PharMolix/UniProtQA huggingface dataset:
Protein: SYGA_FRATN
Sequence: MLTFQEIILKLHHYWASKGCAIIQPLDMEVGAGTFHPATTLRAIGPEPWTAAYVQPSRRPTDGRYGENPNRTQHYYQYQVVMKPSPDDIQELYLGSLRELGIDPLENDIRFVEDNWESPTLGAWGLGWEVWSNGMEITQFTYFQQVGGLECKPVMGEITYGLERLAMYIQNVDSMYDILWANTQNGPLYYRDVFLQNEVEMSTYNFEEANVEELFKQFDLLEKEGYRLIEKNLPIPAYEFVLKASHTFNLLDARHAISVTERQGYILRVRKLALEVAKEYYSAREKLGFPAFKKDN
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_DESHD
Sequence: MEQLTPRETVRELDRYIVGQNQAKRAVAIALRNRYRRSLLPEGMQEEVLPKNILMIGPTGVGKTEIARRLAKLVRAPFLKVEATKFTEVGYVGRDVESIVRDLVEISLRMVKAEKMEEVEIQAAQAAEKRLEALLVPGKRQENNSSNPFQFLFNQGQEKEETVTPEIERDRTFIRERLHRGELDEQVIEVEVEDNQPLLPDFLGTGMEINTNLQDMMAGMLPKKRHKRKVTVREARRILTTEEAQKLIDHDEAVQEAIRRVEQEGMVFLDEIDKIAGRDGASGPDVSRGGVQRDILPIVEGSTINTKYGPVKTDHILFIAAGAFHVAKPSDLIPELQGRFPIRVELESLSIEDFQRILTEPQSSLIKQYSALLETEGIKVEFTENAIDELAKVAYEVNSNTENIGARRLHTIVERVLEELSFEASELPEDYTVTINREYIQHRLGNIVRNQDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIL2_SCHPO
Sequence: MGKNTDKLYITQTEHSGVHGWHGGMSGIAQKNSTTSYKQLPFNYCSLSLQPFNHPCCLVDETKQAIIFDFRFIVPWLRKHGTNPINGQKASMSDLIKLKFAKNSAEEYCDPVTMKSFTRFSHIVAIRSTGNCFSWDTIERLNIKPKHWRDLVNEEQFTRDDIITIQDPHNVENRDFSAIQKQKETARDEKITKAKIALQASRAKSTESTSSPELSHSLDSSKSIASDMPIHRASHTTGYAAASLTSTSFTPVTKNERAIIAEEDYMLNHTRIKHKGYARIVTNHGEINIELHTDYAPHAVYNFVQLAKQGYYRNTIFHRNIARFMIQGGDPSGTGRGGQSIWGKPFKDEFCNPLKHDDRGIISMANRGKNTNGSQFFILYGPAKHLDNKHTIFGRVVGGLNVLDALEKVPTNSNDHPKLPIKLEDIIIFVDPFEEWKKDEREKEKRKRQEEEEENNLDRTSWTGRDLSASSTDHSLNASVGKYLKKEVSLEEKTFTSTVNPKKKKARTGFGNFDAW
What is the function of this protein?
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins.  May also function as a chaperone, playing a role in intracellular transport of proteins.  May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on proteins.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase cyp8, PPIase cyp8, RING-type E3 ubiquitin transferase cyp8, Rotamase cyp8.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSH_ALISL
Sequence: MEKDLKFTASHEWVRENGDGTVTVGISNHAQGLLGDVVFVDLPDVDDEVTAGENFSLVESVKAASDIYAPISGVIVEINEELEDSPELVNEEPYEGGWIARIKLSDDGDLENLIPGDQYLESIEEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: XPT_STRP6
Sequence: MQLLEERILTDGNILGENILKVDNFLTHQVDYRLMKAIGKVFAQKYAEAGITKVVTIEASGIAPAVYAAEAMDVPMIFAKKHKNITMTEGILTAEVYSFTKQVTSTVSIAGKFLSKEDKVLIIDDFLANGQAAKGLIEIIGQAGAQVVGVGIVIEKSFQDGRRLIEDMGIEVTSLARIKNFENGNLNFLEADA
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_DELAS
Sequence: MIGDWNNGTGRRKSSVARVFLKKGSGKITVNGKDIQEYFGRETSIMIAKQPLALTSNLEAFDIQVNVHGGGESGQAGATRHGITRALIDYDAALKPVLSQAGFVTRDAREVERKKVGLRSARRAKQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: SINA_SCHMA
Sequence: MNNSITEVNMSVPSRATNSNNTILSEERTCHRSQMASSDAVGRTMALLPINHNHALHHGIKLMPHINMPHREVGATTPLVTNSGTASTCSMSLPGSMSSASDTVCNILPHNTSDSSSIDLASLFECPVCMDYALPPIMQCQSGHIVCASCRSKLSSCPTCRGNLDNIRNLAMEKLASSVLFPCKYSTSGCPETFHYTSKSEHEAACEYRPYDCPCPGASCKWLGELEQVMPHLVHHHKSITTLQGEDIVFLATDISLPGAVDWVMMQSCFGHSFMLVLEKQERVPDQIFFALVQLIGTRKQADQFVYRLELNGHRRRLTWEACPRSIHDGVQSAIAVSDCLVFDSNTAHSFAENGNLGINVTISQVSPSIS
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins.  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.  Mediates the ubiquitin-mediated degradation of nuclear receptors for retinoids SmRXR1 and SmRXR2.
What are the official names of this protein?
E3 ubiquitin-protein ligase sina, RING-type E3 ubiquitin transferase sina, Seven in absentia homolog, SmSINA.
What is the protein family that this protein belongs to?
Belongs to the SINA (Seven in absentia) family.
Protein: MNMG_ROSCS
Sequence: MDSIHPFIYDLIVVGAGHAGCEAAHAAARMGCRTLLLTIDLDKLAHMSCNPSIGGPAKGHLVREIDALGGLMGRVTDRTFIQIRLLNESKGPAVQAPRAQADKRLYAKVMKETLETTPNLDLRQAMIERILLPQPPGRNGSAAPADDPAGVQPGHYAVITHTRRVYQSRALVLTTGTFLRGRAITGEAIWGAGRAGEAPATALGEDLAALGFPLVRLKTGTPPRIDARTIDFSQTSVQQGSPTPLFFGHYYRVLGEIPPEPAFTGAPACAYPEPLRAAWRPQLPCYLVHTTPEFHEIVRRNLDRAPLFSGIIEGVGPRYCPSIEDKIVRFADKERHGLFLEPEGWSTHEVYVQGCNTSLPEDVQWAMLRSIPALRRVELMRAGYAIEYDALATGEIAADMSSRRIPGLFFAGQINGTTGYEEAAAQGLMAGINAARFIQGKPPIILRRDEAYIGVLIDDLITKEIREPYRMFTSRAEHRLLLRTDNADLRLTRLAGELGLVDRERVEAVERKREESERLLRVLRGQRLFPSAATNARLSDVGIAPLSSEMSAEDVLRRPEVRYEQLRQALDLPACDADIAEQVEIEAKYGGYLQKQQREVERLRRMEARRIPPDFDFTALRGLRNEARQTLQRFRPATVGQAARLAGINPADVAILIVALERRGRRDMALDVRSGA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_BRUA2
Sequence: MKRTYQPSKIVRKRRHGFRARMATTGGRKVLAARRTRGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL333_STAAB
Sequence: MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PAX9_MOUSE
Sequence: MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQGHYDSYKQHQPAPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAIPGSVALPRTWPSSHSVTDILGIRSITDQGVSDSSPYHSPKVEEWSSLGRNNFPAAAPHAVNGLEKGALEQEAKYGQAPNGLPAVSSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGHGWQHAGSTPLSPHNCDIPASLAFKGMQAAREGSHSVTASAL
What is the function of this protein?
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
What are the official names of this protein?
Paired box protein Pax-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: MATK_PHYCU
Sequence: MAEFKRYLELDISQQHDFIYPLLFQEYIYALAHDHGLNRSIFLENAGYDNKSSLLIGKRLITHLITQMDQQKKFLVPDSDSNQKKNLGYNTNLYSQMIFEGFAVVMEIPFYLRLLSFLEGKERVKSHNXXXXXXXXXXXXXXXXXXXXXXDIQIPHPIHLEILVQTLRYWVKDASSLHLLRFFLHEYPIWNSLITQKKSIFSFSKKNQRFFLFLYNFHVCEYESIFVFLRQPTSHLRSISSETFLERISFYRKIELEVFTKDFKSILWLFKEPFLHYVRYRGKAILASKGTSLLMNKWKYYLLNFWQSYFYMWSQPRRIHINQLSNHFLDFLGYLSSVRLKPLMLRSQMIENSFLIENASKKFDTLMPITPMILSLYKAKFCNVLGHPMSKPAWSGLSDSDIIERFGRIYRNLSHYYSGSLKKMSLYRIKYILRLSCARTLARKRKSTVRAFLKRLGVGLLAEFFTEEEQVFYLTFQKVSFTSGELYRRRIWYLDIICINDLANYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBL20_ARATH
Sequence: MNGGPSGFHNAPVTKAFVITSALFTVFFGIQGRSSKLGLSYQDIFEKFRIWKLIMSTFAFSSTPELMFGLYLLYYFRVFERQIGSNKYSVFILFSGTVSLLLEVILLSLLKDTTANLLTSGPYGLIFASFIPFYLDIPVSTRFRVFGVNFSDKSFIYLAGVQLLLSSWKRSIFPGICGIIAGSLYRLNILGIRKAKFPEFVASFFSRLSFPSFGNSPPPAPSRNIVGTISPNTGRRAERSQPAPLPSSVEPSEEAITTLVSMGFDRNAARQALVHARNDVNAATNILLEAQSH
What is the function of this protein?
Probable rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid-like protein 20, AtRBL20.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UGT1_PUEML
Sequence: MKDSIVLYSALGRGHLVSMVELGKLILSHHPSLSITILFLTPPPNQDTPTSPTAFTCDATAKYIAAVTAATPSITFHRIPQISIPTVLPPMALTFELCRATGHHLRRILTSISQTSNLKAIVLDFMNYSAARVTNTLQIPTYFYYTSGASTLAVLFQQIIIHQNNTKSIKDLNMHLLIPGLPKIHTDDMPEQVQDRENEGYEVFIDIATCMRDSDGVIVNTFEAMEGRVMEAFNEGLMEGPTPPLFCIGPVISSAPCRVDDDGCLSWLDSQPSHSVVFLSFGSMGRFSRTQLREIAIGLEKSEQRFLWVVRSEFEEGDSVEPPSLDELLPEGFLERTKGKGMVLRDWAPQAAILSHDSVGGFVTHCGWNSVLEAVCEGVPMVAWPLYAEQKLNKVILVEEMKVGLAVKQNKDGLVSSTELGDRVRELMDSDRGKEIRQKIFKMKMSANEAMAKGGSSIMALNRLVEVWREH
What is the function of this protein?
Isoflavone 7-O-glucosyltransferase converting daidzein to daidzin, genistein to genistin and formononetin to ononin (PubMed:24700248).  Shows some activity toward the chalcone isoliquiritigenin, the flavanones liquiritigenin and naringenin, and the flavone apigenin, but not toward cyanidin, luteolin, kaempferol, quercetin, daidzin and puerarin (PubMed:24700248).
What are the official names of this protein?
UDP-glycosyltransferase 1, PlUGT1, Glycosyltransferase UGT88E12, UDP-glucose:isoflavone 7-O-glucosyltransferase KGT1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: ACNA_SALTY
Sequence: MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDIARLPKSLKVLLENLLRWQDGESVTDEDIQALAGWLKNAHADREIAWRPARVLMQDFTGVPAVVDLAAMREAVKRLGGDTSKVNPLSPVDLVIDHSVTVDHFGDDDAFEENVRLEMERNHERYMFLKWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDSLVGTDSHTTMINGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLRKHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAITLEYMRLSGRSDDLVELVETYAKAQGMWRNPGDEPVFTSTLELDMGDVEASLAGPKRPQDRVALGDVPKAFAASAELELNTAQRDRQPVDYTMNGQPYQLPDGAVVIAAITSCTNTSNPSVLMAAGLLAKKAVTLGLKRQPWVKASLAPGSKVVSDYLAQAKLTPYLDELGFNLVGYGCTTCIGNSGPLPEPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNINLATDPLGYDRKGDPVYLKDIWPSAQEIARAVELVSSDMFRKEYAEVFEGTEEWKSIQVESSDTYGWQSDSTYIRLSPFFDEMQAQPAPVKDIHGARILAMLGDSVTTDHISPAGSIKPDSPAGRYLQNHGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMLPGVEGGMTRHLPGTEAMSIYDAAMLYQQEKTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESFERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEVIDIADLQNLRPGATIPVTLTRSDGSKETVPCRCRIDTATELTYYQNDGILHYVIRNMLN
What is the function of this protein?
Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route).  Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate.  Also catalyzes the hydration of 2-methyl-cis-aconitate to yield (2R,3S)-2-methylisocitrate.  The (2S,3S)-2-methylcitrate (2-MC) is a very poor substrate (PubMed:11294638).  The apo form of AcnA functions as a RNA-binding regulatory protein (By similarity).
What are the official names of this protein?
Aconitate hydratase A, ACN, Aconitase, (2R,3S)-2-methylisocitrate dehydratase, (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase, 2-methyl-cis-aconitate hydratase, Iron-responsive protein-like, IRP-like, RNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family.
Protein: PYRD_RHIE6
Sequence: MIDPFKRLARKGLFLFDPETAHGMSIAALKSGLVPACQITPDPRLRQTVAGLTFENPLGMAAGYDKNAEVPEALLRLGFGFTEIGTVTPRPQSGNPRPRIFRLVEDEAVINRLGFNNEGHEAAFERLSALTGKGVVGVNIGANKDSEDRITDYVAGIRCFYSVARYFTANISSPNTPGLRDLQARESLAALLSAVLAARDEMAERSGRKIPVFLKIAPDLTEEGMDDIAAEALAHPLDGLIVSNTTLSREGLKDQRQAKETGGLSGVPLFEKSTAVLARMRKRVGAALPIIGVGGVSSAETALEKIRAGADLVQLYSCMVYEGPGLPGNIVRGLSGLLDREKAGSIRELRDSRLDYWAARKV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PB1F2_I18A0
Sequence: MGQEQDTPWILSTGHISTQKREDGQQTPRLEHHNSTRLMDHCQKTMNQVVMPKQIVYWKQWLSLRSPTPVSLKTRVLKRWRLFSKHEWTS
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: RR2_SOLTU
Sequence: MTRRYWNINLEEMMEAGVHFGHGTRKWNPKMAPYISAKRKGIHITNLTRTARFLSEACDLVFDAASRGKQFLIVGTKNKAADSVEWAAIRARCHYVNKKWLGGMLTNWSTTETRLHKFRDLRMEQKTGRLNRLPKRDAAMLKRQLSRLQTYLGGIKYMTGVPDIVIIVDQHEEYTALRECITLGIPTICLTDTNCDPDLADISIPANDDAISSIRLILNKLVFAICEGRSSYIRNP
What are the official names of this protein?
30S ribosomal protein S2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURD_BACVZ
Sequence: MENELFLQKQNFLVLGLAKSGYAAASILHEKGINVVVNDQKAFEENEPAQRLAERGIEVICGEHPTSLFDQHHITILIKNPGIPYENIMVEEAQRRGIPVWTEIELAYYITNAKFIGITGSNGKTTTTTLIYEMLKADSIKTLIAGNIGTVASEVAYHADGDEWIVTELSSFQLMGTHAFRPEIGLILNVFDAHLDYHHSRENYEKAKQNVYLHQLESDTAIVNQSDETVVRLAESGKAGTVPFSVHQELSSGAFIKDGMLMFGDEAILPVDDIVLPGAHNLENILAAVAAAKTAGASNKAIQKVLTSFTGVKHRLQYVTAIQNRKFYNDSKATNILATSKALSAFKAPVILLAGGLDRGNGFDDLKPYMDNVKAVLTFGQTAPKIEKLGNELGIQHVKRVDNVEQAVSAAFALSNEGDVILLSPACASWDQFKTFEERGDMFIDAVHMLK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUTA_ECO5E
Sequence: MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKSDFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPVLTQEVA
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: CH603_RHOBA
Sequence: MPKIIAFDQEAREAIRRGVSKLARTVKVTLGPKGRNVILQKSFGSPTVTKDGVTVAKEIELEDPYENMGASMVREVASKTSDVAGDGTTTATVMAEAIFNEGLKAVVAGVNPIQMKSGIETAVSDITEQLHSMAVKVKDQEAMANVATIASNNDREIGTLLADAMSKVGKDGVITVDEGKSLQTEQEWVEGMQFDRGYLSPYFVTDSTSMEVVLEDAYVLVFEKKISNIKDMVPLLEKVVQQGKPLLIIAEDVDGEALATLVINRLRGTFTVCAVKAPGYGDRRKAMMEDIAILTGGQAIFEALGVKLESVDLPQLGRAKKIIVDKDNTTVIEGGGKSADIKARIDQIRREIELSTSDYDREKLEERLAKLAGGVAKVNVGAATESEMKEKKARVEDALHATRAAVEEGILPGGGVALLRASGKVKAADTLTDDQLVGYNIVLRACRAPLTMISENAGQDGGIVCEKVLAMKGNEGYNALTDVYEDLVKSGVIDPTKVTRTALGNAASVATLLLTSDALVAEKPEKSGKAGHGGDHDMY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 3, 60 kDa chaperonin 3, Chaperonin-60 3, Cpn60 3.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SODC_PINSY
Sequence: MGLLKAVVVLNGAADVKGVVQFTQEGDGPTTVTGKISGLSPGLHGFHVHALGDTTNGCMSTGPHFNPLGKEHGAPTDDNRHAGDLGNVTVGTDGTVEFSITDSQIPLSGPHSIVGRAVVVHADPDDLGKGGHELSKSTGNAGGRLACGVVGLQG
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Cu-Zn].
What is the protein family that this protein belongs to?
Belongs to the Cu-Zn superoxide dismutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP_CYTH3
Sequence: MSKVLPKRSDDYSLWYNELVKRADLAENAPVRGCMIIKPYGYSIWEKMQAVLDKMFKETGHSNAYFPLFIPKSYLSKEASHIDGFAKECAVVTHYRLKNDENGKGIIVDPEAKLDEELIVRPTSETVIWNTYKTWIQSHRDLPLLINQWANVVRWEMRTRLFLRTTEFLWQEGHTAHATKQEAIVETEQMMNVYATFAQNFMALPVHRGIKSANERFAGAEETYCIEALMQDGKALQAGTSHFLGQNFAKAFDVKFASKEGSLEYVWGTSWGVSTRLMGALIMAHSDDEGLVLPPLLAPIQVVIVPIFKTAEQLDLIEATLKPILAALKAKDISVKFDHSDKYSPGFKFAEYELKGVPLRVAIGARDIENGTVELARRDTKEKTTVPQEGLADTIEKLLQEIQENIYKKAFAYREANTFVADDYTTFKTMLDETPGFILAHWDGTPETEEKIKEETKATIRCIPLDVTSEPGICMVTGKPSAQRVLFARAY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_MYCBP
Sequence: MAVVPIRIVGDPVLHTATTPVTVAADGSLPADLAQLIATMYDTMDAANGVGLAANQIGCSLRLFVYDCAADRAMTARRRGVVINPVLETSEIPETMPDPDTDDEGCLSVPGESFPTGRAKWARVTGLDADGSPVSIEGTGLFARMLQHETGHLDGFLYLDRLIGRYARNAKRAVKSHGWGVPGLSWLPGEDPDPFGH
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: EX7S_BEUC1
Sequence: MSQEPPARPDPATLSYEQARAELVDVVQRLEQGAATLEDSLALWERGEALAARCQEWLDGARDRLARVSPASGGATEAPAPAERDR
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_CALBD
Sequence: MIVIPAIDLIDGKCVRLTQGDYSQVQLFNSDPIEQAKLFEKSGAKYVHVVDLDGAKVGRPVNFEVIRNIKRVTSLTVECGGGIRDKATVELYISSGVNYIILGSVIFKNPDFVNEVMKVFGKERFIASLDFKDGFVKLSGWQEATTITIEEGIMKIKTLGFERLIYTDITTDGMLKGHNFEAAKYIRELFDGFLTASGGISTKEDIMRLKSIGVDAAVVGKALYTGQLKLEEVINLL
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_STRLA
Sequence: MPPKKKKVTGLIKLQIKAGAANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGMVVPVEITVYEDRTFTFITKTPPAARLILKAAGIEKGSGEPHKTKVAKLTGAQVREIAELKMPDLNANDVDAAMKIIAGTARSMGVTVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RSMJ_PSEA8
Sequence: MTDSAAPRLHVQALSAGCAEAARRWAERLGLPLAADDEAEFAVQVGEQGLQVLQLGADSPGPVRVDFVEGASAHRRKFGGGSGQMIAKAVGVQPGIRPRVLDATAGLGRDGFVLASLGCEVTLVERQPLIAALLEDGLERARRDPDVAPIAARMRLLGGNSADLMRAWDGEAPQVVYLDPMFPHRDKSALVKKEMRLFRPLVGDDLDAPALLQAALALASHRVVVKRPRKAPIIEGPKPGYSLEGKSSRYDIYPKKALGKG
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.