PharMolix/UniProtQA huggingface dataset:
Protein: DAPE_SHEB8
Sequence: MIPADDYPVTELTKALIARPSVTPLDEGCQTLMAERLSAIGFNIEPMVFEDTTNMWARRGNEGPVFCFAGHTDVVPTGDVSRWHTPPFVPTIIDGYLYGRGAADMKGSLAAMVIATERFVAKHPDHNGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWALVGEPSSTLKLGDVVKNGRRGSLTGNLIVKGIQGHVAYPHLADNPIHKAAPFLAELSQMHWDNGNEFFPPTSFQIANINGGTGASNVIPGALDVMFNFRYSTEVTAEILIERVEALLKAHELGYDISWIFNGLPFLTGDGPLLDATRIAIRQVTGYETDPQTTGGTSDGRFIAPTGAKVLELGPVNATIHKVNECVKVDDLEQLALCYEVILEQLLC
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: PURA2_BOVIN
Sequence: MAFAETNPATSSLPNGDCGRPRTRPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSDFGGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMERIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGEIIPHFPANQEVLNKVEVQYKTLPGWNTDISNARTFKELPINAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase isozyme 2, AMPSase 2, AdSS 2, Adenylosuccinate synthetase, acidic isozyme, Adenylosuccinate synthetase, liver isozyme, L-type adenylosuccinate synthetase, IMP--aspartate ligase 2.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: SDHE_VIBVU
Sequence: MYTTEEKARIRWACRRGMLELDVVVMPFFEECFEKLSEQEQRDFVSLLECDDPDLFTWVMGHGRSENLGHASMVDKIVAHNLSKVR
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_PHYS2
Sequence: MGQKTNPNGLRLGIIRTWESQWYVNDKEIPNLIKEDFLIRKLINNFAKKSAISQIDIERLKEKNKNRITIFVHTAKPGVIIGKDGDTRNKLVVKLKELTQKEVNLNVLEVKNSDKIALLIAQNMAEQLENRMFFRRVQKMAIQKALKAGAKGVKTLISGRLGGAEIARSEGHAEGRVPLHTLRADIDYAAVEAHTTYGVLGIKVWIFHGEVLPGQTILDTRKPFASQSSNTPNRRPRNFKGGNNNHVNAKKN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL20_FERNB
Sequence: MRVKNAVNSKKKKKKILKFVKGFRGALRRRYSLAKQSYYRALKFAFDGRRNKKGNFRKIWITRINIAARNAGLKYNELIHGLKLANVAINRKMLAELAVNDPESFKEYVNIAKAALGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: IOLA1_OCEIH
Sequence: MISSETKHMQNYINGKWVDAKSGKQEVIPNPATGETIATVTISDVEDVDMAVAAAKEVFPEWSDIPVPNRTRYLLDYWKLLQDNKEELAKIITLENGKSLRDAQGEVQRGIEVVELATSTPSMMMGDALPSIAKGIDGSIWRYPLGVVAGITPFNFPMMVPLWMFPLAIACGNTFVLKTSERTPILAERLVELFYEAGFPKGVLNLVHGGKEVVNRFLTHPDIEAVSFVGSEPVAKHVYQTGTAHGKRVQALAGAKNHAVVMPDCDVEKTIQGVLGAAFGSSGERCMACSVVAVVDDIADEFLEKLVKETKKLRVGDGMDDSNFIGPVIRESHKERVLSYIDSGVDEGAHLLVDGRKIKEETPDGYYVGATIFDHVTQDMKIWQDEIFAPVLSVVRVSDLEEGIRVTNQSKFANGAVIYTNSGKSAQQFRNRIDAGMIGVNVNVPAPMAFFSFAGNKASFYGDLGTNGKDGVQFYTRKKVVTERWF
What is the function of this protein?
Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively.
What are the official names of this protein?
Malonate-semialdehyde dehydrogenase 1, MSA dehydrogenase 1, Methylmalonate-semialdehyde dehydrogenase 1, MMSA dehydrogenase 1, MSDH 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. IolA subfamily.
Protein: P49_STRLI
Sequence: MLDAVVVGAGPNGLTAAVELARRGFPVAVFEAQGTVGGGARTEELTLPGFRHDPCSAAHPLGINSPAFRGLPLERYGLEWLHPGLPMAHPFPDGSAAVLSRSVGETAASFGARDAGPYRRLIERFLPRWDTLARDFMSLPLTALPRDPVTLARFGLVGLPPSTWLMRRFRDEKAKTLFAGLVAHVMAPLGGFATGAIGLVFALAAHARGWPVARGGSQSISDALTAYLKDLGGAVHTDYEVKRLDDLPPARAYVLDTSPTALARIAGLGSHYANYRYGPSVFKIDYALDGPVPWTAEEPRSAGTVQIGADSTEIGAALHAPSGTDRAPERPFLITVQPSVADPTRAPAGKHVFWAYGHVPNGWNGDLTDAMERQLERFAPGFRDRVLARATAGPAELAARNANYVGGDISSGAVSGLQLLLRPKISLFPYSTPHPAVFICSSATPPGPGVHGMSGHNAAKAVWRRLRQT
What are the official names of this protein?
Protein p49.
Protein: G6PI_STRPG
Sequence: MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKEEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_ACOAM
Sequence: MPKKKGFTPLPYLASIVFLPWWVSLSFNKSLEPWVTNWWNTRQSETFLNDIQERNVLERFIELEELFLLDEMLKENPETRMKNLRIGIHNETIQLVKTDNEYHLHTILHFSTNIICFAILSVYSILGNEELVILNSWVQEFLYNLSDTIKAFSILLVTDLWIGFHSPHGWELMIGSVYNDFGLAHNEQIISGLVSTFPVILDTIVKYWIFHYLNRVSPSLVVIYHSMND
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: Z385A_HUMAN
Sequence: MILGSLSRAGPLPLLRQPPIMQPPLDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNICQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPGVREPGDPAPPGSTPTNGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSIPETGQGVTKGEGGTPAPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKSRGAGELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY
What is the function of this protein?
RNA-binding protein that affects the localization and the translation of a subset of mRNA.  May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation.  Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation.  With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A.  Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity.  May also bind CCNB1 mRNA.  Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction.  Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes.  May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest.  Also plays a role in megakaryocytes differentiation.
What are the official names of this protein?
Zinc finger protein 385A, Hematopoietic zinc finger protein, Retinal zinc finger protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Cell projection, dendrite. Note=Detected in dendrites of Purkinje cells and hippocampal neurons.
Protein: ILVC_ENT38
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELVPQADLVVNLTPDKQHSDVVRSVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMSDWANDDKNLLTWREETGKTAFETASQFDGKISEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKEFMTTLQTGDLGKAVAEGAVDNAQLRDVNEAIRSHAIESVGHTLRGYMKDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MVP_TMVOM
Sequence: MALVVKGKVNINEFIDLTKMEKILPSMFTPVKSVMCSKVDKIMVHENESLSEVNLLKGVKLIDSGYVCLAGLVVTGEWNLPDNCRGGVSVCLVDKRMERADEATLGSYYTAAAKKRFQFKVVPNYAITTQDAMKNVWQVLVNIRNVKMSAGFCPLSLEFVSVCIVYRNNIKLGLREKITSVRDGGPMELTEEVVDEFMEDVPMSIRLAKFRSRTGKKSDVRKGKISSSDRSAPNKNYRNVKDFGGMSFKKNNLIDDDSETTVAESDSF
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.  Triggers host hypersensitive defense reaction in incompatible plants harboring resistance (R) proteins.
What are the official names of this protein?
Movement protein, 30 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma. Note=Binds to the host cytoskeleton before being transported to the host plasmodesmata. Observed in virus replication complexes (VRCs) of tobamovirus infected host cells (By similarity). In resistant plants, targeted to the host plasma membrane via the interaction with host resistance (R) protein TM-2 (e.g. tomato ToMV resistance protein TM-2(2), AC Q71BG9) (By similarity).
Protein: EPCR_BOVIN
Sequence: MLTTLLPLLPLLLPGWALCSQEASDGPWDLHMTQVSYFRNPSQVWHRGNATLGGVLTHVLEGPGRNVSIQQLQPLQEPDSWALTKIYLNRYLEEFVGLVQVVHQERGVTFPLIIRCFLGCELPPEGSEARVFFEVAVNGSSFVNFQPKTASWVAEPHAPSRVVTYTVDQLNKYNRTRYELREFLQDTCVQYIQKHITTNNLKGSQTGRSYTSLVLGVLVGCFIVTGVAVGIFLCTGGRRRC
What is the function of this protein?
Binds activated protein C.  Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation.
What are the official names of this protein?
Endothelial protein C receptor, Activated protein C receptor, APC receptor, Endothelial cell protein C receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: KCY_LACLA
Sequence: MKKIQIAIDGPASSGKSTVAKIIARNLDLIYLDTGAMYRVATFVALQKETDDAKEIIEFIEKNPISFMNGQKGQEVLMGSENVTEVIRTNEVTNTVSKISAMTEIREFMVAEQQRIAKNGGIIMDGRDIGTVVLPKADLKIFLVASVDERAERRYKENLSKGIPTDLERLKIEISERDRKDSTRAISPLKQAEDAILLDSTGKTINEIVQFIEDKAKELM
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNGF_LISIN
Sequence: MSKETKPKVVVIGGGTGLPVVLKGLKKKEIHLTAIVTVADDGGSSGKIREQMDVLPPGDIRNVMLALSNVDPRVVDLFQYRFAVDGDLSGHVIGNLILTALSQLNDSYVDAINVLATVLKIRGKVIPATDQPLILNAEMEDGSIVHGESLIPLQGKHINRVFIEPENVKPYPTAVEAVKEADLIVIGPGSLYTSILPNLLLEELAEEITASKAQKVYITNILTQIGETDFFSDADHIKVIHEHVGKSFIDKTLINTTTVPKELLFPEDVAQVEHNAEEMEKLGVEAIYQDFLSTEDGLVRHAADKVADALLAMLPNKNNEKE
What is the function of this protein?
Required for morphogenesis under gluconeogenic growth conditions.
What are the official names of this protein?
Gluconeogenesis factor.
What is the protein family that this protein belongs to?
Belongs to the gluconeogenesis factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SHEB9
Sequence: MSITKDQILEAFAAMSVMEVVELIEAMEEKFGVSAAAAVVSGGAEAAVVEEQTEFNVVLTAHGDNKVAVIKAIRGATGLGLKEAKAMSEAAPVAVKEGVSKEEAEALKKELTEAGASVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: IHFB_BRUA1
Sequence: MIKSELVQIIASRNPHLFQRDVENIVGAVFDEITNALAEGNRVELRGFGAFSVKNRPARSGRNPRTGETVDVEEKWVPFFKTGKKLRDRLNGAV
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: HSP9_SCHPO
Sequence: MSDPARKSFTEQGKEKMTPDSSKSTLDKAKESITGAYDKVASAFTSDEDKSTSQEAHDKAQRFVDDKL
What are the official names of this protein?
Heat shock protein hsp9.
What is the protein family that this protein belongs to?
To yeast HSP12/GLP1 and C.albicans WH11.
Protein: AROA_CROS8
Sequence: MQESLTLQPIARVDGTINLPGSKSVSNRALLLAALAKGTTTLTNLLDSDDVRHMLNALNALGVHYSLSDDRTRCEIQGQGGPFNTLVELELFLGNAGTAMRPLAAALCLGTNNVVLTGEPRMKERPIGHLVDALRQGGADVTYLEQENYPPLHLKGGFTGGNVTVDGSVSSQFLTALLMAAPLAPGNTAIDIKGELVSKPYIDITLHLMKTFGVEVENQNYQRFVIQGGQQYQSPGHYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSVQGDIRFADVLEKMGAHITWGDDFISCTRGELNAIDMDMNHIPDAAMTIATTALFAKGTTTLRNIYNWRVKETDRLAAMATELRKVGATVEEGHDFITVTPPAQLQFADIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPNYFAQLARISHSA
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1082_PASMU
Sequence: MTLIEKLRKIEDYVLQHCQYRFYFAKSPFGMALRAQYYYYPEDIPEATKNLANHFLTQAGYEDFYTPLEALMSKANITPPSPAEMIEGGNWRFFAIKFNFFSPLNPALKKYYNTEYVTFICIPCQDHEGQDSMELLYTSPTTGNLFKEMGNSQLLDPNCEADQAYLQLLEEAVDFMCEKLDIDAPEPIDITEALHDFTTLLNIHDKEEFIKRYQQIQETPEKCLLDLVEQGYADAEEGDKPELAFLRYRFLLQPMLDSFDTDWCIDNEELSEYLSNVIGKKFKLPQKALEPYEIVERLEKKSDYTLLNIETEQDSYSLFVCKQKDKKRILQLARMLDFAIVPF
What are the official names of this protein?
Uncharacterized protein PM1082.
What is the protein family that this protein belongs to?
To P.multocida PM0657.
Protein: COXX_PAEAT
Sequence: MTAAVSTTDTPLNASPARGSIGISRKFKAYLALTKPRVIELLLVSTLPTMIFAQRGFPSIGLILATLVGGAFAAGSAGVFNCYIDRDIDKLMHRTEKRPLVTGEVTPREALVFAWILGAASIAILWFGANPLSAWLGLGAIVFYVVIYTMILKRRTAQNIVWGGAAGCFPVLIAWAAVTNTVEWPAIVLFMVIFLWTPPHYWPLSMRYGEDYRNAKVPMLGAIAGAKVVSVQVVLYAWAMVACSLLMVPVGGAGWVYTIAAVAAGAWFLYESHALYKRAQGGDVSNKGAMKVFHGSISYLTLLFIALAVDPFVGSAIVGS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: G6PI_ACAM1
Sequence: MDAAALWQRYQDWLYYHEQLGIYVDISRMSFDDAFVERLEPKFVKAFKEMDALEAGAIANPDENRMVGHYWLRDSNLAPTPELKKEIITTLEKIEAFAADVHAGRIKPATAPRFTDVISIGIGGSSLGPQFVSQALAVLHPALELHFIDNTDPAGIDYILDRVQDRLDTTLVVTISKSGGTPETRNGMLEAKNRFKNLGLDFPKHAVAVTGYGSKLAQIAEEEGWLAMLPMHDWVGGRTSELSAVGLVPASLQGIAIREMLAGAKAMDEATRVHDLKTNPAALLALSWYFAGEGAGKKDMVILPYKDSLMLFSRYLQQLVMESLGKEKDLDDKIVHQGIAVYGNKGSTDQHAYVQELREGIPNFFLTFIEVLKDRDGTRFEVEPGVTSGDYLSGFLLGTREALYEKRRDSITVTLPEVTSKQVGALIALYERAVGLYASLINVNAYHQPGVEAGKKAATDTIALQNKIVQILRNTLTPLPITSLADKAEAPDKIETVYKIVRHLAANKRGVELYGNPAEPGSLQVTLKG
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CASP5_ORYSI
Sequence: MEAGEEIEDGEPSTPTYKAHHPPPHLPPPMRSSGVSLVLSVADLVLRFVAIGGTAGSAIAMATTSETLPFAAPFVRFRAEYSDLPTLMFFVVASSVVCAYLVLSLPASVVHVVRPGARSSRAILAFLDTVMLALLTASASAAAAIVYLAHRGSARANWLGICQQFTSFCQRITASLVGSFAAAVVLVALVFLSALSLARRA
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 5, OsCASP5.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: IBP1_RAT
Sequence: MPEFLTVVSWPFLILLSFQVRVVAGAPQPWHCAPCTAERLELCPPVPASCPEISRPAGCGCCPTCALPLGAACGVATARCAQGLSCRALPGEPRPLHALTRGQGACVLEPAAPATSSLSGSQHEEAKAAVASEDELAESPEMTEEQLLDSFHLMAPSREDQPILWNAISTYSSMRAREITDLKKWKEPCQRELYKVLERLAAAQQKAGDEIYKFYLPNCNKNGFYHSKQCETSLDGEAGLCWCVYPWSGKKIPGSLETRGDPNCHQYFNVQN
What is the function of this protein?
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture.  They alter the interaction of IGFs with their cell surface receptors.  Promotes cell migration (By similarity).
What are the official names of this protein?
Insulin-like growth factor-binding protein 1, IBP-1, IGF-binding protein 1, IGFBP-1.
What are the subcellular locations of this protein?
Secreted.
Protein: GLGA_SYNPW
Sequence: MRVLFAAAECAPMVKVGGMGDVVGSLPPALAQLGHDVRLIMPGYGKLWSSLDIPAEPIWRAQTMGTEFAVFETRHPTNGLPLYLVGHPVFDPERIYGGEDEDWRFTFFASAAAEFSWNVWKPQVLHCHDWHTGMIPVWMHQDPEISTVFTIHNLKYQGPWRWKLDRITWCPWYMQGDHTMAAALLYADRVNAVSPTYAQEIRTSEYGEKLEGLLNYISGKLRGILNGIDLEAWNPATDKALPATFSSANLAGKATCKQVLQERMGLTLNPDTFLLGMVSRLVDQKGVDLLLQVADRLLAYTDTQIVVLGTGDRGLESGLWQLASRHPGRVAVFLTYDDALSRLIYAGSDAFLMPSRFEPCGISQLYAMRYGCVPVVRKVGGLVDTVPPHDPRQKSGTGFCFDRFEPVDFYTALVRAWEAFRHPESWKELQRRGMEQDYSWARSALEYDRMYRDVCGLKEPSPDAAAVEQFSQGQEADPSRHGGASQTLSPSEEAPIESSEASSGSTPVRTSRNPLARLLGKQRR
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: TX35E_CTEON
Sequence: GCGDINAACKSDCDCCGNSVTCDCYFTDCKCRESAIRKQF
What is the function of this protein?
Insecticidal neurotoxin that reversibly inhibits the N-methyl-D-aspartate (NMDA)-subtype of ionotropic glutamate receptor (GRIN) and inhibits inactivation of insect sodium channels (Nav).  In vivo, is highly toxic to insects.
What are the official names of this protein?
U12-ctenitoxin-Co1a, U12-CNTX-Co1a, Neurotoxin Oc M14-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 03 (Tx2) family. 05 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IPT5_ARATH
Sequence: MKPCMTALRQVIQPLSLNFQGNMVDVPFFRRKDKVVFVMGATGTGKSRLAIDLATRFPAEIVNSDKIQVYKGLDIVTNKVTPEESLGVPHHLLGTVHDTYEDFTAEDFQREAIRAVESIVQRDRVPIIAGGSNSYIEALVNDCVDFRLRYNCCFLWVDVSRPVLHSFVSERVDKMVDMGLVDEVRRIFDPSSSDYSAGIRRAIGVPELDEFLRSEMRNYPAETTERLLETAIEKIKENTCLLACRQLQKIQRLYKQWKWNMHRVDATEVFLRRGEEADEAWDNSVAHPSALAVEKFLSYSDDHHLEGANILLPEISAVPPLPAAVAAISR
What is the function of this protein?
Involved in cytokinin biosynthesis.  Catalyzes the transfer of an isopentenyl group from dimethylallyl diphosphate (DMAPP) to ATP and ADP.
What are the official names of this protein?
Adenylate isopentenyltransferase 5, chloroplastic, AtIPT5, Adenylate dimethylallyltransferase 5, Cytokinin synthase 5.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: PETN_STAPU
Sequence: MDIISIGWVSLMVVFTFSISLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: RS4_COXBU
Sequence: MARYLGPKCRLSRREKTDLQLKSGIRAIDSKCNIERIPGMHWQRRGRTTDYGVQLRMKQMIKRYYDVLEKQFANYYKQADRLKGSTGDNLLKLLESRLDNVVYRMGFAATRAEARQLISHKAILVNGEVVNIPSYQVKPGDIIEVRSRAKGQLRIKGALELAQQRAPISWIEVDTKKMTGTFKEQPDVAELPAEFKVNLVVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.