PharMolix/UniProtQA huggingface dataset:
Protein: PURT_COREF
Sequence: MFIPEKIGTPLSPNATKVMILGSGELGKEVTIAFQRLGVEVHAVDRYDNAPAHQVAHFSYVIDMTDAAAVRELVTTIKPDFIIPEIEALATDELVRIEQEGLATVVPTARATQLTMNREGIRRLASEELGLPTSGYEFCSTFEEFTAAAERLGYPNVVKPVMSSSGKGQSVVTSAEDLESAWEYAMSGARVSNQRVIVEQFVEFDYEITLLTVRGIDPATGKPATWFCEPIGHRQQDGDYVESWQPMEMTAPALENARSVAARITNALGGRGVFGVELFVSGDDVYFSEVSPRPHDTGLVTLATQRFSEFELHAKAVLGLPVDVTLTSPGASAVIYGGVDSPGVSYAGLAEALAVAETDVRLFGKPEAFTKRRMGVAVSTAEDTATARDRATLAAAAVTVHG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RL20_CHLP8
Sequence: MPKSTNSVASKARRKRILNKAKGYWGSRGNVLTVVKHAVDKAEQYAYRDRRVKKRTFRSLWIMRINAAARQNGVSYSRLMDAIHKKNIEIDRKALAEIAVKDPEAFAMIVKSALD
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: SPSS_METTP
Sequence: MPSSITSKLDKFRCMKRSISEINLDPLQRGGILTPEARAALVEWGDGYSVCDFCEGMLDRVRNPPVEEFVHEILPRFLDVDDVRITHGAREGMYAAMHSLCDAGDYIVADGNAHYTTVLAAERAGLEISYVENSGEPEYTINPEGYREAIRDAADQGYRVSMAVLTYPDGNYGNLVDARRVAEICHEEGVPLLLNGAYSIGRMPVSARELDADIVVGSGHKSMASSGPIGVLGAKQEYADIIFRRSKSKKNKEVELLGCTVRGAGLLTMMASFPHVLERVGRWQEEVDKARWFSSELEELGIEQQGEKPHNHDLMFFKSERLYEISKSARKGRYFLYHELKDRGICGIKPGLTRQFKLSTYLIPREDLERVVSAFHEIIEMGSRVEAE
What is the function of this protein?
Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)).
What are the official names of this protein?
O-phospho-L-seryl-tRNA:Cys-tRNA synthase, Sep-tRNA:Cys-tRNA synthase, SepCysS.
What is the protein family that this protein belongs to?
Belongs to the SepCysS family.
Protein: Y8587_DICDI
Sequence: MAMLWISMFIIMRKYGRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSGSSSNSNRVVVV
What are the official names of this protein?
Putative uncharacterized protein DDB_G0271974.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_HELPJ
Sequence: MEFCVLFGGASFEHEISIVSAIALKGVLKDRIKYFIFLDENHYFYLIEESNMHSKYFAQIKEKKLPPLILTHNGLLKNSFLGAKIIELPLVINLVHGGDGEDGKLASLLEFYRIAFIGPRVEASVLSYNKYLTKLYAKDLGVKALDYVLLNEKNRANALDLIGFNFPFIVKPSNAGSSLGVNVVKEEKELIYALDSAFEYSKEVLIEPFIQGVKEYNLAGCKIKKGFCFSYVEEPNKQEFLDFKQKYLDFSRTKAPKANLSNALEEQLKENFKKLYNDLFDGAIIRCDFFVIENEVYLNEINPIPGSLANYLFDDFKTTLENLAQSLPKTPKIQVKNSYLLQIQKNK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1165_STRU0
Sequence: MKKMAFDSNKYLQLQRDHILERIHQFDGKLYMEFGGKMLEDYHAARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKARGDLGISYDQEVFRLIDTFHSLDIFVGSVVITQYNNQAAADAFRKQLEKNGITSYLHYPIKGYPTDINHIISPEGMGKNDYIKTSRNLVVVTAPGPGSGKLATCMSQMYHDQINGITSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLETYGKTAVNYNRDIEVFPVLNRTFERILSKSPYASPTDMGVNMVGFSIIDDDLAIEASKQEIIRRYYQTLVDFKAERVPETAIKKIELLMNDIGVSPEDRKVTVLARQKAEQTGAPALALELPNGEMVTGKTSDLFGPTAAVVINAIKKLAHISKETHLIEPEYVKPIQGLKVNHLGSQNPRLHSNEILIALAITAMNNDQAHLAMKELGNLKGSEAHSTVTLTEEDRNVLRKLGVNVTFDPVYQHDKLYRK
What are the official names of this protein?
UPF0371 protein SUB1165.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: CDC11_CANAL
Sequence: MNYSTENVSSAALRKRKTLKKSINFSIMIIGESGSGRSTLINTLCGGNSIVPTSSTATQDPFTKKLTLRHENVELEDNEGHKISLNIIDTPNFANSINCDDDFKIIVDFIRHQFDEVLLEESRVKRNPRFKDGRIHVLIYMINPTGHGLSDIDVKFLQHVNNLVNIIPIISKADSLTPKELKLNKELILEDLNNYGINFYKFNEYDYEQDYIDEEIIEYNKYLNSLIPFAIIGANEYRSNPNGSEDEDDILKLRILNKDFKPIDIDNAEINDFTILKNVLLVTHLNEFKDITHDSIYENYRTEALSGKQFQYVNKDSAKQEISESDYLMKEEQIKLEEERLRKFEERVHQDLINKRKELLERENELKEIEKRLLAEGLKFDENGDVVKVHEEESSENEVKVI
What is the function of this protein?
Septins are GTPases involved in cytokinesis that assemble early in the cell cycle as a patch at the incipient bud site and form a ring before bud emergence, which transforms into an hour-glass shaped collar of cortical filaments that spans both sides of the mother-bud neck.  This collar persists until just before cytokinesis, when it splits into two rings that occupy opposite sides of the neck.  The septins at the bud neck serve as a structural scaffold that recruits different components involved in diverse processes at specific stages during the cell cycle.  Many proteins bind asymmetrically to the septin collar.  The septin assembly is regulated by protein kinase GIN4.  Septins are also involved in cell morphogenesis, chlamydospores morphogenesis, bud site selection, chitin deposition, cell cycle regulation, cell compartmentalization, and spore wall formation.  CDC11 is required for the correct localization of SEC3 at bud tips and bud necks.  Plays a key role in invasive growth and virulence.
What are the official names of this protein?
Septin CDC11, Cell division control protein 11.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
What are the subcellular locations of this protein?
Bud neck. Note=Localizes to a tight ring at the bud and pseudohyphae necks and as a more diffuse array in emerging germ tubes of hyphae.
Protein: YG1H_YEAST
Sequence: MTGYEPFKFFSIRMSSINSPSVIFKTIKTFNPGKTEEYRAKKAYVQDKGYLRQKRPCPFYYRIPTCTASKYSIGCASSKKLTYTRTKFKFNLVTQRENSL
What are the official names of this protein?
Uncharacterized protein YGR025W.
Protein: RIMM_SALG2
Sequence: MSKQLAAQVPAEPVVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDLIIKLKGVDDRDAANLLTNCEIVVDSSQLPALEEGDYYWKDLMGCQVVTAEGYDLGKVIDMMETGSNDVLVIKANLKDAFGIKERLVPFLYGQVIKKVDLATRTIEVDWDPGF
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COL_CHICK
Sequence: GLIFNLDTGELCLQSAQCKSECCQEDSGLSLAXC
What is the function of this protein?
Colipase is a cofactor of pancreatic lipase.  It allows the lipase to anchor itself to the lipid-water interface.  Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
What are the official names of this protein?
Colipase.
What is the protein family that this protein belongs to?
Belongs to the colipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: TM140_MOUSE
Sequence: MAFSRLWRNNHLPFVGIMILLAAALCLMFYALLWKAGNLADLPSLRIGFYNFCLWKEDMGSLACYNFPELDVLGIPQVGLALARLGVYGALVLTVFVPLPLLLAQYNRDEGEWRLAVCFLAASSILLAGGLSLFLSFVWKWLRLSFLGPALPALCLAQLLLIFLLVATVRFPPRDKEDKNQWENC
What are the official names of this protein?
Transmembrane protein 140.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MENG_PARUW
Sequence: MSTYNKNRPQTIQIMFNSIAKQYDRTNAVLSFCLHRRWNLELVKKVQSQQTSHTLLDLCAGTGDVAFSYLNQVSAPCQAYLVDFSSEMLACAEEKAKSFGKTPHSFQYVLADVQRLPFSNQTMDCATMAYGIRNIHHPLQSLQETYRVLKPGGCLGILELTRPENKFLQIGHQLYLKTLLPLLGKWLTANENAYQYLRKSIHTFIPPGELEELVKTAGFINTGRYSLAGGIATIITGFKPMK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: EFG1P_CANGA
Sequence: MSGVRMQKKNRRALGQSLEMAQFLDSGSNKIKRRIRDLERLLKKKKDILPSNIIVEKERTLEALRLELHNHEVKENIRKNAKKYHMVRFFERKKALRRYKKALKTYKADENEANKEALENAEVDLCYVVNFPKSEKYISIFTEDDTEASAETNLRRKAFRQLVRGKIADKSLPVSLSNILAGKKLSEEAIGVTLDDALSRSNQTDASHQESDEDSDSNENEKEEDDFFE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL15_HAEIE
Sequence: MRLNTLSPAEGAKHSAKRLGRGIGSGLGKTGGRGHKGQKSRTGGGVRRGFEGGQMPLYRRLPKFGFTSMKSAVTAEVRLNELTKVEGNVVTLETLKAANILTKDIQFAKVILAGEVKSAVTVRGLRVTKGAKAAIEAAGGSIEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RTCB_MYCTO
Sequence: MQVVNVATLPGIVRASYAMPDVHWGYGFPIGGVAATDVDNDGVVSPGGVGFDISCGVRLLVGEGLDREELQPRLPAVMDRLDRAIPRGVGTAGVWRLPDRNTLQEVLTGGARFAVEQGHGVALDLERCEDGGVMTGADAAKISDRALQRGLGQIGSLGSGNHFLEVQAVDRVYDPVAAAPMGLAEGTVCVMIHTGSRGLGHQICTDHVRQMEQAMGRYGIAVPDRQLACVPVHSPDGQAYLAAMAAAANYGRANRQLLTEATRRVFADATGTPLDLLYDVSHNLAKIETHPIDGQLRSVCVHRKGATRSLPPHHHELPAELAAVGQPVLIPGTMGTASYVLAGVTGNPAFFSTAHGAGRVLSRHQAARHTSGEAIRASLAKRGIIVRGTSRRDIAEEKPEAYKDVDEVIEASHQSGLARKVARLVPLGCVKG
What is the function of this protein?
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair.  Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends.
What are the official names of this protein?
RNA-splicing ligase RtcB, 3'-phosphate/5'-hydroxy nucleic acid ligase.
What is the protein family that this protein belongs to?
Belongs to the RtcB family.
Protein: HEM1_STACT
Sequence: MHIIAISINHRTADVALREKVAFKADAIRESHLDLFETKSILENVILSTCNRTEVYAVADQIHTGRYYIQRFLARKFGLEVDEIKEMSEVFVGDEAVEHIFRVTAGLDSIVLGETQILGQMRDAFFIAQEEGTTGTIFNHLFKQAITFAKRAHHETDIADNAVSVSYAAVELAKKVFGNLKSKHAVIVGAGEMSELSLLNLLGAGIDNITVVNRTKERAQQLAEKHQTQYADLSNLNELLVNADIVISSTSAQNYVITQEMMNNVLDQRRHEPMVLIDIAVPRDIDPAIELDMNVFSYDIDDLKGLVDANLRERQAAADQIAEQIPAEINEHNDWVNMLGVVPVIRALREKAMHIQQDTMDSIDRKLPDLSERERKVISKHTKSIINQMLKDPIKQAKELSNDKNSSEKLELFQNIFDIEAESEYKKSLAKKERKLSARHILGFE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: LDOX_VITVI
Sequence: MVTSVAPRVESLSSSGIQSIPKEYIRPQEELTSIGNVFEEEKKDEGPQVPTIDLKDIESEDEVVRREIRERCREELKKAAMEWGVMHLVNHGISDDLINRVKVAGETFFNLPMEEKEKYANDQASGKIAGYGSKLANNASGQLEWEDYFFHLIFPEDKRDMTIWPKTPSDYVPATCEYSVKLRSLATKILSVLSLGLGLEEGRLEKEVGGMEELLLQKKINYYPKCPQPELALGVEAHTDVSALTFILHNMVPGLQLFYEGKWVTAKCVPNSIIMHIGDTIEILSNGKYKSILHRGLVNKEKVRISWAVFCEPPKEKIILKAHCQRRCLRLSHHSSHLAPFPNIFSTSSSGRPRRLYSPNEL
What is the function of this protein?
Oxidation of leucoanthocyanidins into anthocyanidins.
What are the official names of this protein?
Leucoanthocyanidin dioxygenase, LDOX, Leucocyanidin oxygenase, Leucoanthocyanidin hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: LRIT1_RAT
Sequence: MWVALGMLWLLALGGPHQAWSFCPSQCSCSLHILSDGSKARTVVCSDPDLTLPPASIPPDTCKLRLERTAIRRVPGETFRPLSRLEQLWLPYNALSELSTLMLRGLRRLRELRLPGNHLVTFPWAALKDTPQLQLLDLQANRLSTLPPEAVHFLENLTFLDLSNNQLMRLPEELLDTWAHLKTGPYLSSRRTRLVLGLQDNPWVCDCRLYDLVHLLDGWASNLIFIEARLRCGSPRSLAGVAFSQLELRKCQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSWRRANGRPLNGTVHQEVSSDGSSWTLLDLPVVSLFDSGDYICQAKNFLGASETLISLIVTEPQTSTEYTGIPGALWARTGEGAEAAAYNNKLVARHVPHVPEPVALATKPSVPSIKEELPLQNFQMDVPGEFSREPSEHQETQMVRSLKVVGDTYHSVSLVWKAPQAGNTTAFSVLYAVFGQRDMRRMTVEAGKTSVTIEGLAPKTKYVACVCVRGLVPTKEQCVIFSTDEVVDAEGTQRLINMVVISVAAIIALPPTLLVCCGALRRRCHKCRAGGSAEASGAYVNLERLGHSEDGSEELSRSSLSEADRLLSARSSLDSQVLGVRGGRRINEYFC
What is the function of this protein?
Possible role in phototransduction.
What are the official names of this protein?
Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1, Leucine-rich repeat-containing protein 21, Photoreceptor-associated LRR superfamily protein, Retina-specific protein PAL.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RECO_HAEIG
Sequence: MQSELQRGFVLHRRPYSETSLLVDLFTEESGRLTVIAKGARAKRSSWKSVLQPFTPLLLRWTGKSTLKTLAKAEPAAITLPLQQIALYSGFYVNELLTRVIESETPNPALFQHYLKCLTGLATETNIEPTLRLFEFQLLQILGYGVDFLHCAGSGEPVDFSMTYRYREEKGFIASLVKDNLTFYGRDLLAFEALDFSDDAVRQAAKRFTRIALKPYLGDKPLKSRELFTQNILLLK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: DAPF_PSEA8
Sequence: MLLRFTKMHGLGNDFMVLDLVSQHAHVQPKHVKLWGDRNTGIGFDQLLIVEAPSSPDVDFRYRIFNADGSEVEQCGNGARCFARFVQDKRLTVKKSIRVETKGGIIELNIRPDGQVTVDMGPPRLAPAEIPFQAEREALSYEIEVNGQRVELAAVSMGNPHGVLRVENVDSAPVHSLGPQLEVHPRFPKKANIGFLQVLDPHHARLRVWERGVGETQACGTGACAAAVAGIRQGWLQSPVQIDLPGGRLHIEWAGPGQPVMMTGPAVRVYEGQVRL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRC8_DROME
Sequence: MSVRTKVLGLVDVMMRVPPVMVIDEILKMDMGMQSWLYPDKDKASGALATPTEAPAVPSGQDPFTSIKELFSHMTTSAQSVLEQSIEKASEAAKTHGMLSSGFNSLMNELSKDQTLADVLSTTTVKFVLCVFAFLSAACIFMLWTRHLVMVYMFLTSLGLTFLSYWSNVSALALTERSPSMVEDLMSLNTTRLLDSGGVVMSLAPHLMAQWFMGMLFAYIHLGPRFEHVQRSMPIIFASPILLAMLPLPAKVVQHLPVVAVFTPIILTKITLMQSAMEASRTVYNGYQYAMNFVSNFGLSALIENEWQRLNVPNVLRVFWTIRLIQGGYALATTESDEPLDLMTATQKLLVDGCETMTAVLGMTGVISMFCHYIGRGFQWYLLTYDDEEKSLGTVSAVLFYILALQTGLTSLSPDKRFIRLCRNLCLLMTALLHFLHNIVSPILMSLSAARNPSRKRHVRALSVCAFLVVLSVSLLYHLWSQQSISTWLLAVTAFSVEVVVKVLVSLATYTLFLLDARRQFFWEKLDDYLYYVRAFGNSVEFCFGILLFINGAWILIFESAQNATGGGIRAIMMCIHAYFNIWCEARAGWSVFMKRRSAVHKISALPEATPAQLQAFDDVCAICYQEMYSAKITRCRHFFHGVCLRKWLYVQDRCPLCHEIMMYTDKADENAPEAEPAPAAQAEQPMRIYPRDDANNAAAQRRSPERAPVEASEQAPATSSSSAAATIGAEAVSAIVESAAAVGEARSLVSVASSSSATHRISASGSSDSSYMTASAQSPPPTATSAAAVATAAASNTTHMFRMSQDQQ
What is the function of this protein?
Plays a role in growth inhibition that is dependent upon COP9 signalosome subunits CSN5 and CSN6.  May modulate signalosome levels or compartmentalization.  Probably functions in the same or a related pathway to VHL during early midline development.
What are the official names of this protein?
Protein TRC8 homolog.
Protein: TUBE_LAMBD
Sequence: MPVPNPTMPVKGAGTTLWVYKGSGDPYANPLSDVDWSRLAKVKDLTPGELTAESYDDSYLDDEDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNEGDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTAATGMTVTPASTSVVKGQSTTLTVAFQPEGVTDKSFRAVSADKTKATVSVSGMTITVNGVAAGKVNIPVVSGNGEFAAVAEITVTAS
What is the function of this protein?
Forms the phage's tail tube composed of 32 hexameric disks.  When it encounters the appropriate initiation complex gpM and gpL, it assembles in hexameric rings that stack on top of each others.  Multimerization ceases when the correct tail length is achieved through a mechanism dependent on tail terminator protein.
What are the official names of this protein?
Tail tube protein, TTP, Gene product V, gpV, Major tail protein V.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: SYI_CALBD
Sequence: MDWSQTLNLPKTDFPMRANLAQREPQFLKFWQENDIFKKMLEKNKNNKKFILHDGPPYANGDIHLGHALNKVLKDIVNKYKSLQGYYTPYIPGWDTHGLPIEQQVIKKLEVNRHEVDPVEFRKKCKEFALSYIDIQRQQFKRLGVFGEWENPYMTLDPKFEARQIRVFGEMAKKGYIYKGLKPVYWCPSCETALAEAEIEYQEDRTYSIYVKFEVIDDKGLFSNLPIGDKKVYIVIWTTTTWTLPGNLAIALNADFDYSLIDIGNEILVVASELVERVMKTNKIEQYKEIARFKGKDLEYVKCKHPFLDRTSLVILGEHVTLEAGTGCVHTAPGHGEEDFEVCQRYNIHVIVPVDNKGYLTKEAGKFAGLFYEDSNKEIAKELEASGHLLGVEKITHQYPHCWRCKNPVIFRATEQWFASVKGFRDQALKAVDDVKWVPEWGRDRIYNMIVDRQDWCISRQRIWGVPIPIFYCKNCRKELITDETIDYIAKIFEKEGSDAWFSKDVKELLPEGVKCPVCGCSEFEKETDIMDVWFDSGSSHAYVLESREDLEWPCDMYLEGNDQYRGWFQSSLLTAVATKGRAPYRIVLTHGFVVDGEGKKMSKSEGNVISPFDIINEFGADILRLWCVSADYTTDMRISKDIIKQLTEIYRKIRNTARFLLGNLYDFNPKTDKVGYENLKEIDKWALQRLYKLIEKVTKAYEEYDYNQVYHLVHNFCVIDMSNLYLDINKDRLYASKSESLDRRSAQTVMYEILIALTILIAPILSFTAEEIWQNIIFKEEDAESVFLTRWPSINEDILRDEALREKWDKIIEIKDIVSKQLEIARNEKLIGSSLDSKVKIFAKCDIKRFIEENKDIIQEVLIVSQLDVEESDSDQIKVEVYKADGSKCERCWKFDTMVGKNEESLNVCPRCYEVVKSK
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REC04_HUMAN
Sequence: MNPSEMQRKAPPRRRRHCNRAPLTHKMNKMVTSEEEMKLPSTKKAEPLTWAQLKKLTQLATKCLENTKVTQTPESMLLAALMIVSMVSAGVTNSSKETATIENGP
What is the function of this protein?
Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the initial genomic transcript.  Rec interacts with a highly structured RNA element (RcRE) present in the viral 3'LTR and recruits the cellular nuclear export machinery.  This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts (By similarity).
What are the official names of this protein?
Endogenous retrovirus group K member 104 Rec protein, HERV-K104 Rec protein, HERV-K_5q13.3 provirus Rec protein.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between the nucleus and the cytoplasm. When in the nucleus, resides in the nucleolus (By similarity).
Protein: DXS_ECO27
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLLDFFIPQGTQEEMRAELGLDATGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: ZN229_HUMAN
Sequence: METLTSRHEKRALHSQASAISQDREEKIMSQEPLSFKDVAVVFTEEELELLDSTQRQLYQDVMQENFRNLLSVGERNPLGDKNGKDTEYIQDEELRFFSHKELSSCKIWEEVAGELPGSQDCRVNLQGKDFQFSEDAAPHQGWEGASTPCFPIENFLDSLQGDGLIGLENQQFPAWRAIRPIPIQGSWAKAFVNQLGDVQERCKNLDTEDTVYKCNWDDDSFCWISCHVDHRFPEIDKPCGCNKCRKDCIKNSVLHRINPGENGLKSNEYRNGFRDDADLPPHPRVPLKEKLCQYDEFSEGLRHSAHLNRHQRVPTGEKSVKSLERGRGVRQNTHIRNHPRAPVGDMPYRCDVCGKGFRYKSVLLIHQGVHTGRRPYKCEECGKAFGRSSNLLVHQRVHTGEKPYKCSECGKGFSYSSVLQVHQRLHTGEKPYTCSECGKGFCAKSALHKHQHIHPGEKPYSCGECGKGFSCSSHLSSHQKTHTGERPYQCDKCGKGFSHNSYLQAHQRVHMGQHLYKCNVCGKSFSYSSGLLMHQRLHTGEKPYKCECGKSFGRSSDLHIHQRVHTGEKPYKCSECGKGFRRNSDLHSHQRVHTGERPYVCDVCGKGFIYSSDLLIHQRVHTGEKPYKCAECGKGFSYSSGLLIHQRVHTGEKPYRCQECGKGFRCTSSLHKHQRVHTGKKPYTCDQCGKGFSYGSNLRTHQRLHTGEKPYTCCECGKGFRYGSGLLSHKRVHTGEKPYRCHVCGKGYSQSSHLQGHQRVHTGEKPYKCEECGKGFGRNSCLHVHQRVHTGEKPYTCGVCGKGFSYTSGLRNHQRVHLGENPYK
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 229.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MINC_SHESW
Sequence: MSKPSLELKGASFTLSVLHINSSDLNAVMAELDSKLAQAPQFFLGAPLVVNLSAIQHNDFNLHGLKELLLSRQLVIVGITGATTVLSKQAKDLGLAIVKAGKQSTTPPPAPRQTKIVKQNIRSGQQVYAKNGDLIIFGAVGNGAEVIADGSIHIYGALRGKAMAGAAGDPTAVIIAHSLEAELVSIAGQYWLAENLQQHSSDKSGCIRLNGESLMVESLPL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ATPA_STRPS
Sequence: MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPO1C_SULIN
Sequence: MIDEKDKSYLEEKVKQASNILPQKIVEDLKNLISNKEVLVTRDEIDKIFDLAIKEYSEGLIAPGEAIGIVAAQSVGEPGTQMTLRTFHFAGIRELNVTLGLPRLIEIVDAKKVPSTPMMTIYLTDEYKHDKEKALEVARKLEYTKIENVVSSTSIDIASMSIILQLDNEMLKDKGVTVDDVKKAINRLKLGEFVIDESEGNTLNISFANIDSIAALFKLRDKILNTKIKGIKGIKRAIVQKKGDEYIILTDGSNLSGVLSVKGVDIAKVETNNIREIEEVFGIEAAREIIIREISKVLAEQGLDVDMRHILLVADVMTRTGVVRQIGRHGVTGEKNSVLARAAFEVTVKHLLDAAARGDVEEFKGVVENIIIGHPIKLGTGMVELTMRPILR
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms part of the jaw domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1C, DNA-directed RNA polymerase subunit A''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.