PharMolix/UniProtQA huggingface dataset:
Protein: CCA_SHESA
Sequence: MKIYLVGGAVRDSLLNLPIKDKDFMVVGATPEQMQQLGYRQVGKDFPVFLHPKTQQEYALARTERKVGLGYGGFSCYASPDVTLEQDLLRRDLTINAIAQDEAGNLYDPYHGIADINARQLRHVSAAFAEDPLRVLRVARFAARFHDLGFEIAAETMALMQHMSQTEELTALTPERVWQEVDKSLGGPHPEVFFEVLRQCGALNILFPEIEALFGVPQPEKWHPEIDTGLHTMLVLAQASSLTEEKAVRFAALVHDLGKALSPKEHWPKHHGHGQKGLPVIKSLCERLRIPNEYRDLALLVSDQHQNVHQAFELRSETIIKLFDKADFWRKPERLEQLLLACIADMRGRTGFEHHAYPQGDYLSACFSAASSVDVKAIIAAGFQGAQIKQALNSKRIEVVEQVKLNWQQSQTKQTP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: DNLJ_ACIBS
Sequence: MAITSVIEQMRQLIQLIAKHNHAYYVMDQPTISDSEYDHLFHQLKALEEQYPEFVQADSPTTKVGGQALSKFESVTHVVPMLSLGNVFNQEDLFAFARRVEERLPNQKVQYEVELKLDGLAISLWYENGVLVRGVTRGDGETGEDITQNVKTIRNLPKVLHSEKYEIPRLLEVRGEVLMPKSGFEKLNADQEAKGEKTFANPRNAAAGSLRQLDPNIAAARPLAFYAYGIAQCEPNHGLTTMHDSLQWLTELGFQIAERQYLCNSIQEVQQRYEQIQQERPNLQVEIDGMVVKVDDLKQQQQLGFLSREPRWATAYKFPAQAALTTVEQIDWQVGRTGTLTPVARLNPVFVGGVTVSNVTLHNIGEIHRLDVRIGDTVSVYRTGDVIPKVEKVWPEFRPAEAEVVHLPESCPVCASPVVMPEGEALARCSGGLYCAAQRIEAIRHFVSRKAMDIEGLGDRWVESLLRLDLLKDVADIYHLHEHRETLLGIEKMGEKSVQNLIDAIEASKKTTLARFIYALGIRGVGETTARMLANTFQTLEALKAANVEALKKTPDVGDITAEWIADFFLAPHNIEVLDRLIAAGIHWDAPTAPTRQPLNGESWVLTGTLEQMTRDQATQMLQALGARVSGSVSSKTKCVVAGEKAGSKLEKAAKLGIPVMNETDFLSLMAGYGQTLS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: COPB_STAEQ
Sequence: MNHSNQMHHDNHESHNHHSGHAHHHGNFKVKFFVSLIFAIPIILLSPLMGVNLPFQFTFPGSEWVVLILSTILFFYGGKPFLSGGKDEIATKKPGMMTLVALGISVAYIYSLYAFYMNNFSSATGHTMDFFWELATLILIMLLGHWIEMNAVGNAGDALKKMAELLPNSAIKVMDNGQREEVKISDIMTDDIVEVKAGESIPTDGIIVQGQTSIDESLVTGESKKVQKNQNDNVIGGSINGSGTIQVKVTAVGEDGYLSQVMGLVNQAQNDKSSAELLSDKVAGYLFYFAVSVGVISFIVWMLIQNDVDFALERLVTVLVIACPHALGLAIPLVTARSTSIGAHNGLIIKNRESVEIAQHIDYVMMDKTGTLTEGNFSVNHYESFKNDLSNDTILSLFASLESQSNHPLAISIVDFAKSKNVSFTNPQDVNNIPGVGLEGLIHNKTYKITNVSYLDQHGFEYDNDLFIKLAQQGNSISYLIEDQQVIGMIAQGDQIKESSKQMVADLLSRNITPVMLTGDNNEVAHAVAKELGISDVHAQLMPEDKESIIKDYQSNGNKVMMVGDGINDAPSLIRADIGIAIGAGTDVAVDSGDIILVKSNPSDIIHFLTLSNNTMRKMVQNLWWGAGYNIVAVPLAAGILAFIGLILSPAIGAILMSLSTVIVAINAFTLKLK
What is the function of this protein?
Involved in copper transport.
What are the official names of this protein?
Probable copper-transporting P-type ATPase B.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y021_BACC1
Sequence: MMRGGMGNMNNMMKQMQKMQKEMAKAQEELGEKTVEGTAGGGMITVIANGHKQILEVKVKEEVVDPEDIEMLQDLVLAATNDALKKADELSNSTMGKFTKGLNLPGGMF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BCE_0021.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PSAJ_PROMM
Sequence: MRKFFESWPMAAVLWVWLTAGIIVEFNRFYPDLLFHPMGL
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: MSRA_ECO8A
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TFDF1_CUPPJ
Sequence: MKKFTLDYLSPRVVFGAGTASALPDEIGRLGARRPLVLSSPEQRELAKDIVRPIGDRVAGYFDGATMHVPVDVIQKAERAFNDTDADSIIAIGGGSTTGLAKILSMNLDVPSLVIPTTYAGSEMTTIWGVTEGGMKRTGRDPKVLPKTVIYDPLLTVDLPLAISVTSALNAIAHAAEGLYSADLNPVLETMCKQGICALFDAIPRLVAKPTDAEARTDALFGAWMCGTALCHLGMGLHHKLCHTLGGTLNLPHAETHAIVLPHALAYNLPYAAPAERLLQEVAGSSDVPSALYDLARNAGAPLSLAEIGMRPEDIPRVRDLALRDQYPNPRPLESDALETLLVNAFRGRRPDFK
What are the official names of this protein?
Maleylacetate reductase 1, Maleylacetate reductase I.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: ARF6_XENLA
Sequence: MGKMFSKIFGNKEMRILMRGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFNVWDVGGQDKIRPLWRHYYTGTQGLIFVVDCPDRDRIDEARQELHRIINDREMRDAIILIFANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCAASGDGLYEGLTWLTSNYKS
What is the function of this protein?
GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling.  May modulate vesicle budding and uncoating within the Golgi apparatus.  May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity).
What are the official names of this protein?
ADP-ribosylation factor 6.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Lipid-anchor. Endosome membrane; Lipid-anchor. Recycling endosome membrane; Lipid-anchor. Cell projection, filopodium membrane; Lipid-anchor. Cell projection, ruffle. Cleavage furrow. Midbody, Midbody ring. Golgi apparatus. Note=Distributed uniformly on the plasma membrane, as well as throughout the cytoplasm during metaphase. Subsequently concentrated at patches in the equatorial region at the onset of cytokinesis, and becomes distributed in the equatorial region concurrent with cleavage furrow ingression. In late stages of cytokinesis, concentrates at the midbody ring/Flemming body. After abscission of the intercellular bridge, incorporated into one of the daughter cells as a midbody remnant and localizes to punctate structures beneath the plasma membrane (By similarity). Recruited to the cell membrane in association with CYTH2 and ARL4C. Colocalizes with DAB2IP at the plasma membrane and endocytic vesicles. Myristoylation is required for proper localization to membranes (By similarity).
Protein: TOLB_LEGPA
Sequence: MCNRIISLFLLLFTGQVIALDLELTQGINSALPIAINSFGSDAAAQEIGNVIENDLTISGQFKIISGPQGANSQSSVSTLRQLGADSVVTGRVNQVGNRIEVSFTLADAVANGNILLTKTFQINANQVRALAHHISDEVYQKLTGERGIFSTRIAYISVQRNGGRSRYSLEVADADGHNPQSLLVSSEPIMSPSWSPNGKSISYVSFEKKKAEIFTVSVETGQRRLITSFPGINGAPAWSPDGRHLAVVLSKSGTPKIYDVDLSSGSMKQLTFGNSIDTEPRYSPDGRSLLFTSGRGGSPQVYRLSLADGQISRVTFEGNYNARASYTPDMKHIVMLHREDRQFNIGVQNTGGGPISNLTFSGLDESPSVSPNSRLVLYATRYQDRGVLGIVSIDGRIRMRLPAREGDVQEPAWSPYLS
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DTD_AERHH
Sequence: MIALIQRVSEASVTVEGEMTGAIGQGLLVLLGVEQGDDEAKADKLLHKVSGYRIFSDENGKMNLNVSQAGGGLLVVSQFTLAADTNKGMRPSFSGGAHPVEAERLYDYFVAQAAASGIPTATGRFAADMKVALVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPKA_PYRFU
Sequence: MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLLHMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKNDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVEALEGKTGTQVLP
What is the function of this protein?
Carbamate kinase that plays a biosynthetic role in that it produces carbamoyl-phosphate.
What are the official names of this protein?
Carbamate kinase, Carbamate kinase-like carbamoylphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_ACISJ
Sequence: MTDRLTPRRAAPRQPALLPLADRCTALLSRLSHADAAGGIVLLIAAAAALAWANSPWAASYHALWHVPLSVAVGGWQLTQSLHFWVNDALMTVFFLVVGLEIRRELHDGVLAQPRDALLPVLAALGGVAVPALLYLALVPPALRSGWAVPTATDIAFAVGVLALLGRGLPPVLRVFLLTLAIIDDLVAVLIIALFYSGGLQWPMFGIAALGLAGVLLLQQLGVRRAWAYVPAGAVLWWGIWQTGAHPTLAGVVLGLVTPVHALAGREPAPPVQRVQASLHPWVTFGVMPLFALANAGVALGSAGGAQPAAPGTGLLMAAVAVALVAGKPLGVLLACWLAVRLRLCALPAGMGWGGLLLTGLLAGIGFTMAIFIATLAFDSAALLDAAKRGVLLASGLAALLGLAWGWWLQRRATTA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RASEF_MOUSE
Sequence: MAQEVSSSVAFIHRLLYTALRGLLGDRLKRGLKKEQVSTLYQNITLVEPRLLQPYERVIRNFLREIKLQSTEMENLAIAVKRAQDKAAIQLSELEEEMDQRIQAVENESRKDEKRKAEEALTDLRRQYETEVGDLQVTIKRLKKLEEQSRQISQKQDVTALKKQIHDLTMENQKLKKELLEAQTNVAFLQSELDALKSDYADQSLNSERDLEIIREYTEDRSSLERQIEILQTANRKLHDSNDGLRSALENTYSKLNRSLRINNISPGNTISRSSPKFNHHSSQPLAYDRSFHSSYADEDCDSLALCDPLQKMNYEVDSLPESCFDSGLSTLRDNECDSEVDYKHQGEFQTLHRTEESLGGDASDTDVPDIRDEEAFDSESVASVLHWQPQGSAGEGSTLSSSRKPISALSLQTDMVDNTSKVTSQKAYKIVLAGDAAVGKSSFLMRLCKNEFQGNTSATLGVDFQMKTLIVDGEQTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNVREWVDMVEDGTHRTIPIMLVGNKADLRDVDNAENQKCISAYLGEKLAMTYGALFCETSAKDGSNVVEAVLHLAREVKKRTEDDDSRSITSLAGSTSKKSLQMKNCCNG
What is the function of this protein?
Binds predominantly GDP, and also GTP (By similarity).  Acts as a dynein adapter protein that activates dynein-mediated transport and dynein-dynactin motility on microtubules (By similarity).
What are the official names of this protein?
Ras and EF-hand domain-containing protein homolog.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region.
Protein: MYF5_XENLA
Sequence: MEMVDSCHFSPSEFFYDSSCIPSPEEGYTEDYEHGMSIYGAHKKDLEESDEDEHVRAPIGHHQAGNCLMWACKACKRKSSTTDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPKVEILRNAIQYIESLQDLLREQVENYYSLPGQSCTEPGSPMSSCSDGMSDCSSPQWSGRNSSFDNVYCSDLQTSFSSTKLTLSSLDCLSSIVDRISSPQQCSLPIPDSITPSPTSSTDSLPRSPDAHDCRPIYHVL
What is the function of this protein?
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.  Induces fibroblasts to differentiate into myoblasts.  Probable sequence specific DNA-binding protein (By similarity).
What are the official names of this protein?
Myogenic factor 5, Myf-5.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL11_METB6
Sequence: MAEVVEVLVPGGKATAGPPLGPALGPLGINVKAVVDEINAKTASFNGMQVPVKVEVNDKKQFTVTVGIPPTTALIKKEANIEKGSAEPNAKVAGNLPFEAAVRIAKMKLEGMLSYELKTATKEVVGTCVSMGVNVDGKRPKEVLADIAAGKYDSVLLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: DNAA_NEIG1
Sequence: MTLAEFWPLCLRRLHDMLPHGQFAQWIAPLTVGEEGGVWVVYGKNQFACNMLKSQFAGKIEAVREELAAGRPAFVFKPGEGVRYEMAAVEGAVEPAEPSLHAGSEEMPVQEVLLDELPSEKPVKPAASKTAADILAERMKNLPHEPRQAAGPASRPESAAVAKARTDAQRDAEEARYEQTNLSPDYTFDTLVEGKGNRLAAAAAQAIAENPGQSYNPFFLYGSTGLGKTHLVQAVGNELLKNRPDAKVRYMHSDDYIRSFMKAVRNNTYDVFKQQYKQYDLLIIDDIQFIKGKDRTMEEFFYLYNHFHNEKKQLILTCDVLPAKIEGMDDRLKSRFSWGLTLELEPPELEMRIAILQKKAEAAGISIEDEAALFIANLIRSNVRELEGAFNRVGASSRFMNRPVIDIDLARTALQDIIAEKHKVITADIIIDAVAKYYRIKISDVLGKKRTRNIARPRQVAMSLTKELTTLSLPSIGDSFGGRDHTTVMHGIRAVAKLREEDPELAQDYEKLLILIQN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TMM42_HUMAN
Sequence: MAERPGPPGGAVSATAYPDTPAEFPPHLQAGAMRRRFWGVFNCLCAGAFGALAAASAKLAFGSEVSMGLCVLGIIVMASTNSLMWTFFSRGLSFSMSSAIASVTVTFSNILSSAFLGYVLYGECQEVLWWGGVFLILCGLTLIHRKLPPTWKPLPHKQQ
What are the official names of this protein?
Transmembrane protein 42.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RGF1B_MOUSE
Sequence: MPQTPPFSAMFDSSGYNRNLYQSAEDSCGGLYYHDNNLLSGSLEALIQHLVPNVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCVEHQRLSEGDGDKNQMRKIAPKILQLLTEWTETFPYDFRDERMMRNLKDLAHRMASGEEQTYRKNVQQMMQCLIRKLAALSQYEEVLAKLSSTATDRLTVLKTKPQSIQRDIMTVCSDPYTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKSCYSERKKTRNLEAYVEWFNRLSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILEHQMDPSSNFYNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCVNRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKVLQYLLSVPVFSEDALYLASYESEGPENNIEKDRWKSLRSSLLGRV
What is the function of this protein?
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, it doesn't seems to activate other Ras family proteins (in vitro).
What are the official names of this protein?
Ras-GEF domain-containing family member 1B, GPI gamma-4.
What are the subcellular locations of this protein?
Early endosome. Late endosome. Midbody. Note=Localizes to midbody at telophase (By similarity). May shuttle between early and late endosomes. Does not colocalize with lysosomal markers.
Protein: RL7_PROMP
Sequence: MTAKTEEILDSLKSLSLLEASELVKQIEEAFGVSAAASAGVVMAAPGAGGGDGDGGAAEEKTEFDVILESFDAAAKIKVLKVVRNATGLGLGDAKALVESAPKTVKEGIAKADAETLKKEIEEAGGKVTLK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PGK_DESAP
Sequence: MLKKTIRDVDIAGKRVFVRVDFNVPFNERGEVADDTRIRAVLPTIEYLLTGGAAVILASHLGRPKGKRDDRFSLRPVADRLSALTARQVRFAAEAVGPETEAASRELAPGDILLLENIRFYPEEEQNDPEFASRLAALADLYVNDAFGTAHRAHASTAGIAAHLPAVAGLLLERELDILGRLLSVPERPFVALIGGAKISDKIGVLERLIEKADYLLVGGGMANTFLAAQGHNLQASLVEADRLETARYLLAKAGPGERITLPIDLVVAPDREQPEKRATVAVESIPAGWAAFDLGSGTVRLYANRLRPARTIFWNGPVGLFEVPGFDRGTLDLARVIAAAEATTVVGGGDTVAAVKQAGVLDQVTHVSTGGGASLKLLEGRELPGVAVLQNR
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MK09_CHICK
Sequence: MSDSKCDSQFYSVQVADSTFTVLKRYQQLKPIGSGAQGIVCAAFDTVLGINVAVKKLSRPFQNQTHAKRAYRELVLLKCVNHKNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIHMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTACTNFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGELVKGCVIFQGTDHIDQWNKVIEQLGTPSAEFMKKLQPTVRNYVENRPKYPGIKFEELFPDWIFPSESDRDKLKTSQARDLLSKMLVVDPDKRISVDEALRHPYITVWYDPAEAEAPPPQIYDAQLEEREHAIEEWKELIYKEVMDWEERSKNGVVKDQPSAQMQQ
What is the function of this protein?
Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity (By similarity).  May play a role in the development of the central nervous system during embryogenesis.  May play a role in the regulation of the circadian clock (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase 9, MAP kinase 9, MAPK 9, Stress-activated protein kinase JNK2, c-Jun N-terminal kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
Protein: GRPB_RAT
Sequence: MLVVLLTAALLALSSAQGTDEEVNNAETSDVPADSEQQPVDSGSDPPSADADAENVQEGESAPPANEEPPATSGSEEEQQQQEPTQAENQEPPATSGSEEEQQQQEPTQAENQEPPATSGSEEEQQQQQPTQAENQEPPATSGSEEEQQQQESTQAENQEPSDSAGEGQETQPEEGNVESPPSSPENSQEQPQQTNPEEKPPAPKTQEEPQHYRGRPPKKIFPFFIYRGRPVVVFRLEPRNPFARRF
What is the function of this protein?
GRP proteins have a marked affinity for hydroxyapatite.  They may play a role in the formation of the protective acquired pellicle at the saliva-tooth interface.
What are the official names of this protein?
Submandibular gland secretory Glx-rich protein CB, GRP-CB, Contiguous repeat polypeptide, CRP.
What are the subcellular locations of this protein?
Secreted.
Protein: MIS_RAT
Sequence: MQGPHLSLLLLLLATMGAVLQADTVEELTNTRGLIFLEDGVWPPSSPPEPLCLVAVRGEGDTSKASLTVVGGLHSYEHAFLEAVQESRWGPQDLATFGVCSTDSQTTLPALQRLGAWLGETGEQQLLVLHLAEVIWEPQLLLKFQEPPPGGASRWEQALLVLYPGPGPQVTVTGAGLQGTQSLCPTRDTRYLVLTVHFPAGAWSGSGLALTLQPSKEGATLTIAQLQAFLFGSDSRCFTRMTPTLVLLPPTGPTPQPAHGQLDTVPFPQPGLSLEPEDLPHSADPFLETLTRLVRALRGPLTRASNTRLALDPGALASFPQGLVNLSDPVALGRLLDGEEPLLLLLSPAAATVGEPMRLHSPTSAPWAAGLARRVAVELQAAASELRDLPGLPPTAPPLLSRLLALCPNDSRSAGDPLRALLLLKALQGLRAEWRGREGRGRAGRSKGTGTDGLCALRELSVDLRAERSVLIPETYQANNCQGACAWPQSDRNPRYGNHVVLLLKMQARGAALGRLPCCVPTAYTGKLLISLSEEHISAHHVPNMVATECGCR
What is the function of this protein?
Plays an important role in several reproductive functions.  Induces Muellerian duct regression during male fetal sexual differentiation and plays a role in Leydig cell differentiation and function (By similarity).  In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles.  AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression (By similarity).
What are the official names of this protein?
Muellerian-inhibiting factor, Anti-Muellerian hormone, AMH, Muellerian-inhibiting substance, MIS.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMD_CHLSY
Sequence: MRFDILTLFPAMFQGPLTESILKRAQQAGRIEIHLHDIRQWTTDRHRTADDTPYGGGAGMVMKAEPLAAAIRAVRAADERPGVTILLTPDGELLTQQIVRELATLPRLLLVCGHYEGIDERVRETLIDRELSIGDYVLTGGELAAMVVVDAVARLVPGVIDSESIVEESHSDFLLEYPHYTRPAVWEGRAVPPVLLSGHHGEIARWRRAERLRRTLVRRPDLLARAAAAGVLTKADLALLAELGWRPETSNGA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPTD_XYLFT
Sequence: MYRVLRLLPLPLSVAISLSALADEKPPNWGLCPATLPLQGFEQAPGMDKHVVQSRPQLPTNIEGDTLTGTARTPLYQGNVLMARGDQLLGADSVRMDTETDSYVAEGHVRYQDSSILVVADRAEGNQDTDVHKISNIQYQLIGRRGNGVAKSVDIHGQVGQTHEATYTTCDPSQAIWRLRAPEIDVDNVEGFGVARHAVFEVGQWPVLYLPWFKFPIDSRRQTGLLYPQLGYSGRNGFDYAQPIYLNLAPNYDATLYPRYMQKRGFMIDTEFRYLYDDGKWQTRAAFIPNDQLRDKDRGRFSFNGYHNIDNHWQARASLAWVSDTRYMEDFSSRLVGMSSLSSLQSTVGVYGTGETWTAGLMADRWQLTDYSLNESALAYNRQPRLFFNWDKPVLDFLEFGLYSEVVRFKHDDAYLVALQNDGNYLRTGEVIRYYGGTRLDVKPYVSLPFTGASWYVTPTFGWRYSSYYLDSGIAEQLNGSRTPVRSLPIVSLDSGVYLDRDTTVFGRNYLNTLEPRFYYLYVPYRNQSDLPLFDTRAFTFSWGQLFRDSRYTGPDRQNDANQLTLAVTSRWLDQNTGKEDLALSVGQILYFKDSLVTLSDSEERIQKGKSVWVSDVAYNVNDRWTLNATYQWNPNFRRDDLASVRARYLIGSDGIINLAYRYRRNTLDGTTQLKQTDFSFLYPINPRWSAIGRYYYSLLDKKPLEIIGGLQWDSCCLAVRTVLRRHMRDRTGNMDNSIQLEFVFKGLSSVGQDTDRVLRRAILGYYRDDLYLVPPSNTTTDPDAYDPNKIP
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: RRAB_SALTI
Sequence: MANPELLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDFETLEKAAVEAFKLGYEVTEPEELEVEEGDTVICCDILSECALNAELIDAQVEQLMNLAEKYDVEYDGWGTYFEDPNGEEGDDDDYVDEDDDGVRH
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity B.
What is the protein family that this protein belongs to?
Belongs to the RraB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BCHL_BRASO
Sequence: MNVTLRPPLAAAPRRPDGAGSVQVQMDPNLVIGTARVFSVYGKGGIGKSTTSSNLSVALSKLGKRVLQIGCDPKHDSTFTLTKRLVPTVIDILEQVNFHSEELRPDDFVYQGYNGVMCVEAGGPPAGTGCGGYVVGQTVKLLKEHHLLDDTDVVIFDVLGDVVCGGFASPLQHADRALIVAANDFDSIFAMNRIVAAIQAKSRNYPVRLGGVIANRSAATDQIDKFNERIGMKTLAHFPDLDVIRKSRLKKCTLFEMEPSPDVERAQNEYLRLAASLLAGVEPIHAVPLKDRDIFDLLGFD
What is the function of this protein?
Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide).  This reaction is light-independent.  The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP.
What are the official names of this protein?
Light-independent protochlorophyllide reductase iron-sulfur ATP-binding protein, DPOR subunit L, LI-POR subunit L.
What is the protein family that this protein belongs to?
Belongs to the NifH/BchL/ChlL family.