PharMolix/UniProtQA huggingface dataset:
Protein: VA0E2_MOUSE
Sequence: MTAHSFALPVIIFTTFWGLIGIAGPWFVPKGPNRGVIITMLVATAVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE
What is the function of this protein?
Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit e 2, V-ATPase subunit e 2, Vacuolar proton pump subunit e 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase e1/e2 subunit family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein.
Protein: TPS1_MELLI
Sequence: MTLSIYDDIFKQFPTIDEWSEPNEKIILEPFTYLGIITAKELPSMLIKAFNYWYQVPPPVLDLILKVVGPFHAATLLIDDIQDDSELRGGIPVAHKVYGVAQTINSANYVYFEAYQNISKLTPYLKSPETTDLWSMFNDEILALHRGQGLELYWRDTFTCPTEEEYLRMVHNKTGGMFRVAIKLMKALSPVQSLPDYFPLVNIIGILVQIRDDLLNLSPAFTKHKGYCEDLSEGKFGFPLIHSIKADSSNTLLMDILKLRPKDVPTKRKALKYMNDQTKSLDYTFDVICKLEKTAKDELKKLGGNPELSSIFELIHLSSTPDIEEKYKS
What is the function of this protein?
Terpene synthase that shows monoterpene synthase activity and produces linalool, using geranyl diphosphate (GPP) as substrate (PubMed:32913319).  Shows also sesquiterpene synthase activity as it is able to convert farnesyl diphosphate (FPP) into (E)-nerolidol (PubMed:32913319).
What are the official names of this protein?
IDS-like terpene synthase 1, ILTPS1.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: RS18_ACIC5
Sequence: MAEETNQQAPESGASSSQPTSRPSGPRGGSGGRKFFRRKKVCKFCTEKIDAIPYRDVRLLQQFVAERGKIVPRRLTGVCTTHQRRLTRAIKQARNIALLPFAARY
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: LST2_DROMO
Sequence: MFVFIYCLQADDKSLLARFYHADRSLTAVASELDSFDGRAEPDRCTRLVSRLRQNQDKVLAITNLIMEELLGDERDPRAFRAKFPEEVLQDNLAGQLWFGAECLAAGSSILNRESESKEMRPLAQAVTKSLGNVRVLLRDQCLRNNVPNSKTLHLDFNDSTTEQLYESLKIFDHLFAEFELSYVSAMVPVKSRHEYEMQQWIGVLFSETLQRALKIGLLEQEMVDAFDPGLMFSIPRLAIVAGLVVFTKGPLNMDMPGDELSEMFRPFRTILIKIRDLLRNLSKQELHQLEKLLCTNEEINTNVPLGSSSIEAPSPEHNNTSSSTSNNNNNNNNNSSSSSSSSSGSGSNTAKTSTSSTHKAVERLVDHRNNNSSTVAGATQPSTARSPSMLSLSAGSTPTASPAPSPTPSHSIASTSSAATTSTNPPANWSDYDEDDEDLEEEVGMLDSDEDDLNDDSDDDIEVDEYIEAQLKAIVAAADCASGYLIPNTNLGNLFQAQQLPLTDNFVASEDDEFGSNAATERQQQQQHMDELQPGDQQQQQQQLQDEPSTSAAMLAAQRTLQRLHLPSSSSENEQAPSSNQQTTIKTPNGNQSMPNSSSSSSNHNNNRHRHSHSHSHSSHHHHHHHRHHHHTHPHHQQQQEQRLQAADHHHHHHHHHQSHPHRINRSARKRCSQEHWESTANAEQPAPEQTPGSADTSNASSFSDEVSLAMRSTTARLKFKSTENLLHRLFVCIAGVADQLQTNFASDLRQILRSVFLINMSSSQDEDIDIPEKTKESELFEFRASENDVIQESAGSNQSIYSAEEVNPELDNVFNNTNAAVRHSAGAAMQRNNTIDLASGNNNGNSNAAARNHVARSRSLGDQEAAGSGTRQDEQRQQQQQQQQQLQQQLQMQRQRNNSVGSNSPSSASSSSSSSEHNSPISTRSGSRRRLHSNSSIGTTSTITPSTAAATATTMSPPAWIPDGKAPRCMSCQTPFTAFRRRHHCRNCGGVFCGVCSNASAPLPKYGLTKAVRVCRECYVREVRSSRQAPAQPSQAHGQASRPQAASAS
What is the function of this protein?
Negative regulator of epidermal growth factor receptor (EGFR) signaling.
What are the official names of this protein?
Lateral signaling target protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the lst-2 family.
Protein: DSRB_SALNS
Sequence: MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGIWFFNESGHQDGIFVEKAEQD
What are the official names of this protein?
Protein DsrB.
What is the protein family that this protein belongs to?
Belongs to the DsrB family.
Protein: URE1_BURPS
Sequence: MTLRLSRRAYAEMYGPTTGDRIRLADTELLIEVERDHTLYGEEVKFGGGKVIRDGMGQSQLPAADVADTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEIIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMIGGGTGPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASRPQPLVEQIEAGAIGLKLHEDWGTTPAAIDNCLTVADDTDTQVAIHTDTLNEAGFVEATVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEANVLPSSTNPTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALTGDGARNDNFRAKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGVKPAMIIKGGMIAVAQMGDPNASIPTPQPVHYREMFATRGGALARTSLTFVSQLALDAGISARYGLAKRLVPVRGCRTVTKRDMIHNAWQPAIRVDPETYDVVADGALLTCEPAAVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSH_BPKVM
Sequence: MNLTEKWKDLLEAEGADMPEIATATKQKIMSKIFENQDRDINNDPMYRDPQLVEAFNAGLNEAVVNGDHGYDPANIAQGVTTGAVTNIGPTVMGMVRRAIPQLIAFDIAGVQPMTGPTSQVFTLRSVYGKDPLTGAEAFHPTRQADASFSGQAAASTIADFPTTGAATDGTPYKAEVTTSGGDVSMRYFLALGAVTLAVAGQMTATEYTDGVAGGLLVEIDAGMATSQAELQENFNGSSNNEWNEMSFRIDKQVVEAKSRQLKAQYSIELAQDLRAVHGLDADAELSGILANEVMVELNREIVNLVNSQAQIGKSGWTQGAGAAGVFDFSDAVDVKGARWAGEAYKALLIQIEKEANEIGRQTGRGNGNFIIASRNVVSALSMTDTLVGPAAQGMQDGSMNTDTNQTVFAGVLGGRFKVYIDQYAVNDYFTVGFKGSTEMDAGVFYSPYVPLTPLRGSDSKNFQPVIGFKTRYGVQVNPFADPTASATKVGNGAPVAASMGKNAYFRRVFVKGL
What is the function of this protein?
Major capsid protein that self-associates to form hexamers, building most of the capsid in association with pentons made of the capsid vertex protein and one dodecamer of the portal protein.
What are the official names of this protein?
Major capsid protein, Gene product 23, Major head protein, gp23.
What is the protein family that this protein belongs to?
Belongs to the T4 phage capsid protein family.
What are the subcellular locations of this protein?
[Major capsid protein]: Virion. Note=Part of the capsid icosahedric shell of the immature virion. SUBCELLULAR LOCATION: [Mature major capsid protein]: Virion. Note=Part of the icosahedric capsid shell of the mature virion.
Protein: PP2C6_PARTE
Sequence: MGPYLSQPKTEKTSVTGQNQVLQYAATHMQGWRNTMEDAHISDLNIEPDVHLFAVFDGHGGSEVAIFAERHFREELMKNKNYQQKNYEKALTETFFKIDKMLQEPSGLDELNKIRGVTDEASLAGCTANVALIVGKTLYVANAGDSRSFLNRDGKPFDMSKDHKPDDEQEKKRIERAGGFVSDGRVNGNLSLSRALGDLEYKKDNRFKPEEQIITALPDVKVTQLSAADKFLLMGCDGVFETWDHQQILNFINSELKNTQNLQKAAEKLLDQLLAKDTSLGTGCDNMTCILIQFK
What is the function of this protein?
Enzyme with a broad specificity.
What are the official names of this protein?
Probable protein phosphatase 2C 6, PP2C 6.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: RNC_AYWBP
Sequence: MKNIQILFQTLNIFPKNLVLYKQALTHSSYSNEQTPPQEDNERLEFLGDAIVGLLMADYLYSQSKEDEGIMTKKRAQAVCEKSLTIYAQKIELQNYLLLGKGEKNKDFNAKGIMADTFEALFGAIYLDLGYLTAKKVFHNIVLPHLAKTIYIIDFKTQLQEIVQSEKKTIQYKIVQEQGPAHSKNFVAEVYLEKNLLGTGEGSTKKSAEQKAAQQALSKVAKTKDLIKNKGVKEKEL
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMTA2_BOVIN
Sequence: MFGSSRGGVRGGQDQFSWEDVKTDKQRENYLGNSLMAPVGRWQKGRDLTWYAKGRANSAGLSREQELAAVRQAEQEALMAALGYKNVKKQPTGLSKEDFVEVCKREGGDPEKGVDRLLGLGSSSGSVGRVALSREDKEAAKLGLSVFTHHRVESSRPGTSLALAKKKLRSEEKVEPGPESHRKSRKEKKKKRHKKEKRKKEKDRGRRLDSSLAPAPIQHDSDSSTCCKKRRHDSD
What are the official names of this protein?
Multiple myeloma tumor-associated protein 2 homolog.
Protein: LPXA_SALCH
Sequence: MIDKSAFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVLKSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_ALKCK
Sequence: MLVSYKWLQEYIEIGDISPQEIAEKMTRSGIEIDFIHERNKGATNVVVGYVAEVAPHPDADKLNVCQVDIGEEERVQIVCGAPNVSSGQYVAVAKVGARLPGGIKIKKAKLRGQHSNGMICSLQELGIDSKLVPKGYVDGIYVFPETQSVEPGQDALAIFELNDSVLELDLTPNRSDCMHMLGVAYELAALYDRPIKMPKTKVKEVIESADGYINVSVENGEDTPFYQALVIKDVKIGPSPSWLQNRLMAAGIRPISNVVDVTNYVLLEYGQPLHAFDYHALASKSIHVRRAKAEEAFTTLDGEKRTLSPEQLVVTNGREPVALAGVMGGLHSEVTAATTTVVLEAAAFHPTVVRRSARLAGLRSDSSARFEKGINQERVSEAARRAAYLIQEIAGGIVLSGAAIADARVRSERVIALDLDKMNERIGTNLSIMEVAALMRRLQFPCEKVGSDLHVTVPHRRGDITIPEDLYEEVARLYGYDELPSTLPVGNTTQGKRTAEQAKRRKMEAYLRSAGLSEAISYALTSSEKAALFAAETIKPIQVAMPMSEERSTMRTSLLPHLYDICTYNLNRKNNDVLLYERGSVFLSEQETLTELPTEQERLAVLLSGTYMSHPWQGEKKAVDFYVLKGIAEGLMETLGLSEQIEYKPDVRPGFHPGRTANVLLKGESIGFLAQVHPSTQKALDLNETYVLELNVDALFAAETEALIYRGIPRYPAITRDMALVVSKETTAAELMAIIREAGGELLETVSIFDVYEGEHMESGKKSIAFSLTYRHAERTLTDEEASLAHEGIVAEVQKQTGAVLRA
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_PCV2
Sequence: MTYPRRRYRRRRHRPRSHLGQILRRRPWLVHPRHRYRWRRKNGIFNTRLSRTFGYTVKATTVRTPSWAVDMMRFNIDDFVPPGGGTNKISIPFEYYRIRKVKVEFWPCSPITQGDRGVGSTAVILDDNFVTKATALTYDPYVNYSSRHTIPQPFSYHSRYFTPKPVLDSTIDYFQPNNKRTQLWLRLQTSRNVDHVGLGTAFENSIYDQDYNIRVTMYVQFREFNLKDPPLKP
What is the function of this protein?
Self-assembles to form the virion icosahedral capsid with a T=1 symmetry.  This very small capsid (17 - 22 nm in diameter) allows the virus to be very stable in the environment and resistant to some disinfectants, including detergents.  Essential for the initial attachment to heparan sulfate moieties and chondroitin sulfate B of the host cell surface proteoglycans.  After attachment, the virus is internalized in a clathrin-, caveolae- and dynamin-independent, actin and Rho-GTPase-mediated pathway and traffics to the nucleus.  The capsid protein binds and transports the viral genome and Rep across the nuclear envelope (By similarity).
What are the official names of this protein?
Capsid protein.
What is the protein family that this protein belongs to?
Belongs to the circoviridae capsid protein family.
What are the subcellular locations of this protein?
Host nucleus. Virion.
Protein: RL36_ACTSZ
Sequence: MKVRASVKRICRNCKIVKREGVVRVLCTDPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: U1SBP_BOVIN
Sequence: MNDWMPIAKEYDPLKAGSIDGTDEDPHDRAVWRAMLARYTPNKGVTGDPLLTLFVARLNLQTKEEKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKDERSLLKAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESGQLRFGGRDRPFRKPINLPVVKNDQFREGKRERRERSRSRERHWDSRMRDHHDRGREKRWQEREPARAWPEGDWERERDFRDDRVKGREKRDRSK
What are the official names of this protein?
U11/U12 small nuclear ribonucleoprotein 35 kDa protein, U11/U12 snRNP 35 kDa protein, U1 snRNP-binding protein homolog.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBM_GOSBA
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: ATPF1_ROSDO
Sequence: MRNLSRLSVLALAMLAANPAFAAGGGISLKNTDFVVLLGLLVFIGILVYFKVPGMIGKMLDSRAEGIEAELNEARALREEAQSLLASYERKQREVQEQADRIVEAAKEEATIAAEQARADLEVSLARRMAAAEDQIASAQAAAIKEVRDQSVSIAIAAAQDVIAKQLTAADANALIDGAITEVEAKLH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GDF7_HUMAN
Sequence: MDLSAAAALCLWLLSACRPRDGLEAAAVLRAAGAGPVRSPGGGGGGGGGGRTLAQAAGAAAVPAAAVPRARAARRAAGSGFRNGSVVPHHFMMSLYRSLAGRAPAGAAAVSASGHGRADTITGFTDQATQDESAAETGQSFLFDVSSLNDADEVVGAELRVLRRGSPESGPGSWTSPPLLLLSTCPGAARAPRLLYSRAAEPLVGQRWEAFDVADAMRRHRREPRPPRAFCLLLRAVAGPVPSPLALRRLGFGWPGGGGSAAEERAVLVVSSRTQRKESLFREIRAQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAGTRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGCR
What is the function of this protein?
May play an active role in the motor area of the primate neocortex.
What are the official names of this protein?
Growth/differentiation factor 7, GDF-7.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RS14Z_DESPS
Sequence: MAKKSIIAKAKRKQKFAVREYNRCPLCGRPRAFIRKFGICRICFRKLASSGEVTGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: CRCB_PSEPF
Sequence: MVPLIVAVSVGGIAGTLLRFATGNWVNANWPRHFYTATLAVNIVGCLLIGVLYGLFLIRPEVPIEVRAGLMVGFLGGLTTFSSFSLDTVRLLESGQVPLALGYAAISVFGGLLATWAGLSLTKL
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARLY_SHIFL
Sequence: MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLSELQKFSQVIGEDVYPILSLQSCLEKRAAKGGVSPQQVAQAIAFAQARLE
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VNG2A_XENLA
Sequence: MDNDSQYSGYSYKSGHSRSSRKHRDRRERHRSKSREGSRGDKSVTIQAPGEPLLDNESTRGEDRDDNWGETTTVVTGTSEHSISHDDITRITKDMEDSAKLDCSRHLGVVIGGALALLSFLTPIAFMLLPQILWREDLEQCGTACEGLFISVAFKLLILLLGSWALFFRRPKAFFPRVFVFRALLMVLVFLLVVSYWLFYGVRILESRDKNYQGIVQYAVSLVDALLFVHYLAVVLLELRQLQPQFTIKVVRSTDGASRFYNIGHLSIQRVAVWILENYYHDFPVYNPALLNLPKSILSKKMSGFKVYSLGEENTTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRVRKRKARLVVAVEEAFTHIKRLQDEDQKNPREIMDPREAAQAIFASMARAMQKYLRTTKQQPYHTMESILHHLEFCITHDMTPKAFLERYLGPGPTIQYHKDRWLAKQWTLVSEEPVTNGLKDGVVFVLKRQDFSLVVSTKKIPFFKLSEEFVDPKSHKFVMRLQSETSV
What is the function of this protein?
Has a role in non-canonical Wnt/planar cell polarity (PCP) signaling; can recruit dvl/dsh and prickle from the cytoplasm to the plasma membrane.  Acts in a PCP complex to regulate the polarized assembly of fibronectrin on the surface of the mesoderm during gastrulation.  Regulates convergent extension cell movements in both dorsal mesoderm and neural tissue during gastrulation, without affecting cell fate.  Regulates neural fold closure during neurulation (PubMed:11867525, PubMed:11780127, PubMed:12421719).  May be required for cell surface localization of fzd3 and fzd6 in the inner ear (By similarity).
What are the official names of this protein?
Vang-like protein 2-A, Protein strabismus-A, Van Gogh-like protein 2-A, Xstrabismus-A, Xstbm-A.
What is the protein family that this protein belongs to?
Belongs to the Vang family.
Protein: YIDC_COREF
Sequence: MLDFLIYPVSGVMKLWHLLLHNGLGLDDSLAWFISLFGLVITVRAIIAPFTWKMYKSGRLTAQIRPKRVAIAEEFKGRHDEDSIREMQQKYKDLNKEYGINPFAGCVPTLIQIPVILGLYQVLLLMARPEGGLENPVPRSIGFLSAEEVQSFLQGRVFNVPLPAYVTMPAEQLTFLGTTREDVLSFVLPLFIVAAVFTAFNMALSTYRNIQTNDYASNISNGMFKAFLWLAVLAPLFPLVLGLTGPFPTAIALYWVANNLWTFGQTAIMHYIIERNYPLTEEFKEHHAAQRATYREQQRKKRAFLWTRRKNRLMMILTPHRAAELHAQNAEMTRERTERIRAEKATKKEIATKRRAAERKINQQKMEEARRRRQARRAGDKSNGEQPETDATDPSGK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIGB_PSEPW
Sequence: MSFFLRLAALLLLHTSIAQASHCPDWSTKQARTEVAQLRATLANWDDHYHRQGIALVADELYDQARHHLLHLQQCFGQEFTDPSPLASARGPIAHPVAHTGVEKLHDAAAVARWMTGKKGVWVQPKVDGVAVSLVYRQGRLVQLLSRGDGLQGHDWSRHIKDLDSITRQLPQPLDVVLQGELYLRLQAHVQAEAGSSNVRGTVAGMLARKQLGPEPGASIGLFVWDWPHGPDNQGERLTQLAAWGFPDSQRFSTAIDTPEEATHWRLHWYRSPLPFATDGVILRQDSRPPADRWQPNAPYWIAAWKYPFAQALAEVREVRFLIGRTGKVTPLLRLKPVTLDDRRISQVSLGSLARWRALDIRPGDQVAISLAGLTIPRFDQVVHRAVERQVLPVPEAEQYGQHSCWQASDGCQEQFIARLVWLSGKQGLAMPGTGKGTWKRLVQAGLVTSLTDWLTLDAQQLLSVPGISRKTATQLQRSFDIGRNRPFAQWRKGLGVPAPAQVPRDENWQTLAGRSASDWQTLPGIGATRATQLANFFTHEQVQRIATLLGTRGIDGFHGTDDVGSQ
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: PIMT_NITEU
Sequence: MSVRHSGIGMTSLRTRVRMVERLREQGIKDEVVLAAMGFIPRHLFVEAALASRAYEDVALPINYGQTISSPWIVGRMTELLRNGGSNSLRKILEIGTGCGYQTAVLAKIASEVYSIERIGPLLTRTRIRLRELGILNIHLKHADGMRGLPEAGLFDGIMMTAVIPEIPETLLEQLAMGGRMVFPKGNRKQYLCVIDHTTEGFVETILDEVMFVPILPGTINR
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS9_THISH
Sequence: MATTQNYGTGRRKTASARVFLRPGKGDIVVNGKPLDAYFGRETSRMVVRQPLEVAQAGNRFDVFATTAGGGANGQAGAIRLGIARALVEYDETLRGSMRAAGFMTRDAREVERKKVGLRKARRATQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: FOXG1_CERSI
Sequence: MLDMGDRKEVKMIPKSSFSINSLVPEAVQSDNHHASHGHHNSHHPQHHHHHHHHHHHPPPPAPQPPPPPPPPQQPPPAPQPSQARGVPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNGKYEKPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSDDVFIGGTTGKLRRRSTTSRAKLAFKRGARLTSTGLTFMDRAGSLYWPMSPFLSLHHPRASSTLSYNGTTSAYPSHPMPYSSVLTQNSLGNNHSFSTANGLSVDRLVNGEIPYATHHLTAAALAASVPCGLSVPCSGTYSLNPCSVNLLAGQTSYFFPHVPHPSMTSQSSTSMSARAASSSTSPQAPSTLPCESLRPSLPSFTTGLSGGLSDYFTHQNQGSSSNPLIH
What is the function of this protein?
Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
What are the official names of this protein?
Forkhead box protein G1, FoxG1.
What are the subcellular locations of this protein?
Nucleus.
Protein: FABH_STRA5
Sequence: MVFAKISQLAHYAPSQIIKNEDLSLIMDTSDDWISSRTGIKQRHISKNETTADLANKVAEQLIEKSGYSASQIDFIIVATMTPDSMMPSTAARVQAHIGASNAFAFDLSAACSGFVFALSTAEKLISSGSYQKGLVIGAETVSKVLDWTDRGTAVLFGDGAGGVLLEASKEKHFLAESLNTDGSRQGLQSSQVGLNSPFSDEVLDDKFLKMDGRAIFDFAIKEVSKSINHLIETSYLEKEDIDYLFLHQANRRILDKMSRKIDIARDKFPENMMDYGNTSAASIPILLSESYENGLLKLDGNQTILLSGFGGGLTWGSLIVKI
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.