PharMolix/UniProtQA huggingface dataset:
Protein: NITR_PYRAB
Sequence: MVKVAYVQMNPQILEPDKNYSKAEKLIKEASKQGAQLVVLPELFDTGYNFETREEVFEIAQKIPEGETTTFLMDVARDTGVYIVAGTAEKDGDVLYNSAVVVGPRGFIGKYRKIHLFYREKFFFEPGDLGFRVFDLGFMKVGVMICFDWFFPESARTLALKGADVIAHPANLVMPYAPRAMPIRALENKVYTVTADRVGEERGLKFIGKSLIASPKAEVLSMASETEEEVGVAEIDLYLVRNKRINDLNDIFKDRREEYYFR
What is the function of this protein?
Nitrilase that hydrolyzes preferentially aliphatic nitriles like malononitrile and fumaronitrile in vitro.  These dinitriles are converted to the corresponding monoacid mononitriles, showing the enzyme is regioselective.  Cannot hydrolyze compounds with a nitrile group bound to an aromatic ring or amino acid.  Its biological role is unknown.
What are the official names of this protein?
Nitrilase, PaNit.
What is the protein family that this protein belongs to?
Belongs to the carbon-nitrogen hydrolase superfamily.
Protein: Y1885_ACAM1
Sequence: MYTIDISLRGTPLGLSVQRKESADAEALYQQVLAAIKSGNPTILEMTCDREPDKKAAVLVNEITAVQLSDKSGGAGAGRAAGFFELGA
What are the official names of this protein?
UPF0367 protein AM1_1885.
What is the protein family that this protein belongs to?
Belongs to the UPF0367 family.
Protein: TMCAL_STAAN
Sequence: MKSVGLITEYNPFHNGHQYHINQSKKLTNADVTIAIMSGNFVMRGEPAIYNKFTRAKMALSTADLVIELPATASLSSGDHFAELAVKVADYMSVDTIAFGSENNDIKTLKQLAHSINEIEQSESFSQKVKEGKSYPRIISELLEHHEALASPNNILGISYLKAIAKNAKNINAISIKRENAQHHDSLIQHHQFASGTSIRTSIISQDDHWHHVVPKDIQHLYVTPHITLNQIFPYLKYQIIAMTTDSLKNIYTVTEGFENRLKSNIYEATDFHHFVKLLKTKRYTYTHIQRLLMNVLLNIKPTDVTSNIHAVKVLAMNDRGRQYLKHLKTAFPERQYITNINKSNAHYFTNEIKATHIYNAISGQQQTDFNTPVIQQYR
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRP_ECO55
Sequence: MKKNQFLKESDVTAESVFFMTRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKPLEFSKPAAWQNDLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYAEQVASLYRGLDLRENF
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase catalytic subunit MsrP.
What is the protein family that this protein belongs to?
Belongs to the MsrP family.
What are the subcellular locations of this protein?
Periplasm. Note=Is attached to the inner membrane when interacting with the MsrQ subunit.
Protein: UGPA_SHIFL
Sequence: MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSSQFVGLDNFVTLFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSMVLMFLVIVLTVVQFRYVESKVRYQ
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
sn-glycerol-3-phosphate transport system permease protein UgpA.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. UgpAE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NTPPB_BRUA2
Sequence: MTVKLVLASKSPFRSALLKNAGIEFSTASADIDERAVEAPLYESGATPEDVAQILAEAKAIDVSEKNPGAVVIGCDQTLSLGDEIFHKPHDMEAARRQLQKISGKTHQLNSAVVLARDGKTLWRHVSIAHMTMRDLDAGFIGRYIGRVGDIALSSVGAYQVEGPGIQLFEKIDGDYFTIVGLPLLPLLAELRREKCIDG
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_HAEIN
Sequence: MMTSNSYWQRLKVAFQYVMPQIYLTQIAGWFAKQKWGKITHFVIKAFAKKYNIDMSIAQKEQFSDYASFNEFFIRPLKENARPINQNPTALCLPADGRISECGHIDDNLLLQAKGHFFSLEDLLAEDKELVETFKNGEFVTTYLSPRDYHRVHMPCDATLRKMIYVPGDLFSVNPFLAQHVPNLFARNERVICVFDTEFGTMVQILVGATITASIGTTWAGVINPPRHNEVKTWTYEGESAVKLLKGQEMGWFQLGSTVINLFQANQVRLADHLSVNEPVRMGEILAYKK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BP11B_CROAD
Sequence: QGGWPRNPIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 11b, BPP-11b.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGB_SHEPW
Sequence: MNFENLLIEVGTEELPPKSLRKLAESFLNNFTDELKKAELTFESAVWHAAPRRLAINVNQLALAQADKVVEKRGPAVAQAFDADGNPTKAAMGWARGNGITVEQADRLKTDKGEWLLHQAKVVGVETKSLIAAMAQRSLDKLPIPKPMRWGSNTTQFIRPVHTVTMLLGSEVVEGELLGIKSDRIIRGHRFMGKPSIELDHADNYLSVLKEQGKVDANYEARKAQIKADAEAAAAKLGGVADLEDDLLEEVTSLVEWPVVLTASFEEKFLDVPAEALVYTMKGDQKYFPVFDDAGQLLPNFIFVTNIESKDPQQIISGNEKVVRPRLADAEFFFETDKKNSLESRLSSLETVVFQKQLGTIKQRVERISAMAAYIATSIGANSEEAARAGLLSKSDLMTNMVMEFTDLQGTMGMHYARLNGETEAVAVALSEQYKPKFSGDTVPTAPVSICVALAEKLDTLVGIFGIGQAPKGAADPFALRRAAIGVLRICLENNLPLDLVDLIAKAQELHGENLTNDKAPEQVLEFFMGRFRAWYQDQGISVDVILAVLARRPTAPADFESRIKAVAHFRTLEQALALAAANKRVSNILAKVEGELPATIDEALLVEAAEKALAAKLAELQPQLAPLFAAANYQEALALLASLRESVDTFFEDVMVMADDEALKNNRLALLSSLRDQFLHAADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_MYCPN
Sequence: MEPKIRRILNKELQRQRDCICLIASENYVSRDILEVTGSILTNKYAEGYPTRRFYEGCEVVDESESLAINTCKELFGAKWANVQPHSGSSANYAVYLALLKPGDAILGLDLNCGGHLTHGNKFNFSGKQYQPYSYTINPETEMLDYDEVLRVAREVKPKLIICGFSNYSRTVDFERFSAIAKEVGAYLLADIAHIAGLVAAGLHPNPLPYTDVVTSTTHKTLRGPRGGLIMSNNEAIIRKLDSGVFPGCQGGPLQHVIAAKYVCFKEALQPKYKQYIQNVKTNAASMASWFKQQGYRVISNGTDTHLFSLDVGKGKDVSQWLQQANIVLNMNTVPFDKNPAINPSGIRIGTPAMTTRGFKEKHFLYVAALIDKIIKSDGNKKVIKEVKKAVLKLLERFPLYKGLEY
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U496C_ORYSJ
Sequence: MGATFRCFGGCVKPDDQQVHEPKKVVAPSSSFDFREEYTSAFRTESYNDFWARVLDITLAHGAALVPRHGGGGGCAASKRLPSYRLFAEHLLEPDQRAVAAALASPRGSRLRPDVRGLLAAYYAETANASFLCSHLLKDIEHIRLRYRPLKHTLRKLASDVGVSGLADVSAALGQPFTALAASQGRLREVQAGSGDLLRGLDAGRKKARHRIRSVARLRRALSVSFVTAVAVVAVVGACIGVHILAAFAAFPMMSPAWLGERFFSGRAARRALVQLEAAAKGTYILNRDMETISRLVARVRDEGEHMVALRRLCVEHRPAAGAGGKGRLVQEVLRQLSKNEESFRQQLDELEEHLFLCFMTTNKARIMVMNFMAAAAR
What are the official names of this protein?
UPF0496 protein 3.
What is the protein family that this protein belongs to?
Belongs to the UPF0496 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL9_SYNJB
Sequence: MQVVLRQAIPGLGKPGEIVNVKPGYARNYLFPRQMAVRVTPGILKEQQVRLEQEAARKLAERQQAENYKTALETIGRFVIRKKVGEHDLLFGQVTTSDIAEVVLATSGLDIDRRNILLNEEIKKTGVYPVQVKLHPEVTATLRIQVTPE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: LTOR4_BOVIN
Sequence: MTSALTQGLERIPDQLGYLVLSEGAVLASSGDLENDEQAASAISELVSTACGFRLHQGMSVPFKRLSVVFGEHTLLVTVSGQRVFVVKRQNRGREPIDV
What is the function of this protein?
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids.  Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag.  Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity).
What are the official names of this protein?
Ragulator complex protein LAMTOR4, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 4.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR4 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PNP_PSEA7
Sequence: MNPVTKQFQFGQSTVTLETGRIARQATGAVLVTMDDVSVLVTVVGAKSPAEGRDFFPLSVHYQEKTYAAGRIPGGFFKREGRPSEKETLTSRLIDRPIRPLFPEGFMNEVQVVCTVVSTNKKSDPDIAAMIGTSAALAISGIPFAGPIGAARVGFHPEIGYILNPTYEQLQSSSLDMVVAGTEDAVLMVESEADELTEDQMLGAVLFAHDEFQAVIRAVKELAAEAGKPAWDWKAPAENTVLVNAIKAELGEAISQAYTITIKQDRYNRLGELRDQAVALFAGEEEGKFPASEVKDVFGLLEYRTVRENIVNGKPRIDGRDTRTVRPLRIEVGVLGKTHGSALFTRGETQALVVATLGTARDAQLLDTLEGERKDAFMLHYNFPPFSVGECGRMGSPGRREIGHGRLARRGVAAMLPTQDEFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPVKAPVAGIAMGLVKEGEKFAVLTDILGDEDHLGDMDFKVAGTDKGVTALQMDIKINGITEEIMEIALGQALEARLNILGQMNQVIARPRAELSENAPTMLQMKIDSDKIRDVIGKGGATIRAICEETKASIDIEDDGSVKIYGETKEAAEAAKQRVLAITAEAEIGKIYVGKVERIVDFGAFVNILPGKDGLVHISQISDKRIDKVTDVLQEGQEVKVLVLDVDNRGRIKLSIKDVAAAEASGV
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_BACAN
Sequence: MRLRHKPYAMDRINEYSHIVIGNPEERAGNWKEVFGNEQPIHIEVGTGRGRFMYDMAKANPHINYIGIEKFTSVVVDALDKLIEEELPNLKLINKDAEDLTVFFAKGEIDRVYLNFSDPWPKKRHTKRRLTYKTFLRNYEEVLVEGGEIHFKTDNQGLFEYSLMSMAEYGMLLTYLSLDLHNSDFEGNIMTEYEEKFSSKGHRIYRVEAKYRTEPMQ
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: MBD6_HUMAN
Sequence: MNGGNESSGADRAGGPVATSVPIGWQRCVREGAVLYISPSGTELSSLEQTRSYLLSDGTCKCGLECPLNVPKVFNFDPLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPAKNKRRKLAP
What is the function of this protein?
Binds to heterochromatin.  Does not interact with either methylated or unmethylated DNA (in vitro).
What are the official names of this protein?
Methyl-CpG-binding domain protein 6, Methyl-CpG-binding protein MBD6.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with pericentric heterochromatin in about 25% of the cells.
Protein: RL27_RICCK
Sequence: MATKKAGGSSRNGRDSAGRRLGVKQSDGQYVIPGNIIVRQRGTKIHPGRNVGLGKDHTIFALIEGRVEFVTKRNHKVVNVKEIASA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: EFTS_CERS5
Sequence: MAITAQMVKELRESTGAGMMDAKKALTETDGDMEAAVDWLRTKGLAKAAKKAGRTAAEGLVGVAVSGGTGVAVEVNSETDFVAKNADFQTMVTGFTQAALSVDDVEALKAADMGGKTVETTLQETIAVIGENMTLRRMAKISGDSVAAYVHNAAADGLGKIGVLVAVKGADNGIAKQIAMHIAATSPMALSEADLDPTLVERERAVQTQKALEENAASAKPKPDSVIENNIIPGRMKKFLEENTLLGQKFVINPDVTVAEAAKQAGVEILGFVRMAVGEGIEKEKEDFAAEVAKTLAG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y390_STRGC
Sequence: MDIRQVTETIAMIEEQNFDIRTITVGISLLDCIDTDINRAAEKVYQKITTKAKNLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDAKDYIPLAKALDRAAKEIGVDFIGGFSALVQKGYQKGDEILINSIPKALAETDKVCSSVNIGSTKTGINMTAVADMGRIIKETAQLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVVINVGVSGPGVVKRALEKVRGESFDVVAETVKKTAFKITRIGQLVGQMASERLGVKFGIVDLSLAPTPAVGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDEGMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEATPAETIAAMIADEAAIGVINQKTTAVRIIPKGKEGDMIEFGGLLGTAPVMKVNQASSAAFIARGGQIPAPIHSFKN
What are the official names of this protein?
UPF0210 protein SGO_0390.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RS19_STRP4
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: LANA_STRMD
Sequence: MMNATENQIFVETVSDQELEMLIGGADRGWIKTLTKDCPNVISSICAGTIITACKNCA
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria.  Macedovicin inhibits a broad spectrum of lactic acid bacteria, several food spoilage species (e. g.  Clostridium spp. ) and oral streptococci (PubMed:23122510).  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.
What are the official names of this protein?
Lantibiotic macedovicin.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
What are the subcellular locations of this protein?
Secreted.
Protein: TCPD_CANGA
Sequence: MVAQKSVSNATFKNKEKPQEVRRANIVAARAVADAIRTSLGPKGMDKMIKTSRGEIIISNDGHTILKQMAILHPVAKMLVDVSAAQDSEAGDGTTSVVILTGALLGAADRLLNKGIHPTIIAESFQKAARRSVETLLEICHPVSLDDREDLIRAASTSLSSKIVSQYSSFLSPLAVDAVLSITEKDSKTVDLNDIRLVKKVGGTIGDTEMVDGVVLTQTVVKTAGGPTMKEKAKIGLIQFQISPPKPDTENNIVVSDYRQMDKILKEERAYLLNICKKIKKAKCNVLLIQKSILRDAVNDLALHFLAKLGIMVIKDIEREEIEFLSKSLGCKPISDVELFTEDRLGSADLVEEIDSDGTKIVKFSGVKGVNAKPTVSVIIRGANSMILDETERSLHDALCVIRCLVKERGLIAGGGAPEIEISRRLERESRSMEGVEAYIWQEFAQALEVIPTTLAENAGLNSIKVITELRSRHENGDVNEGISVRRSGTTNTYEEHILQPVLVSTSAITLASECVKSILRIDDITFSR
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_RICCN
Sequence: MYINYLKDLIGFKSVTPKSDGAIEYINDLLKQHGFKTEIKIFGDSKSEQVTNLYAVFGSNEPNICFVGHVDVVLAGNHELWHNASPFKVSQQDGKIYGRGAVDMKGAIACFLAASLDFIKNNTDFKGSISFLLTSDEEGKAKHGTKEMLQYIYDQGYKINFAIVGEPTCEKEIGDAIKIGRRGSVNFKLNIEGLSGHVAYPHKANNPLPCLIIILNELTNIKLDEGTEFFQRSNLEVTNIEVSNNTSNVIPASTEASFNIRFNNLHSAETLAKQVEEIIKQHCKEYKVDYKLEYSSSAESFIQNPSDKIKEFAKVVEHTLKIKPEFSTSGGTSDARFVKNYCPLVEFGLLSETAHKINEYTKISDLQKLYDVYYNFLMEIL
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: TSAB_HAEIN
Sequence: MQNLTLLALDTSTEACSVALLYRGEKTHINELAQRTHTKRILPMIDEILANSGLGLNQVDALAFGRGPGSFTGVRVGAGIAQGLAFGADLPVIPISNLTAMAQAAFELHQAENVVAAIDARMNEVYFSQVVREKVRSDFGEFFQWREIISEQVCSPEQAINQLQNDNAFRVGTGWAAYSQFTEKNLTGSDIALPNALYMLELAQVEYLQKHTISALEIEPIYLRNEVTWKKLPGRE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro.  TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaB, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaB.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family. TsaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARAD_ECOLI
Sequence: MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDAAQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
What is the function of this protein?
Involved in the degradation of L-arabinose (PubMed:13890280).  Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase AraD, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: SYP_UREPA
Sequence: MSKKLEKITTRKENFADWYTSIVNNAKLIQYTDIKGMMVFQPNAWAIWEAIKNQIDVEFKKHGVRNLAMPTLIPLSEFQKEKDHIEGFAPELFMVNQIGDKKLDNSYAIRPTSEILFCNYFKNIVNSYNDLPIKNNQWCSVMRAEKTTRPFLRNAEFHWQELHAIFASENEADSFAKVILDVYTDFVQNYLCIPVIKGLKTPWERFAGAQKTYTIEAMMQDGQALQSATSHYLGQFFAKAYDIKFQGQDNQMHYVHQMSAGLSTRIIGALIMVHADDQGLILPPDIAFNQIAILTIFSNKNPQLLKISQQICEQLNNYRLFEDHSDKGIGYKLAQQEIEGTPICILVGAKELVNQQVVIVRRDTHEKINVDLTDLKLIIPKLLADIKRNIYEKAKKDLEDSIVFVNNIEELKQVIAQNKMAKAFFDGTKEDDEQIKLLTNASTRCIFDETQNGQCFYTNKKTNKLTLFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_ECO45
Sequence: MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: STAP2_HUMAN
Sequence: MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPKVFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH
What is the function of this protein?
Substrate of protein kinase PTK6.  May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
What are the official names of this protein?
Signal-transducing adaptor protein 2, STAP-2, Breast tumor kinase substrate, BRK substrate.