PharMolix/UniProtQA huggingface dataset:
Protein: ABA1_ASCSU
Sequence: TMEHYLKTYLSWLTEEQKEKLKEMKEAGKTKAEIQHEVMHYYDQLHGEEKQQATEKLKVGCKMLLKGIIGEEKVVELRNMKEAGADIQELQQKVEKMLSEVTDEKQKEKVHEYGPACKKIFGATTLQHHRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKTKKELEAKILHYYDELEGDAKKEATEHLKGGCGEILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKAKKELEAKILHYYDELEGDAKKEATEHLKGGCAEILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKTKKDLQAKILHYYDELEGDAKKEATEHLKDGCREILKHVVGEEKEAELKKLKDSGASKEEVKAKVEEALHAVTDEEKKQYIADFGPACKKIFGAAHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKAKKELEAKILHYYDELEGDAKKEATEHLKGGCREILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKAKKELEAKILHYYDELEGDAKKEATEHLKGGCREILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKAKKELEAKILHYYDELEGDAKKEATEHLKGGCREILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKAKKELEAKILHYYDELEGDAKKEATEHLKGGCREILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKAKKELEAKILHYYDELEGDAKKEATEHLKGGCREILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRHHFTLESSLDTHLKWLSQEQKDELLKMKKDGKAKKELEAKILHYYDELEGDAKKEATEHLKGGCREILKHVVGEEKAAELKNLKDSGASKEELKAKVEEALHAVTDEEKKQYIADFGPACKKIYGVHTSRRRRYHAEDGTDDIDGLAQSRQRRSGFFEKLIDVFAFF
What is the function of this protein?
Has high binding affinity for fatty acids and retinoids.
What are the official names of this protein?
Polyprotein ABA-1, Body fluid allergen 1, Nematode polyprotein allergen ABA-1, NPA ABA-1.
What is the protein family that this protein belongs to?
Belongs to the NPA family.
Protein: MSRA_BRUSU
Sequence: MSFFDSYRKKMQMPSKEEVLPGRVQPIPTAAAHFVSGHPLKGPWPDGMKQVLFGMGCFWGAERLFWQVPGVYVTAVGYAGGITPNPTYEETCTGLTGHAEVVLVVYDPKVVTLNELLALFWEEHDPTQGMRQGNDIGTTYRSVIYTFNAVDRAVAEKSRDAYSQALASRGLGPVTTQIADAPDFYYAEDYHQQYLAKNPDGYCGLRGTDVSCPIPLAH
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: PSBT_PROMT
Sequence: MEAFSYVLILTLALVTLFFAVAFRDPPKYDK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: TM130_HUMAN
Sequence: MAQAVWSRLGRILWLACLLPWAPAGVAAGLYELNLTTDSPATTGAVVTISASLVAKDNGSLALPADAHLYRFHWIHTPLVLTGKMEKGLSSTIRVVGHVPGEFPVSVWVTAADCWMCQPVARGFVVLPITEFLVGDLVVTQNTSLPWPSSYLTKTVLKVSFLLHDPSNFLKTALFLYSWDFGDGTQMVTEDSVVYYNYSIIGTFTVKLKVVAEWEEVEPDATRAVKQKTGDFSASLKLQETLRGIQVLGPTLIQTFQKMTVTLNFLGSPPLTVCWRLKPECLPLEEGECHPVSVASTAYNLTHTFRDPGDYCFSIRAENIISKTHQYHKIQVWPSRIQPAVFAFPCATLITVMLAFIMYMTLRNATQQKDMVEVADFDFSPMSDKNPEPPSGVRCCCQMCCGPFLLETPSEYLEIVRENHGLLPPLYKSVKTYTV
What are the official names of this protein?
Transmembrane protein 130.
Protein: LRP6_MOUSE
Sequence: MGAVLRSLLACSFCVLLRAAPLLLYANRRDLRLVDATNGKENATIVVGGLEDAAAVDFVFGHGLIYWSDVSEEAIKRTEFNKSESVQNVVVSGLLSPDGLACDWLGEKLYWTDSETNRIEVSNLDGSLRKVLFWQELDQPRAIALDPSSGFMYWTDWGEVPKIERAGMDGSSRFVIINTEIYWPNGLTLDYQERKLYWADAKLNFIHKSNLDGTNRQAVVKGSLPHPFALTLFEDTLYWTDWNTHSILACNKYTGEGLREIHSNIFSPMDIHAFSQQRQPNATNPCGIDNGGCSHLCLMSPVKPFYQCACPTGVKLMENGKTCKDGATELLLLARRTDLRRISLDTPDFTDIVLQLEDIRHAIAIDYDPVEGYIYWTDDEVRAIRRSFIDGSGSQFVVTAQIAHPDGIAVDWVARNLYWTDTGTDRIEVTRLNGTMRKILISEDLEEPRAIVLDPMVGYMYWTDWGEIPKIERAALDGSDRVVLVNTSLGWPNGLALDYDEGTIYWGDAKTDKIEVMNTDGTGRRVLVEDKIPHIFGFTLLGDYVYWTDWQRRSIERVHKRSAEREVIIDQLPDLMGLKATSVHRVIGSNPCAEDNGGCSHLCLYRPQGLRCACPIGFELIGDMKTCIVPEAFLLFSRRADIRRISLETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSDMLGLNREVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQAGWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPSTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNSIRKAHEDGGQGFNVVANSVANQNLEIQPYDLSIDIYSRYIYWTCEATNVIDVTRLDGRSVGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSKLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEPPTCSPQQFTCFTGDIDCIPVAWRCDGFTECEDHSDELNCPVCSESQFQCASGQCIDGALRCNGDANCQDKSDEKNCEVLCLIDQFRCANGQCVGKHKKCDHSVDCSDRSDELDCYPTEEPAPQATNTVGSVIGVIVTIFVSGTIYFICQRMLCPRMKGDGETMTNDYVVHSPASVPLGYVPHPSSLSGSLPGMSRGKSMISSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGTYFPAILNPPPSPATERSHYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYAPSRRMTSVATAKGYTSDVNYDSEPVPPPPTPRSQYLSAEENYESCPPSPYTERSYSHHLYPPPPSPCTDSS
What is the function of this protein?
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes.  Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation.  The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalosomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin.  Required for posterior patterning of the epiblast during gastrulation (By similarity).
What are the official names of this protein?
Low-density lipoprotein receptor-related protein 6, LRP-6.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum. Membrane raft. Note=On Wnt signaling, undergoes a cycle of caveolin- or clathrin-mediated endocytosis and plasma membrane location. Released from the endoplasmic reticulum on palmitoylation. Mono-ubiquitination retains it in the endoplasmic reticulum in the absence of palmitoylation. On Wnt signaling, phosphorylated, aggregates and colocalizes with AXIN1 and GSK3B at the plasma membrane in LRP6- signalsomes (By similarity). Chaperoned to the plasma membrane by MESD.
Protein: ATPE_GEOSM
Sequence: MAEKLKVELVTPYKKVLSEEVDEITATGALGEFGVLPGHAPFLTSLKIGELAYRKDGVSHHMALNWGYFEVENDTVTVLVETAEKADEIDLERAKAALGRAEVELKALTPEDKNFRIYEAALERALIRVQVAGKATRR
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BR1B_LITST
Sequence: FLPIIAGMAAKVICAITKKC
What is the function of this protein?
Antimicrobial peptide with activity against Gram-negative and Gram-positive bacteria (MIC=50 uM against E. coli, MIC=6 uM against S. aureus) and fungi (MIC=13 uM against C. albicans) (PubMed:15556063).  Shows hemolytic activity on human erythrocytes (HC(50)=25 uM) (PubMed:15556063).
What are the official names of this protein?
Brevinin-1SPb.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Brevinin subfamily.
Protein: SYP_PYRAE
Sequence: MELIREARPHSREKLKSNLIEWFHWLLREAELYDVRYPVKGAYVWRPYGMKIRRNVENLIRKFHDETGHEEVLFPVFIPYEFFGKESQHIKGFEKEVFWVSKGGEAGERLVLRPTSETAIMPMVKLWIQDYKDLPLRVYQIVSVFRAETKMTHPMIRLREISMFKEAHTVHADKEDAERQVREAVEIYKRIFDEMCLAYLINKRPEWDKFAGAEYTIAFDTILPDGRSLQIGTVHYLGTNFTKVFEVTYLDADGTRKLAHTTSYGISERSIAAMLITHGDDGGTTLPPKLAPIQVVVIPIYYGEEEAPLVMPLVRETANRLNEAGIRVYVDERADKTPGWKFYYWELKGVPLRVEIGKRDVEKRQAVIARRDTLEKYAVSINELVDAVKQLMKSVEENLRKRAWEELKGRVVKAEDIEVAKAAIKEGKVVEIPWSGDNDCGIKIQELVGADALGIPLDADASVGGYDLRDLACKERRAELWLRLSERY
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK22_DRIGR
Sequence: MKKHRKKRSSSTQVQALAQHICMSAHKARRVIDQIRGRSYEKTLMLLELMPYRASYPILKLVYSAAANASHNKGFNKADLVISQAEVNGGTIIKKLKPRARGHSYPIKRPTCHINIVLKDQSKTKTQQDFVLENKGVFKDTIIERYPEKEREREREINFFKRLLRFPNWNRDK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYE_YERPY
Sequence: MKIKTRFAPSPTGYLHVGGARTALYSWLFSRHLGGEFVLRIEDTDLERSTQEAIDAIMDGMNWLNLDWDEGPYFQTKRFDRYNAVIDQMLDAGTAYRCYCSKERLEALREAQMANGEKPRYDGHCRDSQCTHGADEPSVVRFRNPQEGSVIFDDKIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVIDDWDMEITHVIRGEDHINNTPRQINILKALGAPVPEYAHVSMILGDDGKKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSIEEMTQLFTLDAVSKSASAFNTEKLQWLNHHYINSLPPEQVAVHLSWHVEQLGIDTRNGPELVEIVKLLGERCKTLKEMAESCRYFYEEFDAFDVDAAKKHLRPVARQPLEAVKVKLAAITEWTTENVHNAIQGTADELGVGMGKVGMPLRVAVTGVGQSPGMDVTVHAIGQARTLARIDKALAFISEREAQQ
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRUP_PSYCI
Sequence: ERTHTGEKPFECPECHKRFTRDHHLKTHMRLHTGEKPYHCSHCDRQFVQVANLRRHLRVHTGERPYACELCDAR
What is the function of this protein?
Krueppel is a gap class segmentation protein.
What are the official names of this protein?
Protein krueppel.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMK_ECO55
Sequence: MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: NUOK_CAUVC
Sequence: MIGLPHYLVVAAILFTIGVFGIFVNRKNVIVILMSIELILLAVNINLVAFSAYLHDVAGQIFAMFVLTVAAAEAAVGLAILVTFFRNRGDIAVDDASMMKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CDD_YERPY
Sequence: MQARFHTSWAELPASLQFALEPILSAENFPAMLTAEQVKTVKNISGLDDDALAFALLPLATACALTPISHFNVGAIARGKSGNFYFGANMEFRGVPLQQTIHAEQCAVTHAWLRGETNLVAITVNYTPCGHCRQFMNELNSGSELHIHLPGRPPSTLGQYLPDSFGPTDLAITTLLMDPVNHGYTLAETDPLTQAALNAANHSHAPYSQSHSGVALETTNGKIYAGRYAENAAFNPSLPPLQAALILANITGENCASIRRAVLVEGHNAVTSQWDTTLATLNALGCSAVKRVTF
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, Cytidine aminohydrolase, CDA.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: SBNO1_RAT
Sequence: MVEPGQDLLLAALSESGISPNDLFDVDGGDAGLATPTPPSVQQQQPPSTTTFVLNQINQLPTLGSTIVMTKTPPATTNRQTITLTKFIQTTANTRPSVSAPAVRNAIPPAPAKDQVQLKDLLKNNSLNELMKLKPPANIAQPVATAAADVSNGAVKKESSNKEVARVWINDMKMRSFSPTMKVPVVREEDEPEEEDEEEMGHAETYAEYMPIKLKIGLRHPDAVVETSSLSSVTPPDVWYKTSISEETIDNGWLSALQLEAVTYAAQQHETFLPNGDRAGFLIGDGAGVGKGRTIAGIIYENYLLSRKRALWFSVSNDLKYDAERDLRDIGAKNILVHSLNKFKYGKISSKHNGSVKKGVIFATYSSLIGESQSGGKYKTRLKQLLHWCGDDFDGVIVFDECHKAKNLCPVGSSKPTKTGLAVLELQNKLPKARVVYASATGASEPRNMAYMNRLGIWGEGTPFREFSDFIQAVERRGVGAMEIVAMDMKLRGMYIARQLSFTGVTFKIEEVLLSQSYVKMYNKAVKLWVIARERFQQAADLIDAEQRMKKSMWGQFWSAHQRFFKYLCIASKVKRVVQLAREEIKNGKCVVIGLQSTGEARTLEALEEGGGELNDFVSTAKGVLQSLIEKHFPAPDRKKLYSLLGIDLTAPSNNSSPRDSAKKARKIGGLTGSSSDDSGSESDVSDNEESDYESSKNMSSGDDDDFNPFRDDNSSLITSQDAVERAQQMKKDLLDKLEKLAEDLPPNTLDELIDELGGPENVAEMTGRKGRVVSNDDGSISYESRSELDVPVEILNITEKQRFMDGDKNIAIISEAASSGISLQADRRAKNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYVFLISELAGEQRFASIVAKRLESLGALTHGDRRATESRDLSRFNFDNKYGRNALEIVMKSIVNLDSPMVSPPPDYPGEFFKDVRQGLIGVGLINVEDRSGILTLDKDYNNIGKFLNRILGMEVHQQNALFQYFADTLTAVVQNAKKNGRYDMGILDLGSGDEKVRKSDVKKFLTPGYSTSGHVELYTISVERGMSWDEATKIWAELTGPDDGFYLSLQIRNNKKTAILVKEVNPKKKLFLIYRPNTGKQLKLEIYADLKKKYKKVVSDDALVHWLDQYNSSADTCTHAYWRGNCKKASLGLVCEIGLRCRTYYVLCGSVLSVWTKVEGVLASVSGTNVKMQIVRLRTEDGQRIVGLIIPANCVSPLVNLLSTSDQSQQLAVQQKQLWQQHHPQSITNLSNV
What are the official names of this protein?
Protein strawberry notch homolog 1.
What is the protein family that this protein belongs to?
Belongs to the SBNO family.
Protein: PDXS_BACCN
Sequence: MTNVTGTERVKRGMAEMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPADIRAAGGVARMADPTIVEEVMGAVSIPVMAKCRIGHLVEARVLESLGVDYIDESEVLTPADEVNHLNKRDYTVPFVCGCRDIGEAARRIAEGASMLRTKGEPGTGNIVEAVRHMRQVNAEIRQVANLREDELMTYAKNTGAPYEVLLEIKRLGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSENPEKFARAIVEATTHYEDYELIANLSKGLGDAMKGVEISTLLPEQRMQERGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: PBL36_ARATH
Sequence: MATKLESFKVVEKLGVEKGEKGKMMSKKKNVKKDGDESESGFWFRFKFIFSCISSRSKVDSSMNATAVIAEPKKVIEKLEGHPAPTKDTGCAESGSSTPLMSGELKYSSKLRIFMFNDLKLATRNFRPESLLGEGGFGCVFKGWIEENGTAPVKPGTGLTVAVKTLNPDGLQGHKEWLAEINFLGNLVHPSLVKLVGYCMEEDQRLLVYEFMPRGSLENHLFRRTLPLPWSVRMKIALGAAKGLAFLHEEAEKPVIYRDFKTSNILLDGEYNAKLSDFGLAKDAPDEKKSHVSTRVMGTYGYAAPEYVMTGHLTTKSDVYSFGVVLLEILTGRRSVDKSRPNGEQNLVEWVRPHLLDKKRFYRLLDPRLEGHYSIKGAQKATQVAAQCLNRDSKARPKMSEVVEALKPLPNLKDFASSSSSFQTMQPVAKNGVRTQGGGFVSRNGPPMRSLSSLNLPQASPYRYARQSPKPKGKEP
What is the function of this protein?
Involved in chitin-triggered immune signaling and is required for reactive oxygen species (ROS) production (PubMed:29907700).  Acts downstream of SD129 in defense signaling triggered by the pathogen-associated molecular pattern (PAMP) 3-OH-C10:0, a medium-chain 3-hydroxy fatty acid (PubMed:31922267).
What are the official names of this protein?
Serine/threonine-protein kinase PBL36, PBS1-like protein 36, Receptor-like cytoplasmic kinase PBL36.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: GATC_RICRO
Sequence: MITKEAAQKIAKLARLKFEEDTVEKFFTQLSTIMDMIDILNEIDCKDIEPLTSVCNMNARMREDAVTSSDLSSELFDNVSGNSTQLAKEVKYFITPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: RLMN_HELPJ
Sequence: MKASIYDFTLDELSQLLKPSFRAKQLYLWLYAKYKTSFKDMQNNFSKDFIAYLEQEFTLRTIEIAHVRESVDGSKKYLFKSLRDNHTFEAVLLKMKDKKIDEETNAVLEGEKYTVCVSCQIGCQVGCSFCFTQKGGFVRDLKASEIIQQALLIKEANNLPIEKALNIVFMGMGEPLNNLDEVCKAVEIFNTGMQISPKRITISTSGVADKIPILAGKNLGVQLAISLHAVDDKTRSSLMPLNKKYNIECVLNEVRKWPLEQRKRVMFEYLLIKDLNDSLDCAKKLLKLLNGIKSKVNLILFNPHEGSKFERPSLESARMFADFLNAKGLLCTIRESKALDIEAACGQLREKKLQQKI
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYK_PICTO
Sequence: MHWSESLLKDVSGDQRISTGISPSGPIHIGNMREILTGDIIYKEALKLGIKASFIYLCDDMDPLRKVYPFLPGSYERYVGHPLSMIPAPDGDKTYSEYFLEPFKETIDKIDVRPEIISTTSLYKNGVLSRAIDIAMNNREKIKNILNSIGNYKITGDWYPYEPVCKSCGRINTTTVISYNYPYAEYKCKCGYTGKADIRTDDGKMPWRVEWPAKWFSLHVTIEPFGKDHGAAGGSYDTGKAIASDIFNINPPLPLLYERIFLKGKGVMHSSTGVVIPASEMIKFSPPEIIRFLIAKNNPGRHIDFDPGPGLLNLIDEYEKYERAYFGLDSVKDDDYKEVYELSRLKILKEPEKITFRHIVTLVQIYNNNDALLSALKRSGYEKDYIDDYIMNEIDTARYWLEKYAPPEMKFSLTDENINLNDDERKIVNEFLENIDNIEWSPDSIHNYVYDIIGRSKMRPQDAFAVFYKILIGRSRGPRLGYFIYNLGREYIIKRFSSILAETF
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_BACC1
Sequence: MKQVQTKRDWKKLAYDVVEEKVITKEDAIAILEADDTEILEIMNAAYIIRHHHFGKKVKLNMIINTKSGLCPEDCGYCSQSIISEAPIDKYAWLTQEKIVEGAHEAIRRKAGTYCIVASGRRPTDKEVNHVIGAVKEIRETTDLKICCCLGFLNEDQAGRLAEAGVHRYNHNLNTHVNNYESICSTHTYDDRVDTVQKAKQAGISPCSGAIFGMGETIEERAEIAFELQRIDADSIPCNFLVAVKGTPLEGQKELTPVECLKVLAMMRFVNPTKEIRISGGREINLRSVQPIGLFAANSIFVGDYLTTAGQEPTADWGMIEDLGFEIEECAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: EFP_MYCSK
Sequence: MASTADFKNGLVLQIDGQLWQIVEFQHVKPGKGPAFVRTKLKNVVSGKVVDKTYNAGVKVETATVDRRDATYLYRDGSDFVFMDSEDYEQHPLPESLVGRAADFLLESMPVQIAFHDGVPLYLELPVTVELLVASTEPGLQGDRSSAGTKPATMETGAEIQVPLFINTGDKLKVDSRDGSYLGRVNA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WNT11_DANRE
Sequence: MTEYRNFLLLFITSLSVIYPCTGISWLGLTINGSSVGWNQTHHCKLLDGLVPDQQQLCKRNLELMHSIVRAARLTKSACTSSFSDMRWNWSSIESAPHFTPDLAKGTREAAFVVSLAAAVVSHAIARACASGDLPSCSCAAMPSEQAAPDFRWGGCGDNLRYYGLQMGSAFSDAPMRNRRSGPQDFRLMQLHNNAVGRQVLMDSLEMKCKCHGVSGSCSVKTCWKGLQDISTISADLKSKYLSATKVIPRQIGTRRQLVPREMEVRPVGENELVYLVSSPDYCTQNAKQGSLGTTDRQCNKTASGSESCGLMCCGRGYNAYTEVLVERCQCKYHWCCYVSCKTCKRTVERYVSK
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  May play a role in the formation of dermal structure in limb buds.  Is likely to signal over only few cell diameters (By similarity).
What are the official names of this protein?
Protein Wnt-11.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: TOM7A_SOLTU
Sequence: MLKPKGKNTKKAAAADEDDGAVAVVGKFVKEWGTWTAKKAKVITHYGFIPLVIIIGMNSEPKPSLSQLLSPV
What is the function of this protein?
Seems to act as a modulator of the dynamics of the mitochondrial protein transport machinery.  Seems to promote the dissociation of subunits of the outer membrane translocase (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM7-1, Translocase of outer membrane 7 kDa subunit 1.
What is the protein family that this protein belongs to?
Belongs to the Tom7 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: EFPL_SHISS
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: ACPS_VIBA3
Sequence: MAVVGLGTDIAEIERVEKALSRSGEAFAQRILTDSEFEVFQQLKQKGRYLAKRFAAKEAASKALGTGIALGVTFHDFEISNDEHGKPVLSLHKKAREIADASGTKSIHLTISDERHYAVATVLLES
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.