PharMolix/UniProtQA huggingface dataset:
Protein: TM169_BOVIN
Sequence: MEEPALVEGQSQLPSPHHNSLRKAMAAALVLDGESTMGRRKKKKKESRPESIIIYRSESETLDEEPGESEGGDQPKEEEGDDFIDYPMDDGVWNVPVDSRYVTLTGTITRGKKKGQMVDIHVTLTEKELQELTKPKASSRETTPGGRKACQLGADRGPHVVLWTLVCLPVVFLLSFVVSFYYGTITWYNIFLVYNEERTFWHKISCCPCLILCYPVLIMAMASSLGLYAAVVQLSWSWEAWWQAARDMEKGFCGWLCSKLGLEDCSPYSIVELLESDNISGNLSNKDATQEIETSAV
What are the official names of this protein?
Transmembrane protein 169.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GUAA_NITEU
Sequence: MHSAILILDFGSQYTRLIARRIRETNVYCELHPFDVSPQFIREFAPIGIILSGGPASTFTEDAPRVPQIVFELGVPVLGICYGMQAMAAQLGGEVEDAQTREFGYAELLTAPCKLFHGIQDRINSDGKPALDVWMSHGDRVNKLPPGFTAIASNAATPFAAMADETRNFYGVQFHPEVTHTRQGKAILDHFVHDICSAGYDWNMPDYVEEAIGRIRARVGNDKVVLGLSGGVDSSVAAALIHRAIGDQLVCVFVDNGLLRLNEAKQIMETFSRNLAVNVIYIDAGRQFLEQLKGITDPEQKRRTIGREFVEIFQQEAEKIENAKWLAQGTIYPDVIESAGSHTKKAGVIKSHHNVGGLPETLHLKLLEPLRELFKDEVRELGLALGLPHDLVFRHPFPGPGLGVRILGEVKYEYTELLRQADAIFIEELRNAGWYEKTSQAFAVFLPIKSVGVMGDNRSYEYVVALRAVQTEDFMTAHWAELPYTLLSRISNRIINEIRGINRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ATPB_FRAT1
Sequence: MSTGKIIQVIGAVIDVEFARDNTPKVYDALNVVEAGLVLEVQQQIGDGVVRTIAMGSSDGLRRGMEVKNTNAPISVPVGHGTLGRIMNVLGEPIDEAGPIEYTEKRSIHQAPPAYDELALSTEILETGIKVVDLICPFAKGGKVGLFGGAGVGKTVTMMELINNIAKEHSGYSVFAGVGERTREGNDFYYEMKDSNVLDKVSLVYGQMNEPPGNRLRVALSGLTIAEGFRDEKRDVLMFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAAEMGALQERITSTKTGSITSVQAVYVPADDLTDPSPATTFSHLDATIVLSRQIAELGIYPAVDPLDSTSRQLDPLVVGQDHYETARAVQKVLQRYKELKDIIAILGMDELSDEDKKIVDRARKIQRFLSQPFHVAEVFTGNPGKFVSLKDTVASFKAIVNGEYDHLPEQAFYMVGSIQEAIEKAKTL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALG6_DICDI
Sequence: MKSLNNKVGFSSLNISIVLLILMISLLARYLVSLNGYSGQSKPPMFGDYEAQRHWMEITTNLDIHQWYFNSTDNDLMYWGLDYPPLTAYLSWVFGKIGEFIEPKSMELFTSRGYETDSGKLFMRMTVIVSDLFIWLPSVWFFVKTFYKQRNISQQISAFLFISLQPGLLLIDHGHFQYNGVSLGLGLFAITFIIRDQQLLASFFFVLSLNYKQMCLYYSPAFFFYLLLSNFEFTLKFSKIFSSIFKILKIGIVVIFTFILCWIPFLSIEQASQVLFRLFPFARGLYEDKVANFWCFISIIINVKNLFTTDQLIKICLILTLVTMLPLVYGIKRIPKNKFVFIHSLINSSFSFFLFSFQVHEKTILLVSLPISLLILHHPNMVWWFILISTFSMFPLLFKDGLVIPYFAIMILYIVIGYQFKNSITRSNNQFKHQNSQENLLASSDKSFYSIYLNYWFYLNIIGMVVCHLLYQFAPHPPHLPSLWLLLVCNFSFIHFILTFFYFIKEMTTFSPIKIKSN
What is the function of this protein?
Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation.  Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity).
What are the official names of this protein?
Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase, Asparagine-linked glycosylation protein 6 homolog, Dol-P-Glc:Man(9)GlcNAc(2)-PP-Dol alpha-1,3-glucosyltransferase, Dolichyl-P-Glc:Man9GlcNAc2-PP-dolichyl glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the ALG6/ALG8 glucosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: WAG31_MYCS2
Sequence: MPLTPADVHNVAFSKPPIGKRGYNEDEVDAFLDLVENELTRLIEENADLRQRVAELDQELAAARSGAGASSQATSSIPLYEPEPEPAPAPPQPVYEAPAQPAAPQSEDTAVRAARVLSLAQDTADRLTSTAKAEADKLLSDARAQAEAMVSDARQTAETTVSEARQRADAMLADAQTRSEAQLRQAQEKADALQADAERKHSEIMGTINQQRTVLEGRLEQLRTFEREYRTRLKTYLESQLEELGQRGSAAPVDSSANSDASGFGQFNRGNN
What is the function of this protein?
Important for maintaining cell shape and cell wall integrity by localizing peptidoglycan synthesis to the cell poles.  Protects PbpB (PBP3, FtsI) from oxidative stress-induced cleavage.
What are the official names of this protein?
Cell wall synthesis protein Wag31, Antigen 84.
What is the protein family that this protein belongs to?
Belongs to the DivIVA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the cell poles.
Protein: MRAY_STRP6
Sequence: MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLFWVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQGQFDVLLLIGTMIGALLGFFLFNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKYTKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PP332_ARATH
Sequence: MLSLRYSLPYLLLQTRESSTKLFTKKPNNVVVCAARGPRPRSPRVWKTRKRIGTISKAAKMIACIKGLSNVKEEVYGALDSFIAWELEFPLVIVKKALVILEDEKEWKKIIQVTKWMLSKGQGRTMGTYFSLLNALAEDNRLDEAEELWNKLFMEHLEGTPRKFFNKMISIYYKRDMHQKLFEVFADMEELGVKPNVAIVSMVGKVFVKLEMKDKYEKLMKKYPPPQWEFRYIKGRRVKVKAKQLNELSEGEGGLSSDEDKIDNEIESEEEDGEDLSEEEEDEKELLGGSQGQITSREPSLDHLDSS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g21190, Protein EMBRYO DEFECTIVE 1417.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: RL13_CORGB
Sequence: MSTYHPKSGDITRKWYVIDATDVVLGRLATHAADLLRGKGKPLYAPNVDCGDHVIVINADKVAVTSNKREREMRYRHSGYPGGLKSMTLGRSLDLHPERTIEDSIVGMMPHNKLTAASAKKLHVFSGSEHPYAAQKPEAYEIKKVAQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: G6PI_AERS4
Sequence: MKNINPTQTQAWQALEAHFAANKETRLKDLFAQDPKRFDKFSLTFGGDILVDYSKNLITEETLKLLVDLAKETDLRSAIDAMFNGEKINMTEGRSVLHVALRNRSDRPIECDGKDVMPEVNAVLAKMKGFCEKIISGEWKGYTGKAIQHVVNIGIGGSDLGPVMITEALRPYKNHLQMHFVSNVDGTHIAETLKEIDAETTLFLVASKTFTTQETMTNALTARDWFIKIAGDKAHVAKHFAALSTNGKAVAEFGIDTDNMFEFWDWVGGRYSSWSAIGMPIALSVGFDNFEALLQGAFEMDMHFATASYEQNVPVLLALIGLWYNNFHGAESEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGNPVDHQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFLAPAISHNPIGDHHPKLLANFFAQTEALAFGKSKEQVEAEFLAAGKTLEQVEDLVPFKVFEGNRPTNSILFKSLTPKTLGALIAMYEHKIFVQGAIWNIFSFDQWGVELGKQLANKILPELNTAEAVTSHDCSTNGLINTWKAWKA
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNAA_ECO55
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: RNH2_STRTD
Sequence: MATIKEVKEQLAILRDLDDPRWASFEEDSRTGVQAAIRKRRKAILAELAEEERLETLLNYEKSLYARGIELIAGVDEVGRGPLAGPVVAAAVILPKLCKIKGLNDSKKIPKSKHEAIYNQVMKEAVAVGIGIKDNYVIDDVNIYEATKLAMIEAIEKLNPQPEHLLIDAMNLDLPIEQTSIIKGDANSLSIAAASIVAKVTRDKMMADYEQEFPGYAFAKNAGYGTKEHLSGIDKFGVTPIHRRSFEPIKSIIKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_STRPD
Sequence: MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGATPTQEFKSVKSTLQALEEIESGNVVIHPDPSAKREAVRAKIEAERLAKEEEERKIKEQIAKEKEEEGEKI
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: UPPP_PSEF5
Sequence: MDLWTAAQALILGIVEGLTEFLPISSTGHQIIVADLLDFGGERAMAFNIIIQLGAILAVVWEFRRKILDVVIGLPTQPKAQRFTINLLIAFLPAVVLGVIFADLIHAYLFNPITVATALVVGGLIMLWAERRQHQVHAETVDDITWKDALKVGCAQCLAMIPGTSRSGSTIIGGLLFGLSRKTATEFSFFLAMPTMVGAAVYSGYKYRHLFQPDDFPVFAIGFVTAFVFAMIAVKGLLKFIASHSYAAFAWYRIAFGLLILATWQFGWVDWTAAKP
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_HYPNA
Sequence: MFAVIKTGGKQYKVAEGDTIVIERLAAAAGETVTFDSVLMVGAGAGVTVGAPMVAGATVTGEVAAEVRGPKLITRKKRQRQTYRRTIGHRQDLMEVTITSINTDGKAPAKKAAAKKEEAPKADTAPKAAAAPTEEAAAGGDNLKKITGIGPALEKKLNAAGITTFAQIAALSADDIAKLEEELSLAGRFAKDGWVEQAAELAKEA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NU2C2_ANGEV
Sequence: MKDFNLFLLYGNSILPECILILSLIVTIIIDLISDEKNTPWLYLVSLTALVTSVVILLFQWKEEPVSTFFETFQINSFNNIFRLFILICSLLCIPLSIDYIQCTKTALTEFLLFILTATLGGMFLCCANDLVTIFVALECLGLSSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVYGFSLLYGLSGGEIQLQRIVNGLLTTQMYNSTGMFISMIFLLVGVGFKLSLVPFHQWTPDVYEGSPTPVVAFFSVTSKVAALALATRLFNILFPSSSTEWHLLLEILAISSMILGNFIAVTQISMKRMLAYSSISQIGYIIIGVIAAESNNGYASMITYMLIYIFMNLGTFACITLFGLRTGTDNIRDYAGLSTKDPLLTLSLVLCLLSLGGIPPLSGFFGKLYLFWCGWKAGLYFLVPIALSTSVISMYYYLKIIKLLFTKQNRQLTIYIQNYKVSSYALIPKSSIEITMIICVVASTLPGILINPIIAIAQNTFF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL1_RICFE
Sequence: MSNKKDVAVKISGGKKIREAREKVKSDALYNLTNAVERLKSASYVKFDPTLEIVMKFGIDPRHSDQMVRGVVNLPAGTGKTVRVAVICKEEREEEAKSAGADLVGSTNIIDEIKAGKINFDVCIATPDMMAVIGSVARILGPKGLMPNPKLGTVTLDIKNAIKNAKSGQVEYRAEKAGIIHAGLGKLSFSDQDLLKNLNAFIEAVIKAKPAGLKGSYLKAMYLSSTMGASVQIDLTSIA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PA1_VESMC
Sequence: GPKCPFNSDTVSIIIETRENRNRDLYTLQTLQNHPEFKKKTITRPVVFITHGFTSSASEKNFINLAKALVDKDNYMVISIDWQTAACTNEYPGLKYAYYPTAASNTRLVGQYIATITQKLVKDYKISMANIRLIGHSLGAHVSGFAGKRVQELKLGKYSEIIGLDPARPSFDSNHCSERLCETDAEYVQIIHTSNYLGTEKILGTVDFYMNNGKNNPGCGRFFSEVCSHTRAVIYMAECIKHECCLIGIPRSKSSQPISRCTKQECVCVGLNAKKYPSRGSFYVPVESTAPFCNNKGKII
What is the function of this protein?
Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity).  May act as an allergen and induce hemolytic activity (By similarity).
What are the official names of this protein?
Phospholipase A1, PLA1, Allergen Ves m I.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RADA_SULIY
Sequence: MSNEVEQKKSIKTINDLPGISQTVINKLIEAGYSSLETLAVASPQDLSVAAGIPLSTAQKIIKEARDALDIRFKTALEVKKERMNVKKISTGSQALDGLLAGGIETRTMTEFFGEFGSGKTQLCHQLSVNVQLPPEKGGLSGKAVYIDTEGTFRWERIENMAKALGLDIDNVMNNIYYIRAINTDHQIAIVDDLQELVSKDPSIKLIVVDSVTSHFRAEYPGRENLAVRQQKLNKHLHQLTRLAEVYDIAVIITNQVMARPDMFYGDPTVAVGGHTLYHVPGIRIQLKKSRGNRRIARVVDAPHLPEGEVVFALTEEGIRDAEE
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: Y088_METJA
Sequence: MPNIWGGMLEKTVKITFIFESEKRLNWEGYVNYLIFAHYFKLIYILLRNNKELLERILKDSLDNKEDYHKLGKYLHHDIMGYIRRHGYLSFLPFTPLPFYKELCEKFMTKIPEKPIIDYKCIERIENNKIIFEFEGEEECLRCLMYLKDSSIDESIKVIKSEEMVVKILEILLYILHNLL
What are the official names of this protein?
Uncharacterized protein MJ0088.
Protein: PROF1_ENTH1
Sequence: MSWQSYVDSFLVGAGKGMGGAIIGLQGGVWAASANCTPSAQESVAIGTACASNIAGLQQTGVVIGGKKYMITRVDADEGTAMGKKGAEGISIYKTKQAVIIGYFSDASVSAGQNSDATYKCAKYLMDAGY
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-1.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
Protein: PSBE_PROM1
Sequence: MAAGSTGERPFFEIITSVRYWIIHAVALPAIFVAGFLFVSSGLAYDAFGTPRPDTYFQAGESKAPVVVQRFDSKAELDTRLK
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: CSP_PLAYO
Sequence: MKKCTILVVASLLLVDSLLPGYGQNKSVQAQRNLNELCYNEENDNKLYHVLNSKNGKIYNRNIVNRLLGDALNGKPEEKKDDPPKDGNKDDLPKEEKKDDLPKEEKKDDPPKDPKKDDPPKEAQNKLNQPVVADENVDQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQGPGAPQEPPQQPPQQPPQQPPQQPPQQPPQQPPQQPRPQPDGNNNNNNNNGNNNEDSYVPSAEQILEFVKQISSQLTEEWSQCSVTCGSGVRVRKRKNVNKQPENLTLEDIDTEICKMDKCSSIFNIVSNSLGFVILLVLVFFN
What is the function of this protein?
In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
What are the official names of this protein?
Circumsporozoite protein, CS.
What is the protein family that this protein belongs to?
Belongs to the plasmodium circumsporozoite protein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Cytoplasm. Note=Localizes to the cytoplasm and the cell membrane in oocysts at day 6 post infection and then gradually distributes over the entire cell surface of the sporoblast and the budding sporozoites.
Protein: ZN365_HUMAN
Sequence: MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII
What is the function of this protein?
Involved in the regulation of neurogenesis.  Negatively regulates neurite outgrowth (PubMed:17389905).  Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis.  Involved in the positive regulation of oligodendrocyte differentiation during postnatal growth.  Involved in dendritic arborization, morphogenesis of spine density dendrite, and establishment of postsynaptic dendrite density in cortical pyramidal neurons (By similarity).  Involved in homologous recombination (HR) repair pathway.  Required for proper resolution of DNA double-strand breaks (DSBs) by HR.  Is required for recovery of stalled replication forks, and directly contributes to genomic stability.  Interacts with PARP1 and mediates MRE11-dependent DNA end resection during replication fork recovery (PubMed:23966166).  Contributes to genomic stability by preventing telomere dysfunction (PubMed:23776040).
What are the official names of this protein?
Protein ZNF365, DISC1-binding zinc-finger protein, Protein su48.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=localizes to the centrosome at all stages of the cell cycle.
Protein: AAS_SALTI
Sequence: MLFGFFRNLFRVLYRVRVTGDVRALQGNRVLIAPNHVSFIDGMLLALFLPVRPVFAVYTSISQQWYMRWLTPLIDFVPLDPTKPMSIKHLVRLVEQGRPVVIFPEGRISVTGSLMKIYDGAGFVAAKSGATVIPLRIDGAELTPFSRLKGLVKRRLFPRIQLHILPPTQIPMPEAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLAAQYRYGAGKNCIEDINFTPDTYRKLLTKTLFVGRILEKYSVEGEKIGLMLPNAAISAAVIFGAVSRRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLEDLKADVTPADKLWIFAHLLAPRLAQVKQQPEDAAIILFTSGSEGHPKGVVHSHKSILANVEQIKTIADFTANDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRNCTVLFGTSTFLGNYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLAVPGIENGGRLQLKGPNIMNGYLRVEKPGVLEVPSAENARGETERGWYDTGDIVRFDENGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSAEKMHATAIKSDASKGEALVLFTTDSELTREKLQHYAREHGIPELAVPRDIRYLKQLPLLGSGKPDFVTLKSWVDAPEQHHE
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATB1_HORVU
Sequence: MGLVKEGADMEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGTTRRGQVLEVDGEKAVVQVFEGTSGIDNKYTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKGKHAEGGGEDDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRTGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRRDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVAQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTLDAFYSRDAAH
What is the function of this protein?
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase subunit B 1, V-ATPase subunit B 1, Vacuolar proton pump subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: PDXJ_CHLPB
Sequence: MQLAVNIDHIATLRNARNEQQPDPVTAAAIAELSGASGIVCHLREDRRHIKDRDLERLRESVTTKLDLEMAMTEEMQRIAIRTKPELITLVPEKREELTTEGGFDIISHYDRLAEFIKPVRDAGIEVSLFIEPEEKAVALAAKAGADIVEMHTGPYSLKKRPEDIDAEIKRIRIAASYARDSGLRVVAGHGLNYYNILPFRRIEEIEEVSIGHALIARAALAGMETAVRDMLHLINEA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_PSEPW
Sequence: MPTTFQEIPRERPVTPLLDRADTPAGLRRLAEADLEHLADELRQELLYTVGQTGGHFGAGLGVIELTIALHYVFDTPDDRLVWDVGHQAYPHKILTGRRNRMLSLRQKDGIAAFPRRSESEYDTFGVGHSSTSISAALGMAIAARLQNSARKSIAVIGDGALTAGMAFEALNHAQEVNADMLVILNDNDMSISRNVGGLSNYLAKILSSRTYASMREGSKKVLSRLPGAWEIARRTEEYAKGMLVPGTLFEELGWNYIGPIDGHDLPTMIATLRNMRDLKGPQFLHVVTKKGKGFAPAEIDPIGYHAITKLEPADKPAAPKKASGPKYSAVFGQWLCDMAAADNRLVGITPAMKEGSDLVAFSERYPERYFDVAIAEQHAVTLAAGMACEGSKPVVAIYSTFLQRAYDQLIHDVAVQNLDVLFAIDRAGLVGEDGPTHAGSYDLSYLRCIPGMLVMTPSDENELRKMLSTGHLYNGPAAVRYPRGTGPNAPISGDLEPLEIGKGVIRRQGEKVALLVFGVQLAEALQVAEQINATVVDMRFVKPLDEALVLELAGSHALLVTLEENAIMGGAGAAVGEFLASQAVIKPLLHLGLPDIYVEHAKPAQMLAECGLDAAGIEASVKARMAKLGL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: CBP4_YEAS8
Sequence: MERPLWVRWLKVYAIGGAIIGSGFLLFKYTTPTDQQLISQLSPELRLQYEREKKLRQSEQQALMKIVKETSQSDDPIWKTGPLQSPWERNGDNVQSRDHFAKVRAEEVQKEELARIRNELSQLRSETEEKTKEIVQDKQVKSWWRFW
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor CBP4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.