PharMolix/UniProtQA huggingface dataset:
Protein: RPB7_BOVIN
Sequence: MFYHISLEHEILLHPRYFGPNLLNTVKQKLFTEVEGTCTGKYGFVIAVTTIDNIGAGVIQPGRGFVLYPVKYKAIVFRPFKGEVVDAVVTQVNKVGLFTEIGPMSCFISRHSIPSEMEFDPNSNPPCYKTMDEDIVIQQDDEIRLKIVGTRVDKNDIFAIGSLMDDYLGLVS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element.  The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft.  The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.  Binds RNA (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB7, RNA polymerase II subunit B7, DNA-directed RNA polymerase II subunit G.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
Protein: UVRB_TREDE
Sequence: MKQFKLISDYKPSGDQGEAIKALSDGIIAGDKFQTLKGVTGSGKTFTMANIIQAVQKPTLIISHNKTLAAQLYREFKTFFPENAVEYFVSYYDYYQPEAYVPARDLYIEKDASINDEIDRLRLSATFSLMERRDVIVVSTVSCIYGLGLPESWRDLRITIEKGENIEIEKLKKQLISLQYERNDAVLERGRFRVKGDVMEIFPAYMEDAYRLEFDWEEIVRIRKFNPISGEVIQEYEELSIYPAKHFVMPEDAIPNALERIKKELEERLNVLNKEGKLLEAERLKTRTEYDIEMLSEMGYCPGIENYSAPIANRKPGEPPATLFHYFPDDFLLFMDESHVTFPQVGAMYEGDRSRKQNLVDFGFRLPCALDNRPLKIDEFEKMLNQAVFVSATPGPKEIKYSTRIVEQVIRPTGLLDPIIEIHKSEGQMEHIYGEVKKRIALNERSLILTLTKKMAEDLTDYLTGLGLKVKYIHSEVETIERVEILKGLRAGEFDVLIGINLLREGIDLPEVSFIGILDADKIGFLRSTTSLIQIVGRAARNENGKVVMYADRISDAMKETIEETNRRRAIQEAYNKEHGITPKTIKKAIEDILTRENEIKKEAALAEAGPLINSLNILNPADRKKLIKKLEAQMAEYADMLMFEEAAVIRDKIEEVKRIGS
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_BACCQ
Sequence: MLMPKRVKYRREHRGKMRGRAKGGTEVAFGEFGLQAQAASWITNRQIEAARRAMTRYMKRGGKVWIKIFPSKPYTAKPLEVRMGSGKGAPEGWVAVVKPGKIMFEIAGVSEEVAREALRLAAHKLPVKCKFVKREENGGESNEN
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TSAC_SALPB
Sequence: MNNNLPTGSIAAAVDLLNKENVIAYPTEAVFGVGCDPDSETAVTRLLALKQRPVDKGLILIAASFEQLKPYIDDSILTAAQRKAVFDCWPGPVTFVFPAPATTPRWLTGRFDSLAVRVTNHPLVVALCNAYGKPLVSTSANLSGLPPCRTVEEVRAQFGDDFPVVEGATGGRLNPSEIRDALTGELFRQG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRE_LACJO
Sequence: MHKDQIISQLIKEKIITISPDKPFTYASGMLSPIYTDLRLTVSYPDLRDMIASDLSNLIAAEFPQATIIGGVATAGIPHAALVAEKLHLPMIYVRPKPKDHGKGRQIEGRFSENDQIVLIDDLITTGGSVLNAVKATEKDGGKVAGVASIFTYYLPDAKENFKEANVKYTPLLSYPELLKKENESGHITSDQYDILKTWHEDPWAWGKKFNS
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: TSR1_DICDI
Sequence: MSEHRHRSGDLHQQNKGFKGGKHDSKGAIKRRAQGKIETNGARQSIKNLAIVNNKDAMRQKHQKLVKSKKNELLERKRLGLPDQVAPRVVTIIKLSESCNTKKVKEMLLQKFKLNINTGEMEMDNEETLNNKNNNNDNFTTISLTSKVRMMLLECQTMAYDQVIEFCKLSDIILFVIDANQAKLNSEAERIFTIVKAQSVPTVIEIIQNLDQTPIKKRNELKKSIQSVFHFHFPNEPKVLPMDTNDECSQVLRYIENIHVNEIIWRKVRPYMLIEKSSYIPETKVVTIDGFIRGNNLSAKQIIHIPDYGDFQIEKIELIDDPHIRKKSYYTNNNNNNSNNNNTGGGEMEQDKKINILDKVDQKDKDTLQTWNVPDPMDNEQALPTAEEMKEIEANKKKKLVPKGTSGYQSSWYLDNESDEEEENFENEDLDMNQEEMGQDKEEEMGEEEEMGEEEEEEEEGQEELEEVKESNKWKGIKHKSQITDELLKDSDDEDDDENKEEQSEDEDEDERKQLQQDEILYPDEVDTPGNVPSRIRFSKFRGLKSFRSSPWDVKENLPIDYAKIFQFHSFNQSMRASIAILDNAPAKPDMYVRIHLVNGPKQLVERNTTAITTKPEVAVGLYRYENKISLLHFSVEKHKSYEETVRSKEEVYFHFGWRKFSTSPIYSISSPNCDKQKFEKFLLPARNTMATIYGPITYPPAPLLIFNGKDCNELVATGYLSSVNPDRIICKRIILTGVIAKSISKKFVTVKDMFYYPEDINWFKKVELYTKMGRVGHIKEPLGTHGRMKCQFDGTMNQQDTVCMNLYKRVYPKWIKDDSSLLKLE
What is the function of this protein?
Required during maturation of the 40S ribosomal subunit in the nucleolus.
What are the official names of this protein?
Pre-rRNA-processing protein TSR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: STE7_CANAW
Sequence: MTRTTRIDTQEATKHKDLPPVPSPLSLSSNPNPECLMESKSLGRKNFKKLSLDASPVKSTSGSLRSSDMMSIKEPTSLRQKRQRPPPILHLPTASSSATSTPTSNITGSSSASSIQFAQKSPGSGVIVSQTLSRPSSAGGIPSSGYSSLNVNQSNRNVDPDNVVSTDMILNQISNLDLTSMNHHRQHYQNSHHHLPTTNRKRQTVISSISPTKSSAASSPLEPQIQSLPASSQSPIATTSALKLNNKDLLTLKQLGSGNSGSVSKILHIPTQKTMAKKIIHIDSKSVIQTQIIRELRILHECHSPYIIEFYGACLNNNNTIVICMEYCNCGSLDKILPLCENKQFPTFVLKKLSFAILSGLTYLYTTHKIIHRDIKPNNVLMTHKGEFKLCDFGVSRELTNSLAMADTFVGTSMYMSPERIQGLDYGVKSDVWSTGLMLIELASGVPVWSEDDNNNDDDEDDEDDAYVRQGSIAAERNGQNSPSRSRKNKQKGNGYNSYNGPEGILDLLQRIVNEDAPTLTNKINPVTKLPYDKYLCQFIDLCLIKDDSVRKTPWQLLEDKEHFFKGVEEGVYDKEHKSWAKKIRKCKV
What are the official names of this protein?
Serine/threonine-protein kinase STE7 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
Protein: RS4E_METST
Sequence: MANMGSRKHLKRFKAPKMWPIHKKEEVWTTKTSAGPHALEESIPLVMVLRDILGLAANSREAKIILNNSDVLVDGIPRKNHRFPVGFMDVISIPKINKTFRVLQDYKGRLVLKEIEEKDSTFKLVKILGKTTIKGGKTQLNLEGGRNIIADDDYKTGDVLLLNIPEQKISDSIKFEEGALGLITGGKHISEVGKIDEIKITQSSKSNTVLMETEEGSFLTLARYVFVVGQDKPVISLVGDN
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: ILVE_STAAN
Sequence: MSQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDADKGWHDLKIVPYGPIEISPAAQGVHYGQSVFEGLKAYKRDGEVALFRPEENFKRLNNSLARLEMPQVDEAELLEGLKQLVDIERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLIILSPSGAYYGGETLKPTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQVLWLDGVEQKYIEEVGSMNIFFVENGKVITPELNGSILPGITRKSIIELAKNLGYEVEERRVSIDELFESYDKGELTEVFGSGTAAVISPVGTLRYEDREIVINNNETGEITQKLYDVYTGIQNGTLEDKNGWRVVVPKY
What is the function of this protein?
Acts on leucine, isoleucine and valine.
What are the official names of this protein?
Probable branched-chain-amino-acid aminotransferase, BCAT.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: OEP21_ORYSJ
Sequence: METSLRLRGGGSRPQSKSQEGLRIHAKEKLPIASNALLQAHGEIHAATGAPTYLALLFRNFYPRLSANLGLGLAIHFRNNQPLPLAWDNFSYTLRASKAIIPFPSNALLGINLKGRLLADKYFNPTARTAAVELAWTILDLKRGQDVRLKLGYQLLHKMPYFQLRENNWTFNAYMDGKWDVRFDL
What is the function of this protein?
Voltage-dependent rectifying anion channel that facilitates the translocation between chloroplast and cytoplasm of phosphorylated carbohydrates such as triosephosphate, 3-phosphoglycerate and inorganic phosphate (Pi) depending of ATP to triosephosphate ratio in the plastidial intermembrane space; in high triosephosphate/ATP conditions (e. g.  photosynthesis), export of triosphosphate from chloroplast (outward rectifying channels), but in high ATP/triosephosphate conditions (e. g.  dark phase), import of phosphosolutes (inward rectifying channels) (By similarity).
What are the official names of this protein?
Outer envelope pore protein 21, chloroplastic, Chloroplastic outer envelope pore protein of 21 kDa.
What is the protein family that this protein belongs to?
Belongs to the plastid outer envelope porin OEP21 (TC 1.B.29) family.
What are the subcellular locations of this protein?
Plastid, etioplast membrane; Multi- pass membrane protein. Plastid, chloroplast outer membrane; Multi-pass membrane protein. Note=Present in non-green root plastids.
Protein: PHEA_POLUR
Sequence: MKSVITTTISAADAAGRYPSTSDLQSVQGNIQRAAARLEAAEKLGSNHEAVVKEAGDACFSKYGYNKNPGEAGENQEKINKCYRDIDHYMRLINYTLVVGGTGPLDEWGIAGAREVYRTLNLPSAAYIAAFVFTRDRLCIPRDMSAQAGVEFCTALDYLINSLS
What is the function of this protein?
Light-harvesting photosynthetic tetrapyrrole chromophore-protein from the phycobiliprotein complex.
What are the official names of this protein?
R-phycoerythrin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Forms the periphery of the phycobilisome rod.
Protein: HIPL1_ARATH
Sequence: MKLHQFLVFLFLFLSCFALSSWALPLCSDSRAPSEVNSTLSFCPYKGKTCCNTMKDTSLMKQFQAMNISDKGCASVVKSILCANCDPFSSDLFRDNSDQQSVPILCNSTSSANSTENFCSETWETCQNVSISGSLFAASLQGRAGAPSNKNASKLADLWQSKTDFCSAFGGASSNETVCFSGEPVALNDNDTTPDKPPSGICLEKIGNGSYLNMVPHPDGSNRAFFSTQPGIVFLAGIPDQDSGGVLDVDPSSPFVDMTDEIHFDTEFGMMGMAFHPKFAQNGRFFASFNCDKSKWPGCTGRCSCNSDVNCDPSKLTPDSGSQPCQYQTVIAEYTANSTSSDPSKAKNAKPTEVRRIFTMGLPFTSHHAGQILFGPDGYLYFMMGDGGGGADPYNFAQNKKSLLGKIMRLDVDNIPSASEISKMGLWGNYSIPKDNPFREDKELEPEIWAVGLRNPWRCSFDSSRPSYFMCADVGQDTYEEVDLISKGGNYGWRVYEGPDLFHPESSPGGNTSVKSLNPIFPVMGYNHSEVDSSGKSASITGGYFYRSETDPCIAGRYVYADLYGNGVWAGIETPANSGSFVTKRTTFSCASDSPMKCSDSPGTSGLSLGYVFSFGEDNNKDIYLLTSNGVYRVVRPSRCNLTCSKENSTARRNPGTSSSPSSSSSSCYKHINGFHGSLVVLFVSLSLILLGLLN
What are the official names of this protein?
HIPL1 protein.
What is the protein family that this protein belongs to?
Belongs to the PQQ oxidoreductase GdhB family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: SYL_PROM1
Sequence: MNNTTSDINDQRYEPREVEAYWQKEWANDDLYRTNTEVNKENTFYALSMFPYPSGSLHMGHVRNYVITDVLARYKRMKGLNVLHPMGWDSFGLPAENAAIERETSPSTWTDKNISQMKDQLDRLGLSIDWSKEVTTCKEDYYKWTQYIFNQLHKNNLAYQKKATVNWDPIDQTVLANEQVDAEGKSWRSGAKVEKKELNQWFLRITSFAEDLNKDLVTLNDWPDRVRVMQKNWIGKSIGAEITFDIKNSDQKITAFTTRIDTVYGVSYLVLASNHPLIDQLISSNDIDKLNDFRQTQEKLSDLERNSDTRQKLGMYLGVDAINPANNKEIPIWIGDYVIMEYGTGAVMGVPAHDSRDYQFAKSYDLPIQYVIKPNIGEDESYLNAEFVDKGVMINSDKFNGIESDIAKTKILEFGSNSNWAKPKITYKLRDWLISRQRYWGCPIPIINCKKCGQVRVPDDDLPVVLPIDIKLTGKGKSPLTTKTEWINTCCPKCGTDAKRETDTMDTFMCSSWYFLRYINPDNCEKPFLKSEIDKWLPVKQYVGGIEHAILHLLYSRFLTKALKRCGLINIDEPFKKLLTQGMVQAVTFKNPNTNKYFSKDQIKDIDNPKDPLTGENIEIIYEKMSKSKYNGVDPSVVIDKYGADTARMFILFKAPPEKDLEWDDSDVEGQYRFIQRLWKFVINTFKLTNNNSRSNIEKEKSKDEEALRLINIAIKEITDDLDNLQFNTAISELMKVVNGLSLIVNYCSNETLNKVISILVKITSPFSPHIAEELWKTIGNTQSIHLQSWPEFDAGAIEQDTFKLMIQINGKVRGSINASKNLSKENLEDLAIKTEAAIKWMDGKEPKRIIVVPNKLVNIVI
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y675_VIBC3
Sequence: METLAELPSPWFVYLVRCANNALYCGITTDVSRRFAQHQKGRGAKALRGKGPLELVWSLPVADGKSAALKLEYRIKALSKSQKEALVAGMARIDQLEIIFQ
What are the official names of this protein?
UPF0213 protein VC0395_0675/VC395_A0575.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: SRA1_RAT
Sequence: MAELYVKPGNKERGWNDPPQFSYGLQTQTGGTKRTPLTKRVAAPQDGSPRAPETSGPPPVDHPPPSSKASRPPPMGSCPASGVDPPSSPVIESETLIEDVLRPLEQALEDCRGHTKQVCDDISRRLALLHEQWDGGKLSVPVKKRMALLVQELLHHQWDTADDIHRSLMVDHVTEVSQWMVGVKRLIAEKRSLSSEENKEEKSTVAPENQTIPGFQPSS
What is the function of this protein?
Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors.  Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2).  Enhances cellular proliferation and differentiation and promotes apoptosis in vivo.  May play a role in tumorigenesis.
What are the official names of this protein?
Steroid receptor RNA activator 1, Steroid receptor RNA activator protein, SRAP.
What is the protein family that this protein belongs to?
Belongs to the SRA1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CHMP7_DICDI
Sequence: MNNDKEINSEKSKRAINHFSNKKEIKNSDRRGILFSKLPSQQLNPDRYDNLMTFWNNSLIDISKSCNILIFTPKLLSTYFTVENVSPIYLPLILNEMIKTKFIVKYEEYIKDYGWSKWVWTKMVVQPFQYYTGLSTPNTETEKNVKFILPEMIKDKAEQLYQHQLKNMNSTTDNIISYINLEKSIKDWYITREELDLLLLVLFRDSKVLILTNNKIKNINNNNNGEDRIGIKFAFDGEKVQPIQETDFGILKLQTTYETLKQQESKLLTDIEEISNTIKESIRIKQKNHALLQLKKKKLLESILEKRATASTNIHEILFSIESAKSNQQIIESLCTGVSTLKKVNQEISVDQVDSILDDYQDAITNQREIDDAMKSGFNSVESLSSADIDEDQLEKELDQMLQDHLTLEKEEKQKQKQIEKEKQQQQQPPTSQFNPNLPIPLKNEEDELLKELESLSVTSNPLPKQDENKQKTSELI
What is the function of this protein?
Plays a role in the endosomal sorting pathway.
What are the official names of this protein?
Charged multivesicular body protein 7.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_CAMJR
Sequence: MINIAIDAMGGDFGEKPIIEGVLKALEAKPFNAILVGNSKILKPLIPKKLEQYIQYEEASEIFSMNGNATDALKNKETTIYKAINLLKEKKVDAVVSAGHSGASMSLATLRLGRLKGISRPAIATLMPNIVNRTLLLDVGANTDCKAENLFQFAIMGEVYAREIMQIQKPRLALLSNGEEECKGNELTKESHQLMKKIPNFIGNAEGRDIFNGEIDVLVCDGFDGNVILKACEGVATAIFQLLKNEVKQSFISKIGALLMKSSFKKLKKHTDWQEYGGAPLLGVNGCVIISHGKSDSRAIKNAIFQAINFSQSHINELIENELGKYNA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ULAD_SALSV
Sequence: MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
3-keto-L-gulonate-6-phosphate decarboxylase UlaD, 3-dehydro-L-gulonate-6-phosphate decarboxylase, KGPDC, L-ascorbate utilization protein D.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: Y1129_STAA3
Sequence: MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEIADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRYIQQLEDLE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein SAUSA300_1129.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: TACAN_BOVIN
Sequence: MHPPPPGPLGDCLRDWEELQQDFHGIQETHRLYRLKLEELTKLQNSCTSSITRQKKRLQELALVLRKCKPSLPSEAEEAARELENQIKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILILISFTCRFLLNSRVTDAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYYQSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGFPFLLLFLGNFFTTLRVVHQKFHNQLHGSKKE
What is the function of this protein?
Ion channel involved in sensing mechanical pain.  Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli.  May also be required for efficient adipogenesis.
What are the official names of this protein?
Ion channel TACAN, Transmembrane protein 120A.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein.
Protein: TRPD_ARTS2
Sequence: MTSQASAQAAGNTWPRLISALINGADLTADNTEWAMDTIMSGEATPSQIAGFLVALRSKGETVDEIAGLVEAMLAHANPVDIAGEKLDIVGTGGDQLNTVNISTMAALVCAGAGAKVVKHGNRASSSSSGSADVLEALGVRLDLPIERVARNAEEAGITFCFAQVFHPSFRHTAVPRRELAIPTAFNFLGPLTNPARVQASAVGVANERMAPLVAGVLAKRGSRGLVFRGSDGLDELTTTGPSTVWEIRNGEVTEQTFDPQALGIRAATVEELRGGDATANAAVVRDVLSGVAGPARDAVLLNAAAGLVAFDVDAEGTLTDRMAAALKRAEESIDSGAAAAVLEKWVALTRG
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: STN1_SCHPO
Sequence: MLENENQLTHQFPTLSRWNPMFISDVHKISFHPHLQRYIGFWMGFPIRWIQIVGYIAAIDIYEGKHVLTVDDCSGMVLRVVFIIQDDFSMSKRAISMSPGNVVCVFGKINSFRSEVELIAQSFEELRDPNDEWKAWQKRMRYKKNLTKISKNHHSIIRTPKKSYFPKDHAKELLKCIRQMCKLNVQAGFTIEELIIYLKAKELHLPLVHIFNVENEIVENCDGNHILALNFSLQTLLQHGRIVRKSNSVYMLVTSKDIIRFVIPLMASGLLEAHKVQSIVRDSNPMFITLPLSAIAKHICQFLLRTKGKWRQAKKYTWVRDNQFV
What is the function of this protein?
Required for telomere maintenance.
What are the official names of this protein?
Protein stn1.
Protein: PFKAM_HORSE
Sequence: MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIREATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAHNLVKLGITNLCVIGGDGSLTGADTFRSEWSDLLSDLQKAGKITAEEATKSNYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIIEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEDHLCRRLSETRTRGSRLNIIIVAEGAIDRNGKPITSESIKDLVVKRLGYDTRVTVLGHVQRGGTPSAFDRILGSRMGVEAVMALLEATPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMAERKFDEAMKLRGRSFMNNWEVYKLLAHIRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNRVLVVHDGFEGLAKGRIEEAGWSYVGGWTGQGGSKLGTKRTLPRKSFEQISANITKFNIQGLIIVGGFEAYTGGLELMEGRKQYDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICMTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQVNVEHLVQKMKTTVKRGLVLRNEKCNENYSTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVTELKEQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSEHAHLEHISRKRSGEAPA
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, muscle type, ATP-PFK, PFK-M, 6-phosphofructokinase type A, Phosphofructo-1-kinase isozyme A, PFK-A, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THOC3_HUMAN
Sequence: MAVPAAAMGPSALGQSGPGSMAPWCSVSSGPSRYVLGMQELFRGHSKTREFLAHSAKVHSVAWSCDGRRLASGSFDKTASVFLLEKDRLVKENNYRGHGDSVDQLCWHPSNPDLFVTASGDKTIRIWDVRTTKCIATVNTKGENINICWSPDGQTIAVGNKDDVVTFIDAKTHRSKAEEQFKFEVNEISWNNDNNMFFLTNGNGCINILSYPELKPVQSINAHPSNCICIKFDPMGKYFATGSADALVSLWDVDELVCVRCFSRLDWPVRTLSFSHDGKMLASASEDHFIDIAEVETGDKLWEVQCESPTFTVAWHPKRPLLAFACDDKDGKYDSSREAGTVKLFGLPNDS
What is the function of this protein?
Required for efficient export of polyadenylated RNA and spliced mRNA.  Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA.  TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.  The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
What are the official names of this protein?
THO complex subunit 3, Tho3, TEX1 homolog, hTREX45.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle.
Protein: EFP_CELJU
Sequence: MKIAQECRAGNVVMIDGSPWVVQKAEYNKSGRNAAVVKMKLKNLLSGINTETVYKADDKFEDILLDRKEVTYSYYADPMYVFMDGEYNQYEVTKEDLGDLLPWIEDGMEDVCDAVFYEGKVISVTAPTSIVREIAYTEPAVRGDTSGKVMKVAKLKNGTELSVAAFVEIGEKIIIDTRTGEYKSRAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_SHEPW
Sequence: MTAQNIDGKAIAQAIRTKLKDKVTARKEAGQRVPGLAVILVGADPASQVYVGSKRRACEELGFISRSYDLDSSTSEDALLSLIDECNEDQSIDGILVQLPLPEHIEESKVIERIRPDKDVDGFHPYNVGRLAQRIPVLRSCTPMGIMTLIQSTGVDTYGLDAVVVGASNIVGRPMSLELLLAGCTTTTCHRFTRNLEQKVRQADLVVVAVGKPGFIPGEWIKPGAIVIDVGINRLESGQLVGDVQFEKAAENASFITPVPGGVGPMTIASLLENTLYACEQYHDHD
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.