PharMolix/UniProtQA huggingface dataset:
Protein: RECF_HYDCU
Sequence: MSKILQFQLQHFRNIEQASLTFGEGLNLIVGDNAAGKTALIEAIWTLASGRSFRTAKPHQLIQQNQSELVLFGTLTEADRIHKIGLARTSDKVTLKIDGELAKTQADMSAKLPVQLLTPESHRLLEEGPKARRQFMDWGCFHHNADFIHLWRHYQRALKQRNHALKKRLPASQIQLWDAQLVDAAEKIDVIRADYITRLTPYLVEFCQALMPEITVSPECHYRPGWPKTAESYRQLLADNFAKDTLQGHTQYGSHRADIKFRFNGQEALMILSRGQQKLFVCALLLAQATLYQQHSQNPVIMLIDDLPAELDAKHRETLLKLLNLLDIQHILTSTAQDLIPVLEPEKAKIWRIQHGELIEQQ
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I02A4
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKSDYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEAKRQLKKDLKLQEPCAGLPTKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCQKR
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: RS18_THEMA
Sequence: MAYRRRKKKIKKCRLCEMKLDYVDYKDTRLLSEFLTDKGKIIPKRLTGNCSKHQRMVKVAIKRARQMGLLPYLKI
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: MACB_PSYCK
Sequence: MSSQDLYANAATDKPLMQVKGLIREFKAGEQTIRVLHDINLTIHQGEMVAIIGQSGSGKSTLMNILGCLDQATAGDYQVFGQSVNRLVPDELAKLRREHFGFIFQRYHLLGDISARDNVSVPAVYAGMDGQARNERAEKLLSDLGLADKVNNRPSQLSGGQQQRVSIARALMNGGDIILADEPTGALDSKSGKDVVQILKDLNAQGHTIIMVTHDPSLAAQAERVIEIKDGYIIADYKNEDYQRPAAQPASIIDKHRKSAFGSFIDRLLESFKMSLLAMRAHKMRTLLTMLGIIIGIASVVSVVGLGKGSQEQILSNISSLGTNTITVTDGYPYGDPRRQYNDDNLTPQDAQAVADQPYVLSVSPQLNSNMSVRYRNVQEAASISGVGKDYLDVSGETLAMGQGFDEQSILRRTQDIIIDSNAHKTFFPTIANPIGEVLLIGSVPGRVIGVLEPNEGGFSRSVDTPTLYMPYTTMMSRLIGSAYIESFIALIDNNISSSAAESAISDLMTSRHGTDDFRIRNSDSIRQTIESTTAALTLLISSIAIISLIVGGIGVMNIMLVSVTERTNEIGVRMAVGARQSDIMQQFLIEAILVCILGGLLGIGLAFAIGELINRVGGDSFKVIYSSTSIIAAFVCSTLIGVVFGFLPARNAAKLDPVEALSRD
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSTB2_STRR6
Sequence: MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFERNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKHIGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKSALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDFTIIIVTHNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB 2, ABC phosphate transporter 2, Phosphate-transporting ATPase 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YQO6_SCHPO
Sequence: MKLFPLCLSALVMSTATCASSVEGAIEKVPQSLEQKGPSEMLSMKPDVKGGFGDRMMFIPFQSDLGLHSPVDRSGFEYCGYLDAIESEDGDSSRAPYAKLQLKENVEGIARFGLFYHPSPFQAFKHIIDNGGKYSGLDRVFLENLRKSLVVSLDSAVNRTYSIPVEDEGFYCFVGYQEVAHQETVIGENSEPIVTIEFDSFNSNVPVTLKLQRQIFLSFSIVYGLISLWWAIRCICSRTKLHLVQVCLFCWFSFFILNHPVKQRIFSIDNPDEYLVPFVVSCFTYFLGDGIEYALYSLFITTTVLGFGTIRRTSKKMVLFFSLLTCGQAFLVNVAPMVYPLLYISGSDKACVLRMVWVFNKFLYLPLITFLGAVLAFRFRLKKASQFDTRWNLFALTLAIIILFAFNDLVIFDKLQKLWKYDDTTLEYLKIVNGGIKFVAFSILLGPYSKLFAEPKSLQLDDFLGKHDGHKDPSLEKF
What are the official names of this protein?
Uncharacterized membrane protein C569.06.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RS11_THEPX
Sequence: MAKRVKRAGRKREKKHVERGIAHIHSTFNNTIVTITDPAGNTISWASAGTIGFKGSRKSTPFAAQMAAESAAKSAMEHGMKTVDVYVKGPGAGREAAIRALQAAGLEVSLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SDRE_STAAS
Sequence: MINRDNKKAITKKGMISNRLNKFSIRKYTVGTASILVGTTLIFGLGNQEAKAAENTSTENAKQDDATTSDNKEVVSEAENNSTTENDSTNPIKKETNTDSQPEAKEESTKSSTQQQQNNVTATTETKPQNIEKENVKPSTDKTATEDTSVILEEKKAPNNTNNDVTTKPSTSEIQTKPTTPQESTNIENSQPQPTPSKVDNQVTDATNPKEPVNVSKEELKNNPEKLKELVRNDSNTDHSTKPVATAPTSVAPKRVNAKMRFAVAQPAAVASNNVNDLIKVTKQTIKVGDGKDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTINYDKNVIPSDLTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKYEDIKSRLTLYSYIDKKTVPNETSLNLTFATAGKETSQNVTVDYQDPMVHGDSNIQSIFTKLDEDKQTIEQQIYVNPLKKSATNTKVDIAGSQVDDYGNIKLGNGSTIIDQNTEIKVYKVNSDQQLPQSNRIYDFSQYEDVTSQFDNKKSFSNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDKYGYYNYAGYSNFIVTSNDSGGGDGTVKPEEKLYKIGDYVWEDVDKDGVQGTDSKEKPMANVLVTLTYPDGTTKSVRTDAKGHYEFGGLKDGETYTVKFETPTGYLPTKVNGTTDGEKDSNGSSVTVKINGKDDMSLDTGFYKEPKYNLGDYVWEDTNKDGIQDANEPGIKDVKVTLKDSTGKVIGTTTTDASGKYKFTDLDNGNYTVEFETPAGYTPTVKNTTAEDKDSNGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKDVTVTLQNEKGEVIGTTKTDENGKYRFDNLDSGKYKVIFEKPAGLTQTVTNTTEDDKDADGGEVDVTITDHDDFTLDNGYFEEDTSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGKHTPVKPMSTTKDHHNKAKALPETGSENNGSNNATLFGGLFAALGSLLLFGRRKKQNK
What is the function of this protein?
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis.  Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity.  Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation.
What are the official names of this protein?
Serine-aspartate repeat-containing protein E.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A (By similarity).
Protein: RL15_CHICK
Sequence: PRPTRPDKARRLGYKAKQGYVIYRVRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKRIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15, L10.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FL3H_PETHY
Sequence: IPRVTPSTLTALAEEKTLQTSFIRDEDERPKVAYNQFSNEIPIISLEGIDDETGKRAEICDKIVKACEDWGVFQVVDHGVDAEVISQMTTFAKEFFALPPEEKLRFDMSGGKKGGFIVSSHLQGEVVQDWREIVTYFSYPTRARDYSRWPDKPEGWIAVTQKYSEKLMELACKLLDVLSEAMGLEKEALTKACVDMDQKVVVNFYPKCPEPDLTLGLKRHTDPGTITLLLQDQVGGLQATKDNGKTWITVQPVEGAFVVNLGDHGHFLSNGRFKNADHQAVVNSNSSRLSIATFQNPAPEAIVYPLKIREGEKSIMDEPITFAEMYRRKMSKDLELARLKKQAKEQQLQAEVAAEKAKLESKPIEEILA
What is the function of this protein?
Catalyzes the 3-beta-hydroxylation of 2S-flavanones to 2R,3R-dihydroflavonols which are intermediates in the biosynthesis of flavonols, anthocyanidins, catechins and proanthocyanidins in plants.
What are the official names of this protein?
Naringenin,2-oxoglutarate 3-dioxygenase, FHT, Flavanone-3-hydroxylase, F3H.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: PDAB_BACSU
Sequence: MNHFYVWHIKRVKQLIIILIAAFAAASFFYIQRAVPLPVFSTDTGPKAIYKGETDSKDISLTFDISWGDERAEPILNTLKANGIKNATFFLSASWAERHPDTVARIVKDGHQIGSMGYAYKNYANLESSEIKKDMNRAQTAFEKLGVKDIQLLRPPTGQFNKNVLKVAKQYNYTVVHYSVNSQDWTNPGVEKIIDNVTKQVSGGDIILLHASDSAKQTEEALPDIIHQLKEKGLKNVTVGDLIANSDAKSAEVK
What is the function of this protein?
Necessary to maintain spores after the late stage of sporulation.  Might be involved in cortex formation.
What are the official names of this protein?
Probable polysaccharide deacetylase PdaB.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
What are the subcellular locations of this protein?
Forespore. Note=Produced in the mother cell compartment and transported into the forespore.
Protein: YVAV_BACSU
Sequence: MEKDPLTIIEQAEDHFIERIAENMHAFGMPSTVGRVLGIIYMNRKPMTLTELSEATGMSKTRMSQVVREMLDANIAEKVFEKGVRKDLYEVEQDYYQTFITLFSATWSKVVSKNKMMHKKLNRELLSVLDEELTPEAEEKVNELLKELKEWLDYYNWLSRLIEFFESEDIFKYVPKP
What are the official names of this protein?
Putative HTH-type transcriptional regulator YvaV.
What is the protein family that this protein belongs to?
Belongs to the GbsR family.
Protein: IF1_BORGP
Sequence: MNIKEEAIETEGIVKESLPNTMFRVELKNKHIVLAHLSGKMRKHFIKIVPGDKVKVELSPYDLTKGRIVYREK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_PSEPF
Sequence: MKFSEQWLRGWVSPQVDRDALVARLSMAGLEVDSVTPAAGVFSGVVVGEVLSTEQHPDADKLRVCQVSNGAETFQVVCGAPNVRPGLKIPFAMIGAELPGDFKIKKAKLRGVESNGMLCSQAELQIGEGNDGLMELPADASVGEDFRVYLDLEDASIEVDLTPNRGDCLSLAGLAREVGALYDAPVTRPVVMAVPAAHDEVRSVEVLAPAACPRYLGRVIRNVDLSRPTPLWMVERLRRAEVRSIDAAVDITNYVMLELGQPLHAFDLAEINGGIRVRMAEEGEKLVLLDGQEVSLRSDTLVVADHTRALAIAGVMGGEHSGVSATTRDVFLESAFFDQIAVAGKARSYGLHTDASHRYERGVDWQLAREAMERATGLLLEITGGEAGPIIETVSEQHLPSIAPITLRAQRITQMLGMEMDSAEVERLLNALGLKVSADGAGQWRVEVPSHRFDISLEVDLIEELARLYGYNRLPVRYPQARLAPQAKAEARSDLPELRRLLVARGYQEAITYSFIDPKQFELFNPGVEPLLLANPISNDMAAMRSSLWPGLVKALQHNLNRQQDRVRLFESGLRFVGQLEGLKQEPMIAGVVCGSRLPEGWAQGRDTVDFFDVKADVEAVLGFAGALDQFTFAPGKHPALHPGQTARIEREGREVGFIGAIHPELSKSLGLDRPVFVFELVLAEVALGKMPKFHELSRFPEVRRDLALIAHKDVAASAVLDVIRENAGEWLTDLRLFDVYQGKGIDTDRKSLAVGLTWQHPSRTLNDDEVNSTTQNILTSLEQRLNATLRK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y987_CAMJE
Sequence: MEKSLLFHFRRIGVEFIIFSVYAVFSISWAATGSLMPLISNDLALNTQQATLITSMIVVAKIFGASFTAFLVYKFGLKKGYFLGCILMSSGIFLSFVDSYSGILIIRFLTGLGSACALVCLVPIAQQWFEKKALHFVISFNITSNLVGITLGLVLAESISNYFGNWRDSLSFYAWINLILLILWLFVGKDENKKEEKKNNAKDLIYALKSRVTWGMIIFYIGPILFLNSLFTFLPTFYAQYAGFSKELADFAKKEIPALANFAIIFGPYLGLFFKRKNISFKIMLLSGGACIFICGFCMLFLQNLVLIQIFAVLSGIFYSM
What are the official names of this protein?
Uncharacterized protein Cj0987c.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GLMM_GLUDA
Sequence: MSKTRHLFGTDGIRGLANQDPMTVEIAQKLGQAAGLRFTRGVHRHRVLLGKDTRLSGYMIECALVSGFLSAGMDVTLVGPMPTPAIAMLTRSLRADLGVMISASHNPFGDNGIKLFGPDGFKLSDETEAEIEELMRSDLAGRLAAPDRIGRASRLNDAAGRYIENAKASFPRGRRLDGLRIVIDCANGAAYRVAPTALWELGAEVIRIGCEPDGININEQCGSTKPESLCEAVVAHGAHIGIALDGDADRVLIADEKGRLIDGDQILALIARSWGRQGRLNSAQIVATVMSNMGLARCLEGLGLELVRTAVGDRYVVERMRELGANLGGEQSGHMVLSDFATTGDGLVAALQVLAVLVEEGRPASEVCRMFTPFPQMLRNVRFTGKSPLHAPSVQDARRRAEAELGTAGRLLLRESGTEPLVRVMAEAEDPALVERIVAEMCEAIDSAQVVA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: WDR55_AEDAE
Sequence: MRNFNSPKFGHSMGDDSDDDDFDSGTEPEFLVEPYVLEEFPITEEIEEIEGDDEEYNPNEEIGTSSSDDEDDSDDSDSDKEQENGGEDGEDSSTTNTVPKRVIDDYDEDMEEDEVIKAIITEIKKPRSKPPDIKTEDFVTDLCFHPDQDLLAVGTTTGDVIVYKFTNDECTIVNTHETHTKSVRDVEFNADGDLLISTARDRSIMVTDVETGKLKRFWDDAHEEPVYTMSMITEHTFATGDDGGVLKLWDLRQKDPVFKLKEVEDFISCIITNEQKKYLLMTSGDGYLTTINIPQRKMYVQSEPYEEELTCMGVFRRDSKLVVGSSKGNFYTFNWGQFGYHCDAFIGPKAGVNKMVPITERIAVTGGEDGILRAMHLVPGRVLGIVGQHSLAVETMDINSTGELIASSSHDNDIRFWNIKYFEEFDDIKYNSKPDKKAMTHNLPSSKQTNAADFFSGLAGDQSGAEGD
What are the official names of this protein?
WD repeat-containing protein 55 homolog.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
Protein: HTPG_HELHP
Sequence: MATKHQFQTEITQLLDLMIHSLYSHKEIFLRELISNASDALDKLSYLTLTQENLKTLSFEPRIDISFDEEKKTITIEDNGIGMNENDMKEHLGIIAKSGTKSFLSQLSGDKKKDSALIGQFGVGFYSAFMVAHRVVVQSKKAGEEKAYAWVSEGKGEYEIGECVKESQGTQITLYLREEDAHFASRWEIEGIIHKYSEHIAFPIYLAFVESKFEGEGENKKEIKENKQSQINTAKALWKIPKAELKDTDYKEFYATLSHDNNEPMRWIHTKVEGNLEYTTLFYIPQKAPFDLFRVDYQSGVKLYVKRVFITDDDKELLPPYLRFVRGVIDSEDLPLNVSREILQQNKILANIKSASTKKILSEITNIAKNEADYKTFYEQFGKVLKEGLYGDYENKEKILELLRFDSFKSEYISLKAYKESMGNEQKSIYYMLGENKDALKNAPLLEKFAQKGFDVLLLSDEIDAIVMPMVGEYDKVPLKSINSKEALAELGEESIDEATQNAYEPLIKGFKDALGEQIAEVKLSSLGDAPLTLIKEDNNPMMANLMAQMGQKVPETKPILQLNITHPLFEKLKTAQEDKIKQSALLLFGAALILEGSTLKNAKDFNTELNSLLLQSL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_CORGL
Sequence: MAKKKKKVDENNSVLATNRKARHDYHIIDTWEAGVVLLGTEIKSLREGKVSLVDSFATIDNGEIWLQHLHIPQYSMGSWTNHTPKRTRKLLLHRNEIDSLMGKVRDGNRTLVPLKLYLKNGRVKLELGLAQGKQDYDKRQDIKRRTEEREVTRELGRRIKGINA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: KHSE_CUPPJ
Sequence: MAVFTTVSHDEIASWLLDYDLGEVRELRGIASGIENSNFFLTTEQDGRTREYVLTIFERLTFDQLPYYLHLMAHLATRGITVPAPIPARDGEILRALKGKPATIVTRLPGASQLAPDAEHCAEVGDMLARMHLAGQDYPRQQPNLRSLPWWQQTEAEIVPFLDAQQRTLLQQEIAHQAAFFGSADYAALPGGPCHCDLFRDNALFEEVGGHHRLGGFFDFYFAGNDKWLFDLAVTVNDWCIDLASGELDNARAHAMVQAYHAVRPLSATEAAHWRDMLRAGALRFWVSRLWDFYLPREADMLQPHDPTHFERILRRRLAMTADAAALAWI
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: RL19_CHLTA
Sequence: MGNLIKELQDEQCRTDLADFCVGDTIRVATNISEGGKERVQVFQGTVMARKGGGAGETVSLHRVAYGEGMEKSFLLNSPKIVSIEVVKRGKVSRARLFYLRGKTGKAAKVKELIGSRAAKK
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: URM1_YEAST
Sequence: MVNVKVEFLGGLDAIFGKQRVHKIKMDKEDPVTVGDLIDHIVSTMINNPNDVSIFIEDDSIRPGIITLINDTDWELEGEKDYILEDGDIISFTSTLHGG
What is the function of this protein?
Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by UBA4.  The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1.  The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.  Indirectly involved in regulation of budding and haploid invasive growth.
What are the official names of this protein?
Ubiquitin-related modifier 1.
What is the protein family that this protein belongs to?
Belongs to the URM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MAP1_GEOSE
Sequence: MIICKTAHEITLMREAGKIVSATLEELKNHIRPGVTTKELDAIAEEVIRSH
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity).
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: MOT14_MOUSE
Sequence: MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKLENCPEAEEPCALPAYSTESVKSGGPLGMAEEQDRRPGNEEMVCDLQTQECQGQTHPRKNVCAFRVLKTVSQLTVQVRRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMIDQSRRKCIEGAHV
What is the function of this protein?
Proton-linked monocarboxylate transporter.  May catalyze the transport of monocarboxylates across the plasma membrane.
What are the official names of this protein?
Monocarboxylate transporter 14, MCT 14, Solute carrier family 16 member 14.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TAZL_ASPTN
Sequence: MRSNTVILAALPLVASAASTSGNWGGGVNYSKIFGGGLSANASIHYPGQPDYNTTTVQRWSTWAEPTFAVTIKPATDEDVQYIIRTANKYNLTFLATGGGHGGETGFATVKHAVNIDLSNFKENVLDLEANTLTVGPGNSFSAFETNLYNAGKMVPVGNAFCVNMIGATIGAGVGPYQGLHGLVIDALRSVRLVTASGDIVTASDEENPDLFWAVRGAGANFGIITSATYEIFDAPNNGNVVLAEFAYPGSVNGSLWQLLESWGETYPKEMGLTMSASYSQTTGTTSSSASLTYFGTQEAAQPWIDQLLALNPTQWRNATLPWSEVSQNSGFGTGASVCATGKYNNHPSVGAKQTSVSTYIEVFNQYVEIMKARPWLTSALVVQRFNTTATLAVPESKRGVYPGRDFSSLIILENYYDGPRHDADVYRFSKKLRSQLVATSGFDSLQTYINYAHGDEGPEVWYGKDNLPRLVQLKRQWDPEGKFGPGNPIPLA
What is the function of this protein?
FAD-linked oxidoreductase; part of the gene cluster that mediates the biosynthesis of azaterrilone A and other azaphilones, a class of fungal metabolites characterized by a highly oxygenated pyrano-quinone bicyclic core and exhibiting a broad range of bioactivities (PubMed:35398258).  The first step of the pathway begins with the non-reducing polyketide synthase tazA that assembles one acetyl-CoA starter unit, five malonyl-CoA units, and catalyzes a series of Claisen condensations, methylation, PT-mediated cyclization, and finally releases the first hexaketide precursor through the R-domain.  The tazA product then undergoes reduction on its terminal ketone and the following pyran-ring formation by yet undetermined enzyme(s).  Dehydration and enoyl reduction, possibly involving the trans-enoyl reductase tazE leads to the next intermediate.  TazD is predicted as an acetyltransferase and might catalyze the acetylation steps leading to the synthesis of azaterrilone A.  Azaterrilone A is not the final product of the taz pathway and both the highly reducing polyketide synthase tazB and the dual enzyme tazHJ catalyze late steps of the pathway, leading to the production of the 2 final stereoisomers that contain additional polyketide modification whose structures have still to be determined (Probable).
What are the official names of this protein?
FAD-linked oxidoreductase tazL, Azaphilone biosynthesis cluster protein L.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: CYBH_RHOCA
Sequence: MKGVSDERINAPVRGPDEIFEASRLTGDATREDLESIRRRTSVYVYEAPVRVWHWVNALAITILVVTGYFIASPLPSMQIGEATDQFVMGYIRFAHFAAGVVMSVAFFGRIYWAFVGNRHAWQMFYIPIFNKRYWKEFVFELRWYFFLEEEPKKYIGHNPLAHAAMFTFITLGITFMMITGWALYAEGAGQGGVTDSLFGWVLGYVQNSQRLHTLHHLGMWAIVIFAIIHIYAAVREDVMSRQSMVSTMISGHRTFKDDRIE
What is the function of this protein?
Probable b-type cytochrome.
What are the official names of this protein?
Probable Ni/Fe-hydrogenase B-type cytochrome subunit.
What is the protein family that this protein belongs to?
Belongs to the HupC/HyaC/HydC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UREG_RHIME
Sequence: MPSKNGPLRIGIGGPVGSGKTALTDKLCKAMREKYSVAVVTNDIYTKEDAEALVRMQALPSERIVGVETGGCPHTAIREDASINLQAIADLNRRIPDLDVVFIESGGDNLAATFSPDLADLTIYVISVCQGEEIPRKGGPGITRSDLLVINKKDLAPYVGADLGVMERDAARMRAEKPFVFSDMKRGDGVERIVEFLTVHGGL
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_SHESW
Sequence: MTQDEMKKAAGWAALKYVEEGSIVGVGTGSTVNHFIDALATMKDDIEGAVSSSEASTQKMKALGIPVYDLNSVDRLSVYVDGADEINDRMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVNILGEFPLPVEVIPMARSYVARQLVKLGGDPVYRQGVVTDNGNVILDVYNLKILNPKELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTTK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.