PharMolix/UniProtQA huggingface dataset:
Protein: BAG6_RAT
Sequence: MEPSDSTSTAMEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLIYQGRVLQDDKKLQDYNVGGKVIHLVERAPPQTQLPSGASSGTGSASATHGGGPLPGTRGPGASGHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLLSRMECRGGTQAQASQPPPQTPTVASETVALNSQTSEPVESEAPPREPMESEEMEERPPTQTPELPPSGPAPAGPAPAPETNAPNHPSPAEHVEVLQELQRLQRRLQPFLQRYCEVLGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACAPPRHLHVVRPMSHYTTPMVLQQAAIPIQINVGTTVTMTGNGARPPPAPGAEAASPGSGQASSLPPSSATVDSSTEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGAQPGGVPSAPTGPLGPPGHGQSLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGALQGAGLGTNTSLAQMVSGLVGQLLMQPVLVAQGTPGMAPASASAPATAQAQAPAPAPAPAPAPATASASAGTTNTATTAGPAPGGPAQPPPPQPSAADLQFSQLLGNLLGPAGPGAGGPSLASPTITVAVPGVPAFLQGMTEFLQASQAAPPPPPPPPPPPPAPEQQTTPPPGSPSGGTASPGGLGPESLPPEFFTSVVQGVLSSLLGSLGARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLRSFFHQHYLGGQEPTSSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRIGDPPQALPEEPMEVQGAERTSPEPQREDASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASADAEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAHRAFADDP
What is the function of this protein?
May mediate ricin-induced apoptosis.
What are the official names of this protein?
Large proline-rich protein BAG6, BCL2-associated athanogene 6, HLA-B-associated transcript 3.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Secreted, extracellular exosome. Note=Normally localized in cytosol and nucleus, it can also be released extracellularly, in exosomes, by tumor and myeloid dendritic cells.
Protein: PLYE_DICD3
Sequence: MNNSRMSSVSTQKTTGRSALGTKSALAAIIATTMMVSVASAASLQTTKATEAASTGWATQSGGTTGGAKASSSKIYAVKSISEFKAALNGTDSSPKIIQVTGAIDISGGKAYTSFDDQKARSQISIPSNTTIIGIGNKGKFTNGSLVVKGVSNVILRNLYIETPVDVAPHYEEGDGWNAEWDAVVIDSTDHVWVDHVTISDGSLTDDKYTTKNGEKYVQHDGSLDIKRGSDYVTVSNSRFELHDKTILIGHSDNNGSQDAGKLRVTFHNNLFDRVGERTPRVRFGSVHAYNNVYVGDVNHKAYRYQYSFGIGTSGSLLSESNAFTIDNMKKISGRDKECSVVKAFNGKIFSDKGSIINGASYNLNGCGFGFSAYSAKIPYKYSAQTITTSLANSISSNAGYGKL
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Pectate lyases have been implicated as pathogenicity factors which induce maceration or rotting of plant tissue.  PelE is sufficient to induce these effects under laboratory conditions.
What are the official names of this protein?
Pectate lyase E.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family. PLBC subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPH_CAMJD
Sequence: MIIELAKNYGFCFGVKRAIKKAEQIKDAATIGPLIHNNEEISRLQKNFNVKTLENIKSLSNETKAIIRTHGITKQDLEELRKKDIEIFDATCPFVTKPQQICEQMSKEGYEIVIFGDENHPEVKGVKSYVNTKAYVVLDKKELQNIKLPSKIAVVSQTTKKPEHFMEIVNFLMLKAKEVRVFNTICDATFKNQDAIKELSLKSDVMVVVGGKNSANTKQLFLIAKTNCEDSYLIETEEELKKEWFLDKKHCGISAGASTPDWIIQKVIAKIENFGIN
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase, HMBPP reductase.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: GATA_RHOP5
Sequence: MTDLTSLTLAEARDGLAKKSFTALQLTDAHLAAIEAARVLNAYVLETPEQARAMAKAADERIARGAAGPLEGLPLGIKDLFATQGVRTTACSKILGEFSPPYESTVSAQLWRDGAVLLGKLNNDEFAMGSSNETSCFGPVVNPWRREGSDAKLVPGGSSGGSASAVAAGLCLGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGIVAFASSLDQAGPIARTVRDAAILLRSMAGHDPKDTTSVDRAVPDYEAAIGRSVKGMKIGIPKEYRIDGMPAEIEALWKQGADWLKAAGAELVEVSLPHTKYALPAYYIVAPAEASSNLARYDGVRYGARVNGRNIVEMYENTRAAGFGAEVKRRIMIGTYVLSAGYYDAYYLRAQKVRTLIKRDFEECFAKGVSAILTPATPSAAFGIGEKGGADPVEMYLNDIFTVTVNMAGLPGIAVPAGKDAQGLPLGLQLIGRPFDEDTLFSLGEVIEQAAGRFTPTKWWA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: PDXJ_SALTY
Sequence: MAELLLGVNIDHIATLRNARGTDYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTLHTRMNLEMAVTEEMLAIAVETRPHFCCLVPEKRQEVTTEGGLDVAGQRDKMRDACARLAAAGIQVSLFIDADETQINAAAEVGAPFIEIHTGCYANAETDAEQAKELARIASAATLAARLGLKVNAGHGLTYHNVKAIAALPEMHELNIGHAIIGRAVMTGLKEAVAEMKRLMLEARG
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_STRA3
Sequence: MLYPTPIAKLIDSFSKLPGIGTKTATRLAFYTIGMSDEDVNEFAKNLLAAKRELTYCSVCGNLTDDDPCLICTDKTRDQSVILVVEDSKDVSAMEKIQEYNGLYHVLHGLISPMNGISPDDINLKSLITRLMDGQVTEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RDGC_YERPN
Sequence: MLWFKNLMVYRLSREVSLSADEMEKQLSAFSFTPCGSQDMAKTGWVSPMGSHSDALTHTVNGQIVICARKEEKILPSPVIKQELQDKIERLEGEQHRKLKKTEKDSLKDEVLHSLLPRAFSRFNQTFLWIDTVNDLIMVDAASAKRAEDTLALLRKSLGSLPVVPLTLENPIELTLTEWVRSKTLPAGFALMDEAELKAILEDGGVIRCKKQDLFSDEIAVHIEAGKLVTKLALDWQERIQLVLSDDGSLKRLKFADTLRDQNEDIDREDFAQRFDADFILMTSELAALIKNLIEALGGEAQH
What is the function of this protein?
May be involved in recombination.
What are the official names of this protein?
Recombination-associated protein RdgC.
What is the protein family that this protein belongs to?
Belongs to the RdgC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL19_STRP1
Sequence: MNPLIQSLTEGQLRSDIPNFRPGDTVRVHAKVVEGTRERIQIFEGVVISRKGQGISEMYTVRKISGGIGVERTFPIHTPRVDKIEVIRHGKVRRAKLYYLRALQGKAARIKEIRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PGK1_PIG
Sequence: MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAIPSIKFCLDNGAKSVVLMSHLGRPDGIPMPDKYSLEPVAVELKSLPGKDVLFLKDCVGPEVEKACADPAAGSVILLENLRFHVEEEGKGKDASGSKVKADPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPKKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGSKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKIGQATVASGIPAGWMGLDCGPESSKKYSEAVARAKQIVWNGPVGVFEWEAFAQGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV
What is the function of this protein?
Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate.  In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein).  May play a role in sperm motility.
What are the official names of this protein?
Phosphoglycerate kinase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF2_XANAC
Sequence: MALLPILEFPDPRLRTKAVPVDAAEVTSQAFQTLLDDMFHTMYEAPGIGLAASQVDVHKRFMVIDISDEKNLPQVFVNPEIVSKQGEQLYQEGCLSVPGIYADVSRADAITVRYLDRQGQPQELHADGLLAVCIQHEMDHLDGKLFVDYLSPLKREMVRKKLAKQRKHVA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: TRF3_THEAC
Sequence: MEVEKYDLTLDFDIQKRTFNGTETITADAGDIVLDAVGLQINWMKVNGRDTAFTYDGQTVRAPGDSQPQKIEISFAGKVSDSLSGIYYAGRENGMITTHFEATDARRMFPCVDHPAYKAVFAITVVIDKDYDAISNMPPKRIEVSERKVVEFQDTPRMSTYLLYVGIGKFRYEYEKYRDIDLILASLKDIRSKYPLDMARKSVEFYENYFGIPYALPKMHLISVPEFGAGAMENWGAITFREIYMDIAENSAVTVKRNSANVIAHEIAHQWFGDLVTMKWWNDLWLNESFATFMSYKTMDTLFPEWSFWGDFFVSRTSGALRSDSLKNTHPIEVDVRDPDEISQIFDEISYGKGASILRMIEDYAGYEEFRKGISKYLNDHKFGNAEGSDLWTAIEDVSGKPVKRVMEYWIKNPGYPVIKLKRNGRKITMYQTRFLLNGEEEGRWPVPVNIKKKDGVERILLEDEASIEADGLIKINADSAGFYRVLYDDATFSDVMGHYRDLSPLDRIGLVDDLFAFLLSGHIDPETYRQRIRNFFDDEDHNVITAIVGQMEYLRMLTHAFDDDARAFCRSRMQFLTGKQDENLKIALGRVSRLYVMVDESYAEEMSKLFKDFDSAEPEMRSSIATAYALVTGDLKGLLEKFRSVDRDEDRVRIISAFGKLKSNTDLSTVYGMVEKTEIKKQDMISFFSSALETLPGREFIFANLDRIIRLVIRYFTGNRTASRTVEMMIPVIGLDHPDAEDIVRNIGSKNISMGLAKGIEMLAVNRKLVERIRQTAVK
What is the function of this protein?
Proteases F1, F2 and F3 degrade oligopeptides produced by Tricorn (themselves probably produced by the proteasome), yielding free amino acids.
What are the official names of this protein?
Tricorn protease-interacting factor F3.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPH2_VACCW
Sequence: MEKNLPDIFFFPNCVNVFSYKYSQDEFSNMSKTERDSFSLAVFPVIKHRWHNAHVVKHKGIYKVSTEARGKKVSPPSLGKPAHINLTAKQYIYSEHTISFECYSFLKCITNTEINSFDEYILRGLLEAGNSLQIFSNSVGKRTDTIGVLGNKYPFSKIPLASLTPKAQREIFSAWISHRPVVLTGGTGVGKTSQVPKLLLWFNYLFGGFSTLDKITNFHERPVILSLPRIALVRLHSNTILKSLGFKVLDGSPISLRYGSIPEELINKQPKKYGIVFSTHKLSLTKLFSYGTLIIDEVHEHDQIGDIIIAVARKHHTKIDSMFLMTATLEDDRERLKVFLPNPAFIHIPGDTLFKISEVFIHNKINPSSRMAYIEEEKRNLVTAIQMYTPPDGSSGIVFVASVAQCHEYKSYLEKRLPYDMYIIHGKVLDIDEILEKVYSSPNVSIIISTPYLESSVTIRNVTHIYDMGKVFVPAPFGGSQEFISKSMRDQRKGRVGRVNPGTYVYFYDLSYMKSIQRIDSEFLHNYILYANKFNLTLPEDLFIIPTNLDILWRTKEYIDSFDISTETWNKLLSNYYMKMIEYAKLYVLSPILAEELDNFERTGELTSIVREAILSLNLRIKILNFKHKDDDTYIHFCKILFGVYNGTNATIYYHRPLTGYMNMISDTIFVPVDNN
What is the function of this protein?
NTP-dependent helicase that catalyzes unidirectional unwinding of 3'tailed duplex RNAs and plays an important role during transcription of early mRNAs, presumably by preventing R-loop formation behind the elongating RNA polymerase.  Might also play a role in the export of newly synthesized mRNA chains out of the core into the cytoplasm.  Required for replication and propagation of viral particles.
What are the official names of this protein?
RNA helicase NPH-II, Nucleoside triphosphatase II, NTPase II, Nucleoside triphosphate phosphohydrolase II, NPH II, RNA helicase I8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Virion. Note=Localizes to the virion core.
Protein: ACT1_SCHMA
Sequence: MAEEDVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYMMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMGTAASSSALEKSYELPDGQVITIGNERFRCPEALFQPSFLGMEASGIHETTYNSIMKCDVDIRKDLYSNTVLSGGSTMYPGIADRMQKEISALAPSTMKIKIVAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPGIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: TGT_CHRVO
Sequence: MLKFTVHKTSGGARRGTLELNHGTVETPVFQPVGTYGSVKAMSPVELNDIGAQIILGNTFHLWLRPGLEIVEQFGGLHEFIGWDKPILTDSGGFQVFSLSDMRKLTEEGCTFQSPINGDKLFLSPEISMKIQTVLNSDIVMQLDECTPGQVDHATAQKSLQMSLRWAERSRRAFDDLKNPNALFGIVQGNLYTDLRQESLEGLMQVGFDGIAIGGLSVGEPKPEMYRMLTELKDMLPADKPHYLMGVGTPEDLVHGVANGVDMFDCVMPTRNARNGWIFTQWGDVKIKNARYKDDKKPLDEECACYACRNFSRAYLHHLHRVGEILGARLNTIHNLFYYQELMREMRKAIEEDRFEDFRLEFAAKRARSVN
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RSSA_KOMPG
Sequence: MSLPASFDLTAEDAKLLLAANVHLGAKNCQVHNEPYVYKTRPDGVNVINIGKTWEKIVLAARIIAAIPNPEDVVAVSSRTFGQRAVLKFASHTNGSAIAGRFTPGSFTNYITREFKEPRLIIVTDPRTDSQAIKESSYVNIPIIALTDMDSPSEFVDVAIPCNNKGKHSIGLIWYLLSREVLRLRGVLPNRTEAWSVMPDLYFYRDPEEIEQTAEEEAEAAEGAEFEVEEEEVEQEWQEPAEADWNASAPPADWNDAANAEAF
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_CUPTR
Sequence: MQLVIVAVGHKMPGWIETGFSEYAKRMPPELRIELREVKPETRSSSNNAATVMQREAARIEAVLGSLSKQCRIVALDERGRDFTTVQLAAQLTDWQREGGDVAFLIGGADGLDPALKARASTLIRLSSLTLPHGMVRVLLAEQLYRAWSVTQNHPYHRA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CTRA_BRUA4
Sequence: MRVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARIHAIVRRSKGHAQSVITTGDLVVNLDAKTVEVSGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLDAVSGSQSYIETVWGRGYVLREPDAEMRESA
What is the function of this protein?
Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes.
What are the official names of this protein?
Cell cycle response regulator CtrA.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_LACPL
Sequence: MLKKQPLSPTDVRDSKVYRDWGLTDAEYQLLTDKVLQRLPNETETGLFSGMWSEHCSYKNSKPVLKKFWTQGEQVLEGPGEGAGIIDIGDGQAVVFKAESHNHPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGEPTDAHTKYLISQVVAGIGGYGNCIGIPTIGGDTVFDASYQKNPLVNAMCVGILDQADIQKGQATGIGNAVIYVGAKTGRDGINGASFASAEFNDANETQRSAVQVGDPFMEKLLMEACLEVIHEHRDVLIGIQDMGAAGLVSSSAEMASKAGSGLSLNLDLVPQRETGMTPFELMLSESQERMLLCVKAGAEAEIYQVFEKYGLDAVTIGKVTAGHQYQLFHHGKLVADVPVDALATKAPVYEREKKRPTRLNHQSHHQFMPRLVDATGTLKKMLQQPTIASKASLYGTYDSQVQTNTVVKPGSDAGVIRIRHTDKALAVTTDVNGRYLYLNPRVGGEIAVAEAARNIVASGGQPLGITDCLNYGNPEKPEQFYDLDESAMGIARACQLFNTPVISGNVSLNNESNGEAIYPTPMIGMVGLIKHQKDITTSDFKHAGDAVYVLGTTEADFNGSELQKMLTGTISGELFDFDLVTENRNQRLLLTAIQKGLVASAHDVSEGGLITTIAESCFPQNIGVELASDLPAANFFAETQSRFVISVTPAQQAAFESLMEPYVTYLGRTTATDRLHVQTADQAFDIKVSFAKQLWEGALPCLLK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACADS_PONAB
Sequence: MAAALLARASGPVRRALRPRAWRQLHTIYQSVELPETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVKKMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQKWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTDRALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQTLDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAAMLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEIQRLVIAGHLLRSYRS
What is the function of this protein?
Short-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats.  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA.  Among the different mitochondrial acyl-CoA dehydrogenases, short-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 4 to 6 carbons long primary chains.
What are the official names of this protein?
Short-chain specific acyl-CoA dehydrogenase, mitochondrial, SCAD, Butyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL14_HERAR
Sequence: MIQTESRLEVADNTGAREVMCIKVLGGSKRRYAGIGDVIKVTVKVAAPRGRVKKGEIYNAVVVRTAKGVRRQDGSLVKFDSNAAVLLNAKLEPIGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GLO2_SHEON
Sequence: MLTITAINAFNDNYIWVLQQDTQQAVYVVDPGDVNVVLDYLNAHQLTLAGILITHHHRDHTGGIAALVAYVEQTTGHTLAVYGPQSEAIQGVNIAIEPQITQILHLPFLNSPVQVLSVPGHTAGHIAYLVDGALFCGDTLFSGGCGRLFEGTPAQMCHSLRLLAALPAETRVYCAHEYTLANLKFAQAADPSNAKLKAYNEQATALRAQGKATIPSTIGLERSINPFLRGLTPTIVDSIKQQFCDQDLSNVDELTYFTLLRQWKDIF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: GLPK_SHEB8
Sequence: MQKKYVVALDQGTTSSRAIVFDHDANIVSVSQREFTQLYPNPGWVEHDPMEIWASQSSVLVEVLARAGIHSDEVAAIGITNQRETTVIWEKATGKPIYNAIVWQCRRSSEICEQLKAQGLEEYVRENTGLLLDPYFSGTKIKWILDNVPNARAQAERGELLFGTIDTWLVWKLTEGKVHVTDPTNAARTMLFNIHSLTWDNKLLEALDIPLSLLPEVKPSCSVYGTTRIAGEGSEIQVAGMAGDQQAALFGQLCVEPGMAKNTYGTGCFLLMNTGTKAVRSNHGLLTTVAVGPKGEVNYALEGSVFMGGATIQWLRDELGLIRDASDTEYFASKVADTNGVYLVPAFVGLGAPYWDPNARGALFGLTRGANRNHIIRAALESIAYQSKDLLDAMTKDSGVSLKRLKVDGGAVANDFLMQFQADITDVEVLRPSVCETTALGAAFLAGLAVGFWESVIELEHKACIDKHFIPNIDAETRVRLYAGWQDAVARTRA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: AROD_LISMC
Sequence: MNKVVVKNVTFGEGAPKICVPMVGKTVAALKEEAEMLQTIDLDVVEWRVDFFEDVKDLAKVEAALDEIRTILPETPILFTFRSAKEGGELAVSDEFYFELNETLAGTGKIDLVDVELFNEEADVLRLIETAHKNNVKVVMSNHDFDKTPAKEEIVSRLTRMEALGADLPKIAVMPKSAGDVLTLLDATNTVSEKANQPIITMSMAGTGVISRLAGEVFGSAMTFGAAKKASAPGQIDVNELRHVLDLLHKQF
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: MLPH_BORBU
Sequence: MKIINILFCLFLLMLNGCNSNDNDTLKNNAQQTKSRRKRDLTQKEVTQEKPKSKEELLREKLNDDQKTQLDWLKTALTDAGEFDKFLENNEDKIKSALDHIKSELDKCNGKENGDVQKNTFKQVVQGALKGGIDGFGASNATTTCNGS
What is the function of this protein?
An outer membrane protein that may participate in pathogenesis.  Some human Lyme disease patients have antibodies against this protein (PubMed:10948116).  The Mlp proteins probably undergo intragenic recombination, generating new alleles (Probable).
What are the official names of this protein?
Lipoprotein MlpH.
What is the protein family that this protein belongs to?
Belongs to the Multicopy lipoprotein (Mlp) family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: YEIB_SCHPO
Sequence: MYSRVLSVAAIVTMALAVQAANSTAPYGNTTNSTGTTNGTNGTNTTTSSTATQSSAASITNFSSGAFVIAMIAVACSVMSL
What are the official names of this protein?
Uncharacterized protein C27E2.11c, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: RL14_DESAP
Sequence: MIQVQTVLNVADNTGAKKLMCIRILGSSFRRYASIGDIIVCSCKEAAPGGVVKKGDVVKAVVVRTKKEIGRPDGSYIKFDENAAVVIKDDKSPRGTRIFGPVARELREKDFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MQO_NEIMA
Sequence: MAEATDVVLVGGGIMSATLGVLLKELEPSWEITLIERLEDVALESSNAWNNAGTGHSALCELNYAPLGANGIIDPARALNIAEQFHVSRQFWATLVAEGKLEDNSFINAVPHMSLVMNEDHCSYLQKRYDAFKTQKLFENMEFSTDRNKISDWAPLMMRGRDENQPVAANYSAEGTDVDFGRLTRQMVKYLQGKGVKTEFNRHVEDIKRESDGAWVLKTADTRNPDGQLTLRTRFLFLGAGGGALTLLQKSGIPEGKGYGGFPVSGLFFRNSNPETAEQHNAKVYGQASVGAPPMSVPHLDTRNVDGKRHLMFGPYAGFRSNFLKQGSLMDLPLSIHMDNLYPMLRAGWANMPLTKYLLGELRKTKEERFASLLEYYPEANPDDWELITAGQRVQIIKKDSEKGGVLQFGTEIVAHADGSLAALLGASPGASTAVPLMIRLMHQCFPERTPSWEGRLKELVPGYGIKLNENPERADEIIAYTAKVLDI
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.