PharMolix/UniProtQA huggingface dataset:
Protein: PH4H_HUMAN
Sequence: MSTAVLENPGLGRKLSDFGQETSYIEDNCNQNGAISLIFSLKEEVGALAKVLRLFEENDVNLTHIESRPSRLKKDEYEFFTHLDKRSLPALTNIIKILRHDIGATVHELSRDKKKDTVPWFPRTIQELDRFANQILSYGAELDADHPGFKDPVYRARRKQFADIAYNYRHGQPIPRVEYMEEEKKTWGTVFKTLKSLYKTHACYEYNHIFPLLEKYCGFHEDNIPQLEDVSQFLQTCTGFRLRPVAGLLSSRDFLGGLAFRVFHCTQYIRHGSKPMYTPEPDICHELLGHVPLFSDRSFAQFSQEIGLASLGAPDEYIEKLATIYWFTVEFGLCKQGDSIKAYGAGLLSSFGELQYCLSEKPKLLPLELEKTAIQNYTVTEFQPLYYVAESFNDAKEKVRNFAATIPRPFSVRYDPYTQRIEVLDNTQQLKILADSINSEIGILCSALQKIK
What is the function of this protein?
Catalyzes the hydroxylation of L-phenylalanine to L-tyrosine.
What are the official names of this protein?
Phenylalanine-4-hydroxylase, PAH, Phe-4-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Protein: PURL_WOLSU
Sequence: MENLASLLKSHKLSQADYEHIVQILGREPNLVELGVFSAMWSEHCSYKSSKKYLRGFPTEAAWVIQGPGENAGVIDIGEGYAAVFKMESHNHPSFIEPYQGAATGVGGIMRDVFTMGARPVASLNAIRFGDIRRQDEIGKKHRYLLKGVVAGIGGYGNCMGVPTVGGEMSFEDCYNGNILVNAFTLGIAKSDEIFYGRAEGIGNPVIYVGSKTGRDGLGGAVMSSDSFDDAANQLRPTVQVGDPFAEKLLLEACLELFKTNYIVGIQDMGAAGLTSSSFEMAGRSGSGMIMHLDRVPMREQGMTPYELMLSESQERMLICAKKGYEEKVLEIFRKWELDAEVIGEVTSSGKMELFWHGEKCAEIPVLPVSEEAPMLDRPTKEPAYLAEIRSKGAQAPKEIDLKEAFMKLWSAPETMDKSWVYSQYDSMVQTNTIVGPGGGDGSLVRVKENGAALAMSADCNPRYCYLNPREGAKLAVAESGRNVAVRGARPLAITDCLNFGSPENPEVMWQFAEACEGIKEACKVLLTPVVSGNVSLYNQTNGVDIFPTPSIATVGLLPKAQKALLGAFKKEGNLLLLVGETKSEFGGSLYQKEVEGFLGGDAPVIDLHRELALWRFLEEANEAGFLESAKDVNVGGLAIALGKMSVLGQKGCKVKTALKGVDLFSESPSRAVLEVSSEHLAALESLAQKGGVALGVIGSVGGENLEIDSLSLPLQTLQEIYLRGFAKIVENL
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATG_CITLI
Sequence: MTSNRGQGGIQQLLAAEQEAQHIVAAARNAKMARLKQAKEEAEREIAEYRAQVEREFQRKLAESVGDSGANVKRLEQETEVKIHHLKAGAEKIQYDVVQMFLKHVTTVKN
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase).  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit G, V-ATPase subunit G, Vacuolar proton pump subunit G.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase G subunit family.
Protein: RRF_HELPG
Sequence: MLQAIYNETKDLMQKSIQALSRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNTRQDANNKVKKLEKDKEISEDESKKAQEQIQKITDEAIKKIDESVKNKEDAILKV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_ACHLA
Sequence: GHKLGEFAPTRTFRGHKKEDKKVKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: OR1M1_HUMAN
Sequence: MEPRNQTSASQFILLGLSEKPEQETLLFSLFFCMYLVMVVGNLLIILAISIDSHLHTPMYFFLANLSLVDFCLATNTIPKMLVSLQTGSKAISYPCCLIQMYFFHFFGIVDSVIIAMMAYDRFVAICHPLHYAKIMSLRLCRLLVGALWAFSCFISLTHILLMARLVFCGSHEVPHYFCDLTPILRLSCTDTSVNRIFILIVAGMVIATPFVCILASYARILVAIMKVPSAGGRKKAFSTCSSHLSVVALFYGTTIGVYLCPSSVLTTVKEKASAVMYTAVTPMLNPFIYSLRNRDLKGALRKLVNRKITSSS
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1M1, Olfactory receptor 19-6, OR19-6, Olfactory receptor OR19-5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECB2_GLUOX
Sequence: MSQTYADTVTGTPASLDVSDSLPSSSSLIIGSQYLRTLSIDVQNTPDVYRELPSQPHIGMMVDVTGRQLGDQPTFEVSLVIRAQGFERAPTQDAPNPKVLYELSVAYAGLFGLTGRIPQDAIEPLLLVEAPRFLFPPARSVMLNTVREAGFPSPNIQPIDFHELWQSRRAQQR
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA (By similarity).
What are the official names of this protein?
Protein-export protein SecB 2.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EASC_TRIVH
Sequence: MAPNAADKCPVMGNSGEKCPVMSSSTQSRGPRDIYTLEALSHFNREKIPERAVHAKGTGAYGEFEVTADISDICNIDMLLGVGKKTQCVTRFSTTGLERGSSDGVRDLKGMAVKFFTEQGDWDWVSLNFPFFFIRDPAKFPDMIHSQRRDPQTNLLNPNMTWDFVTKNPEALHMTLLQHSDFGTMFTWRTLSSYVGHAFKWVMPDGSFKYVHFFLASDRGPNFTDGSTAKVDPNDPDFATKDLFEAIERGDYPSWTANVQVVDPKDAPKLGFNILDLTKHWNLGTYPKGLDTIPSRPFGKLTLNRNVKDYFSEVEKLAFSPSNLVPGVEPSEDPILQARMFAYPDAQRYRLGIDHLKAPLRRKETACQHDLGPEFEKWLSQVTSEAWSHPHEDDYKFAREYYEVLPEFRSQEFQDRMVENLCKSIAPGPEELRKRVYDTFELVSSELARRLREGAEAIVAEKARPDSPSRAQPGQLRL
What is the function of this protein?
Catalase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:22403186).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:22403186).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (PubMed:22403186).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:22403186).  Chanoclavine-I aldehyde is the precursor of ergoamides and ergopeptines in Clavicipitaceae, and clavine-type alcaloids such as fumiclavine in Trichocomaceae (PubMed:22403186).  However, the metabolites downstream of chanoclavine-I aldehyde in Arthrodermataceae have not been identified yet (PubMed:22403186).
What are the official names of this protein?
Catalase easC, Ergot alkaloid synthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: RL32_KLEP3
Sequence: MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHITADGFYRGRKVIAK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: OLA1_CAEEL
Sequence: MPPKKNVVEEKPALIGRLGTNLKVGILGLPNVGKSTFFNVLTKSEAQAENFPFCTIDPNESRVAVQDDRFDWLVNHYKPASKVPAFLNVTDIAGLVKGASEGQGLGNAFLSHVSACDALFHLCRAFDDDDVTHVEGEVDPVRDLEIISNELFAKDLQFIDGPLDKVEKLFTRANDKTKKIEYDTLVRVKKCLEEKKPVRQELWNEKEIEILNKHLFLTAKPIVYLVNLSEKDYIRKKNKWLPKIKAWIDTNDAGAVLIPFSGAFELKLLDMPEDERQKYLKEQGVTSNLDKIVHTGYKALQLEYFFTSGEDEVKAWTIQVGTPAPKAAGRIHTDFEKGFIMAEVMKVADLIELGDEAKCKAGGKYRQQGKTYIVQDGDVIFFKFNAGAGLQAKKK
What is the function of this protein?
Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency.  Has lower affinity for GTP.  Plays a role in regulating starvation-induced thermotaxis responses in AFD thermosensory neurons (PubMed:35675262).
What are the official names of this protein?
Obg-like ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_CHLCH
Sequence: MLAKRIIPCLDVRDGRVVKGINFEGLRDAGSILEQARFYNNELADELVFLDISASLESRRTTLEEVMKVSEEVFIPLTVGGGISSVERAREVFLHGADKVSVNTAAVNDPYLISRIAEKYGSQAVVVAIDIKKVGNHYMVHTHSGKQITQYEALEWALKVQELGAGEILLTSMDRDGTKEGYENNSLRMISTAVHIPVIASGGAGNLEHLYDGFSKGCADAALAASIFHFRHYSIRQAKEYLHKRGVAVRF
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_LIMRD
Sequence: MTTIIDGKALAKKINSQTKELVAQLKEKQNIIPGIAVVIAGDDVASLIYTRNKHNKAIKLGINSVLKKFPADVSQAELLAEIEKLNHDDTIDAILVQQPLPPQLDPEVITNAILPTKDVDGLNPLNLGKLFANQHGNYPVACTPRGIMRMLAEYNIDLQGKNAVIVGRSILVGKPLLALLNNANATVTMAGRSTGDLSALTKTADILIVATGVPNLIKATDVKPGAVVIDVGINRLSNGKLTGDVDFEAVKTKAQAITPVPGGVGPMTIATLMEQTVDLAWWRHHG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MPRB_MYCSK
Sequence: MTLPPPPSRLKPPRNTSSLSLRWRVMLLAMSMVAMVVVLMSVAVYAVVSRALYDDIDNQLHSRARLLIESGSLAADPGKAIEGTAYSDVNAMLVNPGRSIYTANQQGQTLPLGEAEKDVISGELLLSLRTANHQRILAVHLTNGSSLLISKSLAPTGQVLGRLGTVLLIVGGVGVAVAAIAGGMVARAGLRPVGRLTQAAERVARTDDLRPIPVFGSDELARLTEAFNMMLRALTESRERQARLVSDAGHELRTPLTSLRTNVELLMASQAPGAPRLPEEEMAGLRADVIAQIEELSTLVGDLVDLTRDEAGGVVYETVDMAEVVDRSLERVRRRRNDIEFDVNVVGWQVYGDAAGLARAVLNLLDNAAKWSPPGGRVGVRLTQTDPVHAELVVSDQGPGIPEAERRLVFERFYRSTAARAMPGSGLGLAIVKQVVLKHGGALRVEDTVPGGNPPGTSFYVMLPGRPLTPGGNGTAPVPAAQFDPDMRSAGSRADRRVIKNTETNGKSRSASKEL
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).
What are the official names of this protein?
Signal transduction histidine-protein kinase/phosphatase MprB, Mycobacterial persistence regulator B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TXB4A_SCOMO
Sequence: MFFKLVLVSAVAIQALSMSILKSNVKRDQKQLQPCQENQICHEVPNSKYEAPPLVHCLCTGGKRCPMDTSLAHKTTGSGDTLMYLFRCI
What are the official names of this protein?
U-scoloptoxin(11)-Sm4a, U-SLPTX(11)-Sm4a.
What is the protein family that this protein belongs to?
Belongs to the scoloptoxin-11 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PECA_MYCTU
Sequence: MSFLVVVPEFLTSAAADVENIGSTLRAANAAAAASTTALAAAGADEVSAAVAALFARFGQEYQAVSAQASAFHQQFVQTLNSASGSYAAAEATIASQLQTAQHDLLGAVNAPTETLLGRPLIGDGAPGTATSPNGGAGGLLYGNGGNGYSATASGVGGGAGGSAGLIGNGGAGGAGGPNAPGGAGGNGGWLLGNGGIGGPGGASSIPGMSGGAGGTGGAAGLLGWGANGGAGGLGDGVGVDRGTGGAGGRGGLLYGGYGVSGPGGDGRTVPLEIIHVTEPTVHANVNGGPTSTILVDTGSAGLVVSPEDVGGILGVLHMGLPTGLSISGYSGGLYYIFATYTTTVDFGNGIVTAPTAVNVVLLSIPTSPFAISTYFSALLADPTTTPFEAYFGAVGVDGVLGVGPNAVGPGPSIPTMALPGDLNQGVLIDAPAGELVFGPNPLPAPNVEVVGSPITTLYVKIDGGTPIPVPSIIDSGGVTGTIPSYVIGSGTLPANTNIEVYTSPGGDRLYAFNTNDYRPTVISSGLMNTGFLPFRFQPVYIDYSPSGIGTTVFDHPA
What is the function of this protein?
Aspartic protease that processes the lipase LipY and other PE_PGRS proteins.  Can also cleave itself.
What are the official names of this protein?
PE cleavage protein A, PE-PGRS family protein PE_PGRS35.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
What are the subcellular locations of this protein?
Secreted. Cell surface. Note=Secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: CASP3_ARALL
Sequence: MDIEKAASRREEEEPIVQRPKLDKGKGKAHVFAPPMNYNRIMDKHKQEKVSAAGWKRGVAIFDFVLRLIAAITAMAAAAKMATTEETLPFFTQFLQFQAEYTDLPTMSSFVIVNSIVGGYLTLSLPFSIVCILRPLAVPPRLFLIICDTAMMGLTMMAASASAAIVYLAHNGNSSSNWLPVCQQFGDFCQGTSGAVVASFIAATLLMFLVILSAFALKRST
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 3, AlCASP3.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: Y316_MYCPN
Sequence: MYNLKNIYASITLYPHEINLVVSDNNNQFHVLYENSIANDELYTHAGITNKAKFKVVLNQLINNANDYLGFKLEKVIVVLAELVDDLEINRFKTDVFFTGYDFNHQDMLSSEKNRFLLKNRHINPNEVLDLVALNYRDLTTDKISKNFKYNCSYRANVIYYTTKNSLVKELKPFLKRNIIVKIDKIVTHHMVLAHSIKQINKNNLFVYLGEHTTDLMLFMDNALVDLVSEPFGRVNFLESDNDSENKALLEFLVDSTARIGDSGSIGMAYTDGSTYKEIRAVTIDDLIQSVNEKTKYLIDFINTNTEIFFQKYGFLPSTLLFYTKSKQLLNNFQLNQNLLSNHFKTVTIFKNEVQFVSRKYLLNCQTIALSWRQDQINVNPTSFALPFYSDKIEKQFKKSFLMLKVHTHINKLVQKLIK
What are the official names of this protein?
Uncharacterized protein MG223 homolog.
Protein: EFCB6_MOUSE
Sequence: MKRNGTRLNFAKANSTKSGSTRARDLMNKMSIIPEWHSLYSNTRKLPCSRPHSSPCKMQRTIFQDLCRPSSSTTAIANPVLSYLDIERILAQKISSRRDDIKKVFQILDRNHNQMVTKGDLKRVITAFLIPLTKDQFQDLLAQIPISSLGNVPYLEFLSRFGGGIDININGIKRVNENEVDNRRTVKEVQLTEKIFRNMRSIRKVFQVMDVNNTGLVQPQELRRVLETFCLRMQDGDYEKFLEQYNIDKTTAVDYNAFLKNLSVKNDASFKYLLSNAAELSRETQQGKNGKRLLDTGSSEDVWKNYSLDDLEKTFCQEFSKSYEKIEKALSAGDPSKGGYISLNYLKVVLDTFIYRLPRRIFIQLIRRFGLKTSTKINWKQFLTAIYERQKLEVSKTLPLKKRSSTEARNRSRKENIIKKLFKYSEDRYTALKKTLLIISSTPSGHITWEELRHILNCMVAKLNDSEFSELKQTFDPEGTGAVRVNSLLDVLDDSTKVRKMSPSTDTKTPLPVAWDSVEELVLDSITRNLQAFYSMLQSYDLRDTGTIGKNNFRKVMRVFCPYLSNEHLVRFSSKFQEAGSGRILYKKFLLSIGVGIPPPTPPLSSPKVQLSDQFQIEEPGQQDERTQPSGEKTSEINNMTKEEVIDGLKHRIQQKDPVFRKQFLSISKEPDVKINQEEFRKVLERSGMPMNDCQYAMLASKLGFKNEEGMSYQDFTMGFEDCMLSGLETVPLQSRTASRTNMDEHFISAEECLRIFPKKLKESFRDVYSAFFRIDLDRDGIISMHDFHRLLQYLQLNMVDLEFERFLSLLGLRLSVTLNFREFQNLCEKRPWKSDEAPQRLIRCKQKVADSELACEQAHQYLIMKAKTRWADLSKNFIETDNEGNGILRRRDIKNSLYGFDIPLTPREFEKLWQNYDTEGRGYITYQEFLHRLGIRYSPKVHRPYKEDYFNFLGHFTKPKQVQEEIQELQQISEREKLMNHYEEISKAFNAMEKSKPVALCRVQKVLQECGCPLKEEELISLLKSLDVSVHNNHIDPVEFLRALEISWASKARPKEKEESSPPPISFSKVTPDEVIKTMQEVVESSQPALVEAFSALDKEDTGFVKAMEFGDVLRSVCQKLTDNQYHYFLRRLRLHLTPNIHWKYFLENFSTFQDETADDWAENMPKAPPPMSPKETAHRDIVARVQKAVASHYHTIVQEFENFDTLKSNTVSRDEFRSICTRHIQILTDEQFDRLWSELPVNAKGRLKYQDFLSKLSIERVPSPPMAAGDSGESTMAQRGSSAPEFSQGTRSNLYSPPRDSRVGLKSRSHPCTPVGTPPLQNCEPIESRLRKQIQGCWRELLRECKEKDTDKQGTISAAEFLALVEKFKLDISREESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKAKETSLMRRMRIQNADKMKEAGMETPSFYSALLRIQPKIVHCWRPMRRSFKTYDKNGTGLLSVADFRKVLRQYSINLSEEEFFHVLEYYDKSLSSKISYNDFLRAFLQ
What is the function of this protein?
Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.  Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
EF-hand calcium-binding domain-containing protein 6, DJ-1-binding protein, DJBP.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, cilium axoneme.
Protein: YL645_MIMIV
Sequence: MSRKSNKQSNPKRNYKNDNYFQENSYTMTNGFTKDKDGKPVEFKKYHRRRKDPYDYSSDEEPFDEQFQNEIKKNIQKNFKKFGNNNFNPNFNPNFNPNFVPEFSSGFPTGFGPDFNFRNQEDSDSEYSDECLTDECSDNYNKQSTDSNKPKSYYIRRKKSGSKKSIPKESIPQQSVIGEKISENFDNTVPIPQNDTTNSQPKSPKPSKSKSSSKSSKSNKSNKSSKSNKSSKSSKSKSNKHSKHKNKSDSSSDSDEKTHKHKDRRHRRGRCTYPQFYDFIPPMPEIPGMPEMPDFFNQTPFNPNNPNFNCGCNQSRPRKSSHDRHKHHNKHKHHNGHHNNPHYHNNNLNFNTNNQFPFDANNFNNQLFSNIFDPNNFNPQNYQTYSGCPSCNVPNSNYGPNNFRPNY
What are the official names of this protein?
Uncharacterized protein L645.
Protein: FHOD3_HUMAN
Sequence: MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHRLLQAPHKLDDCTLQLSHNGAYLDLEATLAEQRDELEGFQDDAGRGKKHSIILRTQLSVRVHACIEKLYNSSGRDLRRALFSLKQIFQDDKDLVHEFVVAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGVINRNETIQWLYTLIGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVTAVDTKRGVKPWSNIMEILEEKDGVDTELLVYAMTLVNKTLSGLPDQDTFYDVVDCLEELGIAAVSQRHLNKKGTDLDLVEQLNIYEVALRHEDGDETTEPPPSGCRDRRRASVCSSGGGEHRGLDRRRSRRHSVQSIKSTLSAPTSPCSQSAPSFKPNQVRDLREKYSNFGNNSYHSSRPSSGSSVPTTPTSSVSPPQEARLERSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFRYKYLEQLAAEEHEKELRSRSVSRGRADLSLDLTSPAAPACLAPLSHSPSSSDSQEALTVSASSPGTPHHPQASAGDPEPESEAEPEAEAGAGQVADEAGQDIASAHEGAETEVEQALEQEPEERASLSEKERQNEGVNERDNCSASSVSSSSSTLEREEKEDKLSRDRTTGLWPAGVQDAGVNGQCGDILTNKRFMLDMLYAHNRKSPDDEEKGDGEAGRTQQEAEAVASLATRISTLQANSQTQDESVRRVDVGCLDNRGSVKAFAEKFNSGDLGRGSISPDAEPNDKVPETAPVQPKTESDYIWDQLMANPRELRIQDMDFTDLGEEDDIDVLDVDLGHREAPGPPPPPPPTFLGLPPPPPPPLLDSIPPPPVPGNLLVPPPPVFNAPQGLGWSQVPRGQPTFTKKKKTIRLFWNEVRPFDWPCKNNRRCREFLWSKLEPIKVDTSRLEHLFESKSKELSVSKKTAADGKRQEIIVLDSKRSNAINIGLTVLPPPRTIKIAILNFDEYALNKEGIEKILTMIPTDEEKQKIQEAQLANPEIPLGSAEQFLLTLSSISELSARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAKAFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNLCQMERRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLFMGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDSGKFSGSSPAPPSQPQGLSYAEDAAEHENMKAVLKTSSPSVEDATPALGVRTRSRASRGSTSSWTMGTDDSPNVTDDAADEIMDRIVKSATQVPSQRVVPRERKRSRANRKSLRRTLKSGLTPEEARALGLVGTSELQL
What is the function of this protein?
Actin-organizing protein that may cause stress fiber formation together with cell elongation (By similarity).  Isoform 4 may play a role in actin filament polymerization in cardiomyocytes.
What are the official names of this protein?
FH1/FH2 domain-containing protein 3, Formactin-2, Formin homolog overexpressed in spleen 2, hFHOS2.
What is the protein family that this protein belongs to?
Belongs to the formin homology family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. SUBCELLULAR LOCATION: [Isoform 4]: Cytoplasm, myofibril, sarcomere, Z line. Note=Threonine phosphorylation in isoform 4-specific sequence TDTDEEEEVE is required for targeting to myofibrils in cardiomyocytes.
Protein: PTH_MYCPN
Sequence: MDKLRLVVGLGNLGKQYAETRHNAGFKVIDRLLSLYHVQLEERNNLGEFILLRKHKVVLAKPNTYMNHSGKFVKWACQNWNIKPDKVMVVYDELAFPLGTVRLKMQGSANNHNGIKSVIAHLNTEHFNRLRFGIKSDNTSNILHEVVMSEFTPAERNLLETALTKAIEALKGYIDGVTMLKLMEVFNA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPY_CHLMU
Sequence: MRFLFAFILLCSPWVSEASQNIVTVKTIHEVASDILYDNTNYWLILDIDDVLFEGAEALSHSSWFERSIQGMRALGASEKEAWEAIYPEWLAIQHQGSIKQIETAIPLLITKVQNQDKIVFAYSERQLCAQNVTFEQLATINLSFDKPNLPYASLPPSISFTKGVLFGAEIHKGLGLQLFLDAQPDLPEKIIYIDNEKYNVMRVGEVCNQKNIPYLGIIYTAPKYLSPTYLPDIAKVQYLFRQKLLSNEAAALLLRHRLDK
What are the official names of this protein?
Putative outer membrane protein TC_0650.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: RS6_RHOP2
Sequence: MPLYEHVFLARQDASTQQVEELTTQITGVIEGLGGKVTKTEAWGLRSLTYRMNKNRKAHFVLLNIDGPSAVVSEIERQERINEDIVRYLTVRVDEHEEGPSAMMRKADRDRERDDRGPREGGFRGDREGRGDREGGGFRGDRGPRRPREDADTAAASEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: G6PI_BACTN
Sequence: MISLNIEKTFGFISKEKVSAYEAEVKAAQEMLEKGTGEGNDFLGWLHLPSSISKEHLADLNATAKVLRDNCEVVIVAGIGGSYLGARAVIEALSNSFTWLQDKKTAPVMIYAGHNISEDYLYELTEYLKDKKFGVINISKSGTTTETALAFRLLKKQCEDQRGKETAKKVIVAVTDAKKGAARVTADKEGYKTFIIPDNVGGRFSVLTPVGLLPIAVAGFDIDKLVAGAADMEKACGSDVPFAENPAAIYAATRNELYRQGKKIEILVNFCPKLHYVSEWWKQLYGESEGKDNKGIFPASVDFSTDLHSMGQWIQEGERSIFETVISLDKVDHKLEVPFDEANLDGLNFLAGKRVDEVNKMAELGTQLAHVDGGVPNMRIVLPELSEYNIGGLLYFFEKACGISGYLLGVNPFNQPGVEAYKKNMFALLNKPGYEEESKAIQAKL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_BACFN
Sequence: MEQRIKFPRSEKVYLSGKLFPEIRVGMRKVEQVPSTTFEGEKKVITPNPHVYIYDTSGPFSDPDIEIDLKKGLPRLREEWILNRGDVEQLPEISSEYGRMRRDDGSLDHLRFEHIALPYRAKAGRHITQMAYAKQGIVTPEMEYVAIRENMNCEELGIETHITPEFVRQEIAEGRAVLPANINHPEAEPMIIGRNFLVKINTNIGNSATTSSIDEEVEKAMWSCKWGGDTLMDLSTGENIHETREWIIRNCPVPVGTVPIYQALEKVNGKVEDLTWELYRDTLIEQCEQGVDYFTIHAGIRRHNVHLAEKRLCGIVSRGGSIMSKWCLVHDRESFLYEHFDDICDILAQYDVAVSLGDGLRPGSTHDANDEAQFAELDTMGELVVRAWEKNVQAFIEGPGHVPMHKIRENMERQIEKCHNAPFYTLGPLVTDIAPGYDHITSAIGAAQIGWLGTAMLCYVTPKEHLALPDKEDVRVGVITYKIAAHAADLAKGHPGAQVRDNALSKARYEFRWKDQFDLSLDPERAFSYFHAGRHTDGEYCTMCGPNFCAMRLSRDLKKTQKQK
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: DID2_BITGA
Sequence: MIQVLLVIICLAVFPYQGSSIILESGNVNDYEIVYPKKVTVLPTGAMNSAHPCCDPVTCKPKRGEHCISGPCCRNCKFLNAGTICKKTMLDGLNDYCTGVTPDCPRNPNKGESDELEWSAAATGSVLM
What is the function of this protein?
The heterodimer bitisgabonin-2 preferentially inhibits the adhesion of the alpha-4/beta-1 (ITGA4/ITGB1) and alpha-9/beta-1 (ITGA9/ITGB1) integrins to VCAM-1 and acts also as a strong antagonist of alpha-5/beta-1 (ITGA5/ITGB1).
What are the official names of this protein?
Disintegrin gabonin-2, Bitisgabonin-2.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.