PharMolix/UniProtQA huggingface dataset:
Protein: PAP_GEOSE
Sequence: MPYRILFVCTGNTCRSPMAAALLENKQLPGVEVKSAGVFAAEGSEASVHAKMVLKEKGIEAAHRSSQLKKEHIDWATHVLAMTSGHKDMIVERFPEAKDKTFTLKQFVSGTDGDIADPFGGPIEVYRAARDELETLIDRLAEKLQTEQ
What is the function of this protein?
Catalyzes the specific dephosphorylation of phosphoarginine residues in proteins.  Probably counteracts the protein arginine kinase McsB in vivo.  Exhibits almost no activity against pTyr peptides.  Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity.
What are the official names of this protein?
Protein-arginine-phosphatase, PAP, Phosphoarginine phosphatase.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: SSTT_ACIBS
Sequence: MLEFFSRLSLVTKIIIAIILGIGVALLFPTVTPYLSLFGELFIKALKSVAPILAFVLVLSSIANFQVGHSANLRPVLLLYVVGMLLAAFSAVIASLSFPSTLYLNTVSHNNLQAPGSLADILKNLLLSFIANPVQAISEANFIGILAWAIGLGLAMRHSSDTTKQVMQDVSHAVSAIIHKVIAFAPVGIFGLVAVTFADAGLATLESYAQLLAVLLGTMLFVALVINPILVGLTIRGNPYPLVFKCLKESGITAFFTRSSAANIPVNLDLAERLGVNPSTASVSIPLGATVNLAGAAVTITVLTLATVHTLGIHVDLATMIILSVVATVSACGASGVAGGSLLLIPVACSLFGISSEIAMQVVAVGMIISVLQDSTETALNSSTDVLFTAAVDIRSRQNS
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ETTA_HAEIN
Sequence: MSSQFVYTMHRVGKVVPPKRHILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPQPGIKIGYLPQEPKLEPQQTVREAVEEAVSEVKNALTRLDEVYALYADPDADFDKLAAEQANLEAIIQAHDGHNLDNQLERAADALRLPDWDAKIEHLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDYEGTVVAITHDRYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKEKRLEQEQATENARQKSIAKELEWVRQNPKGRQAKSKARMARFDELNSGEYQKRNETNELFIPPGPRLGDKVIEVQNLTKSYGDRTLIDDLSFSIPKGAIVGIIGANGAGKSTLFRMLSGQEQPDSGSVTMGETVVLASVDQFRDSMDDKKTVWEEVSNGQDILTIGNFEIPSRAYVGRFNFKGVDQQKRVGELSGGERGRLHLAKLLQRGGNVLLLDEPTNDLDVETLRALENAILEFPGCAMVISHDRWFLDRIATHILDYGDEGKVTFYEGNFSDYEEWKKKTLGDAATQPHRIKYKRIAK
What is the function of this protein?
A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio.  Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation.  ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
What are the official names of this protein?
Energy-dependent translational throttle protein EttA, Translational regulatory factor EttA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with ribosomes and polysomes.
Protein: DDL_ANAMF
Sequence: MPVSLARNAGMLSVAVLCGGSSPEREVSLAGGKRVADALGRLGYNATVLDLNRESVGQLLAMAPDLVYNALHGVQGEDGCVSGLLDILGLACTHSHVAASSVGMDKVLTKHVLKSLGIDFPKFDVLTKEELLSAKEVLPYPFVIKPVRGGSTIGVHAIFSKSEYLDLSAHADTLEDRMIVEEYVSGQEVQTAVFLGRAIGTMELLFEGRIYSYDAKYVEGLCEHIFPANLPYDIYNLTLEWALKLHQCLGCKTLSRVDFRYDVANKALKLLEINTHPGMTVSSTLPEVLWLRCGLNFDHVVDLIVQDALGIDDSRRAYIDELMGKTVSREPSHV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET_ECHTE
Sequence: MKAPAALAPGILVLLLTLVQKGGGECREALAKSEMNVNMRYRLPNFTADTPIQNVVVHEGHVFLGAINSIYVLRERDLQQVSEYKTGPVWEHPDCLPCQACGLAGGQWRENVNMALLVETYYDDQLISCGSVHRGTCQRHVLPRDNPADIQAEVHCMHSPRADEDEASQCPDCVVSALGTKVLLAEKQRFVNFFVGNTLNGSSLPGHALHSISVRRIKETQDGFKFLTDKSYIDVLPEFQASYPIKYIHAFESNRFIYFLTVQRETLDSPSFHTRIIRFCSADSGLRSYMEMPLECILTEKRRKRALRSEVFNVLQAAYVGKPGAQLAKQIGASAHDDILYGVFSQSRPDSAEPTDRSALCAFPVKYVDEFFHRIVNKNNVRCLQHFYGPNHLHCFNRTLLRNSSGCEVRSDEYRTEFTTALQRIDLSAGHFSQVLLTSISTFIKGDLTIANLGTSEGRFMQVVVSRSGSWTPHVDFRLDSHAVSPEVIVEHPVNQNGYTLVVTGKKITKIPLDGLGCEHFQSCSQCLSAPPFVQCGWCHDKCARAEDCPNGTWTQEICLPTIYEVFPASAPLEGGTTLTVCGWDFGFRRNNKSDFKRTRVLIGNESCPLTLSESTPNMLKCTVGPAMSEHSNLSIIISNVRGTAPQYRTFSYVDPEITSISPSYGPKAGGTLVTLTGKYLNSGNSRHISIGGKTCTLKSVSDSVLECYTPAQSISADFPVKLKIDLANREAYSFSYQENPLVVEIHPTKSFVSGGSTITVVGKNLNSVSVPRMIINVHEVEMNFTVACQQRSNSELICCTTPSLQQLDLQLPLKATAFFMLDGIHSRDFDLIYVPNPVFKLFEKPVMISMGNENVLEIKGNDIDPEAVKGEVLKVGNKSCENIHSYPESVLCTVPNDLLKLNSELNIEWKQAVSSTVLGKVIVQPDQNFTGLIVGVVSISVILLSSLGLFLWLKKRKQIKDLGSELVCYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGSCRQVQYPLPDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVQHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDNDDRKIHCAVKSLNRITDIGEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHSPTVKDLIGFGLQVAKGMKYLASKKFVHRDLAARNCMLDGKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITVYLLQGRRLLQPEYCPDPLYEVMLKCWHPKAEMRPSFTELVSRISAIFSTFIGEHYVHVNATYVNVKCVAPYPSLLSSHDTVDGEVDT
What is the function of this protein?
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand.  Regulates many physiological processes including proliferation, scattering, morphogenesis and survival.  Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules.  Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.  Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC.  The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects.  During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation.  In adults, participates in wound healing as well as organ regeneration and tissue remodeling.  Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
What are the official names of this protein?
Hepatocyte growth factor receptor, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: SP5G_ARCFU
Sequence: MAEITEVRIYKSKGNGSVKAYASVSFDNEFVVKGLKVVEGEKGLWVSMPSRRMKDGSFQDVFHPVSREARDKIVDAVLKAYQEQE
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: EFP_PSELT
Sequence: MVEVGDLKKGMVIMVNGEPHRVVDVSKHHMAMGRGIIRTKLKSVVTGFVKDVNFSSGERVEEANLSFRQAQFLYSDGAHYHFMALDDYEQYILSEEDLQDAKWYLIENLELSLVFLEDKPIGVQLPNVVTLKVVETEPSFKGDTVSGGGKPAVLETGLKINVPFFVETGEFIKVDTRTGEYVERA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCSR2_PAESO
Sequence: MSNLYESIRKYKCGYIEEILNILDMFDPLLNKFQRNSCYEDMKSELSLFMFNLIDNFPLEKDCFKEDKFIINYIYKALKNKFIQVNKLHQKIKSCESNIDIVALNNCDYSNLLSFVIFEDIIKDLTQNEKNIIRKIYLDRLRESEISRELNISRQAVNKTHLRALEKLKKLIN
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (Probable).  Transcriptional regulator specifically required to activate expression of the toxin gene locus, composed of tcsL, tcsH and tcdE/utxA (PubMed:23873908).
What are the official names of this protein?
RNA polymerase sigma factor TcsR.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: ARGB_ACTPJ
Sequence: MLQNEVENFTNLLEQATVYLAPYQEKIIVVKYGGNAMINEDLKKLVMQDILLLNQLGVKVVLVHGGGPEISQGVKLLGKEPQFINGLRVTDQDTINVVLQMLAGKVNKSLVALLKGKGVGLCGIDANMLQCEKLQAEVDYGFVGEIVKVNTQLLELALSANLIPVISTVGVDDQGVAYNINADTVASEIAMALGAAKLVSMTDIAGLLRDRFDESTLIPEVEVSEVQGLIDQGIIAGGMIPKIACCTDFINAGGIEANIIDGRVPHAILVSLFGGKNGTLFYKK
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_SHIB3
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDHD_LISIN
Sequence: MDIVSRQKVRRFEAGTFQEIESSVATEYPLTIYVNDQELVTIVCTPEHLEDLVVGFLTSEGIVRGPGDIDSVDIIEATGHAKVSANFVNKFNAKYRGKRYITSCCGKSRENFYFQSDASLVNVKQNSNLKLTTDRIFRLMEKFEQNSATFHQTGGVHNAALCSSAEIIYSRMDIGRHNALDKIYGRALKDGTATDDKAIIFSGRISSEILVKTAKLGCGIILSRSAPTELAINMAEELNITTVGFIRGDRLNVYSGFERIT
What is the function of this protein?
Required for formate dehydrogenase (FDH) activity.  Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.
What are the official names of this protein?
Sulfur carrier protein FdhD.
What is the protein family that this protein belongs to?
Belongs to the FdhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YH21A_YEAST
Sequence: MPYHYLFLALFTYLATSNVVSGSTQACLPVGPRKNGMNVNFYKYSLLDSTTYSYPQYMTSGYASNWN
What are the official names of this protein?
Uncharacterized protein YHR212W-A.
What is the protein family that this protein belongs to?
Belongs to the flocculin family.
Protein: EMTA_ESCF3
Sequence: MKLRWFAFLVVLLAGCATKRDYENPPWNAKVPVQRAMQWMPISQKAGAAWNVDPQLITAIIAIESGGNPNAVSKSNAVGLMQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIKDPQVLQYALVVSYANGAGALLRTFSSDRKKAITKINDLSADEFFDHVAKNHPAPQAPRYIWKLQRALDEM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: COAX_CHLL3
Sequence: MEQMAHPSSTPLLVAEIGNTTAMFAVFSGTDPIDSLQVATAALSSPEAVGELLQPLLARHSLAADAVISSVVPRAGEAAGRWLLDILPGRVLAVDSTLNLPFRISYDPPSALGADRLSLCARCCMLEEEAAVIALDIGTAITFDVLSADRSYLGGLIMPGLELMASALHERTAQLPRVEVSRPERLMGLSTADCIRSGVVWGCVLQVEGLVRKIRGWLRSEHGEGYARVVATGGRAPLIVSMMEMPPLLDPHAVSRGARYLFELNRITVS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_STAAR
Sequence: MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQFGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELDGLNERGIPTSNLRISNRAQVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLLKSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVLFEGAQGVMLDIDHGTYPFVTSSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGPFPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVLTGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPENARKYLERISELCNVQISIFSVGPDREQTNLLKELW
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_LEPBA
Sequence: MAEETNQSLEDQNVQVEEGQTISDEAIEQAVEGAEKELDNAKKEIESLKDSWLRERAEFQNYKRRTANDLLNARKESIKKFAEGLTGALDNLERVSNVPNQTPEVVAFVEGIKMVQKEFYSVLEKEGIKRLDPKGQPFDPMLMEAIASEESAEFTEETVVETYQAGYYHEEGESKQSIRPARVKVGKPQS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELG1_SCHPO
Sequence: MQIVGYLSADSQSNPDLKSENEAKEEKPIGRRHTMSPVPATSENKYFGKSPLSGSRKPRRSRSLHKERSYMRKFFDMDMEESKDFENDQSLLVTLKVSTSLGQKIENILHPKLSNDTNSTAFPPAKSSGEASDTNILVENINSQETVNSSPLVSELHYSNLADSPSNLRNTVTSMHPFFMSKSVKKNSEIKFVSEERGGTKPERLLDPLWPTPDSQSMLEYAGSIEPSVFWFPKKHLEEAILEETSHLSFKEVLSSTTANMITPLAEKNKTEVLQVTPSKLHTFALESLCFSPAPFIQKVLSRLLPSDPNVEMPMIPQILEKGLWVSKYAPSKTQDCCAFSQCLSKIADWLRSCRLTKPESSSVPPSSSISRSSTIHSCTSSKRNEDSLSESDFEPDIIEEEDDSDEFNPSVSRKKAKLTSSQFSNWMLVTGVTGIGKTSCLYAICRELNFEVVEIHPGMRRSGKELLERIGELTQSHIVDKSRLNNTPDILILLEEVDILFQDDRGFWQAVSTLIEKSKRPVVMTCNETDFLPSAFLQEDHIVQFQSISSALLTDYISSVLYADRCIISRNVVESISYRYGSDLRGILMQLNFWSLVNFPSLPSKDKQDDSHEPFIEATISAFDEGVGVYNPRIQTSEDLLQTYSEEQMGDIGLLFMPNLVNWRKVCVPKSEMEEKEAIMEKLIYSHQYADSLSYVDYRFSSQPTIYETYELMNDSASFEDMSLECRDNCANAFQDNLVGFPTISNPFHANAPPEPHELKLQYHSFCFINNLFSKSSLKAISSNDSIVPKALNNRELQLSALASTIGYKLDPDDVYNILSFLSFANSQVTSYTPPNSIDRPNDILILEVAPFVRCMRRYDRIRLNSYKLLLSSKGRSASHISRRGAASILRSAGYNYGRLQYLEGSDRILSTWFSTTLD
What is the function of this protein?
Involved in the negative control of telomere length and in telomeric silencing through a replication-mediated pathway.  May have a role in Okazaki fragment maturation.  Required for S-phase progression.  An RFC-like complex (elg1-RFC) is formed where elg1 replaces rfc1 in the RFC complex.  This complex appears to have a role in DNA replication, replication fork re-start, recombination and repair.
What are the official names of this protein?
Telomere length regulation protein elg1, Telomere elongation suppressor elg1.
What is the protein family that this protein belongs to?
Belongs to the ELG1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: M310_ARATH
Sequence: MALPVYAMSCFRLSKLLCKKLTSAMTEFWWSSCENKRKISWVAWQKLCKSKEDDGGLGFRDLGWFNQALLAKQSFRIIHQPHTLLSRLLRSRYFPHSSMMECSVGTRPSYAWRSIIHGRELLSRGLLRTIGDGIHTKVWLDRWIMDETPLPPLN
What are the official names of this protein?
Uncharacterized mitochondrial protein AtMg00310, ORF154.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: DNLJ_GLUOX
Sequence: MTTAPVSAAERHAALEADLAQWDEAYHGRDEPEVSDAVYDAARRELLALEEAYPDLRSQEGASQRVGATPDSAFGKYRHLVPMLSLDNVFDPEGFDGFVSRVGRFLGLDEDGLQALQFVAEPKIDGLSISLTYEHGHFVRGTTRGDGIEGEDVTANLLTLKDIPRELPGEAPERVEIRGEVFLSKSSFLTLNEQQVARGAKPFANPRNAAAGSLRQLDAEITRSRPLSLFAYAQGYTSSPVATTHWDYLEKLRSWGFTVNPLSQMIAHARDIPAYVEKLARERSELDYDIDGIVFKLDDLSLQDRLGFAGRAPRWAIAWKFPAEQAITRLREIEIQVGRTGALTPVAHLEPVNVGGVIVSRATLHNEDEIARKDVRVGDLVRLQRAGDVIPQILGPVPSEEPRSEPFVYPDHCPVCGSLAERVHGEAVRRCTGGLTCEAQIVERLIHMVSRNAFDIDGLGERSIREFYDAGYIRRPGDIFRLRQHEEALLQRDGWGRLSVDNLFRAIEDRRTIPLSRLIFGLGIRRIGERNAQLLARHYQTFENWRTAMLAARPDSEERASLGAIMGVGDAIADELSAFFSESHNIETLDDLALELKDIIAEEAPSEGHLSGKVIVFTGTLTTMSRPEAKAIAERLGAQVTDSVSKKTSLVVLGEKAGSKAKKAAELGIETVDESGWRVLAGL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: YCIB_BUCA5
Sequence: MKQILNILPMFIFFIFYKFYDIFIASGSLIVISGLICIIHWILYNEIDKISLFSFLSVFFFGSLTIFFHNSQFIKWKITIIYIIFSLVLLISQFFTRKPMIQRFLEKDIKISNIYWRKINFIWSLFFLFCAILNIYIAYYFSETIWVNFKVFGFTSLTFFLILITSIYINCKISKNK
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: APT_MYCSK
Sequence: MTDISKVIASLMREVPDFPEPGIQFKDLTPLLADAEGLMAVTDALAATAEGADLVAGIDARGFLLGAAVALRLGTGVLAVRKGGKLPPPVHSQTYNLEYGSATLEIPADGLDIAGRSVVIIDDVLATGGTVAATHRLLTSGGATVLHAAVVLELTALGGREVVQPLSVSSLYTV
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_FINM2
Sequence: MARQVSLKDTRNIGIMAHIDAGKTTVTERILYYSGKIHKIGDTHDGAAQMDWMVQEQERGITITSAATTCFWKGNRINIIDTPGHVDFTVEVERSLRVLDGSVALFDAKSGVEPQSETVWRQADKYGVPRICFINKMDATGADYFMSVDTIRERLRANAVPIEIPIGAEDKFVGVVDLITMKANIYKNELGTEFTVEEIPSDLVEVAEKYRAELLENIAEHDEELMEKYLEGEELTEEEIKRAIRTATIANAMNPVLCGSAYKNKGVQPLLDAIVDYMPAPIDVPDIKGVDPQTDEPTTRKSSDEEPFAALAFKIATDPYVGKLAFTRVYSGTVESGSYVYNSTKGKRERIGRILMMHANKREEIDKAYAGDIVAIIGLKDTTTGDTLCDMDSEVILENMEFPDPVISVAIEPKTKASQEKMGIALAKLAEEDPTFRTYTDEETGDTIISGMGELHLEIIVDRLLREFKVEANIGNPQVAYRESITQAAEAQGKYVKQSGGRGQYGDCTLRVEPLDNPEESNGIEFVNAIVGGAIPKEYIPSVQAGAEEAAQTGILGGYPMLDMKITLLDGSYHDVDSSEMAYKIAGSMGFRAAVAKAKPILLEPAMKVEITTPDEYLGDVMGDVSSRRGKIDGMNPKNGVHVLDAFIPLAEMFGYATDLRSKTQGRATYSMQFDHYEQVPNSISEEVIGKKNNK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_ECOLI
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RPP5_ARATH
Sequence: MAASSSSGRRRYDVFPSFSGVDVRKTFLSHLIEALDGKSINTFIDHGIERSRTIAPELISAIREARISIVIFSKNYASSTWCLNELVEIHKCFNDLGQMVIPVFYDVDPSEVRKQTGEFGKVFEKTCEVSKDKQPGDQKQRWVQALTDIANIAGEDLLNGPNEAHMVEKISNDVSNKLITRSKCFDDFVGIEAHIEAIKSVLCLESKEARMVGIWGQSGIGKSTIGRALFSQLSIQFPLRAFLTYKSTSGSDVSGMKLSWEKELLSEILGQKDIKIEHFGVVEQRLKHKKVLILLDDVDNLEFLKTLVGKAEWFGSGSRIIVITQDRQFLKAHDIDLVYEVKLPSQGLALTMLCRSAFGKDSPPDDFKELAFEVAKLAGHLPLGLNVLGSSLRRRGKKEWMEMMPRLRNGLNGDIMKTLRVSYDRLHQKDQDMFLCIACLFNGFEVSYVKDLLEDNVGLTMLSEKSLIRITPDGHIEMHNLLEKLGREIDRAKSKGNPGKRQFLTNFEDIHEVVTEKTGTETLLGIRLPFEEYFSTRPLLIDKESFKGMRNLQYLKIGDWSDGGQPQSLVYLPLKLRLLDWDDCPLKSLPSTFKAEYLVNLIMKYSKLEKLWEGTLPLGSLKKMNLLCSKNLKEIPDLSNARNLEELDLEGCESLVTLPSSIQNAIKLRKLHCSGVILIDLKSLEGMCNLEYLSVDCSRVEGTQGIVYFPSKLRLLLWNNCPLKRLHSNFKVEYLVKLRMENSDLEKLWDGTQPLGRLKQMFLRGSKYLKEIPDLSLAINLEEVDICKCESLVTFPSSMQNAIKLIYLDISDCKKLESFPTDLNLESLEYLNLTGCPNLRNFPAIKMGCSDVDFPEGRNEIVVEDCFWNKNLPAGLDYLDCLMRCMPCEFRPEYLVFLNVRCYKHEKLWEGIQSLGSLEEMDLSESENLTEIPDLSKATNLKHLYLNNCKSLVTLPSTIGNLQKLVRLEMKECTGLEVLPTDVNLSSLETLDLSGCSSLRTFPLISKSIKWLYLENTAIEEILDLSKATKLESLILNNCKSLVTLPSTIGNLQNLRRLYMKRCTGLEVLPTDVNLSSLGILDLSGCSSLRTFPLISTNIVWLYLENTAIGEVPCCIEDFTRLRVLLMYCCQRLKNISPNIFRLRSLMFADFTDCRGVIKALSDATVVATMEDSVSCVPLSENIEYTCERFWGELYGDGDWDLGTEYFSFRNCFKLDRDARELILRSCFKPVALPGGEIPKYFTYRAYGDSLTVTLPRSSLSQSFLRFKACLVVDPLSEGKGFYRYLEVNFGFNGKQYQKSFLEDEELEFCKTDHLFFCSFKFESEMTFNDVEFKFCCSNRIKECGVRLMYVSQETEYNQQTTRSKKRMRMTSGTSEEYINLAGDQIVADTGLAALNMELSLGEGEASSSTSLEGEALSVDYMITKEQDEDIPFLDPVSDGTWRSFYSAE
What is the function of this protein?
TIR-NB-LRR receptor-like protein that confers resistance to the pathogen Hyaloperonospora arabidopsis isolate Noco2 (downy mildew disease) (PubMed:9212464).  Confers resistance to H. arabidopsis isolates Emoy2, Emwa1 and Noco2 (PubMed:11846877).
What are the official names of this protein?
Disease resistance protein RPP5, Protein RECOGNITION OF PERONOSPORA PARASITICA 5.