PharMolix/UniProtQA huggingface dataset:
Protein: PURA_PSELT
Sequence: MLKAAVIGLQWGDEGKGKVVTYLSRRYDCVVRYSGGSNAGHTVDYGNFKMVHHLLPSADIKKQKMMYIGPGVVVDLDVLLEEIDQINNLIPESRSLLRISKQAHVVIPIYRDLDEKIDSSRANQIGTTRRGIGISYANRAMRCGLRLEDFETPARAESFLNEISRTWSIKFDVKMILDSLIEKYNKIRDLLIDSSEAVRVLKEKDLLFEGTQGVLLDVDMGTYPYVTSTNCSTTGIQPGFGYPVQVDKIFGVMKAYTTRVGEGPFPTELKDEVGENLRRLGSEYGATTRRPRRCGWLDLVLIKYAIETSACNALIMTKADILSGFEKIPICMGYKIGGKFYTQINNTAHLTEIEPVYEEIKGWKSLHSKEFDDFIYKIERELGLKFAYISTGPKIEEITEL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_BACVZ
Sequence: MITKRIIPCLDVKEGRVVKGIQFLGLKDAGDPVELAEAYDRESADELVFLDISASHEGRKTMTDVVEQVAAKLAIPFTVGGGINQLSDMKRMLRAGADKVSVNTAAVLRPELITEGADFFGSQCIVAAIDAKYDEDSDCYKVYTHGGRQKTEWEVTAWAKEAVSRGAGEILLTSMDADGEKTGFNHTLTQLVTRAVPVPVIASGGAGSARHMLEAFTIGEADAALAASIFHYKETSIKEVKDYMKKHGVNVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KU80_PHANO
Sequence: MAAIRLISIGLWSMFGIRLPTQVATGRKSALMSVIGCRTDETDLGGVMEEAEGYENLRVFSELKQFLLGDIRTLQDQLRPSKTNDGDLLSALALAVQMIDGATQGKGGKPLKYDRRIIIVTDGRGSIDTDDLEQIAAKIRDPEAPVDLVLLGVDFDDPDNGFKEEDKSSQKAKNEVSLKGFVEDCNGVFGTLAEAIDQLQIPRLKETRPVPSFKGQLTLGDPGHYDATLTIDVERYPCTMLAKPPTASSFATRTDFGAGSAAGPSDESSHTMTGEEQPMTDLSAVRNQRVYQVDNEEEPGMKKNVEMDELERGYEYGRTAVHISESDMNVVKLETTPMLSLIGFVKAEAFERYLPLSRSNFLVPQRGNQAAQLSLSSFIHALYEADCYAVARLVTKELKPPVIVLLVPRIEVEWEALVDVELPFEEDMRRYKFPPLDRKLTISGKVITEHKDLPTDELTDAMSKYVDAMDLSTFGRDEDGNPAEYAKPEDTFSPIVHRIGHIIRWRATHPDPSLPMPPPSDILTKYANPPADLLDASTSQFEALKKAARVSKVPPKVKGRGKRNRAERDKPISGLDIDALLGNPNRVKIDPSNLVPSFKNALAASDDLETIKEAAQSMSTEIRSLIRSSVGDSGYGRALEALRVMRDELTELEEPEIWNEFIRGLKSDLLEGKLNGNRKDMWWKIRGNRYGLVDRKRSFVSDVTEEEASAFYNVA
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 2, ATP-dependent DNA helicase II subunit Ku80.
What is the protein family that this protein belongs to?
Belongs to the ku80 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: PYRG_OCEIH
Sequence: MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLSVTIQKFDPYINVDPGTMSPYQHGEVFVTQDGAETDLDLGHYERFIDINLNKYSNITTGKVYSSVIRKERRGDYLGGTVQVIPHITNEIKDQVFRAGEATGADVVITEIGGTVGDIESLPFLEAIRQIKSDVGRDSVMYVHCTLVPYIKAAGEMKTKPTQHSVKELRSLGIQPDAIVLRTEMAISKDMKEKIALFCDIDDKSVIEMRDADTLYQVPIALQEEKLDQITCNHFGLDCPEADMEEWKGLVNKVRNLSKTTHIGLVGKYVELPDAYLSVVESLKHAGYDYDTDVKIHWINSELLSEEQIKEELSKVDGVLVPGGFGDRGIDGKIEAIRYARENNIPFFGICLGMQLASVEFARNVVGLSQAHSAEINPHTPHPVIDLLPEQKDIEDLGGTLRLGAYPCKLVDGTKAKEAYDGADVIEERHRHRYEFNNVYRDQMAEKGFVFSGTSPDGRLVETIEVKDHPWFVACQFHPEFTSRPTRAQSLFKGFIGASVDYRKG
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: UBIA_HALHL
Sequence: MRTYAQLARLDRPIGNFLLLWPVLWALWIAAAGVPDLDLLVIFTLGVVVMRAAGCVINDFADRHIDGHVKRTRQRPFATGRVSEREALLLFVVLCLLAFGLVLLTNPLTILMSLVAVVLAATYPFTKRYTHLPQVHLGLAFGWAVPMVFAAQTGTVPVVAWLLLIATVLWATVYDTMYAMVDRDDDIKIGVKSTAVLFGDLDRLMIAILQGLMLLAMVQVGLHVEASTAYYLGLAGAAGLFAYQQYLIRRRERQDCFRAFLNNAWLGGVVFAGLAADLHL
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROQ_NOSS1
Sequence: MQPLSILVLHGPNLNLLGKREPGVYGSTTLAEINSLLAEAALKLQAKVFPLQSNHEGVLVDAIHEALGKHQGILINAGAYTHTSVALRDAIAAVNLPTVEVHLSNIYRREDFRHHSYIAPVVIGQISGFGVQSYLLGLQGLVAHLKG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: SYFA_FLAPJ
Sequence: MTDKIKEYIAEAKAFSTQNKEKLEEFRIKFLGSKGLVKDIFAEFKNVPNDQKKEFGQVINLLKTIAEEKVKTITEELESKEEIKSLYGDLSRPSEHIKIGSRHPISLIKNQIIDIFSNIGFNVSEGPEIEDDWHNFTALNLPEYHPARDMQDTFFIQTNPDILLRTHTSSVQVRYMENNKPPIRTISPGRVFRNEAVSSRSHCIFHQVEGLYIDKDVSFADMKQTLLYFTKEMFGKSKIRLRPSYFPFTEPSAEIDIYWGLKTETDYRITKGTGWLEIGGCGMVDPNVLKNCGIEPDQFNGFAFGMGIERIAMLIYQIGDIRMFYENDIRFLEQFKSTI
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY_SHIF8
Sequence: MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPISWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KAD_ACIB5
Sequence: MRIILLGPPGAGKGTQAQLICKRYNIPQISTGDMLRAAIREGTELGLKAKSVMESGGLVSDELIIGLVKERIAQPDCVNGCIFDGFPRTIPQAEALEKEGISIDHVIEIDVPDEEIVKRLSGRRQHPASGRVYHVVYNPPKVEGKDDETGEDLVQRPDDQEETIRKRLASYHTETEQLVGFYQGRAASGENAPTYDKLDGLRTIEDVQKDLFNILDK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKN1_CARAU
Sequence: MKFLLPSIVIFLVLCQVFGEELGPKEDLDYWTGSNQVQDEWLQADPFREIIRRMTRKPRPHQFIGLMGKRSPANAQITRKRHKINSFVGLMGKRSQEEPESYEWGTVQIYDKRR
What is the function of this protein?
Substance P produces a voltage-dependent inhibition of calcium current in retinal bipolar cells.  It can enhance learning and memory, may regulate social approach and feeding behaviors, and can accelerate the functional recovery in postural balance in response to light after unilateral labyrinthectomy.
What are the official names of this protein?
Protachykinin, Gamma-preprotachykinin, Gamma-PPT.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCSPB_THEM4
Sequence: MTIFELSKEGRKAYNLPKNNIKDYGFDFPNHLMRGKEPRLPQVSELDIVRHYTNLAAKNYAVDVGFYPLGSCTMKYNPKINEKLASLEGFTMIHPCQPREVTQGALQLMYELKEMLCEISGMDDMTLIPSAGAHGELTGMLIARAYHLSRGDTKRKKAIVPDSAHGTNPASAMMAGFEVVELKSGKDGRIDLEELEKHLDDEVAVLLLTNPNTLGLFEKDIIKIAETVHKHGALLYYDGANLNAILGRTRPGDMGFDIVHLNLHKTFSTPHGMGGPGSGPVGVKKHLAKFLPIPEIIKESDVYKFNYNKSESIGFIRSFYGNFSVLVRAYVYIKTMGNDGLKKVGQMAVLNANYLRKKVSKIMDIAYPDMCMHEFVATCEKLTKETGVKALDIAKRLLDYGIHAPTMYFPLIVHEDFMIEPTETESKDTLDEFTKILEKIFIEAKENPELVKNAPYTTPVRRLDEASASRKPIVKYNFEEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: CTCN2_ECHES
Sequence: MMIKIAVVLCAVMATSMVFANDVKEQELADLLDLLISEEVSSPDDAVAESWGHKLRSSWNKVKHAVKKGAGYASGACRVLGHSPQEARAKVLEAFPEMKESDLDEEQVGKYCAVAHAIHGR
What is the function of this protein?
Has antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and against fungi with minimum inhibitory concentration (MIC) between 0. 78 uM and 50 uM.  Shows little hemolytic activity at concentrations up to 12. 5 uM but >50% lysis at 100 uM.
What are the official names of this protein?
Centrocin 2, EeCentrocin 2.
Protein: PAT_SALAR
Sequence: MNRLPSSASALACCAHALNLIEKRTLSHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVNTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAILAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVTFGNINAMRMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPDLVHDARGKGMLMAIEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV
What is the function of this protein?
Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline.  This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal.  Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Putrescine aminotransferase, PAT, PATase, Cadaverine transaminase, Diamine transaminase, Putrescine transaminase, Putrescine--2-oxoglutaric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. Putrescine aminotransferase subfamily.
Protein: ATPA_RHDSA
Sequence: MVNIRPDEISSIIRQQIDKYDQGVQVANVGTVLQIGDGIARVYGLDQVMAGELLEFEDETIGIALNLESDNVGVVLMGEGRAILEGSSVKATGKIAQVPVGDGYLGRVVNSLGAPIDGKGDISSSDTRLIESAAPGIISRKSVCEPIQTGITAIDSMIPIGRGQRELIIGDRQTGKTSVAIDTIINQKTEDVVCVYVAIGQKAASVASIVTQLEEKGALDYTVIVAANADEPATLQYIAPYTGAAIAEYFMYKGKATLIIYDDLSKQASAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLSDALGGGSMTALPIIETQAGDVSAYIPTNVISITDGQIFLSGDLFNAGIRPAINVGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFSQFASDLDQATRNQLARGQRLREILKQPASSPISVEEQVAIIYTGINGFLDEVPVNKVKEFVSQLRTNLKNSKPKFAESIRETKALGSDAEELLKSAIADVKQSMG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: OMPX_CHLPN
Sequence: MKRQKRKQSITLIEMMVVITLIGIIGGALAFNMRGSIHKGKVFQSEQNCAKVYDILMMEYATGGSSLKEIIAHKETVVEEASWCKEGRKLLKDAWGEDLIVQLNDKGDDLVIFSKRVQSSNKK
What are the official names of this protein?
Putative outer membrane protein CPn_0818/CP_1053/CPj0818/CpB0847.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein.
Protein: ISCR_YERE8
Sequence: MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGDRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINVNLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: RR4_CHLVU
Sequence: MARYRGPKLRIVRRLGELPGLTQKNCTRDFPPGQHGPKKKGGGNQKTKESQYAVRLKEKQKLRFNYGISERQLMSYVREARKRKGSTGEILLQILEMRLDTIIFRLGFAPTIAAARQLINHGHIVVNGRRVDIPSSLCKVNDSISVALNSQNFVKNLLQSFTKTLDAPYLEVNQEKLSAVVRDNIPREAVSLQINELLVVEFYSRKV
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ISPT_CHLTE
Sequence: MPQWFTSKSDPEDTRIQETLKSSCVLPRHIGIIMDGNGRWAKIKGKSRIAGHVAGVESVRDVVEASSQLGIENLTLFTFSIENWKRPKPEISALMKLLIKVLRKEAVKLLENDIRLEVIGDMEMIPDDVRKTLDETIELTRKNRGMAMTIALSYSGKWDITQACRHIALQVKQGLLDPETIDENLFASYLSTASMPDPDLLIRTSGEYRISNFMLWQNAYSEIIFSNTLWPDFRRNELYEAIREFQKRERRFGKTSEQLKTNEVE
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: Y1455_PYRHO
Sequence: MNVLSGIGEFLVLFGTVFYFLSTLGLIRMPDVYNRMQTATKSVTLGSLSTIIGVGLWALGEGLSLAWLTKTIVIAVFLLLTNPISAHTLIRGAYKSGIPLWEGSVVDKYKEHLKEKEGAE
What are the official names of this protein?
UPF0091 protein PH1455.
What is the protein family that this protein belongs to?
Belongs to the UPF0091 family.
Protein: UT14B_MOUSE
Sequence: MNMARNVTDLLALSQQEELVDLPENYPLSTSEDEGDSDGEGKRQKLLEAVSSLGRKNKWKLAERSEASRMVSEFNVTSEGSGEKLVLSDLLGSATALSSVAAVKKQLHRVKSKTLTPPLNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEKEPPAVAPIEHVFTDWKVRTPLEQEVFNLLHKNKQPVTDPLLTPVETASIRAMSLEEAKIRRAELQRMRALQSYYEARARREKRIKSKKYHRALKKGKAKKALKEFEELWKDCPNAALQELEKMEKARMTERMSLKHQGSGKWAKSKAIMAKYDPEARKAMQEQLAKNRELTQKLQVVSESEEEDGCTEEGIVSVSHGMDDLQMNADGVNPWMLSSCNSNAKRGEIKTDPEQMPEFVAHVSSESEGDERPVAEELVLKERSFQERVDPNNAKLMDGQETEDSDSQEVLQKLNKESHQSDNQKVSSEENVLHIQREDLASEKLLVLQRLERAHVLEQQGELSKEEHYPKKGLSRPLLKGDWKEMKPLTNPDASGGKKKKEQMIDLRNLLTANSSPVRSLAVPTIQQLEDEVETDHKQLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGLKPSAKKRRRFLIKAPESSPRKDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTVPKVGTKLGHIIKPIKAENVGYCSSTRSDLSILQSSQKCLSRKQQKQLKKLSSAD
What is the function of this protein?
Essential for spermatogenesis.  May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 14 homolog B, Juvenile spermatogonial depletion protein.
What is the protein family that this protein belongs to?
Belongs to the UTP14 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YEEX_ESCF3
Sequence: METNKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERREISKKLKAIGELKNGEAKAE
What are the official names of this protein?
UPF0265 protein YeeX.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: MMP24_MOUSE
Sequence: MPRSRGGRAAPGQASRWSGWRAPGRLLPLLPALCCLAAAAGAGKPAGADAPFAGQNWLKSYGYLLPYESRASALHSGKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDRKEADIMIFFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGLEHSNDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRIHSPSERKHERHPRPPRPPLGDRPSTPGAKPNICDGNFNTVALFRGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCKQKEVERRKERRLPQDDVDIMVTIDDVPGSVNAVAVVVPCTLSLCLLVLLYTIFQFKNKAGPQPVTYYKRPVQEWV
What is the function of this protein?
Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence (PubMed:19805319, PubMed:24952463).  Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia (PubMed:19805319).  Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence (PubMed:24952463).  May play a role in axonal growth (PubMed:11714638).  Able to activate progelatinase A.  May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans.  Cleaves partially fibronectin, but not collagen type I, nor laminin (PubMed:10622708).
What are the official names of this protein?
Matrix metalloproteinase-24, MMP-24, Matrix metalloproteinase-21, MMP-21, Membrane-type matrix metalloproteinase 5, MT-MMP 5, MTMMP5, Membrane-type-5 matrix metalloproteinase, MT5-MMP, MT5MMP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
[Matrix metalloproteinase-24]: Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Recycled back to the plasma membrane through the trans-Golgi network via interaction with APBA3. SUBCELLULAR LOCATION: [Processed matrix metalloproteinase-24]: Secreted, extracellular space, extracellular matrix. Note=Also shed from cell surface as soluble proteinase, by a proteolytic cleavage.
Protein: PGK_LEPBP
Sequence: MKLPLLEEQNLKGKRVFVRVDFNVPVENGKATDRTRIEKTLPTLELLISKGAKIILGSHLGRPKGGPEPKYSMKPVFDVLSELVKTKVSFSESVIGSDVVKMTNALGEGEILLLENLRFHKEEEENVASFCKELAKLADVYVNDAFGTAHRAHASTEGVAHLLPAFAGLLMRKEIEVLSGLLAKPERPFVAIVGGSKVSSKFAILKNLLEKVDHLLIGGGMAYTFLKSRAVPVGKSLVEPEFESQAFQLIDRAGIQGVDLQIPVDHIIADAFDPNAKTKSVDKMGIIDGWMGMDIGPKTIDNYVKAIKDAKTILWNGPMGVFEMDKFSKGTIEIAKAISKSKAKTVVGGGDSIAAVNKAGVADKITHISTGGGASLEFLEGRTLPGVQCLLPKEEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX11_YEAST
Sequence: MIRICPIVRSKVPLLGTFLRSDSWLAPHALALRRAICKNVALRSYSVNSEQPKHTFDISKLTRNEIQQLRELKRARERKFKDRTVAFYFSSVAVLFLGLAYAAVPLYRAICARTGFGGIPITDRRKFTDDKLIPVDTEKRIRISFTSEVSQILPWKFVPQQREVYVLPGETALAFYKAKNYSDKDIIGMATYSIAPGEAAQYFNKIQCFCFEEQKLAAGEEIDMPVFFFIDPDFASDPAMRNIDDIILHYTFFRAHYGDGTAVSDSKKEPEMNADEKAASLANAAILSPEVIDTRKDNSN
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side. Note=Intrinsic component of the inner-membrane.
Protein: TSN6_PONAB
Sequence: MASPSRRLQTKPVITCFKSVLLIYTFIFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLIFLVELVAAIVGFVFRHEIKNSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNEGCFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQYEIV
What are the official names of this protein?
Tetraspanin-6, Tspan-6.
What is the protein family that this protein belongs to?
Belongs to the tetraspanin (TM4SF) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RF1_CAMJR
Sequence: MLASKLDPFLKRFEELNSLLSSSDIINDISKMTTLSKEQKNLEPIVLKAKEYLKTLDNIEENKALLNDPELGELAKEELKTLEELKPKLEEEIKILLLPKDPNDERNIFLEIRAGAGGDEASLFVGDLVKAYARYAENRGYKLEIVSSSEGSVGGFKEIIMLVKGTGAYSRLKYEGGTHRVQRVPQTESQGRVHTSAITVAVMPEVDDIEIEINPNDLKVDVMRSSGHGGQSVNTTDSAVRITHIPTGIVVVNQDGKSQHKNKESAMKVLKARLYEMQESERLAKESEARKSQVGSGDRSERIRTYNFPQNRISDHRINLTLYRLDAIMQDGLFDEIIEPLITHHQAQALQEQNL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_RENSM
Sequence: MASNEEILAGLAEIVNEETGLAPEAVELDKSFTDDLDIDSISMMTIVVNAEEKFGVRIPDEEVKNLKTVGDAVSYIASAQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCYD_YERPS
Sequence: MTLQHKLTQFPRLDLVGNATPLEKLSRLSDYLGREIYIKRDDVTPVALGGNKLRKLEFLAADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTEQANYLTNGNRLLLDLFNVDVVMCEALNDPNQQLAELATRVEAQGFRPYVVPIGGSNALGALGYVQCSLEIAAQAAGNVAFSSVVVASGSAGTHAGLAVGLQQLLPDAELIGVTVSRSADEQRPKVAQIQQALATSLGMTDPLAKITLWDSYFAPQYGMPNEEGIAAIKLLARLEGILLDPVYTGKAMAGLLDGIEQQKFCDKGPILFIHTGGAPALFAYHPQV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.