PharMolix/UniProtQA huggingface dataset:
Protein: PA2A2_WALAE
Sequence: AVCVSLLGASSIRPLPLHLGQFNNMIKCTIPGSTPWWDFSDYGCYCGYGGSGTPVDQLDRCCQTHDNCYTEAQKFSGCSPYRRKYSYECSEGTLTCKSDNDECAAFVCNCDRLAAICFAGAPYNSNNVDIDLEARCQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that may act in the hemostasis system of the prey (By similarity).  Exhibits hydrolytic activities, and prefers the anionic micelles (dPPC with deoxycholate) (54 umol/mg/min) to the zwitterionic micelles (dPPC with Triton X-100) (15 umol/mg/min).  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 PL-II, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HPPK_BACSU
Sequence: MNNIAYIALGSNIGDRETYLRQAVALLHQHAAVTVTKVSSIYETDPVGYEDQAQFLNMAVEIKTSLNPFELLELTQQIENELGRTREVRWGPRTADLDILLFNRENIETEQLIVPHPRMYERLFVLAPLAEICQQVEKEATSAETDQEGVRVWKQKSGVDEFVHSES
What is the function of this protein?
Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.
What are the official names of this protein?
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, PPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK.
What is the protein family that this protein belongs to?
Belongs to the HPPK family.
Protein: ACCA_STRPD
Sequence: MTDVSRVLKEARDQGRLTTLDYANLIFDDFMELHGDRHFSDDGAIVGGLAYLAGQPVTVIGIQKGKNLQDNLARNFGQPNPEGYRKALRLMKQAEKFGRPVVTFINTAGAYPGVGAEERGQGEAIAKNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQVWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAGELYQMGIVDRIIPEHGYFSSEIVDIIKANLIEQITSLQAKPLDQLLDERYQRFRKY
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXVE_BITAR
Sequence: MAAYLLAVAILFCIQGWPSGTVQGEVRPFMEVYQRSVCQPRETLVSILEEYPDKISKIFRPSCVAVLRCGGCCSDESLTCTSVGERTVELQVMQVTPKTLSSKIKVMKFREHTACECRPRSGSRVNIGKHKRSPEEGEREPSSPLTPGSL
What is the function of this protein?
Snake venom VEGFs that may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension.  This protein induces an increase in capillary permeability after intradermal injection, as well as a drastic hypotensive effect after intravenous injection.  The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase.  Also induces angiogenesis in vitro, probably through VEGF receptor (KDR/VEGFR-2) signaling.
What are the official names of this protein?
Snake venom vascular endothelial growth factor toxin barietin, svVEGF, VEGF-F.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MIAB_AGRFC
Sequence: MIAREGSNSRKVFIKTYGCQMNVYDSVRMSDALAKDGYVQTEDMGEADLVLLNTCHIREKAAEKVYSALGRLRDMKKSREEQGREFMIGVAGCVAQAEGEEILRRAPAVDVVIGPQTYHRLPDALKRVRRGERVIETEYAVEDKFEHLPVAEKATLRSRGVTAFLTVQEGCDKFCTFCVVPYTRGSEVSRPVRQIVDEAMKLVDAGVREITLLGQNVNAWQGEGPKGEKWGLAELLYRLAEIPGLARLRYTTSHPRDMDDRLIGAHRDLRILMPYLHLPVQSGSDRILKAMNRRHTGEEYIQLIEKIRSARPDIAMSGDFIVGFPGETDRDFEDTMAMVETVKYAQAFSFKYSTRPGTPGADLTDQVAEDVKAERLERLQALLLRQQKEFAESLVGKTMDVLLEKPGRMPEQLIGRSPWLQSVNLDAKTLKIGDIVNVRITATGPNSLFAEVAGS
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_AROAE
Sequence: MIDEAIVQFDKALRTLFAPARSVRPTPGAGVPETHLGDRDRQHVAALMRVNHSGEICAQALYQGQSMSAGDLDVKRELARASDEETEHLAWTEQRISELGGRKSLLNPLWYGGSLALGLLAGRLGDRWSLGFLAETERQVEAHLDGHLEHLPPEDHKSREIIEQMKADEAHHADVALALGAHELPAPFRGAMRLMARVMTATAYRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: H2A2A_HUMAN
Sequence: MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 2-A, H2A-clustered histone 18, H2A-clustered histone 19, Histone H2A.2, Histone H2A/o.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CH10_ECO57
Sequence: MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
Protein: IMA4_HUMAN
Sequence: MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLLSVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEIIDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF
What is the function of this protein?
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1.  Binds specifically and directly to substrates containing either a simple or bipartite NLS motif.  Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.  At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin.  The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.  In vitro, mediates the nuclear import of human cytomegalovirus UL84 by recognizing a non-classical NLS.  Recognizes NLSs of influenza A virus nucleoprotein probably through ARM repeats 7-9.
What are the official names of this protein?
Importin subunit alpha-4, Importin alpha Q2, Qip2, Karyopherin subunit alpha-3, SRP1-gamma.
What is the protein family that this protein belongs to?
Belongs to the importin alpha family.
Protein: CBID_SALHS
Sequence: MSELSFDAPVWHHGKALRKGYTTGSCATAAAKVAALMVLRQHLIHQVSIVTPSGVTLCLNVESPHIEGQQAIAAIRKDGGDDVDATHGMLIFARVTLNDSGEITLTGGEGIGTVTRKGIGLPLGSAAINRTPRHTIESAVREAIGPARGADVEIFAPEGEVRAQKTYNSRLGILGGISIIGTTGIVTPMSEESWKRSLSLELEIKRASGLTRVILVPGNHGERFVREQMGVDTQAVVTMSNFVGYMIEEAVRLGFCQIVLVGHPGKLIKIAAGIFHTHSHIADARMETLVAHLALLGAPLELLTLVSDCDTTEAAMEHIEAYGFGHIYNHLARRICLRVMQMLRFTKTQPVCDAILFSFDNHILGSNRPVDEIAKELQC
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: SYV_SHIDS
Sequence: MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKAADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHAYMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPSSVMVSGFDIIFFWIARMIMMTMHFIKDENGTPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTHHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHE1_CHEAL
Sequence: MAKCQAVFLLVGALCVLSLAGVANAAENHFKVQGMVYCDTCRIQFMTRISTIMEGATVKLECRNITAGTQTFKAEAVTDKVGQYSIPVNGDFEDDICEIELVKSPNSECSEVSHDVYAKQSAKVSLTSNNGEASDIRSANALGFMRKEPLKECPEVLKELDLYDVKAN
What are the official names of this protein?
Pollen allergen Che a 1.
What is the protein family that this protein belongs to?
Belongs to the Ole e I family.
What are the subcellular locations of this protein?
Secreted.
Protein: URE2_BURO1
Sequence: MIPGEILTDDGEHELNAGRATLSLVVANTGDRPVQVGSHYHFFEVNDALSFDRAAARGFRLNIAAGTAVRFEPGQTRTVELVALAGERAVYGFQGKVMGPL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
Protein: UXAC_ECO7I
Sequence: MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDPIDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
What are the official names of this protein?
Uronate isomerase, Glucuronate isomerase, Uronic isomerase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.
Protein: RLME_PECCP
Sequence: MANKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGNGRIIACDILPMDPIVGVDFLQGDFRDELVLKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPKSMYLVELALGMCRDVLAPGGSFLVKVFQGEGFDEYLREIRSLFTKVKIRKPDASRARSREVYIVATGRKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPC_RHILV
Sequence: MCLAIPVQVKELLPDNMAKVTLDGVSKIVSTALVDDVKVGDYVVLHVGYALAKIDPEEAERTLALIRERAMGDAA
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Involved in the biosynthesis of the Fe(CN)(2)CO cofactor.
What are the official names of this protein?
Hydrogenase maturation factor HypC.
What is the protein family that this protein belongs to?
Belongs to the HupF/HypC family.
Protein: PP398_ARATH
Sequence: MESSKLLSLLRECTNSTKSLRRIKLVHQRILTLGLRRDVVLCKSLINVYFTCKDHCSARHVFENFDIRSDVYIWNSLMSGYSKNSMFHDTLEVFKRLLNCSICVPDSFTFPNVIKAYGALGREFLGRMIHTLVVKSGYVCDVVVASSLVGMYAKFNLFENSLQVFDEMPERDVASWNTVISCFYQSGEAEKALELFGRMESSGFEPNSVSLTVAISACSRLLWLERGKEIHRKCVKKGFELDEYVNSALVDMYGKCDCLEVAREVFQKMPRKSLVAWNSMIKGYVAKGDSKSCVEILNRMIIEGTRPSQTTLTSILMACSRSRNLLHGKFIHGYVIRSVVNADIYVNCSLIDLYFKCGEANLAETVFSKTQKDVAESWNVMISSYISVGNWFKAVEVYDQMVSVGVKPDVVTFTSVLPACSQLAALEKGKQIHLSISESRLETDELLLSALLDMYSKCGNEKEAFRIFNSIPKKDVVSWTVMISAYGSHGQPREALYQFDEMQKFGLKPDGVTLLAVLSACGHAGLIDEGLKFFSQMRSKYGIEPIIEHYSCMIDILGRAGRLLEAYEIIQQTPETSDNAELLSTLFSACCLHLEHSLGDRIARLLVENYPDDASTYMVLFNLYASGESWDAARRVRLKMKEMGLRKKPGCSWIEMSDKVCHFFAEDRSHLRAENVYECLALLSGHMESGQ
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g27110.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
Protein: RRF_CUPPJ
Sequence: MSVAETKKSVEQKMQKSIEAFKADLAKVRTGRAHVGLLDHVQVDYYGSMVPISQVANIGLGDARTITVQPWEKKMVGAVEKAIRDCDLGLNPATMGEVIRVPMPPLTEERRKELTKVVKGEAEGAKIAVRNLRRDANEQFKKLVKDKAISEDDERRGQDDVQKLTDKYVAEIDKMVAEKEKEIMTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLS2_CAEEL
Sequence: MTSKPTTQKSVMYRIPSERTLESLHEMIGSRMSKMSLKNTLRGISNPYERDENEGSEDMIFELFKIPNKNEASIGKLLTVLRQLGLRDDDPRLVPMMEKIKDFEKIAEEKCSEATEQKHWKLTKEQFKECIAPSIDIVSRALQTDMVIPNWVTFVDQIRTLFNECKEIREGQVATYIPQLARQSPNLWAVSLCTVDGQRASFGDVKHPFCVQSVSKAFNYAIVASDLGADVVHSYVGQEPSGRLFNEICLDSTNKPHNPMVNSGAIVITSLIKSKTNMADRFDFVLNQYRKIAGNEFIGFNNATFLSERATADRNYALSYFMKENRCFPKETESLTDALDFYFQLCSVEVTCESLAVMASTLANGGVCPITNETCVDPNPCRDVLSLMYSCGMYDASGQFSFNVGLPAKSGVSGAMIVVVPNVMGICLFSPPLDSLGNSCRGVAFCKKLVSTFNFHNYDCLVHNSNIKSDPRRRDIRERDRLIPVFHVARAGDLPTMRRLYMQGEDLNTSDHDDRTVLHIAATEGYETMIKFLVNVAKVDVDKKDRWGRTPLDEAKFFKHDHVSRFLEKAMKRPEQHRKDSVSSLDTDDEIDDDGFPEKPSFTID
What are the official names of this protein?
Putative glutaminase 2, GLS, L-glutamine amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: ERG27_YARLI
Sequence: MIHNRKTQTVVITGASSNLGIAIGKRLIDEKKEDAHLTIVVTSRTLRNVRVAIKTLKAHAVAKEVGPEVDFDYLLFDLADMTSINGALVELKLRFSRIDTLIFNSNAANYIGINWPLAMWRFTTQFKSEIENPSCMIQAVGVKSDDGMGSAYQSNVFGPWYMVLELTEQLKNGGKVIWISSITSSEKYVDLEDIELIHNKEPYKGSKRLIDVAHNYYSPKLEEEHGIYSYLTDPGIFTSSSASEYLNIFSAFGMYLMFYFARLIGLTTMNIDPYKGANVPVWVTLSEDPSALKREYRLGSRTGRWGTEMMDATKLQYEGSEEVGAYIDKGVGEWREKLKDQIN
What is the function of this protein?
Responsible for the reduction of the keto group on the C-3 of sterols.
What are the official names of this protein?
3-keto-steroid reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.
Protein: HIS4_ACTP2
Sequence: MQKKSIIIPALDLIDGNVVRLHQGDYAKQTTYSDNPIEQFANYLAQGAEQLHLVDLTGAKYPAKRQTALIGKIIAETNCQIQVGGGIRTEQDVADLLAVGANRVVIGSTAVKDRAMVKGWFEKYGAEKFVLALDVNIDASGQKIIAISGWQEASGVSLEELIEDYQVVGLQHVLCTDISRDGTLAGSNVNLYREICAKYPKIHFQSSGGIGSLDDIKALKGTGVSGVIVGRALLEGKFNVAEAIECWQNG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_ACTPJ
Sequence: MPRRRSVEPRKILPDPKFGSELLAKFINVLMVDGKKSTAESIIYGALETLAQRTGKEALEAFEAALENVRPTVEVKSRRVGGSTYQVPVEVRPSRRNALAMRWIVEAARKRGDKSMALRLANELSDAADNKGTAVKKREDVHRMAEANKAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: LAC2_CRYNH
Sequence: MGGIIKLSFLFCSLISLVNSENTGKLPTAISDHSVPKATATTDPSVFVLSNDFEITDVPTTREYTFNLTEALASPDGYERLVYAVNNMLPGPVIEANTGDTVIVHVNNYLHEGQGIHWHGLRQNGTALMDGVPGITQCSIPPGGSFTYQFTVSHQSGTFWWHSHYSNSMADGIWGPLIVHSPNEPLQRGRDYDEDRIVAVTDWMHDESETIVEALISSEGYRGRPFPPQGDAILINGRGQTNCTATGSPSCTYPPPPEIHVPVNCRVRLRFISAASHPMYRISIDNHSMEIVETDGTAVYGPTIHEISISSGERYSVIINTTEGKEGDAFWLRTSVALDCMAQGVTQVGLAVVRYTGNGSITTAEPRTEAWTDLARPDTPCVGLDEMYHLSPRELVNASQTALESRVLDSKLGKFVDVYGNSFEGYGFNNVTYQNQINDPLLYVVQRGGTCNSSLIANATFADIGPVNIIINNLDSHIGHPYHMHGTEFQLMGRGTGALTLDDLPNTNLTLDNPTRKDTIWMQGGSWALLRIISDNPGVWALHCHIGWHLAKGKMAVVVVQPEAIKKIQWPESWMDLCANTDPNAFGPARRSVS
What is the function of this protein?
Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (By similarity).  Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (By similarity).  Plays an important role in virulence (By similarity).  Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (By similarity).
What are the official names of this protein?
Laccase-2, Diphenol oxidase 2.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
Protein: NDHN_TRIEI
Sequence: MALITTGRGMIRDLEKSGSLAVYPPLEGGFEGRYQRRLRASGYVSESITARGLGDLAMYLTGVHGVRPPHLGKKTVGNGPAVGYVYYVPPIVNYKLEHLPPKAKGLVLWIMEGQILSSQEIEYLTVLPKSEPRVKVIVEMGGDRFFRWTPLQNTLVPA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit N, NAD(P)H dehydrogenase I subunit N, NDH-1 subunit N, NDH-N.
What is the protein family that this protein belongs to?
Belongs to the complex I NdhN subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1405_MYCTU
Sequence: MTIDTPAREDQTLAATHRAMWALGDYALMAEEVMAPLGPILVAAAGIGPGVRVLDVAAGSGNISLPAAKTGATVISTDLTPELLQRSQARAAQQGLTLQYQEANAQALPFADDEFDTVISAIGVMFAPDHQAAADELVRVCRPGGTIGVISWTCEGFFGRMLATIRPYRPSVSADLPPSALWGREAYVTGLLGDGVTGLKTARGLLEVKRFDTAQAVHDYFKNNYGPTIEAYAHIGDNAVLAAELDRQLVELAAQYLSDGVMEWEYLLLTAEKR
What are the official names of this protein?
Uncharacterized protein Rv1405c.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv1403c.
Protein: PANC1_BRADU
Sequence: MKVITKVAELRRALADVRNAEKRIGFVPTMGYLHDGHLALISASREHCDVTVVSIFVNPTQFGPNEDLSRYPRDFARDEALCGSAGVSIIFAPSAEEIYPAQFESFVEPGELAKPLCGAFRPGHFRGVATVVCKLFNMVQPDVAYFGQKDFQQCAVIRRMTVDLNLPIEIVTVPTVREPDGLAMSSRNRYLCPEERDRSLAISRGLFAAAHEFASGERDAATLIALARRHLERVDRLQYLELVDPGTLRIADSPLRYPAVLCVAAYVGSTRLIDNVVLSWSPS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase 1, PS 1, Pantoate--beta-alanine ligase 1, Pantoate-activating enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_PSEPF
Sequence: MNDFTLNAELRSDLGKGASRRLRRLAALVPAVVYGGDKAPESISMLAKEVAKLLENEAAYSHVIELNVGGTKQNVIIKALQRHPAKGHVMHADFVRVVAGQKLTAIVPVHFINEAAPVKKGGEISHVVAEIEVSCLPKDLPEFIEVDLANAEIGTIVHLSDIKAPKGVEFVALAHGDDKAVANVHAPRVAPEATEEGAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: Y1603_STAAB
Sequence: MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIKLNAIVVKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFNKKTKQGVPFIYDEHTAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSYTTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRNKTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEANRRKFNKDK
What are the official names of this protein?
UPF0354 protein SAB1603c.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.
Protein: YCF33_GUITH
Sequence: MPTFWENLIRYPRFFISSTLGLVFIITGPLFNLLNKPKSALLFAIIVFGILSGLLITLLLMLDII
What are the official names of this protein?
Uncharacterized protein ycf33.
What is the protein family that this protein belongs to?
Belongs to the ycf33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.