PharMolix/UniProtQA huggingface dataset:
Protein: RL9_NITHX
Sequence: MEVILLERVAKLGQMGDVVKVKHGFARNFLLKRGKALRATAENRTKYDGMKAELEINNIKAKGEAAKVAEKIDGRDIVIIRQASETGQLFGSVTVRDIVAALAEDGITVSRPQVWLDAPIKTIGQQKLTVAVHPEVEAHVMVTVARSADEAERIKRGEDISTRREDRDAAAEAIAAAGEFFDPEAEPDDVAEAGGEQTAEEK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: ACTP_YERPP
Sequence: MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRSRQDYYTAGGRITGFQNGLAIAGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFSEAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANERDELRVSKITVIILGIVAIGLGILFENQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMILGPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQTGLGASKGGAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CASP4_SORBI
Sequence: MTKDVVIEHGESSKAPLVPAPVAAGVGRAVSIADVFLRFLSIVATIASAISMGTTNETLPFFTQFIQFEAKYSDLPSFTFFVAANAVVCTYLVLSIPLSIVHIIRPRARYSRLILVFFDAVMLALLTAGASAAAAIVYLAHKGNVRANWFAICQQFDSFCERISGSLIGSFAAMVLLIVLIFLSAFALARRH
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 4, SbCASP4.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: Y2456_MYCTU
Sequence: MSGTVVAVPPRVARALDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTTAKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFFARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHDLARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNRDEGTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLVGVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVAGYDAAFMSLGALAGAGFLLYLVAMPETVDSDVRVRSRPTLGGK
What are the official names of this protein?
Uncharacterized MFS-type transporter Rv2456c.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXK_VESOH
Sequence: MDLNTRGIINYLLLPISGIFYLASVLRKWLYQVNFFKVKKFKCPVIVVGNITVGGTGKTPIVILLAQYFKQQGKQVGVVLRGYGGMHHKGSLLVSKNTNVYLSGDEPLLIALQADLPVMVNRNRAQAVEDLINQCQVNLIISDDGLQHYRMDRNIEIAVIDGTRRFGNEFFLPSGPLRESIDRLKSVDFVINNAGFRAGEFNIKLILKVFVNVKTGEEKPLDYFNGEYCHGVAGIGYPQRFFDTLIRLGINLKPHIFADHYVYQQSDLVFEDNYPILMTAKDCVKCIQFANNQMWYLQVEANLSDNFFKELEAKL
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: Y421_DEHMB
Sequence: MSGHSKWATIKHAKGAADAKRGQLFTKLSREIIFAAKQGGPSPEGNARLRLAIQKAKDSRMPSDNIERAIKKGSGELEGTTVIEMILEGYGPGGVAVLVNGMSDNRNRTVSDVRHMFSKGGGSLAESGAVSWIFEAKGVIGVETARLDTDELSLKAIDMGAEDVNTDEGYMEIYTAMPDMEKIRQQLETQGVTIDSAEINMVPKNTVKLDEETAMQVLKLLDKLEELDDVQTVSSNADFDPEVVEKYHSQA
What are the official names of this protein?
Probable transcriptional regulatory protein DehaBAV1_0421.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LERL1_RAT
Sequence: MAGIKALISLSFGGAIGLMFLMLGCALPIYNQYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGVVVSAFGLPVVFARAHLIEWGACALVLTGNTVIFATILGFFLVFGSNDDFSWQQW
What is the function of this protein?
Negatively regulates growth hormone (GH) receptor cell surface expression in liver.  May play a role in liver resistance to GH during periods of reduced nutrient availability (By similarity).
What are the official names of this protein?
Leptin receptor overlapping transcript-like 1, Endospanin-2.
What is the protein family that this protein belongs to?
Belongs to the OB-RGRP/VPS55 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL11_LEGPH
Sequence: MAKKVEAYIKLQIPAGKANPSPPVGPALGQRGVNIMEFCKAFNAATQQMEQGLPIPVVITVYSDRSFTFITKTPPASVLLKKAAGIQSGSGTPNTKKVAKLNVSQLEEIAKVKKPDLTAADLAAAVRSIAGTARSMGIEVEGLE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: BBS10_HUMAN
Sequence: MLSSMAAAGSVKAALQVAEVLEAIVSCCVGPEGRQVLCTKPTGEVLLSRNGGRLLEALHLEHPIARMIVDCVSSHLKKTGDGAKTFIIFLCHLLRGLHAITDREKDPLMCENIQTHGRHWKNCSRWKFISQALLTFQTQILDGIMDQYLSRHFLSIFSSAKERTLCRSSLELLLEAYFCGRVGRNNHKFISQLMCDYFFKCMTCKSGIGVFELVDDHFVELNVGVTGLPVSDSRIIAGLVLQKDFSVYRPADGDMRMVIVTETIQPLFSTSGSEFILNSEAQFQTSQFWIMEKTKAIMKHLHSQNVKLLISSVKQPDLVSYYAGVNGISVVECLSSEEVSLIRRIIGLSPFVPPQAFSQCEIPNTALVKFCKPLILRSKRYVHLGLISTCAFIPHSIVLCGPVHGLIEQHEDALHGALKMLRQLFKDLDLNYMTQTNDQNGTSSLFIYKNSGESYQAPDPGNGSIQRPYQDTVAENKDALEKTQTYLKVHSNLVIPDVELETYIPYSTPTLTPTDTFQTVETLTCLSLERNRLTDYYEPLLKNNSTAYSTRGNRIEISYENLQVTNITRKGSMLPVSCKLPNMGTSQSYLSSSMPAGCVLPVGGNFEILLHYYLLNYAKKCHQSEETMVSMIIANALLGIPKVLYKSKTGKYSFPHTYIRAVHALQTNQPLVSSQTGLESVMGKYQLLTSVLQCLTKILTIDMVITVKRHPQKVHNQDSEDEL
What is the function of this protein?
Probable molecular chaperone that assists the folding of proteins upon ATP hydrolysis (PubMed:20080638).  Plays a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638).  Involved in adipogenic differentiation (PubMed:19190184).
What are the official names of this protein?
Bardet-Biedl syndrome 10 protein.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cell projection, cilium. Note=Located within the basal body of the primary cilium of differentiating preadipocytes.
Protein: MMPS3_MYCTU
Sequence: MSGPNPPGREPDEPESEPVSDTGDERASGNHLPPVAGGGDKLPSDQTGETDAYSRAYSAPESEHVTGGPYVPADLRLYDYDDYEESSDLDDELAAPRWPWVVGVAAIIAAVALVVSVSLLVTRPHTSKLATGDTTSSAPPVQDEITTTKPAPPPPPPAPPPTTEIPTATETQTVTVTPPPPPPPATTTAPPPATTTTAAAPPPTTTTPTGPRQVTYSVTGTKAPGDIISVTYVDAAGRRRTQHNVYIPWSMTVTPISQSDVGSVEASSLFRVSKLNCSITTSDGTVLSSNSNDGPQTSC
What are the official names of this protein?
Probable transport accessory protein MmpS3.
What is the protein family that this protein belongs to?
Belongs to the MmpS family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: SLYX_SHEPW
Sequence: MDNIEHRVEELEMKLAFQDGTIEELNQQVIKLNDVVALQQEQLRLLLNKLQSVEPSNMASQADETPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: RS7_SHISS
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: BIOB_METM5
Sequence: MKEIKLNSDSLEIYEKSASKKLNRNDLIDLWNLDLNDLLDISYALKKLFNKDKIDLCSIMNAKSGICPENCIFCSQSKHNSSKIDTYELKSKEEILKNAKSVEKYSNRFSIVVSGKTVTDLEFEKIIESIEEIQNKTKLKVCVSLGLLNKDQLKALNEKNVRIHNNLETSENYFKNICTTHDYNDKIKVILEAKKIGLEMCSGGIFGMGESIDDRINLFLDLKKLGVDSIALNLLNPIYGTKIYDRINSGDISPINSIGALKSLCIARITLPNKVIRLCGGREHVLKDMQKYSLLAIDGLMIGNYLTTNGQNIQSDLKMIEEMGFER
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: LEUC_NOSP7
Sequence: MSKGTLFDKVWDLHTVGTLPSGLTQLFIGLHLIHEVTSPQAFAMLRERGLKVLFPERTVATVDHIVPTENQARPFVDSLAEEMIQALENNCQENNITFYNIGSGSQGIVHVIAPELGLTQPGMTIACGDSHTSSHGAFGAIAFGIGTSQVRDVLASQTLALSKLKVRKIEVNGNLNPGVYAKDVILHIIRTLGVKGGVGYGYEFAGTTFEQMNMEERMTVCNMAIEGGARCGYVNPDRVTYDYLKGRDFAPKGADWDKAVAWWDSIKSDVDAQYDDVVVFDAAEISPTVTWGITPGQGIGVNQSVPQPEELLEEDRFIAEEAYRYMDLYPGQPIKGTKIDVCFIGSCTNGRISDLREAAKIAKGRHVAEGIKAFVVPGSERVKQEAETEGLDKIFQEAGFEWREPGCSMCLAMNPDKLQGRQISASSSNRNFKGRQGSSSGRTLLMSPAMVATAAIKGEVSDVRELL
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: SCRB_BACSU
Sequence: MTAHDQELRRRAYEEVEKKEPIANSDPHRQHFHIMPPVGLLNDPNGVIYWKGSYHVFFQWQPFQTGHGAKFWGHYTTQDVVNWKREEIALAPSDWFDKNGCYSGSAVTKDDRLYLFYTGNVRDQDGNRETYQCLAVSDDGLSFEKKGVVARLPEGYTAHFRDPKVWEHEGTWYMVIGAQTENLKGQAVLFASDNLTEWRFLGPITGAGFNGLDDFGYMWECPDLFSLQGSDVLIVSPQGLEADGFRYQNVYQSGYFVGRLDYNKPELKHGEFTELDQGFDFYAPQTLEDDQGRRILFAWMAVPDQDEGSHPTIDCHWIHCMTLPRQLTLSGQKLIQQPLPELKAMRRNEKKIHINMHGSSGALPVEKPERTEILLEDIHTESGFSISIRGTATFSFHKDEGIVTLERKSFDGKRTEARHCRIKDLHTVHMFLDASSVEIFINNGEEVLSARYFPFPGNHEVTASATGKSEMNVGIWTLM
What are the official names of this protein?
Sucrose-6-phosphate hydrolase, Sucrase, Invertase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: MFR2_PHOSM
Sequence: MATATTTLHSTTGTVYVADGTTDGKVGYYNHTDDSTNVIRKPIPIEVEDARTLSKSPTTKAEGYQLVNFHTKIPEEHFLNSKLPENKELIEEVYFDECRRLVQEVTGAAEAYPYVYRVRNQEQNAKESNKSNFHTDFVPIVHVDRDDVTAPQRLRASLGAEKADMLLSKYKSYGSINVWRPVKNMVQKWPLMLVDHKSIEDWDYSTHMFTLHSSNDERVATRGAKEHETILTHDKRYRYIYASDMTPEEAWLFFAFHSDPALGIPHGAFWDDSTKEEALTRCSIEVRIWVFFD
What is the function of this protein?
Oxidoreductase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) (PubMed:27056201).  SQS1 is composed of a 2,8-dioxobicyclic[3. 2. 1]octane-3,4,5-tricarboxyclic acid core that is connected to two lipophilic polyketide arms (PubMed:27056201).  These initial steps feature the priming of an unusual benzoic acid starter unit onto the highly reducing polyketide synthase pks2, followed by oxaloacetate extension and product release to generate a tricarboxylic acid containing product (By similarity).  The phenylalanine ammonia lyase (PAL) M7 and the acyl-CoA ligase M9 are involved in transforming phenylalanine into benzoyl-CoA (By similarity).  The citrate synthase-like protein R3 is involved in connecting the C-alpha-carbons of the hexaketide chain and oxaloacetate to afford the tricarboxylic acid unit (By similarity).  The potential hydrolytic enzymes, M8 and M10, are in close proximity to pks2 and may participate in product release (By similarity).  On the other side, the tetraketide arm is synthesized by a the squalestatin tetraketide synthase pks1 and enzymatically esterified to the core in the last biosynthetic step, by the acetyltransferase M4 (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The biosynthesis of the tetraketide must involve 3 rounds of chain extension (PubMed:11251290, PubMed:15489970, PubMed:28106181).  After the first and second rounds methyl-transfer occurs, and in all rounds of extension the ketoreductase and dehydratase are active (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The enoyl reductase and C-MeT of pks1 are not active in the final round of extension (PubMed:11251290, PubMed:15489970, PubMed:28106181).  The acetyltransferase M4 appears to have a broad substrate selectivity for its acyl CoA substrate, allowing the in vitro synthesis of novel squalestatins (Probable).  The biosynthesis of SQS1 requires several oxidative steps likely performed by oxidoreductases M1, R1 and R2 (Probable).  Finally, in support of the identification of the cluster as being responsible for SQS1 production, the cluster contains a gene encoding a putative squalene synthase (SS) R6, suggesting a likely mechanism for self-resistance (Probable).
What are the official names of this protein?
Oxidoreductase R2, Squalestatin S1 biosynthesis cluster protein R2.
What is the protein family that this protein belongs to?
Belongs to the asaB hydroxylase/desaturase family.
Protein: RS19_THEVO
Sequence: MVVNKQGSVKSIKRKARKSRKVTTGRAKEFSYKGYTLEQLQEMSLEELIKILPARARRSLSREMNHDQKKLVEKLEGDYDDIKTHVRDVIILPSYVGKIVEVYNGNSYSKFEIKPEMIGHYLGEFVMTRKEVKHSGPGVGATRSSKFMPLK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: Y2154_ALIF1
Sequence: MDYEFKKNTLEGTYHANFSMGHEAMGRWLVEDVAKNTDLLAEIYKHIALIKNTQDEWTLSGKVMTLVLSDQEVIVQENALFEQSDEEFEEDIHMYDDECISVCGLEDFETMLQSWEAFINRF
What are the official names of this protein?
UPF0231 protein VF_2154.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: YELA_DICDI
Sequence: MSQSDPLNVVSRILNKISKDNFQVLIDQLVSKCQLLDKNESTLFINNIFEKVVEEPSSSSYYIQIINKIQPIFQQNFSIGVGNKLVENFNKRYQILTDQINSNEETFDFNSSKQSFLNLCKFMGECYYTLPSSFLVDVVNNHLPQVTKETADDMTLQQLMEIEIIATSFTSAGKTIESMGGFSSKHENNKTHNNNNNNNNHDHDDDDHDEEDNENNYENTTSTTNNINNNNIQSRENDLHFKGIQKALEDATSVLSFLIENRQLLPPRVRFMVKNLFELKNNKWIIPKAINDDLNAQREVVKVATNHGKTISKSLSEKCDDDSTLNTIFWKSFFQALGIQNYKILRQLMLDDKSNISPSSTSPTIPLSPFLRRSMNITSPSQFNLNNCNNNNNSININNNNMDIDASFDLNDGLMESSSNNNNSNSQLQFSLSSSSGIKDNHNVPTIDLNTISSNNNQQINLPSGFLSPKVARSNSPSLSSVVKQPQSQQNNNNNNNNNNNNTTITTTTSSNNNINNNNNNNNNNKIKESPELSSAPDSNLSVIVSIIDSKIWTPQKEIWKKKIMNKIIPMKSILKKPQKIEILAAIWQNMCDNNYEYGSYLDLCLNLIKMDEGDISPLYSLDGGNVPPVKPYQQSAQPPPPPPSSSSSSAQQPPNEPVNPLLNKLKGPNRRSSMATLQMKPSGISEARRSSISVPFELNRRGSLSGDIPSYCPPAPKLKSTPTLKSTPAIVQNGGSITSTSSSSSSSSSSSSSTTKNIHPTSESKKQPIAKKHKPDLDSFKDVLISSLQDDFALKMFVKKRSLTTYMELLKDLYREFIIEIPLLLKCISLVHNGLYELTDEECTMLFDLEEMAQEQQNLEKQNDQQQNLLTQNNQIFQWKTNTWEEKPQTPPPPPTSYFDLGSDVFVL
What is the function of this protein?
Plays as essential role in regulating terminal differentiation.
What are the official names of this protein?
Yellow mounds protein A, YELA.
Protein: VL1_HPV6B
Sequence: MWRPSDSTVYVPPPNPVSKVVATDAYVTRTNIFYHASSSRLLAVGHPYFSIKRANKTVVPKVSGYQYRVFKVVLPDPNKFALPDSSLFDPTTQRLVWACTGLEVGRGQPLGVGVSGHPFLNKYDDVENSGSGGNPGQDNRVNVGMDYKQTQLCMVGCAPPLGEHWGKGKQCTNTPVQAGDCPPLELITSVIQDGDMVDTGFGAMNFADLQTNKSDVPIDICGTTCKYPDYLQMAADPYGDRLFFFLRKEQMFARHFFNRAGEVGEPVPDTLIIKGSGNRTSVGSSIYVNTPSGSLVSSEAQLFNKPYWLQKAQGHNNGICWGNQLFVTVVDTTRSTNMTLCASVTTSSTYTNSDYKEYMRHVEEYDLQFIFQLCSITLSAEVMAYIHTMNPSVLEDWNFGLSPPPNGTLEDTYRYVQSQAITCQKPTPEKEKPDPYKNLSFWEVNLKEKFSSELDQYPLGRKFLLQSGYRGRSSIRTGVKRPAVSKASAAPKRKRAKTKR
What is the function of this protein?
Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter.  The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins.  Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment.  This binding mediates a conformational change in the virus capsid that facilitates efficient infection.  The virion enters the host cell via endocytosis.  During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus.  The virion assembly takes place within the cell nucleus.  Encapsulates the genomic DNA together with protein L2.
What are the official names of this protein?
Major capsid protein L1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae L1 protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: YJGA_ECOLI
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEG
What are the official names of this protein?
UPF0307 protein YjgA, x96 protein.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Has been seen to comigrate with the 50S ribosomal subunit in sucrose gradients.
Protein: RL17_EXIS2
Sequence: MAYSKLGRTSSQRKALLRDLATDLIINERIQTTEQKAKELRPVVEKLITLGKRGDLHARRQVASFVRREAAGQNEAGKTQDAIQKLFADVAPRFAERQGGYTRIMKMGPRRGDGAEMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: HEM6_RICFE
Sequence: MKIENKEIASNWFTDLRDLLCKEFEKIEEEYAQTKGLKPAKFVRTSWQRNGGGGGIMSLMKGEVFEKVGVNISTVFGEFSPEFRSEIPGAELDGKFFATGISLVAHLKSPLIPAMHFNTRYIETSKSWFGGGGDLTPFYPKENETAKFHAAFKEACDKYDSSYYPKFKKQCDEYFYLKHRKEPRGVGGIFYDYLNSGNFEQDFAFTQDVGRALLSVYPEIVRSKLFLPWTTEQKEYQLIRRGRYVEFNLLYDRGTKFGLMTDGNVEAILMSLPPEVKFN
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2_ONYPE
Sequence: MTLNKKTNNENSSKTTPKLSKETDLRNDFASKNYVFNPQDKVFQIAQVFGITSAVLIKKLLQLGLKADVNQTLEKDIVELLAKDYNIQVSEPQEKHTPPQLQPQTPSLTKTKPNQKLNLQKKSPIVTIMGHVDHGKTTLLDAIRKTRVVDQEFGGITQHIGAYQVEYQGNKITFIDTPGHEAFDKMRARGAKITDICILVVAVDDCVKPQTLEALKHAQKAQIPIIVALNKIDKPNNNTQQIMQELSSYDLLPEEWGGTTPYIAISALKREGLEKILEIILLVSEIQNLQANPDQKAQGTVIEASLDKSLGLVATFIVSDGNLKVGDIVVAGASYGKIRSMEDENKKKLTKALPSQPVRVAGLKEVPQAGDIFYAVANEKQARQIVAEKKSQTKENLAKTLSPLNLEDILQDLETEKPQELNIILKADTQGSLEALQGMIAKIKVSDLKVQLLRAAVGTITETDIAFAKSSDSLLIGFNIKPASSTLKSAQRQEVKITIHNVIYRIIEDIEQKLKSMIKPTFEEVVTGKVEVRKIFNISKVGNIAGCYVTQGIVNNSDFAKVMRNDEVLFKGKIASLKHLKDNIKSAKQGYECGILLDGFNDFEINDIIETSKLSKVEE
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_TOBSV
Sequence: MDLVIKNLIVYHLRRRIDIGTSFGIEPADYIDWVKVFLLKFIIEHTARFADFATIHTTMLLVLGEDDPNYVEKDTPIMEIDPFYLPYDDLDVDYTSLRVCGDEDQSCSDRDELSDFISNISHIPEGTSWGSESDTSFVEHLETIQDIPTKCEIADKPVEEIPFDDDGKVVNDVWVDAELSNAPEISCDADIRACGFVSLRLLESSRGYPKWTPERVSSGLNPDLPVNSKPAVDEIFPHHHSVDDRFFQEWVETHDIDLEVTSCDLDMSTFNDWTKGVDTRLVPNMSVGGLSHRVPTQREALLAIKKRNMNVPELQSNFDHDDVLNRCVTRFITHVVDKTRLSKLNPISGEELHYFNQYLENKNPPLSEYKGPVPLVALDKYMHMIKTTLKPVEEDNLHIERPIPATITYHKKGVVMMTSPYFLCAMVRLLYVLKSKFVVPTGKYHQIFQMNPELLKHSKEFKEIDFSKFDKSQGRLHHDVQFRLFLALGIPEHFVTTWFNSHEKSYIRDRDCGIGFSVDYQRRTGDACTYLGNTLVTLSVLSYVYDLSNPNILFVAASGDDSLIGSIEPLPREKEDLCVSLFNFETKFPHNQPFICSKFLLVVECDDGSEEVLAVPNPLKLLQKLGPKNLQVTVLDDYYQSLCDILWVFNDADVCRRTAELAEYRRFKGTKKCLFLESALLSLPSLVANRMKFVRRTINLESSRACIRNDVYSDLVPHFDSRVSRCDDSDGVRTSTFDDRKSSKHASDKLRKTECYGEARCRIKPRRNRKSESGAVQYSQSSGIETGKANSSRKGRIKLH
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 3 RNA segments, RNA1, RNA2 and RNA3.
What are the official names of this protein?
RNA-directed RNA polymerase 2a, 2a pol, 2a polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: ERPA_SALEP
Sequence: MSDDVALPLQFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: UVRB_RHILO
Sequence: MVSDFEPAGDQPTAIKDLVEGVDNNDRTQVLLGVTGSGKTFTMAKVIEETQRPALILAPNKTLAAQLYSEFKKFFPDNAVEYFVSYYDYYQPEAYVPRTDTFIEKESSINEQIDRMRHSATRSLLERDDVIIVASVSCIYGIGSVETYTAMTFQMQIGDRLDQRALLADLVAQQYKRQDINFVRGSFRVRGDTIEIFPAHLEDRAWRISMFGDEIEQITEFDPLTGQKTGELKSVKIYANSHYVTPRPTLNQAIKSIKEELKQRLVELERAGRLLEAQRLEQRTRFDLEMLEATGSCAGIENYSRYLTGRQPGDPPPTLFEYIPDNALVFIDESHVTVPQIGGMYRGDFRRKATLAEYGFRLPSCMDNRPLRFEEWDAMRPLSVAVSATPGGWEMEQSGGVFAEQVIRPTGLIDPPVEVRPAKSQVDDVVGEIRETTKAGYRTLVTVLTKRMAEDLTEYLHEQGVRVRYMHSDIDTLERIEILRDLRLGAFDVLVGINLLREGLDIPECGFVAILDADKEGFLRSETSLIQTIGRAARNVDGKVILYADQVTGSMERAMAETNRRREKQMEWNAANGITPESVKSRISDILDSVYEKDHVRADISQFTDSAGAMMGNNLKAHLDAMEKQMRDAAANLDFEKAARIRDEIKRLREMELSISEDPLAKYADMESPVSGREKGKHNKGVAKHRTAEEQERFRKLDEARAAEEAARAARPNLFRKPALDEMGADGAVPAKKPLFAKPSIDDMGPGTDMPTPAGAVSRSLFKKQSASEAHGSDFGIPGEPVRPLFKKNSLDEMTVRRTEKPVEGKVPAKPQPISHPVGAGRTDVKDRDDSAKPIVRQRAGIGSYEDPGDARREKRRPGKTGRPGK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.