PharMolix/UniProtQA huggingface dataset:
Protein: HIS6_ALKMQ
Sequence: MITKRIIPCLDVRKGRVVKGVNFVDIKDAGDPVALARAYNDQGADEIVFLDITASHEERYILLDVVKKTSEEIFIPLTVGGGIRTVEDMRQIIKSGADKVSINSSAVKNPSMITDCARQFGSQAVVIAMDVKRGADGRYEVYVRGGREKTGLEAVDWARRVAQLGAGEILLTSMDRDGTKSGYDLEITKRISQAVNIPVIASGGAGSVQDFADAFIEGQADAALAASLFHYNEVSIPRLKQSLHEMDISMRR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIP4L_ORYSJ
Sequence: MKISELSPEYREPPSHAGLIADLSKAVSDVESFAASATAPEKLAADLRRILTSLASAASSSSFTESLSVQIWRLGTRLWNAVVDRANSAALAGGPAALAVEAEIRQAAPELLLLAGIPNGVPSAAAKVASFFHRSGLAWLDLGRVDLASACFEKATPLVSAAATEDRGVLLELNLARARAASDAGDQALAVALLSRSKPLAAASPEGAKSLAQGYLSIGEATLAAKHSNPAVEASTLFTEALDLCEKAASPSSSSPRTPPYGGATPKTPNLEGLKRRCLRFLALERLQAQDYEGVLRCIRVSRASMGLEEEHPSIGVMAMRAWIGSGNMAEADKELERLMANALATENLCVSAAEAYLAAAGPEAARKVLIALAARCRAGGAAAAVRVVKQVIDGGGGGIGRARAIAELVSDERVVALFDGPGNTHERGTMHALLWNCGTEHFRAKNYDTSADLIERSMLYVSRDEESRSRRADCFRVLSICHIALQHLDRALEFVNEAYKVEPNIKCAFLKVKINLQKGEEDEAFKQMKTMVGCVDFNPEFLTLTAHEAMSCKSFGVAVASLSYLLGLYSAERPMPMPEVAVLRNLIELLSREPGTEAEILKYSRRAKQRMADLGVESFFGSGIVGGRELNWFADLSWNMGLRASKEKKYNFGAEFFELAAEFFSSRNAECDENRSKVCKALIMAVTIMLNAEELNNSPLSDSDIKKGVEMLSRAGKLLPLISPSVPVASDQLEANNFLYLHTFNSYQLMGRMGTPAHPQQLQLIKNFASSKACTPANLLTLGVTASKGALPNMLAAEFSLKACITTALASQSPNYRVISCALRKLACLAGLQDLNGSKSDAAYDVFQQAYQIVVGLKEGEYPVEEGQWLVATAWNMSCLPLRLHQAKVARKWMKMGLDLARHLEGMKERIASMQTTFENFERVSGDEPDECSQEEAPKASISGSMSQPVLV
What is the function of this protein?
Required for crossover formation, complete synapsis of homologous chromosomes and bivalent formation during meiosis.  Is specific to recombination events resulting in interference-sensitive crossovers (class I meiotic crossover) and works cooperatively with MER3 to promote crossovers.
What are the official names of this protein?
TPR repeat-containing protein ZIP4, Protein ZIP4 homolog, OsZIP4.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Detected in punctuate foci onto the chromosomes in prophase I meiocytes.
Protein: ENOPH_AEDAE
Sequence: MAAVSFDEKVLAAKKIICDIEGTTSSISFVKDVLFPYALKHVEEYLKNHWSEDATKTVVAALREQADEDKKAEVEGVVTIPAGDSEDIIPDVVKNVEWQMSQDRKTGALKTLQGLVWAKGYKDGTIKGHVYEDVKKALEQWNESGRKVYIYSSGSVDAQKLLFEHSEQGDLIKYVAGYYDTKIGAKQEKNSYEAILKNIEATGEEALFLTDVVAEAKAAKDAGLNVVVLDRPGNAELSEEDRKEFTVISSFTDLPIESVKSTETENGAEKETVTESTEKVADESEKETETETAAAETENGAEAENGASKRKIDETAQDDEAQRPSKVVKVDQNGDSPAVDGAKQNGDSAEEPATLSETNGKSTGEDAMDVDAEMTDVESSSTTKAAEAGTGKVTEKTETEESPKEKETEMEAEAEVSKTDEKEDTKQQGESVTDGEDKKGDVINKNAEDDIKVEEEKNKEEESAPPTKKAKIEEDKMDVDEEDSAVIEKKADNVDEKPVESTTDEVAKKEENLVETPVDTAKPEVTTSEIAVTDETKEAPSDAAKEESVTSTSKTEEEKSDDLVPTTTSEQTVEKSSAEKTESKSEEETDSGTSEKKVEDKSANNEEEQKEPKESVVAEKKEEEIKVKTADEETKSMETDEVTVEKSNTKEVKDDNEQIPDSKADQDFNAKEAAKETVSEELEVKADAIVPADESKPKAQNDETKEKVTKAEEVTKTAETKTEEEEAKKTEEDAKKTEEDAKKTEKEVKKTDEEMPTEEIKMKDEPTVPEKSKSVDEPMATEESVATKEETLAEETSATTEAQATKEDEKPVDTKTNENDKTTPEVKATEEKTDDAKSTEVATATEEDKEMKEANSAEESVETKEKKTEETHTTDEDKPKESDVAKPDVVEKQEEKMETSEQVDETKGVEATTAGPVEEVAVEATEEDVAMEAESSDAVKEETKTEEPKSKVDKLDSEAMEVDSASTSQNEAKNESVKPAETAAVEESKTESDVVSTTSTDEVKENGTSEKVNTKEESRVPENGEADSKVTTNGNHDEKADSDKENDTSASNIEEASSATTTTTNGTSTESDSSSTTPSSETVAEIKSKKATDAVADSATPSVETES
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YXEQ_BACSU
Sequence: MSKQGLTAGLAEAVRTSQPEHSVDAIHEAKKGLLDFTAASFAGREDKGIQKLLRLIEDEGGRPLVPVIGQGKKAAPLQSAMLNGFIAHALDFDDVHSDVRGHPSAVIVPALIASAARGHDERLLGAYVVGVEVMARLGESIGSRHYEKGWHNTGTLGAIAAACAVGYAEELTQEELEKAIGFAATQSAGMRVQFGTEMKPLHAGLAAQAGLLAVKLAQSEFGGSRTALDGETGFFSLYGDVEKAQHTLLNDWGAPWRIVQPGLWFKIYPFCSAAHHAADAVRQLISEETISAANTERIEVIFPPGGDAALTERSPKAGEEGRFSVEYVIALALHGHGLTVEHFSSQPIPNGVQTTMGRIQRVYDNAIQPAPHAVPKGRFTIVRAYLSDGRICEARVDCPKGAPGNELSEEDIIEKLTLTVPQEKARRIITAVEKADIKEFLAHIE
What are the official names of this protein?
Uncharacterized protein YxeQ.
What is the protein family that this protein belongs to?
Belongs to the PrpD family.
Protein: AOC1_MOUSE
Sequence: MSLAFGWAAVILLLQTADTASAVTTPHDKARIFADLSPQEIKAVHSFLMSRKELGLESSKNLTLAKNSVFLIEMLLPKKKNVLKFLDEGRKSPVREARAIIFFGAQDHPNVTEFAVGPLPRPCYVQALSPRPGHHLSWSSRPISTAEYDLLYHMLNRAITPLHQFFLDTTGFSFLGCDDRFLTFTDVAPRGVESGQRRSWLIVQRYVEGYFLHPTGLEILVDHSSTDVQDWRVEQLWYNGKFYNSPEELAQKYAVGEVEAVVLEEVVLEDPLPGATEQPPLFSSYKPRGEFHTPVTVAGPHVVQPSGPRYKLEGNVVLYGDWSFSYRLRSSSGLQIFNVLFGGERVAYEVSVQEAVALYGGHTPAGMQTKYIDVGWGLGSVTHELAPGIDCPETATFLDAFHYYDSDGPVLYPRALCLFEMPTGVPLRRHFDSNFKGGFNFYAGLKGYVLVLRTTSTVYNYDYIWDFIFYPNGVMETKMHATGYVHATFYTPEGLRHGTRLQTHLLGNIHTHLVHYRVDLDVAGTKNSFRTLKTKLENITNPWSPSHSLVQPTLEQTQYSHEHQAAFRFGQTLPKYLLFSSPQKNRWGHRRSYRLQIHSMAEQVLPPGWQEERAVTWARYPLAVTKYRESERYSSSLYNQNDPWDPPVVFEEFLRNNENIENEDLVAWVTVGFLHIPHSEDVPNTATPGNCVGFLIRPFNFFEEDPSLASRDTVIVWPQDNGLNHVQRWIPENRDCLVSPPFSYNGTYKPV
What is the function of this protein?
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis.
What are the official names of this protein?
Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: ISPDF_CHESB
Sequence: MNAPFEKDRRNRRVAVVVVAAGRGERAGQAQNGPKQYRLIGGKPVIRHTLEVLAKSKRVGTIAVAVHPEDSSLFNQAREGLDGDIRAVHGGASRQESTRLALAALEEVKPDIVLIHDGVRPFIDEALIERVIEAVGEDSGALPALPVSDTLKRSGVNGIITGTVPRDGLFAAQTPQGFPFRPIYEAHQKAWQSGRSDFTDDAAIAEWAGISVRLVSGSPDNVKLTWAKDIALADQRLGPAMTELPDIRVGNGYDVHGFGPGGHVTLCGVQIPHGKTLMGHSDADVGLHALTDALLATCGAGDIGTHFPPSDPQWKGAKSRIFVEHAVNLLRARGGRIANADVTLICEAPRIGPYREAMLAELSDMLQISPERVSVKATTNEGLGFIGRAEGIAAIATATVAYPGSLGN
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: COBD_LISMO
Sequence: MILLFYTSSFILDCLLGDPYSWPHPIKAIGNLIKWLTIILRKIFHGKSLYFAGGLLFVLTVGMTGAVSWFILFLSAKIAYWLYVAVFVYLGYTTLAMTCLAKEARKIQRTLADGDLAAARVQVGMIVGRDTDKLTAEEISKATIETVAENTADGVIAPLFYLFIGGPVLALMYKAVNTLDSMVGYKNEKYRAIGFVSAKMDDIANFIPARLAWFFLVIASFILRYDGRASWQIGLRDRKNHTSPNCAYPEGAVAGALGITLGGTHEYFGETVVKPTIGSGTKPVSEKEISQTIHLLYMASTIAFIMFASIYLLLF
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
What are the official names of this protein?
Cobalamin biosynthesis protein CobD.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LACA1_STRPQ
Sequence: MAIILGADAHGNALKELIKSFLQEESYDIIDVTDINSDFIDNTLAVAKAVNEAEGRLGIMVDAYGAGPFMVATKLKGMVAAEVSDERSAYMTRGHNNARMITIGAEIVGPELAKNIVKGFVTGPYDGGRHQIRVDMLNKMA
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacA 1.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: CALR3_MOUSE
Sequence: MVSARALLWAICVLRVALATVYFQEEFLDGERWRNRWVQSTNDSQFGHFRVSSGKFYGHKEKDKGLQTTQNSRFYAISASFKPFSNKGKTLVIQYTVKHEQKMDCGGGYIKVFPSDLDQKKMNGKSQYYIMFGPDICGFDIKKVHVILYFKNQYHENKKPIRCKVDGFTHLYTLILRPDLSYEVKVDGQSIESGSIEYDWNLTSLRKTEKTSLDSRDWDQVEGSKVQDWEKHFLDAGASKPSDWNSELDGDWLQKPPYEDGLKAEGIDKDVWLHQKMRPAGYLTQYDLSEFENIGAIGLELWQVRSGTIFDNFLITDDEEYAEKFGKATWGETKGPEKEMDAIQAKEEVKKAREEDEEDLLMGKFHRHNHFSRFHRQGEL
What is the function of this protein?
CALR3 capacity for calcium-binding may be absent or much lower than that of CALR (By similarity).  During spermatogenesis, may act as a lectin-independent chaperone for specific client proteins such as ADAM3.  Required for sperm fertility.
What are the official names of this protein?
Calreticulin-3, Calreticulin-2, Calsperin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: DLDH_MANSE
Sequence: MGYKFLKLASASFRNGGVRIVSRQYSTTHDADLVVIGAGPGGYVAAIKAAQLGMKVVSVEKEPSLGGTCLNVGCIPSKALLHNTHLYHMAKHDFKHRGIETGEVKFNFKAMMDYKVNAVKALTGGIAMLFQKNKVKLVRGAGTIVAPNKVEVKGEKGVETVNTKNILIATGSEVTPFPGVTFDEKQIITSTGALSLESVPKKMLVIGAGVIGLELGSVYQRLGADVTAIEFLGSIGGIGIDMEVSKDYRILAKQGMKFKLETKVLGVKKEGSTVKVEDVSIEGAKGGNKETMDCDVVLISIGRRPYTKDLGLDKVGIALDDRGRVPVNNKFQTTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVRKTEEDLKKEGKAYKVRKFPFLANSRAKTNGEPDGFVKVLSDKATDVILGTHIIGPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYCGKPINF
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, Dihydrolipoamide dehydrogenase, E3.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAP9_ORYSJ
Sequence: MAQESWKNESEETVHTPEAPILCVNNCGFFGSSMTNNMCSKCYRDFVKVTTMAAPVVEKKAFTPASSSKTPLEPAKPDEVPAAAVEDKQAAQEPPKPPSNRCLSCRKKVGLTGFQCRCGGTFCSTHRYTEAHDCTFDYKKAGRDQIAKQNPVVIAEKINKI
What is the function of this protein?
May be involved in environmental stress response.
What are the official names of this protein?
Zinc finger A20 and AN1 domain-containing stress-associated protein 9, OsSAP9.
Protein: FABP4_RAT
Sequence: MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNLIISVEGDLVVIRSESTFKNTEISFKLGVEFDEITPDDRKVKSIITLDGGVLVHVQKWDGKSTTIKKRRDGDKLVVECVMKGVTSTRVYERA
What is the function of this protein?
Lipid transport protein in adipocytes.  Binds both long chain fatty acids and retinoic acid.  Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
What are the official names of this protein?
Fatty acid-binding protein, adipocyte, Adipocyte lipid-binding protein, ALBP, Adipocyte-type fatty acid-binding protein, A-FABP, AFABP, Fatty acid-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Protein: FBXW9_HUMAN
Sequence: MELPLGRCDDSRTWDDDSDPESETDPDAQAKAYVARVLSPPKSGLAFSRPSQLSTPAASPSASEPRAASRVSAVSEPGLLSLPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWRLRALRRVRAPYPVVEEKNFDWPAACIALEQHLSRWAEDGRWVEYFCLAEGHVASVDSVLLLQGGSLCLSGSRDRNVNLWDLRQLGTESNQVLIKTLGTKRNSTHEGWVWSLAAQDHRVCSGSWDSTVKLWDMAADGQQFGEIKASSAVLCLSYLPDILVTGTYDKKVTIYDPRAGPALLKHQQLHSRPVLTLLADDRHIISGSEDHTLVVVDRRANSVLQRLQLDSYLLCMSYQEPQLWAGDNQGLLHVFANRNGCFQLIRSFDVGHSFPITGIQYSVGALYTTSTDKTIRVHVPTDPPRTICTRRHDNGLNRVCAEGNLVVAGSGDLSLEVWRLQA
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box/WD repeat-containing protein 9, F-box and WD-40 domain-containing protein 9.
Protein: TRMB_STRP8
Sequence: MRVRKRKGAEKHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: Y4217_XANOR
Sequence: MLHYAMIFFVIAIIAAVLGFSGIAGAATNIAWILFVVFLILAVISMFRRGKV
What are the official names of this protein?
UPF0391 membrane protein XOO4217.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYE_STAA8
Sequence: MSDRIRVRYAPSPTGYLHIGNARTALFNYLYAKHYNGDFVIRIEDTDKKRNLEDGETSQFDNLKWLGLDWDESVDKDNGYGPYRQSERQHIYQPLIDQLLAEDKAYKCYMTEEELEAEREAQIARGEMPRYGGQHAHLTEEQRQQFEAEGRQPSIRFRVPQNQTYSFDDMVKGNISFDSNGIGDWVIVKKDGIPTYNFAVAIDDHYMQISDVIRGDDHISNTPKQIMIYEAFGWEPPRFGHMSLIVNEERKKLSKRDGQILQFIEQYRDLGYLPEALFNFIALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPAFFDKQKLAWVNNQYMKQKDTETVFQLALPHLIKANLIPEVPSEEDLSWGRKLIALYQKEMSYAGEIVPLSEMFFKEMPALGEEEQQVINGEQVPELMTHLFSKLEALEPFEAAEIKKTIKEVQKETGIKGKQLFMPIRVAVTGQMHGPELPNTIEVLGKEKVLNRLKQYK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_NEOSM
Sequence: MRRVLLKISGERLAARGVSVHDAEVIGMLARGIKRVHEMGIQVCLVIGGGNIYRGSSGIPNIDRATGDYMGMLATVINALALQGAINNLGVVSRVQSAIPMRSICEPYVRQKAISHMEKNRIVIFAAGTGNPFFTTDTAAVLRSVEMGCDVMLKGTLVDGIYSDDPRTNINAERITKLSYTDVLSKKLRVLDSSAVSIARDNGMPVVIFSLDSEMAFYEVINKQGNYSTIEGE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXAC_SALEP
Sequence: MATFMTEDFLLKNDIARTLYHKYAAPMPIYDFHCHLSPQEIADDRRFDNLGQIWLEGDHYKWRALRSAGVDESLITGKETSDYEKYMAWANTVPKTLGNPLYHWTHLELRRPFGITGTLFGPDTAESIWTQCNEKLATPAFSARGIMQQMNVRMVGTTDDPIDSLEYHRQIAADDSIDIEVAPSWRPDKVFKIELDGFVDYLRKLEAAADVSITRFDDLRQALTRRLDHFAACGCRASDHGIETLRFAPVPDDAQLDAILGKRLAGETLSELEIAQFTTAVLVWLGRQYAARGWVMQLHIGAIRNNNTRMFRLLGPDTGFDSIGDNNISWALSRLLDSMDVTNELPKTILYCLNPRDNEVLATMIGNFQGPGIAGKVQFGSGWWFNDQKDGMLRQLEQLSQMGLLSQFVGMLTDSRSFLSYTRHEYFRRILCNLLGQWAQDGEIPDDEAMLSRMVQDICFNNAQRYFTIK
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: ERH_ECHMU
Sequence: MSHTILLVQQQVKKPESRVWADYETLNQCLEGVCKIYEEQLKQQNPTAPTITYDISQLFKFIDQLADLSCLEFHPATGTYVPHTKDWIKENIYALLRNQAGQ
What is the function of this protein?
May have a role in the cell cycle.
What are the official names of this protein?
Enhancer of rudimentary homolog.
What is the protein family that this protein belongs to?
Belongs to the E(R) family.
Protein: PB2_I83A5
Sequence: MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMGMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTIHYPKVYKTYFEKVERLKRGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKREELQDCKIAPLMVAYMLERELVRKTRFLPVAGGTSSVYVEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKLRVHEGYEEFTIVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTVMSMRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSEAQGTEKLTITYSSSMMWEINGPESVLINTYQWVIRNWETVKIQWSQDPTMLYNKMEFEPFQSLVPKAARGQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKATKRLTVLGKDAGALTEDPDEGTAGVESAVLRGFLILGKEDKRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RTN1_PANTR
Sequence: MAAPGDPQDELLPLAGPGSQWLRDRGEGEDEAVTPKGATPAPQAGEPSPGLGARAREAASREAGSGPARQSPVAMETASTGVAGVSSAMDHTFSTTSKDGEGSCYTSLISDICYPPQEDSTYFTGILQRENGHVTISESPEELGTPGSSLPDVPGIESRGLFSSDSGIEMTPAESTEVNKILADPLDQMKAEAYKYIDITRPEEVKHQEQNHPELEDKDLDFKNKDTDISIKPEGVREPDEPAPVEGKIIKDHLLEESTFAPYIDDLSEEQRRAPQITTPVKITLTEIEPSVETTTQEKTPEKQDICLKPSPDTVPTVTVSEPEDDSPGSITPPSSGTEPSAAESQGKGSISEDELITAIKEAKGLSYETAESPRPVGQLADRPEVKARSGPPTIPSPLDHEASSAESGDSEIELVSEDPMAAEDALPSGYVSFGHVGGPPPSPASPSIQYSILREEREAELDSELIIESCDASSASEESPKREQDSPPMKPGALDAIREETGVRAEERAPSRRGLAEPASFLDYPSTEPQPGPELPPGDGALEPETPTLPRKPEEDASSHQSPAATKGPGPLGPGAPPPLLFLNKQKAIDLLYWRDIKQTGIVFGSFLLLLFSLTQFSVVSVVAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKAYLELEITLSQEQIQKYTDCLQFYVNSTLKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLLMAVVSMFTLPVVYVKHQAQIDQYLGLVRTHINAVVAKIQAKIPGAKRHAE
What is the function of this protein?
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity.
What are the official names of this protein?
Reticulon-1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: AMPA_METRJ
Sequence: MADGIEIGFGPLEQSGQGPGGSGDLVVFVGDDLSLGSAAREALGASGADLVARAAASEKFKGRSLSALSLPAPAGVGADRLVVVGLGSEKDRAKTDWPALGGFTASKVAGRTARVVLDWPGTTVTAAQAGEFALGARLRTYAFDRYKTKKKPDADDKSVTALTLLLADHGAAAREGEGARSLSDGVILARDLVNEPPNVLFPAEFARRASELAKLGVEIEVLEPARMRELGMGALLAVAQGSAREPRIVIMRWNGGPAAEAPVALIGKGVVFDSGGVSIKPGGGMEDMKGDMGGAAAVVGALHALAARKARCNVVGAIGIVENMPDGGAYRPSDILTSMSGQTIEVINTDAEGRLVLADVITHVIRSTKPKAIVDLATLTGAIIVALGQDIAGMFSNDDTLASNIHAAGEATGEKVWRMPLIPAYDKAIDSKFADMKNTGGRHGGAATAASFIKRYVEDVPWAHLDIAGVAMSSNASEINRSWGAGWGVRLLDRLIRDHYEAR
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_SHESR
Sequence: MAKEFSRTRRIGQQLQQELAVVLQRDMKDPRIGFVTVNDVDVSRDLSYAKVFVTFFEEDKEVVQEKLNALIAAAPYIRTLVAGRMKLRVMPEIRFVYDSSLVEGMRMSNLVSQVINSDKAKQQQFGSVDDVTENDIDEADDTEGKA
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DES8_STRVZ
Sequence: MTDDLTGALTQPPLGRTVRAVADRELGTHLLETRGIHWIHAANGDPYATVLRGQADDPYPAYERVRARGALSFSPTGSWVTADHALAASILCSTDFGVSGADGVPVPQQVLSYGEGCPLEREQVLPAAGDVPEGGQRAVVEGIHRETLEGLAPDPSASYAFELLGGFVRPAVTAAAAAVLGVPADRRADFADLLERLRPLSDSLLAPQSLRTVRAADGALAELTALLADSDDSPGALLSALGVTAAVQLTGNAVLALLAHPEQWRELCDRPGLAAAAVEETLRYDPPVQLDARVVRGETELAGRRLPAGAHVVVLTAATGRDPEVFTDPERFDLARPDAAAHLALHPAGPYGPVASLVRLQAEVALRTLAGRFPGLRQAGDVLRPRRAPVGRGPLSVPVSSS
What is the function of this protein?
Involved in the biosynthesis of the macrolide antibiotics methymycin, neomethymycin, narbomycin, and pikromycin.  DesVIII assists the folding of the DesVII polypeptide.  However, unlike chaperones, it remains bound to DesVII during catalysis, forming a tight DesVII/DesVIII complex.  Although the formation of the DesVII/DesVIII complex is essential for the catalytic activity, DesVIII is unlikely to be involved in catalysis directly.
What are the official names of this protein?
Protein DesVIII, Inactive cytochrome DesVIII.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: SYFB_PROMP
Sequence: MKVSQNWLKSLVEINTTAHDLSEKLSIGGFEVESLVDCSENVKGIVLGKVLSVVKHENSDKLSICIVDIGRSNPLQIVCGAKNVKQNIYVYVATVGTHLSAINLTIKKSEIRGVSSEGMICSLEELGIEDTSEGIAIIDEDIALNHNLGTSGAELLDLNDYIYDLAITANRPDGMSVVGIAREISALLETKLNFPGLKTRYKTNVYKNFNLCPEAISKNCLYSISNIESVNGKQLSPGWLKDRLDKSGIKSINLLVDITNYILLEQGQPLHAFDKDKLSNLIGRKVSYEDFSVRKANNNESLLCLNGENYKLNENITIIACDDKPVAIAGVIGGLETAVNEDTSSIYLEGAVFNPVIIRKSSKVIGIRTESSSRYEKGISYKNTLDSVTRAINILEEYFNITSPIINTSTELDLKKILIPLRRERIKKILGPIVIRNENYENNSKLEKRYLTDTEITEKLKLIGCTLNIKEYGWDVEIIPNRSQDLLREIDLIEEIARLIGYDMFDLNLPNPIKPGKLSSFQIALRKLKTGLIVNGFNEVLSYSLVPESKNNLIKISNPLLLETSCLRDNIWKEHINICNQNIKSGHEYCWIFEVGNIFHKKPDFSQEEILNGAIYGNNKFEQWLGSNKDNNMTYYEARGKLKEALSILNLNIEDKPTDTIDFLHPGRSSRLFTEGNEVGYFGEIHPNLISNKIALKKMYLFSLKINSILQASTRKNKWITVYKQFPTVPKMERDINFIFNKKYLVSEIISQIKKSGTKLLENVNLIDVYDDDSFGKEFISYTFRLSYRDSEKTLLDSDIGYLHDSVVEIIEKKFSTKLRD
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDCG_PSEF5
Sequence: MSGCGPWLPHDLLWGMTPAQLPGDAPAWAHAVLEAGQPVVVRRALTAPGQVAVGLRGVSREQRYPALLDLQAVQRGVRPEQLCHVPPQGPWPALQALQHLRDELDAQEWIWGVSGSAGFELASGVAALHQHSDLDLILRTPELLPRARARELLALLDGAGCPVDMQLQVPGGALALREWAGPAARVLLKSASGARLVSDPWNPQEQAA
What is the function of this protein?
Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein].
What are the official names of this protein?
Phosphoribosyl-dephospho-CoA transferase, Malonate decarboxylase holo-[acyl-carrier-protein] synthase, Holo-ACP synthase.
What is the protein family that this protein belongs to?
Belongs to the MdcG family.
Protein: LRC3B_BOVIN
Sequence: MNLVDLWLTRSLSMCLLLQSFVLMILCFHSASMCPKGCLCSSSGGLNVTCSNANLKEIPRDLPPETVLLYLDSNQITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNLKARARIANNPWHCDCTLQQVLRSMVSNHETAHNVICKTSVLDEHAGRPFLNAANDADLCNLPKKTTDYAMLVTMFGWFTMVISYVVYYVRQNQEDARRHLEYLKSLPSRQKKADEPDDISTVV
What are the official names of this protein?
Leucine-rich repeat-containing protein 3B.
What is the protein family that this protein belongs to?
Belongs to the LRRC3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.