PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_SOLUE
Sequence: MRSSPYDRANLIADFDSIRISLASPEKIRSWSHGEVTKPETINYRTFKPERDGLFCARIFGPTQDWECLCGKYKRMKHRGVICDKCGVEVTLARVRRERLGHIELASPCSHVWFFKGLPSRIGHLLDITLRELERVLYFEAYVIVDPGDGTGLSSGEVITDERKRQLDQEFPGKFIAMMGAEGIKELLKKIDVESLSEEIREKMKTEQSQQKKLKHAKRLRVVESFRKSGNKPEWMILDVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKKLIELHAPDVIVRNEKRMLQEAVDALFDNGRRGRVLRGANNRPLKSLSDTLKGKQGRFRQNLLGKRVDYSGRSVIVVGPDLKLHQCGLPKKMALELFKPFIYHRLEQRGHCTTIKQAKELVEQQDPVVWDILEEVIKDHPIMLNRAPTLHRLGIQAFEPVLVEGKAIKIHPLVCTAFNADFDGDQMAVHIPLSPEAQIEASTLMLSANNILSPAHGGPITIPTQDMVLGCYYLTKSRPGAKGEGRTFASTDDVLIALEMGEVETLTPIKLRYTGKVIDLVHAFDTQNILHTEPIEFIKQYMDTTVGRVILNDNLPQDMPYINGLLKKKGLAQLVQYCYLKFGLHVTVHMLDEIKSLGFLYATRAGISIGIDDMVVPSEKAGLVRDAEKEVVLVENQYQDGAITHGERYNKIIEIWSKVTERVSDEMFTAMEEDDRTGRYLNPIYIMADSGARGSKQQIRQLSGMRGLMAKPSGEIIETPITANFREGLNVLQYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIISENDCGTTEGIYVEPIIESGEIIEALRDRIVGRVALEDQKDYEGNVIVGVNQEITEDLAAAIQAAGIERVKIRSVLTCESKRGVCVACYGRNLATGRLVERGEAVGVIAAQSIGEPGTQLTMRTFHIGGTATRINEQSKQDAKSDGFARYIGIQTVRSKVGELIAMNRNGIMAVVDDKGREKERYPAVYGARVLVEDGAPVKSNQVLLEWDPYTFSILTEVSGVVHFKDLIDGLTMQERLDEVTGMSQLVVIDSPDEKRQPMIQVRPEGATGRGSEAKKYLMPTHAHLMVRDGEELHAGDVLAKIPRETTKTKDITGGLPRVVELFEARKPRETAIIAEINGTVKYGEVTKGQRKIYVEGEDGEKREYALPRGVHINVQEGEKVKAGEPLMDGPRDPHDILAVLGEKELQKYLVNEIQEVYRLQGVNINDKHLETISRQMMRWVKVEDIGDTEFLPEEIVDKFKFRTENNKVLEAGGRPAQGKAMLLGITKASLSTDSFISAASFQETTRVLTEAAINGKVDYLRGLKENVIMGRLVPAGTGMEYYRQVKIAGEDVVEEPVAEPLDIIPGYDEETRLQYAGGLPEDTGEESLAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MNTP_BACC0
Sequence: MTFEQLIPLIIMAFALGMDAFSVSLGMGMMALKIRQILYIGVTIGIFHIIMPFIGMVLGRFLSEQYGDIAHFAGAILLIGLGFYIVYSSILENEETRTAPIGISLFVFAFGVSIDSFSVGLSLGIYGAQTIITILLFGFVSMLLAWIGLLIGRHAKGMLGTYGEIVGGIILVGFGLYLLFPI
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DSRB_ECOSM
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNEAGHQDGIFVEKAE
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: VM3BP_BOTJA
Sequence: MIEVLLVTICLAAFPYQGSSIILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSKDYSETHYSPDGREITTYPAVEDHCYYHGRIENDADSTASISACNGLKGHFKLQRETYFIEPLKLSNSEAHAVFKYENVEKEDEAPKMCGVTQNWKSYEPIKKASQLVVTAEQQKYNPFRYVELFIVVDQGMVTKNNGDLDKIKARMYELANIVNEILRYLYMHAALVGLEIWSNGDKITVKPDVDYTLNSFAEWRKTDLLTRKKHDNAQLLTAIDFNGPTIGYAYIGSMCHPKRSVAIVEDYSPINLVVAVIMAHEMGHNLGIHHDTDFCSCGDYPCIMGPTISNEPSKFFSNCSYIQCWDFIMKENPQCILNEPLGTDIVSPPVCGNELLEVGEECDCGTPENCQNECCDAATCKLKSGSQCGHGDCCEQCKFSKSGTECRASMSECDPAEHCTGQSSECPADVFHKNGQPCLDNYGYCYNGNCPIMYHQCYALFGADVYEAEDSCFKDNQKGNYYGYCRKENGKKIPCAPEDVKCGRLYCKDNSPGQNNPCKMFYSNDDEHKGMVLPGTKCADGKVCSNGHCVDVATAY
What is the function of this protein?
Inhibits platelet aggregation.
What are the official names of this protein?
Zinc metalloproteinase-disintegrin-like bothropasin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-III subfamily. P-IIIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_RALSO
Sequence: MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNFRVDEASDA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: MNMA_STAA1
Sequence: MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNFVV
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPTA_XENTR
Sequence: MADTEEENLQSQIDEVEALTSIYGDEWCVIDEAERIFCITVSDSSNKPTWTLCLQVILPAEYPASSPPLYQLNAPWLRGEDRLTLANNLEEIYLQNLGENILYQWVEKIREFLLGKSQTSDPGPCLKSTSEETDVDDDCEIPAEELNESFKNSMLFGLNDSSGVEEIPPIIHGETITDRRSTFQAHLAPVVSPYQVKLILNKLYENKKIATATHNIYAYRIYIKERNSFIQDCEDDGETAAGKRMLHLMQILDARDVMVVVSRWYGGILLGPDRFKHINNCARNILMEHKYCSAGEESSKQTAKSKKVGKECKKKADH
What is the function of this protein?
Translational regulator that ensures constant high levels of translation upon a variety of stress conditions, such as amino acid starvation, UV-C irradiation, proteasome inhibitor treatment and glucose deprivation.  Plays a role as a negative regulator of the EIF2AK4/GCN2 kinase activity; impairs GCN1-mediated EIF2AK4/GCN2 activation, and hence EIF2AK4/GCN2-mediated eIF-2-alpha phosphorylation and subsequent down-regulation of protein synthesis.  Plays a role in differentiation of neuronal cells by stimulating neurite outgrowth.
What are the official names of this protein?
Protein IMPACT-A, Imprinted and ancient gene protein homolog A.
What is the protein family that this protein belongs to?
Belongs to the IMPACT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_PROM2
Sequence: MTLKNRYKESIRPKLLKELGLKNIHQVPKVVKVNVNRGLGEAASNSKALEASLNEMATITGQKALVTRAKKAIAGFKIREGMPIGCTVTLRGDRMYSFLERFINLALPRIRDFRGVNPKSFDGRGNYTVGVKEQLIFPEISFDKIDSIRGMDITIVTSARSDQEGKALLQELGMPFSKN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: IMDH1_ARATH
Sequence: MSTLEDGFPADKLFAQGYSYTYDDVIFLPHFIDFSTDAVSLSTRLSRRVPLSIPCVSSPMDTVSESHMAAAMASLGGIGIVHYNCGIAAQASIIRQAKSLKHPIASDAGVKFPEYEITSLDAFGPSSFVFVEQTGTMTTPKLLGYVTKSQWKRMNYEQREMKIYDYMKSCDSSDYCVPWEIDFEKLEFVLEDKQKGFVVLERDGETVNVVTKDDIQRVKGYPKSGPGTVGPDGEWMVGAAIGTRESDKERLEHLVNVGVNAVVLDSSQGNSIYQLEMIKYVKKTYPELDVIGGNVVTMYQAQNLIQAGVDGLRVGMGSGSICTTQEVCAVGRGQATAVYKVCSIAAQSGIPVIADGGISNSGHIVKALVLGASTVMMGSFLAGSTEAPGGYEYTNGKRIKKYRGMGSLEAMTKGSDQRYLGDQTKLKIAQGVVGAVADKGSVLKLIPYTMHAVKQGFQDLGASSLQSAHGLLRSNILRLEARTGAAQVEGGVHGLVSYEKKSF
What is the function of this protein?
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
What are the official names of this protein?
Inosine-5'-monophosphate dehydrogenase 1, IMP dehydrogenase 1, IMPD 1, IMPDH 1.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4HYPE_ACIBT
Sequence: MKTVKILDSHTGGEPTRLVLEGFPDLGTGDMESRRKILSEQYDHFRRATMLEPRGNDVLVGALLCKPVNPKASAGVIFFNNTGYLGMCGHGTIGLVASLAHLGKIQVGTHLIETPVGDVEATLHEDHSVSVRNVPAYRYKKAVEVDVEKYGKVTGDIAWGGNWFFLINDHGQRVASDNLDQLTEYAWTVRQALTAQGITGKDGQEIDHIELFASDTEADSKNFVLCPGKAYDRSPCGTGTSAKIACLAADGKLEPGKLWKQASIIGSQFIASYEQAGEYVIPTIRGEAYMSAEATLFMDENDPFAWGIQL
What is the function of this protein?
Catalyzes the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4-hydroxy-D-proline (c4DHyp).  Is likely involved in a degradation pathway that converts t4LHyp to alpha-ketoglutarate.  Displays no proline racemase activity.
What are the official names of this protein?
4-hydroxyproline 2-epimerase, 4Hyp 2-epimerase, 4HypE.
What is the protein family that this protein belongs to?
Belongs to the proline racemase family.
Protein: RTC1_PICST
Sequence: MSSNANSQHSTLAKFAFNIYGSLNHATPSYEGSASPSSSYSSSRSKTNEPYNYRFNKLVYNCEREVTTLSQLNYPLSLSNTFQSDQNLSHHVIIGGRNYLKLLALNEDQSRIVQDINVLDQSSIYTHNSRVPSTNKLNNINTVKAQSDTIGCGLSNGLITVYKVGSNGKCRLIHKFSDHKRCINSLDYVGIRNLYDAPTQMISGSQDGSIKLWDMRSSSPRPMLTISSGSHSDPIRSCQYSPHSQGRNKLVVLSVHDSGALCKFDLRLSNGHGPERKWNIHTGPALSLHIHPEKEYVVTGGRDQKICVFNYGDSQISNRITPDEMINTYGPVMKVRWCLYPDASTSQFGEPLDTFQQSNDFNSSSLYSYDLACSYLNDDSTVAIYNLNRKFIPKEVITTSSNKPIQNFIWANNPGSSRKIWTITKSNVFSSYDLDMHDSLLESEISKPLDELANVTVDWNNGFGDLCLANQEKYEFEITEVESQASDNDMGDIDTEYSSRYERSNSNSVIDESSLIGSSSAEKPPLFRSSTHYSMHMAKSPSPVPRRGSTSFAAHSESQPNLSNMQGLSMSRPKLTRNLSQATEDSSISIGSAPQSNIHLKSKRSFQVSYASPYLVPVSLPLSLNDENVFEILSNNYLISIPDGFTLVDVCLLNASVAASVQRFRECQIWRVLAVSLEEDYVQIDNTTFLSDPELEHNETNQDEKIDDQKDAKSISSDLGNFVGSYNSNSTSTTNYGGLGSLSAKDTTKANNSNNLMDMINRSRVNSMNHLQSISPSGSHTFIRNAIHENKSNENAIVDDDETDAAVHGTEGRIGTSHVSEDLDNENLNILNNAVLNSSPNSAMTTPHPQSNSPNYSNFFSLPKLSSTFMSPIYDEFAEKQEQPRSLKAESLLNNDVSDRTTTKSELTKAIKEEVDNSSGAPLKKAWKSSSLLEKALAHASNEGDIILCSTLSLLFYDSFKQVIPQSSCLDWLGLYIEILQRKRLFVNAIHVVNNAPDDVRSKLKNLTSGDVDLRFFCCWCQKLLVNEKSKEKLKNDVNADFGYWYCDECSQKQSNCIYCNEPCKGLTVVVSLKCGHRGHFGCLREWFIEDENNECPGGCDYSVV
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: SKI25_ARATH
Sequence: MEKKLKRRESMSTTAAESPPAKRRRTVTGNENSALIEGLPDHISEICLSLVHRPSLLSAVCTRWRRLLYSPEFPSFPSLYALFVDSTSDTGRVNPSVRFMCFNPVSSKWYPLPPPPPDPPLHRILYRHPSFISFNLPIQCVSAAGKLILIAGSNQQLSPAISHPLIFDPISSSWSSGPRIGSPRRWCATGACDGAIYIASGISSQFSSTVAKSVEKLDLTEQNRNNHRFNWEKLRDMRDLRFSREAIDAVGYRRKLLMVNVKGDAVKEGAIYDVVKDDWEPMPEEMLVGWRGPVAAMEEEILYSVDERRGTVRKYDDEKREWREVVVVEGGEEMLKGATQVTADSGKLCVVTGDGKIVVVDVAAEPAKIWNVEIPDGLEPVSVHVLPRMSQPNFC
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
F-box/kelch-repeat protein SKIP25, SKP1-interacting partner 25.
What are the subcellular locations of this protein?
Nucleus.
Protein: CCNC_DROPS
Sequence: MAGNFWQSSHSQQWILDKQDLLRERQHDLLSLNEDEYQKVFIFFANVIQVLGEQLKLRQQVIATATVYFKRFYARNSLKNIDPLLLAPTCILLASKVEEFGVISNSRLISICQSAIKTKFSYAYTQEFPYRTNHILECEFYLLENLDCCLIVYQPYRPLLQLVQDMGQEDQLLTLSWRIVNDSLRTDVCLLYPPYQIAIACLQIACVILQKDSTKQWFAELNVDLDKVQEIVRAIVNLYEMWKDWKEKDEIQMLLSKIPKPKPPPQR
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Binds to and activates cyclin-dependent kinase Cdk8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity).
What are the official names of this protein?
Cyclin-C.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RAPA_PSEPG
Sequence: MAQQYQPGQRWISDSEAELGLGTILAQDGRLLTVLYPATGDTRQYSLRNAPLTRVRFSPGDQITHFEGWKLTVREVEDIDGLMVYHGLDGQNQPRTLPETQLSNFIQFRLASDRLFAGQIDPLSWFSLRYNTLQHTSKQMQSALWGLGGCRAQPIAHQLHIAREVADRSAPRVLLADEVGLGKTIEAGLVIHRQLLSGRANRVLILVPENLQHQWLVEMRRRFNLQVALFDAERFIESDASNPFEDAQLALVALEWLVDDEKAQDALFAAGWDLMVVDEAHHLVWHEDQASTEYSLVEQLAQVIPGVLLLTATPEQLGQDSHFARLRLLDPNRFHDLAAFRAESEHYRPVAEAVQELLDEGRLSPKAHATIQGFLGAEGEALLAAVNDGDTQASARLIRELLDRHGTGRVLFRNTRAAIQGFPERQLHPYPLATPEQYRDLPAGEHAELYPEVAFQAQGEAADDERWWRFDPRVDWLIDTLKMLKRTKVLVICAHAETAMDLEDALRVRSGIPASVFHEGMSILERDRAAAYFADEEFGAQVLICSEIGSEGRNFQFAHHLVMFDLPAHPDLLEQRIGRLDRIGQKHTIQLHIPYLQDSPQERLFQWYHEGLNAFLNTCPTGNALQHQFGPRLLPLLEGGESKAWDALVADARGERERLEAELHTGRDRLLELNSGGAGEGQALVEDILEQDDQFALPIYMETLFDAFGIDSEDHSENALILKPSEKMLDASFPLGDDEGVTITYDRAQALSREDMQFLTWEHPMVQGGMDLVLSGSMGNTAVALIKNKALKPGTVLLELLFVSEVVAPRSLQLGRYLPPAALRCLLDANGNDLASRVAFETLNDQLESVPRASANKFVQAQRDVLAKRISGGEEKILPIHVERVAEAQRRLAAEADEELARLVALQAVNPSVRDSEIDALRKQREDGLAMLEKAALRLEAIRVLVAG
What is the function of this protein?
Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations.  Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA.  Does not activate transcription on linear DNA.  Probably not involved in DNA repair.
What are the official names of this protein?
RNA polymerase-associated protein RapA, ATP-dependent helicase HepA.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
Protein: THIQ_YERPE
Sequence: MLKLEKITYLYDHLPMCFDLRIQPGERVAILGPSGAGKSTLLSLIAGFLAPTGGHMLLNNQDHTASTPAQRPVSMLFQENNLFAHLTVEQNIGLGLHPGLKLSGEQRLLLQHIAQQVGLESCLDRLPAQLSGGQRQRAALARCLVRSQPILLLDEPFSALDPALRNEMLQLVDQVCINRQLTLLMVSHNLDDAARIAQRTLLIVEGRIDYDGPTQALVDGSAAKASVLGIKSAVIS
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Thiamine import ATP-binding protein ThiQ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PNP_BREBN
Sequence: MEQQYRTYDFELAGRKLTLEFGKMAKQAHGSVLVRYGDTAILSAVTVSKEPKPLDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPVRPLFAEGFRNDVQIVNTVLSVDQDCSPEIAAMIGTSAALCVSEIPFEGPIAGVIVGRIDGEFVINPTVAQAEKSDIHLTVAGTHKAINMVEAAANQVPEAIMLEAIMAGHDVIKQLVEFQNMIVSEIGKQKMEVILHEVDPEIDQAVRAYAEARLKEAVRIEEKQARYDAIDDIKAETKEHFAAKDAEAYPEQEKMISEVLGNIVKDEVRRLITDEKVRPDGRALNEIRPLSSETTILSRTHGSAMFTRGQTQALSVCTLGALGDVQILDGLGLEESKRFMHHYNFPPYSVGEARPLRPPGRREIGHGALGERAIEPIIPSEVEFPYTIRLVSEVIESNGSTSQASICASVLALMDAGVPIKAPVAGIAMGLIMSKDEKSFSILTDIQGMEDHLGDMDFKVAGTEAGVTAIQMDIKISGINREILELALEQARVGRLHILNHMMSTISEPRKELSPYAPKIMTMTINPEKIRDVIGPQGRVINKIIEETGVKIDIEQDGRVFIASINHEANLRAKQIIEDLVREVAVGQVYLGTVKRVEKYGAFIELFAGKEGLCHISQLAEERVAKTEDVVAVGDKVQVKVTEIDDQGRVNLSRKAVLKEQAAAEQAAETPTKAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURI_MYCBO
Sequence: MNSPLAPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLTIPEIRAHALAIGDDLVGRGVKALVIACNSASSACLRDARERYQVPVVEVILPAVRRAVAATRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVACPRFVDFVERGVTSGRQVLGLAQGYLEPLQRAEVDTLVLGCTHYPLLSGLIQLAMGENVTLVSSAEETAKEVVRVLTEIDLLRPHDAPPATRIFEATGDPEAFTKLAARFLGPVLGGVQPVHPSRIH
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: CH60_CITK8
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKTLSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKSTLEDLGQAKRVVINKDTTTIIDGVGEESAIQGRVTQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIAELKGQNEDQNVGIKVALRAMESPLRQIVLNCGEEPSVVANTVKSGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKGDAPDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM8B_MOUSE
Sequence: MNMPQSLGTQPLPPEPPSLGTPIEGSGAIAPTEHCWPVRPTLRNELDTFSVHFYIFFGPSVALPPERPAVFALRLLPVLDSGGVLSLELQLNASSLRQENVTVFGCLTHEVPLSLGDAAVTCSKESLAGFLLSVSATSRVARLRIPFPQTGTWFLTLRSLCGVGPRFVRCRNATAEVRLRTFLSPCVDDCGPYGQCKLLRTHNYLYAACECKAGWRGWGCTDSADALTYGFQLLSTLLLCLSNLMFLPPVVLAIRSRYVLEAAVYTFTMFFSTFYHACDQPGIVVFCIMDYDVLQFCDFLGSLMSVWVTVIAMARLQPVIKQVLYLLGAMLLSMALQLDRHGLWNLLGPSLFALGILATAWTVRSVRRRHCYPPTWRRWLFYLCPGSLIAGSAVLLYAFVETRDNYFYIHSIWHMLIAGSVGFLLPPRAKTDRRVPSGARARGCGYQLCINEQEELGLVGPGGTTVSSICVS
What is the function of this protein?
May function as a regulator of the EGFR pathway.  Probable tumor suppressor which may function in cell growth, proliferation and adhesion (By similarity).
What are the official names of this protein?
Transmembrane protein 8B, Protein NGX6.
What is the protein family that this protein belongs to?
Belongs to the TMEM8 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm. Nucleus. Mitochondrion. Endoplasmic reticulum. Note=Also detected in mitochondrion and endoplasmic reticulum.
Protein: RFCL_METTH
Sequence: MSWTEKYRPGSFDEVVGNQKVIAEIKEWIKAWKAGKPQKPLLLVGPPGTGKTTLAHIIGKEFSDTLELNASDRRSQDALMRSAGEASATRSLFNHDLKLIILDEVDGIHGNEDRGGVQAINRIIKESRHPMVLTANDPYSKRLQSIKPRCRVLNLRKVHTSSIAAALRRICRAEGIECPDDVLRELAKRSRGDLRSAINDLEAMAEGEERIGEELLKMGEKDATSNLFDAVRAVLKSRDVSKVREAMRVDDDPTLVLEFIAENVPREYEKPNEISRAYDMLSRADIFFGRAVRTRNYTYWRYASELMGPGVALAKDKTYRKFVRYTGSSSFRILGKTRKQRSLRDSVAAKMAGKMHISPKVAISMFPYMEILFENDEMAYDISEFLELRDEEIKLFRKRKIKAPKRKKTPRKAEIKVGPLYSQKKDKGADKSINDKATDKSAKTPIKSSKKDDRPRDESSSSSDDKKPKEKQTSLFQFS
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.  The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA.  In conjunction with PCNA stimulates DNA synthesis by PolB, relieving inhibition by replication protein A (RPA).
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit, MthRFC large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: RR7_EMIHU
Sequence: MSRRSKSKRVLAQPDPIYNSRLVNLLVIRVLKSGKKSVAQKIVYTALEIIAEKTNENPILLLEKAVTNVTPQVEVKARRVGGSTYQVPIEIRAYRGTNISLKWLIEFARERSGRGMASKLANEIIDAAKNAGGSIRRKEQTHKMAEANKAFAHFRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL3_METTP
Sequence: MATIHRPRRGSLAFSPRKRAKSEVPRIRSWVADERAGMAGFAGYKAGMTHVIMIDDRPRSLTEGMEISVPVTVVEVPPMSVAALRVYEPYNGGIRPAGELWAENLSQDLERAITIPKARRGASLEDIESRVDELCEIRVLAHTNPRLLTGVPKKVPDIMEIPVTGRSVEEQLKAAEGLLGSQVAVSNIFNVGEWIDVSAVTKGKGTQGPVKRWGIMLQKRKHSRTGKLRHVGNLGPWHPARISWRVPQLGQTGYHQRTEFNKRIMAIGTNGTDITPDGGFVGYGVVRNEYMLIKGSVPGPVKRLVRMRRAIRPGAAFAPKAPQILYVSKESKQGV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CH60_ACTP2
Sequence: MAAKDVKFGNDARVKMLKGVNVLADAVKVTLGPKGRNVVLDKAYGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVNEGLKAVAAGMNPMDLKRGIDKAVVAVVEELKAISKPCETSKEIEQVGTISANSDETVGKLIAQAMEKVGKEGVITVEDGTGLDDALDVVEGMQFDRGYLSPYFINKPEAGTVELENPYIILVDKKISNIREILPVLEAVAKAGKPLLIVAEDIEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIAILTAGTVISEEIGMELEKATLEELGQAKRVVITKDNTTIIDGIGDEAQIKARVAQIRQQIEDSTSDYDKEKLQERVAKLACGVAVIKVGAATEVAMKEKKDRVDDALHATRAAVEEGIVPGGGVALVRAASKVAATLTGDNEEQNVGIKLALRAMEAPLRQIVTNAGEEASVVARNVKDGNGNYGYNAGTEQYGDMLEMGILDPTKVTRSALQFAASIAGLMITTECMITDLPKEEKLDPAAAMGGMGGMGGMI
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIM23_YEAST
Sequence: MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM23, Membrane import machinery protein MIM23, Mitochondrial protein import protein 3, Mitochondrial protein import protein MAS6.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Note=Around 20 amino acids of the N- terminus are believed to span the mitochondrial outer membrane. This association is dynamic and depends on the translocation activity of the TIM23 complex. However, this topology seems not to be critical for formation of a TOM-TIM supercomplex and preprotein import.