PharMolix/UniProtQA huggingface dataset:
Protein: ILKH_CAEEL
Sequence: MSLSTHYHAHKPNVPIIMEDVFGWVREGNAFQVRVWLDDHEHDLNVGDDHAFSLLHWAAKGGHVAIAEMLLSRGARVNSTNMGDDTSLHLAAAHGHRQIVVKLLSRKADVNATNEHGMTPLHYACFWGYEQIAEDLISCGAAVNVCNKKGMTPLDVCQPMCKNTILEIAQEHGQSPNDRVPFKDTTWKGTKSRTRDATLSRYTGVDVSSLNLITKIAESHSGELWRGKWQGNDIVARILNVQEVTARISRDFQTEFPALRIFAHPNICAVLAAANQPPNLVIISQYMPFGSLYNVLHEQSSVVIDHGQAVRFALDIARGMSYLHSLDPMLLRFYLSSKHVVVDEELTAKLSMADTKFSFQEVGKAYSPAWMSPEALSRAPEDLNIRAADMWSFAILLWELNTREVPFSDLPPMECGMKIALEGLRVHIPPGIARNMNRLMNICMNEDPGRRPNFDQIIPILERMIL
What is the function of this protein?
Probable pseudokinase that acts as an adapter protein (PubMed:12015115, PubMed:23283987).  Component of an integrin containing attachment complex, which is required for muscle development and maintenance (PubMed:22253611).  Involved in the assembly of dense bodies and M lines during body wall muscle development by recruiting several of their components including integrin pat-3, cpna-1, unc-89 and unc-112 to integrin-mediated attachment sites (PubMed:12015115, PubMed:23283987).  Plays a role in distal tip cell (DTC) migration and in oocyte development probably by regulating the actin cytoskeleton (PubMed:16476426).  During the formation of neuromuscular junctions at the larval stage, negatively regulates membrane protrusion from body wall muscles (PubMed:16495308).  May be involved in thermotolerance and lifespan (PubMed:24314125).
What are the official names of this protein?
Integrin-linked protein kinase homolog pat-4, ILK homolog, Paralyzed and arrested elongation at two-fold protein 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, M line. Basal cell membrane; Peripheral membrane protein. Note=Colocalizes in dense bodies and M lines with integrin pat-3. Localization to muscle attachment sites is regulated by pat-2, unc-52 and unc-112 (PubMed:12015115). Co-localizes with pat-3 and pat-6 at body wall muscle attachment sites (PubMed:12781130, PubMed:17662976).
Protein: HS74L_MOUSE
Sequence: MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSTGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPSLDEKPRNVVFIDMGHSAYQVSVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKSVMDQANLQREDINSIEIVGGATRIPAVKEQVTRFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSVTLRWKTSFEEGTGECEVFSKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDPRIGNFTIQNVFPQSDGDSSKVKVKVRINIHGIFSVASASVIEKQNLEGDHNDAAMETEAPKSEGKEDVDKMQVDQEEGGHQKCHAEHTPEEEIDHTGAKAKAPPSDKQDRINQTIKKGKIKSIDLPIQSSLYRQLTQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDKLGTVYEKFITPEDMNKLSAMLEDTENWLYEEGEDQPKQVYVDRLQELKKYGQPIQMKYVEHEERPKALNDLGKKIQLVLKVIEAHRNKDERYDHLDPAEMERVEKYISDSMNWLNSKMNAQNKLSLTQDPVVKVSEIVTKSKELDNFCNPIVYKPKPKVEAPEDKAKTGSEHNGPMDGQSGSETSPDPPKGSSQHTDSGEMEVD
What is the function of this protein?
Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.
What are the official names of this protein?
Heat shock 70 kDa protein 4L, Heat shock 70-related protein APG-1, Osmotic stress protein 94.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May translocate to the nucleus after heat shock.
Protein: CR9AA_BACTG
Sequence: MNQNKHGIIGASNCGCASDDVAKYPLANNPYSSALNLNSCQNSSILNWINIIGDAAKEAVSIGTTIVSLITAPSLTGLISIVYDLIGKVLGGSSGQSISDLSICDLLSIIDLRVSQSVLNDGIADFNGSVLLYRNYLEALDSWNKNPNSASAEELRTRFRIADSEFDRILTRGSLTNGGSLARQNAQILLLPSFASAAFFHLLLLRDATRYGTNWGLYNATPFINYQSKLVELIELYTDYCVHWYNRGFNELRQRGTSATAWLEFHRYRREMTLMVLDIVASFSSLDITNYPIETDFQLSRVIYTDPIGFVHRSSLRGESWFSFVNRANFSDLENAIPNPRPSWFLNNMIISTGSLTLPVSPSTDRARVWYGSRDRISPANSQFITELISGQHTTATQTILGRNIFRVDSQACNLNDTTYGVNRAVFYHDASEGSQRSVYEGYIRTTGIDNPRVQNINTYLPGENSDIPTPEDYTHILSTTINLTGGLRQVASNRRSSLVMYGWTHKSLARNNTINPDRITQIPLTKVDTRGTGVSYVNDPGFIGGALLQRTDHGSLGVLRVQFPLHLRQQYRIRVRYASTTNIRLSVNGSFGTISQNLPSTMRLGEDLRYGSFAIREFNTSIRPTASPDQIRLTIEPSFIRQEVYVDRIEFIPVNPTREAKEDLEAAKKAVASLFTRTRDGLQVNVKDYQVDQAANLVSCLSDEQYGYDKKMLLEAVRAAKRLSRERNLLQDPDFNTINSTEENGWKASNGVTISEGGPFYKGRAIQLASARENYPTYIYQKVDASELKPYTRYRLDGFVKSSQDLEIDLIHHHKVHLVKNVPDNLVSDTYPDDSCSGINRCQEQQMVNAQLETEHHHPMDCCEAAQTHEFSSYIDTGDLNSSVDQGIWAIFKVRTTDGYATLGNLELVEVGPLSGESLEREQRDNTKWSAELGRKRAETDRVYQDAKQSINHLFVDYQDQQLNPEIGMADIMDAQNLVASISDVYSDAVLQIPGINYEIYTELSNRLQQASYLYTSRNAVQNGDFNNGLDSWNATAGASVQQDGNTHFLVLSHWDAQVSQQFRVQPNCKYVLRVTAEKVGGGDGYVTIRDDAHHTETLTFNACDYDINGTYVTDNTYLTKEVVFHPETQHMWVEVNETEGAFHIDSIEFVETEK
What is the function of this protein?
Promotes colloidosmotic lysis by binding to the midgut epithelial cells of insects.  This protein is toxic to Galleria mellonella.
What are the official names of this protein?
Pesticidal crystal protein Cry9Aa, 130 kDa crystal protein, Crystaline entomocidal protoxin, Insecticidal delta-endotoxin CryIXA(a).
What is the protein family that this protein belongs to?
Belongs to the delta endotoxin family.
Protein: HSCB_BORPA
Sequence: MAADDHFSLFGLPARFALDPVQLEQAWRAVAARVHPDRYATASAAERRVAMQWAARANEAYRQLRDPMLRARYLCEQAGVDLQTESNTAMDPAFLMQQMEWREMLDDARRDPAAFAALRAELEQARLRMQQTLSELIDERGDYQQAGTKVREWMFVEKLAQELSAAQPMQ
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: OOSP2_HUMAN
Sequence: MALEVLMLLAVLIWTGAENLHVKISCSLDWLMVSVIPVAESRNLYIFADELHLGMGCPANRIHTYVYEFIYLVRDCGIRTRVVSEETLLFQTELYFTPRNIDHDPQEIHLECSTSRKSVWLTPVSTENEIKLDPSPFIADFQTTAEELGLLSSSPNLL
What is the function of this protein?
Involved in oocyte maturation.
What are the official names of this protein?
Oocyte-secreted protein 2, Placenta-specific 1-like protein, Protein TMEM122.
What is the protein family that this protein belongs to?
Belongs to the PLAC1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DUSC_AZOVI
Sequence: MRIALAPMEGLVDELLRDLLTRVGGIDWCVTEFVRVCDRLLPVAQFEKLAPELRHGWRTRAGTPMHLQLLGSDPACLAENAALAAELGAPAIDLNFGCPAKTSTARGADGCCSTSRNCCMPSSARCAGPCRRCAGDRQDAPGVRPARGRPGVRRALVEGGVAHLVVHARTKVEGYRPPASWEWLARVREAVAVPVYANRKSGRRRIGCREISGVEDVMLGCGLVSRPDLARQIAMRAPDARSSRRAGVRYSRWCASSGGAPGSGSRRATPLAGSSSGWACWRAVIRRRPRCSPNCAGRTTAGGWMPCWA
What is the function of this protein?
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.  Specifically modifies U16 in tRNAs.
What are the official names of this protein?
tRNA-dihydrouridine(16) synthase, U16-specific dihydrouridine synthase, U16-specific Dus, tRNA-dihydrouridine synthase C.
What is the protein family that this protein belongs to?
Belongs to the Dus family. DusC subfamily.
Protein: KDPC_BURA4
Sequence: MKTLIRPLVVIFVVLTVVTGLAYPAVMTVFGQAVFPSQANGSLIEKDGRAVGSALIGQPFDAPKYFWGRLSATSPMPYNASGSGGSNLGPLNPSLAEQVKARIAALRDAGTDLSKPVPVDLVTASASGLDPEITPAAAAYQVERVAKARNLTADTVAQLVAANTAGRQFGVLGEPRVNVLKLNLALDAAQAAH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: AT2C1_HUMAN
Sequence: MKVARFQKIPNGENETMIPVLTSKKASELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASGPELGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEIDAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKKVERSREKIQKHVSSTSSSFLEV
What is the function of this protein?
ATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway (PubMed:16192278, PubMed:30923126, PubMed:21187401, PubMed:12707275, PubMed:20439740).  Within a catalytic cycle, acquires Ca(2+) or Mn(2+) ions on the cytoplasmic side of the membrane and delivers them to the lumenal side.  The transfer of ions across the membrane is coupled to ATP hydrolysis and is associated with a transient phosphorylation that shifts the pump conformation from inward-facing to outward-facing state (PubMed:16192278, PubMed:16332677, PubMed:30923126).  Plays a primary role in the maintenance of Ca(2+) homeostasis in the trans-Golgi compartment with a functional impact on Golgi and post-Golgi protein sorting as well as a structural impact on cisternae morphology (PubMed:20439740, PubMed:14632183).  Responsible for loading the Golgi stores with Ca(2+) ions in keratinocytes, contributing to keratinocyte differentiation and epidermis integrity (PubMed:14632183, PubMed:10615129, PubMed:20439740).  Participates in Ca(2+) and Mn(2+) ions uptake into the Golgi store of hippocampal neurons and regulates protein trafficking required for neural polarity (By similarity).  May also play a role in the maintenance of Ca(2+) and Mn(2+) homeostasis and signaling in the cytosol while preventing cytotoxicity (PubMed:21187401).
What are the official names of this protein?
Calcium-transporting ATPase type 2C member 1, ATPase 2C1, ATP-dependent Ca(2+) pump PMR1, Ca(2+)/Mn(2+)-ATPase 2C1, Secretory pathway Ca(2+)-transporting ATPase type 1, SPCA1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Golgi apparatus, Golgi stack membrane; Multi-pass membrane protein. Note=During neuron differentiation, shifts from juxtanuclear Golgi position to multiple Golgi structures distributed over the neural soma with a predominance in the apical dendritic trunk.
Protein: MIAA_DEIGD
Sequence: MPPVPLLTAPTAAGKSALALALGRQFGLEVIAADAFTVYRGLDIGTAKPTPAERAQVPHHLLDVVDVTEDYDVARYTRAAESAIADVLARGRVPLVVGGTGFYLSALVRGLPLTPPADPQMRAEVEADLAARGLDALLAEVAAANPAEAVRLERNPRRVVRALEVYRRTGRFPGEFGYRPPAFRYRMFAFTHPWPELEARVAARTRTMLAQGWPEEAAWLAQQVAPDQEPRPTVWQALGYREALAVHAGTLDPEAAARQITLATRQYAKRQLTWVRTQLGTSPVTPSQAAEALVAFLSGGGLSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CAPSD_CRV
Sequence: MAMTTTNNNRAMTRAAKQALPALGALATSGMGQQLFMSGVNYAIEKGKQFVPNRRGGKKNRNTDMVAHPGALSGSMAAPVAISRIVRGSKPRFIRSKGSVTITHRELVGQFNSSSALVVNGGITGNLYKINPANAVLFPWLQTLASNFDQYMFNTLRLQYVPMCASTETGRVAIYFDKDSQDLEPVDRIELANMRHLTETAPWCEGSLRVPVDSVKRFMNDNSTVDPKLIDLGQVGLATYGGPGTNAVGDLFIHYTVTFYEPQPSSGLTSTLQTGTGSANAGPTLVAVATTATTTTVTFRSPGTYLVSMVQRATTFTGVTPIALTFNSNTNTTAAGTNYSANYNVTVPVPGAQMRFVGTGFGNYTLQVTRAKITNAATLL
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.
What are the official names of this protein?
Capsid protein, Coat protein, p41.
What is the protein family that this protein belongs to?
Belongs to the icosahedral plant coat protein family.
What are the subcellular locations of this protein?
Virion.
Protein: VATE_SACS2
Sequence: MDFEQLLDKSLNKVREEIKTELSKSLDEAIKLLNEGHNKIVQEYSQRINELIVKTKEEIEGEKARLEVENKRTLLVEKEYWINKVYERVLGKIGEVVKTKEYKDAIENIISKEIKEIREEKVTIYCSPNDKLMIEKIVGNNKNVTVKTDEKMLGGIKIYFERSGLTRDFSLKLILDQVFDSMRGKISDMLFGGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: EF1B_ORYSJ
Sequence: MAVTFTDLHTADGLKALEQHLSGKTYVSGNAISKDDIKVFAAVPSKPGAEFPNAARWYDTVAAALASRFPGKAVGVNLPGGGAASSAAAAAPAAKDADEDDDDLDLFGDETEEDKKAADERAASKASSKKKESGKSSVLLDVKPWDDETDMKKLEEAVRSVQMEGLTWGASKLVPVGYGIKKLQIMLTIVDDLVSVDSLIEEHLTEEPINEFVQSCDIVAFNKI
What is the function of this protein?
EF-1-beta and EF-1-beta' stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta, Elongation factor 1-beta', EF-1-beta', Elongation factor 1B-alpha 2, eEF-1B alpha 2.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: SYP_PYRAB
Sequence: MVERKRWSENFSEWFNEVIEEAGILDKRYPVKGMNVWLPYGLKIMKNIEKFIHEEMERTGHQEVLFPALIPETEFKKEAEHIAGFEGEVFWITHAGHEPLDVKLILRPTSETAMYSMFALWIRSHADLPFKVYQIVNVYRYETKHTRPLIRVREISRFFEAHTAHADFEDAERQIKEDLEIFDNLMKRLAIAYIISKRPEWDKFPGAFYSLGAEVVMPDGRTLQIGTMHNYKQNFAKAYNILYEKEDGTHDYVHQTTFGMSERLLAAVIAIHGDDRGMVLPPTIAPIQVVIVPIPKKEKQEIVYEYAREIEEELRTAGIRVHLDMREKRPGWKFYDWELKGVPVRIEVGPRDVENSTVVLARRDKLEKITIKREELVDKVRELFDDIMKYLYERANEWLNSHIKRVETLEEAKKAFEDRRGIVEIPWCGEESCGLKMEEELDAKMLGIPYPEEKAKAPEGSRCPVCGRDAKFIARFARTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_PSYA2
Sequence: MSNSIDSQSIPTISPTDYTKFDPDTIHEKLDASLSRPQLNTDGSIRHFLGIEGLNKAQLRAIIAKAETFFDDKGQLINRPELEGYTVMNLFFEPSTRTRTTFEVAEKRLGANVLNIDIERSSTKKGESLRDTLWNLQAMTADIFVVRHSASGAAHFMATEVTPDIAIINGGDGWHAHPTQGMLDMLTIHREAPRPFEELSVAIVGDIKHSRVARSDISALQTLGVKDIRVCAPRTLLPKGIERFGVQVYENMNECVTDCDVIMGLRIQNERIGSPLLASSSEYYKHYGITPERMALAKPDAFVMHPGPMNRGVEIASSVADGAQSVILKQVNNGIAIRMAVLSLAMEGQRAHQAAGN
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: VTI1A_DICDI
Sequence: MDVFERTEQNFQHVCNSITRRIKQLPNYGGEKKKIAVREVENDIDEALKFISEMEKLAQNHPQRIKLQTKTKQYHSDIQKYKREVQLAQLQSSNQTNSNPWSNAPDDYQSQYDNQRQHLLQGSNMLDSTSDRLLRTHQISAQSEQIGQNILMDLGKQGEQIRGMRDKLHETDDQIKSARKIMTGIARRLATNKVILSIIILLLMGIIALIICLKWLR
What is the function of this protein?
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane.  These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers.
What are the official names of this protein?
Vesicle transport through interaction with t-SNAREs homolog 1A.
What is the protein family that this protein belongs to?
Belongs to the VTI1 family.
What are the subcellular locations of this protein?
Membrane; Single- pass type IV membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass type IV membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Single- pass type IV membrane protein. Endosome membrane; Single- pass type IV membrane protein. Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: RL7_PARL1
Sequence: MTDLAKIVEDLSNLTVLEAAELSKMLEEKWGVSAAAPVAVAAAGAAPAAAAEEQTEFDVILAAAGDKKIEVIKEVRAITGLGLKEAKDLVEGAPKTVKEAASKDEAAKIKAQLEKAGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GPMI_SHESW
Sequence: MTTTKRPIALLILDGWGYRENTHMNAIFHAKTPVLDRLNAQYPHGLISGSGLDVGLPDGQMGNSEVGHINLGSGRIVYQELTRISKAISDHEFETNPALCDAVDSAINAGGAVHIMGLLSPGGVHSHEEHIEAMCRMAVARGATKVYLHAFLDGRDTPPRSAKASLSHFDDLFTTLGHGRVASIIGRYFAMDRDNRWDRVSQAYELITQGKAKFQYDNAVTALEAAYARDENDEFVSSSAITDVDGKVATLQDGDALIFMNFRADRARQITRSFIHPDFDGFERAVVPKMHFVTLTEYAGDITAPIAYPSENLVNTLGEVLQNRGRTQLRISETEKYAHVTFFFNGGKEEPFEGEDRILINSPKVATYDLQPEMSSTELTDKLVAAIESTKYDVIICNYPNGDMVGHTGNFDAAVKACEAVDTCIGRVVEALAKVGGECIITADHGNAEQMTDETTGQAHTAHTSELVPFIFVGRDATIDKGGKLSDVAPTILQLIGETIPAEMKGKPLIHIKE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RBSA3_RHIL3
Sequence: MMASVPVLEIRNVSKHFGAVKALTEVSFSLEKGEVHALCGENGAGKSTLMNIIAGVLQPTEGDVLVDGAPVKVTSPAVAQSLGLGLVHQEIALCPDATVAENMFMAATNRRRSPFMNYGRLERDAQVVMNRLAPIDVRRKVGDLSISSQQLVEIAKALTLDCRVLIFDEPTAALTESETQVLFAIIRDLKAQGISIIYISHRMAEIFSLCDRVTVFRDGRYVSMEKVADVTPDDVVRRMVGREITQLYPEKQAPAERTDEIILSVRNLGDGSRFTDVNFDLRKGEILGVGGLIGSGRTEIAEGICGLRPVIDGKVQLHGQRLRARSYAQAAQAGVVYLSEDRKGSGIFLDLSIAQNIAVLDLKSLTGPLGLLNSKAEADRAHNLVRRLGVRMGGIDMPVSSLSGGNQQKVAIAKQLAVDPKVILMDEPTRGIDVGAKSEIHRLLRDLARSGIGIVVISSELPELLGLCDRVLVIHEGTVAGEVEGEAMTEEAIMRLASGIGGHNNSKASEHAA
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 3.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSAD_CYACA
Sequence: MQQSLNLKMPSPEFYGNTGGWLRSSDIEEKYAITWSSKNEDIFEIPTGGVAKMKAGDNLLYLAKKEQCLALGNQLKIKFKILNFKIYRIFPNGEAQFLHPKDGVFPEKVNEGRKPIGKIDHNIGKNLNPAEVKFTHKTIF
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.
What are the official names of this protein?
Photosystem I reaction center subunit II, Photosystem I 16 kDa polypeptide, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MOBA_PSE14
Sequence: MNVPAALPPCSILLLAGGRGQRMGGRDKGLIEWQGKALIEHLHRLTRPLTDDLIISCNRNIERYAHYADQLVQDDDADFNGPLAGIRAALPLARHKWLLVLPCDVPLVDEPLLQALREKAVECPERPIMVREGQHWQPLLCMIPIAHAATLEAAWQAGERSPRRALEPLQPVALQLEAGDPRLANLNTPCLLTGISENCGK
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_MYSTU
Sequence: MSLTYMNILVAFVISLTGLLMYRSHMMSSLLCLEGMMLSLFVMVTITILNTHLTLASMMPIILLVFAACEAALGLALLVMVSNTYGVDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HIBCH_XENLA
Sequence: MSFGRLESQLRLKVFGRLQVIRQHLRMSNHTVKDGGCLLTKAGCAGVITLNRPKALNALNLGMIRQIYPQLKLWEEDPETYLVIIKGAGGKAFCAGGDIRAVTDAGKVGDRLAQDFFREEYILNNAIGTCKKPYVAVIDGITMGGGVGLSVHGHFRVASEKTLFAMPETAIGLFPDVGGGYFLPRLTGKLGLYLALTGFRLKGSDVQKAGIATHFVESEKLSSLEQDLVAMKSPSKENVADVLDSYQKKSYAAQDKPFVLAENMDKINSLFSGNTVEEIMENLKCDGSSFAMKQLQTLSTMSPTSLKITFRQLKEGASMSLQEVLTMEYRLSQACMNGHDFYEGVRAVLIDKDQKAKWKPESLEEVTEDYIDSCFTSLGSRDLKL
What is the function of this protein?
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite.  Has high activity toward isobutyryl-CoA.  Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism.  Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity).
What are the official names of this protein?
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HAND2_CHICK
Sequence: MSLVGGFPHHPVVHHEGYPLRRRRCRRRRRHPLRPRGEPLLHGWLISSHPEMSPPDYSMALSYSPEYANGAPGMDHSHYGGVPPGSGPPGLGGPRPVKRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLLPKDDQNGEAEAFKAEIKKTDVKEEKRKKELNEILKSTVSSSDKKTKGRTGWPQHVWALELKQ
What is the function of this protein?
Essential for cardiac morphogenesis.  Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).  Plays an important role in limb development, particularly in the establishment of anterior-posterior polarization of the limb bud.
What are the official names of this protein?
Heart- and neural crest derivatives-expressed protein 2, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHAND.
What are the subcellular locations of this protein?
Nucleus.
Protein: INS2_MOUSE
Sequence: MALWMRFLPLLALLFLWESHPTQAFVKQHLCGSHLVEALYLVCGERGFFYTPMSRREVEDPQVAQLELGGGPGAGDLQTLALEVAQQKRGIVDQCCTSICSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin-2.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.