PharMolix/UniProtQA huggingface dataset:
Protein: WECF_ESCF3
Sequence: MTVLIHVLGSDIPHHNQTVLRFFNDVLAATSENAREFMVVGKDDGLIDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPKLWLALLSGGIKPSQFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHVAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLALFSEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LEU1_SALCH
Sequence: MSQQVIIFDTTLRDGEQALQASLSAKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARTIKNSRVCALARCVEKDIDVAAQALKVADAFRIHTFIATSPMHIATKLRSTLDEVIERAVYMIKRARNYTDDVEFSCEDAGRTPVDDLARVVEAAINAGARTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGIAVGNSLAAVHAGARQVEGAMNGIGERAGNCALEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMEEMGYKDTDYNMDHLYDAFLKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASVKLACGEEIKAEAANGNGPVDAIYQAINRITGYDVELVKYDLNAKGQGKDALGQVDIVVNHHGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: Y161_RICPR
Sequence: MLSLIGFIITISILVFIHEFGHYCIARYLDVKVEEFSIGFGKELIGITDRKGVRWKLCFIPLGGYVKIYGYDSSTRIIDKTKEVNEEVTFYSRSCLARFSIVAAGPLINYLLAVIIFTSFYCYFGKVEIPPIIGDVVAASPAERAGLKEGDKIVKVNNKYVKDFVDVQKEILINGFSSSTLTIARKSEEFKVNIRPQEIIISHPEKKKIGKTFRIGIIAKNEPIHTKIGIFGGVLEAINTTIDISTLTLKAISQMILGTRPLDEIGGPISIAQESGKSMASGAQMYLLFIAMLSINLGLLNLLPIPVLDGGHLIFILYEAITGRLPNPKTRNILLQLGAVIILLLIIISISNDIKNLFY
What are the official names of this protein?
Putative zinc metalloprotease RP161.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RECR_CHLCH
Sequence: MRFPSVALDTLIDEFAKLPGIGRKTAQRLAMYILHEPKIEAEQLAKALLDVKEKVVRCTICQNITDVGTDPCAICASKARDRTVICVVESPVDMLAFEKTGHYKGLYHVLHGVISPLDGVGPDDIKVRELLARIPVGEASGVREVVLALNPTIEGETTSLYLARLLKPLGIAVTKIARGIPVGAELEYVDEATLSRAMEGRTVV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: PDXH_SHELP
Sequence: MSNLSDIRREYTLGGLHREELPDNPMVLFEKWIEQIRDSEILPDPTAMSVATVDAEGQPFQRIVLLKRFDDNGFVFFTNLASRKAEQIAHNNKVSLLFPWHALERQVAVTGVAEQLSTTEVLKYFVTRPKESQIAAWVSKQSSKISARQALESKFAEMKAKFSQGEVPLPKFWGGYRVRPSSIEFWQGGEYRLHDRFLYSRKDSSLKEGGWDIDRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ARAQ_HALH5
Sequence: MKRKTSPILSWLLTIGFAFIAFIAVFPLLNLILASFRPSTELMRNGITLIFDPSTLTLDNFIYIFTEAGLYWTWFGNSVWISIVIVVLSLLFSSMVGYALAVYDFKGRNFFFLLVLIILMIPFEILMLPLFQLMIKLQLVNTYTAVILPAIVAPIAVFFFRQYALGLPKELMDAARIDGCTEYGIFFKIMLPLMGPSLAAMAILQGLNSWNNFLWPLVVLRSNDMFTLPIGLATLLTPYGNNYDILLAGSVMTIVPIVILFIFFQRYFIAGLTVGGVKG
What is the function of this protein?
Part of the ABC transporter complex AraNPQ involved in the uptake of arabinooligosaccharides (By similarity).  Responsible for the translocation of the substrate across the membrane (By similarity).
What are the official names of this protein?
Arabinooligosaccharides transport system permease protein AraQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
Protein: TUSA_SHIB3
Sequence: MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG
What is the function of this protein?
Sulfur carrier protein involved in sulfur trafficking in the cell.  Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA.  Interacts with IscS and stimulates its cysteine desulfurase activity.  Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation.  Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
What are the official names of this protein?
Sulfur carrier protein TusA, Sulfur mediator TusA, Sulfur transfer protein TusA, tRNA 2-thiouridine synthesizing protein A.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_CYAM1
Sequence: MAKVVGIDLGTTNSVIAVMEGGQPTVVPNSEGFRTTPSVVAYTKNGDLLVGQIAKRQAVINPGNTFYSVKRFIGRKFSEIEQEAKQVPYPVQADGKGNVRIFCSAKDKFFAPEEISAQVLRKLVDSASQYLGEKVTQAVITVPAYFNDSQRQATKDAGKIAGLDVLRIINEPTAASLAYGLDKKSNEKILVFDLGGGTFDVSILEIGDGVFEVLATSGDTHLGGDDFDKKIVDWLIDNWKRIEGIDLSKDKQALQRLTEAAEKAKIELSNVTQTDINLPFITATADGPKHLDQTLTRAQFEQLTSDLIERCRKPVEQALTDAKLSKQDIDEVVLVGGSTRIPAVQQLVKDLLGKQPNQSVNPDEVVAIGAAIQAGVLAGEVKNILLLDVCPLSLGVETLGGIMTKMIPRNTTIPTRKTEIYSTAVDNQTNVEIHVLQGERELAKDNKSLGTFRLDGIPPAPRGVPQIEVTFDIDANGILSVTAKERSTGKQQSITITGASTLDQSEIERMVKEAEKNAEEDRKKREQIETKNLAESVYYQAEKMGLKDNAQELKNAIDQLDYEGMKNLTQQVQTLIAQKASETSNAKTNGKASEKEDVIDADFKAQE
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CASP3_FELCA
Sequence: MENSENSVDAKSIKNSETKIFHGSKSMDSGIYMDNSYKMDYPEMGLCIIINNKNFHESTGMPSRSGTDVDAANLRETFTNLKYEVRNKNDLTREQIVALLDSVSREDHSKRSSFICVLLSHGEEGIIYGTNGPVDLKKLTGFFRGDYCRSLTGKPKLFIIQACRGTELDCGIETDSGTEDDIACQKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCSMLRLYAHELEFMHILTRVNRKVATEFESFSLDSAFHGKKQIPCIVSMLTKELYFYH
What is the function of this protein?
Involved in the activation cascade of caspases responsible for apoptosis execution.  At the onset of apoptosis, it proteolytically cleaves poly(ADP-ribose) polymerase PARP1 at a '216-Asp-|-Gly-217' bond.  Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain.  Cleaves and activates caspase-6, -7 and -9.  Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity).  Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes (By similarity).  Cleaves and inhibits serine/threonine-protein kinase AKT1 in response to oxidative stress.  Acts as an inhibitor of type I interferon production during virus-induced apoptosis by mediating cleavage of antiviral proteins CGAS, IRF3 and MAVS, thereby preventing cytokine overproduction.  Also involved in pyroptosis by mediating cleavage and activation of gasdermin-E (GSDME) (By similarity).  Cleaves XRCC4 and phospholipid scramblase proteins XKR4, XKR8 and XKR9, leading to promote phosphatidylserine exposure on apoptotic cell surface (By similarity).
What are the official names of this protein?
Caspase-3, CASP-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_SALEP
Sequence: MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLTSLGATIFFNHRPENVRDASVVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAGVHARLGHSRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYHGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQGMPDLHVTLNAPGRHNALNAAAAVAVATEEGIDDDAILRALESFQGTGRRFDFLGEFPLEPVNGKAGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRYTRTRDLYDDFANVLTQVDALLMLDVYPAGEAPIPGADSRSLCRTIRNRGKIDPILVSDPAQVATMLAPVLTGNDLILVQGAGNVGKIARYLSEIKLKPQIQEEEQHG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_ACIB5
Sequence: MSIIQEFKEFAIKGNMMDLAIGVIIGGAFGKIVDSLVKDIIMPLITVITGGGVDFSQKFIVLGANPNNLQSLDALQKAGINVLTYGNFLTILINFLILAWVVFLMVKLLNKLRRDKNEPEAPAATPEDIQLLREIRDELKKQA
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GTAA_DICDI
Sequence: MMGEFHTQFQQIKQNNINNNNNNNNNNSNNNNNFDPITSLTNNNNNKIISPLNSNRQQPNSNTNNNSNNKNNNKSNLLDIILDNNNLENNIDNNNNNNNNNNNNNNNNNNNNSKSIINLIDNNNNNNKNNNNNNNNNNILKIPIDYTPVDKNTESIFKGFSPFSFKQQQPIDTSDQQQKETKKLQLNINSNNKNNNNIINNSNNNNNINNIESNNNNLNSASTSPIPTPTSLTAVSVPSSSPLPSPTSPNTILQSPTTTTTTTTTTSNSSVSPQPTQINKTDKYLLPMSAPRSCEFCGSSQTPTWRRGPSGKGSLCNACGIKWRLKGKDGIFKPSQKQQNRQKPIMSAQKQPKQQQNQPQQQQPQQPQQPQQPQQQNQQQNQQQSIQSQPQQRQNNHLILNQQTINQHLQMLSKQHQQQASQSMFQQQQLHNNQHSNDSNYNSYNNNNNNNNNNYSQHEQLPPISSYNSMNNNNNSNNSNNNNNNNNYSQIPQYGSDDNVSVPNQSPDSYKPSKKRKPEFIHTDTSGNPIEFEKGYYCKYCKKTWPQSSFRNSQQFGAHCSNCSRKPKGELEELISIKKKLSKKKSKEGNYYQEEDGAVPYWDMNRYNNNNNNNNGINNNNNNNNNNNNNNSNNNGSYNNNNSNNNNNNNRIEPIVNNNINNFNSINNNNSNNNNNNNSTSQNAPLLQRLIHVVENQLLEPNELSSIREDIDIMKNDLILRKKKRIAQLNDLKQKANNDVQILKANIEKGSNQRSNESKSFITDLKQEIDKRLNQYTHIYIPPDHHLVPSSTNYLSIDSLQNSSSSNNYGTIHNSNNNNNNNNNNNKRSLVNLSPELIHSPLKKPMVGGYRDEQGMKHFSIDGDNLSLPSIS
What is the function of this protein?
Probable transcription factor.  Seems to act on the expression of the genes culC, culD, rnpA and sigB.
What are the official names of this protein?
Transcription factor stalky, GATA zinc finger domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: AMYB_DROME
Sequence: MFLAKSIVCLALLAVANAQFDTNYASGRSGMVHLFEWKWDDIAAECENFLGPNGYAGVQVSPVNENAVKDSRPWWERYQPISYKLETRSGNEEQFASMVKRCNAVGVRTYVDVVFNHMAADGGTYGTGGSTASPSSKSYPGVPYSSLDFNPTCAISNYNDANEVRNCELVGLRDLNQGNSYVQDKVVEFLDHLIDLGVAGFRVDAAKHMWPADLAVIYGRLKNLNTDHGFASGSKAYIVQEVIDMGGEAISKSEYTGLGAITEFRHSDSIGKVFRGKDQLQYLTNWGTAWGFAASDRSLVFVDNHDNQRGHGAGGADVLTYKVPKQYKMASAFMLAHPFGTPRVMSSFSFTDTDQGPPTTDGHNIASPIFNSDNSCSGGWVCEHRWRQIYNMVAFRNTVGSDEIQNWWDNGSNQISFSRGSRGFVAFNNDNYDLNSSLQTGLPAGTYCDVISGSKSGSSCTGKTVTVGSDGRASIYIGSSEDDGVLAIHVNAKL
What are the official names of this protein?
Alpha-amylase B, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: SENEG_KASSE
Sequence: MLSLKKSMLLLFFLGMVSFSLANKRSDGKRADEEGEDKRADEEGEDKRADEEGEDKRKRFLPFLIPALTSLISSLG
What is the function of this protein?
Antimicrobial peptide with activity against the Gram-positive bacterium S. aureus NCTC 10788 (MIC=50 um) and the yeast C. albicans NCPF 1467 (MIC=150 uM).  Ineffective against the Gram-negative bacterium E. coli NCTC 10418.  Induces a dose-dependent contraction of rat urinary bladder smooth muscle (EC50=2. 9 nM) and a dose-dependent relaxation of rat tail artery smooth muscle (EC50=37. 7 nM).
What are the official names of this protein?
Senegalin.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PBN1_KLULA
Sequence: MSVQTIQSESFIEEKRRITVLLDRDGRSVEEKVVNRDGVITIPNQSGHVQDRAVLFVPQLASRPDFIHISWKRNAEADITPIKSYIPYGFNIFTNSSGSIAKFIDTPVGKVYYSDTFEDNALSKWFPPEFVDQLLRYSEDNDLDITVTRGRVEVNRYYELTDDNLFPLNGTESVKTEAGIFQVDTEDDTDTSLSGLRCTWHTGSGALNKCQRTLFFYNQIYADKSSLSEVSLTLSEPVNLHPVVQIDLTSKRPIHNCEYYAYFNLPKYFFIDQFQSIPTLLFGEHDLELPEYKLSGFGSISLFTLQPGSINEVTLHSRYIKPTNDGSAFFEAAFTPQVFYACDTSIELTKRSPFYTGKIGYEHFFTDNTKFYYLNSTKMTINLPKLDSSDNLCIQLFTLGLVLFSVLYLIRKLF
What is the function of this protein?
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum.  Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis.  Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
What are the official names of this protein?
Protein PBN1.
What is the protein family that this protein belongs to?
Belongs to the PIGX family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type III membrane protein.
Protein: KITH_AYWBP
Sequence: MTQKEQGQGFIEVICGPMFAGKTESLIQRRNKALKLKKKILSFKPRIDDRYSVKEEIVSHNRNNIPAILIDKSKDILTFITPEINVVIIDESQFLDNDIIAIVDYLANCNIEVIISGLELDFCGKPFGPMPYLLAIADTVTKLTSICAISGGKANRTQRLIEGKPAQSNEPVVLVGGKEYHEPRCRKHHCLADIDKTKVNWKNFANQSK
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_ECOSM
Sequence: MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFEGAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_GEOSW
Sequence: MSAIVDVYAREVLDSRGNPTVEVEVYTEDGGFGRALVPSGASTGEYEAVELRDGDKSRYLGKGVLKAVENVNEIIAPAIIGFEVTDQVGIDKTLIELDGTENKSKLGANAILGVSLAVARAAADELDMPLYQYLGGFNAKTLPVPMMNILNGGAHADNNVDIQEFMIMPVGAKSFREALRMGAEIFHSLKAVLKEKGYNTAVGDEGGFAPNLKSNEEALQTIIEAIEKAGYKPGEEVMLAMDVASSELYNKEDGKYHLEGEGVVKTSEEMVAWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLAEGIEKGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDQLGDTAIYNGIKSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PSBC_ORYSA
Sequence: MKILYSLRRFYHVETLFNGTFVLAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVLDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVLKALYFGGIYDTWAPGGGDVRKITNLTLSPGVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGFICVFGGIWHILTKPFAWARRAFVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDLEPVLYMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: EFP_FRAT1
Sequence: MASYSTNEFKGGLKVLIDGNPMVIVENEFVKPGKGQAFNRVKLKNLLNDRVVEKTFKSGESVEAADVEELTTVYSYFDGDSYVFMHPETFEQYMVSEEALGETKKWLKDQDEYQVILFNGQPISIIAANFVNLEIIETDPGLKGDTAGTGGKPATLSTGAVVRVPLFVQTGEIIKVDTRTSTYVSRVKD
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLS_STAA3
Sequence: MTKRKLRNNWIIVTTMITFVTIFLFCLIIIFFLKDTLHNSELDDAERSSSDINNLFHSKPVKDISALDLNASLGNFQEIIIYDEHNNKLFETSNDNTVRVEPGYEHRYFDRVIKKRYKGIEYLIIKEPITTQDFKGYSLLIHSLENYDNIVKSLYIIALAFGVIATIITATISYVFSTQITKPLVSLSNKMIEIRRDGFQNKLQLNTNYEEIDNLANTFNEMMSQIEESFNQQRQFVEDASHELRTPLQIIQGHLNLIQRWGKKDPAVLEESLNISIEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDEIRSRIHSLKQLHPDYQFDTDLTSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKKIKVKTRLKNKQKIIEITDHGIGIPEEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQLNGGSIKIKSEINKGTTFKIIF
What is the function of this protein?
Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence.  ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR (By similarity).
What are the official names of this protein?
Signal transduction histidine-protein kinase ArlS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CC170_HUMAN
Sequence: MSLDCTSHIALGAASPAPEETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH
What is the function of this protein?
Plays a role in Golgi-associated microtubules organization and stabilization.
What are the official names of this protein?
Coiled-coil domain-containing protein 170.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: NOP58_ASPCL
Sequence: MTLFILTETSAGYALLKAKDKKLLKRDDLATEAATAEGVSNLVKLKSFQKFDSAAAALEEVASLVEGKVTPRLASLLDEIKDEKKVSLAVADPKLGNAIGKLPGLDIQLIADSTTADIYRAIREHLPTLIPGLLPQDMSTMSLGLSHSLARHKLKFSPDKIDTMIVQAIGLLDDLDKELNTYAMRVKEWYGWHFPELAKILNDNIAYARLVLKMGMRSNWETSDLAEILPEELEGPVKAAADRSMGTEISQDDLENIQALAEQVVGFAEYRQQLAGYLTARMNAIAPNLTALVGDLVGARLIAHAGSLTNLSKSPASTIQILGAEKALFRALKTKHDTPKYGLIYHASLIGQATGKNKGKMARVLAAKASLGIRVDALADWEDDATEEDKAALGTEARYNLERKLAAMEGKPLKPRGVAIAPNGASAQPKKFELNEARKYNADADALSSDEPKSKKDKKLIEEVSDEEMADADSDEEPAANGTKDDDSSDDSEEEKSKKHKSKKGKDAELEKLAERAGLSLKRYKRKLERGEITFDADGNPTAVSKKDLKKAKKEAKKASKGDEKKRKRSDDGEEVDNAEKKQKKKKKKGEE
What is the function of this protein?
Required for pre-18S rRNA processing.  May bind microtubules (By similarity).
What are the official names of this protein?
Nucleolar protein 58.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NUOD_DESPS
Sequence: MSEHIILNPDETFTLNLGPQHPATHGVLRVKLTMDGEYIYSAETVIGYIHRMHEKMGENRTYNQYLPNLSRLDYLSAMAYCHGYVLAVEKAGSIEVPERAEYIRAITVELNRLSSHLVWFGAFIMDLGGFSPLMYAFDDREQILDLLESITGSRLTYCYYRFGGLYNDIDDEFLVGTRKFIIRMRKSLKTYRDLVTNNIILMKRLKDIGHISPEICRKYGATGPVARGSGINFDVRKNEPYSVYNEFDFDIPVYHEGDSYARYMVRMDEMEQSLRIIEQAMDKLPGGPIIPEKKPKIIKLPEGDYYSTVEAARGSFGIRLVSDGGKNAYRLKLRSPTFSNMHLFDEVCQGMLIADALALMGSLDLVIPEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NINJ2_HUMAN
Sequence: MESARENIDLQPGSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL
What is the function of this protein?
Homophilic cell adhesion molecule that promotes axonal growth.  May play a role in nerve regeneration and in the formation and function of other tissues.
What are the official names of this protein?
Ninjurin-2, Nerve injury-induced protein 2.
What is the protein family that this protein belongs to?
Belongs to the ninjurin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GFAP_PONAB
Sequence: MERRRITSAARRSYISSGEMMVGGLAPGRRLGPGTRLSLARMPPPLPTRVDFSLAGALNAGFKETRASERAEMMELNDRFASYIEKVRFLEQQNKALAAELNQLRAKEPTKLADVYQAELRELRLRLDQLTANSARLEVERDNLAQDLGTVRQKLQDETNLRLEAENNLAAYRQEADEATLARLDLERKTESLEEEIRFLRKIHEEEVRELQEQLARQQVHVELDMAKPDLTAALKEIRTQYEAMASSNMHEAEEWYRSKFADLTDAAARNAELLRQAKHEANDYRRQLQSLTCDLESLRGTNESLERQMREQEERHAREAASYQEALARLEEEGQSLKDEMARHLQEYQDLLNVKLALDIEIATYRKLLEGEENRITIPVQTFSNLQIRETSLDTKSVSEGHLKRNIVVKTVEMRDGEVIKESKQEHKDVM
What is the function of this protein?
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
What are the official names of this protein?
Glial fibrillary acidic protein, GFAP.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with intermediate filaments.