PharMolix/UniProtQA huggingface dataset:
Protein: PYRF_GEOTN
Sequence: MHTPFIVALDFPSKHDVQQFLRPFSGTPLFVKVGMELYYQEGPAIIAMFKEQGHAVFLDLKLHDIPNTVKQAMKGLARLGVDLVNVHAAGGRRMMEAAIEGLDAGTPSGAARPRCIAVTQLTSTDERMLHEELWISQPLEETVSHYAALAQASGMDGVVCSANEATLIKERCGASFLAVTPGIRFADDSVHDQVRVVTPRKARALGADYIVIGRSITRAADPLAAYSRLQHEWNGGETE
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: TEAD_HALED
Sequence: MFNRIMVPVDGSKGAVKALEKGVGLQQLTGAELYILCVFKHHSLLEASLSMVRPEQLDIPDDALKDYATEIAVQAKTRATELGVPADKVRAFVKGGRPSRTIVRFARKRECDLVVIGAQGTNGDKSLLLGSVAQRVAGSAHCPVLVV
What is the function of this protein?
ATP-binding protein that negatively regulates activity of the tripartite ATP-independent periplasmic (TRAP) ectoine transport system TeaABC.  May regulate uptake according to the ATP status of the cell.
What are the official names of this protein?
TRAP-T-associated universal stress protein TeaD, UspA domain transporter regulator TeaD.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_ARTS2
Sequence: MAVPKRKMSRSNTRARRSQWKATAPHLVKTVENGQVTYSLPHQAKVVTDSAGTALFLEYKGRKVADV
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: QUEA_SHIDS
Sequence: MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDADRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GH315_ARATH
Sequence: MLPKFDPTNQKACLSLLEDLTTNVKQIQDSVLEAILSRNAQTEYLRGFLNGQVDKQNFKKNVPVVTYEDIRSYIDRIANGEPSDLICDRPISVLLTSSGTSGGVPKLIPLTTEDLEQRISFSSLYAPLLYKHIDGLSEGKSLIFYFVTRESKTANGLMVRTMVTSFLKSIKQTNSFLWDSLQVSPHAITTCADTTQSMYCQLLCGLLERDNVARLGAPFASSFLKVIKFLEDHWPELCSNIRTGRLSDWITDATCTSGIGKFLTAPNPELASLIEQECSKTSWEAILKRLWPKAKCIESIITGTMAQYIPLLEFYSGGLPLTSSFYGSSECFMGVNFNPLCKPSDVSYTIIPCMGYFEFLEVEKDHQEAGHDPTEKPVVVDLVDVKIGHDYEPVVTTFSGLYRYRVGDVLRATGFYNNAPHFCFVGRQKVVLSIDMDKTYEDDLLKAVTNAKLLLEPHDLMLMDFTSRVDSSSFPGHYVIYWELGSKVKDAKFEPNRDVMEECCFTVEESLDAVYRKGRKNDKNIGPLEIKVVKPGAFDELMNFFLSRGSSVSQYKTPRSVTNEEALKILEANVISEFLSRKIPSWELHELHSGR
What is the function of this protein?
Indole-3-acetic acid-amido (IAA) synthetase that catalyzes the conjugation of amino acids to auxin specifically using the auxin precursor indole-3-butyric acid (IBA) and glutamine and, possibly, cysteine as substrates (PubMed:29462792, PubMed:30315112).  Displays high catalytic activity with the auxinic phenoxyalkanoic acid herbicides 4-(2,4-dichlorophenoxy)butyric acid (2,4-DB) and to some extent 2,4-dichlorophenoxylacetic acid (2,4-D) as substrates, thus confering resistance to herbicides (PubMed:30315112).
What are the official names of this protein?
Indole-3-acetic acid-amido synthetase GH3.15, Auxin-responsive GH3-like protein 15, AtGH3-15, Protein GRETCHEN HAGEN 3.15.
What is the protein family that this protein belongs to?
Belongs to the IAA-amido conjugating enzyme family.
Protein: RL22_NEIG1
Sequence: MRVNAQHKNARISAQKARLVADLIRGKDVAQALNILAFSPKKGAELIKKVLESAIANAEHNNGADIDELKVVTIFVDKGPSLKRFQARAKGRGNRIEKQTCHINVTVGN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RIMP_STRPS
Sequence: MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVDKPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGKYIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3181_SACD2
Sequence: MRLLVISGRSGSGKTSALHLLEDEGFTCIDNLPVKLLPALIEQIGDAPHASKHKFAIGIDARNLNSDLSQIESLIKDNLPANAECLVVYLDTSREVLLKRFSETRRKHPLSDQNTGLNEAIAKEKVILEPVAAAADITVDTSHMSLHELRSTIKRLVVGEESKGMAIMFKSFGFKYGVPVDADFIFDVRCLPNPYWSPELRSQSGLEAGVIEFLNSQQEVDDMFDDICAFVQKWAPSFQANNRSYLTVAIGCTGGMHRSVYLAERLAAELKKGYANVQTRHRQLEQKPGA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein Sde_3181.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: MEL1_YEASX
Sequence: MFAFYFLTACISLKGVFGVSPSYNGLGLTPQMGWDNWNTFACDVSEQLLLDTADRISDLGLKDMGYKYIILDDCWSSGRDSDGFLVADEQKFPNGMGHVADHLHNNSFLFGMYSSAGEYTCAGYPGSLGREEEDAQFFANNRVDYLKYDNCYNKGQFGTPEISYHRYKAMSDALNKTGRPIFYSLCNWGQDLTFYWGSGIANSWRMSGDVTAEFTRPDSRCPCDGDEYDCKYAGFHCSIMNILNKAAPMGQNAGVGGWNDLDNLEVGVGNLTDDEEKAHFSMWAMVKSPLIIGANVNNLKASSYSIYSQASVIAINQDSNGIPATRVWRYYVSDTDEYGQGEIQMWSGPLDNGDQVVALLNGGSVSRPMNTTLEEIFFDSNLGSKKLTSTWDIYDLWANRVDNSTASAILGRNKTATGILYNATEQSYKDGLSKNDTRLFGQKIGSLSPNAILNTTVPAHGIAFYRLRPSS
What are the official names of this protein?
Alpha-galactosidase 1, Alpha-D-galactoside galactohydrolase 1, Melibiase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIG2_YEAST
Sequence: MPKKQTNFPVDNENRPFRCDTCHRGFHRLEHKKRHLRTHTGEKPHHCAFPGCGKSFSRSDELKRHMRTHTGQSQRRLKKASVQKQEFLTVSGIPTIASGVMIHQPIPQVLPANMAINVQAVNGGNIIHAPNAVHPMVIPIMAQPAPIHASAASFQPATSPMPISTYTPVPSQSFTSFQSSIGSIQSNSDVSSIFSNMNVRVNTPRSVPNSPNDGYLHQQHIPQQYQHQTASPSVAKQQKTFAHSLASALSTLQKRTPVSAPSTTIESPSSPSDSSHTSASSSAISLPFSNAPSQLAVAKELESVYLDSNRYTTKTRRERAKFEIPEEQEEDTNNSSSGSNEEEHESLDHESSKSRKKLSGVKLPPVRNLLKQIDVFNGPKRV
What is the function of this protein?
Involved in glucose repression of the SUC2 gene.
What are the official names of this protein?
Regulatory protein MIG2.
What is the protein family that this protein belongs to?
Belongs to the creA/MIG C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PROA_SALPK
Sequence: MLEQMGIAAKAASYKLALLSSGEKNRVLEKIADELEAQMESILSANVQDVEQARANGLSEAMLDRLALTPARLKAIADDVRQVCNLADPVGQVIDGGLLDSGLRLERRRVPLGVVGVIYEARPNVTVDVASLCLKTGNAVILRGGKETHRTNAATVRVIQKALKACGLPEAAVQAIDNPDRSLVNEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIFVDSSADIAPALKIIVNAKTQRPSTCNTVETLLVHQDIAERFLPVLSKQMAESGVTLHGDETVMQVLHGPAKLVPLKPEELDNEFLSLDLNVVVVENMDGAIGHIREHGTQHSDAILTCDMHNAARFVNEVDSAAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGFGDGTIRA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMG_NOSP7
Sequence: MTNLLPEMAEIWQQTLNWQPTVQQQEQFQRLYELILEGNRQLNLTRITDPQEFWEKHLWDSLRGILPLLSGNLPPASPTIIDIGTGAGFPGVPVAMTVPNCTITLLDSTQKKITFLDNILTELALTNTKTIVGRAEKIGQHPQHRMAYDIALIRAVGAVSVCAEYTLPLLKQGGLAIIYRGNWTKDETTALQNAVKLLGGVIESIEQFTTPLSHSIRHCVYLRKVATTPVQFPRPIGVPTQKPL
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RMUC_HAEIN
Sequence: MHQELSKTTQDYNQLASKFDELSSIKNQFEQQTIKVQTENQGLQYRLTERDEQIHHLTQERQNLTEKLTALSQELTGLQTTLTEKEKYFSAQQQNFEQSKQQLGVEFQNLANRILDEKSRSFSQSNQTALETLLKPFREQIEGFQKRVNEIHSESVKGNAGLEAEIKKVLEIGLNMSQEASNLTSALKGEKKTLGNWGEVQLERALQLAGLEENVHYRAQAHFKDEQGGRNYPDFVLNLPDEKHLIIDSKMSLVAYESAVNSEDDFERERLLKEHISALKTHINDLHKKDYSNLIGMCSPNFVLMFIAVEPAYIEALKADPALFNYGYERNVIMVSHTTLMPILRTVANLWRIERGNAEAKEIAEKAGEIYNQICLVAERLNKLGNTLSTVSNQYNSTVTALVGQQGLVGKVERFKTLSAKANKTMPDVDLLNNQLDLARLNVLNQENLQ
What is the function of this protein?
Involved in DNA recombination.
What are the official names of this protein?
DNA recombination protein RmuC homolog.
What is the protein family that this protein belongs to?
Belongs to the RmuC family.
Protein: RL5_SULDN
Sequence: MARMKDKYLALKAELQADLGIKNPMQTPALEKIVISVGAGFAMKDNKLIQNIEDTITTIAGQKASTVIAKKSVAGFKVREGMPVGVRVTLRGEKMYNFFDRLVSMALPRVKDFRGVPRNGFDGRGNYNFGLQEQLIFPEVSYDSVMQIHGMNITVVTSAESDKAGFALLEKMGMPFSKGSN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: FBK91_ARATH
Sequence: MITDLPKDLIEEILSRVSMTSMRVVRLTCKSWNTLSNSESFKKMHIGKVTSTREGESRVIMLIDYNLFLMSAVLMDDVDPSIEFKGKLSCLKEQVKISQVFHCEGLLLCILKDDTRIVVWNPYRQETRWIIPRYSHRPYVMNNIRYALGYENNKSGRSLKLLRFIDYCYTEKHICWHEIYDFDSDLWTTLDVTPHWYILSNWSCVQGVSLKGNTYWCAREENSDGYNHIICFDFTRERFGPLLPLPVNVIDNEYEYVTSSCVREGKIAALFQHNDSYPYELEIWITTKIEAEMVSWNKFLRIDIEPNNNIMVPFIYGGFFIDEEKKKVALGFDEEFGRKTFNIIGEDGYFREFDRITFNIIEEAGERAGVNCGSYVCSYVPSLVRIKKPAQGKRKRQSSLEKLRFDQNTWIFDSIYQATASQIRRRRPTR
What are the official names of this protein?
F-box/kelch-repeat protein At4g33290.
Protein: OTUBL_CAEBR
Sequence: MVNDTSENQPTTAGIVTTTEDELILQDQQMKRIEDEQKASPLVGEKMPCATLVSLYDQETAPAFFEKANELAKVYSHIRFIRGDGNCFIRAIQVGLVEILLNDKERLVKFIASCKEWTERLVKLGFPDWTCTDFCEFFIEFIEKVRDGIHQKEDVFRIFNDDNTANYLLMFFRLITSGYLKEHAAEYEPFLDEGMSLAQYCETEIEAMWKESDHLGIIALVRALNIRIRIEYMDRNAAPNGGTHHNLPDGHDNATFTPDITLLYRPGHYDLIYKAPAETSKPALPPVA
What is the function of this protein?
Hydrolase that can remove conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation.  Specifically cleaves 'Lys-48'-linked polyubiquitin (By similarity).
What are the official names of this protein?
Ubiquitin thioesterase otubain-like, Deubiquitinating enzyme otubain-like, Ubiquitin-specific-processing protease otubain-like.
What is the protein family that this protein belongs to?
Belongs to the peptidase C65 family.
Protein: AAM_RHOER
Sequence: MTEQNLHWLSATEMAASVASNNLSPNEIAEAMIQRVDAVNPSINAIVQFDREQVTRDAAELSRQQEAGEKLGPLHGVPFTIKDLTAVDGLPTTFGMKPMADNIATGNAVVVDRLRGAGGLFLGKTNTPESGYYGGTDNHLYGPTHNPWKLGNSAGGSSGGASAAVAAGLGPLAEGSDGAGSVRIPSALCGVVGLKPTTGVIPQTILAGRFYNWAYHGPITRTVADNALMLDIMAGPDNADPLSIERAETSYVEASKGDVKGLRVAWSPNLGLGHVDPEVLAVCLDALAAFEELGAQITEATPQWGNPSESMWSGIWVPGFASEYDLLDWENQRGEVDDYLIEIMHEAERLTGVDVGRADAFRGDMWDTWTTFMNDYDVLVSPTLASATFPLRQFAPSWLEGASLREQLLDWLFTYPYNMLNNPAITVPAGFTADGRPVGLQIAARHRRDALVLRTAANFEAVRPWADKKPADSLVVA
What is the function of this protein?
Amidase with broad substrate specificity, catalyzing the hydrolysis of a wide range of N-substituted amides, and, to a lesser extent, the hydrolysis of non-substituted amides.  Acid para-nitroanilides (4'-nitroacetanilide, Gly-pNA, Ala-pNA, Leu-pNA) are the best substrates for this enzyme.  N-substituted acrylamides (isopropyl acrylamide, N,N-dimethyl-aminopropyl acrylamide, and methylene-bis-acrylamide), N-acetyl derivatives of glycine, alanine and leucine, and aliphatic amides (acetamide, acrylamide, isobutyramide, n-butyramide, and valeramide) can also be used as substrates but with less efficiency.
What are the official names of this protein?
Acylamidase.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: NORR_SHIBS
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKGVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMMPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYRFPGNVRELEHAIHRAVVLARATRNGDEVILEAQHFAFPEVTLPPPEAAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGMKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: SYS_HAEI8
Sequence: MIDPNLLRNNLAEVAEKLKVKRNFMLDTEKLTALEDQRKNLQVTTENLQAERNARSKAIGAAKVRGEDIAPLLAEMDDMGNQLTEAKAQLDAVLAEINQIALSIPNLPADEVPLGKDDTENKEILRWGTPHTFDFEVKDHITLGEEANGLDFAAGAKLAGARFAVMKGQIAKMHRALAQFMLDLHTEQHGYLETYVPYLVNHATLYGTGQLPKFGEDLFHTLALEGEQPYALIPTAEVPVTNLVRDVIIDEAELPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVDPDKSMEALEELTGHAEKVLQLLNLPYRKVLLCTGDMGFGSCKTYDLEVWLPAQNTYREISSCSNMWDFQARRMQARCKAKGDKKTRLVHTLNGSGLAVGRTLVAVLENYQNADGSITVPEELRPYMGGLDVIGK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP4_BOVIN
Sequence: MAEGGGYRERPDAETQKSELGALMRTTLQRGAQWYLIDSRWFKQWKKYVGFDSWDMYNVGEHNLYPGPIDNSGLFSDPESQTLKEHLIDELDYVLVPAEAWNKLLNWYGCVEGQQPIVRKVVEHGLFVKHCKVEVYLLELKLCENSDPTNVLSCHFSKADTIATIEKEMRKLFNIPAERETRLWNKYMSNTYEQLSKLDNTVQDAGLYQGQVLVIEPQNEDGTWPRQTQQSKSSTAPSRNFTTSPKSSASPYSSVSASPIANGDSTNTSGMHSSGVSRGGSGFSASYNCQESPLTHVQPGLCGLGNLGNTCFMNSALQCLSNTAPLTDYFLKDEYEAEINRDNPLGMKGEIAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANGRPDAVVAKEAWENHRLRNDSVIVDTFHGLFKSTLVCPECAKVSVTFDPFCYLTLPLPLKKDRVMEIFLVPADPRCRPTQYRVVVPLMGAVSDLCEALSKLSGIAAENMVVTDVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSPDGSECVTLPVYFRERKSRPSSTSTGAVLYGQPLLVSVPKHKLTLESLYQAVCERISRYIKQPLPDESGSSPLELGACNGSRSGCAGEDEEEMEHQEEGREQLSETEGSGDDEPGSDHGEATQKKNKGRPCPRRLFTFSLVNSYGTADINSLATDGKLLKLNSRSTLAIDWDSETRSCYYNEQESETYEKHVSMLQPQKKKKTAVALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPVRGLNMSEFVCDPSARPYVYDLIAVSNHYGAMGVGHYTAYAKNKLNGKWYYFDDSNVSLACEDQIVTKAAYVLFYQRRDDEFHKTPSLSFPGSSDGGARPSSSQQGTGDDETYSMDTN
What is the function of this protein?
Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins.  Deubiquitinates PDPK1.  Deubiquitinates TRIM21.  Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface.  Deubiquitinates HAS2.  May regulate mRNA splicing through deubiquitination of the U4 spliceosomal protein PRPF3.  This may prevent its recognition by the U5 component PRPF8 thereby destabilizing interactions within the U4/U6. U5 snRNP.  May also play a role in the regulation of quality control in the ER.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 4, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and cytoplasm. Exported to the cytoplasm in a CRM1-dependent manner and recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor. The relative amounts found in the nucleus and cytoplasm vary according to the cell type.
Protein: TIM22_XENLA
Sequence: MGSNVTPPGDGTLQYSLIMQHLVGDKRRPVELIPGGLGGIPTPIKPEEQKMMERVMESCGFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPLRTPTAKEVLRDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVMSGCITGGAIGFRAGLKAGVLGCGGFAAFSAVIDYYLR
What is the function of this protein?
Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel.  Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim22.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DUS28_HUMAN
Sequence: MGPAEAGRRGAASPVPPPLVRVAPSLFLGSARAAGAEEQLARAGVTLCVNVSRQQPGPRAPGVAELRVPVFDDPAEDLLAHLEPTCAAMEAAVRAGGACLVYCKNGRSRSAAVCTAYLMRHRGLSLAKAFQMVKSARPVAEPNPGFWSQLQKYEEALQAQSCLQGEPPALGLGPEA
What is the function of this protein?
Has phosphatase activity with the synthetic substrate 6,8-difluoro-4-methylumbelliferyl phosphate (in vitro) (PubMed:24531476, PubMed:29121083).  Has almost no detectable activity with phosphotyrosine, even less activity with phosphothreonine and displays complete lack of activity with phosphoserine (PubMed:29121083).  The poor activity with phosphotyrosine may be due to steric hindrance by bulky amino acid sidechains that obstruct access to the active site (PubMed:29121083).
What are the official names of this protein?
Dual specificity phosphatase 28.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: GLMU_BURCJ
Sequence: MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARTLQPSRLVVVVGHGAEQVQAAVAAPDVQFAVQAEQLGTGHAVRQALPLLDPAQPTLVLYGDVPLTRASTLQRLVDAAREGRYGILTVTLDDPTGYGRIVRDASGFVTRIVEQKDASPEELKIAEINTGIIVTPTAQLSMWLGALKNENAQGEYYLTDVVELAIEAGFEVVTSQPDEEWETLGVNSKAQLAELERIHQRNVADALLVDGVTLADPARIDVRGTLRCGRDVSIDVNCVFEGNVTLADNVTIGANCVIRNASVGAGTRIDAFTHIDGAALGANTVIGPYARLRPGAQLADEAHVGNFVEVKNAVIGHGSKANHLTYIGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVGSDTQLVAPVRVGRGVTIAAGTTIWKDVAEGVLALNEKTQTAKSGYVRPVKKKS
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_FRATW
Sequence: MLDKIWYRSKPNLLSRVLQPISLVFIDIANKRKIKQQLKQYKSKIPIIVVGNISVGGTGKTPVVRMLAQQYLAQDKKPAIISRGYGAKADNYPFEVTSGTLATQCGDEPAMLFDALQAQVPIVIAPERVQAVKYIEKNFPDTDIIMSDDGLQHYKLARDKEIVVVDAIRMFGNKLCLPAGPLREPIERLKEVDQIIVIGNCSDKDKELLKNYKNVTYAKVVATEFVNILTAKKVAKTEFNHQNAIAIAGIGNPTKFFKTLEESAINITAKKVFKDHHKFTQSDFEGIDSDITVVMTYKDAIKCKNFAKANWWYLDIALDINV
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: LYRM9_PHYPA
Sequence: MSQAVKQAYREVLKLVKRLPPPSRGYYAQYARENFVTYSEVEDPESIRSLLARVHHHTCWVLKKVR
What are the official names of this protein?
LYR motif-containing protein PHYPADRAFT_186863.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. LYRM9 subfamily.
Protein: BIOF_NITMU
Sequence: MLNDLDSIHQTDEGLREYLRSRGNRSLYRYRLTLESPQAPRITVSGREYLAFCSNDYLGLANHPELIAALCEGATQYGVGAGTSHLVSGHSRAHHLLEEALASFTRFPRALLFSTGYMANAGVVTALTGRGDAVFGDKLNHASLNDAALLSRARLSRYPHLDLATLERQLAASPARRKLVISDAVFSMDGDIAPLPELLELCERYDAWLLLDDAHGFGVLGNQGRGSLAHFNISSPRIIYMGTLGKAAGVFGAFVAAQEEIIETLIQCARSYIYTTATPPFLSHALLKSLELIAGGAGRREKLAQLTKLLKQECHPLRWQLLPSDTPIQPLVMGENAEALQVSEALRQKGILVTAIRPPTVPEGTARLRISLSSSHDIEDVMELGAALREIDRDME
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RNPA_STRPG
Sequence: MKKTYRVKREKDFQAIFKDGKSTANRKFVIYHLNRSQDHFRVGISVGKKIGNAVTRNAVKRKIRHVIMALGHQLKSEDFVVIARKGVESLEYQELQQNLHHVLKLAQLLEKGFESEEKH
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: MIAA_GEOTN
Sequence: MTEKIVVIVGPTEVGKTKLGIALAKKLGGEIISGDSMQIYKGMDIGTAKVKPDEMEGVPHHLLDIKEPCEPFSVVEFQRLARALITDISARGRLPIIVGGTGLYIQAAIYDYRFSDAPSDEAYRRALRQLAAEQGAEALHEQLKAVDPESAARIHPNNVRRVIRALEVYHCTGKPFSEWQRGQQRQLLYETALIGLTAERSVLYRRINERVDEMIAEGLIEEVRSLYDRGLRDCQAVQAIGYKELYDYFDGRVSLDEAIEQLKQNSRRYAKRQLTWFRNQMPVEWFDMTDPEKFAVKVEEIFRYIAGKLRLEANI
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.