PharMolix/UniProtQA huggingface dataset:
Protein: NRM_MOUSE
Sequence: MAPALLLVPAALASFILAFGTGVEFVRFTSLRPLLGGIPESGGPDARHGWLAALQDRSILASLAWDLCLLLLFVVQHSLMATEAVKAWTSRYFGVLQRSLYVACTALALQLVMRYWETTPRGPVLWEARAEPWATWVPLLCFVLHVVSWLLIFSILLVFDYAELMGLKQVYYHVLGLGEPLSLKSPRALRLFSHLRHPVCVELLTVLWVVPTLGTDRLLLALLFTLYLGLAHGLDQQDLRYLRSQLQRKLHLLSRPQDGEAE
What are the official names of this protein?
Nurim, Nuclear envelope membrane protein, Nuclear rim protein.
What is the protein family that this protein belongs to?
Belongs to the nurim family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: APT_XANOR
Sequence: MTDCSRCAGTNASGPNHWSERIRDIVDFPKPGIVFKDITPLLSDGPDFASALDEMAQPWRTTPLDAVLGIEALGFILGAALARELRTGFVPVRKPGKLPGRTLIREYALEYGTDRIEMHEGALPRGARVLIVDDVLATGGTLRAALGLAAQLELEIVGAAVLVELLALQGRQKWADDVPLLATLSF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRS2L_ARATH
Sequence: MENLPPNRGMWNQEYSHGRISQSFRSAKPLLDRKRPIENAPNSSNPLPQRMKESMDTESVSHNINFNSTPLMELSANTPYKRLKPEIESYADGHPCGLRTPPPRFDLDKEIINGFQTDIYADVGSLSEAFVTPLKEPERVTLSNGCSTSSILDDDFDDSILEEIDLICEQSARKAACQTPTTSIYQTPSKDNKSSDPKASLDFRDVEKFEPDSNVKLKLDEETPTIAADPALLNSMPDECSKYMLSLNDRQRDAACSNISTPLMVIAGPGSGKTSTMVGRVLVLLNEGLLPSNILAMTFTKAATSEMRERIGKSAGKKAAKDITISTFHSFSLQLCRMHADKLQRTSEFSVYGHGQQRRAIIEAVRLYEEEKKNGSKTSVPCESGEGLNGAGAGAVCPEYAKDLSKKWQKFVTQGKASGKSPEQCRKMGNEIGAKILGNYNDILKACDALDYHDLISCSVTLLSDFPEVFKECQDTWKAIIVDEFQDTSTMQYKLLRMLGSHNHITIVGDDDQSIFGFNGADSSGFDSFRRDFPNYKEVRLIKNYRSSRHIVEAASSIIKNNTKRCQSKSISSENSQGSKITVKECHNEEAQCAYVIDKIIEITNDGSTPCCSHGDIAILYRRQVSGKVFQNAFRQRKIPFNVHGVAFYRKKVVQVILAMLKTTFSECDDASYRRVFKALLPFEKEEKKRIIEHIEKISTSRKCSFISAASDIFNAKISGTFKRSQLTQGRKVLQTLDMVAKLVDREQSLSAVVTCVANMIPQKYLLEQRAVVDNDGGKLLNEDNDLRSVLQYLMDDVAEFISTHCTTTEEEDAIKEKKGCNQLHSFINYISERETENFRSRRRDNENSVTLTTIHQSKGLEWDIVFIVKANENEIPLLHESNGNASESGTSLEEERRLLYVAMTRARKKLFFLYVTVDSNWQVLQPSRFLKEIPGHLLQGDMSVNDCRKVHENLPNKTEQSVSSFGTDIKHEESKLTDNDVMNIPEDYASEESIAAYALNGNNFLKRFDVEVRSVVSHLFHNWAKKQAFQEPKRLIDKVRFVIGERLAIKKNKHKDVLRALKSSLTSEEAFQYAEHVLRWEQLPADTRAHIVREKQEHFQKLRIENSMGTSEATSKQIAFLHSLGCTVVPTSRLHASRLIEQYKSL
What is the function of this protein?
ATP-dependent 3'- to 5'-DNA helicase that could disrupt recombinogenic DNA intermediates and facilitate single strand annealing.  Unwinds nicked and partial Holliday junctions in vitro.  Anneals two single strands into a dsDNA molecule in vitro.
What are the official names of this protein?
ATP-dependent DNA helicase SRS2-like protein At4g25120, AtSRS2, DNA 3'-5' helicase At4g25120.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS6_SHEB2
Sequence: MLAKRLVPCLDVKDGKVVKGVQFRNHEIVGDIVPLAARYAEEGADELVFYDITASAHERVVDKSWVSRVAEQIDIPFCVAGGIKTISQARELLAFGADKISINSPALTDPSLISRLQDEFGRQCIVIGIDSFFDATSNSYKVKQFTGDEAATKDTQWFTQDWVEEVQKRGCGEIVLNVMNQDGVRGGYDIKQLSLVRAICDVPLIASGGAGTMAHFRDVFIEAKVDAALAASVFHKAIINIGELKAYLAAEGIAIRR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPSS1_METAR
Sequence: MSQDLSLQKFGFIKRDTPRTVNLDPLQTGGLLTPEAREALLEWGDGYSVCDYCGGMLDQIKTPPIFDFVHKSLPSFIGMDHARVTNGARESKFAIMHAMTSPGDWIVMDGNAHYSSIVAAQRARLNVKLVPKTPAPDYKITPEAYAAAIEEVKQQSGKPPALALLTYPDGSYGNLADAKAITNLAHDFGVPIIINGAYAIGRMPFKGKDLGADFVAGSGHKSMAASGPVGVLGVNEQYAAKVLQKSPTHKNKEIEFLGCTARGATIMTMIASFPAVVERTKPESWEKEVSNARWFSEQMESIGMKQLGDKPHNHDLMFFEGTVFYDISQKTDRYFLYRELKEKSIHGIKPGLTKNFKLSTLGVGREKLGFVMDTLKDIIKKYDG
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase 1, Sep-tRNA:Cys-tRNA synthase 1, SepCysS 1.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: GPDL7_ARATH
Sequence: MLRFIIFFSLFIHLCVAAPQTPAAAAAVPAKKWLTLNGQEPAVVARGGFSGLFPESSASANDLAIGTSSPGLTMLCNLQMTKDGVGLCLSDIILDNATTISSVFPKAQKTYKVNGQDLKGWFVLDYDADTIFNNVTLVQNIFSRPSIFDGQMSVSAVEDVLGTKPPKFWLSVQYDAFYMEHKLSPAEYLRSLQFRGINVISSPEIGFLKSIGMDAGRAKTKLIFEFKDPEAVEPTTNKKYSEIQQNLAAIKAFASGVLVPKDYIWPIDSAKYLKPATTFVADAHKAGLEVYASGFANDLRTSFNYSYDPSAEYLQFVDNGQFSVDGVITDFPPTASQSITCFSHQNGNLPKAGHALVITHNGASGDYPGCTDLAYQKAVDDGADVIDCSVQMSKDGIAFCHDAADLTASTTAMTIFMSRATSVPEIQPTNGIFSFDLTWAEIQSVKPQIENPFTATGFQRNPANKNAGKFITLADFLDFSKAKAVTGVMINIENAAYLASKKGLGVVDAVKSALAKSTLDKQSTQKVLIQSDDSSVLASFEAVPPYTRVLSIDKEIGGAPKPSVDEIKKYAEAVNLLRTSLVTVSQSFTTGKTNVVEEMHKGNISVYVSVLRNEYISVAFDYFSDPTIELATFISGSGVDGVITEFPATATRYLKSPCSDLNKEQPYAILPAEAGGLVVVADKEAQPPASAPNPPLEAKDVIDPPLPPVANLAASNATGGAQSHPPPASGTVANAANLGLSLLAMLALGV
What are the official names of this protein?
Glycerophosphodiester phosphodiesterase GDPDL7, Glycerophosphodiester phosphodiesterase-like 7, ATGDPDL7, Glycerophosphodiesterase-like 6, Protein SHV3-LIKE 5.
What is the protein family that this protein belongs to?
Belongs to the glycerophosphoryl diester phosphodiesterase family.
Protein: NUON_HELMI
Sequence: MNFSLLTTEMLTALLGIGLLAIGLLNRKKDSHRGVAYAAVFGLLGILVVTFFQYGINTNTFHQLWILDDYSVFMKEIFLVAAILVILSAIDYVDGLPRFKTEFYALLVFATLGMMVMASANDLVTLYVGMELMTITFFILVAYILGDGRSSEAGVKYLLLGGASSAVLLYGLSLLYGLTGTTVIPDLLARLTWSPALAIAVVTIIAGFGFKISAVPFHMWSPDIYEGAPTPVTGFLAAASKAAGFAVLVRLFLEGMPLQGGADWLTVIAVLAGVTMVIGNVVAIPQTNIKRMLAYSSVAQAGYLLVGLMSTDAPGVKGILFYAMLYVVANMGAFAVATAVGRAIGSDEIADYAGLSQRQPLLASVMTISLLSLAGIPPLAGFVGKLYLFSAIMDKGVLWPAFLGFVMSMVSVYYYLNVSLYMWRDDPKDDRPIPVSGPMKLTVIFSMVVTVILGIYPGPLAEVATVAAKSLF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IBPA_ECO81
Sequence: MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
What is the function of this protein?
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpA, 16 kDa heat shock protein A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XGPT_ESCF3
Sequence: MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIIIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVIDIPQNTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: K2C8_BOVIN
Sequence: MSIRVTQKSYKVSTSAPRSFSSRSYTSGPGSRISSSAFSRVGSSSSFRGGLGTGMSMAGSYGGAPGLGGITAVTVNQSLLSPLKLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRHLEQQNKVLETKWNLLQQQKTARSNIDNMFESYINNLRRQLETLAQEKLKLEVELGNMQGLVEDFKTKYEDEIQKRTDMENEFVIIKKDVDEAYMNKVELESRLEGLTDEINFYRQLYEEEIREMQSQISDTSVVLEMDNNRNLDLDGIIAEVKAQYEEIANRSRAEAEAMYQIKYEELQTLAGKHGDDLRRTKTEISEMNRNINRLQAEIEGLKGQRASLEAAIADAEQRGEMAVKDAQAKLAELEAALRNAKQDMARQLREYQELMNVKLALDVEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLTSSYGTPGFNYSLSPGSFSRTSSKPVVVKKIETRDGKLVSESSDVLSK
What is the function of this protein?
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
What are the official names of this protein?
Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Cytokeratin-A, Keratin-8, K8, Type-II keratin Kb8.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.
Protein: HEM1_PARUW
Sequence: MRIGVIGINHKLADLKLRDALAKACQKRFGANQSVHDQHHFILLSTCNRTEVYFSSHDLTATHSYLLSILRQDVKEDFDHKLYSFFGMDCFSHLTRVTSGLDSAIVAETEIQGQVKNAYNLATTFLCLPKELHFLFQKSMGIAKRIRSELHLGRGLPNLEHAILQTGKYFFRNTQQPKILFVGASEINRKILHFLKSKQYSDMTICNRSEIRSKELAILYGLHLLPWCQLDSWHQYDWIIFGTKSSEYLIKPEKNFIPADNDKLIMDLCVPRNVEPKLGQNAKITLLNIDQINRLLKIRHRGMTQALIEAENRVNLATYEHTNRYRQKEDSKITIFAASA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HNDD_SOLFR
Sequence: MSMLTITIDGKTTSVPEGSTILDAAKTLDIDIPTLCYLNLEALSINNKAASCRVCVVEVEGRRNLAPSCATPVTDNMVVKTNSLRVLNARRTVLELLLSDHPKDCLVCAKSGECELQTLAERFGIRESPYDGGEMSHYRKDISASIIRDMDKCIMCRRCETMCNTVQTCGVLSGVNRGFTAVVAPAFEMNLADTVCTNCGQCVAVCPTGALVEHEYIWEVVEALANPDKVVIVQTAPAVRAALGEDLGVAPGTSVTGKMAAALRRLGFDHVFDTDFAADLTIMEEGSEFLDRLGKHLAGDTNVKLPILTSCCPGWVKFFEHQFPDMLDVPSTAKSPQQMFGAIAKTYYADLLGIPREKLVVVSVMPCLAKKYECARPEFSVNGNPDVDIVITTRELAKLVKRMNIDFAGLPDEDFDAPLGASTGAAPIFGVTGGVIEAALRTAYELATGETLKKVDFEDVRGMDGVKKAKVKVGDNELVIGVAHGLGNARELLKPCGAGETFHAIEVMACPGGCIGGGGQPYHHGDVELLKKRTQVLYAEDAGKPLRKSHENPYIIELYEKFLGKPLSERSHQLLHTHYFKRQRL
What is the function of this protein?
Catalyzes the reduction of NADP in the presence of molecular H(2) to yield NADPH.
What are the official names of this protein?
NADP-reducing hydrogenase subunit HndD, Hydrogen dehydrogenase (NADP(+)).
Protein: RECF_STRMK
Sequence: MLIRRLALHQLRRFSAVDLSPQPGLNLLTGDNGAGKTSVLEALHLMAYGRSFRGRVRDGLVRQGQEALEIFVEWDEQRADHPPHRRKAGLRHSGQDWKGRLDGEDVAQLGNLCAALAVVTFEPGSHALVSGGGEPRRRFLDWGLFHVEPDFLSLWRRYSRALKQRNALLKQGGPSRMLDTWDHELAEAGEPLTSRRQHYLERLQQRTVALAASLAPQLGIQGLELSPGWRRHELPLADALLLARERDRQAGYTSVGPHRADWSVDFHSIPGRDALSRGQAKLTALACLLAQAEDYAEQRGEWPVIALDDLASELDRTHQARVLERLLNGPAQIFITATETPAALLDLTHIARFHVEHAQIVAVP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_LISMH
Sequence: MAKRDYYEVLGISKSASADEIKKAYRKLSKQYHPDINKEAGADEKFKEISEAYEALSDPQKRAQYDQYGHVDPNQGFGGGAGGGFGGGGFSGFEDIFDTFFGGGGRQQDPNAPRQGSDLQYTMRLKFKEAIFGKDAEIEIPREENCDTCHGSGAKPGTTPEKCSHCGGKGSINVEQNTPFGRVVNKRTCQYCNGTGKEIKEKCPTCHGKGRVTKTKKIKVKVPAGVNDGQQMRVSGEGEAGINGGPNGDLYVVFVVIPDEFFEREADDIYVEVPITFVQATLGDEIDVPTVHGKVRLKIPSGTQTGTTFRLRGKGVPHLRGNGTGDQHVIVKVIVPKKLDDKQKEILREFASTTGDKVDEQTSGFFDKMKRAFKGD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MET3_EMENI
Sequence: MANTPHGGVLKDLIARDAPRHDQLEAEAATLPSIVLTERQLCDLELIMNGGFSPLEGFMNQKDYDGVVAESRLADGNLFSMPITLDASKAVIEQAGLKPGSRVTLRDFRDDRNLAILTIDDIYRPDKEKEAKLVFGGDPEHPAIKYLNTKVEEYYIGGKLEAVNKLNHYDYVGLRYTPAELRIHFDKLGWTRVVAFQTRNPMHRAHRELTVRAARARQANVLIHPVVGLTKPGDIDHFTRVRAYQALLPRYPNGMAALALLPLAMRMGGPREAVWHAIIRKNHGATHFIVGRDHAGPGKNSKGQEFYGPYDAQHAVEKYRAELGIEVVEFQQVTYLPDTDEYMPKDEVPAGTKTLDISGTELRNRLRTGAHIPEWFSYPEVVKILRESSPPRALQGFTIFLTGYMNSGKDAIARALQVTLNQQGGRSVTLLLGDTVRHELSSELGFSREDRHTNVQRIAFVAGELTRAGAAVIAAPIAPYEHSRKAAREAVQSTGGSFFLVHVNTPLEYCEATDKRGIYAKARRGEIKGFTGVDDPYEAPTNANLVVDVSKQSVRSIVHEIILMLESEGYFERL
What is the function of this protein?
Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP.  Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the APS kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I82A4
Sequence: QDLPGNDNSTATLCLGHHAVPNGTIVKTITDDQIEVTNATELVQSSSTGKICNNPHKILDGRDCTLIDALLGDPHCDVFQDETWDLFVERSNAFSSCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSSACKRGPASGFFSRLNWLTKSGSTYPVLNVTMPNNDNFDKLYIWGVHHPSTNQEQTNLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGQSGRISIYWTIVKPGDVLVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCVSECITPNGSIPNDKPFQNVNKITYGACPKYVKQNSLKLATGMRNVPEKQTRGLFGAIAGFIENGWEGMIDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRVIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNADVLVALENQHTIDLTDSEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIESIRNGTYDHDIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQRGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: PLPL8_RABIT
Sequence: MSINLTIDICIYLLSNARNLCGKHRSKQLHLVCSPNHCWKIRHVSLQRGLHPHKVRCKWTKSETHSCSKHYYSPSNHGLHIGILKLSTSAPKGLTKVSIRMSRIKSTLNSVSKAVFGSQNEMISRLAQFKPSSRILRKVSDSGWLKQESIKQAIRSLKKYSDKSTEKSPVPEGRNHIIDKEDDIGKQSLFHYTGNITTKFGESFYFLSNHINSYFKRAEKMSQDKENSHFQEKSELEGKKVEEGKSSSLDPGILTSQADKPDPKSSAGTMDKATSPSGTPESLPISTKQSIANFLSRPTEGVQALVGGYIGGLVPKLKYDSKSQAEEQEEPAKSEPAGSKDKTVEEKKHLSLQREKIIARVSIDNRTRALVQALRRTADPKLCITRVEELTFHLLEFPEGKGVAVKERLIPCLLRLRQMKDETLQAAVREILALIGYVDPVKGRGIRILTIDGGGTRGVVALQTLRKLVELTQKPVHQLFDYICGVSTGAILAFMLGLFHLPLDECEELYRKLGSDIFSQNVIVGTVKMSWSHAFYDSQTWEKILKERMGSALMIETARNPMCPKVAAVSTIVNRGSTPKAFVFRNYGHFPGSQSHYLGGCQYKMWQAIRASSAAPGYFAEYALGNDLHQDGGLLLNNPSALAMHECKCLWPDAPLECIVSLGTGRYESDVRNNTTYTSLKTKLSNVINSATDTEEVHIMLDGLLPPDTYFRFNPVMCENIPLDESRNEKLDQLQLEGSKYIERNEHKMKKVAKILSQEKTTLQKINDWIKLKTDMYEGLPFFSKL
What is the function of this protein?
Calcium-independent and membrane-bound phospholipase, that catalyzes the esterolytic cleavage of fatty acids from glycerophospholipids to yield free fatty acids and lysophospholipids, hence regulating membrane physical properties and the release of lipid second messengers and growth factors.  Hydrolyzes phosphatidylethanolamine, phosphatidylcholine and probably phosphatidylinositol with a possible preference for the former.  Has also a broad substrate specificity in terms of fatty acid moieties, hydrolyzing saturated and mono-unsaturated fatty acids at nearly equal rates from either the sn-1 or sn-2 position in diacyl phosphatidylcholine.  However, has a weak activity toward polyunsaturated fatty acids at the sn-2 position, and thereby favors the production of 2-arachidonoyl lysophosphatidylcholine, a key branch point metabolite in eicosanoid signaling.  On the other hand, can produce arachidonic acid from the sn-1 position of diacyl phospholipid and from the sn-2 position of arachidonate-containing plasmalogen substrates.  Therefore, plays an important role in the mobilization of arachidonic acid in response to cellular stimuli and the generation of lipid second messengers.  Can also hydrolyze lysophosphatidylcholine.  In the mitochondrial compartment, catalyzes the hydrolysis and release of oxidized aliphatic chains from cardiolipin and integrates mitochondrial bioenergetics and signaling.  It is essential for maintaining efficient bioenergetic mitochondrial function through tailoring mitochondrial membrane lipid metabolism and composition.
What are the official names of this protein?
Calcium-independent phospholipase A2-gamma, Group VIB calcium-independent phospholipase A2, Intracellular membrane-associated calcium-independent phospholipase A2 gamma, iPLA2-gamma, Patatin-like phospholipase domain-containing protein 8.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein. Peroxisome membrane; Single-pass membrane protein.
Protein: RL7A_METBF
Sequence: MAQLAKFDVPEELTNKALEALELARDTGKIKKGTNEATKAIERGNAKLVLIAEDIEPAEIIAHIAPLSEEKKAPYIFIKNQKELGAASGLGVSCATVAIVDAGKAGEMVQDIAQKLEALK
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVC_SPHAL
Sequence: MIILGLDPSLSCTGWGLIRVEGSRISHIANGQIKTDAKAALPDRLVHLDTALAAVIADHAPKCAAVEEVFVNDNPQSTLKLAHARGVVLLGCARGGLTVTQYAPRLVKKAIVGTGGAAKGQVQAMLGVLLPGTKVAGPDAADALAVAICHANHRRR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CAYP2_MOUSE
Sequence: MVPPLDLGSLVDSDEEDNFSQTARGTVHVHLNPPRSEPALGWVLPCQRPNSQHRLQEVEQDVIPEDLPAPTGKYRLKYQQYASEMKDGYKQYIQRSTEKPKAASRPEATEKVEGASLDDLMTLDRKALLQQGYADSPYGRQSITRKSDVETVAIEKKKQTVAEQMMMDHLSRAVISDPEQDLNTKNQESSRVPPDSERAPLRVRRRTLHETKIRTNSALTENDLSQKVEFDGRVLSRNGRDACRELIGFFFAHDQSLTVYEYRMFGKNRTSVLPFIKKDIYHHQCGRRKGKQYELGDVYTGATLTFLSCDQPSLPKTIKENALLRLRITNIDQVALNSLKAASAEHGEEEAVSPEAHDQLVLQAIQDKLKEQLHKKGARILTGLGRYFQGLDKEGNGLLEKADFQQALKTFHLEVSEQDFESFWLILQGYGHSKNKVDYGEFKRAIFGEMNEYRKSFVRKAFMQLDFNKTGIVSVIDIRKCYCAKKHPRVISGHSTEEEIKSSFLETLKGTCSKCDEVSYGEFEDYYEGLSIGVAGDEDFVNILRIPWRI
What are the official names of this protein?
Calcyphosin-2, Calcyphosine-2.
Protein: TCPZ_SCHPO
Sequence: MLSLLNPKAESIQRAQALQVNISAAIGLQDVLKSNLGPTGTTKMLVDGAGAIKLTKDGKVLLTEMQIQNPTASCIAKAATAQDDATGDGTTSVCLLVGELLKQAELYIREGLHPSLISDGFNLAKNEALTFLDSFKTDFEVDREVLLNVAKTSLSTKISSKVVESLAPAVVDAILTIRRPDEPIDLHMVEIMKMQNRSASDTQLIRGLLLDHGARHPDMPKQVKNAYILILNVSLEYEKSEINSGFFYSTSEQRERLVESERKFVDNKLRKIVELKKEVCERDPTANFVIINQKGIDPLSLDVLAKNGIMALRRAKRRNMERLQLACGGVAQNSVDDLNPEVLGWAGSVYERTLGEEKYTFVEDVKDPKSATILIHGPNTYTIQQIQDATRDGLRAVKNAVEDNCLIVGAGAFEVACAAHLRNKFAAKEVKGKAKMGVYAYADALLIIPKTLAANSSYDTQDAIVALQEEASEGYKVGLDLKTGMPFDPEVEGIYDNYRVIRHMLHSATVIASNLISVDQILRAGRSSLKEGPPQ
What is the function of this protein?
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis.  Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).
What are the official names of this protein?
T-complex protein 1 subunit zeta, TCP-1-zeta, CCT-zeta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_ACIC1
Sequence: MARVKRAVNAQKKRRVILEQASGYRGQRSRLYRKAKEQVLHSMAYSYRDRKARKGDFRRLWIQRINAAARAQGITYNRLIQGLKLAGVDVDRKMLADLAVRDEATFAALVGTARDALSVAPTSS
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: PUR7_PROMT
Sequence: MNHIQGSLIYEGKAKRVFACENPNRVLIEFKNDATAFNAKKRSEIDGKGRLNCKISAALFKLLELNGIPTHFLELQSETFMIANKINVIPLEVVIRNIATGSLCRETPINQGTILNPPLLDYYYKDDELGDPILTERRLKLLDLISTSQIEKVETITKNVNKILKEYFDDLDLLLVDFKLEFGFNSLGEIVIADEISPDNCRFWDKTNSDPKERILDKDRFRQDLGGVIDAYEEILKRIERDSSNSS
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.