PharMolix/UniProtQA huggingface dataset:
Protein: CALCB_MOUSE
Sequence: MDFWKFFPFLALSTIWVLCLASSLQAAPFRSALESSLDLGTLGDQEKHLLLAALMQDYEQMKARKLEQEEQETKGSRVTAQKRSCNTATCVTHRLADLLSRSGGVLKDNFVPTDVGSEAFGRRRRRDLQA
What is the function of this protein?
CGRP induces vasodilation.  It dilates a variety of vessels including the coronary, cerebral and systemic vasculature.  Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (By similarity).
What are the official names of this protein?
Calcitonin gene-related peptide 2, Beta-type CGRP, Calcitonin gene-related peptide II, CGRP-II.
What is the protein family that this protein belongs to?
Belongs to the calcitonin family.
What are the subcellular locations of this protein?
Secreted.
Protein: OGT_SALTI
Sequence: MLRLLEEKIATPLGPLWVVCDEQFRLRAIEWEQYRDRMEQLLNIHYRHEGYERVSATNPGGLSDKLADYFAGNLAVIDTLETATGGTPFQREVWQALRAIPCGQVMHYGQLAAQLGRPGAARAVGAANGANPISIVVPCHRVIGRNGTLTGYAGGVQRKEWLLRHEGYLLL
What is the function of this protein?
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA.  Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme.  This is a suicide reaction: the enzyme is irreversibly inactivated.
What are the official names of this protein?
Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MGMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS4_STAAB
Sequence: MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSQFECVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYCIVGTKGIQDTDWLKEMAHTFPGRIYFSVDAYGEDIKVNGWEEDTELNLFSFVKQLSDIPLGGIIYTHIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAAIIGKAAHQASFWEGLK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POP4_YEAST
Sequence: MDRTQTFIKDCLFTKCLEDPEKPFNENRFQDTLLLLPTDGGLTSRLQRQQRKSKLNLDNLQKVSQLESADKQLEKRDYQRINKNSKIALREYINNCKKNTKKCLKLAYENKITDKEDLLHYIEEKHPTIYESLPQYVDFVPMYKELWINYIKELLNITKNLKTFNGSLALLKLSMADYNGALLRVTKSKNKTLIGLQGIVIWDSQKFFIMIVKGNIIDEIKCIPKKGTVFQFEIPISDDDDSALRYSILGDRFKYRSVDRAGRKFKSRRCDDMLYYIQN
What is the function of this protein?
Required for 5. 8S rRNA and tRNA processing; associated with RNase MRP and RNase P.
What are the official names of this protein?
RNases MRP/P 32.9 kDa subunit, RNA-processing protein POP4.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS3_XANC8
Sequence: MGHKVHPTGIRLGIAKDWNSKWYASKADFAAYLAADLKVREMLRKKLAQAGISKILIERPAKTARVTIHTARPGVVIGKRGEDIEKLRKEVSEMMGVPAHINVTEVRKPELDAQLVAESIAQQLERRIMFRRAMKRSVGNAMRLGALGIKVNVAGRLNGAEIARSEWYREGRVPLHTLRADIDYGFAEASTTYGIIGIKVWIYKGEVFDFSQVGQEKQDDSPRNDRNDRGDRGDRPSRPAREAR
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL2_YERPB
Sequence: MAIVKCKPTSPGRRHVVKVVNPELHKGKPYAPLLEKLSKSGGRNNNGRITTRHIGGGHKQHYRLVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGAYVQIVARDGSYVTLRLRSGEMRKVQADCRATLGEVGNAEHMLRVLGKAGASRWRGIRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: FRG2C_HUMAN
Sequence: MGKGNEDPDLHCSSIQCSTDQPPFQQISFTEKGSDEKKPFKGKGKTAFSHSSEKHTQRQAGSDPNPNKENSEETKLKAGNSTAGSEPESSSYQENCRKRKISSKDICQDRAGNCPEEECNLTLNKKSRSSTAVHNSEIQETCDAHHRGSSRACTGRSKRHRSRALEVQTPSLRKSLVTSVRAMSEAVYQDLAQVWAQQIHSPLTCEQLTLLTRLRGPLCAQVQTLYSMATQAAYVFPAESWLVPATLPGPGDSALDREAHPFPGQEITEPVSGSDEAKLGAP
What are the official names of this protein?
Protein FRG2-like-2, FSHD region gene 2 protein family member C, HSA3-FRG2.
What is the protein family that this protein belongs to?
Belongs to the FRG2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: COW2_CONLT
Sequence: MGKLTILVIVAAALLSTQFMVQGDGDQPADRDAVPSDDNPGGTSEKFMNVQHGSGCPWYPWCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Contryphan-Lt2.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.
Protein: NKPD1_MOUSE
Sequence: MQQEAAQRESEELQRVQWQPRRVRGWGVPKLLWFLVFLQPVITELHLRRRNVRFLFIRFSAWQYAGTDKLWAGLVTTLCEGIRHHYGALPFSVYSVLGNKPCGPRDGLCQREWHCRRRVCLALLALLAALCLGVGLLYLSLGGHAPGHGERGVLKALGGAATTLSGSGLLMAVYSVGKHLFVSQRKKIERLVSREKFGSQLGFMCEVKKEVELLTDFLCFLEIYQRRRLRVVLEVTGLDTCYPERVVGVLNAINTLLSDSHAPFIFILVVDPSILAACLESAGNMKGTADNGYLFLNRTVTLPFSVPIMGRRTKLQFLHDAVRSRDDLLFRELTIKLQPQSPGNLGAGEGTQLLAVETQGDAERTQGRVDAEAARRIQEALCCLHDEGDCLYEYVPDNVVSMRRIVNTVPITVRLLQQQQQQQPDRVGPTPRHAVAWVVLANQWPCRLSWVLQCLEDRQQAGGAPEGRSRLWDVFCDNSRELHTMTKALQNVLDLDGDPELFERFLGTDFPFTVAEAQSLLRCTVNLDHSIRRRMGLIRAVSALKPPSPPKSPSQDGPQASPRAIIAAGTSHAGQGSGHSKEAHQTRDRTHGGKPRPMA
What are the official names of this protein?
NTPase KAP family P-loop domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ATPF_LEPBJ
Sequence: MILLAAKGLSLLDVNPGLVVWTLITFLVVVLVLKKFAWDVILKALDERAQAVQNDIEKASELRLEAEALLKDYEARLNSAKDEANAIVAEARSDALKLKNKLLEETNQEVKAQKDQAVKEIELAKGKALEQLQTQFVEMTITIAGKVLEKQLKAEDYKAFIETELNKLGKLSA
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RODZ_CITK8
Sequence: MNTEATHDQNEAQSTGVRLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPVRPSKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVVGLTGAWWWQNHKAQQEELTTMVDQSSAELNAGGDSAQSVPLDTSEAASQDSTPAPTAPVDSTATNAVPQTPDASATTTAPAADAQQNAVVAPSQANVDTATTAPAATGDTASLPTDQAGVATSAVDQNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSPAQ
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: NTPPA_BACAA
Sequence: MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNKAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRAH4_ECOLX
Sequence: MSNPNEMTDEEIAAAMEAFDLPQPEPPSTPQAATATDGTLAPSAPAEPSHSASPTLDALDESRRPKAKTVCERCPNSVWFASPAELKCYCRVMFLVTWSSKEPNQLTHCDGEFLGQEEG
What is the function of this protein?
The initiation process of transfer DNA synthesis requires the interaction of at least three plasmid-specific components (TraH, TraI, and TraJ) at the transfer origin resulting in the assembly of a specialized nucleoprotein complex - the relaxosome.
What are the official names of this protein?
Protein TraH.
Protein: NFI_PYRAE
Sequence: MPPINIEAARRIQERLARQVTYAPLPPVETVAGLDVAYSGSLAFGAAVVVKRTTLEVVETACSVSRIVVPYVPTFLAFRELTPMLRAYIKLKSKPDVILVDGHGVAHPRRFGIASHIGVVLKKPTIGVAKSRLYGEEVGDKLVDPATGEVLALIIKCGGKKYVSVGSYATLDEAAGLVAQLCKSGDVYPLRLAHELANKLKKAHLPDDKDRDSCP
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_KARMG
Sequence: MNYCPRPKYLYKKKIINKLIEKFNYKSVMQVPKLKKIVINQGINVLIYDNKTINNAINNITAITGQKAIYCLSKRDESGFKLRKGTPISIKVTLRRDIMYEFLDRLINIALPRVRDFVGVNKNSFDGEGNYNLGISEQIIFPEINTDSLKNNFGMNITFVTSSKKNKEAKYLLYLFGLPFKTKKNV
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: NUSB_SHEPW
Sequence: MKPSERRKARRLAVQAIYSWQLSGNNIADVEHEFLTEQNVDGVDIAYFRELLGGVATKKSQLDELITPFLVRPMDEVDPVEKAIVRLAAYELTFRKDVPYKVAINEAIELAKAFGAEDGHKFVNGILDKLVARTK
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SPRTL_LISMF
Sequence: MNQAELQRHMEEVSLQFFQKEFRHQAVFNARLRTTGGRYLLKSHNIEMNPKYLENFGLAYFIGIMKHELCHYHLHLEKKGYQHRDQDFRELLKKVDAPRFCATIPREITMHEYTCKSCGKSFLRQRRFNVNRYRCGSCGGKLIQTGSKKIYTENA
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_CROS8
Sequence: MANYFNTLNLRQQLAQLGKCRFMARDEFADGAGYLKGKKVVIVGCGAQGLNQGLNMRDSGLDVSYALRKEAIAEKRASWRKATENGFQVGTYEELIPQADLVVNLTPDKQHSDVVRAVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKTIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFENAPQYEGKISEQEYFDKGVLMIAMVKAGVELAFETMVAAGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFANAAVPLLKEFMTKLQPGDLGKAVEGTAVDNAQLRDVNDAIRSHEIEKVGQKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MNHC1_STAAM
Sequence: MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit C1, Mnh complex subunit C1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SEC31_NEOFI
Sequence: MVRLREIPRTATFAWSPGAASPLIATGTRAGAVDVDFSNETCLELWDLGLSSQDASQELQPIAKIGTDSGFNDLAWTDSEDNSRGVIAGALENGSLDLWDADKLINGSSDAVISRMTKHSGAIKALQFNPKHSNLLATGGAKGELYISDLNNIANPYRLGSAAARADDIECLDWNKKVAHILVTGSSAGFVTVWDVKTKKESLTLNNMGRKAVSAVAWDPEKPTKLITSTPLESDPLIYVWDLRNSHAPERTLKGHESGVLSLSWCPQDPDLLLSSGKDNRTLCWNPQTGQAYGEFPVVTNWTFQTRWNPHNPNFFATASFDGRISIQTVQNTRTDTARAIADQNQALDGADFFAKAQTQPQVSNFSLPKAPKWLERPCGASFGFGGRVISVGLIEKGKRASKIKITPFEVDEAVAKSTETFENALKEGDLRSICENRASQAASDEEKADWKVIEALISENPRKGLIEYLGFQDQADETADKLAQLGLDKEDDEVNGESAKESRGSGAKKHKRLQSMFDANPEADNFLSDLAASKGAKTNNPFQIFNGSETEADKGITRALLLGNFEKALDVALKEDRMSDAFMIAICGGQKCIEKAQEHYFSKQTDGPNYIRLLASIVGKNLWDVVHNADLSNWKEVMAALCTFADDNEFADLCEALGDRLEEQIRSTEDKSLRKDASFCFLAGSKLEKVIAIWIEELREYEQKSIETAADDTSFSIHVRALQSLIEKVTIFRQVTKFQDTERTKDADWKLSMLYDKYIEYADVVATHGRLQVAQKYLDLVPEKHPEAEIARNRIKLAMRHATPQRSQQTVPTTRTPVNKPLPQASMYPAQPAFSATAAAPAAATTAPRNPYAPPTAATAQPVNPYAPPSAAATQPQTSNSYAPIGGGGYTPAGYQPLQPPTYGAQPLGGSVPPPPRASNQSPATVTTYTTATNLPAWNDLPEGFTKPPTSRRGTPAAAAATISSPFPNQSPTLSQGPPPPGAPPTQRAPSVPPPPKGTAPPPRVTSPPTNLPGPSPAANPYASLPQSPPMGSAMGVPPPASIPRGPSPYNAPPSMPPPSNRYAPSPAAQAASPQLSTRAPVPPPPHAAASPYASQPASHPPPANPYAPSTPPPSQLPMQQAPPPQAPPSRPSTASSQRKAAPAPPKYPPGDRSHIPSDAMPIYEILSADMQRVKSRAPSSFKAQVEDAERRLNILFDHLNNEDLLKPNTVADMAELARAIQARDYETAKTIHIDIMTNRTEECGNWMVGVKRLISMSRATP
What is the function of this protein?
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity).
What are the official names of this protein?
Protein transport protein sec31.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SEC31 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YCFP_SALTI
Sequence: MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLVSYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVVFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRHDEALDSQRSAQALHPFYEIVWDEEQTHKFKNISPHLQRIKAFKTLG
What are the official names of this protein?
UPF0227 protein YcfP.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: YQIJ_ECOLI
Sequence: MILFADYNTPYLFAISFVLLIGLLEIFALICGHMLSGALDAHLDHYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHACIMVWQSPLSNLFVVPVSLLFTIIAVHYTGKIVAPWIPRDHSSAITEEEYIGSMALITGHQATSGNPCEGKLTDQFGQIHYLLLEPEEGKIFTKGDKVLIICRLSATRYLAENNPWPQIL
What are the official names of this protein?
Inner membrane protein YqiJ.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FABA_SHEHH
Sequence: MSNANSFTKEDLIACGLGKLFGPNSPRLPKDNMLMIDRVLKINGDGGEYGKGEIVAELDINPELWFFDCHFAGDPVMPGCLGLDAMWQLVGFFLGWEGAEGKGRALGVGEVKFTGQVLPEAKKVTYKLTIKRKVYRKLVMGIADATMEVDGREIYSAKDLKVGIFTDTTSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUB51_ARATH
Sequence: MGDGALIVAVAIKGNNSKTKGVVRWALQEFASQEHVVFKLLHVQPRDSNSVSTTRKDLTTSVYKKDVDRKTREMLLPSRDMFVHREVQLDIMVLESDDIADAISKAVQDHGISELVIGASSSIIFSWKLKRSNLSSRIADATPRFCSVHVISKGKLLNVRKSDMDTETSIADDRSESRFSSDSHSGTVSSTSSHQFSSTPLLFQRIQALTTVNQKVGTNIGKQNNEPHHHHHNRAGSLDVDESKLLNQKGFYRTSSSGIGYGGSDISSWRSSQMEEASSSSTYSDPTSSSSQIHKDFELEKLKIELRHIKGMYAVAQSEVIDASKKMQDLNQRRSEEATRLKNLTIREEEADEVVEMERERQEDAENEAELVRECIERETEERLEAEARAEEVRKEKQRLEDALEGGPLQRQQYMKFEWEEIVEATSSFSDELKIGVGGYGSVYRCNLHHTTVAVKVLHSDKSSLTKQFHQELEILSKIRHPHLLLLLGACPERGSLVYEYMHNGSLEERLMKRRPNVDTPQPPPLRWFERFRIAWEIASALYFLHTNEPRPIVHRDLKPANILLDRNNVSKIGDVGLSKMVNLDPSHASTVFNETGPVGTFFYIDPEYQRTGVVTPESDIYAFGIILLQLVTARSAMGLAHSIEKALRDQTGKFTEILDKTAGDWPVKEAKEMVMIGLRCAEMRKRDRPDLGKEILPVLERLKEVASIARNMFADNLIDHHHNAPTHFYCPITKDVMENPCVASDGYTYEKRAIKEWLQKNHKSPMTDLPFPSDSLLPNHSLLSAIKEWRSQLIK
What is the function of this protein?
Functions as an E3 ubiquitin ligase.
What are the official names of this protein?
U-box domain-containing protein 51, Plant U-box protein 51.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: APT_HELP2
Sequence: MNETLKEELLQSIREVKDYPKKGILFKDITTLLNYPKLFNKLIDALKKRYLALNIDFIVGIEARGFILGSALAYALGVGFVPVRKKGKLPAHTLSQSYSLEYGSDSIEIHSDAFRGVKGVRVVLIDDLLATGGTALASLELIKALQAECIEACFLIGLKELPGIQLLEERVKTFCLLEC
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHLB_YERP3
Sequence: MSKTHLTEQKFSDFALHPLVVEALENKGFQYCTPIQALALPLTLSGRDVAGQAQTGTGKTLAFLASTFHYLLSHPAEEGRQTNQPRALIMAPTRELAVQIHSDAESLSQVTGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNYINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPSVDKRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPLQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRCIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILEDFTKGDLDILVATDVAARGLHIPLVTHVFNYDLPDDCEDYVHRIGRTGRAGESGHSISLACEEYALNLPAIETYTGHSIPVSKYNSDALLTDLPAPKRLARTRTGNGPRRNSAPRRSGAPRNNRKRPG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5M_CERCA
Sequence: MCSISFLVLVSISFSMFLLSLNFMLNEYCVFLEWEVVSLNSSGIVMTFLFDWMSLLFMSFVLLISSLVIYYSKEYINSSY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ARND_SHESH
Sequence: MSQQNVTKVGLRIDVDTYRGTRLGVPKLLEIFQRHDISASFFFTVGPDNMGRHIWRLLRPAFLKKMLRSKAASLYGWDILIRGTLWPGPIIGKKLAHIIKQADDAGHEIGLHAWDHHKWQMKTDVMTPAELHSEIDKGYQLLSTLTGKPIPCSAVAGWRCTDATLEQKQRFGFRYNSDCRGESIFIPQLGMAPQIPVTLPTYDELVGKDNIDHSNYNAEIIKLVNPDGLNVYTIHAEVEGIVCAQLFEELIIQAKENNIEFVPMIELLDHEDIDWPLDEILNIEIDGREGWLSHQASMINKQKSA
What is the function of this protein?
Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Probable 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family. ArnD deformylase subfamily.
Protein: NDHK1_ACAM1
Sequence: MQDQQIINPISQSQIPQELSENVILSSVSDLYDWARLSSLWPLMYGTACCFIEIAAMIGSRFDFDRFGLVPRSSPRQADLIITAGTVTMKMAPALVRLYEQMPDPKYVIAMGACTITGGMFSSDSTTAVRGVDKLIPVDVYLPGCPPRPEAVMDAIVKLRKKIANEDVRERGNLMQTHRYYSTTHQMKVVPPIHTGVYLEAAARKSPAAALGAGVGEDMTPALVAEAEKEEA
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit K 1, NAD(P)H dehydrogenase I subunit K 1, NDH-1 subunit K 1, NDH-K 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: V245_FOWPN
Sequence: MSVDWRTEIYSGDISLVEKLIKNKGNCINISVEETTTPLIDAIRTGNAKIVELFIKHGAQVNHVNTKIPNPLLTAIKIGSHDIVKLLLINGVDTSILPVPCINKEMIKTILDSGVKVNTKNAKSKTFLHYAIKNNDLEVIKMLFEYGADVNIKDDNGCYPIHIATRSNSYEIIKLLLEKGAYANVKDNYGNSPLHNAAKYGDYACIKLVLDHTNNISNKCNNGVTPLHNAILYNRSAVELLINNRSINDTDVDGYTPLHYALQPPCSIDIIDILLYNNADISIKDNNGRNPIDTAFKYINRDSVIKELLANAVLINEVGKLKDTTILEHKEIKDNTVFSNFVYECNEEIKKMKKTKCVGDYSMFDVYMIRYKHKYDGNKDSIKDYLRCLDDNSTRMLKTIDINEFPIYSMYLVRCLYEYGNILKEMGSCIHNRYKK
What are the official names of this protein?
Putative ankyrin repeat protein FPV245.
Protein: EXE2_HELSU
Sequence: MKSILWLCVFGLLIATLFPVSWQMAIKSRLSSEDSETDQRLFESKRHSDAIFTEEYSKLLAKLALQKYLASILGSRTSPPPPSR
What is the function of this protein?
Has vasoactive intestinal peptide(VIP)/secretin-like biological activity.  Interacts with rat and human VIP receptors 1 (VIPR1) and 2 (VIPR2), with the highest affinity for the human VIPR2.  Induces hypotension that is mediated by relaxation of cardiac smooth muscle.  This vasodilation may not be transduced by VIP or PACAP receptors.
What are the official names of this protein?
Exendin-2-long.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.