PharMolix/UniProtQA huggingface dataset:
Protein: COB21_ARATH
Sequence: MPLRLEIKRKFAQRSERVKSVDLHPTEPWILASLYSGTLCIWNYQTQTMVKSFDVTELPVRSAKFIARKQWVVAGADDMFIRVYNYNTMDKIKVFEAHADYIRCVAVHPTLPYVLSSSDDMLIKLWDWEKGWLCTQIFEGHSHYVMQVTFNPKDTNTFASASLDRTIKIWNLGSPDPNFTLDAHLKGVNCVDYFTGGDKPYLITGSDDHTAKVWDYQTKSCVQTLEGHTHNVSAVSFHPELPIIITGSEDGTVRIWHATTYRLENTLNYGLERVWAIGHIKGSRRVVIGYDEGSIMVKLGREIPVASMDNSGKIIWAKHNEIHTVNIKSVGADEVTDGERLPLAVKELGTCDLYPQSLKHNPNGRFVVVCGDGEYIIYTALAWRNRSFGSALEFVWSSDGEHAVRESSTKIKIFSKNFQEKKTVRPTFSAEHIFGGTLLTMCSSDFICFYDWAECRLIRRIDVTVKNLYWADSGDLVAIASDTSFYILKFNRDIVSSYFDGGKQIDEEGIEDAFELLNETNERVRTGLWVGDCFIYTNSSWRLNYCVGGEVTTMYHLDRPMYLLGYLANQSRVYLIDKEFNVIGYTLLLSLIEYKTLVMRGDLEQANEVLPSIPKEHHNSVAHFLESRGMTEDALEVATDPDYRFELAIQLGRLAVAKDIAVEAQNESKWKQLGELAMSSGKLDMAEECMRHAMDLSGLLLLYSSLGDADGMMKLAALAKEQGKNNVAFLCLFMLGQVEDCLHLLVESNRIPEAALMARSYLPSKVSEIVALWRNDLTKISPKAAESLADPEEYPNLFEEWQVALSLENRAAETRGVHPPAGDYCSHADRDHTTLVDAFRIMQIEEEGRLEQGDVLDEVGEEGEDGEEEEEEDRQEESSDGRQQNVEEEAVVVDADSTDGAVLVNGNESEEQWVLTPPQE
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit beta'-1, Beta'-coat protein 1, Beta'-COP 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat COPB2 family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: MNMG_MYCAP
Sequence: MNKKYDAIVIGGGHAGLEAAFAISHKGRNTLLLTFNSKKLGMMPCNPSIGGPAKGIITREIDALGGMQGLWADLATIQLKMLNLSKGPAVRALRAQIDKEKYSQLAYEYVLKQPNLELLEGVAEEVIVDENGYFKGVLVENIGLIEAKVCVITTGTYMNSRILRGQDITTSGPDNEKTTPKLSASLAKLGFTLQRLKTGTPPRIYSDSINFDEVEQEVLSDVNISFSSRSNLKKPKQIACYLTYTTPETHRIIEENIHRSPMYSGVIEGIGPRYCPSVEDKIVKFPDKERHQIFFEPETADGAITHVNGLSTSMPIDVQELMIKSIPGLRNAKVQKWAYAIEYDALDPLQLKESLETKLVHNLFTAGQINGTSGYEEAAAQGLIAGINAALKLEDKDPIVILRNHGYIGVLIDDLVTKGTKEPYRMLTSRAEYRLLLRNDNADDRLSEYAYNSGMISKEEYQKVLDKYKLIDDEIQRLNTTYLSGKSDVALKYNITNGSTLLNVISRPDVDPSDIIPNFPYLEEITTMVRLHGYIEKQKSDANKAVRLENLKIPEDLNYLDVKNIAIEARQKFEKIRPATIGQASRISGINPADIQMLMFHLESRNKKNYDQN
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_RAT
Sequence: MATEEAIIRIPPYHYIHVLDQNSNVSRVEVGPKTYIRQDNERVLFAPVRMVTVPPRHYCIVANPVSRDTQSSVLFDITGQVRLRHADQEIRLAQDPFPLYPGEVLEKDITPLQVVLPNTALHLKALLDFEDKNGDKVMAGDEWLFEGPGTYIPQKEVEVVEIIQATVIKQNQALRLRARKECFDREGKGRVTGEEWLVRSVGAYLPAVFEEVLDLVDAVILTEKTALHLRALQNFRDLRGVLHRTGEEWLVTVQDTEAHVPDVYEEVLGVVPITTLGPRHYCVILDPMGPDGKNQLGQKRVVKGEKSFFLQPGERLERGIQDVYVLSEQQGLLLKALQPLEEGESEEKVSHQAGDCWLIRGPLEYVPSAKVEVVEERQAIPLDQNEGIYVQDVKTGKVRAVIGSTYMLTQDEVLWEKELPSGVEELLNLGHDPLADRGQKGTAKPLQPSAPRNKTRVVSYRVPHNAAVQVYDYRAKRARVVFGPELVTLDPEEQFTVLSLSAGRPKRPHARRALCLLLGPDFFTDVITIETADHARLQLQLAYNWHFELKNRNDPAEAAKLFSVPDFVGDACKAIASRVRGAVASVTFDDFHKNSARIIRMAVFGFEMSEDTGPDGTLLPKARDQAVFPQNGLVVSSVDVQSVEPVDQRTRDALQRSVQLAIEITTNSQEAAAKHEAQRLEQEARGRLERQKILDQSEAEKARKELLELEAMSMAVESTGNAKAEAESRAEAARIEGEGSVLQAKLKAQALAIETEAELERVKKVREMELIYARAQLELEVSKAQQLANVEAKKFKEMTEALGPGTIRDLAVAGPEMQVKLLQSLGLKSTLITDGSSPINLFSTAFGLLGLGSDGQPPAQK
What is the function of this protein?
Required for normal vault structure.  Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction.  Vaults may also play a role in nucleo-cytoplasmic transport.  Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK.  Down-regulates SRC activity and signaling through MAP kinases (By similarity).
What are the official names of this protein?
Major vault protein, MVP.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SODM_STRCB
Sequence: QFDAETMTLHHDKHHATYVANANAALEKHPEIGENLKELLADVTKIPADIRQALINNGGGHLNHALFWELLSPEKQEITADVAQAIDEAFGSFDAFKEQFTAAATGRFGSGWAWLVVNKEGQLEITSTANQDTPISEGKKPILAL
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.  Catalyzes the dismutation of superoxide anion radicals into O2 and H2O2 by successive reduction and oxidation of the transition metal ion at the active site.
What are the official names of this protein?
Superoxide dismutase [Mn/Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: PN3A_PAMNI
Sequence: DCRYMFGDCEKDEDCCKHLGCKRKMKYCAWDFTFT
What is the function of this protein?
Gating-modifier toxin that targets voltage-gated sodium channels.  According to Deuis et al. , 2017, it shows a preferential activity on Nav1. 7/SCN9A (Nav1. 7/SCN9A (IC(50)=0. 9-4. 4 nM)) (PubMed:28106092).  However, another study shows a much less potent activity on Nav1. 7/SCN9A (IC(50)=1457 nM) (PubMed:31234412).  Also shows weaker effects on hNav1. 1/SCN1A (IC(50)=37 nM), hNav1. 2/SCN2A (IC(50)=124 nM), hNav1. 3/SCN3A (IC(50)=210 nM), hNav1. 4/SCN4A (IC(50)=144 nM), hNav1. 5/SCN5A (IC(50)=800 nM), hNav1. 6/SCN8A (IC(50)=129 nM), hNav1. 9/SCN11A (IC(50)=2427 nM) (PubMed:28106092).  On Nav1. 7/SCN9A, the toxin acts by shifting the voltage-dependence of activation to more depolarized potentials, whereas it does not cause significant effect on the voltage-dependence of activation on other sodium channels (PubMed:28106092).  Minor effects are observed on the voltage-dependence of steady-state fast inactivation for all sodium channels tested (Nav1. 1/SCN1A-Nav1. 8/SCN10A) (PubMed:28106092).  By testing the toxin on channel chimera, it has been shown to interact with the S3-S4 linkers in DII and DIV domains of Nav1. 7/SCN9A (PubMed:28106092).  In vivo, when tested on the OD1-induced mouse model of Nav1. 7/SCN9A-mediated pain, the toxin dose-dependently reduces pain behaviors (PubMed:28106092).
What are the official names of this protein?
Mu-theraphotoxin-Pn3a, Mu-TRTX-Pn3a.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 28 (Jztx-11) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DER_RUEST
Sequence: MSFTLAIVGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDLREGEARLGDLRFTVIDSAGLEDATDNSLEGRMRRLTERAVEMADVCLFLIDARAGVTPTDEVFAEILRKKSAHVILAANKSEGSAADAGVLEAYGLGLGEPIRMSGEHGEGLNDLYSELLPVSEKFEKLAEETAPETDVVLDEDENEAFNAGEEIAATPVPTLEKPLQVAVVGRPNAGKSTLINKILGEDRLLTGPEAGITRDAISLKIDWSGTPMRIFDTAGMRKKAKVQEKLEKLSVSDGLRAVKFAEVVVVLLDAAIPFEQQDLRIADLAEREGRAVVIAVNKWDIEDEKQEKLKALKEAFERLLPQLRGAPLVTVSAKTGRGLDRLHAAIMKAHDVWNRRVPTAALNRWLAGMLEQHPPPAPQGKRIKLRYMTQAKTRPPGFVVMCSHPDKMPASYNRYLVNGLREDFDMPGTPIRLTLRGQGDKNPYKGKKKSTPSRLRKHLEGRKS
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: COPZ1_ORYSJ
Sequence: MESCPSVKNILLLDSEGKRVAVKYYTDDWPTLSAKLAFEKSVFVKTQKATAGAEAEIVMFDGHIVVYKFIQDLHFFVTGGEEENELILASVLQGFTDAVDIILRNNVDKRTALENLDLILLCLDEIVDGGIVLETEGSVIAEKVSAHGIEGATSLAEQTIVQALTTAREHLTKSLLM
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Coatomer subunit zeta-1, Zeta-1-coat protein, Zeta-COP 1, Zeta1-COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: RENT1_TAKRU
Sequence: MSVEAYGPSSQTLTFLDTEETELLGADTQGSEYDFTDFTLPSQTQTQGHTQSQLDNQLNGPDDGLHNGGMDDSVAKASQLLAELNFEEDEEDTYYTKDLPVHACRSYCGIHDPACVVYCNTSKKWFCNGRGNTSGSHIVNHLVRAKCKEVTLHKDGPLGETVLECYNCGCRNVFLLGFIPAKADSVVVLLCRQPCASQSSLKDINWDSSQWQPLIQDRCFLSWLVKIPSEQEQLRARQITAQQINKLEELWKDNPCATLEDLEKPGVDEEPQHVLLRYEDAYQYQNIFGPLVKLEADYDKKLKESQTQDNITVRWDLGLNKKRIAYFTLPKTDSDMRLMQGDEICLRYKGDLAPLWKGIGHVIKVPDSYGDEIAIELRTSVGAPVEIPHNYQVDFVWKSTSFDRMQSALKTFAVDETSVSGYIYHKLLGHEVEDVTIKCQLPKRFTANGLPDLNHSQVYAVKTVLQRPLSLIQGPPGTGKTVTSATIVYHLSRQGNGPVLVCAPSNIAVDQLTEKIDKTGLKVVRLCAKSREAIESPVSFLALHNQISNMDSMPELQKLQQLKDETGELSSADEKRYRALKRTAERELLMNADVIWCTCVRAGDPRLAKMQFRSILIDESTQATEPKCIGPVELGAKQLILGEITASWSCVMCKKAAKAGLSQSLFERLVVLGIRPIRLQVQYRMHPALSAFPSNIFYEGSLQNGVTAGDRIKKGFDFQWPQPEKPMFFYVTQGQEEIASSGTSYLNRTEAANVEKITTRLLKAGAKPDQIGIITPYEGQRSYLVQYMQFSGSLHTKLYQVEIASVDAFQGREKDFIILSCVRANEHQGIGFLNDPRRLNVALTRAKYGVIIVGNPKALSKQPLWNNLLNNYKEQKVLVEGPLNNLRESLMQFSKPRKLVNTINPRFMSTAMYDAREALIPGSAYDRSNTGGRPSNMYFQTHDQIGMIGAAASHLAALNIPIPFNLVMPPMPPPSYQGQTNGPAAGRGAMKGKSGRGGRQRIQWFWEPGGWSHAKQSDQPGWGFPVILSGATDTGLHLHEPAFPDEPARTLPARALPWDSYLGDEFKSQIDVALSQDSTYQGERAYQHGGVTGLSQY
What is the function of this protein?
RNA-dependent helicase required for nonsense-mediated decay (NMD) of aberrant mRNAs containing premature stop codons and modulates the expression level of normal mRNAs.  The formation of an rent1-rent2-rent3 surveillance complex is believed to activate NMD (By similarity).
What are the official names of this protein?
Putative regulator of nonsense transcripts 1, ATP-dependent helicase RENT1.
What is the protein family that this protein belongs to?
Belongs to the DNA2/NAM7 helicase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body.
Protein: Y6564_DICDI
Sequence: MVLENFKWSWISVGVTVGVGVGVCDGDGVGVGIGVGIGVGVSDGVSAGVGVGVAMIIQTSPSACKKYYKLY
What are the official names of this protein?
Putative uncharacterized protein DDB_G0268542.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: OBG_STAAN
Sequence: MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_BUCAI
Sequence: MNYFNTLNFTQKINQINKCRFMKKEEFNKKNDILKNKNIVIVGCGAQGLNQGLNMRDAGLNISYALKKNSIANKNQSWINAIENNFKVDDYDALIPDADLVINLTPDKQHHSVIKKLQKLMKKNAVLGYSHGFNIVEFGEKIRKDITVIMVAPKCPGTEVREEYKRGFGVPTLIAVHHENDINKIGLEVAKAWAFSTGGHRAGVLESSFIAEVKSDLMGEQTILCGMLQTASLLCYEKLITEKCNPAYSAKLIQNGWETITESLKHGGITLMMDRLSNSSKIRAYKLSKEIKKILSPLFQKHMDDIISGEFSNEMMKDWENQDLKLLNWRYKTKNTSFETAPVYNEKIPEQEYYDHGILMIAILKSGIELSFEKMIETGIKEESAYYESLHELPLIANTIARKKLYEMNKVISDTAEYGSYLFSESAYPILKEFISTLNKSDLGCALSHQSVNNIELYRINQKIQNHPIEIIGCTLRNYMKKMKAITVAK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LIPB_RHOOB
Sequence: MSSATQSARFSPSPISVEHLGTIGYVDAWDRQRELAAERAENLGADTLLLLEHPAVYTAGRRTEPEDRPTDGTPVIDVDRGGKITWHGPGQLVGYPIVKLAEPVDVVRYVRRLEQALISVCTDLGIDCGRVDGRSGVWLPASLDNGQWLPERKVAAIGVRVQRGVALHGFSLNCNSVLTGFDAIIPCGIRDAGVTSLSRELGRDVTVEEVTPAVTAAVVAALDGALPVTDHDIERVTFDSATAEKTAAAPTFTTVQYG
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XNI_CROS8
Sequence: MPVHLLIVDALNLIRRIHAVQGTPCVDTCLHALEQLIGNSQPTHAVAVFDDEARAQGWRHQLLPDYKAGRPPMPDDLHQEMPALRDAFTRRGVPCWHVEGNEADDLAATLAVKVAAAGHEATIVSTDKGYCQLLRPEIRIRDYFQKRWLDAPFIESEFGVSPGQLADFWGLAGISSSKIPGVPGIGPKSATQLINDFGTLEALYERLDDVPDKWRKKLEAHRESAFVCRAVATLKTDLQLDGNLQQLRLHG
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: DAPF_ECOLI
Sequence: MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
What is the function of this protein?
Involved in the succinylase branch of the L-lysine biosynthesis and in the biosynthesis of the pentapeptide incorporated in the peptidoglycan moiety (PubMed:3283102).  Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP) (PubMed:6378903, PubMed:3031013, PubMed:3042781).
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_PROMP
Sequence: MNTNHIRTVKGGGSLQGILNVPGDKSISHRSLIIGSIAEGETNIKGFLYSDDPLSTADCLRKLGVNIPEIKKNQPFTIKGLGIDDFKEPEEILDCGNSGTTMRLLMGLLAGQEGRNFILTGDKSLNERPMGRVSKPLSLMGGIIHGRKNGTKAPISITGNKLKGCVIGTPVASAQVKSAILLAGLNASGTTSVIEPASSRDHTERMLKAFGADINIRGELGRNIVIKSGTNLTGQNILIPGDISSAAFWMIAASIVPESEIIIKNVGLNPTRTGILNVMNEMGCNYEILDKSTIAGEPIGSINIKYVSNLKPFKVEGDILPKLIDEIPILAVAACFCSGVSEIKDAKELRVKETDRLKVMATQLKKFGANILEKEDGLIINGESKFHSAEVDSETDHRVSMSLAIASLLAKGSSKIARAEASRVSYPTFWDDLEKLIN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y940_THEON
Sequence: MRKGSVKEVLAKLKYDPREDERDYYIIIEHRGAYGDVKKIPVELIELGHGYFFVGDAQIPYHRIRRVVKKDGKVIWETRKDRRGESD
What are the official names of this protein?
UPF0248 protein TON_0940.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: PG36_MYCTO
Sequence: MSFVIASPEALLAAATDLAAIRSTIRAANAAAAVPTTGALAPAADEVSAGIAALFGAQAQSYQAVSAQAAAFHDRFVQLLNAGGGSYASAEIANAQQNLLNAVNAPTQTLLGRPLVGDGADGASGPVGQPGGDGGILWGNGGNGGDSTSPGVAGGAGGSAGLIGNGGRGGNGAPGGAGGNGGLGGLLLGNGGAGGVGGTGDNGVGDLGAGGGGGDGGLGGRAGLIGHGGAGGNGGDGGHGGSGKAGGSGGSGGFGQFGGAGGLLYGNGGAAGSGGNGGDAGTGVSSDGFAGLGGSGGRGGDAGLIGVGGGGGNGGDPGLGARLFQVGSRGGDGGVGGWLYGDGGGGGDGGNGGLPFIGSTNAGNGGSARLIGNGGAGGSGGSGAPGSVSSGGVGGAGNPGGSGGNGGVWYGNGGAGGAAGQGGPGMNTTSPGGPGGVGGHGGTAILFGDGGAGGAGAAGGPGTPDGAAGPGGSGGTGGLLFGVPGPSGPDG
What are the official names of this protein?
Uncharacterized PE-PGRS family protein PE_PGRS36.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family. PGRS subfamily.
Protein: MAK5_CRYNJ
Sequence: MAKIDKKTKLKLNKKSVRAPSKPTTEKKPKKYVTADTLTWKPVKTSSFSGIDGGGGMMMLEELEDVGIEWEETDGGRKIAKFVEVESKTSKGKKNAAQEEPNQEGRGDDEKASSASETEEGKKADDKEAVEEDDEEEFPDFAGFAEEDLNAADEEEHPNLDDEPAFNDDLLPEWSSISLHPSLKRSFLASSFTAPTAIQSRAIPAGITGRDVVGVAETGSGKTLAYSLPILHYLLGQRKSKAGIKRPLSALVLCPTRELALQVMDHLNALLKHALATPDGEKPQGPPRVSVGSVVGGLSAQKQKRILERGCDVIVATPGRLWDLIKADDELATSVRTLRFLVIDEADRMIENGHFAELESIVKLTQRSTAQQGPDDDDPVFQAMATLFEESTAREDMQTFVFSATLSKDLQKNLKRRSRSWKGKGKRSSTLEDLVEKLDFRDENPEVIDLSPEGGVVSSLRESMIESTKDDKDLYLYYFLLRYPGRSIVFVNSIDSIRRLLPLFTLLQLPVFPLHSHLQQKQRLKNLDRFKSNPKGILIATDVAARGLDIPQVDHVVHFNLPRTADAYIHRSGRTARAQNEGFALQLVSPDEKSVQRALMKSLERTHELPDLPIEAGFLPSLRERLRVATEIEKAQHRATKATHDKNWLLEAAEAMDIDIDPSMLDGEDDDPDAPYYKPKKQDRGKGKASVENLKMELKALLQEKLVARGVSIRYPTSGSKVIVDDLIKSTGHGMLLGASTSKAYDQVEKTGKRKLGSGRPGAVKKKKVEGR
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase MAK5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX24/MAK5 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL15_STRPF
Sequence: MKLHELKAAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNVFDDGTEVTPAILKDAGIVRAEKSGVKVLGNGELTKKLTVKAAKFSKSAEAAIIAKGGSIEVI
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: VL1_HPV40
Sequence: MWQLNENQVYLPPPTPVATIVSTDEYVQRTSLYYHAGSARLLTIGHPYFELKKPNGDISVPKVSGHQYRVFRVRLPDPNKFGLSDTSLFNSETQRLVWACVGVEVGRGQPLGVGVSGHPYFNKDEDVENSSAYGTGPGQDSRENVAMDYKQTQLCMLGCTPPIGEYWGKGTPCNASRVTLGDCPVLELKTEVIQDGDMVDTGFGAMDFASLQANKSDVPLDLCTSISKYPDYLGMAAEPYGNSLFFFLRREQMFVRHFFNRAGTTGDSVPTDLYITGTSGRTPIAGSIYYSTPSGSLVTSDSQIFNKPLWIQKAQGHNNGICFGNQLFVTVVDTTRSTNLTLCAATQSPTPTPYNNSNFKEYLRHGEEFDLQFIFQLCVITLNAEVMTYIHAMDPTLLEDWNFKIAPPASASLEDTYRFLTNKAIACQRDAPPKVREDPYKKYKFWDVNLTERFSSQLDQFPLGRKFLMQAGVRAGPRFKSRKRPAPSSSSSSKPVTPKRKKTKR
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: IMP1B_ARATH
Sequence: MTSPSSSFWNTASREAMKSGMFVAKVYCFLHVTTNYLGFMAYAYGPSMIPTLHPSGNMLLAERISKRYQKPSRGDIVVIRSPENPNKTPIKRVVGVEGDCISFVIDPVKSDESQTIVVPKGHVFVQGDYTHNSRDSRNFGPVPYGLIQGRVLWRVWPFQDFGPLGPTPT
What is the function of this protein?
Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space.
What are the official names of this protein?
Mitochondrial ATP-independent inner membrane protease subunit 1b, AtIMP1b.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26 family. IMP1 subfamily.
Protein: PRSA_STRA5
Sequence: MKTRSKLAAGFLTLMSVATLAACSGKTSNGTNVVTMKGDTITVSDFYDQVKTSKAAQQSMLTLILSRVFDTQYGDKVSDKKVSEAYNKTAKGYGNSFSSALSQAGLTPEGYKQQIRTTMLVEYAVKEAAKKELTEANYKEAYKNYTPETSVQVIKLDAEDKAKSVLKDVKADGADFAKIAKEKTTATDKKVEYKFDSAGTTLPKEVMSAAFKLDKNGVSDVVSTVDSTTYKTSYYIIKVTDKTEKKSDWKSYKNRLKEVILKDKTSDRAFQNKVISKALEKANVKIKDKAFAGILSQYATTSGSSSLKK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PQQA_CUPTR
Sequence: MTWTTPAYTELRLGFEITMYIANR
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: MSHB3_CATAD
Sequence: MTLPLDLLDMPFARLGDRLGNPLRLLMVHAHPDDETTTTGATAALYAAETIDVYLVTCTRGERGEILDPEAQRVVDDAADGEQALGELRVRELAGAVTMLGIKGSRFLGGAGRWWDSGMAGEESNTDPRSLVAGDFQEQVDALAAAIREIRPQVLVTYDSRGGYGHPDHIRAHQLSLAAVDRAAETGGESESGGEGGGEGAEAWSVAKVYAAVVPFSILRSVARRLGSNGDSPFAPLAEALANGVPEDLIEIPYGVPDHLVTAQIDARDWLDAKTAAMRSHRSQMAADSWFFKLAASSDGGFGIEHFQLLRGTAGPLDDGFEADLFAGVRAVDDSDCEPDFGWLPEEEPAGGELF
What is the function of this protein?
Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
What are the official names of this protein?
1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase 3, GlcNAc-Ins deacetylase 3, N-acetyl-1-D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 3.
What is the protein family that this protein belongs to?
Belongs to the MshB deacetylase family.