Protein: LRP1_CHICK
Sequence: MGPLLALAGCLLALLAAPAARALEAPKTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTELCIHMSKLCNGLHDCFDGSDEGPHCREQLANCTALGCQHHCVPTLSGPACYCNNSFQLAEDRRSCKDFDECTVYGTCSQTCTNTEGSYTCSCVEGYLLQPDNRSCKAKNEPVDRPPVLLIANSQNILATYLSGAPVPNITPTSAKQTTAMDFNYIEDTVCWVHVGDSASQTILKCAKIPNLKGFVEERSINISLSLHQVEQMAIDWLTGNFYFVDDIDDRIFVCNKNGLTCVTLLDLELYNPKGIALDPAMGKVFFTDYGQIPKVERCDMDGQNRTKLVDSKIVFPHGITLDLVSRLVYWADAYLDYIEVVDYEGKNRHTIIQGILIEHLYGLTVFENYLYATNSDNANAQQKTSVIRVNRFNSTEYQVVTRVDKGGALHIYHQRRQPTVRSHACEPDQFGKPGGCSDICLLGNSHKSRTCRCRSGFSLGSDGKSCKKPEHELFLVYGKGRPGIIRGMDMGAKVPDEHMIPIENLMNPRALDFHAETGFIYFADTTSYLIGRQKIDGTERETILKDGIHNVEGIAVDWMGNNLYWTDDGPKKTISVARLEKAAQTRKTLIEGKMTHPRAIVVDPLNGWMYWTDWEEDPKDSKRGKIERAWMDGSNRNVFITSKTVLWPNGLSLDIPAKILYWVDAFYDRIEMVYLNGTERKIVYEGPELNHAFGLCHYSSFLFWTEYRSGSIYRLDQSSKAVSLLRNERPPIFEIRMYDAQQQQVGSNKCRVNNGGCSSLCLATPRGRQCACAEDQILGADSVTCEANPSYIPPPQCQPGEFACKNNRCIQERWKCDGDNDCLDNSDEAPELCHQHTCPSDRFKCKNNRCIPNRWLCDGDNDCGNNEDESNSTCSARTCSPNQFSCASGRCIPISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAGCSHSCSSNQFKCNSGRCIPVHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPMRWRCDGDTDCMDSSDEKNCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDEENCESLVCKPPSHTCANNTSICLPPEKLCDGSDDCGDGSDEGELCDQCSLNNGGCSHNCTVAPGEGIVCSCPLGMELGADNKTCQIQSYCAKHLKCSQKCEQDKYNVKCSCYEGWMLEPDGESCRSLDPFKPFIIFSNRHEIRRIDLHRGDYSVLVPGLRNTIALDFHLNQSSLYWTDVVEDKIYRGKLLENGALTSFEVVIQYGLATPEGLAVDWIAGNIYWVESNLDQIEVAKLDGTMRTTLLAGDIEHPRAIALDPRYGILFWTDWDASLPRIEAASMSGAGRRTIHKETGSGGWPNGLTVDYLEKRILWIDARSDAIYSALYDGTGHIEVLRGHEYLSHPFAVTLYGGEVYWTDWRTNTLAKANKWTGHNVTVVQRTNTQPFDLQVYHPSRQPLAPNPCEANGGKGPCSHLCLINYNRTLSCACPHLMKLDKDNTTCYEFKKFLLYARQMEIRGVDIDNPYYNYIISFTVPDIDNVTVVDYDAVEQRIYWSDVRTQTIKRAFINGTGVETVVSADLPNAHGLSVDWVSRNLFWTSYDTNKKQINVARLDGSFKNAVIQGLDKPHCLVVHPLHGKLYWTDGDNISVANMDGSNRTLLFTNQRGPVGLAIDYPESKLYWISSGNGTINRCNLDGSDLEVIVAVKSQLSKATALAIMGDKLWWADQASERMGTCNKKDGTEVTVLRNSTTLVMLMKVYDESIQQAGSNPCSVNNGDCSQLCLPTSETSRSCMCTAGYSLKSGQQSCEGVGSFLLYSVHEGIRGIPLDPNDKSDALVPVSGTSLAVGIDFHAENDTIYWVDMGLSTISRAKRDQTWREDVVTNGIGRVEGIAVDWIAGNIYWTDQGFDVIEVARLNGSFRYVVISQGLDKPRAITVHPEKGYLFWTEWGQYPRIERSRLDGTERMVLVNVSISWPNGISVDYEDGKLYWCDARTDKIERIDLETGENREVVLSSDNMDMFSVSVFEDYIYWSDRTHANGSIKRGSKDNATESVSLRTGIGVQLKDIKVFNRARQKGTNVCAQNNGGCQQLCLFRGGGRRTCACAHGMLSEDGVSCRDYDGYLLYSERTILKSIHLSDENNLNAPIKPFEDAEHMKNVIALAFDYRYGTKGSNRIFYSDIHFGNIQQINDDGTGRRTIVENVGSVEGLAYHRGWDTLYWTSYTTSTITRHTVDQSRLGAFERETVITMSGDDHPRAFVLDECQNLMFWTNWNEQHPSIMRATLSGANVLIIIDQDIRTPNGLAIDHRAEKIYFSDATLDKIERCEYDGSHRHVILKSEPVHPFGLAVYGDYIFWTDWVRRAVQRANKYVGTDMKLLRVDIPQQPMGIIAVANDTDSCELSPCRVNNGGCQDLCLLTPKGHVNCSCRGERVLQEDFTCKALNSTCNVHDEFECGNGDCIDFSRTCDGVVHCKDKSDEKQSYCSSRKCKKGFLHCMNGRCVASRFWCNGVDDCGDNSDEVPCNKTSCAATEFRCRDGSCIGNSSRCNQFIDCEDASDEMNCTATDCSSYFKLGVKGTTFQKCEHTSLCYAPSWVCDGANDCGDYSDERNCPGGRKPKCPANYFACPSGRCIPMTWTCDKEDDCENGEDETHCSERQDKFCYPVQFECNNHRCISKLWVCDGADDCGDGSDEDSRCRLTTCSTGSFQCPGTYVCVPERWLCDGDKDCADGADETLAAGCLYNNTCDEREFMCGNRQCIPKHFVCDHDDDCGDGSDESPECEYPTCGPHEFRCANGRCLSNSQWECDGEFDCHDHSDEAPKNPRCSSPESKCNDSFFMCKNGKCIPEALLCDNNNDCADGSDELNCFINECLNKKLSGCSQECEDLKIGYKCRCRPGFRLKDDGKTCIDIDECSTTYPCSQKCINTLGSYKCLCIEGYKLKPDNPTSCKAVTDEEPFLIFANRYYLRKLNLDGSNYTLLKQGLNNAVALDFDYREQMIYWTDVTTQGSMIRRMHINGSNVQVLHRTGLSNPDGLAVDWVGGNLYWCDKGRDTIEVSKLNGAYRTVLVNSGLREPRALVVDVQNGYLYWTDWGDHSLIGKIGMDGTNRSVIVDTKITWPNGLTLDYINSRIYWADAREDYIEFASLDGSNRHTVLSQDIPHIFALTLFEDYIYWTDWETKSINRAHKTTGANKTLLISTLHRPMDIHIYHPYRQPDVPNHPCKTNNAGCSNLCLLSPGGGHKCACPTNFYLGSDGKTCVSNCTASQFVCKNDKCIPFWWKCDTEDDCGDRSDEPEDCPEFKCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANCDIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDEKDCPEVTCAPNQFQCAITKRCIPRVWVCDRDNDCVDGSDEPANCTQMTCGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESCTPRPCSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCIPRCEFDQYQCKNGHCIPMRWRCDADADCMDGTDEEDCGTGVRTCPLDEFQCNNTLRKPLAWKCDGEDDCGDNSDENPEECLKFQCPPNRPFRCKNDRVCLWIGRQCDGIDNCGDNTDEKDCESPTAKPKSCSQDKNEFLCENKKCISANLRCNFFDDCGDGSDEKSCSHEHKSYDCMTNTTMCGDEAQCIQAQSSTYCTCRRGFQKVPDKNSCQDVNECLRFGTCSQLCNNTKGSHVCSCAKNFMKTDNMCKAEGSEHQILYIADDNKIRSMYPFNPNSAYEPAFQGDENVRIDAMDIYVKGNKIYWTNWHTGRISYCELPASSAASTASNRNRRQIDGGVTHLNISGLKMPRGIAVDWVAGNIYWTDSGRDVIEVAQMKGENRKTLISGMIDEPHAIVVDPLRGTMYWSDWGNHPKIETAAMDGTLRETLVQDNIQWPTGLAVDYHNERLYWADAKLSVIGSIRLNGTDPVVAIDNKKGLSHPFSIDIFEDYIYGVTYINNRIFKIHKFGHKSVTNLTSGLNHATDVVLYHQYKQPEVTNPCDRKKCEWLCLLSPSGPVCTCPNGKRLDNGTCVLIPSPTASAVVPTTDTCDLVCLNGGSCFLNARKQAKCRCQPRYNGERCQINQCSDYCQNGGLCTASPSGMPTCRCPTGFTGSRCDQQVCTNYCHNNGSCTVNQGNQPNCRCPPTFIGDRCQYQQCFNYCENNGVCQMSRDGVKQCRCPPQFEGAQCQDNKCSRCQEGKCNINRQSGDVSCICPDGKIAPSCLTCDSYCLNGGTCSISDKTQLPECLCPLEVTGMRCEEFIVGEQQSGRTASIVIPILLLLLLLAVVAFAWYKWRIKGAKGFQHQRMTNGAMNVEIGNPTYKMYEGEPDDDVGELLDADFALDPDKPTNFTNPVYATLYMGAHSSRNSLASTDEKRELLARGADDDLTDPLA
What is the function of this protein?
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells.  Involved in cellular lipid homeostasis.  Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors.  Acts as an alpha-2-macroglobulin receptor.
What are the official names of this protein?
Low-density lipoprotein receptor-related protein 1, LRP-1, Alpha-2-macroglobulin receptor, A2MR.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein. Membrane, coated pit.