PharMolix/UniProtQA huggingface dataset:
Protein: ADRA_PENRW
Sequence: MAVDKLPLLAKFEPVSLVGLVLLSGLFLLLTASRKSDLPLVNGKRPFEFGIAKARQRYLKNAHNLITAGLAKVCNSAGAFRIVTENGTRTILSPNYADDIRSHRDLSLSAALVKEHHVNIAGFDAVKVTVTSDIIQDTVRTKLTQNLLNITEPMSEEATILLKEQWTDNTDWHDVALRPKTLGIVAQLSSRVFLGDKVCRNPDWLRITVNYTIDSLMAAAELRLWPEMLRPLAARFLPKCKKIRKQLEEARDIIQPVIDERRLAQQEAIKQGKPQERYHDAIQWLAENTKDRSFEPAAMQLALSTAAIHTTTDLLGQTVLDLCGRDELIQELREEIISVFKDGSWDKSTMYKLKLMDSVIKESQRVKPMAIAKMARCAEEDVKLSDGTIIPKGEIILVSCSKMWDANVYPDPNTFDPHRFLKMRQPGSDQESFAQLVSPSPEHMGFGFGKHACPGRFFAAAELKVALCHIIMKYDFKVADGCNPQVLKSGMRLAADPFAKIAIRRRQEEVTF
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of andrastins, meroterpenoid compounds that exhibit inhibitory activity against ras farnesyltransferase, suggesting that they could be promising leads for antitumor agents (Ref. 2).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid (DMOA) by the polyketide synthase adrD via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Ref. 2).  DMAO is then converted to farnesyl-DMAO by the prenyltransferase adrG (Ref. 2).  The methyltransferase adrK catalyzes the methylation of the carboxyl group of farnesyl-DMAO to farnesyl-DMAO methyl ester which is further converted to epoxyfarnesyl-DMAO methyl ester by the FAD-dependent monooxygenase adrH (Ref. 2).  The terpene cyclase adrI then catalyzes the carbon skeletal rearrangement to generate the andrastin E, the first compound in the pathway having the andrastin scaffold, with the tetracyclic ring system (Ref. 2).  The post-cyclization tailoring enzymes adrF, adrE, adrJ, and adrA, are involved in the conversion of andrastin E into andrastin A.  The short chain dehydrogenase adrF is responsible for the oxidation of the C-3 a hydroxyl group of andrastin E to yield the corresponding ketone, andrastin D.  The ketoreductase adrE stereoselectively reduces the carbonyl moiety to reverse the stereochemistry of the C-3 position to yield andrastin F.  The acetyltransferase adrJ is the acetyltransferase that attaches the acetyl group to the C-3 hydroxyl group of andrastin F to yield andrastin C.  Finally, the cytochrome P450 monooxygenase adrA catalyzes two sequential oxidation reactions of the C-23 methyl group, to generate the corresponding alcohol andrastin B, and aldehyde andrastin A (Ref. 2).
What are the official names of this protein?
Cytochrome P450 monooxygenase adrA, Andrastin A biosynthesis cluster protein A.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PYRH_STAAM
Sequence: MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAC3A_ARATH
Sequence: MNHGGNTQAVAPMDPNSIENRYGVDGSQTQKYSYQYSTGSESAPWTGHSVENQAVENGNYSNSNYYHPQPTGPATGNVQEIPNTVSFTISSTSGTANVAQDYSGYTPYQTSSDPHNYSNTGYSNYYSGYQQQPSQSYPQPVGAYQNTGAPQPLSSFQNPGSYAGTPSYSGTYYNPADYQTAGGYQSTNYNNQTAGSYPSTNYSNQTPASNQGNYTDYTSNPYQNYTPDAANTHSSTIATTPPVHYQQNYQQWTEYYSQTEVPCAPGTEKLSTPTTSAYSQSFPVPGVTSEMPASNSQPAPSYVQPWRPETDSSHPPSQQPGAAVSTSNDTYWMHQAPSLQAHHPVPPQNNYQSPLETKPLYETPFQGHQRATYPQEMNSQSSFHQAPLGYRQPTQTAPLVDSQRVSKVQIPTNPRIASNLPSGFTKMDKDSTAASAAQAPAYVSVSMPKPKDHTTAMSDPGTFPKSLRGFVERAFARCKDDKEKESCEVALRKIVKKAKEDNTLYTRDWDTEPLSTVTTTNVTNSESSSAQLSSLQNKSPTRRPKSRWEPLVEGKPFVKPASTFSSAVKFGVWNHQNENNKKSSESFQKVDAATGFKPTYSGQNSAKKSFQRPVKRQRFSGGAATAIDDEASSDSDKDLTPYYSSAMALAGSAEEKKRRDSRSKRFEKIQGHSRGNDLTKPKNANVGNLHSRRATALRLSKVFDESGSRAVEDIDWDALTVKGTCQEIEKRYLRLTSAPDPATVRPEDVLEKALIMVQDSQKNYLFKCDQLKSIRQDLTVQRIHNHLTAKVYETHARLALEAGDLPEYNQCLSQLKTLYAEGVEGCSLEFAAYSLLYITLHSNNNRELLSSMSRLSEEDKKDEAVRHALSVRAAVTSGNYVMFFRLYKTAPNMNSCLMDLYVEKMRYKAVNFMSRSCRPTIPVSYIVQVLGFTGAASEGTDEKETDGMEDCLEWLKTHGANIITDSNGDMLLDTKATSTSLFMPEPEDAVAHGDRNLDVNDFFTRT
What is the function of this protein?
Component of the TREX-2 complex (transcription and export complex 2), a muliprotein complex that functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (PubMed:19843313).
What are the official names of this protein?
SAC3 family protein A.
What is the protein family that this protein belongs to?
Belongs to the SAC3 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBA50_SCHPO
Sequence: MENHRSVFSNVIGDIVEKPPKQLVEVKRSVQRHARGFPAVSRTLPKRESKSMSAYKEKMLRKNKESPGLEGKGNLDDQGIDEENRVRLERMNDLEIEGAQEEIRATIRDDLLEMLKKRAFKKKAERELAQRKDRSSQVNTPDLSQRPSDDSFLSNEKLRSSEKLNRNLQSVLSSEAVDSSSGSPSPPMALSQAEIRSRQTKRVMFPDKAEELTKIFSLPTLAPIKGNEEDDASEDAKHSPKKHSPALSDGTTSNDGAPLEFDTTHLPEKQVTLDPNDPSFYEQLHDKYFPNLPVDEKQMQWLHDPSPAENSYHPSVESLHAHEIRFGFKGEIITPSQSQTIPVNEGLHHHGDAPFSAGYTLVELAHLLRSSFPTQRCIAIQTIGRIIYRLNSGEFREVLSPELHTLVEDAHIYELLAAAASDQVKHLTVRSLAIEALWLCSQSQHGSSRSAV
What is the function of this protein?
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation.
What are the official names of this protein?
RNA polymerase II-associated protein rba50.
What is the protein family that this protein belongs to?
Belongs to the RPAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPB_RHOE4
Sequence: MTAAVTENNGAGSASAVAGRVVRVIGPVVDVEFPRGAVPELFNALNAEITLPSVAKTLTLEVAQHLGDNLVRTVSMQPTDGLVRGTAVTDSGKPISVPVGDVVKGHVFNALGDCLDTPGLGRDGEQWGIHRKPPAFDQLEGKTEILETGIKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLHLEMEEMGVLQDTALVFGQMDEPPGTRMRVALSALTMAEYFRDVQGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSLQAIYVPADDYTDPAPATTFAHLDATTELSRPISQMGIYPAVDPLSSTSRILEPGIVGAEHFRVANEVKRILQKYKELQDIIAILGMDELQEEDKVLVGRARRIQKFLGQNFIVAEKFTGEPGSVVPLRDTIEAFDRVCKGEFDHLPEQAFNSCGGLDDVEAAAKKMAGK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y835_YERP3
Sequence: MNLQHHFLIAMPSLQDPQFKRSVIYICEHDEKGAMGLVINKPLEQLTVETILEKLKIKSPSRDPAIRLDNVVLAGGPLAEDRGFILHSPQEGFASSIHISPETMITTSKDVLETLGTSGQPKNLLVALGYASWRQGQLEQELLDNVWLTTEADTHILFNTPIAERWQAAANKLGINIFNIAPQAGHA
What are the official names of this protein?
UPF0301 protein YpsIP31758_0835.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: YNAJ_ECO57
Sequence: MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIPLSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ
What are the official names of this protein?
Uncharacterized protein YnaJ.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LNT_PSEAE
Sequence: MRWISRPGWPGHLLALAAGALTPLALAPFDYWPLAILSIALLYLGLRGLPGKSALWRGWWYGFGAFGAGTSWIYVSIHDYGAASVPLASLLMLGFTAGVAFFFALPAWLWARCLRRDNAPLGDALAFAALWLALELFRSWFLTGFPWLYAGYSQLQGPLAGLVPVGGVWLSSFVIALSAALLVNLPRLFPHGASLLLGLVLLLGPWAAGLYLKGHAWTHSAGEPLRVVAIQGNIAQELKWDPNQVRAQLDLYRDLSLPQQDVDLIVWPETAVPILQDMASGYLGAMGQVADEKNAALITGVPVRERLADGKSRYFNGITVVGEGAGTYLKQKLVPFGEYVPLQDLLRGLIAFFDLPMSDFARGPADQPLLKAKGYQIAPYICYEVVYPEFAAALAAQSQVLLTVSNDTWFGTSIGPLQHLQMAQMRALESGRWMIRATNNGVTGLIDPYGRIVRQIPQFQQGILRGEVIPMQGLTPYLQYRVWPLAGLAGVLLLWALLGRQLRPQERRLFG
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase, Copper homeostasis protein CutE homolog.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CTR1_LUMTE
Sequence: VIGGSDTTIGQYPHQLSLR
What are the official names of this protein?
Chymotrypsin LT_CH 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: GATA_BORBR
Sequence: MTQSALHTEFGGIAALRDALARRQVSAVELAQSGLDAAQAASGLNAFLHIDPELTLAQARAADAALAAGTAGPLAGIPIAHKDAFVTRGWRTTAGSKMLAGYASPFDATVVERLAEAGAVSLGKLNCDEFAMGSGNENSAYGPVRNPWDTRAVPGGSSGGSAAAVAARLVAAATGTDTGGSVRQPAALCGVSGIKPTYGTVSRYGMIAFGSSLDQAGPLAPSSRDLLELLDVMTGFDPRDATSLQACDGQANESGRVRRGHDAAQAGYDAAGSQPLKGLRIGVPQEYFGAGLAPDVAAAVEAALAQFEQLGAVRVPVSLPRTELAIPAYYVIAPAEASSNLARYDGVRYGHRAAQYGDLNEMISRSRAEGFGDEVKRRILIGTYVLSHGYYDAYYLQAQRLRRLIAQDFQRAFADQCDVIMGPVSPTVAKNIGDNRDDPTADWLADVYTLGVSLAGLPAMSVPCGFGGQDGRRPVGLQIIGNYFDEGRLLALADRYQQVTDWHQRAPVSQDA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: SAS6_XENLA
Sequence: MADELFCKVLSIGIKCRECEDRRANVRLTVESRSSSNPVHKKELVVRLSDDTDPFFLYNLTLGEEDFQSLKNQQGLLVEFSAFPQRFIDLLEQCILEQEKPVPRFLLQLAMSSNALDCMPASLNIIETNPFKHLIHLSLKLLAGSDSDVKKYLATCIKNLKLENCTLKEKLHKSEEDLSKRLGVTQQALAEKCKELDKLRNEWASQTSLLTSKHTQEIGAEREKALQIQTQYQLQYEQQKKELETTSSRTVHHLESRVSELEAVNKDLTERKYKSESCIRELKGKLSGIEEEYHRAKQEVTSLRRENATLDSECHEKEKLINQLKTKTAVLEQEVKDKEHVIIRSVDACESAQEHKKKLEDSLEQKQMQTGKLETTVKSLSEELIKANEIIKKLQTDMKKLMEKIKLKNAVTMQQEKLLGEKEQTLQKEKLELTNVKHLLKIKEEEMLKLKEQLDSTTEKLEESKQQLKTNENVIAWLNKQLNENKIATLQGPHGLHEMPSSLKTVGSASNVGVMQSTQPQFTIGNDPYMVSPITQPIGSAFVSNFYPKNFAPGMSAPSSISLGTRLNPQAAFKANVRFNQSPTALCSPAVEPRPAPSTSTPILPSTSCDPVGLDMKYLKKNGSVPVKGQRNGSSAGTVPVRPALPKSGSSPILSAYFPGQQSRLPAS
What is the function of this protein?
Central scaffolding component of the centrioles ensuring their 9-fold symmetry.  Required for centrosome biogenesis and duplication: required both for mother-centriole-dependent centriole duplication and deuterosome-dependent centriole amplification in multiciliated cells (By similarity).
What are the official names of this protein?
Spindle assembly abnormal protein 6 homolog.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Component of the centrosome (By similarity). Component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells that can generate more than 100 centrioles.
Protein: SURE_CHRVO
Sequence: MKFLLSNDDGYFAPGLAMLAQTLQRYGEVVVVAPERDRSGASNSLTLDRPLTVRKAANGFHYVNGTPTDCVHLAVTGFLDFRPNMIFTGINHGPNMGDDTLYSGTVAAATEGFMLGIPSVAVSLAGHSGKHFASAGKVVEQLVERCLEEPFQQPVLLNVNVPDAPPEEVGALQVTRLGRRHAAQPVIKSQNPRGETIYWVGPVGAVQDAGAGTDFGCVASKQVSVTPLMLDLTAYGQLDRISTWLHR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14E_THEKO
Sequence: MPAIEVGRIAVVIAGRRAGQKVVVADIIDKNFVLVTGAGLNKVKRRRMNVKHLEPLPERVNIQRGASDEEIKAALEGAGISLE
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: GLGA_YERPY
Sequence: MRVLHVCSELFPLLKTGGLADVIGALPAAQLAEGADVRIILPAFPDLRRGIPETVLVREIDTFAGRVALRYGHYRGIGIYLIDAPALYDRAGSPYHDASLYAYSDNYLRFALLGWMACELACGLDGYWRPEVVHAHDWHAGLTCAYLAARGRPARSVFTVHNLAYQGLFSADHLSELHLPAEFFQIYGLEFYGQISYLKAGLFFADHVTTVSPTYAKEITQPAFGYGMEGLLQALARQGRLTGILNGVDSDIWDPQSDTLLPTRYDAENLQAKAINKTHLQTAMGLQLAENKPIFAVVSRLTVQKGLDLVLEALPELLALGGQLVVLGSGDATLQEAFLAAAAEHSGQVGVQIGYHEAFSHRIIAGSDVILVPSRFEPCGLTQLYGLKYGTLPLVRHTGGLADTVVDCALENLADGSASGFVFNECEAQALVKAIRRAFVLWSRPKHWRHVQRHAMRLDFGWQLAAVDYLSLYRRL
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: GCH1_STRPG
Sequence: MKRERLMSINKEKAEAAIYQFLEAIGENPNREGLLDTPKRVAKMYAEMFLGLGKDPKEEFTAVFKEHHEDVVIVKDISFYSICEHHLVPFYGKAHIAYLPSDGRVTGLSKLARAVEVASKRPQLQERLTSQIADALVEALNPKGTLVMVEAEHMCMTMRGIKKPGSKTITTTARGLYKESRAERQEVISLMTKD
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: TBL1X_HUMAN
Sequence: MTELAGASSSCCHRPAGRGAMQSVLHHFQRLRGREGGSHFINTSSPRGEAKMSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDGRPIESLSLIDAVMPDVVQTRQQAFREKLAQQQASAAAAAAAATAAATAATTTSAGVSHQNPSKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
What is the function of this protein?
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units (PubMed:14980219).  Plays an essential role in transcription activation mediated by nuclear receptors.  Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange (PubMed:21240272).
What are the official names of this protein?
F-box-like/WD repeat-containing protein TBL1X, SMAP55, Transducin beta-like protein 1X, Transducin-beta-like protein 1, X-linked.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EBI family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalized with MECP2 to the heterochromatin foci.
Protein: SNP47_MOUSE
Sequence: MSSDMRVHSWSCSYYLDLEKQWVSGKLTLTPHSLKFIVEKTEEVLVGLPLSSIIEIRKESSLFIFGAITVLEKGQTKHWFSSLQPSRNVVFNVIEHFWRELLLSQPGTAANIPSHVTRGQELIGLMANSQKRMEDTAKDLQQQSEQLDSVLKGLEKMESDLDVADRLLTELETPSWWPFGSKFWKMPAEENLKEGVSSTCEPFGKEGVVITVPAIISERAESHSKLGKLTVLVSALEIYDSCSLLLHRFEKEDVDDIKVHSPYEVSIRQRFIGKPDVAYQLISAKMPEVIPILEVQFSSKIELLEDALVLRNKVFASSAERHAASRPKGCTPHRELPTGGQEGEQLQLQKNLPLFSEGEAQELTQILSKMKGLALDTEAELERQDAALDGITVAVDRATLNVDKQNRRMRKLM
What is the function of this protein?
May play a role in intracellular membrane fusion.
What are the official names of this protein?
Synaptosomal-associated protein 47, SNAP-47, Synaptosomal-associated 47 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the SVAP1 family.
What are the subcellular locations of this protein?
Endomembrane system. Cytoplasm, perinuclear region. Note=Appears to be exclusively membrane- bound. In primary neurons, widely distributed in both cell bodies and neuronal processes.
Protein: CGLH_STEMA
Sequence: MRPWVPVTGASPHAAVGPAWTTGRRCVGVVTTWWWSVSYVERQVQIIDSLYRAMDASAENGYTDAACRFRYLPEEDGSLGIDSSFFYTIGGVSVSALLNDYGDKGCADLVYDLHDVMYKDIRFGESIRSRMCPRGVNPVPSAPTAPPAGLAAFPSANRRTERCLVWIACVHRLSAVGEAGSLNEPEAARLANDPAEHSNRHVDALGRQQLVCAHVVAGVASDGFGVRAGEERTGARGRHSGSIKPLDNLVVETPIEAARSRHRCAGRPCPRRHRRPCNASKSHRPMRMQQRDRGWTVWQKDFSMLTPLSAGFQHRVLAQQLVARRGRMQPSVVQIGVGRIRADVAGRVAGQDALGRIGRILPNAVARLSIAVRFLRAQSINHSIQSKRDRRSWNGCSKGQRRRGFISIDKKPGPKNKLALMFIREPDRFISIDRNPARRTSWL
What is the function of this protein?
Cell wall protein that resembles the beta subunit of human chorionic gonadotropin.  Stimulates growth and change in morphology.
What are the official names of this protein?
Chorionicgonadotropic hormone-like protein, CG-like protein.
What is the protein family that this protein belongs to?
To mammalian CGHB.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: GPDA_CAUSK
Sequence: MTFQHAGVIGAGAWGTALAQVCARAGLTVTLQAREPEVTASIAAERENTLFLAGVKLEDAITASTDMAALAGCDLILAVPPAQHLRSALTALKPHLKPGAPVVLCSKGVEQGSLKLMSDVAAEVLPGAPIAVLSGPSFAGEVARGLPTAVTLACEDEALGRRIGQALAIPTFRPYWADDVIGAEAGGAVKNVLAIACGIVEGKGLGRSAHAALITRGFAELTRLAVALGGKSETVAGLCGLGDLVLTCSSPQSRNMSVGLALGGGQTLEQALAGKVSVAEGVASAPAVRALAHSLNVETPICEAVAAILAGEVDVDSAILGLLSRPLKAEV
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_BRUMB
Sequence: MSEQKSSNQMWGGRFASGPDAIMEEINASIGFDRKLYAQDIQGSLAHAAMLAKTGIIAAEDHKQIENGLKTIRKEIEEGKFTFSRKLEDIHMNIEARLAELIGPAAGRLHTARSRNDQVAVDFRLWVKQELEKTAAALKNLIEAFLERAEEHAATVMPGFTHLQTAQPVTFGHHCMAYVEMFGRDLSRVRDAIERIDESPLGAAALAGTGFPIDRHMTAKALGFREPTRNSLDSVSDRDYALEFLSLAAICAGHLSRLAEEIVIWSTPQFNFVRLSDAFSTGSSIMPQKKNPDAAELVRAKTGRINGSLVALLTIMKGLPLAYSKDMQEDKEQVFDAAENLELAIAAMAGMVRDLTVNVAAMKKAAGSGYSTATDLADWLVRTLGLPFREAHHVTGRAVALAESRKVDLAKLSLEELQSINPAITAEVFGYLTVEKSVKSRQSFGGTAPQEVRRQIRYWKKRIAKA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIC_PSEPK
Sequence: MSYESPQAAAVAWLPYSQLATDIDQPTLDWLFDEGSLTRRLTRLSIDHFSVTPLFEGWQPLRDDECQALGIAAGAEGWVREVYLRGHGQPWVFARSVASRSALERGGLDLETLGSRSLGELLFCDQAFIRHPLEVCTYPQAWLPSEAAHAALWGRRSRFERNGLDLLVAEVFLPALWQAAKEENR
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_BURL3
Sequence: MPKMKTKKSAAKRFVVRPGGTVKRGQAFKRHILTKKTTKNKRHLRGATAVHDSDLNSVRAMLPFA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PRGR_ATEPA
Sequence: MTELKAKGXRAPHVAGSPSSPKVXSPLPCRQAAXPFPGSQTSDTLPEVSALPISLDGLLFPRICQGQDPPDEKTQDQQSLSDVEGAYSRVEATRGAGGSSSRPPEKDSGLLDSVLDTLWAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPGTSATQRVLSRLMSRSGGKAGDSSGMAAAHKVLPRGLSPSRQLLLPTTGSPHWSGAPVKPSPQSAALEVEEEDGSESEDSAGPLLKGKPRALGGAAAGGGAAAVPPGAXAGGIALVPKEDSCFSAPRVALVEQDAPMAPGRSPLATTVTDFIHVPILPLSHALLAARTRQLLEDESYDGGAGAASAFAPPRSSPSASSTPVPGGDFPDCAYAPDAEPKDDAYPVYGDFQPPALKIKEEEEGAEASARSPRSYLVAGASPAAFPDFPLGPPPPLPPRAPPSRPGEAAVTAAPASASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAPGAGGCLLPRDSLPSTSASAAATAAGAAPALYPALGLNGLPQLGYQAAVLKEGLPQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVALPQPVGIPNENQALSQRFTFSPNQDIQLIPPLINLLLSIEPDVIYAGHDHTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVPSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: CLPP_CALS8
Sequence: MSALVPIVIEQTNRGERAYDIYSRLLKDRIVILSGEITDDIASLIVAQLLFLEAEDPDKDIYLYINSPGGSVTAGFAIYDTIQYIKPDVSTICVGMAASMGAFLLAAGAKGKRFALPNSEIMIHQPIGGVRGQATDIKIHAEWILKIKQRINRILAERTGQPIEVIERDTERDFFMTAEEALKYGIIDKVIERRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H4_SEPOF
Sequence: MSGRGKGGKGLGKGGAKR
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.