PharMolix/UniProtQA huggingface dataset:
Protein: FABZ_PSEMY
Sequence: MMDINEIREYLPHRYPFLLVDRVVDLDVEGKQIRAYKNVSINEPFFNGHFPEHPIMPGVLIIEAMAQAAGILGFKMMGVKPADGTLYYFVGSDKLRFRSPVLPGDQLTLEAKYLSDRRSIWKFECRATVDGKEVCSAEIICAERKL
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FSP1_BOVIN
Sequence: MGSQVSMDAGAVHVVIVGGGFGGIAAASQLQALNIPFVLVDMKDSFHHNVAALRASVESGFAKKTFISYSVTFKENFRQGLVVEIDLKNQTVLLEDGQALPFSHLILATGSTGLFPGKFNQVSSQQMAIQAYEDMVTQVQRSQSIVVVGGGSAGVEMAAEIKTEYPEKEVTLIHSKMALADTELLPCVRQEVKEILLRKGVQLLLSERVSNLEALPVNERRECIKVQTDKGTEVDANLVIVCNGIKINSAAYRSAFGDRLASNGALRVNEYLQVEGYSHIYAIGDCADVREPKMAYHASLHANVAVANIVNSMKQRPLKTYKPGSLTFLLAMGRNDGVGQISGFYVGRLMVRLAKSRDLLVSTSWKTMKQSPP
What is the function of this protein?
A NAD(P)H-dependent oxidoreductase that acts as a key inhibitor of ferroptosis.  At the plasma membrane, catalyzes reduction of coenzyme Q/ubiquinone-10 to ubiquinol-10, a lipophilic radical-trapping antioxidant that prevents lipid oxidative damage and consequently ferroptosis.  Acts in parallel to GPX4 to suppress phospholipid peroxidation and ferroptosis.  This anti-ferroptotic function is independent of cellular glutathione levels.  Also acts as a potent radical-trapping antioxidant by mediating warfarin-resistant vitamin K reduction in the canonical vitamin K cycle: catalyzes NAD(P)H-dependent reduction of vitamin K (phylloquinone, menaquinone-4 and menadione) to hydroquinone forms.  Hydroquinones act as potent radical-trapping antioxidants inhibitor of phospholipid peroxidation and ferroptosis.  May play a role in mitochondrial stress signaling.  Upon oxidative stress, associates with the lipid peroxidation end product 4-hydroxy-2-nonenal (HNE) forming a lipid adduct devoid of oxidoreductase activity, which then translocates from mitochondria into the nucleus triggering DNA damage and cell death.
What are the official names of this protein?
Ferroptosis suppressor protein 1, FSP1, Apoptosis-inducing factor homologous mitochondrion-associated inducer of death, AMID, p53-responsive gene 3 protein.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase family.
What are the subcellular locations of this protein?
Lipid droplet. Cell membrane; Lipid-anchor. Cytoplasm. Mitochondrion membrane. Nucleus.
Protein: PUG1_YEAST
Sequence: MSTTDSGFVLYHYTPSKAAAIVFVVLFIIMTVIFAVQTLYAARKSSKALKNNPFESSDDKVDSLEDAEYKQLKITPTVFAFIPFFTGCIMEAVGYIGRALSSSNPERTTPYIIQSVLLLVAPALIAATIYMIFGRLLHVMRCQSLILISARFGTTFFVVGDVFSFFLQAAGGGLMSKAGSTKTGSGLITAGLFVQVIFFGFFIINEIRFTVNVKRRCLFYEDISRKWIFVNATLLLSSMLILLRSIVRIVEFIQGFNGYIISHEYFIYVFDAVPMLLVIIAFSVGSFFGNVFDVIKECQTLSN
What is the function of this protein?
Involved in inducible protoporphyrin IX influx and heme efflux.
What are the official names of this protein?
Protoporphyrin uptake protein 1.
What is the protein family that this protein belongs to?
Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YBHG_ECOK1
Sequence: MMKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQATLKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPNKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE
What are the official names of this protein?
UPF0194 membrane protein YbhG.
What is the protein family that this protein belongs to?
Belongs to the UPF0194 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: F166B_MOUSE
Sequence: MAVVNTSIPGLSGENPHYIPGYTGHCPLLRFSMGQTYGQVTGQLLRGPPGLAWPPAHRTLLPPIQSPRSPVISKGRLPPRRGHERLSSSIIPGYTGFIPRAQFIFAKNCNQVWAEAMSEFTRRHGEQESHQLPDGAKGEREVEEDQLREAEEPPLKQELAHASPYSMDDTDPHKFFMSGFTGYVPRARFLFGSSFPVLTNQALQEFGQMCSRGRAHKDPKPLSPLPRPTFQNLGLLPHYGGYVPGYKFQFGGTFGHLTHDALGLSITQKQLPA
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.
What are the official names of this protein?
Protein FAM166B.
What is the protein family that this protein belongs to?
Belongs to the UPF0605 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: TIP21_ARATH
Sequence: MAGVAFGSFDDSFSLASLRAYLAEFISTLLFVFAGVGSAIAYAKLTSDAALDTPGLVAIAVCHGFALFVAVAIGANISGGHVNPAVTFGLAVGGQITVITGVFYWIAQLLGSTAACFLLKYVTGGLAVPTHSVAAGLGSIEGVVMEIIITFALVYTVYATAADPKKGSLGTIAPLAIGLIVGANILAAGPFSGGSMNPARSFGPAVAAGDFSGHWVYWVGPLIGGGLAGLIYGNVFMGSSEHVPLASADF
What is the function of this protein?
Aquaporin required to facilitate the transport of water from the vacuolar compartment to the cytoplasm.  Does not promote glycerol permeability.  Its function is impaired by Hg(2+).  Transports urea in yeast cells and Xenopus laevis oocytes in a pH-independent manner.  Transports methylammonium or ammonium in yeast cells and Xenopus laevis oocytes, preferentially at high medium pH.  May participate in vacuolar compartmentation and detoxification of ammonium.
What are the official names of this protein?
Aquaporin TIP2-1, Delta-tonoplast intrinsic protein, Delta-TIP, Tonoplast intrinsic protein 2-1, AtTIP2;1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. TIP (TC 1.A.8.10) subfamily.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast. It is specifically located in the tonoplast of protein storage vacuoles (PSV) (By similarity).
Protein: Y1970_STAS1
Sequence: MFEAIIYNISVTVAGIYLFHRLQYSENRIMVFSKEYVTVLMTIVALLLSAYPVPIFNEYTLYLSFVPILFLGRYTNMFYTVLSAFIVGLVNVLIGDYTIITAMIFIVIAGIIGAIGPFLKQSDIISLQILNVIALVIFAILSLISPYYEITEVLFLIPISFVLTITSSITFVDIWHFFSLVNRYENEDKVDYLTGLGNVKEFDRHLNETARLSEENNQSLGLLLIDIDGFKDVNDMYSHKSGDAVLRQVAQLLKNYVPQQFSIYRNGGEEFSIVLYDYTLDQCVKLSESIRGGVEQSTFHLPNKEVIKLSVSIGVGYLTTDDYKSQRKVFKIADDMLHMAKNEGRNQVMFNPIVKL
What are the official names of this protein?
Uncharacterized membrane protein SSP1970.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GATA_RUTMC
Sequence: MHTKTIVELAQGFKDKDFSCVELTQYYLNRIDQSDLNAFITVTDELALAQAQVADDKIASGNANILTGIPYAHKDIFCTKGVKTSAGSRMLDTFVSPYDATVSQKLNQVNLVMLGKTNMDEFAMGSSNENSFYGAVKNPWNYLKIPGGSSGGSAASVAGGLSCFATGTDTGGSIRQPASLCGITGIKPTYGRISRYGMIAYASSLDQAGPMTKTAQDAAIVLNVMAGFDEKDSTSVEQKVPDYTTHLNDSIKGLIIGLPKEFFSSGLDDEVANNIMAAVKEFEAMGAIVKEVSLPNLAYAIPVYYIVAPCECSSNLSRLDGVRYGYRAKNVKNLEDLYLRSRSEGFGEEVKRRIMIGAYALSAGYYDAYYLKAQKVRHLISDDFKKVFEQIDVIMGPVSPTTAFDLGSVKDPVSMYLADIYTLSANLAGLPGMSIPAGFAQNLPVGLQLIGNFWSESRLLNIAHQFQLQTDWHLKTPQEC
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: ISPG_SHISS
Sequence: MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQRVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: YLY6_SCHPO
Sequence: MSIKLGYLFKLPSYKTSSISPEVIVDLEKFLNLCEGSCSQCNTPFCVDVGPRNAIIQLPNGADVLNLNPNFQAIFECCSKNSLTGVQIFGMYNDGTYELRSFCPVHGVNEDPANGSGAGSVGVFFALNNPSIISSDFAHLLFNQGKILGRNALIRVAIKLSANGLYDIHVGGGSKICISGTAEI
What are the official names of this protein?
Uncharacterized isomerase C186.06.
What is the protein family that this protein belongs to?
Belongs to the PhzF family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HIS6_METS5
Sequence: MTTRRIIACLDVKDGKVVKGVRFLDLKLKGDPAELASRYEEEGADEIVFLDISATVEGRKTLLEKVRETASVLSIPLTVGGGVRTVEDVSNLLSNGADKVSLNTVAAENPSVVSMASREFGAQAVVVAIDAKRVGNGWRVFVRSGTKDTGLDAVDWAKRVEEMGAGEILLTSIDRDGTRDGYDLELTKAVVRATKVPVIASGGAGKPDHFLSVFRQAGADAALAAGIFHDGVIRIRELKDYLKDAGIEVRT
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_BRASO
Sequence: MSFNTFGHMFRVTTFGESHGVAIGCVVDGCPPRIPLEAAEIQTDLDRRRPGQSRFTTQRQEPDQVKILSGVMADPDTGAQVTTGTPIALLIENTDQRSKDYSEIKDKFRPGHADFTYEAKYGLRDYRGGGRSSARETATRVAAGAIARKIIAGVKVRGALVQMGPHKIDRDKWDWDEIARNPFFCPDKDKAAFFEDYLDGIRKSGSSIGAVLEITAEGVPAGLGAPLYGKLDADLAAAMMSINAVKGVEIGAGFGAAELTGEANADEMRSANDGTRFLSNHAGGILGGIATGQPIVVRFAVKPTSSILTPRQTVDRAGHETEILTKGRHDPCVGIRAVPVGEAMMACVLADHLLRHRGQVG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: APT_BEII9
Sequence: MNKPIDLKSAIRTISNYPKPGIEFRDITTLLGDARAFRRAVDELVQPWAGTKVDKIAGMEARGFILGGAVAHQLSAGFVPIRKKGKLPHTTVSIAYSLEYGLDEMEIHADAVVKGEKVILVDDLIATGGTATGAVGLLQKLGAEVIAACFVIDLPDLGGAKKIEALGVPVRSLISFEGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSI_ACTP7
Sequence: MSDKKTKGLEWQEKPLSDNERLKTDSNFLRGTILDDLKDGLTGGFKGDNFQLIRFHGMYEQDDRDIRAERLEEKLEPLKFMLLRCRLPGGIIKPYQWIEIDKFAREHTRYQSIRLTNRQTFQYHGVPKGKLQPMHRLLHSIGLDSIATAADMNRNVLCTSNPIESELHQQAYEFAKKISEHLLPRSRGYLDVWVDGKKVESSDDLLKIEDEPILGKTYLPRKFKTAVAIPPLNDVDVYANDLNFIAIQDENGQLCGFNVLVGGGLSFEHGNTKTYPNVAYSLGFVPLEHTLAAAEGVVKTQRDFGNRSDRKNARVRYTIQNMTLDGFRAEVERCMNIKFEPTRPYEFTERGDRIGWVKGIDNNWHLTLFIESGRITDKPEKPLMTGVLELAKVHKGDFRITANQNLIVANVAEQDKAQIEAIARQYGLIQEISKLRENAMSCVSLPTCPLAMAEAERVLPDFISELDKVLSKHNVADESIITRITGCPNGCGRAMLAEIGLVGKAIGRYNLHIGGDRAGLRISRLYKENITLQEIVNEIDQLVARWATERQTNEAFGDFVIRSNIIAPVVNAHIDFWDATKIIPTTII
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: ENGB_SHEAM
Sequence: MNQTRIDFRQAKFLISAPDIAHLDKHLPGDVGVEIAFAGRSNAGKSSALNALTEQKSLARTSKTPGRTQLINVFELDAQRRLVDLPGYGFAKVPLEMKHKWQNALGEYLQKRACLSGVVVLMDIRHPLKDLDRQMIEWSVASEIPVLALLTKADKLGQSEKMKTVNAVRKELAEFGDWVSVEPFSALKGTGKPKVLAILDAWCHPDWLVEELEQAED
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RS13_BORPD
Sequence: MARIAGINIPPQQHAEIGLTAIFGIGRTRARKICEAANVPLSKKVKDLTDAELERIREHVGVFTVEGDLRREVQLSIKRLIDLGTYRGMRHKRGLPVRGQRTRTNARTRKGPRRAAASLKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: HPRK_STAA3
Sequence: MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).  The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc. ) in the growth medium.  Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: RIMM_PSEA8
Sequence: MPTPADDLVVIGKIVSVYGIRGEVKVYSFTDPLDNLLDYRRWTLRRDGEIRQAELVRGRLHGKVLAAKLKGLDDREEARTFTGYEICIPRSELPSLEEGEYYWHQLEGLKVIDQGGQLLGVIDHLLETGANDVMVVKPCAGSLDDRERLLPYTGQCVLSIDLAAGEMRVDWDADF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM24_CANTT
Sequence: MINTKIGRPCVRLHQLNFIRSITINQQPSSTISTEQLTKTTTIPSNIQQVEELTNSRTLEAPEFKTLGNSGSSTTSSSSSSILSINLPPSVPIYLKRGSLLSIYGIKQDITSINSVRSSLEFPLFWKKLIYGIDSNKGYQRLISTSPFSILVSSQSRRGGSIFSKNNGDKSFVNLILDGGTDWAILKNDSIQAYSGNSLNLNIYKLPNYISKKLSKKLGFGNKKFKTGLISWINRKIGYILISGRGNVGLIGNGNIYNLNLIKNEEILINKENLLGITVNGPYDLQNCIIKYQFPLKDQSIIDSNTSDVIIEKPKLYEPNSWGMIKYRFDQFNKSFKKIFQSIFKYSSDVKESGFNYLVGNQEFIKIIGPRNILIQSNVDNSFIIPSIKRSDKIVTPVKSNDNTEVKKSTTTGDYLNYVTIEPGKGAVFKSTPDFKDTVDQIDNKSK
What are the official names of this protein?
Altered inheritance of mitochondria protein 24, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the AIM24 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FMT_ACIB5
Sequence: MKIIFAGTPEFAATALAALLKTSHEIIAVYTQPDRKAGRGQKLTPSPVKQLALEHNIPVYQPLHFKASTEEGLAAQQELAALGADVMVVAAYGLILPQAVLDTPKYGCLNIHGSLLPRWRGAAPIQRAIATGDDETGITIMQMAAGLDTGDMMYKTYCPIASEDTSATLHDKLAAQGATAICAVLESEETLQKYLAEREVQDESLTVYAHKLVKSEARIDWSMNAVQVDRNIRAFNPWPVAFIQLDENNALRVWNSIISSQSKVNAQAGEIIAIDKQGVHVACGENTFICLTSVQWPGGKALNAQQIAQTQKLHVGQILP
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: BR1C_LITBE
Sequence: FLPFIAGVAAKFLPKIFCAISKKC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus.
What are the official names of this protein?
Brevinin-1Bc.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: Y119_MYCGE
Sequence: MEKVAFKMEHISKSFDNGKIKANVDVSLVVYENTVHTILGENGAGKSTLTSILFGLYKPDSGKIFIGEKQVNFKSSKDAVKHKIGMVHQHFKLIENYTVLDNIILGNESRFGFLPLINRKVSEAKIKTIMEKYGIFVDLKQKVSNLTVGQQQRVEILKVLFRDSNILIFDEPTAVLSDLEIQNFLKIIANFKKLGKTIVLISHKLNEIKQVADTATVLRLGKVVGSFDVKTTPVDKIALLMMGKELKQTKNTTDFVAKDEPVLKVQNLNLFLNKSLAYKFLVRCNNIHKAQQIKKNKPLKDLWIISFLNKLTTSNKTPKLVKGLINKLGLSYQENTDETISFAIHKGEIFAIAGVEGNGQSQLVNLICGIEKAASNKLIFNNIDISRWSIRKRINAGISFVLEDRHKYGLILDQTVRFNTVNNQINNRPFSSWNFLKPMEIALYSNTIIKKFDVRGSAEGSAVVRRLSGGNQQKLIIGREMTKQNDLLVLAQVTRGLDIGAIAFIHENILLAKANNKAILLVSYELDEILALADTVAVINKGRIVGMGKRDLMDRQSIGRLIMQ
What is the function of this protein?
Part of the ABC transporter complex involved in carbohydrates import.  Probably responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Putative carbohydrate transport ATP-binding protein MG119.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RL35_RHILO
Sequence: MPKMKTKSAAKKRFKITGTGKVLSAAAGKRHGMIKRSNKFIRNARGTMVLAEPDGKKVIKNFLPNGL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RS15_FRATN
Sequence: MLTAQDKQKIIKENQLAEGDTGSPEVQVALLTARINDLQGHFETHKKDNHSRRGLLRLVSQRRKLLDYLHDKDVERYRSLIKKLNIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: CRGB_RAT
Sequence: MGKITFFEDRGFQGRCYECSSDCPNLQTYFSRCNSVRVDSGCWMLYERPNYQGHQYFLRRGDYPDYQQWMGFSDSIRSCRLIPQHSGTYRMRIYERDDFRGQMSEITDDCLSLQDRFHLSEIHSLNVMEGCWVLYEMPSYRGRQYLLRPGEYRRYLDWGAANAKVGSFRRVMDFY
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin B, Gamma-B-crystallin, Gamma-crystallin 1-2.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: Y879_BACCR
Sequence: MNIWLNMLTTTGLGAIIGGYTNHLAIKMLFRPHRPIYIGKFQVPFTPGLIPKRRDELAVQLGKMVVEHLLTPEGIGKKLTNEEFQKGLIHWAQVEVDKVITNEQSLRHMLEKWNVAHVEEEATRKIEHVITEKIHAFLAEYYTYTWEQALPHSVNEKVENAIPNVSAFILERGISFFESEEGKARLSKMIDDFFASRGTLLNLVGMFLGNVSVVDRVQPEVIKFLGQDATKQLLTDVLQKEWEKLKGRDVKELEAFVEKEMIVSSVLSAVKVEETVSKFLNQSVQQVCEPVRETIIEKVVPSAVAKGLKWGTENVESILNNLHLAEIVQQEVSTFSTERLEDLVLSITKNELKMITYLGALLGGMIGLVQGLLLLFLR
What are the official names of this protein?
UPF0754 membrane protein BC_0879.
What is the protein family that this protein belongs to?
Belongs to the UPF0754 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NUAK1_HUMAN
Sequence: MEGAAAPVAGDRPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEVMLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGVVGPALPSTFKMEQDLCRTGVLLPSSPEAEVPGKLSPKQSATMPKKGILKKTQQRESGYYSSPERSESSELLDSNDVMGSSIPSPSPPDPARVTSHSLSCRRKGILKHSSKYSAGTMDPALVSPEMPTLESLSEPGVPAEGLSRSYSRPSSVISDDSVLSSDSFDLLDLQENRPARQRIRSCVSAENFLQIQDFEGLQNRPRPQYLKRYRNRLADSSFSLLTDMDDVTQVYKQALEICSKLN
What is the function of this protein?
Serine/threonine-protein kinase involved in various processes such as cell adhesion, regulation of cell ploidy and senescence, cell proliferation and tumor progression.  Phosphorylates ATM, CASP6, LATS1, PPP1R12A and p53/TP53.  Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1, thereby controlling its stability.  Controls cell adhesion by regulating activity of the myosin protein phosphatase 1 (PP1) complex.  Acts by mediating phosphorylation of PPP1R12A subunit of myosin PP1: phosphorylated PPP1R12A then interacts with 14-3-3, leading to reduced dephosphorylation of myosin MLC2 by myosin PP1.  May be involved in DNA damage response: phosphorylates p53/TP53 at 'Ser-15' and 'Ser-392' and is recruited to the CDKN1A/WAF1 promoter to participate in transcription activation by p53/TP53.  May also act as a tumor malignancy-associated factor by promoting tumor invasion and metastasis under regulation and phosphorylation by AKT1.  Suppresses Fas-induced apoptosis by mediating phosphorylation of CASP6, thereby suppressing the activation of the caspase and the subsequent cleavage of CFLAR.  Regulates UV radiation-induced DNA damage response mediated by CDKN1A.  In association with STK11, phosphorylates CDKN1A in response to UV radiation and contributes to its degradation which is necessary for optimal DNA repair (PubMed:25329316).
What are the official names of this protein?
NUAK family SNF1-like kinase 1, AMPK-related protein kinase 5, ARK5, Omphalocele kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.