PharMolix/UniProtQA huggingface dataset:
Protein: BHA09_HUMAN
Sequence: MLRGAPGLGLTARKGAEDSAEDLGGPCPEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCASCPPHAPLARPSAVAEGPGLAQASGGSWRRCPGASSAGPPPWPRGYLRSAPGMGHPRS
What is the function of this protein?
Transcription factor, which play a role in limb development.  Is an essential player in the regulatory network governing transcription of genes implicated in limb morphogenesis.
What are the official names of this protein?
Class A basic helix-loop-helix protein 9, bHLHa9, Class F basic helix-loop-helix factor 42, bHLHf42.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LEUC_SYNY3
Sequence: MSARTLFDKVWDLHTISVLPSGQTQLFIGLHLIHEVTSPQAFAMLKERGLRVMYPERTVATVDHIVPTENQQRPFQDSLAEEMMQALEVNTKAHNIRFHPIGSGNQGIVHVIAPEQGLTQPGMTIACGDSHTSTHGAFGAIAFGIGTSQVRDVLAAQSLSLNKLKVRKIEVNGDLAPGVYAKDVILHIIRKLGVKGGVGYAYEYAGSTFVAMNMEERMTVCNMSIEGGARCGYINPDEVTFAYLKGREFAPQGEDWDKAVQWWRSIASEPDAVYDDVVSFRAEDIEPTVTWGITPGQGIGISEPVPTLDSLNPDDQAIASEAYKYMQFQPGQPLKGTKVDVCFIGSCTNGRLSDLEEAAKVAKGHQVAAGVKAFVVPGSEQVKQQAEAAGLDQIFQAAGFEWREAGCSMCLAMNPDKLQGDQLSASSSNRNFKGRQGSASGRTLLMSPAMVAAAAITGQVADVREVLG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: DDL_STAAR
Sequence: MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYITNDGDWRKQNNITTEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSIGISKCSNEVELKEGIKEAFQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYPELITKLIELAKERHQDKQKNKYKID
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y162_HELPJ
Sequence: MGRAFEYRRAAKEKRWDKMSKVFPKLAKAITLAAKEGGSEPDTNAKLRTAILNAKAQNMPKDNIDAAIKRASSKEGNLSEITYEGKANFGVLIIMECMTDNPTRTIANLKSYFNKTQGASIVPNGSLEFMFNRKSVFECLKSEVENLKLSLEDLEFALIDYGLEELEEVGDKIIIRGDYNSFKLLNEGFESLRLPIIKAGLQRIATTPIELNDEQMELTEKLLDRIEDDDDVVALYTNIE
What are the official names of this protein?
Probable transcriptional regulatory protein jhp_0149.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQJA_BACSU
Sequence: MFKIGYRTIKTALGTALAIYISQLLHLQNFASAGIITILCIQITQKRSLQASWARFSACCLAIAFSYLFFELIGYHPFVIGALLLIFIPITVLLKINEGIVTSSVIILHLYMSGGITPTFIWNEVQLITVGIGVALLMNLYMPSLDRKLIAYRKKIEDNFAVIFAEIERYLLTGEQDWSGKEIPETHQLITEAKNLAYRDVQNHILRYENLHYHYFKMREKQFEIIERLLPKVTSISITVDQGKMIAEFIHDLREAIHPGNTAYKFLKRLADMRKEFEEMPLPATREEFEARAALFHLLGEMEQYLVIKSYFKGIKAQKSLG
What are the official names of this protein?
Uncharacterized protein YqjA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPE_VIBCH
Sequence: MDAAPMIHGTTVWPSPAKLNLFLYITGRRANGYHDLQTLFQFLDHGDELTITANNSGNITLSPALADVALEDNLIYKAAMALKNAAQSPLGADIQLHKVLPMGGGIGGGSSNAATTLVALNYLWQTGLSDDQLAEIGLALGADVPVFTRGFAAFAEGVGEELSAVEPEEKWYLVVRPAVSIATKDIFTHPQLMRNTPKRDLASLLTTPYENDCEKIVRSLYPEVDKQLSWLLQYAPSRLTGTGSCVFAEFSSRKDAQAVFAQLSDNVLAFVAQGRNVSPLRKTLADYQSAKIRPY
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SPXH_STAAU
Sequence: MENKSREDINLSPVSKIEIYSFFDPFSSDCFKLSAILSKLRIEYNQYIRIRHILNPSLKVLTKCQAQSTSNFDNIALAYKAAELQGRVRAERFIHLMQNEIIPKRDIITESMICDCIQNAGIDLEVFKDDLQKSKLTESLKIDLHIAREMEIEQAPSLVFFSEDVHEEGLKVEGLYPYHIYTYIINELMGKPIEKNLPPKLETYIQQQQLVTMEELLTIYEWPEKLLNKELKKLAIQQKIEKLKYPDGDFWKSKMPKIKSK
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions.  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP.
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_SERP5
Sequence: MSDNSQKKVIVGMSGGVDSSVTAYLLQQQGYQVAGLFMKNWEEDDDEEYCSAATDLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLEEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADFIATGHYVRRQDVDSKSRLLRGVDGNKDQSYFLYTLSHEQVAQSLFPVGELEKPEVRRIAEQLELVTAKKKDSTGICFIGERKFRDFLGRYLPAQPGPIVSVDGQTVGEHQGLMYHTLGQRKGLGIGGMKDSSEDPWYVVDKDVANNVLVVAQGHEHPRLMSVGLIAQQLHWVDRLPLSGPFRCTVKTRYRQQDIPCTVTPLDEQRIEVRFDEPVAAVTPGQSAVFYQDEICLGGGIIEQRLQE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis.  Sulfur is provided by IscS, via a sulfur-relay system.  Binds ATP and its substrate tRNAs.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL33_MESM1
Sequence: MARDGITLRCEECKMENYITKKNKKLHTEKLETKKFCPKCNSHVTHKEKK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: HIS4_ARTS2
Sequence: MTTETPLPVLELLPAVDVVNGQAVRLVQGEAGSETSYGTPLEAALNWQEQGAEWVHLVDLDAAFGRGSNAELLREVVGRLDIKVELSGGLRDDESLEKALDLGVARVNLGTAALENPEWTARAIDRFGDKIAVGLDVRGTTLAGRGWTKEGGDLWDVLARLEEAGCARYVVTDVTKDGTLQGPNVELLRKMVERTGKPVVASGGISSLEDLKVLRSLVPLGVEGAIVGKALYAGAFTLPEALDVAGRR
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX16_PARBD
Sequence: MVFQAKRFRPSNSFGSTLSERLGAKYRANLSKHPFLLFGLPFISVIIAGSFVLTPATAMRYERFDRKVQQVSQEEAMGLGLKGPEGDDGVQIKRNPRRRILGSEKEEYYKLMAKDLDNWEQKRVKRFKGEPDGRL
What is the function of this protein?
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase.  May participate in merging the COX1 and COX2 assembly lines.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX16, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: ISPDF_DESVH
Sequence: MRTWVLLLAAGSGTRLATAGLPDAKQFLPLHGAPLYWASARTMAHVAGIEGIVFVFPPHRVEEERARISALDDGSVLGLDWHVVGGGAARQDSVACGLAALPRSCEAVLVHDAARPFASPALVARVLSALHDGHAGVVPGIPLTDTVKETTDGFVANTPDRSRLVAVQTPQGFTLKALSTAHETARTAGWNVTDDAALLERCGIPVRIVAGEVVNAKITTPEDLAMLDANEPQVTVPCVGWGYDVHRYGEGRPMKLGGVLIPEGPEVVAHSDGDVLLHALADALLGCIGAGDIGLHFPDSDAAFDNANSAMLLDRVLHMTHEARLRLTHVDLTIVAQVPKLSPWRDKIRANVARLLDLPVTSVNFKATTEEGLGFTGEKRGIKAIAAVTGLRPMP
What is the function of this protein?
Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
What are the official names of this protein?
Bifunctional enzyme IspD/IspF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the IspF family.
Protein: VG45_ICHVA
Sequence: MTFQFQNEWNPILSDISDSIVDRTAAQWTPATYWGLLEADARAIRPVQQYVCNGPCCSTLWAGPVPGYVITQFVPPVTYPNPYRVVAAPGCAPGSEWCEPPTVSAPPPPSQFSDEPTSPELAPAVPKIDIHEAPVATVSSPTSPRPITTESSRVSPTKEKWGRKRVHKKTHAEATWIPQILKRGMSLSSLLPAAARGQRSAVRRRVTFTNSKDVLYYDKYSAPVMIQGNTVYVEKTFSDK
What are the official names of this protein?
Uncharacterized protein ORF45.
Protein: CA1B_CONAL
Sequence: MFTVFLLVVLATTVVSFTSDRASDGRKDAASGLIALTMKGCCSYPPCFATNPDCGRRR
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin blocks mammalian nAChR alpha-3-beta-4/CHRNA3-CHRNB4 subunits.  Also exhibits inhibition of D. melanogaster alpha-7 nAChRs (PubMed:25466886).
What are the official names of this protein?
Alpha-conotoxin AuIB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPE_BURCM
Sequence: MATIKVDVVSAEEQIFSGEAKFVALPGETGELGILPGHTPLITRIRPGAVRIEVEGGNDEFVFVAGGILEVQPGAVTVLADTAIRGKDLDAAKAEEARKRAEETLQNAKSDLDLAKAQSELATAMAQLEAIQRLAKIRSRH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL28_OCEIH
Sequence: MARKCVVTGRQTRSGNQRSHAMNSNKRNWKANVQKVRIMVDGKPKKVYVSARALKSGKVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: BZP63_ARATH
Sequence: MEKVFSDEEISGNHHWSVNGMTSLNRSASEWAFNRFIQESSAAADDGESTTACGVSVSSPPNVPVDSEEYRAFLKSKLNLACAAVAMKRGTFIKPQDTSGRSDNGGANESEQASLASSKATPMMSSAITSGSELSGDEEEADGETNMNPTNVKRVKRMLSNRESARRSRRRKQAHLSELETQVSQLRVENSKLMKGLTDVTQTFNDASVENRVLKANIETLRAKVKMAEETVKRLTGFNPMFHNMPQIVSTVSLPSETSNSPDTTSSQVTTPEIISSGNKGKALIGCKMNRTASMRRVESLEHLQKRIRSVGDQ
What is the function of this protein?
Transcription factor involved in controlling responses to starvation (PubMed:26263501).  BZIP2-BZIP63-KIN10 complex binds to the ETFQO promoter to up-regulate its transcription (PubMed:29348240).
What are the official names of this protein?
Basic leucine zipper 63, AtbZIP63, bZIP protein 63, Basic leucine zipper OPAQUE 2 homolog 3, Basic leucine zipper O2 homolog 3.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LGI1_PANTR
Sequence: MESERSKRMGNACIPLKRIAYFLCLLSALLLTEGKKPAKPKCPAVCTCTKDNALCENARSIPRTVPPDVISLSFVRSGFTEISEGSFLFTPSLQLLLFTSNSFDVISDDAFIGLPHLEYLFIENNNIKSISRHTFRGLKSLIHLSLANNNLQTLPKDIFKGLDSLTNVDLRGNSFNCDCKLKWLVEWLGHTNATVEDIYCEGPPEYKKRKINSLSSKDFDCIITEFAKSQDLPYQSLSIDTFSYLNDEYVVIAQPFTGKCIFLEWDHVEKTFRNYDNITGTSTVVCKPIVIETQLYVIVAQLFGGSHIYKRDSFANKFIKIQDIEILKIRKPNDIETFKIENNWYFVVADSSKAGFTTIYKWNGNGFYSHQSLHAWYRDTDVEYLEIVRTPQTLRTPHLILSSSSQRPVIYQWNKATQSFTNQTDIPNMEDVYAVKHFSVKGDVYICLTRFIGDSKVMKWGGSSFQDIQRMPSRGSMVFQPLQINNYQYAILGSDYSFTQVYNWDAEKAKFVKFQELNVQAPRSFTHVSINKRNFLFASSFKGNTQIYKHVIVDLSA
What is the function of this protein?
Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1.  It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit.  Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors.  Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity).
What are the official names of this protein?
Leucine-rich glioma-inactivated protein 1.
What are the subcellular locations of this protein?
Secreted. Synapse.
Protein: TPIS_SYNPW
Sequence: MRKPVIAGNWKMHMTCAQTRDWMGTFLPLISETPDDRHLVIAPPFTAISTLADVGAGSRVEISSQNVHWEGHGAYTGEISPAMLQEHGVRYAIVGHSEPRKYFSESDEQINHRARSAQAHDLIPIVCVGESDEQRSRGEAERVIRRQVEQGLEGLDPQRLVVAYEPIWAIGTGKTCESAEANRICGLIRSWVGSPDLIIQYGGSVKPANIDELMGMSDIDGVLVGGASLDPEGFARIANYKKG
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPP_NOCFA
Sequence: MTSTLVLASASPARRQVLRAAGIDPVVRVSDVDEDAVAAALPPDTAPATVVVELARAKAAAVAADIPEYAADCVVVGCDSMLLLDGELQGKPHTPEVARARWAQMAGRSAELVTGHCVLRLRGGAVVAEATDCSATTVHFAKPEPEELDAYLASGEPLQVAGAFTLDGLGGWFVDRIEGDPSSVIGIGLPLLRRLLGDVGVGVAQLWRHPAR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBS_CLOB8
Sequence: MKKLYKGFIMALSMFTILPTPYVEWDDDGVKNMMKFYPLIGLIIGVLWSIIYYLASILNASIILKSSIITIVPFIITGMLHLDGFMDVCDAILSRRSKEEKLRILKDSATGAFAVIPLVILFFLQFGGVYSILEKNSSLYTLILIPIISRSVVAYYLLSRATIKESTLGTYFKKGTNVYDKLIMIITLIITLIISVILLNIYGIILVLLMSLGIKLSVEKCRKEFGGISGDVAGFALVIGEVVGILILGIIP
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCMM_SYNP2
Sequence: MVVRSTAAPPTPWSKDLAEPKIHESAYVHSFSNLIGDVTVCEHVLISPGTSIRADEGAPFHIGAATNIQDGVVIHGLEQGRVVGADGHDYSVWIGDRSCITHMALVHGPAYIGNDCFVGFRSTVFNARIGDGCVIMMHALVQDVDIPPGKYVPSGAVITNQQQVERLSNVTEADRAFAKQVVEINEALREVSPGATNNGSRIAANQQPTPSSSTNTSGTSEHQSVGNMSLNGDLYNQVRGLAAQGCTFTAEYANKRRFKTKSWLSAGFVEGHSADQIIGNLNRVLADHAGEYVQLIAVAPNSKSRAAEIVVQRPGDSAPVQTSTTASYSNNGNRSNGTSAGSQAAAVGGDLTSQIHALASQGCSFTAEHANTRRFKTQSWLSAGFVEGHSAEQIITNVNGLLGQYPNEYVQVIAVDPHSKFRVAELIVQRPGETGTLSTKATASARRSGNKVVNTASGGDVAGQIAALASQGCSFTAEHASTRRFKTQSWLGAGFVEGHSANQILANIQAIAAQFPNEYVQLIAVDPNSKTRAAEIIIQRPGNNAPVQTATATSSFSGGTKAAPSSNGFGGHSSGSLSGDVVSKVRSLLMQGYKIGTEHADKRRFRVKSWSSCGTIDSTQEAEVLRHLEGCLQEHSGEYVRMIGVDEAAKRRVLEEIIQRP
What is the function of this protein?
Beta-carboxysome assembly initiates when soluble RuBisCO is condensed into a liquid matrix in a pre-carboxysome by the RbcS-like domains of probably both forms of CcmM.  CcmN interacts with the N-terminus of full length CcmM, and then recruits the shell proteins (CcmK) via CcmN's encapsulation peptide.  Shell formation requires both CcmK proteins and CcmO.  CcmL caps the otherwise elongated carboxysome.  Once fully encapsulated carboxysomes are formed, they migrate within the cell probably via interactions with the cytoskeleton.
What are the official names of this protein?
Carboxysome assembly protein CcmM, CcmM70, M70, Carbon dioxide concentrating mechanism protein CcmM.
What is the protein family that this protein belongs to?
Belongs to the gamma-class carbonic anhydrase family.
What are the subcellular locations of this protein?
Carboxysome. Note=This cyanobacterium makes beta-type carboxysomes.
Protein: ACCA_YERPN
Sequence: MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGAWQIAQLARHPRRPYTLDYIANIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVLNDEELLNRRYQRLMNYGYC
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURL_LEUMM
Sequence: MTTNELSPEEVRDSKIYIEWGLTEQEYDLIVKELKRLPNFTETGIFSGMWSEHVSYKKSKPILRKFWSSNERVLQGPGEGAGILDIGDNQAVVFKAESHNHPSFVEPYEGAATGVGGILRDIFSMGAQPIAVLDSLRFGELDNAHTKHIVDGVIAGIAGYGNAIGIPTVGGEIGFDGVYAGNPLVNVMAVGLMDQNAMQVGQAKGIGNSIIYVGAKTGRDGINGASFASAEFSSAEKSDRSAVQVGDPFLEKLVMDATLQAIREHSDIIVGIQDMGAAGLLSSSSEMAAKAGMGIHLNLDMVPQRETGMTPYELMLSESQERMVLVVKKGEEQAIIDLFQSADLDAVIIGQVTDDGRYRLNFKNEVVADVPVDFLTHAPKQDLPMIEPARLANFTDEQFEPDMGNVKETILTLLAQPTIASKASLFRHFDSQVRADTAIKPGGDAALIRIRDTQKALAMTTDVNARYLYLNPRVGAKMAVAEAARNIVSTGAKPIGITDGLNFGSPDNPEVYYELDQAVAGINDVAKQLDTPIISGNVSLYNETDGQAIYPTPMIGMVGLLEDITKATRTAFQKAGDNIYLVGRTKDSFNGSEIQKMQTGHIAGQLFDFNDEDELAAQQVILDVTDQRLLNSAHDLSEGGLIVGLLESAFAGNLGFDISVDLADKYLFSETPSRFVVSVSPENRTTFESLAGDRVIKLGVVTADDTINITTTTSDIQLSLIETKKIYQESIAWKLNAE
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4772_CITK8
Sequence: MMIPWQELSSETLDNLIESFVLREGTDYGEHERSLEQKVADVKRQLQCGEAVLVWSELHETVNIMPREQFRE
What are the official names of this protein?
UPF0270 protein CKO_04772.
What is the protein family that this protein belongs to?
Belongs to the UPF0270 family.
Protein: KATG1_SHEAM
Sequence: MSNEGKCPVMHGGATSATQADNHWWPKALNLDILHQHDSKTNPMAPGFNYREALKGLDVEALKQDLKALMTDSQAWWPADWGHYGGLMIRMAWHSAGTYRIADGRGGGGHGAQRFAPLNSWPDNGNLDKARRLLWPIKQKYGNKVSWADLMILAGNMAYESMGLKTFGFAFGREDIWHPEKDTYWGAEKEWLAPSGGANSRYSGVRDLQNPLAAVMMGLIYVNPEGVDGNPDPLKTAQDMRVTFARMAMNDEETVALTAGGHTVGKAHGNGNAANLGPEPEAAPLEEQGFGWMNHQSRGIGRNTVTSGIEGAWTTHPTRWDNGYFHLLFSYDWALTKSPAGAWQWEPVNIREEDKPVDVEDPNIRSNPMMTDADMALKMDPDYRRIAERFFHDPDYFADTFARAWFKLTHRDMGPKSRYFGPDVPAEDLIWQDPVPKGNSQYDPEAVKARIAGTGLGAAELVATAWDSARTYRNSDKRGGANGARIRLLPQKDWVANEPARLARVLELLTPIASDMGVSIADTLVLGGNLGVELAAKAAGFNIKVPFIPGRGDASQAQTDIDSFEVLEPLADGFRNWQKQDFVVTPEEMLLDRAQLMGLSAPEMTVLIGGMRAMAVNHGGTTHGVLTDNPGSLSNDFFVNLTDMSYRWKPVANNLYEICDRASGQKKWTATRVDLVFGSNSVLRAYAEYYAQDDNKETFVKDFVTAWCKVMNADRFDA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 1, CP 1, Peroxidase/catalase 1.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: NUBCD_CITBB
Sequence: MSQGDDDKIPENVLLASLDDMINWGRANSLWPMFFGLSCCFVEMMTSFTSRYDVSRFGAEVLRGTPRESDLMVIAGTVFKKMAPSILRLYDQMAEPKWVISMGSCANSGGMYDVYSVVQGVNQILPVDLYIPGCPPRPESFLEGLMLLQQKIRSEERPTRPVLRMQGGTQGTVAPILVDGATKSRDTRGPGMEGIAIRGSAMQPPYFAAPRSDELWRPKQPRLPYPDFNLQAELQGAFAGQVVLDETACDMLTYRAPARLVPELLRHLKERKESPFRRLEDIACVDESCRRDREKYKDFTVNYHLTCFDTPGRIRIKTELEGSYPEAPSITSVFPVANWYEREAYDMFGIRFAGHPNLRRILMPPDWDGHPLRKEHPARATELPPYTAEDARRQKALPAGDFFDRVDDETLILNLGPQHPGTHGVIRFVLKLSGEEIVDMDSDIGYHHRAAEKTGERQNWHQYIPYTDRVDYLSGVQNNLAYLNSVETLCGIEIPDRAIYIRVMLCELFRIANHLVWLGTFASDLGAMTPVFYTFTDREKIFDIVEFITGGRMHPAWFRIGGVAEDLPEGWQEKVHSFLEWFPGRLAEYEKLLSGNPIFVARLKGVSAITVDTALEWGITGPNLRACDFAWDLRKKMPYGGYDRFEFEVATAQGGDCYARYQVRMEEMRQSLSIVRQAAAGMPGGRFISPDYRYTLPQKRDALEDIESLIHHFVNSTRGISPPKGECYAPIEGSKGEYGYFAVSDGLHTAYRMRIRTATFPHIQSLPVLSRGWLVSDFLAILGSLDFVLSDLDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B/C/D, NADH dehydrogenase I subunit B/C/D, NDH-1 subunit B/C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ASTA_PENMO
Sequence: MAVSSAVRMLSVACLVVSAAGMRRLGDCSSSADCGPGACCTIGFNRYSIPQCTPLGDLGDWCRVMNPPRELSLAYPNGLQVLLTDSYHGMCPCRPELACSRATSTCQLPQESTQHQEDNSLYKD
What is the function of this protein?
Cytokine directly involved in hematopoiesis.
What are the official names of this protein?
Astakine.
What is the protein family that this protein belongs to?
Belongs to the AVIT (prokineticin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: THIC_NITSB
Sequence: MRKEWVEKRKKDSVRTQMYYARQGIVTEEMEYVAKVEGLDPELIRKEVARGRMIIPANINHLHQKPMAIGIAAKCKINANIGSSALASDAAGEVEKVKVCQKYGADTIMDLSTGGDLDAIREEVIKHAEVPIGTVPIYQILHDCNNKIEDLTIDKMLEVIERQAQQGVSYFTIHAGFLLRFMPLVAKRKMGIVSRGGSLMAAWMMHYHKENPFYTAFDDILDICRKYDVSLSLGDSLRPGCLADASDDAQLEELKVLGELTLKAWDKDVQVMIEGPGHVPMNQIERNIKIERDYCHEAPFYVLGPLVTDIAAGYDHLASAIGAAMAGWYGASMLCYVTPKEHLGLPNAEDVREGIVAYKIAAHAADIARGRKGARDVDDAMSDARYKFDWNKQFELALDPDRAREYHDETLPQDVFKEAEFCSMCGPKFCSYKITQDILEKHGA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.