PharMolix/UniProtQA huggingface dataset:
Protein: Y1030_STRPD
Sequence: MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEKISILTSIDNRE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein MGAS10270_Spy1030.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: APOE_DICSS
Sequence: MKVLWPALVVTLLAGCRADVEPGPEVQLGKEWATWQASQPWEQALGRFWNYLRWVQTLSEQVQEELLSSQVTEELTALMDDTMKEVKACKSELEEQLGPVAEETKARVSKELQAAQARLGADMEEVRNRLAQYRGELQAMVGQSTEELRGRLNAHLRKLRKRLLRDAEDLQQRLAVYQAGIREGAERSVNTLREHLGPLAEQAATMHTLVSKPLQERAEAWAQRLRGRLEKAGFPVGDRLDEVREQVQEVRAKVEEQANQVRLQAEAFQGRLKSWFEPLVQDMQQKWAELVEKVQLALRAVPTSVPSEKQ
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: NRDI_AGRFC
Sequence: MGLIVYYSSRSENTHRFLLKLERRLFRLPLGAEEDVPQVSEPYVLVTPTYGGGGTKGAVPKPVIRFLNEPSNRNLIRGVIAAGNTNFGAAFASAGDIVSRKCAVPFLYRFELLGTEEDVANVKHGLERFWTR
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: HIS2_BACSU
Sequence: MKQADELRFNEDGLIPAIVQDAASKEVLTLAYMNKESYEKTLETKETWFYSRSRQALWHKGETSGNTQAVKGIRYDCDQDALLVLVEPSGPACHTGSYSCFTKEQTEEQAADRFGIMNELERVIAERQAEMPEGAYTTYLFREGVDKILKKVGEEASEVIIAAKNRDHEELKWEAADLLYHLLVLLREQSLPLDDVLDVLKKRHSEIEE
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_CHLTR
Sequence: MSRLKKLYTEEIRKTLQDKFQYENVMQIPVLKKIVISMGLAEAAKDKNLFQAHLEELAVISSQKPLVTRARNSIAGFKLREGQGIGAKVTLRGIRMYDFMDRFCNIVSPRIRDFRGFSCKGDGRGCYSFGLDDQQIFPEVDLDRVKRSQGMNITWVTTAQTDAECLTLLECMGLRFKKAQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TRMB_CHLMU
Sequence: MKPQDLKLPYFWEDRCPKIENHVFYVPSYYPKYEEFVMPSWQNLFANEGPVCCELCSGNGDWVVEQALKDTSINWIAVEKRFDRVRKIWSKMSNHKVNNLLIVCGEAQTFFTHYVTDASFQKIVVNFPDPWPKFRHRKHRLFQDVFVQDMVRVLVEGGQLTLVTDDHTYLTNSIQVMLNYLSPGMQDPYYVNVKDNYGGSWFENLWRSKGEKIFCTEFVKRVGI
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RL31_ACTSZ
Sequence: MKQGIHPEYKEITATCSCGNVIKTRSTLGKDINLDVCGNCHPFYTGKQRVVDTGGRVERFNKRFSIPGTKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: EAP_BOVIN
Sequence: MRLHHLLLTLLFLVLSAGSGFTQGISNPLSCRLNRGICVPIRCPGNLRQIGTCFTPSVKCCRWR
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Enteric beta-defensin.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family. LAP/TAP subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: COAD_XANOP
Sequence: MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALSLERRVALAQEALAAHANVEVRGFDTLLAHFVRQMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPSEQYSFISSSLVREIARLGGDVSGFVPASVVEALRQVRESRAQA
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y302_SHESH
Sequence: MIKKIDGTQLHTFVLSTWHFMIHLKQRLAEDQINIRAGHLAYVTLLSLVPMVAVTMSMLSAFPVFSGIRGQIEGFIYNNFLPAAGDTVQVYINEFVSNASKGTAVGIAALMVVAIMLISAIDKALNNIWRTTEKRSMVVSFSMYWMVLTLGPVLMGASLVATSYVVSLKVFNGSDLSGVVPVLVERLPMFFSVATFLLIYMVVPNIKVKFFHALLGAIVAALLFEFGKKGFAIYLTKFPTYEAIYGALATIPILFMWVYLSWIIVLLGAEITAAMPEYLDKRQSGKDEESEKKAEAHDPQISFSISTAVNESKKENRQ
What are the official names of this protein?
UPF0761 membrane protein Ssed_0302.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: G1PDH_METHJ
Sequence: MSTDPVQVLQPDGFNKSRWTQLPRDVLIGHQAIMQLPDIIADIKPGRSVLLISGGTTREVAGNTVADILKDQYEVRRFVAGKLDADTLEACSQASSSADFLIGVGGGRVIDCAKIVSYKQGKPFISVPTAASHDGIISGRATLPTETGSVSVGAHPPIAVVADTGIISQAPHRLMASGCADVISNYTAILDWELAHRLRGEQISEYAIALSKMTAEILVKDANLIKPGQEEAAWIVVKALVSSGVSMAIAGSSRPASGGEHKFGHALERLMPGAALHGEACGIGSIMTMYLHGGDWREIRSSLARIGAPTTPRELNIPDEVIVEALMKARDIRPERFTILDMGLTRESAEHLVQMLYEE
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJL_SHIBS
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTAHSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: THIO_ECHGR
Sequence: MSVEAVVKQVDGDALEAAIKGDKLLVCDFFATWCGPCKSLAPKLDAMAKENEKVIFVKLDVDECQDVAEKYRVTAMPTLIVFKNGCEIGHVVGANEAGIRELIQANA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: ATPF_STRP6
Sequence: MSITFGELVGNFILVTGSVIVLLLLIKKFAWGAIESILQTRSQQISRDIDQAEQSRLSAQQLETKSQANLDASRSQASKIISDAKEIGQLQGDKLVAEATDEAKRLKEKALTDIEQSKSDAISAVKTEMSDLTVLLAEKIMGANLDKTAQSQLIDSYLDDLGEA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: VF151_ASFP4
Sequence: MMALLHKEKLIECIENEVLSGGTVLLLVKNIVVSEISYMGDSYKYFTFNANHDLKSKEDLKGATSKNIAKMIYNWIIKNPQNNKIWSGEPRTQIYFENDLYHTNYNHECIKDFWNVSTSVGPCIFNDRSIWCTKCTSFYPFTNIMSPNIFQ
What is the function of this protein?
May participate in a redox cascade for the formation of disulfide bonds in viral proteins.
What are the official names of this protein?
Protein A151R, pA151R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus A151R family.
Protein: CBID_VARPS
Sequence: MMDKGAPRGTRTGFTTGACSAAAARAAVIGLVTGQVPDHVECLLPNGDLVRFAVHDGRVDSASAHAMVIKDAGDDPDCTDKAHLTADVRLLPDLAGQVVLAGGTGVGTVTMPGLGLAVGGPAINPVPRRNIEANVRAVGAALLDEVGLEVAISVPQGEEMAKKTLNARLGILGGISILGTTGIVKPYSTAAYRASVVQGVQVAGTLGHGVVVLTTGGRTEKFVMAEMPELPEPAFVQMGDFLRYAMGAAVKAGIRKVVIGGMVGKLTKIAQGETITHAGRAEVDTGLLADLAAGLGAPPDVCDAIRGNETARYAGERMDALGLGTAFHTALAQRVIQTLRTRYPDQFELKVLVCDFEGRKIAEAP
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: CAN12_HUMAN
Sequence: MASSSGRVTIQLVDEEAGVGAGRLQLFRGQSYEAIRAACLDSGILFRDPYFPAGPDALGYDQLGPDSEKAKGVKWMRPHEFCAEPKFICEDMSRTDVCQGSLGNCWFLAAAASLTLYPRLLRRVVPPGQDFQHGYAGVFHFQLWQFGRWMDVVVDDRLPVREGKLMFVRSEQRNEFWAPLLEKAYAKLHGSYEVMRGGHMNEAFVDFTGGVGEVLYLRQNSMGLFSALRHALAKESLVGATALSDRGEYRTEEGLVKGHAYSITGTHKVFLGFTKVRLLRLRNPWGCVEWTGAWSDSCPRWDTLPTECRDALLVKKEDGEFWMELRDFLLHFDTVQICSLSPEVLGPSPEGGGWHVHTFQGRWVRGFNSGGSQPNAETFWTNPQFRLTLLEPDEEDDEDEEGPWGGWGAAGARGPARGGRTPKCTVLLSLIQRNRRRLRAKGLTYLTVGFHVFQIPEELLGLWDSPRSHALLPRLLRADRSPLSARRDVTRRCCLRPGHYLVVPSTAHAGDEADFTLRVFSERRHTAVEIDDVISADLQSLQGPYLPLELGLEQLFQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQLLQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWMEVATFS
What is the function of this protein?
Calcium-regulated non-lysosomal thiol-protease.
What are the official names of this protein?
Calpain-12, Calcium-activated neutral proteinase 12, CANP 12.
What is the protein family that this protein belongs to?
Belongs to the peptidase C2 family.
Protein: HIS7_BRADU
Sequence: MRTATIKRKTKETDIEVTVNLDGTGVSNIATGIGFFDHMLDLLARHSRIDLTVKAVGDLHIDHHHTTEDTGIALGQAVKQALGTMAGITRYAGVHMPMDETLSRVVIDISGRPVLVFKVDFPRDKIGEFDTELVREWFQAFAMNASVTLHVETLYGDNSHHIAESCFKGLARALRAAVAIDPKAAGEIPSTKGSLGG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFY6_SCHPO
Sequence: MSLQLEKNLILELIPHFYSLGWMKFGSGNFCLKNNGYAICVKDRVQRDFITENDIVTFNLSNQSVTKDLVNWAYIFSWVLSNMDAVACIYSTSVAAVGASMYNEKFTTQSKEMIKGIPKGNPSAGYLCCFDTLEVPIIHNGDSKTILDELKKVIELYPQTCAVLIRGHGVIGWGATWEKSKTQMECYEYLFELDYKLKTL
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase-like protein.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: FCG3A_PAPAN
Sequence: MWQLLLPTALLLLVSAGMRAEDLPKAVVFLEPQWYRVLEKDSVTLKCQGAYSPEDNSTRWFHNESLISSQTSSYFIAAARVNNSGEYRCQTSLSTLSDPVQLEVHIGWLLLQAPRWVFKEEDSIHLRCHSWKNTLLHKVTYLQNGKGRKYFHQNSDFYIPKATLKDSGSYFCRGLIGSKNVSSETVNITITQDLAVSSISSFFPPGYQVSFCLVMVLLFAVDTGLYFSVKKSIPSSTSDWKDHKFKWSKDPQDK
What is the function of this protein?
Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG).  Optimally activated upon binding of clustered antigen-IgG complexes displayed on cell surfaces, triggers lysis of antibody-coated cells, a process known as antibody-dependent cellular cytotoxicity (ADCC).  Does not bind free monomeric IgG, thus avoiding inappropriate effector cell activation in the absence of antigenic trigger (By similarity).  Mediates IgG effector functions on natural killer (NK) cells.  Binds antigen-IgG complexes generated upon infection and triggers NK cell-dependent cytokine production and degranulation to limit viral load and propagation.  Involved in the generation of memory-like adaptive NK cells capable to produce high amounts of IFNG and to efficiently eliminate virus-infected cells via ADCC.  Regulates NK cell survival and proliferation, in particular by preventing NK cell progenitor apoptosis (By similarity).  Fc-binding subunit that associates with CD247 and/or FCER1G adapters to form functional signaling complexes.  Following the engagement of antigen-IgG complexes, triggers phosphorylation of immunoreceptor tyrosine-based activation motif (ITAM)-containing adapters with subsequent activation of phosphatidylinositol 3-kinase signaling and sustained elevation of intracellular calcium that ultimately drive NK cell activation.  The ITAM-dependent signaling coupled to receptor phosphorylation by PKC mediates robust intracellular calcium flux that leads to production of pro-inflammatory cytokines, whereas in the absence of receptor phosphorylation it mainly activates phosphatidylinositol 3-kinase signaling leading to cell degranulation.  Costimulates NK cells and trigger lysis of target cells independently of IgG binding (By similarity).  Mediates the antitumor activities of therapeutic antibodies.  Upon ligation on monocytes triggers TNFA-dependent ADCC of IgG-coated tumor cells (By similarity).  Mediates enhanced ADCC in response to afucosylated IgGs (By similarity).
What are the official names of this protein?
Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcgammaRIIIa.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Secreted. Note=Exists also as a soluble receptor.
Protein: SODF_MYCBO
Sequence: MAEYTLPDLDWDYGALEPHISGQINELHHSKHHATYVKGANDAVAKLEEARAKEDHSAILLNEKNLAFNLAGHVNHTIWWKNLSPNGGDKPTGELAAAIADAFGSFDKFRAQFHAAATTVQGSGWAALGWDTLGNKLLIFQVYDHQTNFPLGIVPLLLLDMWEHAFYLQYKNVKVDFAKAFWNVVNWADVQSRYAAATSQTKGLTFG
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOAE1_MYCTO
Sequence: MANVVAEGAYPYCRLTDQPLSVDEVLAAVSGPEQGGIVIFVGNVRDHNAGHDVTRLFYEAYPPMVIRTLMSIIGRCEDKAEGVRVAVAHRTGELQIGDAAVVIGASAPHRAEAFDAARMCIELLKQEVPIWKKEFSSTGAEWVGDRP
What is the function of this protein?
Converts molybdopterin precursor Z into molybdopterin.  This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group.  The sulfur is provided by MoaD (By similarity).
What are the official names of this protein?
Molybdopterin synthase catalytic subunit 1, MPT synthase subunit 2 1, Molybdenum cofactor biosynthesis protein E 1, Molybdopterin-converting factor large subunit 1, Molybdopterin-converting factor subunit 2 1.
What is the protein family that this protein belongs to?
Belongs to the MoaE family.
Protein: SSTT_HAEIN
Sequence: MNTSRLFSLLFQGGLVKRIAAGLVLGIVVALISAPLQETIGFNLAEKVGVLGTIFVKALRAVAPILIFFLVMAALANRKIGTKSNMKEIIVLYLLGTFLAAFVAVIAGFAFPTEVVLAAKEDSSSAPQAVGQVLLTLILNVVDDPLNAIFKANFIGVLAWSIGLGLALRHASDATKNVLSDFAEGVSKIVHVIISFAPFGVFGLVAETLSDKGLVALGGYVQLLAVLIGTMLFTAFVVNPILVYWKIRRNPYPLVWTCVRESGVTAFFTRSSAANIPVNIELAKRLNLDEETYSVSIPLGANINMAGAAITITILTLAAVHTLGLEVSFVSALLLSIVAALCACGASGVAGGSLLLIPLACSLFGISDDVAAQMIGVGFIIGILQDSTETALNSSTDVLFTAAVCMEEERKNAA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEG_BACCR
Sequence: MDFEQLKQDVIAYSKTIGIDKIGFASASPFEELKQRLIQQQQLNYQSGFEEPDIEKRTNPQLLLPGAKSIIAIALAYPSKLKNAPLSKRGERRGIFCRASWGQDYHLVLRDRLQKLEAYLIEKLPDIEVKSMVDTGELSDRAVSERAGIGWSGKNCSIITPEFGSYVYLGEMITNVPFPPDKPIEDQCGGCTKCIDICPTGALIQGGQLDSKKCIAFLTQTKGFLPEEYRDKIGNRIYGCDTCQTVCPKNKGMDFHNHPEMEPDPELVKPLLTPLLTISNRDFKEKYGIMSGSWRGKKPLQRNAILALAHFKEASAIPDLIGVMKDDPRPVLRGTAAWALGKIGGDGVGEAIEKAMEREKDEEVLHEMNRGLELLAQKKE
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_PSEPF
Sequence: MSQLPPAIFLMGPTAAGKTDLAIELTKVLPCELISVDSALVYRGMDIGTAKPSKELLAEFPHRLIDILDPAEAYSAADFRRDALEAMAEITARGKIPLLVGGTMLYYKALIEGLADMPAADPEVRAQIEEEAARLGWQALHDQLAAIDPESAARIHPNDPQRLSRALEVYRVSGQSMTELRLKQSVQSTEAAASGLQQLPYTVANLAIAPTNRQVLHERIKQRFTNMLEQGFIDEVVALRNRSDLHAGLPSIRAVGYRQVWDFLDGKLTSAEMQERGIIATRQLAKRQFTWLRSWKDLHWLDSLDCDNLPRALKYLGTISILS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PFDA_SULTO
Sequence: MSNEENQQKVVVSLEDLLAQADALKKYIDYLQKTYAELQDNIMSIDSSLQALKELQNSQELLMVGDKRGNVIFKVQGIDKAKVLVHLGLEYYAEVDPDFATKVLNDKKSELSNVLSNVEKELAKSLEAYKEIADILNQAQQQLQAQQNKGG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELT1_CAEEL
Sequence: MSRFGVFIIGVLFFMSVCDVLRTVSAEEHSHDENHVHEKDDFEAEFGDETDSQSFSQGTEEDHIEVREQSSFVKPTAVHHAKDLPTLRIFYCVSCGYKQAFDQFTTFAKEKYPNMPIEGANFAPVLWKAYVAQALSFVKMAVLVLVLGGINPFERFGLGYPQILQHAHGNKMSSCMLVFMLGNLVEQSLISTGAFEVYLGNEQIWSKIESGRVPSPQEFMQLIDAQLAVLGKAPVNTESFGEFQQTV
What is the function of this protein?
Probably has thioredoxin reductase-like oxidoreductase activity.  Plays a role in regulating the oxidative stress response, and odorant and pathogenic bacteria avoidance behavior (PubMed:28347729).
What are the official names of this protein?
Thioredoxin reductase-like selenoprotein T homolog selt-1.1.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. SELT subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: RSMG_LACLM
Sequence: MTPDEFLSALTDFDIKLSDKQIEQFERYFELLVEWNEKINLTAITEKNEVYLKHFYDSVAPILYGLITDQPVSILDIGAGAGFPSLPMKIIFPELEVTIIDSLNKRINFLSLLTEELGLENVTLLHGRAEDFGQDSNYRATFDFVTARAVARLSVLSEFTIPFLKKNGNLLSLKAAQFEEELTDAKKAIAILGGKFIKEIAYELPNGDERHIAVIEKKKETPKKYPRKAGTPAKSPIK
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDA2_YEASV
Sequence: MQIEIKDGRSDNSPLPERKLVTLIQESYDSLKDDNEINLSTESTSNLLIKLVLEKLEKHSSLYKYIASVTTLNIEGLNEENANFSLKNDIGASWESKKRWYIQL
What are the official names of this protein?
Topoisomerase I damage affected protein 2.
What is the protein family that this protein belongs to?
Belongs to the TDA2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Note=Concentrates at cytoplasmic punctate structures and localizes at the mating projection tip.