PharMolix/UniProtQA huggingface dataset:
Protein: OAT_BORPA
Sequence: MPAPAATRRDRIEDELGAHNYQPLDVVLARGSGVWLYDTAGRRYLDCLSAYSAVNQGHCHPRILAAMVEQAQRLTLTSRAFRHDQLAPLYEDLARLTGAHKVLPMNSGAEAVETALKAVRKWGYEARGVPAGQAEIIVCANNFHGRTLGIVGFSTDPDARGGYGPFAPGFTVVPFGDFAALQAAVTPRTVAFLVEPIQGEAGVILPPPGYFRQVRKLCSERDIVLILDEIQTGLGRTGAFLAEAHEGIEADVTLIGKALSGGFYPVSAVLSNQAVLGIFQPGQHGSTFGGNPLACAVARAALRVLHDEGMIDNAREQGAYFMQRLRALPGPVREVRGRGLMLALELEPDAGPARAYCERLMARGMLVKDTHGQTLRLSPPLIVTREQIDWACAQLAHVLAHSAPGSSGGPS
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG1_SHESR
Sequence: MDKTQSSQGKCPVMHGANSAVASNNMDWWPKALNLDILHQHDKKTDPMDPKFNYREAFNSLDLAAVKRDLNALMTDSQDWWPADWGHYGGLMIRMAWHSAGTYRVADGRGGAGTGNQRFAPLNSWPDNANLDKARRLLWPIKKKYGNKLSWADLMILAGNVAYESMGLKTYGFAGGREDIWHPEKDIYWGSEKQWLAPTENPNSRYSGERDLENPLAAVMMGLIYVNPEGVDGKPDPLRTAQDVRVTFARMAMNDEETVALTAGGHTVGKCHGNGKAQDLGPEPEGEELEAQGLGWLNKKGPGTGANAVTSGLEGAWTTHPTQWDNGYFHLLLNYDWELKKSPAGASQWEPINIKEEDKVVSVGDPNRKFNPIMTDADMAMKMDPEYRKISEKFYQDPAYFSEVFARAWFKLTHRDLGPKSRYLGPEVPNEDLLWQDPIPSVDYRLDASEIVDLKAKLLASGLSVSELVATAWDSARTFRGSDFRGGANGARIRLAPQKDWQANEPERLQKVLKVLTELQASLSKKVSIADLIVLGGAAAIEKAAHEAGVKVTVPFIPGRGDATQEMTDVESFAVLEPLHDAYRNWQKKDYVVQPEEMMLDRTQLMGLTAHEMTVLVGGMRVLGTNYGGTRHGVFTDKVGVLTNDFFVNLTDMAYNWKPAGSNLYQIVERKTGAVKWTASRVDLVFGSNSILRAYAEMYAQDDAKEKFVHDFVAAWTKVMNADRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: MUTS2_HELPJ
Sequence: MSDASKRSLNPTLMMNNNNTLPKPLEESLDLKEFIALFKTFFAKERGSIALENDLKQAFTYLNEVDAIGLPAPKSVKESDLIVVKLTKLGTLHLDEIYEIVKRLRYIVVLQNAFKPFTHLKFHERLNAIILPPFFNDLILLLDDEGQIKQGANATLDALNESLNRLKKESTKIIHHYAHSKELAPYLVDTQSHLKHGYECLLLKSGFSSAIKGVVLERSANGYFYLLPESAQKIAQKIAQIGNEIDCCIVEMCQTLSRSLQKHLLFLKFLFKEFDFLDSLQARLNFAKAYNLEFVMPSFTQKKMILENFSHPILKEPKPLNLKFEKSMLAVTGVNAGGKTMLLKSLLSAAFLSKHLIPMKINAHHSTIPYFREIHAIINDPQNSANNISTFAGRMKQFSALLSKENMLLGVDEIELGTDADEASSLYKTLLEKLLKQNNQIVITTHHKRLSVLMAENKEVELLAALYDEEKERPTYTFLKGVIGKSYAFETALRYGVPPFLIEKAKAFYGEDKEKLNVLIENSSTLERELKQKNEHLENALKEQEDLKNAWLLEMEKQKEIFHHKKLELEKSYQQALNILKSEVASKDTSSMHKEIHKASEILNKHKTDQEIPQIITSFQINEKARYKNESVLVIQILDKGYYLVETELGMRLKAHGSWLKQIQKPPKNKFKPPKTIVPKPKEASLRLDLRGQRSEEALDLLDAFLNDALLGGFEEVLICHGKGSGILEKFVKEFLKNHPKVVSFSDAPINLGGSGVKIVKL
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: YP276_YEAST
Sequence: MSKGKVLLVLYEGGKHAEEQEKLLGCIENELGIRNFIEEQGYELVTTIDKDPEPTSTVDRELKDAEIVITTPFFPAYISRNRIAEAPNLKLCVTAGVGSDHVDLEAANERKITVTEVTGSNVVSVAEHVMATILVLIRNYNGGHQ
What are the official names of this protein?
Putative uncharacterized protein YPL276W.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
Protein: APAG_SHESM
Sequence: MSALDDSIRVEVKTEYIEQQSSPEDQKYLFSYTITIVNLGEQAAKLETRHWIITDANGKISEVQGAGVVGETPTIPPNTAYQYTSGTVLDTPLGIMYGTYGMVSESGERFKATIKPFRLALPGLLH
What are the official names of this protein?
Protein ApaG.
Protein: MOAC_BORPE
Sequence: MSTTPTLSHLDESGQIRMVDVGHKTDTDRVAIARGSVRMNATAYGLLTQPGQGKGEVLNTARVAAVLAAKRCAELIPLCHSLPLAFVGIDFELDEAAHSVHIRATCRTQYKTGVEMEAMTACSVAALTIYDMCKAADKGIVIEQIRLQYKAGGKSGEWRND
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: RLMH_PSEPG
Sequence: MRLRLIAVGSRMPKWVEEGWHEYAKRLPTELSLELVEIPLNTRGKNADVARLIRQEGEAMLSKVQPGERIVTLEVHGKPWSTEQLATELDRWRLDARTVNLMVGGPEGLAPEVCARAEQRWSLSPLTLPHPLVRILIGEQIYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE_SYNS9
Sequence: MVRVRLAPSPTGTLHIGTARTAVFNWLYAKSQNGDFLLRIEDTDKERSKPEFTQNILEGLQWLGIDWAEDPVIQSERVAQHRDAIRALLEKGLAYRCYANESELATMRDAQKASNQPPRYDNRHRNLTKEQETAYQAEGRDAVIRFRIDDDADIHWNDLVRGTMRWRGGDLGGDMVVARRAPADQIGDPLYNLVVVVDDAAMEITHVIRGEDHIANTAKQLLLYEALGLPSPTFAHAPLILNADGKKLSKRDGVTSINEFRSMGYTAEAIANYMTLLGWSVPEGMEERFTLREAADQFSFDRVNKAGARFDWDKLNWLNAQVLHSWSSAQLLDVLRPLWLKNGWTIPNDNGWALELCELLGPSLTLLNDGLDQAAPFFECPDLEDDGLKQLQSEGAKAAISHLIDALQAERWMGTDFDQAQTLLGDAAKAAGVKKGVMMKSLRAALLGRLQGPDLLTTWSLLAKNSDDLPRLQRCLS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_DESVH
Sequence: MKIILRADVENLGRLGDVVTVKPGFGRNYLLPQGLGMLASQANLKAFELERKKLQARMDALRNAAADIAAKLEGLVLAIPMRVGENDKLYGSVTTAIIGDGLAAQGIEVDRRRILLDSAIRALGEYPVRVRLHADVTAEILVKVVSEDKVNDVAESAPAEEPEAAAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: YIQ4_SCHPO
Sequence: MDIGILSSLKPAQSFRDNSLGSFINSIDYSDSGEYVATTCSADDTVQIYDALDPKQVHTITCFETGIEVARFTHHDHNLLLSTTKGNKDIQYVSIYDNKRISYFSGHTDIVSSIEVSPIEDQFVSTANDKTLKLWKMNQSSRCLGNLDLPSLGIPAYDPTGLVFAVACHSLSRIFLYDVRNYGSDPFSTFTIDDSRYLSRFSFPPMMPEWKHMEFSNDGKCILLSTRANVHYILDAFSGDVLSRLEDFQELPFSNNFHGGSTTFVPQGNFVIGSADDRTLNVWNLRHTFHHKGKTRPPEHRIVSQSIINPGLVKYNPRYDQLLTAGSQLVFWLPEKYALTS
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C824.04.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RUVA_NEIMF
Sequence: MISRLTGKLVEKNPPQIVIDVNGVGYEADVSMQTFYNLPPVGESVQLFTQLIIREDAHLLFGFATAEERKTFRQLIKVSGIGAKTALGILSAMTADELAQAVAEEDVKRLSSAPGIGKKTAERMVLELRGKLVAHAVTDGLFAAAPAADETEDIVGTLLALGYSEREAKAAVKGVPKGTDVGEGVRLALKNLLK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RL3_DROME
Sequence: MSHRKFSAPRHGSMAFYPKKRSARHRGKVKAFPKDDASKPVHLTCFIGYKAGMTHIVREADRPGSKINKKEVVEAVTVLETPPMIVVGAVGYIETPFGLRALVNVWAQHLSEECRRRFYKNWYKSKKKAFTKASKKWTDDLGKKSIENDFRKMLRYCKVIRVIAHSQIRLIKQRQKKAHVMEIQLNGGSIEDKVKWAREHLEKPIQVSNVFGQDEMIDCVGVTKGKGFKGVTSRWHTKKLPRKTHKGLRKVACIGAWHPSRVSTTVARAGQKGYHHRTEINKKIYRIGAGIHTKDGKVIKNNASTEYDLTDKSITPMGGFPHYGEVNNDFVMIKGCCIGSKKRIITLRKSLLKHTKRSALEQIKLKFIDTSSKMGHGRFQTPADKLAFMGPLKKDRLKEEAAATTAAAAAATTTSA
What is the function of this protein?
The L3 protein is a component of the large subunit of cytoplasmic ribosomes.
What are the official names of this protein?
60S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I2B8_CONEM
Sequence: MMFRLTSVSCFLLVIACLNLFQVVLTSRCFPPGIYCTPYLPCCWGICCGTCRNVCHLRFGKRATFQE
What is the function of this protein?
Inhibits the vertebrate voltage-gated potassium channels Kv1. 1/KCNA1 and Kv1. 3/KCNA3.
What are the official names of this protein?
Kappa-conotoxin-like Em11.8.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I2 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: C125_CYPDO
Sequence: DTARLQWH
What are the official names of this protein?
Peptide Cd-125.
What are the subcellular locations of this protein?
Secreted.
Protein: MUC21_ARATH
Sequence: MRQNLKKVAQIKVDESKKLFPYVFRVKTSCGNCAKRSKPKLIYLLIFSLISSCFVFAPQLLCFPYPSALFLIDSSIKEIENRVSESNIESPKTSQKEESISCDRTGYRSDICFMKGDIRTHSPSSSIFLYTSNDLTTDQVLQEKIKPYTRKWETSIMETIPELKLVTKDMKLFGDKRKCEVIHEVPAVLFSTGGYTGNLYHEFNDGLIPLYITSKRFNKKVVFVIAEYHKWWEMKYGDVLSQLSDYSLIDFNKDKRTHCFKEAIVGLRIHGELTVDPSQMQDDGTTINEFRNVLDRAYRPRINRLDRLEEQRFHARLAQRRKAKRPKLALFSRTGSRGITNEDLMVKMAQRIGFDIEVLRPDRTTELAKIYRVLNSSKVMVGVHGAAMTHFLFMKPGSIFIQIIPLGTDWAAETYYGEPAKKLGLDYNGYKILPRESSLYEKYDKDDPILKDPNSITKKGWQFTKGIYLNDQKVRLDLHRFKKLLIDAYAKSIR
What is the function of this protein?
Glycosyletransferase required for the proper composition and structural properties of released seed coat mucilage (PubMed:11706181, PubMed:26482889, PubMed:26979331).  Required for the production of highly branched xylan polymers in seed coat mucilage (PubMed:26482889).  Facilitates the addition of xylose residues directly to the xylan backbone (PubMed:26482889, PubMed:26979331).  Xylan with xylose side chains seems to be necessary for pectin attachment to the seed surface (PubMed:26482889, PubMed:26979331).  Essential for xylan synthesis in seed coat epidermal (SCE) cells (PubMed:26482889).
What are the official names of this protein?
Xylan glycosyltransferase MUCI21, Protein MUCILAGE-MODIFIED 5, Protein MUCILAGE-RELATED 21, Putative xylan xylosyltransgerase MUCI21.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 61 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: RIBA_CITK8
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGQTPVLARVHSECLTGDALFSLRCDCGFQLEAALTHIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVDEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAAKMGHLLGK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: DAPF_PSEA7
Sequence: MLLRFTKMHGLGNDFMVLDLVSQHAHVQPKHVKLWGDRNTGVGFDQLLIVEAPSSPDVDFRYRIFNADGSEVEQCGNGARCFARFVQDKRLTVKKSIRVETKGGIIELNIRPDGQVTVDMGPPRLAPAEIPFQAEREALSYEIEVNGQRVELAAVSMGNPHGVLRVENVDSAPVHSLGPQLEVHPRFPKKANIGFLQVLDPHHARLRVWERGVGETQACGTGACAAAVAGIRQGWLQSPVQIDLPGGRLHIEWAGPGQPVMMTGPAVRVYEGQVRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_CORGB
Sequence: MTSNFSSTVAGLPRIGAKRELKFALEGYWNGSIEGRELAQTARQLVNTASDSLSGLDSVPFAGRSYYDAMLDTAAILGVLPERFDDIADHENDGLPLWIDRYFGAARGTETLPAQAMTKWFDTNYHYLVPELSADTRFVLDASALIEDLRCQQVRGVNARPVLVGPLTFLSLARTTDGSNPLDHLPALFEVYERLIKSFDTEWVQIDEPALVTDVAPEVLEQVRAGYTTLAKRGGVFVNTYFGSGDQALNTLAGIGLGAIGVDLVTHGVTELAAWKGEELLVAGIVDGRNIWRTDLCAALASLKRLAARGPIAVSTSCSLLHVPYTLEAENIEPEVRDWLAFGSEKITEVKLLADALAGNIDAAAFDAASAAIASRRTSPRTAPITQELPGRSRGSFNTRVTLQEKSLELPALPTTTIGSFPQTPSIRSARARLRKESITLEQYEEAMREEIDLVIAKQEELGLDVLVHGEPERNDMVQYFSELLDGFLSTANGWVQSYGSRCVRPPVLFGNVSRPAPMTVKWFQYAQSLTQKHVKGMLTGPVTILAWSFVRDDQPLATTADQVALALRDEINDLIEAGAKIIQVDEPAIRELLPLRDVDKPAYLQWSVDSFRLATAGAPDDVQIHTHMCYSEFNEVISSVIALDADVTTIEAARSDMQVLAALKSSGFELGVGPGVWDIHSPRVPSAQEVDGLLEAALQSVDPRQLWVNPDCGLKTRGWPEVEASLKVLVESAKQAREKIGATI
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: BACD2_CHICK
Sequence: MSGDTCLTTTLCPAVGPKPKTCSFKVGSLGNKYVRLNVGGSLYYTTVQVLTRHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTIALPKHRQEIKELMAEAKYYLIQGLVDMCQAALQDKKDLYEPVCNIPIITSPKEEERLIESSMKPVVKLLYNRSNNKYSYTSNSDDNLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEATSRSRSQASHSEDDDGFELRDRVRRIHVKRYSTYDDRQLGH
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure.  The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2, BTB/POZ domain-containing protein TNFAIP1.
What is the protein family that this protein belongs to?
Belongs to the BACURD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endosome.
Protein: COPB2_DICDI
Sequence: MPLRLDIKKKLSTRSDRVKSVDIHPTEPWILASLYDGNVYIWNYETQNMVKSFEVSPNNPVRTARFIAKKQWIVTGSDDTYIRVYNYNTMEKIKSFEAHADYIRCIIVHPTLPYILSSSDDMFIKLWDYEKGWSNTQVFEGHSHYVMSIAWNPKDTNQFATASLDKTVKVWSINSPHPHFTLEGHEKGINSVEYFSGGEKPYLISGADDKLVKIWDYQSKTCVQTLEGHSNNVSVVCYHPELPLILSGSEDGTVKLWHSSTYRLERTLNYGMGFVWSMNFLRGSNFIGLGYDDGTVVLKIGKNKPPVSMDQGGKVIYAKHNEIRISNISSTLEQEVQDGEKLSLQSKDLGNCEVFPQSLQHNSNGRFVSVCGDGEFIIYTALAWRNKSFGNALEFVWAEDSGQYAVRESTSRIKIFKNFKETHSFKPSFSAEGIFGGSLLGVKSNDTLCFYSWDSADIIRRIEKTSPKNIFWSENGDYLAIVTDKSTFILRYYKDTVQKYIESGQPIGELGIENAFDVVHEIEDTIGTGLWVGDCFIYINRSSKLNYCVGTEVVTISHLEKHMYLLKYLPQSGRLYLSDKNLNIVSYKLHISVISYQTSILRGDLEGAERILPKIPQDQRNSIAHFLESQGYKEKALEVSTDLDHRFELAIQLENLDVAHEIALKSDSETKFKHLGDLALSIGEIKLAENCLKKAEDLPGLLLLYTSTGDIEGMKMLAKLSEEKGQTNISFICNLLLPNSLLNCLNTLCASGDYSEAAFMARTYLPSMVPDMVEKWKESLKSTSSKASDALSNPIDFPNLFPQYDLSIKAEKYFESLRSQPKSSFDYLKNATAQSLSKKQRNLLEEIESVSQQDYDKVLSQLQHFSLHSGISDITTTTTNTNNNTNNTNNNNTASLLDDLDFTSTTTTTTTTTNTNTTQKVASPLSSPSPIRKNDSIASPQKQQQQQQDINITAPPLIDPSPVDHDLVLEPTPIINTVSPTKTSPTADLSFLDNIPVDHDEEDEF
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit beta', Beta'-coat protein, Beta'-COP.
What is the protein family that this protein belongs to?
Belongs to the WD repeat COPB2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: SURE_THIDA
Sequence: MRILLSNDDGYFAPGLAALAEALAPLAEVTVVAPERDRSGASNSLTLDRPLMLRQAPSGFYYVNGTPTDCVHLAVTGMLDHLPDMVISGINHGANMGDDTIYSGTVAAATEGYLLGIPSIAVSLANHNALYFDTAARVVSDLVRRLQNNPPTEPTLLNVNVPDRAWDAVRGISVTRLGKRHKAESVVKTSNPRGQTVYWVGAAGAAQDAGEGTDFHAVANGYVSITPLQMDLTRFSQMESVTAWLKP
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAE1B_THEVO
Sequence: MIVLGLEGTAHTISCGILDENSIMANVSSMYKPKTGGIHPTQAAAHHVDKVSEVIAKAIEIAGIKPSDIDLVAFSMGPGLGPSLRVTSTAARTLAVTLKRPIIGVNHPLGHIEIGKRLSGAQDPVMLYVSGGNTQVIAHLNGRYRVLGETLDIGIGNMIDKFARYAGIPFPGGPEIEKLAKDGRKLLTLPYSVKGMDTSFSGILTSALEYLKKGEPVEDISFSIQETAFSMLVEVLERALYVSGKDEVLMAGGVALNNRLREMVSEMGREVDATTYMTDKNYCMDNGAMIAQAGLLMYKSGIRMNIEDTSINPRYRIDEVDAPWVIEKNVKYRDAGAESRIVNTDFYGRSAVKKIRIAKGYRLKELDERIRGERMKNEFTVIRRMRDAGICVPIVYDYDPFEKTLTLSQIQGELLRDVIRARPNVMGNVGHDVAVMHKNKISHGDLTVNNIIVSDRICFIDASMGKVNAELEDLAVDVYTLEDSINSLSENGKTLMKEFKMSYRANFPQANDVLNIVEDIRRRHRYV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  The Kae1 domain likely plays a direct catalytic role in this reaction.  The Bud32 domain probably displays kinase activity that regulates Kae1 function.
What are the official names of this protein?
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the protein kinase superfamily. Tyr protein kinase family. BUD32 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_PSYCK
Sequence: MSKTTFDAQSITNSLRAAKHQPRKRFGQNFLHDRSVIREIVESIRLERDDNLIEIGPGMGALTEPLLAEVDAMTVVELDRDLADSLRIRIGANSHPNFEIIKNNAMHVDYRELYSDERGKLRVVGNLPYNISTPILFHLLSYADVIEDMHFMLQKEVVERITADVGSKTYGRLSVIMQYHCHTDYLLTVPRGAFNPPPKVTSAVFRLTPHIIKPVVAEDEEYFALVVRETFNHRRKTLRAIFKKSTLLPTLSEDDFAACAIDPQARPETLSVKDFVNLSNQARKVEG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRHO_RICCK
Sequence: MNEKIAILSTYSFVNIEEPANLIPKLLLIAKRKYVRGTILLSKEGFNGSFSGSYENVNLVLEELIKLTVPKDVNVKINYSDLHPFQKLKVRLKKEIVAMNVDDLNVDLFKGEYIESKDWDSFITKQDVIVIDTRNDYEVEIGTFKSAINPYTKTFKQFPAWVHQNEKLLKGKKIAMFCTGGIRCEKSTSLLKSIGYDDVYHLKGGILQYLEDTQNKNNLWQGECFVFDDRRAVEDDLSPSERHTRLPST
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: PSUG_LYSSC
Sequence: MKEFIVLSEEVKAGQAKGLPIVALESTIISHGMPYPQNVQTAREVEQIIRDNGAVPATIALIDGKIKIGLSDEELEMFGNAQGVAKASRRDLGYLLATKKLGATTVAATMICAELAGIEIFVTGGIGGVHRGAETTMDVSADLEELAQTNVAVICAGAKSILDIGLTLEYLETKGVPVVGYGTDELPAFYTRQSGFDVNFQLDTPEEIAEMLSAKWQLGLKGGAVIANPIPEAEALEHGFITNIIEKALVEAEENGIQGKNVTPFLLGKVKELTEGKSLDANIALVKNNAVVGAKIAVAFNQLH
What is the function of this protein?
Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil.  Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.
What are the official names of this protein?
Pseudouridine-5'-phosphate glycosidase, PsiMP glycosidase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine-5'-phosphate glycosidase family.
Protein: SECA_BIFLS
Sequence: MVDIVDKALRMGEGHQLKKLENVAKAVNALEDEISALSDEDLKAQTPKFKQEIENGKSLDEIMPEAFATVREVSKRTLGQRHFDVQLMGGAALHWGNIAEMKTGEGKTLVATLPTYLNALEGKGVHVVTVNDYLASYQSELMGRIYRFLGMNVGCIITEQKPPERRKQYNADITYGTNNEFGFDYLRDNMAWEKADLVQRGHHYAIVDEVDSILIDEARTPLIISGPAEGDVTRWYRQFAKLVLKLTRDEDYDVDEKKKVVGILDPGITKVEDFLGIDNLYEPANTALIGYLNNAIKAKELFLRDKDYVVTQGEVLIVDEHTGRILPGRRYNEGLHQAIEAKEGVEVKAENQTFATITLQNYFRMYDKLAGMTGTAETEAAEFMNTYKLGVLPIKTNKPMIRKDQDDLIYRTKKEKLAAIVKDVAKRHAEGQPVLLGTASVESSEVVSALLDVAKIPHQVLNAKQHEKEAAVVAVAGRKGAVTVATNMAGRGTDIMLGGNVEFLADAKLKSEGYSPEDTPEEYEKRWPGTLNEIKAQVKDEHEEVKELGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLEDDLMRLFNTQLVAQVMARGMEEGQPIEAKSVTKGVRTAQKAVESRNYEIRKNVLKYDDVMNKQRTVIYSERQAVLKGEDIHKDILRFISDTVESYIKGANKGSEKPKDWDWEGLFKALNTVIPTKVDEDEVRKIVGGLKGAKAVEAVRDLIVEDARQQYGEMEETIGETGLRDLERRVVLAVLDRKWREHLYEMDYLKDGIGLRGMGQRDPLVEYQREGYQMYNSMIEAIKEETVQLLFHIDIKQVATTDDAVDEVEETAESADTIAVASGPDENGESVVEAAEGEVEEEDEDTDAKQAIAESAAASEAGESTLPVAGPAPVSHAEGKVPVSKRPKSEELKTPWADGRTFPGTGKNAPCPCGSGRKYKMCHGQNEA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: YK018_YEAST
Sequence: MLGMIRWVVEGTLVAMLLSAIRRETGMIFFYNQYQLGGWIHRYLSWGEMCYTRTLKMVKRSKFFRKQLNEDGFGRINDSGPKRRGRDQSQYSSRFVELD
What are the official names of this protein?
Uncharacterized protein YKL018C-A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_JANSC
Sequence: MTKRTSAKYKIDRRMGENIWGRPKSPVNRREYGPGQHGQRRKGKLSDFGLQLRAKQKLKGYYGDLTEKQFRRIYAEAERLRGDTGEFLIGLLERRLDAVVYRAKFVPTVFAARQFVNHGHVTVNGQKVNIPSYRVKEGDVIAVRDKSKQLAVVLEAVGLAERDVPDYVDADHSKMTATFVRTPGLSDVPYPVVMEPNLVVEFYAKN
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.