PharMolix/UniProtQA huggingface dataset:
Protein: Y2296_YERPP
Sequence: MDHRLLEIVACPVCNGKLYFNKENLELVCKVDNLAYPVRDGIPVLLENEARPLSIDEKHA
What are the official names of this protein?
UPF0434 protein YPDSF_2296.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: MES4_CAEEL
Sequence: MLPSSGDSSKENCAPQDGIVEKEGPNKPFKKKNVKQRNATPQGAGSETSSNAEDKQEEAPILTNAPKDIISMQIQETKAFLSEYEEFVDTDYPKTTFTHVPRKFLSVSPFTPIEADAEGEFLPDADSKCVICHEEKDKTGKSDLITCHGYINGEMDDGKRLLGNIPMFPCRSKFHASCMINYNSGGFHFQYAARLECQARLLCPLHCCNSCNLDHHKQSAYVGDIAECALCLRAFHLTSCYPSGGRDLNVSITIGGKVEKFEMIICPAHYLPGADVQFYNKHKKRKNAVTVVPKADVTMKSHIKACCVIGCEKSSNSKTIMCKTCCRSFHSGCREVETLNGKPIPDDQCESCVCGDPIPQNTLILAKWTDNSFWLALTLDWYKYPTGNRGNINFERLGYTVVQWLIPQENDKEKQPLMSIVPVSDIARLTKNYFSLAKNSTLRNLWEEKYEEQADTALKRCPYVCKTVFGRLRTSVYYKCEPKLEEYHNNEVCNCEGADRCTKLSCQYLADDYECPPSCSKKGVCHNRQVSMGIVSEKIKLAATLCKGYGVFAKGQIEKDEYICEYVGEIIDKAEKKRRLDSVSISRDFQANHYMMELHKGLTVDAARYGNISRYINHSCDPNAASFVTKVFVKKTKEGSLYDTRSYIRAIRTIDDGDEITFSYNMNNEENLPDCECGAENCMGTMGKAKREKPEVADSSEKAAKKNKSSKKKSVKNQNRKSQEAGKNGTASKKSEISPSKPSTSSASSTSFVQQASWPISQNKKNLKKNSNQPVADTGSTLSTSTELNFHEKPQELLSPVSSRSRAASSSTPRAQKSKSRRDDVESEAPPVKRATPSLQTIQETGKAIEFPATKSAITKARALSTQSVPSPHTVEVKVRAISTRGRVQKETKRFEPI
What is the function of this protein?
Histone methyltransferase.  Dimethylates 'Lys-36' of histone H3, a specific tag for epigenetic transcriptional activation.  Plays a central role in early development and is responsible for all H3 'Lys-36' dimethylation until about the 40-cell stage.  Indirectly involved in the global inactivation of the X chromosomes in germline cells, possibly by excluding the mes-2-mes-3-mes-6 repressive Polycomb complex from the autosomes (PubMed:12077420, PubMed:16968818).  Not related to transcription elongation (PubMed:12077420, PubMed:16968818).  Required for small-RNA-induced H3K27 trimethylation (PubMed:26365259).  May suppress sensitivity to RNAi (PubMed:16507136).  May regulate the expression of genes required for vulval development (PubMed:16507136, PubMed:16710447).
What are the official names of this protein?
Histone-lysine N-methyltransferase mes-4, Maternal-effect sterile protein 4.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
Protein: METK1_RHORT
Sequence: MRAYCVTSESVTEGHPDKVCDQISDGILDACLAQDPAARVAVETLVSGNTVFIAGEITTTARLDAVRTAREVIEDIGYADPALGFDSGSCFILTNLRTQSPDIDLGVSRGAELGAGDQGVLYGYACDETASLMPAPIHMAHGLSLRLAAARHGGVLPWLRPDGKTQVTVRYDGEGRPEALTSVIVSTQHDEGVDRETLVRGIIEAVIYPEVGGWLKPETRVLINPTGRFVIGGPAGDTGVTGRKLMVDTYGGCARHGGGAFSGKDSTKVDRTAAYMARYAAKNVVAAGLARRCEVALAYAIGERLPEMVSVETFGTETIDVDRLTAAVRETFPFSVSGMIAALDLRRPIFRKTAAYGHFGRENKGFQWEKTDRVDALRAVCGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase 1, AdoMet synthase 1, MAT 1, Methionine adenosyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRA_SALEP
Sequence: MEIIFYHPTFNTAWWVNALEKALPHARVREWKVGDNNPADYALVWQPPVEMLAGRRLKAVFALGAGVDAILSKLNAHPEMLDASIPLFRLEDTGMGLQMQEYAVSQVLHWFRRFDDYQALKNQALWKPLPEYTREEFSVGIMGAGVLGAKVAESLQAWGFPLRCWSRSRKSWPGVESYVGREELHAFLNQTRVLINLLPNTAQTVGIINSELLDQLPDGAYVLNLARGVHVQEADLLAALDSGKLKGAMLDVFSQEPLPQESPLWRHPRVAMTPHIAAVTRPAEAIDYISRTITQLEKGEPVTGQVDRARGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU1M_MYTED
Sequence: MDWVAVIVSIIPFVGVLLAVGFYTLLERKILAIIMIRKGPSKVSYMGILQPFSDAGKLLCKEFIVPTRANVGPFILAPALMLAISLLGWLLYPYKSAEVFYVFGVILFMVITSVSVYGVMMSGWASNSKYSLLGAVRAMAQSISYEIPMGFIFFCVVLCSGVFMFQEISVFQQSLFFFFLPLCVVMLVWMLCMLAETNRAPFDFVEGESELVSGYNVEYSGGGFAVMFIAEYSSILLSSVMSAAMFFGGNEALVGFFMMVFAIFFVVVRASLPRLRYDKLMNLCWTVLLCVMLTASVCVVVLVGV
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYB_NAJKA
Sequence: MSNQHAXMXSNLLPVGSNISTWWNFGSMLLACLMLQIMTGFFLAIHYTANISLAFSSVIHITRDVPYGWIMQNLHTISASLFFICIYTHIARGLYYGLYLNKEVWLSGTALLVTLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGVTLTTWLWGGFSINDPTLTRFFALHFILPFIIISLSSVHIILLHSEGSNNPLGTNSDIDKIPFHPYHSYKDMLMITSMITLLLLILSFSPDLLNDPENFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGTLALLLSVMILTTTPFTHTSFTRSMMFRPLSQILFWTLIATFITITWTASKPVEPPFITISQTTSIFYFSFFILTPLLGWTENKMMMTNN
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SCPB_BACAA
Sequence: MDRTEQKSIIEGLLFVSGDEGIYPEQIAKVLEIEGNEVIDILEEMQKECEGAHRGLQIVQYAKVYRFATKKEHASYYQKLIEIPTAASLSQAALETLAIVAYRQPITRTEMEEIRGVKTDKALQTLVSHLLIKEMGRAEGPGRPILYGTTKEFLDTFGLKTLDDLPPLSEENEQMNEADLFFGSLQEISK
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: KN5A_ARATH
Sequence: MDSNNSKKGSSVKSPCQTPRSTEKSNRDFRVDSNSNSNPVSKNEKEKGVNIQVIVRCRPFNSEETRLQTPAVLTCNDRKKEVAVAQNIAGKQIDKTFLFDKVFGPTSQQKDLYHQAVSPIVFEVLDGYNCTIFAYGQTGTGKTYTMEGGARKKNGEIPSDAGVIPRAVKQIFDILEAQSAAEYSLKVSFLELYNEELTDLLAPEETKFADDKSKKPLALMEDGKGGVFVRGLEEEIVSTADEIYKVLEKGSAKRRTAETLLNKQSSRSHSIFSVTIHIKECTPEGEEIVKSGKLNLVDLAGSENISRSGAREGRAREAGEINKSLLTLGRVINALVEHSGHIPYRESKLTRLLRDSLGGKTKTCVIATVSPSVHCLEETLSTLDYAHRAKHIKNKPEVNQKMMKSAIMKDLYSEIERLKQEVYAAREKNGIYIPKERYTQEEAEKKAMADKIEQMEVEGEAKDKQIIDLQELYNSEQLVTAGLREKLDKTEKKLYETEQALLDLEEKHRQAVATIKEKEYLISNLLKSEKTLVDRAVELQAELANAASDVSNLFAKIGRKDKIEDSNRSLIQDFQSQLLRQLELLNNSVAGSVSQQEKQLQDMENVMVSFVSAKTKATETLRGSLAQLKEKYNTGIKSLDDIAGNLDKDSQSTLNDLNSEVTKHSCALEDMFKGFTSEAYTLLEGLQGSLHNQEEKLSAFTQQQRDLHSRSMDSAKSVSTVMLDFFKTLDTHANKLTKLAEDAQNVNEQKLSAFTKKFEESIANEEKQMLEKVAELLASSNARKKELVQIAVQDIRQGSSSQTGALQQEMSAMQDSASSIKVQWNSHIVQAESHHLDNISAVEVAKEDMQKMHLKCLENSKTGTQQWKTAQESLVDLEKRNVATADSIIRGAIENNEKLRTQFSSAVSTTLSDVDSSNREIISSIDNSLQLDKDASTDVNSTIVPCSENLKELRTHHDDNVVEIKQNTGKCLGHEYKVDEATSSTPRKREYNIPTVGSIEELKTPSFEELLKAFHDCKSPKQMQNGEAKHVSNGRPPLTAIN
What is the function of this protein?
Responsible for microtubule translocation.  May be important for the organization of phragmoplast-specific arrays of microtubules (By similarity).  Plays an essential role in stabilizing the mitotic spindle (PubMed:17652157).  Required during mitotic cytokinesis (PubMed:26745275).
What are the official names of this protein?
Kinesin-like protein KIN-5A, AtKRP125c, Protein LOOPHOLE, Protein RADIALLY SWOLLEN 7.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-5/BimC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Microtubule-associated.
Protein: SLP1_ARATH
Sequence: MASLYLNSLLPLPPSHPQKLLEPSSSSLLSTSNGNELALKPIVINGDPPTFVSAPARRIVAVGDLHGDLGKARDALQLAGVLSSDGRDQWVGQDTVLVQVGDILDRGDDEIAILSLLRSLDDQAKANGGAVFQVNGNHETMNVEGDFRYVDARAFDECTDFLDYLEDYAQDWDKAFRNWIFESRQWKEDRRSSQTYWDQWNVVKRQKGVIARSVLLRPGGRLACELSRHGVILRVNNWLFCHGGLLPHHVAYGIERINREVSTWMRSPTNYEDSPQMPFIATRGYDSVVWSRLYSRETSELEDYQIEQVNKILHDTLEAVGAKAMVVGHTPQLSGVNCEYGCGIWRVDVGMSSGVLDSRPEVLEIRGDKARVIRSNRDRLHELQVADYI
What is the function of this protein?
Shows phosphatase activity, hydrolyzing the artificial substrate para-nitrophenylphosphate (pNPP) in vitro.
What are the official names of this protein?
Shewanella-like protein phosphatase 1, AtSLP1.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. SLP family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SMG_SHIFL
Sequence: MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFEREDIYNALLWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLETREMVIERVLALDNAEFELDDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
What are the official names of this protein?
Protein Smg.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: PROQ_ECOL5
Sequence: MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRSQKPVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.  May regulate ProP activity through an RNA-based, post-transcriptional mechanism.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPMB_BUCBP
Sequence: MLNKKIKKNHKEDWITELTNAITNPDELLRTLNLKSNTKYFKNIQVQKLFSLRVPKTFVSRMKKNDPFDPLLLQILPHTKELKNNHNFVQDPLEETKNVIIPGLIRKYNNRILLLLKTNCAINCRYCFRRYFPYSQHPGNKENLNLAIQYIKNQTDLNEVILSGGDPLMAKDHEIQWIVNTLSNIYHIKRLRIHTRLPIVIPSRITNNLCKILSTTRLKILIVTHINHAQEINHELQYNINKLHKLGITLLNQSVLLRGINDNAKILSQLSNKLFDINILPYYLHILDKVKSTTHFYVSEKQASIIVVELLSMISGFLVPKLVCEHPGKNSKIYINLNMK
What is the function of this protein?
With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  EpmB appears to act before EpmA.  Displays lysine 2,3-aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity).
What are the official names of this protein?
L-lysine 2,3-aminomutase, LAM, EF-P post-translational modification enzyme B.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. KamA family.
Protein: RBSD_PSEPF
Sequence: MKKTPLLNVALSRLIASLGHGDVVVIGDAGLPVPPGVELIDLALTHGVPDFVSTLKVVLSEMQVESHALAKEIFDKQPTALSTLDELNDEGSLGRRDLLSHEQFKVLSRQARAIVRTGECQPYCNIVLVAGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_LACLA
Sequence: MISKPDKNKLRQKRHTRVRGKISGTSETPRLNVFRSNTNIYAQVIDDVTGTTLASASSLKLTGTKTEQAAEVGKLVAEAAKAKGVEEVVFDRGGYLYHGRVAALATAAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: OXLA2_DABRR
Sequence: ADDKNPLEECFCEDDDYCEG
What is the function of this protein?
Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme (PubMed:18384385).  Is active on L-Ile, L-Leu, L-Met, L-Phe, L-Trp, and L-Tyr (PubMed:18384385).  Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation.  Its effect on platelets is controversial, since it either induces aggregation or inhibits agonist-induced aggregation.  These different effects are probably due to different experimental conditions.
What are the official names of this protein?
L-amino-acid oxidase L2, LAAO-L2, LAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family. FIG1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LOG7_ARATH
Sequence: MEETKSRFKRICVFCGSSSGKKPSYQEAAIQLGNELVERRIDLVYGGGSVGLMGLVSQAVHHGGRHVLGVIPKTLMPREITGETIGEVKAVADMHQRKAEMARQADAFIALPGGYGTLEELLEVITWAQLGIHRKPVGLLNVDGYYNSLLTFIDKAVDEGFISPMARRIIVSAPNAKELVRQLEEYEPEFDEITSKLVWDEVDRISYVPGSEVATAT
What is the function of this protein?
Cytokinin-activating enzyme working in the direct activation pathway.  Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms.
What are the official names of this protein?
Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG7, Protein LONELY GUY 7.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: BGLG_ASPFN
Sequence: MASIAHLVVSGLLAATAVNGQNYGGSGRSDDAFSYVQPRNTTILGQYGHSPAVLPSPNATGAGGWEEALAKAQQFVAQLTLEEKADMVTGQPGPCVGNIVAIPRLGFKGLCLQDGPLAIRVADYASVFSAGVTAASTWDKDILYERGVAMGEEFKGKGAHVALGPVAGPLGRSGYGGRNWEGFAADPYLTGVAMERTIQGYQDAGVQACAKHFIGNEQETQRNPNYNPNGTLTDVIQEAISSNIDDRTIHELYLWPFANAARAKVASVMCSYQRLNGSYACQNSKVLNGLLKEELGFQGYVQSDWGGTHSGVSSIEGGLDMNMPGGLGQYGQTPEAGSFFGKNVTFAVNNGTVDISRVDDMIVRIMTPYYWLGQDQGYPEIDPSSADLNTFSPRSTWLREFNLTGERSRDVRGDHGELIRRHGAEATILLKNENKALPLKAPKSIAVFGNDAGDTTEGAVNKATFEFGTLAAGGGSGTGRFTYLVTPLEALKARGKQDNTLVQWWLNNTLIADSDVTSLWVPTPPDACLVFLKTWAEEGSDREYLSVDWNGNEVVDSVASKCNNTIVVTHSSGINELPFANHPNVTAIVAAHYPGQESGNSIVDILYGDVNPSGKLPYTIAKNGSDYNAPPTTAVETTGADDWQAWFDEKLEIDYRYFDAHNISVLYEFGFGLSYTTFSLSDIKTEPLAESISSVPEQLPIQPGGNPALWESVYNVSVTVTNTGDVKGATVPQLYVTFPDSAPAGTPPKQLRGFDKVSLAPGESQTVGFELMRRDLSYWDVVSQEWLIPEGEFTIRVGFSSRDLSQETKITPVTA
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase G, Beta-D-glucoside glucohydrolase G, Cellobiase G, Gentiobiase G.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: 5MP1_CHICK
Sequence: MNKNQKPVLTGQRFKTRKRDEKEKFEPTVFRDTIVQGLNEAGSDLEAIAKFLDSAGSRLDYRRYADTLFDILVAGSMLAPGGTRIDDNDKTKMTRHCVFFAEEDHDAIRNYAQVFNKLIRRYKYLEKAFEDEIKKLLLFLKAFSETEQTKLAMLSGILLANGTLPATILTSLFTDNIVKEGIAASFAVKLFKAWMAEKDANSVTSALRKANLDKRLLELFPANRQNVDHFAKYFTEAGLKELSDFLRVQQSLGTRKELQKELQERLSQECPIKEMVLYVKEEMKRNELPEPAVIGLLWTCVMNAVEWNKKEELVAEQALKHLKQYAPLLAVFSTQGQSELILLQKVQEYCYDNIHFMKAFQKIVVLFYKADVLSEEAILKWYKEAHVAKGKSVFLDQMKKFVEWLQNAEEEFRI
What is the function of this protein?
Translation initiation regulator which may repress non-AUG initiated translation and repeat-associated non-AUG (RAN) initiated translation by acting as a competitive inhibitor of eukaryotic translation initiation factor 5 (EIF5) function.
What are the official names of this protein?
eIF5-mimic protein 1, Basic leucine zipper and W2 domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the BZW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARMC9_MOUSE
Sequence: MGDILAHESELLGLVKEYLDFAEFEDTLKTFSKECKVKGKPLCKNVGGPLKKDSKSLVIQRDLVAAFDSGDQKAFFDLWEGHIPSSVRDTDSLAQKLEFYLHIHFAIYLLKYCRGRPDKQELDKRISYFKTYLETKGAALSQTTEFLPFYALPFVPNPMVHPSFKELFQDSWTPELKLKLEKFLALTFKANNTPKLLTIYKENGPNSKELLQQLHQQLVEAERRAMTYLKRYNKIQADYHNLIGVTAELVDSLEATVSGKMITPEYLQSVCVRLFSNQMRQSLAHSVDFTRPGTASTMLRASLAPEKLKDVPLLPSLDYEKLKKDLIWGSDRLKAFLLQALRWRLTTSHPGEQRETVLQAYISNDLLDCHSHNQRSVLQLLHSKSEAVRQYMARLINALASLAEGRLYLAQNTKVLRMLEGRLKEEDKDVITRENVLGALQKFSLRRPLQTAMIRDGLIFWLIDLLKDPDCLSDYTLEYSVALLMNLCLRSAGKNMCAKVAGLMLKVLSDLLGHENHEIQPYVNGALYSILSIPSIREEARAMGMEDILRCFIKEGNAEMIRQIEFIIKQLNSEDLLDGVLESDDDEDEDDEEDHDIMEADLDKDELIQPQLGELSGEKLLTTEYLGIMTNTGKARRKGPASVQWSGDEPLRRPVTPGGHRTGCPVLGDHLISPQNAQQARNGCLRAMPVAHPDDYKEGKPGVTGCGTSSSFMDHKPREWSPAGHQKSRLVPTAALGWPREMTQDPSSGHITREFVPAFTCKPQVPSTPETVEQNPLKAKALSLAPQFSSSGPQQASRPASTASSTRGLHSSQSIRK
What is the function of this protein?
Involved in ciliogenesis (By similarity).  It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length (By similarity).  Acts as a positive regulator of hedgehog (Hh) signaling (PubMed:29459677).  May participate in the trafficking and/or retention of GLI2 and GLI3 proteins at the ciliary tip (PubMed:29459677).
What are the official names of this protein?
LisH domain-containing protein ARMC9.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localized to the proximal region in cilia. Stimulation of Hh signaling leads to redistribution of ARMC9 toward the ciliary tip within 6 hours, follow by a gradual return to its original proximal location (PubMed:29459677). Localizes to the daughter centriole of the primary cilium in RPE1 cells (By similarity).
Protein: BIRC8_HUMAN
Sequence: MTGYEARLITFGTWMYSVNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYPGCKYLLEEKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRVFMS
What is the function of this protein?
Protects against apoptosis mediated by BAX.
What are the official names of this protein?
Baculoviral IAP repeat-containing protein 8, Inhibitor of apoptosis-like protein 2, IAP-like protein 2, ILP-2, Testis-specific inhibitor of apoptosis.
What is the protein family that this protein belongs to?
Belongs to the IAP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_PARP8
Sequence: MSVAEIKKSDVVAQFARGANDTGSPEVQVALLTTRINELTVHFKAHTKDHHSRRGLLRMVSRRRKLLDYLKGKDADRYRALIEKLGLRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: IHFB_PECAS
Sequence: MTKSELIERLAGQQSHIPAKVVEDAVKEMLEQMASTLAEGDRIEIRGFGSFSLHYRAPRVGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: VAV2_HUMAN
Sequence: MEQWRQCGRWLIDCKVLPPNHRVVWPSAVVFDLAQALRDGVLLCQLLHNLSPGSIDLKDINFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSIAQNKGIRPFPSEETTENDDDVYRSLEELADEHDLGEDIYDCVPCEDGGDDIYEDIIKVEVQQPMIRYMQKMGMTEDDKRNCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSFLRAIDVSVMVGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVVPMQRVLKYHLLLKELLSHSAERPERQQLKEALEAMQDLAMYINEVKRDKETLRKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDRYLFLFDKVVIVCKRKGYSYELKEIIELLFHKMTDDPMNNKDVKKSHGKMWSYGFYLIHLQGKQGFQFFCKTEDMKRKWMEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKACKMFLRGTFYQGYMCTKCGVGAHKECLEVIPPCKFTSPADLDASGAGPGPKMVAMQNYHGNPAPPGKPVLTFQTGDVLELLRGDPESPWWEGRLVQTRKSGYFPSSSVKPCPVDGRPPISRPPSREIDYTAYPWFAGNMERQQTDNLLKSHASGTYLIRERPAEAERFAISIKFNDEVKHIKVVEKDNWIHITEAKKFDSLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERSASRASSRSPASCASYNFSFLSPQGLSFASQGPSAPFWSVFTPRVIGTAVARYNFAARDMRELSLREGDVVRIYSRIGGDQGWWKGETNGRIGWFPSTYVEEEGIQ
What is the function of this protein?
Guanine nucleotide exchange factor for the Rho family of Ras-related GTPases.  Plays an important role in angiogenesis.  Its recruitment by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity).
What are the official names of this protein?
Guanine nucleotide exchange factor VAV2, VAV-2.
Protein: TSAD_XANC5
Sequence: MKVLGIESSCDETGVAVYDTALSGVPALRAHAVYSQIALHAEYGGVVPELASRDHVRKLLPLIRQTLGEAGLRIDELDGVAYTAGPGLVGALLVGAGVARSLAWALDVPAIGVHHMEGHLLAPLMEDDPPQAPFVALLVSGGHTQLVSVKALGSYEVLGETLDDAAGEAFDKTAKMMGLPYPGGPQLAALAETGTPGRYKFARPMTDRPGLDFSFSGLKTQVLLAWRSSDQSDTTRADIARGFEDAVVETLAIKCLRALDAAGCNTLVVAGGVGANKRLRARLQEAAQRRGGRVCFPRPALCTDNGAMIAFAGALRLQAGEHADAAVHVTPRWDMACLPPLAAARESGVGNRE
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_SHEPC
Sequence: MKQLRLEPVVQVRGEINIPGSKSISNRALLLATLAQGTTTLTNLLDSDDIRHMLASLKQLGVNYRLSQNNTVCELDGIGGVISSASAQELFLGNAGTAMRPLCAALTLGQGEFTLTGEPRMEERPIGDLVDALRQLGANIVYLKNDGFPPLTINATGLNGGDVEIAGDLSSQFLTALLMVAPLAKGSVNIHVKGELVSKPYIDITIALMAQFGVNVINHDYARFEIVAGQRYISPGKVLVEGDASSASYFLAAGAIKGGEVKVTGVGRLSIQGDVKFADVLEKMGADIEWGDDYIIARGSPLTAVDLDMNHIPDAAMTIATAALFAKGTTVIRNIYNWRIKETDRLAAMATELRKVGAEVEEGNDYIKITPPAVINTAEIDTYNDHRMAMCFSMLAFADCGITINDPDCTSKTFPDYFKQFASLQG
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.