PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_ILLOL
Sequence: MLRDGNEGMSTIPGSSQIQFEGFCKFIDQGLAEELHKFPKMEDTDQEMEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWRAGRDMRKQTVFIGNIPLMNSLGTSLVNGIYRIVVNQILQSPGIYYRSELDHNGISVYTGTIISDWGGRSELEIDRKARIWARVSRKQKISILVPSSAMGSNLRDILDNVCYPEIFLSFPNDKEKKKIGSKENAVLEFYQQFACVGGDPVFSESLCKELQKKFFQQRCELGRIGRRNMNQRLNLDIPQNSTFLLPRDVLAAADHLIGMKFGMGTLDDLNHLKNKRIRSVADLLQDQFGLALVRLENVVRGTICGAIRHKLIPTPHNLVTSTPLTTTYESFFGLHPLSQVLDRTNPLTQIVHGRKWSYLGPGGLTGRTASFRIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGDWGSIESPFYEISERLKEEQMVYLSPRRDEYYMVAAGNSLALNRGIQEEQVVPARYRQEFLTIAWEQIHLRSIYPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSHSEKCIVGTGLERQAALDSGGSAIAEHEGKITYTDTEKIVLSGNGDTISIPLVMYQRSNKNTCMHQKPQVHRGKCVKKGQILADGAAIIGGELALGKNILVAYMPWEGYNSEDAVLISERLVYGDIYTSFHIRKYEIQTHVTSQGPERITNEIPHLEAHLLRNLDKNGIVMLGSWVETGDILVGKLTPQTAKESSYAPEDRLLRAILGIQVSTAKETCLKLPIGGRGRVIDVRWIQKKRGSSSNPETIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVFNPLGIPSRMNVGQMFECSIGLAGNLLNRHYRIIPFDERYEQEASRKLVFPELYKASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKSYMMKLIHQVDDKIHGRSSGHYALVTQQPLRGRAKHGGQRVGEMEVWALEGFGVAHISQEMLTYKSDHIRARQEVLGTTIIGGTIPNPDGAPESFRLLVRELRSLALELNHFLVSEKSFQINRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NGFV_AGKCO
Sequence: FLIGIWAAPKSEDNVPLGSPATSDLSDTSCAKTHEALKTSRNIDQHYPAPKKAEDQEFGSAANIIVDPKLFQKRRFQSPRVLFSTQPPPLSRDEQNVDNANSLNRNIRAKREDHPVHNRGEYSVCDSVNVWVANKTTATDIRGNVVTVMVDVNINNNVYKQYFFETKCRNPNPVPTGCRGIDARHWNSYC
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons as well as basal forebrain cholinergic neurons in the brain.  Its relevance in the snake venom is not clear.  However, it has been shown to inhibit metalloproteinase-dependent proteolysis of platelet glycoprotein Ib alpha, suggesting a metalloproteinase inhibition to prevent metalloprotease autodigestion and/or protection against prey proteases (By similarity).  Binds a lipid between the two protein chains in the homodimer.  The lipid-bound form promotes histamine relase from mouse mast cells, contrary to the lipid-free form (By similarity).
What are the official names of this protein?
Venom nerve growth factor, v-NGF, vNGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS18_BRASO
Sequence: MAEAPARRPFFRRRKTCPFSGPNAPKIDYKDSKLLMRYVSERGKIVPSRITAVSAKKQRELARAIKRARFLGLLPYVIR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RNBR_BOVIN
Sequence: MALKSLVLLSLLVLVLLLVQVQPSLGKESAAAKFRRQHMDSGSSSSSNPNYCNQMMKRRRMTHGRCKPVNTFVHESLDDVKAVCSQKNITCKNGHPNCYQSKSTMSITDCRETGSSKYPNCAYKTSQKQKYITVACEGNPYVPVHFDGAVLLPATPVPSLPPPHRLL
What are the official names of this protein?
Brain ribonuclease, BRB.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: PRGR_RABIT
Sequence: MTELKAKEPRAPHVAGGAPSPTEVGSQLLGRPDPGPFQGSQTSEASSVVSAIPISLDGLLFPRPCQGQNPPDGKTQDPPSLSDVEGAFPGVEAPEGAGDSSSRPPEKDSGLLDSVLDTLLAPSGPGQSHASPATCEAISPWCLFGPDLPEDPRAAPATKGVLAPLMSRPEDKAGDSSGTAAAHKVLPRGLSPSRQLLLPSSGSPHWPAVKPSPQPAAVQVDEEDSSESEGTVGPLLKGQPRALGGTAAGGGAAPVASGAAAGGVALVPKEDSRFSAPRVSLAEQDAPVAPGRSPLATSVVDFIHVPILPLNHAFLATRTRQLLEGESYDGGAAAASPFVPQRGSPSASSTPVAGGDFPDCTYPPDAEPKDDAFPLYGDFQPPALKIKEEEEAAEAAARSPRTYLVAGANPAAFPDFQLAAPPPPSLPPRVPSSRPGEAAVAASPGSASVSSSSSSGSTLECILYKAEGAPPQQGPFAPLPCKPPGAGACLLPRDGLPSTSASGAAAGAAPALYPTLGLNGLPQLGYQAAVLKEGLPQVYTPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVALPQPVGIPNESQRITFSPSQEIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQSQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: RECR_RICAH
Sequence: MNKTNDHEIDQLIYLFSKLPGLGSRSARRIVLYLLQDKDVRLKSLINNLVEIDKKIVKCKICGNMDTESICSICSSKYRDKSVIAVVETVAELWAMERSGNFKGLYHVLGHNLSAASRQNPSILRLPELLKRCFAENIKEVIIATNSTLEGQTTAYFITEYLKEHPAKISRLASGIPIGGELDYLDEGTLSAAINLRQPFE
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MATK_VIGMU
Sequence: MEQYKAYLELHRSRYQDILYPLFFRESIYGLAYRHESFFIENVDYNNNFSLLIVKRLSTRMYQQTHFILFVNDSKKNTFVGYNYHFYSQIILEGFGIVVEILFSLQLFSSSFRGLEIVKSYTNLQSIHSIFPFFEDKLIYLNHKSDIRIPYPIHLEILVQILRYSIKDVSFFHLIRLFFYYYSNWNSLFPPKKWIFTFFSKRNRRIFLFLYNLYVWEYESIFLFLRNKSSQLQLKHFRVFFERIFFYEKIKHLVKVSTKNCSYTLFFFKDTFIHYVRYQGKSILVLKNTPFLINKWKYYFIYLWQCHFDIWAGLETIYINELSQYSFHFLGYFLSIPLNLSVVRSQMLQNSFLIQIVIKKLDTIVPIIPLMRSLAKTKFCNVMGHPISKPVWANLSDFDILDRFLRICRNFSHYYNGSAKKKSFYQIKYILRFSCIKTLARKHKSTVRIYLKKLSSEKLLEEFFTEEDLFSLIFPRTSLTLRRFYRGRIWYLDILFRNDFVNYL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GVPJ_PSEGP
Sequence: MSQALRPQAIKTSTTGSSLADILERVLDKGIVIAGDITVSVGSVELLSIRIRLLVASVDKAKEIGINWWESDPYLSSRTQELLASNQQLLERVNLLERELAATKATGVIKKGVLGTPFFIWFYDLV
What is the function of this protein?
Gas vesicles are small, hollow, gas filled protein structures that are found in several microbial planktonic microorganisms.  They allow the positioning of the organism at the favorable depth for growth.  This protein could be important for the shape determination of the gas vesicle.
What are the official names of this protein?
Gas vesicle protein GvpJ.
What is the protein family that this protein belongs to?
Belongs to the gas vesicle protein type A family.
What are the subcellular locations of this protein?
Vacuole, gas vesicle.
Protein: OCCQ_AGRT4
Sequence: MDYSQLMGFGPDGWGYDMLRATAMTMAVAFSGFTIGLVFGCLGAAASLSSSGALQAAASGYTTALRGIPDLLVIYLFYFGSSSVISNVASLFGSSGFVGASTFLIGALAIGVVSGAYQTQVLRGAVLALNKGEIEAGRAYGMGALLLFRRIVLPQAARYALPGVGNVWQLVLKESALISVIGLVELMRQAQVGSGSTRQPFSFYLTAAALYLLITFVSGQVFRLAETRSMRGLQRGV
What is the function of this protein?
Component of the octopine active transport system probably consisting of four subunits: Q, M, P and T.
What are the official names of this protein?
Octopine transport system permease protein OccQ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KUP_YERPN
Sequence: MSTEHKQYLSAVTLAAIGVVYGDIGTSPLYTLRECFSGHYGFDVRPDVVFGFLSLIFWMLILVVSVKYLTYVMRADNAGEGGILTLMSLAGRNTSSRATSILVVLGLIGGSFFYGEVVITPAISVMSAIEGLEIAAPALDPYIVPCSIAVLTLLFVIQKHGTGSVGKLFAPVMLVWFLTLALLGLRSIIANPEVLAALNPKWAISFFVEYKSVSFFALGAVVLAITGVEALYADMGHFGKFPIRLAWFTVVLPSLVLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLILATLATVIASQAVISGVFSLTRQAVRLGYLPPMRIIHTSEMESGQIYIPVINWTLYLAVVLVIIGFERSSNLAAAYGIAVTGTMVITSILFCTVAWKNWHWNRFLVVFLLMVLLIIDIPMFSANVLKLFSGGWLPLSLGLVMFIIMTTWKSERFSLLRRMHEHSNSLEAMIASLEKSPPVRVPGTAVYMSRAMNVIPFALLHNLKHNKVLHERVVLLTMRTDDVPYVHNVERVTIEQLSPTFWRVVARYGWRETPNVAEIFHRCGLEGLSCQMMETSFFMSHESLILTKRPWHLFLRGKLFIALSRNALRAPDQFEIPPNRVIELGTQVEI
What is the function of this protein?
Responsible for the low-affinity transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Low affinity potassium transport system protein Kup, Kup system potassium uptake protein.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISPG_SYNY3
Sequence: MVTASLPTPVQPEFDTTIHRRKTRPVPVGAVTVGGGHPVVVQSMINEDTLDVDGSVAGIRRLHEIGCEIVRVTVPSMAHAKALADIKQKLQATYQAVPLVADVHHNGMKIALEVAKHVDKVRINPGLYVFEKPDAQREGYSDQEFAEIGEKIRETLEPLVISLRDQGKSMRIGVNHGSLSERMLFTYGDTPEGMVQSALEFIKICESLDFRNLVVSMKASRVPVMLAAYRLMVKRMDELGMDYPLHLGVTEAGDGEYGRIKSTAGIATLLADGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLEDVLHEVREATKHLTGLDIAVMGCIVNGPGEMADADYGYVGKQAGYIALYRGREEIKRVPETDGVQELINLIKADGRWVDP
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: CERK1_HUMAN
Sequence: MGATGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGADACSVPVSEIIAVEETDVHGKHQGSGKWQKMEKPYAFTVHCVKRARRHRWKWAQVTFWCPEEQLCHLWLQTLREMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETLYEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRSAGVDQNHPRAVLVPSSLRIGIIPAGSTDCVCYSTVGTSDAETSALHIVVGDSLAMDVSSVHHNSTLLRYSVSLLGYGFYGDIIKDSEKKRWLGLARYDFSGLKTFLSHHCYEGTVSFLPAQHTVGSPRDRKPCRAGCFVCRQSKQQLEEEQKKALYGLEAAEDVEEWQVVCGKFLAINATNMSCACRRSPRGLSPAAHLGDGSSDLILIRKCSRFNFLRFLIRHTNQQDQFDFTFVEVYRVKKFQFTSKHMEDEDSDLKEGGKKRFGHICSSHPSCCCTVSNSSWNCDGEVLHSPAIEVRVHCQLVRLFARGIEENPKPDSHS
What is the function of this protein?
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate (PubMed:11956206, PubMed:16269826, PubMed:19168031).  Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines (PubMed:11956206, PubMed:16269826, PubMed:19168031).  Shows a greater preference for D-erythro isomer of ceramides (PubMed:16269826).  Binds phosphoinositides (PubMed:19168031).
What are the official names of this protein?
Ceramide kinase, hCERK, Acylsphingosine kinase, Lipid kinase 4, LK4.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: AROA_PROMT
Sequence: MNAPTKDQSLRNLQKGGELCGKVKVPGDKSISHRALLFGAIAKGKTLIEGLLPAEDPLSTAECLRSMGVKISPIKKGDIIEIEGVGLNGLQEPQDILNCGNSGTTMRLIMGLLAGQKDHHFILTGDKSLRNRPMKRVGQPLKMMGAKVFGRCGGNLAPLSIIGNKLRGAVIGTPVASAQIKSAILLAALNAEGSTTVIEPARSRDHSERMLKAFGANLEVGGEMGRHITVSPGKDLKGQSIIVPGDISSAAFWLIAGSIIPGSELVVENVGLNPTRTGILDVLEEMEANINVINKRDVAGEPVGDIEVFYKENLKPFKIDGEIMPRLVDEIPILSVGACFCNGISQIKGASELRVKETDRLAVMARQLKRMGASVDEHQDGLTIYGGKSLEGCELDSEDDHRIAMSLAIASIMANSNSTLRRSEAAAISYPDFWSDLKRLQQKN
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCMA_XANOM
Sequence: MIEPLHTAPPLLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVEHGQIQIDGKTAKRGDRSRFMAYLGHLPGLKADLSTLENLHFLCGLHGRRAKQMPGSALAIVGLAGYEDALVRQLSAGQRKRLALARLWLSPAPLWLLDEPYANLDLDGITLVNRMISAHLRGGGAALVTTHGAYAAPPVRTRMLTLEAAA
What is the function of this protein?
Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Cytochrome c biogenesis ATP-binding export protein CcmA, Heme exporter protein A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS19_XANCP
Sequence: MARSLKKGPFVDHHLAKKVESAAGSKKPIKTWSRRSMILPEMVGITIAVHNGKNHIPVLVNENMVGHKLGEFAVTRTFKGHGGDKKSSR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: YACG_THIDA
Sequence: MTNASKPPVVNCPICGATVKWLAENRWKPFCSERCKLIDLGQWATEKYRVPVEPKPDEGETPDQAERPQ
What is the function of this protein?
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA.  Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
What are the official names of this protein?
DNA gyrase inhibitor YacG.
What is the protein family that this protein belongs to?
Belongs to the DNA gyrase inhibitor YacG family.
Protein: ARLY_CITK8
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTADEQLQLEEALSALLEEVRVNPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVTELLSANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTAMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGETVVEAIRQGKPLEDLSLADLQKFSAVIGDDVYPILSLQSCLDKRAAKGGVSPQQVAQAIDYAKARLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPS2_MIMIV
Sequence: MAGGIIQLAVYGTQDIFLTGSPQITFFKTIYRRHTNFAVESIVQHFIGDINFGQEIVSVVEKMGDLMSRVYLEIDIPKINLVKNSSNWIKDKSTAKNDYDKISNFYGLVYNYISVNTDLARKIKFLLSNNNISLNDISLIVLHNQFNSELDKAYTDLYKYINDTNSTDGFIQSQIPRTFNIINIFKSVYEKNLYIETNNPDEIGSIKKAELLKIINTRLYKQMYDYYIDIYRQYLSKKNIFESFENGTYEENYKFAWVEELGHAIIDYVDIKIGNQVIDKHTGDWFIIFNKLFTKIYQIENYNKMIGNVKELTIFDDKIKKSYKLIIPFQFWFCRNTGLALPLIALRYHEVMFTIKLKELSKVCYVEDNDDIVSMENLQSLYNINLIDAKLYIDYIFLDTIERKRFAQSAHEYLIEVVQYQTFDNIDHSKYNSHLKFSHPTKYIVWFVQPSHYRENPTGKTKCQWNNFGTSPDLTGQPLNNTHLRINSYERTDPNLGVGYYNYVQPYWYFISTPTDGLYVYSFSLKPTEHQPSSTLNLSRIHDFGIYLEFSKELSKIIESNCSSIFFGTYIMSYNILRFMSGMAGLGFQNI
What are the official names of this protein?
Probable capsid protein 2.
What is the protein family that this protein belongs to?
Belongs to the NCLDV major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ISPE_STAAB
Sequence: MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHKRKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGSADAAATLRGLNRLFDIGASLEELAQLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKPPSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEPISVSKHPQIDKLKNNMLKSGADGALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVYLVRLLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: YCEH_ECO57
Sequence: MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVELTLEQLANREDGPFVVRLAREPGKRESRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
What are the official names of this protein?
UPF0502 protein YceH.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: LEUC_SODGM
Sequence: MGKSLYQKLYDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRTVRQPGKTFATMDHNVSTQTKDINACGDMARIQMQELMKNCAEFGVQLYDLNHPYQGIVHVIGPEQGMILPGMTIVCGDSHTATHGAFGALAFGIGTSEIEHVLATQTLKQGRAKTMKVDMTGHASPGITAKDIVLAIISKIGSAGGTGHVVEFSGSAIRALSMEGRMTLCNMAIEMGAKAGLVAPDDTTYAYLQNRQFAPKGDDWHQAVMYWDTLKSDDDARFDKVVTLDAQDIAPQVTWGTNPGQVIAVNQVIPSPESFSDPVERNSAAKALAYMDLQPGIRLTDVTIDKVFIGSCTNSRIEDLRAAAAVARGRRVAAGVQAIVVPGSGPVKAQAEAEGLDRIFLDAGFEWRLPGCSMCLAMNNDSLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVAGRFADIRELN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: ACEK_KLEP7
Sequence: MTRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKQRIHLYDHHVGLVVEQLRCITEGKSTDVDFLLRVKQQYTQLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERPFRTLPRPLAKDFFPERGWSHLLGKVLSDLPLRLPWQNKARDIGYIIASLQEALGEELLATCHLQVANELFYRNKAAWLVGKLVMPMATLPFLLPIHRSEEGELFVDTCLTTHAEASIVFGFARSYFMVYAPLPGALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLHYITRCDEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEMTAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIAPALLALLQAEAGNKLTDLGDRIVISHLYIERRMVPLNLWLEQVNGQALRDAVEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFREIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLLRADYWRALQMRIKNGHVEDVYAYRRKQRFSVRYGADSRPDKAFTPPSGKVRRSA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP3_STAAM
Sequence: MKSLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHLVTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIATDAGREGELVARLILDKVGNKKPIRRLWISSVTKKAIQQGFKNLKDGRQYNDLYYAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYFTLSLTVKGFDFQLESNQRYTNKETLEQMVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQDMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQATMATTYKDQARPLMSKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLEALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKISKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADIIDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAKTFINEMKDFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKVSRKEMKKYMNKNEGLDNNPFKDALKNLNL
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: BTSR_ECO57
Sequence: MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKPIDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRMSGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILRNGLTVPVSRRYLKSLKEAIGL
What is the function of this protein?
Member of the two-component regulatory system BtsS/BtsR.  BtsR regulates expression of btsT by binding to its promoter region.
What are the official names of this protein?
Transcriptional regulatory protein BtsR.
Protein: ASNA_PLAF7
Sequence: MSEDESNSVSCSLSLESDGYSDEEYDTNLNKLIENESLNWIFVGGKGGVGKTTTSCSIAVQLSKRRESVLLLSTDPAHNTSDAFNQKFTNQPTLINSFDNLYCMEIDTNYSENTAFKLNKKEMFDNILPELLHSFPGIDEALCFAELMQSIKNMKYSVIVFDTAPTGHTLRLLAFPDLLKKALGYLINIREKLKGTLNVLKNFTNNEMEFDSLYEKINHLNAMSSSIQANFQNPMKTTFVCVCIPEFLSVYETERLIQELTKKNISCYNIVVNQVVFPLDSPNVNLENCKNLLSQIKNEQIQSYFNDLISKTEELEDVYISRRKLQSKYLTQIKNLYSNDFHIVCMPQLKNEIRGLNNISSFSEMLLQSKDIPIYKDNL
What is the function of this protein?
ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion.  This process is regulated by ATP binding and hydrolysis.  ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins.  ATP hydrolysis is required for insertion.  Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
What are the official names of this protein?
ATPase ASNA1 homolog, Arsenical pump-driving ATPase homolog, Arsenite-stimulated ATPase.
What is the protein family that this protein belongs to?
Belongs to the arsA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: Y1467_SHEB8
Sequence: MQYQVDTHTHTVASSHAYSTIHDYIAVAKQKGIRLFANTDHGPAMADAPHFWHFVNLRVLPRMVDGVGILRGIEANIKNIDGEIDFFGDYLKQLDIVLAGFHEPVYPPSDKATHTEAMINTIKSGKVDIITHPGNPAYPIDIEAVARAAAEYGVALEINNSSFEVSRKGSEANCTAIAKAAKEFGTILVMGSDSHVAFSLGGFARAQAIIDEVAYPPSRLLNRSPSALLTFLAARGHETVADLIPLFSDDEPCC
What are the official names of this protein?
Probable phosphatase Shew185_1467.
What is the protein family that this protein belongs to?
Belongs to the PHP family.