PharMolix/UniProtQA huggingface dataset:
Protein: LFTR_ECOLU
Sequence: MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WRK46_ARATH
Sequence: MMMEEKLVINELELGKELANRLMNNLKHTSSVDSNKTLISDILRIYQNAIFMLSFNQDKNILKRSLEIDGKDSKNVFKKRKVSEKNTEKVKVFVATEQENGSIDDGHCWRKYGQKEIHGSKNPRAYYRCTHRFTQDCLAVKQVQKSDTDPSLFEVKYLGNHTCNNITSPKTTTNFSVSLTNTNIFEGNRVHVTEQSEDMKPTKSEEVMISLEDLENKKNIFRTFSFSNHEIENGVWKSNLFLGNFVEDLSPATSGSAITSEVLSAPAAVENSETADSYFSSLDNIIDFGQDWLWS
What is the function of this protein?
Transcription factor involved in the regulation of osmotic stress responses and stomatal movement (PubMed:24773321).  Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity).  Positive regulator of EDS1-dependent defense against E. amylovora (PubMed:22316300).  Together with WRKY70 and WRKY53, promotes resistance to P. syringae, probably by enhancing salicylic acid (SA)- dependent genes.  Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1. 2 (PubMed:22325892).  Together with WRKY54 and WRKY70, promotes brassinosteroid (BR)-regulated plant growth but prevent drought response by modulating gene expression (PubMed:28576847).
What are the official names of this protein?
Probable WRKY transcription factor 46, WRKY DNA-binding protein 46.
What is the protein family that this protein belongs to?
Belongs to the WRKY group III family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS20_PROMA
Sequence: MANNNSAKKRIQIAERNRIQNRTYKSAMRTLMKRCFEACGAYSEKPSEDAKKDIQNSMNDAFSKIDKAVKTGVLHRNTGANQKSRLTSVVKKTIEPVVK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RK2_NANDO
Sequence: MAIHLYKTSTPSTRNGTVGSQVKSNPRNNLIYGQRRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNEKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPISMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLKLPSGEVRLISKNCSATVGQVGNVGVNQKSLGRAGSKRWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDSLILRRRSK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SERC_SHIFL
Sequence: MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAIDETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_SYNAS
Sequence: MLKAIVTGGGGKMGARIISLLEEEGGMQLTGVVEKKDHPAAGKDIGEFLGSGKRGIVIQSDLGFCIAGGDVIIDFTSHEASMRHMEMAAEHKRPIVIGSTGFSADEMDRIRKFAQNVPCVLAPNMSVGVNVMFKLLKIVAETLGDDYDVEILEVHHRLKKDAPSGTALKMAQVVAEALGRELDEVGIYERKGLIGERSKKEIGIQALRAGDIVGEHTVIFGAVGERLELIHRAHSRDNFARGAIRAAKWVVRQEPGLYDMQDVLGFRS
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SLX9_MOUSE
Sequence: MGKVRALRARVHRAAVRPDGDSAPGPVPRAVEPALPQSPAGGAGAKDWTFVHNDIFARTQIDPSALVQRLELDQRSVVSLKRGAEPKAILPKKEKLKLRRERWLQKIEAIKLAEQKLREERKRKAMVVVGDLHPLRDALPELQELEAGRQRQQARRRVTSKPRPVELSRMTTVQRQQLLEEERTRFQKLLASPTYRASPLLAIGQQLAHQMQLEGGKQL
What is the function of this protein?
May be involved in ribosome biogenesis.
What are the official names of this protein?
Ribosome biogenesis protein SLX9 homolog.
What is the protein family that this protein belongs to?
Belongs to the SLX9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL6_SALPK
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNALTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVVNLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: RSMA_FRATH
Sequence: MQYKTKAKKSLGQNFLQDENIIRKIVQLANIKKHDIVVEIGPGLGALTRYLLSSSNNVSVVEFDASVIDTLIANCQKYGTPHIYNQDFLKFDISSLENSSNQKIKLIGNLPYNISSPILFKVIKDSDKIVDAHFMLQKEVVERIVSLPNSKSYGRLSVILQYHFDCSMILKIPPEVFYPQPKVDSAILRLKPKNSKELLKNYNFFEEIVKQSFAQRRKTLHNNLKSILKERKIDPSTLPVDTNLRAENLSVGDFVSLANFLS
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KVD29_HUMAN
Sequence: MRLPAQLLGLLMLWIPGSSADIVMTQTPLSLSVTPGQPASISCKSSQSLLHSDGKTYLYWYLQKPGQPPQLLIYEVSNRFSGVPDRFSGSGSGTDFTLKISRVEAEDVGVYYCMQSIQLP
What is the function of this protein?
V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin kappa variable 2D-29.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: FANCC_BOVIN
Sequence: MAEDSAGLPSNYQFWMQKLSVWTQASTLETQRDICLHLPQFQEFLRRMYETLKEMDSNAIIERFPTICQLLAKSCWSPFILAYDESPKILIWCLCCLIKKDPQNSRESKLNSWTRRLLSHIVSTSRFDIKEVGLFNQVLGYAPTDYYPGLLKNMVLSLVSELRENHLNGFSSQRRCPERVRSLSRDRVPLLTLPDFEPLVEALLTYHGHEPQEVLCPEFFDAVNEASLLKKISLPTSAILCLWLRHLPSLENTMLHLLEKLISSERNSLRRIKCFMKDSLRPEAAACHPAIFRVVDEIFRSALLETDGAPEVLAGLQVFTRCFVEALEKENKQLKFALKTYFPYASPALVMVLLQHPKDIPQGLWHQSLKHISEMLKEIVEDHGSYGGPFESWFLFVHFGGWADITAEQLLMSEAEAEPPEALLWLLAFSCSPGAGHQQRARTMVEVKTVLGCLTKLFRSPALSARDLQAAAGENLGGDPRPPACQQLVRRLLLHFLLWAPGGHTIAREVITLMAQTDAIMNEIIGFLDYTLYRWDHLCVEAHRSRKLARELLTELREQALPGQVNQ
What is the function of this protein?
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function.  May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1 (By similarity).
What are the official names of this protein?
Fanconi anemia group C protein homolog, Protein FACC.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Protein: LEU1_ECOL5
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: GRPE_OCEIH
Sequence: MNEKDNQTTSEPENEQEIIDVNDSGEQPEENETEQPQEEAVENDEIAKLQQEKDETYNRLVRLQAEFDNYKRRTLKEREADRKYKSQDLITELLPAIDNFERALQVEVTEENKSIIDGIMMVYRQLQEALTSQGVEPIKTEGEVFDPNLHHAVMQIEDENMDSNTVVEELQKGYQLKDRVIRPAMVKVNK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_DESVH
Sequence: MTDAKRAQKLDLSLDHKVADMSLADYGRKDLQLSEREMPGLMELIRKYGGTKPLKGLKVTGSLHMTIQTAMLIRTLYELGADIRWASCNIFSTQDHAAAAIAASGMAKVFAWKGETLEDYWWCTEMALTWPDGSGPDLLVDDGGDATLFIHKGVEVENDPSLLKKAYDNKEFQIIMDRLALAYEQDPGRWQRVAAKVRGVSEETTTGVHRLYQLEQEGKLLFPAINVNDAVTKSKFDNLYGCRESLADGIKRATDVMVAGKVVVVAGYGDVGKGCAQSMRGFGARVLVTEIDPICALQAAMEGYEVTTMEEAVRTGDIFVTATGNCNVITGAHMEAMKDEAIVCNIGHFDNEIDMHYLENTEGCVCLNIKPQVDKWTLRSGRSIIVLAEGRLVNLGCATGHPSFVMSASFTNQTLAQIELATNPDLERKVYTLPKKLDEEVARLHLDRLGVKLTRLSKDQADYIGVSPEGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8E_SULIN
Sequence: MGFYQGPDNRKITGGLKGKHRDKRKYEIGNPSTLTTLSAEDIRIKDRTLGGNFKVRLKYTTTANVLDPATNTAKKVKILEVLETPANKELARRGIIIRGAKIRTEAGLAVVTSRPGQDGVINAVLLKNESQGS
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: NFUA_PSEMY
Sequence: MSAITITQAAEDYLAELLSKQDTPGIGIRVFITQPGTPYAETCIAYCKPGEQKPEDTPVGLASFTAWIDAVSEPFLEDAVVDYATDRMGGQLTIKAPNAKVPMVNEDSPLNERINYYLQTEINPGLASHGGQVSLVDVVEEGIAVLRFGGGCQGCGQADYTLKEGIEKTLLERIPELKGVRDVTDHSNRENAYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: GAR1_DROME
Sequence: MGFGKPRGGGGGGGRGFGGGGGGGGRGFGGGGGGRGGGGGRGGGGGFGRGGGGRGGGRGAFDTGPPERVIPLGNYVYSCQNDLVCKVDIQDVPYFNAPIFLENKEQVGKIDEIFGTVRDYSVSIKLSDNVYANSFKPNQKLFIDPGKLLPIARFLPKPPQPKGAKKAFTNNRGGGGGGGGFGGRGGGRGGGGRGGGGGRGGGGFRGGAGRNGGGGGGGGFNRGRGGGGGGGGGRGRW
What is the function of this protein?
Required for ribosome biogenesis.  Part of a complex which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
What are the official names of this protein?
Probable H/ACA ribonucleoprotein complex subunit 1, GCR 101 snRNP, Nucleolar protein family A member 1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: XYN4_ASPNG
Sequence: MKVTAAFAGLLVTAFAPPVPEPVLVSRSAGINYVQNYNGNLGDFTYDESAGTFSMYWEDGVSSDFVVGLGWTTGSSNAITYSAEYSASGSSSYLAVYGWVNLSQAEYYIVEDYGDYNPCSSATSLGTEYSDGSTYQVCTDTRTNEPSITGTSTFTQYFSVRESTRTSGTVTVAIHFNFWAQHGFGNSDFNYQVMAVEAWSGACSASVTISS
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase 4, Xylanase 4, 1,4-beta-D-xylan xylanohydrolase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 11 (cellulase G) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYG1A_XENLA
Sequence: MKYILVTGGVISGIGKGVIASSIGTILKSSNLHVTSIKIDPYINIDAGTFSPYEHGEVFVLDDGGEVDLDLGNYERFLDIRLTKDNNLTTGKIYQSVINKERKGDYLGKTVQVVPHITDAIQEWVMRQALIPVDEDGIEPEVCVIELGGTVGDIESMPFVEAFRQFQFKVRRENFCNIHVSLVPQPSATGEQKTKPTQNSVRELRGLGLSPDLVVCRCSTPLDTSVKEKISMFCHVEPQQVICVHDVSSIYRVPLLLEEQGVVDYFRQRLDLPIGRQPRRLLMKWKEMADRYERLLESCSIALVGKYTKFSDSYASVIKALEHSALAINHRLEIKYIDSADLEQETLQEEPVRYHEAWQKLCSSEGILVPGGFGVRGTEGKIQAIAWARKQKKPFLGVCLGMQLAVVEFARDVLGWTDANSTEFNPKTSHPVVIDMPEHNPGQMGGTMRLGKRRTIFHSQNSIMKKLYGGHEYVEERHRHRYEVNPELRRELEVRGLKFVGQDTEGERMEIVELEDHPYFVGVQYHPEFLSRPIKPSPPYFGLLLASVGRLSQYIERGCRLSPRDTYSDRSENSSPDAEIAELKLPMIDHD
What is the function of this protein?
This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids.  Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen.
What are the official names of this protein?
CTP synthase 1-A, CTP synthetase 1-A, UTP--ammonia ligase 1-A.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: HLDE_SHEPA
Sequence: MKISLPAFEKAKVLVVGDVMLDRYWAGPTARISPEAPVPVVKVEQLEDRPGGAANVAINIATLGGSASLAGIVGVDETADALTVGVRALGVEPNWHKVADKPTITKLRVMSRNQQLLRLDFEESYSQAESDALLAQSLSELDKVDVAVLSDYAKGALISPQSFIEAANAKGVKVLVDPKGSDFSKYRGAYLLTPNMSEFEVVVGKVESEADLVAKAQGLLQAFDLTAMLVTRSEKGMTLITKDQPELHIPTVAREVYDVTGAGDTVISALATAIAAGSDLPQACAIANTAAGIVVAKLGTSTVTRLELIEALSLSHGESGFGAVSEDQLAYALEQAKLRGERVVMTNGCFDILHAGHVSYLQQARALGDRLIVAVNTDASVKRLKGEGRPVNSEDRRMTVLAALASVDWVVPFSEDTPQRIISRLLPDLLVKGGDYKVEDIAGGSEVMAAGGQVKVLGFEDGISTTAIIQNIMANQ
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: MT_CARMA
Sequence: MPDPCCIDKCECKEGGCKAGCKCTSCRCTPCEKCSSGCKCTTKEDCCKTCTKPCSCCP
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.  Class I MTS in marine crustacea are involved in the sequestration of elevated levels of heavy-metal ions.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 3 family.
Protein: DTX10_ARATH
Sequence: MQDAERTTNDPVDRIEKVTWRDLQDGSFTAELKRLICFAAPMAAVVIIQFMIQIISMVMVGHLGRLSLASASFAVSFCNVTGFSFIIGLSCALDTLSGQAYGAKLYRKLGVQAYTAMFCLTLVCLPLSLLWFNMGKLIVILGQDPAIAHEAGRYAAWLIPGLFAYAVLQPLIRYFKNQSLITPLLVTSSVVFCIHVPLCWLLVYKSGLGHIGGALALSLSYWLYAIFLGSFMYYSSACSETRAPLTMEIFEGVREFIKYALPSAAMLCLEWWSYELIILLSGLLPNPQLETSVLSICFETLSITYSIPLAIAAAASTRISNELGAGNSRAAHIVVYAAMSLAVMDALMVSMSLLAGRHVFGHVFSSDKKTIEYVAKMAPLVSISIILDSLQGVLSGVASGCGWQHIGAYINFGAFYLWGIPIAASLAFWVHLKGVGLWIGILAGAVLQTLLLALVTGCTNWKTQAREARERMAVAHESELTESELPI
What are the official names of this protein?
Protein DETOXIFICATION 10, AtDTX10, Multidrug and toxic compound extrusion protein 10, MATE protein 10.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MURE_LEPBJ
Sequence: MKMKLTNLLHEFPELKLGSLPSGKNPDSVPIEYIQSDSRKTNPEDIFCVPESIGTKKGEFISNTKASVILLHRSSNISIDSSKIVLECEEDPEQLQGRIASFLLGHPSKTLEIVAVTGTNGKTSLTNILFALAKDQGKICGLIGTIGVKFGDRSIDTGYTTPDASSLNLILKQMKDEGVTTVFMEASSHGLKLGRIGGISLKAGVFTNLTQDHLDFHSDMEDYFESKFRLFEILDVSKSPFAVLDYSSPGGNELHRKIRNNLPDLPIKALDGIGGEYKVSNPFLTLQGTSYVLSLPGNRSQTISTNLLGSFNVRNTALAFLTGLGLGLDPKGMFSSLKEIPQIPGRFQIVYSKDRSRMAVVDYAHTPDALENIIRSVRNSRPKRLITLFGCGGDRDKTKRPKMARIAEELSDQVILTSDNPRSEKPEAILDEIQSGFSPGFTPLLREVDRARAISEGVGILPEGGCLLVAGKGHEEYQIIGKEKRHFSDVEEVRKAFGLF
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_WOLSU
Sequence: MLLCDIGNTYLHFYQEGKVWKELPRRLKAGMEVQEVYYISVNPPSARRLLEVYPHAIDLAPHMVLDTAYKGLGVDRMAACKGIEDGVVVDAGSAITVDVMQNQVHLGGFIMPGIASFSSMLKSISPALEKELNLSVELSALPQNTRDALSYGAIKAIVMMIQNSCKNKRLFFTGGDGKYLARFFENAIHDNSIVFKGMLKTLEEMKEGKR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPIA_SPHAL
Sequence: MSNFVAEKSIAAVRAVDEVRDGMLVGLGTGSTAAYAVKSLSERIKHGLRITAVATSQATEALALRLAVPLVPFQQLSAVDLTIDGADEIDDRFQAIKGGGGALLREKITESASTRVIIIADSSKLVAQLGKFPLPVEVVPFATEFVRARLSALGARVTVREAGGTPFLTDQGNYILDAALDEIPRPREIAAAITTIPGVLEHGLFLDEIDTIMIARGDMVEVRHRGEA
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PSAM_NEOYE
Sequence: MIDDSQIFVALLFALVSAVLAIRLGKELYQ
What are the official names of this protein?
Photosystem I reaction center subunit XII, PSI-M.
What is the protein family that this protein belongs to?
Belongs to the PsaM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PG204_VACCW
Sequence: MTMKMMVHIYFVSLLLLLFHSYAIDIENEITEFFNKMRDTLPAKDSKWLNPACMFGGTMNDIAALGEPFSAKCPPIEDSLLSHRYKDYVVKWERLEKNRRRQVSNKRVKHGDLWIANYTSKFSNRRYLCTVTTKNGDCVQGIVRSHIRKPPSCIPKTYELGTHDKYGIDLYCGILYAKHYNNITWYKDNKEINIDDIKYSQTGKELIIHNPELEDSGRYDCYVHYDDVRIKNDIVVSRCKILTVIPSQDHRFKLILDPKINVTIGEPANITCTAVSTSLLIDDVLIEWENPSGWLIGFDFDVYSVLTSRGGITEATLYFENVTEEYIGNTYKCRGHNYYFEKTLTTTVVLE
What is the function of this protein?
Counteracts the antiviral effects of host IFN-alpha/beta and key IFN-inducible proteins involved in viral RNA degradation suxh as host OAS1 (PubMed:28877647).  Acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.
What are the official names of this protein?
Soluble interferon alpha/beta receptor OPG204, B18.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
Protein: NEC2_EBVB9
Sequence: MASPEERLLDELNNVIVSFLCDSGSLEVERCSGAHVFSRGSSQPLCTVKLRHGQIYHLEFVYKFLAFKLKNCNYPSSPVFVISNNGLATTLRCFLHEPSGLRSGQSGPCLGLSTDVDLPKNSIIMLGQDDFIKFKSPLVFPAELDLLKSMVVCRAYITEHRTTMQFLVFQAANAQKASRVMDMISDMSQQLSRSGQVEDTGARVTGGGGPRPGVTHSGCLGDSHVRGRGGWDLDNFSEAETEDEASYAPWRDKDSWSESEAAPWKKELVRHPIRRHRTRETRRMRGSHSRVEHVPPETRETVVGGAWRYSWRATPYLARVLAVTAVALLLMFLRWT
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network (By similarity).  Inhibits host IKBKE and IRF3, thereby impairing type I IFN signaling (PubMed:33391252).
What are the official names of this protein?
Nuclear egress protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC2 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane; Single-pass membrane protein. Note=Localizes also at the transient membrane of perinuclear virions.