PharMolix/UniProtQA huggingface dataset:
Protein: MURC_VIBCH
Sequence: MTIKHTQDLAQIRAMVPEMRRVKAIHFIGIGGAGMSGIAEVLLNEGYQISGSDLAANAVTDRLADKGATIFIGHEAHNVAHASVVVVSTAINEQNPEIQAAREKRIPIVRRAEMLAELMRFRHGIAVAGTHGKTTTTALVTQIYSEAGLDPTFVNGGLVKSAGTNARLGSSRILIAEADESDASFLHLQPMVTIVTNIEADHMDTYGGDFENLKQTFIDFLHNLPFYGQAILCIDDPVIRELIPRVSRQVITYGFSEDADVRIENYRQNGQQGQFTVVRKGKANLDITLNIPGRHNALNAAAAIAVATEDDIRDEAILRAMANTQGTGRRFDHLGEFETGNGVAMLVDDYGHHPTEVDVTIKAARNGWAEKRLVMIFQPHRYTRTRDLYDDFANVLEQVDVLIMLDVYAAGEKPIAGADGRSLCRTIRSRGKIDPIFVPDSQTLPSVLANILQDGDLVLTQGAGDVGKVARHLAALELNIGRMQQI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URAD_HALVD
Sequence: MHELTLQQVNRLDDDSFVDAFGEIYEHSPWVAERARSSRPFSSVDELRSAMKRAVEDASREKQLQLLRAHPDLGERTEMTDASEAEQASAELDSLSRSQYETFQRLNETYRERFGFPFVMAVKDENPDAIAAAMERRVDHSESTEFRTALDEVHTIAELRLAERFSSE
What is the function of this protein?
Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.
What are the official names of this protein?
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, OHCU decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the OHCU decarboxylase family.
Protein: TGAL6_ORYSJ
Sequence: MELYPGYLEDHFNIHKLSISSASPPEYMTSASTQFAAPVRMGAYDRPPPVGMWSHEQFKVDNGQATSASTIMEAEMKFENRLEEIPQVVLEEGRNVDQEASKPPDKVLRRLAQNREAARKSRLRKKAYIQQLETSRLKLAQLEQELQRARQQAVYANGSLREPNLGFTGPIDPGALGFEIKYSHWVDEQNRNTGELRNALLQGQTTDQDLELKLLVEAGLDNYNRLFEMKEEAANSDVFYIMSGMWKTPTERFFLWIGGFRPSEVLKNLRPQLEPLTDKQVVEVGGLQQTSMQVEDALSQGMDKLKQTIADSLTAADPFDSPEAYMVHMANAVEQLRSLVQFVTQADHLRQQTLQEMHRILTTRQAARGLLALGDYFQRFRALSSLWAARPRDSGIS
What is the function of this protein?
Transcriptional regulator involved in defense response.
What are the official names of this protein?
Transcription factor TGAL6, bZIP transcription factor 37, OsbZIP37.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: XPP1_BOVIN
Sequence: MAPKITSELLRQLRQAMRNLEYVTEPIQAYIIPSGDAHQSEYIAPCDCRRAFVSGFDGSAGTAIVTEEHAAMWTDGRYFLQAAKQMDSNWTLMKMGLKDTPTQEDWLVSVLPEGSRVGVDPLIIPTDYWKKMAKVLRSAGHHLIPVKDNLVDKIWTDRPERPCKPLITLGLDYTGISWKDKVADLRLKMAERNVVWFVVTALDEIAWLFNLRGSDVEHNPVFFSYAILGLETIMLFIDGDRIDAPIVKEHLLLDLGLEAEYRIQVLPYKSILSELKILCASLSPREKVWVSDKASYAVSEAIPKDHRCCMPYTPICIAKAVKNSAESEGMRRAHIKDAVALCELFNWLEKEVPKGGVTEISAANKAEEFRRQQADFVDLSFPTISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMHFGTPTAYEKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTGHGVGSFLNVHEGPCGISYKTFSDEPLEAGMIVTDEPGYYEDGAFGIRIENVVLVVPVKTKYNFNNRGSLTFEPLTLVPIQTKMIDVDSLTDKECDWLNSYHLTCRDVIGKELQKQGRQEALEWLIRETQPISKQP
What is the function of this protein?
Metalloaminopeptidase that catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro.  Contributes to the degradation of bradykinin.
What are the official names of this protein?
Xaa-Pro aminopeptidase 1, Aminoacylproline aminopeptidase, Cytosolic aminopeptidase P, Soluble aminopeptidase P, sAmp, X-Pro aminopeptidase 1, X-prolyl aminopeptidase 1, soluble.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFKA2_NOSS1
Sequence: MRKRIGILTSGGDCPGLNCVIRAVVSHATLTYDWEVLGIPYATQGLRERQAIALNMHGWDLRGIDPLLNMGGTILGTINKGDTLAHVDEMLASYQALALDALIVIGGDGSLGILHELASRGNWNLVAIPKTIDNDVALTERAVGFDTAVNTIVDALNRLTFTAASHDRVMIVEVMGRSAGHLALHAGIAGGADVILIPEISYTISGLCQHIAELRDRWQRKFAIVVVAEGAKLCLEDVQENIASSCAPSKCGRGQYIADQIAQCSKNLIDTRVSVLGHIQRGGIPSALDRLTATVFGKTAVDLIAQGKFGQMVAWQNGEAIPVPIQDVVAQSPLHVNPQGSLVQSARCLGIYVGEKT
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase 2, ATP-PFK 2, Phosphofructokinase 2, Phosphohexokinase 2.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF11_SYMTH
Sequence: MARSDMIEVDGVIVEPRSNGFFTVRLDLENQPEVIAHLGGKLRRHYIRVVPGDRVTVELSPYDLTRGRIVYRYRH
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MP704_ORYSJ
Sequence: MGSLGEVVEHGVSKDMLPFDGHPDPVVDELNRLENLLREKDRELGHAYSEIKGLKVTEALKDKAIAELTKELKKQDEKLSSLEKQLEQKNLDVKRLSNERKEALSAQFAAEATLRRIHSSQKDEEVVPFDAIIAPLESDIKAYRHEIALLQDDKKALERHLKLKEAALVEAGNILRSALERALIVEDVQNQNIELKKQMEIYHEENKLLEKSNRQQVLDIERLTHTIAELEESILSTGDVANAVRFYQNQAAKLNEEKRTLERELARAKVYVNRVASTTANEWKDDADKLMPVKRWLEERRLLQGEIQRLRDKIAMAEKSAKAEAQLNDKLRRKLKALEDDMRNESSNTSASNKDNATSKQATPKRSSSQPRRPIISADGADKRRPASQPRASVSGKVLNKQPGSETEAAEKNRHAAAKRFDSPRSAKSVAAGGRGERPVRSHLWAHRSKVADDAGKENKEQNPNYKAHLGDSHADGDCGVQCSEHEEAMDLRKLDEGKADDSDAVKSTKDSCEI
What is the function of this protein?
Plant-specific protein that interact with microtubules.
What are the official names of this protein?
Microtubule-associated protein 70-4, AtMAP70-4, 70 kDa microtubule-associated protein 4.
What is the protein family that this protein belongs to?
Belongs to the MAP70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated to microtubules.
Protein: LUKL1_STAAW
Sequence: MIKQLYKNITICTLALSTTFTVLPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKNKMPVTVSEGFNPEFLAVMSHDKKDEGKSKFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHNVKFVKVLNDNEKK
What are the official names of this protein?
Uncharacterized leukocidin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: RNFA_PHOLL
Sequence: MTDYFLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGFATTFVMTLASVCSWLVNTFILLPLDLIYLRTLSFILVIAVVVQFTELVVRKTSPTLYRLLGIFLPLITTNCAVLGVALLNINQSHDFLQSAIYGFGAAAGFSLVMVLFAAIRERLAVADVPAPFKGSSIGLITAGLMSLAFMGFSGLVKF
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rnf electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MLTC_SHIFL
Sequence: MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQNTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: NRAM_I72A0
Sequence: MNPNQKIITIGSVSLGLVILSIILHVVSIIVTVLVLSNTGTGLNCNGTIIKEYNETVRVERITQWYNTNIIEYIGRPSNEYYMNNTESLCEAQGFAPFSKDNGIRIGSRGHVFVIREPFVSCSPLECRTFFLTQGSLLNDKHSNGTVKDRSPYRTLMSVEVGQSPNVYQARFEAVAWSATACHDGKKWMTVGVTGPDAQAVAVVHYGGVPVDVINSWAGDILRTQESSCTCIKGDCYWVMTDGPANRQAQYRIFKAKDGRIIGQNDINFNGGHIEECSCYPNEGKVECVCRDNWTGTNRPILVISPNLSYTVGYLCAGIPTDTPRGEDSQFTGSCTSPLGSQGYGVKGFGFRQGNDVWVGRTISKTSRSGFEILKIKNGWTQNSKDQIQKQVIVDNLNWSGYSGSFTLPVELTKKGCLVPCFWVEMIRGKPEEVTIWTSSSSIVMCGVDNKVANWSWHDGAILPFDIDKM
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: UPPP_THET2
Sequence: MGRVSAWEALLLGVVEGLTEFLPVSSTGHLTLLFHLLGLPVEEDPFLKTFLVAIQLGAILAVLLLYGRRLAADRALWLRIAVAFVPTGVIGFFFYPLIKGVILGNDAVVAFFLFFVGAVLLFADRLAERAQYQDVKALPLARVAWIGVFQGLAALFPGTSRSGATILGGLLLGLNRQAAAEFSFLLALPTMFAAVGYDLWKSAPEVPEGGWSLLLLGFLAALATALVTVRWMLAFVARHGFRPFALYRMALAAVYAFFFLR
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GROA_HUMAN
Sequence: MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN
What is the function of this protein?
Has chemotactic activity for neutrophils.  May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion.  In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
What are the official names of this protein?
Growth-regulated alpha protein, C-X-C motif chemokine 1, GRO-alpha(1-73), Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRX2_HHV2H
Sequence: MITDCFEADIAIPSGISRPDAAALQRCEGRVVFLPTIRRQLALADVAHESFVSGGVSPDTLGLLLAYRRRFPAVITRVLPTRIVACPVDLGLTHAGTVNLRNTSPVDLCNGDPVSLVPPVFEGQATDVRLESLDLTLRFPVPLPTPLAREIVARLVARGIRDLNPDPRTPGELPDLNVLYYNGARLSLVADVQQLASVNTELRSLVLNMVYSITEGTTLILTLIPRLLALSAQDGYVNALLQMQSVTREAAQLIHPEAPMLMQDGERRLPLYEALVAWLAHAGQLGDILALAPAVRVCTFDGAAVVQSGDMAPVIRYP
What is the function of this protein?
Structural component of the T=16 icosahedral capsid.  The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes.  These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2.  Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly.
What are the official names of this protein?
Triplex capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRX2 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: AXE1_EMENI
Sequence: MVKLQYLLSILLYAYSCTALMLDRRDPTPGQLSQVTDFGDNPTNVGFYIYVPQNLASNPAIIVAIHYCTGTAQAYYSGTPYAQYAETYGFIVIYPESPYSGTCWDVSSQSTLTHNGGGNSNSIANMVDWTINQYNADASRVYVTGTSSGAMMTNVMAATYPNLFAAGIAYAGVPAGCFYSEANVEDQWNSTCAQGQSISTPEHWAQIAQAMYSGYEGSRPKMQIYHGSADATLYPQNYYETCKQWAGVFGYNYDSPQEVQNDTPVAGWAKTIWGENLQGILADGVGHNIQIQGEEDLKWFGFTS
What is the function of this protein?
Acetylxylan esterase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone.
What are the official names of this protein?
Acetylxylan esterase A.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate esterase 1 (CE1) family. AxeA subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: A6907_ARTBC
Sequence: MPSFVLWTFHLCSQWFQGLTDLLPHIPDTQTVNNFASQTGLLYPGGMKYSKIASWVCIPLLTCRGVDATNSADGGSELQLNESPFSKNWQVLGPFEIGTRESSWGADPLEAYGGFQTLQYDPKASFDSSLALNGLANWSMASTHVNSTANPPETILDINLSPDNLTSLQEVYGWDAKQYQAWARGTLTVSKSNSVVALYTDRIWEYRIDNKSYFGGDFFGFRRAPLLLDLSPGTHTVDLRVVRDVRALGAVGEPFINVTLIAQELSKTLIVDKKSILVADVVENRLISPHASVTLHNTMGNPVDVAARFSLKMLNNNVKLEEAQSRAIGFTIEAKDKINVPSSVSLYFEYTTPDDSSVQRTQTMTITFTRRKLPEVQQNTFMLPGGVVSYATMRPPTSLECNKDKSAKLPVLLGLHGAGQAASDEIIRTMLDGVSDICAWTLFPSGVTPWSGDDWHTWGFADLQHSVRALNDYIKYSGWTGVGLIDGDWIIAGHSNGGQGTWYTISHYPDKIIAAAPVAGYTSIENYVPYSMWHNTDSLLASTFYRARQDFKHEILVDNFAGIPVYQQHGASDDNVVVYHSRLMHRLLQESGSPSKYHEVPGKNHWYTGIMTSDFLKDFYRTYVQRPNATDLLPQRFSVTLPPAGHMGTRGGIYVDQSHTPDRVGSIEVERGMANDGVWKLKTRNIRRFHLETSAIRSHVPLYIQIDGSRFTVTPSNSTTTWYTQDAAGKWTSGGDSWRTISQRYGRQAGVNAFLRTEAPFTVTAAAQETRDLALQTCRNLFQYLSADCIISYAVPTANSTTATSPAGNNVVILLGAQPNGYTAGDSAISISARSLDIKTSQGTTSYPFEPGLGAIFIRPLVNERLELVIWGSDMAGLQQAARLVPVLTGVGQPDFVVVNKGTPLKGQGSLYAAGFFDSEWKVSAASYVS
What are the official names of this protein?
Uncharacterized secreted protein ARB_06907.
Protein: RS15_PSEA6
Sequence: MSLTTQETAAIIADYGVKEGDTGSPEVQVALLTSNINKLQGHFADHKKDHHSRRGLLRMVSQRRKLLDYLKGKNVERYQDLIKRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: TYSY_SHEB8
Sequence: MKQYLDLMKHILAEGVDKSDRTGTGTRSVFGYQMRFDLSKGFPLVSTKKCHMRSIIHELLWFLKGETNVAYLRENKVSIWDEWADDNGDLGPVYGAQWRSWPTQSGDAIDQISQVIAQIKSQPDSRRLIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLTMMVAQQCDLALGDFVWTGGDTHLYSNHMEQTALQLSREPMPLPTMTILRRPESIFDYQFDDFELTNYAPHPHIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU3_SHIBS
Sequence: MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDITGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVAEGV
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_STRA5
Sequence: MEVKTLANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELYRAASSSIDKAASKGLIHTNKASRDKARLATKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HRH2_RAT
Sequence: MEPNGTVHSCCLDSMALKVTISVVLTTLILITIAGNVVVCLAVSLNRRLRSLTNCFIVSLAATDLLLGLLVLPFSAIYQLSFTWSFGHVFCNIYTSLDVMLCTASILNLFMISLDRYCAVTDPLRYPVLVTPVRVAISLVFIWVISITLSFLSIHLGWNSRNGTRGGNDTFKCKVQVNEVYGLVDGLVTFYLPLLIMCVTYYRIFKIAREQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEAVEGIVLWLGYANSALNPILYAALNRDFRTAYQQLFHCKFASHNSHKTSLRLNNSLLPRSQSREGRWQEEKPLKLQVWSGTELTHPQGNPIR
What is the function of this protein?
The H2 subclass of histamine receptors mediates gastric acid secretion.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Histamine H2 receptor, H2R, HH2R, Gastric receptor I.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FADR_SALNS
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHDSGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G37L1_BOVIN
Sequence: MRWLWPLGVSLAVALAAGPERAPRGVWLQQGGHQPVAQEQPDRSRRGAEREDAKGLQQYVPEGWAEYPRPIRPAALQPTQPWVAASPSPDRARATGGSGQEPQGNVTGPPGQRPQVQNPLYPVTERSYGAYAVLLLALLLFAVGIVGSLAVMCIVWHSYYLKSAWNSVLASLALWDFLVLFFCLPVVTFHEITKQRLLGAVSCRAVPFVEVSSLGVTTFSLCALGIDRFHVATSTLPKARPIEPCPSILAKLAVIWVGSMTLAAPELLLWQLVREPSPAAGTVDTCIMKPSAHLPESLYSLVLTYQNARMWWSFGCYFCLPVLFTVTCQLVTWRVRGTPGRKPESRPGPQEPRGARPSSTVAGLAAVHALCALPENVCNVVAAYLSAALTRQTLELLGLVTQFSTFFKAALTPLLLLCVSRPLGRAFLDCCCCCCGEGCGEGCGGRAAPAGPRAKLHTELSASGYFHKPREAPPLLALGTPC
What is the function of this protein?
G-protein coupled receptor (By similarity).  Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade (By similarity).  However, other studies have shown that prosaposin does not increase activity (By similarity).  It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha (By similarity).  Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway (By similarity).  Regulates baseline blood pressure in females and protects against cardiovascular stress in males (By similarity).  Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity (By similarity).
What are the official names of this protein?
G-protein coupled receptor 37-like 1, Endothelin B receptor-like protein 2, ETBR-LP-2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Note=Associates with the basal membrane of Bergmann glia cell primary cilia.
Protein: RQCH_BACNB
Sequence: MSFDGMFTYGMTHELNEKIMGGRITKVHQPYKHDVIFHIRAKGKNQKLLLSAHPSYSRVHITAQAYENPSEPPMFCMLLRKHIEGGFIEKIEQAGLDRIMIFHIKSRNEIGDETVRKLYVEIMGRHSNIILTDAAENVIIDGLKHLSPSMNSYRTVLPGQDYKLPPAQDKISPLEASEDDILRHLSFQEGKLDKQIVDHFSGVSPLFAKEAVHRAGLANKVTLPKALLALFAEVKEHRFIPNITTVNGKEYFYLLELTHLKGEARSFESLSELLDRFYFGKAERDRVKQQAQDLERFVVNERKKNANKIKKLEKTLEYSENAKEFQLYGELLTANLYMLKKGDKQAEVINYYDEESPTITIPLNPNKTPSENAQAYFTKYQKAKNSVAVVEEQIRLAQEEIEYFDQLIQQLSSASPRDISEIREELVEGKYLRPKQQKGQKKQKPHNPVLETYESTSGLTILVGKNNRQNEYLTTRVAARDDIWLHTKDIPGSHVVIRSSEPDEQTIMEAATIAAYFSKAKDSSSVPVDYTKIRHVKKPNGAKPGFVTYDSQHTVFVTPDADTVIKLKKS
What is the function of this protein?
Plays a role in bacterial binding to eukaryotic host fibronectin and other extracellular matrix proteins (Probable).  Wild-type cells inhibit binding of S. aureus, L. monocytogenes and E. faecalis to human fibronectin in vitro, bacteria with a deletion of this gene no longer do so (PubMed:28294433).
What are the official names of this protein?
Rqc2 homolog RqcH, RqcH, Fibronectin-binding protein YloA.
What is the protein family that this protein belongs to?
Belongs to the NEMF family.
Protein: CMT3_ORYSJ
Sequence: MAPSSPSSAAAPTRTSTRKRAASASASAKATDEPSTKRTRRPKAETKPRKKKDEVKEEEKPPMEDDACGEEPDAEEMALGEEAEAEEAEAEQKQLDAPAPGVARKRVAQPSRVRHGSDGDHDPEFVGDPFPAKEARDKWPQRYQRNAATRRPDEEEDIKARCHYSSAKVDGTLYCLHDDVYVKAEEDKADYIGRITEFFEGTDHCHYFTCRWFFRAEDTVISSIMMENADDEKHDLKRVFLSEEKNDNVLDCIISKVKIVYIDPNMESEAKARRLADCDLYYDMSYTVAYSTFANIPLENGASGSDTASDISSDDVDSSKGKVVSDSEASSVGKATLLDLYSGCGGMSTGLCLGAALAGLNLETRWAVDFNSFACESLKYNHPRTEVRNEKADEFLALLKGWHSLCDEYVKKDIDFSSAGASENEEDDDEPLEKDEFVVEKLAGICYGGSGREDGLYFKVQWKGYGREEDTWEPIENLRDCPLKIKEFVQEGYRRKILPLPGDVDVICGGPPCQGISGFNRFRNRKEPLKDEKNKQMVTFMDIVAYLKPKYVLMENVVDILKFADGYLGRYALSRLVAMKYQARLGMMVAGCYGLPQFRMRVFLWGALPTMVLPKYPLPTHNVVVRGGAPNAFSQSIVAYDETQKPTLKNALLLGDAISDLPEVNNHQPNEVMEYGSSPKTEFQRYIRLSRKEMLDSSFEGKDGPDLGKLLDHQPLKLNKDDHERVQQIPVKKGANFRDLKGVRVGANNIVEWDPDVPRVYLSSGKPLVPDYAMSFIKGRSLKPFGRLWWDETVPTVVTRAEPHNQIILHPNQARVLTVRENARLQGFPDYYKMFGPIKEKYIQVGNAVAVPVARALGYSLGLAYQRESEGSSPLFVLPDSFTEVGRQAAPARASSVGIPVGEVVEQ
What is the function of this protein?
Involved in CpXpG DNA methylation.  Plays a critical role in the maintenance of CpXpG DNA methylation and suppression of a wide spectrum of transposable element (TE) activities.  Required for proper plant development in reproductive stage.
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase CMT3, Chromomethylase 3, OsCMT3a.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.