PharMolix/UniProtQA huggingface dataset:
Protein: PLK4_DROAN
Sequence: MLSNRAFGETIEEYEVQHLLGKGGFASVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIGRPFTEAEAASILRQVVAGLLYLHSHNIMHRDISLSNLLLSKEMHVKIADFGLATQLKRPDERHVTMCGTPNYISPEVVSRTSHGLPADVWSVGCMLYTLLVGRPPFETDAVQTTLNKVVLSEYIMPTHLSFEAQDLINKLLKKVPHERIALEHVLRHPFLTKRLENSSNGVYSTPGALNVFSQSLESGDSGIITFASSDSRNSQRLRSVENTAPLQGLPQIQEEYMQDKYRPTYDQPGLFKQPSSTRMEHNWLTTEKDTPFRMDVPMKEKPAPLKEERISVPPLNTKRLLPTRYKTKNAIMSILRNGEVVLEFLKYRPKFNEDRVTDICRISDDGRRIIIYQPDPGRGLPIRDHPPELQIPNEDCVYNYDSLPSKHWKKYVYADRFVGLVKSKTPKVTYFSALGKCQLMETMTDFEIRFYSGAKLTKSPSEGLKVHNANGMLLSDHVGSEARSMIDHGNECFTHCVSISNALEMAQTKDNSCFPVTIGRRPVTEVQPSQRLDGLRDTTNFAYSTPKSNQGSINFSVSTISSIRNTTDFGSNSSRTNMRASQQNIPIKRINLPDIGVATELSHGVVQVQFYDGSVVSIIPDIQGGGVTYTQSNGISTHFGKDDDLPFTVREKLSQLPHIQLKLKTAPLLSNSRKIEFNAMTPKTTTPCYNRMLL
What is the function of this protein?
Serine/threonine-protein kinase that plays a central role in centriole duplication.  Able to trigger procentriole formation on the surface of the mother centriole cylinder, using mother centriole as a platform, leading to the recruitment of centriole biogenesis proteins such as sas-6.  When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase.  Centrosome amplification following overexpression can initiate tumorigenesis, highlighting the importance of centrosome regulation in cancers (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase SAK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: METR_SHIFL
Sequence: MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRLGFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQWLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFDYEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSVDNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQPVTEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL
What is the function of this protein?
Control of the last step in methionine biosynthesis; MetR is a positive activator of the metA, metE and metH genes.  It is also a negative regulator of its own expression (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator MetR.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_THIDA
Sequence: MKALLDLFKQATHEEEFDAIKIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEGFVVVEPGMTPLNRGQLLTEEDYLGKLEEYGDEFKALMGAEGVRELLRSLDVASEVETLHSEISKTGSDTKLKKLSKRLKILEGFQKSGIKPEWMILEVLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKKMALELFKPFIFNRLEVLGLATTIKAAKKMVEDEEPIVWDLLEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQAEARTLMLASNNVLSPANGEPIIVPSQDIVLGLYYMTREKVNAKGEGMMFADVTEARRAYDNREAELHARVTVRIKEVTLDENKNRVETVKRVETTLGRALLSEILPPGLPFSFVDKALKKKEISKLINASFRRCGLRETVIFADKLMYTGFTFATRAGMSIAIKDMLIPQEKGQILGAAEAEVKEIESQYTSGLVTQGERYNKVVDIWGRAGDAVAKAMMGQLGGEKVTDRQGKEVTQESFNAIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNMLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEDDCGTKNGLLVKALVEGGEVVEALRERILGRVAASDIINPETQETVFEAGTLLSEDVVDTIEALGIDEVRVRTPLTCETRYGLCANCYGRDLGRGYLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQLEAKSNGAVQYTATMRYVTNARKELVAISRSGEILIADDSGRERERHKVPYGATLMVTDGAKIKAGAVLATWDPHTRPIITEYAGRVRFENVEEGVTVAKQVDDVTGLSTLVVIDPKRKSTSTKGVRPQVKLLDDAGNELKIAGTDTLVNITFQIGSIITVKDGQDVAVGDVLARIPQETSKTRDITGGLPRVAELFEARSPKDAGVLAEVTGTVSFGKDTKGKQRLVITDLDGVAHEYLITKEKHVTAHDGQIVQKGEMIVDGPVDPHDILRLQGVEALASYITDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVADPGDTGLIPGEQVERSEVLQINDEMIAAGKEPAVYDPILLGITKASLSTDSFISAASFQETTRVLTEAAIMGKKDELRGLKENVIVGRLIPAGSGLAYHNTRRRQAAGEDMGADRLLEGGETPAAENQEVA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: NEP_I78A8
Sequence: MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHLLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: CH60_COLP3
Sequence: MAAKDVLFGNDARTKMLRGVNVLADAVKVTLGPKGRNVVIDKSFGGPTITKDGVTVAKEIELDDKFENMGAQMVKEVASKANDEAGDGTTTATVLAQAIVNEGLKSIAAGMNPMDLKRGIDKAVIAAVAALKDASTPVTDNKAIEQVGTISANSDETVGQIIATAMDKVGAEGVITVEEGQALTDELDVVEGMQFDRGYLSPYFINKQENGTVELENPFILLVDKKVSNIRELLTTLEAVAKSGKPLLIIAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDVATLTAGTVISEEIGMELEKATLEDLGQAKRVVISKDTTIIIDGIGEEADIKARVSQIRGQIEDSSSDYDKEKLQERLAKLAGGVAVIKIGAATEIEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRAAEAIKDLEGINEDQTHGINVAIRAMEAPLRQIVANCGDEASVVLNEVRNGEGNYGYNAGNSTYGDMIAMGILDPTKVTRSALQFAASVAGLMLTTEAMITDAPQDSAPAMPDMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_CHLTB
Sequence: MLSNTLRSNFLKFYANRNHTPVASSPVFPHNDPSILFTNAGMNQFKNIFLGKEQTSYTRATTSQKCIRAGGKHNDLENVGHTSRHLTFFEMLGNFSFGDYFKQDAISFAWEVSLSVFNFDPDFIYATVHEKDDEAFALWEKYLPTDRIFRLTDKDNFWSMADTGPCGFCSELLFDRGEKFGKAASPLEDVDGERFLEYWNLVFMEFNRTSDGTLLALQKKCVDTGAGLERLVSLLAETKTVFEADVLRHLISKIENLSGTTYSPTEAKGAAFRVIADHIRSLSFAIADGLLPGNTERGYVLRKILRRAVNYGKRLGFNRPFLADVVPSLVDVMGEAYPELSASVTQIQEVLTTEEEHFFKTLQRGGNLLQQVLKSSASSAKISGEDAFKLKDTYGLPIDEIALLAKDYNYAIDMDTFEKLEVEAKERSRKNTKKTKNDSDSVFQDLDPTNTSEFIGYDTLSCDTFIEGIIKYNEIASSLEEGDEGAIILRTTPFYAEKGGQIGDSGEIFCESGTFLVSHTIAPKAGLIVHLGKLSQGSLTTTMAVTAQVNQNLRKKTANNHTGCHLLHKALEMTLGEHIRQAGSYVDSQKIRLDFTHNKALSPEDLLAIETLVNEKIRENDPVTIREVLYSDVMSSSEIKQFCGDKYGDIVRVVLAGFSHELCGGTHAQATGDIGYFRITKEHAVATGIRRIEATTGEDAENIARGQDVDLNEIATVIQSPKDQILVKIRSVMEEKKDLAKQVADLENQLVQQQVKTLLTSCEKICDTSYLVYYLTEEEGQRIQHYANAIHKEIPTNFISLWITEKNGRYIVLSRVSDDLTKRGVQAHTLLAELLAPYGGRCGGKAISAQGSSAELPQIEFLNKTLRQWISTQLA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR9_AZOVD
Sequence: MTDQTTRLPVRRALISVSDKTGVVDFARELAALGVEILSTGGTFKLLREHGVDAVEVADYTGFPEMMDGRVKTLHPKIHGGILGRRDLDAAVMAEHGIQPIDLVAVNLYPFAATVARPGCTLAEAIENIDIGGPTMVRSAAKNHKDVAIVVNAADYAGVLESLKNGGLTYAQRFDLALRAFEHTAAYDGMIANYLGTIDQGAETLTTEGRAAFPRTFNSQFVKAQDMRYGENPHQQAAFYVETSPAEASVATARQLQGKELSYNNVADTDAALECVKSFVKPACVIVKHANPCGVAVVPEDEGGIRKAYDLAYATDSESAFGGIIAFNRELDGATARAIVERQFVEVIIAPSVSAEAREAVAAKANVRLLECGQWPAERADGLDFKRVNGGLLVQSRDIGMIAEADLKVVTRRAPTEREIHDLIFAWKVAKFVKSNAIVYARNRQTIGVGAGQMSRVNSARIAAIKAEHAGLEVAGAVMASDAFFPFRDGIDNAAKAGITAVIQPGGSMRDNEVIAAADEAGMAMVFTGMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: SYC_BORHD
Sequence: MLLKLYNTKTKSLSDIKNFSDTKVYACGPTVYNYAHIGNLRTYIFEDLLIKSLRLLKYNVNYAMNITDIGHLTGDFDEGEDKVVKAARERGLTVYEISRFFTEAFFDDCAKLNIVYPDKVLVASEYIASMIEVVKVLEQNGFTYFVNGNVYFDTSRFNGYGQMAGINLNNFGRSSVSRVEIDLSKKNKSDFVLWFTNSKFKDQEMKWDSPWGFGYPSWHLECAAMNLDYFKSTLDIHLGGVDHVGVHHINEIAIAECYLNKMWCDMFVHGEFLIMEDEKMSKSNNNFITIKDLESDGFSPLDFRYFCLTAHYRTQLKFTFSNLRACKIARENMLNKLTFFYSSLSQFDMALLNKNCENIESVSENKYYNNFLEKIAFDLSIPQALALLWDIVKDDDLSALLKLLLAFKFDEVLSLGLKEGVLREIERDRVNIDDTMHSLIEERRLAKLRKDFKRADEIREYFRSKGFVLIDTEEGTKVKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPG1_RICTY
Sequence: MLKNSHVCIIIWLFGFISGFNIMITGNTLNYWFAKKDIALQTIGILSFITLPYSINFLLAPVFDTVQIKCLNKILGHRLSWICLTSTTLISLTSILSFLDPGTDLVLLSFIAFIISFFSATQDTILSALRTEIVPKELLGFTSGIYIFGYRVGMLLASSGAIYLSIYLTFNKIYQIFACVIFVYLILLILVSRYTNSVDVIEENTSYFYVARCYTMEEMHLKNEFFIKHYFNFFKNCISAYLLKIFSGSHVYRNDISLAYFIVLILIFLVLYRLPDNLINVMINPFLLHLGYNAFEIASVCKFCGVIGAIIGGLIGGIIMKYKNMLYSILLFGIIHALSHILFILLEVNGKNSLILFITIGIESITGGMTMTAYIAFISSLCQGKFRATQYSLLSSMMGISRSIFPIISGYMVVNFGWQNFFLFTTIITIPSLLILLKIQTKL
What are the official names of this protein?
Putative transporter AmpG 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROP_SALTY
Sequence: MMDSQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGGFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWASAAAFFVIINAINLTNVKVFGEMEFWFAIIKVIAVIAMILFGAWLLFSDTAGPQATVRNLWEQGGFLPHGWTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLLPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALLNVDKRGVPVSSILVSAVVTALCVLLNYLAPESAFGLLMALVVSALVINWAMISLAHMMFRRAKQQQGVKTRFPALFYPFGNVLCLLFMAAVLIIMLMTPGMAISVWLIPVWLLILGVGYLCKEKTAKTVKAH
What is the function of this protein?
Permease that is involved in the active transport across the cytoplasmic membrane of all three aromatic amino acids, phenylalanine, tyrosine and tryptophan.
What are the official names of this protein?
Aromatic amino acid transport protein AroP, Aromatic amino acid:H(+) symporter AroP, General aromatic amino acid permease.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH60_LEPIN
Sequence: MAKDIEYNETARRKLLEGVNKLANAVKVTLGPKGRNVVIDKKFGAPTITKDGVTVAKEIELEDPLENMGAQMVKEVSTKTNDVAGDGTTTATILAQSIINEGLKNVTAGANPMSLKRGIDKAVTAAVESIQKRAVKIENKKDIANVASISANNDNTIGNLIADAMDKVGKDGVITVEEAKSIETTLDVVEGMQFDRGYISPYMVTDAESMVATLNDPFILIYDKKISSMKDLIHILEKVAQAGKPLVIISEEVEGEALATIVVNTLRKTISCVAVKAPGFGDRRKSMLEDIAILTGGQVISEDLGMKLENTTLQMLGRANKVTVDKENTTIIEGKGQTKEIQGRIGQIKKQIEDTTSEYDREKLQERLAKLAGGVAVIHVGAATEVEMKEKKARVEDALSATRAAVEEGIVPGGGLTLLKAQEAVGSLKLDGDEATGAKIIFRALEEPIRMITSNAGLEGSVIVEHAKAKKGNEGFNALTMVWEDMIQAGVVDPAKVVRSALQNAASIGSMILTTEVTITDKPDKDAPNPMAGMGGGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI_YERPP
Sequence: MTLKELVVGFGTQVRSLWMIGLHAFHKRETLMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAEQKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEFKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKQKGEAENEAKPIDVKGLMP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GPMA_ACIET
Sequence: MHKLVLIRHGESTWNLENRFTGWTDVDLTPTGIEQAKNAGRLLKAEGYEFDLAYTSVLKRATRTLWHCLDEMDRTWLPVEHSWRLNERHYGALQGLNKADMAKQYGDAQVLVWRRSYDTPPPALETTDPRSERGDLRYAGLQAGEVPLTECLKDTVARVLPYWNESIAPAIRSGKRVLIAAHGNSIRALVKYLDNISDQDIVGLNIPNGIPLVYELDADLKPLRHYYLGDAEAAAKAAAAVASQGKA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: PLAG1_HUMAN
Sequence: MATVIPGDLSEVRDTQKVPSGKRKRGETKPRKNFPCQLCDKAFNSVEKLKVHSYSHTGERPYKCIQQDCTKAFVSKYKLQRHMATHSPEKTHKCNYCEKMFHRKDHLKNHLHTHDPNKETFKCEECGKNYNTKLGFKRHLALHAATSGDLTCKVCLQTFESTGVLLEHLKSHAGKSSGGVKEKKHQCEHCDRRFYTRKDVRRHMVVHTGRKDFLCQYCAQRFGRKDHLTRHMKKSHNQELLKVKTEPVDFLDPFTCNVSVPIKDELLPVMSLPSSELLSKPFTNTLQLNLYNTPFQSMQSSGSAHQMITTLPLGMTCPIDMDTVHPSHHLSFKYPFSSTSYAISIPEKEQPLKGEIESYLMELQGGVPSSSQDSQASSSSKLGLDPQIGSLDDGAGDLSLSKSSISISDPLNTPALDFSQLFNFIPLNGPPYNPLSVGSLGMSYSQEEAHSSVSQLPPQTQDLQDPANTIGLGSLHSLSAAFTSSLSTSTTLPRFHQAFQ
What is the function of this protein?
Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed.  Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction.  Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas.  Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood.  Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.
What are the official names of this protein?
Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein: 3MGH_CORGL
Sequence: MPIDFLQPADIVAPQLLGCTLTHGGVGIRITEVEAYLDSTDEAAHTYRGKTPRNAAMFGPGGHMYVYISYGIHRAGNIVCGPEGTGQGVLLRAGEVVSGESIAQSRRGEGIPHARLAQGPGNFGQALGLEISDNHASVFGPSFLISDRVETPEIVRGPRIGISKNTEALLRFWIPNDPTVSGRRGYPKE
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: SAHH_CERSP
Sequence: MADFIVKDLSLADFGRKELDIAETEMPGLMALREEFGASKPLKGARIAGSLHMTVQTAVLIETLVALGADVRWASCNIFSTQDHAAAAIAASGVPVFAIKGETLEDYWAYTDKIFQFADGTCNMILDDGGDATLYILLGARVEAGETDLIAVPQSDEEVCLFNQIRKRMAETPGWFTKQRDAIKGVSEETTTGVHRLYDLHKKGLLPFPAINVNDSVTKSKFDNKYGCKESLVDGIRRATDVMMAGKVAVVCGYGDVGKGSAASLRGAGARVKVTEVDPICALQAAMDGFEVVVLEDVVQDADIFITTTGNRDVIRIEHMREMKDMAIVGNIGHFDNEIQVAALKNHKWTNIKDQVDMIEMPSGSRIILLSEGRLLNLGNATGHPSFVMSASFTNQVLAQIELWTKGADYQPGVYILPKALDEKVARLHLKKIGVKLTDVRPEQADYIGVKVEGPFKAEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_NEIMF
Sequence: MDFLIVLKALMMGLVEGFTEFLPISSTGHLIVFGNLIDFHSNHKVFEITIQLGAVLAVVFEYRQRFSNVLHGVGKDRKANRFVLNLAIAFIPAAVMGLLFGKQIKEYLFNPLSVAVMLVLGGFFILWVEKRQSRAEPKIVDVDALRPIDALMIGVAQVFALVPGTSRSGSTIMGGMLWGIERKTATEFSFFLAVPMMVAATAYDVLKHYRFFTLHDVGLILIGFVAAFVSGLVAVKALLRFVSKKNYIPFAYYRIVFGIAIIILWLSGWISWE
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NRDR_SYNR3
Sequence: MQCPSCQHTDSRVLESRAADSGKSVRRRRECLNCEFRFTTYERVETMTITVVKRSGTRETFSRSKLLTGLVRACEKTGLETNRLELLVEEIELQLQQRNQKEITSQQLGDLVLEELGDLSEVAYVRFASVYGKFSGISDFITTLDALRQRNQVKRQLAKIS
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: NT5D1_BOVIN
Sequence: MAQHFSLAACDVVGFDLDHTLCCYNLPESARLIYNSFAQFLVKEKGYDKGLLTVTPEDWDFCCKGLALDLEDGNFIKLADNGTVLRASHGTKMLSAEALAEEFGRKEWKHFMPDTGMAFRSGKYYFYDNYFDLPGALLCARVVDSLTKQNNGQKPFDFWKDIVAGIQHNYKMSAFKENCGIYFPEIKRDPGKYLHTCPESVKKWLRQLKNAGKILMLITSSHSDYCRLLCQYILGNDFEDLFDIVITNALKPGFFSHLPSQRPFRTLENDEEREALPFLDKPGWYSQGNAVHLYELLKKMTGKPEPKVVYFGDSMHSDIFPACHYSNWETVLILEELRGDKDGKPEESEPEEKKGKYEGSKAKPLNTSSKKWGSFFIDSVSGLENREDSLVYTWSCKRISAYSTIAIPSIEAIAELPLDYKFTRFSSNNSKTAGYYPNPPLVLSNAGKLTAK
What are the official names of this protein?
5'-nucleotidase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein: ILVC_PARXL
Sequence: MKVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKESGVNITVGLRKGGASWSKAENAGLQVKEVAEAVKGADVVMMLLPDEQIAEVYAKEVHANIKQGAALAFAHGFNVHYGQVIPRADLDVIMIAPKAPGHTVRGTYSQGGGVPHLIAVAQDKSGAARDIALSYAAANGGGRAGIIETNFREETETDLFGEQAVLCGGTVDLIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRIVTAETKKAMKAVLTDIQTGEYAKSFILENKAGAPTLQSRRRLTAEHQIEQVGSKLRAMMPWIAKNKLVDQSKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ILV5_PEA
Sequence: MAAVTSSCSTAISASSKTLAKPVAASFAPTNLSFSKLSPQSIRARRSITVGSALGATKVSAPPATHPVSLDFETSVFKKERVNLAGHEEYIVRGGRDLFHLLPDAFKGIKQIGVIGWGSQGPAQAQNLRDSLVEAKSDIVVKVGLRKGSSSFNEAREAGFSEEKGTLGDIWETISGSDLVLLLISDSAQADNYEKIFSHLKPNSILGLSHGFLLGHLQSIGLDFPKNFSVIAVCPKGMGPSVRRLYVQGKEINGAGINSSFGVHQDVDGRATNVALGWSVALGSPFTFATTLEQEYKSDIFGERGILLGAVHGIVESLFRRYTENGMSEDLAYKNTVESITGVISKTISTQGMLAVYNALSEDGKKEFEKAYSASFYPCMEILYECYEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGKIDQTRMWKVGERVRSTRPAGDLGPLYPFTAGVFVAMMMAQIEVLRKKGHSYSEIINESVIESVDSLNPFMHARGVSFMVDNCSTTARLGSRKWAPRFDYILTQQALVAVDSGAPINQDLISNFVSDPVHGAIQVCAELRPTLDISVPAAADFVRPELRQCSN
What are the official names of this protein?
Ketol-acid reductoisomerase, chloroplastic, Acetohydroxy-acid reductoisomerase, Alpha-keto-beta-hydroxylacyl reductoisomerase.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y965_MYCBO
Sequence: MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIPDSIAYPFESDSKYPYTPDGNREFMDGKPFIETFVLTAALGAVTTRLRFNFFVLKLPIRPPALVAKQAGSLAALIGNRVGLGVGTSPWPEDYELMGVPFAKRGKRIDECIEIVRGLTTGDYFEFHGEFYDIPKTKMTPAPTQPIPILVGGHADAALRRAARADGWMHGGGDPDELDRLIARVKRLREEAGKTSPFEIHVISLDGFTVDGVKRLEDKGVTDVIVGFRVPYTMGPDTEPLQTKIRNLEMFAENVIAKV
What are the official names of this protein?
Uncharacterized protein Mb0965c.
Protein: NAMB2_TRITD
Sequence: MGSSDSSSGSAPPRHQPPPPQQGSAPELPPGFRFHPTDEELVVHYLKKKAAKVPLPVTIITEVDLYKFDPWELPEKATFGEQEWYFFSPRDRKYPNGARPNRAATSGYWKATGTDKPILASGCGREKVGVKKALVFYRGKPPKGLKTNWIMHEYRLTDASSSATTSRPPPVTGGSRSASLRLDDWVLCRIYKKINKAAAGDQQRSMECEDSVEDAVTAYPLYATAGMTGAGAHGSNYDSLLHHQDSHEDNFLDGLLTAEDAGLSAGPTSLSHLAAAARASPAPTKQFLAPSSSTPFNWLDASTVGILPQARNFPGFNRSRNVGNMSLSSTADMAVDNGGGNAINTMPPFMNHLPMQDGTYHQQHVILGAPLAPEATAAATSAFQHPVQISGVNWNP
What is the function of this protein?
Transcription factor of the NAC family associated with the grain protein content (GPC).  Accelerates senescence and increases nutrient remobilization from leaves to developing grains.  The tetraploid cultivated wheat (T. durum) contains one additional gene coding for a functional protein (NAM-A1) and one extra pseudogene (NAM-B1) (PubMed:17124321).  Plays a weaker role in terminal senescence than NAM-A1.
What are the official names of this protein?
NAC transcription factor NAM-B2, TtNAM-B2.
What are the subcellular locations of this protein?
Nucleus.
Protein: ISPF_ECO5E
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.