PharMolix/UniProtQA huggingface dataset:
Protein: RPO1C_METTH
Sequence: MQDIIGKIEDYSSKNGILLPDPVVEYVARIADEEKLKEPELQEMVRLFSRIAERNQGLDDDELLDAVEDDYQRILKVQELVKRKRARFPPKLIEDIAEVMKKHELSDDELDELIRRVRRAYDRARVEAGEAVGTVAAQSVGEPGTQMTMRTFHYAGVAELNVTLGLPRLIEIVDARKKISTPTMSIYFEGDLRYDEEFVRRKANKIGKSTLNDVLKNFSIQYADMSVVAELDEEKIQEKHLEYDEILAKVEKTFKKVEIDNNILRFEPPKPTIRELRLLADKVRKLQISGVKNIGKVVIRKEDDEWVIHTEGSNLGAVLKEEGVDKVRTTTNDIHEIETVLGIEAARNAIIHEAKRTMEEQGLTVDIRHIMLVADMMTADGSVKSIGRHGISGEKASVLARASFEETGKHLLRASIRGEVDHLTGIIENIIIGQPIPLGTGSVSVVMKERK
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTRA_BRUAB
Sequence: MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVAGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAVSGNQSYIETVWGRGYVLREPDAEMRESA
What is the function of this protein?
Component of a regulatory phosphorelay system that controls B. abortus cell growth, division, and intracellular survival inside mammalian host cells.  This signaling pathway is composed of CckA, ChpT, CtrA and CpdR.  CtrA is a response regulator substrate of ChpT (By similarity).  When phosphorylated, directly regulates the expression of ccrM.  Is also probably involved in the transcriptional regulation of rpoD, pleC, minC and ftsE genes (PubMed:11929544).
What are the official names of this protein?
Cell cycle response regulator CtrA, Cell cycle transcriptional regulator A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABA_YERPN
Sequence: MVDKRESYTKEDLEASGRGELFGAGGPPLPAGNMLMMDRIVKMIEDGGSHNKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPDAKKVTYRINFKRVIMRKLIMGVADGEVLVDGKVIYTATDLKVGLFKDTNAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y055_ARCFU
Sequence: MKFACRAITRGRAEGEALVTKEYISFLGGIDKETGIVKEDCEIKGESVAGRILVFPGGKGSTVGSYVLLNLRKNGVAPKAIINKKTETIIAVGAAMAEIPLVEVRDEKFFEAVKTGDRVVVNADEGYVELIE
What are the official names of this protein?
UPF0107 protein AF_0055.
What is the protein family that this protein belongs to?
Belongs to the UPF0107 family.
Protein: PSBM_MARPO
Sequence: MEVNILAFIATALFILIPTAFLLILYVQTASQNS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MDH_XANCB
Sequence: MKAPVRVAVTGAAGQIGYALLFRIASGEMLGKDQPVILQLLELSNEKAQAALKGVMMELEDCAFPLLAGMVGTDDAEVAFKDIDVALLVGARPRGPGMERKDLLLENAKIFTAQGAALNKVAKRDVKVLVVGNPANTNAYIAMESAPDLNPKNFTAMLRLDHNRALSQLSLKLGKPVGGIEKLVVWGNHSPTMYPDYRFATSDGASIGDAINDQEWNAGTFIPTVGKRGAAIIEARGLSSAASAANAAIDHVRDWVLGSNGKWVTMGVPSDGSYGIPEGVIFGFPVTTENGQYTLVKDLPIDDFSQKYIDKTLAELEEERSGVSHLLG
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: DERL2_MOUSE
Sequence: MAYQSLRLEYLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPVGFNFLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRRNPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRILKTPSILRTIFDTPDEDPNYNPLPEERPGGFAWGEGQRLGG
What is the function of this protein?
Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal glycoproteins, but not that of misfolded nonglycoproteins.  May act by forming a channel that allows the retrotranslocation of misfolded glycoproteins into the cytosol where they are ubiquitinated and degraded by the proteasome.  May mediate the interaction between VCP and misfolded glycoproteins.  May also be involved in endoplasmic reticulum stress-induced pre-emptive quality control, a mechanism that selectively attenuates the translocation of newly synthesized proteins into the endoplasmic reticulum and reroutes them to the cytosol for proteasomal degradation.
What are the official names of this protein?
Derlin-2, Degradation in endoplasmic reticulum protein 2, Der1-like protein 2, F-LANa.
What is the protein family that this protein belongs to?
Belongs to the derlin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RSMJ_PSEA6
Sequence: MAPVVTVPENASPELVEKAKNLASVWQLNFDGNVRHGLVLMQSEAHLALKQLDEPKVGEVLVDFASDALTFRRLHGGGKKEAVAKAVGLKGQSEWRVLDATAGLGRDAFVLASLGCRVDMIERSPVVAALLADGLERAHHSAELSAWLPQRMRLHHGIAVDLMANWCNEPANLAPDVVYLDPMFPHRKKSAAVKKEMRLFQQLLGPDEDADGLLAPALALAKKRVVVKRPAGAPFLAQQKPHIEMQGKANRFDVYLIN
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STM1A_XENLA
Sequence: MCDSDIKVKQLEKRASGQAFELILSPPSMDAAPDLSITSPKKKECSLEEIQKKLEAAEERRKLHEAEILKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTTKMETIKENREAQIAAKLERLREKDKKVEEIRKGKECKEPSEK
What is the function of this protein?
Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules.  It prevents assembly and promotes disassembly of microtubules (By similarity).
What are the official names of this protein?
Stathmin-1-A, Stathmin clone XO35.
What is the protein family that this protein belongs to?
Belongs to the stathmin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TUSC_BUCAT
Sequence: MKMVAFVFSHAPHGISLGREGLDAIFSISSIFKKISVFFIGDGVLQLIKNQQPEHILARNYTSSFSILSLYNIKDLYCCKASLLERGLNNNNNFILNIDVLDSYNLRLKLDNYDAIINF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 5NTD_PSEAE
Sequence: MRDAALRYPNILFDLDGTLTDPREGITRSVQFALARLGIDEPDLARLEHFIGPPLLQCFMQTYGFDEARAWEAVNHYRERFRVTGLYENRVFDGIPELLEALVGRGHTLYVATSKPGVFAREIARHFAFDRHFKAIYGSELDGTRTHKEELIRHLLDSEGLAAEHCLMIGDRMHDLLGASRNGVACIGVGYGFGSEDELRAHQPTHYCADLAALRQVLESH
What is the function of this protein?
Specifically dephosphorylates nucleoside 5'-monophosphates to nucleosides and inorganic phosphate.  Displays high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP.
What are the official names of this protein?
5'-nucleotidase, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: PYRG_LEVBA
Sequence: MTKYIFVTGGVVSSLGKGIVAASLGRLLKNRGLNVTIQKFDPYINVDPGTMNPYQHGEVFVTDDGTETDLDLGHYERFIDNNLNKYSNVTTGKIYSEVLEKERHGDYLGATVQVIPHITGMIKEKIMRAGKTLGADFVITEIGGTVGDIESQPFLEAIRQMKAEVGDENVVYIHTTLVPYLHAAHEMKTKPTQHSVRELRSIGIQPNILVVRTEAPITDDMRKKIALFCDVDPSAVVESMDVPTIYSIPLRLQDQGLDQIVLDHFGVQAPKADMTAWAQMVDHMQHLSRTIKIALVGKYVALHDAYISVAEALQHAGYPVDANIDLQMIDAEKITDDNVQDVLGSADGIIVPGGFGDRGIEGMITAIKYAREQDVPFLGICLGMQVASIEFARDVLGYADANSTEMNPDTSHKIIDLMADQADVHEMGGTQRLGLYPCKLKAGSRAAAAYDNQEMIQERHRHRYEFNNQYRDEMTAKGLVFSGTSPDDHLVEVIELPEKKFFVAAQYHPEFLSRPNRPEGLFRDFVAAASREVKD
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RS5_ACTSZ
Sequence: MSNIEKQTGELQEKLIAVNRVSKTVKGGRIMSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNDGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVRNVLSKAYGSTNPINVVRATIDALANMKSPETVAAKRGKTVDEILG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HEM3_BACHK
Sequence: MRKIIVGSRKSKLALTQTNWFIDQLKALGLPYEFEVKEIVTKGDVILDVTLSKVGGKGLFVKEIEHALLTKEIDMAVHSMKDMPAVLPEGLMIGCTPKRVDPRDAFISKSGASFKELAEGAILGTSSLRRSAQLLAARPDLQVKWIRGNIDTRLRKLKEEDYDAIILATAGLQRMGWDDEVITEHLDETLCVPAVGQGALAIECREDDKDLLQLLAHINDAVTERTVAAERVFLHKLEGGCQVPIAGYATLTENDAIELTALVGSMDGSILLKETVVGTDPEKVGLEAADRLIKQGAKELILAANKGQQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: EXOR_RHIME
Sequence: MRAGELKSLRVAVLGMSLAVGATAAGPARAFDPGAGVTKESGPFALFKFGFSAYKSGRKDEAVEAYRYAAEKGHTGSRWALANMYAYGDGVAENDLEAFKIYSEIAQQGVEPGSEDTGYFVNALISLAGYYRRGIPDTPVRSDLSQARQLYFQAASTFGVAEAQFQLARMLLSGEGGSVNVQQAKKWLNRARKNGHAGAMGVFGNVIFQEGQTARGLAYMTAALGQCSPKDRPWLQAMQEQAFSLATEDDRRVAITMSQNMHLQNDDD
What is the function of this protein?
Negatively modulates exopolysaccharide (EPS) biosynthesis.
What are the official names of this protein?
Exopolysaccharide production negative regulator.
Protein: YN55_SCHPO
Sequence: MRLEAKTKLSSKAKEPINVVKYNRTGKYVLAAGNERVVRLWNVKSGACIHEYAGHGHEILDLDLVYDSTKFASCGGDKFIQVWDVNTGKVDRRLGGHLAQINTIRYNEDSSILASGSFDSKVRLWDCRSNSFSPIQVLADAKDSVSSIDIAEHLIVTGSTDGTLRTYDIRKGTLSSDYFSHPITSVKTSKSASFSLISSLNSSIHLLDQETGKILKSYIGLKNMEYRVRSSFNQSETIVFSGSEDGKVYLWDLENETQITSTSVVGTPIVTDISCHPTMDDFIIATVHGDLFIYQYN
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C713.05.
What is the protein family that this protein belongs to?
Belongs to the WD repeat MORG1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: HBB_PTEAL
Sequence: VHLSGEEKAAVTGLWGKVKVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSASAVMGNPKVKAHGKKVLDSFSEGLQHLDNLKGTFAKLSELHCDKLHVDPENFRLLGNVLVCVLARHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: EFP_BACMK
Sequence: MISVNDFRTGLTISVDNALWQVMDFQHVKPGKGAAFVRSKLRNLRTGSVQEKTFRAGEKVEKAHIENRRMQYLYASGESHVFMDNETYEQIELGENQIERELKFLKENMGVSIMTYQDEVLGVELPNTVELTVSETEPGIKGDTASNVTKPAKLETGLVVQVPIFINEGEMLIINTGEGKYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGALD_NEOFI
Sequence: MESIVWLLLLSPALVAGSLHPRIDNGLAKTPQMGWNSYNYYSCSPNEAIVRSNAKALVDLGLADLGYRYVTTDCGWSVADRLPNGTLTWNETLFPSGFPAMGKYLHELGLLFGVYGDSGTKLCGSPPDQVGSLYHEEQDAKTFAEWGADSLKYDNCYSDAATNYPNVNYEPSTSPRPRYEIMSSALARVGRPILFQICEWGIDFPALWAPALGSSWRIGNDIIPEWRSIFRTLNQAVPNTDFAGPGQWADLDMLYVGNGVFSLPEEQTHFSLWAILKSPLTIGAALKDDDTSINQASLEVLKQKDVIGFNQDALGVSASLKRRWSDEGYEVWSGPLSGNRTVVAVINWRDESRDLTLDLPDVGLQYAQVARNIWGKTVVRDVRTSYTAGVAGHGTMLLELQGTIPSGLYPAKIFAKSTDQKTTFESIYAATTSANYELAITFSRPSTETVTITTSSGQTISISGKSGRIALTAGSNTITIQHKTPIESIQITPPTGTYYANTVFNVTGSAKHTTCGSGCSPVGSKIGDLSPNSNAYTSIPATTVGSKYLAIDYINNEVAFSSSWGWGSNSRNLTVSVNDGAPVRLEVPLSGRHSELFSPGKGWWDTATLGVLTSGWKKGENKVVFGNQGGEDGFQTYAADFVGVRILD
What is the function of this protein?
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides.
What are the official names of this protein?
Probable alpha-galactosidase D, Melibiase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYT_PSEAU
Sequence: MVHSQLPVAGPLRLLCALLLLPSATMIPGGLSPRSVTDPDVQEAAEFAVQEYNALSANAYYYKQLRIVEAQSQVVSGAKYYLTMELMKTKCAKTTGKPKVYKEIQNCELPPKAQQEKLTCHFQVWSRPWLGKIELTKMSCN
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as a housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MED21_NEOFI
Sequence: MADILTQLQTCLDQLATQFYATIGYLSTYHDNSPAIPHPDVPDAAPALAKIPKNSTAPPVPAGAPVPAQSQASPPAQNPAHGAAGAGTSVGEGGQTPGPAAGAGADPNLPAPDSPRTFASRQRELARDLIIKEQQIEYLISVLPGIDSSEAEQEKRIRELEGELRRVEEERELKMRELKRLRRTLENVLRAVETGLYGDRELLERYS
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FOLD_HELPY
Sequence: MPNRGVVLLDGQALADNIEKDLKHKIQIITAQTHKRPKLAVILVGKDPASITYVNMKIKACERVGMDFDLKTLQENITEAKLLSLIKDYNTDQNISGVLVQLPLPRHIDTKMILEAIDPNKDVDGFHPLNIGKLCTQKESFLPATPMGVMRLLEHYHIEIKGKDVAIIGASNIIGKPLSMLMLNAGASVSVCHILTKDISFYTQNADIVCVGVGKPDLIKASMLKKGAVVVDIGINHLNDGRIVGDVDFNNVQKVAGFITPVPKGVGPMTIVSLLENTLIAFEKQQRKGF
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: CYSA_BACC1
Sequence: MSIQIQGVSKQYGTFQALTDIHLDIPKGELVALLGPSGSGKTTLLRIIAGLEEADEGSISFEGEDLTDIHVKNRQVGFVFQHYALFKHMNVFENVAFGLKVRKKSLRPSAEAIEEKVTELLKLVKMDGFAKRYPAQLSGGQRQRIALARALAVEPKILLLDEPFGALDAKVRKELRRWLRKLHDEFQITSVFVTHDQEEALDVADRIVVMNEGRIEQMGTPEEVYENPASPFVYDFLGNVNLFHGRVHKGKLNVGSVELEAPEHKHISNVDGVAYVRPHHLSISRTKQSVDAIPAKVSYSHAVGPVVYVELKRDGTDEYLEAEISKEQFRQLSIQAGDVVYVQPKEVKVFIPEDFVI
What is the function of this protein?
Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein CysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RRP41_METMA
Sequence: MSNKPENLTLITDDGLRLDGRRADEIRPMKIEVGVLSRADGSCYLEWGRNKILVGVFGPREAHPRRSQRADSAVIRYRYNMASFSVEDRARPGPSRRSIEISKVSREAFEPVIMAELFPKTAIDIFVEVLQADAGTRTAAINASSIALADAGIPMKGLITSCAFGKVDGKIVLDLNKEEDNYGEADFPVAMTQDGEITLIQMDGNLTPDEIKQGLELVKKGCKEILEIQQAVLRKKFETPVEEVSEETAPEKGAEKEVLEPSPVAAIVEETPEEAEEPEVEISEEVEAEILASEVIPDFEDELEEEIEEELEESEEDLETEEEEFEEEALEEEAEPEEDLEEDLEEDLGEELEEEEEELEEEEFEEEALEEETELEASLECAPELKEFDEIEARLEKEDASIEAEEEIEPEAEEATEEGLEEEAEIEETAASEEENIEAEAEAEEEAEPEVEAEEISTEAEEAEEEPEEEKSEGPWKVVKDPSEAGTRGEKDE
What is the function of this protein?
Catalytic component of the exosome, which is a complex involved in RNA degradation.  Has 3'->5' exoribonuclease activity.  Can also synthesize heteromeric RNA-tails.
What are the official names of this protein?
Exosome complex component Rrp41.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family. Rrp41 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTG1B_HUMAN
Sequence: MQAEGRGTGGSTGDADGPGGPGIPDGPGGNAGGPGEAGATGGRGPRGAGAARASGPGGGAPRGPHGGAASGLNGCCRCGARGPESRLLEFYLAMPFATPMEAELARRSLAQDAPPLPVPGVLLKEFTVSGNILTIRLTAADHRQLQLSISSCLQQLSLLMWITQCFLPVFLAQPPSGQRR
What are the official names of this protein?
Cancer/testis antigen 1, Autoimmunogenic cancer/testis antigen NY-ESO-1, Cancer/testis antigen 6.1, CT6.1, L antigen family member 2, LAGE-2.
What is the protein family that this protein belongs to?
Belongs to the CTAG/PCC1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCDGH_PANTR
Sequence: MGRGTGELGRAERLPVLFLFLLSLFCPALCEQIRYRIPEEMPKGSVVGNLATDLGFSVQELPTRKLRVSSEKPYFTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSFSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGNPPLSGTTELRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSPEVTFHSLLEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKIISSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLHASEPGLFSLGLRTGEVRTARALGDRDAARQRLLVAVRDGGQPPLSATATLHLVFADSLQEVLPDITDRPVPSDPQAELQFYLVVALALISVLFLLAVILAIALRLRRSSSPAAWSCFQPGLCVKSGPVVPPNYSEGTLPYSYNLCVAHTGKTEFNFLKCSEQLSSEQDILCGDSSGALFPLCNSSESTSHPELQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin gamma-B5, PCDH-gamma-B5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: UBP16_YEAST
Sequence: MSWIKNVTESPTSLIKKVSCGLIIAASLYAIAPSLSALVFGDSKQSIGKYTTVGLINRGNDCFITSSLQGLAGIPRFVEYLKRIRTVLLELETKLSNNAKGDNPTVDNTTRHSRLENSSNSLAPLHESLTSLILDLISVKDRKTSISPKIVINTLESIFKSKISSKQNDAHEFTLILLQTLQEERSKLIDYSKQICNLNIPKFPFEGETSKFLVCLKCKGLSEPSYKQTFIRELSVPQQTSENLSNILAHDETEIIDDYSCLICQIRAILNHEEYRNFKDCTPDEILMLDRLKNYATKAPINENLPFEVEQYVKRYSKGNLQVSNIKGKVIKKDVVVQLPDILIVHLSRSTFNGITYSRNPCNVKFGERITLSEYTLAESGTITENRQVKYNLKSVVKHTGSHSSGHYMCYRRKTEIRFGKEDESSFRRAPVVNNEVNKNREQNVAHNDYKKSRYKKVKNALRYPYWQISDTAIKESTASTVLNEQKYAYMLYYERVNK
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 16, Deubiquitinating enzyme 16, Ubiquitin thioesterase 16, Ubiquitin-specific-processing protease 16.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: CSN4_BRAOL
Sequence: KRKFLDAALRYYSISQIEKKAYLPDKSTVLDRAMIEHNNLLSASK
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF.  It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes (By similarity).
What are the official names of this protein?
COP9 signalosome complex subunit 4, Signalosome subunit 4, Constitutive photomorphogenesis protein 8, FUSCA protein 4, FUSCA4.
What is the protein family that this protein belongs to?
Belongs to the CSN4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CYSG1_HALHL
Sequence: MHHYPIFLKLHGCRCLVVGGGEAAARRAGDLLRAGARVELIAPVLAAPCEQLLDTSPGELHHRAEPFAAGMEEGAALVVGASGDEATDRTVYEACRARGIPVNVAGRPSLSTYITPVQVDRSPLQLAVSSGGAAPVLARQIASRLETLLPAAYGRLARLAGRMREQVRVALPDKDWRLRFWEQIFDGAAAESVLAGREAEGEAELLRLLEQEQARPAPQGEVFLVGAGPGDPDLLTFRALRLMQRADVVLYDRLAAPALLDLVRKEAERIPVGKRRGRHTLPQERINERLVELARAGKRVLRLKGGDPFLFGRGGEEIEGLIEQDIPFQVVPGISAAQGAASYAGIPLTHRDYAQTCRLLTGHRRAGHPQMKAHAPYRQDETLIIYMGLVNLEAVCEQLCECGLPPEHPAAVVAQATTPQQRVVLGNLRTLAERVRAERVESPALVVVGPTVQLHPRLGWYRGEAEDRDAAASIDPCWTGGMRD
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase 1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: LCN10_MOUSE
Sequence: MKLEMALSIALALAVVSWTQEFFPKEAQTLNWSKFSGFWYIIAIATDTQGFLPARDKRKLGASVVKVHKTGQLRVVIAFSRPRGCQSREVTLKKDRKRPVFRNTLKGVKGFHVLSTDYTYGLVYLRLGRGGSNYKSLLLFNRQNISSFLSLREFLDTCHILQLTKQATILPKDDSCAHTILP
What is the function of this protein?
May play a role in male fertility.  May act as a retinoid carrier protein within the epididymis.
What are the official names of this protein?
Epididymal-specific lipocalin-10.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.