PharMolix/UniProtQA huggingface dataset:
Protein: INT4_DROME
Sequence: MALAIKKRVGTYVETVDGSPPVKKLRLQTLAADAKGGKSGKVGNVERKLTALNQLDAYVGNLPAGALVLPTGTPVASTGAPSTGVIGNPPAAATGAPPMTAANSRELLELLVKITDEISYEDVEMGELKEVASKIFQLYQLQERDSDTSIRVKLLELLSGLGCECATEQALTMIIDYFIFLLRKEVSQKVLAQGMMCLFRIGERRKHMLPISYKTQVAHLAKEQLRSGSAHTQKNAMLVIGRFATKMEGERHYVWKLAFYIDSQDSSVRAQALHALLTLGERGSQLPAVLYKRAVEAMKDDYECVRKEALQLVFMLGNRHPDYILPSDRQQEELRMIDAAFSKVCEALCDLSLQIRVLAAELLGGMTAVSREFLHQTLDKKLMSNLRRKRTAHERGARLVASGEWSSGKRWADDAPQEHLDAQSISIIASGACGALIHGLEDEFLEVRTAAVASMCKLALSRPDFAVTSLDFLVDMFNDEIEDVRLKAIYSLTAIAKHIVLREDQLEIMLGSLEDYSVDVREGLHLMLGACRVSTQTCLLMVVQKLLDVLAKYPQDRNSTYACMRKIGQKHPHLVMAVAVHLLYVHPFFETPERDVEDPAYLCVLILVFNAAEHLVPIISLLPTATHRHYAYLRDSMPNLVPQLPIEGASSASATHRIDSAMHQAGSSAEYLQMILSHIEEIFTMTDERLELLQTAQSNLQRLGSIDAGMYGTSNFLETFLAAQIQIEQMQRCASTQRSRVPLKESLAALIRNCLKLQHTFSGLNYGDILQVKQLRLRACALHLVLVVRDRSQSALGPCQMLLQTAGDISEFIKANTKDEEEKPPVVETDMPMKESVSRDAQPDSFTRQLLIKLDGISDPKPGRVFREILPLVQQAPPLALPPANDKIRRCVANILEPCPLQSQDNVIKVTAGLIAAVPFVAEIDNLLESQKADMRIKIKYPDQHMHTVVPKQSDFKPIMTEQGEHKTNVRLRTTILLSHSVWTESSLVEIQLCLAVRPGSELELCKPAKVLFAPKPVRRGI
What is the function of this protein?
Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:21078872, PubMed:23097424).  Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872, PubMed:23097424).  Essential for development (PubMed:21078872).  May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity).
What are the official names of this protein?
Integrator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CV024_HUMAN
Sequence: MTTQEDTTGLHQKTSLWTMSRPGAKKVMNSYFIAGCGPAVCYYAVSWLRQGFSINLTSFGRIPWPHAGVGTCPSPQSWISPFLQSHREHHYAKTSSHSQPSPQSLALCLAYSRCSINICQMTECISLASGCHQALREPGRSEESFWIPATPYISNIFSES
What are the official names of this protein?
Putative uncharacterized protein YWHAH-AS1, YWHAH antisense RNA 1.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MTND_LEPIN
Sequence: MATIVRQNGLTPIQETNEVKSFLKERGIDYDHWKVPHNASNLTDKEVLVDTEKEELLKKLDDRFETLKAKEGYQSRDLIVLHPNVSGLNEMLAKFDKVHYHTDEEVRYIVDGSGVFGFAFKDEKFLVHVYKDDFISVPRNTNHWFYLDDKKRIKAVRYFQDMSGWVPNYVEETNSLD
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: TWK12_CAEBR
Sequence: MTLFQKLQWFCQLIRLRAYYKFLLLIAYTLFGAWLFRFYELQADIKRRAIYGNDTNLIRRQLAERWIEMHDDAVLRNNSVLRRRRAAEAVDWLLGELNLSDHMREFSEDTPWTWTGAMFYAGQLYTTIGYGYPTAKTDEGRICTVLYALFGIPCFLMYLKAIGKTLSKRLKKIYKRVRRSAFGKFLLPTRVTATKDGFEDPDASAEERKRKPFPIPIAIILLIIWICFSASMFCQWEKTWDFPSAVYFFIVSISTVGLGDMLFRTPDMMVFNFLLILFGLALLSMCFELITDRIAKWKQKRFDEHIKKVQKMAFQVFEKDPFVEEAPPLGIRMAPNLMQIAATHVSEEKRGFFAELKDWFAGKVTDNVIQSKLEDTDDESDEDEALEEFESPQVATLTANDLVVCTNGGATRRVSKQSYAFSDVSNLSNSKIPPGNNYGQLLDRIKAMEKFKPKKGDLDSRMFAKFLENKKLAKILEQTELRELATVSCQTDLSGLVVQRRNPKGRHARIGSCSSQSTMSTFLPRNNSHAPDEDSVMSITFGDLKFDYITEPLIDEYHLRESNHSIFDFDDDEVVRIPQKMLVSRPGMPPPPPSRPSQLASPLRALLEKEQKYDEDPEIQLTPRRLASLTDVQARKVKLGYDENLQHARLVCGLLPQDFDSPSTSTSTSMIDSGYDLSKRDAPVNIV
What are the official names of this protein?
TWiK family of potassium channels protein 12.
What is the protein family that this protein belongs to?
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: M126_CHICK
Sequence: MSKGCQTQGPLSELEKAIDVIIDVFHQYSRREGDKDTLTRKELKLLIEKQLANYLKHVKNQVSIDQIFKDLDNNKDQQLSFGEVMLLIIRVTVATHEHLHFCEDHQQQHQHQHQHQHNH
What are the official names of this protein?
Protein MRP-126.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
Protein: CARB_BUCAI
Sequence: MPKSTDIKSILILGAGPIVIGQACEFDYSGTQACKALKEEGYRIILLNSNPATIMTDPDMADATYVEPIHWEIVEKIIQKEKPDALLPTMGGQTALNCALELDHKGILKKYGVQIIGATVDAIKKAENRKLFEHSMKKLNLETAKCGIAHNIQEAFLVLNNVGFPCIIRPSFTMGGHGGGIAYNHEEFEKICERGLELSPSTELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENLDPMGIHTGDSITVAPAQTLTDKEYQVMRNASMSILREIGVETGGSNVQFAINPKNGRMIVIEMNPRVSRSSALASKATGFPIAKIAAKLAIGYTLDELANDITGTNTTASFEPSIDYIVTKIPRFNFEKFPGCDDRLTTQMKSVGEVMAIGRTFQESIQKAIRGLEVGASGFDSKISSRDSEYLIKIRRELKDAGSERIWYIGDAFRYGMSINDVFDLTSIDPWFLVQIKEIILLEKKIIKNGFIGLKYDFFYFLKRKGFSDQRIAILTNKNESEIRQLRYKLNLHPVYKRIDTCSAEFSTETAYMYSTWEDECESHPSKNNKKIIILGGGPNRIGQGIEFDYCCVHAAQALREDGFEAIMVNCNPETVSTDYDISDRLYFEPITLENVLEIVRIEKPKGVIIQYGGQTPLKLAHEFEKEGVPIIGTSPDSIDTAENRYRFQKTVNKLRLQQPLNATVLTLDEAYKKADIIGYPIMVRPSYVLGGRAMEIVYEPYGLENYFKTTLKKNNTTPILLDQYLDYATEVDVDAICDGETVLIGGIMEHIEQAGVHSGDSACSLPAYTLTSKVQNEIRRQVKKLAFELSVKGLMNIQFAIKNNKIYIIEVNPRAARTVPFVSKAIGLALAKISVRVMCGKTLLEQGFIKEIIPPYFSVKEAVLPFDKFQGVDPILGPEMRSTGEVMGIGKNFSEAFSKSMLGAHTNMKKSGRVLLSVRNNDKNNIINLAVKLKKLGFKIDATKGTSVALKKSGISSRLVNKVHEGRPHIQDRLKNGEYSYIVNTTSCYQGIKDSKLICRSALQYKVHYDTTVNGAFATVMALNENPIKNIETLQKIHKKIQLFYTKK
What are the official names of this protein?
Carbamoyl-phosphate synthase large chain, Carbamoyl-phosphate synthetase ammonia chain.
What is the protein family that this protein belongs to?
Belongs to the CarB family.
Protein: PANB_ALIFM
Sequence: MKKISIHDLMKWKQEGKKFATVTAYDASFAQLFEQQEVPVLLVGDSLGMVLQGKSDTLPVTTEEIAYHTRCVRAGSPNSLVMADMPFMSYATPEQACENAGKLMQAGANMVKIEGGEWIAETVRILAERAVPVCAHLGLTPQSVNIFGGFRIQGRDEAKAEQMVKDALTLEAAGAQIILLECVPASLAERITKACTVPVIGIGAGNATDGQILVMHDMFGISANYMPKFSKNFLAETGDMRKAVTKYIQDVEQGTFPAAEHTFN
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_STRP3
Sequence: MANHRIDRVGMEIKREVNDILQKKVRDPRVQGVTITEVQMQGDLSLAKVYYTIMSDLASDNQKAQTGLEKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYGNKIDQLLRDLDNKS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPH2_DANRE
Sequence: MTDAFSSSSEAVLQRSVTSTHSFHPSGDLLLLYQTPETCRFITSNHFKKVALQFPDELLPDAVRVSAEIEDKTKAKTYILGDTSYGSCCVDEVAAEHVGADCIVHYGSSCLSPCRRLPLLYVFGKRPIDVHQCASSFKELYPNLQSHIIVLFDVTYSHAIDDLRTLLCDVYPNVVVSRLKTDHSCGAELIQDSCVDLQSNDDGVIFKFGRQFRIKEGQTVNDYSIFYIGQEGLTLTNFMMSWNNCVFSSFNPETSTGRVESVQINKALMKRYYAIERAKDASVVGILVGTLGVANYLIIIEQLKDTIQRAGKKSYMFAMGKINVPKLANFLEIDIYVLVACPENSLLDSSEFYRPVVTPFEMELACNKHREWTGEYVTDFRELLPGGSSHVGFPEPSQSATEEETTDVSLITGALRSCSTNSSEMMHNSETSSLVLRNQTLTVANTNAAASFLAGRSWQGLEPKLGQTPVVKAVKGQRGIAIAYEEEGNEDASTQQKL
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2 (By similarity).  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
Protein: CATC_ACIAD
Sequence: MLFQVRMDVHLPVSMPTDQANQIKSVEKAYSQELQRQGKWRHIWRITGQYSNISIFDVESNEELHTILQGLPLYPYMKIEVMALNRHPSSVRDDDS
What are the official names of this protein?
Muconolactone Delta-isomerase, MIase.
What is the protein family that this protein belongs to?
Belongs to the muconolactone Delta-isomerase family.
Protein: DAPB_BLOPB
Sequence: MSDTPLRIAVTGVTGRMGKEIVTCIVKEEKQFSQEIVLGAAITRLNTNICGMDAGILINTDALGIEITDNLESIKDNFDVLVDFTAPDISIEYLKFCVNNNKNIVIGTTGFNQIHKNIILNASHKIGIVFSSNFSIGVALISKLLHKITQVIGNTSDISIIETHHNRKRDIPSGTSLTMQNIIVNALRSIHSNRIIDSNLDSTTYSPASSYKDILIHSIRAGDVVGEHTVLFAGPGERLEITHKASDRLIFAHGALRAAFWVGRDKIGLFDISDILEMDTLL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANO3_MOUSE
Sequence: MGTFNLWTDYLGLARLVGALHKEEELDVRLDPKPEPKPSSESQQASKESSAAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHAHTRRFCPLTSQGYTSVYCYTTRNSAGKKLTRPDKAKTQDAGHRLGGEAAAGVYAGSKSGRKPPGPSPSACCPSTTA
What is the function of this protein?
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase.  Affects cell proliferation probably by repressing translation of specific mRNAs.  Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways.  Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
What are the official names of this protein?
Nanos homolog 3, NOS-3.
What is the protein family that this protein belongs to?
Belongs to the nanos family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body. Note=Co-localizes with PUM2, EIF2S1 and TIAL1 in the stress granules. Co-localizes with DCP1A in the P-body.
Protein: RN112_MOUSE
Sequence: MPRPVLSVTAFCHRLGKRESKRSFMGNSSNSWVLPREEAQGWMGQAVQGGTRTSRSHASFPKLELGLGHRPSPTREPPTCSICLERLREPISLDCGHDFCIRCFSTHRIPGCELPCCPECRKICKQRKGLRSLGERMKLLPQRPLPPALQETCAVRAERLLLVRINASGGLILRMGAINRCLKHPLARDTPVCLLAVLGEQHSGKSFLLDHLLSGLPSLESGDSGRPRAEGSLPGIRWGANGLTRGIWMWSHPFLLGKEGKKVAVFLVDTGDVMSPELSKETRVKLCALTMMLSSYQILNTSQELKDTDLGYLEMFVHVAEVMGKHYGMVPIQHLDLLVRDSSHHNKSGQGHVGDILQKLSGKYPKVQELLLGKRARCYLLPAPERQWVNKDQASPRGNTEDDFSHHFRAYILDVLSTAPQHAKSRCQGYWSEGRAVARGDRRLLTGQQLAQEIKNLSGWMGKTGPSFNSPDEMAAQLHDLRKVEAAKKEFEEYVRQQDIATKRIFSALRVLPDTMRNLLSTQKDAILARHGVALLCKEREQTLEALEAELQAEAKAFMDSYTMRFCGHLAAVGGAVGAGLMGLAGGVVGAGMAAAALAAEAGMVAAGAAVGATGAAVVGGGVGAGLAATVGCMEKEEDERVQGGDREPLLQEE
What is the function of this protein?
E3 ubiquitin-protein ligase that plays an important role in neuronal differentiation, including neurogenesis and gliogenesis, during brain development.  During embryonic development initiates neuronal differentiation by inducing cell cycle arrest at the G0/G1 phase through up-regulation of cell-cycle regulatory proteins (PubMed:21566658, PubMed:28684796).  Plays a role not only in the fetal period during the development of the nervous system, but also in the adult brain, where it is involved in the maintenance of neural functions and protection of the nervous tissue cells from oxidative stress-induced damage (PubMed:27918959, PubMed:26792191, PubMed:26951452).  Exhibits GTPase and E3 ubiquitin-protein ligase activities.  Regulates dendritic spine density and synaptic neurotransmission; its ability to hydrolyze GTP is involved in the maintenance of dendritic spine density (PubMed:26212327).
What are the official names of this protein?
RING finger protein 112, Brain finger protein, Neurolastin, Zinc finger protein 179.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Membrane; Peripheral membrane protein. Cytoplasm. Nucleus. Nucleus, nuclear body. Nucleus, nucleoplasm. Endosome. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Postsynaptic density. Perikaryon. Cell projection, neuron projection. Note=Predominantly in the nucleus, but some amounts were also found in the cytoplasm (PubMed:9806830, PubMed:24359566). Oxidative stress stimulates its shuttling from the cytoplasm into the nucleus (PubMed:27918959). Recruited to nuclear bodies via its interaction with ZBTB16 (PubMed:24359566). Localizes to the cell soma and neuritis and only slightly to the nucleus in the neurons of most brain areas (PubMed:26951452).
Protein: GRPE_PROM0
Sequence: MIENQSDNIDNKEIDVSIQDNAPEDKSSMQNSTTENDELSSQKTEEINTEELKNTISNNDARLEQLEKEHETLKNQYVRISADFDNFRKRQSRDQDDLKIQLVSKTLTAILPIVDNFERARQQLKPESEEAQALHRSYQGLYKQLVEVLKQQGVSPMRVVGQQFDPNLHEAVLREPSEEFEEDFIIEELQRGYHLEGKVLRHALAKVSMGPGKQKSQQEVEKDTVEGDVDSDANTSEDV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_WIGBR
Sequence: MLILGIETSCDDTGAAIYDLEKGLIIHKVISQNNIHSKYGGVVPEKSSKYHLKNIQPLVENIFKNSNISLSKIDGIAYTAGPGLVGSLIIGATFACSLAYTLQIPSIAINHLEGHLLTPMIKYKRPKFPFLGLIISGAHTQFVLAEDIGKYKIIGDCLDDALGEAFDKVAKLLGIKYPGGKKLSIIAKQGNSKRFFFPRPMTKKPGINFSFSGLKTYAKNLVSSFSKIDNQTKCDIARAFEDSIIDTVIIKCKRALDITNSKILLISGGVSANEPLRKNLRNLMKSRNGKLFFSKKSLCTDNAAMIAYVGSIRFKKNKTKDLSVLINPKWSLEDISRLEN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_EHRCJ
Sequence: MSKSDYYELLGVSKNATSEEIKKAYRKMALKYHPDTNPGNKEAEEKFKELSEAYDVLIDQDKRAAYDKYGHNAFDGAAGRGGFDFNSGFSGDFSDIFNDLFGGGFGSRGGRGSSRRSEGAAGSDLRFDVEITLEDSFNGKKVPISYVTYVKCSSCSGSGSEGSAKSVQCNTCHGAGSVRTQQGFFTIERTCHVCNGEGEIIQNKCKKCSGSGRVRDEVNLLVTIPKGIESGNKIRLNGKGEAGYRGARSGDLYVYSNIQKHKFFTRSGPDLYCTVPIKMTLAALGGHIEMPSIDGTWTKVKVPEGSQSGDKLRLKEKGMPVINSSKRGDMYIQITVETPVKLTKKQKELLQKFDDEPNVDCNPQSTGFFQKVKSFWKDIRSN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSH1_MEDTR
Sequence: MTTIFRLASSSSPSLRHDATPHNFHIRKTSISNTFSFSSKNSLSFKRILTSGGSRRFIVAASPPTEDAVVATEPLTKQDLIDYLASGCKTKDKWRIGTEHEKFGFELGSLRPMKYEQISELLNGIAERFDWDKVMEGDNIIGLKQGKQSISLEPGGQFELSGAPLETLHQTCAEVNSHLYQVKAVAEEMGIGFLGIGFQPKWERKDIPMMPKGRYEIMKKYMPKVGSLGLDMMFRTCTVQVNLDFSSEADMIRKFRAGLALQPIATALFANSPFTDGKPNGFVSMRSHIWTDTDKDRTGMLPFVFDDSFGFEQYVDFALDVPMYFVYRKKKYIDCTGMTFRDFLAGKLPCIPGELPTLNDWENHLTTIFPEVRLKRYLEMRGADGGPWRRLCALPAFWVGILYDEVSLQRVLDMTADWTLEEREMLRNKVTVTGLKTPFRDGLLKHVAEEVLELAKDGLERRGFKESGFLNAVAEVVRTGVTPAERLLELYHGKWEQSVDHVFDELLY
What are the official names of this protein?
Glutamate--cysteine ligase, chloroplastic, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the carboxylate-amine ligase family. Glutamate--cysteine ligase type 2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NRDR_VIBVY
Sequence: MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELLMPKVIKSNGNREPFNEDKMVGGIQRALEKRPVSADAIELAISMIKSKLRATGEREVPSKMIGNLVMEQLKHLDKVAYIRFASVYRSFEDIREFGEEIARLED
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RK16_GUITH
Sequence: MLSPKRTKFRKPHRGRLRGIATRGNTLIFGDYGLQALEPIWLTSRQIEATRRTITRQVKRVGRLWIRVFPDKSISAKPPETRMGAGKGAPEYWVAVIKPGHILFEINGVSQDLRYLAFKNASYKLPIKTKFISR
What are the official names of this protein?
50S ribosomal protein L16, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FAIM1_MOUSE
Sequence: MTDLVAVWDVALSDGVHKIEFEHGTTSGKRVVYVDGKEEIRREWMFKLVGKETFFVGAAKTKATINIDAISGFAYEYTLEIDGKSLKKYMENRSKTTSTWVLRLDGEDLRVVLEKDTMDVWCNGQKMETAGEFVDDGTETHFSVGNHGCYIKAVSSGKRKEGIIHTLIVDNREIPELTQ
What is the function of this protein?
Plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.
What are the official names of this protein?
Fas apoptotic inhibitory molecule 1.
What is the protein family that this protein belongs to?
Belongs to the FAIM1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VAPB5_ARCFU
Sequence: MPKIIEAIYENGVFKPLQKVNFRPGSKVRIVIQEDKKEILRKYKGVFGKAEVEELREYEGEVML
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC5 (Potential).
What are the official names of this protein?
Putative antitoxin VapB5.
What is the protein family that this protein belongs to?
Belongs to the UPF0165 family.
Protein: DPO4_CUTAK
Sequence: MRSTASILHLDMDAFFASVEQRDKPSLVGKAVIVGGVGGRGVVATASYEARKFGVHSAMAGSQARRLAPNAAFLSGRFESYRESSKVVMATLRELSPLVEPLSLDEAFVDLEAGDVDVENLDALQQVAVELRARVAERTEGLSCSVGIGSSKFMAKVASEMAKPQRGHTDQIALIAPGTEADTIAPLSARAIPGVGPVTAERLEKLGLRTIADVRAARESELVHELGHASGASLVALSRARDDRPVVASRIAKSISVEDTFEHDLTHREECRQIVERHAGLVCGRLKKSGQFARTVTLKAKMADFTVWSRSVTLTGATDSPERISQLAVRMLDSLDLREGVRLLGVGVSNFATSAQEELFVVDDEGRLLDEPEVTEEITPIQPGPFGRRRSFDGRNWPPGVDLIHDEYGRGWVWGSGHGIVTCRFEYRGSEIGRVKSVPQDDEALHPAHPLPLAWQPPQEDVPSE
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_ECO45
Sequence: MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRUA_LEGPC
Sequence: MRIALVVEYDGSQYHGWQAQTGLHTIQQAVEFALSKVADSSISVVCAGRTDTGVHATNQVIHFDCEKDRSIRAWIHGANTFLPKDICVKWGKEMPENFHARYSAVSRRYRYVIYNGAIRPGLLRGNVTWQYRQLDHRLMQQGGQCLLGENDFTSFRSVECQSNTPMRNIHQLQVTRHGDLVVLDITANAFLHHMVRNIAGVLIAVGSGKHPVGWVKDVLNAKDRKLGAETAPSYGLYLVQVTYPKEFGLLQNNPGPLFLWEK
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GLGA1_TRIV2
Sequence: MYIVQIASECAPVIKAGGLGDVVYGLSRELEIRGNCVELILPKYDCMRYDHIWGLHEAYLNLWVPWFGAAIHCTVYCGWVHGRVCFFIEPHSEDNFFNRGCYYGCDDDDMRFAFFSKAALEFLHQSNKRPDIIHCHDWQTGLVPVMLYEIYKYHGMDTQRVCYTIHNFKHQGIGGVKTLWATGLNREAYYFQNDKLQDDFNPFALNYMKGGIVYSNAVTTVSPNHALEAQYTDVGCGLGHTLYQHKDKFSGILNGIDYDFWNPEIDRYIPYNYNQEDFEQKLYNKKALRERLLLQAADKPIIAYIGRLDNQKGVHLVHHAIYHSLNKGAQFVLLGSATEAGINAHFRHEKQFLNNNPDVHLELGFNEELSHLIYAGADMIVVPSNYEPCGLTQMIGLKYGTVPIVRGVGGLVNTVFDRDYDQNLPPEKRNGYVFYQSDNQALESAMNRAIDLWYQSPEKFQQLAIQGMKYDYSWNNPGKEYLDIYEWIKYKW
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase 1, Starch [bacterial glycogen] synthase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.