PharMolix/UniProtQA huggingface dataset:
Protein: S4A7_RAT
Sequence: MEADGAGEQMRPLLTRGPDEEAVVDLGKTSSTVNTKFEKEELESHRAVYVGVHVPFSKESRRRHRHRGHKHHHRRRKDKDSDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDDSIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLSHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSLSRLTSRSSQQTQPQAPEVLVSPDRDDIPRVVIHPPEEDIEALKGQEQKNEENTDFTPGILASPQSAPGNLDSSKSGEVKGNGSGGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLSGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPAFPNGSAPVSADPPKEADHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILFKFCRDYHLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFHLGEIYAFNMHNNLDALTSYTCVCAEPSNPSNETVELWERKNVTAASISWANLTVSECKTFHGMFVGSACGPHGPYVPDVLFWCVVLFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVAIDYLVGIPSPKLHVPEKFEPTDPSRGWIISPLGDNPWWTLLIAAVPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQFFDRIKLFGMPAKHQPDLIYLRYVPLWKVHVFTVVQLTCLVLLWVIKASAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQGDGDTVHLPFERGSLLQIPVKTLKYSPEKPVSVTINFEDEPSKKYMDAETSL
What is the function of this protein?
Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry (PubMed:10850716, PubMed:15075186, PubMed:14673192).  Mediates the sodium-dependent bicarbonate transport important for pH recovery after acid load as well as for regulation of steady-state pH in the duodenum and vascular smooth muscle cells (By similarity).  Plays a key role in macrophage acidification, mediating bicarbonate import into the cytoplasm which is crucial for net acid extrusion and maintenance of cytoplasmic pH during phagocytosis (By similarity).  Provides cellular bicarbonate for de novo purine and pyrimidine synthesis and is a key mediator of de novo nucleotide synthesis downstream of mTORC1 signaling in proliferating cells (By similarity).
What are the official names of this protein?
Sodium bicarbonate cotransporter 3, Electroneutral sodium bicarbonate cotransporter 1, NBC-like protein, Solute carrier family 4 member 7.
What is the protein family that this protein belongs to?
Belongs to the anion exchanger (TC 2.A.31) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, stereocilium. Note=Also described at the apical cell membrane. Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells.
Protein: IOVO_LEIOC
Sequence: VVTVDCSGYPTHACTLELKPLCGSDNQTYSNKCGFCNAVAQSNGTLTLSHFGKC
What are the official names of this protein?
Ovomucoid.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_SHELP
Sequence: MKFVDEAVIRVEAGDGGSGCVSFRREKYVPDGGPDGGDGGDGGSVYLQADENLNTLIDYRFERFHFAERGENGRGRDCTGHGGKDLILKVPVGTRAVDEETQEALGDLKTHGQKLLVAKGGFHGLGNTRFKSSTNRAPRQKTLGTPGEVRSLRLELMLLADVGLLGMPNAGKSTFIRSVSRAKPKVADYPFTTLVPNLGVVTPRHGQSFVIADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHILDIEPIDGSDPVDSARAIVGELEKHSPLLASKPRWLVFNKTDLLLEEELQERVDRIVKELDWQGDVYCISAYNREGTQELALKLMDFIDALPPEVEEDPDAEVEFKWDNYHQKTQEVVNEDYDDDFDDDFDDDDYDVEIIYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_DESOH
Sequence: MPLIPMVIEQTSRGERAFDIYSRLLKDRIVFIGSAIDDETANLLIAQLLFLESEDPDKDINFYINSPGGKVSAGMAIYDTMQYIKSDIATVCIGHAASMGAFLLAAGAKGKRFSLPNSRIMIHQPMGGAQGQASDIAIQAKEILRMKDILNQILAHHTGKPLEQIQVDTDRDFFMSGEEAKAYGIVDHVITDRSDLDKLEKPQEA
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDR1_YEAST
Sequence: MRGLTPKNGVHIETGPDTESSADSSNFSTGFSGKIRKPRSKVSKACDNCRKRKIKCNGKFPCASCEIYSCECTFSTRQGGARIKNLHKTSLEGTTVQVKEETDSSSTSFSNPQRCTDGPCAVEQPTKFFENFKLGGRSSGDNSGSDGKNDDDVNRNGFYEDDSESQATLTSLQTTLKNLKEMAHLGTHVTSAIESIELQISDLLKRWEPKVRTKELATTKFYPNKSIETQLMKNKYCDVVHLTRYAAWSNNKKDQDTSSQPLIDEIFGLYSPFQFLSLQGIGKCFQNYRSKSKCEIFPRTAKETIYIMLRFFDVCFHHINQGCVSIANPLENYLQKMNLLPSTPSSISSAGSPNTAHTKSHVALVINHLPQPFVRNITGISNSELLSEMNNDISMFGILLKMLDMHKNSYQNFLMEITSNPSVAKNTQSIDVLQEFIHYCQAGEALIALCYSYYNSTLYNYVDFTCDITHLEQLLYFLDLLFWLSEIYGFEKVLNVAVHFVSRVGLSRWEFYVGLDENFAERRRNLWWKAFYFEKTLASKLGYPSNIDDSKINCLLPKNFRDVGFLDNRDFIENVHLVRRSEAFDNMCISDLKYYGELAVLQIVSHFSSSVLFNEKFTSIRNTSKPSVVREKLLFEVLEIFNETEMKYDAIKEQTGKLFDIAFSKDSTELKVSREDKIMASKFVLFYEHHFCRMVNESDNIVARLCVHRRPSILIENLKIYLHKIYKSWTDMNKILLDFDNDYSVYRSFAHYSISCIILVSQAFSVAEFIKVNDVVNMIRVFKRFLDIKIFSENETNEHVFNSQSFKDYTRAFSFLTIVTRIMLLAYGESSSTNLDVISKYIDENAPDLKGIIELVLDTNSCAYRFLLEPVQKSGFHLTVSQMLKNRKFQEPLMSNEDNKQMKHNSGKNLNPDLPSLKTGTSCLLNGIESPQLPFNGRSAPSPVRNNSLPEFAQLPSFRSLSVSDMINPDYAQPTNGQNNTQVQSNKPINAQQQIPTSVQVPFMNTNEINNNNNNNNNNKNNINNINNNNSNNFSATSFNLGTLDEFVNNGDLEDLYSILWSDVYPDS
What is the function of this protein?
Positive regulator of proteins involved in permeability.  PDR1 and PDR3 jointly control the transcription level of both SNQ2 and PDR5.
What are the official names of this protein?
Transcription factor PDR1, Pleiotropic drug resistance protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYC_LACE2
Sequence: MRIYNTLSRRKEEFKPLEEGKVKMYVCGPTVYNLIHIGNARPMIVFDTVRRYLEYKGYDVNYVSNFTDVDDKIIKKANEEGVSAEEISTRYIAECKKDMEGMNIKPATTHPLATQEIGGMIDMIQTLIDKGYAYEVNGTVYYRTRKFAEYGKLSKKNIDDLEAGHRDEAHSLKVTGEDEKEDPLDFVLWKPKKEGEPSWPSPWSDGRPGWHIECSVMSKKYLADEIDIHAGGEDLIFPHHENEIAQSEAANGVPFSKYWMHNAFLNIDNKKMSKSLGNFFTVRDISREYDLEVLRFFMLSAHYRNPVNFSHDLMESAKNGLDRILTAVDNLRHLSENAKDVIMTEDEKKIIASIDDIYKKFEDSMDDDFNTADAISAIFELVKLANSNSSSDNSKEYIDTLMKKITTLTDILGLKTDKKEEMLDEDIEALIAERQQARKDKNFARADEIRDELLAKGIVLKDTREGVRWSRA
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_HELPG
Sequence: MTKIAMANFKSAMPVFKSHAYLKELEKTLKPQHFDRVFVFPDFLGLLPNSFLHFTLGAQNAYPRDCGAFTGEITSKHLEELKIHTLLIGHSERRALLKESPSFLKEKFGFFKDKNFKIVYCIGEELTTREKGFRAVKEFLNEQLENIDLNYSNLIVAYEPIWAIGTKKSASLEDIYLTHGFLKQILNQKTPLLYGGSVNVQNAKEILGIDSVDGLLIGSASWELENFKTIISFL
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPRT_METPS
Sequence: MLKNLRETMRTAPIVRRGTYNYFIHPISDGVPVVKPELLREVIACMVKNADLDVDKIVTIEAMGLPLGAALSTMTDIPFIIIRKRKYELPGEIAVHQTTGYSRGELYLNGINKGDRVLIIDDVISTGGTMKAVIKALEKAGAVIKDIVVVIERGDGKKSIEELGYDVQTLIKIDVDENGVKILGCIDEECQ
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis.
What are the official names of this protein?
Hypoxanthine/guanine phosphoribosyltransferase, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSH_THEVO
Sequence: MTNVPDGLKYTKTHEWYKVDNGIATVGITDYAQSQMTDIVYVDLPEVGDKKKVGDVLLTIESVKSAEDVYSPLTGEITEVNQELTKHPENINKDPYGNWLVKMKVEKEGEYLTAEQYRKLIQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Probable glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CGR1_COCIM
Sequence: MSSTEPAPAPAPEPAPAPAAAPAAAAAAPKGMRKNGKNWHDVKTPFRPTKGQTSYARRLEERKAMAAIKEKEKEMKEEKEAERQRRIQAIKDRRAAKEEKERYEKMAEKMHRKRVERRKRREKRNKLLNS
What is the function of this protein?
Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
What are the official names of this protein?
rRNA-processing protein CGR1.
What is the protein family that this protein belongs to?
Belongs to the CGR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CG031_MOUSE
Sequence: MEVIHGRPHCCRNLEGADILSNTFYSNGLHTPYETTIRPTASQARYQELREALPQCRLRWGADREYGGVLPVSLPEEHRPKCEPPRLMSKGHQHYGFGGEIWPKKLPIEQYYYMTQNKKSDVYGNDSLLPKPPNSAVKEICSPYPIEHPYHTHISRGSVFPTFTSPKDLYTGIKARTQQPFPPTVPTKACDTTILKTRGNPYRYELLDFPMDSKKKALTWPGQGVYYDFPKFVEKNKPVFYPKPPKTFAPNSSVNPWDTMSSAKDANIQRNLERSHWLTSYAHDFTGLGPMSPLELDDYHEKELAELTGQIGFDPQPQEKFHPALKTPRPLDGRIARLTQNQRPLEATVQIPPPCPDCTPRVLCAFHTFIPTSAEIMAMNNNLLSGITHKNQDVEEKIKEEQGLMSTCPLPTCYESKDLTSLYDVQSFPKITDTKKTDDLYWRQLEMKPLPISCSKSNHYIDYEPLKSAYRDPYAMCPNPVRLSKSNILQNKTDTADFTFDNFLSKPEFLGMNMESNEETRPLLDWIPRAGVPKHHSNLRNLRNTFSKSMAQKRLHNSIQEEQKDLRDKLQCGMRHQFFGYNGHHFYN
What are the official names of this protein?
Uncharacterized protein C7orf31 homolog, Protein TISP74.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: LIPB_EHRRW
Sequence: MEWKIESLPVPYDKAMCFMQQRVEGIANKTQDELVWLLEHFPLYTAGTSARSEELLTDSLFPVYSTGRGGKYTYHGPGQRIAYVMMDLKARDKCNVRLYVETLGEWIVKTLKHFSIRSYFNPNLIGVWVNHNGSEKKIAAFGIRIRKWITYHGVSINVFTDLSHYSGIIPCGIKEYGITSLKTLGVNILYEEFDVVLKKEFNKVFCNC
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GNA13_RAT
Sequence: MADFLPSRSVLSVCFPGCVLTNGEAEQQRKSKEIDKCLSREKTYVKRLVKILLLGAGESGKSTFLKQMRIIHGQDFDQRAREEFRPTIYSNVIKGMRVLVDAREKLHIPWGDNKNQVHGDKLMAFDTRAPMAAQGMVETRVFLQYLPAIRALWDDSGIQNAYDRRREFQLGESVKYFLDNLDKLGVPDYIPSQQDILLARRPTKGIHEYDFEIKNVPFKMVDVGGQRSERKRWFECFDSVTSILFLVSSSEFDQVLMEDRLTNRLTESLNIFETIVNNRVFSNVSIILFLNKTDLLEEKVQVVSIKDYFLEFEGDPHCLRDVQKFLVECFRGKRRDQQQRPLYHHFTTAINTENIRLVFRDVKDTILHDNLKQLMLQ
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:12176367).  Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (By similarity).  GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (By similarity).  Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (By similarity).  Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (By similarity).
What are the official names of this protein?
Guanine nucleotide-binding protein subunit alpha-13, G alpha-13, G-protein subunit alpha-13.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(12) subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Melanosome. Cytoplasm. Nucleus. Note=Cytoplasmic in adult somatic cells, but mainly nuclear in spermatids in the testes. Translocates from the cytoplasm to the nucleus during spermatogenesis, hence predominantly observed in the cytoplasm of round spermatids but localized in the nuclei of elongating or elongated spermatids and testicular spermatozoa.
Protein: KDKA_XANOP
Sequence: MVSFDATEALAPYREGRGYGAIVFDRERLRQADASLFSPQSWGDRARPVDKGGRGGAWFVDAPFGRSVLRQYLRGGMAARVSRDRYLWKGAGRTRSFAEFRLMRELIKRKLPVPRPLAACYLREGLGYRAALLMERLENVRSLADHAQLAGRGAPWEATGQLIARFHRAGLDHPDLNAHNILFDAGGHGWLIDFDRGVLRIPATRWRERNLKRLHRSLLKLRGNRSGEDVDKDYERLHRAYELAWGRGY
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid kinase, Kdo kinase.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. KdkA/RfaP family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CBIM_CARHZ
Sequence: MVEGMLKTNFRLLFLLIFLLIPTPVLAMHIMEGFLPVKWVIFWDLVTLPFIMVGFIRLQREATQGPGAKLMLAFAGAFIFVLSALKMPSVTGSCSHPTGTGLAAILFGPFITTVLGFIVLIFQALLLAHGGLTTLGANTFSMAVAGPLVAYGVYKGLQKAGINSNFSIFLAAMLGDLVTYIVTSVQLALAFPGSSLFLSALKFMGIFALTQIPLAISEGILTVLTYNFLSRYEDAKIWVEKGEH
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiM, Energy-coupling factor transporter probable substrate-capture protein CbiM, ECF transporter S component CbiM.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: 3BHS1_HUMAN
Sequence: MTGWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKETLKSKTQ
What is the function of this protein?
A bifunctional enzyme responsible for the oxidation and isomerization of 3beta-hydroxy-Delta(5)-steroid precursors to 3-oxo-Delta(4)-steroids, an essential step in steroid hormone biosynthesis.  Specifically catalyzes the conversion of pregnenolone to progesterone, 17alpha-hydroxypregnenolone to 17alpha-hydroxyprogesterone, dehydroepiandrosterone (DHEA) to 4-androstenedione, and androstenediol to testosterone.  Additionally, catalyzes the interconversion between 3beta-hydroxy and 3-oxo-5alpha-androstane steroids controlling the bioavalability of the active forms.  Specifically converts dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR.  Also converts androstanedione, a precursor of testosterone and estrone, to epiandrosterone (PubMed:1401999, PubMed:2139411).  Expected to use NAD(+) as preferred electron donor for the 3beta-hydroxy-steroid dehydrogenase activity and NADPH for the 3-ketosteroid reductase activity (Probable).
What are the official names of this protein?
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I, 3-beta-HSD I, 3-beta-hydroxy-5-ene steroid dehydrogenase, 3-beta-hydroxy-Delta(5)-steroid dehydrogenase, 3-beta-hydroxysteroid 3-dehydrogenase, Delta-5-3-ketosteroid isomerase, Dihydrotestosterone oxidoreductase, Steroid Delta-isomerase, Trophoblast antigen FDO161G.
What is the protein family that this protein belongs to?
Belongs to the 3-beta-HSD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein.
Protein: MUTL_PSEPK
Sequence: MSGGSRIQLLSPRLANQIAAGEVVERPASVAKELLENSLDSGARRIDIEVEQGGVKLLKVRDDGSGISADDLPLALARHATSKIRELEDLEGVLSLGFRGEALASISSVARLTLTSRTASASEAWQVETEGRDMTPRVQPAAHPVGTSVEVRDLFFNTPARRKFLKAEKTEFDHLQEVIRRLALARFDVGFHLRHNGKSILSLHEAHDEIARARRVGAICGPGFMEQALPIDVERNGLRLWGWVGLPTFSRSQADLQYFFVNGRAVRDKLVAHAVRQAYRDVLFNGRHPTFVLFLELEPNGVDVNVHPTKHEVRFREGRSVHDFLYGTLHRALADVRPEDQLAAPAAVPELVRPTGQQAGEFGPQGEMRLASPVLEQPRAPQQSFSNGGSGAGYQYQYTPRPSQPLPAAEAQAVYREFYKPLETGAAPATALPESQGDIPPLGYALAQLKGIYILAENAVGLVLVDMHAAHERIMYERLKVAMASEGLSGQPLLVPETLALSQREADCAEEHAQWFQRLGFELQRLGPETLAIRQIPALLKQAEANRLVQDVLADLMEYGTSDRIQAHLNELLGTMACHGAVRANRRLAIPEMNALLRDMENTERSGQCNHGRPTWTQMGLDDLDKLFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MRAZ_AZOVD
Sequence: MFRGANAVSLDAKGRISMPARYREELMARSAGQLIVTIDAMDPCLCIYPLPEWELIETKLRELPSLREETRRLQRLLIGNAVDLELDGSGRFLIPPRLREHASLDKHAMLVGQLNKFQLWNEDAWIAIANADLAAIKQQPGDLPGELRDLIL
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HIS8_METBF
Sequence: MFLSRPELIKKEIFDIAEYVPGKSIEEIASAYGLDPASIIKLGSNENPLGPSPKAVQAMMDTAPFANIYPSADAIELREALSRYTGFPVSNLIASGPGMDGLLDGLCRLVIEKGDEVIVPTPTFAYYELPARACGGKPVFVRRSQDFSIDPEKLLEATSSRTKIIFLCSPNNPSGNLLPEKDLRKVLENTRALVFVDEAYVEFADRNLAELVREYDNLVVGRTFSKVFGLAGLRLGYGIMPEWLAKEYIRAATPFSVSLPALKAGIAALSDVEHRKKSIEIAREGRKYLKEKIPFKVYPSQANFVLVDVSPLKAKAVTQSLMKKGIIVRSCDSFRDAGDTLIRATAGTLEQNEKVVRAFETAKKEV
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL11_ECO5E
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RR7_PORPU
Sequence: MSRRNTAKKRFASPDPLYKSRLVSMLTVRILKSGKKTLAQRIIYQALDIVKERTETDPLNVLEKAIRNITPLVEVKARRVGGSTYQVPIEVRAYRGTNLALRWITRFSRERSGKSMSMKLANEIMDAANETGNSIRKREETHRMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PAGP_EDWTE
Sequence: MKTHNDILAALAALPLFLTGAAFAAEPGMLDTLRNNIVQTWEQPQHYDLYLPAITWHARFAYSQEKIDSYNERPWGAGFGQSRWDEKGNWHGLYLMAFKDSFNKWEPIGGYGWEATWRPLEGSDFHWGAGYTVGVTMRDNWRYIPIPVILPMASVGYGPLTLQMTYIPGTYDNGNVYFAWLRLQF
What is the function of this protein?
Transfers a fatty acid residue from the sn-1 position of a phospholipid to the N-linked hydroxyfatty acid chain on the proximal unit of lipid A or its precursors.
What are the official names of this protein?
Lipid A acyltransferase PagP, Lipid A acylation protein.
What is the protein family that this protein belongs to?
Belongs to the lipid A palmitoyltransferase family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: UPPP_MICLC
Sequence: MTWIEAIILGLVQGLTEFLPISSSAHIRIVGEFLPSATDPGAAFTAITQLGTELAVLIYFWRDITRIIGRWSAAVTGRIPHSDPDARMGWLIIVGSIPIAVLGLLLEDWIDTEFRSLWITATMLIVFGVLLALADRLGRQTKPLEKLTVRDGVLYGLAQALALIPGVSRSGGTIAAGLAMGYTRPAATRYAFLLAVPAVFASGLYKLYTSLTDPGTQGPYGMGETLVATAVAFVVAYAVIAWLMRFISTNSYLPFVWYRILLGGVLFALLGAGVISA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURC_STAA8
Sequence: MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVILFMGAGDIQKLQNAYLDKLGMKNAF
What is the function of this protein?
Cell wall formation (PubMed:20659527).  Can also use L-serine and glycine, but they are incorporated 4. 3- and 7-fold less rapidly, respectively, than L-alanine (PubMed:20659527).
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_ALBFT
Sequence: MATIGRRAYAEMFGPTVGDRVRLADTNLIIEVEDDYTLRAGGYGEEVKFGGGKTIRDGMAQSQRSRAEGAVDTVMTNALIIDHWGIVKADIGLKDSRIVAIGKAGNPDTQPGVDIIIGPGTEVISCEGSIVTAGGFDSHIHFICPQLIEEALSSGITTMTGGGTGPATGTFATTCTPGSWHIERMLQAADAFAMNLGFMGKGNASLPAALHEQINAGALGLKLHEDWGTTPAAIDNCLNVAELTDTQVAIHTDTLNESGFVEDTLAAFKGRSIHTFHTEGAGGGHAPDIMKLVGEPNVLPSSTNPTRPYTVNTLDEHVDMLMVCHHLDAAIAEDLAFAESRIRKETIAAEDILHDLGAISIMSSDSQAMGRVGEVIIRTWQTAHKMKAQRGWLAPPPERSEPVEKLQRNDNYRVKRYLAKYTINPALTHGMAHEVGSIELGKWADLVVWRPAFFGVKPSLIVKGGSIAMAAMGDPNASIPTPQPVHYRPMFGAFGGALARGSLTFVSQAGLNAGIGARYGLSKTLSAVKNIRGIRKEHMVHNHYLPKMEIDAQTYSVRADGELLTCEPAVSLPMTQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_PSE14
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEHATAVVRYQGGHNAGHTLVIDGEKTVLHLIPSGVLREGVQCLIGNGVVVAPDALLREIIKLEEKGIPVRERLRISPSCPLILSYHVALDQAREKARGEFKIGTTGRGIGPAYEDKVARRGLRIGDLFHRERFAAKLGELLDYHNFVLVNYYKEPAIDFQKTLDECMEYADLLKPLMLDVTAALHEMRRDGKDIMFEGAQGSLLDIDHGTYPYVTSSNTTAGGIATGSGFGPMYLDYILGITKAYTTRVGSGPFPTELFDDVGAFLAKRGHEFGATTGRARRCGWFDAVILRRAIEINSISGLCLTKLDVLDGLETINICVGYENEEGAVIDAPTDADSYLGLRPVYEQMPGWSESTLGAKTLEELPAAARAYIKRVEELVGAPIDIISTGPDRNETIVLRHPFG
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.