PharMolix/UniProtQA huggingface dataset:
Protein: ISPG_LEPIN
Sequence: MNFRYNQTPFGYQRRKTREVKVGDVKVGGNNPIVIQSMINSDTTDTQGSVKQILELERAGCEIVRLTVPSQADADNLPSIRQELKKAGSKVPLVADIHFTPSVAMKAVEYVEKVRINPGNFADKKKFAVRDYTDLEYNQELERISEVFSPLVLRCKELGVSMRIGTNHGSLSDRIMNRYGDTPQGMVESALEFIRIAESLGYYDIIVSMKASNPQVMVQAYRMLASRFNELKMDYPLHLGVTEAGDGNDGRIKSAIGIGSLLEDGLGDTIRVSLTEDPVLEVPVAKLLADKFNKKISNLNSVKGYSEFRNPFSYNRFYSSEIKIVQFEAGENHPVRVETILPFENSNSFLENVAKLYQYGKSLSIEPESILVDSPLPDQLKEISEAATALSIPVGILLSKNVSLNEKLQKELLSFPKIVFDPFLQFQDGEKMLSFLKERQNAGLFSEIHTSGDKLDSLRGLPDTLSEIGIKNVLFSLDSKEILYDYRKLGSILSRFEFPILLHGSFSNPEEALYNSAIGIGGLLIDGIGDLIRISTSKIKDIEEIFQLSYDLLQGTRLRLTKTEYISCPSCGRTLFDLQETTARIKSRTGHLKGVKIAVMGCIVNGPGEMADADFGYVGAGPGKVHLYRGKEIVLKNVPSEIADEKLVQLIKDNGLWQDPSND
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: RS9_GEODF
Sequence: MAAASFYGTGKRKSSIARVWLKPGTGVITVNHKTLDEYFGRETSKMVVKQPLELTENLGKFDIYVTVSGGGDSGQAGAIKHGITKALLEVDAALRTPLKKAGFVTRDSRIKERKKYGKKSARASFQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: MATK_WELMI
Sequence: MGNFYRKNIEILGQQRFLYPLLFQDEFYAIAQNLFSNPRASVEVREEICKNCNSFSFFTVKRLIFKIRKRNVFLESKNKNSISLALIAEGLTLGLDVFFSAQWKRFVDGEGGTEQLSFQSIHSIFAYLDETTPYSFSSLGIRIPSYVHPELFIRMFNCLCWIDDVCFLHLLSSMLCFLKHLTILDKFIFFNSKGFIRLVLFLWNIFVSKGESSKISLWKQKCYRAKFKSFGSFAEQTHFHRKMKLKNPKIKAHEKFSEVFFFSHYSRFGEKSVLIGTPILIKKYRYFFCHFWQTSFFFSETYGLFVHEFSRKNISLIGYSFYFQNHRTFFRIKMFYDFFFTELVNNEFHPKFGIISIMKFLSIEGFCDIMGRPISKLSWTCFTDDDIFDKCDRFWKILYYYYCGAKNKAYLDRIKYILLLSCFKTIAFKHKSTIRVVRKEFDFELRKKFFPKEIEFERDFLCSRFAQKFKKWLLKINLATERFWLLNILKVHFLTKSWHKDQDALDFCLIVEKNNILPMLNNFL
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y135_MYCPN
Sequence: MFKWLLKHRSKPTPLELGIFDQKVSFWKPFLLFCPALLTTFLFTLVPFFLTLQKGFSHNEDIYRVDSQQFGFQTFANLFSESNFILGLRNSFLYSIISLPLTIVLAIIISSAIVFVYRKLARGFWQTVFFLPYVTSGVAVSIAFIYILDSSSGILNNIFHVNIKWLDSGERDTFNALWGILIFGIWKNMAFNVLVISTAMLSVDPTLYKVANLDGAKPIRQFFKITLPSIRPTLIFLLTLLILGGMQVFPISLFNGNDSEAVTNGGSTILLYIFQKIRDQNNNFAGAATLVLFILGVCYGLVLRNGFRLIEWAQWKIKRHYVQTKLNLV
What is the function of this protein?
Probably part of a binding-protein-dependent transport system.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein MG188 homolog.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4LM_DUGDU
Sequence: MPFIYINILLAFFISFIGLLMYRSHLMSSLLCLEGMMLSLYILGTLLCLNMHFTLSAMIPMILLVFAACEAAVGLALLVMVSNTYGLDHVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RHAM_ESCF3
Sequence: MIRKAFVMQVNPDAHEEYQHRHNPIWPELEVVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANPNNSPVSSELQEVFYLP
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_COLP3
Sequence: MKDDKEKALSAALAQIERQFGKGSIMKLGDNTTMDVETISTGSLGLDIALGAGGLPMGRVVEIYGPESSGKTTLTLEVIAEAQRNGKVCAFIDAEHALDPVYAEKLGVNIDELLISQPDTGEQALEIVDMLTRSGAIDVIVVDSVAALTPKAEIEGDMGDSHMGLQARMLSQAMRKLTGNLKKSNTMLIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGAVKNGDEIVGNETRVKVVKNKIAPPFKQAEFQILYGEGINNLGELIELGVKHEFVEKAGAWYSCNGERIGQGKANAAKYLDEHPEMAKDVDTKLRDMFLSKTVVAEDKSEVKEKEKA
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BORAP
Sequence: MLKAVLERTIGSKSKRDLKDYLPTLRNINKLERWALLLSDEDFSKETEKLKDELKSGNSLESILERAFTLSREAARRRLKERPYDVQIIAGLALHKGKIIEMKTGEGKTLSSVQAAYLNSLTGDGVIIVTVNDYLAERDSNWMKPVFDLLGVSVGVVLSNMDYELRKAQYAKDITYVTNNELGFDYLRDNMRYDLNEKSLRKFNYCIIDEIDSILIDEARTPLIISGPTEGNTNAYLEVNSLVSFLKECSKDSKTGDYPLEIDDLDGDYTVDEKAKRISFTAKGLNNLEQLLVSKGIISGSMYTDSNFNYVHYMTQALKAHLLFLKNREYIVGDSGVEIVDEFTGRVLTGRRYSDGLHQAIEAKEGVRVANENKTMATITFQNLFRMFNKISGMTGTADTEAKEFHRIYNLDVVVVPTNRLLARIDEDDTIYYTEEFKFNAITDEVYKTYKKGQPVLVGTVSIEKSEILSAMFKSRGIKHEVLNAKNHSREAFIIAEAGAKHAVTIATNMAGRGTDIKLGGNIEHRVRKKIGTNVSLEEFQEAVKNEREDYLKDYNEVKSLGGLYVIGSERHESRRIDNQLRGRSGRQGDPGRSRFYVSLEDDLMRLFAGDNLRSLMGKLGMATGEPITHSLLTKSLINAQKRVEDRNFEIRKHLLEYDDVITKQRDFIYAQRNSILEDTAIKDRILIALEEYLTFLLEGAKSSTVSNVFLNEVNLIFAYMLEGLGSIENINSLDLKAKLMQIAKANLDEKENSIGRDLFNGFLRYEYLRNIDSKFQEHLANLDSLREAVYLRSYANKNPITEYKEEGFLIFSELIKDIKVSTIRRVLQLKLDSNSSNFKSVKKSKNVNSIHKELSGIVINENKSVSNVQVVRSSPKIGRNEPCYCGSGKKYKNCHGKS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: PDRP_RHIME
Sequence: MENRKNYFHLHLISDSTGETLIAAGRAAAAQFQSSHALEHVYPLIRNRKQLMQVMDAVDGAPGIVLYTIVDRELAGLIDQRCREIGVPCVSVLDPIIELFQSYLGSPSRRRSGAQHVMDAEYFARIEALNFTMDHDDGQVPSDFNEADVVLVGVSRTSKTPTSIYLANRGIKTANIPIVPGVPLPDALLKATKPLIVGLIASAERLSQVRQHRVLGTTQSFHGEDYTDRAAIAEELKYARSLCARNNWPLIDVTRRSIEETAAAIVALRPRLR
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: GLRX1_RHIID
Sequence: MSQIKDRVEKLIQTNPVMMFSKSFCPYCKKAKATLKELNVEPGICELDEDSEGRAIQDYLKEKTSQNTVPNIFIKGQHVGGCDDLLAAKDNGSLSKMIAAL
What is the function of this protein?
Multifunctional enzyme with glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity.  The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.  In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase.  May play a role in protection against oxidative stress caused by superoxide in vivo by regulating the redox state of the protein sulfhydryl groups.
What are the official names of this protein?
Glutaredoxin-1, Glutathione-dependent oxidoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y281_PECAS
Sequence: MKQKPEDWLNDVPDNQEDDEDDEIIWVSKSEIKRDAEALKDLGAELVDLGKNALEKIPLDDDLRAAVELAQRITREGRRRQLQLIGKLLRARDPEPIQIALDKLNNRHNQQVALFHKLEQLRDRLITEGDDVIPEILALYSHADRQQLRSLVRNAQKEKAANKPPKAARQIFQYLRELAETTN
What are the official names of this protein?
UPF0307 protein ECA0281.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: CISD2_BOVIN
Sequence: MVLESVARIVKVQLPAYLKRLPVPESITGFARLTVSEWLRLLPFLGVLALLGYLAVRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLCLTKAAYCRCWRSKTFPACDGSHNKHNELTGDNVGPLILKKKEV
What is the function of this protein?
Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum.  Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy.  Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases.  Involved in life span control, probably via its function as regulator of autophagy (By similarity).
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein.
Protein: KITH_RACVI
Sequence: MNGGHIQLIIGPMFSGKSTELIRRVRRYQIAQYKCITIKYTNDTRYGTGLWTHDKHNFSAMETTKLLNIIDAVTDFSVIGIDEGQFFPDIVEFCEYMANNGKIVIVAALDGTFQRKPFTTISNLIPLSEMVVKLTAVCMKCFKEASFSKRLGTETEIEIIGGEDMYQSVCRKCYINE
What is the function of this protein?
Phosphorylates thymidine and thymidine analogs, such as azidothymidine (AZT).  Part of the salvage pathway for pyrimidine deoxyribonucleotide synthesis.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
Protein: HIS3_NITMU
Sequence: MSDTWLNKVNWSADGLVPVVTQDAISNKVLMVAWMNPEALRLTAQTGEAHYWSRSRKKLWHKGEESGHVQKVKEIRLDCDEDVLLLVVEQVGGVACHTGRHHCFFKKLEQDQWLVTEPVIKNPEEIYGQR
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHLP1_PLABA
Sequence: MIFKKALYILLFLYIAIVKKGESKPGSKHPFLFKNLVIDKKKLDSSYYNKYDNIKWNGKIIAIGDIHGDIESLKLILRHSKLIGENDNWIGDNVLLVQNGDVFDRGIYGPIIYNFLFKLQKEAIKKNSRVILIMGNHEQLNLCGYFNYVNPKEIEMFFHNDANYRYHSFVNPYGEYHKRLIRLPPMVKVNNIIFTHGGLNLLISKLSINDINLKTRLQIENNCKPIKYDSFQNYLSRDGVLWSDAMSRNVPYYEKEKCSELFQILDKYDAKYLVVGHTRQPSHQIGSYCNNHYFLIDTGMSLFTNYGQPYPNYLKIDDHKIKAVRLIVEKKKKCPHTEIQLNTPNKIKYCVQESQTNLNPVL
What is the function of this protein?
Phosphatase which plays an essential role in the development and differentiation of the ookinete and in the formation of ookinete micronemes.
What are the official names of this protein?
Shewanella-like protein phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. SLP family.
Protein: YHY4_SCHPO
Sequence: MTEVTKINPSTAITELEPYEMAQTNKEVPTTSLLSKDYYGHSIEEPDENNPTRWRYERPLDTVRAWQYLIDCDENFKTKPHREQNQYRPTADSFRPLSFASMESKLTQRLSRHLSKTSSRHSRL
What are the official names of this protein?
Uncharacterized protein C19C7.04c.
Protein: TRUB_PROMM
Sequence: MTVPFGFVVIDKPAGITSHDCVSRMRRVFGIKRVGHGGTLDPAVTGVLPIALGHATRLLPYLPGAKSYRGSIQLGQRTSSDDQQGDLISKQAWPELNTAEIEAYLEPFRGRIQQRPPQVSAVHVQGERAHARARRGETMEIPARTITIDRLQLLNWNQQLGQIDFNVHCSSGTYIRSLARDLGELIGCGACLGWLKRTQALGFHEQQAVPLPDRDNPALTTPPAVLPPLTALAHLPRLQLNEEEQESWSCGRRITAHQDQCQPAPKPLASDQQESAPNQTDPSANKSMLVVIDCRGEVAGMAYWEDNATVKPKVVFNAQG
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SEPS_METBU
Sequence: MKFDPESIKKAAKEDFDSAWTSGKDLIKKTGLNQQYPHTSFHFGKAHPVYDTIAKLREAYLRMGFDEMMNPLIVDEKEVYKQFGHEALAVLDRCYYLAGLPRPNVGISDQRIAKIKEMLGGIDDEGIETIRKVLHSYKKGEVEGDDLVPEIALKLNVSDALVVEMIDKVFPEFKELTPQATTKTLRSHMTSGWFISLSGILERSRPPFHLFSIDRSFRREQQEDASRLMTYYSASCVIMDEDVTVDHGKAVAQGLLAQFGFEKFMFRPDEKRSKYYVPDTQIEVFAYHPKLVGSNTKYSDGWIEIATFGIYSPTALAEYNIPCPVMNLGLGVERLAMILHDSTDLRGMTYPQLPQYAEWELKDNELARMIFVDKLPETPEGQEILEGIVMQCDMHGSEPSPCEFVAWEGILKGKKVKVSVIEPEEDTKLCGPAAYNEVLVHENDVLGLPNNKKWKKAFENHSARTGVRFIEAFAAQAAKEIEEAVEKGEKECETRVRIVKVPSEINIKLDPLAQRYITGKKQKIDIRGPVFTTVRAEIE
What is the function of this protein?
Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys).
What are the official names of this protein?
O-phosphoserine--tRNA(Cys) ligase, O-phosphoserine--tRNA ligase, Non-canonical O-phosphoseryl-tRNA(Cys) synthetase, O-phosphoseryl-tRNA(Cys) synthetase, SepRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. O-phosphoseryl-tRNA(Cys) synthetase subfamily.
Protein: VGLL4_HUMAN
Sequence: METPLDVLSRAASLVHADDEKREAALRGEPRMQTLPVASALSSHRTGPPPISPSKRKFSMEPGDEDLDCDNDHVSKMSRIFNPHLNKTANGDCRRDPRERSRSPIERAVAPTMSLHGSHLYTSLPSLGLEQPLALTKNSLDASRPAGLSPTLTPGERQQNRPSVITCASAGARNCNLSHCPIAHSGCAAPGPASYRRPPSAATTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS
What is the function of this protein?
May act as a specific coactivator for the mammalian TEFs.
What are the official names of this protein?
Transcription cofactor vestigial-like protein 4, Vgl-4.
What is the protein family that this protein belongs to?
Belongs to the vestigial family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TFB2_DEBHA
Sequence: MSSSNLFKATVNEHLEGLPKQVQSRLYEAPATCLSIYRLLPPIAKFYIMTMLFYETPVALKDLDKWCKPTSRKFQFDSLKRLRALHLIEEDSSGSHIRLHPTFRQNFRDCLTGSQARNAFGNLSTTPDEQSVSIKFLDSFALQKWESILHFMVGTELSVTPSNSVLSLLKSGGLMEGTNKGGNRLNITNSGFQFLLQDINAQIWTLLLQYLNLTQDLNMDPVDVLNFIFILGSLELGKGYTVSSLSETQISMLADLRDYGLIYQRSENSERFYPTRLATTLTSDSAALKSPSMAMEQALESTTETEEQQNLASNSNQGTIILETNFKIYAYTNSPLEIAILNLFVHLKTRFSNMVCGQITRESIRNALYNGITADQIIKFLETHAHSQMKILAKERLDKKIEFDTSNNINTAGGAPQSQMMTNENGTTVAQHKLEVLPPTVVDQIKLWQLELDRIQTFEGYLFKDFASQQEFEALSNYASEIGVLLWSNKSKMKFFVTKDGISQVADFASRNQRR
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
What are the official names of this protein?
General transcription and DNA repair factor IIH subunit TFB2, TFIIH subunit TFB2, RNA polymerase II transcription factor B subunit 2.
What is the protein family that this protein belongs to?
Belongs to the TFB2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BUTA_STAAS
Sequence: MTNNKVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSNRDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITEEQFKTVYGVNVAGVLWGIQAAHEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFAPGIVQTPMMESIAVATAEEAGKPEAWGWEQFTSQIALGRVSQPEDVSNVVSFLAGKDSDYITGQTIIVDGGMRFR
What is the function of this protein?
Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.
What are the official names of this protein?
Diacetyl reductase [(S)-acetoin forming], Acetoin(diacetyl) reductase, AR, Meso-2,3-butanediol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: CUX1_CONCL
Sequence: DNSCTPKPSCFF
What are the official names of this protein?
Conotoxin Cltx-1, CalTx-1.
What are the subcellular locations of this protein?
Secreted.
Protein: LIVB8_BRUA2
Sequence: MRLSRLLIGASLGVALSSTVFTAALADVKFGSLYPISGSLALLGEESARGLELAVDEVNAAGGIKGEKVVLERGDAVDNNQATGEARRLISLVGVKAIFGTYSSARVIAASQVSELAGIPYFEMGAVADEVTGRGLQYLFRTNPTAENMAKDSVDMLIKGIAPGLGKDPKDMKIGIIYEDSSYGTSVAGHQEDNAKAAGLTVVLKSGYPSNTVDMSSLVLELREKGADVVMQTSYQNDSVLFLQQANEAGYKPLAIIGGGGGYSMQPTADAVGHDLIDGVFDADYTQYAVNTSATPGLTEFVEAYKAKYGSQPRSGHSLTNYVGAKAIFQALNAGEGFEPDQIVSAVKALDIPDGQTAAGYGVKFGKNNQNERATMMGMQWQDGKLVTVYPENAAIAKMRFKK
What is the function of this protein?
Component of an amino-acid transport system.
What are the official names of this protein?
Leu/Ile/Val-binding protein homolog 8.
What is the protein family that this protein belongs to?
Belongs to the leucine-binding protein family.
Protein: UP15_PSEMZ
Sequence: VGQDATISFK
What are the official names of this protein?
Unknown protein 15.
Protein: VP3_ROTAD
Sequence: MKVLALRHSVAQVYADTQTYLHDDSKDEYENAFLISNLTTHNILYLNYSLKTLKILNKSGIAAVEVQSPDELFALIRCNFTYDYENNIVYLHDYSYYTNNEIRTDQHWITKTDIIDYLLPGWKLTYVGYNGKNTRGHYNFSFICQNAATDDDIIIEYIYSNELDFQNFLLRKIKERMTTSLPIARLSNRVFRDKLFPSIVNIHKKVINVGPRNESMFTFLNFPTIKQFSNGAYIVKHTIKLKQEKWLGKRVSQFDIGQYKNMLNVVTTIYYYYNLYYSKPIIYMLGSAPSYWIYDIKQYSDFTFETWDPLDTPYSTTHHKELFFDKDVNKLKDNSVLYIDIRTDRGNMDWKEWRKIVEQQTVSNLNIAYKYLSTGKAKVCCVKLTAMDLELPITAKLLHHPTTEVRSEFYAILDVWDIITIKRFIPKGVFYAFINNVTTENVFIQPPFKLKTSPTDYIVALYALSNDFNSRQDVINLINKQKQSLITVRINNTFKDEPKVNFKNIYDWTFLPTDFELKDSIITSYDGCLGIFGLSISLSSKPTGNNHLFIINGTDKYDKLDQYANHMGISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYAFDLKRWIYLHSIGKVAVEGGRYYEHAPIELIYACRSAKEFAILQDDLTVLRYANEIEGYINKVYSITYADDPNYFIGIKFNSIPYEYDVKIPHLTLGVLFISDNMIHDVITALKKMKTELFKMEISTSYTYMLSDNTYVANASGVLSTYFKLYNMFYRNHITFGQSRMFIPHITLSFSNKRTVRIESIKLRINSIYLRKIKGETVFDMSE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: FDHD_STAA1
Sequence: MNKDVSLGQPIVRYEDGKLFNTTDQYVTEFPLTIMVNGEEFATVICSPTNLEELVIGFLASEGAILKRDELKSVLIDDSKGFAHVELNKDLGDRFQYSTKRMIASCCGKSREFYFQNDAAIAKTSMSKITLTPIQIINMMTRLQSASHIYQETGGLHNAAISDGLTFFVHRQDIGRHNALDKLYGFCIQRHITVRDKVLIFSGRISSEILIKAAKIGVGVILSKSAPTTLAVTLANDLNITAVGFIRNGGFNIYSHPERIIDSEQ
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2012_MYCTO
Sequence: MLSKSKRSCRRRETLRIGEKMSAPITNLQAAQRDAIMNRPAVNGFPHLAETLRRAGVRTNTWWLPAMQSLYETDYGPVLDQGVPLIDGVAEVPAFDRTALVTALRADQAGQTSFREFAAAAWRAGVLRYVVDLENRTCTYFGLHDQTYMEHYAAVEPSGGAPTS
What are the official names of this protein?
Uncharacterized protein MT2067.
Protein: SYD_SHISS
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMIFFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANPTVLAELSIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPCAM_BOVIN
Sequence: MAPPQVLAFGLLVAAATAAVAADQEGCVCENYKLTTNCSVNALGQCQCTSVGTQHSVICTKLATKCLVMKAEMNHSKSGRRGKPEGAIQNNDGLYDPECDDKGLFKAKQCNGTSTCWCVNTAGVRRTDKDSEISCSEPVRTYWIIIELKHKTREKPYDLQSLQSALKDVITNRYQLDPKYITNILYENDVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKDESLFHSKRMDLRVNGELLDLDPGRTSIYYVDEKPPEFSMQGLQAGIIAVIVVVVVAIIAGIIVLVVSRKKSMTKYEKAEIKEMGEMHRELNA
What is the function of this protein?
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection.  Plays a role in embryonic stem cells proliferation and differentiation.  Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity).
What are the official names of this protein?
Epithelial cell adhesion molecule, Ep-CAM, Tumor-associated calcium signal transducer 1.
What is the protein family that this protein belongs to?
Belongs to the EPCAM family.
What are the subcellular locations of this protein?
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Protein: BAG4_HUMAN
Sequence: MSALRRSGYGPSDGPSYGRYYGPGGGDVPVHPPPPLYPLRPEPPQPPISWRVRGGGPAETTWLGEGGGGDGYYPSGGAWPEPGRAGGSHQEQPPYPSYNSNYWNSTARSRAPYPSTYPVRPELQGQSLNSYTNGAYGPTYPPGPGANTASYSGAYYAPGYTQTSYSTEVPSTYRSSGNSPTPVSRWIYPQQDCQTEAPPLRGQVPGYPPSQNPGMTLPHYPYGDGNRSVPQSGPTVRPQEDAWASPGAYGMGGRYPWPSSAPSAPPGNLYMTESTSPWPSSGSPQSPPSPPVQQPKDSSYPYSQSDQSMNRHNFPCSVHQYESSGTVNNDDSDLLDSQVQYSAEPQLYGNATSDHPNNQDQSSSLPEECVPSDESTPPSIKKIIHVLEKVQYLEQEVEEFVGKKTDKAYWLLEEMLTKELLELDSVETGGQDSVRQARKEAVCKIQAILEKLEKKGL
What is the function of this protein?
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity).  Prevents constitutive TNFRSF1A signaling.  Negative regulator of PRKN translocation to damaged mitochondria.
What are the official names of this protein?
BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, Silencer of death domains.
What are the subcellular locations of this protein?
Cytoplasm.