PharMolix/UniProtQA huggingface dataset:
Protein: DLTA_STRPZ
Sequence: MIKDMIASIEQFAQTQADFPVYDCLGERRTYGQLKRDSDSIAAFIDSLALLAKSPVLVFGAQTYDMLATFVALTKSGHAYIPVDVHSAPERILAIIEIAKPSLIIAIEEFPLTIEGISLVSLSEIESAKLAEMPYERTHSVKGDDNYYIIFTSGTTGQPKGVQISHDNLLSFTNWMIEDAAFDVPKQPQMLAQPPYSFDLSVMYWAPTLALGGTLFALPKELVADFKQLFTTIAQLPVGIWTSTPSFADMAMLSDDFCQAKMPALTHFYFDGEELTVSTARKLFERFPSAKIINAYGPTEATVALSAIEITREMVDNYTRLPIGYPKPDSPTYIIDEDGKELASGEQGEIIVTGPAVSKGYLNNPEKTAEAFFTFKGQPAYHTGDIGSLTEDNILLYGGRLDFQIKYAGYRIELEDVSQQLNQSPMVASAVAVPRYNKEHKVQNLLAYIVVKDGVKERFDRELELTKAIKASVKDHMMSYMMPSKFLYRDSLPLTPNGKIDIKTLINEVNNR
What is the function of this protein?
Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC.  In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanine--D-alanyl carrier protein ligase, DCL, D-alanine--poly(phosphoribitol) ligase subunit 1, D-alanine-activating enzyme, DAE.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ABRB_ABRPR
Sequence: QDQVIKFTTEGATSQSYKQFIEALRQRLTGGLIHGIPVLPDPTTLQERNRYISVELSNSDTESIEAGIDVSNAYVVAYRAGNRSYFLRDAPTSASRYLFTGTQQYSLRFNGSYIDLERLARQTRQQIPLGLQALRHAISFLQSGTDDQEIARTLIVIIQMASEAARYRFISYRVGVSIRTNTAFQPDAAMISLENNWDNLSGGVQQSVQDTFPNAVTLRSVNNQPVIVDSLTHQSVAVLALMLFVCNPPNANQSPLLIRSIVEKSKICSSRYEPTVRIGGRNGMCVDVYDDGYHNGNRIIAWKCKDRLEENQLWTLKSDKTIRSNGKCLTTEGYAPGNYVMIYDCTSAVAEATYWEIWDNGTIINPKSALVLSAESSSMGGTLTVQTNEYLMRQGWRTGNNTSPFVTSISGYSDLCMQAQGSNVWLAYCDNNKKEQQWALYTDGSIRSVQNTNNCLTSKDHKQGSPIVLMACSNGWASQRWLFRNDGSIYNLHDDMVMDVKRSDPSLKEIILHPYHGKPNQIWLTLF
What is the function of this protein?
The B chain is a galactose-specific lectin that facilitates the binding of abrin to the cell membrane that precedes endocytosis.
What are the official names of this protein?
Abrin-b.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ribosome-inactivating protein family. Type 2 RIP subfamily.
Protein: FOLD_BRUMB
Sequence: MAQLIDGKKLAEDVVSTVKTETEKLVAATGVVPGIAVVIVGEDPASQVYVASKSRKAKECGFHSVQHDLPETASEQELLNLIEGLNNDPAIHGILVQLPLPGHIDSGRVIQTIAPEKDVDGFHFINVGKLGTGEVETAFVPCTPAGAMIMIERVHGRDLSGLNAVVIGRSNIVGKPMFNLLLAANATVTVAHSRTKDLPAIARNADILVAAVGRPQMVKGDWVKPGATVIDVGINRIPAPERGEGKTRLVGDVDFAEAEKVAGAITPVPGGVGPMTIAMLMANTLTAACRSAGMKKPVF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: RIMM_STRM5
Sequence: MKDNERRILLGRIVGAFGVRGEIKLESWTEPRSAIFRYQPWILRSPNGQESTLEGARGRDSGKHLVARFPGIEDRDTVEAMHGTEVYVARSALPPPNADEYYWVDLEGLDVKTTEGVALGQVSHLFSTGANDVVVVRGDRERMIPFVLPEFVKSVDFEANLVVVDWDPEF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNA_PYRFU
Sequence: MNISVSMNKFDSKIKFVQLVFVDINGMPKGMEIPASRLEEAVTDGISFDGSSVPGFQGIEDSDLVFKADPDTYVEVPWDNVARVYGFIYKDNKPYGADPRGILKRALEELEKEGYKAYIGPEPEFYLFKKNGTWELEIPDVGGYFDILTLDKARDIRREIAEYMPSFGLIPEVLHHEVGKAQHEIDFRYDEALKTADNIVSFKYITKAVAEMHGLYATFMPKPLFGFPGNGMHLHISLWKDGENVFMGEEGLSEIALHFIGGILKHAKALTAVTNPTVNSYKRLVPSYEAPVYISWGYRNRSALIRVPAFWGKGARIEYRCPDPSANPYFAFAAVLKAGLDGIKHKIDPFAYVEENVYEMSEEKRKELGIETLPGSLGEALEELEKDKVVKEALGDAYKNFINYKWKEWESYLEYLEEKHMPKDTKKVTEWELERYFFL
What is the function of this protein?
Probably involved in nitrogen metabolism via ammonium assimilation.  Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.
What are the official names of this protein?
Glutamine synthetase, GS, Glutamate--ammonia ligase, Glutamine synthetase I alpha, GSI alpha.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSPZ_SHIFL
Sequence: MISPIKNIKNVFPINTANTEYIVRNIYPRVEHGYFNESPNIYDKKYISGITRSMAQLKIEEFINEKSRRLNYMKTMYSPCPEDFQPISRDEASIPEGSWLTVISGKRPMGQFSVDSLYHPDLHALCELPEISCKIFPKENSDFLYIIVVFRNDSPQGELRANRFIELYDIKREIMQVLRDESPELKSIKSEIIIAREMGELFSYASEEIDSYIKQMNDRFSQIKARMSVT
What is the function of this protein?
Cysteine methyltransferase effector that inhibits host cell NF-kappa-B activation by preventing nuclear translocation of host protein RELA/p65 (PubMed:20485572).  Acts by mediating cysteine methylation of host proteins TAB2 and TAB3: methylation of a conserved cysteine residue of the RanBP2-type zinc finger (NZF) of TAB2 and TAB3 disrupts zinc-binding, thereby inactivating the ubiquitin chain-binding activity of TAB2 and TAB3, leading to NF-kappa-B inactivation (PubMed:27445336).  Also mediates cysteine methylation of host protein ZRANB3, inactivating its ability to bind ubiquitin chains (PubMed:27445336).
What are the official names of this protein?
Cysteine S-methyltransferase OspZ, Effector protein OspZ.
What is the protein family that this protein belongs to?
Belongs to the NleE/OspZ family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Host nucleus. Note=Secreted via the type III secretion system (TTSS). Mainly localizes in the cytoplasm of the infected cells, and occasionaly in the host nucleus.
Protein: SYGB_DESRM
Sequence: MAKDFLLEVGIEEMPARFLGPALTQLKEQTVKTLQELRIEYADIQTYGTPRRLVLYIKDLAENQAALEKEVKGPAKKAAFDAAGNPTKAILGFTRSQGVSMEDLVVRSIGQVEYLYALKREEGRPTAQVLAEICPGLIAGLHFPKPMRWGELELRFARPIRWLLALFGEAVVPFELANLQSNRFTYGHRFLSTGDLSIANPEDYFTKIRGAYVLIDPAERKELIWQQVQELATAEGGVVEKDEDLLDEITNILEWPTALCGTFDEDYLKLPGAVLVTPMREHQRYFPVVSNEGKLLNKFIAVRNGTRAYIEIVTAGNEKVLRARLADAAFFFEEDLKQPLASKVNGLQKVVFLEGLGSIADKVDRIGAMADHLAETLGANEEQRENIQRGALLAKADLITNMVYEFPELQGEMGREYALRNGEAPEVAEAIFEHYLPRFAGDLLPETLAGSVLSVADKMDSIVGCFAIGIQPTGSQDPYALRRQALGICHMLIEGNIHLSLRELVQWAYQGYHEGVELKQDLNQVITEIEEFFKQRLKGILNDRGLSYDTVDAVLTAGFDDIADVVDRGMALAAFRELPAFAALMTAFNRANNLAKHATTTQVQEVHLEHSAEQELYGLLTKLEGEVRPLLEQKNYALALQKIATIQSPLDTFFESVMVMVEDEAVKTNRLALLKKLVGLSMNVADFSKIVVETK
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5279_ARATH
Sequence: MAANDVPCCETMFWVYLLVCVALVVFAGLMSGLTLGLMSLSIVELEVMIKAGEPHDRKNAEKILPLVKNQHLLLCTLLIGNALAMEALPIFVDSLLPAWGAILISVTLILAFGEIIPQAVCSRYGLSIGAKLSFLVRLIIIVFFPLSYPISKLLDLLLGKRHSTLLGRAELKSLVYMHGNEAGKGGELTHDETTIISGALDMSQKSAKDAMTPVSQIFSLDINFKLDEKTMGLIASAGHSRIPIYSVNPNVIIGFILVKNLIKVRPEDETSIRDLPIRRMPKVDLNLPLYDILNIFQTGRSHMAAVVGTKNHTNTNTPVHEKSINGSPNKDANVFLSIPALNSSETSHQSPIRYIDSISDEDEEVIGIITLEDVMEELIQEEIYDETDQYVELHKRITINMPMSGNSPETATWASELASPISPYRSSLLSPSIMISTLLRSPINSPYRHSLLLRPTLHASPPAQSPSILSPDSNNERYYYLSPSRVLRKSYEKLSRSNGS
What are the official names of this protein?
DUF21 domain-containing protein At5g52790, CBS domain-containing protein CBSDUF5.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LEPA_XANP2
Sequence: MTASAQKNIRNFSIVAHIDHGKSTLADRLIQITGGLTEREMTDQVLDSMDIERERGITIKAQTVRLSYKAKDGETYILNLIDTPGHVDFAYEVNRSLAAVEGSLLVVDASQGVEAQTLANVYQAIDNNHDIVPVLNKVDLPAAEPEKVKAQIEDVIGLDASDAIGISAKTGLNVDQVLEAIVTRLPPPMGDRAAPLKALLVDSWYDTYLGVVVLVRIIDGVLKKGQRIKMMGSGAVNDVDRVGVFTPKMVAMAELGPGEIGFLTGSIKEVADTRVGDTITEDKRPCADMLPGFKPAQPVVFCGLFPVDAAQFEDLRAAMGKLRLNDASFSYEMETSAALGFGFRCGFLGLLHLEIIQERLEREFNLDLIATAPSVIYEIQMTDGSVIDLHNPADMPDVVKIEEIREPWIRATILTPDEYLGSVLKLCQDRRGTQIELTYVGARAMVTYDLPLNEVVFDFYDRLKSISKGYASFDYQITEYRAGDLVKMSILVNSEPVDALSMLVHRARADARGRVMCEKLKDLIPQHLFNIPIQAAIGAKIIARETIKALRKDVTAKCYGGDISRKRKLLDKQKEGKKKMRQFGKVEIPQEAFIAALKMDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y1304_LISMO
Sequence: MLEKAKIDRINELSKKKKAGTLTSAEKVEQDKLRKEYIKSFRTHMKGTIENTTIIDPNGKDVTPHKVKQLRKNKY
What are the official names of this protein?
UPF0291 protein lmo1304.
What is the protein family that this protein belongs to?
Belongs to the UPF0291 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPM1N_HUMAN
Sequence: MAVLARQLQRLLWTACKKKEREKEGREEEEEEEAGRRAPEGPRSLLTAPRRAQRPHGGAEASGGLRFGASAAQGWRARMEDAHCTWLSLPGLPPGWALFAVLDGHGGARAARFGARHLPGHVLQELGPEPSEPEGVREALRRAFLSADERLRSLWPRVETGGCTAVVLLVSPRFLYLAHCGDSRAVLSRAGAVAFSTEDHRPLRPRERERIHAAGGTIRRRRVEGSLAVSRALGDFTYKEAPGRPPELQLVSAEPEVAALARQAEDEFMLLASDGVWDTVSGAALAGLVASRLRLGLAPELLCAQLLDTCLCKGSLDNMTCILVCFPGAPRPSEEAIRRELALDAALGCRIAELCASAQKPPSLNTVFRTLASEDIPDLPPGGGLDCKATVIAEVYSQICQVSEECGEKGQDGAGKSNPTHLGSALDMEA
What are the official names of this protein?
Probable protein phosphatase 1N.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: RL20_ECO55
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: KTHY_NEIG2
Sequence: MKPQFITLDGIDGAGKSTNLAVIKAWFERRGLPVLFTREPGGTPVGEALREILLNPETKAGLRAETLMMFAARMQHIEEVILPALSDGIHVVSDRFTDATFAYQGGGRGMPSEDIEILEHWVQGGLRPDLTLLLDVPLEVSMARIGQAREKDRFEQEQADFFMRVRGVYLDRAAACPERYAVIDSNRSLDEVRNSIEKVLDGHFGC
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: ARGR_STRP8
Sequence: MNKKETRHQLIRSLISETTIHTQQELQERLQKNGITITQATLSRDMKELNLVKVTSGNDTHYEALAISQTRWEHRLRFYMEDALVMLKIVQHQIILKTLPGLAQSFGSILDAMQIPEIVATVCGDDTCLIVCEDNEQAKACYETLSHYTPPFFFSNK
What is the function of this protein?
Regulates the transcription of the arc operon, involved in arginine catabolism.
What are the official names of this protein?
Arginine regulator.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTA1_ANAVA
Sequence: MTSFELESPIEIKTDPTDLDQESDSFVQEISRFNKALEQRFRDKMRLHESLSRKIVSFQANKSKPQYRWFKYKEAFSVDLVNQLIFEYEKKSFERILDPFAGAGTMLFACSDAGIQADGIEVLPIGQEIIEVRKIIQRQFRREDFLRLIEWYKQKPWNQHNNRKYLNRLRITDGAYPPETEASIERFLFSIEKENILVKQVLRFALLCILESISYTRKDGQYLRWDKRAFRKSGSDKFDKGKILDFDEAITEQIKLILNDSFDLISNTLFCYGTQRSGINLFNASCLKILPEFEQDFYDCIITSPPYCNRYDYTRTYALELALLGVGERDIVQLRQDMLSCTVENKEKSLIHNWQEALRILDKQELLQSILRFLERELERKKLNNNGIPRMIKGYFYEMACVIIECFRVLKNGSPLFMVNDNVRYAGIDISVDLILSNIAEEIGFNVEKILVLPTGKGNSSQQMGTHGRKTLRKCVYVWRKP
What is the function of this protein?
An alpha subtype methylase that recognizes the double-stranded sequence 5'-CYCGRG-3', methylates C-1 on both strands, and protects the DNA from cleavage by the AvaI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.AvaI, M.AvaI, Modification methylase AvaI, N(4)- cytosine-specific methyltransferase AvaI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.
Protein: PCP_VIBPA
Sequence: MKKVLITGFEPFGGDAINPALEAVKRLEETSLDGGIIVTCQVPVTRFESISAVIDAIEAYQPDCVITVGQAAGRAAITPERVAINVDDFRIPDNGGNQPIDEPIIEQGPDAYFSSLPIKRIAQTLHESGIPCQVSNSAGTFVCNHLFYGVQHYLRDKSIRHGFVHIPLLPEQATDGNHPSMSLDMIVAGLKLVAQVVIDHESDVVVSGGQIC
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_BRUME
Sequence: MALKHFNPITPGQRQLVIVDRSELYKGKPVKSLTEGLSKKGGRNNTGRITVRFQGGGHKRSYRFIDFKRRKLDVVGTVERLEYDPNRTAFIALIRYTDGELAYILAPQRLAVGDQVVAGNSVDVKPGNAMPLSSMPVGTIIHNVELMPGKGGQIARSAGTYAQLVGRDQGMAILRLNSGEQRLVSGACFASVGAVSNPDHGNINDGKAGRSVWRGKRPHVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGKKTRSNKATDKFIMRSRHQRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CNR1B_TAKRU
Sequence: MKLALHRIAGATMAALTTEVQYLGSNDASYEDPQADAALMKSRFNFEKPYSASSSLHRLIPGNKELIYGGLSTILPTNASDFPLSNGSGEATQCGEDIVDNMECFMILTPAQQLVIVILAITLGTFTVLENFVVLCVILHSHTLRSRPSYHFIGSLAVADLIGSIIFVYSFLDFHVLHRKDSPSIFLFKLAGVIASFTASVGSLFLTAIDRYVSIHRPMAYKRIITKTKAVIAFSVMWAISIEFSLLPLLGWNCKRLHSVCSDIFPLIDEKYLMFWIGMTTVLLLFIIYAYMFILWKSHHHAVRMLSRSSQRSIIVYTSEGTKVQTVRPEQARMDLRLAKTLVLILVALIICWGPLLAIMVYDLFGRVNDFIKTVFAFCSMLCLLNSTINPVIYAMRSKDLRRAFVNICHMCRGTTQSLDSSAESDWNSRSVRSTGGRAGKDRSVGGKPQVKVAQVTVSGVTASSPAEAV
What is the function of this protein?
G-protein coupled receptor for cannabinoids (By similarity).  Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues (By similarity).  Regulates cellular respiration and energy production in response to cannabinoids (By similarity).  Signaling typically involves reduction in cyclic AMP (By similarity).
What are the official names of this protein?
Cannabinoid receptor type 1B.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Mitochondrion outer membrane. Cell projection, axon. Presynapse. Note=Unexpectedly, in the mitochondria, the C-terminus is located in the mitochondrial intermembrane space, a compartment topologically considered as extracellular. In canonical seven-transmembrane G-protein coupled receptors, the C-terminus is cytosolic.
Protein: VACHA_DANRE
Sequence: MATEESGGLAQTAAVKLSEMGERTKQLGNAIQDPERQRRIILVIVCVALLLDNMLYMVIVPIVPDYLAHLESESEQAHVKGNSSINITQNENFDLQIGVLFASKAILQLLVNPLTGTFIDRVGYDIPLLIGLSIMFVSTCIFAFAENYATLFMARSLQGLGSAFADTSGIAMIADKYAEESERSRALGIALAFISFGSLAAPPFGGVLYEFAGKRFPFIALACVCLADGILCLTVLKPFSSRTRENMPVGTPIYKLMIDPYIAVVAGALTTCNIPLAFLEPTIANWMEETMNASQWQIGITWLPAFFPHILGVYLTVKLAAKYPHLQWFYGALGMVIIGASSCIVPACKNFEQLIIPLCGVCFGIALVDTALLPTLAFLVDVRHVSVYGSVYAIADISYCVAYALGPIVAGKIVHDLGFVQLNLGMGLANVLYAPALLLLRNVSLMKPSHSERNMLLEEGATGLYDTIRMEERQRKKHGYSSSGNCVPIDENGTFAGQSKSFSEEETSEPEYI
What is the function of this protein?
Involved in acetylcholine transport into synaptic vesicles.
What are the official names of this protein?
Probable vesicular acetylcholine transporter-A, VAChT-A, Solute carrier family 18 member 3-A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Vesicular transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PUR7_COPPD
Sequence: MEKLDLLYEGKAKRVYKTDDPRYYIIEYKDEATAFDGKKKGIIQGKGTVNNKVSAVFFQLLEENGVPTHFVELLSPTEMLVKRVEIIPLEVIVRNYAAGSISRRLGLEEGIKFDQPIVEFCYKNDELGDPMVNNYHILAMKLANEEEINALTQQALRINQILSQFLLGKNIILVDFKLEFGRTDEGDIVLADEISPDTCRFWDSATMEKLDKDRFRRDMGGVEEAYMEIARRLGCV
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: DAPE_SALPC
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALMIERLRKIGFTIEHMDFGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARNERLDYCLVGEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDRGNDFFPATSMQVANIQAGTGSNNVIPGELFVQFNFRFSTELTDEIIKERVHALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: TM14C_MOUSE
Sequence: MQKDSGPLMPLHYFGFGYAALVATGGIIGYAKAGSVPSLAAGLFFGGLAGLGAYQLSQDPRNVWVFLATSGTLAGIMGMRFYNSGKFMPAGLIAGASLLMVAKVGISLLSSPHP
What is the function of this protein?
Required for normal heme biosynthesis.
What are the official names of this protein?
Transmembrane protein 14C.
What is the protein family that this protein belongs to?
Belongs to the TMEM14 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: VGH_BPST1
Sequence: MLGSIIGGIGSSLLGGLASGGISSLLNKMFSKMPEHAASSAGLTNGQGTIGMDTDAGIQSVIQGSNVPPAGQLPASNTSGVMADAGNMIRNAGRALLDGTIQA
What is the function of this protein?
Minor spike component of the viral shell.  Involved in the ejection of the phage DNA in the host and is injected with the DNA in the periplasmic space of the host.  Involved in the determination of the phage host-range (By similarity).
What are the official names of this protein?
Minor spike protein, H protein, Pilot protein.
What are the subcellular locations of this protein?
Virion.
Protein: NSP5_ROTHJ
Sequence: MSLSIDVTSLPSISSSIYKNESSSTTSTLSGKSIGRSEQYISPDAEAFSKYMLSKSPEDIGPSDSASNDPLTSFSNRSNAVKTNADAGVSMDSSTQSRPSSNVGCDQVDFSFNKGIKVSANLDSSVSISTNVKKEKSKNDHRSRKHYPKIEAESDSDDYVLDDSDSDDGKCKNCKYKRKYFALRMRMKRVAMQLIEDL
What is the function of this protein?
Plays an essential role in the viral genome replication.  Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place.  Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories.
What are the official names of this protein?
Non-structural protein 5, NSP5, NS26.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP5 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: SYK_PORG3
Sequence: MNILELSEQEVVRRNSLEQLRNLGIDPYPAAEYTVNAYSTEIKRNFNGDENAAKRQVSIAGRIMSRRIMGKATFMELQDAEGRIQIYITRDDICPGEDKEFYNTVVKKCTDIGDFIGVKGYVFRTQMGEISVHVQEMTFLSKAIRPLPVVKEKDGEVFDGFTDSEQRYRQRYVDLVVNSHVKDIFLKRTMVFNSMRSFFNERGYIEVDTPVLQSIPGGAAARPFITHHNALDIPLYLRIANELYLKRLIVGGFDGVYEFSRNFRNEGMDRTHNPEFTAMEIYVAYKDYNWMMNFTEQMLERICMDVLGTTQVKVGEKLIDFKAPYRRVTMIEAIHEHTGIDISGMNEAELRQVCDKLGVEHNETMGKGKLIDEIFGEKCEKNYIQPTFITDYPKEMSPLTKEHRTNPELTERFELMVNGKELANAYSELNDPIDQRERFEEQLKLSEKGDDEAMYIDNDFIRALEYGMPPTSGMGIGMDRLVMLLTGQESIQEVLLFPQMKPEKVAPRDTKEKFAVCGIPEEWVPVLHKAGYLTVQSMREDKPGKVMQQLMDINKKYKLGLAGLNLETVSAWQEAPYE
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLGC_BACSU
Sequence: MTAFHSLNVSASALTAQRVRMDVVSSNLANMDTTRAKQVNGEWVPYRRKMVSLQSKGESFSSILNSQMSGSGNAGNGVKVSKITEDDSDFNLVYDPTDPDANAEGYVQKPNVDPLKEMVDLVSSTRSYEANVTAMNATKGMLMKALEIGK
What are the official names of this protein?
Flagellar basal-body rod protein FlgC.
What is the protein family that this protein belongs to?
Belongs to the flagella basal body rod proteins family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: HIS5_BACSU
Sequence: MIGVIDYGMGNLYSVSKALERVGVPYFVSEKPEELKEADAFILPGVGSFGDAMDNLGYTKLDQLIHDMVSEGRLLLGICLGMQLLFEESEENGTASGLGLLKGKAVRLKAEDEKGNKLKVPHMGWNRLSFHNESPLLTKTEQGYAYFVHSYYIDGMEENALLASADYGVRVPAVVGKRNVFGAQFHPEKSSTVGMSILTQFTKMAAEQKVKK
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_DEHMC
Sequence: MITANSFERTIGGRKLVIESGKLARLADAAITIRYADTELLVTLCSAKKPREGVDFLPLTIDYEERMYAAGKIPGGFIRREGRPSEQAILAGRLTDRPLRPLLPKEWRNDLQIIITVIASDKENDADIWGVVGASTVLAMSEIPYEGPVGASRIGYINGEFVLNPTFAQLESSQLDLVVVSTRKAVVMIEAGSKEIPEDIMINAIEFAHKANQELIDLQDEIRAKLGKEKLPVPVLEIPEEVKTAVAAFVKGRVNEALSHQDKTARENAVEGLQAELVAALSETFAEGDILAAYDKEIKKAIRSTILEKDIRVNGRGIKQLRQLDAETGLLPRVHGSALFTRGDTQVMAITTLGSLQESQQLDGLSAEDTKRFMLHYNFAPFSTGEVKRSGSPGRREIGHGALAERALVPVLPTPEEFPYTIRLVADVVGSSGSTSMGSVCSSSLSLMDAGVPVKKAVAGISIGLITGENDTYCTITDIEGIEDNYGDMDFKVAGTRDGITAIQVDMKVKGISFDIIRDAIYQAKEARYNILDVMDKALAQPKTELSPYAPRMYKINIDPSKIGSVIGSGGKTIRSIIEQTNTTVDIENDGTVVIGATDEASAKKAIKIIEDLTKDIEAGSIYTGKVTRIMTFGAFVEILPGKEGMVHISELADHRVEKVEDIVKVGDDITVKVIEIDNQGRVNLSHRVILNPNAVPISRNRDSQPRRPGPFRPSDRSNS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.