PharMolix/UniProtQA huggingface dataset:
Protein: ECT2_MOUSE
Sequence: MADDSVLPSPSEITSLADSSVFDSKVAEMSKENLCLASTSNVDEEMPQVEARVIMVQDAGKQEELLKALKTIKIMEVPVIKIKESCPGKSEEKLIKSIINMEMKVPCVKMDSMEEFESLDSPEFENIFVVTDFQNSVFNDLYKADCRIVGPPVILNCAQRGEPLPFSCRPLYCTSMLNLVLCFTGFRKKEELVKLVTLVHHMGGVIRKECNSKVTHLVANCTQGEKFRVAVSLGTPIMKPEWIYKAWERRNEQCFCAAVDDFRNEFKVPPFQDCILSFLGFSDEEKHSMEEMTEMQGGSYLPVGDERCTHLIVEENTVKDLPFEPSKKLFVVKQEWFWGSIQMDARAGETMYLYEKANTPELKKSVSLLSLSTPNSNRKRRRLKETLAQLSRETDLSPFPPRKRPSAEHSLSIGSLLDISNTPESSIHYGETPKSCAKSSRSSTPVPPKQSARWQVAKELYQTESNYVNILATIIQLFQVPLEEEGQRGGPILAPEEIKTIFGSIPDIFDVHMKIKDDLEDLIANWDESRSIGDIFLKYAKDLVKTYPPFVNFFEMSKEMIIKCEKQKPRFHAFLKINQAKPECGRQSLVELLIRPVQRLPSVALLLNDLKKHTADENPDKSTLEKAIGSLKEVMTHINEDKRKTEAQKQIFDVVYEVDGCPANLLSSHRSLVQRVETVSLGEHPCDRGEQVTLFLFNDCLEIARKRHKVIGTFRSPHDRTRPPASLKHIHLMPLSQIKKVLDIRETEDCHNAFALLVRPPTEQANVLLSFQMTSEELPKESWLKMLCRHVANTICKADAENLMYVADPESFEVNTKDMDSTLSRASRAIKKTSKKVTRAFSFSKTPKRALRMALSSSHSSEGRSPPSSGKLAVSRLSSTSSLAGIPSPSLVSLPSFFERRSHTLSRSTTHLI
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) that catalyzes the exchange of GDP for GTP.  Promotes guanine nucleotide exchange on the Rho family members of small GTPases, like RHOA, RHOC, RAC1 and CDC42.  Required for signal transduction pathways involved in the regulation of cytokinesis.  Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis.  Regulates the translocation of RHOA from the central spindle to the equatorial region.  Plays a role in the control of mitotic spindle assembly; regulates the activation of CDC42 in metaphase for the process of spindle fibers attachment to kinetochores before chromosome congression.  Involved in the regulation of epithelial cell polarity; participates in the formation of epithelial tight junctions in a polarity complex PARD3-PARD6-protein kinase PRKCQ-dependent manner.  Plays a role in the regulation of neurite outgrowth.  Inhibits phenobarbital (PB)-induced NR1I3 nuclear translocation.  Stimulates the activity of RAC1 through its association with the oncogenic PARD6A-PRKCI complex in cancer cells, thereby acting to coordinately drive tumor cell proliferation and invasion.  Also stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death.
What are the official names of this protein?
Protein ECT2, Epithelial cell-transforming sequence 2 oncogene.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cell junction. Cell junction, tight junction. Note=Sequestered within the nucleus during interphase. Dispersed throughout the cytoplasm upon breakdown of the nuclear envelope during mitosis. Colocalizes with the centralspindlin complex to the mitotic spindles during anaphase/metaphase, the cleavage furrow during telophase and at the midbody at the end of cytokinesis. Colocalized with RhoA at the midbody. Its subcellular localization to tight junction is increased by calcium. Localized predominantly in the cytoplasm of numerous carcinoma cells (By similarity).
Protein: FDHE_YERPY
Sequence: MSIRIVPKDQLGKQREKGTTAGNIPPLLFANLKSLYTRRTERLQQLALDNPLADYLDFAAKITEAQQKALHDHPLVLDMQAELVQSAASGKPPLDGSVFPRTEHWRKLLSALIAELRHDAPDHILAVLDNLDKASVHELELYADALLNRDFSQVGSEKAPFIWAALSLYWAQMASQIPGKARAEYGEHRQFCPVCGSIPVSSVVHIGTHNGLRYLHCNLCESEWHVVRIKCSNCEQTRDLNYWSLDSELAAVKAESCGDCGTYLKILYQEKDPQVEAVADDLASLILDAKMEGEGFARSSINPFLFPGE
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGE_SALA4
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIVNKPLENLQIEGILEKLKITPEPRDSSIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDNTVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKTPIAERWREAAKLIGIDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: PUR7_SALNS
Sequence: MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNHFIMTKLAEAGIPTQMERLLSDTECLVKKLEMVPVECVVRNRAAGSLVKRLGVEEGMELNPPIFDLFLKNDALHDPMVNSSYCETFGWVSQENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLDKMDKDRFRQSLGGLIEAYEAVAHRLGVKLD
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: CRY1_AEDAE
Sequence: MTVNNILWFRHGLRLHDNPSLLEALRNDGTGSESVRLYPIFIFDGESAGTKLVGFNRMKFLLESLADLDRQLREIGGQLYVFKGNAVNVMRRLFEELNIRKLCFEQDCEPIWKARDDAIQNLCRMMDVKCVEKVSHTLWDPQQIIRTNGGIPPLTYQMFLHTVDIIGKPPRPVAAPSFEFVEFGSIPSILAQEVKLQQVRNLSPEDFGIYYEGNPDISHQQWMGGETKALECLGHRLKQEEEAFLGGYFLPTQAKPEFLVPPTSMSAALRFGCLSVRMFYWCVHDLYEKVQANNQYRNPGGQHITGQLIWREYFYTMSVHNPHYAEMEANPICLNIPWYEPKDDSLDRWKEGRTGFPMIDAAMRQLLAEGWLHHILRNITATFLTRGALWISWEAGVQHFLKYLLDADWSVCAGNWMWVSSSAFEKLLDSSSCTSPIALARRLDPKGEYVRRYLPELKNLPTLYVHEPWKAPLDVQKECGCIVGRDYPAPMIDLAAASRANANTMNSIRQKLMERGGSTPPHCRPSDVEEIRNFFWLPEDVVADC
What is the function of this protein?
Blue light-dependent regulator that is the input of the circadian feedback loop.  Has no photolyase activity for cyclobutane pyrimidine dimers or 6-4 photoproducts.  Regulation of expression by light suggests a role in photoreception for locomotor activity rhythms.  Functions, together with per, as a transcriptional repressor required for the oscillation of peripheral circadian clocks and for the correct specification of clock cells.  Genes directly activated by the transcription factors Clock (Clk) and cycle (cyc) are repressed by cry (By similarity).
What are the official names of this protein?
Cryptochrome-1.
What is the protein family that this protein belongs to?
Belongs to the DNA photolyase class-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Note=Nuclear translocation initiates after the perception of a light signal.
Protein: LEU1_HAEIN
Sequence: MTDRVIIFDTTLRDGEQALKASLTVKEKLQIALALERLGVDVMEVGFPVSSQGDFESVQTIARHIKNARVAALSRAVDKDIDAAYEALKVAEAFRIHTFIASSALHVEAKLKRSFDDVVGMAVAAVKRARNYTDDVEFSCEDAGRTGIDNICRIVEAAINAGATTVNIPDTVGFCLPNEYGNIIAQVRNCVPNIDKAVISVHCHNDLGMATANSLTAVQNGARQIECTINGIGERAGNTSLEEVVMAMKVRQDFMGVDTHINTQEIHRVSQMVSQLCNMPIQPNKAIVGSNAFAHSSGIHQDGMLKNKNTYEILSPETIGLKKEKLNLTARSGRAAVKGHMADMGYNEQDYDLDKLYDEFLKLADKKGQVFDYDLEALAFIDMQQGDEDRLVLDKLSAHSTKEYPATAFVQLKLDGEKLSTSSIGGNGPVDAVYNAILNLTGLEIKMSHYNLTAKGEGAEALGQVDIVVEHKGRKFHGVGLATDIVESSALALVHAINAIYRAHKVADIKNHKHH
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: PYG_DROME
Sequence: MSKPQSDADRRKQISVRGIAEVGNVTEVKKNFNRHLHYTLVKDRNVSTLRDYYFALANTVKDNMVGRWIRTQQHYYEKDPKRVYYLSLEYYMGRSLTNTMINLGIQSECEEAMYQLGLDIENLEEMEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEYGIFAQKIKNGEQVEEPDDWLRYGNPWEKARPEFMLPVNFYGRVIDTPEGKKWVDTQRVFAMPYDNPIPGYNNNHVNTLRLWSAKSPIDFNLKFFNDGDYIQAVLDRNLAENISRVLYPNDNFFEGKELRLKQEYFMCAATLQDIIRRYKASKFGSREAVRNTFDHFPDKVAIQLNDTHPSLAIPELMRILVDEEHLTWEKAWDITVRSCAYTNHTVLPEALERWPVSLLESILPRHLQIIYHINFLHMENVKKKFPDDLDRMRRMSMVEEDGEKRINMAHLSIVGSHAVNGVAAIHSQILKDSLFHDFYEMEPQKFQNKTNGITPRRWLLLCNPGLSDLIAEKIGDEWPVHLDQLVALKKWAKDPNFQRNVARVKQENKLKLAAILEKDYGVKINPSSMFDIQVKRIHEYKRQLLNCLHIITLYNRIKKDPTANFTPRTIMIGGKAAPGYYVAKQIIKLICAVGNVVNNDPIVGDKLKVIFLENYRVTLAEKIMPAADLSEQISTAGTEASGTGNMKFQLNGALTIGTLDGANVEMAEEMGLDNIFIFGMTVDEVEALKKKGYNAYDYYNANPEVKQVIDQIQGGFFSPGNPNEFKNIADILLKYDHYYLLADYDAYIKAQDLVSKTYQNQAKWLEMSINNIASSGKFSSDRTIAEYAREIWGVEPTWEKLPAPEDQPQN
What is the function of this protein?
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism.  Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates.  However, all known phosphorylases share catalytic and structural properties (By similarity).  Required for glycogen breakdown in skeletal muscle.
What are the official names of this protein?
Glycogen phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the glycogen phosphorylase family.
Protein: HBB_CANLA
Sequence: VHLTAEEKSLVSGLWGKVNVDEVGGEALGRLLIVYPWTQRFFDSFGDLSTPDAVMSNAKVKAHGKKVLNSFSDGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LEU3_BLOPB
Sequence: MNNNYHIAVLPGDGIGPETTRQVYKILNVIKKQFQINIVTTEHKIGGDAINSEGTPFPKSTLKYCEQSNAILFGAVGGPQWTHLKGSESPEQGALLALRKHFNLFANLRPIYLADELKELSPLNINMIPNGIDIIFVRELTGGIYFGQPKGRSGTGLNEYAFDTAVYHRFEIERIANIAFKLAQKRRKRVSSIDKANVLHTSMLWREVVSHLAKNYPDVELEHLYIDNASMQLINNPSKFDIILCPNLFGDILSDECAMISGSIGMLPSASINEHNFGLYEPAGGSAPDIAEKNIANPIAHILSIALLFRYSLKLDHIAIKIEKAVSQALMLGYRTIDIAKKHEKSISTNEMGDIIAALIKNEREK
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS21_LEPIC
Sequence: MVGIIVKDGESIESALKRFKRDCANAGIMSEIKRREYFEKPSIKKKKAIESAKRKAEKKKRLFSKKDKA
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: EFG_XYLFT
Sequence: MVRATPIHRYRNIGIMAHIDAGKTTTSERILFYAGVCHQMGEVHDGAAVMDWMEQEQERGITITSAATTVFWSGMDKSMPQHRFNIIDTPGHVDFTIEVERSLRVLDGAVFVLCAVGGVQPQSETVWRQANKYFVPRMAFVNKMDRTGANFDKVVEQLKARLGAYPVPMQVPIGAEDGFEGVIDLLKMKAIHWDAASQGTVFEYRDIPIELVDKASKARAFMVEAAAEATEELMDKYLNEGELKEQEILEGLRERTLKVEIIPVFCGSAFKNKGVQAMLDGVIHLLPSPADRPPVQGLDEKGNECRCKASDSEPFSALAFKIMTDPFVGSLTFFRVYSGVLNSGDQVYNSVKLKKERVGRILQMHSNQRDEIKEVRAGDIAAAVGLKDVTTGDTLCDQNHIITLERMIFPEPVISMAVEPKTKSDQEKMGMALGRLAQEDPSFRVKTDEESGQTIISGMGELHLDIIVDRMRREFNVEANVGKPQVAYRETIRKSDVKSDYKHVKQSGGKGQYGHVVIEISPMSDVDKQHPDVKGDFLFINEITGGVIPKEFISPIEKGLRETITSGPLAGFPVVGVKVKLVFGSYHDVDSSEMAFKLAASMAFKQGFAKANPVLLEPIMKVEIVSPEDYLGDIMGDVSRRRGVLQGQDDSLSGKVINAMIPLGEMFGYATSLRSMTQGRATFAMEFDHYEEAPTNIADTVIKKT
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFMT2_HUMAN
Sequence: MSSGADGGGGAAVAARSDKGSPGEDGFVPSALGTREHWDAVYERELQTFREYGDTGEIWFGEESMNRLIRWMQKHKIPLDASVLDIGTGNGVFLVELAKFGFSNITGIDYSPSAIQLSGSIIEKEGLSNIKLKVEDFLNLSTQLSGFHICIDKGTFDAISLNPDNAIEKRKQYVKSLSRVLKVKGFFLITSCNWTKEELLNEFSEGWSTVAGFWLTAALTSWAQAIFSTSASRVGGTTGTHHHAWIIFVFLAETRFCHVVQAGLELLGSSDSPTWPPKVLGLYHARPSLAF
What is the function of this protein?
Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.
What are the official names of this protein?
EEF1A lysine methyltransferase 2, Methyltransferase-like protein 10, Protein-lysine N-methyltransferase METTL10.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
Protein: WEE1A_XENLA
Sequence: MSLQPVPHRLLFSDSDDEEDGHSTGEDSAFQESDSPVSRLREKQEGPGGSWEEEEGLGSSPIKSPGHFFMCDSPTYRDLPPASPPGPAASPPDCPGTPPHKTFRKLRLFDTPHTPKSLLSKARGIGSSALRFRGGTLFREAEKLPKPEFTYSTPQVNINPFTPDSLEIQSSTGLCRRRKRALLNDSCGEDMEGSDCELEDEDVRPAKRIPITESNMKSRYATEFHELEKIGSGEFGSVFKCVKRLDGCIYAIKRSKKPMAGSVDEQNALREVYAHAVLGQHPHVVRYYSAWAEDDHMLIQNEYCNGGSLADAISENYRTMQYFTEPELKDLLLQVARGLKYIHSMSLVHMDIKPSNIFISRITVPNTGVEEGDDEDCGSGNVVYKIGDLGHVTRVSSPQVEEGDSRFLANEVLQEDYTHLAKADIFALALTVWCAAGAEPFPTNGDQWHEIRQGKLPRVPQLLSQEFVDLIKLMISPDSEKRPSSMALVKHSVLLSASRKNAEQLRIELNAEKFKNALLQKELKKAQIAKAAAEERALFPDRIATRSTTQSNRTTRLIGKKMNRSVSLTIY
What is the function of this protein?
Acts as a zygotic negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed cdk1 before the onset of mitosis by mediating phosphorylation of cdk1 on 'Tyr-15'.  Specifically phosphorylates and inactivates cyclin B1-complexed cdk1 reaching a maximum during G2 phase and a minimum as cells enter M phase.  Phosphorylation of cyclin B1-cdk1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric cdk1 does not occur.  Involved in convergent extension of the paraxial mesoderm during neurulation by inhibiting the cell cycle.
What are the official names of this protein?
Wee1-like protein kinase 1-A, Zygotic wee1-like protein kinase 2, XWee2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADK_RUMCH
Sequence: MKKIGVITNREKDKGLKYTNQLVESIEKHGGQAVLPTYDGSFQMDDIDNQVVEICNNCDMVICLGGDGTFLRTARTAYLYGLPMLGINLGSLGFLTDVEKGEIDKAVENILNNRFCLEDRIMLTSKLYKDGKLIARDVAINDIVISRGGIPRILHLSTYIDNNLVEMFPGDGIVVATPTGSTAYSLSAGGPIVEPTSGLILITPICPHILSSRALITSDMRKIKICVSQGFEHKATVTVDGQKNLEITGGDYLEIEKANSTVKIIRVNSKNFFTVLRSKIYERKEE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_HAEIE
Sequence: MAAKGAREKIRLVSTAETGHFYTTDKNKRNMPEKMEIKKFDPVVRKHVIYKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SYFA_PSEA6
Sequence: MDLDAIIKEAETQINVAQDASTLDAVRVDFMGKKGRMTELLKGLGKLSNEERPAAGQKINQAKQQIQQLIHQRGELLREQEMNSKLAAESIDVSLPGRTTEMGGLHPVTRTINRIESFFAELGFSVKTGPEIEDGFHNFDALNIPANHPARADHDTFYFNPDVMLRTQTSGVQIRTMEAEQPPLRIISPGRVYRNDYDQTHTPMFHQVEGLMVDKNVSFTQLKGILHDFLNNFFEADLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRAVNIDPEVYTGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3NOJ6_DENJA
Sequence: LECYRCGVSGCHLRTTCSAKEKFCAKQHNRISTLWWHGCVETCTEDETWKFYRKCCTTNLCNI
What is the function of this protein?
May enhance presynaptic acetylcholine release.
What are the official names of this protein?
Toxin S6C6.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Orphan group XIX sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CX8_CONCB
Sequence: MKLFMFAAIIFTMASTTVRAEQCANNRKVCTWDGQGDTNCDCIGTACHEDDAHKVSVAGSAFYTCQPISAFRVCDGSEDVMDAGFSELYCRCSGGSYTISNGEVVCD
What is the function of this protein?
Acts as a neurotoxin.
What are the official names of this protein?
Putative conotoxin.
What are the subcellular locations of this protein?
Secreted.
Protein: HSDL2_BOVIN
Sequence: MLPNTGKLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQAHPKLPGTIYTAAEEIKAAGGKALPCIVDVRDEEQISSAVEKAVEKFGGIDILVNNASAISLTNTLETPTKKVDLMMNVNTRGTYLTSKACIPYLKKSKVAHILNLSPPLNLNPLWFKQHCAYTIAKYGMSMCVLGMAEEFKGEIAVNALWPRTAIHTAAMDMLGGSGVESQCRKVDIMADAAYCIFKKPKSFTGNFIIDENILKEEGIKNFDVYAITPGHPLLPDFFLDEQPAMVTKKADSYGAVPELKEEKTQPPPKARSGAVEETFRIVKDSLSDDIVKATQAVYQFELSGEDGGTWFLDLKSKGGNIGYGEPSDQADVVMSMSTDDFVKMFSGKLKPTMAFMSGKLKIKGNMALAIKLEKLMNQMNSKL
What is the function of this protein?
Has apparently no steroid dehydrogenase activity.
What are the official names of this protein?
Hydroxysteroid dehydrogenase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: CO1A2_LITCT
Sequence: MLSFVDLRSVLLLAVTLYLVTCQEVRRGPRGDKGPPGEQGPPGIPGRDGEDGLPGLPGPPGVPGLGGNFAAQYDPSKSAEPGQQGIMGPRGPPGPPGSPGSQGFQGLPGENGEPGQTGPVGSRGPSGAPGKAGEDGHPGKSGRPGERGPVGPQGARGFPGTPGLPGFKGIRGHTGSDGQKGAPGAAGVKGENGANGDNGSPGQAGARGLPGERGRIGPAGSAGSRGSDGSSGPVGPAGPIGSAGAPGLPGAPGAKGELGPAGNNGPTGAAGGRGEPGPPGSLGPAGPPGNPGTNGVNGAKGTAGLPGVGGAPGLPGGRGIPGPAGPAGPSGARGLAGDPGIAGGKGDTGSKGEPGSVGQQGPAGPSGEEGKRGPNGEAGSSGPSGNAGIRGVPGTRGLPGPDGRAGGIGPAGSRGSSGPPGARGPNGDAGRPGEPGLLGARGLPGFSGSNGPQGKEGPAGPQGIEGRSGAAGPAGARGEPGAIGFPGPKGPNGEPGKNGDKGNQGPSGNRGAPGPDGNNGAQGPAGLGGATGEKGEQGPSGAPGFQGLPGPGGPPGEVGKPGERGAPGDFGPPGSAGTRGERGAPGESGGAGPHGPSGSRGPSGAPGPDGQKGEPGAAGLNGGLGPSGPAGIPGERGTAGTPGTKGEKGDAGNSGDYGNPGRDGARGPAGAAGAPGPAGGPGDRGESGPAGPSGVAGPRGAPGERGEAGPAGPTGFAGPPGAAGHTGAKGDRGAKGPKGEAGSPGPLGAHGSAGPAGPNGPAGSTGARGDAGPSGATGFPGPAGRAGAPGPPGNVGPSGPTGHPGKDGSRGPRGDSGPVGRPGEQGQHGPVGLAGDKGPSGEAGPAGPPGAAGPSGVLGARGILGLPGTRGERGLPGGPGSNGEPGPSGLAGSSGPRGPPGSVGSPGPVGHSGEAGRDGHPGNDGPPGRDGLPGAKGERGYPGNTGPSGLAGAPGPAGSAGPAGKSGNRGEGGPSGPAGITGPSGPRGPAGPQGVRGDKGEAGERGARGLDGRKGHNGLSGLPGPSGTPGETGPSGSVGPVGPRGPSGPSGPPGKEGRSGHPGAMGPVGPRGPAGFTGPAGPPGPPGPPGHAGPSGGGYDGGDGGEYYRADQPERKPKDYEVDATLKSLNQQIEVILTPEGSRKNPARTCRDLRLSHPEWTSGFYWIDPNQGCTSDAIRVFCDFSSGETCIHANPDEITQKNWYINTSNKDKKHLWFGEILNGGTQFEYHDEGLTAKDMATQLAFMRLLANQASQNITYHCKNSIAYMDEETGNLKKAVILQGSNDVELRAEGNTRFTYSVLEDGCTKHTGEWGKTVIEYRTNKPSRLPILDIAPLDIGGHDQEIGFEIGPVCFK
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-2(I) chain, Alpha-2 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CAS1B_CHLTE
Sequence: MKSNTLGDEGNPARLLIKVTRETLPQVKEKYPFLYLEKGRIEIDDSSIKWIDCDCNVVRLPVAMLNCILLGPGTTVTHEAVKVMAAANCGICWVGDDSLMFYASGQTPTSNTRNMTHQMKLAANPAKALEVARRLFAYRFPDANLENKTLPQMMGMEGLRVRKLYEEMAVKYKVGWKGRRFEPGKFEMSDTTNKILTASNAALYSIILSAVHSMGYSPHIGFIHSGSPLPFIYDLADLYKQQVSIDLAFSLTADMAGYYDRHKIASEFRKRVIEIDLLGKIGPDIETILGKKQCSS
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.
What are the official names of this protein?
CRISPR-associated endonuclease Cas1 2.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: Y1252_STAAC
Sequence: MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein SACOL1252.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: DNJB7_MOUSE
Sequence: MVDYYEVLGVQRYASPEDIKRAYRKVALKWHPDKNPENKEEAERKFKEVAEAYEVLSNVEKRDIYDKYGKEGLDGRGASHLDDEREYRFTFRKADDVFKEIFGERDPFSFHLFEDSLEGLLNSSRSPSGSRGRGAGSHVSRAYDHPALSGLSSYDTGYSSYVSLGHEGLTSFSSLALDDSGMGNYIPITPSGKVINGRNINTKKAFENRQEREAEDDSELISFLVNSVANEEHFTDKCNWRRQSFNNYSPNSYSSSNTTQYTLVDNNEQGTSWVTNKKEPSIFSAGFKEGGRRKKKKHKEGQKKKKSNKRNH
What is the function of this protein?
Probably acts as a co-chaperone.
What are the official names of this protein?
DnaJ homolog subfamily B member 7, mDj5.
Protein: AMPA_BACAH
Sequence: MFQVQKELASHEAVVVALFEEEKTSSFVQELDKAFEGQLQVLLEEKELSTKKKAISKVHSLGKTDVKRYYFVGLGKKESYTTETLRSALGKTFKTLQAAKVQDAAILLDSFVTEKLDAIDVAHIAAEVQGLGTYELQTYKSDKKDRVKLEKFTAITAEDAQEIEAALTVGYVHGRATNSARTLVNMPPNVLTATKLAEYAVELAEKYDMDYKVLEKEEMEELGMGALLAVNQGSVEPPKMIALIYKGKEEWTDVIGFVGKGITYDTGGYSLKPREGMVGMKGDMGGAAAVLGAMEIIGELRPEQNVIAVIPSTDNVVSGTAFKPDDVITSMSGKTIEVLNTDAEGRLALADGITYAKKLGANYLIDVATLTGGVIVALGNHTTGAMTNNEELFEQVLEASMETDESIWQLPIFDRDKERVRNSKFADLNNSPGREGHAVMAGTFIGEFAEDTPWVHLDIAGTSESSGAHDLGPAGATGAMVRTLATLVERFGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_STRP2
Sequence: MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFEDNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKRIPVLTEVELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASDKDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAADFLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBEY_BURL3
Sequence: MTLHVGAEPAPREDDTEDALREPELDLSVQYGDEITSDVRKTLPKRKLIAEWIEPALFASAQLTVRFVGEEEGRTLNAGYRHKDYPTNVLTFAYDAAPDGTVIGDLVLCCPVVEKEAHEQGKPLTAHYAHLLVHGALHAQGYDHETSDEDAAEMEALEVDILAKLGFPNPYQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.