PharMolix/UniProtQA huggingface dataset:
Protein: KA26U_MESMA
Sequence: MMSRLSVFILIALVLSVIIDVLNNSKVEGACVENCRKYCQDKGARNGKCINSNCHCYY
What is the function of this protein?
Recombinant toxin that reversibly blocks the voltage-gated potassium channels Shaker (IC(50)=0. 054 nM), rKv1. 2/KCNA2 (IC(50)=15. 6 nM), and rKv1. 3/KCNA3 (IC(50)=12. 5 uM).
What are the official names of this protein?
Mesomartoxin, MMTX.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family. Alpha-KTx 26 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YI95_SCHPO
Sequence: MKKEHASAFRQLWRAGMAAAISTRFPGHRFVIRDLLRNGFRQNNCSFYSKEKVENTVIFLEMAASRKSVEHLILKNRLHIQMFRRKAGQRLAHYSTAKERPYFLSAYDTYEWCLQRVGTIYNLYL
What are the official names of this protein?
UPF0593 mitochondrial protein C806.05.
What is the protein family that this protein belongs to?
Belongs to the UPF0593 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RSMH_HELPH
Sequence: MQEIESLHQSVLLQEVLQAFTPLEEGVLIDCTLGLGGHSKALLSQKPHLKLIGIDKDKFAQEIAKERLKAFEGRYNLLSGGFAKRFKEALETHNKEIKGVLVDLGVSSLQLDDDNRGFNFHSHTLDMRMDLKSDLNAQKVINSYPVVALEKIFRDYGEIKEYKKIAHKIAERRAKKPFKDAKDLSDFLSSLSKNKKIHPATLVFQAVRIEVNSELEELKEFLQCARNLKGAILCVISFHSLEDALVKNAFKDYAKNCICDPSSFQCTCSNNHALGAILTKKPITPSPEEIKNNRRSRSAKMRVFQFKP
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIC_BOVIN
Sequence: MGPGLRPLLPLVLCVGLSALVPSAGASGFRKRGPSVTAKVFFDVRIGDKDVGRIVIGLFGKVVPKTVENFVALATGEKGYGYKGSKFHRVIKDFMIQGGDFTRGDGTGGISIYGETFPDENFKLKHYGIGWVSMANAGPDTNGSQFFITLTKPTWLDGKHVVFGKVLDGMTVVHSIELQATDGHDRPFTDCSIVNSGKIDVKTPFVVEVSDW
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase C, PPIase C, Cyclophilin C, Rotamase C.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_YERPP
Sequence: MTDMYSLFVAFILGVVEGLTEFLPVSSTGHMIIVGELLGFTGDKAKTFEVIIQLGSILAVVVVFWRRLFGLIGIHFGAVPHEGKTNGHLTLGHILLAMIPAVILGLAFHDVIKALFDPKSVMYALVAGGVLLLAAEWLKPKNPKAVGLDDITYRQAFAIGCFQCLALWPGFSRSGATISGGMLVGVNRYAASEFSFILAVPMMIGASGLDLYKSLHFLTLGDLPMFAVGFITAFIVALIAIKTFLSLIKRISFVPFAIYRFIVAAVVYWVFM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRC_SYNFM
Sequence: MKKGKADPCNYLFRRARVIDPARDLDAVADVLVVDGILTDIKPNIDLPSDRLAHFAVIDASEKWIVPGLIDMHVHLREPGEEYKETIATGTMAAVAGGYTAVACMPNTKPVNDCAAVTEYILERAREQGHCRVLPVGAVSSGLEGRSLAEFGELKGSGAVAVTDDGRPVANSMLMRRALEYAKNFDLPVISHAEDPALSEGGLMNEGPTSTLLGLHGIPKAAEEVMVARDLALAELTGARLHIAHVSTAGAVRMIGEAKSRGVPVTAETAPHYFTLTDDRLMTFDTLYKVNPPIRGPADVEAIKRGLADGTIDAVATDHAPHSSIEKDTEFEYAANGIIGLESALPLILELVREKTLTPSQAVAKVSCNPARILGLPLGTLLLNQRACMTYLDPEFYFVLDCTTFRSKSRNCPFHGQPTRGRALMTFFNGKVAFSRLSK
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: TATD1_HUMAN
Sequence: MSRFKFIDIGINLTDPMFRGIYRGVQKHQDDLQDVIGRAVEIGVKKFMITGGNLQDSKDALHLAQTNGMFFSTVGCHPTRCGEFEKNNPDLYLKELLNLAENNKGKVVAIGECGLDFDRLQFCPKDTQLKYFEKQFELSEQTKLPMFLHCRNSHAEFLDIMKRNRDRCVGGVVHSFDGTKEAAAALIDLDLYIGFNGCSLKTEANLEVLKSIPSEKLMIETDAPWCGVKSTHAGSKYIRTAFPTKKKWESGHCLKDRNEPCHIIQILEIMSAVRDEDPLELANTLYNNTIKVFFPGI
What is the function of this protein?
Deoxyribonuclease which catalyzes (in vitro) the decatenation of kinetoplast DNA, which are circular DNA catenated to each other, producing linear DNA molecules (By similarity).  Plays an important role in chromosomal segregation and cell cycle progression during eye development probably via its DNA decatenation activity (By similarity).
What are the official names of this protein?
Deoxyribonuclease TATDN1, Hepatocarcinoma high expression protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: OR19A_DROME
Sequence: MDISKVDSTRALVNHWRIFRIMGIHPPGKRTFWGRHYTAYSMVWNVTFHICIWVSFSVNLLQSNSLETFCESLCVTMPHTLYMLKLINVRRMRGQMISSHWLLRLLDKRLGCDDERQIIMAGIERAEFIFRTIFRGLACTVVLGIIYISASSEPTLMYPTWIPWNWRDSTSAYLATAMLHTTALMANATLVLNLSSYPGTYLILVSVHTKALALRVSKLGYGAPLPAVRMQAILVGYIHDHQIILRLFKSLERSLSMTCFLQFFSTACAQCTICYFLLFGNVGIMRFMNMLFLLVILTTETLLLCYTAELPCKEGESLLTAVYSCNWLSQSVNFRRLLLLMLARCQIPMILVSGVIVPISMKTFTVMIKGAYTMLTLLNEIRKTSLE
What is the function of this protein?
Odorant receptor which mediates acceptance or avoidance behavior, depending on its substrates.  The odorant receptor repertoire encodes a large collection of odor stimuli that vary widely in identity, intensity, and duration.  May form a complex with Orco to form odorant-sensing units, providing sensitive and prolonged odorant signaling and calcium permeability.  Involved in the preference for citrus fruits for oviposition, especially through the response to valencene, the primary ligand of Or19a.  Larvae growing on citrus fruits suffer a reduced risk of parasitism since endoparasitoid wasps that parasitize larvae are strongly repelled by the smell of citrus, as well as by valencene.
What are the official names of this protein?
Odorant receptor 19a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Heteromeric odorant receptor channel (TC 1.A.69) family. Or2a subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KORC2_ECOLX
Sequence: MSDVNIRLECLRPAERWVQPTGAEIREVLHLAGLTGGQAARILGLGAKGDRTVRRWVGEDSPIPYAAWAILCDLAGIGAIWKGQG
What is the function of this protein?
Acts with KorA as corepressor in the control of the kilC and kilE operons.
What are the official names of this protein?
Transcriptional repressor protein KorC.
Protein: Y3070_LYSEN
Sequence: MTPTVPELEFAQATAFESNVPPLFPGRAGPDDGADRLRLRLAVRGWARPLDLIAASNSPDDVMAILGALAAEVETAVQTRPNQWYLSLAARKRELARRDDAQLRAAASASVPGDDDDPVLHAMRIALADAEPTLSALGTDVLAALGNACDWLGERWRHAVGAQRIAGELASRALDADLRRMTRDPMVGRSHRDTLARLIGFATAATQTPLSVAYVYGGGGAGKTTLLSFLQRDLSQRAEPVPVVRIDFDEPAIDPTRMVTLNIALVEQLARSVPAVCDRASDMLPALRDTALVQHDAGLSRGGPRKRIKSSRPESMLKAESVASQAASDEGSILYRLLAPDVVAGPILIVFDTAELVLAQSDHVASSLVSWLGFLHNEAGARDLRLVIAGRDPPDDPDLGHAANSLLSRLKDTGARIETPIGLPELDPAEAQQLLRNCGVDDPTAAAEAAAAVPGNPLLLRITADALLQGEAELRESVRRAHRDSRIDADSARNYLLRRVVAHVRDPIARPYVLAATYSPVVTAKLLEEVVIPAVDRSEREPGPGIPANKKAATAKAKRVFDALASTYWLTRQTLRSETVPFNREIRAFALKLLAATPEGALLERDVRQSAAIHHLRRRSADDRALALYHLAVLGHPYTVPRDLASVQTVLRDVIEELPADLRNRLAPPVGSVAPGVARGVARSSIDDMSDSDWQRYLEGDERSKRAGEGAQMVKADRAREALDLYLARPTRPPGLPPTFVIQAQADLGEWDEGIADIDAILEREADDWLARKSIGPEALSRIYWITRLALQAYGRLSTPHAMLLRNASETATGPGLSTLPALIAVAETMSGEPIMAGRMRSQALKTDAAGRTLLCPIHGHLPETIELFDAGIAVVQSDWRQRMIQLAPARLIRANEAHLRDLQSRLDALHAKPIAQVNQLFNKMRTGIAVEPTTMAGLNSAVLLLRGLTPEFYRPLREALLALCENGVASPMMRHAVDPLFERMSIRPAEMEPATFYRRLSNNPNAWCTAFIVYADRCRLLPGLCESLARYADSPKSRRIASSFLAWDKALCRGTSSDWGQPAKTRK
What is the function of this protein?
Involved in defense against bacteriophages.  When this probable 4 gene operon (bGSDM-FE772_23060-FE772_23065-FE772_23070) is inserted into E. coli it provides nearly 100-fold protection against phages T5 and T6 and about 8-fold against phage T4.  The operon without bGSDM no longer protects against phage (PubMed:35025633).  Probably a nucleotide hydrolase, possibly of ATP (Probable).
What are the official names of this protein?
Probable ATPase FE772_23070.
Protein: SMS1_MYOSC
Sequence: AGCKNFFWKTFTSC
What is the function of this protein?
Somatostatin inhibits the release of somatotropin.
What are the official names of this protein?
Somatostatin-1, Somatostatin I.
What is the protein family that this protein belongs to?
Belongs to the somatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHS1_TUBUN
Sequence: EMNFTRTMHGVMRNIAHFCSRSKSRVWGKDGWQKIVVCIVADGRKKVHPRVLDAFPAMGVYQAGIAKNSINGREVKAHVYEYTTQVSLDSDLKFKGAEKGIVPVQMIFCLKELNAKKLNSHRCIFQRFWSTLNPNVCILLDVGTRPGHDSLYHLWKAFDTDSNVGGACGEIKAMKGKGWMGLFNPLVAS
What is the function of this protein?
Polymerizes chitin, a structural polymer of the cell wall and septum, by transferring the sugar moiety of UDP-GlcNAc to the non-reducing end of the growing chitin polymer.
What are the official names of this protein?
Chitin synthase 1, Chitin-UDP acetyl-glucosaminyl transferase 1.
What is the protein family that this protein belongs to?
Belongs to the chitin synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FUCI_SHIDS
Sequence: MKKISLPKISIRPVIDGRRMGVRESLEEQTMNMAKATATLLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSIQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAVHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALTWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADISRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPLVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWKISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLAPMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
What is the function of this protein?
Converts the aldose L-fucose into the corresponding ketose L-fuculose.
What are the official names of this protein?
L-fucose isomerase, 6-deoxy-L-galactose isomerase, FucIase.
What is the protein family that this protein belongs to?
Belongs to the L-fucose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_LACJO
Sequence: MVDNSKIRVVVGMSGGVDSSVSALLLKQQGFDVVGVFMKNWDDTDDSGVCTATEDYEDVKKVADEIGIPYYSINFEKDYWERVFEYFLDEYKKGRTPNPDVMCNKEIKFKSFLDFAMDLDADYIAMGHYAATRVDDNGVVHMMRPKDGNKDQTYFLSQLSQDQLKKVIFPLANLTKPQVREIAIASGLATAKKKDSTGICFIGERNFKKFLSEFLPAQSGKMVTPDGKVVGEHAGLMYYTIGQRSGLGLGSTKESTDPWFVVGKDLKKNELIVEQGYDSKLLYATSLDASGVSFFTGQPDHDVDLKCTAKFRYRQPDVGVTMHYRAKDNTVHVEFDEPARAVTPGQAIVFYNGEECLGGATIDRAYQNEKQLQLV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRDB_THEP1
Sequence: MLELKPPLVLLSGPAGFGEYLKLMDHRYVGGVLLKTVTLHPKEGNPTPRMADSDFYVINRIGLENPGIHAFVENIPELPVPMIASLGGDSFEEYLEVARVFKKVADRFYAVEFNFSCPNVKEGGLSIVKNAEEWKKLLNTLRKELPDSFLIAKVGVEGIFVEDAAEFVMKTGWDGITLVNTVRGLHFEKDTMILGGLSGPVLKPIALRAVYEVKKRFPELFVIASGGVYSVKDAEEFLKVGADVIGVGSALFKDPGVVEEIGKYLLEVKR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with NAD(+) as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit, DHOD B, DHODase B, DHOdehase B, Dihydroorotate oxidase B, Orotate reductase (NADH).
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIG42_CRISI
Sequence: GFADLFGKAVDFIKS
What is the function of this protein?
Inhibits the formation of NO by neuronal nitric oxide synthase with an IC(50) of 26. 4 uM.
What are the official names of this protein?
Signiferin-4.2.
What are the subcellular locations of this protein?
Secreted.
Protein: RNM5_MYCMS
Sequence: MNKIKQIIIVEGKTDTDKLKSIYGNDLKTIQTKGLSLNKKTLEMIEEFNNKMGVIIFTDPDGAGKKIRQTIIDYLDNKVLNAFIKKDDINKTSKKIGIAEASDDAIKKALDNLIIYDKNNVSLSWTDYINNDFYLKSNRIVICKYFNFDNNISSKTLFKWLNWMNVSIDDIKKIIGE
What is the function of this protein?
Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor.  Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step.
What are the official names of this protein?
Ribonuclease M5, RNase M5, Ribosomal RNA terminal maturase M5.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease M5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_RIPO1
Sequence: MRSQWVAKRRGQSNVSQMHYARQGMITEEMDYVAKRENLPPDLIRQEVARGRMIIPANINHLNLEPMAIGIASKCKVNANIGASPNSSNLEEEVAKLNLAVKYGADTVMDLSTGGGDLDTIRTAIINASPVPIGTVPIYQAVESVHGNIEKLTPDDFLHIIEKHAQQGVDYMTIHAGLLIEYLPLVRSRLTGIVSRGGGIIAKWMLHHHKQNPLYTHFDEIIEIFKKYDVSFSLGDSLRPGCTHDASDEAQLSELKTLGQLTRRAWEHDVQVMVEGPGHVPMDQIEFNVKKQMEECSEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPDAEDVRNGLIAYKIAAHAADIARQRPGARDRDDELSKARYNFDWNRQFELSLDPDRAREYHDETLPADIYKTAEFCSMCGPKFCPMQTKVDADALTELEKFLAEQKNKEAIAH
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: CLP1_COCIM
Sequence: MSLPGLELSQQPIEARRAPPQPTQISLPKGSEWRFEVAFGNTTRVKLLAGTAELFGTELATSQTYTFSGTKAAIYTWHGCTLEVGAGDPVPIGPVGSAPVPPGPGNGGCQVEYIAEETPMAEYANVHFALETMRHDAKAAGRDGPRVLILGPEDAGKTSLAKILTGYATKMGRQPLVVNLDPSEGMLSVPGALTATAFRSMIDVEEGWGSSPMSGPSPIPVKLPLVYFYGLPACLDGDGSYYKAIVSRLALAVTGRMAEDSDAREAGVIIDTPGIIGQGKGASEDVIHHIVTEFSISTILVIGSERLYSTMVKNYDNKPIATSATAAASDERISVVKLTKSGGCVDRDATFMKYVRESQIRSYFFGSPVPSTASSALSLSSTTTGTTMTLSPHTSQVDFNSLSIYSITIATEGEEDEYDPSKFDSFLPGGHEENDHNTSLTGTTSLQPPSGLLPGLRSELPSATTGFPSASTSSTTPFTNLPSPAPMSLANTLLAITNAAPNASLDEVRDASIMGFIYIADVDEKKGQGGKLRLLAPVGGRVPNRAMIWGRKWPGEVVGLIG
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor CLP1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: DEOB_ENTFA
Sequence: MFKRVHLIVLDSVGIGEAPDAEKFGDVGSDTLGHIAKEAGLTIPHLEKLGLGTIAPLTGVKAVADHDGYATKLEEISVGKDTMTGHWEIMGLNIKKPFRVFPNGFPEELLKQIEDFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAAHEDIIPLEELYKICQYVRDITKDEPYMIGRIIARPYVGEPGNFTRTSNRHDYALDPFGHTVLDSLKENGNDVIAVGKINDIFNGQGITEAIRTKSNMDGVDQLLTVMNKEFTGLSFTNLVDFDALYGHRRDVKGYAKAIEDFDGRLPEIMAAMAEDDLLLITADHGNDPTFPGTDHTREYVPLLAYSKKMTKQGSLPQGFYSDISATIAENFEVPATENGQSFLNQLQ
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_SHESA
Sequence: MGINFDVSRPKARSSINMTTKFHTIGLIGKPHHPGTNQTLKRLHHWLTVQGYEVLVEERVASELGTNIIAVDLLEIGARCDLAIVVGGDGNMLGAARVLARFDVGVIGVNRGNLGFLTDLPPDAFEEALAKVLDGEFDTEHRFLLEAEVYRHGMLKASNTAVNEAVLHPGKIAHMIEFEVYIDNQFMYSQRADGMIVSTPTGSTAYALSAGGAILTPNLQALILVPMFPHTLSCRPIVVDACSTIKMVVSPENGENLEVSCDGHVHLAVLPGDEIIVRRSSEQLRLIHPKGHNYFHVLRSKLGWGSKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2B1_YEAST
Sequence: MSAKAEKKPASKAPAEKKPAAKKTSTSTDGKKRSKARKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.1, Suppressor of Ty protein 12.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: FBSB_SYNSC
Sequence: MDQTLIQEILEIVEQAAIASASLSGKGLKDEADALAVDAMRKRMNQIQMQGRIVIGEGERDEAPMLYIGEEVGTGTGPGVDFAVDPCEGTNLCAFNQRGSMAVLAASDRGGLFNAPDFYMKKLAAPPAAKGKVDIRKSATENIKILSECLGLPVDELNIVVMDRARHKDLIAEIRGTGARIQPISDGDVQAAIACGFAGTGTHCLMGIGAAPEGVISAAAMRALGGHFQGQLVYDPAIAQTSEWADMTKEGNLARLAEMGIADPDKVYEAEELACGEHVCFAGSGITDGLLFNGVKFEKDCTRTSSLVISNLDNTCRFTNTVHIKEDAQSIALS
What is the function of this protein?
Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively.
What are the official names of this protein?
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase, FBPase class 2/SBPase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 2 family.
Protein: LONM_CRYNB
Sequence: MLPLRAFARLAQRPRLSRPTQLARSSLPRPSPSRPAAHYLALAPAPSTRFLHSSPPVLKEKRWLNNTPPEDDGEDGQNPKQDDQVEKPLPDAESSKSAEERAKSQSSKPDIKASSSDSVSSSAPAPGSADGGSPPGAGGPKEVAKPVIPEIYPQVLAIPITHRPLFPGFYKAVTVRSPPVIKAIRELQAHGQPYVGAFLLKDSTVDSDVVTDINQVQPVGVFCQITSCFTSQEGEGKPEALTAVLFPHRRIKINELVKSSGTKGDGTVGVGGLVEGSQDSAKGEGEVKSFESEVPGVEEVREELGTVSIDSEQPDVHKENRDLETKEVTQIDFLHSLLPQVSLTNVSNLSTEPYEKDSQVIRAIMSELISVFKEIAQLQPMFREQVTSFAISNTSSQVFDEPDKLADLAAVVSTADVSDLQAVLSSTSIEDRLQRALVLLKKELINAQLQFKISRDVDTKIQKRQREYYLMEQLKGIKKELGMESDGKDKLVEGFKEKASKLAMPEGVRKVFDEELNKLVHLEPAASEFNVTRNYIDWLTQVPWGVHTPENYNISHAIKILDEDHYGLKDVKDRILEFMAIGKLRGSVEGKILCLVGPPGVGKTSIGKSIAKALGRQFFRFSVGGLTDVAEIKGHRRTYIGAMPGKPIQALKKVATENPLILIDEVDKISKAYNGDPASALLEMLDPEQNKSFLDHYLDVPIDLSKVLFVCTANVLETIPGPLLDRMEVLEVSGYVSAEKMNIAERYLSPQAKVAAGLEDVNIELEPGAIEALIRYYCRESGVRNLKKHIDKIYRKAAFKIVTDLGESGLPEPATPPAENQVEAQYPDIKPASELTSNVIPGTEVSGVDTKTDVTTVPREPMKVPAGIHVKVTQENLKDYVGPPLYHKDRLYTHSPPAGVSTGLGYLGNGSGAVMPVEINSMPGKGNLQLTGKLGEVIRESAQIAMSWVKSNAYLLGITKSEAEATLNDRDVHLHMPEGGIGKEGPSAGTAILTAFVSLFTKTRVDPDIAMTGEISLLGQVLPVGGLKEKILAAHRAGIKKLIVPAGCKPDIDENVPESVKGGIEFVFVEDVRQVLHEAFRGTEVEKRWQETLPMEEEPQRERH
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix.  May also have a chaperone function in the assembly of inner membrane protein complexes.  Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome.  Binds to mitochondrial DNA in a site-specific manner.
What are the official names of this protein?
Lon protease homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RUVB_MESH7
Sequence: MPENLEIRPSSFENFIGQKKLVETLQILISSSQKRKQSLDHILFYGPPGTGKTTLANIVANVLEAKIKYVQGPLLEKKSDVLAVLANISPDTIIFIDEIHGINKNIEELLYSAMEEFVIDLQIGVDGERKIMRMKLPQFTLIGASTKLAQISTPLQNRFGYVAKIVDYTLEDMIQIIRNSSAVLKLKMNTEIIKYIASFSNNTPRIANNLLKRIRDFALVLNAKRIDKDIVNKTFDSIGIYNQGLSQINIEYLNLLVKIFKGKSVALDVIANVLKEHRQTIINIIEPPLIEKELIEKTSRGRRITKKGRDYLLELKTN
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NDK1_SOYBN
Sequence: MDEQTFIMIKPDGVQRGLIGEIISRFEKKGFYLKGLKLVTVDRPFAEKHYADLSAKPFFSGLVDYIISGPVVAMIWEGKNVVTTGRKIIGATNPAQSEPGTIRGDFAIDIGRNVIHGSDAVESANKEIALWFPEGPANCQSSQHSWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase 1, Nucleoside diphosphate kinase I, NDK I, NDP kinase I, NDPK I.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
Protein: DAPF_SHEON
Sequence: MIQFTKMHGLGNDFMVVDGITQNVFFSPEQIRRLADRNFGVGFDQLLLVEPPYDPDLDFHYRIFNADGGEVENCGNGARCFARFVRNKGLTNKNKIRVSTSAGKMTLRLERDGTVTVNMGVPVLEPSQIPFKAKKAEKTYLLQTPQQTFLCGAASMGNPHCVLDVEDVANANVAEIGALLTKHERFPRGVNVGFMQVVNAGHIKLRVYERGAAETLACGTGACAAVVVGQIQGKLDQQVQVDLPGGSLTINWEGEGKPLWMTGPAQHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.