PharMolix/UniProtQA huggingface dataset:
Protein: KDPA_BACAA
Sequence: MIWVAVVITMLLFILVAKPTGIYLEKAFQGSKKLDKVFGPFEKLIFKITGVKEYNQTWKQYALSLVLLNGFMIVVVYFIFRLQGVLPLNPAHIEGMEPTLAFNTAISFMADTNLQHYSGENGLSYLSQLIGITFLMFAAPATTLALVMAFIRGLAGKELGNFFIDFTRALTRVFLPIAFMAALVFVALGVPQTLDGAVTAQTIDGAKQSILRGPVASFVAIKELGNNGGGFFGANSTHPFENPGQMSNILQMMLMMLLPTALPFTYGRMVGNKKQGRILFVSLFMVFLLGFITITTSELNGNPALNAMGIEHVQGSTEGKEVRFGTVFSSLYATVTTAAETGAVNTMHDTLTPIGGLVPLVNMMLNTVYGGVGAGFVNIIMYAIIAVFISGLMVGRTPEFLGKKIEGKEMKLIAVTILFHPLLILGFSALALSTSLGTDAISHSGFHGLTQVVYEYTSSAANNGSGFEGLGDNTPFWNITTGLVMFLGRYFSLITMLAVAASLKEKTVVPETVGTFRTDNGLFGGIFIGTIVIVGALTFFPMLVLGPIAEFLTLK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL21_STAES
Sequence: MFAIIETGGKQIKVEEGQEIYVEKLNANEGDSFTFDKVLFVGGDSVKVGAPTVEGASVTATVNKQGRGKKITVFTYKRRKDSKRKKGHRQPYTKLTIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: S10AA_XENLA
Sequence: MVAPSELEHSMEKMLLTFHKFAGEKNYMNRDDLQKLLDSEFSEFLKNQNDPMTVDKIMKDLDDCRKGQVNFRSYCSLIAGLLIACNEYYVKHMKKR
What is the function of this protein?
Because p10 induces the dimerization of annexin II (p36), it may function as a regulator of protein phosphorylation in that the p36 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
What are the official names of this protein?
Protein S100-A10, Calpactin I light chain, Calpactin-1 light chain, Cellular ligand of annexin II, S100 calcium-binding protein A10, p10 protein, p11.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: Y1084_AQUAE
Sequence: MNLPDGTQLVVGRQLAKVKSNQNWIRIPEYKVRGNKVIISHLWVGSINMPRRPFWSFRELWEKHLGRKDAINVWSRIRSYNTQVLLKILELLEKEPETQAKKLVKRATMHQLRNIAESFEEL
What are the official names of this protein?
Uncharacterized protein aq_1084.
Protein: THIM_ECOUT
Sequence: MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMSAAVEQATRSQTPWTLDPVAVGALDYRRRFCVELLSHKPTAIRGNASEIMALAGVANGGRGVDTTDAAANAIPAAQTLARETGAIVVVTGEVDYVTDGHRIIGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTLENIASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: YCF4_RHDSA
Sequence: MQTRYDLILGSRRFSNYLWTLISFSGGIGFLLAGLSSYLGVQLLPFGNTETIVFIPQGIVMTFYGTIGILLSLFLLLNISLNVGGGYNSYDKSTGAIQIFRLGFPGKRRKILLQYKIQEIKSIKLSIAEGLNPKREIYLQTKDQRQIPLTRVGEPLLLSQIEEEAVELANFLNIPLEGL
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: COX7C_PANTR
Sequence: MLGQSIRRFTTSVVRRSHYEEGPGKNLPFSVENKWSLLAKMCLYFGSAFATPFLVVRHQLLKT
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7C, mitochondrial, Cytochrome c oxidase polypeptide VIIc.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIc family.
Protein: SIX3_MOUSE
Sequence: MVFRSPLDLYSSHFLLPNFADSHHCSLLLASSGGGSGASGGGGGAGGGGGGNRAGGGGAGGAGGGSGGGGSRAPPEELSMFQLPTLNFSPEQVASVCETLEETGDIERLGRFLWSLPVAPGACEAINKHESILRARAVVAFHTGNFRDLYHILENHKFTKESHGKLQAMWLEAHYQEAEKLRGRPLGPVDKYRVRKKFPLPRTIWDGEQKTHCFKERTRSLLREWYLQDPYPNPSKKRELAQATGLTPTQVGNWFKNRRQRDRAAAAKNRLQHQAIGPSGMRSLAEPGCPTHGSAESPSTAASPTTSVSSLTERADTGTSILSVTSSDSECDV
What is the function of this protein?
Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes.  During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon (PubMed:18094027).  Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression (PubMed:18775421).  In addition, Six3 activity is required for the formation of the telencephalon.  During postnatal stages of brain development is necessary for ependymal cell maturation by promoting the maturation of radial glia into ependymal cells through regulation of neuroblast proliferation and migration (PubMed:22071110).  Acts on the proliferation and differentiation of neural progenitor cells through activating transcription of CCND1 AND CCND2 (PubMed:17576749).  During early lens formation plays a role in lens induction and specification by activating directly PAX6 in the presumptive lens ectoderm (PubMed:17066077).  In turn PAX6 activates SIX3 resulting in activation of PDGFRA and CCND1 promoting cell proliferation (PubMed:12072567).  Also is required for the neuroretina development by directly suppressing WNT8B expression in the anterior neural plate territory (PubMed:20890044).  Its action during retina development and lens morphogenesis is TLE5 and TLE4-dependent manner.  Furthermore, during eye development regulates several genes expression.  Before and during early lens development represses the CRYGF promoter by binding a SIX repressor element (PubMed:11139622).  Directly activates RHO transcription, or cooperates with CRX or NRL (PubMed:17666527).  Six3 functions also in the formation of the proximodistal axis of the optic cup (PubMed:12163408), and promotes the formation of optic vesicles-like structures (PubMed:11458394).  During pituitary development, acts in parallel or alternatively with HESX1 to control cell proliferation through Wnt/beta-catenin pathway (PubMed:18694563).  Plays a role in eye development by suppressing WNT1 expression and in dorsal-ventral patterning by repressing BMP signaling pathway (By similarity).
What are the official names of this protein?
Homeobox protein SIX3, Sine oculis homeobox homolog 3.
What is the protein family that this protein belongs to?
Belongs to the SIX/Sine oculis homeobox family.
Protein: Y3276_BREBN
Sequence: MDWISIILLVLLALGVIGNNATVSIAVAILLLMRLLSLERYFPLLEQHGLQLGIIILTIGIMTPLASGKINPSSFLEIFTNWHSLLAVAVGMFVAYLAGKGTVLMSQNPLIVTGLLLGTIAGVTFFRGVAVGPLIAAGILAFILQFLPK
What are the official names of this protein?
UPF0756 membrane protein BBR47_32760.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CLN5_DICDI
Sequence: MKRTIIILLFVSLFVTFVLSQIPDNDPELCQQRIQREDCPQTPVPWGTFNDNDEIEVYYMQAPVFEAVFGNFFGKLGGYHSAIGFYDLTTGLNYTAEYDAFFEVGNGTLPNIINVDGKDELLWCNAGILCTVPYINETYWDKNIYSTASKTYMGTINGTQLNQYIEWMQQYNISNPVYQTWDVWNNYGQDLFVPSTTCDDFTQQSIEHLGSIGINYNCSTVFKRDYINLFTEKPQPIDFTEHYDDIFKFYEAVLEIKEGSIAQIIERILSIIGLKKYIYVQGEYYLLELNYPFMNAKYDYITLPGCPANGIDYENGNFIHLN
What are the official names of this protein?
Ceroid-lipofuscinosis neuronal protein 5 homolog, Protein CLN5.
What is the protein family that this protein belongs to?
Belongs to the CLN5 family.
Protein: PSAC_PROMT
Sequence: MSHAVKIYDTCIGCTQCVRACPLDVLEMVPWDGCKASQIASSPRTEDCVGCKRCETACPTDFLSIRVYLGDETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: Y181_RUMCH
Sequence: MSGHSKWANIKRQKGAADAVRGKIFTKLGREIQIAVRMGGADPSSNSKLKDVIAKCKANNMPNDNIQRSIKRASGETDGSNYEEITYEGYGPGGVAVICECTTDNRNRTAGDLRHYFDKFGGNLGQSGCVSYMFNKKGVIVIEKNDKVNEETLMMEALDAGAEDFDSDDNCYEIITDPADFSTVREALEAKGYEFIEAEVSMIPTTTTKLTDPEQIKFMDKLIEALEDLDDVSNVYHSWEQDEENEEE
What are the official names of this protein?
Probable transcriptional regulatory protein Ccel_0181.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPA_YERPB
Sequence: MSAQPVDIQVFGRSLRVNCPPEQQDALNMAAEDLSQRLQDLKVRTRVNNTEQLVFIAALNVCHELAQERLKTRDYASNMEQRIRMLQQTIEQALLEQGRISDRQDTQFE
What is the function of this protein?
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring.  It is recruited early at mid-cell but it is not essential for cell division.
What are the official names of this protein?
Cell division protein ZapA, Z ring-associated protein ZapA.
What is the protein family that this protein belongs to?
Belongs to the ZapA family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at mid-cell.
Protein: DAPEL_STRPS
Sequence: MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQIRTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTIALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLKVGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVNPIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFDMEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDGVMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: IAA16_ORYSJ
Sequence: MAWNGRFGEDGEEERSLELSLALPGYFSSSGLQGNTSTAADGAKGNDGFKASRPAAPVVGWPPVRSFRRNLASSSSSSKPPRGGRDAAAAATGGKVARFVKVNMDGVPIGRKVDLAAHGGYGELSAAVDRLFRGLLAAQRDPTMATAAAAAAAGESCTGEEEAIAGLLDGGSGEYTLVYEDDEGDQMLVGDVPWNMFIAAARRLRVLRSSDLNASTIRAGSRKRAAAE
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA16, Indoleacetic acid-induced protein 16.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYH_SALCH
Sequence: MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGAEVFGLQGPDIDAELIMLTARWWRALGIAEHVSLELNSIGSLEARANYRDALVAFLEQHQETLDEDCKRRMYTNPLRVLDSKNPDVQALLNDASALGDYLDDDSREHFAGLCKLLDAAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFIASPVVDIYLVAAGAQTQSAAMTLAERLRDEMPGVKLMTNHGGGNFKKQFARADKWGARIALVLGESEVADGTVVVKDLRSGEQTAVAQDSVAAHLRTLLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_SALCH
Sequence: MSNIIKQLEQEQMKQNVPSFRPGDTVEVKVWVVEGTKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSIAVKRRGAVRKAKLYYLRERTGKAARIKERLN
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: PG157_VACCC
Sequence: MEDLNEANFSHLLINLSNNKDIDAQYASTLSVVHELLSAINFKIFNINKKSKKNSKSIEQHPVVHHAASAGREFNRR
What is the function of this protein?
Required for the association between the dense viroplasm and the viral membranes to form the mature virion (MV).
What are the official names of this protein?
Protein OPG157.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG157 family.
Protein: RS16_METC4
Sequence: MSLKIRLTRGGAKKRPYYRIVIADARAPRDGRFIDKVGAYDPMKAKDDPARIVLDNEKIQSWLAKGAQPTDRVLRFLDAAGLAKRPTRNNPQKAEPGEKAKERAAKRAEKAAAPAEDAAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: RL24_RHIME
Sequence: MQKIRKGDKVVVLTGKDKGRTGEVIQVMPKEDRALVRGVNVVKRHQRQTQNQEAGIITKEASIHLSNIAIADPKDGKPTRVGFKIDGDKKVRVAKRSGDVIDG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: TRMD_STRU0
Sequence: MKIDILTLFPEMFAPLESSIVGKAVEKGLLDIRYHNFRDNAEKARHVDDEPYGGGQGMLLRAQPIYDTIDKIDANNPRVILLDPAGKTFNQSYAEELAQEDELIFICGHYEGYDERIKQLVTDEISLGDFVLTGGELAAMTMVDATVRLIPNVIGKEASHQDDSFSSGLLEYPQYTRPYDFRGMTVPDVLMSGHHENIRRWRLEESLRKTYLRRPDLLEKYPLNQEESDLLAKIKEEM
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_CHLSC
Sequence: MKNITDSFVSVGYWSSAGSFGFNTDILATNPINLSVVLGVLIFFGKGVLSDLLDNRKQRILSTIRNSEELRGGAIEQLEKARARLRKVEMEADEFRVNGYSEIERERVNLINATYENLERLEIYKNETIHFEQQRAINQVRQRVFQQALQGALGTLNSCLNSELHLRTISANIGMFGAMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SFI5_SEGFL
Sequence: KECMVDGTVCYIHNHNDCCGSCLCPNGPLARPWEMLVGNCKCGPKA
What is the function of this protein?
Insecticidal toxin.  It inhibits insect voltage-gated sodium channels (Nav) by partially blocking the channel pore in DUM neurons from the American cockroach, not by acting as a gating modifier.  The inhibition is only partially reversible after prolonged washout.  In vivo, the toxin causes flaccid paralysis followed by death when injected into Heliothis virescens larvae.  It also causes uncoordinated movements followed by full paralysis to sheep blowflies (Lucilia cuprina).  When the toxin is fused to snowdrop lectin, it is orally active against larvae of the tomato moth (Laconobia oleracea), the rice brown planthopper (Nilaparvata lugens), and the peach-potato aphid (Myzus persicae).
What are the official names of this protein?
Mu-segestritoxin-Sf1e, Mu-SGTX-Sf1e, Toxin SFI5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 16 (SFI) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FGF12_RAT
Sequence: MAAAIASSLIRQKRQARESNSDRVSASKRRSSPSKDGRSLCERHVLGVFSKVRFCSGRKRPVRRRPEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST
What is the function of this protein?
Involved in nervous system development and function.  Promote neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation.
What are the official names of this protein?
Fibroblast growth factor 12, FGF-12, Fibroblast growth factor homologous factor 1, FHF-1.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PCRB_BACVZ
Sequence: MYDVNEWKHVFKLDPNKDLPDEQLERLCESGTDAIVIGGSDNITEDNVLRLMSKVRRFLVPCVLEVSTIDSIVPGFDLYFIPSVLNSKKADWIVGMHHQAMKEYGELMSMEEIVTEGYCIVNPDCKAAALTEADTHIETEDILAYARVAEHLLHLPIFYLEYSGMLADIEMVEKTKAVLDKSVLFYGGGIKDAETAERFGRHADVIVVGNAVYEDFDQALKTVAAVKTK
What is the function of this protein?
Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP).  This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales.
What are the official names of this protein?
Heptaprenylglyceryl phosphate synthase, HepGP synthase, Glycerol-1-phosphate heptaprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the GGGP/HepGP synthase family. Group I subfamily.
Protein: AHLLM_RHIRD
Sequence: MTDIRLYMLQSGTLKCKVHNIKMNQGNGADYEIPVPFFLITHPGGHTVIDGGNAIEVATDPRGHWGGICDVYWPVLDKDQGCVDQIKALGFDPADVKYVVQSHLHLDHTGAIGRFPNATHIVQRSEYEYAFTPDWFAGGGYIRKDFDKPGLKWQFLNGTQDDYYDVYGDGTLTTIFTPGHAPGHQSLLVRLPNSKPLLLTIDAAYTLDHWEEKALPGFLASTVDTVRSVQKLRTYAEKHDATVVTGHDPDAWANFKKAPEFYA
What are the official names of this protein?
N-acyl homoserine lactonase AttM, AHL-lactonase AttM.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: TATA_MYCUA
Sequence: MGSLSPWHWAILAVVVIVLFGAKKLPDAARSLGKSMRIFKSEMREMQSETKAEPSAIETNTANPTPVQSQRIDPAAATGQDQTEARPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: RL6_YERPS
Sequence: MSRVAKAPVVIPAGVEVKLNGQVISIKGKNGELTRTVHSAVEVKQEENTLTFAPREGAVDGWAQAGTTRALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLALGFSHPVDHELPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CLAH_PASFU
Sequence: MATATTTTATESPSNSGRRQARYLCLTILGYRKPGMSEEDYRNHMVNVSAPLTKDLMVKYGVKRWTQIHNQSETKALMSQLFDPQMCNLADYDCFSQVVFENIEDYKRMKQDPWYKKHLVGDHENFADTKRSQMTIGWVEEFVRDGQVVEGFKG
What is the function of this protein?
Decarboxylase involved in the biosynthesis of the bianthraquinone cladofulvin, a conidial pigment not required for virulence but that plays a role in fitness and resistance to environmental stresses including UV light and low-temperature stress (PubMed:27274078).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) claG.  The atrochrysone carboxyl ACP thioesterase claF then breaks the thioester bond and releases the atrochrysone carboxylic acid from claG (PubMed:27274078).  This compound is decarboxylated by claH to yield emodin, which is further converted to chrysophanol hydroquinone by the reductase claC and the dehydratase claB (PubMed:27274078).  The cytochrome monooxygenase P450 claM then catalyzes the dimerization of nataloe-emodin to cladofulvin (PubMed:27274078).
What are the official names of this protein?
Decarboxylase claH, Cladofulvin biosynthesis protein H.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: EID2_BOVIN
Sequence: MSELPADQGVPPAGAANDNGDVRQAEVGGRRREPAPAQPVAARDRPMAAAVEGSMASPVEGPVPEAREGPMAASREGLGAAAREARMAEVARLLAEPAEEEGPEGRPRSRPGNGPGLAALPYLRLRHPLGVLGINYQQFLRHYLEHYPIAPGRIQELEGRRRRFVEACRAREAAFDAEYQRNPQRMDFDILTFSITLTASEIINPLIEELGCDKFISRE
What is the function of this protein?
Interacts with EP300 and acts as a repressor of MYOD-dependent transcription and muscle differentiation.  Inhibits EP300 histone acetyltransferase activity.  Acts as a repressor of TGFB/SMAD transcriptional responses.  May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex (By similarity).
What are the official names of this protein?
EP300-interacting inhibitor of differentiation 2, EID-2, CREBBP/EP300 inhibitor 2, EID-1-like inhibitor of differentiation 2.
What are the subcellular locations of this protein?
Nucleus.