PharMolix/UniProtQA huggingface dataset:
Protein: COBQ_THEAC
Sequence: MIQVLGTSSGSGKTTIAMALSRIFFRSGYRVAPFKAVNMSLNSVIVEGEYEIARAQWLQAKAANTEPTRFMNPILLKPEGMGASQVIMLGKSLGKKTIPEYYEFIMNDGKRVIREAIDRISDDYDLIIAEGAGSPAEINLLDRDMANIYVSSIYNTPAILVGDIDRGGVFASIYGTLSLMPRPDLVRWIMINKMRGDASLLEPGLKKLENLTGKRVIGVVPYSENRLPGEDSFDYDHPRARGSKITIVRYPFMENYSDLDPLVYTSTGYNYVTAENASDLSDADLIVLPGSKNVFADLEYMRKNGIDKIIIENAGRAKILGICGGYQMLGQRITMGEISADGLGLLRAKTNYERTKTTRSVRYRVDNTLMSGTWEEGYEIHYGAVISLGGERMNETDKGPEGNVDANRLVFGTNIHGILANRSVFRFMTGRDIGEPEEYLRSEIDRFADVVKSSIDVADLIEYASSRE
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity).
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: MTRC_METTM
Sequence: MSVAAGGPAGAAIPESRLMALGILGGLAGIYASAVNPVIGPVLASLGAVCAIVWGADAIRRVASYGLGTGVPSIGYMSVSIGIVGVVAGLASVFVVPAIAVPVVALILAMILGVVVAVLGKKIVKMKIPILEKCTAEISGAAALSVLGFSAAIAGSYTLQTMLTSVITTGFIGLLFILNTMAIQHPFNACLGPNENQTRTLKLAASTGFISMAIVGLLGIGLNPSWWLVSLIGALCWIVAFRAFVSASFEEAASVKWSGLWPKEEEH
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit C, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit C.
What is the protein family that this protein belongs to?
Belongs to the MtrC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNJ39_ARATH
Sequence: MATHSSRSENKDAGEEDELRRRNPYEVLGIPSNSTDQEIKSAYRRMALRYHPDKNPDDPVAAEMFKEVTFAYEVLSDPENRRLYDTTGSEAVGPENEDLELDLSSLGAVNTIFAALFNKLGVQIKTTVSANLLGEALNGTVTTLPLMVGQVVSRKVEKQSAHFYSVTLTEEEAQDGLICKVHSSAKNKFKLLYFDQVENGGLSLALQEDSRKTGKLSTAGLYFFGFPVYRFDHRVNSRALSRDPETGFFKRLDAFQPFEITELKAGSHVFAVYGDNFFKSVSYTLEIFSSAPFGNEKESLRSTEAQIVSKRTELLKFEAEYHEVFAQFTEMASKCTGEVQEIDELLKRRNEICAAYTIFPPTKQGSSKSRSWSKKKSSLLMEPREEGEVAVREEGGVKKKKWYNIQLRQDKKKN
What is the function of this protein?
Plays a continuous role in plant development probably in the structural organization of compartments (By similarity).  Seems to be involved in early gravitropic signal transduction within the gravity-perceiving cells (statocytes).
What are the official names of this protein?
Chaperone protein dnaJ 39, AtDjC39, AtJ39, Protein ARG1-LIKE 2, AtARL2.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family. C/III subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: Y1257_STRZT
Sequence: MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEVSRFLEEHASFSFNLGDFDAIWQEYLEH
What are the official names of this protein?
UPF0346 protein SPT_1257.
What is the protein family that this protein belongs to?
Belongs to the UPF0346 family.
Protein: AUHM_MOUSE
Sequence: MAAAAPGALGALRTGRVRLVAACCARLGPAAWARGTAPRRGYSSEVKTEDELRVRHLEEENRGIVVLGINRAYGKNALSKNLLKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMHSSEVGPFVSKIRSVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGQEAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIEEACYAQTISTKDRLEGLLAFKEKRPPRYKGE
What is the function of this protein?
Catalyzes the fifth step in the leucine degradation pathway, the reversible hydration of 3-methylglutaconyl-CoA (3-MG-CoA) to 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA).  Can catalyze the reverse reaction but at a much lower rate in vitro.  HMG-CoA is then quickly degraded by another enzyme (such as HMG-CoA lyase) to give acetyl-CoA and acetoacetate.  Uses other substrates such as (2E)-glutaconyl-CoA efficiently in vitro, and to a lesser extent 3-methylcrotonyl-CoA (3-methyl-(2E)-butenoyl-CoA), crotonyl-CoA ((2E)-butenoyl-CoA) and 3-hydroxybutanoyl-CoA (the missing carboxylate reduces affinity to the active site) (By similarity).  Originally it was identified as an RNA-binding protein as it binds to AU-rich elements (AREs) in vitro.  AREs direct rapid RNA degradation and mRNA deadenylation (PubMed:10072761).  Might have itaconyl-CoA hydratase activity, converting itaconyl-CoA into citramalyl-CoA in the C5-dicarboxylate catabolism pathway.  The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, an antimicrobial metabolite and immunomodulator produced by macrophages during certain infections, that can act as a vitamin B12-poisoning metabolite (By similarity).
What are the official names of this protein?
Methylglutaconyl-CoA hydratase, mitochondrial, 3-MG-CoA hydratase, AU-specific RNA-binding enoyl-CoA hydratase, AU-binding enoyl-CoA hydratase, muAUH, Itaconyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUOB2_ANASK
Sequence: MASELDGLPVIATRREEAEGFLQGLVSKSLGWARKYSLFTYPFVTACCGMEYMTMASARYDSDRFGAAMPRFSPRQADLLMVVGTVNCKQAPILQRVYEQMADPKWVMAFGVCASSGGFYDNYATVQGIDRVIPVDVYVPGCPPRPEQVLDGIMLLQKKIQNQSHKLIDRKPLPVISGGAGR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FLGH_OLEA2
Sequence: MRYAVICMLLLAASGCTAARQAPSPEPGLVPPPVVTTPEEKAENPGSLFSDENADLLYADYRARRVGDIVLINIVENSKAENKASTSTNKESTGEYGVSSFFDRSKVGIIPGQTLLSGRTGDVPLLKFSSVSDFSGDGETTRENTVTATIAARVTRVLPGGLMQVEGSRETRVNEETQIVTVSGLVRTSDVADDNSVMSTQMADARISYYGKGVISDKQRVGWFTRLMDNLWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: PSAJ_PROMP
Sequence: MLKIFNTKFIRSAPVVAAVWLSLTAGIIIEFNRFFPDLLFHPMS
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: YL8C_SCHPO
Sequence: MSAVDKTNNLPTLDTLQMVISDVDGTLLDKHHRFHFRTYRAMKYIREKYPNFPIVLATGKQRSAVDLIRIPLDLDAFPAAHVNGCVLYNKGKIVYADHLKPEVVMEVVEATKGNPNIANVVYDEHYVYALTPGREDMKNVKRLAEIGEKVDFSMPCEEAIEKVKSGEIKVIKMAVCEDPDKLDVVRDILGKFPREKFATTQALEFCIELIPSNSNKGTALQYITSNILPEVKNENVISFGDGQNDLSMFAIAGWSVAIKNGMPIAIEKAKAVSRVGNEEGAVGEVLERIFNIPEDYTPPPYTF
What are the official names of this protein?
Uncharacterized hydrolase C25B8.12c.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PPAC2_DROME
Sequence: MGKRSQKSSVLMVCVGNLCRSPIAEAVMRDLVARAGLQGEWHVESAGIEDWHSGHQPDERALNVLARHNIEYNGKARVLAPEDFLEFDYIFAMDLSNLAALRRMAPKGTTAKLLILGNFGLKPDERIIEDPYYDIGEASFEEIYRQCSIACRNFLKQARLKQIM
What is the function of this protein?
Catalyzes the dephosphorylation of tyrosine phosphorylated proteins and low-MW aryl phosphates (PubMed:10675607).  Can contribute to the regulation of a variety of developmental processes (PubMed:10675607).
What are the official names of this protein?
Low molecular weight phosphotyrosine protein phosphatase 2, Low molecular weight cytosolic acid phosphatase 2, PTPase 2.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP1_GLOVI
Sequence: MPIGIPKVPYRLPGGQSQWIDIFNRLALDRIIFLGREVDDEIANAIIASMLYLDSEDPEKDIFLYINSPGGSVSAGLAIYDTMQHVRADVATMCVGLAASMGSFLLTAGAKGKRTSLPHSRIMIHQPLGGAQGQATDIGIQAKEILYTKDRLNQILSERTGQPLERIERDTDRDFFMSAEDAKQYGLIDQVVQHRPV
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_METTP
Sequence: MTICVRVRVSGRVQGVGYRYYTTTHAKALGVKGWIRNLPGGGVEAVLEGERKSVGELLGLMKSGPSGAMVSGMEIAEVECKGHDDFKIIY
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RS21_ALCBS
Sequence: MPQVKVKEGEPFDVALRRFKRGCEKAGILSEVRRREQYEKPTQERKRKRAAAVKRHLKKLQREQLARKRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: LSRB_SHIF8
Sequence: MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTSGGNGAQQAGKELSVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPALKRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYSSPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAIIAPDANALPAAAQAAENLKNDKVAIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISVYVADALLKKGSMKTGDKLDIQGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKENIGKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: TM102_BOVIN
Sequence: MASAVWGNAPWWSPPPPAPARPLTDIDFCSGAQLQELTQLIQELGVQESWNDGPKPGPDLLQAKDFVFSLLSLIHRRDPRFPPQTELLLLRGGIREGSLDLGPAPLGPYTRGPHYDAGFTLLVPVFSLDGTGQELQLDMRSCYAWLCLPEQVRGTSVREAWQDCLGPPVPGGRDWIHPTDSREGPRDPQSSVDQPHSDIIEPEAHESLEKSPSNVSVPESPQQNLTDIGFPSLSEETNDDVTKAADVSPGPQPSEAREAWPTLCPAQVAAWFFASLAAVAESLFPVPGAPRLVHAARHAGFTTILLATPGPPRRLLLFDLIPVVSVAGWPQGARSHSWAGPLASESSSFYLVPGGGGQTERPGASGWQLCFARQELALKARIPTPLLQAHAAAQALLRPLVAGTRAAAPYLLRTLLYWACERLPALYLARPENAGACCLGLLDELGRVLEARTLPHYFLSGQKLRAGDGASSLLGALALLRGDPARALRAAVEEAKAARKGGGLAGVGAGSH
What is the function of this protein?
Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway.
What are the official names of this protein?
Transmembrane protein 102.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Also located in intracellular compartments.
Protein: NUON_HELAH
Sequence: MLIDSLHISFDSFNFESILPMLVLVCGGIFTLLINAFTSRFSRNLNMFLCMLFLVLDFLVVLGLEQQENAFFGFLSLDTLSLVSQSIVLISAFLLIFLALSKERFNEFQTAEFYPLYLFIIAGFQFMVSSNHLLLMLIGLETASLPICVLMALSGKRYGLEAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLYTEGVTNPMLFAMGVIFLIGAIGFKVSLVPFHTWMPDVYEGNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILITITIPNLIALWQEDVKRMLAYSSISHSGFALACVFIHTEESQKAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFDGLIKTHPLVAILGAIFVFGLAGIPPFSVFWGKFLAVESALESNHILLAAVMLANSAVAVFYYFRWLVAMFFNKPLQTQSYAESDIYTQNATMPIYAVIIAMALVCLFSVFMMRGLLEFVA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IDHH_YEAST
Sequence: MSKIKVVHPIVEMDGDEQTRVIWKLIKEKLILPYLDVDLKYYDLSIQERDRTNDQVTKDSSYATLKYGVAVKCATITPDEARMKEFNLKEMWKSPNGTIRNILGGTVFREPIIIPKIPRLVPHWEKPIIIGRHAFGDQYRATDIKIKKAGKLRLQFSSDDGKENIDLKVYEFPKSGGIAMAMFNTNDSIKGFAKASFELALKRKLPLFFTTKNTILKNYDNQFKQIFDNLFDKEYKEKFQALKITYEHRLIDDMVAQMLKSKGGFIIAMKNYDGDVQSDIVAQGFGSLGLMTSILITPDGKTFESEAAHGTVTRHFRKHQRGEETSTNSIASIFAWTRAIIQRGKLDNTDDVIKFGNLLEKATLDTVQVGGKMTKDLALMLGKTNRSSYVTTEEFIDEVAKRLQNMMLSSNEDKKGMCKL
What is the function of this protein?
May function in the production of NADPH for fatty acid and sterol synthesis.
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
Protein: SYY_XYLFT
Sequence: MSLVSNSIALIERGANEILKFDELERRLRSGRPLRIKAGFDPTSPDLHLGHTVLLNKMRQFQDLGHQVVFLIGDFTGMIGDPTGKNVTRKPLSREDVLANASTYEDQVFKVLDRTLTEVRFNSEWFEKMSAVDMIKLAAQHTVARMLERDDFAKRFASQQPIVIHEFLYPLIQGYDSIALRADVELGGTDQKFNLLMGRALQEHHGQPPQIVLTMPLLEGLDGVAKMSKSLGNYIGIKEPPIDIVTKTMKIGDDLMWRWIELLSFKISAAEAVALREAVAKSELNPREVKLRLAHELVSRFYDNAAAEKAIAGWQAVVTGQGNNNLLPLQKINVPADGVRLVALLTKSGLAPSNSEAMRKLKERAVRVDGIVVDDAHLHFVPGFEGLIQIGKRNFIKVRLVTSSESQEFPESNRIDKS
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBA_XENTR
Sequence: MRECISVHVGQAGVQMGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFTTFFSETGAGKHVPRAVFVDLEPTVIDEVRAGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDPVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVSEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIAAIKTKRTIQFVDWCPTGFKVGINYQPPTAVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGIDSYEDEDEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PSMD9_MOUSE
Sequence: MSGEDVPHRAESSEARAAAVSDIQDLMRRKEEIEAEIKANYDVLESQKGIGMNEPLVDCEGYPRADVDLYQVRTARHNIICLQNDHKALMKQVEEALHQLHARDKEKQARDMAEAREEAMNRRLASNSPVLPQAFARVNSISPGSPASIAGLQVDDEIVEFGSVNTQNFQSVQNVGTVVQHSEGKPLNVTVIRRGEKHQLRLIPTRWAGKGLLGCNIIPLQR
What is the function of this protein?
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the PA700/19S regulatory complex (RC).  During the base subcomplex assembly is part of an intermediate PSMD9:PSMC6:PSMC3 module, also known as modulator trimer complex; PSMD9 is released during the further base assembly process (By similarity).
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit p27 family.
Protein: SURE_LEPBP
Sequence: MNLLITNDDGISSAGIKALERVLGKSYNTYLIAPLKERSVTSMALTVFQGMRVERINDNHYIADGFPVDCVNIGLYAEIFPKIDFVISGINRGVNMGYDVHYSGTVGAAKHGALHGIPSLAVSSGRIDPEDGYEKEAELVLAFLEQYKSQIQSGEIWNLNFPPEVSGTGTISELVFTRLGRRRYSEKYEKKQIIEGVSEFQLNGSLLGHDEETGTDFEAYAQGKIPLTPIQLDLTEKNRLKELLTNR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTA3_RAT
Sequence: MPGKPVLHYFDGRGRMEPIRWLLAAAGVEFEEQFLKTRDDLARLRNDGSLMFQQVPMVEIDGMKLVQTRAILNYIATKYNLYGKDMKERALIDMYAEGVADLDEIVLHYPYIPPGEKEASLAKIKDKARNRYFPAFEKVLKSHGQDYLVGNRLSRADVYLVQVLYHVEELDPSALANFPLLKALRTRVSNLPTVKKFLQPGSQRKPLEDEKCVESAVKIFS
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  Catalyzes isomerization reactions that contribute to the biosynthesis of steroid hormones.  Efficiently catalyze obligatory double-bond isomerizations of delta(5)-androstene-3,17-dione and delta(5)-pregnene-3,20-dione, precursors to testosterone and progesterone, respectively (By similarity).  Has substantial activity toward aflatoxin B1-8,9-epoxide (By similarity).
What are the official names of this protein?
Glutathione S-transferase alpha-3, GST 2-2, GST A3-3, GST AA, Glutathione S-transferase Yc-1, GST Yc1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCMB1_HUMAN
Sequence: MVKKLVMAQKRGETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQEELKGKKVPQYPCLWVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADVEKVRAKFQEQQVFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMVKSNQYLSILAAQK
What is the function of this protein?
Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel.  Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.  Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel.  It also modifies KCNMA1 channel kinetics and alters its pharmacological properties.  It slows down the activation and the deactivation kinetics of the channel.  Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1.  Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2).  Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.
What are the official names of this protein?
Calcium-activated potassium channel subunit beta-1, BK channel subunit beta-1, BKbeta, BKbeta1, Hbeta1, Calcium-activated potassium channel, subfamily M subunit beta-1, Calcium-activated potassium channel subunit beta, Charybdotoxin receptor subunit beta-1, K(VCA)beta-1, Maxi K channel subunit beta-1, Slo-beta-1, Slo-beta.
What is the protein family that this protein belongs to?
Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB1 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TM40L_MOUSE
Sequence: MGNTLGLAPMGTLPRRSHRREEPLPNPGSFDELHRLCKDVFPAQMEGVKLVVNKVLSSHFQVAHTVHMSALGLPGYHLHTAYAGDWQLSPTEVFPTVVGDMDSSGSLNAQVLLLLAERLRAKAVFQTQQAKFLTWQFDGEYRGDDYTATLTLGNPDLIGESVIMVAHFLQSITHRLVLGGELVYHRRPGEEGAILTLAGKYSAVHWVATLNVGSGGAHASYYHKANEQVQVGVEFEANTRLQDTTFSFGYHLTLPQADMVFRGLVDSNWCVGAVLEKKMRPLPVTLALGAFLNHWRNRFHCGFSITVG
What is the function of this protein?
Potential channel-forming protein implicated in import of protein precursors into mitochondria.
What are the official names of this protein?
Mitochondrial import receptor subunit TOM40B, Protein TOMM40-like.
What is the protein family that this protein belongs to?
Belongs to the Tom40 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: RNP4_METMP
Sequence: MKLKKKFLEKSKKVAEERINILMNLAEKESNSGKTERSKNYVLLGKKIAMRMRMPYPKEWKRRICKNCGSFLIYGKNARVRTKAKNYPHVVITCLECNSITRIPIKTAKK
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRC3_NEOFI
Sequence: MKRKAEKQQATAPVSAFAARKARQQQAQLVEPEKTAQNEPAVEPPSKRARWSPEEGAARQAANGNDRVQTRRSTRRKAETLSSELAEKQPQRSAAAARAQIAERTPAPEKGDAETSDAAEEEEEDILERENGVGVIAAEDDAEGYESPADDVPQVQNFPLSKTRLNKSNIVFSDERTLCVRIKEKMTLVLLGHYDLWVKRGVISLMGAKLHPSPRLYRVYAPSTHSLPVIKCVAGVDGEAEIEVKSCNSGIYRLRHLSPLYQRIWNGKNTAADKLTLKKASASTKRTFSVLYTSSDDSWNRHLRPLHLEKQWSSAIRSLSQRGGRLKVLICGPKASGKSTFSRYLLNHLLSPAPQTENNHRNTDGVAFLDLDPGQPEFSPMGQVYLAHLRSPFFGPPFTHPSLAESQDGSIIRSHHIGVTSPKEDPDHYVLAAMDLMDRYRALLASYPQCPLIINYPGWIFGLGLEVATWLVKSLGLSDVVYMSEKGPAEVVEPLGHAAQEARVPLTTLPSQPTDFVSRSSAQLRSMQVQSYFHMSHPSEIHNPQWLDTTMSRSRPLVVDYAGPRQGIRGIMVMGSQISPDLLHEALDGALVGVVAVESPNAIMGQADTAGFSGSSQRDATQGAEDLSGAASDVDMNDVTDASHGDVAPTSSSSVESMITRTPNEDLPYLFVGSGSCNPLDPKASNCLGLALVRSIDVPSRKLELITPIPGSKLRDALEQGHGIVLVRGMLDNPSWAISEDYYAARAAEKHHQELVAKARKETDTRDGRDAAGDADTQGMVSALLRDRIRRASNVPWMTVIEDNSRRHREAAQREKSLWKLRKKAYPGSESETDW
What is the function of this protein?
Polynucleotide 5'-kinase involved in rRNA processing.
What are the official names of this protein?
Polynucleotide 5'-hydroxyl-kinase grc3.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. NOL9/GRC3 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: YIDC_VIBVY
Sequence: MDSQRTLLVLLLALVSFLLFQQWQVAKNPAPQAVEQAQTSSTLPAPSFADELDPAPAQQASAKLITVTTDVLTLSIDTVGGDVVAADLNQYSAELNSANAFELLRDTQGHQFIAQSGLVGPQGIDLSSNNRPSYQVSADSFTLADDQNELRIPMTYQANGLEYTKTFILKRGSYAIDVEFDVINKSGNNATLGMYAHLRQNLMDAGGSITMPTYRGGAYSTEDTRYKKYSFEDMQDRNLSLTLTNGQGWAAMIQHYFAAAWIPRNEPGANLYTRVIGNMGDIGVRMPNKTVADGDSAHFTATLWAGPKLQDQMAEVAPNLDLVVDYGWLWFIAKPLHWLLSVIQSFVGNWGVAIICLTFIVRGAMYPLTKAQYTSMAKMRMLQPKLQAMRERIGDDRQRMSQEMMELYKKEKVNPLGGCLPLILQMPIFIALYWALMESVELRHSPFILWIHDLSAQDPYFILPLLMGGSMFLIQKMSPTTVTDPMQQKIMTFMPVMFTFFFLWFPSGLVLYWLVSNIVTLIQQSLIYKALEKKGLHTK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.