PharMolix/UniProtQA huggingface dataset:
Protein: CCD39_CANLF
Sequence: MSSELLEELHWDDGFAIPVANEENKMLEDQLSKLQEERASLQDQLRDYEDRINAMTSHFKNVKQEFSFTQSLCKAREHEIESEEHFKIIAERELGRIKDEIQRLENEMTSIREKKSDKENNIFKTTQKLDGLKCQINWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTLECNQRRKVLDNELTETLSAQLELDKAAQDFRKIHNERQELIKQWENTIEQMRKRDRDIDNGALALARIKQELREKENLVKEKIKFLESEIGNNTEYEKRISVADRKLLKCRTEYQHHETNRNQLKDELDSLKATVNRSSSDLEALRKNISKIKKDIQEETARLQKIKNHNQSVKKKLKQITEKTMSVEEKATNLEDMLREEEKSVKEVEVQLNIVKDVLFKKVQELQTEAMKEKAVVSEIEGTRSSLKHLNHQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEINSEEKQALETKIVELKKILEEKKSTFDLLESQIKKLHNDLYFIKKSNSKNCDEKQFLMTKVNELNLFNDRSEKELNKTKALKQDLMIEDNLLKLEVKRTREMLHSKAEEVLSLEKRKQQLHTAMEERMEEIKVHKTMLASQIRYIDQERQNLSAEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQAYYVIKAAQEKEELQREGDSLDAKINKAEKEIYALENTLQVLRSCNNNYKQSFQKITPSSDEYELKIQLEEQKRAIDEKYRYKQRQIRELQEDIQSMENTLEVIEHLTNNVKEKLSEKQAYSSQLNRETEEQRPKLERVTKQCAKLTKEIRLLKDTKDETLEEQDIKLREVKHFHKIIDEMLAEVTEENAEIHIILQTYFQQNGLELPTAGTKGSRQSSRSPSQTSLLSARSTTSVASQTSIKVLELNFPASSSVTGNISRPASATTIPSNGKNKKGSK
What is the function of this protein?
Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella.  Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella.  Not required for outer dynein arm complexes assembly.
What are the official names of this protein?
Coiled-coil domain-containing protein 39.
What is the protein family that this protein belongs to?
Belongs to the CCDC39 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Note=CCDC40 is required for localization to axonemes.
Protein: FABZ_YERPN
Sequence: MTTDTHTLHIEEILDLLPHRFPFLLVDRVLDFEEGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSRGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVEFVKERRGLTRFTGVAKVDGEIVCTATMMCARSKPAAPAESVVVKPDVVKPDVVNPVVKES
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBJL_ECO57
Sequence: MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLSLGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG
What are the official names of this protein?
Putative transport protein YbjL.
What is the protein family that this protein belongs to?
Belongs to the AAE transporter (TC 2.A.81) family. YbjL subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AAC6_MORMO
Sequence: MDSSPLVRPVETTDSASWLSMRCELWPDGTCQEHQSEIAEFLSGKVARPAAVLIAVAPDGEALGFAELSIRPYAEECYSGNVAFLEGWYVVPSARRQGVGVALVKAAEHWARGRGCTEFASDTQLTNSASTSAHLAAGFTEVAQVRCFRKPL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring including tobramycin and netilmicin and to a lesser extent to gentamicin and amikacin.
What are the official names of this protein?
Aminoglycoside N(6')-acetyltransferase type 1, AAC(6')-I, Aminoglycoside resistance protein.
Protein: DNAA_CUPNH
Sequence: MQDFWQAAAAQLERELTPQQFKTWIKPLAPVAFDEETHALRIAAPNRFKLDWVKSQFSGRITALACEYWEAQVSVQFVLDPAASGRAAAYMQPAQPGMGPGGMDGHAAPGTGMGGYPGAQPMGGQAMGQPPFAMPGQQPGYGYGEPVSAAGYGMGQPPYGNPGNPGNPAGMPSAAPVPAGARGQPHPGQHGHQPHGADMGEIDVVQMDPAEASARSYRAPPQQPQQQPHQQMGGATPMPGHQPSDTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIHAIGNFMLLENPRARIRYIHAEQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVIITSDTYPKEISGIDDRLISRFDSGLTVAIEPPELEMRVAILMKKAAAENVNVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGKDITIEVTREALKDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIADERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADI_SHIF8
Sequence: MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLAHVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSDGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPARSTPLALERAGLTMSELTLIDMHEAFAAQTLANIQLLGSERFAREVLGRAHATGEVDDSKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRL1A_BOVIN
Sequence: MSSLPRGFEPQTPEDLGQRSLAELREMLKRQERLLRNVKFICKLPDKGKKISDAVTKLKAAIAEREEVRGRSELFYPVSLDCKERQKAIAVVDGDRDKAQNSDQILDTSSPVPGCSSVANITSSQTTSRQQGLAHPTRGGDAEAAEAEHTVSEHPTSSSGAPAPSSSQASEGLPQHCALGQVEDHPGSSDNLFIDRLQRITIADPTEHHSEGNRNPENLAGLWSGPQKKPHYMEVLEMRAKNPMPPPHKFKTNVLPSQPRDSSSACQRRGSPISSEERRRRDRKHLDDITAARLLPLHHLPTQLLSIEESLALQRQQKQSYEEIQAKLAAQKLAERLNIKMQSYNPEGESSRKYREVRDEDDDQSSEDEF
What is the function of this protein?
Appears to be a stable component of the Pol II(G) complex form of RNA polymerase II (Pol II).  Pol II synthesizes mRNA precursors and many functional non-coding RNAs and is the central component of the basal RNA polymerase II transcription machinery.  May play a role in Mediator complex-dependent regulation of transcription activation.  Acts in vitro as a negative regulator of transcriptional activation; this repression is relieved by the Mediator complex, which restores Pol II(G) activator-dependent transcription to a level equivalent to that of Pol II.
What are the official names of this protein?
DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit M, GRINL1A downstream protein 1, Gdown1, Glutamate receptor-like protein 1A.
What is the protein family that this protein belongs to?
Belongs to the GRINL1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNLJ_CLOB6
Sequence: MDNKLEKMKKLVEELNQYAYEYYVLDNPSISDKEYDLKYDELVILEKETQVTLPYSPTQRVGDKILGEFSKYTHKGRLWSLDKAQNMEQLIEWHNRNLKVIEQYNSMSEDKLPELRYIVTKKFDGLTVNCTYDENGILIKSATRGTGIIGEDITAQIKTIKTVPLKIKNNHVIEVHGEAIMTKTAFEEYNKAAQVPLKNLRNGAAGALRNLDIKETARRNLSAFFYDVGYNEGPEFKSYREMMNFIRNMGLPQDKYIKECTNMEEVEKEIEYIESIREELDYDIDGAVIVVDDIKTREILGYTIKFPKWAIAYKFEAKEITTKLLDVEWNVGRSGRVTPTALLEPVELGGVTVKRATLNNMDDIKRKNVKLGAKVLVRRSNDVIPEIMGVVEESLEESKEIQAPDRCPYCNSHLVQNGVHYYCENTLSCKPQMVKSIVHFASREAMNIAGFSGKTAEQLFERLDIKSISDLYKIRKEELLTLDKFGDKKSQNLIDAIENSKNCDLASFIYALGIPNVGKKTANDLVMKFKTLESIKNTTIEQLVEVPDVGEIVAKSIYDFFEDEKIISNIEELLNLGVKPYYEEERIDENPFMGKTIVVTGSLNNYSRGEIKDKLQSLGAKVSSSVSKNTDYVLVGEKPGSKYEKAIELGVKVINEEEFSNKIK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ERA_PSEPG
Sequence: MTDNNPTRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGDVQAIYVDTPGMHKANDKALNRYMNRNASAALKDVDVVIFVVDRTKWTDEDQLVLERVQYVTGPLIIAVNKTDRMEEKAELIPHLQWLQEQLPNAEVMPISAQQGHNLDALEAQIAKHLPENDHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGHVLHIHALILVERDGQKKIIIGDKGERIKRIGSEARKDMEVLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: APT_BRUSU
Sequence: MESGFKVTLKDAIRTIPDYPKPGVQFRDVTTLMGNAQAFRRAVDELVYPYAGNRIDKVAGIEARGFILGGAIAHQLSAGFVPIRKKGKLPRDTVRIAYSLEYGVDEMEMHRDAIEKGERVVLVDDLIATGGTAEAAAKLLLQMGAEIVAACFIIDLPDLGGRKKLEALGLPVRTLVAFEGD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCC4_DROAN
Sequence: MSASTSTTAAASQDACYISLLGLAEYFRTSQPPNIKKCIQCLQALFTFMPPSKVEARTHLQMGQILMAYTQNIDLARHHLEKAWSISEPLANFDVKFDTASLLAQLHLQTDQNSNQAKAMLRRAVELSQHNVYWHCKLLLQLAQIHASDREYSLASDLLAVGAENADEAGATYLKVLFLLSRAMILMIERKTNDVLALLNSAGQIIDNNIPNPHQKEYLKVFFLVLQVCYYLALGQVKTVKPSLKQLQMSIQTIMAPNWPSDETIFGANQLEMFVWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKQQEDKPILSVFKVILLEHIVMCRMVMGNRELAIREIAAARDVCLAAPQRSLLRRHSAQLHCLIGLYSMSTSFFEHAERQFLVCVSETNERDLKLFANLNLAIIYLRTKRDTDLKQILDAVSSENTNTYSSQALMGGFYYVQGLHAFHKNSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTPAMQLASKIPDIHVQLWGSAILKDLHRMSKDAQHEKDAYANHLKYSENLIADQRKSVQSSHHELVNWFHGDPPVTSGPPTTTAVAMILPDSSAAVGPVPVIASTSTGMQQAIQPVGQYGQFY
What is the function of this protein?
Required for association of the cohesin complex with chromatin during interphase.  Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity).
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, Cohesin loading complex subunit SCC4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Binds to chromatin from the end of mitosis until prophase.
Protein: FLGH_SHEFN
Sequence: MIKYIALASVVLLVGCSSTAKKPIADDPFYAPVYPDTVPTQVAATGSIYLDSQASSLYSDIRAHRVGDIITVTLKESTQASKSANNEIKKGSDLSVEPVYAGGKNISISGVPIDLGYSDSMNTKRESDADQSNSLDGSISANIIQVLSNGNLVIRGEKWISINNGDEFIRVTGMIRSEDINPDNTIDSTRVANARIQYSGTGTFADSQKVGWLSSFFMSDWWPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: ARGB_LAWIP
Sequence: MDMEKARLRSHMLIESLPYLQKFQGKVIVIKYGGHAMKDTLLKQSFAQSIALLNLVGIHPIVVHGGGPQIGNMLSRLNIQSEFREGLRVTDKATMDVVEMVLAGSVNKEIVNQVNQAGAKAVGLSGKDGAFILAEKNDLILTKENQPPEIINLGNVGRVVHIETSLLYTLIEKGFIPIIAPVGTDNKQTYNINADEVAGAIAGALKATRLLLLTDVEGILDLNKKLIQSIYLEDTPKLFSDGIVFGGMIPKLQCCIEAIEQGVEKVVILDGRLEHSILLELFTDQGVGTEIVKKPV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF2_METPB
Sequence: MAEQNILTTPSPNADTTIVPPGSPHTHTEQPSGGHGGAFPPFESHTFLAQLIWLALAFGLLYYLMSKVALPRIEAILGDRAGRLSSDLNEAQRMKAEADAAGAAYETSLREAQAKAQAIAQETRNSLSAEADAKRKTLEAELNQRLAASEATIRARTSEAMGNVRTIAGETASAIVERLTGQAPDQASLNRALDATPAVH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: DDX52_DROME
Sequence: MDEHDIFKLITAGVRFTKKSKKEPSSKQQLQPLPEVSKHEEPVKSEESDKDDEDITEFRLLDGDSSNQPKRKKPKKEKTLSPKELEIQKAAEEANETRKQYGIRVLGKNVPPPVDSFGTLTRDFKMLPRLQQNLLSRNFDHPTPIQMQALPVLLQRRALMACAPTGSGKTLAFLTPIINGLRAHKTTGLRALVLAPTRELAQQIYRECAELTRETGLRTHFISKVSEAKQKHGAECKQRYDILVSTPNRVRFLLQQEPPLLDLSHVEWFVLDEADRLMEEGQNNFKEQLDDIYAACSNPTKCVAFFSATYTVPVAKWALRHLKNLVRITIGVQNSATETVQQELLFVGSEGGKLVAIRDLVRQGLQPPVLVFVQSKERAKQLFEELLYDGINVDVIHAERSQHQRDNCVKAFREGSIWVLICTELMGRGIDFKGVNLVINYDFPPTTISYIHRIGRTGRAGRPGRAITFFTQEDTSNLRGIALIIKNSGGTVPEYMLQMKKVRKSEAKMRAKKPLDREDISTKIRPETKGDEKHKSTKLKKVERTEKILKNRKGYEKDLNSKQKKLGNIKTELKPAGKRKGNVEKKTKNKNNQT
What is the function of this protein?
Part of a translational control module, also containing pths/DDX47 and ath/DHX33, which coordinates germline stem cell differentiation with ribosome biogenesis during oogenesis.  This module allows for coregulation of ribosomal proteins and non1/GTPBP4, a p53 repressor, preventing p53 stabilization, cell cycle arrest and loss of stem cell differentiation (PubMed:35413237).  Controls cell cycle progression by regulating translation of mRNAs that contain a terminal oligo pyrimidine (TOP) motif in their 5' UTRs, such as non1 (PubMed:35413237).
What are the official names of this protein?
DEAD box protein 52 homolog, ATP-dependent RNA helicase DDX52, Protein aramis.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
Protein: PYRC5_PYRCO
Sequence: MASKSQILFIGGTGYIGKFIVEASAKAGYPTYVLVREASLSDPAKSKVIENFKALGVNFVLGDLYDHESLVKAIKQVDVVISTVGHGQLADQGKIIAAIKEAGNVKRFFPSEFGNDVDRSHAVEPAKSAFETKAKIRRAVEAEGIPYTYVSSNFFAGYFLPTLNQPGASSAPRDKVVILGDGNPKAIFNKEDDIGTYTIRAVDDPRTLNKVLYIRPPANTISFNELVSLWEKKIGKTLERIYVPEEQLLKNIQEAAVPLNVILSISHAVFVKGDHTNFEIEPSFGVEATALYPDVKYTTVDEYLNQFV
What is the function of this protein?
Oxidoreductase involved in lignan biosynthesis (PubMed:11606193).  Catalyzes the NADPH-dependent reduction of phenylcoumaran benzylic ethers (PubMed:11606193).  Converts dehydrodiconiferyl alcohol (DDC) to isodihydrodehydrodiconiferyl alcohol (IDDDC) (PubMed:11606193).
What are the official names of this protein?
Phenylcoumaran benzylic ether reductase Pyrc5, Minor fruit allergen Pyr c 5.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: CATA2_NICPL
Sequence: MDPSKFRPSSAYDSPFLTTNAGGPVYNNVSSLTVGPRGPVLLEDYHLIEKLATFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVVHERGSPESLRDIRGFAVKFYTREGNFDLVGNNVPVFFNRDAKSFPDTIRALKPNPKSHIQEYWRILDFFSFLPESLHTFAWFFDDVCLPINYRHMEGYGVHAYQLINKAGKAHYVKFHWKPTCGVKCMTEEEAIRVGGTNHSHATKDLYDSIAVGNYPEWKLSIHIMDPEDVERFDFDPLDVTKIWPEDILPLMPVGRLVLNRNIDNFFAENEQLAFNPGHIVPGLYYSEDKLLQTRIFAYADTQRHRIGPNYMQLPVNAPKCAHHNNHRDGAMNFMHRDEEVDYLPSRFDPCRHAEQYPIPSRVLNGRREMCVIEKENNFKQAGERYRSWEPDRQDRYVSKWVEHLSDPRVTYEIRSIWISYLSQADKSCGQKVASRLTLKPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 2.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: KDSA_ECOUT
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGNEKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKGFEELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_BACAN
Sequence: MHYPEPISKLIDSFMKLPGIGPKTAVRLAFFVLDMKEDDVLGFAKALVNAKRDLAYCSVCGHITDRDPCYICNDSHRDQSVVCVVQEPKDVIAMEKMKEYQGVYHVLRGAISPMGGIGPEDINIPQLLKRLHDETVQEVILATNPNIEGEATAMYISRLLKPTGIKVTRIAHGLPVGGDLEYADEVTLSKALEGRREV
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RAD50_CAEEL
Sequence: MAKFLRLHIRGIRSVGDEDHDVHKIDFLSPCTLISGPNGTGKTTTIEALNFVTTGQMPTQKKQNFIHSTDVARKTRVDASVTLEFIDVKGRECTAVRRLVVTSGTKAAALAEEHTLAIKYPDGTVNTLSSKVCDFNTALLKHLGVPRAVFKYVIFCHQEDSTWPLSEPKELKKRFDDIFQLTKFVKAQERMKKIVLDFKKEMQTHEMSKQLYETHVRDKLVARQNQEECERKISKRKEETDELKERKANGQKKIEEMRTSIHELEDTLTSFKKTELERQNLKKQLSLIRVEPYFGTEEELKREIEEFRGSEGRSYGEERARIQKKIGKNNQERQELSQKKTEFENRISSLKAEVIHCQSLKYDLERLENQLRSELDLEHDADIDIEIDNAITLKIRGMSDKARMIAKNCAELQSNLRTAQEAATKIEVEMKTLQNEKVKLEKEVEQLKFKIKQGQNATAGMKDLLKKEEALRKSLADLPLLDENALTECKLKREKYLKQLDILKKKCAEAEKNAEKDREKESLKQTLSIARKKMTAYQRIYDNNWQGLIGQAPDFPWTPILSKTFHKLRNDKKIMEEDLRDVQLNVQKLETMQHQYRKQEESLTAQELKLSENIFEACSCEAEEVSEKLENLRKRLKKARKDLAPLSAKSNLYDSYIEESKSSGCCPLCDRDFKTKKEINEFSKKLENMTLSFPTEQEELEKLVSKLEKEEIIIVKAEGQANELQRIVKELKEVREKNRKLSTEMAEEKSNLSKNEKQLETVNAKLKLAEDLQTDVGVIQQLYEQTEENEKRYEQLVSESDSSDGLSYTELRKKVEDKDEEYRKIVQEGEELQKCSEERNKLQSKLNELGTHRVSLGEAAAQAGAFAEQLETKIKEIQECITAISQKRNEDLPDAQFKKDDLTRNVSSKEEEKKKAEMEVQMMKKELDQKIFHRKSLFKKVQEGGLCERQLMDKENNIATLNASLEENQQRQKRFEEDLRSFDSSHQRESILKDQLTRMIIENKIKELKRTLATFDGQINEDRITEQKQAYNKLQNELRLIGNEEVKIYTQMQEYEKQKKIAEAKLSTKECQNAESNYRDAIIELAITKESISDLTKYRNCLDASLIQFHSEKMGRVNGIIDDLWRKVYNSTDITTIRIRSDATSETSSKKVAYEYNVMMVHETGTEVEMRGRCSAGQKMLASLLIRIALAEVFGGSCSMIALDEPTTNLDESKVEGMAIVLADIIAERRGFDENGKLRGRDMQMVVITHDERLVNRITISCRPEYIYCLGKDEHGISFLSKRYPDGTVKRVNTKRRF
What is the function of this protein?
Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis.  In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity.
What are the official names of this protein?
DNA repair protein rad-50.
What is the protein family that this protein belongs to?
Belongs to the SMC family. RAD50 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAC_MYCLE
Sequence: MVRMNEVFDCADPDQRARGIASAVAALKGGRLVVMPTDTVYGIGADAFDRAAVAALLSAKGRGRDMPVGVLVGSWHTIEGLVYTMPDGARELIRAFWPGALSLVVVHAPSLNWDLGDAHGTVMLRMPLHSVAIELLCEVGPMAVSSANVSGQPAAVDVDGARGQLGELVGVYLDAGPSAQQAASTIVDLTEATPRILRAGPVSVARIAEVLGVVPASLIA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Putative threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, tRNA threonylcarbamoyladenosine biosynthesis protein ML1136.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LMBD1_MAGO7
Sequence: MAPYLQTSLIWIAYAVAVGLALFAAIVTTFTWQKPRERSAVVNTVAVVSLTSLLATVLLLPVDIALVSSTGSVHLGVNKEWATPEHVAGMLRTLQIVYYSLYSLDALLCLIVIPFAYFWYEEYDEVEEEEGTRSTGAKLWGAFKYTSGFIILVLILFFVGFFVPAAGNQKGGHLDLDYFKRLLAANKGEKALTFAVGLLVCLGTLLYVLYTSSGLALLPISFIKSAPSISAPQLSETTASALERNRERQRQLELRNGGNHDEMPSKDRRELESLVREERTLVRRARLAAEAQGEGRSWVYRTWTKICAVFRPLKLVGGILLLLVSVIVWVSMLITTIDKASNSLCKGHCGYILGQIKIFQPVNWLFLQAAKAFPVDYIIMAFLVLFFFSSSISGLATVGIRFLWVQIFQIRRGRTAPQAILIATVMMALIILGINYSIAMMAAPQYSIYGTQTFCTAEPTAHGKQPDCSEHPEMVRPCSEGFKQPLAKDICTPSVMSTFLNRVTLNWPVFGAVDFWAQVAFLAVFLIVLVTSLFRTPKLNMSELDEEAEADEEEGLLASTGRRFGATWQDITGRSGQASNQENGDN
What is the function of this protein?
Probable lysosomal cobalamin transporter.  Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity).
What are the official names of this protein?
Probable lysosomal cobalamin transporter.
What is the protein family that this protein belongs to?
Belongs to the LIMR family. LMBRD1 subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: SECA_KINRD
Sequence: MPAIVEKVLRAGEGRVVKRLHRVAEQVNALESDFEAMNDEELRGETVRFRERLAAGETLDDLLPEAFAVVREAARRTLGQRHFDVQLMGGAALHQGNIAEMRTGEGKTLVATLPAYLNALSGKGVHVITVNDFLAEYQSELMGRVYRFLGLTSACILSRMRPDERREAYAADITYGTNNEFGFDYLRDNMAWSTAEMVQRGHNFAIVDEVDSILIDEARTPLIISGPSDSPTKWYGEFAKIARRLTVDVDYEVDEKKRTIGILEAGIEKVEDLLGIENLYESVNTPLIGFLNNAVKAKELFKRDKDYVVSPNDEVLIVDEHTGRILAGRRYNEGMHQAIEAKEGVPIQNENQTLATITLQNFFRMYDKLAGMTGTAMTEAAEFHQTYKLGVVPIPTNRPAVRVDQPDLVYKNEQAKFAAVVEDIAEHHAAGQPVLVGTTSVEKSEYLSTLLTKAGVEHTVLNAKQHEREASIVAMAGRKGAVTVATNMAGRGTDIILGGNAEFLAVQAMRDKGLDPDETPEDYEAAWPEVLEQAQASVKAEHDEVRDLGGLYVLGTERHESRRIDNQLRGRSGRQGDPGESRFYLSLTDDLMRLFNAALVESFLTRTGIPEDVPIESKMVSRAIQSAQGQVEGRNFEIRKNVLKYDDVLNRQREVIYAERRKVLEGEDLHLQIRHFIDDVVTAYVTEATARGFGEDWDLDELFEALRSLYPVSVTPEEVVEAAGGRGNLTVERLLEEMRADAQACYDAREQELGETVVRDLERRVVLSVLDRKWREHLYEMDYLQEGIGLRAMAQRDPLVEYQREGYQLFGAMTEAIKEESVGYLFSLQVQPAAQAGAAATPPGFGAPPVRQQLQYSAPTAEGDVEVHAGDAAATDADTGNRAQRRANQRQQREV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.