PharMolix/UniProtQA huggingface dataset:
Protein: PSBN_PROMA
Sequence: METSSPALSIAITILIVLLGLTAFGVYTAFGPPNRALDDPWDDHDD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ARFU_ARATH
Sequence: MESGNIVNAQPKLSGIIDGSKSYMYEQLWKLCAGPLCDIPKLGENVYYFPQGNIELVQASTREELNELQPICDLPSKLQCRVIAIHLKVENNSDEIYAEITLMPDTTQVVIPTQSENRFRPLVNSFTKVLTASDTSAYGGFSVPKKHAIECLPPLDMSQPLPAQEILAIDLHDNQWRFRHNYRGTPQRHSLTTGWNEFITSKKLVKGDVIVFVRGETGELRVGIRRARHQQGNIPSSIVSIDCMRHGVIASAKHAFDNQCIFIVVYKPRSSQFIVSYDKFLDAVNNKFNVGSRFTMRFEGDDFSERRYFGTIIGVSDFSPHWKCSEWRSLEVQWDEFASFSRPNKVSPWEIEHLVPALNVPRSSLLKNKRLREVNEFGSSSSHLLPPILTQGQEIGQLSVASPMNISLRYRDTTEAAMNPSRLLMSYPVQPMPKLNYNNQMVTQIEENITTKAGTNFRLFGVTLDTPPMIKDPIKQIGSDISKLTERKKFGQSQTLRSPIEIQSKQFSSSRTCTKVQMQGVTIGRAVDLSVLNGYDQLILELEKLFDIKGQLQTRNQWKIAFTDSDGYEMLVGDDPWPEFCKMVKKILIYSKEEVKNLKSSKSLSS
What is the function of this protein?
Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs).  Could act as transcriptional activator or repressor.  Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression.
What are the official names of this protein?
Putative auxin response factor 21.
What is the protein family that this protein belongs to?
Belongs to the ARF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MMP2_HUMAN
Sequence: MEALMARGALTGPLRALCLLGCLLSHAAAAPSPIIKFPGDVAPKTDKELAVQYLNTFYGCPKESCNLFVLKDTLKKMQKFFGLPQTGDLDQNTIETMRKPRCGNPDVANYNFFPRKPKWDKNQITYRIIGYTPDLDPETVDDAFARAFQVWSDVTPLRFSRIHDGEADIMINFGRWEHGDGYPFDGKDGLLAHAFAPGTGVGGDSHFDDDELWTLGEGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPHEALFTMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPETAMSTVGGNSEGAPCVFPFTFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHEFGHAMGLEHSQDPGALMAPIYTYTKNFRLSQDDIKGIQELYGASPDIDLGTGPTPTLGPVTPEICKQDIVFDGIAQIRGEIFFFKDRFIWRTVTPRDKPMGPLLVATFWPELPEKIDAVYEAPQEEKAVFFAGNEYWIYSASTLERGYPKPLTSLGLPPDVQRVDAAFNWSKNKKTYIFAGDKFWRYNEVKKKMDPGFPKLIADAWNAIPDNLDAVVDLQGGGHSYFFKGAYYLKLENQSLKSVKFGSIKSDWLGC
What is the function of this protein?
Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.
What are the official names of this protein?
72 kDa type IV collagenase, 72 kDa gelatinase, Gelatinase A, Matrix metalloproteinase-2, MMP-2, TBE-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
[Isoform 1]: Secreted, extracellular space, extracellular matrix. Membrane. Nucleus. Note=Colocalizes with integrin alphaV/beta3 at the membrane surface in angiogenic blood vessels and melanomas. Found in mitochondria, along microfibrils, and in nuclei of cardiomyocytes. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Mitochondrion.
Protein: FADR_ECOUT
Sequence: MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPIYGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
What is the function of this protein?
Multifunctional regulator of fatty acid metabolism.
What are the official names of this protein?
Fatty acid metabolism regulator protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_GEOUR
Sequence: MKQFAFPKYERLLKRSEFVQFTNARQRIHTAHFILLWTHTEDSTLKIGITVSRKVGNSVIRNRVKRLVREFYRLNKSRFVMAHYNIIAKKGAEQLDFQRLSRELANVLERLHK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CARDB_CYNCA
Sequence: MGTPIKASLLALFLFFLLSPTAFSVSNGGLLRVGLKKRKVDRLDQLRAHGVHMLGNARKDFGFRRTLSDSGSGIVALTNDRDTAYYGEIGIGTPPQNFAVIFDTGSSDLWVPSTKCDTSLACVIHPRYDSGDSSTYKGNGTTASIQYGTGAIVGFYSQDSVEVGDLVVEHQDFIETTEEDDTVFLKSEFDGILGLGFQEISAGKAVPVWYNMVNQGLVEEAVFSFWLNRNVDEEEGGELVFGGVDPNHFRGNHTYVPVTRKGYWQFEMGDVLIGDKSSGFCAGGCAAIADSGTSFFAGPTAIITQINQAIGAKGVLNQQCKTLVGQYGKNMIQMLTSEVQPDKICSHMKLCTFDGAHDVRSMIESVVDKNNDKSSGGEICTFCEMALVRMQNEIKRNETEDNIINHVNEVCDQLPTSSAESIVDCNGISSMPNIAFTIGSKLFEVTPEQYIYKVGEGEAATCISGFTALDIMSPQGPIWILGDMFMGPYHTVFDYGKLRVGFAEAV
What is the function of this protein?
Aspartic protease.  Cleaves alpha-lactalbumin but not beta-lactoglobulin.
What are the official names of this protein?
Procardosin-B.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Microsome membrane. Protein storage vacuole. Secreted, cell wall. Secreted, extracellular space, extracellular matrix. Note=Procardosin-B is associated with the microsomal membranes, the mature form is secreted.
Protein: NAGK_PECCP
Sequence: MYYGFDMGGTKIELGVFDAELNKVWQKRVLTPRTHYDELLTTLVDLVHEADAQVGVQGKVGIGIPGIQTGDNDALFTANLPAAMGKPLRTDLSQRLQRDVRINNDANCFVLSEAWDAEFRSYPVVLGLILGTGLGGGLVINGRPVDGRNGIAGEFGHLRLPSDALDIIGVDIPRVKCGCGQSGCIENYISGRGFEWLYEHMYGEALPAVTIIRHYRGGEEKAREFVDRFMDLLAACLGNLLTLFDPHLLVLGGGLSNFDEIYQILPTRLPSRLLPIAKLPRIEKARHGDAGGVRGAALLHLMDN
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: RL6_METM7
Sequence: MPVAALIREEIEIPENVNVEVNGSTVAVKSGAKELKRDLLYPGIEISTEDGKVVIECTFPRKAQTAIVGTYRSHIQNMITGVTDGFEYKLVIRYAHFPMKVSAKGNTVTIDNFLGEKYTRTAKIMDGVTVKVSGEEVIVSGANKEFVGQTAANIEQATKVKGRDTRIFQDGIYIVEKAGKVL
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: METE_STAA2
Sequence: MTTIKTSNLGFPRLGRTREWKKAIESYWAKKISKEELDQTLTDLHKENLLLQKYYHLDSIPVGDFSLYDHILDTSLLFNIIPERFQGRTIDDDLLFDIARGNKDHVASALIKWFNTNYHYIVPEWDNVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPITFVKLSKGGHQTFEEKVKTLLPLYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITREAYDYFEKAGVAKKLVIQTYFERAHLKFLSSLPVGGLGLDFVHDNGYNLKQIEAGDFDKSKTLYAGIIDGRNVWASDIEAKKVLIDKLLAHTNELVIQPSSSLLHVPVSLDDETLDTSVGEGLSFATEKLDELDALRRLLNQNDSVKYDKLKARYERFQNQSFKNLDYDFESVRTSRQSPFAQRIEQQQKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFLKNEIARWIKIQEDIGLDVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKPPIIYGDVKWTAPLTVDETVYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQIALAINEEVLALEAAGIKVIQVDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDETQIHTHMCYSQFGQIIHAIHDLDADVISIETSRSHGDLIKDFEDINYDLGIGLGVYDIHSPRIPTKEEITTAINRSLQQIDRSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKRQE
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: PA2A3_TROCA
Sequence: MYPAHLLVLLAVCVSLLGAASIPARPLNLYQFGNMIQCANHGRRPTRHYMDYGCYCGKGGSGTPVDELDRCCQIHDDCYGEAEKLPACNYMMSGPYYNTYSYECNDGELTCKDNNDECKAFICNCDRTAAICFARTPYNDANWNINTKTRC
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Acidic phospholipase A2 3, svPLA2, Phosphatidylcholine 2-acylhydrolase 3, PLA-3.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HME1_CHICK
Sequence: MEEPPEGHGHHRDAAPPGPANGGGGGGGGSDGDSAPVSPSPAPASPAAPCPLPLPRRRPPPPPPPRTTNFFIDNILRPDFGCKKEPPAATGAATGAGGGGGGGGREQRDGAQSAGRENVNPLLARPPHAPSSALLCPDSNCAPDGSAPAGTAAKANPGTAAGAAGAAGAAKAQGDGGETPAAKYGEHGSPAILLMGSNNGGAVLKPDSQQPLVWPAWVYCTRYSDRPSSPRTRKLKKKKTEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQSLAQELSLNESRVKIWFQNKRAKIKKATGIKNGLALHLMAQGLYNHSTTTVQDKEESE
What is the function of this protein?
Required for proper formation of the apical ectodermal ridge and correct dorsal-ventral patterning in the limb.
What are the official names of this protein?
Homeobox protein engrailed-1, Gg-En-1, Homeobox protein en-1.
What is the protein family that this protein belongs to?
Belongs to the engrailed homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: B3GA1_PANTR
Sequence: MPKRRDILAIVLIVLPWTLLITVWHQSTLAPLLAVHKDEGSDPRRETPPGADPREYCMSDRDIVEVVRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTARLLRDTGLNYTHLHVETPRNYKLRGDARDPRIPRGTMQRNLALRWLRETFPRNSSQPGVVYFADDDNPYSLELFQKVTRRVSVWPVAFVGGLRYEAPRVNGAGKVVGWKTVFDPHRPFAIDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPSVEI
What is the function of this protein?
Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins.  Can also play a role in glycosaminoglycan biosynthesis.  Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule.  Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin.  Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
What are the official names of this protein?
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 43 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted.
Protein: YPDB_ECOLI
Sequence: MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKPYQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEAHEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYILRLKDLDFEVPVSRSKVKEFRQLMHL
What is the function of this protein?
Member of the two-component regulatory system YpdA/YpdB, which is part of a nutrient-sensing regulatory network composed of YpdA/YpdB, the high-affinity pyruvate signaling system BtsS/BtsR and their respective target proteins, YhjX and BtsT.  YpdB regulates expression of yhjX by binding to its promoter region.  Activation of the YpdA/YpdB signaling cascade also promotes BtsS/BtsR-mediated btsT expression.
What are the official names of this protein?
Transcriptional regulatory protein YpdB.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRP5_BOVIN
Sequence: MAAMEESFPRGGTRKTHKSEKAFQQSVEQDNLFDISTEEESTKRKKIQKGPAKTKKLKVETRQSSKFVREKFEILNVESLCEGMRILGCVKEVNELELAISLPNGLQGYVQVTEICDAYTEKLNEQVAQEEPLQDLVGLPELFSPGMLVRCVVSSLDTTKGSKKNVMLSLNPKNVNRVLSAETLKPGMLLTGTVSSLEDHGYLVDIGVSGARAFLPLQKAQEYIRQKNKGAKLKVGQYLNCLIEEVKGSRGVVTLSIGHSEVSAAIATEEQSWTLNSLLPGLVVKAQVQKVTPLGLTLKFLSFFSGLVDFMHLDPKKAGTYFSNQQVRACVLCVHPRTRAVRLSLRPVFLQPGRPLTRLLCQQLGAVLDDVPVQGFFGSAGATFKLKDGTLAYARRNHLSNSKKTFKPEAFKPGNTHKCRIIDYSQMDELALLSLRTSIIEAQFLWYHDIKPGALVKGKVLTIKPHGMVVKMGKQIRGLVPTMHLADILIKNPEKKYHVGDEVKCRVLLCDPKAKKLMMTLKKTLVESKLPAITCYDDAKPGLQTHGFILRVKDYGCIVKFYNDVQGLVPRHELSAEYVPDPESVFYTGQVVKVVVLNCEPSKERMLLSFRLLSDPKQEGEGQSQKKKKAVSAGQLADVKVLEKTKDGLKVAVLPHNIPGFLPTAHLSDHVTNGPLLYHWLQTGDTLHRVLCLSVSEERVLLCRKPALVSAVEGGQNPKSFSEIHPGMLLIGFVKNIKDYGVFVQFPSGLSGLAPKAILSDKFVTSTSDHFVEGQTVVAKVTNVDEEKQRMLLSLRLSDCTLGDLATTSLLLLSQCLEERQGVRSLMSNRDSVLIQTLAEMTPGMALDLEVQEVLEDGSVLFSEGPVPGLVLRASKYHRAGQELEPGQKKKAVILNVDMLKLEVHVSLCHDLVNRKAKKLKKGSDLQAIVQHLEESFAVASLVETGHLAAFSLTSHLNDTFRFDSEKLQVGQGVSLTLQTTEPGVTGLLLAIEGPAAKRTMRQTRKDSETVDEDEEVDPALVVGTVKKHTLSIGDVVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPVGTSPTAKLKVGKKVTARVIGGRDMKTFKFLPISHPRFIRTIPELSVRPSELKEDGHTTLNTHSVSPLEKIKQYQPGQTVTCFLKKYNMVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFQIGQALKATVVGPAESSKAFLCLSLIGPHKLKKGEVAMGRVVKVTPKEGLTVSFPFGRVGRVSMFHVSDSYSETHLEDFVPQQVVRCYVLSAATPVLTLSLRSSRTNPETKSKITDPEINSIEDLEEGQLLRGFVKSVQPSGVLVGLGPSVTGLARHPHVSQHNQSKNAPYDRHLPEGKLLTAKVLRLNHQESLVELSLLPDATGKQDVLSAPLGQPPPKQEGRETEAVERNHEGKAKEKKKQKQKEKRTGKGQEGAQPPSKDKKEPQKPQAKKLGKRPHPESSSEQEIGNKKQKKAALSEEDDSGVEVYYREGEEAEEMSMLPKEKLTRPAEAPRLQLSSGFVWDVGLDTLTPALPPHGDSSDSEEDEKPEQATQKKKSKKERELEKQKAEKELSRIEEALMDPGRQPESAEDFDRLVLSSPSSSLLWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYTKSEKFQEAGELYNRMLKRFRQEKAVWVKYGAFLLRRGKAEASHRVMQRALECLPKKEHVDVIAKFAQLEFQLGDAERARAIFESTLSIYPKRTDVWSVYIDMIIKHGSQKEARAIFERVIHLSLAPKRMKFFFKRYLDYEKQHGSEKDVQAVKAKALEYVEAKSSMMDD
What is the function of this protein?
Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor.  Directly interacts with U3 snoRNA (By similarity).
What are the official names of this protein?
Protein RRP5 homolog, Programmed cell death protein 11.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL34_XANOM
Sequence: MATKRTFQPSNLKRARDHGFRARMATADGRKILARRRAKGRKRLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: COFE_METM7
Sequence: MITERVKMEVIGLEIPLISGNEDYTLAELISKYPLKDKDIIVIAETVVSKSEKNVILKDTIKPSNEAIELSKKLGKEPEVVQVILDESNETVRLGPNFIVTETKHGFVCANSGVDESNTSKGIKPLPKNPDKSANEIRKGIEEITGKNVGVIINDSMGRPFRKGSCGVAIGVSGVCGLWDRKGEKDLFGRELKTTEVGIADELAATASVVMGQSNEGIPLVIIRNAPVPFNDGTGKELIRKKEEDVFR
What is the function of this protein?
Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
What are the official names of this protein?
Coenzyme F420:L-glutamate ligase, Coenzyme F420-0:L-glutamate ligase, Coenzyme F420-1:gamma-L-glutamate ligase.
What is the protein family that this protein belongs to?
Belongs to the CofE family.
Protein: PLYX_DICCH
Sequence: MKYAASGLLSVALNSLLLLGSNQRFATQDVAPVWRGIAFGQSTDVNFATNVLPEKVGVNDVTINGKKLTVNDKADLSAPITIESRGGKIANTHDGLTFFYTQLPANVNFTLQSDVTVEQFGPESDAKPNAQEGAGLLVRDILGVPRQEPLKEGYEEFPAASNMVMNAIMTQDKKSKTEVKMQLISRNGVTQPWGNTNAEITRTSYQEKINLEQTPTFRLKLERTNDGFITAYAPKGSDQWVSKTVKGADLVTHQDKDHYYVGFFASRNAKITISNASLTTSPANTKPSAPFKAETTAPLLQVASSSLSTSDTYPVQARVNYNGTVEVFQNGKSLGKPQRVRAGDDFSLTTRLTQQKSDFKLVYIPSEGEDKTAKETSFSVEKITLADARNLYVSPEGKAGNDGSKNAPLDIKTAINALPGGGTLWLMDGDYSATVIPVSATQRKGMKTLMPVGKKAVFHGLQLNASYWKVKGIEITEKSFRIEGSHNQIERLLAHHCDNTGIQVSSSDNVGRPLWASHNLILNSESHSNQHPSKKDADGFAVKMRVGEGNVIRGAFSHDNVDDGFDLFNKIEDGPNGAVMIENSISLNNTSNGFKLGGEGQPVAHQVKNSIAIGNHMDGFSDNFNPGALQVSNNIALDNVRFNFIFRPSPYYGYEKQGIFKNNVSLRTQPGKYDDAVVGRLDASNYFIRIIERSTVRVRKSRRRITNPSRCQRSSAGMKKAACNWVIFCRRSNRHKTQRHRNRYPSTPA
What is the function of this protein?
Exo-cleaving lyase that catalyzes the digestion of pectate.  Contributes to pectate catabolism but not to bacterial virulence.  In vitro can also use citrus pectin and highly methyl-esterified Link pectin as substrates.
What are the official names of this protein?
Pectate disaccharide-lyase, Exopolygalacturonate lyase, ExoPL.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPD_SHESA
Sequence: MAELTTIARPYAKAAFDVAVEHNAVDTWAEMLTFAALVSENETMQPLLTGSLASTKLAALFISVCGEQINEQGQNLIKVMAENGRLKVLPAVSELFAQYRNEWAKEVEADVVSAAELSSEQQQQISNSLEKRLARKVKLNCSTDAALIAGVIIKAGDLVIDGSVRGKLSRLSEKLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PDXS_METAC
Sequence: MTFMDFEKLRHGTELIKRGFARMQKGGVIMDVTTPEQARIAEEAGAVAVMALQAVPADIRKAGGVARMADPEIVQQIIETVTIPVMAKARIGHFVEAEILEALGVDMVDESEVLTPADPFYHIDKTQFTVPFVCGARNLGEALRRINEGAAMIRTKGEAGTGDVSQAVKHMKQIQGEIRALAGKTKEELIMVAREIEAPIELVVETAKMQRLPVVNFAAGGVATPADAALMMRLGADGVFVGSGIFKAENPEKMAKAVVEAVNNYDNPVKLAEISKGVGAGMKGISADMIPAQEALQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: IF1_THEM4
Sequence: MSNKEDIIKMEGTIVEALPNAMFRVELENGHKILAHISGKMRKNFIRLVPGDKVVVELTIYDLTKGRIVYRKKS
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP3_ARATH
Sequence: MASIATSASTSLQARPRQLVIGAKQVKSFSYGSRSNLSFNLRQLPTRLTVYCAAKPETVDKVCAVVRKQLSLKEADEITAATKFAALGADSLDTVEIVMGLEEEFGIEMAEEKAQSIATVEQAAALIEELLLEKAK
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 3, chloroplastic, ACP-3.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GTR12_DANRE
Sequence: MDAPEESIRMTSDPQSKIYVQNPDTHIHLEQGPSAKSGNGRALVLCSVSVACLSGLLMGYEMSLISGALLQLRDVLTLSCPEQEQVVGSLLLGAFLLSLGGGTILDHYGRRFTIILTALLCVLGTLLSVCVVSFWALVVGRMLVGMSVALSGTASCLYAAEVAPAAWRGRCVCVYELMVVLGMLLGFGLSWAFAGVPDGWRFTFGGALLPALLQAGVMPLLPDSPRFLLAQQREKEAHATLLRLRAGIKEVEPVEDELRAIRLAMGAERLHGFLDLFQSRDNMLQRLLVGAALVFLQQATGQPNILAYASTVLSSVGFHGNEAATLASTGFGVVKVGGTIPAIFLVDKVGPKALLCVGVVVMMLSTATLGAITMQSRTHVSSLCRGPGNTANFTLFETGDETDIQTNTPLGLYQPQNKLKTNTFLTSINDTREHWILNHTYNHRTALMETAELSKKDSAKIALQSLHEVSPSLKWISLVSLLVYVAGFSISLGPMVHVVLSAIFPTGIRGKAVSVISAFNWATNLLISMTFLTLTERIGLPTVIFSYSAMSFLLVVFVIVFVPETKGRSLEQISKELAMKNHLRGTLLCHRRKHKATAQPSQEEKALATV
What is the function of this protein?
Insulin-regulated facilitative glucose transporter.
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 12, Glucose transporter type 12, GLUT-12.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Note=Localizes primarily perinuclear region in the absence of insulin.
Protein: TR109_RAT
Sequence: MEHFLKSIFDISKNVLPIILFIELIIGIIGNGFMALVHCMDWVKRKKMSLVNQILTTLATSRICLLWFMLLGLLITLLDPDLASARMMIQVASNLWIIANHMSIWLATCLTVFYFLKIANFSSSLFLYLKWRVEKVISVIFLVSLVLLFLNMLLMNLENDMCIAEYHQINISYSFIYHYRADCERRVLRLHIIILSVPFVLSLPTFLLLIFSLWTHHKKMQQHVQGRRDASTTAHFKALQTVIAFLLLYCIFILSMLLQFWKYELMKKPLFILFCHIVYGAFPSFHSYVLILGDMKLRQASLSVLLWLKCRPNYIETLDL
What is the function of this protein?
Putative taste receptor which may play a role in the perception of bitterness.
What are the official names of this protein?
Taste receptor type 2 member 109, T2R109, Taste receptor type 2 member 38, T2R38.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PHC2_HUMAN
Sequence: MENELPVPHTSSSACATSSTSGASSSSGCNNSSSGGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQHLMLQTAALQQQHLSSAQLQSLAAVQQASLVSNRQGSTSGSNVSAQAPAQSSSINLAASPAAAQLLNRAQSVNSAAASGIAQQAVLLGNTSSPALTASQAQMYLRAQMLIFTPTATVATVQPELGTGSPARPPTPAQVQNLTLRTQQTPAAAASGPTPTQPVLPSLALKPTPGGSQPLPTPAQSRNTAQASPAGAKPGIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPSSKHLQPQFVIQQQPQPQQQQPPPQQSRPVLQAEPHPQLASVSPSVALQPSSEAHAMPLGPVTPALPLQCPTANLHKPGGSQQCHPPTPDTGPQNGHPEGVPHTPQRRFQHTSAVILQLQPASPPQQCVPDDWKEVAPGEKSVPETRSGPSPHQQAIVTAMPGGLPVPTSPNIQPSPAHETGQGIVHALTDLSSPGMTSGNGNSASSIAGTAPQNGENKPPQAIVKPQILTHVIEGFVIQEGAEPFPVGRSSLLVGNLKKKYAQGFLPEKLPQQDHTTTTDSEMEEPYLQESKEEGAPLKLKCELCGRVDFAYKFKRSKRFCSMACAKRYNVGCTKRVGLFHSDRSKLQKAGAATHNRRRASKASLPPLTKDTKKQPTGTVPLSVTAALQLTHSQEDSSRCSDNSSYEEPLSPISASSSTSRRRQGQRDLELPDMHMRDLVGMGHHFLPSEPTKWNVEDVYEFIRSLPGCQEIAEEFRAQEIDGQALLLLKEDHLMSAMNIKLGPALKIYARISMLKDS
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
What are the official names of this protein?
Polyhomeotic-like protein 2, hPH2, Early development regulatory protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_NEIMA
Sequence: MTLGLVGRKVGMTRVFDEQGVSVPVTVLDMSANRVTQVKSKDTDGYTAVQVTFGQKKANRVNKAEAGHFAKAGVEAGRGLIEFALTEEKLAELKAGDEITVSMFEVGQLVDVTGTSKGKGFSGTIKRHNFGAQRTSHGNSRSHRVPGSIGMAQDPGRVFPGKRMAGQYGNTKATVQKLEVVRVDAERQLLLVKGAVPGAVNSDVVVRPSVKVGA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.