PharMolix/UniProtQA huggingface dataset:
Protein: MIAB_XANOP
Sequence: MPGTSVSDLSTATAVDAPALLPLPVARPSAPAVVRGKLYIKTHGCQMNEYDSAKMADVLAASEGLELTDNPEEADVVLVNTCSIREKAQEKVFSQLGRWKALKAGGKPVIIGVGGCVASQEGEAIVKRAPYVDLVFGPQTLHRLPELIRARRESGKSQVDISFPEIEKFDRLPEPRAEGPSAFVSIMEGCSKYCSFCVVPYTRGEEVSRPFEDVLVEVAQLAAQGVREINLLGQNVNAYRGAYGADAGDPAQYADLGLLIRTIAQIEGIGRIRFTTSHPLEFSDSLVDAYRDVPQLANCLHLPVQAGSDRILSAMKRGYTALEFKSRIRKLRAVRPDISISSDFIVGFPGETEADFEKTMKLIEDVGFDQSFSFVYSRRPGTPASDLQDDTPETVKQARLARLQAHISAHAASISQSMVGSVQRVLVEGPSRRDPNELTGKSENMRPVNFPGNPRLIGQFVDVLITEAMSNSLRGRIQLDDSAH
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_BURP1
Sequence: MKALLDLFKQVQQEEIFDAIKIGLASPDKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAYVVIDPGMTPLKARQIMTEEDYYNKVEEYGDEFRAEMGAEGVRELLRSINIDEQVETLRTELKNTGSEAKIKKYAKRLKVLEAFQRSGIKPDWMILEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKGGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKLMALELFKPFIFNKLEVMGVATTIKAAKKEVENQTPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQMEARTLMLASNNVLFPANGDPSIVPSQDIVLGLYYATREAINGKGEGLSFTGVSEVIRAYENKEVELASRVNVRITEMVRNEDTSEGAPQFVPKISLYATTVGRAILSEILPPGLPFSVLNKPLKKKEISRLINTAFRKCGLRATVVFADQLMQSGFRLATRAGISICVDDMLVPTQKETIVGDAAKKVKEYDRQYMSGLVTAQERYNNVVDIWSATSEAVGKAMMEQLSTEPVIDRDGNETRQESFNSIYMMADSGARGSAVQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVVEDDCGTSNGVAMKALVEGGEVVEALRDRILGRVAASDVVNPETQETLYEAGALLDETAVEDIERLGIDEVRVRTALTCETRYGLCASCYGRDLGRGSLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAVASSVEAKSNGTVRFTASMRYVTNAKGEQIVISRSGEALITDDIGRERERHKIPYGATLLQLDGAAIKAGTQLATWDPLTRPIITEYGGTVKFENVEEGVTVAKQIDDVTGLSTLVVIDVKRRGSQAAKSVRPQVKLLDANGDEVKIPGTEHAVQIGFQVGALITVKDGQQVQVGEVLARIPTESQKTRDITGGLPRVAELFEARSPKDAGILAEVTGTVSFGKDTKGKQRLVITDLEGNQHEFLIAKEKQVLVHDGQVVNKGEMIVDGPADPHDILRLQGIEALSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVQIVDNGDTRFIPGEQVERSDMLDENDRMIAEDKRPATYDNILLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAFHKARKAKEQSDRERFDQIAAEEAFEFGTPSAPAEEPQHPAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MSH5_MOUSE
Sequence: MAFRATPGRTPPGPGPRSGIPSASFPSPQPPMAGPGGIEEEDEEEPAEIHLCVLWSSGYLGIAYYDTSDSTIHFMPDAPDHESLKLLQRVLDEINPQSVVTSAKQDEAMTRFLGKLASEEHREPKGPEIILLPSVDFGPEISKQRLLSGNYSFISDSMTATEKILFLSSIIPFDCVLTVRALGGLLKFLSRRRIGVELEDYDVGVPILGFKKFVLTHLVSIDQDTYSVLQIFKSESHPSVYKVASGLKEGLSLFGILNRCRCKWGQKLLRLWFTRPTRELRELNSRLDVIQFFLMPQNLDMAQMLHRLLSHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACRSLPQSIQLFQDIAQEFSDDLHHIASLIGKVVDFEESLAENRFTVLPNIDPDIDAKKRRLIGLPSFLTEVAQKELENLDSRIPSCSVIYIPLIGFLLSIPRLPFMVEASDFEIEGLDFMFLSEDKLHYRSARTKELDTLLGDLHCEIRDQETLLMYQLQCQVLARASVLTRVLDLASRLDVLLALASAARDYGYSRPHYSPCIHGVRIRNGRHPLMELCARTFVPNSTDCGGDQGRVKVITGPNSSGKSIYLKQVGLITFMALVGSFVPAEEAEIGVIDAIFTRIHSCESISLGLSTFMIDLNQVAKAVNNATEHSLVLIDEFGKGTNSVDGLALLAAVLRHWLALGPSCPHVFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGEDLVFFYQLCQGVASASHASHTAAQAGLPDPLIARGKEVSDLIRSGKPIKATNELLRRNQMENCQALVDKFLKLDLEDPTLDLDIFISQEVLPAAPTIL
What is the function of this protein?
Involved in DNA mismatch repair and meiotic recombination processes.  Facilitates crossovers between homologs during meiosis (By similarity).
What are the official names of this protein?
MutS protein homolog 5.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL131_BRANA
Sequence: MKHNNVIPNGHFKKHWQNYVKTWFNQPARKTRRRVARQKKAVKIFPRPTAGPLRPVVHGQTLKYNMKVRTGKGFTLEELKSAGIPKKLAPTIGIAVDHRRKNRSLEGLQSNVQRLKTYKAKLVIFPRRARKVKAGDSTAEELANATQVQGDYMPIVREKHATELVKLTTEMKSVKAFDKIRLERTNKRHAGARAKRAADAEKEEKK
What are the official names of this protein?
60S ribosomal protein L13-1, Cold-induced protein C24A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL13 family.
Protein: EFV_ENTFA
Sequence: MSQLNKWQKELQALQKANYQETDNQLFNVYRQSLIDIKKRLKVYTENAESLSFSTRLEVERLFSVADEINAILQLNSPKVEKTIKGYSAKQAEQGYYGLWYTLEQSQNIALSMPLINHDYIMNLVNAPVAGKRLSKRLYKYRDELAQNVTNNIITGLFEGKSYAEIARWINEETEASYKQALRIARTEAGRTQSVTTQKGYEEAKELGINIKKKWLATIDKHTRRTHQELDGKEVDVDEEFTIRGHSAKGPRMFGVASEDVNCRCTTIEVVDGISPELRKDNESKEMSEFKSYDEWYADRIRQNESKPKPNFTELDFFGQSDLQDDSDKWVAGLKPEQVNAMKDYTSDAFAKMNKILRNEKYNPREKPYLVNIIQNLDDAISKFKLKHDIITYRGVSANEYDAILNGNVFKEFKSTSINKKVAEDFLNFTSANKDGRVVKFLIPKGTQGAYIGTNSSMKKESEFLLNRNLKYTVEIVDNILEVTILG
What is the function of this protein?
A probable mono(ADP-ribosyl)transferase, it may ADP-ribosylate Arg in target protein(s).  Upon expression in yeast cells causes cell death.
What are the official names of this protein?
NAD(+)--arginine ADP-ribosyltransferase EFV, Putative mono(ADP-ribosyl)transferase, mADPRT, mART, Toxin EFV.
What are the subcellular locations of this protein?
Secreted.
Protein: DTD_DESOH
Sequence: MRAVIQRVQKSSVTVDGHVVGSIGPGLLVLLGVAGNDEQKDAEFLANKITSLRIFEDDAGKMNRSVIDTGGGVLVVSQFTLLADCRKGRRPSFVQAAEPRKAEALYLAFVEAVKNRGLTTATGTFGAMMDVSLVNDGPVTFVIESQ
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNA_PSE14
Sequence: MSPKAVVFAYHDIGCVGLQALLGAGYEIAAVFTHADDPKEKTFFGSVAQLCARHGIPVHAPEDPNHPLWVERIDKLAPDFIFSFYYRQLLGDPLLACAKKGALNLHGSLLPRYRGRAPANWVLVNGESETGVTLHQMVKRADAGPIVAQQRVSISSTDTALTLHGKLREAAADLLSETLPLLALGQLSGTPQDETRASCFGRRTPADGLIDWSLPATQLYNLIRAVTQPYPGAFCAVGENKLIVWAASAEAGNNGEAPGTVISHDPLRIACGEGSLVINAGQRGDNGLYLSGAQLAREFGLVEGSQLLDTEKRRPARRTRVLILGVNGFIGNHLSERLLQDDRYDIYGMDIGSDAIERLRTKPNFHFIEGDISIHTEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKIVRYCVKYNKRVIFPSTSEVYGMCQDASFNEDTSNLIVGPINKQRWIYSVSKQLLDRVIWAYGQKGLQFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCFTDVADGIEALARIIENRDGCCNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRGNFPPFAGFREVESQSFYGKGYQDVSHRKPSIDNARQLIGWTPGIELSETIGKTLDFFLREAMAEKADMR
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: EPMA_SALDC
Sequence: MSETATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGINLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQQPIDQNLLDALAAGLPDCSGVALGIDRLVMLALGAESLADVIAFTVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: FEN1_CANAL
Sequence: MGVKGLNQLIKEHSPSAYKEFQLKNLFGRKVAIDASMCLYQFLIAVRQSDGQQLTNEDGETTSHLSGMFYRTIKMVENNIKPVYVFDGKPPVLKGGELEKRLLRREEAQKQKTALGDEGTVEEVLKFEKRLVRVTREQNEEAKKLLQLMGIPCVDAPCEAEAQCAELARGGKVYAAASEDMDTLCYEPPFLLRHLTFSEARKMPIDQIEYKDAIAGLDMTKEQFIDLCILLGCDYCESIKGIGQATAFKLIKEHGSLDNIVEWIKNNKTKYTLPENWPYDEARQLFMNPEVTNASEINLKWKEPDVDGLIEFMVKQKGFSEDRIRSGAEKLKKGLKGGVQGRLDGFFKVVKTDDKKRKADPKESKASKKKKK
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: RS21_STRTD
Sequence: MSKVVVRKNESLDDALRRFKRSVTKAGTLQEARKREHYEKPSVKRKRKSEAARKRKKI
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ENGB_LACDA
Sequence: MIINQSEFSVSAVKASQYPEGGLDEIALAGRSNVGKSSFINTLLQRKNLARTSSSPGKTQTLNFYRVDSDQADFYLVDVPGYGYAKVSKKQREEFGEMIQDYLETRAYLKGLILMIDGRHEPTVDDIAMYDYAQYLNLPILLVATKMDKIKKNAFNKTEAAFRKHLNLNKDNVTFLPFSSVTKLNVDQVKDWIQARLYEE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: RECA_LEIXX
Sequence: MPSPADREKALVTALAQIDRQFGKGSVMRLGSDERAPVEVVPTGSIALDVALGIGGLPRGRIVEIYGPESSGKTTLTLHAIANAQRAGGIAAFIDAEHALDPDYARKLGVDIDALLVSQPDTGEQALEIADMLVRSGSIDLIVIDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLTGALSQTNTTMIFINQLREKVGVFFGSPETTAGGKALKFYASVRLDIRRIETLKDGTDAVGNRTRVKVVKNKMAPPFKQAEFDILYGVGISHEGSLLDFGVEHALVKKSGAWYTYEGDQLGQGKENSRNFLIANPDIAAEIENKIKIKLGIVADPNADAEPTAAAGSLEEKLPARKGA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_NOCFA
Sequence: MPMPTEERVSQLVAGLVERRGFDLEGVEITRAGSRADAQPRVTVVVDSDGAADLDAVAELSSEMSVVLDDTDIFGDSPYLLEVTTPGVDRPLTAPRHWRRAQGRKVRITLRPGAEPPDPGGSAGFEARVGVLDGEQIALVLGGKRNPHRVRVPLADIERAVVQVEFSPPGARELELAGGVAPGRPDPGTDRAIAADGAISEETSTAAASDPTEGIEE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_XANAC
Sequence: MKFFASCAKGLEYLLADELLALGASRATATISGVNVEGELRDAQRAVLWSRLASRVLWPLTEFDCPDEDALYAGVAELPWDAHLSVGHTLSVDAHVSGTAITHARYAAQRIKDAVVDTMRRQGLERPSVDVENPDLRLNLSLRKGRATISVDLGGGPLHRRGWRMAQNEAPLKENLAAAVLMRGGWPRAYADGGGLLDPMCGSGTLLIEGALMAADVAPGLQRYGSDVPSRWRGFDRDGWQQLVGEARERDRVGRAALKQVIHGSDMDPHAIRAAKENAQVAGVAEAIWFGVREVGELQTPPQATGVVVCNPPYDERLAADAALYRRLGDTLQRVAPQWRASLLCGNAELAYATGLRAGKKYQLFNGAIECALIVCDPIAVPRRTPLAAPTALSEGAQMVANRLRKNLQKFKKWRAREGIECFRAYDADLPEYSAAIDVYQQADGDRRIFLHVQEYAAPATIPEADVRRRLNELLAAAREVFEVPAERVALKSRERGKGGSKYGRFEQRNEIVHVREHGALLRVNLFDYLDTGLFLDHRPLRGTMAQQCRGRRFLNLFCYTGVASVEAAVAGAASTTSVDLSATYLQWCADNLALNGLAGSKHKLVQADALAWLEAERAHFDVIFCDPPTFSNSARAEDFDIQREHVRLLRAAVARLAPGGVLYFSNNFRRFKLDEEGVAEFAQCEEISPRTIDPDFERHARIHRAWRLTA
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_ECO8A
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14Z_TREPS
Sequence: MATVAMINKAKATPKYATRRYNRCGVCGRPRGYMRRFQLCRLCFRKLASEGQIPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: FOXP2_RAT
Sequence: MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSGDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQCQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSQEDNGIKHGGLDLTTNNSSSTTSSTTSKASPPITHHSIVNGQSSVLNARRDSSSHEETGASHTLYGHGVCKWPGCESICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSSVTMSKNMLETSPQSLPQTPTTPTAPVTPITQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRSQKITGSPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNPGLINNASSGLLQAVHEDLNGSLDHIDSNGNSSPGCSPQPHIHSIHVKEEPVIAEDEDCPMSLVTTANHSPELEDDREIEEEPLSEDLE
What is the function of this protein?
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium.  May also play a role in developing neural, gastrointestinal and cardiovascular tissues.  Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential (By similarity).  Plays a role in synapse formation by regulating SRPX2 levels.
What are the official names of this protein?
Forkhead box protein P2.
What are the subcellular locations of this protein?
Nucleus.
Protein: OTU6A_HUMAN
Sequence: MDDPKSEQQRILRRHQRERQELQAQIRSLKNSVPKTDKTKRKQLLQDVARMEAEMAQKHRQELEKFQDDSSIESVVEDLAKMNLENRPPRSSKAHRKRERMESEERERQESIFQAEMSEHLAGFKREEEEKLAAILGARGLEMKAIPADGHCMYRAIQDQLVFSVSVEMLRCRTASYMKKHVDEFLPFFSNPETSDSFGYDDFMIYCDNIVRTTAWGGQLELRALSHVLKTPIEVIQADSPTLIIGEEYVKKPIILVYLRYAYSLGEHYNSVTPLEAGAAGGVLPRLL
What is the function of this protein?
Deubiquitinating enzyme that hydrolyzes 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.  Also able to hydrolyze 'Lys-11'-linked ubiquitin chains.
What are the official names of this protein?
OTU domain-containing protein 6A, DUBA-2.
Protein: RTCB1_CULQU
Sequence: MVVRDYNTELTYIERISTNSFRIKKGFQPNMNVEGIFYANSRLEKLMFDELRNSCRPGMTGGFLPGVKQIANVAALPGIVGRSVGLPDIHSGYGFAIGNMAAFDMSDPTSIVSPGGVGFDINCGVRLLRTNLFEKDVKPVQEQLAQSLFDHIPVGVGSKGIIPMNAHDLEEALEMGMDWSLREGYVWAEDKEHCEEYGRMLTADPSKVSMRAKKRGLPQLGTLGAGNHYAEIQVVEEIYDKYAASKMGIEELGQICVMIHSGSRGFGHQVATDALVEMEKAMKRDKIETNDRQLACARINSVEGQNYLKAMSAAANFAWVNRSSMTFLTRQAFAKQFNTTPDDLDMHVIYDVSHNVAKIEEHIVDGRPKQLLVHRKGSTRAFPPHHPLIPVDYQLTGQPVLVGGSMGTCSFVLTGTEKGMAETFGSTCHGAGRSLSRAKSRRNLDYKDVLRDLEAKGISIRVASPKLVQEEAPDSYKDVRDVVQTCHDVGISSKCIKLRPIAVIKG
What is the function of this protein?
Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.  May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
What are the official names of this protein?
RNA-splicing ligase RtcB homolog 1, 3'-phosphate/5'-hydroxy nucleic acid ligase 1.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: MDH_SALPA
Sequence: MKVAVLGAAGGIGQALALLLKNQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAKTCPKACVGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKLPTEVEVPVIGGHSGVTILPLLSQIPGVSFTEQEAAELTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRALQGEKGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQHSLDAMLDTLKKDIQLGEDFINK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: LPXH_CELJU
Sequence: MNTLFISDLHLHSSRPQITRAFFDFLRQQTHHTQALYILGDFFDAWIGDDDDDPLPNAVAEQLKKLNSAGVAIFLMHGNRDFLLGNSYAQRAGATLIAEGTVIDLYGRPALLLHGDDLCTLDTDYMAFRQQVRNPDWQAQLLAQPLAARRALAAQLRAQSQAINNMKAESIMDVTPDEVVRVMEEAGVDLLIHGHTHRPARHPLTVQGRPAERIVLGDWHHQGWCLDASATGLALRNWDI
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL28_BORBR
Sequence: MARVCQVTGKGPMVGNNVSHANNKTKRRFLPNLQSRRFWVESENRWVRLRVTAKAIRTIDKNGIDAVLADLRARGEAV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: HIS2_ECOLI
Sequence: MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTLESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLLQDQGLDLTTVIENLRKRHQ
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisIE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBK_COFAR
Sequence: MLNIFSLIWICLNSALYSSGFFFGKLPEAYAFLNPIIDFMPVIPVFFFLLAFVWQAAVSFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: POF1B_HUMAN
Sequence: MSSSYWSETSSSSCGTQQLPEVLQCQPQHYHCYHQSSQAQQPPEKNVVYERVRTYSGPMNKVVQALDPFNSREVLSPLKTTSSYQNLVWSDHSQELHSPTLKISTCAPSTLHITQNTEQELHSPTVKLTTYPQTTIRKYVVQNPEQEPLSQFLRGSHFFPGNNVIYEKTIRKVEKLNTDQGCHPQAQCHHHIIQQPQVIHSAHWQQPDSSQQIQAITGNNPISTHIGNELCHSGSSQICEQVIIQDDGPEKLDPRYFGELLADLSRKNTDLYHCLLEHLQRIGGSKQDFESTDESEDIESLIPKGLSEFTKQQIRYILQMRGMSDKSLRLVLSTFSNIREELGHLQNDMTSLENDKMRLEKDLSFKDTQLKEYEELLASVRANNHQQQQGLQDSSSKCQALEENNLSLRHTLSDMEYRLKELEYCKRNLEQENQNLRMQVSETCTGPMLQAKMDEIGNHYTEMVKNLRMEKDREICRLRSQLNQYHKDVSKREGSCSDFQFKLHELTSLLEEKDSLIKRQSEELSKLRQEIYSSHNQPSTGGRTTITTKKYRTQYPILGLLYDDYEYIPPGSETQTIVIEKTEDKYTCP
What is the function of this protein?
Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton.  May be involved in ovary development.
What are the official names of this protein?
Protein POF1B, Premature ovarian failure protein 1B.
What are the subcellular locations of this protein?
Cell junction, tight junction.
Protein: SYS_CLOBB
Sequence: MLDLKRIRNNPEEIKKLLSNRGEDFDVAVIDEIVTLDEERRKILVEVESLKSKRNQVSAEIPKLKKAGEDVTEIMNDMRKLGEEIKNFDTRVNEINERIEYIMLRIPNIPNPEVPDGETDEDNVEIKKWGEPTKFNFEPKAHWDLGTDLNILDFERGGKVAGSRFTVYKGLGARLERSIINYFLDKHTTENGYTEILPPYMVNRDSMTGTGQLPKFEEDAFKVENNGYFLIPTAEVPVTNMYRNEVLSGDILPIKHAAYSACFRAEAGSAGRDTRGLVRQHQFNKVELVKFCKPEDSYAELDKLVEDAESVLQGLGLPYRIVRICKGDLGFTAALKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIKYRETPKDKPKFIHTLNGSGVAIGRTVAAVLENYQKEDGTVEIPEAIKRFMNVDFIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.