PharMolix/UniProtQA huggingface dataset:
Protein: ATG1_ASHGO
Sequence: MNNVKSGGRPVAIVAERYVVEKEIGRGSFAVVYKGHLADSSAGNVAIKAVSRSKLRNKKLLENLEIEIAILKKIKHPHIVGLLECERTGTDFYLMMEYCALGDLTFFIKKRRSLMDKHPLVRTLFEKYPPPSEHHNGLNRVLVVNYLQQLSSALKFLRSKNLVHRDIKPQNLLLSTPLVDYNDPAEFHARGFVGIYNLPILKIADFGFARFLPNTSLAETLCGSPLYMAPEILNYQKYNAKADLWSVGTVLYEMCCGKPPFKASNHLELFQKIKKANDVIQFPKHAALESAMVDLICGLLTFEPAKRMGFTEFFSNGLVNEDLSPYEVESEPDLETKSKNVAESNMFISEYLPTAERNKRASPIRLGDSCTLRGPCESPQGADPYPQDNTQSDQHEHLHADYSFQVEMGQDGQQADGEEKRKLYNNQEERSNEERQFGQVSNGRNQEDQLLLHQGRGQIPCEQNRQALQSHSHVAAKQIPDKDSKSSVSCQKHAASAPTKNDHRTTRLKEKTKCSYSDLLLEKEYVVVEKKSVEVNALADEFAQAGSGAPAIRLPDQHHNDASQALQMARHSSTSVSAANTAKQTLLRRNSRTLSSSGASTSRRPSLVDRRLSITSLGATNALSKALGMASLRLFGNSHQQSSNGSSTFKQNPNVTSLLSPQTFQDMTENAVLSADHQWDNSRQADVLHDDSIMKALENLTAKVYAIYSFAEVKFSQIIPLPPSSTQDPYTHKRMSNGSCAIDDEEDDIEHSPGAETYRKNSSGANANTGNYNFSLDTIHEMNLNDLPPNDLYILCTEAIVLYMKSLSLLAYAMHLTSKWWHESADKICPLKLNLLVQWIRERFNECLEKAEFLRMKTQSIQLHNGNQLSASTMVSEPVFVEKLIYDRALDISKTAAKMEMQGEYLEGCEVAYSTSLWMLEALLDDVSDEDNYNDDNLGHTGVLDKSDKEVIKRYIDSIANRLKALRRKLSR
What is the function of this protein?
Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes.  Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Also involved in endoplasmic reticulum-specific autophagic process, in selective removal of ER-associated degradation (ERAD) substrates.  Plays a key role in ATG9 and ATG23 cycling through the pre-autophagosomal structure and is necessary to promote ATG18 binding to ATG9 through phosphorylation of ATG9.  Catalyzes phosphorylation of ATG4, decreasing the interaction between ATG4 and ATG8 and impairing deconjugation of PE-conjugated forms of ATG8.
What are the official names of this protein?
Serine/threonine-protein kinase ATG1, Autophagy-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: ARLY_CROS8
Sequence: MALWGGRFTQAADGRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLTAQEQSQLEGALNTLLEEVLENPHAILESDAEDIHSWVEGKLIDKVGPLGKKLHTGRSRNDQVATDLKLWCKTQVHALLSATRQLQQALVVTAEENQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLKDTLKRLDVSPLGSGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDAAISMVHLSRFAEDLIFFNSGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLALGDLQKFSPVISDDVYPVLSLQSCLDKRAAQGGVSPVQVAQAISAAKARLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_ECOSE
Sequence: MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAMVGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: HSCB_BURP1
Sequence: MVSLKDSHFDLFHLPARFALDEPTLDAAYRAVQSQVHPDRFAAAGDAQKRIAMQWATRANEAYQTLRDPLKRATYLLHLRGVDVGAENNTAMEPAFLMQQMEWRERIEDAAGAKNVDALDALLAELRDERRARLAKLGALLDSGSDQGAAEAVRQLMFVERVSAEIGAQIERLEH
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: Y1993_PSEAE
Sequence: MSVDIRPTPPAQDSARQNVTLQIVSVVMFTFIGYLTIGIPLAVLPGYVHDDLGYGSVLAGLVISLQYLATLLARPYAGRVIDGLGPKRAVLYGMAGSAASGLFMLLSVAIQGWPALSLASLLVGRLVLGAAESLVGSAAIGWGIGRVGAPHTAKVISWNGIASYGAIALGAPLGVLLVQWLGLWSMGASIVLLGALGFALAWPKLPAPLVHGERLPFHHVLGRVTPHGMGLALGAIGFGTIATFITLYYASRGWANAVLCLSAFGGCFIGARLLFANSINRLGGFRVAIICLGVESLGLLLLWSAPNPWVGLAGAALTGFGFSLVFPAFGVEAVNLVPASNRGAALGAYSLFVDLSLGITGPLVGFVANLFGFRSMFLFACLASLGGLALAVALHRRSRRPG
What are the official names of this protein?
Uncharacterized MFS-type transporter PA1993.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. YhhS family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRHO_STAAR
Sequence: MNYQVLLYYKYTTIDDPEQFAQDHLAFCKAHHLKGRILVSTEGINGTLSGTKEETEQYMAHMHADERFKDMVFKIDEAEGHAFKKMHVRPRKEIVALDLEEDVDPRHTTGQYLSPVEFRKALEDDDTVIIDARNDYEFDLGHFRGAIRPNITRFRDLPDWIKENKALFADKKVVTYCTGGIRCEKFSGWLLKEGFEDVAQLHGGIATYGKDPETKGQYWDGKMYVFDDRISVDINQVEKTIIGKDWFDGKPCERYINCANPECNKQILVSEENEAKYLGACSYDCAKHERNRYVQANNISGNEWQQRLTNFDDLHQHA
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: DEOC_MYCMM
Sequence: MPGQPTRDQVAALVDHTLLKPEATAADVVALVAEAADLGVYAVCVSPSMVPAAVSAGGVRVATVAGFPSGKHASAIKAHEAALAVACGAVEVDMVIDVGAALAGHLDAVRSDIEAVRCATSGAVLKVIVESAALLGLADESTLIGVCRVAEDAGADFVKTSTGFHPAGGASTRAVEVMASAVGGRLGVKASGGIRTATDAVAMLSAGATRLGLSGTRAVLEGLGQN
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUDC_RAOTE
Sequence: MQKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATATAVAAEINQAGGRAVAIKVDVSRRDQVFAAVEQARKALGGFNVIVNNAGIAPSTPIESITEEIVDRVYNINVKGVIWGMQAAVEAFKKEGHGGKIVNACSQAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGFCPGIVKTPMWAEIDRQCRKRRANRWATARLNLPNASPLAACRSLKTSPPACRSSPARIPTI
What is the function of this protein?
Catalyzes the irreversible reduction of 2,3-butanediol to (S)-acetoin in the presence of NADH.
What are the official names of this protein?
Diacetyl reductase [(S)-acetoin forming], Acetoin(diacetyl) reductase, AR, Meso-2,3-butanediol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SYS_STAAE
Sequence: MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISATEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILCRIPNLISDDVPQGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSGARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDLFKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLIRLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKTYDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRTFAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPX_LACPL
Sequence: MVILYTAPSCTSCRKAKAWLQTHDIDFQEHNLFTEPLSIEKIKQILQLTESGTEEIISTRSKAFQQLNVDINDLSLNELFDMITHDPSLLRRPIMLDEKRLQVGYNEDEIRRFLPRKIRTLELLRAQQLANM
What is the function of this protein?
Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes.  Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP).  This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator.
What are the official names of this protein?
Global transcriptional regulator Spx.
What is the protein family that this protein belongs to?
Belongs to the ArsC family. Spx subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_SALA4
Sequence: MKPDIHPVYRTVVFHDTSANEYVKVGSTIKTEREIELDGVTYPYVTIDVSSKSHPFYTGRQKTFDSESSAARFQKRFGHFIGAKRG
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: RRF_SHEB5
Sequence: MIENIKKDAQERMGKCVDATKNQMAKVRTGRAHPSLLDSIQVSYYGTMTPLNQVANVGVEDSRTLSVTVFDRSAIQAVEKAIMSSDLGLNPMSAGATLRIPLPALTEERRKDFIKVVRNEAENGRIAIRNVRRDAISEVKKLEKAKACTEDDVRRSEEEVQKFTDAHIKKIDEILAAKEIELMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_HALOH
Sequence: MFKFGDEKGQLKCSFCGKSQEQVRKLVAGPGVYICDECIELCNEIIEEELNDDVEFNLNNIPKPREIKKILDQYVVGQERAKKSLSVAVYNHYKRVNSDMKIDDVELQKSNILMVGPTGCGKTLLAQTLARILDVPFAITDATSLTEAGYVGEDVENILLKLIQAADYDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFIAGGAFDGLDKIIKSRIDNKVMGFGADIKSKTEENVGETLKYILPEDLLRYGLIPEFIGRLPVIVTLNELVEEDLVKILTEPRNALVKQYKKFFEMDNVELEFTPEALTAIAQKALERNTGARGLRAVVEEAILDIMYDLPSEPGIAKCVITPEVIKNHKNPELIRVKDKEETA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: SYR_BACSU
Sequence: MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGDYSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLIPSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDVSREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRFVNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALREKGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEVGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLE_STAAE
Sequence: MNKNIIIKSIAALTILTSVTGVGTTVVEGIQQTAKAEHNVKLIKNTNVAPYNGVVSIGSGTGFIVGKNTIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYKVKKIVRYSGQEDIAILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYINKFQMYESTGKVLSVKGNMIITDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKSTKGYGVYFSPEIKKFIADNTDK
What are the official names of this protein?
Serine protease SplE.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL30_MARMM
Sequence: MAKKTIRVRQTGSAIRRPKDQRATLVGLGLNKIGRERELEDTPSVRGMIAKVSHMVEIVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RL10E_METAC
Sequence: MVRKPGSMYRNVRQRSFTRRKYMGGVPGSQVIHYDMGDKANTSFPVKISLIVEEKCQIRHTALEAARITANRHLVADTGKMGFYMKLRVYPHEVIRENKQATGAGADRVSSGMRRAFGKNVGTAARVKPMQKIFTVAVEKQNFKAAKEALWHAGQKLPTPCRIVVDEGAELVQ
What are the official names of this protein?
50S ribosomal protein L10e.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: UBC21_CAEEL
Sequence: MSVSKLNKMQFSDKMSNLALARVTRKCKEVANASDITEAGIHVEIKENNLMDIKGFIKGPEGTPYAGGTFEIKVDIPEHYPFEPPKAKFVTRIWHPNISSQTGTICLDILKDKWTASLTLRTVLLSLQAMLCSPEPSDPQDAVVAKQFINNYPMFTATAVYWTSYFANSKKDVEPDFNRKVGRLIEMGIRETEAIVYLSCNNWKLEQALQFIFD
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.
What are the official names of this protein?
Probable ubiquitin-conjugating enzyme E2 21, E2 ubiquitin-conjugating enzyme 21, Ubiquitin carrier protein 21, Ubiquitin-protein ligase 21.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: RLMKL_VIBC3
Sequence: MNQYLAVTSNGLENLLVEELTQLGINDAKPVQAGVKFKATNEQIYRCCLWSRLASRFVRIVAEFKCQNDLDLYLSTTSVNWVNYFHSSKKLVVDFNGTNREIRNSQYGAMKVKDAIVDCFTKKNLPRPSISKDLADLHIHVRLHKENALLGIDMVGSGLHARGYRTEAGKAPLRETLAAAIILRSGWDASKPLLDPMCGSGTLLIEAAMMAANIAPGLQRKKWGFEALEDFEPELWASVKSEASVQGKRGVKKVETHFYGVDNDNRVLQTAKDNARRAGVEELISFTLGDAAKVKRPENFAEGIVICNPPYGERLGTHPGLIALYTAFGAQLKAEFGGCHASIFSSSDELLSCLRMRADKQFKLNNGALPCHQKNYTIAMREQNSVSNEGTQEILIAPDFANRLKKNFNKIGKWAKREGLDCFRLYDADLPEYNVAIDVYQDHLMIQEYAAPKDIPEEKAKRRLTDIIRAAIQVLDVDANNVVLKVRERQKGTSQYEKLGQQAQTMQITEYGVKLIVNLYDYLDTGLFLDHKITRRRLGQMAQGKDFLNLFAYTGSATVHAACGGAKSTTTVDMSKTYLEWAKENMQLNGQVGRQHQYVQADCLQWLANAQSQYDLIFIDPPTFSNSKRMEQTFDVQRDHVTLMTNLKRLLRPEGTIVFSNNKRHFKMDMEALHALGLNAQNISHQTLPLDFERNKQIHNCWLITHQS
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METE_SHIFL
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLTVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPPRHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALSHNVKPVLLGPVTYLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDNVVELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: IDE_DICDI
Sequence: MVANEQQQQQQEEERKEVKLIQSPNDNNKYRYVKLKNGLEVVLVSDETTDQSSCCLSINIGSLCNPREIEGLAHFLEHMLFLGTEKFPVEKEFVNFIYLNGGSYNGTTSPNKTNYYFTVNQESFEEALDRFSSFFISPLMNEDAVNRELNAVDSEHNNNMQKDFWRMDRIVNDQFEGHPMSMFFTGDSSTLKRDDIREKVVEFYQRYYSANLMKVCIFGRESLDQLEEYANKYFLPIVNKDVKVPKLPPLAITSKSIMIEAEPTQDMDLLKFVFPIPDEKLCFSKNYKNASASILSHILGHECQGSLFSVLFNKDYAFSLSISSNSFYENMNKIEIQIHLTKTGLENVDEVIALLFQSFEFDTPEYFFTEKKLLSEINWKSFQKSAPASTTQAITSNLFRVERPEETLKYNNFLEQFAPEKIKEIQSYLRPDNMICLFYSSTKFKGKTTEIEPHYKIKFNKRYIEQSDFDKWKSFPKNTNLFLPKENPFLPIDTTIKAPQDHSIHIPKEVYNNNGVKVYHSLDHRFNSPKARVNIRFELTSYGNNQSMVMWNLLKKSLKEVLNEKILYYLSVLDFSMKLQILTTHVELQCYCFNDIIFTALGKVFDFLMNLDLNDMQFKRIKEKVAKRFLSSHYLSPYQISMRHLSLHNFNCNSMLLDKQEYLKKVTKSEFLNYFKSLFSYINFSAMVVGNASIEDACAFGEKLNSFSNRNSACPGEVFKLARVNLPSNTITHQREFLYDTNQTNCSSSISFLIGQFNRKTYATTLVICSILGSAYFEELRTKKQFGYVVNCAQDCTGNAISMRCIVQSHTKTPEEIFDATMEFFVGFEKTLDYFKTSPSDFKDLIENCQKQNTVKQQSNSAQSSLYWSFFTFCGDFEFEKKKYEDIGKITFDDVKQYYLDHLSPNTANLRIFAAHCYPQSYQIPDEVKPFGNVKVNLLRKYEHDNFKENHGYLSSKVNLQK
What are the official names of this protein?
Insulin-degrading enzyme homolog, Insulin protease homolog, Insulinase homolog, Insulysin homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2C_GLOC7
Sequence: MDFSSFVASQLNAGTIWPEGIIIITLMVILIGDLIVGRSSKTWLPYVAIAGLLAAVVALYFEWDNPNTLSFLGAFNGDNLSIVFRAIVALSTTVTILMSVRYVEQSGTSLAEFIAIMLTATLGGMFLSGANELVMIFISLEMLSISSYLMTGYMKRDSRSNEAALKYLLIGASSSAIFLYGVSLLYGLSGGETTLDAIAAKITNVNGGQSLGLAIALVFVIAGIAFKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAGFALAIRLLVTAFALVSEQWHFIFTALAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFVMIGLTANSDAGYSSMIFYLLIYLFMNLGAFICIILFALRTGTDQISEYSGLYQKDPLLTLGLSICLLSLGGIPPLAGFFGKIYLFWAGWQSGLYGLVLLGLVTSVISIYYYIRVVKMMVVKEPQDMSESVKNYPEIRWNLPGMRPLQVGLVLSVIATSLAGILSNPLFNLATDSVTSTPILQSAVISTQISQADK
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2, NAD(P)H dehydrogenase subunit 2, NADH-plastoquinone oxidoreductase subunit 2, NDH-1, subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: Y2122_ARCFU
Sequence: MPIAAATDFALNAILRPISDIFVLIYGLLEPINAHLIPEHTNFIYGQLSLLLWGTKFLATILGVTANNATAMANFTDVLHTLSENSYHFFGTVEGESGMAYIAKHSYIELSQNQQLSEDMAVKFARAVNSTIIYFVKVFEYL
What are the official names of this protein?
Uncharacterized protein AF_2122.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CL076_HUMAN
Sequence: MFQNLQGTFEKEIGKIIPFTIAFKRAEAVEPDGCVQSWRCCLPCDLGQASRFIHTTVCSAIRWRSCKGERNFAERHILPAELEEQSNHAGMGPILPAMPSVDGNHFQHPAGDCHPYGILCLQAHSASVTARQVLQ
What are the official names of this protein?
Uncharacterized protein C12orf76.
Protein: TATB_CHRSD
Sequence: MFDMGFLELMLIGVVALLVLGPERLPTAARTVGLWVGKIKRTVSGMQREISAQLEAEELRQKLNEQQRKLDAGLGKVRDEVERHGDAPSSRGGQPPPSRTTPTAARSADDTDETPPSTAASRETPEPPAAPSAKDSNAP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: SYK_YERPY
Sequence: MSEQKPQVAEQAQELNSELQARREKLAVLRGKGIAFPNDFRRENLSDQLHAEFDSKENEELEALNIDVTVAGRMMTRRIMGKASFVTLQDVGGRIQLYVSRDDLPEGVYNEEFKKWDLGDILGARGKLFKTKTGELSIHCSELRLLTKALRPLPDKFHGLADQETRYRQRYLDLIANDESRHTFKVRSQVMSGIRSFMVEKGFMEVETPMMQVIPGGASARPFVTHHNALDIDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGVSPRHNPEFTMMELYMAYADYKDLIVLTEELFRTLTETILGSSVVQYGEQTFDFGKPFAKLTMKEAICKYRPETNVADLDDMDKAVAIAESLGIKVEKSWGLGRIQCEIFEETAESHLIQPTFITEYPAEVSPLARRNDDNPFITDRFEFFIGGREIGNGFSELNDAEDQAQRFADQVSAKEAGDDEAMFYDEDYITALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSP90_SCHPO
Sequence: MSNTETFKFEAEISQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQSLSDPHALDAEKDLFIRITPDKENKILSIRDTGIGMTKNDLINNLGVIAKSGTKQFMEAAASGADISMIGQFGVGFYSAYLVADKVQVVSKHNDDEQYIWESSAGGSFTVTLDTDGPRLLRGTEIRLFMKEDQLQYLEEKTIKDTVKKHSEFISYPIQLVVTREVEKEVPEEEETEEVKNEEDDKAPKIEEVDDESEKKEKKTKKVKETTTETEELNKTKPIWTRNPSEVTKEEYASFYKSLTNDWEDHLAVKHFSVEGQLEFRAILFVPRRAPMDLFEAKRKKNNIKLYVRRVFITDDCEELIPEWLGFIKGVVDSEDLPLNLSREMLQQNKIMKVIRKNLVRRCLDMFNEIAEDKENFKTFYDAFSKNLKLGIHEDAANRPALAKLLRYNSLNSPDDLISLEDYITKMPEHQKNIYFITGESKQAVENSPFLEIFRAKKFDVLFMVDPIDEYAVTQLKEFEGKKLVNITKDGLELEETDEEKAAREKLEKEYEEFAKQLKTILGDKVEKVVVSNKIVGSPCLLTTGQYGWSANMERIMKAQALRDTSMSAYMSSRKTFEINPKSPIIAELKKKVEENGAEDRSVKDLATILYETALLSSGFTLDDPSAYAQRINRLISLGLSIDEEEEAPIEEISTESVAAENNAESKMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).  Interacts with the wee1 protein kinase; which requires swo1 for its activation.
What are the official names of this protein?
Heat shock protein 90 homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECTC_ALIFM
Sequence: MIVRTLDECRDSERRVASETWESVRMLLKNDNMGFSFHITTIYQDTETHIHYKNHLESVYCMSGEGEIEVIGGETYPIKPGTLYILDKHDEHYLRAYKDKEMVMACVFNPPITGTEVHDENGVYPVLD
What is the function of this protein?
Catalyzes the circularization of gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant.
What are the official names of this protein?
L-ectoine synthase, N-acetyldiaminobutyrate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the ectoine synthase family.