PharMolix/UniProtQA huggingface dataset:
Protein: EIF3K_ASPCL
Sequence: MGVAFDKCDTRPAHIDAILNGLDRYNPETTTVFQDYVAQQCEDRTFDCYANLALLKLYQFNPHLLQAETATNILAKALTVFPSPAFSLCLALLPAHTQPFPTADADASQTSDFVESVQKLARLSTLLESAQYAQFWSTLNSDDLYADLVADVAGFEELVRIRIAVEVGKAFREINAEVLEQWFDLRSREALEKFVTEVCGWEVDKAGPNGTVVKVPSNKENEVRSEVKSEHVGVEMFGRVIRRGFEQAA
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit K, eIF3k, eIF-3 p25.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit K family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_FRANO
Sequence: MLDKIWYRSKPNLLSRVLQPISLVFIDIANKRKIKQQLKQYKSKIPIIVVGNISVGGTGKTPVVRMLAQQYLAQGKKPAIISRGYGAKADNYPFEVTSGTLATQCGDEPAMLFDALQAQVPIVIAPERVQAVKYIEKNFPDTDIIISDDGLQHYKLARDKEIVVVDAIRMFGNKLCLPAGPLREPIERLKEVDQIIVIGNCSDKDKELLKNYKNVTYAKVVATEFVNILTAKKVAKTEFNHQNVIAIAGIGNPTKFFKTLEESAINITAKKVFKDHHKFTQSDFEGIDSDITVVMTYKDAIKCKNFAKANWWYLDIALDINV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: SRP54_META3
Sequence: MLDKLGSNINNALSKIKNATFVDKKLVKEVIKDIQKALIQADVNVKLVFAMSKEIERKAIYESAPKGLSKKDHIIKIVYDELVKLLGEEGQKLELDPKNKNIILLVGIQGSGKTTSAAKLARTLQKRGFKPALIAADVYRPAAYQQLKQLSEKIHIPLHGDPTKTKTPMEITEEGLKQFKKNDVIIIDTAGRHKEESGLLEEMKEMKEKFNPEEIILVIDGTLGQQAKNQAKAFKDAVENIGSILITKMDGSAKGGGALSAVAEIGAPIKFIGTGEKVDDLEPFDPKKFISRLLGMGDLDSLLEKTEDIIDDDTEESLDAMMRGKFTLNELYSQLEAISKMGSMKQLMAMIPGMGTNLPKGAADITEHKLKKYKIIMDSMTSTEKENPDIIKTSRMKRIAKGAGVKQEEIKELLKYYSTTKNAFQNMKSGKMLKMGGPMGKIMRQLMYKE
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
What are the official names of this protein?
Signal recognition particle 54 kDa protein, SRP54.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: RL7_MYCBO
Sequence: MAKLSTDELLDAFKEMTLLELSDFVKKFEETFEVTAAAPVAVAAAGAAPAGAAVEAAEEQSEFDVILEAAGDKKIGVIKVVREIVSGLGLKEAKDLVDGAPKPLLEKVAKEAADEAKAKLEAAGATVTVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y2021_RUEPO
Sequence: MIVTTTPNVEGRRITAYKGIVVGEAIMGANVVRDVFASITDIVGGRSGAYESKLQDARETALSELEGRAVALGANAVVGVDLDYEVVGQSMLMVSASGTAVVLD
What are the official names of this protein?
UPF0145 protein SPO2021.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: EPHB6_RAT
Sequence: MASENTAGSGSRVAGMVYSLWLLVLGPSVLALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDDQRRLTRTFEACHVAGLPPGSGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQADEPDSPDSISAWHLKRWTKVDTIAADESFPASSSSSSWAVGPHRTDQRVGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVKLFSYTCPSVLRAFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGRWMVAVGGCRCQPGHQPARGDKLCQACPEGSYKALPGNVPCSPCPARSHSPDPAAPVCPCLQGFYRASSDPPEAPCTGPPSAPRELWFEVQGSALMLHWRLPQELGGRGDLLFNVVCKECGGHKEPSSGGMCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTSHEVPSAVPVMHQVSRAANSITVSWPQPEQTNGNILDYQLRYYDQAEDESHSFTMTSETNTATVTRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPEKLSLVIGSILGALAFLLLAAITVLAVIFQRKRRGTGYTEQLQQYSSPGLGVKYYIDPSTYDDPCQAIRELAREVDPTYIKIEEVIGAGSFGEVRRGRLQPRGRREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTRSRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHSPQGSSSLLRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMSDQEVLNAIEQEFRLPPPPGCPTGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGSSGDRPSQALLNPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLSTFSDVAQLSLEDLPGLGITLAGHQKKLLHNIQLLQQHLRQPGSVEV
What is the function of this protein?
Kinase-defective receptor for members of the ephrin-B family.  Binds to ephrin-B1 and ephrin-B2.  Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2.  Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity).
What are the official names of this protein?
Ephrin type-B receptor 6, Tyrosine-protein kinase-defective receptor EPH-6.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: Y095_MYCS2
Sequence: MSSLRTDDDTWDIATSVGSTAVMVAAARAGETERDDALIRDPYAKILVAGAGTGVWETVLDSEFAAKIENLDPEAAAIFAHMGNYQAVRTHFFDAYYREAADAGIRQIVILASGLDSRAYRLDWPAGTTVYEIDQPKVLEYKSATLREHGIEPVAQRREVPVDLRFDWPTALHDAGFDASLPTAWLAEGLLMYLPAEAQDRLFELVTELSAPGSRIAVETAGVAATDRREAMRERFKKFADQLNLSSALDIQELVYDDPDRADVAEWLDAHGWRARGVHALDEMRRLDRLVELPDDPDRAAFSTFVTAQRL
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase MSMEG_0095/MSMEI_0092.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: DNAJ_FRATT
Sequence: MQQKCYYEILNVSKTASGVEIKRAYRKLAMEYHPDRNPGDKEAEIKFKEISEAYEILSDDSKRSRYDQFGHAGVNQQSGFGGTGGFGGFEDIFDTFFGGGTSRGSNRSRASRGSDLEYTLEITLEEAFFGVEKEITIPRMESCDSCDGTGSKSRSKTTCHACHGQGTIRRQQGFFAFEQTCPVCNGTGYSITDPCDACYGNGKVKKQKTLKVKIPEGVDNGDRIRLQGEGDSGSNGAMNGDLYVQIIIKEHKIFERRDINLYCEMPISFTKACLGGDIKVPTLDGEVVLKVVPETQTGKVFRLREKGMKSLRGHRRGDLLCKVVVETPVNLSAEQKELLEKFADSLGEDYQSKHAPKSKTWFDNVKDYAKKFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A7590_ARTBC
Sequence: MKSAAILALLAQALAVTAQPVEGDRTPGTRTLDLPNFPGGSVPTRGVEKRADLPPDNGGGNAPDPDKVHIVGVTYGGTGCPDGTVSHVLSDDRQIMTLIFDQYVAQIGPGVNTKENRKNCQLNINLRYPGGFQFSVFSADYRGYANLEKGVSGTQKSIYYFSGQTEQTSTSTTWKGPIDKDYILHDEANQTSTVWSPCGANGALNINSQVRLTATDRNARGILTNDSVDTSFKQIVHVRWQQCTN
What are the official names of this protein?
Uncharacterized secreted protein ARB_07590.
What are the subcellular locations of this protein?
Secreted.
Protein: AIRP2_ARATH
Sequence: MRKSFKDSLKALEADIQFANTLASEYPEEYDGGYVQMRLSYSPAAHLFLFLLQWTDCHFAGALGLLRILIYKAYVDGKTTMSLHERKTSIREFYDVLFPSLLQLHGGITDVEERKQKEICDKRYRKKDRTDKGKMSEIDLEREEECGICLEIRNKVVLPTCNHSMCINCYRNWRARSQSCPFCRGSLKRVNSGDLWIYTCSAEIADLPAIYKENLKRLLIYIDKLPLVTSDPNLVPYAPLPR
What is the function of this protein?
Possesses E3 ubiquitin-protein ligase activity in vitro when associated with the E2 enzyme UBC8 in vitro (PubMed:21969385, PubMed:28626006).  Plays combinatory roles with AIRP1 in the positive regulation of the abscisic acid-mediated drought stress response (PubMed:21969385).  Plays a positive role in abscisic acid- and high salinity-regulated seed germination through the ubiquitin-proteasome-dependent down-regulation of ATP1/SDIRIP1 (PubMed:28626006).
What are the official names of this protein?
E3 ubiquitin-protein ligase AIRP2, Protein ABA INSENSITIVE RING PROTEIN 2, AtAIRP2, RING-type E3 ubiquitin transferase AIRP2.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL21_ACET2
Sequence: MYAVIETGGKQYKVQEGDVLFIEKLANEEGSTVTFDKVVAVSKDDKVSFGTPFVSNASVTAKVLCHGKGKKIIVFKYKPKKGYRRKQGHRQPYTKIQIEKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: SRY_PUSHI
Sequence: MFGVLNSNDHRAAVQQRNIPAFGRTSFEPWTDNPTSNYRCETGGNGRDSGQNRVRRPMNAFMVWSRDQRRKVALENPQMQNSEISKQLGYQWKMLTEAEKWPFFEEAQRLQAMHREKYPDYKYRPRRKALPQKSDKLLPAASSSMLCRQVLVDEKWYPFTYRDSCSRAAHSRMEDQLSSSQPVNIANWLLQQEHHYRSTSLRDSPETLAAHLSADPPFYPKEQLGLSDAYFP
What is the function of this protein?
Transcriptional regulator that controls a genetic switch in male development.  It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.  Involved in different aspects of gene regulation including promoter activation or repression.  Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.  SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending.  Also involved in pre-mRNA splicing (By similarity).  In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
What are the official names of this protein?
Sex-determining region Y protein, Testis-determining factor.
What is the protein family that this protein belongs to?
Belongs to the SRY family.
What are the subcellular locations of this protein?
Nucleus speckle. Cytoplasm. Nucleus.
Protein: POL1_RCMV
Sequence: MYMLTFEPGLCVAGIIRQVRSNPFMHVVQAYARTTETYREDIEMTKSMLKLKADEPLLVMSIVAAAMDFQTMVMAPIEMEASEFLYGFYAERMSYIVTNRGMSELHEYIQLQCQRHLLVKVEIDGQYLVQEHEYEAQGFNIKRVKELITDVATWVPKKVKGMIGWSVDAVLDSFQEYFYKVITERIPMAMKVCSWVATVWDQIKTWIEDAMTAMSSFLQGCNELLTWGLATLAACCALNVLERILIFMEFLDESIDIAGIFLRTGVVAAACYHFSSTAKGFTEMMSVLSVATTAVAAVVCANYFGGSKTKKVNAQGNPVDLLERIAAGLSSISQDSLVSLGKSCSAINSIATSYGHLRNFAGRVLTMLRDFAWKILGLETRFLADAALVFGEDVDGWLQRISALREAYVSKAYSSQDEVFEMNVLLERGYKMRHLMATGSRVSPAIGNMLMQGLADLERLHRNAAVQGVKGVRKIPFTVFAHGNSRCGKSLLIGKLISDFQEHKGLGEDTVYSRNTTETHWSGYRRQPIVVIDDFAAVESDISAEAQLINLVSSTPYSVVMAAIEEKGMTFDSQFIFASTNFLEVSPNGKIRCDDAFRNRRHVLIDVKLKPEVEYQSDDFTANQSYNILEHSHGRYNVVATFDNYEELLAYCLTKHEQHEAEQEANLAKLRRTNKFESHFKKFEQVLQLSTYFSSSIERIKREALATTDGADDYHLLYVVPRNGSYLHVAANKDFQIQQWYGPVEEVAEEDILRASERMLLGAYEFLLLSTELNVVVKNHLPELICTDNYDHNLEFCGVVGDPVYHQQLLKNIRALKPWHRAVLFGIGTLMGAKNPTPWYKRMWEGIKDVLYKAYSTEISQWPVPLKITCGIVLVGIVGAGFWKTVSVLTNAGNGAGLVGAAVNSFSVVSTAEAQSRKPNRFEVQQYRYKNVPLTRRSWGNAQMSLDQSTVSILNKCHAKFIIASQHAQIVLVPGRRFIGYSHFFCNLKHPLMVQIETADRTYFHRYQPENMEYIEDSELCVYHSSCLEDISHSCWDLFCWDPDKELPKKFSADFVSCKYNTWTKSVEPTWANVDAEVIKEDFTICDGEYRNTVSTSIRYEAPTVMSDCGSMIITNVGGKTKIVGIHVAGRDNKIGMASLLPPLLPCAQAQGAEKYFNFYPIEYDAAEGIARVGELKPKLYIPLPKKTSLVKTPEEWHLGTPCDKVPSILVKGDPRLADTVHADYDPCLSGLTKYSTPMSPLDSVLLGETCQEILDEWFDCLPEGFELGEVTINEALNGVDGVDYMDRIPLATSEGFPHVMSREQGEKGKQRFVQGDGHIVSLIPGTSVHEAYETLSRTIATEVPTLVGIECPKDEKLPFRKVFTKPKTRNFTILPMEYNILVRQYFLNFVRFIMKKRDVLPCQVGINPYSMEWSIVASRLKSQGNDILCCDYSSFDGLLSKQIMEMMADMINRFCGGGTLICAKRKNLLMACCSRLAISRDSVWRIECGIPSGFPLTVICNSIFNEILVRYHYKLLLQEHNAPNMYVQSFKNLISMVTYGDDNLISVNAVVKPYFDGTKLKQAMARNGIIITDGKDKTSATLEFRRLEDCDFLKRGFLKRSSVLWDAPEEKASLWAQLHYVNVNNCEMQVAYMTNLVNVLRELYMHDPTEMVEFRRLALKSIPWLNTTDLPTLYQVKEFYAEQRLRNIPDHNDSLDMLTSVDLLGPAILGEGVPQEALVLSELLEVRDLRYHTVPDNDNGKEVWILFNTMYPQKLLPSNCHSFTWNCGQGRGGLPTQHWLATNVTRTDSKLNKLIRTAVAANKKIVLATKDNILPINVIAVLLAARNKVMPSLATNALLTYVIGAAKKLNFLTSECQFAFFNV
What is the function of this protein?
Replicates the viral genome.
What are the official names of this protein?
RNA1 polyprotein, Genome polyprotein B, P1.
What are the subcellular locations of this protein?
[Putative helicase]: Host membrane; Single-pass membrane protein. Host cytoplasm, host perinuclear region. SUBCELLULAR LOCATION: [RNA-directed RNA polymerase]: Host endoplasmic reticulum. SUBCELLULAR LOCATION: [Protease cofactor]: Host cytoplasm, host perinuclear region.
Protein: URE1_STAAN
Sequence: MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVADEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAATELPLTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_RUTMC
Sequence: MVEENKIVKKVIVTKKPTIKKAPVKAAFKKEVVVKNATVIKKTQTSSKRNTVNITLVKSFHGRLPSHRATIVGLGLKRINHIKELKDTPEIRGMINKVAYLLKVED
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PYRF_ACIBY
Sequence: MSIIVALDAKSQYDALKIVEQLDPTLCRVKVGKELFTHEGPSVVKKLQEENFEVFLDLKFHDIPNTTAQAVCAAADLGVWMVNVHASGGRKMMETCVERLKAGNYQTQLIAVTVLTSMGREDLKDIGLDIEPVEQVKRLAKLTKESGLDGVVCSAQEAKILRELIGQDFSLVTPGIRPEGSNADDQKRIVTPKQAMLDGSTHLVIGRPITNAENPTEMLKSILASIA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RL22_LISIN
Sequence: MASEVTSAKAVAKTVRIAPRKARIVIDLIRGKQVGEAIAILKYTPRSASPIIEKVLKSAIANAEHNYDLDINNLVVEEAFVDEGPTLKRFRPRAQGRASAINKRTSHITVVVSEVKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SPIKE_ADE03
Sequence: MAKRARLSTSFNPVYPYEDESSSQHPFINPGFISPDGFTQSPNGVLSLKCVNPLTTASGSLQLKVGSGLTVDTTDGSLEENIKVNTPLTKSNHSINLPIGNGLQIEQNKLCSKLGNGLTFDSSNSIALKNNTLWTGPKPEANCIIEYGKQNPDSKLTLILVKNGGIVNGYVTLMGASDYVNTLFKNKNVSINVELYFDATGHILPDSSSLKTDLELKYKQTADFSARGFMPSTTAYPFVLPNAGTHNENYIFGQCYYKASDGALFPLEVTVMLNKRLPDSRTSYVMTFLWSLNAGLAPETTQATLITSPFTFSYIREDD
What is the function of this protein?
Forms spikes that protrude from each vertex of the icosahedral capsid.  Interacts with host receptor CD46 to provide virion initial attachment to target cell.  Fiber proteins are shed during virus entry, when virus is still at the cell surface.  Heparan sulfate might also play a role in virus binding.
What are the official names of this protein?
Fiber protein, SPIKE, Protein IV.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae fiber family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Anchored to the pentons, protrudes from the virion surface.
Protein: FDC1_YEAST
Sequence: MRKLNPALEFRDFIQVLKDEDDLIEITEEIDPNLEVGAIMRKAYESHLPAPLFKNLKGASKDLFSILGCPAGLRSKEKGDHGRIAHHLGLDPKTTIKEIIDYLLECKEKEPLPPITVPVSSAPCKTHILSEEKIHLQSLPTPYLHVSDGGKYLQTYGMWILQTPDKKWTNWSIARGMVVDDKHITGLVIKPQHIRQIADSWAAIGKANEIPFALCFGVPPAAILVSSMPIPEGVSESDYVGAILGESVPVVKCETNDLMVPATSEMVFEGTLSLTDTHLEGPFGEMHGYVFKSQGHPCPLYTVKAMSYRDNAILPVSNPGLCTDETHTLIGSLVATEAKELAIESGLPILDAFMPYEAQALWLILKVDLKGLQALKTTPEEFCKKVGDIYFRTKVGFIVHEIILVADDIDIFNFKEVIWAYVTRHTPVADQMAFDDVTSFPLAPFVSQSSRSKTMKGGKCVTNCIFRQQYERSFDYITCNFEKGYPKGLVDKVNENWKRYGYK
What is the function of this protein?
Catalyzes the reversible decarboxylation of aromatic carboxylic acids like ferulic acid, p-coumaric acid or cinnamic acid, producing the corresponding vinyl derivatives 4-vinylphenol, 4-vinylguaiacol, and styrene, respectively, which play the role of aroma metabolites (PubMed:20471595, PubMed:25647642).  Not essential for ubiquinone synthesis (PubMed:20471595).
What are the official names of this protein?
Ferulic acid decarboxylase 1, Phenacrylate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family. UbiD-like/FDC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_MYCMM
Sequence: MSEKGRLFTSESVTEGHPDKICDAVSDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVTTTAKEAFADITNIVRERILDIGYDSSDKGFDGASCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDAQGAGDQGLMFGYAINDTPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDRVPVRLDTVVISTQHADDIDLVKTLDPDIREQVLKTVLDDLAHDTLDASAVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGSEAVDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVDLPWERLDKVDDLKRAI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSIE_ECO8A
Sequence: MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLADVLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRF_HALH5
Sequence: MIRPLIIALDVENRQNMQELLKTLPKPLFVKVGMELFYSEGPAVIEQLKDEGHQVFLDLKLHDIPNTVKRAMRQLATLGVDIVNVHVAGGVNMMAAAREGLEAGTVDGRNRPKLIGVTQLTSTNEAMLQKELLIQSNMNGAVSHYARLAKEAGLDGVVSSAQEVPIIHEHCGPSFLTVTPGIRLKEDDKGDQTRIVTPEEARTLGSWAIVVGRSITAAPDPAAAYEIIRKQWEG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SECY_RICPR
Sequence: MGQNFSKKSSNDLVNRIIFTLFMLIICRFGSFIPIPGIDSIALNSVAEKNQFGILGMFNMLSGGSLGRMSIFALAIMPYITASIIIQLMSVAYKPLENLKKEGETGKRKINQLSRYLTVLLASFQAYGVALSLESMVTNTGPVVILAGFFFRVTTVITLVVGTILLMWLGEQITQRGIGNGTSLIIFIGIISGVPSAIISMFELSRKGALSPLIAITVCIGVVLLIAIIIFFEKAQRKLLVQYPKRQVGNKIYGGEATHMPLKLNTSGVIPPIFASSILLFPTTLASFSNSNSDTMSMLTYYLGHGKPVYILLYVVLIMFFSFFYTAIVFNSEETANNLRKYGAYIPGKRPGKNTSDYFDYILTRLTVIGGIYLSVICVIPELLMNKYVISLSLGGTSFLIVVNVVLDTMTQIQTYLFSSKYEGLMKKIKLKN
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NHAA2_SACD2
Sequence: MAQQETAGGVLLIAASILALIFANSYLSGFYNGVLNLPLVVAIGAFEISKPLLLWVNDGLMALFFLMVGLEVKREVLEGHLSQPSQVVLPGLAALAGVAFPAIIYASFNWQDPTALRGWAIPSATDIAFALGVFSLFGRHLPVSLKLFLLSVAIFDDIAAIVIIALFYSHELSTLSLLVAGIGIVMLFVLNRLKIRHVSPFMFVGLVVWAAVLKSGVHATLAGFVIAWFIPLKHKNIHDEPMLLSLEHALQPWVAYFILPFFAFVNAGVHLGGIGLDTLTAPVTLGIIVGLFVGKQLGIFSVCWLSIKLRIAKLPEGATWRELYGVCLLAGIGFTMSLFIGSLAFEGANSEMVASVKLGVLFGSLLSAICGALILTNSRKIK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CBPZ1_PLAF7
Sequence: MLFKNEDSGNGVYCFTYNNFSDVTISDILNIRNDNKNNDNEDNKQDDEEKNDEDDNKSNLLLEENEENKRQGDKPFEDLSLFSFKNNEQCYDNIKMQQAILNSSYEKNVKNIVKIVYHEDCKLLYENTDIHVELPSIVYGRNRNKNNDVVNKCNQYNDDDYTNKCNQYNDDDYTNKCNQYNDDDYTNKCNQYNDNDYTNKCNQYNDNDYTNKCNQYNDVRKITNLKYFINHNWKNINLINEKLFLKNLKELEEILNYNFLHICKNKCKQYNKKRKNERHFSYHDNFLSHYIIYKKNKFIKHNKNEHINGNHYDAHESTNTYDEEKTREKHNNKNNNMKYCLNKYPYDNVNAPLNLSCPWYEKKIENIYCLNIPGYKYKYKYICPSMSKMNDEKIKELYIPKGHILFNSKFESGNLKYVIKEENDKEVYSLFLNPDIRMNEKKNQWFYFSASYVPNEYYTNELYKMKMCNKDINHIGDNMNVVYNYMNGTGNNINNIVNNLDSTVNYMNSTGNNINNIVNNLDSTVNYMNSTGNNINNIVNNLDSTVNYMNSTGNNINNIVNNLDSTVNYMNSTGNYLNRKNNNHLSYTNWSGQRCMNQYLNDINNDEIDTNLDGNRKYSLDACDKFTVRNVRKLEKPFTVRFKIENMAKPFFLYKYGHSPLSFSECKYKIENIQWERNSYDIKYIKNSSCKHYNIKKNSMEYYNYNTYTLEFSYDFTYAYDTVYFASSYPYTYSYLSEYLCLIRNLLKDHPTINYIEERLCKTSCGFDCPVLCITNYDRMEEYNKEELKESVEKKQNIVEANNTCDEKLVDGMDISSNAIRKEIKKKGYILTSKKLDKNRVVNNLFVDMKNGCTRGCASGCTNGCANGYTNGYTNRYTKGCTKGCTNEYSNDNMCKECLDIKNICYQEEKEKCDIIKYNDDKDYSHNCCYEECYNMKREKKKFVCCLSDKCNSFLNEQIKRRRSIMGWNILRNRIKCCKNKMYTSNDFMKTFDSLLKKVYVCKGENKKNNGTKIIKRFEEKYDNNLLFKRKDEKRSLSASPKKKKKKKKKIIVLTARVHPGETNSSYAIHGFIAFIISNNIYAHILREKFIFIIIPMLNIDGVILGNNRYCYNGFDLNRQWSNPIGYIHPTIYSAKLLMKNISENNKIIFFCDFHSHSRKYNCFIFGNEGSYNYVKNKKMCEVFPEIYSHTLPWFALVDTVYKADNENKGSARLISGKEFSLDCSYTFEISLFGIQIRKDFNIMYDEKKDIFYVQNYFEGYQNGDDNIKGGDNIKGGDNIKGDDNINGDDNIKGGDNIKGDDNIKRDDNFQRDDNFQRDDNFQRGDNFHRGDNFHRDDIYDKMNKHYINNNYYYDKNSYDFLYFDENLLFMTGVSFGICLFKFINFLSYHKSSICRRTCEEKEKEHISTETCGILCAKNNKDDEEKCNESKKQNHDAFKTGNSLEFDKGEEHLLSDTHRMVNTFLCNSMNKSKNKNKNKKGYNYILNKYGFIKLKSSKKHIEEVKRIRKLKKKKYMVKEVYELGRKIKQNKYYHNYPFGLYKVNINDVIRILNKINMDDPNGKYKGPGFNNSVDMKKKIKNKNESKTEKKSKTENKSKSKSKNKSKSKNKSKRKKVIVIL
What are the official names of this protein?
Putative zinc carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.