PharMolix/UniProtQA huggingface dataset:
Protein: NL1A3_RAT
Sequence: MGESQSKQESNTRVAQHGSQQDVDPTFQTKRALERERSSPQVEQSFLGQLQSLLGWSSTSKDVPLSQLIREMDHESRRHSHQSKKKLDRSEHISEGTIPEIYEKRKETISHTQSMEQKYLFQNFTKLLLLQKCCPGGSEKLVRESWHPCVPEEGGHMIEIQDLFDPNLDTEKKPQLVIIEGAAGIGKSTLARQVKRAWDEGQLYRDRFQHVFFFSCRELAQCKQLSLAELIAQGQEVPTAPTRQILSRPEKLLFILDGIDEPAWVLEDQNPELCVHWSQAQPVHTLLGSLLGKSILPEASLMLTARTTALQKLVPSLGQPHRVEVLGFSEFERKDYFYKYFAKERNTIIDFNLIGSIPVLLTLCEVPWVCWLLCTCLEKQMQQGEVLSLTSQTTTALCLKYLSLTIPGQHLSTQLRTLCSLAAEGICQRRTLFSKSDLCKQGLAEDAIATFLKIGVLQRQPSSLSYSFAHLCLQEFFAAMSYILEDSEEAHGDMGNDRTVETLVERYGRQNLFEAPTVRFLLGLLNTREMREMENIFACKFPWETKLKLLQSIIGEPFCQPCHLGLFHCLYENQEEELLTETMLCFPLTASGPNHMEATVFQTNVKRLVIQTDMELMVVTFCITFSHVRSLRLKGKGQQEYKLTAPAMVLYRWTPISEASWKVLFSNLKCTRNLEELDLSGNPLSYSAVRSLCTALRQPGCRLKTLWLVDCGLTSRCCSFLASMLSAHSRLAELDLRLNDLGDNGVRQLCEGLRNPACNLSILRLDQASLSEQVITELRALETKNPKLFISSTWMSHMTMPTENTDGEESLTSSKQQQQQSGDKHMEPLGTDDDFWGPSGPVSTEVVDRERNLYRVRLPMAGSYHCPSTGLHFVVTRAVTIEIGFCAWSQFLHETPLQHSHMVAGPLFDIKAEHGAVTAVCLPHFVSLQEGKVDSSLFHVAHFQDHGMVLETPARVEPHFAVLENPSFSPMGVLLRMIPAVGHFIPITSITLIYYRLYLEDITFHLYLVPNDCTIRKAIDEEELKFQFVRINKPPPVDALYVGSRYIVSSSKEVEILPKELELCYRSPRESQLFSEIYVGNIGSGINLQLTDKKYMNLIWEALLKPGDLRPALPRMASAPKDAPALLHFVDQHREQLVARVTSVDPLLDKLHGLVLSEEDYETVRAEATNQDKMRKLFRGSRSWSWDCKDHFYQALKETHPHLIMDLLEKSGGVSVRL
What is the function of this protein?
Constitutes the active part of the Nlrp1a inflammasome.  In absence of pathogens and other damage-associated signals, interacts with the N-terminal part of Nlrp1a (NACHT, LRR and PYD domains-containing protein 1a, N-terminus), preventing activation of the Nlrp1a inflammasome.  In response to pathogen-associated signals, the N-terminal part of Nlrp1a is degraded by the proteasome, releasing this form, which polymerizes to form the Nlrp1a inflammasome complex: the Nlrp1a inflammasome complex then directly recruits pro-caspase-1 (proCASP1) and promotes caspase-1 (CASP1) activation, leading to gasdermin-D (GSDMD) cleavage and subsequent pyroptosis.
What are the official names of this protein?
NACHT, LRR and PYD domains-containing protein 1a allele 3.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Nucleus. SUBCELLULAR LOCATION: [NACHT, LRR and PYD domains-containing protein 1a, C-terminus]: Inflammasome.
Protein: ATPA_SELUN
Sequence: MVNIRPDETSSIILGQTAQYDQEVGVFSTGTVLQVGDGIARIHGPDGVTAGELVESEDGTVGIALNSEPDNAGAVSMGDGSTIQEGSSVKATGKIAQIPVSDAYLGRVANAPAQPTDGKGRIAASEPRLTESPAPGIISRRSVYEPMQTGLIATDPMIPTGRGQRELIIGDRQTGKTAVAIDTTPNQRGQNVICVYVAIGQKASPAAQVVSTFEERGAMEYTVAVAETANPPATSQYLAPYTGAALAEYFMYRKRHTLIIYDDPSKQAQAYRQMSLLPRRPPGREAHPGDVPHLHPRPPERAAKLSSQPGEGSTTASPTVETQAGDVSAYIPTNVTSTTDGQIFLSADLSNAGVRPATNVGISASRVGPAAQIKATKQVAGKSKSELAQFAEPEASAQFASDPDKATRNQSARGQRSRELLKQSQPAPLPVEEQVATTHAGASGFSDVSEIGQVQGSPAQSREYLVTNKPEPAEIVRPTKTFTERAETILKEAIKEHTESFSLKKQI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, chloroplastic, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: VP5_BTV1A
Sequence: MGKVIRSLSRFGKKVGNALTSNTAKKIYSTIGKAAERFAESEIGSAAIDGLVQGSVHSILTGESYGEYVKQAVLLNVLGSGEEIPDPLSQGETEIQAKLRELEDEQRNELVRLKYNDKIKEKFGEELEEVYEFMNGAAKAEVEDEKQFDILNKAVTSYNKILTEEDLQMRRLANALQKEIGERTHAETVMVKEYRNKIDALKNAIEIERDGMQEEAIQEIAGMTRGVLEAASEEVPLIGAGMATAVATGRAIEGAYKLKKVINALSGIDLTHLRTPKIEPSVVSTILEYRTRAIPDSALAVSVLSKNRAIQENHKELIHIKDEILPRFKKAMDEEKEICGIEDKTIHPKVMMRFKIPRAQQPQIHVYSAPWDSDDVFFFHCISHHHANESFFLGFDLSIDLVHYEDLTAHWHALGAAQMAMGRTLSEAYKEFLNMAISNAYGTQMHTRRLVRSKMVHPIYLGSLHYDISFLDLRGNAQRIVYDDELQMHILRGPIHFQRRAILGALKFGCKVLGDRLDVPLFLRNA
What is the function of this protein?
VP5 protein is one of the two proteins (with VP2) which constitute the virus particle outer capsid.  Acts as a membrane permeabilization protein that mediates release of viral particles from endosomal compartments into the cytoplasm.  Permeabilization activity is probably negatively regulated by VP2 and is triggered by endosomal degradation of VP2 and exposure to low pH (By similarity).
What are the official names of this protein?
Outer capsid protein VP5.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP5 family.
What are the subcellular locations of this protein?
Virion.
Protein: RL5_XYLFM
Sequence: MTRLENMYKKEVVPALIKRFGYSNPMAVPRLVKITLNMGVGEAATNKKVLENAVADMAKVSGQKPIVTKSRISVASFKIRNGWPIGCKTTLRRSKMYEFLDRLINISLPCVRDFRGIPPRSFDGRGNFNMGVKEQVVFPEIDFDAVDAIRGMDIAITTTANSDAEAKALLDAFNFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: TIGD3_MOUSE
Sequence: MELNTKKKLHALSLAEKIQVLELLDESKMSQSEVARRFQVSQPQISRICKNKEKLLADWCSGTANHERKRKRESKYSGIDEALLCWYHIARAKAWDVTGPMLLHKAKELADIMGQDFVPSIGWLVRWKRRNNVGFGTRQVLVPLFPPEAPPAVLPSQAQPPLSLKDFSPEDVFGCAEVPLLYRAVPGRVFECDRLQVLLCANSRGTEKRRVFVGGLQAAPRCFFGVSSEALPTSYHPDLAIPWSEWLAQFDQDMGQQGRQVALLLASGVVEEWASLPGLHHVRLLPLSASSTTPSLPGSVILAFKAHYRHRLLSKLAAMQSGKEGTSLAEARASITVLDALHMVAAAWAKVPRQLILSSFVQEGLAPGKTPLSLDKDTEMSPVPSGLSQEEFSHFVDLEDEDPGPRVCKEETGTEDSGREEDGFEPLPTKADALQALCTLRRWLECNSASPELFEKFYDCEVEVEQLCCL
What are the official names of this protein?
Tigger transposable element-derived protein 3.
What is the protein family that this protein belongs to?
Belongs to the tigger transposable element derived protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EF1A_PYRCJ
Sequence: MPSIVLPPKPTALQKPHINLAVVGHVDNGKSTLVGRLLYETGYVDEKAFKEIEEMAKKMGKEDFAFAWILDRFKEERERGVTIEATHVGFETQKLFITIIDLPGHRDFVKNMIVGASQADAALFVISARPGEFETAIGPQGQGREHLFLIRTLGIQQLVVAVNKMDAVNYDQKRYEQVKAEVSKLLKLLGYDPSKIHFVPVSAIKGDNVRTKSPNTPWYQGPTLLEVLDTFQPPPRPTDKPLRMPIQDVFSITGAGTVVVGRVETGVLKVGDKVVIVPPAKVGDVRSIETHHMKLEQAQPGDNVGVNVRGINKEDVKRGDVLGKVDNIPTVAEEIVARIVVLWHPTAIGPGYAPVMHIHTATVPVQIVELVSKLDPRTGQAVEQKPQFIKQGDVAIVKIKPLKPVVAEKFSDFPPLGRFALRDMGRTIAAGQILEVKPAQVQIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NST1_CANAL
Sequence: MSDIMDRVDNSTRKFKLGDNIHFEISSSANTQGNSHQIPRKQSQSTNSNHQEQSQQARNQSSQSNTNTTSRKKRKKHKKKSKISTVQAHLNNPEDDYPTSRVIKQAPNGDVIVESLEDEDENHHHHEYEEHEDSCEYHPSSKSNTRKNSSVNESTHNKIWDSASIEEQQRLKEFWESLDESKKLDLVKIDKDSIMRMFKNETRHHLQQQLSSSVSSQPQQQQSQQNVSTSSNNGSSSGINNNSNNNNGNNTNSCACKYCGRRNSIIEEELESIYDNHFDDIIDFIHEVRDINDLNALPGLLFGGFHMLEEERRLQKRQQKYKEKWNHSHHSTSVSPQPESQDNKQLKKSQDQNEMKAISIEDEMDKFKSHLAKMSISNSQSNPNQLSEIHLQLKSEDGNLTGTTESQLFNKLLDPKLFEALENMDLDKMKEMSKMDPKNLNNVNILEKATSLREIVRDLNNADRSSLQKGISHVSNMGKFFSNLATLNNAQNLPEIVASGGLDDQLSKGLSSFAEDLLKNDGNSFIGMMEALSESRTAREELLKETVISQNPQEQKSVSIGQSDQSGDVWVDDDDENNRVDVEIHACDNPHHHHHHHQHSNKQHDHHHCHNHRHRHRRRFEELDDEHDQENEDEELEDDEEDYYDEYDDDEEEDEEEDEDDDDIEEEGASDTESEISEEEKMQEIRRLFLIQVIKLFQERLKNAYKEKLSQDRTQKLIEELEAEENAKKERELKKLKQKEKAKEKKRLQQLAKEEERKRKEEELKAKEEEQRLQKEKLKAEQKKRKEEARLKKEEEKKKKIEEQKRKEEEHRKKVEAQQKREAEAKKLKEERRRKAEEERKQKEEEKKQKELLKKQKEEEKRQKELLRKQREEEKEKEAARLEEERTKLMVNDDDELARQIEVEKSKLSAAVANNPLLNHLYQPSPGSAPTTPSTANLPALSPLQSASAKLMSQQFEQQHLQQVSQEKLPQTSNIQSPNQQPHPSISSFQFSSEYNSNASVFHNNSSLLSNPSIMNSPRTTSTNLLNGNSPIVPNVTTNISLGATNTSNLSPWSSKSRLNSLSNSTQPFIGGNQFTQTNTASFNGVGNAVQQSGNFSPFNAFSDPLVSDAFKAAGPAGMNSNIWLNSSNVGNNSGNQSGISAPTTTSTNTSSRNNSIWGNTNPNKVTEPSLLNNNNNNNNGLISVESSGLWNSNGGNNQPARSSSVTGISSNLSTINPISSMDIELIQSTTFNCFQILQNSGQLEFGVAPLMKLFQNVKTILNKPSLTINQFLNCCTINSNVYIFSLKYDDFGNVTHVEVAYKNVPRTSPPPPPGNIVQNQHQVSSPSFAAATASSSSLATSNVPLGFINSGGSPTGLFNDININHGGTSFLPPIGESSTNDAGSSNVGNSGFGRRLWN
What is the function of this protein?
May act as a negative regulator of salt tolerance.
What are the official names of this protein?
Stress response protein NST1.
What is the protein family that this protein belongs to?
Belongs to the NST1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_VIBCH
Sequence: MWVGIVSLFPEMFRSVTDFGVTGQAVKKGLLSVEAWNPRDFAHDKRRTVDDKPYGGGPGMLMMVQPLRDAIHAAKQASPGKTKVIYLSPQGRKLDQQGVEELAQNQNLILICGRYEGVDERIIESEVDEEWSIGDFVMTGGELPAMTLIDSVSRFIPGVLGDFASAEEDSFANGLLDCPHYTRPEVLDGKEVPAVLKSGNHEDIRRWRLKQSLGRTWLRRPELLENLALTDEQEQLLTEYIKETRHQ
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YA00_METTH
Sequence: MWNDLAVYIIRCSGPGTRVVEVGAGRFLYVSDYIRKHSKVDLVLTDIKPSHGGIVRDDITSPRMEIYRGAALIYSIRPPAEIHSSLMRVADAVGARLIIKPLTGEDIVTERKMKLVNYGRTYFYEYIAEVRSR
What are the official names of this protein?
UPF0146 protein MTH_1000.
What is the protein family that this protein belongs to?
Belongs to the UPF0146 family.
Protein: 5HT5A_RAT
Sequence: MDLPINLTSFSLSTPSTLEPNRSLDTEALRTSQSFLSAFRVLVLTLLGFLAAATFTWNLLVLATILRVRTFHRVPHNLVASMAISDVLVAVLVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHLEYTLRARKRVSNVMILLTWALSAVISLAPLLFGWGETYSELSEECQVSREPSYTVFSTVGAFYLPLCVVLFVYWKIYKAAKFRMGSRKTNSVSPIPEAVEVKDASQHPQMVFTVRHATVTFQTEGDTWREQKEQRAALMVGILIGVFVLCWFPFFVTELISPLCSWDIPALWKSIFLWLGYSNSFFNPLIYTAFNRSYSSAFKVFFSKQQ
What is the function of this protein?
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen.  The activity of this receptor is mediated by G proteins.
What are the official names of this protein?
5-hydroxytryptamine receptor 5A, 5-HT-5A, 5-HT5A, REC17, Serotonin receptor 5A.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RECF_SALAR
Sequence: MSLSRLLIKDFRNIENADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETSIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEAGFFTAWSNLKRLLKQRNAALRQVSRYEQLRPWDKELIPLAEQISTWRAEYSSAIAQDMADTCQQFLPEFSLTFSFQRGWEKETDYADVLERSFERDRILTYTAHGPHKADFRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDARRGLLASRLKATQSQVFVSAISAEHVLDMSDKNSKMFSVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_ECOHS
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: HASC1_STRP1
Sequence: MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKTHASTIAVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFGILERQTPGAGNEVQLTDAIDTLNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVPTHSK
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase 1, Alpha-D-glucosyl-1-phosphate uridylyltransferase 1, UDP-glucose pyrophosphorylase 1, UDPGP 1, Uridine diphosphoglucose pyrophosphorylase 1.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 2 family.
Protein: MNME_NITWN
Sequence: MHPREQTIFALSSGRPPSAIAVVRASGSQAGTALRKLAGAIPAARTAKRVLLRDSVGEAIDDAVILWFPAPASATGEDIAEFHVHGSRAVVNALIAALSSIDDARAAEPGEFTRRAFENGKIDLTEAEGLDDLIHADTDRQRRQALRQLQGLLGDRARGWRKELIDASALIEAGIDFADEEDVPEDLARPALEKIAQLRREIEQTLAASARGERLRDGLTVAIAGPPNAGKSTLLNRLARREAAIVSPHAGTTRDIIEVYLDLDGYPVTLIDTAGIRETDDPVEQEGVRRARDRVAKADLVLWLSDDHGGEPDQTIRSGETSLWLIRNKIDLAGPENDGAKPGRFETKAGQSAPPWRFRISASRGDGVDDLVSALTAFAEKLLGSSEAGVITRLRHRNILRDAVASLAKAETLAGRGDELVAEELRIAIHLMGRLLGRVDIDDILDSLFKEFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_STRP8
Sequence: MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQSYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNATYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTITVRGEAYMSRQSFKAINEARQENGETEFANPRNAAAGTLRQLDTSVVAKRQLATFLYQEASPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVVIKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIPKLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFLAGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGSKVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAGVNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVIAGSDAGSKLEKAKSLGIRIEDEDWLRKL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: NP_CIMLE
Sequence: MKLLLSAGAALAFVLGLCAAGSPPAQLSVHTVSWNSGHERAPTNLEELLGLNSGETPDVIAVAVQGFGFQTDKPQQGPACVKNFQSLLTSKGYTKLKNTITETMGLTVYCLEKHLDQNTLKNETIIVTVDDQKKSGGIVTSFTIYNKRFSFTTSRMSDEDVTSTNTKYAYDTRLDYSKKDDPSDFLFWIGDLNVRVETNATHAKSLVDQNNIDGLMAFDQLKKAKEQKLFDGWTEPQVTFKPTYKFKPNTDEYDLSATPSWTDRALYKSGTGKTIQPLSYNSLTNYKQTEHRPVLAKFRVTL
What is the function of this protein?
Heme-based protein that delivers nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation (Probable).  In place of heme, the heme-binding cysteine can also reversibly bind NO when it is present in high concentrations (PubMed:15637157).
What are the official names of this protein?
Nitrophorin Cim l NP, NP, Salivary nitrophorin, cNP.
What are the subcellular locations of this protein?
Secreted.
Protein: CCMA_TATCI
Sequence: MLEAKELTCARDERVLFSQLSFTVGAGNIVQIEGPNGAGKTSLLRILAGLSRPESGEILWNQTAVGRQRDIWQREMLYLGHLPGVKGVLSPLENLRFFHPDCSDEQIFDALDEVDLTGYEDAIVAQLSAGQQRRVALARLWLSQARLWILDEPLTAIDKAGVEKIMSQFASHAGRGGSVILTTHQDLPDQQDVVRKIRLTAEGRDECW
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UREG_OPITP
Sequence: MRTTTRRAPRVGIGGPVGSGKTMLCLKLCQRLRERLSMAVVTNDIYCSEDAQFLIRQSALPAARIAGVETGGCPHTAIRDDTTMNEQACRALEATFPELDLLLVESGGDNLTATFSPELVDAFIYVIDVAEGDKIPRKGGPAIRFSDLLIINKVDLAPLVGADLEVMARDATAQRGGRPFLLCDLKREHNLDAVIGWLEREVLFARTAAPVG
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CONG_BOVIN
Sequence: MLLLPLSVLLLLTQPWRSLGAEMTTFSQKILANACTLVMCSPLESGLPGHDGQDGRECPHGEKGDPGSPGPAGRAGRPGWVGPIGPKGDNGFVGEPGPKGDTGPRGPPGMPGPAGREGPSGKQGSMGPPGTPGPKGETGPKGGVGAPGIQGFPGPSGLKGEKGAPGETGAPGRAGVTGPSGAIGPQGPSGARGPPGLKGDRGDPGETGAKGESGLAEVNALKQRVTILDGHLRRFQNAFSQYKKAVLFPDGQAVGEKIFKTAGAVKSYSDAEQLCREAKGQLASPRSSAENEAVTQMVRAQEKNAYLSMNDISTEGRFTYPTGEILVYSNWADGEPNNSDEGQPENCVEIFPDGKWNDVPCSKQLLVICEF
What is the function of this protein?
Calcium-dependent lectin-like protein which binds to a yeast cell wall extract and immune complexes through the complement component (C3bi).  It is capable of binding non-reducing terminal N-acetylglucosamine, mannose, and fucose residues.
What are the official names of this protein?
Conglutinin.
What is the protein family that this protein belongs to?
Belongs to the SFTPD family.
Protein: PRTA_LISMN
Sequence: MKSKLICIIMVIAFQAHFNMAVKADSVGEERLRNNIQAKRNPADLKTLPDSCEAKDFYKNFKILDMTKDKLGVTHYTLALSSDGYLTDNDEIKVHVTPDNKITFINGDLQQGQLRITNQIKITEKNAIEKAFEAIGQSEAHVKSYIGNPVKEKEIIINSRTKRLVYNIKLIFAEPEVASWIIQVDAETGAILKKQNMLSEVERADTHKDFQALGKGANRLLQRPLHVMKINDLFYLVDRTHKGLIRTFDLNHKTDASFGKVVSNKTNMFTDPEFSSAVDAHFYASEVYDYYKNVHQLESLDGKGGEIDSFVHYGLNCNNAFWDGREILYGDGDKKNFKPFSCAKTIVGHELTHAVIQYSAGLEYEGQSGALNESFADVFGYFIAPNHWLIGEDVCVRGLRDGRIRSIKDPDKYNQAAHMKDYESLPITEEGDWGGVHFNSGIPNKAAYNTITKLGKEKTEQLYFRALKYYLTKKAQFTDAKKALQQAAKDLYGEDASKKVAEAWEAVGVN
What is the function of this protein?
Probably linked to the pathogenesis of listerial infection.
What are the official names of this protein?
Zinc metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: 018L_FRG3G
Sequence: MQNSKTDMCAALWAVTGLVLNVAVRFALEPFKESMGQGWHTAARVAVNGAIVLALADRLSDSPVTMTLFVMALSASPE
What are the official names of this protein?
Uncharacterized protein 018L.
Protein: HBEAG_HBVC7
Sequence: MQLFHLCLIISCSCPTVQASKLCLGWLWGMDIDPYKEFGASVEVLSFLPSDFFPSNRDLLDTASALDREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: UVRB_NEIGO
Sequence: MEVIRYPNSPFKLHQPFPPAGDQPTAIAGLLEGLSDGLAYQTLLGVTGSGKTYTMANVIAQSGRPAIIMAHNKTLAAQLYAEMREFFPENAVEYFVSYYDYYQPEAYVPSRDLFIEKDSAINEHIEQMRLSATKNLMTRDDVIIVATVSAIYGIGDPTEYQQMVLSVKEGDTIEQRDIIATLVSMQYERGDLDFKRGSFRVRGDVIDVYPAESSENALRISLFDDEIDRLDMFDPLSGSLHQRVGRYTVFPSSHYVTPRDTVLRACESIKEELRERIEFFAREQRPVEQQRIEQRTRFDLEMLYEMGFCKGIENYSRHFSGKKEGEPPPTLMDYLPDNAIMFIDESHVTVTQIGGMYKGDASRKQNLVDYGFRLPSARDNRPLKFHEFEKVMPQTVFVSATPAKYEEEHAGQVVEQVVRPTGLVDPQIIIRPVATQVDDLMSEINDRIQKGERVLVTTLTKRMAEQLTDYYSELGIKVRYLHSDIDTVERVEIIRDLRLGLFDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSHRSLIQTIGRAARNVNGVAILYADKITDSMKAAVDETERRREKQIKFNEEHGIVPQQIKKQVKDIIDGVYHEEDSGKGRRQGKNKVKVGEIHNEEDAIKEIAKLEKAMQQAARDLQFEEAAVLRDRIRNIKENLLFGAE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGJ_ECOL5
Sequence: MSRRYSLATITLVILFCGRPHCRKISVRQYYQKRVIFYPTTLQRTAFKKYLFLIRDIIISS
What are the official names of this protein?
Uncharacterized protein YmgJ.
Protein: INH8_TABYA
Sequence: MTSILVSRFKISALTLQYATSDSVNFCRIPCRGCDEKFLQCWLVASFHCGKGGPQFQKAKRVFLVRYTGGGIIVLRDSWGYRPFPMKGNVGARCVPEGLKSSPHTRGFRCLAASLECYSAKSFLGPLLCSPQKRGPMQKHNIRGDTLGKSPPCGPKGNFKGLPLVIFDGVPGVGGGLWPGKLGGKTPLFFSSNCFSGKESNPPVYKTGNLCGEKSPKKEETFKNFFFFPDPFNPNEQNFSSFLN
What is the function of this protein?
Inhibits platelet aggregation induced by all agonists tested (ADP, arachidonic acid, the thromboxane A2 analog U46619, thrombin, and snake venom snaclecs (TMVA that activates platelet through GPIB, and stejnulxin that specifically acts through GPVI (GP6))) (By similarity).  May act by competing with fibrinogen for binding to glycoprotein IIb/IIIa (ITGA2B/ITGB3) (By similarity).
What are the official names of this protein?
Tabinhibitin 8.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
What are the subcellular locations of this protein?
Secreted.