PharMolix/UniProtQA huggingface dataset:
Protein: HLY2_VIBPA
Sequence: MKYRYFAKKSFLFISMLAAFKTFAFELPSVPFPAPGSDEILFVVRDTTFNTNAPVNVEVSDFWTNRNVKRKPYKDVYGQSVFTTSGTKWLTSYMTVNINDKDYTMAAVSGYKHGHSAVFVKSDQVQLQHSYDSVANFVGEDEDSIPSKMYLDETPEYFVNVEAYESGSGNILVMCISNKESFFECKHQQ
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.
What are the official names of this protein?
Thermostable direct hemolysin 2, Kanagawa phenomenon-associated hemolysin.
What is the protein family that this protein belongs to?
Belongs to the TDH hemolysin family.
Protein: Y334_METJA
Sequence: MSKMGLFKKEKDNGVIDDLVPKKSDYVEKIAQEAIRKDKVDALVRKHEMEQFYHEVSQNEKIAELKAELAKKEKEIEELKEEIRGLKGKAGGLGIGGSQVTR
What are the official names of this protein?
Uncharacterized protein MJ0334.
Protein: PUR7_SPHAL
Sequence: MARRRQIYEGKAKILYEGPEPGTLIQYFKDDATAFNAQKRGTINGKGVLNNRISEHVFTLLGNIGVPTHFIRRLNMREQLIRQVEIVPIEVIVRNVAAGTLSKRLGIEEGTQLPRTLIEYCYKDDALGDPLVAEEHIACFNWCSQDELHDIQDMAIRINDFMSGMFAAVGIRLVDFKLEFGRLYEGDFSRIILADEISPDGCRLWDMTTNEKLDKDRFRRDLGGEVEAYQEVARRLGLLPEGGDNAVLDLESHRKKKG
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: BGLG_ASPTN
Sequence: MANIAHLIVSGLLAATVAHGQQYEGSSRSEDAFSYVQPRNTTILGQYGHSPAVLPSPNSTGSGGWQAAHTKARHFVSQLTLEEKADMVTGQPGPCVGNIVAIPRLGFNGLCLQDGPLAIRVADYASVFSAGVTAASTWDRDVLYERAFAMGQEFRAKGAHIALGPVAGPLGRSAYGGRNWEGFAADPYLTGVAMELSVKGYHDAGVQATPKHFIGNEQETQRNPIYNPNGTITDVLQEAVSSNIDDRTMHELYLWPFANAAHAKAAAFMCSYQRLNGSYACQNSKALNGLLKEELGFQGYVMSDWGGTHSGVASIESGLDMNMPGGLGPYGTIPQAGSFYGGNVTQGVKNGTIDEARVDDMIIRIMTPYYWLGQDKDFPSVDPSSADLNTFSPRSTWLRQFNLTGERNRDVRGDHAKIIRRQAAEATVLLKNEKNALPLKSPKSLAIFGNDAGEPTMGAVNQANFEFGTLAAGGGSGTGRFTYVVSPLEAIQSRAKQANTLVQYWMNNTDIATTDVTTLWVPAPPDACLVFLKTWAEEGEDREYLHVDYDGNDVVSSVASKCNNTIVVTHSSGINELPFADHPNVTAILAAHYPGQESGNSIVDVLYGDVNPSGRLPYTIARNGSEYNAPPTTEVTTTGAEDWQAWFNEKLEIDYRYFDAHNISVLYEFGFGLSYTTFNLSEINAEPLVESISSVPEQRPIQPGGNPALWENVYNVSVVVTNTGDVEGKAVPQLYVTFPDSTPAGTPPKQLRGFDKVALKPGQSQAASFQLMRRDLSYWDVVSQQWLIPEGEFVISVGFSSRDLREVVRVTPVSGST
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase G, Beta-D-glucoside glucohydrolase G, Cellobiase G, Gentiobiase G.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MMAA3_MYCTU
Sequence: MSDNSTGTTKSRSNVDDVQAHYDLSDAFFALFQDPTRTYSCAYFERDDMTLHEAQVAKLDLTLGKLGLEPGMTLLDVGCGWGSVMKRAVERYDVNVVGLTLSKNQHAYCQQVLDKVDTNRSHRVLLSDWANFSEPVDRIVTIEAIEHFGFERYDDFFKFAYNAMPADGVMLLHSITGLHVKQVIERGIPLTMEMAKFIRFIVTDIFPGGRLPTIETIEEHVTKAGFTITDIQSLQPHFARTLDLWAEALQAHKDEAIEIQSAEVYERYMKYLTGCAKAFRMGYIDCNQFTLAK
What is the function of this protein?
Involved in the biosynthesis of methoxymycolic acid.  It catalyzes the O-methylation of the hydroxy group of the hydroxymycolate to form a methyl ether.
What are the official names of this protein?
Methoxy mycolic acid synthase MmaA3, Mycolic acid methyltransferase, MA-MT, S-adenosylmethionine-dependent methyltransferase, AdoMet-MT, SAM-MT.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
Protein: HIGB1_MYCTU
Sequence: MPPPDPAAMGTWKFFRASVDGRPVFKKEFDKLPDQARAALIVLMQRYLVGDLAAGSIKPIRGDILELRWHEANNHFRVLFFRWGQHPVALTAFYKNQQKTPKTKIETALDRQKIWKRAFGDTPPI
What is the function of this protein?
Toxic component of an atypical, type II toxin-antitoxin chaperone (TAC) system.  Upon expression in M. smegmatis inhibits colony formation and cell growth (PubMed:20011113, PubMed:23927792).  Ectopic expression in wild-type M. tuberculosis has no effect on cell growth; ectopic expression in a triple higB1-higA1-Rv1957 (delta TAC) disruption mutant causes growth arrest, killing a considerable proportion of the cells.  Increased ectopic expression leads to decreased levels of IdeR- and Zur-regulated genes as well as cleavage within the mRNA region of tmRNA (transfer-mRNA), strongly suggesting it is an endoribonuclease; also degrades E. coli and M-smegmatis tmRNA (PubMed:23927792).  Its toxic effect is neutralized by coexpression with antitoxin HigA.  Neutralization of HigB1 toxin in E. coli or M. marinum also requires SecB-like chaperone Rv1957, making this the first toxin-antitoxin chaperone (TAC) system (PubMed:21536872).
What are the official names of this protein?
Probable endoribonuclease HigB1, Toxin HigB1.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial HigB family.
Protein: METK_ECO55
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLA_CERS1
Sequence: MTDFFAGIPQIRYEGEGSSNEFAFRHYNPDEVILGKRMEEHLRFAVAWWHSFAWPGGDPFGGQTFNRPWFGDTLDLAKLKADVAFEMFDILGAPFFCFHDADIRPEGATFAESKRNLEEIVDHIGTRMEGSKTKLLWGTANLFSHRRFMSGAATNPDPDVFAWSAATVKGCMDATMKLGGANYVLWGGREGYETLLNTDLTREAENAGRFLQMVVDYKHKIGFQGTILIEPKPQEPSKHQYDYDVATVYGFLKRFGLEKEVKLNIEQGHAILAGHSFEHELALAASLGILGSIDMNRNDYQSGWDTDQFPHNHPEMALAYYEILRAGGFTTGGTNFDAKIRRQSLDPEDLVLAHVGGMDTCARALKAAARLYEDGSLEAARAARYAGWETPEAQAMLASSLEEIEARVLAEGINPEPRSGRQERLENLWNRFV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_LEGPH
Sequence: MATINQLVRKPRVDVKKKSNVPALESCPQRRGVCTRVYTTTPKKPNSAMRKVARVRLTNGFEVTSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVNDRKQGRSKYGTKKPKDKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RL15_MYXXD
Sequence: MSTLNKLQRPARSWHRKKRVGRGQGSGLGKTAGRGGKGQKARTGNMRFEGFEGGQSPLQRRLPKFGFTPPNRTVYAVVNLSDLEQHFDAGATADVETLRKVGLVKGRYHGVKLLARGELTKKVTVVVHKASEAAKAAIQKAGGAVEEIPLVAHKPESAAKAHAGKGVKAPRQPKA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: IRPL1_PONPY
Sequence: MKAPIPHLILLYATFTQSLKVVTKRGSADGCTDWSIDIKKYQVLVGEPVRIKCALFYGYIRTNYSLAQSAGLSLMWYKSSGPGDFEEPIAFDGSRMSKEEDSIWFRPTLLQDSGLYACVIRNSTYCMKVSISLTVGENDTGLCYNSKMKYFEKAELSKSKEISCRDIEDFLLPTREPEILWYKECRTKTWRPSIVFKRDTLLIREVREDDIGNYTCELKYGGFVVRRTTELTVTAPLTDKPPKLLYPVESKLTIQETQLGDSANLTCRAFFGYSGDVSPLIYWMKGEKFIEDLDENRVWESDIRILKEHLGEQEVSISLIVDSVEEGDLGNYSCYVENGNGRRHASVLLHKRELMYTVELAGGLGAILLLLVCLVTIYKCYKIEIMLFYRNHFGAEELDGDNKDYDAYLSYTKVDPDQWNQETGEEERFALEILPDMLEKHYGYKLFIPDRDLIPTGTYIEDVARCVDQSKRLIIVMTPNYVVRRGWSIFELETRLRNMLVTGEIKVILIECSELRGIMNYQEVEALKHTIKLLTVIKWHGPKCNKLNSKFWKRLQYEMPFKRIEPITHEQALDVSEQGPFGELQTVSAISMAAATSTALATAHPDLRSTFHNTYHSQMRQKHYYRSYEYDVPPTGTLPLTSIGNQHTYCNIPMTLINGQRPQTKSSREQNPDEAHTNSAILPLLPRETSISSVIW
What is the function of this protein?
May regulate secretion and presynaptic differentiation through inhibition of the activity of N-type voltage-gated calcium channel.  May activate the MAP kinase JNK (By similarity).  Plays a role in neurite outgrowth (By similarity).  During dendritic spine formation can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD (By similarity).
What are the official names of this protein?
Interleukin-1 receptor accessory protein-like 1, IL-1-RAPL-1, IL-1RAPL-1, IL1RAPL-1, X-linked interleukin-1 receptor accessory protein-like 1.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cytoplasm. Cell projection, axon. Cell projection, dendrite. Note=May localize to the cell body and growth cones of dendrite-like processes.
Protein: ILVC_ECOL5
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LPF2_ECOL6
Sequence: MNAAIFRFFFYFST
What are the official names of this protein?
Phenylalanyl--tRNA ligase operon leader peptide, pheST attenuator peptide.
Protein: HIPK1_MOUSE
Sequence: MASQLQVFSPPSVSSSAFCSAKKLKIEPSGWDVSGQSSNDKYYTHSKTLPATQGQASSSHQVANFNLPAYDQGLLLPAPAVEHIVVTAADSSGSAATATFQSSQTLTHRSNVSLLEPYQKCGLKRKSEEVESNGSVQIIEEHPPLMLQNRTVVGAAATTTTVTTKSSSSSGEGDYQLVQHEILCSMTNSYEVLEFLGRGTFGQVAKCWKRSTKEIVAIKILKNHPSYARQGQIEVSILSRLSSENADEYNFVRSYECFQHKNHTCLVFEMLEQNLYDFLKQNKFSPLPLKYIRPILQQVATALMKLKSLGLIHADLKPENIMLVDPVRQPYRVKVIDFGSASHVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQTQGLPAEYLLSAGTKTTRFFNRDPNLGYPLWRLKTPEEHELETGIKSKEARKYIFNCLDDMAQVNMSTDLEGTDMLAEKADRREYIDLLKKMLTIDADKRITPLKTLNHQFVTMSHLLDFPHSSHVKSCFQNMEICKRRVHMYDTVSQIKSPFTTHVAPNTSTNLTMSFSNQLNTVHNQASVLASSSTAAAATLSLANSDVSLLNYQSALYPSSAAPVPGVAQQGVSLQPGTTQICTQTDPFQQTFIVCPPAFQTGLQATTKHSGFPVRMDNAVPIVPQAPAAQPLQIQSGVLTQGSCTPLMVATLHPQVATITPQYAVPFTLSCAAGRPALVEQTAAVLQAWPGGTQQILLPSAWQQLPGVALHNSVQPAAVIPEAMGSSQQLADWRNAHSHGNQYSTIMQQPSLLTNHVTLATAQPLNVGVAHVVRQQQSSSLPSKKNKQSAPVSSKSSLEVLPSQVYSLVGSSPLRTTSSYNSLVPVQDQHQPIIIPDTPSPPVSVITIRSDTDEEEDNKYKPNSSSLKARSNVISYVTVNDSPDSDSSLSSPHPTDTLSALRGNSGTLLEGPGRPAADGIGTRTIIVPPLKTQLGDCTVATQASGLLSSKTKPVASVSGQSSGCCITPTGYRAQRGGASAVQPLNLSQNQQSSSASTSQERSSNPAPRRQQAFVAPLSQAPYAFQHGSPLHSTGHPHLAPAPAHLPSQPHLYTYAAPTSAAALGSTSSIAHLFSPQGSSRHAAAYTTHPSTLVHQVPVSVGPSLLTSASVAPAQYQHQFATQSYIGSSRGSTIYTGYPLSPTKISQYSYL
What is the function of this protein?
Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis.  Plays a role as a corepressor for homeodomain transcription factors.  Phosphorylates DAXX and MYB.  Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm.  Inactivates MYB transcription factor activity by phosphorylation.  Prevents MAP3K5-JNK activation in the absence of TNF.  TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis.  May be involved in anti-oxidative stress responses.  Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis.  Promotes angiogenesis and to be involved in erythroid differentiation.  May be involved in malignant squamous cell tumor formation.  Phosphorylates PAGE4 at 'Thr-51' which is critical for the ability of PAGE4 to potentiate the transcriptional activator activity of JUN (By similarity).
What are the official names of this protein?
Homeodomain-interacting protein kinase 1, Nuclear body-associated kinase 2, Protein kinase Myak.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus speckle. Note=Predominantly nuclear. Translocates from nucleus to cytoplasm in response to stress stimuli via SENP1- mediated desumoylation.
Protein: RSMA_AFIC5
Sequence: MSQIDDLPPLREVIRKYDLFARKSLGQNFLFDLNLTARIARAAGPLDDVTVIEIGPGPGGLTRALLATGAKRVIAVERDERAIPALEEIARRYPGRLEIIHGDATTFDPTPLLQGERARIVANLPYNIATLLLTGWLSVEPWPPWFDMMVLMFQREVAERIVATENDEAYGRLGVLANWRAETKILFDIAPGAFVPPPKVMSSVVRLAPRAAPLACSRRALEQVTAAAFNQRRKMLRQSLKALGVDPAALAEAAGVDPTRRAETVSIAGFVAMANRLIELKA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VDE_TOBAC
Sequence: MALAPHSNFLANHETIKYYVGSKLPGHKRFSWGWEDYFGSIVVAKICSSRRIPRYFRKSPRICCGLDSRGLQLFSHGKHNLSPAHSINQNVPKGNSGCKFPKDVALMVWEKWGQFAKTAIVAIFILSVASKADAVDALKTCTCLLKECRLELAKCISNPACAANVACLQTCNNRPDETECQIKCGDLFENSVVDEFNECAVSRKKCVPRKSDVGDFPVPDPSVLVQKFDMKDFSGKWFITRGLNPTFDAFDCQLHEFHTEENKLVGNLSWRIRTPDGGFFTRSAVQKFVQDPKYPGILYNHDNEYLLYQDDWYILSSKVENSPEDYIFVYYKGRNDAWDGYGGSVLYTRSAVLPESIIPELQTAAQKVGRDFNTFIKTDNTCGPEPPLVERLEKKVEEGERTIIKEVEEIEEEVEKVRDKEVTLFSKLFEGFKELQRDEENFLRELSKEEMDVLDGLKMEATEVEKLFGRALPIRKLR
What is the function of this protein?
Part of the xanthophyll (or violaxanthin) cycle for controlling the concentration of zeaxanthin in chloroplasts.  Catalyzes the two-step mono de-epoxidation reaction.  Stereospecific for all-trans xanthophylls.  Zeaxanthin induces the dissipation of excitation energy in the chlorophyll of the light-harvesting protein complex of photosystem II.
What are the official names of this protein?
Violaxanthin de-epoxidase, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Lumenal side.
Protein: DRE2H_ARATH
Sequence: MPRKRKSRGTRDVAEILRKWREYNEQTEADSCIDGGGSKPIRKAPPKRSRKGCMKGKGGPENGICDYTGVRQRTWGKWVAEIREPGRGAKLWLGTFSSSYEAALAYDEASKAIYGQSARLNLPLLPLCQARLLHFLMNLKFVHVRIQMQDLVLVRSD
What is the function of this protein?
Putative transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'.
What are the official names of this protein?
Putative dehydration-responsive element-binding protein 2H, Protein DREB2H.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: G6PT2_HUMAN
Sequence: MARLPAGIRFIISFSRDQWYRAFIFILTFLLYASFHLSRKPISIVKGELHKYCTAWDEADVRFSSQNRKSGSAAPHQLPDNETDCGWAPFDKNNYQQLLGALDYSFLCAYAVGMYLSGIIGERLPIRYYLTFGMLASGAFTALFGLGYFYNIHSFGFYVVTQVINGLVQTTGWPSVVTCLGNWFGKGRRGLIMGVWNSHTSVGNILGSLIAGYWVSTCWGLSFVVPGAIVAAMGIVCFLFLIEHPNDVRCSSTLVTHSKGYENGTNRLRLQKQILKSEKNKPLDPEMQCLLLSDGKGSIHPNHVVILPGDGGSGTAAISFTGALKIPGVIEFSLCLLFAKLVSYTFLFWLPLYITNVDHLDAKKAGELSTLFDVGGIFGGILAGVISDRLEKRASTCGLMLLLAAPTLYIFSTVSKMGLEATIAMLLLSGALVSGPYTLITTAVSADLGTHKSLKGNAHALSTVTAIIDGTGSVGAALGPLLAGLLSPSGWSNVFYMLMFADACALLFLIRLIHKELSCPGSATGDQVPFKEQ
What is the function of this protein?
Inorganic phosphate and glucose-6-phosphate antiporter.  May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction.  Independent of a lumenal glucose-6-phosphatase.  May not play a role in homeostatic regulation of blood glucose levels.
What are the official names of this protein?
Glucose-6-phosphate exchanger SLC37A1, Glycerol-3-phosphate permease, G-3-P permease, Solute carrier family 37 member 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HIS8_YERPA
Sequence: MSQSNNVTDLARANIRALTPYMSARRLGGNGDVWLNANEYPLGTEYQLTTQTFNRYPECQPKHVIERYAAYAGLPPEQVLVSRGADEGIELLIRAFCEPGQDAILFCPPTYGMYAVSAETFGVERRTVPAQADWQLDLPAIANNLEQVKVIYVCSPNNPTGNLINPADLQAVLALAQGRAIVAIDEAYIEFCPQASVSNWLKDYPNLVILRTLSKAFALAGLRCGFTLANSDIIQLLLKVIAPYPLSTPVADIAAQALSPKGIEQMRQRVSEVRANRAWLQSALQDCACVEQVFTSESNYLLARFTASSSVFNALWDQGIILRDQNKQPGLANCLRITIGTRQECERVIAALAPLPGIDNSNNIDNQNKTYSQTSSIRKGTI
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: HSLU_GEOKA
Sequence: MMAETLTPRQIVEKLDQFIVGQKEAKKAVAIALRNRYRRSLLDEKLRDEVMPKNILMIGPTGVGKTEIARRLAKLVGAPFIKVEATKFTEVGYVGRDVESMVRDLVETSVRLVKERKMNEVKDRAEQQANKRLVELLVPGKPKQTIKNPLELLFGGQGAQADNSYSHEDEQVEQKRRQVAWQLANGQLENEMVTIEIEEQTPLWFDFLQGAGIEQMGMNMQDALSSLMPKRRKKRRLKVSEARKVLINEEAQKLIDMDEVTQEAVRLAEQSGIIFIDEIDKIARSGAVSGSADVSREGVQRDILPIVEGSTVMTKYGPVKTDHILFIAAGAFHMAKPSDLIPELQGRFPIRVELAKLSVDDFVRILVEPNNALIKQYQALLATEGISLEFSDDAIRKIAEVAFEVNQTTDNIGARRLHTILEKLLEDLLFEAPDIGIDKVVITPQYVEQKLGSIVKNKDLSEFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGRA_STAES
Sequence: MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDPVGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIMFFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI
What is the function of this protein?
Required for high-level post-exponential phase expression of a series of secreted proteins.
What are the official names of this protein?
Accessory gene regulator protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPTB_EMENI
Sequence: MATDGMVLHKRSLSEGGTSTQAWKVLSQTLPSRGPDVDAWWQLTGRHLAVLLDAAAYPIEKQYECLLYHYHYAAPYLGPAPREGASPPTWKSMLQLDGTPFEFSWKWNNPGGEPDVRFGLEPIGPMAGTSLDPLNHLAMREILYKLSSAVPGSDLTWTHHFLATLFDHDYAKYTQKAATMGSSIGTSLVYSLEFQRKSTGLKTYFHPRKLDQQAFLDIPSWEASFRGLHPNSPSRTAVHEFLSTNPEGKLLKPFCLSVDNCSPAKARIKWYFNSPHTNFRAIREIMTLGGRIADTETRTKQFSELFNLLKTVTEEHADFPETSEFPYVPNNGDSIIPNFADAPDMLKGCVYFFDIAPGRNLPAIKVYFPVRNHCRNDLAVTQNLNRWLESRGRGQYGAAFGRALETIADYRRLEDSGGLLSFLSCQFMEDGELDLTSYFNPQAFHSGRLTHRRATRRRGDDRW
What is the function of this protein?
Dehydrogenase involved in the conversion of monodictyphenone to the prenyl xanthones such as emericellin, shamixanthone and epishamixanthone (PubMed:21351751, PubMed:22730213).  Monodictyphenone is first converted to variecoxanthone A via a paeciloxanthone intermediate by the consecutive actions of the FAD-dependent monooxygenase mdpD and the xanthone prenyltransferase xptB (PubMed:21351751).  XptB catalyzes regular O-prenylation at the hydroxy group of C-7 of the xanthone ring (PubMed:23150454).  Variecoxanthone A is further prenylated to emericellin by xptA before being reduced to shamixanthone and epishamixanthone by the dehydrogenase xptC (PubMed:21351751).
What are the official names of this protein?
Xanthone prenyltransferase B.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: TSAD_KLEP3
Sequence: MRVLGIETSCDETGIAIYDDQQGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPAFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKMAAQGTEGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRNNGDDEQTRADIARAFEDAVVDTLMIKCRRALEQTGFKRLVMAGGVSANRTLRAKLAEMMQKRGGEVFYARPEFCTDNGAMIAYAGMVRLQTGAKAELGVTVRPRWPLAELPAA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DVL11_ARATH
Sequence: MASSSSLTRSGSVHLDEKWKLSKKDGGASRITRSSSTSSSSFNGKKQGRCAFTRKCARLVKEQRARFYIMRRCVIMLICWRDNYSDS
What is the function of this protein?
Small polypeptide acting as a regulatory molecule which coordinates cellular responses required for differentiation, growth and development, probably by restricting polar cell proliferation in lateral organs and coordinating socket cell recruitment and differentiation at trichome sites.
What are the official names of this protein?
Small polypeptide DEVIL 11, Small polypeptide ROTUNDIFOLIA LIKE 8, Small polypeptide ROT-FOUR-LIKE 8.
What is the protein family that this protein belongs to?
Belongs to the DVL/RTFL small polypeptides family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.