PharMolix/UniProtQA huggingface dataset:
Protein: RL39_SULIA
Sequence: MSRNKPVAKKFRLAKALKANSPIPIWIVLKTRGRVRYNPLRRNWRRNDLKV
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: RL13_MESFL
Sequence: MKQTTLIAAKDIKKNWYIVDAAGQNVGRLSTEVARILRGKHKVDFTPHMNNGDHVIIINAEKVLFTGKKESDKTYYHHSMHPGGLRRRTVAVQRELDATKILERSIRLMLPKNVQGRNQFRALHVFVGENHPYAAQKPEVLTFVKKGDNK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: UB2E1_MOUSE
Sequence: MSDDDSRASTSSSSSSSSNQQTEKEGSTPKKKESKVSMSKNSKLLSTSAKRIQKELADITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQWTKRYAT
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  Catalyzes the covalent attachment of ISG15 to other proteins.  Mediates the selective degradation of short-lived and abnormal proteins.  In vitro also catalyzes 'Lys-48'-linked polyubiquitination.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 E1, (E3-independent) E2 ubiquitin-conjugating enzyme E1, E2 ubiquitin-conjugating enzyme E1, UbcM3, Ubiquitin carrier protein E1, Ubiquitin-protein ligase E1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSA2_BACAA
Sequence: MRKFDKSIAAFEEAQDLMPGGVNSPVRAFKSVGMNPLFMERGKGSKVYDIDGNEYIDYVLSWGPLIHGHANDRVVEALKAVAERGTSFGAPTEIENKLAKLVIERVPSIEIVRMVNSGTEATMSALRLARGYTGRNKILKFIGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGVAKNTITVAYNDLESVKYAFEQFGDDIACVIVEPVAGNMGVVPPQPGFLEGLREVTEQNGALLIFDEVMTGFRVAYNCGQGYYGVTPDLTCLGKVIGGGLPVGAYGGKAEIMRQVAPSGPIYQAGTLSGNPLAMAAGYETLVQLTPESYVEFERKAEMLEAGLRKAAEKHGIPHHINRAGSMIGIFFTDEPVINYDAAKSSNLQFFAAYYREMVEQGVFLPPSQFEGLFLSTVHSDADIEATIAAAEIAMSKLKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_SHEFN
Sequence: MAKLTKRARVIREKVDATKLYDINEAVVLLQELATAKFVESVDVAVNLGIDPRKSDQNVRGATVLPHGTGRDVRVAVFTQGANAEAAIAAGAELVGMEDLAEKVKAGEMNFDVVIASPDAMRVVGMLGQILGPRGLMPNPKTGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVTFTTEQLKENLESLVSALKKAKPAVAKGIYVKKISISTTMGAGVAIDQGSLEEAK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PKHM1_MOUSE
Sequence: MLSVENGLDPRAAIQVIKKKLVGSVKALQKQHVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKHTHQKALPQPVFWPLLKAITHRHIVSDLEHLVFINTDVGRCRAWLRLALNDGLMECYLKLLLQEPARLCEYYQPTALLRDAEEAEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLSLSGLCPLSELDPLTTSGAELQRKESLDSISHSSGSEDIEVQHSGHKIRRNRKLTASSLSLDTASSSQLSCSLNSDSCLLQENGPKSPDHSEEPMSYDSDLGMANTDDPDRSLQEVLSEFSKAQVNSAPSSGPNQEPDTPMFQTPLSLHSLATSTHLHFEGSEELFPAHKSSGTSSGGHKHQLLPQETPDEKQLGTAQAGPAQSTSDQQPSSPVGGAAGQGSGPWKALEYGRVGPKLVVSSPTSPKGKSWISEDDFCRPPQEPALKSAAGLCTSPVQDTPESRAALHGPFSQGPRKSCSLGALDKACVPSQACGNAQPAPAPAPAPAPAPAPAPGVTQDHKNFCVVHRRQMGLSNPFRGLMKLGTVARRGAMGIWKEFFCELSPLEFRLYLSDEERTCVESCSLLRCEAVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNIQYPDQAEDAPEAPPDSLPPYSTLLPEPAGAQGMQLDWTSAQVPEPDAIKESLLYLYADRTWVPYIFSLSLESLKCFRVRNNEKMLSDSHGVETIRDILPDTSLGGPAFFKIITAKAVLKLQAKNTEEATHWRDLVRKVLASYLESAEEAVTLGGSLDEKCQEVLKFATRENGFLLQYLVAIPTEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDFCHQDDASVIPARIIHNWDLTKRPVCRQALKFLAQIRAQPLINLQLVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELCKRLSHRNYLLESPHRFSVADLQQIAEGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICHHQDIIFPFEFDTTVRCAECRTVFHQSCQAVVRKGCPRCARRRKYQEQNVVS
What is the function of this protein?
Acts as a multivalent adapter protein that regulates Rab7-dependent and HOPS complex-dependent fusion events in the endolysosomal system and couples autophagic and the endocytic trafficking pathways.  Acts as a dual effector of RAB7A and ARL8B that simultaneously binds these GTPases, bringing about clustering and fusion of late endosomes and lysosomes.  Required for late stages of endolysosomal maturation, facilitating both endocytosis-mediated degradation of growth factor receptors and autophagosome clearance.  Interaction with Arl8b is a crucial factor in the terminal maturation of autophagosomes and to mediate autophagosome-lysosome fusion (PubMed:25498145).  Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (PubMed:27777970).  May be involved in negative regulation of endocytic transport from early endosome to late endosome/lysosome implicating its association with Rab7.  May have a role in sialyl-lex-mediated transduction of apoptotic signals (By similarity).  Involved in bone resorption (PubMed:27777970).
What are the official names of this protein?
Pleckstrin homology domain-containing family M member 1, PH domain-containing family M member 1.
What are the subcellular locations of this protein?
Autolysosome membrane. Endosome membrane. Late endosome membrane. Lysosome membrane. Note=In case of infection colocalizes with Salmonella typhimurium sifA in proximity of Salmonella-containing vacuole (SCV).
Protein: YT24_CAEEL
Sequence: MDSSNPSSLPLEKSSGNVQKGKLLNIWSRCIAQPSSFLGSSISRFWANADIKNRVCSAAIGRVNFVSKCLKKFPEVSLSCNISASLSLNTGKEKVKNEDLEKQERCHKVAMIEYEIQNLERQLKKRQF
What are the official names of this protein?
Uncharacterized protein B0304.4.
Protein: RL35_LACP7
Sequence: MPKLKTSKAAAKRFKVTGTGKLKRMKAGKQHILTKKSQKTKRNLRKATMMDPSNEKNMKKILPYL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: NOP2_MOUSE
Sequence: MGRKLDPTKKEKRGPGRKARKQKGAETELVRFLPAAGDENSKRLSSRARKRAAKRRAGSVDVPKPNKSPGIKTLPGELSKGAVQARGKKRPAPIQNSDGDEEEDSGEDDVVTQGDLWGSEDSDEDMVDDYGAASNSEDEEEKLLPIERAALKQKAQDATAGVLWNEEDTDEDEDDDGVSPESHPRKDDKAEGDLQINVEDEEAFVLPPAGETDQDGQAPDLQRVHKRIQDIVGVLRDFGAQREEGRSRAEYLSRLQKDLATYYSYGDFLLSKLMELFPLSELIEFLEANEVPRPITLRTNTLKTRRRDLAQLLINRGVNLDPLGKWSKSGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAPGGKTSYIAQLMKNTGVILANDANADRLKSVVGNLHRLGVTNTIISHYDGRQFPKVVGGFDRVLLDAPCSGTGVISKDPAVKTNKDEKDIQRCAHLQKELLLSAIDSVNAASKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFQARRFHPTLRSTRRFYPHTHNMDGFFIAKFKKFSNSIPQPHAGNSAAATPTEPDLKDQVTPKSENGSQPTKKARGAVKAKQQLLRQPHSKKPFQKLNGIAKGPGLSTEPSVPDAQVSTRPSQSAGNADVNSKRKRSEKLKQRGPKWKPSKEAAVPKPSAPSRVEDSGTPVPTPSEIRAAPRPKDCAPSLGKAKKKQKGKQQLAQQPANGAAPLKEDAVSKGPSAPFVSPHSSTRPPPAKRRKSMTKGNSQPLLS
What is the function of this protein?
Involved in ribosomal large subunit assembly.  S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C(5) position of cytosine 4447 in 28S rRNA.  May play a role in the regulation of the cell cycle and the increased nucleolar activity that is associated with the cell proliferation.
What are the official names of this protein?
Probable 28S rRNA (cytosine-C(5))-methyltransferase, Nucleolar protein 1, Nucleolar protein 2 homolog, Proliferating-cell nucleolar antigen p120, Proliferation-associated nucleolar protein p120.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: T2R42_PAPHA
Sequence: MATELDKIFLTLAIVEFIIGMLGNVFIGLANCSEGIKNQKVFSVDFILTCLAISTIGHLLVILFDSHVAGLAPHLYATDRVVRPVTVLWHMTNHLTTWLATCLSIFYFFKIAHFPHSLFLWLRWRMNRVIAILLTLSLFLLIFDCLVLEMFIDISLNIIDKSNLTLYLDESKTPYDKLFLLKTLLSLNSFIPFSLCLTSLLFLFLSLVRHTRNLKLSSLGSRDSSTEAHRRAMKMVMSFLFLFIVHFFSLQVANWTFCILGNNKYTQFVMLALHAFPSCHSFILILGNSKLRQTAVRLLWHLRNYTKRPNPLPL
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 42, T2R42, T2R55.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPOB_MYCCT
Sequence: MAYKIRKINRNVERRDYTKVSMNLSLPNLIGIQTETFEWFKTKGIQEVLDEFFPILSFDGSSVLTLENWGFKEPRLSVRQAREESKIYDAPIYANLKLSVNKTEEIQKEFDGVDQEDTLKVLTHWLEEKTGNGNITFKQQSQNSYFFEITIKKSEKPDLIQIDIIEDKKTSLICNVSIYKSGEVFLGDFPLMTEAGTFIINGSQKVIVSQLVRSPGAYFNKELNRKTGEMIYFADIIPSRGTWLEYETDSKKIGSDAINPLYVKIDKSRKTTATSLLLAFGISKDDILNIFDNDEVLVETLQQDSIIGDFKIDWSNQVQEIYKKIRQGETATSEGASKFINSILFDKRKYDLTKAGRFKLKQKLSIKNRILNKVIAEDILDANNNVLIAKDTEVTKNNIQEISKILDQDVMSIDLKYLSDIPGNRKVQKIRVYKDSELKTDTTCLIGLTNSSNEEFITVADILSTVSYLLNLKYNIGEIDDIDNLGNRRVRTVGELLQNQFRMGLNRIDKNVKEKLATSDLYKVKTSTIINAKPLTAIIGEFFNLSQLSQFMDQINPLSELTNKRRLTALGPGGLSRDRAGLEVRDVHPSHYGRICPIETPEGPNIGLINNLSTYARVNEYGFITTPYRKVINGIIQNDQVEYLTADQEKNFIIAQSNVNQDENGKILDEIIVSRFNGDDYMAKVEEIHYIDVSPKQIVSVATSGIPFLENDDANRALMGANMQRQAVPLIKPESPIVATGIEFEAARDSGEAIVAKEDAIVKYVDSKTIITDGESGIRTYILSDYERSNNGTSLTQSPIVKVGDVVKKGEIIADGPSMDQGELAIGQNVVVAFSTYNGYNFEDAIVMSERIVIDDRFTSIHIDEYTLEVRNTKQGQEEVTREIPNMSEQAKRHLDAEGIVAIGTEVKVGDVLVGKVTPKGQVQLSPEDKLLHAIFGEKSRNVKDNSLRVPNGGEGIVQSIKRFKAKSALNPDGIELPADIIEVIKVYVVQKRKIQEGDKMSGRHGNKGIISRILPIEDMPHLEDGTPVDIILNPQGVPSRMNIGQILEIHLGMAAKKLNQKVITPVFEGLNEKELEEIMAEAGMTNYGKVTLIDGQTGEPFDKPIAVGVMYMLKLSHMVDDKIHARNVGPYSLITQQPLGGKAQNGGQRFGEMEVWALEAYGAAHTLREILTIKSDDIKGRSKTYEAIVRSKRIPEPGIPESFNVLSKEIMGLGFNMYMIDETGEKSAINAYDKKDFEIDNYDDEILIKTDNLYIDDQDVDAEFEDLTYVDENDILNSFELDNEEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DAPH_LACLA
Sequence: MEAQKLSAQEIIQFIGNAEKKTRVKVTLSGMPSFKAAGFLAENGRPNFKALANKGIQVLGDFHTHYSLKIIIGDWQAVRPLLSGLTENKDYTLELEGRNSAVPLLDTREINARIEPGAIIRDQVTIGDSAVIMMGAIINIGAEIGEGTMIDMGAILGGRATVGKNSHIGAGAVLAGVIEPASAEPVRVGDNVLVGANAVVIEGVQVGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDEKTQQKTALEDALRNL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: PEBA_PROMA
Sequence: MNKLMLQDLHNNLKRRIISHGGKPIEVENGMSERFSHKQDTVIKSWLWDVPGFRRWRVTRMDAGDKLQVLNSVAYPAYTNDKPILGIDILWFGLKRKLVAVLDFQPLVQEERYFCRYYKDLQILKNRFVDFNSQKTMKIYDSNKYFSPWVLLYNGSFDDLQCSLAKILDEFLHAYWQVDNNNSREYIKIIPSKVEQLHINYDIYSAERDPAHGLFKSYFGQTWADQFVREFLFPHSHLTAD
What is the function of this protein?
Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge.
What are the official names of this protein?
15,16-dihydrobiliverdin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: SYL_RUBXD
Sequence: MSETFAKRASRRGYDPRAIEERWQRRWAETGLYKTDEDPSKPKHYALTMLPYPSGDLHVGHWYAMTPSDTRARFMRMRGYRVFFPIGFDAFGLPAENAAIKRGIHPRDWTYSNIERMRGQLRQMGTMFDFDAEVVTCDPEYYRWNQWFFLKFYEKGLAYREKAPVDWCPSCNTTLAREQVVGPDRRCERCDTPVIKRNLAQWLFKITDYAEELLDFSEIEWPERVKALQRNWIGRSEGAEIEFEIEGYGGVTVFTTRPDTLFGATFFVVAPEHPAVESITTPERGEEVRAYVERAARMSEIDRADVTREKTGVFTGAYAVNPANGERIPVYVADYVLMGYGTGAIMAVPAHDERDFEFAKKHGIEIRTVIAPPDWDGSPLERAYVGEGQMVNSGPFDGTPSAEGREKVTGWLRERGVGRPAVNYRLRDWLISRQRYWGTPIPIVYCERCGTVPVPEEDLPVLLPEDAEFMPTGESPLKFNDEFRKTECPRCGGPAERETDTMDTFVDSSWYQYRYLSPHYEEGPFDPERGSRWLPVDQYTGGIEHATMHLLYTRFFTKVMRDLGLVDFDEPMLRLFNQGVILGPDGNRMSKSRGNVVNPQEYVDRYGSDVLRCYLMFIGPWDEGGPWDPGGIEGVARWLRRAFTLVAGGDVSEAEADPGELSRRTHRLVKRVTEYLEGFRFNTAIAALMEHTNYLLAVKGEVGEEEWREAMRSFLLVLAPFAPHHAEEMWEILGEEYSVHEQGWPSWDEELVREETVTLVVQVNGKLRDRVEAPAGVDEGRARELALSSERVRAHVEGRELRKTVYVPGRLINLVVS
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_BURM7
Sequence: MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRNSIPEALPDDAGRVLLPSVVRYLDKGGRRIGHAAKEEAAIDPRNTIVSVKRFMGRGKAEVEGAANAPYEFVDAPGMVQIRTVDGVKSPVEVSAEILATLRQRAEDTLGDDLVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAIAYGLDNGAEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDFDHLLFEHVLAQAGLEVAALAPEDVRLLLDRVRGAKEALSAAPQARVDVKLSTGEKLAQTITRDTFAALVEPLVQRTLGPTRKALRDAQVSAADIKGVVLVGGATRMPVIRDAVAKYFGQPPLVNLDPDQVVALGAAIQADLLAGNRSGGDDWLLLDVIPLSLGVETMGGLVEKIIPRNSTIPVARAQEFTTFKDGQTAMAIHVVQGERELVSDCRSLARFELRGIPPMTAGAARIRVTYQVDADGLLSVFAREQHSGVEASVVVKPSYGLGDDDIARMLEDSFKTAEVDMRARALREAQVEAQRLVEATEAALVADGDLLDASERATVDALVASLRALAPGDDADAIDTATKALAEGTDEFAARRMDKSIKRALAGRKLDEI
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PCKA_ALIF1
Sequence: MEHKKAALLDLTQYGLTGVTDVLRNPSYEQLFEEETRPDLEGYERGVMTELGSVAVDTGIFTGRSPKDKYIVKDDTTKDTLWWSDQGKNDNKAITPAVWDDLKSLVTTQLSGKRLFVIDGFCGANPDTRLNVRIITEVAWQAHFVKNMFIRPTEAELENFEPDFVVMNGAKVTNPNYEKHGLNSENFVAFNLTERVQIIGGTWYGGEMKKGMFAMMNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRQLIGDDEHGWDDDGIFNFEGGCYAKTIRLSKEAEPDIYNAIRRDALLENVTVRSDSSIDFNDGSKTENTRVSYPIYHIDNIVKPVSKAGHAKKVIFLTADAFGVLPPVAKLTPEQTKYHFLSGFTAKLAGTERGITEPTPTFSAAFGAAFLTLHPTQYAEVLVKRMEAAGAEAYIVNTGWNGTGKRISIQDTRGIIDAILDGSIDQAKTKNIPVFNLEVPTSLPGVDASILDPRDTYTDPLQWDSKAEDLAQRFIKNFAQYTDNEEGKALVKAGPQL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOM_MOUSE
Sequence: MFHQVWAALLSLYGLLFNSMNQCPEHSQLTALGMDDTETPEPHLGLWYFIAGAASTTEELATFDPVDNIVFNMAAGSAPRQLQLRATIRTKSGVCVPRKWTYRLTEGKGNMELRTEGRPDMKTDLFSSSCPGGIMLKETGQGYQRFLLYNRSPHPPEKCVEEFQSLTSCLDFKAFLVTPRNQEACPLSSK
What is the function of this protein?
Probably involved in lipid transport.  Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity).
What are the official names of this protein?
Apolipoprotein M, Apo-M, ApoM.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_CLOBL
Sequence: MKKEEIIQAIKEMTVLELNELVEACEEEFGVSAAAPVAVAGAGAAAAGAAEEKTEFDVVLTDAGSEKIKVIKAVREVTGLGLKEAKALVDGAPKTLKEAASKEDGEAIKAKLEEVGAKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: GCSH_LEPBP
Sequence: MADTQAKDGYYYTEKHEWVKVEGDVALIGITDFAQNALGDIVFIDLPKPGKQIKAKDSLGTIESVKAAEDLYSPISGEVVETNATLGSNPQAVNAEPFDTWMVKLKNIQTSELGGLLTAAQYKEYVSKLD
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: ISPF_PSEPF
Sequence: MRIGHGYDVHRFAEGDFITLGGVRIAHGFGLLAHSDGDVLLHALSDALLGAAALGDIGKHFPDTDPQFKGADSRVLLRHVVSLIHAKGWKVGNVDNTIVAQAPKMAPHIESMRALIAADLQVELDQVNVKATTTEKLGFVGREEGIAVHSVALLLRA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RUVC_COXB1
Sequence: MDNPRRIIIGIDPGSRITGYGIIWSQGSKQGCIAFGQIKTDNDSLNFRLHQIERELRDLILIHRPHEAAIEQVFTFHNHQSALKLGQARGAALVATAACALPVAEYSARQIKQAVVGYGAATKAQVQHMVHLLLQLEKAPPADAADALAIALCHATSSRLSEKLMQAKGTLT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: COAX_MARMM
Sequence: MLLAIDCGNTNTLFAIHDGNDWVAQWRSGTDSTRTADEHAVWLSQLMGLQGRSFADITACVISTVVPQALFNLRNLSRRYFKAEPVIVGEPGVRMDIEVRLDRPQDAGADRLVNALGARAVYDGALIIIDSGTATTFDVIAADGAFEGGIIAPGINLSMQALHGAAAKLPRVAIAKPARVMGKDTVSAMQSGVFWGYIDLIDGLVQRLKSEYAQPMTVVATGGVVSLFDGASKAIDHYDADLTIRGLLEVWKLNGGADT
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRK1_CAEEL
Sequence: MEIENIVANTVYIKARESGGQKKGKSKKWKNYLQFPHYTECLPLKTEIEVTYAFVVEKQPIGKLLFHEFCQATNSQYHQCCQFLTKVEEYETSDDDGQSRRDLASSIVSLLHSKPEDNPSGSQDEQEFWCSFLSDEVISTCITTADSATHDDEPRSDIFTEPYRLTCQYLTDAPFKEFAESMYFHRFLQWKWLEKRPVDKHTFRLYRVLGKGGFGEVCACQVRASGKMYALKKLEKKRVKKRHAETLSLNEKQILQRINSPFVVSLAYAYETKDALCLVLTLMNGGDLKFHLYNLMPGGFDEKRVQFYAAEITLGLQHLHSERILYRDLKPENILLDDFGHVRISDLGLAVEIKDNEPIKGRVGTVGYMAPEIVKNERYSYGVDWWGVGCLIYEMIEGKAPFRQRKEKVKREEVERRVREDQEKYSEKFSEAARTLCRGLLHKEPGFRLGCRRVGRPEDGAEEIRAHPFFNTADTVTGREPVPWKKMEAGKVTPPFCPDPRAVYAKDVLDIEQFSTVKGVRLDATDTQFYGKFNTGCVSIPWQSEMIETECFAELNTFHDEDGNVMWNLRPDGINMDERRNGTSKPGFFSRLFRKKNIEVTKSLHDLSHLGVEQQQPPKTSTQTPAVRSSRAASASGRTLVI
What is the function of this protein?
Specifically phosphorylates the activated forms of G protein-coupled receptors.
What are the official names of this protein?
G protein-coupled receptor kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Protein: FEOC_ECODH
Sequence: MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
What is the function of this protein?
May function as a transcriptional regulator that controls feoABC expression.
What are the official names of this protein?
Probable [Fe-S]-dependent transcriptional repressor.
What is the protein family that this protein belongs to?
Belongs to the FeoC family.
Protein: RL15_FLAPJ
Sequence: MNLSNLQPAEGSTHNQNKRLGRGEGSGKGGTSARGHKGAKSRSGYSKKIGFEGGQMPLQRRVPKFGFTNINRIEYQGVNLDNLQLLVDNGIVTDTVDMAVFITSRLATKTEVVKILGRGELKAKLKVSAHKFTATAKAAIEAAGGEAIEL
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: GCSP_XANAC
Sequence: MSQTPSSLRDLEHHSAFVERHIGPNDAEIAQMLDVVGHASLDALTDAIVPGNIKSPAPLALPEAITEEEALAKIRAIASKNQVQRNFIGQGYYGTHTPKVILRNILENPAWYTAYTPYQAEISQGRMEALINFQTLCADLTGMQIANASLLDEATAAAEAMTLAKRSAKSKSNTFFVHDAVHPQTLELLRTRAEPLDIVLRVGTPEEALQAECFGVLLQYPDSFGHIGDHAALADAVHAQGGLVAVATDLLALTLIAAPGEWGADIVVGNSQRFGVPFGFGGPHAAFMACRDAYKRSMPGRLIGVSIDAAGNPAYRLTLQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPDGLVRIARRTHRLAAILAAALRSAGVSVGDRFFDTLHVKAIDADAIHARARAAGINLRAIDSEAVGISLDETTTRADVVALAQLFGATADVDALDAATADALPQGLLRTTPFLTHPVFNTHHSEHELLRYMRSLADKDLAMDRTMIPLGSCTMKLNATAEMIPVTWPEFGAIHPLAPAEQSAGYAQLIDELEAMLVECTGYDAVSLQPNSGAQGEYAGLLAIRAYHRSRGQAHRDICLIPESAHGTNPASAQMCGMTVVVTKCDANGNVDVDDIRAKAEKYSDRLAALMITYPSTHGVFEEDVVAICEAVHAHGGQVYTDGANMNALVGVAKPGKWGSDVSHLNLHKTFCIPHGGGGPGVGPCAVKSHLAPYLPRAGIHAGEGQTAAIHGGGFNSESGNGHSSRIGGMVSAAAYGSASILPISWMYVTMMGSAGLRKATQVALLNANYIAKRLAPHYKTLYTGRNGLVAHECILDVRPLEKTSGIGAEDIAKRLIDFGFHAPTLSFPVAGTLMVEPTESESQHELDRFIDAMIQIREEIRAIEDGRLDREDNPLKHAPHTATQVSASEWTHAYPRELAAFPLPSLKQQKYWPPVARVDNVYGDKNVMCACIPVDAYKEDAEA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: HUT1_CANGA
Sequence: MSKSNSIFPVLFCAAGIYASFLTWALVQEPLTTQVWENSHKRFQCPNVIAVVQAVAAVCVGYFYMRAKGAQRNYGAIAMVRDYAKPLALISFTQSASSPLSQYALQYVDYLTYMLAKSCKMIPVLLVHLIIYRTTISRKKSVVAVLVSIGVTIFTIGGSKGKISGSISGSNDEHFFQKASGFLLLFLSLFMDGLTNATQDKMLKNNRVQMAIQNAETQDKKQQHKVFHTLTGAHMMFALNFFVAIWNIAYLLVIDRGQICNAHAMLKKDPIIVSYLLAYALCGSLGQCFIFYTLELYGSLVLIMITVTRKMMSMLLSIIVFGKTVNATQWLGIVIVFSGITWEALDKRREKKALEAKVQKSE
What is the function of this protein?
May be involved in specific transport of UDP-Gal from the cytosol to the Golgi lumen.  Involved in the maintenance of optimal conditions for the folding of secretory pathway proteins in the endoplasmic reticulum (By similarity).
What are the official names of this protein?
UDP-galactose transporter homolog 1.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.