PharMolix/UniProtQA huggingface dataset:
Protein: TIG_SALTY
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFVDAIIKEKINPAGAPNYVPGEYKVGEDFTYSVEFEVYPEVELTGLESIEVEKPVVEVTDADVDVMLDTLRKQQATWKEKDGAADAEDRVTIDFTGSVDGEEFEGGKATDFVLAMGQGRMIPGFEDGVKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFVINLKKVEERELPELTEEFIKRFGVEDGSVAGLRAEVRKNMERELKGAVRNRVKSQAIEGLVKANDIDVPSALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVSEKATSFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: SURE_METM5
Sequence: MTMEILLVNDDGIYSNGLLALKNVISEEFDANITVVAPTNQQSGIGRAISLFEPLRITKTKLADCSEGYAVSGTPTDCVVLGVHQVLKKVPDYVISGINIGENLGTEITTSGTLGAAFEGAHHGAKALACSLQVTTDHLKFKEGESPIDFMNTARIVRNVFKKFIDDEFPCDVININVPDNATENTPVEITKLAKKMYSMHVEERIDPRSRSYYWLDGYPIMDEEDGTDVYAVRNKRNVSVTPLTLDNTAKNLDEFKEKYAKKF
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_GLAP5
Sequence: MTTQNFLAEIGTEELPPKALKKLATAFAENVEAELNQAGLSFDKVEWFAAPRRLAVKVLGLATAQPSKEVEKRGPAVSAAFDAEGKPTKAAEGWAKGCGITVEQAERIATDKGEWLVHRAVIEGQPTKNLLVGIISQALAKLPIPKTMRWGDKTEQFVRPVHTVTLLLGDELIEGEILGVASGTTVRGHRFLGEREFQISHADQYPALLKEKGSVVADFNERKALILAKAQEKATALGGVADIEEDLLDEVTSLVEYPNVLAAKFEERFLAVPAEALVYTMKGDQKYFPIYDKDGKLLPHFIFVSNINPEDPSKIIEGNEKVVRPRLTDAEFFFKTDLKQRLEDQLPRLETVLFQQQLGTLRDKTARIEQLAGEIAKQIGADETKAKRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEDEEVAVALNEQYMPRFAGDELPKSLVASSVALADKFDTLTGIFGIGQAPKGSADPFALRRAALGALRIIVEKNLPLDLSDLVATSAKLFGDKLTNSNVVEEVVDFMLGRFRAWYQDEGIAVDVIQAVLARRPTRPADFDARVRAVSHFRTLDSAEALAAANKRVSNILAKVEGKISSEIDRTLLVEAEEKALAEQVITLQAELVPLFEKGEYQTALDRLAGLREVVDNFFDKVMVNAEDPKLRQNRQAILNNLRNLFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_GEOKA
Sequence: MASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERIELLREVTRTLPNVHVEAFHGLLVDYARSKKANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMTNSQYAFLSSSIVKEVAKYNGDISELVPPVVEQALKRKFASTAAD
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YSY6_YEAST
Sequence: MAVQTPRQRLANAKFNKNNEKYRKYGKKKEGKTEKTAPVISKTWLGILLFLLVGGGVLQLISYIL
What is the function of this protein?
May interact with target proteins during translocation into the lumen of the endoplasmic reticulum.  May protect unfolded target proteins against degradation and facilitate correct glycosylation (Potential).
What are the official names of this protein?
Protein YSY6.
What is the protein family that this protein belongs to?
Belongs to the RAMP4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: HSDL1_HUMAN
Sequence: MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDFYSLIRLHFIPRLGSRADLIKQYGRWAVVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHRCSWLVPSPKVYAHHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANILNRSLRKEALSCTA
What are the official names of this protein?
Inactive hydroxysteroid dehydrogenase-like protein 1, Short chain dehydrogenase/reductase family 12C member 3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL29_BORPD
Sequence: MKASELRSKDAAELGQELESLLKAQFGLRMQKATQQLANTSQLRNVRRDIARVRTLLTEKAGK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: K1C40_HUMAN
Sequence: MTSDCSSTHCSPESCGTASGCAPASSCSVETACLPGTCATSRCQTPSFLSRSRGLTGCLLPCYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYLEKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQLDNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLKKNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQTEELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQLAQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSPCSTTCTSSNTCEPCSAYVICTVENCCL
What is the function of this protein?
May play a role in late hair differentiation.
What are the official names of this protein?
Keratin, type I cytoskeletal 40, Cytokeratin-40, CK-40, Keratin-40, K40, Type I hair keratin Ka36.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: DPOLN_MOUSE
Sequence: MENYEACVGFDVCEIPLSAVAQKIMSAMRSGDFMDSRNEGESTNTSKVAKKSSVHYSVLAEHEETQSLGTKNPESLITQTPRGSIELCPQPSITKLTCQLSAGQVQNSISSLGLSSYLIPQCDQEASVLPNMEHKRQHFLKENIGKEDKDNSSLKRKYITCSKSSEKASKHTALEKDTDGTESWPNSRDTRALGERLCDVRYLGDLAKAQLMDALKQAAALVVTLMYKDGSTQLSAKEALTCTVKGIVVLLKSHVGNSTLTLPAHGGALEKDFISEDHCVYIHTEHSPFWDPKQEAHSLFVRNILFWTLRCKCPVVCFNAKDFVRTVLQLYGEDGSWKHVADFVGLDPRVAAWLIDPSDTAPSFEDLVAKHLEKSITVKPSSTFREASRNTLSQNVFMNLKILYDLTMDLCSKLKAYGLWQLFCTLELPLIPILAVMENHKIPVDKEEMERTSALLGARLKELEQEAHFVAGEQFLIMSNNQLREILFGKLKLHLLSQRKHLPRTGLQNQLSTSEAMLNSLQDLHPLPKLILEYRQVHKIKSTFIDGLLAYMKKGSISSTWNQTGTVTGRLSAKHPNIQGISKHPIKISKPWNFKGKEEETVTISPRTLFVSSEGHTFLAADFSQIELRILAHLSGDPELLKLFQESERDDVFSTLTSQWKDIPIERVTHMDREQTKKVVYSVVYGAGKERLAACLGVTVLEATHFLERFLQKYKKIKDFAQTVIGQCHSAGYVTSILGRRRPLPRICAQDQQLRAQAERQAVNFVVQGSAADLCKLAMIRISTAVATSPTLTARLVAQIHDELLFEVEDTQVPEFAALVRRIMESLQQVQTLELQLQVPLKVNLSVGRSWGHLTPLQEILGSA
What is the function of this protein?
DNA polymerase with very low fidelity that catalyzes considerable misincorporation by inserting dTTP opposite a G template, and dGTP opposite a T template.  Is the least accurate of the DNA polymerase A family (i. e.  POLG, POLN and POLQ).  Can perform accurate translesion DNA synthesis (TLS) past a 5S-thymine glycol.  Can perform efficient strand displacement past a nick or a gap and gives rise to an amount of product similar to that on non-damaged template.  Has no exonuclease activity.  Error-prone DNA polymerase that preferentially misincorporates dT regardless of template sequence.  May play a role in TLS during interstrand cross-link (ICL) repair.  May be involved in TLS when genomic replication is blocked by extremely large major groove DNA lesions.  May function in the bypass of some DNA-protein and DNA-DNA cross-links.  May have a role in cellular tolerance to DNA cross-linking agents.  Involved in the repair of DNA cross-links and double-strand break (DSB) resistance.  Participates in FANCD2-mediated repair.  Forms a complex with HELQ helicase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links.
What are the official names of this protein?
DNA polymerase nu.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUB_CROS8
Sequence: MSRPRRRGRDVHGVLLLDKPQGLSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGTVVEERPVTFSEQQLQDALESFRGDTLQVPTMFSALKYQGKPLYEYARQGIEVPREARPITVYELLFIRHEGDELELEVHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLTVSKYPVERMVTLEQLNALLEEAQTRDIAPSELLDPLLMPMDSPAADYPVVNLPLTSSVYFKNGNPVRTTGAPSEGLVRVTEGEAQKFLGMGEIDSEGRVAPRRLVVEYPV
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: DEXHD_ARATH
Sequence: MTNLGGGGAEEQARLKQYGYKVNSSLVLNSDERRRDTHESSGEPESLRGRIDPKSFGDRVVRGRPHELDERLNKSKKKKERCDDLVSARESKRVRLREVSVLNDTEDGVYQPKTKETRVAFEIMLGLIQQQLGGQPLDIVCGAADEILAVLKNESVKNHEKKVEIEKLLNVITDQVFSQFVSIGKLITDYEEGGDSLSGKASEDGGLDYDIGVALECEEDDDESDLDMVQDEKDEEDEDVVELNKTGVVQVGVAINGEDARQAKEDTSLNVLDIDAYWLQRKISQEYEQKIDAQECQELAEELLKILAEGNDRDVEIKLLEHLQFEKFSLVKFLLQNRLKVVWCTRLARGRDQEERNQIEEEMLGLGSELAAIVKELHAKRATAKEREEKREKDIKEEAQHLMDDDSGVDGDRGMRDVDDLDLENGWLKGQRQVMDLESLAFNQGGFTRENNKCELPDRSFRIRGKEFDEVHVPWVSKKFDSNEKLVKISDLPEWAQPAFRGMQQLNRVQSKVYGTALFKADNILLCAPTGAGKTNVAVLTILHQLGLNMNPGGTFNHGNYKIVYVAPMKALVAEVVDSLSQRLKDFGVTVKELSGDQSLTGQEIKETQIIVTTPEKWDIITRKSGDRTYTQLVRLLIIDEIHLLDDNRGPVLESIVARTLRQIESTKEHIRLVGLSATLPNCDDVASFLRVDLKNGLFIFDRSYRPVPLGQQYIGINVKKPLRRFQLMNDICYQKVVAVAGKHQVLIFVHSRKETAKTARAIRDTAMANDTLSRFLKEDSQSREILKCLAGLLKNNDLKELLPYGFAIHHAGLTRTDREIVENQFRWGNLQVLISTATLAWGVNLPAHTVIIKGTQVYNPERGEWMELSPLDVMQMIGRAGRPQYDQQGEGIIITGYSKLQYYLRLMNEQLPIESQFISKLADQLNAEIVLGTIQNAREACHWLGYTYLYVRMVRNPTLYGVSPDALAKDLLLEERRADLIHSAATILDKNNLIKYDRKSGHFQVTDLGRIASYYYISHGTIAAYNENLKPTMNDIELCRLFSLSEEFKYVTVRQDEKMELAKLLDRVPIPVKETLEDPSAKINVLLQVYISKLKLEGLSLTSDMVYITQSAGRLLRAIFEIVLKRGWAQLSQKALNLSKMVGKRMWSVQTPLWQFPGIPKEILMKLEKNDLVWERYYDLSSQELGELICNPKMGRPLHKYIHQFPKLKLAAHVQPISRSVLQVELTVTPDFHWDDKANKYVEPFWIIVEDNDGEKILHHEYFLFKKRVIDEDHTLNFTVPISEPIPPQYFIRVVSDKWLDSPTVLPVSFRHLILPEKYPPPTELLDLQPLPVMALRNPSYETLYQDFKHFNPVQTQVFTVLYNTSDNVVVAAPTGSGKTICAEFAILRNHLEGPDSAMRVVYIAPLEAIAKEQFRDWEKKFGKGLGLRVVELTGETLLDLKLLEKGQIIISTPEKWDALSRRWKQRKYIQQVSLFIVDELHLIGGQGGQVLEVIVSRMRYISSQVGNKIRIVALSTSLANAKDLGEWIGASSCGVFNFPPNVRPVPLEIHIHGVDILSFEARMQAMTKPTYTAIVQHAKNKKPAIVFVPTRKHVRLTAVDLIAYSHMDNMKSPDFLLGNLEELEPFLIQICEETLKETLRHGIGYLHEGLSNLDQEIVTQLFEAGRIQVCVMSSSLCWGTPLKAHLVVVMGTHFYDGRENSHSDYPISNLLQMMGRGSRPLLDDAGKCVIFCHAPRKEYYKKFLYEALPVESHLQHFLHDNFNAEVVARVIENKQDAVDYLTWSFMYRRLPQNPNYYNLLGVSHRHLSDHLSELVENTLSDLEVSKCIEIDNELDLSPLNLGMIASYYYINYTTIERFSSLLASKTKMKGLLEILTSASEYDLIPIRPGEEDAVRRLINHQRFSFQNPRCTDPRVKTSALLQAHFSRQKISGNLVMDQCEVLLSATRLLQAMVDVISSNGCLNLALLAMEVSQMVTQGMWDRDSMLLQLPHFTKDLAKRCHENPGNNIETIFDLVEMEDDKRQELLQMSDAQLLDIARFCNRFPNIDLTYEIVGSNEVSPGKDITLQVLLERDMEGRTEVGPVDAPRYPKTKEEGWWLVVGEAKTNQLMAIKRISLQRKAQVKLEFAVPTETGEKSYTLYFMCDSYLGCDQEYSFTVDVKDSDAADHMEE
What is the function of this protein?
RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes.  Involved in spliceosome assembly, activation and disassembly.
What are the official names of this protein?
DExH-box ATP-dependent RNA helicase DExH13, BRR2 homolog B, AtBRR2B, Pre-mRNA-splicing helicase BRR2B.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSPA_SAGOE
Sequence: MNVLLGGLVIFATFVTLCNGSCYLMPNKMVPGDSTKECTDLKGNKHPLNSRWKTENCDECDCLEKEISCCSLVAIPVGYDQDNCQKIFKQEDCKYIVVEKKDPNKTCEVTQWI
What are the official names of this protein?
Beta-microseminoprotein A1, msp-A1.
What is the protein family that this protein belongs to?
Belongs to the beta-microseminoprotein family.
What are the subcellular locations of this protein?
Secreted. Note=Sperm surface.
Protein: CATA_DICDI
Sequence: MSAPVLTTSSGSPIDNNLNSMTAGVNGPILIQDFTLIDKLAHFDRERIPERVVHAKGAGAHGYFEVPSSDVPKWCKAKFLNKVGKRTPIFTRFSTVGGEKGSSDSERDPRGFAVKFYTEEGNFDMVGNNTPVFFIRDPSKFPDFIHTQKRNPQTNCKDPNMFWDFLGQTPESTHQVSILFSDRGTPKSYRHMHGFSSHTLKFVNAQGKPYWVKLHFTSETGIQNYTAEEAAKMSMNDPDSATRDLFETIAKGGEPAWKVSIQLMEFEDALKYRFNPFDVTKIWSHKDYPLIQIGRMVLNRNPENYFAEVEQAAFSPSHMVPGIEPSPDKMLQGRLFSYPDTHRHRLGVNYQQIPVNCPFAVKGGVKNYQRDGFMAVNGNGGKGPNYQPNSFGGPEPHPEFAQHKFDVSGFAARQPYNHPNDDFVQPGDLYRLMSEDAKSRFVSNLVGHMSGVTIKEIQVRAVSNFYKADKDLGARLCKGLGIDVNDVIKFAARSNL
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase-A.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: JIP1_HUMAN
Sequence: MAERESGGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQCKDTLSLRPPRAGLLSAGGGGAGSRLQAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQSGPAPTTDRGTSTDSPCRRSTATQMAPPGGPPAAPPGGRGHSHRDRIHYQADVRLEATEEIYLTPVQRPPDAAEPTSAFLPPTESRMSVSSDPDPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASVSSPYESAIGEEYEEAPRPQPPACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE
What is the function of this protein?
The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module.  Required for JNK activation in response to excitotoxic stress.  Cytoplasmic MAPK8IP1 causes inhibition of JNK-regulated activity by retaining JNK in the cytoplasm and inhibiting JNK phosphorylation of c-Jun.  May also participate in ApoER2-specific reelin signaling.  Directly, or indirectly, regulates GLUT2 gene expression and beta-cell function.  Appears to have a role in cell signaling in mature and developing nerve terminals.  May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins.  Functions as an anti-apoptotic protein and whose level seems to influence the beta-cell death or survival response.  Acts as a scaffold protein that coordinates with SH3RF1 in organizing different components of the JNK pathway, including RAC1 or RAC2, MAP3K11/MLK3 or MAP3K7/TAK1, MAP2K7/MKK7, MAPK8/JNK1 and/or MAPK9/JNK2 into a functional multiprotein complex to ensure the effective activation of the JNK signaling pathway.  Regulates the activation of MAPK8/JNK1 and differentiation of CD8(+) T-cells.
What are the official names of this protein?
C-Jun-amino-terminal kinase-interacting protein 1, JIP-1, JNK-interacting protein 1, Islet-brain 1, IB-1, JNK MAP kinase scaffold protein 1, Mitogen-activated protein kinase 8-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the JIP scaffold family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Endoplasmic reticulum membrane. Mitochondrion membrane. Note=Accumulates in cell surface projections. Under certain stress conditions, translocates to the perinuclear region of neurons. In insulin-secreting cells, detected in both the cytoplasm and nucleus (By similarity).
Protein: Y334_ARCFU
Sequence: MKVGVKYCGGCNPEYRREDVEDVLRKHFTIFYSEDADVLVLINGCKKACLLEEVNHPKVVSVDSPVSEEELLRRVLKAMRG
What are the official names of this protein?
Uncharacterized protein AF_0334.
Protein: HBP1_MOUSE
Sequence: MVWEVKTNQMPNAVQKLLLVMDKRAPGMSDSLELLQCNENLPSSPGYNSCDEHMELDDLPELQAVQSDPTQSAIYQLSSDVSHQEYPRSSWSQNTSDIPENTHREDEVDWLTELANIATSPQSPLMQCSFYNRSSPVHIIATSKSLHSYARPPPVSSSSKSGPAFPHDHWKEETPVRHERANSESESGIFCMSSLSDDDDLGWCNSWPSTIWHCFLKGTRLCFHKESNKEWQDVEDFARAASCDNEEEIQMGTHKGYGSDGLKLLSHEESVSFGESVLKLTFDPGTVEDGLLTVECKLDHPFYVKNKGWSSFYPSLTVVQHGIPCCEIHIGDVCLPPGHPDAINFDDSGVFDTFKSYDFTPMDSSAVYVLSSMARQRRASLSCGGGPGTGQEFSGSEFSKSCGSPGSSQLSSSSLYAKAVKSHSSGTVSATSPNKCKRPMNAFMLFAKKYRVEYTQMYPGKDNRAISVILGDRWKKMKNEERRMYTLEAKALAEEQKRLNPDCWKRKRTNSGSQQH
What is the function of this protein?
Transcriptional repressor that binds to the promoter region of target genes.  Plays a role in the regulation of the cell cycle and of the Wnt pathway.  Binds preferentially to the sequence 5'-TTCATTCATTCA-3'.  Binding to the histone H1. 0 promoter is enhanced by interaction with RB1.  Disrupts the interaction between DNA and TCF4 (By similarity).
What are the official names of this protein?
HMG box-containing protein 1, HMG box transcription factor 1, High mobility group box transcription factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: FB6_ARATH
Sequence: MACVKFPWELMEEILYRVPSLSLSRFKTVSKEWNTLLNDKTFIKKHLALVRPQFRLWTNSKVYSVDVSLNDDPNIELRELPLDIPYVIDHRTTNFLPCNDLLFCASWWSNKAVVWNPSLRQTRLIKSGEEHFRFGGIGYDSGRPGKGYHIFGHSHSRLSVNGNTSKFIKRFYITKFESNAWKCIDDVSLGENSIGGDSLDNNNVSLNGNLYWTTNSYDTDEYLIQSFDFSKEIFKIFCVLPRKKDSSDIPVLSVFRGDRLSVLHKFKGTNNMEIWVTKNKINESVKAVVWMMFMTVSIPIYKDSKPSYFINDIYEKRLVMCCSDENGKACVYIVKDQARKKIQLGFHVSEFSHCFYDPSLIPIPSETSGQKISNS
What are the official names of this protein?
Putative F-box protein At1g12190.
Protein: DEN10_MOUSE
Sequence: MAAVVAMDTQLMLGVGLIEKDSNGEALWVWCYPSTTASLRNLLLRKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKYAAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIKDIVSQFGMETVILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWTILHSYMHLHAEELEGLQMCTGYIAGFVELEVSNRPDLYDVFVNLADSEITIAPLAKEAMTMGKLHKEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEVSDDGGKVILNVEALKQQRFPPATENFLYHLAAAEQMLKV
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) regulating homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion, possibly through activating Rab proteins such as RAB27A and RAB27B.  Seems to promote the exchange of GDP to GTP, converting inactive GDP-bound RAB27A and RAB27B into their active GTP-bound form.
What are the official names of this protein?
DENN domain-containing protein 10, Protein FAM45A.
What is the protein family that this protein belongs to?
Belongs to the DENND10 family.
What are the subcellular locations of this protein?
Late endosome.
Protein: MUTH_SHEB2
Sequence: MNRIIPPENLPELLERAHMMAGVSLAQIAAQRGLSVPKDLKRDKGWVGQLIEMELGATAGSKPEQDFLHLGVELKTIPIDSQGRPLETTYVCVAPLSNIQGLTWQNSLVSHKLQRVLWVPVEGERHIPVGERRIGTPILWEPDPQELQLLQQDWEEIMELIALGKVEKLTARHGEVLQLRPKAANSKALTQSIAEDGSLKMTNPRGFYLKTSFTAMILNKVFG
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_POLAQ
Sequence: MRDQQIIAAELENLGYTLVEIEREAGGLLRVTIENPDYERLISVLDCEKVSHQLSYALPVENIPYERLEISSPGLDRPVKSAADFERFTGMEVDLKLRVAAGNRKNFRGVLQGLLSGELNSPDAKFGLLFEGADGAESQLEFSLAEVDKTRLVPVIDFKGRKS
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1AT_CALCN
Sequence: MPSSISWGLLLLAGLCCLAPGSLAGDAQETDASKDDHEHPACHKIAPNLAEFAFDLYRVLARQSNTTNIFFSPVSVATALAALSLGTKGDTHTQILEGLDFNLTEMAETDIHQGFQHLLQTLNRPNNQLQLTTGNGLFIDQSLKLADKFLEDVKNLYHSEAFSTNFTDSEEAKKQINGYVEKGTQGKIVDAVKTLDKNTVFALVNYIFFKGKWEKPFEVEHTTEGDFHVDQATTVKVPMMNRLGRFDLLYCTTLASWVLQMDYLGNATAIFLLPDEGKLQHLEDTITKEILSKFLKNRHTRTVNLYFPKLSITGTYDLRSVLSTLGITKVFSNEADLSGVTEEAPLKLSKGVHKAVLTIDERGTEAAGVTVLEAIPMSLPPDVRFDRPFLIIIYEHYTKSPLFVGKVVNPTQ
What is the function of this protein?
Inhibitor of serine proteases.
What are the official names of this protein?
Alpha-1-antiproteinase, Alpha-1-antitrypsin, Alpha-1-proteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF_PSEMY
Sequence: MAILNILEFPDPRLRTIAKPVDVVDDSIRQLVDDMFETMYDAPGIGLAATQVNVHKRVVVMDLSEDKSEPRVFINPEFESLTDEMDQYQEGCLSVPGFYENVDRPQKVKIKALDRDGQPFELIAEGLLAVCIQHECDHLNGKLFVDYLSNLKRDRIKKKLEKQHRQRA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: ENGB_STRZT
Sequence: MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINTMLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGRMIEEYLTTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESAIKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: SYK_THEAC
Sequence: MISLFWADALVKDLSGPQRVSTGISPSGPIHVGNMREILTGDILFKAITKRGLESDFIYLCDDMDPLRKVYPFLSKDYERYVGQPLKNIPAPQGAGKYSDYYLEPFVRVMKEANIPARVIKTSDLYESGMLAQACDIAINNREKIKDILETVSGRKIEGDFYPYEPLCEKCGRISTTHVISYSYPYAEYACKCGHHGFADIRKAEGKMPWRVEWPAKWFALKVTVEPFGKDHGAPGGSYDTGRRIAREVFGIEPPVPLMYERIILKGKGAMHSSTGLAIAASEIMEVIPPDLLRYMIARVNPGRHIDFDPGMGILALSDELEKLQDAYFENRASLDEDQAAMVEYSLVNKDRKPYPVDFRHLVTLVQIYRTEDEILRAVKKGQPSDFIEADFRKEIEYARRWLERYAPESVKFRILPVDQKIELSDSDLAILSDFLNGIEDMPWNSESIHDRIYEISQKFKTNPESVFTLFYRVFIGKDRGPRLGYFLFNLGKDFVRERIRNVIRDH
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPT_STRU0
Sequence: MKLLEERIIKDGNVLGENILKVDSFLTHQVDYHLMRDIGKVFAESYADAGITKVVTIEASGIAPAVYVAEALKVPMIFAKKHKNITMTEGILTAEVYSFTKQVTSTVSIASKFLSKDDKVLIIDDFLANGQAAKGLIEIIQQAGASVEGVGIVIEKSFQDGRQLLENMGVKVTSLARIKNFENGRLNFMEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_CORDI
Sequence: MNIVLASSSPSRLSILRSAGVEPLVCPADVDEDALLDSLVGRSPADKVAALAQAKAEAIAGDYPDDVVIGGDSMLLLDGALQGKPHTVDKTIERWKQQRGKTAELITGHCVITPRGRHVETSTTTVTFAHADDADIEAYARTGEPLQCAGAFTLEAIGGWFIDSITGDPSSVIGLSLPVVRRALYAAGYNVSEFWNNN
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.