PharMolix/UniProtQA huggingface dataset:
Protein: DNAJ_RHIRD
Sequence: MAKADFYETLGVSKTADEKELKSAFRKLAMKYHPDKNPDDADSERKFKEINEAYETLKDPQKRAAYDRFGHAAFENGGMGGGGGGFGGGGFANGGFSDIFEDIFGEMMGGGRARRSSGGRERGADLRYNMEITLEEAFTGKTAQIRVPTSITCDVCSGSGAKPGTQPKTCATCQGSGRVRAAQGFFSVERTCPTCHGRGQTISDPCGKCHGQGRVTEERSLSVNIPSGIEDGTRIRLQGEGEAGMRGGPAGDLYIFLSVRPHEFFQRDGADLYCTVPISMTTAALGGTFDVTTLDGTKSRVTVPEGTQPGKQFRLKGKGMPVLRSAQTGDLYIQIQIETPQKLSKRQRELLQEFEQLSSKENNPESTGFFARMKKFFDG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity).
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_ECOSE
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_NITSB
Sequence: MDSYEYSELLKKLEQKIENIKNIIKPDLITKRLKEIEQLENSPDFWNDAKKAGEIQKEKNRLSRILEKFEEARSSVEDAKDLFEMATEEEDTETLNMLFEEAPTLEEKVNKIEIETMLSGENDDKNAIVTIHPGAGGTESQDWASILYRMYLRWAERHGFKVEVLDYQEGEEAGIKDVSFIIKGENAYGYLKAENGIHRLVRISPFDSNARRHTSFASVMVSPEVDDDINIVIEDKDIRVDTYRASGAGGQHVNKTDSAIRITHIPTGIVVQCQNDRSQHKNRATAMKMLKSRLYELELEKKRAEQEGIEKSDIGWGHQIRSYVLAPYQQVKDTRSNKAYSNVEAILDGDIDKIIEDVLIAEAEKESK
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BACC4
Sequence: MGNIHIQTKSKEYDVHVGKEVLSNLTTIVQNMQPAVSNVMIISDEAVASLHLQTVIDALQVEQHVFSFVVPSGEKEKSFENFYAAHTSALENKLDRNSLILALGGGMIGDLAGFVAASFMRGIRFVQVPTTLLAHDSAVGGKVAINHPLGKNMIGAFHQPEAVVYHTPFLQSLPEKEWRSGYAEVIKHALIGDVELYHWLKEEVQTLADLHDEKLIHILTKAIPVKANVVSQDETEKGVRAHLNFGHTLGHALEKELGYGNITHGDGVAVGMLFAIFLSEQVYKVDLAYEDMKQWFLKYGYPKMPRDLNVERLVQLMKQDKKANAGAIHMVLMQEYGVVNVVSISDETVHIALEAFQKDMV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_XANC8
Sequence: MSTPRTIVGVSGGVDSSVAAWKLAQDGEPIAGLFMQNWADDGSGDCRAEDDRRDAVAVCGVLGIPFHFRDFSGEYWSGVFEHFLAEYAAGRTPNPDVLCNREVKFKHFLEAAQALGAERIATGHYARVAHLGGRWRLLRGADRNKDQSYFLHQLGQSQLAATLFPIGELEKSALRRIAQDAGLPTHAKKDSTGICFIGERDFREFLGRYLPARTGEIRDPQGQRIAEHPGVFYFTLGQREGLNIGGVRGRAAAPWYVVGKDVGSNVLYVDQDRDSPLLQSRWLQSEQAHWVTGAPPARSFSCTAQTRYRQPDEPCTVTVQDDGTLQVNFERPQRAVTPGQSLVLYDGEECLGGAVIAATDAPLERQLAGSSFSSEVVA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3S11_HYDPR
Sequence: MKTLLLSPVVVTIVCLDLGYTMTCCNQQSSQPKTTTNCAGNSCYKKTWSDHRGTIIERGCGCPQVKSGIKLECCHTNECNN
What is the function of this protein?
Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.
What are the official names of this protein?
Short neurotoxin 1, Major/minor neurotoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type I alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BTUB_PECAS
Sequence: MIKKISLLTALSVTAFSGWAQETDNNAMVVTANRFQQPVNSVLAPTTVVTREEIDRWQAKSLTDVMRRLPGVDIGQNGGLGQKSSLFIRGTNSSHVLVLIDGIRLNQAGISGSSDLSQIPLSLVQKVEYIRGSRSAVYGSDAIGGVVNIITTREKNGTTLNAGVGSKGYQSYDAATQQALGDSTTATLAGNYVYTKGFDVVAYGTASPAQPDRDGFMSKSLYGTVEHKFGDQFSGFLRGYGYDNRTDYDNFSSVDTRQLYSQTWDTGLRYQSGIYSTQLIGSYSHSKDYDYDPLRGLHSSGSTLVDSQQYNAQWGNVLQVGAGTVSAGVDWQDQIIKPDSTSVNREESQNNTGIYLTGQQRFASIVLEGSVRGDDQSEFGWHNTWRTGASWEFIEGYSLIASYGTAFKAPNMGQLYGRFGSNRDLQPEESKQWESGVEGLTGPVIWRVSGYRNDIDNLIDATGSTGYVYENVGKAKIKGIEATASFDTGPVGHRISYDYVDSRNAITDEPLARRAKQQVKYQLDWQVYDLDWSVTYQYLGSRYDKDYGNYIPAVDDYQTVKLGGVSLWDLAASYPVTSHLTVRGRIANLFDKDYETAYGYRTAGREYYLTGSYTF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: G6PI_MYXXD
Sequence: MTERELWERYQRYLCVVPALDFTLDVSRMRFPADYLERMRPRLEEAFGAMEALEKGAVANPDEKRKVGHYWLRAPELAPEPALQKEITDTVAAIHAFAKNVHEGRVKPQKAQRFTHMLIVGIGGSALGPQLVADALGTAKDPMQVSFFDNTDPDGFDRVLAQLGERLSETLTLVISKSGGTKETRNGMLEAERGYSARGLDFSKHAVAVTGAGSELDNHAKKQGWLRAFPMWDWVGGRTSVTSAVGLLPARLQGLDIDALLKGARDMDAATRERDALKNPAALLALMWHYAGDGRGHKDMVILPYKDRLLLMSRYLQQLVMESLGKETDLDGQVVNQGIAVYGNKGSTDQHAYVQQLREGVLNFFATFIEVLKDRDGGSQEVEPGVTSGDYLLGFLLGTRRALYEKDRESLTLTVPDVSARTLGALIALYERAVGFYATLVHINAYHQPGVEAGKKAAGVVLELQRKLTTRLREARAEARTAEQLAADIGMPDEVETVFKVLQHLAANPDRGVTRTPGATPTQARFQAK
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACPS_FRAAA
Sequence: MAVVGVGVDVVDVDRFAATLSRTPGIAMRLFTPAERGLARPERLAARFAAKEAVAKVLGAPPGLEWHDAEVVLATGGRPSLRIRGTVAAAAQRLDIASWHLSLTHDGGVAIAMVVAES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FKBP_CORGL
Sequence: MEKPQIELPVGPAPEDLVISDIIVGEGAEARPGGEVEVHYVGVDFETGEEFDSSWDRGQTSQFPLNGLIAGWQEGIPGMKVGGRRQLTIPPEAAYGPEGSGHPLSGRTLVFIIDLISA
What is the function of this protein?
PPIases accelerate the folding of proteins.
What are the official names of this protein?
Probable FK506-binding protein, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family.
Protein: PSD_CHLCV
Sequence: MKKLQYIDRSTNQRVTEVVCYEKTMMFLYTSRLGKGVSTLLSRTPFLSRLYGWIQKRSWTRKKIPGFIKKNRICTKEFKKSISEFTSFNDFFTRELRPEARPIARGDDICVTPVDGAYLIYPNIAEFGEFVVKSKRFSLSKLLGDAKLVEKYASGSVVFARLALFDYHRFHFPVDCLAGPTRNINGYLFSVHPMALKDNFNIFCENKRTLTELKTEKFGDVLYLEVGALNVGSIVQTYTAEKKYSKGNEKGFFEIGGSTVIVLFEPGVIQFDADLLKNSRMGLETRCLMGQSLGRSLRE
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type II sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: API_ACAVI
Sequence: MKILSCLLLCTITVLEGNVMNRHNKRFAGFNVAGIGGTAGCVVVDNKLFANGFFLRELTAEEQREFAQYVEESNKYKEELKVSLEERRKGWQIARQSEKGAKILSTITEKNLPKPPKKPSFCTAADTTQYYFDGCMVQNNKIFVGQSYVRDLTADEAKELKSFDVKMTAYQKYLSSSIQQQMNSLFGDKTNLLNLFTNTHLESTSQASEATTIPTTTQTPVEAPETPSFCVPIY
What is the function of this protein?
Aspartyl protease inhibitor.
What are the official names of this protein?
Filarial antigen Av33.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I33 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PURL_STAAT
Sequence: MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTETGIFSVMWSEHCSYKHSKPFLKQFPTSGDHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGGYGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNTSKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTNKAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIYQQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDFEPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGLLSHVQTVGKGGLLITLAKLSAHYGLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNIDNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_STAA3
Sequence: MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLCA_BOVIN
Sequence: MELWPGAGTLLLLLFLLLLLLLPTLWFCSPSAKYFFKMAFYNGWILFLAVLAIPVCAVRGRNVENMKILRLMLLHIKYLYGIRVEVRGAHHFPPSQPYVVVSNHQSSLDLLGMMEVLPGRCVPIAKRELLWAGSAGLACWLAGVIFIDRKRTGDAISVMSEVAQTLLTQDVRVWVFPEGTRNHNGSMLPFKRGAFHLAVQAQVPIVPIVMSSYQDFYCKKERRFTSGRCQVRVLPPVPTEGLKPDDVPALADRVRHSMLTVFREISTDGRGGGDYLKKPGGVGEAGL
What is the function of this protein?
Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
What are the official names of this protein?
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, 1-acylglycerol-3-phosphate O-acyltransferase 1, 1-AGP acyltransferase 1, 1-AGPAT 1, Lysophosphatidic acid acyltransferase alpha, LPAAT-alpha.
What is the protein family that this protein belongs to?
Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CATLL_FASHE
Sequence: MRLFILAVLTVGVLGSNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYWGERGYIRMARNRGNMCGIASLASLPMVARFP
What is the function of this protein?
Thiol protease.  Probably involved in interaction with host tissues.  Displays a similar activity to that of papain.  Has high activity on Z-Phe-Arg-NHMec, but no activity on Z-Arg-NHMec.
What are the official names of this protein?
Cathepsin L-like proteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HUTI_STRPG
Sequence: MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDGLIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEKNLAEFCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITNDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQLTVDRGRIL
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_NITMU
Sequence: MFFAEIKQEEVIVGGFRIGQGFDVHQLVEGRKLVIGGVTIPYEKGLLGHSDADVLLHAICDAVLGAAALGDIGRHFSDTDPRYRNIDSRVLLQNVGNLLAERGYRVVNVDATIIAQAPRMASHIPAMVANIAQDLRMQPGDVNVKAKTAERLGPVGRGEGIEAEAVCLITHMNQTTD
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: BCS1_SCHPO
Sequence: MDNIGAADAATSSGISGLLSGNSFLGAGIGLMGFGAGLAILRRGLISGASLVKRRMLVSVEIPSKEKSYNAFLHWMSTVPKRYSNQLAVESNRQLKMPQNAREKPDKQVANRIFSLVPGPGKHYIKYKKCWIQVERERSNRLQDLTTGTPWETITLTTLSRDRGIFSELLLEAQKFMQSAQKNKTTIYTAWATEWKPFGHPRSKRMLSSVVLESNVKKMITDDVHDFLRNSQWYDTRGIPYRRGYLLYGPPGSGKTSFLYALAGELDYDICVLNLAEKGLTDDRLNHLLSNVPPKAVVLLEDVDSAFQGRERSGEVGFHANVTFSGLLNALDGVTSSDERIIFMTTNHPEKLDPALVRPGRVDVKAYLGNATPEQVREMFTRFYGHSPEMADDLSDIVCPKNTSMASLQGLFVMNKSSPADAVDMAKELPDNPPSTPFSFNVHRKSLSV
What is the function of this protein?
Chaperone necessary for the assembly of mitochondrial respiratory chain complex III.
What are the official names of this protein?
Probable mitochondrial chaperone bcs1, BCS1-like protein.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: DNAA_STRZJ
Sequence: MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFLPRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYSPKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLGKTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLIDDIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQTITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVKKIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVLARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKKKIK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_ENT38
Sequence: MNALTLTPGALTLKQLRGVWRHPTPLVLDENAHEAINQSVACVEAIVAEDRTAYGINTGFGLLAQTRIATHDLENLQRSLVLSHAAGVGAPLDDNMVRLMMVLKINSLARGFSGIRLSVIQALIALVNAQVYPWIPSKGSVGASGDLAPLAHMSLLLLGEGKARWQGEWLPAKDALKKAGLEPITLAAKEGLALLNGTQASTAFALRGLFEAEDLFASAVVCGALTTEAVLGSRSPFDARIHAVRGQRGQIDAAAMYRHVLTDTSEIADSHHNCDKVQDPYSLRCQPQVMGACLTQLRHAAEVLLVESNAVSDNPLVFAEQNEVVSGGNFHAEPVAMAADNLALAIAEIGALSERRIALMMDKHMSQLPPFLVRNGGVNSGFMIAQVTAAALASENKALSHPHSVDSLPTSANQEDHVSMAPAAGRRLWEMASNTRGVLAVEWLAAVQGIDLREGLKSSPLLEQARQTLREAVSHYDDDRFFAPDIEKAMELLDDGRLVALLPPVL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBE_BETVU
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDSLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HAK26_ORYSJ
Sequence: MEYHHRPHSPPPSDDDVVVIQMNAAAIAAVDEWSSTNEVDDAAAGKGGGLTRRTFSQAYKMKHRTPLEFTWRQVALLSFQSLGVVYGDLGTSPLYVFSSISLDDPGEADFVGILSIILWTFTMICLVKYVFIVLKADDHGEGGTFALYSLLRQHVNFKGNMPVPVTHLASDINLKFHSKKRILTSKLLKFLEQSTKWQAVITYIVLAGTCMVLGDGALTPAISVLSAVQGIQSRSSSITQAHVVLLSVIILFILFFFQKHGTSKVSFTFSPIMILWFTFVAFIGLYNIIKHYPPILKAVSPHYIIIYFIRNKRAAWETLGAIVLCITGAEAMFADLGHFNKSSIQMAFSVIVYPSMILAYAGQAAFLVKNPSKLSTTFYSSTPEPLFWPMFIIATLAAIVASQALISASFSIIRQSIALGCFPRVTMKHTSGKHEGQVYSPEINYFLMVACILITVGFKGGPEIGQAFGVAVIFVMLFTTNLMTVVMLIIWESNIALASLFFVFFFSIEGIYMTSLMNKILQGGWVPFAITAFFLIITLSWTYGRSKKGEYELANVMEREEFIKTVTTRSRVPGVCIFCTDMMNGIPPIVRHYVQHVASLRELMVFVTIRVLPVRTVLPEERFIIDKLEPVGVYRCIVQYGYMDNHNMEGDDYVASVIASLKEIAENDDEILVLDSALINGSTFVLGRTIIKMGTRHNCLKRFFINNLYRFLQKNFRSNMSSLKINPGKTLQVGMLYEI
What is the function of this protein?
High-affinity potassium transporter.
What are the official names of this protein?
Potassium transporter 26, OsHAK26.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRC_SHEAM
Sequence: MTHLTLTRPDDWHIHLRDGDSLADTVRDAGRYMGRAIVMPNLVPPVTTTEAAIAYYERIKAHSSTAFEPLMVLYLTDKTSPDEIRAAKASGKVVAAKLYPAGATTNSDSGVTDVNNIYGVLKAMEEEGLLLLVHGEVTDSAIDIFDRERIFIENILSKVVADFPGLKIVLEHITTKDAVDFVMSAGDNVAATITAHHLLYNRNHMLAGGIRPHFYCLPILKRNTHQQALLAAATSGSKKFFLGTDSAPHAKDKKEAACGCAGSYTAHAALELYAEAFEAEGALDKLEAFASFNGPDFYGLPRNADTVALVKSPWQVPESYPLGSTTVVPIRAGEIIGWKVED
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: IRF2_SIGHI
Sequence: MPVERMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARHGWDVEKDAPLFRNWAIHTGKHQPGIDKPDPKTWKANFRCAMNSLPDIEEVKDRSIKKGNNAFRVYRMLPLSERPSKKGKKPKTEKEERVKHIKQEPVESSLGLSNGVSDLSPEYAVLASTIKTEVDSTVNIIVVGQSHLDSNIEDQEIVTNPPDICQVVEVTTESDDQPVSMSELYPLQISPVSSYAESETTDSVPSDEEGAEGRPHWRKRNFEGKQFLSNMGTRSTYLLPSMATFVTSNKPDLQVTIKEESCPMPYNSSWPPFTDLSLPAPVTPTPSSSRPDRETRASVIKKTSDITQSRVKSC
What is the function of this protein?
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes.  Also acts as an activator for several genes including H4 and IL7.  Constitutively binds to the ISRE promoter to activate IL7.  Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth.  Antagonizes IRF1 transcriptional activation.
What are the official names of this protein?
Interferon regulatory factor 2, IRF-2.
What is the protein family that this protein belongs to?
Belongs to the IRF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNY1_CANGA
Sequence: MILASVLKAFQGLQTGLQHSYQDGSPSCPINLPLSCGNETAISDLCCFEYPGGILLMTQFWNYAPSKPNLNRTELEEELGPVDSFTIHGLWPDDCMGGYPQFCKRDLFIDDVDYLLKSDAFNNDDTLPIQGEELLNNLNKYWKSNNGNHESLWIHEYNKHGTCLSTLQPQCYSRWNPTTSQKGPKYYKKKAVYDYFRISYDLFQKLNTYEMLAKHNITPSNDTSYTKSEILSALSSEFQGTQAHINCNSQNALTEVWYYHQLNGSILNEDFIPLDPLRSMSRCKDQGIKYYPKGYQRRDNRGPNKKPISRGTIRISQYGGFLIKTGRWMKRGTPANFELIESKYGNYLLKSRMGYCTVHNDKSQLDCSSRSPDYATQFDYNEEKGILGYSGSFEWGAESAPKNGRTSRSVVFAVSNEKNSNLKYKFQLKFNRK
What is the function of this protein?
Rnase which modulates cell survival under stress conditions.  Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death.  Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration (By similarity).
What are the official names of this protein?
Ribonuclease T2-like, RNase T2-like.
What is the protein family that this protein belongs to?
Belongs to the RNase T2 family.
What are the subcellular locations of this protein?
Vacuole lumen. Cytoplasm. Note=Is released from the vacuole to the cytoplasm during stress conditions like oxidative stress or stationary phase stress.