PharMolix/UniProtQA huggingface dataset:
Protein: M1249_ASFM2
Sequence: MEEVITIAQIVHRGTDILSLNNEEIEALVDEIRSTLKGSNDIKNIRLIDFLFTLKDFVNHVRAEQSKLPNLSMPMEAYIRQLLVNPDVIPIVSEKKKELRVRPSTRKEIFLINGTHLAVPAEVPIEIYGLKLRLKTFSPQCFMRMAEIGSFLPETLGYVASGANLTNFIRVFMKCVDQETWKKNGEGIVVTTKENIIQFTHQYIELYKFLRSGGHSWLINRLAEEMVHRKLDREDQGSHISSVIETEEIEPEENIKRVIFFLKELSTMYSVFPVFTSGYMPLLYDLYRAGYLEVLWNPVEQKFLQHAEQREKEQMILQQVDMKLTEVTTQARQYFKIMEEKIGRVQSDAIREILTMEGKVDDPNSILQEVIKACGKQEAELITTEYLNIKKQWELQEKNACAHLKLVKQLRSGLQYAESLKVLESIRVLYKEKNNTTNWNLCKACGFKLLCPHVDMLIQLQAAEASYDTMRTKLMKFSGINKEKENNQGLIYSYFCKICGEELAHFVQEDRTADVGVIGDLNSKLRIFIWQETMKACTFIHFGKLVDVKQFANIAVNVCLPLIYNIENIKKEEDYDPLTQLYAVIYIYAYILNLIYSSQKNKEFLTITIHGMKADSSLNAYVTFLLEKMTQQYSGIINQLSEITDQWIANNFREAFKKIIHQNGLQGLSVQDDTKVLLTEILLDPLYDYAATVARIDGSIPMHKPQTPKEAEYEFKTVIGRTPTELLSQKEFYDKIYTFKYRPDFTQLARLNDIYFQEESLRVWWGGRDEEKISTLIYLKAYELFLKYLQNAPNFNLELAEFKKYENAYGEQRALLAQQGFYNIFDPNTGRADQRTRLFEYKKLPISTLYDEKGLPHKWTIYVYKAIDSSQKPAEIEVSRKDVIKKIDNHYALADLRCSVCHVLQHEVGQLNIKKVQTALKASLEFNTFYAFYESRCPKGGLHDFQDKKCVKCGLFTYIIYDHLSQPELVHDYYNNYKDQYDKEKMSIHSIQMKKDIAVPSAETQPEPQQEPWTFDYGKIIKTAKILDISPAVIEAIGAMEGRSYADIKEGQGAPPPPTSMDDPRLMAVDSAVRIFLYNYNCLRHISTFNKPPMYIERLVKHLSYEEKEDLEKVLPNVVNEYHTTFKQLRVTDPASALLYSIEFLCISFLTLYEIKEPSWVVNIIREFALTELNTIIQSEKLLSKPGAFNFMIFGEDFVCSGEDSSMDDISAYSSPGLFGEDIIDQLDDPFSIEDVDISLDVLDNLAPQ
What is the function of this protein?
Together with the penton and the other minor capsid proteins (p17, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid.  In addition, blocks IFN-beta transactivation mediated by the cGAS-STING pathway and regulates the transcriptional activity of IFN-beta.  Mechanistically, suppresses the phosphorylation of host key adapter protein TBK1 and degrades host IRF3 in the cyltoplasm.
What are the official names of this protein?
Minor capsid protein M1249L, pM1249L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus M1249L family.
What are the subcellular locations of this protein?
Virion.
Protein: ATPB_RHOJR
Sequence: MTAAVTENNGAGSGSSVAGRVVRVIGPVVDVEFPRGAIPELFNALHAEITLPSVAKTLTLEVAQHLGDNLVRTVSMQPTDGLIRGTSVSDTGKPISVPVGDVVKGHVFNALGDCLDAPGTGRDGEQWGIHRKPPAFDQLEGKTEILETGIKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLHLEMEEMGVLQDTALVFGQMDEPPGTRMRVALSALTMAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSLQAIYVPADDYTDPAPATTFAHLDATTELSRPISQMGIYPAVDPLTSTSRILEPGIVGAEHFRVANEVKRILQKYKELQDIIAILGMDELQEEDKVLVGRARRLQKFLGQNFIVAEKFTGEPGSVVPLRDTIEAFDRICKGEFDHLPEQAFNSCGGLDDVEAAAKKIAGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: EMAL5_RAT
Sequence: MAARSAPSCHLRLEWVYGYRGHQCRNNLYYTAAKEIVYFVAGVGVVYSPREHRQKFYRGHSDDIISLALHPERVLVATGQVGKEPYICVWDSYTVQTVSVLKDVHTHGIACLAFDLDGQRLVSVGLDSKNAVCVWDWKRGKMLSMAPGHTDRIFDISWDLYQPNKLVSCGVKHIKFWSLCGNALTPKRGVFGKTGDLQTILCLACARDELTYSGALNGDIYVWKGINLIRTIQGAHTAGIFSMNACEEGFATGGRDGCIRLWDLTFKPITVIDLRETEQGYKGLSVRSVCWRGDHILVGTQDSEIFEIVVHERNKPFLIMQGHCEGELWALAVHPTKPLAVTGSDDRSVRIWSLVDHALIARCNMDEPIRCAAVNADGVHLALGMKDGSLTVLRVRDMTEVVHIKDRKEAIHELKYSPDGTYLAVGCNDSSVDIYGVAQRYKKVGECVGSLSFITHLDWSSDSKYLQTNDGSGKRLLYKMPGGKEVTSKEEVKGMHWASWTCVAGLEVNGIWPKYSDINDINSVDGNYVGQVLVTADDYGVVKLFRYPCLRKGAKFRKYIGHSAHVTNVRWSHDYQWVISIGGADHSVFQWKFIPERKLKDALHIAPQESLTESNSDESDSDLSDVPELDSEIEQETQLTYHRQVYKEDLPQLKEQCKEKQKSATSKRRERAPGNSIRLHFIHGYRGYDCRSNLFYTQIGEIVYHVAAVGVIYNRQQNTQRFYLGHDDDILCLAIHPLKDYVATGQVGRDPSIHVWDTETIKPLSILKGYHQYGICAVDFSADGKRLASVGIDDSHTIVLWDWKKGEKLSVARGSKDKIFVVKMNPYVPDKLITAGIKHMKFWRRAGGGLIGRKGYVGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIWRDVFLVKTVKAHDGPVFSMHALEKGFVTGGKDGVVALWDDSFERCLKTYAIKRADLAPGSKGLLLEDNPSIRAISLGHGHILVGTKNGEILEVDKSGPVTLLVQGHMEGEVWGLATHPYLPICATVSDDKTLRIWDLSPSHCMLAVRKLKKGGRCCCFSPDGKALAVGLNDGSFLMANADTLEDLVSFHHRKDVISDIQFSPGSGKYLAVASHDSFVDIYNVTSSKRVGVCKGATSYITHIDWDSRGKLLQVNTGAKEQLFFEAPRGKKQTIPSVEVEKISWATWTSVLGLCCEGIWPIIGEVTDVTASCLTSDKMVLATGDDLGFVKLFRYPAKGKFGKFKKYVAHSTHVTNVRWTYDDSMLVTLGGADMSLMVWTSEVERHREKKNCDSEESDTDSEEDGGYDSDVTRENEISYTIRALSTNIRPMFGVKPHLQQKEPSVDERQGVVRGSRPPVSRAPPQPEKLQSNNVGKKKRPIEDLVLELAFGYRGRDCRNNVHYLNDGDDIIYHTASVGILHNVATGTQSFYQEHNDDILCLTVNQHPKFINIVATGQVGDSADMSATAPSVHIWDAVNKQTLSILRCSHSKGVCSVSFSATGKLLLSVGLDPEHTVTIWRWQEGAKIASRGGHNQRIFVAEFRPDSDTQFVSVGIKHVKFWTLAGRALLSKKGLLSTLEDARMQTMLAVAFGANNLTFTGTISGDVCVWKDHILCRVVARAHNGPVFAMYTTLRDGLIVTGGKERPSKEGGAVKLWDQELRRCRAFRLETGQVTDCVRSVCRGKGKILVGTRNSEIIEVGEKNAACNILVNGHVDGPIWGLATHPSRDFFLSAAEDGTVRLWDIADKKMLNKVNLGHAARTVCYSPEGDMVAIGMKNGEFIILLVSSLKIWGKKRDRRCAIHDIRFSPDSRYLAVGSSENSVDFYDLTLGPTLNRISYCKDIPSFVIQMDFSADSRHLQVSSGCYKRHVYEVPSGKHLVDHAAIDRITWATWTSILGDEVMGIWSRHAEKADVTCACVSHSGISLVTGDDFGMVKLYDFPCPEKFAKHKRFLGHSPHVTNIRFTSGDRHVVSAGGDDCSVFVWKCVHTPH
What is the function of this protein?
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
What are the official names of this protein?
Echinoderm microtubule-associated protein-like 5, EMAP-5, EMAP-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EMAP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DNLJ_RHIWR
Sequence: MTTESQAAERLAFLAAEIARHNALYHGEDAPEISDADYDALMRENAALEAEYPHLVRADSPSKLVGAAPSGHLAKVAHAQPMLSLDNAFADEDVVDFVGRVRRYLSLGAEEPVALTAEPKIDGLSCSLRYEKGVLVLAATRGDGTTGEDVTANVRTIDDIPERLRGGDLLSSPPDVFEIRGEVYMAKADFAALNARLLAEAEDPAKARQFANPRNAAAGSLRQKDPGVTASRPLRFLAHGWGEVSALPADTQKGVMDAIAAWGLPVSDDFVRVDGAAQALSHYRAIEAKRADLPFDIDGVVYKVDRLDWQKRLGFVARAPRWAIAHKFPAEKAQTLLKDIDIQVGRTGKLTPVARLEPVTVGGVVVTNATLHNADEIGRLDVHPGDRVVVQRAGDVIPQIVENLSRDETRDPWPFPQTCPECGSAAEREPGEVDYRCTGGLICPAQRVERLRHFVSRHALDIEGLGLTHIESFFRDGLVQSPADIFRLTKDILLTRERWAEVSAGNLIAAIDAKRHPPLDRFLFALGIRHVGEVTARDLARRYRSWEGLKAMIDRTIEARDAAVQAIGETDEKFAARTAKELAAIVETPGVGPEVALALVDFFAEPHNADAVADLLSQLQPADVIHETRASEVSGKTVVFTGTLETMSRDEAKAQAEALGAKVAGSVSAKTDLVVAGPGAGSKLKKASDLGIAVTDEAGWAKIVADAQ
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: LPXA_ECO57
Sequence: MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMAAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HARB_PYRHO
Sequence: MAELPIAPVDRLIRKAGAQRVSEKAAKLLAEHLEEKALEIARKAVDLAKHAGRKTVKVEDIKLAIRS
What is the function of this protein?
Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils.  Increases the resistance of DNA to thermal denaturation (By similarity).
What are the official names of this protein?
Archaeal histone B, Archaeal histone A2.
What is the protein family that this protein belongs to?
Belongs to the archaeal histone HMF family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: SAX1_CAEEL
Sequence: MGEIAPEMEISQYTKDKASCTRISIESYYSKRVTQCAERENRLKKLEEDISARGLSDEEKEEKRKIHHSKETDYLRLKRTRLTVNDFESLKVIGRGAFGEVRLVQKHDTGHIYAMKILRKSEMVEKEQTAHVRAERDILSEADCDWVVKMYYSFQDYSNLYLVMEFLPGGDMMTLLIKKDTLTEEATQFYIAEAALAIQFIHSLGFIHRDIKPDNLLLDARGHVKLSDFGLCTGLKKFHRTDHYRNWPSTLPPDFISKPFESKRKAETWKRNRRAYAYSTVGTPDYIAPEVFQPNGYTKSCDWWSLGVIMYEMLIGYPPFCSELPQETYRKVINWQQTLVFPSDVPISIEAKATIKRFCCEAERRLGNHGGLDEIKQCPFVKRIDWNHIRERPPPIRVTVKSIDDTSNFDDFPDEDLTWPTSTLIRPEEQPGRRGEFVDFTYKRFDGLTQKMRYSDLKKFQQAKKNKKGGQQGTSD
What is the function of this protein?
Acts with sax-2 to restrict the growth of both primary and secondary neurites.  Regulates mechanosensory tiling by controlling the termination point of sensory dendrites.
What are the official names of this protein?
Serine/threonine-protein kinase sax-1, NDR protein kinase, Sensory axon guidance protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YGGL_ECOLI
Sequence: MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDDFINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLDEVRTSELFDVWWD
What are the official names of this protein?
Uncharacterized protein YggL.
What is the protein family that this protein belongs to?
To H.influenzae HI_0341.
Protein: ALR_STRP3
Sequence: MISSFHRPTVARVNLQAIKENVASVQKHIPLGVKTYAVVKADAYGHGAVQVSKALLPQVDGYCVSNLDEALQLRQAGIDKEILILGVLLPNELELAVANAITVTIASLDWIALARLEKKECQGLKVHVKVDSGMGRIGLRSSKEVNLLIDSLKELGADVEGIFTHFATADEADDTKFNQQLQFFKKLIAGLEDKPRLVHASNSATSIWHSDTIFNAVRLGIVSYGLNPSGSDLSLPFPLQEALSLESSLVHVKMISAGDTVGYGATYTAKKSEYVGTVPIGYADGWTRNMQGFSVLVDGQFCEIIGRVSMDQLTIRLSKAYPLGTKVTLIGSNQQKNISTTDIANYRNTINYEVLCLLSDRIPRIY
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: CALM_PATSP
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGDGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin, CaM.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: PRM3_RAT
Sequence: MGSRCAKLSTGHGPAQNTGHSRGHESSMKKLVACVSQDNFSLSSEGEEEEEDEEDEEEEDDDEEDEEEEQIPVKGKLLLLEPEKQDGAEDAVAQPSPEPKQKHS
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Protamine-3, Sperm protamine P3.
What is the protein family that this protein belongs to?
Belongs to the protamine P3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DESM_BOVIN
Sequence: MSQAYSSSQRVSSYRRTFGGAPSFPLGSPLSSPVFPRAGFGTKGSSSSVTSRVYQVSRTSGGAGGLGALRASRLGSTRVPSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAEIYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTFSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL
What is the function of this protein?
Muscle-specific type III intermediate filament essential for proper muscular structure and function.  Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity.  In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.  May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.  Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult.  Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin.
What are the official names of this protein?
Desmin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm. Cell membrane, sarcolemma. Nucleus. Note=Localizes in the intercalated disks which occur at the Z line of cardiomyocytes. Localizes in the nucleus exclusively in differentiating cardiac progenitor cells and premature cardiomyocytes.
Protein: Y2080_LACP3
Sequence: MKFIIAPAKKMIRAQDDFPVQSQPKYRAQAGELLLLMQQLTFSEAQALWHTSDKLTQTAYNQLQQSDLTRQQSPAIFSYSGIQYQYMAPDLLDDAGLVYIQQHLRILSGLYGILRPFDGVVPYRLEMQNHLRLPHHRNLYDFWGNRLYQALARMPGPIINLASDEYAKAIRPYLQAKDQFIDVRFAHRVNGQLKTRATYAKMARGEMIRFAASHRLTKAADLKNFDSPTYRFDSHLSTATQLVFIAK
What are the official names of this protein?
UPF0246 protein LSEI_2080.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: RS5_CHRVO
Sequence: MAKHEMEDRGDGLVEKMISVNRVTKVVKGGRIMAFSALTVVGDGDGGIGMGKGRSKEVPVAVQKAMEQARHNMMKIKLYNGTVKHTVEGRHGATRVLIQPAKDGTGVKAGGPMRAIFDAMGIHNVSAKIHGSTNPYNVVRATLDGLSKINTPAQIAAKRGLSIEDILGVGHE
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: Y4HP_SINFN
Sequence: MISKPVDLPVDVVGAYLALRGEHEALQAKHAIAVAEAANAQAMLSDNEALIVALELKIEKLRRELRGQRSERTARLLDQLELQLEELVAAATEDEVAAQAASARTSSVRSFTRKRPVRKPWPDDIERERVVIEPPTTCTCCGGSRLSKLGEDVTETLEEIPRRFKVIETVREKFTCRDCEAISQTPAPFHATPRGFIGPNLLATILFDKFGMHSPLNRQSARFKCEGIDLSTSTLADQVGYATAALMPVFDLIEAHVFAAERLHGDDTTIPIQARDKCTTGRIWTYVCDDRPFGGTAPPAAIYYASSDRRGEHPQKHLAGYGGILQSDCYNGFEPIAVAATKAVPITFAFCHAHARRKFFELADIQKNARDRKRRGKPISPIALEAVKRYDELFEIERQINGLSAEERLAVRQEKSKPLFDDMHEWLTKERAMLSRSSEVIEPIDYMLKRWEGFALFLKDGRVCLTNNAAERALRSVALGRRNWTFAGSQRGADRAAVMLTVITTCRLNDIDPKAWLADVLARIADHPVTRLYELLPWEWKRASAATVMLAA
What are the official names of this protein?
Uncharacterized protein y4hP.
What is the protein family that this protein belongs to?
Belongs to the transposase 25 family.
Protein: EF101_ARATH
Sequence: MYGQCNIESDYALLESITRHLLGGGGENELRLNESTPSSCFTESWGGLPLKENDSEDMLVYGLLKDAFHFDTSSSDLSCLFDFPAVKVEPTENFTAMEEKPKKAIPVTETAVKAKHYRGVRQRPWGKFAAEIRDPAKNGARVWLGTFETAEDAALAYDIAAFRMRGSRALLNFPLRVNSGEPDPVRITSKRSSSSSSSSSSSTSSSENGKLKRRRKAENLTSEVVQVKCEVGDETRVDELLVS
What is the function of this protein?
Acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways.  Involved in disease resistance pathways.
What are the official names of this protein?
Ethylene-responsive transcription factor 2, AtERF2, Ethylene-responsive element-binding factor 2, EREBP-2.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL15_SALPC
Sequence: MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: YNB9_YEAST
Sequence: MLYSRESRTTVLFLALVTSLTVLCHSVDVTTVFTTSTITEITTVTAAPQPQNKAETALNTATNIIQTMQFLFNCAPFKWKGPLKITSCALNFIVLLLTAWGYLLKYLQENKLNSDADMEKMVGLGFGEMVGRIFGKGVGKAFTKMDITQKLVYPFEGSNRQKCLLMTVGENSIVPFHDLSTEICFDQYTLDSLSHHNHGSISILDAGSVSALGFADISSKMPSVSELYTLFGDYTIEVLGGITKLASTLNREDWQGERNGFAVLSRDRPNQTLLSVHMYSSSLL
What are the official names of this protein?
Uncharacterized membrane protein YNL019C.
What is the protein family that this protein belongs to?
To yeast YNL033w.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NCAP_MEASI
Sequence: MATLLRSLALFKRNKDKPPITSGSGGAIRGIKHIIIVPIPGDSSITTRSRLLDRLVRLTGNPDVSGPKLTGALIGILSLFVESPGQLIQRITDDPGVSIRLLEVVQSDQSQSGLTFASRGTNMEDEADQYFSHDDPSSSAQSRFGWFENKEISDIEVQDPEGFNMILGTILAQIWVLLAKAVTAPDTAADSELRRWIKYTQQRRVVGEFRLERKWLDVVRNRIAEDLPLRRFMVALILDIKRTPGNKPRIAEMICDIDTYIVEAGLASFILTIKFGIETMYPALGLHEFAGELSTLESLMNLYQQMGETAPYMVILENSIQNKFSAGSYPLLWSYAMGVGVELENSMGGLNFSRSYFDPAYFRLGQEMVRRSAGKVSSTLASELGITAEDARLVSEIAMHTTEDRISRAVGPRQAQVSFLHGDQSENEPPRWGGKEDMRVKQSRGEARESYRETGPSRASDARAAHLPTDTPLDIDTASESSQDPQDSRRSAEALLRLQAMAGISEEQGSDTDTPRVYNDRDLLD
What is the function of this protein?
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure with either 12. 35 or 11. 64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases.  N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response.  Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CNTN5_CHICK
Sequence: MMWLSWKLFLFLSLIGCLSESVDYGPVFVQEPDDVIFPTDSEEKKVSLNCQAHGSPTPTYRWLRNGTEIDVESDYRYSLIEGSLIISNPNEMKDSGQYQCLTTNMFGSILSREAVLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPPLHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVTNARVLSPPTPLTLRNDGVMGEYEPKIEVHFPYTVTAARGTTVKMECFALGNPVPTISWKKVNGHNPSKARLRKSQAVLEIPNVQLEDAGMYECKAENSRGRNVFRGQLQVYTYPQWVEKLNDTELDSGEQLRWECKATGKPRPTYRWLKNGVPLWPQSRIEMINSVLMIRTVNISDAGMYQCLAENKYGTIYASAELKILASAPTFPLNQMRKTIIITKGQEVVIECKPQASPKPTITWKKGDKALRESKRVTILPQGSLRILNASKSDEGRYSCRGVNVFGSAEIVASVSVKEPTRIELTPKKIELTVGESIVLSCKALHDSTLDVTFYWTLNGQPIDFDKEDGHFESIKAQASSADLMIRNILLMHAGRYGCRVQTAADAVSDETELLVRGPPGPPGVVIVEEITDTTATLSWSPGADNHSPISLYNLQARSPFSLGWQTVKTVPDVISGDMESAMAVELNPWVEYEFRVVATNKIGTGDPSAPSRMIRTNEAVPKTPPANVSGRSGRRHELVIAWEPVSEEFQNGEGFGYIVAFRPNGTRGWKEKMVTSSDASKFIYRDESVPPLTPFEVKVGVYNNKGDGPFSPIVVICSAEGEPTAAPIDVKATSLSVSEILVAWKHIKESLGRPQGFEIGYWKDMEQEEAAEKVKTAGNESSLLLTGLEGNTLYHLTVRAYNAAGYGPPSTAVRVATKKSPPSQAPSNVMWIQDGSHVSLGWEPVRPLANESEVMGYKVLLRQEGQSNSQVIETQKTSAVVILPDVGVYIIEVCAVSEGGDGTASPQIRVPSYAGGKVTSAQSTLHMFSTSSSSVTLLLVLMVPSTSW
What is the function of this protein?
Contactins mediate cell surface interactions during nervous system development.  May contribute to the formation of somatotopic maps of cerebellar afferents during the development of the nervous system.
What are the official names of this protein?
Contactin-5, F11 axonin-1-related protein 2, FAR-2.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. Contactin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: YQC1_SCHPO
Sequence: MSAASSAIPKRSDPRLLDQKKSAKSTLPKNTPENGVSTVKNLQHVPCKFFRNGTCTAGENCPFSHSLETERPICKYFLKGNCKFGPKCALSHALPGNTNLPNGTSTNTMASMAANGGASSVASKQMGANQISPSLSSKTMKNPADKANNTTATDVRGNTATSPYFPFSRSPGRHSGNSTINGMMTTPNFLSSGVNSRSVDEFNNSSSGFPSSLNGIPIASPPLATSPTSFSLASSASSTNLGGSKGLLFQQMTSENNRDYFSRRPTLLNTYGNRCSSTDTLSSLSRLTSQDPLKASLPLQSPPLAPKTGVSLSRPRLTLDQSLGNLSLGSGINQRRQVPRSNSYAGAFPSVVSASLPTKVDLNHQMDVSDEEQRFLSTPLGSFDESILGSSPINRLSSSFKQYTSSLKSPGLSTRTSSTMNSLNSSRFGAYFSKSRYVEGSGSMSTTPLATSVNNSYKLPSGFSVREEAVFSSPTTEGSRPVSLARLKSEPIFRSDTASPETIAGLGDTKNDPVVSTNNSVSRITVANSSPPWNSTVEEETPFQMDD
What are the official names of this protein?
Uncharacterized protein C1739.01.
Protein: PROW_SALTY
Sequence: MADQTNPWDTAQVADTTTQTADAWGTPAGVATDGGSTDWLNSAPAPAPEHFSLLDPFHKTLIPLDSWVTEGIDWVVTHFRPLFQGIRVPVDYILNGFQQLLLGMPAPVAIILFALIAWQVSGVGMGIATLISLIAIGAIGAWSQAMITLALVLTALLFCVVIGLPMGIWLARSPRAAKIVRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSRGNRRWYTTGPVGLITRPFVK
What is the function of this protein?
Part of the ProU ABC transporter complex involved in glycine betaine and proline betaine uptake.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glycine betaine/proline betaine transport system permease protein ProW.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CORIN_RAT
Sequence: MGRVSFNVRVSSVRRARCSCPGRCYLSCRVPPTTALHALNGFGRAGVLGETAGGTVGLGPSGTRGFLSGSKFQASGSLKDCFGAPPAPDVLRADSSVGEGCPQKLVTANLLRFLLLVLIPCICALIVLLAILLSFVGTLKKVYFKSNDSEPLVTDGEVRVPGVIHVNRYENTGAPSMPPSQSIPAWTPRAPSLEDQSHGNTSTCVNITHRQCQILPYHSTLAPLLPIVKNMDTEKFLKFFTYLHRLGCYQHILLFGCSLAFPKCIVDGDDRHGLLPCRSFCEAAKEGCESVLGMVNSSWPDSLRCSQFRYHTENNSDASRICFSLQQEHGKQSLCGGGESFLCTSGLCISKKLQCNGYNDCDDWSDEAHCNCSEDLFHCGTGKCLHHSLVCDGYDDCGDLSDEQNCDCNLTKEHRCGDGRCIAAEWVCDGDHDCVDKSDEVNCSCPSQGLVECRSGQCIPSTFQCDGDEDCKDGSDEENCSDRPTPCPGGDRGCLDSSCVESCAGSSLCDSDSSLSNCSHCEPITLELCMNLPYNLTHYPNYLGHRTQKEASISWESALFPALVQTNCYKYLMFFACTILVPKCDVNTGQRVPPCRLLCEHSKERCESVLGIVGLQWPEDTDCSQFPEQSSDNQTCLLPNEDVEECSPSHFKCRSGRCVLGSRRCDGQADCDDDSDEENCGCKERDLWECPLNKQCLKHTLICDGFPDCSDSMDEKNCSFCQDDELECANHECVPRDLWCDGWTDCSDSSDEWGCVTLSKNGNSSSFLTVHRSARDHHVCADGWQETLSQLACRQMGLGEPSVTELVQGQEGQQWLRLHSSWENLNGSTLQELLVHRRSCPSGSEISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSLQSEPSGHICGCVLIAKKWVLTVAHCFEGREDADVWKVVFGINNLDHPSGFMQTRFVKTILLHPRYSRAVVDYDISVVELSDDINETSYVRPVCLPSPREFLEPDTYCYITGWGHMGNKMPFKLQEGEVRIIPLEQCQSYFDMKTITNRMICAGYESGTVDSCMIDSGGPLVCERPGGQWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVDWIERQIYIQTFLQKKSQG
What is the function of this protein?
Serine-type endopeptidase involved in atrial natriuretic peptide (NPPA) processing (PubMed:17660514).  Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation (By similarity).  Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus (By similarity).  Also acts as a regulator of sodium reabsorption in kidney (PubMed:20613715).  May also process pro-NPPB the B-type natriuretic peptide (By similarity).
What are the official names of this protein?
Atrial natriuretic peptide-converting enzyme, Corin, Pro-ANP-converting enzyme.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Cytoplasmic vesicle. SUBCELLULAR LOCATION: [Atrial natriuretic peptide-converting enzyme, 180 kDa soluble fragment]: Secreted. Note=Soluble form produced following cleavage by ADAM10.