PharMolix/UniProtQA huggingface dataset:
Protein: RIR2_RSIV
Sequence: MDRYVLRPNDPHLWAMYKKAVASFWTVEEVDLSTDVRHWTDKLTEAERRFMSHILAFFAMADGIVGDNLVCNFAKELDHIPEARAFYGFQVAIENIHAEMYTQLIITLVAKENQAALFSAAEDMPCVKAKAQWAAQWLNATHKPIATRLLAFAAVEGVMFSGSFAAIFWLKKRSLMPGLAFSNELISRDEGLHCDFACMLFRQMANKPCQDDAHQIISDAVDIETAFFREALKTPLLGMNSDSMKLYIQFVADRLLDALGYAKMYNVSNPFDFMDNISIEGKTNFFERRVSEYQRMGVFTPSSMEFTMNEEF
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: RHBL2_TOXGO
Sequence: MANIRTLSDYASSPPRGSSALEGEVGQGGSPLPLFFPSGTQSGENVSWIQWLCPGIHLKSPIIIISFVQIAVYIASLAAGLAPNEILAPTPQTLVMFGANIPELIRVGEIWRLICPLFLHLNLFHILMNLWVQIRIGLTMEEKYGWKMLLAVYFGVGVLANMISAAVLFCGQMKAGASTAVFALIGVQLAELALIWHAIQDRNSAIISVCICLFFVFVSSFGSHMDSVGHIGGLVMGFAAGIWLNENSDIKPTWYDRARLTSQVALAAAPILSCIFIFLVPRC
What is the function of this protein?
Serine protease involved in intramembrane proteolysis and the subsequent release of polypeptides from their membrane anchors.
What are the official names of this protein?
Rhomboid-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RK1_PHATC
Sequence: MQKVSRRHKENFERTKNIVYSNIDEAIAVLKETATTKFVESVELHANLNIDPKYADQQLRTTVTLPNGIGKQVVIAVLTNEENFEEAKSSGGDIVGNDELIAQITQGQINFDLLIATPNMMPKLAKLGRMLGPKGLMPSPKSGTVTSTLQSTLTEFKKGKFEYKADKTGIVHVNFGKSNFTNEQLVENLKALYQSIEQNRPSGVKGKYFKSVSICTTMGPSVKLDLEIFA
What is the function of this protein?
Binds directly to 23S rRNA.  Might be involved in E site tRNA release (Potential).
What are the official names of this protein?
50S ribosomal protein L1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TDH_VIBC3
Sequence: MKIKALSKLKPEQGIWMNEVDMPELGHNDLLIKIKKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVRGFQIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRTGCFSEYLVIPAFNAFKIPDGISDDLASIFDPFGNAVHTALSFDLVGEDVLITGAGPIGIMAAAVAKHVGARHVVITDVNEYRLDLARKMGVTRAVNVAEQNLEDVMKELGMTEGFDVGLEMSGVPSAFSAMLKTMNHGGRIALLGIPPSSMAIDWNQVIFKGLVIKGIYGREMFETWYKMASLIQSGLDISPIITHHFKVDDFQKGFDIMRSGASGKVILDWQ
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2D3_HAEIN
Sequence: MKKSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPEAIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQRGNAGDVIALSKEFNYGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTTKSQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKKTSVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEYWKKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-AAGCTT-3' and cleaves after A-1.
What are the official names of this protein?
Type II restriction enzyme HindIII, R.HindIII, Endonuclease HindIII, Type-2 restriction enzyme HindIII.
Protein: PLCH1_MOUSE
Sequence: MADLEVYKNLSPEKVERCMSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSEKAKILIDSIYKVTEGRQSEIFHRQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWITGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNLPRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEELAQFLKVEQKMSNVTLDYCLDIIMKFEVSEENKVKNVLGIEGFTNFMRSPACDVFNPLHHEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPDGEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKGILQDKLDLSSVDTGECRQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEIEDECKFKLHYSNGTTEHQVESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHEGLNAHLKQNLDVKESGKKSHGRSLMANFGKHKQKATKSRSKSYSTDDEDDSLQNPGKEGGQLYRLGRRRRTMKLCRELSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSEQFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQINRAKFKANGNCGYILKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEIIDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDPIGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIFGKWSPLILNPSYTILHFLGATKNRQLQGLKGLFNKNPRHASSENNSHYVRKRSIGDRILRRTASAPAKGRKKSKVGFQEMVEIKDSVSEASRDQDGVLRRTTRSLQVRPVSMPVDKSLLGALSLPISEAAKDTDGKENCLAGDKDDRRKGAATRKDPHFSNFNKKLSSSSSALLHKDANQGPTASVSNPEQCGGRGAKSERIKPNMTNDCQENHNPPKFLSPRKHLALDPATKGLQERLHGMKTNEKEHAEGFLGEKSMLSGSVLSQSSLEVENLEGSRAKGRAATSFSLSDVSALCSDIPDLHSTAILQDTEISNLIDDVTLTNENQSGSSISALIGQFEESNHPANVTVVSHLSTSGASGSAPFQTPFKHGLSQGNQKASFLCSSPELNKLSSVETTKLANNAVPCGVIGSPISTPKPGDDPSDKAKTRVIEGNLPGFPDASPGQFPKSPTHGEDHSQVMNSPALSTELAIEDIIADPALSINSAESSLVEIDGESENLSLTTCDYREEAPSQLVSPLKLQQSQEMVEHIQRGLRNGYCKETLLPSEIFNNIPGVKNHSISHLTYQGAGFVYNHFSSSDAKTNQICEPQQPRAPDMHAPTPTPSTHAPLAALKLPSPCKSKSLGDLTSEDIACNFESKYQCISRSFVTNGIRDKSVTMKTKSLEPLDALTEQLRKLVSFDQEDSCQVLYSKQDVNQCPRALVRKLSSRSQSRVRNIASRAKEKQEAGKQKAMAQSTRGGVVLRSKPPAPALAVNRHSTGSYIASYLRNMKAGGLEGRGIPEGACTALRYGYMDQFCSDNSVLQTEPSSEDKPEIYFLLRL
What is the function of this protein?
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes.
What are the official names of this protein?
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1, Phosphoinositide phospholipase C-eta-1, Phospholipase C-eta-1, PLC-eta-1, Phospholipase C-like protein 3, PLC-L3.
What are the subcellular locations of this protein?
Cytoplasm. Membrane.
Protein: NDHI_PARMW
Sequence: MFGFLKQVGDYTRDAVDAARNLAQGFSVTFDHMKRRPVTVQYPYEKLIPSERYRGRIHYEFDKCIACEVCVRVCPINLPVVDWVMNKATKKKELRNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELAAFDRHSLNYDNVALGRLPTSVTTDPSVQPLRELAYLPAGEMDPHGVPNDRPRAGQLPSQVLETLAPPAKVGAKNEGQSTGTTQEGEA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, NAD(P)H dehydrogenase I subunit I, NDH-1 subunit I, NDH-I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: METN2_BURCH
Sequence: MTQLFDTLGFIEASAVRAGAGADAVAHEEAVTPVGGAAVSLEQVGKVFATPRGQAAALRDVTLDVRRGEVFGIIGRSGAGKSTLLRLLNGLERPSSGRVRVQGVDVGALDEDGLVALRRRTGMVFQHFNLLSAKTVFENVALPLKIAGVPKAERVRKVEALLELVGLAAKRDAYPASLSGGQKQRVGIARALVHDPEVLLCDEATSALDPETTQSILALLADINRRLGLTIVLITHEMEVIRAVCDTVAVIEQGEVVETGPVWRVFGDPRHGATRALLSTLQHDLPAELAARVRPLPEQAALPDGAQIVLDVRYTGESGGEPDVGALAAALGGSVRFLHGGIESIQGHAQGRLVIAATPRADDAGPSTARGGAVAALLERARRHANHAEVLGYV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CYB_ECHKA
Sequence: MTNLRKTHPLMKIVNDAFIDLPAPSNISAWWNFGSLLGICLVIQILTGLFLAMHYTSDTLTAFSSVAHICRDVNYGWLIRNLHANGASMFFMCLFLHVGRGIYYGSYLFKETWNIGVILLLTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVIVHLLFLHETGSNNPSGLNPDSDKIPFHPYYTIKDALGLLMMILILLLLAMFTPDMLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLLIIPLLHTSKQRSLMFRPISQTLFWLLTADLFILTWIGGQPVEQPFIIIGPVASIMYFLIILALMPLAGLIENYMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IDE_RAT
Sequence: MRNGLVWLLHPALPSTLHSILGARPPPVKRLCGFPKQIYSTMNNPAIQRIEDHIVKSPEDKREYRGLELANGIKVLLISDPTTDKSSAALDVHIGSLSDPPNIPGLSHFCEHMLFLGTKKYPKENEYSQFLSEHAGSSNAFTSGEHTNYYFDVSHEHLEGALDRFAQFFLCPLFDASCKDREVNAVDSEHEKNVMNDAWRLFQLEKATGNPKHPFSKFGTGNKYTLETRPNQEGIDVREELLKFHSTYYSSNLMAICVLGRESLDDLTNLVVKLFSEVENKNVPLPEFPEHPFQEEHLKQLYKIVPIKDIRNLYVTFPIPDLQQYYKSNPGHYLGHLIGHEGPGSLLSELKSKGWVNTLVGGQKEGARGFMFFIINVDLTEEGLLHVEDIILHMFQYIQKLRAEGPQEWVFQECKDLNAVAFRFKDKERPRGYTSKIAGKLHYYPLNGVLTAEYLLEEFRPDLIDMVLDKLRPENVRVAIVSKSFEGKTDRTEQWYGTQYKQEAIPEDVIQKWQNADLNGKFKLPTKNEFIPTNFEILALEKDATPYPALIKDTAMSKLWFKQDDKFFLPKACLNFEFFSPFAYVDPLHCNMAYLYLELLKDSLNEYAYAAELAGLSYDLQNTIYGMYLSVKGYNDKQPILLKKITEKMATFEIDKKRFEIIKEAYMRSLNNFRAEQPHQHAMYYLRLLMTEVAWTKDELKEALDDVTLPRLKAFIPQLLSRLHIEALLHGNITKQAALGVMQMVEDTLIEHAHTKPLLPSQLVRYREVQLPDRGWFVYQRRNEVHNNCGIEIYYQTDMQSTSENMFLELFCQIISEPCFNTLRTKEQLGYIVFSGPRRANGIQGLRFIIQSEKPPHYLESRVEAFLITMEKAIEDMTEEAFQKHIQALAIRRLDKPKKLSAECAKYWGEIISQQYNYDRDNIEVAYLKTLSKDDIIKFYKEMLAVDAPRRHKVSVHVLAREMDSCPVVGEFPSQNDINLSEAPPLPQPEVIHNMTEFKRGLPLFPLVKPHINFMAAKL
What is the function of this protein?
Plays a role in the cellular breakdown of insulin, APP peptides, IAPP peptides, natriuretic peptides, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling (PubMed:1836994, PubMed:1445854, PubMed:10684867, PubMed:12941771, PubMed:14527953, PubMed:22049080).  Substrate binding induces important conformation changes, making it possible to bind and degrade larger substrates, such as insulin (By similarity).  Contributes to the regulation of peptide hormone signaling cascades and regulation of blood glucose homeostasis via its role in the degradation of insulin, glucagon and IAPP (By similarity).  Plays a role in the degradation and clearance of APP-derived amyloidogenic peptides that are secreted by neurons and microglia (PubMed:10684867).  Degrades the natriuretic peptides ANP, BNP and CNP, inactivating their ability to raise intracellular cGMP (By similarity).  Also degrades an aberrant frameshifted 40-residue form of NPPA (fsNPPA) which is associated with familial atrial fibrillation in heterozygous patients (By similarity).  Involved in antigen processing.  Produces both the N terminus and the C terminus of MAGEA3-derived antigenic peptide (EVDPIGHLY) that is presented to cytotoxic T lymphocytes by MHC class I.
What are the official names of this protein?
Insulin-degrading enzyme, Insulin protease, Insulinase, Insulysin.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Secreted.
Protein: Y544_METTH
Sequence: MVEEHRDVIYVTSNYVPGYRAVEVLGFVYGLTVRSRRLGGQIDRFKSILGGEIKEYVTMMEHSRQEALERMLDHARELGANAVISVRFDSDSISDIMQEILAYGTAVIVEPEE
What are the official names of this protein?
UPF0145 protein MTH_544.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RIMP_BRADU
Sequence: MTEPTVGSTDAELLAEPRLVVEPGVAARVSAVAGPVLQGMGYRLVRIRISGEAGCTVQIMAERPDGSMQIEDCEAISRALSPVLDVADPIDRAYRLEISSPGIDRPLVRRSDFERYAGHLVKVEMAVAHEGRKRFRGMIGAVEGDRVHLQRDDVKAGEERNVLLTMEDISEARLVLTDELIAESMRRGKAAAREMRRNLGLEPPAAPHAKISEKTTKNTKPKKKPAPTNTKKHRLAAERARRGEIEPDEGD
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POK_DROME
Sequence: MSKMKMLPVQLSLNSLNPGIWSDVLWRCPPAPSSQLAELKTQLPPSLPSDPRLWSREDVLVFLRFCVREFDLPKLDFDLFQMNGKALCLLTRADFGHRCPGAGDVLHNVLQMLIIESHMMQWHLPNSPVTPTSRYPLSPHSHPPTPTWPPLNAPPENSPFHSSAHSLAGHHFMAPNSVTLSPPPSVDSQASSPPQAPYQNGGATGAAPGSAGGSAPAAGGATNTSNPTSSSASSTGSNGSQPNIMPMKGISSASSNHSDSEEEYSETSGGVSKMPPAPLSYSTASPPGTPILKDIKPNWTQQLTNSFVNSWSQQQQQQQQQQAAAVAAVAAQAQQHQLQQQQQQQQLPQKLTLDNTAGPVVTPAGGSISAPTTPSYMYKAKREFFPENSEPNTNGRLLWDFLQQLLNDRNQKYSDLIAWKCRDTGVFKIVDPAGLAKLWGIQKNHLSMNYDKMSRALRYYYRVNILRKVQGERHCYQFLRNPTELKNIKNISLLRQSTPANGNGGSPSMPQGSSQAPGSPAGQNWNPQQQSQQQQQSPQRPASRNGPMSLPAVAAVAAAAAAAYGPPPTSPLFMHAINGAFHYLSAAAAGPPPNSPALNTPSAVGGPDKFQFHPLKLENGSGSGSESAGEDLKPTDLSVSSKSTATSNEDCYPLIRNADGLTTIKLIRYNEHQVAASPAGQSPKHDDQQAGASNASSSPRPMDQASEQAQPVPMESDCNGGESEDSFRHMQQ
What is the function of this protein?
Ets-related protein that functions as a negative regulator of photoreceptor development acting antagonistically to pnt and the proneural signal mediated by RAS (PubMed:1505027, PubMed:1495974, PubMed:8033205).  It acts upstream of SINA to inhibit R7 development (PubMed:1505027, PubMed:1495974).
What are the official names of this protein?
Ets DNA-binding protein pokkuri, Protein anterior open, Protein yan.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus. Note=In undifferentiated cells during the early stages of eye development.
Protein: LYSY_PYRAB
Sequence: MIKAAIVGGSGYIGGELIRLLSMHPEVEITTITSRKFAGKKVHKVHPNLRGLNLRFTDKYEFDADVIFLAVPHGTSMRIIGEFLGSAKIIDLSADFRVSKDLYEKYYGSHEKPELIDKFVYGLPELHRKEIKRAELVANPGCNATAVILALYPFRDVTSEAIVDLKVSSSAGGRRENVASIHPERSHVVRVYKPFHHRHEAEVLQETGVKAMFTVHSVDIVRGLLATTYFKFEGSEKDLLKRLLMYRGEPFIRLVTDKGGLQRYPDPKYVIGSNFVDIGFSYDSENSRAIVFSALDNLIKGGAGQAVQNMNIMFGFDETLGLNYYPLYPG
What is the function of this protein?
Involved in both the arginine and lysine biosynthetic pathways.
What are the official names of this protein?
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEPO_LACHE
Sequence: MRRYLAVRGGAGDVAEPDLNAKPQDNLYLAVNSEWLSKAEIPADQTSAGVNTELDIKIEKRMMKDFADIASGKEKMPDIRDFDKAIALYKIAKNFDKRDAEKANPIQNDLQKILDLINFDKFKDNATELFMGPYALPFVFDVDADMKNTDFNVLHFGGPSTFLPDTTTYKTPEAKKLLDILEKQSINLLEMAGIGKEEARVYVQNALAFDQKLSKVVKSTEEWSDYAAIYNPVSLTEFLAKFKSFDMADFLKTILPEKVERVIVMEPRFLDHADELINPANFDEIKGWMLVKYINSVAKYLSQDFRAAAFPFNQAISGTPELPSQIKQAYRLANGAFDEAVGIFYGKKYFGEEAKHDVEDMIHNMLKVYEQRINDNNWLSEDTKKKAIIKLRALVLKIGYPEKIEKIYDLLQIDPERSLYENEAQMATVRTKYMLDKLTQPVDRSVWLMPGNLNNACYDPQRNDLTFPAGILQAPFYDIHQSRGANYGGIGATIGHEVSHAFDNSGAKFDEHGNMNNWWTDEDFAEFNKRVGQMVDIFDGLQYGPAKINGKQVVGENIADLAGLACAVQAGKNDNVDLKDLFENYARSWMQKQRPEAIKTEVQVDVHAPQPTRVNIPVQCQDDFYTAFDVKPDDGMWLDPEDRITIW
What are the official names of this protein?
Neutral endopeptidase, Endopeptidase O.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
Protein: YCCT_SALDC
Sequence: MKTGALTTFLALCLPVTVFATTLRLSNEVDLLVLDGKKVSSSLLRGAESIELENGPHQLVFRVEKTIRLSGNEERLYISPPLVISFDTQLISQVNFQLPRLENEREASHFNAAPRLALLDGDAMPIPVKLDILAITSTAKVVDYEIETERYNKSAKRASLPQFATMMADDSTLLSDVSELDTVPPQSQTLTEQRLKYWFRLADPQTRHHFLQWAEKQPPS
What are the official names of this protein?
UPF0319 protein YccT.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: LPHI_ECO57
Sequence: MTRVQFKQHHHHHHPD
What is the function of this protein?
This protein is involved in the attenuation mechanism for the control of the expression of the his operon structural genes.
What are the official names of this protein?
his operon leader peptide, his operon attenuator peptide.
What is the protein family that this protein belongs to?
Belongs to the HisL family.
Protein: NP10_HUMAN
Sequence: MNPSEMQRKGPPRRWCLQVYPTAPKRQRPSRTGHDDDGGFVEKKRGKCGEKQERSNCYCVCVERSRHRRLHFVMC
What is the function of this protein?
May possess a function in tumorigenesis.
What are the official names of this protein?
Endogenous retrovirus group K member 10 Np9 protein, HERV-K10 Np9 protein, HERV-K107 Np9 protein, HERV-K_5q33.3 provirus Np9 protein.
What are the subcellular locations of this protein?
Nucleus. Note=When overexpressed.
Protein: VPS10_MAGO7
Sequence: MRLGAALQAAALLTASLWSHPLLAASDDPAFKTTKLDHYPFNLNYFEDSDIVLYQDEARGTISRSEDAGATWTLVKDIEEGKAFQLVMHPFDRKRAYVLTSPGIHHFRTHDQGRTWQDFLADTEMTMFRLDILSFHATDPDRIIFNGMDCKEGKFFCEEVAMYTTDGFTSDAKFLRGSTSGCSWAKSSKLFTTGQDDLDKNRILCVVRDHFSPLKQDQRLMISDNFFSAKDAGGVIQEFEPNLDMTRPIQGVVNVAVVKKYLLVAASSMNTDEMSLFVSDDTLKWHRAMFPTDHKINQESYTVLESTEYSIQVDVMTTHPSNPMGVMYTSNSNGTFFTRNIEHTNRNHRGHVDFEKITGVQGIFMVNKVDNAEEVEKDRRGKKKIVSEITFDDGRTFEPIHADKERLHLHSVTELINAGRVFSSPAPGLVMGNGNTGKHLESWKDASLYISDDAGLTWIKGPNGPHKYEFGDQGSVLLAVMQAEEVDEVKYSLNHGKDWKTAKLPDDLKVKPIILTTTQDSTSLKFILIGEGKGRDEFHIVAIDFSSMHEATCKDSDMEDWYARVDDKGKATCLMGHTQKYRRRKKDADCFVKQEFKDPVPETKDCECSDQDFECDYNFKRDGKECVLVGTVVAPDGACKNAGPDDTFKGSSGWRLIPGNTCKRASGAQKDDLVDRKCKETSEPTPSEPSGNISTTPHNFSGDWLDFEKHYLEKGAESMDENEVVIARPINAQNAGQIFLTKDHGKTWHMPEALKDKNIWGIVTHQYFKEMAFFVQDTGSVIYTVDHGEHFHDFKAPGNGIDPDTKPLVFHPDHKDWMIWIGKKCEENTCYREASFSQDRGDNWKSIARYVYKCEFTGSSSYKFRSQDQIICSIQSREGNEKNIPFDLVSSNDLFKTSEVRQKNIKDFATMAEFIVVAAEDPERKSLKAFASLDGDSYAATRFPSNLDVKEERAFTILDSSTHAVKLFVPSPAQKDRCVGSIAKSNSNGTDYVVSITGVNCDENYFVDFEKMLTLEGVILVNIVANRENTNEPKKRRSLISHSDGATWSYLPPPRVDAEGKNYPCTSSDNGDENCALHIHGYTERKDHGKTYSSAGAVGLMFGVGNVGSTLGDIKDADTFLTTDAGISWKSVKKGAWRWAYGDQGSILMLVPSTKTKMVSYTTDEGETWNDHNFTDEPVDVLDMTTVSSGGSRNFLLWCRRSDKTVFAVNLDLTGLANTACKQVDDNDSESDYYAWSPSHPLRPDDCLFGHKSYYLRKKTDRKCYNKHKITPVFKMDVCECTREDFECDYNYELEGVGRNCVLAKGAQPMSREDWCSAHPKESTWYEPSGFRRIPISTCKEGRVFDNYTTSWPCPGHEEEYERQHGGPGGFTIFLIVILCVGAAGAVGVWVHRRWESGGFGQIRLGEQSSSGISFLDPDSPWVRYPVVAVSATVALVGALPLLVGALWRTTKTTVERWGIFGGVGRGTYGSLGLGGGSGARRFTTRDSFARGRSDYAGIDEDEGELLGDDSDEEV
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: STAG3_RAT
Sequence: MPTLWSPSTQHHGSSSGSMSSPLRKSVRCAQMALSPCSSNIQPCDDRDSQGTAEWDSSSTSEDSDFEDSLRRNVRKRAAKRPPKAIPVAKHPKKQSHIVPGGNDKNKSVPPTSDLFDAVKAARSCAQSLVDEWLENYKQDENAGFLELVNFFIRACGCKSTVTPEMFKTMSNSEIIQHLTEEFNEDSGDYPLTAPGPSWKKFQGSFCEFVKTLVCQCQYSLLFDGFPMDDLISLLIGLSDSQVRAFRHTSTLAAMKLMTSLVKVALQLSLHKDNNQRQYEAERNKGPEQRAPERLESLLEKRKEFQENQEEIEGMMNAIFRGVFVHRYRDILPEIRAVCIEEIGCWMQSYSTSFLNDSYLKYIGWTLHDKHKEVRLKCVKALAGLYSNQELSSRMELFTNRFKDRMVSMVMDRESEVAVEAIRLLTLILKNMEGVLTSADCEKIYSIVYISNRAMASSAGEFVYWKIFHPECGAKAVSGRERRRSPQAQRTFIYLLLAFFMESEHHDHAAYLVDSLWDCAGSYLKDWESLTSLLLQKDQNLGDMQERMLIEILVSSARQAAEGHPPVGRITGKKSLTAKERKLQAYDKVKLAEHLIPLLPQLLAKFSADAENVAPLLRLLSYFDLNIYCTQRLEKHLELLLQQLQEVVVKHVEPEVLEAAAHALYLLCKPEFTFFSRVDFARSQLVDLLTDRFQQELDDLMQSSFLDEDEVYSLTATLKRLSAFYNAHDLTRWEISEPCSRLLRKAVDTGEVPHQVILPALTLVYFSILWTVTHISESTSQKQLMSLKKRMVAFCELCQSCLSDVDPEIQEQAFVLLSDLLLIFSPQMVVGGRDFLRPLVFFPEATLQSELASFLMDHVFLQPGELGNGQSQEDHVQIELLHQRRRLLAGFCKLLLYGVLELDAASDVFKHYNKFYEDYGDIIKETLTRARQIDRCQCSRILLLSLKQLYTELIQEQGPQDLTELPAFIEMRDLARRFALSFGPQQLHNRDLVVMLHKEGIKFSLSELPPAGSSREPPNIAFLELLSEFSPRLFHQDKQLLLSYLEKCLQRVSMAPSHPWGPVTTYCHSLHLVENTAEASSQGPPHSKKRCIEVPRRLQEEESSSQGESLQLNSGPTTPTLTSTAVKRRQSPRTVGKRQKGGPGPGPGPGPGPGPGPGPGPGPGPGPELICSQQLSGTQRLKMSSAPCFQIRCDPSGSGLGKQMTRLSLMEEDEEEELRLLDEEWQCGDKLLHSPSSPSEHGLDLLDTTELNMEDF
What is the function of this protein?
Meiosis specific component of cohesin complex.  The cohesin complex is required for the cohesion of sister chromatids after DNA replication.  The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped.  At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.  The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.
What are the official names of this protein?
Cohesin subunit SA-3, SCC3 homolog 3, Stromal antigen 3, Stromalin-3.
What is the protein family that this protein belongs to?
Belongs to the SCC3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin. In prophase I stage of meiosis, it is found along the axial elements of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. It however remains chromatin associated at the centromeres up to metaphase I. During anaphase I, it probably dissociates from centromeres, allowing chromosomes segregation (By similarity).
Protein: GAL7_ECOLI
Sequence: MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQVLPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESHDPLMRCQSARGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGCSNPHPHGQIWANSFLPNEAEREDRLQKEYFAEQKSPMLVDYVQRELADGSRTVVETEHWLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPYSMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAERLRAVSDIHFRESGV
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: PYRD_PSEPK
Sequence: MYTLARQLLFKLSPETSHDLSLDLIGAGGRLGLNGMLCKQPASLPVSVMGLNFANPVGLAAGLDKNGAAIDGFAQLGFGFVEIGTVTPRPQPGNPKPRLFRLPEATAIINRMGFNNLGVDHLLGRVRASRYKGVLGINIGKNFDTPVERAVDDYLICLDKVYTAASYITVNVSSPNTPGLRSLQFGDSLKQLLDALAERREQLAGAHGKRVPLAIKIAPDMSDEETALVAAALMESGMDAVIATNTTLGREGVEALPYGGEAGGLSGAPVLEKSTHIVKVLAGELGGKLPIIAAGGITEGRHAAEKIAAGASLVQIYSGFIYKGPALIREAVDAIAAMPR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LPXK_ACTP2
Sequence: MNIWQSTSIITWLLAPFSLLFWLVSQIRLFLFRKKILKSYRSPVPVLVVGNISVGGNGKTPVVVWLVEQLQQRGVKVGVISRGYGGKSKDFPQLVTNQSSAEMVGDEPVLIVQRTGVPLAISANRQQSIELLLNQFKLDLIVTDDGLQHYALQRDIEWVVVDGIRRFGNGFVLPAGGLRELPSRLQSVQAIICNGGKAQPNEHLMTLEPEFAVNLRTGEQKPITDFIGQECVAIAGIGHPPRFFNMLENLGVKLLKTQGFADHQAFEPAQLKALAAEQIPLLMTEKDAVKCRTFAQQNWWYVPVSAKFSPESTACLLEPILKRLGK
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.