PharMolix/UniProtQA huggingface dataset:
Protein: LPXD_PORGI
Sequence: MEFTAQQIADYLHGSVEGNPKVRLHDFAKIEEGRSGCLSFLANAKYEHYLYQTQSDAVLVNQDFEPRESVKTTLIRVPNAYTALAQLMQLVDSMKPQRKGVDSTAFVHPSVILPDDCYVGAFAYVSEGASLGTGCSLYPHVYVGSGVSVGEGTILYPHVTVYDGCSIGSRCVIHSGAVIGADGFGFAPNAEGYSKIPQLGNVIIEDDVEIGANTCIDRAVMDSTIIHRGVKLDNLVQIAHNCSVGSHTVFAAQVGMAGSSHVGEWCQFGGQVGLSGHIKVGDRVSLGGQTGLLSNVKSGSTLLGSPGMPLRDMLRASVIFPKLPDMSLRIEQLEKEISELKEICKNNKH
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: AAS_PECCP
Sequence: MIHTLLRWVFQRLYRIRIEGDSSQFQQSKLLITPNHVSFLDGILLALFLPIKPVFAVYSSISDRWFMRWLKPYIDFVPLDPTKPLAIKGLIKVIERGQPVVVFPEGRISVTGSLMKIYSGAAFVAAKSGATIIPVRIDGAEFTPFGRLAGVFKRRCFPQITITYLPPTTLPMPEADSARTRRALAGEHLHQIMMKARMETRPQHTLYEAFLAARTRYGRRSPSIADISFNEDSYQGLLKKSLGVSRILQRFTRADEHVGMLLPNATITAASILGASLRNRIPAMLNYTAGAKGLQSAMKAAGIKTIVTSRQFLEKGKLTDLPKQVSEANWVYLEDLKDTVTLADKLWILFHLLFPARAMLPQKPDDAAIVLFTSGSEGNPKGVVHSHDSLLANVEQIRTVADFTPRDRFMSALPLFHAFGLTVGLLTPLMTGARIFLYPSPLHYRIVPELVYDQNCTVLFGTSTFLGNYARFAHPYDFARLRYVVAGAEKLSETTRQVWQDKFGIRILEGYGVTECAPVVAINVPMATKIHSVGLLLPEIESRLITVPGITRGGRLQLRGPNIMKGYLRVENPGVLEAPAAENAEGELQQGWYDTGDIVELDEKGFCTIIGRVKRFAKLAGEMVSLESVEQLAVKVSPEAQHAASAKSDSSKGEALVLFTTDSQITRDVLLAQARSSGVPELAVPRDIRYVKALPLLGSGKPDFVTLRHMAEEPVTNASEQSA
What is the function of this protein?
Plays a role in lysophospholipid acylation.  Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium.  Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1.
What are the official names of this protein?
Bifunctional protein Aas.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL37A_METM7
Sequence: MVEFSHTKKIGSAGRFGSRYGRKIRVRLRDVEIKQKKEYKCPVCAFPKLKRVGTSIWVCDKCGAKIAGGAYTPETGAGKVVTKAIRRVIESKSREI
What are the official names of this protein?
50S ribosomal protein L37Ae, Ribosomal protein L43e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: SSUD_ECOBW
Sequence: MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGYTGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGRALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLQRETVDFNGKHIHVRGAKLLFPAIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAHGRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAALHNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPHLEEAYRVGELLFPLLDVAIPEIPQPQPLNPQGEAVANDFIPRKVAQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: ILVD_DECAR
Sequence: MPQYRSHTSTHGRNMAGARSLWRATGMKDGDFGKPIIAVVNSFTQFVPGHVHLKDMGQLVAREIEAAGGVAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPVIFVSGGPMEAGKVKIQGQVIHLDLIDAMVKAADHSVSQAELDDVERSACPTCGSCSGMFTANSMNCLTEAFGLSLPGNGTVVATHADRKQLFLRAGRQIVELCKRYYEQDDASVLPRAIATKAAFENAMTLDVAMGGSTNTVLHILATAQEAGVDFTMADIDRISRSVPCLCKVAPMTDKYHIEDVHRAGGIMGILGELDRAGLINRDVPNVYAKNLGEAIDRWDVVRQHDVKVHEFFKAAPGGVPTQVAFSQDRRFNELDIDRTHGCIRNKANAYSQEGGLAVLYGNIALDGCIVKTAGVDESIWKFTGKARVFESQDAAVEAILGEKIVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSMGLGKECALLTDGRFSGGTSGLSIGHASPEAADGGAIGLVEEGDTIEIDIPNRRIHLAVTDGELAQRRAAMEAKGEAAWQPVSRERVISPALQAYALMATSADKGAVRDVKQIQRRK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: NEPI_SALEP
Sequence: MNENIAEKFRADGVARPNWSAVFAVAFCVACLITVEFLPVSLLTPMAQDLGISEGIAGQSVTVTAFVAMFSSLFITQIIQATDRRYIVILFAVLLTASCLMVSFANSFTLLLLGRACLGLALGGFWAMSASLTMRLVPARTVPKALSVIFGAVSIALVIAAPLGSFLGGIIGWRNVFNAAAVMGVLCVIWVVKSLPSLPGEPSHQKQNMFSLLQRPGVMAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFDVDGLTLVLLSFGIASFVGTSFSSYVLKRSVKLALAGAPLLLALSALTLIVWGSDKTVAAVIAIIWGLAFALVPVGWSTWITRSLADQAEKAGSIQVAVIQLANTCGAAVGGYALDNFGLLSPLALSGCLMLLTALVVAAKVRITPMS
What is the function of this protein?
Involved in the efflux of purine ribonucleosides, such as inosine and guanosine.
What are the official names of this protein?
Purine ribonucleoside efflux pump NepI.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. NepI (TC 2.A.1.2.26) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NCPP_PYRIL
Sequence: MIVAVASRNPNKLRAVQAAYKLFGMRAQVVPVEKPVSLPPQPIGVETVVAGAIERARAALSVVQNAEHGVGIEAGVLQAGGRYLDVTVAAIADRNGVVTIGFGPAFQVPDIFLNDVLRGVELGVLAERYFGRVAIGYKEGIIGVLTKGVVSRFDLNMAAVVMALVPRLSTNAPLYRF
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Probable inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: ILVD_STRR6
Sequence: MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVISTWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDIIADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKDIDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLPGSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNATLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLLANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDGAVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEMLSLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQDTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGKK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: METN1_RHOPA
Sequence: MNEPIMNAPWQPPAGELPAFVSSQPTIGILIDRVRKVYPARKSSAEVVALDDISLTVPKGSILGVIGRSGAGKSTLIRLINGLDKPSSGRVIVNGVEITALSERDLRTARRSIGMVFQHFNLLSSRTAFGNVALPLEIAGTPKAEIEKRVLPLLDMVGLADKRDRYPAELSGGQKQRVGIARALATEPSVLLSDEATSALDPETTDQILELLKQINRDLHLTILFITHEMAVVKALADRVAVIEGGRIVEDGATFDVFATPRHEVTRRFVSSVTGSGAPDWLLEKLQPQQPPGGQAVLRITFKGSDANQPLLSRVSRDLGVNLNILSGQVEMIAGHPFGTLIVSLDAAPEVLRQVIAQLSAGNNLVEQLGYVA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RAB5B_PLAF7
Sequence: MGCSSSTERLTSTKNINIVTSPAQQQKKNAQDTKVKIVLLGDSGVGKSSIALYLCHGRFSEKHQVTIGAAFLHHNIELKNGATMKLHIWDTGGQERFRSMAPLYYRDAYGAVVVYDSNNVESFDSLKYWINEIKSNGPRNCCIMVVANKKDLPQKLNSEMVMKFCEQENVSFIECSAKTGENITTLFEKLASRIYSRFKEVLYYNNP
What is the function of this protein?
Small GTPase which regulates vesicle trafficking between organelles (Probable).  May be involved in the trafficking of the N-myristoylated AK2 from the endoplasmic reticulum to the parasitophorous vacuole membrane (PubMed:27316546).
What are the official names of this protein?
Ras-related protein Rab-5B, PfRab5B.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: RL27_STRP1
Sequence: MNLANLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPVAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: IDRA_DENS1
Sequence: MSENIKQGGAGTFMQAPQDSVPLPPKDAEVMTTACDYCTVACGYKVYRWPVGKEGGMKAKDNAFNADFPHQQIFGAWASPAQHNIVNHNGRSHHVLVLPDRDTTVVNPGGNHSIRGGTLAQKCYNPSNRTSERLLYPMIRVRGTLMPVSWDLATEVMADISQYILAKYGEHAWAMKTYSYQYFENTYAITKLGMTSIGTPAFAWHDKASATNDATGLDDAGVNSFASSDQDWADCEVAFLSGVDPYETKTTLFTQWMMPGDKKFIFVTPHRTMGVAWAESTGRGMWLPIIPGTDTVLHLALARIIVENGWQDQAFIDKWVANKWEVDSGYGRGTRNTGWQWRTTWGKWQSDWKDYSAWILKQKEGELETAAKITGLRAEDIRKAAEWIAKPKADGTRVKASFMLEKGNYWTNNYMNSASLASLGLICGSGNRPGQMISRGGGHQRGGMSAGGGSGWLSPEKYPGRRKKSFNLDRWMMNGNVRFAWVIGTTWTAAMMASQALQDKMFSLTRGNPHQISSLDRKAIFETLKQRVDSGGTVIANSDIYPCVPVGTEYADIVLPAATWGEDNFTRCNSERRLRLYSKFYDAPGEAKPDWWIIAKFAQKMGYDKDGSYQWKNSNDVFEEAARFGRNGVLNYHPLVVKAKEKGVKGHELLRTYGTDGIQTPIRMKDGELVGTQRLHDPANDWDEVEGQEVKRKWLYAFGTHSGKAILLKTPWDYPGWSQFYKAALPRKEKGEVWVTNGRVNETWQSGFDDLRKPYLSQRWPYPMLIMHPDEAKPRGIESGDFVQVYNDTVYIQMGEPQGVKEDDLYFDTLMKNGHIKTTDGQFVAVAIVSEEMRPGVVMANFNYPQAPANSVVHAVPDPMTNNYRYKLGRGVLTKVGESPYKHSFTSMTLKPRDIV
What is the function of this protein?
Involved in iodate respiration (PubMed:34215855).  May accept electrons from cytochrome c551, and catalyze the reduction of iodate (IO(3)(-)) to produce the chemically unstable intermediate hypoiodous acid (HIO).  This intermediate then undergoes abiotic disproportionation to yield two molecules of iodide (I(-)) and one molecule of iodate.  The resultant iodate subsequently cycles back into the reductive pathway (PubMed:34215855).  The initial reduction of iodate may inadvertently produce low levels of incidental toxic H(2)O(2), which is detoxified by IdrP1 and IdrP2 (PubMed:34215855).
What are the official names of this protein?
Iodate reductase subunit IdrA.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
What are the subcellular locations of this protein?
Periplasm. Note=May be co-transported with IdrB into the periplasm.
Protein: ATPD_SYNWW
Sequence: MLNKSVARRYAEAFFSIARETGKVDELQQELEKLVSIIETTENLPEYFAHLLIPAKAKKEVANKLFGGQVSQLTLNFLNMIIDKRRETYIGLISEEYRDMADELRNITKAELTAAAPVSEADMKNLEQNLSAKTGKTVQLSLKVDPGLIGGLKIRIGDQIVDATVAKKLEMLKEQLKQAKIS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CYH2_VIOHE
Sequence: SAIACGESCVYIPCFIPGCSCRNRVCYLN
What is the function of this protein?
Probably participates in a plant defense mechanism.
What are the official names of this protein?
Cycloviolacin-H2.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Bracelet subfamily.
Protein: RL23A_DICDI
Sequence: MAGKKVKSNTPKQDLSVSKSKLTSIKAPAAAIKAKAAASAVKKGVSNKSTRKVRTSVIFRRPVTLNNPKKPAYPRRSVNKITKMDQFRILKAPLTTESATQKIEGSNTITFMVDMFANKSQVADAVAKMYDVKVKRVNTLITPRGEKKAFVTLSPEFEAADVANKIGLI
What is the function of this protein?
This protein binds to a specific region on the 26S rRNA.
What are the official names of this protein?
60S ribosomal protein L23a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RPIA_BURCJ
Sequence: MTQDELKRLVGQAAADYVIQNVPEGAVIGVGTGSTANCFIDALAAVKSRYRGAVSSSVATTERLKSHGIKVFDLNEIDALQVYVDGADEIDAGGAMIKGGGGALTREKIVASVADTFVCIADGSKRVPVLGAFPLPIEVVPMARTAIGRRVTALGGVPVLRVTKDGAPYITDNGNEIIDVKGLQIADPRGFEARVNAWPGVVTVGLFAERGANLCLLGTENGVETIVYPAA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: HSLV_ZYMMO
Sequence: MSEDKIGWHGTTILSVRRNGRVVIAGDGQVSMGNTVMKPNARKVRRLGDGSVIGGFAGATADAFTLFERLEAKLERHNGQLLRAAVELAKDWRTDKYLRNLEALMIVADDQVTLVLTGNGDVLEPVGGIAAIGSGGNFALSAARALVDYEEDAEVIARKALAVAADICVFTNDQVTIETLESRV
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_CALFL
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIVYQAVKKIQQKTETNPLSVLRQAICRVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SIK2_HUMAN
Sequence: MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRITKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLTIAQIKEHKWMLIEVPVQRPVLYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTIESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTIAEQTVAKAQTVGLPVTMHSPNMRLLRSALLPQASNVEAFSFPASGCQAEAAFMEEECVDTPKVNGCLLDPVPPVLVRKGCQSLPSNMMETSIDEGLETEGEAEEDPAHAFEAFQSTRSGQRRHTLSEVTNQLVVMPGAGKIFSMNDSPSLDSVDSEYDMGSVQRDLNFLEDNPSLKDIMLANQPSPRMTSPFISLRPTNPAMQALSSQKREVHNRSPVSFREGRRASDTSLTQGIVAFRQHLQNLARTKGILELNKVQLLYEQIGPEADPNLAPAAPQLQDLASSCPQEEVSQQQESVSTLPASVHPQLSPRQSLETQYLQHRLQKPSLLSKAQNTCQLYCKEPPRSLEQQLQEHRLQQKRLFLQKQSQLQAYFNQMQIAESSYPQPSQQLPLPRQETPPPSQQAPPFSLTQPLSPVLEPSSEQMQYSPFLSQYQEMQLQPLPSTSGPRAAPPLPTQLQQQQPPPPPPPPPPRQPGAAPAPLQFSYQTCELPSAASPAPDYPTPCQYPVDGAQQSDLTGPDCPRSPGLQEAPSSYDPLALSELPGLFDCEMLDAVDPQHNGYVLVN
What is the function of this protein?
Serine/threonine-protein kinase that plays a role in many biological processes such as fatty acid oxidation, autophagy, immune response or glucose metabolism (PubMed:23322770, PubMed:26983400).  Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction.  Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators (PubMed:15454081).  Phosphorylates EP300 and thus inhibits its histone acetyltransferase activity (PubMed:21084751, PubMed:26983400).  In turn, regulates the DNA-binding ability of several transcription factors such as PPARA or MLXIPL (PubMed:21084751, PubMed:26983400).  Also plays a role in thymic T-cell development (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase SIK2, Qin-induced kinase, Salt-inducible kinase 2, SIK-2, Serine/threonine-protein kinase SNF1-like kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: TRPB_STRCO
Sequence: MPSNFFIPDPEGQVPSAEGYFGAFGGKFIPEALVAAVDEVAVEYDKAKSDPEFARELDDLLVHYTGRPSALTEVPRFAAEAGGARIFLKREDLNHTGSHKINNVLGQALLTKRMGKTRVIAETGAGQHGVATATACALFGLDCTIYMGEIDTRRQALNVARMRMLGAEVIAVKSGSRTLKDAINEAFRDWVANVDRTHYLFGTVAGPHPFPAMVRDFHRVIGVEARRQLLEQAGRLPDAAIACVGGGSNAIGLFHAFIPDADVRLIGCEPAGHGVETGEHAATLTAGEPGILHGSRSYVLQDDEGQITEPYSISAGLDYPGIGPEHAYLKDSGRGEYRAVTDDAAMQALRLLSRTEGIIPAIESAHALAGALEVGRELGRDGLLVVNLSGRGDKDMDTAARYFGLYDTDAEVAADGTGAAEIEGDAK
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: ENO_BURCJ
Sequence: MSAIVDIIGREILDSRGNPTVECDVLLESGTMGRAAVPSGASTGSREAIELRDGEAGRYNGKGVLKAVEHINTEISEAIMGLDASEQAFLDKTLLELDGTDNKSRLGANAMLAVSMAVAKAAAEEAGLPLYRYFGGSGAMQLPVPMMNIVNGGAHANNSLDIQEFMIVPVSQPTFREALRCGAEVFHALKKILSDRGMSTAVGDEGGFAPNFGSNDECLSTILQAIEKAGYRAGEDVLLALDCAASEFYHDGKYQLAGEGLQLSSAEFTDYLATLADKFPIVSIEDGMHESDWDGWKLLTDRLGKKVQLVGDDLFVTNTRILKEGIEKGIANSILIKINQIGTLTETFAAIEMAKRAGYTAVISHRSGETEDSTIADIAVGLNAGQIKTGSLSRSDRISKYNQLLRIEEDLGDIASYPGKSAFYNLR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: KDPA_ERWT9
Sequence: MMASASLLIGSYLLLLMLLARPLGKGLAHLVADRPLHGFATAERGLWRVSGVENQGMRWQRYLLAILLFNAAGLLLLLLILMNQASLPLNPQQMPNLSWDLALNTAVSFITNTDWQAYAGESTLSYFSQMAGLTVQNFLSAATGIAVAFALMRGFVNREQGELGNAWRDITRITLYVLLPLSLLMALFLVSQGTLQNLHGYLDLTTLEGAKQTLPMGPVASQEAIKMLGTNGGGFFNANSAHPFENPTALSNFVQMLAIFLIPAALCFAFGDVVRDRRQGHALLWSMSLMFVAAVVVVMWAEVKGNPHFLTLGADSAANMEGKETRFGILNSSLFAVITTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVFIAGLMIGRSPEYLGKKIDVWEMKMTALAILVTPVLVLLGAALAMMTDAGRSAMLNPGTHGFSEVLYALSSAANNNGSAFAGLNANTPFWNMLLAFCMLVGRFGIIVPVLAIAGSLAMKKVQPAGNGTLPTHGTLFIALLIGTVMLVGALTFIPALALGPVAEHLHMSGH
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ACP1_PSEAE
Sequence: MSTIEERVKKIVAEQLGVKEEEVTNSASFVEDLGADSLDTVELVMALEEEFETEIPDEKAEKITTVQEAIDYIVAHQQ
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein 1, ACP 1.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRS2_MOUSE
Sequence: MASAPLPGPPASAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDEASAAGGSPPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRSGEGGSGTTGGSCSASLPGVLGGSAGAAGCDDNYGLVTPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRVRTASEGDGGAAGGAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSAGCGGRPSKVTLAPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGSHPHLPHPLHHPQGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPARDGSGGELYGYMSMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRQVPQPSSASLDEYTLMRATFSGSSGRLCPSFPASSPKVAYNPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAALRSGGPNSCKSDDYMPMSPTSVSAPKQILQPRLAAALPPSGAAVPAPPSGVGRTFPVNGGGYKASSPAESSPEDSGYMRMWCGSKLSMENPDPKLLPNGDYLNMSPSEAGTAGTPPDFSAALRGGSEGLKGIPGHCYSSLPRSYKAPCSCSGDNDQYVLMSSPVGRILEEERLEPQATPGAGTFGAAGGSHTQPHHSAVPSSMRPSAIGGRPEGFLGQRCRAVRPTRLSLEGLQTLPSMQEYPLPTEPKSPGEYINIDFGEAGTRLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPSTRSGDTVGSMDGLLSPEASSPYPPLPPRPSTSPSSLQQPLPPAPGDLYRLPPASAATSQGPTAGSSMSSEPGDNGDYTEMAFGVAATPPQPIVAPPKPEGARVASPTSGLKRLSLMDQVSGVEAFLQVSQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGSSTLGGGDEPPTSPGQAQPLVAVPPVPQARPWNPGQPGALIGCPGGSSSPMRRETSVGFQNGLNYIAIDVRGEQGSLAQSQPQPGDKNSWSRTRSLGGLLGTVGGSGASGVCGGPGTGALPSASTYASIDFLSHHLKEATVVKE
What is the function of this protein?
May mediate the control of various cellular processes by insulin.
What are the official names of this protein?
Insulin receptor substrate 2, IRS-2, 4PS.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y324_STRS7
Sequence: MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAIREMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK
What are the official names of this protein?
UPF0154 protein SZO_03240.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.