PharMolix/UniProtQA huggingface dataset:
Protein: G6PI_LACLS
Sequence: MAHIKFDYSKLTPFVAENELYEIQWQIDGAAKLLHEGKGAGSDYIGWLDLPEDYDKEEFARIQKAAKKIKSDSEVLIVIGIGGSYLGARAAIDFLSNSFVNLQTAEERKAPRILYAGNSISSSYLADLVDYVADKDFSVNVISKSGTTTEPAIAFRVFEEMLVKKYGREEANKRIYATTDKEKGAVKVNADANNWETFVVPDSVGGRFSVLTAVGLLPIAASGADITALMEGANAARKEYTSTNVHENDAYAYAALRNILYRKGKFSEILINYEPSLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQWIQEGTRTVFETAIRIEKPRKNINIPELDADLDGLGYLQGKDVDFVNKKAADGVLLAHTDGNVPNMIVTLPEQDEFTLGYAIYFFELAIGVSGYLNGINPFNQPGVEAYKKNMFALLGKPGFEELSKELNDRL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_SYNE7
Sequence: MGQAAAITMPIDPRNLNTLWSSVLAESFVRLGLQTVVICPGSRSAPLAIAFAEHPEIDAIPILDERSAGFFALGRAKASHRPVALICSSGTAGANFYPAVIEAKESGVPLLVITADRPPELRQCHAGQAIDQLRLFGSYALWEAELALPVLDLGLLRYLRQTAQQAWQQALRGGPVHLNQPLREPLAPIADPATQTWLAQQWPGENFFAELLTAVPTPQIQQPLPPLPSQGLITVGPIAPEDPAAFVQAIAQLSAHLGWPVLSDAVTPLRQFADHCPRLISSYDLILRQPHWRASLQPEAVLQIGELPTSKELRLWLTEQTCPRWIVSPRPENFDPLHGSSHHLPVTVEAIAIPATIAPASDYSRQWQQAETAVQAAIAQHLAQVPDLTEPGIARLLSQHLPAQTPIFVANSTPIRDLEWFWLANDQRRSLYCSRGANGIDGTLSTAIGIAHQNRPSVLITGDLSLLHDSNGFLQRSQLQGHLTVVLIDNSGGGIFELLPIRDCGPSFEPFVATPQTVDFAALCQAYGVDYQAIATEAELIKAIQTLPTSGIRVLHLFTDRRQNAAWRRALFAELAAIPSQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: INSF1_ECOLI
Sequence: MKYVFIEKHQAEFSIKAMCRVLRVARSGWYTWCQRRTRISTRQQFRQHCDSVVLAAFTRSKQRYGAPRLTDELRAQGYPFNVKTVAASLRRQGLRAKASRKFSPVSYRAHGLPVSENLLEQDFYASGPNQKWAGDITYLRTDEGWLYLAVVIDLWSRAVIGWSMSPRMTAQLACDALQMALWRRKRPRNVIVHTDRGGQYCSADYQAQLKRHNLRGSMSAKGCCYDNACVESFFHSLKVECIHGEHFISREIMRATVFNYIECDYNRWRRHSWCGGLSPEQFENKNLA
What is the function of this protein?
Involved in the transposition of the insertion sequence IS3.
What are the official names of this protein?
Transposase InsF for insertion sequence IS3A.
What is the protein family that this protein belongs to?
Belongs to the transposase IS3/IS150/IS904 family.
Protein: CIDA_BACSU
Sequence: MKKLLLTVIQIALLFIFARLINWVTALLHINIPGSIIGIVILFTLLHFNIIKLEWIELGAAWLLGELLLFFIPSAVGVIEYGDIMSKFGVSILLVVIISTFVVMVSTGTLTQLIAKRKEKKHTCSSEL
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: BARF1_EBVB9
Sequence: MARFIAQLLLLASCVAAGQAVTAFLGERVTLTSYWRRVSLGPEIEVSWFKLGPGEEQVLIGRMHHDVIFIEWPFRGFFDIHRSANTFFLVVTAANISHDGNYLCRMKLGETEVTKQEHLSVVKPLTLSVHSERSQFPDFSVLTVTCTVNAFPHPHVQWLMPEGVEPAPTAANGGVMKEKDGSLSVAVDLSLPKPWHLPVTCVGKNDKEEAHGVYVSGYLSQ
What is the function of this protein?
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1.  May inhibit interferon secretion from mononuclear cells.  Exhibits oncogenic activity in vitro.
What are the official names of this protein?
Secreted protein BARF1, 33 kDa early protein, p33.
What are the subcellular locations of this protein?
Secreted. Note=Massively secreted in the serum of EBV-induced nasophyryngeal carcinoma patients.
Protein: ACCA_VIBC1
Sequence: MSLNFLEFEKPIAELEAKIEALRDVSRHGGDSAVDLDKEIEQLEKKSLELKKKTFSNLGAWETAQLARHPLRPYTLDYIKHAFDEFDELAGDRAFADDKAIVGGIARLEGRPVMIIGHQKGRETKEKVKRNFGMPKPEGYRKALRLMEMAERFNMPIITFIDTAGAYPGVGAEERGQSEAIATNLKVMSGLKVPVICNVVGEGGSGGALAIGVGDYVNMLQYSTYSVISPEGCASILWRDSDKAPQAADAMGLTAPRLKELELIDEIIEEPLGGAHRDHAQMAANMKANLLRQLEDLEQLDHETLLERRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_STRGC
Sequence: MFFIEIIKSVIFGIIEGITEWLPISSTGHLILVQEFIHYQKQNAAFMEMFNVVIQLGAILAVVFIYFDKLNPFKPDKTPRQVQKTWQLWAKVVVASLPAVIIGIPLDNWFEKNFHNFVSVAIMLIIYGIAFILIERRNQEVEPTVTNLEKLPYKTALYIGFFQVLSLFPGTSRSGATIVGGLLNGTSRSVVTEFTFFLGIPVMFGASGIKVLKFILKGNSLDLGQLTLLLVAMIVAFGVSMYVIRFLTDYVKKHDFTVFGKYRIGLGALLLIYWVFKALFAK
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS21_VESOH
Sequence: MPSIKVRENEPFDIALRRFRRICDRAGVITDVRKKEFFEKPTWVSKRMKAAAVKRTHKEMAKNRVYRKRMY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: HNRH2_HUMAN
Sequence: MMLSTEGREGFVVKVRGLPWSCSADEVMRFFSDCKIQNGTSGIRFIYTREGRPSGEAFVELESEEEVKLALKKDRETMGHRYVEVFKSNSVEMDWVLKHTGPNSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGMTLPVDFQGRSTGEAFVQFASQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRGYNSIGRGAGFERMRRGAYGGGYGGYDDYGGYNDGYGFGSDRFGRDLNYCFSGMSDHRYGDGGSSFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPMRVHIEIGPDGRVTGEADVEFATHEDAVAAMAKDKANMQHRYVELFLNSTAGTSGGAYDHSYVELFLNSTAGASGGAYGSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYDQVLQENSSDYQSNLA
What is the function of this protein?
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm.  Binds poly(RG).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein H2, hnRNP H2, FTP-3, Heterogeneous nuclear ribonucleoprotein H', hnRNP H'.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: FTSH_RICPR
Sequence: MNNQGRSILAWAALFIFVILLFNVFQSDGLLGVRNNITFSDFLTRVDEKTINSVKIQGRVIEGTANDGSTFSTYSPDYPDLVNRLTSNDVNIEVVPLETRMNTFLGFLISWFPMLLLIGVWVFFMRQMHGGGKAMGFGKSKARLLSDKGPKITFKDVAGIDEAKEELTEIVDFLRDPSKFQKLGGKIPKGCLLIGPPGTGKTLLAKAIAGEANVPFFSISGSDFVEMFVGVGASRVRDMFEQGKRNAPCIIFIDEIDAVGRHRGIGMGGGNDEREQTLNQMLVEMDGFEANEGVVIIAATNRPDVLDRALLRPGRFDRQIAVANPDINGREQILKVHLKKIKYNSTVLARIIARGTPGFSGAELANLVNEAALIAARLGKKEVDMHDMEEAKDKVLMGVVRRSIAMSEKEKRLTAYHEGGHALVGLYCPAASPIHKATIIPRGNALGMVQRLPETDEYSQNREQMESSIAVYMAGRVAEEIIFGRNKVTSGASSDIKGATNIARAMVTKAGLSDLIGPIFHGSNSDDMYGRQSSNEISEATAELIDAEVKRIITQGYEFAKDILTKHIDQLHTLANALIEYETLSGQQIKNLLSGRALDSEEENKFPFNDSHTIKIDKENLHEKVKSTKDKKENIIS
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: DABA_RALP1
Sequence: MTTTSLGADAAHTHAMVPSAIPPEGSDAAGPDDTLMQQMQAACAQACRAIAPAWPLDRAIAVNPHWGRVDMPVRRVAARMAVLGGIQVFPTRRSQQQAWVAGRITPADLADALAQLPAARAAGLTEAKCVEALRRHELPPRLPLLIDVLDNDPQRHTRLSWRQAITHQVSQTCAAYFDVHQADWQPERADGLYGFWRDTLQHDHGIGLLMGLPDLGRRLDALPATPLDAEHWALNQLGLPQPVWADYLEAVLLTVNGWASWCAYLGWQAAQEGREDPHLRDLLAIRLAWGAIVQECRDDASTRMAFAALQAEWQQAPSALAEAEAALLVDEVWQLALEAGYQRQLAHRLAGAGALPPVPQDIEVQAAFCIDVRSEPLRRALECVWPAVQTIGFAGFFGLPVAYTPLGTAARRPQLPGLLAPTMEVSDRIDAAQGPDGMPDPAAERAAERARRHRLGASAQVDGASRWPSAAFSYVEVAGVGYLGKLWRWLRPSTEARSRADLTGLPSRYRAVCRPHLHAESVETKAALAARVLRAMGLAEHLAPLVLFVGHGSQTSNNAHAAALDCGACCGQTGEVNARSLALLLNEPPVRAALQAHGITVPEDTVFAAALHNTTTDEIEGFDLDRLPPAARARWDHLQSVLKHASDQVRRERAPSLGLDPRAPHDDLLTQLRRRANDGAQTRPEWGLAGNAAFVIAPRHRTQGVVLDGRSFLHDYDASRDHDGSVLELLMTAPMLVTHWINWQYHASMCDPVHLGSGNKLLHNVVGGSIGVFEGNGGDLRIGLSRQSLHDGQRWIHEPLRLTVLIDAPETAIERVVDKHPIVRQLVDNGWLHLWRFGPQDLQRYAAGQWRPLTSRHATC
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ANFD_LITCT
Sequence: MHFCHIVGWGLVLAVLYLRTEAKPVAQAHQKSLRALLGEELAEYLVSGERGERSIDPKTRARLLRDIRADTRSRAAWTRLLNEHPNSRKIKGINKKGTSKGCFGLKLDRIGAMSGLGC
What is the function of this protein?
Exhibits natriuretic and vasodepressor activity.  Has a cGMP-stimulating activity.
What are the official names of this protein?
C-type natriuretic peptide 2, CNP II.
What is the protein family that this protein belongs to?
Belongs to the natriuretic peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_STRPD
Sequence: MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDYAEKARHVDDEPYGGGQGMLLRAQPIFDTIEQIEAKKPRIILLDPAGKPFTQAYAEELALEEELIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMVDATVRLIPQVLGKESSHQDDSFSSGLLEYPQYTRPYDYRGMTVPDVLMSGHHERIRLWRLEESLRKTCLRRPDLLEHYNFSEEERKLLDKIKEALDQGED
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_STRPJ
Sequence: MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLVVNVPDFIEAGQKLVINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_GALME
Sequence: MRTWSNFNLQNSASPLMEQIIFFHDHTLIILIMITILVGYIMINLFFNKFINRFFLVGQMIELIWTVLPAITLIFIALPSLRLLYLLDELNNPLITLKTIGHQWYWSYEYSDFNNIEFDSYMIASNELPLNNFRLLDVDNRIILPMNNQIRILVTATDVIHSWTIPSLGVKVDANPGRLNQTNFFINRPGIFYGQCSEICGANHSFMPIVIESISIKNFINWINNYSY
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GATC_SINFN
Sequence: MSVDLATVKRVARLARIAVSDEEAERMTGELNGILGFVEQLSEVNVDGVEPMTSVMPMEMKKRDDIVADGDKAADIVANAPNSDRDFFLVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: Y344_CHLMU
Sequence: MTVIYFVLAALALGFLILIHELGHLLAAKAVGMTVESFSIGFGPALVRKKMGSIEYRIGAIPFGGYVRIKGMDRNDKEISEDREKTVYDIPGGFFSKSPWKRIFVLAAGPLANILVALFAFGILYFSGGRTKPFSEHTSIVGWAHPSLEQKGLRPGDRIFLCNGQVYSGNKMAFSSSLLDRKLSLQGEHPAYFSEAESFSLDVPFNPSLEGVPCLGASYLLYRGSEPLPEKSPLIDAGLSEGDRLVWMDGALVFSGVQVSQILNEKKAFLRIERQGKIVFVRQSRVLAGDLQLTSYFKNELIDCQYEAGLKGKWASLYMLPYIINSDGFVESKINLLNTDQQSLDYHLELGDRIVAVDGIPVMSNADILRLVQDHRVSLIFQRMSSGQLSVLDQKAADKAFIDSYDMDDLLRVAGSVGEEREVSHLGEYRLVTRVQPKPWVHIYSEELLDKQRALASKFRDEQEKRYYLERIESEKQRISLGIPLKDLAVQYNPAPLVLMGESISDSLRTVKALGSGRLSPQWLSGPVGIVRILHTGWSMGIPEALSWIGLISINLAVLNLLPIPVLDGGYILLCLWESVSRRRLNMRLIEKGLVPFMILLILFFVFLTLQDLSRVFIG
What are the official names of this protein?
Putative zinc metalloprotease TC_0344.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RFCL_PYRAE
Sequence: MALPWIEKYRPKSFAEIVNQEEAKYTLASWICLKFRAPKEFCTRWAKKRDKEVAEAKAILLAGPPGVGKTTLVHALAREIRYELIELNASDVRTADRLRQVIGRGLRESSLFGFEGKMVLFDEVDGLHVKEDKGGLEEIIEIIETAKIPIIMTANNPYDPKFRPLRDISLVVNLKRLSEEEVVEVLRRICTSEGAKCEEEALRSIAKSSMGDLRAAINDLQMYLSGGRRILTLDDIKRVGERNPQLSMFEILDRVYKARWFDEARAVSFNPSFDWEQYFIWALESIPVVYKDLEIASTAYDRLSKADVFMGRIKRTQEWELLPYALELALGGVSQIKGKPRLPPFIKYGFPQRLLLLAKSKEARRRRDALVEYLAQNLHASKSVIKSEIIYVLSALSKNNQSIIEKLSKALGINAIDIKSVL
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: VFB66_ASFWA
Sequence: MDIKRALILFLLFLVVLSNAFVDYIISNFNHAVTCRKPTYFGIVLQGIFLVILFSIVDYLINENIL
What are the official names of this protein?
Transmembrane protein B66L, pB66L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B66L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: EFTU_HELPG
Sequence: MAKEKFNRTKPHVNIGTIGHVDHGKTTLSAAISAVLSLKGLAEMKDYDNIDNAPEEKERGITIATSHIEYETENRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLSRQVGVPHIVVFLNKQDMVDDQELLELVEMEVRELLSAYEFPGDDTPIIAGSALRALEEAKAGNVGEWGEKVLKLMAEVDAYIPTPERDTEKTFLMPVEDVFSIAGRGTVVTGRIERGVVKVGDEVEIVGIRATQKTTVTGVEMFRKELEKGEAGDNVGVLLRGTKKEEVERGMVLCKPGSITPHKKFEGEIYVLSKEEGGRHTPFFTNYRPQFYVRTTDVTGSITLPEGVEMVMPGDNVKITVELISPVALELGTKFAIREGGRTVGAGVVSNIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WHIB3_MYCTO
Sequence: MPQPEQLPGPNADIWNWQLQGLCRGMDSSMFFHPDGERGRARTQREQRAKEMCRRCPVIEACRSHALEVGEPYGVWGGLSESERDLLLKGTMGRTRGIRRTA
What is the function of this protein?
A redox-sensitive transcriptional regulator.  Maintains intracellular redox homeostasis by regulating catabolic metabolism and polyketide biosynthesis.  Regulates expression of the redox buffer ergothioneine (ERG).  In concert with myothiol (MSH), another redox buffer, responds to low pH leading to acid resistance.  Senses changes in the intracellular redox state and helps mediate a metabolic switchover to preferred in vivo carbon sources (fatty acids).  The apo- but not holo-form probably binds DNA (By similarity).
What are the official names of this protein?
Redox- and pH-responsive transcriptional regulator WhiB3.
What is the protein family that this protein belongs to?
Belongs to the WhiB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULP1D_ARATH
Sequence: MTKRKKEVIDVDCSEKKDFVIDWSSAMDKEDEVPELEIVNTTKPTPPPPPTFFSDDQTDSPKLLTDRDLDEQLERKKAILTLGPGLPDKGEKIRLKIADLEEEKQRRVLEGSKMEVDRSSKVVSSTSSGSDVLPQGNAVSKDTSRGNADSKDTSRQGNADSKEVSRSTFSAVFSKPKTDSQSKKAFGKELEDLGCERRKHKAGRKPVTRLSNGWRLLPDVGKAEHSAKQFDSGLKESKGNKKSKEPYGKKRPMESSTYSLIDDDDDDDDDDDNDTSGHETPREWSWEKSPSQSSRRRKKSEDTVINVDEEEAQPSTVAEQAAELPEGLQEDICYPTRDDPHFVQVCLKDLECLAPREYLTSPVMNFYMRFLQQQISSSNQISADCHFFNTYFYKKLSDAVTYKGNDKDAFFVRFRRWWKGIDLFRKAYIFIPIHEDLHWSLVIVCIPDKKDESGLTILHLDSLGLHSRKSIVENVKRFLKDEWNYLNQDDYSLDLPISEKVWKNLPRRISEAVVQVPQQKNDFDCGPFVLFFIKRFIEEAPQRLKRKDLGMFDKKWFRPDEASALRIKIRNTLIELFRVSDQTE
What is the function of this protein?
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins.  Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5.  Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3.  Protease activity mainly directed at deconjugating SUM1 and SUM2 from their target proteins.  Regulates salt stress responses and flowering time.  Redundant with ULP1C.
What are the official names of this protein?
Ubiquitin-like-specific protease 1D, Protein OVERLY TOLERANT TO SALT 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: SUCC_EHRCJ
Sequence: MNIHEYQAKHILSRFGVSVPKGAIVHSLSEVDDAISKLHSKVIVVKAQIHAGGRGKAGGVVVCRTSDEAKASIKNMLGSTLVTHQTSKDGQKVRKVYLEEGCDIKKEYYISAIVNRKQSQVSIIFSTEGGVDIEEVASTSPEKVIVCNIDPLFGFQSFHGRNLCFDSNLSLDQTRKISDIAEKIYKVMLSTDANQVEINPLVETSSGNFIALDAKINFDDNALYRHPDIQELRDYDEEIKEEIEASKYGLNYIKMDGNIGCMVNGAGLAMATMDIIKYYGAEPANFLDVGGGASQKTVTEAFKIILSDKVDGILVNIFGGIMRCDIIANGIIAAIEEIRINVPLVVRLSGTNFELGKKLLDDSSLNIITANDLSEAAYNIVNIVKK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: MLC5_CAEEL
Sequence: MDDLADCREVFAYFDSKGDERISVQQVGDVLRALGQNPTEAEIHKCVGSFDREARLSFEDFVPIFQSVSKNREKHTVEEFVEGLSHFDKEGNGMINVAELRHLLTTLGERLSDEDVDQLLSGHNDSHGNVNISDFVRAVMNS
What is the function of this protein?
Required for cytokinesis and embryo elongation.  May regulate myosin II complex formation and/or the association of myosin with actin.  May be involved in the organization of mlc-4 and nmy-2 into bundles.
What are the official names of this protein?
Myosin-2 essential light chain.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Forms a filamentous structure during 2-fold embryonic stage which may co- localize with actin and whose formation may be regulated by mlc-4.
Protein: DNAA_AERHH
Sequence: MTASLWQQCLNRLQDELPSAEFSMWIRPLQAELSDNTLTLYAPNRFVLDWVRDKYLIRVNGIINELCGVDGPTLRFDIGNRPHPVAVARAPARGADPVNNSQKSWESKAEAKPEPNHKSNTNVNYTFENFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNAIKERKQDAKVIYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKADENQIHLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAINIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKLADLLSKRRSRSVARPRQLAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLKEESHDIKEDYSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_HERAR
Sequence: MAKRDFYEILGLGKNASDEEIKKAYRKLAMKHHPDRNPDSKGAEDKFKEAKEAYEMLSDPQKRDAYDRYGHAGVDPNMGGGGGGGGFADAFGDIFGDIFGQAGGGRGGRGGPQVYRGADLRYNLEITLEQAAHGYDTTIRVPSWDSCETCDGSGAKPGTSPINCTTCGGHGQVRMQQGFFSVLQTCPKCHGSGKINPSPCTACSGAGKIKRNKTLEVKIPSGIDDGMRIRSSGNGEPGMNGGPPGDLYVEIRIKQHAMFQREGDDLHCEIPISFAKAALGGEIEVPTLNGKASFTIPEGTQSGKTFRLRSKGIKGVRSGYAGDLFCHVVVETPVTLTEKQKELLREFELLTIEGGSKHSPQTKSWKDKVKEFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.