PharMolix/UniProtQA huggingface dataset:
Protein: ABHEB_BOVIN
Sequence: MAGVEQREGAIQVQGQSLFFREALPGGGQAARFSVLLLHGIRFSSETWQNLGTLHRLAQAGYRAVAIDLPGLGRSKEAKAPAPIGELVPSSFLAAVVDALDLGPPVVISPSLSGMYSLPFLTAPGSQLRGYVPVAPICTDKINAADYARVKASVLIVYGDQDPMGQTSFEHLKQLPNHRVLVMEGAGHPCYLDKPEEWHTGLLDFLQGLA
What is the function of this protein?
Acts as an atypical protein-lysine deacetylase in vitro.  Catalyzes the deacetylation of lysine residues using CoA as substrate, generating acetyl-CoA and the free amine of protein-lysine residues.  Additional experiments are however required to confirm the protein-lysine deacetylase activity in vivo.  Has hydrolase activity towards various surrogate p-nitrophenyl (pNp) substrates, such as pNp-butyrate, pNp-acetate and pNp-octanoate in vitro, with a strong preference for pNp-acetate.  May activate transcription.
What are the official names of this protein?
Putative protein-lysine deacylase ABHD14B, Alpha/beta hydrolase domain-containing protein 14B, Abhydrolase domain-containing protein 14B.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. ABHD14 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: LUKL2_STAAW
Sequence: MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKEKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNPKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKEGQRLIVTYEVDWKNKTVKVVDKYSDNKSFREG
What are the official names of this protein?
Uncharacterized leukocidin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
Protein: Y1285_METTH
Sequence: MYILTISIPGYSGYSGDDMGDDEYLCSVEVAVNEIGGKWKSLVLCTLKDGKLRFSEINRRIPKITQRMLTRTLRELESSGLINREVYPEVPPRVEYCLTEKGKSVIPILDALCEWGKMYGSHQENSGEKAP
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator MTH_1285.
Protein: Y1078_BURO1
Sequence: MDIAHDLQSIGAQEQALVFPHFDPARAWALGNRMHALATSRGHAIAIDIVTFGQPLFYAALAGATPDNADWVRRKRNVVAHFRRSSYAIGLRMQQAGATLADKHGLPVAEYASHGGSFPLTVAGAGVIGSITASGLPQRADHEFVVEALCAELGHDYAVLALARS
What are the official names of this protein?
UPF0303 protein Bcen_1078.
What is the protein family that this protein belongs to?
Belongs to the UPF0303 family.
Protein: Y557_CAMJD
Sequence: MGRAFEYRRASKEARWDKMSKLFPKLAKAIQVAAKEGGIDPDMNPKLRSAIATAKANNMPKDNIDAAIKRASGKDSADIKNIHYEGKAAHGALVIVECMSDNPTRTVANVKAIFSKNGGEVLQNGSLGFMFTRKAVFHLEKFAGDLEELELDLIDAGFEELEQNEEELVISGDYTAFGELSSAIEAKGLVLKKAGLEYIPNNPVSFSKEQLSDIEKLLDKLEDDDDVQAVYTNID
What are the official names of this protein?
Probable transcriptional regulatory protein JJD26997_0557.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPEE2_PSEAE
Sequence: MPAEVAAGLPPLPPNHFYFYPPDPLLEGDGAITAIEDSDPFDQYVYRLRRVLYQGRTRWQNVLIADTYNYDRVLMLDGAIQSAESDESLYHELLVQPAMLAHDEPRDVLIIGGGEGATLREVLSHASVRRAVMVDLDRELVELCREHLFQWHQGAFDDPRCELLAEDGRAYLERDPSLYDVVIIDVVDMLDNGPAQALYTRQFYELLHSRLRPGGVVAVQGLEFSHSDDKPHAALARTLRSVFSQVHSYRATVPSFLSSWGFLLASDWLDTNHWQAEDIDRRIERKLGPLWLDHLDGDYLKACFVMDRETRFLLAQPGPVLEDGVPFVAPPDIEEIEFGPAQLPALART
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase 2, Putrescine aminopropyltransferase 2, PAPT 2, Spermidine synthase 2, SPDS 2, SPDSY 2.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_BIFLO
Sequence: MSRKGPSKKHVVLPDPIYGSTVVAQLINKILLDGKKSIAEDIVYSALDMVKEKSDQEPVAVLKRALDNIRPSLEVRSRRVGGATYQVPVEVKPNRANTLSLRWLTDFSRARREKTMAERLANEILDASNGLGASVKRREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: EUTC_ECOUT
Sequence: MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTNCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: CSN9_MOUSE
Sequence: MKPAVDEMFPEGAGPYVDLDEAGGSTGLLMDLAANEKAVHADFFNDFEDLFDDDDVQ
What is the function of this protein?
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes.  The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.  The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases.  CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.  Plays a role in cell proliferation.
What are the official names of this protein?
COP9 signalosome complex subunit 9.
What is the protein family that this protein belongs to?
Belongs to the CSN9 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleoplasm. Note=Excluded from the nucleolus. Recruited to the nucleoplasm and chromatin following DNA damage induction.
Protein: SSRP_FRASN
Sequence: MPKETGRKLIAQNKRARHDYDILDTYEAGLVLMGTEVKALRAGRASLVDGFAQIADGEIWLHNVHIPEYTEGTWTNHAPRRRRKLLLHRAEIEKLIGKTREGGLTVVPLSLYFKDGRAKVEIALARGRKNYDKRHALAERDAAREMSRIMGRQAKGRV
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: VTF3L_CAMPS
Sequence: MDNLFTFLHEIEDRYARTIFNFHLISCDEIGDIYGLMKERISSEDMFDNVVYNKDIHPAIKKLVYCDIQLTKHIINQNTYPVFNDSSQVKCCHYFDINSDNSNISSRTVEIFEREKSSLVSYIKTTNKKRKVNYGEIKKTVHGGTNANYFSGKKSDEYLSTTVRSNINQPWIKTISKRMRVDIINHSIVTRGKSSILQTIEIIFTNRTCVKIFKDSTMHIILSKDNDEKGCIHMIDKLFYVYYNLFLLFEDIIQNEYFKEVANVVNHVLTATALDEKLFLIKKMAEHDVYGVSNFKIGMFNLTFIKSLDHTVFPSLLDEDSKIKFFKGKKLNIVALRSLEDCINYVTKSENMIEMMKERSTILNSIDIETESVDRLKDLLLK
What is the function of this protein?
Acts with RNA polymerase to initiate transcription from intermediate gene promoters.
What are the official names of this protein?
Intermediate transcription factor 3 large subunit, VITF-3 45 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviruses A23 family.
Protein: YM11_PARTE
Sequence: MSTDFVFTPNFSTGFSCLKSDVVIHIAQWQYWWWFWFTYLWSLYFFFISRSIRARTFKMRPKIYTSFRSHGKWGDFLACIVPVIWCFNILVNSNFILRLMEWQNESTIFTSCIRARQWYWIYKFELKNILDLLTVPKKVGWNKWLIHTGNSIEVADDYFYALRIRAQNSWTSKYWKTFVRSLKKFKVSNNIHFIDDVVTAKKFKASVLSFMPYNQFDDKTLGFNLAKTNDSTVLLENDIFCDNFLFKGGDSWLCESIVFNHFGKKKIGGKKSDTLFNALNKTMFLNRKFFKNFLYDIDALVSNAFLEKKPKYVNLTTKRTDYGDFSRFTKKRVFEKRPILITKAFFPLNMEAFDNEILNVSFDATVT
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF11.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PTH_CHLAA
Sequence: MWLIVGLGNPGERYARTRHNIGFRSVDTLAERHGLTFRPQRANSQLAEGNIYGQRVVLAKPQTYMNLSGQAVVALCNWYKIDPARELLVIYDDLDLPFAKLRIRERGSAGTHNGMRSIVAQLGTTEFPRLRVGIGQPPGKMDAADYVLGRFTPDEEAALPDLLGRIADAVEVILREGLTTAMNRYNPL
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SGF11_DEBHA
Sequence: MTEKPVTYQSLDMLDNILRQQTLASVSRYRSLKSTLGENEKKSVFIDDIMSSSKDIYGQDKQKLKVSETSKYFQCENCGRSIAGGRFAQHMTKCLERRRK
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
What are the official names of this protein?
SAGA-associated factor 11.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1456_LISMO
Sequence: MECVPQILVDADACPVKAEIKQVAKEFQLEVTFVASFNHYSVNTNGENWIFVDTGKESADMRMMNLAKKGDIIVTQDIGLASILLAKGTFVFSNRGELYREEEMSLMLDIRYRHAKERQQGKYSKGPKAMSDQDRSLFKDRLTTFLQNK
What are the official names of this protein?
UPF0178 protein Lmo1456, P17.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: 3L220_DRYCN
Sequence: MKTLLLTLVVVTIVCLDLGNSFSCYKTPYVKSEPCAPGENLCYTKSWCDRFCSIRGKVIELGCAATCPPAEPKKDITCCSTDNCNTHP
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 20, LNTX-20, Long neurotoxin 193R.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1264_STACT
Sequence: MMIKQLPENDKPKEKLIAKGAAHLADSELLAILINTGRKGHSSIEVAQDLIKMARSLKELKLLSLNDIMKVKGIGLNKAIILKAAFELGERMYIPDLDTKVKITSPQDAADYFLSRMMHLTHEQFEVLFLNSKNVVIRHEVIFVGTLNSSIVHPREVFKAAIKWSSNAIIVVHNHPSGDVTPSKEDILTTKRLQECGRVLGIELLDHIIIGDAKYLSMVEGGYFDD
What are the official names of this protein?
UPF0758 protein Sca_1264.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: UL33_MUHVS
Sequence: MDVLLGRDETMDESDYLHVNNTCAPSLGLSIARDAETAINTVIILIGGPMNFVVLTTQLLSNRIYRSSAPTLYMTNLYFANLLTVTMLPFLILSNRGQISSSPEGCKLVAVTYYASCTAGFSTLALISVNRYRVIHQSTNKNAAGSKKKTYGVLALVWLTSLMCASPAPTYVTVLAHDGDTPDSVHETCIIFFNYDQVKTVLATFKILICIVWGVMPVVMMTWFYLFFYKRLKLTSYRRRSHTLAFVSTLILSFLVLQTPFVGIMIFDSYAVIEWDVTCESINSRDAVAMLARVVPNFHCMLNPVLYAFLGRDFNKRFMQCITGKLFSRRRMLQERAGVRSPSTPHRAARQLAKIGTLTRSCSRSELQRSASAPPPQ
What is the function of this protein?
Plays an important role in vivo, in particular in the dissemination to or replication in the salivary gland.
What are the official names of this protein?
G-protein coupled receptor homolog M33.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein.
Protein: RBFA_DEIRA
Sequence: MSVPFRALRCRDEVAVFFLAAPGPLMKPEQVQAQMSRVLSSAIAELRDPRVPLIVTVERVHVTPDYGQARVYVSAIGADMPELLDALTHARGRLQRELSAHVRMRRTPTLEFHAADDQRFPAAPGSTW
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_SHEPA
Sequence: MSEELTPQQVTRMTKLQKRLRTEVGRAIGDYNMIEEGDRVMCCLSGGKDSYAMLDILLNLQQRAPIKFEIVAVNLDQKQPGFPEDILPAYLDTLGVAYHILEKDTYSIVKDKIPEGKTTCSLCSRLRRGTLYGFAQKIGATKIALGHHRDDIIETMFLNMFFAGKMKAMPPKLLSDDGANMVIRPLAYAREKDIAEYAALKGFPIIPCNLCGSQENLKRAAVKEMLVQWDKQHPGRIETIFTAMQNTAPSQGVDREQFDFLSLQRDPDAPMSGQVAESDLPAFDFVDVSNNGHINLDAAARIDVVSTYTPE
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLM_ARATH
Sequence: MTKGGLGIAAMSYVVIDYMRYVSPVWHSRLMPVLWSVLAIAVVTRVLFYKHWSKELRAAIPFLGSIVFLLCALLFEALCVRSVTAVLGLDWHRETPPLPDTGQWFLLALNESLPGTLVEILRAHIIGLHHFLMLFIMLGFSVVFDSVKAPGLGLGARYIFTMGVGRLLRAITFVSTILPSARPWCASARFNNVPSQPHRWAQKYYVPYANDPAAIRKLLHWDAAYADPGSYIGDYRADWGSMSFLSEFLRPSYSEGSSWFALLKKAGGGCNDLMYSGHMLVAVLTAMAWTEAYGGFSSAMIWLFVAHSAQREIRERHHYTVDCIVAIYVGILLWKMTGFIWSAERKTKQTKLEKIQNSLIHAAKDGDIETVRRLVEEIEVSSRVEKQSKVISNRTMTVFACATVITTLTIVILALTLTSDG
What is the function of this protein?
Catalyzes the biosynthesis of sphingolipids with very long-chain fatty acid (VLCFA) (PubMed:31182845).  Required for the formation of plasmodesmal cytoplasmic sleeve during the transition from type I to type II plasmodesmata to modulate post-sieve elements (SE) unloading and symplastic cell-to-cell molecular trafficking at the phloem pole pericycle (PPP)-endodermis interface in roots (PubMed:31182845).
What are the official names of this protein?
Protein PHLOEM UNLOADING MODULATOR.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ZC3C1_PONAB
Sequence: MAAPCEGQAFAVGVEKNWGAVVRSPEGTPQKIRQLIDEGIAPEEGGVDAQDTSATSQSVNGSPQAEQPSLESTSKEAFFSRVETFSSLKWAGKPPELSPLVCAKYGWVTVECDMLKCSSCQAFLCASLQPAFDFDRYKQRCAELKKALCTAHEKFCFWPDSPSPDRFGMLPLEEPAILVSEFLDRFQSLCHLDLQLPSLRPEDLKTMCLTEDKISLLLHLLEDELDHRTDERKTTTKLGSDIQVHVTACILSVCGWACSSSLEPMQLSLITCSQCMRKVGLWGFQQIESSMTDLDASFGLTSSPIPGLEGRPERLPLVPESPRRMMTRSQDATFFPGSEQAEKSPGPIVSRTRSWDSSSPVDRPEPEAASPTTRTRPVTRSMGTGDPSGLEVPSSPLRKAKRARLCSSSSSDTSSRSFFDPTSQHRDWCPWVNVTLGKESRENGGTEPDASAPAEPGWKAVLTILLAHKQSSQPAETDSMSLSEKSRKVFRIFRQWESLCSC
What is the function of this protein?
Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1).  Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase.  Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry (By similarity).
What are the official names of this protein?
Zinc finger C3HC-type protein 1, Nuclear-interacting partner of ALK, Nuclear-interacting partner of anaplastic lymphoma kinase.
What are the subcellular locations of this protein?
Nucleus.
Protein: D212_DORVU
Sequence: MKLIKTFLFLFVVLLVLSEVSAEPRFGRLIRLIVKIARRAHRARSAVKAASNVAELAHGE
What is the function of this protein?
Peptide that induces pain in mammals and has insecticidal, antimicrobial and antiparasitic activities.  Induces irreversible paralysis in D. melanogaster when tested at high doses.  Shows a moderate antiparasitic activity against the major pathogenic nematode of ruminants (H. contortus, EC(50)=24. 5 uM).  Has moderate to potent antimicrobial activities against all Gram-positive and -negative bacteria tested, and against the fungus C. neoformans (var.  grubii), but has no activity against the fungus C. albicans.  Strongly induces the increase of intracellular calcium in mice DRG neurons, which is a proxy for neuronal activation that would occur during nociception.  This increase is due to influx of extracellular calcium, suggesting that the peptide forms pore or channel in neuronal cell membranes.  In addition, intraplantar injection in mice provokes nocifensive behavior, suggesting a pain-inducing activity.
What are the official names of this protein?
DELTA-limacoditoxin(2)-Dv12, DELTA-LCTX(2)-Dv12, Cecropin-like peptide, Vulnericin.
What is the protein family that this protein belongs to?
Belongs to the limacoditoxin-2 (cecropin-like) family.
What are the subcellular locations of this protein?
Secreted.
Protein: G6PI_STRP1
Sequence: MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDKDEFARILTAAEKIKADSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEANKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNVLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3348_STRCO
Sequence: MRLGVLDVGSNTVHLLVVDAHPGARPLPAHSHKVELRLAQLLDEDGAIGPDGVDQLAAVVREALQAAEDKGVEDLLPFATSAVREASNADDVLARVRAETGVELTVLTGAEEARLTFLAARRWFGWSAGRLLVLDIGGGSLEIAYGMDEEPDAAVSLPLGAGRLTAARLPDDPPHPDDVRALRRHVRTEIARTVGEFSRLGAPDHVVATSKTFRQLARITGAARSAEGLYVQRELKRASLEAWVPRLAAMTSTERAELPGVSEGRAHQLLAGALVAEGAMDLFRVESLEICPWALREGVILRRLDHMGQ
What are the official names of this protein?
Uncharacterized protein SCO3348.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
Protein: GLRX8_YEAST
Sequence: MSAFVTKAEEMIKSHPYFQLSASWCPDCVYANSIWNKLNVQDKVFVFDIGSLPRNEQEKWRIAFQKVVGSRNLPTIVVNGKFWGTESQLHRFEAKGTLEEELTKIGLLP
What is the function of this protein?
Glutathione-dependent oxidoreductase with lower activity compared to the other members of the glutaredoxin family.  The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase.
What are the official names of this protein?
Glutaredoxin-8, Glutathione-dependent oxidoreductase 8.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family.
Protein: TOLB_RICFE
Sequence: MRNIIYFILSLLFSFKGYALETINIEHGRADPTPIAVNKFNADSSADDVVGHDVVKVISNDLKLSGLFRPISSASFIEEKTGIEYKPLFAAWRQINASLLVNGEVKKLESGKLKISFILWDTLLEKQLAGEILEAPENLWRRAAHKIADKIYEKITGDAGYFDTKIVYVSESTSLPKIKRIALMDYDGANNKYLTNGKSLVLTPRFARSADKIFYVSYATKRRALVYEKDLKTGKESVVGDFSGISFAPRFSPDGRKAVMSIAKNGSTHIYEIDLATKRLHKLTDGFGINTSPSYSPDGKKIVYNSDRNGVPQLYIMNSDGSDVQRISFGGGSYTAPSWSPRGDYIAFTKITRGAEGKTFNIGIMKACPQDDENSERIITSGYLVESPCWSPNGRVIMFAKGWPSRAKAPGKNKIFAIDLTGHNEREIITPADASDPEWSGVLN
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: DRC6_HUMAN
Sequence: MTPELMIKACSFYTGHLVKTHFCTWRDIARTNENVVLAEKMNRAVTCYNFRLQKSVFHHWHSYMEDQKEKLKNILLRIQQIIYCHKLTIILTKWRNTARHKSKKKEDELILKHELQLKKWKNRLILKRAAAEESNFPERSSSEVFLVDETLKCDISLLPERAILQIFFYLSLKDVIICGQVNHAWMLMTQLNSLWNAIDFSSVKNVIPDKYIVSTLQRWRLNVLRLNFRGCLLRPKTFRSVSHCRNLQELNVSDCPTFTDESMRHISEGCPGVLCLNLSNTTITNRTMRLLPRHFHNLQNLSLAYCRRFTDKGLQYLNLGNGCHKLIYLDLSGCTQISVQGFRYIANSCTGIMHLTINDMPTLTDNCVKALVEKCSRITSLVFTGAPHISDCTFRALSACKLRKIRFEGNKRVTDASFKFIDKNYPNLSHIYMADCKGITDSSLRSLSPLKQLTVLNLANCVRIGDMGLKQFLDGPASMRIRELNLSNCVRLSDASVMKLSERCPNLNYLSLRNCEHLTAQGIGYIVNIFSLVSIDLSGTDISNEGLNVLSRHKKLKELSVSECYRITDDGIQAFCKSSLILEHLDVSYCSQLSDMIIKALAIYCINLTSLSIAGCPKITDSAMEMLSAKCHYLHILDISGCVLLTDQILEDLQIGCKQLRILKMQYCTNISKKAAQRMSSKVQQQEYNTNDPPRWFGYDREGNPVTELDNITSSKGALELTVKKSTYSSEDQAA
What is the function of this protein?
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.  Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
Dynein regulatory complex subunit 6, F-box and leucine-rich repeat protein 13, F-box/LRR-repeat protein 13.
What is the protein family that this protein belongs to?
Belongs to the DRC6 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: GCSPA_STAA3
Sequence: MSHRYIPLTEKDKQEMLQTIGAKSIGELFGDVPSDILLNRDLNIAEGEAETTLLRRLNRIASKNITKETHTSFLGAGVYDHYAPSVVDAMISRSEFYTAYTPYQPEISQGELQAIFEFQTLICELTDMDVANSSMYDGMTSFAEACILAFSQTKKNKIVVSKGLHYQALQVLHTYAKTRKEFEVVEIDLDGTVTDLKKLEAAVDDETAAVAVQYPNFYGSIEDLEKIHSFIEDKKALFIVYANPLALGLLTPPGSFGADIVVGDTQPFGIPAQFGGPHCGYFATTKKLMRKVPGRLVGQTQDDEGNRGFVLTLQAREQHIRRDKATSNICSNQALNALASSIAMSALGKQGIYDIAVQNIEHANYAKQQFIKKGFEVLDGTSFNEFVVKFDKPIQQVNEELVKYNIIGGFDLGVVSDDFKNHMLIAVTELRTKDEIDTFVEKAGELND
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.