PharMolix/UniProtQA huggingface dataset:
Protein: PO5F2_HUMAN
Sequence: MAGHRPSNHFCPLPGSGGGGPRGPMPLRVDTLTWLSTQAAPGRVMVWPAVRPGICPGPDVWRIPLGPLPHEFRGWIAPCRPRLGASEAGDWLRRPSEGALPGPYIALRSIPKLPPPEDISGILKELQQLAKELRQKRLSLGYSQADVGIAVGALFGKVLSQTTICRFEAQQLSVANMWKLRPLLKKWLKEVEAENLLGLCKMEMILQQSGKWRRASRERRIGNSLEKFFQRCPKPTPQQISHIAGCLQLQKDVVRVWFYNRSKMGSRPTNDASPREIVGTAGPPCPGAPVCFHLGLGLPVDIPHYTRLYSAGVAHSSAPATTLGLLRF
What is the function of this protein?
Transcription factor that binds preferentially to the octamer motif (5'-ATGTTAAT-3').  May exert a regulatory function in meiotic events that are required for terminal differentiation of male germ cell (By similarity).
What are the official names of this protein?
POU domain, class 5, transcription factor 2, Sperm 1 POU domain transcription factor, SPRM-1.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-5 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: FIMB_PORGN
Sequence: MNDAKKYIVSVLILLVAGMFGGCIKEDYSDCPRPFRLTVRAWDADMQDITETGAVQRVVIFVFDETGRRIDRLMMDAAQVAARKPIPLEYDGPTTVSFVAWANPDDHMLEETANVQNVKDLFFRLSSTDGIAQSPGDLFSGVLTCPIEYGSIEQGTDQTVDIYRRTAQVHIIIRGYQEWLDANGPRQLPDYADILLGETPDTYTGLAELIGNAVQYRPDGQIQNGDFISPIFRVYPTLDTTPLHLKLYAYGQELLNISTGSDGVPFIPVIGKMLNIYIDLRGANLNVLVSVTPWDVVQQQQYAEY
What is the function of this protein?
Anchoring subunit of the major fimbriae.  Regulates fimbrial length (PubMed:20530728).  These filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome.  Fimbriae of P. gingivalis are major virulence factors.
What are the official names of this protein?
Major fimbrium anchoring subunit FimB.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. FimB/Mfa2 family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: 3S1E3_MICPY
Sequence: LICFNDFSPTARTLEYCQIGITTYNPS
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Weak neurotoxin E3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYDND_ACIC1
Sequence: MIRTHEAGTLRPADAGSRVVLAGWVARRRDLGGVVFLDLRDASGIVQVVAREGVAGQVASRVRAEFCLRVAGEVRLRPAGNENPELETGDVEVVADEIEVLSEAAPLPFPVTGPVEVNEETRLKYRYLDLRRPGPARALRLRSEMNRLAREVMARHRFVEVETPYLTRSTPEGARDFLVPARLQPGHWYALPQSPQLFKQLLMVAGLERYYQLARCFRDEDFRADRQPEFTQLDIEMSFVTEDDVMALAEDVIATLWSQLAGVELALPLPRLTYAEAMRRFGSDKPDLRFGQEIVDLTKFFAGTSLRIFQAPYVGAVVMPGGAGQSRSELDEWTTFARSRGAKGLAYVLVGAELTGPIAKNLSDAERAGLPAATGARPGDAIFFAAGEQRASQELLGAVRLEIARRCRLTDPASGAPAWSLCWIVDPPLFEPDGAGGWTSVHHPFTAPKPEWMDRFADKPGEALAAAYDIVANGNEIGGGSIRIHRADVQQRVFEVLGISEAEANAKFGFLLEAFRYGPPPHGGIAFGWDRIAALLAGVESIRDVIAFPKTASGTDPLTGAPTPITPEQRKEAGIDADPYAAAGRPPGRQSA
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_STRT2
Sequence: MSRYTGPSWKQSRRLGFSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLSEKQFRNLFVQATKVKGGTLGFNFMILLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVEVGQVISVREKSAKVPAILEAVEATIGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YAJR_ECOLI
Sequence: MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQGASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIWGIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITHKLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLNFGIMCLHILLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRKMKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAGYKGTAMGVYSTSQFLGVAIGGSLGGWINGMFDGQGVFLAGAMLAAVWLTVASTMKEPPYVSSLRIEIPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFEIEQAIRQA
What are the official names of this protein?
Inner membrane transport protein YajR.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL2_METPB
Sequence: MALKTFKPVTPSLRQLVLVDRRELYKGKPVKALTEGKSSSGGRNNLGRITVRFRGGGHKRVLRNVDFKRRENLNVPATVERIEYDPNRTAFIALITFPDGKQSYILAPQRLSPGDKVVAGESVDVKPGNAGPIGSMPVGTIVHNVELKIGKGGAIARSAGNYAQIVGRDQGYVTLRLNSGEQRLVHGQCFASVGAVSNPDHMNISLGKAGRNRWLGKRPHNRGVAMNPVDHPHGGGEGRTSGGRNPVTPWGVPTKGKKTRSNKRTDTFILSSRHNRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SMTA_BRAOT
Sequence: MVTGNTKAETFYSMKELLKETGGYAIIDGGLATELERHGADLNDPLWSAKCLLTSPHLIHTVHLDYLEAGADIISSASYQATIQGFEAKGYSIEKSESLLRKSVEIACEARSTYYDKCKDDDDKKILKKRPILVAASVGSYGAFLADGSEYSGIYGDLITLETLKDFHRRRVQVLAESGADIIAFETIPNKLEAQAFAELLDEGVAKIPGWFSFNSKDGVNVVSGDSIKECIAIAEACEKVVAVGINCTPPRFIEGLVLEIAKVTSKPILVYPNSGERYDPERKEWVENTGVGNEDFVSYVEKWMDAGVSLLGGCCRTTPTTIRAIHKRLVSRRSLFSSSSSSSHH
What is the function of this protein?
Catalyzes the methylation of DL- and L-selenocysteine with S-methylmethionine as donor.  Methylates also DL-homocysteine, DL- and L-cysteine in vitro.  May be involved in selenium detoxification.
What are the official names of this protein?
Selenocysteine Se-methyltransferase, BoSMT.
Protein: AROD_SHIBS
Sequence: MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVACAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: DNAK_CALS4
Sequence: MGKVIGIDLGTTFSCVAVMEGGQPVVIPNSEGTRTTPSVVAFTKEGERLVGHPARRQAIINPERTIMSIKRHMGTDYKVKIDDKEYTPQEISAMILQKLKADAEAYLGEKVTQAVITVPAYFNDSQRQATKDAGRIAGLEVLRIINEPTAAALAYGLDKEGNQKVMVYDLGGGTFDVSILEIGDGVFEVLATSGNNHLGGDDFDQRIIDWLADNFQKEHGIDLRKDRMALQRLKEAAERAKIELSSAMVTNINLPFITADASGPKHIDVNLTRAKFEELISDLVESTVGPVKQALSDAGLKPEDIDKVLLVGGSTRIPLVQETVKKIMGKEPHKGINPDEAVAIGAAIQAAVLAGEIKDILLLDVTPLSLGIETLGGVFTKIIERNTTIPVRKSQIFTTAADNQTSVEIHVLQGERPLAKDNKSLGRFILSGIPPAPRGVPQIEVTFDIDANGIVHVSAKDLATGKSQQITITGSTNLSEEEIQRMINEAKQYEEQDRKKREEIEIRNRADSLIYQAEKTMKDLGDKMTQAEKDEINKEIENVRKALEGTDVEAIKAASEKLSEAFYKVSTRLYQQAAGSANPGGSQGTSQGNVYEADYKVEDDNK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: HIS5_NOSS1
Sequence: MPVVAVIDYEMGNLHSVCKGLEKAGATPIITHCHQELTKADAVILPGVGAFDPAVQSLRSRDLEQPIKDTIASGKPFLGICLGLQILFESSAEGNQPGLGIIKGKVRRFVWEPGITIPHMGWNQLELTQPKSILWEHLPPQPWVYFVHSYYVDPFEPQVRAATVTHGTQTVTAAIAHENLMAVQFHPEKSSNIGLQILSNFVSQVREKIAA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DESM_PIG
Sequence: MSQAYSSSQRVSSYRRTFGGAPSFPLGSPLSSPVFPRAGFGTKGSSSSVTSRVYQVSRTSGGAGGLGPLRASRLGATRVPSSSYGAGELLDFSLADAVNQEFLTTRTNEKVELQELNDRFANYIEKVRFLEQQNAALAAEVNRLKGREPTRVAEIYEEELRELRRQVEVLTNQRARVDVERDNLLDDLQRLKAKLQEEIQLKEEAENNLAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVEMDMSKPDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEYRHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQDLLNVKMALDVEIATYRKLLEGEESRINLPIQTFSALNFRETSPEQRGSEVHTKKTVMIKTIETRDGEVVSEATQQQHEVL
What is the function of this protein?
Muscle-specific type III intermediate filament essential for proper muscular structure and function.  Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity.  In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures.  May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction.  Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult.  Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin.
What are the official names of this protein?
Desmin.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm. Cell membrane, sarcolemma. Nucleus. Note=Localizes in the intercalated disks which occur at the Z line of cardiomyocytes. Localizes in the nucleus exclusively in differentiating cardiac progenitor cells and premature cardiomyocytes.
Protein: TMA7_ANOFN
Sequence: MSGREGGKKKPLKAPKKEQSEMDDDDVAFKQKQKEQQKALDAAKQKASKGGPLLQGGIKKSGKK
What are the official names of this protein?
Translation machinery-associated protein 7 homolog, Coiled-coil domain-containing protein 72 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMA7 family.
Protein: RS17_YERPP
Sequence: MTDQIRTLQGRVVSDKMEKSMVVAIERVVKHPIYGKFIRRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAIL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: EFTS_VESOH
Sequence: MKITASLVKKLRQRMGAGMMDCKKALNATNGNIEKAIDLMRTLNTTKSAKKLDRITIEGLVKINISANKKTVTILEVNSETDFVTKSDTFISFVNMLGVLALKTTPTNIEEFLSQPLSNGDSIEKAREEIIAKVGENITIRRVQTIKTNNGIIGTYKHMDRIAVVTILEKGDETLAKDIAMHIAATNPECITEAELSSDLLEREKAIFIEQSKKSGKPNNIIEKMIIGRMKKFVNGVTLYGQPFIKNHDTTIGKLMQLNNTQVKFFVRFEVGEGIEKKEKNFVDEVMAQI
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXC_CHLTB
Sequence: MLGRAQRTLKRKVCYSGVGVHFGKAAMLTLEPAEENTGVVFSRHAASEQYIPARLANVCGTGRSTTLSLDGSVISTVEHLLASLYSFGVDNVRIYCSEDEIPIGDGSAQVFMDLIDQAGIQEQEQTVQIARLAHPVYYQYQDTILAAFPSDEFKISYTLHYSHNSTIGTQYRSLVISEESFRKEIAPCRTFALYSELCFLMEKGLIGGGCVGNAVLFKDDGVISLGKLRFPDEPVRHKILDLIGDLSLVGTPFLAHVIAVGSGHSSNIALGNRILEALQHEQELVK
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: PPE17_MYCTU
Sequence: MDFTIFPPEFNSLNIQGSARPFLVAANAWKNLSNELSYAASRFESEINGLITSWRGPSSTIMAAAVAPFRAWIVTTASLAELVADHISVVAGAYEAAHAAHVPLPVIETNRLTRLALATTNIFGIHTPAIFALDALYAQYWSQDGEAMNLYATMAAAAARLTPFSPPAPIANPGALARLYELIGSVSETVGSFAAPATKNLPSKLWTLLTKGTYPLTAARISSIPVEYVLAFVEGSNMGQMMGNLAMRSLTPTLKGPLELLPNAVRPAVSATLGNADTIGGLSVPPSWVADKSITPLAKAVPTSAPGGPSGTSWAQLGLASLAGGAVGAVAARTRSGVILRSPAAG
What is the function of this protein?
During M. tuberculosis and HIV-1 co-infection, can stimulate transcription from the long terminal repeat (LTR) of HIV-1 in monocyte/macrophage cells.  Interaction with human TLR2 activates the NF-kappa-B transcription factor, which binds to the promoter region of the HIV-1 and induces HIV-1 gene expression.
What are the official names of this protein?
PPE family protein PPE17.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PPE family.
What are the subcellular locations of this protein?
Secreted, cell wall. Cell surface. Note=Not secreted but surface exposed. Mainly localized in the cell wall fraction regardless of PE11 co- expression.
Protein: YS14_CAEEL
Sequence: MGVEISLDPPVCPIQANGGVSKHKMINHTDRHMAYKVKSSNNSNYSVNLIYGILKVCDVKELVITRKPGKPQADKLIIQYCMVVDENTDPKPLFANGVPPGELSGETVIKLSAAE
What are the official names of this protein?
Uncharacterized protein ZK1307.4.
Protein: OAPB_HAEIN
Sequence: MLKKTSLIFTALLMTGCVQNANVTTPQAQKMQVEKVDKALQKGEADRYLCQDDRVVRVVHATHKKYKKNLHYVTVTFQGVSEKLTLMISERGKNYANIRWMWQERDDFSTLKTNLGEILATQCVSQTSERLSGQ
What are the official names of this protein?
Opacity-associated protein OapB.
Protein: RSMG_ACIB5
Sequence: MHPFFQELQQGSQKLGLSLSDEALTLLLKYQDALVLWNKAYNLTAIRDPKEMLVKHLLDSLSILKDLPAGRLLDVGTGGGMPGMIIALCQPERSCVLLDSNGKKIRFLKQFIADLKLKNVIAVQTRVENQDTIDELGQFDVITSRAFASLTDFVEAARPYLHEQSIIAAMKGLIPVEEMEELKQEFSCKVIELHVPRLDEQRHLLLLQRI
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALL28_VIGMU
Sequence: GRREDDYDNLQL
What are the official names of this protein?
Major 28 kDa allergen.
Protein: LEPA_DESHY
Sequence: MAQASQCIRNFSIIAHIDHGKSTLADRLIEYTGALSKREMEAQVLDNMDLERERGITIKLQTVRLQYPAKDGQTYELNLIDTPGHVDFTYEVSRSLAACEGALLIVDAAQGIEAQTLANVYLALENNLEIIPVINKIDLPSAEPERVKQEIEDVIGLDASEAILASAKTGIGIEDILEAVVAKVPPPQGDDNTPLKALIFDSYFDAYKGAISYVRVMEGRVAKGTQIKMMSSGKVFDVTEVGMFTPALRIVDEIKAGQVGYIAASIKNVRDTQVGDTITDAENAALYPLPGYRKATPMVFCGLYPVDSSDYGRLKDALEKLHLNDSSLVFEPETSSALGFGYRCGFLGLLHMDVIQERLEREYDLNLITTAPSVVYKVNKTDGEVLSIDNPSNLPKVDEIETIEEPIVKANIMVPSDFVGAIMELNQEKRGNFLNMDYLSANRVTLHYELPLSEIVYDYFDQLKSRTKGYASLDYELAGYKAASLVKLDVLLNGELVDALSFIVHKEKSYARGRRLVEKLRGIIPRQMFEVPIQAVIGQKVVARETVKAMRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKQVGSVEIPQDAFMAVLKIDD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FDB3_FUSPC
Sequence: MSSKRLSQNEQEKSPGTGPPTHKRRRIGLACNACRMRKSRCDGHRPSCSSCLSLGVNCLYEPGDSTTNVIVRKDYVSDLEQRVASVEHNLQRLNDVLKGHLSPCTGGTDSNNHHNNHDSPCHQPTIAQSITSSRPNTRDKSAANETCATGLEEPDDEDANTNGMAMTFVEEKTSVYYGEASNINFTQLLLRALATVHGATPVAPSASNQASGPGDGVTTDVPQNQHAVSASDLATSESSPTALPSVQEMDSLLDIYFDTAGVVFPFICEDTMRRTYNECRHNGFTRARRTWLGTLNMIFALASCLSSSAKVRFERCNVFYKRAMALCGELSKRVVSLEIVHYLILVVLHCQGTQRSIQAWNNHGLAIRSAMALGLHCQSSGVSLDSAQQEYRRRTWVIIYCLDKVLSTAFGRPASIADEQMHSFNGRESVMGLSPMSLSNPQVPVDLPGDFLSVSFRLYQVMSKSLAEQYGTNLDHVDSGHDDMAPLKASGELRKQLRLWAGSLPGHLHVCQPEDEFLAHNTRGNRLRVILTLRYHNLGILIHKPLLSTTIRHLFQAGNRMEAPPSYMIQLAMAEAHECLRSAQLTIDIVYAVISADPTPENNLGAWYFTLYYVFTASLVVSGRLLWAQHGQSIVDEVAVDHCKSLLSKAEEIFKKLDRKNSLVLSCLEYIARLARICSMKDVPPNHQNGSLDITSDTTNTASGVTDTMPLDEDGMDAFQLFAAEMFDPNIFKGFNLSPVEGVSFTDGIWEGFPCGG
What is the function of this protein?
Transcription factor; part of the Fusarium detoxification of benzoxazolinone cluster involved in the degradation of benzoxazolinones produced by the host plant (PubMed:25727347, PubMed:26828593).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (By similarity).  FDB3 controls the transcription of the FDB gene cluster in response to 6-methoxy-2-benzoxazolinone (MBOA) (PubMed:26828593).
What are the official names of this protein?
Transcription factor FBD3, Fusarium detoxification of benzoxazolinone cluster protein 3, FDB cluster protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: CAC1S_LITCT
Sequence: MDAMGSAAEEGTQKKKRRPLVPPPPRPPRALFCLGLQNPFRKFCINIVEWKPFEMIILLTIFANCVALAIFLPMPEDDTNSTNSVLEKVEYIFLFIFTIESFLKIVAYGFILHTDAYLRNGWNILDFTIVSVGVFSVLLEQISKLQGLPAPGKSSGFNVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMIPLLHIALLVLFMIIIYAIVGLELFSGKMHKTCYFKDTDITATVDNEKPAPCSSTGQGRQCSINGSECRGWWPGPNNGITHFDNFGFAMLTVYQCITMEGWTEVLYWVNDAIGNEWPWIYFVSLILLGSFFVLNLVLGVLSGEFTKEREKAKSRGAFQMLREQQAMDEDLRGYLDWITHAEVMDPDMEPRDGFSQLEEGGSETDSLYEIEGINKFIAFFRQWRLWHRLLRRKSRDLVKSRFFYWLVIIIILLNTVIIATEHHHQPDSLTKAQDIANEVLLALFTMEMIVKIYALGFQSYFMSLFNRFDSFVVCTGLLEVMLVASDIMSPLGISVLRCIRLLRIFKITRYWTSLNNLVASLLNSVRSIASLLLLLFLFMIIFALLGMQMFGGKFDFEDLEVRRSTFDTFPQALITVFQILTGEDWTAVMYNGIMAYGGPTYSGMSVCIYFIILFVCGNYILLNVFLAIAVDNLAEAENLTSAQKAKAEERKRKKLARANPDKTEEEKLLLAKKEQKAKGEGIPTTARLKIDEFESNVNEIKDPYPSADFPGDDEEEEPEIPISPRPRPLAELQLKEKAVPMPEASSFFIFSPTNKIRVLCHRIINATTFTNFILLFILLSSISLAAEDPIQPESFRNKVLSKLDIVFTVIFTTEIVLKMTAYGAFLHKGSFCRNSFNILDLSVVGVSLISMGIESSAISVVKILRVLRVLRPLRAINRAKGLKHVVQCLFVAIKTIGNIVLVTTLLQFMFSCIGVQLFKGKFYSCTDTTKITADECRGYFFVAKDGNPAHMEAVPRVWSHSDFHFDNVLSGMMSLFTISTFEGWPQLLYRAIDSHAEDMGPIYNYRIEIAVFFIVYIILIAFFMMNIFVGFVIVTFQEQGEQEYKDCELDKNQRQCVQYALKARPLRRYIPKNPHQYKIWYVVTSSYFEYLMFFLITLNTISLGMQHYGQTAEFSYMSDILNVAFTGIFTVEMFLKLAAFKAKGYFGDPWNVFDFLIVIGSVIDVILSEIDTPGIPATPGAEESSRISITFFRLFRVLRLVKLLSRGEGVRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALVDGTHINRNSNFQTFPQAVLLLFRCATGEAWQEILLACSYGKLCDPMSDFQPGEEYTCGTSFAYFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVSMNMPLNSDGTVTFNATLFSLVRTALKIKTEGNFEQSNEELRMIIKKIWKRTSMKLLDQVIPPIGDDEVTVGKFYAIFLIQEHFRKFKKRQEEYYGYRPKKNANNVEIQAGLRTIEEEEGEGELQRAISGDLTPEEELERAMVEAAIEEGIYRRTGGLFGQEDSFHTGPVSPLHTITSQRPLRFSEAGSEDLDSPVFLPEPVFFPPPRRNRNTNNSTISRGLDQRLTTPDFERVQQSEEQWDTNSSISQATN
What is the function of this protein?
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, gene expression, cell motility, cell division and cell death.  The isoform alpha-1S gives rise to L-type calcium currents.  Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group.  They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines.  Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle (By similarity).
What are the official names of this protein?
Voltage-dependent L-type calcium channel subunit alpha-1S, FGalpha1S, Voltage-gated calcium channel subunit alpha Cav1.1.
What is the protein family that this protein belongs to?
Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EXC6_CAEEL
Sequence: MTSDTIRQTLDELLLDKNGGSSNEARAFFLSQIIDQLKLISSQTDAERQLQKLQLKDPNDNIVKATPPPPPPPPPLISILQQAPPPPPPPPPPTLKAPPPPPILGLKTPSKSLKTPTPRPKECPTSFLPKKEKKTKTRTVQWSKINASVVQDDSVWGKLAKASNVDIDFDLLDNFFGIESLAVSGAAEVVKKSTRKDAHVELLTAKRSQNVAIMLKQFKNIDELIDDVSQNKPVAEIDALQNLFGMLPQSEEEEALRRYTGDISLLSPPSSFFYRLVQIQFYRLRIETQIFLSDFSRLMRELAPNVEILIRTSQEILTSPTLPRLLLIFVNMGNYLNGNNSQGNAFGFTLNSLWKLIDLKGNKQEFSLLHLLVTCEPDLVAHLQEELSTLKDASQISFDEIKISLKTLRDGRCKLEKQLETCSGASFTQFLELIKIDCKFELDEFGANYDKLTELQYQLADYFCENRNTFQLDECLKIFNFLMNRLQQTLKEHVTRETRKLKKEEKKETQTTRECEKTMKKPEKIDLFDALTASNGGPESPRKRAAGILDMRQKLGNVRIRKLRDVTTLESSFTPPPPPPLESPTDSTSSKENESVKPAKTSTNYEMCNDLESYITSLTRKRASHLPKAPPKEEPKLPEVLPEKSKIALKIEKIPEKIDKPPLPQAAPIIPKLPQKSIKAPSTVTTRSKVPPPTAAAAVRIVSVTTTTTPTKTAELRKPGARSPKTTVATVPKVTVVPVSRVPVAPSTPLSRRMSAPVVRKPTMTAEKKREITMKPSVSTSARPSLINTSSHPMVRSPLPKMSVLEKPKPLRITRPTVIPQSPTVTSSARPSGLRQPAKPKWV
What is the function of this protein?
Constitutively active protein required for microtubule and F-actin growth, structural maintenance and organization during excretory cell tubulogenesis.
What are the official names of this protein?
Excretory canal abnormal protein 6.
What is the protein family that this protein belongs to?
Belongs to the formin homology family.