PharMolix/UniProtQA huggingface dataset:
Protein: PLSY_CHLL2
Sequence: MLTLLAILAVSYLIGSIPTGIMAGKMLKGIDIRKFGSGNAGGTNAFRVLGWKTGLTVTLIDIIKGVVAAVSVVAFFRHHPIDVFPDINEVALRLLAGMSAVVGHVFTVFAGFKGGKGVSTAAGMLIGIAPVSMLMVIGIFLLTIYLSRYVSVASMLAAVAFPLIIAIRKYIFELGSGLDYYIKLFGEQLSFHDSLDYHLMIFGLIVALGILYTHRANIRRLLSGTENRVTFGKHS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPL_NITOC
Sequence: MDPELLVSIYASTAVSVGIILAAAGLGSALGWGLICSKYLEGIARQPEMRPQLMGQMLFTGGLMEAFPMIVLGMSMWFIFANPFTGAALAAIGS
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GRPE_ERWT9
Sequence: MSSKEQNTPNEQASDEIETEQAKNQGADTAAEAADQRDERIAQLEAQLAESQGGVRDAQLRAQAEIENIRRRAELDVEKAHKFALEKFSNELLPVIDSLERALEVADKSNPELAAMIEGIDLTMKSLLGAVRKFGVEVVGDTNVPFNPEVHQAMSMMESEEVEPNHVMMVMQRGYTLNGRLLRPAMVAVAKSKG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPPA_METM6
Sequence: MLFLNAKFIDLDLGENAVIVNDEDLKGTSYYPQDRVLIESHAGAVIGNIYSTKTMVKKGEVGMLVKELKEVSISEGEEVKLRHAEKPESIPFIKKKMDGQVLNPHEIRTIIDEIVSKKLSNIELSAFVSSTYINGMNMDEISEMTKRIAETGDMISWEKSLVVDIHSIGGVPGNKYALLSIPILAAAGITIPKTSSRAITSPAGTADVMEVLTNVELKEEEIKRIVKTTNGCLAWGGGVNLAPADDIIINVERPVSIDPQPQLLASVMAKKIATGIKYTVIDIPVGKGVKIKNEAEGAKLARKFIELGELLNIKVECVLTYGGQPLGRAIGPALEAREAIEALQDPKNAPKSLIEKALSLAGILLELGGAAQIGEGQKLAWEILESGRALEKFNQIITEQGGTPKKPEEIELGEYVEEIIAPIDGYITDISNTAITNVVKEAGAPRDKKAGILLNSKIGNQVKQGDILYTIYSGSEERLVSAVNLARRVYPVKVEGMLIERISKF
What is the function of this protein?
Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P).  Exhibits phosphorylase activity toward CMP and UMP in addition to AMP.  Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.
What are the official names of this protein?
AMP phosphorylase, AMPpase, Nucleoside monophosphate phosphorylase, NMP phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: ATG12_PICAN
Sequence: MSDKDLASSLMELNIKVGTTDIPQTIAEEQNQVTDTKEEVLDDETTIKNDPQKTKITLNQSMMLSKLPAKTTSAVLSVSKPTESKIQIRFKSIGSVDQVSPAVFKISKSSKFSSILRFLELKLGKKVYCYLNNSVSPNPDEELENLYNIFRVGDELIVSYCNIVAFG
What is the function of this protein?
Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.  Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function.  The ATG12-ATG5 conjugate functions as an E3-like enzyme which is required for lipidation of ATG8 and ATG8 association to the vesicle membranes (By similarity).
What are the official names of this protein?
Ubiquitin-like protein ATG12, Autophagy-related protein 12.
What is the protein family that this protein belongs to?
Belongs to the ATG12 family.
What are the subcellular locations of this protein?
Preautophagosomal structure membrane; Peripheral membrane protein.
Protein: CBID_SYNJB
Sequence: MQDAVQGSRPRGYTLPVFAVASARAALHHLLGIPLEKEGGRLVVAVQAEPQSLEARIHIPVEQVAALEKTTALAITRSDPGPHLDLTRDTPVWAWVRLEERDPEDPPLILEAGEGLGRRTDGSPAIYAYARRLFEINLLPGIPPDCRLRVRIILPEGKLLAERTSNAAFGVLEGLALLGTRAEVEPSSSVESLEQARQELQQKLERHKHLIFCVGSHGQQVALRQGIPEDQILRVANWIGPLLVEAALRGAESIHLIGYHGKLIKLAGGIFTTSSHVADARLEILAAALIRRGGTAEQARQVLELRTVEAAVHYLDGLGWAAPVMQELARQILERATGYVQKYAGRSLLLAVTLFDRQGQICAQVGIP
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: TELL_STAEQ
Sequence: MVSEQSSNRSHPLDYYMDNQSTDHHTIAEDLEMQLTENDKQRIKSISEQIEPLNHEGLLKYGANLQQKMSHFSHQILDDVQSKDMGPVGETLSQLMGKLKSVNPNDINPEKQSRLKRLFKRTKASINEVFSRMQSVSSQIDRITIQLEKHKDQLTKDVEFLDQLYQENKTYFDNVSLYILAAQKKKKEILTETIPQLREKAHQTGNQMDIQATADMEQFVDRLDKRIYDLQLSRQIAIQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTLMRQRNAVSAQRSVTDTTNELLTQNASMLKKNAIETAAENERGIVDIETLKTTQNDIIETIEQTLQIQEDGRQKRQVAEKELNELEQDLKQHLLSMRK
What are the official names of this protein?
TelA-like protein SERP0976.
What is the protein family that this protein belongs to?
Belongs to the TelA family.
Protein: TRA2_DROME
Sequence: MDREPLSSGRLHCSARYKHKRSASSSSAGTTSSGHKDRRSDYDYCGSRRHQRSSSRRRSRSRSSSESPPPEPRHRSGRSSRDRERMHKSREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPRGKAPRSFSPRRGRRVYHDRSASPYDNYRDRYDYRNDRYDRNLRRSPSRNRYTRNRSYSRSRSPQLRRTSSRY
What is the function of this protein?
Required for female sex determination in somatic cells and for spermatogenesis in male germ cells.  Positive regulator of female-specific splicing and/or polyadenylation of doublesex (dsx) pre-mRNA.  Splicing requires an enhancer complex, dsxRE (dsx repeat element: which contains six copies of a 13-nucleotide repeat and a purine-rich enhancer (PRE)).  DsxRE is formed through cooperative interactions between tra, tra2 and the sr proteins, and these interactions require both the repeat sequences and PRE.  PRE is required for specific binding of tra2 to the dsxRE.  Protein-RNA and protein-protein interactions are involved in tra-2 dependent activation and repression of alternative splicing.  Together with tra-2, plays a role in switching fru splicing from the male-specific pattern to the female-specific pattern through activation of the female-specific fru 5'-splice site.
What are the official names of this protein?
Transformer-2 sex-determining protein.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
Protein: MIAB_MYCS2
Sequence: MVTRDETAEAEGLRPAVGSSRVRTYQVRTYGCQMNVHDSERLSGLLESAGYQRAAEGTDADIVVFNTCAVRENADNKLYGNLSHLAPRKQADPNMQIAVGGCLAQKDRDAVLRRAPWVDVVFGTHNIGSLPTLLERARHNREAQVEIVEALQEFPSALPASRESAYAAWVSISVGCNNTCTFCIVPSLRGKEVDRRPGDILAEVQSLVDQGVLEITLLGQNVNAYGVSFADPELPRDRGAFAKLLRACGGIDGLERVRFTSPHPAEFTDDVIEAMAATPNVCPTLHMPLQSGSDRILKAMRRSYRAERFLGIIDKVRAAIPHAAITTDLIVGFPGETEEDFQATLDVVEQARFAGAFTFQYSKRPGTPAADMPDQLPKSVVTERYQRLIELQERISLEQNREQVGRAVELLVATGEGRKDASTARMSGRARDGRLVHFLPGDNEIRPGDIVTTTVTGAAPHHLIADAPIIERRRTRAGDAHAAGQKPRTGVGLGMPRIGAPAPSATAEGCGC
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FEN_KORCO
Sequence: MGVKIGELIEDKVELELSDIAGKKIALDAFNAMYQFLAKVRQPDGTPLMTSKGEITSVHSGIFYRTANFLKEGIIPIYVFDGEKPSFKSRAIEERVRAREEAELKWKEALEIGDLEEARKYAQAALNITGDIVEDCKTILKLMGVPIVQAPSEGEAQAAHMAMKGDVWATASQDYDSLLFGAPRLIRNLTITGKRKLPGKEVYVDINPELIELESVLKRNGISREQLIMIGILVGTDYNLGGVKGIGVKRALELVKKYKRPEDLFSKVPWEFDVDPISIYEFFLNPPTTDDYDTSLKRPMSDELLKFMVEEHEFSEERVKKVINEIEESYRMLSGGGLESWF
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity.  Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation.  Also involved in the base excision repair (BER) pathway.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA (By similarity).
What are the official names of this protein?
Flap endonuclease 1, FEN-1, Flap structure-specific endonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
Protein: NADD_TRIL1
Sequence: MKLGLLGGTFNPIHLAHLRIAEEAREAAGLDQVLFIPAADPPHKPLAGDVSFELRAAMVQRAIAANPAFRFSDIEAHRAGKSYTVDTLTALRTARPGDELHFIIGSDSFLELGLWHRYADIFPLASLIVLERPEKAITEPLQQLPELVRDQFVQEAGNLVRHSSGTSIRFVIGTRLDISSSQLRERVARQQSIRYLVPPEIESFITQKGLYQP
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: PPR36_ARATH
Sequence: MVKLMIRRLSSQVSKFVQPRLLETGTLRIALINCPNELSFCCERGFSAFSDRNLSYRERLRSGLVDIKADDAIDLFRDMIHSRPLPTVIDFSRLFSAIAKTKQYDLVLALCKQMELKGIAHNLYTLSIMINCFCRCRKLCLAFSAMGKIIKLGYEPNTITFSTLINGLCLEGRVSEALELVDRMVEMGHKPDLITINTLVNGLCLSGKEAEAMLLIDKMVEYGCQPNAVTYGPVLNVMCKSGQTALAMELLRKMEERNIKLDAVKYSIIIDGLCKHGSLDNAFNLFNEMEMKGITTNIITYNILIGGFCNAGRWDDGAKLLRDMIKRKINPNVVTFSVLIDSFVKEGKLREAEELHKEMIHRGIAPDTITYTSLIDGFCKENHLDKANQMVDLMVSKGCDPNIRTFNILINGYCKANRIDDGLELFRKMSLRGVVADTVTYNTLIQGFCELGKLNVAKELFQEMVSRKVPPNIVTYKILLDGLCDNGESEKALEIFEKIEKSKMELDIGIYNIIIHGMCNASKVDDAWDLFCSLPLKGVKPGVKTYNIMIGGLCKKGPLSEAELLFRKMEEDGHAPDGWTYNILIRAHLGDGDATKSVKLIEELKRCGFSVDASTIKMVIDMLSDGRLKKSFLDMLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g12300, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MATRX_PIV5
Sequence: MPSISIPADPTNPRQSIKAFPIVINSDGGEKGRLVKQLRTTYLNDLDTHEPLVTFINTYGFIYEQDRGNTIVGEDQLGKKREAVTAAMVTLGCGPNLPSLGNVLGQLREFQVTVRKTSSKAEEMVFEIVKYPRIFRGHTLIQKGLVCVSAEKFVKSPGKIQSGMDYLFIPTFLSVTYCPAAIKFQVPGPMLKMRSRYTQSLQLELMIRILCKPDSPLMKVHTPDKEGRGCLVSVWLHVCNIFKSGNKNGSEWQEYWMRKCANMQLEVSIADMWGPTIIIHARGHIPKSAKLFFGKGGWSCHPLHEVVPSVTKTLWSVGCEITKAKAIIQESSISLLVETTDIISPKVKISSKHRRFVKSNWGLFKKTKSLPNLTELE
What is the function of this protein?
The M protein has a crucial role in virus assembly and interacts with the RNP complex as well as with the viral membrane.
What are the official names of this protein?
Matrix protein, Membrane protein.
What is the protein family that this protein belongs to?
Belongs to the morbillivirus/respirovirus/rubulavirus M protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RIMO_SALAR
Sequence: MSNVTHQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPRYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITGPHSYEQVLQHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIPSMRGDLVSRPIGDVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMASLCEQLSKLGVWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWRDICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCFKYSPVEGAGANELPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIVDEVDEEGAIGRSMADAPEIDGAVYLNGETNVKPGDIVRVKVENADEYDLWGSRV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GK_HHV19
Sequence: MLAVRSLQHLSTVVLITAYGLVLVWYTVFGASPLHRCIYAVRPTGTNNDTALVWMKMNQTLLFLGAPTHPPNGGWRNHAHISYANLIAGRVVPFQVPPDAMNRRIMNVHEAVNCLETLWYTRVRLVVVGWFLYLAFVALHQRRCMFGVVSPAHKMVAPATYLLNYAGRIVSSVFLQYPYTKITRLLCELSVQRQNLVQLFETDPVTFLYHRPAIGVIVGCELIVRFVAVGLIVGTAFISRGACAITYPLFLTITTWCFVSTIGLTELYCILRRGPAPKNADKAAAPGRSKGLSGVCGRCCSIILSGIAVRLCYIAVVAGVVLVALHYEQEIQRRLFDV
What is the function of this protein?
Glycoprotein that probably modulates membrane fusion events during secondary envelopment of cytoplasmic capsids that bud into specific trans-Golgi network (TGN)-derived membranes.  Also plays a role, together with gB, in virus-induced cell-to-cell fusion (syncytia formation).  Seems to block fusion of virions with infected cell membranes (By similarity).
What are the official names of this protein?
Envelope glycoprotein K, Syncytial protein.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae glycoprotein K family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein. Host endosome membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported with UL20 to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN). Cell surface expression of gK is required for virus-induced cell-to-cell fusion. Probably not present in extracellular virions (By similarity).
Protein: CBID_LISMH
Sequence: MEDFIYYNGKKYRKGYTTGTCAAAAAKACVEMILTQEEVSAVQVTTTGGTILEIPVAYQKFSKDKATAAVQKDGGDDIDATHGMWIFVDVDLTDNAEVVLDGGVGIGRATQKGISVAVGEAAINPAPRKNILATVRESLGENRGAKILVYAPEGEERAKRTMNSNLGIIGGISILGTTGIVTPMSDEGWKKSLSMELEMKRNQGLDQIILVPGNYGDDFVQNTLGFSSGNIVSMSNFVGYMLKETQRLAFKKVLMVGHFGKLVKVSAGIFTTYSKDADARAEILVANLALLGAPLSLLQAVEKCNTTEAAGEFIEEAGFTQVYDVIVQKIKARSERFLKFTKPSVEVDVVTFSTERGLLAATKDIDVLREEWR
What is the function of this protein?
Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
What are the official names of this protein?
Cobalt-precorrin-5B C(1)-methyltransferase, Cobalt-precorrin-6A synthase.
What is the protein family that this protein belongs to?
Belongs to the CbiD family.
Protein: PSRP_ECOHS
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: CHSTC_MOUSE
Sequence: MTKPRLFRLWLVLGSALMILLIIVYWDNVGTAHFYLHTSLSRPHILEPLPTQGLVEENVFTSDVDEFLDTLLSSDAKHNDLSRRKTEQPPVPAPSKPVLSHMEENVRGYDWSTHDAHQNPDRDRQQAERRSLLRDFCANASLAFPTKDRSFDDIPNYELNHLIVDDRHGVIYCYVPKVACTNWKRVMIVLSESLLDRGSPYRDPLDIPREHVHNTSTHLTFNKFWRRYGKFSRHLMKVKLKKYTKFLFVRDPFVRLISAFRSKFELENEEFYRKFAVPMLRLYANHTSLPASVSEAFSAGLKVSFANFIQYLLDPHTEKLAPFNEHWRQVYRLCHPCQIDYDFVGKLETLDEDAAQLLRFLKVDSQLHFPPSYRNRTASSWEEDWFANIPLAWRQQLYKLYEADFVLFGYPKPENLLRD
What is the function of this protein?
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin and desulfated dermatan sulfate.  Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices.  Activity toward partially desulfated dermatan sulfate is however lower.  Does not form 4, 6-di-O-sulfated GalNAc when chondroitin sulfate C is used as an acceptor (By similarity).
What are the official names of this protein?
Carbohydrate sulfotransferase 12, Chondroitin 4-O-sulfotransferase 2, Chondroitin 4-sulfotransferase 2, C4ST-2, C4ST2.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 2 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: RL18_SACD2
Sequence: MNAKKQSRIRRARRARAKMKELGVSRLCVNRTPRHIYAQVISAEGDRVVASASTLDKDLRSGSTGNRDAASAVGKLIAERAKAAGVSTVAFDRSGFKYHGRVKALADAAREGGLEF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CMT3_MAIZE
Sequence: MAPSSPSSARPTRASGRKRSAMAEEIHQNQEEEEEVVAASTAKRRRKAASSGKKPKPTPKQAKPAVAGMKKKGETEKTEPVVDDVCAEEPDEEELAMGEEEAEAEEQAMQEVVAAVAAGSPGKKRVGRRSAAASGDHVPEFIGSPVAAAEAHSNWPKRYERSTAANKPEEDDELKARCHYRSAKVDNIVYCLGDDVYVKAGENEADYIGRITEFFEGTDRCHYFTCRWFFRAEDTVINSLVSINVDGHKHDPRRVFLSEEKNDNVLDCIISKVKIVHVDPNMDPKAKAQLIEHCDLYYDMSYSVAYSTFANISSENGQSGSETASGISSDDAGLETSSNMPERTATLLDLYSGCGGMSTGLCLGAALSGLKLETRWAVDLNSFACQSLKYNHPQTEVRNEKADEFLALLKEWAVLCEKYVHQDVDSNLAGSEDQEDADTLDKDEFVVQKLIGIRYDGTGRKKGVYFKVQWEGYGPEEDTWEPIDNLSDCPLKIREFVQEGRKRKILPLPGDVDVICGGPPCQGISGFNRFRNRDEPLKDEKNKQMVTFMDIVAYLKPKYVLMENVVDILKFADGYLGKYALSCLVAMKYQARLGMMVAGCYGLPQFRMRVFLWGALSSMVLPKYPLPTYDVVVRGGAPNAFSQCMVAYDETQRPSLKKALLLGDAFSDLPKVENHQPNDVMEYGGSPKTEFQRYIRLGRKDMLDWSFGEEAGPDEGKLLDHQPLRLNNDDYERVKQIPVKKGANFRDLKGVKVGANNVVEWDPEVERVYLSSGKPLVPDYAMSFIKGKSLKPFGRLWWDETVPTVVTRAEPHNQVILHPTQARVLTIRENARLQGFPDYYRLFGPIKEKYIQVGNAVAVPVARALGYCLGQAYLGESDGSQPLYQLPASFTSVGRTAVQANAVSVGTPAGEVVEQ
What is the function of this protein?
May be involved in the CpXpG methylation and in gene silencing.
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase 3, Chromomethylase 3, DNA methyltransferase 105.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSB_COXBU
Sequence: MEFRVIIPARFDSTRLPGKALVDIAGKPMIQHVYESAIKSGAEEVVIATDDKRIRQVAEDFGAVVCMTSSDHQSGTERIAEAAVALGFEDDEIIVCLQGDEPLIPPDAIRKLAEDLDEHDNVKVASLCTPITEVDELFNPHSTKVVLNRRNYALYFSHAPIPWGRDTFSDKENLQLNGSHYRHVGIYAYRVGFLEEYLSWDACPAEKMEALEQLRILWHGGRIHMVVAKSKCPPGVDTEEDLERVRAYF
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVB_METAO
Sequence: MNGAEAMIKALEAEKVEILFGYPGGALLPFYDALHHSDLIHLLTRHEQAAAHAADGYARASGKVGVCIGTSGPGATNLVTGVATAHSDSSPMVALTGQVPTKLIGNDAFQEIDALGLFMPIVKHNFQIQKTCQIPEIFRSAFEIAQTGRPGPVHIDLPKDVQELELDIDKHPIPSKVKLIGYNPTTIGHPRQIKKAIKLIASAKRPIILAGGGVLLSGANEELLKLVELLNIPVCTTLMGKGCISENHPLALGMVGMHGTKPANYCLSESDVLISIGCRFSDRITGDIKSFATNAKIIHIDIDPAEIGKNVNVDVPIVGDAKLILKEVIKQLDYIINKDSKENNDKENISQWIENVNSLKKSSIPVMDYDDIPIKPQKIVKELMAVIDDLNINKNTIITTDVGQNQMWMAHYFKTQTPRSFLSSGGLGTMGFGFPSAIGAKVAKPDSKVICITGDGGFMMNCQELGTIAEYNIPVVICIFDNRTLGMVYQWQNLFYGKRQCSVNFGGAPDFIKLAESYGIKARRIESPNEINEALKEAINCDEPYLLDFAIDPSSALSMVPPGAKLTNIIDAVQEHPNEKIVCFDEIKRRYMENKRNRK
What are the official names of this protein?
Probable acetolactate synthase large subunit, AHAS, Acetohydroxy-acid synthase large subunit, ALS.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: GREA_LEGPH
Sequence: MSKHPMTVEGAEALKAELHRLKFVDRPRIVEAIATARAHGDLKENAEYHAAREQQSFNEGRIQELEAKLSHAQIIDISKLPNNGKVIFGSTVTICHVATGSELTYKIVGEDEADIKLNKISYSSPIARALIGKELDDAVTVETPGGMVEYEIIQVQYIVE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: HNRDL_MOUSE
Sequence: MEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY
What is the function of this protein?
Acts as a transcriptional regulator.  Promotes transcription repression (By similarity).  Promotes transcription activation in differentiated myotubes.  Binds to double- and single-stranded DNA sequences (By similarity).  Binds to the transcription suppressor CATR sequence of the COX5B promoter.  Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs (By similarity).  Binds both to nuclear and cytoplasmic poly(A) mRNAs (By similarity).  Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers (By similarity).  Binds to the 5'-ACUAGC-3' RNA consensus sequence (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein D-like, hnRNP D-like, hnRNP DL, JKT41-binding protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1- dependent manner.