PharMolix/UniProtQA huggingface dataset:
Protein: ZTF1_CAEEL
Sequence: MSEALETGDPSPPPPIVSENGKTYYYLNSQESQAPNTPSPQEVPPKKMTNLFESGPLVYEDVAADIEAVTERASRRHYENKMVVKNSREMFDNVNILPDGRYYCCLCNRPYKTHATLTAHLRGYHLRNESSCDEPGCNFLSFTDQEKKRHRRTHDKKKKERNSQESMVIHEKIQKAVRRLDYPGEDELRDHLNGSTEVQGTIRTMTKKGKIRYACLKCPHSVFNAYHAARHVEMHNDFPKNCFYCGEIRKGTVDLQVHYMRVHKHEGIRTFKCSVCHLRFTTTILFRDHVECENGCQNPEIRQDIYYGELPEGTIVDDLTQDRLQNFRKRQEIWKTMGQMVEEHRTDVHEEIVGESSVQAGDTTVFDGSRAFIQTPFGLKTALEVKNTSRFCPRSGKRTSDDDLMITNKKRERLEMAPNLHFHQDIIHRLPTSTTTQRQNNAFQNEYLRPPVSYGYDPLIGRYPDFQLMSQSSLPSSSASSSSYDPFATAVYQDSDRNPMQPNDQHICDMNNVGAYETANFGLDNSSDLVVNEATIASNLMVNEVEDEVFEELNKLDFVMPADDGNDNDDDLEEVFNFGNVA
What are the official names of this protein?
Zinc finger transcription factor family protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENV_HV2SB
Sequence: MSGKIQLLVAFLLTSACLIYCTKYVTVFYGVPVWKNASIPLFCATKNRDTWGTIQCLPDNDDYQEIPLNVTEAFDAWDNIVTEQAVEDVWNLFETSIKPCVKLTPLCVTMNCNASTESAVATTSPSGPDMINDTDPCIQLNNCSGLREEDMVECQFNMTGLELDKKKQYSETWYSKDVVCESDNSTDRKRCYMNHCNTSVITESCDKHYWDAMRFRYCAPPGFVLLRCNDTNYSGFEPNCSKVVASTCTRMMETQPSTWLGFNGTRAENRTYIYWHGRDNRTIISLNKYYNLTILCRRPENKTVVPITLMSGRRFHSQKIINKKPRQAWCRFKGEWREAMQEVKQTLVKHPRYKGTNDTNKINFTAPEKDSDPEVAYMWTNCRGEFLYCNMTWFLNWVENKTGQQHNYVPCHIEQIINTWHKVGKNVYLPPREGELSCESTVTSIIANIDVDGDNRTNITFSAEVAELYRLELGDYKLVEVTPIGFAPTAEKRYSSAPGRHKRGVLVLGFLGFLTTAGAAMGAASLTLSAQSRTLFRGIVQQQQQLLDVVKRQQEMLRLTVWGTKNLQARVTAIEKYLADQARLNSWGCAFRQVCHTTVPWVNDTLTPEWNNMTWQEWEHKIRFLEANISESLEQAQIQQEKNMYELQKLNSWDVFGNWFDLTSWIKYIQYGVMIVVGIVALRIVIYVVQMLSRLRKGYRPVFSSPPGYIQQIHIHKDWEQPDREETEEDVGNDVGSRSWPWPIEYIHFLIRLLIRLLTRLYNSCRDLLSRLYLILQPLRDWLRLKAAYLQYGCEWIQEAFQALARVTRETLTSAGRSLWGALGRIGRGILAVPRRIRQGAEIALL
What is the function of this protein?
The gp120-gp41 heterodimer allows rapid transcytosis of the virus through CD4 negative cells such as simple epithelial monolayers of the intestinal, rectal and endocervical epithelial barriers.  Both gp120 and gp41 specifically recognize glycosphingolipids galactosyl-ceramide (GalCer) or 3' sulfo-galactosyl-ceramide (GalS) present in the lipid rafts structures of epithelial cells.  Binding to these alternative receptors allows the rapid transcytosis of the virus through the epithelial cells.  This transcytotic vesicle-mediated transport of virions from the apical side to the basolateral side of the epithelial cells does not involve infection of the cells themselves (By similarity).
What are the official names of this protein?
Envelope glycoprotein gp160, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein gp41]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Note=It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag. SUBCELLULAR LOCATION: [Surface protein gp120]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Host endosome membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the extravirion surface through its binding to TM. It is probably concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity).
Protein: UVRC_CLOB1
Sequence: MFDLEYQLKNLPDKPGVYLMKNNLGEIIYVGKAKILKNRVRQYFQKSQKHSEKVKAMVKNIEEFEYIITDSEIEALILECNLIKKYRPKYNILLKDDKHYPFIKVTLAEDFPRVISTRKVTKDGSKYFGPYVDGSSVKDIIELIKKTFPIRTCKKNIVEEAKAIRPCLNYQIGLCKAPCAQYIKKSEYRETIDDVIKLLSGKHLDIVENFKLNMEKAAENLEFEKAAMLRDKINIIEKIGEKQKIILNNFDNEDYISLYSDGKDTCFQVFFLRNGKIVGREHFIIEDTFDTNSSTLISNFLKEFYGGTAYIPKTIYVPNIEDEALLEQWLTLKKESKSTIKIPIKGEKKNILVLVEKNAKTTLENFKLKYLQEKALYDNVLKDLKNILRLQEEPIRIEAFDISNIQGFDSVGSMVVFEKGRAKPSDYRRFKINTVKGADDYKSMKEILTRRFQHGLSEIKSIQDRKLEFSSGKFSVFPDLILMDGGKGQINIALEVLNAFNIDIPVCGMVKDNKHRTRGLIYNGEEIIINKYGSVMKFITRVQDEVHRFAISYHRSLRGKNSFHSLLDDIPNIGEKRKKDLLFNFKSIDNIKKATYEELLSIPSMDKKSAECVLEFFK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_SALPK
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: ENPL_CATRO
Sequence: MRKWTVPSVLFLLCPSLSSSCQGRKIHANAEADSDAPVDPPKVEDKIGAVPNGLSTDSDVAKREAESMSMRNLRSDAEKFEFQAEVSRLMDIIINSLYSNKDIFLRELISNASDALDKIRFLALTDKEILGEGDTAKLEIQIKLDKEKKILSIRDRGIGMTKEDLIKNLGTIAKSGTSAFVEKMQTSGDLNLIGQFGVGFYSVYLVPDYVEVISKHNDDKQYIWESKADGAFAISEDVWNEPLGRGTEIRLHLRDEAQEYLDEFKLKELVKRYSEFINFPIYLWASKEVEVEVPAEEDDSSDDEDNKSESSSSEEGEEEETEKEEDEKKPKTKKVKETTYEWELLNDMKAIWLRNPKDVTDDEYTKFYHSLAKDFSEEKPLAWSHFTAEGDVEFKAFTLLPPKAPQDLYESYYNSNKSNLKLYVRRVFISDEFDELLPKYLNFLKGLVDSDTLPLNVSREMLQQHSSLKTIKKKLIRKALDMIRKIADEDPDEANDKDKKEVEESTDNDEKKGQYAKFWNEFGKSIKLGIIEDAANRNRLAKLLRFESTKSEGKLTSLDQYISRMKSGQKDIFYITGTSKEQLEKSPFLERLTKKNYEVILFTDPVDEYLMQYLMDYEDKKFQNVSKEGLKIGKDSKDKELKESFKELTKWWKGALASENVDDVKISNRLANTPCVVVTSKYGWSSNMERIMQSQTLSDASKQAYMRGKRVLEINPRHPIIKELRERVVKDAEDESVKQTARLMYQTALMESGFMLNDPKEFASSIYDSVKSSLKISPDATVEEEDDTEEAEAESGTTESSAAEDAGAETLDLKDEL
What is the function of this protein?
May have a molecular chaperone role in the processing of secreted materials.
What are the official names of this protein?
Endoplasmin homolog, Glucose-regulated protein 94 homolog, GRP-94 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: SSL11_STAA8
Sequence: MKLKNIAKASLALGILTTGMITTTAQPVKASTLEVRSQATQDLSEYYNRPFFEYTNQSGYKEEGKVTFTPNYQLIDVTLTGNEKQNFGEDISNVDIFVVRENSDRSGNTASIGGITKTNGSNYIDKVKDVNLIITKNIDSVTSTSTSSTYTINKEEISLKELDFKLRKHLIDKHNLYKTEPKDSKIRITMKDGGFYTFELNKKLQTHRMGDVIDGRNIEKIEVNL
What is the function of this protein?
Secreted protein that plays a role in the inhibition of host immune system.  Targets myeloid cells such as monocytes or granulocytes through binding with sialyllactosamine-containing glycoproteins.  Prevents initial rolling of neutrophils toward the site of infection by interacting with host SELPLG.  Disrupts neutrophil motility by induction of cell adhesion via interacting with glycans but independently of SELPLG.
What are the official names of this protein?
Staphylococcal superantigen-like 11.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal/streptococcal toxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TM236_RABIT
Sequence: MASGRLIKLVIFELLEFAAFSIPTLVIMEQFATAYQRTRNASEKTHYWLIVSCSIAYVAVVSLLIWVPVKVLLHKKRHLYKKIKGWRPVMMMCVVLTTLPSFIFSIAVTEVQKTINTTVDVLPDTLPDLPVSLVISSLIITDIIEKLRFHPIRGYQKSNEDKHIHTSSLQQVRTVTEQVRQNGENAASPCAASPSETWQPPGALTHSAVPMFAGPQEPFFGSGILKTMSRRDVRAEIFLWSFLLWSDTIEMVRVAGHPNVYKTNWLYPVYLFSFISLLRIIFTPQNPLLSCLGILLQDLPFVFVRLSLIIALGTITPVLGLCKNVLVTLSYVYFNFLTRFRAFSNFELSPF
What are the official names of this protein?
Transmembrane protein 236, Brush border protein AdRab-C.
What is the protein family that this protein belongs to?
Belongs to the TMEM236 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS2_HALH5
Sequence: MNVDDLTFDDKGLIPAVVQDAQSKEVVTVAYMNRESFEKTVETGETWFYSRSRQELWHKGATSGHTQKVVDIRYDCDGDALVVLVELKGPACHTGKYSCFFESVFGKKIYGASDRFGIIATLEALIAEREAEMPEGAYTTYLFEKGVDKILKKVGEEATEVVIAAKNRDAEELKWEVADLLYHLLVLLREQKLPVDEVLAVLEERHRPKEE
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
Protein: TAL_ACIAC
Sequence: MNQLDALKQVTTVVADTGDFRQLGAYRPQDATTNPSLILKAVQKADYAPLLQESVERWRGRALDEIMDRLIVRFGCEILSLIPGRVSTEVDARLSFDTMATVTRGERIIDLYRAEGVDTARVLIKIAATWEGIEAARILEERGIHTNLTLLFSPVQAVACGAARVQLISPFVGRIYDWYKKQAGAQWDEAAMAGANDPGVQSVRQIYQYYKHFGIRTEVMGASFRNIGQITALAGCDLLTIAPELLAQLAASEAPLERALDPASAKDLELQPVQYDEPGFRYALNADAMATEKLAEGIRAFAADAAKLEQMVLAA
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMF16_NEPOL
Sequence: MNFVISQHFNEIKYRFLYIFFTFLLCFIICTIYSESIMFFYVHPLINLTSMQGKHLIFTEMSEAFHTYIFLCFFTSIYCTFPYFFYQFWAFFIPSTYQFERLQLRFLSFFFFTLLFFSCIIIYFIILPEIWSFFLHFEKKSYYFNLQLEARISSYIQFTFQIFSYFFVLFQCPLFTHFSLNLNLLTISFLVNSRKYIYFLFLILAAFLSPPDILSQFFLFSLIVFMYELCVFYSCFYDSLRERIKTF
What are the official names of this protein?
Uncharacterized tatC-like protein ymf16.
What is the protein family that this protein belongs to?
Belongs to the TatC family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: OPPC_MYCGE
Sequence: MDRNKSFDPNLFKRVDINLLKRNDQLIGKPTTNSIEIIKRLFQNKWAILFFLLIVVIVLLAIIVPLTSPFSAVTPVSTNALAQNLPPRYLWHKPGDILVHKITARSIAEISQASGVLVGTLPSANSNPLATNVQYDIAPFQLQELRNYFPLLGTNGLGIDIWTLLWASVAKSLWIAVVVAIIAMVFGTIYGAVAGSFVGHMADNIMSRIIEIIDIVPSILWIIVLGATFRFGGVKQFDDSVVIFTLIFVFWTWPATTTRIYILKNKDTEYIQAAKTLGAHQIRIIFVHMLPVVFGRLAVVFVSLIPAVIGYEASLVFLGLKPATDIGLGALLNQVTSSDNVALILSSIVSFAVLTVAARTFANALNDAIDPRVVKR
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Oligopeptide transport system permease protein OppC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. OppBC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDR3_CANAX
Sequence: MAKTSQAEGQPYKGYYNNKSQGQPYHGYYSGFNKSASAQIHHLARSLTQGVQSHYDDTYTTATMHPNGINPISDKTDPTLDPESPSFSSKRWVQNMWKLYQSDSEYYKPGKLGVAYKNLRVYGDAIESDYQTTVSNGVLKYARNIFNKFRKDNDDYSFDILKPMEGLIKPGEVTVVLGRPGAGCSTFLKTIACRTEGFHVADGSVISYDGITQDEIRNHLRGEVVYCAETETHFPNLTVGETLEFAALMKTPQNRPMGVSREEYAKHVVDVVMATYGLSHTKNTKVGNDFIRGISGGERKRLSIAEVTLVQASIQCWDNSTRGLDAATALEFISSLKTSASILNDTPLIAIYQCSQNAYDLFDKVIVMYEGYQIFFGSSQRAAAYFKKMGFVCQDRQTTPDFLTSITSPAERIIKPGYERLVPRTPKEFYRYWRRSPERQALLEEIDEYLDNCENYDQKQKIFEANNAKKAKHTYNKSSYTVSLPMQVRYIMKRYWDRMRGDIIVPLSTVAGNIAMALILSSVFYNLQPNSSSFYYRTSVMYYALLFNAYSSVLEIYNMYEGRAIVQKHREYALYPPMADAIGSIISDFPLKVVCSVLFNLILYFMVNFKREPGAFFFYLLISFCSTLFMSHLFRTIGAFTNSLAEAMTPSSLLLFALSTFSGFAIPVTYMLGWCKWIRWVNPLAYAYEALISNEFHGRVFDCSNIVPSGFGYPKTGNSVVCASIGALPGEFKVDGDLYLKLAFDYSYSNVWRNFGVLMAFIIFLFGTTIFFVQTNKSSISKGETLVFRRKNIRKMRKMEEDEEAYMDGMAPLDFSGSTEISDYSYDYMDRKLLDTSNIFHWRNLTYTVKIKSEERVILNNIDGWVKPGEVTALMGASGAGKTTLLNALSERLTTGVITSGTRMVNGGELDSSFQRSIGYVQQQDLHLETSTVREALKFSARLRQPNSVSIAEKDSYVEKIIDLLEMRTYVDAIVGVPGEGLNVEQRKRLTIAVELVARPKLLVFLDEPTSGLDSQTAWSICKLIRKLANHGQAILCTIHQPSAILLEEFDRLLLLQKGETVYFGEFGANCHTLIEYFERNGASKCPQHANPAEWMLGVIGAAPGTQANQDYFETWRNSPEYRAVQNELHRLEEMPGLASGEKEPDTNQAYAASFWKQYIFVVHRLFQQYWRTPSYIYSKFAMAVLCSLFNGFTYYKSQNSMQGLKNQMLSIFSMFVVLTTLAQQYVPLFVTQRDLYEARERPSKTFSWLAFIAAQITAEIPYQVLAATISFFSWYYPVGLYRNAVYSGAVTHRGVLMWLIMTLMFIYSSTLAQFCISWNQLADYAANWISLLLTISMIFCGVIATKDSMPKFWVFLYRCTPLTYLTSAMMSIGLGDSFVKCAPTEILTFPPQTPGVQKCQDYMGAYISIAGGYLLNPEATDNCKFCIMDKTNQFLDFMNISIHNFGRDTGIFIVFIVFNMAATVFSYWLFRVPKGNREKGSFFDKLPFLNGGGDTNHENV
What are the official names of this protein?
Opaque-specific ABC transporter CDR3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PURR_SALTI
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLSMLEEYRHIPMVVMDWGEAKADFTDTVIDNAFAGGYMAGRYLVERGHRDIGVIPGPLERNTGAGRLAGFMKAMEEALINVPDNWIVQGDFEPESGYHAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSVIGYDNVRNARFFTPALTTIHQPKDSLGETAFNMLLDRIVNKREESQSIEVHPRLVERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: NADD_SHEAM
Sequence: MTKQPNAKRHTALLGGTFDPPHFGHIRPLLDVLKHWPLQDCWLLPNHIPPHKPGTHASPKARLEMIDALCREFPAFSLCDVELRRDEPSYTVNTLRQLRELYPDRVFYFVMGMDSFLSLDKWFEWQQLFELCHLVVCARPGYQLAADHGMAEVLANRQHTEADLPAEDSGKVLIADIREQDISSTDIRTALAERRDIRQLVPESVARVIETQGLYR
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: IF1_HELHP
Sequence: MAKDDVIEVDGKVIEALPNATFRVQLENGHIVLCHIAGKMRMHYIKILPGDMVKIELTPYSLDKGRITYRHK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_HAMD5
Sequence: MMNEDGAYSKKDLEASSRGELFGPKGPRLPASNMLMIDRVITMTKDGGMHGKGYVEAELDVHPNLWFFGCHFIDDPVMPGCLGLDAMWQLVGFYLGWLENEGKGRALGVGEVKFKGQVLPDSKKITYCIDFKKVITGKLIMGIADGKVLSDGQQIYTADDLKVGLFKNTSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_SALPB
Sequence: MARHPRWTLSQVTELFEKPLLELLFEAQQIHRQHFDPQQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLDSARKAKNAGSTRFCMGAAWRNPHERDMPYLEKIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVTDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMTPDTDDYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: GXLT1_CHICK
Sequence: MRRFARVALLFLGCGVCSLLYGVSQLALSLEQEAGGARQRQARESAAPGGGRQAGSADGGEEGAGRCKNLSVSFWNSYWMLPSDVCGVNCFWEAAFRYTYMETQPSETMHLAVVACGERLEETITMLRSAIIFSIKPLHFHIFAEDQLHESFKDILDDFPYEGKVNYTLYPITFPSEGAKEWKKLFKPCASQRLFLPLILKDVDSLLYVDTDILFLRPVDDIWSFLRKFDSTQIAAMAPEHEEPRIGWYNRFARHPYYGVTGINSGVMLMNMTRIRRKYFKNDMTSVRLRWAEILMPLLKKYKLNITWGDQDLLNIMFFHNPESLYVFPCQWNYRPDHCIYGSNCKEAEEEGIFILHGNRGVYHDDKQPTFRAVYEAIKNYSFGDDLVRSLLQPLELELQKTVHTYCGRVYEVFIKQLKKSIKDLSVRRSKGS
What is the function of this protein?
Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.
What are the official names of this protein?
Glucoside xylosyltransferase 1, Glycosyltransferase 8 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: SYP_BIFA0
Sequence: MSTLFLRTLREDPADADVDSAKLLQRAGYIRKAAPGIWTWLPLGLAVLNKIEDVIREEINGIGAQEVHFPALLPREPYEATHRWEEYGDNIFRLKDRHEADYLLAPTHEEMFTLLVKDMYSSYKDLPVTLYQIQTKYRDEFRPRAGLIRGREFIMKDAYSFTVDEEGMRQAYMDERGAYERIFQRLDLKYVPVFAMSGPMGGSASEEFLAPMPIGEDTFALAPSGKAWNVEALHTPAVEAVDCSQTPDATKRATPNARTIDEMIAFANAEYPREDGRDWQASDILKNVVIAVKHAEDDEHDEPWRELVVVGIPGDRTIDMKRLEAQFAPAELEEATEDDLKAHPELVRGYIGPMGFGPQARGDDGTAETLRYLIDAHVAEGSAWFTGADEEGVDYYDLVYGRDFKADDVVEAVQVRDGDMSPDGSGPLSFERGVEIGQVFQLGLKYSEALDLKVLNQNGKTVPVWMGCYGIGVSRVLACIAETHHDDKGLAWPMNIAPAQVHVMATGKDEAAFEAAERLVDELSANGIEVLYDDRRKVSPGVKFKDAELIGVPIIAVAGRDTVNNGTIEVRDRDGSNSENISVDSVAQVIVDRVHEALK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLU7_YEAST
Sequence: MNNNSRNNENRSTINRNKRQLQQAKEKNENIHIPRYIRNQPWYYKDTPKEQEGKKPGNDDTSTAEGGEKSDYLVHHRQKAKGGALDIDNNSEPKIGMGIKDEFKLIRPQKMSVRDSHSLSFCRNCGEAGHKEKDCMEKPRKMQKLVPDLNSQKNNGTVLVRATDDDWDSRKDRWYGYSGKEYNELISKWERDKRNKIKGKDKSQTDETLWDTDEEIELMKLELYKDSVGSLKKDDADNSQLYRTSTRLREDKAAYLNDINSTESNYDPKSRLYKTETLGAVDEKSKMFRRHLTGEGLKLNELNQFARSHAKEMGIRDEIEDKEKVQHVLVANPTKYEYLKKKREQEETKQPKIVSIGDLEARKVDGTKQSEEQRNHLKDLYG
What is the function of this protein?
Essential protein involved in the second catalytic step of pre-mRNA splicing.  Involved in the selection of 3'-type splice sites; this selection could be done via a 3'-splice site-binding factor, PRP16.
What are the official names of this protein?
Pre-mRNA-splicing factor SLU7, Synthetic lethal with U2 snRNA protein 17, Synthetic lethal with U5 snRNA protein 7.
What is the protein family that this protein belongs to?
Belongs to the SLU7 family.
Protein: TPPP3_XENTR
Sequence: MAENSDLTSLEESFRKFAIYGDTKATGQEMTGKNWAKLCKDCKVIDGKSVTGTDVDIVFSKVKGKSARVITCEEFKKALEELSGKRFKGKSKEEAYEAICKLVVGKEPVSAGITKPAATGAVDRLTDTSKYTGSHKERFDESGKGKGKGGRETIVENTGYVSSYKLAGTYDAKVKK
What is the function of this protein?
Regulator of microtubule dynamic that has microtubule bundling activity.
What are the official names of this protein?
Tubulin polymerization-promoting protein family member 3.
What is the protein family that this protein belongs to?
Belongs to the TPPP family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.
Protein: RL9_ANAMF
Sequence: MLSVILKSSVRGLGKAGEIAKVRPGYARYLLADGKAVRATKDNVALLEQKLALIEEENSKKLAEAEGVAKSLGAERLIIVRQSSDDGKLFGSVTVRDVSKLLCDLGYDIQPRCVSFSEVIKRTGEYEINVELHADLVATLRLHVVRNESEAERVRLGIAKSEDQAAAAAEVEQAEDVAAAEQQDSSPVDDHADDADGVADGEGRDEGAGDASDEEEMPST
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: RS13_SULNB
Sequence: MARIAGVDLPQKKRIEYALTYIYGIGLTTSRKILDRTGIDYNTRVHELTDAQAATIRNDIQENVMVEGDLRKKVTLDIKALMDLGSYRGLRHRRGLPCRGQKTKTNARTRKGKRKTVGAA
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: Y1451_LACGA
Sequence: MVNIYDNANQMAKDLQETEQFKDLKKSLENLKNKPESLDLYQRMDKLQQQILAAQNSGQPLSDDVKKEYQKINEEVRNNDELKDMITKEQALFQMINDVQQAMTKPIGDLYDDLKAK
What are the official names of this protein?
UPF0342 protein LGAS_1451.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: CGGR_BACSU
Sequence: MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLSASLGISERVLRGEVQFLKEQNLVDIKTNGMTLTEEGYELLSVLEDTMKDVLGLTLLEKTLKERLNLKDAIIVSGDSDQSPWVKKEMGRAAVACMKKRFSGKNIVAVTGGTTIEAVAEMMTPDSKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEPSVKEVLNTIKSASMLVHGIGEAKTMAQRRNTPLEDLKKIDDNDAVTEAFGYYFNADGEVVHKVHSVGMQLDDIDAIPDIIAVAGGSSKAEAIEAYFKKPRNTVLVTDEGAAKKLLRDE
What is the function of this protein?
In the absence of glucose, represses the transcription of the gapA operon, which encodes five key glycolytic enzymes.  Binds specifically to the cggR-gapA promoter region and blocks the progression of the RNA polymerase, leading to the arrest of the transcription.
What are the official names of this protein?
Central glycolytic genes regulator.
What is the protein family that this protein belongs to?
Belongs to the SorC transcriptional regulatory family.
Protein: NUDI_SALPB
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRIKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.