PharMolix/UniProtQA huggingface dataset:
Protein: FALX3_LITFA
Sequence: MASLKKSLFLVLFLGLVSLSICEEKKRENEDDAEDENHEEESEEKRGLLDFAKHVIGIASKLGKRSEEKRYHPFGKRSEEKRYFPIPFGKRSEEKRYFPIPIGKRSEEKRYFPIPIGKKKKKK
What is the function of this protein?
Fallaxidin-3. 2 shows antibacterial activity against the Gram-positive bacteria E. faecalis (MIC=100 uM) and L. lactis (MIC=500 uM).  No antibacterial activity against the Gram-positive bacteria B. cereus, L. innocua, M. luteus, S. epidermidis, S. uberis and S. aureus, or the Gram-negative bacteria E. cloacae and E. coli.
What are the official names of this protein?
Preprofallaxidin-3.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAK_SHESA
Sequence: MGKIIGIDLGTTNSCVAVLDGGKARVLENAEGDRTTPSIIAYTDDETIVGQPAKRQAVTNPNNTFFAIKRLIGRRFKDDEVQRDVNIMPFKIIAADNGDAWVESRGNKMAPPQVSAEILKKMKKTAEDFLGEEVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAYGIDKKQGDNIVAVYDLGGGTFDISIIEIDSNDGDQTFEVLATNGDTHLGGEDFDNRLINYLADEFKKEQGLDLRKDPLAMQRLKEAAEKAKIELSSTNQTEVNLPYITADATGPKHLVVKITRAKLESLVEDLIIRTLEPLKVALADADLSVSDINEVILVGGQTRMPKVQEAVSNFFGKEPRKDVNPDEAVAVGAAIQAGVLSGDVKDVLLLDVTPLSLGIETMGSVMTKLIEKNTTIPTKAQQVFSTADDNQSAVTIHVLQGERKQASANKSLGQFNLDGIEPAPRGMPQIEVMFDIDADGILHVSATDKKTGKKQNITIKASSGLSEEEVAQMVRDAEAHAEEDKKFEELVQSRNQADGLVHATKKQVEEAGDALPADDKAKIEAAMSAVEVATKGNDKEAIEKATQELIEASAKLMEIAQAKAQTQGGAQEGAAKQSNATADDVVDAEFEEVKDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: SYS_ACIBC
Sequence: MIDPKLLRNNIEVVNAALAKRGVQLDVQEWASLETRRKDLQSKTEKLQAERNAGAKQVGQIKKSGGDASEIMARMQAIGDEIKAAEVALSELQNEIEQKALSIPNLPDESVPAGKDENDNVEISKWGTPRQFDFEIKDHTDLGEWMGGLEFETATKLTGSRFSVLKGPLARLQRALTQFMLDTHTLKNGYTEAYVPYLVNADSLRGTGQLPKFEEDLFKLQGEKEYYLIPTAEVPVTNFVRDEIIDADRLPLKYAAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQIVKPETSMQALEELTAHAEGILQALGLPYRKILLCGGDMGFGATKTYDLEVWVPSQNTYREISSCSNMGDFQARRMKARYRMDQKKTELVHTLNGSGLAVGRTLLAVMENYQRKDGSIEIPEVLRPYMGGATFID
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMM_ECO45
Sequence: MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYTGYSYSSNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTCSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_VIBC1
Sequence: MQELRFVLIVVGALAIAALLFHGLWTSKKEGKAKFGNKPLGKLDVDQEDKDTPGQERDFAPDPEDDFEIIRKDRKEPDFGMENSFDNKFSSDPLIDDVLEAKEDKEQREEQEIPAFVATKTDDEQVEPVLQEPAKAFAEKEEAAEVVEETLQPVFEAPLAAQAPEVEVAPVVVDPVVEEPKPEPEMQVIVLNVHCAGDEPFVGTQLFDSMQQNGLIYGEMNIFHRHVDLSGNGKVLFSVANMMQPGTLEHGDPAEFSTKGISFFMTLPCYGEADQNFNLMLRIAQQIADDMGGNVLDDQRNLMTPDRLASYRRQIVEFNAANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: SAHH_MYCUA
Sequence: MTTTETSLSADTKNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPEEPKGVPVFAWKGESLEEYWWCAEQMLTWPDSDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDSAEWKVFLGLLRSRFETDKGKWTKIAESVKGVTEETTTGVLRLYQFAEAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEDAIGDADIVVTSTGNKDIIMLEHIKAMKDHSILGNIGHFDNEIDMAGLERSGATRTNIKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGRLTKLTKDQAEYLGVDVEGPYKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_ECOSE
Sequence: MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQGLETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP7_ROTBJ
Sequence: MYGIEYTTILIFLVSIILINYILKSITRIMDYIIYRFLFVVVLMAIVTSAQNYGVNLPITGSMDTAYANSTQNEPFLTSTLCLYYPIEASNEIADTEWRNTLSQLFLTKGWPTGSVYFKEYADIAAFSVEPQLYCDYNIVLMKYDSTLELDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCSTTNPDTFETVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGANILDITADPTTAPQTERMMRVNWKKWWQVFYTVVDYVNQIIQAMSRRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: SIM1_HUMAN
Sequence: MKEKSKNAARTRREKENSEFYELAKLLPLPSAITSQLDKASIIRLTTSYLKMRVVFPEGLGEAWGHSSRTSPLDNVGRELGSHLLQTLDGFIFVVAPDGKIMYISETASVHLGLSQVELTGNSIYEYIHPADHDEMTAVLTAHQPYHSHFVQEYEIERSFFLRMKCVLAKRNAGLTCGGYKVIHCSGYLKIRQYSLDMSPFDGCYQNVGLVAVGHSLPPSAVTEIKLHSNMFMFRASLDMKLIFLDSRVAELTGYEPQDLIEKTLYHHVHGCDTFHLRCAHHLLLVKGQVTTKYYRFLAKHGGWVWVQSYATIVHNSRSSRPHCIVSVNYVLTDTEYKGLQLSLDQISASKPAFSYTSSSTPTMTDNRKGAKSRLSSSKSKSRTSPYPQYSGFHTERSESDHDSQWGGSPLTDTASPQLLDPADRPGSQHDASCAYRQFSDRSSLCYGFALDHSRLVEERHFHTQACEGGRCEAGRYFLGTPQAGREPWWGSRAALPLTKASPESREAYENSMPHIASVHRIHGRGHWDEDSVVSSPDPGSASESGDRYRTEQYQSSPHEPSKIETLIRATQQMIKEEENRLQLRKAPSDQLASINGAGKKHSLCFANYQQPPPTGEVCHGSALANTSPCDHIQQREGKMLSPHENDYDNSPTALSRISSPNSDRISKSSLILAKDYLHSDISPHQTAGDHPTVSPNCFGSHRQYFDKHAYTLTGYALEHLYDSETIRNYSLGCNGSHFDVTSHLRMQPDPAQGHKGTSVIITNGS
What is the function of this protein?
Transcriptional factor that may have pleiotropic effects during embryogenesis and in the adult.
What are the official names of this protein?
Single-minded homolog 1, Class E basic helix-loop-helix protein 14, bHLHe14.
What are the subcellular locations of this protein?
Nucleus.
Protein: VATE_THET2
Sequence: MSKLEAILSQEVEAEIQALLQEAEAKAEAVKREAEEKAKALLQARERALEAQYRAALRRAESAGELLVATARTQARGEVLEEVRRRVREALEALPKKPEWPEVVRKLALEALEALPGAKALVANPEDLPHLEALAKERGVELKAEPALRLGVRAVGAEGKTQVENSLLARLDRAWDALSSKVAQALWG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: PLD3_RAT
Sequence: MKPKLMYQELKVPVEEPAGELPMNEIEAWKAAEKKARWVLLVLILAVVGFGALMTQLFLWEYGDLHLFGPNQHPAPCYDPCEAVLVESIPEGLEFPNATTSNPSTSQAWLGLLAGAHSSLDIASFYWTLTNNDTHTQEPSAQQGEEVLQQLQALAPRGVKVRIAVSKPNGPLADLQSLLQSGAQVRMVDMQKLTHGVLHTKFWVVDQTHFYLGSANMDWRSLTQVKELGVVMYNCSCLARDLTKIFEAYWFLGQAGSSIPSTWPRPFDTRYNQETPMEICLNGTPALAYLASAPPPLCPGGRTPDLKALLSVVDNARSFIYIAVMNYLPTMEFSHPRRFWPAIDDGLRRAAYERGVKVRLLISCWGHSEPSMRSFLLSLAALRDNHTHSDIQVKLFVVPADEAQARIPYARVNHNKYMVTERTTYIGTSNWSGSYFTETAGTSLLVTQNGHGGLRSQLEAVFLRDWESPYSHNLDTSADSVGNACRLL
What is the function of this protein?
5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA) (By similarity).  Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor in collaboration with PLD4 (By similarity).  May be important in myotube formation.  Plays a role in lysosomal homeostasis.  Involved in the regulation of endosomal protein sorting (By similarity).
What are the official names of this protein?
5'-3' exonuclease PLD3, Choline phosphatase 3, Phosphatidylcholine-hydrolyzing phospholipase D3, Phospholipase D3, PLD 3.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Lysosome lumen. Early endosome membrane; Single-pass type II membrane protein. Late endosome membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. Endosome membrane; Single-pass type II membrane protein. Note=Localizes to ER-associated vesicles in differentiating myotubes. The soluble form in lysosome arises by proteolytic processing of the membrane-bound form.
Protein: METE_PYRFU
Sequence: MELPILPTSVIGSYPKPRWLLRMYKLRELGKIPEEDFKEAVRDASISVLREHERAGIDIPWDGEMGRSEMTEYFTSKIKGFKFYGPVRVWGNAYFNKAAAVDKLEYEEPLVLDEFLWVKENTTREIVKIPITGPYTIAEWSFNEYYPDKESFVMDLAEIINKELKVLEKHGAKFVQLDEPAMLNHPSEVPLAVDAINRAVKGIKMKVGLHVCYSNYNLLADYFDEIKVTQFALEFANRNFRDMDFLKKLSNKELGFGVVDVHNPRVESVEEIRQAIKKVFTYLEPEWVYINPDCGLKLLDRKIAYQKLVNMVQAVRGVRKELEKEGKTTIEFRTLKDI
What is the function of this protein?
Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation.  The physiological methyl donor is unknown.
What are the official names of this protein?
Methionine synthase, Homocysteine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the archaeal MetE family.
Protein: DSBB_VIBAL
Sequence: MTILNSLNQFSKGRLSWLLLLLFVVFFEACALYFQHVMMLAPCVMCIYERVAMMGVGVAAIVGLMAPNNPIFRWLGLIGWGLSSYKGLLLAQQHVDYQFNPSPFATCDLFVTFPSWRPLNQWAPWIFEAYGDCSKIVWQFLDLSMPQWLVVIFAGNLIALALIVI
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GNA1_PONAB
Sequence: MKPDETPMFDPSLLKEVDWSQNTATFSPAISPTHPGEGLVLRPLCTADLNRGFFKVLGQLTETGVVSPEQFMKSFEHMKKSGDYYVTVVEDVTLGQIVATATLIIEHKFIHSCAKRGRVEDVVVSDECRGKQLGKLLLSTLTLLSKKLNCYKITLECLPQNVGFYKKFGYTVSEENYMCRRFLK
What are the official names of this protein?
Glucosamine 6-phosphate N-acetyltransferase, Phosphoglucosamine acetylase, Phosphoglucosamine transacetylase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GNA1 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein.
Protein: NADC_ARCFU
Sequence: MPYGDVTAIPTKDVEAVIVSKGEGVLAGVGVVKILFDLAEIVVMESKKDGEPIKPGDVVMRLRGKSDSILATERLAINILMRMSGIATATAKMVERARRVNPKVVVAATRKTTPGFRIFEKMAVEIGGGDAHRFSLSDCLMLKDNHIAVAGSLERAMKVKRSFTKKLEVEVGSVGDAIKAAEFGADIIMLDNFTPEMVAEAVEELRRRGLREKVIIEVSGSVTPENVAEFAAMDVDVISSGYITHSAPALDFSLRVLQ
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Probable nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: UL139_HCMVM
Sequence: MLWILVLFALAASASETTTGTSSNSSQSTSAGTTNTTTPSTACINASNGSDLGAPQLALLAASGWTLSGLLLIFTCCLCCFWLVRKVCSCCGNSSESESKATHAYTNAAFTSSDATLPMGTTGSYTPPQDGSFPPPPR
What are the official names of this protein?
Membrane glycoprotein UL139.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: HSPB8_MACMU
Sequence: MADGQMPFSCHYPSRLRRDPSGLSLSSRLLDDGFGMDPFPDDLTASWPDWALPRLSSAWPGTLRSGMVPRGPTATARFGVPAEGRTPPPFPGEPWKVCVNVHSFKPEELMVKIKDGYVEVSGKHEEKQQEGGIVSKNFTKKIQLPAEVDPVTVFASLSPEGLLIIEAPQVPPYSTFGESSFNNELPQDSQEVTCT
What is the function of this protein?
Displays temperature-dependent chaperone activity.
What are the official names of this protein?
Heat shock protein beta-8, HspB8, Protein kinase H11.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock.
Protein: SPNXB_HUMAN
Sequence: MGQQSSVRRLKRSVPCESNEANEANEANKTMPETPTGDSDPQPAPKKMKTSESSTILVVRYRRNVKRTSPEELLNDHARENRINPDQMEEEEFIEITTERPKK
What are the official names of this protein?
Sperm protein associated with the nucleus on the X chromosome B1, Cancer/testis antigen 11.2, CT11.2, Nuclear-associated protein SPAN-Xb, SPANX-B, SPANX family member B1, SPANX family member F1.
What is the protein family that this protein belongs to?
Belongs to the SPAN-X family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Associated with nuclear craters.
Protein: VF123_ASFP4
Sequence: MPSTGTLVIIFAIVLILCIMLLFFYKTAEAGKSGVLPPPIPPPTPPPPKKKYDHNEYMEKTDLEPEVKKNHRKWANEAEHLISSSVKGLENLDETAFLANHKGHGFRTFDHAKSLFKEFLKKY
What are the official names of this protein?
Uncharacterized protein CP123L, pCP123L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus CP123L family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein. Virion.
Protein: RS18_PSEMY
Sequence: MARFFRRRKFCRFTAEDVKEIDFKDLNTLKAYISETGKIVPSRITGTKARYQRQLATAIKRARFLALLPYTDSHGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TSG13_MOUSE
Sequence: MGPKKNSKFQEVSGSKPVGNVSIRFEKQLGQDDEEMYDTTAQSKFVLKNLRHYTVHPNMAKYYEPLKPTKLQRFLTQKKKMNSFMLKVTEYDQDMTLLLMTNNPPPCSISQEKDGAPIYFPPEFQLKETLHRCKPNKNDFFPTMSQKKKLKPELKPVFPMKRLDDPTFKGQQWFRFSTDNDFNIEGKYSEIYALRKQKKMYPNLIFAPASQRETKKHVSMKSESETPTSQVFWEPLTFSKLLEEKPTRSVPGESFFRHGRAQQWIVKDAAVIW
What are the official names of this protein?
Testis-specific gene 13 protein.
Protein: SXA1_SCHPO
Sequence: MKASFFVFAISALQALQASVASAYSEVPGKRSVVLNLQHSQYDHVARKLERTKVLNKRDSSGYPVLDLEYTDAGGYFANLTLGSNERVYSLTLDTGSPYTWVTAKNITALSASEIWSDTDGVDAGRSTSDIRTNACTNYTCFDYSSTTARRTNSSTIGFLASYGDNTTVLGYNMVDNAYFAGLTLPGFEFGLATREYDSSQISVTPGIIGLSVAMTITGISSDDKVVAFTPPTIVDQLVSANVIDTPAFGIYLNEDVGELIFGGYDKAKINGSVHWVNISSSDDSTFYSVNLESITVTNSTSSNNVQSSKRSSKDIEVNTTVTLDTGTVYIYLPEDTVESIADQYQGIVSEYGYVVIYCDSFSDSDYISFNFGSDADFHVSVNDLVIYRQESTSGDICYLALFEGDTSSYLLGQYFLQYVYSIYDWDAQKIGLAALNSNATSTANHQILNINSALRSVTSGQSVSATPTVSMSIAATSFGSSLVLTASASPSSTSVDGSSSSDSSEASGAASVGVSISAIVLCASTLISLLFA
What is the function of this protein?
Involved in degradation or processing of the mating pheromones.  Its loss may cause a persistent response to the pheromones.  It may cleave the mating pheromone M-factor.  May be involved in processing of zymogens that are required for zygote formation.
What are the official names of this protein?
Aspartic proteinase sxa1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
Protein: ADDL_TREPS
Sequence: MKSLEYYRSQPKADVHTHLNLSMKYERYKQWSGVVIPNFPRKMRGLDEMHEIIGEYTRPQCKTAQDVLNLFTMSIEDAIADNVVVMETSVDIGFITHYEENLDHFLCDLSDLHRRYKRNVTLHFELGISKIRERSFVEQWAEPMMRSGIFENIDLYGPEISEGIEDFIYIFKLAEKYHLKKKAHVGEFSDAQSVRHFVEIFNLDEVQHGIGAATDENVLRFLAERKVRCNVCPTSNVMLNAVECLEKHPIKKMMDAGVRVGLGTDDLLFFGKTNSEQLFDMVSCGLITELHAEALLAVR
What is the function of this protein?
Putative nucleoside deaminase.  May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism.
What are the official names of this protein?
Putative adenosine/adenine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: ACKA_PSECP
Sequence: MLVLVINSGSSSLKFQVRDVAAGTVLTEGLIEKIGMGNGGDGDGEIVGPRDHAEALEQVEAAIHEELGDLKLGAVGHRVVHGGERFGEPVLIDNEITRAIERLNPLAPLHNPANVLGIRAITRKWPDMPQVAVFDTAFHRTLPEHAWRYAVPDELYTNHGIRRYGFHGTSHEYVARRAAALLDLPVEEFDAVIAHLGNGASITAIQGGHSVDTSMGFTPLEGLVMGTRSGDLDPSILVFLGRAGWTPEDLDSMLNRESGLKGLAGNNDMRSVVEASEDGDAKAAMALAVTSYRLAKYIGGYHVAVGGAKALVFTAGIGENSHQFRALVADRLGALGVEVDAGLNAARSKEPRIISTPQSAIPVLVVPTDEERAIAEATAAVAGSGR
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_KLEP3
Sequence: MKSLTLIPGKLSLSQLREVYSHPLNITLDSSAFAAIDESVACVNAILAEGRTAYGINTGFGLLAQTRISTDDLENLQRSLVLSHAAGVGEPLDDDLARLIMVLKINSLSRGFSGIRLSVIQALIGLVNAGVTPWIPAKGSVGASGDLAPLAHMSLTLLGEGKARVRGGEWLPATDALRQAGLEPITLAAKEGLALLNGTQASTAFALRGLFEAEDLFASAVVCGALTTEAALGSRRPFDARIHEVRGQRGQIDAAALYRHLLTDDSAISRSHHNCTKVQDPYSLRCQPQVMGACLTQIRQAAEVLLAEANAVSDNPLVFAAENDVISGGNFHAEPVAMAADNIALAIAEIGSLSERRIALMMDSHMSQLPPFLVKNGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGRRLWAMAENTRGVLAVEWLAAAQGLDMREGLTTSPLLEEARHLLRERVPHYTQDRFFAPDIENAIALLAARHLTRLLPAVLH
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_CHLT2
Sequence: MALRFEILHQSKKSRARVGRIETAHGYIDTPAFVPVATNGALKGVLDHSNIPLMFCNTYHLIVHPGAEAIAAMGGLHQFIGRNAPIITDSGGFQIFSLAYGSVAEEIKSCGKKKGGNTIIKVNDDGVHFKSYRDGRKLFLSPEISVQAQKDLGADIILPLDELLPFHADPTYFHQSSQRTYVWEKRSLDYHLKNPGIQSMYGVIHGGTFPDQRKLGCKFVEDLPFDGSAIGGSLGKNLQDIVEVVGVTAANLSAERPRHLLGIGDLPSIWATVGFGIDSFDSSYPTKAARHGMILTSQGPLKINNQRYSSDLNPIEPGCSCLACSQGITRAYLRHLFKVHEPNAGIWASIHNMHHMQKVMREIREGILNDRI
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: PYRC_ALKEH
Sequence: MQRITLTRPDDWHLHLRDGEQLATVLPHTATVFGRAIIMPNLKPPVTTVDQAAAYRERILAALPAGAHFEPLMTLYLTDNTPPAEIEKAAASGFVHAVKLYPAGATTNSDAGVTDLARCEETLAAMAERGLPLCVHGEVTRDEVDIFDREAHFIDEVLDPLVQRHSRLRVVFEHITTQAAVDYLRQAPDRVGATLTVQHLMANRNHMLVGGVRPHYYCLPILKRERDRQALVEAATSGHPRFFLGTDSAPHPKGAKESACGCAGVYSAHAALPFYAEIFEAAGALDRLEGFASHHGADFYGLPRNRDSVTLERAATPIPEAFPMGDDTLVPFRAGGEVAWRVV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: PYRB_MACCJ
Sequence: MKHLHSITELSNDEIMHTIERAIMIKNGEIKRYENIYTANLFFENSTRTKCSFEMAERKLGLQVIPFETSTSSVTKGESLYDTCKTLESIGCDVLVIRHPENNYYEQLHELNIPVVNGGDGSGQHPTQCLLDLMTIYEEYGKFEGLKIIICGDILNSRVARSNYHALTSLGAQVKFVAPEIWQDHSLDAEYVSIDDAIEEVDVCMLLRVQHERHDEDAANFSRVNYNRMYGLTRERYDRLKEEAIILHPAPVNRDVEIDSELVEAPKSRIFKQMENGVYTRMSILSQVIENNR
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: YG3G_YEAST
Sequence: MYQLLFEIKVKIKIQTEKKKKLNIKLDIVGEGSCILFSINTNNKMIYLFSYFFLMSSGKKNINKYKKILVRNLKRVYAQCIYIARKKNKQWHYSACGWQCSSVAFSKNLECV
What are the official names of this protein?
Putative uncharacterized protein YGR139W.