PharMolix/UniProtQA huggingface dataset:
Protein: CADH2_MOUSE
Sequence: MCRIAGAPRTLLPLLAALLQASVEASGEIALCKTGFPEDVYSAVLPKDVHEGQPLLNVKFSNCNRKRKVQYESSEPADFKVDEDGTVYAVRSFPLTAEQAKFLIYAQDKETQEKWQVAVNLSREPTLTEEPMKEPHEIEEIVFPRQLAKHSGALQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQPPTGIFIINPISGQLSVTKPLDRELIARFHLRAHAVDINGNQVENPIDIVINVIDMNDNRPEFLHQVWNGSVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRILSQAPSTPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGEVPENRVDVIVANLTVTDKDQPHTPAWNAAYRISGGDPTGRFAILTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTATVSVTVIDVNENPYFAPNPKIIRQEEGLHAGTMLTTLTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQEAETCETPEPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTINRLNGDFAQLNLKIKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRLDERPIHAEPQYPVRSAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGDQDYDYLNDWGPRFKKLADMYGGGDD
What is the function of this protein?
Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion by dimerization with a CDH2 chain from another cell (PubMed:2762814, PubMed:11433297, PubMed:17988630, PubMed:9655503, PubMed:25253890).  Cadherins may thus contribute to the sorting of heterogeneous cell types.  Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence (PubMed:24952463).  Plays a role in cell-to-cell junction formation between pancreatic beta cells and neural crest stem (NCS) cells, promoting the formation of processes by NCS cells (PubMed:26750727).  Required for proper neurite branching.  Required for pre- and postsynaptic organization (By similarity).  CDH2 may be involved in neuronal recognition mechanism.  In hippocampal neurons, may regulate dendritic spine density.
What are the official names of this protein?
Cadherin-2, Neural cadherin, N-cadherin.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell membrane, sarcolemma. Cell junction. Cell surface. Note=Colocalizes with TMEM65 at the intercalated disk in cardiomyocytes (PubMed:26403541). Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes (PubMed:23392350).
Protein: DDL_NOCFA
Sequence: MTNRIRVAVVFGGRSNEHAVSCVSAGSVLRHLDPTRYEAVPIGITPQGGWVLANSDVAAIGLSHEALPSVDAGGTALTLTADPTRGGELVALDDAGAVLGTVDVVFPILHGPFGEDGTLQGMLELAGVPYVGPGVLASAAGMDKEFTKKLLAAEGLPVGTQVVLRPGTATLTEEQRERLGLPVFVKPARAGSSIGITKVDDWAALDTAIAAAREHDPKVIVEAGIVGREVECGVLEFPDGRISASVLAEIRMPEGDGPQFYDFDTKYLDDVCEFDVPAKLDDDIAEQVRELAVRAFQALDCQGLARVDFFVTADGPVINEINTMPGFTSISMYPRMWEATGIDYGTLVSTLIETALARGTGLR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BORPA
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTRAGRAILNARRAKGRKRLAV
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: AROE_ECODH
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLMRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALSMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: GLYM_CANGA
Sequence: MMLLRAARVPVLGRRFLSQQQLISKHVQEVDPEMFRILSDERSRQKHSVTLIPSENFTSKAVMDLLGSEMQNKYSEGYPGERYYGGNQFIDKAESLCQARALDLYGLDPEKWGVNVQALSGAPANLYAYSAVMEVGDRLMGLDLPHGGHLSHGYQLPSGTKISYISKYFNTMPYHVNTETGIIDYDTLAMTSKLFRPKVIVAGTSAYSRKLDYARFRKIADGCGAYLLSDMAHISGLVAANVIDSPFEHSDIVTTTTHKSLRGPRGAMIFYRKGIKKVNKKTGKETPFTFDKTINFSVFPGHQGGPHNHTISALAVALKQAKTPEFVEYQKQVVSNAKAFGDELLKRGFELVSGGTDNHLLLLNLSNMGIDGARLEAILEKINIAANKNTIPGDKSALFPSGLRVGTPAMTTRGFQEQDFKKVAEYIDNAVKLSIALKSQESADAKDVRSKLNSFKQLCDQSEPVQKLAEEVSSWVGTFPVPGEL
What is the function of this protein?
Interconversion of serine and glycine.
What are the official names of this protein?
Serine hydroxymethyltransferase, mitochondrial, SHMT, Glycine hydroxymethyltransferase, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TWF_AEDAE
Sequence: MSHQTGIKANAELLKFFGKCKDGKTRVLKVSIENEELALVDHKAVKKDWEKDYDALVKPLVEDDVPCYILYRLDYKIPTGYAWLLLSWVPEAATVRQKMLYASTKATLKLEFGSSNIKEEINATTKEETTLKGYQKHKIDFSAPAPLTSREEELAEIRKSEVKTDFGIDTKQQTLGGINCPISDPTSQALIDMRRGAYNYLQFRIDLEEEKIHVVNAANIDILKLPSQIPKDHARYHLYLFKHQHEGNHLDSVVFVYSMPGYTCSIRERMMYSSCKGPFSATIEKHGIEITKKIEIDNGEELTEEFIYEELHPRKLNLRPQFSKPKGPPSRGAKRLTKPQAVE
What is the function of this protein?
Actin-binding protein involved in motile and morphological processes.  Inhibits actin polymerization, likely by sequestering G-actin (By similarity).
What are the official names of this protein?
Twinfilin.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: PGLRE_ASPNC
Sequence: MVTSSSVIVLTLWAALVSASPVADPLVTPAPKLEDLEKRATSCTFSGSEGASSASKSKTSCSTIVLSDVAVPSGTTLDLTDLNDGTHVIFEGETTFGYEEWSGPLVSVSGTDITVTGADGAYLNGDGSRWWDGEGSNGGKTKPKFFYAHDLTSSTISGIYIQNSPVQVFSIDGSTYLTMEDITIDNTDGDDGEAANTDGFDIGDSTYITITGANVYNQDDCVAVNSGENIYFSGGVCSGGHGLSIGSVGGRSDNTVKNVTFYDSEIKSSQNGVRIKTIYGDTGSVSEVTYKEITLSDITDYGIVVEQNYDDTSKSPTDGITIEDFVLDNVQGSVESSGTNIYIVCGSDSCTDWTWTDVDVSGGKTSSDCENVPDDISC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall (By similarity).
What are the official names of this protein?
Probable endopolygalacturonase E, PGE, Pectinase 4, Pectinase E, Polygalacturonase E, Polygalacturonase IV, PG-IV.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DYR_YEAST
Sequence: MAGGKIPIVGIVACLQPEMGIGFRGGLPWRLPSEMKYFRQVTSLTKDPNKKNALIMGRKTWESIPPKFRPLPNRMNVIISRSFKDDFVHDKERSIVQSNSLANAIMNLESNFKEHLERIYVIGGGEVYSQIFSITDHWLITKINPLDKNATPAMDTFLDAKKLEEVFSEQDPAQLKEFLPPKVELPETDCDQRYSLEEKGYCFEFTLYNRK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: AT8B2_HUMAN
Sequence: MTVPKEMPEKWARAQAPPSWSRKKPSWGTEEERRARANDREYNEKFQYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNNIRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVGNGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRKKQKAQHRCMRRVGRTGSRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSWIESLRRKKSDSASSPSGGADKPLKG
What is the function of this protein?
Catalytic component of P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of phosphatidylcholine (PC) from the outer to the inner leaflet of the plasma membrane.  May contribute to the maintenance of membrane lipid asymmetry.
What are the official names of this protein?
Phospholipid-transporting ATPase ID, ATPase class I type 8B member 2, P4-ATPase flippase complex alpha subunit ATP8B2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Efficient exit from the endoplasmic reticulum requires the presence of TMEM30A or TMEM30B.
Protein: OPGD_ECOUT
Sequence: MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQRFDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLDAQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAGFRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFWFDTVKPGATTFTVYALLDSASITGAYKFTIHCEKNQVIMDVENHLYARKDIKQLGIAPMTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNPKGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVCFWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEKWARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSDSTDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS
What is the function of this protein?
Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs).
What are the official names of this protein?
Glucans biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the OpgD/OpgG family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CSLC8_ARATH
Sequence: MAPRFDFSDLWAKETRRGTPVVVKMENPNYSIVEVEEPDSAFQPMEKSRGKNAKQVTWVLLLKAHKAVGCLTWVATVFWSLLGSVKRRLSFTHPLGSERLGRDGWLFSAIKLFLVASLAILAFELVAYYRGWHYFKNPNLHIPTSKLEIQSLLHLFYVGWLSLRADYIAPPIKALSKFCIVLFLVQSVDRLILCLGCLWIKFKKIKPRIDEEHFRNDDFEGSGSEYPMVLVQIPMCNEREVYEQSISAVCQLDWPKDRLLVQVLDDSDDESIQELIRDEVTKWSQKGVNIIYRHRLVRTGYKAGNLKSAMSCDYVEAYEFVAIFDADFQPNSDFLKLTVPHFKEKPELGLVQARWAFVNKDENLLTRLQNINLCFHFEVEQQVNGVFLNFFGFNGTAGVWRIKALEESGGWLERTTVEDMDIAVRAHLHGWKFIYLNDVKVLCEVPESYEAYKKQQHRWHSGPMQLFRLCLRSILTSKIAMWKKANLILLFFLLRKLILPFYSFTLFCVILPITMFVPEAELPIWVICYVPIFMSLLNILPAPKSFPFIVPYLLFENTMSVTKFNAMVSGLFQLGSSYEWIVTKKAGRSSESDLLALTDKESEKMPNQILRGVSDSELLEISQVEEQKKQPVSVKKTNKIFHKELALAFLLLTAAVRSLLASQGVHFYFLLFQGLTFLLVGLDLIGEQMS
What is the function of this protein?
Probable beta-1,4-glucan synthase rather involved in the synthesis of the xyloglucan backbone than cellulose.  Seems to work simultaneously with xyloglucan 6-xylosyltransferase.  Xyloglucan is a noncellulosic polysaccharides of plant cell wall and consists of a glucan backbone substituted by xylose, galactose and fucose.
What are the official names of this protein?
Probable xyloglucan glycosyltransferase 8, Cellulose synthase-like protein C8, AtCslC8.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. Plant cellulose synthase-like C subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: NUOD_GEOSL
Sequence: MASTEIMTVNMGPQHPSTHGVLRMVIELDGEVIQKITPHIGYLHRGVEKLSEHRTYHQTIPLTDRLDYLAPMSNNLGYVLAVEKLLGIEIPERAQTIRVIMAELTRLKSHLVWIACHALDIGAMTVFIYAFREREMIMSLYEKISGARMTSNYFRVGGLSSDVYDGFEKDVREVIDTFPGHFDTYEGLLTKNTIWVNRTVGNGVISAEDAVDYGITGPALRGSGVDWDLRRDNPYSGYEKYSFKVPVGEKCDTFDRYKVRLIEMREAVNIIRQALDSLKPGPVLADNPQVTYPPKENVYNSIEGLIHHFKIASEGFPVPEGEVYQSVEAPKGELGYYIVSDGGPKPYRMRIRPPSFVNLGAIEKMAKGSMIADLVAVIGTLDIVLGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IOLN_THEMA
Sequence: MERPTGVYFQTMTMKQIRERLKQCDLIIIPVGSTENHGPNAPTGEDTFLVTRMAEQVALKTGCTVAEPIWYGYHPYHHIGMPGTVPVKDEAFIDYLVSVIAGFWNTGFRKQILLNGHGQEFVIPIAIHKFAKIFQVPAIIINLNWYHAIQDKFKTKEEGGPYETPFIHADEVETSWSLALFPEFMHQEWAVDTEPKGFLPEGHIDKAGNLLHRPIAWYGHVGGGPIEVVAYPEGVVGKATLASAEKAKEGVEALLDYLEKLVRDIMERFPAGKLPPAEMLSQRPKEELEALTKEPLTEGWRNLYTAGNLWG
What is the function of this protein?
Catalyzes the ring-opening hydrolysis of 3-dehydro-scyllo-inosose (diketo-inositol) to 5-dehydro-L-gluconate, and thus probably functions in a myo-inositol degradation pathway together with IolG, IolM and IolO.
What are the official names of this protein?
3-dehydro-scyllo-inosose hydrolase, Diketo-inositol hydrolase.
What is the protein family that this protein belongs to?
Belongs to the creatininase superfamily.
Protein: LDB17_ASHGO
Sequence: MALKPPYSPESGGASRSRTQTETVHFWEYLESLLDAADCTSEAQVNSALVAYVKTASERYGEYLVEDRDFYRVALLLLRAPLYERNKSFCISKMLSLLSIDLLEMSMKFVISYILLCECKADSSSLDHVLDYQGFTVIYNKLYEHFAYLHRYSDDEETTFEANITELDEEINEELRKISTVLLDLLFQILKYSKCELANLQRVDDFFVYYMMVSLRSDTVEDMYNNAKFRLLLALNEQYMISNHKAGLENKVYAYLMNHTASKQFVELLLLQFNRTVDKSLQIMMCKIIYLILTSRDEIAMDYFYLNDLHVVTDVLIRNLTNISEDEEVLRNTFLRILDLILRKTEWTQSHYREQELLELLEYLCSVDNLCSSGNVKSEHMSTTKLAFKCRQAIRQLKVEQKKSRDAAAAPAPRPKTPEPRFERTDSHMSVPMDKITRAIGRSPFASPPPPPPSRRV
What is the function of this protein?
May be involved in protein-linked oligosaccharide phosphorylation.
What are the official names of this protein?
Protein LDB17.
What is the protein family that this protein belongs to?
Belongs to the LDB17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM6_YERPS
Sequence: MNSPDIALIKTYLLTLQDNICAALAQADGHAEFTEECWVREEGGGGRSRVLVNGAVFEQAGVNFSHVSGAMLPASATAHRPELAGRSFQALGVSLVIHPLNPYLPTSHANVRFFIAEKPGEDAVWWFGGGFDLTPYYGFEEDAIHWHQVAHSLCQPFGEQIYPRYKKWCDDYFYIKHRQEARGIGGLFFDDLNSPDFMTCFNFTQAVGDGFLAAYMPIVARRKALGWGDRERQFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSLPPLVRWEYNYQPEADSAEAALYRDFLPVKDWLAIKGETH
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_SYNPW
Sequence: MANSFSPTEIFDVIVVGGGHAGCEAAITSARLGLNTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGVIGRLADATAIQKRILNASRGPAVWALRAQTDKRQYSRQMLQLLQHTPNLALREAMVTGLEIDGDPAGGGEHWDPSQGPAARITGVRTYFGSLYGAKAVVLTAGTFLGGRIWVGHQSMAAGRAGEQAAEGLTEALQQLGFHTDRLKTGTPARVDRRSIALDQLEEQPSDAADRFFSFDPAAWSSGEQMSCHITRTTAATHQLIKDNLHLTAIYGGVIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPEGRDTPEIYVQGFSTGLPEPIQLQLLRSLPGLEQAVMLRPAYSVDYDYLPATQLLPSLETKRVQGLFSAGQLNGTTGYEEAAAQGLVAGLNAARRIRAEEAVHFPREGSYIGTMIDDLVSKDLREPYRVLTSRSEYRLVLRGDNADRRLTPLGRELGLIDDRRWRLFEDKLQAMEAEKQRLEQQRLKVSDPAAPAVEQETGAPIKGSITLADLLRRPGMHAADLVRHGLADAGLPLPVREGAEIDIKYSGYLARQQQQIDQVKRQGRRKLPETIDYASISTLSREAREKLTAVRPLTLGQASQIPGVSQADLTSLLMWLELQQRRSQPSASHLAPTGQAR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_CYTH3
Sequence: MFPEYDVIVVGAGHAGCEAAAAAANMGSKVLLATMNMQTIAQMSCNPAMGGVAKGQIVREIDALGGLSGIVSDKSMIQFRMLNRSKGPAMWSPRSQNDRHMFAWEWRMQLEALPNVDFWQEMISGLIVKNGKVCGVRTGLGIEIPCKSVVLTNGTFLNGIIHIGEKKLGGGRTGEKAATGITEQLVELGFESGRMKTGTPPRVDGRSLDYSVMQEQEGDENPSKFSYSKQTTSLTKQRSCHITYTNQAVHDTLKEGFDRSPMFTGRIKGLGPRYCPSVEDKINRFAEKERHQIFVEPEGWNTVEVYVNGFSTSLPEDVQYKAIRKIAGFENAKMFRPGYAIEYDFFPPTQLQLSLETRLVKNLFFAGQINGTTGYEEAACQGLMAGINAHKAAKDHEALILKRSEAYIGVLIDDLVNKGTEEPYRMFTSRAEYRILLRQDNADLRLTPIGYEIGLATEERYQDMLLKKHNSEKLVEEIKNTKIKPETANEILEENGSAPIKEKVVLYNLLKRPNMEVSLFAEKVEEIKTLIEPYTQEEIEQAMIEVKYRDYIDKEEQMALKMTQLENMALNPDFDYKKIQALSLEAREKLSKLKPATLGQASRISGVNPADISILMIYMGR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TT30A_BOVIN
Sequence: MAGLGGEPIPDGEFTAVVYRLIRDARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLRQLHPELEQYRLYQAQALYKACLYPEATRVSFLLLDNPTYHNRVLRLQAAIKYSEGDLPGARSLVEQLLSEGGEDSGGENELDGQVNLGCLLYKEGHYEAACSKFSAALQASGYRPDLSYNLALAYFSSRQYASALKHIVEIIEHGIRQHPELGVGMTTEGIDVRSVGNTLVLHQTALVEAFNLKAAIEYQLRNYEAAQETLTDMPPRAEEELDPVTLHNQALMNMDARPTEGFEKLQFLLQQIPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLTYKFLTPYLYDFLDAMITCQTAPEEAFVKLDGLAGMLTEQLRRLTKQVQEARHNKDDEAIKKAENEYDDTLEKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNILKVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKIYHFCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKHMIVLRDSVIQECVQFLEHCELYGRNIPAVIEQPLEEERMHTGKNTVTYESRELKALIYEIIDWNM
What is the function of this protein?
Required for polyglutamylation of axonemal tubulin.  Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
What are the official names of this protein?
Tetratricopeptide repeat protein 30A, TPR repeat protein 30A.
What is the protein family that this protein belongs to?
Belongs to the TTC30/dfy-1/fleer family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: RPOC_BORGP
Sequence: MKEIKDFEKIKIKIASPDQIRNWSYGEVKKSETINYRTLRPEKDGLFCERIFGTTKEWECYCGKFKSIRYKGIICDRCNVEVTHFKVRRERMGHIELAAPVAHIWYYKYIPSRIGLLLDITASSLNSILYYEKYVVIEPGDTDLKKMQLLNEDEYIEARERYGMSFNASMGAEAIKTLLENLDLDELSSKLRIQMIDKDDKTDKKLLRRLEIIENFKVSGNKPEWMIMEVLPVIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLRKLLLLNAPEIIVRNEKRMLQESVDSLFDNSHKRKVVKGSSSRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPAKMALELFKPFVIRRLIESEAVFNIKRAKNLIEQEVDEVWQILDFVIKEHPILLNRAPTLHRLGIQAFEPVLVEGKAIKLHPLVCHAYNADFDGDQMAVHVPLTPSAQAESWALMLSTNNLLNPANGHPIVFPSQDIVLGLYYLTMEKKNIVGEGKKFLNFSNVILAINNRSLDYNASIYVKIDGEYKKTTAGRVIFNEALPKGIEFVNKTLSDLELQILISKVYVVHGSSTVIEMLDIIKELGFKYATKFGCTISMSDIIVPDEKKTYIDRANKEIAKIQNDYAKGVITGEERYNNVVSVWLKTNEELTNKMMEILKKDRDGFNVIYMMADSGARGSRNQIRQLAGMRGLMAKTSGDIIELPIISNFKEGLSVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVRIEDCGTINGIKVETVKNGEEILESLKEKAVGSYSIERIKNPITGEIVLDANEEISEAKIELLEKIGIEKLVIRSVLTCEAEHGVCQKCYGRDFSKNKPVNIGEAVGIIAAQSIGQPGTQLTMRTFHIGGVAQAGSEDDKISLKNAFILNSIEGFNVNVDNGILFTRKGTLKIINVFYEEKIKNIKEIKVLDSQRVIKGIPLFVNKKGVEILSSYIGYAKLRDDKFLIVSEEQEVALKAGTKLEIGVGDYVESGKVIGTFDPFAEPIIAEVKGKIKFKDIILGTTLKEEINTETGNVEKRITDNVFESLDPRIFIIDSSGMEVASYVLPGDAYLQVEDGQNINIGDVIAKLSKGSEKTQDITGGLPRVNDLFETRIPKNLTEMAKVSGIVQFKSIQKGKRLINILDEYGVEHKHYIPAGKHLLVRDGDVVKAGDMLCDGRINPHDVLEILGGISLQEFLLAEIQDVYRKQGVSINDKHIGVIIKQMMKKVKIVAVGDTNFVYGQKVDKHTFYEQNRKVIEQGGEPAIASPILIGVTKTSLNIDSFISAASFQETTKVLTDASIAGKIDDLRGLKENVVIGHLIPTGTGMGLYKKIKVSENIDAKV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RS12_POLNS
Sequence: MPTINQLIRKPRARLTVKSKSPAMQNSPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQARSKYGAKRAKKAA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: THYX_MYCBT
Sequence: MAETAPLRVQLIAKTDFLAPPDVPWTTDADGGPALVEFAGRACYQSWSKPNPKTATNAGYLRHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEKDSRVVVPPGMEDDADLRHILTEAADAARATYSELLAKLEAKFADQPNAILRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRQLAAVAPAVFADFEVTTLADGTEVATSPLATEA
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: URED_BEII9
Sequence: MTMSFAANRARGEIRVRYEKHGGITRPLRLFETGGLRLRHPRAFQGCVGMIVNSAGGIAGGDHLRLAIEAEEQSELVIATPAAEKIYRARDKAAMLDLSLVLAPETKLAFLPQETILFDGAALSRRLDVTMANDASLLLVETLVLGRLAHGESAISCDFRDSWRIRRGGRLVFAEESRIEGPLNRTFDQPSLGHGRRAMAFLLAVAPDAEARLESLRARLAPFEPACPHGVSAWNGMLVARLMAASPEVLRCALLAGLGLWRDDIARLWL
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.