PharMolix/UniProtQA huggingface dataset:
Protein: HDOX2_STAA3
Sequence: MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
What is the function of this protein?
Allows bacterial pathogens to use the host heme as an iron source.  Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron.
What are the official names of this protein?
Heme oxygenase (staphylobilin-producing) 2, Heme-degrading monooxygenase 2, Iron-regulated surface determinant 2, Iron-responsive surface determinant 2.
What is the protein family that this protein belongs to?
Belongs to the antibiotic biosynthesis monooxygenase family. Heme-degrading monooxygenase IsdG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTE7_ARATH
Sequence: MAPAVFATLNEPSYQEQCGAVFMRKFTNQSVTENTNNLPLFNPNPNPNFERSNSSKQCDDSSEFGSYATFNLAGYTSSQLRELKKRFTSELKQIRILRERIESGTFETQQGYTIPEVPAVRSAPLNNFTGEKNDLGPKKKKQKKNVSGLKRSNQFGPSDPESEKLLAGMLNTCSQILVKLMKHKWAWVFNTPVDVVGLGLHDYHQVVKKPMDLGTVKLNLDKGFYVSPIDFATDVRLTFDNAMTYNPKGQDVYFMADKLLDHFDGMFNPAFKKFEAQQLKLTGSSSRPEPDFKPDFKQRQWNQNPPMVANPRKGTEQISIAKKLDSVKPPQPTLPPQLVEPSRVQSPSPPPPPPVIQPELPQPQPPPPQLEIEVEAPPDVSEVSKGRKGKLPKPKAKDPNKRLMTMEEKSKLGMNLQDLPPEKLGQLLQILRKRNGHLAQDGDEIELDIEAVDNETLWELDRFVTNYKKMASKIKRQGFIRNVSTPPRNMASVAEMGSAEKRTRRGDAGEEDVDIGEDIPIEDYPSVEIERDGTAVAAAASSGSSSSGSSSSSGGSSSSSDSGSGGSSSGSDSDADSVQSPFVEAKEAQC
What are the official names of this protein?
Transcription factor GTE7, Bromodomain-containing protein GTE7, Protein GLOBAL TRANSCRIPTION FACTOR GROUP E7.
What are the subcellular locations of this protein?
Nucleus.
Protein: MRAZ_ECO81
Sequence: MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LDH_CLOP1
Sequence: MIREKTNKISIIGAGFVGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSVDIKSGDYADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLVVSNPVDILTYITYKLSGFPKERVIGSGTVLDTSRLKYMLSEHFDIDARNVHTYIIGEHGDSEITAWSLTNIAGANVEEYCKTVCANCDGSFKKELPEKVKNAAYEIINSKGYTNYAVALAVTRIVEAILRDENAILTVSSLFEGQYGIDNVYLAMPTIVDRSGARQILDVPISNEEKENLIKSAEILKGHIANSELD
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRIK2_HUMAN
Sequence: MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLKIRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTESQKGKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLVEDGKYGAQDDANGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQNIGGIFIVLAAGLVLSVFVAVGEFLYKSKKNAQLEKRSFCSAMVEELRMSLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRRLPGKETMA
What is the function of this protein?
Independent of its ionotropic glutamate receptor activity, acts as a thermoreceptor conferring sensitivity to cold temperatures (PubMed:31474366).  Functions in dorsal root ganglion neurons (By similarity).
What are the official names of this protein?
Glutamate receptor ionotropic, kainate 2, GluK2, Excitatory amino acid receptor 4, EAA4, Glutamate receptor 6, GluR-6, GluR6.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein.
Protein: MTGA_YERPS
Sequence: MISVRRGLSQLWYWGKRGVIGIIALWMAGILIFAFLPVPFSMVMIERQLGAWLTGDFAYVAHSDWVPMDEISPYMALAVMAAEDQKFPDHWGFDVGAIESALSHNQRNQKRIRGASTLSQQTAKNVFLWDGRSWVRKGLEVGLTAGIELIWTKRRILTVYLNIAEFGNGIFGVEAAARHFFNKPASKLSASEAALLAAVLPNPLRFKVNAPSGYVISRQQWILRQMHQLGGKTFLQENTLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RIFK_SULTO
Sequence: MRTKILHIKGKVTAGLGEGRIFLSIPYYIESFKKYLGFEPYAGTLNIVIYDRISLENRLILDLAKGIIIPEHKEPNRVLGSVKAFPSSINSISPAAIVIPARTTHPKSVIEIISPYYLREKLSLKDGDEVEIEVYL
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: SECA_GLOVI
Sequence: MAWWNKLFGDPQERKVKKYQPRVAEMNALEAEVAALSDDQLRAKTAVFQKRVADQLQGVDLDALEIRERRRRIDVALDGVISEAFAVVREAAKRVIGLRHYDVQLIGGLVLHEGQIAEMKTGEGKTLVATLPAYLNALTGRGVHIVTVNDYLARRDSEWMGQVHRFLGLSVGLIQQSMTPSERAQNYAADITYGTNSELGFDYLRDNMATNAGELVQRSFNYCIIDEVDSILVDEARTPLIISGMVAKPAEKYMRANEVATALERNTHYEVDEKQRNVTLTDEGFIAAEQMLSTEDLFSPRDPWAHFVFNAVKAKELFNKDVQYIVRNDEVVIVDEFTGRVMPGRRWSEGLHQAVEAKEMVTIQNETQTMASITYQNFFLLYPKLAGMTGTALTEEAEFGKIYSLEVTAIPTNRKVVRTDMSDQVYKTENGKWQSVAAEIAEMNKNGRPVLVGTTSVEKSEVLSALLKEKGIAHNLLNAKPENVERESEIVAQAGRKGGVTIATNMAGRGTDILLGGNPEYMARLKLKEVLFPALVIDDEDAFSPMMRLLNNGNSRGTGFAATSKKKALPKAEIFPCELSESTKQQLKAAVDYAVAMLGADSQPALQVEELIAVASEKGPTDDPVIQHLREIYRAIYKEYQVVTDREHDEVVKLGGLHVIGTERHEARRVDNQLRGRSGRQGDPGSTRFFLSLGDNLLRIFGGERVAGLMEAFKVEEDMPIESGLLTKSLENAQRKVETFYYDQRKQVFEYDEVMNNQRKAIYAERRRALEGQDLSAVVREYIDQTVDEIVRAHVNAERPPEEWELPALIQDLQQLIPLLENQLDAVKLGEFSAVELEEDLKSQALLAYETREEYINAIQPDLMREAERYFILNQIDTLWREHLQQMDSLREMIGLRGYGQKDPLIEYKNEGYELFLQMLVEVRRNVVFALYHFQPQYNPPIDPDYVDSEYV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RL22_SYNS3
Sequence: MTTSSPTATTAQAHGRFIRGSVSKVRRVLDQIRGRTYRDALIMLEFMPYRSTGPITKVLRSAVANAEHNLGLDPASLIISQATADMGPSMKRYRPRAQGRAYAIKKQTCHISIAVAAQTDS
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: MIAA_CHLPB
Sequence: MSSAEQHTCSRPVVLITGPTASGKSALAHALAKAINAEIVSADSRQIYRGMDIGTAKPSMEMLAEVPYHFINEKEIAEEYNAGDFTSDAMARIRSIHEKGHDAIVAGGSTLYIEGLLHGFSQLPKKDADIRRRLQEELNTGGAEKLYARLTTLDPEHARTLDPSKTQRLVRSLEIITITGKTVTGLRAAEHSRLSSVTFIPFGLSLQRNRLYERINTRTDAMMASGLLKEAEQLYERYLSAENRATINALETVGYKELFQYFDGIHSLLRAVELIQQHTRNYAKRQLTFFKNRLNVQWLAAPENLKELHEQKEQLITLYSKT
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TRPB_PSEPW
Sequence: MTQSQYRPGPDANGLFGSFGGRYVAETLMPLVLDLAREYEAAKADPKFLEELAYFQRDYIGRPNPLYFAERLTEHCGGAKIFFKREELNHTGAHKVNNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLLGAEIVPVTAGTGTLKDAMNEALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQSIIGKETRAQLQEKEGRLPDSLIACVGGGSNAMGLFHEFLEDESVKIIGVEAGGHGVNTGKHAASLNGGVPGVLHGNRTYLLQDDDGQITDAHSISAGLDYPGIGPEHAYLHEVKRVEYVSITDDEALDAFHATCRLEGIIPALETSHALAEAIKRAPNLPKDHLMVICLSGRGDKDMQTVMNHMAAQEKQA
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RBL_ASPLA
Sequence: MSPQTETKAGVGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEERGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEEEQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEDMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDYIEKDRSRGIYFTQDWVSLPGVLPVASRGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAVDGGDIIREACKWSP
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PSB28_OSTTA
Sequence: MSVSALQQRFALARSFNASTKRFSKSARRSVVVRAGTTTSIQFVKGQNETAVPEVRLTRSKDGSNGTAFFIFSDPDVFENGQGDITGMFLTDEEGEMSTVDVNAKFVNGKPTGIEARYVMKTEADWNRFMRFMERYAEDNGLGFSKK
What are the official names of this protein?
Photosystem II reaction center psb28 protein, chloroplastic, Photosystem II protein W-like.
What is the protein family that this protein belongs to?
Belongs to the Psb28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: ERIJ_HERER
Sequence: MSTQNYHIVAVPPNEWGHMRPMIAFLARLVAVSLNSVDITVTLIIAESAVAKARTELSIQLAGEGIQSAESRFEVVPTAVHMFWPADAYLPALKATYAEVIKKKEPDFALLESMIHPFFDVVRSSATKPIKVGAWLPVALPSWTSMAPICYIRDDPQAYVKQVETTMAEKGLGYMEAASDAYLSHVNGRVLRIPGFPEMTDYEGFPQEPPVLLPVAMVVDWVFGIRDADILVTSTAQALERQGLQVFSKWLKEQPKHSDILAVGPLTSQRTPEVARKEKEEADAGGFTAFLDAWAAKKGPKSVLYICFGSVLLPAEIEHLYAVMRVLLELQIPFIMVLSDAARAALPADLAAAVRDSGLVKLTPWAPQQYILAHAAVGWFLSHCGINGTLESLCLRVPMVCWPLFADQPVLSILVAQVYGCGYELGEVRKGFGLKYRASTGKTPGGTVEDVTREAREVFSKAFFNKAERAKVDANLEKMATELNAAWDAEGDARASALALLDFIRK
What is the function of this protein?
UDP-glycosyltransferase; part of the gene cluster that mediates the biosynthesis of erinacines, cyathane-xylosides that show unique biological activities, including leishmanicidal activity, stimulating activity for nerve growth-factor synthesis, and agonistic activity toward the kappa opioid receptor (PubMed:31535864).  The geranylgeranyl diphosphate (GGPP) synthase eriE catalyzes the first step in erinacines biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:31535864).  GGPP is then substrate of the diterpene cyclase eriG for the production of cyatha-3,12-diene (PubMed:28371074).  EriG is unable to use geranyl diphosphate (GPP) or farnesyl diphosphate (FPP) as substrates (PubMed:28371074).  The cytochrome P450 monooxygenase eriI then hydroxylates cyatha-3,12-diene at C-14 of the seven-membered ring to produce erinacol, which is further hydroxylated at C-15 by the cytochrome P450 monooxygenase eriC to yield cyathadiol (PubMed:31535864).  The cytochrome P450 monooxygenase eriA then catalyzes C-11 hydroxylation in the presence of the short chain dehydrogenase/reductase (SDR) eriH, which leads to the production of cyathatriol (PubMed:31535864).  The acetyltransferase eriL converts cyathatriol into 11-O-acetyl-cyathatriol (PubMed:31535864).  The SDR eriH catalyzes further oxidation of 11-O-acetyl-cyathatriol into 1-O-acetylcyathin A3 (PubMed:31535864).  Finally, the glycosyl transferase eriJ tranfers xylose from UDP-xylose onto C-14 of 11-O-acetyl-cyathatriol to form eracine Q (PubMed:31535864).  EriJ is also able to convert 11-O-acetyl-cyathatriol to eracine Q2 by using UDP-D-glucose as cosubstrate, but at a lower rate (PubMed:31535864).  In the absence of eriL and eriJ, the SDR eriH is able to convert cyathatriol to cyathin A3; this is likely a switching mechanism in the biosynthesis of cyathins (C-14 ketogroup)and erinacines (C-14 glycosylated group) (PubMed:31535864).  The roles of the SDR eriB, the polyprenyl transferase eriF and the dehydrogenase eriK have still to be identified (Probable).
What are the official names of this protein?
UDP-glycosyltransferase eriJ, Erinacine biosynthesis cluster protein J.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: PROB_STRPI
Sequence: MKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAMLHEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSAQVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLAFYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKGRVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_ECO5E
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MAMB5_DENJA
Sequence: RPSFCNLPVKPGPCSGFFSAFYYSQKTNKCHSFTYSGCRGNGNRFRTIEECRRTCVG
What is the function of this protein?
Interacts with vasopressin V2 receptor (V2R/AVPR2), probably in a selective manner (PubMed:35122240).  Inhibits vasopressin binding human V2R in the nanomolar range (Ki=3. 50 nM), and also potently inhibits vasopressin-induced cAMP production (IC(50)=21 nM).  In vivo, intraperitoneal injection of this protein into rats increases diuresis by 6-fold, without any loss of electrolytes (PubMed:35122240).
What are the official names of this protein?
Mambaquaretin-5, MQ5, Upsilon-Dj2a.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
Protein: YABR_BACSU
Sequence: MSIEVGSKLQGKITGITNFGAFVELPGGSTGLVHISEVADNYVKDINDHLKVGDQVEVKVINVEKDGKIGLSIKKAKDRPQARPRNDFRPKESFEQKMNKFLKDSEDRLSSLKRNTESKRGGRGARRG
What are the official names of this protein?
Uncharacterized protein YabR.
What is the protein family that this protein belongs to?
Belongs to the peptidase U57 family.
Protein: OCT7_ARATH
Sequence: MADGNTRFTVDEALVAMGFGKFQIYVLAYAGMGWVAEAMEMMLLSFVGPAVQSLWNLSARQESLITSVVFAGMLIGAYSWGIVSDKHGRRKGFIITAVVTFVAGFLSAFSPNYMWLIILRCLVGLGLGGGPVLASWYLEFIPAPSRGTWMVVFSAFWTVGTIFEASLAWLVMPRLGWRWLLAFSSVPSSLLLLFYRWTSESPRYLILQGRKAEALAILEKIARMNKTQLPPGVLSSELETELEENKNIPTENTHLLKAGESGEAVAVSKIVLKADKEPGFSLLALLSPTLMKRTLLLWVVFFGNAFAYYGVVLLTTELNNSHNRCYPTEKQLRNSNDVNYRDVFIASFAEFPGLLISAAMVDRLGRKASMASMLFTCCIFLLPLLSHQSPFITTVLLFGGRICISAAFTVVYIYAPEIYPTAVRTTGVGVGSSVGRIGGILCPLVAVGLVHGCHQTIAVLLFEVVILVSGICVCLFPFETSGRDLTDSISASKEPPSASV
What is the function of this protein?
High affinity carnitine transporter involved in the active cellular uptake of carnitine.  Also transports organic cations (By similarity).
What are the official names of this protein?
Organic cation/carnitine transporter 7, AtOCT7.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SASH3_BOVIN
Sequence: MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDESSVPTPEDAEKSGKKLGKKWRAVISRTMNRKTGKKMVKALSEEMGDTLEEGSASPTSPDCSLDSPGPEKMALAFSEQEERELPALSRQASTGSELCSPSPGSGNLGEESTAPQYTGPFCGRARVHTDFTPSPYDRDSLKLQKGDVIQIVEKPPVGTWLGLLNGRMGSFKFIYVDVLPEEAVGPARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGTESGQEPAVSTVADPKVDIPRDSGCFEGSESGRDEAELAGTEEQLHGLSLSGAP
What is the function of this protein?
May function as a signaling adapter protein in lymphocytes.
What are the official names of this protein?
SAM and SH3 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the SASH family.
Protein: RL7_PSYIN
Sequence: MSITKDQIIDAVAELSVMEVVELITAMEEKFGVSAAAAVAGAAGPAEVVEEQTEFDVIMTTFGENKVKAIKAVRAATGLGLKEAKDAVESCPVAIKEGISKADAEALKAVLEEIGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: TPIS_CAMC5
Sequence: MKFLANLKCNHTRASFAEYAKILDANLSADDDVSVFVPFTAFDAKEHKFKLGAQNFYPCVSGAFTGEIGKAQLDEFGISSVLIGHSERREILGESERLLRAKFDFAAKNGWQIIYCVGENLSVNEAGGTKEFLRTQLGNIDTGYANLIVAYEPIWAIGTGKSASAEQIAEILGFLRTLTLAPLLYGGSVNAANIGEIARIRECGGVLVGTASWDATNFLNLIASSRERI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YBT9_YEAST
Sequence: MLVSGCSISTNGFIMTEPDPISPSATNFIVSLVIMILIESLNWDKSRTILENSEDGNDRVESYCNSSIFKKSASISINFREYSAIRSFLVSSNNKMMESGVLSAISVNVSVLLPQRRILLSEVRSIPNVTGWSHLYSWKASTPISKETNRTLESSTACAMIPSSLHWKLTNWTQSLKPSIILLKRDASSNFASNIFSLF
What are the official names of this protein?
Putative uncharacterized protein YBR089W.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MUKF_SALA4
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALRDDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: FADJ_ECO57
Sequence: MEMTSAFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIKQLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEALARQGQQLMAEIHALPIPVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEAAVELAKKDRPSSRPLPVRERILAGPLGRAQLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGELAMTPQSQALRSIFFASTEVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGIPVRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLIIEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSPVEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIRMLTEGERVAHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVSSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVMLMLNEAVRCVDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLATQYGSRFTPCERLVEMGARGESFWKTTATDLQ
What is the function of this protein?
Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA.  Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O2AK2_HUMAN
Sequence: MNISDVISFDILVSAMKTGNQSFGTDFLLVGLFQYGWINSLLFVVIATLFTVALTGNIMLIHLIRLNTRLHTPMYFLLSQLSIVDLMYISTTVPKMAVSFLSQSKTIRFLGCEIQTYVFLALGGTEALLLGFMSYDRYVAICHPLHYPMLMSKKICCLMVACAWASGSINAFIHTLYVFQLPFCRSRLINHFFCEVPALLSLVCQDTSQYEYTVLLSGLIILLLPFLAILASYARVLIVVFQMSSGKGQAKAVSTCSSHLIVASLFYATTLFTYTRPHSLRSPSRDKAVAVFYTIVTPLLNPFIYSLRNKEVTGAVRRLLGYWICCRKYDFRSLY
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 2AK2, Olfactory receptor 2AK1, Olfactory receptor OR1-47.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.