PharMolix/UniProtQA huggingface dataset:
Protein: YBEY_CHLCV
Sequence: MKKVSIQVCISNKQNDVPIRIQSAKKLVLYCLQHWEVHTDQVYIYFLDDESLAQLHDEVFSDPSLTDTITLPIDSPGTSSQPHILGEAFISPKAAIRFLKDRAEDSDLLYEEISRYVIHSLLHMLGYDDQTPEERKKMRVKENQALCMLREKHALLSD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_SYMTH
Sequence: MAPGYQPPSPEEKEQYVRELFDKIAENYDAMNQVMSAGQWEKWHREFVAQTHFRPGDHILDVACGTGDLTLLDAAQVAPDGKVIGVDISEGMLEVGRRRVAASPYKDLITLQLGNAMDLPFPDNTFDGVTMGWAMRNVASIPRTLSEIYRVLKPGGRFICLEASKPFSRFIRFGFFVYWKTFLPLIDWFVVKAGRQAKVRPYTYLSRSLDNYPFPDQLEELFREAGFVETDYQLLMLGTVAIHVGTKRREG
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: YPEL1_MOUSE
Sequence: MVKMTKSKTFQAYLPHCHRTYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGW
What is the function of this protein?
May play a role in epithelioid conversion of fibroblasts.
What are the official names of this protein?
Protein yippee-like 1, DGL-1, Mdgl-1.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DADA_BURCM
Sequence: MRVVVLGSGVVGVASAYYLARAGHEVTVIDREAGPALETSFANAGQISPGYAAPWAAPGVPLKAVKWMFEKHAPLAIRLDGTRFQLQWMWQMLRNCTADRYAVNKGRMVRLAEYSRDCLQALRADTGIQYEGRTGGTLQLFRTQQQLDGAAKDIAVLQEANVPFELLSPAELKNAEPALAAVSHKLTGGLRLPGDETGDCQLFTTRLAALAESLGVKFRYNTPIDSLAIAGGRIAGVQCGSETVRADAYVVALGSYSTSFISNLMKIPVYPLKGYSITAPIVNDAAAPVSTVLDETYKIAITRFDQRIRVGGMAEIVGFDKNLRAARRETLEMCVNDLFPGGGDTSKATFWTGLRPMTPDGTPIVGRTPVSNLFLNTGHGTLGWTMSCGSGQLLADLISGKKPAIQADDLSVHRYLKDVAGQTRPAYA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: Y1627_PYRAE
Sequence: MVDKLLNATLNVVKNRGEQLFIDVARPYAYTLVAKFDRDKYIMRVATDAEQVSQSAIKDLKLLSIHTNAPSICVVSSVKGHLLQRGVVYLRDDVVFMSLATLTDVLEGKKPIFKLNRGVITASIDGEKLRAKRQQAGLSLGTLATNLGVTRETVYRYERGEIEAPLKIAEKLINMFGEDITKKIKINETPKVSQEELASRQIGAKTYRLLESHPDAIKWEDRTILISSNAERYQKTVELANALGAEVERA
What are the official names of this protein?
Putative HTH-type transcriptional regulatory protein PAE1627.
Protein: NTPTH_METJA
Sequence: MRIFITGMPGVGKTTLALKIAEKLKELGYKVGGFITKEIRDGGKRVGFKIITLDTNEETILAYVGDGKIKVGKYAVFIENLDNVGVEAIKRALKDADIIIIDELGAMEFKSRKFSEVVDEVIKSDKPLLATLHRNWVNKFKDKGELYTLTIENREKLFEEILNKILAGLK
What is the function of this protein?
Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP.  May hydrolyze nucleoside diphosphates with lower efficiency (By similarity).
What are the official names of this protein?
Nucleoside-triphosphatase THEP1, NTPase THEP1, Nucleoside triphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the THEP1 NTPase family.
Protein: TARG1_MOUSE
Sequence: MANPAQPPLQDPGSTSPLELPEMEKLLTKVENKDDQALNLSKSLSGALDLEQNGHSLPFKVISEGHRQPSLSGSPSRVSSRRASSVITTSYAQDQEAPKDYLVLAIASCFCPVWPLNLIPLIFSIMSRSSVQQGDLDGARRLGRLARLLSITFIILGIVIIIVAVTVNFTVPK
What is the function of this protein?
Regulates insulin-mediated adipose tissue glucose uptake and transport by modulation of SLC2A4 recycling.  Not required for SLC2A4 membrane fusion upon an initial stimulus, but rather is necessary for proper protein recycling during prolonged insulin stimulation.
What are the official names of this protein?
Trafficking regulator of GLUT4 1, Dispanin subfamily B member 1, DSPB1, Tumor suppressor candidate 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Cytoplasm, perinuclear region. Note=Shifts from low-density microsome vesicles to the cell membrane upon insulin stimulation.
Protein: RPOB_AZOVD
Sequence: MAYSYTEKKRIRKDFSKLPDVMDVPYLLAIQLDSYREFLQAGVSKDKLRDVGLHAAFKSVFPIISYSGNAALEYVGYRLGEPAFDVKECVLRGVTFAVPLRVKVRLIIFDKESSNKAIKDIKEQEVYMGEIPLMTENGTFIVNGTERVIVSQLHRSPGVFFDHDRGKTHSSGKLLYSARIIPYRGSWLDFEFDPKDAVFVRIDRRRKLPASVLLRALGYSTEEVLDIFYDTNVFHVTEQGLSLELVPQRLRGEIAVFDIKDASGKVIVEQGRRITARHINQLEKAGIKELDVPLEYVLGRTSAKVIVHPSTGEIIAECNSELTQDLLVKIAKAQVVRIETLYTNDIDCGPFISDTLKIDSTTNQLEALVEIYRMMRPGEPPTKDAAETLFNNLFFSAERYDLSAVGRMKFNRRIGREEIEGAGVLSREDIVDVLKTLVDIRNGKGIVDDIDHLGNRRVRCVGEMAENQFRVGLVRVERAVKERLSMAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLAAYARTNQYGFLESPYRVVKEGQVTDEIVFLSAIEEADHVIAQASATLDENGRLIDELVAVRHLNEFTVKAPEDVTLMDVSPRQVVSVAASLIPFLEHDDANRALMGSNMQRQAVPTLRADKPLVGTGMERNVARDSGVCVVARRGGVIDSVDASRIVVRVNNDEVETGEAGVDIYNLTKYTRSNQNTCINQRPLVSKGDQVARGDIMADGPSTDMGELALGQNMRVAFMPWNGFNFEDSICLSERVVQEDRFTTIHIQELTCVARDTKLGPEEITADIPNVGEAALNKLDEAGIVYVGAEVMAGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPTGTKGTVIDVQVFTRDGVERDSRALAIERMQLDEIRKDLNEEFRIVEGATFERLRAALVGAVCEGGAGLKKGTEIDDGILDGLERGQWFKLRMADDALNEQLEKAQAYLADRRQLLDDKFEDKKRKLQQGDDLAPGVLKIVKVYLAIKRRIQPGDKMAGRHGNKGVVSVIMPVEDMPYDANGTPVDIVLNPLGVPSRMNVGQILETHLGLAAKGLGEKINRMLEEQRKVAELRQFLGEVYNEIGGRQKEDLDSLSDSEILDLASNLRGGVPMATPVFDGARETEIKAMLKLADLPESGQMRLFDGRTGNQFERPTTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEAGMPESFNVLIKEIRSLGIDIELETE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: R12BA_MOUSE
Sequence: MAVVIRLLGLPFIAGPVDIRHFFKGLTIPDGGVHIIGGKVGEAFIIFATDEDARRAISRSGGFIKDSSVELFLSSKVEMQKTIEMKRTARVGRGRPGSGASGVGNVYHFSDALKEEESYSGYGSSVNRDAGFHTNGTGLDLRPRKTRPLKAENPYLFLRGLPYLVNEDDVRVFFSGLCVDGVILLKHHDGRNNGDAIVKFASCVDASGGLKCHRSFMGSRFIEVMQGSEQQWIEFGGTATEGGDTPRMRSEEHSPSRRINGRHFRKRSHSKSPRARSRSPLGFYVHLKNLSLNTNKRDLRNLFRDTDLTNDQIKFVYKDERRTRYAFVMFKNQKDYNTALGLHKTVLQYRPVLIDPVSRKEMVRIIECYEKKRPESLEKERPGRVSQKYSQEGFSGSGQKLCIYIRNLPFDVTKGEVQKFFADFSLVEDDIYLLCDDKGVGLGEALVRFKSEEQAMKAERLNRQRFLGIEVLLRLISEEQMQEFGVKSSWLSNERTQACSRSHDGDDCSCLFDLKDPSSCSFGQSESLRYHPKDLRKMGHFKHPQGYFRQSDRRSPEDFRHSPEDYRHPWEEHTSHSREEDWRLPLEDWKWSQEDDFRQCHEKDRRQLRSPWEEDFRRPSQEHFRRSYQEHIRQPPEEHFRRSREEDFRHVADEDFRQASDEDFRTSQEDLRYPTDEDFRRVSVEDLREVPEKDLRLPKNFRSPGEEFWTPPDFRGQHPFGNFDHLQGGKFDFEKYKFGSFPDAKVTSDLNLNCVSDKIIPVKISNLPFKANASEILDFFHGYKVIPDSVSLQYNEQGLPIGEAIVAMTNYNEALAAVKDLSGRPVGPRKVKLSLL
What are the official names of this protein?
RNA-binding protein 12B-A, RNA-binding motif protein 12B-A.
Protein: RS19_MESH7
Sequence: MARSLKKGPFADDHLLKKVDEAIAKNSRKPIKTWSRRSTIFPQFVGLTFLVHNGKIFNEVYVTDDMVGHKLGEFSPTRTYHGHGKDKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ILVC_SALA4
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQFEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFIAELQPGDLGSAIPEGAVDNAQLRDVNDAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PGK_DICTD
Sequence: MAKKTILDLRDEDLKGKRVLVRVDFNVPLKNGVITDDRRIREALPTIKYLMDKGAKVILVSHLGRPKGFQDDLRLDPVAKRLSELLGKPVKKLNDCIGEEVEREISNMKEGDVILLENIRFYKEEEANDPEFAKKLASLADLYVNDAFGTAHRAHASTAGVAQYIPGVAGLLMKKEIEIMGKALESPERPFICILGGAKVSDKIGVIKNLMNKVDGFLIGGGMMFTFLKALGYEIGKSIVEEDKLDLAREIMNMAKERGIQFLLPKDAVVVKEIKEDAPTSIKDIDKFEKDDIGVDIGPKTIELFREEILKAKTIIWNGPMGIFEIPAFANGTRKIAEAIAENRNCVSIVGGGDSAAAIQTLGLEDKFTHISTGGGASLEFLEGKELPGVAVLQDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNX3_YEAST
Sequence: MPREFKSFGSTEKSLLSKGHGEPSYSEIYAEPENFLEIEVHNPKTHIPNGMDSKGMFTDYEIICRTNLPSFHKRVSKVRRRYSDFEFFRKCLIKEISMLNHPKVMVPHLPGKILLSNRFSNEVIEERRQGLNTWMQSVAGHPLLQSGSKVLVRFIEAEKFVG
What is the function of this protein?
Required for retention of late Golgi membrane proteins.  Component of the retrieval machinery that functions by direct interaction with the cytosolic tails of certain TGN membrane proteins during the sorting/budding process at the prevacuolar compartment.  Binds phosphatidylinositol 3-phosphate (PtdIns(P3)).
What are the official names of this protein?
Sorting nexin-3, Golgi retention deficient protein 19.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Prevacuolar compartment membrane; Peripheral membrane protein; Cytoplasmic side. Note=Mainly cytoplasmic. A minor amount associates with membranes.
Protein: CYSK_STAAC
Sequence: MAQKPVDNITQIIGGTPVVKLRNVVDDNAADVYVKLEYQNPGGSVKDRIALAMIEKAEREGKIKPGDTIVEPTSGNTGIGLAFVCAAKGYKAVFTMPETMSQERRNLLKAYGAELVLTPGSEAMKGAIKKAKELKEEHGYFEPQQFENPANPEVHELTTGPELLQQFEGKTIDAFLAGVGTGGTLSGVGKVLKKEYPNIEIVAIEPEASPVLSGGEPGPHKLQGLGAGFIPGTLNTEIYDSIIKVGNDTAMEMSRRVAKEEGILAGISSGAAIYAAIQKAKELGKGKTVVTVLPSNGERYLSTPLYSFDD
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: TRPB_LISMH
Sequence: MTYQAPDENGFYGKFGGRFVPETLMKAVKELDEAYRASKTDPAFQKELNYYLKEYVGRETPLYFAEQLTAHAGGAKIYLKREDLNHTGAHKINNTIGQALLARQMGKQKVVAETGAGQHGVATATVAALFNMECTIFMGEEDVKRQSLNVFRMELLGAKVVSVKAGSRTLKDAVNEALRFWVANVEDTHYIMGSVLGPHPFPEIVRDYQSVIGIEARKQHLEKEGKLPDAIVACVGGGSNAMGLFYPFVDDVSVQMHGVEAAGHGLETEFHAATISKGEIGILHGAMMDVLQDENGQILEAFSISAGLDYPGIGPEHSFFRDLGRAAYHSVTDDEAVEAFQLLCRTEGIIPALESSHAISYAVKLASQMRPEESMVVCLSGRGDKDVNQLKERLEGQTND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: OGR1_HUMAN
Sequence: MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCSRTGRAREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNSPGSGGFPTGRLA
What is the function of this protein?
Proton-sensing receptor involved in pH homeostasis.  May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone.  Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization.  The receptor is almost silent at pH 7. 8 but fully activated at pH 6. 8.  Also functions as a metastasis suppressor gene in prostate cancer (By similarity).
What are the official names of this protein?
Ovarian cancer G-protein coupled receptor 1, OGR-1, G-protein coupled receptor 68, GPR12A, Sphingosylphosphorylcholine receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH2_VIBC3
Sequence: MAKKPSIELPPFEIPAGYALIAGVDEVGRGPLVGDVVTAAVILDPNRPIMGLNDSKKLSEKKRLALFPEIQVKALAWAVGRCSPQEIDELNIFQATMVAMQRAVAGLRIQPDLVLIDGNKIPKLPMEAQAVVKGDLRVAQISAASIIAKVIRDQEMEALDKQYPQFGFAKHKGYPTAAHFAAIEQHGVIEQHRKSFGPVKRALGIE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_NITSB
Sequence: MIRHLITTKDFTKDEIEDLFDDAQKFLNEPTPHLLKNKLIITIFFENSTRTRSSFEVAAKRLGAEVVSLDVSKSSTKKGETLFDTAANLNAMEPHAIVVRHKSAGVPYILSKYVSCSLINGGDGAHAHPTQALLDLFTLKQHFKAVEGKKIAIVGDIKNSRVANSNIELLQRFGMKVILVAPPHFLPKTDLPISYDLHAIINEVDAIMSLRTQTERHKYPIYASLRDYGNDFCITKDLIKDKDLIILHPGPVHRNIDISDEVLTDPRCKVLEQVKNGVAVRMAVLKKLIMHG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: RS18_WOLPM
Sequence: MMKRRNSFNNSYVSVNNRTGFRRSKVCPLAASKDEDIDYKNIDLLSKFTSDYGRILPRRLTGVCAKKQRKLRLAIIRARFLALIPYCTKKV
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: NKX61_HUMAN
Sequence: MLAVGAMEGTRQSAFLLSSPPLAALHSMAEMKTPLYPAAYPPLPAGPPSSSSSSSSSSSPSPPLGTHNPGGLKPPATGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQGSILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHAAEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGLLLHASEPESSS
What is the function of this protein?
Transcription factor which binds to specific A/T-rich DNA sequences in the promoter regions of a number of genes.  Involved in the development of insulin-producing beta cells in the islets of Langerhans at the secondary transition (By similarity).  Together with NKX2-2 and IRX3 acts to restrict the generation of motor neurons to the appropriate region of the neural tube.  Belongs to the class II proteins of neuronal progenitor factors, which are induced by SHH signals (By similarity).
What are the official names of this protein?
Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGB_BURCJ
Sequence: MSEPIDLSQIAPTLKAEILAEALPYIRRYHGKSVVIKYGGNAMTEERLKQGFARDVILLKLVGINPVIVHGGGPQIDHALKKIGKAGTFIQGMRVTDEETMEVVEWVLGGEVQQDIVMLINHFGGHAVGLTGKDGGLIHARKLLMPDRDNPGQYIDIGQVGEVEAINPAVVKALQDDAFIPVISPIGFGEDGLSYNINADLVAGKLATVLNAEKLLMMTNIPGVMDKDGNLLTDLSAREIDALFEDGTISGGMLPKISSALDAAKSGVKSVHIVDGRIEHSVLLEILTEQPFGTMIRSH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOBA_BURO0
Sequence: MPAPASPSIAGLLLAGGRATRMDGVDKGLQLLDGTPLALHVLRRLAPQVDETLISANRHADRYAELGAPFDARIIADETPDFPGPLAGLLAGMRAARAPLVACSPCDTPYLPVDLVARLRAALDAQQAAIAMAVTVDAQQVRSPQPTFALLRTSLADDLAARLAAGDRKVRAWYARHKTVEVEFRDERAFYNANSWQELAALARR
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
Protein: LIPA_ENT38
Sequence: MSKPIVMERGVKYRDADKMALIPVKNVVTEREALLRKPEWMKIKLPADSSRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPLKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCISAIREKSPSIKIETLVPDFRGRMDRALEILTATPPDVFNHNLENVPRVYRQVRPGADYNWSLKLLERFKEAHPHIPTKSGLMVGLGETNAEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEAMAMGFTHAACGPFVRSSYHADMQAKGEEVK
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPR_RAT
Sequence: MPVKRSLKLDDQFEENSFGPSKIMRKKSITAFSPTTGTYQLSPFSSPRTPKEQEHRDGPSNGTRKWSVLSSPARQDSTVKGSDGFMMLLSKIERSSEKTMEIMKNLSSLQALEGNRQLEDLLGVSLVPCSLKSEAKKTKELMTKVMKQKLFEKKNSRIPPKEHHPNSFEFLKAILN
What is the function of this protein?
Transcription coregulator that can have both coactivator and corepressor functions.  Involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion.  In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid.  Acts as a coactivator for estrogen receptor alpha.  Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1.  Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases.  May also act as an inhibitor of cyclin A-associated kinase.  Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex (By similarity).
What are the official names of this protein?
Centromere protein R, CENP-R, Nuclear receptor-interacting factor 3.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore.
Protein: MOBA_ACIFR
Sequence: MIALSQEAVRSKDTINHYVLSWREGEQPSPEQVEEAVSIFMDELGVKDHQAIYGLHADTDNLHLHLAINRVHPETLKVVKINNGFDIEAAHKAIARIENAQGWQREQNGRYQVLENGELGREHIDKDKPRQPAQPKRDMENRTGEKSAERIAIEDGAPIIKKAQTWEQLHRELAAKGMRYEKTGSGATLFVGDVGVKASSADRDASLSKLQKRLGAYQPPQRQQVAQREPEPIKPDVPGWKDYITGRKAHYSEKNADKLVQDKRQEQERKQLAEQQKARRDELMRGNWKGKGEVLNAMRSVIAAEQAAEKAALKEKHQKQREQHRQQFRPYPDLEQWQRMQKSPELAEQWRHRASEPQRIEGDRSEPPTPRDIRAYQPEIVGQQVHYSRKEEGGRGGGVSFVDKGKSID
What are the official names of this protein?
Protein MobA.
Protein: CLPX_METS4
Sequence: MSKAGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHAAKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLERIISARGKGTSIGFGATVQAPDDRRTGEIFRAVEPEDLLKFGLIPEFVGRLPVLATLEDLDETALKRILQEPKNALVKQYQRLFEMENVDLTFQEEALTLVARKAIERKTGARGLRSILESILLETMYDLPGLDSVEQVVIGPEVVEGKARPLYIHGDRAKDAPASVSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PDUH_SALTY
Sequence: MDSNHSAPAIVITVINDCASLWHEVLLGIEEEGIPFLLQHHPAGDIVDSAWQAARSSPLLVGIACDRHSLVVHYKNLPASAPLFTLMHHQDSQAQRNTGNNAARLVKGIPFRDLHA
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Propanediol dehydratase-reactivating factor small subunit, DDR small subunit, Propanediol utilization protein PduH.
What is the protein family that this protein belongs to?
Belongs to the DdrB/PduH family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: PUR7_SALG2
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNHFIMTKLAEAGIPTQMERLLSDTECLVKKLEMVPVECVVRNRAAGSLVKRLGVEEGMELNPPIFDLFLKNDALHDPMVNSSYCETFGWVSQENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLDKMDKDRFRQSLGGLIEAYEAVAHRLGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: RL25_PECCP
Sequence: MITIKAEVRKDQGKGASRRLRSAGKFPAIVYGGSEAPVSIELDHDSVKNQEAKEGFYGTALILSIDGKEVQVKVQAVQRHVYKPKLTHIDFVRV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.