PharMolix/UniProtQA huggingface dataset:
Protein: TMED3_RAT
Sequence: MGNEVPRASSFQMLMLLLLLLLLRAERLRGAELTFELPDNAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPMGNIIYRETKKQYDSFTYKTEVKGVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVIDSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLKSFFTEKRPINRAVHS
What is the function of this protein?
Potential role in vesicular protein trafficking, mainly in the early secretory pathway.  Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network (By similarity).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 3, p24 family protein gamma-4, p24gamma4.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Note=Probably cycles between compartments of the early secretatory pathway.
Protein: PSBJ_CHLVU
Sequence: MSNTGTTGRIPLWLVGTVAGTAALTLVAVFFYGSYVGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: EFTS_CAEEL
Sequence: MFARAPFVRLLSTTSRNLAEAEKKVSKEALMALRKKTGYSYVNCRKALIQFGENDMDSAVKWLKEAAAKEGWAKAAKLGTRVTSNGLVSVVTDNSTAAVVELSCETDFVARSGAFKDLLSNISNSVLAKAKPQSISSGSKLQEFTYDLGDLTDSDGKNMREVLSLSIGKLGENMTVRRVKAFKAPEGTTLFGASHPKDGTDDIPMGRFISLIALNQSSPGSISSQQLAGQICQHIIGMSPESLGEAAESVKTQEGLRSQEGHDPNADPVVVTNIDESETALLRQAFMLNPSQSVHEYLKSHNANILDFVRVELGSE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, mitochondrial, EF-Ts, EF-TsMt.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TMD11_MOUSE
Sequence: MQIQTILLCFSFSFSAAFYFHAGEREEKCIIEDIPSDTLITGTFKVQQWDIVRHDFLESAPGLGMFVTVTTYNDEVLLSKLYGAQGTFYFTSHSSGEHIICLESNSTQFVSFGGSKLRIHLDIRVGEHDLDAAIVQAKDKVNEVTFKLQHLIEQVEQILKEQDYQRDREENFRITSEDTNRNVLWWAFAQILIFISVGIFQMKHLKDFFIAKKLV
What is the function of this protein?
Part of a complex whose function is to bind Ca(2+) to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 11, Glycoprotein 25L, GP25L, p24 family protein alpha-1, p24alpha1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: FOLM_SHIBS
Sequence: MGKAQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAIDGLIKAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKLGAPLADVLACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALDNMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVDYLLTSCFVTGRSFPLDGGRHLR
What is the function of this protein?
Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin.  Also has lower activity with dihydrofolate.
What are the official names of this protein?
Dihydromonapterin reductase, H(2)-MPt reductase, Dihydrofolate reductase, DHFR.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FolM subfamily.
Protein: HIGB_PROVU
Sequence: MIKSFKHKGLKLLFEKGVTSGVPAQDVDRINDRLQAIDTATEIGELNRQIYKLHPLKGDREGYWSITVRANWRITFQFINGDAYILNYEDYH
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system (PubMed:19423702, PubMed:24257752, PubMed:8645296).  A ribosome-associated translation-dependent mRNA interferase.  Inhibits translation by sequence-specific cleavage of mRNA.  Prefers either in-frame or out-of-frame 5'-AAA-3' codons (lysine).  Cleaves also the first three AAAs of stretches of four or more A sequences.  20% of codons containing AA are cleaved and occassionally cuts even at a single A (PubMed:19423702).
What are the official names of this protein?
Endoribonuclease HigB, Host inhibition of growth protein B, Killer protein, Toxin HigB, mRNA interferase HigB.
Protein: CYSH_SYNE7
Sequence: MPALLPSLTEINAQLADQAATQIIQWAATEFGSGLVLSTSFGIQSAVMLHLATQVQPDIPVIWIDTGYLPTETYRFAAELTERLKLNLKVYQSEISPARMEALYGRLWESESVEDFNRYDQMRKVEPMNRALQELGATAWLSGVRRQQTAHRQSMEIVELKRDRYAIRPILGWHSRDVYQYLTAHDLPYHPLFDQGYVTVGDWHSSRPLQADDSDERSTRFRGLKQECGLHL
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y188_CLOPE
Sequence: MGLFAVIDIGGTSIKYGVINEDGTLLETNDRDTEAYKGGLSIIEKVKDIIHELKINNDISGICVSTAGMVCPKEGKIVYAGPTIPNYTGVEVKKILEEEFNLPCFVENDVNCAALGEFFGGAGKGTHSMACLTIGTGIGGALIIDGKVLHGFSNSAGEIGYMMVNGEHIQDIASASALVKNVALRKGVEPSSIDGRYVLDNYENGDLICKEEVEKLADNLALGISNIVYLINPEVVVLGGGIMAREEVFRPLIENSLRKYLIESVYNNTKIAFAKLKNTAGMKGAYYNFKENFNK
What are the official names of this protein?
Uncharacterized protein CPE0188.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: SDS23_YARLI
Sequence: MDKENASVEKAPTTPSLAVPAPSQASPQSPQAALSPSNSSIQATFARARKGSHASQMERPNNRDFAIPASPTVGESSIAELVTAPPAVTPSRSRSSSAASNNQAAMSPVFPAYDDSNAKHYRRWEDDRLDLMVQPDKLVFVEGDTPVEKAFDKLVENHFTSLPVRTAPEHKSVSHSFDYADLNAYLLLVMGYVDAADTTPEALENVKKARSGQPVPVNFVAGLGAKDPFICVPRDSTLATAVEILGSGVHRFAVTEGPASDAVIGILSQRRTVRYIWENGRLFKTLEPLFQTPLTDLGLAQPNPNVLTIGGDEYVIAALRKMNAQNVSSLAVVDASNNLLGNISVVDVRLVSKSSQSHLLKATCAHFLSVILNARGLEDGKDSFPVFHVTPQTSYGRTIAKMVATNAHRLWVVQPDVPSPQPSTPSGQPASKTHGPSHHAAHNGKLIGVVSLTDILNVLGRHAGNSDLDPHFARRNRRRSSSSSVRSRSSYEQFRRSISIDRGQR
What is the function of this protein?
Involved in DNA replication and cell separation.
What are the official names of this protein?
Protein SDS23.
What is the protein family that this protein belongs to?
Belongs to the SDS23 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RECR_THIDA
Sequence: MQPAALESLINALRVLPGVGPKSAARMAYHLLQRDRRGAETLAGALGHALTHLHHCRLCNNFSEAEVCEVCASTRRDRRQLAVVEMPADFNMMEATQSYNGLYFVLMGRLSPLDGIGPREIHLDRLINRALDGTVEEVILATNFTPEGEATAHTIGELLKARGLKVSRLARGVPVGGELEYVDSGTLAQAVRDRRAL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: HSLO_SHEB8
Sequence: MNQDTLHRYLFDNADVRGELVQLQDSYQQVISAQEYPAVLQVLLGELMAATSLLTATLKFSGDISVQLQGNGPVSLAVINGNNLQELRGVARWNAELADDASLTDLFGQGYMVITLTPDEGERYQGVVALDKPTLAACVEEYFNQSEQLPTGIWLFADGKQAAGMFLQILPSKEDHNPDFEHLSQLTSTIKAEELFTLDAESVLHRLYHQEEVRLFDPIDVSFKCTCSHERSAGAIKTLDQAEIEAILAEDGKIEMGCEYCHAKYIFDAIDVAALFANGQTSTTQQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CA14_CONAA
Sequence: MGMRMMFTVFLLVVLATTVVSFMSGRASHGRNAAASDLIALTIKGCCSVPPCIANHPELCV
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxine-like Am1.4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y436_PYRFU
Sequence: MKRGLFLTLFFLLILGIAGHWAWNSFGSKPNSMQVTNNIELIEIDHDVLIGLGNGFFVKVDNSTFMMSLKVLVKGEQVEHRVYRLKNGKSELVGKLDVPFVVDVPALWIDNEVLLFGGMNPGNITLVPVVYAYNPENGSMREFAEMPFRDYDQLSLLWDGSKAYLFVRFLNGNLSAYSFDPYAKKFQCLDLGFPEGFVFPGTSKYAAVWYKGKGYFVHGDRIAVFDPSSKNLVWAQVRLPDKYWARTAVATDRGIYIFGGFDDNVNFSRNIYLFVPENNTLTRVGTLPYPLGQAPGGWDGRRIYIVGGRGPGPNKYIVIFTPKG
What are the official names of this protein?
Kelch domain-containing protein PF0436.
Protein: LIPA_STAAT
Sequence: MATKNEEILRKPDWLKIKLNTNENYTGLKKMMREKNLNTVCEEAKCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNLKHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASRPDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEIYETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGPLVRSSYHADEQVNEAAKEKQRQGEAQLNS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPFR2_XENRU
Sequence: GFGSLLGKALKAGLKLGANLLGGAPQQ
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Caerulein precursor fragment R2, CPF-R2.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC_ECO24
Sequence: MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ACLT_ASPOR
Sequence: MCDSSQSTADVLIIGGGPAGSNAAWELGQAHHRVILFNASIDRLRDPDVNTASTRPALDLLLHSRRKTPDVFRPFRQEIGKESSEVSVHNQRITQVQRLPNGFFQAEDDVGHVWTAKVLVLADGAEEILPDIDGYDTCWEQQRILTHPAEDEPRSLISSCLAVLAVGDLAELTMALHTVWQARQFAASVRVYTHGDEDLARALETRISPDARIAIQTTPIQSLQPGSDSPSQVVVHLADGSSIVESHVYHRPASQLQGPFARQLNLELTESGAIRISARVPYMTSLDGVYAGGDCASLGQRTLFKALAMGQGLAAAVAARLERGNWGNAVEEQD
What is the function of this protein?
Thioredoxin reductase; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).  The non-ribosomal peptide synthetase (NRPS) aclP is responsible the formation of the diketopiperazine (DKP) core from the condensation of 2 phenylalanine residues (PubMed:25302411).  One Phe residue is tailored into chlorotyrosine by hydroxylation and chlorination, whereas the second Phe undergoes an unprecedented C-C bond cleavage to be converted into glycine (PubMed:25302411).  After formation of the DKP, sulfur is incorporated into the DKP by conjugation with glutathione by aclG, followed by its stepwise degradation to the thiol by aclI, aclJ and aclK, and the dithiol oxidation by aclT (PubMed:25302411).  In addition, oxygenases (aclB, aclC, aclL and aclO) and O-methyltransferases (aclM and aclU) act as tailoring enzymes to produce the intermediate dechloroaspirochlorine (PubMed:25302411).  Ultimately, chlorination of dechloroaspirochlorine by the halogenase aclH is the last step in the aspirochlorine pathway (PubMed:25302411).
What are the official names of this protein?
Thioredoxin reductase aclT, Aspirochlorine biosynthesis protein T.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
Protein: HISZ_PARP8
Sequence: MSTWLLPENIADVLPSEARKIEELRRRLLDRFRAYGYEMVMPPLLEYLESLLTGGGRDLNLRTFKLVDQLSGRTLGLRADITPQVARIDAHLLNRQGVTRLCYAGNVLHTRPRGLHATREQIQIGAEIYGHAGLEADLEIQQLMLDALHLAGLGRVRLDLCHAAVLGALVDSEPAAAELGESLYETLAGKDVPLLTELTANLPPVTRDALRALPTLYGDATVLEEARARLPNAPEISRALDDLAFLAQQVGGAEVMIDLADLRGYAYHSGVMFSAYVDGVPNAVARGGRYDKVGQAYGRARAATGFSLDLREVARISPIEARSSAILAPWQAGEALRTSVAALRDAGEVVIQALPGHDHALDEFACDRVLVERDGQWVVELKS
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACHB4_HUMAN
Sequence: MRRAPSLVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAFPPSKSCVTKPEATATSTSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFWLRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLPPLFQTHAASEGPYAAQRD
What is the function of this protein?
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
What are the official names of this protein?
Neuronal acetylcholine receptor subunit beta-4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Beta-4/CHRNB4 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: STDH4_CAEEL
Sequence: MKVVTGATDGIGRSYALDLARRGFNIFLISRTKSKLVKTKKQILNKYSDIEVRYAICDFTRVSYEDYKRLLHSLNEVDIGILINNVGMCFDNPEVLHRVEGGIDTLTNVINVNILPVTLLTAGILPQMMARKSGIIVNIGSAAGSIHMAKWSVYSATKKYIEWFTSILQKEYENEGIICQTITPLLVSTNMIKNPLSSIFCPNSDSFAKSSLNTIGNSSSTTGYITHQIQFELIKFVPEIIIDLFVKNLNNQLLDYQLDKKRV
What are the official names of this protein?
Putative steroid dehydrogenase 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
Protein: DNAA_RHOOB
Sequence: MNDDPNALARIWIDVVADLTSDSPGGDLPPLTRGQKAWLALVKPLTLAQGFALLSVPSPFAQEAIERDLREPILHALGRHLGEQVEGLGVRIAAPVDDEPESEAPSRERRPDPEPVHTPRHLEPSVTSSGTFRRRRFGSGDDQPYSDTTDFEEVDDDSEALASVHESWPSYFTKPPAGPAPAATGGNSLNAKYTFDTFVIGSSNRFAHAAAVAIAEAPARAYNPLFIWGASGLGKTHLLHAAGHYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRRYRETDVLLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVVSSDRPPKQLATLEERLRTRFEWGLITDVQPPELETRIAILSKKARMDRLEVPDDVLELIASRIERNIRELEGALIRVTAFASLNRQPLDLTLAEVVLRDLMPDSSSLEINAATIMAVTAEYFNMSIDDLCGPGKARPLASARQISMYLCRELTDLSLPKIGQTFGRDHTTVMYADKKIRKEMTERRKVYDQVQELTARIKQRSKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_ECODH
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SSPP_GEOTN
Sequence: MTNKNDSKDMRKNVSKGDNPGQPEPLDGSKKVKNRNHTRQKHNTSHDM
What are the official names of this protein?
Small, acid-soluble spore protein P, SASP P.
What is the protein family that this protein belongs to?
Belongs to the SspP family.
What are the subcellular locations of this protein?
Spore core.
Protein: KATG1_MYCS2
Sequence: MPEDRPIEDSPPIGEAQTDAPAGGCPAGFGRIKPPVAGGSNRDWWPNQLNLKILQKNPDVINPLDEDFDYRSAVQNLDVDALRADIVEVMHTSQDWWPADFGHYGPLFIRMAWHAAGTYRVSDGRGGAGAGMQRFAPLNSWPDNASLDKARRLLWPVKKKYGKNLSWADLIVYAGNVALEDMGFRTAGFAFGREDRWEPEEDVYWGPEQEWLDDKRYTGERDLENPLAAVQMGLIYVNPEGPNGNPDPQASAIDIRETFGRMAMNDVETAALIVGGHTFGKTHGNGDASLVGPEPEAAPLEEVGLGWRNPQGTGVGKDAITSGLEVTWTHTPTKWDNSFLEILYGNEWELTKSPAGANQWKPKDNGWANSVPLAHEDGKTHPSMLTSDLALRVDPIYEQITRRWLDHPEELAEEFAKAWFKLLHRDMGPVTRYLGPEVPKDTWLWQDNIPAGNDLSDDEVAKLKELIADSGLTVSQLVSTAWKAASTFRSSDLRGGANGGRIRLQPQLGWEANEPDELAQVVRKYEEIQKASGINVSFADLVVLGGNVGVEKAAKAAGFDVTVPFTPGRGDATQEETDVDSFAYLEPKADGFRNYLGKGSDLPAEFKLIDRANLLGLSAPEMTTLVGGLRVLDVNHGGTKHGVLTDKPGALTTDFFVNLLDMSTAWKPSPADDGTYIGTDRATGSPKWTGTRVDLVFASNSQLRALAEVYAEDDSKEKFVKDFVAAWTKVMDADRFDVA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.  May play a role in the intracellular survival of mycobacteria.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: SYT_ACET2
Sequence: MIKITLKDGSVREYNEGITIKEVAESISAGLARVALAGEVNGEVKDLSYPLENDCTLNLLTFDDEGGRDAYRHTTSHILAQAVKRLYPDAKLAIGPAIENGFYYDFDVEKPFSVEDLEKIEEEMKKIIKEDYKLERFTLPREEAIKFMEERNEPYKVELIRDLPEGETISFYKQGDFVDLCAGPHIESTGKVKAFKLMSVAGAYWRGNEKNKMLQRIYGTSFTKKSDLDAYITRIEEAKKRDHRKLGRELDLFDIYEEGPGFPFFMPKGMVLRNVLEEYWREEHRKAGYQEIKTPIILNEELWHRSGHWDHYKENMYFTKIDEADFAIKPMNCPGGMLVYKRKLHSYRDLPQRLAELGLVHRHELSGVLHGLMRVRCFTQDDAHIFMTPDQIESEILGVISLIDDFYKVFGFKYHVELSTRPENSMGSDEDWERATNALKNALEKKGIDYKINEGDGAFYGPKIDFHLEDSIGRTWQCGTIQLDFQMPERFDLTYIGPDGEKHRPVMIHRVVFGSIERFIAILTEHYAGAFPVWLSPVQVKILPILEKQHDYVAEVKKALEEKGVRVEADLRNEKIGYKIREAQLEKVPYMLVIGDKEMENRTVAVRSRKDGDLGPMRLEDFVNRIVEAIKNKEN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPD_STAAU
Sequence: MTSISAKLRFLILIIIDSFIVTFSVFLGYAILEPYFKGYSIDLLVLSSVILLVSHHIFAYVFNLYHRAWEYASVSELMSVLKAVTSSIVVTLLLVSLLISESPFLRLYFITWMMHLLLIGGSRLFWRVYRRYFIDNAVEKKATLVVGAGQGGSVLIREMLRSQDMRMQPVLAVDDDKNKQKMTITERVKVQGYVEDIPELVKKFRIKKIIIAIPTLSQKRLNEINKICNIEGVELFKMPNIEDVLSGELEVNNLKKVEVEDLLGRDPVELDMALISRELTNKTILVTGAGGSIGSEICRQVSKFDPQKIILLGHGENSIYSIHQELSKTYGNRIEFVPVIADVQNKTRILEVMNEFKPYAVYHAAAHKHVPLMEYNPHEAIRNNILGTKNVAESAKEGEVSKFVMISTDKAVNPSNVMGATKRIAEMVIQSLNEDNSKTSFVAVRFGNVLGSRGSVIPLFKNQIESGGPVTVTHPEMTRYFMTIPEASRLVLQAGALAQGGEVFVLDMGKPVKIVDLAKNLIRLSGKKEEDIGIEFSGIRPGEKLYEELLNKNEIHPQQVYEKIYRGKVDHYIKTEVDLIVEDLINNFSKEKLLKIANR
What is the function of this protein?
Required for the biosynthesis of type 1 capsular polysaccharide.
What are the official names of this protein?
Capsular polysaccharide biosynthesis protein CapD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PTQB_ECOL6
Sequence: MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLAGEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKKAAAN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ChbABC PTS system is involved in the transport of the chitin disaccharide N,N'-diacetylchitobiose (GlcNAc2).
What are the official names of this protein?
PTS system N,N'-diacetylchitobiose-specific EIIB component, EIIB-Chb, IVcel, N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_SACS2
Sequence: MVEKHLLEFLEKLQFLISKNVKISHYGIENVKKICGVDIAYKGNLGFSVGVSMDINSGDYNYKSYVGEVNFPYIPGFLFMREAPLMIKAIEGLDCHLLLVDGHGIAHPRKSGIAAVIGVLLDFPTIGVAKSRLTGDLVNESEITYVYLNGEKVGVKFGRYFYSPGNKVDLQDCIELGKRGYPKVLKIADMLTKKIKKE
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.