PharMolix/UniProtQA huggingface dataset:
Protein: SYA_MYCPU
Sequence: MLSSKEIRQKWITFFESKNHLKLESKSLIPVDDPSLLWINSGVATLKDYFSGKKTPPSPRIVNSQKSIRTNDIENVGITARHHTFFEMLGNFSIGDYFKKEALAFAKEFVLDVLKLEKEKLYFTYYHEDLETKQIWLDLGFDPSHLIAGSRKTNFWDVGMGPCGPNTEIFYDRGPKYDPRGVELLKEDIENDRYIEIWNIVFSTFNNDGKNNYSELKLKNIDTGAGFERIVSILQNAPTNYDTDLFLPIIRAIEKLTNKKYVVENYFQNEPVQREINTYFKIIADHMRSVANAIGDGAGVSNVGRDYIIRRLIRRAYRTGIQLGIKDEAFLYKLVPVIKDSLIFDYDTKHVAKVIKDEELLFSKTIDQGKKILEKEFEKSKKIDASIVFKMFDTYGYPVELTKEMAKEKGVEISLEEFEKYRQEHELKSKSKKGDGMKKVINFLANIDKKVDEFVGYDTLETTSKILYLFNSESKLNKLEGQGYFILDKTPFYATSGGQKHDQGYVEQDGKKFKILEVFKDKNWNHVHLVKGEIDSSKELKCVVDAKNRKNLERNHSATHLLFKVLRDQIGPFVVQLGSNNNEKRLTFDFPSQNKPSKEKIKEIEKQVRKIIELSIDRQYSNETIDKAKEMGAIITIEETEYMDPTNVRIVTFKNITSDLCGGTHIPNTKLIENFKIISVENKGTGIFRISAITTEKLVRAFNQEHFDNLIEQQQNIIKKIQKINPSFKYKNQFKSDDLEQRQVEVEESILALQQEFKKALKSQENVEINFENLEFENIANYKVYINLEADKNTIKAQGAQLREKFDDLLIILASVEKNSTILTIASKKYDSNKIFNLLKSEYSLKGGGNAILVQGFTSDKITKDKILKVLNG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSA_MYCBP
Sequence: MSFPYFISPEQAMRERSELARKGIARAKSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTTEPIANALKESYAENASLTDALGIAVAALRAGSADTSGGDQPTLGVASLEVAVLDANRPRRAFRRITGSALQALLVDQESPQSDGESSG
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit alpha, 20S proteasome alpha subunit, Proteasome core protein PrcA.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OPSD_SARDI
Sequence: MNGTEGPFFYIPMVNTTGIVRSPYEYPQYYLVNPAAYAILGAYMFFLIIVGFPVNFMTLYVTLEHKKLRTPLNYILLNLAVADLFMVIGGFTTTMYTSMHGYFVLGRLGCNLEGFFATLGGMISLWSLAVLAIERWVVVCKPISNFRFGENHAIMGVSLTWGMALACTVPPLVGWSRYIPEGMQCSCGIDYYTRAEGFNNESFVLYMFFCHFTIPLTIIFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVIIMVIGFLVCWLPYASVAWFIFTHQGSEFGPLFMTIPAFFAKSSSIYNPMIYICMNKQFRHCMITTLFCGKNPFEGEEEGASSTKTEASSASSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: EAF1_MOUSE
Sequence: MNGTANPLLDREEHCLRLGESFEKRPRASFHTIRYDFKPASIDTSCEGELQVGKGDEVTITLPHIPGSTPPMTVFKGNKRPYQKDCVLIINHDTGEYVLEKLSSSIQVKKTRAEGSSKIQARMEQQPARPPQPSQPPPPPPPMPFRAPTKPPAGPKTSPLKDNPSPEPQLDDIKRELRAEVDIIEQMSSSSGSSSSDSESSSGSDDDSSSSAGEDNGPASPPQPSHQQPYNSRPAVANGTSRPQGSSQLMNTLRNDLQLSESGSDSDD
What is the function of this protein?
Acts as a transcriptional transactivator of ELL and ELL2 elongation activities.
What are the official names of this protein?
ELL-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the EAF family.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, Cajal body.
Protein: YL412_MIMIV
Sequence: MHNYTSDSDEEIKLEFTDNGKSYTKVYHIPYRTNHSNEKKLICFSIINGENCIYGPNCTYAHSLSEQIIEEDKKFIYRIILDENLMGFSSISESNEKGCINESNKNMSDRKIEEIYKKLLNLTHICEKCTSNKCTGGYNCRNGVFDSSLKICKNDLLTGECLNKLVNIKVDEIIVDKLNSNQTESFKSCQSYQGCINGHHLTLRNIIPYYKYVHQKENSRKYQYQSVRYIDIDQLGKLFCNNNVGSNTYCYQNESDDTESSTDEEISSWFRKDEFEFSDSDNTV
What are the official names of this protein?
Uncharacterized protein L412.
Protein: FBK79_ARATH
Sequence: MSTTAKEAPSSLFSLLPNDIVLNILARVPRWYHPILSCVSKNLRFLVSSSELKITRSLLEKDRFYVCFQEHSNSPSLTTYHWFSFTENRRCLVSIPFTSPVEPYFATLTLGPEIYFVGKSRSMWILDSRSGKLRQGPRPLVACDQAAVGLVNDKIYVFGGIDDMNKRYYEGIHAQVFDLKTQTWHVGPNLSVKLACLNRSVVTPSLGRKIYVRGTDRDVTIYDIKDGKCDKIIPADDFSSGDMCVVDNVIYMYYHNVGLMWYESKEKQWSVVHGLEFNGVFNSIAIAEYNGKLAFLWHDRNKREIWCAMINLYGSSKVAIRGRVEWSHRLLSDLPSNYNFKHFTICTDY
What are the official names of this protein?
Putative F-box/kelch-repeat protein At4g02310.
Protein: YCIB_SHIDS
Sequence: MKQFLDFLPLVVFFAFYKIYDIYAATTALIVATAIVLIYSWVRFRKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQRMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLIFTLLSGIYIYRHMPQEDKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DEOC_RHIME
Sequence: MNNISNRRQPPASLAPRDLAALIDISAVQAFHTEADVRELAGIAVAEGFIAAHALPNFVPLLRSLVPSGGLTLVGGPVGFPSGGHSTRTKTAEAVELAENGAQELDMMINVGRIKSGDFGYVRSEIRAIVEAIAPVPLKVILELAHLTDEEIRAASAIVAESGAAFVKTGTGWTPSATTLEKLKLIVETVGGAVEIKASGGIRSLDAIAGMMRLGVTRFGINTQVAVDLVRQCAALPGGRLDIAGKAG
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPB42_BOVIN
Sequence: MGQGLGIKSCDFQAARNNAEHHTNDISSQRLFVRRGQPFTISLHFQAPVHTFLRALKKVALIAQTGKQPSKANGTQATFSVSSLGDRKWWSAMVEERDDQSWTISVTTPADAIIGHYSLLLQISGRKQCLGQFTLLFNPWNREDAVFLGNEAQRKEYLLNQNGLIFLGTADCIQAEPWDFGQLEEDVIDLGLSLLTVDNQVEKWGNPVHVARVLGALLHILKEKSVLPTAKIQTTEERALLNKRRGSAPILRQWVTGHGRPVYEGQAWVLAAVACTVLRGLGIPARVVTTFTSAQGTGGDLLVNEYYNEEGLQNGEDNRGRAWIFQTSTECWMARPDLLEVYDGWQILYPSALKGGEVLEACDLVPVRAVKEGIVWLTPAASDIFASINASCVVWKCGEDGTLELTDSNTKYFGNNISTKNVDCDCHEDITQNYKYPEGSSQEKMVLEKVQKYRMKHKNDGIYPPCCETDDPLHLFLKAPSSLALGKNVEISVNLLNPTDQEKEVQLAIGLQAMYYNGVLAAKLWRKNFVLILSANSAKKISTSLFNSNFEQSLPENSFLRLTAMATHSSLPCFAQQDIAIRRPHLAIEMPETAEQHQTLIALVSIHNPLDVPLEDCVISIFGKGLIHREKSYRVNSVQPRNTLRTQLKFVPMKVGCQRLTVEMDCNMFQNLTNFRTVMVVAPKSPA
What is the function of this protein?
Probably plays an important role in the regulation of erythrocyte shape and mechanical properties.
What are the official names of this protein?
Protein 4.2, P4.2, Erythrocyte membrane protein band 4.2, Erythrocyte protein 4.2.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of erythrocyte membranes.
Protein: MOBA_BACC1
Sequence: MSKWAGIVLAGGMSSRFGEPKALASWQGSTFIEHILKVMTSALQEVVVISHSDIKERVEQFVQVPVIEDIPHYKGDGPLAGIVSGMEYIEADWYAIMPCDAPNVSQEWFTILLEQTSKEYDAVVPIINGRKQPLLAAYHNRVKEKIYALLQEEKRSMGQLLSQCNVKYIAGEDVQANADWFINVNTKEEYVQAQKDLSNE
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_SHIFL
Sequence: MYQPDFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYPTVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: XFBM1_XENBM
Sequence: GWASKIGQTLGKMAKVGLHELIQPK
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Xenoposin precursor fragment BM1, XPF-BM1.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family. Magainin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SPAST_MOUSE
Sequence: MSSPAGRRKKKGSGGASPAPARPPPPAAVPAPAAGPAPAAGSPPKRNPSSFSSPLVVGFALLRLLACHLGLLFAWLCQRFSRALMAAKRSSGTAPAPASPSPPEPGPGGEAESVRVFHKQAFEYISIALRIDEEEKAGQKEQAVEWYKKGIEELEKGIAVIVTGQGEQYERARRLQAKMMTNLVMAKDRLQLLEKLQPVLQFSKSQTDVYNESTNLTCRNGHLQSESGAVPKRKDPLTHASNSLPRSKTVLKSGSAGLSGHHRAPSCSGLSMVSGARPGPGPAATTHKGTPKPNRTNKPSTPTTAVRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQELAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFGDTTV
What is the function of this protein?
Involved in lipid metabolism by regulating the size and distribution of lipid droplets.
What are the official names of this protein?
Spastin.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Spastin subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Endoplasmic reticulum. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Cell projection, axon. Note=Forms an intramembrane hairpin-like structure in the membrane. Localization to the centrosome is independent of microtubules. Localizes to the midbody of dividing cells, and this requires CHMP1B (By similarity). Enriched in the distal axons and branches of postmitotic neurons (By similarity). Evenly distributed along early axons and concentrates in the growth cone of the axons of late stage 3 neurons (PubMed:18234839). Mainly nuclear in interphase cells and becomes associated with the centrosomes, spindle microtubules, midzone and finally the midbody during cell division (By similarity). SUBCELLULAR LOCATION: [Isoform 1]: Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus membrane. Lipid droplet. Cytoplasm, cytoskeleton. Endosome. Note=Forms an intramembrane hairpin- like structure in the membrane. Recruited to nuclear membrane by IST1 during late anaphase. Localizes to endoplasmic reticulum tubular network. SUBCELLULAR LOCATION: [Isoform 2]: Cytoplasm. Endosome. Nucleus membrane. Note=Constitutes the main endosomal form. Recruited to nuclear membrane by IST1 during late anaphase.
Protein: NUOA_BACCR
Sequence: MASVYENSYMIVLIFLLLGILLPVVALTLGRMLRPNKPSAAKATTYESGIEPFHDANIRFHARYYIFALLFVIFDVETLFLYPWAVAYDKLGLFALIEMLIFVVMLLVGLAYAWKKKVLQWL
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YGD4_SCHPO
Sequence: MSELVLITGITGFVASHSAEALLSQGYRVRGTYRFQEKLDGLLKNRPEWEKKVEFVQVPDCRAPNAYVEAAKGVDYVIHAATEVHSNLEPPRKDPHELLHIAIQGCENALIAAAQEPKVKRFVYISSEAALKGPVNYFGDGHVFTEKDWNPKTLREAEESDDELLNYTVCKKLGERAMHAFVARNTPRFQAIALNPPLILGPVFHLQSVDNLNFSTWFFWQLIKGRYEVAPESKFFNYVDVRDLAEAQVKALTAKTDKDRFVISGGAFKNDDIVNVALKYFPQFKDKIAKPNGETSPCNYEVDASLSIKELGLTYRPAEETFKDATESLYKLAGLL
What are the official names of this protein?
Putative uncharacterized oxidoreductase C1773.04.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. Dihydroflavonol-4-reductase subfamily.
Protein: CYNS_AJECG
Sequence: MSNINLTTLDISEHPNLPTSSAVLFKAKADKRLSFEKIASHIGRNEVATAAIFYGQAKASAEDIDKLAEVLGINYGQLEFLLSGFPDRGKSVPFPPKDPLIYRLYEIVQNYGYAYKAVMNEKFGDGIMSAISFSTKVEKETDKDGNDWAVVTWRGKWLPYSRF
What is the function of this protein?
Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.
What are the official names of this protein?
Cyanate hydratase, Cyanase, Cyanate hydrolase, Cyanate lyase.
What is the protein family that this protein belongs to?
Belongs to the cyanase family.
Protein: CTU1_KLULA
Sequence: MFTPPTDPKKSVKVKVSQLCELCHARKAVMKRPKNLQRICKECFFSVFETEIHNTIVSNNLFHRGERIAVGASGGKDSTVLAYVLKLLNDRHDYGVEIVLLSIDEGIVGYRDDSLATVKRNQVQYDLPLEIVSYKDLYNWTMDEIVACAGIRNSCTYCGVFRRQALDRGAAKLGIKHVVTGHNADDMAETVLMNILRGDVARLEKSTSILTQSSGSPIKRSKPFKYSYQKEIVLYAHYKKLDYFSTECSYAPEAFRGTARELMKNLEAIRPSCIIDIIHSGESLKLKPKRAKKAPPPSHMEIRPDGSVSLQNEFIDGNRCERCGYLSSNKICKACMLLEGLEQNRAKIQLEKDSTTEGAAKLSRTLEKLQF
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation.  It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 1, Cytoplasmic tRNA adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP47_CHICK
Sequence: MKEFVSMRLLPEDMFWSCRQSTLAEMKKKFAQVESAAEEPRVLCIIQDTTNSKTVNERVTLNVPASTPLKKLFEDVASKVGYVNGTFDLVWGNGDNVTDMTPIDQNSDKTILDAGFEPGKKNFLHLTDKDGEQPHIMQEESGTTEDSAQDRFIGPLPREGSVGCTNDYVSQSYSYSSVLSKSETGYVGLVNQAMTCYLNSLLQTLFMTPEFRNALYKWEFEESEEDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSEAWQQHDVQELCRVMFDALEQKWKQTEQADLINQLYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRPYGSNQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSIFIDVEDEKSPQTESCTDSGAENEGSCHSDQMSNDFSNDDGVDEGICLESNSAAERIAKVGSEKNSLLYELFSVMVHSGSAAGGHYYACIKSFSDDQWYSFNDQHVSKITQEDIKKTYGGSSGSRGYYSSAFASSTNAYMLIYRLKDPARNAKFLESHEYPDHIKQLVQKERELEEQEKRQREIERNTCKIKLFCMHPTKQIMMENKLEVHKDRTLKEAVGIAYKLMDLEEAVPLDCCRLVKYDEFHDYLERSYEGEEDTPMGLLLGGVKSTYMFDLLLETRRPDQIFQCYKPGEVMVKVHVVDLKTESVAPPISVRAYLNQTVSEFKQLISKATHLPAETMRVVLERCYNDLRLLTVSSKTLKAEGFFRSNKVFIESSESLDRHVAYTDSHLWKLLDRHANTIRLYVSLPEQSPGSQFRRSIYQKPSGDLGNLDEACERVKGPAGNMKSVEAILEESTEKLKSLSLQQQQQEGDNGDSSKSTEASDFENIESPSNEIDSSASVENRELENQIQISDPENLQSEERSDSDVNNDRSTSSVDSDILSSSHSSDTLCNVDNAPIPLANGLDSHSITSSRRSKANQGKKETWDTAEEDSGTDSEYDESGKSRGETQYMYFKSEPYTADEGSGEGQKWLMVHVDKRITLSAFKQQLEPFVGVPSSHFKVFRVYASNQEFESVRLNETLSSFSDDNKITIRLGRALKKGEYRVKVYQLLVNEPEPCKFLLDAVFAKGMTVRQSKEELLPQLREQCGLDLTIDRFRLRKKTWKNPGTVFLDYHIYEEDINISSNWEVFLEILDGVEKMKSMSQLAVLSRRWRPSEMKLDSFQEVVLESSSVEELKEKLSELSGIPLENIEFAKGRGTFPCDISVLEIHQDLDWNPKVSTLNVWPLYICDDGAVIFYRDKTEELMELTDEQRNELMKKESSRLQKTGHRVTYSPRKEKALKIYLDGAPNKDLTQD
What is the function of this protein?
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER).
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 47, Deubiquitinating enzyme 47, Ubiquitin thioesterase 47, Ubiquitin-specific-processing protease 47.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. USP47 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_RAT
Sequence: MTLDNINRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKNHLKKFNELMVAFRVRPTVLMPLWNVAGFALGAGTALLGKEGGMACTVAVEESIAHHYNNQIRMLMEEDAEKYEELLQVIKQFRDEELEHHDTGLEHDAELAPAYTLLKRLIQAGCSAAIYLSERF
What is the function of this protein?
Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis.  Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.  Involved in lifespan determination in a ubiquinone-independent manner (By similarity).  Plays a role in modulating mitochondrial stress responses, acting in the nucleus, perhaps via regulating gene expression, independent of its characterized mitochondrial function in ubiquinone biosynthesis (By similarity).
What are the official names of this protein?
5-demethoxyubiquinone hydroxylase, mitochondrial, DMQ hydroxylase, Timing protein clk-1 homolog, Ubiquinone biosynthesis monooxygenase COQ7.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RHAD_SHIFL
Sequence: MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIALYHDNFHPQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDEAFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_BRUMB
Sequence: MDDKSMARGRKAFVTGFPIRHSRSPLIHGFWLKELGIDGSYEAVEVKPEDFSSFAASLAANGFAGGNVTIPHKEAAYAAAESLDEAARAIGAVNTLWLENGRLCGGNTDAYGFAANLDASAPGWDKADRALVLGAGGASRAVVHALLSRGVCHVSVVNRTLSRAEELAAHFGARVYAHGWDEAQALVSNAGLIVNTTALGMSGHGEGQDFPIDLTCAPKEAVATDIVYVPLRTAFLNKAEKAGLKTVDGLGMLLHQAVPGFERWFGQRPQVTQALREHILADMAKAGAL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: CSK2B_MOUSE
Sequence: MSSSEEVSWISWFCGLRGNEFFCEVDEDYIQDKFNLTGLNEQVPHYRQALDMILDLEPDEELEDNPNQSDLIEQAAEMLYGLIHARYILTNRGIAQMLEKYQQGDFGYCPRVYCENQPMLPIGLSDIPGEAMVKLYCPKCMDVYTPKSSRHHHTDGAYFGTGFPHMLFMVHPEYRPKRPANQFVPRLYGFKIHPMAYQLQLQAASNFKSPVKTIR
What is the function of this protein?
Regulatory subunit of casein kinase II/CK2.  As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:16818610).  Participates in Wnt signaling (PubMed:10806215).
What are the official names of this protein?
Casein kinase II subunit beta, CK II beta, Phosvitin.
What is the protein family that this protein belongs to?
Belongs to the casein kinase 2 subunit beta family.
Protein: EX53_STRCO
Sequence: MLLDTASLYFRAYFGVPDSVKAPDGTPVNAVRGLLDFIDRLVKDHRPEHLVACMDADWRPHWRVELIPSYKAHRVAEERPAGPDAEEVPDTLSPQVPVIEAVLDALGIARVGVAGYEADDVIGTYTARATGPVDIVTGDRDLYQLVDDARGVRVLYPVKGVGTLNLVDEAALREKYGVDGAGYADLALLRGDPSDGLPGVPGIGEKTAAKLLAEFGDLAGIQAAVDDPKARLTPTQRKRLTEAGPYLAVAPKVVRVAADVPLPDTGTALPHGPRDAAALEALAARWGLGGSLQRLLTTLTA
What is the function of this protein?
5'-3' exonuclease acting preferentially on double-stranded DNA.
What are the official names of this protein?
5'-3' exonuclease.
Protein: DGTL1_THIDA
Sequence: MEPSFAPYAAHSSQTRGRVHREAPAAPRSEFQRDRDRIIHSTAFRRLEYKTQVFVNHEGDLFRTRLTHSIEVAQIGRTIARLLNLNEDLVEAVALAHDLGHTPFGHAGQDALNACMREHGGFEHNLQSLRVVDLLEERYAEFDGLNLTFEAREGILKHCALSNAEKLGEVGRRFIDKKQPSLEAQVANLADEIAYNNHDVDDGLRSGLITLEQLSEVTIFGRHLAEVRRKHPTLQGRRVVTETVRRIINALILDLVDTTRTNVVNSGVETLDDVRNAPPLAAFSPAILEQHRELKRFLLHHLYRHYKVARMSTKAGRIISDLYAAFTGDARLLPPEHQARESLEGTRAVADYIAGMTDRYAMREHRRIYAVEEIYD
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: TRM56_STAMF
Sequence: MKIYVLRYGHRPGRDKRITTHVGLVARAFGAHGFILGDVIDEKVIGSIKKVMERWGGNLYIDAGVDSRKYVLEWKRRGGIVVHLTMYGLHIDDVIDEIRGLNKDILIVVGAEKVPPFFYEVADYNVAIGHQPHSEVAALAVFLDRFYMGKELHLSFPNAKLIIVPSPRGKKVKKIAEEEEGESTKD
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMGF_BACSU
Sequence: MSWIVNKQSSQEELAGRFRKLMSAPDILQIPGAHDGMAALLAKEAGFSAIYLSGAAYTASRGLPDLGIITSAEIAERAKDLVRAADLPLLVDIDTGFGGVLNAARTAREMLEARVAAVQMEDQQLPKKCGHLNGKQLVPIKEMAQKIKAIKQAAPSLIVVARTDARAQEGLDAAIKRSEAYIEAGADAIFPEALQAENEFRQFAERIPVPLLANMTEFGKTPYYRADEFEDMGFHMVIYPVTSLRAAAKACERMFGLMKEHGSQKEGLHDMQTRKELYDTISYYDYEALDKTIAKTVLPDE
What is the function of this protein?
Involved in the methylcitric acid cycle.  Catalyzes the cleavage of 2-methylisocitrate to yield pyruvate and succinate.
What are the official names of this protein?
2-methylisocitrate lyase, 2-MIC, MICL.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.