PharMolix/UniProtQA huggingface dataset:
Protein: RNZ_STAA1
Sequence: MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQILIQNEDTPNFNFVKDFDSFKV
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: MURC_STRS2
Sequence: MTKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGLEQAGIQILPFDEKNITADVELIAGNAFRPDNNVEIAYADAQGYTYKRYHEFLGEFMKGFTSLGVAGAHGKTSTTGLLAHVMRNITDTSFLIGDGTGRGSANAQYFVFESDEYERHFAPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQVKNALFVFGEDEQLRRITANAPIYYYGLEDNNDFVAYDLKPSTSGSQFKVRHGEEELGEFQIPTFGKHNVMNATAVIANLYIAGFDLQLVAEHLKTFGGVKRRFTEKIVNDTVIIDDFAHHPTEIIATIDAARQKYPSKELVAIFQPHTFTRTIALLDEFADALNGADAVYLAQIYGSARETDNGQVKVEDLAAKINKKGGLVTVENTSPLLDHDNAVYVFMGAGDIQSYEYSFERLLSNLTNNVQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_STRR6
Sequence: MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQPEKTVTVVGHKAELVEEVLAEQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGDTPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATDFEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLKDFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEANVILKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPNSSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKYKTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYATRLPHHPKNQ
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_BRADU
Sequence: MTTRIDIRFAELAKQGRSAFVTFLMAGDPDPATSLEIIKALPKSGADVIEIGMPFTDPMADGPSIQAAGLRALKAGMTLKKTLELVRGFRKDDNATPIVLMGYYNPIYIYGVDKFLVDAKSAGVDGLIIVDLPPEEDDELCLPAMKAGLNFIRLATPTTDDKRLPAVLANTSGFVYYVSITGITGAAAADSSAVSEAVARIKRHTKLPVCVGFGIRTPETARAIASHANGAVVGTALVDALKNSLDADGRATAKTVNAVAELTASLAQGVKGAQQAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: DDL_ANADE
Sequence: MSTWTGKRVAVLYGGRSSEREVSLRTGAACAEALRQKGHDVVLVDVDLEVAARLRAERVEVAFVALHGRWGEDGSIQGLLESMAIPYTGSGVLASAMGMDKTVSKAIFRSLGLAVADYRVFPRAAAGAIGVDDLPFGLPCVVKPAGEGSSVGVHLVNAAAELGPACRDAAGYAGDVIVERYVKGTEVDVAVLEGKALGAIEIVPANAFYDYAAKYTAGTTKYFYPARIPEAHVRAVMEAAEAAHRGIGCSGVTRVDFIVAADGTPYILEVNTLPGMTATSLVPKIAAGLGLSFPDLCDRILDGAALKA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KMO_ASPTN
Sequence: MAQSTKQKVVIVGAGPVGSLAALYAAARGDEVEVYELRGDLRDPSTIPLNFTKSINLALSERGINAMRHSNREEMIHKVLEEAIPMHGRMIHGRDDGKLWEAAQAYDVHGRYINAADRSTLNNALLDELERTPNVNLFFNHKLTGADFRANKAWFERRIPGESTSDRVEIQVNFDYLIGADGAHSASRYHMMKYARVDYQQEYIDTLWCEFRIPPTDDGDFRISPNHLHIWPGKEFMFIALPSADKSFTCTLFAPAGHYARLKSSPQNLLESFDTHFPGVCPELITPKDLQEQFETNPHLPLISIKCKPHHFDSSVVIVGDAAHAVLPFYGQGLNAGLEDIRVLFEIMDKHGVYNPDISPEMRTLSRQAAFQAYTDQRIADAHAINDLSKQNYLEMRWGVKLPLYKLRKSIEETLDRYVPSLGWQTQYARVSFSNQRYSEVIKAVRRQGRLLGFGFISAIVSGVAVVGILAWKRPREASVLSVLKSSARQLGDVWRSKFR
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Biosynthesis of nicotinic acid protein 4, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: TRMN6_SHEFN
Sequence: MSFTFKQFHIDDQQCGMAVSTDAVLLGAWAELTQSSHILDIGAGSGLLSLMAAQRSPHHTSIIAVEIDNAAAKACQFNIKQSPWSETVQLFHGAIQDFQQRHNNNDEPLFDHIICNPPYFEQGTQAKNSARADARHTNTLSFAELQNVISQLLAPQGTASVILPLQSLASFIQQLNAYGLFVAKQLDIISIEGKVANRSILAIQHNPTTAEPQTLTNPAVETQYHQMTIRDKQGRYSETMIDLCRPFYLKL
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERC_NIACI
Sequence: MSKRAYNFNAGPAALPLEVLERAQAEFVDYQHTGMSIMEMSHRGAVYEAVHNEAQARLLALLGNPTGYKVLFIQGGASTQFAMIPMNFLKEGQTANYVMTGSWASKALKEAKLIGDTHVAASSEASNYMTLPKLQEIQLQDNAAYLHLTSNETIEGAQFKAFPDTGSVPLIGDMSSDILSRPFDLNQFGLVYAGAQKNLGPSGVTVVIVREDLVAESPKHLPTMLRYDTYVKNNSLYNTPPSFGIYMVNEVLKWIEERGGLEGVQQANRKKASLIYDAIDQSGGFYRGCVDVDSRSDMNITFRLASEELEKEFVKASEQEGFVGLKGHRSVGGLRASIYNAVPYESCEALVQFMEHFKRSRG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCR_HALS3
Sequence: MDPEAANNGEPRRITSVLNAVEIIDAIKEHRGITLQELTTELDLTKATIHTYMATLRQVGIVEQDGDGTYQLGDWFVPVSNYARNSTDLYRLGREEIDKLATQTRHTAHLVTESDGRQIVLYESMGEESVTTEYHLRMRETPRKLHTSAAGKSILAFLPEGRRETLISEIEFGTESSTPIGSPDALREQLATVRDQGYAINDEEEIHGIRSIGAPIRGRTEDVAGAVSVTAPKTRLQNAEFAGEVPALVMEAANIIEVRLETA
What is the function of this protein?
Probably regulates transcription of the arcABC operon.
What are the official names of this protein?
Probable HTH-type transcriptional regulator ArcR.
Protein: HIS6_CERS5
Sequence: MLKTRIIPCLDVADGRVVKGVNFVDLRDAGDPVEAARAYDAAGADELCFLDIHATHENRGTMYDLVTRTAEQCFMPLTVGGGVRTQQDVRALLLAGADKVSFNSAAVADPNVVAEAADRFGSQCIVVAIDAKTVAPGRWEIFTHGGRRATGIDAVEFAQDVAAKGAGEILLTSMDRDGTRSGFNLPLTRAISDAVRIPVIASGGVGTLDHLVEGVTEGGASAVLAASIFHFGEFTIGEAKAHMAAAGIPVRLA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2AZ_ASPCL
Sequence: MPGGKGKSVGGKAGSKDAAGKTQKSHSAKAGLQFPCGRVKRFLKNNTQNKMRVGAKAAVYVTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDEELDTLIRATIAFGGVLPRINRALLLKVEQKKKNKSEA
What is the function of this protein?
Variant histone H2A which can replace H2A in some nucleosomes.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activation signal is received.  Near telomeres, it may counteract gene silencing caused by the spread of heterochromatin proteins.  Required for the RNA polymerase II and spt15/TBP recruitment to the target genes.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
Histone H2A.Z.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: AMPA_SYNPW
Sequence: MKISLSPATPEAWSGSVLALGIPENDPQGLVAAMEQRFSLQLSDWLKQKPFSGKPGDCVSLPLLRSDCTALVLVGLGEASSVDRDRLRLAAAAAARAAQGQGGTLGLLLPWSSDTPEEDAAAAAEAVRLALYSDERFRSKPEPSPKPDQLELLGSLPGGLSHGLEAVHPVCAGVELARELVAAPPNSVTPAELARTASHLAHEHGLELTILERSDCEERGMGSFLSVCQGSDMDPKFIHLTYRPNDAASKRLVLVGKGLTFDSGGYNLKVGAAQIDMMKFDMGGSAAVFGAMRAIAELRPAGVEVHMLVASCENMINGSAVHPGDIVTASNGTTIEINNTDAEGRLTLADALVYACKLKPDAIVDLATLTGACVIALGDEIAGLWSGDDSLSSQLEMAAQAAGEGLWRMPLHSPYRKGLKSLLADMKNTGPRPGGSITAALFLKEFVDAGIPWAHIDIAGTVWSDKGRGLDPSGATGYGVRTLVNWITNQANT
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2364_STAAN
Sequence: MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTLYRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSNYEVMQVSLDYLLQFKIDNKALLQCIEAGNNKLRFYQSAFYQELFDFYYDLFKSDDDTYTKFKTDMLLQSLSTSVFAFQIEHRHISIEAYRNYLLNIYLDEVERND
What are the official names of this protein?
HTH-type transcriptional regulator SA2364.
Protein: NRFE_ECOLI
Sequence: MLTPLTAFAGVRLRWPAMMRLTCIGILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLWVLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEGRDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGACARICWRWALPGWSALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQRGIFCHWSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYGWRARDGGPAVHFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPYFNRATLPFGLLMLVVIVLATFVSGKRVQLPALVAHAGVLLFAAGVVVSSVSRQEISLNLQPGQQVTLAGYTFRFECLDLQAKGNYTSEKAIVALFDHQQRIGELTPERRFYEARRQQMMEPSIRWNGIHDWYAVMGEKTGPDRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWRGKKRDE
What is the function of this protein?
May be required for the biogenesis of c-type cytochromes.  Possible subunit of a heme lyase.
What are the official names of this protein?
Probable cytochrome c-type biogenesis protein NrfE.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROB_HELPH
Sequence: MQEILIPLKEKSYKVFLGELPKIELKQKALIISDSIVAGLHLSYLLKRLKALEVRVCVIESGEKYKNFHSLERILNNAFEMQLNRHSLMIALGGGVISDMVGFASSIYFRGIGFINIPTTLLAQVDASVGGKTGINTPYGKNLIGSFYQPKAVYMDLVFLKTLEKREFQAGVAEIIKMAVCFDKNLVETLETKDLKDCLEEVIFQSVNIKAQVVMQDEKEQNIRAGLNYGHTFGHAIEKETDYERFLHGEAIAIGMRMANDLALSLGMLTLKEYERIENLLKKFDLIFHYKITDIQKFYERLFLDKKSENKTIKFILPKGIGAFEIVSHIPKETILKVLEKWH
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB20_MYCTO
Sequence: MLVAYICHVKRLQIYIDEDVDRALAVEARRRRTSKAALIREYVAEHLRQPGPDPVDAFVGSFVGEADLSASVDDVVYGKHE
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Neutralizes the toxic effect of cognate toxin VapC20.
What are the official names of this protein?
Antitoxin VapB20.
Protein: RL22_FRATM
Sequence: MEVQAKLKFARISAQKCRLVADQIRGLPVEQAINLLTFSNKKAAVLIKGVLNSAVANAEHNDGMDVDSLVVSTIFVDEGPTMKRFEARAKGRGNRILKRTSHITVKVAEKK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DTXS3_METRA
Sequence: MAKVSLEKLLRIPPSLTQSISQTKVDYLNLGHSGLRVSRPILGGLHLGSRKWLPWVLDEEKALPILKAAYDLGVNTWDTANVYSNGESERIIAKALSKYKIPRNKVVLMTKCYRVMSDPERFDPGSGVTMHHELADYSKDYVNQWGLSRRALFSAVEASLDRLNTSYIDVLQIHRFDHTVPPEETMSALNDLIRAGMVRYIGASSMWTFQFATLQHIAETKGLTKFISMQNHYNLIYREEEREMNQYCKMTGVGLIPWGPLASGRLARRPTQEEGSLRASCSAHGSLYESDDYNVDRIIQRVAEIAEKRGWPMSHVSLAWLNRRVTAPIIGFGSVGRIEEALAARGKELSRDEEQYLEELYVPQRIQGHS
What is the function of this protein?
Aldo-keto reductase; part of the gene cluster that mediates the biosynthesis of destruxins, insecticidal cyclic hexadepsipeptides which induce flaccid paralysis and visceral muscle contraction in insects through targeting the calcium channels and vacuolar-type ATPases (PubMed:22232661).  The aldo-keto reductase dtxS3 converts alpha-ketoisocaproic acid from deaminated leucine into alpha-hydroxyisocaproic acid (HIC), which is the first substrate for destruxin assembly by dtxS1 (PubMed:22232661).  L-aspartate decarboxylase dtxS4 converts aspartic acid into beta-alanine, the last substrate for the destruxin assembly line performed by dtxS1 (PubMed:22232661).  The nonribosomal peptide synthetase dtxS1 synthesizes destruxins B and B2, whereas the cytochrome P450 monooxygenase dtxS2 is required to convert destruxin B into other destruxin derivatives, including destructins C, D, A and E (PubMed:22232661).  Destruxin E-diol (ED) is further produced in a non-enzymatic manner from destruxin E (PubMed:22232661).  Destruxins play an important role in virulence and escape from insect host immune defenses (PubMed:22232661).
What are the official names of this protein?
Aldo-keto reductase dtxS3, Destruxin synthesis protein 3.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: DAPB_ECO81
Sequence: MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUC_PSEE4
Sequence: MAGKTLYDKLWDAHEVKRRDDGSSLIYIDRHIIHEVTSPQAFEGLRLASRKPWRIDTNIATPDHNVPTTPERKGGIEAIVDQVSRLQVQTLDENCDEYGIVEFKMNDERQGIVHVISPEQGATLPGMTVVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQCLVAKKMKNMLVRVEGELPAGVTAKDIVLAVIGKIGTAGGNGHAMEFAGSAIRELSMEGRMTICNMSIEAGARVGLVAVDDTTVNYVEGRPYAPKGEQWKQAVASWKGLVSDADAVFDTLVELDAAQIKPQVSWGTSPEMVLAVDQCVPDPAAEADLIKRGSIERALKYMGLSANQAITDIKLDRVFIGSCTNSRIEDLRAAAEIAKGRKVAANVKQALVVPGSGLVKAQAEREGLDKIFLEAGFEWREPGCSMCLAMNPDRLESGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVTGHFIDVRELIQGSAA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CTR86_DEBHA
Sequence: MMEEELYKSVIVTAKSVRSVLLEETSNVEDCQKNLNALGQIVSASSQSQEYRSQILANNGLPDVLVEILNRSFQDNVPTEELKFTLYIRLMRGILLLARNLVITKQFVEFSSILSSLENFNQKVSHNNEFYSKTLVVYIQFLANMSQITREQNIVAEIVETFFKNEDLMSLIANDDQMKMPFAAFLKNILSNSDNLYDVLTHDDTILRYTISELDKADIHNEDLDQYSSLLILTFQNIIAHETYSKWLKRIDCESAEFSRIMKLNQVIVTSKEDWDNYQLTAMLAWIFDNFLVFSEISKSILLSSIYDPLELKRVHLNLIILLDCLSDLGKFEATKQFLEHYNAIEELISLLRVVHESVDRKTLKNKEKIEETVGKKEFPQVKSLIIEVIAFLVHGSFEIQEKMRELHGLELVLSNCMIDDNDPFIKERAIVCVKFLLANNEKNQQFVADLEAKQTVDDDALKEVGYEVQIEDGNVKLRKTENQKLQEI
What is the function of this protein?
Essential protein which may be involved in threonine biosynthesis.
What are the official names of this protein?
Copper transport protein 86.
What is the protein family that this protein belongs to?
Belongs to the CTR86 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_ECO57
Sequence: MGLSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YRPG_BACSU
Sequence: MEYTYLGRTGLRVSRLCLGTMNFGVDTDEKTAFRIMDEALDNGIQFFDTANIYGWGKNAGLTESIIGKWFAQGGQRREKVVLATKVYEPISDPNDGPNDMRGLSLYKIRRHLEGSLKRLQTDHIELYQMHHIDRRTPWDEIWEAFETQVRSGKVDYIGSSNFAGWHLVKAQAEAEKRRFMGLVTEQHKYSLLERTAEMEVLPAARDLGLGVVAWSPLAGGLLGGKALKSNAGTRTAKRADLIEKHRLQLEKFSDLCKELGEKEANVALAWVLANPVLTAPIIGPRTVEQLRDTIKAVEISLDKEILRMLNDIFPGPGGETPEAYAW
What are the official names of this protein?
Uncharacterized oxidoreductase YrpG.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: YCF3_LOTJA
Sequence: MPRSRINGNFIDKTFSVVANILLQIIPTTSGEKEAFTYYRDGMSAQSEGNYAEALQNYYEAMRLEVDPYDRSYILYNIGLIHTSNGEHTKALEYYFRALERNPFLPQAFNNMAVICHYRGEQAIRQGDSEIAESWFDQAAEYWKQAIALTPGNYIEAQNWLKITRRFE
What is the function of this protein?
Essential for the assembly of the photosystem I (PSI) complex.  May act as a chaperone-like factor to guide the assembly of the PSI subunits.
What are the official names of this protein?
Photosystem I assembly protein Ycf3.
What is the protein family that this protein belongs to?
Belongs to the Ycf3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: UREG_MYCTO
Sequence: MATHSHPHSHTVPARPRRVRKPGEPLRIGVGGPVGSGKTALVAALCRQLRGELSLAVLTNDIYTTEDADFLRTHAVLPDDRIAAVQTGGCPHTAIRDDITANLDAIDELMAAHDALDLILVESGGDNLTATFSSGLVDAQIFVIDVAGGDKVPRKGGPGVTYSDLLVVNKTDLAALVGADLAVMARDADAVRDGRPTVLQSLTEDPAASDVVAWVRSQLAADGV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP9_YEAST
Sequence: MSYEKKSVEGAYIDDSTTFEAFHLDSRLLQAIKNIGFQYPTLIQSHAIPLALQQKRDIIAKAATGSGKTLAYLIPVIETILEYKKTIDNGEENGTLGIILVPTRELAQQVYNVLEKLVLYCSKDIRTLNISSDMSDSVLSTLLMDQPEIIVGTPGKLLDLLQTKINSISLNELKFLVVDEVDLVLTFGYQDDLNKIGEYLPLKKNLQTFLMSATLNDDIQALKQKFCRSPAILKFNDEEINKNQNKLLQYYVKVSEFDKFLLCYVIFKLNLIKGKTLIFVNNIDRGYRLKLVMEQFGIKSCILNSELPVNSRQHIVDQFNKNVYQLLIATDDTEYIKEEDDEIEEGHNTENQEEKSLEGEPENDKKPSKKKKVQVKKDKEYGVSRGVDFKNVACVLNFDLPTTAKSYVHRVGRTARGGKTGTAISFVVPLKEFGKHKPSMLQTAKKDERILSRIIKQQSKLGLELQPYKFDQKQVEAFRYRMEDGFRAVTQVAIREARVKELKQELLASEKLKRHFEENPKELQSLRHDKELHPARVQQHLKRVPDYLLPESARGNGTKVKFVPFHNAKKRHSHKKGRVSKPKNGKVDPLKNFK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP9, DEAD box protein 9.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX56/DBP9 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RS17_HALS3
Sequence: MAIGLNVTEPEGTCSDEDCPFHGNLSVRGQVLEGEVASTDMEKTVVVEREYDVFVPKYDRYMKRRSRVPAHAPECFDISVGDTVSIAETRPLSKTKSHVVVEITDGGDA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RF1_ECOK1
Sequence: MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTLA_LACLL
Sequence: MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVVEAGSCIAEAHSSQTGMLAREASGEELPYSVTMMHGQDHLMTTILLKDVIHHLIELYKRGAK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIIA component, EIIA-Lac, EIII-Lac, Lactose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HLPDA_HUMAN
Sequence: MKHVLNLYLLGVVLTLLSIFVRVMESLEGLLESPSPGTSWTTRSQLANTEPTKGLPDHPSRSM
What is the function of this protein?
Increases intracellular lipid accumulation.  Stimulates expression of cytokines including IL6, MIF and VEGFA.  Enhances cell growth and proliferation.
What are the official names of this protein?
Hypoxia-inducible lipid droplet-associated protein, Hypoxia-inducible gene 2 protein.
What are the subcellular locations of this protein?
Lipid droplet. Secreted. Membrane; Single-pass membrane protein.