PharMolix/UniProtQA huggingface dataset:
Protein: RBSD_BACC1
Sequence: MKKHGVLNSEIASILASLGHTDTIVIADCGLPIPDGVKRIDLAVEIGKPSFLDVLQVVADDMAIEKVTLAEEVINNNAEINKEIELKLVEPALEYVSHEQFKEHTKKAKAIIRTGEATPYANVILHAGVIF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_RICRO
Sequence: MGITVLKNEGLDFHARISTPLSEIDDDIQKELLDLTKKVKIPGFRAGKVPVSIVKKKYGTSVRNDIIERRINHSVNHIIKEHNLNIIGRPKIEELQNESDKALEFTVKIELLPKITIPDLKKISLDRPKLEVNSKDVEEQLEKLAALTKNYTKESKAKIKDGDQVTIDAIGYIKEKTFEDGKLNDFKVIIGSNALIPGFEKQLIGSKTGSKVDVNVTFPENYHAKDLAGKDARFVVQIKAVHTAEPTVIDDEFAKKFQSNSLEELRTHFTKQIENESEEAINTIMKMNLFDKLEKLLDFDVPESLLEQEKNILKSGTDKNEQDESLLKDKSSKEITAYYNKLALRRVRIGLLLAEYAKSKNLQLEPDDLRKVIMQQARNFPGQENMIFDFYKNNPRAIEGLKGPALEDKAVQYIFNHEIKLKEKKYTKEELEKYLEAEEQRITLI
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: EBP2_CAEEL
Sequence: MVRKMNKLAKRLASTSKSRQPEPESDSDGSEFDFDNAIEEKPMEAMDIEEVESDGDDDERELQAAFAAGLLKDGLNIQVAKKRPIINKSAEMKEKLAEITKDLPWVETLEVVTPHSEMDKKVENDDFQRELNFYKQAEKAVQIAYPRLLNLGIKVLRPTDYYAEMAKSDTHMQKVRKRLLGIQEMKERQEAFRRIREEKKFAVKVQKEVLAAKNTEKKNLAEAVKKHKKGMKQQLEDMLNNVKRHGLDQDDDAPTGAFGDRLGGRGGAGRGGAGRGGSMRNAGELKRKLKSDKFGYGGKKKGMKRNNKESFNDLFGAPRGGFGGRGRGGGRGGRGGRGRR
What is the function of this protein?
Required for the processing of the 27S pre-rRNA.
What are the official names of this protein?
Probable rRNA-processing protein EBP2 homolog.
What is the protein family that this protein belongs to?
Belongs to the EBP2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: DUS3_PHANO
Sequence: MAGEGDQVASDAPVPSAVADSNGVESGNRPSSSNPEPSSDKKRVRTGSQDIDMADAPVKRQKGVAPIKAECVALPNIFIIHRSDNKAEVKTAPIDDDAAEAADARHKAGDSRDNRAGAKGKNNKKDKKQKGQNTSRTFGSSHDKLPLCGTRALSNEFSAPECRFGDKCKFEHDLRKYLKEGRREDLTTFDGQCPIYEVRGYCHLGWKCRFVGSHSEERATEHGRQELVLREDAERKAKFAGLEDDEVEVVNILPKEVRFGLSRRKIGTPRSDQYLEWINSNKDQERELFDNNQGDTEALKEERDARRAEYVEAPFRPSEKRRLYYGPETPVLAPLTTQGNMPYRRLCVDLGCQVTWSEMAMGMPLIQGERGEWALMKAHESEIAAPRFQSKGTVVQGYDNAADIRFGAQIAANKPWLANKTVEVLTDNCPKLRAIDLNCGCPINLVCEKGSGSALLDSEAKLENILRGMNYVSKEVPITVKVRMGTKDNHPTAQKLIKRLVLGGYEALASDKGTSGVAAITLHGRSKQQRYSKSADWSYIAECASLINRLKKEKDAQTDTAAEADPRDQANGGHVYFVGNGDCYSHEDYYNHMNNANVDSVMIGRGALIKPWIFEEIEKGQYLDKSATERLAYIEKFAKYGLQTWGSDELGIGTTRRFLLEWLSFAHRYVPVGLLEHLPPNIQDRPPRFRGRNDLETLMASEHYLDWIKLSEMFLGKAPPTFKFEPKHKSNAYEIEAEG
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ERAP1_MOUSE
Sequence: MPSLLPLVLTFLSVSSPSWCQNSDIESLKASNGDSFPWNNMRLPEYMTPIHYDLMIHANLSTLTFWGKTEVEIIASRPTSTIIMHSHHLQISKATLRRGAGEMLSEEPLKVLEYPAHEQVALLAAQPLLAGSLYTVIIDYAANLSESFHGFYKSTYRTQEGEMRILAATQFEPTAARMAFPCFDEPALKASFSIKIKRDPRHLAISNMPLVKSVNVAEGLIEDHFDITVKMSTYLVAFIISDFKSVSKMTKSGVKVSVYAVPDKINQADYALDAAVTLLEFYEDYFNIPYPLPKQDLAAIPDFQSGAMENWGLTTYRESSLLYDKEKSSASSKLGITMIVSHELAHQWFGNLVTMEWWNDLWLNEGFAKFMEFVSVTVTHPELKVEDYFFGKCFNAMEVDALNSSHPVSTPVENPAQIREMFDDVSYEKGACILNMLRDYLSADTFKRGIVQYLQKYSYKNTKNEDLWNSMMHICPTDGTQTMDGFCSRSQHSSSTSHWRQEVVDVKTMMNTWTLQKGFPLITITVSGRNVHMKQEHYMKGSERFPETGYLWHVPLTFITSKSDSVQRFLLKTKTDVLILPEAVQWIKFNVGMNGYYIVHYADDGWASLSGLLKEAHTTISSNDRASLINNAFQLVSIEKLSIEKALDLTLYLKNETEIMPIFQALNELIPMYKLMEKRDMIEVETQFKDFLLKLLKDLIDKQTWTDEGSVSERMLRSQLLLLACVRNYQPCVQRAERYFREWKSSNGNMSIPIDVTLAVFAVGAQNTEGWDFLYSKYQSSLSSTEKSQIEFSLCTSKDPEKLQWLLDQSFKGEIIKTQEFPHILTLIGRNPVGYPLAWKFLRENWNKLVQKFELGSSSIAHMVMGTTDQFSTRARLEEVKGFFSSLKENGSQLRCVQQTIETIEENIRWMDKNFDKIRLWLQKEKPELL
What is the function of this protein?
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides.  Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules.  Strongly prefers substrates 9-16 residues long.  Rapidly degrades 13-mer to a 9-mer and then stops.  Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus.  May play a role in the inactivation of peptide hormones.  May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney (By similarity).
What are the official names of this protein?
Endoplasmic reticulum aminopeptidase 1, ARTS-1, Adipocyte-derived leucine aminopeptidase, A-LAP, Aminopeptidase PILS, Puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP, VEGF-induced aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: KPRS_DEIRA
Sequence: MNSRRSPLLVFSGQSNRPLAQAICDNLGVPLGRSRTEKFTNDNLIVHYEESLREGDVFIVQTFSTPVSDAIMELMLMIDAAKSASAGRVTAVIPYYSYARSDKKDSPRISIAGRLVADLLQEAGADRVLTMTLHSPQVHGFFKVPVDHLSADVVLSQHFKKCVPDAHNGVVLAPDAGSIKRASQIARRLDSGLAMIDKERLSDTEVRPRALIGDVDGKTVFIVDDEISTAGSLVETVSIARSMGAKDVYVAVTHGVYSGPAIERIAALDVTQVASCNTVLVPQDKLDRAGGKLAVLDVAPLFASAIANIHTGASVSTLFT
What is the function of this protein?
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
What are the official names of this protein?
Ribose-phosphate pyrophosphokinase, RPPK, 5-phospho-D-ribosyl alpha-1-diphosphate synthase, Phosphoribosyl diphosphate synthase, Phosphoribosyl pyrophosphate synthase, P-Rib-PP synthase, PRPP synthase, PRPPase.
What is the protein family that this protein belongs to?
Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_YARLI
Sequence: MSLEAIRYDEKNHTLTILDQLRLPHESEYVPINNSDDGWKAIKDMVVRGAPAIAIVAILSLAVELVHGGKVSRDQTRAEVGSFISDRLDYLNTSRPTAVNLSDAVGSFKKLVQTQTGSASELIEAFLSASHKMLLDDVQDNKNIGKYGLEWIQKNVPQAANGHKISALTICNTGSLATAGYGTALGIIRALHEAGVLERVYALETRPYNQGSRLTAYELVHDGIPATLVTDSMAAALLRKNKDIGVIIVGADRVVLNGDTANKIGTFQLSILANHFDRKFIVAAPTTSIDVQTKSGEDIEIEERPAIELTQVKGVDANKQPLTVSVAAPGIEVWNPAFDYAPYKLIDAIVTEKGVAEKTGGEFNLKEFKSAN
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PFA5_ASHGO
Sequence: MWQCKNKSRWWYSLVPILCICIMCYGAIAYSYSFCYVEVWTHLGMKAAAIGMTCLHLIIVILLWIIWAQIIMMGPGRQPRVAPFMILPEMADAGERAKEGAATSVLPPDVYQCDTQGYPVWCSVCQSLKGLRTHHSVHLGFCVPRLDHYCVWLGTVIGRRNYRLFNQFLMCFLMHALIIFVSVVSLQRRIASSARMRGEREDPNVLVVLSLSCLVLLMVGALFISFLNYMANNQTTIEKLYTPKRQPRTMCFCVYNPADQYRYVVKSLPHENWNMWDKGSAYANYKDFLGSSIWRWFIPIGSNIPEFQTSAWEDDYNAILGPYKEELGSHYRDILMQRIEQGKYVTRLRVYGDKFREGL
What are the official names of this protein?
Palmitoyltransferase PFA5, Protein fatty acyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. PFA5 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS14_VIBVY
Sequence: MAKQSMKAREAKRAKLVAKFAEKRASLKAIISDVNVSEEDRWNAVLKLQTLPRDSSASRQRNRCNQTGRPHGYLRKFGLSRIKVREACMKGEIPGLRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PDX1_PLABE
Sequence: MRDYADNDSILLKHGWCEMLKGGVIMDVKNVEQAKIAEKAGAIGVMILENIPSELRNTDGVARSVDPLKIEEIRKCISINVLAKVRIGHFVEAQILEELKVDMLDESEVLTMADEYNHINKHKFKTPFVCGCTNLGEALRRISEGASMIRTKGEAGTGNIIEAIKHIRTVNNEIKYLCSLDESEVYNFAKKLRAPIDLILLTRKLKRLPVVNFAAGGIATPADAAMCMQLGMDGVFVGSGIFESENPQKMASSIVMAVSNFNNPKILLNVSLGLGKAMHGNTKVSNKWKNKSEEDNS
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by Pdx2.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit Pdx1, PLP synthase subunit Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: ORF11_TTVV3
Sequence: MAWYWWRRRRRRGWWKPRRRRWRRRRARRRGPARRHRARRRIVRHPCNGQTSSGNRVPRSVQAVDPKYVSLQLVWHSWDFRRGLFGQAGIKRMQQESDALTLSPVHRPKRPKRDTQVKEKTPEKDSDSAVQLRRLQPWIHSSQETKDEEEEIPEGPVQEQLLQQLQQQRLLRVQLESIAQEVLKIRRGHSLHPLLSSHA
What are the official names of this protein?
ORF1/1 protein.
Protein: BEXB3_HAEIF
Sequence: MQYGDKTTFKQSLAIQGRVINALLMREIITRYGRQNIGFFWLFVEPLLMTFFIVMMWKFIRADKFSTLNMIAFVMTGYPMAMMWRNASNRAIGSISANLSLLYHRNVRVLDTIFTRVLLEVAGASIAQILFMAILVMIDWIDAPHDVFYMLIAWFLMAMFAFALGLIICAIAQQFDVFGKIWGTLSFVLLPISGAFFFVHNLPAQAQSIALWFPMIHGTEMFRHGYFGDTVVTYESIGFLVVSDLALLLLGLVMVKNFSKGVEPQ
What is the function of this protein?
May form an ATP-driven capsule polysaccharide export apparatus, in association with the BexA, BexC and BexD proteins.
What are the official names of this protein?
Capsule polysaccharide export inner-membrane protein BexB.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NVD_HEMPU
Sequence: MASFCASKFLPGLLMLGLGLAVALASSTPTLSLLKDNLKVMNMPLGDWLHILATNFTNFVASQTLLTLTIFGVASFILRYLYQLFLKPLNLDRALGDVGYVLDGKKKRDVVNDIRRRRKSGDLPPIYPNGWIPLVASQDLVKGDVKYISAVGNEFAVYRGEDGEAYAVDAYCPHLGANMAIGGMVKGNCLTCPFHGWVFEGKEGKCVDIPYQEKGKSVPAQAKVKSWSVIEQNGFVLVWHDVEGREPSWFPENIEEEKWGKMYYHGTTKHTVCAHVEEISENGADCAHLTFVHGAFMGSGNDLRYMGSKLWSWASHSWGGKWEQDPDHKHVGVMTVYHAFSLFGMPIEVTRTESTARQNGPAHVLLSFSLPFGKATIAIGVTPIEPLTQIVTQHVYASRFIPRWLAKSFLYAEYVQFERDIMVWNYKTYQRKPLLVFEDRLISKHRRWYSQFFSENSPKFEDMKKTLDW
What is the function of this protein?
Catalyzes the production of 7-dehydrocholesterol (7-DHC or cholesta-5,7-dien-3beta-ol) by inserting a double bond (desaturating) at the C7-C8 single bond of cholesterol.  Essential regulator of steroid biosynthesis as this reaction is the first step in the synthesis of the steroid hormone Delta(7)-dafachronic acid.
What are the official names of this protein?
Cholesterol 7-desaturase nvd, Neverland, Nvd_Hp.
What is the protein family that this protein belongs to?
Belongs to the cholesterol 7-desaturase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RPO11_AERPE
Sequence: MERLRIIRESRGSYVIQVYGEDHTLGTLLVEAIKRVSNPKLAYYEAVHPMEDIIQVYVKYEDDVDIKEVLRKASDYLLEVIGDFRRRYLEALERRGGGG
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBL13_ARATH
Sequence: MATTSHNKPSLFPLLSLLCFISIFLLLSLSKRASLSSPKTHRSATVFPPKPDGSLSPLSATCDFSEGSWIYDPNPRSTRYTSSCKEIFKGWNCIRNNKTNGFEISNWRWKPKHCDLPSFDPLKFLQSHRNTNIGFVGDSLNRNMFVSLFCMLKSVTGELKKWRPAGADRGFTFSQYNLTIAYHRTNLLARYGRWSANAKGGELESLGFKEGYRVDVDIPDSSWAKASSFHDILILNTGHWWWAPSKFDPVKSPMLFFEGGRPILPPIPPATGLDRVLNNMVNFVEKTKRPGGIIFFRTQSPRHFEGGDWDQGGTCQRLQPLLPGKVEEFFSVGNNGTNVEVRLVNQHLYNSLKSRSAFHVLDITRMSEYRADAHPAAAGGKNHDDCMHWCLPGLTDTWNDLFVATLHTIKAL
What is the function of this protein?
May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).  May be involved in the specific O-acetylation of cell wall polymers (By similarity).
What are the official names of this protein?
Protein trichome birefringence-like 13.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: SYI_DICNV
Sequence: MADYKHTLNLPQTDFPMRGNLAQREPEQLRWWQEHEIYRKQREAFADCPTFMLHDGPPYANGQIHVGHALNKTLKDIIIKSRHLLGYNSPYVPGWDCHGLPIEQKVEQKIGKPNQKVSATEFRAACRRYAAEQVALQKDGFMRLGIFGFWDQPYLTMNFETEAQIVRALRDIVAAGHVTQGFKPINWCFDCASSLAEAEVEYQDKTSYSIDVAFAVKDVAALAKIMHADVVPAAVDVVIWTTTPWTLPANVAVSIHPEFYYVLVEIEGWYCVVAEELIPALKSRWKKSADWRICGRALGKDLDRLTLRHPFIDRDVLLINGTHVTLDAGTGCVHTAPAHGVEDYDVCQQYGIDLIHCVLGNGLYNDDTPHFAGQHIFAAEPQIIELLQTQNRLIAVEKITHSYPHCWRHKTPTIYRATTQWFISMDKAGLRQKALDGLNEVAFTPDWGKPRLLNMIAHRPDWCISRQRYWGVPLCFVVDKQTGQLHPDIVNIMDKAASAIEQKGVEAWYELSLDTLLSGKEVDRYEKLNDVLDVWFDSGTTHYSVLKKRAELSYPADLYLEGSDQHRGWFHSSLLTASAITGKPPYKALLTHGFTVDEDGRKMSKSLGNVVDPNQVIKTLGADILRLWVASADYTAEVSLSPNILNQRADAYRRMRNTCRFLLANLHDFDPEKNSVAYEKLLPLDRYVIAVAHDLQEKIKKLYVSYDFHLIYQEIFNFCSVMLGGFYLDVIKDRQYTVAQNALARRSAQTAIFHIIEAMVRWLAPILSFTAEEIWRYLPGKREESVFLTKFYEGLQPLNDDFLSMHDWELLLQLREKVNAALEKARNQGIIGGSLEAMVVLHLPPQEYEIAARFEQELRFILIVSAVNVQPSAALSIEVQHAIGEKCERCWHYLPDVGTDHQHPTLCKRCIENVDGGGELRRFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_HELHP
Sequence: MADITDIKSILYTEKSLSLQESGVLVVQTATNVSKNQLKEIFKEYFGITPLRINSLRQEGKVKRFRGKIGQRASFKKFYVKIPEGAKLDALSV
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: TMM18_XENLA
Sequence: MAEEPGVWSLLERAPIDWTEPWLIGLAAFHILCFIVTYISFKSYPLQICHFLLMVVLVSCAEYINEFAAMHWRAYSKQQYFDSSGMFISLAFSAPLLCNTIIIVVHWVYKTLCVMTELKTLQQKRKESREKRKKKE
What are the official names of this protein?
Transmembrane protein 18.
What is the protein family that this protein belongs to?
Belongs to the TMEM18 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein.
Protein: SEC24_ASPFU
Sequence: MASQQGGYPPQEGYGQPAGYGSPTQQHAGMAAGAPVQGHAGGKKKRAYAGEAFEIGSGANAALGGQLPAGGSYGAYPPQPQAAGYQQPVYGADPSQMNAAAPGYTAPVTPGIAQMTQQFGAMGVTDPHLMPPQPPQAAVAPQAPRPVPLNQLYPTDLLTQPFNVAELDYPPPPIVLPPGTSVYPSPTANCPPKYVRSTLNAVPTTHSLLKKSKLPFALVIQPYASLRDAEDPIPVIPDQVISRCRRCRSYINPFVTFLDHGHRWRCNMCNLTNDVPQAFDWDAALQKPADRSLRPDLNHAVVEFVAPQEYMVRPPQPLVYLFLIDVSYASVTNGLLATSARCIKESLDRIPNADRRTRLGFIAVDSSLHYFSIPRDGSENSDPRMLVISDLDEPFLPIPGDLLVTLSECRENIETFLDKLQEMFQNTQNNGCAMGSALRAGYKLIAPVGGKMTVLSSSLPNVGHGSLTMREDKKVLGTSKESSLLQTANSFYKSFAVECSKAQVSVDMFLFSSQYQDVASLSNLPRYTGGQTYFYPGWNAARGEDAIKFAREFSEYLSSEIGLEAVLRVRATTGLRMNTFYGNFFNRSSDLCAFPAFPRDQAYVVEVAIDETVTKPIVCLQTAVLHTTCNGERRIRVLTLALPTTQNLADVYASADQQAIATYFSHKAVERVLSSGLEPAREALQAKAVELLSTYRKELAGGSVSGGGLQFPANLRGLPVLFLAMIKNLGLRKSAQIPTDMRSAALCLLSTLPLPLLIQYIYPKMYSLHDMPDIAGLPDEQTGEIVLPPPVNLSSERIVPYGLYLIDDGQTQFLWVGRDAVPQLLLDVFGLPDRSQLRVGKQNLPELDNDFNQRVRAVIEKSRDHRSKGVGSIVVPHLYVVKEDGEPGLRLWAQTMLVEDRADQSVSLVQWMGSLREKV
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec24.
What is the protein family that this protein belongs to?
Belongs to the SEC23/SEC24 family. SEC24 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: IRE1_ORYSJ
Sequence: MRSLRRVLLQLVLLAGVAFRGVRFDDAADAAAAAQGSSDLFELPSPSPTLALPGGGDEGASTEIIAAPWPGRHGLFTPPRSTSQPARAVVQPAADFGSQLQFYDNGTIQLVDLLSKLPRWQFSTGPPLSKHITTSKPDLNYVIYLDGSETSDLIEVHNGSGVRLPWKLEEFIAETPYIRDSFVTIGSKVSTTFVVNADSGEIIYKHSLPVALNEVGGPLVEEIPSKLDAARSGTSANIIVVVRTDYSISASDLGEHLFNWTRTSFTANYYARYGHQDMLAQSSCLRGNIPCIRTEGPPIKLYLPDSSSDNAIVLRPVNEVSAVDALEPLLPPKKLPQPAGESNVALDSAQNQTADIALGHFVPADTELTNSVTKFSYRWLFPTFLMLLIMACLVKLADASKYCRQFVIRFLKPFMRDEKLMDPRGKSEGTSKRRKARKKDGLINSTQIFSASDKEGNGTGGSTEAQSNKAHDSTNVELPNGLNGRQIGKLCVYSKEIGKGSNGTVVFEGSYGGREVAVKRLLRSHNDIASKEIENLIASDQDPNIVRMYGFEQDNDFVYISLERCRCSLADLIQLHSVPPFSNTKGTDIELWRQDGLPSAQLLKLMRDVVAGIVHLHSLGIIHRDLKPQNVLISKEGPLRAKLSDMGISKRLQEDMTSVSHHGTGFGSSGWQAPEQLRHGRQTRAIDLFSLGCLIFYCITKGKHPFGEYYERDMKIINNQFDLFIVDHIPEAVHLISQLLDPDPEKRPTAVYVMHHPFFWSPELCLSFLRDTSDRIEKTSETDLIDALEGINVEAFGKNWGEKLDAALLADMGRYRKYSFESTRDLLRLIRNKSGHYREFSDDLKELLGSLPEGFVQYFSSRFPKLLIKVYEVMSEHCKDEEAFSKYFLGSSA
What is the function of this protein?
Involved in endoplasmic reticulum (ER) stress response.  Senses unfolded proteins in the lumen of the ER via its N-terminal domain which leads to enzyme auto-activation.  The active endoribonuclease domain splices bZIP50 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response (UPR) transcriptional activator, which then induces transcription of UPR target genes, such as luminal-binding protein (BiP) chaperones.
What are the official names of this protein?
Serine/threonine-protein kinase/endoribonuclease IRE1, Endoplasmic reticulum-to-nucleus signaling 1, Inositol-requiring protein 1, OsIRE1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: MODC_MYCTU
Sequence: MSKLQLRAVVADRRLDVEFSVSAGEVLAVLGPNGAGKSTALHVIAGLLRPDAGLVRLGDRVLTDTEAGVNVATHDRRVGLLLQDPLLFPHLSVAKNVAFGPQCRRGMFGSGRARTRASALRWLREVNAEQFADRKPRQLSGGQAQRVAIARALAAEPDVLLLDEPLTGLDVAAAAGIRSVLRSVVARSGCAVVLTTHDLLDVFTLADRVLVLESGTIAEIGPVADVLTAPRSRFGARIAGVNLVNGTIGPDGSLRTQSGAHWYGTPVQDLPTGHEAIAVFPPTAVAVYPEPPHGSPRNIVGLTVAEVDTRGPTVLVRGHDQPGGAPGLAACITVDAATELRVAPGSRVWFSVKAQEVALHPAPHQHASS
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y687_THEMA
Sequence: MKKIKSFGGKSLGGGKQEKILKDFARMQEELQKKIQELEESFSQIEVEASVGGGAVRIVATCDRRVKDIEIDEDLKEDFDTLKDLLIAGMNEVMEKIEKRREEEMSKITQQFGIPGLM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein TM_0687.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: NDHK_LOTJA
Sequence: MNSIEFPLIDRTTQNSVISTTLNDLSNWSRLSSLWPLLYGTSCCFIEFASLIGSRFDFDRYGLVPRSSPRQADLILTAGTVTMKMAPSLVRLYEQMPEPKYVIAMGACTITGGMFSTDSYSTVRGVDKLIPVDVYLPGCPPKPESILDAITKLRKKISREIHEDQTSSLSSQRENRCFTTNHKFYVERSTHTGNYDQVLFHQPPSTSEISSDTFFRYQKVQYPPRNEIVN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K, chloroplastic, NAD(P)H dehydrogenase subunit K, NADH-plastoquinone oxidoreductase subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: RPIA_STRMU
Sequence: MEELKKIAGVRAAQYVEDGMIVGLGTGSTAYYFVEEVGRRVQEEGLQVIGVTTSSRTTAQAQALGIPLKSIDEVDSVDVTVDGADEVDPNFNGIKGGGGALLMEKIVGTLTKDYIWVVDESKMVDTLGAFRLPVEVVQYGAERLFREFEKKGYKPSFREYDGVRFVTDMKNFIIDLDLGSIPDPIAFGNMLDHQVGVVEHGLFNGMVNRVIVAGKDGVRILEANK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PAG1_SHEEP
Sequence: MKWLVLLGLVAFSECIVKIPLRRVKTMRNTLSGKKMLNSFLKEHAYRLSQISFRASNLTIHPLRNIMDMLYVGNITIGTPPQEFQVVFDTGSSDLLVPSINCLSPTKRPCSKQDKFKHHQSSTFRFTNDTFRIYFGSGTMRGFVAHDTVRIGDLVSTDQPFGLIFLESWLDIPFDGILGLNYPKISFSGAIPIFDKLKNEGAFSEPVFAFYLNKDKQEGSVVMFGGVDHRYYKGELNWVPLIHPGEWSIPLDRISMRRKVIACSGGCEALVGTGTSLILGPRTVVENIQKHIGATQQCFEYFVSCSAVYALPSIVFTINGINYPVPPQAYLVKDSRGQCYSPFQVNRANPSAENWILGDVFLRRYFSVFDRGNDRIGLARAV
What is the function of this protein?
Has no proteolytic activity.
What are the official names of this protein?
Pregnancy-associated glycoprotein 1, PAG 1, Inactive aspartic protease PAG-1, Pregnancy-associated glycoprotein 66d, ovPAG 66d.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.