PharMolix/UniProtQA huggingface dataset:
Protein: CBPS1_DICDI
Sequence: MIFKFFFIFFLIILVIKISESVDSTVNVHLIKSRTELAYSFKESLSFKTISFDDESNKIDYDEFLKFHNFLQNKFPIIHRVLKRTVINKYSLLFEWTGSDKTLKPLLLNSHYDVVPVTESEWTFNPWGEIRNDNIYGRGSIDNKVIVMATMESIEAILANNYTQPIRTIYLCFGHDEELGGLNGHRMIARHFRENLVRAEAIFDEGCPFLASNFVPGFHDIIAGVGVFEKGYLFYKLTSKVNSFTHSAIPPKESAIGILSKALAKIESNPFAPIENIEKKNQLLQLFNGETIKSNPFLDAMTKTTTALSMIHAGTKPNIIPTTASAWVSHRIINGNSIEYVKSRILDLINDTRITMEIEGFLEPSPISSPFTTAYQILKQTIYQQFGGYNVKVVPTQLMANTDTRHYWDITDNIYRFMPIVGNFMDFVSIHGSNEKISIDDYIKTIHFYKKLILNFQPFSNSSNSNYINKNLKINDYCPNSIYSK
What are the official names of this protein?
Probable carboxypeptidase S-like 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Secreted.
Protein: DNAJ_BACC3
Sequence: MSKRDYYEVLGLSKGASKDEIKKAYRRLAKKYHPDVSKEENAIEKFKEVQEAYEVLSDDQKRAQYDQFGHAGANQGFGGFGGGGDFGGGFGFEDIFSSFFGGGGGRRRDPNAPRQGADLQYQVTLDFEEAIFGKELNVEIPVEDPCDTCKGSGAKPGTSKETCKHCSGSGQVSVEQNTPFGRIVNRQACSHCSGTGQMIKEKCTTCHGSGKVRKRKKINVKIPAGIDNGQQIRVSGKGEAGVNGGPAGDLYVVVHVRSHEFFEREGDHIICEMPLTFAQMALGAEVEVPTVHGKVKLKIPAGTQTGTEFRLKGKGAPNVRGYGQGDQYVVVRVVVPTKLTSHQKDLLREFAGQEEQDDSLFGKLKRAFKGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HDGR2_DANRE
Sequence: MPHNFRPGDLVFAKMKGYPHWPARIEDVADGAVKPPPNKIPIFFFGTHETAFLAPKDLFAYEKNQERFGKPNKRKGFNEGLWEIQNNPHASYNTPAAASSSDSEDNQPAAASDAEEEEEAVVPRKAETGSDDSDSGSEDQKKPAVKRKAPALKRPPVKKARASSSDRDGEESGSPSEPEPSPSSDSDSGKNSDQDFTPQKESGGRGGKKPAGRGRRKKASSGSDSDSGSQSDQKAARSDSEDEKPRPAASGSESQSGSKSDSDSEPPPPPPPTRKAPQGRKKAEKPPPKPRARKPKPAPERAPSSSSDSDSDSDTDRVSEWKKRDEERRKELEERRKREEAEELRRLREREKEEEEKRKKDKETKVRRGSSSSGSSSSDDEVDDHPLKKSKKPPPPPIPAPSDSDSPPPSELKKKKESQKGRQKKEKEVKEKKERPVKEKKPQRSEEKHKAKPKAEKPKRKPVRPPEKKVEKKKEPSPEEKLQKLHTDIKFALKVDNPDIEKCLQALDELSSVQVTTHILQKNADVIATLKKIRRYKASNAVMEKATAVYNKLKLQFIGKIETGKPKPNEKNQEEQDAQNTDDSKPVNGESEGERKDVSESESNSKPTDQDNPDENKSPNGIRPDPDEPADQLNDSTEADPTADADVKEDSREQDEQMSSES
What is the function of this protein?
May act as a regulator of myogenesis (By similarity).  Promotes the repair of DNA double-strand breaks (DSBs) through the homologous recombination pathway by facilitating the recruitment of the DNA endonuclease RBBP8 to the DSBs (By similarity).
What are the official names of this protein?
Hepatoma-derived growth factor-related protein 2, HRP-2.
What is the protein family that this protein belongs to?
Belongs to the HDGF family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TF212_SCHPO
Sequence: MSYANYRYMKARAKRWRPENLDGIQTSDEHLINLFAKILSKHVPEIGKFDPNKDVESYISKLDQHFTEYPSLFPNEHTKRQYTLNHLEELEQQFAERMFSENGSLTWQELLRQTGKVQGSNKGDRLTKTFEGFRNQLDKVQFIRKLMSKANVDDFHTRLFILWMLPYSLRKLKERNYWKSEISEIYDFLEDKRTASYGKTHKRFQPQNKNLGKESLSKKNNTTNSRNLRKTNVSRIEYSSNKFLNHTRKRYEMVLQAELPDFKCSIPCLIDTGAQANIITEETVRAHKLPTRPWSKSVIYGGVYPNKINRKTIKLNISLNGISIKTEFLVVKKFSHPAAISFTTLYDNNIEISSSKHTLSQMNKVSNIVKEPELPDIYKEFKDITAETNTEKLPKPIKGLEFEVELTQENYRLPIRNYPLPPGKMQAMNDEINQGLKSGIIRESKAINACPVMFVPKKEGTLRMVVDYKPLNKYVKPNIYPLPLIEQLLAKIQGSTIFTKLDLKSAYHLIRVRKGDEHKLAFRCPRGVFEYLVMPYGISTAPAHFQYFINTILGEAKESHVVCYMDDILIHSKSESEHVKHVKDVLQKLKNANLIINQAKCEFHQSQVKFIGYHISEKGFTPCQENIDKVLQWKQPKNRKELRQFLGSVNYLRKFIPKTSQLTHPLNNLLKKDVRWKWTPTQTQAIENIKQCLVSPPVLRHFDFSKKILLETDASDVAVGAVLSQKHDDDKYYPVGYYSAKMSKAQLNYSVSDKEMLAIIKSLKHWRHYLESTIEPFKILTDHRNLIGRITNESEPENKRLARWQLFLQDFNFEINYRPGSANHIADALSRIVDETEPIPKDSEDNSINFVNQISITDDFKNQVVTEYTNDTKLLNLLNNEDKRVEENIQLKDGLLINSKDQILLPNDTQLTRTIIKKYHEEGKLIHPGIELLTNIILRRFTWKGIRKQIQEYVQNCHTCQINKSRNHKPYGPLQPIPPSERPWESLSMDFITALPESSGYNALFVVVDRFSKMAILVPCTKSITAEQTARMFDQRVIAYFGNPKEIIADNDHIFTSQTWKDFAHKYNFVMKFSLPYRPQTDGQTERTNQTVEKLLRCVCSTHPNTWVDHISLVQQSYNNAIHSATQMTPFEIVHRYSPALSPLELPSFSDKTDENSQETIQVFQTVKEHLNTNNIKMKKYFDMKIQEIEEFQPGDLVMVKRTKTGFLHKSNKLAPSFAGPFYVLQKSGPNNYELDLPDSIKHMFSSTFHVSHLEKYRHNSELNYATIDESDIGTILHILEHKNREQVLYLNVKYISNLNPSTIMSGWTTLATALQADKAIVNDYIKNNNLNI
What are the official names of this protein?
Transposon Tf2-12 polyprotein, Retrotransposable element Tf2 155 kDa protein.
Protein: RL13_GLOC7
Sequence: MEKTTLPNLETLDKQWYVIDAAGQRLGRLASEIAMILRGKNKPTYTPHLDTGDFVIVINAEKVIVTGKKSQQKVYHRHSGRPGGMKVETFEKLQARLPERIVEKAVKGMLPKNSLGRQLFTKLKVYSGSNHPHQAQKPETLTINTIPGGNN
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RL30_NANEQ
Sequence: MALYAIFRVRGRVDVRKDIEDTLKLLRVHRKNYLSIMPKTESIEGMIQKAKDYITWGEIDEKTLAELLKKRGRISRRKKLTLEYIKEKGFNSFEELAKALIEGKVTLKELGIKPFFRLRPPSKGYGKKGIKKHFNEGGALGYRGEKINDLILRAI
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TPPA_ARATH
Sequence: MDMKSGHSSPVMTDSPPISNSRLTIRQNRLPYSSAAATAISQNNNLLLTVPRKKTGILDDVKSNGWLDAMKSSSPPPTILNKDNLSNDATDMTYREWMQLKYPSALTSFEKIMSFAKGKRIALFLDYDGTLSPIVEEPDCAYMSSAMRSAVQNVAKYFPTAIISGRSRDKVYEFVNLSELYYAGSHGMDIMSPAGESLNHEHSRTVSVYEQGKDVNLFQPASEFLPMIDKVLCSLIESTKDIKGVKVEDNKFCISVHYRNVEEKNWTLVAQCVDDVIRTYPKLRLTHGRKVLEIRPVIDWDKGKAVTFLLESLGLNNCEDVLPIYVGDDRTDEDAFKVLRDGPNHGYGILVSAVPKDSNAFYSLRDPSEVMEFLKSLVTWKRSMG
What is the function of this protein?
Removes the phosphate from trehalose 6-phosphate to produce free trehalose.  Trehalose accumulation in plant may improve abiotic stress tolerance.
What are the official names of this protein?
Trehalose-phosphate phosphatase A, AtTPPA, Trehalose 6-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the trehalose phosphatase family.
Protein: PER16_ARATH
Sequence: MKNQSSFSIVALLLIFFSSSVFAQLQTNFYRKSCPNVETIVRNAVRQKFQQTFVTAPATLRLFFHDCFVRGCDASILLASPSEKDHPDDKSLAGDGFDTVAKAKQALDRDPNCRNKVSCADILALATRDVVVLTGGPNYPVELGRRDGRLSTVASVQHSLPQPSFKLDQLNTMFARHGLSQTDMIALSGAHTIGFAHCGKFSKRIYNFSPKRPIDPTLNIRYALQLRQMCPIRVDLRIAINMDPTSPNTFDNAYFKNLQKGMGLFTSDQVLFSDERSRSTVNSFASSEATFRQAFISAITKLGRVGVKTGNAGEIRRDCSRVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 16, Atperox P16, ATP22a.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL27_MACFA
Sequence: MGKFMKPGKVVLVLAGRYSGRKAVIVKNIDDGTSDRPYSHALVAGIDRYPRKVTAAMGKKKIAKRSKIKSFVKVYNYNHLMPTRYSVDIPLDKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKWFFQKLRF
What is the function of this protein?
Component of the large ribosomal subunit (By similarity).  Required for proper rRNA processing and maturation of 28S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
60S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL27 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Rough endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: OBG_KORVE
Sequence: MFVDEAKIRVKAGNGGNGIVAFRREKFVPRGGPWGGDGGRGGDVIMESSERHNTLVHFRFNPEYKAERGRHGEGANKTGREGVDVLLKVPVGTLVYDDETGELLHEFVHPDERIIIARGGRGGRGNAQFATPTHQAPRESEDGKIGDEKFLRLELKLLADVGLVGYPNAGKSTLISRISSARPKIADYPFTTLQPNLGVVVVGEMPHEQSYVVADIPGLIEGASLGAGLGMQFLRHVERTRLIAHLVDVSDASGRPDPVQDYKVITKELASFGSGIEKKPTIIVATKIDVANPDKLKKLTTFAKRSKKAFFAISAVTGEGIEPLKWEMAKRVEAIRAKAQDPVEEADEIEAPKKKRRAPARKSVR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIR_ECO27
Sequence: MPIGNLGNNVNGNHLIPPAPPLPSQTDGAARGGTGHLISSTGALGSRSLFSPLRNSMADSVDSRDIPGLPTNPSRLAAATSETCLLGGFEVLHDKGPLDILNTQIGPSAFRVEVQADGTHAAIGEKNGLEVSVTLSPQEWSSLQSIDTEGKNRFVFTGGRGGSGHPMVTVASDIAEARTKILAKLDPDNHGGRQPKDVDTRSVGVGSASGIDDGVVSETHTSTTNSSVRSDPKFWVSVGAIAAGLAGLAATGIAQALALTPEPDDPTTTDPDQAANAAESATKDQLTQEAFKNPENQKVNIDANGNAIPSGELKDDIVEQIAQQAKEAGEVARQQAVESNAQAQQRYEDQHARRQEELQLSSGIGYGLSSALIVAGGIGAGVTTALHRRNQPAEQTTTTTTHTVVQQQTGGNTPAQGGTDATRAEDASLNRRDSQGSVASTHWSDSSSEVVNPYAEVGGARNSLSAHQPEEHIYDEVAADPGYSVIQNFSGSGPVTGRLIGTPGQGIQSTYALLANSGGLRLGMGGLTSGGESAVSSVNAAPTPGPVRFV
What is the function of this protein?
Multifunctional protein that is required for efficient pedestal formation in host epithelial cells during infection.  The extracellular region acts as a receptor for bacterial intimin, allowing the bacterium to attach tightly to the host-cell surface.  Simultaneously, the intracellular region initiates a signaling cascade in the host cell, which leads to actin polymerization and formation of actin pedestals at the sites of bacterial adhesion.  In strain E2348/69, acts mainly via the host adaptor proteins NCK1 and NCK2.  Once clustered and phosphorylated at Tyr-474, Tir binds to NCK proteins, which in turn bind and activate host WASL/N-WASP, leading to actin polymerization.  Can also trigger an inefficient, NCK-independent pedestal formation.  This pathway involves phosphorylation of Tyr-454 and probably a putative host adaptor.  Acts also via direct binding to the host cytoskeletal protein alpha-actinin in a NCK- and phosphotyrosine-independent manner.  This interaction may stabilize the pedestal, but is not essential for its formation.
What are the official names of this protein?
Translocated intimin receptor Tir, Secreted effector protein Tir.
What is the protein family that this protein belongs to?
Belongs to the Tir receptor family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane; Multi-pass membrane protein. Note=Secreted via the type III secretion system (TTSS). Released into the host cytoplasm via TTSS and then independently inserts into the plasma membrane from a cytoplasmic location. In host cells, localizes to the tip of the actin pedestal.
Protein: IF2_RICPR
Sequence: MTDNQEIKPKKLTLGNSKLLLNKSFDSLTGAQSFVNAKSKTLVEVRKSSIGSTTTISLNKERNSLDQSVIDSNKEEFNRRLSILKKAAEQSKLHDPAQISTLSKLASINQSINSKNEQSITDKAVEQKHQNIEDNKVEIAAKIVQDNENISSQIPKKKKETLAKSVLVGMRTRYGIEEEPALEKTVDNKVVVPKIKLEESKKFKKADLFNMLSDDENGSGRTRSLASIKRAREKEKRKLVSQVPEKVYREVTIPEVIGVGDLANAMSERVADVIKELMKLGILANASQTIDADTAELVATNLGHTVTRVQESDVENILINDDKVEDLRTRAPVVTVMGHVDHGKTSLLDALKSTDIAAGELGGITQHIGAYRVTLADSKAITFIDTPGHEAFSEMRSRGAKVTDIVIIVVAADDGIKTQTVEAINHAKAAGVPIIVAINKIDKPDIDIERIKNELYVHEIIGEEAGGDVIFIPISALKKINLDKLEEAILLISEMQDLKASPFGLASGVVIESKIEKGRGTLTTILVQRGTLRNGDIIIAGTSYGKVKKMINDKGREILEATPSVPVEIQGLNEVPFAGDQFNVVQNEKQAKDIAEYRIRLAKEKKISVASRSSLEELLLKASGNSKIKELPLIIKCDVQGSIEAISGSLLKLPSDEIKLRILHSGVGPITESDVSLAHVSSAIVVGFNVRAWANALTAAEKTKVDIRYYSIIYNLIDDVKAIMSGMLEPIVREQYIGSVEIRQIFNITKIGKIAGSYVTKGIIKKGAGVRLLRDNVVIHAGKLKTLKRFKDEVKEVREGYECGIAFENYEDIREGDTVEVFELVQEQRQL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP4_ROTHL
Sequence: MASLIYRQLLTNSYSVDLHDEIEQIGSEKTQNVTINPGPFAQTRYAPVNWRHGEINDSTTVEPVLDGPYQPTTFKPPNDYWLLISSNTDGVVYESTNNSDFWTAVIAVEPRVSQTNRQYILFGENKQFNIENNSDKWKFFEMFKGSSQSNFSNRRTLTSNNRLVGMLKYGGRVWTFHGETPRATTDSSNTADLNNISIVIHSEFYIIPRSQESKCNEYINNGLPPIQNTRNVVPLSLSSRSIQYRRAQVNEDITISKTSLWKEMQYNRDIIIRFKFGNSVIKLGGLGYKWSEISYKAANYQYSYSRDGEQVTAHTTCSVNGVNNFSYNGGSLPTDFSISRYEVIKENSYVYIDYWDDSKAFRNMVYVRSLAANLNSVKCAGGSYNFRLPVGEWPIMNGGAVSLHFAGVTLSTQFTNFVSLNSLRFRFSLTVDEPSFSIIRTRTVNLYGLPAANPNNGNEYYEMSGRFSLISLVPTNDDYQTPIMNSVTVRQDLERQLSDLREEFNSLSQEIAMSQLIDLALLPLDMFSMFSGIKSTIDLTKSMATSVMKKFRKSKLATSISEMTNSLSDAASSASRSASVRSNLSVISNWTDASKSTSNITDLVNDVSTQTSTISKKLRLKEMITQTEGMSFDDISAAVLKTKIDMSTQIGKNTLPDIVTEASEKFIPKRSYRVLKDNEVMEINTEGKFFAYKVDTLNEIPFDINKFAELVTDSPVISAIIDFKTLKNLNDNYGITRMEALNLIKSNPNVLRNFINQNNPIIRNRIEQLILQCKL
What is the function of this protein?
Forms the head of the spikes and mediates the recognition of specific host cell surface glycans.  It is the viral hemagglutinin and an important target of neutralizing antibodies.  In sialic acid-dependent strains, VP8* binds to host cell sialic acid, most probably a ganglioside, providing the initial contact.  In some other strains, VP8* mediates the attachment to histo-blood group antigens (HBGAs) for viral entry.
What are the official names of this protein?
Outer capsid protein VP4, Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP4 family.
What are the subcellular locations of this protein?
[Outer capsid protein VP4]: Virion. Host rough endoplasmic reticulum. Host cell membrane. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum-Golgi intermediate compartment. Note=The outer layer contains 180 copies of VP4, grouped as 60 dimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple- layered particles. VP4 also seems to associate with lipid rafts of the host cell membrane probably for the exit of the virus from the infected cell by an alternate pathway. SUBCELLULAR LOCATION: [Outer capsid protein VP8*]: Virion. Note=Outer capsid protein. SUBCELLULAR LOCATION: [Outer capsid protein VP5*]: Virion. Note=Outer capsid protein.
Protein: MIAA_YERPS
Sequence: MNDIENLDRPPAIFIMGPTASGKTALSIALRQRLPVELVSVDSALIYRGMDIGTAKPSAQELALAPHRLIDIRDPAESYSAADFRKDALKEMADITAAGRIPLLVGGTMLYFKALLDGLSPLPSADPQVRQRIEQQASELGWGALHQQLAVIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTKISGETLPYRVHQFAIAPASRELLHQRIELRFHQMLDAGFEAEARVLFDRGDLHTDLPAIRCVGYRQMWSYLSGEIDYNDMVYRGVCATRQLAKRQMTWLRGWSSVQWLDSDKPGEALDSVIQVVSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: LEUD_PSYA2
Sequence: MQAYNTQKGIVCPLDRANVDTDQIIAKQFLKSIKRTGFGVNLFDDWRYLDEGYPGQDNSTRIINPDFILNKPRYQGASILLARRNFGCGSSREHAPWALSEYGFRTVIAPSFADIFYNNCFKNGMLPIVLDEEIVDSLMKATFANEGYELTADLERQVVITPTGEEYAFEVDDFRKHCLLNGLDDIGLTLQQSDAIKDYEQKMMQKTPWIFNEVRA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RSE1_CRYNB
Sequence: MHLLNLTLSSPTNVSTAVVGSFSGSKSQEILCVRGGTKLEIFKLNATTGQLDTIVSTEAFGTIRNIAGFRLAGMTKDYILATSDSGRLSILEFVISPTPHFESLYQEVFGKSGSRRIVPGQFLAVDPKGRSCLVGSLEKTKLVYVLNRNTEGKLYPSSPLEAHKNHTLVTHIVGVDQGYDNPLYAALETDYSESDQDSTGEAYENTQKHLTFYELDLGLNHVVRKWSEPTDRRANLLVQVPGGQNANSDRFEGPSGVLVCTEDHIIWKHMDVEAHRIPIPRRRNPLVQRGDKSRGLIIVSAVMHKIKGAFFFLLQSEDGDLYKVWIEHNGEDVVALKIKYFDTVPVANSLCILKRGYIYVASEFSDQNLYQFQSLAEDDGEQEWSSTDYPENGNIDGPLPFAFFDPQPLRNLLLVDTVPSLDPITDAHVVNLLGASSDTPQIYAACGRGARSTFRTLKHGLDVAEMVSSPLPGVPTNVWTLKLTEDDEYDSYIVLSFPNGTLVLSIGETIEEVNDTGFLSSGPTLAVQQLGNAGLLQVHPYGLRHIRAADRVDEWPAPPGQTIVAATTNRRQVVIALSTAELVYFELDPEGSLSEYQEKKALPGNATCVTIAEVPEGRRRTSFLAVGCDNQTVSIISLEPDSTLDTLSLQALTAPPTSICLAEIFDTSIDKNRATMFLNIGLMNGVLLRTVVDPVDGSLSDTRLRFLGAKPPKLVRANVQGQPSVMAFSSRTWLLYTYQDMLQTQPLIYDTLEYAWSLSAAMCPDGLIGISGNTLRIFNIPKLGEKLKQDSTALTYTPRKFISHPFNSVFYMIEADHRTYSKSAIERIVKQKESEGRRVDTLLLDLPANEFGRPRAPAGHWASCVRVLDPLANETIMTLDLDEDEAAFSIAIAYFERGGGEPFLVVGTGVKTTLQPKGCKEGYLRVYAIKEQGRILEFLHKTKTDDIPLCLAGFQGFLLAGIGKSLRLYEMGKKALLRKCENNGFPTAVVTINVQGARIIVGDMQESTFYCVYRSIPTRQLLIFADDSQPRWITCVTSVDYETVACGDKFGNIFINRLDPSISEKVDDDPTGATILHEKSFLMGAAHKTEMIGHYNIGSVVTSITKIPLVAGGRDVLVYTTISGAVGALVPFVSSDDIEFMSTLEMHMRTQDISLVGRDHIAYRGYYVPIKGVVDGDLCESFSLLPYPKQQAIALDLDRSVGDVLKKLEQMRTSSAF
What is the function of this protein?
Involved in pre-mRNA splicing and cell cycle control.
What are the official names of this protein?
Pre-mRNA-splicing factor RSE1.
What is the protein family that this protein belongs to?
Belongs to the RSE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RBFA_AGRFC
Sequence: MAKATSSAPSQRMLRVGEQVRAALTQILQRGEVRDDLIEGTVISISEVRMSPDLKIATAYVTPLGVADHTDIISALNRHAKFMRGRLGPQLRQMKYMPELRFRDDTSFDNYQKIDALLRSPEVQRDLGPSNEKDDEQN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SNAZ2_LYCMC
Sequence: MQLKIQLLMLVLMTVLTGVLGKDGYVVHEDTNCKYSCDVFKKWKYCSPLCQKKGAETGYCYSFACWCVGLPEETLVYGDKGTYCWE
What is the function of this protein?
Binds voltage-independently at site-3 of voltage-gated sodium channels (Nav) and inhibits the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Neurotoxin LmNaTx35.2.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACDA1_METTE
Sequence: MSKLTTGSFSIEDLESVQITINNVIGAAKEAADEKAKDLGPMGPSAWPGLATYRDDWNLKLLDRYEPVITPMCDQCCYCTYGPCDLSNNKRGACGIDMLGHNGREFFLRVITGTACHAAHGRHLLDHLIEVFGEDLPLKLGQSDVLTPNITITTGQRPMTLGEIKPAMEHTEEQLTQLLATVHAGQESAEIDYDSKALFSGSLDHVGMEISDIVQIAALDFPKADPEAPLIEMGVGTIDKEKPFLCVIGHNVGGVTYMMDYMEEHDLTGKMELGGLCCTAIDLTRYKEADRRAPYTKVIGSMSQELKIIRSGLPDVIVVDEQCVRGDIVPEAQKLGIPVIASNAKIMYGLPNRDEQDVDATIEELKSGAIPGAVILDYDKLGEISVRLTQEMHPLREAAGLRKIASDEQMKEWVDKCADCGSCYLVCPEELEIPEAMKHAKEGDYSYLVDLHDQCIGCRRCEQVCKKEIPILSVIEKASQKVIAEEKGWMRAGRGQVSDAEIRAEGLNLVMGTTPGIIAIIGCPNYGDGAKSVYYIAEEFLKRNFIVVGTGCGAMDMGMYKDENGQTLYERFPGGFQSGGLVNIGSCVSNAHITGAAQKVAGIFGGRTMEGNLAEIADYVLNRVGACGLAWGAFSQKASSIGTGCNIYGIPAVLGPHSSKYRRALISKNYDDEKWKVYDARSGEEMAIPPAPEFLLITAETWQEAIPMMAKACIRPSDNSMGRSIKLTHWMELHQKYIGGMPEDWWKFIRTEADLPLAKRAELMKKLEEEHGWEIDWKRKKIISGPKIKFDVSAQPTNLKRLCKGA
What is the function of this protein?
Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit alpha 1, ACDS complex subunit alpha 1, ACDS complex carbon monoxide dehydrogenase subunit alpha 1, ACDS CODH subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the Ni-containing carbon monoxide dehydrogenase family.
Protein: TRMD_CLOP1
Sequence: MKINILTLFPEMFDIFKHSIIGRARENGFLHIETVNIRDYTLNKHKKVDDYPYGGGAGMVMTPQPVVDAIKAVKEKNKGKVIFLGPRGKTFNQEMAKELSKEEELIFVCGHYEGIDQRVYKYFDLEISLGDFVLTGGEMACIPVIDSISRLVPGVLGSEESFQDESYYDGTLEYPQYTRPFEFEGEKVPEVLMSGHHENIRKWRRKQSLLITKERRPDMFEKIKLSKEDIKLLKSK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_PEDPA
Sequence: MEKNTIILAAGQGTRMKSKLYKVLHQVCGKAMVDHMLTQVEKTNMDHIVTIVGHGAEKVRELLGDRTEYAIQEQQLGTGHAVLQAEKILGDKDGMTMIVSGDTPLFTAKTFENLFEYHRQKGAAATILTARTENPFSYGRIVRNEVGVVSKIVEQKDATTEEAEIKEINTGVYCFDNQKLFAALHQVKNDNAQGEYYLPDVIGIMKDAGEIVAAYEMADFSESMGVNDRLALSKATKVMQRRINEEHMVNGVTIIDPENTYIDYGVEIGPDTIIEPGVQIQGNTKIGSSSVIGAHSKIVDSTIGNRVTVTSSQIESAIMHDDSNIGPHSHLRPQAEIGEFAHVGNYCEVKNAKLGARTKMGHLSYVGDADLGTDINIGCGVVFVNYDGMNKHHSTVGDYAFIGSNSNIVAPVTIADHSYVAAGSTITNDVNKFEMGIARGRQVNKEGYFKKLPVYDAALKAEEENNK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.