PharMolix/UniProtQA huggingface dataset:
Protein: SYY_RICRS
Sequence: MRFIEEFINKGYFHQCTDLDRLTAITKETKIAAYIGFDCTATSLHIGSLMQIMILRLLQQHGHKPIVIIGGGTSKIGDPTWKDEVRKILSKEDIAKNAEGIKKSLSKFIKFGDGKSDAIMLDNAEWLDSFNYLDFLRDFGSYFSVNRMLTMDSVKLRLEREQHLSFLEFNYMLLQAYDFYYLSKHYNCSLQLGGSDQWGNIVMGADLIRKISGKEVFGMTTPLLTTSSGAKMGKTAAGAVWLNEDLLSPYDYYQYWRNCEDADIVRFAKLYSEFTQEELNRFESLAAEDINAAKKQLAYELTKLCHSEQAAKSALETAVKIFEEGQIDENLPTVVLEQEVLQAGISAYELFYEAGLATSKSEARKLIRGNGAKINDRLVADENMIINTNFLLDKKVIKLSAGKKRHILVRV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURE_STRP8
Sequence: MITIEQLLDILKKDHNFREVLDADGYHYHYQGLSFERLSYDSRQVDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMAFYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLTTPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVVINSGMDHFSFLADQVADQEHVFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAVIIAGKGADAYQIVKGQQVAYAGDLAIAKHYL
What is the function of this protein?
Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase, L-lysine-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:L-Lys ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_CUPTR
Sequence: MTFEPSATLRDPFVLYGESFGSRLLLGTARYPSPATLEAAVQASAPAMITVALRRQGAVGDGEGGQAFWQMLKALNVPVLPNTAGCFTAQEVITTAMMAREVFETPWIKLELIGDDYTLQPDTLNLPAVAETLLKEGFKVLPYCTEDLVLCRRLLDVGCQALMPWAAPIGTGRGAVNPHAMRVLRERLPDTPLIVDAGLGLPSHAAQVLEWGYDGVLLNTAVAQAAYPVDMARAFAQAVAAGRTAYLAGPMPEREVAQASTPVVGMPFWHADNTEQRA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_XYLFT
Sequence: MPSSYDRVSKNYRQSELDKFASFTSGWWDPHGPQKPLHALNPVRLDYISKRVSLSGARVLDVGCGGGLLSEALARQGAHVTAIDLVPELIKVARLHGLESGIQVDYRIQAIEDLLAEQPAPFDAIACMEMLEHVPDPAAIVDACAHLLKPGGRLFVSTINRTLAAFMLAVVGAEYVVRLLPKGTHQYKDFIRPAELAAWLRHAGLHLEDVSGMRYEPWRNRARLTARTDINYLACAISPEASHATE
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: AGAP3_MOUSE
Sequence: MNFQAGGGQSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGPSQQLAGGPPQQFALSNSAAIRAEIQRFESVHPNIYAIYDLIERIEDLALQNQIREHVISIEDSFVNSQEWTLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLCSFRNASEVPMVLVGTQDAISAANPRVIDDSRARKLSTDLKRCTYYETCATYGLNVERVFQDVAQKVVALRKKQQLAIGPCKSLPNSPSHSAVSAASIPAVHINQATNGGSSAFSDYSSSVPSTPSISQRELRIETIAASSTPTPIRKQSKRRSNIFTSRKGADLDREKKAAECRVDSIGSGRAIPIKQGILLKRSGKSLNKEWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRLPRATPTTAPGTSPRANGLAMERSNTQLGGATGAPHSASSTSLHSERPHSSAWAGSRPGPEGLHQRSCSVSSTDQWSEAAALPASMQHPASGPAESLSSSPKLEPPPSPHSNRKKHRGKKSTGTPRPDGPSSAAEEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQNTALAVQAVRTVRGNSLCIDCEAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALDGYSKPGPEACREEKERWIRAKYEQKLFLAPLPSSDVPLGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQLLIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGEGCGLAPTPNREPANGTNPSAELHRSPSIL
What is the function of this protein?
GTPase-activating protein for the ADP ribosylation factor family (Potential).  GTPase which may be involved in the degradation of expanded polyglutamine proteins through the ubiquitin-proteasome pathway.
What are the official names of this protein?
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3, AGAP-3, CRAM-associated GTPase, CRAG, Centaurin-gamma-3, Cnt-g3, MR1-interacting protein, MRIP-1.
What is the protein family that this protein belongs to?
Belongs to the centaurin gamma-like family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Upon oxidative stress, translocates to PML nuclear bodies.
Protein: NU4M_TROWA
Sequence: PIAGSMVLAAILLKLGGYGIIRMMQILPTTKTDVFLPFIVLALWGAILANLTCLQQTDLKSLIAYSSVSHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRVLILTRGFHNILPMATTWWLLINLMNIATPPTINFTSELLIISALFNWCPTTMIMLGLSMLITASYSLHMFLSTQMGPTMLSSQTEPTHSREHLLMILHIIPLVLISMKPELVI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MURQ_ECOSM
Sequence: MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYAHQLGCRTVGISCNPGSAVSTTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVNIVKNATGCSAEQAETALIACKRNCKTAIVMVLKNLDADEAKKCLDQHGGFIRKALEKE
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.  Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: MTND_XANOP
Sequence: MSRLRIFADTNPATPEFDSRDGDAIASELKKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDSTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYAPEKPHKAS
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: LEU3_METTH
Sequence: MKSMKIAVIPGDGIGVEVMEAALHILNTLDLDLEFIHADAGDACLKRTGTALPEETLEAVGEARATLFGAAGESAADVIVRLRREFDLFANLRPVKSLPGVPCLYPDLDFVIVRENTEDLYVGDEEYTPEGAVAKRIITRTASRRISQFAFQYAQKEGMQKVTAVHKANVLKKTDGIFRDEFYKVASEYPQMEATDYYVDATAMYLITQPQEFQTIVTTNLFGDILSDEAAGLIGGLGLAPSANIGEKNALFEPVHGSAPQIAGKNIANPTAMILTTTLMLKHLNKKQEAQKIEKALQKTLAEGLVTPDLGGKLGTMEMAAEIARHLED
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, IMDH, Beta-IPM dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL620_MIMIV
Sequence: MLEKYISIKMRVNPVNNTINNTDDIKSTSLFPKKKNVFFIEGGGTKGVYAMGVLNYLYDENVYIKLQDVDIFGGTSVGSILAVGLSLGYQKKDFEKFVETFDLSKFVDSKYYAPFTLYRFLTKGHLYDDTNRQTLVKKILNINIETIRSHLDLPIDSDFEGTDITFWHLKKLIKKYPQIYKHLLINSVDISREQQIFMTTLDDNWDNIKLYDSILASSAFPFVFPSSKFYYNSTTQKYQYESLTDTNDKITENSFIDGGVANNIPLDYLILNSERFTDCNLWSLQFTTTPAYSKITGPIALIQKLINFAFSYGRKSFGLELIHEKYQVNVINLNLSANTFDTYNNNQIKEITRQIYDQCLSGQLHFDNVDSQ
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Uncharacterized protein L620.
Protein: RL31_THEVB
Sequence: MPKPNIHPQWYPEAKVYCDGEVIMTVGSTKPELHVDIWSGNHPFFTGTQKIVDAEGRVERFRRKYSGTKPQQTAKGKKAAPKSTPKTNKKG
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: RPOC1_CUSEX
Sequence: MNNNFSSMIDRYKHQQLQIGSVSPQQISAWATKILPNGEIVGEVKKPYTFLYKTNKPEKEGLFCERIFGPIKSGICACGNYRVIGDEKEEQKFCEQCGVEFVDSRIRRYRMGCIKLACPVTHVWYLKRLPSYIANILDKPLKELEGLVYCDFSFARPITNKPTFLRLRGLLKYEIQSWKSSIPLFFTTQGFDTFRNREISTGAGAIREQLADLDLRILLENSLLEWKDLGEEENTGNEWEDRKAGRRKGFLVRRMELVKHFIRTNIEPKWMVLCLLPVLPPELRPIIQIDGGKLMSSDINELYRRVIYRNNTLTDLLTTSRSTPGELVMCQEKLVQEAVDTLLDNGIRGQPMRDGHNKVYKSFSDIIEGKEGRFRETLLGKRVDYSGRSVIVVGPSLSLHQCGLPREIAIELFQPFVIRDLIKQHLASNIGVAKSKIREKEPIIWEILQDVMQGHPVLLNRAPTLHRLGIQAFQPVLVEGRVICLHPLVCKGFNADFDGDQMAVHVPLSLEAQAEARLLMFSHMNLLSPAIGDPISVPTQDMLIGLYVLTSEKHRGICTNRYTNCNIRTLQTKSSDYSNSKYKNPYNNGPFFCNSYDAIGAYRQKRINLESPLWLRWRLDRRVITSRETPIEVHYESRGTYFEIYGHFLIVRSLKKKILFIYLRTTVGHISLYREIEEAIQGFSRAWSSDT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', PEP, Plastid-encoded RNA polymerase subunit beta', RNA polymerase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC1 subfamily.
What are the subcellular locations of this protein?
Plastid.
Protein: PHNS_MEGGA
Sequence: MKFCTAVAVAMGMGPAFAPKVAEALTAKKRPSVVYLHNAECTGCSESLLRTVDPYVDELILDVISMDYHETLMAGAGHAVEEALHEAIKGDFVCVIEGGIPMGDGGYWGKVGRRNMYDICAEVAPKAKAVIAIGTCATYGGVQAAKPNPTGTVGVNEALGKLGVKAINIAGCPPNPMNFVGTVVHLLTKGMPELDKQGRPVMFFGETVHDNCPRLKHFEAGEFATSFGSPEAKKGYCLYELGCKGPDTYNNCPKQLFNQVNWPVQAGHPCIACSEPNFWDLYSPFYSA
What are the official names of this protein?
Periplasmic [NiFe] hydrogenase small subunit, NiFe hydrogenlyase small chain.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KTHY_BACCQ
Sequence: MKGLFVTIEGPEGSGKTTLIQGLLPYFEQKEQKVMATREPGGIAISEEIRTILHKQEYTMMEARTEALLYAAARRQHLVEKVMPALNKDYLVLCDRFIDSSLAYQGYARGLGMDKVFEINRFATEDCMPSLTIYLDIEPEVGLARIAKDAGREVNRLDMEDISFHKRVREGYLQVVERFSDRIVLVNADQPMEKLIEEVIQVIEDKLL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NUOH_BAUCH
Sequence: MLHLRYEYLLAIVKAIVTLLSVVTIGAYMSFFERRLLGLFQHRYGPNRVGWGGSLQLLADTIKILFKEDWIPPFADRIIFTLAPIIAFTSLLLVFAIMPISPNWVVIELNIGILFFLMMAGISVYAILLGGWSSNNKYSLLGAMRAAAQTLSYEVFLGLSIMGVVAQAGSFNISTIVADQTHIWNIVPQFFGFITFYLAGLAICHRHPFDQPESEQELADGYHIEYSGMKFGLFFIGEYISLVTISALTITLFFGGWQGPWLPPYIWFIIKTTVFIIIFILIRAALPRPRYDQVMILGWTICLPLTLMNLLVTAIVILYNT
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SUCC_HAEI8
Sequence: MNLHEYQAKQLFEHYGLPVKNGAVCQSVEDVDLVLAQLSGDKWAAKCQVHAGGRGKAGGVKLVQDVEEARAFAEKWLGQRLVTFQTDKLGQPVNQIYFEETCDIDKEFYLSAVVDRASQKVMFIASPAGGMNIEEVAQNSLHLLHKVEIDPLFGGLPYQGRELAFKLGLSGTQNKQFTDIFMGLSRLFLEKDLSLVEVNPLVLTKQGYLVCLDAKISVDDNALFRHKDLLALQDLTQNDAREAEAEKFQLNYVALEGDIGCMVNGAGLAMGTMDIVKLYGGKPANFLDVGGGATKERVAEAFKIILTDPSVKVILVNIFGGIVRCDLIAEGVIAAVNEVGVRVPVVVRLEGTNAEMGRQILAQSDVNILTAQSLQQAAELAVNAAKGEH
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PROA_TOLAT
Sequence: MSLLAMGKAAREASFELAVAATARKNQALLAMAEELELQQDVILAANAKDIEAGRSSGLTDAMLDRLLLNESRLAGIVADVRKVVTLDDPVGSEIDSRVLENGMRLSRRRVPIGVIGVIYEARPNVTIDIAALCLKTGNASILRGGRETFNSNMALVKVIQAALAKTGLPAASVQYIESPDRALVSELLTMDQYVDMIIPRGGANLHRLCKDQSTIPVIIGGFGVSHLYVDESADLIRAIDVIDNAKVQRPSACNSLDTLLLNEKIAAEIVPALVARMNQQKVTLVAEPKAFALLQAAGAEQLRAAGAEDFDTEWLSLTLGVKVVADVKAAIAHLQEHNACHSDAILTNDLKCAEYFINAAGSAAVYVNASTRFTDGAQFGLGAEVAVSTQKLHARGPMGLTELTSYKWIGQADYLSRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMJ_HELPJ
Sequence: MEFLSGYFLWVKAFHVIAVISWMAALFYLPRLFVYHAENAHKKEFVGVVQIQEKKLYSFIASPAMGFTLITGILMLLIAPEMFKSGGWLHAKLALVVLLLIYHFYCKKCMRELEKDPTGKNARFYRVFNEIPTILMILIVILVVVKPF
What is the function of this protein?
Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.  Is involved in the biosynthesis of tetrapyrrole molecules like heme.  Does not use oxygen or artificial electron acceptors such as menadione or benzoquinone.
What are the official names of this protein?
Protoporphyrinogen IX oxidase, PPO.
What is the protein family that this protein belongs to?
Belongs to the HemJ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VAC14_YEAST
Sequence: MEKSIAKGLSDKLYEKRKAAALELEKLVKQCVLEGDYDRIDKIIDELCRDYAYALHQPMARNAGLMGLAATAIALGINDVGRYLRNILPPVLACFGDQNDQVRFYACESLYNIAKIAKGEILVYFNEIFDVLCKISADTENSVRGAAELLDRLIKDIVAERASNYISIVNNGSHGLLPAIKTDPISGDVYQEEYEQDNQLAFSLPKFIPLLTERIYAINPDTRVFLVDWLKVLLNTPGLELISYLPSFLGGLFTFLGDSHKDVRTVTHTLMDSLLHEVDRISKLQTEIKMKRLERLKMLEDKYNNSSTPTKKADGALIAEKKKTLMTALGGLSKPLSMETDDTKLSNTNETDDERHLTSQEQLLDSEATSQEPLRDGEEYIPGQDINLNFPEVITVLVNNLASSEAEIQLIALHWIQVILSISPNVFIPFLSKILSVLLKLLSDSDPHITEIAQLVNGQLLSLCSSYVGKETDGKIAYGPIVNSLTLQFFDSRIDAKIACLDWLILIYHKAPNQILKHNDSMFLTLLKSLSNRDSVLIEKALSLLQSLCSDSNDNYLRQFLQDLLTLFKRDTKLVKTRANFIMRQISSRLSPERVYKVISSILDNYNDTTFVKMMIQILSTNLITSPEMSSLRNKLRTCEDGMFFNSLFKSWCPNPVSVISLCFVAENYELAYTVLQTYANYELKLNDLVQLDILIQLFESPVFTRMRLQLLEQQKHPFLHKCLFGILMIIPQSKAFETLNRRLNSLNIWTSQSYVMNNYIRQRENSNFCDSNSDISQRSVSQSKLHFQELINHFKAVSEEDEYSSDMIRLDHGANNKSLLLGSFLDGIDEDKQEIVTPISPMNEAINEEMESPNDNSSVILKDSGSLPFNRNVSDKLKK
What is the function of this protein?
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).  Regulates the synthesis of PtdIns(3,5)P2 by positive activation of FAB1 and by controlling FIG4 localization.  Required for FIG4-mediated turnover of PtdIns(3,5)P2 after hyperosmotic shock.  Essential for the control of trafficking of some proteins to the vacuole lumen via the multivesicular body (MVB), and for maintenance of vacuole size and acidity.
What are the official names of this protein?
Vacuole morphology and inheritance protein 14, Swollen vacuole phenotype 2 protein.
What is the protein family that this protein belongs to?
Belongs to the VAC14 family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Note=Limiting membrane of the vacuole. Localization requires FAB1 and FIG4.
Protein: SPIKE_BAVJK
Sequence: MLSETELRALKKLSTTTTRVVGDSTLALPSNVKLSKGEVEKIAVTKKEMFDELAQCNLPTIELITREHTFNGDAIRFAAWLFLMNGQKLMTANNVVVRMGMQYSTNLAGNNVEINYVTSNSVVKLGHIPAGVLAAPYSGKGSGLFITYEQNLITNTVETGKVCVLFITSLSTTASAVNSFAYSYCNVPVESWDFNMIKLTAETSCASLTAMTNLVNTLVPDDRVRPVGLYVDIPGVTVTTSASLGSLPITTIPATTPLIFSAYTKQVEEVGVVNTLYALSYLP
What is the function of this protein?
Spike-forming protein that mediates virion attachment to the host cell receptors and plays a major role in cell penetration.
What are the official names of this protein?
Spike protein VP9, Virion protein 9, VP9.
What are the subcellular locations of this protein?
Virion.
Protein: SPRT_PECAS
Sequence: MNTPRIPIASHQAVMRCLRDKLQQANLTLQTDYTEPAVSYQQRGATAGTAWLQHWEIRLNPVLLQENQQTFIDEVVPHELAHLLVYARFGRVAPHGKEWRWMMENVLHVPAKRTHRFAVQSVQGKTFTYLCDCQRHELTIRRHNRVLRGETEYRCRRCGKTLRHDVKSSI
What are the official names of this protein?
Protein SprT.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_NOCFA
Sequence: MLRIGLTGGMGAGKSTVARILADLGAVIVDSDVIAREVVAPGTEGLAALVAAFGSDILAADGSLDRPALAAKAFADDAARAKLNSITHPLVGKRTAELIGAAPAEAIVVQDIPLLVENGLAPLMNLVLVVDVPAETRIRRLVEFRGVAEADARARIAAQATDEQRRAVADVLLDNSGPEGAVEQVVRELWERRLVPFERNLRAATPAAPGTSELRVDAERQAQAQRLVARLAVAGGAAAARIEHVGPTAVPDLPARDLLELQIVVADAAAATGLRDALGAAGFPAMSGEGSGALRAAAWHGSADPGRPAVVAVRVEGTPEQRFASALGERLRGDAALREEYLDVARKAEAEAAGSVGAAAGAAFDAVLHPWLAEVAERLLGTV
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the UPF0157 (GrpB) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_PELUB
Sequence: MSEVKSDIQIAREAKMQPINDILAKINVPDESSAFSPMGRHIAKINLEYLDTLKDKPNGKLVLVTAITPTPAGEGKTTTSVGLNDGLNKIGKKSIVCLREPSLGPSFGMKGGAAGGGYAQVVPMEQINLHFTGDFHAITSAHNLLSALIDNHIYWGNKLDIDVRRIVWKRVMDMNDRSLRSININLGGVANGFPREDGFDITVASEIMAIFCLSNDLEDLEKRIGNITIAYTRDKKPVYAKDLKAQGPMTVLLKDAIRPNVTQTLENNPAIIHGGPFANIAHGCNSVIATKTGLKLADYVVTEAGFGADLGAEKFLDIKCRKSDLKPSCVVIVATIRALKMHGGVAKDDLKTENVEALKKGLVNLQRHVENVKKFGLPVAVAVNHFIKDTENEVKALIEFCDTIGVKASLCTHWANGGEGTKELASHVAELCEKNEDKFKFLYESKTPLFKKIETIAKEIYRADEVIADTKIRDQLKSFEDAGYGDFPICIAKTQYSFSTDPSLKGAPTGHSLPIREIKLSSGAEFIVVICGAVMTMPGLPRVPAADSIKLNKDGEIEGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: AZOR_SHEFN
Sequence: MAKVLILKSSILGSYSQSSALVDYLNQQWSSKGAQIKVRDLGENTLPMLDGELASGLRGGDNLSERQLSALALSDELVAEIKAHDTIIIAAPMYNFGIPTTLKNWIDLIARAGVTFTYTDTGAVGLIEGKRAIIVTTRGGAHKGGPTDHVVPYLTTVLGFIGINNVETIYAEALNMGPDAAETGISQAKLAIDAITL
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: NCPP_ARCFU
Sequence: MGSKNPTKIEGARRAFEQYFDDVEIVGVEVSTSAPPQPFDAETVRGAIERAKKAYSPDFDFSVGIEAGLFRSECTITGYLDFQVAAVYDGERCTIGFGPGFEYPKLVVEEVLKGKEVGEVMEKVSGIKNLGKKVGAVHYLSKGAISRTDLSRISVTMALIPFINREMYL
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Probable inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: TSSK1_MOUSE
Sequence: MDDAAVLKRRGYIMGINLGEGSYAKVKSAYSERLKFNVAVKIIDRKKAPSDFLEKFLPREIEILAMLNHRSIVKTYEIFETSDGKVYIVMELGVQGDLLEFIKTRGALQEDDARKKFHQLSSAIKYCHDLDVVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDDSGRLILSKTFCGSAAYAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKHLTGECKDLIYRMLQPDVNRRLHIDEILNHCWVQPKARGLSSGAINKEGESSRATEPSWIPEPGADKKSATKLEPREEARSEARSESKPQEDTLQVVRQSENVGLSSELNRDTEEGHPQQPSETHT
What is the function of this protein?
Testis-specific serine/threonine-protein kinase required during spermatid development (PubMed:20053632, PubMed:23599433).  Phosphorylates 'Ser-281' of TSKS (PubMed:20053632).  Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm (PubMed:20053632).  During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body (PubMed:20053632).
What are the official names of this protein?
Testis-specific serine/threonine-protein kinase 1, TSK-1, TSK1, TSSK-1, Testis-specific kinase 1, Serine/threonine-protein kinase 22A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome. Cell projection, cilium, flagellum. Note=In spermatozoa, present in the sperm head and in the flagellum.