PharMolix/UniProtQA huggingface dataset:
Protein: CYOE_PHOPR
Sequence: MAKSQALGNAPLTSTVAENATTRSTSKPNIWRDYLTMTKPKVVAMLLLTALVGMCLAVPGIPPAKAVILGLIGIGFQSAAAAAFNHVLDRRLDTQMARTYNRPLAKGRIETWKAVVFASTLMVMGFVILLELNALTAWLTMASLVGYAVVYTVWLKHATPQNIVIGGIAGAAPPLLGWTAVTGQLDPHALLLVMLVFTWTPPHFWALAIHRRDDYAKAGIPMLPVTHGIEFTKTMVLLYTVMLFIVGLLPWLTGMSGGVYLVGSSLLNLGFIGYALKLKFADSKGHAWATFKYSIWHLLALFVVLLGDHWITSLMF
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HYDA_GEOSE
Sequence: MTKLIKNGTIVTATDIYEADLLIQDGKIAVIGRNLDESGAEVIDATGCYVFPGGIDPHTHLDMPFGGTVTKDDFESGTIAAAFGGTTTIIDFCLTNKGEPLKKAIETWHNKATGKAVIDYGFHLMISEITDDVLEELPKVIEEEGITSFKVFMAYKDVFQADDGTLYRTLVAAKELGALVMVHAENGDVIDYLTKKALEDGHTDPIYHALTRPPELEGEATGRACQLTELAGSQLYVVHVSCAQAVEKIAEARNKGLNVWGETCPQYLVLDQSYLEKPNFEGAKYVWSPPLREKWHQEVLWNALKNGQLQTLGSDQCSFDFKGQKELGRGDFTKIPNGGPIIEDRVSILFSEGVKKGRITLNQFVDIVSTRIAKLFGLFPKKGTIAVGADADLVIFDPTVERVISAETHHMAVDYNPFEGMKVTGEPVSVLCRGEFVVRDKQFVGKPGYGQYVKRAKYGALMADQDVVKMS
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin.  Has no activity on dihydropyrimidines.
What are the official names of this protein?
D-hydantoinase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
Protein: SYP_STAAT
Sequence: MKQSKVFIPTMRDVPSEAEAQSHRLLLKSGLIKQSTSGIYSYLPLATRVLNNITAIVRQEMERIDSVEILMPALQQAELWEESGRWGAYGPELMRLQDRHGRQFALGPTHEELVTSIVRNELKSYKQLPMTLFQIQSKFRDEKRPRFGLLRGREFIMKDAYSFHADEASLDQTYQDMYQAYSRIFERVGINARPVVADSGAIGGSHTHEFMALSAIGEDTIVYSKESDYAANIEKAEVVYEPNHKHTTVQPLEKIETPNVKTAQELADFLGRPVDEIVKTMIFKVDGEYIMVLVRGHHEINDIKLKSYFGTDNIELATQDEIVNLVGANPGSLGPVIDKEIKIYADNFVQDLNNLVVGANEDGYHLINVNVGRDFNVDEYGDFRFILEGEKLSDGSGVAHFAEGIEVGQVFKLGTKYSESMNATFLDNQGKAQSLIMGCYGIGISRTLSAIVEQNHDDNGIVWPKSVTPFDLHLISINPKKDDQRELADALYAEFNTKFDVLYDDRQERAGVKFNDADLIGLPLRIVVGKRASEGIVEVKERLTGDSEEVHIDDLMTVITNKYDNLK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_GUITH
Sequence: MSRYRGAVIKIIRRLGELPGLTRKTTTRTSRPGQHGTQARKPSEYAIRLEEKQKLRFNYGLTEKQLLQYVRTAKRIKGSTGEALLQLLEMRLDNVIFRLGMAPTIPAARQLVNHGHIKVNNTRVSIPSYQCKAGDMISIRQHPKSQSIVKNYLQFPGLANMPNHLQIDKDNLTGKINGIIERDWVALNELLIVEYYSRKG
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TCYB_BACSU
Sequence: MFLNNLPALTLGTAIPWDLVQQSFWPILSGGIYYTIPLTILSFIFGMILALITALARMSKVRPLRWVFSVYVSAIRGTPLLVQLFIIFYLFPAFNVTLDPFPSAVIAFSLNVGAYASEIIRASILSVPKGQWEAGYTIGMTHQKTLFRVILPQAFRVSIPPLSNTFISLIKDTSLASQILVAELFRKAQEIGARNLDQILVIYIEAAFIYWIICFLLSLVQHVIERRLDRYVAK
What is the function of this protein?
Part of the ABC transporter complex TcyABC involved in L-cystine import.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
L-cystine transport system permease protein TcyB.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CATH_RAT
Sequence: MWTALPLLCAGAWLLSAGATAELTVNAIEKFHFTSWMKQHQKTYSSREYSHRLQVFANNWRKIQAHNQRNHTFKMGLNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPSSMDWRKKGNVVSPVKNQGACGSCWTFSTTGALESAVAIASGKMMTLAEQQLVDCAQNFNNHGCQGGLPSQAFEYILYNKGIMGEDSYPYIGKNGQCKFNPEKAVAFVKNVVNITLNDEAAMVEAVALYNPVSFAFEVTEDFMMYKSGVYSSNSCHKTPDKVNHAVLAVGYGEQNGLLYWIVKNSWGSNWGNNGYFLIERGKNMCGLAACASYPIPQV
What is the function of this protein?
Important for the overall degradation of proteins in lysosomes.
What are the official names of this protein?
Pro-cathepsin H.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: PSBL_JASNU
Sequence: MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL7_NEIG1
Sequence: MAITKEDILEAVGSLTVMELNDLVKAFEEKFGVSAAAVAVAGPAGAGAADAEEKTEFDVVLASAGDQKVGVIKVVRAITGLGLKEAKDIVDGAPKTIKEGVSKAEAEDIQKQLEAAGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: BHE22_MESAU
Sequence: MERGLHLGAAAASEDDLFLHKSLGASTAKRLEAAFRSTPPGMDLSLAPPPRERPASSSSSPLGCFEPADPEGAGLLLPPPGGGGGAGGGGGGGGGGGVSVPGLLVGSAGVGGDPNLSSLPAGAALCLKYGESAGRGSVAESSGGEQSPDDDSDGRCELVLRAGGADPRASPGAGGGGTKVVEGCSNAHLHGGAGLPPGGSTGSGGGGSGGGGGGGSSSKKSKEQKALRLNINARERRRMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQGQAISAASLPSSAAAAAAAAALHPALGAYEQAAGYPFSAGLPPAASCPEKCALFNSVSSSLCKQCTEKP
What is the function of this protein?
Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors.  Despite the presence of an intact basic domain, does not bind to DNA.
What are the official names of this protein?
Class E basic helix-loop-helix protein 22, bHLHe22, Beta-cell E-box transcriptional activator 3, BETA3, Class B basic helix-loop-helix protein 5, bHLHb5.
What are the subcellular locations of this protein?
Nucleus.
Protein: VPS10_ASHGO
Sequence: MVGMLFVWQTFLFVWACAAAVEVGEKPRPVIDIVRDVDNLGSIWQFKGTNTLIRHQGREILVRHGGDQWSTVKKFDQGVNTVEVDPYYPERRAFAWLENNELYKTDDCGKTWARVMHVEAEPGENLQRYSVYSNPDNYKYLMVTSHFERKDSSPVLAESYEKQWVSQDGGKTIAPLGHPDPGVYRLCHFLRQARNHDVAKDSTILCIEHDAQKHTAVLYRTDDFGKSKQALDSFDDEIVSSVGLLGKYILVTTTEDAYNKHAVQHVWVSRDGDKFQKIIFPTHIRDNFFRAVTTSTGNQIIFSIPAGKHSHSRKNALYANYISDSSGIQFHAVADSLDERYKELGPVMALDANGTLSMVARKSSTEDQVTLLSYDYGYSWQPMHLAEGEDHKALGCSKGGKECELPVQLSQLVSSSGLVGHGESATSGILMGIVLKKRGSRGPRKHKYLSVISRDYGLTWSVAFEYPVLSFAGNYGNILLACPYNPGDDGDPEEEIYYSLDQGHTWEEHHIEGKYEFVRVHSAISDGSSTAFSFLAVGDDQNTIVVDCIFTDIHNGKECTDGDMEEYKLRNGNCLNGARYTINKRKSEAACLLKNDPSVINPLVKPCDCTNADYECSLGFLGLPDKGCTADLGMLRSAGACKDNPRELMPMHKIKGNECTKDLNIEPVKVDCSAVQNRPDIEVTAHVFKTQFETYQYFNSAEDDSLMVLTKDKRALISHDSGKTFKMLDTLGSGAELITFNRYFGDLAYIFASDDVLYITDDRGYHFYAVDLPEVRHLFLPLAFHAKDNQTFIYFGGKDCEKLGPKCHSTAYITTDGGRNFREMLTGAVSCEFVGSIYSHPANKDMIMCEIENKKERRNILLRSTDEFRTSDKVFDSIIGFHTTGDFTAIAVSEGRQQVSSYLTIDGVHFNESRFPPDFVAPEKQQSYSVLSAHEGAIFLHMSKSLVKHKEYGTLVKSDSNGIDFVVLKDGVNSNAEGLVDFETPEGLDGVILINVVENLDQVQKGKAKAKHLKTAISFNDGVDWKYLSPPGKDSSGKKYPCHGKNRAKCSLNLHGYTERKDLRDTYSSGSAIGYMLGVGNVGEHLLPYEQCSTFLTTDGGVTWTEVKSTPHQWEFGDRGSIIVLVPDGVKTNSITYSVDAGRSWQDFKFADEEVIIDDIITVPYDTSMRFLLISKEHLRGKSKTYAISFAHIFKRQCEFHPGGGRHNGDFEYTSIKHPDYKCLFGKEVEFLKRIKYDCFIGNASYTKDYRTSRICPCTRQDFECDYNYIRTSDGTCKLPSGVKPEAPSAVCERNRDLVEYFQPTGYRKIPLSKCEGGLKLQRTDSPHPCPGKEKEFYEKYPSSTNASSVVFWWLLLTMVLLVPLWVIYDRGIRRNGGFSRFGEIRLDDDDLIEENGLDRAINKVVKVGAYGVAGLFGFLLLLKSKAGARIRRFRESVSSRRGPSYSSLISDQFLDDANDLLVGHDNDANNLNAFLDEDGQHFDVDDEIEGADQASYHDDVDLGRTSE
What is the function of this protein?
Functions as a sorting receptor in the Golgi compartment required for the intracellular sorting and delivery of soluble vacuolar proteins, like carboxypeptidase Y (CPY) and proteinase A.  Executes multiple rounds of sorting by cycling between the late Golgi and a prevacuolar endosome-like compartment (By similarity).
What are the official names of this protein?
Vacuolar protein sorting/targeting protein 10, Carboxypeptidase Y receptor, CPY receptor, Sortilin VPS10, Vacuolar carboxypeptidase sorting receptor VPS10.
What is the protein family that this protein belongs to?
Belongs to the VPS10-related sortilin family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Prevacuolar compartment membrane; Multi-pass membrane protein. Note=Cycles between the Golgi apparatus and the prevacuolar compartment.
Protein: TEDC2_MOUSE
Sequence: MLGVKGNYLLPADCAHRLVAELQGALDSCADRQRQLERSLRVSRRLLQVWEPARTPSPVPETKEEDPSPACAPSSQDLEELELLTQALEKAVRVRKGVSNAGQRDRTPTLTSKAATSGAAAASHPRAPSRGGSRVLGTRSTKGIQRATAPPKDYPEHRLRSKGDKTHVRTQDQTTGYGPDLRDQQMTPSSAHHTTELFALKEKGTLLQLPEDFRKAVSRNSCLWAQLNSARTNDSTDATRAAKTQFLHKLQMASGCSSHRPSATEVEAHARILRKACMLLRLRMQKELAIAPTDWMQEYRCLLTLEGLQTVVGQCLHRIQVLQAAVTEQLPGECLAETRTQASSVCGGEVDSACSPELLLYASTEELQTLATLKLQVALLHQQIHLEKVLMAELLPLINTQDPGGPPWLALCRAAYSLLCEGGERFLTVLRDDPAD
What is the function of this protein?
Acts as a positive regulator of ciliary hedgehog signaling.  Required for centriole stability.
What are the official names of this protein?
Tubulin epsilon and delta complex protein 2.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: YSH1_CANGA
Sequence: MDVKERSNQFRFFSLGGGNEVGRSCHIIQFKGKTIMLDAGIHPAYQGMASLPFYDDFDLSIVDVLLISHFHLDHAASLPYVMQKTNFKGRVFMTHPTKAIYRWLLRDFVRVTSIGSQSSNAEDDNLYSNEDLIESFDKIETIDYHSMIDVNGIKFTAFHAGHVLGAAMFQIEIAGLRVLFTGDYSREIDRHLNSAEVPPLPSDILIVESTFGTATHEPRLHREKKLTQLIHSTVNKGGRVLMPVFALGRAQELMLILDEYWSQHKEELGSNQIPIFYASNLARKCLSVFQTYVNMMNDNIRKKFRDSQTNPFIFKNIAYIKNLDEFQDFGPSVMLASPGMLQNGLSRDLLERWCPDEKNLVLITGYSVEGTMAKYLLLEPDTIPSVSNPEVTIPRRCRVEELSFAAHVDFQENLEFIEQINASNIILVHGEPNPMGRLKSALLSNYASFKGTEDEVHVHNPRNCYELDIECKGVKVAKAVGNIVDEIKRTEEEVVKPENDAGQSKEGIEEFTGKTQDVRKDAEGEGAIISSILVSDEKNFDLNLVSLSDLREHHPELSTTVIRERQTIQVDCKKELIYWHICQMFGDVSVLIDDDNVTNTKETKLETSRGMLVLQIMGAIRLTVQHNKAILEWTQGLISDTIADSIIAILMSVDSAPVSVKKSSNSCSHGHEHATPILSQPSETDKIKQVAELFKTQFGDSFTLILNKDDDNDTAEEKEDDEFVKGLITIGKNTASINFTDMCVVECNSNPLKGRVESLLKIGIDMVSSLC
What is the function of this protein?
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
What are the official names of this protein?
Endoribonuclease YSH1, mRNA 3'-end-processing protein YSH1.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: OPAK_NEIGO
Sequence: ASEDGGRGPYVQADLAYAYEHITHDYPEPTAPNKNKISTVSDYFRNIRTRSVHPRVSVGYDFGGWRIAADYARYRKWNNNKYSVSIKELLRNKGNGNRTDLKAENQENGTFHAVSSLGLSAVYDFKLNDKFKPYIGARVAYGHVRHSIDSTKKTTEVTTILHGPGTTPTVYPGKNTQDAHRESDSIRRVGLGAVAGVGIDITPNLTLDAGYRYHYWGRLENTRFKTHEASLGVRYRF
What is the function of this protein?
Implicated in a number of adherence functions.  OPA proteins are implicated in pathogenesis and are subject to phase variation.
What are the official names of this protein?
Opacity protein opA57.
What is the protein family that this protein belongs to?
Belongs to the opacity porin family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: SYH_STAAT
Sequence: MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFESTDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPIKLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLKLVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIKTAPRITDFLNEESKAYYEQVKAYLDDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNYDGAITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFIVTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELENNKIDVKNMTTGESETIELDALVEYFKK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA1_BRADU
Sequence: MKIGINSDMGEGFGNYRICDDEALMSIVSSANVACGFHAGDPIIMDRMVRLAKQKGVEVGAHPGLPDLLGFGRRVIQMDAAELEKHMVYQIGALQAIAANAGHRVTHVSFHAAMGNMVNADPDMADVVARAIATINRDFIVFSQPDAEIVRAARKVGLRTLTLFLADRAYDENGHLVSRKLPNSVVTSTEAVAERVKRFLDSGTVQTIEGKSIKVEARSILIHSDTPGSVNLAGTVRRVIEQGGGEVTPATVLLN
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A 1, 5-OPase subunit A 1, 5-oxoprolinase (ATP-hydrolyzing) subunit A 1.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: NIS1_COLHI
Sequence: MQFRASIAAAAGLFALANARIYGIAFPETVKAGDEVEAVITTENYIQAVQDIAIAFGIATEASAYPETLGNALGSFYLGPEESNTLENITETVTIPAGLAPGQYVVAAGLYSLYGASSSPTLSHYNVTVTVGNVTSETYVGSQR
What is the function of this protein?
Secreted effector that induces necrotic lesions in Nicotiana benthamiana (PubMed:22352720).  Interacts with the host receptor-like kinases (RLKs) BAK1/SERK3 and BKK1/SERK4, inhibits their kinase activity and suppresses INF1-induced pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) in N. benthamiana (PubMed:30584105).  Also interacts with the host receptor-like cytoplasmic kinase (RLCK) BIK1 and inhibits its kinase activity, thereby inhibiting PAMP-induced ROS generation (Probable).  In PTI, phosphorylation relaying by RLKs and RLCKs is critical for the initiation of downstream signaling (Probable).
What are the official names of this protein?
Necrosis-inducing secreted protein 1, Secreted effector NIS1.
What is the protein family that this protein belongs to?
Belongs to the NIS1 effector family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm.
Protein: QUEA_HELHP
Sequence: MTYFDPKIQESDFALSSYDYTLPFSAIAQNPANPRERAKLLIYQRDSGRIIHSDFYHFCDFVPKDTLLVFNDTRVIKARIYAHKLDCNTQKLSDKTFEIFYHKPLQSTSSAIPLFLVQIKGRVKCGDKLLINTDSTNPFLIAQVQECLDNGLRVVSFMQNEHALEYIQVLDMLEKYGHTPLPPYIKREDSCQDAHFYQSVFSKQLGSIAAPTASLHFSKESIESIKAQFETCFLTLHIGAGTFMNVESADIRHHLIHKEFFSLSPQSAAAIQNAHKVLCIGTTSARCVEYYARYKILQGECDIFLYPSKSFKRVDYLLTNFHLPKSTLMMLVSAMVGREKCLELYKLALEKGYRFYSYGDGMLIL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMM_BACLD
Sequence: MLKQWFNVGKIVNTHGVKGEVRVISRTDFPEERYKPGNALYLFLEGKDEPVQVTVSAHRLHKQFHLLQFKEVETLTEAEKLKNALIKVPEDQLSQLAEDEYYFHEIIGCDVFSEDGDLIGKVKEILTPGANDVWVVARPGKKDALIPYIDAVVKEINVADKTIKIHIMEGLLDE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15A_PICMA
Sequence: MGAYKYIEELWKKKQSDVMRFLQRVRCWEFRQLPGIVRVTRPSRPDKARRLGYKAKQGYVVYRVRVRRGGRKRPVPKGIVYGKPKNQGITQLKFQRSLRSVAEERAGRKLGGLRVLNSYWINQDSTYKYYEIILVDQAHSAIRKDPRINWICNAVHKHRELRGLTSAGKKYRGLRGRGHLYHKARPSKRATWKRNNTLSLRRYR
What are the official names of this protein?
60S ribosomal protein L15-1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: PRRA_MYCTO
Sequence: MDTGVTSPRVLVVDDDSDVLASLERGLRLSGFEVATAVDGAEALRSATENRPDAIVLDINMPVLDGVSVVTALRAMDNDVPVCVLSARSSVDDRVAGLEAGADDYLVKPFVLAELVARVKALLRRRGSTATSSSETITVGPLEVDIPGRRARVNGVDVDLTKREFDLLAVLAEHKTAVLSRAQLLELVWGYDFAADTNVVDVFIGYLRRKLEAGGGPRLLHTVRGVGFVLRMQ
What is the function of this protein?
Member of the two-component regulatory system PrrB/PrrA that is involved specifically in early intracellular multiplication of Mycobacterium and is essential for its viability.  Upon phosphorylation by PrrB, functions as a transcription regulator by direct binding to promoter regions of target genes to positively regulate their expression.  Autoregulates its own expression.
What are the official names of this protein?
Transcriptional regulatory protein PrrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPG_ECO27
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CLPP_HALHL
Sequence: MSDTQQSAPDIFNTGLVPMVVEQSARGERAYDIFSRLLKERVIFLVGPVEDYQANLLVAQLLFLESENPDKDVHLYINSPGGSVTAGLAIYDTMQFIKPDVATLCVGQAASMGALLLAAGAEGKRHALPNSRMMIHQPLGGFQGQATDIDIHAREILSMRDRLNTILAHHTGQDIETIRQDTDRDNFMAAEAAAQYGLIDRVLTSRGASE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: L1CAM_MOUSE
Sequence: MVVMLRYVWPLLLCSPCLLIQIPDEYKGHHVLEPPVITEQSPRRLVVFPTDDISLKCEARGRPQVEFRWTKDGIHFKPKEELGVVVHEAPYSGSFTIEGNNSFAQRFQGIYRCYASNKLGTAMSHEIQLVAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAAPPRIYWMNSKIFDIKQDERVSMGQNGDLYFANVLTSDNHSDYICNAHFPGTRTIIQKEPIDLRVKPTNSMIDRKPRLLFPTNSSSRLVALQGQSLILECIAEGFPTPTIKWLHPSDPMPTDRVIYQNHNKTLQLLNVGEEDDGEYTCLAENSLGSARHAYYVTVEAAPYWLQKPQSHLYGPGETARLDCQVQGRPQPEITWRINGMSMETVNKDQKYRIEQGSLILSNVQPTDTMVTQCEARNQHGLLLANAYIYVVQLPARILTKDNQTYMAVEGSTAYLLCKAFGAPVPSVQWLDEEGTTVLQDERFFPYANGTLSIRDLQANDTGRYFCQAANDQNNVTILANLQVKEATQITQGPRSAIEKKGARVTFTCQASFDPSLQASITWRGDGRDLQERGDSDKYFIEDGKLVIQSLDYSDQGNYSCVASTELDEVESRAQLLVVGSPGPVPHLELSDRHLLKQSQVHLSWSPAEDHNSPIEKYDIEFEDKEMAPEKWFSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSESVVTPEAAPEKNPVDVRGEGNETNNMVITWKPLRWMDWNAPQIQYRVQWRPQGKQETWRKQTVSDPFLVVSNTSTFVPYEIKVQAVNNQGKGPEPQVTIGYSGEDYPQVSPELEDITIFNSSTVLVRWRPVDLAQVKGHLKGYNVTYWWKGSQRKHSKRHIHKSHIVVPANTTSAILSGLRPYSSYHVEVQAFNGRGLGPASEWTFSTPEGVPGHPEALHLECQSDTSLLLHWQPPLSHNGVLTGYLLSYHPVEGESKEQLFFNLSDPELRTHNLTNLNPDLQYRFQLQATTQQGGPGEAIVREGGTMALFGKPDFGNISATAGENYSVVSWVPRKGQCNFRFHILFKALPEGKVSPDHQPQPQYVSYNQSSYTQWNLQPDTKYEIHLIKEKVLLHHLDVKTNGTGPVRVSTTGSFASEGWFIAFVSAIILLLLILLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
What is the function of this protein?
Neural cell adhesion molecule involved in the dynamics of cell adhesion and in the generation of transmembrane signals at tyrosine kinase receptors.  During brain development, critical in multiple processes, including neuronal migration, axonal growth and fasciculation, and synaptogenesis.  In the mature brain, plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
What are the official names of this protein?
Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, growth cone. Note=Colocalized with SHTN1 in close apposition with actin filaments in filopodia and lamellipodia of axonalne growth cones of hippocampal neurons.
Protein: CRGD_RAT
Sequence: MGKITFYEDRGFQGRHYECSTDHSNLQPYFSRCNSVRVDSGCWMLYEQPNFTGCQYFLRRGDYPDYQQWMGFSDSVRSCRLIPHAGSHRIRLYEREDYRGQMVEFTEDCPSLQDRFHFNEIYSLNVLEGCWVLYEMTNYRGRQYLLRPGEYRRYHDWGAMNARVGSLRRVMDFY
What is the function of this protein?
Crystallins are the dominant structural components of the vertebrate eye lens.
What are the official names of this protein?
Gamma-crystallin D, Gamma-D-crystallin, Gamma-crystallin 2-2.
What is the protein family that this protein belongs to?
Belongs to the beta/gamma-crystallin family.
Protein: RM53_HUMAN
Sequence: MAAALARLGLRPVKQVRVQFCPFEKNVESTRTFLQTVSSEKVRSTNLNCSVIADVRHDGSEPCVDVLFGDGHRLIMRGAHLTALEMLTAFASHIRARDAAGSGDKPGADTGR
What are the official names of this protein?
39S ribosomal protein L53, mitochondrial, L53mt, MRP-L53, Mitochondrial large ribosomal subunit protein mL53.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mL53 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: 1433F_MOUSE
Sequence: MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLALLDKFLIKNCNDFQYESKVFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEHMQPTHPIRLGLALNFSVFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEEAGEGN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner.  Negatively regulates the kinase activity of PDPK1 (By similarity).
What are the official names of this protein?
14-3-3 protein eta.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.