PharMolix/UniProtQA huggingface dataset:
Protein: MTND_PARMW
Sequence: MSRLSIFPDHGDGGDGALPLPKLVCNDPASIQAELADRCVGFEQWPAAHALPPDADQSTILTTYASEVARVQRDGGYQTVDAIRMTPDHPEREALRNKFLSEHTHAEDEVRFFVEGQGLFSLHIDKEVLVTLCERGDLISVPAGTRHWFDMGPTPSFCALRFFNNSEGWVATFTGDSIAERFPRLD
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: SUCC_RICCK
Sequence: MNIHEYQAKEILRKYGIPTSTGLVVTKTEQINETIDKLNTEVYVVKAQIHAGGRGKAGGVKVVKSKEEAKKIAHDMFGINLVTHQTGPQGQKVKRLYIESGCDILKEYYFSIVFDRSASCITFIASTAGGVDIEEVAKKTPEKIVKFSVDPATGLQDFHMRGIAYELGFKDNQVKQMKEIVKSVYNAFIETDATQIEINPLIVKTDGDLLALDAKITFDENALFKHPNVTAMRDYDEEDPLETRAANAGLSYVKMDGNIGCMVNGAGLAMATMDIIKLYGALPANFLDVGGGADCERIKEAFKIILSDKKVQGVLVNIFGGIMRCDIISEGIIAAAKEIDIKVPLVVRLAGTNVEKGKKILSNSGLEIITAHDLADAANKIVEAIS
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: GUFA_MYXXA
Sequence: MGAGLVASLLAGTATGLGALPVLVTSELSRKAQGPDVGLQRGRDAGGQSFSLVIPAMELVRGQGHDGPSAALRVAAGVLLGGLFLRVWHDLMPHEHALKGHEGHGGTKWNSALLFVLAMTLHNFPEGLAVGVSFAAPQPELGLSVALGIGAQNIPEGLVVALALRASGASASRAAFLALLTGMVEPVGALFGVLALSLSSALLPWGLAFAGGAMLYVISHEMIPESHRGGFEREATTGLMWGFVLALVLDMSLG
What are the official names of this protein?
Protein GufA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL16_RALSO
Sequence: MLQPKRRKYRKEQKGRNTGIATRGNAVSFGEFGLKAMGRGRLTARQIESARRAMTRHIKRGGRIWIRIFPDKPISKKPAEVRMGNGKGNPEYYVAEIQPGKMLYEMDGVGEELAREAFRLAAAKLPIATSFVVRQVGT
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: FPG_VIBPA
Sequence: MPELPEVEVSRMGISPHMVGQTIKAFVFRTPKLRWDIPQELKLLEGQVIRNIRRRAKYLLIDTDQGTAIVHLGMSGSLRVLDADFPAAKHDHVDLKLTNGKVLRYNDPRRFGAWLWCAPGESHAVLEHMGPEPLTDAFNSEYIADKAQGKRVAVKQFIMDNKVVVGVGNIYANESLFKSRILPTRQAGQVTPQEWVLLVENIKATLKIAINQGGTTLKDFAQADGKPGYFAQELLVYGKAGEPCPECGEPLQELKIGQRNTFFCNECQQ
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TUSA_PSESM
Sequence: MSEPIESLTVDAVLDATGLFCPEPVMMLHQKVRDLPPSGLLKVIATDPSTCRDIPKFCVFLGHELVAEQAEESTFLYWIRKKSD
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFA_SALG2
Sequence: MLKTTLLFFVTALCEIIGCFLPWLWLKRGASVWWLLPAAASLALFVWLLTLHPAASGRVYAAYGGVYVCTALLWLRVVDGVRLTVYDWCGALIALCGMLIIVVGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TIG_STAAR
Sequence: MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGKDFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVVENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVTFPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRLAEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTYFQISGQDESQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: XYL1_PICST
Sequence: MPSIKLNSGYDMPAVGFGCWKVDVDTCSEQIYRAIKTGYRLFDGAEDYANEKLVGAGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLFLIHFPVTFKFVPLEEKYPPGFYCGKGDNFDYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSFVELNQGRALNTSPLFENETIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENKDVNSFDLDEQDFADIAKLDINLRFNDPWDWDKIPIFV
What is the function of this protein?
Reduces D-xylose into xylitol.  Has a preference for NADPH, but can also utilize NADH as cosubstrate.
What are the official names of this protein?
NAD(P)H-dependent D-xylose reductase, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: UPPP_RHOPB
Sequence: MLSDILRAVILGIVEGVTEFLPVSSTGHLLLAERFFDLGDTNFWKSFTILIQLGAILAILALYFAKLWRIALGMFSDPAAQRFVIGVLVAFLPAAVIGALAGGYIKSYLFNPWVVCFSLIVGGAILLWVDQLDLQPTQDEATAFPLPMYLYIGCAQCLAMIPGVSRSGATIVGAMLLGADKRAAAEFSFFLAIPTMVGAFVYDLYKNRADMTMDHSLIVAIGFAVSFVTAIIVVKSFLAYVTRHGFTLFAWWRVIVGTLGLIALALGK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNME_DESHY
Sequence: MDDTIIALATAVGEGSIHVLRLSGPQAQEIIERAFTPHHPQRWQEKSNFTLHLGYFRAGAKVLDEVLIGRMSAPGSYTGEDVYEINCHGGLYIAERIMRECIGLGARLAEAGEFTKRAFLNGKLDLIQAEAIVDLIAAKTDSSADLALAQMEGLLSQKILLLKDQVMETLAFIEAGIDFPEDDVESLDRDALLQRISKGLELARDLLDGSKTGRILREGMLTVIVGQPNVGKSSLLNALMGEERAIVTDIPGTTRDEIRESVTIGGILLQLVDTAGLRESEDLVEKLGIERSWKAMEKAELILLIIQAGQELKAEELKILSQYDQSVIVLINKMDLLAGKERGEEVLENYPTQQGVWIPFSVKENLGFKQLEKEIKQRVYQGKAEKTKEPLLSNIRQITALERAVSALANGWDSVKNGLPWDMVSIDIRQALQEISQMTGDSVQESLLDDIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_ECODH
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: YBEY_HAHCH
Sequence: MSLDVDIQIASEEADLPSEEQLILWAQAALRETGDREVTIRIVDAEESRELNAQYRGKDKPTNVLSFPFENPPGLTLPLLGDLVICAPVVFNEAVEQQKTAAAHWAHMVIHGMLHLQGYDHIIDEEAEVMESLETELVTSLGFPPPYATNSSLAEG
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIN_METJA
Sequence: METKHIILLAIVAIIIALPLIIYAGKGEEEGYFGGSDDQGCEVVEELGYKPWFHPIWEPPSGEIESLLFALQAAIGAIIIGYYIGYYNAKRQVAA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXA_ECOL5
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDCS_STAAR
Sequence: MAYFNQHQSMISKRYLTFFSKSKKKKPFSTGQLIGLILGPLLFLLTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYIMPIVLGIDINQPLPLK
What is the function of this protein?
Mediates the transport of the dicarboxylates fumarate, malate, and succinate across the cytoplasmic membrane via a Na(+)-electrochemical gradient.
What are the official names of this protein?
Sodium-dependent dicarboxylate transporter SdcS, Na(+)/dicarboxylate symporter.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGA2_SCHPO
Sequence: MGFDVAGYLQSYSLKDWIRIIVYVGGYMLIRPYLMKLGAKIQEREHRKSLLEGEVDGTLDPEMTHGTKPKEHGEFDTDDEEEEENPDAEFRWGYSARRRIRKQREEYFKNQDKSPLDAYADDDEDIEEHLED
What is the function of this protein?
Involved processing and trafficking glycosylated proteins.
What are the official names of this protein?
PGA2-homolog C27.01c.
What is the protein family that this protein belongs to?
Belongs to the PGA2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Nucleus membrane; Single- pass membrane protein.
Protein: ADE_PSEA7
Sequence: MYEWLNALPKAELHLHLEGTLEPELLFALAERNRIALPWNDVETLRKAYAFNNLQEFLDLYYAGADVLRSEQDFYDLTWAYLQKCKAQNVVHVEPFFDPQTHTDRGIPFEVVLAGIRAALRDGEKQLGIRHGLILSFLRHLSEEEAQKTLDQALPFRDAFVAVGLDSSEVGHPPRKFQRVFDRARSEGFLTVAHAGEEGPPEYIWEALDLLKVERIDHGVRAFEDERLMRRLIDEQIPLTVCPLSNTKLCVFDDMSQHTILDMLERGVKVTVNSDDPAYFGGYVTENFHALQQSLGMTEEQARRLAQNSLDARLVK
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: Y1472_SHEB5
Sequence: MQYQVDTHTHTVASSHAYSTIHDYIAVAKQKGIRLFANTDHGPAMADAPHFWHFVNLRVLPRMVDGVGILRGIEANIKNIDGEIDFFGDYLKQLDIVLAGFHEPVYPPSDKATHTEAMINTIKSGKVDIITHPGNPAYPIDIEAVARAAAEYGVALEINNSSFEVSRKGSEANCTAIAKAAKEFGTILVMGSDSHVAFSLGGFARAQAIIDEVAYPPSRLLNRSPSALLAFLAARGHETVADLIPLFSDDEPCC
What are the official names of this protein?
Probable phosphatase Sbal_1472.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: DAPE_XYLFM
Sequence: MSEVFDLTCDLISRPSVTPEDAGCQAMIAARLERVGFTCEHLHYGSVANLWATHGQGAPVLVLLGHTDVVPPGPIEAWTSNPFIPQRREGKLYGRGAADMKGSVAAFVIAAERFLVAHPGHPGTLAILLTSDEEGQAIDGVRKVAETLRQRGQRIDWCLTGEPSSSERLGDLLRVGRRGSLSATLHVKGVQGHVAYPHQARNPIHLAVPALAALTGRHWDDGDESFPSTSLQISNIHAGTGANNVIPGALEVAFNLRYNPHWSAPRLESEIVALLDQHGLDYTLHWHRSGEPFYTPEGKLRRIAREVLERFSGAPPEESTGGGTSDARFIAPLGAQCIEVGPVNASIHQVDEHVCLADLEALPDLYQLLIERLLAEH
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: DSBD_VIBPA
Sequence: MRALLSVLLLGLITFSTPSLALFGKDQFNNSQNNSFGSSNDSFVPVDQAFPFNFYQQDDKLMLDWQVRDGYYLYQERLSVSGENISLGELQMENGTPHKDEFFGDVHIYTTPLFVNVPLDEWQEGARVIVQYQGCAKAGFCYPPETRIIPIDAFTASIADSAVATKPTQSTANNNQTNATSPTASTSVSSNNTPAPVTEQDSLAANLADNWWTPLLFLALGVGLAFTPCVLPMYPILTSIVLGSGKLSQRRALGLSLVYVQGMALTYTLLGLVVASAGMQFQAAMQHPYVLIGLSILFVTLALSMFGVYTLQLPSSVQTWLNNLSNKQQGGSSAGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGGIALYALAMGMGIPLILVAVFGNKLLPKAGGWMDRVKTLFGFILLAAPIFLLERILPEMWSTALWSALGIAAFGWLYHIKNSLEFGGWKQSAIGIIAVLGLFASAQPALNYWFGNHETQAQQTTVSFTRIANVAELEEQLALAKAAGKPVMLDFYADWCVACKEFEKYTFHDPKVEAKLQDFVLLQADVTKNQVQDIELLKHMNVLGLPTIEFWDAKGEHVSNARLTGFMQAEPFLEHINRF
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TYSY_BUCA5
Sequence: MKQYIKLIKKIIRVGNQKKDRTGTGTLSIFGYNMKFDLKKGFPLLTTKKCHIASIIYELLWFLKGDTNIAYLNENKISIWNNWANESGDVGPIYGKQWRNWSTPEGHEIDQIKNVLIQLKKNPDSRRMLVSSWNVGDIDKMRLPPCHVLFQFYVFNNTLSCQLYQRSCDVFLGLPFNIASYSILIHMIAQQCDLKVGDFLWTGGDVHLYNNHIELAKKQILRIPRTLPKLTILKKPQSLFQYCFEDFKIIGYHPYPAIKGKISI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNPY1_XENLA
Sequence: MAILLHFGVLITAFLSSHVEGKRDPILYCGACRALVDELLYEIRKVNPKKTVDVGSFRISPDGKQEQNKVPFAKSELYLTDVLEEICEKMNDYGLYVDPTTQEKSYKRFAPRDNEGIGSVDFKNFQFNPEESNSLKYACERVVEEHEDEVLSVITKENDNLADKLCTEETGLCKEYLHNEL
What is the function of this protein?
Plays an role in early embryonic development.
What are the official names of this protein?
Protein canopy homolog 1.
What is the protein family that this protein belongs to?
Belongs to the canopy family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: WHIA_CLOBL
Sequence: MSFSLKVKNEVCKHVEVNKQEAIAELSAIMKVSGTLLFTNKQFNFKITTENAAIARLVFKILKEHFGIHTEIMIKKNNSLKKNNIYIILISEEEGVKSLLKEVGIIKETINVFSLDYNIPKSIIECDECRRAYIRGAFLGGGSISNPEKTYHLEFVTHNEEYAKDLSNLINSYNLNSKVIKRKNSYIIYLKEGEQIVDLLNIIGAHASLLELENVRIMKEMRNNVNRLVNCETANLSKTVNAAVRQVESIKFIEREIGLGRLPKNLRDVAELRIKYPDESLRELGKMLNPPVGKSGVNHRLRRIEKIADELKQGI
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: AROK_BARHE
Sequence: MKSNRPKHIPITKIKNQLLSSLDNRALVLIGLMGVGKSVIGKRIATMLCLPFYDSDQEIEKAAQMTITELFKTYGESEFRALEQRVILNLMKNRPLVLATGGGAYINEDIRKAVHKNGISIWLKVDLDTLMQRVSKRPTRPLLQTENPKETMQKLMKQRYPIYAKANLTINSHKENRQTVAQNVIRSVQHYLDTEKNDRNNQHANQNCHC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMF_PSYCK
Sequence: MTSKPMNRRPTANNHRNRSPETAKKLGQLHPRNPHQGRYDFEVLTRALPELAKHTITNPKGESTINFSDSAAVRVLNQALLANYYGVKFWDIPEGYLCPPIPGRADYIHYIADLLAQTTHVNKDNTPPTGKEIHALDIGTGASAIYPIVGSQSYGWRFTASDIDPISVNTAALICETNPKLKSAVKVKLQTEPKFIFKNIIGRQDYFDVVVCNPPFHASLEEAMEANSRKQHNLQRHRGKNENEQISRSSTKPGNAAQNLNFGGQHKELWSEGGEIAFLTKMAKESQDFAEHVGWFTTLVSKSENVKPLQLLLKQLGVAQMRIIEMSQGQKSTRILAWRFNTDEE
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S26A5_MERUN
Sequence: MDHAEENEIPVATQKYHVERPIFSHPVLQERLHVKDKVSESIGDKLKQAFTCTPKKIRNIIYMFLPITKWLPAYKFKEYVLGDLVSGISTGVLQLPQGLAFAMLAAVPPVFGLYSSFYPVIMYCFFGTSRHISIGPFAVISLMIGGVAVRLVPDDIVIPGGVNATNGTEARDALRVKVAMSVTLLSGIIQFCLGVCRFGFVAIYLTEPLVRGFTTAAAVHVFTSMLKYLFGVKTKRYSGIFSVVYSTVAVLQNVKNLNVCSLGVGLMVFGLLLGGKEFNERFKEKLPAPIPLEFFAVVMGTGISAGFNLHESYSVDVVGTLPLGLLPPANPDTSLFHLVYVDAIAIAIVGFSVTISMAKTLANKHGYQVDGNQELIALGICNSIGSLFQTFSISCSLSRSLVQEGTGGKTQLAGCLASLMILLVILATGFLFESLPQAVLSAIVIVNLKGMFMQFSDLPFFWRTSKIELTIWLTTFVSSLFLGLDYGLITAVIIALLTVIYRTQSPSYKVLGQLPDTDVYIDIDAYEEVKEIPGIKIFQINAPIYYANSDLYSNALKRKTGVNPALIMGARRKAMRKYAKEVGNANIANAAVVKVDGEVDGENATKPEEEDDEVKYPPIVIKTTFPEELQRFMPQTENVHTIILDFTQVNFIDSVGVKTLAVMVKEYGDVGIYVYLAGCSPQVVNDLTRNRFFENPALKELLFHSIHDAVLGSHVREAMAEQEASAPPPQDDMEPNATPTTPEA
What is the function of this protein?
Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ.  Prestin is a bidirectional voltage-to-force converter, it can operate at microsecond rates.  It uses cytoplasmic anions as extrinsic voltage sensors, probably chloride and bicarbonate.  After binding to a site with millimolar affinity, these anions are translocated across the membrane in response to changes in the transmembrane voltage.  They move towards the extracellular surface following hyperpolarization, and towards the cytoplasmic side in response to depolarization.  As a consequence, this translocation triggers conformational changes in the protein that ultimately alter its surface area in the plane of the plasma membrane.  The area decreases when the anion is near the cytoplasmic face of the membrane (short state), and increases when the ion has crossed the membrane to the outer surface (long state).  So, it acts as an incomplete transporter.  It swings anions across the membrane, but does not allow these anions to dissociate and escape to the extracellular space.  Salicylate, an inhibitor of outer hair cell motility, acts as competitive antagonist at the prestin anion-binding site (By similarity).
What are the official names of this protein?
Prestin, Solute carrier family 26 member 5.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Note=Basolateral wall of outer hair cells.
Protein: GPI10_EMENI
Sequence: MPMSARSRRSNPRLPPSPSSSSSSDAVRASPHSSPPSRLRPPSANPDVSSNILLFLIGFRLVNALTVRTFFQPDEFFQSLEPAWKIAFGTNQGPWITWEWEHQLRSSLHPLIFAAVYTVADLVARTLGLTPTSRAELLIAGPGITQAVIAAVGDFYTWKLARYIYGDRSHESWATVRIRSNAIEADADQLQLALTVVSLASVALYRSAWGERQTLAREALICGSSVLAVSTVVDRFFYGFWTFPPLRFLYFNVAQSLAAFYGRNDWSYYASQGYPLLLTTALPFTLVGLYRTLKTPPKLEKQKGSILVQLASISLAMPATLSVITHKEVRFIYPLLPALHILSASPLVEFFIPALTTTNREYISRRLTLIFLLWANVAIAIYTTLFHASGVISVLSYIREQHQIHGTANIPSLPKESPASYGGITTGFLMPCHSTPWRSHLVEPTIHAWALSCEPPVGLTAEEKAAYRDEADQFYDNPTQFLQDNMVGGLRHIPRRPSYATPPSSQRQPTQLFPPHEWPDYLVFFAQLEPTLKDALRGSSYGECWRTFNSAWHDDSRRRGDVVVWCLDHAKQQAWQSQKHQRELEDRDRQFDHIIKRFQRDATPSKSWHWSHWTSPFSSQSKSWSWPWERKKRTLFGYELPDLPQWGWFGKRKKKTLLSDFWF
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 3, GPI mannosyltransferase III, GPI-MT-III, Glycosylphosphatidylinositol-anchor biosynthesis protein 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family. PIGB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.