PharMolix/UniProtQA huggingface dataset:
Protein: PCGF1_BOVIN
Sequence: MASPQGGQIAIAMRLRNQLQSVYKMDPLRNEEEVRVKIKDLNEHIVCCLCAGYFVDATTITECLHTFCKSCIVKYLQTSKYCPMCNIKIHETQPLLNHKLDRVMQDIVYKLVPGLQDSEEKRIREFYQSRGLDRVTQPSGEEPALSNLGLPFSSFDHSKAHYYRYDEQLSLCLERLSSGKDKNKSILQNKYVRCSVRAEVRHLRRVLCHRLMLNPQHVQLLFDNEVLPDHMTMKQIWLSHWFGKPSPLLLQYSVKEKRR
What is the function of this protein?
Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A.  Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway.  Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element).  Promotes cell cycle progression and enhances cell proliferation as well.  May have a positive role in tumor cell growth by down-regulating CDKN1A.  Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.  Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.  Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells.
What are the official names of this protein?
Polycomb group RING finger protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2364_STAA9
Sequence: MLYPIFIFILAGLCEIGGGYLIWLWLREGQSSLVGLIGGAILMLYGVIATFQSFPSFGRVYAAYGGVFIIMSLIFAMVVDKQMPDKYDVIGAIICIVGVLVMLLPSRA
What are the official names of this protein?
UPF0060 membrane protein SaurJH9_2364.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CINA_STRP6
Sequence: MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVITTASQRSDLVILCGGLGPTKDDLTKQTLAKYLRKDLVYDEQACQKLDDFFAKRKPSSRTPNNERQAQVIEGSIPLPNKTGLAVGGFITVDGISYVVLPGPPSELKSMVNEELVPLLSKQYSTLYSKVLRFFGVGESQLVTVLSDFIENQTDPTIAPYAKTGEVTLRLSTKTENQALADKKLGQLEAQLLSRKTLEGQPLADVFYGYGEDNSLARETFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVAYSMEEKAKMLGLPLEELKSHGVVSAYTAEGMAEQARLLTGADIGVSLTGVAGPDMLEEQPAGTVFIGLATQTKVESIKVLISGQSRLDVRYIATLHAFNMVRKTLLKLENLL
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: TBP_PICTO
Sequence: MSEMEKITIENIVASTSLAEHLDLSKIALALEGSEYEPEQFPGLIYRLQEPKTAVLIFRSGKVNCTGAKNLDDVKKTIDIIIDKLKKADIEVYDNPDIIVQNIVAVYDLESNLNLTDIAMSLGLENVEYEPEQFPGLVYRVEEPKVVLLLFGSGKVVCTGAKEENEIEQAVIKVKKDLQKVGLI
What is the function of this protein?
General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase.  Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
What are the official names of this protein?
TATA-box-binding protein, Box A-binding protein, BAP, TATA sequence-binding protein, TBP, TATA-box factor.
What is the protein family that this protein belongs to?
Belongs to the TBP family.
Protein: NUOI_ORITI
Sequence: MKITNFTKSFLLYEIIVGMFLTLKYFFKSKVTIRYPNEVSKLSPRFKGEHALRRYPDGEERCIACKLCEAICPAQAITIEAKEQPNGSRRTTKYDIDMTKCIYCGLCQEACPVDAIVEGPNLEFATETHQELLYNKEKLLRNGDMWEHVIAKNLKVDSIYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RIBL_METTH
Sequence: MKTVMATGTFDIIHPGHGFFLEEARKLGGEDARLVVVLARDSTVRARKRTPIVGEKQRLEVVRMLKPVDEAYLGSETDMFEIVHRIKPDIIAIGPDQKFDVDELRDELRRRGLGCEVRRIEKYRDAELDSTCKIIKRIRSMEFDEDSLKNC
What is the function of this protein?
Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
What are the official names of this protein?
FAD synthase, FMN adenylyltransferase, Flavin adenine dinucleotide synthase.
What is the protein family that this protein belongs to?
Belongs to the archaeal FAD synthase family.
Protein: COQ4_ASPNC
Sequence: MTVLRTRSAVQHARELNNFLSCAAPLSLRSHSRPISGFNRPPPNYPGHVPLNFVERGALAVGSAVGALLNPRRADLIAACGEATATPYFIYRLRDAMLSDPTGRQILRDRPRITSETLKLPYLRSLPENTVGRTYATWLDREGVSPDTRDNVQYIDDEECAYVMQRYRECHDFYHAVTGLPIFVEGELALKAFEFLNTLIPMTGLSLFASVRLKPAERERLFSIYLPWALRSGLRSKELINVYWEKVLEKDVGELREELGIERPPDMREIRRMIRMQKKREKELMEQRGQ
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein coq4, mitochondrial, Coenzyme Q biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: GYRA_STRP8
Sequence: MQDRNLIDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHRRILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVDGHGNFGSMDGDGAAAQRYTEARMSKIALELLRDINKNTVNFQDNYDGSEREPVVLPARFPNLLVNGATGIAVGMATNIPPHNLAESIDAVKMVMEHPDCTTRELMEVIPGPDFPTGALVMGRSGIHRAYDTGKGSIVLRSRTEIETTQTGRERIVVTEFPYGVNKTKVHEHIVRLAQEKRLEGITAVRDESSREGVRFVIEIRREASATVILNNLFKLTSLQTNFSFNMLAIENGVPKILSLRQIIDNYISYQKEVIIRRTRFDKDKAEARAHILEGLLIALDHLDEVIAIIRNSETDVIAQTELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIADLSDILAKPERIITIIKEEMDEIKRKYANPRRTELMVGEVLSLEDEDLIEEEDVLITLSNKGYIKRLAQDEFRAQKRGGRGVQGTGVNNDDFVRELVSTSTHDTLLFFTNFGRVYRLKAYEIPEYGRTAKGLPIVNLLKLEDGETIQTIINARKEETAGKSFFFTTKQGIVKRTEVSEFNNIRQNGLRALKLKEGDQLINVLLTSGQDDIIIGTHSGYSVRFNEASIRNMGRSATGVRGVKLREDDRVVGASRIRDNQEVLVITENGFGKRTSATDYPTKGRGGKGIKTANITPKNGQLAGLVTVDGTEDIMVITNKGVIIRTNVANISQTGRATLGVKIMKLDADAKIVTFTLVQPEDSSIAEINTDRENSISKNKDN
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_YERPS
Sequence: MIREERLLKVLRSPHVSEKASAAMEKNNTIVLKVAKDATKAEIKAAVQKLFEVEVEDVNTLLVKGKSKRHGQRVGRRSDWKKAYVTLKEGQNLDFIGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y1946_STRPJ
Sequence: MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESNSALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSNVNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDDVEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKLYSVLEDDEDVQKIYTNVDGF
What are the official names of this protein?
Probable transcriptional regulatory protein SPN23F19460.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNFA_ECO81
Sequence: MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIVAGWGRT
What are the official names of this protein?
UPF0060 membrane protein YnfA.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRPF_PSEFS
Sequence: MSAVRSKICGITRIEDALAAVEAGADAIGLVFYAKSPRSVNVLQARAIIAALPPFVTTVGLFVNASRCELNETLDAVPLDMLQFHGDETPDECESYQRPYIKALRVKSGDDIAAACAAYSGARGILLDTYVEGVPGGTGEAFDWSLIPPGLSKPIILAGGLTPTNVGAAIEQVQPYAVDVSGGVEQGKGIKDHSKIRAFMQAVRNSSGAM
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: XPO2_HUMAN
Sequence: MELSDANLQTLTEYLKKTLDPDPAIRRPAEKFLESVEGNQNYPLLLLTLLEKSQDNVIKVCASVTFKNYIKRNWRIVEDEPNKICEADRVAIKANIVHLMLSSPEQIQKQLSDAISIIGREDFPQKWPDLLTEMVNRFQSGDFHVINGVLRTAHSLFKRYRHEFKSNELWTEIKLVLDAFALPLTNLFKATIELCSTHANDASALRILFSSLILISKLFYSLNFQDLPEFFEDNMETWMNNFHTLLTLDNKLLQTDDEEEAGLLELLKSQICDNAALYAQKYDEEFQRYLPRFVTAIWNLLVTTGQEVKYDLLVSNAIQFLASVCERPHYKNLFEDQNTLTSICEKVIVPNMEFRAADEEAFEDNSEEYIRRDLEGSDIDTRRRAACDLVRGLCKFFEGPVTGIFSGYVNSMLQEYAKNPSVNWKHKDAAIYLVTSLASKAQTQKHGITQANELVNLTEFFVNHILPDLKSANVNEFPVLKADGIKYIMIFRNQVPKEHLLVSIPLLINHLQAESIVVHTYAAHALERLFTMRGPNNATLFTAAEIAPFVEILLTNLFKALTLPGSSENEYIMKAIMRSFSLLQEAIIPYIPTLITQLTQKLLAVSKNPSKPHFNHYMFEAICLSIRITCKANPAAVVNFEEALFLVFTEILQNDVQEFIPYVFQVMSLLLETHKNDIPSSYMALFPHLLQPVLWERTGNIPALVRLLQAFLERGSNTIASAAADKIPGLLGVFQKLIASKANDHQGFYLLNSIIEHMPPESVDQYRKQIFILLFQRLQNSKTTKFIKSFLVFINLYCIKYGALALQEIFDGIQPKMFGMVLEKIIIPEIQKVSGNVEKKICAVGITKLLTECPPMMDTEYTKLWTPLLQSLIGLFELPEDDTIPDEEHFIDIEDTPGYQTAFSQLAFAGKKEHDPVGQMVNNPKIHLAQSLHKLSTACPGRVPSMVSTSLNAEALQYLQGYLQAASVTLL
What is the function of this protein?
Export receptor for importin-alpha.  Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm.  In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form.  Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.  Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor.  CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
What are the official names of this protein?
Exportin-2, Exp2, Cellular apoptosis susceptibility protein, Chromosome segregation 1-like protein, Importin-alpha re-exporter.
What is the protein family that this protein belongs to?
Belongs to the XPO2/CSE1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Protein: BATF2_MOUSE
Sequence: MQLCGSSELLTETDLGESQKQLKKKQKNRVAAQRSRQKHTSKADALHQQHESLEKQNHALRKEIQALQTELAGWGRTLHLHERLCRVDCDPCPVLLPSGCPIQAKQPSGQPAPLGYNGCQEQLGLFQTPGSSPRAQHLSPGPCSHESPGLLPSLLPSLAFDPLMVRTPLAQLSPSPVLSASSPSGSSLLGSFSKLDPLIPSPQDQLAPPQPLRQEQPTSGRLASSDSPAALGPECSQNREHLPALPGSSTHWQKSSVAPSPQALMAFPLLSSAKVHF
What is the function of this protein?
AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system.  Selectively suppresses CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CCN1 and inhibits CCN1-induced anchorage-independent growth and invasion in several cancer types.  Possibly acts by interfering with AP-1 binding to CCN1 promoter (By similarity).  Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system.  Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes.
What are the official names of this protein?
Basic leucine zipper transcriptional factor ATF-like 2, B-ATF-2.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DNLJ_SERP5
Sequence: MESIIQQINQLRTSLRHHEYQYHVLDAPEVPDAEYDRLMGELRALESAHPELITADSPTQRVGAAPLAAFDQVRHEVPMLSLDNVFDEESFLAFYKRVQDRLKSSDPLTFCCELKLDGLAVSLLYEDGELVRAATRGDGTTGENITSNVRTIRAIPLRLTGDNIPRRLEVRGEVFMPQAGFEQMNEEARRKDGKIFANPRNAAAGSIRQLDPRITAKRPLTFFCYGVGLLEGGELPRSHWQRLMQFKDWGLPVSDRAKRCTGSDEVLAFYRQVEQDRTQLGFDIDGVVVKIDDIDLQETLGFVARAPRWATAFKFPAQEQITQVREVEFQVGRTGAITPVARLEPVLVAGVIVSNATLHNADEIERLGLRIGDTVIVRRAGDVIPQVVGVIAERRPADAREILFPQHCPVCGSDVERVEGEAVARCTGGLICAAQRKEALKHFVSRRALDVDGMGDKIIEQLVEKEYVKNPADLFRLSAGILTGLDRMGPKSAQNLVNALEKSKQTTFARFLYALGIREVGEATAANLAAHFGTLDKLLAADIEALKEVPEVGEIVAKHTRHFLDEELNQQVIQELVSDEIGINWPAPVVIVAEEIDSPFAGKTVVLTGSLSQLSRDEAKDRLTALGAKVSGSVSKKTDLVIAGEAAGSKLVKAQELGIEVIDEAEMIRLLGA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: AROE_SALEP
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANITVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTDGIGLLSDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAKIFAHTGSVHATDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGMLVGQAAHAVLLWHGVLPQVEPVIELLQQELLA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: HEM1_RUTMC
Sequence: MSQIAILSVNHQLVPVEVREKVAFTPDKLIQALNNLHHIDGIDACIILSTCNRVEIYVASNHKNSEELLSNYLAKTHNIKRDIIDSYLNYFEGNEALTHLCNVATGLDSLVLGEPQILGQLKNAYHIAKEVKTLNKLLEKLFQHTFSTAKKVRTNTQIGASPVSIAYCAVKLSEKIFEQLSEQTVLLIGAGEMIELCAHYLNQKGVNKMIVANRTIENAKKIAHLYQAQSIGLKQFSSFVYKADIIISSTAASMPIIGKGLIESALKKRKHKPIFMLDIAIPRDIEPEVGQLDDVYLYTIDDLGQVVNDNIGNREKEKGLAQEIIVKQNQVFNKWLDTIPNEQMVQSYQFGANSIKNELLEKAIKQLKNGANSEDTIRKLADQLANKLLHLPFKNIKQTSIENLSQCEGCIPYIKN
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: NREC_STAAM
Sequence: MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVMEYKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYILKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTTDPFKILSKRELEILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  Phosphorylated NreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT, and activates their expression (By similarity).
What are the official names of this protein?
Oxygen regulatory protein NreC, Nitrogen regulation protein C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IR04_HCMVA
Sequence: MQHARVYVCIASPPSRLPSAVPLPPPPAPPPLPSPPRYPFLVGWSWGTGRRPVGFCFIIFFYFLSSPFLNLGLSFPSPTYHESQMINKRVKRKKLQTFGYLSFPITRRIQSRRFPTRENRTKTRSFLFILIVNNNYRQQRNTTKNVNPQGCSCPLDAPVAILMARTAISV
What are the official names of this protein?
Uncharacterized protein IRL4, TRL4.
Protein: TERE_SERMA
Sequence: MAVSLVKGGNVSLTKEAPTMNVAMVGLGWDARVTDGQGFDLDASVFAVGEDGKVLSDAHFIFFNNKTSPDGAVEHQGDNRTGEGDGDDEQVKIDLTKVSADIKKLVFAVTIYDAEARKQNFGMVSNSFMRVYNNDNGTEIARFDLSEDASTETAMVFGELYRHGAEWKFKAVGQGFAGGLAALASQHGVNI
What is the function of this protein?
Not known; seems to contribute to the tellurium resistance (Ter) mechanism.  Also involved in phage inhibition (Phi) and colicin resistance (PacB).
What are the official names of this protein?
Tellurium resistance protein TerE.
What is the protein family that this protein belongs to?
Belongs to the CAPAB/TerDEXZ family.
Protein: GDT14_ORYSJ
Sequence: MARRVSTTRLLLLLLLVAAAAAAAAAGDQEDPRGGGDNGTARLDRRTKMFLHAARASDGGATGMEKAGLGLFDAFFASLSMILVSEIGDETFIIAALMAMRHPKSTVLSGALSALVVMTILSTGLGRIVPNLISRKHTNSAATVLYAFFGLRLLYIAWRSDSKASQKKEIEEVEEKLEAGQGKSTFRRIFSRFCTPIFLESFVLTFLAEWGDRSQIATIALATHKNAVGVAVGATLGHTICTSFAVVGGSMLASKISQGTVATIGGLLFLGFSLSSYFYPPL
What are the official names of this protein?
GDT1-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS14Z_NATPD
Sequence: MSDSEQTGEQAAKRTGQLETCQRCGRKQGLVGKYDIWLCRQCFREVARGMGFKKYS
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SYD_FLAPJ
Sequence: MYRSHNCGELNATHINKEVTLAGWVQKSRDKGFMNWVDLRDRYGITQLMFDESRSDKTVFELAKTLGREFVIQVKGTVIEREAKNKNISTGEIEILVTQMTILNSSLTPPFTIEDETDGGEDIRMKYRYLDIRRNPVKNSLLFRHKVAMEVRKYLSDLDFCEVETPYLIKSTPEGARDFVVPSRMNEGQFYALPQSPQTFKQLLMVGGMDKYFQIVKCFRDEDLRADRQPEFTQIDCEMAFVEQEDILNIFEGLTRHLLKELKGIEVEKFPRMTYNHAMKTYGNDKPDIRFGMEFGELNEYAKHKDFPVFNAAELVVAIAVPGVGEYSRKEIDALIEWVKRPQVGASGMVYVKCNEDGTYKSSVDKFYDQGDLSHWAKTTGAKAGDMIFVLSGPADKTRAQLSALRMELATRLGLRNPAEFAPLWVVDFPLLEFDEESGRYHAMHHPFTSPKPEDMHLLETDPKSVRANAYDMVLNGNEIGGGSIRIHDKNTQALMFKYLGFTEEEAKNQFGFLMDAFQFGAPPHGGLAFGLDRLVAILGGQETIRDFIAFPKNNSGRDVMIDAPSIIDDSQLKELHIQLDLK
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_ACICJ
Sequence: MSGTSLAKIRNIGITAHIDAGKTTTTERILYYTGVSHKIGEVHDGNTTTDYMEQERERGITITSAAVTCEWKDHRINIIDTPGHIDFNIEVNRSLRVLDGAVFIIEGVAGVQPQSETNWRLADRYNVPRIIFINKLDRTGADFYRAFDTLKEKLDIVALPLQLPIGIEDQFVGVVDLVEMKAIVWEGGELGAKFHDEEIPADMLEKAKEYRQNLLDTALSVDDAGMEEYFEKGDVATETLKRAIKTGTISGAFRPVLCGTAFKNKGVQPLLDAVLDYLPSPVDIEGIKVAPPEGEEEDPSANRRVIPANPDAPFAGLAFKIINDKYGTLTFVRVYAGTLRSGDTVLNTTKGHKERVGRMFQMHADKREEVKEVHAGDIAAFVGLKDTGTGDTLASSDDPVVLERMAFPVPVIDISVEPKTKEAVEKMTLALQKLAGEDPSLRLKTDQETGQTILSGMGELHLDIIIDRLRREYGVEANVGAPQVAYRETITREHTETYTHKKQSGGSGQFAEVKIIFEPQERNEGILFENKVVGGAVPKEYIPAVEKGIKVQADTGVLAGFPTVDFKYTLVDGKYHDVDSSALAFEIAAKACFREGMKKAGPVILEPIMDVEITTPQDHVGDVVGDLNRRRGMIQNQESSGSTVIVRAQVPLKEMFGYISNLRSMTKGRASFTMQFHHYDPVPRNIADEIMTKSA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DYL1_SCHPO
Sequence: MAVIKAVDMSEKMQQEAIHAAVQAMEKFTIEKDIAAFIKREFDKKFSPTWHCIVGRNFGSFVTHESRHFIYFYLGTVAFLLFKSG
What is the function of this protein?
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.  Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.  May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity).  Also a component of the nuclear pore complex (By similarity).
What are the official names of this protein?
Dynein light chain 1, cytoplasmic.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus, nuclear pore complex.
Protein: ATAT_XENTR
Sequence: MEFDFDVHKIFLEPITKLDSSLIPSRRPLIASSEAQKQIMTVIDEIGKASAKAQRLPAPITSASRMQTNKHHLYILKDCTPKTAGRGAVIGFLKVGCKKLFVLDQKGSHIEAEPLCILDFYIHETLQRHGFGKELFTFMLKNEQVDVHHLAIDRPSEKFLSFLRKHFNLWSTIPQVNNFVVFDGFFRDWKASVKKTPAKRTEGEIKPYSLTDRDFLKQEEGLPWPFSQSQLNLNRASSLGSSPTRACSRHSPGEEDFVKSLRNCRPHSLHRTANSEQEDHSQRRRTSSLNRPQSIHH
What is the function of this protein?
Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules.  Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity.  Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer.  Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules.  Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released.  May be involved in neuron development.
What are the official names of this protein?
Alpha-tubulin N-acetyltransferase 1, Alpha-TAT, Alpha-TAT1, TAT, Acetyltransferase mec-17 homolog.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase ATAT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane, clathrin-coated pit. Cell junction, focal adhesion. Cell projection, axon. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.