PharMolix/UniProtQA huggingface dataset:
Protein: RPOZ_TREPA
Sequence: MIFPMQQLIEFQGNIYEITCAATRRAFQLAAVCDPVLDELGGKVVSAAAQQVFSGTVDYRIEPQELG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: BCCP_NEOYE
Sequence: MQITIKKLQDLLSSVQRKKIQTLKLKQGKFELLLNKTYKKVNQEIIPSQKSAVLQNSPSTIIKSINNTKKIFCVNEDRTEYATIVSPMVGTFYHSPAPGEKIFVQVGDEVKFNQTVCIIEAMKLMNEIEAEIEGKIIEILVKDGDIVDCGQALMKVET
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxyl carrier protein of acetyl-CoA carboxylase, BCCP.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y050_HAEIN
Sequence: MLLSASIMLYHLDMFDTQLITENFVMGTNNFPLMAIPFFMLTGEIMKHGGISERIINFATSMVGHIKGGLGYVAIISGLIFAGLSGSAVADTAALGAILIPMMISKKYDGARSTGLICAAGIISVVIPPSIPMIIYGITAGASITKLFMGGTVPGLLMVVGLWVTWKILYRNNDTSLERKQTGKERWVAFKKAFWPLLLPIIIIVGLRGGIFTPTEAGVVAAIYAGIVSIAYKGLTFSKLKDVFIGTIKTTSMVMFVAASAMISAFAITVAQIPTELVQTIKGLTDSPTILMFIIMLFLLLVGCVMDLIPAVLIFVPVLLPVLRAYNIDIAYFGIMMVINLSIGLITPPVGTVLYVGSGISKLGIGALSKGIAPFLFVYAIIMMLIVFFPEIVIVPMNWLS
What are the official names of this protein?
Putative TRAP transporter large permease protein HI_0050.
What is the protein family that this protein belongs to?
Belongs to the TRAP transporter large permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DPOD3_DROME
Sequence: MSLKKALDDCMIDFDRCVLVTDLLEEYKLSYKEVNDVLEAYIKEQEPATKFEKRFLVHGKRKTQGSDSGEDLYSVVLESRMQDWLAKVQDAESQLYSVKIAGGTKAPAAIFKPMQHLEVKLAKVEQRPGAGKIVPSANGTTPHNGVKSEPTKSEPSKSAVKLEPSKSSLKSEPAKSKAEKPVASKSSPEDKKTSPKEQASKAKPAAAKKGSINSFFTAAASKPKDVKATPSKSTSGTVDNFFKKQPAGAKKSPPESEDKSKKDASNSNKKEASKKKSPSPTKKPTTANTSMQLFDEESAESSDEEEKLDMLRRKVIESDNDSDQEKASSSKRRRISDSEDEEQPPKKSADEETIALDEKMDTEPANETYLDEDGFVITQRKPTKAQPANKKVSPKAAAPVNKKKSPPSAAKAGKDAPKTKQAGIMNFFSKK
What is the function of this protein?
Accessory component of the DNA polymerase delta complex and possibly the DNA polymerase zeta complex (By similarity).  As a component of the delta complex, participates in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (PubMed:22532806, PubMed:25826374, PubMed:31100062).  Required to recruit the DNA polymerase delta complex to the nucleus of rapidly dividing embryonic cells, and as a consequence is essential for genome replication during the earliest cell cycles (PubMed:31100062, PubMed:25826374).  Increases the efficiency and processivity of DNA synthesis of the DNA polymerases during mitotic DNA replication and repair (PubMed:22532806, PubMed:25826374, PubMed:31100062).  During development this function is essential for preventing replication stress that results in the formation of chromosomal fragile sites (CFS) such as chromosomal breaks (PubMed:31100062, PubMed:25826374).  Ensures genomic stability by promoting several types of DNA repair mechanisms including repairing broken dicentric chromosomes through homolog-dependent break-induced replication (BIR) (PubMed:22532806, PubMed:25826374, PubMed:31053594).  During homologous recombination (HR) repair, required for maintaining the processivity of the delta complex during break-induced replication; a form of HR that requires extensive DNA synthesis such as the repair of large gaps (PubMed:25826374, PubMed:22532806).  Able to suppress position effect variegation and may therefore have a role in the induction of chromatin state changes that likely include its activities in DNA replication and repair (PubMed:25826374).
What are the official names of this protein?
DNA polymerase delta subunit 3, Pol32 polymerase delta subunit 3.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=During oogenesis, detected in the nuclei of nurse cells, follicle cells, and in the nucleoplasm of the oocyte. In syncytial cell cycles, accumulates in the nucleus during interphase but disperses into the nucleoplasm at the onset of mitosis.
Protein: RS20_STRP6
Sequence: MANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANPSEELFRAASSSIDKAESKGLIHKNKASRDKARLAAKLG
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: SELU_SALHS
Sequence: MQDRQKAQDYRALLLADTPLIDVRAPIEFEQGAMPGAINLPLMMDDERAAVGTCYKRQGADAALALGHRLVCGDIRQQRLEAWKAAYQRFPNGYLCCARGGQRSHIVQRWLQETGIDCPLIEGGYKALRQTAIQATWQLAQKPILLIGGCTGSGKTQLVRQQPNGVDLEGLARHRGSSFGRTLNPQLSQASFENKLAVELLKINARQTLKRWVLEDEGRTIGANHLPECLRERMAQAPIAVVEDPFALRLERLREEYFICMHHDFTHAYGDEAGWQAYSEYLHHGLFAIRRRLGLQRFAELTDTLDRALAEQLSSGSTDGHMAWLVPLLNEYYDPMYRYQLEKKAANIVFRGPWQDVANWLKAQ
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: CSNC_ASPOZ
Sequence: MPIKSFASRLALSLAICGTAMGQKVNGADYNKPDGGPPAKFFQASSSIPVAAIQAAAAKASKVPSHATYPIGQGSTKSTIHSDWAGFSEGAAFSFIADMDVDCDGLNHGCKGNPDGQKETNWGALSAYEVPFIVIPQEFLDANKGTLKGNAVAAVICNGKMFYGIFGDSNGDSPQVTGEASWLMARTCFPKEDLNGNKGHTAADVTYIVFTGDKAVLPSSALNKNYITNFDTLRSMGDSLVGALAKNLNLGGGGGNPPTTLTTTSIPEPTGGSGSCSWPGHCAGATCSSNDDCSDDLTCQNGKCASDGSAETCSWEGHCKGATCSSNDDCSDELACISGICSVDNGVETCEWEGHCEGASCSSHDDCDGNLACKNGKCSA
What is the function of this protein?
Chitosanase catalyzing the endo-type cleavage of chitosan, the deacylated form of chitin.  Chitosanase may be crucial in the degradation of the deacetylated portion of chitin in the fungal cell wall.  Chitoolisaccharides produced by the hydrolysis of partially N-acetylated chitosan are known to have many biological activities, including antibacterial activity, immune-enhancing effects, and elicitor activity.
What are the official names of this protein?
Endo-chitosanase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 75 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCS2_ECOLI
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAATDHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.  However, because of the low catalytic rate, the question remains whether L-cysteine is the actual biological substrate.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: ACEK_DECAR
Sequence: MKISVGLYGTNAHQIALAMIQGFNKHYTLFRQTSREAKTRFEQADWLGVHKAVKERIRFYDDRVDECVERLRNQFDAASIDDTTWQQVKLLYIGLLLNHKQPELAETFFNSVTTKILHRNYFHNDFIFVRPSISTENIEGDDTQTYRSYYAKEDGLRGTVLKIVKDFDWHRPFVDLEHDVEHVYHAVRHFLNGMPPREVNFQIQVLGSAFYRNKAAYIIGKAINGATEYPFTIPVLQNEAGQLYLDTILLDAWRIGLLFSLSRAYFMVDMEVPSGYVQFLRSILPAKPRSELYIMLGLGKQGKTMFFRDLIYHLHHSEDKFIMAPGIRGLVMLVFTLPSYPYVFKLIKDVFGSSKEMDRATVKKKFMMVKQVDRVGRMADTLEFSNVMFPLKRFNDEVLAELQQLAPSCFEVDGDQLIIKHLYIERRMEPLNIHLDRMERANNVERLEHVIREYGSAIREMAQANIFPGDMLWKNFGVTRFGRVVFYDYDEIEYMTDIKFRQIPPAPDFETEMSGEVWYAVSRNDVFPEEFATFLLTSPQVRKIFIKYHKDLLSPRFWLEAQEKIRSGYVEDFFPYPQELRFINRQTDLTEEQ
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_SYNSC
Sequence: MAKTVKKSGPKKAKRNVPNGVAHIQSTFNNTIVSITDTAGEVISWSSAGASGFKGARKGTPFAAQTAAEAAARRALDQGMRQIEVLVRGPGSGRETAIRALQVAGLEITLIRDVTPLPHNGCRRPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PYRD_RHOPA
Sequence: MIRAFDAVSLPLLRWLDPEDAHRLAIQGLKLWPPVKPRPDDSKLAVRAFGLNFSNPVGIAAGFDKNAEAPDALLRLGFGFVEVGTVTPKPQAGNPRPRLFRLERDEAVINRMGFNNEGAEVVLRRLAARAQYGGIVGVNVGANKDSDDRVADYVKLIETFAPLASYFTVNVSSPNTPGLRNLQQAAALDDLLARVIDARERVRAAAGDTPVLLKIAPDLSLGELDDVVHIARSRRVDGMIVANTTLSRSPTLRERTKMNEQGGLSGRPLFRLSTRMVAETFVRAEGAFPLIGVGGIDSGGAALTKIRAGATLVQLYSALVYKGLGLVESIKADLASTLLRTDRDSLAEIVGADAPMITAEEWPV
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PYCC_PSEAI
Sequence: MSKSWNHDRAAKHIDQKIADVEEITIKDYVRDMSLESIPTSTAYRVDGVHMYADIMNLEDMLNITAVEGTECHKRTLRFLDQHYRAVKRILNKVDARRVDFHSQRLHSLFTKPYNTESGAETKRVQRAVATAQLIIDVLAETGDDDEQIPAAKVRIGIDTGLALAVNNGRSGYREPLFLGDPANHAAKLASNNKARGIYLTNNARKAIGLAESDEPEKSALTAIEIKACQDAAKLDVTSDEIVEEWREDLKKNPIGGYQFSRQTPPLRDMDIYSLTPANSKRQEMVSLYADIDGFTAYVADHINEKTDDVVRTLHVIRSELERVVTSDFEGRRVRFIGDCVQALSCDGTAHTTDEEKSVSEATRLAGALRSSFNLAIERLNAEGIETGDLGLAIGFDLGPIAVTRLGAKGNRVRCAIGRSVIESEKRQCACSGVETAIGQVAYDAASKAVQNLFGKSRKTSHLDYNEATEALADDGDASAKQARSEAYAGSAAIIRADERQVQPHSRQKVDGSR
What is the function of this protein?
The pyrimidine cyclase gene of a two-gene Pycsar system, generates cyclic UMP (cUMP) from UTP, has little to no activity on ATP, CTP or GTP (PubMed:34644530).  Expression of this and adjacent effector PaPycTIR (AC P0DV41) probably confers resistance to bacteriophage.  The genes are probably only expressed in response to bacteriophage infection (Probable).  Does not have adenylyl or guanylyl cyclase activity (PubMed:32454240).
What are the official names of this protein?
Uridylate cyclase, Adenylyl cyclase-like protein, PaAClp, Cyclic UMP synthase, cUMP synthase, PaPycC.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. Pyrimidine cyclase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_RALSO
Sequence: MEPTAAPHPHLYLASQSPRRQELLRQIGVRFELLLADGDEDAEALEAVLLGETPDDYVQRVCALKAQAAARRRAARGLPARPILTSDTTVCLGGEILGKPADAADAHRMLRGMSGREHRVLTAVTVVTADGTPMHALSVSQVRFAVLTDVDIARYIASGEPFGKAGAYGIQGRAAAFVAHISGSYSGIMGLPLFETAALLAQAAITL
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_AQUAE
Sequence: MLSLLSSEIFFSAIQYNLSLMEEVRLKKLQELREKGINPYPYRFEVTDFIGNIRKQYEEEPPENYKVRVKGVAKRVSRTENGYMVRLADEKGIEILVFTKEEGLKPKESYTFEGILKRVEGKLSLVEAVLTEEEGEEVYKIKEQFDYDPNFRPVSLAGRLVSMRSMGKAIFGHIQDLTGKIQIYLKKDVIGEEKLKFFNDYIDVGDIVGVRGKLFRTNTGELTVEVEEYQLLAKSLHPLPEKWHGLKDVEVRYRQRYLDLIANPEARRIFMLRTKLITEMRKFFEMHGFIEVETPILQPIASGANARPFVTYHNFLETELYLRIAPELYLKRLIVGGFPRVYEIGKNFRNESVDRTHNPEFTMVEFYAAYWDYHDLIKFTEDMFVYLLEKTLGTLKVKYGEWELDFSPPFKKVRYFDLLKEKTGKDKDFFLKDLEGLRKLAKELEIPDVERMTHAKLLDKVFEKVAEEDLIQPTFVIDFPKILSPLAKTHREDPDLVERFELIIARYEVANAYTELNDPFDQKERFLEQLKEKQMGDEEAMDMDEDFIRALEYGMPPTAGEGIGIDRLVMILANTDSIREVILFPQLKPEKKKKEAP
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AQPB_DICDI
Sequence: MSLKRSDDYQDLEEGIAMEDGGNIKDEEEKPLDPIEEQNKKRWVLIRAVLGELLCTFLFVYVLCATSANFIRLGSPPNPVVGGLSTGFAAVALIYSFADVSGAHFNPAVTFATCVTRKTSITKGLMYVGAQLVGSVLASLILLATFPGNFPGDKNAASAVAIAPSTDANIGNAFLTELVLTFILVYVIFAVAFDTVDNSVKTKVVGKSSSNNLTIYTTSGQTKAGFAPIAIGFTLGFLCFLGGSVSGGAFNPARVFGTALVGNNWTRHWMYWIADFLGAGLAGFAQKFFSSTHK
What is the function of this protein?
Putatively gated water-specific channel, requiring a cysteine residue within the channel.  Impermeable to water, glycerol and urea when expressed in Xenopus oocytes.  Not regulated by pH; channels remain impermeable to water at pH 7. 4 and 5. 2.
What are the official names of this protein?
Aquaporin-B.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Note=Expressed in lamellipodia- like protrusions of the plasma membrane and intracellular vacuolar structures.
Protein: RIBA_ECO8A
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHTPVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: VE7_CRPVK
Sequence: MIGRTPKLSELVLGETAEALSLHCDEALENLSDDDEEDHQDRQVFIERPYAVSVPCKRCRQTISFVCVCAPEAIRTLNRLLSASLSLVCPECCN
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: RS19_BURM7
Sequence: MARSVKKGPFCDAHLLKKVEAAAASRDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: DBP5_YEAS7
Sequence: MSDTKRDPADLLASLKIDNEKEDTSEVSTKETVKSQPEKTADSIKPAEKLVPKVEEKKTKQEDSNLISSEYEVKVKLADIQADPNSPLYSAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDSFEKNKQINAQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYGLMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNSFNILSAIQKYFGDIEMTRVPTDDWDEVEKIVKKVLKD
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP5, DEAD box protein 5, Helicase CA5/6, Ribonucleic acid-trafficking protein 8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: CC107_BOVIN
Sequence: MASVVSLAGTLGLLLVSALPEVLGDRRSPDRRAHPGDAGQVGPAAAEPRRQSPPSKNQRERARSGALPLGALYTAAAVAFVLYKCLQQGKDEAAVLQEEADKKDSLQSEQHLAQLTQQLVQTEQHLNSLMAQLDPLFERVTTLAGAQQELLHMKLQTIHQLLQDSKPNKGVEVPEPEASIPFLEDFCIEEDEEEAGDNQAWEEPLNWNTGTRNLTPPREMQPTLRRRCRKSAAQGLSHSPHWKEGKTVDGLVKQSLFL
What are the official names of this protein?
Coiled-coil domain-containing protein 107.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RBBE_DICDI
Sequence: MNLCLIDPFKQSDVPETVEYYLVDPKNIKSNCASFNRRGTLLAVGCASPIGKILVWDFDTKKIVRTLYHHTGCVNSISWSRNGKKLLTASNDGSLVLWDLATSKILYSLELESPILFAEFHPRNNDLCLIVLQKGTDPILLNFKSSEKTPLNIKSLVTSYIKREENSTGVIPTSVNSNYNGVATFASFNRRGEKIFFGDSCGMISVLDFKSMTIDRQFKVASSNTTVKQIEFSRNHRFMLVSSSDKVLRLISLESTNLYQQMREYQDSVNRMHWKKCCFSSNNEYVVGGMNHKSIHSIFIWSVSGSLVKDLEGPKEGLVDVVWHPLRPIIVSISFTGVIYVWTAYFEENWSSFAPDFQELEENLDYVEDEDEFDAKDSDNENQEVNNNNNNNIGRNPYKKIKTQQELNDKNSEEEEFVDVDHNDRITEFSSDEEEDLFCFSAIDDRYVSNVKFDDPRHPLYEKYQKDKEDSSSTTSNSTISSSSSPSPSSSSTTTTTTTSQKKDETQKKEKSTKKERNSDSKKRK
What is the function of this protein?
Involved in mono-, di- and trimethylation at 'Lys-4' of histone H3.  Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.
What are the official names of this protein?
Retinoblastoma-binding-like protein E.
What are the subcellular locations of this protein?
Nucleus.
Protein: PR1_MEDTR
Sequence: MSFRCFSFALFLLLLTFISHVSASYIPNKKSFKSRSFKNQFLIPQNIARAAVGLRPLVWDDKLTHYAQWYANQRRNDCALEHSNGPYGENIFWGSGVGWNPAQAVSAWVDEKQFYNYWHNSCVDGEMCGHYTQVVWGSTTKVGCASVVCSDDKGTFMTCNYDPPGNYYGERPY
What is the function of this protein?
Probably involved in the defense reaction of plants against pathogens.
What are the official names of this protein?
Pathogenesis-related protein PR-1.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
Protein: RS2_PARPJ
Sequence: MAVTMRQMLEAGVHFGHQTRFWNPKMAPFIFGHRNKIHIINLEKTLPMYNDALKYARQLAANRGTILFVGTKRQSRDTIAEEAQRAGMPFVNARWLGGMLTNFKTLKVSIKRLKDMEAALEAGETERMSKKEALLFEREMAKLVKSIGGVKDMGGIPDAIFVVDVGYHKIAVTEANKLGIPVIAVVDTNHSPEGIDYVIPGNDDASKAVALYTAGVADAIVEGRANAVNEVVQAARGGDGDEFVEVNSEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: IKIP_BOVIN
Sequence: MSEVKSRKKSGTKGAPAEPGKRNEGGKSPEARGGGGRGWADPRTGVSLLSLGTCLGLAWFVFQQSEKFAKVENQYQLLKMETSEFQGLQSKISLISEKCQKSEAIIEQLKAFQIITHLKHLQEEIYEVKTWSSRISEKQDILNNNLTTVSQDVAKADQSTTSMAKDIGLKITTIKTDIRRMSGLVTDVTSLTDSVQELENKIEKVEKNTVKNIGDLLSSSIDRTAMLRKTASENSQRINSVKKILSELQGDFNKHTDRLLSLESDRAKVLKTVTFANDLKPKVYNLKKDFSRLEPLVNDLTLRIGRLVTDLQQREKEIAFLKEKISNLTTVRAEIKDMKDEIKHISDMD
What is the function of this protein?
Target of p53/TP53 with pro-apoptotic function.
What are the official names of this protein?
Inhibitor of nuclear factor kappa-B kinase-interacting protein, I kappa-B kinase-interacting protein, IKBKB-interacting protein, IKK-interacting protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: RL1_ECO55
Sequence: MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLADQIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTMGAGVAVDQAGLSASVN
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: HIR1_SCHPO
Sequence: MKIKKIPWLGHFDDRGHRLSIFSIHIHPDGSRIATGGLDGTIRIWSTEAINRENENENENEDLPKQLCCMSTHTGTVTSVRFSPNGQYLASGSDDRVVIIWHKEEAIPGLGSTFGSGEKHTENWRSYRRLLGHDNDIQDLCWSYDSQLVVSVGLDSSIIVWNGTTFERLKRIEAHQSHVKGITFDPAGKYFATESDDRTIKVWRVSDFSIEKTITGPFNNSPLSTYFRRPSWSPDGKHIAAPNAMNGPVSCVSIIERGTWTSEINLIGHEGPVEVTAFNPKLFRDKNDKLVCILACGGQDRSLSIWSSALPRPLLSCQNVFQKSIGDVCWSPDGLSLFLCSYDGNVLVCTFEKEEFGDMVSDEEISKALAKYGHGRHGIVLPESAKQLELEETAYAILKKPSSLSTTDPTLVPQSSSTPKSAQKTPQKLPAFLPNRLTAETVDTNKLTASKEQIASPKRPGPSDNGNEIPTKFVQKVTITKEGKKRVAPQLLTTLSATPSTSRLASTQLQHTGSSQLPPQQFSQPINSLPKGGVPILIVGNKTKVNHENDESDQALQEEKIEEGLLKNYYSSLIDSSTSISNINFEAPRYKTNIVHSLNNEQKYVLEVKNGTSEKNPTRIVALENGNTKWMDYLPRPVILVTGSIHFWSIACDDGSLHLYSLTGSRLLPPIMIESKASFLHCNNAYLLCISSSGMVYAWNVVNKTALFTANSLAPILSRVSNNVTIENNSTDIPHVVIASISKEGVPSVTLSTGETYVYSSTMLCWQRITEPWWAIGSREWDSSGLLQSNTQTESQPLKIYEHRTNNVLMDSGRGKLLQKMVADAITEEGYDDFETIVTINHLENKIASARLLKLDDEFLVTSEVYVRLLMHHGLWQKLEEFLGELRTQTKCSIKLSGREVVAKMLVVLRQAVQTDNEFDRANKLIEKYAST
What is the function of this protein?
Probably required for replication-independent chromatin assembly.  Required for transcriptional silencing in the outer repeat (otr) centromeric repeats and the Tf2 long terminal repeat retrotransposons.  Repressor of histone gene transcription in G1 arrested cells.  Required for repression of htb1 gene expression outside of S phase.
What are the official names of this protein?
Protein hir1, Histone transcription regulator 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat HIR1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.