PharMolix/UniProtQA huggingface dataset:
Protein: BN3D2_PONAB
Sequence: MAVPTELHGGSVKETAAEKESRVLEPGAAPFGNFPHYSRFHPPEQRLRLLPPELLRQLFPESPENGPILGLDVGCNSGDLSVALYKHFLSLPDGKTCSDASREFRLLCCDIDPVLVKRAEKECPFPDALTFITLDFMNQRTRKVLLSSFLSQFGRSVFDIGFCMSITMWIHLNHGDHGLWEFLARLSSLCRYLLVEPQPWKCYRAAARRLRKLGLHDFDHFHSLTIRGDMPNQIVQILTQDHGMELICCFGNTSWDRSLLLFRAKQTIETHPIPESLIEKGKEKNRLSFQKQ
What is the function of this protein?
O-methyltransferase that specifically monomethylates 5'-monophosphate of cytoplasmic histidyl tRNA (tRNA(His)), acting as a capping enzyme by protecting tRNA(His) from cleavage by DICER1.  Also able, with less efficiently, to methylate the 5' monophosphate of a subset of pre-miRNAs, acting as a negative regulator of miRNA processing.  The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre-miRNAs by DICER1.  Was also reported to mediate dimethylation of pre-miR-145; however dimethylation cannot be reproduced by another group which observes a monomethylation of pre-miR-145.
What are the official names of this protein?
RNA 5'-monophosphate methyltransferase, BCDIN3 domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUH_HUMAN
Sequence: MDHTEGSPAEEPPAHAPSPGKFGERPPPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFFIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS
What is the function of this protein?
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations.  Acts as a transcriptional repressor when it is not associated with Notch proteins.  When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes.  Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively.  Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.  Binds specifically to methylated DNA (PubMed:21991380).  Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) (PubMed:23303788).  Negatively regulates the phagocyte oxidative burst in response to bacterial infection by repressing transcription of NADPH oxidase subunits (By similarity).
What are the official names of this protein?
Recombining binding protein suppressor of hairless, CBF-1, J kappa-recombination signal-binding protein, RBP-J kappa, RBP-J, RBP-JK, Renal carcinoma antigen NY-REN-30.
What is the protein family that this protein belongs to?
Belongs to the Su(H) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Mainly nuclear, upon interaction with RITA/C12orf52, translocates to the cytoplasm, down- regulating the Notch signaling pathway.
Protein: MAO1_SHIBS
Sequence: MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRIIDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: AT222_ASPOR
Sequence: MTVAPPSPNSPAAELQQRPPRYPGEDTTPTSKREIWGWYAYGIAAEVFAVCGVGSFLPLTLEQLAREQGTFKSSHLPCVGPGSPSTSVNGTAPAMLRRDEAENDQCVVGLLGLNINTASFAMYTFSLAVLVQALTLISFSALADYENNRKTLLLAFGFIGSATSMLFVFIAPPIFVLGALLVVIGVTCLGSSFVVLNSFLPVLVANDPSIEKASKPAEELHPMSPDGEYIHPRDSFSASDAESGPHPAAEAGSGTSSGPASPELQLSTRISSKGVGLGYCAAVLVQILSISLLFTLSKTSISKVSGTLPLRFVLLLVGIWWFSFTMVTRKWLRARPGPPLNTANTGGQVKRWRVWLRLVGFAWKSLWKTVKIAVQLREVLVFLAAWFLLSDAMATVSGTAILFARTELKMSTTLVGLLSITATLSGMAGAFLWPVVSRRFGLKSNHTIMLCIALFEIIPLYGMLAYIPVFKKWGVIGLQQPWEIFPLAIVHGVVSGGLSSYCRSFFGLLIPPGSEAAFYALYAATDKGSSVIGPAIVGMLIDATGQVRSGFFFIAPLILMPIPLIWIVNAEKGRREGVAMAQRLEKGHETEMSEQTEEAEGLLARGI
What is the function of this protein?
Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation.  The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation (By similarity).
What are the official names of this protein?
Autophagy-related protein 22-2.
What is the protein family that this protein belongs to?
Belongs to the ATG22 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Vacuole and punctate structures.
Protein: INV4_YEASX
Sequence: MLLQAFIFLLAGFAAKISALMTNETSDRPLVHFTPNKGWMNDPNGLWYDAKEGKWHLYFQYNPNDTVWGLPLFWGHATSNDLTHWQDEPVAIAPKRNDSGAYSGSMVIDHNNTSEFFNDTVDPRQRCVAIWTYNTPESEEQYISYSLDGGYTFTEYQKNPVLAANSTQFRDPKVFWYEPSQKWIMTAAKSQDYKIEIYSSDDLKSWKLESAFANEGFLGYQYECPGLIEVPTEQDPSKSHWVMFISINPGAPAGGSFNQYFVGSFNGTHFEAYDNQSRVVDFGKDYYALQTFFNTDPTYGSALGIAWASNWEYSAFVPTNPWRSSMSLVRKFSLNTEYQANPETELINLKAEPILNISNAGPWLHFASNSTLTKANSFSVDLSNSTGTLEFELVYAVNTTQSVSKSVFSDLSLWFKGLEDPEEYLRMGFEASASSFFLDRGNSKVKFVKENPYFTNRMSVNNQPFKSENDLSYYKVYGLLDQNILELYFNDGDVVSTNTYFMTTGNALGSVNMTTGVDNLFYIDKFQVREVK
What are the official names of this protein?
Invertase 4, Beta-fructofuranosidase 4, Saccharase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: HSV2_SCHPO
Sequence: MSTINTVSLNQDASCMSVALDTGYKIFQINPLKLRAQRQFNDGGLSIVKMLFRSNVLLLVGGGGNPKYAPNKLIVWDDVKERPVKELELNFEIKGICFDGKLLAIATASKLFLYQFGNNLKLQRCLDTQNPKGLCAMVTTVEKTAIVFPSRKVGQLQILFLFKDHMNTSIVPAHDSEISCLGISKTGSKIASSSTNGTLIRIWNSETGEKICEFRRGYQHTAVCQLAFSPDELLLACASKKETLHIFSLHGSPNTIRQLTSEEPYEEASEFKSSTTEPRQTHWKRKLLKLIDSGKRAHWRIQLYQSNPVLLHWLDEMTILICYKDAAYQKLKLTIEESSKSVEHANQHVCFHYDYTLEADGSLC
What is the function of this protein?
Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways.
What are the official names of this protein?
SVP1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: SYT_SHEB9
Sequence: MPVITLPDGSKREFAHAVSTLDVAADIGPGLAKACIAGRVNGELKDACDLIETDAELSIITAKDEEGVEILRHSCAHLLGHAIKQMWPETKMAIGPVIDNGFYYDIDLEHKLTQDDIDALEKRMLQLAKTNYDVVKRVVSWQEARDAFAARGEDYKIAILDENISKDATPALYHHEEYTDMCRGPHVPNMRFCQHFKLMSIAGAYWRGNSENKMLQRIYGTAWADKKALSTHLTRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWSIFLELERFIRRKLNQYTYQEVKGPLMMDRVLWERSGHWDKYSEAMFTTSSENREYAIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGSLHGLMRVRGFTQDDAHIFCTDSQVQEEVSACIQMVYDTYATFGFENIVVKLSTRPEKRIGDDAMWDRAEEALKQALRDNNIEFTILPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDYALPSRLGATYVAEDNSRQTPVMIHRAILGSLERFLGILIEEYAGRFPTWLAPMQVVVMNITDKQADYVEEVVKFFKEQGIRASFDLRNEKIGFKIREHTLRRVPYLLVVGDQEMENKEVAVRTRDGIDLGKMRLEDFATKIHQQISLRSLKLLEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3AT1_ARATH
Sequence: MVAHLQPPKIIETCHISPPKGTVPSTTLPLTFFDAPWLSLPLADSLFFFSYQNSTESFLQDFVPNLKHSLSITLQHFFPYAGKLIIPPRPDPPYLHYNDGQDSLVFTVAESTETDFDQLKSDSPKDISVLHGVLPKLPPPHVSPEGIQMRPIMAMQVTIFPGAGICIGNSATHVVADGVTFSHFMKYWMSLTKSSGKDPATVLLPSLPIHSCRNMIKDPGEVGAGHLERFWSQNSAKHSSHVTPENMVRATFTLSRKQIDNLKSWVTEQSENQSPVSTFVVTLAFIWVSLIKTLVQDSETKANEEDKDEVFHLMINVDCRNRLKYTQPIPQTYFGNCMAPGIVSVKKHDLLGEKCVLAASDAITARIKDMLSSDLLKTAPRWGQGVRKWVMSHYPTSIAGAPKLGLYDMDFGLGKPCKMEIVHIETGGSIAFSESRDGSNGVEIGIALEKKKMDVFDSILQQGIKKFAT
What is the function of this protein?
Involved in the acylation of the 6'' position of the 3-O-glucose residue of anthocyanin.  Also able to use flavonol 3-glucosides as the acyl acceptor.
What are the official names of this protein?
Coumaroyl-CoA:anthocyanidin 3-O-glucoside-6''-O-coumaroyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: UPPP_SHEAM
Sequence: MDTLQVIILALIQGLTEFLPISSSAHLILPAQLFGWEDQGLSFDVAVHIGSLAAVVIYFRNEILAMLKAWLASIFRGQQSDDSKLAWWIILATIPAIGVGFTAKDMVETHLRGPGVIAITTVIFGLLLWFADRIAKDEMTEYQTGWRKALLIGVAQALALIPGTSRSGITITAALMLGLKREAAARFSFLMSIPVILGAALLMTKDIITENHVVDWHALALGSILSFIAAYACIYFFLKIISRMGMTPFVIYRIALGVFLCGFIYL
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDH_MYCLE
Sequence: MRRSIILVSVSVAIAMLTGASIAEAEPMPPNNPSAATRDALWKIVHDRCELGYQHTGAYAPCTLVDEQAGTALFKANYDPNQYLLLPLARVTGIEDPALQELASPNYLYNAWAARGFVSSRLNNSLPEPDIFLAINPKNARTQDQLHIHISCVSPTTAEILKQVNWAEYVGWKPLPVTLQDHTYQALAVNRSTFESKSLFRDIQTKVTADGNTMDHASVAVANIAPDQFLLLVAEGTEDQAIAAEELQDHNCSIAKRLTGQLDMETRR
What are the official names of this protein?
Probable CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GLRX1_PIG
Sequence: MAQAFVNSKIQPGKVVVFIKPTCPFCRKTQELLSQLPFKEGLLEFVDITATSDTNEIQDYLQQLTGARTVPRVFIGKECIGGCTDLESMHKRGELLTRLQQIGALK
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins.
What are the official names of this protein?
Glutaredoxin-1, Thioltransferase-1, TTase-1.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCRB_CORDI
Sequence: MSNKLAEIGNNIDSRYTAASGIRRQINKVFPTHWSFMLGEIALYSFIILLLTGVYLTLFFDPSITKVIYDGAYLPLNGVEMSRAYETALNLSFEVRGGLFIRQMHHWAALTFMVSMTVHMLRIFFTGAFRRPREANWIIGCVLLFLGMAEGFMGYSLPDDLLSGVGLRIMSAIILALPIIGTWLHWLIFGGDFPSDLMLDRFYIAHVLIIPGIILGLIAAHLALVWYQKHTQFPGAGRTENNVVGVRILPVFILETSSFGLVTFGVLALLAGLTSINAIWNLGPYNPSQVSAGSQPDIYMLWTDGAARVMPAWELYIGSYTIPGAFWVALLCGVLVGLLVGYPFIEKKITGDDAHHNLLQRPRDVPVRTSLGVMAIVFYFLLTLSGGNDLFAYHFEVSLNAMTWVGRIGLIVLPPLAYFITYRICLGLQRSDREVLEHGIETGVIKIMPNGAFVEVHQPLGPVDEHGHPVPLPYAGAPVPKQLNDLGFGGEPGRGGYFTPDNDSLAAKYAEIEHENHLEEMAMYKNLQKNNRAQDGVEED
What is the function of this protein?
Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis.  The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain.  The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.
What are the official names of this protein?
Cytochrome bc1 complex cytochrome b subunit, Cytochrome bc1 reductase complex subunit QcrB, Menaquinol--cytochrome c reductase cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SELU_CHRSD
Sequence: MSLPHLAPEMALLERPLIDVRAPVEFARGALPGAVNLPLMDDAERHAVGIRYKEAGQGAAIALGERLVDGDLKARRVAAWRAFAERHPDAVIYCFRGGLRSRIAQQWLQEAGITLPRIQGGWKAMRQCVNAEIEAAAARPVLVVAGLTGCAKTELVQSLDVGIDLEGHARHKGSAFGRHPLQGPSQIDFEHALGAALSHATHGCVVEDESRMIGQLDIPLSFWQTMETAPRIRVEMPLDWRLEQIRKDYIDTLWRTYRDHYGEWLGWSLMRKQLSSALKRVRKRLGSARFQRLQRLQALAFREHQRGNTQAHEAWLAPLMLEYYDPMYRYQLEQSPYEALHVGDWESCLAFARDWSAALPR
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: PROF3_DICDI
Sequence: MTWQAYIDTNLIGSGFISAQILSSADGSSWANSNGFSVSATEAQHILSCFKDSNKASAMGITINNVKNFVLKADDKSIYAKKDAGGVVLVKTNQTILVAVYNSNLQPGAAANACEALGDYLREQGF
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-3, Profilin III.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PDUD_SALTY
Sequence: MEINEKLLRQIIEDVLRDMKGSDKPVSFNAPAASTAPQTAAPAGDGFLTEVGEARQGTQQDEVIIAVGPAFGLAQTVNIVGLPHKSILREVIAGIEEEGIKARVIRCFKSSDVAFVAVEGNRLSGSGISIGIQSKGTTVIHQQGLPPLSNLELFPQAPLLTLETYRQIGKNAARYAKRESPQPVPTLNDQMARPKYQAKSAILHIKETKYVVTGKNPQELRVAL
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Propanediol dehydratase medium subunit, Diol dehydratase medium subunit, DDH medium subunit, Propanediol utilization protein PduD.
What is the protein family that this protein belongs to?
Belongs to the diol/glycerol dehydratase medium subunit family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=Probably located inside the BMC shell.
Protein: HLH3_CAEEL
Sequence: MTASTSSTPSTSTKIPSSSKSSVTKQTKQKRNERERKRVDQVNQGFVLLQERVPKAAGNKAKLSKVETLREAARYIQELQKQLGMSSTSFHNSMPADFPTPEQSPVYPQSVCSMMAQTPSPSYTSPYYPPPQMMSSNQHDMSSHYYQESSSSSASTSGDHHSFYSHTETY
What is the function of this protein?
Probable transcriptional regulator (PubMed:12874127, PubMed:18586090).  May mediate transcriptional activation by binding to the E-box motif 5'-CANNTG-3' (PubMed:9187144, PubMed:12874127).  Plays a role in the differentiation of the hermaphrodite-specific motor neurons (HSN) that are required for normal egg laying (PubMed:18586090).  Might play a role in serotonin production by regulating expression of the tryptophan hydrolase tph-1 which catalyzes serotonin synthesis, in the HSN neurons (PubMed:18586090).  Also plays a role in HSN axon guidance towards the vulva and the ventral nerve cord, possibly by promoting the expression of the netrin receptor unc-40 (PubMed:18586090).  Under feeding conditions, involved in the regulation of the srh-234 chemoreceptor encoding gene expression in the ADL sensory neurons (PubMed:27487365).  Together with hlh-2, involved in the induction of programmed cell death in the sister cells of the serotonergic neurosecretory motor (NSM) neurons, probably through the activation of egl-1 transcription (PubMed:12874127).
What are the official names of this protein?
Helix-loop-helix protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: BPHF_PARXL
Sequence: MKFTRVCDRRDVPEGEALKVESGGTSVAIFNVDGELFATQDRCTHGDWSLSDGGYLEGDVVECSLHMGKFCVRTGKVKSPPPCEALKIFPIRIEDNDVLVDFEAGYLAP
What is the function of this protein?
This protein seems to be a 2Fe-2S ferredoxin.
What are the official names of this protein?
Biphenyl dioxygenase system ferredoxin subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin component family.
Protein: RSMA_PSEPK
Sequence: MNEQYQHRARKRFGQNFLHDAGIIDRILRAINAKAGEHLLEIGPGQGALTEGLLGSGAQLDVVELDKDLVPILQHKFADRSNFRLHQGDALKFDFNQLGVPPRSLKVVGNLPYNISTPLIFHLLSHAGLIRDMHFMLQKEVVERMAAGPGGGDWGRLSIMVQYHCRVEHLFNVGPGAFNPPPKVDSAIVRLVPHEVLPFPAKDHLLLERVVREAFNQRRKTLRNTMKGLLDSAAIEAAGVDGSLRPEQLDLAAFVRLADQLADQQQA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C76A1_SOLME
Sequence: FGNMFDLAGSAPYKKIACLKEKYGPILWLKIGSSMNTMVIQTANSASELFRNHDVSFSDRPIVDVNLAHNYYKGSMALAPYGNYWRFSRRICTVEMFVHKRINETTNIRQESVDKMLRLDEEKASSSGGGGEGIEVTRYMFLASFNMVGNMIFSKDLVTDPESKQGSEFFNAMIGIMEWAGVPNISDIFPCLKMFDVQGLRKKMERDMGKGKEITKKFIEERIEERKKGEKNRSIKDLLDVLIDFEGSGKDEPDKLSEDEITVIILEMFLAGTETTSSSVEWALTELLRHPQAMAKVKLEILQVIGPNKKFEECDIDSLPYMQAVLKEQLRLHPPLPLLIPRKAIQDTKFMGYDIPKGTQVLVNAWAIGRDPEYWDNPFEFKPERFLESKVDVKGQNYELIPFGAGRRMCVGLPLGHRMMHFTFGSLLHEFDWELPHNVSPKSINMEESMGITARKKQPLKVIPKKA
What are the official names of this protein?
Cytochrome P450 76A1, CYPLXXVIA1, Cytochrome P-450EG8.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: VME1_CVHN5
Sequence: MNESIFPHWNSDQAITFLKEWNFSLGVILLLITIILQFGYTSRSMFVYLIKMIILWLMWPLTIILTIFNCFYALNNVFLGLSILFTIISIVIWILYFVNSIRLFIRTGSWWSFNPETNNLMCIDMKGKMYVRPVIEDYHTLTATVIRGHLYIQGVKLGTGYTLADLPVYVTVAKVQVLCTYKRAFLDKLDVNSGFAVFVKSKVGNYRLPSSKSSGMDTALLRA
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: CSPG_SHIFL
Sequence: MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRTLNENQKVEFSIEQGQRGPAAANVVTL
What are the official names of this protein?
Cold shock-like protein CspG, CPS-G.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NS1_I06A0
Sequence: MDPNTVSSFQVDCFLWHVRKRVADQELGDAPFLDRLRRDQKSLRGRGSTLGLDIETATRAGKQIVERILKEESDEALKMTMASVPASRYLTDMTLEEMSRDWSMLIPKQKVAGPLCIRMDQAIMDKNIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLPSLPGHTAEDVKNAVGVLIGGLEWNDNTVRVSETLQRFAWRSSNENGRPPLTPKQKREMAGTIRSEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: OPLA_MOUSE
Sequence: MGSPEERFHFAIDRGGTFTDVFAQCPGGHVRVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRGEPGAGSPVKGCTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDMGGTSTDVSRYAGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCPASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSYTPETFAQLDQRLSRLEEQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCSPRAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTGRSGLQLEETSKIQSGPPHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRISVGAEAPSMIDTKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQSRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQAPGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACAASQGCMNNVTLGNARMGYYETVAGGAGAGPGWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRPGSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRKDGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPEDPAPPPGSPPLYPAFPERGSVYEYRRAQEAV
What is the function of this protein?
Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase, 5-oxo-L-prolinase, 5-OPase, Pyroglutamase.
What is the protein family that this protein belongs to?
Belongs to the oxoprolinase family.