PharMolix/UniProtQA huggingface dataset:
Protein: TACB1_TACTR
Sequence: YVSCLFRGARCRVYSGRSCCFGYYCRRDFPGSIFGTCSRRNF
What is the function of this protein?
Exhibits stronger antimicrobial activity against the Gram-positive bacteria (S. aureus (IC(50) is 7. 4 ug/ml)) and fungi (C. albicans (IC(50) is 3. 0 ug/ml) and P. pastoris (IC(50) is 0. 1 ug/ml)) than Gram-negative bacteria (E. coli no inhibition at 100 ug/ml).  Binds to chitin (4. 3 uM are required to obtain 50% of binding).  Does not cause hemolysis on sheep erythrocytes.  Has no blocking activity on the P-type calcium channel.
What are the official names of this protein?
Tachystatin-B1.
What are the subcellular locations of this protein?
Secreted.
Protein: UBE3A_HUMAN
Sequence: MEKLHQCYWKSGEPQSDDIEASRMKRAAAKHLIERYYHQLTEGCGNEACTNEFCASCPTFLRMDNNAAAIKALELYKINAKLCDPHPSKKGASSAYLENSKGAPNNSCSEIKMNKKGARIDFKDVTYLTEEKVYEILELCREREDYSPLIRVIGRVFSSAEALVQSFRKVKQHTKEELKSLQAKDEDKDEDEKEKAACSAAAMEEDSEASSSRIGDSSQGDNNLQKLGPDDVSVDIDAIRRVYTRLLSNEKIETAFLNALVYLSPNVECDLTYHNVYSRDPNYLNLFIIVMENRNLHSPEYLEMALPLFCKAMSKLPLAAQGKLIRLWSKYNADQIRRMMETFQQLITYKVISNEFNSRNLVNDDDAIVAASKCLKMVYYANVVGGEVDTNHNEEDDEEPIPESSELTLQELLGEERRNKKGPRVDPLETELGVKTLDCRKPLIPFEEFINEPLNEVLEMDKDYTFFKVETENKFSFMTCPFILNAVTKNLGLYYDNRIRMYSERRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFTYDESTKLFWFNPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYRKLMGKKGTFRDLGDSHPVLYQSLKDLLEYEGNVEDDMMITFQISQTDLFGNPMMYDLKENGDKIPITNENRKEFVNLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNLDFQALEETTEYDGGYTRDSVLIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLKMIIAKNGPDTERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITYAKGFGML
What is the function of this protein?
(Microbial infection) Catalyzes the high-risk human papilloma virus E6-mediated ubiquitination of p53/TP53, contributing to the neoplastic progression of cells infected by these viruses.
What are the official names of this protein?
Ubiquitin-protein ligase E3A, E6AP ubiquitin-protein ligase, HECT-type ubiquitin transferase E3A, Human papillomavirus E6-associated protein, Oncogenic protein-associated protein E6-AP, Renal carcinoma antigen NY-REN-54.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GUAA_USTMA
Sequence: MTEAIHSQYDSILILDFGSQYSHLITRRCRELNVYCEMLPCTQKIKDLDWKPKGIILSGSPYSVYDEVAPRVDPDVFTAGVPVLGICYGLQEIAWNHGGKVDPHDKREYGHAMVEVVKHGVPHLDALFKNWEGSVQVWMSHGDQLSKAPEDFVVIAKTPTAPFAAMAHKSKPIYGVQFHPEVTHSLRGVELFDSFVDICACRRDWTMETFIDKEIKRIREIVGPKGQVLGAISGGVDSSVAAKLMHEAIGDRFHAVMVDNGVLRTNEAAQVYEMLSKDLGVNLTVVDASEQFLSRLKDVEDPEQKRKIIGNTFIHVFEAEVAKLEKQAEDEEAAALAAGKPQEAKGKFEYLLQGTLYPDVIESISFKGPSATIKTHHNVGGLLEDMKLKLIEPLRELFKDEVRALGKLLGIPAHLVGRHPFPGPGLAIRILGPVTREQVKILQHADSIYIDEIRAAGLYDQISQAFAVLLPVRAVGVQGDKRTYDQVIALRAAATTDFMTATWYPFPAEFLSKVSNRITNEVQGVNRVVLDISSKPPATIEWL
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_STRP3
Sequence: MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSVQVRSLACPKFVPIVESNEMCSSIAKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVKHRFFTTANPEIFQEIASIWLKQKINVEHVTL
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: CSPLL_ORYSJ
Sequence: MRQQQAGGVGDGVSPGNVPVCYYGPGGRVPSSLERRARAAEVLLRCAACGLAVLAAALLGADRQTRVFFSIQKVARYTDMQSLVLLVIANGMAACYSLIQCARCLVMAYIVISAVAAAMEAALIGKYGQPEFQWMKTCHLYKRFCAQAGGGVACAIAASVNMVGVALISAFNLFRLYGNSNGGGKATTTTMAGGK
What are the official names of this protein?
CASP-like protein Os03g0196400.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHOR_KLEPN
Sequence: MLERLSWKRLALELFLACIPALILGAFVGHLPWFLLAAVTGLLIWHFWNLMRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQMRNKKRRRELGSLIKRFRSGAESLPDAVVLTTEEGAIFWCNGLAQQILNLRWPDDSGQNILNLLRYPEFANYLKQRDFSKPLNLVLNNARHLEIRVMPYTDKQWLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMQEQVLEGATREKALHTMREQTQRMEGLVKQLLTLSRIEAAPALAMNDRIDVPMMLRVVEREAQTLSQEKQTLIFTVDEQLKVLGNEEQLRSAISNLVYNAVNHTPPGTEIRVSWQRTPQGALFSVEDNGPGIAPEHIPLLTERFYRGDKARSRQTGGSGLGLAIVKHAVNHHDSRLEIDSTVGKGTRFSFLLPERLIARNDA
What is the function of this protein?
Member of the two-component regulatory system PhoR/PhoB involved in the phosphate regulon genes expression.  PhoR may function as a membrane-associated protein kinase that phosphorylates PhoB in response to environmental signals.
What are the official names of this protein?
Phosphate regulon sensor protein PhoR.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_VIBVU
Sequence: MDLITLGKAAKDAAFQLATASTAQKNKALAIIADELEANAADILAANSKDIELGRQAGLSEAMLDRLLLNESRLNGIANDVRNVISLTDPVGSEIDSKVLENGMQLSRRRVPLGVVGVIYEARPNVTIDIAALCLKTGNASILRGGKETFFSNMELVKVIQSALAKAGLPAASVQYIEKPDRELVTQLLKLDDYVDMIIPRGGAGLHKMCKENSTIPVIIGGFGISHIFVDETADLAKSVDVVENAKAQRPSACNALDTLLVHERIAEQFLPMLVAKLNGKVTFVVEPKAKAYMTKAEQVRDASDGDFDTEWLSYTLGVKVVADVQEAIDHMREHNASHSDAIMTNHLQNAELFINSAGSAAVYVNASTRFTDGAQFGLGAEVAVSTQKLHARGPMGLEELTSYKWVGKANYLSRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMR1B_PYRFU
Sequence: MYEAIFDLEAITPLFMRGADARSPEFSSASVKGVMRWWFRALAGGYFGNNIEALKEVEEKIFGSTRNKSRVFVRAEVEDVKKGNIYRQASSWADKTIIVWSEYVDYFFFSVLDKRRNRKTKKIDIKTRFEYFDVGSKFSISLSSTDERYFRLAEASLWMTINLGGFGFRARRGAGSLKVQMLREMLL
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA), formerly called psiRNA (prokaryotic silencing) in this organism.  Part of the Cmr ribonucleoprotein complex which has divalent cation-dependent endoribonuclease activity specific for ssRNA complementary to the crRNA (target RNA), generating 5' hydroxy- and 3' phosphate or 2'-3' cyclic phosphate termini (PubMed:19945378).  Cmr4 is probably the subunit that cleaves target RNA.  Cmr complex does not cleave ssDNA complementary to the crRNA.  Cleavage of invading RNA is guided by the crRNA; substrate cleavage occurs a fixed distance (14 nt) from the 3' end of the crRNA.  In vitro reconstitution shows Cmr1-2 and Cmr5 are not absolutely necessary for target cleavage.
What are the official names of this protein?
CRISPR system Cmr subunit Cmr1-2, CRISPR type III-B/RAMP module RAMP protein Cmr1-2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR system Cmr1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_ECOLC
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RBL_HEUMI
Sequence: VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTNLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMLKRAVFARELGVPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREACKWSPELAAACEVWKEIKFEF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ASTB_PARP8
Sequence: MQATEANFDGLVGPTHNYAGLSFGNVASQNNDKSIANPKMAAKQGLRKMKQLADLGFKQGVLPPQERPSMRLLRELGFAGDEAGVIERVAKNAPELLAAASSASAMWTANAATVSPSADTHDGRVHFTPANLTSKLHRAIEHESTRRTLRAMFADPSRFVVHEALPGTPALGDEGAANHTRFCAEYGAKGVEFFVYGRSEYRRGPEPKRFPARQTFEASRAVAHRHGLADDATVYAQQTPDVIDAGVFHNDVIAVGNARTLFCHQLAFVDQKSVYDELRVKLAKLNGEFNVIEVPDAQVSVADAVSSYLFNSQLLLRGDGRQVLVVPQECRENSRVAAYLDELAASKAPIDDVLVFDLRESMKNGGGPACLRLRVVLNEAERAAVAPGVWIDDTLFTRLDDWIEKHYRDRLAPADLADPKLLNESRTALDELTQILGLGSLYDFQR
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: VVHB_VIBVU
Sequence: MLNNKNRNVGRLTVLCCLFAANTFADVQILGSESELSQTIADQYQQNVTLFNGQLNSNDVLYVNVGTATDDEITQAKSHIISGSTVVIDLTQIAGDDARLDWSQKLTGLGLSAPVVVTGVYQGDALVNAIVSDVTDENDNPINDPQAELESVKLSLTHALDRFQSEGK
What are the official names of this protein?
Cytolysin secretion protein.
Protein: MOBA_HAEI8
Sequence: MTITISAVILAGGKARRMGGQDKGLQILGKQSLIEHVINRLQPQIHQISINTNRNQTEYAKFGFPVFSDELPDFQGPLSGMLTALEKTKSDFILFTPCDTPFFPMNLLDKLKSAVKNDRTLIAYACDEEREHPVFCLMSVQLKEKLRHYLASGERRLLQFMKENGGISVKFTQEEGNFENFNTLDDLKKTVI
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FUCI_KLEP3
Sequence: MKKISLPKIGIRPVIDGRRMGVRESLEAQTMNMAKATAALISEKLRHACGARVECVIADTCIAGMAESAACEEKFSSQNVGVTITVTPCWCYGSETIDMDPLRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDETELEMALAWADKHFRYGEDQNAEQYKRNETQSRAVLKESLLMAMCIRDMMQGNPKLAEKGLVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEALLNSSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPDAVERVTGQPLTGRAEHGIIHLINSGSAALDGSCQQRDAQGNPTMKPHWEIEQNEADACLAATEWCPAIHEYFRGGGFSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVALPKAMHDQLDARTNSTWPTTWFAPRLTGKGPFSDVYSVMANWGANHGVLTIGHVGADFITLAAMLRIPVCMHNVEAAKIYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS17_KOSOT
Sequence: MPRKKLVGTVVSNKMDKTVVVRVERTFAHPLYKKTVKRAKKYHAHDEDNSCGIGDIVEIEECRPLSKTKKFKVVRIVKKSVFGEEKLETPENVEMLGGEEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: HMX3_DANRE
Sequence: MPETTQDTCASAKDSPFFIKNLLNSDSKPSKPKPILAPTKAGLDGSFSLSQVGEINFPRFELPTQRFALPAYLERASAWWYPYTLSASAHLHRTEAAQKARDSSPTTGTDRDSPELVLKSDPDAKDDEDDNKSGDEIVLEEGDTEDGKKEGGIDDWKKSDDGADKKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSASESTNTAGNVPVSQPLLTFPHPVYYSHPIVTSVPLLRPV
What is the function of this protein?
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development.  Binds to the 5'-CAAGTG-3' core sequence (By similarity).
What are the official names of this protein?
Homeobox protein HMX3, Homeobox protein H6 family member 3, Homeobox protein Nkx-5.1.
What is the protein family that this protein belongs to?
Belongs to the HMX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BIOB_TRIEI
Sequence: MIAVLKTPLSNHIKANTKALFSSLPKTKNELEISLDDLAKQIISGYRLSREEAIILTQIAGEEDILLLCEAADRVRQACCGNVVDLCSIINVKSGGCSENCSFCSQSVHHPGEDSPIYGLKSTEEILDQAKAAEAAGAKRFCLVSQGRGVKYNSPKSTEFEQILGTVRQILAETNIKPCCALGELTPEQAQALAEAGVTRYNHNLEASEHFYPEIVSTHSWNDRVETVKNLKAAGIQACTGGIIGMGETWADRIDLALALRELEVESVPLNLLNSREGTPLGGLLKLDPYDALKAIAIFRLILPKQIIRYAGGREAVMGDLQALGLKAGINAMLIGHYLTTLGQPPEKDQAMLKSLGLQGGETPIATNGL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: PVK1_HEMMO
Sequence: EAAGLLPFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA-Periviscerokinin-1, CAPA-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y6489_STRCO
Sequence: MRELVRPARLAPGARVAVVAPSGPVPEERLQAGLDVLRGWDLDPVVAPHVLDRHDTFDYLAGTDADRAADLQAAWCDPAVDAVLCARGGYGVQRMADLLDWEAMRAAGPKVFVGFSDITALHEAFATRLGLVTLHGPMAAGIDFIKNARAQEHLRATLFAPETVRVITSGGTPLVPGRARGVTLGGCLALLAADLGTPHARPGARGGLLCLEDVGEETYRIDRYLTQLLRSGWLDGVGGVLLGSWAQCEPYERLRPLLADRLGGLGVPVVEDFGFGHCEGALTVPFGVPAELDADTGTLTLDRPALCSPG
What are the official names of this protein?
Putative carboxypeptidase SCO6489.
What is the protein family that this protein belongs to?
Belongs to the peptidase S66 family.
Protein: HYKK_HUMAN
Sequence: MSSGNYQQSEALSKPTFSEEQASALVESVFGLKVSKVRPLPSYDDQNFHVYVSKTKDGPTEYVLKISNTKASKNPDLIEVQNHIIMFLKAAGFPTASVCHTKGDNTASLVSVDSGSEIKSYLVRLLTYLPGRPIAELPVSPQLLYEIGKLAAKLDKTLQRFHHPKLSSLHRENFIWNLKNVPLLEKYLYALGQNRNREIVEHVIHLFKEEVMTKLSHFRECINHGDLNDHNILIESSKSASGNAEYQVSGILDFGDMSYGYYVFEVAITIMYMMIESKSPIQVGGHVLAGFESITPLTAVEKGALFLLVCSRFCQSLVMAAYSCQLYPENKDYLMVTAKTGWKHLQQMFDMGQKAVEEIWFETAKSYESGISM
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of 5-hydroxy-L-lysine.
What are the official names of this protein?
Hydroxylysine kinase, 5-hydroxy-L-lysine kinase, Aminoglycoside phosphotransferase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BAP31_HUMAN
Sequence: MSLQWTAVATFLYAEVFVVLLLCIPFISPKRWQKIFKSRLVELLVSYGNTFFVVLIVILVLLVIDAVREIRKYDDVTEKVNLQNNPGAMEHFHMKLFRAQRNLYIAGFSLLLSFLLRRLVTLISQQATLLASNEAFKKQAESASEAAKKYMEENDQLKKGAAVDGGKLDVGNAEVKLEEENRSLKADLQKLKDELASTKQKLEKAENQVLAMRKQSEGLTKEYDRLLEEHAKLQAAVDGPMDKKEE
What is the function of this protein?
Functions as a chaperone protein (PubMed:9396746, PubMed:18287538).  Is one of the most abundant endoplasmic reticulum (ER) proteins (PubMed:9396746, PubMed:18287538).  Plays a role in the export of secreted proteins in the ER, the recognition of abnormally folded protein and their targeting to the ER associated-degradation (ERAD) (PubMed:9396746, PubMed:18287538).  Also serves as a cargo receptor for the export of transmembrane proteins (By similarity).  Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by stimulating the translocation of NDUFS4 and NDUFB11 from the cytosol to the mitochondria via interaction with TOMM40 (PubMed:31206022).  In response to ER stress, delocalizes from the ER-mitochondria contact sites and binds BCL2 (PubMed:31206022).  May be involved in CASP8-mediated apoptosis (PubMed:10958671).
What are the official names of this protein?
B-cell receptor-associated protein 31, BCR-associated protein 31, Bap31, 6C6-AG tumor-associated antigen, Protein CDM, p28.
What is the protein family that this protein belongs to?
Belongs to the BCAP29/BCAP31 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Note=May shuttle between the ER and the intermediate compartment/cis-Golgi complex (PubMed:9396746). Associates with the mitochondria-associated endoplasmic reticulum membrane via interaction with TOMM40 (PubMed:31206022).
Protein: NDK_SHEB8
Sequence: MAIERTFSIIKPDAVAKNHIGAIYNRFETAGLKIVASKMLHLTKEQAEGFYAEHSERGFFGALVAFMTSGPIMVQVLEGENAVLAHREILGATNPAQAAPGTIRADFAESIDENAAHGSDAVESAAREIAYFFSAEELCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_XANCB
Sequence: MAVQKSRVTPSRRGQRRSHDALTAKQLSTDPTSGEIHLRHHITADGYYRGKKVITTKSSAVQED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: OTC_VIBCH
Sequence: MAFNLRNRNFLKLLDFTPKEIHFLLDLSAELKRAKYAGTEQKTLQGKNIALIFEKSSTRTRCAFEVAAFDQGAQVSYIGPSGSQIGHKESMKDTARVLGRMYDGIQYRGFGQEIVEVLGQYAGVPVWNGLTDEFHPTQILADLLTMQEYGRSKQLHEMKFAYLGDARNNMGNSLMVGAAKMGMDIRLVAPKAYWPNDALVATCQEIAKQTGAKITLTEEVQEGVKGCDFLYTDVWVSMGEAADAWDERVALMKPYQVNMDVIKATGNPQVKFMHCLPAFHDDQTKVGQEIAAKYGMQGLEVTEEVFESEYSIVFDEAENRLHTIKAVMVATLGQ
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y274_CHLMU
Sequence: MPSTVAPVKGPDHFLNLVFPERVFASYMSPLAQKHPKAALYIASLAGFIFGLLKLITFPVLCAAGLFVFPIKGIISSLCHRRLDACSGYMLATFLSLFSLALIIVGIVSCVAWAPEFIFPIISIGMALATTETCFQIYTHLFPALEHKPSSPLKIENTTTKLSRSSSAPDLSCPSLSTQPTSPNQSLSAYKKY
What are the official names of this protein?
Uncharacterized protein TC_0274.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0442/CT_006/TC_0274 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LSPA_BURCH
Sequence: MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGAAFGFLSTASGWQRWAFTALGVGATLVICFLLKRHGHQRLFSVSLALILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITVGAVLLIYDELRRVRGAR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PT1_STRSL
Sequence: MTEMLKGIAASDGVAVAKAYLLVQPDLSFETVTVEDTSAEEARLDAALAASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMTGQIKETIRAKQVNAEAALTEVTDMFIAIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPATINEESIVVAHDLTPSDTAQLNKKYVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITELVKDGDILAVSGITGEVVINPTEEQIAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAANIGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDDQYEAYKAVLEGMNGKPVVVRTMDIGGDKELPYFDLPKEMNPFLGYRALRISISETGNQMFRTQLRALLRASVHGKLRIMFPMVALLTEFRTAKGILEEEKAKLVAEGVAVADDIEVGIMIEIPAAAMLADQFAKEVDFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGEMAGDQTAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEVLELSKEYVNVD
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HM06_CAEEL
Sequence: MLIPSSSSIPSSLSASASDSEPSSLNGSGISDQNILPNYHLHHHLINENEMEAANYAQVIKPTCEAFQDWPHTPMLYQQPQLHFMLPQHDWAYPHLAQSLPPPHHLTPSTAAVAAATIASQSSIINQTSVVTSTPSCQIKQEVERPEIIQRLMPPWPPAYQFSCDDSGSVSGAGGPHQPLSDISDDSEQTCPDDLEGFAKQFKQRRIKLGYTQADVGVALGTLYGNIFSQTTICRFEALQLSFKNMCKLKPLLFKWLEEADSTTGSPNSTFEKMTGQAGRKRKKRTSIEVNVKSRLEFHFQSNQKPNAQEITQVAMELQLEKEVVRVWFCNRRQKEKRIAPNQYDAPHPMALNNGYPMTADLFPYQAVVNHYTQQSPRQQ
What is the function of this protein?
Vital for embryonic development and essential for the proper function of the excretory cell (PubMed:11171402).  Required for the transdifferentiation of the Y rectal epithelial cell to the PDA motor neuron during larval development (PubMed:22493276).
What are the official names of this protein?
Homeobox protein ceh-6.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.