PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_BURCH
Sequence: MAKRDYYEVLGVAKNASDDEIKKAYRKLAMKYHPDRNPDSKDAEEHFKEAKEAYEMLSDGQKRAAYDQYGHAGVDPNMGGAGAQGFGGFADAFGDIFGDIFGQAAGGAARGGRGGPQVYRGADLRYSMEITLEQAAHGYDTQIRVPSWVSCEVCHGSGAKPGTKPETCPTCHGQGTVRMSQGFFSIQQTCPKCHGTGTYIPEPCAHCHGSGKVKETKTLEVKIPAGIDDGMRIRSAGNGEPGINGGPPGDLYVEIHIKPHSVFERDGDDLHCQMPIPFTTAALGGEIEVPTLAGRASFPVPEGTQSGKTFRLRGKGIKGLRSSIAGDLYVHVQVETPVKLTDQQRDLLKQFEKSLAEGGARHSPQSKSWFDRVKSFFE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_BACCQ
Sequence: MKIALIAHDKKKNDMVSFAYAYKPIFEQHELFATGTTGLRIMEATGLVVTRYQSGPLGGDQEIGAMIAKNDLDMVIFFRDPLTAQPHEPDVNALLRLCDVYAIPLATNMASAEMLMHALERGDLDYRKLRK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: SNMP2_OSTNU
Sequence: MLGKHTKLFFGVSLVALIVSVILAAWGFPKIVSKQIQKNIQIDNSSVMFEKWRKIPMPLTFNVYVFNVTNVEDVNNGAKPRLQQIGPYAYKEYRERTVLGYGDNDTVSYTLKKTFIFDQEASGSLSEDDEVTVIHFSYMAAILTVNDMMPSITGVVNGALEQFFTNLTDPFLRVKVKDLFFDGVYVNCAGNHSALGLVCGKLKADAPQTMRPAGDGNGFYFSMFSHMNRTESGPYEMVRGRENIKELGHIISYKGKSFMKNWGNDMYCGQLNGSDASIFPPIDENNVPGKLYTFEPEVCRSLYASLVGKSSMFNMSAYYYEISSDALASKSANPGNKCYCKKNWSANHDGCLIMGILNLMPCQDAPAIASLPHFYLASEELLEYFDGGISPDKEKHNTYIYLEPVTGVVLKGLRRLQFNIELRNIPMVPQLAKVPTGLFPLLWIEEGAELPDSIIQELRQSHTLLGYVEAVRWALLAIAIVATAISAIAVARSGLLPVWPRNANSVSFILSPHPNSDVNKVH
What is the function of this protein?
Plays an olfactory role that is not restricted to pheromone sensitivity.
What are the official names of this protein?
Sensory neuron membrane protein 2.
What is the protein family that this protein belongs to?
Belongs to the CD36 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSRP_BURP1
Sequence: MLPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFIDSIEKAYDTVRKINDAAQHDGRRPIVFTTLVDGESNEIVKRSNALVLDMFQRFVEPLEQELQLKSSHAMGRVHQNADTEEYKTRIEAINFSLAHDDGQSNRNLADADVILIGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPTPLHPHRDKLFGLSIDPMRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGVKWLSSTHKSIEEIATTILQEIKLERQSY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: ILVR_CAUVC
Sequence: MDIRQFRHFAAVAETLHFGRAAERLGITQPPLSQSIQALEKALGAPLFARTKRHVELTALGRQWLPHVLEALAAVDALPDTARRLRDGQTGYLSLSFVSTADYSVLPDLVRRYAEAFPGVEIQLVEATSDVQVPAIQAGERHAGIIIPPPNRSLPAALAYRRLVSEPLVAVTPEAWGAEGPLDLAALADVPLVLFPRTVAPAFHDLVTGYVAARGQPVRIVQEAIQMQTIISLVSAGLGMALAPASLRKLARVGVRYVDLVDPPILETGLVWRRDEAAPTLQGLLRLVTEDGSAPD
What is the function of this protein?
Positively regulates the expression of the ilvD gene while negatively autoregulating its own expression.
What are the official names of this protein?
HTH-type transcriptional regulator IlvR, Isoleucine biosynthesis transcriptional activator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: TAL_HELPS
Sequence: MQEFSLWCDFIERDFLENDFLKLINKGAICGATSNPSLFCEAITKSAFYKDEIAKLKGKKAKEIYETLALKDILQASSALMPLYEKDPNNGYISLEIDPFLEDDAPKSIDEAKRLFKTLNRPNVMIKVPASESGLEVVSALTKASIPVNATLVFSPKIARKTAQILAKEAQKRAVISVFVSRFDKEIDPLVPKNLQAKSGIINATECYYQINQHANKLTSALFASTGVKSNTLAKGYYIKALCFKNSINTAPLEALNAYLLDPNTEYQTPLKITEIEAFKKELKACNIDLENTAQKLLKEGLIAFKQSFEKLLSSF
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STXB2_PIG
Sequence: MAPSGLKAVVGEKILSGVIRSVKKDGEWKVLIMDHPSMRILSSCCKMSDILAEGITIVEDINKRREPIPSLEAIYLLSPTEKSVQALIXDFRGXPTXTYKAAHVFFTXTCPXPLFSEL
What is the function of this protein?
Involved in intracellular vesicle trafficking and vesicle fusion with membranes.  Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion.  Regulates cytotoxic granule exocytosis in natural killer (NK) cells (By similarity).
What are the official names of this protein?
Syntaxin-binding protein 2, Protein unc-18 homolog 2, Munc18-2, Unc18-2, Protein unc-18 homolog B, Unc-18B.
What is the protein family that this protein belongs to?
Belongs to the STXBP/unc-18/SEC1 family.
Protein: VMA21_MOUSE
Sequence: MERLDKAALNALQPPEFRNENSLAATLKTLLFFTALMITVPIGLYFTTKAYIFEGALGMSNRDSYFYAAIVAVVAVHVVLALFVYVAWNEGSRQWREGKQD
What is the function of this protein?
Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
What are the official names of this protein?
Vacuolar ATPase assembly integral membrane protein Vma21.
What is the protein family that this protein belongs to?
Belongs to the VMA21 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Multi-pass membrane protein.
Protein: UCRI_PROM3
Sequence: MTQMTSSDVPGMGRRQFMNLLTFGSVTGVALGSLYPVVKYFIPPRASGSGGGTSAKDELGNSVTASGWLANHSDGDRSLVQGLKGDPTYLIVEGDDAIGSYGINAICTHLGCVVPWNSGVNKFVCPCHGSQYNSTGKVVRGPAPLSLALANIAVENDNVFVSQWTETDFRTGEKPWWT
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein, ISP, RISP, Rieske iron-sulfur protein.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: DEOD_ECO55
Sequence: MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLFYSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: VATL_TORMA
Sequence: MSTPGAPEYSAFFGVIGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIYGLVVAVLIANSLTEDISLFKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGMILILIFAEVLGLYGLIVALILSTK
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase 16 kDa proteolipid subunit c, V-ATPase 16 kDa proteolipid subunit c, 15 kDa mediatophore protein, Vacuolar proton pump 16 kDa proteolipid subunit c.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: FENR_SHIFL
Sequence: MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPDCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESAIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPGHMTAEHYW
What is the function of this protein?
Transports electrons between flavodoxin or ferredoxin and NADPH.
What are the official names of this protein?
Flavodoxin/ferredoxin--NADP reductase, Ferredoxin (flavodoxin):NADP(+) oxidoreductase, Ferredoxin--NADP reductase, FNR, Flavodoxin--NADP reductase, FLDR.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UQCC2_DANRE
Sequence: MSATRYRRFLKLCEEWPKDESKKGRDLGTFLRQRVASAFREGENTQISDPEKCDQMYESLARINSNVYKEKFPRAKDTSFTGVTVEECRLLLATGSMQQTDEEKKGLWKTLMERFSSKPEDVPPEKAEK
What is the function of this protein?
Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).  May play a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production.  May be involved in cytochrome b translation and/or stability.
What are the official names of this protein?
Ubiquinol-cytochrome-c reductase complex assembly factor 2, Mitochondrial nucleoid factor 1, Mitochondrial protein M19.
What are the subcellular locations of this protein?
Mitochondrion matrix, mitochondrion nucleoid. Mitochondrion.
Protein: HSCB_YERPP
Sequence: MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLGNEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRVAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQQVEQLEERLFDDFA
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: LRTM2_HUMAN
Sequence: MLAPGSSPGQRGRLALQWRQVSWITCWIALYAVEALPTCPFSCKCDSRSLEVDCSGLGLTTVPPDVPAATRTLLLLNNKLSALPSWAFANLSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSIRTLDRDLLRHSPLLRHLDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWECDCNLREFKHWMEWFSYRGGRLDQLACTLPKELRGKDMRMVPMEMFNYCSQLEDENSSAGLDIPGPPCTKASPEPAKPKPGAEPEPEPSTACPQKQRHRPASVRRAMGTVIIAGVVCGVVCIMMVVAAAYGCIYASLMAKYHRELKKRQPLMGDPEGEHEDQKQISSVA
What are the official names of this protein?
Leucine-rich repeat and transmembrane domain-containing protein 2.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SIGA_THET2
Sequence: MKKSKRKNAQAQEAQETEVLVQEEAEELPEFPEGEPDPDLEDPDLALEDDLLDLPEEGEGLDLEEEEEDLPIPKISTSDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLSEITGLDPDLIREVVRAKILGSARVRHIPGLKETLDPKTVEEIDQKLKSLPKEHKRYLHIAREGEAARQHLIEANLRLVVSIAKKYTGRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWIRQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELGREPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGDEKDSFYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSEREAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENKALRKLKYHESRTRKLRDFLD
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_DICNV
Sequence: MMYSKIIGTGGYLPSRIVSNDELSQSMQTSDEWIYSRTGIRQRHLASPDESCSDMAFYAAKRALENAHIEADAIDLIIVATSTPEHIFPSTATVVQSRLSCQRAAAFDVQAACTGFMYALNTADCFIKSGQYQNVLVIGAEVFSRIVDWQDRNTAVLFGDGAGAVVLSASEEAGILGTILHADGSHKELLWVPQGIGSSETDFATRRPFIEMQGREVFKFAVRSLTHLVSELLVQCQMSADEIDFLIPHQANSRIIQAVAEHLNLPIEKVIITVNQHANTSAASVPLALDYGVQNGIIKRGDNLLLEAFGGGFTWGGCILTY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_CARHZ
Sequence: MKIYNTLTKTKEEFIPREPGKVYMYVCGPTTYNYIHIGNARPIVFFDTVRRYFEYKGFEVIYVQNFTDIDDKIINRALEEGISPIELGQKYIIEYFKDADRLGVKRATVHPKVTEHIPEIIEMVKGLIEKGYAYEVEGNVYFAVDSFSDYGKLSGRDLEELKAGARVEVDEKKKNPLDFALWKKAKPGEPYWESPWGPGRPGWHIECSAMSLKYLGENFDIHGGGADLVFPHHENEVAQSEAFTGKPFARYWMHNGFITVNQEKMSKSLGNFFLVREILEKFPGRVVRFFLLSTHYRSPLDFDDKKLNEAKAALERVDNFVQNLKEVNPLPGEARIEIQEKITNFLRDFNEAMEDDFNTAQAMASLFELVRFGNTQIASGNLTAGDKKLFEEALNVYTQVFGIEFGVLEKIAGEDITPFVELLIEVRARLKKEKKYDLADFIRDELKKQGIILEDTPKGVRWKRV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_PSET1
Sequence: MDKYAVFGNPIKHSKSPAIHKQFAISLGEQIDYRAILAPIDNFEKTVSNFFAQGGKGANVTMPFKEQAFAMADELTPLAKIVGAVNTLKKQADGTLLGDNTDGIGFVSDLLANNVSITGKRILIIGAGGAARGVVLPLLDHQPQEVVIVNRTAEKAQNLAKLFAQHGNVSGYGFNNLPENDYALIINSTSSSMNDELPALDQKHITNCEVAYDMFYSLQNTIFMNWVAQYNSKTKLLDGSGMLVGQAAQAYYVWRNKMPAILPVVNALKQGALT
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: NUOA_MYXXD
Sequence: MTPTPLTPYLPLAVVLLLAGGMAMLIPQITTRLGPRRPSAIKATSFEAGSESSGPARQRFAVKFYVVALLFIVFDVEAVFLYPWAVNFQALGWFGYVEMLVFAVTLVVGLIYIWKKGALDWES
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GET4B_XENLA
Sequence: MAAAMAEQEGSKGSARNRGGVQRVEGKLRASVEKGDYYEAHQMYRTLFFRYMSQSKHIEARELMYSGALLFFSHSQRNSAADLSMLVLESLEKHEVKVTEELLENLAKLFSLMDPNSPERVAFVSRALKWSTGGSGKFGDPKLHQFLAITLWKEQNYYESRYHFLHSSDGEGCANMLVEYSSSRGYRSEVDMFVVQAVLQFLCLKNKTSASVVFTTYTQKHPSIERGPPFVQPLLNFIWFLLLAVEGGKLTVFTVLCEQYQPSLKRDPMYNEYLDRIGQLFFGLPPKQSSSYGGLLGNLLNSLMGSGEDDDVEDGQEDSSPIELD
What is the function of this protein?
As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation.  The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane.  Similarly, the bag6/bat3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum.  The bag6/bat3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome.  It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome.
What are the official names of this protein?
Golgi to ER traffic protein 4 homolog B.
What is the protein family that this protein belongs to?
Belongs to the GET4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL23_HAES1
Sequence: MIQQERLLKVLRAPHVSEKATNNTEKSNTIVFKVALDANKVEIANAVEQLFEVKVDSVRTVVVKGKTKRRGAKMGQRSDWKKAYVTLQEGQSLDFVEGAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: URE3_BURMS
Sequence: MKLTPREKDKLLIFTAALLAERRRARGLKLNYPETVAFITAALMEAARDGRTVAEVMHYGTTLLTRDDVMEGVPEMIPDIQVEATFPDGTKLVTVHHPIP
What are the official names of this protein?
Urease subunit gamma, Urea amidohydrolase subunit gamma.
What is the protein family that this protein belongs to?
Belongs to the urease gamma subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOCS3_DROWI
Sequence: MLGVEALRNERSRLRQEIADLRSAICKKEQSLRELEEALANGGGNGDGLADEGGERNTGTIQTQLTNDDIARYSRQLILPNFGVQGQLRLKNSSVLIVGMGGLGCPAAQYLAAAGVGYLGLIDYDQVERSNFHRQTLHTEARCGMAKTESARIALLELNPSCRIHCHSELINSHNASNIMRSYDVVLDCSDNVATRYLLNDACVIFRKPLVSGSALKMDGQLTVYNYGAQGPCYRCIYPVPPPPEAVTNCGDGGVLGAVTGVIGSLQALETIKIIVGGLGEVLAGRMLIFDGTTGQFRNIRIRSKRSNCHACSSQPLITDLIDYELFCGMHATDKDHPLQLLESDQRLDVQTYHDKLESQPHLLFDVRSTAEFEICQLSTNAINLPLAEVLDDSYLKRFAVELQNKDLPIIVLCRRGNDSQIAVQHMRNRFPDHSIRDLIGGLHAWTRKVDPDFPIY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Also essential during biosynthesis of the molybdenum cofactor.  Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A.  Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase MOCS3, Molybdenum cofactor synthesis protein 3, Ubiquitin activating enzyme 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RAB28_RAT
Sequence: MSDSEEESQDRQLKIVVLGDGTSGKTSLATCFAQETFGKQYKQTIGLDFFLRRITLPGNLNVTLQVWDIGGQTIGGKMLDKYIYGAQGILLVYDITNYQSFENLEDWYSVVKTVSEESETQPLVALVGNKIDLEHMRTVKPDKHLRFCQENGFSSHFVSAKTGDSVFLCFQKVAAEILGIKLNKAEIEQSQRVVKADIVNYNQEPMSRTVNPPRSSMCAVQ
What are the official names of this protein?
Ras-related protein Rab-28.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium basal body. Note=Expressed in the basal body and ciliary rootlet of the photoreceptors.
Protein: GLMU_STRT2
Sequence: MSHYAIILAAGKGTRMKSDLPKVLHKVSGITMLEHVFRAVSVIEPAKNVTVIGHKAELVREVLDGQSAFTMQTEQLGTGHAVMMAEEELAGLEGQTLVIAGDTPLITGESLKNLIDFHVNHKNVATILTATADNPFGYGRIIRNENGEVTKIVEQKDANEFEQQVKEINTGTYVFDNKRLFEALKNINTNNAQGEYYLTDVISIFRENGEKVGAYILRDFEESLGVNDRVALATAEDVMRRRINKTHMINGVTFQNPNATYIDVDVEIAPDVVIEANVTLKGQTKVGAESVLTNGTYIVDSTIGANTVITNSMIEHSVVEKGATVGPFAHIRPDSMLKEGVHIGNFVEVKGSTIGENTKAGHLTYIGNAEVGSDVNFGAGTITVNYDGQHKFKTQIANNAFIGSNSTLIAPLEIGDNALTAAGSTITDNVPADSVAIGRSRQVNKEGYAIKKPHHPSQQK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T191C_HUMAN
Sequence: MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKVPPASPPPDLGRCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVLLTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT
What are the official names of this protein?
Transmembrane protein 191C.
What is the protein family that this protein belongs to?
Belongs to the TMEM191 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.