PharMolix/UniProtQA huggingface dataset:
Protein: UREE_STRT2
Sequence: MIFTKVDALVKDIDVDKYHIETVILSSDDLNKKIIRVKSDHGNEFGIRLDKGQKLQNGSAFFIDDHHVLAIGVESQDLIVISPKDMDEMGITAHILGNTHKPIEVKDAKIYLEVDPVVEQVLTQKEIAYTIEEVVLDKPLRHVNLTAHEH
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_FRACC
Sequence: MLDVNFFDELRIGLATADDIRQWSHGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMITKVDTDARHRDLPTLEARIGVEKQQLEDKKNADVEVRQKRLEADLAQLEAEGAKGDARRKVRESAEREMRQLRDRVQRKIDDLDRVFDRFKNMKVQDLEPDELLYRELRDRFGAYFDGGMGAEALQRRLADFDLAAEAESLRETIRSGKGQKKARALKRLKVVSAFLNTRNSPMGMVLDCVPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPEIIVNNEKRMLQEAVDALFDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKQMALELFKPFVMKRLVDLNHAQNIKSAKRMVERARPVVWDVLEEVITEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPSLDMVTGVFHLSRLAEGALGEGRSFSSVAEAQMAFDAREVALQAKIRVRLRDTTPPSDWVPPADWVTGDVFTLETTFGRCLLNEALPEGYPFINAQLNKKAQAAIVNDLAERYPKIQVAATLDALKSAGFYWATRSGVTVAIEDVVAPPNKAEILDDYEQRADRVQKQFDRGFLSDEERRSELVQIWTEATNKIAEAMEENFPETNPVYVLVNSGAAGNMMQIRQLAGMRGLVSNPKGEIIPRPIKANFREGLTVLEYFISTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREEDCGTERGILTRIARKGADGVLVRDRYAETSAYARTLASDAIDANGEVIVPAGTDAGDVAISQIIEAGIEQVRVRSALTCESRMGVCAQCYGRSLATGKLVDVGEAVGIVAAQSIGEPGTQLTMRTFHSGGVAGDDITQGLPRVVELFEARSPKGKAPITEVSGRVKIEETEKTFKVVVVPDDGSDEIAYPVSRRSRLRVREGDHIEVGSQIVDGAVDPHEVLRILGPRQVQLHLVDQVQEVYRSQGVSIHDKHIEIIIRQMLKRVNVLESGDTTLLPGELCERARFEAENRRVVETGGQPASARPVLMGITKASLATESWLSAASFQETTRVLTDAAINARSDSLVGLKENVIIGKLIPAGTGISRYRNIRVEPTEEARAAMYSVGAYEDGGVEYGAFGTGSGQAVPLDEFDYRSSGDFR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: GPPA_SALAR
Sequence: MLNSTSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLSSDNQLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTILGCPVQVISGEEEARLIYQGVAHTTGGAEQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLEHYFSDRNLAQENFDDAEKAARDVLRPVADKLRFHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFTELNIQFMTLAGGALREGLVYGMLHLTVDQDICSRTLRNIQRRFIIDTDQANRVAKLAGNFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITLQAQNENLTLTLPDGWLAHHPLGKELIDQESQWQSYVHWPLDIR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: FTSB_PASMU
Sequence: MRLFIFLLVAVLLLFQYDFWFGKNGYLDYKRTAQQIAQHKQENEKLSQRNQVVAAEIKDLKQGVEAIEERARFQHDMVKPDEIFYHIVKEQK
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: NB5R1_HUMAN
Sequence: MGIQTSPVLLASLGVGLVTLLGLAVGSYLVRRSRRPQVTLLDPNEKYLLRLLDKTTVSHNTKRFRFALPTAHHTLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDLVIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTGKGHFNIQPNKKSPPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCFLLFANQTEKDIILREDLEELQARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIREHLPAPGDDVLVLLCGPPPMVQLACHPNLDKLGYSQKMRFTY
What is the function of this protein?
NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.
What are the official names of this protein?
NADH-cytochrome b5 reductase 1, b5R.1, Humb5R2, NAD(P)H:quinone oxidoreductase type 3 polypeptide A2.
What is the protein family that this protein belongs to?
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PHL6_ARATH
Sequence: MYIKAIMNRHRLLSAATDECNKKLGQACSSSLSPVHNFLNVQPEHRKTPFIRSQSPDSPGQLWPKNSSQSTFSRSSTFCTNLYLSSSSTSETQKHLGNSLPFLPDPSSYTHSASGVESARSPSIFTEDLGNQCDGGNSGSLLKDFLNLSGDACSDGDFHDFGCSNDSYCLSDQMELQFLSDELELAITDRAETPRLDEIYETPLASNPVTRLSPSQSCVPGAMSVDVVSSHPSPGSAANQKSRMRWTPELHESFVKAVIKLEGPEKATPKAVKKLMNVEGLTIYHVKSHLQKYRLAKYMPEKKEEKRTDNSEEKKLALSKSEADEKKKGAIQLTEALRMQMEVQKQLHEQLEVQRVLQLRIEEHAKYLEKMLEEQRKTGRWISSSSQTVLSPSDDSIPDSQNMSKTKASSPQPPLPAENKASETEDDKCESPQKRRRLENIAESEDPKR
What are the official names of this protein?
Myb family transcription factor PHL6, Protein PHR1-LIKE 6.
What is the protein family that this protein belongs to?
Belongs to the MYB-CC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VP37D_HUMAN
Sequence: MYRARAARAGPEPGSPGRFGILSTGQLRDLLQDEPKLDRIVRLSRKFQGLQLEREACLASNYALAKENLALRPRLEMGRAALAIKYQELREVAENCADKLQRLEESMHRWSPHCALGWLQAELEEAEQEAEEQMEQLLLGEQSLEAFLPAFQRGRALAHLRRTQAEKLQELLRRRERSAQPAPTSAADPPKSFPAAAVLPTGAARGPPAVPRSLPPLDSRPVPPLKGSPGCPLGPAPLLSPRPSQPEPPHR
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.  May be involved in cell growth and differentiation.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 37D, ESCRT-I complex subunit VPS37D, Williams-Beuren syndrome chromosomal region 24 protein.
What is the protein family that this protein belongs to?
Belongs to the VPS37 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein.
Protein: MRAY_ALIB4
Sequence: MFYWLYRHLEINILQYISVRAGISFFIAFVLTMYLMPKFIRWARAKKASQPIYELAPENHKIKAGTPTMGGVVFIFSTIIATVLTAKLNNFYIVGGILTLALFSLIGIQDDYSKISKEKNSAGLTPRMKLIFQFLCAASIAGILFLYGHSTELFTPFYKFPLFEMGVFGIVFWMFVIVGSSNAVNLTDGLDGLATVPSILAFSTLSILVYVVGHAVFANYLLFPNIQIAGELAIMGSAICGALIAFLWFNSHPAEVFMGDSGSLPLGAFMGYLAIVAKSEILLLAIGFIFVWETVSVILQVGSYKLRQKRVFLMAPIHHHFEQKGWKENKIIVRFWIIAFMSNLIALLSLKIR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YOHK_SHIFL
Sequence: MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPFLMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVAMVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAVFGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLIAPFLFPIILAVMG
What are the official names of this protein?
Inner membrane protein YohK.
What is the protein family that this protein belongs to?
Belongs to the YohK (E.coli)/YwbG (IPA-22R) (B.subtilis) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSAJ_STIHE
Sequence: MKDFKIYLSTAPVVAFAWLTFTAGFIIEINRFFPDPLVFSF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SODF_METTM
Sequence: MEKKFYELPELPYPYDALEPYISEEQLRIHHEKHHQAYVDGANGVLRKLDDARENGEEVDIKAALKELSFHVGGYVLHLFFWGNMGPADECGGEPDGRLAEYIEKDFGSFQRFKKEFSQAAVSAEGSGWAVLTYCQRTDRLFIMQVEKHNVNVIPHFRILMVLDVWEHAYYIDYRNVRPDYVEAFWNIVNWKEVEKRFDDLF
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: TRME_SHEPU
Sequence: MKTLSERLNHALQLTGVTQSELARRIGIKQQSISQICSGKSARSRYTMQIAEALRVNAHWLATGDGEIGLGVGNVEVGPDIKGRIPLINWVQAGDWTEIAEGFAHEDAEEWREVTGKAHEGCFALRVKGDSMENPSGKKSIPEGAVIVVDPELPYSSGSLVVARLDDSKEATFKQLVIDGEQKYLKPLNPQYPAIPINGNCTIIGVVRQAIIDFW
What is the function of this protein?
May control the expression of the integrase and inhibit excision of the mobile element pMERPH, and regulate the expression of other genes as well.
What are the official names of this protein?
HTH-type transcriptional regulator for conjugative element pMERPH.
Protein: YQZL_BACSU
Sequence: MLNFTWNVFSQTGNVDTYLLFKELEKENMERPEELEDELARFDYPIL
What are the official names of this protein?
Uncharacterized protein YqzL.
Protein: Y562_SIRV1
Sequence: MPLPYKVNFKLPLEYLSLQDWNNFVQNLIFINQYGTAKLLQYYKNGSFQNLKDVFAKYLYVAQLKVNGYNVLHNLSEPLAYTFGNVFQELANKPSINLPEINVPVSSINYKLPPVEKQIEALIPNLISKISIPINIAGTQFTFSGNSNLAQLTSQYLQSVYLQTWRSITLQNLGNSSVQINNSIYLMPKQCLKITVSNPQEVQISAQSSTLLSELIEFNVIPITAYTITITNSQPDPTPSPFQQLLILNLSNIISSPSQLLNLQFCLDSQCKTPLYSWIESYNSNLSNVYIWINLPISIPANSSITIYMFVRNSIQYPYTGMRPDLTSTYAQYDNGKNVFLIYFNGNEPLSNFNTEGNTIQQISTIGPLGNTINAIYLSGYSNNVGFVYTGKSVPNQPVIVEASAKDMDNQTGGLGADNGQAGIADSTNTAIINAIGVTMGNNSDYFSQDFYINGSETRGYNLQGSAVSQWVYAWVVYQGSSASSWSGCIAPQLYSSNGGYCGTVNNNPLSSSTQLYLAVIGGVGYYDYWQTAWNFMRMRTYPPNGVMPSNTNPQLTTIYVA
What are the official names of this protein?
Uncharacterized protein 562.
Protein: OSTCN_CANLF
Sequence: YLDSGLGAPVPYPDPLEPKREVCELNPNCDELADHIGFQEAYQRFYGPV
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHS_PSEPK
Sequence: MNALNQAHCEACRADAPKVTDEELAELIREIPDWNIEVRDGHMELERVFLFKNFKHALAFTNAVGEIAEAEGHHPGLLTEWGKVTVTWWSHSIKGLHRNDFIMCARTDKVAETAEGRK
What is the function of this protein?
Involved in tetrahydrobiopterin biosynthesis.  Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2.  May also have a positive regulatory role in the expression of phhA (By similarity).
What are the official names of this protein?
Pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: MINE_METPP
Sequence: MSLLSFLLGEKKKTASVAKERLQIILAHERSGRGGSRPDYLEALQRELVAVISKYVSIKPEDIKVHLQKQDNLEVLEVKLELPEAARG
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: KADA_SULIN
Sequence: MKIGIVTGIPGVGKTTVLSFADKILTEKGIPHKIANYGDYMLNTALKEGYVNSRDEIRKLQIEKQRELQALAARRIVEDLSLLGDEGIGLIDTHAVIRTPAGYLPGLPRHVIEVLSPKVIFLLEADPRIILERQKRDNSRARADYSDTTVINEVIQFARYSAMASAVLVGASVKVVINQEGDPSIAASDIINSLM
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_CLOB8
Sequence: MSNKAVVVFSGGQDSTTCLFWALKEFDEVIAVTFDYNQKHRKEIECATSIAKELGIEHHILDMGLLNQLAPNALTRNDIEIKAGENGSLPSTFVEGRNMLFLTFAGVLAKVKGAKHIVTGVCETDFSGYPDCRDIFIKSLNVTLNLAMDYNFVVHTPLMWIDKAETWKMADDFGKLDYIREKTLTCYKGIVGDGCGECPACKLRKNGLDKYLESKKN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: AROM_ECOLI
Sequence: MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREEVMAEYAPEAGEDTILTLLNDNQLAHVSRRKVERDLQGVVEVLDNQGYDVILLMSTANISSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSLGNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIARLAAELLV
What is the function of this protein?
This protein of unknown function is encoded by a gene that cotranscribes with the aroL gene, which codes for shikimate kinase II.
What are the official names of this protein?
Protein AroM.
Protein: CBF1_YEAST
Sequence: MNSLANNNKLSTEDEEIHSARKRGYNEEQNYSEARKKQRDQGLLSQESNDGNIDSALLSEGATLKGTQSQYESGLTSNKDEKGSDDEDASVAEAAVAATVNYTDLIQGQEDSSDAHTSNQTNANGEHKDSLNGERAITPSNEGVKPNTSLEGMTSSPMESTQQSKNDMLIPLAEHDRGPEHQQDDEDNDDADIDLKKDISMQPGRRGRKPTTLATTDEWKKQRKDSHKEVERRRRENINTAINVLSDLLPVRESSKAAILACAAEYIQKLKETDEANIEKWTLQKLLSEQNASQLASANEKLQEELGNAYKEIEYMKRVLRKEGIEYEDMHTHKKQENERKSTRSDNPHEA
What is the function of this protein?
Required for chromosome stability and methionine prototrophy.  It is involved in chromosomal segregation.  Binds to a highly conserved DNA sequence (5'-RTCACRTG-3'), called CDEI, found in centromeres and in several promoters.  DNA-binding activity is enhanced by MET28.  Required as an auxiliary factor for transcriptional activation of sulfur metabolism together with MET4 and MET28.
What are the official names of this protein?
Centromere-binding protein 1, CBP-1, Centromere promoter factor 1, Centromere-binding factor 1.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion. Chromosome, centromere.
Protein: ECFA1_STAEQ
Sequence: MNGSNPIIEFKDVSFQYQSDAAFTLNRVSFSIPAGQWTSIVGHNGSGKSTIAKLMVGIEEPSEGQILFQNLPVDSQNKREVRKHIGIVFQNPDNQFVGSIVKFDVAFGLENQLVPYKEMVSKVNQVLTEVDMINKADDEPHSLSGGQKQRVAIAGVLALNPDVLILDEATTMLDPHGKSSLLNLVNEVKVNNHVTIISITHDLDEAMHADQIIVLNKGTVFKQGTPQDIFKCEEALISVGLDLPFPLKMNRLLGFDSTYVTYEGLIKKL
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LRWD1_XENTR
Sequence: MSKITADVLLKEGLPKSIHLKDLKKLNLSKMHLEMKDIDPKLFSQMVNLDELDISHNTLSELPDNLGLHNLRILNFADNHVEDVTVLKQFPNLEEVIYEDNIYLTVSDNYKVFCLLPKLRRLNNKDITSLANHVRFVNHRELSNRVEAHWDSKFKDNLPDKPSSQKINAVAKDFIKSVVNNIKYGPSSLKEFVRWKALGCSGKKRDSADDCTEGSPTKRTRIQHELQSIPLSPRKSNRLQNSPLSLTPIKRKQETSTQGTPSKSTETKSPKVALKSTPSKKQSNESSAKINGKQKLSLTPKIIQKALDNIEPLHFLQCHSKNNSCEDFKTQLWACAFEPILDSSSPKAVATCGGDSVCIIDCETGKVMKKYKVTGEEFFTLVWTTLTMIGKDEQKRKINVLAAGGKHGVVRIIHAKVSLCYGEIKAHKKAISIMCFSPKQDTFLFTGSYDKRIILWDIGVPDCDYNFRPSQLLTLDTTSVPLRMCLVPSCPDEFLVAACEDGCFAWDIRLDKKQGRRSYEVELNFPIYKEERKDNDFHVIDSLAFLNEDIIASKSVMQGSIYLWSWEKTLKTRKTKNVKKLDAVILAQMKWSSSETPYLVLSTSPERYCVFCGDEDGKIWIYDLDSCKADLQRGKLCSVVKEPTKILSWPILFSPKEKVEKTLINVVTVDPTMEYLVALTDINIVSIWKIK
What is the function of this protein?
Required for G1/S transition.  Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells.  Binds a combination of DNA and histone methylation repressive marks on heterochromatin.  Required for silencing of major satellite repeats.  May be important ORC2, ORC3 and ORC4 stability (By similarity).
What are the official names of this protein?
Leucine-rich repeat and WD repeat-containing protein 1, ORC-associated protein, ORCA, Origin recognition complex-associated protein.
What is the protein family that this protein belongs to?
Belongs to the LRWD1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, telomere. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore.
Protein: RL6_STRMK
Sequence: MSRVAKKPIDLGKVELNVQSDSVTAKGPKGTLSLAKPAGIAINVDNGVATLSTENADLVALTGTVRAILSNMVKGVSEGFERKLELVGVGYRAAMQGKDLSLSLGFSHPVVFVAPEGITLSTPTQTEILVQGADKQVVGEVAAKIRAFRKPEPYKGKGVKYSDEVIIRKEAKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LTHAD_YEAST
Sequence: MIVPTYGDVLDASNRIKEYVNKTPVLTSRMLNDRLGAQIYFKGENFQRVGAFKFRGAMNAVSKLSDEKRSKGVIAFSSGNHAQAIALSAKLLNVPATIVMPEDAPALKVAATAGYGAHIIRYNRYTEDREQIGRQLAAEHGFALIPPYDHPDVIAGQGTSAKELLEEVGQLDALFVPLGGGGLLSGSALAARSLSPGCKIFGVEPEAGNDGQQSFRSGSIVHINTPKTIADGAQTQHLGEYTFAIIRENVDDILTVSDQELVKCMHFLAERMKVVVEPTACLGFAGALLKKEELVGKKVGIILSGGNVDMKRYATLISGKEDGPTI
What is the function of this protein?
Catalyzes the deamination of L-threo-3-hydroxyaspartate to oxaloacetate and ammonia.  Shows a high specificity towards L-threo-3-hydroxyaspartate as other 3-hydroxyaminoacids, i. e.  D,L-erythro- and D-threo-3-hydroxyaspartate, D-threonine, L-threonine, D,L-allothreonine, D-serine, and L-serine, are not substrates for this enzyme.  Exhibits no detectable serine racemase activity.  Is responsible for the 3-hydroxyaspartate resistance of S. cerevisiae, and thus may be involved in the detoxification of naturally occurring 3-hydroxyaspartate.
What are the official names of this protein?
L-threo-3-hydroxyaspartate ammonia-lyase, L-threo-3-hydroxyaspartate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
Protein: Y3030_LEGPA
Sequence: MKFKKIILALACLSSPLYADQDQQLKSEIQRLQHQAEDLQAQLNRLQKQLANHKSSQQKHEQQAAAKPAEPKSKPTTKSGAAIEEKYHSSKVEVHAPDAHPESISFYPTALIADNRVVTYIAGTPVVSSPFLGDRPAFDGSDYIVNISSINRDVRLMQQRRRLYRAYQKIGYPIPNMPIISLSGKTEPAATFNNPFRSTNTDGDITLGSSELDIAAALNENVEAYIAIAYDESPPAIGPRVNNSAFNLNMGFVNIGNLDKSPLYFTAGQVYVPFGRYSSAMVSAPVTMNLARTKTRPVIFGYKSQADTGPFAAFYGYRSDTTLGRSGVGGVNLGYIFGFDNDINGEIGGGFITSVADAGGMQSTGSNVGTTFGGFGSITNGNENVRKTKAADVHGHVGYDRYNLTLEWVGAVQSFRPQDLSFNGQGARPQAAQAELGMTFMAFNRPASIGVGYQWTKEALALNLPKQRYIGVFNISIWKDTVESIEYRHDIDYGLTQFANGAAPPGLVNLPTLGTGKSADTVSAQIGVFF
What are the official names of this protein?
UPF0422 protein lpp3030.
What is the protein family that this protein belongs to?
Belongs to the UPF0422 family.
Protein: ACUK_BOTFB
Sequence: MSGETEIDDPEVSDGASENDYSDHEQELDVIGKEGDNQEMAEQKVRPDGEENGNTVGATATVTKPKFDPKDPLRPRRKKARRACFACQRAHLTCGDERPCQRCIKRGLADACQDGVRKKAKYLHDAPPEALRPVLGPTYNQQVSSNRATAASTPTEPSPGMGNFFSQPDTSPSYPLFGANQQGQMPPPLQNRLSFGSNQPSPISPTFHTAGNRPAGMQGISLPQVSNDSHSAFGGGAFFDPSNPALFNFDLEGLNFGNHYGALEFGMLGHMASGSAETPPQDSSAGMPQNVGDLGFSNNSAFTNNPPFNQIYSHDSLPDFAVGLDRPNGGNVFGNNNPHHGLPHAYAIATSGSQHSPSTDASPAASTMGFESSPTTTNYPAPASHRPAKRQDTKSGPSGKLGPSGILGKRNRDPSSIYDTVHEPYSYTTGFHSLTAFIQKRFSPNKTLRIAKSLASIRPSFISCTKTLNRQDLIFMEKCFQRTLFEYEDFMLNCCTPTVVCRRTGEIAAANKEFTLLTGWRKEVLLGNEANLNTNTGSGGPPSSGSSGRGSFTTPRMRPVNLADSNPNGKTQPIFLAELLDDDSVIEFYEDFARLAFGDSRGSVTTRYKLLRYQTAKDTSQSPEGDKGKRKDIVGFNGAGIGGMGNRIKEIDANNGIESLQQDGKVDCSSCWTIKRDVFDIPMLIVMNFLPCI
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis BC1G_14637.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SEM3C_BOVIN
Sequence: MAFQAVCILVGVFVCSTYVKGSPQPQARVYLTFDELRETKTSEYFSLSQYPLDYRILLMDEDQDRMYVGSKDHILSLNINNISQEPLSVFWPASAIKVEECKMAGKDPTHGCGNFVRVIQAFNRTHLYVCGSGAFSPVCAYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNSRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLEMDNPRTTLVYGIFTTSSSVFKGSAVCVYHFSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPVHRRPLIVRIGTDYKYTKIAVDRVNAADGTYNVLFLGTDRGTVQKVVVLPTNSSARSELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGLAQVSLHRCHIYGSACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQDSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGEESQKMRGDYGKLKALINSRKSRNRRNQLPES
What is the function of this protein?
Binds to plexin family members and plays an important role in the regulation of developmental processes.  Required for normal cardiovascular development during embryogenesis.  Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).
What are the official names of this protein?
Semaphorin-3C.
What is the protein family that this protein belongs to?
Belongs to the semaphorin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMG_HAEIE
Sequence: MKAKLVSLLAQANIKISDQQIQQLIDLVNLLNKWNKAYNLTSVRDPQEMLVKHILDSLVVSPYLQGDRFIDVGTGPGLPGLPLAIINPSKQFVLLDSLGKRISFIRNAIRELRLTNATPVLSRVEEYQPEDKFDGVLSRAFASLKDMTDWCYHLPKENGYFYALKGIYQEDEINELNKKYTIQKVIELSVPELIGERHLIVLR
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIRA_BACSH
Sequence: MRSTLRKDLIELFSQAGSEFISGQKISDALGCSRTAVWKHIEELRKEGYEVEAVRRKGYRLIKKPGKLSESEIRFGLKTEVMGQHLIYQDVISSTQKTAHELANNNAPEGTLVVADKQTAGRGRMSRVWHSQEGNGIWMSLILRPDIPLQKTPQLTLLAAVAVVQGIEAAAGIQTDIKWPNDILINGKKTVGILTEMQAEEDRVRSVIIGIGINVNQQSDDFPDELKDIATSLSQASGEKIDRAGVIQHILLCFEKRYRDYMTHGFTPIKLLWESYALGIGTNMRARTLNGTFYGKALGIDDEGVLLLETQEGIKKIYSADIELG
What is the function of this protein?
Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.
What are the official names of this protein?
Bifunctional ligase/repressor BirA, Biotin--[acetyl-CoA-carboxylase] ligase, Biotin--protein ligase, Biotin-[acetyl-CoA carboxylase] synthetase.
What is the protein family that this protein belongs to?
Belongs to the biotin--protein ligase family.