PharMolix/UniProtQA huggingface dataset:
Protein: PMEL_CHICK
Sequence: MRLHGAIVLLAALLALVTAQQRGGGRSRGGVKGSAWGGRPAPFRSWDTARYRPWQEGTARQNDCWRGGDVTFDISNDAPTLVGARATFSIALRFPGTQTVLPDGRVVWSQNCTVNGTRMLQGDPVYPEQLAEGSDGVFPDGQPFPRSAWGKRGRFVYVWWTWGRYWQVVDGATSQLTVGTDGVALGSYTMEVVVYHYRGRQRFIPIGHASTQFSITDQVPIAVDVTQLEVAAGDGGSFVRNRPVAFNVRLHDPSHYLRDADISYSWDFGDQSGTLISRSPTVTHTYLQAGSFAARLVLQAAIPLSSCGTSAPPVVDPTTGPVPSLGPTATQPVGPTGSGTATAPSNLTGSGTAAAPGTTAAPRASGAPAEPTGVSVAVLSDSAATEPLPDPVLSTAVADAAAGTDPTADPLPPTSVSSGGDAPGTVAPTAVEGSVAAGVGTAEDVAAATPGATAADVAVDTAGATDGDAVGPTAAATAESIADPTAGATDGDAVGATAESIADPTAGATDGDAVGPTAAATAESIADPTAGATAVSSGSATAGATAEPLLLVKRQAPEAEPTGCVLYRYGTFSTELNIVQGIESVAIVQVVPAAPEGSGNSVELTVTCEGSLPEEVCTVVADAECRTAQMQTCSAVAPAPGCQLVLRQDFNQSGLYCLNVSLANGNGLAVASTHVAVGGASPAASGTTLTVGLLWAPLIAAALGTAAYTYRRVKYSPLLPTAPTAPRPHSWLPPGATLRLLLRQAFGGAPSGESSPLLRANAV
What is the function of this protein?
Might be required for polymerization of melanin onto the core structure of melanosomes with enzymatic function of tyrosinase.
What are the official names of this protein?
Melanocyte protein PMEL, 115 kDa melanosomal matrix protein, Melanocyte protein Pmel 17, Premelanosome protein, Silver locus protein homolog.
What is the protein family that this protein belongs to?
Belongs to the PMEL/NMB family.
What are the subcellular locations of this protein?
Melanosome lumen. Note=On the fibrous matrix structure of the premelanosome.
Protein: HIS7_STAEQ
Sequence: MNYQIKRNTEETQLNISLANNGTQSHINTGVGFLDHMLTLFTFHSGLTLSIEATGDTYVDDHHITEDIGIVIGQLLLELIKTQQSFTRYGCSYVPMDEALARTVVDISGRPYFSFNSKLSAQKVGTFDTELVEEFFRALIINARLTVHIDLLRGGNTHHEIEAIFKSFARALKISLAQNEDGRIPSSKGVIE
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGS1_YEAST
Sequence: MVTKPSHNLRREHKWLKETATLQEDKDFVFQAIQKHIANKRPKTNSPPTTPSKDECGPGTTNFITSIPASGPTNTATKQHEVMQTLSNDTEWLSYTATSNQYADVPMVDIPASTSVVSNPRTPNGSKTHNFNTFRPHMASSLVENDSSRNLGSRNNNKSVIDNSSIGKQLENDIKLEVIRLQGSLIMALKEQSKLLLQKCSIIESTSLSEDAKRLQLSRDIRPQLSNMSIRIDSLEKEIIKAKKDGMSKDQSKGRSQVSSQDDNIISSILPSPLEYNTSSRNSNLTSTTATTVTKALAITGAKQNITNNTGKNSNNDSNNDDLIQVLDDEDDIDCDPPVILKEGAPHSPAFPHLHMTSEEQDELTRRRNMRSREPVNYRIPDRDDPFDYVMGKSLRDDYPDVEREEDELTMEAEDDAHSSYMTTRDEEKEENELLNQSDFDFVVNDDLDPTQDTDYHDNMDVSANIQESSQEGDTRSTITLSQNKNVQVILSSPTAQSVPSNGQNQIGVEHIDLLEDDLEKDAILDDSMSFSFGRQHMPMSHSDLELIDSEKENEDFEEDNNNNGIEYLSDSDLERFDEERENRTQVADIQELDNDLKIITERKLTGDNEHPPPSWSPKIKREKSSVSQKDEEDDFDDDFSLSDIVSKSNLSSKTNGPTYPWSDEVLYRLHEVFKLPGFRPNQLEAVNATLQGKDVFVLMPTGGGKSLCYQLPAVVKSGKTHGTTIVISPLISLMQDQVEHLLNKNIKASMFSSRGTAEQRRQTFNLFINGLLDLVYISPEMISASEQCKRAISRLYADGKLARIVVDEAHCVSNWGHDFRPDYKELKFFKREYPDIPMIALTATASEQVRMDIIHNLELKEPVFLKQSFNRTNLYYEVNKKTKNTIFEICDAVKSRFKNQTGIIYCHSKKSCEQTSAQMQRNGIKCAYYHAGMEPDERLSVQKAWQADEIQVICATVAFGMGIDKPDVRFVYHFTVPRTLEGYYQETGRAGRDGNYSYCITYFSFRDIRTMQTMIQKDKNLDRENKEKHLNKLQQVMAYCDNVTDCRRKLVLSYFNEDFDSKLCHKNCDNCRNSANVINEERDVTEPAKKIVKLVESIQNERVTIIYCQDVFKGSRSSKIVQANHDTLEEHGIGKSMQKSEIERIFFHLITIRVLQEYSIMNNSGFASSYVKVGPNAKKLLTGKMEIKMQFTISAPNSRPSTSSSFQANEDNIPVIAQKSTTIGGNVAANPPRFISAKEHLRSYTYGGSTMGSSHPITLKNTSDLRSTQELNNLRMTYERLRELSLNLGNRMVPPVGNFMPDSILKKMAAILPMNDSAFATLGTVEDKYRRRFKYFKATIADLSKKRSSEDHEKYDTILNDEFVNRAAASSNGIAQSTGTKSKFFGANLNEAKENEQIINQIRQSQLPKNTTSSKSGTRSISKSSKKSANGRRGFRNYRGHYRGRK
What is the function of this protein?
ATP-dependent DNA helicase able to unwind duplex DNA or DNA- RNA heteroduplex (PubMed:9545297).  Displacement of the DNA strand occurs in the 3' to 5' direction with respect to the single-stranded DNA flanking the duplex (PubMed:9545297).  Acts as an integral component of the S-phase checkpoint response, which arrests cells due to DNA damage or blocked fork progression during DNA replication (PubMed:10640278).  Can create a deleterious topological substrate that TOP3 preferentially resolves.  The TOP3-SGS1 protein complex may function as a eukaryotic reverse gyrase introducing positive supercoils into extrachromosomal ribosomal DNA rings (PubMed:7969174).  Together with topoisomerase II has a role in chromosomal segregation (PubMed:7736577).  Maintains rDNA structure where it has a role in re-starting stalled replication forks (PubMed:12228808).
What are the official names of this protein?
ATP-dependent helicase SGS1, Helicase TPS1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecQ subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Localizes to S-phase-specific nuclear foci (PubMed:10640278).
Protein: CC195_HUMAN
Sequence: MEADIQLMRLIQEMRAEIHKLEKENQALRMKLTASSQRASGSGRESGDEREEEAPGQSPATLQGAVSTDAAPAVQEHQGNVMIVRRYSISSSVCSSAVNDPWKSGKSHPKSGILEGQRTLKSLACSPIKKQDMEEKVFATDSLTSNRTSQRASPEHVCGCRDKTKAVSFLLPMDMSSYSKNSSSLKHSPNQATNQLSIIAE
What are the official names of this protein?
Putative coiled-coil domain-containing protein 195.
Protein: DNLJ_ECO57
Sequence: MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEEDRPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEDTREVVFPTYCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTFARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAEESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVELGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PYRF_CAMJR
Sequence: MKLCVALDLSTKEECLQLAKELKNLDIWLKVGLRAYLRDGFKFIEELKKVDDFKIFLDLKIHDIPNTMADACEEVSKLGVDMINIHASAGKIAIQEVMTRLSKFSKRPLVLAVSALTSFDEENFFSIYRQKIEEAVINFSKISYENGLDGMVCSVFESKKIKEHTSSNFLTLTPGIRPFGETSDDQKRVANLAMARENLSDYIVVGRPIYKNENPRAVCEKILNKIHRKNISENDIEQNYEVIQQKEWDMCNHFEEWIKTQPDKEHALKEFYAKCGIKY
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SUCB_YEAST
Sequence: MYSRKSLSLISKCGQLSRLNAQAALQARRHLSIHEYRSAQLLREYGIGTPEGFPAFTPEEAFEAAKKLNTNKLVIKAQALTGGRGKGHFDTGYKSGVHMIESPQQAEDVAKEMLNHNLITKQTGIAGKPVSAVYIVKRVDTKHEAYLSILMDRQTKKPMIIASSQGGMNIEEVAERTPDAIKKFSIETSKGLSPQMAKDVAKSLGFSPDAQDEAAKAVSNLYKIFMERDATQVEINPLSEIEHDPTHKIMCTDAKFGFDDNASFRQEKIYSWRDLSQEDPDEVKAKKYDLNFVKLKGNIGCLVNGAGLAMATMDVIKLNGGDPANFLDCGGGATPETIKQGFELILSNKNVDAIFVNIFGGIVRCDYVALGLVEAARELEVRVPIVARLQGTKVEEGRDIINKSGVKIYSFDELDPAAKKVVELTQN
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:9874242).  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity).
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, Succinyl-CoA synthetase beta chain, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: AMY_STRLM
Sequence: MARRLATASLAVLAAAATALTAPTPAAAAPPGAKDVTAVLFEWKFASVARACTDSLGPAGYGYVQVSPPQEHIQGSQWWTSYQPVSYKIAGRLGDRAAFKSMVDTCHAAGVKVVADSVINHMAAGSGTGTGGSAYQKYDYPGIWSGADMDDCRSEINDYGNRANVQNCELVGLADLDTGESYVRDRIAAYLNDLLSLGVDGFRIDAAKHMPAADLTAIKAKVGNGSTYWKQEAIHGAGEAVQPSEYLGTGDVQEFRYARDLKRVFQNENLAHLKNFGEDWGYMASGKSAVFVDNHDTERGGDTLNYKNGSAYTLAGVFMLAWPYGSPDVHSGYEFTDHDAGPPNGGTVNACYSDGWKCQHAWPELSSMVGLRNTASGQPVTNWWDNGGDQIAFGRGDKAYVAINHEGSALNRTFQSGLPGGAYCDVQSGRSVTVGSDGTFTATVAAGTALALHTGARTCSGGGTGPGTGQTSASFHVNATTAWGENIYVTGDQAALGNWDPARALKLDPAAYPVWKLDVPLAAGTPFQYKYLRKDAAGKAVWESGANRTATVGTTGALTLNDTWRG
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: RL13_SACD2
Sequence: MKTISAKPETVKRDWYIIDADGKTLGRMAAEIAHRLRGKHKPEFTPHVDTGDYIVVINAEKVRVTGRKATDKMYYSHTGFIGGIKSISFEKLIDKAPERTIQNAVKGMLPRGPLGRAMFKKLKVYGGSEHPHTAQQPQELNI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TM9S4_MOUSE
Sequence: MAAAMIWWPRFLLLLCLTCKGSTFYVPGVAPINFHQNDPVEIKAVKLTSSRTQLPYEYYSLPFCQPIKITYKAENLGEVLRGDRIVNTPFQVLMNSEKKCEVLCNQSNKPITLTVEQSRLVAERITEEYYVHLIADNLPVATRLELYSSNRDSDDKKKEKDVQFEHGYRLGFTDVNKIYLHNHLSFILYYHREDMEEDQEHTYRVVRFEVIPQSIRLEDLKTGEKSSCTLPEGANSLPQEIDPTKENQLYFTYSVHWEESDIKWASRWDTYLTMSDVQIHWFSIINSVVVVFFLSGILSMIIIRTLRKDIANYNKEDDIEDTMEESGWKLVHGDVFRPPQYPMILSSLLGSGIQLFCMILIVIFVAMLGMLSPSSRGALMTTACFLFMFMGVFGGFSAGRLYRTLKGHRWKKGAFCTATLYPGVVFGICFVLNCFIWGKHSSGAVPFPTMVALLCMWFGISLPLVYLGYYFGFRKQPYDNPVRTNQIPRQIPEQRWYMNRFVGILMAGILPFGAMFIELFFIFSAIWENQFYYLFGFLFLVFIILVVSCSQISIVMVYFQLCAEDYRWWWRNFLVSGGSAFYVLVYAIFYFVNKLDIVEFIPSLLYFGYTTLMVLSFWLLTGTIGFYAAYMFVRKIYAAVKID
What is the function of this protein?
Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface.
What are the official names of this protein?
Transmembrane 9 superfamily member 4.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Golgi apparatus. Early endosome.
Protein: BIOB_BURM7
Sequence: MTEAQTACATTETPVAAPAAPRWRVADVIALYELPFNDLLFRAQQTHREHFDANAIQLSTLLSIKTGGCEEDCGYCSQSAHHDTGLKAEKLMEVDAVLAAARTAKENGATRFCMGAAWRNPKDRHIEPIKEMIRGVKDMGLETCVTLGMLEEHQAKALAEAGLDYYNHNLDTSPEFYGQIISTRTYQDRLDTLERVRDAGINVCCGGIIGMGESRRERAGLIAQLANMNPYPESVPINNLVAIEGTPLENAQALDPFEFVRTIAVARITMPKAMVRLSAGREQLDDAMQALCFLAGANSMFYGDVLLTTGNPRAEADRKLLARLGMSASEASQLSA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: RECR_FRATO
Sequence: MTSKIFSPKISAVIESLRKLPTIGKKSSQRLALYLLDKSPETAIAIANSLLDATANIKKCVYCQALTEDDVCNICSNTNRDDTKLCIIESMLDMIAIEEAGIYRGKYFVLNGRISPLDGIGPSELKLDILQQIIADRKIDEVILAISPTVEGETTAHFISQMIAKDIKISRIGFGVPFGGELEYLDQQTLLHAFNTRTNI
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: YL005_MIMIV
Sequence: MNKLKKIQMKETDYYFGNDIAQLNLPGLKKYTNGRRLVEDQGISNKHYMFVRHDGDSWIKSSDKSCKFDKIIIKADYVEKHIFPKKMKPNKDDDEEEDEDDEDDEDDEEEDNEEEDNEEENEITIAPGIIKLSKKEKMKDNSGNIIEIEVRGTRDHDNCYFRVSDVSVGFGMKKLHDTITKKGGYEENNHYRYFYIDKNPTNSGKSKKVKSKKPLPKKLFLTYLGLLKVLFVSRNKTVGNFLNWATETLFTAHLGTQDQKNELSSKLMGISANIVKEVFSTTSSTLPTIYLFSIGKVKDLRATLKIDKEYNDNDIVCKVGETIDLTRRINEHNATYGKLPGANLCLKWYNYIDPQHTSKAETELLMLLDKLGHKLDHPKYDELIIFPKDKKAGKFIIDQFKNVSNKYIGHVKVLVDKIKELENEIKELKYQNEINELKYKNIILEKDLEISNLNKKLKKKK
What are the official names of this protein?
Uncharacterized protein L5.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L5 family.
Protein: CPFC_STRZT
Sequence: MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYDNYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECICLILEPHYSFYSVMGYEKFLESQQIRFLVIKDWYQQQSLLDFWTDEIRKILRNEVGEESFKVIFSAHSVPIFALDYGDPYIDQIFDNSRLIAEQLGLMTDQYTNTWQSESDIGIPWIKPDVLEYLREQKQHPEHYIFVPISFISEHIEVLFDNDVECYDLCQELGVTYHRPPMPNTDSRLIDALVATVRANEDKEFKTFLPEEETFDELAPSATTKDIMKETDDLQMPEFVKKLIEKKGRENVKMPYLIKKMLEKAGKLPKE
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUXE_BOVIN
Sequence: MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.  As part of the U7 snRNP it is involved in histone 3'-end processing.
What are the official names of this protein?
Small nuclear ribonucleoprotein E, snRNP-E, Sm protein E, Sm-E, SmE.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: SAAL1_XENTR
Sequence: MDRNPSPPSSDDESAPEGDCIGDTIYSKHWFFSTLTRLIEAVSEDKSQEGQEDEAPGDLDEELEDEICKVWDMSMNEEVALFLQGFNAPEILLGVIAKSKCSRLTEMCVGILGNMSCFLEPCMAISTHQSLGEVLLLLLSDADPPTLLETSRLFLTCLSQADVAGTWVERFRKDPSVRENLCFIMSSSTNVDLLVKVGELLDRLFDMDEDLMLAWIRSDCAPRETSAVTENEDRAAPLEMVSCLLEAAKQLRSESPEGLEIYMHVLQLLTTADTGIQAIVQSPDGGEQTWDFLLDLTCNDLCQPNDPPLIVQEQKGILSSVLAVMSAMFVWRAEQGHKVEKSLPLISSLAQVLENLEECRKKCPESDAREGPDARHDNSHLQILKDVSCEFLSNILSELSKDSVLQGISLGHITERRCQCALRNLLPLYSTSVGTFLAAVGEADRSLADTLRRETPVRAEQT
What is the function of this protein?
Plays a role in promoting cell proliferation in response to pro-inflammatory stimuli.
What are the official names of this protein?
Protein saal1.
What is the protein family that this protein belongs to?
Belongs to the SAAL1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYM_BURVG
Sequence: MSATDLASVQAAAPQGSRQILVTSALPYANGQIHIGHLVEYIQTDIWVRTLRMHGHEVYYIGADDTHGTPIMLRAEMEGLTPKQLIDRVWAEHKRDFDSFGVSFDNFYSTDSDENRVLSEKIYVALKENGLIAEREIEQAYDPVKEMFLPDRFIKGECPKCHAKDQYGDSCEVCGSTYLPTDLLNPYSVVSGATPVRKTSTHHFFRLSDPRCESFLRDWVSGLAQPEATNKMREWLGDAGEAKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLCERKGINFDAWVRPGATAEQYHFIGKDILYFHTLFWPAMLEFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYIDTGLNPEWLRYYFAAKLNATMEDIDLNLDDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQDSAMNHPLVAKLRSAIDSIAAHYEAREYSRALRQTMELADEVNAYVDGAKPWELAKDPANAVALHETCSVSLEAFRLLSLALKPVMPRVAQAVEAFFGIAPLAWADAAKPLSSAQPINAYQHLMTRVDAKQIDALLAANRGSLQADGAAAAAASGATGAAAAKDAKPAKANAKAAAANAANDGPISIDDFAKIDLRIAKIVACQAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASAADEKAEPGLYILEPHSGAKPGMRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRP45_YARLI
Sequence: MTSITALLPAPRYPTPGPKMSIFTTNAVSMAKNDSVPKYGSRTDWKPTSQADFNDGGAYPEIHIAQYPRNMGKPGSVSSNAITLKMDASGSADYSLIATQGHAADRHVQTSYDSLIPLRERIDAGTVSLEKPGEEAEQSTALATQAAFDKRLAANDKSGTKNKSDPQYIRYTANSMMGTEGGESQKIIKMVDLPQDPLEPPKFKHTKVPGRPASPPAPILRSPPRKLTAQDQKDWAIPSTVSNWKNQKGFTISLDKRMAADGRGLEDVKVNENFAKFSEVLNQNEKTMRDDIGKRREMQQRVAERQAQEQEEKLRELARRARQEREVGDESKGKEKEADGEDDRGRSRERLRSVSRDGDSDRSLSRSLSASDRSYSRSRSPYESRSRGRSYSRSRSPESRFRGRSDSRSRSPGYELERAAKKRKTERLERKREAERDLRLSKMGTQQKIKQLAKENSRDISERVALGAAQPQKLAGEAQFDSRLFSKSGSLQRGFNEDQYYDKSLFSAQEAVQSIYRPSASGDSVAEDTIDRLETEKRFDVLGKAGKGFEGADGEERDGPVRFVRDEE
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-processing protein 45.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CMTR1_MOUSE
Sequence: MKRRTDPECTAPLKKQKRIGELARHLSSTSDDEPLSSVNHAAKASATSLSGSDSETEGKQPCSDDFKDAFKADSLVEGTSSRYSMYNSVSQRLMAKMGFREGEGLGKYSQGRKDIVETSNQKGRRGLGLTLQGFDQELNVDWRDEPEPNACEQVSWFPECTTEIPDSREMSDWMVVGKRKMVIEDETEFCGEELLHSMLKCKSVFDILDGEEMRRARTRANPYEMIRGVFFLNRAAMKMANMDFVFDRMFTNPLDSSGKPLLKESDIDLLYFADVCAGPGGFSEYVLWRKKWHAKGFGMTLKGPNDFKLEDFYSASSELFEPYYGEGGVDGDGDITRPENINAFRNFVLDNTDRKGVHFVMADGGFSVEGQENLQEILSKQLLLCQFLMALSVVRTGGHFVCKTFDLFTPFSVGLIYLLYCCFERVCLFKPITSRPANSERYVVCKGLKVGIDDVREYLFSVNIKLNQLRNTESDVNLVVPLMVIKGDHEFNDYMIRSNESYCSLQIKALAKIHAFVQDTTLSEPRQAEIRKECLQLWKIPDQARVAPSSSDPKFKFFELIKDTDINIFSYKPTLLTAKTLEKIRPVLEYRCMVSGSEQKFLLGLGKSQIYTWDGRQSDRWVKLDLKTELPRDTLLCVEIVHELKGEGKAQRKISAIHILDVLVLNGSDVREQHFNQRIQLAEKFVKAVSKPSRPDMNPIRVKEVYRLEEMEKIFVRLEMKLIKGSGGTPKLSYTGRDDRHFVPTGVYIVRTVNEPWTMGFSKSNNRKFFYNKKTQKSVYALPTESIAPFHTCYYSRLFWEWGDGFHMRDSQKPQDPDKLSKEDVLSFIQSHNPLGP
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs.  Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1).  Displays a preference for cap0 transcripts.  Cap1 modification is linked to higher levels of translation.  May be involved in the interferon response pathway.
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, Cap methyltransferase 1, Cap1 2'O-ribose methyltransferase 1, MTr1, FtsJ methyltransferase domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_LONFE
Sequence: MTNIRKTHPLAKIINDSFIDLPAPSNISTWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASLFFICLFLHVGRGLYYGSYMFPETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFTFHFILPFIILTLAVIHLLFLHETGSNNPSGIPSNSDKIPFHPYYTVKDALGALLLTLTLMTLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPSKLGGVLALVLSISILAIIPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFTILLILMPAVGIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NHAB_SHESR
Sequence: MPMTMSQAFIGNFLGNSPKWYKIAILSFLIINPILFFYVSPFVAGWVLVLEFIFTLAMALKCYPLQPGGLLAIQAVAIGMTSASQVLHEIEANLEVLLLLVFMVAGIYFMKQLLLFAFTKMITKVRSKILVSLMFCLASAFLSAFLDALTVIAVIITVAVGFYSIYHKVASGKDFSADHDHTSEGKNEDGENQLNEEELESFRGFLRNLLMHAGVGTALGGVCTMVGEPQNLIIAAQANWQFGEFAIRMSPVTVPVLFAGILTCFLVEKLRWFGYGAQLPEAVHKILCDYAAYEDARRTNKDKMKLVIQAFVGVWLIAGLALHLASVGLIGLSVIILTTAFNGITDEHALGKAFEEALPFTALLAVFFAVVAVIIDQQLFGPVIQWALNHEGNTQLVIFYIANGLLSMVSDNVFVGTVYINEVKAALINGQITRDQFDLLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLSIVGVMAIESGFLEQMTQYFYDSHAIIHHSVKEALAPAAAH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaB, Sodium/proton antiporter NhaB.
What is the protein family that this protein belongs to?
Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARCC_STAHJ
Sequence: MSKIVVALGGNALGQSPEEQLELVKGTAKSLVSLIQKGYEVVISHGNGPQVGSINLGLNYAAENGQGPAFPFPECGAMSQAYIGYQLQESLLNELHVLNIDKQVVTLVTQVEVAGDDQAFNNPTKPIGLFYTKEQAEQTMEEKGYKFVEDSGRGYRRVVPSPMPINIVELDSIETLIKHGTLVIAAGGGGIPVVKEEGNYKGVDAVIDKDKTSALLAAHLKSDQLIILTAVDYVYINYGKDNQEALGEVTVDEMNQHIADGQFAKGSMLPKVEAALQFIEKNPEGSVLITSLEDLGDALDGKIGTLIKK
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXB_RICFE
Sequence: MKITTKVLIIGSGPAGLSAAIYTARAALKPILINGMQPGGQLTITTDVENYPGFAETVQGPWLMEQMSMQAKNVGTEIISDYVEKVDLSKRPFKVFTGAGNEYEAESIIICTGAEAKWLSIASEQEFRGFGVSACATCDGFFFKNQEIVVVGGGNSAVEEALYLTNHASKVTITHRRDSFRAEKILQDRLFKNPKISVIWDHVVDEIVGSDKPKSVTGVKIQNVHTKEISLVNCSGVFIAIGHAPNTGLFTGQIAMDDDNYIITKSGTTKTSVEGVFAAGDVQDKIYRQAVTAAGSGCMAALEVEKFLNK
What are the official names of this protein?
Thioredoxin reductase, TRXR.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMR7_ARATH
Sequence: MGISKKSQVSRELDTDGKKFIFAKTSIRASLKPVKTKLIKPERESEDGICITPTARGAKTPECPAAPRKRPPVLKCQNNIRIEYFVPPSDFELVFIQRR
What is the function of this protein?
Probable cyclin-dependent protein kinase (CDK) inhibitor that functions as a repressor of mitosis in the endoreduplication cell cycle (PubMed:26546445).  Acts as a potent cell cycle inhibitor, regulating a hydroxyurea-dependent checkpoint in leaves (PubMed:24399300).
What are the official names of this protein?
Cyclin-dependent protein kinase inhibitor SMR7, Protein SIAMESE-RELATED 7.
Protein: GCST_IDILO
Sequence: MGSRTPLYEAHVKAGAKMVDFHGWDMPLNYGSQIEEHHAVRRDCGVFDVSHMTIVDVEGSQAQAFLRYLLANDVAKLKTEGKAQYTSMLNENGGVIDDLIVYFFSENAYRMVVNSATRDRDLAWIEKVAADFDVTTKERDDMGMLALQGPKAADKIQGVLTAEQYAEIDGMKPFVGKDVGDYFIATTGYTGEKGYEIVVPAEQLEALWNDLLKADVAPCGLGARDTLRLEAGMNLYGQDMDENITPLEANMGWSVAFEPADRDFIGRKALEQKKAEGHDKLVGLVMEEKGVLRHGQKVTVEGGEGIITSGTFSPTLGFSVAMARVPSSVGDTAEVEMRKKQMPVKVVKPGFVRNGQSVL
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.