PharMolix/UniProtQA huggingface dataset:
Protein: VW5B2_MOUSE
Sequence: MPGLYCPTSWTPLPLTDSCVRAYAKGPCLSLRARLTYHNPQPQPVEGVFVYPLAEAEVVSGFEAEAAGRRVSFQLHSRRRSQAACCRALGPGLGTSTPRRCAQGHLVLNLAQARSTLVLPTGLVAAAGTMTVTLCSSRELPSRPDGVMHVALPTVFTPLAQPNLPGSPRSPGLCDDSPTSCFGVGSPEEERPTWEQPTATPDVFSGPARCPAPYTFSFEMLVTGPCLLAGLESPSHALRADALPHASSAATIRVTLAEGHQCDRALEILLHPSEPHQPHLMLETGSLSSAEYEAQVRARHDFQRLQQRDSGGERQVWFLQRRFHKDILLNPVLVLNFCPDLSSKPGHLNAATRELLFLLDGSGAGHKDAIVLAVKSLPAQTLVNLAIFGTLVQPLFPESRPCSDDTVQLICESIETLQTVNGPPDMLAVLDWALGQPQHRAYPRQMFLITAASPTAATTHQALEFMRWHRGAARCFSFALAPACRQLLHDLSVLSRGQAYFLRPGERLQPKLVQALRKALEPALSDISVDWFVPDAVEALLTPREIPALYPGDQLLGYCSLFRVDGFRSHALGGQEPGWQSLAGSVFPSPEEVLSATSPGTEPTHTTEPLGTGTVSAELSSPWAVGDSEQSMEALTDPVMDPGPNPSSDTAIWRRIFQSSYIREQYVLTHCSASPEPGPGSTCSSESPGSQGPGSPSGSRPLDPPSQQGCRSLAWVEPAGSRSCPLPVPPPSPFKVGAMSAEVLGRRQRAALAGRSLSSPSGRANPVPGRARHPSLDAIPDGLGPEPGQQLGQGLDDSGNLLSPAPLDWDMLMEPSFLFKPVPSSAESAPPAECLPPQAPRCHVVIRALCGEQPMCWEVGVGLEELWGPGDGSQPESLPMREAAWDQALHRLTAASVVQDNEQLALRGRAETRAEQGRVRRSWLRAIQTSKVSSAPSCFTCPVAVDATTREVLPGALQVWSSDPAELSGMSASQDQLAAAPLSTAVHSKGHQGGCSAGAWDLDLNDNSKSALGEPISPTGDHHGLPHQPPASSRLSLGRHRRLCSSNKGQTHENSNDGSNHDYLPLVRLQEAPGSFRLDEPFCAAVCIPQERLCRASPFAAHRASLSPTSASSPWAFLSPGIGQGDSATASCSQSPSSGSEGPGQVDSGRGSDTEASEGMERQDSSDLRGRTWATAVALAWLEHRCAAAFGEWELTASKADCWLRAQHLPDGLDLTALKAAARGLFLLLRHWDQNLQLHLLCYSPSNV
What are the official names of this protein?
von Willebrand factor A domain-containing protein 5B2.
Protein: DCUP_VARPS
Sequence: MPFAPLQNDTFLRACWRQATDHTPVWLMRQAGRYLPEYVATRARAGSFMGLATNTDYATEVTLQPLERYPLDAAILFSDILTVPDAMGLGLSFEAGEGPRFARPVQGEAAVAALEVPDMAKLRYVFDAVASIRKALDGRVPLIGFSGSPWTLACYMVEGAGSSDYRLVKSMLYSRPDLMHRLLAVNADSVAAYLNAQIDAGAQAVMVFDSWGGVLADGAFQEFSLAYTARVLAGLQRNGADGQPVPRIVFTKGGGLWLEAMRELDCEVLGVDWTVNLSAARRLVGEGTDAKAKALQGNIDPNVLFAPPAQIEAEVAKVLQAFGQPHADAAAKGPTHIFNLGHGISQFTPPDHVAALVQAVHAQSRALRKG
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUAD_PANTR
Sequence: MAASKVKQDMPPPGGYGPIDYKRNLPRRGLSGYSMLAIGIGTLIYGHWSIMKWNRERRRLQIEDFEARIALLPLLQAETDRRTLQMLRENLEEEAIIMKDVPDWKVGESVFHTTRWVPPLIGELYGLRTTEEALHASHGFMWYM
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.  Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death.  This apoptotic activity is inhibited by interaction with viral IRF1.  Prevents the transactivation of STAT3 target genes.  May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, Complex I-B16.6, CI-B16.6, NADH-ubiquinone oxidoreductase B16.6 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA13 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. Nucleus. Note=Localizes mainly in the mitochondrion. May be translocated into the nucleus upon IFN/RA treatment.
Protein: RL18_STRT1
Sequence: MKIVISKPDKNKLRQKRHRRIRGKLSGTADRPRLNIFRSNTGIYAQVIDDVAGVTLASASTLDKEVSKGTKTEQAIVVGKLVAERAVAKGISEVVFDRGGYLYHGRVKALADSARENGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CYSN_SALTY
Sequence: MNTILAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTLQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTERRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYREETFARIREDYLTFAEQLPGDLDIRFVPLSALEGDNVAAQSANMRWYSGPTLLEVLETVDIQRAVDRQPMRFPVQYVNRPNLDFRGYAGTLASGSVKVGERIKVLPSGVESSVARIVTFDGDKEEACAGEAITLVLNDDIDISRGDLLLAANETLAPARHAAIDVVWMAEQPLAPGQSYDVKLAGKKTRARIEAIRYQIDINNLTQRDVESLPLNGIGLVEMTFDEPLALDIYQQNPVTGGLIFIDRLSNVTVGAGMVRELDERGATPPVEYSAFELELNALVRRHFPHWDARDLLGDKHGAA
What is the function of this protein?
With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 1, ATP-sulfurylase large subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: VPR_HV1N5
Sequence: MEQAPEDQGPQREPYNEWTLELLEELKSEAVRHFPRIWLHNLGQHIYETYGDTWAGVEAIIRILQQLLFIHFRIGCRHSRIGVTRQRRARNGASRS
What is the function of this protein?
During virus entry, plays a role in the transport of the viral pre-integration (PIC) complex to the host nucleus.  This function is crucial for viral infection of non-dividing macrophages.  May act directly at the nuclear pore complex, by binding nucleoporins phenylalanine-glycine (FG)-repeat regions.
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 VPR protein family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host extracellular space. Note=Incorporation into virion is dependent on p6 GAG sequences. Lacks a canonical nuclear localization signal, thus import into nucleus may function independently of the human importin pathway. Detected in high quantity in the serum and cerebrospinal fluid of AIDS patient.
Protein: CG24_CANAL
Sequence: MRSYKSSITDENELTKQRLRAKSIANLSSNHTTAGQPSTSSQHREALTDLTSQENKNHPRVKLTQTNTNHHRNSSSSSNKIQIYQQIEQKKTDIHQFKKPRLEKVLLNDDDDETDDEFDDEEDKENRYHDLELNEDDSKHQLISEAFETIDDRGISEGENDTAQEARERLEEETQSHTQDMRSIYGVHVPMQPMWNNAIINELKYVIQKYSRNTLDENDEDTYDTTMVAEYSPEIFNYLHELENKFTPDPNYMDFQDDLKWEMRAVLIDWVVQVHARFNLFSETLYLTVNYIDRFLSKRRVSLSRFQLVGAVALFIAAKYEEINCPTVQEIAYMADNAYSIDEFLKAERFMIDVLEFDLGWPGPMSFLRRISKADDYDYETRTLAKYFLEITIMDSKFVASPPSWLAAGAHYISRILLGRGEWTELHVFYSGYTEKQLQPLADVLLENCRHAEINHKAIFEKYKERRYRKSSLFVQEYFRHIMSQS
What is the function of this protein?
2/mitotic-specific cyclin essential for the control of the cell cycle at the G2/M (mitosis) transition.  G2/M cyclins accumulate steadily during G2 and are abruptly destroyed at mitosis.  Degradation is necessary for the cell to exit from mitosis.  Plays a role in morphogenesis by negatively regulating polarized growth.  Through binding to CDC28 regulates cytokinesis, partly by phosphorylation of the actomyosin ring component IQG1.
What are the official names of this protein?
G2/mitotic-specific cyclin-4.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
Protein: SYH_NEIMF
Sequence: MAQKIQSVKGMNDLLPVEQKDFKLTAAFWQAFEDTVNRWTRAYGYRQIRTPIVEQTGLFVRSIGEETDVVGKEMYTFSDSNDSLSLSLRPEGTASCLRAVVEHNLLYNSPQKLWYMGPMFRRERPQKGRYRQFHQVGIEALGFEGPDIDAEIIAMSADLWEKLGIREYLTLEINSLGNREERAAHRAALVEYLTRYEDKLDEDSKRRLKTNPLRVLDTKNPDLQEICNAAPRLVDYLGEASQNHYARFKAMLDGLGIQYIENPRLVRGLDYYNQTVFEWTTDKLGAQATVCGGGRYDGLIEELGGKPAPSIGFAMGIERLLLLVSEYGSLEVNAAPDVYAMHQGERADLQVMKYAQALRTQGFNVMQHSGYQSLKAQMKKADNSGARFALIVAQDELANGTVTLKDMNGAHGQQTVAAEDLTHTLQQWKNA
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_ACIAD
Sequence: MRHRNSGVKLGRTSSHRKAMFQNLANSLFEHELIKTTVPKAKELRRVAEPLITLAKNDTVANRRLAFARTRSAATVGKLFTVLGPRYKERNGGYLRVLKAGFRAGDAAPMAYVELVDREVNTSAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: GANA_ASPNG
Sequence: MIYPLLLSALPLLSSAALTYRGADISSLLIEEDAGISYKNLNGETQALEDILVNNGVNSIRQRVWVDPSDGSYDLDYNLKLAKRVQAAGMSIYLDLHLSDTWADPSDQTTPTGWSTTDIDTLTWQLYNYTLDVCNTFAENDIDIEIVSIGNEISSGLLWPLGKTSNYDNIAKLLHSGAWGVKDSNQATTPKIMIHLDNGWDWEEQEYFYKTVLATGSLLSTDFDLMGVSYYPFYNSEATLSALQTSLTNMQSNYDKSVVVVETNWPVSCPDPEYSFPSDLSSIPFSAAGQEEFLEKLAEVVEGVTDGLGIYYWEPAWVDNAALGSSCADNLMVDIDTDEVLESVTVFEDL
What is the function of this protein?
Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.
What are the official names of this protein?
Arabinogalactan endo-beta-1,4-galactanase A, Endo-1,4-beta-galactanase A, Galactanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 53 family.
Protein: NREB_STACT
Sequence: MKSISNRDKLQDLLTQYYLNTNEKMVFLNSTGEVIALNEAAEEVFADDNDYSQMTNAVCRRCEGYSNEYDIMSCENCFLEALEIGKGSFQVFIRTKDNKIQPYTASYELIDHEKGIYAFTLHNVSPQIQRQERMYQRKMMQKTISAQENERKRISRELHDGIVQELINVDVELRLLKYQQDKDELIDNSKRIEGIMSRLIDDVRNLSVELRPSSLDDLGLDAAFRSYFKQFEKNYGIHVNYHTNFSAQRFDNEIETVVYRVVQEALFNALKYAQVDIVEVSLQLNENNIIAEVSDRGVGFKRGDDPKGTGLGLFGMNERAELVNGTVNIDSQINRGTIVTLEVPITD
What is the function of this protein?
Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen.  NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC.  NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.
What are the official names of this protein?
Oxygen sensor histidine kinase NreB, Nitrogen regulation protein B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL2_METFK
Sequence: MALIKVKPTSPGRRSVVKVVTPELHKGKPYAPLLEKQSKKAGRNNNGHITTRHQGGGHKQHYRIVDFRRNKDGIPAKVERLEYDPNRSAHLALLVYADGERRYIIAPRGVSVGAQLVSGSDAPIRAGNALPLRNIPVGSTIHCIELQPGKGAQVARSAGTSVQLLAREGSYAQLRLRSGEVRRVHVDCKATIGEVGNEEHSLRSIGKAGAVRWRGVRPTVRGVVMNPVDHPHGGGEGKTAAGMNPVSPWGLPTKGYRTRSNKRTDNMRVSRRPANKR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: ATU_DROME
Sequence: MGSQNSDDDSGSSGSSRSGSRSVTPQGGSAPGSQRSRRSGSGSDRSRSGSRSSRSRSGSGSPRSARSGSAESRHSQLSGSARSKRSRSAHSRRSGSARSRKSGTPESPQSHRSGSLQSRKSGSPQSRRSGSPQSRKSGSTHSRRSGSAHSRRSGSARSRKSGSAQSDRSESRSRSHSGSLKGNEESRSNSPNLQIDVERANSKSGSRSRSRSRSGSRTSRSRSKTGTPSPNRSRSGSASGSGSDVGVPKKKARKASGSDQEKKKSGSDSDIEESPTKAKKSRLIDTDSDSNQDVGKKAPAAADIFGDADDISDDEDEAGPAARKSPVRSKSRSQSKSHSHSRSMSHSRSRSRSRSRDKVESQVESAPKEDEPEPLPETRIDVEIPRISADLGKEQHFIKLPNFLSVVTHPFDPETYEDEIDEEETMDEEGRQRIKLKVSNTIRWREYMNNKGDMVRESNARFVRWSDGSMSLHLGNEIFDAYRQPLLGDHNHLFVRQGTGLQGQSVFRTKLTFRPHSTESFTHKKMTMSLADRSSKTSGIKILTQVGKDPTTDRPTQLREEEAKLRQAMRNQHKSLPKKKKPGAGEPLIGGGTSSYQHDEGSDDENAISLSAIKNRYKKGSGAGQAEVKASTIYSSDEDEGSDFEARRSKKVDKAKASKALRDSDSESDAGSAKSGHSNKSGGEGGSASGSENEGSQKSGGGSSKSASGSGSGSGSGSGSGSDND
What are the official names of this protein?
Another transcription unit protein.
Protein: HIS6_PSEU2
Sequence: MALAKRIIPCLDVDNGRVVKGVKFENIRDAGDPVEIARRYDEQGADEITFLDITASVDGRDTTLHTVERMASQVFIPLTVGGGVRTVQDIRNLLNAGADKVSINTAAVFNPEFVGEAAARFGSQCIVVAIDAKKVSGPGETPRWEIFTHGGRKPTGLDAVLWAKKMEDLGAGEILLTSMDQDGMKNGFDLGVTRAISDALGIPVIASGGVGNLEHLAAGVIEGHASAVLAASIFHFGEYTVPEAKAYMASRGIVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_BORPA
Sequence: MLQYPQIDPVALRIGPLAIHWYGLMYLIGFALVYALGRRRITSGHTTSMTVRDLEDLIFYSVLGVVLGGRLGYVLFYKPAYYLANPLEIFYLWEGGMSFHGGLIGVIVVMLLFAHKKRLGFFTVSDFIAPLIPLGLAAGRLGNFINGELWGRPTDVPWAMVFPQSGDGLPRHPSQLYELGLEGIVLFALLWWYSSKPRAAGQVSAMFLMGYGAFRFLVEFTREPDNFLGLLAAGLSMGQWLSIPMVLAGAGLYLFTARPPSR
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y6639_PARXL
Sequence: MNSTPDTSSRPSIRALTLLEGRVLGVLVEKQHTVPDSYPLSLNALTLGCNQKTGRAPVMNATEAEVLTAVDGLKRLSLVMEGSSSRVPRFEHNMNRVLGLPSQSAALLTTLLLRGPQTAAELRLNSARLHGFADISSVEAFLDELAANDPPRVVKLARTPGERENRWTHLLCGEVSASELAQPGAEDDAVPLSAFEAVKAEQKRLADEVSRLQTVVRRMAAELGIDAGDLTAGEGA
What are the official names of this protein?
UPF0502 protein Bxeno_B1639.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: GLCAP_SOYBN
Sequence: MMRARFPLLLLGVVFLASVSVSFGIAYWEKQNPSHNKCLRSCNSEKDSYRNQACHARCNLLKVEEEEECEEGQIPRPRPQHPERERQQHGEKEEDEGEQPRPFPFPRPRQPHQEEEHEQKEEHEWHRKEEKHGGKGSEEEQDEREHPRPHQPHQKEEEKHEWQHKQEKHQGKESEEEEEDQDEDEEQDKESQESEGSESQREPRRHKNKNPFHFNSKRFQTLFKNQYGHVRVLQRFNKRSQQLQNLRDYRILEFNSKPNTLLLPHHADADYLIVILNGTAILTLVNNDDRDSYNLQSGDALRVPAGTTYYVVNPDNDENLRMITLAIPVNKPGRFESFFLSSTQAQQSYLQGFSKNILEASYDTKFEEINKVLFGREEGQQQGEERLQESVIVEISKKQIRELSKHAKSSSRKTISSEDKPFNLRSRDPIYSNKLGKLFEITPEKNPQLRDLDVFLSVVDMNEGALFLPHFNSKAIVVLVINEGEANIELVGIKEQQQRQQQEEQPLEVRKYRAELSEQDIFVIPAGYPVVVNATSDLNFFAFGINAENNQRNFLAGSKDNVISQIPSQVQELAFPGSAKDIENLIKSQSESYFVDAQPQQKEEGNKGRKGPLSSILRAFY
What is the function of this protein?
Seed storage protein.  Accumulates during seed development and is hydrolyzed after germination to provide a carbon and nitrogen source for the developing seedling.
What are the official names of this protein?
Beta-conglycinin alpha' subunit, CG-alpha'-1, Beta-conglycinin alpha prime subunit.
What is the protein family that this protein belongs to?
Belongs to the 7S seed storage protein family.
What are the subcellular locations of this protein?
Vacuole, aleurone grain. Endoplasmic reticulum. Protein storage vacuole. Note=Localizes in protein storage vacuoles in cotyledons of developing and mature beans (PubMed:17181539, PubMed:15447650, PubMed:12787246, PubMed:16900322). Synthesized and assembled into trimers in the endoplasmic reticulum, and transported to the protein storage vacuoles by the dense vesicles (PubMed:15447650).
Protein: FTSK_LISMO
Sequence: MATQKKKTSGRKKSSTRSKKKQSASFRLEITGVILIAIGVIGLLQLGFVGRGFFALAEMFVGLLSYVLLAGSVILGGYMVIRRKMPHLFSKRLVGIYLIVLGFLTYIHMYFIIHNLGANASVVSSTWKLVLENLFRPNQVGFVGGGMIGAAITSITYFLLDRLGTNLIAVLLIIYGFSLVSGISIRQFFSKIAEFVRYLFTKGKVATEKGKEVKAKRDKKKAEKIVDVEPDEVIDVIEPLQEEKTPPIISNFSSKVEQEKAPVEEKISQKEQDLEMFQQESFENEIYQLPPVDILAPAKVTDQSKEYDQIKVNAKKLEDTFESFGVKAKITQVHLGPAVTKYEVQPSVGVKVSKIVSLSDDIALALAAKDIRIEAPIPGKSAIGIEVANQNVAMVSLREVLENNPKNNPDEKLQIALGRDISGEAMMANLDKMPHLLVAGATGSGKSVCINGIITSILLRAKPHEVKMMMIDPKMVELNVYNGIPHLLAPVVTNPKKAAQALQKVVAEMERRYDLFSHTGTRNMQGYNDYVKKHNELNEEKQPELPFIVVIVDELADLMMVASNDVEDAITRLAQMARAAGIHLIIATQRPSVDVITGVIKANIPSRIAFAVSSSIDSRTILDMGGAEKLLGRGDMLLLPVGSSKPTRIQGAFLSDAEVEDVVNYVISQQKAQYSEEMIPDDIPEVEGEVTDELYHEAVELVVEMQTASVSMLQRKFRIGYNRAARLIDEMEQRGVVGPHEGSKPRRVNVEVSPEHE
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: CENPT_RAT
Sequence: MADLSSPDGDPTIRTLLRHVLDTADSHTPRRRQSTQTNPQRRRSQTPYSKRQGSQRKTSTRKHSHGTGSVGRLARVQGHGHLEEQTPRTLLQNILLTAPESSTVMPNPVVKPAQVPEVARPSRRGSSRGSLELQLPELDPPSTLAPGLKAPGKRKQKLRLSVFQQEVNQQLPLPQEQRGAADGSSLASSFNLSFVPSVQPQTVDRPGLARRRPVRRPVNIGAFLQNLENKSLTSALPGDSHRTPVAALPTDVVFEDTQPFSQPLAGCSLSVHHSLPNPSQTEVEDAERVVGPRTPSTGTRPQSQMSRAGFGASPLPFSEPQPQSPELREAVGSKEAEEPKDLEGSSGDEETSGMPASRELSSSAQDLLLAEEPHQLFEPPPSPGVAAVSSESVPAKLPSRTRTAQPRHHQDPYKAGLSHYVKLFSFHTKMPVEKAALEMVEKCLDEYFQRLCNDLEVFAAHAGRKTVKPKDLELLMRRQGLVTDQVSLHVLVERYLPLEYRQQLIPCAFRGNSVFPAQ
What is the function of this protein?
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres.  Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA.  Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly.  CENPT has a fundamental role in kinetochore assembly and function.  It is one of the inner kinetochore proteins, with most further proteins binding downstream.  Required for normal chromosome organization and normal progress through mitosis.
What are the official names of this protein?
Centromere protein T, CENP-T.
What is the protein family that this protein belongs to?
Belongs to the CENP-T/CNN1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Constitutively localizes to centromeres throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may connect it to the outer kinetochore via its N-terminus.
Protein: RS14_PARMW
Sequence: MAKKSMIARDVKRKKMAERYAAKRAALMAAFNAADDPMDRLEIHRKIQALPRNSAPSRIRNRCWATGKPRGYYRDFGLCRNQLRERAHKGELPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: HSLV_LEPCP
Sequence: MESFHGTTILSVRRGEQVAMGGDGQVTLGHIVVKASARKVRRLYREQVLAGFAGATADAFTLFERFESKLEKHQGHLVRAAVELTRDWRTDRVLRRLEAMLAVADRSASLIITGNGDVLEPEYGIVAIGSGGAYAQAAARAMLQHTEQSPADIVKRSLEIAGDLCIYTNQSHTIETLE
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_STAHJ
Sequence: MTATWEKKEGNEGLLKVTVPAEKVDKALDQAFKKVVKQINVPGFRKGKVPRPIFEQRFGVEALYQDAVDILLPEAYGEAIDETGINPVAQPEINVTQIEKGKDFEFEATVTVEPEVQLGDYKGLEIEKQDSELTDEDLQEAIDHSLGHLADMVVKEDGAVENGDTVNIDFDGYVDGEQFEGGQADGYDLEIGSGSFIPGFEDQLVGVKTGEEKDVVVTFPEEYHAEELAGKKATFKTKVNEIKYKEVPELDDEIANELDSDANSVDEYKENLRKRLSEQKAEEAENVEKEEAINKATDNATIDIPQAMIDTELDRMVQEFGQRIQQQGLDLQTYFQISGQDESQLREQMKDDAEQRIKTNLTLSAIADKENIEANDEDIDKELEKMSKQFNISVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKYVESTKEDK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: NADE_STRZT
Sequence: MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFVLGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQPDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGTDHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDKPGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: LOLD_NITEU
Sequence: MSKIIIACRDLYKSYFQGNLEVPVLHGIDLQVNEGEMVAIVGASGSGKSTLLHVLGGLDKPTRGEVTLLDRELSTISEAERGSLRNHALGFVYQFHHLLPEFSAQENVAMPLFIRRMNKKAAMEQAAAMLQRVGLGHRLTHTPGELSGGERQRAAVARALVTRPACVLADEPTGNLDRHTAEAVFDLMLELNHEANAGLVIVTHDTQLASRADRVLHLVDGMLQ
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DNJC4_MOUSE
Sequence: MPSLLLQLPLRLCRLWPHSLSIRLLTAATGQRSVPTNYYELLGVHPGASAEEIKRAFFTKSKELHPDRDPGNPALHSRFVELNEAYRVLSREESRRNYDHQLHSASPPKSSGSTAEPKYTQQTHSSWEPPNAQYWAQFHSVRPQGPESRKQQRKHNQRVLGYCLLLMVAGMGLHYVAFRKLEQVHRSFMDEKDRIITAIYNDTRARARANRARIQQERQQRQQPRAEPSLPPESSRIMPQDTSP
What are the official names of this protein?
DnaJ homolog subfamily C member 4, Multiple endocrine neoplasia type 1 candidate protein number 18 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.