PharMolix/UniProtQA huggingface dataset:
Protein: PSBF_HUPLU
Sequence: MTIDRTYPIFTVRWLAIHGLAVPTVFSLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RK20_HORVU
Sequence: MTRVPRGYIARRRRTKMRSFASNFRGAHLRLNRMITQQVKRAFVSSHRDRGRQKRDFRRLWITRINAATRVYKVFDSYSKLIHNLYKKKLILNRKMLAQVAVSNPNNLYTISNKIKIIN
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RR7_CUSGR
Sequence: MSRRGTAEKKKAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIMYRAVKTIQQNTEKNPLSVLRQAIRGVTPDLTVKARRVSGSTHQVPIEIRSTQGKALAVRWLLAASRKRPGRDMAFKLSSELVDAAKGRGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, plastid.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid.
Protein: AGL62_ARATH
Sequence: MVKKSKGRQKIEMVKMKNESNLQVTFSKRRSGLFKKASELCTLCGAEVAIVVFSPGRKVFSFGHPNVDSVIDRFINNNPLPPHQHNNMQLRETRRNSIVQDLNNHLTQVLSQLETEKKKYDELKKIREKTKALGNWWEDPVEELALSQLEGFKGNLENLKKVVTVEASRFFQANVPNFYVGSSSNNAAFGIDDGSHINPDMDLFSQRRMMDINAFNYNQNQIHPNHALPPFGNNAYGINEGFVPEYNVNFRPEYNPNQNQIQNQNQVQIQIQNQSFKRENISEYEHHHGYPPQSRSDYY
What is the function of this protein?
Probable transcription factor.  Required for suppression of cellularization and promotion of nuclear proliferation during early endosperm development.  The FERTILIZATION-INDEPENDENT SEED (FIS) polycomb complex is required for suppression of ALG62 expression at the end of the syncytial phase of endosperm development.
What are the official names of this protein?
Agamous-like MADS-box protein AGL62.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS13_THEP1
Sequence: MARIVGVELPNNKKVWVALTYIYGIGRSRSFEILKNTGIDPEKRVGDLTDEEISKITKYIQDHFKVEGELRSEVERNIRRLIEIGCYRGIRHKLGLPVRGQKTRSNARTRKGPRPSRIKTKKKSS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NUOB_BACAH
Sequence: MEKEGVTMVINFEELHPNERAELERNIFFSTLEQLKGWARSNSLWPMTFGLACCAIEMMGVGSSHYDLDRFGSFFRTSPRQSDVMIVSGTVTKKMAPIVRRLYDQMPEPKWVIAMGSCATAGGPYVNSYAVVKGVDQIVPVDVYIPGCPPNPAALIYGINKLKEKIRYEAKTGKQVTNK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYC_PICKU
Sequence: PAPFEQGSAKKGATLFKTRCAQCHTIEAGGPHKVGPNLHGIFSRHSGQAEGYSYTDANKRAGVEWAEPTMSDYLENPKKYIPGTKMAFGGLKKAKDRNDLVTYMLEASK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: MRAY_BARQU
Sequence: MMLFFSSLSDWFPGVSVFRYITFRTVAAMLTSGLIVFLFGPSIIASLKLRQGKGQPIRADGPQTHFKKAGTPTMGGLMILTGIVVSAFLWCNLSNIYFWVSLFVMLSFGMIGFYDDYLKVTKQTEKGFSGKARLSLEFLIAIIAAFVLLQVGSSGLALPFVKDYFINLSWFFLPFSAFVIVGTGNAVNLTDGLDGLAIVPVMVAALSFALIAYLSGNINFADYLQIHYVSGTGELAVLLGAVVGAGLGFLWFNAPPAAIFMGDTGSLALGGLLGIVAVATKHEIVLALIGGLFVLEGFSVVIQVGYFKLKKKRVFLMAPIHHHFEKKGWTESQVVIRFWIISIVLALVGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL20_JANSC
Sequence: MSRTKGGTVTHRRHKKVIDAAKGYYGARSTNFRTATQAVDKANQYATRDRKNRKRQFRALWIQRINAAVRQHDEALTYSRFINGLAKAGIEVDRKVLADLAVHEPDAFSAIVDQAKAAL
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: FLGH_ECO55
Sequence: MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: SECA1_RUEPO
Sequence: MLGLGTLAKKVFGTPNDRKIKATRPVVAQINALEEEFAKLTDEGLKQKTDELRKRALDGESLDALLPEAFANCREAGKRALGLRAFDTQLMGGIFLHQGNISEMKTGEGKTLVATFPAYLNALTGKGVHVVTVNEYLAKRDSEWMGKVFAALGMTTGVIWSGQPDAEKMAAYESDITYATNNELGFDYLRDNMKGELSEVYQKQHNFAIVDEVDSILIDEARTPLIISGPAQDRSDLYVAIDALLPALSDDHFELDEKTRNVTFTDEGNEFLEAQLVARGLLPEGQSLYDPESTTIVHHVNQGLRAHKLFQRDKDYIVRDGEVVLIDEFTGRMMPGRRLSDGLHQAIEAKENAQIQPENVTLASVTFQNYFRLYDKLSGMTGTALTEAEEFAEIYGLGVVEVPTNRPIARTDEDDQVYRTAAEKYGAMIDETKKAHEKGQPVLLGTTSIEKSEMLSQMLTKEGIEHNVLNARQHEREAQIVAEAGRYGAVTIATNMAGRGTDIQLGGNVEMKVLEALAENPEADPVELRAAEEARHAEEKQKVLDAGGLYVMASERHESRRIDNQLRGRSGRQGDPGRTVFYLSLEDDLMRIFGSERLDKVLTTLGMKEGEAIIHPWVNKSLERAQAKVEGRNFDMRKNVLKFDDVMNDQRKVIFNQRREIMATEDLSDVVADMREQVIDDLIDEYMPPKTYADQWDTQGLYAAVIEKLGIDVPVIEWAAEEGVDDDEIRERLIKASGDYMESKAADFGAENMRNIEKQVLLQTIDSKWREHLLKLEHLRSVVGFRGYAQRDPLNEYKTESFQLFEGLLDSLRETVTQQLSRVRMLSEEEQRQMMAQMMAQQNQAEQAAVQAEAVAEAKASGDARPGFVEDDPSTWGNPARNDLCPCGSGKKFKHCHGRLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 1.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: Y986_HAEDU
Sequence: MHKLTPDEAIDIAYDIFLEMAGEHLEPADILLFNLQFEERGAVEMVETSDRWEEEIGTLIDPTAFAEVWVGLVNDKDEMDDVFARFLISHQAENREYHVIWKE
What are the official names of this protein?
UPF0263 protein HD_0986.
What is the protein family that this protein belongs to?
Belongs to the UPF0263 family.
Protein: AIM44_CANGA
Sequence: MSGMIIRTPTRTKTKSFNGKQMDFTFPSPVRGSVDEHSLDNHRIVNETLSLKPQEDIEVSSQMLSDYTSSASNANTYSGNSSNGYYSFANISDNTTASPKLHNHNNMVSPILENTESSFQLQTVESLDPQRQRIRSTYEYGHMGSNQNLRQTREKSKTAESISTTIAQQTIPTADNISFDFSDISGYEDAVSNKSENKNHKPQNSVVKNQLRATSRAAISTNDSPSLSNVYMSSLINSSLESTRKTSTASSSVRSSRSSLKRSNAVRCKGGLLQYFTKLGIKIRKNCNKLRLVMRRKLFRFKKNSKSFSRSNSIRSGLEISKLPKVRHEKKLRQESSSIAPHTLHQKRTHGFNNKLHKSMSLKSLQPALVSETVPEINNNLHDILESKEKTADVPAATKTMKTTPSLRRTPSSIRRAASILTSNVATPKASANNRNSMIEYDTVENSRISSRNSSIKSKGRLVRSSGSVGLSSIARQPSIVVKNKVIPLSMSRFSIKEEIKEEEEESEESTSDYYVETEPVEAAPRTLAGPKSYAPENFRYGANVDDIKTLYKHYLSTVISRRIKMRLEMAQGEHSATNEPALTHQSTASLKDPIASVLTEYDSEGSEGTNLFDDEDDSSASEEDDEVVLPPLKGHNSTMSFVVQSPFTRQNSMASSSALLYLPVKRSLTLPIGMKIT
What are the official names of this protein?
Altered inheritance of mitochondria protein 44.
What is the protein family that this protein belongs to?
Belongs to the AIM44 family.
What are the subcellular locations of this protein?
Bud neck.
Protein: RL11_CYAP4
Sequence: MAKKVVAIIKLAITAGKANPAPPIGPALGQHGVNIMMFCKEYNARTADQAGLVIPVEISVYEDRSFTFILKTPPASVLIQKAAGIERGSGEPNKKKVGKITTAQLREIAQTKLPDLNANDVDAAMRIVAGTARNMGVTIVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RUVC_TOLAT
Sequence: MTIILGIDPGSRITGYGVIRQQAGKVEYLGSGCIRTSGEQLSDKLKQIYDGISEIILQFKPDLFAIEQVFMAKNPDSALKLGQARGSAIVAAVNAGLPVAEYAARQVKQSVVGTGAADKEQVQHMVKQLLKLPACPQADAADALAVALCHSHTQQTLIRMAGKVHGTARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: TIG_MACCJ
Sequence: MSVKWEKQEGNEGVLTVTVPAEEVNAGLDKAFKKVVKQVNVPGFRKGKMPRPMFEQRFGVEALYQDALDFILPDAYAAAVEEAGINPVDRPEIDIEQMEKGKELIFTAKVTVEPEVELGDYKGLEVEKEDTEVTEEDLNKAIEADLARKAELVVKEEGEVAEGDVVNLDFDGYVNEEAFEGGKAEGYDLEIGSGQFIPGFEEQLVGTKVGDEKDVTVTFPEEYHAEELAGKEAVFKVKINEVKSKEVPELDDEMAKELDESVDSVDAYKEKYKKDLQEQKTLQAENNMKESLIAQAVENAKVDIPEAMINTELDRMMQEFEQRIAQQGLNLELYYQFSGQTEEQLKESMKADAEARVKTNLTLAAIAKAENIEISDTDVDAELSKMSEQFGLSVDDIKAALGNGEVLKDDLRIQKAIDVLVKESKEK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: YDER_ECOLI
Sequence: MKRLHKRFLLATFCALFTATLQAADVTITVNGRVVAKPCTIQTKEANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPVETSAVTAIVTGSTDNTGYYKNEGTAENIQIELRDDQDAALKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALINVIYTWQ
What are the official names of this protein?
Uncharacterized fimbrial-like protein YdeR.
What is the protein family that this protein belongs to?
Belongs to the fimbrial protein family.
What are the subcellular locations of this protein?
Fimbrium.
Protein: TRM13_KLULA
Sequence: MMAVTVSGNTGQSTAERLQCEFFLVKKKRQCGMTRRAGSQFCSEHSTDSDRVPCPLDPSHTVCLSKMRVHMRKCNKFRHDVSYQAKQREIPWFKEGLNSISNGKSDSKPADETLVKSVSLIQKIFQNEFGDEPPLPLIEKQNELLERTERYKTLVNRKHARQQSSLIQHLKESKLWPSLESCAVNKTLEYIELGCGRAEFSRYVNIATNLDQKEHSHEKPEYKAVAPSFTLIDRASQRLRFDNKFSSDIGTEVQIRREKIDIKDLRLDAVLHDASQYVAISKHLCGVATDLSLRCLLNSDKCKANLRGILIAMCCRHVCQSSEYVNQEYIKGLLKRQTDGSMAYSEFFQCLKKFCSYCTCGLRPDMDPNSGSEDHITKLTHNERQRIGHMARRIIDEGRAQFLQSKGFETVLFKYTDSAVTLEDTALLALRKHD
What is the function of this protein?
tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
What are the official names of this protein?
tRNA:m(4)X modification enzyme TRM13, tRNA methylase 13.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase TRM13 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: DERPC_BOVIN
Sequence: MKEPRIFPRERPTPWTRAPLPPRGRLDGSLGPQGGPVLNTGHPLGMNSDPFLMASSSLGGNLAPFPRNPSPFPTSSGSLASNPAPFPAGARDPGLASFPRGMNPTSTGAVSFPRPGGLLGPSPGSTLNPRAGALPGPGPLSNPRLGSLPGPGPVSNPRPSGLLGTGPDPRSGGPMGPGSGPSLRAGVLLTPGNGPPNPRPVGLGPGPSPNLRSGFVGTNPAPRSSMFPGPGLGPNPRSSGLGPGLGPNPRAGGLGPGPNLDARAGGLLGTGSGLNLRMAGPQGLDLAPILRAAGLLGANSASFSQASGNMGTSPSSMARLPGPIGPNSGPGSRGIGLPGPNPSPLSRAPGPVGPNSAHFARPAGPMGVNANPFPRGTGSGGLNPAAFSQSSNTLASNPINFQRSAGLQGSSPAVFPRASGPLGPNPANFPRATGLQGPSPATFPRSIGPLGPGQVTFPRPAPRPLGSSPAGPVGINPAPFARPTGTLGVNPASFPRMNGPVSKTLVPFPRVGSLPGTNPAAFPRPGGPMAAMYPNGMLPP
What is the function of this protein?
Potential tumor suppressor.
What are the official names of this protein?
Decreased expression in renal and prostate cancer protein.
What is the protein family that this protein belongs to?
Belongs to the DERPC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASTD_PARXL
Sequence: MSELFIGGEWAAGTGPAFASRNPGTGAAVWEGNSASADDVDRAVRSARRAFAAWSASSVDERCAVVRRFAALVTERKEALAEAIGRETGKPLWEARTEAASMAAKVEISIQAYNERTGEKRSAMADGTAVLRHRPHGVVAVFGPYNFPGHLPNGHIVPALIAGNAVVFKPSELAPGVAALTVQIWRDAGLPAGVLNLVQGEKDTGIALANHRQIDGLFFTGSSDTGTLLHKQFGGRPEIVLALEMGGNNPLVIGPVADVDAAVHHTIQSAFLSAGQRCTCARRIFVPNDAAGDRFLERFTEVTSRITVGEYNADPQPFMGAVISVRAASRLVAAQERLLADGAKALLKMEQRDPKLGFVTPAILDVTNVANRPDEEHFGPLAQIIRYGSFNEALEQANDTEFGLSAGLLADDEALWAHFQRTIRAGIVNWNRPTNGASSGAPFGGPGRSGNHRPSAYYAADYCAFPMASVESAQLQMPASVSPGLQF
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: UVRB_PSELT
Sequence: MFKLVSDYEPTGDQPQAIDRLVEGIKKGYRFQTLIGVTGSGKTFTMANVISRLNRPALVISPNKTLAAQLYGEFKTFFPHNRVEYFISYYDYYQPEAYVPTKDLYIEKNADINDVLVRMRMSALKSVRTRRDVVVVASVSSIYASGDPSDFDRMNIQLSTGLKISPHAVAQHLAKIGYERSNEITVKGCFRLRGDVLEIYPTYQDEGIRIEFFGSVVDRIETFDKLNRSPLEELQKIIIYPAIEFVTTEEKLKRAVESIKNELDQRLTELKNQGKILEAQRLQQRTMHDLELLSALGYCPGIENYSRHFDGRKPGEPPYTLLDYFDDDVLVFLDESHIAVPQLRAMWRGEHSRKKSLVEYGFRLPSAFDNRPLTFEEFLKKVPQIIFVSATPGPFEYQVSEQIVEQIIRPTGLIDPEVEVRPTKYQVDDLISEIKKVVERGERALITVLTKKTAEKLSEYLVEMGIKSLYIHSELDAIERIEVLKKLRRGDVDAVVGINLLREGLDLPEVSLVAILDSDKEGFLRSETTLIQIIGRVARNLNGKVLMYADRVTPAMQRAIDETNRRRKIQMEYNEKYGITPKTIVKPLQIEIFEKFMEKPEIDYHQLAKDLSKEEYLSLLEEEMYRAASELRYEDAAKLRDEIFRLREELKDENYL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YKW2_SCHPO
Sequence: MSESQTESTTVTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCEKNNVKRTDIFLTSKLANCSDYYSTRAAIRSSLHHLGTYIDLFLIQSPAGGKKSRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPLTHGIRLNDEKLVPIAKKLNISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLDVFNFTIPDDVVQELSSFDEHWHAGTTYDPTVCD
What are the official names of this protein?
Uncharacterized oxidoreductase P32A8.02.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: THII_SALPC
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALAQYREQLEGKTFCVRVKRRGKHEFSSIEVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAVHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKVDDGQMGVVLKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAIKAKIEAEEENFDFSILDKVVEEANNVDIREIAQQTQQEVVEVETVSGFGPNDVILDIRSVDEQDDKPLKVEGVDVVSLPFYKLSTKFGDLDQSKTWLLWCERGVMSRLQALYLREQGFANVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP54_METAC
Sequence: MVMEKLGDSLQGALKKLIGAGRIDERTVNEVVKDIQRALLQADVNVKLVMGMSQRIKERAMKEEPPAGMNPREHVIRIVYQELMEIIGKGAEIQLKPQTIMMVGLQGSGKTTSAAKLARYFQRKGLKAGVVAADTFRPGAYHQLKTLAEKLNVGFYGEEGNPDAVEITKNGLKALEKYDIRIVDTAGRHALEADLIEEMERIHAVAKPDHKFMVLDAGIGQQASQQAHAFNDSVGITGVIITKLDGTAKGGGALSAVSETKAPIAFIGVGETPEDFEKFEADRFISRLLGMGDLKSLMEKAEESLSEEDVNVEALMQGRFTLKDMYKQLEAMNKMGPLKQIMSMLPMGMGGMKFSDEMFQATSDKMKNYKVIMDSMTEEEMTDPRVIGGSRIKRISKGSGCSSEDVRELLKYHKTMQTALKGFRGGKFNIQKMMKKKMGM
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: AGLU_SACS2
Sequence: MQTIKIYENKGVYKVVIGEPFPPIEFPLEQKISSNKSLSELGLTIVQQGNKVIVEKSLDLKEHIIGLGEKAFELDRKRKRYVMYNVDAGAYKKYQDPLYVSIPLFISVKDGVATGYFFNSASKVIFDVGLEEYDKVIVTIPEDSVEFYVIEGPRIEDVLEKYTELTGKPFLPPMWAFGYMISRYSYYPQDKVVELVDIMQKEGFRVAGVFLDIHYMDSYKLFTWHPYRFPEPKKLIDELHKRNVKLITIVDHGIRVDQNYSPFLSGMGKFCEIESGELFVGKMWPGTTVYPDFFREDTREWWAGLISEWLSQGVDGIWLDMNEPTDFSRAIEIRDVLSSLPVQFRDDRLVTTFPDNVVHYLRGKRVKHEKVRNAYPLYEAMATFKGFRTSHRNEIFILSRAGYAGIQRYAFIWTGDNTPSWDDLKLQLQLVLGLSISGVPFVGCDIGGFQGRNFAEIDNSMDLLVKYYALALFFPFYRSHKATDGIDTEPVFLPDYYKEKVKEIVELRYKFLPYIYSLALEASEKGHPVIRPLFYEFQDDDDMYRIEDEYMVGKYLLYAPIVSKEESRLVTLPRGKWYNYWNGEIINGKSVVKSTHELPIYLREGSIIPLEGDELIVYGETSFKRYDNAEITSSSNEIKFSREIYVSKLTITSEKPVSKIIVDDSKEIQVEKTMQNTYVAKINQKIRGKINLE
What is the function of this protein?
Major soluble alpha-glucosidase.
What are the official names of this protein?
Alpha-glucosidase, Maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRID1_HUMAN
Sequence: MEALTLWLLPWICQCVSVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHRISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPSASATLHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADNCVSSPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCHQETPKEDKEVNLEQVHRRMNSLMDEDIAHKQISPASIELSALEMGGLAPTQTLEPTREYQNTQLSVSTFLPEQSSHGTSRTLSSGPSSNLPLPLSSSATMPSMQCKHRSPNGGLFRQSPVKTPIPMSFQPVPGGVLPEALDTSHGTSI
What is the function of this protein?
Receptor for glutamate.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.
What are the official names of this protein?
Glutamate receptor ionotropic, delta-1, GluD1, GluR delta-1 subunit.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein.