PharMolix/UniProtQA huggingface dataset:
Protein: KC1D_HUMAN
Sequence: MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
What is the function of this protein?
Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms.  It can phosphorylate a large number of proteins.  Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates.  Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2.  Central component of the circadian clock.  In balance with PP1, determines the circadian period length through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation.  Controls PER1 and PER2 nuclear transport and degradation.  YAP1 phosphorylation promotes its SCF(beta-TRCP) E3 ubiquitin ligase-mediated ubiquitination and subsequent degradation.  DNMT1 phosphorylation reduces its DNA-binding activity.  Phosphorylation of ESR1 and AIB1/NCOA3 stimulates their activity and coactivation.  Phosphorylation of DVL2 and DVL3 regulates WNT3A signaling pathway that controls neurite outgrowth.  Phosphorylates NEDD9/HEF1 (By similarity).  EIF6 phosphorylation promotes its nuclear export.  Triggers down-regulation of dopamine receptors in the forebrain.  Activates DCK in vitro by phosphorylation.  TOP2A phosphorylation favors DNA cleavable complex formation.  May regulate the formation of the mitotic spindle apparatus in extravillous trophoblast.  Modulates connexin-43/GJA1 gap junction assembly by phosphorylation.  Probably involved in lymphocyte physiology.  Regulates fast synaptic transmission mediated by glutamate.
What are the official names of this protein?
Casein kinase I isoform delta, CKI-delta, CKId, Tau-protein kinase CSNK1D.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.
Protein: ORR23_ORYSI
Sequence: MRAAEERKGVVPAARRRDQFPVGMRVLAVDDDPVCLKVLETLLLRCQYHVTTTNQAAIALKMLRENRDMFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSVNGETKTVLKGITHGACDYLLKPVRIEELRNIWQHVIRRKFSTRDRANLDFYEECNKPPNADSDHVHGHVTCGSPDQSGRPSKKRKEYCSEEEDEGEVNTQDIDDPSAPKKPRVVWSVELHRKFVAAVNQLGIDKAVPKRILELMNVEKLTRENVASHLQKYRLYLKRLSAVASQQVSIVAALGGRDPFLHMGGFEGLQGYQAFTSSAALSSFTPHGLLNSPRNNPAALGTQGVPASKSIQTMSGSHTLSHSINDANKYHLSLPGNQKGNLGQGLAASLGQTQMQQKWIHEETDDLSTILSGNGLSNGMSGTLQSVTSSPLLPQELAECTQAKIVSQPSIRTSSVSSEHIEGAVGVSSGLLESRVSQQSTIPLSGFSANGLLIHGSFNNTCANKLGGTSSSCAPARSSNDLMVARDTKGGASSFGGAMLLPPDTEQKYLNFGGGNGLKQKFDDRTADSLFDPKFVWSSVPSSQLASNIGAHHAMSQRWNNSSSNSSNIGARMIGQATSSGSTVIPQMKTDFLVSGDMAMPKNASDLSIPKLQSELSSSSCSFDGLLNSIVKVEKDDVTFSDDLGCGDFYSLGACI
What is the function of this protein?
Transcriptional activator that binds specific DNA sequence.  Functions as a response regulator involved in His-to-Asp phosphorelay signal transduction system.  Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes.  May directly activate some type-A response regulators in response to cytokinins.
What are the official names of this protein?
Two-component response regulator ORR23.
What is the protein family that this protein belongs to?
Belongs to the ARR family. Type-B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: EX7L_LEGPL
Sequence: MSSQLPILTVSQLNRQVKGFLENEIGLVHVEGEISNLSKPSSGHYYFTLKDSTAQIRCAFFKNRHSSSLLRNFNDGQQIVASGKLSLYEARGEYQLIVEEIVEAGMGILYQRFEELKIKLAREGLFNPERKKTLPRIPETIGIITSPTGAAIQDILSTLARRFPIARIIIYPSEVQGQAAPQQLVNALKLANTHKRCQVLILARGGGSIEDLWAFNDEYLARQIAISEIPVVSGIGHETDFTIADFVADYRAETPTAAATAVTPNCIELFNILDTAIYRLHDAIIRLVKGLQLKLNHLIDKIASPRQTISTYWQTLDYLERQLISAMTQFINLNINKMNLFSTRLQANNPKTQIERTKIQLRQLILQLTQEIRIKVNQLKHQLSTNLSTLHAVSPLATLDRGYAIVSKNQRILFAAQQAQIGDTIDVRLAKGSLACEVTQIKD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_SINMW
Sequence: MPSLKDLKNRIASVKATQKITKAMKMVAAAKLRRAQEAAEAARPYSQRMAAVLSNIAQAVGADDSAPRLMTGTGKDDTHLLVVCTAERGLCGGFNSQIARHARDHVRKLLAQGKTVKIICVGKKGFDILRREFASLIIDRVDLREVKKIGFENADRIGHKVIELFDNGEFDVCTLFYSEFKSVISQIPTAQQLIPASAGEAVAEGASAIYEYEPDAAAILSDLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGEMINKLTLNYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CBIN_METM7
Sequence: MEFKHVLMILGVIILTLAPLIMYSGLGEDEGYFGGADGAAGDLIMEISPNYEPWFEPFWEPPSGEIESLLFALQAAIGALIIGYFFGYNKAKYDDQN
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRHY_RABIT
Sequence: MSPLLKSIIDIIEIFNQYASHDCDGAVLKKKDLKILLDREFGAVLQRPHDPETVDVMLELLDRDSDGLVGFDEFCLLIFKLAQAAYYALGQASGLDEEKRSHGEGKGRLLQNRRQEDQRRFELRDRQFEDEPERRRWQKQEQERELAEEEEQRKKRERFEQHYSRQYRDKEQRLQRQELEERRAEEEQLRRRKGRDAEEFIEEEQLRRREQQELKRELREEEQQRRERREQHERALQEEEEQLLRQRRWREEPREQQQLRRELEEIREREQRLEQEERREQQLRREQRLEQEERREQQLRRELEEIREREQRLEQEERREQRLEQEERREQQLKRELEEIREREQRLEQEERREQLLAEEVREQARERGESLTRRWQRQLESEAGARQSKVYSRPRRQEEQSLRQDQERRQRQERERELEEQARRQQQWQAEEESERRRQRLSARPSLRERQLRAEERQEQEQRFREEEEQRRERRQELQFLEEEEQLQRRERAQQLQEEDSFQEDRERRRRQQEQRPGQTWRWQLQEEAQRRRHTLYAKPGQQEQLREEEELQREKRRQEREREYREEEKLQREEDEKRRRQERERQYRELEELRQEEQLRDRKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQELRQERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERERKLREEEQLLRREEQLLRQERDRKLREEEQLLQESEEERLRRQEREQQLRRERDRKFREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLQEREEERLRRQERERKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERDRKLREEEQLLRQEEQELRQERDRKLREEEQLLQESEEERLRRQERERKLREEEQLLRREEQELRRERARKLREEEQLLQEREEERLRRQERARKLREEEQLLRREEQELRQERDRKFREEEQLLQEREEERLRRQERDRKFREEERQLRRQELEEQFRQERDRKFRLEEQIRQEKEEKQLRRQERDRKFREEEQQRRRQEREQQLRRERDRKFREEEQLLQEREEERLRRQERARKLREEEQLLRREEQLLRQERDRKFREEEQLLQESEEERLRRQERERKLREEEQLLQEREEERLRRQERARKLREEEQLLRQEEQELRQERARKLREEEQLLRQEEQELRQERDRKFREEEQLLRREEQELRRERDRKFREEEQLLQEREEERLRRQERARKLREEEEQLLFEEQEEQRLRQERDRRYRAEEQFAREEKSRRLERELRQEEEQRRRRERERKFREEQLRRQQEEEQRRRQLRERQFREDQSRRQVLEPGTRQFARVPVRSSPLYEYIQEQRSQYRP
What is the function of this protein?
Intermediate filament-associated protein that associates in regular arrays with keratin intermediate filaments (KIF) of the inner root sheath cells of the hair follicle and the granular layer of the epidermis.  It later becomes cross-linked to KIF by isodipeptide bonds.  It may serve as scaffold protein, together with involucrin, in the organization of the cell envelope or even anchor the cell envelope to the KIF network.  It may be involved in its own calcium-dependent postsynthetic processing during terminal differentiation.
What are the official names of this protein?
Trichohyalin.
What is the protein family that this protein belongs to?
Belongs to the S100-fused protein family.
Protein: IL16_MACFA
Sequence: MDYSFDTTAEDPWVRISDCIKNLFSPIMSENPGHMPLQPNASLSEEDGTQGHPDGNPPKLDTANGTPKVYKSADRSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQPAPASREHLGPHIRASSSSSIKQRISSFETFGSSQLPDKGAQRLSLQPSSGEAAKPLGKHEGGRFSGLLGRGAAPTLVPQQPEQVLPSGSPAATEARDPGVSESPPPGLQPNQKTLPTGSDPLLRLLPTQTEKSQGPVLKMPSQRARSFPLTRSQSCETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSLSCAQTPCIPKEGASPTSSSNEDSAANGSAETSASDTGFSLNLSELREYTEGLTEAKEDDDGDHSSHQSGQSVISLLSSEELKQLIEEVKVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVITVHKVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHNDALAILRQAREPRQAVIVTRKLTAESMPDLNSTTDSAASASAASDVSVESSAEATVYTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETIQPGDEILQLAGTAMQGLTRFEAWNIIKALPDGPVTTVIRRKSLQPKETTAAADS
What is the function of this protein?
Pro-interleukin-16 is involved in cell cycle progression in T-cells.  Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene.  May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells (By similarity).
What are the official names of this protein?
Pro-interleukin-16.
What are the subcellular locations of this protein?
[Interleukin-16]: Secreted. SUBCELLULAR LOCATION: [Pro-interleukin-16]: Cytoplasm. Nucleus.
Protein: TSGA_EDWI9
Sequence: MTDSNRIRLTWISFFSYALTGALVIVTGMVMGNIAEYFNLPISSMSNTFTFLNTGILVSIFLNAWLMEIIPLKRQLVFGFILMILAIAGLMVGHNLAIFSACMFVLGVVSGITMSIGTFLITHIYTGRQRGSRLLFTDSFFSMAGMVFPIIAATLLAQHVAWYWVYACIGVLYLAIFILTLCSDFPQLGKQAVGDSQPVRKEKWGIGVLFLSIAALCYILGQLGFIQWVPEYAAKRFGMSIEESGGLVSNFWTAYMVGMWFFSVALRFFDLQRIVTVLAALSTFMMYMFVSSQQSAMLSMYILGLGFVSSAIYTTLITLGSQQTKVSSPKLVNFILTCGTIGTMLTFVVTGPIVAHSGAHAALATANGLYLVVFVMCVLLGFVTKHRLHGHAAK
What are the official names of this protein?
Protein TsgA homolog.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RNZ_STRGC
Sequence: MQLQFLGTGAGQPSKARNVSSLVLKLLEEINEVWMFDCGEGTQHQILETTIKPRKISKIFITHLHGDHIFGLPGFLSSRSFQANEEQTDIEIYGPKGIKNFVMSSLRVSGSRLPYRIDFHEFDENSLGKILETDKFTVYADKLDHTIFCVGYRIMQKDLEGTLDADKLRAAGVPFGPLFGKVKNGQDIVLEGGTKIIAADYISAPRPGKTITILGDTRKTDSSVRLAVAADVLVHEATYGKGDEKMARKHGHSTNMQAAEVAKEAGVKQLLLNHVSARFLSKDISVMRQDASTVFENVHVVKDLEEVEI
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: METK_HELHP
Sequence: MKKSFLFTSESVTEGHPDKMADQISDAVLDYIIERDKKARVACETLVSNGFCVIAGELKTSVYAPMQEIARKVVQEIGYTDALYGFDYRSAAVLNGIGEQSPDINQGVDREDGEIGAGDQGLMFGYACKETPSLMPLPIWLSHRLTEGLAKKRKDGTLPFLRPDGKSQVTVRYEDGKPVSIDTIVISTQHSPETQQSHLKDAVIEEIVQKVLPQEYLNDNIRYFVNPTGKFVIGGPQGDAGLTGRKIIVDTYGGSCPHGGGAFSGKDPSKVDRSAAYAARYVAKNLVASGVCDKAIVQVAYAIGVVEPVSILVDTQGTGKVEDSKLTECVKAVFRLTPKGIIESLDLLRPIYRKTAAYGHFGRELNEFSWEKTDKVEAIKDFCGIK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RCF2_YEAST
Sequence: MKILTQDEIEAHRSHTLKGGIEGALAGFAISAIIFKVLPRRYPKFKPSTLTWSIKTALWITPPTVLTAICAEEASNNFDATMYGSGSSSEDALDEHRRWKSLSTKDKFVEGLSNNKYKIITGAWAASLYGSWVIVNKDPIMTKAQKIVQARMYAQFITVGLLLASVGLSMYENKLHPNKQKVNEMRRWENALRVAEEEERLEKEGRRTGYVSNEERINSKIFKS
What is the function of this protein?
Assembly factor that plays a role in the assembly of the respiratory chain supercomplexes (SCs) composed of ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV).  May be required for late-stage assembly of the COX12 and COX13 subunits (PubMed:22342701, PubMed:22310663).  Required for the generation and maintenance of a normal proton motive force (PMF) across the inner mitochondrial membrane (IMM) by preventing proton leakage through an inactive population of CIV that accumulates when RCF1 and/or RCF2 proteins are absent (PubMed:30683696, PubMed:31591265).
What are the official names of this protein?
Respiratory supercomplex factor 2, mitochondrial, Altered inheritance of mitochondria protein 38.
Protein: GUAA_SINMW
Sequence: MTQTAHPDTVLIVDFGSQVTQLIARRVRESGVYCEIVPFQSAEDGFHRLKPKAVILSGSPASTLDVGSPRAPSVIFESGLPVFGICYGQQTMCAQLGGKVESGHHREFGRAFLEVEKDCPLFEGLWSLGSRHQVWMSHGDRVTALPDGFEVVATSSNAPFAFIADEKRRYYAVQFHPEVVHTPDGAKLIANFVHKIAGIKGDWTMSAYRAKAVEAIRNQVGDKKVICALSGGVDSSVAALLIHEAVGDQLTCILVDHGLMRKDEAANVVAMFKEHYNLHLLHVDASDRFIGELEGVSDPETKRKIIGRLFIEVFEEEAGKLGGADFLAQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMNMQLVEPLRELFKDEVRVLGRELGLPDSFIGRHPFPGPGLAIRCPGGISREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MRAY_OLEA2
Sequence: MLYHFLYPLSAELPLLNVFRYITFRSVWALLTALLITIFIGPRFIRWLKRVKCGQYIQEEVSCHVQKAGTPTMGGLLIGFSLIISVLLWGDLTNVYLWLVMLVFTGFGLVGFLDDYTKLRRKTNQGLTARSKFLWQMVIAAVAMYFLVKEPAYSTVLSFPFFKNLQPDLGWFYIPFAMIVLVGSSNGVNLTDGMDGLAIGPTVVAGIVFSIFIYIAGHSQIAGYLQVPYVPGMGEVTVFCGALIGAGLGFLWFNAYPAQVFMGDVGSLSLGGALGFLAVLCKQELIMLVAGGLFVLESLSVILQVGYFRMTGGKRIFRMAPLHHHFELKGIPESKIIIRFWIMSIVFGLMALSVLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EFP_STRP7
Sequence: MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRDVRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENELLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLVVNVPDFIEAGQKLVINTAEGTYVSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_GEOUR
Sequence: MRINVESLSSIKKKINFEIPSERVASEVEKAYGEIRKHAAIKGFRKGKVPKDLLVKHFSDKMADDVLKNIINDTYFKALMDENIYPVSHPVIESDELKVGESFKYSATVEIFPDVVVKDYTGLEVKKEKYVFNEEVIANRLKEMQENMSHLEPADAQHSAMNGDFVTFDFKGFVGGEPFDGGAAEDYQLELGSGRFIPGFEDQIVGMKVGDEGEIKVTFPENYGQKDLAGKEATFAVTIKEIKVKELPELNDDFAKDFGEFESLDQLKAKISEVYALQENERIETELRERLIKALIDKNNFEVPETLIDKQLNLMLENSKKRLAMQRLTMEMMGLNDEGYKIQFRSVAETQVKGSLLLEALARQESIQVADDDLDAKIKEIAAQNNQELETVNNFYQQNAQAKENLTAQLKEDKVVDFLLAKAKIDEVDRSEI
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: FBSP1_DROYA
Sequence: MVDPVAALCNYNVLEVIFSYLELEDLNHCSQVCKSWYHFLNDENSDVWRWHCLNKLPKEALKSDLLASVSTYKTKLRAYFHAWSPNDCSRNVYIKPNGFTLHRNPVAQSTDAARSKIGFRHGRHTWEVIWEGPLGTVAVIGISTKEAALQCHGYVALLGSDDQSWGWNLVENHLLHNGDMQGSYPLLNNAPKYQVGERIRVILDCEDNTLSFEKNYEFLGVAFRGLPDKKLYPTVSAVYGNTEVSMVYLGTPLDG
What is the function of this protein?
Required in the presynaptic motoneuron to down-regulate the levels of wnd and restrain synaptic terminal growth at the neuromuscular junction (NMJ).
What are the official names of this protein?
F-box/SPRY domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the FBXO45/Fsn family.
What are the subcellular locations of this protein?
Synapse.
Protein: MUTS_ELUMP
Sequence: MQESKQLTPLMRQYNDIKSKNTDLIVFFRLGDFYEMFDSDAREASRILGIALTQRGGVPMCGVPYHAAANYISKIIKEGRKVGICEQVGTGEGKSKLFERKIVRVITPGTVIEDNMLQSNVSNYLVCVFTDKKGWGAAAIDVSTGEFWVTEQADDISLNGLSCMLAALNPAEILLDKITLDRVKSSMMIPGSVATTIVPREESSQIPSNWPSQSVWAGKKTALTCALTAIKYINVNEPGFKDLLIPFYKEISDYLALDENAVRTLELVSQNGARKGSLWHLLDFTVTPMGGRTLKNWILNPLLNLADIEKRQNCVSNFYDNPLAYEELKVILADISDIERIMSRVGTGNAGPRDLAGLARSLAVHGALKNWFDKYGAVVPYLKENILSKITVIEDLANLLNSAIEPNPPIKISDGGIIKQGFNAELDDLRNTKNNSSKTLAELCEREKAKTGISTLKVGFNSVFGYYIEVSKGQSGKVPFSYTRKQTLTNAERFITEELKEIEDKILHAEEKILRLETSLFDSVRKHLAEHIGVMRSFAKAIAELDVYSNLAHCAKVYKFTKPVIDESNILKAADLRHPVVEACLPLGSFVPNDIDLGGETQISVITGPNMGGKSVYLKQAAVLVILAQMGSFVPAASAHVGIVDKIMTRIGAQDAIAMGQSTFMVEMKETSHILASCTPKSLILLDEVGRGTSTFDGISIAWAITEFLYKPHGGGAKVLFATHYFELTDLENKYKGIKNFHAEVQEYKDADGQSKIAFLYKIKEGAGDKSYGIHVGELAGLPATVIVRAKKVIKDLEAKKGTSVSKKEDDIVGDLFSSPIVEEIKLVNTDAVTPMQALQMILEWKKRINS
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: Y2891_MYCTU
Sequence: MAKSPARRCTAKVRRVLSRSVLILCWSLLGAAPAHADDSRLGWPLRPPPAVVRQFDAASPNWNPGHRGVDLAGRPGQPVYAAGSATVVFAGLLAGRPVVSLAHPGGLRTSYEPVVAQVRVGQPVSAPTVIGALAAGHPGCQAAACLHWGAMWGPASGANYVDPLGLLKSTPIRLKPLSSEGRTLHYRQAEPVFVNEAAAGALAGAGHRKSPKQGVFRGAAQGGDIVARQPPGRWVCPSSAGGPIGWHRQ
What are the official names of this protein?
Uncharacterized protein Rv2891.
Protein: SPEB_SODGM
Sequence: MTTLGHNYDNSLVSNAFGFLRLPLEFNPYATDADWVITGIPFDMATSGRAGCRHGPAAIRQVSTNLAWEGCRWPWDFDVRKRLKVVDCGDLVYEFGDAQDFCDKLQDHAERLLAAGKRMLSFGGDHFVTLPLLCAHAKHFGKMALVHFDAHTDTYANGSKFDHGSMFYHAPNEGLISPAHSVQIGIRTEFERDNGFTVLDAGQVNDRSVDDILAQVKQIVGNLPVYLTFDIDCLDPSAAPGTGTPVIGGLTSDRALKLVRGLQPLNIVGMDIVEVAPAYDQAQITALVAATLALEMLYIQGAKRGDD
What is the function of this protein?
Catalyzes the formation of putrescine from agmatine.
What are the official names of this protein?
Agmatinase, Agmatine ureohydrolase, AUH.
What is the protein family that this protein belongs to?
Belongs to the arginase family. Agmatinase subfamily.
Protein: LSG1_SCHPO
Sequence: MVLPKSKNQIGLGRAIQSDFTKNRRNRKGGLKHIVDSDPKAHRAALRSVTHETDLDEFLNTAELGEVEFIAEKQNVTVIQNPEQNPFLLSKEEAARSKQKQEKNKDRLTIPRRPHWDQTTTAVELDRMERESFLNWRRNLAQLQDVEGFIVTPFERNLEIWRQLWRVIERSDVVVQIVDARNPLFFRSAHLEQYVKEVGPSKKNFLLVNKADMLTEEQRNYWSSYFNENNIPFLFFSARMAAEANERGEDLETYESTSSNEIPESLQADENDVHSSRIATLKVLEGIFEKFASTLPDGKTKMTFGLVGYPNVGKSSTINALVGSKKVSVSSTPGKTKHFQTINLSEKVSLLDCPGLVFPSFATTQADLVLDGVLPIDQLREYTGPSALMAERIPKEVLETLYTIRIRIKPIEEGGTGVPSAQEVLFPFARSRGFMRAHHGTPDDSRAARILLKDYVNGKLLYVHPPPNYPNSGSEFNKEHHQKIVSATSDSITEKLQRTAISDNTLSAESQLVDDEYFQENPHVRPMVKGTAVAMQGPVYKGRNTMQPFQRRLNDDASPKYPMNAQGKPLSRRKARQLTALELGVSPEALSSATSKKHNKKNKRSKQRSGVVIDDY
What is the function of this protein?
GTPase required for the nuclear export of the 60S ribosomal subunit.  Acts by mediating the release of nmd3 from the 60S ribosomal subunit after export into the cytoplasm (By similarity).
What are the official names of this protein?
Large subunit GTPase 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. LSG1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_STRPZ
Sequence: MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTLLAANQKDLANAKEHGISDIMMDRLRLTSERIKAMAQGVQQVADLADPIGQVIKGYTNLDGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKLIRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVPVIETGVGNVHIYVDAQADLDMATKIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLEKAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAIFWINQHTSHHSEAIITRDIKVAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHARGPMGLEALTSTKFYINGDGHIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FARX_LYMST
Sequence: MKTWSHVALLACLSIKWLTCVMADSIYCDDPDMCSNSVDLDRKEFFPLGRHDGVYQTPEEDGDLEDRQTRGDPFLRFGRGDPFLRFGRGDPFLRFGRGDPFLRFGQSDPFLRFGRGDPFLRFGRGDPFLRFGKSDPFLRFGRSDPFLRFGRSDPFLRFGKSDPFLRFGKSDPFLRFGKSDPYLRFGRGDPFLRFGRSDPFFRFGKQQVATDDSGELDDEILSRVSDDDKNIRRKRSTDSAENAHTRHEREASAPRAKGKVGEVKSSDDFQSREIRSKPYMRFGRNNLNNYALEDEDCKLTSDIIDDQFQRYQRGPSRSSFPRYGKRQDKRHDYMRFGRTSGGDFMGYDKSPENVGAEQSR
What is the function of this protein?
SKPYMRF-amide excites neurons.
What are the official names of this protein?
FMRFamide-related neuropeptides.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.