PharMolix/UniProtQA huggingface dataset:
Protein: UTP11_LEIMA
Sequence: MTKGKGRNPGASGLDKHLKRKTHLERSQPKSRQHLGQLEKHKDHVLRAKKRKVKVRRLQEIKRAAAQRNPDEFNIGMTKAVMDVANGRMRQRRVRLVESDRKKDMQTTIEHNRRNVQYLEFKAQADQQRATELLNEEAAAALTSTAPQNKHIVFVNSEEEFRSFNPLKHFDVTPEMMRQHPAVRGRIRVLEKTVMPEEILMSGGHQIKSAAQKRKERREVQEKMRRSGADATPETRAAFVERLRAKKELKQYQFTDLLEEVKRESEATASSSKGAPGDDGEQEEAAAQDEVTRLLEWRREQERQAAIATARHVREVGQRIQRSKSLSALAKSIRKQSQGIKRQMEQRRESRFKPGATRRAR
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
Probable U3 small nucleolar RNA-associated protein 11, U3 snoRNA-associated protein 11.
What is the protein family that this protein belongs to?
Belongs to the UTP11 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ISPG_CAMC1
Sequence: MQRYPTKQIKIRDVLIGGDAPISVQSMTFSKTKDVKGTLEQIQRLYFAGCDIVRCAVFDKEDASALKQIVAGSPIPVVADIHFNHTYALIVSEFVDAIRINPGNIGSAKNIKAVVDACKQRNLPIRIGVNSGSLEKRFEDRYGRTVEAMVESALYNIKLLEDFDFTDIKISLKSSDVERTMQAYRALRPKTNYPFHLGVTEAGTAFHATIKSAIALGGLLLEGIGDTMRVSITGELEEEIKVAKAILKDSGRQKEGLNIISCPTCGRLQADLMAAVKLVEEKTKDIKEPLNVSVMGCVVNAIGEAKGADVAIAFGKGNGMIMRHGEVVARLPESELVDRFLQEIDDEIKSRG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: SELO_VIBC1
Sequence: MSVWEGVNFTHRFSELPSAFFTYVTPQLLDNTRWVVWNGEFAQQFGLPAAENEELLNVFAGQKEFAPFAPLAMKYAGHQFGVYNPDLGDGRGLLLAEMQHQDGTWFDIHLKGAGLTPYSRMGDGRAVLRSTIREYLCSEAMAGLGIPTTRALGMMDSDTPVYREKTEYGALLIRVAETHIRFGHFEHFFYTNQLAEQKLLADKVIEWHFPECSEAEKPYAAMFESIVEKTAEMIAYWQAYGFAHGVMNTDNMSILGQTFDYGPFGFLDDYDPNYICNHSDYQGRYAFEQQPRIALWNLSALAHSLSPLVQREDLEAALGKFEVRLSQKFSELMRAKLGLHTKVDEDGRLFEAMFELLNQNKADYTRFFRELSNLDVKSPQAVIDLFIDREAASAWVDLYLARCELEVDECGERVSAQTRCEKMRRTNPKYILRNYLAQIAIDKAEEGDFSEVNRLAELLKRPYDEQPEFDDYTKLPPEWGKKMEISCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: CHED_BORBR
Sequence: MPARLDARATRRYFDSAFNSPAVKILPNEYYVTNGEDVMLSTVLGSCVAACIHDPVIGVGGMNHFMLPEGDIHSPASATMRYGAFAMEVLINELLKAGAVRERLEAKVFGGGAVLSAMQLMNIGERNGQFVLNYLKTEGIPVRAQDLGDVHARRINYFPRDGRVMVRKMAPHHQKAEALIAQREAAAAQTVQAETRAAPRVERFARPGGMRVERFDTPSRRDPVGA
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: ANMK_KLEP3
Sequence: MRSGRFIGVMSGTSLDGIDVVLAAINENIVAQQASLTWPIPHPIKEEILAICQGQSLTLSQLGRLDTRLGRLFADAVLALMRQENLKPTDVIAIGCHGQTVWHEPQGDAPHTLQIGDNNQIAAHTGVTVVGDFRRRDMALGGQGAPLVPAFHHALLAHPIERRMVLNIGGIANVSLLVPGQPVRGYDTGPGNMLLDAWIWRQQGKPYDKDAQWASEGKVLLPLLQDMLSDPWFALPAPKSTGREYFNYGWLEKHLARYSGLRGQDVQATLAELTAVTISEQVLLSGGCERLLVCGGGARNPLLMARLAALLPGTEVSTTDEAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASEATVLGAIFPANPPQNRS
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RS18_BORA1
Sequence: MAFFGKRKEKRKFTQQNPLFKRRKFCRFTAAGVEEIDYKDLDTLRDFVQENGKIIPARLTGTRAIYQRQLDSAIKRARFLALLPYTDNHN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: DNLJ_THEVB
Sequence: MVLKEPPAERIQQLRRLLQRASYAYYALDQPIMEDEVYDQLYRELQELEAAYPEYITPDSPTQRIGEAPVSQFESVSHRIPLYSLENAFTFADMVAWQERWQRYWRTLRQEEPLPPAEYVCELKMDGVALALTYENGLLVRGATRGDGQRGEDVTSNVRTIRPIPLRLALDNPPPVVEVRGEAFLPLERFHQLNQERQAQGEPPFANPRNAAAGTLRQLDPRIVAQRQLDFFAYALHLPEGGSVPLGENQAGEPQSQRQVLYALQHLGFRVNPHHADCPDLEAVKAYYDRWQTARHQLPYLTDGIVVKLNDLKLQQTLGFTQKFPRGSIAWKYEPEQAITDVLAITVQVGRTGALTPVAELAPVQLAGTTVSRATLHNADYIAELDLHIGDKVVIHKAGEIIPEIVRVFPELRPPTARPFTMPTACPECHQPVVRPANEAVSRCGNPRCPAIVRGQIRHWASRDALDIQGLGEKLVQQLVTKELVRTPADLYRLTAAQLLSLERMGQKSADKLLVAIANSKQQPWPRVLYGLGIRHVGSVNAQLLADRFKSVEELATATVADLCGVDGIGEEIAQAVQEWFQDPDHQSLIADLQALGLQLAAALHPAQKALTTEKSLNGKRFVITGTLPTLTREQAKALIQKHGGHVSESVSRQTDYLVVGEKAGSKLRRAQELGIPCINETELIQMCR
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ERA_CLOPS
Sequence: MFKSGFITIVGRPNVGKSTLTNLLMGEKLSIVSNKPQTTRNNIQTILTGDDYQMIFVDTPGIHKPKHKLGEYMVNSATDSIKDVDLVLFLSNPCEEVGRGDKFIIEQLKNQKAPVIFVLNKVDESSPEKVAKTLELFSKEYDFAEMIPISAMKAKNTDKLLELMVKYLPEGPKYYPDDMITDVQERFVVAEIVREKALKNLSQEVPHGIAVDVIQMKQDDNGKYNIEVDLICEKASHKGIIIGKNGQTLKKIGSTARYELERFLRAKVNIKIWVKVRKEWRDNTSLLKELGYKKLK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: PANC_PAEAT
Sequence: MTTAAELRAESARLLAAKGGNSQGLVPTMGALHSGHAALARTAVAENDVVVATIFVNPLQFGDAVDLDRYPRTLDADMALLDAEGVDLVFAPSVDEVYPGGQPLVRVTSGPLGEKWEGASRPGHFDGALTVVAKLLHYGLPGGAAADGTTAAYRAYFGQKDAQQLALVKRMVSDLNFPVEIIPVPIVRSEDGLALSSRNRFLSDAERDAALVLSRALRLIESRANAHEPLHLDSAVALVESQPLVELDYFDVVDPATLEPLAENCKETPFRGEGLAIIAAKVGAVRLIDNAPLFS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DSBB_SHEAM
Sequence: MQSLISFAHSRLSWGILALSALALESAALYFQHIMKLDPCVMCIYQRVAVFGLLGAGLFGFMAPANRVIRALGALLWGISAAWGLKLALELVDMQNNPNPFSTCSFLPEFPSWLQLHEWLPSVFMPTGMCTDIPWEFAGVTMGEWMIVAFSVYLLAWLAFIVPMLKKSA
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SURE_ACIBS
Sequence: MNILIANDDGVFAPGIQALADALKPLGRVVVVAPESERSGFSSALTLDRPLRPIQIAEDVWAVNGTPADCVYLSMNGLFDFEFDLVVSGINRGANLGDDVLYSGTVGAAFEGRLMKQPAIAVSLAGPDVRSYDHKDDYAQAAKWVHDFITKGLPALPPRHIFNINIPDVPQLKGTQITYQGRRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPQRIASQIQSDFFAVANGFVSVTPIQMDATNYAVLEDLQASLG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP19A_SHEEP
Sequence: MLLEVLNPRHYNVTSMVSEVVPIASIAILLLTGFLLLVWNYEDTSSIPGPSYFLGIGPLISHCRFLWMGIGSACNYYNKMYGEFMRVWVCGEETLIISKSSSMFHVMKHSHYISRFGSKLGLQFIGMHEKGIIFNNNPALWKAVRPFFTKALSGPGLVRMVTICADSITKHLDRLEEVCNDLGYVDVLTLMRRIMLDTSNILFLGIPLDESAIVVKIQGYFDAWQALLLKPDIFFKISWLCRKYEKSVKDLKDAMEILIEEKRHRISTAEKLEDCIDFATELIFAEKRGELTKENVNQCILEMLIAAPDTMSVSVFFMLFLIAKHPQVEEAMMREIQTVVGERDIRIDDMQKLKVVENFINESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNLGRMHRLEFFPKPNEFTLENFAKNVPYRYFQPFGFGPRACAGKYIAMVMMKVILVTLLRRFHVQTLQGRCVEKMQKKNDLSLHPDETSDRLEMIFIPRNSDKCLEC
What is the function of this protein?
Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
What are the official names of this protein?
Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein.
Protein: NU3C_PLAOC
Sequence: MFLLHEYDIFWAFLIISSVIPILAFLISGVLAPISEGPEKLSSYESGIEPMGDAWLQFRIRYYMFALVFVVFDVETVFLYPWAMSFDVLGVPVFIEALIFVLILIVGSVYAWRKGALEWS
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic, NAD(P)H dehydrogenase subunit 3, NADH-plastoquinone oxidoreductase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SRSF1_MOUSE
Sequence: MSGGGVIRGPAGNNDCRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDGYDYDGYRLRVEFPRSGRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPSGSWQDLKDHMREAGDVCYADVYRDGTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAYIRVKVDGPRSPSYGRSRSRSRSRSRSRSRSNSRSRSYSPRRSRGSPRYSPRHSRSRSRT
What is the function of this protein?
Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing (PubMed:28785060).  Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF.  Can stimulate binding of U1 snRNP to a 5'-splice site-containing pre-mRNA.  Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC.  Binds preferentially to the 5'-CGAGGCG-3' motif in vitro.  Three copies of the octamer constitute a powerful splicing enhancer in vitro, the ASF/SF2 splicing enhancer (ASE) which can specifically activate ASE-dependent splicing (By similarity).  Specifically regulates alternative splicing of cardiac isoforms of CAMK2D, LDB3/CYPHER and TNNT2/CTNT during heart remodeling at the juvenile to adult transition.  The inappropriate accumulation of a neonatal and neuronal isoform of CAMKD2 in the adult heart results in aberrant calcium handling and defective excitation-contraction coupling in cardiomyocytes.  May function as export adapter involved in mRNA nuclear export through the TAP/NXF1 pathway (PubMed:15652482).
What are the official names of this protein?
Serine/arginine-rich splicing factor 1, ASF/SF2, Pre-mRNA-splicing factor SRp30a, Splicing factor, arginine/serine-rich 1.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus speckle. Note=In nuclear speckles. Shuttles between the nucleus and the cytoplasm. Nuclear import is mediated via interaction with TNPO3.
Protein: FOLD_PROMA
Sequence: MTNILDGKKLAKELELRLHEDITEFSPEVGRPPGLAVIRVGDDPASGIYVSNKEKACNRIGLDSFLYHLGTNTSEQEILEVIKALNNDQKVDGILLQLPLPKGLDAEPLLKAIDPEKDVDGLHTLNLGRLLKGEKGPRSCTPAGIMVLLRRNNISLVGKKVVVIGRSILVGKPMALMLQAANATVTVAHSKTINLPEITNQAEVLIVAAGIPQLIGLEHVRSNAVVVDVGIHRIPMEPLKLTGSNYKLCGDVRAEEIYSKIKAITPVPGGVGPMTVAMLMVNTVNRWQYHCGLSSTLSDLLP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: OPSP_ICTPU
Sequence: MASIILINFSETDTLHLGSVNDHIMPRIGYTILSIIMALSSTFGIILNMVVIIVTVRYKQLRQPLNYALVNLAVADLGCPVFGGLLTAVTNAMGYFSLGRVGCVLEGFAVAFFGIAGLCSVAVIAVDRYMVVCRPLGAVMFQTKHALAGVVFSWVWSFIWNTPPLFGWGSYQLEGVMTSCAPNWYRRDPVNVSYILCYFMLCFALPFATIIFSYMHLLHTLWQVAKLQVADSGSTAKVEVQVARMVVIMVMAFLLTWLPYAAFALTVIIDSNIYINPVIGTIPAYLAKSSTVFNPIIYIFMNRQFRDYALPCLLCGKNPWAAKEGRDSDTNTLTTTVSKNTSVSPL
What are the official names of this protein?
Parapinopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRG_ACIF5
Sequence: MSKYIFVTGGVVSSLGKGAAGAALGALLEARGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTADGAETDLDLGHYERFLSTRMGKRNNFTTGLVYQTVIEKERRGDYLGRTVQVIPHVTDEIKRRIRLGAADADVALVEIGGTVGDIESQPFLEAIRQMAVEEERGDTLFMHLTLVPYLASAGEMKTKPTQHSVRELRAIGIQPDVLLCRADRPIPADHRAKIGLFSNLPEKAVISAIDTDSIYRIPLLFHAQGLDDLVVQNLGLHLSAPDLSVWNGIINALEHPEGEVVIALVGKYVGLTESYKSLAEALLHAGLRARRSVRFLYVDAEDVETQGTEILAEADAILVPGGFGGRGTEGKIASIRHARERKVPYLGICLGMQLAVVEFARHRAGLMNANSTELDPQTPAPVITLMTEWSDPEGHKAYREEGGNLGGTMRLGEQECRLEPDSLAIQAYGQERIHERHRHRFEFNNRYREPLAMAGLRYTGFSADSELVEVVELPDHPWFLGCQFHPEFTSNPREGHPLFDAFMRAAIAQRERDGSS
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: NAGB_ECOLI
Sequence: MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEGCVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: RTCA_HALSA
Sequence: MHVLDGSSGGGQLVRTALTCAAVSGESFRMRYVRRARSNPGLQAQHCAAVNAVADICDAATDGVEVGSEAFSFEPEVAAEEADDDEEPTLGGTTSVEVGTAGSIPLVFDSLLPLAGALDEPITATLTGGTDAKWAPPMDYFQHVKLPLLREHGIDATVSVDRRGFYPRGGGEATLTVEPSTPTPITLTERGDREALTAYSVAESSLADDEVAEQQATAAAPDAAHEIAYTDADSAGSAVVLAAEYEHSRAGFAALGERGVSADAVGENAADALAAFESGPGAVDSHLADQLVPVVAVAGGEVRAPEVTTHIETCVDLLAEFDYDIDIEHTDDGAVVLSA
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity).
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ST1B1_HUMAN
Sequence: MLSPKDILRKDLKLVHGYPMTCAFASNWEKIEQFHSRPDDIVIATYPKSGTTWVSEIIDMILNDGDIEKCKRGFITEKVPMLEMTLPGLRTSGIEQLEKNPSPRIVKTHLPTDLLPKSFWENNCKMIYLARNAKDVSVSYYHFDLMNNLQPFPGTWEEYLEKFLTGKVAYGSWFTHVKNWWKKKEEHPILFLYYEDMKENPKEEIKKIIRFLEKNLNDEILDRIIHHTSFEVMKDNPLVNYTHLPTTVMDHSKSPFMRKGTAGDWKNYFTVAQNEKFDAIYETEMSKTALQFRTEI
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3) (PubMed:28084139, PubMed:9443824, PubMed:9463486).  May play a role in gut microbiota-host metabolic interaction.  O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria.  The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system (PubMed:35165440).
What are the official names of this protein?
Sulfotransferase 1B1, ST1B1, Sulfotransferase 1B2, Sulfotransferase family cytosolic 1B member 1, Thyroid hormone sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_ACTSZ
Sequence: MNPIVKQFKYGQHTVTLETGAIARQATAAVMASMDDTTVFVSVVAKKEVKEGQDFFPLTVDYQERSYAAGKIPGGFFKREGRPSEGETLIARLIDRPIRPLFPEGFLNEIQIIATVVSVNPQISPDLVAMIGASAALALSGVPFNGPIGAARVGFINDQFVLNPTMAEQKQSRLDLVVAGTDKAVLMVESEADILTEEQMLAAVVFGHQQQQVVIEAIKELVKEAGKPRWDWVAPEPDTALINQVKVIAESRLGDAYRITEKQVRYEQIDAIKADVIAQITAENEEVSEGKIVDIFTALESQIVRGRIIAGEPRIDGRTVDTVRALDICTGVLPRTHGSAIFTRGETQALAVVTLGTERDAQILDELTGERQDTFLFHYNFPPYSVGETGRVGSPKRREIGHGRLAKRGVAAVMPSISEFPYVVRVVSEITESNGSSSMASVCGASLALMDAGVPVKSAVAGIAMGLVKEEDKFVVLSDILGDEDHLGDMDFKVAGTRTGVTALQMDIKIEGITPEIMQIALNQAKSARMHILGVMEQAIAAPRAEISEYAPRIYTMKIDPKKIKDVIGKGGATIRTLTEETGTSIDIDDDGTVKIAAIDGNAVKEVMARIEEITAEVEAGAVYTGKVTRLADFGAFVAILGNKEGLVHISQIAEERVEKVSDYLQVGQDVQVKVVEIDRQGRIRLTMKDIVSKAENADAQTDIVEE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y772_TREPA
Sequence: MCATLRPMETLGFCMLSPSTLPLRKWGIRLCRAGYRALGALLGTGVLVCCASSTNMTVSNDYPPKELGVLNAYTVDRLRTAISPRDFTFVFDPPIDTVLMQFKFLLDGITLYLERKDRTALREAIEKYLGEYEAQTLTREKSSERAYFGTTTPLMTWGILGSAHNATPTMRFEYQFITDDRPYFIIANRTIPGANGYNCPAVRIALSPAQCSQVMQYLDQGNLDALLEEMAQSFETFDTQQDPKKTPETDKNAAYKGKEKKGKKEERGPRSIMK
What are the official names of this protein?
Uncharacterized protein TP_0772.
Protein: PYLS_METBU
Sequence: MEKQLLDVLVELNGVWLSRSGLLHGIRNFEITTKHIHIETDCGARFTVRNSRSSRSARSLRHNKYRKPCKRCRPADEQIDRFVKKTFKEKRQTVSVFSSPKKHVPKKPKVAVIKSFSISTPSPKEASVSNSIPTPSISVVKDEVKVPEVKYTPSQIERLKTLMSPDDKIPIQDELPEFKVLEKELIQRRRDDLKKMYEEDREDRLGKLERDITEFFVDRGFLEIKSPIMIPFEYIERMGIDKDDHLNKQIFRVDESMCLRPMLAPCLYNYLRKLDKVLPDPIRIFEIGPCYRKESDGSSHLEEFTMVNFCQMGSGCTRENMEALIDEFLEHLGIEYEIEADNCMVYGDTIDIMHGDLELSSAVVGPIPLDREWGVNKPWMGAGFGLERLLKVRHNYTNIRRASRSELYYNGINTNL
What is the function of this protein?
Catalyzes the attachment of pyrrolysine to tRNA(Pyl).  Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
What are the official names of this protein?
Pyrrolysine--tRNA ligase, Pyrrolysine--tRNA(Pyl) ligase, Pyrrolysyl-tRNA synthetase, PylRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_CLONN
Sequence: MNKSTNNLQDLFLNNARINRISVTIFLTNGYKLEGLVKGFDNFTIILDNNGKQMMIYKHAVSTIIPKSPILFTNKEK
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: YHFW_BACSU
Sequence: MANQHFAKEAPETYWKTSTDLPSFPALQEDTECDVTIIGGGITGITTAYELTKRGFRVVLIEANQVLNGTTAHTTAKVTAQHDMIYDEFIRHFGLNHARLYYEANQNAIDYIKGIVDEHQIDCEWIEQDAYLYTANENAVQKIHTEHEAYTKLGIERDLIKDLPIPLGSKLALVMKNQAQFHPLQYLKALLEQIVQKGGRIYEETVALDIKKGERPEVVTKSRHAIKSRFIICCSHFPFYDGGGLYAARMYSDRSYVLAIKPKIEYPEGMYLSIDQPSVALRYTVVNGEKLILFSGVSHKTGQGKAMSTHYETLRQLAESTIGIESIPYYWSTQDLVTIDKIPFIGPMSENEDNILVATGFKKWGMTSSAVAATLLSDLVEKKENPYESIFTPSRFHLNPGLQKVISYNADVAKHLIKGKLEKPDVQFEDISPGEGKAVTINGRRAGAFRDETGCLHLVDTTCTHLGCEVEWNDSEHTWDCPCHGSRFKPSGEVVEGPAIKPLKQIDLD
What are the official names of this protein?
Putative Rieske 2Fe-2S iron-sulfur protein YhfW.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
Protein: DNAK_STRGR
Sequence: MARAVGIDLGTTNSVVSVLEGGEPTVITNAEGARTTPSVVAFAKNGEVLVGEVAKRQAVTNVDRTIRSVKRHMGTDWKIDLDGKSFNPQQMSAFILQKLKRDAESYLGEKVTDAVITVPAYFNDSERQATKEAGEIAGLNVLRIVNEPTAAALAYGLDKDDQTILVFDLGGGTFDVSLLEIGDGVVEVKATNGDNHLGGDDWDQRVVDYLVKQFANGHGVDLSKDKMALQRLREAAEKAKIELSSSTETTINLPYITASAEGPLHLDEKLTRSQFQQLTADLLDRCKTPFHNVIKDAGIQLSEIDHVVLVGGSTRMPAVAELVKELTGGQEANKGVNPDEVVAIGASLQAGVLKGEVKDVLLLDVTPLSLGIETKGGIMTKLIERNTTIPTKRSEIFTTAEDNQPSVQIQVYQGEREIAAYNKKLGMFELTGLPPAPRGVPQIEVAFDIDANGIMHVAAKDLGTGKEQKMTVTGGSSLPKDEVNRMREEAEKYAEEDHARREAAESRNQGEQLVYQTEKFLKDNEDKVPADVKTEVETAVGELKEKLKGEDSAEIRTATEKVRGRLPRIWARRCTANAQAEGAAPGADAPGDAQAKADDDVVDAEIVDDEKDTKGGAA
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.