PharMolix/UniProtQA huggingface dataset:
Protein: MCRC_METVA
Sequence: MPVGRKEQIVDCRAVMGLGEGGGLAQRGTFAEGLRNDVVVVAMSPGRRHITKPVCEITYGIREAGIQTSVLVLDAGGGIPSDAPQGSLGSTFGLKPDEARQVNRHKLCVIHFGNVKSHIIYKARLFLKYVTIPTIIVCQSPVDMEDFAKIGIKTLDVMPLEPKTEGTIVEIITGVVRGESSPQKKIDEIIESIKKHLG
What are the official names of this protein?
Methyl-coenzyme M reductase operon protein C.
Protein: RNPH_CAUVC
Sequence: MRPSERAPDQLRAVTLETGVNRYAEGSCLIGFGHTKVLVTATVEENVPGWMRNKGAGWVTAEYGMLPRATHTRGRREAAAGKQTGRTQEIQRLIGRSLRAVVDLKALGERQITLDCDVVQADGGTRTAAITGAWVALRLATKYLLDEGVLKTDPILGQVAAVSCGVFNGVPVLDLDYEEDSNAEADSNFVLTGVGDIVEIQATGEKRGFTRAEFESLYGLAEKGINELFALQRAAIGG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: MIAB_RUEST
Sequence: MSAPKKLYIKTYGCQMNVYDSERMAETLGGQGYVETQTPDDADMILLNTCHIREKAAEKVYSELGRFKGLKAEKPDLKIGVAGCVAQAEGEEIMRRQPLVDLVVGPQSYHRLPEMEAKAGTGEKVLDTDFPEEDKFEKLKRRPKAKRGPTAFLTVQEGCDKFCAFCVVPYTRGAEVSRPVDRVLREAEDLVERGVREITLLGQNVNAYHGAGPNGDMTLAQLIWELDKIDGLERIRFTTSHPNDMMDDLIEAHGTCKKLMPYLHLPVQAGSDKILKRMNRSHTAESYIRLIERIRAARPDILISGDFIVGFPEETEEDFQATLDLVEEVKYGTAYSFKYSTRPGTPAAERAQVDPKEADDRLQRLQAVLTRQQREVQDSMVGRELGVLFEKAGRFAGQMVGKSDYLHAVHVADCDAKIGDLRRVRIVSSGANSLAGELID
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B7_USTMD
Sequence: MSSDPNFSLTSFLECLSQIEHEFLRDKVENPPVLVRKLQELQQKTPGHVASLLHDPETIQQIHQTAHRIEVAVKVFIHIDQKFTSGCSEVVHGTSKVMQEVNVGSPAVGCRNLSEDLPAYHMRKHFLLTLDSPYPTQEEKEGLVRLTNESTARVGLSNATRPPLEVHQLTLWFINARRRSGWSHILKKFAREDRSRMKRLVRAKLSSSTQSSPPSPMPEYPSNNLDNILSDNLGRPLTPADKQQFEDDWASMISWIKYGVKEKVGDWVYDLCAASKKTPKPGMPRPVTTVAKRQPARKTKPAAKPNSRTANPRASTTPSIDSTLDSSKLESTPELSMCSTADTSFSTFGSSLSMSHYNPFQDGNDILQSPTVKARGNRKVKALPKRAGKQQPDEVENGKIPFLCLSVAFV
What is the function of this protein?
The B locus has at least 25 alleles, and any combination of two different B alleles yields a multimeric regulatory protein, that activates genes responsible for the pathogenicity and for the sexual development of the fungus within the corn plant.
What are the official names of this protein?
Mating-type locus allele B7 protein.
What is the protein family that this protein belongs to?
Belongs to the TALE/M-ATYP homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: VTM2A_HUMAN
Sequence: MMGIFLVYVGFVFFSVLYVQQGLSSQAKFTEFPRNVTATEGQNVEMSCAFQSGSASVYLEIQWWFLRGPEDLDPGAEGAGAQVELLPDRDPDSDGTKISTVKVQGNDISHKLQISKVRKKDEGLYECRVTDANYGELQEHKAQAYLKVNANSHARRMQAFEASPMWLQDMKPRKNVSAAIPSSIHGSANQRTHSTSSPQVVAKIPKQSPQSGARIATSHGLSVLLLVCGFVKGALL
What is the function of this protein?
Plays a role in the regulation of the early stage of white and brown preadipocyte cell differentiation.  Promotes adipogenic commitment of preadipocytes by increasing gene expression of the transcription factor PPARG in a BMP4-dependent signaling pathway.
What are the official names of this protein?
V-set and transmembrane domain-containing protein 2A.
What are the subcellular locations of this protein?
Secreted. Note=Secreted by adipose precursor cells (By similarity). Not detected in the nucleus (PubMed:28052263).
Protein: CAP8_ADEB3
Sequence: LIKQPVVGTTHVEMPRNEVLEQHLTSHGAQIAGGGAAGDYFKSPTSARTLIPLTASCLRPDGVFQLGGGSRSSFNPLQTDFAFHALPSRPRHGGIGSRQFVEEFVPAVYLNPYSGPPDSYPDQFIRHYNVYSNSVSGYS
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.
What are the official names of this protein?
Pre-hexon-linking protein VIII, Pre-protein VIII, pVIII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein family.
What are the subcellular locations of this protein?
[Pre-hexon-linking protein VIII]: Host nucleus. SUBCELLULAR LOCATION: [Hexon-linking protein-N]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion. SUBCELLULAR LOCATION: [Hexon-linking protein-C]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion.
Protein: TBB6_HUMAN
Sequence: MREIVHIQAGQCGNQIGTKFWEVISDEHGIDPAGGYVGDSALQLERINVYYNESSSQKYVPRAALVDLEPGTMDSVRSGPFGQLFRPDNFIFGQTGAGNNWAKGHYTEGAELVDAVLDVVRKECEHCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDARNMMAACDPRHGRYLTVATVFRGPMSMKEVDEQMLAIQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMASTFIGNSTAIQELFKRISEQFSAMFRRKAFLHWFTGEGMDEMEFTEAESNMNDLVSEYQQYQDATANDGEEAFEDEEEEIDG
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-6 chain, Tubulin beta class V.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FABH_HELPG
Sequence: MEFYASLKSIAMHVPSERVKNAEFQQFLDTSDEWIEKRTGIKERRFASNEEKSSDLGVIAAKQAIERAHLTPKDIDLVVVATLSPDFLAMPSTACVLSAKLGIENKPAFDISAACTGFIYLLSVAKAYVESGMCENVLIVGAEKTSSVLDFKDRGTCILFGDGAGACVIGRTKRLKESILDVQISANGNFSNYLYTPRTLKPTPFNAKEEALEPFLCMKGNEVFKLAVKTLLKDVEMILEKNALKPEDVRLFIPHQANFRIIQAVREHLDFKDEQVVLTVHKYGNTSAASIPMAMGEAYEEGRLKKGDLMLLDAFGGGLTWGSALVYFGG
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCPG_DROME
Sequence: MFGGQQPILVLSQNTKRESGRKVQLENIQAGKAIADVIRTCLGPQAMLKMLMDPMGGIVMTNDGNAILREITVQHPAAKSMIEIARTQDEEVGDGTTSVIVLAGEMLAAAEPFLQQQIHPTVIIRAYREALEDIVGHLQSQLSIQLDVKDKAKMADVVKACVGTKFIGKWSDLAVKIALDAVETVTLSENGRLEVDIKRYAKVEKIPGGAIEESCVLKGVMINKDVTHPKMRRLIENPRIVLLDCSLEYKKGESQTNVEIIGEQDFTRMLQIEEEFVQRICADIIAVKPDLVFTEKGVSDLAQHYLLKAGITAIRRLRKTDNLRIARACGATIVNRTEELTEKDVGTGAGLFEVKKIGDEYFTFVTECKEPKACTILLRGASKDILNETERNLQDALHVARNLVLEPRLVAGGGAVEMAASQLLTRKQVKGPYTAVAHALEIIPRTLAQNCGANTIRALTALRAKHASHTGDGVCAWGIDGESGEIVDMNVKNIWEPLAVKLQTYKTAVETAILLLRIDDIVSGSKKRGGNEPTNPAAMAQGQE
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma, Chaperonin containing TCP1 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN1_CLAL4
Sequence: MGVKGLNQLIKEHAPDAFKEYQLKNLFGRKVAIDASMCLYQYLIAVRQQDGQQLTSEDGETTSHLSGMFYRTIRLVESGLKPMYVFDGKPPVLKGGELEKRLLKRQDALKQIEDLKETGTVEELMKYEKRTVRASREQNDEAKKLLELMGIPYIVAPSEAEAQCAELARAGKVFAAASEDMDTLCYEPKYLLRHLTVAEARKMPIDQIDYEAMLKGLDMDRSTFVDLCILLGCDYCETIKGVGPVTAFKLIKEHGSLDNIVKWIQENPEKTKYKVPENWPYDEAKQLFMNPEITKGDEVDVKWNEPNVDGLVEFMVKQKGFSEERIRSGAEKLKKALKGGVQGRLDGFFTVVKSSPAKRKPDAKDAKGKGKKKAKR
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: RS21_XANOR
Sequence: MPSVKVRENEPFEFALRRFKRTCEKAGVLAETRKREFYEKPTQERKRKAAAAVKRQLRRSSRDVTKRQRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: CODY_CLOPS
Sequence: MSTLLSKTRRLNKILQKSGTEAIAFGDICQLLSDVMSCNVYLVGRKGRILGYSFSEKFECDIMKEKVVVDRKFPEDYNNKLINIQDTIANIPNKGICVFEGVGECLISKKISTIVPIVGNGDRLGTLLLARFGEEFNDDDLVLAEYSATIVGMELLRARQGEIEEEARKKAVVQLAIGTLSYSELEAVEHIFSELNGDEGLLVASKIADKVGITRSVIVNALRKFESAGVIESRSLGMKGTHIKILNEKLMDELKKIK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADL_SALTY
Sequence: MSQKTLFTKSALAVAVAIISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSRRTLDADNIAPTAWVPNVHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYRLNEAWSFGLGFDAVYARAKIERFAGDLGQLVAAQNPALAPVAGQIPSDTKIAHLNGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLPIAINRFNLPIPTATGGATQSGYLTLNLPEMWEVSGYNRVAPQWAIHYSLAYTSWSQFQELKAKSTAGDTLFEKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTTYAFNKDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF
What is the function of this protein?
Involved in translocation of long-chain fatty acids across the outer membrane.  FadL may form a specific channel (By similarity).
What are the official names of this protein?
Long-chain fatty acid transport protein, Outer membrane FadL protein, Outer membrane flp protein.
What is the protein family that this protein belongs to?
Belongs to the OmpP1/FadL family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: YIDF_ECOLI
Sequence: MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLIPYLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDATLQKWCGSENPQPRCDCQACDWHRLCPHARQETPDSVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMELMTMLR
What are the official names of this protein?
Uncharacterized protein YidF.
Protein: DBP1_CANGA
Sequence: MSDGSGRYVPPHIRRGGGNSHESAAADGLSGSRYSGNGFFSSPNRGNHKSSGGFFGSRPFNDRRTGQGSRASGSGGFGGSGGRYGWVNGKHVPYPKNPRLEMELFGNATDHVTSGINFDNYDDIPVEASGDNVPEAITEFKSPPLDELLLENVELANFSKPTPVQKYSIPIVTKNRDLMACAQTGSGKTGGFLFPVLSELFLNGPAPLPEHTRHSYMRKCYPSALVLAPTRELAIQIFDEAKKYTYRSWVKPYVVYGGAPIGQQMRDMDRGCNLLVATPGRLNDLLERGKISLVNVKYLVLDEADRMLDMGFEPQIRHIVEDCDMPSVNDRQTLMFSATFPREIQHLARDFLKDYIFLSVGRVGSTSENIQQKVLFVEDYDKNSALLDILINEIDGLTLVFVETKRMADQLTDFLIVQNFKATAIHGDRTQAERERALHAFRNGIANILVATAVAARGLDIPNVTNVINYDLPTDIDDYVHRIGRTGRAGNVGVATSFFNSNSMNIAKELMDLLTEANQEVPQFLVNMVQDSMRFGRGGRNSRTGSNRGRGSNTRDYRHSNKDDWGSLGSSRRGFRSNDNRGFGNNWGSSSGDGFTNKAANSWW
What is the function of this protein?
ATP-binding RNA helicase involved in translation initiation.  Remodels RNA in response to ADP and ATP concentrations by facilitating disruption, but also formation of RNA duplexes.  Redundant to DED1, may be required in conditions in which DED1 expression is decreased (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX3/DED1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTGDS_SHEEP
Sequence: MATPNRPWMGLLLLGVLGVLQTPAPTEAALQPNFEEDKFLGRWFTSGLASNSSWFLEKRKVLSMCKSEVAPAADGGLNVTSTFLRKDQCETRTLLLRPAGPPGCYSYTSPHWSSTHEVSVAETDYETYALLYTESVRGPGPDSLMATLYSRTQTPRAEVKEKFTTFARSLGFTEEGIVFLPKTDKCMEVRT
What is the function of this protein?
Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation.  Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes.  Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophobic molecules and as a secretory retinoid and thyroid hormone transporter.  Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier.  It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system (By similarity).  Involved in PLA2G3-dependent maturation of mast cells.  PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR (By similarity).
What are the official names of this protein?
Prostaglandin-H2 D-isomerase, Glutathione-independent PGD synthase, Lipocalin-type prostaglandin-D synthase, Prostaglandin-D2 synthase, PGD2 synthase, PGDS, PGDS2.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Nucleus membrane. Golgi apparatus. Cytoplasm, perinuclear region. Secreted. Note=Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.
Protein: TR104_RAT
Sequence: MLSMLESILLSVATSEAMLGILGNIFIVLVNCTNWVRNKKLSKINFILTGLAISRVFTIWIITLDAYTKVFFLTTLMPSNLHECISYIWVIINHLSVWFATSLSIFYFLKIANFSHYIFLWLKRRADKVFVFLIGYLIITWLASFPLAVTVIKNIKVHHNNTSWLIQLEKRELLINYVFANMGPISLFMVAVFTCFLLTISLWRHRRRMQSTGSKFRDLNTEVHVKAMKVLISFIILFILYFMGVLIETLCLFLTENILLFIFGFTLSSTYPCCHSFILILTSRELKQASMRALQRLKCCET
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 104, T2R104, Taste receptor type 2 member 21, T2R21.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: P2C55_ORYSJ
Sequence: MRRHHLLGLLRRAAASSTSAASSRAGPHPSLHAPGPLRNGGSAPRFFSSRGGAGAASKGLGDDEVELYSLLLGVSIGDEGEASSRGPAASRGGRRGRNSKRQPPRSRFDGDGVGCSKDGKLSWGYSSFQGRRPSMEDRLSIKSTTVNGETVSLFGVFDGHGGPRAAEYLKKHLFKNLVKHPKFLKDTKLAINQTFLKTDADFLQSISSDRYRDDGSTAVAAILIGNRLYVANVGDSRAVALKAGKAVPLSEDHKPNKKDERKRIEDAGGIVVSDDIWRVDGILAVSRAFGNRLMKRYVKAEPNIQEKVVDEGLEYLVLATDGLWDVMRNEDAVSLLKAQDGPKAAAMKLTEVARSRLTLDNVTCIVLQFHHGKSTNSK
What are the official names of this protein?
Probable protein phosphatase 2C 55, OsPP2C55.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: VPR_SIVCZ
Sequence: MEQAPEDQGPPREPYQEWALETLEELKNEAVRHFPRPWLHQLGQFIYDTYGDTWVGVEAIIRILQHLLFIHFRLGCQHSRIGILPQRRRSNGSNRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: METJ_ECO57
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_DESVV
Sequence: MSEQKTLSVQKRDNLGKGANRRLRSEEVVPGVFYDTKGNNVAVQMPAKPLQKLFEEVGRTTVFQLEIEEEGKKSTHPVLIWDALFHPYKKKFTHIDFFGVDLDREIKIRVPLEFVGTSRGVKLGGKLEVYREFIDVMSKPLTLPKKITLDLTELDINSTIMLKDVAMPEGVRPATNENFAILSVLTPKSE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: GPPA_SALPC
Sequence: MNSTSLYAAIDLGSNSFHMLVVREAAESIQTLTRIKRKVRLAAGLNNDNHLSAEAMERGWQCLRLFAERLQDIPQPQIRVVATATLRLAVNAGEFIAKAQTILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFSDRNLAQENFDDAEKAARDVLRPVADELRFHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFTELNIQSMTLAGGALREGLVYGMLHLAVDQDIRSRTLRNIQRRFIVDTDQANRVAKLADNFLKQVENAWHIEPISRELLLSACQLHEIGLSVDFKQAPYHAAYLVRHLDLPGYTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAILFAGRRRDDLVPEITLRALNENLTLTLPGDWLAHHPLGKELIDQESQWQSYVHWPLDVR
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: OSTA_BOVIN
Sequence: MEPDRTQIRLDPRYTADLLEILKTNYSVPSACFSYPPTAAQLLRALGPVDISLMVIMTLFVLGSIAIFLEAAVYLHKNTRCPIKRKTLIWCSSSPTIVSAFSCFGLWIPRALTLVEMAITTFYSMCFYLLMQAMVEGFGGKEAVLRTLKDTPVMIHTGPCCCCCPCCPRIKITRKRLQLLLLGPIQYAFFKISLTLVGLFLIPDGIFDPSDISEGSTALWINTFLGVSTLSALWTIGIIFRQARLHLGEQNIGAKFVLFQALLILSALQPSIFSVLASGGQIACSPPFSSKIRSQVMNCHLLILESFLITVLTRIYYRRKDDKLGYEPFSSPDQDLNLKA
What is the function of this protein?
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood.  Efficiently transports the major species of bile acids (taurocholate) (By similarity).  Taurine conjugates are transported more efficiently across the basolateral membrane than glycine-conjugated bile acids (By similarity).  Can also transport steroids such as estrone 3-sulfate and dehydroepiandrosterone 3-sulfate, therefore playing a role in the enterohepatic circulation of sterols (By similarity).  Able to transport eicosanoids such as prostaglandin E2 (By similarity).
What are the official names of this protein?
Organic solute transporter subunit alpha, OST-alpha, Solute carrier family 51 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the OST-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Transported from the endoplasmic reticulum to the plasma membrane upon interacting with SLC51B. Mainly restricted to the lateral and basal membranes of ileal enterocytes (By similarity).
Protein: DAPAT_GEODF
Sequence: MAKINDNYLKLKAGYLFPEIGRRVRAFAEANPSAKVIRLGIGDVTRPLAPAVLKAFHDAVDDLATTDKFAGYGPEQGYDWLINAIIDKSYKPLGVSLKTEEIFISDGSKCDCANILDIFAMDNVVAIGDPVYPVYNDTNVMIGRTGEADEKGYYKGIVYMPCNEANGFIPELPKEKVDIIYLCFPNNPTGTVASKAELKKWVDYANANDAVIFFDAAYEAFITDPSIPHSIYEIEGAKKCAIEFRSFSKTAGFTGVRCGLVVVPEEVMGTTADGERYSFNRLWLRRTTTKFNGASYPVQRAAAAVYSDEGWKQTKEVIDYYMENARIIREGLKEVGVTVFGGVDAPYIWLKTPGGMTSWDFFDKLLTECNVVGTPGSGFGPSGEGYFRLSAFGHRENVIEAVERIKKNLK
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.