PharMolix/UniProtQA huggingface dataset:
Protein: IFT57_HUMAN
Sequence: MTAALAVVTTSGLEDGVPRSRGEGTGEVVLERGPGAAYHMFVVMEDLVEKLKLLRYEEEFLRKSNLKAPSRHYFALPTNPGEQFYMFCTLAAWLINKAGRPFEQPQEYDDPNATISNILSELRSFGRTADFPPSKLKSGYGEHVCYVLDCFAEEALKYIGFTWKRPIYPVEELEEESVAEDDAELTLNKVDEEFVEEETDNEENFIDLNVLKAQTYHLDMNETAKQEDILESTTDAAEWSLEVERVLPQLKVTIRTDNKDWRIHVDQMHQHRSGIESALKETKGFLDKLHNEITRTLEKISSREKYINNQLENLVQEYRAAQAQLSEAKERYQQGNGGVTERTRLLSEVMEELEKVKQEMEEKGSSMTDGAPLVKIKQSLTKLKQETVEMDIRIGIVEHTLLQSKLKEKSNMTRNMHATVIPEPATGFY
What is the function of this protein?
Required for the formation of cilia.  Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity).  Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis.  Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.
What are the official names of this protein?
Intraflagellar transport protein 57 homolog, Dermal papilla-derived protein 8, Estrogen-related receptor beta-like protein 1, HIP1-interacting protein, MHS4R2.
What is the protein family that this protein belongs to?
Belongs to the IFT57 family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Note=Concentrates within the inner segment of cilia.
Protein: TRPA_HAEIE
Sequence: MSRFETQFATLNAKNEGAFVPFVTLCDPTFDRSFEIICTLVDNGADALELGFPFSDPLLDGPVIQAANNRALTAGHSSEDSFKLLEKVRSKYPEIPISLLLCANLIFAKGLDAFYQRCAEVGVDAVLVADIPLLAKEDYVQAAKKHGIQPVFICPPNADEKTIQGVAKNSEGYTYLVSRAGVTSAENQAHAANLDTLVEQLKAHNAPPILQGFGIAQPAQVKEALALGAAGAISGSATVKIIERNLDNHEQCLAELAEFVQTMKAATK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: YEAH_SALNS
Sequence: MTWFIDRRLNGKNKSTVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTDDISEPMFHQGRGGLRHRVHPGNDHFIQNDRIERPQGGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKKNQHRQLNEYKTHRAGFTSNGVPANISVVRSLQNSLARRTAMTAGKRRELHALETELETISHSEPAQLLEEERLRREIAELRAKIERVPFIDTFDLRYKNYEKRPEPSSQAVMFCLMDVSGSMDQATKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYDPGQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQATFDNFAMQHIRDQEDIYPVFRELFQKQSANQSA
What are the official names of this protein?
UPF0229 protein YeaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: COMD4_DICDI
Sequence: MTNIRIKLLTVQVITSLASGENIDFEKVEKLVKDAGFVIGDIKALIAAIHFIIFNSVKNDVDESTLSTELQQLGLPKEHCDSISRAFREHKEKLRSIFHNNTLKLPSLHSLDWRVDFILSSNTIQEVNSPSVQLNFKVKNHSNNEITNHPFEISAKKFNVLYYELKGAKLLMETVNQ
What are the official names of this protein?
COMM domain-containing protein 4.
Protein: FZD8_CHICK
Sequence: AGAAELQPELAVAEHVRYESTGPALCTVVFLLVYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLLPSVKSIAVLALSSVDGDPVAGICYVGNQSLENLRGFVLAPLVVYLFTGSLFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFTVLYTVPATIVIACYIYEQHNREAWEQAQNCSCPGDPHRPKPDYAVFMLKYFM
What is the function of this protein?
Receptor for Wnt proteins.  Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
What are the official names of this protein?
Frizzled-8, Fz-8, cFz-8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: GCH4_RUEST
Sequence: MNIHSRDVNETPDRSDAEQALAVLRRWAGEASETEVAQLDPAIARLLPGQELQNYPDLKRQYPDDFDANESYRATLPDLQNGPSSLIRGAKEQIQHVGISNFRLPIRFHTRDNGDLTLETSVTGTVSLDAEKKGINMSRIMRSFYKHAEKVFSFDVMEAALEDYLSDLESGDARLQMRFSFPVKVQSLRSGLSGYQYYDVALELVQMAGQRHRIVHLDYVYSSTCPCSLELSEHARQARGQLATPHSQRSVARISVQMEQDGGCLWFEDLIDHCRRAVPTETQVMVKREDEQAFAELNAANPIFVEDAARLFCEALQSDARVGDFRVVASHQESLHSHDAVSVLTQGTMFAAPSLDPQLFSTLIHRG
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RBFA_DEHMC
Sequence: MSRRIKKLNQLFRADISALLQKEIRDPRLDTLLSVNEVDISEDMRHANVYVSHLAGDEHKDEILAALNAAAGFFRTEIAKKTDIRYMPVFHFVWDITIERGVRLNTLIDQVIHHQPED
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K2C75_HUMAN
Sequence: MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQKSYTH
What is the function of this protein?
Plays a central role in hair and nail formation.  Essential component of keratin intermediate filaments in the companion layer of the hair follicle.
What are the official names of this protein?
Keratin, type II cytoskeletal 75, Cytokeratin-75, CK-75, Keratin-6 hair follicle, hK6hf, Keratin-75, K75, Type II keratin-K6hf, Type-II keratin Kb18.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: CP2K1_ONCMY
Sequence: MSLIEDILQTSSTVTLLGTVLFLLVLYLRSSGSSSEEQGKEPPGPRPLPLLGNMLQLDLKKPYCTLCELSKKYGSIFTVHFGPKKVVVLAGYKTVKQALVNQAEDFGDRDITPVFYDFNQGHGILFANGDSWKEMRRFALTNLRDFGMGKKGSEEKILEEIPYLIEVFEKHEGKAFDTTQSVLYAVSNIISAIVYGSRFEYTDPLFTGMADRAKESIHLTGSASIQMYNMFPWLGPWINNLTRLKKNIADMKMEVIELVRGLKETLNPHMCRGFVDSFLVRKQTLEESGHMDSFYHDDNLVFSVGNLFSAGTDTTGTTLRWGLLLMTKYPHIQDQVQEEISRVIGSRQTLVEDRKNLPYTDAVIHETQRLANIVPMSVPHTTSRDVTFQGYFIKKGTSVIPLLTSVLQDDSEWESPNTFNPSHFLDEQGGFVKRDAFMAFSAGRRVCLGEGLARMELFLFFTSLLQRFRFSPPPGVTEDDLDLTPLLGFTLNPSPHQLCAVSRV
What are the official names of this protein?
Cytochrome P450 2K1, CYPIIK1, Cytochrome P450 LMC2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: RAC1_LOTJA
Sequence: MSASRFIKCVTVGDGAVGKTCLLISYTSNTFPTDYVPTVFDNFSANVVVDGSTVNLGLWDTAGQEDYNRLRPLSYRGADVFILAFSLISKASYENIAKKWIPELRHYAPGVPIILVGTKLDLRDDKHFLADHPGAVPITTAQGEELRKLIGAPAYIECSSKTQQNVKAVFDAAIKVVLQPPKQKKKKREAQKSCSIL
What is the function of this protein?
Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation.
What are the official names of this protein?
Rac-like GTP-binding protein RAC1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with the membrane when activated.
Protein: Y2794_SHESA
Sequence: MQYPVDTHTHTLASTHAYSTIHDYLAVAKQKGIRLFATTDHGPAMADAPHFWHFVNLRVLPRMVDGVGILRGIEANIKNREGEIDYFGDYLSQLDIVLAGFHEPVFPPSDKATHTEAMINAIKSGKVDIITHPGNPAYPIDIEAVAAAAAEYGVALEINNSSFEVSRKGSEANCTAIAKAAKELGATLVMGSDSHVAFSLGGFDRALSIIEAVDYPKDKLLNRSPMALLNFLTQRGHQSVADLMPLFSDDIA
What are the official names of this protein?
Probable phosphatase Shewana3_2794.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: MCRA_METJA
Sequence: MDAEKRLFLKALKEKFEEDPREKYTKFYVFGGWRQSARKREFVEAAQKLIEKRGGIPFYNPDIGVPLGQRKLMPYKVSNTDAIVEGDDLHFMNNAAMQQFWDDIRRTVIVGMDTAHAVLEKRLGVEVTPETINEYMETINHALPGGAVVQEHMVEVHPALVWDCYAKIFTGDDELADEIDKRFLIDINKLFPEEQAEQIKKAIGKRTYQVSRVPTLVGRVCDGGTIARWSAMQIGMSFITAYKLCAGEAAIADFSYAAKHADVIQMASFLPARRARGPNEPGGIFFGVLADIVQTSRVSDDPVEQSLEVVAAGAMLYDQIWLGGYMSGGVGFTQYATATYTDDILDDFSYYGYDYITKKYGGCNSVKPTMDVVEDIATEVTLYGLEQYDTFPALLEDHFGGSQRAGVTAAAAGITTALATGNSNAGVNGWYLSQILHKEYHSRLGFYGYDLQDQCGAANSLSFRNDEGSPLELRGPNYPNYAMNVGHQGEYAGITQAAHSARGDAFALNPLIKVAFADPSLVFDFTHPRKEFARGALREFEPAGERDPIIPAH
What is the function of this protein?
Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2-(methylthio)ethanesulfonate) using coenzyme B (CoB or 7-mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB).  This is the final step in methanogenesis.
What are the official names of this protein?
Methyl-coenzyme M reductase I subunit alpha, MCR I alpha, Coenzyme-B sulfoethylthiotransferase alpha.
What is the protein family that this protein belongs to?
Belongs to the methyl-coenzyme M reductase alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA_TROWT
Sequence: MSKQPIITSEEVRGVIRNLLDSTLSAAREANEFEVGRVVDAADGVAHIEGLPALMASELVEFSNGTFGVTLNLDEDLAGVVVLGEFDGIVEGMDVRSTGRVLSIPVGDAFLGRVVDPLGRPVDGLGEVPHETYRELELQAAGVMQRRSVHEPIQTGIKAIDTMIPIGRGQRQLIIGDRQTGKTTIAIDTIINQKDNWSDPEKRVFCIYVAIGQKGSTIAGVKRVLEEAGCMEYTTIVATPASDPAGFKYIAPYSGSAIGQHWMYQGRHVLIVFDDLSKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDEMGGGSMTGLPIIETKANDISAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGDAQIKSIKKVSGMLKLELAQYRALEAFSMFASDLDAVSRRQLDRGARLSELLRQQQQSPYPVEDQVVSIWVGSNGYIDDIPLSDVLDFERDLLEYLRNRTSILDDLRTCGDLTDALLERLKEAVESFKNKVYFMRVDEREKDPLEDENIGQEELVRSRRAN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TRMB_STRPG
Sequence: MRVRKRKGAEEHLANNPHYVILNPEDAKGRWHDVFGNDRPIHIEVGSGKGGFITGMALKNPDINYIGIDIQLSVLSYALDKVLASEVPNVKLLRVDGSSLTNYFEDGEVDMMYLNFSDPWPKTKHEKRRLTYKDFLDTYKRILPEHGEIHFKTDNRGLFEYSLASFSQYGMTLRQIWLDLHASNYEGNVMTEYEEKFSNKGQVIYRVEANF
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RS16_DESAL
Sequence: MAVKIRLARHGAKKRPFYRIVVTDSESPRDGRFIEIVGTYNPVAEPAQIDLKDERIKHWMESGALPTHTVRNILKNQGFFSEAPQEA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: PURA_PLACH
Sequence: MNIFEHNIKNVDKGNVVAIVGTQWGDEGKGKIIDMLSKYSNITCRFNGGGNAGHTICVGNKKHALHLLPCGVLYENNVNVLGNCMVIHLKTLMKEINNLGNNILDRIYISEKAHILFDIHQEIDAMQETRKSKDGNAIGTTKKGIGPCYSTKASRIGIRMGSLRNFENFKKLYTKLIDNLMELYNIKDYNKEEELNEFYTYHQILKDKIINIMLYINKSIDAKKYILIEGANAAMLDIDLGTYPFVTSSSTTGGVFSGLGIHHKKLNLVVGVVKSYLTRVGSGPFLTEQCNEIGDYLTKKGFEYGTTTNRPRRCGWLDLPMLYYVKYINCIDIINLTKLDVLSGLKEIYICIDYKNKTTGELLEKGSYPLEEEQLREYEPVYEKFEGWDEDITNCLEFDQLPEKAKKYVLAIESYIKTPIVWIGVGPTRDHTITRKFD
What is the function of this protein?
Plays an important role in the salvage pathway for purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPP3_ASPNC
Sequence: MTTLDSILAGRYPAKAHARRVAERLQVGGSGRNGIIYLEAQKTRLIEDNDEAMHFRQRRPFFYLSGCPLPDSSLIYNIASDKLTLFIPPIDPEDVIWSGLPMSVAEALRLYDVDQVLHTTDVNATLASIASDGNGKSVAFAIEGQITEGIKFDGFLETNTSVLKGAIDSTRVVKDEYEIALLRKANDISAKAHIAAIEASKTATNEREIEAAFLATCIANGARDQAYHPIVACGQNGATLHYGRNDDDLVDPVTKAGKSSVLIDAGAEYRTYCADITRVFPLGGRFTSETQEIYKIVLQMQLEAIAMLKENVQWEDVHAHAHRIAIKGLLKLGILRGSEDELFEKRISVAFFPHGLGHYLGMDTHDTGGNPNYADKDTMFKYLRVRGRLPAGSVITVEPGIYFCRFIIEPYLTSPETSKYIDTNVLEKYWNVGGVRIEDNVHVTQQGYENLTTAPKAIEEVEVLAT
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase pepP, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: LAMP5_MOUSE
Sequence: MDLRVRTLLGGDRLRILLMFFHVMVQTVAEQEVENLSGLSTNPEKDIFVVRENGTTCLMAEFAAKFIVPYDVWASNYVDLITEQAEISLTRGAEVKGHCGHNESELEVFWVDHAYTLRMLFVKESHNTSKGPEATWNLNKVHFVYDSSEKTHFKAPVKVNKYIASSHHLSALVTPAGMSYECQAQQTISLASSDPQKTVTMILSAVHIQPFDIISDFVFSEEHKCPVDEQEQLEETLPLILGLILGLVIVITLVIYHIHHKMTANQVQIPRDRSQYKHMG
What is the function of this protein?
Plays a role in short-term synaptic plasticity in a subset of GABAergic neurons in the brain.
What are the official names of this protein?
Lysosome-associated membrane glycoprotein 5, Brain and dendritic cell-associated LAMP, Brain-associated LAMP-like protein, BAD-LAMP, Lysosome-associated membrane protein 5, LAMP-5.
What is the protein family that this protein belongs to?
Belongs to the LAMP family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein. Cell projection, growth cone membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Recycling endosome. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Note=Recycles from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane (PubMed:17215451). Colocalizes with UNC93B1 in large endosomal intracellular vesicles (By similarity). Accumulates in the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) before its disappearance upon activation by CpG dinucleotides (By similarity). Associates with cortical membranes (By similarity). Localizes mostly in cytoplasmic vesicles of neuronal cell body (PubMed:17215451). Localizes to synaptic vesicles in a subset of GABAergic neurons (PubMed:27272053).
Protein: UBIG_CAUSK
Sequence: MTQSASTAPSWSIDPADVARFSAIAAEWWDPRGKFAPLHVFNPCRLSFIREQALARFERDGNGRTPFEGLRLLDIGCGGGLLSEPMARLGFTVTAVDASEKNIKTAATHAAEQGLEIGYRPATAEQLLAEGAGPFDVVLTMEVVEHVADPGEFLRTCAKLLAPGGLMIVATLNRTLKALALAKIGAEYVLRWVPPGTHDWKQFLKPDELRAFLAGEPVDVHGPFGVAYNPLTGRWSRSADCDINYMMTVTKD
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: RECO_LACPL
Sequence: MVTNFNGILLFRRDYRERDMLIKFLTAEYGKKMFFIRGARRRGFKMAAELLPFTMGEYVGDLRDQGLSYINSVKSVQYLEHISQDIALNAYATYVMNLMDVAFPDNQPVGRWYQQLTSALQLIDQDVAPALVANVVEIQLLQPFGVAPELRWCTVCGRSDLPLDYSESYGGLLCQQHWHLDPHRLHASPAAIFYLRQFSVLDLAKVHSIKVKPRTAAELRRILDEIYQNSVGVRLKSKRFIDQMGSWYQPLAPRKNED
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: CYB_PARDE
Sequence: MAGIPHDHYEPKTGFERWLHRRLPIVSLVYDTLMIPTPKNLNWWWIWGIVLAFCLVLQIATGIVLVMHYTPHVDLAFASVEHIMRDVNGGYMLRYLHANGASLFFLAVYIHIFRGLYYGSYKAPREVTWIVGMLIYLMMMGTAFMGYVLPWGQMSFWGATVITGLFGAIPGVGEAIQTWLLGGPAVDNPTLNRFFSLHYLLPFVIAALVVVHIWAFHTTGNNNPTGVEVRRGSKEEAKKDTLPFWPYFVIKDLFALAVVLVVFFAIVGFMPNYLGHPDNYIEANPLVTPAHIVPEWYFLPFYAILRAFTADVWVVMLVNWLSFGIIDAKFFGVIAMFGAILVMALVPWLDTSRVRSGQYRPLFKWWFWLLAVDFVVLMWVGAMPAEGIYPYIALAGSAYWFAYFLIILPLLGIIEKPDAMPQTIEEDFNAHYGPETHPAE
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Cytochrome b.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SELW_SHEEP
Sequence: MAVVVRVVYCGAUGYKPKYLQLKKKLEDEFPSRLDICGEGTPQVTGFFEVFVAGKLVHSKKGGDGYVDTESKFLKLVAAIKAALAQA
What is the function of this protein?
Plays a role as a glutathione (GSH)-dependent antioxidant.  May be involved in a redox-related process.  May play a role in the myopathies of selenium deficiency (By similarity).
What are the official names of this protein?
Selenoprotein W, SelW.
What is the protein family that this protein belongs to?
Belongs to the SelWTH family. Selenoprotein W subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECY_ORYSJ
Sequence: MAAMATPQQCWLPTRARAPPPPPPRAPSSASPVSGAPASLRFRGRRAASASASAARRRRGASLPCSPRCALETAGPGFDPLGLYNDGPSRNDTQSPLSNFFGVLSPVFGSSSGGRKEKSYGRGAAAAIEDSSIDIGDFFKGPLPGKFLKLLGYLALSRLGIYIPLGGVNRDAFAGNLDQNSLLGTLDSFSGGGIGRLGICSLGIVPFINAQIVFQLLAQLYPKLQDLQKKEGEAGRKKVLQYTRYASVGFAIVQAIGQVLFLRPYVNDFSTEWVLTSVTLLTLGSVFTTFIGERISDLKLGNGTSLLIFTSIISYLPASFGRTVAQAFQDGNYVGLLTIILSFLFLVLGIVYVQEAERKIPLNYASRYSSRSGGLQRSAYLPFKVNSSGVMPIIFSTSSLALPGTLARFTGLEFLKKAAISLNPGGALYIPTNVLLIAFFNYYYTFLQLDPDDLSEQLKRQGASIPLVRPGKSTAAFIKTVLSNISVLGSAFLAVLAAGPSVVEQITHLTAFRGFAGTSVLILVGCATDTARKVQAEIISQKYKNIEFYDVNRFDQ
What is the function of this protein?
The central subunit of the protein translocation channel SecYE.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug (By similarity).
What are the official names of this protein?
Preprotein translocase subunit SECY, chloroplastic, CpSecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: HMUV_BORPA
Sequence: MTLQARNLTLARGGAPILTDVSLTLAPGTLVGLLGANGAGKSTLLAALAGELAPRSGQVYLGDADLATLNARQLARRRAVLPQKPSLSFDLGVSDVVGMGAYPFPELDPAAVRQLVRDALEQASVTHLAQRRYPQLSGGEQQRVQFARVLAQCHAMHAPGQTRYLMLDEPISNLDPRHQMELLATARALAHEAGMGVLVIVHDINQAARWCDTLALLADGRLAALGPPADVLTPDHMRRVYGIEADVLAHPTLPGRLLVLAR
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RLMD_THIDA
Sequence: MNPVVDILSLDHEGHGVARLDGKVTFVDGALAGERAEIAIFRKHAKYNSANAVAILAPSAQRAEPRCRYFGRCGGCSMQHLEPSAQVAAKQRVLEENLARIGKVRPSVLLPALHGPSWGYRGRARLSVRRVEKKGGVLVGFHEKRSSFIADMASCEVLAPGVSALIQPLRELIGRLSNADRIPQIEVAAGEHVIVLVFRLLEPWNDDDAAHVRAFADAHHVQVWEQRKGPETARPFWPDIAPELSYGLPEFGLVMPFRPTEFTQVNSAINRALVSRALRLLDPRPGERIADLFCGLGNFTLPIAHRGADVLGIEGSTELVARARENALRNALPHARFEVDNLFEMTPEKFAALGPFDKLLIDPPRSGAIEVVKSLPEAGAPRRIVYVSCDPATLARDAEVLVHVKGYRLEAAGVANMFPHTAHVESIALFER
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD, 23S rRNA(m5U1939)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
Protein: PA21_DABRR
Sequence: NLFQFGEMILEKTGKEA
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 1, PLA21, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MTAP_NITMS
Sequence: MEKDVEIGIFGGTGIYDSGLLEDAKEVDIDTPYGKPSDTITVGTFKGRKIAFLPRHGKKHTIPPHMINFKANIWAFKELGVTRIIAPSAVGSLKEELAPGHFVLPTQFLDFTKSRDGSFSEDGRVIHISVADPFCPELQSSITEVTDSLDMNIHKDCTYVCIEGPRFSTKAESKFYRTTGADIIGMTLVPECQLAREAQICYASISTVTDYDVWAEKPVTAKEVLETLSKNVEGTKKILTELIEKIPKDRSCSCAKALEEAEF
What is the function of this protein?
Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate.  Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis.  Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine.  Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
What are the official names of this protein?
S-methyl-5'-thioadenosine phosphorylase, 5'-methylthioadenosine phosphorylase, MTA phosphorylase, MTAP.
What is the protein family that this protein belongs to?
Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
Protein: MDH_KLEP3
Sequence: MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTDVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQIAKTCPQACIGVITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAELKGKSATEVEVPVIGGHSGVTILPLLSQIPGVSFSDQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVRAMQGEKGVVECAYVEGDGHYARFFSQPLLLGKNGVEERQSIGKLSAFEQQALEGMLDTLKKDIALGEDFVNK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.