PharMolix/UniProtQA huggingface dataset:
Protein: LEPA_CORDI
Sequence: MAEKFAEKTFTDPQQIRNFCIIAHIDHGKSTLADRILQLSNVVDARDMRDQYLDNMDIERERGITIKAQNVRLPWIPRTGPYAGEQIVMQMIDTPGHVDFTYEVSRALEACEGAILLVDAAQGIEAQTLANLYLAMENDLEIIPVLNKIDLPAADPEKYSLEIANIIGCEPEDVLRVSGKTGEGVEELLDKVAELIPAPTTDYPDDAPARAMIFDSVYDTYRGVVTYIRMIDGKLTPRQKIKMMSTGAVHELLEIGIVSPTPKKCSGLGPGEVGYLITGVKDVRQSKVGDTVTWAHNGAEEALQGYEEPKPMVYSGLFPISQADFPDLRDALEKLQLNDASLTYEPETSVALGFGFRCGFLGLLHMEITRDRLQREFDLDLISTAPSVNYRVVAEDGSEHRVHNPSDWPAGKLREVYEPIVKTTIIVPSDFVGTTMELCQTKRGQMDGMDYLSEDRVELRYTMPLGEIIFDFFDQLKSRTKGYASLNYEEAGEQLADLVKVDILLQGDPVDAFSAIVHRDNAQWYGNKMTKKLKELIPRQQFEVPVQAAIGSKVIARENIRALRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKNIGSVSVPQEAFVAALSTDEG
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RD44_PHYIT
Sequence: MRLLLWVLISMLSIALSSCAAASADSNERLVRAVYSTVRSRDLATDDGPKHTKRFLRGESSKIVNLKQEEGVFEERKGVSQKLTKALQAIKARYLKWEQKVLVPGFKKMAEKGVTYSELRDTFRVRMMNSGRWGTPSGFKRYARLYSEWLHRTGRSHLAK
What is the function of this protein?
Effector that is involved in host plant infection.  Contributes to virulence during the early infection stage, by inhibiting plant defense responses induced by both PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI).
What are the official names of this protein?
RxLR effector protein PexRD44, Core RXLR effector 14.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane. Host nucleus, host nucleolus.
Protein: IF3_RICPR
Sequence: MYLFINIIWRNFISKNNLPKANREIKAKEVRLVDENSEMYGVVNIREALDMAERAGLDLVEISPNAVPPVCKILDFGKFKYESKKRLHEARKKQKVVVLKEMKFKPNISIGDFETKLRKIKEFLKDGDKVKISLWFKGREILHKEVGHELFKRIELALEGLIKIDQHAKMEGKQMIMIVSPDIKV
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSP1_OSTOS
Sequence: MKYLFFALCLYLYQGISEAEVPAEQIPLEAQALSGLPLVEYLQKNQRLFEVTATPVPYFKQRLMDLKYIDQNNIPDEEVEDEELEENNDDIPESYDPRIQWANCSSLFHIPDQANCGSCWAVSSAAAMSDRICIASKGAKQVLISAQDVVSCCTWCGDGCEGGWPISAFRFHADEGVVTGGDYNTKGSCRPYEIHPCGHHGNETYYGECVGMADTPRCKRRCLLGYPKSYPSDRYYKKAYQLKNSVKAIQKDIMKNGPVVATYTVYEDFAHYRSGIYKHKAGRKTGLHAVKVIGWGEEKGTPYWIVANSWHDDWGENGFFRMHRGSNDCGFEERMAAGSVQ
What is the function of this protein?
Expression of the protease correlates with blood-feeding and suggests a role for the protease in blood digestion.
What are the official names of this protein?
Cathepsin B-like cysteine proteinase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: GID1_ORYSJ
Sequence: MAGSDEVNRNECKTVVPLHTWVLISNFKLSYNILRRADGTFERDLGEYLDRRVPANARPLEGVSSFDHIIDQSVGLEVRIYRAAAEGDAEEGAAAVTRPILEFLTDAPAAEPFPVIIFFHGGSFVHSSASSTIYDSLCRRFVKLSKGVVVSVNYRRAPEHRYPCAYDDGWTALKWVMSQPFMRSGGDAQARVFLSGDSSGGNIAHHVAVRAADEGVKVCGNILLNAMFGGTERTESERRLDGKYFVTLQDRDWYWKAYLPEDADRDHPACNPFGPNGRRLGGLPFAKSLIIVSGLDLTCDRQLAYADALREDGHHVKVVQCENATVGFYLLPNTVHYHEVMEEISDFLNANLYY
What is the function of this protein?
Functions as soluble gibberellin (GA) receptor.  GA is an essential hormone that regulates growth and development in plants.  Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs.  Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling.  This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway.
What are the official names of this protein?
Gibberellin receptor GID1, Gibberellin-insensitive dwarf protein 1, Protein GIBBERELLIN INSENSITIVE DWARF1.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RM52_HUMAN
Sequence: MAALGTVLFTGVRRLHCSVAAWAGGQWRLQQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAERETFARRVVLLSQEMDAGLQAWQLRQQKLQEEQRKQENALKPKGASLKSPLPSQ
What are the official names of this protein?
39S ribosomal protein L52, mitochondrial, L52mt, MRP-L52, Mitochondrial large ribosomal subunit protein mL52.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL52 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ERA_CLOBM
Sequence: MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTPGIHKPKHKLGEYMVKSASDAMKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLNKIDENPQEKVAETLKTYSELMEFEEIIPISALKGKNIDLLKELMFKYIPEGPQYYPEDMIIDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKRNEKGTYHIEGNILCEKNSHKPIIIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKNMK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: RPOB_ROSDO
Sequence: MAQSFLGQKRLRKYYGKIREVLDMPNLIEVQKSSYDLFLNSGEAEVPTDGEGIAGVFQSVFPIKDFNETSVLEYVKYELEKPKYDVEECQQRDMTYSAPLKVTLRLIVFDVDEDTGAKSVKDIKEQDVFMGDMPLMTPNGTFVVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFACRIIPYRGSWLDFEFDAKDIVFARIDRRRKLPVTTLLYSLGLDQEAIMDAYYDTITYKLEKNKGWVAPFFPDRVRGTRPTYDLVDAASGEVLFERGKKVTPRAVKKLIDEGKVTELLLPYEHIAGKFVAKDIINEETGAIYVEAGDELTLEYDKDGTLIGGTAKELVDAGITEIPVLDIDNVNVGPYMRNTMAQDKNMNRDTALMDIYRVMRPGEPPTVEAASALFDTLFFDAERYDLSAVGRVKMNMRLALDAEDTQRTLRREDIVACIKALVDLRDGRGDIDDIDHLGNRRVRSVGELMENQYRVGLLRMERAIKERMSSVEIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRMCPIETPEGPNIGLINSLATFARVNKYGFIETPYRKVENRMVTDEVQYMSATEEMRHTVAQANAQLDEDGRFKNDLVSTRQSGDYTLAPSENVDLIDVSPKQLVSVAASLIPFLENDDANRALMGSNMQRQAVPLLQAEAPLVGTGIEEVVARDSGAAIMAKRAGIIDQVDAQRIVIRATSDLELGDAGVDIYRMRKFQRSNQNTCINQRPLVKVGDTVLKGQVIADGPSTDMGELALGKNVVVAFMPWNGYNYEDSILISERIARDDVFTSIHIEEFEVAARDTKLGPEEITRDIPNVGEEALRNLDEAGIVYIGADVEPGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVKPGDFGTVVEVRVFNRHGVEKDERALQIEREEVERLARDRDDEMAILDRNIYARLKSTILGKVAVKGPKGVSANAEITEDLLQMLPRVQWWQLALKDEGDAQVVEALNEQYEIQKRTLDARFEDKVEKVRRGDDLPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISKVVPMEDMPFLADGTPVDFCLNPLGVPSRMNVGQILETHMGWAARGLGLNVDEALQEYRRSGDLTPVRDALSHAYGENVYDEGIAGMDEETLIEAAGNVTRGVPIATPVFDGAKEGDVNDALVRAGFSESGQSILFDGRTGEQFARPVTVGVKYLLKLHHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVKGEDNFEAGVPESFNVLVKEVRGLGLNMELLDAEEDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RS10_MESH2
Sequence: MNTTSIKIKLKSFDHRQIDAAAKKIILLARELNIETRGPVPLPTSRAIYTILRSVHINKKSREQFESRTHKRLVILKVLPTNQKLVTEKISRSQLPAGVWIEIEVS
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SURE_HERAR
Sequence: MKILISNDDGYLAPGLIALADALAPIADIVVVAPDSNRSGSSNSLTLDRPLSVYQASNGFYFINGTPSDCVHIALTGIMSFRPDLIVSGINQGQNMGDDTLYSGTVAAATEGHLFGIPAIAFSQLEKGWAELKSAARVARDIVERRFETLPENFLLNVNIPNLPYEQLKPAVATRLGRRHQSEAVIKAQDPHGRDIYWIGPSGGQKDAGEGTDFHATAQGHVSITPLQIDLTQNAQLAALKKVLA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE3_MYCGI
Sequence: MRLTPHEQERLLLSYAAELARRRQARGLKLNHPEAVAIITDHILEGARDGRTVAELMISGRDVLGRDDVLVGVPEMLDDVQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_ENTFA
Sequence: MKQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVAAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLPAELWKESGRYETYGPNLYRLKDRNDRDYILGPTHEETFTELIRDEINSYKRLPLNLYQIQTKYRDEKRSRSGLLRGREFIMKDGYSFHADEASLDQSYRDYEKAYSRIFERCGLEFRAIIGDGGAMGGKDSKEFMAISEIGEDTICYSTESDYAANLEMATSLYTPKKSHETQLDLEKIATPEVGTIAEVANFFEVEPQRIIKSVLFIADEEPVMVLVRGDHDVNDVKLKNFLGADFLDEATEEDARRVLGAGFGSIGPVNVSEDVKIYADLAVQDLANAIVGANEDGYHLTNVNPDRDFQPISYEDLRFVQEGDPSPDGNGVLAFTKGIEIGHIFKLGTRYSDAMGATVLDENGREKSVIMGCYGIGVSRLLSAIVEQNADERGINWPTGIAPFDLHVVQMNVKDEYQTKLSQEVEAMMTEAGYEVLVDDRNERAGVKFADADLIGCPIRITVGKKAVDGVVEVKIKRTGEMLEVRKEELESTLSILMNTTSEVE
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARS_LAVAN
Sequence: MAAPISTNNVCSDDARPVTYHPNVWSDYFLRYTSELTEISVAKKEEHERQKEAIRNLLLQTRDDSTLKLELVDAIQRLGIGYHFEEEIHNSLRNIYDTNPIYNAEDDNLRVAALRFRLIRQQGFPAPCDVFRKFVDEEGEFKSWVSNDVEGLLNLYEASNFAVHGEEILEKALEFCSLRLEFLTQGMTNSLSMRVKEALKIPISKTLTRLGARKFMSMYQEDESHNETLLNFAKLDFNLVQKIHQKELNQITRWWKELDFGKNLPFARDRPVECYFWIVGVYFEPRYGIARTLLTKIIYLASVLDDIYDVYGTLAELTIFTQIIRRWDSDAMDQLPPYMRIYCKALFDVYVEMEEEMGKIRKSYAVEYAKKEMKRLAEMYFQEAQWAFSKYKPTMKEYLKVALISSGYMMMTINSLTTIEDLITEEEFNWILSEPRILRASLTITRLMDDLAGYGTEGKMSAVHYYMAENGVSEGEAFKEVSGIIKSAWKDVNAECVEPRAASTTILRCVVDFTRVIVLLYSDEDAYGNSQTKTKDLIKSVLVDPLII
What is the function of this protein?
Sesquiterpene synthase that catalyzes the formation of sesquiterpenes and sesquiterpenoid alcohols (PubMed:24078339).  Converts farnesyl diphosphate (FPP) to beta-caryophyllene (PubMed:24078339).  Can use geranyl diphosphate (GPP) to produce myrcene, limonene and camphene (PubMed:24078339).
What are the official names of this protein?
Beta-caryophyllene synthase, LaCARS, (-)-beta-caryophyllene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: ZORA_ECO24
Sequence: MSWLNSVLLALTSVQPYMVPATVIGLVSFAFLCFIFFYFFRAVKIINGLKKYTQSINGIENNEPGNQLQHLQSLFVQPELKHAWNEFEESLHSQYELEDGEEKIVRIRATAPSASFFSEQQLVDIPLNTEFFKHLPGILTGVGIIGTFYGLMIGLNHFDPSTPEQVSSSVNNLLRDVLYAFLGSAFAITFSILITWLEKFCLAKCYKYLEKFTAALDALYDSGVGEEYLASLVKSSNESATQARHLKESLVTDLRDMLLHLANSQKVENERLATTLSTTYRETGQQFAEQVSGAIENSLKSPLDKIAGAVQTASGDQSGMVQNMLQDVLTAFMAKLDTTFGQQFTNLNEMMGQTVGAIQTMQTGFGALLQDMRQVSDDSRQGSAQLIEQLLSEMKSGQQAMQAGMNDMLTSLQTSVAKIGAEGEGAGERMARQLEKMFADSEAREKAQAEHMTAFIEAIQNSVQQGQSATMEKMAASVESLGEQLGSLFGQIDKGQQQISANQQANQQSLHEQTQRVMSEVDDQIKQLVETVASQHQGTTETLRLLAEQTNRQIQDMHTGADKMRLAAERFEHAGDRVSEANHLTADVLNKAQSAGSSLSLATSELTSVVADYRNNREAVSKSIAMLELLAANTQSEQTTRTQFIADLKQHGERLQSYNREAQAFMENVSDVLGKGFEDFSEGVSRSLDKTLGKLDVEMAKASTLLAGSVEQIGESVSELDDVLSRVRA
What is the function of this protein?
Component of antiviral defense system Zorya type I, composed of ZorA, ZorB, ZorC and ZorD.  Expression of Zorya type I in E. coli (strain MG1655) confers 10,000-fold resistance to phage SECphi27, 100-fold resistance to lambda, and 10-fold resistance to T7.  While most T7 infected Zorya-containing cells undergo abortive infection, a minority produce viable phage progeny.  These eventually accumulate to a high multiplicity of infection, leading to culture collapse by 2 hours after initial infection (PubMed:29371424).  ZorA and ZorB probably assemble in the cell inner membrane and exert their effect there (Probable).
What are the official names of this protein?
Zorya protein ZorA.
What is the protein family that this protein belongs to?
Belongs to the MotA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS15_BUCAT
Sequence: MSLSAIDTKKIILKYGKSEQNSGITEVQVVLLTNQINYLQIHFSQHKKDHCSRRGLLNMVSKRRKLLDYLKKKNISRYSALIEDLHLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: SECA_THIDA
Sequence: MLQSLFKKVFGSRNERLVKQYLQKVKAINALEPAMEQLSDAELAGKTADFKARIEQGTSLDTLLPEAFAVVREAARRVLGLRHYDVQMVGGMVLHDGKIAEMRTGEGKTLMATLPAYLNALAGKGVHVVTVNDYLARRDAEWMGRVYGFLGLTTGVNLSHMPHAEKQAAYAADITYGTNNEYGFDYLRDNMVFEVGEKVQRPLAFGVIDEVDSILIDEARTPLIISGQSEENTALYQQVNLVPPRLTRQKDEESEGDYSVDEKSRQVLLSEAGHEKVEEILTEMGLLQPGGSLYDASNIMLMHHVYAALRAHALFFKDQHYVVQNGEVVIVDEFTGRLMSGRRWSEGLHQAVEAKEGVAIQKENQTLASITFQNFFRMYEKLSGMTGTADTEAFEFQSIYGLETVVIPTHRPMIRKDEHDQVYRTGRERDQAVINDVRACHERGQPVLVGTTSIEANEKLSAELKKAGLPHNVLNAKQHASEAEVIAQAGLPGAVTIATNMAGRGTDIVLGGSIQKEVDAIRNDAALADGEKDARITALKADWQTRHDAVLAAGGLHIIGTERHESRRVDNQLRGRSGRQGDPGSSRFFLSLEDPLLRIFASDRVAAIMNRLKMPEGEAIEHPWVTRAIENAQRKVEQRNFDIRKQLLEYDDVSNDQRKVIYEQRNELLASVEIGDTIRAMRYDVLGETIDQHIAPGSMDEQWDVAGLEKTLAAQFTLELPLRQWLDEDKTLNEEGLRKKILAAADAAYAEKEALVGAEGLRRFERAVMLQSLDTHWREHLSALDHLRQGIHLRGYAQKQPKQEYKREAFELFSAMLAAIKAEVTQITTTVQVRAPEDVQAVELHEEPSNVQYEHAGYDEGADFAAAESAEAAPSGPVHVGPKVGRNDPCPCGSGKKYKQCHGKLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: SAT_PELPB
Sequence: MSLVNPHGREKILKPLLLSGQALQNEQERAKSMARVTLSSRETGDLIMLGIGGFTPLSGFMGYEDWKGSVEECKLADGTFWPIPITLSTTKEQADKLKIGAEVALVDEESGETMGSMTIEEKYAIDKSHECREVFKTDDPKHPGVLMVMNQGDVNLGGSVKVFSEGSFPSEFEGIYMTPAQTRKMFEDNGWSTVAAFQTRNPMHRSHEYLVKIAIEICDGVLIHQLLGKLKPGDIPADVRRDCINVLMDNYFVKGTCIQGGYPLDMRYAGPREALLHALFRQNFGCSHLIVGRDHAGVGDYYGPFDAHYIFDQIPKDALETKPLKIDWTFYCYKCDGMASMKTCPHTNEDRLNVSGTKLRKMLSEGEEVPEHFSRPEVLEVLHRYYATLTEKVDIGLQTNTGG
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: COX6C_CARSF
Sequence: MSSGALTKPQMRGLLAKRLRFHIVGAFAVSLGVAAFYKFAVAEPRKKAYADFYRNYDSMKDFEEMRKAGIFQSAK
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6C, Cytochrome c oxidase polypeptide VIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6c family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL16_NEIMB
Sequence: MLQPTRLKYRKQQKGRNTGIATRGNKVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRGGRIWIRVFPDKPITEKPIQVRMGGGKGNVEYYIAEIKPGKVLYEMDGVPEELAREAFELAAAKLPIPTTFVVRQVGQ
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SPS1_BOVIN
Sequence: MSARESFNPESYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDEQFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNPTPGATS
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase 1, Selenium donor protein 1, Selenophosphate synthase 1.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class II subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein.
Protein: ILVD_CAMJR
Sequence: MRSDAIKKGHLKAPNRSLLRACGLKDEDFDKPFIGVANSYIDIIPGHYFLNNYAKIIKDEICKNGCVPFEFNTIGVDDGIAMGHEGMLYSLPSREIIANSIETVMNAHQLDALICIPNCDKITPGMLMGALRVNVPTIFVSGGPMASGVTKKGEKISLSSVFEAVGAYEAKKISEEEFKDIECSACPSGGSCSGMFTANSMNTLCEAMGIALEGNGTILALSKEREELLRKAARRICEIALDERFKIRNIITQKAVRNAMVVDMAMGGSSNTVLHMLAISREAGVALDIKDLNFISSKVAHIAKIAPSLNSVYMDDIHKAGGVSAVMAEISSRQGHILELDALTITGESLKERLKNAKIKDENIIRKVDNAYSKVGGLAILFGNLAEQGCVIKTAGIIGERKFKGKAVCFNSQDEAIKGIIKGKVQKGNVCVIRYEGPKGGPGMQEMLSPTSLLMGMGLGADVALITDGRFSGATRGLSVGHISPEAAEGGLIGLLKDGDEIEIDVDAYTIHANVSEEEIAKRKKEFALPQKEVSSRWLRMYQKLVSNASKGAVLDME
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PITH1_DROPS
Sequence: MPHGHSHDHGGCGHEATDVDHALEMGIEYSLYTKIDAENLECLNEETEGSGKTVFKPYESRQDMSKFVQSDADEELLFNIPFTGNIKLKGIIICGANDDSHPNKVKIFKNRPKMTFDDAKVKVDQEFELTRDPRGEIEYSPKVVNFSSVHHLTLYFPSNFGDDKTRIYYIGLRGEFSEAHYHGVTICNYEARANAADHKDKVFDGVGRAIQ
What are the official names of this protein?
PITH domain-containing protein GA19395.
What is the protein family that this protein belongs to?
Belongs to the PITHD1 family.
Protein: EFTS_BRUAB
Sequence: MSISASLVKELRDLTGAGMMDCKAALAATEGKIEAAVDWLRAKGIAKADKKAGRTAAEGLVGVAASGNKAVVVEVNSETDFVARNDAFQELVRKIAQAALSTDGSSEAVANANVDGKTVTEAAKDAVATIGENISFRRSAALSVPQGVVATYIHNGVADGLGKLGVLVAIETAGDAEAAQAFGRQVAMHVAAVNPLALTSADVNPEAAEREKAIFIDQARQSGKPDNIIEKMVEGRMRKFYEEVVLLSQAFVINPDLTVEAALKDAEKAIGAPAKITGFARIALGEGIEKEESDFAAEVAAAAKG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XMT1_COFAR
Sequence: MELQEVLRMNGGEGDTSYAKNSAYNQLVLAKVKPVLEQCVRELLRANLPNINKCIKVADLGCASGPNTLLTVRDIVQSIDKVGQEKKNELERPTIQIFLNDLFPNDFNSVFKLLPSFYRKLEKENGRKIGSCLIGAMPGSFYSRLFPEESMHFLHSCYCLQWLSQVPSGLVTELGISTNKGSIYSSKASRLPVQKAYLDQFTKDFTTFLRIHSEELFSHGRMLLTCICKGVELDARNAIDLLEMAINDLVVEGHLEEEKLDSFNLPVYIPSAEEVKCIVEEEGSFEILYLETFKVLYDAGFSIDDEHIKAEYVASSVRAVYEPILASHFGEAIIPDIFHRFAKHAAKVLPLGKGFYNNLIISLAKKPEKSDV
What is the function of this protein?
Involved in the biosynthesis of caffeine (PubMed:18068204, PubMed:25133732).  Specific for xanthosine and could not use xanthosine 5'-monophosphate (XMP) as substrate.  Catalyzes the 7-N-methylation activity of xanthosine, but does not have 1-N- or 3-N-methylation activity (PubMed:18068204).
What are the official names of this protein?
7-methylxanthosine synthase 1, CmXRS1, Methyltransferase-like 3, CaMTL3, Xanthosine methyltransferase 1, CaXMT1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Type-7 methyltransferase family.
Protein: CASP9_MOUSE
Sequence: MDEADRQLLRRCRVRLVSELQVAELWDALLSRELFTRDMIEDIQQAGSGSRRDQARQLVTDLETRGRQALPLFISCLEDTGQGTLASLLQSGRQAAKQDPEAVKPLDHLVPVVLGPMGLTAKEQRVVKLDPSQPAVGNLTPVVLGPEELWPARLKPEVLRPETPRPVDIGSGGAHDVCVPGKIRGHADMAYTLDSDPCGHCLIINNVNFCPSSGLGTRTGSNLDRDKLEHRFRWLRFMVEVKNDLTAKKMVTALMEMAHRNHRALDCFVVVILSHGCQASHLQFPGAVYGTDGCSVSIEKIVNIFNGSGCPSLGGKPKLFFIQACGGEQKDHGFEVACTSSQGRTLDSDSEPDAVPYQEGPRPLDQLDAVSSLPTPSDILVSYSTFPGFVSWRDKKSGSWYIETLDGILEQWARSEDLQSLLLRVANAVSAKGTYKQIPGCFNFLRKKLFFKTS
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7).  Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner.  Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
What are the official names of this protein?
Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, APAF-3, ICE-like apoptotic protease 6, ICE-LAP6.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.