PharMolix/UniProtQA huggingface dataset:
Protein: SEN34_SCHPO
Sequence: MEDEKFPISYVHGKFLVFDVQAVEVFRKNYHILGTLVGTLPQLPQQNVFLGLPMELSKEEAFYLIEKGISYIVDDTKVHKQLLENTTKDDVKQCLKKRQSLAYDQMIAAKKKENEKKIEIMKKLGRTLPLDPLNYDEHDSFDLSWIPVDTVTTRIAEKSSMNDDFHKEEDVFENLDINRYLMFKSLVDTGFYLNPGLRFGCQFVAYPGDALRYHSHYLVNSYKWDQEIPVLFLIGGGRLGTAVKKTWLIGGSNDRNINMNGEKSKEELLLLPVRHFSIEWAGFG
What is the function of this protein?
Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA.  It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini.  There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.  It probably carries the active site for 3'-splice site cleavage (By similarity).
What are the official names of this protein?
Probable tRNA-splicing endonuclease subunit sen34, tRNA-intron endonuclease sen34.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family.
Protein: APAG_SHIB3
Sequence: MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
What are the official names of this protein?
Protein ApaG.
Protein: SYN_CLOAB
Sequence: MENVLVKQLYRLSSEFGGKKVRLSGWVRTIRASKSFGFIEINDGSFFKNIQVVFDDKLDNFKEISKFIISSTITVEGEFVLTPNAKQPFEIHAENITLEGNSDNDYPLQKKRHTLEYLRSIAHLRPRSNTFSAVFRVRSLAAYAVHKFFQERDFVYVNTPLITASDAEGAGEMFQVTTLDLKNPPKNEEGNIDFSKDFFGKKANLTVSGQLSAETFALAFRNVYTFGPTFRAEESNTTRHAAEFWMIEPEMAFAELSDYLDTAEEMVKYIINFVMENAPEEMEFFNTRIDKGLFDRLHNVVNSEFGRITYTEAVDILEKSGEKFEYPVKWGIDLQTEHERYLTDKVFKKPLFVTDYPKDIKAFYMRINDDNKTVAAADLLVPGVGEIIGGSQREERLAVLEKRMEELNLNKEDYWWYLELRKYGETKHSGYGLGFERMIMYLTGISNIRDVIPFPRTTGSAEF
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_INCAA
Sequence: MEINPYLMFLNNDVTSLISTTYPYTGPPPMSHGSSTKYTLETIKRTYDYSRTSVEKTSKVFNIPRRKFCNCLEDKDELVKPTGNVDISSLLGLAEMMEKRMGEGFFKHCVMEAETEILKMHFSRLTEGRQTYDWTSERNMPAATALQLTVDAIKETEGPFKGTTMLEYCNKMIEMLDWKEVKFRKVKTMVRREKDKRSGKEIKTKVPVMGIDSIKHDEFLIRALTINTMAKDGERGKLQRRAIATPGMIVRPFSKIVETVAQKICEKLKESGLPVGGNEKKAKLKTTVTSLNARMNSDQFAVNITGDNSKWNECQQPEAYLALLAYITKDSSDLMKDLCSVAPVLFCNKFVKLGQGIRLSNKRKTKEVIIKAEKMGKYKNLMREEYKNLFEPLEKYIQKDVCFLPGGMLMGMFNMLSTVLGVSTLCYMDEELKAKGCFWTGLQSSDDFVLFAVASNWSNIHWTIRRFNAVCKLIGINMSLEKSYGSLPELFEFTSMFFDGEFVSNLAMELPAFTTAGVNEGVDFTAAMSIIKTNMINNSLSPSTALMALRICLQEFRATYRVHPWDSRVKGGRMKIINEFIKTIENKDGLLIADGGKLMNNISTLHIPEEVLKFEKMDEQYRNRVFNPKNPFTNFDKTIDIFRAHGPIRVEENEAVVSTHSFRTRANRTLLNTDMRAMMAEEKRYQMVCDMFKSVFESADINPPIGAMSIGEAIEEKLLERAKMKRDIGAIEDSEYEEIKDIIRDAKKARIESR
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: ARLY_RUTMC
Sequence: MTNDTQYKRHKTVLKEESRRTIQINKSWGGRFNEPTDEFVKIFGASIFFDKILAPYDIQGSIAHATMLQEVGLLTENEKNKIIKGLERILSEVKTGEFKWSITLEDIHMNIEARLVKMIGDTGKKLHTGRSRNDQIVTDIRLYLRDQVDDITNEIKRLQLVLADLAEKETNTIMPGFTHLQAAQPISFGHHMMAYFEMLARDVERLFDCRKRINSMPLGSAALAGTTYSIKRTRTAELLGFERICLNSLDGVSDRDFVIEFLSTASIIMMHLSRFSEELILWSSAQFNFIELPDSFCTGSSIMPQKKNPDVPELVRGKTGRVYGNLTSLLTIMKSQPLAYNKDNQEDKEPLFDTVDTLKACLRVFADMIPTIQIKRDNMYNSTKQGYTTATDLADYLVNKGLPFRDAHKVVGKSVAYGIEHQKDLSELSLEELQAFDSRIENDVFEILSLEGSLNARNHLGATSPNQVKQAIKIARKTLK
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRNL1_MOUSE
Sequence: MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYINFELRYKEVERARTIYERFVLVHPAVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQEAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEADTVREVYERAIANVPPIQEKRHWKRYIYLWVNYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWLYYAQFEIRQKNLPFARRALGTSIGKCPKNKLFKGYIELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGDIERARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRQLLQRTQHVKVWISFAQFELSSGKEGSVAKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEDEFGTVSDKERVDKLMPEKVKKRRKVQADDGSDAGWEEYYDYIFPEDAANQPNLKLLAMAKLWKKQQQEREAAEQDPDKDIDESESSSF
What is the function of this protein?
Involved in pre-mRNA splicing process.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.
What are the official names of this protein?
Crooked neck-like protein 1, Crooked neck homolog.
What is the protein family that this protein belongs to?
Belongs to the crooked-neck family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Note=Colocalizes with core spliceosomal snRNP proteins.
Protein: MURA2_LISIN
Sequence: MTNKLIIQGGKKLAGTLQVDGAKNSAVALIPAAILAESEVVLEGLPDISDVYTLYDILEELGGSVRYDNKTAVIDPADMISMPLPTGNVKKLRASYYLMGAMLGRFKKAVIGLPGGCYLGPRPIDQHIKGFEALGAKVTNEQGAIYLRADELKGARIYLDVVSVGATINIMLAAVRAKGKTIIENAAKEPEIIDVATLLSNMGAIIKGAGTDTIRITGVEHLHGCHHTIIPDRIEAGTFMVLAAASGKGVRIENVIPTHLEGIIAKMTEMGIPMDIEEDAIFVGEVEKIKKVDIKTYAYPGFPTDLQQPLTALLTRAEGSSVVTDTIYPSRFKHIAEIERMGGKFKLEGRSAVVSGPVKLQGSKVTATDLRAGAALVIAGLLAEGTTEIHGVEHIERGYSKIIEKLSAIGADITRSTAAETKL
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AP2L3_ARATH
Sequence: MAKVSGRSKKTIVDDEISDKTASASESASIALTSKRKRKSPPRNAPLQRSSPYRGVTRHRWTGRYEAHLWDKNSWNDTQTKKGRQVYLGAYDEEEAAARAYDLAALKYWGRDTLLNFPLPSYDEDVKEMEGQSKEEYIGSLRRKSSGFSRGVSKYRGVARHHHNGRWEARIGRVFATQEEAAIAYDIAAIEYRGLNAVTNFDVSRYLNPNAAADKADSDSKPIRSPSREPESSDDNKSPKSEEVIEPSTSPEVIPTRRSFPDDIQTYFGCQDSGKLATEEDVIFDCFNSYINPGFYNEFDYGP
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
AP2-like ethylene-responsive transcription factor At1g79700.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. AP2 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: ANKF1_HUMAN
Sequence: MNEKRLLFKDRHFTCSKIIGRRFACFAQRLSHRRKQSQCDLLNESTGQLPTTCSSAASNSINWNCRVKMTQQMQNLHLCQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRALHQHYSCRESTKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIAVIFYYKDNILVTNEDQVPIVEIDDSHTSSITQDFLWFTKLSCMWEDIRWLRQSIPISSSSSTVLQTRQKMLAATAQLQNLLGTHNLGRVYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLFPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENNNISREEWEWIQKLSGSESMESVDHTSDCPMQLFFYELQMAVKALLQQINIPLHQARNFRLYTQEVLEMGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDPSDEQSLKKINSTSSSHIDCLPSPPPSPEMHRRKTVSDSQPCSDEEACSEVFLPTNSDYDSSDALSPRDLDLVYLSSHDIAQQTLSGLSGSAPDVLQVHDVKTPLGPGQDPQGEGPNPDHSCAEFLHSLTLTGFTPKNHAKTVSGGRPPLGFLGKRKPGKHPHYGGFSRHHRWLRIHSETQSLSLSEGIYTQHLSQACGLAQEPKEAKRAGPALDDPRGLTLAHAASLPEERNSSLQDARPSVRRLYVEPYAAAVVAQDEKPWASLSPPSGGRITLPSPTGPDVSQEGPTASPMSEILSSML
What is the function of this protein?
May play a role in neuronal function.
What are the official names of this protein?
Ankyrin repeat and fibronectin type-III domain-containing protein 1.
Protein: DNLJ_SALA4
Sequence: MEPIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRELEAQRPDLITPDSPTQRVGAAPLTAFNQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKSTENVIWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLHGDNIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGILEGGELPDTHLGRLLQFKAWGLPVSDRVTLCDSPQAVLDFYRNVEKDRPTLGFDIDGVVIKVNSLALQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETRPIVFPTHCPVCGSDVERVEGEAVTRCTGGLICGAQRKESLKHFVSRRAMDVDGMGDKIIDQLVEREYVHTPADLFRLTAGKLTGLDRMGPKSAQNVVNALEKAKATTFARFLYALGIREVGEATAAGLAAYFGTLEALQAATIDELQKVPDVGIVVATHVFNFFAEESNRDVIGQLLAEGVHWPAPVVINVQEIDSPFAGKTVVLTGSLSQMSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGITVIDEAEMIRLLDA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: DEFI8_XENTR
Sequence: MEYDDKLVRFRQGHLNPFDKQGEAERQPAACETEPSKDFPTSSPLSVPEFHCPDRVMDLGVSEDHFSRPVGLFLASDIQQLRQAIEECKQEILELPEHSDRQKDAVVRLIHLRLKLQELNDPLEDEPNLRILLEHRFYKEKSKSVKHLCDKCSTFIWGLIQTWYTCTGCSYRCHSKCLNLITKPCVRSKVSHQAEYELSICPEAGLDSQDYRCAECRTPISLRSVPSEARQCDYTGQYYCISCHWNDIAVIPARAIHNWDFEPHKVSRCSMRYLALMLGRPVLKLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQDRQHFVENDDMYSLQDLLDISSGRLGCSLTEIHTTFAKHIKLDCERCQAKGFVCELCKEGDILFPFDSHTSVCQDCAAVFHRDCYYDNSTSCPRCTRLNLRKQVQNPGEEP
What is the function of this protein?
Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts.  Involved in bone resorption.
What are the official names of this protein?
Differentially expressed in FDCP 8 homolog, DEF-8.
What is the protein family that this protein belongs to?
Belongs to the DEF8 family.
Protein: CYB_KRYMA
Sequence: MTSIRKSHLTLKALNESMIDLPAPKNISAWWNFGSLLSLCLALQILTGLFLAMHYTSDISTAFSSVVHICRDVNYGWLIRSIHANGASFFFICIYLHIGRGLYYGSYLNKEAWSAGVILLLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAIPYVGENIVQWLWGGFSVDSATLTRFFAFHFLFPFGIIAMTLVHLLFLHEKGSSNPVGINSNADKIYFHPYFIYKDLIGFAWFALFLITLVLFIPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAILRSIPNKLGGVFALLASILILLIVPILHTSKWQNFAFRPLAQIFMGLLVVDVAILTWIGGMPVEPPFIIIGQIASFLYFFLFLVFFPLSGWLENKMLESCTKSSALRALVL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: IHFA_YERPB
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEVRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVESATPKE
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ANMK_PRB01
Sequence: MSKKIYIGAMTGTSHDAIDISFLSIGTKIHLEYFHSIKFPKSLRLKVKKLIENNESSLSDLGTINKEIGFLFSKSINEAIGFSKIKKSSIECVAISGQTIRHEINKRFPFSMQIGDPNIVAKETGLLVVSDFRNMHIALGGEGAPLVPEFHNQLFYKARNPRIILNIGGISNYSFVKNRNDIWGTDVGPGNAILDAYCSDFLQIPFDKNGAIAAKGKVDHIELGRLLQNNFFKRKCPKSTGKELFNIKILSKKFLKKKAEDILCTLVEFSAKSIINSIHKNGHNNCDIVICGGGAHNKYLVKRISEMASNDIVLSSDLGHDVFAIESMAFAWMGYKRVSNEALIVQTSSKNVKGLLGSITKSKL
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: CP17A_PERLE
Sequence: MWELVCLLLLILAYLFWPKPKTSDAKFPRSLPFLPLVGSLPFLPRHGHMHVNFFKLQEKYGPIYSLRLGTIPTVIIGQYQLAREVLIKKGKEFSGRPQMVTLGLLSNQGKGIAFADSDDAWQLHRKLALSSFALFRDGDQRLETIICQEASSLCDLLLTHNEESVDLSQPIFMSVTNIICAICFSTSYENRDPILTTIQTFTEGILNCLDNENLVDIFPWLTIFPNKTLEKIKRHVKVRDEVLIDMLEKCKEKFNNDSISNLTDILIQAKMNADNNNTTDHQGSFSDSHILSTVGDFFGAGIETTTSVLCWIVAFLLHNPEVKKKIQKEIDQNIGFSRTPTFNDRNHLLMLEATIREVLRIRPVAPMLIPHKANIDSSIGEFTIPKDTHVVINLWALHHNEKEWDQPDRFMPERFLDATGSHLITPSLSYLPFGAGPRACIGEVLARQVLFLYVACLLQRFDLDVPDGAPMPCLKGDPKVVFLIDPFKVKVTVRQAWKDAQAEVGTWRP
What is the function of this protein?
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis.  Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways.  A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage.  The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol.  Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione.  Has 16-alpha hydroxylase activity.  Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA.  Also 16-alpha hydroxylates androgens, relevant for estriol synthesis.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
What are the official names of this protein?
Steroid 17-alpha-hydroxylase/17,20 lyase, 17-alpha-hydroxyprogesterone aldolase, CYPXVII, Cytochrome P450 17A1, Cytochrome P450-C17, Cytochrome P450c17, Steroid 17-alpha-monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Microsome membrane.
Protein: L2GL2_PONAB
Sequence: MRRFLRPGHDPVRERLKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAIGTRSGAIKLYGAPGVEFMGLHRENNAVTQIHLLPGQCQLVTLLDDNSLHLWSLKVKGGASELQEDESFTLRGPPGAAPSATQITVVLPHSSCELLYLGTESGNVFVVQLPAFRALEDRTISSDAVLQRLPEEARHRRVFEMVEALQEHPRDPNQILIGYSRGLVVIWDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCHSDGSYCQWPMSSEAQQPEPLRSLVPYGPFPCKAITKILWLTTRQGLPFTIFQGGMPRASYGDRHCTSVIHDGQQTAFDFTSRVIDFTVLTEADPAAAFDDPYALVVLAEEELVVIDLQTAGWPPVQLPYLASLHCSAITCSHHVSNIPLKLWERIIAAGSRQNAHFSTMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRFWDASGVCLRLLYKLSTVRVFLTDTDPNENLSAHGEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKYSGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADLLQDQEGYRWKGHERLAAHSGPVRFEPGFQPFVLVQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFDHQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKSLRQSFRRMRRSRVSSRKRRPAGPPGEVQEGSVKAERPGLQNMELAPVQRKIEARSVEDSFTGFVRTLYFADTYLRDSSRHCPSLWAGTNGGTIYAFSLRVPPAERRMDETVRAEQAKEIQLMHRAPVVGILVLDGHSVPLPEPLEVAHDLSKSPDMPGSHQLLVVSEEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVAHFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLKPQVRYSCIRREDVSGIASCVFTKYGQGFYLISPSEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGAGPKKAPSRVRNSGTQSDGEEKQPGLVMERALLSDERVLKEIQSTLEGDRGSRNWRSHRAAVGCSLGNGGE
What is the function of this protein?
Part of a complex with GPSM2/LGN, PRKCI/aPKC and PARD6B/Par-6, which may ensure the correct organization and orientation of bipolar spindles for normal cell division.  This complex plays roles in the initial phase of the establishment of epithelial cell polarity (By similarity).
What are the official names of this protein?
LLGL scribble cell polarity complex component 2, Lethal(2) giant larvae protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat L(2)GL family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localized in the perinuclear structure and faintly at the cell-cell contacts sites in the interphase. Localized at the cell periphery during metaphase. Cortical localization in mitotic cells (By similarity).
Protein: BDS21_BUNCN
Sequence: GVSCKCGSKKGVYWFGQITGCPGGHGYKGSCSYVLG
What are the official names of this protein?
Toxin Bcg III 29.21, Toxin Bcg 29.21.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 3 (BDS) potassium channel toxin family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: DEF_CLOTE
Sequence: MAIRNLRFLGDELLRKKSRRVEKIDDRIQALLDDMLDTMYENNGVGLAAPQVGILKRVVVIDIGEGPLFLINPEIIEQEGSYIEQEGCLSVPGRQGEVERPYRVKVKAQNRDGKEIIVEGEEFLAKALCHEIDHLNGVLFVDKIIDVKGE
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: SPER_STRPU
Sequence: MGLPMMLQQYCWAACLVICIAISSVDDVGAEQNYGREAVEGNIRLIHGRTENEGSVEIYHATRWGGVCDWWWHMENANVTCKQLGFPGARQFYRRAYFGAHVTTFWVYKMNCLGNETRLEDCYHRPYGRPWLCNAQWAAGVECLPKDEPQGSLRMILGDVPNEGTLETFWDGAWGSVCHTDFGTPDGNVACRQMGYSRGVKSIKTDGHFGFSTGPIILDAVDCEGTEAHITECNMPVTPYQHACPYTHNWDVGVVCKPNVEGDIRLMDGSGPHEGRVEIWHDDAWGTICDDGWDWADANVVCRQAGYRGAVKASGFKGEDFGFTWAPIHTSFVMCTGVEDRLIDCILRDGWTHSCYHVEDASVVCATDDDDTIEIEPKHTRVRIVGMGQGQGRVEVSLGNGWGRVCDPDWSDHEAKTVCYHAGYKWGASRAAGSAEVSAPFDLEAPFIIDGITCSGVENETLSQCQMKVSADMTCATGDVGVVCEGSTAPPSGMSIAVIGGAAGGGVAGLAVAAFAFYYIKFVKPAGGGGQA
What is the function of this protein?
Receptor for the egg peptide speract.
What are the official names of this protein?
Egg peptide speract receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PLSX_MANSM
Sequence: MSRLTLALDVMGGDIGPRITIPASIKALEKDPMLSLLLFGDSQQINPLLEQVPSALKERLRVCHCSRVVENNQGLSYALRHSKGTSMRLAIEAVQKGEAQGCVSAGNTAALMGLSKVLLQPLKGIDRPALISLLPTMDGGRTVMLDLGANIDCNANNLYQFALMGAIFAENQLDLVFPRIALLNIGIEEIKGYKSIREAADLLTGNSSLNYIGFIEGNLLLNGKADVIVSDGFVGNIALKTLEGAAKNVISLIKGKSRNHLLKPLFNWLIKLLFKDSYQRLQKINPDQYNGASLIGLTSIVVKSHGAANIEAFNNAIHDAALQARQQIPEKILAGLQK
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: TATB_CORGB
Sequence: MFSSVGWGEIFLLVVVGLVVIGPERLPRLIQDARAALLAARTAIDNAKQSLDSDFGSEFDEIRKPLTQVAQYSRMSPKTAITKALFDNDSSFLDDFDPKKIMAEGTEGEAQRNKQAADNNANVVERPADGSTARPTQNDPKDGPNYSGGVSWTDII
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: HLY3_VIBPH
Sequence: MKYRYFAKKSFLFISMLAAFKTFAFELPSVPFPAPGSDEILFVVRDATFNTNAPVNVKVSDFWTNRNVKRKPYKDVYGQSVFTTSGTKWLTSYMTVNINDKDYTMAAVSGYKRGHSAVFVKSDQVQLQHSYNSVANFVGEDEDSIPSKMYLDETPEYFVNVEAYESGSGNILVMCISNKESFFECEHQK
What is the function of this protein?
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined.
What are the official names of this protein?
Thermostable direct hemolysin-related.
What is the protein family that this protein belongs to?
Belongs to the TDH hemolysin family.
Protein: RL31_BUCBP
Sequence: MKKKIHPDYFKINVTCSCGNNINIFSTLSKNINVDVCSKCHPFYTGQQRTSDTGGRIEKFHKRFNISSH
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: VATE_HALSA
Sequence: MSLETVVEDIRDEARERAKEIRADADERADEIVAEAEADADDIIADAEAEVTAEIDQEREQQLSSAELEAKQMRLEARRDALQSVRSAVEDRIVALDGDEREELTRELLDAASTEFDGADTVRVFGRADDEALISEILDDYDGYEYAGEYDCLGGVVVESDASRIRVNNTFDSILADAWENNLKAISARLFDEEQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: TFPI2_MOUSE
Sequence: MDPAMPLQLWNLPLLLVGSVLGLTSVSAQGNNLEICLLPLDAGPCQALIPKFYYDRDQQKCRRFNYGGCLGNANNFHSRDLCQQTCGSIEKVPPVCRSELKTYPCDKPNIRFFFNLNTMTCEPLRPGLCSRTINVFSEEATCKGLCEPRKHIPSFCSSPKDEGLCSANVTRFYFNSRNKTCETFTYTGCGGNENNFYYLDACHRACVKGWKKPKRWKIGDFLPRFWKHLS
What is the function of this protein?
May play a role in the regulation of plasmin-mediated matrix remodeling.  Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa.  Has no effect on thrombin (By similarity).
What are the official names of this protein?
Tissue factor pathway inhibitor 2, TFPI-2.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4826_BACC7
Sequence: MKMTSKKMKDELMKRLSRPEWDFQYDSEKEVLRIEQKDSKKGINVSLPGVVAKWEVNKEKAIEEVAYYVQEALIAMHKEENSAAKILPVIRSTSFPKQAEEGNPFIMTDHTAETRIYYALDSNKTYRLIDERLLQKLGLTEQQVREMALFNARSLSYEFKQDTVAGNTFYFLNTNDGYDATRILNESLLQSMREKISGDMVVAVPHQDVLIIADIVNEIGYDIIAQMTMKFFAEGHVPITSLSFVYEDGDFEPIFILAKNRKKTDGKEKG
What are the official names of this protein?
UPF0354 protein BCAH187_A4826.
What is the protein family that this protein belongs to?
Belongs to the UPF0354 family.