PharMolix/UniProtQA huggingface dataset:
Protein: RABL3_BOVIN
Sequence: MASLDRVKVLVLGDSGVGKSSLVHLLCQNQVLGNPSWTVGCSVDVRVHDYKEGTPEEKTYYIELWDVGGSVGSASSVKSTRAVFYNSVNGIILVHDLTNKKSSQNLYRWSLEALNRDLVPTGVLVTNGDYDREQFADNQIPLLVIGTKLDQIHENKRHEVLTRTAFLAEDFNAEEINLDCTNPRYLAAGSSNAVKLSRFFDKVIEKRYFLRDGNQIPGFPDRKRFGGGTLKSLHYD
What is the function of this protein?
Required for KRAS signaling regulation and modulation of cell proliferation (By similarity).  Regulator of KRAS prenylation, and probably prenylation of other small GTPases (By similarity).  Required for lymphocyte development and function (By similarity).  Not required for myeloid cell development (By similarity).
What are the official names of this protein?
Rab-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: RPOC1_TUPAK
Sequence: MSSDLKYSLSSEPPQPQVQSPLLKILKGEVSETTELKKLHSFRLCLSSPKIIKQWAQRTLPNGEIVGSITNAQTVNYKTLKPEKGGLFCERVFGPVKDFYCSCGKQKTKQHPKVCPTCGVQYISSQSRRYKMGYIELVSPVTHIWYLKSSPSYISLLLNLKKKNLEALTYCSENLSLNIKSFQNELLFQNVLHLLKANPFALEKGLKKRKKRFLVNSNWFSFIFDNSYLIKANSGFQLKVKDFPFFLITKNQNLQNFMGVCSQSANGNEQILPEMEKQGKNTFQFSPFLTTVQKHGSSENGSFPELKREKDELELFKLIDSFSSKSPSKKKDFFRSEILTAFYKKYSKFHFSRFRSNKKSFLISLFSSSNNWYFNKNQNIGYFSIFNKNFKIFFSLLNYQILLKTIDKNSLANLLSPLFDNYLNDDSQVLFDDSIKKLNLTKNFRSNEDQELSTLLNSCFFLNKIGAIAQSPFSLAFYTQKSEKFYCFSPSFLNPFEKDSLSGKIFSLKKKKILPSQKMFELKPLTLFCSKKTKRNEVESENPNSNHMLPFIAFSKKQRCEEKADFFKQLRMIELESEKSRSPKDLLFLNKFPFKNEKKLKYNLQKRNKLHTLKNPIGNFKFRKYFSLRLDSSLKRSLLIYQIKNFKNGFEHSDFYSENQTSTNFTKFLVSRELEKSSKFSNSLFSFENFAQLLIFIFDFPAALERQRQSFSLRSYSKSANFRSQTSARGEVGGNFNLEVKQSQNYFLDWKLTNNYRNFYQSSEIQNLNCFFISNFLVKNAIPVSPLSLEQFVFNNETQKNLHLGNEDSRFFANLKKPIKKLGLLKNSFLAETLANAKANAHNLKENRTPVIQDKENESQTFSQLFFDQIDQKEGSSLKSKDLNFTNWNNKKITRFIELLEKTLFLKKPGLVNNYYTISQSLQWPCQKDWARFLNYMTNTADKTDSLIPSYLERGISFDLVLTGAGSIKKLLSLFTPMGKKASIEIVAKQINGTLLKLNRDIKRLEDFFKFEIFFIDDQEIIEKVFMKLVILRSLRSKALRRLKVLRPFKGSHVLPEWMVLSVLPILPPALRPIIPLDSQQVAVSDLNKLYQTVLFRNKRVQRFYNDYYSLNFSEEMRYAQRLLQEAVDALIENGKGDSAAITASNNRPLKSLSDMIKGKKGRFRQNLLGKRVDYSGRSVIVVGPKLRLHECGLPKEMAIELFQPFLIRRLIFKEVATNFISAKKLIKSNPESILDILREVMENRPVLLNRAPTLHRLGIQAFQPKLISGRAILLHPLVCAAFNADFDGDQMAVHIPLSFQACAEAWKLMGSRNNLLSPATGEPIILPSQDMVLGCYYLTTLDRVKIKQKLSQSSFLFPFLISKQGVHENLSTISSNSKGIENWILKKPSQKSEIRTLSSFYEINESERATFESKTNDTSILKLQDKKRRETLTFKRNRLSPVDTKLHLMDLSKNKNQNLFLNRFEKRANCKVWSDSNKYYSNWDQVLQSLNQQLIDLHSPIWLRWNFYFEFVLKKESFLEIRLDKYGNSVYINPNYQSYSNSKLEKIVFYIRTTPGRVLMNKLIFEALNKPSLKKSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MSRA_PSEPG
Sequence: MVLRSEILVNKNVMPTAEQALPGRETPMSLPEFHYVFEGTPLLGPFFEGAIDFAIFGLGCFWGAERRFWQREGVVSTVVGYAGGFTPHPTYEEVCSGLTGHTEVVLVVFDKDKVSYRELLAMFWELHNPTQGMRQGNDVGTQYRSAIYCTSPEQLEQAEASRDAFQAELSKAGFGEITTEIDQAPTVYFAEAYHQQYLAKNPQGYCGIGGTGVCLPPSLQGN
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: CTX_SEPES
Sequence: MMGTSRCVILLFALLLWAANAAPPEIHTTRPNVPEEIKRPNSTEIETPAVKQLETPSIFLLTTLEVAEADVDSTLETMKDRNKKNSAKLSKIGNNMKSLLSVFSVFGGFLSLLSVVTTTSDLQVISDMFTGVNRKLDQINDKLDKLDNSVELQGLLTNYIPWQYSVKNGIEKLIETYKKMVEETDMNKRRLMAENFILFFENNQIESNINNLIKLTTTTDAVHQNMLFNELLDEAGCDIIRLTRIYMHVRRIFYQGTQLVLAYNSFKQMDPPEMKKYLNALIFIRNMYQSRVWHCKETTIAQSKKDIKDIVKTNAKFGITTVLRKINSELSRKYPWYSWSIVTVKKMLANQRNSTLGNQFYEMEAVGPHGSNFVVIWQGFKEHSQCEDIQKANTIAVLTICKSCHQSHVFTPSNMLNKNTCPNNQYPQVKAFIDRREPFRDEIQRKKSDVFWVAAGFKAPGNPCNHGCNGHGECKVVPYTDQFQCFCHGNYEGKMCQKKIQMKRDISKLISDLQTGYKNAFNVPSLTNILIQGENLAKQLKKMIQRIDNQFELTHILVKYISDLQKLDYILKISFNYSKKKITVDAFSRRMKAFLSLNPVDFIFQQLSNAILAEGFTDIQGKDFFNTFKRMIASNRDACTAPYGNEATILLERLSRLDLTAAESILAYYSFESNYLNPANMKRMLENAKQLVRDSKRRMRSYARYWERTSCPPLNVTHLTQTGCGALLSFEGMKVKLSCDGGRAAVPQNIECVNVNGNLQWSATPKCESSWSRWSKWSACASTCGNATQSRRRRCLGQSESEKCIGPSKQVRKCFVEDCCQEKYGKFKCDNNKCISLSRVCDGNDDCRNAEDESKSRCKYLRSGDRIALRNMAYSQEWLSVQYTDAVQADLYYGRAYLNHCIKGDHVTSSEWNSCAGQSLLIYGNYENGKIGKAIRFGDKIAMYYRKTNYHYRWFICYPTYCMTYTCPKKAGSFTFGPNGGCDEYEFYIINYNDKLSRDPVKPGDVITLANNRGSVKGNGYNRNININDCTVKRAQDDRIECNANAWQIFIK
What are the official names of this protein?
SE-cephalotoxin, SE-ctx.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_UREPA
Sequence: MNLISKISPQNRILNRARLIAEEVLKKEEEYEHFSDQELINKSDDIIEYLANNNPLDDKLVEALCIIREVIYRVHNKRAFKVQIIGAIIVYFGDFAEMMTGEGKTLTLVLVAYLNALYKKGVHMVTVNEYLVKVGAEFATPVLNFLNMSVGQITANMNEYEKRNNYNCDITYTTNSELGFDYLRDNMVTNYANKVQRGLWFAIVDEGDSVLIDEARTPLIISGEPQEEIGNYVKADRFVKTLYPQDFTLDPESQSVALTESGVEKAQKFFNTKNYYNFENSDIIHKVTNALRANFTFFNGREYIVKKDDDGEDIIALVDQSTGRIMEGRSYSAGLQQAIQAKEQIKIEPENLTVATITYQSLFRLYKKLAAVSGTAITEAEEFLNIYNMVVVTIPTNKPIKRIDHPDYVFDNKRTKWKYVIADVIRRHENGQPILIGTASVEDSEILHQLLERVNIPHEVLNAKNHAREAEIIACAGEYKAVTIATNMAGRGTDIKLSPESLEAGGLCVIGTERSDSRRIDNQLRGRAGRQGDIGESRFFISMEDTLFSRFATDNLAKADDKLSEDVISTKFFTRLLNNTQKKVESLNYDTRKNLIDYDHVLSNQRELIYKQRDKILISSDNKDILYRMLDSVIDDLIYQSHNKPNEDIIDIKKLIDLATQNIFYDNYLNQDEYYGLKFEQIKTKLKKDCINFFEQKEQLMTPTIFNQILSEIMISNIDEEWTKHLDITSKIREGVNLRAYEQKAPLNIYVEDSDKLFEKLKHNVAWKTVCSIGKINYVHQDYSDLNSEFIVNDNEINENNNSIDFENFNESIPTDQTIQESFDDNQSDNEDDKNNN
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: GTR5_MOUSE
Sequence: MEEKHQEETGELTLVLALATLIAAFGSSFQYGYNVAAVNSPSEFMQQFYNDTYYDRNEENIESFTLTLLWSLTVSMFPFGGFIGSLMVGTLVNKLGRKGALLFNNIFSILPAILMGCSQIAQSFELIIISRLLVGICAGISSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQLFGLRSLLANEDGWPVLLGLTGVPAGLQLLLLPFFPESPRYLLIQKKDEAAAERALQTLRGWKDVHLEMEEIRKEDEAEKAAGFISVWKLFTMQSLRWQLISMIVLMAGQQLSGVNAIYYYADQIYLSAGVKSDDVQYVTAGTGAVNVFMTILTIFVVELWGRRFLLLVGFSTCLIACLVLTAALALQNTISWMPYISIVCVIVYVIGHALGPSPIPALLITEIFLQSSRPAAYMIGGSVHWLSNFTVGLIFPFIQMGLGPYSFIIFATICFLTTIYIFMVVPETKGRTFIEINQIFTMKNKVSDVYPKKEEELGALPHAILEQ
What is the function of this protein?
Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:12031501, PubMed:19091748).  Can mediate the uptake of deoxyglucose, but with low efficiency (By similarity).  Essential for fructose uptake in the small intestine (PubMed:19091748, PubMed:26071406).  Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (PubMed:19091748).  Required for the development of high blood pressure in response to high dietary fructose intake (PubMed:19091748).
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 5, Fructose transporter, Glucose transporter type 5, small intestine, GLUT-5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma. Note=Localized on the apical membrane of jejunum villi, but also on lateral plasma membranes of the villi (PubMed:18496516, PubMed:26071406). Transport to the cell membrane is dependent on RAB11A (PubMed:26071406).
Protein: DAPF_PSEPW
Sequence: MLLRFTKMHGLGNDFMVLDLVSQHAHIQPKHAKQWGDRHTGIGFDQLLIVEAPNNPEVDFRYRIFNADGSEVEQCGNGARCFARFVLDKRLTAKKRIRVETKGGIIELDVQNDGQVCVDMGPPRFIPAEIPFVADEQALNYPLEVDGELHSIAAVSMGNPHAVLRVDDIRTAPVHGLGPKIENHPRFPQRVNAGFLQVIDRHRANLRVWERGAGETQACGTGACAAAVAAISQGWMDSPVSLDLPGGRLNIEWAGPGTSVLMTGPAVRVYEGQVRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_METVS
Sequence: MISDNIKKGVIRSPNRALLKACGYTDEDMEKPFIGVVNSFTDVVPGHIHLRTLAEAVKNGVYANGGTPFEFNTIGICDGIAMGHEGMKYSLPSREIIADAVESMARAHGFDGLVLIPTCDKIVPGMIMGALRLNIPFIVVTGGPMLPGEFQGKKYELISLFEGVGQYQVGKISEEELKCIEDCACSGAGSCAGLYTANSMACLTEALGLSLPMCATTHAVDAQKVRIAKKSGSKIVDLVKQDIKPKDILTKEAFENAILVDLALGGSTNTTLHIPAIANEIENKFITLDDFDRLSDEVPHIASIKPGGEHFMIDLHNAGGIPAVFNVLKEKIRDTNTVSGKTTLEIAKEVKYINYDVIRKTEAPVHETAGLRVLKGNIAPNGCVVKIGAVNPKMYKHEGPAKVFNSEDDAISAILGGKIVSGDVIVIRYEGPSGGPGMREMLSPTSAICGMGLDDSVALITDGRFSGGSRGPCIGHISPEAMAGGLIAVINDGDTIKIDMIGKKINVELNNSEIENRLKSLKIPEPKVKTGYLSRYSRLVSSADEGAVLK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ENGB_STRPS
Sequence: MTMELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGRMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: DRE1J_ORYSJ
Sequence: MDVARDMEKNTTAMGQLMSSSATTAATATGPASPKRPAGRTKFQETRHPVFRGVRRRGRAGRWVCEVRVPGSRGDRLWVGTFDTAEEAARAHDAAMLALCGASASLNFADSAWLLHVPRAPVASGHDQLPDVQRAASEAVAEFQRRGSTAATATATSGDAASTAPPSSSPVLSPNDDNASSASTPAVAAALDHGDMFGGMRTDLYFASLAQGLLIEPPPPPTTAEGFCDDEGCGGAEMELWS
What is the function of this protein?
Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.  Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription (By similarity).
What are the official names of this protein?
Dehydration-responsive element-binding protein 1J, Protein DREB1J.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: MEND_STAA3
Sequence: MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEAHPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLIVLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETIDAIYYQMQIASQYLYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGLIIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVDFVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLMEDTTVNRVSWLEKWQCLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMPIRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLMSKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFKRFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RABX_DICDI
Sequence: MSKTNQNLTIDKVIDNNNNIYLLKLLMIGGDVCSKNGISMVEKFLKHDKNLIQVFDDYDSTDEYINFKMKLNEFSSIDTSNSINNGIIYSENNKNKNNNNNYNYNNNNYNNNNNNNNNNNNNNNNNNNNNNNNNNSNFKIQIQIKDLSDCYCDLKIQTIPSCFYRGIHGFIIVYDINDHIAYNNIPKWIEEINSFSMKNSKIIVVCNDSNSKTPNFSDSSSSSSSSSSSNIIPLNKNTKNKVVGGVGVDPILANKLFQSLSIPHFIVSVDTNENIKMAFNSLKTLIFENNPLFQFFKLQGDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNLNYLNNLNNLNNLNNENNINNNSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTYNNDLKTNKKSLEIKKHNSNIEKKEVKQNIKDKKNKNKNKNACTCNLM
What are the official names of this protein?
Ras-related protein RabX.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SYRM_BOVIN
Sequence: MACGFRRSIASQLSRVLDLPPENLIKSISAVPISRKEEVADFQLSVDSLLENNNDHSRPDIQIQAMRLAEKLKCDTVVSEISTGQGTVNFKINRELLTKTVLQQVIEDGSKYGLKSELFSGLPKKRIVVEFSSPNVAKKFHVGHLRSTIIGNFIANLKEALGHQVTRINYLGDWGMQFGLLGTGFQLFGYEEKLQSSPLQHLFEVYVQVNKEAADDKNVAKSAHEFFQRLELGDMQALALWQKFRDLSIDEYMRIYQRLGVHFDEYSGESFYREKSQEVLKLLDSKGLLQKTLKGTAVVDLSGNGDPSSVCTVMRSDGTSLYATRDLAAAIDRMEKYNFDKMIYVTDKGQKKHFQQVFQILQIMGYDWAERCQHVPFGVVQGMKTRRGDVTFLEDVLNEIRLRMLQNMASIKTTKELENPEETAEQVGLAALIIQDFRGFLLSDYQFSWDRVFQSRGDTGVFLQYTHARLHSLEETFGCGYLNDFNTACLQEPQSVSILQHLLRFDEVLYRSSQDLQPRHIVSYLLTLSHLAAVAHRTLHVRNSPPEVAGARLHLFRAVRSVLANGMKLLGITPVCRM
What are the official names of this protein?
Probable arginine--tRNA ligase, mitochondrial, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: CXPA_CONCF
Sequence: CKCPSCNFNDVTENCKCCIFRQP
What is the function of this protein?
Upon intracranial injection in mice, as25a (the toxin without the two 4-hydroxyprolines) provokes paralysis of the hind limbs and death with a dose of 240 pmol.
What are the official names of this protein?
Conotoxin as25a, As25b.
What are the subcellular locations of this protein?
Secreted.
Protein: GLMU_PSEU2
Sequence: MSLDIVILAAGQGTRMRSALPKVLHPVAGNSMLGHVIHSARQLSPSGIHVVIGHGADAVREQLSADDLNFVMQDKQLGTGHAVAQALPALTADTVLILYGDVPLIEVETLSRLLERVNPQQLGLLTVALDDPTGYGRIVRDDQNRVCAIVEHKDASDAQKAITEGNTGILAVPAAHLADWLGRLSNNNAQGEYYLTDVIAMAANDGLVVATEQPHDAMEVQGANDRKQLSELERHYQMREARRLMAAGVTLRDPARFDVRGEVIVGRDVLIDINVILEGKVVIEDDVVIGPNCVIKDSTLRKGVVVKANSHIEGAILGEGSDAGPFARLRPGSVLGAKAHVGNFVELKNANLGEGAKVGHLTYLGDAEIGARTNIGAGTITCNYDGANKHKTTLGADVFIGSNNSLVAPVDILDGATTAAGSTITQNVPAEQLGVARARQRNIEGWKRPVKISKD
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAC_BACLD
Sequence: MENVFDYEDIQLIPAKCIVKSRSECDTSVQFGGRTFKLPVVPANMQTIIDEKLAVSLAENGYFYVMHRFEPETRIDFIKDMKARGLFSSISVGVKDEEYAFIEELTRENLTPEYITIDIAHGHSNAVINMIQHIKKHLPDSFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTHGDIAKSVRFGATMVMIGSLFAGHEESPGATIEKDGKLYKEYFGSASEYQKGEKKNVEGKKMYVEHKGAIMDTLTEMEQDLQSSISYAGGNKLDAIRNVDYVIVKNSIFNGDQY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: HIS4_KLEP3
Sequence: MIIPALDLIDGTVVRLHQGDYGQQRDYGSDPLPRLQSYAAQGAEVLHLVDLTGAKDPAKRQIPLLKSLVAGVDVPVQVGGGVRTEADVAALLEAGVARVVVGSTAVKSPEEVKGWFKRFGPERLVLALDVRIDADGNKQVAVSGWQENSGVTLEELVESYLPVGLQHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDLKDIAALRGTGVRGVIVGRALLEGKFNVTEAIQCWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUC1_CAEEL
Sequence: MGLSPAAVLIFLLLGVSQTYAAFSCKDQSGNDVDWFAVYKMPIEKDDGSVTGLAGGVAWYYVDVNKKGTLTPSAKTLDDNDQAIAYTLQQYYDKQNDKTIFHVMYNDEPWGSKSTSGIKLEEILSNRVYSNYTHEDDSTSTAFGHTKGTIFFDGTSGVWLVHSVPLFPNPTKYEYPVSGHDYGQTMLCMTFKYAQLKSIGTQLFFNRPNIYSSNLPTNMAADNADLAKAIAGQYQKGQPFQSVIELETMAGYSFTNFAKSKEFNADLYDTLVAPTLKTDLVVETWRRGSEIPLDCKLTYHANDALSIHVGSTTAFSYTKDHSKMAHSADMTKPWVCIGDINRMTSQYVRGGGTTCISSSFLWKAYSVIATQNNCA
What is the function of this protein?
Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA.  Implicated in apoptosis.
What are the official names of this protein?
Deoxyribonuclease-2, Deoxyribonuclease II, DNase II.
What is the protein family that this protein belongs to?
Belongs to the DNase II family.
Protein: ORDA_ASPFN
Sequence: MIYSIIICAGALLGLWILEKLLAPKDTRPPLPPGPWRKPIIGNLTDFPPKGTPEWLFWAKHQERYGPMSSLEVMGQTIIMINDAQLGIEIMHKKSALSQMIPDAPFAHMAGWGMSLATERNRQAWKTIRANMKQEIGTRRAISTFHPKMEIGIRRFLLRTLDNPDDLRFHIRKEANAFMMDVAYGYTIAPHGKDELYDLTQQSVRQFSHIFSPGEWSVNFFPILRYVPSWFPGASFQIKAAEYKRTIERMTMVPYLWIKDQVARGCSRPSILLRLLQKGHYESGSHQEQVLVWTNAEFVMGGSDTTVSAVSSFFVAMALYPEVQRKAREELDRVVGPTTLATFEHRSQLPFIDALVKEVFRWHPASPLGAPHITQEDQIWDGYLLPKGALLLPNIWTFTHDPSVYHDPMVFKPERFLEGKDSPPETDPMKFVFGFGRRICPGRFVTDEKLFLIACHAVSCFFISPKDPGAPEPDWLPGVISQPGAFDLNVVPRSPAHEELIRSIETDHPWKNADATDISRFMARNQMI
What is the function of this protein?
Converts O-methylsterigmatocystin (OMST) to aflatoxin B1 and converts dihydro-O-methylsterigmatocystin (DHOMST) to aflatoxin B2 in the aflatoxin biosynthesis pathway.
What are the official names of this protein?
O-methylsterigmatocystin oxidoreductase, OMST oxidoreductase, Aflatoxin B synthase, Aflatoxin biosynthesis protein Q, Cytochrome P450 64.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: ERPA_ACIBC
Sequence: MNAQALVLTDNAANKVRQLRDSEGNDDLMLRVYVTGGGCSGFSYGFNFAESVNEDDAEFVNGDVKMLVDSLSYQYLVGSVVDYVEGLEGSRFIVQNPNATTTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: RAPZ_ECOSM
Sequence: MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKRERELTMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
What is the function of this protein?
Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ.  When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E.  Consequently, GlmZ is inactivated and unable to activate GlmS synthesis.  Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS.
What are the official names of this protein?
RNase adapter protein RapZ.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family. RapZ subfamily.
Protein: CH32_CHICK
Sequence: MALENPKMHNSEISQRLGAEWKLLSEAEKRPYIDEAKRLRAQHMKEYPEYKYRP
What are the official names of this protein?
SRY-related protein CH32.
What are the subcellular locations of this protein?
Nucleus.
Protein: MOBA_STAAC
Sequence: MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP65_CANAL
Sequence: MLFKSFVTFTVLANALAAPLAHQHHQHKEEKRAVHVVTTTNVVVVTIGNGDQTTTFAAPSVAAESSVSVSVNTEPPQNHPTTTQDVASASTYPSSTDGSAASSSAAASSSSQAGSEPSGGVGSGGAKGITYSPYSDNGGCKSESQIASEIAQLSGFDVIRLYGVDCSQVEAVLKAKTSSQKIFAGIFDVSSITSGIESLAEAVKSCGSWDDIYTVSIGNELVNAGSATPSQIKAYVEEGRKALKAAGYTGPVVSVDTFIAVINNPDLCDYSDYMAVNAHAFFDGHVVAENSGAWVLQQIQRVWTACGGKKNVLITETGWPSRGDSNGVAVPSKSNQQAAISSIKSSCGASAILFTAFNDLWKADGPYNAEKYWGIYSN
What is the function of this protein?
Surface mannoprotein required for hyphal morphogenesis, surface adherence, and pathogenicity.  Contributes in a high proportion to the carbohydrate component of the matrix due to high levels of glycosylation and may play important roles during biofilm development and maintenance.  Acts as a major antigen target of host cell-mediated immune response.  Induces extensive T-cell proliferation of human peripheral blood mononuclear cells.  Facilitates host dendritic cells maturation and promotes cytokine production through its glycosylated portion while its protein core is essentially involved in induction of T-cell response.
What are the official names of this protein?
Cell surface mannoprotein MP65, Mannoprotein of 65 kDa, Soluble cell wall protein 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Secreted, cell wall.