PharMolix/UniProtQA huggingface dataset:
Protein: PROA_TREPA
Sequence: MVEVYARLRAAVARLAVCSAAEKDGALRAVRDALHAQREDILRANAQDLARAREAGLAAPLVARLALSEHLLEDMLRSLTVLSLQRDPIGEIIEGYTLANGLEIRKVRVPLGVVAVIYESRPNVTVDAFALAYKSGNAVLLRAGSAASYSNAPLLRAIHVGLKKAHGVVDAVAVPPVLEEKYGDVDHILRARGFIDAVFPRGGAALIRRVVEGAHVPVIETGCGVCHLYVDESANIDVALQIAENAKLQKPAACNSVETLLVHRAVARPFLHRVQEIFATCEETTRKPGGVDFFCDAESFSLLTERGARKNVFHAQAETWDREYLDYQVSVRVVPNLEEALRHIARHSTKHSEVIVTRDRARARRFHQEVDAACVYVNASSRFTDGGQFGMGAEIGVSTQKLHARGPMGLCALTTSKYLIDGEGQVRP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRB4_ARATH
Sequence: MGNQKLKWTAEEEEALLAGVRKHGPGKWKNILRDPELAEQLSSRSNIDLKDKWRNLSVAPGIQGSKDKIRTPKIKAAAFHLAAAAAAAIVTPTHSGHSSPVATLPRSGSSDLSIDDSFNIVADPKNAPRYDGMIFEALSNLTDANGSDVSAIFNFIEQRQEVPPNFRRMLSSRLRRLAAQGKLEKVSHLKSTQNFYKMNDNSLVQRTPHVARPKESNTKSRQQTNSQGPSISQQIVEASITAAYKLVEVENKLDVSKGAAEEIERLMKLAEEADEMLVIAREMHEECSQGKIMYLN
What is the function of this protein?
Binds preferentially double-stranded telomeric repeats.
What are the official names of this protein?
Telomere repeat-binding factor 4, MYB transcription factor.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family. SMH subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS2_WIGBR
Sequence: MLNLSMKDMIQSGVHFGHQTRYWNPNMKPFIFCKKNKVHIINLEKTLIMFEIAMNELSKISKRDGKILFIGTKRAASEAIKNSAINCNQFFVNYRWLGGMLTNWKTVRQSIKRLKELESQSKDGTFKKLTKKEALIRTRTLNKLENSLGGIKNMGGLPDAIFVIDVEHEKTSIKEANKLGIPIFAIVDTNSNPKDIKFVIPGNDDSIRAIDLYLKTVSETIKNSKISNKEINKKIIIKNN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: FMT_SHISS
Sequence: MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQESQQLVADLQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPITAEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RS20_PSEPW
Sequence: MANTPSAKKRAKQAEKRRSHNASLRSMVRTYIKNVVKAIDAKDAEKAQAAYVLAVPVIDRMADKGIIHKNKAARHKGRLNGHIKALKEAAAA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS22B_CANAL
Sequence: MTRTSVLADALNAINNAEKTGKRQVLIRPSSKVIIKFLTVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVIQPRFNVKINDIERWTDNLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY
What are the official names of this protein?
40S ribosomal protein S22-B.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ASZ1_ECHTE
Sequence: MAASSLWGPAVAGGGESSESEDDGWEIGYLDRAPQKFTAPLPAEEKNEMFKKALTTGDTSLVEELLNAGISVDSSFRYGWTPLMFAASIANVNLVRVLLNRGANASFEKDKQTVLMTACSARGSQEQIIKCVELLLSRNADPNVACRRQMTPIMYAARGGHPQVVALLVAHGAEVNAQDENGYTALTWAAYQGHKNVILKLLELGANKMLQTKDGKTPSEIANRNKHPEIFSLLSLTLNPLEGKIQQLTKEETICKMLATDCDKEKDNLFSSYTAFGELDLFLHGLGLEHMTDLLKERDISLRHLMTMKKDEFLKNGITNKDQQKILSALKELMVEEIKFGELPEVAKLEISGDEFLNFLLKLNKQCGHLITAVQNIITELPVNSHKIVLEWASPRNFTSVCEELVTNVEGLSEEVCRLKDLIQKLQNERESDPTHIPLVEEVSPWKSRLLKRTAVTVCGFGILLGICKLMFQRKLL
What is the function of this protein?
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons.  Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process.  Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons.  May act by mediating protein-protein interactions during germ cell maturation (By similarity).
What are the official names of this protein?
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1, Germ cell-specific ankyrin, SAM and basic leucine zipper domain-containing protein.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. Specifically localizes to pi-bodies, a subset of the nuage which contains primary piRNAs (By similarity).
Protein: PTN23_HUMAN
Sequence: MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQEAVGQAGAISITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAFRGQLGDVGALDTVWRELQDAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLRATRPSDDPLSLLDPLWTLNKT
What is the function of this protein?
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes (PubMed:18434552, PubMed:21757351).  May act as a negative regulator of Ras-mediated mitogenic activity (PubMed:18434552).  Plays a role in ciliogenesis (PubMed:20393563).
What are the official names of this protein?
Tyrosine-protein phosphatase non-receptor type 23, His domain-containing protein tyrosine phosphatase, HD-PTP, Protein tyrosine phosphatase TD14, PTP-TD14.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasmic vesicle. Endosome. Cytoplasm, cytoskeleton, cilium basal body. Early endosome.
Protein: RL15_BURO0
Sequence: MELNNLKPAAGAKHAKRRVGRGIGSGLGKTAGRGHKGQKSRSGGFHKVGFEGGQMPLQRRLPKRGFTSLTKEFVGEVRLSDLEKLPVDEIDLLALKQAGLVGELTKSAKIIATGELKRKIVVKGLGATKGARAAIEAAGGSFAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RSMI_MYCTO
Sequence: MSSGRLLLGATPLGQPSDASPRLAAALATADVVAAEDTRRVRKLAKALDIRIGGRVVSLFDRVEALRVTALLDAINNGATVLVVSDAGTPVISDPGYRLVAACIDAGVSVTCLPGPSAVTTALVISGLPAEKFCFEGFAPRKGAARRAWLAELAEERRTCVFFESPRRLAACLNDAVEQLGGARPAAICRELTKVHEEVVRGSLDELAIWAAGGVLGEITVVVAGAAPHAELSSLIAQVEEFVAAGIRVKDACSEVAAAHPGVRTRQLYDAVLQSRRETGGPAQP
What is the function of this protein?
Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase I, 16S rRNA 2'-O-ribose C1402 methyltransferase, rRNA (cytidine-2'-O-)-methyltransferase RsmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_FRAAA
Sequence: MLRSVVLAGGGTAGHVEPALAVADALRAADPRARLTLLGTATGLEARLVPARGYELATVPKVPMPRRPTPALLKLPVRLFDAVRQAGATLDRVRADVVVGFGGYVSVPAYLAARRRGIPIVVHEANPLPGMANRLGARFTPFVATSYPSTPLRGATLTGIPLRAEILSLDRSPAAARAARARYGLDPHRPTLLVFGGSQGARSLNQVMTTAAHSLATAGVQVLHAAGPKNFEEVAAALPRGLPAPYELRPYLDDIMSAYAAADMTLCRSGAMTCAELAAVGLPAAYVPLPHGNGEQRRNALPTVEAGGGLLVEDAALDEDWLLANVLPVLTSAERLAKMSAACAGTGYPQAAAAIVAMVRDAAATRRRSRPRHAAS
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL34_BACC4
Sequence: MKRTYQPNKRKRSKVHGFRSRMSTANGRKVLAARRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: LS14A_MOUSE
Sequence: MSGGTPYIGSKISLISKAEIRYEGILYTIDTENSTVALAKVRSFGTEDRPTDRPIPPRDEVFEYIIFRGSDIKDLTVCEPPKPQCSLPQDPAIVQSSLGSSSSSFQSVGSYGPFGRMPAYSQFSPSTLVGQQFGAVGVAGNSLTSFGTEASNSGTLSQSNAVGSAFTQDTRSVKPQLAQGRSSPQLDPLRKSPTMEQAVQTASAHLPAPAPVGRRSPVPARPLPPTSQKAIDNQEHRRAEVHKVPRPENEQLRNDKRQVVPGVPSAPRRGRGGHRGGRGRFGIRRDGPMKFEKDFDFESANAQFNKEEIDREFHNKLKLKEDKLEKQEKPVNGEDKGDSGVDTQNSEGNADEEDPLGPNCYYDKTKSFFDNISCDDNRERRPTWAEERRLNAETFGIPLRPNRGRGGYRGRGGLGFRGGRGRGSGRGGTFTAPRGFRAGFRGARGGREFADFEYRKTTAFGP
What is the function of this protein?
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for translationally inactive mRNAs and protect them from degradation.  Acts as a repressor of mRNA translation.  May play a role in mitotic spindle assembly.
What are the official names of this protein?
Protein LSM14 homolog A, Protein FAM61A, RNA-associated protein 55A, mRAP55A.
What is the protein family that this protein belongs to?
Belongs to the LSM14 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm, cytoskeleton, spindle. Cytoplasm, Stress granule.
Protein: RS20_HUMAN
Sequence: MAFKDTGKTPVEPEVAIHRIRITLTSRNVKSLEKVCADLIRGAKEKNLKVKGPVRMPTKTLRITTRKTPCGEGSKTWDRFQMRIHKRLIDLHSPSEIVKQITSISIEPGVEVEVTIADA
What is the function of this protein?
Component of the small ribosomal subunit (PubMed:23636399).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399).
What are the official names of this protein?
40S ribosomal protein S20, Small ribosomal subunit protein uS10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_BRAHW
Sequence: MGAMDLVFKLIFGSKEQNDAKILKPIAEKTLTFEEEIKKLSNEELTNKTKEFRERVEKYIGCKTEELDLSKEENKKKLQNILDEILPEAFAVVREASIRTTGMRHFDVQVMGGAVLHQGRIAEMKTGEGKTLVATLAVYLNALTGLGVHVVTVNDYLAKRDAEWMTPIYSMLGISVGILDNTRPHSPERRAVYNCDVVYGTNNEFGFDYLRDNMVTRKEDKVQRKFYFAIVDEVDSILIDEARTPLIISGPAEKNIKMYYEIDRIIPMLKQAEVDERMREVAGTGDYVLDEKDKNVYLTEEGVHKVEKLLNVENLYGAQSSTIVHHVNQALKAHKVFKKDVDYMVTDGEVLIVDEFTGRVLEGRRYSDGLHQAIEAKEKVAIQNESQTYATITFQNYFRMYPKLSGMTGTAETEAEEFYKIYKLDVAVIPTNKPIARQDLSDRIYRTRKAKFEALAKYIKELQDAGKPALVGTVSVEMNEELSKVFKRHKINHEVLNAKNHSREAAIIAQAGEPGAVTLATNMAGRGTDIVLGGNPVAKGVAEIEQILVLMRDKAFKERDPYKKEELTKKIKSIDLYKEAFVRSVISGKIEEAKELAQKNNADEMIEKIDRIIQINEKAKVDKERVLAAGGLHVIGSERHEARRIDNQLRGRSGRQGDPGLSVFFLSLEDDLMRLFGGERVSKMMLAMGMGEEEELGHKWLNKSIENAQRKVEGRNFDIRKHLLEYDDVMNQQRMAVYGERDYILYSDDISPRVEEIISEVTEETIEDISGNKKNVDALEVTKWLNSYLIGIDEDAANKAVEGGVDNAVKNLTNLLLEAYRKKASEIDEKIFREVEKNIFLSIIDNRWKDHLFAMDSLREGIGLRGYAEKNPLTEYKLEGYKMFMATMNVIHNELVNLIMRVRIIPNSFDTIERESAFDGGVEEKSSASAMNGGNAQAIQSKVKNAQPNVKMAQKIGRNDPCPCGSGKKYKHCHGKDNPQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: ATPL_SULTO
Sequence: MKKTWLPFLLLPLLVSATIFSAQAPYDTAQGFEGLNIGAGLAIGLAAIGAGVAVGMAAAAGIGVLTERRDMFGTILIFVAIGEGIAVYGILFAVLMLFGKF
What is the function of this protein?
The C chain is a proteolipid, and one of the membranous subunits of the nonenzymatic component of the Sul-ATPase complex.
What are the official names of this protein?
Membrane-associated ATPase C chain, Sul-ATPase proteolipid chain.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEMA_RINDK
Sequence: MSPPRDRVDAYYKDNFQFKNTRVVLNKEQLLIERPCMLLTVLFVMFLSLVGLLAIAGIRLHRAAVNTAKINNDLTTSIDITKSIEYQVKDVLTPLFKIIGDEVGLRTPQRFTDLTKFISDKIKFLNPDKEYDFRDINWCINPPERIKIDYDQYCAHTAAEDLITMLVNSSLTGTTVLRTSLVNLRRNCTGPTTTKGQFSNISLTLSGIYSGRGYNISSMITITGKGMYGSTYLVGKYNQRARRPSIVWQQDYRVFEVGIIRELGVGTPVFHMTNYLELPRQPELETCMLALGESKLAALCLADSPVALHYGRVGDDNKIRFVKLGVWASPADRDTLATLSAIDPTLDGLYITTHRGIIAAGTAIWAVPVTRTDDQVKMGKCRLEACRDRPPPFCNSTDWEPLEAGRIPAYGVLTIKLGLADEPKVDIISEFGPLITHDSGMDLYTSFDGTKYWLTTPPLQNSALGTVNTLVLEPSLKISPNILTLPIRSGGGDCYTPTYLSDRADDDVKLSSNLVILPSRDLQYVSATYDISRVEHAIVYHIYSTGRLSSYYYPFKLPIKGDPVSLQIECFPWDRKLWCHHFCSVIDSGTGEQVTHIGVVGIKITCNGK
What is the function of this protein?
Attaches the virus to cell receptors and thereby initiating infection.  Binding of H protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity).  Down-regulates human MCP/CD46 cell surface expression.
What are the official names of this protein?
Hemagglutinin glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family. Non-sialidase subfamily.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host membrane; Single-pass type II membrane protein.
Protein: THIC_NITHX
Sequence: MNIRSNPDTTRPAVTTGALPSSRKIFSVPEAAPDLLVPLREIVLSEGAGEPNLPVYDTSGPYTDPDVTIDVNAGLPRTRLAWVKERGGVEEYDGRVIKPEDNGNVGASHAATAFKAHHKPLRGVGDAPITQLEFARAGIITKEMIYVAERENIGRKQQLERAEAALADGESFGAAVPTFITPEFVREEIARGRAIIPANINHAELEPMIIGRNFLVKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCDGDPVKLTWELYRDTLVEQCEQGVDYFTIHAGVRLPYIHLTADRVTGIVSRGGSIMAKWCLAHHKESFLYTHFEEICDLMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTQIAWNKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPNRDDVKTGVITYRVAAHAADLAKGHPAAQLRDDALSRARFDFRWQDQFNLGLDPETAVAFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLGDNEKAALYPEGSKLASGMTMKGVIEDGMTQMSEKFKEMGGQVYVEAEAVKESNKVL
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: GTAD_DICDI
Sequence: MSINHFNNNKNNNNKNNKNNEENFWDNTQCNNDRNKFSIDNIINSNYPTANTTTITSTTNQTIQNNVLNSINIKNNESLKNIYYDENLQRKLTSINFLKNLCSVRDQPFNFNEHIKSIQSINSYRKCISNEIFKKNLINNQLSDILIIIEITSFIGDCIFEIFYLNYFQETLEKDILLFSNASETICIPSHHSPSPQFPVYYTENINNATPSTVVSNSPNNYSQPISPQSSQSTTPTIISSNSPLKTRNKNNNNNYNNNNNNNNNNNNNNNNNNNNSNNNNNNNNYFNNNKKNKIGDCNSNNSNNNNNNNHNNNNNNNNYNYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNKNNNNINNNNNNNNNNNNNINNNNNNNSINNIINNNNNFNNNNINNNLFNNNSMNYNKKENYNWESSSSEEDNNNLIKEQSVKKNETVKKQYIPRKSKYVNYERIKKVSLSKSVEPFDTMKRMEKKKPGNCSMCNIKESISWIKTMVNGQLCNACGLKAIRQIKIEN
What are the official names of this protein?
GATA zinc finger domain-containing protein 4.
Protein: BMT1_CANAL
Sequence: MDKFIQSFSHQYLDSSSSLKLTARRKRKLTILGLFLFSLISLMIIISYSNNNILPGLSGISISSTFSDYYSNPKQQNKFEQQIQDHQTTKKGKRTIIFPNNFNHVHDHKGSYMMKDSELVKYYVETMEQALDPEDLIYRNRFTYKLPNIPYTEQKIEMFSDGGGGGGDTSDSNTDMCPKLSTTIKVEASPAMNKNGDLKKILKTFLQEDSFYYRELSPFFPDLKKHFDEDTIDKHWYQFIGSTVWLEQYGVHLMVSRIIYTEKDQGSPKFSLAYLQVFDRNWKELDNVELIVPDPENISTTNNKNKNKKPYGYKSVLYPTIAPIPVYHNSKQTGGRFYGIEDPRIVLIKTRHGYEEPVLIYNSHHRKISEKHFDNDQEGKINFNNYRSLFIGWIWQTQLGKIHLEELPNNEFKKNEYIKIKEFVKPNNNRGRTEKNWALFINYNQRLNQGFDSHVYFANQLKNLKILKCSILNDNDDDCEWEFQMDDYEDAGVLHGGTELININQLLHQYDYPELNSIKDLIPNGREYWVGFARASLKNCGCGSRMYRPNLIVLMKDGKNYKFAYVSSFVGLGIEILPWYLDKGLCEHYNLIIPNGISSWTIEKDLHQKEKDKQVMDYMAFTISRRDATVDVVYVKGLLKALFTDSSSSKHLLAVEQTGFKSVTNVDCALKNSEKFCKIYGETF
What is the function of this protein?
Beta-mannosyltransferase involved in cell wall biosynthesis.  Required for addition of the first beta-mannose residue to acid-stable fraction of cell wall phosphopeptidomannan.  Plays a key role in reducing host inflammatory response.
What are the official names of this protein?
Beta-mannosyltransferase 1, WRY family protein 4.
What is the protein family that this protein belongs to?
Belongs to the BMT family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RPB2_PICGU
Sequence: MSDQASDPYMYDDDSSSITPEDCWTVISSFFQEKGLVSQQLDSFDEFIESTIQELVWEDSRLILDQPAQHTSEEDHENRRYEITFGKIYISKPTQTEGDGTTHPMFPQEARLRNLTYSSPLYVDMTKRVLKSDDNAGNEHELEWIEEEIKDEEPSTKVYLGKVPIMLRSKFCMLRDLGEHEFYELKECPYDMGGYFVINGSEKVLIAQERSAANIVQVFKKAAPSPISHVAEIRSALERGSRLISSMQIKLYGREEKSTSNRTIKATLPYIKEDIPIVIVFRALGIVPDGDILEHICYDANDWQMLEMLKPCVEEGFVIQEREVALDFIGRRGALGIKREKRIQYAKDILQKELLPNITQDEGFETRKAFFLGYMVNRLLLCALERKEPDDRDHFGKKRLDLAGPLLASLFRILFKKLTKDIYNYMQRCVENDKVFNLTLAVKSQTITDGLRYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGRDGKIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLMSCISVGTPSEPILYFLEEWGMEPLEDYVPSNSPDSTRVFVNGVWVGTHREPAHLVDTMRSLRRRGDISPEVSIIRDIREKEFKIFTDAGRVYRPLFIVDDDPESETKGELKLQKEHIHKLLNAEYSEEYATNEFGEEEGPYGWSSLVNDGVVEYVDAEEEETIMIAMTPEDLEASKSSLTATQQKSLQLEEQELDPAKRIKPTNSSTTSTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYSVRMDTMANILYYPQKPLATTRAMEHLKFRELPAGQNAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRTYMDLEKRQGMKALETFEKPSRSDTLRLKHGTYEKLDDDGLIAPGIRVSGEDIIIGKTTPIPPDTEELGQRTQYHTKRDASTPLRSTESGIVDQVLLTTNGDGAKFVKVRMRTTKVPQIGDKFASRHGQKGTVGVTYRHEDMPFTSQGIVPDLIINPHAIPSRMTVAHLIECLLSKVSSLSGLEGDASPFTDVTAEAVSKLLREHGYQSRGFEVMYHGHTGKKLMAQVFFGPTYYQRLRHMVDDKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKERLMEASDAFRVHVCGVCGLMSVIANLKKNQFECRSCKNKTNIYQIHIPYAAKLLFQELMAMNISPRLYTERSGVSVRT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB2 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB2, RNA polymerase II subunit 2, RNA polymerase II subunit B2.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECO_MYCCT
Sequence: MEKTLKGIVLNSFDFRDYDKIITIYSNLYGKISLVCLGVNKTKSKNKYAINYLSYSNFEIFKAKNKLGLSKLKRSELINSFSHIATDFNLYVYANVLTSLVMNLEDHMKNYNLFKILKLSIFLINSKPNISFKVCILFMFYFLKIIGNQINLTVCGFCNSKINPIIAISFTNYCSSCKFCYFDDCLIIDNQLKNFINSIVKDDFIASLNQKISNQNLKILTKFVLSYYKDQVGIFTTSMYLLSTINQFK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: GLND_ECOSE
Sequence: MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVATNLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGIYSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAWHARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHFTVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRLTEALNPNDKG
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.