PharMolix/UniProtQA huggingface dataset:
Protein: SCIN_STAAN
Sequence: MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGLKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
What is the function of this protein?
Involved in countering the first line of host defense mechanisms.  Efficiently inhibits opsonization, phagocytosis and killing of S. aureus by human neutrophils.  Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inactivation.  The convertases are no longer able to cleave complement C3, therefore preventing further C3b deposition on the bacterial surface and phagocytosis of the bacterium.  Also prevents C5a-induced neutrophil responses (By similarity).
What are the official names of this protein?
Staphylococcal complement inhibitor, SCIN.
What is the protein family that this protein belongs to?
Belongs to the SCIN family.
What are the subcellular locations of this protein?
Secreted.
Protein: LGT_SINMW
Sequence: METIATRLAILPFPEIDPVIFTIGPLAVRWYGLAYVVGILLGWFYARRIVQNAALWRNGTPACNLTQLDDFLLWAAGGIVLGGRIGYILFYDLGSILDDPLRAIQIWNGGMSFHGGLVGTTLAMIIFARRNAIPIWSLFDVVAAVVPIGLFFGRIANFINGELWGRLSSVPWAVVFPTGGPFARHPSQLYEAALEGLVLLAVLAWFVYRRKALKIPGLVTGIFVCGYAASRIFVEFFREPDAQIGYLAGDWLTMGMVLSVPMALIGIWAIARARSAAAAA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BRME1_MOUSE
Sequence: MNKKKQRNSGVGLHPSKPSKNPRLRDSQSSMMVHSHYSRESEDSSEPAPSVELGGEEPLHEAFSCPVEDTGAASDLAGSPKELVPLPPSQNSVGKFVPQFAKPRKTVTRKAKAWEEDLEGCTTSQETRPELGALKAASQPQRESLRFPPHDIRPEVQTQPDGTLSKERTISLDNRSLGNNGFEMATVQDSSSPLSDAAAEGREADSRDPQERDAQGGEAGAQHSGEPQEGEDILYTSALAPASEPTWSVAQDLSVPTYTLSSTAAAPSSTSPADASLMDTVITEVSLDPSVLQQSAPQVAKLLGSLDEQIPDGGCIGTLLSSTPLAEETTAGREEARWEERCHGDTLASFTETEPEKQEPVTEAGDSGHIAQEMDPVVKTKDSGSDEQSPGDIGMLPLPAQSMNQMLVELRGLTCDQDLEGLSTPHTSSQLEHTCAASDPPQSTKDCHSSPGIPVHLAAPCPRDQAAWQESSAMELDFLPDSQIQDALDATNMEQGFPSGSMPDLGWPVPSSQSIGGSPKAVTKPQSRSHVETWAQETYRMQDATDTVRGLVVELSGLNRLIMSTHRDLEAFKRRKTKSLPYLTKGLGSLPRGDQSWRDL
What is the function of this protein?
Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair (PubMed:32463460, PubMed:32460033).  Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with and stabilization of the BRCA2:HSF2BP complex during meiotic recombination (PubMed:32460033, PubMed:32463460).  Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility (PubMed:32463460, PubMed:32460033).
What are the official names of this protein?
Break repair meiotic recombinase recruitment factor 1.
What are the subcellular locations of this protein?
Chromosome. Note=During meiosis, recruited to chromosomes and localizes on recombination sites in a double-strand break-dependent manner. First appears on the chromosome axis at leptotene. Along with the progression of meiotic recombination, released from the axis to form bridge-like structures linking homolog axes before they are synapsed. Finally, located between synapsed homolog axes and on the synaptonemal complex (SC).
Protein: NAMA_BACMK
Sequence: MEFQLFSPYTIKDVTLKNRIIMSPMCMYSSENEDGQVTNFHLVHYGTRAAGQVGLVMIEATAVLPEGRISNKDLGIWDDNLIEGLHKTTTFIHNNGAKAAIQLAHAGRKAELETDAFAPSAIPFNDRMKIPVEMNKQQIKETVSAFQKAALRSKRAGVDVIELHGAHGYLINEFLSPLSNKRIDEYGGSPENRYRFLREIIDAVNEVWNGPLFVRISANDYHPDGLTVQDYVQYTGWMKEQGVDLIDCSSGAVVPAHIDVYPGYQVQYAKHIKEHVNIATGAVGLITTGSQAEQILNNNEADLIFIGRELLRNPYFPRIAANELGFELKEPYQYRRAPGKIKTNK
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: RHOU_HUMAN
Sequence: MPPQQGDPAFPDRCEAPPVPPRRERGGRGGRGPGEPGGRGRAGGAEGRGVKCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEFDKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVKVLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQYSDTQQQPKKSKSRTPDKMKNLSKSWWKKYCCFV
What is the function of this protein?
Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration.  Stimulates quiescent cells to reenter the cell cycle.  Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.  Plays a role in the regulation of cell morphology and cytoskeletal organization.  Required in the control of cell shape.
What are the official names of this protein?
Rho-related GTP-binding protein RhoU, CDC42-like GTPase 1, GTP-binding protein-like 1, Rho GTPase-like protein ARHU, Ryu GTPase, Wnt-1 responsive Cdc42 homolog 1, WRCH-1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor. Cell junction, focal adhesion. Cell projection, podosome. Note=Localizes to podosomes in SRC- transformed cells.
Protein: RS12_BORRA
Sequence: MPTINQLIRKPRKSQKEKTASPALQNCPQKRGICTRVMTVTPKKPNSALRKVARVRLSNGFEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGAKDTLGVNNRKQGRSKYGTKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: NAGK_ECOUT
Sequence: MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVCELVAEADRRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRLPVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQGDEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLAERLPRHLLPVARVPRIERARHGDAGGMRGAAFLHLTD
What is the function of this protein?
Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.
What are the official names of this protein?
N-acetyl-D-glucosamine kinase, GlcNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NagK subfamily.
Protein: ATPG_DESAP
Sequence: MPALRDFRRRIKSVKSTQKICKAMKAVATAKMARAQATVVAARPYARQLHEVLGRVASAARDVQNPLLTVREPKRVCYIVITADRGLCGGFNSNILRTAVKELSKWEEFKLVAVGRKCRNFFRFRDWERDAEFIGLGENIRFEQGQQIARFVINKYIAGEYDAVYMVYSKFVNMLVQQPTVVKLLPVEPPAEEAAEKAGGEEAAAPKKATVDYIFEPSAADVLDYLLPRYVENSVYHGLIESKASEQSARMMAMDAATKNAGEMIDRLTLQMNRLRQEGITKELLDIVGGAAALE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HBA_CANLA
Sequence: MVLSPADKTNIKSTWDKIGGHAGDYGGEALDRTFQSFPTTKTYFPHFDLSPGSAQVKAHGKKVADALTTAVAHLDDLPGALSALSDLHAYKLRVDPVNFKLLSHCLLVTLACHHPTEFTPAVHASLDKFFTAVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CPND_DICDI
Sequence: MNPIQPIPKSKIEIRIKCKDLTSKDLLSQSDPQAIVYLKQQQRNDWIQQGKTEKLKNQKSPEFKQSITVDYHFEEVQLLKIVVIDIDKDIKLLKDFDDHDLIGEVNVSLGSILSSPGGRMKMSLTKNGILSGSITISTEEIRETGANIYFALEGNHLDKKDLLSSDPYFKIYKSGGTLVYQSDVIKNTLNPTFPPVYLKLEELNGGDMFRELTFEFMDWDKIGDHDLIGRFTTNTDTILRGGALEFEIINPKKVGKSGYKNSGIIKFYIARIQGDPTFLDYLHGGLEINLMVAIDCTASNMPPDVSTSLHYNTPTQPSQYASSIAAVGNVLAPYDYDQMIEVVGFGGLYNGHTSHCFPFNLTNGDDNKSEAHGLQEVLDIYYNNVLKIPFSYPTNFENVIHHAIKRASKSTQSNQKYTVLLIITDGDISDTQKTIDELVSASKSALSVVIIGVGNYHFEAMKILDGDEKGLVDSKGNPSKRDICQFVPFNDFKNYPEALAHETLKEIPSQVLSFMKLSKIHPNQPRQFNC
What are the official names of this protein?
Copine-D.
What is the protein family that this protein belongs to?
Belongs to the copine family.
Protein: MP701_ORYSJ
Sequence: MADPYGDGKGLKQQQRQKLKPALEVEDFINLLHGSDPVRVELTRLENELQYKEKELGEAQAEIKALRLSERAREKAVEDLTEELTKVDGKLKLTESLLESKNLEAKKINDEKKAALAAQFAAEATLRRVHAAQKDDDMPPIEAILAPLEAELKLARHEIAKLQDDNRALDRLTKSKEAALLEAERTVQIALAKASLVDDLQNKNQELMKQIEICQEENKILDRMHRQKVAEVEKLTQTVRELEEAVLAGGAAANAVRDYQRKVQEMNEERKTLDRELARAKVSANRVAVVVANEWKDGNDKVMPVKQWLEERRILQGEMQQLRDKLAIAERAARSEAQLKDKFQLRLKVLEEGLRMSTTRTNVSAARRQSIGGADSLSKTNGFLSKRPSFQMRSSVSTTTTTLVNHAKGASKSFDGGCRSLDRYKGHVNGSGMNVSTDSSEDKESNNSDEKANEFTSVETEDTVSGLLYDTLQKEVIALRKACHEKDQSLKDKDDAVEMLAKKVDTLTKAMESEGKKRRMEVAAMEKEMAALRLEKEQDNKAKRFGSSSSQLPPGRTLPRSGSARNM
What is the function of this protein?
Plant-specific protein that interact with microtubules.
What are the official names of this protein?
Microtubule-associated protein 70-1, AtMAP70-1, 70 kDa microtubule-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the MAP70 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associated to microtubules.
Protein: RL3_BORGP
Sequence: MLGLIGKKVGMTQIFQKNGIVIPVTVIEFQPNYIIGKKTVDRDGYSALIAGSVDLKGSKVSKPIKGQYKSLKDIEPKKYVIELKGLDGYDAGDEIKVDVFKSVKYVDVTGTTKGKGFQGAMKRHNFSGGPSSHGSKFHRHLGGTGQATTPARTFKGTKMAGRMGGNKQTIQNLEVVLIDEENRAILVKGAVPGAKGSFVVVKKSKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: LBH_BOVIN
Sequence: MSVYFPIHCPDYLRSAEMTEVMMNTPSMEEIGLNPRKDGLSYQIFPDPSDFDRCCKLKDRLPSIVVEPTEGEVESGELRWPPEEFLVQEDAQDNCEETASENKEQ
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Protein LBH.
What is the protein family that this protein belongs to?
Belongs to the LBH family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LGT_BURP1
Sequence: MIIHPNFDPVAIHLGPLAVRWYGLMYLVGFILAIVVGRLRLKLPHVAAQGWSAKDIDDMMFYGVLGVVLGGRLGYVLFYKAGYYFSHPLDIFRVWEGGMSFHGGFLGVTLAMALFAWQRKRHWLEVTDFVAPMVPTGLAAGRLGNFINGELWGRVTSPDAPWAMLFPGASRDDAAWLAAHQDIAAKWNLNEVFLSHQMLPRHPSQLYEIALEGIALFFVLWFFSRKPRPMGAISALFLIGYGAARFTVEFAREPDDFLGLLTFGLSMGQWLSLPMIVAGVLMMIWAYRRGGVAKQA
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 6P21_YEAST
Sequence: MFKPVDFSETSPVPPDIDLAPTQSPHHVAPSQDSSYDLLSRSSDDKIDAEKGPHDELSKHLPLFQKRPLSDTPISSNWNSPGITEENTPSDSPENSATNLKSLHRLHINDETQLKNAKIPTNDTTDYMPPSDGANEVTRIDLKDIKSPTRHHKRRPTTIDVPGLTKSKTSPDGLISKEDSGSKLVIVMVGLPATGKSFITNKLSRFLNYSLYYCKVFNVGNTRRKFAKEHGLKDQDSKFFEPKNADSTRLRDKWAMDTLDELLDYLLEGSGSVGIFDATNTSRERRKNVLARIRKRSPHLKVLFLESVCSDHALVQKNIRLKLFGPDYKGKDPESSLKDFKSRLANYLKAYEPIEDDENLQYIKMIDVGKKVIAYNIQGFLASQTVYYLLNFNLADRQIWITRSGESEDNVSGRIGGNSHLTPRGLRFAKSLPKFIARQREIFYQNLMQQKKNNENTDGNIYNDFFVWTSMRARTIGTAQYFNEDDYPIKQMKMLDELSAGDYDGMTYPEIKNNFPEEFEKRQKDKLRYRYPGIGGESYMDVINRLRPVITELERIEDNVLIITHRVVARALLGYFMNLSMGIIANLDVPLHCVYCLEPKPYGITWSLWEYDEASDSFSKVPQTDLNTTRVKEVGLVYNERRYSVIPTAPPSARSSFASDFLSRKRSNPTSASSSQSELSEQPKNSVSAQTGSNNTTLIGSNFNIKNENGDSRIPLSAPLMATNTSNNILDGGGTSISIHRPRVVPNQNNVNPLLANNNKAASNVPNVKKSAATPRQIFEIDKVDEKLSMLKNKSFLLHGKDYPNNADNNDNEDIRAKTMNRSQSHV
What is the function of this protein?
Synthesis of fructose 2,6-bisphosphate.
What are the official names of this protein?
6-phosphofructo-2-kinase 1, 6PF-2-K 1, Phosphofructokinase 2 I.
Protein: ADEC_METS3
Sequence: MQFSAYMLDVITDSIYPARISVEGGFFKEIVPIVINDDSELDISGIILPGFIDSHIHIESTMLTPAQFAKLAVRFGTTSVVCDPHEIANVAGTDGIDFMIENSKSVPFNFYFSIPSCVPATCFETSGAILDSETIGELLKKDEAVALGEMMNFPGVINGDGEVLAKLEKAKELGKPIDGHAPLLSGKDLDKYMAEHISTDHECSNFAEAIEKKEKGMKIMVREGSSAKNMEALFDFSDRLDYWKNHESFGKMPNEVLEKRIHLPIFDFIVSDDKHTTDLIKGHLNESIKKAIDLEVSPISAIEMVTVNPSTHYNLNTGAIVKGMQADYVVVDNLNDLNILKTYVAGKCVFDGENVLFDVEETEFKNTFDVSKKESEDFEISCDEPSADVNVIRCFNGELITEAESATLETKKGFVQPDLEEDILKIAVVERYGGNSIANGFITGFNLKKGAIASSVAHDSHNIVVVGTNSEDMANAVNCLIDNEGGFAIVDGDFEDSLALPIAGLMTNEDSHEVAEKLEKLHKTAADFGCKLDSPFMTMSFMALLVIPAIKISDKGLFDCINFEFIDVIKN
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: CINA_DESAP
Sequence: MQAEIICTGSELLLGYVQNTNADYLGHELAALGIEVVLQITVGDDWKIMEQAVREALERVDLVITTGGLGPTTDDITKDVIAAVLGVPMVTDDESLAQMREYFARRGIEMPDIFIRQASFPYGSRIIPNHKGTAPGALIERDGKVIVIFPGPPRELRAMFETWVKPYLLEIPGRGEVLRTRVLKLTGIAEYAVQEILKELGDLVNPSLGYLAMPGEVHLRVNAHAVDPAEAERMVEELTEKVTGLVGEYVFAIDDEVPEKTVGDLLLRKGLTVSVAESCTAGMVAARFTDVPGSSRYFIGGVVAYDNDLKREVLGVPAEILDRYGAVSEQTAVAMAEGIRRLTGSDLGLAITGIAGPDGGTRAKPVGLVYVALASARETLCQRLLLPGVRKAVRIGTVNSSLRIVKSFLNRQA
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: RPOC_CARRP
Sequence: MIKSIFKKVSIKMASSSKILSWSFGEVTHSNFINFKNLKPEPNGLFCLKIFSDFELCCLKKKCFCHNDKFLNLKKAHTGYKVGHIKLFYPAVHIWYIKSSHSNISNILNLSYKILEKIINFKLKVVIKSYDIKIKKFNLFIFDKKIKNIIFTLSGAKALKKLLSDRELFIDCLILKIKIKKCNSFSKLFSILKHINKILIFYYSGNKPSWMVLKKIPVLPPRMRPLIALSEKKFASSDINELYKIVLERNYKLKKMTTYLDPKQLLINERISLQESIYALFDNEKLINPILTSSKRVLKSFSSLIKGKYGRFRQNLLGKRVDFSGRTVITVEPNLFLYECKIPIYIALELFKPILYYELKKKKIITTISFIDDYYKKNKKQIILLLKNKVKSYFIMLNRAPTLHRMNFQSFKILLTEDKTIKIHPLVCLCYNADFDGDQMAIHLPLTNNAKVESNYLLLSINNIISPSNGNAIIIPTQDIIMGIYYFTFDFKNKSISLNDINDIINFFEFNNYNFQINIKFNNKKKINTTLGRIIINYLFFKNFDYFLNIVFKKKILTYLIKYLFDFNQLSKIIIILEKLKKIGFLISTYSGITISYFDLIEVKNTFLINKVVFKLKYNNNIFSIVELLNNFFVKIIIKKIQINKTGLKKTNNLFIMLDSGSRGSMLQIKQLIAFRGFFSKSNGDIIKDPIFDNLKNGLNMKNYFISTFGARKGLTDTSLKTANSGYLTRKLIDVSHDLVIYKIDCKTKTGIKIFLNSYFTLVELYKNLYGRLLLFSVSLKNKILLKENTLIDNKVLFLLIKKKINTIFVRSVLFCISNRGVCCFCYGIDLSTNKIVLIGVSVGIISAQSIGEPGTQLTMRTFHTGGVASYFFYSDNLIISNSGFVKFKKCKCVINKFGEVIIVSLYGEFMIFNKIILEKYKFYYGTKIKFRNGFLIKKNTKLINFNDNNFYIYSENIGYVYFKKENNIVKNYCLEDNKFYYKTLKNFKITIINKSIKKNYFIPKNFNIVVYCYDYIFPGEIIAKLVSVTILKSSIIGGLPRLSELFEARIPKLKALLSEIDGVCKIKFSHLNYIITIISKFGFYKEYTLSCLRKLYINNGDYVKIGDILSDGKPDLNEIINLISINYLLSYFVNEINSIYFPQNIYVNCKHIELILKQMTKKVKIIFSGESSCQQGDILFLEDAINENFSTLVNSRRLSYYKRIVTGITKTSLESLSFFSAASFQETNKILVNSAIKNRTDYLLGLKENVLVGRLIPAGTGLIKYFKKKSKSSKNNLDFKNRKKKFYINYF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RUVA_SALPC
Sequence: MIGRLRGIILEKQPPIVLLETGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREELGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAVDLVLTSPASPTSEDAEQEAVAALVALGYKPQEASRMVNKIARPDASSETLIRDALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: PYRB_CAMLR
Sequence: MRHLITTKDFSNGEILALFKEAKEFLDEKPRTFLEGKSVTTIFFENSTRTQSSFETAARRLGAKVLKLDVSRSSSSKGETLFDTAANLDAMAPSAIVVRHKNSGVPHTLANYTHCPIVNGGDGKHAHPTQALLDLFTIMEHFDYNVKGKKIAIVGDIKNSRVAASNLELLPRFGIDITLVAPPHFMPNYPIKKTNKLKEVIDDVDIIMSLRTQTERHNIPTYASLKDYANDFCISKDLIKDKNLIILHPGPVHRNIDISDDVMADKRCKVLTQVKNGVAIRMAVLKKLILES
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: REX_BACC1
Sequence: MEQQKIPQATAKRLPLYYRFIQNLSLSGKQRVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVNYLLSFFRETLDQDDITRVALIGVGNLGTAFLHYNFTKNNNTKIEMAFDVSEEKVGTEIGGIPVYHLDELEERLSTDIQVAILTVPATVAQSVADRLAETNVHGILNFTPARLNVSENIRIHHIDLAVELQTLVYFLKNYPQ
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1471_METJA
Sequence: MINSVDLAIGTAILLIGMAYWTVSIVEHNNNYVDIVKSDYIFDKGISTMEHLSEDGTLQDAVLLYYFDRVNDSKKLLEERIPLKHYLLYIDNNLLINKSNGVNNSNSVYILTVLTLNRSEGWYVIYGNEDFVNISKERFLDYDDAYNYLKYRNYDIHMPVYLSKNVSSSRVELYILGN
What are the official names of this protein?
Uncharacterized protein MJ1471.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ARL5C_HUMAN
Sequence: MGQLIAKLMSIFGNQEHTVIIVGLDNEGKTTILYRFLTNEVVHMCPTIGSNVEEIILPKTHFFMWDIVRPEALSFIWNTYYSNTEFIILVIDSTDRDRLLTTREELYKMLAHEALQDASVLIFANKQDVKDSMRMVEISHFLTLSTIKDHSWHIQGCCALTREGLPARLQWMESQAAAN
What is the function of this protein?
Binds and exchanges GTP and GDP.
What are the official names of this protein?
Putative ADP-ribosylation factor-like protein 5C, ADP-ribosylation factor-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
Protein: RUVA_ECOSM
Sequence: MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAEQEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: CM312_CONRE
Sequence: DQPVERHAGNKRHLNPTIRRAMIIDANRREKCCEVGWCDSGCECC
What are the official names of this protein?
Conotoxin reg3.12, Rg3.12.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RIHA_SHESR
Sequence: MSRPIILDCDPGHDDAIALILALAHPELNPLAVTTSAGNQTPDKTLKNALRILTLLNRSDIPVAGGAVKPLSRELMIADNVHGETGLDGPALPAPSFQPQAVNAVELMAEKIRQSDKPVTLVPTGPLTNIALLLASHGELHAKIERIVLMGGAAGVGNWTPAAEFNIFVDPEAADIVFKSGIPITMCGLDVTHQAQIMDEDIERIRAIPNPVAKCVAELLDFFMIYHRAPKWGFVGAPLHDPCTIAWLLNPALFDAQDCWVGIETQSELTLGMTVVDRYQLTGKPTNATVLFGIDRQGFVDLLVDSLAVYTPTYLNRR
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: MFNA_METLZ
Sequence: MEEKGCKREEVISLLSAYRAEDLHHDHILSSMCTIPHEMAVFVHGMFSATNLGDPGLFPGTTKIEDRLVHSLGELMHHPGAGGYATSGGTESNLQAIRIAKKLKPEIKNPNIVVPASAHFSFDKTCDILGLEMRTVPYGKNYTVDCDKMAEMVDKNTISVSAIAGTTEYGMIDDVERIAKIALENDLFFHVDAAFGGMVIPFLPNPAPFDFEVPGVSSISLDPHKMGMSTIPCGCLLLREPEQFGTLNVDTPYLTVKKECTLAGTRPGADVAGAYAVIKLLGREGFRAVVAGCMENTRRLIEGMEAFGYTRAVDPVMNVATFEAGPVPKGWIVSHTRAGHLRFVVMPHVTRDVIENFLADVAKIN
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.