PharMolix/UniProtQA huggingface dataset:
Protein: HIS3_METFK
Sequence: MSDTWLDKVHWTPDGLVPVIAQEAGTNKVLMFAWMNRESLRLTAETGQAVYWSRSRNRLWHKGEESGHVQKVHEIRLDCDEDVILILVEQVGGIACHTGRHNCFFQKLEQDGWVTDQAIIKNPEDIYHHE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSY1_THEMA
Sequence: MLNFFLITIQFLSGAVMYSHIIAKIKGIDLRKIRDGNPGSSNLWRAAGWKYGFPALMLDYFKGTFPIAFFVWNESFHVNRYVIAFAALSGILGHAFSPFLKFKGGKAIATTFGAWSVLTKWEGPMVLGTVFTIFSILHRLRGKNKTTPEEDAFRVMIGFAALLIYTMWKVFNGMPELAILYFGNFLIVFYKHRLELRRYLKGV
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 1, Acyl-PO4 G3P acyltransferase 1, Acyl-phosphate--glycerol-3-phosphate acyltransferase 1, G3P acyltransferase 1, GPAT 1, Lysophosphatidic acid synthase 1, LPA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPS2L_MOUSE
Sequence: MAELNTHVNIKEKIYAVRSVVPNKSNNEIVLVLQQFDFNVDKAVQAFVDGSAIQVLKEWNMTGKKKNNKRKRSKSKQHQGNKDAKDKVERPEVGPLQPQAPLVQNGHMNGCEKDSSSPDSTREKLALTPREKKISILEEPPRAQRGVTEGGRLLQQKMSLDGNPRAIHGPSERSDGPQWSAGQPCNPSKPKAKTSPVKSNAPAAHLEIKPDELAKKRGPNIEKSVKDLQRCTVSLTRYRVMIKEEVDSSVKKIKAAFAELHNCIIDKEVSLMAEMDKVKEEAMDILTARQKKAEELKRLTDLASQMAEMQLAELRAEIKHFVSERKYDEELGKAARFSCDIEQLKAQILICGEITHPKNSYSSRTPCSSLLPLLNTHAVASGKQGNFARKSSGHNKPSEGKAANPKMVSGLANTADACHQTMPTNKQQNGPSSQRRRFNPQYHNRLNGPAKSQGGGNEADPMAKSNSRHEHRRQPHNGFRPKNKGGAKNQEAPLGTKAPEAPPHSEKARRRQHAADNLEARPFRGNVSRVSQCNLCPSRIEVSTEATVLSVPAVTLVA
What are the official names of this protein?
SPATS2-like protein.
What is the protein family that this protein belongs to?
Belongs to the SPATS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: AP4A_BOVIN
Sequence: MALRACGLIIFRRRLIPKVDNTAIEFLLLQASDGIHHWTPPKGHVEPGESDLETALRETQEEAGIEAGQLTIIEGFRRELSYVARAKPKIVIYWLAEVKDCDVEVRLSREHQAYRWLELEDACQLAQFEEMKAALQEGHQFLCSTAT
What is the function of this protein?
Catalyzes the asymmetric hydrolysis of diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) to yield AMP and ATP (By similarity).  Exhibits decapping activity towards FAD-capped RNAs and dpCoA-capped RNAs in vitro (By similarity).
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical], Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Ap4A hydrolase, Ap4Aase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Nudix motif 2.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: MNMG_PARL1
Sequence: MTRDFDVIVIGGGHAGCEAASAAARAGARTALITHKLATIGEMSCNPAIGGLGKGHLVREVDALDGLMGRVADQAGIQFRLLNRRKGPAVRGPRAQADRKLYRAAMQEAILNHRNLEVIEGGVSDLIVEDGHVAGVIAEDGRQFRARRVVLTTGTFLRGVIHLGTQRIPAGRVGEAPALGLSDRLYGLGFQLGRLKTGTPPRLAGDSIDWSSLEVQPGDDPPVPFSFLTTEITTPQVPCHITRTTAEGHRIIEDNLHVSPVYSGQIEGVGPRYCPSIEDKVVRFRERDSHQIFLEPEGLDDDTIYPNGISTALPEEVQLAFLKTIPGLENVVMRRAGYAIEYDYIDPRELRPTLETKRLGGLYLAGQINGTTGYEEAAAQGLIAGLNAALAERGAEPFILDRAQAYMGVMVDDLITRGVSEPYRMFTSRAEYRLTLRADNADQRLTAAGIGAGVVGERRVMAYEAKARALEAARVLCDGLRLSPTELARRGLKVNQDGVARTAMDLLAYPDIDAGVLAGVWPELAALEPHIAEQMGIEAQYAGYLDRQDADIKAFRRDEGLRLPAEIDYASVLGLSHEVRQKLAKARPATLGQAARVDGVTPAALTTLMIHVKQKRSA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_ZYMMO
Sequence: MRTGVIAKKVGMTRLFQEDGRHVPVTVLKLEDVQVVAVKNKDQDGYVAVQLGAGSAKAKNVTKPVRGHFAKAEVELKAKLVEFPVSEDAVLEVGTSISADHFIAGQLVDISGQTQGKGFAGAMKRWGFGGLRATHGVSLSHRSHGSTGNRQDPGRVFKNKKMAGHMGARQRTQQNLEVISTDAERDLIFVRGSVPGSKGAWLIIRDAVKVARPTDAPYPAAIKAANGNEAPAAPVAAEGQEG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RL14_RHOJR
Sequence: MIQQESRLRVADNTGAKEILCIRVLGGSSRRYAGIGDIIVATVKDAIPGGNIKKGEVVKAVIVRTTKERRRPDGSYIKFDENAAVLIKPDNDPRGTRIFGPVGRELREKKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RN123_RAT
Sequence: MTSKGAAMSFSRKSYRLTSDAEKSRVTGIVQEKLLSDYLYRIFSSPDHGTPAATSRKPLNFHNLPEHVDQLLQVDDEESQGQVEGRLGPSTVVLDHTGGFEGLLLVDDDLLGVIGHSNFGTIRSSTCVYKGKWVYEVLISSQGLMQIGWCTINCRFNQEEGVGDTHNSYAYDGNRVRKWNVTTTNYGKAWAAGDIVSCLIDLDDGTLSFCLNGVSLGTAFENLSRGLGMAYFPAISLSFKESVAFNFGSRPLRYPVAGFRPLQDPPFADLVRAQRLLGCFQTVLSVELDPVEGRLVEKESSEWQLHGQPTVLLTLAHIFHHFAPLLRKVYLVEAVLMSFLLGIVEKGTPEQAQSVVHQILDLLWLFMEDYEVQDCLKQLMMSLLRLYRFSPIVPDLGLQIHYLRLTMAVLRHEKSRKFLLSNVLFDMLRSVVFFYIKSPLRVEEAGLKELIPTTWWPHRSSREGRDGQEAKEETTEERQRRRAYERGCQRLKKRIEVVEELQVQILKLLLDNKDDNGGEASRYIFLTKFRKFLQENASGRGNTPVLCPPEYMVCFLHRLVSALRFYWDEYKASNPRASFSDEAYIPPQIFYNGKVDYFDLQRLGGLLSHLRKTLKDDLASKANIVIDPLELQAATMDDLDEDEEPAPTAAQSWRARQRPVQALAIGGALPLPRPGWLSSPTLGRANRFLSTAAVSLMTPRRLLSTMEKVKVRSLNVEQRTREDIEGSHWNEGLLLGRPPEEPERPLTENSLLEVLDGTVMMYSLSVHQQLGKMVGVSDDVNEYAMALRDTEDKLRRCPKRRKDILAELTKSQKVFSEKLDHLSRRLAWVHATVYSQEKMLDIYWLLRVCLQTIEHGDRTGSLFAFMPEFYLSVAINSYSALKNYFGPVHSMEELPGYEETLTRLAAILAKHFADPRIVGTDIRDSLMQALASYVCYPHSLRAVERIPEEQRIAMVRNLLAPYEQRPWAQTNWILVRLWRGCGFGYRYTRLPHLLKTKPEDANLPSLQKPCPSTLLQQHMADLLRQGSDVAPSFLNSVLNQLNWAFSEFIGMIQEIQQAAERLERNFVDSRQLKVCATCFDLSVSLLRVLEMTITLVPEIFLDWSRPTSEMLLRRLAQLLNQVLNRVTAERNLFDRVVTLRLPGLESVDHYPILVAVTGILVRLLAHGPSSETEQATSVLLADPCFQLRSIRYLLGQPEPLAPGSALPAPDRKRFSLQSYADYISAEELAQVERMLAHLTAASAQAAAASLPTNEEDLCPICYAHPISAVFQPCGHKSCKACINQHLMNNKDCFFCKATIVSVEDWDKAASTSATSSAA
What is the function of this protein?
Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase.  Promotes the ubiquitination and proteasome-mediated degradation of CDKN1B which is the cyclin-dependent kinase inhibitor at the G0-G1 transition of the cell cycle.  Functions also as an inhibitor of innate antiviral signaling mediated by RIGI and IFIH1 independently of its E3 ligase activity.  Interacts with the N-terminal CARD domains of RIGI and IFIH1 and competes with the downstream adapter MAVS.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF123, Kip1 ubiquitination-promoting complex protein 1, RING finger protein 123, RING-type E3 ubiquitin transferase RNF123.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLA_HALH5
Sequence: MIINHNLPAMNAHRNMGINLNQGQKAMEKLSSGLRINRAGDDAAGLAISEKMRAQIRGLDQASRNSQDGISLIQTAEGALDEVHSILQRMRELAVQSSNETNVEQDQAALNDEFQQLVEEIERIKDTTQFNTQKLLDDTVDTVQLQVGANSGELIELDLTKVDLSAIHTALAAEDITDHTNAQSAIDAIDEQLKAVSEGRSYLGAMQNRLEHTIKNLDNASENLQAAESRIRDVDMAKEMMEFTRTNILNQASQAMLAQANQQPQAVLQLLR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
Protein: APT_STAAC
Sequence: MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIPL2_DANRE
Sequence: MEGRHDNSPTQAFDKDVLELTVEDVYDISYVIGRDLLKVNTGGNREISDLQFKIVRVLEMFETMVNKYNLSLEELRMEMDNMRTETDRVVAEGSSGNINTVGPNKLVVDLKDPNRPRFTMQELKEVLQERNKLKAQLLVAQEELQLYKSGVLSSQQNMVEVNLETVPQSEPLRSSITEESKEKSTIQKLFSFRPK
What is the function of this protein?
Involved in cell shape and neuronal morphogenesis, positively regulating the establishment and maintenance of dendritic spines.  Plays a role in cellular protein transport (By similarity).
What are the official names of this protein?
RILP-like protein 2, Rab-interacting lysosomal-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the RILPL family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
Protein: PGK_HISS2
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKEGKVTSDARIKATIPTLKLALEKGAKVMVTSHLGRPTEGEFKPEDSLQPVVDYLKGAGFNVRLAQDYLNGVEVNEGEIVVLENVRVNKGEKKNDPELSKKYAALCDVFVMDAFGTAHRAQASTYGVAEFAPVACAGPLLAAELEALGKALKEPQRPMLAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAEGHNVGKSLYEADLIPEAQRLSKVTNIPVPVDVRVGTEFSETALSTEKSVADVSGEESIFDIGDKSAEQLADIIRNAKTILWNGPVGVFEFPNFRKGTEIVSNAIAEATANGAFSIAGGGDTLAAIDLFGIKDKISYISTGGGAFLEFVEGKVLPAVEILEKRANG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IYD_DROME
Sequence: MDVDELISSSKLLKHWPSLFITLALIWIVKRLFFKGNRVLKTYNLDEQVEEEVEHFADLGDELQPALEDKPHVPFVPGQNLNPNGAKRLYELMRGRRSIRSFNSHPKPDLSVIEDCIRAAGTAPSGAHTEPWTYCVVQEPELKRSIREIVEQEELVNYSQRMHPQWVTDLRPLQTNHVKEYLTEAPYLILIFKQTYGLSENGKRMRRHYYNEISTSIAAGILLCALQAAGLASLVTTPLNCGPALRNLLGRPVNEKLLILLPVGYPKDGCTVPDLARKNLSNIMVTF
What is the function of this protein?
Catalyzes the dehalogenation of halotyrosines such as 3-bromo-L-tyrosine, 3-chloro-L-tyrosine, 3-iodo-L-tyrosine and 3,5-diiodo-L-tyrosine (PubMed:27643701).  Activity towards 3-fluoro-L-tyrosine is weak (PubMed:27643701).  Important for male and female fertility (PubMed:29764939).  May be involved in maintaining the viability of sperm, both during development in the testes and storage in the female spermatheca (PubMed:29764939).
What are the official names of this protein?
Iodotyrosine deiodinase, Halotyrosine dehalogenase, Protein condet.
What is the protein family that this protein belongs to?
Belongs to the nitroreductase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: LHP1_ARATH
Sequence: MKGASGAVKKKPQVLNEAGEAETAVETVGESRKISGDGGFGSDDGGGGGGGGSGESILREIGDDRPTEDGDEEEEEDEDEDDGGDEEDEEGEGEGGQEERPKLDEGFYEIEAIRRKRVRKGKVQYLIKWRGWPETANTWEPLENLQSIADVIDAFEGSLKPGKPGRKRKRKYAGPHSQMKKKQRLTSTSHDATEKSDSSTSLNNSSLPDIPDPLDLSGSSLLNRDVEAKNAYVSNQVEANSGSVGMARQVRLIDNEKEYDPTLNELRGPVNNSNGAGCSQGGGIGSEGDNVRPNGLLKVYPKELDKNSRFIGAKRRKSGSVKRFKQDGSTSNNHTAPTDQNLTPDLTTLDSFGRIARMGNEYPGVMENCNLSQKTKIEELDITKILKPMSFTASVSDNVQEVLVTFLALRSDGKEALVDNRFLKAHNPHLLIEFYEQHLKYNRTP
What is the function of this protein?
Structural component of heterochromatin involved in gene repression, including several floral homeotic genes and FLT that regulates flowering time (PubMed:9611176).  Required for maintenance of vernalization-induced repression of FLC.  As part of the PRC1-like complex, recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me), leading to epigenetic repression.  PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.  Transcriptional repressor that binds DNA on GAGA-like motif and 5'-(A/G/T)AACCCTA(A/G)-3' consensus motif in the promoters of target genes.  Recognizes and binds histone H3 tails methylated at 'Lys-27' (H3K27me) but depleted in active histone marks such as H3K4me, leading to epigenetic repression.  When in complex with LHP1, recognizes and binds histone H3 tails methylated at 'Lys-4' (H3K4me) and 'Lys-27' (H3K27me), mostly corresponding to stress-responsive genes (PubMed:27495811).
What are the official names of this protein?
Chromo domain-containing protein LHP1, Protein LIKE HETEROCHROMATIN PROTEIN 1, Protein TERMINAL FLOWER 2.
Protein: WIP2_ARATH
Sequence: MDLESESSVLESVEDNNGLIGDLDKELNSPVETSPLISKGFGLRKWKRRLRRDLVKDDTSVSMENSKALKRVLSGLVDPNAKQMHLPGPEVRQDSVGSVGSVNSVVGFVMGGESYGNGLAFAAGVDSDNSEDRSSTMSHSWDKHRGKVSGGKSVISSGDSSQQRKSSVEKSNKLRGERIKIEKENSHSSMESADSRSSNFVFMQGASYSLSSREQGGRRMMDYDDENSDHDAHTSKRKDNVEEEEEETEDYSQGDCVEESQIKSNGSSDNLDPLIVAVNSFQTLQEALQKELQKFQELGKEEPITSLHDGGESSSCIHAGHEGASEASSSYRFGSEKMGEMELTSLDSEILNLVNNVEHLEIKLEEAKRILEVKETQIRELESTINVSETCNGGTEIGIEDIFQQKVEAEIEYIIFSRSVGNLKRRIKLIEEEKTLGLSKLDKAETKAENLKNQAQDLQNHCVEITEIQEVECLKKRAFKTTRCLLLQLGLLFILYYSLLPEPEIAVPT
What is the function of this protein?
Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips (PubMed:17600715).  As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes (PubMed:25759303).
What are the official names of this protein?
WPP domain-interacting protein 2.
Protein: FTN_STAHJ
Sequence: MLSKDLLEALNDQMNHEYFAAHAYMAMAAYCDDASYEGFANFYIQQAKEERFHGKKIYDYINDRGEHAEFKSIPAPKTEFKSILETFKDGLAQEQDVTRRFYNLSEIAQKDKDYATISFLNWFLDEQVEEESTFETHIDYLNRIGDDCNTLYLYEKELAARSFDEE
What is the function of this protein?
Iron-storage protein.
What are the official names of this protein?
Bacterial non-heme ferritin.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_GLOC7
Sequence: MAEAYLLEKLKSVEQTYKELTRRLADPDIATNPDELQRVAKARSSLEETVNTYETWQKTKEEITGARQILKEAGGDSEMREMAALEVEELEEQLEQLENKLKVLLLPRDPNDDKNIMLEIRAGTGGDEASIWAGDLVRMYSRYAESQNWVVKLVSESLADMGGFKEAILEIKGDQVYSKLKFEAGVHRVQRVPVTEAGGRVHTSTATVAIMPEVDEVEVQIDPKDIEVSTARSGGAGGQNVNKVETAVDLFHKPTGIRIFCTEERSQLQNRERAMQILRAKLYEMKLREQQEAVSSMRRSQVGTGSRSEKIRTYNYKDNRVTDHRLGQNFSLVGALEGDIEVIIQSCIGKDQQERLAELANSPETAPVLN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CIP1_ARATH
Sequence: MKKHKFRETLKSFFEPHFDHEKGEMLKGTKTEIDEKVNKILGMVESGDVNEDESNRQVVADLVKEFYSEYQSLYRQYDDLTGEIRKKVNGKGESSSSSSSDSDSDHSSKRKVKRNGNGKVEKDVELVTGALKQQIEAANLEIADLKGKLTTTVEEKEAVDSELELALMKLKESEEISSKLKLETEKLEDEKSIALSDNRELHQKLEVAGKTETDLNQKLEDIKKERDELQTERDNGIKRFQEAEKVAEDWKTTSDQLKDETSNLKQQLEASEQRVSELTSGMNSAEEENKSLSLKVSEISDVIQQGQTTIQELISELGEMKEKYKEKESEHSSLVELHKTHERESSSQVKELEAHIESSEKLVADFTQSLNNAEEEKKLLSQKIAELSNEIQEAQNTMQELMSESGQLKESHSVKERELFSLRDIHEIHQRDSSTRASELEAQLESSKQQVSDLSASLKAAEEENKAISSKNVETMNKLEQTQNTIQELMAELGKLKDSHREKESELSSLVEVHETHQRDSSIHVKELEEQVESSKKLVAELNQTLNNAEEEKKVLSQKIAELSNEIKEAQNTIQELVSESGQLKESHSVKDRDLFSLRDIHETHQRESSTRVSELEAQLESSEQRISDLTVDLKDAEEENKAISSKNLEIMDKLEQAQNTIKELMDELGELKDRHKEKESELSSLVKSADQQVADMKQSLDNAEEEKKMLSQRILDISNEIQEAQKTIQEHMSESEQLKESHGVKERELTGLRDIHETHQRESSTRLSELETQLKLLEQRVVDLSASLNAAEEEKKSLSSMILEITDELKQAQSKVQELVTELAESKDTLTQKENELSSFVEVHEAHKRDSSSQVKELEARVESAEEQVKELNQNLNSSEEEKKILSQQISEMSIKIKRAESTIQELSSESERLKGSHAEKDNELFSLRDIHETHQRELSTQLRGLEAQLESSEHRVLELSESLKAAEEESRTMSTKISETSDELERTQIMVQELTADSSKLKEQLAEKESKLFLLTEKDSKSQVQIKELEATVATLELELESVRARIIDLETEIASKTTVVEQLEAQNREMVARISELEKTMEERGTELSALTQKLEDNDKQSSSSIETLTAEIDGLRAELDSMSVQKEEVEKQMVCKSEEASVKIKRLDDEVNGLRQQVASLDSQRAELEIQLEKKSEEISEYLSQITNLKEEIINKVKVHESILEEINGLSEKIKGRELELETLGKQRSELDEELRTKKEENVQMHDKINVASSEIMALTELINNLKNELDSLQVQKSETEAELEREKQEKSELSNQITDVQKALVEQEAAYNTLEEEHKQINELFKETEATLNKVTVDYKEAQRLLEERGKEVTSRDSTIGVHEETMESLRNELEMKGDEIETLMEKISNIEVKLRLSNQKLRVTEQVLTEKEEAFRKEEAKHLEEQALLEKNLTMTHETYRGMIKEIADKVNITVDGFQSMSEKLTEKQGRYEKTVMEASKILWTATNWVIERNHEKEKMNKEIEKKDEEIKKLGGKVREDEKEKEMMKETLMGLGEEKREAIRQLCVWIDHHRSRCEYLEEVLSKTVVARGQRRVSQRT
What is the function of this protein?
Positive regulator of abscisic acid (ABA)-mediated signaling pathways involved in abiotic stress responses (e. g.  osmotic stress) and leading to various plant adaptation (e. g.  stomata closure).
What are the official names of this protein?
COP1-interactive protein 1.
What are the subcellular locations of this protein?
Cell membrane. Cytoplasm, cytoskeleton. Note=Associated to the cytoskeleton in hypocotyl and cotyledon cells, but not in root cells, where observed as disconnected cytoplasmic speckles (PubMed:7753789). Localized to the plasma membrane in the epidermal cells of cotyledons and roots, including root hairs (PubMed:27372427).
Protein: CHO_ECOL6
Sequence: MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSINIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQTIADEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHDDHALRLRQSLERLRVVCWPWKGAVALKEQHPEMTQYHIIQNWLWLGAVNSLKEATTLIRAPAGFDHDGYKILCKPLLSGNYEITELDPVNDQQAS
What is the function of this protein?
Incises the DNA at the 3' side of a lesion during nucleotide excision repair.  Incises the DNA farther away from the lesion than UvrC.  Not able to incise the 5' site of a lesion.  When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA.  Then UvrC makes the 5' incision.  The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity).
What are the official names of this protein?
Excinuclease cho, Endonuclease cho, UvrC homolog protein.
Protein: IMP3_SOLLC
Sequence: MAQNGSVEQFLDVAVEAAKKAGEIIREGFYKTKHVEHKGMVDLVTETDKACEDFIFNHLKQRFPSHKFIGEETTAACGNFELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIEKKPTVGVVYNPIIDELFTGIDGKGAFLNGKPIKVSSQSELVKALLATEAGTNRDKLVVDATTGRINSLLFKVRSLRMCGSCALNLCGVACGRLDLFYELEFGGPWDVAGGAVIVKEAGGFVFDPSGSEFDLTARRVAATNAHLKDAFIKALNE
What is the function of this protein?
Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides.
What are the official names of this protein?
Inositol monophosphatase 3, IMP 3, IMPase 3, LeIMP3, Inositol-1(or 4)-monophosphatase 3.
What is the protein family that this protein belongs to?
Belongs to the inositol monophosphatase superfamily.
Protein: MIAA_ACIBC
Sequence: MSNQLPVINLMGPTASGKTALACELYERGNFELISVDSALVYKDMDIGTAKPTREEQELYPHHLIDIITPLEVYSAAQFVEDACALIDEMHSRGKTPILVGGTMLYFKALLEGLSSNLPSADANVRAAIEEKAANEGWQAVYDELVAVDPAAGVKFKVSDKQRIIRALEVYRITGQPITKLQAEQPKNVPYRYTFHNYALLPDRLELHQRIEQRLSKMWDIGFLSEVESLIEKYDLDENLPSMRSVGYRQALEFLLKSDMSLKKKQEMEDKALFATRQLAKRQYTWLRSLQEIHDFKTYLTIKQAKEDLRNSYG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: RS16_LACLM
Sequence: MSVKIRLTRMGSKKKPFYRINVADSRAPRDGKFIETVGTYNPLVTENQVTLKEERVLEWLSNGAQPSDTVRNLLSKAGVMKKFHESKLSK
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: SEP2_OSTSE
Sequence: IIGDTINGAITTADNIAGKIGII
What is the function of this protein?
May act as an antimicrobial peptide.
What are the official names of this protein?
Septenin 2.
What is the protein family that this protein belongs to?
Belongs to the Frog skin active peptide (FSAP) family. Septenin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RF1_CAMJD
Sequence: MLASKLDPFLKRFEELNSLLSSSDILNDISKMTTLSKEQKNLEPIVLKTKEYLKTLDNIEENKALLNDPELGELAKEELKTLEELKPKLEEEIKILLLPKDLNDERNIFLEIRAGTGGDEASLFVGDLVKAYARYAENRGYKLEIVSSSEGSVGGFKEIIMLVKGTGAYSRLKYEGGTHRVQRVPQTESQGRVHTSAITVAVMPEVDDIEIEINPNDLKVDVMRSSGHGGQSVNTTDSAVRITHIPTGIVVVNQDGKSQHKNKESAMKVLKARLYEMQENERLAKESEARKSQVGSGDRSERIRTYNFPQNRISDHRINLTLYRLDAIMQDGLFDEIIEPLITHHQAQALQEQNL
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TELO2_DANRE
Sequence: MGTFGTESPLRLQVSSCLKTLSTSRDSGEIVHALRTLMRCLDDGEFTRIHHTHALQVLVSAQSSHWFSRSHDEDEEEMKKLWGEIIIRGPAEQTLLTLLDTISSTGESEALDRCVSALEMFLSAARLQVLLWSRCEVSGASADSPQLTETVIGHLAALPSITSNHLHTNTPDIFLPQQYYPLLAASILDTLEKTCHALRAGRDCSLGFVSQVLGKVCIQGYSSQMFETLGPRLSFVTREDALYQRVTQKLMENVPERCTESVITGLIRSLSGAAAVSRLMGNLVLTNKKAQFVLTHKLILQQYQHPTRLLKSVLGYLAVDSSRRPLLKQVLRSVCQVWCNSSAVKHTCVEQQLYVSKALLLCVALLDDSEIQELRQEMLQCMLGGVQCRLDSNVERIRRMGMVVGECLSHRLDTPGSQLKFQYGADEEIGELKSLMESLAVNDDEEEQPDASNSLQPEPKVEAPVSSQSVASDPGNGSESELDSDDDLTPYDMSADQEKKKSAPPRYVRDCLEGLMSSDDAERFELSLQVAETLLRKNVKATQEVSVQFSKVLLHLEDRYNTALFLSLRQNAMVALTVTDIKPVVDYWTTEFYALNYSLRQRLDILEVLALAAQELSEPVTNKHTGAEPITAVTPLGQSDDITHWRQIVDKRIQSKTRRISKGVTQPVKAVPNRYAPVAGFFFFPLFRSYDRPQTTFDLLGGDHLVLGRLLHTLGLLMHLAVNAPVVSQMGRALLDFVWAVRFHTDQMVRRGVMFAVCAVFLSMPSENLLTELGDDLMETRAWLADVAESDCDSDCRSLAVQSLMLMDKNLKSQLQIPDMET
What is the function of this protein?
Regulator of the DNA damage response (DDR).  Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins.  Promotes assembly, stabilizes and maintains the activity of TORC complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.  May be involved in telomere length regulation (By similarity).
What are the official names of this protein?
Telomere length regulation protein TEL2 homolog.
What is the protein family that this protein belongs to?
Belongs to the TEL2 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Nucleus.