Protein: MPCA_MORAP
Sequence: MVDDDKHAKASSQTSFKIDTGNAHIAQGTFISVNAETGDIIDGLSISIGAIDAKEKVESVVSISEIAAHEIVKTAKNAARPHSPANRGDYPSVVATHGQSGERSYCASPMTRTVSVASSVSTLYPGTSEEELSLDENNKIQADYWSKALADVPAALELPTDRPRPLEPSIVGAEYPFQIGTQLEQLLSSLGEEHDLNLATTILVGWSIVLSRLSGQEDILVGVCGVGEKGLPSSALPVRIDLSGEPNTLQLLGRVRDVLLAAGARGNLSQKNIDLAVLSWQGKGVLSSQAAFYLHDGEANATALDSAAVPFDIELHLYDTTEGASASLRYPPALFDTDTIKRYAGYLIAVLMNMIANGGQSVATIDIVSPAEKKLVLKTWNDSSAEYPSERCVQQLFEDQVEKSPDAIAIVHEGQPFTYLELDALADRIAHKLVHAGIKQGDFVATLLLRSVELVAAQLAVLKIGAAYVPIDPKAPVDRQAFIVEDSASHLLITDVHAEVAPALDLPLLRIDIAELQSREEYSGAIAPTRSSQDTAYVMYTSGSTGRPKGVLVPHKGIARLVINNGFANIRSDDRIVFAANPAFDASTFEVWAPLLNGGTIVTVDADTVADPYRFASVLDQHKITVLFMTPVMLNQHVSTIGSSLAKLRYLISGGEQASTETYTALLRHQGPVRLLNAYGPTEVTMLGTTYEARGGFEKLEKIPIGKPIGNTYTYVLDKHGKPVPMGAVGELYIGGDGVANGYLNRPDLTAERFIPDPFSSTHGARLYRSGDLVRHLPDGNIVFMGRNDDQVKIRGFRIELGEIEARLVEHDLVRESVVLALGEGSEKRLVAYVVAEPTEGLAHALRSHIEERLPVYMIPAAFVRLDAIPVTANGKVDRRALPEPQEDAFARQAYEAPCGETEEAIAAIWSELLGVNQISRHDSFFALGGHSLLVVKMLDRLHRLGLTVSVRVLFESPTLSVLAQDLSKHQAMIIPPNLITLETFKLTPEMLPLIDLKQDDIDRIISQVPGGIHNIQDVYSLAPLQDGILFHHLLATEGDPYLLISHHAFRDRVLVDRYLDAFQRVVDRHDILRTAFFWDALSTPAQVVLRSAPLSVTEHVLDPAAGPVADQLSQRYNHSKYRMDLTQAPLLRFALAEDVDGRWIMAQMMHHLIIDHAAIEVMNAEVEEMLEGREDTLSTPPQFRDLVAQVRAGPTLEEHEHFFAEMLGDIEEPTLPFGLTEVHSNGDEVKEAHMTVPQDLNDRLRAQAKRLGVTLAALCHTAWAQVLARTSGQDHVVFGTLLVGGLQGEQGDQPGMGISINTLPFRCDMDNRSVQECVSQIHSRLAALVEHESASLALAQRCSGVPAGTSLFSSLMNYRHTLMQTTTNDPSNLEFTGKEELVNHEGIEFLGRLERTNYPLAISVEDFGLALGLTAQALQPADPADVCRYMQQALFSLVLALEDAPDMPVSDLDVLPLDERTTLLQLWNATDSPFPENICVHSLFEEQVKQTPMAIAVEHGDQSLTYAELNNRASHLAYQLSAQGIIHGDRVATYLQRSFELIAAQLAILKVGAIYVPIDPKAPLDRQAYIVSDSDSRLVITDENTDVPVAIGAPLFRLTSFHDEKLNTDMDASWRAYSGLNSLKNDIARSSLETAYIMYTSGSTGLPKGVMVAHRGIARLVFNNGFAVITPEDRVAFSMNPTFDPSTFEVWAPLLHGARSVIIDYETFTDAHLLAKALNRHNITFLTLSTALFHQIVYVIGPVLSNLRYIMAGGEQPSTEAFSTLFEHGGRVQMINAYGPTEATVVTTAYVATGSTEAMDRLPIGRPISNTQLYVLDKHRNPVPIGVVGELYVGGPGVANGYLNRPDLTEQRFVVDPFSQAQGARLYKTGDLVRYLRDGNLVFMGRNDDQVKIRGFRIELGEIEERLAEHPQVREVAVLALGESGSKRLVAYVVADAAERLAQTLREHLATSLPEYMIPSAVVRLDAFPLTNNGKVDRRALPVPDLSAFITEDYVPPEGVIETTVAAIWSEVLKIDKVGRYDNFFTLGGHSLLAVRLVNRISTLGAQVPVATLFTSPTLSSFAEAVNTLLQHDDQTLSIIRPVSRDAPLELSFAQQRLWFLAQMPGVSDTYHMPLAMRLKGSVDRSALRKTLNTLFSRHEALRTVFVAVNGQPQVHLLAADTEIEMPFDDLTTENDKDDKLKELTSKAFDAPFDLEKGPLMRARLAQISNDEFVFMLTQHHIVSDGWSMGVLIRELSELYSSFCVGGYDPLEPLDVQYPDYAAWQRRWLAGDRLEEQGSYWRKNLAGSPVSIDLPTDRPRPAEQSFAGAVVPIRINAQLSQALKTLSHKQGTTTFMTALAAWSAVLSRLSGQDDVVIGTPSANRNHQQVERLIGFFVNTLALRIDLSGEPSVEQLLERVRESTVAAQAHQDLPFEQVVEIAQPPRRMDQTPLFQVMFSWQNDDIDSIRMPHLEATLEEVHYEIAKFDLELELYEHNDEIHGSLMYSTALFDASTIERQVGYLEAMLRAMTTDVSQPIEAVDLLGAPEKELLLKTWNQTDKPFPDDRCIHELFEDQAKRSPDAIAVEHDERTVSFRDLSALVNNLTHQLIQAGVKAGDFVPTLLSRSIDLVAAQIAILKAGAAYVPIDPKAPADRQAYIAADSGARLLVTDEHATVTPLIQTPIFRLRKDLAAETEKQELALPAVAARDTAYVMYTSGSTGLPKGVMVSHRAIARLIFNDGYVDMNSDGCMIYGSNPAFDASTAEVWAPLLHGGRMVIVDVETYTDPHRLAAVLDRSKATVLSLTPSLMNHYVSIIGPSLSRLQYLVSGGEQGNLPVYAALLRLGGPVRLVNAYGPTEVTTDTTTYEANADTINQLERLPIGRPICNTQAYVLDKYHNPVPLGAVGELYIGGPGVATGYLNRPDLTAERFLIDPFSQTEGARMYKSGDLVRYLPDSNLIFMGRNDDQVKIRGFRVELGEIEERLVEHQSVREAVVLAVGEGSDKRLIAYVISEPLHQLPHVMREYLAASLPEYMIPAAFVRLESMPLTNNGKVDRRALPEPGSDAFVSREYEEPQGEIETTLAATWSELLKIDKIGRQDNFFMLGGHSLLAVQMIEQLRRMGLVMSVRALFETPVLNVLATSICRESVVREAPTTPANLITHATTKVTPDLLPLIDLQQDDIDRIIDQVPGGVANIQDIYSLSPLQDGILFHHMMATEGDPYLLTICTAFRNRDLLDRYLGAIQRIVDRHDILRTAIVWRNMTTPAQVVLRNAAISVTELTLDPADGPIIEQLKQRYDDRKYRIELDVAPLNRYAFAQDVDGRWIMVQMLHHIIGDHSTMEIMEEEIEKILAGHGDTLAEPQPFRNLIAQVRMGKTVEEHEQFFSKMLSDFDTPALPYGLSDVHREGADVKEHHLMLPQDLNDRLRTQAKRLGVSLASLCHLAWAQVIAATSGQQHVVFGTVLFGRMQGGSGADRAMGLFINTLPLRVDVENATVIESVRRVQTDLATLLEHEHASLALAQRCSSIPSGSPLFSAILNYRHNVVLPEQAELNTGIELLDGQERSSYPFVMSVEDFGDSLGVTAQIVEPHDSLGICGYMQQALLSIVHALEQSPESPVHALSILSSEERDLMVRVWNNTHAEFPADRRIHQLFEDHAALSPEAIALVLDDQSLTYDELNVRANVLAHRLIEQDVRHGDYVALLLHRSFDLVAAQLAVLKVGAAYVPIDSKAPVDRQAYIVKDSASRLLITDAQMSVPSALEVQLLRLDSTDSVLAESDNIALAGSSQDTAYAMYTSGSTGLPKGVMVPHRAISRLVINCGYANIGPEDRVAFAANPAFDASTFELWAPLLNGGCAVIIDADTFTDSHLLAKALERHRINTLWLTMALFNQYVLSIGPALAKLKYLLCGGEQGNLETFAALLKHGGPENLINGYGPTETTTFATTFNASGMDDHFDRLPIGRPIGNTQVYVLDKHCNLVPLGATGELYIGGAGVATGYLAQPNLTAERFLPDPFSEDENARMYKTGDLVRYLPDGNLVFMGRNDEQVKIRGFRIELGEIEARLVEHELVKEAVVLALGEGGDKRLVAYVAADPNEQLALTLRTHLATNMPDYMVPAAFVRLDTLPVTNNGKVNRRALPKPDSSAFAAQGYEEPRGEVEKALATIWTQLLKMERVGRNDNFFMLGGHSLLAVQMIEQLRRIGLSLSVRALFDTPVLSVLAASLNTHHSAPKTPANLITAATTAITPDLLPLINLTQGDIDRIVDQIPGGVANIQDIYSLSPLQDGILFHHMMATEGDPYLLIAGFTFRTKELLDRYLVAVQQIVDRHDILRTAIVSQNMTVPAQVVVRKAAISYTELTLDPADGPLSDQLMQLYDTRKYRIELHNAPLVRFVYSKDVDGRYVMVQLLHHIIGDHSTMEIMEEEIETILAGEEDTLAAPQPFRNLIAQVRMGKTIQEHEQFFSKMLSDIDTPALPYGLSDVHREGADVTETHLMLPQDLNDRLRSQAKRLGVSLASLCHLAWAQVIAATSGQQHVVFGTVLFGRMQGGSGADRAMGLFINTLPLRVDVENATVLESVRRVQTDLATLLEHEHASLALAQRCSSIPSGSPLFSAILNYRHYAAPPVETATDNGIVAIEGNERTNYPFTLSVEDFVSAFGVTVQVVQPYDSLSICGYMQQALQSLADALEHSPDAPIQGLKVLPAEEQDLLVHSWNQTGAAFPADQCVQHVFESQVIERPEAIAMVHGDQTLTYRELNTRANSLAQRLVEAGVNPGDFVSTLLVRSFDLVTVQLAIVKAGAAYVPIDIKSPADRQAYIASDSGAKLLVTDEHTVVHESIEIPIFRLGQVETKDSSQQDWPLSFREGGSSLDAAYVMYTSGSTGMPKGVMIPHRGITRLVINNGHANYGPDDRVVFGANPAFDASTMEVWAPLMNGGRLVIVDAGTYTDPEKLACLLEQQAVTVLFLTTALLNHYVPIIGRSLSKLKYLISGGEQGSLHAYTSLLRLGGRVRLINGYGPTESTTIATTYEPTLHHLGQLENLPIGRPIANTQVYVLDKYFRPVPTGATGELYIGGAGLAIGYLNRPDLTAERFLPNPFSDCEGARMYRTGDLVKYLPDGNLVFMGRNDEQVKIRGFRIELGEIEARLVEHELVKQAVVLALGNGGDKRLVAYVVADHSEELVHTLRAHLTATMPEYMIPAALVRLDALPVTNNGKVNRRALPEPEASAFAVRSYEAPKGDVEIGLAEIWAELLSLDRVGRHDNFFMLGGHSLLAVRMSGSVRSRLGLDLKLHTLFAAPTITDLAQKLLQEASSDDDEYSVIFPLKTTGTRPPLFCVHSGIGLSWPYIGLVKHLHPDQPVYGIQARGLDRKTKLATSVEEMTEDYIEQIRRIQPHGPYHFLGWSFGGTVAHSMATELEKQGEQVPLLVIMDSTADYSIVADVQIDDTEVGANLEHLIRFGGEFSAEDGGAMWERTKPINDNSFVLAMKFKPSVYSGDILFFRATLQEDELTPMVDPLSWTPYLAGAIEVHDVECTHIEMDKPAPMTIIGQTVASKLERAL
What is the function of this protein?
Nonribosomal peptide synthetase that catalyzes the biosynthesis of the cyclopentapeptides malpicyclins, natural products that show a moderate antibacterial activity against Gram-positive bacteria as well as biosurfactant activities (PubMed:33158886) (Probable).  Modules 1 and 2 show promiscuous adenylation leading to the parallel production of multiple products from one NRPS assembly line, including malpicyclin A corresponding to cyclo(-D-Leu-L-Tyr-D-Arg-D-Val-L-Leu-), malpicyclin B corresponding to cyclo(-D-Ile-L-Tyr-D-Arg-D-Val-L-Leu-), malpicyclin C corresponding to cyclo(-D-Leu-L-Phe-D-Arg-D-Val-L-Leu-) and malpicyclin D corresponding to cyclo(-D-Val-L-Phe-D-Arg-D-Val-L-Leu-) (PubMed:33158886).
What are the official names of this protein?
Malpicyclin synthetase, Nonribosomal peptide synthetase mpcA, NRPS mpcA.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.