PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_METC4
Sequence: MANTLVGRKRIRKFFGKIREVAEMPNLIEVQKASYDQFLMVDEPEGGRADEGLQSVFKSVFPISDFASTALLEFVRYTFEQPKYDVDECRQRGITFAAPLKVTLRLIVFDVDPDTGAKSVKDIKEQDVYMGDMPLMTDNGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHSSGKLLFAARIIPYRGSWLDVEFDAKDIVHVRIDRKRKLPVTSLLFALGLDGEEILSTFYNRVAYQRDGADWRVPFDAERLKGFKASVDLIDADSGEVVLEAGKKLNARNARLIGEKGTKFLRAADEDLIGQYIAEDLVNMKTGEIWAEAGDEISEKLLKSLDDVGVTELPVLDIDHVNVGPYIRNTLAVDKNSAREGALFDIYRVMRPGEPPTLDTAEAMFHSLFFDSERYDLSAVGRVKMNMRLDLDAADTVRTLRREDMLAVVKALVDLRDGKGEIDDIDHLGNRRVRSVGELMENQYRLGLLRMERAIKERMSSVDIDTVMPQDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATFARVNKYGFIETPFRRVKDGVVTDEVAYLSAMEEAKYYVAQANAGMDEGRKLTDDLVVCRRAGEVIVVAPDRVDLMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLVRADAPFVGTGMEAVVARDSGAAIAARRSGIVDQVDATRIVIRASEETDPTKPGVDIYRLQKFQRSNQSTCITQKPLVRVGEPVKKGEIIADGPSTEFGELALGRNVLVAFMPWNGYNFEDSILLSERIVKDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVSEEALKNLDEAGIVYIGAEVHAGDILVGKITPKGESPMTPEEKLLRAIFGEKASDVRDTSLRVPPGVTGTIVEVRVFNRHGVDKDERAQAIEREEIERLAKDRDDEQTILDRNTYARLAEVLIGQSPIAGPKGFRKDTTLTREIISEYPRSQWWQFAVVDDRMMTEIEAMQKQYDESKKRLEQRFLDKVEKLQRGDELPPGVMKMVKVFVAVKRKIQPGDKMAGRHGNKGVVSRIVPIEDMPFLEDGTHADIVLNPLGVPSRMNVGQILETHLGWAAAGLGRKVSKAVDAYLKNQDIAPLRAEMEAIYSPSELEGLSDEALAEAGNNVRRGVPMATPVFNGAKEADIETMLEMAGLDRSAQSTLYDGRTGEPFDRKVTMGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYEAIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELTSSKQQQAANDQIEPPADAAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PSAB1_TRIV2
Sequence: MATKFPKFSQDLAQDPTTRRIWYAMAMGNDFESHDGMTEENLYQKIFATHFGHLAIIFLWASSLLFHVAWQGNFEQWIKDPLHVRPIAHAIWDPHFGKPAIEAFTQAGANGPVNIAYSGVYHWWYTIGMRTNTELYTGSVFLLLFASLFLFAGWLHLQPKFRPSLAWFKSAESRLNHHLAGLFGVSSLAWAGHLIHVAIPESRGQHVGWDNFLTTAPHPAGLQPFFTGNWGVYAQNPDTAGHIFSTSQGSGTAILTFLGGFHPQTESLWLTDIAHHHLAIAVLFIVAGHMYRTNFGIGHSIKEMMNAKTFFGKPVEGPFNMPHQGIYDTYNNSLHFQLGWHLACLGVVTSWVAQHMYSLPSYAFIAKDYTTQAALYTHHQYIAIFLMVGAFAHGAIFLVRDYDPEQNKGNVLERVLQHKEAIISHLSWVSLFLGFHTLGLYVHNDVVVAFGTPEKQILIEPVFAQFIQAAHGKVLYGLDTLLSNPDSVAYTAYPNYANVWLPGWLDAINSGTNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYAFPCDGPGRGGTCDISAWDSFYLSLFWALNTVGWVTFYWHWKHLGIWQGNVAQFNENSTYLMGWFRDYLWANSAQLINGYNPYGVNNLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHERTPIANLIRWKDKPVALSIVQARVVGLAHFTVGYVLTYAAFLIASTAGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2 1, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: ENGB_VIBVU
Sequence: MSVKIHYQNTHFITSAPDIRHLPADEGIEIAFAGRSNAGKSSALNRLTNQKNLAKTSKTPGRTQLINLFKVTEGCHIVDLPGYGFAQVPLEMKNKWQKSLGEYLQKRECLKGLVVLMDIRHPMKDLDQQMIFWAIESRIPVQVLLTKADKLKSGARKAELLKVRKLAETFGGDVQVDVYSSLKGLGVDQLRAKLDTWFAPALAHLLEDEEGSNSAE
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: CIPK6_ORYSJ
Sequence: MMAAAAEEGEGKKGGGTVLQGRYEMGRVLGHGNFGRVHVARDLRTGRSVAVKVVAKEKVVRAGMMEQIKREIAVMKRVSHPNIVELHEVMATRSKIYLALELVRGGELFGRIVRLGRVREDAARHYFRQLVSAVDFCHSRGVYHRDLKPENLLLDEAGNLKVVDFGLSALADHARADGLLHTLCGTPGYAAPEVLRDKGYDGAKADLWSCGVILYVLLAGSLPFPDDNIVTLYRKAQRGDYRCPAWLSTDARRLIPRLLDPNPTTRISVAQLVETPWFKKTSISRPVSIELPPAFADPAPAKEEAEKDEPETLNAFHLISLSEGFDLSPLFEGDSAKGRRDGGMLFATREPASGVISRLEGVAARGGGRMRVTKSGARGVRLEGAERGGAKGRLAVAADIFSVAPSVLVVDVKKDGGDTLEYRSFCSEELRPALQDIVWGAAADPTPTAAV
What is the function of this protein?
CIPK serine-threonine protein kinases interact with CBL proteins.  Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).
What are the official names of this protein?
CBL-interacting protein kinase 6, OsCIPK06.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: GLMM_GEOMG
Sequence: MKKLFGTDGVRGVANVYPMTTEMAMQIGRAAAYLFKNGNRRHRIVIGKDTRLSGYMLENALVAGICSMGVDVLVVGPLPTPGIANITSSMRADAGVVISASHNAFQDNGIKFFSRDGFKLPDEMELKIEELIFSKKIDSLRPIATEVGKAYRIDDAVGRYVVFLKNTFPKELDLTGMKIVLDCANGAAYKVAPAVLEELGAEVIPYGIKPNGTNINAGFGSLHPEVISEAVKEHRADLGIALDGDADRVIFVDEFGNEVDGDHIMAICATDMLKHKKLRKNTLVATVMSNMGLDIAVKKAGGKVIKTAVGDRYVVEEMLKGGYNLGGEQSGHMIFLDHNTTGDGMLSALQVLAIMRRSGKTLSELAEVMIPLPQVLVNVRVTEKKDIMTIPEVAALIRGVEDKLKDEGRILIRYSGTEPLLRIMLEGQDKYQITGWAKEIADLVEKKIGGK
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: FMP46_YEAST
Sequence: MSFWKTLQRQPRTISLFTNDIASNIKSQKCLQLLKGDVSHRFDVEIANRFPTWDQLQYMRTSCPQGPVSLQRQIPKLDSVLKYKHTDPTFGMDLQKCVQRGLWNPKEALWVDWENKLVGNEPADIDKYIIQRK
What is the function of this protein?
Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.
What are the official names of this protein?
Putative redox protein FMP46, mitochondrial, Found in mitochondrial proteome protein 46.
What is the protein family that this protein belongs to?
Belongs to the FMP46 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: POL_EIAVY
Sequence: TAWTFLKAMQKCSKKREARGSREAPETNFPDTTEESAQQICCTRDSSDSKSVPRSERNKKGIQCQGEGSSRGSQPGQFVGVTYNLEKRPTTIVLINDTPLNVLLDTGADTSVLTTAHYNRLKYRGRKYQGTGIIGVGGNVETFSTPVTIKKKGRHIKTRMLVADIPVTILGRDILQDLGAKLVLAQLSKEIKFRKIELKEGTMGPKIPQWPLTKEKLEGAKETVQRLLSEGKISEASDNNPYNSPIFVIKKRSGKWRLLQDLRELNKTVQVGTEISRGLPHPGGLIKCKHMTVLDIGDAYFTIPLDPEFRPYTAFTIPSINHQEPDKRYVWKCLPQGFVLSPYIYQKTLQEILQPFRERYPEVQLYQYMDDLFVGSNGSKKQHKELIIELRAILQKGFETPDDKLQEVPPYSWLGYQLCPENWKVQKMQLDMVKNPTLNDVQKLMGNITWMSSGVPGLTVKHIAATTKGCLELNQKVIWTEEAQKELEENNEKIKNAQGLQYYNPEEEMLCEVEITKNYEATYVIKQSQGILWAGKKIMKANKGWSTVKNLMLLLQHVATESITRVGKCPTFKVPFTKEQVMWEMQKGWYYSWLPEIVYTHQVVHDDWRMKLVEEPTSGITIYTDGGKQNGEGIAAYVTSNGRTKQKRLGPVTHQVAERMAIQMALEDTRDKQVNIVTDSYYCWKNITEGLGLEGPQNPWWPIIQNIREKEIVYFAWVPGHKGIYGNQLADEAAKIKEEIMLAYQGTQIKEKRDEDAGFDLCVPYDIMIPVSDTKIIPTDVKIQVPPNSFGWVTGKSSMAKQGLLINGGIIDEGYTGEIQVICTNIGKSNIKLIEGQKFAQLIILQHHSNSRQPWDENKISQRGDKGFGSTGVFWVENIQEAQDEHENWHTSPKILARNYKIPLTVAKQITQECPHCTKQGSGPAGCVMRSPNHWQADCTHLDNKIILHFVESNSGYIHATLLSKENALCTSLAILEWARLFSPKSLHTDNGTNFVAEPVVNLLKFLKIAHTTGIPYHPESQGIVERANRTLKEKIQSHRDNTQTLEAALQLALITCNKGRESMGGQTPWEVFITNQAQVIHEKLLLQQAQSSKKFCFYKIPGEHDWKGPTRVLWKGDGAVVVNDEGKGIIAVPLTRTKLLIKPN
What is the function of this protein?
During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme.  RNase H activity is associated with the reverse transcriptase.
What are the official names of this protein?
Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
Protein: KLH21_HUMAN
Sequence: MERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRFILRHVGELGAEQLERLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWPQLLEAVRLPFVRRFYLLAHVEAEPLVARCPPCLRLLREARDFQAARYDRHDRGPCPRMRPRPSTGLAEILVLVGGCDQDCDELVTVDCYNPQTGQWRYLAEFPDHLGGGYSIVALGNDIYVTGGSDGSRLYDCVWRYNSSVNEWAEVAPMLKAREYHSSSVLDGLLYVVAADSTERYDHTTDSWEALQPMTYPMDNCSTTACRGRLYAIGSLAGKETMVMQCYDPDTDLWSLVDCGQLPPWSFAPKTATLNGLMYFVRDDSAEVDVYNPTRNEWDKIPSMNQVHVGGSLAVLGGKLYVSGGYDNTFELSDVVEAYDPETRAWSVVGRLPEPTFWHGSVSIFRQFMPQTFSGGRGFELDSGSDDMDPGRPRPPRDPDELH
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis.  The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB.  Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
What are the official names of this protein?
Kelch-like protein 21.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle midzone and targets CUL3 to this region.
Protein: LACY_LACHE
Sequence: MHNHKVSGKQIVSYASFCLGNLGHSAFYGVMSTYFIIFITSGMFSGLNQSVADKLIGLITGLMVLVRIIELVIDPILGNVVDNTKTRWGKFKPWILIGTVVSAALLLILFTGIFGLAQQNWILFAILFVLIYIAFDVFYSLSDVSYWGMVPALSEDSHERGIYTSLGAFSGIIGWNSLPIIVVPLVTGVTYAVTGKHEEGAPGWFAFAAVISALAIICALIVCFGTKEKHNIIRDSAKQKTTLRQVFGAIFHNDQILWPSLAYLLYSLAAVITNGVLFYMYKFVIGKPNDFWVVGIIATIIGCCINPSFPVLNKYIPRKWLFIAGQTCMVLAYVLFIFGHNNVFLMDLGLVLFNINFALLVTVLTLTDAIEYGQLKIGQRNEAVVLAVRPMIDKFAGAVSNALVGYVAIAAGMTGSATAADMTSKGINTFNMMALYIPLALAVLSIVVFSLKVTLSEKKHAQVIEELKSKLAQGEIEKKTSVDTGTKEVTIYAPADGELMQMSSVVDEDGKPFPGKGFAIEPSSGQIYAPFDGTIKFTFGTKHAFEIVSQNGLQVVVHVGLGTVNLRGEGFETFYDDGQTVKKGDKLLEFDRDLALNNGYKDTIVIFYTQPGRIQNSGTIQAGKDIKHGEKVVDVQFK
What is the function of this protein?
Responsible for transport of beta-galactosides into the cell, with the concomitant uptake of protons (symport system), and also for transport of homologous and heterologous exchange of beta-galactosides.
What are the official names of this protein?
Lactose permease, Lactose transport protein, Lactose transporter, Lactose-proton symporter.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the sodium:galactoside symporter (TC 2.A.2) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RT17_DICDI
Sequence: MISKIFEIVHKHQKFISGVCISKTHTKTAMCQVKRLYFDKGKYSALNYKTTKYMIHDPNDICAVGDQVHFRECAPVSKRKAHVVEKIVKKNPITEFLRQNPQYIVTPKEIAERKENDKIKYKHITDL
What are the official names of this protein?
Probable 28S ribosomal protein S17, mitochondrial, MRP-S17, S17mt.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YVFA_VACCC
Sequence: MDATAGLHLGFRRLGILTQAASPWNQRSTDVGFGRPPTTYNLLLAGIPVAYSLGLFIGGIGIQLFDI
What are the official names of this protein?
Uncharacterized 7.1 kDa protein.
Protein: TIAS_THEGJ
Sequence: MLLHIGIDDTDSPNGMCTTYLGALLYREISRLAEPTDLPRLIRLNPNIPYKTRGNGAVAMTFEVDEEAVPEVKDLVLFYVNQLADFTHENTNPGVVFFEGEIPEELQEFSLKALREHVTIEEAERVAREVGAEFFKFKLGRGIIGALASIGYPLERFTYELLAYREPENWGTPRKVDAESVFLADRWSYPFTYDNVDPYKRTILIAPHGKDPVLVGLRGIDRGRVLQTFEMVRFGEPVAFYQLYKTNQNTDDHLTPKKIGELKLYDSAVVRGRVSKPYWERGRHVFFELEDETGKIRVAAFEPTKKFRNYVRKLLPGDEIIAAGGVKEHEGVLTLNLEKFYPVKLVPKIEYRKPKCPRCGGTMKSKGDYLKCKRCGYRMPKKLIPVEVPRELERKIYEVPPDARKHLSRPLVLPGGEERVLEALGNSG
What is the function of this protein?
ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
What are the official names of this protein?
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS, tRNA(Ile2)-agm2C synthetase, tRNA(Ile2) agmatidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the TiaS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE1_GRABC
Sequence: MHSLTTHKHVRGGDMTIRTRFAPSPTGLLHVGGARTALFNYLFARHHGGEYLLRIEDTDRARSTPEAVQVILDGLDWLGLSPDQEPVFQSTRETRHTEVAHSLLERGMAYRCFLSPEELQAQRDQAAADKRPLRINSPWRDRDLSEAPSGIAPVIRLRVPQEGETVVDDLVQGPVRVANAELDDMIILRSDGTPTYLHAVVVDDHDMAITHVIRGDDHLTNTFRQVQIFKALGWDLPRFAHIPLIHGADGAKLSKRHGAVSVLEFEREGFLPEALCNYLLRLGWGHGDAEILSRDEQVALFDLDGVGRAASRMDYAKLTHLNGVYLREADDQRLTTDLCRRLDLSPDSDASSRIRRLMPKLKERARTLVDLAESARFVIERPSGPKDAKAAALLSDEARGWLRALLPQLQATDFSAAAVDQALRAFAEEHGLKLGQIAQPLRVALTGGTTSPPIDATLEALGASEVTSRIEAV
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_LEGPA
Sequence: MNDLKKSPLLILDFGSQYTQLIARRVREMGVYCEIYPYNINHEQFKKLNPCGVILSGGPSTVTHDANPRAPQWLFESDLPLLGICYGMQTMAVQLGGQVHSSTLREFGYAELRLHGHSQLLSNIEDRTAMDGSALLDVWMSHGDKVTELPPGFKVICETRNAPIAGMADESRQMYGLQFHPEVTHTLQGLRILQRFVVDICKASTDWTPEHIIDEAINKIREQVGTEKVLLGLSGGVDSSVVAALLHRAIGEQLVCVFVDTGLLRLNEAEQVLSMFGRHMGIRIIAVNAEDKFLTALKGVTCPEEKRKIIGRTFIEVFDEEAQKLTDIKWLAQGTIYPDVIESAATSTNDAAVVIKSHHNVGGLPDTLNLKLLEPIRELFKDEVRHVGLELGLPHDMVYRHPFPGPGLGVRILAEVKKEYADILRKADAIFIEELHNAQLYHKISQAFAVFLPVKSVGVMGDGRRYDYVICLRAVETVDFMTAHWSQLPWDFLGKVSNRIINEVEGVSRVTYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL34_THEOS
Sequence: MKRTWQPNRRKRAKTHGFRARMRTPGGRKVLKRRRQKGRWRLTPRVHR
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL7_STRS7
Sequence: MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAAGGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAAEAEEIKAKLEEAGATITLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RS15_CAMJ8
Sequence: MALDSAKKAEIVAKFAKKPGDTGSTEVQVALLTARIAELTEHLKIYKKDFSSRLGLLKLVGQRKRLLSYLKRKDYNSYSKLITELNLRDK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: GCSP_SHIB3
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNSNRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLEIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNSAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETSISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: SYG_DEIGD
Sequence: MPATSMEELVSLCKRRGFIFQGSEIYGGLQGFWDYGPLGVELKNNIKASWWRANVYERDDMEGLDAAIIMHRLVLRHSGHEATFSDPMVDNRKTKKRYRLDHLVKDQKPDVVAQVAEGIGESVENFAAVVAALVAHPAKAAEVLVAAGVRDPFSGEVGDWTEPRPFNMMFKTSIGPVADEDSFGYLRPETAQGIFTNFKNVVDSTSRRLPFGIAQIGKAFRNEITPRNFIFRVRELEQMEIEFFCTPGTDEAWHQHWLEARLAWWEAQGIPREKIQILDVPKEDLAHYSKRTYDLMYNYPTLGYEEIEGIANRTDFDLGSHTKAQAELGIQARVEENFDSVAKLTIPHPETNKPVVPFVIEPSAGVDRAMLAVLAEAYTKETLENGSERIVLKLKPHLAPIKVAVIPLARNREEITSVAKAIKAKLQSLGLGRVLYEDSGNIGKAYRRHDEVGTPYCVTVDFETVGKGEDPALTDTVTVRDRDTLGQERVRISELANWLQARLR
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG5_HUMAN
Sequence: MTDDKDVLRDVWFGRIPTCFTLYQDEITEREAEPYYLLLPRVSYLTLVTDKVKKHFQKVMRQEDISEIWFEYEGTPLKWHYPIGLLFDLLASSSALPWNITVHFKSFPEKDLLHCPSKDAIEAHFMSCMKEADALKHKSQVINEMQKKDHKQLWMGLQNDRFDQFWAINRKLMEYPAEENGFRYIPFRIYQTTTERPFIQKLFRPVAADGQLHTLGDLLKEVCPSAIDPEDGEKKNQVMIHGIEPMLETPLQWLSEHLSYPDNFLHISIIPQPTD
What is the function of this protein?
(Microbial infection) May act as a proviral factor.  In association with ATG12, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection (PubMed:17709747).  Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for initiation of HCV replication, but not required once infection is established (PubMed:19666601).
What are the official names of this protein?
Autophagy protein 5, APG5-like, Apoptosis-specific protein.
What is the protein family that this protein belongs to?
Belongs to the ATG5 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=Colocalizes with nonmuscle actin. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed (By similarity). Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme.
Protein: SYI_PYRAB
Sequence: MIKEPEFREYDPKKLEEKVEKFWSENEIYRKVKELRKDGPKYYFLDGPPYVSGAIHLGTAWNKIIKDMIIRFRTMQGYNVWRQPGYDMHGLPIEVKVEQALGLKTKKEIEEKIGVENFIKKCKEFALNNLKIMTEQFKMLGIWMDWDNPYMTIKNEYIESAWFTLKRAWEKGLLEKDKRVLHWCPRCETALAEHEVRGEYKLRKDPSIYVKFPVEGKENEYLLIWTTTPWTLPANLAVSAHPDYDYVKVKVEFNGREEYWILAKALVDKVLGEIGVKGEVVEEFKGRELEGLRYVHILMDEYPRQKEFKEKYEWAHRVILADFVTLEEGTGLVHTAPGHGEEDFEVGQKYGLPVYSPLDDQGKYTEGKWKGIYVKEADPKIIEHLREKGYLVKAGEIEHKYPHCWRCKTPLIFRATDQWFLKISKVKDKIIKENDEKVTWYPDWVKIRFDNGVRDSGDWVISRQRYWGIPLPIWQSEDGEIYVVGSWRELVELAVAIEVNGERIELPESYEEKLKVIEEKLGPEDLHRPYVDAFIIKVNGKDMRRVKDVVDVWFDSGIASWASLGYPRNKELFEKLWPADFIVEGEDQVTKWFYSQQAASIVAFDTVPYRRVAMHGYVLDEKGDKMSKSLGNIIRPEEVVERAGRDTFRFYMLWATNPWENLKFSWKGVEQVRRMLNILWNVYVLASTYMSLDNFDPRKLNPDELPFREEDKWILSRVNSLISEVENGIESFYLTKATRALYNFVVEDLSRWYVRLIRKRLWVEGEDPDKLAAYYTLWKVFDVLLRLLAPFTPYIAEEIYQNLIRPFTNVESVHMLDWPKVDEKAIDEELEREMEFIRRIVEAGSAARQRAKIKLRYPVRRIIIETEDETVKKAVERLNRILRDQLNAKEVKVGRVERELTIKPNFAKLGPEFKGDAKIIAKWINENGRELYEKGELTVEIDGKTFHLTREHIIVEEKLPDFFVSEEFEGGRVFVDKTLTRELIAEGLAREFVRRIQEMRKRLDLDVNDRIIVTIETTDENVELLKENLDYIMRETRADKIVFGKAKGYVVEWPEVQAKIGIEKVEE
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK2_VITVI
Sequence: MAIHLYKTSTPSTRNRAVDSQVKSNPRNNLIYGQHRCGKGRNARGIITAGHRGGGHKRLYRKIDFRRNEKDIYGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPIKMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDNLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS16_CHLL3
Sequence: MVKIRLRRAGRKKLPVYQIVAADARAPRDGKFLEVVGHYQPTAKPHVVTLDRERVAYWMQTGAQPTSTVRSLIQKTGLLYELRLKKLGRSEAEVAEEMEKWQEKQAERRQKRLNVKSRRRQLKKEAAAKPAVAEEVAAPVAAAPVAEAPVAEVEVVIAPEVQVEAAVEAVPEAPVAAAEPAPEVKAEEKEEGGEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: EFTS_ACTP7
Sequence: MAEITASLVKELRERTGAGMMECKKALVEANGDIELAIDNMRKSGQAKAAKKAGRVAAEGVILARIGAGFGVLVEMNCETDFVAKDAGFLGLANEVADFALANKGTTIETLAAQFEEKRAALVAKIGENMNIRRVQYLDGQVIAQYLHGAKIGVLVAGEGSDEELKKVAMHVAASRPEFVNPEDVSAEVVAHERQIQIDIAINSGKPKEIAEKMVEGRMKKFTGEVSLTGQAFVMDPSQSVGDYLKSVNTKVTNFIRLEVGEGIEKVEEDFAAEVAKITGGNA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_SALA4
Sequence: MSFIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAFTLREAQGDIPAVVMHYGVFIQNVFDFVIVAFAIFVAIKLINRLNRKKAEEPAAPPAPSKEEVLLGEIRDLLKEQNNRS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: U1_SCSVF
Sequence: MVSFSFPEIYDVSDDVLVSDSRRSVAVEVEEKVQVINVKVLRLIEAVDEDRVGVKVMFRLCYRYRRELKITLLGCKMELWTSLKSSGKYSVQSLLQRKLNGICVSNYCIGIDMFVSNVKELINRCKWITSVQGVNPICCLYHMDEE
What are the official names of this protein?
Protein U1.
What is the protein family that this protein belongs to?
Belongs to the nanovirus U1 protein family.
Protein: SYGA_ECOHS
Sequence: MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVTGEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.