PharMolix/UniProtQA huggingface dataset:
Protein: MNME_PSEA6
Sequence: MTVEQNTPDQDTIVAQATASGRGGVGIVRVSGSLAAKVAEQIIGHVPLIRNAQYVPFKSNTGEPLDQGIALFFKAPHSFTGEDVLELQGHGGQVVLDMLIKATLHVPNVRLARPGEFSERAYLNDKLDLAQAEAIADLIDASSEQAARGALRSLQGEFSTQINSLVELLTHLRIYVEAAIDFPDEEIDFLSDGKVQNDLKAITKQLSSVKSQARQGSLLREGMRVVIAGRPNAGKSSLLNALAGRDAAIVTAIAGTTRDVLKEHIHIDGMPLHIIDTAGLRDSSDEVERIGIERAWQEIEQADRVLFMLDSTETHENDPYKIWPEFMRRLPKNMGLTVIRNKADLSGENVGKVQYDDYPVFQLSASHKQGIEVLAEHLKECMGFHSSNEGQFIARRRHIDAIERAEEHLLLGKQQLEDNLAGELLAEELRLAQAYLSEITGEFSSDDLLGKIFSSFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLEA3_NIDPL
Sequence: MFTLKKTLLLLFFLGTISISLCKQARDADEDDGRKMTEEEVKRSIITMTREAKLPQLWKQIACRLYNTC
What is the function of this protein?
Antimicrobial peptide.  Has activity against Gram-positive and -negative bacteria, and fungi.  Has little hemolytic activity on red blood cells (By similarity).
What are the official names of this protein?
Pleurain-A3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Pleurain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYGB_NEIMB
Sequence: MMTQTLLIELLTEELPPKALNNLGNHFAASVAEGLEKAQLVDGAAEFTAYASPRRLAVQVKNVKAVQADQKIVKKGPAVANAMKDGAPTKALEGFARGAGAKIEDLTIVHDGKQDVYAYEYVQIGKPLGGLLEDIINQAVKKLPIPKVMRWGSSTFTFVRPVHGLVVLHGGDIVNVSVLGLQSGNKTLGHRFLSDGEITIENADSYAAQMREQGKVVASFAERKAAIQTVLEGQARRLNATAAADEALLDEVTALVEWPVVLEAGFEEHFLAVPQECLILTMQQNQKYFPLLDQNGKLMNRFLLVSNLQTEDPSHIIQGNERVLRARLSDAEFFYKQDQKATLESRLPKLTNVVYHNKIGSQAERIERLQSIAAHIAKALGADAAAAERAARLAKADLVTEMVGEFPELQGTMGKYYARLDGETEEITEAVEQHYQPRFAGDNLPEGKIAAAVALADKLETLVGIWGIGLIPTGDKDPYALRRAALGILRMLMQYGLDVNELIQTAFNSFPQGLLNEKTPSETADFMQARLAVLLQNDYPQDIVAAVLAKQPRRLDDLTAKLQAVAAFKQLPEAAALAAANKRVQNLLKKADAELGAVNESLLQQDEEKALFAAAQGLQPKIAAAVAEGNFQTALSELASVKPQVDAFFDGVMVMAEDAAVKQNRLNLLNRLAEQMNAVADIALLGE
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP4_ROT18
Sequence: MGSFIYKQLLTNSYTVELSDEIDAIGSEKTQNVTINPGPFAQTGYAPVEWGAGETNDSTTIEPVLDGPYQPTRFNPEIGYWILLAPETQGIVLETTNTTNKWFATILIEQDVVAESRTYTIFGKTESIQAENTSQTEWKFIDIIKTTQDGTYSQYGPLVLSTKLYGVMKYGGRLYAYIGHTPNATPGHYTIANYDTMEMSIFCEFYIMPRSQEAQCTEYINSGLPPIQNTRNIVPLSLSSRSIKYQKAQVNEDIIISKTSLWKEMQYNIDIIIRFKFNNSIIKSGGLGYKWLEIAFKPANYQYNYIRDGENITAHTTCSVNGVNEFSYNGGSLPTDFAISRYEVIKENSYVYVDYWDDSQAFRNMVYVRSLAANLNTVICNGGDYSFQVPVGQWPVMSGGAVSLQSAGVTLSTQFTDFVSLNSLRFRFSLAVESPPFSITRTRVSNLYGLPAANPNGGRDFYEILGRFSLISLVPSNDDYQTPIMNSVTVRQDLDRQLGELRDEFNALSQQIAMSQLIDLALLPLDMFSMFSGIKGSIDVARSMATKVMKKFRNSKLASSVSTLTDSLSDAASSLSRTSTIRSIGSSASAWTNISSQVDDVISSTSEISTQTSTISRRLRVKEIATQTEGMNFDDISAAVLKAKIDRSTQIDSNTLPDIVTEASEKFIPNRAYRVMDGDEVLEASTDGKFFAYKVETFDEVPFDVQKFADLVTDSPVISAIIDFKTLKNLNDNYGITKAQAFNLLRSDPRVLREFINQENPIIRNRIEQLILQCKL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: HELLS_MOUSE
Sequence: MAEQTEPAVITPAMLEEEEQLEAAGLEKERKMLEEAQKSWDRESTEIRYRRLQHLLEKSNIYSKFLLTKMEQQQLEEQKKKEKLEKKKRSLKLTEGKSLVDGNGEKPVMKKKRGREDESYNISEVMSKEEILSVAKKHKDNEDESSSTTSLCVEDIQKNKDSNSMIKDRLSQTVRQNSKFFFDPVRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGINGILADEMGLGKTVQCIATIALMIQRGVPGPFLVCGPLSTLPNWMAEFKRFTPEIPTLLYHGTREDRRKLVKNIHKRQGTLQIHPVVVTSFEIAMRDQNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSELWSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLKSDVALEVPPKREVVVYAPLCNKQEIFYTAIVNRTIANMFGSCEKETVELSPTGRPKRRSRKSINYSELDQFPSELEKLISQIQPEVNRERTVVEGNIPIESEVNLKLRNIMMLLRKCCNHPYMIEYPIDPVTQEFKIDEELVTNSGKFLILDRMLPELKKRGHKVLVFSQMTSMLDILMDYCHLRNFIFSRLDGSMSYSEREKNIYSFNTDPDVFLFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCHRIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLIIHKNHFKGGQSGLSQSKNFLDAKELMELLKSRDYEREVKGSREKVISDEDLELLLDRSDLIDQMKASRPIKGKTGIFKILENSEDSSAECLF
What is the function of this protein?
Plays an essential role in normal development and survival.  Involved in regulation of the expansion or survival of lymphoid cells.  Required for de novo or maintenance DNA methylation.  May control silencing of the imprinted CDKN1C gene through DNA methylation.  May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.
What are the official names of this protein?
Lymphocyte-specific helicase, Proliferation-associated SNF2-like protein.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
Protein: KDSA_SHEB8
Sequence: MSNKIINLGSIEIANDKPFVLFGGMNVLESRDLAMSIAETYAEVTQKLGIPYVFKASFDKANRSSINSYRGPGMEEGLKIFEEIKKTFNLPLITDVHEVHQCAPVAEVVDIIQLPAFLARQTDLVVAMAKTGTIINVKKPQFLAPHEMRHIITKFNEAGNDEIILCERGSSFGYNNLVVDMLGMDEMKQSGYPVIFDATHALQRPGGRADSAGGRRAQAAELARSGMALGLAGLFIEAHPDPDNAKCDGPCALPLHQLENYLKQMKAIDDLVKSFDPIDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOI2_STRAW
Sequence: MAPIPGSGLAKGLAVTLRTMTKKTVTAQYPDAQPELPPRSRGVIGLFEENCTVCMLCARECPDWCIYIDSHKETVPPAAPGGRERSRNVLDRFAIDFSLCMYCGICIEVCPFDALFWSPEFEYAETDIHELTHERDKLREWMWTVPAPPALDPAAEEPKEIAAARKTAEKLAAAQAAAAQTDAAQAEAAQAEAAAEAGSAAEGAPDAAPKPQEGEA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NHL6_ARATH
Sequence: MSQHQKIYPVQDPEAATARPTAPLVPRGSSRSEHGDPSKVPLNQRPQRFVPLAPPKKRRSCCCRCFCYTFCFLLLLVVAVGASIGILYLVFKPKLPDYSIDRLQLTRFALNQDSSLTTAFNVTITAKNPNEKIGIYYEDGSKITVWYMEHQLSNGSLPKFYQGHENTTVIYVEMTGQTQNASGLRTTLEEQQQRTGNIPLRIRVNQPVRVKFGKLKLFEVRFLVRCGVFVDSLATNNVIKIQSSSCKFRLRL
What is the function of this protein?
Plays an important role in the abiotic stresses-induced abscisic acid (ABA) signaling and biosynthesis.  Acts as positive regulator of ABA-mediated seed germination inhibition.  Functions downstream of ABF2/AREB1, ABF4/AREB2 and ABF3.
What are the official names of this protein?
NDR1/HIN1-like protein 6.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Cytoplasm, cytosol. Note=Moves from plasma membrane to cytosol under abiotic stress.
Protein: ASSY_BACP2
Sequence: MSQNKKVVLAYSGGLDTSVAVKWLQEQGYEVVACCLDVGEGKDLAFVQQKALQVGAVQSYMIDAKEEFAEEFALTALQAHTMYEGKYPLVSALSRPLIAKKLVEVAEKENAVAVAHGCTGKGNDQVRFEVSIKALNPDLEVLAPVREWKWSRDEEIDYAQKHGIPIPINLDSPYSIDQNLWGRSNECGILEDPWAAPPEGAYDLTTPLEKTPDTPEIIEITFEKGKPTAIDGIQYSLSDLILHLNEVAGQHGVGRIDHVENRLVGIKSREVYECPGAVTLLKAHKELEDLTLVKEVAHFKPIVEQKMAELIYNGLWFSPLKGALDAFLQETQQNVTGVVRVKLFKGHAIVEGRKSPYSLYDENLATYTKADEFDHDAAVGFINLWGLPTKVNSIVNKKEQVKA
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MA651_ARATH
Sequence: MAVTDTESPHLGEITCGTLLEKLQEIWDEVGESDDERDKLLLQIEQECLDVYKRKVEQAAKSRAELLQTLSDANAELSSLTMSLGDKSLVGIPDKSSGTIKEQLAAIAPALEQLWQQKEERVREFSDVQSQIQKICGDIAGGLSNEVPIVDESDLSLKKLDDFQSQLQELQKEKSDRLRKVLEFVSTVHDLCAVLGLDFLSTVTEVHPSLDEDTSVQSKSISNETLSRLAKTVLTLKDDKKQRLQKLQELATQLIDLWNLMDTPDEERELFDHVTCNISSSVDEVTVPGALARDLIEQAEVEVDRLDQLKASRMKEIAFKKQSELEEIYARAHVEVNPESARERIMSLIDSGNVEPTELLADMDSQISKAKEEAFSRKDILDRVEKWMSACEEESWLEDYNRDQNRYSASRGAHLNLKRAEKARILVSKIPAMVDTLVAKTRAWEEEHSMSFAYDGVPLLAMLDEYGMLRQEREEEKRRLREQKKVQEQPHVEQESAFSTRPSPARPVSAKKTVGPRANNGGANGTHNRRLSLNANQNGSRSTAKEAGRRETLNRPAAPTNYVAISKEEAASSPVSGAADHQVPASP
What is the function of this protein?
Microtubule-associated protein that bundle and stabilize adjacent microtubules (MT) of the cell cortex.  Enhances MT nucleation.  Can also bind to tubulin dimers and promotes their polymerization.  Confers MT resistance to the drug propyzamide and cold conditions.  Plays a role in the central spindle at anaphase to early cytokinesis but is not essential at the midline of the phragmoplast at later stages.  Represses metaphase spindle organization and the transition to anaphase in dephosphorylated active form.  Promotes the formation of a planar network of antiparallel microtubules.  May be involved in stomatal movement modulation by regulating the dynamic and arrangement of cortical MT.
What are the official names of this protein?
65-kDa microtubule-associated protein 1, AtMAP65-1.
What is the protein family that this protein belongs to?
Belongs to the MAP65/ASE1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Cytoplasm, cell cortex. Note=During interphase, binds cortical microtubules. In M-phase, locates to the preprophase band. Binds the preprophase band but does not accumulate at the prophase spindle microtubules that coexists within the same cell. In the metaphase and anaphase, localized to spindle. In the phragmoplast, concentrated at the midzone where vesicles guide by MT coalesce to form the cell plate. Present in MT cortical arrays. Concentrated in dots surrounding the nuclei.
Protein: Y1634_MYCTO
Sequence: MTETASETGSWRELLSRYLGTSIVLAGGVALYATNEFLTISLLPSTIADIGGSRLYAWVTTLYLVGSVVAATTVNTMLLRVGARSSYLMGLAVFGLASLVCAAAPSMQILVAGRTLQGIAGGLLAGLGYALINSTLPKSLWTRGSALVSAMWGVATLIGPATGGLFAQLGLWRWAFGVMTLLTALMAMLVPVALGAGGVGPGGETPVGSTHKVPVWSLLLMGAAALAISVAALPNYLVQTAGLLAAAALLVAVFVVVDWRIHAAVLPPSVFGSGPLKWIYLTMSVQMIAAMVDTYVPLFGQRLGHLTPVAAGFLGAALAVGWTVGEVASASLNSARVIGHVVAAAPLVMASGLALGAVTQRADAPVGIIALWALALLIIGTGIGIAWPHLTVRAMDSVADPAESSAAAAAINVVQLISGAFGAGLAGVVVNTAKGGEVAAARGLYMAFTVLAAAGVIASYQATHRDRRLPR
What is the function of this protein?
Could be involved in fluoroquinolones efflux.
What are the official names of this protein?
Probable multidrug-efflux transporter MT1670.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SAMH1_CHICK
Sequence: MGSPAAGWGAAPAKRARREGSAESSCGSPADRDPRLWDTERLCQHLSRNGVGEPGLLRRFRESGVTGAMLLDLPACALRITHACLPDERLKVLACLNQLRQTADIMKVFNDPVHGHIEIHPLLVRIIDTPQFQRLRYIKQLGGTYFVFPGASHNRFEHSLGVGYLAGCLVRELKERQPELDITQRDILCVEIAGLCHDLGHGPFSHMFDGRFIPLARQGLNWKHETASVEMFEHLITSNKLEEIMESYGLILEEDIAFIKEQIGGPIDETACEESWPYRGRPKEKSFLYEIVANKKNGIDVDKWDYFARDCHHLGIQNNFDYRRLIKFTRVCEAGNQKHICARDKEVGNLYDMFHTRNCLHRRAYQHKVGNIIEIMITEAFQKADCFFQIEGSKGKLYHISTAMEDMEAYTKLTDNIYLEILHSSRPELSEAREILHKIERRELYKFLGETQPEKVNEIPKDEYDGLAGDIANSKPEKDPPDVELTAEDFIVDVVNMDYGMKDQNPIDNVLFYCKADPSKAIKISKEQVSRLLPGTFSEQVIRVYCKRQDPIIVSAAKQYFVQWCIKRDFTKPQDGDVVAPHLTPLKQSWNNRSKTEYTTASEPSCKQKLSFNK
What is the function of this protein?
Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks.  Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells.  Functions during S phase at stalled DNA replication forks to promote the resection of gapped or reversed forks: acts by stimulating the exonuclease activity of MRE11, activating the ATR-CHK1 pathway and allowing the forks to restart replication.  Its ability to promote degradation of nascent DNA at stalled replication forks is required to prevent induction of type I interferons, thereby preventing chronic inflammation.  Ability to promote DNA end resection at stalled replication forks is independent of dNTPase activity.
What are the official names of this protein?
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, dNTPase.
What is the protein family that this protein belongs to?
Belongs to the SAMHD1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to sites of DNA double-strand breaks in response to DNA damage.
Protein: CYB_ERIBA
Sequence: MTNIRKTHPLIKIINSSFIDLPTPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFMETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFILPFVVLALAAVHLLFLHETGSNNPSGISSDSDKIPFHPYYTVKDILGALLLILVLMLLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIAPLLHTSKQRGMMFRPISQCLFWLLVADLLTLTWIGGQPVEHPYITIGQLASILYFAILLVFMPIASIIENNILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y137_ATV
Sequence: MASQKNSESLVGELVNQINELYLTNPNQVIKLAKKAGVENPTFLVKPPTKPTNELSFAKLNNIAETVEKLEKYGLPSLLRQYFMTVVKNPAVIDNVVETYYKIAKIIPKEVENKEPLVISEKEGFVSKSIPPVIKVS
What are the official names of this protein?
Uncharacterized protein ORF137.
Protein: RECF_PSECP
Sequence: MYLEHLSLTDFRSYAQVDLVLSPGVTVLVGYNGIGKTNLMEAIGYLATLSSHRVSSDGPLLRFGTERALVRARLVRNGQTTVLELEINAGRANRGRINRSNPVRARDLLGICQTVLFAPEDLALVKGDPSNRRRFLDELLASLVPHHAATRSDYDRVLKQRNALLKSARAGRVTAAHEATLDVWDQHMAKAGAELLHARLELVELLRPHLARAYAELTDASKPADAIYRSTLQNQMDDDGASLGATGRPGPGDAAAAEDLRGLSIEELTQRYVRAFGESRKKELERGISLVGPHRDDLELVLGQAPAKGYASHGETWSMCLSLRLASYYVMLDDARTGGSAPILILDDVFAELDVQRRRKLAAIVSGAEQVLVTAAVDADIPEELSGRRVKVVPGGIDEQGE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGES2_MACFA
Sequence: MAPATRVVRALWTGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGQGPVAAARKGSPRLLGAAALALGGALGLYHTARWHLHAQDLHAERSAVQLSLSSRLQLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVLRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNDQGKEVTEFGNKYWLMLNEKEAQQVYSGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
What is the function of this protein?
Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro) (PubMed:11866447, PubMed:23426368).  The biological function and the GSH-dependent property of PTGES2 is still under debate (PubMed:23426368).  In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA) (PubMed:23426368).
What are the official names of this protein?
Prostaglandin E synthase 2, Microsomal prostaglandin E synthase 2, mPGES-2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Prostaglandin E synthase 2 truncated form]: Cytoplasm, perinuclear region. Note=Synthesized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region.
Protein: RIBB_AGRFC
Sequence: MTIAKIEDAIEAISRGEMVIVVDDEDRENEGDIIAASDSITPQQIAFMMNHARGLVCVAMPGERLDALDIPLMVSRNTESLKTAFTVSVDYIPGTTTGISAADRAKTVRALVSEGSRPEDFARPGHIFPLRANPEGVLGRTGHTEAAVDLCRLAGKFPSGTICEVANDDGTMARLPQLEIFAERHGLLVVTIKDLVSYLKGEVVEEMVQKQVA
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RL6_BIFLO
Sequence: MASHIGKLPIAIPAGVEVKIEGQNFSAKGAKGSDSYVVPEGITAAVEGNEIVLTAADDLRPTRAKHGLARSIMAGMVKGVHDGYSKTLEIVGTGYRAVAKGQGIEFFLGYSHTITVNPPEGITLKVTDANHVVVEGTDKQVVGQVAANIRKLRAPEPYKGKGIKYSDERILRKAGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CAS5_CANAL
Sequence: MENYLLSSPTQLSQPYDDGTNSLLFMDNYELSQNLSQPLDQHLQSLQQQSQVQSQAPQQVQSLNQHQQLPQIQPFPTLVNNQQYAQETFQQLSQQHQQQQQQQQQFSPFQQSQLQQQFQYQYSQQQQQQHFQQPVTIEEEIVPASNNTNIQISKFFDDNKGDDEDIANSGNFNEFDHSRNISLDDTTITDLHRRENSINPPTGLPHSISSNTIYSYSSFESPQSHIQSQPSYSQGYHNQNSLSTPLRRNKSYSISSANFNQSPVNLATTAMNKIMKTPLRGHTRSRSKVDVNAAVTAAMNLGQATKSNSTSSYNSTLNPFYTPSQQLSSTDDDDISTPLLTPGTKLHTSKSTFFSPYNKDDLEDQDDDAVKQLRKAKSYTSLLRKKKREDMTPSKQNQQHQQQQQQQQQQQQSRQSGGGHIQNLSFPNSTSQPKIDLLAYDQNPMTSYPPMDKSILKNLNQSISPFNKPKLSPPPSNFPSISIDLTTIATNKSSSFSSSTTHRNYNENTPFNSANSTSGGLLPPMATFTVPTVIKEELQVHNLQEEEQEHQDEQMEIDSFESNEKNARPTLSTSSLVRSMKMANLEISNDQQMSSNEDENIVTEAVVKQEKNGPVVDDVNGTGTNSKKPRKKQKSKSKENCNKKGKVATGNGKDNDKNNECLVNKGNKTNNNDTSNDKLDNDNKNTNGNGNNDNDNDSEENNDNVDDADDDDDGTVTIPIPEDLNVTKVKVRNNRSKSNDKSDPKKKHKCPICESRFQRPEHVKRHLKSHSSEKPFECQMPNCGKRFNRKDNLKAHLKKIHGLVKGQEEFTRVLNENKEVS
What is the function of this protein?
Transcription factor involved in the cell wall damage response.  Acts with ADA2 to promote cell wall integrity.  Required for expression of numerous cell wall biosynthesis inhibitor caspofungin-responsive genes.  Plays a key role in adherence, hyphal development, and virulence.
What are the official names of this protein?
Cell wall integrity transcriptional regulator CAS5, Caspofungin sensitivity protein 5.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTU2_PASMU
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKHYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQIGVAYIIVFLNKCDMVDDEELLELVEMEVRELFSQYDFPGDDTPIVRGSALQALNGVAEWEEKILELANHLDTYIPEPQRAIDQPFLLPIEDVFSISGRGTVVTGRVERGIIRTGEEVEIVGIKATTKTTVTGVEMFRKLLDEGRAGENVGALLRGTKREEIERGQVLAKPGSITPHTDFESEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMTVSLIHPIAMDQGLRFAIREGGRTVGAGVVAKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu-B, EF-Tu-B.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM2_STAAS
Sequence: MKFDRHRRLRSSATMRDMVRENHVRKEDLIYPIFVVEKDDVKKEIKSLPGVYQISLNLLESELKEAYDLGIRAIMFFGVPNSKDDIGTGAYIHDGVIQQATRIAKKMYDDLLIVADTCLCEYTDHGHCGVIDDHTHDVDNDKSLPLLVKTAISQVEAGADIIAPSNMMDGFVAEIRRGLDEAGYYNIPIMSYGVKYASSFFGPFRDAADSAPSFGDRKTYQMDPANRLEALRELESDLKEGCDMMIVKPALSYLDIVRDVKNHTNVPVVAYNVSGEYSMTKAAAQNGWIDEERVVMEQMVSMKRAGADMIITYFAKDICRYLDK
What is the function of this protein?
Catalyzes an early step in the biosynthesis of tetrapyrroles.  Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
What are the official names of this protein?
Delta-aminolevulinic acid dehydratase, ALAD, ALADH, Porphobilinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the ALAD family.
Protein: RFCS_HALWD
Sequence: MSEADASDAAPTGREIWIEKYRPATLENIYGQEDTVDRLQSYIDRDDLPHLLFAGPAGVGKCVTGSTPILTNKGIRQIGEIVGDVDGFAPAPQNLKVCSLTADGSFQYRHPSHVFGKRASGLQRIKTNDGATLTVTPEHKLLIRTGENTNPTWVPAADITAGMHVLRAKNLPIPAETTGSCAASKNASEVSHIGDEYRYHDSLMADVNTRIATLERLIEDYAESRSDGSLKFTLIGAHTPTVSTVSYLLATVGIASRHTSTLIDSEKRVHAIIIDASDTVRLEEMIETDWDTVMADQTTTVTSSSTASTTKTTQSYLSSGETQTCGWIPYADGGVTHPSTQHSPLHADVVTVSESLDAEKRVYDLTVPGVRNYVGGCIPTVMHNTTAATAIAHAVYGDDWQNNLLELNASDERGIDVVRDRIKNFARSSFGGYDHRIIFLDEADSLTDDAQSALRRTMEQFADNTRFILSCNYSSKIIDPIQSRCAVFRFSPLSETAIRGQTKDIAAAENIELTEDGLDALVYAAGGDMRRAINSLQAAATTGEVVDEETVYTITSTARPEDIETMVTAAIDGDFTTARSQLQTLLVDTGMAGGDIIDQLHRTAWNLDLDEETTVRLLERVGEADYRITVGANEQVQLEALLASLADTQ
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C small subunit, RFC small subunit, Clamp loader small subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcS subfamily.