PharMolix/UniProtQA huggingface dataset:
Protein: GATB_BRADU
Sequence: MSTATHKLLKGATGDWEMVIGMEIHAQVTSNSKLFSGASTAFGGEPNSHVSLVDVAMPGMLPVINEECVRQAVRTGLGLNAKINLRSVFDRKNYFYPDLPQGYQISQYKSPVVGEGEVLVELDGGRSVTVGIERLHIEQDPGKMLHDQSPSLSLIDFNRCGVALMEIVSKPDIRDAEQAKAYVTKLRSIMRYLGTCDGDMEKGNLRADVNVSVRKPGGPLGTRCEIKNMNSINFIGQAIEYEARRQIEILEDGGQIEQETRRFDPDKGETRSMRSKEEAHDYRYFPDPDLLPLEFSQEFVDELKAKLPELPDQKKTRFVADFGLSAYDASVLVAERESAVFYETVLDKLGDRARDGKMAANWVINELFGRLNKEGRDITGSPVTAEQLAAIIDLIGEGTISGKIAKDLFEIVWQEGGDPRALVESRGMKQVTDLSAIEKVVDDIIAANPDKAAQVKDKPQSLGWFVGQVMKASGGKANPQSVNELLKSKLGI
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: METK_MYCBO
Sequence: MSEKGRLFTSESVTEGHPDKICDAISDSVLDALLAADPRSRVAVETLVTTGQVHVVGEVATSAKEAFADITNTVRARILEIGYDSSDKGFDGATCGVNIGIGAQSPDIAQGVDTAHEARVEGAADPLDSQGAGDQGLMFGYAINATPELMPLPIALAHRLSRRLTEVRKNGVLPYLRPDGKTQVTIAYEDNVPVRLDTVVISTQHAADIDLEKTLDPDIREKVLNTVLDDLAHETLDASTVRVLVNPTGKFVLGGPMGDAGLTGRKIIVDTYGGWARHGGGAFSGKDPSKVDRSAAYAMRWVAKNVVAAGLAERVEVQVAYAIGKAAPVGLFVETFGTETEDPVKIEKAIGEVFDLRPGAIIRDLNLLRPIYAPTAAYGHFGRTDVELPWEQLDKVDDLKRAI
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EAF6_XENTR
Sequence: MAMHNKATPPQIPDTRRELAELVKRKQELAETLANLERQIYAFEGSYLEDTQMYGNIIRGWDRYLTNQKNSNSKNDRRNRKFKEAERLFSKSSVTSAAAVSALAGVQDQLIEKREPGSGTESDNSPDFQNQENEPSQDDTEDLDGSLSGVKPQKAASSANSGGHHSSHKKRKNKNRHRIDLKLNKKPRSDY
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A.  This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription.  Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4.  Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (By similarity).
What are the official names of this protein?
Chromatin modification-related protein MEAF6, MYST/Esa1-associated factor 6, Esa1-associated factor 6 homolog, Protein EAF6 homolog.
What is the protein family that this protein belongs to?
Belongs to the EAF6 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome, centromere, kinetochore.
Protein: PDXH_RHOJR
Sequence: MNKDLAAMRVGYAHQGADGRYVDSDLDADQLIGGWLPLMRLWLEDAVEAGVPEPNAMTLGTVDEHGHPCTRTVLCKGLSTDGVLFFTNYDSDKGRQLEAVPYASVTFTWVPVARQITVRGPVERVSAEVTDEYWHSRPRGSRLGAWASEQSKPIGSRAELDAALLHAAERFPVDVDIPVRPDWGGILIRPAVVEFWQGRANRMHNRIRTSLVDGSWTVERLQP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: ATPD_SERP5
Sequence: MSEFVTVARPYAKAAFDFAVEHQSLDRWQDMLAFAADVTRNEQISELLAGAVAPETLSRTFIAVCGEQLDEHGQNFIRVMAENGRLLVLPAVLQQFIELRALLESTVEVEVLSASALNDKQLANIAAAMEKRLSRKVKLNCKIDKSVLAGVIIRAGDMVIDGSVRGRLERLTDVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VIRD2_RHIRD
Sequence: MPDRAQVIIRIVPGGGTKTLQQIINQLEYLSRKGKLELQRSARHLDIPVPPDQIRELAQSWVTEAGIYDESQSDDDRQQDLTTHIIVSFPAGTDQTAAYEASREWAAEMFGSGYGGGRYNYLTAYHVDRDHPHLHVVVNRRELLGHGWLKISRRHPQLNYDGLRKKMAEISLRHGIVLDATSRAERGIAERPITYAEHRRLERMQAQKIQFEDTDFDETSPEEDRRDLSQSFDPFRSDPSTGEPDRATRHDKQPLEQHARFQESAGSSIKADARIRVSLESERSAQPSASKIPVIGHFGIETSYVAEASVRKRSGIFGTSRPVTDVAMHTVKRQQRSKRRNDEEAGPSGANRKGLKAAQVDSEANVGEQDTRDDSNKAADPVSASIGTEQPEASPKRPRDRHDGELGGRKRARGNRRDDGRGGT
What is the function of this protein?
Tumor formation by A. tumefaciens involves the transfer and integration of a defined segment (T-DNA) of Ti plasmid DNA into the plant nuclear genome.  The virD operon encodes a site-specific endonuclease that cleaves at a unique site within both 24 bp direct repeats flanking the T-DNA.
What are the official names of this protein?
T-DNA border endonuclease VirD2.
Protein: DEOD1_ALIF1
Sequence: MATPHINAEMGDFADVVLMPGDPIRAKYIAETFLDDVVQVCDVRNMYGFTGTYKGRKISVMGHGMGIPSCSIYMTELIKDFGVKKVIRVGSCGAVNEGIKVRDVVIGMGACTDSKVNRIRFKDHDFAAIADYEMVRNAELAAQARGIDVKVGNLFSAELFYTPDPSMFDLMDKYGIVGVEMEAAGMYGVAAEYGAKALAICTVSDHIKTGEQTTSDERATTFDEMMLIALDSVLLGDK
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type 1, PNP 1.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: ARNE_ECOUT
Sequence: MIWLTLVFASLLSVAGQLCQKQATCFAAVNKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSLRHWCGVAFIIGGIVILGSTV
What is the function of this protein?
Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane.
What are the official names of this protein?
Probable 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE, L-Ara4N-phosphoundecaprenol flippase subunit ArnE, Undecaprenyl phosphate-aminoarabinose flippase subunit ArnE.
What is the protein family that this protein belongs to?
Belongs to the ArnE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFG_HALOH
Sequence: MARQYPLKKTRNIGIMAHIDAGKTTTTERILYYTGRVHKMGEVHDGAAVMDWMEQEQERGITITSAATTCEWQKHRINIIDTPGHVDFTVEVERSLRVLDGAIALFCAVGGVEPQSETVWRQADKYQVPRIAFVNKMDRMGADFFHVIEMMEDRLGANAVPLQIPIGSEDDFEGIVDLVTMDAVVYKDDLGVKYERVDIPEDYREQAEEYRENLLEAISELDDEIMMKYLEGEEITTDELKTALRKGVLDVEIVPVLCGSAFKNKGVQLLLDAVIDYLPSPVDVPPVEGMNPDTEEEEIRKAGDDEPFSALAFKIMADPYVGKLTFFRVYSGVLEAGSYVYNSTKGHKERIGRILQMHANHREERESVHAGDLAAAVGLKNTATGDTLCDEDHPIVLESMEFPEPVISVAIEPKSQAEQDKLSLALQRLAEEDPTFKVRTDEETGQTIIRGMGELHLEVIVDRLLREFKVDANIGRPQVAYRETITRKVTDVEGKFIRQSGGRGQYGHVIIDIEPLEEGEGFEFVNKIVGGAIPKEYIPAVEDGIVEAMENGVLAGYPAVDLKITLKDGSYHEVDSSEMAFKIAGSIAFKEGAQKASPVILEPIMDVEVVVPEEYMGDVIGDLNGRRGNVQGMERRASAQVVKAYVPLAEMFGYATDLRSKTQGRATYTMQFSHYEPVPDNIAKEIIGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSX_BACSU
Sequence: MIKILGRHLRESFKSLGRNTWMTFASISAVTVTLILVGVFLVIMLNLNNMATNAEKQVEIKVLIDLTADQKAQDKLQNDIKELKGIQSVTFSSKEKELDQLVDSFGDSGKSLTMKDQENPLNDAFVVKTTDPHDTPNVAKKIEKMDHVYKVTYGKEEVSRLFKVVGVSRNIGIALIIGLVFTAMFLISNTIKITIFARRKEIEIMKLVGATNWFIRWPFFLEGLLLGVFGSVIPIALVLSTYQYVIGWVVPKVQGSFVSLLPYNPFVFQVSLVLIAIGAVIGVWGSLTSIRKFLRV
What is the function of this protein?
Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation.  May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation.  Acts upstream of the histidine kinases KinA, KinB and KinC, the RapA phosphatase and the Spo0A sporulation protein.
What are the official names of this protein?
Cell division protein FtsX.
What is the protein family that this protein belongs to?
Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on FtsZ. Present in detergent-resistant membrane (DRM) fractions that may be equivalent to eukaryotic membrane rafts; these rafts include proteins involved in signaling, molecule trafficking and protein secretion (PubMed:23651456).
Protein: RBFA_RHOPB
Sequence: MPKHHQKAQSPGGSQRQLRVGEIVRHAVAELLSQGGVHDPVLEGHLITVPEVRMSPDLKLATVYVMPLGGRDTDVVLKALAANKPFIRTAVARRVNLKFAPDLRFRIDERFDEAERIEKLLRTPGVQKDLQQDSDET
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KANK2_BOVIN
Sequence: MAQVLHVSAPFPGTPGPASPPAFPSKEPDVPYSVETPYGYRLDLDFLKYVDDIEKGHTLRRVAVQRRPRLGSLPRGPGSWWTSTESLCSNASGDSRHSAYSYCGRGFYPQYGALETRGGFNPRVERTLLDARRRLEDQAAAPAGLGSLTPSAAGSTSSLVGVGLPPPTPRGSGLSTPVPPSAGHLAHVREQMAGALRKLRQLEEQVKLIPVLQVKLSVLQEEKRQLTVQLKSQKFLGHPAGARGRGELCLDLPEAPEDPVTLETRSVGTWVRERDLGMPDGEAALAAKVAVLETQLKKALQELQAAQARQADLPPQAWPPPDSPVRVDTVRVVQGPREVEVAASTAAGAPAQRAQSLEPYGAGLRALATSNGAESPPVFRSHEVMETVFPAPTASTSNVHQVKKISITERSCDGAAGHPQAPAESSLSPPESEGATQAQPEKNTGQVPAHDDTTIKEPIRQAACHESEFEEAGGAGGAQAGLRSIMKQKEEPTDPEAHRRSLQFVGVNGSISPRYESSSEDSSTAENFSDNESTENEAPEPEERVPSVAEAPQLRPKETAKAKTSREESQLPQESLHTPTAEGASGSSAKDEIRMELSPDLISACLALEKYLENPKALTERELKVAYTTVLQEWLRLACRSDAHPELVRRHLVTFRAMSARLLDYVVNIADSNGNTALHYSVSHANFPVVQQLLDSGVCQVDKQNRAGYSPIMLTALATLKTQDDIQTILQLFRLGDVNAKASQAGQTALMLAVSHGRVDVVKALLACEADVNVQDDDGSTALMCACEHGHKEITALLLAVPSCDISITDRDGSTALMVALDAGHSEIASMLYSRMNIKCSFAPMSDDESPASSSAEE
What is the function of this protein?
Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (By similarity).  Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (By similarity).  Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (By similarity).  Involved in the negative control of vitamin D receptor signaling pathway (By similarity).  Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (By similarity).  May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (By similarity).  Through the Rho signaling pathway may also regulate cell proliferation (By similarity).
What are the official names of this protein?
KN motif and ankyrin repeat domain-containing protein 2, Ankyrin repeat domain-containing protein 25.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion.
Protein: LYZL5_HUMAN
Sequence: MKAWGTVVVTLATLMVVTVDAKIYERCELAARLERAGLNGYKGYGVGDWLCMAHYESGFDTAFVDHNPDGSSEYGIFQLNSAWWCDNGITPTKNLCHMDCHDLLNRHILDDIRCAKQIVSSQNGLSAWTSWRLHCSGHDLSEWLKGCDMHVKIDPKIHP
What are the official names of this protein?
Sperm acrosome-associated protein 5, Lysozyme-like protein 5, Sperm-specific lysozyme-like protein X, SLLP-X.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDUB4_CHICK
Sequence: MASGPSRTAAEEYRPNRYVSLPAELDPATYDTPLEKRRAEAERLAIRARLKRQYLLQLNTPKPPRVIEDPALLRWDYARTHNVYPTFRPTPKTSFLGAVFAIGPILFWIAAFKTERVSSAGGVEHQGAPGCKT
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4, Complex I-B15, CI-B15, GGHPW, NADH-ubiquinone oxidoreductase B15 subunit, Protein Walter.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB4 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: 3SA2_NAJMO
Sequence: LKCNQLIPPFWKTCPKGKNLCYKMTMRGASKVPVKRGCIDVCPKSSLLIKYMCCNTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 2, CTX M2, Cardiotoxin IIA, CTX IIA, Cytotoxin V(II)2.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: UP02_GINBI
Sequence: LFSLCXXXLKR
What are the official names of this protein?
Unknown protein 2.
Protein: SMG_SHEPC
Sequence: MFDILMYLFENYVHSEVELLVDEDELTKELTRAGFHQSEILKALTWLERLAELQEGDKPYLCNHDQHSFRIYTKDEMDKLDVESRGFLLFLEQVKVLNVETREMVIDRVMELDEPTLILEDLKWVILMVLFNAPGHESAYEQMEDLIFEQPEGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: HLDD_PECCP
Sequence: MIIVTGGAGFIGSNIVKSLNDIGYRDILVVDNLKDGTKFVNLVDLDIADYMDKEDFIASIVAGDDLGDIDAVFHEGACSSTTEWDGKYMMDNNYQYSKDVLHYCLDRNIPFLYASSAATYGGRNDNFIEERQYEQPLNVYGYSKFLFDQYVREILPEAESQICGFRYFNVYGPREGHKGSMASVAFHLNNQINQGENPKLFSGSENFKRDFVYVGDVAAVNLWFWQNGVSGIFNCGTGRAESFQAVADATLAFHKKGGVEYIEFPEKLKGRYQAYTQADLTNLRAAGYDKPFKTVAEGVAEYMAWLNRTV
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: RS18_CYTH3
Sequence: MTLQNESINRVENRKKYCRFKKMGIFYIDYKDPNFLLKFVNEQGKILPRRLTGTSLKYQRKVSQAVKRARLIGLLPYVTDSLK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: KHSE_NITWN
Sequence: MAVYTDVAAEELADFLKAYDIGELLSYKGIAEGVENSNYLLHTTSGSFFLTLYEKRVAIDDLPFFLGLMGHLATHGIVCPQPVRTRNGETLGSLAGRPAAIIDFLEGVWPRKPNVAHCAAVGAALAKLHLAGRDFSMRRANALSVWSWRPLFEQAGACADTVQPGLHDFLKAELDHLEARWPQELPGGVIHADLFPDNVLFLGDRLSGLIDFYFACHDFFAYDVAICLNAWCFEPDHAFNVTKARALLGAYHRERALSEAEQAALPLLARGAALRFLLTRLVDFLNVPAGALVKPKDPLEYVRKLRFQQRVGGVRDYGVAILGPVA
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: Y2595_YERPS
Sequence: MTIKPSDSVSWFQVLQRGQHYMKTWPADKRLAPVFPENRVTVVTRFGIRFMPPLAIFTLTWQIALGGQLGPAIATALFACGLPLQGLWWLGKRAITPLPPTLLQWFHEVRHKLSEAGQAVAPIEPIPTYQSLADLLKRAFKQLDKTFLDDL
What are the official names of this protein?
UPF0208 membrane protein YPTB2595.
What is the protein family that this protein belongs to?
Belongs to the UPF0208 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_FRAP2
Sequence: MNLDFIKDRIVAVPDFPKPGIVFRDITPLLADPQGLKMTAKAMAEELKSKGIKPTVIAGTESRGFIFGVALAEVLGLGFVPVRKPGKLPRETYKVSYQLEYGSDSLEIHKDAFKPTDKVLVVDDLLATGGTAKATVQLIEKTQASVAGLIFVIELEDLNGRKVLEGHNVSALVKY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RINT1_MOUSE
Sequence: MLAADDIGEVPAAPCCPESGDETKNTDVKSDVNTAAPAGSEQLSQGGSDDALLSYVSAFIEKEVGSDLKSLKTLGKLIEQMTESKVKLEEQVLTISSEIPKRIQSALKDAEESKQLLDEFLEQEAPLFSSISSHLLMAQPWMDDLGAMITQMEEIERHLAYLKWVSQTEELSDNIQQYLMTNSVPEAASLLVTMTELDIQLQESSCTHLLSFMRATVKFWHKILKDKLTSDFEEVLAQLHWPFTSHTQSQTVGGSRPAGTPELYSSLDTLFCQLLKLQASDELLTEPKQLPEKYCLPASPPVTLPIQVMLAPLQKRFRYHFRGSRQTNVMSKPEWYLAQVLMWIGNHTQFLDEKIQPILDKVGSAVNARLEFSRGLVMLILEKLASDIPCLLYDDSLFCHLVDEVLLFERELHTVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAAWVSQYKDISDVDEMKVPDCAEVFMTLLLVITDRYKNLPTASRKLQFLELQKDLVDDFRIRLTQVMKEETRAALGFRYCAILNAVNYISAVLADWADNVFFLQLQQAALEVFAENNVLSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDSAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFRIFWQMLAEKLDLYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIILNLNIGSALLLKDVLQSVSEHIPATAALNEVGVYKLAQQDVEILLNLRTNWPNTGK
What is the function of this protein?
Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER.  May play a role in cell cycle checkpoint control.  Essential for telomere length control (By similarity).
What are the official names of this protein?
RAD50-interacting protein 1, RAD50 interactor 1, RINT-1.
What is the protein family that this protein belongs to?
Belongs to the RINT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: APT_SHEFN
Sequence: MMNQDSLALIKQSIKTIPDYPIPGIMFRDVTSLLENAEAYKATIAILVAHYQSKGFTKVVGTEARGFLFGAPLALELGVGFVPVRKPGKLPRKTISQTYDLEYGKDTLEIHVDAINANDKVLVIDDLLATGGTIEATVKLIRELGGEVSHAAFVISLPEIGGEKRLQGMGIEVLSLCEFDGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPP_STAA8
Sequence: MKRNFPKLIALSLIFSLSVTPIANAESNSNIKAKDKKHVQVNVEDKSVPTDVRNLAQKDYLSYVTSLDKIYNKEKASYTLGEPFKIYKFNKKSDGNYYFPVLNTEGNIDYIVTISPKITKYSSSSSKYTINVSPFLSKVLNQYKDQQITILTNSKGYYVVTQNHKAKLVLKTPRLEDKKLKKTESIPTGNNVTQLKQKASVTMPTSQFKSNNYTYNEQYINKLENFKIRETQGNNGWCAGYTMSELLNATYNTNKYHAEAVMRFLHPNLQGQRFQFTGLTPREMIYFGQTQGRSPQLLNRMTTYNEVDNLTKNNKGIAVLGSRVESRNGMHAGHAMAVVGNAKLDNGQEVIIIWNPWDNGFMTQDAKNNVIPVSNGDHYRWYSSIYGY
What is the function of this protein?
Cysteine protease that plays an important role in the inhibition of host innate immune response.  Cleaves host elastins found in connective tissues, pulmonary surfactant protein A in the lungs, and the chemokine receptor CXCR2 on leukocytes.  Proteolytic cleavage of surfactant protein A impairs bacterial phagocytosis by neutrophils while CXCR2 degradation blocks neutrophil activation and chemotaxis.  Additionally, promotes vascular leakage by activating the plasma kallikerin/kinin system, resulting in hypotension.
What are the official names of this protein?
Staphopain A, Staphylococcal cysteine proteinase A, Staphylopain A.
What is the protein family that this protein belongs to?
Belongs to the peptidase C47 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSK_RICPR
Sequence: MLFYINKILSNNKVQAVILWIIGLAIVIVLMSYNIDDPSFNSVTTEYPSNLIGIVGAYLSDFLYQFFGLTSFIIPLACFIWGRNCWYGRYRSAFIRIFVVLLALISSSTLLSKIKLELIPASAGGAIGIIVSNFCERFINQLYLLLIFPTFIILVVLLEIKFTAISNFMIKLSKFLTYWILLFFNYVLPRLSLIGLFPIKNNDKLNITSFYQKPASGKVKFTEEASLIPANPIKCFIKPVCTKISQNQIASLPPISLLCDPKNNHVKGASSSELKQKAEELLTVLNDFGVKGQIININQGPVVTQYEFEPAAGTKTSRVVGLSDDIARSLSALSTRIAVIPGKNVLGIELPNKQREFFCLKELIETNEYQDKSILLPLVLGKDLAGKPLIADLAKMPHLLVAGTTGSGKSVGINAMIVSLLYRYTPEECRFIMIDPKMLELSAYDGIPHLLTPVVTEPSKAVIALKWAVKEMENRYRMMSNIGVKNIAGYNAKILEAVKENRVIERPIQTGFDPETGKPIYETVTMNMVKLPYIVVIVDEMADLMLVSGKDIEMLIQRLAQMARAAGIHIIMATQRPSVDVITGVIKANFPSRISFKVTSKIDSRTILGEQGSEQLLGMGDMLFMGNTSKISRVHGPFVNEAEIAKITEYLKETSMPVYISAVTEQPEENYSSIDIGDGSIDEVLYKKAVQIVRNERKSSISYIQRSLRIGYNKAANLVEKMEKDGIVSSPNHTGKREILLPEM
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination.  FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation.  FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Located at the septum.