIWKDYCVFACCRVCCGATATYEFNQFYEQTVLGRDIELASGLSIFDIDIRCQTCLAFLDIIEKLDCCGRGLPFHKVRNAWKGICRQCKHFYHDW
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: MCHR1_MOUSE
Sequence: MDLQASLLSTGPNASNISDGQDNFTLAGPPPRTRSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT
What is the function of this protein?
Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.
What are the official names of this protein?
Melanin-concentrating hormone receptor 1, MCH receptor 1, MCH-R1, MCHR-1, G-protein coupled receptor 24, MCH-1R, MCH1R, MCHR, SLC-1, Somatostatin receptor-like protein.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SNF7_ASHGO
Sequence: MWSYLFGSGNAKQKKELPKKAILELREHIQLLSKKQAHLQTQMTSQEESARHFLSKGNKNMAKAALKRKKVFESQLLKIDKQVDSLEQQLYSIENANLNLETMKAMKQGASAMKHIHEGLDVERVDETMDEIREQVELGEEISEAISRPLYTGVNEIDEDELDEELDMLAQEEVARKVMEPGAAVPAAAPATKVSLPSVPSSDMPQQDRGQPVTLGMDQEEDEDERALRELQAEMGL
What is the function of this protein?
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).  Also required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH (By similarity).
What are the official names of this protein?
Vacuolar-sorting protein SNF7, Vacuolar protein-sorting-associated protein 32.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: RGTB_RHIL3
Sequence: MTESNRRDISWIFALLAAYFVLQVGVRLATSHSLDLDEAEQAFRSQWLAAGYGPQPPFYNWLQYTVFQFAGVSLTALSIVKNLLLFISYLLYGLTARLVLRDKALVAIATLGLLTIPQMAFEMQRDLTHTVAVFFSASIFFYGFIRSLKQPSLASYLIAGIGIGFGLLAKYNFAILPAAALIAALSDARLRPRIFDWRLGLTAAVALVITLPHLFWLKDNLDFATARTLEKMTASGDASYLTQVAMGVSSLALAIISFAALTVAVFAIVFGKSLRPALGSGSEWTRLLERMMLVFLAGILLLIVFGGAAGIKDRWLVPMLFILPLYFCLKIEAAGVETGKALRRFIPVVAVIMIGVPAALYGSVAAARFTGHYERLNRPYAGMLEILRKQAEPAAILAGDSLLAGNLRQDIPGVPILSADYPGFNPDLTSRRPLLLVWLLPKGGSEALPPDMAEWLQANLGTSAPEASVIDVPYFYGRGDDRYRFGYAWVNQPG
What is the function of this protein?
Involved in the modification of the lipopolysaccharide (LPS) inner core.  Catalyzes the transfer of a galacturonic acid (GalA) residue to the 5-position of the outer Kdo (3-deoxy-D-manno-octulosonic acid) residue of the LPS inner core, using dodecaprenyl phosphate-GalA as the donor substrate.  Acts after the other GalA transferase RgtA.
What are the official names of this protein?
Lipopolysaccharide core galacturonosyltransferase RgtB, LPS core GalA transferase RgtB, Dodecaprenyl phosphate-beta-galacturonate:lipopolysaccharide core alpha-galacturonosyltransferase RgtB, Dodecaprenyl-P-GalA:LPS core galacturonosyltransferase RgtB, Galacturonic acid transferase RgtB, GalAT RgtB.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYB_PETPH
Sequence: MTNIRKTHPLIKIVNHSFIDLPTPSNISAWWNFGSLLGLCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYIHANGASMFFICLYLHVGRGLYYGSYTYFETWNIGVILLFTIMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIVTALVMVHLLFLHETGSNNPSGLISDSDKVPFHPYFTIKDILGALLLTLSLFLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHMSKQRGMMFRPLSQCLFWILAADLFTLTWIGGQPVEHPFIIIGQTASILYFTIILIILPLVSMLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SUSD6_HUMAN
Sequence: MCHGRIAPKSTSVFAVASVGHGVFLPLVILCTLLGDGLASVCPLPPEPENGGYICHPRPCRDPLTAGSVIEYLCAEGYMLKGDYKYLTCKNGEWKPAMEISCRLNEDKDTHTSLGVPTLSIVASTASSVALILLLVVLFVLLQPKLKSFHHSRRDQGVSGDQVSIMVDGVQVALPSYEEAVYGSSGHCVPPADPRVQIVLSEGSGPSGRSVPREQQLPDQGACSSAGGEDEAPGQSGLCEAWGSRASETVMVHQATTSSWVAGSGNRQLAHKETADSENSDIQSLLSLTSEEYTDDIPLLKEA
What is the function of this protein?
May play a role in growth-suppressive activity and cell death (PubMed:24652652).  May be involved in the production of chemokine molecules in umbilical vein endothelial cells (HUVECs) cultured in THP1 monocyte LPS-induced medium (PubMed:20236627).  Plays a role in preventing tumor onset (By similarity).
What are the official names of this protein?
Sushi domain-containing protein 6, Drug-activated gene overexpressed protein.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PHNW_PSEPF
Sequence: MSTAAPILLTPGPLTTSARTRQAMMVDWGSWDDRFNQLTASLCEQLLAILNGADSHHCVPLQGSGTFAVEAAIGTLVPRDGKVLVLINGAYGKRLAKICEVLGRSFSTFETAEDEPTTAADVDRLLCADSDITHVALIHCETSTGILNPLPEIAQVVEQHGKRLIIDAMSSFGALPVDAQKVPFDALIAASGKCLEGVPGMGFVFARKESLAAAAGNSHSLAMDLFDQHSYMKKTGQWRFTPPTHVVAALHEALLQYNEEGGLPARHARYAANCQALMEEMGKLGLRSFLPAAIQAPIIATFHAPKDPRYQFKDFYERVKAKGYILYPGKLTQVETFRVGCIGHVTPAQMREAVAAVSEVLREMEVLDI
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: SAHH_MEDSA
Sequence: MALLVETTTSGREYKVKDMSQADFGRLEIELAEVEMPGLMSCRTEFGPSQPFKGARITGSLHMTIQTAVLIETLTALGAEVRWCSCNIFSTQDHAAAAIARDSAAVFAWKGETLQEYWWCSERALDWGPGGGPDLIVDDGGDVTLLIHEGVKAEEVFEKTGQLPDPSSTDNAEMQIVLTIIRDGLKTDPKRYQKMKTRIVGVSEETTTGVKRLYQMQASGTLLFPAINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMIAGKVAVVCGYGDVGKGCAAALKQGGARVIVTEIDPICALQALMEGLQVLTLEDVISEADIFVTTTGNKDIIMVSDMKKMKNNAIVCNIGHFDNEIDMHGLETYPGVKRITIKPQTDRWVFPETKSGIIVLAEGRLMNLGCATGHPSFVMSCSFTNQVIAQIELWKEKTSGKYEKKVYVLPKHLDEKVAALHLGQLGAKLTKLSKDQADYISVPVEGPYKPAHYRY
What is the function of this protein?
Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, AdoHcyase, S-adenosyl-L-homocysteine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
Protein: L_MABVR
Sequence: MQHPTQYPDARLSSPIILDQCDLLTRSLGLYSHYSHNPKLRNCRIPYHIYRLRNSTALKTFLQNCSILTVPFHSIWDHIITSIQHDAINHINDFKYLLPSELIKYANWDNEFLRVFLNKILRLDHAFTNSAKLQCEDFSPKENPYYWGMLLLVHLSQLARRIKGQRGSLRSNWKFIGVDLELFGIADFVIFKVPIKAIIRNATSLQASKPGLKTWYRDQNLTPYLCDDEFVVSIASYECFIMIKDVFIERYNTWEICARAWVEDNEEADYPPLGILRDLYNQGDQIITMYLEDGFKLIKHLEPLCVSCIQTYGIFTPRKYWFQSQMIKSYYDELQSLNLKLQIPDNRTECAQNFIKTIIQAKLTPQQYCELFSLQKHWGHPVLYNDVALDKVKKHAQSTKILKPKVMFETFCVFKFIVAKNHYHSQGSWYKTTHDLHLTPYLRQHIVSNSFPSQAEIYQHLWEWYFVEHEPLFSTKIISDLSIFIKDRATAVNRECWDSVFDRSVLGYNPPVRFQSKRVPEQFLGQADFSLNQILDFAEKLEYLAPSYRNFSFSLKEKELNIGRTFGKLPYRVRNVQTLAEALLADGLAKAFPSNMMVVTEREQKEALLHQASWHHNSASIGENAIVRGASFVTDLEKYNLAFRYEFTRHFIDYCNRCYGVKNLFDWMHFLIPLCYMHVSDFYSPPHCVTENNRNNPPDCANAYHYHLGGIEGLQQKLWTCISCAQITLVELKTKLKLKSSVMGDNQCITTLSLFPIDAPNDYQENEAELNAARVAVELAITTGYSGIFLKPEETFVHSGFIYFGKKQYLNGVQLPQSLKTMARCGPLSDSIFDDLQGSLASIGTSFERGASETRHIFPSRWIAAFHSMLAVNLLNQNHLGFPLGFSIDVSCFKKPLTFSEKLIALITPQVLGGLSFLNPEKLFYRNISDPLTSGLFQLRNALEFLRKEELFYILIAKKPGLADASDFVMNPLGLNVPGSREIITFLRQTVRENITITSQNRIINSLFHIGSDLEDQRVCEWLLSSNPVMSRFAADIFSRTPSGKRLQVLGYLEGTRTLLASRTISLTTEGTMLMRLRELTKSRWKSWFSYIDALDDDLSESLEKFICTVDVANFLRAYSWSDVLKGKRLIGATLPCLLEQFNVKWVNLSEDLKEQFKLSSDLGSPTDLLQYDCNGLHSKGADNAELNYVSCALDRKIVQKHPSDNRLAWTIGNRAPYIGSRTEDKIGYPPLRVNCPSAALKEAIEMVSRLLWVTQGTADREKLLIPLLNSRVNLDYQTVLNFLPTHYSGNIVHRYNDQYGQHSFMANRMSNTSTRAIISTNTLGKYAGGGQAAVDSNIIFQNTINLGVAVLDITLSLSKLSSTSNVSFRLMLSKCCTRHVPSEYLFFDKPLDVDLNKYMDNELVYDNDPLCSGIKGRLGRVSRSTLSLSLNVSDIGSYDFPTIAAWTLGETIIGSIFSDESSQSTDPISSGCTKTFVTHFLVYPVESIFYAFGANLIVESLSLSRINSIKSLSDLTFLISSTIRNLSHRSLRILQSTFRHELVLTRLAHHIPLISLMLGGSAGEKSSSDAVRLFLTASYQNFINNFSCLMRKNQSPLPVWLYFPSEGQQLKPILKILQRLSCLLTTKKVQNHRPVADTCFLTDNFWVYPSKSTRTNHYYASLNYWRDKANKIKNTSFSHLINYSFSEPSLHASSISSSQEVVNLKHTSRLDETPNMSERAQSTNHEPTALQEVCTEIPYSEQDPAKSYLLLENTRFRDDQKILRHDQKAERGEPLSLQVSSRGCLQALTCPHHPSPSQTTTEPLSMLRNCDAIKAALRSETNDPRLMSSILDMRSLKTPMRIESRNTSLLQPSECLSTSKGKSVLSREQASYLYVDCSNISSISLDSGFRNMSDRNQVQMLINTYKRDLYTCFDSNQFCRFTGVVSSMHYKLYDLLPAGKLGKAICLAEGEGSGARLLLKWKETDYLFFNTLATDSQQEAEILSGRVIPRMLYNIDKLSVLLESRKLILNNLTIQITDITNPLWLDSVIQYLPEDSDILTMDAETTKEETREQLYKTIINIWARTSPNIPKTSIIKVFLLDYGGTLFLMKNAIQYYGQVQLKKPYSSNAKNSEWYLCCGKRRVQRLRVDFPDQVGIFLICKAMSRQRQAIPYWLKHIEKNYPASLHEFFITLGFPSLESSFCHRYTIPFTEGTALFHKVQSYVRQGRQHLHSLMLDYENNSPLLDLRNHFICSLRGKITKYYNDILKLNLVVRAVERGKNWSQLVESLPNMHSVCITHVDHECIGCERRLLLKLDFVRNTKIAEQKLLNRVIGYILFFPFGFSRPK
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: ACE2_FELCA
Sequence: MSGSFWLLLSFAALTAAQSTTEELAKTFLEKFNHEAEELSYQSSLASWNYNTNITDENVQKMNEAGAKWSAFYEEQSKLAKTYPLAEIHNTTVKRQLQALQQSGSSVLSADKSQRLNTILNAMSTIYSTGKACNPNNPQECLLLEPGLDDIMENSKDYNERLWAWEGWRAEVGKQLRPLYEEYVALKNEMARANNYEDYGDYWRGDYEEEWTDGYNYSRSQLIKDVEHTFTQIKPLYQHLHAYVRAKLMDTYPSRISPTGCLPAHLLGDMWGRFWTNLYPLTVPFGQKPNIDVTDAMVNQSWDARRIFKEAEKFFVSVGLPNMTQGFWENSMLTEPGDSRKVVCHPTAWDLGKGDFRIKMCTKVTMDDFLTAHHEMGHIQYDMAYAVQPFLLRNGANEGFHEAVGEIMSLSAATPNHLKTIGLLSPGFSEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKEQWMQKWWEMKREIVGVVEPVPHDETYCDPASLFHVANDYSFIRYYTRTIYQFQFQEALCRIAKHEGPLHKCDISNSSEAGKKLLQMLTLGKSKPWTLALEHVVGEKKMNVTPLLKYFEPLFTWLKEQNRNSFVGWNTDWRPYADQSIKVRISLKSALGDEAYEWNDNEMYLFRSSVAYAMREYFSKVKNQTIPFVEDNVWVSNLKPRISFNFFVTASKNVSDVIPRSEVEEAIRMSRSRINDAFRLDDNSLEFLGIQPTLSPPYQPPVTIWLIVFGVVMGVVVVGIVLLIVSGIRNRRKNNQARSEENPYASVDLSKGENNPGFQHADDVQTSF
What is the function of this protein?
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis.  Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor angiotensin II.  Also removes the C-terminal residue from three other vasoactive peptides, neurotensin, kinetensin, and des-Arg bradykinin, but is not active on bradykinin.  Also cleaves other biological peptides, such as apelins, casomorphins and dynorphin A.  Plays an important role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 in intestine, regulating trafficking, expression on the cell surface, and its catalytic activity.
What are the official names of this protein?
Angiotensin-converting enzyme 2, ACE-related carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M2 family.
What are the subcellular locations of this protein?
[Processed angiotensin-converting enzyme 2]: Secreted. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cell projection, cilium. Apical cell membrane. Note=Detected in both cell membrane and cytoplasm in neurons.
Protein: RS16_PSEA6
Sequence: MVTIRLQRGGAKKRPFYQVVVADSRRSRDGRFIENIGFFNPTAQGQEERLRLDLDRVEHWVGNGAGLSDRVARLVKDAQKAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: GUAAA_METAC
Sequence: MRELKILVVNNYGQFCHLIHRAVRDLDMDTKIIPNVTPIEDILAEEPDGLILSGGPEMERAGLCFDYVREIDIPILGICLGHQAIALAYGGHVHSGKKGGYAEIEIEVIEEDDILRGLGPKITVWASHADEVAILPEGFIHLARSDICEIEAMRHPTKPIYGVQWHPEVSHTKKGDELLTNFFEVCDRY
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit A, Glutamine amidotransferase.
Protein: GCS21_STRAW
Sequence: MRTVGVEEELLLVDPETGEPKALSTAVLARAEQVDPDQDVFEKELHGQMLEFATHPQTDMAALGAEIVRCRKEAARHAGEAGCAVAALATSPLPVSPSIAMNRRYQWMAEQYGIAMQEQLTCGCHVHVAVESDEEGVAVVDRIRPWLPVLVALSANSPFWQGRDSSYESYRSRVWGRWPSAGPTELFGSPERYHRQVADMVATGVILDDGMVYFDARLSHRYPTVEIRVADVCLHPDTAQLIATLARGLVESAARDWRAGREPEDHSVSLLRLAAWQAARAGLSGELLHPVTMRRLRAESVVRALLEHVGDALADAGDLDLAHEAVAELLERGNGARVQRELLERTGSLRDTVTECVRQTQG
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-1, Gamma-glutamylcysteine synthetase 2-1, GCS 2-1, Gamma-GCS 2-1.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: YR564_MIMIV
Sequence: MVAFYGIFLFGTVYLFGLAKLFYQYVSNKLVSTVHIVTDSSNELVESTEPTEIIEVDDVEIIQPIEFSEHIESSEPIESTEPISLSEREKIAEIRMKKFSQRSKISNIINKKRVQTQFSNTDYSDRHRDQVLRDWMN
What are the official names of this protein?
Uncharacterized protein R564.
Protein: BXLB_ASPTN
Sequence: MYSSNSRRAASILACIVSLTQLGFAQSPFPDCENGPLSKNAVCDTTLDPVTRAQALLAAMTLEEKINNTQYNSPGVPRLGLPAYNWWSEALHGVAGSPGVHFADSGNFSYATSFPSPITLGAAFDDDLVKQIATVIGTEGRAFGNAGHAGLDYWTPNINPYRDPRWGRGQETPGEDPFHTSRYVYHLIDGLQDGIGPEKPKIVATCKHFAGYDIEDWEGNERYAFDAVISDQDMAEYYFPPFKTCTRDAKVDAVMCSYNSVNGIPTCADPWLLQTVLREHWEWEGVGHWVTSDCGAIDNIYKDHKYVADGAHAAAVAVNAGTDLDCGSVYPQFLGSAISQGLLGNRTLDRALTRLYSSLVKLGYFDPAADQPYRSIGWSDVATPDAEQLAHTAAVEGTVLLKNDGTLPLKKNGTVAIVGPYANATTQLQGNYEGTAKYIHTMLSAAAQQGYKVKYAPGTGINSNSTSGFEQALNAAKGSDLVIYFGGIDHEVEAEALDRTSIAWPGNQLDLIQQLSDLKKPLVVVQFGGGQVDDSSLLSNAGVNGLLWAGYPSQAGGAAVFDILTGKTAPAGRLPVTQYPEEYVDQVPMTDMNLRPGPSNPGRTYRWYDKAVIPFGYGMHYTTFDVSWKRKNYGPYNTAAVKAENAVLETFSLQVKNTGKVTSDYVALVFLTTTDAGPKPYPIKTLVGYQRVKAIRPGERKVVDIDVTVGSVARTAANGDLVLYPGSYKLQVDVEKDYPTAGFKIAGKEVVLDHFPQPPRNATKA
What is the function of this protein?
Xylan 1,4-beta-xylosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Probable exo-1,4-beta-xylosidase bxlB, 1,4-beta-D-xylan xylohydrolase bxlB, Beta-xylosidase bxlB, Xylobiase bxlB.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MALE_MALAU
Sequence: MTAGPMGNKSTSDIDSVLVYKSLSRYLKFSENEEGWWHKTAPLLNKILAAAKYDVHLQYRYLVFYYAACVSALGPYPQRFSSSITRSGLPVEFSVNYQNNSKPIVRIGYEPISHLSGTERDPYNHKTASEIVATLSKIQPDFDPRLFNYFVHQLSVNKAESDVLNGANVEGSEMKSQTAFGFDLVNGEISVKGYAFPAMKCQVSQQSLSQLLKAAINGLKGEFDCAFGLVDEYMERCGGYNQFSFVSWDCVVPAKSRFKVYGVHNDVTWKKIEDIWTLGGQATSGNVTKGLELLKELWTLIDLDEGERGYTGRFDDANDNGSNIQSPMVWNYELRPNNPWPLAKFYFPVHGENDMKIVKGLARFFENRGWTELARSYVQTVSSFFPDRDLNQTQRLVSWISFAYTEKTGVYLSVYYHSSADYLWISESGEKRGQGDGA
What is the function of this protein?
Prenyltransferase; part of the gene cluster that mediates the biosynthesis of malbrancheamide, a dichlorinated fungal indole alkaloid that belongs to a family of natural products containing a characteristic bicyclo[2. 2. 2]diazaoctane core (PubMed:23213353, PubMed:31548667, PubMed:28777910).  The first step of malbrancheamide biosynthesis involves coupling of L-proline and L-tryptophan by malG, a bimodular NRPS, to produce L-Pro-L-Trp aldehyde through reductive offloading (PubMed:23213353, PubMed:31548667).  This compound undergoes spontaneous cyclization and dehydration to give a dienamine which is reverse prenylated at C-2 by malE (PubMed:31548667).  The other prenyltransferase present in the cluster, malB, displays modest activity, suggesting that may be a redundant gene in the pathway (PubMed:31548667).  Subsequently, a [4+2] Diels-Alder cyclo-addition catalyzed by the bifunctional enzyme malC forms the characteristic bicyclo[2. 2. 2]diazaoctane ring of premalbrancheamid (PubMed:31548667).  Finally, the flavin-dependent halogenase malA catalyzes the iterative dichlorination of the indole ring of premalbrancheamide to yield C-9 monochlorinated malbrancheamide B, C-8 monochlorinated isomalbrancheamide B, and dichlorinated malbrancheamide (PubMed:31548667, PubMed:28777910).  MalA is also able to brominate premalbrancheamide at C-9 to yield malbrancheamide C, and, to a lesser extend, at C-8 to yield isomalbrancheamide C (PubMed:28777910).  Finally, malA can brominate C-9 monochlorinated malbrancheamide B at C-8 to yield malbrancheamide D, or C-8 monochlorinated isomalbrancheamide B at C-9 to produce isomalbrancheamide D (PubMed:28777910).
What are the official names of this protein?
Prenyltransferase malE, Malbrancheamide biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: FABA_HYDCU
Sequence: MEQQSSYNKEELLSCGRGELFGPGNAQLPLPPMLMFDRITHISEEGGAYGKGEIRAELDVKKDLWFFECHFNDDPVMPGCLGLDAMWQLIGFFLGWTGGPGRGRALGAGEVKFYGQVLPTAKKVEYVINMKRVIKRKLYMGIGDAHLYVDGREIYSADDLKVGLFTNTDNF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BBLD2_TOBAC
Sequence: MKRNISMSLQRLLIILMMISFLFTSLLVPSVSATNLNTISTCLINYKVSNFSVYPTRNHAGNRYYNLLDFSIQNLRFAASSKPKPTVIIVPESKEQLVSSVLCCRQGSYEIRVRCGGHSYEGTSYVSFDGSPFVVIDLMKLDDVSVDLDSETAWVQGGATLGQTYYAISRASDVHGFSAGSCPTVGVGGHISGGGFGFLSRKYGLAADNVVDALLVDAEGRLLDRKAMGEEVFWAIRGGGGGIWGIIYAWKIRLLKVPKTVTSFIVPRPGSKRYVSQLVHKWQLVAPKLDDDFYLSISMSSASKGNIPIEINAQFSGFYLGTKTEAISILNEAFPELGVVESDCKEMSWIESTLFFSELDNVANTSDVSRLKERYFENKSYFKAKSDHVKTPISVGGIMTALDVLEKEPNGHVIFDPYGAAMQRISEEAIAFPHRKGNLFRIQYLVVWKEKDNNNIAKSNGYIEWIREFYNTMAPHVSSSPRAAYVNYMDLDLGVMDDYLMLNTSITASADHAVERARVWGEKYFLNNYDRLVKAKTKIDPLNVFRHQQGIPPMFASMPEHTYSSK
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (By similarity).  Catalyzes a late oxidation step subsequent to the pyridine ring condensation reaction in the biosynthesis of alkaloids (By similarity).
What are the official names of this protein?
Berberine bridge enzyme-like D-2.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Vacuole.
Protein: RL17_BACC4
Sequence: MAYRKLGRTSAQRKAMLRDLATDLIINERIQTTETRAKELRSVVEKMITLGKRGDLHARRQAAAFIRNEVANAETGQDALQKLFADVAPRYAERQGGYTRIAKIGPRRGDAAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.