PharMolix/UniProtQA huggingface dataset:
Protein: RS18_IDILO
Sequence: MARFFRRRKFCRFKADGVKEIDYKDIATLKNYITETGKIVPSRITGTSAKYQRQLARAIKRARYLSLLPYTDSHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FIP1_ASHGO
Sequence: MQLRAAQHLIAEELQMASSDDEDEKFLYGSEDEADGPRGQQKRKLIPQGTAQIQEPDTKRARGADDGDVDMLDDDDEEEDDDEDEDDEDSDSDVEIIIGTGADSSKLDSKALTTPSTAATATSAAESAIAPVSEQSAPVAAVQSGDSGAAMDKAVGALDINAVGEYEGTPITDIDPEVLKEKPWRQPGANLSDYFNYGFTEETWMEYLHKQEKLRKEYNPRKILMGLLALQQQGKLGDGGAGDGVMLSAGGMAHNDIKSPNKNNGSLPQPPAFPMGMPPMFGGFPPFPFPGMIPPNLGAASGNNGSGNHQNMGTSSGNGNNGK
What is the function of this protein?
Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase.
What are the official names of this protein?
Pre-mRNA polyadenylation factor FIP1.
What is the protein family that this protein belongs to?
Belongs to the FIP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYR_CHLAA
Sequence: MRYALERFISDIQAAIVATGKVPADLIEITTPKPNIPADRTFVTFKAAKALGVDPVRLAADLATAIVPPPDSLIGEVTATGAFLNFTLHPQRLAAAVMAEIETYGDAYGSVADGANRTVVIDYSSPNIAKRMHVGHIRSTIIGQALVHIFRALGYRVIGDNHLGDWGTQFGIILAAMQRYGRPQNEGEAAMAELEALYARYNAEMKDNPPLEDEARRWSLALEQGDPTARELWQWCVDLTMRAAQRNYDRLGVRFDYAYGESFYEAMLPGVIEEALQSGAAFRDVDGAVVAELDKLPRFIVQRSDGGTVYITRDIATIKFRLQEFNPSHIIYVVDARQELHFRQLFAIVRAMGYALDVELIHVPFGVITTPDGQPLSTKKGNMVYLESLLDDAVARARALVDAKSPTLSPEERAQIAEAVGIGAVIYNDLYQDPRRNITLDWDRMLSIEGNSAAYLQYSHARCRSILRRAAEEGMLSTEVDPGLLTHPSEQRLVRHLARLPEAVREAGARYAPFVIADWCYTTAREFGIFFEQCPVLRAETPALRAARLQLVSATANALRNGLALLGIQAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_PROMM
Sequence: MPKYHLKAPYSPKGDQPTAIARLVEGVNQGQRYQTLLGATGTGKTFTIANLIAQTGRPALVLAHNKTLAAQLCNEFREFFPDNSVEYFISYYDYYQPEAYVPVSDTYIAKTSSINEEIDMLRHSATRSLFERNDVIVVASISCIYGLGIPSEYLKAAVKFKVGETLNIRSALRELVENQYSRNDIDITRGRFRVRGDVLEIGPAYEDRLVRIELFGDEVEAIRYLDPTTGEILQSLEAINIYPAKHFVTPKERLNVAVQAIRDELRGRLQFLNEQGKLLEAQRLEQRTTYDLEMLREVGYCNGVENYARHLAGRSAGTPPECLIDYFPEDWLLVVDESHVTCSQLKAMYNGDQARKKVLIEHGFRLPSAADNRPLKSEEFWSKARQTVFVSATPGDWELKQSDGHLAEQVIRPTGVLDPLVEVRPTQGQVDDLLAEIRIRAEKQERVLITTLTKRMAEDLTDYLAENDVRVRYLHSEIHSIERIEIIQDLRLGEYDVLVGVNLLREGLDLPEVSLVVILDADKEGFLRAERSLIQTIGRAARHVDGMALLYADNLTDSMSRAISETERRREIQKAYNELNGIVPRPAGKRASNSILSFLELSRRLQTDGKDADLVQITGRAVDALDSDQDAGLALDALPELIDQLETKMKEAAKNLNFEEAASLRDRIKKFRQKLIRNT
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMG_MICAN
Sequence: MTFSSAADFQDEFDVIVVGAGHSGCEAALACARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMADRTYLQKRVLNASRGPAVWALRAQTDKREYAAVMKGIVETQANLVIREAMATDLILGANEQVLGVETYFGTCFAAKAVILTTGTFLGGKIWIGGKSMAAGRAGEFAAVGLTETLNRLGFETGRLKTGTPARVDKRSVDYSRMEPQPPDDEVRWFSFDPEVWIEREQMNCHLTRTTAATHQLIRDNLHLSPIYGGFIDSKGPRYCPSIEDKIVRFADKESHQIFIEPEGRDIPELYIQGFSTGLPENVQLAMLRTLPGLENCVMLRAAYAVEYDYLPATQCYPTLMTKKIEGLFCAGQINGTTGYEEAAAQGLVAGINAARFALGKELIVFPREESYLGTLVDDLCTKDLREPYRMLTSRSEYRLVLRSDNADQRLTPLGREIGLIDNRRWQLFQSKQANIIAEKERLHETRIKERDQVAIAIVKDTEQKIKGSLSLADLLRRPSLHYLDLDRYGLGNPDINLAEREGVEIEIKYSGYLKRQQNQIDQISRHSNRHLSPDIDYMKIETLSMESREKLTKIKPATIGQASRIGGVNPADINALLVYLEMRQMSAVKS
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_CAMJ8
Sequence: MEFKLKHKDGMARVCEITTAHSTFLTPVFMPVGTVGAVKSLDANDMKNELDAKIILANTYHMYLRPTSKVVKDFGGLHGFTKFDRSFLTDSGGFQAFSLSKNSKHFNEGIEFKSHIDGSRHLFTPKSVLDTQYDFNSDIMMILDDLVALPATKERVKISVDRTILWAKEAITYHKSMQNKGIGIGQNIFGIIQGGTDYKERKRCALSLNEMPFDGLAIGGLSVGEENALMYETVQNLNPYLDENRPRYLMGVGTPEDLVENVERGVDMFDCVMPTRNARNGTFFTSFGKFNIKKAEFINDHEAIDPACSCYTCCNFSRGYLNHLFKAKELTFFRLASLHNLHYYLELARKMREAILNNSFTQFKRNFYHLRGK
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: DNLJ_AGRRK
Sequence: MSSEQKPVEDLTEEEAAAALAYLAAEIARNDALYHGNDAPEISDAEYDALKRRNDAIEARFPALVRADSPSRRVGAAPSETFMPVVHARPMLSLDNTFSQEDVQDFVAGVYRFLGRLPDQSIAFTAEPKIDGLSMSIRYENGRMVSAATRGDGTTGENVTANIRTIKEIPQTLPAGAPAVVEIRGEVYMAKSDFLALNAQMEAEGKQSYVNPRNTAAGSLRQLDAKVTASRKLKFFAYAWGEMSDMPADTQFGMVQAFGEWGFPVNPLMKRLNSVADILAHYDEIGLQRPDLDYDIDGVVYKVDSLELQARLGFRSRSPRWATAHKFPAEQALTRLLDIDIQVGRTGALTPVARLEPITVGGVVVTNATLHNADYIKGIGNKGEPIRDGRDIRIGDMVIVQRAGDVIPQIVDVVLEKREASSVAYEFPKTCPVCGSHAVRDINEKTGKVDAVTRCTGGFICRAQATEHLKHFVSRNAYDIEGLGSKQIDFFFESDDPALQVRTAPDIFTLERRQQSSLSKLENIDGFGKVSVSKLYAAINERRDIALHRFIFALGIRHVGETTAKLLARSYGTYEAFEAGMKEAAPLAGDAWNDLNNIEGVGEVVARAVVEFYKEPRNVEVISKLLDEVRPQEAEQPTTSGSPVVGKTVVFTGSLEKFTRDEAKAKAESLGAKVSGSVSKKTDIVVAGPGAGSKLDKAREFNVQVMTEDEWLELIGG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PLSB_PSEA6
Sequence: MAWLHKLLLTMISVPLKWLVKVNSIPTDIATELGIDNTKPIIYLLRTHSVTDQFALKMSTNSLGLPKPSEPVQIGGKELPACLFLQQPRSLLTRKVKITKIADDVTRLFQLHREHPELDLQIVPVSIFWGRAPGRKLSGWSDIIANQVSPNWLRKFFIVLFLGRDNFVCYSKAVSSRTMADLKGSDEEIGHKLIRLAGTHFHRRRQNLIGPMLLERQELYNAVLGADSVRQAVSDEARSKKQSNHQIQAKAKKYVDEIAADYREGLVRIGDRLLTKIWNKVYNGIEVKHADKVRALAQNGHEIIYVPCHRSHMDYLLLTYVIYHEGLVTPHIAAGINLNFWPIGGILRKCGAFFLRRSFAGNKLYTAVFREYLELLFNKGYSVKYYPEGGRSRTGRLLPPKTGMLAMTLQGLIKGINRPVSIVPVYIGYEHVMEVSSYLKELKGTDKKKESFFQVFSAVRKLKNYGNGFLNFGDPINLSNFLDSEVPDWREAQNLEPDKKPRWLTPAVNTLANDVMGRINQAAAVSGMSLCAMCLLSAKKHAMAQDELERAIDDYLDLLKAAPYSDLSSIPELDGKALVENTLKLNKLEVSQDSFGTIISLKRKNAVALTYYRNNILHLFALPGLVSAIVFAHKGLARPQVISLVGQLYPLLQRELFIYMSHEEAMNYTDRLLSTMIDIGLLRAEDDTLCPPAATSKAFYSFWLLNRSIQETLQRYAAVLTILKKEQTIGRGRLEKQSREFAERLAALHGINSPEFFDKNVLSTFIHALKDNELINASSEGQLQHSDTSEALLASVEELISPEITQRLQQI
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: AGAL_HUMAN
Sequence: MQLRNPELHLGCALALRFLALVSWDIPGARALDNGLARTPTMGWLHWERFMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFGYYDIDAQTFADWGVDLLKFDGCYCDSLENLADGYKHMSLALNRTGRSIVYSCEWPLYMWPFQKPNYTEIRQYCNHWRNFADIDDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIMAAPLFMSNDLRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVASLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLLQLENTMQMSLKDLL
What is the function of this protein?
Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome.
What are the official names of this protein?
Alpha-galactosidase A, Alpha-D-galactosidase A, Alpha-D-galactoside galactohydrolase, Galactosylgalactosylglucosylceramidase GLA, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: SCAP_XENLA
Sequence: MPLIDKLRERISRAFYSHGLLCASYPIPIIILTALCILASCYPLLKLPLPGTGPVEYVTSVKDYSPPPLEPNPEDHSDQPDWYVGLPVAFIQQVLVKAVVSPWDKDFLAVDVFRSPLSRVFPLVEEIRNHVLRDKSQEKSLEDVCLQVTDLLPGLKKFRDKLPEHGCLLLSPANFWQNSQEQFSSDPDLIRTIHQHEPKTLQTSATLKDLLFGVPGKQSGVSLYNRKRIVSYTVTIALRRYNATFLDSLRSRLKRQHPSTNSSAASQHIVHVHFKEEIGIAELIPLVTTYIILFAYIYFSTRKIDLVKSKWGLALAAVVTVLSSLLMSVGLCTLFGLTPTLNGGEIFPYLVVVIGLENVLVLTKSVVSTPVDLEVKLRIAQGLRNESWFIMKNMATELGIILIGYFTLVPAIQEFCLFAVVGLVSDFFLQMFFFTTVLSIDIRRMELADLNKRIPAEACIPPPKPGAKRYDRQPTLRPATPHTITLQSLRNLRLPKRLRLVYFFARTRLAQRIIMAGTVVWIGILVYTDPAGLRNYLTVHVTEQSPLGGAVMPPIPVPVLSASNPHGPLSAVFPTGSSQLLENQSQRDSKEVIDSLSSRIWEESHPEDKSKERAAKIEDKAHTQVTWGAEDEETWRKLSFRHWPTLFSYYNITLAKKYISILPMIPVTLYLTPQEVSDARHPQEAQHSHPYLQREGKPDEAWARVEAKGAEKPTENQTPADVTLYKVAALGLASGIFLVLFFFLLYRLLCPKNYGQNGVSHGRRKKGDLPCDDYGYSPPETEIVPLVLRGHHMDIECLASDKMLLVSCCLAGQIRVWDAQSGDCLTIIPKPSLRRESSGVFEYQDNWEPTPECKYNPEESLENGYQLKRRTLHPPLFSDQPDLTSLIDTNFSEQPANEESGARQRLSCIKQESPPIGYDFSSLVQKVYEEHEVSSFGSFPLVLSPAPYGQCQLSSGRRSQTPAGCVDGSCARRKSSTEETTGYCNGSSSPAPSWTDSFESSVWSLGLQGNLIVVGRSNGNLEVWDAIEGSLRCSNCDGQSGITSLVFLNHRVVVARLNGSMDFYCLDSQKSSNQLQFRGAPNRSNVPSSPLYSTDDVIGCQRTHTVACAHRKPITALKAAAGRLVTGSQDHTVRIYRLEDACCLFTLQGHSGGITAIYIDETMVLASGGQDGAICLWDVLTGSRVSHMFGHRGDVTSLLCTASCVISSGLDDVISIWDRSTAIKLYSIQQDLGCGSSLGLISDNLLVTGGLGCVSFWDVGYGDLLQTVYLGKCEDSQPARHILVLDNSAIVCDFGSELSLVYVPSVLEKLD
What is the function of this protein?
Escort protein required for cholesterol as well as lipid homeostasis.  Regulates export of the SCAP-SREBP complex from the endoplasmic reticulum to the Golgi upon low cholesterol, thereby regulating the processing of sterol regulatory element-binding proteins (SREBPs) srebf1/srebp1 and srebf2/srebp2.  At high sterol concentrations, formation of a ternary complex with insig (insig1 or insig2) leads to mask the ER export signal in SCAP, promoting retention of the complex in the endoplasmic reticulum.  Low sterol concentrations trigger release of insig, a conformational change in the SSD domain of scap, unmasking of the ER export signal, promoting recruitment into COPII-coated vesicles and transport of the SCAP-SREBP to the Golgi: in the Golgi, SREBPs are then processed, releasing the transcription factor fragment of SREBPs from the membrane, its import into the nucleus.  Binds cholesterol via its SSD domain.
What are the official names of this protein?
Sterol regulatory element-binding protein cleavage-activating protein, SCAP, SREBP cleavage-activating protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat SCAP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, COPII- coated vesicle membrane; Multi-pass membrane protein. Note=Moves from the endoplasmic reticulum to the Golgi in the absence of sterols.
Protein: Y425_CHLTR
Sequence: MRRSVCYVTPSVARAGQISTWRFEYSSANFLPEGTLLKFDLGIDGRPIDWEIPSTDLSQPCNTIYLETPSEDIVAAKAVYAPGGYIPTFEFTLPCDVEAGDTFSIILGSSPNFPQEDSSGNGAQLFTQRRKPFSLYVDPSGKGSFEDPDIFTMDIRGNVLKNIRIFAPSYVIKNKRFDITVRFEDEFGNLTNFSPEETHIELSYEHLRENLNWQLFIPETGFVILPNLYFNEPGIYRIQLRNQATKEVFTSAPIKCFAETSSHLLWGLLHGESERVDSEGNIESCLRYFRDDCALNFFATSSFEIQDGLTPETIKTINQTVADFNEEDRFIALSGAQYLSEEPGEGIREVLLMKEPKSPGKHKECKLFPLSKLYKQSTSHELISIPSFTASKKFGYNFNNFHPEFERVVEIYNAWGCSERTEAEGNPFPIKGSIDSENPEGTVLSALKRNLRFGFVAGGLDDRNLYNHFFDSDQQQYSPGLTAVICNKYSRDSLLEALYQRQCYATTGQRIIVNFQITSAPMGSELSTAIKPGLVINRHISGYVAGTAKIASIEIIRNEDILHTFHPDGNNFEYEYDDLSPFAQVTLKDPQNGAPFAFYYLRVTQENGAMAWSSPIWIDLN
What are the official names of this protein?
Uncharacterized protein CT_425.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0512/CT_425/TC_0708 family.
Protein: TDXH_IGNH4
Sequence: MPGQIPLIGEKLPEMVVHTDHGPKKLPDDYKGKWLVIFSHPADFTPVCTTEFVAFAKRYEDFKKLNTELLGLSVDNSFSHIKWKEWIKEKLNVEIPFPIIADPLGQVATKLGMLHPEGGVVTVRAVFIVDPEGKVRAILYYPLNVGRNIDEILRLLKALQVTDKLGRATPANWPCNEIVKDHVIVPPASTEQEAKERLQKYECFDWWFCHEKAPAEDVEEAKKFLERPAKELCK
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Peroxiredoxin, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. Prx6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD2_DEIGD
Sequence: MTARLLRGGPAADALLAEATARAARLPAPPQLVMLRLGEDPASVSYVRGKDRKAREVGLKSTVYALPETTSQAELLDLIARLNADDTVNGILVQLPLPLHIQEQAVLHAIDPRKDVDGFHPLNVGELWAGRPALRPCTPAGILYLLDHYGIPVAGQRAVVVGRSSIVGRPLAGLLLHRDATVTVAHSRTPDLGAVTREADLLCVAVGRPHLITPDMVRPGATVVDVGINRVLGEGGGKAQLTGDVAPEVAQVAGAITPVPGGVGPMTIAQLLANTVLAAELQAKGRAAR
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD 2.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PG195_VACCC
Sequence: MRSLIIVLLFPSIIYSMSIRRCEKTEEETWGLKIGLCIIAKDFYPERTDCSVHLPTASEGLITEGNGFRDIRNTDKL
What are the official names of this protein?
Protein OPG195.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae B9 protein family.
Protein: TARI1_STAA8
Sequence: MKYAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILINDFEKIIIATPQQWMTHTKDTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGINDDDVIVTHDAVRPFLTHRIIKENIQAALEYGAVDTVIDAIDTIVTSKDNQTIDAIPVRNEMYQGQTPQSFNINLLKESYAQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKVTTPYDLKVANAIIRGGIADD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: PAN2_CHATD
Sequence: MDADWDEVTRIAYPAPGTNDFPRPATAVAFDPIAELLWAGFDRGRVCSFYGRDLTRYTAFKIQPASEGPVRQFLFHDKGVIVLGTRSVHMAMRRGPALWNIRHENMKDLRCMSFTSKGTQEIIVAGWQDTMLVIDVLKGDIIKQIPAQHHYSIMKKSRYICAATKTGSVDLIDPLSFKIVRSWQAHASYINDMDAQNDFIVTCGGSLKQQAAQTYMLDPYVNVFDLKNMASMKPMPFPPLAAHVRLHPRMLTTAIVTSQHGQMHVVDIMNPNSSTVRYANISSYVKLFEIAPSGEALVIGDADCNIHLWGSPTKIHFTDMAIPIELPEPEEPAPVLDWSIETPLSSIGLPYYREPLFSAWPADIISDVGAPPLQLEPSFVATLKQAEWGLYGKNTRNVRRNQVEDTRNTNKQSNALQAPKFLSERARESALSSGGDSSSDPQVDQEPEDPNEIESLKPEAPPLYRNLEIKYSKFGVDDFDFGYYNKTRYAGLENHIPNSYANSLLQLMHYTPLLRNMALQHAATACVSDLCLLCELGFVFDMLQKAEGATCQATNMFKALSGTPQAAPLGLLEEETHVPSLATMAQNLSRFLLEKIHNEYRTIPPISTALEQSLFNFPHPPTPDELVAKVLATSAVATIKCMNCRSETTRPGTTHVIDLLYPPPKTAGRGGRASKVTFSQVLKMGVERETTSKGWCSRCQRYQNLQMRKTIHSVPAVLVVNAGVSNQEHRKLWSTPGWLPEEIGIIVDQGQFFCFEGEDLKLHLQRGIHNITVYSLIGMVINIESHSPQKSHLVGIINVAHAEATPPGENKWHLFNDFSVRPVSAAEALTFNAAWKMPAVLLFQIKSANNKSNLDWKTNLDTSILYKDTNPNTEKKTYRTLDQERERPGPDTIVALDTEFVSLKQPEIQMNSDGERETIRPMSHALARVSVVRGQGENEGSAFIDDYIAIREPVVDYLTLYSGITASDLDPRTSKHNLVSLKTAYKKLWVLLNLGCKFLGHGLKQDFRVINIQVPRAQVIDTIEVFYLKSRLRKLSLAFLAWYLLKEDIQLETHDSIEDARTALKLYRKYLEFDDAGILEAMLEDIYKAGRATNFKPPRREDREKELQRQSTPPNSTAPNDCGAKPDGNGNENGGEPATPARKTGGITAPTFGAVNVFGTPSKASSPLPK
What is the function of this protein?
Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1.  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex catalytic subunit PAN2, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 2, PAN deadenylation complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family. PAN2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_RICAE
Sequence: MHNIFKGLITALITPFKDNKLDLYALERIVKHQIKHEVDAVLIAGSTGESSSLSFEEYKLLLQTSVEIVNKCIPIISGCSSNNTTYARALAAESTKIGVDGFMASPPSYVKPTQHGIYKHFEALHEVCNLPIMLYSAPTRSGVDFSDETILRLSKLPRILALKDCGVDLERPLRIRATVKKDFNILTGNDEVVLAFNAQGGVGWTSVASNIVPNICKELLEKWNKNDTKGALEIHQKLLPLYTALFVESNPIPIKYAAHYLGLCENEIRPPLTEASDSAKKQIENIITSLSIKI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTAD_BACAN
Sequence: MKTTYVNATIVTMNEQNEVIENGYIIVENDKIIDVNSGEFASDFEVDEVIDMKGKWVLPGLVNTHTHVVMSLLRGIGDDMLLQPWLETRIWPLESQFTPELAVASTELGLLEMVKSGTTSFSDMFNPIGVDQDAIMETVSRSGMRAAVSRTLFSFGTQEDEKKAIEEAEKYVKRYYNESGMLTTMVAPHSPYTCSTELLEECARIAVENQTMVHIHLSETEREVRDIEAQYGKRPVEYVASCGLFKRPTVIAHGVVLNDNERAFLAEHDVRVAHNPNSNLKLGSGIANVKAMLEAGMKVGIATDSVASNNNLDMFEEMRIATLLQKGIHQDATALPVETALTLATKGAAEVIGMKQTGSLEVGKCADFITIDPSNKPHLQPADEVLSHLVYAASGKDISDVIINGKRVVWNGECKTLDEERIIFEASRYKRGLQR
What is the function of this protein?
Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively.  Is also able to deaminate adenosine.
What are the official names of this protein?
5-methylthioadenosine/S-adenosylhomocysteine deaminase, MTA/SAH deaminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
Protein: 374R_IIV6
Sequence: MDIEFGNEYRTYGVGLGGYIEGMERGGVANRLNQMLMNPEEKFFSTLNLAFEKINDYRPLDANTRDLMADFATKMPHLSFKNATTFVLGCLASIKHKNNVLNKNEIKKIFSLLHHFKDTENISPSDVIRYAKFAMINNFYIEDLDINEEDDEEYGDEEYGDEEYE
What are the official names of this protein?
Uncharacterized protein 374R.
Protein: SYGB_SALSV
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGNVEWFAAPRRLALKVANLAESQPDREVEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLKTDKGEWLLYRAHVKGESTEALVPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPQILLERGKVIADYEARKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYDNAGKLLPNFIFVANIESKDPTQIISGNEKVVRPRLADAEFFFNTDRKKRLEDHLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAGQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAARLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEEASALAAANKRVSNILAKATEPLNDIVHASVLKEAAEIELARHLVVLRDKLQPYFADGRYQEALIELAALRAPVDEFFENVMVNAEEKDIRINRLTLLSKLRELFLQVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRB_ECO8A
Sequence: MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB1_PSYIN
Sequence: MLKDPKQVHAPNFGVVVSVRGSVVDIRFDESLPPIHRLLRVVGIFIVIEVLAQRDARVVRGIALTPTQGLARGMRVEDSGGPLTAPVGKAIISRMFDVFGNTIDNGPLLNNVQWRSVHRAPPTLSQRSTQSEIFVTGIKVIDVLVPLERGGKAGLFGGAGVGKTVLLTEMIHNMVSHHNGISIFCGIGERSREGEELYREMKEAGVLPNMVMIFGQMNEPPGARFRVGHAALTMAEYFRDDESRDVLLLIDNIFRFIQAGSEISGLMGQMPSRLGYQPTMGSELSSLEERIANTEDGAITSIQAVYVPADDFTDPAAVHTFSHLSASIVLSRQRASEGLYPSIDPLQSSSKMATAGIIGERHYNLAQEVRRTLAKYDDLKDIIAMLGLEQLNVDDRKLVGRARRLERFFTQPFFSTEQFSTMEGKLVSLDDALDGCERILADEFADYPESALYMIGAVDEVKINNKAAQHTKQQKEKNNGSTDVN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 1, ATP synthase F1 sector subunit beta 1, F-ATPase subunit beta 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL31_CLOPS
Sequence: MRQGIHPEYHHDTVVKCACGNTFTTGSVKPELKVEICSKCHPFFTGKQKIVDVGGRVDKFNKRFNLNK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: Y1031_LATSS
Sequence: MESWLFLAAILIVALLAKNQSLIIATAVVLVLKALPISEKVLPVIQAKGINWGVTVISVAILVPIATGQIGFKELISAFKTPAGFIAVGCGVLVAVLSAKGVGLLAASPEMTVALVFGTIMGVVFLKGIAAGPVIAAGITYTILTIFNLVPIH
What are the official names of this protein?
UPF0756 membrane protein LSA1031.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.