PharMolix/UniProtQA huggingface dataset:
Protein: MET_NOMLE
Sequence: MKTPAVLAPGILVLLFTLVQRSNGECKEALAKSKMNVNMKYQLPNFTAETPIQNVILHEHHIFLGATNYIYVLNEEDLQKVAEYKTGPVLEHPDCFPCQDCSSKANLSGGVWKDNINMALVVDTYYDDQLISCGSINRGTCQRHVFPHNHTADIQSEVHCIFSPQIEEPSQCPDCVVSALGAKVLSSVKDRFINFFVGNTINSSYFPDHPLHSISVRRLKETKDGFMFLTDQSYIDVLPEFRDSYPIKYVHAFESNNFIYFLTVQRETLDAQTFHTRIIRFCSINSGLHSYMEMPLECILTEKRKKRSTKKEVFNILQAAYVSKPGAQLARQIGASLNDDILFGVFAQSKPDSAEPMDRSAMCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEARRDEYRTEFTTALQRVDLFMGQFSEVLLTSVSTFIKGDLTIANLGTSEGRFMQVVVSRSGPSTPHVNFLLDSHPVSPEVIVEHPLNQNGYTLVVTGKKITKIPLSGLGCRHFQSCSQCLSAPPFVQCGWCHDKCVRSEECPSGTWTQQICLPAIYKVFPNSAPLEGGTRLTICGWDFGFRRNNKFDLKKTRVLLGNESCTLTLSESTMNTLKCTVGPAMNKHFNMSITISNGHGTTQYSTFSYVDPVITSISPKYGPMAGGTLLTLTGNYLNSGNSRHISIGGKTCTLKSVSNSILECYTPAQTISTEFAVKLKIDLANRETNIFSYREDPIVYEIHPTKSFISGGSTITGVGKNLNSVSVPRMVINVHEAGRNFTVACQHRSNSEIICCTTPSLQQLNLQLPLKTKAFFMLDGILSKYFDLIYVHNPVFKPFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHLHSEAVLCTVPNDLLKLNSELNIEWKQAISSTVLGKVIVQPDQNFTGLIAGVVSISVALLLLLGFFLWLKKRKQIKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLTDMSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDGKKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFSELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSEDNADNEVDTRPASFWETS
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CDPK2_PLAFK
Sequence: MGNHLSVNKLKRKKKKKSFLNIYGKNTNENTSKQSNDYKYDINTSCISREGTTTLERKNLILCHSGKLEDKYIIDEKLGQGTYGCVYKGIDKVTNQLYAIKEEKKDRLKNINRFFQEIEIMKKLDHPNIVKLYETYENDNYIYLIMELCSGRELFDSIIENGSFTEKNAATIMKQIFSAIFYLHSLNIVHRDLKPENFLFQSENKDSLLKIIDFGLSKNLGTGEFTTTKAGTPYYVAPQVLDGKYDKKCDIWSSGVIMYTLLCGYPPFYGDTDNEVLKKVKKGEFCFYENDWGSISSDAKNLITKLLTYNPNERCTIEEALNHPWITQMTKSHEHVELSSTLLKNLKNFKKENELKKIALTIIAKHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLKKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKKK
What is the function of this protein?
Calcium-dependent protein kinase which acts as a sensor and effector of intracellular Ca(2+) levels probably in part downstream of cGMP-activated PKG kinase (PubMed:9247932).  During male gametogenesis in the mosquito gut, required for male exflagellation, possibly by regulating male gamete exit from the host erythrocytes.  Not required for asexual blood stage proliferation (By similarity).
What are the official names of this protein?
Calcium-dependent protein kinase 2, PfCDPK2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDPK subfamily.
Protein: ALG13_CANGA
Sequence: MSAFVTCGATVPFPALVEAVLAPEFVGCLSREGYRVLCVQFGRGYDFEAQFTSVTCTRMPLESAEVSELRQLVRDERVTVMGYKVQDVVVLGFAYSNNILQIIDRYGDVVISHAGTGSILDSLRLNKKLIVVVNHTLMDNHQKQIAEKFQNLGHILATNPTAIELCDAMKRLKHEDLIPLSSETNTEFMERLKSIAYS
What is the function of this protein?
Involved in protein N-glycosylation.  Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity).
What are the official names of this protein?
UDP-N-acetylglucosamine transferase subunit ALG13, Asparagine-linked glycosylation protein 13.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: ABDH_ECOL6
Sequence: MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVNAAVRAADAAFAEWGQTTPKARAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLAPALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTAPSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGSPDDESTELGPLSSLAHLERVSKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDNEEQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH
What is the function of this protein?
Catalyzes the oxidation 4-aminobutanal (gamma-aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA).  This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4-aminobutanal.  Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Gamma-aminobutyraldehyde dehydrogenase, ABALDH, 1-pyrroline dehydrogenase, 4-aminobutanal dehydrogenase, 5-aminopentanal dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. Gamma-aminobutyraldehyde dehydrogenase subfamily.
Protein: CCA_STRPD
Sequence: MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLGRPIHDVDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVSFVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLKQKRLRAVGKAEERFEEDALRIMRGFRFAASLDFDIEATTFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIACQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTSNDFQRYVTKLIALYRIRQERSFEKLDIYQYGKKMASLVEDLRKAQSLSVDMDHINTLDQALVIHDKHDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREELAT
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
What are the official names of this protein?
CCA-adding enzyme, CCA tRNA nucleotidyltransferase, tRNA CCA-pyrophosphorylase, tRNA adenylyl-/cytidylyl- transferase, tRNA nucleotidyltransferase, tRNA-NT.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 3 subfamily.
Protein: RBS_RHOCA
Sequence: MSTVQDYPSRLSRPESRKMGTFSYLPPMGEAEIRRQVEWIVKNGWNPGIEHTEPDFAAQIYWYMWKLPMFGETDVDAILAELKACHEANPGHHVRLIGYDNFTQSQGANMIVYRGTAV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, RuBisCO small subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
Protein: PNP_DESOH
Sequence: MTEHVFEATVNGKPFTIKTGRLAKQAAGAALVQYGETIVLVTVAAATEPKEDADFLPLSVEYQEKIYSAGRIPGNYFRREIGRPSEKETLTCRLTDRPIRPLFPAGYTFETQVITTVLSMDRENDPDVLSIVGASAALTISDLPFDGPLAAVRVGRLNGTLVANPTNTELDDCDINIVVAGSRSGVVMVEGGSNVVSEAEMLEAIFFGHNALLPLIDIQDQMRNACGKPKRVIVPPEKDTELETRIAELVGDAVAQAVTEPEKDARKSALSKVRENLFQGLGEAFADRKREIKGLFSDLVKKVCRDIVLNQGRRIDGRAFDEVRPISCEVGVLPRTHGSALFTRGETQVLGVMTLGSGHDEQRVETLFGDETRPFMLHYNFPPFCVGEVKRVMGPSRRDIGHGNLAHRGISYVLPDKETFDYTIRLVSEVLESNGSSSMGTVCSCILALMDGGVPIKAPVSGIAMGLVADGDKVAVLSDILGDEDHFGDMDFKVTGTEKGITALQMDIKIKSLSREILEKALHQAKDGRIHILGKMLEALSHYRDDISPYAPKIYIVKIHPDKIREIIGPGGKVIRELQAMSNTRIEVDDSGTVKIAASTEEEARIAIKAVEDIGRVPEPGEIYEGEVVRITDFGAFIQIKNGTDGLCHISELEHHHVKSVTDVVKMGDKVRVKVLEVSPEGKIRLSRKALLPAPEKGEEDEKSAPRSRRPGGNSDRRNNR
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_TROW8
Sequence: MPATILIGAQWGDEGKGKATDLLAKDIDYVVKFNGGNNAGHTVVIGGDKYVLHLLPSGILNENVVPVIANGVVINPEVLFDEIATLNSRGVNTDKLVISANAHIIAPFHRTIDLVTERFLGKRQLGTTGRGIGPTYADKINRIGIRVQDLFDKSVLRQKIEGSLSNKNHMLVKVFNRRSVSVTEMLDYLLSFAERMRPMIADTSLLLNNALDCGKHVLFEGGQATMLDVDHGSYPFVTSSNATVGGAITGAGIGPTRVNKVIGVAKSYTTRVGAGPFPTELHDEYGEWLQKRGYEVGATTGRKRRCGWFDGVVARYATRINGITDYVLTKLDVLTGLDRIPICVGYKVGDSVFREMPVSQSDFHHAVPIYEDLPGWQCNISECESFDSLPPEARGYVLALEDLIKARISVIGTGPERENIIIRHPLGIF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y924_ARCFU
Sequence: MKNVKFIKKSESVIGLWLPILVILILFAFLVAESVIMKDIILSNSVVALATAIMASAALVTILVSNRQVQLMARQQRLKAIEDRLEKFYIPLIKAFSSYVYTAQTEDEIETIITCRRYLAGNNLLRVLPMHFKFKADKIAGSANWTFYAKEDFEQWKEALDVLWEEFLEVLKEYYTLSGTEISLPEKPDWLIGYK
What are the official names of this protein?
Uncharacterized protein AF_0924.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEA1_CICAR
Sequence: MASHDQSYKAGETMGRTEEKTNQMIGNIEDKAQAAKEKAQQAAQTAKDKTSQTAQAAKEKTQQTAQAAKEKTQQTAQAAKDETQQTAQAAKDKTQQTTEATKEKAQDTTGRAREKGSEMGQSTKETAQSGKDNSAGFLQQTGEKVKGMAQGATDAVKQTFGMANDDKDKDHFPTNRH
What are the official names of this protein?
Late embryogenesis abundant protein 1, CapLEA-1.
What is the protein family that this protein belongs to?
Belongs to the LEA type 4 family.
Protein: Y498_PASMU
Sequence: MIYINQLMENEINKENNNIKRSVISSDLLDLLDFVNVDGCLFFKFQKIDNNISTVDLNDVSRQFLDLSGYELSINRFHIDDYVSNNILCQSILFLGEFKRKWQKIYPDIKCVVIITFQNDDVGRFSTFTFHKVRDGESVFELYEINNIAQAILVEFIN
What are the official names of this protein?
Uncharacterized protein PM0498.
Protein: Y1208_ORYSJ
Sequence: MEKSHRVCKNCVANHYWLHMDNHGKSFIKVMITDFKNGVTIPAKFARNFGGQMSGTVKLETRNGKTYEVQVAKELNNLVLRSGWERFASAYELEKGDILVFIYSGNSHFKVWIYDPSACEKGLPCIITEQLPRVQQRSISHNNHTQLKRNAKSAKLYVDSSGHSKETSEINPANSPSWKPTERVPSSEELDEPVDLANVQKATKSFYSLPRMCNMTSAQKAEVDALEKRIKPQIPFYITVMDKASATDGLLAISKDYAVSYLLDKNETIKLCHSGRSMTWDISLDIDTDDQYALSTGWLDFIRNNHLQEGDICVFEASKNKRGVALIFHPLKQSHHPKPPGCVPSTKFPRHGVSKPNYIVSRFTTLSGQLKIKVEAKVQAIQSEIPIFVAVMRESFIRGRSRYMCFSAKYAAKYLPREKNKIMRLRLPNKSYKYKAVFKINNKVHKLGGGWGKFVDDNKIKLGDICLFQLMKNKKKLMMMVHIIRKSEFC
What are the official names of this protein?
B3 domain-containing protein LOC_Os12g40080.
What are the subcellular locations of this protein?
Nucleus.
Protein: CARB_THEPX
Sequence: MPKYKDINKVLVIGSGPIIIGQAAEFDYSGTQACKSLKEEGLQVVLVNNNPATIMTDTDIADIVYIENPTVCVVEKIIAKEKPDGILATLGGQTGLNLAVKLKEEGILDKYNVKLLGTSFESIKTAEDRKLFKRKMQEIGEPVAESVTVTNIEDALKFAKNYGYPLIIRPAYTLGGTGGGIAHNDEELISIVSLGLKKSMVGEVLVEKSLYGWKEIEFEVMRDADDNCITICSMENFDPVGVHTGDSIVVAPTQTLSDYEYQMLRSASIKIIKALKIEGGCNIQFALDPESHKYYVIEVNPRVSRSSALASKATGYPIAKVAAKIAIGLRLDEIKNPVTGKTTAFFEPALDYVVTKIPRWPFDKFYTTDRKIGTQMKATGEVMAIERSFEASLLKAVRSLEIKAYGLRLNNVKAMKTEEILKGISVPNDMRLFYIAEALRRDIDIDYINEVTKIDKWFLNKLLNIVNMEREIEKNELSEEILKKAKRMGFSDREIATIKGIEEEDVRALRKEYSIYPSYKMVDTCAAEFESVTQYIYSTYGEEDEVEIHEIPKVIVIGSGPIRIGQGIEFDYCSVKALWALRDAGIKSIIINNNPETVSTDFDTGDRLYFEPITLEDVLNIYEKEKPLGVMVMFGGQTAINLTEGLVKNGVKILGTSYESIDISEDREKFSKLLKELNINQPKGDYALTVEDAKDIALKLSFPLLVRPSYVIGGQSMEKVNTLQELIDYVKHATEISPGKPILIDKYIDGREVEIDAVSDGECVLIPGIMEHIERAGVHSGDSFSIYPARNLSEREINTIIEYTERISKALNVKGLINIQFAVKEGTVYVLEVNPRASRTVPIMSKATGVPMVKLAVEVALGKKLKELGYKSGLWPQTPYTVVKAPVFSMEKLTDAEVSLGPEMKSTGEIMGIDLSYEGALYKALEGAGLKIPKKGKILLSIAERDFQEVPSLVEKLQSLGYEIYATYRTGKYLSLMGIHVNVISLDNAIKLLKDGYFDAVINTPTKGKKPDNTGFKLRRTAVEYRIPLFTSMDTIKAALNAVAKVNVNGLSILSINEYEEIQKDNVKNLVL
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: SYE_BURMA
Sequence: MTRPVRTRFAPSPTGFIHLGNIRSALYPWAFARKMKGTFVLRIEDTDLERSTEASVDAILEGMAWLGLDYDEGPYYQMQRMDRYREVLAQMLEKDLVYPCYMSTEELDALRERQRAAGEKPRYDGTWRPEPGKVLPEPPAGVTPVLRFRNPLTGSVVWDDAVKGRVEISNEELDDLVIARPDGTPTYNFCVVVDDLDMGITHVIRGDDHVNNTPRQINILRALGGEVPVYAHLPTVLNEQGEKMSKRHGAMSVMGYRDAGYLPEAVLNYLARLGWSHGDAEIFSREQFVEWFDLEHLGKSPAQYDHNKLNWLNNHYIKEADDARLAELAKPFFAALGIDADTIARGPDLVGVMGLMKDRASTVKEIAENSTMFYRSPAPDAQALAQHVTDAVRPALAEFAAALKTAEWTKEAIAAALKAVLGAHKLKMPQLAMPVRLLVAGTTHTPSIDAVLLLFGRDVVVSRLAAALA
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_CLOP1
Sequence: MSRSIKKGPFVHAGLLKKIEEMNQNGDKKVIKTWSRSSTIFPQMIGHTIAVHDGRKHIPVYVTEDMVGHKLGEFVLTRTFKGHIKNEKTSKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ARGJ_AJECG
Sequence: MRNPKSFCVVAGFVRLPKSSLGQARYYSIPNDVSIPASKRKFIPSSGTYPKGFLVAGAHAGVKESNTQFPDVALICSETPCSAAAVFTTNKFQAAPVQVSKQVLEKRQGTGIRGVVINSGCANAVTGKGGLEDAKMMSAKVDECNGTPSTGPQDTSTLVMSTGVIGQRLPIKKILDAIPTAHSNLASTHSTWLATARAICTTDTFPKLLSRTFTLPSSPNRQYCLAGMTKGAGMIHPNMATLLGILCTDVPISPSALKALLTHAVSRSFNAISIDGDTSTNDTIALLANGAAGGEAIITTSSPDYAAMQTILTSFAQSLAQLVVRDGEGATKFITVRVCNSPSHADAKVIASTIARSPLVKTALYGKDANWGRILCAIGYAQGIAEGTVVPERTSVSFRPVDGSAELKLLVNGEPEAVDEERAARILQDEDLEIVVDLGGGQKGEKGLGGEEGLYWFCDFSHEYVTINGDYRT
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RF1_METM7
Sequence: MSGNSSTDMYLFKKSLRELKGKKGKGTELISVYVPAGRRLSDISQYLRQELSQSSNIKSKTTMKNVQSAIEVILQRLKLLKEPLEMGVIIFAGMIPRGGPGTEKMEVYVLEPPEPVKTFVYRCDSLFYTDPLEDFIQDTEVYGVILVDRNEATIGTVKGKTITVLKKLTSGVPGKFKAGGQSARRLERLIDDAAHQFMVRIGEYATESFMPILEEKKLKGLLLGGPGNTKNEFAEKDYLHHELKKKIIDTFDLCYTEEFGIRELLEKASDLLRDLDLMKEKNLIQRFFKELIKDDGGLSAYGEAQVMKYLGMGAIDTLIVTEDIGITRVTVKCNNCDYTQEVNVKTNEMFKFEDQLKTKACPTCGGAMYIDEEKDIIEYLSELCNVHNTDIIVVSTDTEEGSQISRAFKGMAAILRYKL
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARFC_MYCTO
Sequence: MEHVHWWLAGLAFTLGMVLTSTLMVRPVEHQVLVKKSVRGSSAKSKPPTARKPAVKSGTKREESPTAKTKVATESAAEQIPVAGEPAAEPIPVAGEPAARIPVVPYAPYGPGSARAGADGSGPQGWLVKGRSDTRLYYTPEDPTYDPTVAQVWFQDEESAARAFFTPWRKSTRRT
What is the function of this protein?
Required for wild-type expression of ArfA and ammonia secretion, not however part of an ammonia transporter.
What are the official names of this protein?
Uncharacterized membrane protein ArfC.
What is the protein family that this protein belongs to?
Belongs to the ArfC membrane protein family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GATA_CLOBM
Sequence: MDLTKLTAHELKDILSNKEVKAEEITRAFLDRINLVDNKLGAYLYVSEEEAIKKAKEIDGKIEKNEELKALSGIPVGIKDNINVKGMQNTCASKILQGYTSPYDAHVTEKIKKEEGIILGKLNMDEFAMGSSTENSAFKLAKNPWDLERVPGGSSGGSAVAVSGCEATLSLGTDTGGSVRQPASFCGIVGLKPTYGRISRSGVVAFGSTLDQVGPMGKDVEDCALLTSAIAGLDKKDFTTADKEVPDYKKSLTKDIKGKKIGIPKEFFGEGLDEKVRKSVEEAIKVLEENGAEVKPCSLPLMDYALSAYYIISSAEASSNLARFDGIRYGYRSKNFKDAKDIYLKSRSEGFGDEVKRRIMLGTYVLSAGYYDAYYKKALKVRKLIKDDFQRVFKDFDAIVSPTSPTTAFKVGEKKDDVMSMYLSDIYTVPISVAGVPAISLPCGMIDGLPVGLQIISDYFKEDVLFNLAYSYEQSVDFYKMRADF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: CYB_MIRZA
Sequence: MTNIRKMHPLMKIMNSSFIDLPAPSNISSWWNFGSLLGACLAIQIITGLFLAMHYTADTATAFSSVTHICRDVNQGWIIRYIHANGASMFFMCLFIHVGRGMYYGSFTLSETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPLGTTSDSDKIPFHPYYTIKDLLGLLFLLLLLMMLVLFSPDLLGDPDNYTPANPLITPPHIKPEWYFLFAYAILRSIPNKLGGVLALIMSILILAILPLLQTTKQRSMVFRPFSQIMFWTLTADLFTLTWIGGQPVEYPFVIIGQIASILYFSLILIIMPTVSLIENNMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSRAB_VIBCH
Sequence: MKRLFAWGAPLFALVALTLSLFSQADTKPSTIDSTSANYQQATLAGGCFWCTESDMEKLPGVVDVISGYAGGDVDNPTYKQVSSGKTGHIEVIQVTFDPKIVTYEQVLDNFFRHIDPTDDQGSFVDRGEQYRPAIFYHNAEQLEVAKRFMMEIDQLGIFKKPLKTELIEFKKFWPAEDYHQDYYKKNKVRYNYYRYASGRDQYLDEIFGADRNTHPKTLRQWIDEKNGQANVKAYVRPSDEQIRAKLTSLQYKVTQRDGTERPFDNEYWDNKEEGIYVDIVSGEPLFSSTDKYDSKTGWPSFTQPLNSSYIVTKDDNSLFYTRTEVRSRFADSHLGHVFNDGPAPTGLRYCMNSAAMRFIPKQEMAAQGYGEYLALFK
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA/MsrB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MsrB Met sulfoxide reductase family.
Protein: TNFL6_FELCA
Sequence: MQQPLNYPYPQIYWVDSRASSPWGPPGSVLPCPSSVPGRPGQRRPPPPPPPTLPPPPPPPPLPPLPLPPLKTRRDHNTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQKHVASSLEKQIGQLNPPSEKRELRKVAHLTGKPNSRSIPLEWEDTYGIALVSGVKYKKGGLVINDTGMYFVYSKVNFRGQSCNNQPLNHKVYMRNSKYPQDLVLMEGKMMNYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVSFEESKTFFGLYKL
What is the function of this protein?
Cytoplasmic form induces gene transcription inhibition.
What are the official names of this protein?
Tumor necrosis factor ligand superfamily member 6, Fas antigen ligand, Fas ligand, FasL.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle lumen. Lysosome lumen. Note=Colocalizes with the SPPL2A protease at the cell membrane. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination. SUBCELLULAR LOCATION: [Tumor necrosis factor ligand superfamily member 6, soluble form]: Secreted. Note=May be released into the extracellular fluid by cleavage from the cell surface. SUBCELLULAR LOCATION: [FasL intracellular domain]: Nucleus. Note=The FasL ICD cytoplasmic form is translocated into the nucleus.
Protein: MNME_BURTA
Sequence: MLATDSDPIVAIATASGRGGIGVVRISLGRAGEAAALALSDALCGARLTPRHASYVPFLDGAGEPLDRGIALYFPAPHSYTGEHVLELQGHGGPIVLQLVLQRCLDAGRAYGLRLAEPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAGRSLDGAFSRDIHALVDDVIALRMLVEATLDFPEEEIDFLEAADARGKLAHIRERLAHVLGDARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDKVAQTIQVEGIPLHIIDTAGLRETEDEVEKIGIARTWGEIERADVVLHLLDARSGLGPDDEAIAARFPAGVPVVRVLNKTDLTEAPASVARVGSGAERADLCEVRLSAKRGDGIDLLRGELLRIAGWQAGAESVYLARERHLIALRAAQAHVARAAEHADQNAQALDLFAEELRLAQEQLNSITGEFSSDDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_FLAJ1
Sequence: MTEGNFVDYVKIYVSSGKGGKGSTHLHREKFIEKGGPDGGDGGRGGHVYLVGNKGLWTLFHLKFARHIKAGHGGDGGSDRSTGADGEDKFIEVPLGTVVKDKETGEVLFEITEDGEKRILAKGGKGGLGNWHFRSSTNQTPRYAQPGLPGLEMDVILELKVLADVGLVGFPNAGKSTLLSVLTSAKPKIADYPFTTLKPNLGIVAYRDFQSFVIADIPGIIEGAAEGKGLGHYFLRHIERNSTLLFLVPVDTPDIKAEYDILVNELTKYNPEMLDKERLLVISKCDMLDDELKAELKAELDVSFKDIPYMLISSVAQQGLTDLKDKLWKMLNE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.