PharMolix/UniProtQA huggingface dataset:
Protein: RDR3_ORYSJ
Sequence: MYNPIGSAEAREPAELPAAVAAELERLEGRLRQLAGAEARRHLAVLGEAGAARVLRAVAESRRVRTLPGFIKYLAKREAAITRRDARGVPTALSAPAFISGPSREEESVYTQLFDNEVQMYDQSPSNEMATSLSNHGMVEVGSPNQQMPFHLHGNGGSVRQIARLVPQLAQLTVESPCGHTSSVSQNQGCIEVGTPTQAMVSPGLNQMALPCRCMPSGLQNYIEIDSPIQPMISTPRRVSTPSSVQDISRLIENMAGPSVSPPSPITAMPQNPTTTCHTTDNALREAASPQMLALEELGFRKIFMVFAYLASEKIENVLSVDYIRSLKFLSMAQFESQIWRTFGHKYIAASDRAKNLDSDPGMTKVYHCNVAIRGDTVVKIFKGPYIENTRTHLQKVVGDDNVLVVKFMGKLSDTKTDFSTYCEHYHKVAEDGIVLGLRRYRFFVYKDGGKEEKLKQEKIEDKNKCTSPVMCYFVRTESGWNMDEPYILSGRTVGQARELFMHISSAPTLAKYMARFALILSKTITWDADLSAVYVRRIKDEPCMDRHGNVVHKDQEPLIHTDGTGLVSVDLALNCPTSIFKGKFLKPQPLLMQFRLFYNGSAVKGTVLVDRRLPPATILIRPSMVKIETHPELSGVRSVNSSEIVSARNAKKSLSGVQSVNSFEIVSTSNRPRRTLTSRFLITLLCYGGVPEEYFLELLQSAIEGAENACYDYEDALRIAFSYADMEDSMSARMILSGIPLEESYLQHRLDFMAQQERKGIKQGKIPIDECYYLMDTTDPTGTLRPNEVCVILENGQFSGDVLVYKHPGLHFGDIHVLKATYIRDLEKEYVGYAKYAILFPISGPRSLADEMANSDFDGDIYWVSKNPKLLEHFKPSEPWVQAIKPKKTKQKKPQDCNESKLERLLFHEFLKTRFTPSFALGTAADSWLAYMDRLLTDSLDEIEKKLIEEKMLKLVDLYYLALDAPKTGNKVNIPSDLMVKQYPHFMGRSFSYHSSSILGQIYDKAEDVESLRSCNVQPIGVSLLPCFMEREAPPAARHLWQHRYEEYLTDSTMLYRAMVDKEERNMKFQELYEKYKHMLYDASEFEQTQRDPDDVFSEACVIYQIVYEKARWSNDASRCGFAWKVAGRALCHFYALKNEGDTALCSLPLLR
What is the function of this protein?
Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs).
What are the official names of this protein?
Probable RNA-dependent RNA polymerase 3, OsRDR3.
What is the protein family that this protein belongs to?
Belongs to the RdRP family.
Protein: EST1_CULPI
Sequence: MSLESLTVQTKYGPVRGKRNVSLLGQEYVSFQGIPYARAPEGELRFKAPVPPQKWTETLDCTQQCEPCYHFDRRLQKIVGCEDSLKINVFAKEINPSTPLPVMLYIYGGGFTEGTSGTELYGPDFLVQKDIVLVSFNYRIGALGFLCCQSEQDGVPGNAGLKDQNLAIRWVLENIAAFGGDPKRVTLAGHSAGAASVQYHLISDASKDLFQRRIVMSGSTYSSWSLTRQRNWVEKLAKAIGWDGQGGESGALRFLRRAKPEDIVAHQEKLLTDQDMQDDIFTPFGPTVEPYLTEQCIIPKAPFEMARTAWGDKIDIMIGGTSEEGLLLLQKIKLHPELLSHPHLFLGNVPPNLKISMEKRIEFAAKLKQRYYPDSIPSMENNLGYVHMMSDRVFWHGLHRTILARAARSRARTFVYRICLDSEFYNHYRIMMIDPKLRGTAHADELSYLFSNFTQQVPGKETFEYRGLQTLVDVFSAFVINGDPNCGMTAKGGVVFEPNAQTKPTFKCLNIANDGVAFVDYPDADRLDMWDAMYVNDELF
What is the function of this protein?
Overproduction of nonspecific esterases is a common mechanism of resistance to organophosphate insecticides.
What are the official names of this protein?
Esterase B1.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
Protein: HTRA2_DROYA
Sequence: MALRGSHRLEVIFKRCIASPVFHSHAANRRSSQLAIKGTDPSSNGNSGQDQQNGEQKAKGWRRLVRFFVPFSLGAAVSAAVIKREDFTPTIAASKMTGRRRDFNFIADVVAGCADSVVYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNNLSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSHLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKNLDIVILRGVKQMHVTITPEDP
What is the function of this protein?
Serine protease that shows proteolytic activity against a non-specific substrate beta-casein.  Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism.  Can antagonize antiapoptotic activity of th by directly inducing the degradation of th (By similarity).
What are the official names of this protein?
Serine protease HTRA2, mitochondrial, High temperature requirement protein A2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Note=Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment. The extramitochondrial protein does not diffuse throughout the cytosol but stays near the mitochondria.
Protein: EPRA1_AERHY
Sequence: MMKATPIALLLAGVLASPLCAAGLDARLTLVEGSTDDVRVNLTLTNTGEKPVRLLKWQLPGSEDAPLFQVERDGQPVDYEGALIKRAAPSDKDYQLLKAGQSLTVQAEVSGLYDMSAQGQYSIRYLLPTVAQEGKAAKAKQAQASESNAVTLWVDGVSDDRVLAKAAVAEPQAVSASVSFSGRCTNTQKSDILAALDAASGIANNSSSYLAVDKPNGQRYRSWFGAYDATRWNQAETNFSKIKDAIDNKPLTFDCGCKQSYFAYVYPDQPYKVYLCKSFWTAPVTGTDSRAGTIVHELSHFNVVAGTDDLGYGQANARNLASTDPQKALNNADNHEYFAENTPSEN
What is the function of this protein?
Heat-labile protease.
What are the official names of this protein?
Extracellular protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase M35 family.
Protein: AGRA3_MOUSE
Sequence: MEPPPPLLLLPLALLALLWGGERGAAALPAGCKHDGRARGTGRAAAAAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSGLSLLERLDLRNNLISRIAPGAFWGLSSLKRLDLTNNRIGCLNADVFRGLTNLVRLNLSGNLFTSLSQGTFDYLGSLRSLEFQTEYLLCDCNILWMHRWVKERNITVRDTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLPFQCMASYIDQDMQVLWYQDGRIVETDESQGIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNTHSSGIYPGSAQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLTNAVATARQLLAYTVEAANFSDKMDVIFVAEMIEKFGRFTREEKSKELGDVMVDVASNIMLADERVLWLAQREAKACSRIVQCLQRIATHRLASGAHVYSTYSPNIALEAYVIKAAGFTGMTCSVFQKVAASDRAGLSDYGRRDPDGNLDKQLSFKCNVSSTFSSLALKNTIMEASIQLPSSLLSPKHKREARAADDALYKLQLIAFRNGKLFPATGNSTKLADDGKRRTVVTPVILTKIDGATVDTHHIPVNVTLRRIAHGADAVAAQWDFDLLNGQGGWKSDGCCILYSDENITTIQCGSLGNYAVLMDLTGTELYTPAASLLHPVVYTTAITLLLCLLAVIISYMYHHSLIRISLKSWHMLVNLCFHILLTCVVFVGGITQTRNASVCQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKRCQDPDEPPAPPRPMLRFYLIGGGIPIIVCGITAAANIKNYGSRPSAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAANENGEINHQDSMSLSLISTSTLENEHSFQSQLLGASLTLLLYVILWMFGAMAVSLYYPLDLVFSFFFGATCLSFSAFMMVHHCINREDVRLAWIMMCCPGRSSYSVQVNVQPPNSSATNGEAPKCTNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQYHSNALPVNATPQLDNSLTEHSMDNDIKMHVAPLDVQFRTNVHPSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSVQNGLPKSRPGSNEGHSRSRRAYLAYRERQYNPPQQDSSDACSTLPKSSRNVEKPVSTSSKKDAPRKPAAADLESQQKSYGLNLAVQNGPVKSNGQEGPLLATDVTGNVRTGLWKHETTV
What is the function of this protein?
Orphan receptor that may have a role in planar cell polarity pathway.
What are the official names of this protein?
Adhesion G protein-coupled receptor A3, G-protein coupled receptor 125.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: DMTF1_HUMAN
Sequence: MSTVEEDSDTVTVETVNSVTLTQDTEGNLILHCPQNEADEIDSEDSIEPPHKRLCLSSEDDQSIDDSTPCISVVALPLSENDQSFEVTMTATTEVADDEVTEGTVTQIQILQNEQLDEISPLGNEEVSAVSQAWFTTKEDKDSLTNKGHKWKQGMWSKEEIDILMNNIERYLKARGIKDATEIIFEMSKDERKDFYRTIAWGLNRPLFAVYRRVLRMYDDRNHVGKYTPEEIEKLKELRIKHGNDWATIGAALGRSASSVKDRCRLMKDTCNTGKWTEEEEKRLAEVVHELTSTEPGDIVTQGVSWAAVAERVGTRSEKQCRSKWLNYLNWKQSGGTEWTKEDEINLILRIAELDVADENDINWDLLAEGWSSVRSPQWLRSKWWTIKRQIANHKDVSFPVLIKGLKQLHENQKNNPTLLENKSGSGVPNSNTNSSVQHVQIRVARLEDNTAISSSPMAALQIPVQITHVSSADSPATVDSETITLNSGTLQTFEILPSFHLQPTGTPGTYLLQTSSSQGLPLTLTASPTVTLTAAAPASPEQIIVHALSPEHLLNTSDNVTVQCHTPRVIIQTVATEDITSSISQAELTVDSDIQSSDFPEPPDALEADTFPDEIHHPKMTVEPSFNDAHVSKFSDQNSTELMNSVMVRTEEEISDTDLKQEESPSDLASAYVTEGLESPTIEEQVDQTIDDETILIVPSPHGFIQASDVIDTESVLPLTTLTDPILQHHQEESNIIGSSLGSPVSEDSKDVEDLVNCH
What is the function of this protein?
Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity).  Binds to the consensus sequence 5'-CCCG[GT]ATGT-3' (By similarity).  Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene.  Isoform 2 may antagonize transcriptional activation by isoform 1.
What are the official names of this protein?
Cyclin-D-binding Myb-like transcription factor 1, hDMTF1, Cyclin-D-interacting Myb-like protein 1, hDMP1.
What is the protein family that this protein belongs to?
Belongs to the DMTF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DDL_ACET2
Sequence: MGDKKRVLVIFGGQSSEHEVSRISATSILKNINLDKFDVSMIGITKDGKWLYYDGPIDKIPSGEWEEIALKDGTRSIADRVSLFDNIISCKNNACGLEKASENEKSKKIDVVFPVLHGCNGEDGTIQGLFELAGIPYVGCGVLASAVGMDKIYAKIIFEKAGIPQADYLYFTRKEIYGDVEGVVDKIEEKFSYPVFVKPSNAGSSVGVSKAHDKNELKEALIYAARYDRKVLIEEFINGREVECAVLGNDDPVASTVGEIIPGNEFYDYKAKYIENTSKIKIPADLPEETVEQIRNYAVKAFKALDCSGLARVDFFVHKETGKVYINEINTMPGFTSISMYPMLWEESGISYPELIEKLIDLAVQRYNDNLKEYDE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS2_MYCBO
Sequence: MPARRSAARIDFAGSPRPTLGVEWEFALVDSQTRDLSNEATAVIAEIGENPRVHKELLRNTVEIVSGICECTAEAMQDLRDTLGPARQIVRDRGMELFCAGTHPFARWSAQKLTDAPRYAELIKRTQWWGRQMLIWGVHVHVGIRSAHKVMPIMTSLLNYYPHLLALSASSPWWGGEDTGYASNRAMMFQQLPTAGLPFHFQRWAEFEGFVYDQKKTGIIDHMDEIRWDIRPSPHLGTLEVRICDGVSNLRELGALVALTHCLIVDLDRRLDAGETLPTMPPWHVQENKWRAARYGLDAVIILDADSNERLVTDDLADVLTRLEPVAKSLNCADELAAVSDIYRDGASYQRQLRVAQQHDGDLRAVVDALVAELVI
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: RL18A_PYRCJ
Sequence: MPKIYRVVGDTSTGMKFVVEVVGERPYDALEKVYSVLGSRHKLKRTQIRIREVSVVEPSSAKSNEAKMLMVLEKVVRY
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: GPI14_CANGA
Sequence: MFKLGTIGLLSLAVLLRIAFFLFGVYQDEHFTVKYTDIDYQVFNDAAWFVAHRKSPYNRDTYRYTPLLSWLLLPNHMIPWFHFGKLIFVLCDLATGVLILQMLKKLKSKYRYGTDRMTIMAAIWLLNPMVITISTRGNAESVLCFLILSFLYCFLCEQYLLGGLLFGLSIHFKIYPIIYALPIAIYVAAAHYNKTQSVFKSSFKLFLVGFSTLIVLILLTVFMYMLYGDKFIDQTYLYHIYRTDHRHNFSVWNMLLYFNSALPKTSELSKFVFLPQMIIVLAISLTQLRRPSSFPLLCNVLFLETFAFVTFNKVCTSQYFIWYLIFLPFVLYNTRISMRRGIVMLVVWVATQALWLRQGYLLEFEGQNVFYPGLFCASVGFFVSNAWILGQFIEDTIIQNDYVYRIEPSESRSKDSAVIDKPAIAKTEKAE
What is the function of this protein?
Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.  Required for cell wall integrity (By similarity).
What are the official names of this protein?
GPI mannosyltransferase 1, GPI mannosyltransferase I, GPI-MT-I, Glycosylphosphatidylinositol-anchor biosynthesis protein 14.
What is the protein family that this protein belongs to?
Belongs to the PIGM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KCAB1_HUMAN
Sequence: MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
What is the function of this protein?
Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits (PubMed:7499366, PubMed:7603988, PubMed:17156368, PubMed:17540341, PubMed:19713757).  Modulates action potentials via its effect on the pore-forming alpha subunits (By similarity).  Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity (By similarity).  Mediates closure of delayed rectifier potassium channels by physically obstructing the pore via its N-terminal domain and increases the speed of channel closure for other family members (PubMed:9763623).  Promotes the closure of KCNA1, KCNA2 and KCNA5 channels (PubMed:7499366, PubMed:7890032, PubMed:7603988, PubMed:7649300, PubMed:8938711, PubMed:12077175, PubMed:12130714, PubMed:15361858, PubMed:17540341, PubMed:19713757).  Accelerates KCNA4 channel closure (PubMed:7890032, PubMed:7649300, PubMed:7890764, PubMed:9763623).  Accelerates the closure of heteromeric channels formed by KCNA1 and KCNA4 (PubMed:17156368).  Accelerates the closure of heteromeric channels formed by KCNA2, KCNA5 and KCNA6 (By similarity).  Isoform KvB1. 2 has no effect on KCNA1, KCNA2 or KCNB1 (PubMed:7890032, PubMed:7890764).  Enhances KCNB1 and KCNB2 channel activity (By similarity).  Binds NADPH; this is required for efficient down-regulation of potassium channel activity (PubMed:17540341).  Has NADPH-dependent aldoketoreductase activity (By similarity).  Oxidation of the bound NADPH strongly decreases N-type inactivation of potassium channel activity (By similarity).
What are the official names of this protein?
Voltage-gated potassium channel subunit beta-1, K(+) channel subunit beta-1, Kv-beta-1.
What is the protein family that this protein belongs to?
Belongs to the shaker potassium channel beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Recruited to the cytoplasmic side of the cell membrane via its interaction with pore-forming potassium channel alpha subunits.
Protein: BIOF_ACAM1
Sequence: MAAYDWIESALATVHKANWYRSVKTMSSPGPTAVLNGQTVINFASNDYLGLAGDSRLAEAAIAAINTYGTGSTGSRLLSGHRMIHEQLERAIATWKQTETAIVYSSGYLANIGTITALVNKRDLILADAYNHASLKNGARLSGATIHEFGHANVTELQTLLETHRSHHRRCLLVTDSVFSMDGDLCPLPELIALAEQYDCMLLIDEAHGTGVLGKTGAGCVEHFGCRDAELIQMGTLSKALGSLGGYVAGSASLIDYLRNRSSSWIYTTGLSPADTAAALAAVEIIREGSELRSQLWQRVTQLKQALTTHLAPEDEHQTMQLLPSESPILCVQMPTPAAVLTASQQLLDQGIFAPAIRPPTVPTSRIRISIMATHQAVQIDQLIVALSEVAQGS
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
Putative 8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: PSBJ_PROMS
Sequence: MSKLKGPDGRIPDRLPDGRPAVAWERRWTEGTLPLWLVATAGGIAVIFVLGIFFYGSYQGVGAGG
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PSBX_PROMA
Sequence: MAFTLLFGAGVSGDVATASAVGMIGSFLAAAALIVVPAASFLLWVSQKDALERGR
What is the function of this protein?
Involved in the binding and/or turnover of quinones at the Q(B) site of Photosystem II.
What are the official names of this protein?
Photosystem II reaction center X protein.
What is the protein family that this protein belongs to?
Belongs to the PsbX family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: DPHB_METM7
Sequence: MLVMAGLGLYDERDVTLKTLDFAKKVDKIYAEFYTAILTGTSMEKIENTLQKPITVLDREKVEYETNKLIEEAVDKDIMFLTAGDPMVATTHVDIAVEARKKGIEVVIINAPSIYSAIGITGLQLYKFGKTTSVVFPEPNYFPETPYDVIKDNLKLGYHTLCLLDIQADKERFMTANEGLDALLKIEEKRNENVISGETYAAVVARAGSIKPGLYYGKIKDLINYDFGTPLHCVIIPGKLHFMEEDALKYLFENI
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine.  The three successive methylation reactions represent the second step of diphthamide biosynthesis.
What are the official names of this protein?
Diphthine synthase, Diphthamide biosynthesis methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the diphthine synthase family.
Protein: RL30_CLOK5
Sequence: MAKLKITLKKSLIGRKKDHIATVNALGLKKIGKVVEHEDNPQIKGMIKKVSYLLEVEEV
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SLYD_HAEIN
Sequence: MKVEKNVVVSISYQVRTQDGVLVDEAPANQPLEYLQGHNNLVIGLEKALEGKEVGDKFEVRVQPEEGYGAYSENMVQRVPKDVFQGVDELEVGMRFLADTDIGPVPVVITEIDGDEVVVDGNHMLAGQELHFTVEVVAAREATLEEIAHGHVHGAHSHDDDEEGHGCGCGGHHHEHNHEHNHGSCGCGGH
What is the function of this protein?
Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step.  This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity (By similarity).
What are the official names of this protein?
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD, PPIase, Metallochaperone SlyD.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMD_BRADU
Sequence: MIMSLGPYASFIVTSYAAAALVVAILIGWIATDYRSQTRRLRDLDRSGITRRSGRSAMDRP
What is the function of this protein?
Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.
What are the official names of this protein?
Heme exporter protein D, Cytochrome c-type biogenesis protein CycX.
What is the protein family that this protein belongs to?
Belongs to the CcmD/CycX/HelD family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YCF3_THAPS
Sequence: MGVRNFIDRVFTVISDLILKLLPASKQEKQAFAYYKAGMAAQAEGDYAEALENYYESLYLDEDQYDRSYTLYNIGLIYAKNENYPRALEYYHQAVSLNSNLPQALNNIAAIYHRQGLLALEMASQDYDAEMEISEEYEYIELAKGLFDKAAEYWYQALKLAPDNYPRARNWLRITGRAKSLDSF
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: SCAF_HHV8P
Sequence: MAQGLYVGGFVDVVSCPKLEQELYLDPDQVTDYLPVTEPLPITIEHLPETEVGWTLGLFQVSHGIFCTGAITSPAFLELASRLADTSHVARAPVKNLPKEPLLEILHTWLPGLSLSSIHPRELSQTPSGPVFQHVSLCALGRRRGTVAVYGHDAEWVVSRFSSVSKSERAHILQHVSSCRLEDLSTPNFVSPLETLMAKAIDASFIRDRLDLLKTDRGVASILSPAYLKASQFPVGIQAVTPPRPAMNSSGQEDIISIPKSAFLSMLQSSIDGMKTTAAKMSHTLSGPGLMGCGGQMFPTDHHLPSYVSNPAPPYGYAYKNPYDPWYYSPQLPGYRTGKRKRGAEDDEGHLFPGEEPAYHKDILSMSKNIAEIQSELKEMKLNGWHAGPPPSSSAAAAAVDPHYRPHANSAAPCQFPTMKEHGGTYVHPPIYVQAPHGQFQQAAPILFAQPHVSHPPVSTGLAVVGAPPAEPTPASSTQSIQQQAPETTHTPCAAVEKDAPTPNPTSNRVEASSRSSPKSKIRKMFCEELLNKQ
What is the function of this protein?
Plays a major role in capsid assembly.  Acts as a scaffold protein by binding major capsid protein.  Multimerizes in the nucleus such as major capsid protein forms the icosahedral T=16 capsid.  Cleaved by assemblin after capsid completion.  The cleavages products are evicted from the capsid before or during DNA packaging.
What are the official names of this protein?
Capsid scaffolding protein, Capsid protein P40, Protease precursor, pPR.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae capsid scaffolding protein family.
What are the subcellular locations of this protein?
[Capsid scaffolding protein]: Host cytoplasm. SUBCELLULAR LOCATION: [Assemblin]: Host nucleus. SUBCELLULAR LOCATION: [Assembly protein]: Host nucleus.
Protein: NIP7_DICDI
Sequence: MRPMTEEESKTFFEKLIKFIGKNVTLLIQRKDEPYCFRIQKNKVYYVSEELMKRSQNIPREGLCSLGTCFGRFTKTGKFKLNITCLDYLAQYAKYKVWVKPSSEMSWMYGNNLLKAGLGRITEDTPANQGVVLFSMNDVPIGFGVTSKSTHECRKLDPQALVVYHYGDVGEYLRDEDIM
What is the function of this protein?
Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
What are the official names of this protein?
60S ribosome subunit biogenesis protein NIP7 homolog.
What is the protein family that this protein belongs to?
Belongs to the NIP7 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MOBA_STAA2
Sequence: MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_XANP2
Sequence: MALAAELIRAPSVTPHADDALELVAKRLEAAGYRVERLTFETGGVPIPNLYARIGTDGPNLCFAGHVDVVPEGDATQWHHAPFAGTVEDGVLHGRGAVDMKGAVAAFLAAALAFGRPQRGSLSFLITGDEEGPALDGTVKVVEWLKARGETIDHCVLGEPTNPDALGDAFKVGRRGSLSGILTVKGVQGHVAYPHLADNPIPRLLKLIGDLTAAPLDHGSDFFPPSNLEVVSVDVGNPVFNLIPAQATARFNVRFNDLFSLESLKSEIIRRLDGAGLTYDLAFQTGASQSFLTAPGPFTDLVASAVEEVTGRRPEPSTSGGTSDARFIKDICPVVEFGLVGRTMHKVDEATPVKDIEALTAIYGRIIARYFSTFA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RL29_LEUMM
Sequence: MAKASELKELSLADLQKREAEFKEELFNLRFQLATGQLENTARIAQVRKDIARVKTVIRAQELANANK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: NUOD_MYCSK
Sequence: MTTPPGPPNAGGDARTGTDTVIVVGGEDWEQVVAAAEQAQAGERIVVNMGPQHPSTHGVLRLILEIEGETITEARCGIGYLHTGIEKNLEYRNWTQGVTFVTRMDYLSPFFNETAYCLGVEKLLGVTDAIPERVNVIRVMLMELNRISSHLVALATGGMELGAMSAMFYGFREREEILSVFEMITGLRMNHAYIRPGGLAADLPDGAVPRIRELLALLPGRLRDLENLLNENYIWKARTQGIGYLDLAGCMALGITGPVLRSTGLPHDLRRAQPYCGYEDYEFDVITDDGCDAYGRYLIRVKEMRESLKIVEQCVDRLKPGPVMIADKKLAWPADLELGPDGLGNSPAHIARIMGQSMEGLIHHFKLVTEGIRVPAGQVYTAVESPRGELGVHMVSDGGTRPYRVHYRDPSFTNLQAVAAMCEGGMVADAISAVASIDPVMGGVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.