PharMolix/UniProtQA huggingface dataset:
Protein: RIMM_MYCS2
Sequence: MDLVVGRVVKAHGISGEVVVEIRTDDPEARFAPGAVLRGRPRSGAEREYTIESVRAHGGRLLVRLAGVADRNGADELRGTVFLVDTAELPAIDDPDEFYDHELEGMRVVTVDDAPVGKVAEVLHTAGGEILAVKADEGGREILVPFVGAIVTSVSRQNATIVIDPPEGLLDLA
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_LEGPL
Sequence: MSTISAALVMQLRERTGAGMMECKKFLIATNGDIEQAIIEMRKAGQAKADKKADRVAAEGIIVIARSSDERTAVMLEINSETDFVARDENFTNFANAVADIALTSLPKNIEDLSNQALSSGATVEQARQELVAKIGENIKLRRLEKMHCDGVIGYYLHGSRIGVMVALKNGSEALAKDIAMHVAASKPMVVSRDQVPAEAIENEREIFTAQAKESGKPQEIIDKMIDGRINKFIDEVSLLGQPYVKDPNIKVGQLLKEKNAEVISFVRYEVGEGIEKKEDNFVEEVMAQVRT
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_PROA2
Sequence: MKTTAWTIGDIHGIGPEIILKTFDESLRSTGQPEEKPIVIGSAEALLYYSKRLGLSIDIRTIDAPEKAAAYPQGVLPVISVGEPSSPLQPGTISAEAGRLSMLAIEKAANLCLEGRCAAMVTAPIHKEAVARAGYPHTGHTDFLADLCATDNPTMLFRDPVSGLMVALATIHVALHRVPELIRSMDMSAFFSNLNRSLQSDFRIEQPRIAVLGLNPHASDGGVMGREEKEIILPCIDALADRQNIEGPFAADGFFGSGKYRNYDVTVAMYHDQGLLPFKVLAFDTGINVTLGLPLVRTSPDHGTSFDIAGQGRASHRSFSEAAKLAWEIAFNRLMEHS
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_ECO5E
Sequence: MGLSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSS_SALOF
Sequence: MSSISINIAMPLNSLHNFERKPSKAWSTSCTAPAARLRASSSLQQEKPHQIRRSGDYQPSLWDFNYIQSLNTPYKEQRHFNRQAELIMQVRMLLKVKMEAIQQLELIDDLQYLGLSYFFQDEIKQILSSIHNEPRYFHNNDLYFTALGFRILRQHGFNVSEDVFDCFKIEKCSDFNANLAQDTKGMLQLYEASFLLREGEDTLELARRFSTRSLREKFDEGGDEIDEDLSSWIRHSLDLPLHWRVQGLEARWFLDAYARRPDMNPLIFKLAKLNFNIVQATYQEELKDISRWWNSSCLAEKLPFVRDRIVECFFWAIAAFEPHQYSYQRKMAAVIITFITIIDDVYDVYGTIEELELLTDMIRRWDNKSISQLPYYMQVCYLALYNFVSERAYDILKDQHFNSIPYLQRSWVSLVEGYLKEAYWYYNGYKPSLEEYLNNAKISISAPTIISQLYFTLANSIDETAIESLYQYHNILYLSGTILRLADDLGTSQHELERGDVPKAIQCYMNDTNASEREAVEHVKFLIREAWKEMNTVTTASDCPFTDDLVAAAANLARAAQFIYLDGDGHGVQHSEIHQQMGGLLFQPYV
What is the function of this protein?
Catalyzes the formation of the (-)-3-isothujone precursor sabinene from geranyl diphosphate.  The enzyme also produces significant amounts of gamma-terpinene, terpinolene and limonene.
What are the official names of this protein?
(+)-sabinene synthase, chloroplastic, SSS.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PRP17_SCHPO
Sequence: MLVANYSSDSEEQENSQSPNIQPLLHTENLAPAVVDNVKDDLIVSKGGNSRELARNVPVNEMVQPALGPANPFVTKEQDSIKNSITGYAEREYVPNFVFNQEYYANTHAIYGKRNFDDNEATTSTDLKRKSQKIKERREDPGDPSILEGDGAYKGPWAGYGSEQSSSPLEYSEYEEVESLDVKSEKDTESNNLGQNELLKEQLATPEVETHRSKEETILHKDRLFDYQNRSYMHVPNDVGINLSEEPGEQTCYIPKKHIFTWKGHTKGISCLRFFPISGHLLLSGSMDNQIKIWEVYHDRSLLRTFQGHARPIRDLSFSQDGRSFLSTSFDKTIKLWDTELGKCLNCFNSDRLTNCVKFQVDPDKPNEFLAGTADKRILQFDIRSPDIVQAYDHHLGGINSITFLENGKRFVTTSDDSSMRFWEYGTPVPIKFVADIAMHSMPRVALRPNGKSIACQSLDNCIYVYSAYEKYRQNKKKVFKGYSCSGYSLEVGFSPDGRFVFSGDSSGNACFWDWKTCKLMAKLPAHSGPVQSMAFHPQETSKVATSSIVDGSIKYWD
What is the function of this protein?
Functions in the second step of pre-mRNA splicing.  Involved in splicing intron which are longer than 200 nucleotides.
What are the official names of this protein?
Pre-mRNA-processing factor 17.
Protein: CAH_PSEUX
Sequence: MTVVDIVKRTTSSPDDTALVKTLADAGYSTADVVALVAKTEGNGCVNDFSRTLADHTWDAVLPADAVTVFSGGTEGVLSPHASAFVGTDRPAAPEGALVAAVGRTASIPIADLGRAGQVRAVAARVRELCADAALEPGDVHLVLVKCPLLTTESISRCLADGVEPATRDTLRSMAMSRAASALGVAVALGEISEPDAAAALRGEADVWSSVASISSGAELDDCHILVLGNSPAAHGPLRAVHGVMRDAMDARTVLDLLDRVSADGGEVVQVLAKAEADPSGSIRGRRHTMLTDSDLSSTRHARAAVGGLLAGLVGDSAIYVSGGAEHQGPPGGGPVTVVYRVAS
What is the function of this protein?
Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine.  Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.
What are the official names of this protein?
Cyanuric acid amidohydrolase, CAH.
What is the protein family that this protein belongs to?
Belongs to the cyclic amide hydrolase (CyAH) family.
Protein: HIS3_PSEPK
Sequence: MKDWLDEIKWNSDGLVPAIAQDHKTGRVLMMAWMNRESLALTAAEQRAIYWSRSRGKLWRKGEESGHVQKLHELRLDCDADVIILMVEQLGHIACHTGRESCFYRVYEDGQWKIVDPVLKDPDAIYSAGH
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAMT_MAGSA
Sequence: MSMEAPRRGRRWVSLGMIALLAAIGLGLYWDQLSTPSGITPATSPRRAEGLLLGRLPLPMEPSLLSPLERLLEPPLRYKLMTIRHIPPVKPGTGMPHPYVGDCIQCHLMVGGPAAGSQFKTPYGAVLENLSRVRKLGPPILPTSRQPHPPAGRCIKCHDIVVKVPVDKKGGMRWQL
What is the function of this protein?
May play a role in magnetite crystal maturation (Probable).  May transfer electrons to balance the Fe(2+)-Fe(3+) ratio during magnetite formation (Probable).
What are the official names of this protein?
Magnetosome protein MamT, Magnetochrome MamT.
What is the protein family that this protein belongs to?
Belongs to the magnetosome MamT family.
What are the subcellular locations of this protein?
Magnetosome membrane; Single-pass membrane protein.
Protein: GSA1_STAAU
Sequence: MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGSKIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVIDRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVATLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGNDIAGVIVEPVAGNMGVVPPIEGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGYFGVTPDLTCLGKVIGGGLPVGAFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILEDGLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVFLPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 1, GSA 1, Glutamate-1-semialdehyde aminotransferase 1, GSA-AT 1.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_SALAR
Sequence: MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANIGDSYVILKDGEAWLFGANFTPMAVASTHVVCDPTRTRKLLLNQRELDSLYGRINREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDLKEREWQLDKARIMKHAGR
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: RS4_PARL1
Sequence: MTKRQESKYKIDRRMGENIWGRPKSPVNRREYGPGQHGQRRKGKLSDYGVQLRAKQKLKGFYGNISEKQFRGIYKEANRLRGDTSEILIGLLERRLDAVVYRAKFVMTPFAARQFVGHGHILVNGKRVNVPSYRVREGDVIEVREKSKQLAIVLEASQSAERDTPDYIEVDHDKMVAKFVRIPAFSDVPYAAHMEPNLVIEFYSRS
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RHMD_BURCH
Sequence: MSMPTIRAVRALTVRGGGADYHDQDAGHWIDDHIATPMSRYPEYRQSRQSFGINVLGTLVIEVEASDGTVGFAVTTGGEIGAFIVERHLARFIEGQRVTDIEKMWDQMFHATLYYGRKGVVLNAISGVDLALWDLLAKVRREPVHQLLGGKVRDELEFYATGARPDLAKEMGFIGGKLPLHHGPAEGEAGLRRNLDALADMRSRVGADFWLMLDCWMSLDVPYATRLAHEAHALGLKWIEECLPPDDYWGYAKLRRDVPRGMLVTTGEHEATRWGFRMLLEMECCDIIQPDVGWCGGLTELMRISALADARGVLVIPHGSSVYSYHFVTTRHNSPFAEFLMMAPQADRVVPMFDPLLLDEPVPVGGRMKVPDTPGFGVRLNPDVRMQRPYEH
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: LHTL7_ARATH
Sequence: MSIALGNLFDLESQESGGSPLFMSPAPSTDPQPISGEKNGGDGGRIPVEEWLPITESRKGNVYTATFHLLCSGIGLQVILLPAAFAALGWVWGTIILTVGFVWKLYTTWLLVQLHEAVPGIRISRYVRLAIASFGVKLGKLLGIFPVMYLSGGACTILVITGGKSIQQLLQIMSDDNTAPLTSVQCFLVFSCIAMIMSQFPNLNSLFGVSLIGAFMGIAYCTVIWILPVASDSQRTQVSVSYATMDKSFVHIFNAIGLIALVYRGNNLVLEIQGTLPSDSKNPSCKTMWRAVMISHALVAICMFPLTFAVYWAYGDKIPATGGPVGNYLKLYTQEHSKRAACFIHLTFIFSCLCSYPINLMPACDNIEMVYITKKKKPASIIVRMMLRVFLSLVCFTIAVGFPFLPYLAVLIGAIALLVTFTYPCFMWISIKKPQRKSPMWLFNVLVGCLGASLSVLLLVASAMRLAQKGLHANFFRP
What is the function of this protein?
Amino acid transporter.
What are the official names of this protein?
Lysine histidine transporter-like 7.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family. Amino acid/auxin permease (AAAP) (TC 2.A.18.2) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VA722_ARATH
Sequence: MAQQSLIYSFVARGTVILVEFTDFKGNFTSIAAQCLQKLPSSNNKFTYNCDGHTFNYLVENGFTYCVVAVDSAGRQIPMAFLERVKEDFNKRYGGGKAATAQANSLNKEFGSKLKEHMQYCMDHPDEISKLAKVKAQVSEVKGVMMENIEKVLDRGEKIELLVDKTENLRSQAQDFRTQGTQMRRKMWFQNMKIKLIVLAIIIALILIIILSICGGFNCGK
What is the function of this protein?
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
What are the official names of this protein?
Vesicle-associated membrane protein 722, AtVAMP722, Synaptobrevin-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein. Early endosome membrane; Single-pass type IV membrane protein.
Protein: NUF2_ARATH
Sequence: MSAYEYPRLSRSDIITALKDAQIASVTETDLKTPTSDFVSELYTRILIYLDALDEEEKGQVDFEALEQLENPDHHATSMQAMKLYCKVKDMLEMLDCPLPISFKDLLRPESSRTEFFISALLNYGLYKDSKMDLIRPKAEELGLLDEQRKQCEAKVAQLNAEIGEFDEAVERDLPFVQELEANIEQLNKKILELNNQQMSLRATFQKMREKSTQMDNEISKAEFDLVETVQENANLRSQIVQSPDKLQGALEEKKLVLGETKKAEQSAMVTFQEKAAILEVFEKALKKILKSSSQLQLINEQVTNAKTVEKEFKALKDKLSEDGVAYKSLEAKVVERERIVEQLNESLKQLEKEKAVMFDDWTKQLNELKVEVESRRRELETRQTNVESVVAMVDDNTAKTNQVRQSGEAKVKKLAAKYEEIVKQFHEYTVSFDAFLPSL
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity to ensure proper cell division.
What are the official names of this protein?
Kinetochore protein NUF2 homolog.
What is the protein family that this protein belongs to?
Belongs to the NUF2 family.
What are the subcellular locations of this protein?
Chromosome, centromere.
Protein: RUVA_RICCN
Sequence: MIGQLSGKVDSQGDDYVIIDVNGVGYLVYASGKTLGKLAEGEFYKLFIETHVREEHIHLYGFLTLEEKIFFNLLQSVNGIGTRMALFILSSLTPSDIQIAVNNEDKNIFKAISGVGAKLAERIVLELKGKVAKISSGSAIIKESLNIKNITPVASNEVIKALVNLGFSRFEAQNAVQGIITQNPEISIDELIKTALKNRNSNF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: EFPL_SHESH
Sequence: MPKASEVKKNTAIEFNNNVYLIRDIERSVPQGRSGGSLYRMRMYDVATGSKLDHTFKADEMINLADLSRHEVSFSYIDGDEYVFMDIADYTPYHFNKDSIADEILFINEETQGLQVLTVDGTPVAIELPANVELVIVETDPSIKGASASARTKPAILSTGLSVQVPEYIANGEKIKINTAEHKFMSRADSK
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: SSRP_BURMS
Sequence: MSIIDNRKAFFDYHIEERYEAGLVLEGWEVKALRAGRGQIKEGYVVVKHAEIFLIGTHISPLPEASTHIKPDPVRTRKLLLHRDEIKKLIGKVEQRGYTLVPLNFHYKGGRVKCEIGLAKGKKLHDKRETEKKRDWEREKARIMRSAT
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: MURC_RICCK
Sequence: MLLLELKKINQTLETIHFIGIGGVGMSGIAEILHNLGYKVQGSDLVENYNTKRLESYGIKIFLGHVPQNITNVSYVVISSAINPDNPEIQEALERKIPIIRRAEMLAELMRLKCSVAVSGSHGKTTTTSLVACLFEAAGLCPTVINGGIINNRSTNAYLGSSNYLIAEADESDATFIHIPSTIAIITNIDPEHLDYYKDFATLISAFRSFIINLPFYGFAVCCIDHKIVRKLVDDITERKIVTYGIDSADAHIIAFNINTDIASSTFDVKISLPNVLGTTIIEKITIPIPGRHNILNSLAAIAVGIELDFGIKAIKNGFNNFKGVKRRFTKVAEYNMASIIDDYAHHPEEIKATLATAKNIANKQNGKVIAIFQPHRYSRMQHLFDDFMLCFADADILYITDIYAAGENPIEGITGQSLVDKITKNKYHDQANFLATLDDAVGVIIDNAVSGDVIIMMGAGNISSFANELPKKFGNL
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S2542_HUMAN
Sequence: MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQILLRHLQS
What is the function of this protein?
Mitochondrial carrier mediating the transport of coenzyme A (CoA) in mitochondria in exchange for intramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate.
What are the official names of this protein?
Mitochondrial coenzyme A transporter SLC25A42, Solute carrier family 25 member 42.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
Protein: TM141_DANRE
Sequence: MVNIGLSKVDDAIVAKHPGLQQYVACQSYAFMKGTASFILGTVGIFFGQRALQKIIKYPLQWNLFVSIVSSSVFSYSVTRWETMKCSDVWLFLETGNIPDRNSDKEEPETSADSTTTQHEDVLE
What are the official names of this protein?
Transmembrane protein 141.
What is the protein family that this protein belongs to?
Belongs to the TMEM141 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: UROM_BOVIN
Sequence: MKCLFSPNFMWMAAVVTSWVIIPAATDTSSAKSCSECHSNATCTVDGAATTCACQEGFTGDGLECVDLDECAVLGAHNCSATKSCVNTLGSYTCVCPEGFLLSSELGCEDVDECAEPGLSRCHALATCINGEGNYSCVCPAGYLGDGRHCECSPGSCGPGLDCVREGDALVCVDPCQVHRILDEYWRSTEYGSGYICDVSLGGWYRFVGQAGVRLPETCVPVLHCNTAAPMWLNGTHPSSDEGIVNRVACAHWSGDCCLWDAPIQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECRVDEDCKSDNGEWHCQCKQDFNVTDLSLLERRLECGVDDIKLSLSKCQLKSLGFEKVFMYLHDSQCSGFTERGDRDWMSVVTPARDGPCGTVMTRNETHATYSNTLYLADEIIIRDLNIRINFACSYPLDMKVSLKTSLQPMVSALNISMGGTGTFTVRMALFQSPAYTQPYQGSSVTLSTEAFLYVGTMLDGGDLSRFVLLMTNCYATPSSNATDPLKYFIIQDRCPRAADSTIQVEENGESPQGRFSVQMFRFAGNYDLVYLHCEVYLCDTVNEKCRPTCPETRFRSGSIIDQTRVLNLGPITRKGGQAAMSRAAPSSLGLLQVWLPLLLSATLTLMSP
What is the function of this protein?
In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals.  Protects against urinary tract infections by binding to type 1 fimbriated E. coli.  Binds to bacterial adhesin fimH which mediates the stable formation of bacterial aggregates, prevents the binding of E. coli to uroplakins UPK1A and UPK1B which act as urothelial receptors for type I fimbriae, and allows for pathogen clearance through micturation.  Also promotes aggregation of other bacteria including K. pneumoniae, P. aeruginosa and S. mitis and so may also protect against other uropathogens.
What are the official names of this protein?
Uromodulin, Tamm-Horsfall urinary glycoprotein, THP.
What are the subcellular locations of this protein?
Apical cell membrane; Lipid-anchor, GPI-anchor. Basolateral cell membrane; Lipid-anchor, GPI-anchor. Cell projection, cilium membrane. Note=Only a small fraction sorts to the basolateral pole of tubular epithelial cells compared to apical localization. Secreted into urine after cleavage. Colocalizes with NPHP1 and KIF3A. SUBCELLULAR LOCATION: [Uromodulin, secreted form]: Secreted. Note=Detected in urine.
Protein: DOC2B_MOUSE
Sequence: MTLRRRGEKATISIQEHMAIDVCPGPIRPIKQISDYFPRFPRGLPPTAAPRAPAPPDAPARSPAASASPRSPSDGARDDDEDVDQLFGAYGASPGPSPGPSPARPPAKPPEDEPDVDGYESDDCTALGTLDFSLLYDQENNALHCTISKAKGLKPMDHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPSWNETLTYYGITDEDMVRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTFSICLEKQLPVDKAEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLKPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKTLEVTVWDYDIGKSNDFIGGVVLGINAKGERLKHWFDCLKNKDKRIERWHTLTNELPGAVLSD
What is the function of this protein?
Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes.  Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion.  Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells.  Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.
What are the official names of this protein?
Double C2-like domain-containing protein beta, Doc2-beta.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule. Cell membrane; Peripheral membrane protein. Note=Translocates to the plasma membrane in a calcium-dependent manner.
Protein: O10C1_HUMAN
Sequence: MSANTSMVTEFLLLGFSHLADLQGLLFSVFLTIYLLTVAGNFLIVVLVSTDAALQSPMYFFLRTLSALEIGYTSVTVPLLLHHLLTGRRHISRSGCALQMFFFLFFGATECCLLAAMAYDRYAAICEPLRYPLLLSHRVCLQLAGSAWACGVLVGLGHTPFIFSLPFCGPNTIPQFFCEIQPVLQLVCGDTSLNELQIILATALLILCPFGLILGSYGRILVTIFRIPSVAGRRKAFSTCSSHLIMVSLFYGTALFIYIRPKASYDPATDPLVSLFYAVVTPILNPIIYSLRNTEVKAALKRTIQKTVPMEI
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 10C1, Hs6M1-17, Olfactory receptor 10C2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SAHH1_ARATH
Sequence: MALLVEKTSSGREYKVKDMSQADFGRLELELAEVEMPGLMACRTEFGPSQPFKGARITGSLHMTIQTAVLIETLTALGAEVRWCSCNIFSTQDHAAAAIARDSAAVFAWKGETLQEYWWCTERALDWGPGGGPDLIVDDGGDATLLIHEGVKAEEIFEKTGQVPDPTSTDNPEFQIVLSIIKEGLQVDPKKYHKMKERLVGVSEETTTGVKRLYQMQQNGTLLFPAINVNDSVTKSKFDNLYGCRHSLPDGLMRATDVMIAGKVAVICGYGDVGKGCAAAMKTAGARVIVTEIDPICALQALMEGLQVLTLEDVVSEADIFVTTTGNKDIIMVDHMRKMKNNAIVCNIGHFDNEIDMLGLETYPGVKRITIKPQTDRWVFPETKAGIIVLAEGRLMNLGCATGHPSFVMSCSFTNQVIAQLELWNEKASGKYEKKVYVLPKHLDEKVALLHLGKLGARLTKLSKDQSDYVSIPIEGPYKPPHYRY
What is the function of this protein?
Essential protein during embryogenesis (PubMed:15266054).  Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine (PubMed:15659630).  Required for DNA methylation-dependent gene silencing (PubMed:15659630).
What are the official names of this protein?
Adenosylhomocysteinase 1, AdoHcyase 1, Protein EMBRYO DEFECTIVE 1395, Protein HOMOLOGY-DEPENDENT GENE SILENCING 1, S-adenosyl-L-homocysteine hydrolase 1, SAH hydrolase 1.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
Protein: ATPD_STREI
Sequence: MDKKTQALVEQYAKSLVEIAIEKDSLAELQSETEALLSVFEETNLADFLSSLVVSRDEKVKLVRLLQESSSVYMNNFLEVILQNEREAFLKAILEGVQKDFVIATNQHDIVVTTAVALTDEQKERILALVAEKFGVKAGKLVENIDESILGGFVINVNNKVIDTSIRRQLQEFKMNLK
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.