PharMolix/UniProtQA huggingface dataset:
Protein: TRHO_SALSV
Sequence: MPVLHNRISNDELKAKMLAESEPRTTISFYKYFTIASPQQTRDALYQVFTALDVFGRVYLAHEGINAQISVPQSKLETFRQQLYTFDPALDGLRLNIALEDDGKSFWVLRMKVRDRIVADGIDDPTFDASNVGDYLKAADVNAMLDDPDAVFIDMRNHYEYEVGHFENALEIPADTFREQLPKAVEMLREHADKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARRAREQGLPVRFIGKNFVFDERMGERISDEVIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPQCASKFNGCCSEQCCEELALPEEEQRRRRAGRENGNKIFNKSRGRLNSKLSIPDPAE
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: NS1_INCJH
Sequence: VKSTNLMAFVATKMLERQEDLDTCTEMQVEKMKTSTKARLRTESSFAPRTWEDAIKDGELLFNGTILQAESPTMTPASVEMKGKKFPIDFAPSNIAPIGQNPIYLSPCIPNFDGNVWEATMYHHRGATLTKTMNCNCFQRTIWCHPNPSRMRLSYAFVLYCRNTKKICGYLIARQVAGIETGIRKCFRCIKSGFVMATDEISLTILQSIKSGAQLDPYWGNETPDIDKTEAYMLSLREAGP
What is the function of this protein?
Suppresses the RNA silencing-based antiviral response in Drosophila cells.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1C.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: PSBP_CUCSA
Sequence: MASTSCFLHHHALTAAARSSSSPRQAALPKSPQLLVCRAQKQQPAQEEEGGVVSRRLALTVLIGAAALGSKVSPADAAYGEAANVFGKPKSNTDYLPYSGDGFKLSIPSKWNPSKEREFPGQVLRYEDNFDSNSNLSVIINPTDKKSIKDFGSPEEFLSKVDYLLGKQAYFGKTASEGGFDPDAVATANILEATASNVNGKDYYFVSVLTRTADGDEGGKHQLITATVNDGKLYICKAQAGDKRWFKGARKFVEGAASSFSVA
What is the function of this protein?
May be involved in the regulation of photosystem II.
What are the official names of this protein?
Oxygen-evolving enhancer protein 2, chloroplastic, OEE2, 23 kDa subunit of oxygen evolving system of photosystem II, 23 kDa thylakoid membrane protein, OEC 23 kDa subunit, OEC23.
What is the protein family that this protein belongs to?
Belongs to the psbP family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane. Note=Associated with the photosystem II complex.
Protein: Y1627_BACCQ
Sequence: MKVIAVTGYKPFELGIFKNDHPGVECIKKALRRKLTAFVEDGLEWVIISGQLGVELWAAEVVFEIQVEYPDLKLAVFTPFLEQEEGWKEDNREYYEFILSQADHVDSITKRKYESPEQFKLKNQFFIEKSDALLAVYDEEKPGSPKYIVEAAKKKGEIENYHSYFILFSDLQDIIEEEQWNNAE
What are the official names of this protein?
UPF0398 protein BCQ_1627.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: BTSL2_ARATH
Sequence: MGGGNLHSLPPENASVSASYAVTVGNTKLSDAPVLFFVYCHKAFRAQLVELRRFATDAAEADSFSGDLAVELSRKFEFLKLVYKYHSAAEDEVIFLALDKRVKNIVSNYSLEHAGTDDLFTSIFHWLHVLEEEIGSRSDVLREVILCIGTIQSSICQHMLKEERQVFPLLIEKFSFREQASLVWQFICSVPVMVLEDFLPWMISHLSHEEKIEVENCIKDVAPNEDSLQQVISSWLLDDSQSSCGTPTEIMKGVQYVNVSKSLKKSPESHPSSGCFQRFWEWSKKSLSIPNVGRSPIHGLRLFQNAIEKDLRDIQEGLCQAKFQTLILDLDVLMARLNFLADVLVSYSNAFKKFFHPVLEEMTARRSSTAKQFNIDDCLENFQRLLYKSADDKTKTDNFLLQLQEELESLIIQVTKQFAIQRTEVFPIISKNCNHEMQKQLLYTSIHVLPLGLLKCVILWFSAHLSEEESQSILHFLSLEDSSPKKSFPRLLLQWLRFGYSGKTSVERFWKQLDVMFKVRCSCQKEHTEEASGSFSNQTQLQLCKVSKDVYPRKKDKSSTCFMSMDLAVGDMYETPYSSRMNQQMTFSGKLKPPLHLPDFFGEKNMDDPMIMDVKPIDLLFFFHKAMKMDLDYLVCGSTRLAADFRFLAEFQQRFHMIKFLYQIHSDAEDEIAFPALEAKGQLKNISHSFSIDHELETKHFDKVSFILNEMSELNMLVSTINTTAADHDRKMKYERLCLSLREICKSMHKLLSEHIQHEETELWGLFRNCFSIEEQEKIIGCMLGRISGEILQDMIPWLMESLTSDEQLAAMSLWRQATRKTMFVEWLTEWYNGHVLQEEAGEANNDPFGDSDPLEIVWKYLFEASADGEKGSMRSSLLKLPKTNFTGIMNQPPPNYKVEVGKKEEKDLERSESKKICRGSNQEGDKEQTDKMSQKVSQFGPSKKYEQLLTMSEEELVVVIKKISCDSSLDPQKKDYIKQNLLMSRWNISQRTYNLEPSSLSSNMETVHGQHPSYRDPHSLIFGCNHYKRNCKLLAPCCDKLFTCIRCHDEEADHSVDRKQITKMMCMKCLLIQPIGANCSNTSCKSSMGKYFCKICKLYDDERKIYHCPYCNLCRVGKGLGIDYFHCMKCNACMSRTLVEHVCREKCLEDNCPICHEYIFTSSSPVKALPCGHLMHSTCFQEYTCSHYTCPVCSKSLGDMQVYFKMLDALLAEEKMPDEYSNKTQVILCNDCGRKGNAPYHWLYHKCTTCGSYNSRLL
What is the function of this protein?
Probable E3 ubiquitin-protein ligase that may regulate the response to iron deficiency and thus contributes to iron homeostasis.
What are the official names of this protein?
Zinc finger protein BRUTUS-like At1g74770.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Nucleus.
Protein: HBB_NYCCO
Sequence: VHLTGEEKSAVTALWGKVNVDDVGGEALGRLLVVYPWTQRFFESFGDLSSPSAVMGNPKVKAHGKKVLSAFSDGLNHLDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVVVLAHHFGKDFTPQVQSAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LIPA_SALA4
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVVTERDALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDAEEPQKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIRAKSPEIKIETLVPDFRGRMDRALDILNATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPEEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELU_SALEP
Sequence: MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFIRMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGTWQEVANWLKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: G6PI_BUCAI
Sequence: MKNINFNNTQSYQDLKNHFRKIKNIHLRDLFASDLNRFKKFSIIFENEMLIDFSKNRITDETLIYLLNLAKETDVKSGIKLMFSGAKINKTENRSVLHIALRNRTNRPIILNNCNIMLEVNALLEKMKNFSKMVIHGEWKGYTGKSISNVVNIGIGGSDLGPYMVTEALRPYKNHLNMYYVSNIDGTHLTEVLKKINPENTIFLIASKTFTTDETITNAHSAKKWFLHYSQDQSALDKHFFALSANIKNALNFGININNIFKFWDWVGGRFSLWSSAGLSIMLSIGFDNFEKFLDGAHAMDNHFYHTNYKENIPILLALISIWYTNFFGSETEAIFPYDQYMHRFSAYFQQSNMESNGKSINRNGQRINYQTGPIIWGEPGTNGQHAFYQLIHQGTRLIPCDFIAPVFSHNDLNNHHMKLISNFFAQTQALAFGQSRDSILHRLILSKKNQDDIKRILPFKICKGNQPTNSILIRKITPYNLGALIALYEHKIFVQGYILNIFSFDQWGVELGKELSQNIYNYLNINVKNKSYDASTEGLINFYKSFMI
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPU_HV1AN
Sequence: MHHRDLLAIIIISALLFINVILWGFILRKYLEQKEQDRKEREILERLRRIREIRDDSDYESNGEEEQEVMDLVLSHGFDNPMFEP
What is the function of this protein?
Enhances virion budding by targeting host CD4 and Tetherin/BST2 to proteasome degradation.  Degradation of CD4 prevents any unwanted premature interactions between viral Env and its host receptor CD4 in the endoplasmic reticulum.  Degradation of antiretroviral protein Tetherin/BST2 is important for virion budding, as BST2 tethers new viral particles to the host cell membrane.  Mechanistically, Vpu bridges either CD4 or BST2 to BTRC, a substrate recognition subunit of the Skp1/Cullin/F-box protein E3 ubiquitin ligase, induces their ubiquitination and subsequent proteasomal degradation.  The alteration of the E3 ligase specificity by Vpu seems to promote the degradation of host IKBKB, leading to NF-kappa-B down-regulation and subsequent apoptosis.  Ion channel activity has also been suggested, however, formation of cation-selective channel has been reconstituted ex-vivo in lipid bilayers.  It is thus unsure that this activity plays a role in vivo.
What are the official names of this protein?
Protein Vpu, U ORF protein, Viral protein U.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPU protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: EABF_STRCX
Sequence: MSRIRWRYGTAATALLVAAGLVPTATAHAEDVTDYSITVDPAAKGAAIDDTMYGVFFEDINRAADGGLYAELVQNRSFEYSTDDNRSYTPLTSWIVDGTGEVVNDAGRLNERNRNYLSLGAGSSVTNAGYNTGIRVEQGKRYDFSVWARAGSASTLTVALKDAAGTLATARQVAVEGGWAKYRATFTATRTSNRGRLAVAANDAAALDMVSLFPRDTYRNQQNGLRKDLAEKIAALHPGFVRFPGGCLVNTGSMEDYSAASGWQRKRSYQWKDTVGPVEERATNANFWGYNQSYGLGYYEYFRFSEDIGAMPLPVVPALVTGCGQNKAVDDEALLKRHIQDTLDLIEFANGPATSKWGKVRAEMGHPRPFRLTHLEVGNEENLPDEFFDRFKQFRAAIEAEYPDITVVSNSGPDDAGTTFDTAWKLNREANVEMVDEHYYNSPNWFLQNNDRYDSYDRGGPKVFLGEYASQGNAWKNGLSEAAFMTGLERNADVVKLASYAPLLANEDYVQWRPDLVWFNNRASWNSANYEVQKLFMNNVGDRVVPSKATTTPDVSGPITGAVGLSTWATGTAYDDVKVTAADGATLLSDDFSGDASKWTHTGAGSWSVQDGQYVQTDAAAENTMVQAGDPSWHDYDLHVKATKKSGKEGFLVAFGVKDTGNYYWWNLGGWNNTQSAVEQAVDGGKGTLLTKAGSIETGRAYDIDVKVRGRQVTLYLDGQEWGGFTDDKPAEPFRQVVTKDARTGDLIVKVVNAQPAEARTAIDLGGARVASTARVTTLAADQDAVNTETDAPVTPATSTFSGVTDRFTYTFPANSVTFLRLKQR
What is the function of this protein?
Involved in the degradation of arabinan and is a key enzyme in the complete degradation of the plant cell wall.  Catalyzes the cleavage of terminal alpha-L-arabinofuranosyl residues of arabinan present in the arabinofuranosyl polysaccharides or oligosaccharides.  It cannot act on other arabinose-containing polysaccharides and arabinoxylo-oligosaccharides.  It leaves most of the polymer intact, including most of the main-chain residues and the arabinose side chains.  It acts preferentially on the linear alpha-(1->2)-linked arabinofuranobiosides and alpha-(1->3)-linked arabinofuranobiosides, and is much less effective on alpha-(1->5)-linked arabinofuranobiosides.  It also hydrolyzes the terminal alpha-(1->3)-linked arabinofuranotriosides in preference to the alpha-(1->5)-linked arabinofuranotriosides.
What are the official names of this protein?
Extracellular exo-alpha-L-arabinofuranosidase, ABF, Alpha-L-AFase, Extracellular arabinan exo-alpha-L-arabinosidase, Arabinosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 51 family.
What are the subcellular locations of this protein?
Secreted.
Protein: LEU3_STAAB
Sequence: MTYNIVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFGGASIDTFGEPLTEKTLNACKRADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFANIRPTTVFKGASSLSPLKQERVEGTDLVIVRELTSGIYFGEPRHFNNHEALDSLTYTREEIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVSQLYPEVTVNHLLVDACSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRLYEPIHGSAPDIAGKNVANPFGMILSLAMCLRESLNQPDAADELEQHIYNMIENGQTTADLGGKLNTTDIFEILSQKLNH
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYY_NEIM0
Sequence: MSVIQDLQSRDLIAQTTDIEALDALLNEQKIALYCGFDPTADSLHIGHLLPVLALRRFQQAGHTPIALVGGATGMIGDPSFKAAERSLNSAETVAGWVESIRNQLTPFLSFEGGNAAIMANNADWFGKMNCLDFLRDIGKHFSVNAMLNKESVKQRIDRDGAGISFTEFAYSLLQGYDFAELNKRYGAVLEIGGSDQWGNITAGIDLTRRLNQKQVFGLTLPLVTKSDGTKFGKTEGGAVWLNAKKTSPYQFYQFWLKVADADVYKFLKYFTFLSIEEIDAVEAKDQASGSKPEAQRILAEEMTRLIHGEEALAAAQRISESLFAEDQSSLTESDFEQLALDGLPAFEVSDGINVVEALVKTGLASSNKEARGFVNSKAVLLNGKPAEANNPNHAAERPDDACLLTDEHKRFGKYTILRRGKRNHALLVWK
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_COLP3
Sequence: MAHVIDLQVACTPTKLPTKEQFQLWVDTALAEVSSSPNQDFELTIRLVNNEESQQLNKQYRDKDKPTNVLSFPFEVPDGIELNLLGDLIICIEVMKQEAQEQNKALFEHWAHLVIHGCLHLVGFDHISDTEALEMESIEITILEKLGISNPYLEQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_PSEF5
Sequence: MIGRLRGTLAEKQPPHLILDVNGLGYEVEVPMTTLYRLPSVGEPLTLHTHLVVREDAQLLYGFASKRERDFFRELIRLNGVGPKLALALMSSLEVDELVRCVQAQDTSALTKVPGVGKKTAERLLVELKDRFKAWEAVPSMFALVPNQPDAPAPVASAESDAVSALISLGYKPQEASKAVSAIKDKGLSSEDMIRRALKGMI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PLSB_PSEA7
Sequence: MPRYPFRRFGFGALRRLLYLWVRSETINQSAFTLKIDRSKPVLYVLQQPSVSDLAVVDTECRKAGLPRPVMPVAVGDAIEPAAFFYLTPEPDWLGRQDKRGASPTLVRMLAAVGQNGLDDAQIIPVSVFWGQSPDSESSPWKLLFADNWAVTGRLRKLARILILGRKTRVQFSAPIHLRELVEQGKGHERTLRMVNRILRVHFRNLKTAVIGPDLSHRRNLVKGLLRAPLVRQAISEECESERISQEKAEGIALRYANEIASDFSYPVIRFLEVILSWFWNKLYEGVKVNHIERVQDVAQGNEIVYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGSILRRGGAFFMRRSFKGNQLYTAVFNEYLHTLFSRGFSTEYFVEGGRSRTGRMLHPRTGMLAITLRSFLRDSRRPIVFVPVYIGYERVLEGRTYLGELRGATKKKESIFDLFKVVGALKQRFGQVWVNFGEPIHLDQFLDRHQPDWQDQDLGPEYRPDWLPQTTNLLAKDVARHLNDAAAINPVNLVALALLSTSRQALDESALARILDLYLALLRQVPYSPSATLPDGDGQALIEYVKSMNLLAEQKDALGRILYLDEQNAVLATYYRNNVLHVFALPALIASFFQSNSRISREQLLRFARALYPYLQAELFIRWSLDELDAVIDQWLAALVEQGLLRQENDTFIRPAPSSRQYVLLILLARSVTQTLQRFYMAIALLLNAGQNALTAEELENLCTVMAQRLSILHGLNAPEFFDKSLFRHFIQTLLDLRVLRKDETGKLSYHELLGELAEGAAKRVLPAEIRLSIRQVALERPAEEAAAESNDAATN
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CIAO1_DROWI
Sequence: MGRLILEHTLQGHKGRIWGVAWHPKGNTFASCGEDKAIRIWSLSGNSWSTKTILSDGHKRTIREIRWSPCGQYLASASFDATTAIWSKSSGEFECNATLEGHENEVKSVSWSKSGGLLATCSRDKSVWIWEVAGDDEFECAAVLNPHTQDVKRVVWHPTKEILASASYDNTIKMFAESALDSDWDCTATLSSHTSTVWSIDFDADGERLVSCSDDTTLKIWRAYHPGNDAGVATPDKQTVWKCVCTLSGQHSRAIYDVSWCKLTGLIATACGDDGIRIFKESSDSKRDEPTFEQVTAEESAHEQDVNSVEWNPVMAGQLISCSDDGTIKIWKMLD
What is the function of this protein?
Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery.  Required for the maturation of extramitochondrial Fe/S proteins.
What are the official names of this protein?
Probable cytosolic iron-sulfur protein assembly protein Ciao1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat CIA1 family.
Protein: NRDR_ACIAD
Sequence: MHCPFCNAADSKVIDSRLAAEGCQIRRRRECISCGERFTTFESYEVVMPRVIKSNGKNEPFDEAKLRRSLMHALQKRPVTQEQIEAVLSDIQLKIRRLGERDVKSRMIGEIVMQALFALDHVAYVRFASVYQDFQDVEAFRRQIEQMQQREQECEKHDV
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: FA9_CHICK
Sequence: MAKIPLILSFCLLEAFLGAESTVFIENKEASTVLSRTRRGNSNRLEELIPGNLERECIEEKCSFEEAREVFENTEKTMEFWKIYIDGDQCNSNPCKNGAVCKDGVSSYECMCPPGYGGRNCEIDSTCATKNGGCEHFCRHDTPQKAVCSCASGYKLHEDGKSCKPAVPYPCGRITAPEMRGKVTRTENTIERWNITAHDEGDAHDEALDITEPPPPPTTSAAPAKIVPITKNDTRVVGGYDSVKGQLPWQVHLVDSRGLGFCGGSIINEKWVVTAAHCLEPGDNVTAVAGEYNTKEDDHTEQRRQVVKILPYPTYNRTRNKHHNDIALLELDQPLTFNSYVTPICIGSRDFTNNLLSNGPGTVSGWGSMLYRGRSAIVLQVLTVPFVDRVTCLKSTSTTILHSMFCAGYTAGGKDTCGGDSGGPYTNSIGETWFLTGVTSWGEECAKPGKYGIYTKVAKYVKWIRETTRLT
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HCP_METMA
Sequence: MFCNQCQEALNVIGCTKNGVCGKKGEVADLQDRLLYVLKSVSYYNLKARELGLNEETADKIVLDAFFATLTNTNFDKQAIESYIKKGFEIRDSIKAKLPAGTLPAEEDLPDVAKVTPENITGMDVAVHSTQNEDVRSLRELLTYGMKGMAAYAHHAYILGYKDEEIFKFIEKGLVATTDDTIGVDDLIGLVLECGQKGVSVLALLDKANTETYGSPEPTAVNIGVRGNPGILISGHDLLDLEQLLEQTKGTGIDVYTHGEMLPANSYPAFKKYDNFAGNYGNAWWRQNEEFEKFNGPVLMTTNCIIPPRESYRNRIYTTGVVGFEGLPHIHEKEDGTKDFTSLIEQAKMSKPPEQLESGTIMGGFAHEAALSVADKIIDAVKTGKISRFMVMAGCDGRHKERAYYTEFAKALPENTVILTAGCAKYRYNKLDLGDIGGIPRVLDAGQCNDCYSLVVIAQKLAEAFGLEDINDLPISYNIAWYEQKAVLVLLALLSLGVKNIVLGPTLPAFVSPNVLKVLVDNFNIRPNTTVEEDMKVLLG
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_PSYWF
Sequence: MAGNSIGQAFKVTTCGESHGAGLMAIVDGVPSGLPLTSEDLQLDLDRRKPGTSKFATQRREPDEVEIISGVFEGKTTGTSIGLLIRNTNQKSKDYSDIKDTFRPGHADYTYSMKYGFRDYRGGGRSSARETAMRVAAGAIAKKYLKQRLGIEIHGHVVLMGNEAAAVTDPNQIDWQFVNSNPFFCADPDALPRFEALIERLRKEGTSCGAKLEVIASGVPVGLGEPVFDRLDADIAHAMMSINAVKGVEIGDGMRVAEQFGHIARDELTPDGFTANHSGGILGGISSGQDIKVSIALKPTSSITTPGKSIDQQGQPVDMLTKGRHDPCVGVRATPIAEAMLAIVLLDHYLRHRGQNADVTQPVAPIA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: H9B01_CYRHA
Sequence: MKSIVFVALFGLALLAVVCSASEDAHKELLKEVVRAMVVDKTDAVQAEERECRWYLGGCSQDGDCCKHLQCHSNYEWCVWDGTFSK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
Omega-theraphotoxin-Hhn1a 1, Omega-TRTX-Hhn1a, Hainantoxin-IX-2, HNTX-IX-2, Peptide F1-30.82.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 17 (Hntx-9) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GEDH_ASPTN
Sequence: MANPAVGAMMGLSLVAVPVFLDTNTQSEQLLAQFASLYDYGHKLMPTIAVATCALHGWVAARKRAAHQPWGRPVLAAVTTITMVPFTWVCMVSTNNALFQLHKGADANMEMVRALIARWQWLHVARSLFPLAGAIVACQTLLKELVGGSR
What is the function of this protein?
Anthrone oxygenase; part of the gene cluster that mediates the biosynthesis of geodin, an intermediate in the biosynthesis of other natural products (PubMed:7665560, PubMed:19549600, PubMed:24009710).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) gedC (PubMed:12536215, PubMed:19549600).  The atrochrysone carboxyl ACP thioesterase gedB then breaks the thioester bond and releases the atrochrysone carboxylic acid from gedC (PubMed:19549600).  The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (PubMed:24009710).  The next step is performed by the emodin anthrone oxygenase gedH that catalyzes the oxidation of emodinanthrone to emodin (PubMed:1810248).  Emodin O-methyltransferase encoded probably by gedA then catalyzes methylation of the 8-hydroxy group of emodin to form questin (PubMed:1444712).  Ring cleavage of questin by questin oxidase gedK leads to desmethylsulochrin via several intermediates including questin epoxide (PubMed:3182756).  Another methylation step probably catalyzed by methyltransferase gedG leads to the formation of sulochrin which is further converted to dihydrogeodin by the sulochrin halogenase gedL (PubMed:24009710).  Finally, the dihydrogeodin oxidase gedJ catalyzes the stereospecific phenol oxidative coupling reaction converting dihydrogeodin to geodin (PubMed:7665560).
What are the official names of this protein?
Anthrone oxygenase gedH, Geodin synthesis protein H.
What is the protein family that this protein belongs to?
Belongs to the anthrone oxygenase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IF2_PARPJ
Sequence: MASNNVAQFAAELKMPAGVLLEQLQAAGVTKASEDDSLSETDKARLLDHLRKSHGSTDADKRKITLTKRHTSEIKQSDATGKARTIQVEVRKKRTFVRRDETSAENGDASNHVAEADVDDLELQRREEEARHEAELLEKQAQELKARQEQLEREEAERQAREAAAEAERRRAEEEAAKKRAAAEAAAREQAQAAKPAQAAQPAAAKAEPVAAKAAEPAVAKQSEQDDERAAAERAAQREAAKKAEDAARQAAEKARAEQEQIAKRRAAAEAEARAIREMMNTPRKAQVKAPEPAPKPAEPAKAAEAKGTLHKPARPAGEAPSRPAAKKPAAAAPAATTTPSAGDKKKPGGGKGGWQDDAAKRRGIKTRGDTSGGVDRGWRGGPKGRGKHQDQNTTFQAPTEPIVREVHVPETITVADLAHKMAVKASEVIKSMMKLGQMVTINQMLDQETAMIIVEELGHHAVAAKLDDPEAMLVEGEISDAESLPRPPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETPRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAGGVPLVVAINKIDKPDANPDRVKQELVAEGVVPEEYGGDSPFVSVSAKTGAGIDDLLENVLLQAEVLELKAPVEAPAKGLVIEAKLDKGKGPVATILVQSGTLNRGDVVLAGSAYGRVRAMLDETGKPTKSAGPSIPVEIQGLSEVPQAGEEVIVMPDDRKAREVALFRQGKFRDVKLAKQQAAKLENMLEQMGEGEVAYMPLIVKADVQGSQEALVQSLLKLSTDEVRVQIVHGAVGGISESDVNLATASKAVIIGFNTRADAQARKLAEANGVDIRYYNIIYDAVDEVKAAMSGMLAPEKREIVTGTVEVRQVFKVPKIGAVAGCMVTDGFVKRSSSVRVLRNNVVIFTGELDSLKRFKDDVKEVRQGFECGMSIKNFNDIVEGDQFEVFEITEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.