PharMolix/UniProtQA huggingface dataset:
Protein: GABR2_HUMAN
Sequence: MASPRSSGQPGPPPPPPPPPARLLLLLLLPLLLPLAPGAWGWARGAPRPPPSSPPLSIMGLMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDAIKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSVKKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYDGIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFRNGERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSVNQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILNLGNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILHHAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
What is the function of this protein?
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:9872316, PubMed:9872744, PubMed:15617512, PubMed:18165688, PubMed:22660477, PubMed:24305054).  Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins (PubMed:18165688).  Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase (PubMed:10075644, PubMed:10773016, PubMed:24305054).  Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis (PubMed:10075644, PubMed:9872744, PubMed:10906333, PubMed:10773016).  Plays a critical role in the fine-tuning of inhibitory synaptic transmission (PubMed:9872744, PubMed:22660477).  Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials (PubMed:9872316, PubMed:10075644, PubMed:9872744, PubMed:22660477).  Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception (Probable).
What are the official names of this protein?
Gamma-aminobutyric acid type B receptor subunit 2, GABA-B receptor 2, GABA-B-R2, GABA-BR2, GABABR2, Gb2, G-protein coupled receptor 51, HG20.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Note=Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane. In contrast, GABBR2 does not depend on GABBR1 for transport to the cell membrane.
Protein: HISZ_BRUMB
Sequence: MVGSRTSPIFNALRVELNAREAELVEIPLIQPADPFLDMAGEDLRRRIFLTENENGDSLCLRPEFTIPVCRNHIALNAATPKRYAYLGEVFRQRRDGAAEFLQAGIEDLGAADEAASDARSLADALSCVKAIAPDAPLEIVLGDQSVFAGMLKALGLPQGWRKKLLRSFGDAHSMDLALAELTGTQRRDPLPESLAVLVAEGDEIGLARMLEAEMLEAGISPGAGRTPVEIARRLIEKEDLAATHFPAAALDLLRQFLAIRVSLDTAAVTLRAFAADNALDLGAVLQKFEARADAIAQAGIEMKDIIYDASFGRPLDYYTGLVYEIRDASNRQDGVLAGGGRYDRLLTMLGACEAIPGVGFSIWLDRLQALAGEKQ
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTRG_METBF
Sequence: MDGKAPAAFVEPGEFNEVMKRLDKIDEKIEFVNSEVAQKIGKKVGRDIGILYGGFIGLLLFLIYTVVSSMFM
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit G, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit G.
What is the protein family that this protein belongs to?
Belongs to the MtrG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CARB_ECOLI
Sequence: MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGADRIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNADFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: MRAY_BACCN
Sequence: MLEQGLLVTAGVAFLISVALSPLFIPFLRKLKFGQSIRDEGPKSHQKKSGTPTMGGIVIYVSMMVTTLIMAIKFEHLGAEVSLLLLVTFGYGLIGFLDDYIKVVKKRNLGLTSKQKLLGQLIIAIAFFAIAKGQGFDTHLMIPGTDITFDLYWAYFILVLFMLIGGSNAVNLTDGLDGLLSGTAAIAFGAFSIIAVAQEQYAVAIFCMAVVGAVLGFLVFNANPAKVFMGDTGSLALGGAIAAVAILLKQELLLVIIGGVFVMETLSVIIQVISFKTTGKRVFKMSPLHHHYELCGWSEWRVVVTFWSVGFLLAVLGIYIGVWM
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL15_BIFLD
Sequence: MADNEILQMHDLKPAPGAKKDRTRVGRGEGSKGKTAGRGAKGQTKRNHVRPGFEGGQLPLYMRLPKLRGFKNPFKVEFQVINIARLVELFPEGGEVAVADLIAKGAVRDNAPVKVLGDGETTVAFTLKGVKASASAKSKIEAAGGSVSED
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: ARGC_STAS1
Sequence: MIEVGIVGGSGYGAIELIRLLIQHPNVNIKYIFSHSKQDQPIKETFPHLEQLTYHYETLNSEGIECDVIFFATPSNVSKHIVPQLLSKRIKIIDLSGDFRLTNRATYETYYGETAASQEYLNEANYSIAEWSNVNAQTTQLIANPGCFPTATLLALHPLIDKDIVKQDNIIIDAKTGVSGAGRSLAQHVHFAEMNENLSAYAIGKHKHKPEIEQYLSLLAQQEVKVTFTPHLVPMTRGILSTIYIKLNHAFTNEDLHNLFKDYYEDKPFVRIRSLGQFPKTKEVYGSNYCDIGIYVDEENQTAILVSVIDNLVKGASGQAIQNLNLMYGWKENTGLLQSPVYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STK25_BOVIN
Sequence: MAHLRGFANQHSRVDPEELFTKLDRIGKGSFGEVYKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDSPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKFITRYTKKTSFLTELIDRYKRWRSEGHGEESSSEDSDIDGDPEDGEQGPIWTFPPTIRPSPHGKLHKGTALHGPQKSAEPVKRQPRSQCLSTLVRPVFGELKEKHKQSGGGVGALEELENAFSLAEESCPGISDKLMAHLVERVQRFSHSRNHLTSTR
What is the function of this protein?
Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress.  Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 25.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus. Note=Localizes to the Golgi apparatus.
Protein: PYRB_STRPC
Sequence: MSVVNNRVALTNLVSMEALTTEEVLGLINRGSEYKAGKVVISDHQKDLVANLFFENSTRTHKSFEVAEKKLGLTVLDFNADASAVNKGESLYDTVLTMSALGTDICVIRHPEDDYYKELVESPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFEGLKIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEEWYSEAFNAYGTYIAIDQIIKELDVLMLLRVQHERHDGHQSFSKEGYHQAFGLTQERYQQLKDSAIIMHPAPVNRDVEIADSLVEAPKARIVSQMANGVFVRMAIIEAILNGRNKNS
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: TLP_BACC3
Sequence: MPNPDNRSDNAEKLQEMVQNTIDNFNEAKETAELSNEKDRSAIEAKNQRRLESIDSLKSEIKDES
What are the official names of this protein?
Small, acid-soluble spore protein Tlp.
What is the protein family that this protein belongs to?
Belongs to the Tlp family.
What are the subcellular locations of this protein?
Spore core.
Protein: SECA_XANOP
Sequence: MINSLLTRVFGSRNERQLRQLTRLVTQINALEPTIEKLSDAELQAKTPEFKQRLAAGESLDKILPEAFAVCREASRRVLGMRHYDVQLIGGMVLHLGKIAEMRTGEGKTLVATLPVYLNALQGEGVHVVTVNDYLARRDAAQMGKLYNWLGLSVGVVYPGMPHSDKREAYGSDITYGTNNEFGFDYLRDNMALSRADRYQRTLHYAIVDEVDSILIDEARTPLIISGPADESPELYIRVNRIVPQLTKQESEEGEGDFWVDEKGKQVHLSEAGMGHAEELLLQAGILENAEDGLYAAQNLSVVHHLNAALRAHAIYQRDVDYIVRDGEVVIVDEFTGRTLSGRRWSDGLHQAVEAKEGVPVQRENQTLASITFQNLFRMYKKLSGMTGTADTEAYEFQSIYGLEVVVIPTNRPTVRKDHPDQVFLNRKGKFNAVLADIEDCAKRGQPVLVGTTSIETSEMLSEHLRKAGVKHEVLNAKQHEREATIVANAGQPGAVTIATNMAGRGTDIVLGGSLESEYHALGEDATEDARFKIKTDWQRRHDAVKAAGGLHIIGTERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDNLMRIFASDWVQKAMRMMGMKEDDVIEDRLVSRQIEKAQRKVEAHNFDIRKNLLDFDDVNNDQRKVIYAQRDELLDAESVKDNVDGIRGDVIYDLVARFVPPNSVDEQWDVKGLEATLESELGVTLSLTDMVRTQEEIDAEQIAAKVQAAVDAHFAEKEAAVGNDTMRALEKHVMLTVLDQGWKEHLAKMDYLRQGIYLRGYAQKQPKQEYKKEAFELFSEMLENVKREVIHLLARVRIRSEEEVAELEEQERLHAQARLMASQFQHQDVGGYGTDEEAAQVQSGNAPLPVSQVTRDEPKVGRNDPCPCGSGKKYKHCHGQLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CYBP_MACFA
Sequence: MASEELQKDLEEVKVLLEKATRKRVRDALTAEKSKIETEIKNKMQQKSQKKAELLDNEKPAAVVAPITTGYTVKISNYGWDQSDKFVKIYITLSGVHQVPTENVQVHFTERSFDLLVKNLNGKSYSMIVNNLLKPISVEGSSKKVKTDTVLILCRKKVENTRWDYLTQVEKECKEKEKPSYDTETDPSEGLMNVLKKIYEDGDDDMKRTINKAWVESREKQAKGDTEF
What is the function of this protein?
May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins.  Probably serves as a molecular bridge in ubiquitin E3 complexes.  Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1) (By similarity).
What are the official names of this protein?
Calcyclin-binding protein, CacyBP.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: MTNA_PECCP
Sequence: MQTLNTTSLKIVDNQLWILDQQALPQEKCWRPCPDVASLVEHIQTLRVRGAPLIGLSASLLLALLAEKGLSQAELAQALETLRASRPTAVNLMNNLDRMKLALAQPQFVAALVQEALRLVEEDRALCERIADHGAALVKPNSRLLTHCNTGGLATAGIGTAIGVLLRAHQQGKVTQVWVDETRPLLQGGRLTAWELGELGIPYQLICDSMAASLMAQGQVDAIWVGADRIAANGDVANKIGTYSLAVLAHYHQIPFYVAAPHTTHDPACPDGRAIPIEQRAAAEVTGVSGSFGHCQWAPQNAAVYNPAFDVTPAALISGWVLDTGVVTPQDVKEGIFQNTLK
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: YBEY_SYNR3
Sequence: MNPLAAIELDLAYLGPDPLGEDRWVELLSSWLAQLQAELPSPLKADAYSLGLQFCDDAAIAELNGQWRQQPKPTDVLSFAAQEDAPEPLEGLPIELGDIVISIPTAERQAPEHGHSLQQELLFLASHGLLHLLGWDHPDEASLAAMLSRQDALVQGAAAH
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_ENT38
Sequence: MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
Protein: TRUA_RIPO1
Sequence: MKGTQTKEKQRVALVIQYLGSRFHGWQWQPNQRTVQAEIENAIAEVLGETVTLHGAGRTDAGVHAAAQVAHFDMVSPIPASRWVDILNARLPEDILIRGSAQVPLTWHARFSAQWRRYRYTFYTEQRPNLFVKPYSWHYYHFPLDESLMQQALNPLLGRHHLAAFHRAGSRRDHSWVEVQSTHCHRQGPFIHLEIQANGFLYGMVRLLVGLLVEVGSGKRSLENFTEIWRKQQREAVKYAAPAKGLCLLRVGYEEFPFPPSLWFDSQPLFLFNQVLDSSLSFPNQSLPYGMTS
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RL31_THEON
Sequence: MPIKPGDEVIFTVPIRKVKKRVPRWKRAPRAARFVREWIARHAKAEEVIIDPAVNEKLWERGTEKPPNKLRVKVKVEEQDGKRVAYVNLAD
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: DXS2_STRAW
Sequence: MPLLTRIRGPRDLDRLSLEQLDQLAEEIRTFLVDAVSKTGGHLGPNLGVVELTIALHRVFDSPKDRVLFDTGHQSYVHKLLTGRQDFSKLKMKGGLSGYPSQAESEHDVIENSHASTVLGWADGLAKANQVLERDDHVVAVIGDGALTGGMAWEALNNIAAAKDRPLVIVVNDNERSYAPTIGGLANHLATLRTTDGYERFLARGKDLLERTPVVGRPLYETLHGAKKGLKDFIAPQGMFEDLGLKYVGPIDGHDIEALESALARAKRFGGPVIVHCLTEKGRGYQPALQDEADRFHAVGKIHPDTGLPIASSGADWTSVFGEEMVKLGQERKDIVAITAAMLQPVGLDKFAKVFPKRVYDVGIAEQHAAVSAAGLATGGLHPVFAVYATFLNRAFDQVLMDVALHKCGVTFVLDRAGVTGTDGASHNGMWDMSILQVVPGLRLAAPRDADQVRAQLREAVDVDDAPTVVRFSKGAVGPAVPAVGRIGGMDVLREPGTDAPDVLLVSVGALAPMCLEIAGLLDKQGISATVVDPRWVKPVDEAMAPLAERHRVVVTVEDNSRVGGVGSAIAQALRDAGVDVPLRDFGIPPRFLDHASRGEVMAEIGLTAPDIARQVTGLVSKLDGRFERPTAEIDSVEPARD
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase 2, 1-deoxyxylulose-5-phosphate synthase 2, DXP synthase 2, DXPS 2.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RL39_CALMQ
Sequence: MATHKPLGFKLRLASAGKSNRNPPAWVMVKTDRKVTYNTKRRNWRRVKLKLG
What are the official names of this protein?
50S ribosomal protein L39e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL39 family.
Protein: GUAAB_METVS
Sequence: MFDAKSFIEESVEDIKKQINGRKTIIALSGGVDSSVAAVLTGKAIGDQLLAVYVDTGLMRKNESNEIWNIFKEQMGLNLKIVEAKDLFLSELAGIDDPEQKRKIIGRIFIEVFEKVAKEQGEEILVQGTIAPDWIESEGQIKTHHNIALPSGMVLEVVEPLRDLYKDEVRKLATELGLPEKIAHRQPFPGPGLAVRILGEITEEKLEICKEANFIVSEEIEKTGLQKELWQYFAAVLDTKATGVKGDIRDYNWVVALRFVKSLDAMTAHTPEIPFDLIKRISKRITSEIPNVTRVVLDVTDKPPATIEFE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: JMJ1_SCHPO
Sequence: MVYRPTAHEFDDLPKIEFIDSCPYQVFLEQYLKPCVPVLIGPKLTAQWKANTTWITSKGDPNILHSYILPDKPCTSRDNTSGNSLLNDNDIKNFIRSYAERIVNNEDKNVFLDSLLLSPNYEYLEENYGTIPVPLAYCNEKDRYGSQRRETVPLKSALHELRDEQVQLQCRQAPSNQALKSLYAKDMHLFRHLDPADFPYSTPDIFADDWLNAYVIDCESDDFRFAYLGSHLTTTGLHTDVYASHSFSVNLCGVKCWLFIDPKDLQTIASLYDDQQLPSWITKDDLFRGPLVNHRHLIKILFQYPGQTVFVPSGWYHQVLNIGTTLSINHNWCNASCILQMYTALKEQYEVSAESLKDLLEDGIVTKDRFSQVVTEVVEANYGWCWRRFWGMIKHQLKRRDAILHSSEYFSKWPIQPEFLPPLSWEYSILKNILLNDEPGSTFDSGSPPSSIVTIFKSLGDFKE
What are the official names of this protein?
JmjC domain-containing protein 1, Jumonji domain-containing protein 1.
Protein: LAEA_HYPAI
Sequence: MSSRNAPSGCVAPSPATAAPPSPTNLRLTVGQSGSESANEPGGEPEERILQDGFWEYGRFYGNWKKGKYNFPIDKEETSRLDILHKYFIVETEDRVTSVPLDKEGSPKIMDLGTGTGIWAFHVVEGYIPNAQIMAVDLNQIQPALIPRGVTTKQFDLEEPSWEPLLRDCDLIHLRLLYGSIRDDLWADTYRKIFEHLAPGGYVEHLEIDWTPQWDGEDHPTHSAIREWSQQFHRAMHRYRRSVKVSSEDTKRMMEAAGFTEFKETKIRCYLNPWSTDRHQREAARWFNLALGLGLEAMSLMPMIDMLHMKQEDVVDLCKRVKAETCVLRYHAYFTLHTWTAKKPASPPQ
What is the function of this protein?
Methyltransferase that performs automethylation (By similarity).  No other methyl-accepting substrate has been identified yet (By similarity).  Component of the velvet transcription factor complex that acts as a global regulator for secondary metabolite gene expression (PubMed:23826217).  Controls the expression of the gamma-pentyl-pyrone gene clusters (PubMed:23826217).  Required for the expression of cellulase (PubMed:23826217).  Regulates asexual sporulation (conidiation) by environmental stimuli such as light and/or mechanical injury (PubMed:23826217).  Required for oxidative stress tolerance (PubMed:23826217).  Also plays a role in defense and parasitism on other fungi (PubMed:23826217).
What are the official names of this protein?
Secondary metabolism regulator LAE1, Methyltransferase LAE1, Velvet complex subunit LAE1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LaeA methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPO3_METST
Sequence: MNIEIREKDDERAVFVVEGVDDTFINTIRRICLVEIPTLAIEDVNIYKNDAKMFDEVLAHRLGLIPIVTDLDSYVMPSECDCESGCQHCRVSFLLKEKCEEGNDSKIVYSKDLKSDDPAVKPVYDTIPIVRLREGEEVELEAIAELGLGSEHAKWQATTTCGYKYYPKIEIDTEKVNDLEEYVEECPRNVLQIEDDTLVVGNIENCSTCRTCQRLSEKDDNAIVVDFEESKYIFKIETDGSLKPFDVLTIACDILSEKADNIINFVNEEE
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHP2_SCHPO
Sequence: MAKDKKDHKHSGSTEDEYDSYLPALMPIAKPLAPKKLNKKMMKTVKKASKQKHILRGVKEVVKAVRKGEKGLVILAGDISPMDVISHIPVLCEDNNVPYLYTVSKELLGEASNTKRPTSCVMIVPGGKKKDMSKVEEYKESYEEIIKEVPALEV
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis (PubMed:10502409).  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1 (By similarity).  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs (By similarity).  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA (By similarity).  Directly binds H/ACA snoRNAs (By similarity).
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit nhp2, H/ACA snoRNP protein NHP2, High mobility group-like nuclear protein 2, P17-nhp2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GLMM_BACMK
Sequence: MGKYFGTDGVRGVANKELTPELAFKIGRFGGYVLTKDTDRPKVIIGRDTRVSGHMLEGALVAGLLSTGAEVMRLGVISTPGVAYLTKALGAQAGVMISASHNPVQDNGIKFFGSDGFKLTDEQEAEIEALLDKEVDELPRPTGTNLGQVSDYFEGGQKYLQYIKQTVEEDFSGLHIALDCAHGATSSLAPYLFADLEADISTMGTSPNGMNINAGVGSTHPEVLAELVKEKGADIGLAFDGDGDRLIAVDEKGNIVDGDQIMFICAKYMKETGQLKHNTVVSTVMSNLGFYKALEANNITSDKTAVGDRYVMEEMKRGGYNLGGEQSGHIILLDYITTGDGMLSALQLVNIMKMTKKPLSELAGEMTKFPQLLVNVRVTDKKLALENEKIKEIIRVVEEEMNGDGRILVRPSGTEPLIRVMAEAPTQEICDGYVHRIVEVVKAEVGAE
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DXR_BRADU
Sequence: MSAVPLRNNKAAASAVRSVTVLGATGSIGDSTMDLLRASPERYRVEALTANGNVEALAKLAKEFSARFVAIADTSKFAELKAALAGTSTECGAGESAVIEAGARPADWVMAAVSGAAGLKPALAAVDRGAHVALANKECLVCAGDFFMQRAAKAGACILPADSEHNALFQALGSGNRDELVRVIITASGGPFRTWKPADIEQATLAQALKHPNWSMGQKITIDSASMMNKGLEVIEASYLFALSPDEIDVLVHPQSIIHGMVEFSDRSVVAQLGSPDMRTPIAHCLGWPDRIKGPAAKLDLAKIGQLTFEAPDFERFPGLRLAYDSLRTGKGATTVYNAANEVAVAAFIAGKIRFGAIARLVEATLEDWIRGGNQTPLTSADDAISVDHVARNRAAALLPQIALKAS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.