PharMolix/UniProtQA huggingface dataset:
Protein: LEUD_ALKEH
Sequence: MEPFIKHKGLVAPLDRANVDTDAIIPKQFLKSIRRTGFGPFLFDEWRYLDEGQPDMDCSQRPVNPDFVLNQARYQGASILLTRRNFGCGSSREHAPWALKDFGFRAIIAPSFADIFYNNCFKNGLLPLVLTEAQVDRLFKEVEAAPGYELEIDLPEQQVRTPAGEAFEFEIDGFRKHALLEGLDEIGLTLQHAEDIRAYEARRREQAPWLFTDLEEGR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: GPA8_DICDI
Sequence: MGCYQSRVQVEDKTNEQLDKYLVQAGKEGLLDFRILLLGAGESGKSTVVKQLKSIYKIQVDDDELHSYAVNIHKNTVLCMQVLLEAGETLGIELTDPETKKRAINVKSFQFEPEVKQMPVSIGLDIEELWRDEDIQKIWDRRSEYWFLDATPYYFENIQRFLDDDFVPTEEDCIMTRVRTTGISVTEFDEGPVHFRVVDVGGQRNERKKWIHCFDDVKALLFVVNLAGYDQVMFEDPSQNRMQESLTLFGQICNNPIFSETPTFLVLNKKDLFEQMIQKTDLSKCFPDYKGGSDVKTALEFIQMKYQQKIQESNKPLHTFHIAARYKKDIKYTWEEAKGILLEENKKVLMKATKDLKKSSKQSSKSSLGNSTQNNSNNNNNNNNSNNNNGQTTIDGATAKINS
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.  G alpha-8 is a potential analog for the G(s)-like G-proteins which stimulate adenylate cyclase in mammals.
What are the official names of this protein?
Guanine nucleotide-binding protein alpha-8 subunit, G alpha-8.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family.
Protein: GBRG2_HUMAN
Sequence: MSSPNIWSTGSSVYSTPVFSQKMTVWILLLLSLYPGFTSQKSDDDYEDYASNKTWVLTPKVPEGDVTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCFEDCRTGAWRHGRIHIRIAKMDSYARIFFPTAFCLFNLVYWVSYLYL
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2538761, PubMed:29950725).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:23909897, PubMed:25489750, PubMed:27864268).  The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity).  The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (PubMed:23909897, PubMed:25489750).  The alpha2/beta2/gamma2 receptor exhibits synatogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity).  Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cytoplasmic vesicle membrane.
Protein: U548_DICDI
Sequence: MFCFRKPSDSDIKQYINDRREEQFAYSNLYGTQDYATKEEYEMDPKYSNFDVDQVKIQLGTGVECFQKAVAALKQWKHFDLDWVDFYFKNTPIAVGETVGILSKQVGFWILSFARINYLYDGDQEDGSIKFGYSYGTLKDHVEKGEERFVIEWVRDPDGAPDKGAVYYEMLSFSEPSYWLSQLGYPVTRYFQNKFVVDSCNQMLKAVGSNQNVRHV
What are the official names of this protein?
UPF0548 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0548 family.
Protein: TNIP2_HUMAN
Sequence: MSRDPGSGGWEEAPRAAAALCTLYHEAGQRLRRLQDQLAARDALIARLRARLAALEGDAAPSLVDALLEQVARFREQLRRQEGGAAEAQMRQEIERLTERLEEKEREMQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAECCQ
What is the function of this protein?
Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG.  Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation.  Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific.  Required for stability of MAP3K8.  Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival.  May act as transcriptional coactivator when translocated to the nucleus.  Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes.
What are the official names of this protein?
TNFAIP3-interacting protein 2, A20-binding inhibitor of NF-kappa-B activation 2, ABIN-2, Fetal liver LKB1-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIR1_HHV8P
Sequence: MSVRTFCQVHLGAVPPERRGSQVSAGQLSDFDMCAQSLIDFLKVRVGWDVRANAMAGRLWHQIMEARCPATLKQYLGIFRGVLGHRVESFIQKNIDALEDMLCAYRRSKAYEDTLNCGYLSAVRLYDTYVLRTMGTEPVYESVAQMFMRVSVFVACQCLEHECLYWLARDLIEDAKSVSEMAIVEYVFGYLAAQHVCCATPILRSAGVEGGQLASCFILQPSMMNEPGTLDALYHDMSPLLASKSGVGLDVTSFSHQKNIASCLKLVDAQVHYFNDNNIRPVGASAYMELWHSQICDFLNAKLPENPDRCHSLFQGVCIPTLFFRMYEKDPSKLWYLFDPATAPNLIKLYGAAFDNEYERLVRAGKYVSCMPLKSMMFTLIHTIIKTGSPYVLLKEALNEHHWTDTQGMAINCSNLCAEIVQLPGRNTSVCNLANICLPKCLRTVESARVGTTDANRPFFCFEALGDAVRVAVLVINACILGGSHPTPGVERGQKERSMGIGVQGLADVFAELGYGYLDAESAELDKNIFQSMYYTAVETSHNLVLEGQGVPFHGWEVSNFAKGRFHWQTWEGEDASFVPRHRWDALGKSIAEHGIFNSQFLAVMPTAGTSQVTGYAESVYPFFANISSKVTNKEEVLRPNVTFFKKVLPDDLRVVRQYGGDVSTFPKHHRERYRVFLTAFDYCPFKLLDRARARAPFVDQSQSMSFFLKEDRVRNASYLRDLLLHGYRLGLKTLMYYCRVQKQSSLTALQCLADPGSPPHSGMKQDGAWLPGPKNPEEESCAADPECLVCQ
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells, as well as reactivation from latency in infected hosts.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase large subunit, R1, Ribonucleotide reductase large subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase large chain family.
Protein: STCU_EMENI
Sequence: MSSSDNYRLDGKVALVTGAGRGIGAAIAVALGQRGAKVVVNYANSREAAEKVVDEIKSNGSDAISIQADVGDPDAVTKLMDQAVEHFGYLDIVSSNAGIVSFGHVKDVTPDEFDRVFRVNTRGQFFVAREAYRHLREGGRIILTSSNTASVKGVPRHAVYSGSKGAIDTFVRCLAIDCGDKKITVNAVAPGAIKTDMFLSVSREYIPNGETFTDEQVDECAAWLSPLNRVGLPVDVARVVSFLASDAAEWISGKIIGVDGGAFR
What is the function of this protein?
Versicolorin reductase; part of the gene cluster that mediates the biosynthesis of sterigmatocystin (ST), a polyketide-derived furanocoumarin which is part of the most toxic and carcinogenic compounds among the known mycotoxins (PubMed:8017929, PubMed:8643646).  The first step in the biosynthesis of sterigmatocystin is the production of hexanoate by the fatty acid synthase (FAS) units stcJ and stcK (PubMed:8962148).  The polyketide backbone is assembled by the non-reducing polyketide synthase stcA by condensation of the starter hexanoyl-CoA and 7 malonyl-CoA extender units followed by cyclization and release of norsolorinic acid (By similarity).  Norsolorinic acid is the first stable intermediate in the biosynthesis of sterigmatocystin and is converted into averantin (AVN) by the ketoreductase stcE which reduces the hexanoate ketone to an alcohol (PubMed:8643646) (Probable).  Averantin is then oxidized into 5'-hydroxyaverantin (HAVN) by the cytochrome P450 monooxygenase stcF (PubMed:10618248).  5'-hydroxyaverantin is further converted to 5'-oxyaverantin (OAVN) by the 5'-hydroxyaverantin dehydrogenase stcG (PubMed:24957370).  The next step is the conversion of OAVN into averufin (AVF) which is catalyzed by a yet to be identified enzyme (PubMed:24957370).  The cytochrome P450 monoxygenase stcB and the flavin-binding monooxygenase stcW are both required for the conversion of averufin to 1-hydroxyversicolorone (PubMed:10618248).  The esterase stcI probably catalyzes the formation of versiconal hemiacetal acetate from 1-hydroxyversicolorone (PubMed:24957370).  The oxydoreductase stcN then probably catalyzes the biosynthetic step from versiconal to versicolorin B (VERB) (PubMed:24957370).  The next step is performed by the versicolorin B desaturase stcL to produce versicolorin A (VERA) (PubMed:8999832).  The ketoreductase stcU and the cytochrome P450 monooxygenase stcS are involved in the conversion of versicolorin A to demethylsterigmatocystin (PubMed:7486998).  The Baeyer-Villiger oxidas stcQ and the reductase stcR might be involved in the biosynthetic step from versicolorin A to demethylsterigmatocystin (PubMed:24957370).  The final step in the biosynthesis of sterigmatocystin is the methylation of demethylsterigmatocystin catalyzed by the methyltransferase stcP (PubMed:8900026).
What are the official names of this protein?
Versicolorin reductase stcU, Sterigmatocystin biosynthesis cluster protein U.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RL4_STRZJ
Sequence: MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGNEFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: SYM_CUPMC
Sequence: MTARRILVTSALPYANGQIHIGHLVEYIQTDIWVRFQRMMGNEVYYVGADDTHGTPVMLRAEKEGITPKQLIDRVWTEHKRDFDNFLVSFDNYYSTDAEENRQLCEKIYLALKAEDLITERDVEQFYDPVKNMFLPDRFIKGECPKCGAKDQYGDSCEVCGTTYVPTDLKNPYSVVSGATPVRKSSTHFFFKLSDPRCETFLREWVADLAQPEASNKMQEWLGAEGEASTLSDWDISRDAPYFGFEIPGAPGKYFYVWLDAPIGYYASFKNLAEKRGIDFDAWVGPHSTAEQYHFIGKDILYFHTLFWPAMLRFSGYRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYTDTGMNPEWLRYYFAAKLNASMEDLDLNLDDFVARVNSDLIGKYVNIASRAAGFLVKRFDGKVNEAALANPLLEQLRQAAPQLAQYYEGREYSKALRLVMELTDAVNAFVDTNKPWELAKDESKRDALHAACSVSLEAFRLLTIYLKPVVPTMAAGVERFLNVDPLDWRAIDKQLSADRPVQPYQHLMTRVDVKQIDALLAANRDSLQAAAPAAEAGAAGASAIEPVADTITIDDFAKIDLRVAKIVACDKVEGSNKLLQLTLDLGEGKTRNVFSGIQSAYTPEQLVGKLTVVVANLAPRKMKFGMSEGMVLAASAADEKANPGLYILEPHSGAVPGMRIR
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCMA_METLD
Sequence: MSTKLRYLHHPASQPCRAVHQFMLENNIEFQEEIVDITTDINEQPEFRERYNPTGQVPILVDGDFTIWESAAIVYYLSEKYDCSSSWWGSTLEERGHIQQYMHWYAYTLRLGGGAFHWTIFAPMIYGYDKDFTVEVTKGRFLLYESFDILEKYWLKDGDYLCGNTLSYPDLATCQDLVSHDAGRIIPTSMWDSHPKVKAWFARMMDREHAKTVSAWQYENVRKYLDDGVKLNFQRKTAVLKGTEVYSGHNNGIIYNGDDDSFVTQHG
What are the official names of this protein?
Dichloromethane dehalogenase, DCM dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_PSEE4
Sequence: MTQMWWRDACQPLDTAAMDQARARQQQLTKPTGSLGQLEGLAIRLAGLQGRERPTVEQVAITIFAGDHGVVEEGISAYPQAVTGQMLRNFVSGGAAISVLARQLEASLEVVDLGTVDPSLDLPGVRHLRLGAGTGNFARQAAMTDAQLAAALQAGRDSALRALERGAQLFIGGEMGIGNTTAAAALACTLMGCPARELSGPGTGLDSAGVRHKAEVIERALVLHGLRADEPLRALGHVGGFEIAALVGAYLACAQHGLAVLVDGFICSVAALVAVRLNPQCQPWLLFAHQGAEPGHKALLAALHAEPLLALGLRLGEGSGAALAVPLIRLACALHGQMATFAEAAVADRPA
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: UBP36_HUMAN
Sequence: MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQKIEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDPPARRQGSEHTYESCGDGVPAPQKVLFPTERLSLRWERVFRVGAGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKLDRQTQATTLVHQIFGGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANIVRALELFVKADVLSGENAYMCAKCKKKVPASKRFTIHRTSNVLTLSLKRFANFSGGKITKDVGYPEFLNIRPYMSQNNGDPVMYGLYAVLVHSGYSCHAGHYYCYVKASNGQWYQMNDSLVHSSNVKVVLNQQAYVLFYLRIPGSKKSPEGLISRTGSSSLPGRPSVIPDHSKKNIGNGIISSPLTGKRQDSGTMKKPHTTEEIGVPISRNGSTLGLKSQNGCIPPKLPSGSPSPKLSQTPTHMPTILDDPGKKVKKPAPPQHFSPRTAQGLPGTSNSNSSRSGSQRQGSWDSRDVVLSTSPKLLATATANGHGLKGNDESAGLDRRGSSSSSPEHSASSDSTKAPQTPRSGAAHLCDSQETNCSTAGHSKTPPSGADSKTVKLKSPVLSNTTTEPASTMSPPPAKKLALSAKKASTLWRATGNDLRPPPPSPSSDLTHPMKTSHPVVASTWPVHRARAVSPAPQSSSRLQPPFSPHPTLLSSTPKPPGTSEPRSCSSISTALPQVNEDLVSLPHQLPEASEPPQSPSEKRKKTFVGEPQRLGSETRLPQHIREATAAPHGKRKRKKKKRPEDTAASALQEGQTQRQPGSPMYRREGQAQLPAVRRQEDGTQPQVNGQQVGCVTDGHHASSRKRRRKGAEGLGEEGGLHQDPLRHSCSPMGDGDPEAMEESPRKKKKKKRKQETQRAVEEDGHLKCPRSAKPQDAVVPESSSCAPSANGWCPGDRMGLSQAPPVSWNGERESDVVQELLKYSSDKAYGRKVLTWDGKMSAVSQDAIEDSRQARTETVVDDWDEEFDRGKEKKIKKFKREKRRNFNAFQKLQTRRNFWSVTHPAKAASLSYRR
What is the function of this protein?
Deubiquitinase essential for the regulation of nucleolar structure and function (PubMed:29273634, PubMed:19208757, PubMed:22902402).  Required for cell and organism viability (PubMed:29273634, PubMed:19208757, PubMed:22902402).  Plays an important role in ribosomal RNA processing and protein synthesis, which is mediated, at least in part, through deubiquitination of DHX33, NPM1 and FBL, regulating their protein stability (PubMed:29273634, PubMed:19208757, PubMed:22902402).  Functions as a transcriptional repressor by deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, such as CDKN1A, thereby preventing histone H3 'Lys-4' trimethylation (H3K4) (PubMed:29274341).  Specifically deubiquitinates MYC in the nucleolus, leading to prevent MYC degradation by the proteasome: acts by specifically interacting with isoform 3 of FBXW7 (FBW7gamma) in the nucleolus and counteracting ubiquitination of MYC by the SCF(FBW7) complex (PubMed:25775507).  In contrast, it does not interact with isoform 1 of FBXW7 (FBW7alpha) in the nucleoplasm (PubMed:25775507).  Interacts to and regulates the actions of E3 ubiquitin-protein ligase NEDD4L over substrates such as NTRK1, KCNQ2 and KCNQ3, affecting their expression an functions (PubMed:27445338).  Deubiquitinates SOD2, regulates SOD2 protein stability (PubMed:21268071).  Deubiquitinase activity is required to control selective autophagy activation by ubiquitinated proteins (PubMed:22622177).  Promotes CEP63 stabilization through 'Lys-48'-linked deubiquitination leading to increased stability (PubMed:35989368).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 36, Deubiquitinating enzyme 36, Ubiquitin thioesterase 36, Ubiquitin-specific-processing protease 36.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm.
Protein: BPC2_ARATH
Sequence: MDDDGFRNWGYYEPAAATFKGNLGLQLMSTIDRNTKPFLPGRDPNLMMGPNGSYHHQEPPIHMSYNWINQQKDKFFNMLPVTTATPNYGNVLPETSSAPSMQMNLHHHLQTEENPVKLEEEIVVQTKKRKTNAKAGSTPKAKKPRKPKDENSNNNNNNNTNVTRVKPAKKSVDLVINGVSMDISGLPVPICTCTGAPQQCYRWGCGGWQSACCTTNISMHPLPMSTKRRGARISGRKMSQGAFKKVLEKLASDGFNFGNPIDLKSHWARHGTNKFVTIR
What is the function of this protein?
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
What are the official names of this protein?
Protein BASIC PENTACYSTEINE2, AtBPC2, GAGA-binding transcriptional activator BBR/BPC2.
What is the protein family that this protein belongs to?
Belongs to the BBR/BPC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COL14_ARATH
Sequence: MGTSTTESVVACEFCGERTAVLFCRADTAKLCLPCDQHVHSANLLSRKHVRSQICDNCSKEPVSVRCFTDNLVLCQECDWDVHGSCSSSATHERSAVEGFSGCPSVLELAAVWGIDLKGKKKEDDEDELTKNFGMGLDSWGSGSNIVQELIVPYDVSCKKQSFSFGRSKQVVFEQLELLKRGFVEGEGEIMVPEGINGGGSISQPSPTTSFTSLLMSQSLCGNGMQWNATNHSTGQNTQIWDFNLGQSRNPDEPSPVETKGSTFTFNNVTHLKNDTRTTNMNAFKESYQQEDSVHSTSTKGQETSKSNNIPAAIHSHKSSNDSCGLHCTEHIAITSNRATRLVAVTNADLEQMAQNRDNAMQRYKEKKKTRRYDKTIRYETRKARAETRLRVKGRFVKATDP
What are the official names of this protein?
Zinc finger protein CONSTANS-LIKE 14.
What is the protein family that this protein belongs to?
Belongs to the CONSTANS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL4_STRA1
Sequence: MANVKLFDQTGKEVSSVELNEAIFGIEPNESVVFDVVISQRASLRQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLPQKVRRLALKSVYSAKVAEDKFVAVENLSFAAPKTAEFASVLSALSIDSKVLVILEEGNEFAALSARNLPNVTVATATTASVLDIVNADKLLVTKEAISTIEGVLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: PA2X2_BOTPA
Sequence: SLFEFAKMILEETKRLPFPYYGAYGCYCGWGGQGQPKDAT
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that shows presynaptic neurotoxicity.  10 ug/ml of this protein produce complete neuromuscular blockade up to 70 minutes, without inhibiting the responses to acetylcholine (ACh), but with a partial inhibition (67%) of the response to potassium chloride (KCl).
What are the official names of this protein?
Phospholipase A2 neuwieditoxin-2, NeuTX-2, PLA2, Neuwieditoxin-II, NeuTX-II, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_EHRCR
Sequence: MLYNFIHNIHKEGYIFIMISFLASCIGFAISCSLGIICLVISLLCIYFFRDPIRMVPEGDDLITSPADGLILDIKEVNSPIDDSTQVVCISIFLNVLNVHVNRIPVSGTIKATEYIPGRFISASLNKSSELNERQRLIIESKIDNRSIIVDQIAGLIARRIVCNVSEGQQVNSGERFGIIRFGSRVNLYLPLNTHISVFKGQTVIGGETILAYLQDAPKQLTVKSI
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PDXT_STAS1
Sequence: MKIGVLALQGAVREHIHHIELSGHEGVAIKRIEQLEEIDGLILPGGESTTLRRLMNLYGFKEALQQSTLPMFGTCAGLIVMAKQISGEDGYLDKLDITVQRNSFGRQVDSFESELDVKGIAEDIEGVFIRAPHIEATHGDVDVLSTVGDKIVAVQEGRYLGVSFHPELTDDYRVTQYFIEAIVKPTLTEKV
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: NUOC_PARP8
Sequence: MASKLETLKANLEAAFGGRLTSITESIGELTIVVKADDFLEVATRLRDDAKLHFEQLIDLCGIDYQTYGEGAYDGPRFAAVLHLLSITNNWRLRVRVFAPDDDVPLIPSVVEIWNSANWYEREAFDLYGIVFEGHPDLRRILTDYGFIGHPFRKDFPVSGYVEMRYDPEEKRVVYQPVTIEPREITPRVIREDRYGGLKH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C, NADH dehydrogenase I subunit C, NDH-1 subunit C.
What is the protein family that this protein belongs to?
Belongs to the complex I 30 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NEUG_CAPHI
Sequence: MDCCTESACSKPDDDILDIPLDDPGANAAAAKIQASFRGHMARKKIKSGERGRKGPGPGGPGGAGGARGGAGGGPSGD
What is the function of this protein?
Acts as a 'third messenger' substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling.  Binds to calmodulin in the absence of calcium (By similarity).
What are the official names of this protein?
Neurogranin, NG, Protein kinase C substrate 7.5 kDa protein, RC3.
What is the protein family that this protein belongs to?
Belongs to the neurogranin family.
Protein: PYRB_GEOUR
Sequence: MAFKHKDIIGLQDLTREEIELLLNTAENLKEINERDIKKVPTLRGKTIVNLFYEASTRTRTSFEIAAKRLSADTINITASTSSVTKGETLSDTARNVLAMKPDIIVMRHAVSGAHHYLAQRVSCSVINAGDGAHEHPSQGLLDMLTMRQKFGKLDGLKVAIVGDITHSRVARSNIYGLTRMGAHVFLAGPPTMMPPGIERLGNVTVCRDMRAAITDADVVMMLRIQLERQGKTLLPTLKEYSRYFGLNNHLLQLAKKDAMVMHPGPINRGVELCSHVADGDQSHILKQVENGVAVRMSMLYHVSGGELPTE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y399_DICNV
Sequence: MLIVTGMSGAGKSVALHTLEDLGYYCVDNLPLILLDAFVRDFAQHHAQPVAVAIDARNAQDISALSDKLQTMKSVTRIQILFLNAQTNVLARRFSESRRPHPLRNFGSEQIIEAIEKERKLLGSLNNIADMLIDTSNYRAADLRQQLMQLLNTTAPHLLITLQSFGFKHGIPVNADFVFDVRFLPNPYWEARLRAFNGKEQPIIDWLEQFAEPRQFAQETAHYLQHWLSYFTGQNNRAYLNIAIGCTGGQHRSVFIAESVGAILRQDFPDLHIEHRDIEKN
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein DNO_0399.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: MUTL_STAAN
Sequence: MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYIKSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKNNLDYVPKKNKVLYSFEQQKIEFEQRQNTENNQEKTFSSEESNSKSFMAENQNDEIVIKEDSYNPFVTKTSESLITDDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNEDASVQNYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.