PharMolix/UniProtQA huggingface dataset:
Protein: FUS_MEASC
Sequence: MGLKVNVSAIFMAVLLTLQTPTGQIHWGNLSKIGVVGIGSASYKVMTRSSHQSLVIKLMPNITLLNNCTRVEIAEYRRLLRTVLEPIRDALNAMTQNIRPVQSVASSRRHKRFAGVVLAGAALGVATAAQITAGIALHQSMLNSQAIDNLRASLETTNQAIEAIRQAGQEMILAVQGVQDYINNELIPSMNQLSCDLIGQKLGLKLLRYYTEILSLFGPSLRDPISAEISIQALSYALGGDINKVLEKLGYSGGDLLGILESRGIKARITHVDTESYFIVLSIAYPTLSEIKGVIVHRLEGVSYNIGSQEWYTTVPKYVATQGYLISNFDESSCTFMPEGTVCSQNALYPMSPLLQECLRGSTKSCARTLVSGSFGNRFILSQGNLIANCASILCKCYTTGTIINQDPDKILTYIAADHCPVVEVNGVTIQVGSRRYPDAVYLHRIDLGPPISLERLDVGTNLGNAIAKLEDAKELLESSDQILRSMKGLSSTSIVYILIAVCLGGLIGIPALICCCRGRCNKKGEQVGMSRPGLKPDLTGTSKSYVRSL
What is the function of this protein?
Class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes.  Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.  This fusion is pH independent and occurs directly at the outer cell membrane.  The trimer of F1-F2 (F protein) probably interacts with H at the virion surface.  Upon HN binding to its cellular receptor, the hydrophobic fusion peptide is unmasked and interacts with the cellular membrane, inducing the fusion between cell and virion membranes.  Later in infection, F proteins expressed at the plasma membrane of infected cells could mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis (By similarity).
What are the official names of this protein?
Fusion glycoprotein F0.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses fusion glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass membrane protein.
Protein: PCID2_CAEEL
Sequence: MPSVRSIEDYFGQIESLLYRQDWTNGEKISKFVSTYDEHAQEPFMHIEAYGSRSKRCRVSEDEVFDEIVCLHLHVLYNIHVAQDLITAQSTQIQIIQLFNKEILQKRKDENWFLPIFYRLCTDLRWLSKGAEACVSGDDEGDSNANSFFESAAKAITECYRTCVSDVHAEEGTTKKVAMLNMTNQLFQIYFQINKLNLLKPLIRAIDNCGSLYHDFLMSDKVAYNYFLGRKAMFDADLNLAEKSLLYAFRNCPADSMSNKRKILIYLIPVKMFLGHMPTSQLLHEYRLDEFQDVVAGVKDGNLAQLDGALAANEAFFIKCGIFLMLEKLRMITFRTLFKKVSQIVGTAQIPLDAFQTALRFVGVTDVDMDELECIIANLIASKKIKGYLSHQHQKLVISKMNAFPTLSGVSSN
What are the official names of this protein?
PCI domain-containing protein 2 homolog, CSN12-like protein.
What is the protein family that this protein belongs to?
Belongs to the CSN12 family.
Protein: CLPS_STRM5
Sequence: MPRESSPDSHHEHGVAVEPARPEVAPPPFYQVMLLNDDYTPMDFVVDVLQQFFTMDLDKATQVMLHVHTRGRGVCGVFTREVAETKVAQVNEYSRMNQHPLLCTMEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: CDCA7_HUMAN
Sequence: MDARRVPQKDLRVKKNLKKFRYVKLISMETSSSSDDSCDSFASDNFANTRLQSVREGCRTRSQCRHSGPLRVAMKFPARSTRGATNKKAESRQPSENSVTDSNSDSEDESGMNFLEKRALNIKQNKAMLAKLMSELESFPGSFRGRHPLPGSDSQSRRPRRRTFPGVASRRNPERRARPLTRSRSRILGSLDALPMEEEEEEDKYMLVRKRKTVDGYMNEDDLPRSRRSRSSVTLPHIIRPVEEITEEELENVCSNSREKIYNRSLGSTCHQCRQKTIDTKTNCRNPDCWGVRGQFCGPCLRNRYGEEVRDALLDPNWHCPPCRGICNCSFCRQRDGRCATGVLVYLAKYHGFGNVHAYLKSLKQEFEMQA
What is the function of this protein?
Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells.  Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis.  May play a role as transcriptional regulator.
What are the official names of this protein?
Cell division cycle-associated protein 7, Protein JPO1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163.
Protein: PAMR1_BOVIN
Sequence: MELGWWPQLGLAFLQLLLISSLPREYTVINEACPGAEWNIMCRECCEYDQIKCECPGKKEVVGYTIPCCRNEENECDSCLIHPGCTIFENCKTCRNGSWGGTLDDFYVKGIYCAECRAGWYGGDCMRCGQVLRVPKGQILLESYPLNAHCEWTIHAKPGFIIQLRIVMLSLEFDYMCQYDYVEVRDGDSSDSQIIKRFCGNERPAPIRSTGSSLHILFHSDGSKNFDGFHAIFEEITACSSSPCFHDGTCLLDSTGSYKCACLAGYTGKHCENLLEERNCSDPGGPVNGYKKITGGPGLIHGHYAKIGTVLTFFCNSSYVLSGNEMRTCQQNGEWSGKQPICIKACREPKISDLVRRKVLPMQVQSRETPLHQLYSSAFSKQKLQDAPTKKPVLPFGDLPPGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKTENVSAPKTQGTRWPWQAAIYRRAGGVHGGGLHKDAWFLVCSGALVNERTVVVAAHCVTDLGRVTVIKTADLKVVLGKFYRDDDRDEKSIQSLRISAIILHPNYDPILLDMDIAILKLLDKARMSTRVQPICLAAPRDLSTSFQESRITVAGWNVLADSRSPGYKDDMLRSGVVRVADSLLCEEQHEAQGIPVSVTDSMFCAGRDPTAPSDICTAETGGIAAVSFPGRASPEPRWHLVGLVSWSYDKTCSHSLSTAFTKVLPFKDWIERNMK
What is the function of this protein?
May play a role in regeneration of skeletal muscle.
What are the official names of this protein?
Inactive serine protease PAMR1, Peptidase domain-containing protein associated with muscle regeneration 1, Regeneration-associated muscle protease homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SSRP_COXBN
Sequence: MNKQISKKPAQRTIALNKKALHDYYVEQRFEAGLVLEGWEVKSIRAGRVQLRDSYVVFKGGEAWLIGAHLSPLPNVAEYMKADPQRSRKLLLNKREIGKLFGAVQKQGLTVVPLDLHWHKNHVKVEIALAKGKKTHDKRETIKRREWEREKHRVLKSHG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ANMK_COXBR
Sequence: MPKERYIGLISGTSMDALDTALVQFDPLKIIATHGEPIPTELKKNLVALSTGTDNSIPSMGETDVALGRLFGEAVLTLLEKAKVSSDSIQAIGSHGQTIRHMPNGKHPFTLQIGDPNTIAALTGITTVADFRRRDMALGGQGAPLAPAFHEFLLRDQSENRLILNIGGIANLTFLPRDPEKSTIGFDTGPGNTLLDAWCLMNLNKDYDDQGQWAASGRVQEKLVAQLLAEPYFQTPPPKSTGREYFNLNWLKKNLNGEKFDPVDIQATLVELTARSVANCCRNFSMDSGSLWLCGGGARNHHLVNRLKVLCKPLRVTTTEEIGIHPDWLEAVCFAWLAKQTLEKKPGNLPSVTGAKKSAILGAIYWGEKFNY
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: LAC4_ARATH
Sequence: MGSHMVWFLFLVSFFSVFPAPSESMVRHYKFNVVMKNVTRLCSSKPTVTVNGRYPGPTIYAREDDTLLIKVVNHVKYNVSIHWHGVRQVRTGWADGPAYITQCPIQPGQVYTYNYTLTGQRGTLWWHAHILWLRATVYGALVILPKRGVPYPFPKPDNEKVIVLGEWWKSDTENIINEALKSGLAPNVSDSHMINGHPGPVRNCPSQGYKLSVENGKTYLLRLVNAALNEELFFKVAGHIFTVVEVDAVYVKPFKTDTVLIAPGQTTNVLLTASKSAGKYLVTASPFMDAPIAVDNVTATATVHYSGTLSSSPTILTLPPPQNATSIANNFTNSLRSLNSKKYPALVPTTIDHHLFFTVGLGLNACPTCKAGNGSRVVASINNVTFIMPKTALLPAHYFNTSGVFTTDFPKNPPHVFNYSGGSVTNMATETGTRLYKLPYNATVQLVLQDTGVIAPENHPVHLHGFNFFEVGRGLGNFNSTKDPKNFNLVDPVERNTIGVPSGGWVVIRFRADNPGVWFMHCHLEVHTTWGLKMAFLVENGKGPNQSILPPPKDLPKC
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products (By similarity).  Required for secondary xylem cell wall lignification.
What are the official names of this protein?
Laccase-4, Benzenediol:oxygen oxidoreductase 4, Diphenol oxidase 4, Protein IRREGULAR XYLEM 12, Urishiol oxidase 4.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: NUPG_SHIFL
Sequence: MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAQVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHMQLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMAMFKYKHVRVPTGTQTVSH
What is the function of this protein?
Broad-specificity transporter of purine and pyrimidine nucleosides.  Transport is driven by a proton motive force.
What are the official names of this protein?
Nucleoside permease NupG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Nucleoside:H(+) symporter (NHS) (TC 2.A.1.10) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y496_LEUMM
Sequence: MFRNSDFDIFEDKTLNGRMEKIRTIIDPKFEEFASIALPILNTNGQEWYAHVAKHLRRTTYAPDNTWVAFAPNKRGYKMLPHFELGIWEDNVYFYLAVEENMKPDQTNVITQKLREVSPLVRELPDSYRLSQDHMVNKTYSLLQYDDSIERYESVKHSEVLIGVEIKRGDKLWDGDGIVDTLVLAMKNLLPIYEKIK
What are the official names of this protein?
UPF0637 protein LEUM_0496.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: DNAJ_HALMT
Sequence: MSEDFYDVLGVSRDASKDQIKNAYRKKAAKYHPDVSDEEDAEEKFKKVQKAKEVLTDDEKRQMYDQLGHERFQQAQKRGAGGGGGGRGQGNPFGGGGNPFGGMGGGGFEDIFNNLFNGGGGQRRSRPQQGRDVAQRITIDLEDAYHGVERDVTIRRREVCPECDGEGHPADADVNTCSECNGSGQQTTVQQTPFGRVQQTTTCRACGGEGKTYSEDCSECRGSGRVRRTRDVTITIPAGFRDGQRLRYRGEGEPGENGGPNGDLFVEVNVRDHEEFDRDGDDLQYTHPISFPQAVFGATVEVPTLDGEAELKVPAGTQSGSTFTVSGAGMPHLDGRGNGDLHVEIHVVTPEDLNSEQREALKQFAEAGGEEVKESLFQKLKNSL
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_SINMW
Sequence: MDAIVKNFPVLDDTSGRPTQKEAEEAVRVLLRWAGEDPAREGLKDTPARVAKAYREIFGGYDLAAEDVLGRTFEEVSGYDDIVLEKDIPFYSHCEHHMVPIIGKAHIAYLPNGRVLGLSKIARVVDIYARRLQTQEAMTAQIARAIDETLVPRGVAVMIEAEHLCMAMRGIKKQGATTMTTTFTGEFKSEPAEQVRFMTMLRGFK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: RL28_LACLA
Sequence: MSKECYFTGRKTVSSNNRSHAMNQTKRVVKPNLQKVTILENGELKTVWASAKALKKLPAGVERV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: FIXB_ECO55
Sequence: MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGVQAIQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTISVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
What is the function of this protein?
Required for anaerobic carnitine reduction.  May bring reductant to CaiA.
What are the official names of this protein?
Protein FixB.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
Protein: YQGF_ESCF3
Sequence: MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRTN_STAAS
Sequence: MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIEQGV
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product.
What are the official names of this protein?
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming), Dehydrosqualene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family. CrtN subfamily.
Protein: RSMA_STRZT
Sequence: MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEIDDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDILKVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRISAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVEDENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLAEFAGLADALKGQGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_PAUCH
Sequence: MVSIAGQIGWEAVIGIETHVQLGTASKIFTQASTNFGDDPNTNINPVVCGLPGTLPVLNQKVLEYAVKAAMALNLKVSEHSKFDRKQYFYPDLPKNYQISQYDEPIAEDGWIEVEIAEKEKQTYTKRIGIERLHMEEDAGKLVHIGSDRLTGSNHSLIDYNRAGIALAEIVSKPDLRTGREAAEYASEIRRIMRYLGVSDGNMQEGSLRCDVNISVRKGKNAPFGIKIEIKNMNSFSAIQKACEYEISRQIKAINNGERIIQETRLWDENKQLTTSMRSKEVASDYRYFPDPDLGPIEIELDRREAWKHELPELPAIKRHRYVEELGLSIYDARIITDELPMAEYFESAITAGAEAKALANWLMGDISAYLNTNKTTIGEIKLRPSQLAELIILISNGEISGKIAKEILPELIEKGLSPSALIDDKGLAMISDNNQIRTIIVELLSLYPEEVKAFRNGKIKLQGFFVGQLMKKTSGKADPKISNKILLEILNASEN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln).  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, organellar chromatophore, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Plastid, organellar chromatophore.
Protein: SECA_SHEFN
Sequence: MLGKLLTKVFGSRNDRTLKNLGKIVIQINALEADYEKLSDEELKAKTTEFRTRLENGETLDNIMAEAFAVVREASKRVFDMRPFDVQLLGGMVLDSNRIAEMRTGEGKTLTATLPAYLNGITGKGVHVITVNDYLATRDAENNRPLFEFLGLSVGINVAGLGQFEKKQAYDADITYGTNNEFGFDYLRDNMAFSPQERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYAKINLLIPSLIPQDKEDTEDYVGEGDYSIDEKGKQVHLTERGQEKVELLLIEKGMLAEGDSLYSATNISLLHHVNAALRAHTLFEKDIDYIVQDDEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGAKIQNENQTLASITFQNYFRQYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVRKDMADLVYLTAPEKYAAIIKDIEGCRERGQPVLVGTVSIEQSELLNSLLKKANIPHSVLNAKFHEKEAEIVAQAGSLGAVTIATNMAGRGTDIVLGGNWNMEIEALENPTAEQKAKIKADWKIRHDEVLAAGGLHILGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDSLMRIFASDRVSGMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEYDDVANDQRQVVYAQRNELMDAESIQDTIQNIEQDVISGIVDQYIPPQSLEELWDVPGLEQRLGNEFGLKLTIQEWLDQDDNLHEETLRERILTSWSELYKAKEEMVGAQVLRQFEKAVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQLLETLKNDVISVLSKVQVQAQSDVDEMEQRRRDEEAKIKLAYQHASVEALSDAGEQQIEAPKTVIREGEKIGRNDPCPCGSGQKYKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MIAB_SERP5
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLGSTHGYQWTDNAEEADVLLLNTCSIREKAQEKVFAMLGRWRLLKEKNPALIIGVGGCVASQEGEHIRSRAPCVDVVFGPQTLHRLPEMLNHVQGTRSPIVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTFCVVPYTRGEEVSRPSDDVLFEVAQLAAQGVREVNLLGQNVNAYRGATYDGGICSFAELLRLVAAIDGIDRIRYTTSHPIEFTDDIIAVYEDTPELVSFLHLPVQSGSDRILTMMKRAHTALEYKAIIRKLRKARPDIQLSSDFIIGFPGETQADFEQTMNLIAEINFDTSFSFIYSSRPGTPAADMVDDVSEDEKKQRLYILQDRINQQVLQFSRRMLGTVQRILVEGTSRKSVMELAGRTACNRMVNFEGTPDMIGQFVDVEITEVLTNSLRGTVVRTEQQMDLRVHESPQSVIARTRKENALGVGIYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VHUD_METKA
Sequence: MSEESVVVAFCCYEUGYGAADLAGTGRAQYPSSVRIVRVPCTGRVGIEHILTALAKGAWTVFVAGUKKGECSYEDGNLKCERRVQAAKKLLEELGIEPERVEIYFMSSAEADKFVAAVKEMHERAKELGPLA
What are the official names of this protein?
F420-non-reducing hydrogenase vhu iron-sulfur subunit D.
What is the protein family that this protein belongs to?
Belongs to the MvhD/VhuD family.
Protein: GATB_BORPA
Sequence: MNWEIVIGLETHTQLSTDSKIFSGSSTRFGAAPNTQANAVDLALPGSLPVMNRGAAERAILFGLAVGGKVAPRSVFARKNYFYPDLPKGYQISQYELPVVEGGTLSFFVGEEEKTVNLTRAHLEEDAGKSLHDEFSLASGAPASGIDLNRAGTPLLEIVTEPEMRSAAEAVAYARALHSLVVWLGICDGNMQEGSFRCDANVSVRPVGQKEFGTRTEIKNVNSFRFLERAILFEARRQIELIEDGGTVVQETRLYDADRDETRSMRSKEDAHDYRYFPDPDLPPLVIGQDWVDAVRAGMPELPTAQRARFEADYGLPAYDAAQLTVSRAMADYFEAVARALPAGQAKLAANWIMGEVAATLNREEKDIDAAPVSAAALATLINRIIDGTISNKIARDVFAAMWAGENGGDADAIIAARGLKQISDSGAIGAMIDEVLAANPAIVEEYRAGKQKAFNSLVGQIMKAAKGKANPQQVNELLKEKLG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: ARSCL_ECOLI
Sequence: MSNITIYHNPACGTSRNTLEMLHNNGNEPTIINYLDMPPTRDELIKLISDIFSDKIIECIREQCHLMPALSLNVIGHVDIRSIHSYLFNFNEKVSPSHGFIKNG
What is the function of this protein?
Reduction of arsenate [As(V)] to arsenite [As(III)].  This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance (By similarity).
What are the official names of this protein?
Putative arsenate reductase, Arsenical pump modifier.
What is the protein family that this protein belongs to?
Belongs to the ArsC family.
Protein: DAS1_YEAST
Sequence: MPFQDYFQKKKAAFINRNNKSNADASALRDINDININFAAKSKNYVFPLTKLPDELMQEVFSHLPQPDRLQLCLVNKRLNKIATKLLYRRIYLNDSNVVKSDFMHLAINWTLLNLPSSLKEEESRDIANCKLKKLIETLQNNIHITEVIQWIRINWDLDSTLQRSILSILCNQGKSLQRLENVTDPACNDIISNGHFSRSNVSSFDMAPPNSLPEMVVPENYIPNLTKYLSQRISSRLSHMTLFIDPLKLFNYLYPLDIKLQIIDLKLHWRREFYNNDYFVKKIRPGNPLTKLSEVFDKRTLKILTIISWNDTLLKRETEMLKDFKEFENLEDLSLISIKQDVHILVDLFSSLTNLKRLKMDFLEEYVPEPTNPHIFLSILLACSKLQFIDLRYDGLIPQIINIQENKFQLNQQCNCTNCQIVFSDILKGKIFMFPEDYYIHDLQDIAAKDIFKMMKYLSLLPYSKACDAYPSVRTQPMNLTNFVTKMNRNLLEYRNSKSQLVPKIVNNPHQHSTVTSTSTAHMSEPEMIIIDDDDDDDEINAAIPPSSDDTAATISTDLELPHESLTKRDIIMCYHALIHHFKSIYVTFLKSFPHLRFLMLNDIPTIVMEENNERIFEPVFYHYDYKSNLYGWSKESNKNLENDSNNNNNNSDTIARIATVM
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Probably recognizes and binds to phosphorylated target proteins (By similarity).
What are the official names of this protein?
F-box protein DAS1, DST1-delta 6-azauracil sensitivity protein 1.
Protein: Y4336_RHIME
Sequence: MKTPWKFLARLASRQPSGKTQESSAGNDTGSKTLEHTSALPPSPTVAASPLARNEDVSVDQGPIASDKPAGHNGVAQALEPPIHADEAQTTARDEADQSGAEANSLAPKSTASTKSQRKPRIKRRERGKRANARVDAQSAVVQKHYQNLQQSSSRDLFFHELATLDEEIKMLRTQLAQKLHLQNVQLKKMLERFELS
What are the official names of this protein?
Uncharacterized protein RA0936.
What is the protein family that this protein belongs to?
To Rhizobium NGR234A y4nF and y4aO.
Protein: YL027_MIMIV
Sequence: MKSENTAFKKTAEGIYEFLDNPLQLTSEKFKSEIEPLLKNPEVKYVLIDSREDYNHQGDKIIRNNLRLVKSWYKNTLEDASLTEKEIYKLVWLPKEKVMDDLMNQGSFWPEEWLFSMKSYYNIPHISLLKKSLDTVKSDKNQNKFQ
What are the official names of this protein?
Uncharacterized protein L27.