PharMolix/UniProtQA huggingface dataset:
Protein: PCKG_BORBR
Sequence: MNKPSEVKPVALNVPDYVKHSGLIAWVERIAALTKPDRVVWCDGSQEEYDRLCEQMVQGGTMRRLNPAKRANSYLACSDPSDVARVEDRTFICSEREEDAGPTNNWAAPQAMRETLGGLFDGAMRGRTMYVVPFSMGPLGSPIAHIGVELSDSPYVVVNMRIMTRMGRKVFDVLGSDGAFVPCVHSVGMPLAEGQQDVAWPCNPTKYIVHYPETREIWSFGSGYGGNALLGKKCFALRIASTMGRDEGWLAEHMLILGVTSPKGRKYHVAAAFPSACGKTNFAMLIPPHGMDGWKVTTIGDDIAWIKPGPDGRLHAINPEAGYFGVAPGTSEKTNFNAMATLKANVIFTNVALTDDGDVWWEGMTDTPPAHLIDWQGQDWTPAIAAETGRKAAHPNARFTAPAAQCPSIDPEWENPKGVAIDAFIFGGRRSTTVPLVTEARNWVEGVYMAATMGSETTAAAAGQQGVVRRDPFAMLPFCGYNMSDYFDHWLKLGRRLEETGATLPRIYCVNWFRKGPDGKFVWPGFGENMRVLRWMLGRLDGQAGGVDQVFGISPAYGDIDWTGLEFSPDKFEQVISVDLPAWRAELALHDELFTQLAARLPEDLPLTRTAIERRMAA
What is the function of this protein?
Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase [GTP], PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABP2_ECHGR
Sequence: MEPFIGTWKMEKSEGFDKIMERLGVDYFTRKMGNMMKPNLIISDLGDGRYNMRSESKFKTSEFSFKLGEQFKEVTPDSREVMSMLTVEDGVLKQEQVGKDKTTYIDRVVYGNELRATVKADELVCVRTYSRGM
What is the function of this protein?
May play a role in the acquisition, storage, and transport of lipids, and may be important to the organism since it is incapable of synthesizing most of its lipids de novo.
What are the official names of this protein?
Fatty acid-binding protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: PIME_MYCS2
Sequence: MRVNGYRGAKVGAVDTTSPPEVPASARLQRLAPMLLVVSILARLAWTYLVPNGANFVDLHVYVGGADALDGPGALYDYVYADQTPDFPLPFTYPPFAAIVFYPLHLLPFGVVAFIWQIGIIAALYGVVRVSQRLMGLQSQRRVAMLWTALGIWTEPLRSTFDYGQVNVVLVLAVLCAVSTTRWWLSGLLVGLAAGIKLTPAVAGLYFLGARRWAAVACSAAVFFATVGVSWLVVGAQARRYFTELLGDADRIGPIGTSFNQSWRGGISRILGHDAGFGPLVLIGIGITAVLALLAWRAIGGAQDRLGGILVVSLFGLVLSPISWTHHWVWLIPLMMWLLHGPLSALRGARILGWGWLALTLLGVPWLLSFAQPTIWEIGRPWYLAWAGLVYIVATLATLGWIAFSRKGSG
What is the function of this protein?
Catalyzes the alpha-1,2 addition of a mannose residue from polyprenol-phosphate-mannose (PPM) to a monoacyl phosphatidylinositol tetramannoside (AcPIM4) to generate a monoacyl phosphatidylinositol pentamannoside (AcPIM5).
What are the official names of this protein?
Polyprenol-phosphate-mannose-dependent alpha-(1-2)-phosphatidylinositol pentamannoside mannosyltransferase, Alpha-mannosyltransferase, Alpha-ManT, PPM-dependent mannosyltransferase, Polyprenol-phosphate-mannose alpha-mannosyltransferase, PPM alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 87 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SODM_ECO57
Sequence: MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALESLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAAIERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGASGFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], MnSOD.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: METE_ECO24
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHNVKPVLLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: RBFA_STAAE
Sequence: MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDLSQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGNKIERMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLH31_MOUSE
Sequence: MAPKKKTIKKNKAEINEMTIIVEDSPLSKLNALNGLLEGSNSLSCVSSELTDTSYGPNLLEGLSKMRQESFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTKRVDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREISVENCMYVVNIAETYSLKNAKATAQKFIRDNFIEFAESEQFMKLTFEQINELLVDDDLQLPSELVAFQIAMKWLEFDQKRVKHAADLLSNIRFGTISAQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLITVGGRPGLTEKSLSRDILYRDPENGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLGSMNQKRTHFSLSVFNGLLYAVGGRNSEGSLASLECYVPSTNQWQPKAPLEVARCCHASAVADGRVIVTGGYIGSAYSRSVCAYDPALDAWQELPQLSTPRGWHCAVALGDRLYVMGGSQLGPRGERVDVLTVESFSPAARQWSFVAPLPVGVSTAGVSALHGRAYLLGGWNEGDKKYKKCIQCFNPELNEWTEDDELPEATVGVSCCTLAMPNSVSRESRASSVSSVPVSI
What is the function of this protein?
Transcriptional repressor in MAPK/JNK signaling pathway to regulate cellular functions.  Overexpression inhibits the transcriptional activities of both the TPA-response element (TRE) and serum response element (SRE) (By similarity).
What are the official names of this protein?
Kelch-like protein 31, Kelch repeat and BTB domain-containing protein 1, Kelch-like protein KLHL.
Protein: RUVA_XYLFT
Sequence: MIGRLRGVLTSKTPPWLVVDVCGVGYELEVPMSTFCELPDVGYEVNLFTHYTQKDDSAALYGFLSESERRLFRHLQRVSGIGTKIALAILSSVSVDTFAGLIQAGDANALTVIPGVGKKTAERMLVELRDRAADFNNGISTSGKLNLDTVSEAALALQQLGYKPAEAARMARDAGTESDDVAIVIKKALQTVLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TRMA_PSET1
Sequence: MAVIKIDTSQYDAQLSEKEQRIAAQFQRFGVDKLEVFSSEPINYRQRAEFRVWHDGDDLFHIMFDQQTKDKIRVDSFDPAAPLVGEVMQVMIDNLKSCEILRRKLFQIDYLSTLSGEILVSLLYHKPLDEHWLSEINTLKEKLSSKYKIDFIGRARKQKEMLGDDYVTERLNVNGQELIYQQVENSFTQPNAKVNIKMLEWAQDLCKPLKNDLLELYCGNGNFSIALAGSFNKVLATEISKSSVHSAQYNIAQNKVDNLDIIRMSSEEFTQAMNGERSFSRLEGIDLNSYNCQTILVDPPRAGMDTLTCDLVANYESIIYISCNPETLERDLDHLTRTHEVKRFAIFDQFPYTHHIESGVFLQKKNT
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: RP3A_HUMAN
Sequence: MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
What is the function of this protein?
Plays an essential role in docking and fusion steps of regulated exocytosis (By similarity).  At the presynaptic level, RPH3A is recruited by RAB3A to the synaptic vesicle membrane in a GTP-dependent manner where it modulates synaptic vesicle trafficking and calcium-triggered neurotransmitter release (By similarity).  In the post-synaptic compartment, forms a ternary complex with GRIN2A and DLG4 and regulates NMDA receptor stability.  Also plays a role in the exocytosis of arginine vasopressin hormone (By similarity).
What are the official names of this protein?
Rabphilin-3A, Exophilin-1.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Cell projection, dendritic spine. Postsynaptic cell membrane. Membrane; Peripheral membrane protein.
Protein: CECA_ANOGA
Sequence: MNFSKIFIFVVLAVLLLCSQTEAGRLKKLGKKIEGAGKRVFKAAEKALPVVAGVKALG
What is the function of this protein?
Antibacterial activity against several Gram-positive and Gram-negative bacteria.  Antifungal activity against A. fumigatus, B. cinerea, F. culmorum, F. oxysporum, N. crassa, C. albicans, C. neoformans and S. cerevisiae.
What are the official names of this protein?
Cecropin-A.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MURB_MYCUA
Sequence: MKRRDVGSLFAGARVAESVPLAPLTTLRVGPVARTLVTCDTTDQVVGVLRELDDRARNGDCGPVLVFAGGSNVVIGDALADLTVVRVANDRVTVDGNLVRAEAGTVWDEVVVATIERGLGGLECLSGIPGSAGATPVQNVGAYGVEVSDVITRVRLLDRSTGDVSWVPAADLSFGYRTSVLKQAEGLALPAVVLEVEFALDASGRSAPLRYGELTAALGMNSGERGEPRAVRDAVLALRTRKGMVLDAADHDTWSVGSFFTNPVVAPEIYERLAAQTGESVPHYPAPDGVKLAAGWLLERAGFGKGYPGDPHARCRLSSKHALALTNRGGATAADVMVLARTVRDGVRDVFGITLKPEPVLVGCAL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_BORHD
Sequence: MQFEVKDLINKIKKDGLEEAEKLASEIILNAKRDAEAIILKAESDAKELKMQAEKEAGEYKIHSLEASRQAVRDLIIATENNIKSLFKIALKDSVSEVYDDNFLRELIIRVVDIWSKKDKIDIILNESAVSNLLSILRVNIGNRLDDAIELKPFKGISKGFKIQQRDGNLYYDFTSDTIADILFEYLNPRFKEVIKLG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: CBP4_EMENI
Sequence: MSRAGTWLKMLGVGIVICVGGPALVEKLRPTDAELIQRYNPELRERSMREGDRRAQEFDDYVTKLKEWSKSDKSIWFAAKEMEEKRLAEQQAIQNQTKEQARIQREEMRKELMGEK
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor cbp4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RUVB_CLOB8
Sequence: MERIVNQSEMQEDFNSELSLRPQKINEYIGQDKVKERLDIFIKAAKNRKEALDHTLLYGPPGLGKTTLANIIAKEMGGDLKITSGPAIERAGELAAILTTLKDYDVLFIDEIHRLNRNVEEILYPAMEDYALDIVIGKGATAKSIRIDLPKFTLIGATTRIGMLTSPLRDRFGVLCAMEYYTDEELKEIVSRSALVFGCAITEEGALEIAKRSRGTPRIANRLLKRVRDYSEVKSNKLVSLKEAREALELLEVDNQGFDKVDNKILEAIIDNFNGGPVGIETLSYFIGEELGTIEDVYEPYLLQKGFIIRTPRGRIASDKAYEHLGRVNNSKSKSNNGKVQGSFFDK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: TX816_LYCSI
Sequence: MKLIIFTGLVLFAIVSLIEVQADNERACLPQYQVCTDAPGNCCSNLVCNCYGRYKSGARIGRNCFCLQKGVIYKREN
What are the official names of this protein?
U8-lycotoxin-Ls1g, Toxin-like structure LSTX-H16.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYFB_BACAN
Sequence: MFVSYRWLQEYVDIKDVTAQELADKITKSGIEVEGVEVLNKGVKGVVVGHVLECEKHPEADKLSKCLIDIGEEEPVQIICGAANIAKGLKVPVAKVGAVLPGNFKIKKAKLRGEASHGMVCALQELGIDGKLVSKEYADGIFIFPSDAEVGADALEILNLHDEVLELGLTPNRADCLNMLGVAYEVAAIYGREVKLPAIDLQETAEKTSDYISVSVEAKEENPLYIAKMVKNVKIGPSPMWMQTRLMAAGIRPISNVVDITNYILMEYGQPLHAFDYDKLGSKEIVVRLAKEGEKIETLDDQERTLQSHHLVITNGTKALAVAGVMGGADSEVTNETVNVLIESAYFAGQTVRRTSKDLGLRSESSARFEKGIDPTRTFEAIQHAAALMAKYAGGEALEGVVEADNLQVQERTVSVTAEKVNRVLGTNISASEMGTMFTNLKFPFTEVEGTFHVNVPARRPDITISEDLVEEVGRLYGYDHIPVTLPSGTMTRGKLTAAQTKRRKVRRFLEGAGLYEAITYSLTSADKAKQYMVEPNEKAPVNLALPMSEERSQLRLSLVPQLLEAVSYNVARKNDSVALYEVGSIFLPTEAGELPKEEQHLAGVMTGLALHHAWQGEKKVVDFFVVKGVLEGLFDVLGVSNQITYAPAKREGMHPGRTADIVLDGEVIGFIGQLHPEAEKQLDVKNTFVFELSLVKVFGTDAEETYYSAIPRFPSMTRDMAVVVTKETKAGEMKQVIAEAGGELLKDVTLFDLYEGEKMEEGKKSLAFSMNYFDPERTLTDEEVTEAHNRVLTAVEEKFGAELRK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_STRA1
Sequence: MEVAEIRQKIVENKEKLTSFRRSLDLDRLEEEIALLENQMTEPDFWNDNIAAQKTSQELNELKGKYDTFHNMQELSDETELLLEMLDEDDSLKEELEENLMQLDKIMGAYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDLLLRMYTRFGNANGFKVEVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFASVEVMPELDDTIEVEVRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVSSTVDRTQYGNRDRAMKMLQAKLYQLEQEKKAQEVDALKGDKKEITWGSQIRSYVFTPYTMVKDHRTNFELAQVDKVMDGEINGFIDAYLKWRIED
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_RHILW
Sequence: MTMTDPLGDMLTRIRNGASRRKSSVSTPASKLRARVLDVLQSEGYIRGYSVVDFGNGKSELSIELKYYEGASVIREIGRVSKPGRRVYVSVKSIPQVANGLGITILSTPKGVMADHQAREQNVGGEVLCSVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: TATD_PECPW
Sequence: MFDIGVNLTSSQFEQDREQVVIRAKQAGVSGILITGTNAQESHQAMLLAQAYPDYCWSTAGVHPHDASQWNGDIAEQVHHMANAACVVAIGECGLDFNRNFSTPEEQERAFSAQLAIAAELSMPVFLHCRDAHPRFISLLTPWLGQLPAAVVHCFTGNRQELDACLAVGLTIGITGWVCDERRGLELRALLPHIPADRLLVETDAPYLLPRDLRPKPASRRNEPCYLPHIIRQIAEWRGEDATWLGQITDENARRIFRLA
What is the function of this protein?
3'-5' exonuclease that prefers single-stranded DNA and RNA.  May play a role in the H(2)O(2)-induced DNA damage repair.
What are the official names of this protein?
3'-5' ssDNA/RNA exonuclease TatD, DNase TatD.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. TatD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFUB_HORCR
Sequence: MVHLASIVSDLGFWPTVAGTVATYLFYQIVATVYDVYFGPMSNIPGPKLWAASHIPYILMLWNGEDASTKLALHEKYGPVVRVSPTELSYREAQAWKDIYGHQTRGKKSFPKDSRFYAPAVNGAPSILNADDPTHTRHRRILAHAFSDKALKEQEPLLKKWSDMLVSKLKENVEKSPSTPLDLVSWFNFTTFDIMADLTFAEPLYMLEGSTYSPWVRTIFGSLKLGSRLRAVRILPGMTTFINMIMPNSMRQKQVEHFKYSADRVDKRLANKNLDRPDLWAQVLKRVDVDGMSMSVAEMHSNSAIFMLAGTETTATLLSGLTYHLLQNPATMSKLVNEVRSTFPTRDDINVETLQRLPYLNACLEEGMRMYPPVATGLPRLTPKGGAAICGTWIPEDVAVSVSQWSTYQCEENFHKAKLFIPERWMGEDEQFANDNHAAFQPFSTGPRNCIGRNLAYHEARLLLCEVLWNFDLTLDEKSEDWLNQPVFTVWEKDPLWVRLQVASR
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of enfumafungin, a glycosylated fernene-type triterpenoid with potent antifungal activity, mediated by its interaction with beta-1,3-glucan synthase and the fungal cell wall (PubMed:30051576).  The pathway begins with the terpene cyclase-glycosyl transferase fusion protein that most likely uses 2,3-oxidosqualene as substrate and catalyzes glycosylation immediately after cyclization (Probable).  The fernene glycoside then could be processed by the desaturase efuI which catalyzes isomerization of a double bond established by efuA to form the core structure (Probable).  The latter would then undergo a series of hydroxylations in unknown order at C-2, C-19, C-23 and C-25, which would be catalyzed by two of the three cytochrome P450 monooxygenases efuB, efuG or efuH (Probable).  The hydroxy-group at C-25 becomes oxidized by the dehydrogenase efuE to enable a spontaneous, non-enzymatic hemiacetal formation with C-23 (Probable).  After hydroxylation at C-2, acetylation by the acetyltransferase efuC takes place (Probable).  The final steps in enfumafungin biosynthesis require expansion of the 5-membered ring by lactonization via a Baeyer-Villiger reaction mediated by one of the BGC's cytochrome P450 monooxygenases (efuB, efuG or efuH) followed by ring cleavage (Probable).  This type of reaction would establish a double bond between C-20 and C-21 which could be reduced by the reductase efuL to form the final product (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase efuB, Enfumafungin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CWBA_BACSU
Sequence: MKSCKQLIVCSLAAILLLIPSVSFAADSNISVKLLNYIGNKSSISLSPTGFYKVTGDNVAVTDRFAGASRYETATLASNSQWKNPNTVILVNRDIFIDALPVIPLAKKLNAPVLFTQPDTLTKTTERQIAKFNPDNILIIGGARSISKDVENKLKSYGAVKRISGKNRYVLSENIAKQMGSYDKAIVVTGRVFQDALAIAPYAAAHGYPILLTEKDKLPDYDLPKQVIIIGSSFSVSDSVENQIKKTSTVQRIPGSTRYELTANIIKQLKLKADKVVMTNGTKYADVLIGASLASKKNSQILFVKQDSVPAAAKSITKDKATYAYDFIGSTSSISAEVENSLADEFYLADGGTYNLKINSGKLNLENIKTYGNSLRIKPENYSTSNRISLDGKQYLGTVNFSIESTKYIRPVNENIPFEDYLKGVIPNEMPASWSLEALKAQTVAARTYSITKTGTTVPDTTAFQVYGGYSWNSNTNKAVEQTKGKVLKYNGSLITAAYSSSNGGYTEASNEVWSSSVPYLIAKKDTKDPQIGWTLTLSKQQLDTKSLDLTKPSSWWSSATETDSARLSGVKNWILKNKETSADSVKIASIDDLSFSGTTQGQRAKTASMKVKYFVKSSTGSYNLSKITTISVPTSELRTMIGATVFKSTYVTVKKDTSKYTISGKGYGHGIGMSQYGAKARAEAGDSYSSILKFYYPGTTLTSY
What is the function of this protein?
Possibly involved in cell wall metabolism during spore formation.  Enhances the amidase activity approximately threefold.
What are the official names of this protein?
Amidase enhancer, Cell wall-associated polypeptide CWBP76, CWBP76, Modifier protein of major autolysin.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Secreted, cell wall. Note=Cell wall localization shown in PubMed:11987133.
Protein: T41AA_DANRE
Sequence: MRSLVGLVAVIVTATFYLYSLSVFLPPGPQLHKQSHEGETTDAKDGDEPSEMETASSRLKFPSDLDELKEMAELLQFYKTEHTGYVLLLFCSAYLYKQAFAIPGSSFLNILAGALFGTWFGLLLTCVLTTVGATLCFLLSQAFGKHHIVKLFPDKVAMLQKKVEENRSSLFFFLLFLRFFPMSPNWFLNMTSPILNIPVTLFFMAVFIGLMPYNFICVQTGSMLSQISSLDDLFSWSVVLKLLLTACVALLPGALIRKYSTRHLHLDGLETNGLSQNKKNR
What are the official names of this protein?
Transmembrane protein 41A-A.
What is the protein family that this protein belongs to?
Belongs to the TMEM41 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DDGS_NOSP7
Sequence: MSNVQASFEATEAEFRVEGYEKIEFSLVYVNGAFDISNREIADSYEKFGRCLTVIDANVNRLYGKQIKSYFRHYGIDLTVVPIVITEPTKTLATFEKIVDAFSDFGLIRKEPVLVVGGGLTTDVAGFACAAYRRKSNYIRVPTTLIGLIDAGVAIKVAVNHRKLKNRLGAYHAPLKVILDFSFLQTLPTAQVRNGMAELVKIAVVANSEVFELLYEYGEELLSTHFGYVNGTKELKAIAHKLNYEAIKTMLELETPNLHELDLDRVIAYGHTWSPTLELAPMIPLFHGHAVNIDMALSATIAARRGYITSGERDRILSLMSRIGLSIDHPLLDGDLLWYATQSISLTRDGKQRAAMPKPIGECFFVNDFTREELDAALAEHKRLCATYPRGGDGIDAYIETQEESKLLGV
What is the function of this protein?
Catalyzes the conversion of sedoheptulose 7-phosphate to demethyl-4-deoxygadusol (DDG) (PubMed:20813918, PubMed:22741921).  Involved in the synthesis of the mycosporine-like amino acid shinorine, a natural sunscreen compound that protects the cell against UV radiation (PubMed:20813918).
What are the official names of this protein?
Demethyl-4-deoxygadusol synthase, DDGS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. DDGS family.
Protein: PETN_CHLSC
Sequence: MDTVSLAWAALMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.