PharMolix/UniProtQA huggingface dataset:
Protein: APOE_CTESO
Sequence: MKVLCTVLVVTLLAGCQADVQPEPEALEPAVRKSDQPWELALGRFWDYLRWVQTLSDQVQEELLSSQVTQELTVLMEDTMKAVKAYKSELEQELVPMAEDTKARLSKELQAAQARLGADMEEVRNRLAQYRSEMQAMLGQSAEELRARLASHLRKLRKKLLRDAEDLQKRLAVYKDGASEGAERSVSAVRERLESLVEQSRARAALTSQPLQERAQAWGKRLRGRLEEVGSQARDRLEEVREQMEEVRVKMEEQAEAFQARLKGWFEPMVEDMRRQWADLIEKVQAAVGASTPTPSQKP
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: MURA_THESQ
Sequence: MGKLVVQGGTVLEGEVEISGSKNAALPIMAAAILCDEEIILKNVPRLQDVFVMIDILRSIGFRVEFDENELKIKRENDISQEVPYELVRKMRASFNVLGPIAVRTGRAKVALPGGCSIGVRPVDFHLEGLKKMGFSIKVEHGFVEATFERRTDQVTITLPFPSVGATEHLMTTAALLEGTRVVIENAAMEPEIVDLQNFINRMGGRIEGAGTSRIVIEGVEKMQGVEYSIIPDRIEAGTYLVAIAASRGKGLVKNVNPDHLTNFFEKLEETGVKLKVFGNEVEIEMRERPEAVDVTTNPYPGFPTDLQPQMMAYLSIASGVSVITENVFKTRFLHVDELKRMGADIEVSGNVAIVKGVEKLSGAPVEGTDLRATAALLIAGIIADGVTEISNVEHIFRGYEDVIDKFSKLGAKIEYVEKEN
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3M_EMENI
Sequence: MPAPSTTLLIEGSFSELAEEFAAYLDALNKPDDTTVQTEVAPLLQPLREQEQNDTQLDQSKRDEVLKKLVSAATVLNTAPEKEITPAYNLLIHLVQQASDPDMFLSRICSYLAKPIPSSPQFGASLSIAILSTIFNTLAPTDSSRFHVLLAIVTVIRQSGSSAAFDALKPQLTAQLPNWRSTWELDDEEARRLHLAIADAAQAAGDLDWAQTHVVDALQTIPPAEASSPAARDLAVRALTSALTHPAVFDFTPLTAADAVQALRSSDAPLFELLEIFTADTLDAYEDFISATPVENILPDNALAPHAEALQTKIRLLTLASLAAAATTTTGPSARSLSYETIASALRVPQEEVEKWVIDTIRAGLVEGKLSQLRSEFLVHRATYRVFGEKQWAEVQGRLMVWRRSLENVLGVIRSERERFVREAAAAAAAAAAEGEKGDKNNKGPSERRRAPQEIAAAE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit M, eIF3m.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit M family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP7_CAEBR
Sequence: MCSPDPEDMHILTNDIPSFDKSLDPYGPEGHLALDIERFSSFMNKPDSRIMSKPVIVRGIPWRILAICRHQQNNRQVATSRSRNNYNFGFFLQCNNDDLLQKRGMWRCYGQATLEVLNANGPPIQKKIHHSFHNTEVDWGFSNYDQYDTLTSPKDGYVIDDVIRLRCRFTADVPTGANYMWDSKKHTGCIGLRNQGATCYMNSILQSFYFTTGFRRAVYNMEVGTEPNESNIVLAMQRVFYELQMSSEAVETNSLTRAFGWDKLDAFNQHDVQEFCRVLLDNLETKMKGTSEEKSIPNLFRGNMKSYIKCLDVDYESSRTESFYDVQLNVLGMDSLERAFDAYTTPETLDDDNKYDAGDHGLQRAEKGVKFVELPPVLHVQLMRFQYCGVEQKINERFSFPEKMNLSNCCELGPMLNEEDCVYSLHAVLVHSGEFHGGHYVTYINVNLHESAVDPTATAKWCKFDDDVVSRTTTDDAIVSNFGGEKAMNSSAYMLVYVRDNAIDQVLAPIPDTQIPQSVSRTFEMERMHRNREKKKQEEEQMCMSITLVTPDILATNHSFDLIEPVTITDVLPHETVYKHMVTAELYQFVQEKLFEKSTLPKVDMFDSDDETRMKRKEILRRLKTKKFGFRLWRMTDSYTVDKPQKMASRLRPSDFIEYSIDTRLDHTLSHDTETIYVEHSQFLQPLNEYLPTRDILFFLKYYDAITDKFTIIGHVTLDSHKRLNLYRMTFCDLLGLPKDTELKYYIEHAPNHVEQIDDPNRSTISRLVDDQDGAIVIVEKADPTAKKDAKTKMIELYNDVEFEFSQQFYSKMPNEEPFELFTKRFCLEQKLTDVTEFIGSELNVDPRNVMLWTRVSGSRFEPNFDDYAVTGIQCKYLTLRTLHDPRQHKKYSVSYAIFPFPVNEVHTTRMFVRLYRQMPNGNVEELNLFPPKDGTVTDLIAEAKRYYPSVEGGSGKFRLLQIGTSPLNNQRVFQIYNENTAIVDLDQRPVYKQQAQHTLNCRIEEIPHDELDVAQGEFFCPVVHYDREPTKLFGVSFVIKIRNGELMTDVRDRLRRKLPDVSDAEFAKYKFALLSRDKLCRNIEFNAGEKVNLMDMANQTTGVPQVYIGLDHKSPSQHSNEAAIRILN
What is the function of this protein?
Hydrolase that deubiquitinates target proteins.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 7, Deubiquitinating enzyme 7, Ubiquitin thioesterase 7, Ubiquitin-specific-processing protease 7.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TPIS_ENTFA
Sequence: MRKPIIAGNWKMNKTLSEAQSFAEAVKNAVPSNDVVDAVIGSPALFLAPLAWNLKDSEVKLAAQNCYWENAGAFTGENSPAAIADLGVDYVIIGHSERREYFHETDEDINKKAKAIFANGMTPIFCCGETLETYEAGKTAEWIEGQITKGLVGLSNEQVASMVIAYEPIWAIGTGKSADANIADEICGVVRSTVEKLYGKEVSEAVRIQYGGSVKPENIAEYMAKENVDGALVGGASLEADSFLALLDAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUH_DROSI
Sequence: NPNGSPLDPHQQQQQQQSQDMPHFGLPGPQPPSSQQQQQQMQVHHQQQQQQQQQQQHQQQMQMSLLPGPYRPHIEEKKLTRDAMEKYMRERNDMVIVILHAK
What is the function of this protein?
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations.  Binds directly the 5'-GTGRGAR-3' DNA consensus sequence, which is present in the regulatory region of several genes.  Required for neurogenesis in imaginal disks.  Acts as a transcriptional repressor when it is not associated with Notch proteins.  When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes.  Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively.  Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.  Required for transcription of Sim.  Also functions independently of Notch pathway, in the development of the bristle sensory organ precursor cell (By similarity).
What are the official names of this protein?
Protein suppressor of hairless.
What is the protein family that this protein belongs to?
Belongs to the Su(H) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=In imaginal disk, at the onset of differentiation of socket cell, it is also present in the cytoplasm.
Protein: RBFA_OENOB
Sequence: MPKHAKSARLLRVEGTIQREISEILVKEVSDPRLKDVTITGIDMTPDFSIAYVYWTIYSDLASSGEKADAGLQAAKGLIKRQLARKMTTFKIPDLIFKRDTAIEYGDHIEQLIAKLNHESK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_CYAM1
Sequence: MAVPKKRTPKSKTRSRKSQWMRKALKQLQKARTLAGRLAARQDQMQPTQMQPTQMQPN
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TGT_CLOPE
Sequence: MTKKRYTLLKKDGKARRGEFVTPHGTIQTPIFMNVGTLAAIKGAVSSMDLKEIGCQVELSNTYHLHLRPGDKIVKQMGGLHNFMNWDRPILTDSGGFQVFSLAGMRKIKEEGVYFNSHIDGRKIFMGPEESMQIQSNLGSTIAMAFDECIPNPSTREYVEKSVARTTRWLERCKKEMDRLNSLDDTVNKEQMLFGINQGGVYEDIRIEHAKTIREMDLDGYAIGGLAVGETHEEMYRVIDAVVPHLPEDKPIYLMGVGLPSNILEAVERGVDFFDCVLPARNGRHGHVFTKEGKINLMNAKFELDARPIDEGCQCPACKNYTRAYIRHLFKAKEMLAMRLCVLHNLYFYNKLMEDIRDAIDGGYFAEFKAKKLEEWNGRA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: FDHD_ECODH
Sequence: MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_JANSC
Sequence: MARDRRPAKKKVSKNIAAGVAHVNSSFNNTKILISDVQGNAIAWSSAGTMGFKGSRKSTPFAAQMAAEDAGKKAQDHGVRTLEVEVQGPGSGRESALRALAALGFQISSIRDVTPMAHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: GLGA_STRS7
Sequence: MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVFVILPYYDVVDQAFGHQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQAYFFRGRIYGDWDDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVFTIHNIAFQGQFDPGMLGDLFGVGIGRYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSYAHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAATKQVLQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELSHILQQDVQLVLLGTGDPDYEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGAIPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTIQQHAMTKDFSWDTASLAYLDLYKSLL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: VF226_ASFB7
Sequence: MKMETFLVCLFHNADGLHQQIQEILYLLRMHIYETNLYLKQELSRLIYPNRQLSFVLLMPLSLLRNWDDIEYLTDVVDDKQTLHYAANLLTNYVLHLSMFQKLTKPYFLLAVKRVSEKLNKRQRHSFYEVLVTSETLNNYENLSKNILNTLMFAVRYVFKPTPNYSEILAELEKKNKIHHIIFNMVIADFAQIRKQQMDKHLCETNNELRQECKETIFDLKVVGNV
What is the function of this protein?
Plays a role in the inhibition of host NF-kappa-B and IRF3 signaling pathways.  Mechanistically, promotes the degradation of host IKBKG through enhancing its ubiquitination leading to inhibition of both pathways.
What are the official names of this protein?
Late protein I226R, pI226R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I226R family.
Protein: IBOC_AMAMK
Sequence: MTLQSESRFYYQLLAAVLIPALFVAWAARLRQNRKYPPGPKGIPIFGNLFQLSTRPWIEFSAFKEQYGPLVYLNIVGQPLLITNTHTAATDLFDRRGGVYSDRPRSIVADYLTGGLYLPFARHGPTWLKLRRAGHAFMHKGVAHKYRDTQFKEALTLTHHLLQSPSGRRRQLFESAEASIHSIVYDQPSSGGPVYPKMTDFSTLINKAVTPLFTPAEFLPLMQYVPSWLAGWKRRAQQGFVLFSELCEGLLEEVAKRVDAGDDRPSMAGGLIREREKHGLTNLEAAWLSGMMILVGTETNTLAMSWFLYAMIAYPDKQKRCQAELDAVVGRSRMPTFEDLEKLPYLRATIREILRWRPSIPVGARHYTTKDDWYQGYFIPKGTICFPNVWSLNHDPAIYGTDADHFNPGRFIDKDGGLSPAIPATKDGAFLIPHHDLHNSHGLNPPKMQKVCLRFIDLHTFRSKYPLSIAVPGHVSYGFGSRICLGRHIANDALFINFASILWATSISPAMNANTGKPDVPDKLAYSNLGLLIVPTTTECVIQPRFDEAEGILAQTRELCM
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the psychoactive metabolites ibotenic acid and muscimol (PubMed:32233056).  The first committed step is glutamate hydroxylation by the 2-oxoglutarate-dependent dioxygenase iboH, and the last step is decarboxylation of ibotenic acid to muscimol by the decarboxylase iboD (PubMed:32233056).  The order of the intermediate reactions is somewhat ambiguous (Probable).  IboA likely activates the carboxylic acid at position 5 to introduce an amide bond, and the flavin monooxygenase iboF generates the N-O bond (Probable).  There are several options for the latter step (Probable).  One option is that iboF directly hydroxylates the amide nitrogen formed by iboA to produce a hydroxamic acid species (Probable).  Another option is that iboF hydroxylates an external N-containing compound, whose resulting N-O bond is subsequently introduced into the hydroxyglutamate scaffold (Probable).  The paralogous PLP-dependent cystathionine gamma-synthase-like enzymes iboG1 and iboG2 are likely involved in substitution of the OH group at position 3 by the O-N moiety (Probable).  The first cyclic intermediate is most probably tricholomic acid which is likely desaturated to ibotenic acid by the cytochrome P450 monooxygenase iboC (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase iboC, Ibotenic acid biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GLNB1_METMI
Sequence: MKMIRAVVRPSKAEEVVDALAESGCLALTKMDVIGRGKQKGIKIDQIYYDELPKTMLMLVVEDDTAENVIELITKTAYTGSFGYGKIFVSPVDEAYTVRTRSCGL
What is the function of this protein?
Could be involved in the regulation of nitrogen fixation.
What are the official names of this protein?
Nitrogen fixation nifHD region glnB-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: RL11_LEGPA
Sequence: MAKKVEAYIKLQIPAGKANPSPPVGPALGQRGVNIMEFCKAFNAATQQMEQGLPIPVVITVYSDRSFTFITKTPPASVLLKKAAGIQSGSGTPNTKKVAKLNVSQLEEIAKVKKPDLTAADLAAAVRSIAGTARSMGIEVEGLE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PP220_ARATH
Sequence: MYFRVLLTPSSAMFDSFSFVRRLSYSPDLGRRIYGHVLPSHDQIHQRLLEICLGQCKLFKSRKVFDEMPQRLALALRIGKAVHSKSLILGIDSEGRLGNAIVDLYAKCAQVSYAEKQFDFLEKDVTAWNSMLSMYSSIGKPGKVLRSFVSLFENQIFPNKFTFSIVLSTCARETNVEFGRQIHCSMIKMGLERNSYCGGALVDMYAKCDRISDARRVFEWIVDPNTVCWTCLFSGYVKAGLPEEAVLVFERMRDEGHRPDHLAFVTVINTYIRLGKLKDARLLFGEMSSPDVVAWNVMISGHGKRGCETVAIEYFFNMRKSSVKSTRSTLGSVLSAIGIVANLDLGLVVHAEAIKLGLASNIYVGSSLVSMYSKCEKMEAAAKVFEALEEKNDVFWNAMIRGYAHNGESHKVMELFMDMKSSGYNIDDFTFTSLLSTCAASHDLEMGSQFHSIIIKKKLAKNLFVGNALVDMYAKCGALEDARQIFERMCDRDNVTWNTIIGSYVQDENESEAFDLFKRMNLCGIVSDGACLASTLKACTHVHGLYQGKQVHCLSVKCGLDRDLHTGSSLIDMYSKCGIIKDARKVFSSLPEWSVVSMNALIAGYSQNNLEEAVVLFQEMLTRGVNPSEITFATIVEACHKPESLTLGTQFHGQITKRGFSSEGEYLGISLLGMYMNSRGMTEACALFSELSSPKSIVLWTGMMSGHSQNGFYEEALKFYKEMRHDGVLPDQATFVTVLRVCSVLSSLREGRAIHSLIFHLAHDLDELTSNTLIDMYAKCGDMKGSSQVFDEMRRRSNVVSWNSLINGYAKNGYAEDALKIFDSMRQSHIMPDEITFLGVLTACSHAGKVSDGRKIFEMMIGQYGIEARVDHVACMVDLLGRWGYLQEADDFIEAQNLKPDARLWSSLLGACRIHGDDIRGEISAEKLIELEPQNSSAYVLLSNIYASQGCWEKANALRKVMRDRGVKKVPGYSWIDVEQRTHIFAAGDKSHSEIGKIEMFLEDLYDLMKDDAVVNPDIVEQGSLDCV
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At3g09040, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-E subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TUSC_SALPC
Sequence: MKRIAFVFSTAPHGSTSGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLENVNFVVDATPLEPVALRRELGNYDVILRF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
What are the official names of this protein?
Protein TusC, tRNA 2-thiouridine synthesizing protein C.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJIX_ECO57
Sequence: MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSYEEFFRERQNARYGGDGKGGMRCC
What are the official names of this protein?
Uncharacterized protein YjiX.
What is the protein family that this protein belongs to?
To E.coli YbdD.
Protein: RS10A_YEAST
Sequence: MLMPKEDRNKIHQYLFQEGVVVAKKDFNQAKHEEIDTKNLYVIKALQSLTSKGYVKTQFSWQYYYYTLTEEGVEYLREYLNLPEHIVPGTYIQERNPTQRPQRRY
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:22096102).  eS10 plays a role as a positive regulator of the GCN2 kinase activity by stimulating GCN1-mediated GCN2 activation (PubMed:25437641).
What are the official names of this protein?
40S ribosomal protein S10-A, Small ribosomal subunit protein eS10-A.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPSA1_ORYSJ
Sequence: MAGNEWINGYLEAILDSGGAAGGGGGGGGGGGGGGGGGGGGGGGGVDPRSPAAGAASPRGPHMNFNPTHYFVEEVVKGVDESDLHRTWIKVVATRNARERSTRLENMCWRIWHLARKKKQLELEGILRISARRKEQEQVRRETSEDLAEDLFEGEKADTVGELAQQDTPMKKKFQRNFSELTVSWSDENKEKKLYIVLISLHGLVRGDNMELGRDSDTGGQVKYVVELARALAMMPGVYRVDLFTRQVSSPEVDWSYGEPTEMLTSGSTDGEGSGESAGAYIVRIPCGPRDKYLRKEALWPYLQEFVDGALAHILNMSKALGEQVSNGKLVLPYVIHGHYADAGDVAALLSGALNVPMVLTGHSLGRNKLEQIMKQGRMSKEEIDSTYKIMRRIEGEELALDAAELVITSTRQEIDEQWGLYDGFDVKLEKVLRARARRGVSCHGRFMPRMVVIPPGMDFSSVVVPEDTSDGDDGKDFEIASPRSLPPIWAEVMRFLTNPHKPMILALSRPDPKKNITTLVKAFGECRPLRELANLILIMGNRDDIDEMSAGNASVLTTVLKLIDKYDLYGSVAFPKHHKQSDVPEIYRLTGKMKGVFINPALVEPFGLTLIEAAAHGLPIVATKNGGPVDIKNALNNGLLVDPHDQHAIADALLKLVADKNLWQECRKNGLRNIQLYSWPEHCRTYLTRIAGCRIRNPRWLMDTPADAAAEEEEALEDSLMDVQDLSLRLSIDGERGSSMNDAPSSDPQDSVQRIMNKIKRSSPADTDGAKIPAEAAATATSGAMNKYPLLRRRRRLFVIAVDCYGDDGSASKRMLQVIQEVFRAVRSDSQMSRISGFALSTAMPLPETLKLLQLGKIPPTDFDALICGSGSEVYYPSTAQCVDAGGRLRPDQDYLLHINHRWSHDGAKQTIAKLAHDGSGTNVEPDVESCNPHCVSFFIKDPNKVRTIDEMRERVRMRGLRCHLMYCRNATRLQVVPLLASRSQALRYLFVRWGLSVGNMYLIVGEHGDTDHEEMLSGLHKTVIIRGVTEKGSEQLVRSSGSYQREDVVPSESPLIAFTKGDLKADEIMRALKEVTKAASGM
What is the function of this protein?
Plays a role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate.  Involved in the regulation of carbon partitioning in the leaves of plants.  May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf.  Plays a role for sucrose availability that is essential for plant growth and fiber elongation (By similarity).
What are the official names of this protein?
Probable sucrose-phosphate synthase 1, Sucrose phosphate synthase 1F, OsSPS1F, UDP-glucose-fructose-phosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family.
Protein: SYP_SPHAL
Sequence: MQKRNRRDVVPHPSIETGPMIKHALSVTRQADFAAWYQDVIAEADLAEESGVRGCMVIKPWGYGIWERIQTVMDAAIKDAGVQNAYFPLFIPLSFFEKEADHVDGFAKEMAVVTHHRLIADSKGKLVPDPEAKLEEPLIVRPTSETVIGAAMSRWVQSWRDLPLKVNQWANVVRWEMRTRMFLRTSEFLWQEGHTAHADRDDAMAETLRALEMYRSFAEDVLAMPVIAGEKPENERFPGAVATYSIEAMMQDGKALQAGTSHYLGTGFAEAAGIRYQDRDGGHSLCHTTSWGTSTRMIGGVIMTHGDDDGLRCPPRIAPHQIVIVPMLRDNGEDAAILDYCRDLESRLKALDAFGEPVRVLLDTGANKAQTKRWGWVKKGAPIIVEVGPRDVAGGNVAVIRRDRLYQESGKLNSAFVAKGDFIADAAATLEDIQASLYAEARERLDANIRRDVTDLAAHFSGEDRFVGWAEVQWARPTGGALDRIVEQLKALKLTMRNTPLDAAPADSACIFTGEPAVERVLIGRTY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.