PharMolix/UniProtQA huggingface dataset:
Protein: SYGB_ECO5E
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCD1_ARATH
Sequence: MEAKIVKVLDSSRCEDGFGKKRKRAASYAAYVTGVSCAKLQNVPPPNGQCQIPDKRRRLEGENKLSAYENRSGKALVRYYTYFKKTGIAKRVMMYENGEWNDLPEHVICAIQNELEEKSAAIEFKLCGHSFILDFLHMQRLDMETGAKTPLAWIDNAGKCFFPEIYESDERTNYCHHKCVEDPKQNAPHDIKLRLEIDVNGGETPRLNLEECSDESGDNMMDDVPLAQRSSNEHYDEATEDSCSRKLEAAVSKWDETDAIVVSGAKLTGSEVLDKDAVKKMFAVGTASLGHVPVLDVGRFSSEIAEARLALFQKQVEITKKHRGDANVRYAWLPAKREVLSAVMMQGLGVGGAFIRKSIYGVGIHLTAADCPYFSARYCDVDENGVRYMVLCRVIMGNMELLRGDKAQFFSGGEEYDNGVDDIESPKNYIVWNINMNTHIFPEFVVRFKLSNLPNAEGNLIAKRDNSGVTLEGPKDLPPQLESNQGARGSGSANSVGSSTTRPKSPWMPFPTLFAAISHKVAENDMLLINADYQQLRDKKMTRAEFVRKLRVIVGDDLLRSTITTLQNQPKSKEIPGSIRDHEEGAGGL
What is the function of this protein?
Inactive ADP-ribosyltransferase that functions with SRO1 to regulate oxidative stress, hormonal and developmental responses.  Required for embryogenesis, vegetative and reproductive development, and abiotic stress responses.  May regulate several stress-responsive genes.  Seems to play a larger developmental role than SRO1.  Does not bind NAD in vitro.
What are the official names of this protein?
Inactive poly [ADP-ribose] polymerase RCD1, Protein RADICAL-INDUCED CELL DEATH 1.
What are the subcellular locations of this protein?
Nucleus matrix. Note=Speckle-like pattern.
Protein: DEFI6_XENLA
Sequence: MSLRTELLKSVWYAFTSLDTEKSGKVSKSQLKVLSHNLYTVLCIPHDPVALEDHFRDDDDGPVSSQGYMPYLNQYILDKAVEGTFVKESLHELCWTLTAKKNYRPVQTALSNRDAFHLWCLFNYLSEDSYPVIMVADEVQYLLQKLLSIALMEVTEVELGDVLSSLSPVVTVWEFLQVMTSPKFLKSMSTETLSIAIQDLYEEVIQDVLKQGYLLKKANLRRTWTERWFILKPSSLGYYLSEECKERKGIITIDKDCGVEILPDRDGRRCMFCVKTTSKTHEMCASDTKHRQEWVTAIQTAIRLQQSGSLSLHRELQKRRREQRELREQRRAARELEMQRLAELQNEKERQQQELEQLREAQKKSEEIMLQEQHRHREQQEEMKRQLECQLREAEEARASMQAEMQLKETEAVQQKQRIQELEQLQDHLQEALAQEIRARHDEEAFRHAQSKLLMQEEEKLRVLLRMREEQTQYVERAQKEKQELQQEMAVTSKELQEAQKQLEDVRENRERADRDVQVAQKKLRQASTNVRHWNIQMNRLMHPISPGEKRIVSGSGFQGLWGIPFTRRDSSLKRLQTLDGKDHTHPAGEHVETFH
What are the official names of this protein?
Differentially expressed in FDCP 6 homolog.
Protein: COX5C_HORVU
Sequence: MAGGRVAHATLKGPSVVKEIFIGLTLGLVAGGMWKMHHWNEQRKTRSFYDMLEKGQISVVVEE
What is the function of this protein?
This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
What are the official names of this protein?
Cytochrome c oxidase subunit 5C, Cytochrome c oxidase polypeptide Vc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5C family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: ACP_BACCZ
Sequence: MADVLERVTKIIVDRLGVEETEVVPAASFKEDLGADSLDVVELVMQLEDEFEMEISDEDAEKIATVGDAVTYIESHL
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDQ_ENTLS
Sequence: MLLAHISDTHFRSQNHKLYGFIDVNAGNADVVSQLNGLRERPDAVVVSGDIVNCGRPEEYQVARQVLGALRYPLLLIPGNHDDKACFLEYLRPLCPQLGSDPQNMRYAIDDFATRLLFIDSSLAGHAKGWLTDNTVAWLEAQLSDAGDKPTAVFMHHPPLPLGNAQMDPIACENGHRLLALVERFPSLVRIFCGHNHNLTMTQYRQATIATLPATVHQVPYCHEDTRPYYDMSPPSCLMHRQVGEQWVSYQHSLAHYAGPWLYDEHISCPTDERRSPC
What is the function of this protein?
Catalyzes the hydrolysis of the 3'-5' phosphodiester bond of glycerophosphodiesters such as glycerophosphorylethanolamine (GPE), a typical phospholipid metabolite.
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase GpdQ, GDPD, Glycerophosphoryl diester phosphodiesterase, Glycerophosphodiesterase, Glycerophosphorylethanolamine phosphodiesterase, GPE phosphodiesterase.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: RL11_VIBC1
Sequence: MAKKVEAYIKLQVAAGMANPSPPVGPALGQHGVNIMEFCKAFNAKTESLEKGLPTPVVITVYNDRSFTFVTKTPPAAVLLKKAAGVKSGSGRPNTEKVGTVTDAQIQEIAETKAADMTGADIEAMKRSIAGTARSMGLVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DCYD_SALPA
Sequence: MPLHHLTRFPRLELIGAPTPLEYLPRLSDYPGREIYIKRDDVTPIAMGGNKLRKLEFLVADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDVLTDPDAQLQTLATRIEAQGFRPYVIPVGGSSALGAMGYVESALEIAQQCEEVVGLSSVVVASGSAGTHAGLAVGLEHLMPDVELIGVTVSRSVAEQKPKVIALQQAIAGQLALTATADIHLWDDYFAPGYGVPNDAGMEAVKLLASLEGVLLDPVYTGKAMAGLIDGISQKRFNDDGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: RR14_LACSA
Sequence: MAKKSLIQREKKRQKLEQKYHLIRRSSKKEISKVRSLSDKWEIYGKLQSPPRNSAPTRLHRRCFSTGRPRANYRDFGLSGHILREMVHACLLPGATRSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFG_CORU7
Sequence: MALEALTDLKKVRNIGIMAHIDAGKTTTTERILFYTGINRKVGETHDGASTMDWMEQEKERGITITSAATTCFWNDNQINLIDTPGHVDFTVEVERSLRVLDGAVAVFDAKEGVEPQSEQVWRQADKYDVPRLCFVNKMDKLGADFYHTVQTIIDRLGAKPLVMELPIGAEDDFEGVVDLLQMKALMWPGVVAAGTEPTIEEIPADLQEKAEEYREKLIEAVAESDEELMERYFAGEEITVDEIKKQIRHLTINGEAYPVFCGTAYKNKGIQPILDAIIDYLPNPMDVGSIKGFDPKDREIERNRKPSRDEPFSALAFKVAVHPFFGKLTYVRVYSGSVETGDKIINSTKNKPERVGKLFQMHSNKEQPVDRASAGHIYAFIGLKDTSTGDTLSDSANPVVLEDMDFPDPVIEVAIEPKTKSDQEKLGTAIQKLAEEDPTFTVKLDEETGQTVIGGMGELHLDVLVDRMKREFKVEANVGAPQVAYRETIKKPVEKLEYTHKKQTGGSGQFARVIIALEPLVPEEGSEETYEFIDEVTGGRIPKEYIPSVDQGIQDAMQYGYLAGFPLVNIKATLLDGAYHEVDSSEMAFKLAGSMALKEAVAKAKPVLLEPMMAVEIITPEEYMGEVIGDVNSRRGSVSSMEDRSGAKVVKARVPLSQMFGYVGDLRSKTQGRANYSMIFDSYAEVPQNVAEEIIAERTGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIAC1_DICDI
Sequence: MKIFIIISLILTILIIQSKSKECPCSNVELCKPLEIGPRKEFIGFSVNSTFYPYYNWDHLTTIGIFYSEDIEDELLCMAKTNGVRLVYSAFYPVEQLSNETYIDQWINEKLELVQNTFTDGLNFDVEYPITDPIVAQQYTQLVAATNNAFKSVNLYYQISVDVAWDASNCIDYRCYDYLGLSKASDFLVVMDYDMKLDGYYFKTCLASANSPPSSVLSGMVNFTKLGIDESSLVMGLPWYGYNYPCIGSNYTLQTFECIIPPSSYLGYNCTDASGIEINYSIIMNMLNDTAIQNGGVQWDSESESPYFNFIDLFSGTQHQMWFDNPDSLTIKVNIARTMNLRGVGVWNIDQLWDDHSLSSGMWGALNSFFKIN
What is the function of this protein?
Involved in the degradation of asparagine-linked glycoproteins.  May hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N-acetylglucosamine chitobiose core from the reducing end of the bond.
What are the official names of this protein?
Probable di-N-acetylchitobiase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: THIM_ACIB3
Sequence: MNSTSNLIEQVIEAWQNMQAKTPLVQCITNSVAANYTANVLLASGASPAMIDNPYEAESFTKISSALSINLGTPTSEQMQAMQISAKTAQLNNVPWVLDPVGYGPILAWRSQMTDELLQFKPSVIRGNASEISTLAGNQVQSKGVDSTLSSDQAYQQAFSLLTHASCIAISGESDYILSNEVDAVIQVNGGSPLQPKITATGCALGALIAAYSAVTTPTIAALSAHIHFAIAGKLAANQAQTMGSFSSIFMDYIHMLDANLIEQYADVKLLNKQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: PCKA_VIBCH
Sequence: MTVMEHTKAAQIDLAQYGITGVTELVRNPSYEMLFAEETRSDLEGYERGVVTELGAVAVDTGIFTGRSPKDKFIVKDDTTRDTLWWTSDKAKNDNKPINQEVWNDLKALVTKQLSGKRVFVLDGYCGANADTRLSVRFITEVAWQAHFVKNMFIRPSEEELAHFKPDFVVMNGAKCTNAKWKEHGLNSENFTVFNLTERMQLIGGTWYGGEMKKGMFAMMNYFLPLQGIASMHCSANMGKAGDVAIFFGLSGTGKTTLSTDPKRALIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPDIYNAIRRDALLENVTVRSDGSIDFDDGSKTENTRVSYPIYHIDNIVKPVSKGGHATKVIFLSADAFGVLPPVSKLTPEQTKYHFLSGFTAKLAGTERGITEPTPTFSACFGAAFLTLHPTQYAEVLVKRMEAAGAEAYLVNTGWNGSGKRISIKDTRGIIDAILDGSIEKAETKHIPIFNLQVPTALPGVDPMILDPRDTYVDPLQWESKAKDLATRFINNFDKYTDNAEGKALVAAGPKLD
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMPK_MOUSE
Sequence: MSAEVRLRQLQQLVLDPGFLGLEPLLDLLLGVHQELGASHLAQDKYVADFLQWVEPIAARLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLQPDGMVRSLVAVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPLADTVVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFFFGLDWEGLRDSVPPFTPDFEGATDTCNFDVVEDRLTAMVSGGGETLSDMQEDMPLGVRLPFVGYSYCCMAFRDNQVPDPTPMELEALQLPVSDLQGLDLQPPVSPPDQVAEEADLVAVPAPVAEAETTVTLQQLQEALEEEVLTRQSLSRELEAIRTANQNFSSQLQEAEVRNRDLEAHVRQLQERMEMLQAPGAAAITGVPSPRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARIPRPGLSEARCLLLFAAALAAAATLGCTGLVAYTGGLTPVWCFPGATFAP
What is the function of this protein?
Non-receptor serine/threonine protein kinase which is necessary for the maintenance of skeletal muscle structure and function.  May play a role in myocyte differentiation and survival by regulating the integrity of the nuclear envelope and the expression of muscle-specific genes.  May also phosphorylate PPP1R12A and inhibit the myosin phosphatase activity to regulate myosin phosphorylation.  Also critical to the modulation of cardiac contractility and to the maintenance of proper cardiac conduction activity probably through the regulation of cellular calcium homeostasis.  Phosphorylates PLN, a regulator of calcium pumps and may regulate sarcoplasmic reticulum calcium uptake in myocytes.  May also phosphorylate FXYD1/PLM which is able to induce chloride currents.  May also play a role in synaptic plasticity.
What are the official names of this protein?
Myotonin-protein kinase, MT-PK, DM-kinase, DMK, DMPK, Myotonic dystrophy protein kinase, MDPK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum membrane. Cell membrane. Note=Localizes to sarcoplasmic reticulum membranes of cardiomyocytes. SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum membrane; Single-pass type IV membrane protein; Cytoplasmic side. Nucleus outer membrane; Single-pass type IV membrane protein; Cytoplasmic side. SUBCELLULAR LOCATION: [Isoform 8]: Mitochondrion outer membrane; Single-pass type IV membrane protein. SUBCELLULAR LOCATION: [Isoform 5]: Cytoplasm, cytosol.
Protein: FADR_SALHS
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTALRQHPDKAQEVLATAHEVADHADAFADLDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSSLCEQGAHDQVYETVRRYGHDSGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_THEPX
Sequence: MLRTYQPKKRHRKKVHGFRKRMSTKSGRNVLKRRRQKGRHRLTA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TRIM5_PONAB
Sequence: MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSTLDKGERSCPVCRVSYQPKNIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCKEDGKVICWLCERSQEHRGHHTFLTEEVAQKYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTSVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTKSETEMVQQTQSVRELISDVEHRLQGSVMELLQGVDGIIKRMQNVTLKKPETFPKNQRRVFRAPNLKGMLEVFRELTDVRRYWVDVTVAPNDISYAVISEDMRQVSCPEPQITYGAQGTTYQTYVNFNYCTGILGSQSITSGKHYWEVNVSKKSAWILGVCAGFQPDAMYNIEQNENYQPQYGYWVIGLEEGVKCSAFQDGSFHNPSAPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPRKCRVPMTLCSPSS
What is the function of this protein?
Capsid-specific restriction factor that prevents infection from non-host-adapted retroviruses.  Blocks viral replication early in the life cycle, after viral entry but before reverse transcription.  In addition to acting as a capsid-specific restriction factor, also acts as a pattern recognition receptor that activates innate immune signaling in response to the retroviral capsid lattice.  Binding to the viral capsid triggers its E3 ubiquitin ligase activity, and in concert with the heterodimeric ubiquitin conjugating enzyme complex UBE2V1-UBE2N (also known as UBC13-UEV1A complex) generates 'Lys-63'-linked polyubiquitin chains, which in turn are catalysts in the autophosphorylation of the MAP3K7/TAK1 complex (includes TAK1, TAB2, and TAB3).  Activation of the MAP3K7/TAK1 complex by autophosphorylation results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes, thereby leading to an innate immune response in the infected cell.  Plays a role in regulating autophagy through activation of autophagy regulator BECN1 by causing its dissociation from its inhibitors BCL2 and TAB2.
What are the official names of this protein?
Tripartite motif-containing protein 5, RING-type E3 ubiquitin transferase TRIM5, TRIM5alpha.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly localizes in cytoplasmic bodies. Localization may be influenced by the coexpression of other TRIM proteins, hence partial nuclear localization is observed in the presence of TRIM22 or TRIM27. In cytoplasmic bodies, colocalizes with proteasomal subunits and SQSTM1.
Protein: PNP_SHESH
Sequence: MVHVNPIVKSFEYGQHTVTLETGVIARQADAAVLASMGDTTVLVTVVGKKFEEPGRDFFPLTVNYQEKTYAAGKIPGGFFKREGRPSESETLIARLIDRPIRPLFPNGFKNEVQVIITVVSVDPEINPDVISMIGTSAALAISGLPFNGPLGVARVGYTDGEYVLNPNVSQLVDSDLDLIVAGTQGAVLMVESEAAALPEEVMLGGVVYGHDQQQVVISAINELKAEASKPAWDWTAPVQDADLVAKIKDLAEAEMAAAYQIEVKQDRYTQVGVVKSAAKEALLAENPEADLREIDGLLGSLEKQVVRSRIIAGNPRIDGREPDMVRGLNVMAGVLPRTHGSALFTRGETQALVTCTLGTERDAQKVDSIMGEYTNRFMLHYNFPPYSVGETGFVGSPKRREIGHGKLAWRGINAVMPSAEEFPYSVRVVSEITESNGSSSMASVCGTSLALMDAGVPIKTSVAGIAMGLVKEGDDFVVLSDILGDEDHLGDMDFKVAGTRDGITALQMDIKIEGINKEIMQIALQQAYGARVHILNVMDQAIGEHRDDISDHAPRITTLKINPEKIRDVIGKGGATIRALTEETGTTIELEDDGTVKIASANGDATKEAIRRIEEITAEVEVGTIYNGKVVRIVDFGAFVTILPGKDGLVHISQIAEERVANVSDYLQVGQEVKVKVMEVDRQGRVRLSMKEAAPKAEAAPAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISCR_SALDC
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDAGSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRASGRAQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: PSAJ_GNEPA
Sequence: MQDIKTYLSTAPVLATFWFGLLAGLLIEINRFFPDALTFSFAF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RTCA_SACS2
Sequence: MIEIDGSFGEGGGQILRTSLTLSVITGKPFRIFNIRANRPNPGLQRQHLWAVRAMKMISNAETKGDEVGSKELTFIPHEIKGNSIIDIDIGTAGSVTLIMQTMIPAIINKNMRIKIKGGTDVPKSPTIDYIRLVYLEILRKIGIESKVNLIKRGHYPEGGGEVIIENVNGNPSDFSLLELGKLIMIKGISHVSSLPSHIAERQKDSAKAILSKLGVQIEIETDVRQGEVSKGSGIALAAIGEKSIIGADSLGERGKRAEIVGEEAARKLIDNLNTKAAVDVHMSDMLMIFTSLFGGEYIGAELTSHAYTNMEIIRKFLDVKIEISGKRPFRFKAKIF
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP30L_DANRE
Sequence: MNGFSTEEDSHDGPPAPPFFGQSCCLIEDAERCGRPAGNASFSKRIQKSISQRKLKLDIDKSVRHLYICDFHKNFIQSVRNKRKRKTSDDGGESPDHEVEVPEVDLFQLQVNTLRRYKRHYKIQTRPGLNKAQLAETVSRHFRNIPVNEKETLTYFIYMVKSSKSRLDQKSDSSKQVE
What is the function of this protein?
Functions as transcription repressor, probably via its interaction with histone deacetylase complexes (PubMed:22821512).  Required for normal expression of numerous target genes (PubMed:22821512).  Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus.  Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA.  Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import (By similarity).
What are the official names of this protein?
Histone deacetylase complex subunit SAP30L, Sin3 corepressor complex subunit SAP30L, Sin3-associated protein p30-like.
What is the protein family that this protein belongs to?
Belongs to the SAP30 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: INT11_MOUSE
Sequence: MPEIRVTPLGAGQDVGRSCILVSISGKNVMLDCGMHMGYNDDRRFPDFSYITQSGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRTFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQMLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLRQKIEQEFRVSCYMPANGETVTLPTSPSIPVGISLGLLKREMVQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLQDTRKEQETALRVYSHLKSTLKDHCVQHLPDGSVTVESILIQAAAHSEDPGTKVLLVSWTYQDEELGSFLTTLLKNGLPQAPS
What is the function of this protein?
Catalytic component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates the snRNAs 3' cleavage.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex.
What are the official names of this protein?
Integrator complex subunit 11, Int11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CHS1_SECCE
Sequence: MAATMTVEEVRKAQRAEGPATVLAIGTATPANCVYQADYPDYYFKITKSDHMADLKEKFKRMCDKSQIRKRYMHLTEEILQDNPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPHEFDSLVGQALFGDGAAAVIVGADPDESVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEDAFKPLGIDDWNSVFWIAHPGGPAILDMVEAKVNLNKERMRATRHVLSEYGNMSSACVLFIMDEMRKRSAEDGHTTTGEGMDWGVLFGFGPGLTVETVVLHSVPVTA
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 1, Naringenin-chalcone synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: ACUK_UNCRE
Sequence: MTSNARNGPLPPNPLANSGNNRDISADITMAEQVVRPESQTQVENSSTKQPNGQTKPMSASNAKDPLRPRRKKAKRACFACQRAHLTCGDERPCQRCIKRGIQNSCHDGVRKKAKYLHDAPNEALMPHLQGQLYTQTNAVRNNMSLTSNGSNSKTNFYPRQNSNFNGYYATKNDGSLSQSQLHDAGRPDTFPSQSPVSPTFSITANSATSGNQNMPSSLPASNGNASGQAQNGFGSAFFDPCDPALFNFDLASMNFGNHYGALEFGMLGHMATGAGDTPPSDSATQHGSVGRNGSGTFAPGSNFGESPTAQPSFLFGDPTIAGDWSSSVHTRNIYNQNMNHMSETPHAFAIESGPANFASPNSIESPLLTNSATFDDNTTSAYQNRSSMNPMPPQRQPVVSTPQLKHLQLSKRRQRNPSAIYESVKEPYSYTTGFHSLTAFIQRRFSTQNTLRIAKALASIRPSFIATTKTLNRDDLIFMEKCFQRTLWEYEDFINACGTPTIVCRRTGEIAAVGKEFSILTGWRKEVLLGKEPNLNINTGGSSGSTSGTSSRGSFTPRAGMEVNPSGRTQPVFLAELLDDESVVEFYEDFAKLAFGDSRGSVMTTCKLLKYKTKADTDMLPGNTGGTGGGDGQSAASGNGHVKVENGMAASNGQAQPLSQPQRRWSRGGIAGEAGMNQLGFKDGKVECSYCWTVKRDVFDIPMLIVMNFLPCI
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis UREG_00958.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.