PharMolix/UniProtQA huggingface dataset:
Protein: ATPB_NEIM0
Sequence: MSQGKIVQIIGAVVDVEFPRDMIPRVYDALKLDENGLTLEVQQLLGDGVVRTIAMGSSDGLKRGMTVSNTGAPITVPVGKGTLGRIVDVLGTPVDEAGPIDTDKSRAIHQAAPKFDELSSTTELLETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEYFRDEKDENGKGRDVLFFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTQTGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPMVLGQEHYDVARGVQSTLQKYKELRDIIAILGMDELSDEDKLTVMRARKIQRFLSQPFHVAEVFTGSPGKYVALRDTIAGFKAILNGEYDHLPEQAFYMVGSIEEAVEKAKTLN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YAAI_SHIF8
Sequence: MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: METXS_ACIF5
Sequence: MPVEIPADSVGLVTPQTVTFSAPLELECGRSLPGYTLTYETYGTLNAQRSNAILLCHALSGDHHAAGYHSMDDRKPGWWEHLLGPGKAMDTERFFFVCANFIGSCKGSTGPASTNPETGAPWGLDFPMVTVRDWVKTQAELADYLGIEQWAAVVGGSLGGMQVMQWSMDYPERLRHAVVIAAAPKLTAQNIAFNEVCRQAIMTDPEFYNGRYYAHNTKPRRGLSLARMIGHITYLSDNAMRTKFGRDTRGGKAFSFGFDVDFEVESYLRYQGSSFVERFDANSYLYITKALDYFDPASTWGGNLAEAFASTRANFLVISFSSDWRFSPERSREIVQALYTCNRDVSYAEIEAEHGHDSFLMPIPQYVAVLSTYLGRVAEEIGA
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURNU_UNKP
Sequence: MIELEKLDFAKSVEGVEAFSTTRGQVDGRNAYSGVNLCDYVGDDALRVLDARLTLAMQLGVDLDDLVMPRQTHSCRVAVIDERFRALDIDEQEAALEGVDALVTRLQGIVIGVNTADCVPIVLVDSQAGIVAVSHAGWRGTVGRIAKAVVEEMCRQGATVDRIQAAMGPSICQDCFEVGDEVVEAFKKAHFNLNDIVVRNPATGKAHIDLRAANRAVLVAAGVPAANIVESQHCSRCEHTSFFSARRLGINSGRTFTGIYRK
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine (By similarity).  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate (By similarity).  Also has adenosine deaminase activity (By similarity).  Also acts as a multicopper oxidase able to oxidize a wide variety of polyphenols and related compounds in vitro (PubMed:16740638).  Displays substrate preference as follows: syringaldazine > 2,6-dimethoxyphenol > veratryl alcohol > guaiacol > tetramethylbenzidine > 4-methoxybenzyl alcohol > 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) >> phenol red > 1-hydroxybenzotriazole (PubMed:16740638).  Cannot use 3,4-dimetoxybenzyl alcohol and violuric acid as substrates (PubMed:16740638).  As this enzyme is derived from a rumen microbial community, it may have a role in the digestion of complex plant materials such as ryegrass lignin (PubMed:16740638).
What are the official names of this protein?
Adenosine deaminase RL5, Laccase RL5, Multicopper oxidase RL5, Polyphenol oxidase, Purine nucleoside phosphorylase RL5, S-methyl-5'-thioadenosine phosphorylase RL5.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: ATPL_SALPB
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACA2_ARATH
Sequence: MESYLNENFDVKAKHSSEEVLEKWRNLCGVVKNPKRRFRFTANLSKRYEAAAMRRTNQEKLRIAVLVSKAAFQFISGVSPSDYTVPEDVKAAGFEICADELGSIVESHDVKKLKFHGGVDGLAGKLKASPTDGLSTEAAQLSQRQELFGINKFAESEMRGFWVFVWEALQDMTLMILGVCAFVSLIVGIATEGWPKGSHDGLGIAASILLVVFVTATSDYRQSLQFRDLDKEKKKITVQVTRNGFRQKLSIYDLLPGDIVHLAIGDQVPADGLFLSGFSVVIDESSLTGESEPVMVNAQNPFLMSGTKVQDGSCKMMITTVGMRTQWGKLMATLTEGGDDETPLQVKLNGVATIIGKIGLFFAVVTFAVLVQGMFMRKLSTGTHWVWSGDEALELLEYFAIAVTIVVVAVPEGLPLAVTLSLAFAMKKMMNDKALVRHLAACETMGSATTICSDKTGTLTTNHMTVVKSCICMNVQDVANKGSSLQSEIPESAVKLLIQSIFNNTGGEVVVNKHGKTELLGTPTETAILELGLSLGGKFQEERKSYKVIKVEPFNSTKKRMGVVIELPEGGRMRAHTKGASEIVLAACDKVVNSSGEVVPLDEESIKYLNVTINEFANEALRTLCLAYMDIEGGFSPDDAIPASGFTCVGIVGIKDPVRPGVKESVELCRRAGITVRMVTGDNINTAKAIARECGILTDDGIAIEGPVFREKNQEELLELIPKIQVMARSSPMDKHTLVKQLRTTFDEVVAVTGDGTNDAPALHEADIGLAMGIAGTEVAKESADVIILDDNFSTIVTVAKWGRSVYINIQKFVQFQLTVNVVALVVNFSSACLTGSAPLTAVQLLWVNMIMDTLGALALATEPPNDELMKRLPVGRRGNFITNAMWRNILGQAVYQFIVIWILQAKGKAMFGLDGPDSTLMLNTLIFNCFVFCQVFNEISSREMEEIDVFKGILDNYVFVVVIGATVFFQIIIIEFLGTFASTTPLTITQWIFSIFIGFLGMPIAAGLKTIPV
What is the function of this protein?
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the endoplasmic reticulum.
What are the official names of this protein?
Calcium-transporting ATPase 2, plasma membrane-type, Ca(2+)-ATPase isoform 2.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SYE_META1
Sequence: MNKTIRTRYAPSPTGYLHIGGARTALFCYLFAKHSNGDFIFRLEDTDVERNVEGGEASQLNNLAWLGIVPDESPLKPNPKYGKYRQSEKLAIYQAYIDELIKQGLAYKAYDSSEELAKQHEEQEKAGVASFRYDPTWLKLSESEIKRRDEAKEYSIRLKLPKNKNYSWDDLVRGPISVNSDDIGDFVIMKSDGYPTYNFAVVVDDHQMDITHVLRGEEHITNTPKQLAIYEAFGWDNPVFGHLTIITNMEGKKLSKRDKSLKQFIEDYKNEGYCPEAIFNFLALLGWTSGDKTEIMSHDELIKKFDYNRLSKSPSKFDIVKMEWFSKQYMKKLPNEVIIEKINSPKDAQWNNLFVETYKQQAATISEIKENLKIYLFPKEKLELQIDNDLVVKTFFAHLKAKDFTIENIQAAIDETKNALNVKGKDLFMPIRITATYEEHGPELAKAIYLFGKDLVYKRLTKWS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPP2_MAIZE
Sequence: MAALGPKMERLSSIDAQLRMLVPGKVSEDDKLIEYDALLLDRFLDILQDLHGDDLKEMVQECYEVAAEYETKHDLQKLDELGKMITSLDPGDSIVIAKSLSHMLNLANLAEEVQIAYRRRIKLKKGDFADENSAITESDIEETLKRLVVDLKKSPAEVFDALKSQTVDLVLTAHPTQSVRRSLLQKHSRIRNCLVQLYSKDITPDDKQELDEALQREIQAAFRTDEIRRTQPTPQDEMRAGMSYFHETIWKGVPKFLRRVDTALKNIGINERVPYNAPLIQFSSWMGGDRDGNPRVTPEVTRDVCLLARMMASNLYCSQIEDLMFELSMWRCSDELRMRADVLHLSTKKDAKHYIEFWKKVPPNEPYRVILSDVRDKLYNTRERSRELLSSGHSDIPEEATLTNVEQLLEPLELCYRSLCACGDSVIADGTLLDFLRQVSTFGLSLVRLDIRQESDRHTDVLDAITTYLGIGSYREWTEERRQEWLLSELNGKRPLFGSDLPKTEEISDVLDTFHVIAELPSDNFGAYIISMATAPSDVLAVELLQRECHVKTPLRVVPLFEKLADLEAAPAALARLFSIDWYRQRINGKQEVMIGYSDSGKDAGRLSAAWQLYKAQEELIKVAKDFGVKLTMFHGRGGTVGRGGGPTHLAILSQPPDTIHGSLRVTVQGEVIEQSFGEEHLCFRTLQRFTAATLEHGMHPPNAPKPEWRALLDEMAVVATEEYRSIVFKEPRFVEYFRLATPETEYGRMNIGSRPSKRKPSGGIDSLRAIPWIFAWTQTRFHLPVWLGFGAAFKNVLQKDIRNLHMLQEMYNEWPFFRVTIDLVEMVFAKGNPGIAALYDKLLVSEELHPLGEKLRANYEETQKLLLQVAGHRDLLEGDLYLKQRLRLRDAYITTLNVCQAYTLKRIRDPDYHVALRPHLSKEIMDSTKAAADVVKLNPGSEYAPGLEDTLILTMKGIAAGLQNTG
What is the function of this protein?
Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase 2, PEPC 2, PEPCase 2.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_HAEI8
Sequence: MNSRILSTGSYLPSHIRTNADLEKMVDTSDEWIVTRSGIRERRIAAEDETVATMGFEAAKNAIEAAQINPQDIELIIVATTSHSHAYPSAACQVQGLLNIDDAISFDLAAACTGFVYALSVADQFIRAGKVKKALVIGSDLNSRKLDETDRSTVVLFGDGAGAVILEASEQEGIISTHLHASADKNNALVLAQPERGIEKSGYIEMQGNETFKLAVRELSNVVEETLLANNLDKKDLDWLVPHQANLRIITATAKKLEMDMSQVVVTLDKYANNSAATVPVALDEAIRDGRIQRGQLLLLEAFGGGWTWGSALVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_SYNWW
Sequence: MAIKLLNDNVINKIAAGEVIERPASVVKELLENAIDAASRNIAVKISGAGLDSIEVTDDGEGISMEELPLAFLRHATSKIENEGDLLRIMSMGFRGEALPSIASVSRIDIYSKKEKQEGIHCFIEGGKILDLQYFPGPEGSKIIVSDLFFNTPARKKFLRSPVTEGNNAYELVIKYALARPDIAISFSNEKRQLFRTPGNGSLNDAVIAIFGRDFLEPLIPVKWEGLSLSISGLISPPGVAKMNRKRQLIFVNQRPIRSPLLYRALDEGYRGLLLAREQPLVILQIAVPPDSIDVNVHPQKSEIRFRDEQSIFRSLCGLLRDTLNARDYRLQDNLPQNRSQPFYPAAGRKTAKQKVEEQPVIPFMHNRKADKRVEETGGEPWIPFYPEEQAEGSVSRVYDEFKILGQLWDSYILLEKEQTLNIVDQHAAHERIIYSRLQQFYAASRGEMQMLAFPLLMDLSLRDMELLEKNQEILGELGFDLQQAGPRSIFLRGTPAIIAGQEREVLFEILELLAGGQGINLKNEAIIKMACKKAVKAGTRLDYREMMQIIQELFITDDYKNCPHGRPTIIAWKQADLERMFKR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: GPAN1_HUMAN
Sequence: MSRPLLITFTPATDPSDLWKDGQQQPQPEKPESTLDGAAARAFYEALIGDESSAPDSQRSQTEPARERKRKKRRIMKAPAAEAVAEGASGRHGQGRSLEAEDKMTHRILRAAQEGDLPELRRLLEPHEAGGAGGNINARDAFWWTPLMCAARAGQGAAVSYLLGRGAAWVGVCELSGRDAAQLAEEAGFPEVARMVRESHGETRSPENRSPTPSLQYCENCDTHFQDSNHRTSTAHLLSLSQGPQPPNLPLGVPISSPGFKLLLRGGWEPGMGLGPRGEGRANPIPTVLKRDQEGLGYRSAPQPRVTHFPAWDTRAVAGRERPPRVATLSWREERRREEKDRAWERDLRTYMNLEF
What are the official names of this protein?
G patch domain and ankyrin repeat-containing protein 1, Ankyrin repeat domain-containing protein 59, G patch domain-containing protein 10, HLA-B-associated transcript 4, Protein G5.
Protein: RISB_KOSOT
Sequence: MRVFEGRYYGEGLKIAIVISRFNSAVTKELLDGALDALKRHEVKDENIDVIWVPGAMEIPHITRSIALKKKHDAIIALGAVIRGETYHFDVVANEVSKGIAAINLEVDVPVSFGIITSDTVEQALNRAGIKSGNKGFEAAMVALEMANLKRQIEAI
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CRYAA_SHEEP
Sequence: MDIAIQHPWFKRTLGPFYPSRLFDQFFGEGLFEYDLLPFLSSTISPYYRQSLFRTVLDSGISEVRSDRDKFVIFLDVKHFSPEDLTVKVQEDFVEIHGKHNERQDDHGYISREFHRRYRLPSNVDQSALSCSLSADGMLTFSGPKVPSGVDAGHSERAIPVSREEKPSSAPSS
What is the function of this protein?
Contributes to the transparency and refractive index of the lens.  Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.  Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
What are the official names of this protein?
Alpha-crystallin A chain.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Protein: ROT1_VANPO
Sequence: MFGMRLLPFLANAVILFNFAIGDNDAASLSGTWSSKSNQVFTGPGFYDPVDELLIEPALPGISYSFTEDGYFEEAQYRVVANPRNIGCPQAVLIYQHGKYEILTNGTLILTPFEVDGRQLLSDPCNDDGVSTYSRYNQSETFLSFDISIDDYHGIYKLQLNQFDGSPLQPLYLAYRPPMMLPTITLNPTATNDPTDAVGKGSVSKRSLRQIVKRNLENKHKQLATKKYSGILVSPYLWYVCTGVIGVGSALFLFS
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
What are the official names of this protein?
Protein ROT1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: TRPF_HYPNA
Sequence: MAKVKICGLKDPDMVAFAAREGADWVGFVFAPSVRQVTLAAAETLLLSVGKATPVALMVDPSDAEAQAVAALGFPILQLHGQETPARAAELKSLTGCAIWKAIGVQTRDNLGQIGTFPDIDGLLLDAKPPEGATIAGGHGAAFDWSILKGWTAPKPWLLAGGLTPENVAEAIAATGAPGVDVSSGVERIRGLKDRELVRAFIRAAKASEQP
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: ISPG_CHLFF
Sequence: MIISPFKKQTARRYTHSVKIGSLFVGSEHSIKMQSMTTTPTSDVDATVAQICSLVEAKCDIARVTVQGVKEAQACEHIKERLLTMGLDIPLVADIHFFPQAAMHVADFVDKVRINPGNFVDKRNMFSGKTYTDKNYADSLLRLEEKFSPLVEKCKRLGKAMRIGVNHGSLSERIMQRYGDTIEGMVVSALEYIKVCENLGYRDVVFSMKSSNPKVMVAAYRQLAKDLDARGWHYPLHLGVTEAGMGMDGIIKSAVGIGTLLTEGLGDTIRCSLTGCPTEEIPVCESLLKHTTIYLNLPKQENPFALENSESFVNASKKITKTTPWGSVYGVFIKLHEHHILNTTAERLLEQLGINPTNGKKDATAPEGVVIPKSFLGTSIIEKLQKHMSVFHHHEVPCLYDYNEEIWNNEQVLSAPFVHCHATPPFIHSVRSFFSKRQCEDQPVKLVFSKDLDDEYEATVSIATEFGALLLDGLGEGVILDLPNIPLPTVREIAFGTLQSAGVRLVKTEYISCPGCGRTLFDLPEVTTRIRNKTKHLVGLKIAVMGCIVNGPGEMADADFGFVGSKTGMIDLYVKHTCVKAHIPMEDAEEELFRLLQEHGVWKDPE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: BPPCE_BOTCO
Sequence: QARPRPGPKIPP
What is the function of this protein?
This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it.  It acts as an indirect hypotensive agent (By similarity).
What are the official names of this protein?
Bradykinin-potentiating peptide 12e, BPP-12e.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL2_HALS3
Sequence: MGRRIQGQRRGRGTSTFRAPSHRYKAELSHKRTEDTDVLAGEVIDVEHDPARSAPVARVAFEDDDQRLVLASEGVGVGDTIEIGISATIEEGNTLPLAEIPEGVPVCNVESHPGDGGKFARAGGVNADLVTHERDATIVELPSGETKRLSPDCRATIGVVAGGGRTEKPFVKAGNKHHKMKARGTKWPRVRGVAMNAVDHPFGGGGRQHPGRPKSVSRDAAPGRKVGDIASKRTGRGGNE
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CBIJ_SALTY
Sequence: MNEGDVLVVGGTSDARALCRQLDAANVAYTLSVATPAGKALAGDIKGQVRCGRLEYGQMVAWLKENRTRWVIDASHPYAEMVSHNLLRACETAGVLLSRYQRPEQLSNLTHPLLYTARSIADACEIARRFGPRVLLTTGSKDLAVWRAGLAEKTLLARVLPVAEVIQRCSELGFGVGEIFALCGPFSADFNAAFYHQCRADVVITKASGAEGGYQEKVQPCLDAGIPCIVIARPTPLVTGDELLESQAAFAQRLSRWLAAAKE
What is the function of this protein?
Catalyzes the reduction of the macrocycle of cobalt-precorrin-6A to cobalt-precorrin-6B.
What are the official names of this protein?
Cobalt-precorrin-6A reductase.
What is the protein family that this protein belongs to?
Belongs to the precorrin-6x reductase family.
Protein: SYK_PROM0
Sequence: MSEIKEARLQKASSLVSKGFASYAQSFRVSHTTSFLIQKFDYLENGQEENFSVSLAGRVMAKRVMGKIAFFTISDQDGQIQLYLEKRIINLNLEKQKLLSFEDIKEIVDIGDWIGVYGTIKKTNKGELSIKVEKWEMLSKSLQPLPDKWHGLTDIEKRYRQRYLDLIVNPHSKNVFKTRAKCISFIRKWLDNRNFLEIETPILQSEAGGAEARPFITHHNTLDIPLYLRIATELHLKRMVVGGFEKVYELGRIFRNEGISTRHNPEFTSVEIYEAYSDYVDMMNLTEELIKDILADACGSLTINYQNKEIDFSKPWLRISMKDIVKKYTGIDFHSFNGDFLAAKKAVKNINVDFSNKVNTIGRLLNEVFEQKVESKLIEPTFVIDYPVEISPLARPHFDNKEIVQRFELFIVGRELANAFSELIDPVDQRERMQLQQSLRDKGDLEAHCIDEDFLNALEIGMPPTGGLGIGIDRLIMLITNSASIRDVIPFPLLKPEISSKKSEKLPLNEVK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NASP_RAT
Sequence: MATESTATAAIAAELVSADKVEDAPAPSTSADKMESLDVDSEAKKLLGLGQKHLVMGDIPAAVNAFQEAASLLGKKYGETANECGEAFFFYGKSLLELARMENGVLGNALEGVHVEEEEGEKTEDESLVENNDNVDEEAREELREQVYDAMGEKEAKKAEGQSLTKPETDKEQESEVEKGGREDMDISEPAEKLQEKVESTSKQLTESSEEAKEAAIPGLNEDEVTSGKTEQESLCTEEGKSISGVYVQNKEFREAVPQEEGEEMISLEKKPKETSEDQTIGAPEKQDTLMKVVEIEAEIDSEVKSVDVGGEEPKDQGAISESELGKAVLMQLSGQDVEVSPVVAAEAGSEVSEKPGQEITVLPNNGPVVGQSSAGDQTPSEPQNSAERLSETKDGASVEEVKAELVPEQEEAMPPVEESEAAGDGVETKVAQRATEKAPEDKFKIAANEETQERDEQMKEGEETEGSEEEDKENDKAEETTNESVLEKKTLQENEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYIQAVEEFQACLSLQEQYLEAHDRLLAETHYQLGLAYGYNSQYDEAVAQFGKSIDVIEKRMAVLLEQMKEAEGSFTEYEKEIEELKELLPEIREKIEDAKESQRSGNVAELALKATLVESSTSGFTPSGAGASVSMIASRKPTDGASSSNCVTDISHLVRKKRKPEEESPRKDDAKKAKPEPEVNGGSGDAVSSGNEVSENMEAEAENQAESQTTAEGTVDSAATVKSTAC
What is the function of this protein?
Required for DNA replication, normal cell cycle progression and cell proliferation.  Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity.  NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
What are the official names of this protein?
Nuclear autoantigenic sperm protein, NASP.
What is the protein family that this protein belongs to?
Belongs to the NASP family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NDK_BURP1
Sequence: MALERTLSIIKPDAVAKNVIGQIYSRFENAGLKIVAARMAHLSRADAEKFYAVHAERPFFKDLVDFMISGPVMIQVLEGEDAILKNRDLMGATDPKKAEKGTIRADFADSIDANAVHGSDAPETARAEVAFFFPEMNVYSR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUM2_ARATH
Sequence: MIPELGRRPMHRGNEDSSFGDDYEKEIGVLLGEQQRRQVEADELERELNLYRSGSAPPTVDGSVSAAGGLFSGGGGAPFLEFGGGNKGNGFGGDDEEFRKDPAYLSYYYANMKLNPRLPPPLMSREDLRVAQRLKGSSNVLGGVGDRRKVNDSQSLFSMPPGFDQRKQHEFEVEKTSASSSEWDANGLIGLPGLGIGGKQKSFADIFQADMGHGHPVTKQPSRPASRNTFDENVDSKNNLSPSASQGIGAPSPYSYAAVLGSSLSRNGTPDPQAIARVPSPCLTPIGSGRVSSNDKRNTSNQSPFNGGLNESSDLVNALSGMNLSGSGGLDERGQAEQDVEKVRNYMFGLQGGHNEVNQHGFPNKSDQAQKATGLLRNSQLRGAQGSTYNDGGGVATQYQHLDSPNYCLNNYGLNPAVASMMANQLGTNNYSPVYENASAASAMGFSGMDSRLHGGGYVSSGQNLSESRNLGRFSNRMMGGGTGLQSHMADPMYHQYADSLDLLNDPSMDVNFMGNSYMNMLELQRAYLGAQKSQYGVPYKSGSPNSHTDYGSPTFGSYPGSPLAHHLLPNSLVSPCSPMRRGEVNMRYPSATRNYAGGVMGSWHMDASLDEGFGSSMLEEFKSNKTRGFELAEIAGHVVEFSSDQYGSRFIQQKLETATSDEKNMVYEEIMPHALALMTDVFGNYVIQKFFEHGLPPQRRELADKLFDNVLPLSLQMYGCRVIQKAIEVVDLDQKIKMVKELDGHVMRCVRDQNGNHVVQKCIECVPEENIEFIISTFFGNVVTLSTHPYGCRVIQRVLEHCHDPDTQSKVMDEIMSTISMLAQDQYGNYVIQHVLEHGKPDERTVIIKELAGKIVQMSQQKFASNVVEKCLTFGGPEEREFLVNEMLGTTDENEPLQAMMKDQFANYVVQKVLETCDDQQRELILGRIKVHLNALKKYTYGKHIVARVEKLVAAGERRMALQSLTQPQMA
What is the function of this protein?
Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of target mRNAs.  Binds the APUM-binding elements (APBEs) in the 3'-UTR mRNA sequence of CLV1, PNH, WUS and FAS2.
What are the official names of this protein?
Pumilio homolog 2, APUM-2, AtPUM2.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURF2_MOUSE
Sequence: MDEPPSDVLAFLRQHPSLRLLPNTRKVRCSLTGHELPCRLPELQEYTRGKKYQRLSSSFSNFDYAAFEPHIVPSTKNRHQLFCKLTLRHINKSPEHVLRHTQGRRYQRALHQYEECQKQGVEYVPACLLHKRKKREDQTNSDELPGQRTGFWEPASSDEEDALSDDSMTDLYPPELFTKRELGKPKNDDTPEDFLTDQQDEKPEHSEEKSFREREEARVGHKRGRKLRKKQLTSLTKKFKSYHHKPKNFSSFKQLGR
What are the official names of this protein?
Surfeit locus protein 2, Surf-2.
What is the protein family that this protein belongs to?
Belongs to the SURF2 family.
Protein: CRPM2_ARATH
Sequence: MGRMDYLAMKTDDVDTVALVNSDMEELKVAAKKLFSDVSKLGGLGFGVSFLKFLASFAAIYLLILDRTNWKTKMLTSLLIPYIFLSLPSVIFNFLSGDVGKWIAFVAVVLRLFFPKHFPDWLEMPGSLILLLVVSPHFLAHHIRGTWIGTVISLFIGCYLLQEHIRASGGFRNSFTQPRGVSNTLGIILLLVYPVWALIVRVM
What are the official names of this protein?
Cold-regulated 413 plasma membrane protein 2, AtCOR413-PM2.
What is the protein family that this protein belongs to?
Belongs to the Cold-regulated 413 protein family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.