PharMolix/UniProtQA huggingface dataset:
Protein: CH60_PSEF5
Sequence: MAAKEVKFGDSARKKMLTGVNVLADAVKATLGPKGRNVIIEKSFGAPTITKDGVSVAKEIELKDRFENMGAQLVKDVASRANDDAGDGTTTATVLAQSIVNEGLKAVAAGMNPMDLKRGIDKATIAIVKELKGLSKPCADSKAIAQVGTISANSDNSIGDIIAEAMEKVGKEGVITVEEGSGLENELSVVEGMQFDRGYLSPYFINKPDTMVAELDGPLILLVDKKISNIREMLPVLEAVAKAGRPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAVLTGGTVISEEIGLSLESTTLEHLGNAKRVILSKENTTIIDGAGVEADIQARVTQIRQQVADTSSDYDREKLQERLAKLSGGVAVIKVGAGSEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALIRALQGINDLKGDNADQDVGIAVLRRAIEAPLRQIVANSGDEPSVVVDKVKQGAGNFGYNAATSEYGDMIEMGILDPTKVTRSALQAASSIGGLILTTEAAVAEIVEDKPAAGGMPDMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AK1C3_PONAB
Sequence: MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEECKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTAEDMRAIDGLNRNLHYFNSDSLASHPNYPYSDEY
What is the function of this protein?
Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids.  Acts as a NAD(P)(H)-dependent 3-, 17- and 20-ketosteroid reductase on the steroid nucleus and side chain and regulates the metabolism of androgens, estrogens and progesterone.  Displays the ability to catalyze both oxidation and reduction in vitro, but most probably acts as a reductase in vivo since the oxidase activity measured in vitro is inhibited by physiological concentration of NADPH.  Acts preferentially as a 17-ketosteroid reductase and has the highest catalytic efficiency of the AKR1C enzyme for the reduction of delta4-androstenedione to form testosterone.  Reduces prostaglandin (PG) D2 to 11beta-prostaglandin F2, progesterone to 20alpha-hydroxyprogesterone and estrone to 17beta-estradiol.  Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol).  Also displays retinaldehyde reductase activity toward 9-cis-retinal.
What are the official names of this protein?
Aldo-keto reductase family 1 member C3, 17-beta-hydroxysteroid dehydrogenase type 5, 17-beta-HSD 5, 3-alpha-HSD type II, brain, 3-alpha-hydroxysteroid dehydrogenase type 2, 3-alpha-HSD type 2, Chlordecone reductase homolog HAKRb, Dihydrodiol dehydrogenase 3, DD-3, DD3, Dihydrodiol dehydrogenase type I, HA1753, Prostaglandin F synthase, PGFS, Testosterone 17-beta-dehydrogenase 5.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5476_BACC0
Sequence: MGNEFRVCDDCQATNVKTLIPKLKKVDSCATIEVGCQSYCGPGRKKSFAFVNNRPVAAPTEDELIVKIEAKLNK
What are the official names of this protein?
UPF0741 protein BCAH820_5476.
What is the protein family that this protein belongs to?
Belongs to the UPF0741 family.
Protein: HUPK_RHILV
Sequence: MTFLLGAGTIGIDVTVSRALACSVAVKANRPRGLTRMFVGRQPEEAPVLAGQVFSLCGFAQSVAARLAVLAAADLAMNDEERLGASAGLLAERIFETLRALILQWPTPLPERFAADAGRHLREALAASLAIISHAKAGRTSRPRLAAAAERLSAAATALGIPGRGDTPLPETACAAILRDVEDDHVFAGRRPDPLTISDDAEVVARLRDEAGYASLPHLSGRIAETGAYARSASAGLPEAPHLARRLRARIGDVRISLTQLTALARTGDFDCASLACSGPTPGAGGYGAVECARGRLYHQIEIGGDGRLAAYRILAPTEWNFHPAGPFVETLLSSPVGADEAAVRSISRLAVLFDPCVAFEINVREAADA
What are the official names of this protein?
Hydrogenase expression/formation protein HupK.
What is the protein family that this protein belongs to?
Belongs to the HupK family.
Protein: EFG_ANOFW
Sequence: MARQFSLENTRNIGIMAHIDAGKTTTTERILFYTGRVHKIGEVHEGAATMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGAVAVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKIGADFLYSVKTLHERLQANAHPVQLPIGAEDQFTGIIDLVEMCAYHYHDELGKNIERIEIPEDYRDMAEEYRGKLIEAVAELDEELMMKYLEGEEITKEELKAAIRKATVSVQFFPVFCGSAFKNKGVQLMLDGVVDYLPSPVDIPAIKGTVPDTEEETVREARDDAPFAALAFKIMTDPYVGKLTFFRVYSGTLNSGSYVLNSTKRKRERIGRILQMHANHREEIAQVYAGDIAAAVGLKDTTTGDTLCDDKDPVILESMQFPEPVIQIAIEPKSKADQDKMSTALQKLQEEDPTFRAWTDQETGQTIIAGMGELHLDIIVDRMRREFKVEANVGAPQVAYRETFRKSAQVEGKFVRQSGGRGQYGHVWIEFSPNEEGKGFEFENAIVGGVVPREYIPAIQAGLEDAMQNGVLAGYPVVDIKAKLFDGSYHDVDSSEMAFKIAASMALKNAAAKCDPVLLEPIMKVEVIVPEEYLGDIMGDITSRRGRVEGMEARGNAQVVRAMVPLSEMFGYATSLRSNTQGRGTFTMVFDHYEEVPKSIAEEIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C5I_ORNMO
Sequence: MLVLVTLIFSFSANIAYADSESDCTGSEPVDAFQAFSEGKEAYVLVRSTDPKARDCLKGEPAGEKQDNTLPVMMTFKNGTDWASTDWTFTLDGAKVTATLGNLTQNREVVYDSQSHHCHVDKVEKEVPDYEMWMLDAGGLEVEVECCRQKLEELASGRNQMYPHLKDC
What is the function of this protein?
Bifunctional protein derived from blood-feeding ticks that specifically prevents complement-mediated C5 activation and acts as a scavenger for inflammatory modulators such as leukotriene B4 (LTB4).  C5 and LTB4 binding activities are independent (PubMed:23625922).  Inhibits classical and alternative pathways of complement activation by preventing the cleavage of complement C5 by both classical and alternative C5 convertases (PubMed:15699138) (Probable).  Inhibits complement in all species tested (rabbit, rat, guinea pig, mouse, pig, and human) (PubMed:27018802).  Also binds fatty acids such as palmitoleic acid and ricinoleic acid, as well as inflammatory modulators LTB4 (and presumably arachidonic acid (AA)) that may be sequestered to interfere with the host inflammatory response (PubMed:23625922).  Does not bind to leukotriene C4 and thromboxane B2 (PubMed:23625922).  In vivo, when tested on the mouse model of immune complex-induced acute lung injury (IC-ALI), shows a potent inhibitory activity of the pathology, equally dependent on both C5 inhibition and LTB4 binding for full activity (PubMed:23625922).
What are the official names of this protein?
Complement inhibitor, CI, OmCI.
What is the protein family that this protein belongs to?
Belongs to the calycin family. Lipocalin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RNZ_BRASO
Sequence: MFELIFLGTSASVPSHDRNHPGLLVQAGGQRILVDCGEGIQRQLLASGAGFRRLDRILLTHGHLDHVLGIPGLFSTLRLRRSADVMSVHGSPGTIDVVIRMLAGLWGDGRAPIPLELVPLTPGQVLDAGAFTINCFAVRHRDTDSFGFEFVSPARRHLLPERLAALAVPDGPIRKTLADGYPVTLDDGRIVTPEDVLGTPGGGKKLVIVGDTETTDGLQAHVRGADLLVIEATFLQRDSATARDYGHLTAAEAAALAASGNVGQLVLNHISGRYPDEEILAEARSIFPATRIASDFDRLTV
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: YCF2_ACOCL
Sequence: MKRHQFRFWIFELREILREIKNSPHFLDSWTKFDSVRSLIHIFFHQERLMKLFDPRIWSILLSRDSQGSTSNRYFIIKGLVLLVVAVLISRINNRNMVERKNLYLRGLLPIPMNSIGPGNETLEESFWSSDINRLIVLLLYLPKGKKTSESCFMDPKESLWLFPINKINQKCIMPESNRGSRWWRNRIGKKRDSSCKISTKTVAGIEISSKEKDLKYLEFLFLSYTDDPIRKDRFFSKVQNVSSNIQYDSTRSIFVQVTDFSQSKGSSDQSRDHFDSISKEDSEYHTLIDQTEIPQLKGRSIPGDPSFLQTERTEIESDRFPKCLSGSSPMSPLFPEHEKQMIIHRLPEEIDEFLGNPTRSIRSFFSDRWSELHMGSNPTDRSTRDQKWLKKQQDVSFVSSRRSENKEMVDIFKIITYLQNTVSIHPISSDPGCDMVPKDEPDMDSSNKISFLNKNPFFDLFHLFHDRNKGGYTLHHDFESEERFQEMADLFTLSITEPDLVYHRGFAFSIDSCGLDQKKLVNGKEKTKDESKKKSLLVLPPLFYEENAFFYRSIRKKPVWIHCGNDLFASNNIMEAVNQYRLIRNLIQIQYSAYGYIRNVLNRFFLMNRSDRNFEYGIQRDQIGNDTLNHITIMKYTINQHLSNLKKSQKKWFDPLISRTERSMNRDPNAYRYKWSNGSKNFQEHLEHFVSEQKNRFQVVFDQLRINQYSINWSEAIDKQDLSKSLRFFLSKSLLFLSKPLRFFLSKSLPLFFVSIGNSPIHRSEIHIYELKGPNEPLCNQLLKSIGVQIIHLHKLKPDHDTSQRSKFLINGGTISPFLFNKIPKWMIDSFHTRKNRSKSFANTDSYFSMISHDRDNWLNPVKPFHRSSLISSFYKANQLRFLNNPHHFWFYCNKRFPFYVEKTRINNYDRTYGQFLNILFIRNKIFSLCVGKKKHLLPIYSQVSDIFIPNDFPQSGDETYNLYKSFRFPIRPDPFVRRALYSIADISGTPLTEEQIVNFERTYCQPLSDMNLSDSEGKNLHQYLSFNSNIGLIHTPCSEKNLPYVKRKKQSLYLRKKRSLYLKKCVEKGQMYRTSQQRDSAFSKWNLFQTYMPWFLTSTGCKYLTSVLLDIFSDRLSILSSSPKLVSILNSIMHRSDISRLIKKWWTILPQWNLISEISSKCLQNLLLSEEMIHRNNESPVSMILTHLRSTNAREFLYSILFLLLVAGYLVRTHLLFVSRVSNELQTELEKIKSLMIPSYMIELQKLLYRYPTSTSKSESESESEYEYELNSFLLNNLFALEQLDWNIDLISIISNTITFSRNTRHLSRTSKEIYSLIRERKNVNSDWIEDRVESWVTINDLIDEDERDLAVQFSTLTTEKRIDQILWSLTHSHPVSKNDLDYQIIEQPGLISLRYLVDIHKKDLMNYEFNGSCLAEKRIFLANYRTITYSQTPSRGKPFSLRLDLSPSRGILVIGSIGTGRSHLVKYLATNSYVPFITVFPDRGLSDRPIYCFMDEDTDPDEDYDYIDDDIDIDSDNFDTELETIADVVTMDNMLLKVIRFDILGQFELAKTMSPCIIWIPNIHDLYLNESNYLSLGLLTNFLSSLYGDCETTRNILVFASTHLPQLVDPVLIDPKKFNTCIKIRRLLSPQQRKHFFNLLYTRGFHSENKMFHANGFGSITMGSNARDLVALTNEVLSISITQKKSILETNTIRLALHRQTWDLRSHVRSVPDHGILFYQIGRAVAQNVLLSNCCTDPISIYMKKKSCNEGFSYLYKWYYELGTSMKKLTILLYLLSCSAGSVAQDLWSPPGPDENSWITSDRFVENDSDLVDSLLEIEGALVGSWLLRSEPRNPLDMMQKRSCSIFKKDESEFAEGEGALALDPQEMLFYNQIVWAPRLWRPPCGKLFDCIEYSQEDDDDWEFWQSGTKYYWMRDSEGGQGFWVSQLKKFLWNPEAADPFLFLFKDQPFVSDSDFSSYHQPFSNFLVELMPPFKASSVSLYKGWVNKKLQEMCLEYLSDRERWLRTNSSLSHGSFRSNTLSESYQYLANLFLSNATLLDQMTKTLLRKRWLFPDEMKDLIHGTGGGTELTGR
What is the function of this protein?
Probable ATPase of unknown function.  Its presence in a non-photosynthetic plant (Epifagus virginiana) and experiments in tobacco indicate that it has an essential function which is probably not related to photosynthesis.
What are the official names of this protein?
Protein Ycf2.
What is the protein family that this protein belongs to?
Belongs to the Ycf2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: PSB11_MOUSE
Sequence: MALQDVCKWQTPDTPRPSIHLPQAGGWAVPRGCDPQTFLQIHGPRLAHGTTTLAFRFRHGVIAAADTRSSCGSYVACPASRKVIPVHQRLLGTTSGTSADCATWYRVLRRELRLRELREGQLPSVAGTAKLLAAMMSCYRGLDLCVATALCGWDHSGPALFYVYSDGTCLQGDIFSVGSGSPYAYGVLDRGYHYDMTIQEAYTLARCAVAHATHRDAYSGGSVDLFHVRESGWEYVSRSDACVLYRELQKARSLEQELEAKACGIYPEPATPQGARECKELFVEQEEVTPEDCAIIMKTETM
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.  Incorporated instead of PSMB5 or PSMB8, this unit reduces the chymotrypsin-like activity of the proteasome.  Plays a pivotal role in development of CD8-positive T-cells.
What are the official names of this protein?
Proteasome subunit beta type-11, Proteasome subunit beta-5t.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PAND_AQUAE
Sequence: MLREMLKSKIHRLTVTDADLHYEGSLSLDEYLMELADLKPFEKIDVYNINNGARFQTYVIPAPRYSGEVKLNGAAARLGHKGDLIIIASYAQYTEEELENYAPKLIFVNEKNQPVEVKESTEVK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_DESVV
Sequence: MRFVDEATINVRAGKGGNGCLSFRREKFIPRGGPDGGNGGDGGSVILRPTNRLLSLYDFRLQRNYEARNGQSGMGSQCDGRKGEDLVLELPLGTLVFEVDDEGHEQMIADLSDPDGVFVVARGGRGGKGNEHFKSSTMRAPRFAQKGEPGEERRLRLELKILADAGLLGLPNAGKSTFISRISAARPKIAAYPFTTLTPNLGVMIDEVDPDRRMVIADIPGLIEGAHTGQGLGHRFLKHVERTRFLVHILSIEDIDPENPWTGFDLINEELARFDEVLREREQIEVVNKIDLRTPEEVDALRQQAAQQGRRIFFISAMHGEGIEEVVDAMWRLRDTIDMHEPLVHLQEVEEEDEEFEDIEVVYTRE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLR2_CANLF
Sequence: MSRVLWTLWVLGAVTNLSKEEAPDQSSSLSCDPTGVCDGRSRSLNSMPSGLTAAVRSLDLSNNEITYIGNSDLRDCVNLKALRLESNGINTIEEESFLSLWSLEHLDLSYNLLSNLSSSWFRPLSSLKFLNLLGNPYKSLGETPLFSQLTNLRILKVGNIYSFTEIQDKDFAGLTFLEELEIDASNLQRYEPKSLKSIQNISYLALRMKQPVLLVEIFVDLSSSLKHLELRDTHLDTFHFSEASINETHTLVKKWTFRNVKVTDRSFTGVVRLLNYVSGVLEVEFEDCTLYGLGDFDIPDVDKIKNIGQIETLTVRRLHIPHFYSFYDMSSIYSLTEDVKRITVENSKVFLVPCLLSQHLKSLEYLDLSENLMVEEYLKNSACEDAWPSLQTLVLRQNHLASLERTGETLLTLKNLTNIDISKNSFHSMPETCQWPEKMKYLNLSSTRIHSVTGCIPKTLEILDVSNNNLNLFSLNLPQLKELYISRNKLMTLPDASLLPMLLVLKISRNAITTFSKEQLDSFHTLKTLEAGGNNFICSCEFLSFTQEQQALAKVLIDWPANYLCDSPSHVRGQQVQDVRLSVSECHRTALVSGMCCALFLLILLTEVLCHRFHGLWYMRMMWAWLQAKRKPRKAPSRDVCYDAFVSYSEHDSYWVENLLVQKLEHFNPPFKLCLHKRDFIPGKWIIDNIIDSIEKSRKTIFVLSENFVKSEWCKYELDFSHFRLFDENSDAAILILLEPIEKKAIPQRFCKLRKIMNTKTYLEWPTDDAQQEGFWLNLRTAIKS
What is the function of this protein?
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components.  Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).  May also promote apoptosis in response to lipoproteins.  Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway.  Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides (By similarity).
What are the official names of this protein?
Toll-like receptor 2.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein. Membrane raft. Note=Does not reside in lipid rafts before stimulation but accumulates increasingly in the raft upon the presence of the microbial ligand. In response to diacylated lipoproteins, TLR2:TLR6 heterodimers are recruited in lipid rafts, this recruitment determine the intracellular targeting to the Golgi apparatus. Triacylated lipoproteins induce the same mechanism for TLR2:TLR1 heterodimers.
Protein: PYRG_CHLTE
Sequence: MARPKNVKHIFVTGGVISSLGKGILSASLGLLLKSRGLRVAIQKYDPYINVDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFLDEPTSQACNLTMGRVYKSVIDKERRGEYLGGTVQVVPHVIDEIKEKMGDLAKNGSIDVLITEIGGTIGDIESLPFLEAMRQLKLELGEHNLLNIHLTFVPYIKAASELKTKPTQHSVKMLLETGIQPDILVCRSEKPLSREIKNKVGHFCNVHDLDVIGLNDCDTIYEVPLMLLKEQLDLRVMKKLGLKKFREPNLEYWKNFCEKVKHPKDGEITIGICGKYTEYPDAYKSIIESFIHAGASNDVRVLVKMLRAEDAEDPKFDISSAFKGISGLLVAPGFGDRGIEGKVRFVQYARENNIPFFGICLGMQCATIEFARNICDLPDANSTEFNKRTRFPVIDLMEHQKKVKEKGGTMRLGSYPCILKEGSKAHELYGKFLINERHRHRYEFNNQFRKLFEEKGMIFSGTSPNGDLVEIVELKNHRWFVAVQFHPELKSRVQKVHPLFDGFVHAAKEFAQGKRQLSLEVEMPRLSSTEMENAG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ENO_STRPS
Sequence: MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDGVETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQEGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: GATB_PROM9
Sequence: MNNLESWEAVIGLETHVQLNTKSKIFTSASTAFGDAPNTHIDPVVCGLPGTLPVLNETVLEYAVKTSLALNLNVAEHCKFDRKQYFYPDLPKNYQISQFDEPLAENGWLEVEIIEKDKDPYTKKIGIERLHMEEDAGKLVHSGSDRLAGSKYSLVDYNRAGIALCEIVSKPDIRTGREAAEYASEIRRTVRYLGVSDGNMQEGSLRCDVNISVRKGPNAPFGTKVEIKNMNSFSAIQKACDYEIARQIEVYENGGEIFQETRLWDEAKQLTKSMRLKEGSSDYRYFPDPDLGPIEITKAQKEIWFNELPELPSKKRNKYVNEFGLSAYDARVISDEINMANFFEETVANGAEAKLASNWVTSDIVGYLKANKLSFSELKLSPENLAEMINMILKNTISGKIAKEILPELIKKNISPKKLVEEKGLAMISDSSSILPIINELINEYPNEVQAFRNGKTKLLGFFIGQLMKRTKGKADPKLANKLLAEKLNG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LCRV_YERPE
Sequence: MIRAYEQNPQHFIEDLEKVRVEQLTGHGSSVLEELVQLVKDKNIDISIKYDPRKDSEVFANRVITDDIELLKKILAYFLPEDAILKGGHYDNQLQNGIKRVKEFLESSPNTQWELRAFMAVMHFSLTADRIDDDILKVIVDSMNHHGDARSKLREELAELTAELKIYSVIQAEINKHLSSSGTINIHDKSINLMDKNLYGYTDEEIFKASAEYKILEKMPQTTIQVDGSEKKIVSIKDFLGSENKRTGALGNLKNSYSYNKDNNELSHFATTCSDKSRPLNDLVSQKTTQLSDITSRFNSAIEALNRFIQKYDSVMQRLLDDTSGK
What is the function of this protein?
Possibly involved in calcium regulation of YOP expression, which includes the export process.
What are the official names of this protein?
Virulence-associated V antigen, Low calcium response locus protein V.
What are the subcellular locations of this protein?
Secreted.
Protein: PADI3_MOUSE
Sequence: MSLQRIVRVSLEHPTSAVCVAGVETIVDIYGAVPEGTDMFEVYGTPGVDIYVSPSMERSRERADTRRWCFNKGLEIIVIMNSPSNDLNDSHVQIAYHSSREHLPLAYAVLYLTCVDITLDCDMNCADRQDRSFVDKRQWVWGPDGYGAILLVNCDRDNVDSNAQDNCDQYVRCLQDLEDMSVMVLRTQGPEALFEDHRLILHTSSCDAERARVFHVCGPEDSCESYKCVLGPDRMSYEVPRLKGYEERFFVEGLSFPDAGFPGLISFHVTLLDDSNEDFSETPIFTDTAVFRVAPWIMTPSTLPPLEVYVCRVRNNTCFVEAVEELARKAGCKLTICPQAENRNDRWIQDEMELGYVQAPHKTLPVVFDSPRNGELQGFPYKRILGLDFGYVTREPKDSSVSGLDSFGNLEVSPPVVANGKEYPLGRILIGGNLPGSRGRRVTQVVRNFLHAQKVQPLVELFVDWLAVGHVDEFLSFVPAPDGKGFRLLLASPGACFRLFQEKQKWGHGRSLLFEGVIGDRRVQTVSINQILNNQSLINFNKFAQSCIDWNREVLKRELGLAEGDIIDIPQLFKTEKRKAVAFFPDLVNMLVLGKHLGIPKPFGPIINGRCCLEEKVRSLLEPLGLHCTFIDDFTPYHMLHGEVHCGTNVRREPFAFKWWHMVP
What is the function of this protein?
Catalyzes the deimination of arginine residues of proteins.
What are the official names of this protein?
Protein-arginine deiminase type-3, Peptidylarginine deiminase III, Protein-arginine deiminase type III.
What is the protein family that this protein belongs to?
Belongs to the protein arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_RICTY
Sequence: MVVDADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESKVALKQITASIPTPQKICKILNDYVVGQDKAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLISAEFNIAKAQKGIIYIDEVDKIARKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNILFICGGAFMGIDRIIRSRTNHSSIGFAANINIDKEKNNNEVLKSLEIEDLTKFGLIPEFIGRLPIVTTLEELDKESLITILTKPKNAIVKQYQKQFELDDAELVIEYSALEAIAEKALVKKTGARGLRSILEHLLLDSMYKVAELKKQRVTLTKEVVDGLIEPVMTSIISTKLNKKQQMIEDIPA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: MUTX_STRMU
Sequence: MTKLATICYIDNGCELLLMHRNKKPNDVHEGKWISVGGKLEKGESPDECARREIFEETHLIVKQMDFKGIITFPDFTPGHDWYTYVFKVRDFEGRLISDKDSREGTLEWVPYNQVLTKPTWEGDYEIFKWILDDAPFFSAKFVYQEQKLVDKHVIFYEK
What is the function of this protein?
Involved in the DNA repair system to avoid A. T to G. C transversions.  Degrades 8-oxo-dGTP to the monophosphate, but is also active on all of the nucleoside triphosphates (By similarity).
What are the official names of this protein?
8-oxo-dGTP diphosphatase, 8-oxo-dGTPase, 7,8-dihydro-8-oxoguanine-triphosphatase, Mutator protein MutT, dGTP pyrophosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: RD2_PHYIT
Sequence: MRLSYVIVVIATSFLVTTEALSTNTGVQAANVVGPAQRLLRKHYTAAENDDDSEARALNTEKMKTMLKAGMTVDDYAAKLKLTDKIAAAANSARAMEKLGETLKMKKLLRYLNYVAEHTAV
What is the function of this protein?
Effector that enhances P. infestans colonization of Nicotiana benthamiana leaves (PubMed:24632534, PubMed:30329083).  Induces a weak Cell death response in N.  benthamiana.  PexRD2-induced cell death is dependent on SGT1, suggesting that PexRD2 is recognized by the plant immune system (PubMed:19794118).  Interacts with the kinase domain of the host MAPKKK epsilon, a positive regulator of cell death associated with plant immunity, and perturbs signaling pathways triggered by MAPKKK epsilon (PubMed:24632534, PubMed:28386988).
What are the official names of this protein?
RxLR effector protein PexRD2.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus.
Protein: HTPX_STRP4
Sequence: MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLVIALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFIIDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAVALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLVQLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKGGGFQKLFYTHPPISERIERLKHM
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.