PharMolix/UniProtQA huggingface dataset:
Protein: XGPT_VIBCH
Sequence: MSKKFVITWDNMQHYCRELAQRQMPAEQWKGILGVSRGGLVPAAILARELGIRYVDTVCISSYDHDHQRDMTVLKAPEHDGEGFLIIDDLVDSGDTARKIREMYPKAKFVTVCAKPAGKDLVDEYVVDIPQDTWIEQPWDMVLSYVEPVNRKQK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PHS_SHEPA
Sequence: MTELAQMKCEACQADAPKVTDEELAQLIAKIPDWGVEVRGGVMQLERVYKFKNFKLAMEFTNKLADLAEADFHHPGILTEWGKVTVTWWSHSIKGLHKNDFIMAAKTDTLFQ
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: VNS1_BTV20
Sequence: MERFLRKYNISGDYANATRTFLAISPQWTCSHLKRNCLSNGMCAKQNFERAMIAATDAEEPIKAFRLIELAKEAMYDRETVWLQCFKSFSQPYEEDIEGKIKRCGAQLLEDYRKSGMMEEAIKQSALINSERVRLDDSLSAIPYIYVPIKEGQIVNPTFISRYRQIAYYFYNPDAADDWIDPNLFGVRGQHHQIKREVERQINTCPYTGYKGGIFQVMYLPIQLINFLRMDDFAKHFNRYASMAIQQYLRVGYLEEIRYVQQLFGKVPSGEFPLHQMMLMRRDFPTRDRNIVEARVKRSGDENWQSWLLPMVLVREGLDQQEKWEWLLEYMDRKHICQLCYLKHSKQIQTCSVIDVRASELIGCSPFRTVKIEEHVGNEPVFKTKLIRDQQIGRIGDHYYTTSCYTGAEALVTTAIHIHRWIRGCGIWNDEGWQEGVFMLGRVLLRWELTKAQRSALLRLFCFVCYGYAPRADGTVPDWNNLGSFLDIILKGPELSEDEDERAYATMFEMVRCIITLCYAEKVHFAGFTAPACESGEVINLAARMSQMWMEY
What are the official names of this protein?
Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the orbivirus non-structural protein NS1 family.
Protein: EF1A_CENSY
Sequence: MTAHMADKPHLNMIVTGHIDNGKSTTMGHFLMDLGVVDERTIAQHAEESEKTGKGDTFKYAWVMDNIKDERERGITIDLAFQKFETPKYFFTLIDAPGHRDFIKNMITGASEADCAILVLSAKEGETDTAIAAGGQAREHAFLLKTLGVNQLIVAVNKMDDSKYSEEAYKKTVEKGEGLVKSVGYKLENVPFIPVSGWKGDNLVKRSENMPWYKGKTLLESFDDFKMAEKPVGKPLRVPIQDVYTITGVGTVPVGRVETGTMKPGDKIVVMPSGAQGEIKSIETHHTEMPSAEAGDNIGFNLRGIEKKDIKRGDVLGDPANPPKVAKEFLAQIIVIHHPTALAPGYTPVMHCHTAQVAAIMSEFVSKINPATGAVEEENPKFLKVGDSAIIKIRPVRPTPIETFKEFPEMGRFALRDMGATIAAGIVKEITEEHKV
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSPJ_DICDI
Sequence: MSCSIILPNLINFINNDNNNIFEKNNEIQKQQQEEENKSNQVNNILNSIIESKFTSLNPKLKIQETPNQYQIKALIPLNFNKEEISVNVKNNRLIISAFKEIKFENQEKTKLTKFEKYQKTINVSNKNLDFSSIKAQFKDNTLTITIFKQSFEKEIKINIE
What are the official names of this protein?
Small heat shock protein hspJ.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: GLGC_SACD2
Sequence: MLDPNSRYVSRLTRDTVALVLAGGRGSRLHELTDWRAKPALHFGGKFRIIDFPLSNCVNSGIRRIGILTQYKAHSLIRHVIRGWSSFKKEFGEYVEILPASQRYSPNWYQGTADAIYQNLDILQAEAPKYILVLSGDHVYQMDYGAIIAHHVETGADLTVSCIEVPIEEAAGSFGVMTVDDDNRIIRFDEKPQRPTELANKPGYTLASMGNYVFNTEFLFDQLRKDAADPDSEHDFGKNIIPNIIAEKLVSAYRFRDHDTNETAYWRDVGTLDSFWEANMELVSPNPSLNLYNHDWPIWTYQTQLPPAKFVFDDDSRRGYAVDSMVSGGCIVSGGKVKSSLLFSDVHIHSYAEIEESVLLPEVEVHRSAKIKKAIIDSACVIPEGMIIGHDHEHDKARGFRVTKKGVTLVTREMLGQQPAGTSAK
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PA_I67A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFRQSERGEETIEERFEITGTMRRLADQSLPPNFSCLENFRAYVDGFEPNGYIEGKLSQMSKEVNAKIEPFLKTTPRPIRLPDGPPCFQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYIVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPRTKNMKKTSQLKWALGENMAPEKVDFDNCRDISDLKQYDSDEPELRSLSSWIQNEFNKACELTDSTWIELDEIGEDVAPIEYIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQMSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEDGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLVVQALRDNLEPGTFDLGGLYEAIEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: RECX_SALPB
Sequence: MSEPTSRRPAYARLLDRAVRILAVRDHSEQELRRKLSAPVMGKNGPEEIDATADDYERVIAWCHEHHYLDDERFVMRFIASRSRKGYGPARIRQELNQKGISRESTEKAMRECEIDWSEMAREQAVRKYGEPLPSNFSEKVKVQRFLLYRGYLMDDIQQIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAAL1_MOUSE
Sequence: MDRNPSPPPPTCGSEDEEDLGGGDRIGSTVYSKHWLFGVLSGLIQIVTPESGTSGSADEEEQADLAEEMENEICRVWDMSMDEDVALFLQEFKAPDIFMGVLAKSPCPRLREICVGILGNMACFREICESISKNEDHGQVLLQCLCDSDPPTLLETCRLLLTCLSQTEVASVWVRRIREHPSVYANVCFIMSSSTNVDLLVKVGEVVDKLFDLDEKLMLEWIRKGATRLPGQPHEDSEEQPVFSIVPCVLEAAKQVRSENLEGLDVYMRILQLLTTVDDGVQAIVQCPDTGNDTWRLLFDLVCHEFCQPDDPPVILQEQKTVLASVFSVLSAISASRAEQEHLKIEEGDLPLIDSLIRVLQNMEHCQKKPENPSESDTEEPTICGPTQDDFHMKILKDISCEFLSNIFQVLTKEKVAQGLKEGQLSKQKCSCAFQSLLPLYGPAVEDFVKVVREVDEALADDLEDSFPSVKAQT
What is the function of this protein?
Plays a role in promoting the proliferation of synovial fibroblasts in response to pro-inflammatory stimuli.
What are the official names of this protein?
Protein SAAL1, Synoviocyte proliferation-associated in collagen-induced arthritis protein 1, SPACIA1.
What is the protein family that this protein belongs to?
Belongs to the SAAL1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARAA_PECAS
Sequence: MDHFKQLEVWFVIGSQHLYGPETLRQVKENAEKVVAGLNQQANLPVKLVLKPLVKTPDEILALCRDANYQDNCIGLLTWLHTFSPAKMWIGGLSVLSKPLLQFHTQFNAEVPWDTMDMDFMNLNQTAHGGREFGFIGARMRQAHQVVVGHWQDKNAHVRIGKWMRVAAAIQESKQLKVARFGDNMREVAVTEGDKVGAQIQFGYSVSAWGLGDLTAVVDAVSKGDIDALIEEYETSYQLTDAVKLNGANRQNLLDAAQIELGMKRFLEQGGYHAFTTDFENLYGLKQLPGLAVQRLMQQGYGFGGEGDWKTAALLRIMKVMAGGLSGGTSFMEDYTYNFQNGNDLVVGSHMLEVCPTIAKEQKPILDAQHLGIGGKADPARLIFSTPAGPSLNASVIDMGDRFRMLVNLVDTIEQPRPLPKLPVARAIWKAQPSLEVAAEAWILAGGAHHTVFSQALDLDHMRLYAEMQNIELLVIDNETRLHEFKDALRWNEVYYKLCSR
What is the function of this protein?
Catalyzes the conversion of L-arabinose to L-ribulose.
What are the official names of this protein?
L-arabinose isomerase.
What is the protein family that this protein belongs to?
Belongs to the arabinose isomerase family.
Protein: MPP7_HUMAN
Sequence: MPALSTGSGSDTGLYELLAALPAQLQPHVDSQEDLTFLWDMFGEKSLHSLVKIHEKLHYYEKQSPVPILHGAAALADDLAEELQNKPLNSEIRELLKLLSKPNVKALLSVHDTVAQKNYDPVLPPMPEDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAIIVARIMRGGAADRSGLIHVGDELREVNGIPVEDKRPEEIIQILAQSQGAITFKIIPGSKEETPSKEGKMFIKALFDYNPNEDKAIPCKEAGLSFKKGDILQIMSQDDATWWQAKHEADANPRAGLIPSKHFQERRLALRRPEILVQPLKVSNRKSSGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDDQGAAKPFTEEDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETETHWVPVSWLHS
What is the function of this protein?
Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1.  Involved in the assembly of protein complexes at sites of cell-cell contact.
What are the official names of this protein?
MAGUK p55 subfamily member 7.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Lateral cell membrane; Peripheral membrane protein. Cell junction, tight junction. Cell junction, adherens junction. Cytoplasm, cell cortex. Cytoplasm. Note=In epidermal cells, detected primarily at the lateral cell membrane.
Protein: QUEA_YERPE
Sequence: MRVADFSFELPEALIAHYPQPQRSGCRLLSLDGPTGTLTHGIFTDLLDKLAPGDLLVFNNTRVIPARLFGRKASGGKLEVLVERVLDDHRVLAHVKASKAPKPGAELLLGDDESIRATMLARHDTLFELRFDDERDVFTILNAVGHMPLPPYIDRPDEDADRELYQTVYSQRPGAVAAPTAGLHFDEPMLAALQEKGIEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQEVVDAVLACKARGKRVVAVGTTSVRSLESAAKAAENGLIAPFFGDTRIFIYPGYHYQVVDALVTNFHLPESTLIMLVSAFAGYKNTMNAYQQAVAEQYRFFSYGDAMFISRNPRAPQEKVSP
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTA_STRCO
Sequence: MTRSVYVTGIDRGDGRQVVELGVMELLTRQVDRVGVFRPLVHDGPDRLFELLRARYRLSQDPATVYGMDYQEASLLQAEQGVDELVSALVDRFHLVARDYDVVLVLGTDYADTQFPDELSLNARLANEFGASVLPVVGGRKQTADSVLAETHNAFRAYDGLGCDVLAMVTNRVAREDRDEIAERLAHRLPVPCWVVPDEPALSAPTVSQIAHALGAEIVLGDDSGLARDALDFVFGGAMLPNLLAALTPGCLVITPGDRADLVIGTLAAHSAGTPPIAGVLLTLNEVPGEGILTLAARLAPGTPVLSVTGTSFPTAERLFSLEGKLGAATPRKAETALGLFERYVDTAELNKRVSAPSSDRVTPMMFEHKLLEQARSDLRRVVLPEGTEERVLHAAEVLLRRGVCELTLLGPVEQIRKKAADLGIDLGGAELIDPAASELRDSFAEKYAALRAHKGVTVELAYDVVSDVNYFGTLMVQEGFADGMVSGSVHSTAATIRPAFEIIKTKPDAAIVSSVFFMCLADKVLVYGDCAVNPDPDAEQLADIATQSASTAAQFGVEPRIAMLSYSTGTSGSGADVDKVREATELVRSRRPDLSVEGPIQYDAAVEPSVAATKLPGSAVAGQASVLIFPDLNTGNNTYKAVQRSAGAIAVGPVLQGLRKPVNDLSRGALVQDIVNTVAITAIQAQQSPTEKASAQ
What is the function of this protein?
Involved in acetate metabolism.
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFLD_SHESW
Sequence: MNEQLINRTMAFAGILQAIAQVQHLARHGELDNAELAASLNTILVTNPDNTADVYPDKIVLQKGYKLILNQLGDSSQKDVEITRYLVGVLALERKLVRSNSGLGMLAERINQVNRQLHHFAITDEQVVANLASIYSDIISNLGPKIQISGNPVCLQRPIVQHKIRALLLAAIRSAVLWRQLGGKRRHLVFARKAIVDTAKKSLTL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CLPS_STRCO
Sequence: MEIEKTESAEEVFAVPEPDVPWVTIVHNDPVNLMSYVTYVFQSYFGYSKDKATKLMMDVHHKGRAVVSSGSREEMERDVQAMHGYGLWATLQQDRK
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RF1_METM6
Sequence: MSGNSSTDMYLFKKSLKELKGKKGKGTELISVYVPAGRRLSDISQYLRQELSQSSNIKSKTTMKNVQSAIEVILQRLKLLKEPLEMGVIIFAGMIPRGGPGTEKMEVYVLEPPEPVKTFVYRCDSLFYTDPLEDFIQDTEVYGVILVDRNEATIGTVKGKTITVLKKLTSGVPGKFKAGGQSARRLERLIDDAAHQFMVRIGEYATESFMPILEEKKLKGLLLGGPGNTKNEFAEKDYLHHELKKKIIDTFDLCYTEEFGIRELLDKASDLLRDLDLMKEKNLIQRFFKELIKDDGGLSAYGEAQVMKYLEMGAIDTLIVTEDIGITRVTIKCNNCDYTQEVNVKTNEMFKFEEQLKTKACPTCGGAMYIDEEKDIIEHLSDLCNVHNTDIIVVSTDTEEGSQISRAFKGMAAILRYKL
What is the function of this protein?
Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.
What are the official names of this protein?
Peptide chain release factor subunit 1, Translation termination factor aRF1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGGA_PETMO
Sequence: MNNLYIFHYHYIKGGVSTVVRNIVKSLKDAYKITLFGSKKMGIDGIEEVLSYENVDFIDFPELGYIYYDSTDYKTFLELKESIKNKLNNYHDERAIYWAHNYNLGKNPAFTEAFKEFITTKNIPTIIQIHDFPECARWENYSFIRKFINSSLYPIRKNIQYATINLSDYNRLIKCGIPSENAFYLPNAVEFAKNKDKIDDIDKDEVINKLKKLGYNVDPTNKNILYPTRTIRRKNILEAVLINRLYGKSNLLVTLPANSDKERPYEKVVKETFESEKVKGAWAISAKDPSLFPYILNISDLFFSSSVLEGFGMIYLESKFNEKNFLTRKLDVIEDFKNIKEISYYDRFLVSLSPKEINKVKEKYEEQINKIPISEENKNHLRQDLNNKFDKDLIDFSFLPVELQKKFCMEEEAKLNDLKEINKEIFDKIEMLTSTNHIDQGINLEDFSLKAYKSKIFLLLDKVQARGNAPKGVQGSTKEIEDTIIDENILKSFLTIDNIRLLFSY
What is the function of this protein?
Involved in the biosynthesis of the compatible solute mannosylglucosylglycerate through a phosphorylating pathway.  Catalyzes the conversion of glucosyl-3-phosphoglycerate (GPG) to mannosylglucosyl-3-phosphoglycerate (MGPG).
What are the official names of this protein?
Mannosylglucosyl-3-phosphoglycerate synthase.
Protein: FPG_JANSC
Sequence: MPELPEVETVRRGLAPVLEGARIAQAAVNRPDLRWPFPDNMAQRLTGATVTALRRRSKYILADLDTGETLLIHLGMSGRMQISGDVIGSFHHTHPAAAKHDHVVLDTDAGARITFNDARRFGAMDLMDTATQDQHWLLRDLGPEPLGNAFNEAHLVAAFKGKRSPVKTALLDQRIVSGLGNIYVCEALWRAGISPLRQAGKIAAVRVATLVPIIRDVLTEAIEAGGSSLRDHRQATGELGYFQHTFRVYGREGQRCQTPDCAEKILRKVQSGRSSFYCPACQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LIPC_BACLD
Sequence: MTLQYTALGDSLTVGVGAGLFEPGFVQRYKRKMEEDLNEEVSLIVFAKSGLETSEILAMLNEPFIMEQVKKADVITITGCGNDLLQSLEIYEKEKDEHVFLEASSHCQKNYSGMLEKIREIKGEKDTRYLVRLLNLYNPFPSIELADKWISGFNRHLKQLESAPQIKVIDTYAVFKGREKEYLSIDRVHPSSRGYEAMSEKLRAAGYGRLEG
What is the function of this protein?
Lipase involved in spore germination.
What are the official names of this protein?
Spore germination lipase LipC.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Spore coat.
Protein: BIOH_ALIFM
Sequence: MTTSLYWQTEGEGSDLVLIHGWGMNGAVWQTTSEKLSQHYRVHTVDLSGYGHSAELGSADFDEMVKQVLAQAPKKAAWLGWSLGGLIATKAALTSPERVSQLITVASSPCFSAEKGWRGIKPLILSQFTEQLKTDFTLTVERFMALQAMGSPNAKQDIKLIKKAVFSRPMPDQQALATGLMILADIDLREAVSQLSMPVCRMYGRLDGLVPIKVAHYMDELMPNSAKIVFEQASHAPFISHNDEFISELRTFLNQHA
What is the function of this protein?
The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters.
What are the official names of this protein?
Pimeloyl-[acyl-carrier protein] methyl ester esterase, Biotin synthesis protein BioH, Carboxylesterase BioH.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Carboxylesterase BioH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATE_THEAC
Sequence: MDTKIGLEVHFQLNTGKLFCRCPVEQSSGELMRFSRKLHISASELGNIDAAASYESMRSRSFQYVVTDNSCLVEMDEEPPKTPDERAIATAISVSKALNCDIVDHITYMRKIVIDGSNTTGFQRTAIVGINGHIETSKGPVRISTVCLEEDAARKIEEIGNTVVYSLDRLGIPLIEISTEPDIVDEDHAVEVARSIGYIVISTGNARHAVDAVRQDVNFSMGYGRVEIKGVSKLTQIRDVIRYEKERQENLRAAVDLIKSRGGLDRVSFNLKDVSDLFAGTKSKIIRSGIESGGVYAGILKNMAGTLKNGKLRMGKEIADLVRSYGIKGVMHSDELPGYGLTQDEVEALYRYLGKGDNDAVLLIAINQSRVKMIENSIFDRIQKIISMDLSETRGPAGEETVFLRPMPGKDRMYPETDIPVIKVDSKLMEMSSSIKPRTYAEVVQDLVDRYGISKQNAEYIASEMVVDAFRNIAEFVEAREAARILTQIVPDLERRTKKIIDHDRIIELCRRSKDLHFDRYQLEMALEILYERDDVASVLGDSRLKELSREEIKSIIREILSSGRNATQNSIIALIKEKTERVFDPRVAMECFNEVKNKNNVF
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  The GatDE system is specific for glutamate and does not act on aspartate.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit E, Glu-ADT subunit E.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatE subfamily.
Protein: NLTP_MORCI
Sequence: AVPCGQVSSALSPCMSYLTGGGDDPEARCCAGV
What is the function of this protein?
Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes (By similarity).  May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues (By similarity).  Has antibacterial activity against Gram-positive bacteria S. aureus and S. epidermidis and blocks biofilm formation (PubMed:29577952).  In a mouse model, also protects against bacterial sepsis and has an anti-inflammatory effect (PubMed:29577952, PubMed:28559184).  Exhibits antinociceptive activity upon oral or intraperitoneal application in mice (PubMed:26783638).
What are the official names of this protein?
Non-specific lipid-transfer protein, McLTP1.
What is the protein family that this protein belongs to?
Belongs to the plant LTP family.
Protein: AHPF_STAAC
Sequence: MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKDLLTEITDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKKLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMNTGEEHLLNLDGIFVQIGLLPNTSWLNDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
What is the function of this protein?
Serves to protect the cell against DNA damage by alkyl hydroperoxides.  It can use either NADH or NADPH as electron donor for direct reduction of redox dyes or of alkyl hydroperoxides when combined with the AhpC protein (By similarity).
What are the official names of this protein?
Alkyl hydroperoxide reductase subunit F.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
Protein: TRUB1_RAT
Sequence: MAAEEAEVVSPLIVDTAPDTSGTAAASLAAAVSAAAAAARTGSQAQVSKAALAAKLMSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGLPSPEWNKRQKQTLKVGHGGTLDSAAQGVLVVGIGRGTKMLTSMLSGSKRYIATGELGKATDTLDSTGKVTEEKPYDKITQEDIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGETVEARPARPVTVHSISLLKYQPPFFTLDVECGGGFYIRSLVSDIGKELSSCATVLELTRTKQGPFTLAQHALPEDRWTINDIAQSLKRCTSLLPEELTFKKSKSEPSSDQALSCGYITLRETKREDDTVKTL
What is the function of this protein?
Pseudouridine synthase that catalyzes pseudouridylation of mRNAs and tRNAs.  Mediates pseudouridylation of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harboring a stem-loop structure.  Constitutes the major pseudouridine synthase acting on mRNAs.  Also catalyzes pseudouridylation of some tRNAs, including synthesis of pseudouridine(55) from uracil-55, in the psi GC loop of a subset of tRNAs.  Promotes the processing of pri-let-7 microRNAs (pri-miRNAs) independently of its RNA pseudouridylate synthase activity.  Acts by binding to the stem-loop structure on pri-let-7, preventing LIN28-binding (LIN28A and/or LIN28B), thereby enhancing the interaction between pri-let-7 and the microprocessor DGCR8, which mediates miRNA maturation.
What are the official names of this protein?
Pseudouridylate synthase TRUB1, TruB pseudouridine synthase homolog 1, tRNA pseudouridine 55 synthase TRUB1, Psi55 synthase TRUB1.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Note=Catalyzes pseudouridylation of mRNAs in the nucleus.
Protein: GANAB_MOUSE
Sequence: MAAIAAVAARRRRSWLSLVLAYLGVCLGITLAVDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPGVSVASDWSIHLR
What is the function of this protein?
Catalytic subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:27462106).  Required for PKD1/Polycystin-1 and PKD2/Polycystin-2 maturation and localization to the cell surface and cilia (PubMed:28375157).
What are the official names of this protein?
Neutral alpha-glucosidase AB, Alpha-glucosidase 2, Glucosidase II subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Melanosome.