PharMolix/UniProtQA huggingface dataset:
Protein: SHKA_DICDI
Sequence: MATQQQQQQQQQQQQQIKARKDIQIQQAQSASDILGPPEISETEITTESILGDGSFGTVYKGRCRLKDVAVKVMLKQVDQKTLTDFRKEVAIMSKIFHPNIVLFLGACTSTPGKLMICTELMKGNLESLLLDPMVKLPLITRMRMAKDAALGVLWLHSSNPVFIHRDLKTSNLLVDANLTVKVCDFGLSQIKQRGENLKDGQDGAKGTPLWMAPEVLQGRLFNEKADVYSFGLVLWQIFTRQELFPEFDNFFKFVAAICEKQLRPSIPDDCPKSLKELIQKCWDPNPEVRPSFEGIVSELEEIIIDCCIPDEYGAILWKNHFKHENEANWKDFINVFSNFVGLTNANTPSMSDLLQFSPNLNGSTIELNFKCLKSIIVSSPKGPHEEEVVLMEQFGKVLAWFGNLKEDGSQILDKIRQLMECAWFHGDISTSESENRLRQKPEGTFLVRFSTSEYGAYTISKVSKNGGISHQRIHRPQGKFQVNNSKYLSVKELITGEAQALGINTPCLGSRFLSLIYKAQLSGYIN
What is the function of this protein?
Required for proper chemotaxis and phagocytosis; proper spatiotemporal control of F-actin levels in chemotaxing cells.  Negative regulator of the PI3K (phosphatidylinositol 3 kinase) pathway.  Predominantly phosphorylates serines and threonines and tyrosines at a lower level.
What are the official names of this protein?
Dual specificity protein kinase shkA, SH2 domain-containing protein 1, SH2 domain-containing protein A.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. SH2 domain-containing protein kinase subfamily.
What are the subcellular locations of this protein?
Membrane.
Protein: GPT_CRIGR
Sequence: MWAFPELPLPLLVNLFGSLLGFVATVTLIPAFRSHFIAARLCGQDLNKLSRQQIPESQGVICGAVFLIILFCFIPFPFLNCFVEEQCKAFPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPFRWILGLHLDLGILYYVYMGLLAVFCTNAINILAGINGLEAGQSLVISASIIVFNLVELEGDYRDDHVFSLYFMIPFFFTTLGLLYHNWYPSQVFVGDTFCYFAGMTFAVVGILGHFSKTMLLFFIPQVFNFLYSLPQLLHAIPCPRHRIPRLNPKTGKLEMSYSKFKTKNLSFLGTFILKVAERLQLVTVHRGESEDGAFTECNNMTLINLLLKIFGPIHERNLTLLLLLLQILSSAVTFSIRYQLVRLFYDV
What is the function of this protein?
Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
What are the official names of this protein?
UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-P transferase, G1PT, GPT, N-acetylglucosamine-1-phosphate transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PCKA_COXB2
Sequence: MEQIAARVTYINLSPDELIQHAVKNGEGVLSSTGALAVTTGKRTGRSPKDRFIVKDEQTADQVAWGNINQPVEQRTFDQLWERALRYLSERAVYISHLQVGADDNYFLPLKVVTEFAWHNLFACDLFIRPSGDHANGKPSWVILSAPGLKTDPERDGVNSDGAVMINLSQRRVLLVGMPYAGEIKKAMFSVLNYLLPPHDVLPMHCAANAGQSGDVALFFGLSGTGKTTLSADPHRFLIGDDEHGWSATSVFNFEGGCYAKCIDLSQEREPMIWNAIRHGAIMENVVLDENGVPDYADARLTQNSRAAYPREYIPLRVENNRGRPPDAVLFLTCDLDGVLPPVALLTKEQAAYYFLSGYTALVGSTEVGSVKGVTSTFSTCFGAPFFPRPPTVYAELLMKRIEATGCQVYLVNTGWTGGAYGKGGERFSIPTTRAIVNAVLSGKLKEGPTEVLSGFNLTIPKSALGVDDHLLNPRKTWEDVSAYDVRAQRLIQKFRENFEKFKVPAAIREAGPSDVH
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DET1_YEAST
Sequence: MCEENVHVSEDVAGSHGSFTNARPRLIVLIRHGESESNKNKEVNGYIPNHLISLTKTGQIQARQAGIDLLRVLNVDDHNLVEDLAKKYIKDESSRRTLPLKDYTRLSREKDTNIVFYTSPYRRARETLKGILDVIDEYNELNSGVRICEDMRYDPHGKQKHAFWPRGLNNTGGVYENNEDNICEGKPGKCYLQYRVKDEPRIREQDFGNFQKINSMQDVMKKRSTYGHFFFRFPHGESAADVYDRVASFQETLFRHFHDRQERRPRDVVVLVTHGIYSRVFLMKWFRWTYEEFESFTNVPNGSVMVMELDESINRYVLRTVLPKWTDCEGDLTT
What is the function of this protein?
Metal-independent, broad-range acid phosphatase.  Involved, either directly or indirectly, in the bidirectional transport of sterols between the endoplasmic reticulum and the plasma membrane.
What are the official names of this protein?
Broad-range acid phosphatase DET1, Decreased ergosterol transport protein 1.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CSK_CHICK
Sequence: MSGMQAVWPSGTECIAKYNFHGTAEQDLPFSKGDVLTIVAVTKDPNWYKAKNKVGREGIIPANYVQKREGVKAGIKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIIYSSSKLSIDEEVYFENLMQLVEHYTTDADGLCSRLIKPKVMEGTVAAQDEFSRSGWALNMKDLKLLQIIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVMTQLRHSNLVQLLGVIVEEKSGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCEAMEYLEANNFVHRDLAARNVLVSEDNIAKVSDFGLTKEASSTQDTGKLPVKWTAPEALREKKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDPPDGCPAIVYEVMKKCWTLDPGHRPSFHQLREQLVHIKEKELYL
What is the function of this protein?
Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response.  Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases (SFKs).  Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation.  To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane (By similarity).
What are the official names of this protein?
Tyrosine-protein kinase CSK, C-Src kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_CORGL
Sequence: MTIKVAIAGASGYAGGEILRLLLGHPAYASGELEIGALTAASTAGSTLGELMPHIPQLADRVIQDTTAETLAGHDVVFLGLPHGFSAEIALQLGPDVTVIDCAADFRLQNAADWEKFYGSEHQGTWPYGIPEMPGHREALRGAKRVAVPGCFPTGATLALLPAVQAGLIEPDVSVVSITGVSGAGKKASVALLGSETMGSLKAYNTSGKHRHTPEIAQNLGEVSDKPVKVSFTPVLAPLPRGILTTATAPLKEGVTAEQARAVYEEFYAQETFVHVLPEGAQPQTQAVLGSNMCHVQVEIDEEAGKVLVTSAIDNLTKGTAGAAVQCMNLSVGFDEAAGLPQVGVAP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUP_BIFDB
Sequence: MPQEFEQIRSADQPLDSEESAPVAGARTDDTVDALDAVLDDIESVLETNAEEYVGSFVQKGGE
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: HBA_PHOVI
Sequence: VLSPADKTNVKATWDKIGGHAGEYGGEALERTFTAFPTTKTYFPHFDLSHGSAQVKAHGKKVADALTTAVAHMDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLACHHPADFTPAVHASLDKFFSAVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: Y1570_COREF
Sequence: MPYDYDLRCPCGTGLTYGQCCHRYHAGNHHAPTAEALMRSRFTAFAAGETDYLLDTWDPATRPAELTLDDRLEFYRLEILETEGGGPFDATGRVKFQAFHRGLADGVQEEDSTFRKMDGRWVYSLGDVAE
What are the official names of this protein?
UPF0225 protein CE1570.
What is the protein family that this protein belongs to?
Belongs to the UPF0225 family.
Protein: YIDC_RICRO
Sequence: MNNNIINLIAAIILSLSIIFGWQYFVVKPEQKKQQQQIAVQKAENLKKQQLKALVEPATGIVVQEESQVQRIKIESESLTGSISLKGLRFDDLILKKYKQDLSKNSSEVRLFSPANTENAYFAEVGLVSNLSSVKLPNNDTIWNSDSEILSPEKPVHLFWVNEDGVKFLVTITVDENYLFTIEQTIVNNSDKELPVQSYGLINRKYIAVEKAVNILHQGPIGCIDENLKEYSYDDIKDKKSEKFAASKVDWIGITDKYWLSSLIPDKSSNYSSNFNYALKQGIERYQVDFISPVQIIKPGKNFSIKSRIFAGAKKVDLLDKYEKQYDIKLFDRAIDFGWFYIITKPVFYAMNFFYGYVGNFGVSILIVTVIIKLLMFTLANKSYRSMKKMKNLQPEIDRIKNLYSDDKARLNQEIMALYKKEKVNPVAGCLPILVQIPVFFSIYKVLYVTIEMRQAPFYGWIKDLSAPDPTTIFNLFGLLPFAPPSFLMIGAWPILMAITMFLQQKMSPEPADPMQAQVMKFMPLIFLFMFSSFPVGLLIYWSWNNILSIIQQYYINKFN
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RISB_ALKCK
Sequence: MGKNYEGHLVASGLKVGIVVGRFNEFITSKLLGGAQDGLIRHGADEGDIDVAWVPGAFEIPFAAKKMAESGRYDAVITLGTVIRGSTPHFDYVCNEVAKGVSSLALTTGIPVIFGVLTTDTIEQAVERAGTKAGNKGWEAASAAIEMANLAKQFEE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: UNG_WOLSU
Sequence: MIMADLERIKIEPSWKEVLKEEFTKPYFDSIRESYLQAKSSGAILYPPAPLLFNAFNLTPFDQVKAVILGQDPYHAPHQAMGLCFSVPKGVALPASLRNVYKELERDLGIPPAKHGDLTSWAKQGVFMLNAILSVEQGKAGSHQKFGWQTFTDAAISALSRKKKGVVFLLWGNFAREKRVLIDSTKHTILESAHPSPLAGNRYFGNGHFSKTNEILKVQGEREILWRLPE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_THEKO
Sequence: MAHVAEWKKKEVEELANIIKSYPVIALVDVAGVPAYPLSKMRDKLRGKALLRVSRNTLIELAIKRAAQELGQPELEKLIDHIQGGAAILATEMNPFKLYKLLEESKTPAPAKAGAVVPKDVVIPAGPTSLAPGPLVGEMQALGIPARIEKGKVSIQKDYTVLKAGEVITEQLARILNALGIEPLEVGLNLLAAYEDGIVYTPDVLAIDESEYINMLQKAYMHAFNLSVNIAYPTKQTIEAILQKAYLGAKNVAVEAGYITKDTVEDIFGRAIRAVLLIAQNLPEDLLDEKTKELLNAQAQMAVAAAPQPTEEKVEEAEEEEEEEEASEEDALAGLGALFG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RD22_ARATH
Sequence: MAIRLPLICLLGSFMVVAIAADLTPERYWSTALPNTPIPNSLHNLLTFDFTDEKSTNVQVGKGGVNVNTHKGKTGSGTAVNVGKGGVRVDTGKGKPGGGTHVSVGSGKGHGGGVAVHTGKPGKRTDVGVGKGGVTVHTRHKGRPIYVGVKPGANPFVYNYAAKETQLHDDPNAALFFLEKDLVRGKEMNVRFNAEDGYGGKTAFLPRGEAETVPFGSEKFSETLKRFSVEAGSEEAEMMKKTIEECEARKVSGEEKYCATSLESMVDFSVSKLGKYHVRAVSTEVAKKNAPMQKYKIAAAGVKKLSDDKSVVCHKQKYPFAVFYCHKAMMTTVYAVPLEGENGMRAKAVAVCHKNTSAWNPNHLAFKVLKVKPGTVPVCHFLPETHVVWFSY
What is the function of this protein?
Acts to suppress chlorophyll degradation under moisture stress.
What are the official names of this protein?
BURP domain protein RD22, Dehydration-responsive protein RD22.
Protein: PSTS_STAAW
Sequence: MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSSTVAPIVEKLNEKWAQDHSDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQDKNIKYKEFKIAQDGVTVAVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKINAVSPNSSHGTYDFFENEVMNKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQNKDKLKEVKIKDENGKATEPTKKTIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVLEDKGKAAEEAGYVAAPEKTYKSQLDDLKAFIDKNQKSDDKKSDDKKSEDKK
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.
What are the official names of this protein?
Phosphate-binding protein PstS, PBP.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL6_BEII9
Sequence: MSRIGKKPVVIPAGVTAKVEGQAISVKGGKGELHFTAPDYVSVALEGTQIAVSPRSEDKKARAAWGMTRSIVNNLVIGVSQGFERKLEITGVGYKAAVQGKNLQLSLGYSHDISFPIPDGIAIAAPKPTEVSITGIDKQRVGQIAAEIRALRPPEPYKGKGVKYAGEFIFRKEGKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RL15E_THEAC
Sequence: MSSSGLYQAVREEWKSLKKSEIYDLVKKRMIEWRHGPSIVRLEHPTRIDRARALGFKSKDGFIVVRSRVRRGGSNREKIMGGRRPRRMAYNKLTRKKSLKLIAEERAADKYPNMEVLNSYYVGEDGLYKYFEVILVDRSHPNIFNDPHISWISEPQNTGRVYRGLTSAGYKVRGLRTGRKGSSKSRPSIRSNGRLRR
What are the official names of this protein?
50S ribosomal protein L15e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
Protein: RL9_RHIME
Sequence: MEVILLERIAKLGQMGETVKVRDGFARNYLLPLGKALRANAANKARFESERSTLEARNLERKSEAQKVADSLDGKSFIIVRSAGETGQLYGSVAARDIVETLAAEGFNINRNQVDLNQPIKAIGLHKVTLHLHGEVDVAIEINVARSAEEAERQAKGESLTSADAIYGVDEDALKPEDFFNPEAELESEEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: MNME_LEPCP
Sequence: MLPRHHEPIAAIATAPGRGAVGIVRVSGRGLTALATALVGRPLRPRVASYGPFLDRQGGAIDRGLALHFPAPHSYTGEDVLELQAHGGPVVLQLLLARCLEAAGEIGTDGRPRLPGLRLAQPGEFTERAYLNDKLDLAQAEAVADLIDASTEAAARSAARSLSGDFSRQITHLRDGLIELRALVEATLDFPEEEIDFLQRADAHGRLARLAERLAGLLDTARQGALLREGLRVVIAGQPNAGKSSLLNALAGAELAIVTPIPGTTRDKISETIQIEGVPVHVIDTAGLRSDEQAGDEVERIGISRSWQAIAEADAVLLLHDLTREHEPAYSAADTAIAQRLPADVGLIHVHNKADAAPEQAARVAARLAARQAGDAAGVVLSARTHDGIDALRAALLARAGWHAAPEGVFIARERHVRALRAAATHVTAAQGWAEQSDSALDLLAEELRSAHDALAEITGSYSSDDLLGDIFGRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDHS_BRUA1
Sequence: MSGSYPFIDIAALDSVREGFARGDAQLVLAHDLSTVLWVNGPGAKLFGYNRVEDLIEGQLDLPVATRRQIAAFSSENTSAPSAVAVRLGGGLRSELTHLHVSNIKLPDGVAALLVATQMPDNSAEAAISGLGDDSTHIALVDAVGKVVAASPRFALLDISASTLEDLIVEAGDATDRIVKRRIRTGSHSVPGAIARLTDTPALHLLCIVGDAPAQFQTAAEAVPLPDNAEAVLEEILPEQGDAPAQQAQKTHAEQPRPKTFAFDHDAPPARFIWKVGPDGTFSEISPNLAAVVGPNSADIVGRRFSDVANVFGFDTDGSIAALLLERDTWSGKRLLWPVEGTRLRVPVELAALPVYSRDREFLGFRGFGIVRPAEAEADPEEIGLALAGGIPQNRKPRKEPAETARMVGEDDVLALSEEVANDDQPAAVLPKPPLDITPTPGRRDSDKVISLLNSCAQEKVAADQAKFLKEKERATRPEGGLTKTERNAFREIAERLRKQGLANTRAESETPVSETSSIEPVEPTPPVKTRSEPIQPDETALLANLPVPVIIHSGDAIHYVNQALLDITGYESLDDIRSAGGVDVLFNSESDDGETRQSMLLRHADGSEEPVDAHLNAIAWRGGRALMLSLMPVTAADLPAPAELPAANDEEKQALEAHVEELKTILDTATDGVVLIDPEGRIRSMNHSASALFGYERDEAEGKFFSMLFAIESQRAAMDYLHGLSGNGVLSVLNDGREVIGREAKGGFIPLFMTIGKLPHTRGFCAVLRDITQWKRTEEELTNARKEAERASNQKTEFLARISHEIRTPLNAIIGFSELMADEKFGPIGNDRYRDYLRDINRSGNHVLALVNDLLDISKIEAGALDMQFEAVSLNDAIGEAIALMQPQANRERVIIRSSFQSNLPDIVADSRSIKQVALNLLSNAVRFTAPGGQVIVSTSYELNGDVVMRVRDTGIGMSKSEVEQALKPFRQINALERRKAESAKDWRNEGTGLGLPLTKAMVEANRAQFAIDSNPGQGTVVEIVFPPTRVLAD
What is the function of this protein?
Functions as a polar differentiation marker.  Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon.  The asymmetrical localization of this protein is probably required for cells to enter a new division cycle (By similarity).
What are the official names of this protein?
Cell-division control histidine kinase PdhS.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes at the old pole of dividing cells. Colocalizes with DivK (By similarity).
Protein: RS5_NITMU
Sequence: MAKMQGRMQGKVAPGDDRGDGLKEKMVAINRVTKVVKGGRILGFAALTVVGNGDGGVGMGKGKSREVPVAVQKAMDEARRKMIKVSLKNGTLQHPVIGRHGAAKVYMQPASEGTGIIAGGPMRAIFEVMGVHNILAKCIGSTNPYNVVRATLNGLQAMSNPAEIAAKRGKSVEEILGLEK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: SET1_YARLI
Sequence: MANGSDTKPVPKGPRGARADDTRTPPHPDRRGSDRDQYFSKDRSYGGRTDRDYSDYDRAYPPPRDYDRYGGGKYGKYDKYDKYDRYDRLDSHDYPPRRDRDYDRSRDARDTDSRDYGRLPPRDTRPPPRGGREYRYARDERGWDRDRRDLDRDRDRDPRDRERDARDRDRDRDFRDRDHDPRDRDPKGYRPHSLDPLPSRDRDMPPRERERELVRERDLFSRDRDLITGVRELARSPPPPLRDGRNRDRSNDRHDRSFDKHTRDRGTRDRDTKEKGSVISTPQTAPTPRLTPTNGKPDLPTSQPPAPPSPPRLKTFPKEVWETVGRKNNTRLTYDPELSKDKQKGKRGIYEEVKKGASTTEDPRSKHPHYFKTSSKSNKKPYQRLPVPRFLYDANSIAPPPSTQIIVKGLSSLTTSKTITAHFKTYGELEAVNMVEDPATGSSVGACLVRFKVTKNNYEAAHECLKKAIRGQKTGRIDQAKYRVEPDEDGAKAKDIIKRVAARAAKKAMPVKQPPTAPAADKSIMEKLPTPVPSARPSPKAAQLMKTSAYIFIAGKYLPSEKVFASDIRRILRDFGWFDVLKEGDGFYVFFDNNRDTVECYEAMNGRKVNGHQMAMAMIRLSRVAPKTKESEENATEQAPKLPPKEEARKLIVQELANSLRKDIRERVIAAAIVEFLNPARFTHIKQDPEPSAATEPNTVNASAARVDTPEPVQSSSAIPGFLPRFKIKRKGDPTKKKDATKKNRKKISARPMNHVLNDYYSDEEDSTRMSTPIVPDTSADAAELPIRKPRKKISQSKQRIMDFSSSEGSNESEEEEEVEDDMEEEEDETAQEELQEASTLDTSQQLTTAFGEILDWAPAHGFPQPVTADKKGGALTTISGFQALVKDDEDMELLQEALEGIEPEKINGEAWTWTHKHLNEAVAKENAEFPELAAPNAFVNSTGSWKSQGYFKIPEAAKSEYLPHRKKLNIPIDTLQMENREKKKENASNSRVNRANNRRLVADINMQKQLLSTETDVLNFNQLRKRKKPVKFARSAIHNWGLYAIEPIAANEMIIEYVGEVVRQEIADLREARYMRSGIGSSYLFRVDESTVVDATKRGGIARFINHCCTPSCTAKIIKVEGQKRIVIYASRDIAANEELTYDYKFEKEIGEERIPCLCGAPGCKGYLN
What is the function of this protein?
Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
What are the official names of this protein?
Histone-lysine N-methyltransferase, H3 lysine-4 specific, COMPASS component SET1, SET domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TF2H3_HUMAN
Sequence: MVSDEDELNLLVIVVDANPIWWGKQALKESQFTLSKCIDAVMVLGNSHLFMNRSNKLAVIASHIQESRFLYPGKNGRLGDFFGDPGNPPEFNPSGSKDGKYELLTSANEVIVEEIKDLMTKSDIKGQHTETLLAGSLAKALCYIHRMNKEVKDNQEMKSRILVIKAAEDSALQYMNFMNVIFAAQKQNILIDACVLDSDSGLLQQACDITGGLYLKVPQMPSLLQYLLWVFLPDQDQRSQLILPPPVHVDYRAACFCHRNLIEIGYVCSVCLSIFCNFSPICTTCETAFKISLPPVLKAKKKKLKVSA
What is the function of this protein?
Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.  In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment.  In transcription, TFIIH has an essential role in transcription initiation.  When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.  Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
What are the official names of this protein?
General transcription factor IIH subunit 3, Basic transcription factor 2 34 kDa subunit, BTF2 p34, General transcription factor IIH polypeptide 3, TFIIH basal transcription factor complex p34 subunit.
What is the protein family that this protein belongs to?
Belongs to the TFB4 family.
Protein: H2A1D_HUMAN
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-D, Histone H2A.3, Histone H2A/g.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CRR3_XENRU
Sequence: GIGSALAKAAKLVAGIV
What are the official names of this protein?
Caerulein precursor fragment-related peptide R3, CPF-RP-R3.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNX_BACFN
Sequence: MKKIECIIMDWAGTAVDYGCFAPVAAFIKAFAGKGLTIDVEQTRKPMGLPKIQHIRELLTMPEVNEQFINRYRRAWTEEDVVELNHLFEKYLFASLKEYTDPIPGVIPTLEKLRAEGLKIGSTTGYTREMMDVVLPEAQAKGYRVDYCATPNLLPAGRPAPYMIFENLTKLAVPDPDTVVKVGDTIADIQEGVHAKVWSVGVVLGSNEMALTEEETHALPAAELENRIAEVKQRMLAAGASYVIRSIEELPALIQLINSKLNH
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: RS15_META3
Sequence: MARLHSGKRGSSGSTRPLRTEVPAWANITAEETEEVIVKMAKEGKQSAMIGLILRDSYGIPDVKLVTGKSVAQIMKDNNVYPEIPEDLFNLMKKAINLRNHLEENTKDIHSKRGLQLTESKIRRLVKYYRNTKVLPAKWRYSPETARLLVE
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: APOA1_SALTR
Sequence: MKFLALALTILLAAATQAVPMQADAPSQLEHVKVAMMEYMAQVKETGQRSIDLLDDTEFKEYKVQLSQSLDNLQQYAQTTSQSLAPYSEAFGAQLTDAAAAVRAEVMKDVEDVRTQLEPKRAELKEVLDKHIDEYRKKLEPLIKEIVEQRRTELEAFRVKMEPVVEEMRAKVSTNVEETKAKLMPIVETVRAKLTERLEELRTLAAPYAEEYKEQMFKAVGEVREKVGPLTNDFKGQVGPAAEQAKEKLMDFYETISQAMKA
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.