PharMolix/UniProtQA huggingface dataset:
Protein: IL1B_CAPHI
Sequence: MATVPEPINEVMAYYSDENELLFEADGPKQMKSCTQHLDLGSMGDGNIQLQISHQLYNKSFRQVVSVIVAMEKLRSRAYEHVFRDDDLRSILSFIFEEEPVIFETSSDELLCDAAVQSVKCKLQDREQKSLVLDSPCVLKALHLLSQEMSREVVFCMSFVQGEERDNKIPVALGIRDKNLYLSWVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKNTVEFESVLYPNWYISTSQIEEKPVFLGHFRGGQDITDFRMETLSP
What is the function of this protein?
Potent pro-inflammatory cytokine.  Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.  Promotes Th17 differentiation of T-cells.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells.  Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-1 beta, IL-1 beta.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Secreted. Lysosome. Secreted, extracellular exosome. Note=The precursor is cytosolic. In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: FAR4_TYRGL
Sequence: GVDSSFVRL
What is the function of this protein?
FMRFamides and FMRFamide-like peptides are neuropeptides.
What are the official names of this protein?
Extended FMRFamide-4, FMRFa-4.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRF amide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYD_SALNS
Sequence: MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDAKNVNADMATGEIEVLASSLTIINRADSLPLDANHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELVDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGAQLSRKQIDDYGNFVKIYGAKGLAYIKVNERAKGLDGINSPVAKFLTADIVEAILERTGAQDGDMIFFGADNKKVVADALGALRLKLGKDLSLTDEDKWAPLWVIDFPMFEDDGEGGLTAMHHPFTAPRDMTASELKTAPEEAVANAYDMVINGYEVGGGSVRIHNGEMQQTVFGILGINEQEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTEAPSFANQAALTELGIQVVKKAENN
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTU1_HAEI8
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKHYGGAARAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALQALNGVAEWEEKILELAGHLDTYIPEPERAIDQPFLLPIEDVFSISGRGTVVTGRVERGIIRTGDEVEIVGIKDTAKTTVTGVEMFRKLLDEGRAGENIGALLRGTKREEIERGQVLAKPGSITPHTDFESEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMTVSLIHPIAMDQGLRFAIREGGRTVGAGVVAKIIK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu 1, EF-Tu 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_LISMC
Sequence: MSKVLEQVEAIVTPITDELQLELVDIAFEKEGPNWFLRIFIDKDGGVDIDECAAVSEKVSEKMDENDPITQNYFLEVSSPGAERPLKKEQDFENAVSKYVHVTSYEPIDGRKMWEGTLVSYDGTTLVITITDKTRKITCEIPKDKVAKARLAIQF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP5_ARATH
Sequence: MAEVSMGSSSSSTDLSPEEERVFIRDIAIAAEANSKEGDTFYLITQRWWQEWIEYVNQDQPCNTNDGSSLSEHCDSPGSSTLKKPSRIDNSDLIYDSSLEDPSNTSEIIETLQEGRDYVLLPQEVWNQLRSWYGGGPTLARRVISSGLSQTELAVEVYPLRLQLLLMPKSDHSAIRISKKETIRELHRRACEIFDLDSEHVRIWDYYGHQKYSLMNDLDKTLDDANLQMDQDILVEVLDINGTLSSAHIQSAQENGLVDGDSTSILIEPSKSSLAAAGGFSSSRNAFRTGSVEVSQSFDNTYSSTGVTTRGSTAGLTGLLNLGNTCFMNSAIQCLVHTPEFASYFQEDYHQEINWQNPLGMVGELALAFGDLLRKLWAPGRTPIAPRPFKAKLARFAPQFSGYNQHDSQELLAFLLDGLHEDLNRVKHKPYINSRDADGRPDEEVADEFWKNHIARNDSIIVDVCQGQYKSTLVCPICNKVSVTFDPFMYLSLPLQFNTTRAITVTVFSCDKTALPSTITVNVSKQGRCRDLIQALTNACSLKQSEELKLAEIRNNFIHRLFEDPLIPLSSIKDDDHLAAYKLSKSSENTTLLRLVLRRRDQKAGERESTVQLKPCGTPLLSSASCGDALTKGKIHCLVQNMLSPFRREESVGKKGNSDSSIPERRSARFNNTEEEDKVGGLKKAKKSNSSDLGASKLSLQLIDEDNKTINLPDNEAEAMKLPSSATVTIYLDWTPELSGMYDITCLESLPEVLKYGPTTKKARSEPLSLYACLEAFLREEPLVPDEMWFCPQCNERRQASKKLDLWRLPEVLVIHLKRFSYSRSMKHKLETFVNFPIHDLDLTKYVANKNLSQPQLYELYALTNHYGGMGSGHYTAHIKLLDDSRWYNFDDSHISHINEDDVKSGAAYVLFYRRKSDAGGKMT
What is the function of this protein?
Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin.  Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 5, Deubiquitinating enzyme 5, AtUBP5, Ubiquitin thioesterase 5, Ubiquitin-specific-processing protease 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: IL10_CAVPO
Sequence: MPGSALLCCLALLAGVKASQGTNTQSEDSCAHFPAGLPHMLRELRAAFGRVKTFFQTQDQLDNVLLNKSLLEDFKGYLGCQALSEMIQFYLVEVMPQAEKHGPEIKEHLNSLGEKLKTLRMRLRRCHRFLPCENKSKAVEQVKSDFNKLQDQGVYKAMNEFDIFINCIEAYMMIKMKS
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYDND_RICFE
Sequence: MHKYRTHNCNELQISDVRKEVKLSGWVHRRRDHGNLVFIDLRDHYGITQIVFTDQNQQLMEDASRLRYESVITVRGTIVARSNDTINDTLPTGHIEVLAGEFIVESAADTLPFVINTEKDAPEETRLKHRFLDLRREKLHNNIILRSQIISHIRHLMTGRGFTEFQTPILTASSPEGARDFLVPSRMHPGKFYALPQAPQQFKQLLMVSGFDRYFQIAPCFRDEDARADRSPGEFYQLDVEMSFVTQEDIFSTIEPVMYDLFTKFTAKKVSETPFVRIPYNESMLKYGSDKPDLRNPIIIADVTEIFRDSDFTIFRENIKKGSIVRAIPAPKAAALPRSFFDKMIEFAISEGAGGLGYIQFSETGEAKGPVAKFLSPQQLESLKATASISNGDAVFFASDKKEKAAKLAGKVRIRLGEELDLLEKDCFKFCWITDFPFYELNEDTGKIDFSHNPFSMPQGGLEALEQAKTTEELLELTAYQYDIVCNGIELSSGAIRNHKPEIMYKAFSMAGYSEEEVDKRFGGMIRAFKFGAPPHGGIAPGIDRIVMLLAEATNIREIIAFPLNQQAEDLLMNAPSYVEDKALKELSIMLSPSILKNMK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPNP_PSEAE
Sequence: MFKVNEYFDGTVKSIAFDMTAGPATIGVMAAGEYEFGTSQLEIMHVVAGALTVKLPGSDEWQEYASGSQFTVPANSKFQLKVAQDTAYLCEYR
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: TRUB_ANAPZ
Sequence: MKHGWLNIDKPYGVSSGSVVGKLKKMLQCKVGHAGTLDPLATGVLPIAFGEATKTTNYATDTLKSYEVTIQWGEQRDTDDKEGKIIRTSTLRPTEHSIKEALQQYVGVIQQIPSTFSAIKVGGMRAYSLSRMGKEVALAPRSVCITEIELLSVDSGSNTADLRITCGKGVYVRAVARDLGITLGCYGYVARLRRTMVGPFTEANIVTLQELETLVGENKLEEAVFPLSIVMSGLPHIEIDVETAKVVKNGRNIRLVDAALNGLYIVENCDMCYLSQAGGVPVAICEVVDGTAKPVRVFNV
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: MTRE_METBU
Sequence: MEPLMGMGVLALMGAAATIAGTTEDLESDVGSQSNPNSQVQLAPQMMYPHRIYNKAISGEPPSNALICAIGGTVASVLMTANLSVIFAIAIGALVASAVHGTYCITAYMGRTASQKRFRQPIYLDILRSHTPVMMGYAFITTFCILVVSYIMVAVLAHPFPLTLLAFIWGITVGAIGSSTGDVHYGAEREFQNVEFGSGLNAANSGNIVRKAESGLRNGIDNSWFCAKFGGPVTGLAFGMTVFLSGWVTAVFNPAISLTMGWLSVAAGVILVLLLIIWNRKIEVAARKAFGPYKEEEEVAA
What is the function of this protein?
Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin.  This is an energy-conserving, sodium-ion translocating step.
What are the official names of this protein?
Tetrahydromethanopterin S-methyltransferase subunit E, N5-methyltetrahydromethanopterin--coenzyme M methyltransferase subunit E.
What is the protein family that this protein belongs to?
Belongs to the MtrE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYB_AKOBU
Sequence: MKILRKNHPLLKIVNHSFIDLPTPSNISSWWNFGSLLGVCLIIQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWLIRYLHANGASMFFICLFIHVGRGIYYGSYVLSETWNIGIILFLTTMATAFVGYVLPWGQMSFWGATVITNLLSAVPYIGSTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAFALVHLLFLHETGSNNPSGLNSDSDKIPFHPYYTIKDLLGIFLLLMALMILALFFPDVLGDPDNFTPANPLNTPAHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAAFPLLNTSKQHGLIFRPVTQAIYWTFIANLLVLTWIGGQPVEYPFTTIGQIASITYFTIIIILMPVSNTIENNIIKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PARP8_MOUSE
Sequence: MGMCSRQERIQKDIDVVIQKSRAEKDCLFADFRYSDSTFTFTYVGGPKSVSYSVHVSEDYPDNTYVSSSENDEDVLVTTDPIPVIFHRIATELRKTNDINCCLSIRSKLQKENGEESRQNSTVEEDSEGDNDSEEFYYGGQVNYDGELHKHPQLEADLSAVRELYGPHAVSLREYGAIDDVDIDLHIDVSFLDEEIAVAWEVIRTEPIIVRLHCSLTQYLNGPVPTVDVFQISTKERFGLGHQLKKIMQTFVSQQWKQSKDKSNCPHGKKLSEKKVKSPLHLFSTLRRSPSYPPPGCGKSKSKLKPEQDGISKTHKLLRRTCSSTVKADDMCAKSHRTFGRSLSSDPRAEQAMSTIKSHKLLGRPCPSAGKQEDCLTLKSHKLLTRSCSGDPRCEHNTNLKPHKLLSRSYSSNLRMEELYGLKNHKLLSKSYSSAPKTSKMEHFKEPNAEGRRLSLTSGLIGILTPSSSSSQPPTNGAKSIPIRDRGFLVQTIEFAEQRIPVLNEYCVVCDEPHVFQNGPMLRPTVCERELCVFAFQTLGVMNEAADEIATGAQVVDLLVSMCRSALESPRKVVIFEPYPSVVDPNDPQMLAFNPRKKNYDRVMKALDSITSIREMTQAPYLEIKKQMDKQDPLAHPLLQWVISSNRSHIVKLPVNRQLKFMHTPHQFLLLSSPPAKESNFRAAKKLFGSTFAFHGSHIENWHSILRNGLVVASNTRLQLHGAMYGSGIYLSPMSSISFGYSGMNKKQKVSSKDEPASSSKSSNASQSQKKGQQSQFLQSRNLKCIALCEVITSPDLHKHGEIWVVPNTDHVCTRFFFVYEDGQVGDANINTQEGGIHKEILRVIGNQTATG
What is the function of this protein?
Mono-ADP-ribosyltransferase that mediates mono-ADP-ribosylation of target proteins.
What are the official names of this protein?
Protein mono-ADP-ribosyltransferase PARP8, ADP-ribosyltransferase diphtheria toxin-like 16, ARTD16, Poly [ADP-ribose] polymerase 8, PARP-8.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
Protein: PPK1_MYCA1
Sequence: MMRHDRNVTEIDAETRPDENLWHSGDSAVGAPPAATPAAMTDLPEDRYLNRELSWLDFNARVLALADDNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPRKQLALIGEHTQRIATRHARVFLDSVRPALAEEGIHIVTWADLDQAERDELSTYFTEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVMVRQTEDGGQHFARVKVPNNVDRFVELAAPRAGAEGENRGVVRFLPMEELIAAFLPLLFPGMEIVEHHAFRITRNADMEVEEDRDEDLLQALERELARRRFGPPVRLEIADDMTEGMLELLLRELDVHPGDVIEVPGLLDLSSLRQIYDLDRPALKDPAFVPDTHPAFADRESPKSIFATLREGDVLVHHPYDSFSTSVQRFIQQAAADPNVLAIKQTLYRTSGDSPIVRALIEAAEAGKQAVALVEIKARFDEQANIRWARALEQAGVHVVYGLVGLKTHCKTCLVVRREGSAIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKVSYRNLLVAPHGIRTGIIERVEREIAAHRERGQGRIRLKMNALVDEQVIDSLYRASQAGVRVEVVVRGICALRPGVQGYSENIFVRSILGRFLEHSRIIHFRNINEFWIGSADMMHRNLDRRVEVLAQVKDPKLTAQLDELFESALDPSTRCWELGPDGQWTPSPQEGHTVRDHQVSLMERHRSP
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: CYB_PIPKU
Sequence: MTNIRKTHPLIKIVNDSFIDLPTPSNISAWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWVLRYLHANGASMFFICLYLHVGRGLYYGSYLFKETWNMGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTDLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVMVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGLFTMILVLLSLVLFSPDMLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVIIPFLHTSKQRSMTFRPLSQCLFWLLTADLLTLTWIGGQPVEHPYVIIGQLASILYFLIIIVIMPLVGLVENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS15_METS5
Sequence: MNKRRANGSSHSTRPVRTGSPKWVRFSREEVEMLIEELAKKGYTPSMIGIVLRDQYGIPLAKPIIGKKVNQFLKDKGLASQIPEDLFNLIRRAVNVRRHLNEYPGDKTAKKGLEEIESKIRRLSRYYKRVEKLPQDWTYDPAKAELLVSASS
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: Y1554_CROS8
Sequence: MSITAKSVYRDTGNFFRNQLVTILLIALLCAFISMMLGHAFTPNADQLAILSEGDAMTNSASLFELVQNMTPEQQQVLLKASAASTFSGMFGNTLLVGGVLVLIQAVSAGQNVSALRAIGASAPLLPRLFILIFLTTFLVQMGILLVVVPGVILAIVLSLAPVMMAQDKAGIFRAMRNSMRLAWRNMRLVAPAVLLWLLARAALLLFAPAFAALTPQIGAVVAGTLSNLLTALLLIYLFRLYMLIRE
What are the official names of this protein?
UPF0259 membrane protein ESA_01554.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MTNA_ANOGA
Sequence: MTLEAIKYKSGQLQILDQLLLPAESKYIPVAGVKDGWSAIHKMQVRGAPAIAIVGCLSLVVEIYDKQYETKAALANEIGEHLQYLVTSRPTAVNLKLAADDVKGQVESLLANETVTVDGMKQEVIKAIEYMLEKDISDNRAIGDNGANVLVKGVDRPLKLLTHCNTGSLATAGYGTALGVIRSVNERNLLEHVYCTETRPYNQGARLTAYELVHDKLPATLVTDSMVAALLNSRKIDAIIVGADRVAANGDTANKIGTYQMAVVAKHHGVPFYVAAPFTSIDVAIEDGSHIKIEERPEHELTHIGGQRIAAPGIGCWNPAFDVTPAELITGIITERGVLKPCELAEKVRQK
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TM6S1_PONAB
Sequence: MSASAATGVFVLSLSAIPVTYVFNHLAAQHDSWTIVGVAALILFLVALLARVLVKRKPPRDPLFYVYAVFGFTSVVNLIIGLEQDGIIDGFMTHYLREGEPYLNTAYGHMICYWDGSAHYLMYLVMVAAIAWEETYRTIGLYWVGSIIMSVVVFVPGNIVGKYGTRICPAFFLSIPYTCLPVWAGFRIYNQPSENYNYPSKVIQEAQAKDLLRRPFDLMLVVCLLLATGFCLFRGLIALDCPSELCRLYTQFQEPYLKDPAAYPKIQMLVYMFYSVPYFVTALYGLVVPGCSWMPDITLIHAGGLAQAQFSHIGASLHARTAYVYRVPEEAKILFLALNIAYGVLPQLLAYRCIYKPEFFIKTKAEEKVE
What is the function of this protein?
May function as sterol isomerase.
What are the official names of this protein?
Transmembrane 6 superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the TM6SF family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: DCE1_CANLF
Sequence: MASSTPSSSATSSNAGADPNTANLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFKERQSSKNLLSCENSDRDGRFRRTETDFSNLFARDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIVGWSSKDGDGIFSPGGAISNMYSIMAARYKFFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGIPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL
What is the function of this protein?
Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor.
What are the official names of this protein?
Glutamate decarboxylase 1, 67 kDa glutamic acid decarboxylase, GAD-67, Glutamate decarboxylase 67 kDa isoform.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: TRMB_PICGU
Sequence: MSTDSESKRRAYREEKEGARKKSVKLAPEATPESKPDLPRKRYYRQRAHSNPFSDHSLDYPRNPDAMEWGKLYPEYANTDKKVEIADIGCGYGGLMIGLAKEYPQTMILGMEIRVQVTQYVEDRIIALREKHEKDEVNYQNIAVLRGNAMKFLPNFFHRGQLKKMFFCFPDPHFKQRKHKARIITTTLLSEYAYVLREEGVLYTITDVEDLHIWMVKHLDDHPLFERLDKEWEKNDKCVSIMYGSTEEGQKVARNKGSKFVACFRRVANPEE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, Transfer RNA methyltransferase 8, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PNP_BIFAA
Sequence: MEGPEIKAVEAVIDNGSFGKRTLRFETGRLAQQADGAVAAYLDDDSMILSTTTAGSSPKENYDFFPLTVDVEEKMYAAGKIPGSFFRREGRPSSEAILACRIIDRPLRPLFPHTLRNEVQVVETVLAVNPDDAYDVVALNAASASTMISGLPFEGPVSGVRLALIDGQWVAFPRWSERERAVFEIVVAGRVVENGDVAIAMIEAGAGKNAWHLIYDEGQTKPDEEVVAGGLEAAKPFIKVICEAQAELKKIAAKETKEFQLFPEYTEDLYNRIDEIAHADLDEALSIAEKLPRQDRIHEIKEGVKATLAGEFTDMEDAEKDKEIGNAFKELQRQIVRRRILTQDYRIDGRGLRDIRTLSAEVDIVPRVHGSALFQRGETQILGVTTLNMLKMEQQIDALSGPQSKRYMHNYEMPPYSTGETGRVGSPKRREIGHGALAEKALVPVLPSREEFPYAIRQVSEAIGSNGSTSMGSVCASTLSLLAAGVPLKAPVAGIAMGLVSGDVDGQHIYKTLTDILGAEDAFGDMDFKVAGTSEFITALQLDTKLDGIPADILASALQQAKEARTTILEVINECIDGPAEMSPYAPRIITTTVPVDKIGEVIGPKGKMINQIQEDTGAEIAIEDDGTVYISSEGGEAAEKAKEIIDQIANPHVPEAGETYNGKVVKTTSFGAFVNLTPGTDGLLHISQIRNLANGERIDAVEDVLKEGDTVEVVVQGVDDRGKISLAIPGFEDQESSAPRRDRGDRDDRRGGRGRRDDRRRSDDRDDRDYDDRPRRRRSDRDDDRDYDDRPRRRRSDRDDRDYDRDDRRSSRSDRDDRDYDDRPRRRRSDRDDRDYDRDDRRSDRRRGSRRDDRNPRYAADENYDEYRADREERSERPRRRVRRDFDPFED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOQC_BACSU
Sequence: MEVNVKTNQREKFIRNGIPYDELDTQMIHLIDILNFKIGLKTRHCCFGHKPYEEIQVMFEDEVNIKEDQILELAELAGREWKGLQLSFSKWARFSPLMFNWSLVLSKRFRNPEDPNKYRYLRSVEEFFESYAAKK
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YoqC.
Protein: RECG_ACIFR
Sequence: MSTSTNFSQSGHVARPCRARNSMAGAKAGLYLQSSVSALRGVGPALVPRLQHMDLWRVQDVLFHLPSRYQDRRHIASMATLQAGQECAILGEIVRVDHQRGGREQWLVTVSDGSGRLQIRLFHMTVALRAQWQVGRRLWCFGELRGGFHGLEMIHPEWQMADVPQFQAPRHLTPFYPSSEGITQAQWRRWMAQALTLLDQLPDYLENRLPPQWPGLREGLRLLHESADEIPSPQHPAWQRLALEELLANHLAVRRMRQSGMMQNAPCLRSKGQLWHRFLAHLPFSPTMAQERVIAEINADLVRHRPMRRLLQGDVGSGKTLVAAAATLTALEAGYQVAMMAPTEILAEQLHARFQQWLEPLGLEVGYLVGSRSPRARRETAETLAGGSLRLVIGTQSLFQEGVVFACLGLVIIDEQHRFGVEQRRQLLEKGAMPHLLVMTATPIMVEDGITVSGILLFGRTPNRFLPQAGIDAVAFPGVDKDYAARERAALRGPMTPLLNDAGDIVEAGLVEQAIAFVQRNTAIGGQLEEGGARRENLPAYPREAIREAIVNALIHRDYLLSSTDIELSIYEDRLEITSPGRLPNGITPARMLTGCRATRNQLIKDVMRDYRYLEHSGMGVPRKIVKCMREHNGTEPQLIEDGELFTVRLLR
What is the function of this protein?
Critical role in recombination and DNA repair.  Helps process Holliday junction intermediates to mature products by catalyzing branch migration.  Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity.  Unwinds branched duplex DNA (Y-DNA) (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase RecG.
What is the protein family that this protein belongs to?
Belongs to the helicase family. RecG subfamily.