PharMolix/UniProtQA huggingface dataset:
Protein: STS1_LODEL
Sequence: MMSASFHWKHRSNEQGKNPLDKSAMPSSTLHYMSTNNSTNNGTGTSTNTSGSSSHYTIAPRSFSEMVPSQQQQQQNKKRKRYSDDDSETHNETHSENNNDTSQEQFKPHNHRDQTASGLLHLQQQQLQQQHSLLLLQQLHYFHGSSKTKRTKIPKIIGQPLPTSRLIESLDKTHLEKLLHSLIDIHPELNKTIQKITPKPSLENLLLILQDKHAQLIDHLPYKCSETSDYSYLRIKPYLQEFLSCLEDYVLYYLPSNNYSETKHKLIQSLKFIDEATSTIHKLPNFTNSEYQYMRNLTYEQLINCWLILVNQETNCDTGNGLDYTEFHKIVEELDLLESLKQHGVQSGQEGFSKVIEAVQNKLGQNQILLSRQFGIDYGNDMTVSSSNGNRSGTGAGFGGGGGGASRSGSGSGTSSNALSDMITVDYSLYSLSNRSV
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: APT_PROA2
Sequence: MPIKSRIRTIPDYPKKGIMFRDITTLLKDPVGFRLVIDQITQHYLENGINFDMIIGMEARGFIIGGALSYTLGKGFVPIRKPGKLPGETVNQEYQLEYGTDKVEMHIDALEKGTRVLLVDDLLATGGTALAGAALIEKVGGVVADMAFIVNLPDIGGQKKLEEKGYSLFSLTEFEGD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_PSYWF
Sequence: MSRVAKAPVALPNGVSVTLNGQQVEVKGSKGTMSLHLHDLVELKQEDSQLILSPVSDSKEAWMHTGTMRSTLNNFVIGVSEGFERKLQLIGVGYRAQVAGNKITLNVGYSHPVEYILPEGVTAETPSQTEIILKSNDKQALGQAAAKIRGYRPPEPYKGKGIRYSDEHVVRKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RSIW_OCEIH
Sequence: MSCSKDYLNLMHIYLDGDITREDESKLSRHLEDCESCQKHFHELNRTITLMRSAERVEAPDGFTENVMANLPSEKKTVKYRRWFKLHPMWTAAAIFLVLMAGGMISTWTHSSDQLVVSAQNELIVDGDTVIVPAGVTVPGDVLVKNGDLLLLGTVDGDVTIFNGKILDNDSEMNGEGLMASVGGVNGELETIDRMFEWIWYNIKNFFKGVFSF
What is the function of this protein?
Is the anti-sigma factor for SigW.  The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation (By similarity).
What are the official names of this protein?
Anti-sigma-W factor RsiW.
What is the protein family that this protein belongs to?
Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Note=Site-2 clipped RsiW is released from the membrane to the cytoplasm.
Protein: RIP1_LUFAE
Sequence: PRGSPRTEYEACRVRCQVAEHGVERQRRCQQVCEKRLREREGRREVD
What is the function of this protein?
Inhibits protein synthesis in animal cells.
What are the official names of this protein?
Ribosome-inactivating protein luffin P1, Arginine/glutamate-rich polypeptide, AGRP.
Protein: IBD3_HIRME
Sequence: DTECVCTKELHRVCGSDGVTYDNECLATCHGASVAHDHACEGHEEHHVDEHGEDHD
What is the function of this protein?
Proteinase inhibitor.  Blocks the activity of trypsin, plasmin and sperm acrosin.
What are the official names of this protein?
Bdellin B-3.
Protein: PGK_COREF
Sequence: MAVKTLKDLLDEGVDGRHVIVRSDFNVPLNDDREITDKGRIIASLPTLKALTEAGAKVIVMSHLGRPKGEVNEKYSLAPVAEALSDELGQYVALAADVVGEDAHERANGLTEGDILLLENVRFDPRETSKDEAERGAFADELAALAADNGAFVSDGFGVVHRAQTSVYDIAKRLPHYAGRLVENEISVLEKIAENPEAPYTVVLGGSKVSDKLGVIEALASKADSIIIGGGMCYTFLKAQGHDVQKSMLQDEMIDTCKDLLERFGDKIVLPVDLTWASEFAKDAEKKVTDLDSAPEGWLSLDIGPKSVEKFADVLGASKTIFWNGPMGVFEFEAFSDGTRGVAQAIIDATANNGAFSVVGGGDSAASVRVLGLDEEGFSHISTGGGASLEFLEGKELPGVAILKD
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_JANMA
Sequence: MELKLLNDQGQAASNVAAPDTIFGRDYNEALIHQVVVAYQANARSGNRKQKDREEVHHTTKKPWRQKGTGRARAGMSSSPLWRGGGRIFPNSPDENFSHKVNKKMYRAGVCSILSQLAREGRLSVIENLSVEAPKTKLLSQKLKGMGLDSVLVITDSLDENLLLASRNLPNVLICEPRHADPVSLVFYKKILITKLALAKIEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: GLCDH_THEAC
Sequence: MTEQKAIVTDAPKGGVKYTTIDMPEPEHYDAKLSPVYIGICGTDRGEVAGALSFTYNPEGENFLVLGHEALLRVDDARDNGYIKKGDLVVPLVRRPGKCINCRIGRQDNCSIGDPDKHEAGITGLHGFMRDVIYDDIEYLVKVEDPELGRIAVLTEPLKNVMKAFEVFDVVSKRSIFFGDDSTLIGKRMVIIGSGSEAFLYSFAGVDRGFDVTMVNRHDETENKLKIMDEFGVKFANYLKDMPEKIDLLVDTSGDPTTTFKFLRKVNNNGVVILFGTNGKAPGYPVDGEDIDYIVERNITIAGSVDAAKIHYVQALQSLSNWNRRHPDAMKSIITYEAKPSETNIFFQKPHGEIKTVIKWQ
What is the function of this protein?
Catalyzes the NAD(P)(+)-dependent oxidation of D-glucose to D-gluconate via gluconolactone.  Is also significantly active with galactose as substrate, but not with mannose or glucose 6-phosphate.  Can utilize both NAD(+) and NADP(+) as electron acceptor, with a marked preference for NADP(+).  Physiologically, may be involved in the degradation of both glucose and galactose through a non-phosphorylative variant of the Entner-Doudoroff pathway.
What are the official names of this protein?
Glucose 1-dehydrogenase, GDH, GlcDH, Galactose 1-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Glucose 1-dehydrogenase subfamily.
Protein: KHSE_WOLSU
Sequence: MTISVPATSANLGPGFDTLGLALELKNRFSIKPSSLSSIQIRGEGSKNPKLRVDNIFVRIFQETFAKLTEERTNFRFQFHNQIPISRGLGSSSAVIIGAISAAFMMAQKKATPEEILSLALAYESHPDNITPACVGGFTVATTRENSVFYIQKPLPDSIKAVVVIPHRPTSTSYSRQTLPKRYSMRDSVFNLSRSSLLTAAFFSERWDLLREASRDRFHQEIRMKQFPALFEVQHTALKEGALMSTLSGSGSSFFNLCLKEDAPSLAQKLQDRFPKFRVLELKFDNKGVVRDD
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA9_RAT
Sequence: MADAPGLIPIFLLGYLLSTECAVFLDRENATKILTRPKRYNSGKLEEFVQGNLERECIEERCSFEEAREVFENTEKTTEFWKQYVDGDQCESNPCLNGGICKDDINSYECWCQAGFEGRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGRVSVAYNSKKITRAETVFSNTDYGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQVILNGEIEAFCGGAIINEKWIVTAAHCLKPGDKIEVVAGEHNIDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSGYVSGWGKVFNKGRQASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAMKGKYGIYTKVSRYVNWIKEKTKLT
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEOC_ACTSZ
Sequence: MQPREIAKFIDHTALTTEKTEQDILKLCDEAVAHHFRSVCINSGYIPLAKQKLTGTGVKICTVVGFPLGANLSSVKAFEAQEAIKAGAQEVDMVINVGLIKSGKWDEVRSDIEQVLHACRGTLLKVILETCLLTKAEIVHACEICRDLNVGFVKTSTGFNKSGATVADVALMRQTVGENIGVKASGGIRDTQTTLAMINAGATRIGASAGIAIIQGLQDNNGGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCTR3_HUMAN
Sequence: MAWMLLLILIMVHPGSCALWVSQPPEIRTLEGSSAFLPCSFNASQGRLAIGSVTWFRDEVVPGKEVRNGTPEFRGRLAPLASSRFLHDHQAELHIRDVRGHDASIYVCRVEVLGLGVGTGNGTRLVVEKEHPQLGAGTVLLLRAGFYAVSFLSVAVGSTVYYQGKCLTWKGPRRQLPAVVPAPLPPPCGSSAHLLPPVPGG
What is the function of this protein?
Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1.  Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands.  It controls, for instance, NK cells cytotoxicity against tumor cells.  Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.
What are the official names of this protein?
Natural cytotoxicity triggering receptor 3, Activating natural killer receptor p30, Natural killer cell p30-related protein, NK-p30, NKp30.
What is the protein family that this protein belongs to?
Belongs to the natural cytotoxicity receptor (NCR) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: PSBF_GUITH
Sequence: MSKIKQPISYPIFTFRWLAIHGLAVPTVFFLGAITSMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: YD180_YEAST
Sequence: MVRLNHAASYFMPIFCSTRPHIVILSALFSISLFSLFYASSELLLHQYDDPLMFKPNSQDYFRTFLLGLFSPFLYYFLKTFLFNINQRFLILNLIVDFPINDVFMLLILIGLAYPQVQDHEGGTIKHKECSWHIIPRQAYIFGISWALGEFTICIIGNLFNYQEIADPNINSGFTHQESANTYCNNNDMSHNDDCGCSTEYRPNVVDRSDITLSKCIEVRNDSSSISNNVYSSEYHPIKPLRSSSSTYGSIRQQPHENKKQLHVPDNSQDDTIIMMNPIDNSLKLTTLDTGDLSFPIDEEQPILKKSFGYTWAVPNENTQNTTKSFTPIKRFIAFSTAYQLVTGLLLMILVVGSNIMLTIGESLILSMYFVYVRGHEGLFTPVVNYFGSRTISNFILCVIIPFISLNFLINTSIYLRRELDDWFNNSQGEFEDDDENTISKRVATNQEYQHPLSANYISMDSPDVINSSPGHFGMNSGQLLGNTTLYYGSLNGDDDDMTNDSALLRFCKKLVKNWRALARNDSFVLGVMVSWSLLVFVTGILSTVYI
What are the official names of this protein?
Uncharacterized membrane protein YDL180W.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: YIHY_ECOHS
Sequence: MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SELA_DESVH
Sequence: MNRLFRALPSVDALLTALTTPTHGHDTFADLPRALLRDLVNDFLDARREDIRQGRIDAPESLAAERLLPSLVQSVGRRSRAHFRRVLNGTGVVIHTNLGRSLLAPAATEAVAAACAHYSNLEFDLDTGERGSRYSHVEQLLCRVTGAEAGLVVNNNAAAVLLVLDTLCKGGEVVVSRGQLVEIGGSFRIPDVMEKSGATLREVGATNRTHLRDYENAINEKTVALLRVHTSNYRVVGFHKEVPLDELVALGRARDLPVIEDLGSGSFLDFTPWGLPGEPTVQSVVGAGPDVITFSGDKVLGGPQAGLIVGRRQWIDRIKRNPLNRALRIDKMTLAALEATLRLYLDPERARNEVPTLRMMTASPDELARRARRLAARLRKALGDAARVGTVPGVSRVGGGSFPERDLPTTLVEVAPASCTATVLKTRLLDTDPPLVGRLENDTFRLDPRTLDDVEFAPVATALRQALGL
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_CAUVC
Sequence: MSNVTVVSHPLVQHKLTKMRDKTTSTKTFRALMRETATLICYEVTRDLPMDEVQIETPVAPTKAYEIAGKKLVFAPILRTGLGMCEGMLDLVPSARVAHIGLYRDHETLEAVEYYFKAPEDIAGRLVIVVDPMLATGHSAIAAIARLKHYGVTNLRFVCLLAAQAGVDALREAHPDVPIWTAAIDQTLNDHGYIVPGLGDAGDRTFGTR
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ARI3A_MOUSE
Sequence: MKLQAVMETLIQRQQRARQELEARQAPPPPPPEPTGVRARTTMTDEDREPENARMHRTQMAALAAMRAAAAGLGHPSSPGGSEDGPPISGDEDTAREGTLSSPALHGSVLEGAGHAEGDRHLMDVGSDDDDTKSKWEEQELEELGEEEEEEEEEDDFEEEEEEEEGLGPPESASLGTAGLFTRKAPPAQAFRGDGGPRMLSGPERLGPGPAHPSHMASQMPPPDHGDWTFEEQFKQLYELDADPKRKEFLDDLFSFMQKRGTPVNRIPIMAKQVLDLFMLYVLVTEKGGLVEVINKKLWREITKGLNLPTSITSAAFTLRTQYMKYLYPYECERRGLSSPNELQAAIDSNRREGRRQSFGGSLFAYSPSGAHSMLPSPKLPVTPLGLAASTNGSSITPAPKIKKEEDSAIPITVPGRLPVSLAGHPVVAAQAAAVQAAAAQAAVAAQAAALEQLREKLESTEPPEKKMALVADEQQRLMQRAVQQSFLAMTAQLPMNIRINSQASESRQDSAVSLTSANGSNSISMSVEMNGIVYTGVLFAQPPPPTAPSAPGKGGVSSIGTNTTTGSRTGASGSTVSGGQVGLPGVSTPTMSSTSNNSLP
What is the function of this protein?
Transcription factor involved in B-cell differentiation.  Binds a VH promoter proximal site necessary for induced mu-heavy-chain transcription.  Binds the minor groove of a restricted ATC sequence that is sufficient for nuclear matrix association.  This sequence motif is present in matrix-associating regions (MARS) proximal to the promoter and flanking E mu.  Activates E mu-driven transcription by binding these sites.  May be involved in the control of cell cycle progression by the RB1/E2F1 pathway.
What are the official names of this protein?
AT-rich interactive domain-containing protein 3A, ARID domain-containing protein 3A, B-cell regulator of IgH transcription, Bright, Dead ringer-like protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between nucleus and cytoplasm.
Protein: MYB30_ARATH
Sequence: MVRPPCCDKGGVKKGPWTPEEDIILVTYIQEHGPGNWRAVPTNTGLLRCSKSCRLRWTNYLRPGIKRGNFTEHEEKMIVHLQALLGNRWAAIASYLPQRTDNDIKNYWNTHLKKKLNKVNQDSHQELDRSSLSSSPSSSSANSNSNISRGQWERRLQTDIHLAKKALSEALSPAVAPIITSTVTTTSSSAESRRSTSSASGFLRTQETSTTYASSTENIAKLLKGWVKNSPKTQNSADQIASTEVKEVIKSDDGKECAGAFQSFSEFDHSYQQAGVSPDHETKPDITGCCSNQSQWSLFEKWLFEDSGGQIGDILLDENTNFF
What is the function of this protein?
Transcription factor that binds specifically to the DNA sequence 5'-AACAAAC-3' (PubMed:19170933).  Acts as a positive regulator of hypersensitive cell death (PubMed:10571865, PubMed:12119395).  Acts as a positive regulator of salicylic acid synthesis (PubMed:16730712).  Regulates very-long-chain fatty acid biosynthesis (PubMed:18326828).  Acts cooperatively with BZR2 to promote expression of a subset of brassinosteroids target genes (PubMed:19170933).  Transcriptional activity and hypersensitive response control negatively regulated by PLA2-ALPHA (PubMed:20696912).  Involved in the regulation of abscisic acid (ABA) signaling (PubMed:22814374).  Increased levels of MYB30 can accelerate flowering both in long and short days through the regulation of FT (PubMed:24587042).
What are the official names of this protein?
Transcription factor MYB30, Myb-related protein 30, AtMYB30.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMO_BRADU
Sequence: MDRAPRISFTSLGCPKALVDSERIITRLRAEGYELARKHDGADIVIVNTCGFLDSAKQESLSAIGEAMAENGKVIVTGCMGAEPEQIEQAYPGVLSITGPQQYESVLDAVHRALPPAHNPHLDLVPPQGIKLTPRHYAYLKISEGCNNRCTFCIIPKLRGDLVSRPANDVLREAERLVGAGVKELLVISQDTSAYGVDLKYAESPWKDRQVRAKFLDLARELGELGAWVRLQYVYPYPHVDEVIALMTQGTVLPYLDIPFQHASPEVLKAMKRPAAQDKTLARIKRWREECPDLALRSTFIVGFPGETDADFAYLLDWLDEAEIDRLGCFKYEPVAGATSNAIANPVPEEVKQERYNALMARQQKISARRLKRKVGTRQQIIIDEVGPTVARGRSKADAPEIDGAVYLSSRRPLRVGEIVTAKIERADQYDLHGSVAGF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDH_PROMH
Sequence: MKALSKLKAQPGIWMTDVPVPELGHNDVMIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYIGEIVAIGQEVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNIPDELAAIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAICKHVGARHVVITDVNEYRLDLAKKMGVTRAVNVSKENLTDVMKELGMTEGFDVGLEMSGAPPAFRTMLSTMNHGGRIALLGIPPSDMAIDWGQVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHQFPIDEFQKGFDIMRSGQSGKVILDWQ
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_SALTI
Sequence: MQPDLHCRTLAAHTLKHFRALSPLTHCMTNDVVQTFTANTLLALGASPAMVIDPVEARPFAAIANALLINVGTLTASRADAMRAAVESAYDAKTPWTLDPVAVGALEFRRRFCLDLLSLRPAAIRGNASEILALSGMALGGRGVDTTEAALAALPAAQALARQIDCIVVVTGEIDYVTNGQRTLSIPGGDPLMTRIVGTGCALSAVVAASCALPGAALDNVASACCWMKLAGQVAAERSEGPGSFIPAFLDALYHLDMEAANATN
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: Y1283_METMP
Sequence: MSVALKKFFSKRGQLSLEFSVLVLAVITAAILLGYHLIVSSKAVQESNIDTINNTHNTAIDALSEVS
What are the official names of this protein?
UPF0333 protein MMP1283.
What is the protein family that this protein belongs to?
Belongs to the UPF0333 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MURA_PARDP
Sequence: MDQIIVRGNGPLKGEIPITGAKNACLALMPATLLTDQPLTLTNAPRLSDIRTMTALLQSLGAEVASLQDGQVLALSSHDLTSHRADYDIVRKMRASILVLGPMLARDGHAVVSLPGGCAIGARPVDLHLRALEAMGADLDLREGYVHAKAPSGGLRGAVIDFPLVSVGATENALMAATLARGTTVINNAAREPEIVDLAECLRRMGAQIEGEGTSTITVEGVQALGGATHPVVTDRIELGTYMLAPAICGGEVECLGGRIDLVAAFCEKLDEAGIEVVETGRGLKVSRKNGRVRAVDVVTEPFPGFPTDLQAQMMALLCTAEGTSVLEEKIFENRFMHAPELARMGARIEVHGGHATVHGVEKLRGAPVMATDLRASVSLILAGLAAEGETIVSRVYHLDRGYEKVVRKLRGVGADIERIKEVADG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_MYCPN
Sequence: MQAKPTTAVKQKQNFGQRLFTLLRNRDFMISFLITVVLLVLFRVLAIIPLPGIQVNQTGLDQNSNDFFSLFNLLGGGGLNQLSLFAVGISPYISAQIVMQLLSTDLIPPLSKLVNSGEVGRRKIEMITRIITLPFALVQSFAVIQIATNSGGGSSPITLKNNGSDFVAFYIIAMTAGTYLSVFLGDTISKKGIGNGITLLILSGILAQLPEGFIAAYSVLSGVVVTINATLTTAISFFIYFMAFVTLLFATTFITQETRKIPIQQSGQGLVTESSALPYLPIKVNSAGVIPVIFASSIMSIPVTIAQFQPQTESRWFVEDYLSLSKPTGIVLYGILVILFSFFYSYIQINPERLAKNFEKSGRFIPGIRPGKDTEKHIARVLVRINFIGAPFLTVIAIIPYIVSALIHLPNSLSLGGTGIIIIVTAVVEFMSALRSAATATNYQQLRRNLAIEVQKTAQQDKEEQLRAETPGIGNLW
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMC_HAEIG
Sequence: MTFSVQHAEIHFNQNHIPVSDQFDDVYFSNENGLAETDYVFLQGNQLWERWITHKEANFVIAETGFGTGLNFFAATKLFRKFRQQHENHPLKRLNFISFEKYPLKITALSQAHLACPQFEDLSAHLQRYWPSLILGCHRIHFEETTLDLWFGDVSENLPQLGDYMNERIDAWFLDGFAPSKNPEMWNDDLYNLIFRFTKPNGTFATFTAASAVRKGLESAGFNVTKRKGFGKKRECLSGLKIQSKSTALSTPWYLAQPAKMEKQDFAIIGGGIASLCAAISLVKRGAKVTIYCEDAALALNASGNKQGAFYPQLSDDNVLTVDFYLHAFSYGRQLLDWAIEQNIAFEHEFCGVALCAYNEKSAVKLTKISQLGLPNEIFQMLSAEQLSEKVGLPLNCEGGWIEQGAWLAPRQFVQNAFSFLEKQGVIIKTAQKITALSQEEKGWELKNMQGQKYCHEVVILANGHKITDFVQTEKLPLYPIRGQVSQIPTSENLLKLKSVLCYDGYLTPANQLKTSHCIGASHVRDNVDRHFSEQEQQENQQKLQQNIAQPWTQDVNTSDNLARVGIRCSVRDLAPMVGNVPHFEQQQAGYYNLFNLRRRKQPIQSAVNFQNIFLIAALGSRGLTSAPLLGETLASILYGEPLPISEGILHNLSANRAWVKKWLKGSKVE
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RET5_HUMAN
Sequence: MPPNLTGYYRFVSQKNMEDYLQALNISLAVRKIALLLKPDKEIEHQGNHMTVRTLSTFRNYTVQFDVGVEFEEDLRSVDGRKCQTIVTWEEEHLVCVQKGEVPNRGWRHWLEGEMLYLELTARDAVCEQVFRKVR
What is the function of this protein?
Intracellular transport of retinol.
What are the official names of this protein?
Retinol-binding protein 5, Cellular retinol-binding protein III, CRBP-III, HRBPiso.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3MGH_DESRM
Sequence: MQPLPVEFYARQTTLVAKELLGTLLVHNSDEGITVGKIVETEAYLQGDPACHAARRMTPRNSVMFGPPGRAYVYFTYGMHYCFNVVTASEGVGEAVLIRAVEPLKGLELMRKRRGRERLHELCAGPARLVQAFGITKEHNTKELTSGPLYIAVSSEPSPEIHTTTRIGIKEGADLPLRFYIKDNKFISKK
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: GLGS_ECOLC
Sequence: MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQARELELEH
What is the function of this protein?
Major determinant of cell surface composition.  Negatively regulates motility, adhesion and synthesis of biofilm exopolysaccharides.
What are the official names of this protein?
Surface composition regulator.
What is the protein family that this protein belongs to?
Belongs to the GlgS family.