PharMolix/UniProtQA huggingface dataset:
Protein: SSPB_STAAS
Sequence: MNSSYKSRVFNIISIIMVSMLILSLGAFANNNKAKADSHSKQLEINVKSDKVPQKVKDLAQQQFAGYAKALDKQSNAKTGKYELGEAFKIYKFNGEEDNSYYYPVIKDGKIVYTLTLSPKNKDDLNKSKEDMNYSVKISNFIAKDLDQIKDKNSNITVLTDEKGFYFEEDGKVRLVKATPLPGNVKEKESAKTVSSKLKQELKNTVTPTKVEENEAIQEDQVQYENTLKNFKIREQQFDNSWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSEQDLPNCSTFPNQMIEYGKSQGRDIHYQEGVPSYEQVDQLTKDNVGIMILAQSVSQNPNDPHLGHALAVVGNAKINDQEKLIYWNPWDTELSIQDADSSLLHLSFNRDYNWYGSMIGY
What is the function of this protein?
Cysteine protease that plays an important role in the inhibition of host innate immune response.  Degrades host elastin, fibrogen, fibronectin and kininogen.  Blocks phagocytosis of opsonised S. aureus by neutrophils and monocytes by inducing their death in a proteolytic activity-dependent manner.  Decreases surface expression of the 'don't eat me' signal CD31 on neutrophils.  Cleaves host galectin-3/LGALS3, thereby inhibiting the neutrophil-activating ability of the lectin.
What are the official names of this protein?
Staphopain B, Staphylococcal cysteine proteinase B, Staphylopain B.
What is the protein family that this protein belongs to?
Belongs to the peptidase C47 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL22_STRP3
Sequence: MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTPNKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINKRTTHVTVVVSEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MRAZ_NITMU
Sequence: MFRGGTPVSLDNKGRLAVPARYRETLISLCAGHLIVTADPSKCLLIYPQPVWEPIEQKLNSLSSFNPQTRSLQRLLVGNACDVEMDGVGRILVPPSLRAFAGLNKEVVLVGQGAKFELWDSEKWNLQMESALAFRDGIPQELEGFSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: DCUP_SINMW
Sequence: MSGTHRKVLEVLNGRSLTPPPIWLMRQAGRYLPEYRATRIKAGSFLDLCYTPELAVEVTLQPIRRYGFDAAILFSDILVVPDALNRNVRFEEGQGPRMDPIDEDGIAQLSQTGVIEHLAPVFETVSRLRGELAAEITLLGFCGAPWTVATYMIAGRGTPDQAPARLFAYRHPKAFERLLALLADISADYLVEQIDRGADAVQIFDSWAGVLGEEEFQRYAVEPVRRIIASVRSRRPSAKIIAFAKGAGILLKNYRQATGADAIGLDWSVPLSFAAELQKDGPVQGNLDPVRVVAGGAALEHGIDRILDVLGQGPLIFNLGHGITPDADPEHVAALVSRVRGRR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOD1_VIBVY
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDVVQVCDVRNMYGFTGTYKGRKVSVMGHGMGIPSCSIYATELIKDYGVKKIIRVGSCGAVSTDIKVRDVVIGMGACTDSKVNRIRFKGHDFAAIADYKMVKAAEEAAKARGIDVKVGNLFSAELFYTPDPEMFDVMDKYGIVGVEMEAAGIYGVAAEYGAKALTICTVSDHIKTGEQTTSEERQNTFNDMMIVALDSVLLGDAE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type 1, PNP 1.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: MIS4_SCHPO
Sequence: MLFEMTPETFKKVNSSNRIIKGLQYTPLASSIPLENGLQNVLYPSSKFQNEPLQLNSEESSIMQRYVDMLNPGATFVNDSETFNFYKNALSAMITEPAMPAMRVNASPVLDQKVCNSDSLSELNDFTKSLIQPSMLMCEPKEKPDASSINTNRSSSDNGFLTPSSSPRSPSCSRVFNAVQLCSPKKSKDDITTPKKRLMEDTYSPRESPSKIQRLQDVLLKQLQDTRLLISQVIEAENSEDFSSNSLFIKREDDDGKHISSHAIEKLYMALTKLSRLGACDKLLEEGSIILVKQILEKELKELPVACYSIINLHDSLTQFPNLDFILKTTALVLFIIFLVPSFKKLQNEESILHLLNILHSIFEYTVPEAIDNIVQSKTSDARTSEIQHLSVLLQKVANVLNILSKVAHEIPLSEAVVIRIVYLFPKVSTLDNSFKTKLPNCNSSSFDFLKAPLFQTLQYLFRLYPYQRDFIIEESLTNFSHLPTARSVSRTYRLSNGKSIQYYSTLFVRLIQSCSIQNLFDSEIVQSESKSTEALHSGNLTEHLKTVESILSKSRHEEYRIANHIVAYLLSRSLKQNKTESDNSFAILTKILLEDLLNMLSLPEWCGTETIIRQFAMNLVMTVTNDKQAVSSKNAALDLISLIVNKVLALFDLSLFEKHNIPAPTNFNDIISFIPSITRLNELSQVSFNHFYFLCKGDISLENILPYNYNKWFSFLLQLRKVCNDSEALKIIDNCIDKNMQKSQEGFQGPSPFKADENDEDIFIISLYHSSLFLNLKFFVSLIIGFLDSPQASLRTKCLRIINQMKTIPSILRTHPEVLAQIISKSNDQSAIVRDTVLDLLGTYIMAYRETIPQIYGCIISGISDPSTIVRKRAIKQLCEVYEATEDLNIRVDIASKLLTRSNDEEETISELSLEVLEKLWFSPASNELDCQKGYEQLTFLEKQKLRVQYFPILKLCAEPSTERHVLLVTSLKTMLTSKEEINLSTLHTQIRLLLSCLFNQLIEVVTEDQVDESTKGILYEIMSTLFVFSRAFPFLFDLSYLHLLKPYLRSASTIEEQRFLYYVVAIFRQVLPFQKEISESFLRSLESVLLQRLTKAGTATLMEIVPCLCSLFTRLNDYERLKKIVVSCLKSLEEARHSENNFQKMVRLIDLIGLFSRYGDLNRINDDWKHSLDFISPECDDAYVILLGYFQKLLKDAKGQLRIHIIDNMSRICLRETSLFISPLMLSTLDMIIAENNVNEVSVLFKSFLELLAADEDLIFEADQKLSLKGKQNVQSNKSVDRDMLKGTKDKQWIEGVSASLMQHFLPCILDSCFSKNLRYSMLGIEILKCIIHQGLVNPRMCFSTIIALESNAIKETREVAILLHTELHRRHESLIDGLYAQSADLIFSLQKTEEYQTFKLGEFSPFQSAYTIVSADKSSKSRKKLIMQILKPLKLDGIDLPSFTEEKVSFVSFCCVCLAGIPYVSIEEPLMIISTVDSVLATIGPTITGWMKKLDHERFKILAGINLCNLIYLKRYIKYAFSISDSSRPIREKKPLTLLNRGYVDLITSDAKPDIVSKLVIKLFEEENILSGEDQVEGEQLTVV
What is the function of this protein?
Plays a structural role in chromatin.  Chromatid cohesion molecule required for equal sister chromatid separation in anaphase.  May form a stable link between chromatids in S phase that is split rather than removed in anaphase.  Also required for spindle-kinetochore interaction in early mitosis and inhibit sister chromatid separation until the cleavage of Rad21 in anaphase.
What are the official names of this protein?
Sister chromatid cohesion protein mis4, SCC2 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC2/Nipped-B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromosomes in a punctate fashion throughout the cell cycle.
Protein: VA727_ARATH
Sequence: MSQKGLIYSFVAKGTVVLAEHTPYSGNFSTIAVQCLQKLPTNSSKYTYSCDGHTFNFLVDNGFVFLVVADESTGRSVPFVFLERVKEDFKKRYEASIKNDERHPLADEDEDDDLFGDRFSVAYNLDREFGPILKEHMQYCMSHPEEMSKLSKLKAQITEVKGIMMDNIEKVLDRGEKIELLVDKTENLQFQADSFQRQGRQLRRKMWLQSLQMKLMVAGAVFSFILIVWVVACGGFKCSS
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
What are the official names of this protein?
Vesicle-associated membrane protein 727, AtVAMP727.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Early endosome membrane; Single-pass type IV membrane protein. Endosome membrane; Single-pass type IV membrane protein. Note=Co-localizes with VPS3.
Protein: Y1475_SYNWW
Sequence: MNRELGLWGEELAAQYLRKKGYKILERNFHTRYGELDLVCEKDDNIVFVEVKTRRSTRFGSPEEAVTPRKIGNLKKAAILYLKSTPRFFPEISFDVVSILVEDGKSKINHIINAF
What are the official names of this protein?
UPF0102 protein Swol_1475.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: KLHL7_RAT
Sequence: MATSGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKSTADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex.  The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins.  Probably mediates 'Lys-48'-linked ubiquitination (By similarity).
What are the official names of this protein?
Kelch-like protein 7.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Colocalizes with CUL3 in punctate structures at the perinuclear region of the cytoplasm.
Protein: KDSB_DELAS
Sequence: MPTAPFTVLIPARLASSRLPGKPLADIAGLPMVVRVAQRAGLSGATRCVVAADDESIVAACAAHGVAAVLTRSDHASGSDRLAEACELLGLDGDDIVVNVQGDEPLIAPDLIDAVAALLPQQPSASMGTAAHAIDSLADFTNPNVVKVVCDAQGMAHYFSRAPIPFAREHAGQAWWEAASAAASAAPGHPGFAPLRHIGIYSYRAGFLRSFPQLSPAPTEVLEALEQLRALWHGHRIAVHLTPHAPGPGVDTPEDLERVRARLSA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHSO_RAT
Sequence: MAAPAKGENLSLVVHGPGDIRLENYPIPELGPNDVLLKMHSVGICGSDVHYWEHGRIGDFVVKKPMVLGHEAAGTVTKVGPMVKHLKPGDRVAIEPGVPREIDEFCKIGRYNLTPSIFFCATPPDDGNLCRFYKHSADFCYKLPDSVTFEEGALIEPLSVGIYACRRGSVSLGNKVLVCGAGPIGIVTLLVAKAMGASQVVVIDLSASRLAKAKEVGADFTIQVAKETPHDIAKKVESVLGSKPEVTIECTGAESSVQTGIYATHSGGTLVVVGMGPEMINLPLVHAAVREVDIKGVFRYCNTWPMAVSMLASKTLNVKPLVTHRFPLEKAVEAFETAKKGLGLKVMIKCDPNDQNP
What is the function of this protein?
Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols (By similarity).  Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose (PubMed:6862079).  Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism.  May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility (By similarity).
What are the official names of this protein?
Sorbitol dehydrogenase, SDH, L-iditol 2-dehydrogenase, Polyol dehydrogenase, Xylitol dehydrogenase, XDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Peripheral membrane protein. Cell projection, cilium, flagellum. Note=Associated with mitochondria of the midpiece and near the plasma membrane in the principal piece of the flagellum. Also found in the epididymosome, secreted by the epididymal epithelium and that transfers proteins from the epididymal fluid to the sperm surface.
Protein: METK_MYCS5
Sequence: MKKLFTSESVGRGHPDKICDQISDAILDAYLTWDPHSKVAVETMVSGNNVFIAGEVKSKVTVDVIEIAKNVLRNIGYYSNNTSFITDIKSQSENIAMGVNLQDSDDLGAGDQGFMFGYATNETSQYMPLGITLCNKIVSRAGMLIKNQEFKDAKEDMKTQVTLDYSDPQNVKVDTIIFSCHHNEKYNETKFKNYIKTQILKPVLDEFNLELPERILINPTGKFVIGGPFSDTGLTGRKIIVDTYGGSARHGGGAFSGKDATKLDRSGAYMARWIAKNLVAANIADKIEVQIAYSIGVAKPVSVMVNTFGENKVPEDVVLDAILNNFELTPKGIIKSLNLNKPIYQKSSVYGHFGREDFQFTWESLDKVEAIREFVISKGFNI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_STAA3
Sequence: MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKKTGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKNNQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFWQVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPYNINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLTGKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4HL_SINFN
Sequence: MSLNVISDDRTPHQHGTWNVAGALAPKVETSNSAHHDADSHSVVYDARYAKRPENHLAAIVNLVATNLNGAISKEHRKFESGRRS
What are the official names of this protein?
Uncharacterized protein y4hL.
Protein: 3L22_OXYMI
Sequence: MKTLLLTLVVVTIVCLDLGYTRRCFITPDVRSERCPPGQEVCYTKTWCDGFCSSRGKRVDLGCAATCPTPKKKGIDIICCSKDNCNTFPKWP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 2, LNTX-2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLPS_BURA4
Sequence: MAIIPDKQDSTVLERKQQKLKPPSMYKVVLLNDDFTPMEFVVMVVQEYFKKDRETATQIMLKVHREGRGVCGVYTRDIASTKVEQVVTHARQAGHPLQCVMEEA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: NDHH_SOYBN
Sequence: MNISTTRKDFMIVNMGPHHPSMHGVLRLIVTLDGEDVIDCEPILGYLHRGMEKIAENRTIIQYLPYVTRWDYLATMFTEAITVNGPEQLGNIQVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYIFRERELIYDLFEAATGMRMMHNFFRIGGVATDLPYGWVDKCYDFCDYFLTRIVEYQKLITRNPIFLERVEGVGVVDIKEVINWGLSGPMLRASGIQWDLRKVDNYECYEEFDWEVQWQKEGDSLARYLVRIGEMMESIKIIQQALEGIPGGPYENLEIRCFDREKEPEWNEFEYRFISKKPSPTFELPKQELYVRIEAPKGELGIFLIGDQNGFPWRWKIRPPGFINLQILPQLVKRMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: NDHI_ZALME
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: S35B3_PONAB
Sequence: MDLTQQAKDIQNVTVEETNKNNSESIECSKITMDLKFNNSRKYISITVPSKTQTMSPHIKSIDDIVVLGMNLSKFNKLTQFFICVAGVFVFYLIYGYLQELIFSVEGFKSYGWYLTLVQFAFYSIFGLIELQPIQDKRRRIPGKTYMIIAFLTVGTMGLSNTSLGYLNYPTQVIFKCCKLIPVMLGGVFIQGKRYNVADVSAAICMSLGLIWFTLADSTIAPNFNLTGVVLISLALCADAVIGNVQEKAMKLHNASNSEMVLYSYSIGFVYILLGLTCTSGLGPAVTFCAKNPVRTYGYAFLFSLTGYFGISFVLALIKIFGALIAVTVTTGRKAMTIVLSFIFFAKPFTFQYVWSGLLVFLGIFLNVYSKNMDKIRLPSLYDLINKSVEARKSRTLAQTV
What is the function of this protein?
Mediates the transport of adenosine 3'-phospho 5'-phosphosulfate (PAPS), from cytosol into Golgi.  PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi.  Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon (By similarity).
What are the official names of this protein?
Adenosine 3'-phospho 5'-phosphosulfate transporter 2, PAPS transporter 2, Solute carrier family 35 member B3.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: HIS7_METS5
Sequence: MSRYVEKVRETKETKVQVKLELDGEGKVEIRTPVPFFDHMLHSMLFYMKVNATILGEDKQGYDDHHIVEDVGITLGQAIKDALGDRRGIKRFSSAVIPMDEALVLVAVDVSGRGYASTNLDLKREKIGDLSTENVAHFFWSLATNAGITLHVRKLDGVNEHHIVEAAFKGVGLALGEACSIQGEGIRSTKGSL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATOSA_CHICK
Sequence: MNAERNGSSTDTLDEYFEYEAEEFLVSLALLITEGRTPEHSIKGRTEGFHCPPAQSSQPPTTKHECSDKLAQCRQARRTRSEVMLLWKNNIPIMVEVMLLPDCCYSDEGPNTEGNDLNDPAIKQDALLLERWILEPVPRQSGDRFIEEKTLLLAVRSFVFFSQLSAWLSVSHGAVPRNILYRVSAADVDLQWTFSQTPTEHVFPVPNVSHNVALKVSVQSLPRQSNYPVLTCSIHTNLSYYEKQMKERKLHQHSESSTAELCGTSSPQRVCGKQAWTVIPEGLLNVKKTPEFTSSIRNLKLYPSTGLGSDFAASQSKIQCYNAAADSKTQSHETAVRTFKSLSLVDSRVSNGHCSHQSTGETNPLIGSLLQERQEVIARIAQHLIHCDPATSPVVAGRPFNMRETSTPTPKAYRSTYEDESLLRKGKETSPVPTVNLDNAIQEDGGEGKTRAIPEMPRLNPRAPVNHCGRPSAGEGNPLIDSLLQERRDVIARIAQHLIHCDPATSHVNGRPFKIHETSPVSSKIFRSTYEDENLLKKVKQPSSVSFAKSSFSLLEDSSKSKLKTPDTPISPRLDGESKASLKLQARRKLVLAKPSDAVQNAFHQTSNKTSHSFTNTHTSSSCVKENKSELLDKLEMMQSDYVQKDQITNRIKQCSNFSSVDEQICTNKLKERTVVSESNNTGTLNNLQIDKCRILEGTKKATVMQASDSLHKNELKCSDKDSKKPSIYEQNTQLISIENYLNKDHDNFKNKNRQDKTKAAHDENEEPVGLDFQSTSQKKPTEDGSMRCERLKNPDVQRAPSLKHTNTWRKHNFRSLDGTSTKAFHPRTGLPLLSSPVPQRKTHSGCFDLDSSLLQLKCLSARSPQQCINRESDPESHGKPFLSSSAPPVTSLSLLGNFEESVLNFRLDPLGIVEGFTAEVGASGVFCPTHMTLPVEVSFYSVSDDNAPSPYMGVITLESLGKRGYRVPPSGTIQVTLFNPNKTVVKMFVVIYDLREMPANHQTFLRQRTFSVPVRREIKRTVNKENSQQTEERLLRYLIHLRFQSSKSGKIYLHRDVRLLFSRKSMEVDSGAAYELKSYTESPTNPQFSPRC
What is the function of this protein?
Transcription regulator that syncronizes transcriptional and translational programs to promote macrophage invasion of tissues.
What are the official names of this protein?
Atos homolog protein A.
What is the protein family that this protein belongs to?
Belongs to the ATOS family.
Protein: IF4A2_CHICK
Sequence: MSGGSADYSRDHGGPEGMEPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIDLKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLSTNIQVVLLSATMPMDVLEVTKKFMREPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-II, eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: PCKG_TREPS
Sequence: MELHEIAHARAKAWIEEMVALCAPDTVYVCDGSKKEYDTIMQKMVDAGLATPLKKRKNCFLFRSQPSDVARVEARTFIASKREDDAGPTNHWTDPAELKKTMTGLYSQCMKGRTMYVIPFSMGPVGSPISKNGIEITDSEYVVCNMHIMTRVGTRVLEALGTDGEFVPCLHSVGKPLGPGVTDAGQWPCADMERKYISHFPEERLVWSFGSGYGGNALLGKKCFALRIASVLARDEGWLAEHMLILKITNPAGKTKYIGAAFPSACGKTNLAMMIPTLPGWKVETVGDDIAWMKFGKDGRLYAINPEAGFFGVAPGTSDFSNKNAMDSIKENAIFTNCGLTEDGDVWWEGIGYPAKGTIIDWHGVSRPAPTRDKSPKGEEIAHPNARFTAPARQCPAIASNWEDPEGVPIDAFLFGGRRPSTVPLVHQARDWNHGVFLGSIIGSEVTAAVISDQVGQIRRDPFAMLPFCGYHMADYFSHWIKLGSQARAENLPKIFCVNWFRKDAEGNFLWPGYGDNSRVLAWIFDRCDGVDNAVETAIGWMPKEGALNTEGLNVSTQAVKELLSVDIAGWKKEIKDIRENHYPKFGARLPQQLRDALEVLEARINGSEGAACTRDMC
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP).
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK, GTP-dependent phosphoenolpyruvate carboxykinase, GTP-PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VM3LC_MACLN
Sequence: IVSPPVCGNELLENGEECDCGSPANCRNPCCDAASCRLHSWVECESGECCDQCRFVTAGTECRATRSECDLAGQCTGQSADCPIDRFHRNGQPCLQNYGYCYNGKCPIMHHQCYYLFGANATVAQDACFEENKNGIGDFYCRKQSDRLIPCAPEDVKCGRLFCEILPNTRCKHAPGDNGMVDPGTKCEDKKVCFNRKCVDVNTVY
What is the function of this protein?
Inhibits platelet aggregation induced by thrombin and arachidonic acid with IC(50) of 40 and 50 nM respectively (in rabbit platetelet-rich plasma).  It also inhibits the adhesion of melanoma tumor cells on fibrinogen and fibronectin, by interfering with the function of alpha-V/beta-3 (ITGAV/ITGB3) and, to a lesser extent, with alpha-V/beta-6 (ITGAV/ITGB6) and alpha-5/beta-1 (ITGA5/ITGB1) integrins.
What are the official names of this protein?
Disintegrin-like leberagin-C.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y025_BORT9
Sequence: MSGHSKWSTIKRKKGALDAKRNKIFTKLIREISIAAKMGGGDIESNSRLRLAVNKARVSNMPKDNIEKAIKKGSGDDNIGSEYFELTYEAYAPHGVALIIKCLTDNKNRTASEVRSVLSKSGGSLGAPGSVSYMFHKKGLISYSLDKYPEDEIIELALEAGAEDIYSEGSQIEVITSAENFEAISSFLRTKFEEDIAEIALIPGNKLSLNKEQMDKVLALIEKLEDFDDVQEVVHNLEIIDEIN
What are the official names of this protein?
Probable transcriptional regulatory protein BT0025.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP1_ALOSE
Sequence: MARYRCCRSRSLSRSRCYRQRPRCRRRRRRSCRRPRASRCCRRRYRLRRRRY
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL23_SHEFN
Sequence: MIREERLLKVILGPHISEKSTVLAEKNNTVVFRVAIDATKAEIKAAVAKLFEVEVDSVRTLVNKGKTKRTGGRVGRRIDWKKAYVTLAAGAEIDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.