PharMolix/UniProtQA huggingface dataset:
Protein: GYRB_HAEIN
Sequence: MSETTNDNYGASSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCSDIIVTIHDDNSVSVQDDGGGIPVDIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSDKLQLTIRRQGHVHEQFYHLGEPQSPLTVIGETEATGTTVRFWPSSDIFAITTFDYKILAKRLRELSFLNSGVSIRLIDKRDGSEDHFHYEGGIQAFVEYLNKNKNPIHPKPFYFTAEKDGIGVEVALQWNDGVNENVYCFTNNIPQRDGGTHLAGFRGALTRSLNSYMENEGMLKKEKVATSGDDAREGLVAIISVKVPDPKFSSQTKDKLVSSEVKSAVESAMNEKMQEYLLENPADAKIIVNQIIMAARAREAARKAREMTRRKGALDIAGLPGKLADCQEKDPALSELYLVEGDSAGGSAKVGRDRKTQAILPLKGKILNVEKARFDKMLSSQEVGTLITALGCGIGRDEYNPDKLRYHHIIIMTDADVDGSHIRTLLLTFFYRQMPELIERGYVYIAQPPLYKVKKGKQERYIKDADEMEQYELTLALDGAELHISTNAPAMNALVFEKLVAEYNSVQKLIGRLNRHYPAPVLQGLIYQSPISIEMMKEESAVENWGKSFVEQLTAKETEAHQYSVRTQFNAERQVYEAVITVRKHGIDTDYFLNFDFVHGNEYAKIVSLNKQLNGLLEEGAYVIRGEKVQPVRSFEQAVEWLVKESRKGLEVQRYKGLGEMNADQLWETTMDPNSRRMLKVSIKDAVAADQLFTTLMGDEVEPRREFIELNALRANLDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRR_BACAN
Sequence: MQEKAVVLDDQMIRRALTRISHEIVERNKGVDNCVLVGIKTRGIFIAQRLAERIGQIEGKEMEVGELDITLYRDDLTLQSKNKEPLVKGSDIPVDITKKKVILVDDVLYTGRTVRAAMDALMDLGRPSQIQLAVLVDRGHRELPIRADYVGKNIPTSSEERIEVDLQETDQQDRVSIYDK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: PDXA_DESOH
Sequence: MNPRPLIGITMGDPVGIGPEIILTALAGTSVYEKCRPLVIGDPGVLGQAMAVAGYAPVIHMTDTPETGVYRPGTISMFSPAPPLSPVTWGEPTPETGGAMEAWITTAVDMAMAGAISAMVTCPINKEALKMAGSAFAGHTEMLAMRTGTNRYAMMLAGNRLRVVLVTIHTALQNVPGLLSVDAIADTILLTVESLKQRFGMNAPRVAVAGLNPHAGEGGLFGDEEARLITPAIEAARRKTEAAITGPWPPDTVFVKAAAGDFDAVVCMYHDQGLIPFKLLHFEDGVNTTLGLPIIRTSVDHGTAYDIAGTGRADCRSLTAAIDMAIDQAACLGKRPAA
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHBP_ECOK1
Sequence: METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFYILTEEKTRHAQMSGPQAAIAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRNSGTEQA
What are the official names of this protein?
UPF0306 protein YhbP.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: SYV_STRCO
Sequence: MTENSQQPQPAPSTELPTQYTPAEVEGQLYERWVERGYFEADAKSDKPPYTVVIPPPNVTGSLHLGHAFEHTLIDALTRRKRMQGYETLWQPGMDHAGIATQNVVERELGKEGKSRHDLGREAFVERVWQWKSESGGQISGQMRRLGDAVAWSRERFTMDEGLSQAVQTIFKRLYDDELIYRAERIINWCPRCLTAISDIEVEYQDDDGELVSMKYGEGDETIVVATTRAETMLGDTAVAVHPEDERYKHLVGKLIKLPLTDRSIPVVADEHVDPEFGTGAVKVTPAHDPNDFEIGQRHGLPAIAVMDEHAVITAHGPFQGQDRLEARSAIVAALRAEGRIVAEKRPYVHSVGHCSRCKTTIEPRLSMQWWVKVGPLAKAAGDAVRDGKVKIHPQEMEKRYFDWVDNLHDWCISRQLWWGHRIPVWYGPEGEVVCVGPGEEPPSGEGWYQDSDVLDTWFSSGLWPFSTLGWPEQTESLAKFYPNSVLVTGYDILFFWVARMMMFGLYAMDGTPPFHTIALHGMVRDQNGKKMSKSFGNVVNPLDWMDKYGSDALRFTLARGANPGVDVPIGEDWVQGSRNFANKIWNATRFALMNGATVEGPLPDASRMSSTDRWILSRLNSVVAEVDAYYEDYQFAKLSDALFHFAWDEVFDWYVELSKTTFQAGGEAAEVSKRVLGEVLDVTLRLLHPVVPFVTETLWTTLTGGESVVIAEWPTDSGFRDAGAEREIETVQSVITEVRRFRADQGLQPGQRVPARLTLAGSALAAHEAAVRQLLRLQPEGDAFTATATLPVAGVEVALDLSGVIDFAAERKRLAKDLAAAEKEKAQANAKLGNEAFLAKAPDQVVDKIRGRLAKADEDITRITAQLEKLPEA
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS2_KLULA
Sequence: MLPVVPVFNAVNALKEKTYLYLSSQLVLDGKDMTKDDILEFVQNSHGQNISVLLKDAKFEDDDLIVLLNNGVVTLFIDSDDYAAHLVEIGVPSIRLTLLKDGAYQFSFGQIQEIQQSQLVKASEISLETFTNSVLSGMKTDRPDGLYTTLVVDENERSLGLVYSNKESVSLAIETQTGIYFSRSRNEIWRKGATSGNVQKLLSIELDCDGDALKFVVRQGGSGSFCHLETESCFGNFRHGLYGLQKLLQERLLNAPEGSYTKRLFNDSDLLTAKIKEEAEELTEAVDKKDIAWECADLFYFAMARLVANGVSLEDVERNLNTKHLKITRRKGDAKPKFLKKEPVAVHEEDGKIVLNVVSASDKAAVEKAVTRPIQKTAEIMNLVNPIIENVIKNGDKALVELTAKFDGVQLETPVLEAPYPEEYLDGLTDELRDALDLSIENVKKFHAAQMQSETLDVETQPGVVCSRFPRPIEKVGLYIPGGTAILPSTALMLGVPAQVAGCKEIVFASPPRKSDGRVSPEVVYVASKVGASKIVLAGGAQAIAAMAYGTESVPKVDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVICDEEADVDFVASDLLSQAEHGIDSQVILVGVSLSDSKIEALQNAVHEQAMQLPRVDIVRKCIAHSSIILCDSYEEAFKMSNQYAPEHLILQISNAEDYVKDVDHAGSIFVGAYTPESCGDYSSGTNHTLPTYGYARQYSGVNTATFQKFITSQVVTPVGLEHIGHAVMSVAKVEGLDAHRNAVKIRMSKLGLLPSGFE
What are the official names of this protein?
Histidine biosynthesis trifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the histidinol dehydrogenase family.
Protein: UTP25_LEPMJ
Sequence: MAPFRGRGGFRGGARGASMSRGRRGAARGGAKRGGFAAARTADQVEESNTQFRQAPESEHSQPESSDESASEAEDDEDSEDAQPASAIYATLLQSMSARKTPFGGTVVDPPHVSHRKKRKLHHHVPGPEEVPGAALMPEEGHAHPRGDDQGSETNGPASGGEDHEEEGEAEDLDEEEEQQRLDNTEDSPFDAHFANPDENELAVRLKRITDNQWITKKLDVGRGRGVLQVPAADEIALSRRKVRSTRDVVLKARLVDNAQKVLGNFDDTEQAIAPSIFDYQDLLFGARTVQNAGRLRDIICLHALNHILMTRDRVIKNNAKLAAATDDVDAEYRDQGFTRPKILFLLETKQACVRLLDSITKLHDFEQQENKKRFLESFSLPEDKFSDEKPADFRELFEGNDENEFRIGVKLTRKTLKLYSTFYNSDIILASALGLRRAIESGDPKKRDSDFLSSIEMVIMEQADATLMQNWEHAEFVFEHLNLQPKDPHDCDFSRVRSWYLDDQARHIRQTIVLSAYLTPKINTLYNKYMRNVAGRLKYTQDYTTGLIETLSYGIKQTFLRFDSPSHLTDPDARFKYFNTSILPSISRLPKTPEGGPGVLVFIPSYLDFVRVRNSLVDSDFSYASISEYTDTTDVRKARSHFMNGKHSLLLYTGRAHHFHRYNIRGVKRVVFYGVPENPRFYDEILGFVGKTVERGEVSRAEAGVRVCFSRWERLELERIVGSKRIVRMIADKGDVFDFV
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AROC_KLEP7
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYGAIKDLFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAAKFGIVIRGCLTQMGDIPLAIKDWDQVEQNPFFCPDPDKIDALDELMRGLKKEGDSIGAKVTVVADGVPPGLGEPVFDRLDADIAHALMSINAVKGVEIGDGFEVVKLRGSENRDEITKAGFQSNHAGGILGGISSGQQIVANIALKPTSSITVPGHTINRFGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHFMRQRAQNGDVTTTIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RS10_LACDB
Sequence: MANEKIRIRLKSYEHSILDESGAKIVDTAKRTGAEISGPVPLPTERTLFTVLRSPHKNKDSREQFEMRTHKRLIDILNPTPKTVDSLMKLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GLMS_BACSH
Sequence: MCGIVGYIGQLDAKEILLKGLEKLEYRGYDSAGIAVANEQGIHVFKEKGRIADLREVVDANIEAKAGIGHTRWATHGEPSYLNAHPHQSALGRFTLVHNGVIENYVQLKQEYLQDVELKSDTDTEVVVQVIEQFVNGGLDTEEAFRKTLTLLKGSYAIALFDNENRETIFVAKNKSPLLVGLGDTFNVVASDAMAMLQVTNEYVELMDKEMVIVTDDQVVIKNLDGDVISRASYIAELDASDIEKGTYPHYMLKETDEQPVVMRKIIQTYQDENGKLSVPGDIAAAVAEADRIYIIGCGTSYHAGLVGKQYIEMWANVPVEVHVASEFSYNMPLLSKKPLFIFLSQSGETADSRAVLVQVKALGHKALTITNVPGSTLSREADYTLLLHAGPEIAVASTKAYTAQIAVLAVLASVAADKNGIDIGFDLVKELGIAANAMEALCDQKDEMEMIAREYLTVSRNAFFIGRGLDYFVCVEGALKLKEISYIQAEGFAGGELKHGTIALIEQGTPVFALATQEHVNLSIRGNVKEVAARGANTCIISLKGLDDADDRFVLPEVNPALAPLVSVVPLQLIAYYAALHRGCDVDKPRNLAKSVTVE
What is the function of this protein?
Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
What are the official names of this protein?
Glutamine--fructose-6-phosphate aminotransferase [isomerizing], D-fructose-6-phosphate amidotransferase, GFAT, Glucosamine-6-phosphate synthase, Hexosephosphate aminotransferase, L-glutamine--D-fructose-6-phosphate amidotransferase.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDB25_FUSPC
Sequence: MVKSLRFGDLDVPVPGFGAMGISFALGNDLSYEQAEPVLLEALKQGCTFWDTAVSYGPGKNEKLIGEFVKKHNCRDKLFIASKCGVAAFEDGSITNSAEHIQAYIEGTIERLGFTPDLYYIHRMDPNTPLEESIPAMDLLRKQGKTKYIGLSECSAETLRKANSIAKIDAVQAEYSAFETLHETDGLVDTARELDISFIAYAPLGHGWLVENFPYETPDDFAPDDYRRQIPKWQGDNFYANKRIADKFKELARKKNCTLPQIAIAWIAAQGMIAIPGTTKPERLIENFAAREIEIAEEENKEMRKLVDALKPQGDRYSESAMKNIGK
What is the function of this protein?
Aldo-keto reductase; part of the Fusarium detoxification of benzoxazolinone cluster involved in the degradation of benzoxazolinones produced by the host plant (PubMed:26296598, PubMed:25727347, PubMed:26828593).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (By similarity).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the gamma-lactamase FDB1 to aminophenols (PubMed:26296598).  FDB1 is able to convert 2-benzoxazolinone (BOA) into 2-aminophenol (2-AP), as well as 6-methoxy-2-benzoxazolinone (MBOA) into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26296598, PubMed:25727347).  The N-malonyltransferase FDB2 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:26296598).  FDB2 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:26296598).  The cluster contains also 2 transcription factors (FDB3 and FPSE_08121), an aldo-keto reductase (FPSE_08125) that possibly associates with a ketone component of BOA and MBOA degradation, an esterase (FPSE_08126), an acyl-CoA transferase (FPSE_08120), a solute carrier protein (FPSE_08119) and a transmembrane transporter (FPSE_08127) proposed to shuttle metabolites of benzoxazolinone degradation (Probable).
What are the official names of this protein?
Aldo-keto reductase FPSE_08125, Fusarium detoxification of benzoxazolinone cluster protein FPSE_08125, FDB cluster protein FPSE_08125.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: SECM_SODGM
Sequence: MGILNRWRQIGRRYFWPHLLLGIVAAGFGVPLLPGGGQEMLYQADNCPSLSRQSAFQAGFSQLARLKDVPCRTTYAVDYWHQHAIRTVIRHLSIAWAPAPLPEAVAPLRVQHQVLLTTLGLLLNREARPPVLVRRLRSTGHVAFIDNRSGIRLTQQQGIRAGPHAAV
What is the function of this protein?
Regulates secA expression by translational coupling of the secM secA operon.  Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation (By similarity).
What are the official names of this protein?
Secretion monitor.
What is the protein family that this protein belongs to?
Belongs to the SecM family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Periplasm. Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease.
Protein: IHFB_NITEC
Sequence: MTKSELISKLAERFPQLLAKDAELVVKIILDAMAKSLARGERIEIRGFGSFDLNYRPSRVGRNPKSGEKVHVPEKYVPHFKAGKKMRELIDSSHKQHNLLDQATG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ATPD_SYNJA
Sequence: MISSTMAARVVDPYAEALVSLASAQGLLDTFEADIRFIAAVVQATPELGQFLASPLVKAEAKKNLLQQVFADQIHPLLLNALKLLSDRRRIMFLGAVCQRFLELQRKLKNIVLAEVTTAVPLTEAQQQSIRERVRDFTQASGVELQTSQDPTLLGGVIIKIGSQVIDLSLRGQLRRLALQLA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: PTPH_MIMIV
Sequence: MNFHPELSKISQVTNNIFLSGVFPMEQDPTVIKKLNIKYILACLDRQYVSDAHNAVLIDNPECTILYLPYDDDVSQNLWCKNKNTINLVKYTRTMEEYNCLYKQFQMYQNKPMIEIGYHFINNAVESGNNILIHCMAGISRSVSTLTYYLMKKYNIPYSQAIKYVKDRRSIVNPNDSFKLQLQGYQSKKENFIESDGKKVTDFFKYGQSRLK
What are the official names of this protein?
Putative tyrosine-protein phosphatase R622.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Protein: APT_WOLSU
Sequence: MSVLDENQKQFLLDSIRNIPDFPKPGIQFKDITTLLNDPKAFGFLIDFLTDRYARFELDYVAGIESRGFIFGAALAAKLEVGFVPIRKKGKLPSTTIAEKYSLEYGFDEVEIHIDAFREKEGSRVLLIDDLIATGGTAEAAVKLIQSAKGHCVEACFLLNLEELGGAKKVSNLAPLYTLLDI
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCA_RICRS
Sequence: MQIIEIREPEQADFKPEQQIAVGIDFGTTNSLIAIAANRKVKVIKSIDDKELIPTTIDFTSNNFTIGNNKGLRSIKRLFGKTLKEILNTPALFSLVKDYLDVNSSELKLNFANKQLRVPEIAAEIFIYLKNQAEEQLKTNLTKAVITVPAHFNDAARGEVMLAAKIAGFEVLRLIAEPTAAAYAYGLNKNQKGCYLVYDLGGGTFDVSILNIQEGIFQVIATNGDNMLGGNDIDVVITQYLCNKFDLPNSIDTLQLAKKAKETLTYKDSFNNDNVSINKQTLEQLILPLVERTINIAQECLEQAGNPNIDGVILVGGATRTPLIKDELYKAFKIDILSDIDPDKAVVWGAALQAENLIAPHTNSLLIDVAPLSLGMELYGGIVEKIIMHNTPIPISVVKEFTTYVDNQTGIQFHILQGEREMAADCRSLARFELKGLPPMKAGYIRAEVTFSIDADGILSVSAYEKISNTSHAIEVKPNHGIDKTEIDIMLENAYKNAKIDYTTRLLQEAVIEAEAFIFSIERAIAEFTTLLSESEISIINSLLDNIKEAVHARDWILINNSIKEFKSKIKKSMDTKFNVIINDLLKGKNINQIK
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: NTPPA_METFK
Sequence: MDINMTRIYLASRSPRRAELLHQIGVAFVIIPSDIDESVYNAELAEDYVLRLARGKAQSCCARLPALDMPVLAADTTVCVDGKILGKPESDTEACAMLASMSGRWHEVHTAIAVASRDGTEVALSTTRVKMAALSRDVIAAYVSTGEPRDKAGAYGIQGLGGTLIERIEGSYSGVMGLPLFETAKLLRNCGVAIPGTQD
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARL11_MOUSE
Sequence: MGSVNSRGHKAEAQVVMMGLDSAGKTTILYKLKGNQLVDTLPTVGFNVEPLEAPGHVSLTLWDIGGQTQLRATWKDYLEGIDLLVYVLDSTDEARLPEAVAELKEVLEDPNMAGVPFLVLANKQEAPGALPLLEIRNRLGLEGFQKHCWELRACSALTGQGLQEALQSLLHLLKSR
What is the function of this protein?
May play a role in apoptosis.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 11.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
Protein: MAEA_PONAB
Sequence: MAVQESAAQLSMTLKVQEYPTLKVPYETLNKRFRAAQKNIDRETSHVTMVVAELEKTLSGCPAVDSVVSLLDGVVEKLSVLKRKAVESIQAEDESAKLCKRRIEHLKEHSSDQPAAASVWKRKRMDRMMVEHLLRCGYYNTAVKLARQSGIEDLVNIEMFLTAKEVEESLERRETATCLAWCHDNKSRLRKMKSCLEFSLRIQEFIELIRQNKRLDAVRHARKHFSQAEGSQLDEVRQAMGMLAFPPDTHISPYKDLLDPARWRMLIQQFRYDNYRLHQLGNNSVFTLTLQAGLSAIKTPQCYKEDGSSKSPDCPVCSRSLNKLAQPLPMAHCANSRLVCKISGDVMNENNPPMMLPNGYVYGYNSLLSIRQDDKVVCPRTKEVFHFSQAEKVYIM
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1.  MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex.  MAEA is required for normal cell proliferation.  The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity).  Plays a role in erythroblast enucleation during erythrocyte maturation and in the development of mature macrophages (By similarity).  Mediates the attachment of erythroid cell to mature macrophages; this MAEA-mediated contact inhibits erythroid cell apoptosis (By similarity).  Participates in erythroblastic island formation, which is the functional unit of definitive erythropoiesis.  Associates with F-actin to regulate actin distribution in erythroblasts and macrophages (By similarity).  May contribute to nuclear architecture and cells division events (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein transferase MAEA, Macrophage erythroblast attacher.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Note=Detected in a nuclear, speckled- like pattern (By similarity). Localized with condensed chromatin at prophase; Detected in nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis (By similarity). Present in cytoplasm, nuclear matrix and at the cell surface in macrophages; predominantly nuclear in immature macrophages and predominantly detected at the cell surface in mature macrophages. Colocalizes with F-actin in macrophages (By similarity).
Protein: TRPC_XYLFA
Sequence: MSNILTKIIAWKVEEIAERLLHVSQAELVARCADLPTPRGFAGALQATIAHGDPAVIAEIKKASPSKGVLREDFRPAEIAISYELGGASCLSVLTDVHFFKGHDDYLSQARDACTLPVLRKDFTIDPYQVYEARVLGADCILLIVAALDDAQLVDLSGLALQLGMDVLVEVHDIDELERAIQISAPLIGINNRNLSTFNVSLETTLTMKGLVPRDRLLVSESGILTSADVQRLRAAGVNAFLVGEAFMRATEPGESLREMFFIT
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MURB_WOLPM
Sequence: MLISLPKVRGIYRYDVLMSKATWLNVGGRADVLFKPCDIEDLTYLIKNTELPVSVIGATSNIIVRDSGIRGITVKLGKEFAYIKSKGNNSIVAGGAVLLSNLAHFAGNQQISGLEFLVGIPGTVGGGIEMNAGAYGSDIASVVQSIKAVNLEDGNLYEFSSEEMGYFYRGHSLKGNWIFVEAEFKGVNSEYELILQRLKEVIERKNKSQPIRGKTAGCIFKNPKNYRAWELIDKSGCLRLNIGGARISKKHCNFLLNYDNATASDLENLGNKVKDAVKDKFNVELEWEIRVLGSY
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBB_PROHO
Sequence: MGLPWYRVHTAVINDPGRLLAVHLMHTALVLGWAGSMALYELAVFDPSDAVLNPMWRQGMFVLPFMTRLGVTHSWSGWTVTGEPWINEPGFLNAHFNFWSYEGVALMHIVLSGLFFLAAVWHWVYWDLDLFEDPRTGEPALDLPKIFGGHLFLLGFLCFNFGTFHLTGIFGPGMWVSDAYGLTGHIEHIAPEWGPAGFNPFNPGGVVAHHIAAGITLMIGGVFHLTARPPERLYTALRMGNVETALASAIAAVFGAAFVVAGTMWYGHVTTPIELFGPTRYQWDQGYFTQEIQRRVDSQLAEGASLSEAWSSIPEKLAFYDYVGNSPAKGGLFRVGAMDSGDGIAEEWLGHPVFQDGAGRALSVRRLPNFFENFPVILTDGDGVVRADIPFRRSESQYSFEQTGVTVSFYGGALDGQTFTNPSDVKKFARRAQLGEAFDFDTETLGSDGVFRTSTRGWFTFGHACFALLFFFGHIWHGARTLFRDVFAGIDADLGEQIEFGAFQKLGDLTTRKS
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP47 reaction center protein, PSII 47 kDa protein, Protein CP-47.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbB subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MVP_CGMVW
Sequence: MSLSKVSVENSLKPEKFVKISWVDKLLPNYFSILKYLSITDFSVVKAQSYESLVPVKLLRGVDLTKHLYVTLLGVVVSGVWNVPESCRGGATVALVDTRMHSVAEGTICKFSAPATVREFSVRFIPNYSVVAADALRDPWSLFVRLSNVGIKDGFHPLTLEVACLVATTNSIIKKGLRASVVESVVSSDQSIVLDSLSEKVEPFFDKVPISAAVMARDPSYRSRSQSVSGRGKRHSKPPNRRLDSASEESSSVSFDDGLQSDHT
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Forms a ribonucleoprotein complex with viral RNA.  Binds microtubules and modulates microtubule stability.  Can bind double-stranded DNA.
What are the official names of this protein?
Movement protein, 28.8 kDa protein, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the tobamovirus movement protein family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton. Host cell junction, host plasmodesma.