Protein: LYST_DROME
Sequence: MAGMEVKEKEEQLLLDTLIGLWSQYLQASELEDASVKDHWLWLLLYNLQFLDDKNLQDAWLNSHFNLMPEELCSYLLEQVYQIISEAKRSQESSPTHEPEQQDKCIKQLRKQHNLAQLILSTPSDCNKILALRTFLTDKLGHHLLTFLLRVDIKLIASQKSLCHLCINLFPNCKWSASNEQLIPMTSIAQFIGSFYLNSQSKKLRRQQQPKSQLPNHISNPIKSSFEDFRGTTRSSDELALLLIQLLTRCVDAEQESQLSVTVHNFALGHLCSSSEQDASGNNDELIKFELLQLIAHCVNNFYVLEQQQPNVHDFNSNFGQLLYALTANRRSPLLAHGVLYIMFGTLHNLVDNGVRELNQIDVRNFDACFEVLQEAAKSTNFSTAIFLHIYKMLLRLTDNLSSQEQHLQSLMESSASTAMPKQQQHPRHKRQRSSQLHCLGATSLSCYFQGKLYHLLPSLEAELQEHSVRSLLRTGSCCCHYNVRNYATCLQLATQLSSSYQKCAYKFLHYNVLHTIFVKRNPQGCPGCEDKLKSPVFHMDLLNIYKDNYKALLNTPAMLLFLKHLKHIAYLLPYDLASGILAEVALPIFRRYKELIESGESKRKISKVTPLQLPSKLENYRALHECLSIFVMYLSDIRLVKAFYNEENIRYMQDLLIIPELQRGVCDLIKVGIDNIAFLGENSQEQITLSRRLIQLQLNSSDRASQLFQALLYKCSKHSRAKFWLDESSTPAKLEGHKPADILYITALQWTLNFELLKTSQLFYNEFAKIYSIPVEMLDDEDEDEVETPTSELLPGEKKLRHGDKNIFDILKLNYNALGCFLMLPKATMGPTTSSTATTPTAGICGSSSLETLVSQLPLAGSTSVSVTTAASSDYADSTLDYASVIGNYDSYSRDMATPSFLQQLLACEPDESTVLFDIRGSQSSKDNPSNSLILPSEEEGATADGIINKLFSIVGSLFGGSPGSGGSANSPTRANIDADFFCLYEPNGECKKLLLKLFEATMAICIKGFQNEEVEKMQKHLRKLRAIILSHATDNWSEHGEQHARDNAVIQTLQTLLKIAELSSTHQEPTGVVNSPSGDSQQPRPRARSFNSGSVELPRLQTVKLPAKNSLATPPTPRRRPNSSEANAGVDADYFSTRASLSCAADSELELSENEHEFYLTADEGYEADGEIADLSESECELNGGVLAANESTWTPFQPSSRYRSHIMHQGLSQLVVQMLAELSLLCIKQPNGWTESLTQLANRLFVIRDYLGGPLCLLKGFAPILSCSDPRLRELQQSILELVTHLNTPEVLQCYYSILASKQPPVDLLMRHMHHISSGSLRKAQPCMELDFPIITDGKIVVTSEPLVSEQIERVRLHHQQCQTNTLFTRAACIFPVTQTRLWQPDGLTLSLWLELRGQQMHRSSMQFNDDETRYSGEDLTKLHLLSLGTNQAMVSIYISNNMQLIFELVKPNEQLAPVRVEEQIEANADTASVISANTQAANGGTIRQALKQTKLALLNSFGQMHLLNGHQASADSTGGYFESSAVQLQHLRLPRHKWMHLVFGLQQQADSVEISIFLDGLEQHTMRLPFRNLRQLTRVHSFQLLALGEGQPTGRSPGSSSSSRSTLDGSTPRYALSNVILFKRRLVDPLLMMNLTAMGPDFTEFTQCQVANWKPNYGFVSLGKLSSSNFGNHLDCMRQLRQARVLVYTAQQPDLVMSYDASQELDMACYGQPHGHMLYGELQQHQAQTLQAATSLSGGLSTLLYLFARIVELTGNASTQALALDLLLQVAHSDAQLYTEFQRQDYLSLIGYVIKSEKCSKDVQLLRSIVNNACSQVLITRKGDSINVNDNTMATLVYPRLMLTVLQRYSDWHRSGATHSDVLDMLFRCILALTRDKHPQRDFNMEQLQKCGLLGALLNLCKVYVIESPSPVQISPYAAECFVQILAVFSGSPPDSSMLDEIMKLLLLLHKPSDCYVTHDRTHFYFLLTAQQPTKERSLVAANLSRVTTSLRRQLHPQPQELDPERAERIKKLRRLHASTSGYRKAVNEFEEHLDQMADCSNLNKSALRLLSPVEATRWRLKFKRRHPTSANSPKRSPLKIARRRIHPHLHLGKIWQPSGHSTPSSGQSSLPNRKTDFYDQLGIIRLQQRLLILLKDFLCLLPDSSVDVVTRHYVKLELLLVLANQRSCAVRQAIIQLVDVLTKRLPSGELNAATKLMHPLHLANQLTIHGCDVGMFEACLAWINGMHCSLTDIQSCDAPVRIRQRFGLPSLLAIAEGTEPQWVFKALLRLYLQNPDDQTCLIEAGLLQCSVKALYKIYSLRVGQSNADESVVELLATIGERAMRSVGQINLVWDILNLLSFYQDKQPQLIMRSFRTAQAQLQLEWLTKFFEPNSFRVAVTNDSSLSHSELRTRVELLIDRCTQFFTVGVGQTTGPNYVASSQELALFQLLVSYGISSNQRCNNFIAWGLQPSRPRDLRSYIVDALWRSQQDEFQRAIICDAKMIKALLWLSLLEDMPEPIENLKPLCDALGIKENDSSWNLVHELDRLDQNRNNMAAKQKTLLEKTVYRFEPLVQQCVESSMVTTRKVAELQNAERKALMCHMKVYDDTYTYTKWLEIIRRMTHEGAPWHSAERAECSWELDDTEGPSRVHTRLRRCHLDIDRRFFMNEYRPGQGHREDLEPYVRPLDYLIASYDQQLNISLNSQILYNFAAKFLPVDGEIEGEIIITDLKLYFLATYRCRYFNVNCDIANITEIWLKRYQHQETAFEILLDTNKSLFFSLQNADDWKIMREVFCDKIVATPDQSKVIAITQQWREGLLTNWEYLMTLNQISGRTYNDLMQYPVFPWVLANYNSEVLDLREGHNFRRLGRPIAVQVEENEKHYISNYTYIDSTNTTMGSLILKPYHYSSHYSNSGTVLHFLVRVPPFTSYFLRYQDNDFDLPDRTFHALNTTWLLASRDSPTDVKELIPEFFCLPEMFENFERFKFGCRQNGERVEDVSLPPWSQRDSRLFVLIHRQALESELVRNQIHNWIDLIFGYKQSGESAVEAINVFHPATYAVFLDSEISDPIEREAVKTMVKTYGQMPRQLFKSPHPASKPLDYSLVGKPIVSTVRGLRWGVYVGSPQLKAPSWANIHKIPGTEHLVSFCNTNVVYALPGRASVMQGAEPDTYNVISWGYDDRIVRIQPLNKPQAKPKNLLHNGTFDDITACGCDVNSNQLWFGHKSGRISVYKCTGGLDSQQRASAKSRQSYARGFSLSYNSAFRKMTNKGIGGGGSERVDEAGNLHPTSSASSVNSSSISSGGDAFQRDGADLNWLGPTLLVRHTDEITCITLSVEFKIAVTAGRDGIAVIWDLNDWSYVRTIARPAEIHQSPITHVAISPTLGDIVTVHTLPQSCNTSTDPKPTAVATRPNSLNVADECFEVTEENLDDFVNVNVNPNGKSILRLHSVNARYVQHLVHEDRILAVCYSYIKEGVGVNVIATAVEGGFVRFWSSWNLSFVSELTTGTSPIRSICYSTHQHLVVLTRESHIQVWESEGLYGNAPKFPQIVYK
What is the function of this protein?
Adapter protein that regulates intracellular membrane fusion reactions (By similarity) (PubMed:33725482).  Regulates the fusion of lysosome-related organelles (PubMed:33725482).  Promotes microtubules nucleation and centrosomal recruitment of microtubule nucleating proteins such as msps (PubMed:33725482).  In syncytial embryos, during the formation of yolk granules, suppresses vesicle fusion events with lipid droplets, possibly via interaction with Rab5 (PubMed:33725482).  In the eye, regulates pigment granules size (PubMed:22934826).  In hemocytes, required for the late steps of bacteria phagocytosis (PubMed:22934826).  In fat body, required for autophagosome maturation (PubMed:22934826).
What are the official names of this protein?
Lysosomal-trafficking regulator, Mauve protein.
What are the subcellular locations of this protein?
Vesicle. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Associated to yolk granules during vitellogenesis.