PharMolix/UniProtQA huggingface dataset:
Protein: SYY_MESHJ
Sequence: MSYIEKQEFLTELKTRNILKDISSPEKFFNLKPDQGIYIGFDPTATSLHLGNYISISLLKRLQKIGIKVLAVIGGATGMIGDPSFSSKERKLLDFKTLNANKEKIKKQLESFGLPVFDNFEIYKNMNILDFLRDVGKNINISYLLAKESVASRIEVGLSFTEFSYQLIQGWDFKFLAENYQIIGQAGGSDQWGNMVTGLDFIKKSNLVQKDEAFVFTTNLLTDENGQKFGKSLGKPIWLDPEMYSPFHLYQFLLNQNDEQAEKIMLWLSFLDLKVINELIFKHKNDKKQRILQYNLAQEVVFNIHGDKGLKIAKKITKILFEKLDYTEITFKDKLELKKIIPYFKVSFFNANQIIDLGIFKSKRELNEFISHKALEINGSKISNIGDITEELKDKSNLFLLRKGKKYFFIIELI
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_CITK8
Sequence: MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPI_OLIPU
Sequence: MNVLSCSINTLIKEGLYEISGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSSVLAIRNPQTIPTDGQNFFEFVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIQLPQGELAAPTNDINTTVALALLTSVAYFYAGLSKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GATB_ORITI
Sequence: MTFIEGKTEKWEYVIGLEIHAQIKSNAKLFSSASTEFGSSPNSQVELLDAAMPGSLPVLNEFCVHQAIKTALGINAKINKLSIFDRKNYFYADLPAGYQISQFYHPIAQGGWIEILDENGNIKRIQINRLHIEQDTGKSTHDQSDTYSYIDLNRSGIALMEIVSEPDISSPMQAAEYIKKLRAILRYLDSCNGDMEKGSLRCDANISVRKPNSELGTKCEIKNLNSIKSIVRALEFEGQRQVNILESGGTVKQESLLFDATLGKTFPMRSKENATDYRYFPDPDLPPIILDQSLIDNIASSLPELPDAKIRRYINEIKLSDYNAQVLAADKDISCFFEEVIKTANPLLSANWILSELFGLMNKDGITINECKITANHFSELIQLISSKAISSKIAKTVLKEMFDSGKSPKIIMQEKNIQQISDPNQIADIIDDVLKDNYQSVVSYRNGKDRLFGFFVGQVMKKTAGNANPALINEILHTKLKQFQI
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LOR14_ARATH
Sequence: MPKNKKTEWQVGDPAISVVSDQFCNPYPMDLLVKRKVQNFSKDYYEVFDPSGNLLLQIDGQAWGFNRKRVMRDPAGFTILSMRQKGLALKNKWEVHGGESKEREDLLFTVQQSQAVSLKTSVDVFLPENNNVKKTNTCDFHASGGYSNISFKVFKADALIAGVGFTWGSFCKGKYNFKVRVNPEVDYAFIIALLVMVDDNENWC
What is the function of this protein?
Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors.
What are the official names of this protein?
Protein LURP-one-related 14.
What is the protein family that this protein belongs to?
Belongs to the LOR family.
Protein: MRAZ_BURM1
Sequence: MFQGASALTLDAKGRMSVPARYREALQGQAEGRVTVTKHPDGCLLLFPRPEWEVFRAKIAALPMDAHWWRRIFLGNAMDVDLDSAGRILVSPELRMAAGLEKEVMLLGMGSHFELWDSQTYIAKEQAAMAQGMPDALKNFTF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: TATA_LEPCP
Sequence: MGLSTTHLIIFLVIIVLIFGTKKLKNIGSDLGGAVKGFKDGMKTGEKTEADAAAAKAAEPAAQVSAEKRIDTQTIDVEAKTK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RT02_BOVIN
Sequence: MATGAVLPRLLGAGVRAAPRGRAAQRGRTLGSAAAAAAREPERDSDRSARILSEPLKHSDFFNVKELFSVRSLFNARVHLGHKAGCRHRFMEPYIFGSRLGQDIIDLEQTATHLQLALNFTAHVAFRGGIILFVSRARQFSHLIESTARSCGEYAHTRYFKGGLLTNAPLLLGARVRLPDLIIFLHTLNNVFEPHVAVRDAAKMSIPTVGVVDTNCNPCLITYPVPGNDDSPPAVQLFCQLFQTAVTRAKEKRRQLEALYRLQGAPGPHPANPAAPGAPSPGAQAQLGMGHSP
What is the function of this protein?
Required for mitoribosome formation and stability, and mitochondrial translation.
What are the official names of this protein?
28S ribosomal protein S2, mitochondrial, MRP-S2, S2mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RUVB_CHLPD
Sequence: MKIELLNTPADALEIRYEEQIRPLKMDDFTGQQRLTDNLRVFISAAKIRGDALDHVLLSGPPGLGKTTLANIIASEMGGNIKVTSGPMLDKAGNLAGLLTSLRKGDVLFIDEIHRLPAAVEEYLYSAMEDFRIDIMLDSGPSARAVQLRIEPFTLVGATTRSGLLTSPLRARFGISSRFDYYPPELLERIILRASGILGIGVTTEAAGEIAGRSRGTPRIANRLLRRARDFAQVADSFVINHDIAMTTLASLEIDEEGLDDMDKKIMDTIVNKFNGGPVGVASLAVSVGEEQDTIEEVYEPYLIQAGYLARTPRGRVATRLALKRFSSGSGINSSEGPLFDAAPAR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PURK_BACSU
Sequence: MSKQIIYPGAVIGIIGGGQLGKMMAVSAKQMGYKVAVVDPVKDSPCGQVADVEITAHYNDREAIRKLAEISDIITYEFENIDYDALHWLKDHAYLPQGSELLLITQNRETEKKAIQSAGCEVAPYSIVKTKNELKQAVQELRLPAVLKTCRGGYDGKGQFVIKEEAQMEQAAALLEHGTCILESWVSFKMELSVIVVRSVNGEISTFPTAENIHHNNILFQSIVPARVEKGIQQKAADLAVKLADELNLVGPLAVEMFLTEDGELLVNELAPRPHNSGHYTLDLCETSQFEQHIRAVCGLPLGKTDLLKPGMMVNLLGDEVKLVEEDPELLKEAKLYIYGKHEIKKGRKMGHITFMKQPEDEWIQEITNKWMNRDGGQAE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: C124_SSV1
Sequence: MKKLFTVVGSIFSGLGIWLKSIDQSFYLTKVLYNGKVIEIVLTPETNEVVKSSNGVMNASVTSLPSTILYQAQSVPSINGGTLSVINTTVQPPWYANLWPEVLTIGIVMLGIAIFSWIKLKFRR
What is the function of this protein?
This protein may be involved in virus assembly.
What are the official names of this protein?
Uncharacterized protein C-124.
Protein: MIAA_CROS8
Sequence: MNDVSKTGLPKAIFLMGPTASGKTALAIRLRQTLPVELISVDSALVYKGMDIGTAKPDAHELSQAPHRLLDIIDPAQAYSAADFRRDALQAMAEIVAAGRIPLLVGGTMLYFKALLEGLSPLPSADPTIRAEIERQAAEQGWDALHRKLQDIDPVAAQRIHPNDPQRLSRALEVFFISGKTLTELTQTSGEALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDMPSVRCVGYRQMWSYLAGEISYDEMVYRGICATRQLAKRQITWLRGWEGVHWLDSEKPEQAYSDVLQVIGAKQQ
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CATA2_CUCPE
Sequence: MDPYKYRPSSAYNTPFCTTNSGAPIWNNTAVMSVGERGPILLEDYQLIEKIATFTRERIPERVVHARGASAKGFFEVTHDVSDLSCADFLRAPGVQTPVIVRFSTVIHERVSPETVRDPRGFAVKFYTREGNFDLVGNNFPVFFVRDAMQFPDVIRAFKPNPKSHLQESWRFLDFCSYHPESLLSFAWFYDDVGIPINYRHMEGFGVQAYSLINKAGKARLVKFHWKPTCGVKSMLEEEAIRVGGSNHSHATQDLYESIAAGNFPEWRLYIQTIDYEDQNNYDFEPLDTTIAWPEDVVPLRPVGRLVLNKNIDNFFAENEMLAFSMSLVPGIHYSDDKMLQARSFAYADTQRHRLGPNYLQLPVNAPKCPHHNNHHEGFMNFMHRDEEVNYFPSRYDACRHAEKYPMPPNVLSGKRERCVIPKENHNFKQAGDRYRSWAPDRQERFVNRFVEALSDSKVTHEVRNIWISYWTQADRSLGQKIASRMNARPNM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: URE3_ALCBS
Sequence: MELTPREKDKLLIFTAALLAERRKARGVKLNYPESIAYITATIMEGARDGKTVAELMGEGRTLLKRQDVMEGVPEMIHEVQVEATFPDGTKLVTVHDPIV
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLA_STAAN
Sequence: MNKNVMVKGLTALTILTSLGFAENISNQPHSIAKAEKNVKEITDATKAPYNSVVAFAGGTGVVVGKNTIVTNKHIAKSNDIFKNRVAAHYSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFAEGAKAKDRISVIGYPKGAQTKYKMFESTGTINHISGTFIEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
What are the official names of this protein?
Serine protease SplA.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: CUD8_SCHGR
Sequence: QFRPQPQPSYSGNTSPIPIIRYSNEISPDGSYAWSYETGNGIAADESGALENPGQKDLEAMRAQGSFSYTAPDGSPISVRYVADRDGFHPEGAHLPTPPPIPPAIQRALDFIASQPQQPGNNGGGQFPRPQPFPRPGAF
What is the function of this protein?
Component of the abdominal endocuticle.
What are the official names of this protein?
Endocuticle structural glycoprotein SgAbd-8.
Protein: PMY_PETMA
Sequence: MPPKPDNPSPDASPEELSKYMLAVRNYINLITRQRY
What are the official names of this protein?
Pancreatic polypeptide MY, PMY.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAB_RALSO
Sequence: MKKVFIKTFGCQMNEYDSDKMADVLNAAEGLVPTDTPEDADVILFNTCSVREKAQEKVFSDLGRVKALKARNPDLVVGVGGCVASQEGASIVARAPYVDVVFGPQTLHRLPELIDARRRTGRPQVDVSFPEIEKFDHLPPARVEGPSAFVSIMEGCSKYCSYCVVPYTRGEEVSRPFEDVLAEVAGLAEQGVREVTLLGQNVNAYIGKMGGTSERADFALLLEYVAEIPGIERIRYTTSHPKEFTARLIEAYATNRKLVDHLHLPVQHGSDRILMAMKRGYTVLEYKSIIRKLRAIRPDISIATDFIVGFPGETDADFAKTMDLVHEIGYDNSFSFIYSPRPGTPAANLHDDTPHAVKLERLKHLQATIDANMARISEGMVGSVQRILVEGPSRKDPSELHGRTENNRVVNFALPDLPQARRDQLVGQMLDVRIVHAYPHSLRGDVVEQRPDGVTQH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XANG_ASPFU
Sequence: MTWMRVMPRCQNRTYKRPRGPPLSIHPLEFFQAKKVEKTAKAKMILYYLASIPLAIICYLAWYLHVPWDLPSLPRIPFYVSILGLWSSMGQDEIYERWLRKPLEAHGAVLIWFAGRWSILVTRPDLLTDMFRNEDLYAKAGSQKKIPWSVIATLVGDNIINSHGDTWKLYTGIMKPGLQKKNFDTAPLLLKSRRFVDEILAEQNSAGRGTGILVNTFVQQWAVDVMGMSFLDLDLQSLEKPHGTVRLEAIQSVIKLMLFRPLFFNFPDLDQFAWLIKSRQRAYEIMHEFGDTLMATVLGRIDSDREKGIKPAEEMVVHMLVDAYRDGRLTEKQFKDNLKIVFLTAHENAQQLVNSMFWEIGKNNEVQTRLRAEILSTNTTTPTSEVVNALPYLTAVVYELLRLYPPVSQLINRVTVRPAMLGNEIPIPAGTFVGWNAYGVHVNPAIWGPDANEFKPERWGRTVGEMHARFRRETVRGTYIPFNAHSRKCLGQGFVLLQMKILLFEVLRRIEWTVDPGYRLKMTPVSYFLESGRKSTDA
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the isocyanide xanthocillin and its derivatives (PubMed:29844112).  The first step of the pathway consists in the conversion of tyrosine into a vinyl-isonitrile intermediate by the isocyanide synthase xanB (PubMed:29844112).  Subsequent oxidative dimerization of this intermediate to form xanthocillin may involve the cytochrome P450 monooxygenase xanG, whose expression is coregulated with that of XanB (PubMed:29844112).  Xanthocillin can be further modified by the isonitrile hydratase-like protein xanA which introduces N-formyl groups and the methyltransferase xanE which introduces methyl groups, leading to the production of several derivatives including fumiformamide (PubMed:29844112).  Finally, fumiformamide can be subject to both oxidative and reductive cyclization to yield melanocins E and F, respectively (PubMed:29844112).
What are the official names of this protein?
Cytochrome P450 monooxygenase xanG, Xanthocillin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYQ_VIBC1
Sequence: MSEADARPSNFIRQIIDKDLADGKHTSVHTRFPPEPNGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPEKEDIEYVESIKKDVNWLGFEWDGEVCYSSNYFDKLYEYAIELINKGLAYVDELSPEQIREYRGTLTAPGKPSPYRDRPIEENLALFEKMRAGEFEEGKACLRAKIDMGSSFMVMRDPVIYRVRFATHHQTGDKWCIYPMYDFTHCISDALEGITHSICTLEFMDNRRLYDWVLDNITIDCRPHQYEFSRLNLEYTVMSKRKLNQLVTEKLVDGWDDPRMPTVSGLRRRGFTSASIREFCKRIGVTKQENMIEFGSLESCIRDDLNENAPRAMAVLDPVKIVIENFEEGAVETLTVANHPNKPEMGEREVPFTREVWIEREDFREEANKKYKRLVLGKEVRLRGAYVIKAERIEKDAEGNITTIFCTYDAETLGKNPADGRKVKGVIHWVSADKALPAEIRLYDRLFTVPNPAAADDFAATINPESLVILNGFVEPSLAASEAEKGYQFERMGYFCADSKDSSADNLVFNRTVGLRDTWAKIENQ
What are the official names of this protein?
Glutamine--tRNA ligase, Glutaminyl-tRNA synthetase, GlnRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_STRPJ
Sequence: MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMRADLNIEEFLLLKRVLLASRELQNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHDSESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: RPOZ_PSE14
Sequence: MARVTVEDCLEHVDNRFELVMLSTKRARQLATGGKEPKLAWENDKPTVMALREIAAGLMDYAVIAEAEIVEDEPLFAAFEDESNEAV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MINE_SYNJA
Sequence: MLLDFLDQLFSRHSGNSREQAKQRLKLILAHDRADLTPAALEAMRLEILGVVSRYVELDSEGMQFHLAAEGGTTALIANLPIRRVKPLAEARLNSCEGENPQQDPGAAPSEGGHLSSPSP
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GLD2A_XENLA
Sequence: MYPNSPSLGRIPLPLPCEQQQQASGYSDKLPVSAAPELLSPEQFIQASLNIQKHANLSRMLMNGNVLTVPPVSSPPWAYLNHSPLISPGSPSSSFQNRKRRSDEGNVSYDVKRQRFHSPQEQTVNHQAVPLRGDLRCSYPGSPAFPLLQSPSPPVLKEHVSNSGDCWLYDHIDTTLPVAEDKLSQQILDLFQALQQQVCDIKKKDICRAELQREIQQIFPQSRLYLVGSSLNGFGTRISDADLCLVLKEEPMNQHTEATQILGLLHKLFYTRLSYIERLQFIRAKVPIVKFRDKVSGAEFDLNVNNVVGIRNTFLLRTYAYLESRVRPLVLVIKKWANHHGINDASRGTLSSYTLVLMVLHYLQTLPEPILPSLQKKYPECFDLSMQLNLVHHAPRNIPPYLSKNETPLGDLLLGFLKYFAVEFDWSKDIISVREGKALPRSDDYLWRNKYICVEEPFDGTNTARAVYERQKFDMIRAEFLKAWGALRDDRDLYSLLPVTAIVKKMNSL
What is the function of this protein?
Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail.  In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs during oocyte maturation.  Plays a central role during oocyte maturation by mediating polyadenylation of dormant mRNAs, which contain 5'AAUAAA-3' sequence in their 3'UTR.  In immature oocytes, polyadenylation of poly(A) tails is counteracted by the ribonuclease parn.  During maturation parn is excluded from the ribonucleoprotein complex, allowing poly(A) elongation and activation of mRNAs.  May not play a role in replication-dependent histone mRNA degradation (By similarity).
What are the official names of this protein?
Poly(A) RNA polymerase GLD2-A, PAP-associated domain-containing protein 4-A.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B-like family. GLD2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP15_HUMAN
Sequence: MAAAAPDSRVSEEENLKKTPKKKMKMVTGAVASVLEDEATDTSDSEGSCGSEKDHFYSDDDAIEADSEGDAEPCDKENENDGESSVGTNMGWADAMAKVLNKKTPESKPTILVKNKKLEKEKEKLKQERLEKIKQRDKRLEWEMMCRVKPDVVQDKETERNLQRIATRGVVQLFNAVQKHQKNVDEKVKEAGSSMRKRAKLISTVSKKDFISVLRGMDGSTNETASSRKKPKAKQTEVKSEEGPGWTILRDDFMMGASMKDWDKESDGPDDSRPESASDSDT
What are the official names of this protein?
RRP15-like protein, Ribosomal RNA-processing protein 15.
What is the protein family that this protein belongs to?
Belongs to the RRP15 family.
Protein: RL13_RICCK
Sequence: MKTYSAKPSEIEKKWWVIDAKNIVLGRLASRVANMLRGKHKPSFTPHLDCGDNIIIINAAHVKLTGKKANTKDGKIYYRHTGFPGGIKNTTAGKILAGKHPERVIKMAVKRMITRNALGAKQMSNLYVYANSDHPHVGQEPVIYDFASQNPKNKSNYL
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: AMPP2_ARCFU
Sequence: MKFRIKTLPLRTERIAVVLSQDDAAELGLLPGDRVKVSYDGKSFVAEVEISQEFISSGEAGVCTFTAETCSLSEECVVEIVPFARPKSVEYIRKKLNGAKYEREEIKDIIGSISSDVLSDIEISAFILANEIVGMQNDEIQWMIEAMVEVGERVVFERGTVVDMHSIGGLPGNRFSLIAVPTVAAAGLLIPKTASRAITTASGTADTMEVLANVNLSVDEIKEITEEVGGVIAWNAPTGIAPADEKIIRVEYQLELSPKPHLMASVLSKKLGSGARFVAIDIPVGKKAKVENVDVGRGFANAMMEIGRNLNLKVATALTDGSQPLGRAIGPALEAREVLEVMERKVEGDLLEKSLGIAGILFEMTGIATNGYQHARKIFESGKTLEKFREIVAAQGGDESVKAEDVAVGDKTYTLHAAKEGYVREIDIAALNEIARTAGAPKDKGAGVYVHKKRGEVVKVGDPLLTIYAEKEWKLDNAIEVANTKQAFEISGVIIERYTMGRWWS
What is the function of this protein?
Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P).  Exhibits phosphorylase activity toward CMP and UMP in addition to AMP.  Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.
What are the official names of this protein?
AMP phosphorylase 2, AMPpase 2, Nucleoside monophosphate phosphorylase 2, NMP phosphorylase 2.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: HUTH_CHRVO
Sequence: MSILNIVPGRLTLAELRRVSRETGLQLQLDPSSHAAIDASAATVARVLSEGRTVYGINTGFGLLASTKIAPEELELLQRSIVLSHAAGIGAPMDDSTVRLVMALKINSLARGFSGIRRQVIEALVTLFNRQIYPVIPQKGSVGASGDLAPLSHMSAVLIGEGEAFVDGVRVPGSVAMRSAGLEPITLAPKEGLALLNGTQASTAFALEGLFAAEDLYVSATVAGSLSVEAALGSRTPFDARIHEVRGHQGQIDAARLYRDLLAHSQIEQSHENCGKVQDPYSLRCQPQVMGACLTQIRQAAEVLRVEANSVSDNPLVFAGDNDILSGGNFHAEPVAFAADNLALAIAEIGSLSERRMALLIDSNLSKLPPFLVNNGGVNSGFMIAQVTSAALASENKSLAHPASVDSLPTSANQEDHVSMATFAGRRLRDMAGNTAGILAVELLAACQGIDFRAPHQSSDKLEAAKGMLREQVPFYDKDRYFAPDIEKAAALVASGRFNSLVDGEVLPSL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOMA2_XENLA
Sequence: MVPGSCSSFGLLVILSFQNVPDVGGFPNVPLFSLFTNAVNRAQHLHMLAADIYKDYERTYITDDVRRSSKNSQVVSCYSENIPAPTDKDNTHLKSDMDLLRFSLTLIQSWLNPVQALHRLFRNSDVYERLKYLEEGIQSLIRELEDGNLRSYSFMRTPYERLDINMRTDDGLLKVYGLLSCFKKDMHKVETYMKVIKCRHFAESKCVI
What is the function of this protein?
Growth hormone plays an important role in growth control.
What are the official names of this protein?
Somatotropin-B, Growth hormone B, GH-B.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.