PharMolix/UniProtQA huggingface dataset:
Protein: SC5AB_HUMAN
Sequence: MESGTSSPQPPQLDPLDAFPQKGLEPGDIAVLVLYFLFVLAVGLWSTVKTKRDTVKGYFLAGGDMVWWPVGASLFASNVGSGHFIGLAGSGAATGISVSAYELNGLFSVLMLAWIFLPIYIAGQVTTMPEYLRKRFGGIRIPIILAVLYLFIYIFTKISVDMYAGAIFIQQSLHLDLYLAIVGLLAITAVYTVAGGLAAVIYTDALQTLIMLIGALTLMGYSFAAVGGMEGLKEKYFLALASNRSENSSCGLPREDAFHIFRDPLTSDLPWPGVLFGMSIPSLWYWCTDQVIVQRTLAAKNLSHAKGGALMAAYLKVLPLFIMVFPGMVSRILFPDQVACADPEICQKICSNPSGCSDIAYPKLVLELLPTGLRGLMMAVMVAALMSSLTSIFNSASTIFTMDLWNHLRPRASEKELMIVGRVFVLLLVLVSILWIPVVQASQGGQLFIYIQSISSYLQPPVAVVFIMGCFWKRTNEKGAFWGLISGLLLGLVRLVLDFIYVQPRCDQPDERPVLVKSIHYLYFSMILSTVTLITVSTVSWFTEPPSKEMVSHLTWFTRHDPVVQKEQAPPAAPLSLTLSQNGMPEASSSSSVQFEMVQENTSKTHSCDMTPKQSKVVKAILWLCGIQEKGKEELPARAEAIIVSLEENPLVKTLLDVNLIFCVSCAIFIWGYFA
What is the function of this protein?
Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1 (PubMed:15172003, PubMed:19032932).  Exclusively responsible for apical MI transport and absorption in intestine (By similarity).  Can also transport D-chiro-inositol (DCI) but not L-fucose (PubMed:15172003, PubMed:19032932).  Exhibits stereospecific cotransport of both D-glucose and D-xylose (By similarity).  May induce apoptosis through the TNF-alpha, PDCD1 pathway (PubMed:15172003, PubMed:18069935).  May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney (By similarity).
What are the official names of this protein?
Sodium/myo-inositol cotransporter 2, Na(+)/myo-inositol cotransporter 2, Sodium-dependent glucose cotransporter, Sodium/glucose cotransporter KST1, Sodium/myo-inositol transporter 2, SMIT2, Solute carrier family 5 member 11.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: CAPSD_MBVLF
Sequence: MANRRQSRRRGNKNRNSATVRRAPPNRATQSSSGKVKFVKWIAASPTKLIPHIGENETSYGVLFDITGTTFPELSSLMSRHSRYRVLSLGARIVPYDPNCLGAHSVKVFAESVYDSSATPTVPSVHYLQSNGCRVVPANKQLSSPPSSDVNKYYEICSDDAVIGRIMYAWNGPGLSTARVGFCSFEVYADLEFDGIRE
What is the function of this protein?
Capsid protein self-assembles to form a bacilliform icosahedral capsid with a T=1 symmetry, about 50 nm length and 20 nm large.
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What are the subcellular locations of this protein?
Virion.
Protein: DCD_ECO57
Sequence: MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDESEAFYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RS17_THET8
Sequence: MPKKVLTGVVVSDKMQKTVTVLVERQFPHPLYGKVIKRSKKYLAHDPEEKYKLGDVVEIIESRPISKRKRFRVLRLVESGRMDLVEKYLIRRQNYESLSKRGGKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform and body of the 30S subunit by bringing together and stabilizing interactions between several different RNA helices.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: COX2_CERSI
Sequence: MAYPFQLGFQDATSPIMEELLHFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAIILILIALPSLRILYMMDEINNPSLTVKTMGHQWYWSYEYTDYEDLTFDSYMIPTSDLKPGELRLLEVDNRVVLPMEMTIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLVSTRPGLYYGQCSEICGSNHSFMPIVLELVPLKHFEKWSASML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RL22_RICFE
Sequence: MVQENKNFATAKAKSIRVSPRKLNLVAAFIRNMKVSEALVQLTFSPKKIAKVVKDCLQSAVANAENNLGLDIDRLVITKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKEDN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y3085_RHOPB
Sequence: MSPTRIYVDADACPVKDEIYKVAARHGLPVSVVAGNFIRVPADPSIERIAAGPGMDAADDWIAERAGPGDIVVTSDVPLASRCVKRGAEVLAPNGKPFSEASIGMTLAVRNLMTDLRSAGEVTGGPRGFSPRDRSAFLSALDTAIRRIQRSNKTA
What are the official names of this protein?
UPF0178 protein RPC_3085.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: STK36_PONAB
Sequence: MEKYHVLEMIGEGSFGRVYKGRRKYSAQVVALKFIPKLGRSEKELRNLQREIEIMRGLRHPNIVHMLDSFETDKEVVVVTDYAEGELLQILEDDGKLPEDQVQAIAAQLVSALYYLHSHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPYDHTADLWSVGCILYELAVGTPPFYATSIFQLVSLILKDPVRWPSTISPCFKNFLQGLLTKDPRQRLSWPDLLYHPFIAGHVTIITETAGPDLGTPFTSRLPPELQVLKDKQAHRLSPKGNQSRILTQAYERMAEEAMQKKHQNTGPALEQEDKTSKVAPGTAPLPRLGATPQESSLLAGILASELKSSWAESGTGEAPSAPRENRTTPDCERAFPEERPEVLGQRSTDAVDLEDEEPDSDNEWQHLLETTEPVPIQLKAPLTLLCNPDFCQRIQSQLHEAGGQILKGILEGASHILPAFRVLSSLLSSCSDSVALYSFCREAGLPGLLLSLLRHSQESNSLQQQSWYGTFLQDLMAVIQAYFACTFNLERSQTSDSLQVFQEAANLFLDLLGKLLAQPDDSERTLRRDNLMCFTVLCEAMDGNSRAISKAFYSSLLTTKQVVLDGLLRGLTVPQLPVHTPPGAPQVSQPLREQSEDIPGAISSALAAICTAPVGLPDCWDGKEQVCWHLANQLTEDSSQLRPSLVSGLQHPILCLHLLKVLYSCCLVSERLCRLLGQEPLALESLFMLVQGKVKVVDWEESTEVTLYFLSLLVFRLQNLPCGMEKLGSDVATLFTHSHVASLVSAAACLLGQLGQQGVTFDLQPMEWMAAATHALSAPAEVRLTPPGSCGFYDGLLILLLQLLTEQGKASLIRDMSSSEMWTVLRHRFSMVLRLPKEASAQEGELSLSNPPSPEPDWTLISPQGMAALLSLAMATFAQEPQLCLSCLSQHGSILMSILKHLLCPSFLNQLRQAPHGSEFLPVVVLSVCQLLCFPFALDMDADLLIGVLADLRDSEVAAHLLQVCCYHLPLTQVELPISLLTRLALTDPTSLNQFVNTVAASPRTIISFLSVALLSDQPLLTSDLLSLLAHTARVLSPSHLSFIQELLAGSDESYQSLRSLLGHPENSVRAHTYRLLGHLLQHSMALRGALQSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYQAGPLGPALAAAVPSMTQLLGDPQAGIRRNVASALGNLGLEGLGEELLQCQVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIRQVLVSLGASEKLALLSLGNQLLPHSSPRPASAKHCRKLIHLLRPAHSM
What is the function of this protein?
Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors.  Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization.  GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur.  Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function.  Essential for construction of the central pair apparatus of motile cilia (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase 36, Fused homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Note=Low levels also present in the nucleus.
Protein: JJJ2_CANGA
Sequence: MSINDVTIDTSTYYSILGVPTNASTNEIRKSYMKLAKKLHPDKTKSEHTAELFKLVVDAHSILNNDQLRAEYDKKLILEGRFELHQHGAKQKNKDIRKGYTFKRNSKPYEQQPYGFGVQVPKGPHEESNYEANSNPHNENSSNNDTKMKSTNLHDTLSKDSEDKHGTDDASDIQPPTKSNDIANEVGSKRKSNSKDIHQDHSSNIGLNPLKKKKLEKKAVHATTTESRRYMRKKSEKKATPPIQPLADLQINDDWEKLREVLQRIEKEDSRGGKEFTLDIDVNEQMYNLSMESSDDEHTIPTKKRAKVGSNIQGNSRYFAQTAAYDMNQINANLGTRNTEDDRQASSKISITEIDDILDLLKERVPSPPKLGHLGVQRDQQNRALEYIKYTDELKKRILYVLSNSSTTEAMQHFNRHTQSVLAHKTMELRLCEKLTEIQKCQQGVIEYFSRTALG
What are the official names of this protein?
J protein JJJ2.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: FOLD_THET2
Sequence: MAAQVLSGHEAAEAVYEEIRARLRSLSFTPSLRVIRLGEDPASVAYVRLKDKRARALGYRSQVEVYPEDLPEEALLERIAALNADEEVDGILVQLPLPPHIRTQRVLEAIHPLKDVDGFHPLNVGRLWSGGKGLFPCTPLGVVRLLKHYGVDLRGKEVVVVGRSNIVGKPLAGLLLREDATVTLAHSKTQDLPQVTRRAQVLVVAVGRPHLVRKEWVREGAIVVDVGVNRVEGRLLGDVHPEVAEVASALTPVPGGVGPMTVAMLMGNTLEAALLRRHGASG
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DEF1_GLOVI
Sequence: MHLKRAYPKDCLSGVGSNACRIGDRQSRYPVTIECESTGTSGGGVYEIVKTGDPVLRLTAKPLNSDEIQSEAIQQLIAAMAERMREAPGVGLAAPQVGVSVQLVVIEDRPEYIERLSGAERREREREPVPFHVLINPVLSVEGEESAVFFEGCLSIPGYQGLVARARVVRVEALDERAAPVVIRAHGWYARILQHEIDHLNGLLCVDRMDLQTFSTLENYDRFWRGG
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: BR21_AMOCU
Sequence: MFTMKKSMLVLFFLGTISLSLCEEERNADEDDGEMTEEVKRGILDKLKEFGISAARGVAQSLLNTASCKLAKTC
What is the function of this protein?
Antimicrobial peptide active against a variety of Gram-positive and some Gram-negative bacterial strains.  Has antifungal activity against a slime mold isolate.  Has hemolytic activity against human erythrocytes.
What are the official names of this protein?
Brevinin-2CG1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: CD123_VANPO
Sequence: MNTDYTPLVNVPIKREDIETCRFSNWYPLFKKHCPTAEIIGPLPAEFIEYLEQDGIKIPNENRSFYSEDLTINDDNEYSDWDNEDDDEEEDKVIQQEVKKEIDPLADFPELHRQIKDVITKYGAVAPKMNWSAPKDATWILPNNTMKCNEINEVYLLLNASNYIAHDLQHAFDECEDIEDQKKSSDFELVLRKWFDINPALEFRIFIKDNEILGISQRDLNYYDYLEPLVDKFRDLIEDFIDDEILDRFPLKSFVIDLYIPRPFNKVFLIDINPFARMTDPLMFSWSELLTKNEPVTPIGQEEDYEFRLIKENNVGRFACKEHSENQVPTDIVEASLNPEAIRELTQKWKELLSKQSMEEDSSSDSNEE
What is the function of this protein?
Regulates the cell cycle in a nutrient dependent manner.
What are the official names of this protein?
Cell division cycle protein 123.
What is the protein family that this protein belongs to?
Belongs to the CDC123 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXL11_HUMAN
Sequence: MSVKGMAIALAVILCATVVQGFPMFKRGRCLCIGPGVKAVKVADIEKASIMYPSNNCDKIEVIITLKENKGQRCLNPKSKQARLIIKKVERKNF
What is the function of this protein?
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes.  Induces calcium release in activated T-cells.  Binds to CXCR3.  May play an important role in CNS diseases which involve T-cell recruitment.  May play a role in skin immune responses.
What are the official names of this protein?
C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: ZN608_MOUSE
Sequence: MSVNVSTAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTNTTTNTTKDCGGPASNGTCSTSALADGLKFASVQPSAPQGNSHKETSKSKVKRAKTSKDANKSLPSAALYGIPEISSTGKRQEVQGRPGEATGMNSALGQSVSGGGSSNPNSNGTSTGTSAATAGAGSCGKSKEEKPGKSHSSRGAKRDKDAARSRKEKHDLLQGHQNGGGGQAPSGGHLYGFGTKSNGSGASPFHCGGAGSGSVGAAGEVSKTAPDSTLMGNSMLVKKEEEEEESHRRIKKLKTEKVDPLFTVPAPPPPIASSLAPQIPPSYFPPSSSNIAAPVEQLLVRTRSVGVNTCEVGVVTEPECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESPTSDLEMRGGRGRGKRARSAAAAPGSEVSFTESRGLQSKNRGGANGKGRRGSLNASGRRTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDSKPGKRVRTNSRSTPTTPQGKPETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSEDKISDCEEALSNVALECNESSTSVSSYDQTKAPGSPGAGNPPGTPKGKREHVSNGPGPIIGSKTGKNSGKKRGLNNELNNLPVISNMTAALDICSATDSNLTAEMPKLEAEGLIDKKSLGDKEKGKKANNCKMDKNLSKLKSARPIAPAPAPTPPQLIAIPTAAFTSTTTGTIPGLPSLTTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDRKKKEKRKLKDKEGKETGGPKMDAKLGKLEEAKAASKDLSGHFLKDHLGKSEGLANGLSESQESRMASIKAEADKVYTFTDNAPSPSIGSASRMECSTLVNGQAPMAPLHVLTQNGAESAAAKTSSPAYSDISDAADDGGSDSRSEGMRSKASSPSDTFSNKDGVVKGHPSTSAQPSQLKESHSPYYHGYEPYYSPSYMHPGQVGAPAAGNGGSTQGMKIKKESEEDAEKKDKAEQLESKKVDHTSAPLQPQHQSVITQRHPALAQSLYYGQYAYGLYMDQKSLMATSPAYRQQYEKYYEDQRLAEQKMAQSGRGDCERKAELPLKELGKEDNKQKNMPSATISKAPSTPEPNKNHSKLGPSVPNKTEETGKSQLLSSHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVDPTSRFKQDPESRTWHHYVYQPKYLDQQKPEELDREKKLKEDSPRKTPNKESGVSSLPVSLTNIKEEPKEGKRPDSQSVEENKLKNDDRKTPVNWKDSRGTRVAVSSPMSQHQSYIQYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYGKMSGREEAEKVNTSPSINTKTASEAKALDLLQHHANQYRSKSPAPVEKASTEREREAERERDRHSPFSQRHLHTHHHTHVGMGYPLIPGQYDPFQGLTSAALVASQQVAAQASASGMFPAQRRE
What is the function of this protein?
Transcription factor, which represses ZNF609 transcription.
What are the official names of this protein?
Zinc finger protein 608.
Protein: RL11_AGARV
Sequence: MAKKVEGYIKLQIPAGKATPAPPVGPALGQHGVNIVEFTKQFNAKTADQGDLIIPVVITVYADRSFSFITKTPPAPVLIKKACKIQSGSGEPNKKKVAKITKAQVQEIAELKMPDLNAASLESAMSMIAGTARSMGVEVTE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: UBP47_HUMAN
Sequence: MVPGEENQLVPKEDVFWRCRQNIFDEMKKKFLQIENAAEEPRVLCIIQDTTNSKTVNERITLNLPASTPVRKLFEDVANKVGYINGTFDLVWGNGINTADMAPLDHTSDKSLLDANFEPGKKNFLHLTDKDGEQPQILLEDSSAGEDSVHDRFIGPLPREGSGGSTSDYVSQSYSYSSILNKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLETNSGTEKISKSGLEKNSLIYELFSVMVHSGSAAGGHYYACIKSFSDEQWYSFNDQHVSRITQEDIKKTHGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLEVDEYPEHIKNLVQKERELEEQEKRQREIERNTCKIKLFCLHPTKQVMMENKLEVHKDKTLKEAVEMAYKMMDLEEVIPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMFDLLLETRKPDQVFQSYKPGEVMVKVHVVDLKAESVAAPITVRAYLNQTVTEFKQLISKAIHLPAETMRIVLERCYNDLRLLSVSSKTLKAEGFFRSNKVFVESSETLDYQMAFADSHLWKLLDRHANTIRLFVLLPEQSPVSYSKRTAYQKAGGDSGNVDDDCERVKGPVGSLKSVEAILEESTEKLKSLSLQQQQDGDNGDSSKSTETSDFENIESPLNERDSSASVDNRELEQHIQTSDPENFQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNADNAQIPLANGLDSHSITSSRRTKANEGKKETWDTAEEDSGTDSEYDESGKSRGEMQYMYFKAEPYAADEGSGEGHKWLMVHVDKRITLAAFKQHLEPFVGVLSSHFKVFRVYASNQEFESVRLNETLSSFSDDNKITIRLGRALKKGEYRVKVYQLLVNEQEPCKFLLDAVFAKGMTVRQSKEELIPQLREQCGLELSIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEVLDGVEKMKSMSQLAVLSRRWKPSEMKLDPFQEVVLESSSVDELREKLSEISGIPLDDIEFAKGRGTFPCDISVLDIHQDLDWNPKVSTLNVWPLYICDDGAVIFYRDKTEELMELTDEQRNELMKKESSRLQKTGHRVTYSPRKEKALKIYLDGAPNKDLTQD
What is the function of this protein?
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER).  Acts as a regulator of cell growth and genome integrity.  May also indirectly regulate CDC25A expression at a transcriptional level.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 47, Deubiquitinating enzyme 47, Ubiquitin thioesterase 47, Ubiquitin-specific-processing protease 47.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: CC117_RAT
Sequence: MAALGRPFSGLPLSGSADFLQSPPAFAGRAFPPGAAGHDLAPRPGVRGPPSSPDGRTARGRVSIHCRKKHKRLAEDDECPVRKKRLTEAELGAVADEWVLGTHQGIEGHGVNTCPGGLSVPSILDAVCEEMDQTTGEPQCEVARRRLQEIEDRIIDEDEEVESDRNVSHLPSLVLSDTMKTGLKREFDEVFTKKMIESMSRPSMELVLWKPLPELLSEKPKPSSNPKNYMGESQTKHTATGTAFPQRTEVLLEPQCTDTPLYHSLETAASTEEEMEL
What is the function of this protein?
Facilitates DNA repair, cell cycle progression, and cell proliferation through its interaction with CIAO2B.
What are the official names of this protein?
Coiled-coil domain-containing protein 117.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle. Nucleus. Note=Mitotic spindle.
Protein: FMT_STAAB
Sequence: MTKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMTPPPVKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVDLIVTAAFGQLLPESLLALPKLGAINVHASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDNVGTMHDKLSVLGADLLKETLPSIIEGTNESVPQDDTQATFASNIRREDERISWNKPGRQVFNQIRGLSPWPVAYTTMDDTNLKIYDAELVETNKINEPGTIIETTKKAIIVATNDNEAVAIKDMQLAGKKRMLAANYLSGAQNILVGKKLI
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: ATPL_PASMU
Sequence: METVITTTIIASAILLAVAALGTALGFAILGGKFLESSARQPELASSLQIKMFIVAGLLDAISMIAVGIALLFIFANPFIDLLK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB_THET2
Sequence: MRHLLDFQGWSRTEVESLLDTARVMREVLERPIKKVPALQGFTVATVFFEPSTRTRISFELAARRMSADVVSFAAQTSSLQKGESYKDTLLTLEAMGVDAYVIRADSAGVPHQATRWVKGAVINGGDGRRAHPTQALLDAYTLLEALGTLEGKKVAIVGDILHSRVARSGAELLSLLGAQVFCAGPPSLLPQSLPGAHLTPRLEEALEEADAVMVLRLQKERMEAGLVHLEDYVARYQVTEKRLALAKPQAPLLHPGPMNRDVELEGTLADSARSLVNRQVQNGVAVRMAVLYHLLVGREKA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: IF1_HYDCU
Sequence: MSKQDVIEFDGEVIETLPNTMFKVRLENGHEILAHISGRMRKNYIRILAGDKVKVELTPYDLTKGRITYRGK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_BORGP
Sequence: MDVKTLKGFKDYLPKDSLIRIHIVKQIFSVLNSYNFDLIDTPVLEYSELLLKKSGDESEKQIYRFKDHGGRDVSMRFDLTIPFARFVATNISDLKFPFRRSQFGKVFRGENSQKGRYREFMQFDFDIVGEDGFRADAEILSVVYYGLEEIFLNFIEGINKKFIIHYSHLGILNSFFEKLGIKEESIFILRNIDKIDKIGIDKVKEALLLKIEKEAVDSILSLVNLQGAFKDKIQALKSILGDNESVKRVEDVYRHLSLLKIQDSFNLNLKISGGLDYYTGIVFESEVFGSNMGSVCSGGRYDNLVSSYSSSIQKVSGVGGSFGVDRIKDIIDLEQFSYIKIFVTKARSKVLIVNLDSALQNYYYELATRFRNHDYSKVKNISCEVYFKNKNGKNIKEQIEYALNKEIRFLVFVGQEEYKENKIKVRDLTKKEELLLSFEEVINVIKCNEKLLCTPF
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MQO_PROM1
Sequence: MFNTPTPDSENTYDAILVGAGIMSSTLAVLLHELEPDLRLLVVEKLSSAGLESSCAKNNAGTGHAANCELNYTPIQEDGHLSTNKAFEINKSFEQSLEFWASLAEKGKLIPKTFLNKLPHISLVFGDEDISLLKKRFSKLSSHAAFAEMEFTMDHGELKDWVPLIMDGRQHSEKIAATRIKRGTDIDFGNLTRSYINQIEGAKSIDINYSTNVENLQQDSEGDWYLSLEGAKNNRIVRSKFVFLGAGGGALSLLQKSRIPEGLLYAGFPVSGKWLICDEEKSTKTHNAKVYGKAAVGAPPMSVPHLDTRWIDKKKSLLFGPFAGFSSNFLKYGSKLDLFRSIKTTNLFSMLQAGLDNIDLGKYLLNQLIQTNEDRIDTLKRFLPQVSPNDWKLSTAGQRVQIIKQTSKGGVLKMGTEVVTSSDGSLAALLGASPGASTAVTIMIEVLNRCWLEKMKSSKWKNKMLELFPSIGTDINSDQEALLAIRKRNDFLLKLI
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: RL20_THEAB
Sequence: MRVKNAVNAKKKRRKILKAVKGYHGALSRRYRLAKQAYIKAKKHAYVGRKLKKRDFRKLWITRINIAARNEGLKYNELIHGLKLAGVAINRKMLSELAVNDPESFKEYVNIAKQAIGK
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: YGAP_ECOLI
Sequence: MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLSVLEQSGLPAKLRHEQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKKAGLPVAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSGFFLLSGFVGAGLLFAGISGFCGMARLLDKMPWNQRA
What are the official names of this protein?
Inner membrane protein YgaP.
What is the protein family that this protein belongs to?
To Synechocystis PCC 6803 slr1261.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRH_LACH4
Sequence: MSQVKYKRIILKISGEALAGDKGNGINPTVIGHLAKEIKSVYDLCVGIGIVCGGGNMWRGETGAKLGMERAQADYMGMLATIMNGLALQDGLEKVGVPTRMQTSIEMRQIAEPYIRRRALRHLEKGRVVIFGGGTGNPYFSTDTTAALRAAEIGADVILMAKNGVDGVYSADPKTDPTATKFTELTQLDLISKNLKVMDRTASSLSMDTEIPLIVFNVNTPGNIKKVVVGENIGTVIRGDK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.