PharMolix/UniProtQA huggingface dataset:
Protein: TSAE_RICPR
Sequence: MHTLNSKKETKNFAKLFAQNLKPNDIVLLNGDLGAGKTFFCREIIKHFCGKNTNIISPTFNLLQIYKTPKFNIYHYDMYRIKSPEEIYELGFEEALNGNLILIEWSEIIKHLLTPPLIEVNLKVLDNNKRLCSIHKENFLFDFL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB.  TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity).
What are the official names of this protein?
tRNA threonylcarbamoyladenosine biosynthesis protein TsaE, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE.
What is the protein family that this protein belongs to?
Belongs to the TsaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIB45_LACPN
Sequence: XAPQNXMNGL
What is the function of this protein?
Bacteriocin with a broad antibacterial spectrum against various Gram positive, Gram negative food borne and multidrug resistant pathogens, and against some fungal pathogenic strains (Ref. 1, Ref. 2).  Displays bacteriocidal activity against L. monocytogenes ATCC 7644 (MIC=80 ug/ml), and inhibits the growth of M. luteus KIBGE-IB20 (MIC=160 ug/ml), P. aeruginosa ATCC 27,853 (MIC=80 ug/ml), S. aureus KIBGE-IB23 (MIC=160 ug/ml), B. cereus ATCC 11,778 (MIC=80 ug/ml), E. coli ATCC 8739 (MIC=80 ug/ml), E. faecalis ATCC 29,212 (MIC=40 ug/ml), A. terreus KIBGE-IB-35 (MIC=40 ug/ml) and A. flavus KIBGE-IB34 (MIC=20 ug/ml) (Ref. 2).  Has no activity against B. licheniformis KIBGE-IB3, A. niger KIBGE-IB-36 and A. fumigatus KIBGE-IB33 (Ref. 2).
What are the official names of this protein?
Bacteriocin IB45, Bac-IB45.
Protein: GLGC_BACCN
Sequence: MVKKQNCVAMLLAGGKGSRLSALTKNLAKPAVPFGGKYRIIDFTLSNCSNSGIETVGILTQYQPLELHNYIGIGNAWDLDRVNGGVTVLPPYAEASGVKWYTGTASAIYQNMNFLRQYNPEYVLILSGDHIYKMDYSKMLDYHIAKEADVSISVIEVPWDEASRFGIMNTNEEMEIVEFEEKPQFPKSNLASMGIYIFNWAILKEYLEMDARNPDSSNDFGKDVLPLLLDEGKKLIAYPFQGYWKDVGTVKSLWEANMDLLRDESLLQLNDHEWRVYSVNPNEPPQFISETAKVEESLINEGCIIEGEVRHSVLFQGVTVDEGSKVIDSVVMPGAHIGKNVVIEKAIVGPGMVIEDGEVIRSEKNTDDVVLIAEGI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: ATPE_RICTY
Sequence: MNETIQVKIITPSSIAFEKQSKMVTMPGEDGMFGVLPNHVPMIVNLTAGLVQVYINNMHNSENTYLISGGVTEITSNYINIVTEAAINVTNLSESEISTQCYELQKLSSH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LDRC_ECOLI
Sequence: MTLAQFAMIFWHDLAAPILAGIITAAIVSWWRNRK
What is the function of this protein?
Toxic component of a type I toxin-antitoxin (TA) system.  Overexpression causes rapid cell killing, probably by disrupting the cell inner membrane and disruption of ATP synthesis.
What are the official names of this protein?
Small toxic polypeptide LdrC.
What is the protein family that this protein belongs to?
Belongs to the Ldr toxic peptide family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MANEL_HUMAN
Sequence: MARRRRRACIALFLVLLFAFGTLMGLRTLKAPDGLPALGPGLELAPFERRPEGAPAPAARAPAAPAAPPPPPPPPRTADPGGSPGPAPAEAEPAPVQSLRVYSDLHAFYYSWYGSPRREGHYIHWDHVMVPHWDPKISASYPRGRHSPPDDLGSSFYPELGPYSSRDPEVLREHMTQLKEAAIGVLVLSWYPPGMADDNGEPSDDLVPAILDTAHQYSIQVAFHIQPYKGRDDITVHDNIKYIIDTYGSHGAFYRYKNSMGKSLPLFYIYDSYLTSPEAWAHLLTPNGPHSIRNTPYDGVFIALLVEEGHTHDILAAGFDGMYTYFASNGFSFGSSHQNWKAVKNFCDANNLMFIPSVGPGYIDTSIRPWNNHNTRNRVNGKYYETALQAALTVRPEIVSITSFNEWHEGTQIEKAIPKKTPTRLYLDYLPHQPSLYLELTRRWAEHFIKEKEQWLM
What are the official names of this protein?
Glycoprotein endo-alpha-1,2-mannosidase-like protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 99 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RS13_KOCRD
Sequence: MARLAGVDLPREKRLEVALTYIYGVGRTRALETLEATGISGDVRVKDLTDPQLVELRDYIEGNYKVEGDLRREVAADIRRKVEIGSYQGLRHRRGLPVHGQRTKTNARTRKGPKRTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: STA5A_PIG
Sequence: MAGWIQAQQLQGDALRQMQVLYGQHFPIEVRHYLAQWIESQPWDAIDVDNPQDRAQATQLLENLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSSAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLNPQECLSRETALQQKQVTLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNESTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSSHLEDYSGMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRLGDLSYLIYVFPDRPKDEVFSKYYTPVLAPASAAKAVDGYVKPQIKQVVPEFVSASSDSAGGNATYMDQAPSPAVCPQAHYSIYPQNPDPVLDQDGEFDLDETMDVARHVEELLRRPMDSLDPRLSPPAGLFASTRGSLS
What is the function of this protein?
Carries out a dual function: signal transduction and activation of transcription.  Mediates cellular responses to the cytokine KITLG/SCF and other growth factors.  May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4.  Binds to the GAS element and activates PRL-induced transcription.  Regulates the expression of milk proteins during lactation (By similarity).
What are the official names of this protein?
Signal transducer and activator of transcription 5A.
What is the protein family that this protein belongs to?
Belongs to the transcription factor STAT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation.
Protein: RL4_SHISS
Sequence: MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTRAQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYRGALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLAARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PHYB_ASPAW
Sequence: MPRTSLLTLACALATGASAFSYGAAIPQSTQEKQFSQEFRDGYSILKHYGGNGPYSERVSYGIARDPPTSCEVDQVIMVKRHGERYPSPSAGKDIEEALAKVYSINTTEYKGDLAFLNDWTYYVPNECYYNAETTSGPYAGLLDAYNHGNDYKARYGHLWNGETVVPFFSSGYGRVIETARKFGEGFFGYNYSTNAALNIISESEVMGADSLTPTCDTDNDQTTCDNLTYQLPQFKVAAARLNSQNPGMNLTASDVYNLMVMASFELNARPFSNWINAFTQDEWVSFGYVEDLNYYYCAGPGDKNMAAVGAVYANASLTLLNQGPKEAGSLFFNFAHDTNITPILAALGVLIPNEDLPLDRVAFGNPYSIGNIVPMGGHLTIERLSCQATALSDEGTYVRLVLNEAVLPFNDCTSGPGYSCPLANYTSILNKNLPDYTTTCNVSASYPQYLSFWWNYNTTTELNYRSSPIACQEGDAMD
What is the function of this protein?
Catalyzes the hydrolysis of inorganic orthophosphate from phytate.
What are the official names of this protein?
3-phytase B, Myo-inositol-hexaphosphate 3-phosphohydrolase B, pH 2.5 optimum acid phosphatase.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
Protein: RBSC_ECOLI
Sequence: MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTINNLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVAAALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADLFGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNKIKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIVGTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ
What is the function of this protein?
(Microbial infection) Probably transports the toxic C-terminal region of CdiA from D. dadantii strain 3937 across the inner membrane to the cytoplasm, where CdiA has a toxic effect.  Toxin transport is strain-specific, mutations in this gene do not confer resistance to several other tested CdiA toxins.
What are the official names of this protein?
Ribose import permease protein RbsC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. AraH/RbsC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TKT_GEOSE
Sequence: MAHSIEELAITTIRTLSIDAIEKAKSGHPGMPMGAAPMAYTLWTKFMNHNPANPNWFNRDRFVLSAGHGSMLLYSLLHLSGYDVSMDDLKQFRQWGSKTPGHPEYGHTPGVEATTGPLGQGIAMAVGMAMAERHLAATYNRDGFEIINHYTYAICGDGDLMEGVASEAASLAGHLKLGRLIVLYDSNDISLDGELNLSFSENVAQRFQAYGWQYLRVEDGNNIEEIAKALEEARADLSRPTLIEVKTTIGYGAPNKAGTSGVHGAPLGAQEAKLTKEAYRWTFAEDFYVPEEVYAHFRATVQEPGAKKEAKWNEQLAAYEQAHPELAAQLKRAIEGKLPDGWEASLPVYEAGKSLATRSSSGEVINAIAKAVPQLFGGSADLASSNKTLIKGGGNFLPDSYEGRNVWFGVREFAMGAALNGMALHGGLKVFGGTFFVFSDYLRPAIRLAALMGLPVIYVLTHDSIAVGEDGPTHEPIEHLASLRAMPNLSVIRPADANETAAAWRLALESTDKPTALVLTRQDVPTLAATAELAYEGVKKGAYVVSPAKNGAPEALLLATGSEVGLAVKAQEALAAEGIHVSVISMPSWDRFEAQPKSYRDEVLPPAVTKRLAIEMGASLGWERYVGAEGDILAIDRFGASAPGEKIMAEYGFTVDNVVRRTKALLGK
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, likely via a covalent intermediate with the cofactor thiamine pyrophosphate.  Can use L-erythrulose as donor and D-ribose-5-phosphate as acceptor substrates, forming glycolaldehyde and D-sedoheptulose-7-phosphate.  For synthetic purposes, is able to use hydroxypyruvate (HPA) as donor substrate, making the reaction irreversible due to the release of carbon dioxide, and various aldehydes as acceptor substrates, which leads to the corresponding ketoses.  Thus, using hydroxypyruvate as donor and three different aldehydes as acceptors, i. e.  glycolaldehyde, D-glyceraldehyde and butyraldehyde, the enzyme stereoselectively forms the corresponding products L-erythrulose, D-xylulose and (3S)-1,3-dihydroxyhexan-2-one, respectively.
What are the official names of this protein?
Transketolase, TK.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: RS7_XANOM
Sequence: MSRKGSTPQRTVLPDPKHGSETIARFINMVMQSGKKSVAEKIVYGAMDVIGEKNPNAIELVQKALDNVAPAVEVKSRRVGGATYQVPVEVRSSRRMALAMRWLIDSARKRGENTMPRKLAAELLDAAESRGGAIKKREETHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: TMEDA_NEUCR
Sequence: MASLKSLLSGFLLLAGAAQALKFDLEATSSHHSNQRRCIRNFVNKDTLVVVTATLDGYKGDGMNVNMHISDSHGNEYGKAKDIAGEQRIVFTSHHDAAFDVCFENYLTGSKYVENPRRHVELDIDIGADAKDWSAIQATEKLKPLETDLRRIEELVGEVVNEMDYLRAREQKLRDTNESTNNRVKWFGMATTFLLIALWGWQIMYLRAYFRSKHLI
What is the function of this protein?
Constituent of COPII-coated endoplasmic reticulum-derived transport vesicles.  Required for efficient transport of a subset of secretory proteins to the Golgi.  Facilitates retrograde transport from the Golgi to the endoplasmic reticulum (By similarity).
What are the official names of this protein?
Endoplasmic reticulum vesicle protein 25.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Note=Recycles between endoplasmic reticulum and Golgi.
Protein: HIS1_YERP3
Sequence: MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_POLNS
Sequence: MSISDPIADMLTRIRNAQAVQKPLVTMPSSKVKVAIAKVLQDEGYIENFEIKGEAAKPVLHIDLKYYAGHPVIERIDRVSTPSLRIYKGRHDIPEVMNGLGIAIISTPQGVMTDRKARATGVGGEVICYVA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: FLOR1_ARATH
Sequence: MKLFVHLSIFFSILFITLPSSYSCTENDKNALLQIKKALGNPPLLSSWNPRTDCCTGWTGVECTNRRVTGLSVTSGEVSGQISYQIGDLVDLRTLDFSYLPHLTGNIPRTITKLKNLNTLYLKHTSLSGPIPDYISELKSLTFLDLSFNQFTGPIPGSLSQMPKLEAIQINDNKLTGSIPNSFGSFVGNVPNLYLSNNKLSGKIPESLSKYDFNAVDLSGNGFEGDAFMFFGRNKTTVRVDLSRNMFNFDLVKVKFARSIVSLDLSQNHIYGKIPPALTKLHLEHFNVSDNHLCGKIPSGGLLQTFEPSAFAHNICLCGTPLKAC
What is the function of this protein?
Promotes flowering transition in long days (LD).
What are the official names of this protein?
Leucine-rich repeat protein FLOR 1, Protein FLORAL TRANSITION AT THE MERISTEM 4.
What is the protein family that this protein belongs to?
Belongs to the polygalacturonase-inhibiting protein family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Cell membrane. Note=In carpels, observed both in cytoplasm and nucleus, as well as in the perinuclear and cell membrane in a vesicle-like pattern. In style cells, present in cytoplasm as well as in nucleus possibly in the perinuclear membrane. In leaf tissue, observed in the plasma membrane and in the perinuclear membrane. In roots and tapetum cells, restricted to the cytoplasm.
Protein: MESD_CHICK
Sequence: MAAAARWAALGLALWLCAAAHAEEPEGKRRAGPAKKKDIRDYNDADMARLLEQWEKDDDIEEGDLPEHKRPPAPIDFSKIDPGKPESILKLTKKGKTLMMFVTVSGNPTEKETEEITSLWQGSLFNANYDVQRFIVGSNRAIFMLRDGGYAWEIKDFLISQERCADVTLEGQVYPGKGADGSEKGRNKTKPEKAKKKKDAEKSKSSHEDNRAQTKQREDL
What is the function of this protein?
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs).  Acts as a modulator of the Wnt pathway, since some LDLRs are coreceptors for the canonical Wnt pathway (By similarity).
What are the official names of this protein?
LRP chaperone MESD, LDLR chaperone MESD, Mesoderm development candidate 2, Mesoderm development protein.
What is the protein family that this protein belongs to?
Belongs to the MESD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: KHSE_SYNWW
Sequence: MFTVKVPATSANLGPGFDTLGLALQLYLELKVTIIPQSTRIRFFVDGEEYPEEIFGDNLVYQAMKKVFAEAAVVEAPGLELTINSSIPPGKGLGSSAAAIVAGLYAANEILEKRFTQEDLISWAVEMEGHADNVVPAVAGGLTTAMLYRGNVYYQQFTFPPELKLVVAVPDIQISTDESRQLLPKKIDFMDMVNNLQRASYLLASLIKHDFRYLPAAMDDVIFQPRRKQLIPGFDRVFSQALGNGAVGVALSGSGSSIIAFCQQEEKRVAEAMQDAFAASGIQSQLMILAADPDGVKVLR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_SALTI
Sequence: MIEFVYPHTHLVAGVDEVGRGPLVGAVVTAAVILDPARPIVGLNDSKKLSEKRRLSLYDEIKEKALSWSLGRAEAHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPELPVPSMAVVKGDSRVAEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAQYGATAHHRRSFAPVKRALGLVS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMJ_KLEP3
Sequence: MKICLIDETGAGDGALSVLAARWGLEQDEDNLMALVLTTEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLAPARQLATKRVVVKRPDYAPPLAEVATPNAVVTKGHRFDIYAGTPE
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPP2_BOTFB
Sequence: MSSFTAQDKDQEVRPSSSGSWACKEVDEFDALSIEYKPKPTEKYPAKLHARNVRKYLDVGEGLIYLPGLPSFNYEDSDMPPAFRQRRYFYYITGVNLSDCIVTYNIHRDQLWLWIPPPNSGRSVIYNGARPTIKEIMSKYDFDHVETLTHLDSYLTWYAHTEPGKIHVLHDYQAPKNIELQITRKNGCHSIISESPFDSSKLEEAMNTARAIKSPYELRMIRKASAITAQGHLNVLRGLRHLSNEAEIEAIFTATCIAKQAKTQAYGVIAGSGENASTLHYMANNEPLKGRQLLCLDAGCEWDCYASDVTRTVPISGEYTEEAEAIYDIVAKMQDECIELLKPGANYRDIHIHAHKVALKGLMDLGLVEGGTFDELFMAGVSVAFFPHGLGHYVGLEVHDVGPGGSRITNRLYGFDKKPADWTDAYFQILSNTGVTSDGGSILEKDMVVTVEPGIYFSRYALEEVYLKSPNYAKYINKDLLQKYYPVGGVRIEDDLLITEDGYENLTTVLKGKEALKIINEGKEQEEEEEREANRKATESRKQKKTWFW
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase BC1G_13431, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: PNP_SHEON
Sequence: MNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKEAEAGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSEEETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPEIEPDIISMIGTSAALAISGIPFNGPLGAARVGYINGEYVLNPTVKQIGASQLNLVVAGTESAVLMVESEAQALPEEVMLGSVVYGHDQQQVVIKAIAEFKAEAGKPTWDWTAPVEDEALVAQIKELAEAGFIEAYQIQVKQERYAQVAVVKAAAKEALLAANPDVDLREVDNLLGSLEKKVVRGRILRGMPRIDGREPDMVRALSVLAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKIDSIMGERTNRFMLHYNFPPYSVGETGMVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGVTALQMDIKIEGITKEIMEIALQQAYGARVHILNVMDQAIGSHRADISDHAPRITTIKINPEKIRDVIGKGGAVIRALTEETGTTIELEDDGTVKIASSNGEATKEAIRRIEEITSEVEVGRIYNGKVIRIVDFGAFVNILPGKDGLVHISQISDERVANVSDHLELNQEVTVKVMEVDRQGRVRLSIKEAQTKEPAAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSC_SHIDS
Sequence: MKRIAFVFSTVPHGTAAGREGLDALLATSALTDELAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMBR_RAT
Sequence: MPPRSLPNLSLPTEASESELEPEVWENDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLTNSTMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVVLWTSLKAVGIWVVSVLLAVPEAVFSEVARIGSSDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIRSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHILYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCCGQKSYPERSTSYLLSSSAVRMTSLKSNAKNVVTNSVLLNGHSTKQEIAL
What is the function of this protein?
Receptor for neuromedin-B (PubMed:1848080).  Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (PubMed:26855425).  Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem (By similarity).  These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response (By similarity).  Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide (By similarity).  Plays a role in the innate immune response to influenza A virus infection by enhancing interferon alpha expression and reducing expression of IL6 (By similarity).  Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (By similarity).
What are the official names of this protein?
Neuromedin-B receptor, NMB-R, Neuromedin-B-preferring bombesin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRP1_YEASO
Sequence: MSSELMFNYTFSWPAGPKDVILTGTFDDWRGTLPLVKTAKGNFEITMPVKLANKDDTFQFKFIVDGVWCVSDSYKKEHVSEGIENNFLQITDLVETQEVAGASRIPEAGGLLCGKPPRSAGPPSTSNRKKNKRNNKKRRSKLKKKSTKNNKKSNESLDDNEEEDGVTGTTTEDVTGTSREETPLAEPTNVSKEAPGNFHILPIDQSADTTQSNGIIGGPGPVLVPNPGEIKEFTEIRDVDARELNERLNKKEEVPEPVAGPIVESSVTEKSPALPQADDLIVETKEMAHNVQELTPQVEAVTPLINEPEPLPTPEAQISIPESSKVEPVEGSLQPKLVEKRESTEGVSDGSKKVENKAKKDEEVFTLDPIVNKAPKLPLTDEQTAEGRKSPAVSEEKEKKKKQEKGSKEVKRSETSKEKKPSAKEVKKQTVKAPKKQTASPLSSSTEEPKKKKTGFFGKLKKLFK
What is the function of this protein?
Cruciform DNA-binding protein which exerts an enhancing effect on the cleavage of cruciform DNA (X-DNA) by endonuclease VII from bacteriophage T4.
What are the official names of this protein?
Cruciform DNA-recognizing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CRP1/MDG1 family.