PharMolix/UniProtQA huggingface dataset:
Protein: GUN1_ACIC1
Sequence: MPRALRRVPGSRVMLRVGVVVAVLALVAALANLAVPRPARAAGGGYWHTSGREILDANNVPVRIAGINWFGFETCNYVVHGLWSRDYRSMLDQIKSLGYNTIRLPYSDDILKPGTMPNSINFYQMNQDLQGLTSLQVMDKIVAYAGQIGLRIILDRHRPDCSGQSALWYTSSVSEATWISDLQALAQRYKGNPTVVGFDLHNEPHDPACWGCGDPSIDWRLAAERAGNAVLSVNPNLLIFVEGVQSYNGDSYWWGGNLQGAGQYPVVLNVPNRLVYSAHDYATSVYPQTWFSDPTFPNNMPGIWNKNWGYLFNQNIAPVWLGEFGTTLQSTTDQTWLKTLVQYLRPTAQYGADSFQWTFWSWNPDSGDTGGILKDDWQTVDTVKDGYLAPIKSSIFDPVGASASPSSQPSPSVSPSPSPSPSASRTPTPTPTPTASPTPTLTPTATPTPTASPTPSPTAASGARCTASYQVNSDWGNGFTVTVAVTNSGSVATKTWTVSWTFGGNQTITNSWNAAVTQNGQSVTARNMSYNNVIQPGQNTTFGFQASYTGSNAAPTVACAAS
What is the function of this protein?
Has a very high specific activity on carboxymethylcellulose.
What are the official names of this protein?
Endoglucanase E1, Cellulase E1, Endo-1,4-beta-glucanase E1, Endocellulase E1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: CITXG_LEUMC
Sequence: MDYFEGGERLNLMQVLDNREWREKYQKQLMASFPTAVITSVKLNLPGPIKTSPKLQSVFQIIINDLNPVFKDLQIIKEASFVDQITGPDIFFVTSGCLKLVKQIMITFEESHLLGRLLDLDVMCQNADKQLSREELGFAPRKCLLCGKDAKTCIKEGNHSLAEGYSQINKMLHNFEKSKMIVPQMTQSQVVNAALTGMLYEVSLAPKPGLVDPSSNGAHKDMTVFTFIDSSLALQPYLNEAYRIGNQFKGTDLPRMFSLLRNAGIRAEKDMFAATNGVNTHKGAVFSLGIMVTAVAYATQKGITNLLTIQKVISDMTQDLVKNDLGKNNLRHSQNQQTAGERQFIKYKIPGVRGEAEKGFPIVMNLALPFLCEQQGNLNQRLLNTLMKIAGNIDDTNLIKRAGNATISKDMQHWSVTFFQIGGSYTPEGLKFLNDLDQMFIKRNLSMGGAADNLILTIFLARLVGSL
What is the function of this protein?
Bifunctional enzyme that catalyzes formation of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A, and then the transfer of this prosthetic group precursor to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield the holo-acyl carrier protein.
What are the official names of this protein?
Protein CitXG.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the CitG/MdcB family.
Protein: PB2_I93A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPVTNTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELRDCKISPLMVAYMLERELVRKTRFLPVAGGTSSIYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDSVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYSSSMMWEINGPESVLVNTYQWVIRNWETVKIQWSQNPAILYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQIIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDESTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: DAPA_RHOP5
Sequence: MAATPAFRGSFTALVTPFKNGSLDEEAFRKLVNWQIAEGTTGLVPVGTTGESPTLSHDEHHKVVEWCVEEAKGRVPVIAGAGSNSTTEAVELAKHAEKAGADAVLVVTPYYNKPTQEGMYLHFKAINDAIGIPIIIYNIPPRSVVDMSVDTMSRLYELQNIVGVKDATANLGRVSQQRHAMGPDFIQLSGEDMTALAYMAAGGHGCISVVSNVAPKACSDLMAAVFKGDYAGALKIQDRLVPLHDAVFKEPGVSGAKHGLTLLGRIQEEVRLPLIPVSAPTGQAIRSAMIHAGLLN
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_THETH
Sequence: MKVRASVKRICDKCKVIRRHGRVYVICENPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36, Ribosomal protein B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PSMD2_MOUSE
Sequence: MEEGGRDKTPVQSQQPSATTPSGADEKSSGKERRDAGEKDKEQELSEEDKQLQDELEMLVERLGEKDTSLYRPALEELRRQIRSSTTSMTSVPKPLKFLRPHYGKLKEIYENMAPGENKCFAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVRHLAGEVAKEWQELDDAEKAQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPENSALLRCALGVFRKFSRFPEALRLALMLNDMELVEDIFTSCKDVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIMSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNRFGGSGSQVDSARMNLASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYLYSSEDYIKSGALLACGIVNSGVRNECDPALALLSDYVLHNSNTMRLGSIFGLGLAYAGSNREDVLTLLLPVMGDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNNLFMVRLAQGLTHLGKGTLTLCPYHSDRQLMSQVAVAGLLTVLVSFLDVRNIILGKSHYVLYGLVAAMQPRMLVTFDEELRPLPVSVRVGQAVDVVGQAGKPKTITGFQTHTTPVLLAHGERAELATEEFLPVTPILEGFVILRKNPNYDL
What is the function of this protein?
Binds to the intracellular domain of tumor necrosis factor type 1 receptor.  The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit S2, 26S proteasome subunit p97.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S2 family.
Protein: MTEC_ENTCL
Sequence: MAVGLNKKEIDGPASQRAVACDLEPALPPIGARVTLNYPGKMDESIILQKKDTKYLRVGSDFAKESSLILPNSFIWSDNSLALNRLMVEGKKAKLIYLDPPYATGMGFSSRSNEHAYDDCLTEAAYLEFMRRRLILMREILDDDGTIYVHIGHQMLGELKCLLDEIFGRERFINLITRRKCSSKNSTKNNFANLNDYILCYSKGKKYIWNRPLKKPDAEWLAKEYPKTDSKGQFKLVPIHAPGVRHGATGGEWKGMLPPPGKHWQYTPEKLDILDASGDIHWSKTGNPRRKVYLTDDKSIGYTDYWEEFRDAHHQSILVTGYPTEKNFNMMKLIVGASSNPGDLVIDPFCGSGSTLHAASLLQRKWIGIDESLFAAKTVMKRFAIGRAPMGDYVNTSLNKQTELPLSLNETARHEYVSNDFNIYVDELTASVSKNELAEIQKAYRDLKANQQ
What is the function of this protein?
A beta subtype methylase, recognizes the double-stranded sequence 5'-GGTNACC-3', methylates A-5 on both strands and protects the DNA from cleavage by the EcaI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.EcaI, M.EcaI, Adenine-specific methyltransferase EcaI, Modification methylase EcaI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: MP2K1_PANTR
Sequence: MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVQPSNILVNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERFQGTHYSVQSDIWSMGLSPVEMAVGRYPIPSPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQPSTPTHAAGV
What is the function of this protein?
Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway.  Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation.  RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2.  Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade.  Activates BRAF in a KSR1 or KSR2-dependent manner; by binding to KSR1 or KSR2 releases the inhibitory intramolecular interaction between KSR1 or KSR2 protein kinase and N-terminal domains which promotes KSR1 or KSR2-BRAF dimerization and BRAF activation (By similarity).  Depending on the cellular context, this pathway mediates diverse biological functions such as cell growth, adhesion, survival and differentiation, predominantly through the regulation of transcription, metabolism and cytoskeletal rearrangements.  One target of the MAPK/ERK cascade is peroxisome proliferator-activated receptor gamma (PPARG), a nuclear receptor that promotes differentiation and apoptosis.  MAP2K1/MEK1 has been shown to export PPARG from the nucleus.  The MAPK/ERK cascade is also involved in the regulation of endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC), as well as in the fragmentation of the Golgi apparatus during mitosis (By similarity).
What are the official names of this protein?
Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Cytoplasm. Nucleus. Membrane; Peripheral membrane protein. Note=Localizes at centrosomes during prometaphase, midzone during anaphase and midbody during telophase/cytokinesis. Membrane localization is probably regulated by its interaction with KSR1.
Protein: COPA_STAAM
Sequence: MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVTVETVELDITGMTCAACSSRIEKVLNKMNGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLLTLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLIFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTHYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
What is the function of this protein?
Involved in copper export.
What are the official names of this protein?
Copper-exporting P-type ATPase, Copper-exporting P-type ATPase A, Cu(+)-exporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ROT1_PICGU
Sequence: MWSILWVVTTLISIVAADPNMKELAGTWTSKSNTVFTGPGFYDPVDELLIQPDLPGISYSFTEDGHYEEALYRVTSNSQNHSCATAVLIYQHGTYEILNNGSLVMTPIAVDGRQLLSDPCGYSETESQYTRYVQPTWFKAYYVQVDSYSGKMKLQIYQFDGSLMQPLYLAYSPPLMLPTKALNPTDKASETKSSLRRKVKRSLENQYRTTAVKSFNYEKYDKYWWAAVGVIGIASASVFLH
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
What are the official names of this protein?
Protein ROT1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: MIAA_AQUAE
Sequence: MKILVIGGPTAIGKSDLACCVAQKLNGEIISADSMAVYKFMDIGTAKPLECMKKVPHHLIDVVEPGGYFDAKIFEEMAKEKIEEIKRKGKVPIVVGGTYLYIQALLYGIDETPKPDWNLRNKLYEIARKKGNDYLYEKLKAIDPKYAKKIHKNDLRRIVRALEVFINTGKPFSSFHSWNKPKMDFVGIYLKRSPESLYKRIENRVYDMVKDGLLEEVKKLLEMGYENFLTSGQAIDYKEFVPCAKGEKSLEECIKEAIKNTKKQAKRQIRWFRKQGWHEIDLDKLSIEEACEEVVRIYKDANKTK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MPO1_TOBAC
Sequence: MATTKQKVTAPSPSPSSSTASCCPSTSILRREATAAIAVVGDGLQNWTNIPSVDEKQKKTASSALASLPTTEPLSTNTSTKGIQIMTRAQTCHPLDPLSAAEISVAVATVRAAGETPEVRDGMRFIEVVLVEPDKSVVALADAYFFPPFQSSLMPRTKGGSQIPTKLPPRRARLIVYNKKTNETSIWIVELNEVHAAARGGHHRGKVIASNVVPDVQPPIDAQEYAECEAVVKSYPPFRDAMRRRGIDDLDLVMVDPWCVGYHSEADAPSRRLAKPLVFCRTESDCPMENGYARPVEGIYVLVDVQNMQIIEFEDRKLVPLPPVDPLRNYTAGETRGGVDRSDVKPLHIIQPEGPSFRISGNYVEWQKWNFRIGFTPREGLVIHSVAYLDGSRGRRPIAHRLSFVEMVVPYGDPNDPHYRKNAFDAGEDGLGKNAHSLKRGCDCLGYIKYFDAHFTNFTGGVETTENCVCLHEEDHGMLWKHQDWRTGLAEVRRSRRLTVSFVCTVANYEYAFYWHFYQDGKIEAEVKLTGILSLGALQPGEYRKYGTTILPGLYAPVHQHFFVARMNMAVDCKPGEAHNQVVEVNVKVEEPGKENVHNNAFYAEETLLRSELQAMRDCDPFSARHWIVRNTRTVNRTGQLTGYKLVPGPNCLPLAGPEAKFLRRAAFLKHNLWVTQYAPGEDFPGGEFPNQNPRVGEGLASWVKQDRPLEESDIVLWYIFGITHVPRLEDWPVMPVEHIGFVLQPHGYFNCSPAVDVPPPFACDSESRDSDVTETSVAKSTATSLLAKL
What is the function of this protein?
Involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:17174363, PubMed:17283012, PubMed:16656744).  Amine oxidase which mediates the deamination of N-methylputrescine to produce 4-methylaminobutanal (PubMed:17174363, PubMed:17283012).  Oxidizes preferentially N-methylated amines (PubMed:24287136).
What are the official names of this protein?
N-methylputrescine oxidase 1, peroxisomal, NtMPO1, Copper methylamine oxidase.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: NS1AB_HASV1
Sequence: MAYGEPYYSSKPDKDFNFGSTMARRQMTPTMVTKLPKFVRNSPQAYDWIVRGLIFPTIGKTYFQRVVVITGGLEDGTYGSFAFDGKEWVGIYPIEHLNLMSSLKLIHKANALQERLRLSQEEKATLALDVQFLQHENVRLKEMIPKPEPRKIQMKWIIMGAVLTFLSLIPGGYAHSQTNNTIFTDMIAACKYSTETLTENLDLRIKLALANITISDKLDAVRQILNFAFVPRAHWLRTVFYYIHYYEMWNIFMFVLAIGTVMRSARPGTDLVTLATSHLSGFRMAVLPTIPFHTTMTLWVMNTLMVCYYFDNLLAITLAILAPILGIIFLCFMEDSNYVSQIRGLIATAVLIAGGHACLTLTGTTTSLFVVILTCRFIRMATVFIGTRFEIRDANGKVVATVPTRIKNVAFDFFQKLKQSGVRVGVNEFVVIKPGALCVIDTPEGKGTGFFSGNDIVTAAHVVGNNTFVNVCYEGLMYEAKVRYMPEKDIAFLTCPGDLHPTARLKLSKNPDYSCVTVMAYVNEDLVVSTAAAMVHGNTLSYAVRTQDGMSGAPVCDKYGRVLAVHQTNTGYTGGAVIIDPADFHPVKAPSQVELLKEEIERLKAQLNSATENATTVVTQQPSAALEQKSVSDSDVVDLVRTAMEREMKVLRDEINGILAPFLQKKKGKTKHGRGRVRRNLRKGVKLLTEEEYRELLEKGLDRETFLDLIDRIIGERSGYPDYDDEDYYDEDDDGWGMVGDDVEFDYTEVINFDQAKPIPAPRTTKQKICPEPEVESQPLDLSQKKEKQSEYEQQVVKSTKPQQLEHEQQVVKPIKPQKSEPQPYSQTYGKAPIWESYDFDWDEDDAKFILPAPHRLTKADEIVLGSKIVKLRTIIETAIKTQNYSALPEAVFELDKAAYEAGLEGFLQRVKSKNKAPEKQGPKKLQRAPEDQGAQNYHSLDAWKLLLEPPRERRCVPANFPLLGHLPINRPIFDDKKPRDDLLGLLPEPTWHAFEEYGPTTWGPQAFIKSFDKFFYAEPIDFFSEYPQLCAFADWATYREFRYLEDTRVIHITATEKNTDSTPAYPKMNYFDTEENYLEAHGWAPYIREFTRVYKGDKPEVLWYLFLKKEIIKEEKIRNSDIRQIVCADPIYTRIGACLEAHQNALMKQHTDTSVGQCGWSPMEGGFKKTMQRLVNKGNKHFIEFDWTRYDGTIPPALFKHIKEIRWNFINKDQREKYRHVHEWYVNNLLNRHVLLPSGEVTLQTRGNPSGQFSTTMDNNMVNFWLQAFEFAYFNGPDRDLWKTYDTVVYGDDRLSTTPSVPDDYEERVITMYRDIFGMWVKPGKVICRDSIVGLSFCGFTVNENLEPVPTSPEKLMASLLKPYKILPDLESLHGKLLCYQLLAAFMAEDHPFKVYVEHCLSRTAKQLRDSGLPARLTEEQLHRIWRGGPKKCDG
What is the function of this protein?
Protein covalently attached to the 5' extremity of the genomic and subgenomic RNAs.
What are the official names of this protein?
Non-structural polyprotein 1AB.
What is the protein family that this protein belongs to?
Belongs to the astroviridae polyprotein 1AB family.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: RL3_PROM1
Sequence: MSLGILGKKLGMSQLFDDQGRAVPVTLIEAGPCRITQLKSADTDGYAAVQIGFQLIREKLINKPSKGHLAKSGNDLLRHLREYRVENSSEFELGASITVDDFEKGQKVDVSGDTMGRGFAGYQKRHGFSRGPMSHGSKNHRLPGSIGAGTTPGRVYPGKRMAGRMGGKKVTTRALEILKIDTNHNLLVVKGSVPGKPGSLLNIRPAKRVGVSIQQGGE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: PARG2_CAEEL
Sequence: MDHENLMKYLEEFRSIRFQPDFQKVDAERNVRYCEITDFPISNISFELLETGVSQQWRNCDQNLFNEYLKTYKNGGYSQFEDLLFKIWGYSEEKERFDLPALKSFYRKMSEIVGEDEVLEKLARLVRITKSACEVLPEKIYRLVGDIESATFSHIQCASLIAWMFFSDTPRLSFIIILQKTTCVAVEKLKFLFTYFDKMSIDPPIGAVSFRKMRITHKQYLENWKLRETNLLPDVQVFDKMSIEETALCTQIDFANKRLGGGVLKGGAVQEEIRFMMCPEMMVAILLNDVTQDLEAISIVGAYVFSSYTGYSNTLKWAKITPKHSAQNNNSFRDQFGRLQTETVAIDAVRNAGTPLECLLNQLTTEKLTREVRKAAIGFLSAGDGFSKIPVVSGWWGCGAFRGNKPLKFLIQVIACGISDRPLQFCTFGDTELAKKCEEMMTLFRNNNVRTGQLFLIINSIGPPLNYSEQYVFDAIRAKINSTKA
What is the function of this protein?
Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:17188026).  Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells (By similarity).
What are the official names of this protein?
Poly(ADP-ribose) glycohydrolase 2, Poly ADP-ribose metabolism enzyme 4.
What is the protein family that this protein belongs to?
Belongs to the poly(ADP-ribose) glycohydrolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_BURMS
Sequence: MNAAVIDSHSAQDYVVADIALAGWGRKELNIAETEMPGLVQIRDEYKAQQPLKGARIAGSLHMTIQTGVLIETLKALGADVRWASCNIFSTQDHAAAAIVEAGTPVFAFKGESLDEYWEFSHRIFEWPNGEFANMILDDGGDATLLLILGSKAEKDRSVIARPTNEEEVALFKSIERHLEIDGSWYSKRLAHIKGVTEETTTGVHRLYQMEKDGRLPFPAFNVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKADIFVTATGNYHVINHDHMKAMRHNAIVCNIGHFDSEIDVASTRQYQWENIKPQVDHIIFPDGKRVILLAEGRLVNLGCATGHPSFVMSNSFTNQTLAQIELFTRGGEYANKVYVLPKHLDEKVARLHLARIGAQLSELSDDQAAYIGVSKAGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_ARTS2
Sequence: MANYTAADIKALRERTGAGMMDVKKALDEANGDAEKAIEIIRIKGLKGATKREGRSTAEGLVAAKVAGGVGVMIEVNCETDFVAKADKFIQLADKVLAVAVESGAADIETLLATEVDGKPLSEVVVEEGAILGEKVVVRRISRLEGGTVDAYLHKTSKDLPAQVGVLFAVDGEGEAAATAAHDVAVHIAAMAPNYLTREDVPADLVESERRIAEETAKAEGKPEAAMTKIVEGRVTGFYKGEVLVDQAFAKDAKKSVAQVLEEAGVKGTAFARFRVGS
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIK_BUCAP
Sequence: MFKYSDNIALEGKLSDNQNNNLTSLNFFSKSNINAFKKLFINKGIEFDNVSTKKKKEEDKNIPSINFVITNLINILNKKDTMLKETMLNHIAKKNYKCRNIQRKNKDKNFKLKKYIKLDIETKNETKKNQKYKKFIVHPIFKKSIEIKNQSNEFKQINIFHNFNDKFFFRKDRYSNIKSNKSIFSDNKILRCFRNFRKNTPDLFFLKNINKISNVTTYETNTFKDNNNKKHLKCVNSSLELLNSKKNDKWKQVINHQILLSISNKENKAEISFTPEYLGSIHIKIKMRNDQATLNFISNHDEVKVFLKNCIPFLKNSLMKNGIQLEKINIYNSSFSKNHISQKNKRIVKNYFFHGNEFKKTFNFQENYMKLIQYKSIDMYI
What is the function of this protein?
Controls the length of the flagellar hook.
What are the official names of this protein?
Flagellar hook-length control protein.
What is the protein family that this protein belongs to?
Belongs to the FliK family.
Protein: TRA1_CAEBR
Sequence: MMAPSTEDPETVVEAQRRGSFSKKNGNGWTKPGLANGSESKHMEPVTGTNALMAAIDADDQETKLKDPLEKEASTYKSATDRFFQSSHPPSHQTVENPIKLEPPTSSGVTQNGSPVTNSLVPEAAQPLQTVAESSEPTAASAEPTDASSAESSTITVTPVVPVVKFTNQTTPNGSTVATSVGQNVRLTINGKRVGRPPGTFKRPPNNPTTNTSHGEETDSEASTDLICRWKDCMLKFANLKGLVEHVQEKHVQSTEQEHHAWRCEWEGCDRNETFKALYMLIVHVRRHTGEKPNKCEYPGCGKEYSRLENLKTHRRTHTGEKPYKCEFSDCEKAFSNASDRAKHQNRTHSNLKPYSCQIGGCQKSYTDPSSLRKHIKAVHGDEEYEKAKKSRPPNYSNRRRPDHRMPPPTSAMSHPYLAPPHVLPPVAAPGVHQQNFINLALAQHHHNQRAQFIANNAALMDPNGSGAAQAAAAAQAAQAQQAQMYQAQAMQQHQFAAQMQQQAVMQVHMQQAALQQAQVAIIQNNLLSTQGIMNQFPMMSPLLTPRAPGNVMSLLQQQQVTPPTPTMMQLTPHTPITPITPITPLTPMGATTGPMFSMPNIMMTTPVRMDIPTSVPAAVPVAPVAPVAPVAPAAPVAPPASSLAEATEPRFRLLRQHMEGAEVAPVLAPQQPLEEDDDMTDDEESGNVAPAVIRNGDGPDDRNSGTGSSSPRSSASSGSGTLEVAGSVAQNGNRSSSTGERGMRSFLIADILQMAHDFQNGRIITDALHKAIFDTSDVTAMFHIYRTFECVCEYLQFTFSAGERLPTWPEVRTIHEYYHSDYDRTRFHASETVRRRDNLFWRFVNYCNSDLPIGGRPILSVSYDEGFEESIDQGSNFGTIPQQLISRMAAEAFDDEDDGFDDAFDIPGLRLGGVEVLIQQQRHRVRRAALKQAQIDYPTAEEDLGYVGGGFGQEDDDHHSYAIYEQQKTVAFVDLSEKPKVEVLTDEDFMEQFKAAEARCQARLAIEPMVKVARTVINGKVVEYTESQLFSPPVSRRTIYSMLKQFPEHQENLLKFITLHVDKCELENVIPSREYMSDMESSFFAHHRIVRAALRARGEITEAEEAEYQQSSNLMYNQDFAALMFPELDESHDDFLNDLPISSRRRSSDSDSKEAPSMKKPRSF
What is the function of this protein?
Plays a major role in controlling sexual phenotype (PubMed:18245372).  Terminal global regulator in a well-characterized cascade of sex-determining genes (By similarity).  Promotes female development (By similarity).  Interacts with tra-2 to promote spermatogenesis (PubMed:11250902).  Promotes spermatogenesis through the Tip60 HAT complex and by regulating the expression of genes, such as fog-3, required for male development (PubMed:24098152).  Association with chromatin and at the fog-3 promoter requires wdr-5. 1, and may also require wdr-5. 2 (By similarity).  With trr-1, activates the fog-3 gene to determine sperm/oocyte cell fate (PubMed:24098152).  In hermaphrodites, binds to an intronic regulatory site in the ceh-30 gene, preventing ceh-30 transcription and thereby preventing survival of the CEM (cephalic male) sensory neurons (By similarity).  Represses the expression of the transcription factor dmd-3 in hermaphrodites to govern the timing and extent of male tail tip morphogenesis (By similarity).  Plays a role in controlling the sex-specific differentiation of PHC sensory neurons and represses the development of male-specific morphological features (By similarity).
What are the official names of this protein?
Sex-determining transformer protein 1, Cbr-tra-1.
What is the protein family that this protein belongs to?
Belongs to the GLI C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localization with chromatin in the nucleus in part depends on normal function of wdr-5.1.
Protein: RLMH_YERPN
Sequence: MKLQLVAVGTKMPDWVQTGFIEYLRRFPKDMPFELAEIPAGKRGKNADIKRILEKEGELMLAAVGKNNRIVTLDIPGTPWETPQLAQQLERWKQDGRDVSLLIGGPEGLAPACKAAAEQSWSLSPLTLPHPLVRVLVAESLYRAWSITTNHPYHRE
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.