PharMolix/UniProtQA huggingface dataset:
Protein: SHAN2_MOUSE
Sequence: MKSLLNAFTKKEVPFREAPAYSNRRRRPPNTLAAPRVLLRSNSDNNLNAGAPEWAVCSAATSHRSLSPQLLQQTPSKPDGATKSLGSYTPGPRSRSPSLNRLGGTAEDGKRTQPHWHVGSPFTPGANKDSLSTFEYPGPRRKLYSAVPGRLFVAVKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGHIGWFPAECVEEVQCKPRDSQAETRADRSKKLFRHYTVGSYDSFDAASDCIIEDKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLILKVVTVTRNLDPDDTARKKAPPPPKRAPTTALTLRSKSMTAELEELGLSLVDKASVRKKKDKPEEIVPASKPSRTAENVAIESRVATIKQRPTSRCFPAASDVNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPPPSPTTYNCPRSPTPRVYGTIKPAFNQNPVVAKVPPATRSDTVATMMREKGMFYRRELDRFSLDSEDVYSRSPAPQAAFRTKRGQMPENPYSEVGKIASKAVYVPAKPARRKGVLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSMEIDPQATEPGQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLSTDLGDEDVGLGPPAPRMQASKFPEEGGFGDEDETEQPLLPTPGAAPRELENHFLGGGEAGAQGEAGGPLSSTSKAKGPESGPAAPLKSSSPAGPENYVHPLTGRLLDPSSPLALALSARDRAMQESQQGHKGEAPKADLNKPLYIDTKMRPSVESGFPPVTRQNTRGPLRRQETENKYETDLGKDRRADDKKNMLINIVDTAQQKSAGLLMVHTVDVPMAGPPLEEEEDREDGDTKPDHSPSTVPEGVPKTEGALQISAAPEPAVAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFLFTEPLPPPLEFANSFDIPDDRAASVPALADLVKQKKNDTSQPPTLNSSQPANSTDSKKPAGISNCLPSSFLPPPESFDAVTDSGIEEVDSRSSSDHHLETTSTISTVSSISTLSSEGGESMDTCTVYADGQAFVVDKPPVPPKPKMKPIVHKSNALYQDTLPEEDTDGFVIPPPAPPPPPGSAQAGVAKVIQPRTSKLWGDVPEVKSPILSGPKANVISELNSILQQMNRGKSVKPGEGLELPVGAKSANLAPRSPEVMSTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRTSGPRRAPSPVVSPTELSKEILPTPPPPSATAASPSPTLSDVFSLPSQSPAGDLFGLNPAGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLGEHKETFMDNEIDGSHLPNLQKEDLIDLGVTRVGHRMNIERALKQLLDR
What is the function of this protein?
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton.  May play a role in the structural and functional organization of the dendritic spine and synaptic junction (By similarity).
What are the official names of this protein?
SH3 and multiple ankyrin repeat domains protein 2, Shank2, Cortactin-binding protein 1, CortBP1.
What is the protein family that this protein belongs to?
Belongs to the SHANK family.
What are the subcellular locations of this protein?
Apical cell membrane. Cytoplasm. Synapse. Postsynaptic density. Cell projection, dendritic spine. Cell projection, growth cone. Note=Colocalizes with cortactin in growth cones in differentiating hippocampal neurons. Colocalized with PDE4D to the apical membrane of colonic crypt cells (By similarity). Present in the dendritic spines of cerebellar Purkinje cells.
Protein: E1B55_ADE40
Sequence: MERPNSSVAGLYSGLHGNGSVENLATEEEGLRLLAGAASARFGSSAGRGGGGGEPEGRPGPFNGIVTEPDPEEGTSSGQRGGINGQRGTKRKMENEGEDFLKELTLSLMSRRHHESVWWADLEDEFKNGEMNLLYKYTFEQLKTHWLEAWEDFELALNTFAKVALRPDTIYTIKKTVNIRKCAYVLGNGAVVRFQTCDRVAFNCAMQSLGPGLIGMSGVTFMNVRFVVEGFNGTVFASTTQLTLHGVFFQNCSGICVDSWGRVSARGCTFVACWKGVVGRNKSQMSVKKCVFERCIMAMVVEGQARIRHNAGSDNVCFLLLKGTASVKHNMICGGGHSQLLTCADGNCQALRVFHVVSHPRRPWPVFEHNMLMRCTVHLGARRGMFSPYQSNFCHTKVLMETDAFSRVWWNGVFDLTMELFKVVRYDESKVRCRPCECGANHIRLYPATLNVTEQLRTDHQMMSCLRTDYESSDED
What is the function of this protein?
Plays a major role to prevent cellular inhibition of viral genome replication.  Assembles an SCF-like E3 ubiquitin ligase complex based on the cellular proteins ELOB, ELOC, CUL5 and RBX1, in cooperation with viral E4orf6.  This viral RING-type ligase ubiquitinates cellular substrates and targets them to proteasomal degradation: TP53/p53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM.  Degradation of host TP53/p53 activity is essential for preventing E1A-induced TP53 accumulation that would otherwise lead to cell apoptosis and growth arrest.  E1B-55K also inactivates TP53 transcription-factor activity by binding its transactivation domain.  E1B-55K also functions as a SUMO1 E3 ligase for TP53 which causes the latter to be sequestered in promyelocytic leukemia (PML) nuclear bodies thereby contributing to maximal inhibition of TP53 function.
What are the official names of this protein?
E1B 55 kDa protein, E1B-55K, E1B protein, large T-antigen, E1B-495R.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E1B 55 kDa protein family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=Colocalizes with host TP53 to host PML nuclear bodies. PML localization of E1B-55K is necessary for E1B-55K-dependent SUMOylation of TP53.
Protein: HGD_PSE14
Sequence: MAIHSRSDALAYQSGFGNQFSSEALPGALPIGQNSPQKHPLGLYAEQFSGTAFTVARSEARRTWLYRIKPSAAHPRYQRMGRQIAGQEQGPINPNRLRWNAFDIPAEPVDFIDGLIPLASTSAADQADGVSVYVYAANTSMQRAFFSADGEWLIVPQQGRLRIITELGLLDIEPLEIAVLPRGMKFRVQLLDSSARGYICENHGCALRLPELGPIGSNGLANPRDFLTPVAWFEDNQQPVELVQKFLGELWSTHLEHSPFDVVGWHGNNVAYKYDLRRFNTIGTVSYDHPDPSIFTVLTSPGAAHGQANIDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLIDGAYDAKAEGFMPGGASLHNCMSAHGPDNVTAEKAIAAELKPHKIENTMAFMFETGKVLRPSRHALGCPQLQADYDACWNDMTRTFNKEPRR
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: MURD_LACJO
Sequence: MKKIKTYENKNILILGLGKSGFSVAKLLLKLGAKLTLNDKKDLSNDDRAAELGKLGVRVISGYHPVEIFDEEKFDYLVKNPGIPYENPMVEKAEKLDIPVITEPEIALNVSEAPYVCVTGSNGKTTTVMLTQRIMDHNLSKNGGHAYAVGNIGVPISEVVEKATSKDLLVVEMSSFQLLGVTDIKPKVAAIVDIYNNVHLDYHKTFDNYVEAKLRITQSQDQDDYFIANFDQKNILEKELDKTKAKVQTFSETDKTADYFIGDEYLESKDDHHIMKISDIKIPGIHNQQNCLVAIAISKLMGADDSDIQYALSTFTGATHRLQYVMTYNDRKIYNDSKSTNIEAATVAIPSFKEPEVLIAGGLDRGFMFDSLVPLFKKHVKSIVLYGETKYLLADAARKAGIKDIVIVNTLQEAVPRAYELSEAGDVILFSPACASWDQFNTFEERGDFFVKFIKELKTK
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_CROS8
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: PSBD_CUCSA
Sequence: MTIAVGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YQGF_GEOTN
Sequence: MRTLGLDLGTKTLGVAVSDEFGWTAQGLETIAIDEERGHYGFERLRAIIDEYGVDTIVVGWPKNMNGTLGPRAEASERFAAKLREEFSLPVVLWDERLSTMAAERMLIAADVSRKKRRKVIDKMAAAVILQSYLDSKR
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CARRP
Sequence: MINYLKFNRFCFSKKKFFHKCNLPYLLHNQIGSYNSFLSSKYNSLFSIKKVLKQYFPLICNNKNIFIKLKKIELLEPCNTEKYTKIRNLHLFSTLYMYISIYVINKNLNVYKKIFLGNIPSMTKKGNFIINGIDRILISQFTKSYGIYFYTEKKKKKCIIIPLKGSWLEFIITNNFLIVFDKKINFEINVFLICLGYNKKYFFNFFFFKIKIKIIRGKKRIFFLLNKKKYFYKIYNKYICISIKKILGKLFGKNYFLKKNTFLKFNIIDINKVNLILNYPIYFFFIIFLKKIINLNYLIYIYKNFKLKINKELLQYKKGYIINFFRNLFYKKKYFYSLIGAKRIFKRLFLKKNNKLTIYLEIIKKILKFIKFNIQNDNFDNLENKLILNCGKLLSIKFDFLFKKVIKFINYKMNNFKKYKDLDFIVNSDIITIGLKDYFCNNELSQFLDQNNPLAEISHNRKISLISGIGIEKENCGFDIRDIHYSHYCKVCPIDTPEGHNIGLINSLAYLSKVNKYNFISTIYKISILGKILGITFLDNKFDKHKFIVNFNSTIETIYGEIFRSPYFEARKTNYYYYKKFLNIDLIEICGDQIISVGASLIPFLSHNDANRCLMGSNMQRQAVPLIDSENPIVGTGNELEIGLNSNYNILSDLNGYVLYSDNYKIIIKNNNFIKTYFLEKYTRTNQNTILNQYTKVLKGDFVKVGNIIADSNSTKNGEISLGKNLRVAFMSWYGYNFEDSILLSSSILNKNNFNSIHIYEFITVLKYNENGFEIVSNECFGSNEKIKNKVKNGIIKIGEFVFSKDVIVGKMIPKKKRKFSPEEKLFKIVFSESNFNYYEQPLTVPKNIKGTIIAVNDFKIFYFKNKIFKLLKFEQLNYTCKNINNFFYETFNYYLTKIKKLLFNNKITIKKKRINSYNININNIFKIKCFNKKINFKLNIFKNIISNELLKKKNIFVYKKINFIKHDDFENSIIRIIKIKIAVKKQIAIGDKMSGRHGNKGVVSNIIDYENMPYDKFGNKIDLILNPLGVPSRMNVGQLLEVFLAGSLNLIKSFFLKIKNLNKISYFKMKLFIKIIFKCIYDKNINLNIFNNSLVLKIFKNIKNQLNVCVHNFYNFNVNKVNNIIKTIGINKNCELLLFDGITGKRYLQLVNVGYIYFMKLNHLVIDKIYSRSIGPYSIVTQQPLGGKSNLGGQRLGEMEVWALEAYGAAFLLKEMLTIKSDDILGRIELYKNIIKGINDANSGIPESFQVLMKEIQSLCFDIKIL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: SSPO_GEOTN
Sequence: MAKRKANHVIPGMNAAKAQGMGAGYNEKFSNEPLTEAQRQNNKKRKKNQ
What are the official names of this protein?
Small, acid-soluble spore protein O, SASP O.
What is the protein family that this protein belongs to?
Belongs to the SspO family.
What are the subcellular locations of this protein?
Spore core.
Protein: PYRE_THEP3
Sequence: MEKEEVLEIFSKLGVINKGHFLLTSGKHSDTYLQCAKIFQYPKYSEIFSKELALKFKGHEIDVVIGPAIGGIILAYEVARQVGAKALFAEREEGVMKLRRGFEIKEGENVLVVEDVVTTGGSVKEVINLVNSLKGNVIGVGSIVDRSDGKVNFEVPFKSVVSLYVETYEKEECPLCKEGIPLVKPGSRKF
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: HIRA_ORYSJ
Sequence: MITEKPSWIRHEGLQIFSIDIQPGGIRFATGGGDQKIRIWSMKSVAKDNDSDDSSQRLLATIRDHFGTVNCVRWAHHGRYLASGSDDQVIQIHERKAGTGTSEFGSGEPPDVENWKVVMTLRGHTADVVDLNWSPDDSTLASGSLDNTVHIWSMANGICTAVLRGHSSLVKGVTWDPIGSFIASQSDDKTVIIWRTSDWSLAHRTEGHWSKSLGSTFFRRLAWSPCGHFITTTHGFQKPRHSAPVLERGEWSATFDFLGHNAPVVVVKFNHSMFRKHLSSGQDAKAAPAGWANGASKASSKEHQPYNVIAIGSQDRTITVWTTASARPLFVAKHFFTQSVVDLSWSPDGYSLFACSLDGSVATFHFEAKELGYRLRDAELDELKKNRYGDVRGRQSNIAESPAQLLLEEASAKQSASKKVSSVQQFQSPPKVSTDAPNPSTSVPNQKAPEALPEDEKKTAGSTADDINKAPRLSSPVKQREYRRPDGRKRIIPEAVGFPSNQDMSNRSQNQGVDFSSLDQRMILGENGTRPSYSASGNCNNCGVRERSGITARTNISESLVIQKASAGAGSDGRLSIEQSGSVVPGSLASCSSLSIHVFNKKDNEDSLPVRLEAKPVERSAGDMIGLGGAFSTKETEITCTRGTETLWSDRISAKVTVLAGNANFWAVGCEDGCLQVYTKCGRRAMPAMMMGSAAVFIDCDECWKLLLVTRRGLMYIWDLYTRTCVLHDSLASLVTSPDEAAGKDTGTVKVISAKFSRCGSPLVVLASRHAFLYDTSLKCWLRIADDCFPASNFASSFSSTQGGELGKLQIDIGKFMARKPIWSRVTDDGVQTRSHLETQLAASLALKSPQEYRQCLLSYIRFLAREADESRLREVCESFLGPPMGMVDAASSADLKNPSWDPDVLGMKKHKLLREDILPSMATNRKVQRLLNEFMDLLSEYEAAETNVEQMDVTPTPPPPPPAAATEGNNNGAS
What is the function of this protein?
Histone chaperone involved in maintining knox genes silencing throughout leaf development.
What are the official names of this protein?
Protein HIRA, Histone regulator protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2130_HALHL
Sequence: MSGLRLIVVSGLSGSGKSVALHTLEDAGYYCIDNLPVSLIGELARYAQNRDAPTGERFAVGLDARNPPHDLQCLPETLTALREQGIATEVLFLYAEDSILMRRYSETRRRHPLAEGDQPLADALRAERTLLEPLREVADWSIDTSRTTVHDLRGLISERVAGERSGLSVLVQSFGFKHGIPTDADYVFDARCLPNPHWEPQLRAYTGCDDCVRAFLESQPETEILFGQIDTLIRYWLPVHQQAGRSYLTVAVGCTGGQHRSVYLAERLAESLQEGCSHVSLRHRELS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Hhal_2130.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: FOLD2_SINMW
Sequence: MGMDRIADRAIIDGKRFAAGLLDDITARVKKLEEETGQVPGLAVVLVGEDPASRVYVGSKHRQTLAAGIASFKYELPAETTQEELMALIDRLNVDPAVHGILVQLPLPAHLDANAVIQEINPNKDVDGFHISNAGRLATGQPAFVPCTPLGCLLLLKDRLGANLSGLHAVVLGKSNIVGRPMVQLLLAESCTVTIAHSRTRNAPELCREADILIVAVGRPGLVRGDWIKPGAVVIDVGINRVEAEGKSRIVGDVAFEEAGHAGAITPVPGGVGPMTIACLLSNTLTAFCRQHAVNID
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PFA4_CRYNB
Sequence: MAARNWSRVWVGGTVILISFIAFSSQIFVIWPWYGREISLDLLKLLVPLNLAAFMIFWNYRLCVITSPGSVPEGWRPNIGAMDGMEVKKGTHTPRYCKNCEHYKPPRAHHCRQCKTCWLKLDHHCPWIGNCVGFYNQGHFIRFLLWVDIGTTFHLIIMVRRVLYIAEYYHQEPTLADVLFLVFNFATCVPVWLCVGMFSIYHVYLACGNSTTIEGWEKDKVATLIRRGKIKEVKYPYNIGIYKNIKSVLGPNPFLWLWPQKMQGDGLSFPVNPSAGDHTTQYFWPPQDPSRLPNPPPIPAHASPFVYGNNGFNPNLQPTNSLRARRSSTPHIDEDEHSHERDQYRHYSSGEERDNDSISTSSSPKPYLSDYDHYDEGPMYPGERMTALIPRVRRGSEGWEVAPGGGWNAYSGMMDEEVGWDDEVGYDEAPGEGPYVERPWEMRGRYNVYDTEEESGYAH
What is the function of this protein?
Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
What are the official names of this protein?
Palmitoyltransferase PFA4, Protein S-acyltransferase, PAT, Protein fatty acyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ISPG_BACAA
Sequence: MNEMTHRTKTRPVKVGNLTIGGNNELIIQSMTTTKTHDVEATVAEIKRLEEAGCQVVRVAVPDERAANAIADIKKQINIPLVADIHFDYRLALKAIEGGIDKVRINPGNIGRRHKVEAVVNAAKERGIPIRIGVNAGSLERHILEKYGYPTADGMVESALHHIKILEDLDFHDIIVSMKASDVNLAIEAYEKAARAFDYPLHLGITESGTLFAGTVKSAAGLGAILNKGIGNTLRISLSADPVEEVKVARELLKSFGLASNAATLISCPTCGRIEIDLISIANEVEEYISTLQVPIKVAVLGCAVNGPGEAREADIGIAGARGEGLLFRKGQVVRKVPEEIMVEELKKEIDVIAAEMAAEREKEKETQEQ
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TRPF_NEIMA
Sequence: MRKIRTKICGITTPEDALYAAHAGADALGLVFYPQSPRAVDIIKAQKITAALPPFVSVVALFVNESAQNIRRILAEVPIHIIQFHGDEDDAFCRQFHRPYIKAIRVQTASDIRNAADRFPDAQALLFDAYHPSEYGGTGHRFDWTLLAEYSGKPWVLAGGLTPENVDEAIRITGAEAVDVSGGVEASKGKKDPAKVAAFIATANRLSR
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: FLHD_NITEU
Sequence: MGTNQILDEIREVNLSYLLLAQQMLREDRIAAMYRLGIDEDIADILVKLTNSQLLKMAGSNMLLCRFRFDDSLIAEILTSHKQDRALTQSHAAILMAGLPAEKIS
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPD_HAEDU
Sequence: MSELSTVARPYAKAAFDFALEQGQLDKWQEMLQFSALVAENEQVVEYITSSLASGQISEIFLQICDDQLDQYGQNFIRVMAENKRLAILPEVFNRFNALRAEYEAIKKVIVVSATELSQAQEEKIAKAMEKRLGQKVRLTTEIDSTLLTGIIIKYDDIVIDGSSRGQLNRLTQALSL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MINC_THEVB
Sequence: MSEAESTPVEEPVVESTEGSEAIPEVEQSTPLVSGLTLEHCGGRYRLTLPSDLDWIDLWPQLQLYLVGQEHLWSETLPVDCACGQRLLDQSQLQQLAEALSEHQLRLDRIITGRRQTAIAAATLGYSVQQEELPPLLVKEADGPSQATANPLYLKTTLRSGIEIHHDASVIIVGDVNAGASIIAAGDIIVWGRLRGVAHAGAKGNLGARIMTLEMAATQLRIADLLARTPDPPRPPYPEVAYATDQGIQIAPAYTWGRVFAVSAAP
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: BIOF_TRIL1
Sequence: MPLQLLSQRLEKTQHDGLYRSLRSVERTTPQVFVEGRQALLFCSNNYLGLAEHPSLAQAAADAALQYGTSSAASRLVSGNQPLHAMLEAKLSAWKGTETALLFNSGYAANTGIIAALAGRGDIIFSDRLNHASIIDGALLSGARLIRYPHNDTLALARLLEQHQTDGLRLIVTDGVFSMDGDIAPLQGIADLAEQHRALLMVDDAHAGGVLGQQGRGTVDFCGVTGRVAIQMGTFGKALGSFGAYAACSRLVRDYLINRSRSLIFSTSLPPAVLAASAAAVELVQAEEGQQLRQQLTDNSHLLRYLLQQAGYKVPDGCTPIVPVMVGEAETTTRFSTRLLEEGVFVQGIRPPTVPKGTSRLRCTVMASHSPDQIQQAVAAITRVGRELGVL
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: YAV4_XANEU
Sequence: MEREMAHDERLHVHCGMGLGRTTIFIVMHDILRNAAMLSFDDIIERQRKFNPGRSLDNNKDVSDKGRSEFRNERSEFLPLFYEYAKQNPKGQPLLWSEWLDHNA
What are the official names of this protein?
Uncharacterized protein AvrBs1.1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: H4_PYCHE
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYCEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SYFA_LACP3
Sequence: MDLQTKLEQLFQQNNDTIKKVKSLDELNQIRVQLLGKKGPITGVLRGMKDLSAEERPKVGAFANKIRDDLSAVIEARKAQLEQAVINAKLASETVDVTLPGDPVEAGTPHIITQIMDDLEGFFMGMGYQVLTGPEVEEDHYNFEMMNIPKDHPARDMQETFYITNELLMRSQTSPMQARTMEKHDFTKGPLKMISPGVVYRRDDDDATHSHQFHQMEGLVIDKHITMADLKGTLLAMCQHVFGKDRTIRLRPSYFPFTEPSVEVDVSCFRCGGKGCPVCKYTGWIEVLGAGMVHPNVLRAANIDADVYGGFAFGLGPDRFAMLKYGIDDIRSFYTDDLRFLTQFSQEG
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_SALAR
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALMIERLRKIGFTIEHMDFGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARNERLDYCLVGEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDRGNDFFPATSMQVANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKERVHALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RISA_MYCTU
Sequence: MFTGIVEERGEVTGREALVDAARLTIRGPMVTADAGHGDSIAVNGVCLTVVDVLPDGQFTADVMAETLNRSNLGELRPGSRVNLERAAALGSRLGGHIVQGHVDATGEIVARCPSEHWEVVRIEMPASVARYVVEKGSITVDGISLTVSGLGAEQRDWFEVSLIPTTRELTTLGSAAVGTRVNLEVDVVAKYVERLMRSAG
What is the function of this protein?
Catalyzes the dismutation of two molecules of 6,7-dimethyl-8-ribityllumazine, resulting in the formation of riboflavin and 5-amino-6-(D-ribitylamino)uracil.
What are the official names of this protein?
Riboflavin synthase, RS.
Protein: BOMB_BOMOR
Sequence: MSAIPLNRILPLGFLFHLLIFSFISLSSCMEFVEDPNNQGRISLQQRLGNQWAVGHLMGKKSLQDTDFEEMESFAKRNVENMRAALLQEQNRAESERELRHAQLVVRNILEQYLKNMQN
What is the function of this protein?
Stimulates smooth muscle contraction.  Role in induction of hypothermia, stimulation of DNA replication and release of many gastrointestinal hormones.
What are the official names of this protein?
Bombesin.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted.