PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_SYNE7
Sequence: MTETNFDFLAQGDPAIAAIIGRELQRQQEHLELIASENFASPAVMAAQGSVLTNKYAEGLPSKRYYGGCEFVDQAEELAIERAKELFGAAHANVQPHSGAQANFAVFLTLLQPGDTFLGMDLSHGGHLTHGSPVNVSGKWFNAGHYGVNRETERLDYDAIRELALQHRPKLIICGYSAYPRTIDFAKFREIADEVGAYLLADMAHIAGLVAAGLHPSPIPHCDVVTTTTHKTLRGPRGGLILTRDAELGKKLDKSVFPGTQGGPLEHVIAAKAVAFGEALRPEFKTYSAQVIANAQALARQLQARGLKIVSDGTDNHLLLVDLRSIGMTGKVADLLVSDVNITANKNTVPFDPESPFVTSGIRLGTAAMTTRGFKEAEFAIVADIIADRLLNPEDSSMEDSCRRRVLELCQRFPLYPHLSPATPVAV
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABI_BUCAI
Sequence: MGFLKGKKFLIIGISSVRSIAFGIAKSLYNQKAELGFVCQNEKIRKKIKKLVEPMKSCIVLCCDVSNDKNIKKLFIDLGQVWKKFDGLVHAIAYCPKQYFNGDFIDNITREGFNISHEISSYSFIGLVKACRTMLNNFSSLLTLSYLGSQRVVPNYNVMGLAKASLEASVRYMASSLGKENIRVNAISSSPIKTISSYKITNFNKIRNCSYASSFLKNSVTSENIGNVASFLLSDLSLGITGSVIYVDNGFNVSSMNNIQ
What is the function of this protein?
Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis (By similarity).
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI, ENR, NADH-dependent enoyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.
Protein: HMUV_ECOL5
Sequence: MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLLRQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHPHRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLFLDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCVLHDLNLAARYADRVVLMQKGKVIANGKPQDVLTQQALTMLYGADITVLKDPANHSPLIVLDH
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: C1QL2_MOUSE
Sequence: MALGLLIAVPLLLQAAPPGAAHYEMLGTCRMICDPYSVAPAGGPAGAKAPPPGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDSGRPGLPGLQLTTSAAGGVGVVSGGTGGGGDTEGEVTSALSAAFSGPKIAFYVGLKSPHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNGQVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDGGKAHGGNNNKYSTFSGFLLYPD
What is the function of this protein?
May regulate the number of excitatory synapses that are formed on hippocampus neurons.  Has no effect on inhibitory synapses.
What are the official names of this protein?
Complement C1q-like protein 2, C1q and tumor necrosis factor-related protein 10, C1q/TNF-related protein 10, C1qTNF10, CTRP10.
What are the subcellular locations of this protein?
Secreted.
Protein: FABV_PSEAE
Sequence: MIIKPRVRGFICVTTHPAGCEANVKQQIDYVEAKGPVVNGPKKVLVIGSSTGYGLAARITAAFGSGADTLGVFFERPGSESKPGTAGWYNSAAFEKFAHEKGLYARSINGDAFSDEVKRLTIETIKRDLGKVDLVVYSLAAPRRTHPKSGEVFSSTLKPIGKSVSFRGLDTDKEVIKDVVLEAASDQEVADTVAVMGGEDWQMWIDALLEADVLADGAKTTAFTYLGEKITHDIYWNGSIGAAKKDLDQKVLGIRDKLAPLGGDARVSVLKAVVTQASSAIPMMPLYLSLLFKVMKEQGTHEGCIEQVDGLYRESLYGAEPRLDEEGRLRADYKELQPEVQSRVEELWDKVTNENLYELTDFAGYKSEFLNLFGFEVAGVDYEQDVNPDVQIANLIQA
What is the function of this protein?
Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II).  Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).  It can use both crotonyl-CoA and trans-2-decenoyl-ACP.  It is able to convert trans-2-enoyl-ACP of different length (C2 to C16) to the corresponding acyl-ACP.
What are the official names of this protein?
Enoyl-[acyl-carrier-protein] reductase [NADH], ENR, Trans-2-enoyl-CoA reductase, TER.
What is the protein family that this protein belongs to?
Belongs to the TER reductase family.
Protein: DJA7A_ORYSJ
Sequence: MALLQFGGTLAPKLGEKPQLLPRSPALTRVIYADPRFLVSKSGSGGRLKHLVSPTASLQSRTSSRLFNHAPSPRFRHRRSSRFIVRADADFYSTLGVSRNASKSEIKSAYRKLARSYHPDVNKDPGAEQKFKDISNAYEVLSDDEKRSIYDKYGEAGLKGAGMGTGDYSNPFDLFESLFEGFGGMGGMGGRAARNRPMQGDDEAYNLVLNFKEAVFGVEKEIEITRLEGCNTCDGTGAKPGTKPTTCKTCGGQGQVVSSTRTPLGIFQQVSTCNTCGGTGEFSTPCNTCGGDGRVRKTKRISLKVPAGVDSGSRLRVRSEGNAGRRGGPPGDLYVFIDVLSDPVLKRDGTNILYTCKVSYIDAILGTTVKVPTVDGMVDLKIPSGTQPGTTLVMSKKGVPLLGKSNARGDQLVRVQVEIPKRLSSDERKLIEELANLNKAQTANSRR
What is the function of this protein?
Plays pivotal roles in chloroplast development.  Is essential for the regulation of chloroplast development and differentiation.
What are the official names of this protein?
Chaperone protein dnaJ A7A, chloroplastic, Chaperone protein dnaJ A7, OsDjA7.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EX7S_BACCR
Sequence: MENKLSFEEAISQLEHLVSKLEQGDVPLEEAISYFKEGMELSKLCDEKLKNVQEQMAVILGEDGELEPFTALGDEA
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSG4_TRYBR
Sequence: MPTAGAVLLLATAAVLSRPAAAANEKKPLTISAAGAVCGFSNELKEVASFAATKVNAYLTETEQLGTLAVDFCAAIFNGNGKPTAGEVYAALLAAKTQTDRQAQQQKLVTGALLASSLCSQQAGHIESFIHVFYQAHRDATTTCIYKSDEHQRKAADVPCVNNGGGLNKITITTRATKPQLNSKYKAIVAGTTPNGAAAEKNCKLVNGEQSQNVFLASQTTNIALKWGDGLLTVPIGDTAISASNWEPNNKDSIASGNYKECAAALEQVPPRQSTATAAASKLLKLEAEDDPKLEEELISKNSFYGDFPISNVKITATDFSSLHSKLKSYRKKHTADGHQLLKAKLQHLEKQMQMNATACKLGAEISSGEPSTAKTTTSGRCEGKAKTACPKSDYRQREEKDGKEECKPKSGEEQKTQTTGAGEGAADKKEEKCKGKLEPECTKAPECKWEGETCKDSSILVNKQFTLSMISAAFM
What is the function of this protein?
VSG forms a coat on the surface of the parasite.  The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.
What are the official names of this protein?
Variant surface glycoprotein 4, VSG 4, Metacyclic variable antigen.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A soluble form is released from ruptured cells by the action of a PI-PLC.
Protein: MUTL_BACC1
Sequence: MGKIRKLDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAEEDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTGDAPGTHLIIKGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVSLKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLVPIEAESLDFTIKGYVTLPEVTRASRNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPVGRYPIGFLSIEMDPMLVDVNVHPAKLEVRFSKEQELLKLIEETLQAAFKKIQLIPDAGVTTKKKEKDESVQEQFKFEHAKPKEPSMPEIILPTGMDEKQEEPLAVKQPAQLWQPPKQEWQPPQSLVREEQSWQPSTKSIIEEPIREEKSWDSNDEDFELEELEEEVQEIKEIEMNGNDLPPLYPIGQMHGTYIFAQNDKGLYMIDQHAAQERINYEYFRDKVGRVAQEVQELLVPYRIDLSLTEFLRVEEQLEELKKVGLFLEQFGHQSFIVRSHPTWFPKGQETEIIDEMMEQVVKLKKVDIKKLREEAAIMMSCKASIKANQYLTNDQIFALLEELRTTTNPYTCPHGRPILVHHSTYELEKMFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: LAFU_VIBPA
Sequence: MQKQEHVVFKRAKAHGHDEPHGGAWKVAFADFMIALMALFLVLWVMQVVDKEERKAIVAHLHSSSVFDKSYGNPFDTSQSISPIDLAQDSSVPSKHNSNHVVSSYFQGDGDGPEINSLVPGTFDTQEQLAALAKVIEEMTAQINAQGNVNVTVTPQGLRIVLQDDYKQHMFSRGGAELTPFFEDLLLALAPLFEQVTNPLIISGHTDAIPFKKRFGRQSNWALSASRADVARKTLVEGGMPDDRVMQVTGMSDRALLNPDEPDSSENRRIELFILTTPAAKVLETLFGNQDDSELQKAKQKAEFNQPVIRQEVIRYSADAEKQEAKIQAL
What is the function of this protein?
Probable integral membrane protein required for the rotation of the flagellar motor.  Might be a linker that fastens the torque-generating machinery to the cell wall.
What are the official names of this protein?
Chemotaxis protein LafU.
What is the protein family that this protein belongs to?
Belongs to the MotB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: MURA2_STRMU
Sequence: MRKIVINGGKPLKGEVAVSGAKNSVVALIPAIILADDIVTLDGVPAISDVDSLIDIMTLMGASVECDGDSLKIDPRGVKDIPMPYGKINSLRASYYFYSSLLGRFGRAVVGLPGGCDLGPRPIDLHLKAFKAMGATVSYEGEAMRLSTEGKPLKGAHIYMDTVSVGATINTMIAASKAQGRTVIENAAREPEIIDIATLLNNMGAHIRGAGTDMIIIEGVEKLHGTRHQVIPDRIEAGSYIALAAAVGEGIKVTNVLYEHLESFISKLEEMGVRMTIEEDSVFVEKQDKLKAVSIKTSPYPGFATDLQQPITPLLLTAVGRGKIRDTIYEKRVNHVAELARMGAKISVLGGQIIYEGPNELSGAPVKATDLRAGAALVTAGLMAKGQTVITNIEFILRGYSDIIQKLNRLGADIEIVEE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS16_YERPY
Sequence: MVTIRLARGGAKKRPFYQVVVTDSRNARDGRFIERVGFFNPIASGQAEALRLDLDRIEHWIGLGATVSDRVSVLIKDAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL5_AFIC5
Sequence: MAETAYIPRLREVYDRDIRSKLTEQFGLTNVMQVPRLDKVVINMGVGEAVNDRKKVELAAGDLALIAGQKPIVTHSRKAIATFKLREGQAIGAKVTLRKAKMYEFIDRLINVALPRVRDFRGLNPKSFDGRGNYSLGLKEHIVFPEIDYDKSGESWGMDITVCTTAATDEQARALLTAFNFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MNMA_YERE8
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLQQQGYQVAGLFMKNWEEDDGEEYCSAATDLADAQAVCDKLGMELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRQDVNGKSRLLRGLDGNKDQSYFLYTLSHEQLAQSLFPVGELEKPEVRRIAEQLELVTAKKKDSTGICFIGERKFRDFLGRYLPAQPGPIMTVDGQHVGEHQGLMYHTLGQRKGLGIGGTKEGGDDPWYVVDKDVANNILLVAQGHEHPRLMSVGLIAQQLHWVDREPVTAAFRCVVKTRYRQQDIPCTVTPLDDERVEVRFDDPVAAVTPGQSAVFYQGEVCLGGGIIEERYPLPGSVAN
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPPD_ECO57
Sequence: MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLDDAGRPTL
What is the function of this protein?
Part of the ABC transporter DppABCDF involved in dipeptide transport.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Dipeptide transport ATP-binding protein DppD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y923_TREPA
Sequence: MSYSWKVRALCCAGLCVGAGLRAQEGSGIRVRGMPEHAQVTVNGYLCATPEEMVLTPGECEVTVCAFGYTKKTLQVVVEEGSFTVVDGRLDTARLELTDVTAQRAHFNPRDPAGLNTEYVTFRVTKSAKCTVTVKDAEGKXXCEEPVELVELGLNVGGIFGGSNKNSEDVSVSAKVAFEGNVTSDPAMGQLYASALCLYRIVHNNDSSGANKCFMRKGLTFATTCAYGIKGFTVALSGELGASSETGIKKPDFSTDVGLSLKYQNKICSIATYSKCGTTTGSNSDGANSVAGVSVLRAACKSRDGLGEQLRLQRYSYEGWELRASIGYVINTKLRVGRP
What are the official names of this protein?
Uncharacterized protein TP_0923.
Protein: SECB_ANAPZ
Sequence: MQPKIRVRGQYIKDLSFENPNAPKVFLMMSKTPPEINISVNVSSAALPVKPPEGEQASVALYEVALQINIESVVEKLPAFICEIKYCGVFSIEEDEELEQEQVKRALLINAPSILFPFVREVIAKVTSSAGFPPLMLEVIDFSAMYEKQLAENADGEK
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPC_ECOL6
Sequence: MRGLRPALSTFLFLLLITGGVYPLLTTALGQWWFPWQANGSLIREGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKQIAARVAALRAANPDASTNVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIAKYSQQPLVKYIGQPVVNIVELNLALDKLDE
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YKGV_ECOLI
Sequence: MSAFKLPDTSQSQLISTAELAKIISYKSQTIRKWLCQDKLPEGLPRPKQINGRHYWLRKDVLDFIDTFSVRESL
What are the official names of this protein?
Protein YkgV.
Protein: V008_FOWPN
Sequence: MPILLKKQVSEVSCYAITVLGILCLILFTILVVVTCKWYYAFPYFSKVCPDEWIGYNSKCYYFTINETNWNDSKKLCDVMDSSLIRFDNIETLNFVSRYGKGSYWIDINQNRKIPGINFSLYYEQGVNDICLLFDTSNIIEMSCIFHERTICVKEDRYTHWYTEYMR
What are the official names of this protein?
Putative C-type lectin protein FPV008/FPV253, BamHI-ORF2.
Protein: RLMH_STRPB
Sequence: MKVKLICVGKLKERYLKDGISEYQKRLSRFCQFEMIELTDERTPDKASFADNQLIMSKEAQRIHKKIEERDFVIALAIEGKQFPSETFSELISGVTVKGYSTITFIIGGSLGLDSIIKKRANMLMSFGLLTLPHQLMRLVLTEQIYRAFMITQGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_PELPB
Sequence: MPFIVNTASERDEMLKAIGVSSFDDLLVAIPEEIRLKRALDLFPASDEPQVRKLLEGLASANKSTADYVSFLGGGAYDHFIPAAIKTITSRSEFYTAYTPYQAEVSQGTLQAIYEYQSLVCRLYEMDVANASMYDGATALAEAVLMAMNVTGRSKVVVAGKLHPYNSSVLKTYLEAAGHHAVIQNTLEEGVGSIDALKELVGASVAAVVVQQPNFYGSLEDVEAIGAIAHENGALFVVSADPLSLGMLAAPGSYGADIAVGEGQPLGTPQSFGGPYLGIFTVKQQLVRKIPGRLVGMTKDRDGEDGFILTLQTREQHIRREKATSNICSNQALNALQAAIYLSLLGKEGLQQVATQSAQKAHYLAGKIAAIPGFSLKYKAPFFREFVVETPIPAAAVIERMLEHKLFAGHDLAVHGETGLLVAVTEKRTKAELDSFVDKLEGITGI
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: NDC80_CAEEL
Sequence: MFGDRRKTGGLNLNGRASIAITPTKRFTDYTGSTSVRKTDARPSLSQPRVSLFNTKNSSVAPRDVKSLVSLNGSKIYNFLVEYESSDAPSEQLIMKPRGKNDFIACFELIYQHLSKDYEFPRHERIEEEVSQIFKGLGYPYPLKNSYYQPMGSSHGYPHLLDALSWLIDIIRINSAVSEDTQNILFGDFMEQGKAQEKTLNYAWMTSTFRDYTNDRKAAENPSSSYWDDTKHRLRKYFEQSNEFEDMTKTAASALEMLNYECDEIEADKGNEASLKEEISRIRDDIRKAKDYLEQNLHVKQHMEKELAMVKSEQEEKISENEKVQKMVDDLKNKIELQKQIHGLTGKEVRQMNLDNNKDKEVVLEIQSELDRLSKETWKLKDEDFFKEQKSKFIHLAEQIMKILSGLNIQMNLEPLRAPTNERDLKDYWETLNKIWVPEISRQLHQRKLELETEQSRFSNKAVTAEERIQIQSETLCEAKKNEAREERIRRNERDSWKDARKHIEQRYEQLLNEKEVLLKQMKLDGSLEKEIEDETARMSATGEEHIQKRSQLEAGIRQILDLMVVEIAEIENKKIGFHVQCAGIEKAVL
What is the function of this protein?
Acts as a component of the essential kinetochore-associated ndc-80 complex, which is required for chromosome segregation in mitosis and meiosis and spindle checkpoint activity (PubMed:14522947).  Plays a role in kinetochore assembly and recruits the checkpoint protein mdf-2 and the spindly-like protein spdl-1 to unattached kinetochores (PubMed:18765790, PubMed:19109417, PubMed:24231804).  Mediates the formation of end-on kinetochore-microtubule attachments through recruitment of spdl-1 (PubMed:24231804).  The ndc-80 complex synergistically enhances the affinity of the ska-1 complex for microtubules and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020).
What are the official names of this protein?
Kinetochore protein ndc-80, CeNDC-80, Hec1 homolog.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton. Note=Localizes to kinetochores (PubMed:14522947). The NDC80 complex localizes to microtubules.
Protein: URE3_ECO5E
Sequence: MELTPREKDKLLLFTAALLAERRLARGLKLNYPESVALISAFIMEGARDGKSVAALMEEGRHVLSREQVMEGIPEMIPDIQVEATFPDGSKLVTVHNPII
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSC_DEIGD
Sequence: MTATLNQPQVGTGRVVWFTGLSGAGKSTLASALHAELTARGVAVELLDGDAVRENLSKGLGFSKQDRDTNVRRIGFVAGLLAKHGVTVLVSAISPYAETRREVLSTLPNPTEVFVDAPLEVVTERDVKGLYLRALAGEIPHFTGVSDPYEAPQNPDLHLRTDRISVEEGVRQLLAHLGYGA
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: RECF_PSEA6
Sequence: MKLDSVQIRNLRNLQHVTFKPSHGVNFILGINGSGKSSILEAIHYLGFGRSFRTSKHKNVIQNEQESFTVFCECLEDSTTQRLGLSRSINDTVSVSINGIKGNKVSDLVSLLPVQIFTPQSSDILLGAPKLRRKYIDWCLFHVEHSFLTCSNAYSRLLKHNNALCRKQQVGYANPQRVYWTDLLAQYGSELTEFRNAMMTRLIPLITSNLAQFLPEFCVEISYYRGWEKGLELNEALTKSADRDYKNGYISVGPHKADVRFKISGKPAQEVLSRGQLRMLVAALQLATTQCLMSYTQKTCIFLLDDVGAELDAAKREVFIDRLLESNTQLFVTAIEEHQLEFIDKYQNKKMFHVEHGQVREES
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P2C56_ORYSJ
Sequence: MARAAGLRALVGIEAAGRGRRVAASPSPGGTPAASRGLPGWPGFCGVGCGSSSSSSFAPPRMQARRAAGSAARTRSPSQSNGWITGGSASEDGRLSWDYSSFKGRRPSMEDRFSIKMTTINEQTVSLFGVFDGHGGSLAAEYLKEHLFENLVNHPELLRDTKLAISQTFLKTDADFLESVSSNPFRDDGSTAVTAILVGNHLYVGNVGDSRVVALKAGKAVPLSEDHKPNRKDEQKRIEDAGGIVVFDDTWRVNGLLAMSRAFGNRALKHYVKAEPDIQEKVVDESLEYLILATDGLWDVMRNEDAVSLLKAQDGPKAAAMKLTEVAHSRLTLDNITCIVLQFHHGKSTNSN
What are the official names of this protein?
Probable protein phosphatase 2C 56, OsPP2C56.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: VKT4_CRYNI
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSTDRPEFCELPEDSGPCKGLFHVFYYNSDQNQCLEFIYGGCYGNANNFKTIEECKLTCAA
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor nigrescinin-4.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSU72_XENLA
Sequence: MPTAPLRVAVVCSSNQNRSMEAHNILSKRSFNVRSFGTGTHVKLPGPAPDKPNVYDFKTTYEQMYSDLLKKDKELYTQNGILHMLDRNRRIKPRPERFQNCKDYFDLVITCEERVYDQVVEELNSREQETCQPVHVINVDIQDNHEEATLGAFLICELCQCIQHTEDMENEIDELLQEFEDKSGRTFLHTICFY
What is the function of this protein?
May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination.
What are the official names of this protein?
RNA polymerase II subunit A C-terminal domain phosphatase SSU72, CTD phosphatase SSU72.
What is the protein family that this protein belongs to?
Belongs to the SSU72 phosphatase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly in the cytosol.
Protein: RR19_CHLVU
Sequence: MARSLKKAPFVANHLLEKVERLNTQGDKKVIKTWSRSSTIVPLMIGHTIAVHNGREHIPVFITDQMVGHKLGEFAPTRTFRGHVKKDKKSKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.