PharMolix/UniProtQA huggingface dataset:
Protein: CNDD2_ARATH
Sequence: MAPPFVFPQILRALEEDPEDNHRLFAQNPVDVTSLRPSDLEEFVKGVSFDLSDRELFCVEDQDVFDRVYSLVRSFFSLPPSCKCNLVESLRSNLSVLLPNVDSISRSVQDQEDDVPIIDRITSHRNALKIYTFFLLTVVMNEESHISSVETTKVAARGRKKQIIQSWNWEPQRGRMLNLIANSLEINLSLLFGSSDLDENYLSFIVKNSFTLFENATILKDAETKDALCRIIGASATKYHYIVQSCASIMHLIHKYDFAVVHIADAVARAESKYSDGTLAVTIIRDIGRTDPKAYVKDTAGADNVGRFLVELADRLPKLMSTNVGVLVPHFGGESYKIRNALVGVLGKLVAKAFNDVEGDMSSKSLRLRTKQAMLEILLERCRDVSAYTRSRVLQVWAELCEEHSVSIGLWNEVASLSAGRLEDKSAIVRKSALNLLIMMLQHNPFGPQLRIASFEATLEQYKRKLNELEPTEHASKESTSDGESCNGDGEIDDLHLETTTKIHQDSLSDSCQPENGEEISEKDVSVPDIGNVEQTKALIASLEAGLRFSKCMSASMPILVQLMASSSATDVENAILLLMRCKQFQIDGAEACLRKILPLAFSQDKSIYEAVENAFISIYIRKNPVDTAKQLLNLAIDSNIGDQAALEFIVNALVSKGEISSSTTSALWDFFCFNINGTTAEQSRGALSILCMAAKSSPRILGSHIQDIIDIGFGRWAKVEPLLARTACTVIQRFSEEDRKKLLLSSGSRLFGILESLITGNWLPENIYYATADKAISAIYMIHPTPETLASTIIKKSLSTVFDVVEQEEAQTDTENNKVDILTPVQVAKLSRFLFAVSHIAMNQLVYIESCIQKIRRQKTKKDKPAAESQNTEENLEATQENNGINAELGLAASDDALLDTLAERAEREIVSGGSVEKNLIGECATFLSKLCRNFSLLQKHPELQASAMLALCRFMIIDASFCESNLQLLFTVVENAPSEVVRSNCTLSLGDLAVRFPNLLEPWTENMYARLRDASVSVRKNAVLVLSHLILNDMMKVKGYIYEMAICIEDDVERISSLAKLFFHELSKKGSNPIYNLLPDILGQLSNRNLERESFCNVMQFLIGSIKKDKQMEALVEKLCNRFSGVTDGKQWEYISYSLSLLTFTEKGIKKLIESFKSYEHALAEDLVTENFRSIINKGKKFAKPELKACIEEFEEKINKFHMEKKEQEETARNAEVHREKTKTMESLAVLSKVKEEPVEEYDEGEGVSDSEIVDPSMEESGDNLVETESEEEPSDSEEEPDSAQCGTAIPRYLNQKTSGDNLIETEPEEEQSDSEPDSAQCGTTNPRSLNRKTSGDNLIETESEEEQSDSEEEPSDSEEEPDSAQCGTTNPRSLNQKTSGGEEGESESKSTESSSSIRRNLRSGSRS
What is the function of this protein?
Essential protein (PubMed:23929493).  Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes (By similarity).  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).  Required for fertility, growth and euchromatin organization, but not for sister chromatid cohesion (PubMed:23929493).  Necessary to maintain normal structural integrity of the meiotic chromosomes during the two nuclear divisions of gametogenesis, especially to maintain compaction of the centromeric repeats and 45S rDNA (PubMed:25065716).  Seems also involved in crossover formation during meiotic prophase I (PubMed:25065716).  Prevents centromeric and pericentromeric heterochromatin repeats association (PubMed:23929493).  Contributes to the induction of stress-responsive genes in response to stress treatment (PubMed:16856987).
What are the official names of this protein?
Condensin-1 complex subunit CAP-D2, Protein CHROMOSOME-ASSOCIATED POLYPEPTIDE D-2, AtCap-D2.
What is the protein family that this protein belongs to?
Belongs to the CND1 (condensin subunit 1) family.
What are the subcellular locations of this protein?
Chromosome. Nucleus. Note=Associates with the chromosomes throughout meiosis.
Protein: MIAB_SALG2
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWRLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGTFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRVLNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETNDDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKNIMELSGRTENNRVVNFEGTPEMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENELGVGFYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRP_PELPD
Sequence: MGEKLICNNKKAYHDYFIEEKMEAGLVLLGTEVKSLRAGKANLNDSFMLVRDGEAFLHNLHISPYEFGNRQNHQADRNRKLLLHRKQIDRLYGRIREQGYSIVPLRMYFKDGLVKVEIGLAKGKKLYDKREDMKKKDSQRELSQALKSKNRE
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SE1_MAIZE
Sequence: MIRPAPWVGAGHRGRGGEAGACTESLGSESGDVGCDAAEIDQFFPPAPAAGGPDDAGAEPCIPDLAAAAAAGKRRRGGFPPPMPRASGPLFLRAERRGGRLILTEVRADERERRVVFRAERDGGRLRLRFANDGDGPEAAGGGGGAGGGGGELCQVAAGRRGVQVGAVMMGAI
What is the function of this protein?
Involved in starch metabolism in endosperm (PubMed:31548423).  Acts as a modifier of SUGARY1 (SU1), an isoamylase starch-debranching enzyme involved in amylopectin biosynthesis in endosperm (PubMed:31548423).
What are the official names of this protein?
Protein SUGARY ENHANCER 1.
What is the protein family that this protein belongs to?
Belongs to the fantastic four family.
Protein: GDF8_PANPA
Sequence: MQKLQLCVYIYLFMLIVAGPVDLNENSEQKENVEKEGLCNACTWRQNTKSSRIEAIKIQILSKLRLETAPNISKDAIRQLLPKAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYNKVVKAQLWIYLRPVETPTTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLKQPESNLGIEIKALDENGHDLAVTFPGPGEDGLNPFLEVKVTDTPKRSRRDFGLDCDEHSTESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTHLVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS
What is the function of this protein?
Acts specifically as a negative regulator of skeletal muscle growth.
What are the official names of this protein?
Growth/differentiation factor 8, GDF-8, Myostatin.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: SECA_HAEIG
Sequence: MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKREAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAEKSSELYIAVNKLIPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDIKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAKFHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKRNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQRNYLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISNWLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMHHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHHVIMTLTRVRVRTQEEMEEAELARQEMATRINQNNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGSRVARQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: IINMP_SCHPO
Sequence: MESSRLFTLGLGNSDDGLKSTFGDKTVTCFYCNKKKEKIRDGTSTWTCSICEATNHIDEKGDILDYRPPTPTQDKGVGPFYAIRDFPSSSSFQSPFCEKCQMNQLIVNRMLADYLPDSSHPDYQAYEKALPEYKKSIEEKFPIVCSECYDSVQDQLDANDYEAKNQVLGYWLQKSKEQLNAKVPHHYPKASFVLWLLRGFGFSFFYLQSIVWHLYHSMIISLLPDGIRNLFLKAISYFLLDGSSSKIFYFNWLGFFVVFWNPYWYKMMDNPSWELFGRDQYIQCQALYLIIRLTCLYLLSCYESEILNLSSDTNLESDFLLRQIHAAFFFVTICFTWISISCLKPSPPPEVHLTGEILKPRKKRQESTSSVHRIGKESSDRKDGISGQNKLQQFATISILNNTNATSHLGNQSVRERAPEESPMTFLQKKMAALPTSSPVRPMLKPTLQLQNSPLSKLVPQEVGNKVNDSIHTTSNQPSKFSLNPSISLKGDNVIEKNLPFSVSTLKSTAKKDTGKAGDGQNREIQNEPVSLESHFSKSLALQNDPTEVIQVKNVLHRNRRNAKLLIAFTILFLVGLICGWRLNRFTMFIYYLCILVLATYYVMKHNFYPLRKVA
What is the function of this protein?
Inner nuclear membrane protein that specifically binds to heterochromatic regions and promotes the tethering of centromeric DNA to the SUN-KASH complex.  Couples centromeres to the nuclear envelope, thus contributing to their association with the microtubule organizing center attachment site and to the positioning of the nucleus at the cell center by microtubules.
What are the official names of this protein?
Integral inner nuclear membrane protein ima1.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: Y1546_AQUAE
Sequence: MEEKDLLEFAREVIREEIKGLERLLSSLDENFSKAVEILRNCEGKVILTGIGKSGHIARKISSTLSSTGTPSVFLHPAEALHGDMGLLDSKDALIAISNSGESTEVLYVLQYAKALNIPVIGITGNEKSSLAKYSDVVLKIPVDREACPFNLAPTVSSTVTLALGDAIAMTLMKLKGFSQEDFAKRHPAGALGRKLRLVKDLYHTGEEVPIVKEDTSMKEAIIEMTAKGFGATAVVNEEGKLVGIITDGDLRRFVNRGGSFENTRAKDVMTKNPKTIKPDELALKALRKMEDHNITVLIVVNEENEPIGILHMHDILKAELS
What are the official names of this protein?
Uncharacterized phosphosugar isomerase aq_1546.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GutQ/KpsF subfamily.
Protein: ISPG_SYNS9
Sequence: MTALDRRYDTQIHRRVTRTVMVGSVPIGSEHPIAVQSMINEDTLDIDGSVAGIIRLVDAGCEIVRVTTPSIGHAKAMGKIKAELSAKGCNVPLVADVHHNGTKIALEVAQHVDKVRINPGLFVFDKPDPNRQEFTESEFAEIGTRIRETFEPLVKLLREQNKALRIGVNHGSLAERMLFTYGDTPKGMVESAMEFVRICDDLDFHNIVISMKASRAPVMLSAYRLMADTMDQEGFNYPLHLGVTEAGDGDYGRIKSTAGIATLLAEGLGDTIRVSLTEAPEKEIPVCYSILQSLGLRKTMVEYIACPSCGRTLFNLEDVLHKVRNATSHLKGLDIAVMGCIVNGPGEMADADYGYVGKGPGIIALYRGREEIRKVPEKEGVQALIQLIQEDGLWVDPDETR
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: CH602_SYNAS
Sequence: MGAKLLQYDEEARKSILNGVNALADAVKVTLGPKGRNVIIDKSFGAPTVTKDGVTVAKEVELEDKFENMGAQMVREVASKTSDVAGDGTTTATILAQAIYREGAKTVAAGSNPMDVKRGIEKAVAAVVTELKNISKPTKDQKEIAQVGTISANNDETIGNIIAEAMGKVGKEGVITVEEAKGLETELEIVEGMQFDRGYLSPYFVTNPEKMEVSLEDALILIYEKKISGMKDLLPILEQIAKMGRPLLIIAEDIEGEALATLVVNKIRGTLHVAAVKAPGFGDRRKAMLEDIAILTGGTVISEDMGYKLENTRLEDLGRAKRIQIDKDNTTIIDGAGERAALEGRVKQIRAQIDETTSDYDREKLQERLAKLVGGVAVIKVGAATETEMKEKKARVEDALNATRAAVEEGIVPGGGVAYIRTLPILEALKLEGDEQVGVNIVRKALEEPLKMIAANAGMEGTIVVEKVKEQSGAFGFNARTEVYEDMIEAGVIDPTKVTRFALQNAASVASLMLTTQCMIAEKPEEKGAGMPGMPPGGGYPGMGM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_CAMJR
Sequence: MKHIEIYTDGSCLNNPGFGGWAYILRYKEYQKEGFGAEANTTNNRMELMAIIESLKALKEPCEISLFTDSNLMVQSINEWLEGWIKKDFKGKKNIDLWKEYIKVAKSHKIKAFWVKAHNGHLENERCDTLAREAALKIARENDEKH
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARCC_RHIME
Sequence: MRVVIALGGNALLKRGEPMTAEVQRQNIKIAAEAIAPIAAEHQIVVTHGNGPQVGLLALQGSAYKPEEAYPLDILGAETEGMIGYMLEQELGNVLPFEVPLATILTMVEVDGNDPGFQNPTKFVGPVYDASEAGELHQQKGWVFKQDGNKWRRVVASPIPRRIFELRPIQWLLDKGAVVICAGGGGIPTMYERGKERTLIGVEAVIDKDLCSALLARDIEADLLILATDAEAVFTGWGTPERKAIFKTNPRRLGEFSFPAGSMGPKVEAACHFVNATGRVAAIGALADIPAMVRAERGTIISSSFSDITWHVEVPIPGPASRPV
What are the official names of this protein?
Carbamate kinase.
What is the protein family that this protein belongs to?
Belongs to the carbamate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MU166_SCHPO
Sequence: MPRRAVLFRGNSFISFSSISSGNESSAHGDASLGQADKPLTVDVLDAWTTQFTKKQTRVFHEAYVSAYIDLQQKYARLERLQEQILNLERSLLNYKSLKSNSTTTVATVPSEKRYFFRRKPKTSSTTNSLSSSSSSVSHMNQDANPNSTVLTFTAVPYDSCLPAPDRHTPSSASSRASETGTTSPQSMRNQISLLYSKVDQVKTEIASAQAVMHDLLRTYPGSESLQQSTHTQF
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 166 protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes at the cell tip and barrier septum.
Protein: CD80_HUMAN
Sequence: MGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV
What is the function of this protein?
(Microbial infection) Acts as a receptor for adenovirus subgroup B.
What are the official names of this protein?
T-lymphocyte activation antigen CD80, Activation B7-1 antigen, BB1, CTLA-4 counter-receptor B7.1, B7.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NU4M_PIG
Sequence: MLKIIIPTTMLLPMTWMSKHNMIWINATVHSLLISLISLSLLNQLGENSLNFSLTFFSDSLSAPLLVLTTWLLPLMLMASQSHLSKETTTRKKLYITMLILLQLFLIMTFTATELILFYILFEATLVPTLIIITRWGNQTERLNAGLYFLFYTLAGSLPLLVALVYIQNTTGSLNFLIIHYWSHPLSNSWSNIFMWLACIMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRITTILNPLTNYMAYPFLMLSMWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAIMIQTPWSFMGATALMIAHGLTSSMLFCLANTNYERVHSRTMILARGLQTLLPLMATWWLMASLTNLALPPSINLIGELFIITASFSWSNITIILMGMNMMITALYSLYMLITTQRGKYTHHINNIKASFTRENALMALHILPLLLLTLNPKMILGPLY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: GLCT_STACT
Sequence: MSNYVIEKTLNNNVIICTDENQHHEVVLIGKGIGFNKKKGMELSDSVMIDKVYKLEQKKDQDHYKALVEIADDNVLQTIIEAMDIITHADRTVVDKDLMVALTDHILFAYKRIKQHQFIKNPFLIETKQLYSESYQIAVSVIEHLNKLLDIEFPEDEIGFIALHIASSKDDLSLHEVRLTNEIINKSILIMEHDLKYKIDTNSIQYQRFIRHIQFLIRRLQKGEIIQVNDEFGNMLKAHYPLCYNIAVKIIKMMQQHLDVEVYEAELIYLTLHINHFTQQNEKNTNV
What is the function of this protein?
Mediates positive regulation of the ptsG/glcA and glcB genes by functioning as an antiterminator factor of transcription via its interaction with the RNA-antiterminator (RAT) sequence located upstream of the ptsG/glcA gene.
What are the official names of this protein?
GlcA/glcB genes antiterminator, PtsG operon antiterminator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional antiterminator BglG family. GlcT subfamily.
Protein: ACCA_POLNS
Sequence: MKTTFLDFEQQIAELESKIEELRFVQDESSVDISDEIKMLAEKSLQLTKDVYANLTPWQVSQVARHPQRPYTLDYVGALFTDFHELHGDRTFADDQSIIGGLARFENQPCMVIGHQKGRDTKERALRNFGMSRPEGYRKAMRLMRLAEKFGIPVFTFVDTPGAFPGIDAEERNQSEAIGRNLYVQAELEVPIIATIIGEGGSGGALAIAMGDAVLMLQNSTYSVISPEGCASILWKTADKASEAAEQLGLTAQRLKALGLIDKIVAEPIGGAHRDYDGMMSNMRKALAESLKTFDGMKVDALLDRRHERLMSYGKFKEITAKS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TKN_ELECI
Sequence: QPSKDAFIGLM
What is the function of this protein?
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
What are the official names of this protein?
Eledoisin.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RU1C_FUSV7
Sequence: MPKFFCDYCDVYLTHDSMSVRKAHNSGRNHLRNVVDYYQQIGHEKAQSVIDSITSSYAAEGQAHANPMLPQNQPGQGFPPPPFGFPGGIPPPFPGMPGAPPGQFPQGMPPPPGGGRGMPPMPPFPPGPNGMPVPPNGLPFPPPGGFPFPPPGAPGAPGAPGASGGAPPPFPGLPGMPPPGQGFPPGGPPGFAPPGAGAPGHEKR
What is the function of this protein?
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome.  U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.  The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA.  Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
What are the official names of this protein?
U1 small nuclear ribonucleoprotein C, U1 snRNP C, U1-C, U1C.
What is the protein family that this protein belongs to?
Belongs to the U1 small nuclear ribonucleoprotein C family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDTH_CITK8
Sequence: MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAALMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCFLSGLGGTLFDPPRSALVVKLIRPEQRGRFFSLLMMQDSAGAVTGALLGSWLLQYDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVKIPVREGMGRVMADKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDIAGSPSAVKWMYAIEACLSLTLLYPIARWSEKRFRLEHRLMAGLLLMSLSMLPVGLVGNLQQLFTLICTFYIGSVIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDMGKALQQPELPWMMLGVIGIMTFLALGWQFSHKRTPRGMLEPGA
What are the official names of this protein?
Multidrug resistance protein MdtH.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtH (TC 2.A.1.2.21) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KATG_FLAJ1
Sequence: MENQSNDISKCPFHNGSMDNQAASGTKNNDWWPKQLKVNILRQNSSLSNPLSKDFDYAEAFKTLDLEAVKKDLHVLMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRVHDGRGGAGAGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLMILTGNVALESMGFKTFGFAGGRADVWEPDESVYWGSETTWLGGDERYNNGSDGVPKDHGVVSADDDADGKVHSRNLEKPLAAVQMGLIYVNPEGPDGNPDPILAAKDIRDTFGRMAMNDEETVALIAGGHTFGKTHGAASSDHVDKEPEAAGLELQGFGWKNSFGSGKGADAITSGLEVTWTKTPTQWSNNFFENLFAFEWELSKSPAGAHQWVAKNAEAIIPDAFDSTKKHLPTMLTTDLSLRLDPEYEKISRRFLENPDQFADAFSRAWFKLTHRDMGPRARYLGPDVPQEVLLWQDPIPEVNHKLIDENDIKQLKEKILNSGLSISQLVAAAWASASTFRGSDKRGGANGARVRLAPQKDWEVNNPAKLAQVLSKLETIQTEFNASQNDGKKVSLADLIVLAGSAGVEKAAKDAGSSVTVSFNPGRMDASAEETDVESFGYLEPKADGFRNYRKTKSAVSTEELLIDKANLLTLTAPELTVLLGGLRVLDINADGSKNGVFTHRPGQLTNDFFVNLLDMNTQWQAVSNDKELYAGNDRSTGQPKWIATRADLVFGSNSELRAVAEVYASTDANEKFVNDFIKAWTKVMNLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RL3_KLULA
Sequence: MSHRKYEAPRHGHLGFLPRKRAASVRGRVKSFPKDDQTKPVALTSFLGYKAGMSTIVRDLDRPGSKFHKREVVEAVTVVDTPPIVVVGVVGYVETPRGLRSLTTVWAEHLSDEVKRRFYKNWYKSKKKAFTKYSAKYAENGAQVDRELARIKKYASVVRVLVHTQVRKTPLSQKKAHLAEIQLNGGSVSDKVDWAKEHFEKTVAVDSVFEQNEMIDVVAVTKGHGFEGVTHRWGTKKLPRKTHRGLRKVACIGAWHPAHVMWSVARAGQRGYHHRTSINHKVYRVGKGDDEANAATEFDRTKKTITPMGGFVHYGAINNDFVILKGSIPGTRKRVVTLRKSLYTNTSRKALEEVTLKWIDTASKFGKGRFQTPAEKHAFLGTLKKDL
What are the official names of this protein?
60S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATOH8_DANRE
Sequence: MKNPHLNSPCKILNTVSGDKKMKRKAREPIKHVSEDHYPYFKLYKNPHLMAETLGDGSPQETHRSEIITSRDDSVRNDVLNTAVDMRINTITAAEVPDSKLRSVSEKTVNSKIVQASPQVSVLSAPQVFPLERVVLSQRAASQAPAGGSERAESPRKRAGEPSGVVTEIKAIQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAILRIACNYILSLAQLADLDYTPDHRNMSFRECVEQCTRTLQAEGRSKKRKE
What is the function of this protein?
Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity).  During development, is required for heart looping and swim bladder formation by acting in concert with GATA4 and ZFPM1 (PubMed:23836893).  During the development of both the retina and skeletal muscles is required for neural retinal cell through modulating PAX6 and NEUROG3 expression and myogenic differentiation (PubMed:20532172).
What are the official names of this protein?
Transcription factor atoh8, Atonal bHLH transcription factor 8, Protein atonal homolog 8.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Cytoplasm.
Protein: HISX_BURM1
Sequence: MSITIRKLDSTSEGFDAALRAVLAFEASEDEAIERSVAQILADVKSRGDAAVLEYTNRFDRLNADSVAALELPQDALQAALDGLEPKARAALEAAAARVRGYHEKQKIECGTHSWQYTESDGTVLGQKITPLDRVGLYVPGGKAAYPSSVLMNAIPARVAGVGEIVMVVPTPDGVKNDLVLAAALLGGVDRVFTIGGAQAVGALAYGTATVPAVDKICGPGNAYVASAKRRVFGTVGIDMIAGPSEILVLCDGTTDPSWVAMDLFSQAEHDELAQSILLCPDASFIERVEKAIAELLPSMPRQDVIRASLEGRGALIKVRDMTEACRIANDIAPEHLEISALEPQQWSQQIRHAGAIFLGRYTSESLGDYCAGPNHVLPTSRTARFSSPLGVYDFIKRSSLIEVSAEGAHTLGEIAAELAYGEGLQAHAKSAEFRMKG
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.