PharMolix/UniProtQA huggingface dataset:
Protein: CNN1_MELGA
Sequence: NRGPAYGLSAEVKNKLAQKYDPQTERQLRVWIEGATGRRIGDNFXDGLKDGVILMELINKLQPGSVQKVNDPVQNWHKLENIGNFLRAIKHYGVKPHDIFEANDLFENTNHTQVQSTLIALASQAKTKGNNVGLGVKYAEKQQRRFQPEKLREGRNIIGLQMGTNKFASQQGMTAY
What is the function of this protein?
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction.  It is capable of binding to actin, calmodulin and tropomyosin.  The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
What are the official names of this protein?
Calponin-1, Calponin, smooth muscle.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: COQ8A_MOUSE
Sequence: MAAMLGDAIMVAKGLAKLTQAAVETHLQNLGLGGELLLAARALQSTAVEQFSMVFGKVQGQDKHEDSYATENFEDLEAEVQFSTPQAAGTSLDFSAASSLDQSLSPSHSQGPAPAYASSGPFREAGLPGQATSPMGRVNGRLFVDHRDLFLANGIQRRSFHQDQSSVGGLTAEDIEKARQAKARPESKPHKQMLSERARERKVPVTRIGRLANFGGLAVGLGIGALAEVAKKSLRSENSTGKKAVLDSSPFLSEANAERIVSTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMTKTLNSDLGPHWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNLMAVLNMSNMLPEGLFPEHLIDVLRRELTLECDYQREAAYAKKFRELLKDHPFFYVPEIVDELCSPHVLTTELISGFPLDQAEGLSQEVRNEICYNILVLCLRELFEFHVMQTDPNWSNFFYDPQQHKVALLDFGATREYDRSFTDLYIQVIRAAADQDREAVLKKSIEMKFLTGYEVKAMEDAHLDAILILGEAFASEEPFDFGTQSTTEKIHNLIPVMLKHRLIPPPEETYSLHRKMGGSFLICSKLKARFPCKAMFEEAYSNYCRMKSGLQ
What is the function of this protein?
Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294).  Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294).  Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity).  Shows an unusual selectivity for binding ADP over ATP (By similarity).
What are the official names of this protein?
Atypical kinase COQ8A, mitochondrial, Chaperone activity of bc1 complex-like, Chaperone-ABC1-like, Coenzyme Q protein 8A, aarF domain-containing protein kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. ADCK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single-pass membrane protein.
Protein: Y643_STRP6
Sequence: MSQEIYDYANQLERAVRALPEYQKVLEVKEAIQADASASQLFDEFVAMQEKIQGMMQSGQMPTAEEQTSIQELSQKIEANDQLKAYFEAQQALSVYMSDIERIVFAPLKDLVK
What are the official names of this protein?
UPF0342 protein M6_Spy0643.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: YGI3_SCHPO
Sequence: MSNGEFIDQYLLPESGAILQDYLDDYFYTSWYTGNRNLIQLDHYGFPTASNFELNPKSTDNCGTVDFQGIPWGNKAIGKRKNFRLYRLHTYSLSCNHSDWSPEELSLDTVQVAAEDSFYEFQRFLKNPNCLRNHHHLCKSVKVVGEHSVIYVSNNSIRMENTLHDNSVQIIDLKNNILQKKAISCLDTTNAVGCLGTLYGQYCIFNFKNGSFSTRKLSDDSINHIQLFSEKKFILGCNDGAVYVEDVQRTSPILVYRCSNAVNCVQLFDETPLALVCTDSKDAMLIDIRSNSVSAKLPHSDSVLTGSWHPNGNILATGGQDTTAKVWDIRALGKSFRNLGSQMSAVTNLCFSPLGESLAVTEQADFVQLFDTKLFNTSQVIDFFGEIAGTAYSSSGDSLFIGVDDPMLGGILEFRRPLQHPLSFIF
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C2A9.03.
Protein: GLY2_CAEEL
Sequence: MRRRHRCVALLFIFSAFITPLGFFYYTISNESKRYSEESEKNYGYQTLEFTESPEEISVDFDKYSQSECSRFPSNVEIEYPECLNKMKWIKNGWKTHHCYIENHIDGSECSFRYYLSQVENYCPPMEHHGKRKGLAKISPSIRRLLPIFESIPHYMKTRINRLWKKWKEGAHEVMQKYPKSMIERRKLNVLVFIGFLANEQKLNMAKKSDHGGPLGELLQWSDLLATLSVIGHHLEVSTNKNTLRNIVWKYMSRGPCQYVNNFRQQLDIIFTDIMGFNILRQHHRQFLLSNRCRIRLLDSFGTHAEFTTKTYFVQNKKSLSGPFSQRNPWGGHGLDLRQHWTFYPHSDDNTFLGFVVDTEGIDKKNNQMIPSALVYGKEQYMWRDAEKPIDVLKRIVTVHSTVADLDLKDSNISSIFKKVQNHGFLNSEEISQLLDNITIFFGLGFPLEGPAPLEAMAHGAVFINAKFKEPKSRLNYKFLAEKPTLRKWTSQNPYMEKIGEPHVITVDIFNELELEEAIKRAISLKPKHFVPFEFTPAGMLHRVALLLEKQELCDKIAYSKRWPPIDQMKIFRTLNADDSCETICHSKQLLCEPSYFPIINSSPLLRRENLCSSTTSDSSPFAPFNCTIQQSAFLFSCASSPPISFEINRLCPCRDYIPEQHAICKKCL
What is the function of this protein?
Catalyzes the addition of N-acetylglucosamine (GlcNAc) in beta 1-6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides.
What are the official names of this protein?
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase, GlcNAc-TV, Glycosylation-related protein 2, N-acetylglucosaminyltransferase gly-2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 18 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: UTS2B_MOUSE
Sequence: MKVFSTSLWCGLLTLLSVMNLFKSVRGRPHLSSGHELFPAKEHAAQEKLTRNPGLQRPFHAGGDLPSKLEELRQVKKLRDWIMEAKNTGLSNALDNLSSSHTKKRACFWKYCV
What is the function of this protein?
Potent vasoconstrictor.
What are the official names of this protein?
Urotensin-2B, Urotensin II-related peptide, Urotensin IIB, U-IIB, UIIB, Urotensin-2 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the urotensin-2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMN6_YERPP
Sequence: MGEQLKKQPVLRGGGFTFKQFFVAHDRCAMKVGTDGVLLGAWVPVLHARRVLDIGCGSGLIALMIAQRSLPQVQIDGVELEPAAAQQASSNVELSPWAERIHIHQQDIHQFAENHPHQYDLIVSNPPYFAPAIACRDEARDTARYTGSLTHDALLNCAEKLITEDGMFCVVLPHELGIEFARLAGQQGWFVRCQVDIRDRPGKPLHRMLLTLSRQAGETVYQHLALRQSEGVYSPEFCQLISDFYLNY
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_PHOPR
Sequence: MTKSELIERLCSQQTHLSAKQVEDAIKEILEHMAGTLAEGDRIEIRGFGSFSLHYRAPRVGRNPKTGDKVELDGKYVPHFKPGKELRDRVNAAIAA
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: PRMG_RHOJR
Sequence: MAKELRYNTDARARLEHGVNALADAVKVTLGPKGRNAVLEKLTGPPTITNDGVTIAREIQLREPFANMGAQLVKEVAMKTNGVVGDGTTTATVLAQAMVREGLRSVDAGANPMRVRRGIERAVSVVVDSLHEQASQIGGQSDLQRIATLAASDDEVIGHAISKAVDYVGKSGVVTTEESDTLGLSVDIVDGIEFDHGYISGYMVTDPERMEAVHTNPLILLTNKKITQVQDIMPSIEVAKRADRPLVVLAEEVDGPALQLLVGGNMHKTMQSVVVRAPGFGHRRVAELEDLAVALGGHVIAKDTGIELSEISVEHLGSCDRITVTENETTIVGGHGDQRLLDARIAQLESQHERAKIEADQESLELRIARLTGRVAVIRVGGATSVELKERMLRVEDALAATRAAVEAGIVSGGGTALAQSHRALADLDLTGDEAIGCDVVRRALAEPLRWIAINAGFDGDEVVEVVAGLPLGHGFNALTGEYGDMFDDGVIDPFKVTRAALESAASIAALLITTETAVVEEVLGNPGAIMAPGFGDLAEGMVRPSNIY
What is the function of this protein?
Probably plays an essential role in the productive folding of PrmA, and thus in the formation of the active PrmABCD complex.
What are the official names of this protein?
Probable chaperonin-like protein PrmG.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
Protein: PEPB_PECAS
Sequence: MTNNTMLISLSTQPADARWGEKATLSVNEQGFTIHVGTTSLNGKAALATIQRAARKIDGQGIKHVTLAGEGWDLANSWAFWQGYRGPKGQRTVEWAELNDADKKELNDRLKIVDWVRDTINLPAEDLGPEQLATRAVDLLCDVACDAVNYRITKGEDLREQNYAGLYTVGRGSERQPVLLALDYNPTGNPDAPVFACLVGKGITFDTGGYSLKPSGSMDSMKSDMGGAATLTGALALAASRGLQQRVKLYLCCADNMVSGNAFRLGDIIRYRNGKTVEVMNTDAEGRLVLADGLIDASEQNPQWIIDCATLTGAAKMALGNDYHALFSFDDELVAALQESAKEENEPFWRLPLEEFHRSHLPSSFADLNNIASGAHTAGASTAAAFLSHFVKNYQQGWLHIDCSATYRKGAVDQWATGATGLGVRTLANLLLSNAK
What is the function of this protein?
Probably plays an important role in intracellular peptide degradation.
What are the official names of this protein?
Peptidase B, Aminopeptidase B.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHSE_SULTO
Sequence: MIVKAFSSSANLGAGYDILALAHDAFEDTIEIYAQNSSELDIKVEGNGVPLSIDKNSASFALLELLRSYDIKAKIRLKIIKGIPAGLGLGSSGASAAAAVYAANEIFKLNLSRQELVNFAMKGEIASSGSPHPDNVAASLVGGLVSVLNSNPVKVEQVPLNLEFQIILIIPFVRIEAKTKKAREMVPKQIDTSKYVTNARYLSSLLLGFIKGDRELVRLGLNDEIIEKAREPLFPHYPKIKEISLLYDAIGACVSGAGPTIAIFVDSKSDKNKILGESLNVCKAYGYECTYKIAKVSGGAWVERRD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_MYCBO
Sequence: MVAVEQSEASRLGPVFDSCRANNRAALIGYLPTGYPDVPASVAAMTALVESGCDIIEVGVPYSDPGMDGPTIARATEAALRGGVRVRDTLAAVEAISIAGGRAVVMTYWNPVLRYGVDAFARDLAAAGGLGLITPDLIPDEAQQWLAASEEHRLDRIFLVAPSSTPERLAATVEASRGFVYAASTMGVTGARDAVSQAAPELVGRVKAVSDIPVGVGLGVRSRAQAAQIAQYADGVIVGSALVTALTEGLPRLRALTGELAAGVRLGMSA
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: VHUD_METVO
Sequence: MAEPIIMAFICYQCGYGAADLAGTSRMQYPASVRPIRVPCTGKFLYYLRIKGIPKGADAVFVAGCKPNECAFETGNFSVEERVKMTKQILDEMGIGGDRIEMFFMSGADAGKFTEAVNEMTDRAKKLGPNPLKK
What are the official names of this protein?
F420-non-reducing hydrogenase vhu iron-sulfur subunit D.
What is the protein family that this protein belongs to?
Belongs to the MvhD/VhuD family.
Protein: CUE_DROER
Sequence: MIRIRFGMDVLLVLLLATCLLSPAHGTPLEWDFAVTLRTKIQFMDSSWQTIATAAHEFDELSAITFDESEELIYFNDMRHQNGSIFSLKRDLVAANHVVEQRIARTGNESVGGLAYDPLTMNLFWSDIEQRKIFFAPIDGSAAPKVLVDLSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGNNRTVIINSTIDMPRGIVVDQLSDRLFWIDDLKGVFFAIESSKLDGSDRLVVLKDKHHEPLNLAVTNDAIYWTDRTTRSVWSHPKVPVIRVTTTSKPVEEDSTDSTDFKDPEPVNEDCPLVRVANLSEEVRGIVVRTGFYQRLQKDHHCASIVRKVKERVDAQNTKFEVRSLQDQKMKILQDERCMNHGEYKPATDLCICPTGFKGSRCEIRECHNYCVHGTCQMSESAYPKCYCQPGFTGERCEVSVCAGLCLNGGHCRASKDEKEAPSCECPAKFGGARCEQNSTEICTLFCRLLKHEPEMYVPFGCHSICEELAQDNSTNIAVPQYQHLEVCLTPKVWTSSVIIILVIGIVSSLLLVAVIVHGIRRLYKPKRPRIRKTFVVRKQARTNSAGDTPLTNRPLATEQCEITIENCCNMNICETPCFDPKLVEQTLSKSSCKEDKKILIHNMEDDLY
What is the function of this protein?
Has a role in spermatogenesis and oogenesis.
What are the official names of this protein?
Protein cueball.
What is the protein family that this protein belongs to?
Belongs to the cueball family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RSSA_DROPE
Sequence: MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNIINLGKTWEKLQLAARAIVAIENASDVFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPMTDHQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRTVEWPVVVDLYFYRDPEEAEKEEAAAKELLPPPKIEEVVDHPVEETTNWADEVAAETVGGVEDWNEDTVKTSWGSDGQF
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Required during oogenesis and imaginal development.
What are the official names of this protein?
40S ribosomal protein SA, Protein stubarista.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May associate with nascent RNP complexes within the nucleus.
Protein: RPIA_CAUVN
Sequence: MSADDQKRISGEAAAELVENGMVVGLGTGSTAAWFVKALAARGLKDIRGVPTSDATAALARELGIPLAALDDVKTVDLTVDGADEIGPGLSLIKGGGAALLREKLVWEASTRCVVIADAAKRVPALGKFPLPIEVVRFGHVHTGYRLADIAAEFDLPPPRLRTAERGMVVTDGGNLIYDMASGKIEDPTALAAALKSVTGVVDHGLFLDLADEALVGTDEGVVRLQP
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PLYB2_POLPI
Sequence: SVDMVMKGIKLWPL
What is the function of this protein?
Venom component which lacks hemolytic or antibiotic properties, but produces an inflammatory response via mast cell degranulation and produces a chemotactic effect on leukocytes.
What are the official names of this protein?
Polybine-2, Polybine-II.
What are the subcellular locations of this protein?
Secreted.
Protein: YXJM_BACSU
Sequence: MNGQTPARHYYKKLVPSLILILNCIQFLSHPTKADPILLAFVFAVYLAFIWIIPYVASTAVSLSIFIGLWLLTDFFWAVSGQEQGAAYFLIVFLMIYAAFRLPSRLSLIFTACLIGGNILLLSSQGGSLNTIISNISIMLGLYVLFSSMRFRREARREAERNHAELAKMHVQLEHAHKELQKAHAELQEASVLSLRYAVLEERTRIARDIHDSIGHELTSVIVQLQSLPYILKSSKEDSEKVIQNVLSVARECLQEVRSVVHQMGRSESMVGLTALRGLIHQVEERSGLHVSLDTAGLSEESWPPNVSETIYRILQEALTNIIRHADASHAAAVISNDKSHLYVTITDDGQFTGSLTYGFGLTGMKERAEKAGGSLTFSAVQPSGLKIELSLPLMTTNKEQKDEQR
What is the function of this protein?
Probable member of the two-component regulatory system YxjM/YxjL.  May activate YxjL by phosphorylation.
What are the official names of this protein?
Sensor histidine kinase YxjM.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTD2L_MOUSE
Sequence: MATRARGFSLLRGRLGRGPVRAPGVAERAWRGFGSSGRRHEAVIISGTNMAKQIQKEIQQGVESWIALGNRRPHLSIILVGDNPASHTYVRNKIKAASAVGICSELIIKPKNVSQEELLDITDQLNMDPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAVWEIIKRAGIETFGKNVVVAGRSKNVGMPIAMLLHTDGEHERPGGDATVTIAHRYTPREQLKAHTQLADIIIVAAGIPRLITADMVREGAAVIDVGINYIQDPVTGKTKLVGDVDFEAVKKKASFITPVPGGVGPMTVAMLLKNTLLAAKNIAY
What is the function of this protein?
Bifunctional mitochondrial folate-interconverting enzyme that has both NAD/NADP-dependent methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities.
What are the official names of this protein?
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial, NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein, MTHFD2-like.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y947_STAAN
Sequence: MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYKRFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK
What are the official names of this protein?
UPF0223 protein SA0947.
What is the protein family that this protein belongs to?
Belongs to the UPF0223 family.
Protein: DAPA_LISW6
Sequence: MDLGKVITAMVTPIHPEKDKVCKKRIHHLVNHLIANGSDGLVVAGTTGESPTLSHDEKIKLFRQVIETNAGRAKLIAGTGSNNTAETIAFTKEVAELGGIDAVLVVAPYYNKPNQDGLYAHFVAVAEASDLPVVIYNIPGRSVVNIEPETIIRLAKLPNIVGVKESSGNLDNISKIIAETPEDFLVYSGDDSLTLPILAVGGDGVISVASHVVGKEMQEMIQAFARGEVQKAASIHRSLLPIMNGLFAVPNPAPTKYLLNQQGISVGPVRLPLVDLNAEQGTKLQAILEGLSK
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAMM_MAGSA
Sequence: MRKSGCTVCSRSIGWVGLAVNTVLMVMKAFVGLIGGSQAMLADAMYSLKDMLNALMVVIGTTISSKPLDAEHPYGHGKVEFILSMVVSVVFIGLTGYLLVHAVQILLDESMHRTPHLIVLWAALVSVGVNVAMYFYSRCVAIETNSPIIKTMAKHHHGDATASGAVALGIIGAHYLNMPWIDPAVALWETIDLLLLGKVVFMDAYRGLMDHTAGEAVQNRIVDTAERVPGVRGVIHLRARYVGQDIWADMIIGVDPEHTVEQAHDICEAVQAAVCGKMRRIESLHVSAEAREAGDTSKPTFSEEPLTYDEVMLSKVDN
What is the function of this protein?
Probably plays a role in biomineralization (Probable).  Required for stable accumulation of MamB (By similarity).  Probably binds and transports iron.  May nucleate iron crystal formation (By similarity).
What are the official names of this protein?
Magnetosome protein MamM, Probable iron transporter MamM.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein. Cell inner membrane; Multi-pass membrane protein.
Protein: PXPA_BACLD
Sequence: MNQVDLNCDLGESFGAYKIGLDEEILEFVTSANIACGFHAGDPGVMRKTVKMAAEKGVKIGAHPGLPDLAGFGRRNMAITPEEAYDLVVYQIGALSGFLKAEGVTMQHVKPHGALYNMAAQSRELSDAIARAVYQTDPELILFGLAGSELVLAGERAGLKTAHEVFADRTYQEDGTLTSRRQNDALIQDDDEAVGQVIRMVKEGKVRSLQGTDVSLKADTVCIHGDGAHALHFAKKIRRELRAADIKVQAFST
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: TSSK4_HUMAN
Sequence: MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT
What is the function of this protein?
Serine/threonine kinase which is involved in male germ cell development and in mature sperm function (By similarity).  May be involved in the Cre/Creb signaling pathway (By similarity).  Phosphorylates CREB1 on 'Ser-133' in vitro and can stimulate Cre/Creb pathway in cells (PubMed:15964553).  Phosphorylates CREM on 'Ser-116' in vitro (By similarity).  Phosphorylates ODF2 on 'Ser-95' (By similarity).
What are the official names of this protein?
Testis-specific serine/threonine-protein kinase 4, TSK-4, TSSK-4, Testis-specific kinase 4, Serine/threonine-protein kinase 22E.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum. Note=In spermatozoa, present in the sperm head and in the flagellum.
Protein: OSTCN_CAMHE
Sequence: YLDHGLGAPAPYVDPLEPKREVDELADQMGFQEAYRRFYGTT
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium (By similarity).
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHYD1_HUMAN
Sequence: MACLSPSQLQKFQQDGFLVLEGFLSAEECVAMQQRIGEIVAEMDVPLHCRTEFSTQEEEQLRAQGSTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFKSITHSFKVQTLARSLGLQMPVVVQSMYIFKQPHFGGEVSPHQDASFLYTEPLGRVLGVWIAVEDATLENGCLWFIPGSHTSGVSRRMVRAPVGSAPGTSFLGSEPARDNSLFVPTPVQRGALVLIHGEVVHKSKQNLSDRSRQAYTFHLMEASGTTWSPENWLQPTAELPFPQLYT
What is the function of this protein?
Isoform 3 probably lacks enzyme activity.
What are the official names of this protein?
Phytanoyl-CoA dioxygenase domain-containing protein 1, Protein PHYHD1.
What is the protein family that this protein belongs to?
Belongs to the PhyH family. PHYHD1 subfamily.
Protein: CARB_COREF
Sequence: MPKRSDINHVLVIGSGPIVIGQAAEFDYSGTQACRVLKEEGLRVTLINSNPATIMTDPEMADHTYVEPIEPEYIEKIFQKEIEQGHPIDTVLATLGGQTALNAAIQLDRLGILEKYNVELIGADIDAIERGEDRQKFKDIVATIGGESARSAVCHNMDEVYATVEELGLPVVVRPSFTMGGLGSGLAYTMEDLDRIAGGGLAASPEANVLIEESILGWKEYELELMRDGDDNVVVICSIENVDALGVHTGDSVTVAPAMTLTDREYQIMRDQGIAIIREVGVDTGGCNIQFAVNPEDGRIITIEMNPRVSRSSALASKATGFPIAKLAAKLAIGYTLDEVTNDITGVTPAAFEPTLDYVVVKAPRFAFEKFPGADDTLTTTMKSVGEVMSLGRNYIAALNKALRSLETKQLGFWTKPDEYFAGERATDLQAVLEDLRRPTEGRLYDVELAMRLGATIEELYDASSIDPWFLAELKALVDFREKLEDAPVLDEALLREAKFMGLSDLQIAAVRPELAGEDGVRRLRHSLGIRPVFKTVDTCAAEFEAKTPYHYSAYELDPAAESEVAPQTEREKVLILGSGPNRIGQGIEFDYSCVHAALELSRVGYETVMVNCNPETVSTDYDTADRLYFEPLTFEDVMEVYHAESESGTVAGVIVQLGGQTPLGLAERLKAAGVPIIGTSPEAINMAEDRGEFGDLLGRAQLPAPAFGTAHSFEQARAVANEIGYPVLVRPSYVLGGRGMEIVYDEASLEDYIQRATELSTEHPVLVDRFLDNAIEIDVDALCDGEEVYLAGVMEHIEEAGVHSGDSACALPPMTLGAQDIEKVRQSTRALALGIGVKGLMNVQYALKDDILYVIEANPRASRTAPFVSKATGVHLAKAASRIAVGATIADLRAEGMIPTGYDGGSLPLDAPIAVKEAVLPFNRFRRPDGRSLDTLLSPEMKSTGEVMGLADNFGAAYAKAETGAFGTLPTEGTVFVSVANRDKRSVILAIQRLDSMGFNILATEGTAGMLRRNGIDCEVVLKSSDVREGVEGRSIVDRIRDGEVDLILNTPAGSAGARHDGYEIRGSAVTVGVPLVTTVQGVTAAVQGIEALRRGELTVRALQELDHAVKA
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: TRPB_STRP2
Sequence: MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECIIYMGEEDVKRQALNVFRMELLGAKVEAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSTLGPHPFPEIVRDFQSVIGREAKQQYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAKKGEAHA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: NUOK_PSEMY
Sequence: MTGIPMEHGLALAAALFCIGLVGLMVRRNILFILMSLEVMMNAAALAFVVAGARWGQPDGQVMFIMVITLAAAEASIGLAILLQLYRRFNTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_STAAS
Sequence: MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: DDL_LACCB
Sequence: MKIVVLAGGRSTERNVSISSGYRITNALRQKGQQATFIDLFLGYDLEGKTVEQVFDDANTSKDLNISDAILTDEDINKLRPDGSTQLFGPNVMAICKAADIVFLALHGGDGENGKVQAVFDINGVKYTGSGPLASGITMNKVFSKEVMLYHGIQTSGFKEFKRDQGPKQTVPFDFPVVVKPTSGGSSVGTHIIHNQEELESGLEDVFRFDNSAIVEEFTPGREFSLGVVNGHAYSAIEIKVRSGWYDFKHKFQAGYTDFITPPKDLDEDVHQAMKDVAVQTMDVLGLQNYGRIDFFANEKGVWVIEANNLPGMTPLSLLPQEAEADGVDYGDLVMDIVNGKLKLYADGMTEAGLLTK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MISFA_HUMAN
Sequence: MIVLGWMFFVGLVCYMGTFPELMPPTLKWQERWPVQESKTQLRRRALGEDLLQNHVEGI
What is the function of this protein?
Regulates sperm development.  May be involved in mitochondrial sheath formation.
What are the official names of this protein?
Mitochondrial sheath formation-associated protein, Putative transmembrane protein SPTY2D1OS, SPTY2D1 antisense RNA 1, SPTY2D1 opposite strand.