PharMolix/UniProtQA huggingface dataset:
Protein: SYC_PECCP
Sequence: MLKIFNTLSRQKEEFKPIHAGQVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRYLGYSLKYVRNVTDIDDKIIKRAAENGETSDQLTTRMIAEMHADFDALNILRPDAEPRATHHITDIIEMVETLIARRHAYVASNGDVMFSVDTAPGYGVLSRQDLDQLQAGARVEITEVKRNPMDFVLWKMSKPGEPHWSSPWGEGRPGWHIECSAMNCKQLGEHFDIHGGGSDLMFPHHENEIAQSSCAHDGPYVNYWMHSGMVMVDREKMSKSLNNFFTVRDVLAYYDPETVRYFLMSGHYRSQLNYSEDNLKQARAALERLYTALRGTDPDAAAQGGDEFEGRFREAMDDDFNTPEAYSVLFDMAREVNRLKTEDAQAANQLASALRKLSGVLGLLEQDPEQFLQNGAQVDNDEVKEIEALIQQRKDARAAKDWALADQARDRLNEMGIVLEDGPQGTIWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXP24_ARATH
Sequence: MELLKRKLYAKILMMVMVIWIAPMTNGHDHASHVPGGRPGAHPSHGAHPAHGAHPSHGAHPSHGAHPSHGAHPSHGALPSHGGQVPHSGWGHGRATFYGDINGGETQQGACGYGDLHKQGYGLETAALSTALFNNGSRCGACYEIMCEHAPQWCLPGSIKITATNFCPPDFTKPNDNWCNPPQKHFDLSQPMFLKIAKYKAGVVPVKFRRVPCAKIGGVKFEIKGNPHFLMILPYNVGGAGAVRAMQIKGTRTQWIAMKKNWGQIWSTGVVLTGQCLSFRLTTSDGVMKEFIDVTPPDWKCNGQSFDGKVNF
What is the function of this protein?
Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans.  No enzymatic activity has been found (By similarity).
What are the official names of this protein?
Expansin-A24, AtEXPA24, Alpha-expansin-24, At-EXP24, AtEx24, Ath-ExpAlpha-1.19.
What is the protein family that this protein belongs to?
Belongs to the expansin family. Expansin A subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Peripheral membrane protein.
Protein: ORF23_TTVV6
Sequence: MPWRPPAHSVPGREGQFYAATFHAHAAFCGCGGFIEHLNSIHPRFLGAGGPPPPPPALRRALPAPEGPGGPPQHAPPNPPPEGDHQPPRRGGGAGGAGDGHAGDGDAAEEYGPEDLDLLFAAAAEDDMLSTTRARSPPTRYPSPVRSLESYKSVTRQGSDRKQFFTSGTKDVDCLQKEVLKECRNTHQMMKIFRQVLQSAQLSTPDPRAWPESKEAPTLFSGLSKTAKTRRRVKKKPLSSKNKHTKKKKRSYSSSSPSSKDNTSESSNEDSESCSETYSN
What are the official names of this protein?
Probable protein VP2, ORF2/3 protein.
Protein: SCNM1_DANRE
Sequence: MSFKREGDDQSQLNILKKRRVSDLLSNFIPDDEATLMKNGRYSCLVCSHRPVFDTVDMLVVHRKGKRHLEGMKWFYGKKNQLRREIDKRRHQDYVKAEDDRQEPSSSAPLLTQTRKITHHALLRTVPYSSCHKKASERSESSSKEHRNDLANSHLSMRTESNDSRTTVHQGPSEVKGEAKKKKKGASTLSSSVCEPLTEQRRRELDHYLKLKSSGWLQDRSGKWVKDENVEFDSDEEEPTLLPPCSESS
What is the function of this protein?
As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Sodium channel modifier 1.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle.
Protein: 2A5B_MOUSE
Sequence: METKLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQELTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGCTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYELEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWRGLEELRLRRLQGTQGAKEAPVPRPTPQVAASGGQS
What is the function of this protein?
As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation.  The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform, PP2A B subunit isoform B'-beta, PP2A B subunit isoform B56-beta, PP2A B subunit isoform PR61-beta, PP2A B subunit isoform R5-beta.
What is the protein family that this protein belongs to?
Belongs to the phosphatase 2A regulatory subunit B56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5694_ARATH
Sequence: MATRFKHQFSISLALTFFFFFTKTFSFTENEELGNLLRFKASFDDPKGSLSGWFNTSSSHHCNWTGITCTRAPTLYVSSINLQSLNLSGEISDSICDLPYLTHLDLSLNFFNQPIPLQLSRCVTLETLNLSSNLIWGTIPDQISEFSSLKVIDFSSNHVEGMIPEDLGLLFNLQVLNLGSNLLTGIVPPAIGKLSELVVLDLSENSYLVSEIPSFLGKLDKLEQLLLHRSGFHGEIPTSFVGLTSLRTLDLSLNNLSGEIPRSLGPSLKNLVSLDVSQNKLSGSFPSGICSGKRLINLSLHSNFFEGSLPNSIGECLSLERLQVQNNGFSGEFPVVLWKLPRIKIIRADNNRFTGQVPESVSLASALEQVEIVNNSFSGEIPHGLGLVKSLYKFSASQNRFSGELPPNFCDSPVLSIVNISHNRLLGKIPELKNCKKLVSLSLAGNAFTGEIPPSLADLHVLTYLDLSDNSLTGLIPQGLQNLKLALFNVSFNGLSGEVPHSLVSGLPASFLQGNPELCGPGLPNSCSSDRSNFHKKGGKALVLSLICLALAIATFLAVLYRYSRKKVQFKSTWRSEFYYPFKLTEHELMKVVNESCPSGSEVYVLSLSSGELLAVKKLVNSKNISSKSLKAQVRTIAKIRHKNITRILGFCFKDEMIFLIYEFTQNGSLHDMLSRAGDQLPWSIRLKIALGVAQALAYISKDYVPHLLHRNLKSANIFLDKDFEPKLSDFALDHIVGETAFQSLVHANTNSCYTAPENHYSKKATEDMDVYSFGVVLLELVTGQSAEKAEEGSSGESLDIVKQVRRKINLTDGAAQVLDQKILSDSCQSDMRKTLDIALDCTAVAAEKRPSLVKVIKLLEGISSSVSPVSA
What are the official names of this protein?
Probably inactive leucine-rich repeat receptor-like protein kinase At5g06940.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: MNMG_GLOVI
Sequence: MSCLPDWLAAGCRDGDAASHPTIRLRFRTATVHYLAEFDVVVVGAGHSGCEAALAAARLGCRTLLVTMNLDTIAWQPCNPAVGGPAKSQLVHEVDALGGEMAKITDRTYLQKRVLNSSRGPAVWALRAQTDKREYARELKQVLEATPNLTLRQGQITDIHLGPHDEICGVGTFFDVHFACRAVILTTGTFLGGRIWIGRKSMSAGRAGEFAAEGLTATLERLGFETGRLKTGTPARVDRRTVDFGVMEVQPPDPELRWFSFDPRAWVEREQLNCYLTRTTAATHQVIRDHLHLSPMYSGDIEARGPRYCPSIEDKIVRFADKESHQIFIEPEGRDTPELYVQGFSTSLPETVQIAMLRTLPGLEACAVLRPAYAVEYDYLPATQCYATLMTKRVEGLFCAGQINGTTGYEEAAAQGIVAGINAARLVRGEALVILPREGSYIGTLIDDLVTKEIREPYRMLTSRSEYRLVLRSDNADRRLTPLGREIGLVDDERWGLYQKKIAAITCERQRLETTRLNARDLPVHLAAKPGSITLADLLRRPGLHYGDLESLNQGVLLDAQVREGVEIEVKYSGYIERQNEQIERVSAQHARVIPADLDYERLSTLSKESREKLNRIRPRTIGQAGRIGGVNPADVSALLVYLELAQAGRLTPAAP
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_BRUA1
Sequence: MNMTKTAMLIALMTVMFMSIGYLLGGGGGMMIALVIAVAMNLFGYWNSDKMVLRMYNAQEVDERSAPEYYRMVSGLAANAGLPMPKVYIIHEDQPNAFATGRNPENAAVAATTGLLNRLSPEEVAGVMAHELAHVQNRDTLTMTIVATLAGAISMLGNFAFFLGGNRENGNGVMGVVGTLLAMIVAPFGAMIVQMAVSRTREYAADKRGAEICGNPLWLSSALGRIARGAKVIPNEEAEHNPATAHMFIINPLSGRGADNLFSTHPDTDNRIAALEQMAAEMGIRSAAMTARAAAPSQNSGPWGQRSDNAGGNSNGGSRYRGPWS
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: 3DHQ_SCLS1
Sequence: MPIKKILLLNGPNLNLLGTREPHIYGYDTLASIESSLSTYLSSLTPSVELLTFQSNWEGALIDRIHEARTDGTDAIVINPAAFTHYSVALRDALTGVDIPFVEVHISNVHKREEFRHKSFLSDKAEAVICGLGVFGYRAAVEWCVGYLKERPKL
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase, cDHQase, 3-dehydroquinate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: MYG_CHICK
Sequence: MGLSDQEWQQVLTIWGKVEADIAGHGHEVLMRLFHDHPETLDRFDKFKGLKTPDQMKGSEDLKKHGATVLTQLGKILKQKGNHESELKPLAQTHATKHKIPVKYLEFISEVIIKVIAEKHAADFGADSQAAMKKALELFRNDMASKYKEFGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: CTND2_MOUSE
Sequence: MFARKQSGAAPFGAMPVPDQPPSASEKNSSLSPGLNTSNGDGSETETTSAILASVKEQELQFERLTRELEAERQIVASQLERCKLGSETGSMSSISSAGEQFHWQTQDGQKDIEDELTTGLELVDSCIRSLQESGILDPQDYSTSERPSLLSQSALQLNSKPEGSFQYPASYHSNQTLALGDTAPSQLPARSTQARAAGQSFSQGTTGRAGHLAGSEPAPPPPPPREPFAPSLGSAFHLPDAPPAAAALYYSSSTLPAPPRGGSPLTTTQGGSPTKLQRGGSAPEGAAYAAPRGSSPKQSPSRLAKSYSTSSPINIVVSSAGLSPIRVTSPPTVQSTISSSPIHQLSSTIGTYATLSPTKRLVHASEQYSKHSQELYATATLQRPGSLAAGSRASYSSQHGHLAPELRALQSPEHHIDPIYEDRVYQKPPMRSLSQSQGDPLPPAHTGTFRTSTAPSSPGVDSVPLQRTGSQHGPQNAAAATFQRASYAAGPASNYADPYRQLQYCASVDSPYSKSGPALPPEGTLARSPSIDSIQKDPREFGWRDPELPEVIQMLQHQFPSVQSNAAAYLQHLCFGDNKIKAEIRRQGGIQLLVDLLDHRMTEVHRSACGALRNLVYGKANDDNKIALKNCGGIPALVRLLRKTTDLEIRELVTGVLWNLSSCDALKMPIIQDALAVLTNAVIIPHSGWENSPLQDDRKIQLHSSQVLRNATGCLRNVSSAGEEARRRMRECDGLTDALLYVIQSALGSSEIDSKTVENCVCILRNLSYRLAAETSQGQHMGTDELDGLLCGETNGKDTESSGCWGKKKKKKKSQDQWDGVGPLPDCAEPPKGIQMLWHPSIVKPYLTLLSECSNPDTLEGAAGALQNLAAGSWKGWAEDVAGMAYALRSLPEGAPCLPQWSVYIRAAVRKEKGLPILVELLRIDNDRVVCAVATALRNMALDVRNKELIGKYAMRDLVHRLPGGNNSNNSGSKAMSDDTVTAVCCTLHEVITKNMENAKALRDAGGIEKLVGISKSKGDKHSPKVVKAASQVLNSMWQYRDLRSLYKKDGWSQYHFVASSSTIERDRQRPYSSSRTPSISPVRVSPNNRSASAPASPREMISLKERKTDYESAGNNATYHGTKGEHTSRKDTMTAQNTGVSTLYRNSYGAPAEDIKQNQVSTQPVPQEPSRKDYETYQPFPNSTRNYDESFFEDQVHHRPPASEYTMHLGLKSTGNYVDFYSAARPYSELNYETSHYPASPDSWV
What is the function of this protein?
Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:17993462) (PubMed:25807484).  Involved in the regulation of canonical Wnt signaling (By similarity).  It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (PubMed:20623542).  May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.  Functions as a transcriptional activator when bound to ZBTB33 (PubMed:15282317).
What are the official names of this protein?
Catenin delta-2, Neural plakophilin-related ARM-repeat protein, NPRAP, Neurojungin.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Nucleus. Cell junction, adherens junction. Cell projection, dendrite. Perikaryon.
Protein: AGRG7_HUMAN
Sequence: MASCRAWNLRVLVAVVCGLLTGIILGLGIWRIVIRIQRGKSTSSSSTPTEFCRNGGTWENGRCICTEEWKGLRCTIANFCENSTYMGFTFARIPVGRYGPSLQTCGKDTPNAGNPMAVRLCSLSLYGEIELQKVTIGNCNENLETLEKQVKDVTAPLNNISSEVQILTSDANKLTAENITSATRVVGQIFNTSRNASPEAKKVAIVTVSQLLDASEDAFQRVAATANDDALTTLIEQMETYSLSLGNQSVVEPNIAIQSANFSSENAVGPSNVRFSVQKGASSSLVSSSTFIHTNVDGLNPDAQTELQVLLNMTKNYTKTCGFVVYQNDKLFQSKTFTAKSDFSQKIISSKTDENEQDQSASVDMVFSPKYNQKEFQLYSYACVYWNLSAKDWDTYGCQKDKGTDGFLRCRCNHTTNFAVLMTFKKDYQYPKSLDILSNVGCALSVTGLALTVIFQIVTRKVRKTSVTWVLVNLCISMLIFNLLFVFGIENSNKNLQTSDGDINNIDFDNNDIPRTDTINIPNPMCTAIAALLHYFLLVTFTWNALSAAQLYYLLIRTMKPLPRHFILFISLIGWGVPAIVVAITVGVIYSQNGNNPQWELDYRQEKICWLAIPEPNGVIKSPLLWSFIVPVTIILISNVVMFITISIKVLWKNNQNLTSTKKVSSMKKIVSTLSVAVVFGITWILAYLMLVNDDSIRIVFSYIFCLFNTTQGLQIFILYTVRTKVFQSEASKVLMLLSSIGRRKSLPSVTRPRLRVKMYNFLRSLPTLHERFRLLETSPSTEEITLSESDNAKESI
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Adhesion G-protein coupled receptor G7, G-protein coupled receptor 128.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZN273_HUMAN
Sequence: MSSAPRGPPSVAPLPAGIGRSTAKTPGLPGSLEMGPLTFRDVAIEFSLEEWQCLDTSQQNLYRNVMLDNYRNLVFLGIAVSKPDLITCLEQGKEPCNMKRHAMVAKPPVVCSHFAQDLWPKQGLKDSFQKVILRRYGKYGHENLQLRKGCKSADEHKVHKRGYNGLNQCLTTTQSKIFQCDKYVKVLHKFSNSNIHKKRQTGKKPFKCKECGKSCCILSQLTQHKKTATRVNFYKCKTCGKAFNQFSNLTKHKIIHPEVNPYKCEECGKAFNQSLTLTKHKKIHTEEKPYKCEDCGKVFSVFSVLTKHKIIHTGTKPYNCEECGKGFSIFSTLTKHKIIHTGEKPYKCNECGKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNQSSTLTRHKIVHTGEKPYKCEECGKAFKRSTTLTKHKRIYTKEKPYKCEECGKAFSVFSTLTKHKIIHTGAKPYKCEECGSAFRAFSTLTEHKRVHTGEKPYKCNECGKAFNWSSTLTKHKRIHTGEKPYKCEECGKAFNRSSNLTRHKKIHTGEKPYKPKRCDSAFDNTPNFSRHKRNHMGEKS
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 273, Zinc finger protein HZF9.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ELTB_CLOPF
Sequence: MLSNNLNPMVFENAKEVFLISEDLKTPINITNSNSNLSDGLYVIDKGDGWILGEPSVVSSQILNPNETGTFSQSLTKSKEVSINVNFSVGFTSEFIQASVEYGFGITIGEQNTIERSVSTTAGPNEYVYYKVYATYRKYQAIRISHGNISDDGSIYKLTGIWLSKTSADSLGNIDQGSLIETGERCVLTVPSTDIEKEILDLAAATERLNLTDALNSNPAGNLYDWRSSNSYPWTQKLNLHLTITATGQKYRILASKIVDFNIYSNNFNNLVKLEQSLGDGVKDHYVDISLDAGQYVLVMKANSSYSGNYPYSILFQKF
What is the function of this protein?
This enterotoxin is responsible for many cases of a mild type of food poisoning.
What are the official names of this protein?
Heat-labile enterotoxin B chain.
Protein: DPO4_CLOPS
Sequence: MKENRKIIHIDMDAFYASIEQRDNPKYKGKPLIVGGDPNRRGVVATCSYEARKYGIHSAMPSLTAYKLCPKAIFIRPRMEVYKKVSRQVMNILNEYSNLVEPLSLDEAFVDVSKSKRCKGSATLIALEIKERIFKEVGLTASAGVSFNKFLAKMASDFRKPDGITVITEENSKDFIRKLPIGKFFGVGRVTKNKLNNIGVFKGEDLLGFSEKELIGILGDRGKILYEFARGIDNRQVNPYRIRKSIGKEITLREDIEDIEEMIEILDKIAERVSESLCLLNKKGKTVTLKVKFNDFKHITRSITLEHFLKEKKEIMECVKDLISIVDFKNKKVRLLGITISSLEENIIIEEREQLSFDV
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRDM5_MOUSE
Sequence: MLGMYVPDRFALKSSRVQDGMGLYTARRVRKGEKFGPFAGEKRMPEDLDENMDYRLMWEVRGSKGEVLYILDATNPRHSNWLRFVHEAPSQERKNLAAIQEGENIFYLAVDDIETDTELLIGYLDSDVEAEEEEQQALTMTKEGKVDHSKGQLAAGSKGHLGCEEDFACPQCESSFPSEEVLTEHLQSLHQKPTGEKEFKCENCGKKFPVRQALQRHFEQHRKACRGEARFVCKADSCGKRLKSKDALRRHQENVHTGDPKRKLICSVCNRKCTSVSSLQEHRKIHEIFDCQECMKKFISANQLKRHMITHSEKRPYNCEICNKSFKRLDQVGAHKVIHSEDKPYQCKLCGKGFAHRNVYKNHKKTHSEERPFQCDACKALFRTPFSLQRHLLIHNSERTFKCHHCDATFKRKDTLNVHVQVVHERHKKYRCELCNKAFVTPSVLRSHKKTHTGEKEKVCPYCGQKFASSGTLRVHIRSHTGERPYQCPYCEKGFSKNDGLKMHIRTHTREKPYQCSECSKAFSQKRGLDEHKRTHTGEKPFQCDVCDLAFSLKKMLIRHKMTHNPNRPMAECHFCHKKFTRNDYLKVHMDNIHGVADS
What is the function of this protein?
Sequence-specific DNA-binding transcription factor.  Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1.  Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes (By similarity).  May regulate the expression of proteins involved in extracellular matrix development and maintenance, connective tissue components and molecules regulating cell migration and adhesion.  May cause G2/M arrest and apoptosis in cancer cells (By similarity).
What are the official names of this protein?
PR domain zinc finger protein 5, PR domain-containing protein 5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS4_SYNP2
Sequence: MEVIPAIDLLGGQCVRLYQGDYQQAQVFNNDPVQVARTWAEQGATRLHVVDLDGAKQGESVNLGAIAKIAAAIDIPVQVGGGLRTVESVAQLFDVGVERAILGTAAVDNPDLVTELCAKYPGRIAVGIDARDGKVATKGWLETSAVLATDLAKQMATQGVAAIIYTDIHRDGTMAGPNLEALRELAATIEIPVIASGGVSSLADLVNLVALEGIGVTGAIVGRAIYTGDINLAEAVKAVGPQRLQDVFPDDGTAIA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPLA_SERP5
Sequence: MSNLRLLISDSYDPWFNLAVEECIFREMTTQKILFLWRNAETVVIGQSQNPWKECNTRRMEQDGIRLARRSSGGGAVFHDLGNSCFTFMAGKPGYDKTVSTGIILQALAQLGITATASGRNDLVIDTAEGVRKISGSAYRETQDRGFHHGTLLLNADLNRLADYLNPDPKKLQAKGITSVRSRVANLAEFKADISHHQVCDAITQAFFDHYGEMAKAEIISPDVYPDLPDFAAQFAKQSSWQWNFGKAPAFSHLLNERFVWGGVDIFFDVEKGAICRAQIFTDSLSPAPLQRLAEMLVGCTYRSEALANCCDALIVQYPEQAAELTELRQWLLETIK
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Lipoate-protein ligase A, Lipoate--protein ligase.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELO_TOLAT
Sequence: MAFLHFDNRFIRELPGDPLTLNQPRQVHAAFWSAVTPAPVPQPQLIASSAEVAALLGISLAELQQPAWVAALSGNGLLDGMSPFATCYGGHQFGNWAGQLGDGRAISLGELIHNDLRWELQLKGAGVTPYSRRGDGKAVLRSSIREFLCSEAMFHLGVPTTRALSLVLTGEQIWRDMFYDGNPQQEPGAIVCRVAPSFIRFGHFQLPAMRGESDLLNQLIDFTIDRDFPHLSAQPATVRRGVWFSEVCITTAKLMVEWTRVGFVHGVMNTDNMSILGLTIDYGPYGWVDNFDLNWTPNTTDAEGLRYCFGRQPAIARWNLERLAEALGTVMTDHAILAQGIEMFDETFAQEMAAMLAAKLGWQQWLPEDSELVNRLFDLLQQAEVDMTLFFRRLALVDVSAPDLTVLADAFYRDDLFCQHQPAFTQWLTNYSQRVLSEGVLPAERAARMNQVNPVYVLRNYLAQQVIDAAEQGNYQPIAELLEVLRQPYTEQSGKEAYAQKRPDWARHKPGCSMLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: OPGC_ECO27
Sequence: MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
What is the function of this protein?
Necessary for the succinyl substitution of periplasmic glucans.  Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
What are the official names of this protein?
Glucans biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family. OpgC subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGBD5_MOUSE
Sequence: MAEGGGGSRRRAPALLEAARARYESLHISDDVFGESGPDSGGNPFYSTSAASRSSSAASSDDERERPAPPGTAPPSYAADPLELEEDETGGGWSAVLRDRPSPRFEDTGGPTRKMPPSASAVDFFQLFVPDNVLKNMVVQTNMYARKFQERFGSDGAWVEVTLAEMKAFLGYVISTSVSHCESVLSIWSGGFYSNRSLALVMSQARFEKILKYFHVVAFRSSQTTHGLYKVQPFLDSLQSGFDAAFRPSQTQVLHEPLIDEDPVFIATCTERELRKRKKRKFSLWVRQCSSTGFIIQIYVHLKEGGGPDGLDALKNKPQLHSMVARSLCRNAAGKNYIIFTGPSITSLNLFEEFEKQGIYCCGLLSSRKSDCTGLPPSMLTNPATPLARGQHQIRTKGNMSLICWYNKGHFRFLTNAYSPVQKGVIIKRRSGEIPCPLAVEAFAAHLSYICRYDDKYSKYFISHKPNKTWQQVFWFAISIAVNNAYILYKMSDAYHVKKYSRAQFGERLVRELLGLEDSSPAH
What is the function of this protein?
Transposase that mediates sequence-specific genomic rearrangements.
What are the official names of this protein?
PiggyBac transposable element-derived protein 5, PiggyBac transposase 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUB9_ARATH
Sequence: MAKTGVFDSDPTAIAKAKELKREMKKLLIKIDDEDDLGVQTIDQLQDALSALREATMRKMAKSSSLEMLETVSCPEEFRCPLSNELMRDPVVLASGQTYDKLFIQKWLSSGNRTCPKTQQVLPHTALTPNLLIREMISKWCKKNGLETKSQYHPNLVNEDETVTRSDREIFNSLLCKVSSSNLQDQKSAAKELRLLTRKGTEFRALFGESPDEITRLVNPLLHGSNPDEKLQEDVVTTLLNISIHDDSNKKLVCENPNVIPLLIDALRRGTVATRSNAAAAIFTLSALDSNKVLIGKSGILKPLIDLLEEGNPLAIKDVAAAIFTLCIAHENRSRAVRDGAVRVLGKKISNGLYVDELLAILAMLVTHWKAVEELGELGGVSWLLKITRESECKRNKENAIVILHTICFSDRTKWKEIKEEENAHGTITKLSREGTSRAQRKANGILDRLRKAMNLTHTA
What is the function of this protein?
Functions as an E3 ubiquitin ligase (By similarity).  May be involved in the abscisic acid-mediated signaling pathway, at least during germination.
What are the official names of this protein?
U-box domain-containing protein 9, Plant U-box protein 9, RING-type E3 ubiquitin transferase PUB9.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Note=Relocates from nucleus to plasma membrane when phosphorylated.
Protein: RNJ2_STAAR
Sequence: MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMFPEDEMLGIDIVIPDISYVLENKEKLKGIFLTHGHEHAIGAVSYVLEQLDAPVYGSKLTIALIKENMKARNIDKKVRYYTVNNDSIMRFKNVNISFFNTTHSIPDSLGVCIHTSYGAIVYTGEFKFDQSLHGHYAPDIKRMAEIGEEGVFVLISDSTEAEKPGYNTPENVIEHHMYDAFAKVRGRLIVSCYASNFIRIQQVLNIASKLNRKVSFLGRSLESSFNIARKMGYFDIPKDLLIPITEVDNYPKNEVIIIATGMQGEPVEALSQMAQHKHKIMNIEEGDSVFLAITASANMEVIIANTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMINIMKPEYFIPVQGEFKMQIAHAKLAAEAGVAPEKIFLVEKGDVINYNGKDMILNEKVNSGNILIDGIGIGDVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEDLLREAEEKVREIVEAGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI
What is the function of this protein?
An RNase that has 5'-3' exonuclease and possibly endoonuclease activity.  Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity).
What are the official names of this protein?
Ribonuclease J 2, RNase J2.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC036_HUMAN
Sequence: MQAETILEGLEAGLPQAVSSGLSLVPAPGLVLTCLSAPSGPGGMALEPPPTTLRKAFLAQSTLLESTLEGAPEWAAPHPEEQRRSPPACSQHTPPLPSTPTGPPPCSPGGNHPLCALSGRGGGRCSIPSLSSSSTFSLFSSGCWNPRVKLRVRKSQSQGRAGQLI
What are the official names of this protein?
Uncharacterized protein C3orf36.
Protein: LEPA_PSYA2
Sequence: MTALANIRNFSIIAHIDHGKSTLADRFIQMCGALQDREMQAQVLDSMDIERERGITIKAQSVTLYYDHPNGERYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTAVDQGLEVMAVLNKIDLPQVEPERVIQEIEDIIGIDAVDAPRVSAKSGLGVDKLLEALVEFIPAPTGDRDAPLQALIIDSWFDNYLGVVSLVRVRQGTIKKGDKLYIKSTKDAHLVGSIGVFTPKPLDTGILEAGEVGFIIAGIKDIAGAPVGDTITHASTPDVDCIPGFKQITPQVYAGMFPVESTDFEKFREALQKLQINDASLFFEPDTSDALGFGFRCGFLGMLHMEIIQERLEREYDLDLITTAPSVIYEIVKKDGSIIYVDNPSRLPEPNNIEEFREPIARCQILVPQDYLGNVMTLCIERRGVQVDMRFMGRQVQLIFDIPMGEVVMDFFDRLKSVSRGFASLDYNFERYQVDKLVKVDVLINGDKVDALAMIVHETQSRYRGNALVSKMKELIPRQMFDVAIQAAIGSQIIGRSTVKAMRKDVLAKCYGGDVSRKKKLLSKQKAGKKRMKQVGNVEIPQEAFLAVLQVD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.