PharMolix/UniProtQA huggingface dataset:
Protein: C1QT9_MOUSE
Sequence: MRIWWLLLVMGACTRSVFSQDTCRQGHSGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGHPGGPGKDGIRGEKGEPGADGRVEAKGIKGDPGSRGSPGKHGPKGSIGPTGEQGLPGETGPQGQKGDKGEVGPTGPEGLMGSTGPLGPKGLPGPMGPIGKPGPRGEAGPMGPQGEPGVRGMRGWKGDRGEKGKVGEAPLVPKSAFTVGLTVISKFPPPDAPIKFDKILYNELNHYNVATGKFTCHVAGVYYFTYHITVFSRNVQVSLVKNGVKVLHTKDSYMSSEDQASGGIVQELKLGDEVWMQVTGGERFNGLFADEDDDTTFTGFLLFSSS
What is the function of this protein?
Probable adipokine.  Activates AMPK, AKT, and p44/42 MAPK signaling pathways.
What are the official names of this protein?
Complement C1q and tumor necrosis factor-related protein 9.
Protein: GCH1_NITMU
Sequence: MDSNDSEFGIGDWQRLLRSLGEDPSRQGLRETPERVTRAWAHWTRGYKQDPAAILKTFADGGESYDELIVVRQIPVYSHCEHHLAPFFGHATIGYLPTGHIVGLSKLTRLVNCFAARLQVQERLTQQVAQSLLEHLQPKAVGVILRCRHMCMESRGIAVAGEETVTSAMLGDLKTNAAQRAEFLALAESHE
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: GK_VZVO
Sequence: MQALGIKTEHFIIMCLLSGHAVFTLWYTARVKFEHECVYATTVINGGPVVWGSYNNSLIYVTFVNHSTFLDGLSGYDYSCRENLLSGDTMVKTAISTPLHDKIRIVLGTRNCHAYFWCVQLKMIFFAWFVYGMYLQFRRIRRMFGPFRSSCELISPTSYSLNYVTRVISNILLGYPYTKLARLLCDVSMRRDGMSKVFNADPISFLYMHKGVTLLMLLEVIAHISSGCIVLLTLGVAYTPCALLYPTYIRILAWVVVCTLAIVELISYVRPKPTKDNHLNHINTGGIRGICTTCCATVMSGLAIKCFYIVIFAIAVVIFMHYEQRVQVSLFGESENSQKH
What is the function of this protein?
Glycoprotein that probably modulates membrane fusion events during secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.  Also plays a role, together with gB, in virus-induced cell-to-cell fusion (syncytia formation), which is extensive during VZV infection in cultured cells (By similarity).
What are the official names of this protein?
Envelope glycoprotein K, Syncytial protein.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein K family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein. Host endosome membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported with UL20 to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN). Cell surface expression of gK is required for virus-induced cell-to-cell fusion. Likely not present in extracellular virions (By similarity).
Protein: CRBB3_HUMAN
Sequence: MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQVESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPHHKLHLFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGEYRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Beta-crystallin B3, Beta-B3 crystallin.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: PK21C_RHIME
Sequence: MDKHTDDRKKNNHWKAEDRKSAATEASETRSGGNYAKELARLQEEIAHLQAWVKKTGARIVIVFEGRDAAGKGGVIKRITERVSPRVFRVVALPAPTDREKTQIYMQRYIQQFPAAGEVVIFDRSWYNRPGVERVMGFCSEKKAKRFLEIAPRFEAAMIESGIVLLKYFLDVSEEEQDRRFRQRINDPLRQWKLSPMDVESYRRWWDYTRAYDEMIRMTDTDDAPWWIVPSDNKKQARVNCIAHILSSIPYERVKFEDPDLGKRQKRPADFEGDTRRRTVPNLF
What is the function of this protein?
Uses inorganic polyphosphate (polyP) as a donor to convert ADP to ATP.  Can also convert GDP to GTP, with lower efficiency.
What are the official names of this protein?
ADP-polyphosphate phosphotransferase 3, Polyphosphate kinase PPK2 3.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
Protein: ISF2_ARCFU
Sequence: MIVGISGSPRRKATEFVLGEALKMLEERGFETKFFTVRGKKISPCQHCDYCLKHKECRIKDDMFELYEMLKDAKGIVMATPVYNGGVSAQIKAVMDRCRALVAADYDFFRGKVGMAIAVGGDRIGGQELAIQQILTFYILNGVIPVSGGSFGANIGATFWSRDTLEGVKEDEEGFRSLRKTVKRFAEMLEKMEGV
What is the function of this protein?
Redox-active protein probably involved in electron transport.
What are the official names of this protein?
Iron-sulfur flavoprotein AF_1519, AF-2, Af2, Isf-2.
What is the protein family that this protein belongs to?
Belongs to the SsuE family. Isf subfamily.
Protein: ARGR_LISIN
Sequence: MNKGHRHIIIRELITSNEIDTQEDLVELLLERDVKVTQATVSRDIKELHLVKVPTQTGGYKYSLPADNSFNPHQKLKRALIDCFICIDTVQFMIILKVMPGNGNSVGALIDNLDWPEKAGTLCGDDTCLIICRSEENAKTLTDRFIDML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENTP7_HUMAN
Sequence: MARISFSYLCPASWYFTVPTVSPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSASLPRDRQYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEATQELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGLSPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQSPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADEHRLKYQCFKSAWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFLPLRDLRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAPLDLLWLEEVVPMMGVQVGP
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner.  Preferentially hydrolyzes nucleoside 5'-triphosphates, with substrate preference for UTP > GTP > CTP.  Hydrolyzes ATP and nucleoside diphosphates only to a minor extent.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 7, NTPDase 7, Lysosomal apyrase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: MAO1_VIBVU
Sequence: MNNDKRPLYIPFAGPALLSTPLLNKGSAFSAEERISFNLEGLLPETTETIQEQVERAYMQYKAFESDMDKHIYLRNIQDTNETLFYRLVQNHITEMMPIIYTPTVGAACENFSNIYRRGRGLFVSYANRDRIDDILNNASNHNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPIVLDVGTNNPQRLADPMYMGWRHPRITGADYDAFVEEFIQAVQRRWPDALIQFEDFAQKNAMPLLERYKNRICCFNDDIQGTAAVTVGSLMAACQAAGSKLSEQRITFLGAGSAGCGIAEAIIAQMVSEGISDKKARSQVFMVDRWGLLQEGMPNLLDFQQRLVQKHSVTAKWETEANGFSLLDVVKNAKPTVLIGVSGAPGLFTQEVIQEMHKHCPRPIVFPLSNPTSRVEAVPADIIRWTNGDALVATGSPFDPVIHEGKTYPIVQCNNSYIFPGIGLGVLAVNAKRVTDEMLMESSRALATCSPLAINGKGALLPPLEEIHTVSKRIAYAVAKKAIEQGVALEIADDALQVAIEQHFWQPVYRRYKRTAF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: GLPK_SULIM
Sequence: MNTMSHKFVLALDEGTTSARAILFDSDLNIVNIGQYEFPQHYPQPGYVEHDPEEIWEAQMLAVKKAISKIDAKQIVAIGITNQRETTVLWDAKSGKPVYNAIVWQDRRTSPITDWLKANYFKMIKDKTGLVPDPYFSASKIKWILDNVSNVREKAERGEIKFGTIDTYLIWRLTNGKAHVTDYSNASRTMLFNINKLEWDREILELLKIPESILPEVKPSSEIYGYSEALGNLIPISGDAGDQQAALFGQVAFNVGEIKATYGTGSFILMNIGNNPIRSENLLTTIAWGLEKNKAKYALEGSIFITGAAVQWFRDGLRAIDVSDEIEPLASSVEDNGGVYFVPAFVGLGAPYWDPYARGLIIGITRGTTKAHIARAILESMAYQTRDVIEVMQKEAGISINSLKVDGGAAKDNLLMQFQADILGIKVIRPKVMETTSMGVAMLAGLGVGLWNSLEELRNIWKVDKEFIPSMSEEKRRALYSGWKEAVKRAMGWAKVVGGQV
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y1886_METB6
Sequence: MGDDELSEIRKRRMAQLQQQAGDQQAMQEEVERQQRLKSQIQMVLMQVLEPDARERLNTIRLTKPDFASAVEQQLVMLAQSGRLRQKITDAQLKDLLRQLAPAKRDYSITRK
What are the official names of this protein?
DNA-binding protein Mboo_1886.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: CSTM9_ARATH
Sequence: MNPSEQNHLSVEKPSQTSSGPYTSPPPIGYPTRDAMVGDPPAAAVETKSKGDGFWKGCCAAICCCCVLDACF
What is the function of this protein?
Involved in resistance to abiotic stress.
What are the official names of this protein?
Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 9, AthCYSTM9.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Nucleus.
Protein: LIPA_BRUME
Sequence: MVTVLNTVNQSGRLRHPEKAHRPDNEVLKKPDWIRVKAPVSRGYGETREIVRSNKLVTVCEEAGCPNIGECWEKKHATFMIMGEICTRACAFCNISTGIPNALDPNEPENIAKAVKQMGLTHVVITSVDRDDLADGGAHHFAEVIKAVREAAPATTIEILTPDFLRKEGALEIVVKARPDVFNHNLETVPSKYLKVRPGARYFHSIRLLQRVKELDPTIFTKSGIMVGLGEERNEILQLMDDLRSADVDFMTIGQYLQPTRKHHPVIRFVKPDEFKSFETIGKTKGFLLVASSPLTRSSHHAGEDFAKLKAAREALYASRAS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_GLOC7
Sequence: MTKFVFVTGGVVSSIGKGIVAASLGRLFKSRDYSVSILKLDPYINVDPGTMSPFQHGEVFVTDDGAETDLDLGHYERFTDTPMSRLNSVTTGSIYQAVINKERRGDYMGGTVQVIPHITNEIKERIHRVAKNTNPDIVIIEIGGTVGDIESLPFLEAIRQFRKEVGRNNVVYMHVTLIPWIPAAGEMKTKPTQHSVKELRSIGIQPDVLVCRCDRPLQPGLKEKLSAFCDVPVASVIMSQDASTIYQVPLNLEEEGLAQQTLELLNLEPRQPDLSQWRTLVQQMQSPSKQIEVALVGKYVQLSDAYLSVVEALGHAAIATNSVVKIRWVSAEDLENDSAEQHLEGVSGIVVPGGFGVRGVDGKVRAIEYARHHNIPFLGLCMGMQCSVIEWARNIAHLEKANSAEFDRESPNPVINLLPEQQDVVDLGGTMRLGLYPCRLTPDTQTFALYKQEVVYERHRHRYEFNNAYRSLFLETGYVISGTSPDGRLVEIIELPGHPFFIATQFHPEFRSRPSTPHPLFLGFVKASVDYNHVSLDSKIQTHIELVTEENTPSIALG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: UBC12_BOVIN
Sequence: MIKLFSLKQQKKEEESAGGTKGSSKKASAAQLRIQKDINELNLPKTCDISFSDPDDLLNFKLVICPDEGFYKSGKFVFSFKVGQGYPHDPPKVKCETMVYHPNIDLEGNVCLNILREDWKPVLTINSIIYGLQYLFLEPNPEDPLNKEAAEVLQNNRRLFEQNVQRSMRGGYIGSTYFERCLK
What is the function of this protein?
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins.  The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4.  Involved in cell proliferation.
What are the official names of this protein?
NEDD8-conjugating enzyme Ubc12, NEDD8 carrier protein, Ubiquitin-conjugating enzyme E2 M.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBC12 subfamily.
Protein: RL22_STRPQ
Sequence: MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTPNKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: TRPD_HERA2
Sequence: MQIRDAIITVTNRTDLSQDDAAAVMEQMMNGEATPAQIAALLTALHFKGETDAEIAGMAQVMRAKSLAVPHDGGVVDTCGTGGDHSNTFNISTTAAFVAAGAGATVAKHGNRAMSSKCGSADVLEGLGVNIELDAEGVARCLRQAGIGFMFAPKFHPAMRYAGPVRREIGIRTIFNVLGPLTNPARAEYQVIGVANAGLAEKLANALSKMGIRRALVVHGSDGLDEISISASTLVFDVRAGATPQASTISPSDFGLSLAPREAIAGGSVEENVAMTKAILEGSDTGPRRDIVLLNAAAALVACERADSFGEALRQAQQAIDTGSANQRMQRMIEASNG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: RL14_BIFAA
Sequence: MIQQETRLHVADNTGAKELLAIRVLGGSKRRYAGIGDVIVASVKDAIPGGSVKKGDVVKAVVVRTVKEHRRVDGSYIKFDENAAVILGSGREPKGTRIFGPVGRELRDKRFMKIVSLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CCR5_RAT
Sequence: MDFQGSIPTYIYDIDYSMSAPCQKVNVKQIAAQLLPPLYSLVFIFGFVGNMMVFLILISCKKLKSMTDIYLFNLAISDLLFLLTLPFWAHYAANEWVFGNIMCKLFTGIYHIGYFGGIFFIILLTIDRYLAIVHAVFAIKARTVNFGVITSVVTWVVAVFVSLPEIIFMRSQKEGSHYTCSPHFLHIQYRFWKHFQTLKMVILSLILPLLVMVICYSGILNTLFRCRNEKKRHRAVRLIFAIMIVYFLFWTPYNIVLLLTTFQEYFGLNNCSSSNRLDQAMQVTETLGMTHCCLNPVIYAFVGEKFRNYLSVFFRKHIVKRFCKHCSIFQQVNPDRVSSVYTRSTGEQEVSTGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, MIP-1 alpha receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y751_MYCTO
Sequence: MTYTGSIRCEGDTWDLASSVGATATMVAAARAMATRAANPLINDQFAEPLVRAVGVDVLTRLASGELTASDIDDPERPNASMVRMAEHHAVRTKFFDEFFMDATRAGIRQVVILASGLDSRAYRLAWPAQTVVYEIDQPQVMEFKTRTLAELGATPTADRRVVTADLRADWPTALGAAGFDPTQPTAWSAEGLLRYLPPEAQDRLLDNVTALSVPDSRFATESIRNFKPHHEERMRERMTILANRWRAYGFDLDMNELVYFGDRNEPASYLSDNGWLLTEIKSQDLLTANGFQPFEDEEVPLPDFFYVSARLQRKHRQYPAHRKPAPSWRHTACPVNELSKSAAYTMTRSDAHQASTTAPPPPGLTG
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MT0751.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: NARF_BRUMA
Sequence: MNDDDFGFSGIIKIANVSDFIAPSQACILPLQSKESDVEVQIRVRSRAKKVDDSAVKKVEVTLKDCLACSGCITSAETILIKEQSKPKFLEGLKKAQLSVMTVSPQSIASIAYKRGCHLSEAARLIARIFMNMGMKYVVDSSFGRLLTLSLSYDEFKESQLQRPIFTGVCPGFVCYAEKTHGTLLIPHISCVRSPQAMMGALVKDYLARKFNVRPEEIFHASVMPCFDKKLEAARSHSENHFNCREVDCVLSTGEVDAILDECSSTESFPVDGKVGWLNALENGKIISSEGGSSGGYAEYIVKRFVEESKTPLKLKRTIKDKNWEIIEAVDGETIVLSVAKCYGFRNIQNQVQKLKRSKCNYDYVEIMACPSGCINGGGQIRSASIEERKQLLDTIELPCSEDNSEMEEQLERVKEEWSILNPDWMNLLYTKYHAVVKSDADRISTNW
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for maturation of extramitochondrial Fe/S proteins (By similarity).
What are the official names of this protein?
Probable cytosolic Fe-S cluster assembly factor Bm1_25010.
What is the protein family that this protein belongs to?
Belongs to the NARF family.
Protein: BOA3_BOTFB
Sequence: MFAVELLERLGLPTIYLWIGFVLVVLLAYPTYFAIYNLYFHPLRKFPGPLIARSSYIWYAKNWIGGRWPHALSDLHEKYGQVVRIAPDELAFSSAQSWRDIYGHSVKGKKYFRKTDWYAGVGDLPNSISTEPDPQKHSAMRRVLANAFSNSVLKGQADVINKYLDMFVSQIKKHDNPNGIPVEEWFNWLTFDIIGDLTFHESFGAVENARTHFWIHLIINGNFIRSLYPIFQKIPISRLFMKWIIPNMDEIRQQRREHIAHTNSKAMKRANRDDIVQKDFFSFLLGKEGADTSEMFLTAQAHTLIIAGSETTAVTLTAMVSFLLRYPDKMKILIDEVRGAFTDKSQINVEGTLPLEYLFAVIEETLRILPPVPFGLPRTCPGAVIDGHVVPEGTIVSVSPYTASHDVRYWHDPEGWHPERWLPSDHPLHNPVFDQDNKEASKPFSTGPRVCLGVNLAYIELRMTLARLLFEFDMELLSKPVDWNTELDFFQFWKKVETRVKFTSLH
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster A that mediates the biosynthesis of botcinic acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial (PubMed:18208491, PubMed:21722295).  Botcinic acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities (PubMed:18208491, PubMed:21722295).  Two polyketide synthases, BOA6 and BOA9, are involved in the biosynthesis of botcinins.  BOA6 mediates the formation of the per-methylated tetraketide core by condensation of four units of malonyl-CoA with one unit of acetyl-CoA, which would be methylated in activated methylene groups to yield a bicyclic acid intermediate that could then either be converted to botrylactone derivatives or lose the starter acetate unit through a retro-Claisen type C-C bond cleavage to yield botcinin derivatives (PubMed:23203902).  The second polyketide synthase, BOA9, is probably required for the biosynthesis of the tetraketide side chain of botcinins (Probable).  The methyltransferase (MT) domain within BOA6 is probably responsible for the incorporation of four methyl groups (Probable).  The trans-enoyl reductase BOA5 might take over the enoyl reductase function of BOA6 that misses an ER domain (Probable).  The monooxygenases BOA2, BOA3 and BOA4 might be involved in further hydroxylations at C4, C5 and C8, whereas BOA7, close to BOA9, could potentially be involved in the hydroxylation at C4 in the side chain of botcinins (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase BOA3, Botcinic acid biosynthesis cluster A protein 3.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MURG_CLAM3
Sequence: MTVYLLAGGGTAGHVNPLLAVADELRAREPGSTILVLGTREGLESRLVPARGYELLTIARLPFPRRPDGAAVRFAPAFARAVGQIRRMIAERGIDVVVGFGGYAAAPAYAAARRPGVPVVVHEANASPGLANRLGARVAAAVGITFPGTALGPRAEVVGMPLRREIATLDRAAVRDAARAELGLDADRPTLLVTGGSTGARSLNRTVVQVAERITATGAQILHIVGGAQEFTDPGVERYHVVGYSDRMELAIAAADLVVSRAGAGALSELTAVGVPAVYVPYPVGNGEQAVNVRGVVAAGGGIVVADADFTPDWVLAHVLPLLSDPAALARMSQAAASVGTRDGAARMADLVRDAVAARPSRPAARR
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL6_METSB
Sequence: MSRIGKKPVAIPSGVTANVDGQLISVKGGKGQLSFAAPEDVTVVLGDGGIEVSPRNETKRARAMWGMTRSMVNNLVVGVSKGFERKLEITGVGYKAAVSGKNLQLSLGFSHDVTFPIPDGISIVAAKPTEVAISGIDKRQVGQIASEIRALRPPEPYKGKGVKYAGEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RECA_CLONN
Sequence: MNNEKMKALQAAITQIEKQFGKGSVMKLGEEHVLNVEAISTGSLSLDIALGIGGIPRGRIIEIFGPESSGKTTVALHIIAEAQKSGGTAAFIDAEHALDPVYAKALGVDIDNLIVSQPDTGEQALEICEALVRSGAIDVIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSINKSKCATIFINQLREKVGIMFGNPETTPGGRALKFYSSVRLDVRKIETIKQGDEFLGSRTRVKVVKNKVAPPFKQAEFDIMYGTGISFEGNVLDVGVDNEIIQKSGSWFSYNDTRLGQGRENVKQFLRENPSILLEVENKIREKHNLKTRNTADSKVTGAKDEKSKEEK
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_LISMH
Sequence: MSTNNSDIRVVVGMSGGVDSSVTAHILKEQGYDVIGIFMKNWDDTDEFGVCTATEDYDDVIRVANQIGIPYYAVNFEKEYWDKVFTYFLDEYKLGRTPNPDVMCNKEIKFKAFLEHAESLGADFVATGHYAQVKKVGDEIELLRGVDNNKDQTYFLNQLSQDQLKKVMFPLGAMEKTEVREIAKKAGLATANKKDSTGICFIGERNFKQFLSEYLPAQPGEMRTLNGEVLGKHDGLMYYTIGQRHGLGIGGDGEPWFVVGKDLKENVLFVEQGFHHETLYSDSLIATDISFTTNAAKPKTIECTAKFRYRQTDTKVTVHLREDGTAEVVFADPVRAITPGQAVVFYDGDICLGGGTIDTVWKNGAKLNYVG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGP3_MYCGE
Sequence: MKTMRKQIYKKAYWLLLPFLPLALANTFLVKEDSKNVTAYTPFATPITDSKSDLVSLAQLDSSYQIADQTIHNTNLFVLFKSRDVKVKYESSGSNNISFDSTSQGEKPSYVVEFTNSTNIGIKWTMVKKYQLDVPNVSSDMNQVLKNLILEQPLTKYTLNSSLAKEKGKTQREVHLGSGQANQWTSQRNQHDLNNNPSPNASTGFKLTTGNAYRKLSESWPIYEPIDGTKQGKGKDSSGWSSTEENEAKNDAPSVSGGGSSSGTFNKYLNTKQALESIGILFDDQTPRNVITQLYYASTSKLAVTNNHIVVMGNSFLPSMWYWVVERSAQENASNKPTWFANTNLDWGEDKQKQFVENQLGYKETTSTNSHNFHSKSFTQPAYLISGIDSVNDQIIFSGFKAGSVGYDSSSSSSSSSSSSTKDQALAWSTTTSLDSKTGYKDLVTNDTGLNGPINGSFSIQDTFSFVVPYSGNHTNNGTTGPIKTAYPVKKDQKSTVKINSLINATPLNSYGDEGIGVFDALGLNYNFKSNQERLPSRTDQIFVYGIVSPNELRSAKSSADSTGSDTKVNWSNTQSRYLPVPYNYSEGIIDADGFKRPENRGASVTTFSGLKSIAPDGFANSIANFSVGLKAGIDPNPVMSGKKANYGAVVLTRGGVVRLNFNPGNDSLLSTTDNNIAPISFSFTPFTAAESAVDLTTFKEVTYNQESGLWSYIFDSSLKPSHDGKQTPVTDNMGFSVITVSRTGIELNQDQATTTLDVAPSALAVQSGIQSTTQTLTGVLPLSEEFSAVIAKDSDQNKIDIYKNNNGLFEIDTQLSNSVATNNGGLAPSYTENRVDAWGKVEFADNSVLQARNLVDKTVDEIINTPEILNSFFRFTPAFEDQKATLVATKQSDTSLSVSPRIQFLDGNFYDLNSTIAGVPLNIGFPSRVFAGFAALPAWVIPVSVGSSVGILFILLVLGLGIGIPMYRVRKLQDASFVNVFKKVDTLTTAVGSVYKKIITQTGVVKKAPSALKAANPSVKKPAAFLKPPVQPPSKPEGEQKAVEVKSEETKS
What are the official names of this protein?
Mgp-operon protein 3, Mgp3, ORF-3 protein.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.