PharMolix/UniProtQA huggingface dataset:
Protein: GCSP_VIBVU
Sequence: MTELLQSLNTQHEFVGRHNGPNHADQQKMLSTINAESLDALIAQTVPAQIRLEKPMQLAEAQSEADMLASIKKFADLNQVKRTFIGQGYYNTFTPNVILRNVLENPGWYTAYTPYQPEISQGRLESLLNYQQMVMDLTGMDIANASLLDEATAAAEAMTLCQRAGKSKSKVFFVADDVHPQTIEVIKTRAKYFGFDVVIGNVDSLPQTEAFGALLQYPSTTGEVRDLTDVITQAQANKTLVSVATDLLASALVKPAGEMGADVVIGSAQRFGVPMGYGGPHAAFMATREQHKRTMPGRVIGVSIDAKGNQALRMAMQTREQHIRREKATSNICTAQALLANMASFFAVYHGEVGIRTIARRTHHMTAILAAGLTKSGYELAHNAFFDTITINTGDNTQALYAKAQAADINLRLLDGQIGISFDETTTVADIDALFAIFDVKESVNALSTDIAGNEFAAIPEACRRTSRFLTHPVFNTHHSETQMMRYLKQLENKDFSLTHGMIPLGSCTMKLNAAAEMIPVTWPEFGALHPFAPIEQAAGYTALAEDLKAKLCEITGYDAFSLQPNSGASGEYAGLIAIQRYHESRGEGHRNVCLIPSSAHGTNPATAAMVSMKVVVVKCDENGNIDLVDLAAKIEKHQENLSSIMITYPSTHGVYEEQVKEVCEMVHAAGGQVYLDGANMNAQVGLTSPGFIGSDVSHLNLHKTFCIPHGGGGPGMGPIGVKSHLAPFLPGHIENGVEGKEFAVSAADLGSASILPISWAYIAMMGADGLTEATKVAILNANYVMERLRPHYPVLYRGTNGRVAHECIIDIRPLKEETGISEEDIAKRLMDYGFHAPTMSFPVAGTLMVEPTESEDLEELDRFCDAMIAIREEMTKVKNGEWPLENNPLVNAPHTQVDLMEEQWDRPYPREIACFPSAATKRSKYWPTVNRVDNVYGDRNLVCSCPGIENYEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RL27_ACET2
Sequence: MIKANLQLFAHKKGVGSTRNGRDSESKRLGVKRGDGQFVKAGNILVRQRGTKIHPGLNVGKGKDDTLFALVDGRVKFSRLGKDRKQVSIIPA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: DLTB_STRT2
Sequence: MIDFLKQLPHLEPYGNPFYFIYLGIALLPIFIGLFFKKRFAIYECLVSITFIVLALTGTHASQILALLFYIVWQIIWVYSYKRYRSQRDNKWVFYLHSFLVVLPLILVKVEPTINGTQSLLNFLGISYLTFRAVGMIIEMRDGVLKEFTLGEFLRFMLFMPTFTSGPIDRFKRFNEDYQSIPNRDELLNMLEQAVKYIMLGFLYKFVLAQIFGSMLLPPLKAQALSQGGIFNLPTLGVMYVYGFDLFFDFAGYSMFALAVSNLMGIKSPINFDKPFISRDMKEFWNRWHMSLSFWFRDFVFMRLVIVLMRNKVFKNRNTTSNVAYIINMMVMGFWHGITWYYIAYGIFHGIGLVINDAWLRKKKTINKDRKKAGLKPLPENKWTKALGIFITFNTVMLSFLIFSGFLNDLWFTKK
What is the function of this protein?
O-acyltransferase that catalyzes D-alanylation of both teichoic acid and lipoteichoic acid (LTA) (PubMed:30283133).  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall (PubMed:30283133).  Catalyzes D-alanylation from DltC carrier protein (PubMed:30283133).
What are the official names of this protein?
Teichoic acid D-alanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LUXS_CLOD6
Sequence: MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPNVESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEEALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: LABER_LAVAN
Sequence: MEARRSGNFESSIWDDDYIQSLTSSYTGKMYVDKSEKLKIEVKMMMDEATDELEQLELINDLQRLGISYHFKDGIAKMLNNIYKSDSKYMEKDLHLTALKFRLLRQHGYRVPQDVFSSFMDDEGNFEAWVVEDVSVLVSLYEASHISVEGESILDMAKDFSSHHLTEMVEQIGEACLAEQVKRTLELPLHWRVGRLEARWFVQAYETRPNSNPTLVELAKLDFNMVQAKYQDELKRCSRWYEETGLPEKMSFARHRLAECFLWSLGFIPDPHHGYSREIMTKIAVLITITDDIYDIYGALEELQEFTEAFERWDINSLDLLPEYMQICFLAIFNSANELGYQILRDQGLNIIPNLKRSWAELSRAYYLEARWFHNGFVPTTDQYLNTAWISISGPLLLSYGYLTTTNPINNKELKSLEKHPSIIRWPSMVLRLADDLGTSSEEIKRGDVSKSIQCYMNETGCCEGDARHHVKSLIEVALKRMNDEILMEKPFKSFDTNAMNLARISLCFYQYGDGFGKPHSDTIKNLVSLIVLPFHMP
What is the function of this protein?
Catalyzes a mixture of sesquiterpenoids from (2E,6E)-farnesyl diphosphate.  Catalyzes the formation of exo-alpha-bergamotene, as well as (E)-nerolidol, (Z)-alpha-bisabolene, (E)-beta-farnesene and beta-sesquiphellandrene.  Also has activity towards geranyl diphosphate, but to a much lesser extent.
What are the official names of this protein?
Exo-alpha-bergamotene synthase, LaBERS, Trans-alpha-bergamotene synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
Protein: SYP_PARXL
Sequence: MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPIGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWQESGRWEKYGPELLRFKDRKQSDFVIGPTHEEVVTDIARNQIKSYRQLPVNFYQVQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDMDGLRESYRKMYDAYVRIFTRLGLDFRAVAADNGSIGGSGSHEFHVIAETGEDAIAYCPTSDFAANVEAAEALPLHAERAAPAEEMKKTATPGKAKCEAVAELLNIPLERTIKSIILATENEGAEPTIWLLMLRGDHDLNEIKASKLPGLADFRMATEAEIIETFGTPPGYLGPLNTKKPVKVVADRTVANMSDFVVGSNEVDYHTTGVNWGRDLPEPVVADIRNVKKGDPSPDGKGVIDICRGIEVGHVFQLGTKYSEAMNATCLDETGKPRPMEMGCYGIGVTRILGAAIEQNFDDRGIIWPESIAPFEVVLCPMGYDRSEAVREAADKLYATLLEAGIDVILDDRGERPGVMFADWELIGVPHRLVIGDRGLKDGKLEYQGRRDAEATLLPVEDAAQTVIAKVRAALAR
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOAB_ECOLI
Sequence: MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLAQIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNPKYKVEIKIVAAV
What are the official names of this protein?
RutC family protein YoaB.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: COPIA_DROME
Sequence: MDKAKRNIKPFDGEKYAIWKFRIRALLAEQDVLKVVDGLMPNEVDDSWKKAERCAKSTIIEYLSDSFLNFATSDITARQILENLDAVYERKSLASQLALRKRLLSLKLSSEMSLLSHFHIFDELISELLAAGAKIEEMDKISHLLITLPSCYDGIITAIETLSEENLTLAFVKNRLLDQEIKIKNDHNDTSKKVMNAIVHNNNNTYKNNLFKNRVTKPKKIFKGNSKYKVKCHHCGREGHIKKDCFHYKRILNNKNKENEKQVQTATSHGIAFMVKEVNNTSVMDNCGFVLDSGASDHLINDESLYTDSVEVVPPLKIAVAKQGEFIYATKRGIVRLRNDHEITLEDVLFCKEAAGNLMSVKRLQEAGMSIEFDKSGVTISKNGLMVVKNSGMLNNVPVINFQAYSINAKHKNNFRLWHERFGHISDGKLLEIKRKNMFSDQSLLNNLELSCEICEPCLNGKQARLPFKQLKDKTHIKRPLFVVHSDVCGPITPVTLDDKNYFVIFVDQFTHYCVTYLIKYKSDVFSMFQDFVAKSEAHFNLKVVYLYIDNGREYLSNEMRQFCVKKGISYHLTVPHTPQLNGVSERMIRTITEKARTMVSGAKLDKSFWGEAVLTATYLINRIPSRALVDSSKTPYEMWHNKKPYLKHLRVFGATVYVHIKNKQGKFDDKSFKSIFVGYEPNGFKLWDAVNEKFIVARDVVVDETNMVNSRAVKFETVFLKDSKESENKNFPNDSRKIIQTEFPNESKECDNIQFLKDSKESENKNFPNDSRKIIQTEFPNESKECDNIQFLKDSKESNKYFLNESKKRKRDDHLNESKGSGNPNESRESETAEHLKEIGIDNPTKNDGIEIINRRSERLKTKPQISYNEEDNSLNKVVLNAHTIFNDVPNSFDEIQYRDDKSSWEEAINTELNAHKINNTWTITKRPENKNIVDSRWVFSVKYNELGNPIRYKARLVARGFTQKYQIDYEETFAPVARISSFRFILSLVIQYNLKVHQMDVKTAFLNGTLKEEIYMRLPQGISCNSDNVCKLNKAIYGLKQAARCWFEVFEQALKECEFVNSSVDRCIYILDKGNINENIYVLLYVDDVVIATGDMTRMNNFKRYLMEKFRMTDLNEIKHFIGIRIEMQEDKIYLSQSAYVKKILSKFNMENCNAVSTPLPSKINYELLNSDEDCNTPCRSLIGCLMYIMLCTRPDLTTAVNILSRYSSKNNSELWQNLKRVLRYLKGTIDMKLIFKKNLAFENKIIGYVDSDWAGSEIDRKSTTGYLFKMFDFNLICWNTKRQNSVAASSTEAEYMALFEAVREALWLKFLLTSINIKLENPIKIYEDNQGCISIANNPSCHKRAKHIDIKYHFAREQVQNNVICLEYIPTENQLADIFTKPLPAARFVELRDKLGLLQDDQSNAE
What are the official names of this protein?
Copia protein, Gag-int-pol protein.
Protein: ICMS_LEGPH
Sequence: MERDISKCMAKIAASMNAKFYLNDRFVSFDEVFSETGLLPAIAKRADQLCSLCLGYGLGATYDESEGALLGIRVVFDEVTPNVLRLLCMTDVMNELIQGGPSRDYTPLDELMYD
What is the function of this protein?
Component of the Dot/Icm type IVB secretion system (T4BSS), which is used to inject bacterial effector proteins into eukaryotic host cells (PubMed:15661013, PubMed:18069892, PubMed:17040490, PubMed:22694730, PubMed:32513920).  Part of a subcomplex which recruits effector proteins and delivers them to the core transmembrane subcomplex (PubMed:23028312, PubMed:32513920).  The IcmS/IcmW protein complex plays an important role in protein translocation by interacting with multiple Dot/Icm effector proteins to facilitate their translocation into host cells (PubMed:15661013, PubMed:18069892).  Interaction promotes conformational changes in the effector protein, which may facilitate display of a C-terminal translocation signal (PubMed:18069892).  May maintain the substrates in a translocation competent form (PubMed:23028312).  Required for intracellular growth in host cells, replicative phagosome formation and phagosome trafficking (PubMed:11115108).  IcmS is required for IcmW stability (PubMed:15661013, PubMed:29203674).
What are the official names of this protein?
Type 4 adapter protein IcmS, Intracellular multiplication protein S, Secretion adapter protein IcmS.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associates with the inner membrane at the poles in a DotL/DotM/DotN-dependent manner.
Protein: DAPH_STRT2
Sequence: MTAQKMSAQEIIAFIGNAEKKTNVKVTFEGELATAVPSSVTKLGNVLFGDWKDIEPLLANLTENKDYVVEQDGRNSAVPLLDKRHLNARIEPGAIIRDQVTIEDNAVVMMGAVINIGAEIGAGTMIDMGAILGGRATVGKNSHIGAGAVLAGVIEPASAEPVRIGDNVLVGANAVVIEGVQVGNGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDEKTQQKTALEDALRNL
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: EX7L_HAHCH
Sequence: MSELSPHSPFSVTELNRQVRRLLEVSFMQVWVTGEISNFSCPSSGHWYFSLKDDKAQVRCAMFRNRNMFVKQRPRDGEAVTLRAKVSLYEGRGEFQLIAESMELAGEGELRRAFEELKLKLSREGLFEESRKRPLPAMPKQVGVITSPTGAAVRDILTVLERRFPAIPVLLFPVPVQGKEAGPAIVAAIASANRLNCCDVLIVGRGGGSLEDLWAFNEEPVARAIAASAIPVVSAVGHETDITIADLVADLRAPTPSAAAEKVSPDQAEWKHRFLIYEQRLDAAAQRLLRQEGLRLNQLRGRLKHPGRRLQESAQRLDDLEVRLHRQAQNLLSVRRNQLTHLRDRLLASSPRQSLKNRYATVDALNHRLQTAVLSVLRHKSQHFAKLCGHMEAVSPIATLARGYAIVSDENGQIIRSEKEVRTGQKVKARLSDGEIHCEVVASV
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDK1L_PONAB
Sequence: MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPTLKVADGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
What are the official names of this protein?
Serine/threonine-protein kinase PDIK1L, PDLIM1-interacting kinase 1-like.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPS_SALA4
Sequence: MGKTNDWLDFDQLVEDSVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: PHNW_PSEPK
Sequence: MSNAPILLTPGPLTTSIRTRQAMLVDWGSWDRDFNQLTASVCEQLLAIIDGASSHHCVPLQGSGTFAVEAAIGTLVPRDGKVLVLINGAYGQRLAKICKVLGRTYSTFETAEDQPTTAADVDRLLAEDPAITHVALIHCETSTGILNPLPEIAQVIKRHGKRLIIDAMSSFGALPIDAREIPFEALIAASGKCLEGVPGMGFVFAEKSALAAAEGNAHSLAMDLHDQHAYMAKTGQWRFTPPTHVVAALHEALQQYNEEGGLPARHQRYADNCKTLLDGMAAIGLRSFLPAEIQAPIIVTFHAPTDARYQFKDFYERVKAKGFILYPGKLTQVETFRVGCIGVVGADGMQAAVNAVAEVLREMEVLDI
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
2-aminoethylphosphonate--pyruvate transaminase, 2-aminoethylphosphonate aminotransferase, AEP transaminase, AEPT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
Protein: FCGRN_CAMDR
Sequence: MRVPRSQPWGLALLLLLLPGTLRAAESHRSLLYHFTAVSNPASGTPAFSLSGWLGPQQYLSYNNLRAQAEPYGAWVWESQVSWYWEKETTDLRDKEKLFLEALKVFGDRDSYTLQGLLGCELGPDNVSVPMAKYALNGEEFMEFDPKLGIWDGDWPEARTIGIKWMKHPEAVNKEKTFLLYSCPHRLLGHLERGRGNLEWKEPPSMRLKARPGNPGFSVLTCSAFSFYPPELQLRFLRNGLAAGSGEGDVVPNGDGSFYAWSSLTVKSGDEHQYRCWVQHVGPAQPLTVELESPAKSSVPVIGISIGFLLLMTVAAGGALLWRRRKGLPAPWIAFRGDDIGALLPTPGLSKDAES
What is the function of this protein?
Cell surface receptor that transfers passive humoral immunity from the mother to the newborn.  Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk.  IgG in the milk is bound at the apical surface of the intestinal epithelium.  The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids.  Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation.  Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation.  In addition of IgG, regulates homeostasis of the other most abundant circulating protein albumin/ALB.
What are the official names of this protein?
IgG receptor FcRn large subunit p51, FcRn, IgG Fc fragment receptor transporter alpha chain, Neonatal Fc receptor.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endosome membrane.
Protein: HEM3_PARP8
Sequence: MNSETLAPTPPATLVIASRESRLAMWQAEHVRCALHKLYPSCDVKILGMTTRGDQILDRTLSKVGGKGLFVKELENALADGRADLAVHSLKDVPMELPEGFVLSTIMEREDPRDAFVSNQYDSLAALPAGSVVGTSSLRREAMLRARYPELVVKPLRGNLDTRLGKLDRGDYAAIILAAAGLKRLGLGERIRSLLDPADSLPAAGQGALGIEIRAGRDDLAAWLAPLHHEHTAAAVEAERMVSRTLGGSCEVPLAAYATWHDGALHLRGIVATPDGERVLSAQASAPAATTDAALELGREVASQLEAQGALDIVRALSTASGPAASA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: TPIS_CLOPE
Sequence: MRTPIIAGNWKMHYTIDEAVKLVEELKPLVKDAKCEVVVCPTFVCLDAVKKAVEGTNIKVGAQNMHFEEKGAFTGEIAPRMLEAMNIDYVIIGHSERREYFNETDETCNKKVKAAFAHNLTPILCCGETLEQRENGTTNDVIKAQITADLEGLTKEQAEKVVIAYEPIWAIGTGKTATSDQANETIAAIRAMVAEMFGQEVADKVRIQYGGSVKPNTIAEQMAKSDIDGALVGGASLVAADFAQIVNY
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_LYSSC
Sequence: MLDIKRVRDNFAEIKEMLLTRNEDLGNLDDFENLDAKRRELIAKTEELKAERNKVSEQISVMKRNKENADEVIARMRQVGDEIKELDIQLNDVEDRFKDMMMRLPNVPHESVPVGTTEDDNVEEYTWGEIPAFDFEIKAHWDLATDLKIVDFERGAKVTGSRFLFYRGLGARLERALMTFMMDLHAEEHGYEEMLPPVIVNRESLTGTGQLPKFEEDVFKLAETDYFMIPTAEVPVTNFYRDEILTAEALPQGFAAYSACFRSEAGSAGRDTRGLIRQHQFNKVELVRFVKPEESYEQLELLTGHAEKVLQLLGLPYRKLKMCTADLGFTAAKKYDLEVWIPAQNMYREISSCSNFEDFQARRANIRFRREPNAKPEYVHTLNGSGLAIGRTVAAILENYQQADGSVVIPEVLRPYMGGKEVIAPK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INT2_MYCTU
Sequence: MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAWLTDRRREIDRQLWSPASGQEDRPGAPFGEYAEGWLKQRGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVGTPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGASTARRVHKIRPATLDELETITKAMPDPYQAFVLMAAWLAMRYGELTELRRKDIDLHGEVARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKHVNPGRESLLFPSVNDPNRHLAPSALYRMFYKARKAAGRPDLRVHDLRHSGAVLAASTGATLAELMQRLGHSTAGAALRYQHAAKGRDREIAALLSKLAENQEM
What is the function of this protein?
Integrase is necessary for integration of the phage into the host genome by site-specific recombination.  In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome (By similarity).
What are the official names of this protein?
Putative prophage phiRv2 integrase.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: VPK2_VAR67
Sequence: MGVANDSSPEYQWMSPHRLSDTVILGDCLYFNNIMSQLDLHQNWAPSVRLLNYFKNFNRETLLKIEENDYINSSFFQQKDKRFYPINDDFYHISTGGYGIVFKIDNYVVKFVFEATKLYSPMETTAEFTVPKFLYNNLKGDEKKLIVCALAMGLNYKLTFLHTLYKRVLNMLLLLIQTMDGQELSLRYSSKVFLKAFNERKDSIKFVKLLSHFYPAVINSNINVINYFNRMFHFFEHEKRTNYEYERGNIIIFPLALYSADKVDTELAIKLGFKSLVQYIKFIFLQMALLYIKIYELPRCDNFLHADLKPDNILLFDSNEPIIIHLKDKKFVFNERIKSALNDFDFSQVAGIINKKIKNNFKVEHNWYYDFHFFVHTLLKTYPEIEKDIEFSTALEEFIMCTKTDCDKYRLKVSILHPISFLEKFIMRDIFSDWINGRN
What is the function of this protein?
Essential serine-protein kinase involved in the early stage of virion morphogenesis.
What are the official names of this protein?
Serine/threonine-protein kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.
Protein: RU1C2_SORBI
Sequence: MPRYYCDYCDTYLTHDSPSVRKQHNAGYKHKANVRTYYQQFEEQQTQSLIDQRIKEHLGQAAAFQAGAPFNQHMLAFPGAVARPRLPILPTPGMPHGFPQAPLMPGVRPPILPAPGVPGYPGAPPTMPQPGAPPGSMPQPGAPPGSMPQPGAPPGSMPMQMAPLPRPPTLPPPTSGVPGAPIPNSAAPPAIYQANPPAPAGPTSGAPPAPPTAPQPAFSYALPSEGNH
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C-2, U1 snRNP C-2, U1-C-2, U1C-2.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LSAMP_MOUSE
Sequence: MVGRVQPDRKQLPLVLLRLLCLLPTGLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWSLDPRVELEKRHALEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNEGSNVTLVCMANGRPEPVITWRHLTPLGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVKQVKVTVNYPPTITESKSNEATTGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEEHYGNYTCVAANKLGVTNASLVLFSKYAKTEPDSMQVIEFLHIDLKSIRHPLKVNPIQK
What is the function of this protein?
Mediates selective neuronal growth and axon targeting.  Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system.  Essential for normal growth of the hippocampal mossy fiber projection (By similarity).
What are the official names of this protein?
Limbic system-associated membrane protein, LSAMP.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IgLON family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: F16PC_LIGS1
Sequence: MNAYSHNLLKEKYPTKQDVITEIMNLEAILHLPKGTEHFVSDLHGEYTAFDHVLRNGSGSIKQKIQDYFSDRMTEQTMQDFALLIYYPEDELALVKKKLRTENELQQWYLDNISHLLEFLELSGSKYTRSKVRKALNPNFVYITEELLYNDPQEFNKRSYINQLLKNILKLDQADKFIIATCYTIQRLVVDHLHVLGDVYDRGEEPDKIMDRLMNYHSVDMQWGNHDLLWLGAMAGSKLCMLNLLRICARYNNLNIIEDAYGINLRHLSRFAEEQYEDNPQFRPKLTNGDGYRFNGEKLQITQIHQAVAMMQFKLEGQVIARRPELKMDDRDLLNKIDYKKNVINLNGKEYSLQNTCFNTVDPKNPNELTDEENAIVDELLISIQHSTKLKRHLDFMMNKGSMYRTYNGNLLFHGCIPADEEGNFCSLKIGSKEYSGKKLFDFSEKMIRKAYSKPNVKDDFATDFMWYLWQGALSPLFGKKSMTTFERYFIADKACHEEVKNPYYKLRENKDFCIKILQEFGFAGDDTNHIINGHTPVKRGHNAICAEGYMLVIDGGYSKAYQPTTGIAGYTLLYNSYGLQLVSHQPFTSKQDAIRSGKDIVSTVRVVKHELQRKSVADTDIGENIKEKIRVLYNLLRNYD
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: RS12_METCA
Sequence: MTTINQLVRKPRVSKKEKSNVPALEGCPQRRGVCTRVYTTTPKKPNSALRKVARVRLTNGAEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHVVRGSLDTAGVQKRRQGRSKYGAKRPKS
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: HLYC_ECOLX
Sequence: MNINKPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDDYPVAYCSWANLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIRVDPKTHVGKVSEFHGGKIDKQLANKIFKQYHHELITEVKRKSDFNFSLTG
What is the function of this protein?
Protein-lysine myristoyltransferase that catalyzes myristoylation of the protoxin (HlyA) at two internal lysine residues, thereby converting it to the active toxin.
What are the official names of this protein?
Protein-lysine myristoyltransferase HlyC, Hemolysin C, Hemolysin-activating lysine-acyltransferase HlyC, Toxin-activating protein C, PHLY152.
What is the protein family that this protein belongs to?
Belongs to the RTX toxin acyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.