PharMolix/UniProtQA huggingface dataset:
Protein: NADD_SACD2
Sequence: MGKAHATPQLLFGGTFNPVHNGHLVSAMAAREALGVDSVTLLPCYVPPHKTAPTIAAEHRLAMLQHVVQENNHLCIDTCELDAGESIFTVDTLAAKRELWGASASIIWLIGWDSLHNLSRWHRWQSLLTFANLAVVERPFAQSDDINSLPPAVRNWLQQHRVSAKQLTQQANGGVALLHTPRIELSSSDVRQRLGAQKSIQYMVPACVETYIRAHKLYTH
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: EXGD_ASPNC
Sequence: MPGHSRSRDRLSPSSELDDADPVYSPSVYQREHYYNNDSLFDSADDDYTRTPRNVYSYETHDEYHDDDDDDDDVHEHDHDHEYDDKFEEPWVPLRAQVEGDQWREGFETAIPKEEDVTQAKEYQYQMSGALGDDGPPPLPSDALGRGKGKKRLDRETRRQRRKERLAAFFKHKNGSASAGLVSGDALAKLLGSQDGDEDCLSHLGTERADSMSQKNLEGGRQRKLPVLSEEPMMLRPFPAVAPTGQTQGRVVSGAQLEEGGPGMEMRHRGGGGPPAEGLLQKEGDWDGSTKGSSTSARPSFWKRYHKTFIFFAILIVLAAIAIPVGIIEARRLHGTSGGDNSSNSNLKGISRDSIPAYARGTYLDPFTWYDTTDFNVTFTNATVGGLSIMGLNSTWNDSAQANENVPPLNEKFPYGSQPIRGVNLGGWLSIEPFIVPSLFDTYTSSEGIIDEWTLSEKLGDSAASVIEKHYATFITEQDFADIRDAGLDHVRIQFSYWAIKTYDGDPYVPKIAWRYLLRAIEYCRKYGLRVNLDPHGIPGSQNGWNHSGRQGTIGWLNGTDGELNRQRSLEMHDQLSQFFAQDRYKNVVTIYGLVNEPLMLSLPVEKVLNWTTEATNLVQKNGIKAWVTVHDGFLNLDKWDKMLKTRPSNMMLDTHQYTVFNTGEIVLNHTRRVELICESWYSMIQQINITSTGWGPTICGEWSQADTDCAQYVNNVGRGTRWEGTFSLTDSTQYCPTASEGTCSCTQANAVPGVYSEGYKTFLQTYAEAQMSAFESAMGWFYWTWATESAAQWSYRTAWKNGYMPKKAYSPSFKCGDTIPSFGNLPEYY
What is the function of this protein?
Glucosidase involved in the degradation of cellulosic biomass.  Active on lichenan (By similarity).
What are the official names of this protein?
Probable glucan 1,3-beta-glucosidase D, Exo-1,3-beta-glucanase D.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: PLS21_PHYTB
Sequence: FLSLIPHIATGIAALAKHL
What is the function of this protein?
Has antimicrobial activity against Gram-negative bacterium E. coli ATCC 25922 (MIC=50 uM), Gram-positive bacterium S. epidermidis ATCC 12228 (MIC=12. 5 uM) and against fungus C. albicans ATCC 24433 (MIC=100 uM) (PubMed:29980138).  Has an anti-inflammatory effect, since it inhibits the production of the pro-inflammatory cytokines TNF-alpha, and induces the production of the anti-inflammatory cytokine IL-10 (PubMed:30734396).  Is cytotoxic to cancer line cells (PubMed:30734396).  Shows moderate hemolysis on mouse erythrocytes (LC(50)=41 uM) (PubMed:30734396).
What are the official names of this protein?
Phylloseptin-2.1TR, PLS-2.1TR, Phylloseptin-2.2TR.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Phylloseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: OSTF1_MOUSE
Sequence: MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTSWWKGTCKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHKDIVEVLFTQPNVELNQQNKLGDTALHAAAWKGYADIVQLLLAKGARTDLRNNEKKLALDMATNAACASLLKKKQQGTDGARTLSNAEDYLDDEDSD
What is the function of this protein?
Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.
What are the official names of this protein?
Osteoclast-stimulating factor 1, SH3 domain protein 3.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUMBL_MOUSE
Sequence: MSRSAAASGGPRRPDQHLSPAPCGASGPPETFRTESDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAGDKKKAEAAAAPAVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGTGDSDGINALCTQISSSFASAGAPASGPPPATTGTSAWGEPSVPAAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQATSVPPMPTMAPTLQPFSAPVGPFDTAAAQVAVFLPPTHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAAPSAPGGQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKPAVEKPSNPFSGDLQKTFEIEL
What is the function of this protein?
Plays a role in the process of neurogenesis.  Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate.  Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis.  Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity.  Negative regulator of NF-kappa-B signaling pathway.  The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons.
What are the official names of this protein?
Numb-like protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Symmetrically distributed throughout the cytoplasm in non dividing neuroblasts of the CNS.
Protein: LSRE_SALPB
Sequence: MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDVHLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLGQQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQLLAVNPGYGSKMRSSDLHERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAMFKVAGDTTFLPSTA
What are the official names of this protein?
Putative epimerase LsrE.
What is the protein family that this protein belongs to?
Belongs to the ribulose-phosphate 3-epimerase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: UVRB_PAEAT
Sequence: MSLAQEINRVVAPFEVISEFKPAGDQPTAIAELTERINNGEKDVVLLGATGTGKSATTAWLIEQVQRPTLVMVQNKTLAAQLANEFRELLPNNAVEYFVSYYDYYQPEAYVAQTDTFIEKDSSINEEVERLRHSATNALLTRRDVIVVATVSCIYGLGTPEEYIAGMVTLRKGAEMNRDHLLRKFVSMQYARNDMDFHRGTFRVRGDTVEIIPMYEELAIRIEFFGDEIENIQTLHPLTGEVLRDEEEMYVFPASHYVAGPERMARAIKRIEDELADRLKVLEGQNKLVEAQRLRMRTTYDLEMMQQMGFCNGIENYSVHIDGRNPGTAPHCLIDYFPDDFLLVVDESHVTIPQIGAMYEGDMSRKRNLVDFGFRLPSAMDNRPLKWDEFLERIGQTVYLSATPGKYELGKADGYVQQIIRPTGLIDPEVVVKPTKGQIDDLLGEIRTRTEKNERVLVTTLTKRMAEDLTDYLVGHGVKVEYLHSDVDTLRRVELLRELRMGVFDVLVGINLLREGLDLPEVSLVSILDADKEGFLRSSTSLIQTIGRAARNVSGQVHMYADRITDSMAHAIEETNRRRAIQVQYNTDHGIDPQPLRKKIADITDQLAKEDADTQELLNNNRLAKGGKRGKSAAKGAATVRQDGLAAAPAEDLVGLIEQLTEQMHGAAAELQFEVAARIRDEVKELKRELRQMQSAGHA
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_AGRFC
Sequence: MTAITDIIAREILDSRGNPTVEVDVYLEDGSMGRAAVPSGASTGAHEAVELRDGGKRYLGKGVEKAVEAVNTEIFDAIGGFDAENQIQIDQMMIALDGTPNKSRLGANAILGVSLAIAKAAAEASGLPLYRYVGGPNAHLLPVPMMNIINGGAHADNPIDFQEFMILPVGAENIREAVRMGSEVFHTLKKELSAQGHNTNVGDEGGFAPGLESAPAALDFIMKSIEKAGYRPGEDMYVGLDCASTEFFKDGKYVLEGEGRTLEPGAMAEYLAELVNKYPIISVEDGMAEDDWEGWKTLTDLVGNKCQLVGDDLFVTNSARLRDGIKMGVANSILVKVNQIGSLSETLDAVETAHKAGYTAVMSHRSGETEDSTIADLAVATNCGQIKTGSLARSDRLAKYNQLIRIEEMLGPQAAYAGRSILRG
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PLSY_SALDC
Sequence: MSAIAPGMILFAYLCGSISSAILVCRIAGLPDPRESGSGNPGATNVLRIGGKGAAVAVLIFDILKGMLPVWGAYALGVTPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKPQFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKLKKKRQKD
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-ACP to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme can also utilize acyl-CoA as fatty acyl donor, but not acyl-PO(4).
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COX3_SOYBN
Sequence: MIESQRHSYHLVDPSPWPISGSLGALATTVGGVMYMHSFQGGATLLSLGLIFILYTMFVWWRDVLRESTLEGHHTKVVQLGPRYGSIPFIVSEVMFLFAFFWASSHSSLAPTVEIGGIWPPLGIWVLDPWEIPFLNTPILLSSGAAVTWAHHAILAGKEKRAVYALVATVSLALVFTGFQGMEYYQAPFTISDSIYGSTFFLATGFHGFHVIIGTLFLIICGIRQYLGHLTKEHHVGFEAAAWYWHFVDVVWLFLFVSIYWWGGI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: APT_KLULA
Sequence: MSITEYATELKGALRQYPNFPQEGILFEDFLPIFRDPQLFKKLIESFKLHLQEKFTGKKIDYVIGLEARGFLFGPALALALDAGFVPVRKQGKLAGEVVHAVYAKEYGEDVFEIQADSIPEHSNVVIVDDIIATGGSAKAAGDLALQLNANILEFCFVMELDFLKGTQKLQAPSFTLLSGQEEALSK
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KDPC_DECAR
Sequence: MKTLLRPAVSLFVLLTAVTGVVYPLAVTGIAKVTFPEAADGSLIVKDGKTVGSSLIGQNFSDPKYFWGRPSATSPMPYNASSSSGSNQGPLNPALVDAVKVRIEALKAADPDNKLPIPADLVNASASGLDPHISPEAAAYQVTRVAGQRHLLPADVKALVSQHTEGRQWGVFGEPRVNVLQLNIALDSVSK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GLGC_RHOPT
Sequence: MSQGVTAPFARHAMAYVLAGGRGSRLMELTDWRAKPAVYFGGKSRIIDFALSNALNSGIRRIAVATQYKAHSLIRHLQRGWNFFRPERNESFDILPASQRVSEEMWYRGTADAVFQNIDIIESYDPKFIVLLAGDHVYKMDYEKMLQQHVEQGADVTVGCLEVPRAEATAFGVMHTDTTDRIISFLEKPADPPAMPGKADKSLVSMGIYVFETKFLLDELRRDAADPNSSHDFGKDIIPYIVKHGKAVAHHFDKSCRRSSSEAVSYWRDVGTVDAYWAANIDLTDIVPELDLYDREWPIWTYGEITPPAKFVHDKEGRRGEAVSSLVSGGCIISGASLRHSLLFTGVRVHSFSHVENTVVLPYADIGRSCRLKNVVIDAEVKLPAGLVVGEDPELDAKRFRRTENGICLITRAMIEKLDA
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: PRIB_NITEU
Sequence: MIPNPDPESSINRNQVIISGTITDLASPRYTPAGLMIAEFKLSHCSNQQEAGIQRRIEFEFEAIAIAETAEKIIRIGSGSNVEITGFIAKKNRLSNQLVLHVRDTRII
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: LYSC_LOPLE
Sequence: KVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKYESNFNTHATNRNTDGSTDYGILQINSRWWCNDGKTPGSRNLCHIPCSALLSSDITASVNCAKKIVSDGNGMNAWVAWRNRCKGTDVSVWTRGCRL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MINE_ALKEH
Sequence: MGFLSYFRSQKKRSASVAKERLQIIVARERSQTATGPDYLPMLKEELLDVIRKYVQVDRDAVNFQLDREGDCEVLELNITLPDQQDQAAAHDRG
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: GTFB_STRGN
Sequence: MIQLFDYYNQETQDLHDSLLAAGYACPTIVIEANGFLPDDMISPYTYFLGDEEGVDHPLFFNQVPVPPFWEITGDHQVARVSDMGEERARIHYASQARGRLVKQVDWLDKKGQLRLSERYNKQGRCFAKTAYKSGQEAFNTTYYSTDGQERIVENHVTGDIILTLDQEPLRIFKSRVDFIRFFLERLDLDLDHILFNSLAYSFLVSHSLTGRAGQDILFWQEPLYDELPGNMQLILDNSQLRTQTIVIPDLATYEKAMSLAAADQQQKFLHLGYHYDFKRDNYLRKDALILTHSDQIEGLDTLVQSLPQLVFRIAALTEMSPKLLSMLSYKNVVLYQNASLKQIEQLYLESDIYLDINHGGQVLQAVRKAFENNLLILGFEQTLHDRHYIAQQHIFDSSQPAQLASILEEALCGVEQMRSALQAQGRHANDVPVSLYQETLQSLLGGQHG
What is the function of this protein?
Required for polymorphic O-glycosylation of GspB, a serine-rich repeat cell wall protein encoded upstream in the same operon.  A substrate-binding protein that is part of the accessory SecA2/SecY2 system specifically required to export GspB.  The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to GspB, attaching the first sugar residue.  Upon coexpression in E. coli with GtfA glycosylates GspB constructs (PubMed:15489421).  Binds the GspB protein substrate; alone this subunit only recognizes partially glycosylated GspB, but is constrained by GtfA to also recognize unglycosylated protein.  The enzyme probably modifies its tertiary conformation by opening and closing its intersubunit interfaces to accomodate the increasingly glycosylated substrate (Probable).
What are the official names of this protein?
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase stabilizing protein GtfB, Glycosyltransferase stabilizing protein GtfB, orf4.
What is the protein family that this protein belongs to?
Belongs to the GtfB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS21_BACVZ
Sequence: MSKTVVRKNESLEDALRRFKRSVSKTGTLQEARKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: VIAA_YERPA
Sequence: MLSLATLDMLLSISEGELIEEMVVGLLAAPQLAIFFEKFPRIKRALMKDIPGWKQNLQQRIREASVPPGLANEFSLYQQSLLEDSPQFYAHLPDIVAQLQDLHSPFATQAKTLVQTADLAKNPPGGDSLQTLFLQRWRVSLILQTITIHHQLLEQEREQLLAELQRRLALSGALEPILTTNDNAAGRLWDMSQGHLQRGDYQLLLQYGDFLQQQPELIRLAEQLGRSRSAKAQPAPDARYEPYTVMVRQPDSVPEEVSGIHQSNDILRLLPTELVMLGMSELEFEFYRRLLERRLLTYRLQGDNWQEKTQQRPVSLKQNDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALLRIALADNRRCYIMLFATEIIHYELSADNGIEQAIRFLNQHFRGGTDLAACLANTLNKMEDREWYDADAVIISDFIAQRLPEELVRKIKIQQQAHQHRFHAVAMSAYGKPGIMRIFDHIWRFDTSLKSRLIRRWKR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: NIKE_RHORT
Sequence: MSPLLTARAASKSYRTVSLVGRSPAKTVLSEATVTLSEGETVALLGRSGSGKSTLARLLLGLEKPDHGTIAFRGRPLGGFSRAEWRAFRGAVQMVFQDSLGAVNPRHRVGRIIGEPLRHLTTLDDAGRAARRDALLRQVGLTPEDADKLPQQMSGGQLQRVCIARALAPGPRLLVLDEAVSNLDLMLQIQMIDLLKDLQRQTGMAYLFVTHDLRLVERFCQRVIVLDEGKIVEEAPVTGAQRFEHPASRALQRAILPARPAAASVGDDEGGRRSATR
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIMO_ECO45
Sequence: MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWRKICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUCC_GLAP5
Sequence: MNLHEYQGKQIFAKYKLPVSQGIACKTADEAVEAIKQLKGDAWAIKCQVHAGGRGKAGGVKLVRNEAEVREFADKWLGKRLVTFQTDANGQPVNTLYVEETAGIARELYLGAVIDRSSQKVVFMASSAGGMNIEEVAAKTPELLHKVAIDPLVGGMAYQGRELAFKLGLTGDQIKQFSFIFTQLAKLFVEKDLSLLEINPLVVTTEGNLLCLDAKMVVDGNALYRQPELAAMHDPSQDDPREALAESHQLNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGFPANFLDVGGGATKERVAEAFKIILSDKAVKAVLVNIFGGIVRCDLIADGIIAAVNEVGVNVPVVVRLEGNNAELGREILAKSGLNIIAAATLTDAAVEAVKAAGGK
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: TRPF_STAA3
Sequence: MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: SYI_PARUW
Sequence: MFEEVLQESFDEREKKVLKFWQEGQLFERSVENRKGQPLFTFYDGPPFATGLPHYGHILAGTIKDVVLRYKTMKGFCAPRRFGWDCHGLPVENEIEKTFGLSGAKSIEEFGIAKFNEECRNIVLRYTEEWKFTVNRMGRWVDFNQTYRTMDLPFMESVWWVFKQLYAKGLVYEGLKVMPFSAKLGTPLSNFEASENYKEVDDPSLTVAFQSRDNSNTYFLAWTTTPWTLVSNLALMVSPMIEYAEVQDHVSKRNYILATERLKGYYKDSGEYTIVRKFPGSELEGQHYIPLFDYFNDRAHSGAFKIILEDSISVEEGTGIVQTAPAFGEIDFYACQKAGIDPVCPVDNNGQFTDEIPEYKGIFVKEADKDIIKRLKQQAKVIHQGTCHHRYPFCPRSDTPLIYKTVRTWFVAVEKIKDRLLAANSQIHWTPEHIQYGRFGKWLEGARDWAISRNRYWGTPIPLWRAQDGEIHVVGSIEELKQLTGNPLTDLHRHFIDEMSFEKNGKTFKRIPEVFDCWFESGSMPYAQNHYPFENRELFEQNFPADFIAEGLDQTRGWFYTLTVLSAALFDQPAMKNVIVNGLILAENGAKMSKRLKNYPDPAEVIQQYGADAIRLYMLHSPAVKADDLSFSKSGVELVLRQILLPLWNAYTFFLTYARIYNWKPGKLVQKPELAIDQWIISLLNKLVHEVEQGMDDYDLSRSVEPFVNFVDQLTNWYIRRSRRRFWDDKESPNRTQAFETLYYVLIELTKISAPYVPFISEAIYQNLRSCDMPESVHLCDFPHYQQLSRHEKLEAEMEAVQVTVSLGHALRKEHKLKVRQPLATAQLASADPKVLDFLKEQQHLISEELNVKEITFSSNEKDFVSLKAKPNFRVLGKKVGKLMKLAQLTIEQFGQKELTELLNHRSVEIILEGHPVLLTSEDVQVERIVREGIIAANQGTITIALNTNLNKELLLEGLAREIVNKVNTMRREANFAVTDRIQLYMQTTTRVIECFDQYKNYICQEVLATDVQFGPYEGTDWDLNGEPTKIIIKKSEY
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NAS25_CAEEL
Sequence: MQIYLGITICLVAFLTVIDCAIPYYRTHSNFGSLGRRKVRQVQRDLTYRWPNNTVPYYVGNVTSTIKKSVRLAIEELQAWTCIRFQNVNEKYSDGDSVRIVDLGSCSSPIGRQQIGTQDVSLTKNCWGMGTAIHELMHAIGIEHTQSRSDRNRYLDILAQNIDNRDLPNFELLSPRLWANLVPYDYGSVMHYSADSFSNKDDEQTMLPKDRSFIETMGSMIPNFYDFDQINQYYQCYDSCRNAGQLANCANGGIPNPNNCQVCNCPMGYGGDLCDQRPEGCGSTLVATDRWQKQKLSVRFSRNDDQYFTFCNSWIVGPSDRTLQVIYEITSDSIRRQICSFGCYEGGIEVKHLQDPRITNDRDCCLNTPLNLTTTVNPLPVILYTSGATVTYDFSYRYV
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Zinc metalloproteinase nas-25, Nematode astacin 25.
What are the subcellular locations of this protein?
Secreted.