PharMolix/UniProtQA huggingface dataset:
Protein: HBB1_RAT
Sequence: MVHLTDAEKAAVNGLWGKVNPDDVGGEALGRLLVVYPWTQRYFDSFGDLSSASAIMGNPKVKAHGKKVINAFNDGLKHLDNLKGTFAHLSELHCDKLHVDPENFRLLGNMIVIVLGHHLGKEFTPCAQAAFQKVVAGVASALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta-1, Beta-1-globin, Hemoglobin beta chain, major-form, Hemoglobin beta-1 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NFUA_ECOLU
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: YNH9_SCHPO
Sequence: MDFTALFASLNPTFASVSHCGNWIASLSRSGHVLIRNSETLELHHVFLLNAQFIQKVVYLLWKPNLGAEKCHQICVASVDKVFVLDIVQHDYYASIQCDQDPLSSISWSPSGELLLWSSFDSKITVWSLNTQKGYLLPHVKTNVSKVYALHPSMQFCTILSRFNGSDCLQFYQISKKAWILLKECKLPTIDSTGIHWSPDGNWLAVLENVLDAVVYIYHRTGLLFHEYRPNRLIEVGFSDFEWSPFGKYLTLCSYHDSTLHLLETKTFSIVFRLHHCLQYTNTDLEMHIWEEKETIYEQQMTYQKVHKLRTDFPEPSFCSASKIRFNCDETYAATITSKYPNVLWLWNLQNKKLHTVLIQKHHIVYFEWHPGRPDLVVIQTKIRKESKIPSNATFLYFWALSWNTPRVVGVPKKGFNIQKVQWLQPSEFSSRPVIVICGEDAYTVAYIVEDEDESFTEVTQTIISQEVLDNELETTQTISIPS
What are the official names of this protein?
Uncharacterized WD repeat-containing protein C32H8.09.
Protein: Y1643_HAEIN
Sequence: MNTRPFYFGLIFIAIIAVLANYLGSTDFSHHYHISALIIAILLGMAIGNTIYPQFSSQVEKGVLFAKGTLLRAGIVLYGFRLTFGDIADVGLNAVVTDAIMLISTFFLTALLGIRYLKMDKQLVYLTGAGCSICGAAAVMAAEPVTKAESHKVSVAIAVVVIFGTLSIFTYPFFYTWSQHLINAHQFGIYVGSSVHEVAQVYAIGGNIDPIVANTAVITKMLRVMMLAPFLFMLSWLLTRSDGISENTSHKITIPWFAVLFIGVAIFNSFDLLPKELVKLFVEIDSFLLISAMAALGLTTQASAIKKAGLKPLVLGVLIYLWLVIGGFLVNYGISKLI
What are the official names of this protein?
UPF0324 membrane protein HI_1643.
What is the protein family that this protein belongs to?
Belongs to the UPF0324 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CDA1_YEAST
Sequence: MKIFNTIQSVLFAAFFLKQGNCLASNGSTALMGEVDMQTPFPEWLTEFTNLTQWPGIDPPYIPLDYINLTEVPELDRYYPGQCPKISREQCSFDCYNCIDVDDVTSCFKLSQTFDDGPAPATEALLKKLRQRTTFFVLGINTVNYPDIYEHILERGHLIGTHTWSHEFLPSLSNEEIVAQIEWSIWAMNATGKHFPKYFRPPYGAIDNRVRAIVKQFGLTVVLWDLDTFDWKLITNDDFRTEEEILMDINTWKGKRKGLILEHDGARRTVEVAIKINELIGSDQLTIAECIGDTDYIERYD
What is the function of this protein?
Hydrolyzes the N-acetamido groups of N-acetyl-D-glucosamine residues in chitin to form chitosan and acetate (PubMed:9133736).  Chitosan is a component of the spore wall (PubMed:9133736).
What are the official names of this protein?
Chitin deacetylase 1.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide deacetylase family.
What are the subcellular locations of this protein?
Prospore.
Protein: ADP2_MYCGA
Sequence: MKKLIFKLSVGITPLALIGLGSFGLAVSGAKPNNLKPVNQVGEMNSQGQSNLLEKARRWRNSNFTSLSIDGTNPGALVLTGSKSISRIDLYGNVIWTFDPGNTNDLTGKVGFYDANNRLTAFSGDVPFNVSDLSSKTVVEATQDQEDPNVFYLLLIPDAAVQQEQKTKDQVFENYFMSDAPATGDTSAEGSATPAGGGSSSSAAGGGAVAPAAASSTARLVEEGNSAGMGTMTPTASTSETVIDYNSDQNKIPKPKTLLDSSESSESINGGRTYANINTQNNLQGVIVKVNENLFNSENPFAVENMAFIKPKDMVDNYPSTWTQGSANGKMTNVLQFYKHDNPNAVNNRFYRAKYYPKRLETQTTTPLIDSSFSPYEHPEWYEDNQFVMPWMQYITNLGGLYAKDGMVYLFGGNGTWVNNESALSIGVFRTKFENRTAEAPGNTKTVGYPYGILLSAISFDATRNGLALAPASLGQDVGYHFVPRLAVGGVSSPRGANGNIFLGSAITWGTNGGNFLDTKWHSPAVIEDAPTTFVTVNSSGALQNSGNPQPTSTPMPNSNGNESIPYRWTNSYDYNSVRFAALISKPAGGNTKQVESLFTTALKLDTLNSLPNKFTQENNIFFSYAMLDGRQWSLGTRKDSAWLTTNTINNFTYNTQQQLASTVAGENANPRNILNALTTAKGFDRRDIGNVVYTYSNNTNKFTYYYQVGGAITTWPEVQVNYKTSANITYYNLTRTDFGSTTPATQDANTVSSKLNGAYLSSTGDQQGWYNGSIYVKKASFTPSSQGYTWQDFKGLTTTASNAVISNWTKAGYSIRPDDDTVFNVSKIPFEKEITAAVNVRSLDSYYVQLNGETSVNTVARVSPDSSALALNPNRITNPLMNRDNVIGQGAFISRNDIPSSFFENKINDIVTTEADGKEVLDSKYINSIYRYTPPQNNPDIRLRLLVIDRSRATNDFIKLLPQVLVDGEYVAVPQANSVFVSDQEFTGFDALPGYVLPVAISIPIIIIALALALGLGIGIPMSQNRKMLKQGFAISNKKVDILTTAVGSVFKQIINRTSVTNIKKTPQMLQANKKDGASSPSKPSAPAAKKPAGPTKPSAPGAKPTAPAKPKAPAPTKKIE
What is the function of this protein?
Could be involved in cytadherence.
What are the official names of this protein?
Adhesin P1, Adherence protein A, Attachment protein, Cytadhesin P1.
What is the protein family that this protein belongs to?
Belongs to the adhesin P1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: MOAP1_MACFA
Sequence: MTLRLLEDWCRGMDMNPRKALLIAGISQSCSVAEIEEALQAGLAPLGEYRLLGRMFRRDENRKVALVGLTAETSHALVPKEIPGKGGIWRVIFKPPDSDNTFLSRLNEFLAGEGMTVGELTRALAHENGSLDLEQGMIPEMWAPMLAQALEALQPALQCLKYKKLRVFSGREPPEPGEEEFGRWMFHTTQMIKAWQVPDVEKRRRLLESLRGPALDVIRVLKINNPLITVDECLQALEEVFGVTDNPRELQVKYLTTYQKDEEKLSAYVLRLEPLLQKLVQRGAIERDAVNQARLDQVIAGAVHKTIRRELNLPEDGPAPGFLQLLVLIKDYEAAEEEEALLQEVLEGHFT
What is the function of this protein?
Retrotransposon-derived protein that forms virion-like capsids (By similarity).  Acts as an effector of BAX during apoptosis: enriched at outer mitochondria membrane and associates with BAX upon induction of apoptosis, facilitating BAX-dependent mitochondrial outer membrane permeabilization and apoptosis.  Required for death receptor-dependent apoptosis.  When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation.  Also promotes autophagy: promotes phagophore closure via association with ATG8 proteins.  Acts as an inhibitor of the NFE2L2/NRF2 pathway via interaction with SQSTM1: interaction promotes dissociation of SQSTM1 inclusion bodies that sequester KEAP1, relieving inactivation of the BCR(KEAP1) complex (By similarity).
What are the official names of this protein?
Modulator of apoptosis 1, MAP-1.
What is the protein family that this protein belongs to?
Belongs to the PNMA family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Mitochondrion outer membrane. Extracellular vesicle membrane. Note=Forms virion-like extracellular vesicles that are released from cells.
Protein: AMPP3_ASPTN
Sequence: MATVDTILQGKYPAKAHARRVAEYLQAQCPGNPGVIYLESQKTRMIEDNDETMPFRQRRPFFYLSGCLLPEASLVYDVSADKLTLFIPAIDPEDVIWSGLPLSPSEAMELYDVDNVLTTPEVNATLASIASAHNGKAVAYAIQGRTSPETKFEGFQDANFTLLNGWIEQARVVKDAYEIALLRKANDISTKAHIAAIKAAKTATNEREIEGAFIATCIANGAREQSYHPIVACGENGATLHYPKNDAELTDPVTKQRKKNVLIDAGGEYRTYCADITRVIPLGGRFAQETRQIYQIVLQMQLECIAMLKDGVLWDDVHAHAHRVAIKGLLQLGILRGSEDELFEKRVSVAFFPHGLGHYLGMDTHDTGGNPNYGDKDKMFRYLRVRGHLPAGSVITVEPGIYFCRFIIEPYIKSPETSKYIDTDVLERYWSVGGVRIEDNVHVTKDGYENLTTAPKIMEEVESLAL
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase pepP, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: Y2260_LACCB
Sequence: MKFIIAPAKKMIRAQDDFPVQSQPKFRVQAGELLLLMQQLTFSEAQALWHTSDKLTQTAYNQLQQSDLTRQQSPAIFSYSGIQYQYMAPDLLDDAGLVYIQQHLRILSGLYGILRPFDGVVPYRLEMQNHLPLPHHRNLYDFWGNRLYQALARMPGPIINLASDEYAKAIRPYLQAKDQFIDVRFAHRVNGQLKTRATYAKMARGEMIRFAASHRLTKAADLKNFDSPTYRFNAHLSTATQLVFIAK
What are the official names of this protein?
UPF0246 protein LCABL_22600.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: FH12_ORYSJ
Sequence: MALLRRLFYRKPPDRLLEIADRVYVFDCCFSTETMEQFEYKNYLDNIVLQLREQFVDSSLMVFNFRDEGKSLVSGLFSLYGITVKDYPCQYLGCPLLPLEMVLHFLRLSERWLMLEGQQNFLLMHCEKGGWPVLAFMLAGLLLYMKQYNGEERTLVMVYKQAPKELLQMLTTLNPQPSHLRYLQYICKMDDELEWPIQPIPFTLDCVILREVPNFDGVGGCRPIVRVYGQDFLTVDKRCNVMLPPSKPRKHARRYKQQADNISVKLNVGSCVQGDVVLECLHIDDSLEDERLMFRVMFNTYFIQSHILPLNFENIDVSWDAEQRFTKKFKAEVLFSEFDGESDASIEVASDYDDEVEVGSIDVFFEAVEIFSNLDSQEGQRDAEILSITSTECSPRAELMKTAPFSHFDMEIGLGGSQKNKIDGMVLSLEKSDEKCTSAEGDIIQNNITRVVRSSSANTTDGDRDTMNSSCYGGKVDGCIVEKNNSNKEILTDSNEDSGIENVLVKEVIISETNSLKDIQMIKEVIISEVTTSKPVIEVDTIGTELSDVVHNSETITHAEANNEEEVLVTLKQNEGDNLVEECIYYGNSIMIKPEKYRKKEKSIIGSTIGVVPDSTEENSRVGLLLSVKPHLDSTGTYHDLNSPLQKIDLLNVSNTNCVEEQTKGMEASISNSYGQPSNLSSLNLQPQGSSFQANGDPTCANTSTDANESTQLELKRKSFLSLSTSSIFSPLSPRRNLLRSTSTDLSFLSPLQTKSNQHSIPCSSGRDDFASSYGPPPNIPCTSLRTSKVSSLVHPSLRPLRTVSSLSQSSFEEYLDISPPSPTFHEKHQQHFNLDPPSLIPPWQLRLAKTKENEIYPCTLSFLPLSPSNKYAHHPPFPPPPPPPHVLCTQNNSRTQISEYEQGRVEGPCPSSSYGQSILNSHDVSLSLPQKDSSCIAITNGPSSSNYVEEVPMETILNQPTLSIPLEACKDELLHCKENGGIPIPPPPPPLCDHAKKYTRIPLPPPPPEGSHGILATTSTELIDAGPQLPPLSHLEWKRCPHHPPERPHYLPGEVGGAPSPPSPPPPQRENTSVGIQGGIPPLPPPLPPTLGDYGVAPPPPSIGAGAPPPPPPPGGITGVPPPPPIGGLGGHQAPPAPPLPEGIGGVPPPPPVGGLGGPPAPPPPAGFRGGTPPPNAHGGVAPPPPPPRGHGGVGGPPTPPGAPAPPMPPGVPGGPPPPPGGRGLPAPPGGRGVVGHGLTRSLGLNSAATARRSTLKPLHWVKVTRAMHGSLWAEIQKQADANSHSEFDVKELESLFAIAPKTKGGSKSDGASKSLGSKPDKVHLIDLRRANNTEIMLTKIKMPLPDMMSAALALDDSVLDADQLENLIKFCPTKEEMELLKNYTGDKETLGKCEQFFLELMKVPRVESKFRIFAFKIQFQSQIRDVRKNLLTVSSACEELRGSEKLKVIMEKILFLGNKLNQGTPRGQALGFRLDSLLKLTDTRANNSRMTLMHFLCKGLADKSPHLLDFYEEFVNLEAASKLQLKALAEEQQAVVKGLQKVEQELAASESDGPVSEVFRKTLKEFTDASGADVRSLSALYAEVGKSADALAYYFGEDPAKCPFEQVTSTLLNFVGLFRKAHEENIKQIEADKKKAQKEAEKEANQDRTPVKSKDGLVDRSPRSPFK
What are the official names of this protein?
Formin-like protein 12, OsFH12.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-II subfamily.
Protein: FLGH_STRM5
Sequence: MSPLSNFARTALACAVAALLGGCVIAGDVRPYPTMAPIQPIMPPQAQPTAGAIYAAGPTLQLYSDRRARDVGDLLTISLLENTTAQTSANTATNKESNLSLGTPSIFGAPVTLGGKDILSASAKGARDFTGKGNSAQSNRLQGNVTVTVIQRLPNGNLVVQGQKNLRLNQGDELVQVQGIVRPGDISQDNTIPSSRVAEARIVYGGRGPVAQSNAMGWLSRFFNSGLTPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: NU2M_PARHE
Sequence: MKPPILIIIMSTVISGTMIVLTSSHWMLTWIGFEMNMLAVIPILMKKFNPRAMEASTKYFLMQATASMLLMMGITINLLHTGQWTILNNLNPTASTLMTIALAMKLGLAPFHFWVPEVTQGISLSSGMILLTWQKIAPLSVLYQISPNINPKLLLLMAILSVLIGGWGGLNQTQLRKILAYSSIAHMGWMSTILIYNPTMMLLNLIIYIMMTLSTFMLFMHNSTTTTLALSQTWNKMPLITSLILMLMLSLGGLPPLSGFIPKWMIIQELTKNEMIIMPTFLAITALLNLYFYMRLTYATALTMFPSTNNMKMKWQFENTKKTMFLPPLIVMSTMLIPLTPIISILE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MSHR_OVIMO
Sequence: MPALGSQRRLLGSLNCTPPATLPLTLAPNRTGPQCLEVSIPNGLFLSLGLVSLVENVLVVAAIAKNRNLHSPMYYFVCCLAMSDLLVSVSNVLETAVMLLLEAGVLATQAAVVQQLDNVIDVLICSSMVSSLCFLGAIAVDRYISIFYALRYHSVVTLPRAWRIIAAIWVASILTSVLSITYYNHTVVLLCLVGFFIAMLALMAVLYVHMLARACRHARGIARLQKRQRPIHQGFGLKGAATLTILLGVFFLCWGPFFLHLSLIVLCPQHPTCGCIFKNFNLFLALIICNAIVDPLIYAFRSQELRKTLQEVLQCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGK_ANOFW
Sequence: MNKKTVRDIDVKGKRVFCRVDFNVPMQNGVVTDDTRIRAALPTIQYLMEQGAKVILASHLGRPKGKVVEEMRLNAVAERLSELLGKRVVKTDEAYGDTVKAAIAEMNEGDVLLLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTEGIAHHLPAVAGFLMEKEIEVLGKALSNPDRPFTAIIGGAKVKDKIGVIENLLDKVDNLIIGGGLAYTFVKALGHEIGKSLLEEDKIDLAKSFMEKAKEKGVNFYMPVDAVVADDFSNDANKKVVNIDEIPSDWEGLDIGPKTRELYRDVILKSKLVIWNGPMGVFEMDAFAEGTKAVAQALADAKDTYTVIGGGDSAAAVEKFGLANKMDHISTGGGASLEFMEGKQLPGVVALNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_STRS2
Sequence: MYDYIKGILTKITAKYIVVETQGVGYILQVANPYAYSGQVQQEVTVYTHQVIREDAHLLYGFATENEKSVFLSLISVSGIGPTTALAIIAVDDNDGLVRAIEQKNITYLTKFPKIGKKTAQQMILDLEGKFVMSEEAGPVQQVAPSSENIALEEAMEAMEALGYRPAELKKIKKFFEGTNDTAENYIKSALKMLMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: HSL12_DICDI
Sequence: MTLLASISSIGNVKSISKSNNFSSLSNSSLQSSNSIQCGGCGGSPLIGTVGNLVGGVLVGTGIIVGTVVGTVNGVVGGLLSGPNCGCH
What are the official names of this protein?
HssA/B-like protein 12.
What is the protein family that this protein belongs to?
Belongs to the hssA/B family.
Protein: EGFL8_MOUSE
Sequence: MGLWAELCISLRGLSFFLVLMTGEGTRGGSFKESLGVCSKQTLLVPLRYNESYSQPVYKPYLTLCAGRRICSTYRTTYRVAWREVRREVPQTHVVCCQGWKKPHPGALTCDAICSKPCLNGGVCTGPDRCECAPGWGGKHCHVDVDECRASLTLCSHGCLNTLGSFLCSCPHPLVLGLDGRTCAGGPPESPTSASILSVAVREADSEEERALRWEVAELRGRLEKLEQWATQAGAWVRAVLPMPPEELRPEQVAELWGRGDRIESLSDQVLLLEERLGACACEDNSLGPSLRG
What are the official names of this protein?
Epidermal growth factor-like protein 8, EGF-like protein 8.
What are the subcellular locations of this protein?
Secreted.
Protein: YMDB_SALTY
Sequence: MTSRLQVIQGDITQLSVDAIVNAANASLMGGGGVDGAIHRAAGPALLDACKLIRQQQGECQTGHAVITPAGKLSAKAVIHTVGPVWRGGEHQEAELLEEAYRNCLLLAEANHFRSIAFPAISTGVYGYPRAQAAEVAVRTVSDFITRYALPEQVYFVCYDEETARLYARLLTQQGDDPA
What is the function of this protein?
Deacetylates O-acetyl-ADP ribose to yield ADP-ribose and free acetate.  Down-regulates ribonuclease 3 (RNase III) activity.  Acts by interacting directly with the region of the ribonuclease that is required for dimerization/activation.
What are the official names of this protein?
O-acetyl-ADP-ribose deacetylase, Regulator of RNase III activity.
What is the protein family that this protein belongs to?
Belongs to the YmdB family.
Protein: APSI_PECAS
Sequence: MATYNYPEFGAGLWHFANYIDRYAVDGYGPALSTIDQINAAKEVGELSYVDLPYPFTPGVTLSEVKDALKDAGLKAIGITPEIYLQKWSRGAFTNPDPAARAAAFELMHESAGIVRELGANYVKVWPGQDGWDYPFQVSHKNLWKLAVDGMRDLAGANPDVKFAIEYKPREPRVKMTWDSAARTLLGIEDIGLDNVGVLLDFGHALYGGESPADSAQLIIDRGRLFGMDVNDNLRGWDDDLVVGTVHMTEIFEFFYVLKINNWQGVWQLDQFPFRENHVEAAQLSIRFLKHIYRALDKLDIPALQAAQEAQNPLQAQRIVQDALLSSITVSE
What is the function of this protein?
Involved in catabolism of D-apiose.  Catalyzes isomerization of D-apiose to apulose.
What are the official names of this protein?
D-apiose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_PSET1
Sequence: MKESVYHKLEILVERYEEVQALLSDPSVIRDQNRFRALSKEYSDLEEVVKTFLSYQQAQQDVISAEEMLKDSDPDIREMAQEEYKEAKAQILTIEDEIQVLMLPKDPKDNNNVYLEVRAGTGGDEAAIFAGDLFRMYSRYAETKKWKVDVVTTNEGEHGGYKEIIANISGEGVFGQLKFESGVHRVQRVPETESQGRVHTSACTVAVMAEVPEAEAIEINSADLKVDTFRASGAGGQHVNKTDSAIRITHIPTGVVVECQDQRSQHKNRAKAMSVLAARLQQAEDEKRDAAEASERRNLVGSGDRSERIRTYNYPQGRITDHRINLTLYRLNEVVAGDLSCIVEPLMQEHQADLLAAMGDE
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNBI_SUHVF
Sequence: MEAAAKTVTVRAAPLGYVYVTPIEALRRDLLALLVARSADDAAAVAPLVRGLTVEAGFAGHVAVVAGARTTGLGGGLTLKLTPNHFHPNVFFFHNGDCVPPSSAAPALSRACEAARARFGFSAYRTPVDNAEETTGAEVCARLGLAADAHAAYLVVADGFKEAVYLCNAFLHYGGAGTVSINGHEAWRVPLYPVHLFMPDVNRLVADPFNAKNRSISEEFVYPRPFFNGPLCRLLHGYVLGPAAVATRVRNLDAVARGAAHLAFDENHESAVLPADVTFTLFEQRRRGGDAAAGGLERRMASVMSADAALSLEALVAAGVYDEEPPALDDWPVLSEAGAKDGGAAAASAGAPVSQAAALGAYVSRAAGLVGALVFSSNSVLYLTEVDDAGAADARKEGAGPSFNRFYQVAAPYLAGNPQTDKDGRVLLHTASQPATAPGNHDFAMDHLVMACGFCPQLLARVLFYLERCDAGTFVGRGDVDAVRYVAGSLDAEVPCSLCDRASRPACAHTTLHRLRHRSRASARRRSPMGVFGTMNSAYSDCDVLGNYASYGALKRPNDSEPPKAIMQDTYRAAVDRLLADVAGARIGETVTDHAGFRHALRALRDTVEQAADRFVRTLVETRDFKLRDALYDANHTMSLSLDPYSGALCPATSFLARRTLLAVLQDLALSQCHGVLHGQPVEGRNFRNQFQPVLRRRVVDMLNGGFVTAKTVTVTLADGIVAPDPTKGSAEPPARDHDGDLARVSFEVLRELRVKSRVMFSTGSGSLSDAARARVAGLAGAYQRPDTAVDVLNGPLGFLLKQHHATLFPRGKPPGGQSPNPQWFWTLLQRNQLPARLLTKDDIETIAAVKRFSVDYGAINYVNLTPGTVAELAQFYLANLILRYCDHKQFFINSLTGITMQSKRPRDPAAVMAWVRRPLADAADAERAAREVLDAPRDDTWVATYTSSHLLRSVMASRPLVVLGLGVSKYHGMAGNNRVFQAGNWSGLNGGKHVCPLMVFDRTRHFVLACPRVGFTCSQTGGGAGLHDHSLGEHVKTILADGGPLVQTAVYAAVLHALGARTQHLEPDDWRAIVDDEFLAAALAEINGRVADRDGRWSVEAAAELVRDLEGQTGADGGEETAFDFGACGAGGDVAGLAPASLVPAELGGKRPPPEDDLFDMGAPPEKRLTFDML
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: TTC9C_RAT
Sequence: MEKRLQEAQLYKEEGNQRYREGKYRDAVSRYHRALLQLRGLDPSLPSPIPNLGPQGPALTPEQENILHTIQTDCYNNLAACLLQMEPVKYERVREYSQKVLERQPENAKALYRAGVAFFHLQDYDQARHYLLAAVNRQPKDANVRRYLQLTQSELSSYHRKEKQLYLGMFA
What are the official names of this protein?
Tetratricopeptide repeat protein 9C, TPR repeat protein 9C.
What is the protein family that this protein belongs to?
Belongs to the TTC9 family.
Protein: Y2748_LISMF
Sequence: MEITVVKGDITEQDVDVIVNAANPGLLGGGGVDGAIHQAAGPDLLKECQEVINRIGTCPAGEAVITSAGDLQASYIIHAVGPIWKDGEHQEANKLASCYWKALDLAAGKELTSIAFPNISTGVYGFPKKLAAEVALYTVRKWAEEEYDTSIEEIRFVCFDEENLKLYNKLINSEVV
What are the official names of this protein?
Macro domain-containing protein LMOf2365_2748.
Protein: FADA5_MYCTU
Sequence: MGYPVIVEATRSPIGKRNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQFGEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAMSRVGLGANAGPDRSLIRAQSWDIDLPNQFEAAERIAKRRGITREDVDVFGLESQRRAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLRETTMAGLGELKPVLEGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDGPVQSTAKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSRLITTALHELERTDQSLALITMCAGGALSTGTIIERI
What is the function of this protein?
Involved in the beta-oxidation of the cholesterol side chain (PubMed:19822655).  It is important for utilization of cholesterol as a sole carbon source in vitro and for full virulence in the chronic stage of mouse lung infection (PubMed:19822655).  Catalyzes the thiolysis of 3,22-dioxochol-4-en-24-oyl-CoA to yield 3-oxo-4-pregnene-20-carboxyl-CoA (3-OPC-CoA) and acetyl-CoA (PubMed:25482540).  Also able to use acetoacetyl-CoA (AcAcCoA) as substrate (PubMed:19822655).
What are the official names of this protein?
Steroid 3-ketoacyl-CoA thiolase, Acetyl-CoA acetyltransferase FadA5, Beta-ketoacyl-CoA thiolase.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
Protein: KDSB_CUPNH
Sequence: MTVPAFTVVIPARLASTRLPDKPLADIGGRPMIVRVAERAHASSAQRTVVATDAPAVAQACAAHGIEAVLTRADHPSGTDRLSEVAAQLGLADDAIVVNVQGDEPLIEPSLIDEVALHLAHHADCAIATAAHPLQDIAEVFNPNVVKVVCDAAGRALYFSRAPIPWARDAWSGVPAVPAALAQVPLPGMPVLRHIGLYAYRAGFLRRFPTLAAAPLEQTEALEQLRAMWHGERIAVLQTSAAPAPGVDTPADLERVRALWAQSMAQEGP
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARR2_YEAST
Sequence: MVSFITSRQLKGLIENQRKDFQVVDLRREDFARDHITNAWHVPVTAQITEKQLNQLIKGLSDTFSSSQFVKVIFHCTGSKNRGPKVAAKFETYLQEEDITSKFESCILVGGFYAWETHCRESNLKLIVSG
What is the function of this protein?
Involved in resistance to arsenic compounds.
What are the official names of this protein?
Arsenical-resistance protein 2.
Protein: ACD_DESML
Sequence: MDFNLSKELQMLQKEVRNFVNKKIVPFADQWDNENHFPYEEAVRPMGELGFFGTVIPEEYGGEGMDQGWLAAMIVTEEIARGSSALRVQLNMEVLGCAYTILTYGSEALKKKYVPKLSSAEFLGGFGITEPDAGSDVMAMSSTAEDKGDHWLLNGSKTWISNAAQADVLIYYAYTDKAAGSRGLSAFVIEPRNFPGIKTSNLEKLGSHASPTGELFLDNVKVPKENILGKPGDGARIVFGSLNHTRLSAAAGGVGLAQACLDAAIKYCNERRQFGKPIGDFQMNQDMIAQMAVEVEAARLLAYKAAAAKDEGRLNNGLDVAMAKYAAGEAVSKCANYAMRILGAYGYSTEYPVARFYRDAPTYYMVEGSANICKMIIALDQLGVRKANR
What is the function of this protein?
Catalyzes the dehydrogenation of Glutaryl-CoA to glutaconyl-CoA.
What are the official names of this protein?
Glutaryl-CoA dehydrogenase, GDH(Des).
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: PQQE_ERWT9
Sequence: MNPSESNVKPPLWLLAELTYRCPLQCPYCSNPLDFAQQEKELSTAQWIEVFKQARAMGAVQIGFSGGEPLVRKDLPELIRSARELGFYTNLITSGIGLTQKKIDAFAEAGLDHIQISFQASDETLNAALAGSQKAFQQKLEMARAVKAHGYPMVLNFVLHRHNIDQLDRIIELCIELEADDVELATCQFYGWAQLNREGLLPTRDQLVRAEAVVHRYREKMAASGNLANLLFVTPDYYEERPKGCMGGWGAIFLSVTPEGMALPCHSARQLPIRFPSVLEHSLQDIWFNSFGFNRYRGFDWMPEPCRSCDEKEKDFGGCRCQAFMLTGNADNADPVCSKSEHHGTILAAREQANCTNIQVNQLRFRNRANSERVNSQLIFKG
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: Y189_ARCFU
Sequence: MPTHQCHIIRAVPVVRYVVALLHWLLWRVVVIIAISVPVFHHPFRNLRPCHFRPSWVCNRILRTSSFPMVLPSQHRALPSHQHQHYANLLPIHFTS
What are the official names of this protein?
Uncharacterized protein AF_0189.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.