PharMolix/UniProtQA huggingface dataset:
Protein: ARHG5_MOUSE
Sequence: MEAEEPEYGVSTEVPDIEELKTIPEGIMRSSQIPALDPEAQEDRDPSYKWTDGHRPVMNQSKVLRDMGDHTPNSMAIFFKKESSDMETSQEILLAEACNTPDQQEAVIQSLKDRLSRTIAAPELLACAVQEEWLDIPSKLDNRVGAELQSELMSLTLAVSKEKEEEETSPDTSIPRGSWPPCKTHPGETEQTQGSGSELLRQGKQLQLEATQENQGQEGFLQSQEAQGLEEQEGQEVEIQEEGTLNEGICFGGLLGEQEEVEEGFNGNEEEQKQGQIQSYMLLGGQWENEGLSGELEGLNYSERGQENRERRVWVLRDSEEEGQDQESREVEERRVATQYTENQRLVEKSEIVKRKQRDHDQTGKVMPVRDQKEVVDSGDRVQGNGDSGGQTAVEGSRPGEDSKPSLPVASVDPEVLSPGTLFPGISSSVADIPQIQKEPVCEELSPQAPALEPTEWSHQPISPPASFAPEESLDNRTHNSQQEEFRLRKGIEVVSASTSVAPSGTRDSPPFSPPNVFSSTATLSPVSSSVILPEETPTASASADTPHHCGPCETPPLPAKSSRYPCATSDTANPHSPLSSYTGVTQHLRSNSFPGSHRTEQTPDSLGMSLSFSHLELPQRPPKPAIYGSLTPRRNRRSRDGIVFSDSSTALFALKQDSEEFTSNPERPSSPHGSPTWGSPQNSAFAIGSPANVSSPPTVSMDMTIREALLPIPPEKRHSYSHIVERDGLLHEVASTLKRHSHPPPLTLSSGLHRSSKGSFSLVPDSTVARQHRPLPSTPESPNHTQTSIPSRLRYNKPLPPTPDMPEFYHPSISSSYISRMYRPLPPVPIIDPSSEPPPLPPKSRGRSKSIQGGVIHSGGQAKPRPNNQDWTASTLSVGRTSWPPATGRSTESLPLTSRCNNEVSPGLAFSNMTNLLSPSSPTTPWIPDLQRPTTKDESGLTEESEPPVRGSFRRSAPQEEFNNTRRSALGSRKNSEKPLHHQLEKASSWPHRRDPARTSESSSEQVVLGQVPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLISSQLLYQEYSDVVLNKEIQSQQRLDSLAEPHGLSSPRHRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSAQLRGTLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLNHAADFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPICQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLRRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLLHNAQGTQVEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQV
What is the function of this protein?
Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:19713215, PubMed:21525037).  Strongly activates RHOA (PubMed:19713215, PubMed:21525037).  Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (PubMed:19713215).  Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:21525037).  Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (By similarity).  Required for SRC-induced podosome formation (PubMed:21525037).  Involved in positive regulation of immature dendritic cell migration (PubMed:19713215).
What are the official names of this protein?
Rho guanine nucleotide exchange factor 5.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell projection, podosome.
Protein: RS8_CHLAD
Sequence: MSVNDPIGDMLTRIRNACMARHTTVTMPASKMKIAIADILKREGFIRDYTVIDDGKPYKTISITLKYMPDRRPAITGLRRVSKPGLRVYTKRADIPRVRGGLGLSILSTPKGVLADHEAWRARVGGEVLCYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: LPXA_ECOLI
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLP11_ARATH
Sequence: MTRSHCYWFYCIITIYFSFLIHSLASPSLHFCRHDQRDGLLKFRDEFPIFESKSSPWNKTTDCCSWDGVTCDDKSGQVISLDLRSTLLNSSLKTNSSLFRLQYLRHLDLSGCNLHGEIPSSLGNLSRLENLELSSNRLVGEIPYSIGNLKQLRNLSLGDNDLIGEIPSSLGNLSLLLDLDLWNNSLVGEVPASIGNLNELRVMSLDRNSLSGSIPISFTNLTKLSEFRIFFNNFTSLPSDLSGFHNLVTFDISANSFSGHFPKFLFSIPSLAWVSMDRNQFSGPIEFANISSSSKLQNLILTRNKLDGSIPESISKFLNLVLLDVAHNNISGPVPRSMSKLVSLRIFGFSNNKLEGEVPSWLWRLSSTMLSHNSFSSFEKIYSKETMIQVLDLSFNSFRGTFPVWICKLKGLHFLDLSNNLFNGSIPLCLRNFNLTGLILGNNKFSGTLPDIFANNTNLQSLDVSGNQLEGKFPKSLINCKGLHFVNVESNKIKDTFPSWLGSLPSLQVLILRSNDFYGPLYHPSMSIGFQGLRIIDISHNGFSGVLPPNFFSSWREMITLVHGSYEYIEDIQNYSLIYRSMEMVNKGVEMSFERIRQDFRAIDFSENRIYGEIPESIGCLEELRLLNLSGNAFTSDIPRVWENLTKLETLDLSRNKLSGQIPQDLGKLSFLSYMNFSHNRLQGPVPRGTQFQRQRCSSFLDNHRLYGLEDICEETHVPNPTSQPSEDLLDEEEKMFNWVAAAIAYGPGVFCGLVIGYIFTSHHHEWFTEKFGRKKIRVTTSAR
What is the function of this protein?
Involved in the perception of CLV3 and CLV3-like peptides, that act as extracellular signals regulating meristems maintenance.
What are the official names of this protein?
Receptor-like protein 11, AtRLP11.
What is the protein family that this protein belongs to?
Belongs to the RLP family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: END3_AJECN
Sequence: MSEKKIEQWEVERYWEIFSSLSNGQPHLNNAQAATVLRNSRLRDDQLEKVWDLADVDGDGELDFEEFCVAMRLIFDLVNGEYADVPHSLPDWLIPESKAHLVQASRALTGRQPQFERVEEEDDTPGLKDGFDWYMSPGDKSKYEEIYSANRNHRGEITFDSLQPLYDSLAVPDTDIRSAWNLVNPSASSTISKDATLAFLHILNNRHEGYRIPRTVPASLRASFESNKIDYQLDNVRPAQRWGADTDVDTSTGRKAKFGDAYLSRLGVGGRTTYRPQGTDFSNTIQDQEWEKVRLRRELAELEKKLEAADGAMESRKGGGGSVNGGPNWTLIKKEALQLLEYKERELRELREGTGKVKEGESLERLREDVKTVGDQVEGLRAHLAKRNETLTELKDQIREEKRSR
What is the function of this protein?
Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis.  The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton.  Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins.  Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity).
What are the official names of this protein?
Actin cytoskeleton-regulatory complex protein END3, Endocytosis protein 3.
What is the protein family that this protein belongs to?
Belongs to the END3 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, actin patch. Note=Cytoplasmic and cortical actin patches.
Protein: MCL1_CANLF
Sequence: MFGLKRNAVIRTQLYCGGAGLGAGSGGASSSGGRLLASGREATTRREGGGGEAGAVIGGSAGASPPTTLAPDARRVARPSPIGAEGPNVSATPPRLLLLAPPCRASPPEEMEGPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGEASSGPGMDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDAKPLGGSRAASRKALETLQRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVIVHVFSDGVTNWGRIVTLISFGAFVAKHLKSINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
What is the function of this protein?
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation.  Mediates its effects by interactions with a number of other regulators of apoptosis (By similarity).
What are the official names of this protein?
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the Bcl-2 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Cytoplasm. Mitochondrion. Nucleus, nucleoplasm. Note=Cytoplasmic, associated with mitochondria.
Protein: XPT_STAAB
Sequence: MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDITQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
What is the function of this protein?
Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
What are the official names of this protein?
Xanthine phosphoribosyltransferase, XPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP19A_ARATH
Sequence: MATNPKVYFDMTVGGKSAGRIVMELYADTTPETAENFRALCTGERGIGKQGKPLHYKGSSFHRVIPKFMCQGGDFTAGNGTGGESIYGSKFKDENFIKKHTGPGILSMANAGANTNGSQFFICTEKTSWLDGKHVVFGQVVEGLNVVRDIEKVGSDSGRTSKPVVIADCGQIS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Involved in reactive oxygen species production in response to pathogen infection.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP19-1, PPIase CYP19-1, Cyclophilin of 19 kDa 1, Rotamase cyclophilin-3.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLR_STAES
Sequence: MTNILIVEDEQNLARFIELELTHENYTVDIENDGKVGLDKALSKPYDLYILDLMLPNINGLEICRQIRQKTTTPIIIITAKSETYDKVAGLDYGADDYIVKPFDIEELLARIRAVLRRQPDKDVLDINGIIIDKDAFKVTVNGHQLELTKTEYDLLYVLAENRNHVMQREQILDHVWGYNSEVETNVVDVYIRYLRNKLKPFNKEKSIETVRGVGYVIR
What is the function of this protein?
Member of the two-component regulatory system ArlS/ArlR.
What are the official names of this protein?
Response regulator ArlR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_LATSS
Sequence: MRTTYMAKPGEVERKWYVIDATDIALGRLSTVVASILRGKNKPTFTPNVDTGDNIIVINAEKIKLTGRKATDKLYHHHSNHPGGLKTRTAGEIRENNPERLIEMSVKGMLPKNSLGHNQFLKLHVYAGGEHKHQAQNPEVLDITDII
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL19_SHESH
Sequence: MNNIIKMLNEEQMKQDVPEFGAGDTVVVKVRVVEGGKERLQAFEGVVIAKRNRGVHSAFTVRKISNGEGVERAFQIHSPIISSIEVKRRGRVRRAKLYYLRERSGKSARIREKLATK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: K1549_MOUSE
Sequence: MEREPRARVALVPERCGRGPSSRHRRPGLLLPGLWLLLLAGPASCAPDDLSLAQHSHPVRPSDFLPERSILHSAAQVTLSETVPRSQPSISALVLSSPSATAFDTAFLSQRQQTQSTAEPSFFEANYGSVTSNEVALDDEEMDNFLPDAHWTSSRGVSPMRYITPSPPEPPQEMLEPGTTPSLPTISLPDEVLSGCQNTVQQATVYVEPSTYFGTSWSAFLTSEGIIPTPSRNSVLHPIEIHSQLSSKALPETVASVTEGAENLLFSSRISVSQPSGNGMTQQPSVPLWEVSQPLVGVLATSSDRYPNETTAWIEHPEEAIALRAHPGITTSPTDPTFSSQPSALFSTPLSSVSFATQLPGVSEDSFLSSEARGALESWHSSPVPSFTDHPYVLSPESSLRPHTGCVSCVVSSFQQELARSLTEKDMGSGDRLETLSTASVEASHVSPLSSVGTDLSELEEPQEFNTLFPSRPVFSFSSRPVGLWKASMDVSPEVDVSGIAITQVYPSHGRLSTPSSLDSTFGFSVTSDLVMSSSMIHLLSSVIPSTHFDSSFSLTANQNSPSFPAGKPSLLTSPSLVPSAQSSAFSHGAPTSSLELQSGSRLDFTSGFYSTPPLDFSTPAPSRSDELAFPSLMSSDPSTFFSQTFSTMAETFSLSNSMNLQSPQLSVLNPTSLEPSQPQSSADLLLNTVTVLPSPPERPPLSSSPSDSLEFTEVSRVSLRESHVHLTSAFSETTSAFEFSPIPHESTISTLVPSSSEPSLGIYAAGTHLTSLPTTVFHLTPILTESSPFSTLTPSDGSVRVTDHHTPVLPTPSSVIPSSTESISDPYLSASSSLVSEVSPSPPPTKPVMGSSLTSTDFPPSTSPELSTSLELSMPSASTAPGDTVDSALNSEPMSQNPQGNSVPPPQPSLGPATTSTLEATVGTPALATAKPPYVCDITVPDVYLITTVLARRAVQEYIITSIKEVLRIHFNRAVELKVYELFTDFTFLVTSGPFVYTAISVINVLINSKLVRGQTPLILSVKPSFLVPDPRFQVQTVLQFVPPSVDTGFCNFTQSIEKGLVTALFEVRKHQGTYNLTVQIVNVTIASSRVAPRRGPVNIIFAVKGSQGFLNGSEVSDLLRNLTVVEFSFYLGYPVLQIAEPFQYPQLNLSQLLKSSWVRTVLLGVVEKQLHNEVFPAEMERKLAQLLSEVPTRRRVWRRATVAAGNSVVQVVNVSRLEGDDNPVQLIYFVENQDGERLSAVKSSDLINKVDLQRAAIILGYRIQGVIAQPVDRVKRPSPESQSNNLWVVVGVVIPVLVVTVIVVILYWKLCRTDKLDFQPDTVANIQQRQKLQIPSVKGFDFAKQHLGQHNKDDILIIHEPAPLPGPVKDHTTPSENGDVPSPKSKLPSKNIRLRGRVSPSDADSTVSEESSERDAGEKAPAAAPENKALRAPQSGAPLPSSGNEQHSSASIFEHVDRVSRTSEASRRVPSKIQLIAMQPIPAPPAQHPVLADRVAETNKINKEIQSALRHKSEIEHHRNKIRLRAKRRGHYEFPVVDDLSSGDTKERHRVYRRAQMQIDKILDPAASVPSVFIEPRKSSRMKRSPKPRRKHQVNGCPADAEKDRLITTDSDGTYKRPPGVHNSAYIGCPSDPDLPADVQTPSSTELGRYPGLPFSASQYIPPQPSIEEARQTMHSLLDDAFALVAPSSQPTNAMGAGTGVPASLPVNSTPSREERRATQWGSFYSPAQTANNPCSRYEDYGMTPPSGPLPSRPSFGPGLLPSSELVPPEPPQPQSSTDAPYAARGIYSEEMPSVARPRPVGGTTGSQIQHLTQVGIASRIGAQPVEIPAGRGSQYGGPGWPVYGEEEAGRREATHMLGHQEYSSSPLFQVPRTSGREPSAPPGNLAHRGLQGPGLGYPTSSTEDLQPGHSSASLIKAIREELLRLSQKQGSVQNFHS
What is the function of this protein?
May play a role in photoreceptor function.
What are the official names of this protein?
UPF0606 protein KIAA1549.
What is the protein family that this protein belongs to?
Belongs to the UPF0606 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, cilium. Note=In the retinal photoreceptor cells, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment.
Protein: PSEG_CAMJE
Sequence: MKVLFRSDSSSQIGFGHIKRDLVLAKQYSDVSFACLPLEGSLIDEIPYPVYELSSESIYELINLIKEEKFELLIIDHYGISVDDEKLIKLETGVKILSFDDEIKPHHCDILLNVNAYAKASDYEGLVPFKCEVRCGFSYALIREEFYQEAKENREKKYDFFICMGGTDIKNLSLQIASELPKTKIISIATSSSNPNLKKLQKFAKLHNNIRLFIDHENIAKLMNESNKLIISASSLVNEALLLKANFKAICYVKNQESTATWLAKKGYEVEYKY
What is the function of this protein?
Nucleotide sugar hydrolase that catalyzes the fourth step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin.  Mediates the removal of UDP from C-1 of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose forming 2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose.
What are the official names of this protein?
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase, Pseudaminic acid biosynthesis protein G.
What is the protein family that this protein belongs to?
Belongs to the PseG family.
Protein: ADDB_BACAH
Sequence: MSLRFVIGRAGSGKSTLCLHEVQEELKQRPRGETILYLVPEQMTFQTQQALIGSEDVRGSIRAQVFSFSRLAWKVLQEVGGASRLHIDEAGVHMLLRKIVESRKDGLSVFQKAAEQNGFFEHLGSMIAEFKRYNVTPSNVYEMWQQLDAHSSSAEQKLLANKVYDLQLLYDDFERALIGKYLDSEDYLQLLVENLPQSEYVKGAEVYIDGFHSFSPQELEIVRQLMICGARVTITLTIDEKTLAQPVNELDLFYETTLTYEKIKQVAREEKIEIEKTIPLMEQPRFHSPALAHLEMHYEARPNEKFHGEASVTIHTAANLRAEVEGVAREIRRLVAEENYRYRDIAVLLRNGESYYDVMRTLFTDYNIPHFIDEKRPMSHHPLVECIRSALEIISGNWRYDAVFRCVKTELLYPLDVRKETMREEMDEFENYCLAYGVQGKRWTSEDPWMYRRYRSLDDTNGMITDSEREMEEKINRLRDVVRTPVIRMQKRLKRAGTVMQMCEAVYLFLEELDVPKKLEALRIRAEESGDFLFATDHEQVWEEVMSLLDTFVEMLGEEKMSLSMFTDVMSTGLEALQFANIPPSLDQVLIANIDRSRLSNVKATFVIGVNEGVIPAAPMDEGMLSDEERDVLSAAGIELAPTTRQTLLEEQFVMYQMVTRATEKLYISCPLADEEGKTLLASSFIKKIKRMFPNVKDTFITNDVNDLSRSEQISYVATPEVTLSYVMQQLQTWKRYGFEGNLDFWWDVYNFYVTSDEWKQKSSRVLSSLFYRNRAQKLSTAVSRDLYGDKIKGSVSRMELFNRCAYAHFAQHGLSLRERDIFKLDAPDIGELFHAALKRIADRLLRENRTWADLSIKECEHLSTVVIEEIAPLLQRQILLSSNRHFYLKQKLQQIIFRTSIILREHAKSSGFVPVDLEVPFGMGGTGSLPPMEFSLPNGVKMEVVGRIDRVDKAEDENGTFLRIIDYKSSSKSLDLTEVYYGLALQMLTYLDVVTSNAQTWMKKGHAASPAGVLYFHIHNPIVEVKGDASEAEIEKEILKKFKMKGLVLGDADVVRLMDNKLSTGSSDIISAGLKKDGSFSARSSIASEQEFNVLQKYVHHTFKNIGKDITEGVIDIAPYKKGNKAACTFCNFKSVCQFDESLEDNQFRTLKDMKDSEAMEKIREEVGGE
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: SUB2_TRITO
Sequence: MQLLNFGLLLLPFVAGDLAPQPEPLLAGPSDVVPGQYIVTLKEGLTSAQIRDHKKWVSSVHRANLEGFAAGASGVETEGIMKHFHIHDLNMYSGGFDEKTVEDLSRNPYVKSVHPDQHVYLAKTVTQRQARWGLGYMSSKGKPVPLHSTLVDYSYDDKAGEGVWAYVLDTGINVNHVEFEGRAILGHNAIPNKPHTDEFGHGTYVAGIIAGKTYGVAKKANVVSAKAFDTGSSTYNYILETYDWIVRNITDSNRKNKAVINFSISGAKYQPFDDAVEKAFKAGIATVVAAGNDGKDAKNNTPASSPNAITVGAVRWENTRPSFSNYGKIVDIWAPGELIKSCWKGGNNATSTQSGTSAASPHVAGLVAYLMSTENLPSPSAVTARVLNLTIPNLVKDAKDSPNRVVYNGIQERKFTLPKYF
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y2077_DICDI
Sequence: MFKSRIETGGFQFQVHGDDESAMDDEFIDDDDDQQVVEPVTDN
What are the official names of this protein?
Uncharacterized protein DDB_G0268276.
Protein: SYI_BURCJ
Sequence: MSNKKADSKPQAKYPVNLLDTPFPMRGDLPKREPQWVKEWEERGIYDKIRAASQGRPKFILHDGPPYANGDIHLGHAVNKILKDIVVKSRNMAGFDAPYVPGWDCHGMPIEIQIEKQFGKSLPAAEVMSKARAYATEQIEKQKVGFKRLGVLGDWANPYKTMNFVNEAEEIRALGKIIEKGYVYRGLKPVNWCFDCGSALAEAEVEYKDRTDPTIDVMFAFAEPEKTAQAFGLPALPRADGGIVIWTTTPWTIPANQALNLHPEIVYALVDTERGLLIIAEERVEACMSDFKLTGRIIATTPGVKLANLRFHHPLASAHPGYKRTAPVYLGDYVTTDTGTGVVHSSPAYGIEDFMSCKAHGMTDSDFINPVMGDGRYIESLPLFGGLSIWDANPKIVDALNAAGSLLRSEKYTHSYMHCWRHKTPIIYRATSQWFAGMDVTPRDGGKTLRETALEGVDATAFYPSWGKQRLFSMIANRPDWTLSRQRQWGVPMAFFVHKETGELHPRTLELLEEVAKRVEQSGIEAWQSLDPRELIGDDANLYEKNRDTLDVWFDSGTTHWHVLRGSHKDQLQFPADLYLEGSDQHRGWFHSSLLTASMIDGRAPYKGLLTHGFTVDGEGRKMSKSLGNGIDPHEVANRLGAEIIRLWIASTDYSGELAISEEILKRVTEGYRRIRNTLRFLLANLSDFDFAQHAVPVDEWLEIDRYAVAFSQQLQTELLGHYEKYEFHPVVAKLQTYCSEDLGGFYLDVLKDRLYTSAADSRARRSAQTALYHLTHGLLRVLAPFLSFTAEEAWKVFQPASDTIFTETYYAYPEVAGSAALIDKWALLRDVRGNVTKALEEARTANRIGSSLQAEVTVHASGARYDALTSLGDDLKFVLITSAATVVKVDDEAQESVDVAASKYQKCERCWHYREDVGAHAEHPTLCGRCFSNLFENGEIRSAA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y681_STAAM
Sequence: MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYINAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD
What are the official names of this protein?
UPF0178 protein SAV0681.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: CYB_VESSI
Sequence: MTNIRKSHPLIKIINQSFIDLPAPSNISSWWNFGSLLGICLALQIVTGLFLAMHYTSDTDTAFNSVSHMCRDVNYGWVLRYLHANGASMFFICLYLHVGRGIYYGSYMFKETWNMGVILLFAVMATAFLGYVLPWGQMSFWGATVITNLLSAIPYVGTDLVAWIWGGFAVDKATLTRFFAFHFLLPFIIAALVMVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGLFVMILVLSSLVMFSPDMLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILVLFIFPLLHTSKQRSMAFRPFSQCLFWLLIANLLTLTWIGGQPVEQPYIIIGQLASILYFLIIIVIMPLTSLMENHLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: 3L22_NAJNA
Sequence: IRCFITPDITSKDCPNGHVCYTKTWCDGFCSSRGKRVDLGCAATCPTVRTGVDIQCCSTDDCDPFPTRKRP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 2, Toxin B.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC1_LACLA
Sequence: MKKKFSLIAMAGAALLLLTACGTTAVTSSSTNLWDQIVYGFAQVIRFLSFGGLTGVGIILFTIVIRAALLPLMNIQIKSSQRMQEIQPEIKKIQAKYPSKDMESRRLMNEEIQKLYAENKVNPYMGCLPLVVQMPVLWALYQALSRVDFLKHGTFLWFEIGAKDPTFILPILAAVFTFLSSYLMMKSAPERNAMTTSMTYIMPIFILIMGVNFAAGIALYWVISNAFQVFQTMLLANPYKIIAAREAKVQVEKDKIKAREKALKKARKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC 1, Foldase YidC 1, Membrane integrase YidC 1, Membrane protein YidC 1.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PYRB_STAAN
Sequence: MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLFFENSTRTKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIRHPFNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNVLICGDIKNSRVARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVIETVDIVMLLRIQHERHGLAEETRFAADDYHQKHGLNEVRYNKLQEHAIVMHPAPVNRGVEIQSDLVEASKSRIFKQMENGVYLRMAVIDELLK
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: ATPG_BACP3
Sequence: MKPLASLRDIKTRINATKKTSQITKAMEMVLTSKLNRAEKREIVRPYMEKIQEVVANVALAARASHPMLVSRPVKKTGYLVITSDRGLAGAYNSNVLRLVYQTIQKRHASPDEYAIIVIGRVGLSFFRKRNMPVILDITRLPDQPSFADIKEIARKTVGLFADGTFDELYMYYNHYVSAIQQEVTERKLLPLTDLAENKQRTVYEFEPSQEEILDVLLPQYAESLIYGALLDAKASEHAARMTAMKNATDNANELIRTLTLSYNRARQAAITQEITEIVAGANALQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPOA_MYCS2
Sequence: MLISQRPTLSEETVAENRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAVTSIRIDGVLHEFTTVPGVKEDVTDIILNLKGLVVSSDDDEPVTMYLRKQGPGVVTAGDIVPPAGVTVHNPDMHIATLNDKGKLEVELVVERGRGYVPAVQNKASGAEIGRIPVDSIYSPVLKVTYKVEATRVEQRTDFDKLIIDVETKNSISPRDALASAGGTLVELFGLARELNADSEHIEIGPSPAEADHIASFALPIDDLDLTVRSYNCLKREGVHTVGELVARTESDLLDIRNFGQKSIDEVKIKLHQLGLSLKDSPATFDPSEVAGYDAATGTWTSDAGYDLDDNQDYAETEQL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.