PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_STREM
Sequence: MTAMTIKDLKVRLEAVSSLSDPFFEELKADKRLGVQKAVSSRKRALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPIVAACVILPKGCTIKGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMIAAINQLKGSVSKPDYLLIDAMTLEVPIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAFPGYGFAKNAGYGTKEHLQGLHQYGITPIHRQSFEPIKSMTLR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_STRA3
Sequence: MSRKPFIAGNWKMNKNPEEAKAFIEAVASKLPSSELVEAGIAAPALTLSTVLEAAKGSELKIAAQNSYFENSGAFTGENSPKVLAEMGTDYVVIGHSERRDYFHETDQDINKKAKAIFANGLTPIICCGESLETYEAGKAVEFVGAQVSAALAGLSEEQVSSLVIAYEPIWAIGTGKSATQDDAQNMCKAVRDVVAADFGQAVADKVRVQYGGSVKPENVAEYMACPDVDGALVGGASLEAESFLALLDFVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSPA_HALH5
Sequence: MNHRYLPMTTDDRQEMLQAIGVDSIEELFSDIPQDIRFKGKLNIPNALKEPELIRYFQQLANENVHLKDKASFLGAGVYDHYIPSIVDHVISRSEFYTAYTPYQPEISQGELQAIFEFQTMICELTGMEVANSSMYDGPTALAEAAMMSCGHTKKKKILVSKAVHPEARDVLMTNAYGQRLEVVEIDTNNGVTDVEHLKALYDEETACVIVQHPNFFGRLEPLAEIESVSHQGKATFVVSSNPLALGLLKPPGAFGADVVVGDAQPFGIPTQYGGPHCGYFATTKKLMRKVPGRLVGQTTDDQGQRGFVLTLQAREQHIRREKATSNICSNQALNALAAAVAMATIGKRGVKEMALQNVQKAAYAKSQLKANGVEIVAEGPCFNEFIIKLSSPLHEVEEALLAKGFIAGYDLGKVYPELEGHMLVAVTEVRTKEEIDQFAKEVGMFA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 1, Glycine cleavage system P-protein subunit 1, Glycine decarboxylase subunit 1, Glycine dehydrogenase (aminomethyl-transferring) subunit 1.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. N-terminal subunit subfamily.
Protein: T178B_DANRE
Sequence: MAAGKLLLYAGLSLSLCALGMLAVAICSDHWYETDARRYRERCRSFSSRRKDPGFIYIPNNSLPLRASRSRLDRWEEKLLLARNRRQLFAMSAADECSKRYNSTNMGLWSKCHRLGFDQEIEDLIRNGSIARCSYIKYHYSSATIPKDLSYNITKTIRQDEWHSLHLRRMTAGFMGMAVAIILFGWIIGMLGCCWDRGLMQYVAGLLFLMGGTFCIISLCTCVAGINFELSRYPRYIYGLPDDISHGYGWSMFCAWGGLGLSLIAGFFCTLAPSVQPIPRSTCPKSRQENGTVC
What are the official names of this protein?
Transmembrane protein 178B.
What is the protein family that this protein belongs to?
Belongs to the TMEM178 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SSRP_ACIB3
Sequence: MAKATVVKKHNGGTIAQNKRARHDYFIEEKFEAGMSLLGWEVKSLRAGRMSLTESYVIFKNGEAFLFGAQIQPLLSASTHIVPEATRTRKLLLSRRELEKLMGAVNQKGYSCVPLACYWKGHLVKLEIALVKGKQLHDKRATEKERDWQRDKARIFHK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: Y04C_BPT4
Sequence: MNPESKLSQRIAEERAKFFQNMKHNGIEDEVFLNWFWNNKYAACEGALSLSVAMMYEGWKGAKKFSLRASAFLDNKILT
What are the official names of this protein?
Uncharacterized 9.2 kDa protein in Gp55-nrdG intergenic region.
Protein: TTC5_RAT
Sequence: MMADEEEEAKQVLQKLQELVDQLYCFRDSYFETHSVEDAGQKQQDVQEEMEKTLRQMEEVLGSVQVEAQALMLKGKALNVTPDYSPEAEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVAAAHTCFSGALTHCKNKVSLQNLSMVLRQLQTDSGDEHSRHVMDSVRQAKLAVQMDVLDGRSWYILGNAYLSLYFNTGQNPKISQQALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALEGFSQAATLDPAWPEPQQREQQLLEFLSRLTNLLASKGKTKPKKLQSMLGNLRPAHLGPCGDGRYQSATGQKVTLQLKPLSTLQPGVNSGTVVLGKVVFSLTTEEKVPFTFGLVDSDGPCYAVMVYNVVQSWGVLIGDSVAIPEPNLRHHQIQHKGKDYSFSSVRVETPLLLVVNGKPQNSSSQASATVASRPQCE
What is the function of this protein?
Cofactor involved in the regulation of various cellular mechanisms such as actin regulation, autophagy, chromatin regulation and DNA repair.  In physiological conditions, interacts with cofactor JMY in the cytoplasm which prevents JMY's actin nucleation activity and ability to activate the Arp2/3 complex.  Acts as a negative regulator of nutrient stress-induced autophagy by inhibiting JMY's interaction with MAP1LC3B, thereby preventing autophagosome formation (By similarity).  Involves in tubulin autoregulation by promoting its degradation in response to excess soluble tubulin.  To do so, associates with the active ribosome near the ribosome exit tunnel and with nascent tubulin polypeptides early during their translation, triggering tubulin mRNA-targeted degradation (By similarity).  Following DNA damage, phosphorylated by DNA damage responsive protein kinases ATM and CHEK2, leading to its nuclear accumulation and stability.  Nuclear TTC5/STRAP promotes the assembly of a stress-responsive p53/TP53 coactivator complex, which includes the coactivators JMY and p300, thereby increasing p53/TP53-dependent transcription and apoptosis.  Also recruits arginine methyltransferase PRMT5 to p53/TP53 when DNA is damaged, allowing PRMT5 to methylate p53/TP53.  In DNA stress conditions, also prevents p53/TP53 degradation by E3 ubiquitin ligase MDM2.  Upon heat-shock stress, forms a chromatin-associated complex with heat-shock factor 1 HSF1 and p300/EP300 to stimulate heat-shock-responsive transcription, thereby increasing cell survival.  Mitochondrial TTC5/STRAP interacts with ATP synthase subunit beta ATP5F1B which decreased ATP synthase activity and lowers mitochondrial ATP production, thereby regulating cellular respiration and mitochondrial-dependent apoptosis.  Mitochondrial TTC5/STRAP also regulates p53/TP53-mediated apoptosis (By similarity).
What are the official names of this protein?
Tetratricopeptide repeat protein 5, TPR repeat protein 5, Stress-responsive activator of p300, Protein Strap.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasmic vesicle. Mitochondrion matrix. Note=Phosphorylation at Ser-203 results in nuclear localization, while unphosphorylated protein localizes to the cytoplasm. Nuclear localization may be necessary for DNA damage- dependent stabilization of the protein.
Protein: Y6410_MYCS2
Sequence: MQVTSVGHAGFLIESRAGSILCDPWVNPAYFASWFPFPDNSQLDWDALGDVDYLYVSHLHKDHFDPEHLRRYVNKDAVVLLPDYPVPDLRRELEKLGFHNFFETTDSVKHTVSGPKGDLDVMIIALRAPADGPIGDSGLVVSDRVTTVFNMNDARPVDLDVLHTDFGQIDVHMLQYSGAIWYPMVYDMPARAKEAFGIQKRQRQMDRCRQYIAQVGATWVVPSAGPPCFLDPELRDLNDDHGDPANIFPDQMVFLEQLRIHGHDGGLLMIPGSTADFTGSTLNSLTHPVDDPESIFTTGKAAYIEDYAQRMAPVLAAEKARWAPSAGEPMLEALRALFEPIMTQTDQICDGIGYPVELRLTGRDHNETVVLDFPKRVVREPIPDEKFRYGFEIPAALVRTVLRDEEPDWVNTIFLSTRFRAWRVGGYNEYLYTFFKCLTDERIAYADGWFAEAHDDSSSITLDGFQIQRRCPHLKADLSKFGVVEGNTLTCNLHGWQWNLENGRCLTTKGHELRCQKL
What are the official names of this protein?
Putative Rieske 2Fe-2S iron-sulfur protein MSMEG_6410/MSMEI_6242.
Protein: CSC1_DANRE
Sequence: MAFESWPAGGVRPVEELDVRSFLMEENSTAERCYRSHSRSSVLQGLPFGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKNDSLTSLFYGEQSEKEKTPSDSSPSDSETKDMGFCSWLTSLYHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLGDNPENFGRTTVVNVPAQNIFLWLHSIFALLYFVITVLCMAHHSSRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMKGRLYFTTKAQKNGRIMIKTHPCAQIFCCDICGFEKVDAEQYYSELEEKLTDEFNAEKNWISMKRLGIAFVTFRDERMTAVIVKDYSRARCRHKPQQSSITTVVRSHQWDVSYAPAPNDIIWENLSVCGPRWWLRCILLNILLFLLLFFLTTPAIIVNTMDKFNVTRPVESLRNPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQCVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLNQRIHAAAISQVVVAPILCMFWLLFFSVLRLGPVQPITLFTFITLLCSIAFSCFGFCMKKLRADRSTSYQMSDQTTEGGFSDAERSTISTTATANLFIASVLLEPELGLTPMPSPAHQSYGTMVNSQSSVRDAEEDEEKDLEETLETELKDDLLMDSPVAFQ
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel (By similarity).  Required for the functional integrity of the kidney glomerular filtration barrier (PubMed:30900988).
What are the official names of this protein?
Calcium permeable stress-gated cation channel 1, Transmembrane protein 63c.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DNLJ_BRASB
Sequence: MPKTAKPKKPVDVAELTKAQAKVEWKRLALELEVHDRLYYQDDAPKISDAEYDELRRRFNAIETRFPELVSSESPSQKVGASPSGRFKKVRHAVPMLSLDNAFAEEDVRDFVGRIARFLKLADDRIDFSAEPKIDGLSMSLRYEGGELVTAATRGDGAEGEDVTANIRTLKDVPQKLHGRNWPDVCEVRGEVYMTKQAFLALNERQKEAGDTIFANPRNSAAGSLRQKDPAITASRPLGFFAYAWGEISGTPPAETQTGMIKWFEQCGFTTNPLTRLCHSVEELIAFHRSIEEQRAELDYDIDGVVYKVDRIDWQERLGFVSRTPRWAIAHKFPAERAMTVLKDIEIQVGRTGSLTPVGKLEPVGVGGVIVQNVTLHNEDYIKGIGNKGEVLREGRDIRIGDTVVIQRAGDVIPQVVDVVIDKRPAQARPFHLPKTCPCPLHTDVVREETATGEEGSRARCTGEFACPYQKIEHLKLFASRRAFDIDGLGEKQIAFFFEQGWVKEPADIFTLQKRNAGLKLEEIEGYGETSVRNLFNAIDARREIALERFIYALGMRHVGETTALALARGYGSWDAFHEACLKVAAGDEEAIAEMDALDQIGDTVIKSVAAYFAEDHNRGIVERLTQEVKILDAEKPKRHSPIATKTVVFTGTLEKMTRDEAKATAERLGAKVSGSVSKKTDYVVAGPGAGSKLKEAQKHGVQVLTEDEWLQLIAE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SECA_ECOLI
Sequence: MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ
What is the function of this protein?
Required for protein export, interacts with the SecYEG preprotein conducting channel.  SecA has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: MD22B_ARATH
Sequence: MNKGGGSGGGSGGGSGPTAAAAAAALQKQKALLQRVETDITSVVDNFTQIVNVSRVSDPPVKNSQETYMMEMRASRMVQAADSLLKLVSELKQTAIFSGFASLNDHVEQRIEEFDQEAEKTNRLLARIADDASANLKELESHYYSSAQRLTLDI
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 22b.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 22 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RSMA_METM7
Sequence: MRQSKKLGQCFLKDKNFVKKAINRAELTDKDIVLEVGLGEGALTKELAKIAKKVYVIELDERLKPFADEITSEFENVEIIWSDALKVDLKTLGFNKIVANLPYQISSPITFKFLEEDFEVAVLMYQYEFAKRMAGKPDTKEYSRLSVAVQYNADVEFICKVPPSAFSPKPDVNSAIVKLTKREPKYHVKDEEFFKKVLKAIFQHRNRTIKRALIDSSHEIGIERNILKEILEKIENKFEFTERVFKTPPEKIGYLSNLLYDEI
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCKA_PORG3
Sequence: MSKLDLTKYGILNATEIIHNPSYEFLFEEETKAGLEGFEKGQLTELGAVNVMTGVYTGRSPKDKFFVMDDTTKNTIWWTSDEYKNDNKPVTPEAWKSIKKLAVEQLSGKRLFVVDTFCGANESSRLKIRFIMEVAWQAHFVKNMFIRPTEEELANYGEPDFVVMTASKAKVENYKELGLNSETAVVFNLTEKVQVILNTWYGGEMKKGMFSYMNYLLPLRGMASMHCSANTSMDEKETAIFFGLSGTGKTTLSTDPKRKLIGDDEHGWDKDGIFNFEGGCYAKVINLSRENEPDIYNAIRRNALLENVTVDAAGKIDFGDKSVTENTRVSYPIYHIENIVKPVSKAGHAKKVIFLSADAFGVLPPVSILTPEQTKYYFLSGFTAKLAGTERGITEPTPTFSACFGAAFLSLHPTKYAEELVKKMEMVGATAYLVNTGWNGTGKRISIKDTRGIIDAILDGSIDKAPTKAIPFFDFKVPTALPGVDPNILDPRDTYADAAEWTKKAKDLAERFIKNFVKFTGNDAGKALVAAGPKL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDAD_CHLL2
Sequence: MSFVPTKVFFTKGVGRHKEYLSSFELALRDAKIEKCNLVTVSSIFPPKCERISVEEGLKLLSPGQITFAVMARNATNEYNRLISASVGVAIPADDTQYGYLSEHHPYGESDEQCGEYAEDLAATMLATTLGIEFDPNKDWDEREGIYKMSGKIINSYNITQSAEGENGLWTTVISCAVLLP
What are the official names of this protein?
Probable pyruvoyl-dependent arginine decarboxylase, PvlArgDC.
What is the protein family that this protein belongs to?
Belongs to the PdaD family.
Protein: RPO6_SULIK
Sequence: MGLERDGILSQDLHFNEVFVSLWQNKLTRYEIARVISARALQLAMGAPALIDINNISLTDVISIAEEEFKRGVLPITIRRRLPNGKIILLSLRKS
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo6, DNA-directed RNA polymerase subunit K.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARSC_MACCJ
Sequence: MEKKTLYFICTGNSCRSQMAEGWGKHILGDTWNVYSAGIETHGVNPKAIEAMREVGIDISHHTSDLIDQDILNNSDLVVTLCSDADNNCPILPPNVKKEHWGFDDPAGKAWSEFQRVRDEIGHAIEQFKLR
What is the function of this protein?
Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)].
What are the official names of this protein?
Arsenate reductase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family. Thioredoxin-coupled ArsC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPK_PSEP1
Sequence: MTDTQDKNYIIALDQGTTSSRAIIFDRDANVVGTSQREFAQHYPQAGWVEHDPMEIFATQSATMVEALAQAGISHAQVAALGITNQRETTVVWDKETGRPVYNAIVWQCRRSTEICAQLKRDGHEGYIRETTGLVTDPYFSGTKLKWILDNVDGARERAERGELLFGTIDTWLIWKFTGGKVHVTDYTNASRTLMFNIHSLQWDDKLLQILGIPRQMLPEVRPSSEVYGHTKSGIAIAGIAGDQQSALFGQMCVEPGQAKNTYGTGCFLLMNTGDQAVKSSHGLLTTIACGPRGEVAYALEGAVFNGGSTVQWLRDELKIVNDALDTEYFASKVKDSNGVYLVPAFTGLGAPYWDPYARGALFGLTRGVKVDHIIRAALESIAYQTRDVLDAMQQDCGQRLSELRVDGGAVANNFLMQFQADILGTCVERPQMRETTALGAAYLAGLACGFWSGLDELRDKAIIEREFSPQLDETQKEKLYAGWKKAVERTRDWEDHEA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: IF6_NATPD
Sequence: MLRAALSGSSYVGVFATATDEYLLVRPDIEESLQSEFETELDVTAVPTTIAGSGTVGSLAVGNENGLLVTERVTDRERDRLETETGLPVVELPGNINAAGNVVLANNEGAFVHPDLSRDALSAIEEALSVPVERGRIADVQTVGTAAVVTDDGVLSHPKTTDEKLDFLEELFGVYADIGTINYGGPLVGSGLVANNTGYIAGEETTGPELGRIEDALGFIQ
What is the function of this protein?
Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
What are the official names of this protein?
Translation initiation factor 6, aIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
Protein: TLP1A_MANZA
Sequence: ATFDIVNQCTFT
What is the function of this protein?
Has weak beta-1,3-glucanase activity with laminarin as substrate.
What are the official names of this protein?
Thaumatin-like protein 1a, Acidic thaumatin-like protein, Beta-1,3-glucanase.
What is the protein family that this protein belongs to?
Belongs to the thaumatin family.
Protein: CCA_BURM7
Sequence: MKIYAVGGAIRDALLGLPVRDRDYVVVGATPEQMAAQRFRPVGKDFPVFLHPDTHEEYALARTERKTAAGYHGFQFYYAPDVTLEQDLVRRDLTINAMAREVSPDGALVGPVVDPFGGQADLRAKLFRHVGDAFVEDPVRILRVARFAARFAEFAVAPDTAALMRAMVDAGEVDALVPERVWQELARGLMEAKPSRMFAVLRECGALARILPEIDALFGVPQRADYHPEVDTGVHVMMVIDHAAKQGYSLPVRFAALTHDLGKATTPADVLPRHIGHEGRSVDLLKPLCERLRVPNECRDLALVVAREHGNLHRVMEMGAAALVRLLERADALRKPARFAEALQASEADARGRLGLETKPYPQAERLRQALVAARAVDAGAIAQGLAGEPAKIKDAVHRARVRAVAQAVGVAD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: TRPD_CHLAA
Sequence: MNIREAIAAVVARRDLTQAEAASVMEEIMSGTATPAQIGAFLTALHMKGETDAEIAGMAAVMREKATHVYFDGPVIDTCGTGGDGAHTFNISTTAAFVAAGAGLTVAKHGNRAMSSVCGSADVLEGLGVQIELDAEGVARCLREAGIGFMFAPKFHPAMRFAGPVRREIGIRTVFNILGPLTNPARARYQVLGVASAALAEKLAYALSRLDTVHALVVHGDGGVDELTLSGPNLIFDVRAGQAPRQMLVAPEDVGLPRAPQDALRGGDVAYNVAIVRAILSGEEHGPRRDVVLFNAAAAMVAGDLAPDLATGVAMARHSIDSGRALERLNQMIAVSRGE
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SYK_COXB1
Sequence: MELKDQIKEENEQIAQRKLKLKKRREEGQAYPNDFKRDSLAADLHAVYDQFDSGALTAKAIRVKMAGRMMTRRIMGKASFAHIQDMKGRMQIYVTRDSLPQGVYSDFKSWDLGDIVGIEGELFKTKTEELSVKVDQIRLLTKALRPMPDKFHGLHDQEQRFRQRYLDLIVNESSRHLFQTRSQVIAQIRRFLDDRGYIEVETPMMHPLPGGAAARPFETHHNAMNMDLFLRIAPELYLKRLVVGGFEKVYEINRNFRNEGISTRHNPEFTMLEFYQAYATYEDMMMLTESMIRHLAEKIFGVMEIKYQGVRIDLNKPFPRLSLRDAILQFNPGITPDQIDHLETARELAHKYEIATPAHYGLGKIQTELFEKLVEEKLQQPIFITHFPKEVSPLSRANEENDFITDRFEFYVGGREIANGFSELNDPEDQAARFREQLKARNAGDLEAMSFDEDYITALEYGLPPTAGEGIGIDRLVMLFTDNASIRDVILFPLLRSK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURF_MYCTU
Sequence: MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDHAASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP
What is the function of this protein?
Involved in cell wall formation.  Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
What are the official names of this protein?
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase, D-alanyl-D-alanine-adding enzyme, UDP-MurNAc-pentapeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CT52_CONQU
Sequence: MRCVPVFIILLLLSPSAPSVDAHPMTKDDVPQASLHDDAKRTLQVPWMKRGCCAMLTCCVGR
What are the official names of this protein?
Conotoxin Qc5.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin T superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPB_RALSO
Sequence: MSIGTIVQCIGAVVDIQFPRDAMPKVYDALVLQDSGEASFAEKGLSFEVQQQLGDGVVRTIALGSSDGLRRGMPVSNTGAPISVPVGHGTLGRIMDVLGRPIDEAGPIAADEKRAIHQKAPKFDELSPSVDLLETGIKVIDLVCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKQHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVFGQMNEPPGNRLRVALTGLTMAERFRDEGRDILFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFLHLDSTVVLSRDIAALGIYPAVDPLDSTSRQLDPQIVGTEHYEVARRVQQTLQRYKELRDIIAILGMDELSPEDKLAVGRARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMLVDGECDHLPEQAFYMVGSIDEAFEKAKKLQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.