PharMolix/UniProtQA huggingface dataset:
Protein: FPG_BACCZ
Sequence: MPELPEVENVRRTLENLVTGKTIEDVIVTYPKIVKRPDDAEIFKEMLKGETIENIKRRGKFLLLYVTNYVIVSHLRMEGKFLLHQEDEPIDKHTHVRFLFTDGTELHYKDVRKFGTMHLFKKGEEMNQMPLADLGPEPFDAELTPQYLHERLQKTNRKIKVVLLDQRLLVGLGNIYVDEVLFRSQIHPEREASSLTAEEIERIYEATVTTLGEAVKRGGSTIRTYINSQGQIGSFQELLNVYGKKGEPCVTCGTILEKTVVGGRGTHYCPICQPRI
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: AMPA_YERPN
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKVGQTLLLHHVPNILSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNTYWKVRQAVETAKETLYTFDQLKSNKTEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIASGIKAAKDLGNMPPNICNAAYLASQARQLADAFSTNTVTRVIGEQQMKELGMHAYLAVGHGSQNESLMSVIEYKGNPNKDAKPIVLVGKGLTFDSGGISIKPAEGMDEMKYDMCGAATVYGVMRVVAELQLPLNVVGVLAGCENMPGGRAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDALTYVERFEPELVIDIATLTGACVVALGNHLTGLMSNHNPLAHELIGASEQAGDRAWRLPLGEEYYEQLDSNFADMANIGGRAGGAITAGCFLSRFTRKYSWAHLDIAGTAWRSGKNKGATGRPVALLSQFLLNRAGLNGDD
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX21_HUMAN
Sequence: MAAAAVDSAMEVVPALAEEAAPEVAGLSCLVNLPGEVLEYILCCGSLTAADIGRVSSTCRRLRELCQSSGKVWKEQFRVRWPSLMKHYSPTDYVNWLEEYKVRQKAGLEARKIVASFSKRFFSEHVPCNGFSDIENLEGPEIFFEDELVCILNMEGRKALTWKYYAKKILYYLRQQKILNNLKAFLQQPDDYESYLEGAVYIDQYCNPLSDISLKDIQAQIDSIVELVCKTLRGINSRHPSLAFKAGESSMIMEIELQSQVLDAMNYVLYDQLKFKGNRMDYYNALNLYMHQVLIRRTGIPISMSLLYLTIARQLGVPLEPVNFPSHFLLRWCQGAEGATLDIFDYIYIDAFGKGKQLTVKECEYLIGQHVTAALYGVVNVKKVLQRMVGNLLSLGKREGIDQSYQLLRDSLDLYLAMYPDQVQLLLLQARLYFHLGIWPEKSFCLVLKVLDILQHIQTLDPGQHGAVGYLVQHTLEHIERKKEEVGVEVKLRSDEKHRDVCYSIGLIMKHKRYGYNCVIYGWDPTCMMGHEWIRNMNVHSLPHGHHQPFYNVLVEDGSCRYAAQENLEYNVEPQEISHPDVGRYFSEFTGTHYIPNAELEIRYPEDLEFVYETVQNIYSAKKENIDE
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
What are the official names of this protein?
F-box only protein 21.
Protein: TM41_DICDI
Sequence: MEIDNQNINNINNNNIHNNINNNNINKRNIENNINNINNINNNISMKNKNNNIDNKKNSNNNNNNNNNNNNKNSISNNNNNNNKSFGLYSLEQPAPLPLWLLVIVFGVSISVIVFLFLNFPSLSPQHKQLIRLPKNFKDVKLLSDILSQYTDDNYFIVITTFGVIYTFLQAFSIPGSVFLSFLSGGLFGLKVGFPLVCFVATLGATFSYLISYYIGRNLVRKLFPDKLKLFSDSLSQKRDNLLNYIVFLRITPFLPNWFINLASPLLDVPIHTFAIGTFIGIMPATFLAVKAGIQIQNIQNPSDIFDLKSILTMAALALLSILPTLIQKKLKVN
What are the official names of this protein?
Transmembrane protein 41 homolog.
What is the protein family that this protein belongs to?
Belongs to the TMEM41 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PGK_ACIF2
Sequence: MNVLRMMDVPLKGKRVLIREDLNVPMNDAGAITDDTRIRASLPTIRAALASGARVMLMSHLGRPKEGVFDEKASLAPVAAHLSQLLGRDVPLVRDWLDAGKDRLAQLQDGDVVVLENVRFNTGESKDDEALSKKMAALCDVFVMDAFGTAHRAQASTHGVGKFAPVACAGPLLVNELDALGKALQNPRRPLVAIVAGSKVSTKLTILKSLADKVDQLVVGGGIANTFILAAGHSVGKSLCEADLVPDAQAIIAAARAKGGDVPLPSDVVVAKAFSETAPARTCRVDDIAADDMVLDIGPDTAKTLGDILRKAGTIVWNGPVGVFEFDAFAGGTEAIARAVAESSAFSIAGGGDTIAAINKFHIEDKVSYISTGGGAFLEFLEGKTLPAVAMLEERARGTHT
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_CHLCV
Sequence: MTDSSNEHETENPSLPIPDNEIQDLQQEIATLKAELKEKNDKYLMVLAESENARKRMQKERQEMMQYAVENALIDFLVPIESMEKALGFASQMSDEVKNWALGFNMILQQFKQVFEEKGIVEYSSVGQKFNPFLHEAVETEETTKVPEGTIVEEFSKGYKIGERPIRVAKVKVAKAPAPQEKEEVEK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMB_ESCF3
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDILLDPRLRELNMGVLETRNIDSLTEEEENWRRQLVNGTKDGRIPQGESMLELSERMHSALASCLELPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESQWLASGWVVETAGDVSHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: ABP1_YEAST
Sequence: MALEPIDYTTHSREIDAEYLKIVRGSDPDTTWLIISPNAKKEYEPESTGSSFHDFLQLFDETKVQYGLARVSPPGSDVEKIIIIGWCPDSAPLKTRASFAANFAAVANNLFKGYHVQVTARDEDDLDENELLMKISNAAGARYSIQTSSKQQGKASTPPVKKSFTPSKSPAPVSKKEPVKTPSPAPAAKISSRVNDNNDDDDWNEPELKERDFDQAPLKPNQSSYKPIGKIDLQKVIAEEKAKEDPRLVQKPTAAGSKIDPSSDIANLKNESKLKRDSEFNSFLGTTKPPSMTESSLKNDDDKVIKGFRNEKSPAQLWAERKAKQNSGNAETKAEAPKPEVPEDEPEGEPDVKDLKSKFEGLAASEKEEEEMENKFAPPPKKSEPTIISPKPFSKPQEPVKAEEAEQPKTDYKKIGNPLPGMHIEADNEEEPEENDDDWDDDEDEAAQPPLPSRNVASGAPVQKEEPEQEEIAPSLPSRNSIPAPKQEEAPEQAPEEEIEEEAEEAAPQLPSRSSAAPPPPPRRATPEKKPKENPWATAEYDYDAAEDNELTFVENDKIINIEFVDDDWWLGELEKDGSKGLFPSNYVSLGN
What is the function of this protein?
Regulates ARP2/3 complex-mediated actin assembly.  Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches.  Binds to actin filaments, but not actin monomers.  Actin binding is required for ARP2/3 complex activation.  May also have a role in linking the actin cytoskeleton to endocytosis.  recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.
What are the official names of this protein?
Actin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ABP1 family.
Protein: CLC5A_MOUSE
Sequence: MNWHMIISGLIVVVIKVVGMTFFLLYFPQVFGKSNDGFVPTESYGTTSVQNVSQIFGRNDESTMPTRSYGTVCPRNWDFHQGKCFFFSFSESPWKDSMDYCATQGSTLAIVNTPEKLKYLQDIAGIENYFIGLVRQPGEKKWRWINNSVFNGNVTNQDQNFDCVTIGLTKTYDAASCEVSYRWICEMNAK
What is the function of this protein?
Functions as a positive regulator of osteoclastogenesis (PubMed:19251634).  Cell surface receptor that signals via TYROBP (PubMed:10449773).  Regulates inflammatory responses (PubMed:20212065).
What are the official names of this protein?
C-type lectin domain family 5 member A, C-type lectin superfamily member 5, Myeloid DAP12-associating lectin 1, MDL-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: MYG_INIGE
Sequence: MGLSDGEWQLVLNIWGKVEADLAGHGQDVLIRLFKGHPETLEKFDKFKHLKTEAEMKASEDLKKHGNTVLTALGGILKKKGHHEAELKPLAQSHATKHKIPIKYLEFISEAIIHVLHSRHPGDFGADAQAAMNKALELFRKDIAAKYKELGFHG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LGT_TRIV2
Sequence: MALPLAFLFTSPGPVLVEIGPITIRWYGLLIATAVLIGVSLSQYLAKRRQVNPDLLSDLSIWLVIGAIPAARIYYVLFQWSEYAQHPERIIAIWQGGIAIHGAIIGGTLAALIFAKLKRVPFWQLADLVAPSLILGQAIGRWGNFFNSEAFGRPTNLPWKLYIPIERRPPDLASFEYFHPTFLYESIWDLMVFALLITLFFRSLAGKPRLKVGTLFMVYLATYSLGRLWIEGLRTDSLMLGPLRIAQVVSLTGITLGLAGLAWLYVRKRPLPDVVSSPKDTE
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SGF11_ASHGO
Sequence: MTLGRDAMTPLTILSVSETIYHNLLTSMVQDIVSRTTSRQQLQDARYPGLAPLHHDQRGALDVYGRPKPQEASVYFRCPNCSRDLSANRFAAHLERCMSRGARRG
What is the function of this protein?
Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA.  At the promoters, SAGA is required for recruitment of the basal transcription machinery.  It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination.  SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).  SAGA interacts with DNA via upstream activating sequences (UASs).  Involved in transcriptional regulation of a subset of SAGA-regulated genes.  Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
What are the official names of this protein?
SAGA-associated factor 11.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H2B10_ORYSJ
Sequence: MAPKAEKKPAAKKPAEEEPAAEKAEKALAGKKPKAEKRLPAGKAEKSSGEGKKAGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAGESAKLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B.10.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PPIA_HUMAN
Sequence: MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE
What is the function of this protein?
(Microbial infection) Stimulates RNA-binding ability of HCV NS5A in a peptidyl-prolyl cis-trans isomerase activity-dependent manner.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that includes Rho GTPase signaling, actin remodeling, and myosin II activation.
Protein: NTPPA_BACAN
Sequence: MRKIILASGSPRRKELLELAGVPFEIIVSEVEETIGAYSSPSDIVMSLALQKASAVAENNSDHIVLGADTIVTYESRILGKPSNKAEAKEMLQLLSGKTHEVYTGVAIIAKDKTVTFYERTEVTFWELTEEEIDAYVASKEPLDKAGSYGIQGKGSIFVQHIQGDYYSVVGLPISRLVRELKQFNIDVTHA
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDK15_MOUSE
Sequence: MGQELCAKRLQPGCSCYHRSEGGEAHSCQRSQPGSTEPAVFELTEASSSTASFHPRGLEAASAQKLKSKRPRSNSDSFQEENLRQGLPWKKSLPFGAASSYLNLEKLGEGSYAKVYKGISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIVHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQRVLHRDLKPQNLLLSHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPPPKPQSLQIVWDRLGGVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSVLPSQLYQLPDEESLFAVSGVKLKPEMCDLSASYRKRHHLVGVNKCW
What is the function of this protein?
Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.
What are the official names of this protein?
Cyclin-dependent kinase 15, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein homolog, Cell division protein kinase 15, Serine/threonine-protein kinase ALS2CR7, Serine/threonine-protein kinase PFTAIRE-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: PHRA_SYNPZ
Sequence: MKTPLTEAVAAADSQGRFLSNTEVQAASGRFNRAKASLEAAKALTSKADSLVNGAAQAVYSKFPYTTQMEGSNYSATPEGKAKCSRDVGYYLRMITYCLVAGGTGPMDDYLIAGLDEINRTFELSPSWYVEALKHIKANHGLSGDAATEANSYIDYAINALI
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.
What are the official names of this protein?
R-phycocyanin-2 subunit alpha, R-phycocyanin II alpha chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Part of the phycobilisome rod.
Protein: EPMA_SALEP
Sequence: MSETATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGINLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQQPIDQNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA
What is the function of this protein?
With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'.
What are the official names of this protein?
Elongation factor P--(R)-beta-lysine ligase, EF-P--(R)-beta-lysine ligase, EF-P post-translational modification enzyme A, EF-P-lysine lysyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
Protein: CABC1_PROVU
Sequence: MPIFRFTALAMTLGLLSAPYNAMAATSNPAFDPKNLMQSEIYHFAQNNPLADFSSDKNSILTLSDKRSIMGNQSLLWKWKGGSSFTLHKKLIVPTDKEASKAWGRSSTPVFSFWLYNEKPIDGYLTIDFGEKLISTSEAQAGFKVKLDFTGWRAVGVSLNNDLENREMTLNATNTSSDGTQDSIGRSLGAKVDSIRFKAPSNVSQGEIYIDRIMFSVDDARYQWSDYQVKTRLSEPEIQFHNVKPQLPVTPENLAAIDLIRQRLINEFVGGEKETNLALEENISKLKSDFDALNIHTLANGGTQGRHLITDKQIIIYQPENLNSQDKQLFDNYVILGNYTTLMFNISRAYVLEKDPTQKAQLKQMYLLMTKHLLDQGFVKGSALVTTHHWGYSSRWWYISTLLMSDALKEANLQTQVYDSLLWYSREFKSSFDMKVSADSSDLDYFNTLSRQHLALLLLEPDDQKRINLVNTFSHYITGALTQVPPGGKDGLRPDGTAWRHEGNYPGYSFPAFKNASQLIYLLRDTPFSVGESGWNNLKKAMVSAWIYSNPEVGLPLAGRHPFNSPSLKSVAQGYYWLAMSAKSSPDKTLASIYLAISDKTQNESTAIFGETITPASLPQGFYAFNGGAFGIHRWQDKMVTLKAYNTNVWSSEIYNKDNRYGRYQSHGVAQIVSNGSQLSQGYQQEGWDWNRMQGATTIHLPLKDLDSPKPHTLMQRGERGFSGTSSLEGQYGMMAFDLIYPANLERFDPNFTAKKSVLAADNHLIFIGSNINSSDKNKNVETTLFQHAITPTLNTLWINGQKIENMPYQTTLQQGDWLIDSNGNGYLITQAEKVNVSRQHQVSAENKNRQPTEGNFSSAWIDHSTRPKDASYEYMVFLDATPEKMGEMAQKFRENNGLYQVLRKDKDVHIILDKLSNVTGYAFYQPASIEDKWIKKVNKPAIVMTHRQKDTLIVSAVTPDLNMTRQKAATPVTINVTINGKWQSADKNSEVKYQVSGDNTELTFTSYFGIPQEIKLSPLP
What is the function of this protein?
Endolytic, broad-specificity glycosaminoglycan lyase, which degrades the polysaccharides chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, dermatan sulfate and to a lesser extent hyaluronan, by beta-elimination of 1,4-hexosaminidic bond to unsaturated tetrasaccharides and disaccharides.  Is not active against keratan sulfate, heparan sulfate, and heparin.  Is able to promote functional recovery in the injured central nervous system (CNS), via its role in the disruption of the normal organization of the extracellular matrix (ECM).
What are the official names of this protein?
Chondroitin sulfate ABC endolyase, Chondroitin ABC endoeliminase, Chondroitin ABC lyase I, Chondroitin sulfate ABC lyase I, ChS ABC lyase I, Chondroitinase ABC I, cABC I, Endochondroitinase ABC.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 8 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: QUEF_GEOKA
Sequence: MAGRKEEELKDLTLLGNQGTTYSFTYNPNLLEVFDNKHPDRDYFVKFNCPEFTTLCPKTGQPDFATIYISYIPDKKCVESKSLKLYLFSFRNHGDFHEDCVNIIMNDLIKVMEPRYIEVWGKFTPRGGISIDPYCNWGRPGTKYEKMAEYRLLNHDLYPEKVDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1), a late step in the queuosine pathway.  Is highly specific for its natural substrate preQ0, since it cannot use various aliphatic, aromatic and heterocyclic nitriles, although it can reduce the substrate analog 5-cyanopyrrolo[2,3-d]pyrimidin-4-one with lesser efficiency.
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, Nitrile reductase, NRed, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_STAHJ
Sequence: MAKKSVRHIKIREIISSEQIETQDELVKRLNEYDLNVTQATVSRDIKELQLIKVPAPSGQYVYSLPNDRKYHPLEKLGRYLMDSFVNIEGTGNLLVLKTLPGNAQSIGAILDQIDWDEVLGTICGDDTCLLICKDEDASNTIKTRIFNLL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_THET8
Sequence: MAKIGFVSLGCPKALVDSEQILSRLKALGYETSPSYEEAELVIVNTCGFINEAVEESLEVIGEALKENGKVVVTGCLGARPEKIRERHPQVLAITGPGEVERVLEAVQVVLPAPRDPFLDLIPPQVKLTPRHYAYVKLSEGCDHRCSFCIIPKLRGRLRSRDAADVLAEAARLVATGTKELLLVAQDLSAYGVDLGHRESLWGDRPVRAELKDLLAHMAELGAWIRLHYVYPYPHVKDLLPLMAEGKVLPYLDVPLQHASPRILRLMRRPGGYESHLKALKAWREVVPELALRSTFIVGFPGETEEDFQILLDFLEEAELDRVGVFAYSPVEGAEANRLPDPVPEEVKEERKARLLELQARVSLRKNQRFVGKTLEVLVDELPEPGLAVGRTYRDSPGIDGVVYVETDGTVRVGERIPVRILRADTYDLHGVQA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYB1_ARATH
Sequence: MEAEIVRRSEVTGLRREVEESSIGRGDCDGDGGDVGEDAAGFVGTSGRGRRDRVKGPWSKEEDDVLSELVKRLGARNWSFIARSIPGRSGKSCRLRWCNQLNPNLIRNSFTEVEDQAIIAAHAIHGNKWAVIAKLLPGRTDNAIKNHWNSALRRRFIDFEKAKNIGTGSLVVDDSGFDRTTTVASSEETLSSGGGCHVTTPIVSPEGKEATTSMEMSEEQCVEKTNGEGISRQDDKDPPTLFRPVPRLSSFNACNHMEGSPSPHIQDQNQLQSSKQDAAMLRLLEGAYSERFVPQTCGGGCCSNNPDGSFQQESLLGPEFVDYLDSPTFPSSELAAIATEIGSLAWLRSGLESSSVRVMEDAVGRLRPQGSRGHRDHYLVSEQGTNITNVLST
What are the official names of this protein?
Transcription factor MYB1, Myb-related protein 1, AtMYB1.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLE2B_CONCL
Sequence: MNVTVMFLVLLLLTMPLTDGFNIRATNGGELFGPVQRDAGNVLDHGFQRRRECPPRCPTSHCNAGTC
What is the function of this protein?
Increases calcium current amplitude through Cav1. 2/Cav1. 3 channels in rat pancreatic beta-cells, which is a prerequisite for eliciting insulin secretion.  Stimulates insulin secretion in NIT-1 insulinoma cell lines.  In vivo, significantly decreases mice blood glucose levels as of 45 minutes after treatement, similarly to insulin treatment.  Has a potential therapeutic use in endocrinal pathologies such as early stages of type 2 diabetes where the pancreas's capability to produce insulin is still effective.
What are the official names of this protein?
Conotoxin Cl14.2b, Cal14.2b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin L superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRD_POLSJ
Sequence: MSLLPYALARPFLFGLDPETAHELTMASLARTQGTPLSLAWCSSRVNDPIALAGLKFANRVGLAAGLDKNARCIDGLAAMGFGFVEVGTVTPKGQPGNPKPRMFRLPEANALINRLGFNNDGLDAFLANVQQSRVRRQNTPNPLILGLNIGKNAVTPIENAVDDYLTCLDGVYPHADYVTVNISSPNTKNLRALQSDEALDALLGRIAERRESLARQHGKRVPIFVKIAPDLDEAQVDVIAATLKRHAMDGVVATNTTLSRDAVKGLRHAEEAGGLSGAPVLEASNRVIRQLRAALGAGFPIIGVGGVMSGQDAVSKIRAGADVVQIYTGLIYKGPELVNEAALAIKKNR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: HEM1_CHLTB
Sequence: MVREGEERIGNRVLLGVIGVSYRETTLQQREQVLHILQQAQGSFRPEVFQEERDYVLLATCHRVELYSVAPAELFDSLAQEIKLLGVSPYFYRNQDCFAHLFCVAGGLDSLVLGETEIQGQVKRAYLQAAREQKLSFALHFLFQKALKEGKVFRAKGGAPYAAITIPILVDQELRRRQIDKKASLLFIGYSEINRSVAYHLRRQGFSCITFCSRQQLPTLSMRQVVREELCFQDPYRVVFLGSLELQYALPHSLWESIWDIPDRIVFDFAVPRALPSHTVFPHRYMDMDQISDWLREHRKEVNSAHLDSLREVAYRYWNSLNQRLERHDCVGANA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RISB_SHISS
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.