PharMolix/UniProtQA huggingface dataset:
Protein: IF2G_RABIT
Sequence: AGGEAGVTLGQPSLVEQDSHSGFKNELERDGGLLLIAGNESKLKHILILGNKIDLVKESQAKEQYGQILAFVQETVAXGATVGQVLGAVGALPEIFTELXIVNIGSLSTGGQVSAVKADLGKIVLTNPVXTEVGEEKSVEKHWRLIGWGQIR
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.  This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex.  Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex.  In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
What are the official names of this protein?
Eukaryotic translation initiation factor 2 subunit 3, Eukaryotic translation initiation factor 2 subunit gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EIF2G subfamily.
Protein: GYRB_PSEAE
Sequence: MSENNTYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNSIDEALAGYCSEISITIHTDESITVRDNGRGIPVDIHKEEGVSAAEVIMTVLHAGGKFDDNTYKVSGGLHGVGVSVVNALSHELRLTIRRHNKVWEQVYHHGVPQFPLREVGETDGSGTEVHFKPSPETFSNIHFSWDILAKRIRELSFLNSGVGILLRDERTGKEELFKYEGGLKAFVEYLNTNKTAVNEVFHFNVQREEDGVGVEVALQWNDSFNENLLCFTNNIPQRDGGTHLAGFRSALTRNLNNYIEAEGLAKKFKIATTGDDAREGLTAIISVKVPDPKFSSQTKDKLVSSEVKTAVEQEMGKYFADFLLENPNEAKAVVGKMIDAARAREAARKAREMTRRKGALDIAGLPGKLADCQEKDPALSELYIVEGDSAGGSAKQGRNRRTQAILPLKGKILNVEKARFDKMLSSQEVGTLITALGCGIGREEYNIDKLRYHNIIIMTDADVDGSHIRTLLLTFFFRQMPELIERGYIYIAQPPLYKVKRGKQEQYIKDDQAMEEYMTQSALEDASLHVNEHAPGLSGAALEKLVNEYRGVIATLKRLSRLYPQELTEHFIYLPTVSVDDLANESAMQGWLEKFQARLTAAEKSGLTYKASLREDRERHLWLPEVELVAHGLSSYVTFNRDFFASNDYRSVSLLGDQLNSLLEDGAYVQKGERKRPISAFKDGLDWLMAEGTKRHSIQRYKGLGEMNPEQLWETTMDPNVRRMLKVTIEDAIAADQIFNTLMGDAVEPRRDFIESNALAVSNLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSN10_KLULA
Sequence: MSDEEDYAEYMMSEEDMSSFEMDVDSDVEPDDAGLEQDQQVTGDDYDGSAGNSGDSMAAVEKQCESWYDTGKAFKNDDQFEEARKWFMKCHASPIWWFKSLKQIIKSDLSQGLRVNERLREMFELVSTKKEMIGEESYIYGSVKRLINRIVPDLNSHLLFTERLRQSSIDVSTLMERQRYLDILEKSVADMDQELRDLVTIRKIVYCVWIHVLRWEQIPKETLEDLHENVNLETYFILLQLHVRTFVDEDIVHLIELVKVVDEMGRFMTNSLSVSQIPTVTSVYHFARFLTLWKSTDHYNQSQMLSKCEGELTSCFQDLEAIGGTERDGLMLTRFSLMGIVFCHLLLNDKTKLVPFELEQIKVLEADELVVLLQELYQCWLDMDIYALEQCLLQLEDFYSPWYNVMIEKIIALCQSNKLWKRIAPTYSCIALQDLMAKLETGNTITMNRDQLLTLLMKSIAKDTADVYYKLDLVEDYVYFGEEYFVPLRSEELNIVNPLSQQMGSEIIGKDEWLCNVSNWHKPKVPKKLSAIEFMDYMKAARVTISQTNLAHHEPTVTSFLLKLSTITHAQLTQNSSSLASTN
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.  The CSN complex is involved in the regulation of the mating pheromone response (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 10.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FADB_VIBC1
Sequence: MIYQAETLQVKEVQDGIAELSFCSPKSVNKLDLATLESLDKALDALKAHQGLKGLMLTSDKDAFIVGADITEFLGLFAKTDAELDQWLQFANSIFNKLEDLPVPTISVLKGHTLGGGCECVLATDMRIGDKTTSIGLPETKLGIMPGFGGCVRLPRVIGADSAMEVITQGKACRADEALKIGLLDAVVDSDALYESALKTLTSAINEKLDWQARRKQKTSPLTLSKLESMMSFTMAKGLVAQKAGPHYPAPMTAVITIEEGARFARNEALDIERKHFVKLAKSEEAKSLVGLFLNDQYIKGLAKKSAKSASKDTQRAAVLGAGIMGGGIAYQSALKGVPVLMKDIAQPSLDLGMTEASKLLNKRLSRGRIDGFKMAGILASITPSLHYTGIEESDVIVEAVVENPKVKAAVLSEVESHVGEDTVITSNTSTIPINLLAKSLKRPENFCGMHFFNPVHRMPLVEIIRGEHTSDETINRVVAYAAKMGKSPIVVNDCPGFFVNRVLFPYFGGFSMLLRDGADFTKIDKIMERKFGWPMGPAYLLDVVGIDTAHHAQAVMAQGFPERMGKQGRDAIDALFEASKYGQKNGSGFYSYTIDRKGKPKKTFSEEILPVLADVCTDKQDFDDQTIIQRMMIPMINEVVLCLQEGIIATPQEADMTLVYGLGFPPFRGGVFRYLDSVGIAEFVAMAKQYSELGAMYQVPQMLIDMAAKGESFYGAQQQGSI
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: ATPF_OLTVI
Sequence: METYMDTLNQLSTICFGHGDGFGINTNILETNIINLSVVIGVVVSFGGDALRSLLDNRKETILANLQEADLRAKEAQEKLAAARLQLEQAQTKAQEIRQQGTITAEQEKQLCIKQAEADMARLEDVKQQTLRLQQQRAMSQVSQQVIALALQKVRQKLQDAANSAFHTSVNNSNIAFFTKYKV
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: LUXP_PHOPO
Sequence: MFKGIVQGVGIIKKISKNDDTQRHGITFPKDILDSVEKDTVMLVNGCSVTVVRITGDVVYFDIDQAINTTTFRKLEVGNKVNLEVRPGFGSLLGKGALTGNIKGVATVDNITEEEDLLKVYIKIPKDLIENISSEDHIGINGVSNSIEEVSNDIICINYPKNLSITTNLGTLETGSEVNVETLNVSNEW
What is the function of this protein?
Antenna protein that modulates the color of the bioluminescence emission of the luciferase.  In the presence of LumP, luciferase emission is shifted to higher energy values (shorter wavelength).
What are the official names of this protein?
Lumazine protein, LUMP.
Protein: RL24_HALHL
Sequence: MRKIRTGDEVIVIAGKDKGRRGRVSRVIPEKDRVIVDNVNMVKRHTRGNPMQGTTGGIIEKEAPIHISNVAIYNPETEKADRVGVRQEGDRKVRYFKSNQQLIDA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: YEBF_SALDC
Sequence: MNKRGALLSLLLLSASVSAFAASTESKSVKFPQCEGLDAAGIAASVKRDYQQNRIVRWADDQKKVGQADPVAWVNVQDVVGQNDKWTVPLTVRGKSADIHYQVIVDCKAGKAEYKPR
What are the official names of this protein?
Protein YebF.
What is the protein family that this protein belongs to?
Belongs to the YebF family.
What are the subcellular locations of this protein?
Secreted.
Protein: SLT11_ASPFU
Sequence: MPPPQIKQDLNRSGWESTDFPSVCENCLPDNPYVQMLKEDYGAECKICTRPFTIFRWKADRTARTKRTTICLTCARLKNCCQCCMLDLSFGLPIVVRDAALKMVAPGPESSINREYYAQEHEKEIQEGRGAVEAYEKTDEKARELLRRLANSEPYYRKPRQQLEGPSDDSTEAQPTDAPVVQSRYGNGPGPIRTSESRRGTPLPGRGRGNMRGGRAGRPFPGTAQIPPSPEDYLPPADPNIMSLFVTGVEDDLPEHTLRTFFTQFGQLRSLICSHRAHCAFINFATREGAEAAAQHCKGKAVIQGCPLRVRWGKPKPLDNMDREERMKNAREGRLTVQAQKDGESGQRAITAAGEPATEKPQSFVVAPPPGSGDVQYSSLSGD
What is the function of this protein?
Involved in pre-mRNA splicing.  Facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome.  Binds to RNA (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor slt11.
What is the protein family that this protein belongs to?
Belongs to the SLT11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GP_HAZVJ
Sequence: MEGSYWWLSLLALLAWGANGESTSPAETSPAPTTPNPPVVNPSLRRKIVNQRILSAMGMDSDPSNEALNGVCQSIHSNGCNANELKLRLADFFIDTNSSQCYDEILVKKPCSSLTPAHNSHWVPRGLDKSEVDKIFDTKLKLFFSQSRKVTCLSASALNPSQFVKHFQVKIQETSGPAKQSLRSLHCVNLVWSHSHKGEKEVVHVLQSAVPVKLKNCLAMLNFRQCYYNQQSEGPVVVPSYQHNGEKWVTGAYTMTVEVDKHADGPCEISTTCITEGSEIKPGVHSLRGFKTTLVIHGKRNTGRRLLSSSNARQECSSGTFLGEGGSAQVVGPKNDGPGDHITFCNGSVVTKIRLGQEHGCYTVRRIKTYRNCRPEEGSSACEVDDELKPCGAQKCMNVHLSVKGLVKTSRGSNVQVHSCDKDCLIQIPEGFGDIQIDCPGGTQHYLESNVLDVDCPMYNRLGGLMLYFCRMSHRPRTCLALFIWLGAGYGITCIAGYMVYYAILALSMLTRCLKRKYMVKGDFCLKCEQKCVTSLDQTLHDESCSYNICPYCGNRLPEEGLRRHVPSCPKRKQRLEEIDLYLDYLLVPCPLHFALSTAVKLGTLLKRLSWVTVFLCLFLTAIAPVQGQVTTSPVLPSNQSTECTLLPPPVFLIFSAVLMSKTLKRMGPVNKVGAAGHSARRTNSPKNLYKSKQIANTKSGPREPRRRVVVKALLILTASSALQSIHLAQAFDSGSLPEGAWEEEMQLVQGCNQECSLEEDECSCPDGQSMTRKLLFFKGLNSAASKMASSHRLLTSVSIDTPWGAIKVESTYKPRLASSNIQLAWNSIEEQGDKVILSGKSTSIIKLEEKTGMQWSLGSESAAEEKRLLVSILDYTQVYSSTFQYITGDRTVSEWPKATCTGDCPDRCGCSTSSCLYKSWPHSRNWRCNPTWCWGVGTGCTCCGVDILRPFNKYFVTKWTTEYVRTDVLVCVELTDQERHCDVVEAGSQFVIGPVRVVVSDPQNVQTKLPSEILTIQKLEGNQVVDIMHATSIVSAKNACKLQSCTHGSPGDMQILHTDNLIQHSHDGGLNLADLNPLVNSTWMSWEGCDLDYYCTTGSWPSCTYTGINSENTESFDNLLNTESNLCERFHFHSKRISASGSTLQMDLKGRPNSGGGELSVLVDVKGLELHSKKISLKGLSFKTLSCSGCYACSSGLSCTVEVRIERPDEFTVHLRSVSPDIAVAEGSIIARRMTGGPLSRLRAFAVRKVKKICFEIVEKSYCKDCKNEDTTKCIEVELQPPKDILLEHKGTIIKRQNETCVSGLQCWTESASSFVSGVGSFFRNYLGSITLGIVLTLLPVAVVLLFFCYGDKLFKLCSCFRCCRGLSRGKVRKELDEDELRNKLKKFSKEGELFGKEKKDARTIALLLSGKGKNYKELV
What is the function of this protein?
Glycoprotein C and glycoprotein N interact with each other and are present at the surface of the virion (By similarity).  The spikes at the surface of the virion are formed by an N-terminal extension of glycoprotein C (By similarity).  Glycoprotein N and glycoprotein C are able to attach the virion to host cell receptors (By similarity).  This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity).  Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion (By similarity).  Exposure to potassium is necessary for the conformational change leading to fusion (PubMed:29678879).
What are the official names of this protein?
Envelopment polyprotein, M polyprotein.
What is the protein family that this protein belongs to?
Belongs to the nairovirus envelope glycoprotein family.
Protein: KNDC1_HUMAN
Sequence: MQAMDPAAADLYEEDGKDLDFYDFEPLPTLPEDEENVSLADILSLRDRGLSEQEAWAVCLECSLSMRSVAHAAIFQSLCITPDTLAFNTSGNVCFMEQLSDDPEGAFVPPEFDVTGNTFEAHIYSLGATLKAALEYVAEPTLEPRLSQDLEALLSRMQAEDPGDRPDLESIIALCEEKLQLTSSCRVCRSLSAVGRRVLSIESFGALQDVSESSWRERPAPGNAGPRRPPGDPSTDPEVLPTPEGPESETSRGPRASPTKALLSTPVRNGESHSREGLAGLVLDAERTLGELDRDALRRSRLRKVQTFPRLLSDSPEATLCLPLTRGKSQLPISELFSPDPRKAFLDRKNGLSSFQAQPKCRLWPEQEPEHQLGRVPCAGRSTDRGPGVPGSPGQPETSHPSQGPAEAPADPRDASGEAQTPRDDERIPEGARQLESAAAEQWVSLQDLLSQLGRPFREYELWALCLACLRALQTRPEHPAYLCLDSVLVAEDGAVLFQPPPANGSYDSFFLAPELAEERLVTEKASVYCVAAVLWTAAKFSVPRNHKLALPRRLKTLLLDMARRSAPERPSAAEAIKVCGSYLLQRGMDSRKILAHLRASICQVYQEEETISLQNAFSVVELKPSVAPAPEPSPGFLPVNSDTGLVAVPGPVPGQHPCGEEATQLPAAFTSEATHFKPIVLAQNASVARDQPALAQEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQGRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVASGGLRPDALGPTTAHHGPRHPPKPPRSKATERPGQEPEGPGATPAGERDDQSPDSVPERPRPADRRLCLPCVDASPLPGRTACPSLQEATRLIQEEFAFDGYLDNGLEALIMGEYIFALKDLTFATFCGAISEKFCDLYWDEKLLQNLFKVVNGQASPSPSTAEEAGSQLEGSQSPRSPSSKRPSLHRLGKEKPAMARTSSRAPCSPTSVSDVDSDALSRGNFEVGFRPQRSVKAERAQQPEAGEDRRPAGGASDVEAVTRLARSKGVGPALSPGPAGFQSCSPGWCSAFYEADCFGADVHNYVKDLGRQQADGALPDAQSPELEQQLMMEKRNYRKTLKFYQKLLQKEKRNKGSDVKTMLSKLKGQLEEMKSRVQFLSLVKKYLQVMYAERWGLEPCTLPVIVNIAAAPCDTLDFSPLDESSSLIFYNVNKHPGGRQKARILQAGTPLGLMAYLYSSDAFLEGYVQQFLYTFRYFCTPHDFLHFLLDRINSTLTRAHQDPTSTFTKIYRRSLCVLQAWVEDCYAVDFPRNSGLLGKLEDFISSKILPLDGSAKHLLGLLEVGMDRRAEGNPRGTDLENPREAEEDARPFNALCKRLSEDGISRKSFPWRLPRGNGLVLPPHKERPYTIAAALPKPCFLEDFYGPCAKTSEKGPYFLTEYSTHQLFSQLTLLQQELFQKCHPVHFLNSRALGVMDKSTAIPKASSSESLSAKTCSLFLPNYVQDKYLLQLLRNADDVSTWVAAEIVTSHTSKLQVNLLSKFLLIAKSCYEQRNFATAMQILSGLEHLAVRQSPAWRILPAKIAEVMEELKAVEVFLKSDSLCLMEGRRFRAQPTLPSAHLLAMHIQQLETGGFTMTNGAHRWSKLRNIAKVVSQVHAFQENPYTFSPDPKLQSYLKQRIARFSGADISTLAADSRANFHQVSSEKHSRKIQDKLRRMKATFQ
What is the function of this protein?
RAS-Guanine nucleotide exchange factor (GEF) that controls the negative regulation of neuronal dendrite growth by mediating a signaling pathway linking RAS and MAP2 (By similarity).  May be involved in cellular senescence (PubMed:24788352).
What are the official names of this protein?
Kinase non-catalytic C-lobe domain-containing protein 1, KIND domain-containing protein 1, Cerebral protein 9, Protein very KIND, v-KIND, Ras-GEF domain-containing family member 2.
What are the subcellular locations of this protein?
Cell projection, dendrite. Perikaryon.
Protein: Y826_TREDE
Sequence: MAGKFEIYKDKSNKFRFRLKAGNGEVIAVGEAYESKAGCLSGIESVRKNAPDAAVVEV
What are the official names of this protein?
UPF0339 protein TDE_0826.
What is the protein family that this protein belongs to?
Belongs to the UPF0339 family.
Protein: TAU_HUMAN
Sequence: MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKYVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
What is the function of this protein?
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311).  The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270).  Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome.  The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
What are the official names of this protein?
Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Secreted. Note=Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components (PubMed:10747907). Can be secreted; the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum- Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059).
Protein: PCNA_METAR
Sequence: MFKAAINAEVFKDAIEAVSTLVDEAKFRITKDSISARAVDPANVAMVAFDLNAKAFDTFEATDGEIGIDLVRFMDILGMTARDDRLELNLNEETRKLEIRTGGLAYTLSLLDPGSIRKEPKVPALELPGKIVLNGAELKRAVKAAEKVSDHMALGVQDKTFYVEAEGDLDKVRLEIPESNLISLQATSNVRSLFSLDYLNDIVKSLGKAEQVTIDLGTDYPVKFTFSIASGNGTVIYLLAPRIESE
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: HM7X_CHICK
Sequence: GPKGKGKGGPAAEQPPPGSGAGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSNRSGEPVRNPKIVRAHPGARQSLRRAQPAPADRAGA
What are the official names of this protein?
Homeobox protein CHOX-7.
What are the subcellular locations of this protein?
Nucleus.
Protein: FDL14_ARATH
Sequence: MEQKFKTDSMNEDRISDLPDALLLQILSSLPTENAIATSVLSKRWRSLWTMLPKLKFDSNFNPVFDDDNIDPTMFSENVYKTLSLHKAPVLESLHLSFEGRTDCLHVGIWIATAFARGVRKLVLDSFYQEDQTVTLPSVLFSYNDSLEILKLKCAIDLDFPSRVCLKSLRKLYLDQVHFKDEESVCNLLCGCPSLQDLVVHRYSNADVATFTIASPSLQRLTIEDLRQEGGYGNGSYVINAPGLKYLNINGVIDIESCLIDKALELEEAKISNVSGITNENILESLTSAKRLILHLSPLEVKVPTGKIFDQLGCLELLTHEREWWNLLSIMLDSSPKLQILKLTDVYLHDNKTNPDERKWNPPKCAPECLLFHLETFLWIGYEWQRGDEKEVATYILENARRLKKATFSTKRIGREKLEDFEKRREMLNELAIVLWDSNSCHLVFEST
What are the official names of this protein?
F-box/FBD/LRR-repeat protein At2g04230.
Protein: ARGR_ERWT9
Sequence: MRNSSKQEDLIKAFKALLKEEKFSSQGEIVNALQEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTTSPLKNLVLDIDFNDALVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFITPARSFTVKQLHDAILVLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAZ_DESVM
Sequence: MLFRGRSHRSLDPKGRLMLPPDFRDILMSRAEGGKLVLTSFDDCVMGYPLPDWEDFERKFSTLKNPSRKMRDFRRLVIGSAELMELDGQGRVRISRSHMDYAGITKDVVLLGQGSRFEIWDQGRFDGIVTQDFDDVAAELADSGIELSL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: FPG_ACIC1
Sequence: MPELPEVETIRRGLARHLVGRRIGYAEVFHPRAVRRHSGGAADFTGRLIGRRIQAVLRRGKYLWFALDSDLALLAHLGMSGQFLLADAASPSPKHLRARFAFTDGDPELRFVDQRTFGGLTLAPLIADVPASISHIAPDILDVAFDEAEFHRRFTQRRTGVKRALLDQTLISGVGNIYADEALWRARLHYATPTVDISAATCRRLLAALRAVFRAALRAGGTSFDALYVNVNGQSGFFDRSLAVYGRAGQPCRRCGTAIVREPFMNRSSFRCPACQPVPRRPHW
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PG144_MONPV
Sequence: MSYLRYYNMLDDFSAGAGVLDKDLFTEEQQQSFMPKDGGMMQNDYGGIMNDYLGIFKNNDVRTLLGLILFVLALYSPPLISILMIFISSFLLPLTSLVITYCLVTQMYRGGNGNTVGMSIVCIVAAVIIMAINVFTNSQIFNIISYIILFILFFAFVMNIERQDYKRSINVPIPEQYTCNKPYTAGNKIDVDIPTFNSLNTDDY
What is the function of this protein?
Envelope protein which participates in virus morphogenesis.  Needed for an early step in viral crescent membrane formation by interacting with OPG125 scaffold protein.  Its interaction with OPG125 scaffold protein leads to the formation of rigid, crescent-shaped membranes that assemble around the cytoplasmic virus factory.  Acts as a membrane anchor for the protein OPG154.  OPG144-OPG154 virus envelope protein might be involved in fusion or attachment, and can further associate with OPG153.
What are the official names of this protein?
Virion membrane protein OPG144 precursor.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG144 family.
Protein: SYP_CORJK
Sequence: MITRMSQLFLRTLRDDPADAEVPSHKLLVRAGYIRRVAPGVYSWLPLGLRVLRNIEAVVREEMNAIGAQEISFPALLPREPYDTTGRWVEYGDALFRLKDRKNADYLLGPTHEEMFTSVVKSEYNSYKDFPVILYQVQTKYRDEERPRAGILRGREFIMKDSYSFNMDDEGLEESYQLHRKAYQNIFDRLGIKYAICSATSGAMGGSASEEFLAVAANGEDTFVRSTESDYAANVEAVVTQVPPAQPIEGQPEAKEYETPDSETIEALVEWANSEGITIDGRAVEAADTLKCIVIKVNDPTLDEEGKPRGESLAGVLVPGNREVDMKRLEASMEPAQVELADEADFKKNPFLVKGYVGPKGLAANGVRVLADPRVVDGTSWITGADAKNRHVVGLVAGRDFTPDGFVEAAEVLEGDPSPDGKGTLALARGIEIGHIFQLGRKYTEAFDVKILDESGKRSVPTMGSYGVGVSRLVGVIAEQMLDDSGLRWPASVAPFDVHVVIANKDAAAGEAAVELVETLSNDGLEVLFDDRPKVSPGVKFKDSELLGMPLVVVVGRGFADGKVELRNRLTGETYEVDYTDALPEAKRALRGEARP
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MODE_ECOLI
Sequence: MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGISYKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDVLSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKVAITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCEVLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC
What is the function of this protein?
Functions as an intracellular molybdate sensor.  The ModE-Mo complex acts as a repressor of the modABC operon, which is involved in the transport of molybdate (PubMed:8550508).  Binds modA promoter DNA in the absence of molybdate, however molybdate binding confers increased DNA affinity (PubMed:9210473, PubMed:9044285).  Binds the promoter of moaA activating its transcription; binding is not enhanced by molybdate (PubMed:9044285).  The protein dimer binds the consensus palindrome sequence 5'-TATAT-N7-TAYAT-3' and a variant 5'-TGTGT-N7-TGYGT-3' (PubMed:9210473, PubMed:9044285, PubMed:16205910).  Acts as a regulator of the expression of 67 genes, many of which encode molybdoenzymes, acts both directly and indirectly (PubMed:9466267, PubMed:10206709, PubMed:16205910).  ModE also binds tungstate (PubMed:9210473, PubMed:11259434).
What are the official names of this protein?
DNA-binding transcriptional dual regulator ModE.
What is the protein family that this protein belongs to?
Belongs to the ModE family.
What are the subcellular locations of this protein?
Cytoplasm.