PharMolix/UniProtQA huggingface dataset:
Protein: SECA1_CLOD6
Sequence: MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNMTNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKTGEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQNPKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEARTPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDNITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQAIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVPTNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKKKGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRRNGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLAIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLEEDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGEDLQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEITEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRAVGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSDGTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: BUB31_ARATH
Sequence: MTTVTPSAGRELSNPPSDGISNLRFSNNSDHLLVSSWDKRVRLYDVSTNSLKGEFLHGGAVLDCCFHDDFSGFSVGADYKVRRIVFNVGKEDILGTHDKAVRCVEYSYAAGQVITGSWDKTVKCWDPRGASGPERTQVGTYLQPERVYSMSLVGHRLVVATAGRHVNIYDLRNMSQPEQRRESSLKYQTRCVRCYPNGTGYALSSVEGRVAMEFFDLSEAAQAKKYAFKCHRKSEAGRDIVYPVNSIAFHPIYGTFATGGCDGFVNIWDGNNKKRLYQYSKYPTSISALSFSRDGQLLAVASSYTFEEGEKSQEPEAIFVRSVNEIEVKPKPKVYPNPAA
What is the function of this protein?
Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments.  Promotes the formation of stable end-on bipolar attachments.  Necessary for kinetochore localization of BUB1.  The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20 (By similarity).  Essential for gametophyte development.
What are the official names of this protein?
Mitotic checkpoint protein BUB3.1, Protein BUDDING UNINHIBITED BY BENZYMIDAZOL 3.1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BUB3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cytoskeleton, spindle. Note=Accumulates onto both kinetochores and the spindle microtubules in cell arrested in metaphase. Starts to localize at kinetochores in prometaphase I (Pro-MI) stage and maintains the localization until the metaphase I-anaphase I (MI-AI) transition. Associates with unattached kinetochores upon spindle assembly checkpoint (SAC) activation. Present in the phragmoplast midline during the final step of cell division.
Protein: ZUPT_ECO7I
Sequence: MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPVYAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAVVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG
What is the function of this protein?
Mediates zinc uptake.  May also transport other divalent cations.
What are the official names of this protein?
Zinc transporter ZupT.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL27_THEFY
Sequence: MAHKKGASSSRNGRDSNAKRLGVKRFGGQYVKAGEILVRQRGTRFHPGDNVGRGGDDTLFALVAGRVEFGNLRGRKAVSVIPTPVASE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RRP36_ASPFU
Sequence: MAVSDLLNRRVRALPDEDEELYSEASVSELESNDEEVEGSGSDISDDSSEGDYSSDSQDESDAMSHENEEEDDEDDENSDDGQDDVQASLSNISFGALAKAQASLGPTAKRKSKATQSKTDDGETPAASPLDDIRARIREAREQKREGSSKSKDLEKFSRSSKHAPMVQSSKHPVTRKRTIIEPPAALKSRDPRFDPAVRSQSGRSEASQSAYAFLDDYRAAELKEMKEKLAKTKDPRQKEALKRDIRSATDRLRTIENRRREKEVLAEHKKREKELIREGKKSTPYFLKKSELKKQALLKKYESMGSRQRVKALERRQKKLTAKERKEMPMERRGLGNDPTPYNDGGGGKRRRLA
What is the function of this protein?
Component of the 90S pre-ribosome involved in the maturation of rRNAs.  Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity).
What are the official names of this protein?
rRNA biogenesis protein rrp36, Ribosomal RNA-processing protein 36.
What is the protein family that this protein belongs to?
Belongs to the RRP36 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MBTM_MYCSS
Sequence: MASALADAMTSSGRDLVVLDHGGWRRHPWAEVHQRAENIAARITEDAATVVVLVGEPTVEFIAAIPGTLYAGAALSILPGPVRGADLGQWARNTMQRCASIGVRLVFSHGEHLDALRATPASIPTCDVTETGHARRDSSFTPPDHGEFAVLQGTAGSTGIPRTAQLSPEAVLANLRGLVACIDITPADTGCSWLPLYHDMGLAFLLTNALGGAELWQAPTTAFSASPFSWLQWMTESTATLTAAPNMAYGLIGKYGSRLTDFDLGALRFALNGGEPVDCQGYRRFATEMARFGLDPSALVPAYGLAESSCAVTVPILGSGLQVDEVQVSSDDGRFIRTHAVVGEPIPGMQVRIAPTDGSGEQVDGRDFGEIEVRGTSLMSGYLGEPPLEAGSWFPTGDLGYFVDSGLVVCGRAKELITVAGRNIFPAEVERVAAQVQGVREGAVVAVGTDESAVRPGLVIAAEFRGTDEPAARTELVQRVASECGVVPSNVVFLEPGALPRTSSGKLRRLEVKRSMEDVNR
What is the function of this protein?
Activates lipidic moieties required for mycobactin biosynthesis.  Converts medium- to long-chain aliphatic fatty acids into acyl adenylate, which is further transferred on to the phosphopantetheine arm of the carrier protein MbtL.
What are the official names of this protein?
Medium/long-chain-fatty-acid--[acyl-carrier-protein] ligase MbtM, Fatty acyl-[acyl-carrier-protein] synthetase, Fatty acyl-ACP synthetase, Mycobactin synthetase protein M.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: OFT39_ARATH
Sequence: MNPYDAKDRRWILSMFFFVVLFCNNVSTSSSSSEVITIKPRHLSLLKSALQRSSGEQSDLWRPLTDQGWSPCIDLGNSPSLPDKTAGYVQVFLDGGLNQQRMGICDAVAVAKILNATLVIPYLEVNPVWQDSSSFVDIFDVDHFIDSLKDDIRVVRELPDEYSWSTREYYGTAVRETRVKTAPVHASANWYIENVSPVLQSYGIAAISPFSHRLSFDHLPAEIQRLRCKVNFQALRFVPHITSLGDALVSRLRNPSWRSNKEQKNVDHLGDMTNPHRRQEPGKFAVLHLRFDKDMAAHSACDFGGGKAEKLSLAKYRQMIWQGRVLNSQFTDEELRSQGRCPLTPEEMGLLLAAFGFDNNTRLYLASHKVYGGEARISTLRQVFPRMEDKRSLASSEERARIKGKASLLAALDYYVSMHSDIFISASPGNMHNALVGHRTFENLKTIRPNMALIGQLFLNKSITWVDFQQALGEGHVNRQGQIRLRKPKQSIYTYPAPDCMCHV
What are the official names of this protein?
O-fucosyltransferase 39, O-FucT-39, O-fucosyltransferase family protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase GT106 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: NUOG_ECOL6
Sequence: MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGACRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHDCPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRYYKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRKWDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLKDRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGEENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALAVRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAPVEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNTGSAEVIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVVLENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNEGRAQRFFQVYDPAYYDSQTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPELAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEGNNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENSLDYFTSVPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGTRVSFSYDGNMVTLPVEISEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit G, NADH dehydrogenase I subunit G, NDH-1 subunit G, NUO7.
What is the protein family that this protein belongs to?
Belongs to the complex I 75 kDa subunit family.
Protein: YWQO_BACSU
Sequence: MKFLLSVIAGLLILALYLFWKVQPPVWIQVETNSSQLKQSVRMAGTTLQVKHMIKSDAGEETAVISNGISGLK
What are the official names of this protein?
Uncharacterized protein YwqO.
Protein: HXB2A_DANRE
Sequence: MNFEFEREIGFINSQPSLAECLTSFPAVLESFQTSSIKDSTAIPPPFEHTIPSLSPCTGNQARPRSQKRTASNGLQLRTQTAPPTQHQQGPAPLSGGAPLAHEFPWMKEKKSSKKCPKPGATAAAAAASPSQASSGYTTAGLESPTEIQGGLDNVSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTTHHRDGQEGEPSGFDLLEGTDASSPYSSQSLEVSGSGSAAPSESETCPTTAAYTNSSDKSQPTPEEGQASQPEPASVPDTAVHSPPYPTPTADNPTTMAEGRAAGPEHSFTEPQDATSLPDLNFFSTDSCLQISDALSPSLQSSLDSPVDFSEEDFDLFTSTLCTIDLQHLQF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Plays an important role in the patterning of hindbrain and pharyngeal arches.
What are the official names of this protein?
Homeobox protein Hox-B2a, Hox-B2.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family. Proboscipedia subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: UPPP_YERE8
Sequence: MTDMYSLFVAFVLGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGKVPHEGKTNGHLTLGHILLAMIPAVGLGLAFHDVIKSLFNPQSVMYALVAGGLLLLAAEWFKPKNPKATGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMLGASGLDLYKSLHFLSWGDLPMFAVGFITAFVVALIAIKTFLSLIKRISFVPFAIYRFIVAAAVYWVFM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEMH_SALPB
Sequence: MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTPRLLWWPLLRGVILPLRSPRVAKLYQSIWMDGGSPLMVYSREQQQALAARLPDTPVALGMSYGSPSLESAVDELLASDVDHIVVLPLYPQYSCSTVGAVWDELGRILARKRRIPGISFIRDYADDSAYIDALAKSARESFARHGEPDVLLLSYHGIPQRYADEGDDYPQRCRDTTRELVSALGLPPEKVMMTFQSRFGREPWLTPYTDETLKMLGEKGTGHIQVMCPGFAADCLETLEEIAEQNREIFLEAGGKKYAYIPALNATPEHIDMMLKLTAPYR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHA_MYCBP
Sequence: MAGVRHDDGSGLIAQRRPVRGEGATRSRGPSGPSNRNVSAADDPRRVALLAVHTSPLAQPGTGDAGGMNVYMLQSALHLARRGIEVEIFTRATASADPPVVRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEAVHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALADGDGPEPPLRTVGEQQVVDEADRLIVNTDDEARQVISLHGADPARIDVVHPGVDLDVFRPGDRRAARAALGLPVDERVVAFVGRIQPLKAPDIVLRAAAKLPGVRIIVAGGPSGSGLASPDGLVRLADELGISARVTFLPPQSHTDLATLFRAADLVAVPSYSESFGLVAVEAQACGTPVVAAAVGGLPVAVRDGITGTLVSGHEVGQWADAIDHLLRLCAGPRGRVMSRAAARHAATFSWENTTDALLASYRRAIGEYNAERQRRGGEVISDLVAVGKPRHWTPRRGVGA
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol (MSH) biosynthesis pathway (By similarity).  MSH and WhiB3 are probably part of a regulatory circuit that mediates gene expression upon acid stress (like that found in host macrophage phagosomes).  MSH is one of the major redox buffers which protects bacteria against redox stressors and antibiotics; loss of MSH or ergothioneine (ERG, the other major redox buffer in this bacteria) leads to respiratory alterations and bioenergetic deficiencies that negatively impact virulence (By similarity).
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: RUVA_ECO5E
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: AAEB_SALDC
Sequence: MGIFSIANQHIRFAVKLACAIVLALFIGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGMLRIIGTFIGCIAALIIIISMIRAPLLMILVCCVWAGFCTWISSLVRIENSYAWGLSGYTALIIVITIQTEPLLTPQFALERCSEIVIGIGCAILADLLFSPRSIKQEVDRELDSLLVAQYQLMQLCIKHGDSEEVDNAWGDLVRRTAALEGMRSNLNMESSRWVRANRRLKALNTLSLTLITQSCETYLIQNTRPELITDTFRELFETPVETVQDVHRQLKRMRRVIVWTGERETPVTLYSWVGAATRYLLLKRGVISNTKISATEEEILQGEPVVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGNGAMVMIAVVTSLAMRLPNPRMVCIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCLSLAVLGFFIGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCMLAFIVILLVRDKSKDRTGRVLLNQFVSAAVSAMTTNVVRRKENRLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSVFHRQLRRTADHVISAGSDDKRRRYFGQLLDELDIYQEKLRIWEAPPQVTEPVKRLTGMLHKYQNALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARNT_SALEP
Sequence: MMKSIRYYLAFAAFIALYYVIPVNSRLLWQPDETRYAEISREMLASGDWIVPHFLGLRYFEKPIAGYWINSLGQWLFGATNFGVRAGAILTTLLAAALVAWLTFRLWRDKRTALLASVIFLSLFAVYSIGTYAVLDPMIALWLTAGMCCFWQGMQATTRTGKIGMFLLLGATCGLGVLTKGFLALAVPVVSVLPWVIVQKRWKDFLLYGWLAVLSCFVVVLPWAIAIARREADFWHYFFWVEHIQRFAMSDAQHKAPFWYYLPVLLAGSLPWLGLLPGALKLGWRERNGAFYLLGWTIMPLLFFSIAKGKLPTYVLSCFAPIAILMARFVLHNVKEGVAALRVNGGINLVFGIIGIVAAFVVSSWGPLKSPVWTHIETYKVFCVWGVFTVWAFVGWYSLCHSQQYLLPAFCPLGLALLFGFSIPDRVMESKQPQFFVEMTQAPLASSRYILADNVGVAAGLAWSLKRDDIMLYGHAGELRYGLSYPDVQDKFVKADDFNAWLNQHRQEGIITLVLSIAKDEDISALSLPPADNVDYQGRLVLIQYRPK
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSLO_SHEDO
Sequence: MSRDILHRYLFDNADVRGQLVQLEDSFQAMLAAQDYPKALQVLLGELMAATSLLTATIKFSGDISVQLQGDGPVSLAVINGNNELQLRGVARWKGELAKDASLPTLLGKGYMVITLTPDEGERYQGIVSLEHGTLAACLEEYFNQSEQLPTQIHLFATNAQAAGMLLQVLPSKQEQNDDFSHLSVLTQTIKPQELFDLGAEEVLHRLYHEEEVRLFEPMDVSFKCTCSRERSAGALKTLSLVELETILAEEGKIDMGCEYCTASYSFDAIDIAALFSDNADTSQTKTQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SH321_MOUSE
Sequence: MVQSELQLQPRAGRRADASNWGDFGSDKGGLGNTDIPPITPNSQRPPKLSNLTYDSPPDYLRTVSCPETCRVLFDYQPEAPDELALQKGDLVKVLRKTTEDKGWWEGECQGRRGVFPDNFVIPPPPIRKLIPRKIISRESAPIKETKKLMPKSSLPTVKKLAAAASAPGRAKTLSTPSGDSQKRPSRNSGFNGSCLNGGPRQPGRKGSRTQASQQHSASSQEDEQKSPGKGPSRSKTPTPEKTRLPDKVLAPETIPAPDKVSIPKDPVPKKAPDSDKIPATEDTTLDKAGTPESTLSGNKPAKDEALDLKMALHEDTAPALVKILTPEHMIFKKEPSRDNDQCQHLPQGGSTQRPESPAPSNNIQVPGEYSPPPDSSERSCCRVRQVNGSFPAQSKAEDVSAMEEANFLEEPLAKDERTLNKALPKKLPSERAGPQKQVLPQESAPTPQVPHTIQQMPVPEEAPTLHPLTPLTSPKSKNDRMDVLESLKEEVGLLRSRLELLELKLEQKMGDVWEELKTETLLSPEVQMMQRNRKSFKHAETQTETQTE
What are the official names of this protein?
SH3 domain-containing protein 21.
Protein: FABZ_BORPE
Sequence: MELDIKGIMDRLPHRYPMLLIDRVLEMVPGKSIVAIKNVSINEPFFTGHFPHHPVMPGVLIVEAMAQASALFSFTDENGGLKCDGAKTAYYLVGIDGARFRKPVVPGDQLRLEVEAERLSRTICKYQGRALVDGQLVAEAKLMCAIRSLEE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LIPA_AJECG
Sequence: MATSAGKLRTLYSAHSSLSSLPPSARPTLQLATLRSYATTTPHDSPIGNTSNTPPTVKRPATAFKDKLNAGPAFSDFVSGKKDEPLDPAEAYALKTALVGPPGRKKEITRLPPWLKTAIPDSSNYKRIKNDLRGLNLHTVCEEARCPNIADCWGGSSKSAATATIMLMGDTCTRGCRFCSVKTSNKPPPLDPHEPDNTAEALSRWGLGYVVLTSVDRDDLADGGARHFAETVMKIKQKAPNILVECLTGDYAGDLDMVALVANSGLDVFAHNVETVEALTPFVRDRRASFQQSLRVLKAAKAAKPELITKTSLMLGLGETEAQLWDALRALRAINVDVVTFGQYMRPTKRHMAVHEYVRPDVFDLWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRRGENAGSVNEKVTTSENVKKLVAGEAMM
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, mitochondrial, Lipoate synthase, LS, Lip-syn, Lipoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CPB2_CAEBR
Sequence: MSKSRRVFLSIQGDDDFWGNGDQLEGKTLSSIKQQESKKMDDSVEGMEEEKYFFRQSKLGRQNLERLHEKEEQECEEERLDWSEKVDSEEEEEDIQEQDEIITEGKETEMFDSGPETDQKMPVDPNEGFYNNYRSYFSGRPEMLFLIRSIDESATDYYEKPFIDLYETTRKRLEMYPNTELNQILRCACNPNAGGGADYRVRNKHAVVVSNFREPDRRLGRYSKYYYHHNVGPEVYSRKVFVGGLPACVKEMDILHFFSRYGRLQVDWPSKHYGCKSDSDPSVYNEPSFTPPTSHLGLSSPPFGQINPFMTDCPPAPSDLQMSRHGSVDGGGGGFPTHGMSMRNIGFGGGSGPRSTGEGEKKQQHLGYVFLLFEKERSVRDLVTECFEEEEGLFIILESAIEPIRVQIRPWLLADAEFLMDFNVPINTKMVAFIGGVPRPLKAVELAHFFEQTYGNVVCVGIDIDNKFKYPRGSGRVAFSNYHAYVQAITDRYIVLDHEDIHKRVEIKPYFFHNQSCEECSSRYHRQYAPFFCPSLECFQYYCEPCWHKMHARPSRFHHMPVVKGI
What is the function of this protein?
Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs.
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 2.
Protein: AROQ_DESHD
Sequence: MGKIWVLHGPNLNLLGRREPDKYGTQTLDEINNELLHKAYTAGIPIQVEQTNFEGELIQWIHSMGPDDFLIINPGAWTHYSYAVRDAITSVQVPAIEVHLSNIHAREEFRKTSVIAPVCCGQISGLGGKSYSLALDYALEALTQK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: AQY1_YEAS7
Sequence: MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISKDTLRNHFIAAAGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKGETSSSSAVAEV
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes.  Involved in sporulation, freeze tolerance and osmotolerance.  Is non-functional in most laboratory strains.
What are the official names of this protein?
Aquaporin-1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: OTC_LISMH
Sequence: MTMYAKNNTAGKDMLSLLEWNKEELTDIIKLAVAMKTNPAHYSHILSGKILGMIFDKPSTRTRVSFEAGILQLGGQAIVMSSKELQIGRGEPIKDTAHVMSEYIDAIMIRTFSHEKVEELAYHAEIPIINGLTDLHHPCQALADLMTIYEWKDQLEGVKLAYIGDGNNVCHSLLLAGAMVGLDIRLAMPKGYEVDETILATAENLAKESGAKIFVTVDPKHAVADADFIYTDVWTSMGQEEENAKRLADFGEKYQVNAELASVAKPDYHFLHCLPAHREEEVTAEIIDGNHSVIYQQAGNRLHAQKALLAAILEAK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.