PharMolix/UniProtQA huggingface dataset:
Protein: SP0M_BACSU
Sequence: MSFFKKLAASAGIGAAKVDTILEKDAYFPGEEVQGTVHVKGGKIAQDIRYIDLQLSTRYVIVKDDEEHRKYATIHSFRVTGSFTIQPGEEHQFPFTFTLPLDTPITVGKVEVAVVTDLDIQGGIDKSDHDRIFVEAHPWIENVLEAIENLGFRLNEADCEQAPYFQRRLPFVQEFEFVPTSGYYRQMLDELELIFLLDEDGLEIIFEVDRRARGLRGWLEEMYNDGEQLVRVRFSQSELEDTEELEEVLEEILDQYAE
What is the function of this protein?
Controls the expression of spo0A and is required to pass the morphological stage 0 of sporulation.
What are the official names of this protein?
Sporulation-control protein spo0M, Stage 0 sporulation protein M.
What is the protein family that this protein belongs to?
Belongs to the spo0M family.
Protein: RPOC2_MORIN
Sequence: MEVLMAERADLVFRNKVIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFRQATATSISLGIDDLLTIPSKGWLVQDAEQQRLILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPFNPVHMMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIQGISVSPPNGMMPERIFIQTLIGRVLADYIYIGSRCIAVRNQDIGIGLVNRFITFQTQPISIRTPFTCKSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPSNGKIKFNEDLVHPTRTRHGHPAFLCSIDLYVTIESEDIIHNVTIPPKSFILVQNDQYVESEQVIAEIRAGTYTFHFKERVRKHIYSDSEGEMHWSTDVYHAPDFTYSNVHLLPKTSHLWILSGGSYKSSVVPFSIHKDQDQTNVYFLSAAKGKARNSFSVNNDQDQGKHKFFTSGLSGKKESGIPDYSEFNRILDTDHSNLIFPSILHKDSDLFLLAKRRRNRFIIPFQWIQEREKELWPRSSISIEIPINGIFRKNSILAYFDDLQYRRKGSGITKYGAIGLHSILKKEDLIEYGGVKEFKPKYQTKVDQFFFIPEEVHILPESFSIMVRNNSIIGVDTRITLNTRSRVGGLVRVEKKNKRIELKIFSGDIHFPVEMDKIFRHSGILIPPGRVKKEFKESKKWKNWIYVQSITPTKKKYFVLVRPVIIYEIADGINLETLFPQDPLQEKDNLELRVVNYILYGNGKPILGISGTCIQLVRTCLVLNWDQGNKSSSSEETHASFVEVSTRDLIRDFLRINLVKSHISYIRKRNDPLGSVLISDNRSDRTNPFYSIYSKEKIRQLLKENQGTIHTLLNRSKESQSLIILSSSNCFEMGPFNDVKHYNVIKESIKRDPLIPIRNSLGPLGTACQVANFYYILKTHNQISVTKNLQLENLKQTFQVLKYYLMDENGRIYNSDPCSNILFNPFNLNWHFLHHNYCEKKSTIISLGQFFFENVCITKHGPHLKSGQVIIVQIDSVVIRSAKSYLATPGATVHGHYGEILSEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISMNLEKRVEGWNERITRILGIPWGFLIGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEDGMSNVFLPGELIGLFRAERTGRALKEAICYQAILLGITKASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGMIPVGTGFKGLVHRSKQHNNIPLETKKKNLFECEMRDILFHHKELFDFCISTNIHDTSEHLFLGFNDS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL14_HALWD
Sequence: MEALKADVTKGLERGSLVTCADNTGARELKVISVMGSSGTKNRHPKAGIGDQVTVSVTKGTPEMRRQVLEAVIVRQRKSIRRPDGTRVKFEDNAAVIIDEMEEPRGTEIKGPIAREVAERFGSIASTATMIV
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: XYND_RUMFL
Sequence: MKKSIFKRYAAAVGLMASVLMFTAVPTTSNAADDQKTGKVGGFDWEMWNQNYTGTVSMNPGAGSFTCSWSGIENFLARMGKNYDDQKKNYKAFGDIVLTYDVEYTPRGNSYMCIYGWTRNPLMEYYIVEGWGDWEPPGNDGVDNFGTTTIDGKTYKIRKSMRYNQPSIEGTKTFPQYWSVRTTSGSRNNTTNYMKDQVSVTKHFDAWSKAGLDMSGTLYEVSLNIEGYRSNGSANVKSISFDGGIDIPDPEPIKPDENGYYLKENFESGEGNWSGRGSAKVKSSSGYDGTKGIFVSGREDTWNGASINLDELTFKAGETYSLGTAVMQDFESSVDFKLTLQYTDADGKENYDEVKTVTAAKGQWVDLSNSSYTIPSGATGLVLYVEVPESKTDFYMDGAYAGVKGTKPLISISSQSVDPPVTEPTNPTNPTGPSVTKWGDANCDGGVDLSDAIFIMQFLANPNKYGLTGTETNHMTNQGKVNGDVCEHGSGLTEDDAVSIQKYLIRAISELPESYLEGHDPSKTTTTTTRITTTTTTTTTTTTSKTTTTTTTTSPAMHGGYRDLGTPMNTSATMISDFRTGKAGDFFASDGWTNGKPFDCWWYKRNAVINDGCLQLSIDQKWTNDKNPDWDPRYSGGEFRTNNFYHYGYYECSMQAMKNDGVVSSFFTYTGPSDDNPWDEIDIEILGKNTTQVQFNYYTNGQGKHEKLYDLGFDSSEAYHTYGFDWQPNYIAWYVDGREVYRATQDIPKTPGKIMMNAWPGLTVDDWLKAFNGRTPLTAHYQWVTYNKNGVQHSSQGQNPWG
What is the function of this protein?
Contains two catalytic domains with xylanase and endo-beta-1,3-1,4 glucanase activities.
What are the official names of this protein?
Xylanase/beta-glucanase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the glycosyl hydrolase 16 family.
Protein: RIN2_MOUSE
Sequence: MSAWTMGAQGLDKRGSFFKLIDTIASEIGELKREMVQTDISRENGLEPSETHSMVRHKDGGYSEDKDGKTCPRDSGYDSLSNRLSILDRLLHTHPIWLQLSLSEEEAAEVLQAQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEGSGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADNKPLNSPPPHRPLPSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLFLKVHSQDLSTGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSMPETVNHSKHGNVALLGTKPTPIPPPRLKKQASFLEAESSAKTLTARRPSRRSEPEPELELELEMGTAGHAGGAPPRDAPGDCTRAPPPGSESQPPPCHGARQRLSDMSLSTSSSDSLEFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKMSGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIRQFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHTADGSWKQLKENLQLVRQRNPQELGVFAPTPDLMELEKIKLKFMTMQKMYSPEKKVMLLLRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHGEGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNYLRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEDPEEYSLFLFVDETWQQLAEDTYPQKIKAELHSRPQPHIFHFVYKRIKSDPYGVIFQNGEDLTPS
What is the function of this protein?
Ras effector protein.  May function as an upstream activator and/or downstream effector for RAB5B in endocytic pathway.  May function as a guanine nucleotide exchange (GEF) of RAB5B, required for activating the RAB5 proteins by exchanging bound GDP for free GTP (By similarity).
What are the official names of this protein?
Ras and Rab interactor 2, Ras interaction/interference protein 2.
What is the protein family that this protein belongs to?
Belongs to the RIN (Ras interaction/interference) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEF2A_RAT
Sequence: MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVEALNKKEHRGCDSPDPDTSYVLTPHTEEKYKKINEEFDNMMRNHKIAPGLPPQNFSMSVTVPVTSPNALSYTNPGSSLVSPSLAASSTLAESSMLSPPPATLHRNVSPGAPQRPPSTGSAGGMLSTTDLTVPNGAGNGPVGNGFVDSRASPNLIGNTGANSVGKVMPTKSPPPPGGGSVGMNSRKPDLRVVIPPSSKGMMPPLNAQRISSSQATQPLATPVVSVTTPSLPPQGLVYSAMPTAYNTDYSLTSADLSALQGFTSPGMLSLGQASAWQQHHLGQAALSSLVAGGQLSQGSNLSINTNQNINIKTEPISPPRDRMTPSGFQQQQQQQPQQQPPPQPPQPQPQPRQEMGRSPVDSLSSSSSSYDGSDREDPRGDFHSPIVLGRPPNAEDRESPSVKRMRMDTWVT
What is the function of this protein?
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes.  Also involved in the activation of numerous growth factor- and stress-induced genes.  Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival.  Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription.  In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation.  Associates with chromatin to the ZNF16 promoter (By similarity).
What are the official names of this protein?
Myocyte-specific enhancer factor 2A.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMJ_SALCH
Sequence: MQICLMDETGATDGALSVLAARWGLEHDEDNPMALVLTPQHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLTRGYADADIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHRQKSALVKKEMRVFQSLVGPDLDADGLLEPARQLATKRVVVKRPDYAPPLADVATPNAVVTKGHRFDIYAGTPLTE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A_CRYNJ
Sequence: MSSGGKGKASSETKSSSRSSKAGLQFPVGRIHRLLKKGNYAQRIGSGAPVYLAAVLEYLAAEILELAGNAARDNKKSRIVPRHLQLAVRNDEELNKLLGSVVISQGGVLPHIMAELLPVKTKGKAKASQEV
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ANX4_FRAAN
Sequence: MATLVSPPNFCAKEDAEALRKSVKGWGTNEKAIISILGHRNAGQRKEIRAAYEQLYQEDLLKPLESELSGDFEKAVYRWTLDPADRDAVLANVAIKKSTDVYNVIIEISCIHSPEELLAVRRAYQLRYKHSVEEDLAAHTTGDIRKLLVALVTAYRYDGHEINAKLANSEADILHDAIKDKAFNHEEIIRILSTRSKTQLMATFNKYRDDQGISISKNLLEEGANDFQKALHTAIRCLNDPKKYFEKVLRNAIKRVGTDEDALTRVIVTRAERDLRDIKEVYYKKNSVPLEQAVAKDTSGDYKAFLLTLLGKED
What are the official names of this protein?
Annexin-like protein RJ4.
What is the protein family that this protein belongs to?
Belongs to the annexin (TC 1.A.31.1) family.
Protein: RLMF_SHEON
Sequence: MPKPAIKTAAKPATSPAGKRAKPNTPQSVAKLKASTAKAASKPKAKLGEKKTLHPRNVHLHGYDFVALMASFPKLKAFVRPTAYGALSIDFADPLAVKNLNAALLKQHYQIDFWDIPKGALCPPIPGRVDYVHYLADLLFEGATAPRVEQVCALDIGTGANGIYAILGQQVYGWQFVASDINPQSLANVQRIIDNNSCLQGHVTLRRQRDENAIFKGIIEAADRFELTLCNPPFHASLREASEGSQRKVRNLQLSRGEKPKATGASLNFGGQAAELWCQGGEKQFLATMIRESHMFAEQCLWFTSLVSKQENLKPCYQALAKLGVDTVKTIEMQQGNKVTRVLAWSFHSQAKRLRWRSELVTPTE
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEPA_ECOLU
Sequence: MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLSLGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPTLWKPEIFSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MINE_SALPK
Sequence: MALLDFFLSRKKSTANIAKERLQIIVAERRRSDAEPHYLPQLRKDILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEESK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: COX3_NEOMO
Sequence: MTHQTHAYHMVNPSPWPLTGALSALLMTSGLAMWFHFNSVTLLTLGLTTNMLTMYQWWRDIIRESTFQGHHTPTVQKGLRYGMILFIISEVLFFTGFFWAFYHSSLAPTPELGGCWPPTGISPLNPLEVPLLNTSVLLASGVSITWAHHSLMEGNRNHMLQALFITIALGVYFTLLQASEYYEAPFTISDGIYGSTFFVATGFHGLHVIIGSTFLIVCFFRQLKFHFTSNHHFGFEAAAWYWHFVDVVWLFLYVSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: VATE1_MACFA
Sequence: MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQTQRLKIMEYYEKKEKQIEQQKKIQMSNLMNQARLKVLRARDDLITDLLNEAKQRLSKVVKDTTRYQVLLDGLVLQGLYQLLEPRMIVRCRKQDFPLVKAAVQKAIPMYKIATKNDVDVQIDQESYLPEDIAGGVEIYNGDRKIKVSNTLESRLDLIAQQMMPEVRGALFGANANRKFLD
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit E 1, V-ATPase subunit E 1, Vacuolar proton pump subunit E 1.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
What are the subcellular locations of this protein?
Apical cell membrane; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein.
Protein: ATA1_SYNY3
Sequence: MDFPTLSSYLHHHRPGEDILADLHTDPGLGLTAEAVAQRYEQYGRNELKFKPGKPAWLRFLLQFHQPLLYILLIAGTVKAFLGSWTNAWVIWGVTLVNAIIGYIQEAKAEGAIASLAKAVTTEATVLRDGQNLRIPSQDLVIGDIVSLASGDKVPADLRLLKVRNLQVDESALTGEAVPVEKAVELLPEETPLAERLNMAYAGSFVTFGQGTGVVVATANATEMGQISQSMEKQVSLMTPLTRKFAKFSHTLLYVIVTLAAFTFAVGWGRGGSPLEMFEAAVALAVSAIPEGLPAVVTVTLAIGVNRMAKRNAIIRKLPAVEALGSATVVCSDKTGTLTENQMTVQAVYAGGKHYEVSGGGYSPKGEFWQVMGEEVDNVLLDGLPPVLEECLLTGMLCNDSQLEHRGDDWAVVGDPTEGALLASAAKAGFSQAGLASQKPRLDSIPFESDYQYMATLHDGDGRTIYVKGSVESLLQRCESMLLDDGQMVSIDRGEIEENVEDMAQQGLRVLAFAKKTVEPHHHAIDHGDIETGLIFLGLQGMIDPPRPEAIAAVHACHDAGIEVKMITGDHISTAQAIAKRMGIAAEGDGIAFEGRQLATMGPAELAQAAEDSCVFARVAPAQKLQLVEALQEKGHIVAMTGDGVNDAPALKRADIGIAMGKGGTEVARESSDMLLTDDNFASIEAAVEEGRTVYQNLRKAIAFLLPVNGGESMTILISVLLALNLPILSLQVLWLNMINSITMTVPLAFEAKSPGIMQQAPRNPNEPLITKKLLHRILLVSLFNWILIFGMFEWVNRTYDDLALARTMAIQALVAARVIYLLSISQLGRSFLGYVTGKRQTITKASILLLGIAVAIALQIGFSQLPFMNVLFKTAPMDWQQWAICLLPMIPMVPVAILANRLDP
What is the function of this protein?
Could mediate calcium influx.
What are the official names of this protein?
Cation-transporting ATPase pma1.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: QUTA_EMENI
Sequence: MSSDTRQTSGGNARSKRRLTDAVDEDGRPTATAEDPTSNPKRQRVSRACDSCRSKKDKCDGAQPICSTCASLSRPCTYRANPKKRGLPTGYIRTLELLWGLVFNKIQGSEEVVRTLLRAANIPSHLATMGKESEGSDTLLSSWKNSIVLKEIERLLTFLEQPEGDQERSARGEIDSPADAEESSVLSPETLEWQLPDSIAVASQSPLASGPSPVRLPRPSTTRLVRDSGTQTIPLGEIEDLTTNGSSHDRPVIASNSAREEHRLPPNPWPLLDIYFSYTQCWFPILEKHDILRTAFRQGDDDQYNSPSAAGDNAALWAVLALASIQQTSISTTRQLSDLPEDRPDPDQLYAKARSLIPTESGTYQLGHIQALLILSLIKLGQQDCAAAWMLVGQAVRSAQSLGLNDPSDATGVEKTAGRSKHVFLGCFVLETLVAAKLGLLPSLRKTDLTKVGLINEDGLEEWHPWEDQTGLRPIESSRSFQRGPLHALSTFNRLLSLMCILNELCCVRQTPANSMSYLGTLERQLQLWVSALPTSYRIDLQTVSTKPASPHIFGLEMMYEAVATAISLQLAVQKNERNGLRRASEGSKRLVSLLQAYMETYSLSATCPTFGIALTLGLPLPCMKKTAPWAFEASHGINHKLQSFSAHLATVWIHNTGSQRRPRHATQQGTHPRSPMAISLPGNNMRLTNLIEESRTGNLSTTDSYLSPTWMRTSNDENAVLSLPTPASSLNIASGVETNPTSQQITHQHRSSVVGKPNSALIMSDLTTPFPASGHHYQQTYDDASLHFNSLADIESTSSAQRPRIAPDLDALFDELASLDGTDR
What is the function of this protein?
Transcription activation of genes for enzymes and proteins of quinate metabolism by binding to a 16 base-pair sequence (consensus 5'-GGATAANNNNTTATCC-3') in front of each qut gene.
What are the official names of this protein?
Quinic acid utilization activator.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOZ_ACIB3
Sequence: MARVTVEDCLDHVDNRFELVLVASKRARQLARQGMEPTVEWDNDKPTVVALREIAVGHVTKEILKQREQDYQTSSLDLALSTNSLNLEGFSF
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ACCH4_ARATH
Sequence: MESTDRSSQAKAFDEAKIGVKGLVDSGITEIPALFRATPATLASLKSPPPPKHLTIPTVDLKGASVVEKIGEAAEKWGLFHLVNHGIPVEVLERMIQGIRGFHEQEPEAKKRFYSRDHTRDVLYFSNHDLQNSEAASWRDTLGCYTAPEPPRLEDLPAVCGEIMLEYSKEIMSLGERLFELLSEALGLNSHHLKDMDCAKSQYMVGQHYPPCPQPDLTIGINKHTDISFLTVLLQDNVGGLQVFHEQYWIDVTPVPGALVINIGDFLQLITNDKFISAEHRVIANGSSEPRTSVAIVFSTFMRAYSRVYGPIKDLLSAENPAKYRDCTLTEFSTIFSSKTLDAPKLHHFKI
What are the official names of this protein?
1-aminocyclopropane-1-carboxylate oxidase homolog 4.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: DNLJ_METS4
Sequence: MAAQTTRPVEEITAEEARAAHEALSAEIAEHDRRYHGEDAPIISDAAYDSLRRRLEAIEERFPDLAGTGAASASVGAKASDKFAKVRHAVPMLSLGNAFADEEIEEFVERVRRFLGLPASESLAVTAEPKIDGLSLSLRYEGGRLVTAATRGDGEVGEDVTANVRTIREVPERLAGPDVPEICEVRGEVYLSHADFAAINARQEEAGKPLFANPRNAAAGSLRQLDPSITASRPLRFFAYAAGEMSTWPAETQSGLIAAFRRFGLPVNPRTTRCTSVAEMLAHYRAIETERADLGYDIDGVVYKVDSFALQRRLGFVARAPRWALAHKFPAQRAVTTIEAIEINVGRTGSLNPLARLRPVTVGGVVVSNATLHNEDYVRGIDADGTPIRSGINIWDGFALRTDVDLSRGSDVRVGDTVVVLRAGDVIPKVADVVLERRPADAVPYRFPEICPACGSHAVRSYNPRTGKLDSVRRCTGGLICPAQGQERLKHFVSRNALDIEGFGETSITTLFEAGLVRQPADLFRLDFAPLKAAIVARRQALSAERALASGKAPEARKTKAKASEEDKAIRNLLAAVEARRVVPLNRFIFALGIEQVGEATAKALAKHFPDMPALMEGVRAAAAHQPGPDWVGLAALNRVGPTTRERLLAAAEAGETDLLAEGTVARLSAAQKEALLEAYGSPEGVRAAVMRACRQRPGDAYRHLADDSEIGAVTTASLIQFFSEAHNVAAVEALLAQVRTERAAPPAAAAAFSGRTVVFTGSLERMTRSEAKATAERLGAKVSGSVSAKTDLVVAGPGAGTKLKDAEKHGVRVISEAEWLAMVEAA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: HEMA_I51A0
Sequence: MKARLLILLCALSATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGKCNIAGWILGNPECESLLSNRSWSYIAETPNSENGTCYPGDFADYEELREQLSSVSSFERFEIFPKERSWPKHNITRGVTAACSHAKKSSFYKNLLWLTEANGSYPNLSKSYVNNKEKEVLVLWGVHHPSNIEDQRTLYRKENAYVSVVSSNYNRRFTPEIAERPKVRGQAGRMNYYWTLLEPGDKIIFEANGNLIAPWYAFALSRGLGSGIITSNASMDECDTKCQTPQGAINSSLPFQNIHPVTIGECPKYVRSTKLRMVTGLRNIPSIQSRGLFGAIAGFIEGGWTGMVDGWYGYHHQNEQGSGYAADQKSTQNAINGITNKVNSVIEKMNTQFTAVGKEFNKLEKRMENLNKKVDDGFLDIWTYNAELLVLLENERTLDFHDSNVKNLYEKVKNQLRNNAKEIGNGCFEFYHKCDNECMESVKNGTYDYPKYSEESKLNREKIDGVKLESMGVYQILAIYSTVASSLVLLVSLGAISFWMCSNGSLQCRICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: Y338_SPHAL
Sequence: MFSTTTNNIEGHPVREYLGIVTGEVIVGANLFRDLFASITDIVGGRSGKYEDVLARARKEALGEMEAEAAKLGGNAVIGVDIDYEVLGQNGSMLMVSASGTAVVI
What are the official names of this protein?
UPF0145 protein Sala_0338.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: CP2U1_MOUSE
Sequence: MSSLGDQRPAAGEQPGARLHVRATGGALLLCLLAVLLGWVWLRRQRACGIPPGPKPRPLVGNFGHLLVPRFLRPQFWLGSGSQTDTVGQHVYLARMARVYGNIFSFFIGHRLVVVLSDFHSVREALVQQAEVFSDRPRMPLISIMTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKEAMQKHGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINICPWFYYLPFGPFKELRQIERDISCFLKNIIREHQESLDASNPQDFIDMYLLHMEEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQKKVHEEIERVIGCDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQTFTFALPEGSEKPVMTGRFGLTLAPHPFNVTISKR
What is the function of this protein?
A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).  Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids.  May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes.  May down-regulate the biological activities of N-arachidonoyl-serotonin, an endocannabinoid that has anti-nociceptive effects through inhibition of fatty acid amide hydrolase FAAH, TRPV1 receptor and T-type calcium channels.  Catalyzes C-2 oxidation of the indole ring of N-arachidonoyl-serotonin forming a less active product 2-oxo-N-arachidonoyl-serotonin.
What are the official names of this protein?
Cytochrome P450 2U1, Long-chain fatty acid omega-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein. Mitochondrion inner membrane; Multi-pass membrane protein.