PharMolix/UniProtQA huggingface dataset:
Protein: BESB_STREN
Sequence: MSAGSPAEPRPVPGSVHSVSVSIPDVRSVIGFESGDPATLRRIAWGYPRFRTHPYVARVAALVAGAVGGRAQDLVLTRSVRAAEAAAAYAGLAPGAVFEASGVRGVRVAEDDPALAAVRGHVQHTGAHLTSREAEDVLLEAGLIEARQAEEAVSEEPAEAVRSALATAYGAGDPADVSLHNSGMNAVAAAVAAVTDLQRPAGRRRWIQLGWIFFDTMSLLDKRLFGTDHVTVPDPFDLAALSRVVAAHPGQLAGIIAELPSNPSLRCPDVPALREIADRAGCALVLDATIATPHNVDVLGYADVVCESLTKYATGSADVLMGAAVVGSASPWAAQLREGLRRFGDVPYHRDAARVAARIRDYGDRMKRVNAGAVALAGFLERQSAVRAVSWPYDAASQANYRKVERLSDAPGGLLMVDLRVPLERVYDRLAVAKGPSFGAEFTMASPQIFIAHFDLLSTPEGRAELRSRGLHRDMLRISVGVEDPELIAEVFRDAFDGAG
What is the function of this protein?
Involved in the biosynthesis of terminal alkyne-containing amino acids such as L-propargylglycine (Pra) and L-beta-ethynylserine, that are produced as antibiotics by S. cattleya.  Catalyzes gamma-elimination of chloride from 4-chloro-allyl-L-glycine (also named L-2-amino-4-chloropent-4-enoate), followed by an isomerization, to form the terminal-alkyne product L-propargylglycine.
What are the official names of this protein?
L-2-amino-4-chloropent-4-enoate dechlorinase/desaturase, 4-chloro-allyl-L-glycine acetylenase, L-propargylglycine synthase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: PRR15_HUMAN
Sequence: MADSGDAGSSGPWWKSLTNSRKKSKEAAVGVPPPAQPAPGEPTPPAPPSPDWTSSSRENQHPNLLGGAGEPPKPDKLYGDKSGSSRRNLKISRSGRFKEKRKVRATLLPEAGRSPEEAGFPGDPHEDKQ
What is the function of this protein?
May have a role in proliferation and/or differentiation.
What are the official names of this protein?
Proline-rich protein 15.
What is the protein family that this protein belongs to?
Belongs to the PRR15 family.
Protein: TATA_NEIG1
Sequence: MGSFSLTHWIIVLIIVVLIFGTKKLRNVGKDLGGAVHDFKQGLNEGTDGKEAQKDDVIEHKKDEDKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HEM1_BORPA
Sequence: MSVAVLAFGLNHTSAPVSVRERVSMPVDLVKPALEGLRATFGGAVREAAILSTCNRTELYCAAEGQVAEHLPAWLAEHNRLEAAALRPHLYRHQHDDAVRHAFRVASGLDSMVLGEPQILGQMKDAVRAANEAGALGTLLHQLFQRTFSVAKEVRSQTAIGAHSVSMAAAAVRLAERVFGQLEDARTLFIGAGEMIELCATHFAAQRPRSMVVANRTIERAETLAGRFSAQTMKLADLTERLAEFDVIVSCTASSLPILGLGMVERATRQRRHRPMVMIDLAVPRDIEPEVGRLDDVYLYSVDDLGRLVQSGTDARRAAVVQAEAIIETRVQGFMHWMQSREVVPVIRDLHQAADDVRAAELERARRMLARGESPEAVLEQLAHGLTQKYLHGPLAALNRSEGDERRQLLAWVPRLFPGRDSRR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DAPA_SPHAL
Sequence: MFSGSIPALVTPFRDGAFDAPTFARLVDWQVKEGTSALVPCGTTGESPTLSFDEHYRVIDCCIEAAAGRVPVIAGCGSNDTATAIRHMRHAQASGADAALIVAPYYNRPSQEGMIAHFKALADASDLPIVVYNVPGRTVADISAETMCKLAEIPTVVAVKDASGDLARVTVHRKGARHGFCQLSGNDELWLPHAVMGGAGCISVTANVAPRLCADFAAACAAGEWTRALALHDRLFDLHKAMFSDTSPGPVKYALSRVHDWFSPEVRLPIIPASGASRAVVDAALASAGVI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTB_PANTR
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.  Part of the ACTR1A/ACTB filament around which the dynactin complex is built.  The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity).
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Protein: Y1786_VIBCH
Sequence: MTHFPRHRYLLSQRAYEHRVLEEAAEILEQRYVRGETFARTENTTEYLRCKLAGYEHEIFAVLFLDNQHRLIEFKELFRGTVDAASVYPREVLKEALNVNAAAVIFAHNHPSGDPEPSQADRRITQRLKDALSLVDIRVLDHVVVGKSSVSFAERGWL
What are the official names of this protein?
UPF0758 protein VC_1786.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: 3SA3_NAJHA
Sequence: LKCYKLVPPFWKTCPEGKNLCYKMYMVSTLTVPVKRGCIDVCPKNSALVKYVCCNTDKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 3, Toxin CM-8/CM-8A.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: YI81_SCHPO
Sequence: MLLLLYICCLFLKFILANVDLTFVEYAKLPSKYAELLANATNQQGVMLFSTGDIRIGAYNYLVNNVTEINNDTDAYLCQLLTGQYTTDCYIFDTNSDDKPETFNSSIHLLNSDLDPK
What are the official names of this protein?
UPF0321 protein PJ695.01c.
What is the protein family that this protein belongs to?
Belongs to the UPF0321 family.
Protein: GLND_VIBA3
Sequence: MPYQCPITFNDEQLEICELKNQLEIFTQYQKSEFLNHHPVTDLVLLRSEYMDLLLNRLWEHFGFSKLPHIALVAVGGYGRGELHPLSDIDILIVSQRTLPSALGEKVSQFITLLWDLKLEVGHAVRTIAECIEIGSDDLTVATNLQESRLLCGSEDTFQELKLKIHSDSFWPSETFYKAKIQEQRERHARYHDTTYNLEPDIKSTPGGLRDIHTLSWVARRHFGATSLLEMSKYGFLTDAEYRELVECQDFLWRVRFALHIELRRYDNRLTFAHQAQVAEHLGYTGEGNRGVEMMMKEFYRTLRRVAELNKMLLKLFDQAIINGGQTQEAEILDNDFQRRGSLIEARKPALFQARPETILDMFIHIANDSTIEGVSPPTLRQLRTARRRLNRFLHTIPEARDKFMDLVRHPNALHKAFSLMHKLGVLSAYLPQWSQIVGQMQFDLFHVYTVDEHSIRLLKHINRFSQVENHDKHPICCEVYPRVQKKELLILAAIFHDIGKGRGGDHSEIGAVEAYSFCIEHGLSKPEAKQVAWLVQNHLLMSVTAQRRDIYDPDVITEFAKKVRDEESLELLVCLTVADICATNPELWNSWKRTLLAELFHSTQRALRRGLENPVDVRDRIRHNQQMASALLRKEGFSAREIEVLWQRFKADYFLRHTHTQIAWHCEHLLRLEDPSQPLVLISKKATRGGTEVFVYCKDQAALFATVVAELDRRNFNVHDAQVMVSKDGHVLDTFIVLDQHGEAIDEARHKAVAKHLTHVLADGRPTKIKTRRTPRNLQHFKVKTRVEFLPTKSKKRTLMELRALDTPGLLAQVGATFAELDINLHGAKITTIGERAEDLFILTSDAGGRLSEEQEQALRERLTEHVSELAP
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: ACP_SPHAL
Sequence: MSDSAEKVKKIVVEHLGVEADKVTEEASFIDDLGADSLDIVELVMAFEEEFGVEIPDDAAEKIATVKDAIDYIEANKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_THISH
Sequence: MSTQHSGDKLWGGRFSEPTDAFVEAFTASVSFDQRLYRHDIQGSKAHARMLARVGVLTEEECDKIHDGLDAILADIERGDFAWSVELEDVHMNVEARLIERIGDVGKKLHTGRSRNDQVATDIRLYLREAIDALMQEIRRLQGGLVDLAEREAQTIMPGFTHLQTAQPVTFGHHMMAWYEMLERDHGRLADCRKRVNVLPLGAAALAGTPYPLDRHYTAELLGFDAVTDNSLDAVSDRDFAIEFCAAGALIMTHLSRFSEELILWASAQFGFVDLPDRFCTGSSIMPQKKNPDVPELVRGKTGRANGNLIALLTLMKGQPLAYNKDNQEDKEPLFDTVDTLAGSLRAFADMVPHIQVRAEVMRAAASRGFATATDLADYLVRRGMPFRDAHEVVGRAVRHGVETGKDLAEMSLDELRKFSKTIEQDVFEVLTLEGSVAARNVHGGTAPAQVRARIRAARAKLMPAKG
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URED_ENT38
Sequence: MQGTPAKKHTHGWQASLALQFCHTPEKTVLHSARHVGPLTVQRPFYPEEETCHLYLLHPPGGIVGGDELNISVQLDPNSHALITMPGAGKFYRSSGPLARLNQHFFLEENATLEWLPQDTIFFPGANAVLQSVFHLHHSSRLLAWELFCLGRPVINETFSHGTIESRLEVWLDDEPLLIERQHLADGDLTTVANHPWIGTLLCYPASDALLEGVREKLVTLDNFAGATLTDGLLSIRFLSHDNLICQRAMREIWQCLRPHVIAKTPHPPRIWQT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDEP_BACSU
Sequence: MRNRKLGIDYSSDDFEGCPVETTLDIIGGKWKGILLYHLIDGKKRFNEFRKLYPKITQRMLTLQLRELERDGVIHREVYKQVPPKVEYSLTEFGRTLEPVILHMKDWGEKYKDRIDKLEAARKAEDKI
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YdeP.
Protein: BIOD_PSEA8
Sequence: MPAFFVTGTDTEIGKTTIAAGLLHAARSAGLSTAAAKPVASGCEPTAQGLRNGDALVLLGQCSLALAYEQVNPLAFAPAIAPHLAAREAGVELSAARLHEAVREVLALQADFTLVEGAGGWRVPLLGRENLSDLARLLALPVVLVVGVRLGCINHALLSAEAILGDGLALVGWVANVVDPATSRLEENLATLAERLPAPCLGRVPRLEEATPAAVAAHLDLRPLGIGL
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_CHLMU
Sequence: MAVPRNRHSNARKNIRRSHHAKKACSGAVCNNCKQVFIPHTVCASCGFYKGKAVVTVEK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ACKA_BACHK
Sequence: MSKIIAINAGSSSLKFQLFEMPSETVLTKGLVERIGLEDSIFTITVDGEKQKEITNIPDHAVAVNMLLKKLTENGIVKSLDEIGGIGHRVVHGGEKFADSVLITDEVLADIEELSDLAPLHNPANVVGIKAFQEVLPNVPAVAVFDTAFHQTMPESAFLYSLPYEYYEKFGIRKYGFHGTSHKYVTERAAELLGRPLESLSLLSCHLGNGASIAAVEGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPYIMEKTGQTVEEVVSVLNKKSGMLGLTGYSSDLRDIIAKEEEGDHRAKVALDVFVSRIHKYIGSYTARMKGVDAIIFTAGVGENSAIIRERVLEGLEYMGVYFDAKRNNVFGEEAFINFPHSPVKIIVIPTDEEVMIARDVLRLGNID
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5578_ARATH
Sequence: MTMYDLTDSGKDMCSSLCLLAEVAVMVAEEEQFRRLLKTVSKEEDSDKSFFYRFPRKIRSSLVKRRYTQQNPNGASTSSAVLDLNLITTDYDLKTQQNPSFDEPLVGLGKTEKKNLTNPNYQSSSSSSCLTENKSRKRRAVQQRKSGKLKKARVVSLPRMSIETPEWVFQVMRYMNADAETPRLIFERTLFNSDVKSGLSRLLIPFQQLIRNDFLTPAECRAIQKDEDNEDDKNIGVGTILVNQRSKMWGLRFKIWAMEKDSGHGTLNYILNWGWNDVVKGNGLKAGDNISLWTFRCRGVLCFPLET
What are the official names of this protein?
Putative B3 domain-containing protein At5g35780.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPE_HELPJ
Sequence: MISLIEKAPYIPYPLALYEKLEQRHTLLFESAEIESKAHTKSLLMAKACLKLVCNHNIVTITSLTPNGGAFLQTLSAFFKTPIQDNALTLTYTKDKKIQDEFLKLFEPSPFDALRGLFKSVKTRPKHPFTLFSAGVFSFEMLNFFEDLPHLKANDNTANDFIFYVAQNLIIIDHKEKSAEILGACFDERFKTEIAKELQDLKELVKNIKSDFIPKKAKQSIEVSVSCDDSEFEKKVLFLQEEIKKGEIFQAVLSRSFYMECLEGLSAYYHLKLSNPSPYMFYIKDSDFILFGASPESALKYNALTNTAEIYPIAGTRLRGKDKQGNIDYDLDSKMEFDLQHDYKERAEHIMLVDLARNDMARVSKKRYCDKLLKVDKYSNVMHLVSRVVGELKKGCDSLHAYRSFMNAGTLSGAPKISAIKLIYQLENQRRGSYGGSVGYLNSEGSMDSCITIRSCFVKNNRAVIQAGAGIVLDSVPQNEANETRAKVQALIDAIRKTIS
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: CO4A1_MOUSE
Sequence: MGPRLSVWLLLLFAALLLHEERSRAAAKGDCGGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPHGPPGQKGDAGEPGLPGTKGTRGPPGAAGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFSGNPGPPGLPGMKGDPGEILGHVPGTLLKGERGFPGIPGMPGSPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGSSFQGPKGDKGEQGVSGPPGVPGQAQVKEKGDFAPTGEKGQKGEPGFPGVPGYGEKGEPGKQGPRGKPGKDGEKGERGSPGIPGDSGYPGLPGRQGPQGEKGEAGLPGPPGTVIGTMPLGEKGDRGYPGAPGLRGEPGPKGFPGTPGQPGPPGFPTPGQAGAPGFPGERGEKGDQGFPGVSLPGPSGRDGAPGPPGPPGPPGQPGHTNGIVECQPGPPGDQGPPGTPGQPGLTGEVGQKGQKGESCLACDTEGLRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGLEGLPGPQGSPGLIGQPGAKGEPGEIFFDMRLKGDKGDPGFPGQPGMPGRAGTPGRDGHPGLPGPKGSPGSIGLKGERGPPGGVGFPGSRGDIGPPGPPGVGPIGPVGEKGQAGFPGGPGSPGLPGPKGEAGKVVPLPGPPGAAGLPGSPGFPGPQGDRGFPGTPGRPGIPGEKGAVGQPGIGFPGLPGPKGVDGLPGEIGRPGSPGRPGFNGLPGNPGPQGQKGEPGIGLPGLKGQPGLPGIPGTPGEKGSIGGPGVPGEQGLTGPPGLQGIRGDPGPPGVQGPAGPPGVPGIGPPGAMGPPGGQGPPGSSGPPGIKGEKGFPGFPGLDMPGPKGDKGSQGLPGLTGQSGLPGLPGQQGTPGVPGFPGSKGEMGVMGTPGQPGSPGPAGTPGLPGEKGDHGLPGSSGPRGDPGFKGDKGDVGLPGMPGSMEHVDMGSMKGQKGDQGEKGQIGPTGDKGSRGDPGTPGVPGKDGQAGHPGQPGPKGDPGLSGTPGSPGLPGPKGSVGGMGLPGSPGEKGVPGIPGSQGVPGSPGEKGAKGEKGQSGLPGIGIPGRPGDKGDQGLAGFPGSPGEKGEKGSAGTPGMPGSPGPRGSPGNIGHPGSPGLPGEKGDKGLPGLDGVPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEQGVPGRGFPGFPGSKGDKGSKGEVGFPGLAGSPGIPGVKGEQGFMGPPGPQGQPGLPGTPGHPVEGPKGDRGPQGQPGLPGHPGPMGPPGFPGINGPKGDKGNQGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGLPGVPGFQGQKGLPGLQGVKGDQGDQGVPGPKGLQGPPGPPGPYDVIKGEPGLPGPEGPPGLKGLQGPPGPKGQQGVTGSVGLPGPPGVPGFDGAPGQKGETGPFGPPGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTTDDPLCPPGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYSYWLSTPEPMPMSMAPISGDNIRPFISRCAVCEAPAMVMAVHSQTIQIPQCPNGWSSLWIGYSFVMHTSAGAEGSGQALASPGSCLEEFRSAPFIECHGRGTCNYYANAYSFWLATIERSEMFKKPTPSTLKAGELRTHVSRCQVCMRRT
What is the function of this protein?
Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation.  The C-terminal half is found to possess the anti-angiogenic activity.  Specifically inhibits endothelial cell proliferation, migration and tube formation.
What are the official names of this protein?
Collagen alpha-1(IV) chain.
What is the protein family that this protein belongs to?
Belongs to the type IV collagen family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix, basement membrane.
Protein: CPNE3_MOUSE
Sequence: MAAQCVTKVELNVSCNNLLDADVTSKSDPLCVLFLNTSGHQWYEVERTERIKNSLNPKFSKTFVIDYYFEVVQKLKFGIYDIDNKTIELSDDDFLGECEVTLGQIVSSKKLTRPLVLKNGKPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGHWLMVHRTEVIKNNLNPMWKPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEYECINEKKRQKKKSYKNSGVISVKHCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPSSPDSLHYISPNGVNEYLTAIWSVGLVIQDYDADKMFPAFGFGAQVPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRTCLPQIRLYGPTNFSPIINHVARFAAAATQQQTASQYFVLLIITDGVITDLDETRQAIVNAAKLPMSIIIVGVGGADFSAMEFLDGDGGSLRAPSGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPAVK
What is the function of this protein?
Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation.
What are the official names of this protein?
Copine-3, Copine III.
What is the protein family that this protein belongs to?
Belongs to the copine family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cell membrane. Cell junction. Cell junction, focal adhesion. Note=Associates to the membrane in a calcium-dependent manner. Translocates to the cell membrane and the nucleus in a calcium- or growth factor heregulin-dependent manner. Colocalizes with the tyrosine phosphorylated ERBB2 form at cell membrane and focal adhesions in a calcium- or growth factor heregulin- dependent manner.
Protein: VKT1_DABRR
Sequence: MSSGGLLLLLGLLTLWAELTPISGHDRPTFCNLAPESGRCRGHLRRIYYNLESNKCKVFFYGGCGGNANNFETRDECRQTCGGK
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor 1, Kunitz protease inhibitor 1, Kunitz protease inhibitor I.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYH_LEPBA
Sequence: MKEQKLTTENYKGTRDFYPEDMRLRNYLFSVMKDVVRSYGYEEYDGPMVESLDLYRAKTGEEIVGKQIYNFIDKGDREVAIRPEMTPTVARMVAKKLRELPRPIRWFSIPNLWRYEQPGHGRLREHWQLNVDMFGVTSSRAELEILSLACDILFAFGAPKNSFKVTISHRSLLDEFLLDGLKVSPNQAHEVSKILDKKNKITQDEYVALVTKTIPNDSSAVSKIDLFLNATVNSLNQIPGIKEETLAAIKGLFEDIKTIGLSDIIHFDPSVVRGFDYYTGFIFEIFDTSPQNKRSLYGGGRYDNLIGLFSNEELTGIGFGLGDVTLQNFLTAHNLLPNFASDTTVFIPLLDDSSFAENHNFAKELRKEKISAEVSLVSQKMGKQLSYAEKKGYRWILLRGEDEIKTNTVTLKDMASRNQFTFSFSEALQKIKEELSK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAG_SULIN
Sequence: MKYDIKLRFEVEGIVEKTDVIGAIFGQTENLFGDEFDLRELQDKGRLGRIIVEIRTKGGKSEGEIIIPSNLDRIETALIAAMVESVDKVGPYNSKFELIEIEDIRAEKLKKIIERAKGILSSWSKEKSLDIKEVINEISSAVKVGEITEYGPERLPAGPDVDKDPNLIIVEGRADVINLLRYGYKNVIAVEGATSRIPETVVSLSKMKKTVIAFLDGDHGGDLILKELLSNNVKIDFVARAPVGREVEELTGKEIAKALSNMMPLTQYLKKIQEAEQAIAKNVIAKEEKPIQLEATQQLVQITLPQNVLEEIKKLPGTLEGVLYDNNWNLIEKVQVRDIIPKLEAYEDNKVAYIVFDGVITQRLLDLASQKNIKMIIGARIGGINKRPQNVDILTFTDIISS
What is the function of this protein?
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Also part of the exosome, which is a complex involved in RNA degradation.  Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome.
What are the official names of this protein?
DNA primase DnaG.
What is the protein family that this protein belongs to?
Belongs to the archaeal DnaG primase family.
Protein: HBA_HEMAK
Sequence: MVLSSQNKKAIEELGNLIKANAEAWGADALARLFELHPQTKTYFSKFSGFEACNEQVKKHGKRVMNALADATHHLDNLHLHLEDLARKHGENLLVDPHNFHLFADCIVVTLAVNLQAFTPVTHCAVDKFLELVAYELSSCYR
What is the function of this protein?
Involved in oxygen transport from gills to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DSBD_CAMJR
Sequence: MRIFGIILLSFCLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKLKLYINEKDISSLINLPQSSTRGNENVYYQKLNLALPNLLLERFAKNTTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKDAFEISKPYKAQKTDKKTKIESEESSIANFLATDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIVAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGASIQGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIANTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFGFVMLAMAIWILSRIIEENYILIAYGILGVFFSVFMGIFEKSFTIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISASKHALSYDYINNFEQLKQEIQTNTKPIMLDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSENNNEQIKTMKEFNVFGPPVLIFFENGKEKLKITGFISADDLLKKIEP
What is the function of this protein?
Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes.  Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm.  This transfer involves a cascade of disulfide bond formation and reduction steps.
What are the official names of this protein?
Thiol:disulfide interchange protein DsbD, Protein-disulfide reductase, Disulfide reductase.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. DsbD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SGF11_PICST
Sequence: MTEQPITLDLVDIVDNIVRKQTLSSFARHVSVQSQTLGNHDTNVPVISNFAVGSNKDIFNQDKTKLKTSEASRYFSCENCGRKIAGGRYAQHVNKCLERRRR
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
What are the official names of this protein?
SAGA-associated factor 11.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSLU_RICTY
Sequence: MKSTETTCKKDNMGLTPSQIVNELNRFIVGQDKAKKAVAIALRNRYRRKRVEGNLRNEIVPKNILMIGSTGVGKTEIARRLAKLTNSPFYKIEATKFTEVGYVGRDVESIIRDLVEIAVNTEKALAKIAVDINAREKAIERILDSLVGKTSSSETREKFKEKVLNGELDDTEIEISVADTTPVGGGSFEIPCIPGASMGVLNLGDMIGRALGSSKTKTKKMLIKDAMTVIIPEESEKLIDQEKIIQKAINLAENDGIVFIDEIDKIASTSNSGAKNAEVSREGVQRDLLPLIEGTTVNTKYGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELNLLTKDDMIKILLEPETSLIKQYSALIGTEEVHLEFTDSAIEKIADYAITVNLEVEDIGARRLHTILENLLEDISFEASEMKVKKIIIDDKFVENQLSKIITNLDLAKFVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.