PharMolix/UniProtQA huggingface dataset:
Protein: MTM9L_BOVIN
Sequence: MEFAEMIRTGQAQAELLRGPEEPPLRGTLCITGHHLLLSPGPQATPDLWLLLLRNVDSIEKRVAGDSGTITLRCKDLRVLQLDIEGVEATLDIARSIEALSSLESVITSFPFFYRPKGLRLGDAWHFHPPECYYKRVARETNAWRLSEANEDFSLCPSYPRAVIVPRAVDDSAVARSARFRQGGRFPVLSYYHAPSGTVLLRAGQPLTGPQKRRCSEDEELLRAVLAGARPGARGFIVDTRSPQAAKQARMTGGGTEAKAAYPGWKRLHRPLERGRPLQESFVRLVEACGDLEQSMDRWLNRLESCRWLSHVKETLSTACLAAQSMEQEGACILVHGAEGTDSTLLITSLAQLILDPLSRTMAGFQELIEREWVQAGHPFQLRCAHSAFSHARPKHEAPTFLLFLDCVWQLGRQFPLSLEFGEGMLLALFDHAYASPFGTFLCNNEKERCLCEVRTRTHSLWSGLSQPKEQRKLRNPLYVPNPLAIWPSAEPQSLRLWQGLFLRGTRPPEPSEVAWEKVWQIVTDQEKTEGSQPTDSASEPGP
What is the function of this protein?
Probable pseudophosphatase.
What are the official names of this protein?
Myotubularin-related protein 9-like, Inactive phosphatidylinositol 3-phosphatase 9-like.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Protein: RL29_YERPP
Sequence: MKAQELREKSVEELNTELLNLLREQFNLRMQAASGQLQQTHLLKQVRRNVARVKTLLTEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PYRH_BUCAI
Sequence: MSTDKKFIYRRILLKISGEVLQGVNKFGIDINSLKRIAKEIEFIVKIGVQVGLVIGSGNLFRGAKLSKLGLNRVASDHIGILSTVINSLAMRDTINSISSIKTCLMSAIPLNGICEIYNYEKAMNLLSNHVVVIFSAGTGNPFFTTDSAACLRGIETESDIILKGTKVDGVYSKDPNKDSHAFLYRRLTYKDVLKKELKIMDLAAFTLARDYHMPIRVFNIHTPGSLYRIIMGDDEGTLITR
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGTT_ECOLI
Sequence: MNGDNPSPNRPLVTVVYKGPDFYDGEKKPPVNRR
What are the official names of this protein?
Protein MgtT.
Protein: NDUS8_MOUSE
Sequence: MYRLSSSMLPRALAQAMRTGHLNGQSLHSSAVAATYKYVNKKEQESEVDMKSATDNAARILMWTELIRGLGMTLSYLFREPATINYPFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRADGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYNKEKLLNNGDKWEAEIAANIQADYLYR
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (By similarity).  Essential for the catalytic activity and assembly of complex I (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, Complex I-23kD, CI-23kD, NADH-ubiquinone oxidoreductase 23 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: FUT1_SAIBB
Sequence: MWPRSHRHLCLAFLLVCVLSAISFLIHFHQDSIRHGLGLSVLCPDRRLVTPAVAIFCLPGTPMSPNTSSSCPQHPASLSGTWTIYPDGRFGNQMGQYATLLALAQLNGRRAFILPAMHAALAPVFRITLPVLAPEVDSRTPWQELRLHDWMSEEYADLGDPFLKLSGFPCSWTFFHHLREQIRSEFTLHDHLREEAQSVLRRLRLGRSGARPRTFVGVHVRRGDYLQVMPQRWKGVVANSAYLREAMDWFRARHEAPVFVVTSNGMEWCRENIDASKGDVMFAGDGQEASPWKDFALLTQCNHTIMTIGTFGFWAAYLAGGDTVYLANFTLPDSEFLKIFKPEAAFLPEWVGINADLSPLWPLAEP
What is the function of this protein?
Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose residue of glycoconjugates through an alpha(1,2) linkage leading to H antigen synthesis that is an intermediate substrate in the synthesis of ABO blood group antigens.  H antigen is essential for maturation of the glomerular layer of the main olfactory bulb, in cell migration and early cell-cell contacts during tumor associated angiogenesis (By similarity).  Preferentially fucosylates soluble lactose and to a lesser extent fucosylates glycolipids gangliosides GA1 and GM1a (By similarity).
What are the official names of this protein?
Galactoside alpha-(1,2)-fucosyltransferase 1, Alpha(1,2)FT 1, Fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, Type 1 galactoside alpha-(1,2)-fucosyltransferase FUT1, Type 2 galactoside alpha-(1,2)-fucosyltransferase FUT1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 11 family.
What are the subcellular locations of this protein?
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Protein: SAMKB_DICDI
Sequence: MDSTFDARASNKSYLGSNSIALTKNFEDWNNEAVCEWLSENNFKMSDIEKFQENKIKGDHLEFIGDKILIQMGLSIYERLSFKSIFKKLKNNNKIKIDSTDNYKNECESNSINNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKIDTFNSSIKQLNFSQEANDPNIKAPILDINQYKLIEEIGRGAFSIVEKYENKLKPNEFISIKRINVLASEKEMIVKEINMLYSINHPNIIKIIGYYKDEHYYYIATPYYKKGSIAKIVKSIKSKNNSGFSESNVRNISKKILNAIDYLHSSNPPIVHRDIKGDNILLNDSDEPILADFGLSYLAIENNTNFKTACCSPFWAAPEILNKSTSDFSRKCDIYSFGCTILEMIVGSDPWGGKRNHQSHSPPIPTYLTLECKEVLNETLKYNQNFRADSKQLLEAQWFKETSLRNSSNGEIIFSSEDIMKEFKKNGSTIQIGPVKQEYKYKEQFDIENISKWPREPSFIDPKHKNYKEVLNLYDHYINHSPFMAKIGPYVLDLKEELNEKTFYKSLAISSILGKIDKYEPTTNQNLIPSLFFGFINFVLYQTIKHYPSKFRIL
What are the official names of this protein?
Probable serine/threonine-protein kinase samkB, SAM domain-containing protein kinase B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ENO_ARCFU
Sequence: MIIEDVHYRVVFDSRGNETVECEVVAGEVVAKAMAPSGASTGSGEAVVVSPYRYEEIEEEVSKAIIGMSVFDQESVDEALRELDGTDNFSRIGGNFAITASLAVAKAAAEILGLPLYAYVGGVFAKELPYPLGNVIGGGRHAEGSTSIQEFLVIPVGAKTFFEAQRANAAVHKQLKKIFKERGIFAAKGDEGAWAAQISDEQAFEILSEAIQRVEDELGVKVRMGIDVAATELWDGERYVYSDRKLTTEEQIAYMAELADRYDLLYIEDPLHEKDFEGFAELTKQVKCMVCGDDIFVTNPEIIKKGIEVGAANTVLIKPNQNGTLSGTAKAVKIAKDNGYSVVVSHRSGETEDETLAHLAVAFNAKLIKTGVVGGERISKLNELIRIEELMDKPRMVMI
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: ATPA_MYCBO
Sequence: MAELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSVPVGDGFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKKQVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAASESAGFKWLAPYTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITDGQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQYRELEAFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEEEILTEIRDSQKLTEEAADKLTEVIKNFKKGFAATGGGSVVPDEHVEALDEDKLAKEAVKVKKPAPKKKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CWP33_TOBAC
Sequence: SPPAPFVPVPIN
What are the official names of this protein?
26 kDa cell wall protein.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: XGPT_ECO7I
Sequence: MSEKYIVTWDRLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IL10_SAISC
Sequence: MHSSALLCCLVFLTGVRASPGQGTQSENSCTHFPGSLPHMLRELRVAFGRVKTFFQKKDQLDSMLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENHDPDIKEHVNSLGEKLKTFRLRLRRCHRFLPCENKSKAVAQVKNAVSKLQEKGVYKAMSEFDIFIDYIEAYMTMKTQN
What is the function of this protein?
Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation.  Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3.  In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators.  Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha.  Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity).  In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
What are the official names of this protein?
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_THEPO
Sequence: SVGFKAGVKEYKLTYYTPEYEVKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVLGEEDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPIAYVKTFEGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMMKRAVCARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKAIKFEFDAVDNL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y100A_AFV2P
Sequence: MPLDNSFPLSQLSKVSERVLEIHLELLDTKSKLNDIYKDICELQRFTEQLINDDDLRESYVSSKPELSKNWEKLKKEIEQKHKEIQELISEFDNMFINSF
What are the official names of this protein?
Uncharacterized protein ORF100a.
Protein: GPI11_SCHPO
Sequence: MGFWGRNSFEADKKHILVTGGSQGLGKAIAKELVLRGANVTIVARTVTKLQEAVAELSDSKIHEDQQVSFESVDLTSYESVHSMIERLPFCPDHVVHCAGSCIPGFFTELDPSVFEKQMRQNYLASVYVCHAAIRRMKEISPSYSRRILLVGSLLSSLPIIGYSAYSPVKAAVRNLADSLRQECILYDIEVSVYLPSTILSPGYEQENTLKPELVLQMEGMDSVQTCEEAASHCMTGLDRGDFLIANESTGHLMKNHCRNSSPHDNPILEYLFALVSLLAWPFYRRKLDSLVYQYALEKGYRQPSSSRNSWIFTLLLTFTQLTIFYLSLNCLIENPYRMLRNTFPIWFIMQTLQIYIQSPRPPLTPKRLLAGAASMLIGSLLISFILVAFGAPLLHDFHLTYFCALTLSVFTVYPLASTLAFNTEQWQRFLTLKSFNVIGSMQLRSWGPIIGAWFGAFPIPLDWDRPWQAWPITIVIGAFLGYAFAAIVGEILQ
What is the function of this protein?
Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
What are the official names of this protein?
PIGF/3-ketodihydrosphingosine reductase fusion protein, 3-ketodihydrosphingosine reductase, PIGF homolog.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PIGF family.
Protein: LOLB_FRATF
Sequence: MSKLKIDTKRRFSLLIALVLIISLSSCATTQTNVTAITTKTVFNQETTYHNLLKLKKWQANGFIGIIYDNQAESANYTYLQDGDNFSIKLYGPLGIGSIEIKGDTNSVSLANSKGQKLTAKDAKTLMLEQLGWYVPVEGLKYWIKAIAIPNIRQTSELNTNNLLSKLSQNGWSISYSNYQLVDSKYPLPTKIRMSRDNLTLKIVIKSWQI
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y2205_BURP6
Sequence: MMKGQLAGLMKQAQQMQENMKKMQEQLALIEVEGQSGAGLVKVTMTCRNEVRRVAIDPSLLADDKDMLEDLVAAAFNDAVRKAEATSQEKMSGMTSGLPLPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BURPS668_2205.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PEPA1_MACFU
Sequence: MKWLLLLGLVALSECIIYKVPLVRKKSLRRNLSEHGLLKDFLKKHNLNPASKYFPQAEAPTLIDEQPLENYLDVEYFGTIGIGTPAQDFTVIFDTGSSNLWVPSVYCSSLACTNHNLFNPQDSSTYQSTSGTLSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFDGILGLAYPSISSSGATPVFDNIWDQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGSLNWVPVSVEGYWQISVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGASENSDGEMVVSCSAISSLPDIVFTINGIQYPVPPSAYILQSQGSCTSGFQGMDVPTESGELWILGDVFIRQYFTVFDRANNQVGLAPVA
What is the function of this protein?
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
What are the official names of this protein?
Pepsin A-1, Pepsin III-3.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PNP_ACIC5
Sequence: MKQDVTVELTGGKKLHFETGRMAKQASGAALVTQGESVVLATAVAAPDPKEGIDFFPLTVDYREYAYAGGRIPGGFIKREGRPSEREILTSRQIDRPIRPLFPEGFRNETQVIALVFSADKENDPDIVGINAASAALALSDIPFAGPVGAVRVGYVNGEYVINPSYAERRDSSINITVVGTMDGIVMIESGSAEVPEEVVLGAIDFGHTEIKKIVAAINELAAKAGKTKRAVTAPEFDEAYFETLKNKIGARLADALDTKAHPKTESYALVKQIKDELAAEIPADENAGAAKKKLAHYYELLREKIFREQVTKDRVRPDRRGFDEIRQITIEVGVLPRTHGSALFTRGETQALVTATLGTNDDSQRLETFEGEQKKRFMLHYNFPPFSVGEVGRMTGVGRREVGHGALAERAISAVLPGEDESPYALRVVSDILESNGSSSMASVCGASLALMDAGIPLKGAVAGVAMGLVKEGDEYAILTDIAGAEDHYGDMDFKVAGTRKGITALQMDIKISGITGQIMREAMEQARRGRMFLLDKMDEILAAPREEKSKHAPQIRTVQIPTDKIRDLIGPGGKTIRGIIEATQVKIDVDDTGRVNIASSDEEGLKKALAMINDLTAVPEVGKTYLGKVVRLAEFGAFVEIFPGTDGLLHISEIAEHRVKEVKDELHEGDQVMVKVLGVEGNRIKLSRKAVIREQRQKLGLPEPGAEAPAAAEGQPRAERAERQPSSNASTITIEGGEDFDDFDEEGGEGEGEDENFNREDTPNSAPGERRPGGAGAAGNRGRRRRRGRGRGPGQGGGGNRGPQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRXH_POPJC
Sequence: MGLCLAKRNHDADDDEPHIELAGGNVHLITTKERWDQKLSEASRDGKIVLANFSARWCGPCKQIAPYYIELSENYPSLMFLVIDVDELSDFSASWEIKATPTFFFLRDGQQVDKLVGANKPELHKKITAILDSLPPSDK
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide.  The H form is known to activate a number of cytosolic enzymes (By similarity).
What are the official names of this protein?
Thioredoxin H-type, Trxh4.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family. Plant H-type subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGD_SALTY
Sequence: MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLEKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKDAYELVAPILTKIAAVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLSNEELANTFTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKAQRVAASKVLSGPKAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASDEYHWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENADIANLLLAPYFKKIADEYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRTDKEGIFHTEWLE
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
Protein: EFG_STRS2
Sequence: MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHERLQANAHPIQLPIGSEDEFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLEQAEEYREKLVEAVAETDEELMMKYLEGEEITNDELKAAIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGVNPDTDAEEERHASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKIILESIHVPEPVIQLMVEPKSKADQDKMGIALSKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPIVDVKAKLYDGSYHDVDSSETAFKVAASLALKEAAKSAQPTILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEARGNTQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQDEIIKKNGGNA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCRA_LIMPO
Sequence: MARYRKPERVTRVISGSDEYVDFKKIDEEPTDKLDPNLGIIKSMPKLEPEEINDTLLRQTNLRSFKPGLSAVNDLDNESTPVVLAFGGINTARPDEYLNSSSVFVYHPDRNKWNFYTTMMEPRTYHAVGYFHRRVYVFGGYNPLHCRKGKMQATATTFQLTVQTKQWRKRADMRYARAHHNVTVMDERIFVFGGRDSNGEILAAVEMYEPEMDQWTTLASIPEPMMGSAIANNEGIIYVIGGVTTNKEKKPEGNLSNKIFCFDPLNNKWYRKPSLSSPRAFSAATTQNKKIWIWGGANLSEEGLLSSIDSIDVLDPKKGTLEHHMNFELAKHCHAVAKTGAHVFIVGGMSSVEASAIAETEMYDRKRNIIQRCSLLPVALTGIAVAAIPADTGGEYYEVPTSTPSSKAKPQPGSKPTSVKYKKQPDIHERNEAAKKVQRRWRRYIEQKSITKRMQQGDSSGSTMLEGNDRISGRIRTYISGYRPLPPDQDDLSKELVPVSIPFWPPDPDTTDSVFHTVRDQYRNPEEQMGFKHFYTIPRQMDPNLGMLLFMDEDYQHSKKVLGLRSVESVPYYINRFQASGTIQDNTIPVIIGTGGVDLRDPMNIAYGRSVFQYHPLKDRWEFFGYMPQPRNYHAAAYYRSAIYITGGYDPDVRTWGEMVATKTTFVYELASKNWTRMGDMRCARSHHSLLVFNDVLYAIGGRDDIGRLVSSVESYDHESNEWTMEKSMPSPRMGMAAVAHGGYIWLLGGLTSMTTEEPPVLDDVLCYDPVFKHWVDGRPLRIGRAFGNAAVCDNKIWLCGGAAPSTDENNYLVSVPAIDVYDEETMEWKQKTSLGCPRHSAIVVALESCLYIAGGVNSHELSATSRNELYMVDNDTIQTVRELPIPLTGMAAVTIPPKCVTFRSESLSIMIRHKVTP
What is the function of this protein?
Actin bundling protein found in the acrosomal sperm process.
What are the official names of this protein?
Alpha-scruin.
Protein: MSHR_SEMEN
Sequence: MPVQGSQRRLLGSLNSTPTATPRLGLAANQTGARCLEVSIPDGLFLSLGLVSLVENVLVVVAIARNRNLHSPMYCFICCLALSDLLVSGSNMLETAVILLLEAGALAARAAAVQQLDNVIDVITYSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLRRAWRVVAAIWVASVLFSTLFIAYCNHAAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIAQLHKRQRPAHQGVGLKGAATLTILLGIFFLCWGPFFLHLTLVVLCPQHPTCSCIFKNFNLFLTLIICNAIIDPLIYAFRSQELRRTLKKVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TFB3_CANGA
Sequence: MSSAVASKGMNQGSEFDDNKDMCPICKTDRYLSPDVRFLVNPECYHKICESCVDRIFSLGPAPCPYKSCDKILRKNKFKTQIFDDVGVEKEVDIRKRVFNVFNKTLEDFDNDLEAYNKYLEEVEDIVYKLDNKIDVVETEEKLRTYEELNKQLIMNNMERSKKDLENFEQRQQFEKEMRMKKRMLERQIESEDKMNKEWAKREIVNRLASSTNADDVIEGVKNTVKLKKSSARRKLEEINRVLQNNPYSSLMLSQGLSRKEDNVPFTPFNGDRDLDKRYTIDQESYDDPFIKDLENRKDYIASGFRSDFVYDRMLTEAFMGLGCVVAEEV
What is the function of this protein?
Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.  TFIIH as CTD kinase activity and DNA-dependent ATPase activity, and is essential for polymerase II transcription (By similarity).
What are the official names of this protein?
RNA polymerase II transcription factor B subunit 3, RNA polymerase II transcription factor B 38 kDa subunit, RNA polymerase II transcription factor B p38 subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL27_ANAMF
Sequence: MATKKSGGSSSNGRDSRGRRLGVKKFGSELVIPGNIIIRQRGTRYHPGRNVGMGKDHTIFSKIAGVVCFRKRTGGKVFVDVVPQSCLSSV
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: AGLK_METVO
Sequence: MADKLIYLIIPAYNEEKMIKNVVNNLQNHNYDNIIIVDDGSKDNTYKIMKELEEESKQNNNNNNNNNNNKVIAIKHEQNKGVGGATITGLKKAYELGADIAVTFDADGQHAPDDIAKVIQPIINDSKEYVVGSRIKNPKEFKNMPLTKKVGNLGLSFITFLLGGYYVTDSQSGLRAFSKSALKVLSEQLRAKRYETCSEALIIAKKNKLNIGEVPIKTIYTEYSMARGTNVMIGFKIFYRLLMLKMGKVLD
What is the function of this protein?
Involved in the assembly of an N-linked disaccharide that decorates the S-layer glycoprotein and flagellins (PubMed:18978056).  AglK initiates N-linked glycosylation through the formation of alpha-linked dolichyl monophosphate N-acetylglucosamine.  It catalyzes the transfer of GlcNAc from the donor substrate UDP-GlcNAc to dolichyl phosphate C55 (Dol-P) to yield Dol-P-GlcNAc (PubMed:23624439).  AglK reaction proceeds with retention of stereochemistry (PubMed:23624439).  The reaction is specific for UDP-GlcNAc.  AglK shows a stronger preference for short dolichol (C55-60 Dol-P) substrates compared with the longer (C85-105 Dol-P) (PubMed:23624439).
What are the official names of this protein?
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminyltransferase, Dol-P-GlcNAc synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.