PharMolix/UniProtQA huggingface dataset:
Protein: LIPA_BURM9
Sequence: MTDLTATPAPAEPAASAYDPTAKQKAQAKTARIPIKIVPIEKLKKPEWIRVKAATSSSRFNEIKTILREHNLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDADEPKNLARTIAALKLKYVVITSVDRDDLRDGGAGHFVECIREVREQSPATRIEILTPDFRGRLDRALAILNAAPPDVMNHNLETVPRLYKEARPGSDYAHSLKLLKDFKALHPDVATKSGLMVGLGETTDEILQVMRDLRAHDVDMLTIGQYLQPSEHHLPVREYVHPDTFKMYEEEAYKMGFTHAAVGAMVRSSYHADLQAHGAGVV
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP6_CHRVO
Sequence: MASNATDYIKHHLTFWNSDPSAGFWSLHVDTFSISLVLGFLFAAVFAMVARRASIEAPGRLQLFVEMIVELVQTQVREVFHGKSKMIAPLALTIFCWVFLMNFMDLFPVDLFPMAAQWIGYTFFGLEPHHVYFRVVPSADVNATFAMSLSVLILIVGFSIKAKGLGGWGKELLTAPFHSSNPVGAIILAPLNFAFQLVELAAKPISLSLRLFGNLYAGELIFILIALLPWGLQWVLGAPWAIFHILIITLQAFVFMMLTIVYLSLAVEAH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LUXS_STRPG
Sequence: MTKEVIVESFELDHTIVKAPYVRLISEEFGPKGDRITNFDVRLVQPNQNSIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVIKSSLEEIATGITWEDVPGTTLESCGNYKDHSLFAAKEWAQLIIDQGISDDPFSRHVI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: Y410_SYNY3
Sequence: MSDSPKPQLPPSPQGDHCLVHQQELEAVTEKWFEIMVRVQPHHTDYGGVVWHGTYLTWLETARVECLRSIGVDFADLVKLGCDLPVVSLALRYHRAIRLGQTAVIKVQMQEIQKVRLEWQNQIVCLETGEPCVTGKITLVAIDPAKGKIMRRLPPVVQEHLLKLRQ
What are the official names of this protein?
Putative esterase sll0410.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
Protein: AGO_GIAIB
Sequence: MTTDIVTSRINFYPYTVLPSAKPVYQYDLSIQVSTQGYNLDNADSYRALEKFCEQQDTALGNDPARSLFYSLIVDFPSSDSRPISSFYSQTDLGSRPVTHTVEFLSTQKPKRRGGRAGGMRGNRGGPSTTSVQALVKVTRVRQMDPLDLMSMKTLLNILLRRTFESSLGMLNIRSGFYDLNRTSTHNIQVDGRGFDICWIPGFRLTTATLYGKLGLQVLPETTKVRSKSMCELLNENRGSLHPNALAAITVMAMHNGRVFRIHSIVRGQSVVSPLAEGSDTDYFTYYSAKYKDKIDSAALSLLKQDDYCNSVLQRDKFILKLTPLKKTHNGKVVRSCNVPSSLCIIISDNEIAPYGVSKLSTNKTAVALSTMSPDALLEKATEFANQLIDNAELQSVLGDYGFRFTSQPLELDTFVCKPPKLMMDTLSRELTVEDDSGGVFRSLIQSPGVSSIYYANNGQPAVGMPHWALMVPRYLKNDYARRLKQELTQRIRSLAGATASTVEEPLLIAVDVNEQRRDMYRIEPYKDAFESLLVKLNTQYPDTKNSELISRIQLVVVVIPGPKQYSGGLYKEVKRFYTDKGIVTQCLLTPRLSRDGPEWYDQAILNGLCQQIYAKAGGAVWAPALPKDNAYSTSTMLCALDVSRPKKTVGRPTEVPASTAGFISTYEGSFEYIYSQKKNLMPNRLNQGGEVQQQTLMKTFIKNSCEVYSAFNSSLPDRIVIFRDGVSDGQISTVLETEINSLYEYLCQRYREANRPMCDLKVIVAQKTCAMRLAAVSNTDLRPGFYILNHSPDNKQKGSEFIMASQAIVHGTTPKPIRYKLIFDSTEASMDNSSFKQLIELTNTMAYGYVNWPQAISLPHILHMAHLLSKFCGEILGNGRDLLESQAIFGLQYRPFFI
What is the function of this protein?
Plays an essential role in growth and, with Dicer, also involved in microRNA (miRNA)-mediated translational repression.  The RNA interference pathway is implicated in antigenic variation having a role in regulation of variant-specific surface protein (VSP)-coding gene expression.  Several VSP genes are transcribed but only transcripts encoding the VSP to be expressed accumulate.  Antisense RNAs corresponding to the silenced VSP genes are detected (By similarity).
What are the official names of this protein?
Protein argonaute.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_PSEMY
Sequence: MSETDEVVIYTDGACKGNPGPGGWGALLVYKGVEKELWGGDPSTTNNRMELMAAIAGLIALTRPCSVKLVTDSQYVMKGIQEWLPNWKKRGWKTASKEPVKNADLWQKLDEEVNRHQVSWQWVRGHTGHPGNERADQLANRGVDEVRSAR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBS_NICPL
Sequence: MASSVLSSAAVATRSNVAQANMVAPFTGLKSAASFPVSRKQNLDITSIASNGGRVQCMQVWPPINKKKYETLSYLPDLSQEQLLSEIEYLLKSGWVPCLEFETERGFVYREHHHSPGYYDGRYWTMWKLPMFGCTDATQVLAEVEEAKKAYPQAWVRIIGFDNVRQVQCISFIAYKPEGY
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic, RuBisCO small subunit, Ribulose bisphosphate carboxylase small chain 8B, chloroplastic, RuBisCO small subunit 8B.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IPYR_PICPA
Sequence: MSYSTRQIGAANTLENRVFIEKDGQVVSPFHDIPLYADESKKVLNMVVEVPRWTNAKLEISKEEKLNPILQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTWEDPNVTHPETKAKGDNDPLDVCEIGERSYTGQVKQVKVLGVMALLDEGETDWKVIVIDINDPLAPKLNDIEDVEKHMPGLLRATNEWFRIYKIPDGKPENQFAFSGECKNKKYAEEVIQECREAWEKLIFGKTSPGEIDLTNTTLQSTPSFSPSATSAVPTASPAAPAKIDQSIDKWFYISGSA
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_XANAC
Sequence: MTKGPVRLDVAVSYALPRAGLPSAVSFRKWVAAALKGRIREADLAVRVVDEKEGCSLNHHYRGKDYATNVLSFPAELPEGLPKGIKMPLLGDLVICAPVVAREAAEQGKSLAAHYAHLTVHGTLHLLGWDHEDDKEAEAMEQLEREILADLGIDDPYAGEH
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_PYRCJ
Sequence: MSLASRRKVRIRLYGTNPADLDQVAREIVDLAKKMGVAVRGPIPLPTKRLMVTVRRAPSGQGYHTFDHWELRISKRLIDIEASERVLRRLMTIRVPDTVKIELQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: ZBP1_HUMAN
Sequence: MAQAPADPGREGHLEQRILQVLTEAGSPVKLAQLVKECQAPKRELNQVLYRMKKELKVSLTSPATWCLGGTDPEGEGPAELALSSPAERPQQHAATIPETPGPQFSQQREEDIYRFLKDNGPQRALVIAQALGMRTAKDVNRDLYRMKSRHLLDMDEQSKAWTIYRPEDSGRRAKSASIIYQHNPINMICQNGPNSWISIANSEAIQIGHGNIITRQTVSREDGSAGPRHLPSMAPGDSSTWGTLVDPWGPQDIHMEQSILRRVQLGHSNEMRLHGVPSEGPAHIPPGSPPVSATAAGPEASFEARIPSPGTHPEGEAAQRIHMKSCFLEDATIGNSNKMSISPGVAGPGGVAGSGEGEPGEDAGRRPADTQSRSHFPRDIGQPITPSHSKLTPKLETMTLGNRSHKAAEGSHYVDEASHEGSWWGGGI
What is the function of this protein?
(Microbial infection) In case of herpes simplex virus 1/HHV-1 infection, forms hetero-amyloid structures with HHV-1 protein RIR1/ICP6 which may inhibit ZBP1-mediated necroptosis, thereby preventing host cell death pathway and allowing viral evasion.
What are the official names of this protein?
Z-DNA-binding protein 1, DNA-dependent activator of IFN-regulatory factors, DAI, Tumor stroma and activated macrophage protein DLM-1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic (PubMed:16876127, PubMed:16990255). Accumulates in the nucleus in response to influenza A virus (IAV) infection: senses IAV defective viral genomes RNA in the nucleus (By similarity). SUBCELLULAR LOCATION: [Isoform 7]: Cytoplasm. Nucleus. Note=Compared to isoform 1, a higher proportion of this isoform is localized in the nucleus.
Protein: MAA_ECOLI
Sequence: MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHTLRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCMLAPGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGAVVTKDVPDNVVVGGNPARIIKKL
What is the function of this protein?
Catalyzes the CoA-dependent transfer of an acetyl group to maltose and other sugars (PubMed:1856235).  Acetylates glucose exclusively at the C6 position and maltose at the C6 position of the non-reducing end glucosyl moiety.  Is able to acetylate maltooligosaccharides (PubMed:12731863).
What are the official names of this protein?
Maltose O-acetyltransferase, MAT, Maltose transacetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: SYC_ERWT9
Sequence: MLKIYNTLSRQKEEFKPIHAGKIGMYVCGITVYDLCHIGHGRTFAAFDVVARYLRYSGYQLKYVRNITDIDDKIIKRAQENGESIEQLTNRMIGEMHKDFAALNILPPDLEPRATRHITEIVELVEKLIAREHAYVASNGDVMFSVDSDPQYGSLSRQDLDQLQAGARVEVAADVKRNPMDFVLWKMSKADEPGWASPWGNGRPGWHIECSAMNCKQLGEHFDIHGGGSDLMFPHHENEIAQSTCAHDGPYVNYWMHSGMVMIDREKMSKSLNNFFTVRDVLEHYDAETVRYFLMSGHYRSQLNYGEDNLNQARSALERLYIALRNTDTGATPAGGEEFETRFREAMDDDFNTPEAYSALFDLAREVNRMKAEAPAAADGLAARLRVLGGVLGLLEQDPEQFLQSGANSNDEEVAQIEALIQMRIDARNEKNWAQADVARDRLNEMGIVLEDGAGGTRWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBM18_PONAB
Sequence: MEAETKTLPLENASILSEGSLQEGHRLWIGNLDPKITEYHLLKLLQKFGKVKQFDFLFHKSGALEGQPRGYCFVNFETKQEAEQAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNDKILPISLEPSSSTEPTQSNLSVTAKIKAIEAKLKMMAENPDAEYPAAPVYSYFKPPDKKRTTPYSRTAWKSRR
What are the official names of this protein?
Probable RNA-binding protein 18, RNA-binding motif protein 18.
Protein: SPEE_CLOBA
Sequence: MELWYTEKHTEDVKFSIRVDRELYTEQSKFQRIDILESKEFGRFFTLDGLMMVTEKDEFIYHDMIVHVPMATNPNIKKVLVIGAGDGGTIRELTRYKTIEKIDMVEIDESVVEACKKYLPKTACKLEEERVNIVYEDGLKFVRNKENDYDLIIVDSTDPFGPGEGLFTKEFYGNCYKALSEDGILVNQHESPYYEYYAKSMKDAHEKIQGLFKINKVYQAHIPTYPSGHWLFGFASKKYDPIKDLNVEAWKSLGIQTKYYNTDLHVGCFALPTYVIDMLNEDKE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_STRMU
Sequence: MKLHELKPAQGSRKTRNRVGRGSSSGNGKTAGRGQKGQKARSGGNIRSGFEGGQTPLFRRLPKRGFTNINAKEYALVNLDQLNVFEDGAEVTPVVLVETGIVKAEKSGIKILGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: PVK21_NEORO
Sequence: GSSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.1, Pea-PVK-2-like peptide, Periviscerokinin-3, NeoRh-PVK-3.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: S1PR2_MOUSE
Sequence: MGGLYSEYLNPEKVLEHYNYTKETLDMQETTSRKVASAFIIILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGHVTLSLTPVQWFAREGSAFITLSASVFSLLAIAIERQVALAKVKLYGSDKSCRMLMLIGASWLISLILGGLPILGWNCLNQLEACSTVLPLYAKHYVLCVVTIFSVILLAIVALYVRIYFVVRSSHADVAGPQTLALLKTVTIVLGVFIICWLPAFSILLLDSTCPVRACPVLYKAHYFFAFATLNSLLNPVIYTWRSRDLRREVLRPLQCWRRGKGVTGRRGGNPGHRLLPLRSSSSLERGMHMPTSPTFLEGNTVV
What is the function of this protein?
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (By similarity).  S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues (By similarity).  Receptor for the chemokine-like protein FAM19A5 (By similarity).  Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).
What are the official names of this protein?
Sphingosine 1-phosphate receptor 2, S1P receptor 2, S1P2, Endothelial differentiation G-protein coupled receptor 5, Lysophospholipid receptor B2, Sphingosine 1-phosphate receptor Edg-5, S1P receptor Edg-5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSPC_PENSO
Sequence: MAYTLTSIVLGVVVFGLTRIIWGSISWNLRYRRFHSSDGCQQLRSAPSKDPILGLDHFFRLGKAAHNSRYLEAFQEWFQAVGSTFGVNLMGDYVIFTNEPKNVQAVLVTKFKDFEIGQRRRDNSAELLGIGVFNADGQTWEHGRALVRPNFTRKQVADLGLFEKHVQRLFEALPKDGTAVDIQEWTLDTGTDVLFSESSDVLLPSATEVARKFAWAFNRGIDGIAQRIRLGRFARFYYDPQYTAACKFVHDYVDEIVAKAVYRAKEWHAEKKDKPVPPDDAEEERYTFLNALAREGVEPKQIRDQILNILVAARDTSACLMSAAVFELARRPEYQVQLRREIAEKLSGRQPTFEDLKDLTFLNHFVKETLRMYPPVPLNARVAKNDTVLPRGGGSDGMAPIFVPRGQLVVYQVYSMHRREDLWGSDAHIFRPQRWETTRPTFEYLPFNAGPRICPGQQFALVETSYVLVRLLQEYSNIEARGNSAPWREHLTLTCSVGQGVWVS
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the alkylresorcinols called soppilines (PubMed:31086874).  The biosynthesis starts with the HR-PKS pspA-catalyzed carbon chain assembly through nine chain elongation cycles, using acetyl CoA and malonyl CoA as a starter and extender units, respectively, to produce the polyketide soppiline A (PubMed:31086874).  In the first round, the KR, DH, and CMeT domains work to produce 2-methyl-2-butenyl thioester (PubMed:31086874).  In rounds 2 to 5, the KR, DH, and ER domains fully catalyze the reduction of the elongated beta-ketothioester, resulting in the insertion of eight methylene units (PubMed:31086874).  The unusual Z,E,Z-triene motif is likely constructed during rounds 6 to 8 (PubMed:31086874).  Typically, the DH domain introduces a double bond at an alpha,beta-position of an elongated polyketide chain, with the dehydration of a beta-hydroxy group (PubMed:31086874).  The last extension cycle would be carried out with L-oriented beta-ketoreduction by the KR domain to produce beta-hydroxy carboxylic acid soppiline A (PubMed:31086874).  The type III PKS pspB intercepts the elongated polyketide chain at round 8 from the HR-PKS pspA, followed by a tri-keto extension and decarboxylative aldol cyclization to produce 1,3,5-trisubstituted alkylresorcinol soppiline B (PubMed:31086874).  Subsequently, the cytochrome P450 monooxygenase pspC catalyzes three-step oxidations at the C-4 methyl group to carboxylic acid to yield soppiline C (PubMed:31086874).
What are the official names of this protein?
Cytochrome P450 monooxygenase pspC, Soppiline biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FOLD2_NOCSJ
Sequence: MTAQKLDGTATAAAIKGELTTRVAALHERGIRPGLGTILVGDDPGSRWYVNGKHKDCAEVGIESIRIDLPATATQDEIEDAVRVLNDDPACTGYIVQLPLPKGRDENRVLGLIDPAKDADGLHPTNLGWLVLGKAAPLPCTPNGIVELLRRHGVEIAGAEVTVVGRGVTVGRPLGLLLTRRSENATVTLCHTGTRDLAAHVRGADIVVAAAGVPGIVTGAMVKPGAAVLDVGVSRVDGKLAGDVAPEVWDVARWVSPNPGGVGPMTRAMLLSNIVAMAEQTDS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DDAH2_RAT
Sequence: MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEMGDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGASHLRGLCGMGGPRTVVAGSSEAAQKAVRAMAALTDHPYASLTLPDDAASDCLFLRPGLPGTTPFLLHRGGGDLPNSQEALQKLSDVTLVPVSCSELEKVGAGLSSLCLVLSTRPHC
What is the function of this protein?
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS.  Has therefore a role in the regulation of nitric oxide generation (By similarity).
What are the official names of this protein?
N(G),N(G)-dimethylarginine dimethylaminohydrolase 2, DDAH-2, Dimethylarginine dimethylaminohydrolase 2, DDAHII, Dimethylargininase-2.
What is the protein family that this protein belongs to?
Belongs to the DDAH family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Translocates from cytosol to mitochondrion upon IL- 1beta stimulation in chondrocytes.
Protein: MINC_ECOSM
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGKEKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARLQLVENALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: UP06_DAUCA
Sequence: YGLAADHVLDAR
What are the official names of this protein?
Unknown protein 6.
Protein: FHAE_BORPE
Sequence: MSQIFADRRAAVPARVISFCGAALAVWAGLAVQPAMAVDPPVDCGRALGLHFWSSASLISDQTPDGTLIGKPVVGRSLLSKSCKVPDDIKEDLSDNHDGEPVDIVLELGSNYKIRPQSYGHPGIVVDLPFGSTEETGIAIYIDFGSSPMQKVGERQWLYPQKGEVLFDVLTINGDNAEVRYQAIKVGPLKRPRKLVLSQFPNLFTYKWVFMRGTSQERVLAQGTIDTDVATSTIDLKTCRYTSQTVSLPIIQRSALTGVGTTLGMTDFQMPFWCYGWPKVSVYMSATKTQTGVDGVALPATGQAAGMASGVGVQLINGKTQQPVKLGLQGKIALPEAQQTESATFSLPMKAQYYQTSTSTSAGKLSVTYAVTLNYD
What are the official names of this protein?
Protein FhaE.
Protein: Y5092_PSEPW
Sequence: MLSWAITFLIIAIVAAVLGFGGIAGAATGIAKILFIVFLVLFVASFFFGRGRG
What are the official names of this protein?
UPF0391 membrane protein PputW619_5092.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSX_THEVB
Sequence: MQPMTRARIAVDAMGGDYAPDEIVAGALRASEELDADILLVGNPVPIQRYLDEHAPTAKPQIVAANDVVDMGEEPLSALKRKPKASINVAMDLVKAGAADAVVSAGHSGAAMAAALLRLGRLPGIDRPAIGAVLPTLLPGKSVLVLDVGANVDCRPKYLEQFAVMGSIYSQYVLDVENPKVGLLNIGEEDCKGNDLALKAHQLLRQNRQISFLGNAEGRDVLSGQFDVVVCDGFVGNVLLKFAESLGSVLVQILREELPRGWRGQLGTALLRPNLRKIKQRIDHAEHGGGLLLGVDGICIISHGSSQAPSIFNAIRLAKEAVDHRVSERIQACYQDAVAVEDQA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PURL_STRAW
Sequence: MSRTPLDTVEHAAATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCSYKSSKVHLRQFGEKAPQSDALLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGEVVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNKVILYGARTGGDGIGGASILASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLAICEKWDVIATVIGEVTDGDRLEIYWHGGKIVDVDPRTVAHDGPVYERPYARPEWQDALQADDANKLPRPSSSEELRDQVLKLVASPNQASKSWITSQYDHFVQGNTVLAQPEDSGMIRIDAESGLGVAIATDGNGRYAKLDPYAGAQLALSEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAIRGLADACQQLGTPVTGGNVSLYNQTGEVAIHPTPVVAVLGVIDDVARRTPVAFQEEGQLLYLLGDTREEFGGSAWSQVVHDHLGGLPPQVDLERERLLGEILISASRDGMIDAAHDLSDGGLIQAVVESALLGGKGARLVVPDGLDAFTFLFSESAGRAVVAVPRSEELRFNDMCGARGLPVTRIGVVDGDSVEVQGEFTLPLAELRKAHEETIPALLA
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_MANSM
Sequence: MKQKIVLATGNKGKVREMSDVLADFGFEVVAQTDLDIESPEETGLTFVENALLKARYAAKVSGLPAIADDSGLVVEALNGAPGLYSARYAGIDGETADAENRRKLLRDLADVPVGKRQAKFVSCIVMLRHETDPSPIIAEGECIGEIIFAEKGENGFGYDSLFFTPEKGCTFAELETVEKKKISHRARALAVLKSKLGA
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: Y1415_PELTS
Sequence: MKVTFLGHAGFLIEGSKKIVIDPFLTGNPLAKAKAEEVKADLVLVSHGHGDHLGDAVAIAGQSNALVVSVYELADYCARHGAQSHGMHIGGSRAFDGVKIKLTPAWHGAGFGTGEGPMEYLGNPCGFVIKIDGKTIYHSGDTGLFGDMELIGRFNSLDLALLPIGDNFTMGPEDALEAVKMLKPKTVIPMHYNTWPLIEQDPAEFKSAVEAATSAEVKILSPGESMEL
What are the official names of this protein?
UPF0173 metal-dependent hydrolase PTH_1415.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.