PharMolix/UniProtQA huggingface dataset:
Protein: SECB_ACIF5
Sequence: MDEQEAVFMIERIYVKDISFESPNAPLSFVQTEAPTVDVGLNTASTVVEGMEGLTEVTLTVTVKAKAGESTYFAVEVQQSGLFRVQNIPEEHMPALLAVHCPTILFPYAREVVADLVGRGGFQPLHLHPVNFEALYQQAQTQQQNYTTQ
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_PROM1
Sequence: MPLLNTITTPYAEAFLQVAESRNEVDEVVTQAKSILELWNSCPEFSDAMSSPVLEVNQKKAALEKLFSSQVTPSFLNLLKLLADRQRIGLLNSVLERLLEIYREQRNIALATITSASALNEDQQSELLKKVQSIAGTDNLEIDLKVDSELLGGFVVNVGSKVIDASIAGQVRRLGLALAKVS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: MEND_ECOUT
Sequence: MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLHAGGVHINCPFAEPLYGEMDDTGISWQQRLGDWWQDDKPWLREAPRRESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGAQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETTLVDAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: DNLJ_LEGPC
Sequence: MNDQGIKESIETLKEQIRKYDYHYYVLDEPLVPDAEYDRCFKALQQYEEQYPQFLSPDSPTQRVSGTPSDAFMPVAHKQAMLSLSNVFTTDELKAFIKRAIEKLDEPNQQLVFACEPKLDGLAVNMTYEGGILTHAATRGDGAVGENITANIKTIASVPLRLRVSNPPKLIEVRGEVYIPKADFEAYNARARELGEKTFANPRNAAAGSLRQLNPEISASRPLAIYCYGIGACEDYKLPNSHLEQLNLLKEFGFRVSPETRRAVGVEGCLDYYQYMLAKRNQLPFEIDGVVYKIDSISLQQQLGYVSRAPRFACAHKFPATEEMTRLIAVDFQVGRTGAVTPVARLEPVSVGGVTVSNATLHNFDEITRKDIHIGDTVIIRRAGDVIPEVVSVILEKRPANARKIELPKNCPVCGSEVVREADEAIARCVGGLYCKAQLKRMMWHFASRKAMYIEGLGSVLIDQLVDEGIVHHLADLYELDLQTLANLPRMGEKSAKNLLSALEKSKKTTFNRFLYALGIREIGEAGARVLAEHYCDVESLKAATIEELMTLNDIGPVAASHIVHFFAQAHNLEVIDRLLELGIHWPKPEKIQVNQQNPFFGKTVVLTGTLSTMGREEAKAKLLALGAKVSGSVSSKTDYLVAGSEAGSKLVKATELGVAIIEEDEFLKWVNS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MATK_PINDE
Sequence: MDEFHRCGKEDSFWQQCFLYPLFFQEDLYAISHDHYLDVSSSSRPMEHLSSNDQLSFLTVKRLIGQIRQQNHSIVLFVNCDPNPLADRKKSFYSESVLEALTLVLEVPFSIWSKSSVEGMNECKSFRSIHSIFPFLEDKFPHSNSILDARIPYSIHPEILVRTFRRWIRDAPSLHPLRSVLYDYRNSPENLQRSIIVVPRVNTRFFLFLLNYYVCECESILFSRLKRSSHSRSLDHGSFPQRTHFHRKIKHIIIFSRRNSLKSIWSLKDPKIHYVRYGERPIIAIKGADLLVKKCRYYLLIFRQFYFHLWSEPYRVCSHQLSKNCSSSPGYFLRVRMNPLLVRTKTLDELFIPVLITNEMDPIVPIVPIIGLLATEKFCDISGRPISKLSWTSLTDDDILDRFDQIWRNLFHYYSGSFDRDGLYRIKYILLLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFDSLPFSSKAAARSQRERIWHSDIPQINPLANSWQKIQDLKIENLFDQ
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LR75A_MOUSE
Sequence: MGTRQTKGSLAERASPGAAPGPRRERPDFWASLLLRAGDKAGRAGSGLPPYHRRVGMVQELLRMVRQGRREEAGTLLQHLRQDLGMESTSLDDVLYRYASFRNLVDPITHDLIISLARYIHCPKPEGDAMGAMEKLCRQLTYHLSPHSQWRRHRGLKRKPQACLKALLSGNPPDNMVDLSGIPLTSRDLERVTSYLQRCGEQVDSVELGFTGLTDDMVLQLLPALSTLPRLTTLALNGNRLTRALLRDLTDTLKDPSKFPNVTWIDLGNNVDIFSLPQPFLLSLRKRSPKQGHLPTILELGEGPGTGEEAREGTDQQDPIGSPVTPARGQESTECVIQT
What are the official names of this protein?
Leucine-rich repeat-containing protein 75A, Leucine-rich repeat-containing protein FAM211A.
What is the protein family that this protein belongs to?
Belongs to the LRRC75 family.
Protein: AFAD_MOUSE
Sequence: MSAGGRDEERRKLADIIHHWNANRLDLFEISQPTEDLEFHGVMRFYFQDKAAGNFATKCIRVSSTATTQDVIETLAEKFRPDMRMLSSPKYSLYEVHVSGERRLDIDEKPLVVQLNWNKDDREGRFVLKNENDAIPAKKAQSNGPEKQEKEGVIQNFKRTLSKKEKKEKKKKEKEALRQASDKEERPSQGDDSENSRLAAEVYKDMPETSFTRTISNPEVVMKRRRQQKLEKRMQEFRSSDGRPDSGGTLRIYADSLKPNIPYKTILLSTTDTADFAVAESLEKYGLEKENPKDYCIARVMLPPGAQHSDERGAKEIILDDDECPLQIFREWPSDKGILVFQLKRRPPDYIPKKMKKHVEGKSLKGKDRADGSGYGSALPPEKLPYLVELSPGRRNHFAYYSYHTYEDGSDSRDKPKLYRLQLSVTEVGTEKFDDNSIQLFGPGIQPHHCDLTNMDGVVTVTPRSMDAETYVDGQRISETTMLQSGMRLQFGTSHVFKFVDPIQDHVLSKRSVDGGLMVKGPRHKPGAVQETTFELGGDVHSGTALPASRSTTRLDSDRVSSASSTAERGMVKPMIRLDQEQEYRRRENRTQDATGPELILPASIEFRESSEDSFLSAIINYTNSSTVHFKLSPTYVLYMACRYVLSSQHRPDISPTERTHKAIAVVNKMVSMMEGVIQKQKNIAGALAFWMANASELLNFIKQDRDLSRITLDAQDVLAHLVQMAFKYLVHCLQSELNNYMPAFLDDPEENSLQRPKIDDVLHTLTGAMSLLRRCRVNAALTIQLFSQLFHFINMWLFNRLVTDPDSGLCSHYWGAIIRQQLGHIEAWAEKQGLELAADCHLSRIVQATTLLTMDKYVPDDIPNINSTCFKLNSLQLQALLQNYHCAPDEPFIPTDLIENVVAVAENTADELARSDGRDVQLEEDPDLQLPFLLPEDGYSCDVVRNIPNGLQEFLDPLCQRGFCRLVPHTRSPGTWTIYFEGADYESHLMRENAELAQPLRKEPEIITVTLKKQNGMGLSIVAAKGAGQDKLGIYVKSVVKGGAADVDGRLAAGDQLLSVDGRSLVGLSQERAAELMTRTSSVVTLEVAKQGAIYHGLATLLNQPSPMMQRISDRRGSGKPRPKSEGFELYNNSAQNGSPESPQMPWTEYSEPKKLPGDDRLMKNRADHRSSPNVANQPPSPGGKGPYTSGTAAKITSVSTGNLCTEEQSPPPRPEAYPIPTQTYTREYFTFPASKSQDRMAPPQSQWPNYEEKPHVHTESNHSSIAIQRVTRSQEELREEKVYQLERHRVEAGMDRKCDSDMWINQSSSVESSTSSQEHLNHSSKSVTPASTLTKSGPGRWKTPAAVLPTPVAVSQPIRTDLPPPPPPPPVHYTSEFDGIPMDLPLPPPPANQAGPQSAQVAAAEWKKREEHQRWYEKEKARLEEERERKRREQERKLGQMRSQTLNPASFSPLATQAKPEKPSTLQRPQETVIRELQPQQQPRTIERKDLQYITISKEELSSGDSLSPDPWKRDAREKLEKQQQMHIVDMLSKEIHELQNKVDRTAEESDRLRKLMLEWQFQKRLQESKQKDEDDDEEEDDDVDTMLIMQRLEAERRARMQDEERRRQQQLEEMRKREAEDRVRQEEDGRHQEEERVKRDAEEKRRQEEGYYSRLEAERRRQHEEAARRLLEPEEPGLSRPPLPRDYEPPSLSSAPCAPPPPPQRNASYLKTQVLSPDSLFTAKFVAYDEEEEDYGPAGPNSYSGSAGTAVGAYDAPREAREKLTRSQDADLPGSSGAPENLTFKERQRLFSQGQDVSDKVKASRKLTELENELNTK
What is the function of this protein?
Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs) (By similarity).  Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton (By similarity).  May play a key role in the organization of epithelial structures of the embryonic ectoderm (PubMed:10477764).  Essential for the organization of adherens junctions (By similarity).
What are the official names of this protein?
Afadin, Afadin adherens junction formation factor, Protein Af-6.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Note=Not found at cell-matrix AJs.
Protein: CDD_VIBA3
Sequence: MNSRITLALESAPTAIKALLSDIVLADNFDATLSPEQFASLLQASGLADDELRIALLPFAAAYSYAPLSDFYVGAIVRGLSGTLYFGANLEIAGAQLGQTVHAEQSAISHAWMKGEQGISDITINFSPCGHCRQFMNELTTAKELKVQLPQRDEMSLQEYLPDSFGPADLGVTTGLMTKLDHKHTTEETTPIVVEALAALNRSHAPYTKNLSGVSLQLTSGEVFTGAYAENAAFNPSLPPLQVALIQLKLAGFDFEQIENAALVEIAEGSISHLADTQSTLEAINPDIPVTYLAI
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: BMP3_XENLA
Sequence: MAECRPWLVLWVGCCGCLCLALGELLNDGLLAVGMGTGDAARQEEAALPLGDTVSEHMLRLYDKYRSGGGRAKESLRYRQALPDGNTVRSFRAMNGDEHKKCHYMFNLTSLTSSENILSATLHYYLGDLLNSSHRCPHSLFCTQHGHAKPEFTLYLTLWSFNALQNPTHVISNFLINVSASQRDHPLWQWKDITQAVRKAKEYGEAVLGFNLTIEYPNHRSIDILGLKPYILVYANDSAISEPDSVVSSLHGPHTPLALKPNRKTEKAEQRKKRSTEILLPLQNNELPGAEYQYSVDEEGWEERKPYKNLQGRQNEKDKNKKKLRKGSRQKSQTLQFDEQTLKKARRKQWNEPRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLSILFLDENKNVVLKVYPNMTVESCACR
What is the function of this protein?
Dorsalizing factor.  Antagonizes mesoderm formation by ventralizing BMPs.
What are the official names of this protein?
Bone morphogenetic protein 3, BMP-3, xBMP-3.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: DISA_KINRD
Sequence: MPDRTPDEVLRQTLAILAPGTDLRDGLERILRGRTGALIVLGFDRVVDSLSTGGFALDVEFSATRLRELAKMDGAIVLDRDVSRIVRAAVQLVPDSSIETSESGTRHRTAERVAKQTGFPVISVSQSMRIVAVYTGNRRYVLEGSDAILGRANQALQTLERYRARLDEVTGTLSALEIEDLVTVRDVCSVVQRIEMVSRIADEISGYVVELGVDGRLLSLQLDELVGGVGPDRELVVRDYLEASRYEGPLEAVLESLAGLHQSDLVDLSQVARVLGFSVGGDSLDSAVSPKGFRLLNRVPRLPGAIVERLVDQFGDLQKLLAASIDDLMTVDGVGEQRARAVREGLSRLAESSILERYV
What is the function of this protein?
Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP).  c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process.
What are the official names of this protein?
DNA integrity scanning protein DisA, Cyclic di-AMP synthase, c-di-AMP synthase, Diadenylate cyclase.
What is the protein family that this protein belongs to?
Belongs to the DisA family.
Protein: MURQ_CROS5
Sequence: MENIQERGHLLTEQINPNSQNLDQLSTVELVDLFNTEDAQTLKAIAQARIELAQAIDVTSKALGKGGRLFYVGAGTSGRLGVLDAAECPPTFCTDPDMVQGIIAGGAAALVRSSENLEDRPQDGAEAIAGRKVTEKDVVVGISAGGTTPYVHGALNAAKQRGATTIAMACVPAEQVPIVVDIDIRLLTGPEVLAGSTRLKAGTVTKMALNILSTGVMVKLGKVYGNRMIDVSVTNTKLYDRALRILEELTELSRQEAAELLDRSGKRVKLALLMHWAELDAEVGQLLLDNHHGNLRAALQAGQNS
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: PRP19_SCHPO
Sequence: MFCSISGETPKEPVISRVSGNVYEKRLIEQVIRETSKDPVTQQECTLEDLVPVKVPDFVRPRPPSATSLPALLSLFQEEWDSVALEQFELRRNLTETKQELSTALYSLDAALRVISRLTKERDEAREALAKFSDNIGTVSSKTIEVQEVEMGESDDQLKTSLRSTVEKTFQELSSKRKRTKLQPKWATDDAVSQLLQATPSTILENLETESTTSFFPSPENSSFVLCLHKDELLCLDIQSNSTLKIFEGSALACCWLTSSKIAVATADAISIFEFPVSSSGLQSVGEPTSSIPIDEKVNFLQAHPSGEYLLAASNEKCYIFSLKSQVYNITVAQHITSLAVHPDGNLFVAGLENGELRFFETSSGNELTKFGPHSSPVKTLQFGENGYWLVVTTNDDSDIFIWDLRKSELVQKIPLQTKVAAVSLDITSQLLVSSDGETLYVHIYVKSSKSWRCMSQTHVSSISNLVWLNELHQLLFSTSNGAILRLG
What is the function of this protein?
Probable ubiquitin-protein ligase involved in pre-mRNA splicing (By similarity).  May also function in DNA repair (By similarity).
What are the official names of this protein?
Pre-mRNA-processing factor 19, Complexed with cdc5 protein 8, RING-type E3 ubiquitin transferase PRP19.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PRP19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPX_CORK4
Sequence: MAGMQESADVLKCSFCGKSQKQVRKLIAGPGVYICDECIDLCNEIIEEEFDNSPAQKTDKALPKPSQIVDFLGDYVIGQDAAKRTLAVAVYNHYKRIQADENDHHKSDDDIEIAKSNILMLGPTGSGKTYLAQTLARMLDVPFAMTDATSLTEAGYVGEDVENILLKLLQAADFDVDRAQRGIIYIDEVDKISRKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPNQEFIQLDTKNVLFIVAGAFAGLEKVIGERRGKQGLGFGANVSSKEENELDAFSYVQPEDLVKFGLIPEFIGRLPVVATVNDLDREALVRVLTEPKNSLVKQYSRLLDMDGVTLTMEEGALNAIADKAIERGTGARGLRAILEEILGPVMFEVPDSEDVTEVVISEECVTEGAEPRLISSTEAERESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SYA_BRASO
Sequence: MSGVNEIRSTFLNFFAANGHEIVPSSPLVPRNDPTLMFTNAGMVQFKNVFTGVEKRPYHRATTSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKENAIELAWKLVTKEFGLPKDKLTATVYIDDDEAFGLWKKIAGLPESRIIRIAGSDNFWQMGDTGPCGPCSEIFYDHGDKIWGGPPGSAEADGDRFIEIWNLVFMQYEQLEGGVRNPLPKPSIDTGAGLERVAAVLQGKHDNYDIDLFVALIRAIADLTNADPQGPQKASLRVIADHLRASSFLISDGVLPSNEGRGYVLRRIMRRAMRHAQLLGAREPLMHKLVGALTREMGQAYPELIRAEGLIKETLRLEETRFRKTLERGLAILDEKSASLSKGDMFDGDVAFTLYDTYGFPLDLTQDALKSRGISVDQASFTDAMERQKAKARAAWAGSGEAATETVWFPLREKLGATEFLGYETETAEGAVTALVKDGAEVDSLKAGESGAIVLNQTPFYGESGGQVGDTGVLTGEGVRVRITDTQKKAGDLFAHIGTVEQGTLKLGTPLQLDVDHIRRSAIRANHSATHILHEALRQVLGDHIAQRGSLVSPDRLRFDFVHPKPITAEELARVEDIANDVVLENAEVTTRLMGLDDAREAGARALFGEKYGDEVRVVSMGNAARDHGNNAMGWSVELCGGTHVKRTGDIGLIAVTSESAVASGVRRIEALTARGARAHANHNLSLAKAAAAELRTTVDEVPARITALMEERKKLERELSDARKKLAMGGGAAAGGAAAGIREVAGIKLMARAVDGVEVKDLKSLVDEAKKQLGSGVVAIVGRSEDGKAGVVVGVTADLTARFNAVELVRAASEALGGKGGGGRPDMAQAGGPDGAKAEAALAAIESAIGKAG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_RALPJ
Sequence: MSDTAASMPYPVITIDGPTASGKGTVAHQIADLLGFHLLDSGSLYRLVALASMRENIDDHDVESLVRIARELDVRFKADRIWLKGEDVSLALRHESVGNQASAIAVHGAVREALHARQRAFLEAPGLVADGRDMGTVVFPEAVLKVFLTASVQARAERRYKQLIAKGFSATVESLSQDLEARDLRDRTRSVAPLRPAQDARQLDSSDMTVDEVVAQVLDWYRQVQGANKAN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: US9_EHV1A
Sequence: MEKAEAAAVVIPLSVSNPSYRGSGMSDQEVSEEQSAGDAWVSAAMAAAEAVAAAATSTGIDNTNDYTYTAASENGD
What is the function of this protein?
Essential for the anterograde spread of the infection throughout the host nervous system.  Together with the gE/gI heterodimer, US9 is involved in the sorting and transport of viral structural components toward axon tips (By similarity).
What are the official names of this protein?
Envelope protein US9 homolog, Envelope protein 76, ORF76 protein.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae envelope protein US9 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host Golgi apparatus membrane; Single-pass type II membrane protein. Host smooth endoplasmic reticulum membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN), maybe through an interaction with PACS-1 sorting protein.
Protein: Y1352_PSEPK
Sequence: MPSFDVVSELDKHEVQNAVDNAIKELDRRYDLKGKGTFEFKDKEQTVMLTAEEEFQLEAMLEILRLALVKRKIDVKCLETKDPYASGKEKKQEAKFREGIDKDLAKKIVATIKDGKLKVQAAIQGEQVRVTGKKRDDLQEAIALLRTKEFDMPLQFNNFRD
What are the official names of this protein?
UPF0234 protein PP_1352.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: SECY_BACLD
Sequence: MFKTISNFMRVKDIRNKIIFTLLMLIVFRLGSFIPVPHVNTEVLKAQDQMSVFGILNTFGGGALFNFSILAMGIMPYITASIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQALGMSYGFNNMAGGALITDPGVGTYLLIAIVLTAGTAFLMWLGEQITSHGVGNGISIIIFAGIVAGIPQTINQIYAQQFVDAGDQLFLQIIKVVVILVAILAIVVGVIFIQQAVRKISIQYAKGSGRSPVPGGQSTHLPLKVNPAGVIPVIFAVAFITTPRTVATFFGSNDVTNWIQKTFDYTHPVGMGVYAALIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGVRPGKMTQDRITSILYRLTFVGSIFLAVIAILPVLFVNIAGLPSSAQIGGTSLLIVIGVALETMKQLESQLVKRNYRGFMKH
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YAC1_MAIZE
Sequence: MQMVQLQIRVKMIWLLFMNHNHNHNHNQNHNHSHNLNPKKKHHRRGQRSAHRMYGSISPRRKLKWRSMERNTFRYGDIATFLIARLSIGLRVIMEQADFEIT
What are the official names of this protein?
Transposable element activator uncharacterized 12 kDa protein, AC 12 kDa protein.
Protein: HDG10_ARATH
Sequence: MDSSHNDSSSDEEGIDSNNRRHHSNHQVQRLEAFFHECPHPDDSQRRQLGNELNLKHKQIKFWFQNRRTQARIHNEKADNIALRVENMKIRCVNEAMEKALETVLCPPCGGPHGKEEQLCNLQKLRTKNVILKTEYERLSSYLTKHGGYSIPSVDALPDLHGPSTYGSTSNNRPASYGSSSNHLPQQSSLLRRPFTRELINTTPLPKPVLLQHFQQLSQLEKNRMFEIAKNAVAEVMSLIQMEHSMWIKSTIDGRAIIDPGNYKRYFTKNSHLKSRSALQSHHESSMEVVVVQMDARNLVDMFLNTEKWARLFPTIVTEAKTIHVLDSMDHPRQTFSRVVYEQLHILSPLVLPREFIILRTCQQMKEDLWLIADVSCYLQNVEFESTAPICTKRPSGVLIQALPHGRSKVTWIEHVEVTDKVWPHQLYRDLLYGGFGYGARRWTATLQRMCERLSLYSMTDFPPTDYPGVVKTIEGRRSVMSLGERMLKNFAWIMKMSDKLDLPQQSGANNSGVRISVRTNTEAGQPPGLIVCAGSSLSLPLPPLQVYDFLRNLEVRHQWDVHCQGNPVTEAARFVTGPDQKNNVTFLQPSSVGEYKLMILQDGFIDALGGMVVYAPMNLNTAYSAISGQVDPSTIPILPSGFIISRDSHPSSSEVDGGSMTLLTLAFQIFVTGPSYYTDLNLKDSATTVNTLVSSAVQRIKAMLNCE
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Homeobox-leucine zipper protein HDG10, HD-ZIP protein HDG10, Homeodomain GLABRA 2-like protein 10, Homeodomain transcription factor HDG10, Protein HOMEODOMAIN GLABROUS 10.
What is the protein family that this protein belongs to?
Belongs to the HD-ZIP homeobox family. Class IV subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: LEPA_ZYMMO
Sequence: MTPLDHIRNFSIIAHIDHGKSTLADRLIQTTGGLTAREMSEQVLDNMDIEKERGITIKAQTVRLDYTAKDGQKYVLNLMDTPGHVDFAYEVSRSLAACEGALLVVDASQGVEAQTLANVYQSIEYDHEIVPVINKIDLPAAEPEKVKQEIEEIIGLPADDAVLASAKSGIGIDDILEALVKRIPAPKGDINAPLKAMLVDSWYDPYLGVVILVRIIDGSLKKGQQIRFMQAGTTHLIDRVGCFRPKIEILDSLGPGEIGFITAQIKEVSQTAVGDTITDAKNPTSTPLPGFKQVQPVVFCGLFPVDAADFDKLKESLGKLRLNDASFSFEAENSAALGFGFRCGFLGLLHLEIIQERLSREYDLDLITTAPSVVYHLNMTHGEGSIDLHNPADMPDVTRIDSIDEPWIEATIYVPDQYLGAVLKLCQDRRGIQKDMTYVGGRVQLLYELPLNEVVFDFYDRLKSISRGYASFDYHQIGYREGDLVKMTIMVNGEVVDALSMIVHRHAAEGRGRQMCQRMKDLIPRHLFKIPIQAAIGGKVIARETIGAMRKDVTAKCYGGDISRKKKLLEKQKEGKKRMRQYGSVDIPQEAFIAALRMGDDS
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCE_LACLM
Sequence: MLYGKENRDEAEFLEPIFGSESEQVDLPKYKLAQQSIEPRVAYQLVQDEMLDEGNARLNLATFCQTYMEPEAVKLMSQTLEKNAIDKSEYPRTTEIENRCVNMIADLWNASEKEKFMGTSTIGSSEACMLGGMAMKFSWRKRAEKLGLDINAKKPNLVISSGYQVCWEKFCVYWDIEMREVPMDREHMSINLEKVMDYVDEYTIGVVGIMGITYTGRYDDIKALDNLIEEYNKQTDYKVYIHVDAASGGLYAPFVEPELEWDFRLKNVISINTSGHKYGLVYPGVGWVLWRDKKYLPEELIFKVSYLGGELPTMAINFSHSASQLIGQYYNFVRYGFDGYKAIHERTHKVAMYLAEEIEKTGMFEIMNDGAQLPIVCYKLKENSNRGWNLYDLADRLLMKGWQVPAYPLPKNLENEIIQRLVIRADFGMNMAFNYVQDMQEAIDALNKAHILFHQEPENKTYGFTH
What is the function of this protein?
Converts internalized glutamate to GABA and increases the internal pH.  Involved in glutamate-dependent acid resistance.
What are the official names of this protein?
Glutamate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: RS12_RICCK
Sequence: MPTYNQLVRFGRKSKTRKTKSPALESNPFKSGVCLVVKTVTPKKPNSALRKIATVRLSNKRTVNAYIPGEKHSVKEHDRVLVRGGQVPDLPGVKYHIVLGAYDIAGVKGRKQGRSRYGAPSKQVAVTKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SPIKE_ADE08
Sequence: MTKRLRAEDDFNPVYPYGYARNQNIPFLTPPFVSSNGFQNFPPGVLSLKLADPITINNQNVSLKVGGGLTLQEETGKLTVNTEPPLHLTNNKLGIALDAPFDVIDNKLTLLAGHGLSIITKETSTLPGLVNTLVVLTGKGIGTDLSNNGGNICVRVGEGGGLSFNDNGDLVAFNKKEDKRTLWTTPDTSPNCRIDQDKDSKLSLVLTKCGSQILANVSLIVVAGRYKIINNNTNPALKGFTIKLLFDKNGVLMESSNLGKSYWNFRNQNSIMSTAYEKAIGFMPNLVAYPKPTTGSKKYARDIVYGNIYLGGKPHQPVTIKTTFNQETGCEYSITFDFSWAKTYVNVEFETTSFTFSYIAQE
What is the function of this protein?
Forms spikes that protrude from each vertex of the icosahedral capsid.  Interacts with host sialic acid to provide virion initial attachment to target cell.  Fiber proteins are shed during virus entry, when virus is still at the cell surface.
What are the official names of this protein?
Fiber protein, SPIKE, Protein IV.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae fiber family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface.