PharMolix/UniProtQA huggingface dataset:
Protein: PSB_METBU
Sequence: MDNDKHLKGTTTVGIVCTDGVVLATEQRATMGHFIASKTAKKIYQIDDLVGMTTAGSVGDAQQIVRIISVESKLFKMRRQESITIKGITTLLSNMLSGQRYYPLMVQLLIGGVDKNGPAIYSLDALGGNIEETRAVSTGSGSPMAYGVLEDRYTEDMTVVEGVDLAIRALHNAMKRDSASGENIDVVVITKDKYERLDPEAVMKKRELLN
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_EHRRG
Sequence: MNIDPVALKIGLLEIRWYSLAYIIGILFAYWYVQKIDKYKVFTPESYKSIISWWVTGMILGGRIGYILFYNLNFYMSFPIEMFKLWKGGMSFHGASLGLFCTMYIFCKKYKIKFLSAIDLCLCAVPVGIFLGRIANFINGELYGKVTNTRFGMIFQNSGDFFYRHPSQLYEAFFEGLLLFVVMNLLFFFTKVKSYQGMLFTIFMIWYGIVRFFIEFVREPDVQVGYILFNWITMGQLLSFIMVILGICILRLSRMSHNI
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARGC_STRM5
Sequence: MNDSTFTLGIVGARGHTGAELIKLVAAHPRLQLAFVSSRERAGQRLADHHPEFQGELRYENLDADAVAAKGVDAVILALPNGLAAPFVAALEAAKPDTVIVDLSADYRFDNAWYYGLPELTRGRYNGQKHISNPGCYATAMQLAIYPLLDLLAGPPQCFGVSGYSGAGTTPSDKNNVELLADNLMPYALTNHVHEREVSVQMGVAVEFMPHVAPHFRGITLTANLWLNRVQTREQIVERFQQAYAGEPLIEVVDEAPWVSRIAGRHGAQVGGFTLAPGGKRVVVVATLDNLLKGAASQAMQNLNLALGIDELTSIPH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH2_STRAW
Sequence: MNGSRIAAVGHYQPAKVLTNEDLASLVDTSDEWIRSRVGIRTRHFAGPDEPVDELAGHAAAKALASAGLAPADIDLVLVATSTAEDRSPNMAARVAARLGIPSPAAMDINVVCAGFTHALATADHAVRAGAATRALVIGADKMSAVTDWSDRTTCVLVGDGAGAAVVDACPEGAEPGIGPVLWGSVPEMGHAVRIEGTPPRFAQEGQSVYRWATTQLPAIARRACERAGLTPADLAGVVLHQANLRIIEPLAAKIGAVNAVVARDVVESGNTSAASIPLAFSKLVERGEISTGDPVLLFGFGGNLSYAGQVIRCP
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III 2, Beta-ketoacyl-ACP synthase III 2, KAS III 2, 3-oxoacyl-[acyl-carrier-protein] synthase 3 2, 3-oxoacyl-[acyl-carrier-protein] synthase III 2.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPX_SIVVG
Sequence: MASGRDPREARPGELEIWDLSREPWDEWLRDMLEDINQEAKMHFGRELLFQVWNYCQEEGERNRTPMLERAYKYYKLVQKALFVHFRCGCRRRQPFEPYEERRDGQGGGRAGRVPPGLD
What is the function of this protein?
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells.  Targets specific host proteins for degradation by the 26S proteasome.  Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1.  This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1.  In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription (By similarity).
What are the official names of this protein?
Protein Vpx, Viral protein X, X ORF protein.
What is the protein family that this protein belongs to?
Belongs to the lentivirus VPX protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Nuclear just after virion uncoating, or if expressed in the absence of unprocessed GAG.
Protein: CLPP_RICCK
Sequence: MSYVPIVIEQTSRGERAYDIYSRLLKERIIFVCSTVEDHMANLIVAQLLFLEAENPKKDIYMYINSPGGVVTAGLAIYDTMQYIKPKVATLCIGQACSMGSFLLCGGEKGMRYSLPHSRIMIHQPSGGYQGQATDIEIHAQETLKIKRLLNELYSKHTGQDVKHIEKSMERDNFMSPEEAKKFGIVDNIISSRNATGLLTK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_THEAB
Sequence: MNIEIIVPGKLSSHLQNVFDFYLKKLKRFANLSVTFTKLGGDVNRESKQVILRREKDEILNKVKNRRFILIDLHGKQMDSISFSKFVENEMLSGELLFVIGGPLGIDDELRKKASLKISLSKMTFTHEFTLVILLEQLFRAFKIINNEKYHY
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1309_HAES1
Sequence: MFGKGGLGNLMKQAQQMQERMQKMQEEIAQLEVTGEAGAGLIKVTINGAHNCRRIDIDPSLMEDDKEMLEDLIAAAFNDAVRRAEEMQKEKMASVTAGMSLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein HS_1309.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: Y573_CLOBK
Sequence: MSNMDFLPISKEDLKKRNIDVLDFIIVTGDAYVDHPSFGTAIIGRVLEREGFTVGIIAQPNWNNIEDFKKLGKPKYGFLVNSGNIDSMVNHYTASKKKRHDDFYSPGGKSGYRPDRAVIVYCNKIKEAFKDSPIIIGGIEASLRRFAHYDYWDNSVRRSILEDSSADLLIYGMGEKPIVQVSNLLRYGMKIDSIKNVRGTTYIEKDIFSLKDYIEIPSFEEVSTNKKSYAEAYKIQYYEQDSIRGKTLVQKHKERYVVQNPPQPPLSQEEMDEVYALPYARTYHPMYEAEGGIPAIKEVKFSITSHRGCYGSCSFCALTFHQGRVIQNRSQDSILKEANMMTNMKDFKGYIHDVGGPTANFRHRACKVQEKHGTCKNKQCVFPKACKNLIVDHKEYLSLLRKIRKIPNVKKVFIRSGIRFDYLMYDKNDEFFKELCEHHISGQLKVAPEHISDKVLNLMGKPTRNVYDSFVKKYYDINKKIHKNQFLVPYLMSSHPGSDLKAAIELAQYIKKMGYTPEQVQDFYPTPGSLSTTMYYTGINPLTEEKVYIPKDQKEKRMQRALLQFSIHDNYDLVKEALIKAHREDLIGNGPDCLIPYNKPYKKSHKKNNAKNNNNHYNKNNNKNKDISKKNKKNSLSKHKKRK
What are the official names of this protein?
UPF0313 protein CLD_0573.
What is the protein family that this protein belongs to?
Belongs to the UPF0313 family.
Protein: GBF3_ARATH
Sequence: MGNSSEEPKPPTKSDKPSSPPVDQTNVHVYPDWAAMQAYYGPRVAMPPYYNSAMAASGHPPPPYMWNPQHMMSPYGAPYAAVYPHGGGVYAHPGIPMGSLPQGQKDPPLTTPGTLLSIDTPTKSTGNTDNGLMKKLKEFDGLAMSLGNGNPENGADEHKRSRNSSETDGSTDGSDGNTTGADEPKLKRSREGTPTKDGKQLVQASSFHSVSPSSGDTGVKLIQGSGAILSPGVSANSNPFMSQSLAMVPPETWLQNERELKRERRKQSNRESARRSRLRKQAETEELARKVEALTAENMALRSELNQLNEKSDKLRGANATLLDKLKCSEPEKRVPANMLSRVKNSGAGDKNKNQGDNDSNSTSKLHQLLDTKPRAKAVAAG
What is the function of this protein?
Binds to the G-box motif (5'-CCACGTGG-3') of the rbcS-1A gene promoter.  G-box and G-box-like motifs are cis-acting elements defined in promoters of certain plant genes which are regulated by such diverse stimuli as light-induction or hormone control.
What are the official names of this protein?
G-box-binding factor 3, bZIP transcription factor 55, AtbZIP55.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
Protein: DPOD1_DROME
Sequence: MDGKRKFNGTSNGHAKKPRNPDDDEEMGFEAELAAFENSEDMDQTLLMGDGPENQTTSERWSRPPPPELDPSKHNLEFQQLDVENYLGQPLPGMPGAQIGPVPVVRMFGVTMEGNSVCCHVHGFCPYFYIEAPSQFEEHHCEKLQKALDQKVIADIRNNKDNVQEAVLMVELVEKLNIHGYNGDKKQRYIKISVTLPRFVAAASRLLKKEVIMSEIDFQDCRAFENNIDFDIRFMVDTDVVGCNWIELPMGHWRIRNSHSKPLPESRCQIEVDVAFDRFISHEPEGEWSKVAPFRILSFDIECAGRKGIFPEAKIDPVIQIANMVIRQGEREPFIRNVFTLNECAPIIGSQVLCHDKETQMLDKWSAFVREVDPDILTGYNINNFDFPYLLNRAAHLKVRNFEYLGRIKNIRSVIKEQMLQSKQMGRRENQYVNFEGRVPFDLLFVLLRDYKLRSYTLNAVSYHFLQEQKEDVHHSIITDLQNGDEQTRRRLAMYCLKDAYLPLRLLEKLMAIVNYMEMARVTGVPLESLLTRGQQIKVLSQLLRKAKTKGFIMPSYTSQGSDEQYEGATVIEPKRGYYADPISTLDFASLYPSIMMAHNLCYTTLVLGGTREKLRQQENLQDDQVERTPANNYFVKSEVRRGLLPEILESLLAARKRAKNDLKVETDPFKRKVLDGRQLALKISANSVYGFTGAQVGKLPCLEISGSVTAYGRTMIEMTKNEVESHYTQANGYENNAVVIYGDTDSVMVNFGVKTLERSMELGREAAELVSSKFVHPIKLEFEKVYYPYLLINKKRYAGLYFTRPDTYDKMDCKGIETVRRDNSPLVANLMNSCLQKLLIERDPDGAVAYVKQVIADLLCNRIDISHLVITKELAKTDYAAKQAHVELAAKMKKRDPGTAPKLGDRVPYVICAAAKNTPAYQKAEDPLYVLENSVPIDATYYLEQQLSKPLLRIFEPILGDNAESILLKGEHTRTRTVVTSKVGGLAGFMTKKTSCLGCKSLMPKGYEQACLCPHCEPRMSELYQKEVGAKRELEETFSRLWTECQRCQESLHEEVICSNRDCPIFYMRQKVRMDLDNQEKRVLRFGLAEW
What is the function of this protein?
As the catalytic component of the DNA polymerase delta complex, plays a crucial role in high fidelity genome replication, including lagging strand synthesis, DNA recombination and repair (By similarity).  Exhibits both DNA polymerase and 3'- to 5'-exonuclease activities (PubMed:7907087, PubMed:8415662, PubMed:1360647).  Required at the nucleus of rapidly dividing embryonic cells to activate genome replication during the earliest cell cycles (PubMed:31100062).  Likely to require the presence of accessory proteins PolD2 and PolD3 for full activity (PubMed:31100062).
What are the official names of this protein?
DNA polymerase delta catalytic subunit, 3'-5' exodeoxyribonuclease.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Note=In embryos, accumulates in the nucleus during interphase but disperses into the nucleoplasm at the onset of mitosis.
Protein: RSGA_ECOSM
Sequence: MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIVISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHERTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLNKIDLLDDEGMKFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILESMAQVKTRKNFSDTDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_RICRS
Sequence: MTTQKIVPTKSTDGSKLFRHQAKFVAGAMNINQIPNFSLPEIAFVGKSNVGKSSLINTICNNKNLAKVSNTAGRTRQINFFNLADKLIIVDLPGYGFANVPISVKEQWGVLISYYLRNSYNLRLVNLLIDSRRGIKENDKKVADLLLANKREFQIIFTKSDKVTDHKNLHDEAQNFLATLNYSCNVMYVSNRSKEGARELKASLAKCIKFQK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: MNMC_CAMJJ
Sequence: MKKAKLIFKDNTPFSLDFDDFYFNSKDGLNESKFVYTHSFEWKNQENFIIAESGFGIGLNFFLTLKRFLQTTPSKRPKKLFYISVEAFYIEKEQLREIYQKLGFYEEFKELLEQFLKFYPKAKEGIYRFYFEDCFLDLVFEDIAVLKELDFKADIWYLDGFSPNKNSQMFDGNLIFEVARLSKKNTQICTFSSASFLQKNLKKYGFRVEKTKGFRKREMIKAYLENELEFKDKEAYFSRTFSSLKNKKVAIIGAGISSAVLAYELSLRGFKIDVFEKHLELGKGASGNESGILSSLILKPKVNLGEFSELSFIEASRFYRQILDLKFKGVVEFAHNDLMQERFDTQRENVLFKISKNQAFLEEGGVIFPKNLVKNLFEKSKACIYFNHEFQAYKFENECFTLKFKNDIVKSDYAVLIYAMGADTKDFVFYDEMKLSKVRGQVTHLKPFLNTPFPLSSKAYICPVKDDLQVIGASYDRLDTSLESKEEDDKQNIENIAEFIDKNTKLEIIGSKVGFRSYSSDRFMIVGNAYDEVFYKEEYKALLWTKNKEQKLAKMSCNLYFNFAHGSRGFSTSVLAARYLCALINNEPLCLEKKYIHAIHPARFLIRKLKKGL
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAA_SORC5
Sequence: MDAVTTYEVFSAAQWAGLRAATPLPLTEGDLMVLRGLNERLSLDEVATIYLPLSRLLNLHVGAAQQLRRVKDTFLGRPVGRRPFVIGIAGSVAVGKSTTARVLQALLARWPDHPRVDLVTTDGFLYPNAVLASRAGLHRKGFPESYDLRRLVQFLADLEAGVEAIDVPVYSHATYDVVAGKAQTVRQPDIVILEGLNVLQGPERAAAIAVSDFFDLGIYVHADEADLERWYIERFLTLRATAFRDPSSYFHRYAAMGDDEARAFALQIWRTINGPNLTENILPTRARADVVLEKGPDHAVRAVHLRRL
What are the official names of this protein?
Pantothenate kinase, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_RICPR
Sequence: MHETIRVKIITPSSIAFEKQSKMVTMPGEDGMFGVLPHHVPMIVNLKAGLVQIYIYNIHNYENTYLISGGVTEITSHYINIVTEVAINVTNLSESEISTQRYELQKLLSHQH
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS1_CLOBL
Sequence: MKNVKIALTKGRLEKKAIEIFKTININTRELQDKGRKLIFNCENEEYNIELFLVKAKDVETYVEYGAADIGIVGKDTLMETNKEFYEVLDLNVGKCKFALAALPSFKLDQGYNRKKIATKYPNIAREYFRKKGMDVELIKIEGSVELGPIVGLADAIVDIVETGNTLRENGLVVVEDICEISARMIVNKASMKTKKDEIIKIIENVSEVIRQ
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAM3B_MOUSE
Sequence: MRPVATGIFKALVFIFSSLCAWYSGYLLAELIPDVPLSSTLYNIRSIGERPVLKAPAPKRQKCDHWSPCPPDTYAYRLLSGGGRDKYAKICFEDEVLIGEKTGNVARGINIAVVNYETGKVIATKYFDMYEGDNSGPMAKFIQSTPSKSLLFMVTHDDGSSKLKAQAKDAIEALGSKEIKNMKFRSSWVFVAAKGFELPSEIEREKINHSDQSRNRYAGWPAEIQIEGCIPKGLR
What is the function of this protein?
Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
What are the official names of this protein?
Protein FAM3B, Cytokine-like protein 2-21, Pancreatic-derived factor, PANDER.
What is the protein family that this protein belongs to?
Belongs to the FAM3 family.
What are the subcellular locations of this protein?
Secreted. Note=Present in insulin secretory granules and likely cosecreted with insulin.
Protein: AAEB_SALTY
Sequence: MGIFSIANQHIRFAVKLACAIVLALFIGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGMLRIIGTFIGCIAALIIIISMIRAPLLMILVCCVWAGFCTWISSLVRIENSYAWGLSGYTALIIVITIQTEPLLTPQFALERCSEIVIGIGCAILADLLFSPRSIKQEVDRELDSLLVAQYQLMQLCIKHGDSEEVDNAWGDLVRRTAALEGMRSNLNMESSRWVRANRRLKALNTLSLTLITQSCETYLIQNTRPELITDTFRELFETPVETVQDVHRQLKRMRRVIVWTGERETPVTLYSWVGAATRYLLLKRGVISNTKISATEEEILQGEPVVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGNGAMVMIAVVTSLAMRLPNPRMVCIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCLSLAVLGFFIGIEVQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCMLAFIVILLVRDKSKDRTGRVLLNQFVSAAVSAMTTNVVRRKENRLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSVFHRQLRRTADHVISAGSDDKRRRYFGQLLDELDIYQEKLRIWEAPPQVTEPVKRLTGMLHKYQNALTDS
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLMH_HELPY
Sequence: MRCVVYSIAKSSPLELVKIYQKQCRQFDCELELVDLFPKNTANAQKVSKKLAQKSYSLAFEPYLNPKAKNIALHPKAQRGDSFAFSKMLENHLNINFFIAGAYGFEENFLKDCQAWSLSEMTFSHEVAKIVLCEQIYRALSIIFKHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_MARMS
Sequence: MSEYSLFTSESVSEGHPDKIADQVSDAILDAILAEDPEARVACETLVKTGMVLVAGEVRTNAWVDIEEIARGVIREIGYNSSDMGFDWESCAVMNAIGKQSADIAVGVDEAGEHEQGAGDQGLMFGFATNETDVLMPAPITYAHRLVQRQAEVRKNGTLDFLRPDAKSQVTFRYDENGKPCAIDAVVLSTQHSASVKQADLREAVMEEIIKPVLPAEWLSKETKYFINPTGQFIIGGPVGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLADKCEIQISYAIGVAEPTSISINTFGTGKVSDAVISQLVREHFELRPAGLIKMLDLKRPIYLPTAAYGHFGREGENFTWEKTDKADALRKAAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAGT4_ARATH
Sequence: MNLGDPDFVDVSKVISDMLSTNFAQGLKKKINDNKTFDPNYYGGRWDQINDHGTSHLSIIDSERNVVSLTSTINSYFGALMLSPSTGIVLNNEMDDFSIPMKSSSNLTVPPPAPANFIRPGKRPLSSMTPTIVLKDGKVKASVGASGGLYIIAGTTEVFLNYFFLKMDPLSSVLAPRIYHQLIPNIVSYEN
What are the official names of this protein?
Putative inactive glutathione hydrolase 4, Gamma-glutamyltranspeptidase 3, Putative inactive gamma-glutamyltranspeptidase 4.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
Protein: MNMA_MOOTA
Sequence: MVAMSGGVDSSTAAALLKEAGYEVIGVTLALWPEDTPPPPGETGCCSLKAVDDARRVANILDIPYYVLNFRDLFEREVIDYFIASYLEGETPNPCIACNRRIKFGALLAKARALGIDYIATGHYARRWYDKEKGRYLLARGRDAGKDQSYALYTFTQEQLAHTLLPLGDYTKVEVREIAARYGLPVARKAESQEICFVTEGDYRDYIQSRAREKIKPGPILDTRGRVLGQHRGLPFYTIGQRKGLGLALGKPCFVVALDPERNAVIVGDKEDLERRVLYARDNNYILWGELPGKARVTARIRYRAPEAAATWHPLAGGRARLEFDEPQRAITPGQAVVYYQGDLVVGGGTIESVAQI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_GOSHI
Sequence: MKINPTTSVPGVSTLEKENLGRISQIIGPVLDVAFPPGKMPNIYNALVVKGQDTAGQQINVTCEVQQLLGNNRVRAVAMSATDGLTRGMEVIDTGAALSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHKSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGTLQERITSTKEGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQRVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGELDGLPEQAFYLVGNIDEATAKATNLEMESKLKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, chloroplastic, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: Y1375_MYCTU
Sequence: MTGRRLARFPAFRAGVAQDDDVGSTLSQGSTTGVLSGPNWSYWPSRVLGSADPTTIAHRHGTHRITSPDETWLALQPFLAPAGITGVADVTWLDCLGIPTVQAVRPASLTLSVSQGKAASYRAAQVSAVMESLEGWHAENVTADLWSATARDLEADLTYDPAQLRHRPGSLYHAGVKLDWMVATTLLTGRRTWVPWTAVLVNVATRDCWEPPMFEMDTTGLASGNCYDEATLHALYEVMERHSVAAAVAGETMFEVPTDDVAGSDSAHLVEMIRDAGDDVDLARIDVWDGYYCFAAELTSATLEVTFGGFGLHHDPNVALSRAITEAAQSRITAISGAREDLPSAIYHRFGRVHTYAKARKTSLRLNRARPTPWRVPDVDSLPELVASAATAVANRSGTEPLAVVCDFADACVPVVKVLAPGLVLSSASPMRTPLQEAE
What are the official names of this protein?
Uncharacterized protein Rv1375.
Protein: FOXO_DROGR
Sequence: MDGFVQEWSNLPRSDNGLHMDQLVGELPTDGGFEPQTRARSNTWPCPRPENFVEPVDELDSTKASNQQLADPQQAMQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVAYFKDKGDSNSSAGWKNSIRHNLSLHSRFMRVQNEGTGKSSWWMLNPDAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGAVGLNDATPSPSSSVSEGLDHFPESPLHSGGFQLSPDFRQRASSNASSCGRLSPIRALDLEPDWGYSVDYQNTTMTQAQAQALDQLTGSMADELKLQNDMLQQQGFSAASGLPTQPPPPYQQQQQQQQQQAQQQSQLPQGYTLNGPVSAPGYNTLQPQAQQQQQQQQQQQQQQQQPQCLLHRSLNCGCLHSTRDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNSILLDAASDNGSLLVQQQQQQQQQQQQQQQQQQQLSSGLEGQCLEALNSEQIDEFNLENFQGGLECNVEELLQQEMIYDGLLDINIPLPAVNTNATNVILTNNSTNNSSSGCNISAGVQLSCSQLQAELQLQQQQQQQQQQQQQQQQQQQQQQQQLLLSNNNNNNNNSLELATQTATRVQYTQPSVVTSPPSWVH
What is the function of this protein?
Transcription factor involved in the regulation of the insulin signaling pathway.  Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR.  Involved in negative regulation of the cell cycle, modulating cell growth and proliferation.  In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.  Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging.  Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis (By similarity).
What are the official names of this protein?
Forkhead box protein O.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation (By similarity).