PharMolix/UniProtQA huggingface dataset:
Protein: KDPB_STAAC
Sequence: MHHVNKYFNQTMVIEALKMSFYKLNLKQLIKNPIMFVVEVGMILTLILICFPDIFGTSYLSRGYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQSNLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESAPVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIALFTLLTTLTIIFLVVIVTLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGMDRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMLEKLIVAAYMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKPFTAETRMSGIITNEISVFKGAPNSMINLVKQQQGNIPLNIESLCMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVERFTELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIVAMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMTRGALTTFSLANDVAKYFAILPALMMSTIPEMTSLNIMHLSSPKSAIISALIFNALIIVALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YRJE_LACLA
Sequence: MNDNNVIFDQRSDGLNAFFSKIYALMGAGVLVSALVSWIMITFFLDNMTAILQSGSLFFLVLWIIPLVMVVSLQGLAMKNSKMALPIFIGYAAFMGFLISFTLLMYTATDITLAFVTAAAMFFGLSVYGRFTKRNLSAMGKAFGVAVWGLIIAMFLNFFFASTGLTILISLVGVVIFAGLIAWDNQKITQVYNANNGQVSDGWAISMALSLYLDFINMFLFLLRLFGIAGGNRD
What are the official names of this protein?
Uncharacterized protein YrjE.
What is the protein family that this protein belongs to?
Belongs to the BI1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MED31_TAESO
Sequence: MQNRPKSVLTPARLGTSGVVRNTLEDPWVRFQIELEFVQSLGNPDYLTFLAQQGCFDKPEFINYLSYLQYWKSPSYSRFITYPFCLHMLDLLQSPDFRREVAHESVTRFIDDQMLLHWKNYLRKRAEMVNKHVQSLDAMATPGPGPSS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS19_LIMRD
Sequence: MGRSLKKGPFADASLLKKVKEQEGSEKKTVIKTWSRRSTIFPSFIGYTFAVYDGRKHVPVYVQEDMVGHKLGEFVPTRTFHGHASDDKKTGK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RUVA_ECO57
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: EIF3G_DICDI
Sequence: MTSTNIDNRVPIEKTIEVIVKNDKGEEVKVIKRYQEYQITVKRNRKVDERKKWKKFGECDNKTGLENTAYGDEQFLVLTRGAEVKEEEKDVVKCRICKKNHFTTKCPYKDALELTTQPQKSEKEEKPISNKYIAPNLRGGYTGSAPSGSDVPSIMVSNLSQNATEKDLYELFGQFGPVSRVSIPKSMEGSSKGFAYVTYNHLDSAEKALKQLNGHRYDYLVLSLEFAKKKSLN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.  This subunit can bind 18S rRNA.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Eukaryotic translation initiation factor 3 subunit 4.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit G family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_LACLA
Sequence: MELKDYIATIENYPKEGVVFRDISPLMADGNAYNYAATEIVQYARDKEIDMVVGPEARGFIIGCPVAFALGVGFAPVRKPGKLPREVIEATYEKEYGTDTLTMHSDSIKPGQRVLIVDDLLATGGTIAATIELVEKMGGIVVGCAFLIELDELKGREKIGDYDYKVLMHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO3_STRMU
Sequence: MSELFKKLMDQIEMPLEMKNSRVFSSADIVEVKVYPESRIWDFRFSFETILPIDFYQELRSRLVTSFETADIKAVFDIEVENAEFSNELLQAYYQEAFKQPTCNSASFKSSFSHLTVSYTDGKVLISAPQFVNNDHFRKNHLPNLEKQFEAFGFGKLSFDIVSNQKMTEEIKHHFESSRQQQIQKASQETLEIQKSLEASIPPEEIPKPVSNFKERIKDRQAAFEKAEITPMAEIETEENRITFEGLVFDVERKTTRTGRHIINFKMTDYTSSFPMQKWAKDDEELKKYDMISKGAWLRVRGNIENNPFTKALTMNVQNVKTIVHKERKDLMPQGEKRVEFHAHTNMSTMDALPTVEQLVAKAAQFGHPAVAITDHGNVQSFPHGYHAGKKNGIKVLFGLEANLVEDRVPIVYNEVDMDMNEATYVVFDVETTGLSAINNDLIQIAASKMHKGNIVEQFDEFIDPGHPLSQFTTDLTGITDQHVKGAKPISQVLQEFQSFCQDTVLVAHNATFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKRFQVSLEHHHMANYDAEATGRLLFIFLKEAKEKHGVNNLLDLNTKIVDDNSYKKARVKHATIYVLNQKGLKNLFKLVSLSNVTYFAGVARIPRTILDQYRDGLLLGTACSDGEVFDTVLSKGVEDAVEVAKYYDFIEVMPPALYEPLLARELIKDEAGIQQIIKDLIEVGRRLDKPVLATGDVHYLEPEDEIYREIIVRSLGQGAMINRPIGRGENAQPAPLPKAHFRTTNEMLDEFAFLGEDLARDIVIKNPNEMVERFEDVEVVKTDLYTPFIENSEEKVAEMTYEKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYICPNPDCKHSEFITDGSVGSGYDLPDKICSECGTPYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEEYAFRAGTVGTVADRTAYGFVKGYERDYGKFYRDAEVDRLAQGSAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDLTAEWQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPKTIPADDPEVMKLFSGTEVLGVTEEEIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKQGIATLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGAWLKISEEERNGYISAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMADISQKRKINQASNVEIDLFTTLEIVNEMLERGFKFGQLDLYRSDATEFIIDGDTLIPPFVALEGLGENVAKQIVKARNEGEFLSKTELRKRGGLSSTLVEKMSDMGILGSMPEDNQLSLFDDFF
What is the function of this protein?
Required for replicative DNA synthesis.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.
What are the official names of this protein?
DNA polymerase III PolC-type, PolIII.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. PolC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSP4_MOUSE
Sequence: MPAPRAAAAAFLLLHLVLQPWQRTSAQATPQVFDLLPSSSQRLNPSALQPVLTDPTLHEVYLISTFKLQSKSSATIFGLYSSSDNSKYFEFTVMGRLNKAILRYLKNDGKIHLVVFNNLQLADGRRHRVLLRLSNLQRGDGSVELYLDCAQADSVRNLPRAFSGLTQNPESIELRTFQRKPQDFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATSTGDFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPLSFQSPTPNTLVPIAPPAPPTRPTRHCDSSPCFRGVRCTDTRDGFQCGPCPDGYTGNGITCSDVDECKYHPCYPGVRCVNLAPGFRCDACPVGFTGPMVQGVGINFAKTNKQVCTDVDECQNGACVLNSICINTLGSYRCGPCKPGYTGDQTRGCKTERSCRNPEQNPCSVHAQCIEERQGDVTCVCGVGWAGDGYVCGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLTHNIDQRNSDKDIFGDACDNCRMVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPRVPNRDQQDRDGDDVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSSQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNNDGVGDICEADFDQDQVIDHIDVCPENAEITLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQSFDRLDN
What is the function of this protein?
Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling.  Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling.  Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload.  May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury.  May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
What are the official names of this protein?
Thrombospondin-4.
What is the protein family that this protein belongs to?
Belongs to the thrombospondin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: PYRG_GLUOX
Sequence: MTRFVFITGGVVSSLGKGIASAALAALLQARGYKVRMRKLDPYLNVDPGTMSPYQHGEVFITDDGAETDLDLGHYERFTGVHASRADNTTTGRIYSDVIARERRGDYLGGTVQVIPHITDAIKDVVVTGTDDYDFVLVEIGGTVGDIESLPFLEAIRQLRNDLGHAQTMCVHLTLLPYIPAAGELKTKPTQHSVKELQNVGIQPQMLLCRSDRPIPDNERRKIANFCNVRPEAVIAALDVDTIYACPISYHNEGMDQEVLRYFDLPYDSKPDLSRWEKIVHAIREPEGEVRVAIVGKYTALLDSYKSLAEALLHGGIANHVKVKLDWIESEEFEKNGNIAERLKDADAILVPGGFGERGAEGKIQAVRYAREHNIPFLGICFGMQMAVIECARSLAGLPKASSTEFGPTDEPLVGLMTEWARGSEMLRRREGGDLGGTMRLGAYPAKLVPGSRVAEIYGRTEIRERHRHRWEVNAHYKDRLEKTGLRFSGLSPDGVLPEVVEYPDHAWFVAVQYHPELLSKPFDPHPLFAGFIAAAVKEAHRK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: Y1406_STAS1
Sequence: MEIELSNNAVSWFKEELELPEGDKVLQFFVRYGGEFQLKQGFSPAFSVDKKEDVEIGYENHYDGLDVVIAEKDLWYFEDHNLFIDVNDGIDEISYATK
What are the official names of this protein?
Uncharacterized protein SSP1406.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ATPL_MESFL
Sequence: MLFTDYMANFLVGYFSVLSSIMPLLAETSSTGEGLKLLGAGVAIIGVAGAGIGQGAVGQGACMAIGRNPEMAPKITSTMIIAAGIAESGAIYALVVAILLIFVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSXA_ECO5E
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECA_CLONN
Sequence: MGLFEKIFGTYSSREIKKIIPIINKIDSYEEEFKKLTDEELRNKTDEFKDMLAKGKTLDDILPEAFAVAREASARVLGMRHFREQLIGGIVLHQGRISEMKTGEGKTLVATLPAYLNALSGKGVHVITVNDYLAKRDRDQMSQLYGFLGLTTGVIVHDLDNEQRREAYNCDITYGTNNEFGFDYLRDNMVIYKEERVQRKLNFCIVDEVDSILIDEARTPLIISGEGDNSTDFYKVADFFAKTLKEDDYTVDEKTNSVILTEQGIEKAEKFFHIDNYGDGDNMQIQHHVVQALKANYTMKRDKDYMVKDNEVIIVDEFTGRLMEGRRYSDGLHQAIEAKENVKIQKESKTLATITFQNYFRMYTKLSGMTGTAQTEEAEFREIYGLDVIVIPTHRPIARIDAPDVVYKSEKAKFKAIVNEIAETYKKQQPVLVGTVSIEKSELLSDMLKRKGVPHQVLNAKYHEKEAEIISHAGEKGMVTIATNMAGRGTDIKLGEGVEEVGGLKVIGTERHESRRIDNQLRGRSGRQGDPGYSRFYVSLEDDLMRIFASDRLQGVVEKLGLTDEDAIESRMVSNAIENAQKKVEGNNFDVRKSVLQYDDVMNQQREVIYKQRSQVLEGESLKEDIQEMIRSVISEAVDAHMSGLDETLEEDLEKLLAYLQEIYLPKNVVTVDELKIKSDDEIKEILIDIAEKMYSEKEEEVTPERMREIESVILLRIVDTKWMDHIDNMDHLRQGMGLRAYRQQDPVQAYQFEGSEMFDEMINGIKTDTVKYLFHIQVEKNIERERVARETSTNINDGEGGSHEPIKRKEEKIGRNDLCPCGSGKKYKNCCGR
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: Y1560_STAES
Sequence: MAKKVAIILADEFEDIELTSPKEALENAGFETEVIGDTANHEVVGKHGEKVTVDVSIADAKPENYDALLIPGGFSPDHLRGDEEGRYGTFAKYFTKNDVPTFAICHGPLVLVDTDDLKGRTITGVINVRKDLSNAGANVVDESVVVDNNIVTSRVPDDLDDFNREIVKKLEA
What are the official names of this protein?
Uncharacterized protein SE_1560.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family.
Protein: EPD1_CARAU
Sequence: MHTVKLLCVVFSCLCAVAWASSHRQPCHAPPLTSGTMKVVSTGGHDLESGEFSYDSKANKFRFVEDTAHANKTSHMDVLIHFEEGVLYEIDSKNESCKKETLQFRKHLMEIPPDATHESEIYMGSPSITEQGLRVRVWNGKFPELHAHYSMSTTSCGCLPVSGSYHGEKKDLHFSFFGVETEVDDLQVFVPPAYCEGVAFEEAPDDHSFFDLFHD
What is the function of this protein?
May play a role in neural plasticity.  May be involved during axon regeneration.
What are the official names of this protein?
Ependymin-1, Ependymin I, EPD-I.
What is the protein family that this protein belongs to?
Belongs to the ependymin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_MYCSS
Sequence: MTPADLADLLRTTATAVLTERDLDTAALPATVTVERPRNPEHGDYATNLALQVGKKVGVNPRELAGWLAEALTATAGIASAEVAGPGFVNLRIEAAAQNVIVGDIITSAERYGHSAALAERNINLEFVSANPTGPIHIGGTRWAAVGDALGRLLATQGAAVVREYYFNDHGAQIDRFVSSLIAAAKGEPTPEDGYAGSYIGDIAAQVLAKDPGALELPDDEMRETFRAIGVDLMFDHIKISLHDFGTDFDVFTHEDSMHTSGRVEEAIARLRENGAIYEKDGATWLRTTDFGDDKDRVVIKSDGAPAYIAGDLAYFLDKRQRGFDLCIYMLGADHHGYIARLKAAAAALGDDPDTVEVMIGQMVNLVRDGQPVRMSKRAGTVITLDDLVEAIGVDAARYSLIRSSVDTPIDIDLALWSSASNENPVYYVQYAHARLSALARNAADLGVVADTAHLDLLTHDKEGTLIRNLGEFPRVLESAAALREPHRVCRYLEDLAGDYHRFYDSCRVLPQGDEAPGSLHQARLALCQATRQVIANGLAILGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPPH_RICBR
Sequence: MNKTSKKHLALPYRPGVGMMILNADNKIFVGKRIDTKISAWQMPQGGIVPGETPSIAAMREMLEEIGSSKGYIIAESKCWYSYDVPSFLIPKLWDGNFRGQKQRWFLIRFTGTNEDININTLNPEFDEWRWASLDELLSIIIPFKRKLYQAVVKEFESLIQ
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: FLIC_SHIFL
Sequence: MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQASTGTNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKDGSMKIQVGANDGQTITIDLKKIDSDTLGLNGFNVNGGGAVANTAASKADLVAANATVVGNKYTVSAGYDAAKASDLLAGVSDGDTVQATINNGFGTAASATNYKYDSASKSYSFDTTTASAADVQKYLTPGVGDTAKGTITIDGSAQDVQISSDGKITASNGDKLYIDTTGRLTKNGSGASLTEASLSTLAANNTKATTIDIGGTSISFTGNSTTPDTITYSVTGAKVDQAAFDKAVSTSGNNVDFTTAGYSVNGTTGAVTKGVDSVYVDNNEALTTSDTVDFYLQDDGSVTNGSGKAVYKDADGKLTTDAETKAATTADPLKALDEAISSIDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: ARAP2_MOUSE
Sequence: MSSVSEVNADIRDFLMSINLEQYLLHFREFGFYTVRDCTSINDSVLHQIGISPTGHRRRILKQLQMIFSKMQDFPIYANVHKAKNGSTTKEQQHSDPSSSTHTGIECSDSITVHRPGPAPSEMVTTSTLSEGNCQSPKSHDKLCLSSHDLLCPEEELHQNVDSSKDSLFGGVNVKIDPLITKRAVEYTAGEEHTEKGNLTSEDSSKALSTNTECLPSGDCPTSGTHSGNGTNGVLESFPPTPFFQFQGEMVVNELYVPSSPVHGPMRSRSKLVSRPSRSFLLRHRPVPEIPGSTKSIPGSYFRDRRSNTTSAGKSLTLKNSNEDNSTSIFPYGETFLFQRLESSKKRSIKNEFWPHENTVKEEAATTRNSILTQSSIYDNRKEKVSEDKVEDIWIPREDKNNLAQDSASESEYSTVEECFQSLRRKNSKASKSRTQKAFYLDPFNRHSYPLSSTSGNTEPSSTISNAISPYACFYGSSAAKEKCGWLDKLSPQGKRMFQKRWVKFDGLSISHYNNDREMYSKGIIPLTAISTVRAQGDNKFEIVTTQRTFVFRVEKEEERNDWISILLSALKSPSLASQLQAAVAPEKCGYLELRGYKAKIFTVLRGNSVWLCKNEQDFKSGLGITIIPMNVANVKQVDRAVKQSFEIITPYRSFSFTADSEREKQEWIEAVQQSIAETLSDYEVAEKIWFNESNRSCADCKAPDPDWASINLCVVICKKCAGQHRSLGPKDCKVRSLKMDASIWSNELIELFIVIGNKRANDFWAGNLQKDEELQVDSPVEKRKNFITQKYKEGKFRKTLLASLTKEELNKALCAAVVKPDVLETMALLFSGADVMCATGDPVHSTPYLLAKKAGQSLQMEFLYHNKFSDFPQYDAHFEGGSSQDAAQSSFLCDFLYQTAAAASRVSSEKKLLEDTNKKWCVLEGGFLSYYENDRCTTPNGTINISEVICLAVHKEDFYLNTGPIFVFEIYLPSERVFLFGAETSQIQRKWTETIAKRFVPFVAENLTEADYDLIGQLFYKDCHALDQWRKGWFAMDKSSLCFCLQTQEAQEERMNLRRLQELTISTMVQNGEKVDVLLLVEKGRTLYIHGHTKLDFTVWHTAIEKAAGTDGNALQDQQLCKNDVPIIVNSCIAFVTQYGLGCKYIYQKDGDPLHISELLESFKKDARSVKLRAGKHQLEDVTGVLKSFLSDIDDALLTKELYPYWVSALDTQDEKERTSKYRAFIRSLPGVNRATLAALIEHLYRVQKCSEINHMNAHNLAMVFSSCLFQTKGQTSEEVNVIEDLINNYVEIFEVKEDQVKQMDIENSFITKWKDTQVSQAGDLLIEVFVERKEPDCSIIIRISPVMEAEELTNDILAIKNIIPMKGDIWATFEVIENEELERPLHYTENVLEQVLQWSSLAEPGSAYLVVKRFLTVDSIKQCREKSIKEGILKLKEEPSKILSGNKFQDRCVVLRDGHLFIYKDPKSSKHDKMFPLRAMKFYLGVKKKMKPPTSWGLTVYSEKHHWHLCCDSLQAQMEWMASIFIAQHENDIWPPAGKERKRSITKNPKIGGLPLIPIQHERNATQARKNIETARAELERLRLSEKHDPRDFTDSSLKDRASLIAHCLEHKDEKLRNRARKHRSFNCLEDTEAEGPHGLPKAYKGPKTLKKTEERNSKATLDADPKLPSKVIEELSVVLQRSRPLHKELPDEQTLQKEVK
What is the function of this protein?
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members.  Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding.  Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency (By similarity).
What are the official names of this protein?
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2, Centaurin-delta-1, Cnt-d1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMACL_HUMAN
Sequence: MTDTAEAVPNFEEMFASRFTENDKEYQEYLKRPPESPPIVEEWNSRAGGNQRNRGNRLQDNRQFRGRDNRWGWPSDNRSNQWHGRSWGNNYPQHRQEPYYPQQYGHYGYNQRPPYGYY
What is the function of this protein?
Component of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs.
What are the official names of this protein?
RNA guanine-N7 methyltransferase-activating subunit-like protein.
What is the protein family that this protein belongs to?
Belongs to the RAM family.
Protein: SURE_BRUSU
Sequence: MRILLTNDDGIHAEGLAVLERIARKLSDDVWVVAPETDQSGLAHSLTLSEPLRLRQIDARHFALRGTPTDCVIMGVRHVLPGAPDLVLSGVNSGANMADDVTYSGTVAGAMEGTLLGVRAIALSQEYEYAGDRRIVPWETAEAHAPELIGRLMEAGWPEGVLLNLNFPNCAPEEVKGVRVTAQGKLSHDARLDERRDGRGFPYFWLHFGRGKAPVADDSDIAAIRSGCISVTPLHLDLTAHKVRAELGAALGVEA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJJJ_ECOLI
Sequence: MSELTDLLLQGPRSAPELRQRLAISQATFSRLVAREDRVIRFGKARATRYALLRPYRGIERIPVWRVDDTGKAHKFADIRLCWPQGSCLVTGADGDEQWFDGLPWYLTDLRPQGFLGRAWGRKLAAQLNLTDDIRLWQEEDVLYALTVFNGEYTGGWLVGEGNYQRWITAQHPAEIPLDQKLTHYEQLASDALAGEIVGSSAGGEQPKFTYYAQTPSGNKHVLVKFTVPQQTAVSQRWGDLLIAESIAAQILRDGGIHAIESTVLVTSNRQVFLEAERFDCKGNDGRLPIVSLEAVQSEFISSPGSWPQAMRRLCEQQLVTHQSVAQTEVIWAFGRLIANSDMHAGNLSFYLSEPPFALTPVYDMLPMVYAPNSAGMLRDAAIEVKFDLNVSKSAWLTAIPLAQQFWQTVARDPRISEAFRHIAQEMPEKIRQIEEKVARMGG
What is the function of this protein?
Toxic when overexpressed in E. coli, leading to long filamentous cells.  The toxic effect is neutralized by non-cognate antitoxin HipB (PubMed:28430938).  Does not seem to inhibit DNA, RNA or protein synthesis, and unlike paralogous toxin HipA its toxic activity is not counteracted by overexpression of GltX (PubMed:28430938).  Binds DNA (PubMed:28430938).  Might be a protein kinase (By similarity).
What are the official names of this protein?
Toxin YjjJ, Putative DNA-binding transcriptional regulator YjjJ, Putative serine/threonine kinase toxin YjjJ.
What is the protein family that this protein belongs to?
Belongs to the HipA Ser/Thr kinase family.
Protein: CAHS3_HYPEX
Sequence: MSNYQQESSYQYSDRSNNGQQQEQQEKKEVEHSSYTHTDVKVNMPNLIAPFISSSAGLAQELVGEGFQASVSRITGASGELTVIDTEAETEEARRDMEAKAREQELLSRQFEKELERKTEAYRKQQEVETEKIRKELEKQHLRDVEFRKELMEQTIENQKRQIDLEARYAKKELERERNKVKRVLERSKFHTDIQVNMEAAAGSTHSGSSSVAVSESEKFQTNN
What is the function of this protein?
CAHS proteins are cytosolic heat soluble proteins that seem to contribute to the anhydrobiosis in tardigrades, but their specific mechanisms are yet to be identified (PubMed:28306513, PubMed:33545053).  It is possible that protection during anhydrobiosis might occur via the stabilization of vitrifying small molecules such as sugars, but not via the direct glass transition of CAHS proteins themselves (Probable).
What are the official names of this protein?
Cytosolic-abundant heat soluble protein 77580, CAHS 77580, Tardigrade-specific intrinsically disordered protein CAHS 77580, TDP CAHS 77580.
What is the protein family that this protein belongs to?
Belongs to the Cytosolic-abundant heat soluble protein (CAHS) family.