PharMolix/UniProtQA huggingface dataset:
Protein: TAOK2_XENLA
Sequence: MPSNARAGNLKDPEVAELFFKDDPEKLFADLREIGHGSFGAVYFARDIRNNEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPNTIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEMEIAAITHGALQGLAYLHNHNMIHRDVKAGNILLTEPGLVKLGDFGSASIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITSIELAERKPPLFNMNAMSALYHIAQNESPVLQSNHWSEYFRNFVDSCLQKIPQDRPTSDMLLKHRFLQRERPQTVIMELIQRTKDAVRELDNLQYRKMKKILFQDTQNGPNTETTEEEEEAEQFLHCTGTITSMESSQSVPSMSISASSQSSSVNSLADASDDSGEMAMMQEGEHTVTSNSSVIHRLPAHDNIYDDPYQPEMEAQQSSSAARRRAYCRNRDHFATIRTASLVTRQIQEHEQDSALREQMSGYKRMRRQHQKQLMALENKLKSELDEHQQRLDKELEAHRSNFSAENEKISKKHQAIFEKEAKGGMTEEKKFQQHILGQQKKELTNLLESQKRQYKIRKEQLKEELQENQSTPKREKQEWLLRQKESMQHYQAEEEANLLRRQRQYFELQCRQYKRKMLLARHNLDQDLLREELNKKQTQRDLECAMLLRQHECTQELEFRHLQLLQHTRSELIRMQHQTELGNQLEYNKRREQELRQKHAAEVRQQPKSLKSKELQIKRQFQDTCKIQTRQYKALRNHLLETTPKSEHKSILKRLKDEQTRKLAILAEQYDHSINEMLSTQALRLDETQEAEYQELRIQLQKELELLNAYQSKIKIHTDAQHERELKELEQRVSIRRALLEQRIEEEMLALQTERSERIRSLLERQAREIEAFDSESMRLGFSNMALTGIPAEAFNQGYQAPPPGWPSRPVPRSGSHWSHGVQNTGAPQLWRQPTLLAPPSASWGLHPPGSSSSLSALPSSSSSSSSSPSSSSGGRPGLLLLRNSPQPLRRGGSGGPSEAGLSRSTSVTSQLSNGSHLSYS
What is the function of this protein?
Activates the JNK MAP kinase pathway.
What are the official names of this protein?
Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
Protein: ACCD_PROM3
Sequence: MSLFDWFADRRKGQFVGKVSQETEESDGLWVKCPECGQVVYRKDLHANASVCSNCGYHHRIDSDERIVLIADQGSFKSLDRNLSPTDPLGFKDRRAYADRLRESQASTGMKDGVVTGLCQVEGMPMAMAVMDFRFMGGSMGSVVGEKITRLVERATAQGLPLLIVCASGGARMQEGMLSLMQMAKISGALERHREAELLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIEQTLREKLPDNFQTAEYLQEHGFVDTIVPRTQLRKTLASLLLLHGCKAKKAAGK
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IC1_RAT
Sequence: MASKLTPLTLLLLLLAGDRAFSDSEVTSHSSQDPLVVQEGSRDSVPERDGSRSPIEHTGQSSTWPTTSGSTKISNDTMDQVANESFIQHVQPAAQLPEDSPSQSPVNSSSPPSTASAPPTQAPTEPLCPEPLAWCSDSDRDSSEATLSEALTDFSVKLYHAFSATKKAETNMAFSPFSIASLLTQVLLGAGDSTKSNLEDILSYPKDFACVHQTLKAFSSKGVTSVSQIFHSPDLAIRDTYVNASLSLYGSSPRVLGPDGDANLKLINTWVAENTNHKINELLDSLPSDTRLVLLNAVYLSAKWKKTFEQKKMMASFLYKNSMIKVPMLSSKKYPLALFNDQTLKAKVGQLQLSHNLSFVIMVPQSPTHQLEDMEKALNPTVFKAILKKLELSKFQPTYVMMPRIKVKSSQDMLSIMEKLEFFDFTYDLNLCGLTEDPDLQVSSMKHETVLELTETGVEAAAASTISVARNLLIFEVQQPFLFLLWDQRHKFPVFMGRVYDPRA
What is the function of this protein?
Activation of the C1 complex is under control of the C1-inhibitor.  It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases.  May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins.  Very efficient inhibitor of FXIIa.  Inhibits chymotrypsin and kallikrein (By similarity).
What are the official names of this protein?
Plasma protease C1 inhibitor, C1 Inh, C1Inh, C1 esterase inhibitor, C1-inhibiting factor, Serpin G1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MIOX5_ARATH
Sequence: MNISVENPVFVHEDSTTQKTGELRLDSDIPMSKISSDDEVFLAPEMNAFGRQFRDYTDTNSERQKSVEHFYATQHTNQTLDFVQKMRSEYGKLDKMVMNIWECCELSKEVVDESDPDLDEPQIQHLLQSAEAIRKDYPNEDWLHLTALIHDLGKVLTLPQFGGLPQWAVVGDTFPVGCAFDESNVHHKYFMENPDFNNPKYNTKAGIYSEGCGLENVLMSWGHDDYMYLVAKENGSTLPSPGLFIIRYHSFYPLHKAGAYTHLMNEEDKENLKWLHVFNKYDLYSKSKVHVNVEKVKPYYMSLIKKYFPENLRW
What is the function of this protein?
Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers.  May be also involved in plant ascorbate biosynthesis.
What are the official names of this protein?
Inositol oxygenase 5, Myo-inositol oxygenase 5, AtMIOX5, MI oxygenase 5.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol oxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_PSEA6
Sequence: MRGYLLEFATIFTETLLFIMPYIHSLSATELASNSQKKVIVGMSGGVDSSVSAYILLQQGYQVEGLFMKNWEEDDNDEYCAAADDLKDAQAVADKLGIVLHQINFAAEYWDNVFEYFLEEYKSGRTPNPDIMCNKEIKFKAFLEFAAEELEADYIATGHYVRRREVDGHWQMLRGMDDNKDQSYFLYTLGEQHVGQTLFPIGDIEKPQVREIAQEQGLITHDKKDSTGICFIGERKFTDFLSQYLPAQPGVIETPEGQEIGQHQGLMYHTLGQRKGLMIGGMKEFGDDPWYVVDKDMARNVLIVGQGADHPRLYSNGLIANQLHWVDRTGPTSPMKCSVKTRYRQEDIACTLTPEPDGNVRVMFDEPQKAVTPGQSAVFYLNEVCLGGGIIESYIR
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH3_GEOKA
Sequence: MSNYVIQADQQLLDALRAHYQDALSDRLPAGALFAVKRPDVVITAYRSGKVLFQGKAAEQEAGKWMVKRGADPGKRQERETASPPLEHRLEKLSAIGSDEVGTGDYFGPIVVAAAYVDRSHIAKIAALGVKDSKQLTDEAIHKIAPAIMETAPYAVTVLDNAEYNRWQRSGMPQTKMKALLHNRTLAKLVDAIAPIEPEAIIIDQFLERGSYFRCLADETRIVSDRVHCLPKAESVHVAVAAASIIARYVFLEEMERLSRTVGLLLPKGAGAIVDEAAARIIRERGAEALETCAKLHFANTKKALDIAKHR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_PSEMY
Sequence: MTEARKILVTSALPYANGSIHLGHMLEYVQTDMWVRYQKLRGNQAIYVCADDAHGSAIMLRAEKEGITPEQLIDGVRAEHMADFADFGVDFDNYHSTHSQENRELSASIYLALRDKGHIATRAVTQYFDPEKGMFLADRFIKGSCPKCGAEDQYGDNCEKCGATYTPTELKNPRSAISGAVPVLKESQHFFFKLPDFEAMLKQWTRSGALQEAVANKIAEWLDGGLQEWDISRDAPYFGFEIPGEPGKYFYVWLDAPIGYMASFKNLCSKRPELDFDAFWGKDSTAELYHFIGKDIVNFHALFWPAMLEGAGYRKPTAVNVHGYLTVNGQKMSKSRGTFIKARTYLDHLNPEYLRYYYASKLGRGVDDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNDGLLVAANPEPELWDAFQAAAPSIAEAYEARDFSRAMREIMALADRANAWIADKAPWALNKVEGKQAEVQEICALGINLFRQLVIMLKPVLPKLAADAEAFLNVKPQTWADLSLPLANHQLNPFNPLLTRIEPAKIEAMVEASKEDLAAEASKPQGNGELAKDPLAAEINFDAFAAVDLRIALIEKCEFVEGADKLLRLSLDIGDEKRNVFSGIKSAYPDPSKLEGRLTLYVANLAPRKMKFGISEGMVLAAGPGGEEIYLLSPDSGAKPGQRVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRB_THET8
Sequence: MSYDASAIRVLKGLEGVRHRPAMYIGGTGVEGYHHLFKEILDNAVDEALAGYATEILVRLNEDGSLTVEDNGRGIPVDLMPEEGKPAVEVIYTTLHSGGKFEQGAYKVSGGLHGVGASVVNALSEWTVVEVFREGKHHRIAFSRGEVTEPLRVVGEAPRGKTGTRVTFKPDPEIFGNLRFDPSKIRARLREVAYLVAGLKLVFQDRQHGKEEVFLDKGGVASFAKALAEGEDLLYEKPFLIRGTHGEVEVEVGFLHTQGYNAEILTYANMIPTRDGGTHLTAFKSAYSRALNQYAKKAGLNKEKGPQPTGDDLLEGLYAVVSVKLPNPQFEGQTKGKLLNPEAGTAVGQVVYERLLEILEENPRIAKAVYEKALRAAQAREAARKARELVRRQNPLESDELPGKLADCQTENPEEAELFIVEGDSAGGSAKQGRDRRFQAILPLRGKILNVEKAGLSKALKNAEVRAMVSAIGVGIGGDGEAHFDLEGLRYHKIIIMTDADVDGSHIRTLLLTFFYRYMRPLIERGHVYIAQPPLYRLQVGKKVEYLYSDEELQARLKELEGKHYEVQRFKGLGEMNPEQLWETTMNPEKRVLKRVELQDALEASELFEKLMGQEVAPRREFIEEHARYAELDI
What is the function of this protein?
Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_MYCBP
Sequence: MSVLLFGVSHRSAPVVVLEQLSIDESDQVKIIDRVLASPLVTEAMVLSTCNRVEVYAVVDAFHGGLSVIGQVLAEHSGMSMGELTKYAYVRYSEAAVEHLFAVASGLDSAVIGEQQVLGQVRRAYAVAESNRTVGRVLHELAQRALSVGKRVHSETAIDAAGASVVSVALGMAERKLGSLAGTTAVVIGAGAMGALSAVHLTRAGVGHIQVLNRSLSRAQRLARRIRESGVPAEALALDRLANVLADADVVVSCTGAVRPVVSLADVHHALAAARRDEATRPLVICDLGMPRDVDPAVARLPCVWVVDVDSVQHEPSAHAAAADVEAARHIVAAEVASYLVGQRMAEVTPTVTALRQRAAEVVEAELLRLDNRLPGLQSVQREEVARTVRRVVDKLLHAPTVRIKQLASAPGGDSYAEALRELFELDQTAVDAVATAGELPVVPSGFDAESRRGGGDMQSSPKRSPSN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NIKR_BRUC2
Sequence: MQRITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQMEACVGVLSYTYDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKGKTDDVRHFADHVKAERHVTHGTLAVLPL
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: SAHH_VARPS
Sequence: MSAVLKPTPVSTADQAIADLSLAAWGRKEIKIAETEMPGLMAIREEFSKAQPLKGARITGSLHMTIQTAVLIETLQALGATVRWASCNIFSTQDHAAAAIAAAGTPVFAIKGESLKDYWDYTHAIFDFGPKGSQGEGPNMILDDGGDATLLMHLGQRAEKDLGVLSKPTSEEERILYAAIKAKLAVDPTWYTRKSAEIIGVTEETTTGVHRLNEMSAKGTLLFRAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKVACVAGYGDVGKGSAQALRALSAQVWVTEIDPINALQAAMEGYKVVTMEYAADKADIFVTTTGNRDVIRHEHMAAMKDQAIVCNIGHFDNEIDVASIEKYEWEEIKPQVDHITFPDGKKIILLAKGRLVNLGCGTGHPSFVMSSSFANQTIAQIELFTKPDAYQAGKVYVLPKHLDEKVARLHLKKVGAMLTELTDEQAAYIGVSKNGPYKPDTYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOY_LYSSH
Sequence: MLKQQSTLSLVMIAMFAALTAVGAFIKIPLPLVPFTLQIVFVFLAGCLLGGRNGFQSQLVYIGIGLVGLPVFTQGGGITYVLQPTFGYLIGFALAALVIGYMIDRVESPTKKHFIVANIIGLIIIYAVAVPYLYVALNVWLNMKSSWSHVFLVGFVNSIVADFCLAIASALLAERLYKVFRSARAIKLVQIEKENV
What is the function of this protein?
Probable biotin transporter.
What are the official names of this protein?
Probable biotin transporter BioY.
What is the protein family that this protein belongs to?
Belongs to the BioY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS2_PROMP
Sequence: MAVVSLSEMMEAGAHFGHQTRRWNPKMSKYIYCARNGVHIIDLVKTALCMNNAYKWTRNAAKSGKRFLFVGTKKQASDVVAQEAVRCGAAYVNQRWLGGMLTNWTTMKARIERLKDLERMESSGAIAMRPKKEAAVLRRELERLQKYLGGLKGMRRLPDVVVLVDQRRESNAVLEARKLDISLVSMLDTNCDPDLCEVPIPCNDDAVRSVQLILGRLADAINEGRKGSNDQRKN
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: SWIC2_CAEEL
Sequence: MHSQQRPNPQMNRHPYGTPGSAPQMRRPGGFAGQPPQMHGPRMVAPPAAPLPKKKKYADKCIHPKIRELEPDAENYMALLASEQKLDSTLSRKKLDIQEALKRPSKVKKRLRIYISHTFIEEKQPEKDTDEASLPMWELRVEGRLLDEQPPAPAIPGQRPVPKRKFSSFFKSLVIELDKEMYGPDQHLVEWHRTPQTNETDGFQVKRAGDRPVKCRILLLLDNHPAKFKLHPRLAKVLGIATETRPKIIEALWQYIKTHGLQDPQERDIINCDTFLSQCFGVNRMRFMEVPNKLHQLLQQTDPLEFNHIIQRPKEGQEQVSTCYDIDVEMEDPVKQFMHTFVHSPGLANDIQTLDQKCYDIIEQINELKTRRDFYARFYTEPAEFIKSWVMSQNSDLKTMNELSGDLEAERFAESYVRPETEEGVQRYMFQKVNQKRHELEQSLGVRSN
What is the function of this protein?
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).  Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner (By similarity).  Probably regulates vulva development through the let-60/Ras pathway (PubMed:26739451).  Involved in nuclear reassembly after mitosis and recruitment of nuclear envelope protein, mel-28, to the nuclear periphery in the early embryo and in the adult germline (PubMed:26739451).  Involved in gonadogenesis (PubMed:26739451, PubMed:24402584).
What are the official names of this protein?
SWI/SNF chromatin-remodeling accessory subunit 2.
What is the protein family that this protein belongs to?
Belongs to the SMARCD family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Chromosome. Nucleus envelope. Note=Localizes to mitotic chromosomes in the early embryo.
Protein: ISK1_STRCA
Sequence: EPDSAADTGTEAACSNYDLKKGCAKIFDPVCGTDNILYSNECLLCFQNLQRKTNVRIKRRGTCQEPSPR
What is the function of this protein?
This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas.
What are the official names of this protein?
Pancreatic secretory trypsin inhibitor, Serine protease inhibitor Kazal-type 1.
What are the subcellular locations of this protein?
Secreted.
Protein: I13R1_MOUSE
Sequence: MARPALLGELLVLLLWTATVGQVAAATEVQPPVTNLSVSVENLCTIIWTWSPPEGASPNCTLRYFSHFDDQQDKKIAPETHRKEELPLDEKICLQVGSQCSANESEKPSPLVKKCISPPEGDPESAVTELKCIWHNLSYMKCSWLPGRNTSPDTHYTLYYWYSSLEKSRQCENIYREGQHIACSFKLTKVEPSFEHQNVQIMVKDNAGKIRPSCKIVSLTSYVKPDPPHIKHLLLKNGALLVQWKNPQNFRSRCLTYEVEVNNTQTDRHNILEVEEDKCQNSESDRNMEGTSCFQLPGVLADAVYTVRVRVKTNKLCFDDNKLWSDWSEAQSIGKEQNSTFYTTMLLTIPVFVAVAVIILLFYLKRLKIIIFPPIPDPGKIFKEMFGDQNDDTLHWKKYDIYEKQSKEETDSVVLIENLKKAAP
What is the function of this protein?
Binds with low affinity to interleukin-13 (IL13).  Together with IL4RA can form a functional receptor for IL13.  Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity (By similarity).
What are the official names of this protein?
Interleukin-13 receptor subunit alpha-1, IL-13 receptor subunit alpha-1, IL-13R subunit alpha-1, IL-13R-alpha-1, IL-13RA1, Interleukin-13-binding protein, Novel cytokine receptor 4, NR4.
What is the protein family that this protein belongs to?
Belongs to the type I cytokine receptor family. Type 5 subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: FTHS2_DESHY
Sequence: MAFKSDIEIAQESTMLPVAELAEKLNIAEEYVESYGKYKAKIDYNLLKEKGNTPDGKLILVTAINPTPAGEGKTTTTVGLGDALTHLGKKVVIALREPSLGPVFGVKGGAAGGGYAQVVPMEDINLHFTGDLHAIGAANNLIAALLDNHIYQGNALDIDVRRITWKRCMDMNDRQLRYINDGLGGKANGMPREDGFDITVASEIMAILCLSSDLDDLKQRVERIIVGYNRKGEPVTAGQLKAQGAVAALLKDALKPNLVQTLEHTPSFIHGGPFANIAHGCNSVMATKMALKLGDYVVTEAGFGADLGAEKFLDIKCRLSGLEPDAVVIVATVRALKSHGGVAKADLNQENLAALKEGLPNLLKHVENITVNFGLPAVVAINRFPTDTLAEVQLVEEECKKLGVNVALSEVWEKGGAGGVELAEEVLKLMDSPKNFTFAYDIDLGLKEKITAIATKIYGADGVDFIGSSTKDIEGIESIGYRNIPVCMAKTQYSLSDDQKKLGRPTGFRISIRSVKVSAGAGFAVALTGDIMTMPGLPKVPAAESIDVDNTGRISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 2, Formyltetrahydrofolate synthetase 2, FHS 2, FTHFS 2.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: ANMK_METNO
Sequence: MRAIGLMSGTSLDGIDVALIESDGETVRVRRGHNGRIGPLGPTGYRAYSDEDRALLRRALAEAEAIAVRTDRPGCLREAEERVTRLHAEAVENFLTENGLTPADIDLIGFHGQTVIHRPGQGLTVQIGDGARLSRHLGIPVVSDFRQADVAAGGQGAPLVPIFHRALARASGFEGSLAILNIGGVANVTLIAGNGDLLAFDTGPGNALIDDWMSERASRPFDARGSTAAAGRPDEALLAWLLVHPYFTRRPPKSLDRNSFSHRLVGPLSTEDGAATLTAFTVRAVARALDFASEPPRRWIVAGGGARNDEMLRLLRHHLRAEVTPADEIGWSSAFLEAQAFAHLAVRAWNGLPITFPSTTGVSAPMTGGVTARP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: Y140_RICB8
Sequence: MNDKIFYNLSGKTLVSTPYVITKGIYHKSLIYMLSHTEEGAIGLMFNRLVNHIDLKSFFKIKNDEIVNPVMVPIYLGGPVEHEKGFFLHSTDYNKNLLLDFHNDLAVSSNLEISEDIAFGKGPKNSLLIVGYTGWKAGQLEKELEENLWLVMDCDKEFIFADNPENKWHNALKHLGIDEAHFSSQVGSA
What are the official names of this protein?
UPF0301 protein A1I_00140.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: ALR_ACICJ
Sequence: MNHPTLTIDPGAVAANWQALAARHTGEVAGVVKADAYGLGAALIAPALAAAGCRSFFVATLDEALSLRALLPAARIGVLNGCPPGEEGTMRARELRPVLGSLAACARWRGAAGDDKAPPSFLHLDTGMNRLGLDRDEAAHLIAHPTLLDGLGLTHVMTHLVAAEEPDASANAAQRERFAAFAARFPWLRTSLANSSGLFLGPGFGSDLARPGYALYGGNPTPTAANPMRPAIALAAPILQIRAIASGETVGYNGTWRAARPSRIATIGVGYADGLPRSLSNRLTARWQGKIIPVAGRLSMDLTTFDVTDHPDIAPGDVIELIGPGHDIDAFAAEAGTIGYEILTSLGPRYRRVVKSV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: UD18_RAT
Sequence: MAPSGCPPSLPLCVCLFLASGFAQAGRLLVVPMDGSHWFTMQMIVEKLSHRGHEVVVVIPEVSWHMGKSLNFTVKLLLVLNTLEDLNYHFKFFAHNQWKTQEVGMFSLLKHSGKGFFELLFSHCRSLFKDKKLVEYLKQSSFDAVFLDPFDVCGLILAKYFSLPSVVFSGGIFCHYLDEGAQCPSPPSYVPRILSKFTDTMTFKERVWNHLSYMKERAFCPYFFKTAVEIASEVLQTPVTMRDLFSPVSIWMFRTDFVLEFPRPMMPNMVYIGGINCHQGKPLSKEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIAEALGRIPQTLLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHKSKTH
What is the function of this protein?
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile.  Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds.  Catalyzes the glucuronidation of endogenous steroid hormones such as androgens and estrogens.  Produces dihydrotestosterone (DHT) diglucuronide from the DHT after two subsequent glucoronidation steps.  Also catalyzes of the glucuronidation the isoflavones genistein, daidzein, glycitein, formononetin, biochanin A and prunetin, which are phytoestrogens with anticancer and cardiovascular properties.  Involved in the glucuronidation of the AGTR1 angiotensin receptor antagonist caderastan, a drug which can inhibit the effect of angiotensin II.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A8, UGT1A8, A3, UDP-glucuronosyltransferase 1-8, UDPGT 1-8, UGT1*8, UGT1-08, UGT1.8.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: NADE_HELAH
Sequence: MQKHYHKLISYLCDFLEKETQKRGFKKVVYGLSGGLDSAVVGVLSQKVFKENAHALLMPSLVSMPESKSDALDLCETFSIPYTEYSIAPYDAIFCSYFKDASLTRKGNFCSRLRMAFLYDYSLKSNSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELAQHLNIPKKILDKPPSADLFVGQSDEKDLGYPYSVIDPLLKDIEALFRTKPIHLETLTQLGYDETLVKNTISRIQKNAFKLELPTIAKRFDPK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: UNG_TOLAT
Sequence: MQTWSDVLGQEKKQAYFQETMDFVRREREAGKIVYPPAADVFNAFKYTEFADVKVVILGQDPYHGPNQAHGLCFSVLPGVAVPPSLVNIYKELHRDIPGFEIPSHGYLLSWAQQGVLLLNTVLTVEAGKAHSHASSGWEHFTDRVIAALNEHREGLVFLLWGNHAQKKGQYIDRQRHHVLMAPHPSPLSAHRGFLGCGHFSQTNQFLTDADKQPINWQIAPIA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1216_PYRHO
Sequence: MRRISPTRFLLYIVLIFLAAWYLLPIWSAITTSTKTGEQVALTTPVQFVFPPTFDPYREAFRELKRPILNSLIFTTFATIFSTILGSIAGFTIAKLVRGRVSRQLLALISFGIFLPYQSILIPLVKIISSLGLYNRILGLILTHTAYGIPITTLLFTNYYYEIPDELVEAAKIDGADPWKIYTKVILPLSKAPFVVTGIYQFTNIWNDYLFGVVLTRGEEAMPATVKLANLKGSFVANWNIQMAGALIVALPTLLIMIALGKYLIRGYTSGALKG
What is the function of this protein?
Probably part of a binding-protein-dependent transport system PH1214/15/16.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable ABC transporter permease protein PH1216.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSAC_PELHO
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLWHETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: URED_PSE14
Sequence: MNLPANTALFTPSWHAELELGYGRFDDCTRPTQRRHKGPLRVQKHLYAEGPQVCQHIIVHPPGGIAGGDRLDISATVGADAWAQLTSPGAAKWYRAASPAFQQLELHVQPGATLEWLPQETIVFSNAQAELTTRIELHGDAKLCYWDVVALGRPASGERFEQGHFQSHLDIRRDGTLLWHERQRIIGGDGLLDSPIGLDGKTVFATLLLTGEVSSDLLEACRSLSMPNPVRGDLTQLPGLVVARCLADEALHARAWLIQIWKYLRPALLGRQAVTPRIWNT
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_CORJK
Sequence: MAKKKVTGLIKLQIQAGQATPAPPVGPALGAHGVNIVEFTKAYNAATEAQRGNIVPVEITVYEDRSFDFKLKTPPAAKLLLKAAGIQKGSGVPHTDKVGSVTWDQCKEIATTKKEDLNANDIEAGAAIIAGTARSMGITVKDAPQK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.