PharMolix/UniProtQA huggingface dataset:
Protein: YIDC_SHIFL
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIVAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYI_CUPNH
Sequence: MPDDKRAKPEKSKYPVNLLDTPFPMRGDLPKREPQWVKQWQDKQLYKKIRAARKGAKKFVLHDGPPYANGDIHIGHAVNKVLKDMIIKARGLTGLDAVYVPGWDCHGMPIEIQIEKKFGKGLPVQEVQAKARAYATEQIKRQMMDFERLGVLGDWDHPYLTMNYSNEADELRALGKIMEKGYVFRGLKPVNWCFDCGSALAEAEVEYKDKVDLSIDVGFPFAQADKLAHAFKVPFEQLDGKPGWIVIWTTTPWTIPSNQALNVHPEVEYALVETPRGYLILATERVEEQLKVYGLEGKVVATTTGAALSEIRFHHPLAKMDAGYDRLSPVYLGDYVTTDTGSGIVHSAPAYGVEDFQSCKAHGMADSDIISPVMGNGVYAGTLPLFGGLSIWDANPKIVEVLQASGNLFNSHKYTHSYMHCWRHKTPIIYRATSQWFAGMDVDPADENGKTGPTLRETALAGIDATEFFPAWGKQRLHNMIANRPDWTLSRQRQWGVPMAFFLHKETGALHPRTPQLLEEVARRVEQHGIEAWQTLDPAELLGDEASQYEKNRDTLDVWFDSGTTHWSVIRGSHRDDLYDPSADEADGRLADLYLEGSDQHRGWFHSSLLTASMLYGKPPYKALLTHGFTVDGEGRKMSKSIGNTVSPQDISNKMGAEIIRLWVASTDYSGELSISDEILKRVVEGYRRIRNTLRFLLSNLSDYDHARHALPASEWLEIDRYAVALTAQLQKEVLSHYEAYEFHPVVSKLQTFCSEDLGGFYLDVLKDRLYTTAPDSKARRAAQNALYHITQAMLHWMAPFLSFTAEEAWQIFAHGTEHTDTIFTSTYYAIPEVDDGADDLLQKWHTLREVRAEVTKQLEAVRVEGEIGSSLQAELTIQAGGPVLDALQSLGDDLRFVLLTSSAKVTHAPEAGDLLVTVTPSTHAKCERCWHYRADVGHNPDHPTLCGRCDSNLFGAGEHRSHA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUD12_PONAB
Sequence: MSSVKRTPKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSNLNPLVTLGGNKESFQQPEVRLCQLNYTDIKDYLAQPEKITLIFLGVELEIKDKLFNYAGEVPREEEDGLVAWFALGIDPIAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWYSRYKFCPTCGNATKIEEGGYKRVCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIEDAHWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some RNAs; in contrast to the canonical N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay.  Preferentially acts on NAD-capped transcripts in response to nutrient stress (By similarity).  Also acts on free nicotinamide adenine dinucleotide molecules: hydrolyzes NAD(H) into NMN(H) and AMP, and NADPH into NMNH and 2',5'-ADP.  May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle (By similarity).  Regulates the levels of circadian clock components PER1, PER2, PER3 and CRY2 in the liver (By similarity).
What are the official names of this protein?
NAD-capped RNA hydrolase NUDT12, DeNADding enzyme NUDT12, NADH pyrophosphatase NUDT12, Nucleoside diphosphate-linked moiety X motif 12, Nudix motif 12.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome. Cytoplasmic granule. Note=Localizes to cytoplasmic granules in the presence of BLMH.
Protein: GLMU_ALKCK
Sequence: MSGRFAVILAAGQGTRMKSKLYKVLHPVCGKPMVEHVVDQVSKLEFDKTAVIVGHGAEEVKKTLTEKIEFVMQPEQLGTGHAVKCAEHLLASQKGTTVVLCGDTPLITAATIKKLMDTHEANGAKATVLTAHAPDPTGYGRVIRGNQGQVEKIVEHKDASVDELAIAEVNTGTYCFDNEALFEALAEVKNENAQGEYYLPDVIGILRQKGETISAYQTDSLSETMGVNDRVALSQAEAAMRKRINEEWMRQGVTIIDPQTTYISADASIGQDTVLYPNTSIKGPSVIGEDCVIESGTEIASATLGRGVHVCSSVISNSVVADGSSIGPFAHIRPGSDVGENVRVGNFVELKKASIGTGSKVSHLTYVGDAEVGSDVNVGCGVVTVNYDGKNKHKTIIKDGAFVGSGSNLIAPVEIGERAFVAAGSTITDDVPSQALSIARSRQVNKDNYVKKDV
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BR1D_LITPI
Sequence: FLPIIASVAANVFSKIFCAISKKC
What is the function of this protein?
Antibacterial activity against Gram-positive bacterium S. aureus and Gram-negative bacterium E. coli.  Has activity against C. albicans.
What are the official names of this protein?
Brevinin-1Pd.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: LIPB_HAEDU
Sequence: MNHLIIRQLGIQPYERIWHQMQDFTDQRDEHSADEIWLVQHPAVFTQGSAGKSEHLLTSSHIPVVQTDRGGQITYHGEGQQIMYVLIDIKRLKAQGKDISVRELVTALEQCVVRTLEDYGIDGYPKPDAPGVYIEGKKICSLGLRIRKGCSFHGLAFNVNMDLTPFSHINPCGYAGLEMTQLKDYISEDNAQCKLVASKLVAHFCNILGYNSQKITNKSEIQAV
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSA_ENTFA
Sequence: MAKTGMYVGLDIGTTSVKVVVAEYIEGQMNIIGVGNAKSDGLNRGIVVDIDQTVQAIQRAVRQAEEKAGIQIKSVNVGLPANLLEVESCQGMIAVSSESKEITDEDVRNVASAALVRSTPPERQIVAILPQDFTVDGFEGIKDPRGMLGVRMEMFGVVYTGPKTIIHNIRKCVEKAGLGINELVITPLALTETILTDGEKDFGTIVIDMGGGQTTTSVIHDKQLKFTHVNQEGGEFITKDISIVLNTSFNNAEALKINYGDAYPERTSANEEFPVDVIGKSEPVRVDERYLSEIIEARVEQILRKSKEVLDEIDAFELPGGVVLTGGAASMPGIVDLAQEIFEANVKLYVPNHMGLRNPVFANVISIVEYSAQLNDIYHIAKYAIPGEKSKPAQSVAVQQEVRYDTYAEQPQEEYEEFNERESGEKVTGKIKDFFSNIFD
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: Y2398_LACP7
Sequence: MNKKVEGLTKETEAANYLSEQGYQILARNYRCRLGEIDIVARENGYLVFVEVKYRTNVEKGFPEEAITIQKQRRITNTAKYYLLVNRLPESTPCRFDVVVMLKEEIRLIKNAFDAYGS
What are the official names of this protein?
UPF0102 protein Cphy_2398.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: DTM1_ORYSJ
Sequence: MGRDEMLRRSLVALAAAVVVTGVVTASVRKAAATYGFGILAIAGVLLPDWEFFDRDYSQWLTPMPASRRTAAEAAADREHDVWKFKPYPLRMAMLTTIYGFGLYKWWMYVSS
What is the function of this protein?
Functions in tapetum development during early meiosis.  May play a role in the endoplasmic reticulum (ER) membrane in the early stages of tapetum development in anthers.  Seems to function after MSP1 and before UDT1.
What are the official names of this protein?
Signal peptidase complex-like protein DTM1, Protein DEFECTIVE TAPETUM AND MEIOCYTES 1.
What is the protein family that this protein belongs to?
Belongs to the SPCS1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NTPPA_CHESB
Sequence: MSAPTKLILASASPRRVQLLQQAGLEPNRLVPAEIDETPLKAEHPRSLAKRLARSKAEKALERLRKDGEERDSFVLAADTVVAVGRRILPKTEIADEASNCLRLLSGRSHRVYTGICLFTPTGKLRHKLVETRVRFKRISREELEAYIASGEWRGKAGGYAIQGLAGSFVVKLVGSYTNVVGLPLHETVSLLAADGFKAYLNWPAGTQV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_STAAR
Sequence: MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAINKHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQARVILMCPQGEPFSHQKAVELSKADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGNEQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKRPDLIEKYPLTNADKQILERYKIGLKKG
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HNR_EUBBA
Sequence: MFKIDEEKCKKCRMCVKECPVHAVYYEKKDKGAIVEITEKCVECGICKRVCKFGAIENDAPLESVITCSSCPIQCKVPLGETGACTRYRNVGGKLVRDRELVVEALEQKEAADNIKKPIITAVGAGTNYPCSKPAPHIVSECRDGVDVVTVVTEAPLSYSGLVIKLDTNTYIGEEGDPVYRDGKVVGMVNTEEYGSKMIAIGGANRLTGDNGFATARTIVELANGEEVELKVNKKIVLKLKAGVAPVIDGVEESIMRIGCGSATVGLFAKRMKDAVDECIVIDHHVIGLCSEHLAGEAVGMTWSGIIPNATKSSRGRYFGGHGSGIGGTSLETPRDAIKGADMSIAKAGMQVMVVNTTGEIYALFELKADGSFDEIPMTEAALGVALAIQDNCQRSMTSILYTGGTGGSARGGVCTHPVKITEAVHEQKAVLTIGGAPAFVYPGGGINFMVDTQKVVNKAFTWVPTPATVAPVEYTMTVADYEAMGGHMDQIKDVSEYK
What is the function of this protein?
Catalyzes the reversible reduction of 6-hydroxynicotinate to 6-oxo-1,4,5,6-tetrahydronicotinate.
What are the official names of this protein?
6-hydroxynicotinate reductase.
Protein: RL25_IDILO
Sequence: MAELDFNIQATVRTDKGKGASRRLRHEDKVPAILYGGQGEPIALALDHNKVNNMADYEAFYSHIVTLEFDGKKHQAILKDMQRHPYKPKLTHLDFQRVEKGHKLHTNLPLHFLNETTAKGVKEEGGVVVHHVNDVEITVLPKDLPEYLEVDIAELSVGDTIHLTDLKLPKGVELVELTKGEDHDQAVVSITAPRVEKEETEEDTVAPGDVPAENSKDADEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: UGPA_ASTPN
Sequence: MATATATDRLSNLKSSVAGLNQISENEKSGFINLVARYLSGEAQHVEWSKIQTPTDEVVVPYDTLAPTPDGSLEIKNLLDKLVVLKLNGGLGTTMGCTGPKSVIEVRDGLTFLDLIVIQIENLNSKYGSNVPLLLMNSFNTHDDTQTIVEKYQNSNIEIHTFNQSQYPRLVVDDFLPLPSKGRTDKDGWYPPGHGSMFPSLSNSGKLDALISQGKEYVFVANSDNLGAIVDLKILNHLVAHKNEYCMEVTPKTLADVKGGTLISYEGRVQLLEIAQVPDEHVGEFKSIEKFKIFNTNNLWVNLKAIKRLVEADALKMEIIPNPKEVDGVKVLQLETAAGAAIRFFDKAIGINVPRSRFLPVKATSDLLLVQSDLYTVENGSVIRNKARTNPENPSIELGPEFKKVSNFLGRFKSIPSIVELDSLKVVGDVWFGTGVILKGKVSIVAKSGVKVEIPDGAVIANKEINGPKDL
What is the function of this protein?
Plays a central role as a glucosyl donor in cellular metabolic pathways.
What are the official names of this protein?
UTP--glucose-1-phosphate uridylyltransferase, UDP-glucose pyrophosphorylase, UDPGP, UGPase.
What is the protein family that this protein belongs to?
Belongs to the UDPGP type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAM10_CAEEL
Sequence: MPPQVIQQQQQSLASEMTARDRLTSYIYEYLQQTGASKTAETFKEEVLSTNPAAGLAAANSTKLSDKSFLLEWWLLFWDLYSAAPERRDAGGDPFSAEAKYFHEAMIGMPPGMNGHFAPPPMGMEMMGGHPGAFGGRFAPGRMPPGAMAPGGMPPGAFPMFPPDPRLQRMAPNQGMRMPPPPVGQPFPGAVGMPRPVGPGAPMDMSGMQRFDFMGGPPPGGGAQPFPGASGSGGMMPNGAHPHMSLNSPSMGVPPADMPPFMGMPPMPPTSSSAMPFGMSSDHQPMSAGPAAAAPGATTAGGPGTPGMIGSVPGPGSVPQVATTSVGSVGTPSSIGQQLHQPKQEITTNGEEIMKTEALTPTGGGGGGSVPPPPPAATAAVSMNGGGPGSAPGSAHSVNNNVNPGTPGSNPLSNPMSNPPLSSGPPPPGSNDAFGKDDNGEISKIREGLLDGFCA
What is the function of this protein?
Involved cell autonomously in PLM neuron pre-synaptic differentiation by negatively regulating prk-2 expression and in neurite branch positioning.
What are the official names of this protein?
Single-stranded DNA-binding protein homolog sam-10, Synaptic vesicle tag abnormal in mechanosensory neurons.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=In PLM neurons, translocates into the nucleus during the 3-fold embryonic stage and remains nuclear in the adult. Nuclear localization is idb-1-dependent.
Protein: NEUT_RANTE
Sequence: QSHISKARRPYIL
What is the function of this protein?
Smooth muscle-contracting peptide.
What are the official names of this protein?
Neurotensin, NT.
What is the protein family that this protein belongs to?
Belongs to the neurotensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPMI_EHRRG
Sequence: MTNHSVILCILDGWGNNKNSQFNAIAQADTPYWDSIISQYPQSNIVTHGPDVGLPDRQIGNSEVGHISLGSGRIVLQDLCRINEEIKNIRKNTHLLEFTEQIKRNNGICHIAGLLSDGGIHSSLSHMLDIIDALSYLKIQVVIHIFLDGRDTPPISALKYINILCSHIKDLNNVSIATISGRYYSMDRDNRLDRTTKAYNSIAFGDGKRYEEPISAVQDNYNAGITDEFIIPCVIGNYQGMNPTDGFIMTNFRSDRVIQILKMITEDQNTNHITLKNTIGMIKYSNELNIPCLFPNKKISNTLGEIISNQQLHQLRIAETEKYAHVTFFFNGGREEVFENEERIIIPSPSVTTYDLVPEMSAYEITDTLIKKINLQKYSLIIINYANADMVGHTGNIEATKKAITTLDQCLGKILKCIHNTNYILVITADHGNAEEMFDVQNNMPYTAHTLNPVPFVVCNYPKKIKLKNGRLSDVAPTILEILNIKQPEEMTGISLIDTSN
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RL323_ENTFA
Sequence: MAVPARRTSKAKKAKRRTHYKLTIKGLNACSNCGEMKKSHHVCPACGHYDGKDVMSKEA
What are the official names of this protein?
50S ribosomal protein L32-3.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: MBTD1_XENTR
Sequence: MEKTKDLADLSSLSERKRRDSFGMFDGYDSCSEDTSSSSSSDESEEEVAPLPSSLPIIKNNGQVYTYPDGKSGMATCEMCGMVGVRDAFYSKTKRFCSVSCSRSYSSNSKKASILARLQGKPPTKKAKVLQKKPLVAKLAAYAQYKATLKNQSVNKAPVTVEGFSWGNYITSNNTAAAPVTCFRHAPMGNCWGDIAEGVRVEVPNTDSNLPTKVFWISGIVKLAGFNALLRYEGFENDSSLDFWCNICGPDVHPVGWCATSGKPLVPPQTIQHKYTNWKAFLVKRLTGAKTLPPDFSQKVSESMQYPFKPSMRVEVVDKTHLCRTRVAVVDSVIGGRLRLVYEESEDKTDDFWCHMYSPLIHPIGWSRSIGHRFKRTDILKKQESNYDAPSHLFTKVKDIEQGSEWFKEGMKLEAIDPLNLSAICVATIRKVLADGYLMIGIDGSEAADGSDWFCYHASSPSIFPVGFCEINKIELTPPRGYTKLPFKWFDYLRETGSIAAPVKLFNKEVPNHGFRVGMKLEAVDLMEPRLVCVATVTRIIHRLLRIHFDGWEDEYDQWVDCESSDLYPVGWCQLTGYQLQPPAPQSNKDSQSNISKQKKKSKSQPYKGHKKITALQLKDEMLDGDDYTFLQGASDQESNGSGSYYIKQEP
What is the function of this protein?
Chromatin reader component of the NuA4 histone acetyltransferase complex, a multiprotein complex involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.  The NuA4 complex plays a direct role in repair of DNA double-strand breaks (DSBs) by promoting homologous recombination (HR).  MBTD1 specifically recognizes and binds monomethylated and dimethylated 'Lys-20' on histone H4 (H4K20me1 and H4K20me2, respectively).  In the NuA4 complex, MBTD1 promotes recruitment of the complex to H4K20me marks by competing with TP53BP1 for binding to H4K20me.  Following recruitment to H4K20me at DNA breaks, the NuA4 complex catalyzes acetylation of 'Lys-15' on histone H2A (H2AK15), blocking the ubiquitination mark required for TP53BP1 localization at DNA breaks, thereby promoting homologous recombination (HR).
What are the official names of this protein?
MBT domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL10E_METM7
Sequence: MALRPARCYRTTERRSYTRKEYVRAVPQPKVVHYVMGNSSVEFPVEVQLISKSDILIRHNALESSRIAGNKYILRECGRTGYLFNIRVYPHEILRENKMAAGAGADRISDGMRLSFGKAVGTAAKVKKGQEIITIGVNPEKFYAAKEALRRCSMKLPTACKIVVTKGQDLIRD
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ARAN_BACSU
Sequence: MKKMTVCFLVLMMLLTLVIAGCSAEKSSGKSGETELTFWTFNGLHEQFYVEMVKEWNKKYPDRKIKLNTVVYPYGQMHDNLSISLIAGEGVPDIADVELARFSNFLKGSDIPLADLTPLIEKDRDKFVEARLTLYSKNGKLYGLDTHVGTTVMFYNMDVMKKAGVNPDDIKTWDDYHKAGQKVRKVTGKPMGTVETNDSATFLSMISQQNSGYFDKNGKLILNNDTNVKTLQYLKDMINDKTMIPAPGGGHHSEEYYGFMNQGGAASVLMPIWYMGRFIDYMPDLKGKIAIRPLPAWKEGGDRSAGLGGTATVVPKQSKHVELAKEFLAFAKGSEEGNKKLWSVLGFDPLRWDVWSSKELKEKNKYTDYFQNGTGIFSVLLDIKDEINPIYLHEDFAKASDLVNRSVLFDALKSQQKTPKQALDRAAGELKQK
What is the function of this protein?
Part of the ABC transporter complex AraNPQ involved in the uptake of arabinooligosaccharides.  Transports alpha-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units (PubMed:20693325).  AraN captures the substrate and delivers it to the two transmembrane components (Probable).
What are the official names of this protein?
Arabinooligosaccharide-binding protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: NFYC2_ORYSJ
Sequence: MDNQQLPYAGQPAAAGAGAPVPGVPGAGGPPAVPHHHLLQQQQAQLQAFWAYQRQEAERASASDFKNHQLPLARIKKIMKADEDVRMISAEAPVLFAKACELFILELTIRSWLHAEENKRRTLQRNDVAAAIARTDVFDFLVDIVPREEAKEEPGSALGFAAGGPAGAVGAAGPAAGLPYYYPPMGQPAPMMPAWHVPAWDPAWQQGAAPDVDQGAAGSFSEEGQQGFAGHGGAAASFPPAPPSSE
What is the function of this protein?
Probable transcription factor involved in the regulation of flowering time under long day (LD) conditions.  Functions as repressor of flowering, independently of HD1 and GHD7.  Controls flowering time by negatively regulating the expression of EHD1 and HD3A (PubMed:26542958).  Component of the NF-Y/HAP transcription factor complex (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit C-2, OsNF-YC2, Transcriptional activator HAP5C, OsHAP5C.
What is the protein family that this protein belongs to?
Belongs to the NFYC/HAP5 subunit family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: SUB1_PLAFO
Sequence: MMLNKKVVALCTLTLHLFCIFLCLGKEVRSEENGKIQDDAKKIVSELRFLEKVEDVIEKSNIGGNEVDADENSFNPDTEVPIEEIEEIKMRELKDVKEEKNKNDNHNNNNNNISSSSSSSSNTFGEEKEEVSKKKKKLRLIVSENHATTPSFFQESLLEPDVLSFLESKGNLSNLKNINSMIIELKEDTTDDELISYIKILEEKGALIESDKLVSADNIDISGIKDAIRRGEENIDVNDYKSMLEVENDAEDYDKMFGMFNESHAATSKRKRHSTNERGYDTFSSPSYKTYSKSDYLYDDDNNNNNYYYSHSSNGHNSSSRNSSSSRSRPGKYHFNDEFRNLQWGLDLSRLDETQELINEHQVMSTRICVIDSGIDYNHPDLKDNIELNLKELHGRKGFDDDNNGIVDDIYGANFVNNSGNPMDDNYHGTHVSGIISAIGNNNIGVVGVDVNSKLIICKALDEHKLGRLGDMFKCLDYCISRNAHMINGSFSFDEYSGIFNSSVEYLQRKGILFFVSASNCSHPKSSTPDIRKCDLSINAKYPPILSTVYDNVISVANLKKNDNNNHYSLSINSFYSNKYCQLAAPGTNIYSTAPHNSYRKLNGTSMAAPHVAAIASLIFSINPDLSYKKVIQILKDSIVYLPSLKNMVAWAGYADINKAVNLAIKSKKTYINSNISNKWKKKSRYLH
What is the function of this protein?
Serine protease which plays an essential role in merozoite invasion of and egress from host erythrocytes by processing and activating various merozoite surface and parasitophorous vacuole proteins.  Mediates the proteolytic maturation of serine proteases SERA4, SERA5 and SERA6 just prior to merozoite egress.  Prior to merozoite egress, cleaves merozoite surface proteins MSP1, MSP6 and MSP7, which form the MSP1/6/7 complex, and thereby may prime the parasite cell surface for invasion of fresh erythrocytes.  Prior to merozoite egress, cleaves MSRP2 converting it to MSRP2 p25 form, and RAP1 converting it to RAP1 p67 form.
What are the official names of this protein?
Subtilisin-like protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted. Parasitophorous vacuole lumen. Note=At the schizont stage, in merozoites, localizes to dense secretory granules called exonemes (PubMed:29074774). Just prior to egress secreted into the parasitophorous vacuole (By similarity).
Protein: 069R_FRG3G
Sequence: MERSATLEMLNVHKPDARQTGDILSRYANALWPPALAYAASVAAGYVFTAGPHGCRCGKAMTEAARVGVFLGVLCALYNWMGSGDSFA
What are the official names of this protein?
Transmembrane protein 069R.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: PURL_ALKMQ
Sequence: MTNQYEAVGLKAKEYEGIVEMLGREPNELELNLYGVMWSEHCSYKHSRSMFKHFPTSGPSVLQGPGENAGIVDIGDGLAIAMKIESHNHPSAIEPYQGAATGVGGIIRDIFAMGARPIALLNSLRFGELEGDARVKYLLEGVVEGIAGYGNCMGIPTVGGEVYFNQSYRGNPLVNAMCVGLIEHDAIHRGTASGVGNSIMYVGAATGRDGIGGASFASATLTEESEEKRAAVQVGDPFMEKLLLEACLELLKTGSIIGIQDLGAAGLVSACCETATRGEGGMEIDVLKVPRRETGMVPVEVMISESQERMLLIVERGREEEVNEIVKKWGLHSVIIGRVTNDDKLRIFEGDKVVGEIPAESLDSSGAPRYEPDYAPPADLAELQKLDIESIPEPRDLSSTLRKLLASPNIASKEWIYRQYDHMVRTNTVIKPGSDAAVLRIRGTKKGIALTTDCNSRYCYLDPREGSKIAVVEAARNIVCSGGKPIAITDGLNFGSPETPEGYWQFRESVLGLSEACREMDTPVISGNVSFYNQTEKGSIHPTPIVGMVGLIEDISKTCTMAFKEAGDIIVLLGQTKAEIGGSEYLASIHGQEKGKIPHLNLSLEKRLQKEVLALIQGDLVQSAHDLSEGGLAVGVAECAIAGGIGARVEVNTELRNDIVLFSESQSRFLMTIKPEHLETVQERLKQSNIPHEQLGTVIGNELQMQINGNVVVKESIGELEEIWRGALQCLMESMKID
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.