PharMolix/UniProtQA huggingface dataset:
Protein: MRAY_RHOPB
Sequence: MLYWLIDFASTIPAFNVFRYITFRTGGAMVTGALFVFLCGPWIIDNLRLRQGKGQPIRSDGPQSHLSKKGTPTMGGLMVLSGLVVGTVLWANPLNPYVWIVLAVTLGFGFVGFYDDYLKVTKQSSQNGFAGRWRLLIEAVIAAAACYALVRLGRDPLSSSLVIPFFKDVAINLGWFFVGFGAFIVVGAGNAVNLTDGLDGLAIVPVMIAAASFGLISYLAGNAVFADYLQINYVAGTGELSVLCGALLGAGLGFLWFNAPPASIFMGDTGSLALGGMLGSIAVAVKHEIVLAVIGGLFVLEAVSVIVQVASFKLTGKRVFKMAPIHHHFEQKGWTEPQIVIRFWIIAVMLALAGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CHEB1_XANC5
Sequence: MTLETPVRVLIVDDSAVVRQMLTEILSRDAGIEVVGSAADPLLAREKIKRLNPDVITLDVEMPRMDGLVFLENLMRLRPTPVVMISSLTERGADTTLQALSLGAVDFVSKPKIDVARGLEGYAEEIVSKVKMAAKAKVSALNRPSAPKVTLDMQSAPVAGSALRFRTTDRLIAIGASAGGTEALRVVLEHMPADAPAVVMTQHLPASFSTAFAERLNRHSAMSVREATDGEAILPGHAYLPPGGQHLRIIRDGARWRCRIDDGPPVNRHKPAVDVLFRSVAANAGPNAVGAILTGMGDDGARGLLEMLQAGAPTLVQDEASSVVWGMPGAAYKLGAAQEVVPLDRVAERLLALSAQAR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_BRASB
Sequence: MTDPTSIKHQTTLTSGTSADFTQASEPFALFAEWFSEANKSELNDPNAMALATVDDSGLPDVRMVLMKGYDEDGFVFYSHKASQKGQELAGNPKAALLFHWKSLRRQVRIRGLVTPVTDEEADAYFATRPKQAQLGAWASKQSQPLESRFAFEQAIAKVAAQYIIGEVPRPPGWSGWRITPVRMEFWHDRPFRLHDRIEFRRDAAGQPWTKVRMYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RBR3_MAIZE
Sequence: MEGFAKPSTSSGSGVTVRASVAAASIEERFADLCKAKLGLDESTTRQAMQLLKETNNILKSSMSSLGGGSPEEIERFWSACVLYCVSRLSKAGRSKEDGSVSLCQILRASKLNIVDFFKEMPQFCIKVAHILTGLYGSDWEKRLELKELQANVVHLSLLSSYYKRAYQELFLSNDGKSSDNSSESNNQEASDYYRFGWLLFLVLRIQTFSRFKDLVTSTNELVSVLAVLIIHVPVRLRNFDIKDSSYFGKKSDRGVSLIASLCEKHHTSEDELSKALEKTNTLIMDILKKKPCPATSACQQDNLSFIDPEGLTVFKDLLQGDSLKPSLIILEKEYENAINTKGELDERMFANDEDSLLGSGSLSGGAINLPGTKRKYDVMASPAKSISSPNPMSPPRFCLSPKGNGFCNSKMAPSTPVSTAMTTAKWLRNTVSPLPSRPSGELLRFFSACDKDLTDDIAHRAGIILGAIFTSSSFGERICTSMRSASRMDAIWTEQRKMEALKLYYRVLESMCRAESQILSGNNLTSLLSNERFHRCMIACSAELVLATHKTVTMMFPAVLEKTGITAFDLSKVIEGFVRHEDTLPRELKRHLNSLEERLLESMAWEKGSSMYNSLIVARPALSVEISRLGLLAEPMPSLDAIAAHHNISLGGLPPLPFQKQERLQDKDEVRSPKRACTERRNVLVDSNSLRSPVKDIIKPKLPPLQSAFASPTRPNPAAGGETCAETGIGVFFSKISKLAAIRIRSLCERLQLPQQVLERVYSLVQQILSQQTGLFFNRHIDQIILCSIYGVAKISQLELSFKEIIFGYRKQPQCKPQVFRSVYVHWPPRSRNGKTGEDHVDIITFYNEVFIPAVKSLLVEVGPGASASPKKKEEEKGPADVGPFPESPRLARFPNLPDMSPKKVSATHNVYVSPLRSSKMDTLLSPSSKSYYACVGESTYAFQSPSKDLKAINNRLNSVSGGKKVSGRLNFDVVSDLVVASSLGSDRDAKPAADPAKTTPVKCEPSDS
What is the function of this protein?
Regulator of biological processes that recruits a histone deacetylase to control gene transcription.  May play a role in the entry into mitosis, negatively regulating the cell proliferation.  Formation of stable complexes with geminiviridae replication-associated proteins may create a cellular environment which favors viral DNA replication (By similarity).
What are the official names of this protein?
Retinoblastoma-related protein 3, ZmRBR3.
What is the protein family that this protein belongs to?
Belongs to the retinoblastoma protein (RB) family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIGB_PHOLL
Sequence: MLNLLILILFIVFSSPIVAAEIFVSNTEKNCPEWSQDKLQRETNSLMQQMAHWDQLYRQKGISEIDDEVYDQLMSELTHWQFCLKQAPHSDFPVEVFPDNKLVHPVAHTGLSKLKDKQEINRWLHGRLPVWLQPKIDGVAVTLVYQNGKLVSLISRGNGAEGVNWTAKSRYIPDIPQNIENAPPDLVLQGELFLHKEEHRQQLLGSDGARNRVAGLMMRKDHSSELKQIGLFIWSWPDGPAEMESKLRKLADMGFPLALRYSHKIEEPEQVQKLRMHYFEQPMLFATDGIVLKQEIEPKGNQWRSGSNSWAVAWKHPLRHQVTQVREVNFTIGRTGKISVVLGLDKVKLDDRQISRVNIGSVRRWRQLDVLPGDRVTLTLAGHGIPKLAQVVWRIKERQDIQPPDKQHYHALSCLTLTVGCEQQFNARLKWLGENLQMTGVSSGSWAMLTERKLVTDLTGWLALSAQQIAALPGIGDKRAQAIYSQFSKAKNQPFSYWMKGIGVPYMDKLSDNVYHWQQLEQKLAAAQLKQQLTVGQLKKLSDFVSDAQIKAIAEKLSVAGITGFDRENGVVVNPADMAQ
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: V_PI2HT
Sequence: MAEEPTYTTEQVDELIHAGLGTVDFFLSRPIDAQSSLGKGSIPPGVTAVLTSAAETKSKPVAAGPVKPRRKKVISNTTPYTIADNIPPEKLPINTPIPNPLLPLARPHGKMTDIDIVTGNITEGSYKGVELAKLGKQTLLTRFTSNEPVSSAGSAQDPNFKRGGANRERARGNHRREWSIAWVGDQVKVFEWCNPRCAPVTASARKFTCTCGSCPSICGECEGDH
What is the function of this protein?
Plays an essential role in the inhibition of host immune response.  Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway.  Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.  Efficiently blocks type I IFN signaling following infection by targeting host STAT2 for proteasomal degradation (By similarity).
What are the official names of this protein?
Non-structural protein V.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: 3MG_ARATH
Sequence: MKTPARRSKRVNQEESETNVTTRVVLRTRKTNCSKTRAARVRPDYPLTRTTSESEMKLMPPEFFQIDALDLAPRLLGKFMRRDNVVLRITEVEAYRPNDSACHGRFGVTPRTAPVFGPGGHAYVYLCYGLHMMLNIVADKEGVGAAVLIRSCSPVSGMETIQERRGLKTDKPVLLNGPGKVGQALGLSTEWSHHPLYSPGGLELLDGGEDVEKVMVGPRVGIDYALPEHVNALWRFAVADTPWISAPKNTLKPL
What is the function of this protein?
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
What are the official names of this protein?
DNA-3-methyladenine glycosylase, 3-methyladenine DNA glycosidase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_VIBVU
Sequence: MSKDFSRTQRVSQQLQKELAMILQREVRDSRLGMVTISDVEVSRDLAYAKVFVTFLCVGEQTPESCLAALREHEVHIRMMLGKRIRLRLTPEVRFYYDNTLVEGMRMSNLVTEVVNKDKIKQKDAGREDEE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_MYCTU
Sequence: MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPLVVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPSAEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGGDAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALARLGPCPQHRYSFINVRRVASGSNTAEVADGQPDPRDGTAQTGEGRWSKSSHPATMRATGRAQGT
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_POLNA
Sequence: MSNVHLISHPLVQHKLTLMRRKNASTSTFRTLLAELSNLMAYEVTRDMPLQDIEVETPLETTTGKIIDGKKLVLVSILRAGNGFLDGFLNVVPGARVGHIGLYRDPETLSPVEYYFKMPQEMQERDIVIVDPMLATGNSAIAAVDRLKQLKPRSIKFVCLLTCPEGVAALQKAHPDVDIYTAAIDRQLNEHGYILPGLGDAGDRIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: VP35_MABVM
Sequence: MWDSSYMQQVSEGLMTGKVPIDQVFGANPLEKLYKRRKPKGTVGLQCSPCLMSKATSTDDIIWDQLIVKRTLADLLIPINRQISDIQSTLSEVTTRVHEIERQLHEITPVLKMGRTLEAISKGMSEMLAKYDHLVISTGRTTAPAAAFDAYLNEHGVPPPQPAIFKDLGVAQQACSKGTMVKNATTDAADKMSKVLELSEETFSKPNLSAKDLALLLFTHLPGNNTPFHILAQVLSKIAYKSGKSGAFLDAFHQILSEGENAQAALTRLSRTFDAFLGVVPPVIRVKNFQTVPRPSQKSLRAVPPNPTIDKGWVCVYSSEQGETRALKI
What is the function of this protein?
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.
What are the official names of this protein?
Polymerase cofactor VP35, Marburg VP35, mVP35.
What is the protein family that this protein belongs to?
Belongs to the filoviridae polymerase cofactor VP35 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: YDZA_BACSU
Sequence: MLHTPIGRLRTMGFIEGMSLLILLFIAMPLKYWAGLPLAVTIVGSVHGGLFILYLLVLAYATFSVKWPLKWSAAGFIAAFVPFGNFLYDRGLRNYK
What are the official names of this protein?
Uncharacterized membrane protein YdzA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRASP_RAT
Sequence: MTLRRLRKLQQKEEATAAPDLAGRAPDSEAARAAPTPSGPPAAAAPPGAPGDELYAALEDYHPAELYRALAVSGGTLPRRKGSGFRWKNFTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQRVEMVTFVCRVHESSPAQLAGLTPGDTIASVNGLNVEGIRHREIVDIIKASGNVLRLETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGLVVKDPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAAPGGARGGSRRAKGDTDDAVYHTCFFGGAEPQALPPPPPPARAPGPGSAETPASVLCPAPRATLSRSASVRCAGPGGGGGGGAPGALWTEAREQALCGAGLRKTKYRSFRRRLLKFIPGLNRSLEEEESQL
What is the function of this protein?
Plays a role in intracellular trafficking and contributes to the macromolecular organization of group 1 metabotropic glutamate receptors (mGluRs) at synapses.
What are the official names of this protein?
General receptor for phosphoinositides 1-associated scaffold protein, GRP1-associated scaffold protein, 95 kDa postsynaptic density protein discs-large ZO-1 domain-containing protein, PSD-95 PDZ domain-containing protein, Tamalin.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Postsynaptic cell membrane.
Protein: HEMH_CAMFF
Sequence: MKKVVILLNMGGADDLSQVELFLKNMFNDPYILGIKNRKIRSVLAWLITKMRLKSATRNYTELGGKSPIGDITRSLIDKLNIKFGNENLTFDYAMNYTPPFAIDSLKKYKYADEILLFPLYPHHSRTTIVSSLDSANRAIKELSIKSNIKVINYFYKDERYNKIITSSIKEKIAEMNSSQIDLIFSSHSLPKKIIEKGDLYETHTNEHVKIISDMLAKDGVKFNSISLAYQSRLGPVEWLGPNLSEVLSNLKSKKALIYPISFCIDNSETDFELDIEYRKIADQKEFDYYEVVKAPDDSEAFVDYIAYKVKELV
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLGPB_HUMAN
Sequence: MYSEWRSLHLVIQNDQGHTSVLHSYPESVGREVANAVVRPLGQVLGTPSVAGSENLLKTDKEVKWTMEVICYGLTLPLDGETVKYCVDVYTDWIMALVLPKDSIPLPVIKEPNQYVQTILKHLQNLFVPRQEQGSSQIRLCLQVLRAIQKLARESSLMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPAFKVPDEDASLIPPEMDNECVAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRPRSDSAPPTPVNRLSMPQSAAVSTTPPHNRRHRAVTVNKATMKTSTVSTAHASKVQHQTSSTSPLSSPNQTSSEPRPLPAPRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTAITTQASMEFRRKGSQMSTDTMVSNPMFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDYVCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDRELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIGCQMEMGGGENNLKSHSRTNSGISSASGGSTEPTTPDSERPAQALLRDYALNTDSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKVMVDSGDRKRAISSVCTYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKNNEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSRLPTINKHSFRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQKLFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEIHLEQQSEEELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALKEPANSRLPPHLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNVESSRTVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINCCDDGEGSQQEVISSEDIGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILKQPSLTLELFPNHTDNLNSSQRLSPSSRMRKLPQGRPVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQEVGLKNCSS
What is the function of this protein?
Non-catalytic subunit of the heterodimeric RalGAP1 and RalGAP2 complexes which act as GTPase activators for the Ras-like small GTPases RALA and RALB.
What are the official names of this protein?
Ral GTPase-activating protein subunit beta, p170.
Protein: PURT_METM5
Sequence: MVGTPLFSNAKKILLLGSGELGKEVIIEAQRFGVECIAVDSYENAPAMQVAHRFHVIDMKDAGALREVIEREKPDLIVPEIEAINTDTLKEMETEGYHVVPTANATKLTMDREGIRRLAFEKLGLRTAKYEFAENLEELKEAVQRIGIPCIIKPIMSSSGKGQSTIKSEGDIEKSWDYAKSAARGIGTKVIVEEFIKFDYEITLLTARTAEGTRFCEPIGHIQIDGDYHESWQPHPMCAPTKAKAQEMAKKITDELGGYGIFGVELFVLDDEVIFSEVSPRPHDTGMVTMVTQKMSEFEIHARAILGLPVNVDILFPGASHVIKSEILKWAPEYEIHEASKVKDTKIRLFGKPIAKVGRRMGVALAVSDNVTKARENAEKAAHLVNIK
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: ADA1A_RABIT
Sequence: MVFLSGNASDSSNCTHPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIISLCVISIDRYIGVSYPLRYPTIVTQRRGLRALLCVWAFSLVISVGPLFGWRQPAPDDETICQINEEPGYVLFSALGSFYVPLTIILAMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGVASAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPPETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHAPSQALEGQHKDMVRIPVGSGETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV
What is the function of this protein?
This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  Its effect is mediated by G(q) and G(11) proteins.  Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity).
What are the official names of this protein?
Alpha-1A adrenergic receptor, Alpha-1A adrenoreceptor, Alpha-1A adrenoceptor, Alpha-1C adrenergic receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasm. Membrane, caveola. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK- mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes (By similarity).
Protein: SYK_LISMO
Sequence: MSNENHEELNDQLIVRREKVDTLREEGIDPFGEKFIRSISPEEIETKFADKSKEELEEAAIEVSVAGRIMTKRVKGKVGFTHIQDRFHQLQIYIRKDAIGEDAYAVFKLADLGDIIGIKGTIFRTNTGELSVKATEFTLLSKSLRPLPDKYHGLKDVEQRYRQRYLDLITNEESQNRFVMRSKILKYTRDYMDNQGFLEVETPVLHTIAGGAAAKPFITHHNALDMELYLRIALELHLKRLIVGGMDKVYEIGRVFRNEGTSTRHNPEFTMLESYAAYEDYEDVMDLVEGLVSTVCKQVNGTTEITYGEYKVDLTPNWRRIHMADAVKEYVGVDFWNVTSDEEARELAKKHDVPVTEHMTYGHILNEFFETYVEEKLIQPTFVYGHPVEISPLAKKNKEDERFTDRFELFIVGREHANAFSELNDPIDQRERFEAQMKEREQGNDEAHGMDADFLEALEYGLPPTGGLGIGIDRLVMLLTDAPSIRDILLFPTMKHRD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_PSEE4
Sequence: MVQRSKSSANWLREHFNDPFVKQAQKDGYRSRASYKLLEIQEKDRLIRPGMSVIDLGAAPGGWSQVTSRLIGGQGRLIASDILEMDSIPDVTFIQGDFTQDEVLQQILQAVGDSHVDLVISDMAPNMSGTPAVDMPRAMFLCELALDLATRVLKPGGDFLIKIFQGEGFDMYLKDVRSKFDKVQMRKPSSSRDRSREQYLLGKGFKGA
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CORC_BUCAP
Sequence: MSNKDTQGTDKINRKGFFSILLNQIFHDEPKNREELLVLIRDSEQNELIDQDTCDMLEGVMHIAKKRIKDIMIPRTQMITLKLNYNLNKCLDIIIESAHSRFPVMSRDQNYVEGFLIAKDLLPFMKHPEDAFCIKNILRSAVVVPESKSVDTMLKEFRLKRSHMAIVIDEFGAVSGLVTIEDILELIVGEIQDEYDDEEKVNIRKLKKCIFSIKALTEIKEFNDTFETNFSDEEVDTIGGLVMKAFGHLPSRGDHININGYNFKVSIADSRKVIQIHVTVPENKIPKKLEK
What is the function of this protein?
Plays a role in the transport of magnesium and cobalt ions.
What are the official names of this protein?
Magnesium and cobalt efflux protein CorC.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
Protein: RPPH_ECODH
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQENTPKPQNASAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: KDPB_SALEP
Sequence: MSRKQLALFEPVLLVQALTDAVKKLSPRAQWRNPVMFVVWAGSVLTTLLTLAMVTGQIAGSALFTGIISLWLWFTVLFANFAEALAEGRSKAQANSLKGVKKTAFARRLRAPRHDAQADNVPAAELRKGDIVLVKAGDIIPCDGEVIEGGASVDESAITGESAPVIRESGGDFASVTGGTRILSDWLVIACSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASDFIPARGVDERTLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDAIRRHVESNGGHFPADVEQNVENVARLGATPLVVVEGARVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNVMGLHSPNSAILSAVIFNALIIIFLIPLALKGVSYKPLSASAMLRRNLWIYGLGGLVVPFIGIKVIDVLLTLLGLA
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FB250_ARATH
Sequence: MKRAGGGVDFISSLPDEILHHILANTPTKLAIRTSVLSKRWKHVWYETPSISIVCNRVDPDSLNKTLSSYSTPKIKSFDVTISRDVTVPEIDTWINLALSRKAENVSLRFTSHYRFRDTFFINSSLKQLSLTLVYCILNPKCVVSWSSLRNLSLNRCKVSDDSIAKILTGCSLLESLTLNLCDRLNDLDLSKSLSLRRLEILGDRWTPERIVAPHIRYLRLENYQRPSTLVDVSSLTEANLGLSKHVLDYFTCEMETESLQYMVRQTVVKLQNIKKLTIGGIFLQILSLAELCGVTLPVFQNSISKL
What are the official names of this protein?
F-box protein At5g03100.
Protein: MINC_BORPA
Sequence: MNTESLALDFKSATLYAIRVVLHDADTTRLRAALDKRMADAGSFFENEPVVIDATRVDAPVDWPALLQALADHNLPPIGVVAEDANLQGARDAGLVPVELSTPVARAPQVIDTAPPNDVATPVPSVPEATAEAAAKAGPQDDEADGEQADEAPAHNPESVPTRAARETTEANRPTATPPQSSSALVITKPLRSGQRVYARHTDLIVIGMVSQGAEVIADGNVHVYGPLRGKAMAGARGDTSARIFTTQLDAELLAVAGVYRVVEDKLDRALHNQPALVRLDGDTLRIEALKG
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: PSMD1_PONAB
Sequence: MITSAAGIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAALVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEGEKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFEKTILESNDVPGMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKDSDSMETEEKTGSAFVGKTPEASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMILKNTKDAVRNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASNDIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQSRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLNKDLKMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKMEVDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPETCRYQPFKPLSIGGIIILKDTSEDIEELVEPVAAHGPKIEEEEQEPEPPEPFEYIDD
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 1, 26S proteasome regulatory subunit RPN2, 26S proteasome regulatory subunit S1.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S1 family.