PharMolix/UniProtQA huggingface dataset:
Protein: PABP2_ARATH
Sequence: MAQVQLQGQTPNGSTAAVTSAPATSGGATATQFGNTSLYVGDLDFNVTDSQLFDAFGQMGTVVTVRVCRDLVTRRSLGYGYVNFTNPQDAARAIQELNYIPLYGKPIRVMYSHRDPSVRRSGAGNIFIKNLDESIDHKALHDTFSSFGNIVSCKVAVDSSGQSKGYGFVQYANEESAQKAIEKLNGMLLNDKQVYVGPFLRRQERDSTANKTKFTNVYVKNLAESTTDDDLKNAFGEYGKITSAVVMKDGEGKSKGFGFVNFENADDAARAVESLNGHKFDDKEWYVGRAQKKSERETELRVRYEQNLKEAADKFQSSNLYVKNLDPSISDEKLKEIFSPFGTVTSSKVMRDPNGTSKGSGFVAFATPEEATEAMSQLSGKMIESKPLYVAIAQRKEDRRVRLQAQFSQVRPVAMQPSVGPRMPVYPPGGPGIGQQMFYGQAPPAMIPPQPGYGYQQQLVPGMRPGGGPVPSFFMPMVQPQQQRPGGGRRPGGIQHSQQQNPMMQQQMHPRGRMFRYPQGRGGSGDVPPYDMGNNMPLTIGALASNLSNATPEQQRTMLGEVLYPLVEQVEAESAAKVTGMLLEMDQTEVLHLLESPEALKAKVAEAMDVLRSVAAGGATEQLASLNLS
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.  In the cytoplasm, affects both translation and mRNA decay.  Stimulates translation by interaction with translation initiation factor eIF4G, a subunit of the cap-binding complex eIF4F, bringing the 5'- and 3'-ends of the mRNA in proximity.  The formation of this circular mRNP structure appears to be critical for the synergistic effects of the cap and the poly(A) tail in facilitating translation initiation, recycling of ribosomes, and mRNA stability.  During infection with potyvirus TuMV, acts as a potential integral component of the viral replicase complex that could play an important role in the regulation of potyviral RNA-dependent RNA polymerase (RdRp).  Binds to uridylated mRNAs and determines the size of uridine extensions (PubMed:26972004).  Limits uridine extension by URT1, likely by binding to the oligo(A) tail and preventing URT1 access (PubMed:26972004).
What are the official names of this protein?
Polyadenylate-binding protein 2, PABP-2, Poly(A)-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In TuMV-infected plants, partially retargeted in cytoplasmic virus-induced vesicles and in the nucleolus.
Protein: Y3735_BREBN
Sequence: MAIKLINIGFGNIVNANRIISIVSPESAPIKRIIQEARDRNMLVDATYGRRTRAVIITDSDHVILSAVQPETVAQRLTTKDDESDE
What are the official names of this protein?
Putative regulatory protein BBR47_37350.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: RPIA_STRZT
Sequence: MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEEGLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALLMEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREKDGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGVQISTSKKGK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: CF206_RAT
Sequence: MPPTQAESVIKNIIREIGQECAAHGEITSETVVAFMVKAVVLDPSNGFNMDRTLVKTDVQKLVKLCVARLLDNKNPSLDTIKMQVYFDMNYTSREDFLEEHHRVLESRLGIVSREITDTRACAKEELENLYRKIVSYVLLRSGLGSPTDIKIVREATAALQSVFPQAELCTFLTLSKKDKERQLKELTMIVTGIRLFNRDCGKGGEGIDDLPAILLEAIPATTHHIDSQLQIAQEQAFRYTAIIEKVTNNPLMAKELQPYMLKEALYNVRQYEIFLQTVLSDIITCAEEVELMTKQLAAQLEQLKMTVKSKTAVPTSQVFPIFIALASLWTSFQDETVLISVLSNLTTNLELFLGTHDLLFPEKVMQGLLDGVIVKTDMTRIEEHLEEKVQLADFRVLEWLFPETTANFNKLLIQYRGFCGYTFAVTDGLLLPGNPTIGILKYKEKYYTFNSRDAAYSFAENPDHYINLIKEKAKKNAELIQLLELHQQFETLIPYSQMKDVDKHFIKPITKCENGTQTDTHILPPTIVRSYEWNEWELRRKAIQLANLRQKMTHSVQTDLSHMRRDNASQVYPLKEVGTQSKREGSTRVPRPQIFIAGLRGGQSKTTHGVKINLTRAVDET
What is the function of this protein?
Essential for sperm motility and is involved in the regulation of the beating frequency of motile cilia on the epithelial cells of the respiratory tract (By similarity).  Required for the establishment of radial spokes in sperm flagella (By similarity).
What are the official names of this protein?
Cilia- and flagella-associated protein 206.
What is the protein family that this protein belongs to?
Belongs to the CFAP206 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body.
Protein: MNTP_SALSV
Sequence: MHFTATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGLGILASKFVLEWNHWIAFVLLIFLGGRMIIEGIRGGSDEDETPLRRHSFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMIGRFIGPMLGKRAEILGGVVLIGIGVQILWTHFHG
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Probable manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PUR5_PROMA
Sequence: MDYKSAGVNVEAGRAFVNRIKASVESTSRPEVIGGIGGFGGFMRLPRGLEKPVLVSGTDGVGTKLELAQDYGSHYGVGIDLVAMCVNDVITSGAEPLFFLDYIATGKLTPEALTEVIEGIAEGCNQSKCSLLGGETAEMPGFYSDGRYDLAGFCVAVVEENKIINGSKIKVGDQIIGIKSNGFHSNGFSLIRKVVKLAGVNEKSCFGSRKVPLIDYLLKPTQLYVHLVQALLQANLPVKGMAHITGGGLPENLPRCLPDGLAASIDRNNWEEPSIYKWLRNEGDIPESDLWNTFNFGIGFCLVVSPDQSKDLIDMCSANGFVAWNIGQVEEQPKQMQSRIVGLPT
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_THEAB
Sequence: MGQKVHPRGFRLGITADWQATWFNEKNYKEYLLEDEEIRKVIKNKYAQAGISEIVIERPDSERVIAIIKSARPGIIIGKKGAEITELRQELEKRFNRRFIVNVEEIKNPEVDAQLVAENIASRIEKRASYKVVMKKAIFNAMKKGAKGIKIMVSGRLAGAEIARTEWYLKGRLPLQTIKSIIDYGTARAETKYGTIGIKVWIYKGDADI
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: JAL21_ARATH
Sequence: MVQKVEARGGEIGDVWDDGAYDGVRKVYVGQGEDGIAFVKFEYVNGSQEVVGDERGKKTLLGAEEFEVDPDDYIVYVEGYHEKVFGVTTKEIISTLTFKTYKGKTSPPFGIVSGTKFVLQGGKIVGFHGRSTDVLHSLGAYISSPATPKLRGKWIKVEQKGEGPGPRCSHDIAQVGNKIFSFGGELTPNQPIDKHLYVFDLETRTWSISPATGDVPNLSCLGVRMVSIGSSLYVFGGRDASRKYNGFYSFDTTKNEWKLLTPVEQGPTPRSFHSMTADENNVYVFGGVSATVRLKTLDAYNIVDHKWVQCSTPGGSCSVRGGAGLEVVQGKVWVVYGFNGCEVDDVHCYDPAQDKWTQVETFGEKPCARSVFASAVVGKHILVFGGEIAMDPKAHEGPGQLSGGTFALDTETLKWEKLDKLGEEEETPSIRGWSASTTGTIDGKKGLVMFGGKAQTNDRFGDLFFYGVDSA
What is the function of this protein?
Promotes simple nitriles, but not epithionitrile or thiocyanate formation.  Converts allylglucosinolate and benzylglucosinolate to their corresponding simple nitriles in the presence of myrosinase.
What are the official names of this protein?
Nitrile-specifier protein 2, AtNSP2, Jacalin-related lectin 21.
What is the protein family that this protein belongs to?
Belongs to the jacalin lectin family.
Protein: VPA3_BEFVB
Sequence: MEIDGRRFAHLDEGRKTGHNVKGGGKFRLLPMAQHQRELVVSGGHEKTNIN
What are the official names of this protein?
Protein alpha-3.
Protein: VNUA_SUHVK
Sequence: MNLFRPLSHRLSLPSTTTTRDHHHQQHHHHPPPPPSRTHFTTITTSGRWLQRQFPVLTTTVFFSLFLSFPPHPPRPPQDHHRPTPARDHRDPRDHLPPTRTRRDHQHRPPPTTTTTTIKDPQHPQDPLLLPTKTLQEEDPHLLRPTRDPPSAKTHHHQDPPGGGPPSTSSHHHHQDPPGGGPPSPPPRPSTSSSSSHQGPPSTRPPPPQRPPPRWPPPSPQKISETRAGSENTAQTLFSHSENKLFSHPMGEGGEGDRGTAGGGEGDRDDPPPPSPPPRPPPPLPPPPPPPPPPQPPPAGGSARRRRRGGGPPGRGGRRRGGKRRRAEGTEAAAADAEEEEDGDGDEDEDEDRAEGEGREDGGEGPRGAGGGAGESESESGRAEGAPRSAEQQVGVAGVLGLLVVRDGLHLDGPERAAGPAVAAADADDLHRVPVLAGAGPGARGPRGPVGLHGAPGGGADAGLEGGKVPEHGRRGARGGDGARGQHQRGGLGVGLQQRRGAEGAQLGRQALGAAELGEAPAAAGDEDGPQRGAEPPAVGRAVPEGGARVKVRVPEPERGALAGHVLAAVHGGEHALAVGARRQRDRGPGPGAGAHRVAHVVLAAEAQRLGPGVQAGEGGLHAGEAGRAHDGARVQHGRAELAAPGPAHGALGGRVQADADVDVVVPHGRAVRGPVLDGVQHDEPAPRRAEPRAEVLHGAGEAEVPRREQQHPLGVEAADVGAPGPVPGPGVRVRRAEAVGEGGEQRREAAAARVPGRARGALGGLGAELLVGQRVVEHHHAHVLGVGYLPHPGGAAAERGAAARGDVRQGGRVEGERRAPEFGEDLLVHEGAGHLGRAVGGEGRLGGPRRVGLAGRDAAEAAVGRGVLGHGPERAPEPVVLGGGGGGGQQRGSGVRSGPESEGAALAPGPPVLFVVAVAVAVPAEGRAGEPLVLLAVPGAAGPGRAALLLAPLGRWVRAGGGGAGVAGGAGEAGLGAGAGLGAGAGLGAGGAGGPGAGEAGGGARRRRRRRWDDEAGLLGPERGQAGRGLRGPGPRGGLGEPGRGHVGRGEEGRGVGPGGLAGAGPVHAVAHQRRHGAGDEGDRVRGLPPLGRAGPGDRVAEREQRGRHLLEAGGPEGGRGAGGRGQPERAGQQALEDAAAGQDAGVRQLAGHAAGLRGGEGGADAGAEGLDGRLPGAGVRGAARVGHVGVGPAEALQDEGLLGAIVAAAHGHGAHRVRQGPERVLGGHGVPDVRQRRGHAAGDEGAVAVGRVDPALAELVEALVGGLHPRVLQPGHGLAGGPAVDEAHEGLVLLPRVPHLRDEDGHGPGRGAVAGRGLADVVLVPEPLAGVPGAAVADAAVGRRVGAGPGLPERGEQRPVGRRGPVGHEREVVVGGAALPARGPGGLRGRGRGGRGGGGGGGGRGPRGRGGRRRRRWRPGAGEWGAGPDSFVFFSLGGGRGRGGRGGRGGRGRGGGRAPRGGGGGPGGGGRAGRGEVRVAAAAAGAAEAAAAAEGALSGAAPAGLSLRGRPAVPGEAESVLVLLGAAGDGLDGDGGGGVGVGVGVGGDGAPGAKRPRIEPPRGGGLVEQGLAVLVMVTTAVPSGGGGAAAAGRRDRPGGGGGWGSGPPPCRRCGHRCWLCWWRRGPRPRRRPGLTDRVPPRGGPSPRGCRGAGRAGGGGRGGCGGGRAPGAAGGPGLCRCECCRGRRPGPGAGPGPGPEDEVTVLGALMESPTGGPGGRGPGLVLLLVFVV
What are the official names of this protein?
Probable nuclear antigen.
Protein: TATA_BORA1
Sequence: MGSFSIWHWLIVLVIVALIFGTKKLRNIGSDLGGAVKGFKDGMQEANADKTEQVTQQQTTIDVQAKEKQNS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NUD1_YEAST
Sequence: MDMDTQEAELSSQLENLTINSPRKLRSNAHSNSGKVFKEYESNHDFQDSNFTSQVVEPAISDSVKKPPTMTVLNNYSTVHQKVPSGFSGTTATSHQEAQWKQYFPGIGSGGGTNFGGAVGTANKVPESDLIVSDLVKDLSGVLETNTFKRHLDMKNKTTTMQTHENHDTISISHSKDFFNAEKVSSSFSDDSDSGPAAEAHDVFDGILQKQKSNYLVGSYPSNSNNKNNNNNNNNNNNNSININNKDNARTKEEDEEDTSNSFEFSSSSSMSSSQTQSGRKSKVLKKPPLNTISPGQLGYQFNHTHGAWDPPLNQGLDVSSSHSLDNTSSNQSQFATMVPTGDNHTNGKAPSILDKKAYELTSTKPGDVGYRQKKIQEEENLANSDDTPLDTPKFNDLFTKNGTRAKVKGQMRTSRSISNSNLLEAHKKLKTFPAERVEDITSISEVNTSFNETEKQLISILTSKLSGSPSYDSDWEKILKVDLSRGKLKNMFGMQRLLPNVLVLNLSDNEMNTLEGIPSNVVQLFCSNNKITSAHCSLAGFHDLECLDLSYNLLNTSLKFLSLCHHLQEVNLSYNSIQSLEGIGSSRMKKLNLSNNEINGIIDFEQLILTNNSVVGGWLTVEVLDLSNNNIIGVRNINCLPRLKVLNLNGNPLVSIVESSKMENGTLRALSIKNTGGALSKLQNYKLDDQFTFPYQNLKILKLDGFAQLSKWQKWPATLQILEINGGLASSLPRFSSLKSTNLYSLTIANVRDFTHLPVDLSKELPFLQELHLPGNNLQNAHKLTKTLPRQSVKFLDLRNNPITTPRHDRASTSLHYRQLLQLAGLCQQQCPALATLWLDDTPAPTATNL
What is the function of this protein?
Involved in astral microtubule organization by binding SCP72 to the outer plaque in a cell-cycle dependent manner.  Required for the mitotic exit by facilitating the binding of TEMP1 to CDC15.  Also involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation.
What are the official names of this protein?
Protein NUD1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus envelope. Note=Localizes to the meiotic outer plaque of the SPB, at the end of the meiotic spindles.
Protein: Y1634_FRACC
Sequence: MTTPTLDLAIITGLSGAGRSTAAKCLEDLGWFVVDNLPPELLSTMAELGRRSGGAISRIAVVVDVRGRPFFSDLRAAIAALDARGMHPRMLFLEASDDALIRRFEHVRRPHPLQRDERVVDGIGRERILLAELRGEADLVLDTTDLNVHELRSKIDAAFGQPNANRLNATVVSFGYKYGLPLDADLVADCRFLPNPHWVEALRPFTGRDPQVRDYVLAQPGAQDFLDQYSALLRLVGEGYAREGKRYLTLAVGCTGGKHRSVAIAEQLGIRLAAGGVGVRVVHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Francci3_1634.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RS3A_PICTO
Sequence: MADRRKIGTKDKWKEKTWYTIVAPSFLGEREIALSPAADPSLMIGRKVEVPVSDFTGNFRKSSTMVIFRVKECTGKRCTTEFIGHKVSDDTIRRMVRRRKERIDIIMPSKTKDGYRLVIKIVLVSDSKLTANKRGEVRSKIIGFINERCGSMTLPELAQYIIGDNVYNDIVDTLKDVYPIKKIEIRKSEVLGRDGYVEEPGAQTQIEAQ
What are the official names of this protein?
30S ribosomal protein S3Ae, Ribosomal protein S1e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS1 family.
Protein: RUVB_SPHAL
Sequence: MTDLTTPIRTPEDADAALRPKTLAEFVGQAAARENLRIFIEAAKARGDALDHVLFFGPPGLGKTTLAQIVARELGVGFRSTSGPVIAKAGDLAALLTNLEDGDVLFIDEIHRLSPAVEEILYPAMEDRALDIMIGEGPSARSVRIDLPQFTLVGATTRQGLLTTPLRDRFGIPVRLNFYTHAELEQVIGRAARLLGLAIAPDGALEIAKRSRGTPRIAGRLLRRVRDFAAVAGHAIVDARAADAALNRLEVDALGLDAMDRRYLTMIADIYRGGPVGVETLAAGLSEPRDTIEDVIEPYLLQIGLIARTARGRTLNASAWKHLGLNPPAGSQDGLFDK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NUOH_CAMJ8
Sequence: MSDFAFFALEALIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVADMIKLFTKEDIIPSNSQKFIFAIAPLISAICAFVSLAAIPMLPEFTLFGRVIQPIVADINVALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVAIISYESVGALALIAIVMLVGSFSLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSGLRWGMFFIGEYASMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFPQLRPDQVMKMCYLILIPLAVLNLLITALAVLL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: REP12_SALTI
Sequence: MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTLSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPNDESKENPLQPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR
What is the function of this protein?
This protein is essential for plasmid replication; it is involved in copy control functions.  In vitro, binds to the DNA repeat units, BCDD'D'', EFG and HIJ (By similarity).
What are the official names of this protein?
RepFIB replication protein A.
What is the protein family that this protein belongs to?
Belongs to the initiator RepB protein family.
Protein: RIP1_SAMNI
Sequence: MKVVATILYLVVLAICGLGIHGAHPTHSAPPTVYPSVSFNLTEANSNEYRHFLQELRGKVILGSHRAFDLPVLNPESKVSDSDRFVLVRLTNPSRKKVTLAIDVVTFYVVAFAQNDRSYFFSGSSEVQRENLFVDTTQEDLNFKGDYTSLEHQVGFGRVYIPLGPKSLAQSISSLSTYKSSAGDNKRLARSLLVVIQMVSEAARFRYIQLRIQASITDAKEFTPDLLMLSMENKWSSMSSEIQQAQPGGAFAQVVKLLDQRNHPIDVTNFRRLFQLTSVAVLLHGCPTVTKMPAYIIKMPVFNGGEDEERCSVVEEVTRRIGGRDGFCAEVKNGDEKDGTPVQLSSCGEQSNQQWTFSTDGTIQSLGKCLTTSSSVMIYNCKVVPPESTKWVVSIDGTITNPRSGLVLTAPKAAEGTLVSLEKNVHAARQGWIVGNVEPLVTFIVGYEQMCLETNPGNNDVSLGDCSVKSASKVDQKWALYGDGTIRVNNDRSLCVTSEGKSSNEPIIILKCLGWANQRWVFNTDGTISNPDSKLVMHVDQNDVPLRKIILSHPSGTSNQQWIASTHPA
What is the function of this protein?
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA.  The B chain binds to cell receptors and probably facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (lectin activity).  Agglutination is inhibited by Neu5Ac(alpha2,6)lactose, and N-linked glycoproteins such as fetuin and orosomucoid.
What are the official names of this protein?
Ribosome-inactivating protein SNAI'.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: S35B3_CAEBR
Sequence: MTVAQIHSDCSSSMLPRHIKDDVEPIHLLGFNIARKPKWLQFVLLSGAIFILYLGYGYMQELIFKLPGMKPFGWTLTLIQFVIYSGCGYAECAVWHNTKRMIPWRIYGVIAFFTVATMGLSNASVGYLNYPTQVIFKCCKLIPVLIGGILIQGKRYGWIDISAAILMSLGIIMFTLADNKVSPNFDSRGYIMISGALLADAVIGNIQEKNMKKYGGSSNEVVLYSYGIGSVFIFTYVVLSGEIFSAIPFFLENSWKTFGYALIFSFLGYLGVNVVLTHIKVFGALVAVTVTTLRKALTIILSFLLFSKPFTIEYVYAGSVVMLAIYLNLYSKNKASWDHMIRIFVARAMGYHAVATKKDPMMV
What is the function of this protein?
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi.  PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi (By similarity).
What are the official names of this protein?
Adenosine 3'-phospho 5'-phosphosulfate transporter 2, Adenosine 3'-phosphate 5'-phosphosulfate transporter, PAPS transporter 2, Solute carrier family 35 member B3 homolog.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: EGR1A_XENLA
Sequence: MAVAKTEMLVSPLQISDPFSSFPHSPTMDNYPKLEEMMLLNAGGPQFLGASVPDGSGFNSTVEGAEQFDHLTADAFSEMSLSSEKALVESSYANQTTRLPSLTYTGRFSLEPATNSSNTLWPEPLFSLVSGLVGMANISPSSAPSSSPSSSSSSSSSQSPPLSCSVQSNDSSPIYSAAPTFPNSSSEIFPDHSPQPFQNASIPYPPPAYPVSKTTFQVPMIPDYLFPQQQGDVSLVSADQKPFQAMESRTQQPSLTPLSTIKAYATHTSQDLKTINSTYQSQIIKPSRMRKYPNRPSKTPPHERPYGCPVESCDRRFSRSDELTRHIRIHTGQKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDICGRKFARSDERKRHTKIHLRQKDKKADKATPVSVASPVSSYSPSASTSYPSPVPTSYSSPVSSSYPSPVHSSFPSPTTAVTYPSVTSTFQTHGITSFPSSIMTNAFSSPMSSALSDMSLTYSPRTIEIC
What is the function of this protein?
Transcriptional regulator.  Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity).  Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity).  Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia.  Plays a role in the regulation of cell survival, proliferation and cell death.  Mediates responses to ischemia and hypoxia; regulates the expression of proteins that are involved in inflammatory processes (By similarity).  Plays a role in regulating the expression of circadian clock genes (By similarity).
What are the official names of this protein?
Early growth response protein 1-A, EGR-1-A, Xegr-1.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: DNLJ_BURTA
Sequence: MARSPVEPSAGQPAKRAAWLRAELERANYAYYVLDQPDLPDAEYDRLFAELQQIEAEHPDLVTPDSPTQRVGGEVASGFTPVVHDTPMLSLNNGFSDDDVVAFDKRVADGLDKPTDLAGTVTEPVEYACELKFDGLAISLRYENGRFVQASTRGDGTTGEDVTENIRTVRSIPLTLKGKRVPRMLDVRGEVLMFRRDFARLNERQRAAGQREFANPRNAAAGSLRQLDSKITASRPLSFFAYGIGVLDGVEMPDTHSSLLDWYETLGLPVNRERAVVRGAAGLLEFFHSVGARRESLPYDIDGVVYKVNRRDEQDRLGFVSRAPRFALAHKFPAQEALTKLVAIDVQVGRTGAITPVARLEPVFVGGATVTNATLHNEDEVRRKDIRIGDTVIVRRAGDVIPEVVSAVFDRRPADAREFVMPTECPECGSRVERLPDEAIARCTGGLFCPAQRKQALWHFAQRRALDIDGLGEKIIDQLVEQNLVRTPADLFNLGFSTLVELDRFAEKSAQNLIDSLEKAKHTTLARFIYALGIRHVGESTAKDLAKHFGSLDPIMDASIDELLEVNDVGPIVAESIHQFFAEAHNRTVIEQLRAKGKVTWPEGPPAPRAPQGVLAGKTVVLTGTLPTLTREAAKEMLEAAGAKVAGSVSKKTDYVVAGADAGSKLAKAEELGIPVLDEAGMHKLLEGHAR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: Y5844_DICDI
Sequence: MNNRGGFSHPPGKFHMRGSKTYTPRNGGQGQGQPQQAAPAFDQQQQQQQQQQQQQQQQQQNFDQQQQQPQQPQQQQGGNNYYFQSKFGNKSHRGGYHGNGNGNNNGNNNNNNTSPNLNSTSHNNNNNNNNNNNNNNNNNNNTHFTNSRGGHRGGSSRGGSSRGGNSGSSRGGSRGGYRGQSSFYNSSYQKSGPRLLTSIVSLPPFSGGAIIGVKGSLWGLLNKATTARLKVFKNTAIIKCADAQQLDRAKEIVLKLKNTSPKYLSLIDYKGEQKIKFVHQPSFSEVILESGAIDPLATDGVQLMQDLINSHESQYVARLNETFSTLYSEKGSSTPFIDIEAGKIWYLHSSNIPSTPMTADKYELYTESLASVFQPSNVINEQFITSSQYKLFKQKKQFTFISVLDTESLDLLCIKCSEEKITPTTTTTTNTQQSPNSDSSEYKFTDPFIYKLNHINSSKVLFPQIKSGSDLRVTIDTHSKSKLVSGTGQHQYDNLIKFIDSIKIHKNSSGNNTYQIPDSNLFMTESIITRKVLMYRSDDNSLQFHVNEDIATRYTTSTPEVNRESTTVFCTSPALYDLFKSKNWTVDQASDELKKLSKNLRLLVSKHLDSTKFQPPSADHTTQFEQDDEEEEN
What are the official names of this protein?
Putative uncharacterized protein DDB_G0284097.
Protein: REX_ROSCS
Sequence: MDRMEGPPDVVVRRLPLYARSLRYLLQEGVESVSSQELGDRINVTAAQIRKDLSYFGEFGKQGIGYDVRRLLQQIEDILGLTQEWPVALIGIGHLGEAIARYEGFRQQGIRIAGLFDSNPTKIGKAINGMTVQSFDDAERVIREQGIRLAIIAVPARNAQEVADRLVMAGVRAILSYAPTVLQVPEGVWVRYIDPVAILHSMTYYLARDIAGVRHNNPET
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDFT_CANGA
Sequence: MGKVLDLALHPLELRAALKLKFIRQPLFSTNDTRATPQLERCYELLNLTSRSFAAVIMELHPELRNVIMVFYLILRALDTVEDDMTIDPQLKVKVLREFDSKLDTTDWSFDGNDLKEKDRVVLTEFPCILGEYHKLKPEYQKVIKRITGLMGNGMADYILDENFNLNGVQTVKDYDKYCHYVAGLVGDGLTELIVLAGFGSDDLYHGKNSFQLYESMGLFLQKTNIIRDYAEDLDDGRSFWPKEIWSEYATKLTDFRDPKNTQKGVDCINHLVLNALTHVIDVLTYLSSIHEQSSFQFCAIPQVMAIATLAKVFNNPEVLRKNVKIRKGTTCDLILNSRTLKGCVDIFQYYLRDMKQRLPVEDPNYLKFNIQVAKIEQFIEEMFQDNLPAGVEPRETMIYLKVQERLKWDTQVIPRVQEEDYKFNMALSVVFCVLLSFYFFTK
What is the function of this protein?
Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene.  It is the first committed enzyme of the sterol biosynthesis pathway.  Required for the biosynthesis of ergosterol.
What are the official names of this protein?
Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS16_THEMA
Sequence: MVRIRLTRMGKRHQPFYRIVVVDSRKRRDGAYIESLGYYNPLKEGEIKIDVERAVEWILKGAQPSDTVRDIFRKFGVMKRVHEIKYGKKEEATAE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.