PharMolix/UniProtQA huggingface dataset:
Protein: USPB_KLEP3
Sequence: MISTIALFWALCVVCVVNMARYFSSLRALLVVLRGCDPLLYQYVDGGGFFTSHGQPSKQMRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TAL_BACCN
Sequence: MKFFIDTANINEIKEANELGILAGVTTNPSLVAKEGVDFHERIREICGVVEGPVSAEVISLEADKMIEEGKELAKIAPNVVVKVPMTKEGLKAVKAFSDLGIRTNVTLVFSAVQALLAARAGATYVSPFLGRLDDIGHNGMDLIRQVAEIFAIHDIETEIIAASVRHSVHVTEAALNGAHIATIPANVIGALVKHPLTDQGIEKFLADWEKTQEK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_SALDC
Sequence: MSEPTSRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKNGPEEIDATADDYERVIAWCHEHHYLDDERFVMRFIASRSRKGYGPARIRQELNQKGISRESTEKAMRECEIDWSEMAREQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_ECOBW
Sequence: MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEFSVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLRSKKDRF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: PETL_CHAGL
Sequence: MISILTYFGILFGILTITVIIFVALNKIQLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: BP46_BPMU
Sequence: MTDLAIIWTNGRGDIAQDGIDMLTDDSLTTDVTISLFTDRRALDSDTLPDGSDDRRGWWGDSYRDRPIGSRLWLLSREKATPDTLERARGYAEEALEWLKTAGRVSAINVRAEQLHQGWLYLYIALTLPDGSVIPYEFKAAFNGV
What is the function of this protein?
Component of the baseplate.  Probable connector between the central and peripheral parts of the baseplate.  Probably involved in tail assembly.
What are the official names of this protein?
Baseplate protein gp46, Gene product 46, gp46, Gene product V, gpV.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=Baseplate protein.
Protein: HSLR_ECOL6
Sequence: MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSKPSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMALARKLNALTMPHPDRRPDKKERRDLLRFKHGDSE
What is the function of this protein?
Involved in the recycling of free 50S ribosomal subunits that still carry a nascent chain.  Binds RNA more specifically than DNA.  Binds with very high affinity to the free 50S ribosomal subunit.  Does not bind it when it is part of the 70S ribosome (By similarity).
What are the official names of this protein?
Heat shock protein 15, HSP15.
What is the protein family that this protein belongs to?
Belongs to the HSP15 family.
Protein: ACP_BRUAB
Sequence: MSDTAERVKKIVVEHLGVDADKVTEGASFIDDLGADSLDTVELVMAFEEEFGVEIPDDAAETILTVGDAVKFIDKASA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_MYCSK
Sequence: MRQILIAVGLALAVSILLTPVLIRLFTRQGFGHEIREDGPPTHHKKRGTPSMGGVAILAGIWVSYLGTHLVGLALDGEGPSASGLLVLGLATALGIVGFIDDLIKIRRARNLGLNKTAKTVGILAAALLFGVLALQFGNADGLTPGSPELSYVREIATVTLAPMIFVLFCVVLVSAWSNAVNFTDGLDGLAAGAMAMVCAAYVLITFWQYRNACATSPGLGCYNVRDPLDLALVAAAAAGACIGFLWWNAAPAKIFMGDTGSLALGGIIAGLSVTSRTEILAVVLGALFVAEVTSVVVQILAFRTTGRRVFRMAPFHHHFELVGWAETTVIIRFWLLTAIACGLGVALFYGEWLTAVGA
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y006_HIS1I
Sequence: MLTVKIINGDGAIDKHLTLNEKEAFKKTI
What are the official names of this protein?
Uncharacterized protein ORF6.
Protein: DNLJ_DINSH
Sequence: MSKDGPFRFGARGLWTSGQALLFLDPLGVWMGTPMNDTYVAVEALSEAAARKELARLSELLARANAEYHRDDAPSLSDADYDALKQRNAAIEARFPDLKRGDSPSDQVGAAPSDTFSKVTHAVRMLSLANAFSDEDIRDFDTRIRRFLGLAEDAPLAYTAEPKIDGLSLSLRYEHGTLVQAATRGDGAVGENVTANARTIDDIPHRLDGAPEVLEVRGEVYMSHADFAELNARQAETGGKTFANPRNAAAGSLRQLDAEITRARPLKFFAYAWGEISAPLAETQTETLARFREFGFTINPLTVRCETPEDMLAQYRAIEAQRATLGYDIDGVVYKLDDLDLQRRLGFRSTTPRWAIAHKFPAELAWTRLEAIDIQVGRTGALSPVARLAPVTVGGVVVSNATLHNEDYIQGRDNTGAPIRWGTDIRVGDWVQVYRAGDVIPKIRDVDLSRRPEGAAPFDFPTTCPECGSDAPREPGDAVRRCSGGLICPAQAVEKLKHFVSRGALDIDGLGAKQVEQFYRDGWIAEPADIFTLRARFGQGLQQLKNREGWGDKSAENLFRAIDTARTAPFAKVLFGLGIRHIGESASSLLANHYLTMEALLAAVDAAVDETSDAWADLLNIDGVGEVMARALVTTLTQEAERASVNRLLAQIDPAPATPPQVGDSPVAGKTLVFTGTLETMSRAEAKATAEALGAKVAGSVSAKTDLLIAGPGAGSKATKAEALGIEVIDEDAWRVLAGLA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AN_HCMVM
Sequence: MWGVSSLDYDDDEELTRLLAVWDDEPLSLFLMNTFLLHQEGFRNLPFTVLRLSYAYRIFAKMLRAHGTPVAEDFMTRVAALARDEGLRDILGQRHAAEASRAEIAEALERVAERCDDRHGGSDDYVWLSRLLDLAPNYRQVELFQLLEKESRGQSRNSVWHLLRMDTVSATKFYEAFVSGCLPGAAAADGSGGGGSHYTGSRAGVSPGIQFGIKHEGLVKTLVECYVMHGREPVRDGLGLLIDPTSGLLGASMDLCFGVLKQGSGRTLLVEPCARVYEIKCRYKYLRKKEDPFVQNVLRRHDAAAVASLLQSHPVPGVEFRGERETPSAREFLLSHDAALFRATLKRARPLKPPEPLREYLADLLYLNKAECSEVIVFDAKHLNDDNSDGDATITINASLGLAAGDAAGGGADHHLRGSPGDSPPPIPFEDENTPELLGRLNVYEVARFSLPAFVNPRHQYYFQMLIQQYVLSQYYIKKHPDPERIDFRDLPTVYLVSAIFREREESELGCELLAGGRVFHCDHIPLLLIVTPVVFDPQFTRHAVSTVLDRWSRDLSRKTNLPIWVPNSANEYVVSSVPRPVSP
What is the function of this protein?
Plays a role in processing non linear or branched viral DNA intermediates in order to promote the production of mature packaged unit-length linear progeny viral DNA molecules.  Exhibits endonuclease and exonuclease activities and accepts both double-stranded and single-stranded DNA as substrate.  Exonuclease digestion of DNA is in the 5'-> 3' direction and the products are 5'-monophosphate nucleosides.  Additionally, forms a recombinase with the major DNA-binding protein, which displays strand exchange activity.
What are the official names of this protein?
Alkaline nuclease.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae alkaline nuclease family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: CN37_RAT
Sequence: MSTSFARKSHTFLPKIFFRKMSSSGAKDKPELQFPFLQDEDTVATLHECKTLFILRGLPGSGKSTLARLIVEKYHNGTKMVSADAYKIIPGSRADFSEEYKRLDEDLAGYCRRDIRVLVLDDTNHERERLDQLFEMADQYQYQVVLVEPKTAWRLDCAQLKEKNQWQLSLDDLKKLKPGLEKDFLPLYFGWFLTKKSSETLRKAGQVFLEELGNHKAFKKELRHFISGDEPKEKLDLVSYFGKRPPGVLHCTTKFCDYGKATGAEEYAQQDVVRRSYGKAFKLSISALFVTPKTAGAQVVLNEQELQLWPSDLDKPSSSESLPPGSRAHVTLGCAADVQPVQTGLDLLEILQQVKGGSQGEEVGELPRGKLYSLGKGRWMLSLAKKMEVKAIFTGYYGKGKPVPVHGSRKGGAMQICTII
What is the function of this protein?
Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates (By similarity).  May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).
What are the official names of this protein?
2',3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNPase.
What is the protein family that this protein belongs to?
Belongs to the 2H phosphoesterase superfamily. CNPase family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Melanosome. Note=Firmly bound to membrane structures of brain white matter.
Protein: ATPG_GEOKA
Sequence: MASLRDIKTRINATKKTSQITKAMEMVSTSKLNRAEQNAKSFVPYMEKIQEVVANVALGAGGASHPMLVSRPVKKTGYLVITSDRGLAGAYNSNVLRLVYQTIQKRHASPDEYAIIVIGRVGLSFFRKRNMPVILDITRLPDQPSFADIKEIARKTVGLFADGTFDELYMYYNHYVSAIQQEVTERKLLPLTDLAENKQRTVYEFEPSQEEILDVLLPQYAESLIYGALLDAKASEHAARMTAMKNATDNANELIRTLTLSYNRARQAAITQEITEIVAGANALQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HSP90_CANAL
Sequence: MADAKVETHEFTAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPSQLESEPELFIRIIPQKDQKVLEIRDSGIGMTKADLVNNLGTIAKSGTKSFMEALSAGADVSMIGQFGVGFYSLFLVADHVQVISKHNDDEQYVWESNAGGKFTVTLDETNERLGRGTMLRLFLKEDQLEYLEEKRIKEVVKKHSEFVAYPIQLVVTKEVEKEVPETEEEDKAAEEDDKKPKLEEVKDEEDEKKEKKTKTVKEEVTETEELNKTKPLWTRNPSDITQDEYNAFYKSISNDWEDPLAVKHFSVEGQLEFRAILFVPKRAPFDAFESKKKKNNIKLYVRRVFITDDAEELIPEWLSFIKGVVDSEDLPLNLSREMLQQNKILKVIRKNIVKKMIETFNEISEDQEQFNQFYTAFSKNIKLGIHEDAQNRQSLAKLLRFYSTKSSEEMTSLSDYVTRMPEHQKNIYYITGESIKAVEKSPFLDALKAKNFEVLFMVDPIDEYAMTQLKEFEDKKLVDITKDFELEESDEEKAAREKEIKEYEPLTKALKDILGDQVEKVVVSYKLVDAPAAIRTGQFGWSANMERIMKAQALRDTTMSSYMSSKKTFEISPSSPIIKELKKKVETDGAEDKTVKDLTTLLFDTALLTSGFTLDEPSNFAHRINRLIALGLNIDDDSEETAVEPEATTTASTDEPAGESAMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 90 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_CLOBA
Sequence: MVRKKSSNTLAENRKARHEYFIEETIEAGIALVGTEVKSIRNGRANLKESYADIRNGEIFILSMHISPYEQGNIFNVEPLREKKLLLHKSEIHRLAGLVSRDGYTLIPLTLYLKAGKVKVALGICKGKKDYDKRDSMLEKAHNREMQRALKERSRY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: REX_STRPS
Sequence: MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIGIDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLHYRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSVKSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSCP_HYPVG
Sequence: MQITKTLVATLFAASTAFAAPTPADKSMMAAVPEWTITNLKRVCNAGNTSCTWTFGVDTHLATATSCTYVVKANANASQASGGPVTCGPYTITSSWSGQFGPNNGFTTFAVTDFSKKLIVWPAYTDVQVQAGKVVSPNQSYAPANLP
What is the function of this protein?
Stimulates salicylic acid signaling in host plant roots.
What are the official names of this protein?
Effector TSP1, Small secreted cysteine-rich protein, SSCP.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBL_CONAR
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL3_HELMI
Sequence: MAKKGLLGRKIGMTQVFADNGVAVPVTVVQAGPCVVVQKKTVEKDGYEAVQIGFGDVREKLLNKPKRGHLKNAGVRLVRVLREIKVDSMDEYKVGQELKADVFSAGEYVDVVGTSKGKGFAGGIKRHNFKRGPMKHGSKYHRRPGSAGAKGPARIFKGRKMPGRMGNERVTVQKLQVVRVDAERNLLLIKGAVPGPKRGLLLIKSSIKAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: DRTS_LEIMA
Sequence: MSRAAARFKIPMPETKADFAFPSLRAFSIVVALDMQHGIGDGESIPWRVPEDMTFFKNQTTLLRNKKPPTEKKRNAVVMGRKTWESVPVKFRPLKGRLNIVLSSKATVEELLAPLPEGQRAAAAQDVVVVNGGLAEALRLLARPLYCSSIETAYCVGGAQVYADAMLSPCIEKLQEVYLTRIYATAPACTRFFPFPPENAATAWDLASSQGRRKSEAEGLEFEICKYVPRNHEERQYLELIDRIMKTGIVKEDRTGVGTISLFGAQMRFSLRDNRLPLLTTKRVFWRGVCEELLWFLRGETSAQLLADKDIHIWDGNGSREFLDSRGLTENKEMDLGPVYGFQWRHFGADYKGFEANYDGEGVDQIKLIVETIKTNPNDRRLLVTAWNPCALQKMALPPCHLLAQFYVNTDTSELSCMLYQRSCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYRNHVDALKAQLERVPHAFPTLIFKEERQYLEDYELTDMEVIDYVPHPAIKMEMAV
What is the function of this protein?
Bifunctional enzyme.  Involved in de novo dTMP biosynthesis.  Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
What are the official names of this protein?
Bifunctional dihydrofolate reductase-thymidylate synthase, DHFR-TS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidylate synthase family.
Protein: MLRV_MOUSE
Sequence: MAPKKAKKRIEGGSSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGSLKADYVREMLTTQAERFSKEEIDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD
What is the function of this protein?
Contractile protein that plays a role in heart development and function (PubMed:10409661).  Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force.  These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity) (PubMed:22426213, PubMed:16908724, PubMed:10409661).  During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (PubMed:9422794).
What are the official names of this protein?
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, MLC-2, MLC-2v, Myosin light chain 2, slow skeletal/ventricular muscle isoform, MLC-2s/v.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, A band.
Protein: SCNA_THITI
Sequence: MSDSHHKPVWDRTHHAKMATGIGDPQCFKGMAGKSKFNVGDRVRIKDLPDLFYTRTMTYTRGATGTIVRLVYESPAAEDEAFGNEENVEWFYSIVFAQKDLWPEYSDTFANDTLETEIPERYLEKA
What is the function of this protein?
Involved in the degradation of thiocyanate.
What are the official names of this protein?
Thiocyanate hydrolase subunit alpha.
Protein: TRM10_CANGA
Sequence: MSDTSDLVDGKWQRLPPVPEGMSKSQWKKQWRRQMYEAKKEEYAEVRKEKRKRAKENRRKKIQEYIDRGEEVPAELKREPRVNRDQVASGINIILDCAFDDLMNDKEIVSTSNQITRAYSANRRASQYANITVTSFNKRLKERFDKALDDCNYPQWQNFKFVSDEKLITEGDKSKMVYLTADTEEQLDTLEPGMTYIVGGIVDKNRHKLLCYNKAKELGIPTRRLPIGEYIKIEGRKVLTTTHVIQLMLKYCESRDWKESFESVIPSRKLDPVKEKEQQQQQQQQQQ
What is the function of this protein?
S-adenosyl-L-methionine-dependent guanine N(1)-methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in cytoplasmic tRNA.
What are the official names of this protein?
tRNA (guanine(9)-N1)-methyltransferase, tRNA methyltransferase 10, tRNA(m1G9)-methyltransferase, tRNA(m1G9)MTase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: EX7L_NAUPA
Sequence: MTPISVTQLNNQIKSIVESHFEIVLVEGEISKVVYHSSGHLYFTLKDENSSINCAMWKSNLTRMKFRLKEGEKVYVYGALSVYVPRGEYKIIAQSIEPSGVGALQKAFEQLKEELSKLGYFDEARKKSIPRFPRRIAIVTSATGAALQDMLRVAGKRWQLTEIYLFNALVQGDGAAEDIAMKIKLADEFVFEDGSGFDLIIIGRGGGSKEDLWPFNERVVADAVYNASTPIISAVGHEIDYLISDFVADVRAATPSNAMEIALPDKNEILLMLDEMKNAFVYKISHLIQKKERELIHIRELLNASSPVKKLDMKLQECELLLKRFNHSYINQIQKKEKELNELKNILFSLSPVIKINSFEKEIELLKSTFKNKTAQIISSKEKELINLKSAYETLNPKKREKKGFAEITKNGKRIDLKELKIGDIFDVSNADVLIKSKALEKIEN
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCN2_HUMAN
Sequence: MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEKQSRLCMVRPCEADLEENIKKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGRCCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIFESLYYRKMYGDMA
What is the function of this protein?
Major connective tissue mitoattractant secreted by vascular endothelial cells.  Promotes proliferation and differentiation of chondrocytes.  Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells.  Enhances fibroblast growth factor-induced DNA synthesis.
What are the official names of this protein?
CCN family member 2, Cellular communication network factor 2, Connective tissue growth factor, Hypertrophic chondrocyte-specific protein 24, Insulin-like growth factor-binding protein 8, IBP-8, IGF-binding protein 8, IGFBP-8.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Secreted.
Protein: NSP4_ROTRA
Sequence: MDKLTDLNYTLSVITLMNSTLHAILEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALKTSRCSYKVIKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVIREMRRQLEMIDKLTTREIEQVELLRRIYDRLTVRKTDEIDMSKEINQKNIRTLDEWENGKNPYEPSEVTASL
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.