PharMolix/UniProtQA huggingface dataset:
Protein: PP4R2_ASHGO
Sequence: MQSGEESRLGIKCASLHEELTQIVIDQDVGPLQRVPASEFLARLVEHMGQTIPREVFGAEAETGTRDLERLGAIVAYIDENFAAQNVLPFTIQRICELCYHPLHYFRVGELRKFVNALEKVCYVRSSWSAGYGAVPSPAEGTPTREASVDVSMSKIPWLPDDGGRDLRQFIEKIESIVSVNFGYEDDEDEGRDAAIQEYYDNEGAGDDEDDDQDYVDEDSATSEDEEEDVEEEEEEEGPEPEVGLEPVHAESAPEECVGTNKRTTAEREDCHMQPCAAAHSTDGAHPCGLKRSKLQEDGATMASPPDIVAEGGSHDPQVVDASKPPQLTTSATNVSCNASIEATVSLDDDSTAGGE
What is the function of this protein?
Regulatory subunit of the histone H2A phosphatase complex, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process.  Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 2, PP4R2.
What is the protein family that this protein belongs to?
Belongs to the PPP4R2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADK_AGARV
Sequence: MKHFVVIANAYKDRDFALTNKIVAYIEQKGGTAKGLMSNVEAISDNEFELEDIPQDTQCILVLGGDGTLIRAATRVETLEIPLMGVNLGTLGYLCEVEEATVFDAIDSLMADKYMTEDRIMLIGHKRGSETSRVALNDIVIHRKGNLQILSLNVYVNGEFLNNYHADGIIVATPTGSTGYSMSAGGPIVDPKGDMILLTPNNAHNLTSKSIVLSGDDEIEIEILSRREQNDELACVSYDGDTTAELAVGDRFVISRAANHTKICKLHQRSFLEILRKKMGNYS
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_CAMJE
Sequence: MKNLILAIESSCDDSSIAIIDKNTLECKFHKKISQELDHSIYGGVVPELAARLHSEALPKMLKQCKEHFKNLCAIAVTNEPGLSVSLLSGISMAKTLASALNLPLIPINHLKGHIYSLFLEEKISLDMGILLVSGGHTMVLYLKDDASLELLASTNDDSFGESFDKVAKMMNLGYPGGVIIENLAKNAKLKNISFNTPLKHSKELAFSFSGLKNAVRLEILKHENLNEDTKAEIAYAFENTACDHIMDKLEKIFNLYKFKNFGVVGGASANLNLRSRLQNLCQKYNANLKLAPLKFCSDNALMIARAAVDAYEKKEFVSVEEDILSPKNKNFSRI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_BURL3
Sequence: MNRIQQTFAALAEQGRKGLIPFITAGDPDPAKTVEFMHALAEGGADVIELGVPFSDPMADGPVIQRSSERALARGVTLKSVLADVKRFRETDPKTPVVLMGYANPIERMGVDTFAAEAQAAGVDGVLVVDYPPEEAGVFAEKMRAAQIDPIFLLAPTSTDERIADVGKIASGYVYYVSLKGVTGAGNLDVSSIAGKIPAIKSRVPVPVGVGFGIRDAETARAVAEVSDAVVIGSRLVQLLESAAPEGAAAALKTFIAELRAALDGAGKTAR
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NDPA_PHOPR
Sequence: MSLTLSNVILHQLTKNDQDEIEINLRNQVLDADSSTEGLVAELHRVYSSKGAKGFALFAEDSEFCHWLKQYRTGEMDFVTFSNQSAQRLQVELAKYPFAEAGTLVMAEYQSLATDYLFIGLLPTCHSMKVTEQLDISATDYLDVAKMDIVARIDLSSWETNSDSNRYLTFIKGRVGRKISDFFLDFLQAVVGLDAKEQNQVLMQAVEDFCADSRLDKEEKQQYRKQVYDYCNGQLQAGDEVAVKELAGELPPAEDGTNFYEFTSKQGYELEESFPADRTAMRKLTKFVGAGGGMSINFDSMLLGERIFYDAETDTLTIKGTPPNLKDQLLRRLNTDN
What are the official names of this protein?
Nucleoid-associated protein PBPRA2585.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LUXD_VIBHA
Sequence: MNNQCKTIAHVLRVNNGQELHVWETPPKENVPFKNNTILIASGFARRMDHFAGLAEYLSENGFHVFRYDSLHHVGLSSGSIDEFTMTTGKNSLCTVYHWLQTKGTQNIGLIAASLSARVAYEVISDLELSFLITAVGVVNLRDTLEKALGFDYLSLPIDELPNDLDFEGHKLGSEVFVRDCFEHHWDTLDSTLDKVANTSVPLIAFTANNDDWVKQEEVYDMLAHIRTGHCKLYSLLGSSHDLGENLVVLRNFYQSVTKAAIAMDGGSLEIDVDFIEPDFEQLTIATVNERRLKAEIESRTPEMA
What is the function of this protein?
Acyl transferase is part of the fatty acid reductase system required for aldehyde biosynthesis; it produces fatty acids for the luminescent reaction.
What are the official names of this protein?
Acyl transferase, ACT, C14ACP-TE, Myristoyl-ACP-specific thioesterase.
What is the protein family that this protein belongs to?
Belongs to the LuxD family.
Protein: BINA2_LYSSH
Sequence: MRNLDFIDSFIPTEGKYIRVMDFYNSEYPFCIHAPSAPNGDIMTEICSRENNQYFIFFPTDDGRVIIANRHNGSVFTGEATSVVSDIYTGSPLQFFREFKRTMSTYYLAIQNPESATDVRALEPNSHELPSRLYFTNNIENNSNILISNKEQIYLTLPSLPENEQYPKTPVLSGIDDIGPNQSEKSIIGSTLIPCIMVSDFISLGERMKTTPYYYVKHTQYWQSMWSALFPPGSKETKTEKSGITDTSQISMTDGINVSIGADFGLKFGNKTFGIKGGFTYDTKTQITNTSQLLIETTYTREYTNTENFPVRYTGYVLASEFTLHRSDGTQVNTIPWVALNDNYTTIARYPHFASEPLLGNTKIITDDQN
What is the function of this protein?
Component of a binary toxin active against Culex and some Aedes mosquito larvae (PubMed:1512580, PubMed:8419297).  The individual subunits are not toxic.  BinAB binds to the gastric caecum and posterior midgut of C. quinquefasciatus larvae; this subunit alone binds the entire larval gut.  Binary toxin internalization into host gut cells requires both proteins (PubMed:1512580).  Toxic to Aedes atropalpus mosquito larvae; mortality towards both C. quinquefasciatus and A. atropalpus is maximal by 48 hours.  A. aegypti is not very susceptible to this toxin (PubMed:8419297).
What are the official names of this protein?
Binary larvicide subunit BinA, 41.9 kDa insecticidal toxin, Larvicidal toxin protein P42.
What is the protein family that this protein belongs to?
Belongs to the toxin_10 family.
What are the subcellular locations of this protein?
Spore, perispore.
Protein: ARGI_STAAN
Sequence: MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
What are the official names of this protein?
Arginase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: RNH2_ACIET
Sequence: MRSRTSLLEQAALDWHPPGLVAGVDEAGRGPLAGPVVAAAVILDDLQPIAGLADSKVLTAARREKLYDEIRAKALCCSIAEASVEEIDQHNILQATMLAMRRAVLGLRLKPVRVLVDGNRLPPLDVPAEAIVKGDALVASISAASILAKVTRDRWCAQLHQQYPVYGFAGHKGYGTAEHLAALEVHGACPQHRRSFAPVARALQAPVAA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB28_MOUSE
Sequence: MSDSEEESQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKADKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEPLSRTVNPPRSSMCAVQ
What are the official names of this protein?
Ras-related protein Rab-28.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium basal body. Note=Expressed in the basal body and ciliary rootlet of the photoreceptors.
Protein: PEX21_CANGA
Sequence: MSQYCAADPIQRMVSRKGPYLDTQQQRVYKHRSGTGHGTNIRQPTTGIVEATFLQNNSGMNAVHPTTLNVQTHNAHATGRTIAKSVDTNSWVNDFSSMKVQDPLEFADSYKNLYKQYEQKQFHNTVPAQCPRNLYIPTVTRPQTTLNIVDHHEDKSSAVDQLIDDEFEKIEEEVKDQNQKLEFQESAQSFIEICERSQMKEKLQRSKFFQVMQKVSDGEATIRQDGENYVIR
What is the function of this protein?
Mediates peroxisomal import of proteins containing a C-terminal PTS2-type peroxisomal targeting signal via its interaction with PEX7 (By similarity).  Interaction with PEX7 only takes place when PEX7 is associated with cargo proteins containing a PTS2 peroxisomal targeting signal (By similarity).  PEX7 along with PTS2-containing cargo proteins are then translocated through the PEX13-PEX14 docking complex together with PEX21 (By similarity).
What are the official names of this protein?
Peroxisomal protein PEX21, Peroxin-21.
What is the protein family that this protein belongs to?
Belongs to the peroxin-21 family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYB_BALPH
Sequence: MTNIRKTHPLMKIVNDAFVDLPTPSNISSWWNFGSLLGLCLIMQILTGLFLAMHYTPDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLYAHMGRGLYYGSYAFRETWNIGVILLFTVMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAIVHLIFLHETGSNNPTGIPSDMDKIPFHPYHTIKDILGALLLILILLMLTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILAFIPMLHTSNQRSMMFRPFSQFLFWVLVADLLTLTWIGGQPVEHPYMIVGQLASILYFLLILVLMPVTSLIENKLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YEYA_SCHPO
Sequence: MTELHPDEQHVFLQCLNKMQKELDLSFERYERLFKTTQELQEKVKFSSSRFYNKDSTYSKDQGLAKESAALELQKLKQENVLLRKDLNNLEQISDCYAKGMDDIMKHVATYTATMNERMNACHKEYIKMYEALASERNSLYKINEQNVQSLNKVKEWLLKSLEEEP
What are the official names of this protein?
Uncharacterized protein C2C4.10c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ARPC3_HUMAN
Sequence: MPAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEIKNEADRTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKPANKQEDEVMRAYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLSGPGQ
What is the function of this protein?
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947).  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 3, Arp2/3 complex 21 kDa subunit, p21-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC3 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection. Nucleus.
Protein: TPIS_WOLPM
Sequence: MSFLIVANWKMNGMRSSFVDFIGKLNNKSNEITSKLVICPPFTSFPSSIELNNNIDIGAQNCHHKKFGSYTGEISAEMLKELGCTYVMLGHSERANEKDSEIKLKSEIAIESGLHPIICVGENSEDYKNEKTKEVIEYQCKNRLPTHGEYTVAYEPIWAIGTGHVPNNDAIAKVIEVIKLCTSKKHIIYGGSVSSENIENLLSISNLSGVLIGSASLDFDHFYKIIQQVEKKFSLINSKISN
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_SHISS
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLTRAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLEIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAAVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: Y2155_DESRM
Sequence: MIITTTGIIEGKPIRQYFGLVNGEAIMGANVVRDIFASITDIVGGRSGAYESKLAHAREIALEEMTEQARRMGANAIVGVDLDYEVIREGMLMVSASGTAVQI
What are the official names of this protein?
UPF0145 protein Dred_2155.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: VATA1_EQUAR
Sequence: AEVLMDFPQLTMTLPDGREESVMKLTTLVA
What is the function of this protein?
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase.  V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
What are the official names of this protein?
V-type proton ATPase catalytic subunit A isoform 1, V-ATPase subunit A 1, Vacuolar proton pump subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: EX7S_SALSV
Sequence: MPKKNEAPASFETALSELEHIVTRLESGDLPLEDALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEEASPEPFIADNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDSB_RAT
Sequence: MAVSAFQLWRAGGLLRRNFLTHSSSWKIPPRVLKSSQPEALLSVTNNALCFAPLQTFTDEDIMMQKAVKKFAQEQIAPLVSTMDENSKMEKSVIQGLFQQGMMGIEVEAKYGGTEASFLCSVLVIEELAKVDASVALLCDIQNTVINKLFRKHGTEEQKATYLPKLVTEKLGSFCLSEAGAGSDSFALKTRADKSGNYYVINGSKMWISNAEHAELFLVFANVDPPSGYRGITCFLVDRDTEGFQIGRRENKMGIRASSTCQLTFENVKVPETSVLGKIGHGYKYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERMQFGKRIFDFQGLQHQVAHVATQLEAARLLTYNAARLVEAGRPFIKEASMAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKIGTIYEGTSNIQLNTIAKHIDAEY
What is the function of this protein?
Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (PubMed:8660691, PubMed:6874697, PubMed:12855692).  Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA (PubMed:8660691, PubMed:6874697, PubMed:12855692).  Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway (By similarity).  Can also act on valproyl-CoA, a metabolite of the valproic acid drug (PubMed:8660691).
What are the official names of this protein?
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial, SBCAD, 2-methyl branched chain acyl-CoA dehydrogenase, 2-MEBCAD, 2-methylbutyryl-coenzyme A dehydrogenase, 2-methylbutyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RS20_STRZJ
Sequence: MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELFRAASSAIDKAETKGLIHKNKASRDKARLSTKLAK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: FA5_PIG
Sequence: MFPALPCPWVLVVLGTSWAAWGNLGTEAARVRQFYVAAQSISWNYHPEPTHPSSSPFATSFKKIVYREYEAYFQKEKPPSRMSGLLGPTLYADVGDIMKVHFRNKADKPLSIHPQGIKYSKFAEGASYPDHTFLVEKMDDAVAPGQEYTYEWNISEDSGPTHNDPPCLTHIYYSYENLIQDFNSGLIGPLLICKKGTLTEDGIQKMFDKQYVLMFAVFDESKSWNQSSSLMYTVNGYVNGTMPDITVCAYDHISWHLIGMSSGPELFSIHFSGQVLEQNHHKVSAITLVSATSTTANMTVSPEGKWPISSLIPKHFQAGMQAYIDIKNCAKKTRKPKKLTRDQRRHIKRWEYFIAAEEVIWDYAPIIPANMDKKYRSLHLDNFSNQIGKHYKKVVYKQYQDESFTKRLENPNNKEDGILGPVIRAQVRDTLKIVFKNMASRSYSIYPHGVTFSPYEDDVNSSSTSDNNTMIRAVQPGETYTYKWNILESDEPTENDAQCLTRPYYSNVDITRDIASGLIGLLLICKSRSLDKRGIQRTADIEQKAVFAVFDENKSWYIEDNIYKFCENPEKVKRDDPKFYESNIMSTINGYVPESIPTLGFCFDDTVQWHFCSVRTHDNILTIHFTGHSFIYGKRHEDTLTLFPMRGESVTVTMDNVGTWMLTTMNSNPRNKKLQLKFRDVKCIRDDDEDSYEIIYEPSSSTTLTTRKMHDSSENKEEENDDEYDYQDLLASVLGIRSFRNSSLYQEDDEFNLTALALENNSEFIPPSTDRAVDSNSSSPGNISRAPANTFTEPRKILPHPEATKAGSPRRHTGLVKNLVLNRRRTQHSDPYSEDPIENPLQSVITGISLLPFGTEGFRNREHPKHKRFKAGRDQAAKHRFSQMEFPAHKTGRHISQDNSSSSSMGPLEDLSSDLLLLERKDPSTINGKWHLVSEKGSYEIVQDADEDMAVNKLPNNPQNASRSWGENIPFTNKHGKQRGHPIFVTRHKLLQERQDEGNSILKKGRFFIRTRRKKKERKPVHHVPLSPRSFNPLRGEANTPFSDRRQNHSLLLHESNETFPPTDLNQTFPSMNLSLIASHPDHNQNLPNDTHQTSSPLDLYQTVTPDEPYQTAPIQDLDPTHSTAVPSHQSSLPEPIQMHDYDLRNKASPTDVSEMFFSLKLKAGHRTTSPDLNQTSLSPELSQTTLSPDPGHVTLSPDLSQTTLSPDLSHTTLSPDLGHTTLSPDLSHTTLSPDLSQTTLSPDLSHTTLSPDLGHTTLSPDLSHTTLSPDLGHATLSPDLSHTTLSPDLGHTTLSPDLGHTTLSPDFSQTTLSPDLGHTTLSSDVSHTTLSPDLSHTTLSPDLSHTTLSPDLGHTTLSPDLSQTTLSPDLGHMTLSPDLSHTTLSPDLGHTTLSPDLSHTTLSPDLGHMTLSPDLGQTTLSLDFGQTTLSPDLSHMTLSSELSHETLSPDLSQVTLSPDLSEIPFSPDLWQTTLSSDLNETTLSPDLRQTSPHPDPDKTSYISESSQSVTLPEFGQTSPFPDLGQRPSPPSHSTLNNTFIPREFNPMVVVGLSRDDGDYVEIIPRQQEENSEEDYVKIDYVEYDDPYQTDVRTDINSSRNPDNIAAWYLRSNNGNRRNYYIAAEELSWDYSKFTQREDIDDVPEHTIYKKVVFRKYLDSTFTKLDPRGEYEEHLGILGPIIRAEVDDVIQVRFKNLASRPYSLHAHGLSYEKSSEGKTYEDDSPEWFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVNPEKDIHSGLIGPLLICRKGTLHKENNMPVDMREFVLLFMVFDEKKSWYYEKKFTRSWRLTSSEVKNSHKFHAINGMIYNLPGLRMYEQEWVRLHLLNLGGSRDIHVVHFHGQTLLENGTQQHQLGVWPLLPGSFKTLEMKTSKAGWWLLDTEVGENQRAGMQTPFLIIDRECKMPMGLSTGLIADSQIKASEFWGHWQPKLARLNNGGSYNAWITDKFSGESNSKPWIQVDMQREVVFTGIQTQGAKYYLKSYYTTEFNVAYSSDQRNWRIFKGNSTKNVMYFNGNSDASTITENQFDPPVVARYIRISPTESYNKPALRLELQGCEVNGCSTPLGMESGNIKNEQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNNQWLQIDLLKIKKITAITTQGCKSLSSEMYVKRYTIQYSDRGVEWKSYREKSSMVDKIFEGNNNIKGHVKNFFNPPIISRFIRIIPKMWNQSIALRLELFGCDIY
What is the function of this protein?
Coagulation factor V is a cofactor that participates with factor Xa to activate prothrombin to thrombin.
What are the official names of this protein?
Coagulation factor V, Activated protein C cofactor.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSEB_HELPY
Sequence: MPNHQNMLDNQTILITGGTGSFGKCFVRKVLDTTNAKKIIVYSRDELKQSEMAMEFNDPRMRFFIGDVRDLERLNYALEGVDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINACLKNAISQVIALSTDKAANPINLYGATKLCSDKLFVSANNFKGSSQTQFSVVRYGNVVGSRGSVVPFFKKLVQNKASEIPITDIRMTRFWITLDEGVSFVLKSLKRMHGGEIFVPKIPSMKMTDLAKALAPNTPTKIIGIRPGEKLHEVMIPKDESHLALEFEDFFIIQPTISFQTPKDYTLTKLHEKGQKVAPDFEYSSHNNNQWLEPDDLLKLL
What is the function of this protein?
Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose.
What are the official names of this protein?
UDP-N-acetylglucosamine 4,6-dehydratase (inverting), Pseudaminic acid biosynthesis protein B, UDP-GlcNAc-inverting 4,6-dehydratase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide synthase family.
Protein: GLO2_METFK
Sequence: MFEIIPILAFEDNYIWLLHQHGHALVVDPGDAHPVLEILDARGLQLRAILVTHHHQDHTGGVEELIQATSAQVFAPAKEQFSFPHHPVTAGDRLDIPGIALSLSVLDVPGHTVGHVAYYGDGMLFSGDTLFGAGCGRLFEGTPGQMYSSLQQLAQLPVNTRVYCGHEYTERNLAFALSLEPHHEALLSRREATAALRAQGLPSLPSSMALELATNPFLRCHEPGIIAASKSAATDPVSVFAAIREMRNHF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: SLD5_RAT
Sequence: MTEVQDLHGQDSDEGSEEVVLTPAELIERLEQAWMNEKFAPELLESKSEIVECVMEQLEHMEENLRRAKKGDLKVSIHRMEMERIRYVLSSYLRCRLMKIEKFFPHILEKEKTRPAGEPSSLSPEEFVFAKEYMDHTETHFKNVALKHMPPNLQKVDLMRAVPKPDLDSYVFLRVKERQENILVEPEADEQRDYVIDLEEGSQHLIRYKTIAPLVASGAVQLI
What is the function of this protein?
Required for initiation of chromosomal DNA replication.  Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
What are the official names of this protein?
DNA replication complex GINS protein SLD5, GINS complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the GINS4/SLD5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm.
Protein: CDC6_METLZ
Sequence: MDSEPYKSTGLFKKYINPNKIFQNREVLRHSYSPKELPHRMDQIDSIAEILAPALQGATPSNILIYGKTGTGKTATVKFVGTELENESSEFSPCRLVHLNCETIDTQYRVLAQIANHVSGHDLKASDKIKNTIPATGWHTDQVYSELKNVLEQAGGLQIIVLDEIDKLVKKSGDDTLYNLTRINSDLFSSRVCIIGISNDLTFKDFLDPRVLSSLSEEELVFPPYNADQLRDILHQRAEMAFFPDVVSDEVIGLCAARAAQEHGDARRALDLLRVSGELAEREGAEHVMVKHVNSAQENIETDTMSECVKTLPSQSKIVLCSMLLMAASGQKVFTSGSVINVYREVAAELDTEALSHRRVSDLINELNMLGIITTRVVSHGRHGRTTEIYFKSPTNDIRTVIMNDSRFQECGILHPLLKSHEKGD
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.