PharMolix/UniProtQA huggingface dataset:
Protein: TIM10_CAEBR
Sequence: MATDAQMAQVAELEVEMMSDMYRRMTNACQAKCIATAFKESELTKGEAVCLDRCVAKYLDVHEKLGKRLTSMSQGDEAALQKIAQQ
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: LEXA_MARN8
Sequence: MKLTARQSQVLDIIRRYVDETGYPPTRAEIAAELGFRSANAAEEHLRALARKGAIEMVPGASRGIRLPEAEEDLGLPVIGQVAAGSPILAQEHIEDHCTLQPGFFSPSADYLLRVRGMSMKDIGILDGDLLAVHSTQDVHNGQIVVARVGEEVTVKRFRREGNKVWLIAENEEFAPIEVDLAEQELFIEGLGVGVIRRSDLH
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: CH10_LEVBA
Sequence: MLKPLGDRVILDQPQEEETTVGGIVLASNAQEKPSTANVVAVSDGRVLDNGDKVAPTVKVGDKVLFDKYAGTEVKYDGQTYLVLHEKDLVAVID
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_VARPS
Sequence: MSLRIYNTLSRELEEFSPLQPGRVRMYVCGMTVYDLCHLGHARSMIAFDLVQRWLKASGLAVTYVRNITDIDDKIIRRAVENGETIRSLTDRMIDALHEDADALGIERPTHEPRATDYIPQMLSMIGTLEKKGLAYRAENGDVNYAVRKFPGYGKLSGKSIDELHAGERVAVLDGKDDPLDPVLWKSAKPSEPEEVKWASEFGPGRPGWHIECSAMACELLGETLDIHGGGEDLQFPHHENEIAQSEGATGKPLANYWMHNGFIVTDNEKMSKSLGNFFLIRDVLKKYDAETIRFFVVRAHYRRPLNYSDVHLDDARASLKRLYTSLDLVAPQALAAIDWNDPYAARFKAAMDEDFATPEAVAVLFDLAGEVNRTQSPAQAGLLKALGGCLNILQDDPKRFLRAGTTLDEATIQAQIDARAAAKAAKNFAEADRIRNDLLAQGIVLKDSPTGTTWAAAQ
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRX1A_CHICK
Sequence: SKRRDMTVFSGLFLGGLPPELRSATLKLTLSSVKDREPFKGWITDVRVNYTQTSPVESQEVRLDDEQSRLCAREDVCLNGGVCSVLNDQAVCDCSQTGFRGKDCSEEDNYVEGLAHLMMGDQGKSKGKEEYIATFKGSEYFCYDLSQNPIQSSSDEITLSFKTLQRNGLMLHTGKSADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNAWHDVKVTRNLRQHSGIGHAMVNKLHCSVTISVDGILTTTGYTQEDYTMLGSDDFFYVGGSPSTADLPGSPVSNNFMGCLKEVVYKNNDVRLELSRLAKQGDPKMKIHGVVAFKCENVATLDPITFETPESFISLPKWNAKKTGSISFDFRTTEPNGLILFSHGKPRHQKDAKHPQMVKVDFFAIEMLDGHLYLLLDMGSGTIKIKALQKKVNDGEWYHVDFQRDGRSGTISVNTLRTPYTAPGESEILDLDDDLYLGGLPENKAGLVFPTEVWTALLNYGYVGCIRDLFIDGQSKDIRQMAEIQSTAGVKPSCSRETAKPCLSNPCKNNGVCRDGWNRYVCDCSGTGYLGRSCEREATILSYDGSMFMKIQLPVVMHTEAEDVSLRFRSQRAYGILMATTSRESADTLRLELDAGRVKLTVNLDCIRINCNSSKGPETLFAGYNLNDNEWHTVRVVRRGKSLKLMVDDQQAMTGQMAGDHTRLEFHNIETGIITERRYLSSVPSNFIGHLQSLTFNGMAYIDLCKNGDIDYCELNARFGFRNIIADPVTFKTKASYVALATLQAYTSMHLFFQFKTTSLDGLILYNSGDGNDFIVVELVKGYLHYVFDLGNGANLIKGSSNKPLNDNQWHNVMISRDTNNLHTVKIDTKITTQSTAGARNLDLKSDLYIGGVAKEMYKSLPKLVHAKEGFQGCLASVDLNGRLPDLISDALFCNGQIERGCEGPSTTCQEDSCANQGVCLQQWDGFSCDCSMTSFSGPLCNDPGTTYIFSKGGGQITYTWPPNDRPSTRADRLAIGFSTVQKEAVLVRVDSSTGLGDYLELHIHQGKIGVKFNVGTDDIAIEEINAIINDGKYHVVRFTRSGGNATLQVDNWPVIERYPAGNNDNERLAIARQRIPYRLGRVVDEWLLDKGRQLTIFNSQATIKIGGKERGHPFQGQLSGLYYNGLKVLNMAAENDANIVIEGNVRLVGEVPSSMTTESTATAMQSEMSTSVMETTTTLATSTARRGKAPTKEPIGQTTDDILVASAECPSDDEDIDPCEPSSGGLANPTRAGGGREYPGSSEVIRESSSTTGMVVGIVAAAALCILILLYAMYKYRNRDEGSYHVDESRNYISNSAQSNGAVIKEKQPNSAKSSNKNKKNKDKEYYV
What is the function of this protein?
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.  May mediate intracellular signaling.
What are the official names of this protein?
Neurexin-1, Neurexin I-alpha, Neurexin-1-alpha.
What is the protein family that this protein belongs to?
Belongs to the neurexin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: USH1G_MOUSE
Sequence: MNDQYHRAARDGYLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKMQRKHHERMERRYRRELAERSDTLSFSSLTSSTLSRRLQHMTLGSQLPYSQATLHGTAKGKAKIQKKLERRKQGGEGTFKVSEDGRKSVRSLSGLQLGSDVMFVRQGTYANPKEWGRAPLRDMFLSDEDSVSRATLAAEPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYVSSGLHGLGREDGGLDGAGTPRGRLHSSPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDEDLEPETSPLETFLASLHMEDFASLLRHEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQALERPLALEDTEL
What is the function of this protein?
Plays a role in pre-mRNA splicing by regulating the release and transfer of U4/U6. U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complexes from their assembly site in Cajal bodies to nuclear speckles, thereby contributing to the assembly of the pre-catalytic spliceosome on target pre-mRNAs (By similarity).  May also participate in recycling of snRNPs back to Cajal bodies during splicing (By similarity).  Plays a role in regulating MAGI2-mediated endocytosis (By similarity).  Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells.  Required for normal development and maintenance of cochlear hair cell bundles.  Required for normal hearing.
What are the official names of this protein?
pre-mRNA splicing regulator USH1G, Jackson shaker protein, Scaffold protein containing ankyrin repeats and SAM domain, Usher syndrome type-1G protein homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, cilium. Nucleus speckle. Nucleus, Cajal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Photoreceptor inner segment. Note=Detected at the tip of cochlear hair cell stereocilia. Recruited to the cell membrane via interaction with CDH23 or PCDH15 (PubMed:21436032). In photoreceptor cilia, detected predominantly at the cilium base (PubMed:31637240). Expressed in the pericentriolar region of the centrosome (PubMed:24608321).
Protein: SURE_CALMQ
Sequence: MRILVTNDDGLTSMGIVTLANELAKEHEVHVVAPETQLSSIGAARTYNRPIRIWRWNGGLYNGPVDVYATDGTPSDAVFMGINMFKPEIVVSGVNLGENVGLESLFISGTIGAVIQSSLIGVPGIAASIEVPPHSKFIIPQINGDYFSGIVKVIKGIINHIEAEGWVKGVDALSLNMPSPSRWSGGYVVVSRMAKRLFKETVIESSDPRGNKIYWRWGEELMPLDTDTDAYAFYREGKLTVTPLILGDSSTGLSDIVRSIEELISKVIRA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCNA_THEFM
Sequence: MPFEIVFDGAKEFADLIATASNLIDEAAFKVTDEGISMRAMDPSRVVLIDLNLPESIFSKYEVEEEETIGINMDHFKKILKRGKGKDTLILKKGDENFLEITFEGTAKRTFRLPLIDVEELELDLPELPFTAKVVLLGEVLKEAVKDASLVSDAMKFIAKENEFSMRAEGETNEVEIKLTLEDEGLLDIEVEEETKSAYGISYLADMVKGIGKADEVTIRFGNEMPLQMDYFIRDEGKLTFLLAPRVED
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA, Tfu PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: OBG_SHEHH
Sequence: MKFVDEAIIRVEAGNGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLITFQFERFHIAERGKNGRGRDCTGHGGEDLILKVPVGTRAIDNDTEESLGDLTTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTDGEVRSLKLELLLLADVGLLGMPNAGKSTFIRSVSKAKPKVADYPFTTLVPNLGVVNPRPGQSFVIADIPGLIEGAADGAGLGVQFLKHLERCRVLLHILDVEPIDGSDPVESARAIVGELEKHSPKLAGKPRWLVINKADLMLEEELQERIDHIVKELEWDGDVYTISAYNREGTAELAVKLLDFIASLPPEEEVDADAEVEFKWDNYHQSANESVNEDFDDDFDDDFDEDDYDVEIIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_ECO24
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: A1AF_CAVPO
Sequence: SAIPRGLLLLAGLCCLVFGIMAEDAQVAQGPSQQIPRSLAHFAHSMYRVLTQQSNTSNIFFSPVSIATALAMVSLGAKGDTHTQILWGLEFNLTEIAEADIHDGFQNLLHTLNRPHSEHELTTGNGLFLDQKLKLKEKFSEDVKTLYHAEAFPTNFSNPKEAEKQINAYVEKGTQGKIVDLVKDLSADTVLALVNYIFFRGKWEKPFDVKHTTQEDFLVDMNTTVNVPMMKRQGMYKAFHCSTIQSWVLLLDYEGNVTTLFLLPDKGKMQHLEETLTPELIFKFARKTERMFANVHLPKLSISGTYDLKEVLGHLGITNVFSGAADLSGITEDMPLKISKGLHKALLTIDEKGTEAAGATELEITPHSVPQDLFFNKPFLFLIIDHSTDTPLFVGKVMDPTKK
What is the function of this protein?
Inhibits elastase, chymotrypsin, cathepsin G, plasmin, and trypsin.
What are the official names of this protein?
Alpha-1-antiproteinase F, APF, Alpha-1-antitrypsin, Alpha-1-proteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTS_NEIG2
Sequence: MSKSAVSPMMQQYLGIKAQHTDKLVFYRMGDFYELFLDDAVEAAKLLDITLTTRGQMDGVPIKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEVGAGKGPVERKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKTKLTTADKLNDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAGEKLLTEYFGCQDLRGFGLDSKEHAVSIGAAGALLNYIRLTQNLMPQHLDGLSLETDSQYIGMDAATRRNLEITQTLSGKKTPTLFSILDGCATHMGSRLLALWLHHPLRNRAHIRARQEAVTALESQYEPLQCHLKSIADIERIAARIAVGNARPRDLASLRDSLFELAQIDLSATGSSLLETLKAVFPETLPVAETLKAAVMPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTGLSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAFEDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAALDVLSTFSALAKERNFVRPEFADYPVVHIENGRHPVVEQQVRHFTANHTDLDHKHRLMLLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRIGASDDLASNRSTFMVEMSETAYILHHATEQIIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSFSLFATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAVAKLAGLPVRALKAAQKHLNGLENQAAANRPQLDIFSTMPSEKGDEPNVDCFVDKAEEKHFEGILAAALENLDPDSLTPREALSELYRLKDLCKSVS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: TMM17_CHICK
Sequence: MSLPEPLRRRLGSFSRTVFTDSRRAGPQYPSERADNEILSSLPLQMSLYFNVYFFPFWWLSTVFMLQLKYPVLSDYYKFILVTVMILTSLIEVIRLYLGYMGNLQEKVPELAGFWLLTLLLQLPVILFLLFNEGLNIQPLERSVNIIFALFLVFQVIAAFVTLKRMVNKLATHFHLNEFDRLEEHPVRHLYGPSKEENVLPMASMGPC
What is the function of this protein?
Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes.  Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
What are the official names of this protein?
Transmembrane protein 17.
What is the protein family that this protein belongs to?
Belongs to the TMEM17 family.
What are the subcellular locations of this protein?
Cell projection, cilium membrane; Multi-pass membrane protein. Note=Localizes to the transition zone of primary cilia.
Protein: VP6_ROTEO
Sequence: MEVLYSISKTLKDARDKIVEGTLYSNVSDIIQQFNQMIVTMNGNEFQTGGIGTLPIRNWTFDFGLLGTTLLNLDANYVETARTTIEYFIDFIDNVCMDEMTRESQRNGIAPQSDALRKLSGIKFKRINFDNSSEYIENWNLQNRRQRTGFVFHKPNIFPYSASFTLNRSQPLHNDLMGTMWLNAGSEIQVAGFDYSCAFNAPANTQQFEHIVQLRRALTTATITILPDAERFSFPRVINSADGATTWYFNPVILRPNNVEVEFLLNGQIINTYQARFGTIIARNFDTIRLSFQLMRPPNMTPAVNALFPQAQPFQHHATVGLTLRIDSAVCESVLADSNETMLANVTAVRQEYAVPVGPVFPPGMNWTELITNYSPSREDNLQRVFTVASIRSMLIK
What is the function of this protein?
Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices.  This capsid constitutes the middle concentric layer of the viral mature particle.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes.  VP6 is required for the transcription activity of the DLP.
What are the official names of this protein?
Intermediate capsid protein VP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP6 family.
What are the subcellular locations of this protein?
Virion. Note=Component of the intermediate capsid. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: HEM3_YERPB
Sequence: MLDKIIRIATRQSPLALWQAHYVQHLLQANHPGLQIELVPMVTRGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVHSMKDVPIAFPEGLGLVAICEREDPRDAFVSSHYAHLDDLPAGSVVGTSSLRRQCQLRERRPDLIIRDLRGNVGTRLAKLDNGDYQAIILAVAGLKRLGLETRIRYAMSAEESLPAVGQGAVGIECRLDDDHTRQLLAPLNHRHTELRVCAERAMNIRLEGGCQVPIGSYAELEGDTLWLRALVGAPDGSQMIRGERRGPAAEAEQMGIELADELLSRGAREILAAVYLDNPAR
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: CAST1_HUMAN
Sequence: MELHILEHRVRVLSVARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVLNVSSHSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAQEFDIYREVGGEPVPVTRDDSSNGFPRTQHGPSPTVHPIQSPQNRFCVLTLDPETLPAIATTLIDVLFYSHSTPKEAASSSPEPSSITFFAFSLIEGYISIVMDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYISTFNFDHALVPEDGIGSVIEVLQRRQEGLAS
What is the function of this protein?
Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:26972053, PubMed:27487210, PubMed:33594058).  As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1 (PubMed:26972053, PubMed:27487210, PubMed:33594058).  Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway (PubMed:26972053, PubMed:27487210, PubMed:33594058).
What are the official names of this protein?
Cytosolic arginine sensor for mTORC1 subunit 1, Cellular arginine sensor for mTORC1 protein 1, GATS-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the GATS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: THIM_DESRM
Sequence: MQEVQRLWDIRQEVRIKKPLVCNITNTVVTNFTANVLLAVGASPLMSEGWQEADDLAKIVDVLVLNMGTLHPRQVEYFIKAGKSANQEQKPVVFDPVGIGATSYRNAVAAEILDKIKLDLIRGNHGEINFLAGITGQTKGVDSLSNQISVKHLAEFANTTRTLVVSTGEVDYLSDGAKTFTNKTGHAYLQLVTGTGCALSSLAGAFMSVTEDKCLGVLSALAFYGAAAQKAALISQGPGTFAGNFLDALYGLEFDEFKKILEAPKI
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: U17PB_MOUSE
Sequence: MVVALSFPEADPAMSPPSAPELHQDEAQVVEELAANGKHSLSWESPQGPGCGLQNTGNSCYLNAALQCLTHTPPLADYMLSQEHSQTCCSPEGCKMCAMEAHVTQSLLHTHSGDVMKPSQNLTSAFHKRKQEDAHEFLMFTLETMHESCLQVHRQSEPTSEDSSPIHDIFGGWWRSQIKCHHCQGTSYSYDPFLDIPLDISSVQSVKQALQDTEKAEELCGENSYYCGRCRQKKPASKTLKLYSAPKVLMLVLKRFSGSMGKKLDRKVSYPEFLDLKPYLSQPTGGPLPYALYAVLVHEGATCHSGHYFCCVKAGHGKWYKMDDTKVTSCDVTSVLNENAYVLFYVQQNDLKKGSINMPEGRIHEVLDAKYQLKKSGEKKHNKSPCTEDAGEPCENREKRSSKETSLGEGKVLQEQDHQKAGQKQENTKLTPQEQNHEKGGQNLRNTEGELDRLSGAIVVYQPICTAN
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 17-like protein B, USP17-B, Deubiquitinating enzyme 1A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP17 subfamily.
Protein: MLTC_YERPB
Sequence: MKKILALLVIAPLLVSCSGNKNQVENEVFVKDTNGFEILMGQFAHNIENIWGLKEVLIAGPKDYVKYTDQYQTRSHINFDAGTITIETIATTNPAAHLRQAIITTLLMGDDPGSIDLYSDVNDIQISKEPFLYGQVLDNNGEPIRWEWRAAHFADYLLQNKMQTRTSGLHVISFVTIQLVPNHLDKRAHKYLPLVRKSAARYGVEESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFKLKGKSGQPSRSYLFDPENNIDAGTAYLSILQNTYLGGIQNATSRRYAVITSYNGGAGSVLRVFHSDKNKAVGIINTMSPGDVFQTLTTKHPSGESRRYLVKVNSAQKNYRRY
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: THII_ECOK1
Sequence: MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQLEGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDDRLLLIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTEQEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSKTWLLWCERGVMSRLQALYLREQGFNNVKVYRP
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB124_ARATH
Sequence: MEKMSDLPRELVEEILSRVPVKSMREVRVTCKTWNALSKHISKAEAAREGEFLGIAKKKFCRNSFLLFSIPWLRVLIVVDFSNAMKDAMKDAMKEIRSSFQAMRLIVANYDIATLSAFGEEQLAVLFQPFEGYVMEIWVTTKIEPSAVSS
What are the official names of this protein?
Putative F-box protein At2g33655.
Protein: ATPF_LOBMA
Sequence: MKNLTDSFVYLGHWPAAGSFGFNTDILATNPINLSVVFGVLIFFGKGVLNDLLDNRKQRILNTIRNSEELREGAIQQLENARARLRKVEAEADQFRVNGYSEIEREKLNLINSTSKTLKQLENYKNETILVEQQRTINQVRERIFQQALQGAIGTLNSCLSNELHLRTINANIGMFGTMKKITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NU3C_SYNS9
Sequence: MFALPGYDAFLGFLLIAAAVPVLALVTNKLLAPKSRAGERQLTYESGMEPIGGAWIQFNIRYYMFALVFVIFDVETVFLYPWAVAFNRLGLLAFIEALIFIAILLVALAYAWRKGALEWS
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3, NDH-1 subunit 3, NDH-C.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: NS12_CVPIA
Sequence: MDIWCPEKKYLRYTNGFNVSELEDVCFKYNYQFPKVGYCRVPNYAWCRNQGSFCATFTLYGKSKHYDNYFGIITGFTAFSNSLEEAVNKLVFLAVDFITWRSQSLNVYG
What are the official names of this protein?
Non-structural protein of 12.7 kDa, ns12.7, 12.7 kDa accessory protein.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns12.7 protein family.
Protein: THIN_BACSU
Sequence: MKTINIVAGGPKNLIPDLTGYTDEHTLWIGVDKGTVTLLDAGIIPVEAFGDFDSITEQERRRIEKAAPALHVYQAEKDQTDLDLALDWALEKQPDIIQIFGITGGRADHFLGNIQLLYKGVKTNIKIRLIDKQNHIQMFPPGEYDIEKDENKRYISFIPFSEDIHELTLTGFKYPLNNCHITLGSTLCISNELIHSRGTFSFAKGILIMIRSTD
What is the function of this protein?
Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate.
What are the official names of this protein?
Thiamine pyrophosphokinase, TPK, Thiamine diphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the thiamine pyrophosphokinase family.
Protein: RL4_CUTAK
Sequence: MNETKTIDVLDVKGKKAGSAELPGDLFDVNTNIPLIHQVVVAQLAAARQGTHATKTRGQVSGGGKKPWRQKGTGRARQGSTRAPQWVGGGTVHGPQPRSYAQRTPKKMVGAALRGALSDMARDNRIFVVTSLVDGDKPSTKQAKAVLSGLAELRKVLVVLDRSDEIDWLSVRNLSEVHVLAADQLNTYDVVNARTIVFSQAGLDAFVGARSANTQALSAQPEVPETNVADQHPYGEDSFRGDNPPAGFDIKGNEDSMKFHEPSSPWYGRTIAEVWFRSAAAAEAAGFVNAVKSDSEKEDAK
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.