PharMolix/UniProtQA huggingface dataset:
Protein: RS3_BUCCC
Sequence: MGQKVHPNGMRLGIIKSWNSIWFASKKEFSNYLDSDFKVRSYVKKKLIKASVSKVIIERLSKNIRVTIYTARPGIVIGKKGEDVEKLRIEIAKITGVPAQVNISEIRKPELDAKLVADNISSQLERRVMFRRAIKRSVQNAMRQGAKGIKIEVSGRLGGVEIARREWYREGRVPLHTLRANIEYNTSEAHTTYGIIGVKVWIFKGEILDGMLVVSNKKDKKPFISVKKVSQKYRK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: YCAP_ECOLI
Sequence: MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRGVRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLEDLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQISVYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMKAGEKQLCPRCANPEWTKASRAKRVT
What are the official names of this protein?
UPF0702 transmembrane protein YcaP.
What is the protein family that this protein belongs to?
Belongs to the UPF0702 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PAFA_STRRD
Sequence: MDRRIFGLENEYGVTCTFRGQRRLSPDEVARYLFRRVVSWGRSSNVFLRNGARLYLDVGSHPEYATPECDNVVELVTHDKAGERILEGLLVDAEKRLREEGIAGDIYLFKNNTDSAGNSYGCHENYLVGRHGEFGRLADVLIPFLVTRQIVCGAGKVLQTPRGAVYCVSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERFRRLHVIVGDSNMSETTMLLKVGATDLVLRMIEAGTVMRDLSLENPIRAIREVSHDMTGRRRVRLANGREASSLEIQQEYLSKARDFVDRRGGDEISHRVLELWERTLNAVETGNLDLVAREIDWVTKYQLIERYRKKYDLPLSSPRVAQLDLAYHDVHRRRGLFYLLQKRGAVERVASDLKIFEAKSVPPQTTRARLRGEFIRKAQEKRRDFTVDWVHLKLNDQAQRTVLCKDPFRSVDERVDKLIAGM
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: PROF1_SOYBN
Sequence: MSWQAYVDDHLLCDIEGNHLTHAAIIGQDGSVWAQSTDFPQFKPEEITAIMNDFNEPGSLAPTGLYLGGTKYMVIQGEPGAVIRGKKGPGGVTVKKTGAALIIGIYDEPMTPGQCNMVVERPGDYLIDQGY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-1, GmPRO1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RPOC_AMOA5
Sequence: MLARKDTRVKSDFSEIIISLASPESILERSRGEVTQPETINYRTYKPEMKGLFCERIFGPVKDWECHCGKYKRIRYKGIICDRCGVEVTEKKVRRERTGHIELVIPVAHTWYFRSLPSKIGNLLGFPTKKLDQIIYYERYVVVQPGIKAEEGLSYMDFLTEEEYLDILDSLPRENQLLDDSDPKKFIAKMGAEALEFMLSRIDLDTLSSELREQAHTDTSQQRRIEALKRLKIVEAFRDAKTRIANRPEWMVMRIIPVIPPELRPLVPLDGGKFATSDLNDLYRRVIIRNNRLKRLIDIKAPEVILRNEKRMLQEAVDSLFDNSRKVNTVVAEGSRVLKSFSDILKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHECGLPKDMAAELFKPFIIRRLIERGIVKTVKSAKKLVEKKTPVVWDILENVLKGHPILLNRAPTLHRLSIQAFQPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSHEAIAEASLIMLASHNILNSANGTPLAVPTKDMILGLYYLTKGRKSTPEHPVKGEGMTFFSAQEVIIGIDTGQVSIHALVKVKIKDKDEQGETIEHIVDTIAGRVVFNQYVPEELGFINELLTSKKLQHITSQVYRLVGTSRATQFLDDVKSLGFRNAYKAGVSFALDDIKVPTIKFELIEQAQREVNAVQENYLMGLITDNERYNQIIDIWTRVNTQVTVFLMQELEEDRQGFNSIFMMMNSGARGSREQVRQLGGMRGLMGKPQKQLQGSVGEIIENPILSNFKEGLDVLEYFISTHGARKGLADTALKTADAGYLTRRLVDVAQDVITTEEDCGTLRGVTITTSINKDEVAESISERTLGRISLNDIYDPVTNNLLVNAGEEITEEIAAYIESVGIESIEVRSVLTCETRRGICTKCYGRNLSTGKLVQIGEAVGVIAAQSIGEPGTQLTLRTFHVGGAASSIGVESNIQATDKGVLQFEDFNTIKTTNPQGEQLDVIISRSCEVRLLNPQDNRILMHKHVPYGAYLRVKQGELIEKGQEICYWDPYNAVILTSIDGEIEFHSIEEGITYKEEYDEQTGYKEKVIIESKDKTKNPSITVKGSSGEAINYNIPVKARLIVEDGTKIKAGHPLVKIPRVVSLSKDITGGLPRVTELFEARDPSNPSIVSEIDGFVTYGPIKRGSREIFVESKDGIRRKYLVPLSKHILVQDNDYIKAGYPISDGNTSPSSILHIKGPIAVQEYIAKELQAVYRLQGVKINDKHIEVIIRQMLSKLEVIESGDTTFLPGQTVSKFTFREGNDQLLDKKVVIDAGSSSVLRVGQIITARALHEENSNLKRDKLSLVQARDAQPAIARLKLQGITQASLDTKSFISAASFQDTTRVLSEAAIRGKRDRLQGLKENVIVGHLIPTGTGLPRYSKMIIGLREDYENLVASREKQAATDNI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MLTC_CROS8
Sequence: MKKIFALALIAPLLISCSSKKNAENAYNEAWIKDTNGFDILMGQFAHNIENIWGFNEVLIAGPKDYVKYTDQYQTRSHINFDEGTITVETIAGTEPAARLRRAIITTLLMGDDPGSIDLYSDVNDIQISREPFLYGQVVDNTGQPIRWEGRASKFADYLLQTHLKSRSNGLRIIYSVTINLVPNHLDKRAHKYIGMVRQASRKYGVDESLILAIMQTESSFNPYAVSHADALGLMQVVQHSAGKDVFRSQGKWGTPSRSYLFDPQSNIDTGTAYLAMLNNVYLGGITNPTSRRYAVITAYNGGAGSVLRVFSSDKDQAVNIINQLSPGDVYETLTNRHPSAESRRYLYKVNTAQKMYRRK
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y737_HAEIN
Sequence: MTGAQLIMACLKAHHVTTLFGYPGGAIMPTYDALYDAGLDHLLCRNEQGTAMAAIGYARSTGKVGVCIATSGPGATNLVIGLGDAMMDSIPVVTITGQVASPLIGTDAFQEADVLGLSLACTKHSFIVQSADVALQGDLIQALNALKQDLDIEPWREQIRNFKAKLDFTYVENQGNRPIDPWALLNSLSNRKPNNAIICTDVGQHQMWLVQHILRVARHCGFTVTTMEMTLIETQVRLKITVKSDRTLDLLVNQLVKLPDVLMVN
What is the function of this protein?
Truncated acetolactase synthase; no longer catalytically active.
What are the official names of this protein?
Putative uncharacterized protein HI_0737.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: OADB_PASMU
Sequence: MESILSLLRGMGIMHLELGQALMMLISLVLLWLAIARKFEPLLLLPIGFGGLLSNIPEAGLAMSALESLLHQGSAEQIAIIAAKLNTVADPVAIKEALANAVPSVQNQLEVMAGDMGYNAGVLALFYKVAIGYGVAPLIIFMGVGAMTDFGPLLANPRTLLLGAAAQFGIFATIIGALLLNWTGIISFTLPQAAAIGIIGGADGPTAIYLSSKLAPELLGAIAVAAYSYMALVPLIQPPIMRALTTQAERKIKMVQLRNVSNREKILFPIVLVTLVALLLPDAAPLLGMFCFGNLLRTSGVVERLNDTAQNALINIVTIFLGLAVGSKLVADKFLQPQTLGILLLGVVAFCIGTASGVIMAKFMNKICKHPINPLIGAAGVSAVPMAARVANKVGLEEDHQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVSALM
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Probable oxaloacetate decarboxylase beta chain.
What is the protein family that this protein belongs to?
Belongs to the GcdB/MmdB/OadB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y3459_BURA4
Sequence: MTPSEFRQSVRSGAFRQPTAGQCGPFAQANLAILPNAYAHDFLRFCQANPKACPLLGVGEPGAFRLDVLGEDLDIRTDVPSYNVYRDGRLTERVESLEALWRDDFVVFAIGCSFSFEDMLAREGIALRHIEEGRNVPMYRTSIPNRRAGIFGGQLVVSMRPLRGADAIRAVQITSRFPGVHGAPVHIGHPRELGIADLGAPDFGDAVTVRDGELPVFWACGVTPQTALMEAKLPLAIAHTPGYMLMTDITNASLAVF
What are the official names of this protein?
Putative hydro-lyase BamMC406_3459.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: UPP_LACLS
Sequence: MSKFQVVEHPLIQHKLSILRRKEASTKEFRELVDEIGMLMAYEVSRDLPLEDVEIETPVQKTTVKQIAGKKLAIVPILRAGIGMVDGILKLIPAARVGHIGMYRDEETLKPVEYLVKLPADIADRQIFLVDPMLATGGSAILAVDSLKKRNSKAENIKFVCLVAAPEGVKALQEAHPDIEIYTAALDEKLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RIBB_SALPB
Sequence: MNQTLLSSFGTPFERVELALDALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRVTTVRAAIKDGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIAFAGQHNMAVVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RL15_CHITE
Sequence: MGAYRYVQELYRKKQSDVLRYLLRVRCWQYRQLTKLHRAPRPSRPDKARRLGYKAKQGFLIYRIRVRRGGRKRPVHKGCTYGKPKSHGVNQLKPYRNLQSVAEERVGRRMGGLRVLNSYWVAQDAAFKYYEVICVDPFHNAVRRDPKVNWVCNAVHKHRELRGLTSAGKSSRGVGKGYRYSQTIGGSRRAAWRRKNRLHLRRYR
What are the official names of this protein?
60S ribosomal protein L15, YL10.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: FTHS_PAEAT
Sequence: MSENKVLSDLEIAHNATMLPVEAIAERAGINVDALELYGPYKAKINTAKLVLPRGKAPGKVVLVSAMSPTPAGEGKSTTTVGLADSLARAGHKVMIALREPSLGPILGMKGGATGGGYSQVLPMDDINLHFTGDFHAITSANNALMALVDNHIFQGNQLGIDPRRMTFKRVLDMNDRALREVVIGLGGPMQGVPRQDGFDITVASEIMAVFCLATDLDDLRERLGRITFGYTYDRTPVTVSDLGVEGALTMLLKDAIKPNLVQTIAGTPALVHGGPFANIAHGCNSLIATSTAMQLADIVVTEAGFGADLGAEKYMDIKARIAEVAPSAVVVVATIRALKMQGGVPKEKLNEPNVEAVAAGVENLKRHVGNVAKFGISPVVSINKFGSDTPEELEWLLAWCAAEGVEAAVADVWGRGGGGDGGDELAAKVAAALEAPSNFHHLYPLELGVEDKIRTIVQEIYGADGVEFSVPALKRLAEIEKNGWSGLPVCMAKTQYSFTDDASRLGAPKGFRVHVRELIPKTGAGFIVALTGAVMTMPGLPKEPAAMRMDVDADGNPTGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: EX7S_SHIF8
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G6PI_SERP5
Sequence: MKNINPSQTAAWQALQQHFEQMKDVQISDLFAQDKERFSKFSATFNDQMLVDYSKNRISAETLEKLQALAKETDLQSAIKSMFAGEKINRTEDRAVLHVALRNRSNTPIIVDGKDVMPEVNAVLAKMKQFCDRVIGGDWKGYTGKAITDVVNIGIGGSDLGPYMATEALRPYKNHLNMHFVSNVDGTHIAETLQPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSTAGDQKHVAKHFAALSTNGKAVGGFGIDTANMFEFWDWVGGRYSLWSAIGLSIALSLGFDNFEQLLSGAHAMDQHFAQTPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLVPCDFIAPAISHNPLSDHHAKLLSNFFAQTEALAFGKSLEVVEAEFAAQGKTPEEVKHVAPFKVFEGNRPTNSILLREITPFSLGSLIALYEHKIFTQGAILNIFTFDQWGVELGKQLANRILPELAGDEAVSSHDSSTNALINRFKEWR
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_HAEDU
Sequence: MARIAGINIPDQKHTVIALTAIYGIGKTRAKAICVATGIAEDVKIRELSEEQIEKLREEVSKFTVEGDLRREVTLSIKRLLDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NHAP2_AERHH
Sequence: MDAVTINSFFLVAALLVGASVLLSALSSRLGIPILVIFLAVGMLAGEDGPGGIHFADYSIAYLVGNLALAIILLDGGMRTRVSSFRVALWPALSLATVGVAITTGLTGLAAAWLFDLNLMQGMLIGAIVGSTDAAAVFSLLGGRSLNERVSATLEIESGSNDPMAVFLTVTLIEVLASAQQDLNAGFLLLQLLKQFGLGAGIGLGGGWLLWKLINSAKLAPGLYPLLTVSGGLLIFALTTAVGGSGILAIYLTGLLLGNLSLRSRSTTLSVLDGLTWLSQIGMFLVLGLLASPHKLLPIALPALALAMWMILFARPISVWIGLLPFKNFAPRERWFISWVGLRGAVPIILAVFPMMAGLPNAQLYFNVAFFVVLVSLILQGSSLPLASRLARVEVPAPPSPINRSGLEIDLDSQWETFVYRLSDEKWCIGSPLRDLRMPKGTRICALFRDQELLHPSGSTCLQSDDILCVIGHERDLPALGQLFSQAPEQDLGPRFFGDFLLEAAANLVDLAPLYGLDVSEVADQTLGHFIAHQLGDNLVVGDHVEWQGLIWTVAEMDEGEPRKIGVRFLEEDPV
What is the function of this protein?
K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels.
What are the official names of this protein?
K(+)/H(+) antiporter NhaP2, Potassium/proton antiporter NhaP2.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSRB_LISMH
Sequence: MDESKKNERLQQLTDIQYNVTQKAGTERPFQNEFYDNVAKGIYVDIVSGKPLFSSNDQYDAGCGWPSFTKPIDEAEVIEHRDLTHGMIRTEVKSADADSHLGHVFPDGPQDKGGLRYCINSAALRFIPVDKLEEEGYQAYKKIFE
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: LISC2_MAIZE
Sequence: MQSSLARPPVLAGCGERRGLAAVARCRAEAAAPVWTASRASAGPYTGRDPEVKKPAWLRQRAAQGEKYARLRESIGELKLNTVCVEAQCPNIGECWNGGGGAGGEGDGIATATIMVLGDTCTRGCRFCAVKTSNKPPPPDPLEPLNTALAVASWGVDYVVLTSVDRDDLPDGGSSHFAQTVKALKELKPGILVECLTSDFRGDLEAISSLANSGLDVYAHNIETVRSLQRVVRDPRAGYDQSLAVLKHAKGSREDMITKSSIMLGLGETDEEVKQAMMDLRAIGVDILTLGQYLQPSERHLTVREYVTPQKFQFWKEYGESVGFRYVASGPLVRSSYRAGELFIQNLVRNNKTESSMDPYAEITKSN
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase 2, chloroplastic, Lipoate synthase 2, LS 2, Lip-syn 2, Lipoate synthase, plastidial 2, LIP1p 2, Lipoic acid synthase 2.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NOP58_SCLS1
Sequence: MAPLFILTETAAGLVLFKADKKLLKKDDVASEIETAEGINGLLKLKQFQKFDSAATALEEVASLVEGKVSPMLAKLLDTLKDEKKASLAVADPKLGQAINKLPGLTLTPISDSKTNDIFRGIRDHLPSLIPGLLPEHISTMSLGLSHSLSRHKLKFSPDKVDTMIVQAISLLDDLDKELNTYAMRVKEWYGWHFPEMGKIVNDNLAYARVILKVGMRVNTSSTDLADILPEEIEAAIKAAAEVSMGTEITEEDLDNIKLLAEQVVGFTEYRQQLSSYLSARMQAIAPNLTELVGELVGARLIAHAGSLMNLAKSPASTIQILGAEKALFRALKTKHDTPKYGLIYHASLVGQATGKNKGKIARMLAAKAAIGLRVDALSDWSAQGEGKGDDVDDEERSALGVTSRAKIERHLRGIEGKPLLPRGVAVGPNGKTTSAPGKWEVKEARKYNADADGLAGDEPAAAIPVREKKNKKLIEEVAEKSDSDSSDESDASEKKSKKGDKEAKKAEKAAKKAEKAAKKAAKAAKKAVKEAKEVKKSAVNDTPEVNGKKRKSEDDGEKSEKKKKKKNKD
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HNT2_YEAS2
Sequence: MNKPIYFSKFLVTEQVFYKSKYTYALVNLKPIVPGHVLIVPLRTTVLNLSDLTMPESQDYFKTLQLIHRFIKWQYKADSINVAIQDGPEAGQSVPHLHTHIIPRYKINNVGDLIYDKLDHWDGNGTLTDWQGRRDEYLGVGGRQARKNNSTSATVDGDELSQGPNVLKPDSQRKVRALTEMKKEAEDLQARLEEFVSSDPGLTQWL
What is the function of this protein?
Cleaves A-5'-PPP-5'A to yield AMP and ADP.  Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine.  Is most effective on dinucleoside triphosphates.  Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock (By similarity).
What are the official names of this protein?
Bis(5'-adenosyl)-triphosphatase, AP3A hydrolase, AP3Aase, Diadenosine 5',5'''-P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Hit family protein 2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Mitochondrion.
Protein: PURA_SHISS
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVATTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STRGG
Sequence: MSSSITTPEGIINPPIDELLEATDSKYSLVIYAAKRARQINAYYSQLGEGLLEYVGPLVDTHVHEKPLSIALREINAGLLTSEAIEGPAQ
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MRAY_BURP0
Sequence: MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVTWFKYTKRRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BOMT_BOTBR
Sequence: MALDLLSSYAPGLVESLLTWKGAAGLAAAVALGYIIISNLPGRQVAKPSLLQVRTGGVAFEKVAEVVADYSDSYGQTEKGELIVKDNNKIVSLANTFYDLITDGYEWGWGSGFHFSHRLPGMSFNASQLLHESRMASFLRLKPGMQVLDVGCGVGNPGRTVAACSGAVVTGITINAYQIKRAELHTKRAGLVGYFKPVQGNFCAMPFQDKSFDAAFAMDSTCHAPKLEDVYSEVFRVLKPGAYFATYEWVSTKNYDSNNPEHVKCMNSIILGNGLPNIRSWKQAEEAGKNVGFNLLTSLDMATNSPIGKPWYSVPERMVNWGLFRFHKACIRTASTLHLLPPESWKFFYILAEMAENLVKGGQWDIFTPMHLLIFQKPE
What is the function of this protein?
Converts botryococcene to mono- and dimethyl derivatives, but not to tri- and tetramethylated products.  Unable to methylate cycloartenol, zymosterol or lanosterol, but can also use squalene as substrate.  Methylates both C-3 and C22 positions, but only C-3 position in monomethylated squalenes.  In contrast, monomethylated botryococcene occured mainly at the C-20 position yielding showacene, but also at the C-3 position yielding isoshowacene.
What are the official names of this protein?
Botryococcene C-methyltransferase, Triterpene methyltransferase 3.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein.
Protein: PANC_BURCJ
Sequence: MKVISSIQELRDQLRGQNRTAFVPTMGNLHEGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLQDDIEKLQQENVYVLFAPTERDMYPEPQEYRVLPPDDLGGILEGEFRPGFFAGVCTVVTKLMSCVQPRVAVFGKKDYQQLMIVRRMCQQLALPVEIVAAETVRDEDGLALSSRNRYLTPDERREAPELAKTLQRVRDSVLGGERDLGKLEQHAHTHLAERGWVPDYIAIRRRANLIAPSAAELEAGEPLVVLAAAKLGATRLIDNLEI
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_CLOB8
Sequence: MKKDVLIERIEELVRPIVSELSCELYYVEYVKENGEFYLRIYIDKEGRVSLNDCEAVSRRVSEILDVEDPIKEAYYLEVSSPGLNRGLYKEEHFKKYIGSEVLIRLTSSLNGVKSVKGLLRDVSEDSILVEGETEIQIPRDKIKAANLEGEI
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THSB2_BACDA
Sequence: MPGVAKRKYVGETMRINKNLSQVLRRLSDVLPYNYNAETLLELFQQLYPHEWRELNQRFDQYKEKDEFLLKKGKKIRYKPNPPKEHFFKLPIVKNILSKGRIAKHNANFDELAYQERFAKFKAKRENAIRSRNEKIAKANELIQNVEPLFIDTFIAAYHKRGISFDEKMEIFKELQKYKSKKTAEFFYKLSESERNNQIRNMAFKHLQVTGNYVKLRKNFNGKKKEYMTESSEFFMTPLDLLKRIESNNVQNKKVYDVFISHSYKDSSVIKKIIKAFNKLSISIYCDWTSDSDFLKRELVSEYTKVVLKKRIEQSKNIVFVKTDNSLESHWVRFELDYSRELGKTLFCINLSDEAEGECNVLQFDVKNETISWTTGLVK
What is the function of this protein?
One of 2 TIR-like protein components of the Thoeris antiviral defense system, composed of ThsA, TIR1 (thsB1) and TIR2 (thsB2).  Phage infection activates this protein; by 70 minutes post-infection with phage SPO1, TIR2 generates a signal molecule that in turn activates the NAD(+) hydrolase activity of ThsA (tested with B. cereus).  The signal is similar to cyclic ADP-D-ribose, but how it differs is unknown.  Expression of Thoeris in B. subtilis (strain BEST7003) confers resistance to phages phi29, phi3T, SPBeta, SBSphi11, SBSphi13, SBSphiJ, SPO1 and SPR but not SBSphiC.  The TIR paralogs confer resistance to different phages; this subunit confers resistance to phi3T, SPBeta, SBSphi13, SBSphiJ, SPO1 and SPR but not phi29, SBSphi11 or SBSphiC.  There is overlap in the phage range for this system, both TIR1 and TIR2 are activated by SBSphi13, SBSphiJ, SPO1 and SPR.  Probably hydrolyzes NAD(+) to make a cyclic ADP-D-ribose (cADPR) signaling molecule; might make 3'cADPR (By similarity).
What are the official names of this protein?
Putative cyclic ADP-D-ribose synthase TIR2, Putative cADPR synthase TIR2, Thoeris protein TIR2.
What are the subcellular locations of this protein?
Cytoplasm.