PharMolix/UniProtQA huggingface dataset:
Protein: ACPS_SALHS
Sequence: MAILGLGTDIVEIARIEAVISRSGERLARRVLSDNEWAIWETHQQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALTLAEKLGVAHMHVTLADERHYACATVILES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UB2G1_HUMAN
Sequence: MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination.  May be involved in degradation of muscle-specific proteins.  Mediates polyubiquitination of CYP3A4.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 G1, E2 ubiquitin-conjugating enzyme G1, E217K, UBC7, Ubiquitin carrier protein G1, Ubiquitin-protein ligase G1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RL29_ACIAD
Sequence: MKTIDLREKSVEELKALLDEQQLNQFRLRMAKATGQLGKSHEVQIARKTIARIKTLLTEKQGNGQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: CASP4_HUMAN
Sequence: MAEGNHRKKPLKVLESLGKDFLTGVLDNLVEQNVLNWKEEEKKKYYDAKTEDKVRVMADSMQEKQRMAGQMLLQTFFNIDQISPNKKAHPNMEAGPPESGESTDALKLCPHEEFLRLCKERAEEIYPIKERNNRTRLALIICNTEFDHLPPRNGADFDITGMKELLEGLDYSVDVEENLTARDMESALRAFATRPEHKSSDSTFLVLMSHGILEGICGTVHDEKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGANRGELWVRDSPASLEVASSQSSENLEEDAVYKTHVEKDFIAFCSSTPHNVSWRDSTMGSIFITQLITCFQKYSWCCHLEEVFRKVQQSFETPRAKAQMPTIERLSMTRYFYLFPGN
What is the function of this protein?
(Microbial infection) In response to the Td92 surface protein of the periodontal pathogen T. denticola, activated by cathepsin CTSG which leads to production and secretion of IL1A and pyroptosis of gingival fibroblasts.
What are the official names of this protein?
Caspase-4, CASP-4, ICE and Ced-3 homolog 2, ICH-2, ICE(rel)-II, Mih1, Protease TX.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14A family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion. Inflammasome. Secreted. Note=Predominantly localizes to the endoplasmic reticulum (ER). Association with the ER membrane requires TMEM214 (PubMed:15123740). Released in the extracellular milieu by keratinocytes following UVB irradiation (PubMed:22246630).
Protein: FPG_ECO7I
Sequence: MPELPEVETSRRGIEPYLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: IGA2_HAEIF
Sequence: MLNKKFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGRFSVGATNVEVRDKNNHSLGNVLPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNDKSHRDVSSEENRYFSVEKNEYPTKLNGKAVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYKVNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGYNKKSWQEWNIYKPEFAKTVLDKDTAGSLTGSNTQYNWNPTGKTSVISNGSESLNVDLFDSSQDTDSKKNNHGKSVTLRGSGTLTLNNNIDQGAGGLFFEGDYEVKGTSDSTTWKGAGVSVADGKTVTWKVHNPKSDRLAKIGKGTLIVEGKGENKGSLKVGDGTVILKQQADANNKVKAFSQVGIVSGRSTVVLNDDKQVDPNSIYFGFRGGRLDANGNNLTFEHIRNIDDGARLVNHNTSKTSTVTITGESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLYLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNGDLKVEKGTLFLSGRPTPHARDIAGISSTKKDQHFAENNEVVVEDDWINRNFKATNINVTNNATLYSGRNVANITSNITASDNAKVHIGYKAGDTVCVRSDYTGYVTCTTDKLSDKALNSFNATNVSGNVNLSGNANFVLGKANLFGTISGTGNSQVRLTENSHWHLTGDSNVNQLNLDKGHIHLNAQNDANKVTTYNTLTVNSLSGNGSFYYLTDLSNKQGDKVVVTKSATGNFTLQVADKTGEPTKNELTLFDASNATRNNLNVSLVGNTVDLGAWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVETPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNGEVAEEAKPSVKANTQTNEVAQSGSETEETQTTEIKETAKVEKEEKAKVEKEEKAKVEKDEIQEAPQMASETSPKQAKPAPKEVSTDTKVEETQVQAQPQTQSTTVAAAEATSPNSKPAEETQPSEKTNAEPVTPVVSKNQTENTTDQPTEREKTAKVETEKTQEPPQVASQASPKQEQSETVQPQAVLESENVPTVNNAEEVQAQLQTQTSATVSTKQPAPENSINTGSATAITETAEKSDKPQTETAASTEDASQHKANTVADNSVANNSESSEPKSRRRRSISQPQETSAEETTAASTDETTIADNSKRSKPNRRSRRSVRSEPTVTNGSDRSTVALRDLTSTNTNAVISDAMAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNENYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVRNSNNFDKASSKNTLAQVNFYSKYYADNHWYLGIDLGYGKFQSNLKTNHNAKFARHTAQFGLTAGKAFNLGNFGITPIVGVRYSYLSNANFALAKDRIKVNPISVKTAFAQVDLSYTYHLGEFSVTPILSARYDTNQGSGKINVNQYDFAYNVENQQQYNAGLKLKYHNVKLSLIGGLTKAKQAEKQKTAELKLSFSF
What is the function of this protein?
Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments.
What are the official names of this protein?
Immunoglobulin A1 protease autotransporter.
What are the subcellular locations of this protein?
[Immunoglobulin A1 protease autotransporter]: Periplasm. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease]: Secreted. Cell surface. SUBCELLULAR LOCATION: [Immunoglobulin A1 protease translocator]: Cell outer membrane; Multi-pass membrane protein. Note=The cleaved C-terminal fragment (autotransporter domain) is localized in the outer membrane.
Protein: RS5_BRASB
Sequence: MAGERERGGRDRKEREERDSEFVDKLVHINRVAKVVKGGKRFGFAALVVIGDQKGRVGFGHGKAREVPEAIRKATDSAKRNLTRVALREGRTLHHDIFGRHGAGRVYLRAAPAGTGIIAGGPMRAVFETLGIQDVVAKSIGSSNPYNMVRATFNALKHQDSPRSVAARRNIKVSTLQARRVGGDAEAAAD
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: LRL28_ARATH
Sequence: MYYHSLSSYSILFFLFSLFHHLPCASSNQGLGWCESLFQCGNITADFPFWGGNRHKPCGHPLLELHCNNNNITSLYISNQEFYVRQINQTSNTLTLARSDLLGSFCSSYAYNTTTLPPEIFELSPTYKSLTVLYHCDPKLSYRSSYTCPALGTFSMSQSVDYQYSCQNSFTVNVPTSFHPEERGLNLTNLESALRKGFEVKLVIDEIPCQQCSSTRGICSFNGTTQSCCNATSPSGGVSCVPYQHSADEVYRRCSESFSCGSQRDLNYPLWKPGREECGHPNFKLNCSGGFAEINIASVKFRILDSYRSLIRLARSDYIGDLCPANPLTAPFIEKFLPVLELTGETELLTLYYGCRFNSSDIPANIYVGELGCDEGRSYYVTRNLSSPLLDSSRGVLNNLREMCKRNVSVPASGPALFDLQTRPNQDNLKMALDQGFRMLITSDCERCRGSGGACGYNQTSSGFGCYCKDGKCGYEYDDGFFRRHRRFIATLVRYTFIALGALTGVVIVFLVLLCPCFRVQIFRKRKTSDEVRLQKLKALIPLKHYTYAEVKKMTKSFTEVVGRGGFGIVYSGTLSDSSMVAVKVLKDSKGTDGEDFINEVASMSQTSHVNIVSLLGFCCEGSRRAIIYEFLGNGSLDKFISDKSSVNLDLKTLYGIALGVARGLEYLHYGCKTRIVHFDIKPQNVLLDDNLCPKVSDFGLAKLCEKKESILSLLDTRGTIGYIAPEMISRLYGSVSHKSDVYSYGMLVLEMIGARKKERFDQNSRSDGSSIYFPEWIYKDLEKANIKDIEKTENGGLIENGISSEEEEIARKMTLVGLWCIQSSPSDRPPMNKVVEMMEGSLDALEVPPRPVLQQISASSVSDSFWNSEESSSASDILVFSTNSKLESSSL
What are the official names of this protein?
LEAF RUST 10 DISEASE-RESISTANCE LOCUS RECEPTOR-LIKE PROTEIN KINASE-like 2.8, Probable receptor-like serine/threonine-protein kinase LRK10L-2.8.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UL144_HCMVM
Sequence: MKPLVMLICFGVILLQLGVTKVCQHNEVQLGNECCPPCGLGQRVTKVCTERTSVTCTPCPNGTYVSGLYNCTDCTQCNVTQVMIRNCTSTNNTVCAPKNHTYFSTPGVQHHKQRQQNHTAHITVKQGKSGRHTLAWLSLFIFLVGIILLILYLIAAYRSERCQQCCSIGKIFYRTL
What is the function of this protein?
Activates NF-kappa-B in a tumor necrosis factor receptor (TNFR)-associated factor 6 (TRAF6)-dependent manner, causing the up-regulation of the chemokine CCL22.
What are the official names of this protein?
Membrane glycoprotein UL144, TNF alpha-like receptor UL144, UL144 protein.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PTH_SALDC
Sequence: MAIKLIVGLANPGAEYAATRHNAGAWYVDLLAERLRAPLREEPKFFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGTMASFYRIQPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTELWFKEGLAKATSRLHTFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALG11_CANAL
Sequence: MYLILLVVLAVYVTYKLITTVLPHHLLIPSQNWREKISYVVKYPKPIYLKVGTKRSSYRRRLILASENPAFYTNFINNKLKISPNDCENGDGFLNEMSRRDIDDPKRRIIYGFFHPYANNGGGGERVLWQAVKATLLADDKNICVIYTTNIEAQPLDILNKANKKFQIDGLDHSRVVFIYLRKFNNLIDGNYWKHFTLIGQLFGGILLSLEAMYELSPDVWIDTMGLPSSYLLVSLSLKIPILAYTHFPILQEDMFGKLKFQKLKDLWKFNIIKFNDYFALGKFIYWSILYYFYVYLGSKVNIALANGSWTFNHLSKIWVFNTALGNVLDVLYPPCGTEFLIKQANLNQPRSNKLLYLAQFRPEKRHALLLKEYSNFLSNNFPNVTQITNKFPTLVFAGSCRTADDTATLKFLQEQVAKLDLSRFVEFRIDISYDEVVELLSSCKFGLNAMWNEHFGIGVVEYMARGCTPIVHASAGPLLDMIGRNDQQENCLNNWKTDGGFFFKSYDDPDLDPNLQKNTETGYIKFELFDQFIDYPTFETLLKELYVNDPTIIEDSKLLKMRQIDQNRVAEKFSNKAFNKKWIEYINDLNTLEKQYREEKRTKVEQVY
What is the function of this protein?
Required for N-linked oligosaccharide assembly.  Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity).
What are the official names of this protein?
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Alpha-1,2-mannosyltransferase ALG11, Asparagine-linked glycosylation protein 11, Glycolipid 2-alpha-mannosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATG12_ASPCL
Sequence: MDSPSSENPSSGNSPPSNPPHLTGSKLSHRPASRRQDSESNTRSAPIPDDEHGADLPLTMSASVVLSSLPRDAHRALADAEAVDTGKVTVRFQPLPSAPILKNRVFKISASQKFETVVKFLRKKLDCKDTDSVFCYVNSVFAPGLDEGVGGLWRCFKVDDQLIVSYSMTPAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with atg5 through a ubiquitin-like conjugating system involving also atg7 as an E1-like activating enzyme and atg10 as an E2-like conjugating enzyme, is essential for its function.  The atg12-atg5 conjugate functions as an E3-like enzyme which is required for lipidation of atg8 and atg8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: CNIH4_MOUSE
Sequence: MEAVVFLFSLLDCCALIFLSVYFIITLSDLECDYINARSCCSKLNKWVIPELVGHTIVTVLMLVSLHWFIFLLNLPVATWNIYRFIMVPSGNMGVFDPTEIHNRGQLKSHMKEAMIKLGFYLLCFFMYLYSMILALIND
What is the function of this protein?
Involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory pathway, likely through interaction with the COPII machinery.
What are the official names of this protein?
Protein cornichon homolog 4, CNIH-4, Cornichon family AMPA receptor auxiliary protein 4.
What is the protein family that this protein belongs to?
Belongs to the cornichon family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment.
Protein: GDIR_CAEEL
Sequence: MSDHENTGENTSEYQYKQPPQKSIDELLNADKEDESLKVYKAKLLGQGTVIVDEKNPLRVIVRSVELLINGKTAQSFDLSDPAKLVNSDLSVSIKEGSNYRLSFAFHVQREITSGLHYKHKVKRSGITVENEKYMMGSYAPKLEIQEYKSPNEEAPSGMMHRGKYKVYSKITDDDNNVYLDWQWTLHITKE
What is the function of this protein?
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
What are the official names of this protein?
Probable rho GDP-dissociation inhibitor, Rho GDI.
What is the protein family that this protein belongs to?
Belongs to the Rho GDI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF2_MAIZE
Sequence: MSWQAYVDEHLMCEIEGHHLAAAAIVGHDGAAWAQSTAFPEFKTEDMANIMKDFDEPGHLAPTGLFLGPTKYMVIQGEPGAVIRGKKGSGGITVKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLLEQGM
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG.
What are the official names of this protein?
Profilin-2, Pollen allergen Zea m 12, ZmPRO2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: EIF2D_RABIT
Sequence: MFAKAFRVKSNTAIKGSDRRKLRADVAAAFPTLGTDQVSELVPGKEELNTVKLYAHRGDAVTVYVSGGNPILFELEKNLYPTVYMLWSHPDLLPTFTTWPLVLEKLVGGADLMLPGLVVPPAGLPQVQKGDLCAIALVGNRAPVAIGVAAMSTEEMLTSGLKGRGFSVLHTYQDHLWRSGDKSSPPSIAPLVVDPADLNDDKESVQVNPVLQGEEEGNGETALSEATSAGGQDQDPTDSRTLQEQMDELLQQCFLHALKCRIQKADLPLLTSTLLGSHMFSCCPEGHQLDIKKSSYKKLSKFLQHMQQEQIVQVKELSRGVESVVAVDWRHPRITSFVIPEPSLTSQSVQEGSREQPYRPPDIKPLYCVPASMTLLFQESGHKKGSVLEGSEVRAIIINYAKKNDLVDADNKNLVKLDPVLCDCLLEKHEQHSIMKLPWDSLVTRCLEKLQPAYQVTFPGQEPVVKKGKICPIDITLAQRASNKKVTVVRNLEAYGLDPGSVAATLQQRCQASTTVTPAPGAKDSLQVQIQGNQVHHLGRLLLEEYHLPRKYIQGLEHAPKASKKK
What is the function of this protein?
Translation initiation factor that is able to deliver tRNA to the P-site of the eukaryotic ribosome in a GTP-independent manner.  The binding of Met-tRNA(I) occurs after the AUG codon finds its position in the P-site of 40S ribosomes, the situation that takes place during initiation complex formation on some specific RNAs.  Its activity in tRNA binding with 40S subunits does not require the presence of the aminoacyl moiety.  Possesses the unique ability to deliver non-Met (elongator) tRNAs into the P-site of the 40S subunit.  In addition to its role in initiation, can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits.
What are the official names of this protein?
Eukaryotic translation initiation factor 2D, eIF2d, Ligatin.
What is the protein family that this protein belongs to?
Belongs to the eIF2D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3815_DICDI
Sequence: MFKLNFKNNYKVLTLLFSLTLSMFVSNAQVYYPGYLNNVSSISTVSADYFPLLVHNPPLTNSTTYSFNEAINLLDTVTDPIFNATQIQALLNTWASNVKAVIGLSLPIYVTQLNRINRIDLLSIQMYTETNSAFILSATTYAPLKPQGVSILNQVNAIKASLNGITLTTTQQAQLTQFNAAISKIQLSVSNSHLITFGANDVIPFNSDSLSYMEYIADDILTLDDAIDIIKQNNVRILNYIYDLYSTHKTLSLNF
What are the official names of this protein?
Uncharacterized protein DDB_G0285615.
What are the subcellular locations of this protein?
Secreted.
Protein: RL31B_NEIG2
Sequence: MKPNIHPDNYRTVLFFDSSANEGWLIRSCAGTHGKTMVWTDGKEYPLFSLDTSSSSHPVYTGKQRNVNTEGRASKFNQRFQSVMSSFRKDK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: MAS5_YEAST
Sequence: MVKETKFYDILGVPVTATDVEIKKAYRKCALKYHPDKNPSEEAAEKFKEASAAYEILSDPEKRDIYDQFGEDGLSGAGGAGGFPGGGFGFGDDIFSQFFGAGGAQRPRGPQRGKDIKHEISASLEELYKGRTAKLALNKQILCKECEGRGGKKGAVKKCTSCNGQGIKFVTRQMGPMIQRFQTECDVCHGTGDIIDPKDRCKSCNGKKVENERKILEVHVEPGMKDGQRIVFKGEADQAPDVIPGDVVFIVSERPHKSFKRDGDDLVYEAEIDLLTAIAGGEFALEHVSGDWLKVGIVPGEVIAPGMRKVIEGKGMPIPKYGGYGNLIIKFTIKFPENHFTSEENLKKLEEILPPRIVPAIPKKATVDECVLADFDPAKYNRTRASRGGANYDSDEEEQGGEGVQCASQ
What is the function of this protein?
Probably involved in mitochondrial protein import.  Is also required for efficient translocation of pre-pro-alpha-factor.  Involved in heme regulation of HAP1, as a component of the high-molecular-weight (HMC) complex.
What are the official names of this protein?
Mitochondrial protein import protein MAS5, Yeast dnaJ protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Note=Concentrated in a perinuclear ring as well as in the cytoplasm.
Protein: YFIV_BACSU
Sequence: MEYNLHDTTVLNENILSSEEREIWVLYMKVLTSAGLGDVSEWMKLDMSMPQMKVLMLLNNHGTLKVSDIAEKMGASLSNTTGLLDRLEKSGFVKRSHSEEDRRSVVVQLTENAKKIFRGLYEKGHLKLKRSLELLSPEEKQAVYEGLSILSRALENAKKE
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YfiV.
Protein: CBK_TRIVA
Sequence: MRIVVALGGNALLQRGMKGTFQDQQAACRLAMSQIVKIVKDGNELVMTHGNGPQCGAIFLQNVAGEQEKVPAMPLHVCGAETQGFLGELLQQELDGALRAEGIKKNVVSIVTQSFVDPKDPAFQNPTKPIGPFYSKEEAEFLRNERGYNMVEDAGRGYRMIVPSPVPQKFVEKEAIKTLVNSGFIVVCSGGGGIPVILDEQENRIEGVDAVIDKDLGASVLAAATNADAFMILTDVPEALLNYRKENETAIRQATVAEMEKYIEEGHFIKGSMLPKVQACLRFVKSTGKPALITALDCALQALKGERGTKIVPN
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
Protein: Y2650_ARATH
Sequence: MTTTPTSSGRRSISSIRRTSSASKKPVLQSEESESGSGSINENTSKPDSPLAQPVSDGERTVKKLRLSKALTINEGTTVFDACRRMAARRVDAVLLTDSSALLSGIVTDKDIATRVIAEGLRPEHTLVSKVMTRNPIFVTSDSLAIEALQKMVQGKFRHLPVVENGEVIALLDITKCLYDAISRMEKAAEQGSALATAVEERHWGSGNFAFIDTLRERMFKPALSTIVTENTKVALVSASDPVFVASKKMRDLRVNSVIIAVGNKIHGILTSKDILMRVVAQNLSPELTLVEKVMTPNPECASIETTILDALHIMHDGKFLHLPVFDKDGFAVACLDVLQITHAAISTVENNSSGAVNDMANTMMQKFWDSALALEPPEDYETHSDMSAMLINSEGKQSCPSQGLVSSFAFKFEDRKGRVQRFNSTGESFEELMSVVMQRCEADSGLQIMYQDDEGDKVLISRDSDLVAAVTFARSLGQKVLRLHLDFTETIAPLETIADLSEGNGGCVWWQTGVLAGAIVLTSIGLFVYLKRSKK
What are the official names of this protein?
CBS domain-containing protein CBSCBSPB2.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYFB_PROM9
Sequence: MKVSQNWLKNLVEISSTPVDLSEKLSIGGFEVESLEDCSKNVNGVVLGKVLSVLKHDGSDKLSICQVDIGTSKNLQIICGARNIKPNVYVYVATVGAKLNAVDLTIKRSEIRGVMSEGMICSLQELGLEDSSEGIEIIDEDLALKHELGTPVSDLLQLNDFIYDLAITANRPDGMSVIGIAREISALLESKLSFPELNHKYNIHLNKGIKLCPEAITSNCIYTISCIDGVNGNKLSPIWLKDRIEKSGIKSINLLVDLTNYILLEQGQPLHAFDKEKLSNLIGKDVSPEDFSVRKAKDNESLVCLDGKKYELNENITVVTCSDKPVAIAGVIGGLETSVSNTTSSIYLEGAVFNPVTIRKSSKAVGIRTESSSRYEKGISSKNTISAVTRAMNLLEEYFSINLPIINTSNLKNNEDIFIKLRRSRIHKILGPLIINDQFEKRNISDTEIVDKLTLIGCSLKSKEYGWDVAVIPNRSQDLIREIDLIEEIARLIGYDRFDLNLPNPIKPGKLSSEQLALRKVKNGFTENGFNEVLSYSLVPEDKETLIKISNPLLLETSCLRDNIWKEHLEIVNRNIKAGQNSCYIFEIGNVFHKNTEFIQKEVLNGAIFGNKRFEKWVNSNKDNDLNYYQARGKLKEALSSLNIKIDDKPTDSIDFLHPGRTAKLIIEGKDAGYFGEIHPKLILEKKSLKIVYLFSINVDNLLGASTRKNKWIPIFKQYPIVPKIERDINFVFSKKFLISDITSLIKKTGKNLLEDVYLIDIFEDIKLGEDYISYTFRLSYRAQDKTLLDSDIKTIHSSIISNIEKSFQTKLRN
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCAM1_MOUSE
Sequence: MEAAHFFEGTEKLLEVWFSRQQSDASQGSGDLRTIPRSEWDVLLKDVQCSIISVTKTDKQEAYVLSESSMFVSKRRFILKTCGTTLLLKALVPLLKLARDYSGFDSIQSFFYSRKNFMKPSHQGYPHRNFQEEIEFLNAIFPNGAAYCMGRMNSDCWYLYTLDFPESRVISQPDQTLEILMSELDPAVMDQFYMKDGVTAKDVTRESGIRDLIPGSVIDATLFNPCGYSMNGMKSDGTYWTIHITPEPEFSYVSFETNLSQTSYDDLIRKVVEVFKPGKFVTTLFVNQSSKCRTVLSSPQKIDGFKRLDCQSAMFNDYNFVFTSFAKKQQQQQS
What is the function of this protein?
Essential for biosynthesis of the polyamines spermidine and spermine.  Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme 1, AdoMetDC 1, SAMDC 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic AdoMetDC family.
Protein: PPNP_PSEA8
Sequence: MFKVNEYFDGTVKSIAFDMTAGPATIGVMAAGEYEFGTSQLEIMHVVAGALTVKLPGSDEWQEYASGSQFTVPANSKFQLKVAQDTAYLCEYR
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: PSBZ_CYAP4
Sequence: MTFLFQLALAALVILSFAMIVGVPVAYASPQNWDSSKRLIFLGSGVWIGLVLVVAALNFLVV
What is the function of this protein?
Controls the interaction of photosystem II (PSII) cores with the light-harvesting antenna.
What are the official names of this protein?
Photosystem II reaction center protein Z, PSII-Z.
What is the protein family that this protein belongs to?
Belongs to the PsbZ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein. Note=Associated with the photosystem II complex.
Protein: THRSP_MOUSE
Sequence: MQVLTKRYPKNCLLTVMDRYSAVVRNMEQVVMIPSLLRDVQLSGPGGSVQDGAPDLYTYFTMLKSICVEVDHGLLPREEWQAKVAGNETSEAENDAAETEEAEEDRISEELDLEAQFHLHFCSLHHILTHLTRKAQEVTRKYQEMTGQVL
What is the function of this protein?
Plays a role in the regulation of lipogenesis, especially in lactating mammary gland.  Important for the biosynthesis of triglycerides with medium-length fatty acid chains.  May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA.  May function as transcriptional coactivator.  May modulate the transcription factor activity of THRB (By similarity).
What are the official names of this protein?
Thyroid hormone-inducible hepatic protein, Spot 14 protein, S14, SPOT14.
What is the protein family that this protein belongs to?
Belongs to the SPOT14 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MENC_ECOLC
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.