PharMolix/UniProtQA huggingface dataset:
Protein: MNMG_BACMK
Sequence: MGYNAGSYDVIVIGAGHAGCEAGLAAARMGSKTLMLTINLDMVAFMPCNPSVGGPAKGIVVREIDALGGEMGRNIDKTHIQMRMLNTGKGPAVRALRAQADKFSYQHELKKTIEETPNLTLFQGLVERLIIEDGVCKGVITQAGAEYTAKTVVITTGTFLRGEIIMGDLKYSSGPNNQQPSITLSEHLEELGFDLVRFKTGTPPRVNSNTIDYSKTEIQPGDDKPRAFSFETTKFIMDQIPCWLTYTSTETHRLIDENLHRSAMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTQEVYVQGLSTSLPEDVQRAMLRTIPGLENVEMMRTGYAIEYDAIVPTQLWPTLETKKIKNLYTAGQINGTSGYEEAAGQGLMAGINAACRSLGKKEVILGRADAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTEVGREIGLIKEDRYERFTNKKLQIEQEKERLESIFIKPRPEVQELIRSIGGSELKDGIRASDLLRRPEVTYEHIHLLVPSEVALSDEITEQVEIQTKYEGYIEKSLQQVERMKKMENKKIPVDIDYDAISSLASEARQKLKDVRPLSMGQASRISGVNPADVSILLIYIEQGKIARVSNQ
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_NITHX
Sequence: MTSDRYNARDAEPRWQAAWDQQAIFATKNDDPREKYYVLEMFPYPSGRIHIGHVRNYTLGDVIARYMRAKGYNVLHPMGWDAFGLPAENAAIERKVAPKAWTYDNIKAMKKQLRSIGLSLDWAREFATCDPSYYKHQQKMFLDFLRAGLAEREKRKINWDPVDMTVLANEQVIDGRGWRSGAVVEQREMNQWVFKITKYSQELLEALDTLDRWPDKVRLMQRNWIGRSEGLLLRFALDPATTPNGEGELKIFTTRPDTLFGAKFMAIAPDHPLAQAAAKDNPALAEFIAECKRRGTAQAEIDTAEKMGFDTGIRAIHPFDPDWTLPVYVANFILMEYGTGAIFGCPAHDQRDLDFVNKYGLGNTPVVCPEGQDPKTLVITDTAYDGDGRMINSRFLDGMTAEAAKKEVAKRLESEMRGNMPVGERKVNFRLRDWGISRQRYWGCPIPVIHCPKCDVVPVPENDLPVTLPEDVTFDKPGNALDHHPTWKHVTCPQCGARATRETDTMDTFVDSSWYFARFTDPWNETAPTTPEIANRMMPVDQYIGGVEHAILHLLYSRFFTRAMKATGHLSMDEPFKGMFTQGMVVHETYRKADGGWASPDEVGIEAVGNGRRATLISTGEPVEIGAVEKMSKSKRNTVDPDDIIGSYGADTARWFMLSDSPPDRDVIWSEEGVQGASRFMQRLWRLVNESAEAGKAAPRDKPATFGTDALALRKAAHGALDKVSTGIERLHFNVCLANIREFANTLAETLARFGTRTSDLAPDIAWSLREAATILVQLFSPMMPHLSEECWHALGHTGLVSEARWPQIERDLLVEDTVTLPVQVNGKKRGEVTVASSAPNPEIETAVLALDAVRQALGGKPARKIIIVPQRIVNVVG
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_JANMA
Sequence: MKTYIVGGAVRDELLGVAVKDRDYVVVGATPEAMVAQGYTPVGKDFPVFLHPKTHAEYALARTERKTAPGYKGFVFHTDASVTLEEDLIRRDLTINAMAQDEDGSIVDPFGGKRDLELRIFRHVSPAFAEDPVRILRIARFAARFPEFTVAAETNTLMQDMVTAGEVDALVPERVWQELARGLMEVRPSRMFEVLRDCGALQRILPELDVLWGVPQPAQYHPEIDTGVHIMLVIDYAAGIKADLPVRCAALLHDLGKGVTLPDQWPRHHGHEMHSVKLVDTVSKRLKIPNDCRDLALMTAREHGNVGRALELRANTIVNLLERCDAFRKPQRFIEMLQASECDHRGRTGFADKPFPQKAYLQAALAAAQTVNGGEIAELTRQRYPDQAQRIPEAIHEARVQAVAAALKKQPGDPKE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: MCM32_MAIZE
Sequence: MEINEEAMAAHKRAFLDFLDQDVGKGVYMQAVRDMVQNKRHRLIIGMDDLRNHNLDLARRVIRTPGEYMQPASDAVSEVARNLDPKFLKEGERVMVGFSGPFGFHRVTPRDLMSSFIGTMVCVEGIVTKCSLVRPKVVKSVHFCPVTGDFLSREYRDITSFVGLPTGSVYPTRDDNGNLLVTEYGMCEYKDHQTLSMQEVPENSAPGQLPRTVDVIVEDDLVDCCKPGDRVSIVGVYKALPGKSKGSVSGVFRTVLIANNVSLLNKEANAPVYTREDLKRMKEISRRNDTFDLLGNSLAPSIYGHLWIKKAVVLLMLGGVEKNLKNGTHLRGDINMMMVGDPSVAKSQLLRAVMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAMVLADRGVVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVIAAANPIYGTYDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDPEIDRQISEHVARMHRYCTDDGGARSLDKEGYAEEDDGDANAAIFVKYDRMLHGQDRRRGKKSKQDRLTVKFLKKYIHYAKNLIQPRLTDEASDHIATSYAELRDGSANAKSGGGTLPITARTLETIIRLSTAHAKMKLRHEVLKSDVEAALQVLNFAIYHKELTEMEEREQREMEMKQQADHDAGATGGTVDGHGSSGNDPMDVDVGSNDQNVSAERIEAFEALLGQHVLANHIDQMSIDDIEQMVNRESTAPYTRSQVEFILERMQDANRVMIRDGVVRII
What is the function of this protein?
Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle.  Required for DNA replication and cell proliferation (By similarity).  May act as a component of the MCM complex which is the putative replicative helicase of the replication licensing system in eukaryotic cells.
What are the official names of this protein?
DNA replication licensing factor MCM3 homolog 2, Replication origin activator 2, ROA-2.
What is the protein family that this protein belongs to?
Belongs to the MCM family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IRT2_ORYSJ
Sequence: MMMSSSQTPVRIAFVFLVILAATDAHSDHRTPPPACGGAAVGGECHSVARALRLKLIAIPAILAASVAGVCLPLFARSVPALRPDGGLFAVVKAFASGVILGTGYMHVLPDSFNDLTSPCLPRKPWSEFPFAAFVAMLAAVFTLMVDSLMLTFHTRGSKGRASSAVAHHGDHGHCHAHALGQADVAALSTTEAADQGSGDVEAGNTTKAQLLRNRVIVQVLEMGIVVHSVVIGLGMGASQNVCTIRPLVAALCFHQMFEGMGLGGCILQAGYGGRTRSALVFFFSTTTPFGIALGLALTRVYSDSSPTALVVVGLLNAASAGLLHYMALVELLAADFMGPKLQGNVRLQLAASLAILLGAGGMSVMAKWA
What is the function of this protein?
Iron transporter that may play a role in the uptake of iron from the rhizosphere across the plasma membrane in the root epidermal layer.
What are the official names of this protein?
Fe(2+) transport protein 2, Fe(II) transport protein 2, Iron-regulated transporter 2, OsIRT2.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RF1_MESH2
Sequence: MEKKMFNSLMKIHQKYQDLKQLLETDQILNDQKQYLQIAKEIASITEIIEVFQKFLDDQKVLEDAKTILIQEDDPELIQLAKVEIATMSKNIEEYEKKLLILMLPKDKNDEKDVIVEIRGAAGGDEANIFVGDLFKMYHKWADSQKAKVKVLSSSLALAGGFSQIIFQISGQKIYSKLKFESGVHRVQRVPATETMGRIHTSTATVTVMPKIDEKIEIEINPSDLKIDTYRSSGAGGQSVNTTDSAVRITHIPTGIVVTSQDERSQIGNKEIAMGILKSKIYNLELQKQQQKQSDFRKLAGSGARSEKIRTYNYPQDRLTDHRINFSTSLKPIIQGNLNPIIEALLAQEKTELILQNYANK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SERF2_PLEMO
Sequence: MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK
What is the function of this protein?
Positive regulator of amyloid protein aggregation and proteotoxicity (By similarity).  Induces conformational changes in amyloid proteins, such as HTT, driving them into compact formations preceding the formation of aggregates (By similarity).
What are the official names of this protein?
Small EDRK-rich factor 2.
What is the protein family that this protein belongs to?
Belongs to the SERF family.
Protein: DEF_KLEP7
Sequence: MAVLQVLHIPDERLRKVAEPVKEVNAEIQRIVDDMFDTMYAEEGIGLAATQVDIHQRIIVIDVSENREEQLVLINPEMLEKDGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLRSRA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: UVRC_METHJ
Sequence: MVSIDLTTIPEEPGCYQFKDETGTILYVGKAKNLKKRVSSYFQKKSITPRIDILVSLIRDIDVIVTSSEVEALILENNLIKKYQPKYNIDLKDAKSYAFIQISNDPFPRIGIARDRTVKKTGTLYGPFVSAAERDQILKFVKQTFHLRTCKKMTKRACLRSHLGTCAAPCTGKISEPEYQYLVKSADYLLKGKSQDLIYDLRKEMETFAAAEEYEKALVIRDRIAAIENLSERQYVQRQKKSDEHIINYLVSGDTVYLILFHVERGSLTSKEEFVFPETEDFLDEFILQYYSSTKPPNELILPSLPGSGMEEYLTHIRGSHVTLTIPKQGEKKHLLDLAYKNLEVSFFTGKMRLAELGEALHMDTAPEVIECFDISHLRGTGTVASMVSFRDGKPDKRNYRRYKINSAGPSDDYAAMAEVVKRRYSRLLREKSPMPDLIVVDGGPGQLKSAHAILEELSLPIPIISIAKREEEIYIPGRNTPLSIQKKSPASLLIQEIRDEAHRFAITYQKKLRQKSIKE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZDH13_MOUSE
Sequence: MEGPGLGSQCRNHSHGSHVPGFGRHGICVHENKELAKAKEILPLIEDSSNCDIVKATQYGIFERCKELVEAGYDVRQPDRENVSLLHWAAINNRLELVKFYISKGAVIDQLGGDLNSTPLHWAIRQGHLPMVILLLQHGADPTLIDGEGFSSIHLAVLFQHMPIIAYLISKGQSVNMTDVNGQTPLMLSAYKVIGPEPTGFLLKFNPSLSVVDKTHQNTPLHWAVAAGNVSAVDKLLEAGSSLDIRNAKGETPLDMALQSKNQLISHMLRTEAKMRANKQFRLWRWLHKCELFLLLILSMITLWAVGYILDFNSDSWLLKGCLLVALFFLTSLFPRFLVGYKNLVYLPTVFLLSSIFWIFMTWFILFFPDTAGSPLYFAFIFSIMAFLYFFYKTWATDPGFTKASEEERKVNIVTLAETGSLDFRTFCTSCLIRKPLRSLHCHVCNSCVARFDQHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGSFVYWSNHCATTFKEDGLWTYLNQIVACSPWVLYIFMLAAFHFSWSTFLLINQLFQIAFLGLTSHERISLLKQSRHMKQTLSLRKTPYNLGFTQNLADFFQCGCFGLVKPCIIDWTSQYTMVFHPAKEKVLRSV
What is the function of this protein?
Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (PubMed:18794299, PubMed:19299482).  Palmitoyltransferase for HTT and GAD2 (PubMed:19299482, PubMed:20548961).  May play a role in Mg(2+) transport (PubMed:18794299).
What are the official names of this protein?
Palmitoyltransferase ZDHHC13, Huntingtin-interacting protein 14-related protein, HIP14-related protein, Zinc finger DHHC domain-containing protein 13, DHHC-13.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Low extracellular Mg(2+) induces increase in Golgi and in post-Golgi vesicles.
Protein: NTPP_TRIEI
Sequence: MKIPSVILASSSSARLRLLKTVGINPIVMPSNFDESTIKLKEPRQLVETLAQAKAETIANSIMKEKLPEKQSNLILGCDSVLVIEDQIYGKPNDKQEAITRWQKMRGQVGQLYTGHALIDLSQNKTIVLCRMTKVHFSHVNDQEIEAYVATEEPLKCAGCFAIDGIGGLFIEKIDGCHTNVIGLSLPLFRVMLNNLGYQVSNFW
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_PSYA2
Sequence: MDTLFMTTVTATPAIKEDRILILDFGSQYSQLIARRVRDSGVFCEMFPYDIDTQRITDFGAKGIILSGGPESVHAENSPRINDAVFELGVPVLGICYGMQAMAERFGGKVHASDIHEFGAATINIDGKSTLTNGIEDAAAKLNVWMSHGDKVVDAPQGFDIVASTPSCPIAIMADDSRHYYGLQFHPEVTHTAQGQALLGRFVHEICDCAGSWTPDNIIDMRIEQLKKQIGDKQVLLGLSGGVDSSVVAALLHKAIGDQLTCVFVDTGLLRLHEGDQVMQIFAENMGVKVIRVDAEELFLTALAGESDPEAKRKIIGKTFIDVFANSAREISEQSDGKVIEFLAQGTIYPDVIESAKSHQGKAHVIKSHHNVGGLPDDLAFELVEPLRDLFKDEVRKLGITLGLPAKMINRHPFPGPGLGVRILGEVTKEFADILRSADAIFMEELEKSGWYEKTAQAFAVFQPIKSVGVVGDGRRYAWVIALRAVETVDFMTARFAHLPYDLIETVSNRIMNEIAEVSRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ARPA_PSEPU
Sequence: MQFKPAVTALVSAVALATLLSGCKKEEAAPAAQAPQVGVVTIQPQAFTLTSELPGRTSAYRVAEVRPQVNGIILKRLFKEGSEVKEGQQLYQIDPAVYEATLANAKANLLATRSLAERYKQLIDEQAVSKQEYDDANAKRLQAEASLKSAQIDLRYTKVLAPISGRIGRSSFTEGALVSNGQTDAMATIQQLDPIYVDVTQSTAELLKLRRDLESGQLQKAGNNAASVQLVLEDGSLFKQEGRLEFSEVAVDETTGSVTLRALFPNPDHTLLPGMFVHARLKAGVNANAILAPQQGVTRDLKGAPTALVVNQENKVELRQLKASRTLGSDWLIEEGLNPGDRLITEGLQYVSPRRRGEGQRCHQRQEAGRP
What is the function of this protein?
The periplasmic linker protein component of an antibiotic efflux pump.  Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline.  Is not involved in organic solvent efflux.
What are the official names of this protein?
Antibiotic efflux pump periplasmic linker protein ArpA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: ACR7_ARATH
Sequence: MELSDCSNEYEKLVVRMNMPRVVIDNGVCPNSTVVKIDSARSPGILLESVQLLTDMNLWIKKAYISSDGKWNMDVFHVSDLNGDKLTDENLIRYIEKSIETSHYCKTEGYTGLTALELTGTDRVGLLSEVFAVLADLECDVVEAKAWTHNGRIASMIYVKDGNSGTPIDGDSDRVQRVEGQLRNLLKADDGYQNDTRTCVSYGGNTHMERRLHQRMFMDRDYEKKFDIEKSPIVSVQNLPKRGYSVVNLQCKDRMKLLFDVVCTLTDMAYIVFHAAIRTVGETAFLEFYVRHSDGHPVSSEPERQRLIQCLQAAIERRTVKGVRLELCTADRPGLLAEVTRILRENGLNIARAEISTKDSIARNVFYVTDANGNLIDPEIIKSIREKIGIDDLSVKEPFPISCREAVEKEQHIEPQDHQGRYGGGTVLVSLGSLVMRNLYHLGLIKSYF
What is the function of this protein?
May bind amino acids.
What are the official names of this protein?
ACT domain-containing protein ACR7, Protein ACT DOMAIN REPEATS 7.
Protein: SYE_DEHMC
Sequence: MTNEVRVRYAPSPTGYPHLGNIRTAMFNWLFARHNGGKFIVRIEDTDRERYVEGAVESILESLNWLGLDWDEGPDKGGDYGPYYQSERLPLYRKAAEKLVAEGKAYYCHCSSEKLDKMREDQIARKEPPGYDRCCRDMGLGQKEGAVIRFKIPLDGQTAFTDLIRGEVTFDNAKQDDFVILKSDGFPTYHLASVVDDHAMQISHVLRAEEWLPSTPKHLMLYKALGYTPPLYAHLPMILGPDRSKLSKRHGATSTIEYKQAGYLPETMVNFLSLLGWAYDDKTELFSREQLIEYFCLEKVSKTAAIFNYEKLDWMNGMYIRTLSAQDLACRAMPFLEKDVRIAASGHLNLDYTVKVMPLIQERAKKLNELAELCWFIYSDDISYDPALLIDKKLTKETSLSALKAANARLEALPNFDAASMEEHIRPLAAELELKPGQLFGMLRTASTGQQVAPPLFQTMEVLGRQRCLWRIAMAIARLSEMPFQRS
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXA_SHIFL
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLTSICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DSK2_SCHPO
Sequence: MTNISLTIKAANDQKYAVTVDSESSVLALKEAIAPVADIEKERQRLIYAGRVLKDEESLKTYKIQDGHSIHLVKTLGQNPAAAATNVSDRTQQVPTNIQAGQGANNPLANLTSARYAGFNIPMPSASMFGPNPENPVPPSTEELANMLSNPMVQSSINEMFSNPQMLDMIINSSPHLRNAPPYVRQMMQSPEFRRAMTDPDTMRQMAQLHQQMGAAGIDPMSLMGGGLGGAGLGGLGGAGLGGFGGANNATAGIAGAAPVDQTAAANTIQNLLNNLGGAGFGAGLGDAGLGAGLGGAASPPAPAQDTRPPEERYAEQLSQLNEMGFVDFERNVQALRRSGGNVQGAIESLLSDL
What is the function of this protein?
Protects ubiquitin chains against dissambly by deubiquitinating enzymes thereby promoting protein degradation.
What are the official names of this protein?
Deubiquitination-protection protein dph1.
Protein: BGAL_THETH
Sequence: MLGVCYYPEHWPKERWKEDARRMREAGLSHVRIGEFAWALLEPEPGRLEWGWLDEAIATLAAEGLKVVLGTPTATPPKWLVDRYPEILPVDREGRRRRFGGRRHYCFSSPVYREEARRIVTLLAERYGGLEAVAGFQTDNEYGCHDTVRCYCPRCQEAFRGWLEARYGTIEALNEAWGTAFWSQRYRSFAEVELPHLTVAEPNPSHLLDYYRFASDQVRAFNRLQVEILRAHAPGKFVTHNFMGFFTDLDAFALAQDLDFASWDSYPLGFTDLMPLPPEEKLRYARTGHPDVAAFHHDLYRGVGRGRFWVMEQQPGPVNWAPHNPSPAPGMVRLWTWEALAHGAEVVSYFRWRQAPFAQEQMHAGLHRPDSAPDQGFFEAKRVAEELAALALPPVAQAPVALVFDYEAAWIYEVQPQGAEWSYLGLVYLFYSALRRLGLDVDVVPPGASLRGYAFAVVPSLPIVREEALEAFREAEGPVLFGPRSGSKTETFQIPKELPPGPLQALLPLKVVRVESLPPGLLEVAEGALGRFPLGLWREWVEAPLKPLLTFQDGKGALYREGRYLYLAAWPSPELAGRLLSALAAEAGLKVLSLPEGLRLRRRGTWVFAFNYGPEAVEAPASEGARFLLGSRRVGPYDLAVWEEA
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 42 family.
Protein: FMO1_HUMAN
Sequence: MAKRVAIVGAGVSGLASIKCCLEEGLEPTCFERSDDLGGLWRFTEHVEEGRASLYKSVVSNSCKEMSCYSDFPFPEDYPNYVPNSQFLEYLKMYANHFDLLKHIQFKTKVCSVTKCSDSAVSGQWEVVTMHEEKQESAIFDAVMVCTGFLTNPYLPLDSFPGINAFKGQYFHSRQYKHPDIFKDKRVLVIGMGNSGTDIAVEASHLAEKVFLSTTGGGWVISRIFDSGYPWDMVFMTRFQNMLRNSLPTPIVTWLMERKINNWLNHANYGLIPEDRTQLKEFVLNDELPGRIITGKVFIRPSIKEVKENSVIFNNTSKEEPIDIIVFATGYTFAFPFLDESVVKVEDGQASLYKYIFPAHLQKPTLAIIGLIKPLGSMIPTGETQARWAVRVLKGVNKLPPPSVMIEEINARKENKPSWFGLCYCKALQSDYITYIDELLTYINAKPNLFSMLLTDPHLALTVFFGPCSPYQFRLTGPGKWEGARNAIMTQWDRTFKVIKARVVQESPSPFESFLKVFSFLALLVAIFLIFL
What is the function of this protein?
Broad spectrum monooxygenase that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including xenobiotics (PubMed:32156684).  Catalyzes the S-oxygenation of hypotaurine to produce taurine, an organic osmolyte involved in cell volume regulation as well as a variety of cytoprotective and developmental processes (PubMed:32156684).  In vitro, catalyzes the N-oxygenation of trimethylamine (TMA) to produce trimethylamine N-oxide (TMAO) and could therefore participate to the detoxification of this compound that is generated by the action of gut microbiota from dietary precursors such as choline, choline containing compounds, betaine or L-carnitine (By similarity).
What are the official names of this protein?
Flavin-containing monooxygenase 1, Dimethylaniline monooxygenase [N-oxide-forming] 1, Dimethylaniline oxidase 1, Fetal hepatic flavin-containing monooxygenase 1, FMO 1, Trimethylamine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FMO family.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: PQQA_RUEPO
Sequence: MAWTAPKLREVNCGMEINMYAPAEDEGGRGTDPIL
What is the function of this protein?
Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis.  PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide.
What are the official names of this protein?
Coenzyme PQQ synthesis protein A, Pyrroloquinoline quinone biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the PqqA family.
Protein: PDXJ_WOLSU
Sequence: MLLGVNIDHIATLREARKINEPDPLEAVFLAKRAGAFQITIHLREDRRHIHDYDVERIVESSFLPVNVECSTDKQIVDLLCELRPHRITLVPEKREEVTTEGGLDLLGRFEILKSRIAQFRENDIAVSLFVDPDITSIELSKELGADMVELHTGTFANLHLMLRSNLPKTPHAIPALEMDRRSLSLAYRESLLTLQKAAQKANTLGIEVAAGHGLNYQNVSEIVKIPEIIELNIGHSLIARSIFTGFEAAVREMVELLGRGD
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_STUS1
Sequence: MKGLIQRVRHARVEVAGEIVGAIDQGLLVLVGVEREDDQARADKLLHKLLNYRVFGDEQGKMNRSLKDIGGGLLLVSQFTLAADTRSGLRPSFSSAAPPAHGEALYDYLLARARDQHPEVACGRFGAEMQVHLVNDGPVTFLLES
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
Protein: NDUAC_HUMAN
Sequence: MELVQVLKRGLQQITGHGGLRGYLRVFFRTNDAKVGTLVGEDKYGNKYYEDNKQFFGRHRWVVYTTEMNGKNTFWDVDGSMVPPEWHRWLHSMTDDPPTTKPLTARKFIWTNHKFNVTGTPEQYVPYSTTRKKIQEWIPPSTPYK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, 13 kDa differentiation-associated protein, Complex I-B17.2, CI-B17.2, CIB17.2, NADH-ubiquinone oxidoreductase subunit B17.2.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA12 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CH601_CERS4
Sequence: MAAKDVKFDTDARDRMLRGVNILADAVKVTLGPKGRNVVIDKSFGAPRITKDGVSVAKEIELSDKFENMGAQMVKEVASRTNDEAGDGTTTATVLAQAIIKEGLKAVAAGMNPMDLKRGIDLATSKVVEAIKAAARPVNDSHEVAQVGTISANGEAQIGRFIADAMQKVGNEGVITVEENKGLETEVEVVEGMQFDRGYLSPYFVTNADKMTAELDDVYILLHEKKLSSLQPMVPLLEAVIQSQKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLQDIAILTGGQVISEDLGMKLENVTIDMLGRAKKISINKDNTTIVDGNGDKAEIDARVAQIRNQIEETSSDYDREKLQERVAKLAGGVAVIRVGGMTEVEVKERKDRVDDALNATRAAVQEGIVVGGGVALIQGGKALDGLTGENPDQNAGITIVRRALEAPLRQIAQNAGVDGSVVAGKVRESNEKSFGFNAQTEEYGDMFKFGVIDPAKVVRTALEDAASVASLLITTEAMIADKPEPKSPAGGPGMGGMGGMDGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED18_DANRE
Sequence: MEAPPVTVMPVTGGTINMMEYLLQGSVLDQSLESLLHRLRGLCDNMEPESFADHELVYLLKGQQGNPFILRARRSLLDPSVPWHLRYLGQPEVGDKSRHALVRNCVDVAASHSLPDFLNEMGFRMDHEFVAKGQVFRKGVMKVVVSKLSRVLVPGNTDNTEPLSLSYLVELSVLAPAGQDTVSEDMRSFAEQLKPLVHLEKIDPKRLM
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.