PharMolix/UniProtQA huggingface dataset:
Protein: RDRP_BPFR
Sequence: MSKSTKKFNSLCIDLSRDLSLEVYQSIASVATGSSDPHSDDFTAIAYLRDELLTKHPNLGDGNDEATRRSLAIAKLLEANDRCGQINRDGFLHDATASWDPDVLQTSIRSLIGNLLSGYSSQLFRHCTFSNGASMGHKLQDAAPYKKFAEQATVTPRALKAAVLVKDQCSPWIRHSHVFPESYTFRLVGGNGVFTVPKNNKIDRAACKEPDMNMYLQKGVGGFIRRRLKTVGIDLNDQTINQRLAQQGSRDGSLATIDLSSASDSISDRLVWSFLPPELYSYLDMIRSHYGYVNGKMIRWELFSTMGNGFTFELESMIFWAIVRATQIHFRNTGTIGIYGDDIICPTEIAPRVLEALSFYGFKPNLRKTFTSGSFRESCGAHYFRGVDVKPFYIKKPITDLFSLMLILNRIRGWGVVNGIADPRLYEVWEKLSRLVPRYLFGGTDLQADYYVVSPPILKGIYSKMNGRREYAEARTTGFKLARIARWRKHFSDKHDSGRYIAWFHTGGEITDSMKSAGVRVMRTSEWLQPVPVFPQECGPASSPQ
What is the function of this protein?
This is the catalytic subunit of the viral RNA-dependent RNA polymerase complex.  This complex is involved in viral RNA replication that produces (+)-stranded genomes via a complementary, (-)-stranded intermediate.
What are the official names of this protein?
RNA-directed RNA polymerase beta chain, RNA replicase beta chain.
Protein: CBRA_ECO24
Sequence: MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSKPCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHAFDLWMKSLIPTSVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSMVRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAYPMKDGQTRFTTLKEKMSAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAGFISASSLEGISYALDSADILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTAPALRKWIMRSGMAHIPQLKD
What are the official names of this protein?
Protein CbrA.
What is the protein family that this protein belongs to?
Belongs to the CbrA family.
Protein: ENO_SYNY3
Sequence: MLSKVPATIEEIAAREILDSRGRPTIEAEVRLESGAHGIAQVPSGASTGSFEAHELRDGDPKRYDGKGVEKAVRNVTEKIAPVVEGLDAFDQMAVDQAMIDRDGTDNKKELGANAILGVSLATAKAAAAELAIPLYRYLGGPLANVLPVPMMNVINGGAHADNNVDFQEFMIMPVGAETFKEALRWGAEVFAVLGKVLKERKLLSGGVGDEGGYAPNLTSNQQALDILIEAIEQAGYKPGSQIALAMDIAASEFFKNGQYEYDGGSHSPQEFIDYQAKLVSQYPIVSIEDGLHEDDWESWKGLTTSLGTKTQLVGDDLMVTNPVRLQKSIDLGVANAILIKLNQIGTLSETLETISLATRHSYRSVISHRSGETEDTTIADLAVATRVGQIKTGSLCRSERVAKYNRLLRIEDELGDRAVYAPKIGLGPKHS
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: FADJ_SALCH
Sequence: MTTTSAFMLNVRLDNVAVVAIDVPGEKVNTLKAEFAAQVRAILKQIRENKALQGVVFISAKADNFIAGADINMIGHCQNAQEAETLARQGQQLMAEIQALPVPVIAAIHGACLGGGLEMALACHRRICTDDVKTVLGLPEVQLGLLPGSGGTQRLPRLVGVSTALDMILTGKQLRARQALKAGLVDDVVPQTILLEAAVELAKKERLAQRTLPVRERILAGPLGRALLFRLVRKKTAQKTQGNYPATERIIDVIETGLAQGSSSGYDAEARAFGELAMTPQSQALRAIFFASTKVKKDPGSDAPPGPLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISGSTDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAANAARPEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKKQGKTPIVVSDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVASILNDDRKGRKNGRGFYLYGEKGRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVIRSARDGDIGAVFGIGFPPFLGGPFRYMDALGPGEMVATLQRLAALYGPRYAPCEQLVRMAERREHFWTNGETDQGN
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STS1_AJECN
Sequence: MNSLLATPPVPPHFYEHCRLSPSRSMSSTNPSGNRKRKAEDDYLPSDHDTRMSASPSNSPAFPPRPLPASRQIKRPRPNISGRPLSLSRLLETLDTDALRSVLRSMCDRHPELATEVVHTAPRPSVSSALQVLNNYQSALHSSIPLGGNSSSDYAYNRVRQHIVNLLDALSDFTPHFLPPNESQTSTALSYLDGATEILHRLPRWDTPQNNLEKDAAYEEMAKAWILVIREAGKRGGGIQLQYGGWDEKLSKHNQTAGGKLQDAVDVLSSNLGWMGTSQDLSNNQGVDTSSIRQQLLSGTYGSGMPLKVGRW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome STS1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYB_PEA
Sequence: MTIRNQRLSLLKQPISSTLNQHLIDYPTPSNLSYWWGFGSLAGICLVIQIVTGVFLAMHYTPHVDLAFNSVEHVMRDVEGGWLLRYMHANGASMFLIVVHLHIFRGLYHASYSSPREFVRCLGVVIFLLMIVTAFTGYVPPWGQMSFWGATVITSLASAIPVVGDTIVTWLWGGFSVDNATLNRFFSLHHLLPFILVGASLLHLAALHQYGSNNPLGVHSEMDQISFYPYFYVKDLVGWVAFAIFFSIWIFYAPNVLGHPDNYIPANPMPTPPHIVPEWYFLPIHAILRSIPDKSGGVAAIAPVFICLLALPFFKSMYVRSSSFRPIHQGIFWLLLADRLLLGWIGCQPVEAPFVTIGQIPPFVFFLFFAITPIPGRVGRGIPNYYTDETDQ
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL24_PSEA8
Sequence: MQKIRRDDEVIVIAGKDKGKRGKVLKVLADDRLVVGGVNLIKRHTKPNPMLGQQGGIVEKEAPLHVSNVAIFNTETSKADRVGFKVEDGKKIRVFKSTQKPVQA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RBFA_PECCP
Sequence: MAKEFSRTQRVAQEMQKEIAIIIQREVKDPRIGMATVSGVEVSRDLAYAKVFVTFLNDNEPEQVKTALKALQDASGFIRTLVGKAMRLRVVPALTFSYDNSLVEGMRMSNLVTNVVRNDTERRSVTGEDQED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIM17_YEAST
Sequence: MIPRTRTLLQSKIPITRYFARCWAPRVRYNVCRTLPAAALHTNIIAHNEVKKDDKKVHLGSFKVDKPKMMIAFTCKKCNTRSSHTMSKQAYEKGTVLISCPHCKVRHLIADHLKIFHDHHVTVEQLMKANGEQVSQDVGDLEFEDIPDSLKDVLGKYAKNNSENASQLPHPSQK
What is the function of this protein?
Involved in protein import into mitochondria.  Acts as a Hsp70-specific chaperone that prevents self-aggregation of the matrix Hsp70 chaperones SSC1 (mtHSP70) and SSQ1, thereby maintaining their function in mitochondrial protein import and Fe/S protein biosynthesis.  May act together with PAM18 as co-chaperone to facilitate recognition and folding of imported proteins by SSC1 in the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial protein import protein ZIM17, Mitochondrial import inner membrane translocase subunit TIM15, mtHsp70 escort protein 1, mtHsp70-associated motor and chaperone protein TIM15/ZIM17, MMC.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=Soluble matrix protein loosely associated with the inner membrane.
Protein: PG058_VARV
Sequence: MKHKVYSEGLEISTDFNSIISQLSTSDMDIEIDEDNITELLNILTELGCDVDFDEDFSDITDDVLESLMEQDM
What are the official names of this protein?
Protein OPG058, Protein F14.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG058 family.
Protein: NADK_CHRVO
Sequence: MERLFKHICLVARHSKPGITPALMQLANHLAAGGATVLIDKESVTPDEANGYPLIDRTDMGKLADLCIVLGGDGTMLSIARLLAPYRVPLVGINQGRLGFMTDIPLHEMLDSVDAILHGKFVPEDRILLQAAVVREDAEVASALAFNDVVFSRGAVGSMIEFEVFIDNQFVYSQRSDGLIVSTPTGSTAYSLASGGPILHPTLQAIALVPICPQSLSNRPIAVNDSCEVEFMLTRGLDARVHFDGQLHCDLMEMDRVLIRRYRNPLRILHPEGYNYYDMLRHKLHWGERLI
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMBR_PIG
Sequence: MPPKSLSNLSQTAGVNQSGFFPGASERDFLPATDRTTAEFVIRCVIPSLYLLIITVGLLGNIVLVKIFLTNSAMRSVPNIFISNLAAGDVLLLLTCVPVDASRYFLDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDIQTSGAVLWTCVKAGGIWVVSVLLAVPEAVFSEVARIDGLDNGSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLGIISVYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFCNSCVNPFALYLLSESFRKHFNNQLCCGRKSYRERSPSYLLSSSAVRMTSLKSNAKNIVTNSVVPNGHSVKQEMAL
What is the function of this protein?
Receptor for neuromedin-B (By similarity).  Contributes to the maintenance of basal sigh rate through signaling in the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity).  Contributes to the induction of sneezing following exposure to chemical irritants or allergens which causes release of NMB by nasal sensory neurons and activation of NMBR-expressing neurons in the sneeze-evoking region of the brainstem (By similarity).  These in turn activate neurons of the caudal ventral respiratory group, giving rise to the sneezing response (By similarity).  Contributes to induction of acute itch, possibly through its activation on dorsal root ganglion neurons by the NMB peptide (By similarity).  Plays a role in the innate immune response to influenza A virus infection by enhancing interferon alpha expression and reducing expression of IL6 (By similarity).  Plays a role in CSF1-induced proliferation of osteoclast precursors by contributing to the positive regulation of the expression of the CSF1 receptor CSF1R (By similarity).
What are the official names of this protein?
Neuromedin-B receptor, NMB-R, Neuromedin-B-preferring bombesin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HBEAG_HBVD6
Sequence: MQLFHLCLIISCTCPTVQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGVNLEDPASRDLVVSYVNTNMGLKFRQLLWFHISCLTFGRETVIEYLVAFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells.  This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.
What are the official names of this protein?
External core antigen, HBeAg, Precore protein, p25.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus precore antigen family.
What are the subcellular locations of this protein?
Secreted. Host nucleus.
Protein: RIMP_AGRVS
Sequence: MSEHVPADEAPEPRLITETGLDRRIADIIEPVIVELGFELVRVRILNQNGMTLQIMAERKDGTMTVEDCEELSMAISPVLDVEDPVDKEYHLEVSSPGIDRPMVRASDFTRWQGNLLKCETSILIDNRKRFRGKIADVTPDGFILERDQVAYGEEPRLTIPFTALAEAKLILTDDLVRDALRADKQAKAAAEAANQNDETGEDQ
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB1_BACLD
Sequence: MSAVTAVKPEDVYQINDLNLWYGEHHALKNINLTIPEYEITAIIGPSGCGKSTFIKTLNLMINMVPNVKMTGEISYNGTNVLNSKVDLVELRKKVGMVFQKGNPFPQSIFDNVAYGPRIHGLKNKKELNERVEKALVDVALWDEVKDRLHSQALGLSGGQQQRLCIARALATNPDVLLMDEPTSALDPVSTLKIEELMLKLKEKYTIAIVTHNMQQASRISDQTAFFLMGELIECNDTVKMFSSPDDHRTKDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 1, ABC phosphate transporter 1, Phosphate-transporting ATPase 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GSA_PSEMY
Sequence: MSRSEILFANAQKHIPGGVNSPVRAFRSVGGTPLFFKHAEGAYVVDEDDKRYVDYVGSWGPMILGHSHPDVLDSVRRQLQHGLSYGAPTALETEMAELVCSLVPSMEMVRMVSSGTEATMSAIRLARGYTGRDSIIKFEGCYHGHSDSLLVKAGSGALTQGVPNSAGVPAAFAKHTLTLPFNDIDAVAECLAQVGKEVACIIVEPVAGNMNCVPPAPGFLEGLREQCDKHGVVLIFDEVMTGFRVALGGAQAHYGVTPDLTTFGKIIGGGMPVGCFGGKRAIMECIAPLGPVYQAGTLSGNPLAMAAGLTTLKLISRPGFHTELSDYTTRMLDGLQQRADAAGIPFVTTQAGAMFGLYFSGADDIVTFADVMASDSARFNRFFHLMLEGGVYLAPSAFEAGFTSIAHGDKELEITFAAAERAFAELKKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR1_KARBO
Sequence: AQSFLRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-1, FMRFa-1.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: LUTB_BACC7
Sequence: MSMKISEKKFNDRVGDGIQDSFMRGAVSSAQTRLYTNRLKAADELGNWEEWRELGEEIRQHTLENLDYYLMQLSENVSKRGGHVYFAKTKEEAAKYIQDVAKKKQAKKVVKSKSMVTEEISMNHALEEIGCEVLESDLGEYILQVDNDPPSHIIAPALHKNRTQIRDVFKEKLGYENSDDPYEMTKFVRKQLREKFMDAEIGVTGCNFAVANTGSLCLVTNEGNADLVMSIPKTQIAVMGMERMVPTMEELDVLVGLLCRSAVGQKLTSYVTVAGPIQEEEVDGPEEFHLVVVDNGRSQILGSEFRQVLQCIRCAACVNVCPVYRHVGGHSYGSIYSGPIGAVLTPLLGGYDDYKELPYASSLCGACTEACPVKIPLHDLLLKHRQVIVEQEGRAPLAEKLAMKMFSMGASSAALYKMGSKMAPAAMSPFTSGNRVSKGVGPLKNWTDIREFPAPSKERFRDWYKDHKKGGDK
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.  Has probably a role as an electron transporter during oxidation of L-lactate.
What are the official names of this protein?
Lactate utilization protein B.
What is the protein family that this protein belongs to?
Belongs to the LutB/YkgF family.
Protein: F16PA_POLNS
Sequence: MKTGEIPLSSSTYINFKQYLASVKPAGAALPTGLQDLLIAVVNTCSKLSHEVAQGALIGLLGPAGTGNVQGEVQQKLDIIANDLLIDGVQGCKSLAGLASEEMELPVPVQGTGDYLLLFDPLDGSSNIDVNVSIGTIFSVLKKQDPAAPLQTSDFLLSGRHQVAAGYVVYGPQTTMALTLGDGVVMFTLNKVTGEFLLIKDSVTISHSTKEFAINMSNMRHWADPVRRYVEECLAGVSGARDKDFNMRWIASMVADVHRVLSRGGVFMYPWDQREPHKPGKLRLMYEVNPMSFLVEQAGGVSTNGTDLIMDLQPTDLHERVSVMLGSKEEIDRIQHYHS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPH_THEMA
Sequence: MSELDAREIIEMIAKAKKKTPIVAYIKGDLAGIDFSSFKFFGDERFGILFGEYEDFKKLLEEHREKIEDYHLEVKARNSALPLADLTKYKARIEPGAIIRDMVEIGEGAVIMMGAVINVGAVIGEGTMIDMNAVVGGRAIIGKKCHIGAGAVIAGVIEPPSAKPVVIEDEVLVGANAVILEGVTVGKGAVVAAGAVVTKDVPPYTVVAGVPARVIKQIDEKTKEKTKIVDELRNLE
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: RPP30_MOUSE
Sequence: MAAFADLDLRAGSDLKALRGLVETAAHLGYSVVAINHIVDFKEKKREIEKPIAVSELFTTLPIVQGKSRPIKILTRLTIIVTDPAHCNVLRATSSRVRLYDIVAVFPKTEKLFHVACTHLDVDLVCITVTEKLPFYFKRPPVNVAIERGLGFELVYGPAIRDATMRRYTISNALNLMQICKGKNVILSSAAERPLEIRGPYDVANLGLLFGLSENDGKAAVSTNCRAVFLHGETRKTAFGIISTVKKPRPSEADDESLPVCKKAKCEG
What is the function of this protein?
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.  Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences.
What are the official names of this protein?
Ribonuclease P protein subunit p30, RNaseP protein p30, RNase P subunit 2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 3 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ISCA_CROS8
Sequence: MSITLSDTAAARVNAFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDAPQPEDTVFEDKGVKVVVDGKSLQFLNGTQLDFVKEGLNEGFKFTNPNVKDECGCGESFNV
What is the function of this protein?
Is able to transfer iron-sulfur clusters to apo-ferredoxin.  Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically.  Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB.
What are the official names of this protein?
Iron-binding protein IscA, Iron-sulfur cluster assembly protein.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: PAL2_SOLTU
Sequence: MAPSIAQNEHINGEVKEVLWNLCKKQNYLPLNWEMAADSLRGSKLDQVKKMVDEFRKPIVKLGGETLTVAQVASIANVDNKSNGVRVELSESARAGVKASSDWVMDSMSKGTDSYGVTTGFGATSHRRTKNGGTLQKNLIRFLNAGVFGIGTESTHTLPHSATRAAMLVRINTLLQGYSGIRFEILEAITKLINSNISPCLPLRGTVTASGDLVPLSYIAGLLTGRPNSKAVGPTGSKLDAEEAFRVAGVTGGFFELQPKEGLALVNGTAVGSAMASIVLFESNILAVMFEVLSAIFAEVMNGKPEFTDYLTHKLKHHPGQIEAAAIMEHILDGSSYVKAAQKLHEMDPLQKPKQDRYALRTSPQWLGPQIEVIRAATKMIEREINSVNDNPLIDVSRNKAIHGGNFQGTPIGVSMDNTRLALASIGKLMFAQFSELVNDYYNNGLPSNLTAGRNPSLDYGFKGAEIAMASYCSELQFLANPVTNHVQSAEQHNQDVNSLGLISARKTAEAVDILKLMSSTYLVALCQAIDLRHLEENLKSVVKNTVSQVAKRTLTIGVLGELHPARFCEKELLRVVDREYLFAYADDPC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase 2.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_SHEHH
Sequence: MDKVKIALQYIMPKHLLSRLVGKLAAAEMGSVTTAAINWFIKQYKIDMSEAAEPEATAYSCFNDFFTRALKPGIRPLCDDNDYIVHPVDGAVSQLGPIKEGRIFQAKGHDYSSLALLGDQADDAKRFEGGDFATIYLAPKDYHRIHMPIKGTLSKMTYVPGELFSVNPLTAENVPGLFARNERVVAIFETEIGPMAMVLVGATIVASIETVWAGTVTPPTGKKVFTWDYPTEGPNALTLEKGAEMGRFKLGSTVVMLFAKDALDEFADGVEPRSVTRMGQAFAKIED
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HSLV_CAMJE
Sequence: MFHATTILAYKGKNKSVIGGDGQVSFGNTVLKGNAVKIRKLNNGKVLAGFAGSTADAFNLFDMFENLLQSSKGDLLKAAIDFSKEWRKDKYLRKLEAMMLVLDRNHIFLLSGTGDVVEPEDGQIAAIGSGGNYALSAARALAKHTDLDEEELVKSSLQIAGEICIYTNTNIKTYVIEDEK
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_SALAR
Sequence: MSVIKMTDLDLAGKRVFIRADLNVPVKEGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDEALSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADVACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFVAAQGHSVGKSLYEADLVDEAKRLLTTCDIPVPTDVRVATEFSETAPATLKSVNDVKEDEQILDIGDASAQQLAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRE_DICDI
Sequence: MSKVLAIVTGASKGFGKAIAQEIVKCNPNKNQLIDLVLFARSLDGLKSTKESIETISTNAKVIDLQSLDMSNIPDVELKFKSVLENIKWEEYSKICFFNNHGTLYHLGRIEDFSDFKNIQKDNDTNTTSFVVTTSLLVKKLKELGSQYSSEVTIVNSSSLCAIKAFPTWSLYCSSRAYRDMFFQALSLEYKLNDKFKVLNYSLGVLDTDMQSQVREECSEDDKSFYVGLKNDGKLINPNRSASICSNLVYSHKFETGSHLDYYDLDK
What is the function of this protein?
Catalyzes the production of D-threo-tetrahydrobiopterin (tetrahydrodictyopterin or DH4), also known as dictyopterin, and in a much smaller amount that of it's stereoisomer L-erythro-tetrahydrobiopterin ((6R)-L-erythro-5,6,7,8-tetrahydrobiopterin or BH4) (PubMed:16527408).  Prefers 1-oxo-2-D-hydroxypropyl-tetrahydropterin to 6-pyruvoyltetrahydropterin (6-pyruvoyl-5,6,7,8-tetrahydropterin) as a substrate, thereby maintaining dominant production of DH4 over BH4 in sufficient supply of an aldose reductase-like enzyme (PubMed:16527408).  DH4 represents more than 95% of the total tetrahydrobiopterin production.  It has a direct antioxidant function to protect mitochondria against oxidative stress (PubMed:17976377).  Essential for the last step of BH4 synthesis (PubMed:10987137, PubMed:15896778).  Also catalyzes the conversion of sepiapterin to L-erythro-7,8-dihydrobiopterin, which is then reduced to BH4 by dihydrofolate reductase, constituting the salvage pathway of BH4 (PubMed:10987137).
What are the official names of this protein?
Sepiapterin reductase, SPR, SR.
What is the protein family that this protein belongs to?
Belongs to the sepiapterin reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_DELAS
Sequence: MKLILLGAPGAGKGTQAAFICQKYGIPQISTGDMLRAAVKAGTPLGQQAKAVMDAGQLVSDDLIINLVKERIAQADCANGFLFDGFPRTIPQADAMKAAGVKLDYVLEIDVPFDAIIERMSGRRSHPASGRTYHVKFNPPKVEGQDDVTGEPLVQREDDKEETVKKRLDVYSSQTRPLVDYYRAWAEKEAAAAPKYRAISGLGSVEDITQRALAALAE
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.