PharMolix/UniProtQA huggingface dataset:
Protein: NUSB_RHIEC
Sequence: MNDDKTERPVKTANQRGAARLAAVQALYQMDVGGTGVLEIVAEYEAHRLGQEIDGATYLKADAGWFRSIVSGVVRDQVRLDPLIAVALQDDWALSRLDSTVRAILRAGVFELLDRKDVPVAVIVTEYVEIARAFFDDDEPKLVNAVLDRIAKQVRGEAKK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: NSP1_ROTWI
Sequence: MATFKDACYYYKRINKLNHTVLKLGVNDTWRPSPPTKYKGWCLDCCQHTDLTYCRGCTMYHVCQWCSQYGRCFLDNEPHLLRMRTFKNEVTKDDLMNLIDMYDTLFPMNQKIVDKFINNTRQHKCRNECMTQWYNHLLMPITLQSLSIELDGDIYYVFGYYDDMNNVNQTPFSFINLIDICDKLLLDDVNFTRMSFLPITLQQEYALRYFSKSRFISEQRKCVSDSHFSINVLENLHNPSFKIQITRNCSELSSDWNGACKLVKDTSAYFNILKTSHVEFYSVSTRCRMFTQRKLQIASKLMKPNYMTSNHRASATEVHNCKWCSTNSSYIVWNDFRVKKIYDNILNFLRALVKSNVNVGHCSSQEKIYECVENILDICDNEKWKTSVTEIFNCLEPVELNAVNYVLFNHEVNWDVINILVQSIGKVPQILTLNDVVTIMQSIIYEWFDIRYMRNTPMTTFTVDKLRRLCIEPKTVDYDSGISDVE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.  Recognizes the host NF-kappa-B regulator BTRC through the presence of a DSGXS motif in the C-terminal substrate recognition domain.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: DNAA_MYCSJ
Sequence: MTADPDPPFVAVWNTVVAELNGDPAATGPRNGDGALPTLTPQQRAWLKLVKPLVITEGFALLSVPTPFVQNEIERHLREPIITALSRHLGQRVELGVRIATPSPEDDDPPPSPVIADIDEVDEDTEARVSAEETWPRYFSRPPETPAAEDPNAVSLNRRYTFDTFVIGASNRFAHAATLAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKASFKRSYRDIDVLLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPELETRIAILRKKAQMDRLDVPDDVLELIASSIERNIRELEGALIRVTAFASLNKTPIDKSLAEIVLRDLISDASTMQISTAAIMAATAEYFETTIEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAEKKIRGEMAERREVFDHVKELTTRIRQRAKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_KLULA
Sequence: MFYLLNSIIMNDVPTPYGMYFQDSATPNQEGILELHDNIMFYLFIILGLVSWLLFTIVRTYSKNPIAYKYIKHGQTIEIIWTIFPAVILLIIAFPSFILLYLCDEVISPAMTIKAIGLQWYWKYEYSDFINDNGETVEFESYVIPEDLLEDGQLRLLDTDTSVVVPVDTHIRFVVTAADVIHDFAVPSLGIKIDAAPGRLNQVSALIQREGVFYGQCSEICGQSHSAMPIKIEAVSLPAFLEWLNEQ
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KGUA_SHEDO
Sequence: MSARGNLFIVSAPSGAGKSSLITALLKDKPQDMQVSVSHTTRAPRPGEVDGQHYHFVSVEQFKALIAENAFFESAEVFGNFYGTSRQVIENTLSLGIDVFLDIDWQGAQQVKKIMPEAIGVFILPPSKAELERRLTGRGQDSSDVIAARMAQAVSEMSHYNEYDFVIINDDFEQALADLKSIIFSQRLTCASQFHTHNDMLVDLLAD
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXTN_MAIZE
Sequence: MCPAFSIFFNSRRYSLTPPTYTPSPKPPTPKPTPPTYTPSPKPPASKPPTPKPTPPTYTPSPKPPTPKPTPPTYTPSPKPPATKPPTPKPTPPTYTPSPKPPTPKPTPPTYTPSPKPPATKPPTPKPTPPTYTPSPKPPTPKPTPPTYTPSPKPPTPKPTPPTYTPSPKPPTHPTPKPTPPTYTPSPKPPTPKPTPPTYTPSPKPPTPKPTPPTYTPSPKPPATKPPTPKPTPPTYTPTPKPPATKPPTYTPTPPVSHTPSPPPPYY
What is the function of this protein?
Structural component in primary cell wall.
What are the official names of this protein?
Extensin, Proline-rich glycoprotein.
What are the subcellular locations of this protein?
Secreted, primary cell wall.
Protein: H4_DROER
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GLMU_GEODF
Sequence: MAKVAAIVLAAGKGTRMKSELVKVMHPLSGMPMISWPVNVVREAGAAVITLVVGHQSEKVREFFADQGDIVFASQEEQLGTGHAVACCSEALSGFTGAILILCGDVPLITPETLQTFLEYHYRQQAVITVLTTCMDNPYGYGRVIKDAAGHVTEIVEEKDASAEQRQINEINSGIYCVDAGFLFTAVADLKNDNAQKEYYLTDIIKTAVAERRTCCAFPIADPMEVMGVNDRVQLAEAGRIIRVRINKALMVAGTTIIDPETTYIDHGVVVGRDTTIYPNVCISGGTVIGDNCVIESSAVIKGCKVGDCVTIKAGSVMEDSVIGNTVAIGPMAHLRSGTELRDEVKIGNFVETKKIIMGAGSKASHLTYLGDATIGSHVNIGCGTITCNYDGVKKHRTVIEDDVFVGSDVQFVAPVSIGRNSLIAAGTTVTKDVPPDSLAIARAPQVNKEGWKLKNK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_PROA2
Sequence: MPQLTRSAELFEKAKQFIPGGVNSPVRAFKSVGGTPIYMAKGQGAYMTDVDGNTYLDYVGSWGPFILGSMHPRITAALEHTLTKIGTSFGTPIEMEIEIAELLCQIVPSIEMVRMVNSGTEATMSAVRLARGYTSRDKIIKFEGCYHGHGDSFLIKAGSGALTLGAPDSPGVTKGTANDTLNAKYNDIESVRLLVNENKGNIAAIIIEPVAGNTGVIPAKPGFLQALRDLCTEEGIVLIFDEVMCGFRVALGGAQERYGVTPDLTTMGKIIGGGLPVGAFGGKREIMERIAPLGDVYQAGTLSGNPLALTAGLETLKILRDENPYPELERKAAFLEEGFRNNMNKLGLNYVQNRVGSMACLFFTETPVTDYDTAVTADLKKYGTYYHAMLDQGIYLAPSQFEAMFTSAVMTDEDLEKTVKANYVALQATQK
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S61A2_ONCMY
Sequence: MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSADPFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFGMIITIGQAIVYVMTGMYGDPSDMGAGICLLIIIQLFVAGLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKAFSPTTVNTGRGTEFEGAIIALFHLLATRTDKVRALREAFYRQNLPNLMNLLATVFVFGVVIYFQGFRVDLPIKSARYRGQYNTYPIKLFYTSNIPIILQSALVSNLYVISQMLSTRFSGNFLVNLLGTWSDTSSGGPARAYPVGGLCYYFSPPESFGSVLDDPIHAAIYICFMLGSCAFFSKTWIEVSGSSAKDVAKQLKEQQMVMRGHRETSMVHELNRYIPTAAAFGGLCIGGLSVMADFLGAIGSGTGILLAVTIIYQYFEIFVKEQSEMGSMGALLF
What is the function of this protein?
Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER).  Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides.
What are the official names of this protein?
Protein transport protein Sec61 subunit alpha isoform B.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TCEA_DEHM1
Sequence: MSEKYHSTVTRRDFMKRLGLAGAGAGALGAAVLAENNLPHEFKDVDDLLSAGKALEGDHANKVNNHPWWVTTRDHEDPTCNIDWSLIKRYSGWNNQGAYFLPEDYLSPTYTGRRHTIVDSKLEIELQGKKYRDSAFIKSGIDWMKENIDPDYDPGELGYGDRREDALIYAATNGSHNCWENPLYGRYEGSRPYLSMRTMNGINGLHEFGHADIKTTNYPKWEGTPEENLLIMRTAARYFGASSVGAIKITDNVKKIFYAKVQPFCLGPWYTITNMAEYIEYPVPVDNYAIPIVFEDIPADQGHYSYKRFGGDDKIAVPNALDNIFTYTIMLPEKRFKYAHSIPMDPCSCIAYPLFTEVEARIQQFIAGLGYNSMGGGVEAWGPGSAFGNLSGLGEQSRVSSIIEPRYGSNTKGSLRMLTDLPLAPTKPIDAGIREFCKTCGICAEHCPTQAISHEGPRYDSPHWDCVSGYEGWHLDYHKCINCTICEAVCPFFTMSNNSWVHNLVKSTVATTPVFNGFFKNMEGAFGYGPRYSPSRDEWWASENPIRGASVDIF
What is the function of this protein?
Catalyzes the reductive dechlorination of trichloroethene (TCE) to cis-1,2-dichloroethene (DCE) and of cis-1,2-dichloroethene to chloroethene (PubMed:10671186, PubMed:11097881).  The substrate specificity is broad, and the enzyme can dehalogenate various substrates, including 1,1-dichloroethene (1,1-DCE), 1,2-dichloroethane and 1,2-dibromoethane (PubMed:10671186, PubMed:11097881).  A variety of other haloalkanes and haloalkenes containing three to five carbon atoms are dehalogenated at lower rates (PubMed:11097881).  Trans-1,2-dichloroethene (trans-DCE) and chloroethene are degraded at rates which are approximately 2 orders of magnitude lower (PubMed:10671186, PubMed:11097881).  Titanium(III) citrate and methyl viologen can be used as reductants (PubMed:10671186, PubMed:11097881).
What are the official names of this protein?
Trichloroethene reductive dehalogenase, TCE-RDase, TCE-reductive dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the PceA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Note=Membrane-bound.
Protein: RPOA_CLOBB
Sequence: MLEIEKPIIECIEASEDGTYGKYVVEPLERGYGITLGNALRRILLSSLPGVATSSVKIDGVLHEFSTVQGVKEDVTELILNIKSLALRMNGEGPKVIYIDAKGPGEVTGADIKTDGDVEVVNKDLHIATLDDNGRLYMELTVNRGRGYVTQNKNKSDELPISSIAIDSIYTPVKKVNFTVDNTRVGQITDYDKLTLEIWTNGTIKIDEAISLSAKILIEHFKLFMSLTNNTNDVEIMIEKEEDKKEKVLEMTVEELDLSVRSYNCLKRAGINTVQELATKSMDDMMKVRNLGKKSLEEVERKLKELGLCLKLNDE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MOT6_HUMAN
Sequence: MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT
What is the function of this protein?
Proton-linked monocarboxylate transporter.  Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
What are the official names of this protein?
Monocarboxylate transporter 6, MCT 6, Monocarboxylate transporter 5, MCT 5, Solute carrier family 16 member 5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RNH2_DICNV
Sequence: MIAGVDEAGRGAWIGNVVAAAVILPNDYDLPDLTDSKKLSAAKRERLCAAIYEQAIAVACAWCSPEEIDQLNIHYATLCAMKKAVITLKVAPTEVLIDGKFAPELPFPTRTIIGGDALEPAISAASIVAKVTRDKQMIALDALYPDYGFAAHKGYGTQKHQQALRQFGVLPLHRRSYAPIAALLKNNKK
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMB_SYNJA
Sequence: MQLFHFHTPEQVPPAGIPACAVAIDVLRATTTIAAALAAGAEAVEVFADLQSLQAASRSWPASKRLLAGERGGKTVTGFDLGNSPREYTPERVRDQRIFMSTTNGTRTLQRLERIPVVITAALVNLGAVVEFLRRGAFAEVWLVGSGWEGAFALEDTACAGAVLHRLGCSWEQLGNDEAVAALALYQTWQDNLLGLLRRSSHGQRLLAISPENDSDLAYCAKLDRLSVVPQQVQPGVLALAG
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: SYD_YERPP
Sequence: MRTEYCGQLNLSHVGQSVTLCGWVNRRRDLGGLIFIDMRDREGIVQVFFDPDHKAAFEQASELRNEFCIQITGTVRARPDSQINKDMSTGEVEIFANTLNIINRSEPLPLDSNQINSEEQRLKYRYLDLRRPEMADRLKSRAKITSFVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMSADQVREVMEKLVRELWQETKGVDLGDFPVMTFAEAMRRYGSDKPDLRNPLELVDVASLVKDVEFKVFSGPANDAKGRVAALRVPGGAQLSRKQIDEYGQFVGIYGAKGLAWLKVNDRAAGLEGVQSPIAKFLSAEVLDAILVATQAESGDILFFGADSYKIVTDAMGALRLKVGRDLELTRLGTWAPLWVVDFPMFEDDSEGGLTAMHHPFTAPKDMSPEQLAAAPTTAIANAYDMVINGYEVGGGSVRIHRTEMQQTVFGILGITEDEQREKFGFLLDALKFGTPPHAGLAFGLDRLVMLLTGTDNIRDVIAFPKTTAAACLMTDAPSFANPASLQELSISVVAKKGTTDAGAEENQ
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_MYCLB
Sequence: MTRMLPGYFPSPPRGVWHLGPLPIRAYALLIILGIVAALVVGGRCWEARGGERDVTYDIALWAVPFGLVGGRLYHLATDWRTYFGQNGAGLGAALRIWDGGLGIWGAVALGCVGAWLGCRRHRIPLPAFGDALAPGIILAQAIGRLGNYFNQELYGRETTMPWGLEVFYRRDPAGYMDPHSLDGVSTGQLAFVVQPTFLYELIWNVLVFFALIYVDRWFTLGHGRLFATYVAAYCIGRFCVELLRDDAATHIAGIRINSFTSTFVFIGAVVYIILAPKGREEPENLCRAEYVAREIPEPESATERATVASTYATTTAVPVSADEEFAETN
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NU4LM_AVALA
Sequence: MPSIFTNIILAFATALLGTLVFRSHLMSSLLCLEGMMLSLFTLSTLIILNMHLTMSFMMPILLLVFAACEAAIGLALLVMVSNTYGLDYIKNLSLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CCR5_PYGNE
Sequence: MDYQVSSPTYDIDYYTSEPCQKVNVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLIMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEHEISVGL
What is the function of this protein?
Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level.  May play a role in the control of granulocytic lineage proliferation or differentiation.  Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.
What are the official names of this protein?
C-C chemokine receptor type 5, C-C CKR-5, CC-CKR-5, CCR-5, CCR5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: H4_CHITH
Sequence: MTGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NS3_MYCTU
Sequence: VVAFERAK
What are the official names of this protein?
30 kDa non-secretory protein 3.
Protein: YQGF_NITEC
Sequence: MPDSAEETISDMASVILSGTVLAFDFGVRRIGVAIGEYELRLAHPLMTIDQAMTKPRFEKIAELIETWQPVLLVVGLSVHADGAEHEITRLCQRFARRLEGRFGIPVVMEDERYTTAIARLTLEEVGITGRKQRPMLDQIAAQHILQTFFDSSHAAS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_ECO55
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RECA_CAUVN
Sequence: MTSQAALKLVAKEEGDKQRALEAALAQIDRAFGKGSVMKLGEKGKVEIESVSTGSLGLDIALGIGGLPKGRIVEVYGPESSGKTTLALHVVAEVQKAGGTAAFVDAEHALDPSYAYKLGVNLDNLLVSQPDNGEQALEITDTLVRSGAVDIVVVDSVAALTPKAEIEGEMGDSLPGLQARLMSQALRKLTASINKANTIVIFINQIRHKIGVMYGSPETTTGGNALKFYASVRLDIRRTGSVKARDEIVGNNVRVKVVKNKVAPPFREVEFDIMYGEGISKLGEVIDLGVKAGIIDKAGSWFSYGSQRIGQGRDNVREFLKNNPDVAADIEKAVRKSSQKIEEELLVGGPEEGEED
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VELB_GIBZE
Sequence: MSQRMPGPGYSSSVPPPIHAYQQQQQHQHPPPSLLPPPPTQHHHSSHAPPPPPPPSSSSHSLSSHQHHAPPPPHHHSQLPPYPPTQYQQPHPNQYPRPHPLPPSRNDEPPPPSSEPSPSDQHEKPKYEPPSVSKIEEGTGLKYSLDVQQQPIRARMCGFGDKDRRPITPPPCVRLVIINSETGKEVDYNTLDHAMFVLSVDLWDKDGIKEVNLVRSSTGPGSGASSNNYSYSTLEPSTPSYQQQALPPSRESGYPQGQGLGYAQEYPPSVQQGYGQAPSYQSSSSYGPPQQYFPRHSGYNTDPPASSANPLFRNGYGQDQNALTRMAVVGTQPQGMFTRNLIGSLAASAFRLNDTDKKAGIWFVLQDLSVRTEGTFRLRFSFVNVGGAGGGLPIHVNQGRAPILASCYSQDFSVYSAKKFPGVCESTPLSKTFALQGIKIPIRKDTNIKGEGDEEMMYDQN
What is the function of this protein?
Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity).  The velvet complex acts as a global regulator for secondary metabolite gene expression (By similarity).  Component of the velB-VosA heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity).  The complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity).  Controls the expression of the pink pigment aurofusarin and the mycotoxin deoxynivalenol gene clusters (PubMed:22713714).  Regulates hyphae formation, hyphal hydrophobicity and conidiation (PubMed:22713714).  Regulates of cell wall integrity and pathogenicity (PubMed:22713714).
What are the official names of this protein?
Velvet complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the velvet family. VelB subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nuclear localization is mediated by veA (By similarity).