PharMolix/UniProtQA huggingface dataset:
Protein: GRID2_MOUSE
Sequence: MEVFPLLLFLSFCWSRTWDLATADSIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEACELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLSVRPPVYLNEVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENNINKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSSLCDPKDPFAQNMEISNLYIYDTVLLLANAFHKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVNGLTGDLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLENNMRGVVLRVVTVLEEPFVMVSENVLGKPKKYQGFSIDVLDALSNYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYSVGVLLRRAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIVISSYTANLAAFLTITRIESSIQSLQDLSKQTDIPYGTVLDSAVYQHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQAGIQKVKYGNYAFVWDAAVLEYVAINDPDCSFYTVGNTVADRGYGIALQHGSPYRDVFSQRILELQQSGDMDILKHKWWPKNGQCDLYSSVDAKQKGGALDIKSLAGVFCILAAGIVLSCLIAVLETWWSRRKGSRVPSKEDDKEIDLEHLHRRVNSLCTDDDSPHKQFSTSSIDLTPLDIDTLPTRQALEQISDFRNTHITTTTFIPEQIQTLSRTLSAKAASGFAFGSVPEHRTGPFRHRAPNGGFFRSPIKTMSSIPYQPTPTLGLNLGNDPDRGTSI
What is the function of this protein?
Receptor for glutamate.  L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.  The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists.  Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex.
What are the official names of this protein?
Glutamate receptor ionotropic, delta-2, GluD2, GluR delta-2 subunit.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRID2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi- pass membrane protein.
Protein: LPXB_XYLFM
Sequence: MIQAPRIALIAGEASGDHLGAGLIQQLRLHFPTAEFIGIGGDMMRSAGCQTWFDTTELAVMGLTEVLRHLPRLLKIRREFCKRALAWHPDVLIGIDAPDFNLTVERWFKQRHIRTVHYVSPSIWAWREKRAAKIGASVDRVLCLFPMEPPIYARYGIDARFVGHPMADEIPYQTDRATARTALGLPLLSPVLAVLPGSRHSEISQLGNTFLEAAGQLSEHLPGLHVVIPAANTQCKPLLAEQLSRSTLPVMHSHLLDSSARTAMLAADVVLVASGTATLEAMLLKRPMVVAYKVAPLTYRIVKTLKLLKINRFALPNILAGEDLAPELIQKDCTAPALCAALLHWFKHPQKVTALQNRYLQLHTQLRRNASTRAAEAIAELLQQR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: RL17_COXBU
Sequence: MHHRKSGRHLNRTSAHRKAMLRNMAVSLFQHELIKTTLPKAKELRRVVEPLITLAKEDTVANRRLAFNRLRDDAIVAKLFKEIAPRHKERPGGYCRVLKYGFRNGDSAPMAIVELVDREESESSED
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RS7_MYCGE
Sequence: MRKNRALKRTVLPDPVFNNTLVTRIINVIMKDGKKGLAQRILYGAFEIIEKRTNQQPLTVFEKAVDNVMPRLELKVRRIAGSNYQVPTEVPPDRRIALALRWIVIFANKRNEKTMLERVANEIIDAFNNTGASVKKKDDTHKMAEANKAFAHMRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: HIS5_BUCBP
Sequence: MSIVIINTGCANLSSLKYAIQRLGYNVIITSNHKNILNAKKVFLPGVGTAFSAMKMLNQFKLKDVLYKYQQPVLGICLGMQLLCSFSSENNGIKMLDIIHAPVNILKSNKFPLPHNGWNNVSVCDENPLFIGIKNNSKFYFLHSYALYENDYMIAKTFYNVYFSAAVRKENFFGVQFHPEKSGLVGLQLLKNFLEI
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_ACTSZ
Sequence: MARYFRRRKFCRFTAENVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLALLPYTDNHQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ARGJ_ACIAD
Sequence: MAVGDVTMPHMHVVNGVKIGSTEAYVRYPNRRDLVVFKFVEGSHVAGVFTQSAFAAAPVLVSKKHLAESAIRYLIINTGNANAATGQTGVINAQKTCTKLAELAGVESSQVLPFSTGVIGEQLPIERLLDGIQPALQDLKDDAWTEAAFGIMTTDTTPKGASEQFELDGVVYTMTGISKGAGMIRPNMATMLSFVATDAPISQSLVQTLLKTTVEQSFNRITIDGDTSTNDSCIFVATGQAGGVEISSEQDPRYSKILEILQRIMNRLAQLIVRDGEGATKFITVAVEGGENTQECCDVAYSIAHSPLIKTAVFASDPNWGRIVMAIGKAGVPQLDVSKVQVWLDDVQICRDGGAAADYTEEQGARVMAQAEMTIRVDLGRGTAKDTVYTCDLSYDYVKINADYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSUB2_BURL3
Sequence: MSPPPSAHTAASTATPLLDLRITRKLYGDRTILADVPLQVARGEIVCVVGPSGCGKSTLLRIVAGLDTDFRGSVKLGGIALDGPSPRAGVIFQEPRLLPWLSIADNVGFAAGPRGGREPSVARLLDEVGLAGVARQLPATLSGGMAQRAAIARGLFGEPDLLLLDEPFSAVDAITRMRLQTLLLDVVERHRTAAIVVTHDLDEALYLGDRVLMLAPNPGRIDDEIHVEVARPRDRRDPTLAVLRARLLDAFQQLQDRADETKRRTLDLQGAEA
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CXCL6_HUMAN
Sequence: MSLPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN
What is the function of this protein?
Chemotactic for neutrophil granulocytes.  Signals through binding and activation of its receptors (CXCR1 and CXCR2).  In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).
What are the official names of this protein?
C-X-C motif chemokine 6, Chemokine alpha 3, CKA-3, Granulocyte chemotactic protein 2, GCP-2, Small-inducible cytokine B6.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YYAJ_BACSU
Sequence: MNTIFKQKNTHPFSNAANRLDRLPISRVHFQVLTALGIVYFFDLADLFTLSNVAPALIEHWGIPLSTIANVTAASFLGMFLGASLGGRLSDRIGRKKALNLFVFVFSIASLCNAAAWDIPSLMTFRFLTGFGVAAAMVITNSYLAEFFPSSVRGKYISFCAMIGLIGVPITNIVSAFVIPLGSWGWRLVFVWGAVGLIYFFFIHRLEESPRWHENRGEYAKADAILTRIEEQVEKEKGPLPAASQPKVSETVKQNAGYAGLLKGRNLKITIVLSAVWIFETFGFYGFASWVPSLLKSNGVTMENTLWYNVLHSVGAPLGALLGSMISERFQRKWILAASAFLTAIAGLLYGMTFIPIMIIVFGFIVNITERVFTSNLYAYTSEPYPTEYRSSGSGLAYGLGRFSNIFGSLLVGFIAVQLGYISVFLFIGGCWLACSLLLIFFGPNTNAKQI
What are the official names of this protein?
Putative metabolite transport protein YyaJ.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DCUP_MYCTA
Sequence: MSTRRDLPQSPYLAAVTGRKPSRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPDVACEITLQPIRRYDVDAAILFSDIVVPLRAAGVDLDIVADVGPVIADPVRTAADVAAMKPLDPQAIQPVLVAASLLVAELGDVPLIGFAGAPFTLASYLVEGGPSRHHAHVKAMMLAEPASWHALMAKLTDLTIAFLVGQIDAGVDAIQVFDSWAGALSPIDYRQYVLPHSARVFAALGEHGVPMTHFGVGTAELLGAMSEAVTAGERPGRGAVVGVDWRTPLTDAAARVVPGTALQGNLDPAVVLAGWPAVERAARAVVDDGRRAVDAGAAGHIFNLGHGVLPESDPAVLADLVSLVHSL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF1_NICPA
Sequence: MARSLCFMAFAVLAMMLFVAYEVQAKSTCKAESNTFPGLCITKPPCRKACLSEKFTDGKCSKILRRCICYKPCVFDGKMIQTGAENLAEEAETLAAALLEEEMMDN
What are the official names of this protein?
Defensin-like protein 1, Gamma-thionin 1.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted. Vacuole.
Protein: HIS5_HAEIN
Sequence: MINITIIDTGCANLSSVKFAFDRLGYNTEITFDLNKIKSADKLILPGVGTANAAMYNLQERQLIETIQNLTQPVLGICLGMQLMTEFSEEGNVPTLNLISGKTNRIPDTGLPLPQMGWNRVQFVKNCPLFDGIVQNSHFYFVHSYAVSPNEHSVAISNYGVNFSAAIAKENFYGVQFHPERSGKNGALLLKNFVEKVPF
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR.  The resulting ammonia molecule is channeled to the active site of HisF (By similarity).
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisH, IGP synthase glutaminase subunit, IGP synthase subunit HisH, ImGP synthase subunit HisH, IGPS subunit HisH.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5C_DRANE
Sequence: MEHTYQYSWIIPFIPLPVPILLGIGLLLFPTVTKSLRRMWTFLSIFLLSIVMIFSVYLSIQQIFLSCIHQNVWSWTINNEFSFEFGYFIDPLTSIMLILITTVGILVLIYSDNYMAHDQGYLRFFAYLGFFTTSMLGLVTSSNLIQVYFFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGLYWITGSFEFQDLFEIVNNLILNNRVNLLFLTLCAFLLFVGPIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFIVIPSIMYIISLIGIITVLLGATLALAQKDIKRGLAYSTMSQLGYMMLALGMGSYRPALFHLITHAYSKALLFLGSGSIIHSMEAIVGYSPDKSQNMILMGGLTKHVPITKTAFLIGTLSLCGIPPLAWFWSKDEILNDSLLFSPIFAIIACSTAGLTAFYMFRIYLLTFEGHLNTYFINYSGKKSSSFYSISLWGKAEEKKLNRNFELVPLLTMNNTKRVSFFGKKTYKISNNVTNQTFITVENFGLNTRTFYYPQESDNTILFPMLVLLLFTLFVGTIGIPFNQEGLDFDILSKLLTPSINLLHKNSQNFVDWYEFLQNATFSVSIALFGIFIAYCLYKPFYSSLLNLTLLNSFKTWSSKRIRWEKLINLVYNWSYNRGYIDAFFKTSLTENIRRLAKQMNFFDKRIIDGITNGVGITSFFVGEVTKYISGSRISFYLFLYLSYVFIFLMILFFFYFEKF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 5, chloroplastic, NAD(P)H dehydrogenase subunit 5, NADH-plastoquinone oxidoreductase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CWC25_YARLI
Sequence: MPGDLNLKKSWHPGLHKNQAVVHAKEQEALEERRRIQERQKEIKQQRERDELQKLQEMATGKKRVQKVEWMYQDPTAVGSQQAFNEKKVDANSTDDYLLGKRRIDSIVKQKGDLEAFDDSLDRFQPKTDKSESAGIVHKVKDDPMVAVRQKGRELGYTDEANESERRSRRERSRSRERERRRPRRKREDSRDRRNRRDMEREGERRRRRRDGERTRRRERNRDPSPSVSDDDRGYRQSSREERDRKSSREEGGRSRSRDRYRNRSRERYRDRSREERSRDRSRERLRSRRDRDRDRDRDRDRDRDRDNVQSSGRSSGRSSVRSSARSERSLRDRSRSRDPDRDRDYRSRSRERDSGGGQGSDLSDEVGNGRSVLDERSTDMNASDGNSSHGYRADNEFSPSRSPVTRSHRDKRNSYRPEYKDEDDKRFAQRKDKEKEMNALPKGLQQMRAKLLASKKTTTVSGTSQTPTSAPSGSQRTPSAASGSSPTGKAATDAKLSDRLARLKAMQEDAKALEEERDERLASKTKHEEAERLRDALLRQKSAHLGRSEFAREEERKDLK
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC25.
What is the protein family that this protein belongs to?
Belongs to the CWC25 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNMA2_ALIB4
Sequence: MNKNKKIVVGMSGGVDSSVTALLLKQQGYDVVGLFMRNWEYGIKGSQCPNRIEFEDAKKVGALIGIEVRGKDFVKEYRDRVFDVFLEGLKQGLTPNPDILCNKEIKFNVFLNEAKSMGADMIATGHYAKIAKYKDHFVLDTPKDNTKDQSYFLHALSSEQLSHAMFPLGDLTKKEVREIARAHNLPVSDKKDSTGICFIGNQKFDEFITQHLQAIPGDILDENGKVIGKHKGLVCYTLGQRKGIGLGGIKGNESENNTHKPWFVASKDVVNNTLTIVQDTNHPLLMSKTVEASHMHWVLEEAPKVGDKLMAQVRYRQQKQACTVVEANEEKVVVEFDNPQRAVTLGQSLVLYSGDYCLGGGFISFYK
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 2.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NCAP_PI1HC
Sequence: MAGLLSTFDTFSSRRSESINKSGGGAIIPGQRSTVSVFILGPSVTDDADKLLIATTFLAHSLDTDKQHSQRGGFLVSLLAMAYSSPELYLTTNGVNADVKYVIYNIERDPKRTKTDGFIVKTRDMEYERTTEWLFGPMINKNPLFQGQRENADLEALLQTYGYPACLGAIIVQVWIVLVKAITSSSGLRKGFFNRLEAFRQDGTVKSALVFTGDTVEGIGAVMRSQQSLVSLMVETLVTMNTSRSDLTTLEKNIQIVGNYIRESGLASFMNTIKYGVETKMAALTLSNLRPDINKLRSLVDIYLSKGARAPFTCILRDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGRTYLDMEMFLLGQAVAKDADSKISSALEEELGVTDTAKERLRHHLTNLSGGDGAYHKPTGGGAIEVAIDHTDITFGAEDTADRDNKNWTNNSNERWMNHSINNHTITISGAEELEEETNDEDITDIENKIARRLADRKQRLSQANNRQDASSDADHENDDDATAAAGIGGI
What is the function of this protein?
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: FADA_ALIFM
Sequence: MKNVVIVDCIRTPMGRSKNGVFRYTRAEDLSAHLMKGLLKRNPSVDPNDIEDIYWGCVQQTLEQGFNIARNSALLAGLPQSIAATTVNRLCGSSMQALHDASRAIMVGDAEICIIGGVEHMGHVPMNHGVDFHSGLSKSVAKASGMMGLTAEMLGKMHGISREQQDAFALASHQKAHKATIEGYFDSEILPIEGHDENGVLTLVTHDEVIRPETTLEGLAALRPAFDPANGTVTAGSSSALSDGASAMLVMSEEKANELGLPIRAKVRSMAVSGCDPSIMGYGPVPATKKALKRAGLSLDDIELFELNEAFAAQSLPCIKDLGLLDVMDEKVNLNGGAIALGHPLGCSGSRIATTLINNMERTGAKLGVATMCIGLGQGIATVFERP
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPB_RHIME
Sequence: MAKAATPKETAAAKKPAAPKKAASAKTVVAATGAVGRVTQVIGAVVDVAFEEGQLPQILNALETDNNGNRLVLEVAQHLGENSVRTIAMDSTEGLVRGQKVADTGGPIAVPVGKETLGRIMNVIGEPVDEAGPLKTSARRAIHQEAPAYVDQSTEAQILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVNKHGGGEGSKAALVYGQMNEPPGARARVALTGLTVAEQFRDEGQDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGQMQERITTTTKGSITSVQAIYVPADDLTDPAPATSFAHLDATTVLSRSIAEKGIYPAVDPLDSTSRMLDPMIVGEEHYEVSRKVQSTLQRYKALQDIIAILGMDELSEEDKIAVARARKIERFLSQPFFVAEVFTGSPGKLVALEDTIKGFKGLVNGEYDHLPEAAFYMVGSIEEAVEKAKKLAAEAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1781_STRPM
Sequence: MGFTDETVRFKLDDGDKRQISETLTAVYHSLDEKGYNPINQIVGYVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDVK
What are the official names of this protein?
UPF0297 protein M28_Spy1781.
What is the protein family that this protein belongs to?
Belongs to the UPF0297 family.
Protein: ERA_LACLA
Sequence: MTNNKFKSGFVAILGRPNVGKSTFMNHVMGQKIAIMSDKPQTTRNKIQGIYTTENEQIVFIDTPGIHKPHNALGDFMVQSAYSTLRECDVVLFMVAADEPRSTGENMIIERLKKAEVPVILVVNKIDKIHPDRLFEIVADYTSQMEFSEVVPISAKQGNNTERLIDTLSEKLDEGPQYFPEDQITDHPERFLVSEMIREKILLLTREEVPHSIAVTTDQMTRDEETGKIHIMATIIVERKSQKGIILGKGGDMIRKIGKMARRDIEIMLGDKVYLETWVKIKNDWRDRKMDLADFGYNRDDYM
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: ASCL1_HUMAN
Sequence: MESSAKMESGGAGQQPQPQPQQPFLPPAACFFATAAAAAAAAAAAAAQSAQQQQQQQQQQQQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNERERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDAVSAAFQAGVLSPTISPNYSNDLNSMAGSPVSSYSSDEGSYDPLSPEEQELLDFTNWF
What is the function of this protein?
Transcription factor that plays a key role in neuronal differentiation: acts as a pioneer transcription factor, accessing closed chromatin to allow other factors to bind and activate neural pathways.  Directly binds the E box motif (5'-CANNTG-3') on promoters and promotes transcription of neuronal genes.  The combination of three transcription factors, ASCL1, POU3F2/BRN2 and MYT1L, is sufficient to reprogram fibroblasts and other somatic cells into induced neuronal (iN) cells in vitro.  Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS.  Essential for the generation of olfactory and autonomic neurons.  Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation.  Involved in the regulation of neuroendocrine cell development in the glandular stomach (By similarity).
What are the official names of this protein?
Achaete-scute homolog 1, ASH-1, hASH1, Class A basic helix-loop-helix protein 46, bHLHa46.
What are the subcellular locations of this protein?
Nucleus.
Protein: YC097_YEAST
Sequence: MLKYVVTDIGKMCLYIWPYRVWSWRRLFIFRVLNVVSIAILFETPHRLALVLNVCLYTHISMCLYNCYCLYNVVTFSLNLILISMTFI
What are the official names of this protein?
Putative uncharacterized protein YCR097W-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GASA3_ARATH
Sequence: MAIFRSTLVLLLILFCLTTFELHVHAAEDSQVGEGVVKIDCGGRCKGRCSKSSRPNLCLRACNSCCYRCNCVPPGTAGNHHLCPCYASITTRGGRLKCP
What is the function of this protein?
Gibberellin-regulated protein that may function in hormonal controlled steps of development such as seed germination, flowering and seed maturation.
What are the official names of this protein?
Gibberellin-regulated protein 3, GAST1 protein homolog 3.
What is the protein family that this protein belongs to?
Belongs to the GASA family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSA_GEOMG
Sequence: MNTSHSKELFAKAQEIIPGGVNSPVRAFKSVGAEPVFIKKASGSTIIDADDNAYIDYVGSWGPMILGHCHPRIVASVQRATENGSSFGAPTELEITLAEMVVAAVPSIEMVRMVSSGTEATMSAIRLARGYTGRDKIIKFSGCYHGHADSLLVKAGSGAATFGVPDSPGVPRDFAQHTLTATFNDLESVEELICAHSREVACIIVEPIAGNMGTVPPRAGFLEGLREICTNEGIILIFDEVMTGFRVAYGGAQERYGITPDMTTLGKIIGGGLPVGAFGGKREIMQQLSPSGGVYQAGTLSGNPLAMTAGIETLKLLQEDGFYGRLEEKSRALAEGIADAARRAGYPIYSTRVGSMFCAFFTNGEVHDWTSAAMCDTKSFATFFRSMLEEGIYLAPSQFETAFVSIAHSSEDIEKTIAAAFSCFKKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMI12_ORYSJ
Sequence: MRMSKALAAVVAISVSLSAAAMGVDATVESTCSDAAASDKRVHLAMCLSQLGHHRDADAWGLAKAATLVGVDKADLAADDIKELEAGASTAGIKPALAECAKQYRGVGFAFASAHDVINNRAYDVGEKKLDEALSLTQKCNAAFAKIGVPLQQPLAQLTADTIQIAIIAKAITCLVNVNNNPALVAAAAAAAAAKAPQQSQYP
What is the function of this protein?
Pectin methylesterase (PME) inhibitor that inhibits PME in vitro.
What are the official names of this protein?
Pectinesterase inhibitor 12, Pectin methylesterase inhibitor 12, OsPMEI12.
What is the protein family that this protein belongs to?
Belongs to the PMEI family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: IHFA_MANSM
Sequence: MTLTKVELADNLIEKHGLNKSEAKALVEDFFEEIRVALEKGNDVKLSGFGNFELREKASRPGRNPKTGESVPVSARRVVVFKPGQKLRARVEKTKPKS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: TGT_DICNV
Sequence: MNYECMTQDGRARRGRIIFDNGQIVQTPVFMPVGTQATVKGLSPEELDALGAEIILGNTFHLMLRPGAEIIQAHGGLHQFMHWQKPILTDSGGFQVFSLAKIRKLTEEGARFRSPIDGREVFLTPEKSIAVQHALNSNIIMQLDECTPYPATYDEAANSMRMSLRWARRSQQAHGDHANHLFGIVQGGIYPDLRQESAQALVELDLPGYAIGGLAVGEPKDAREATLDAVLPFVPKNKPRYLMGVGKPADLVEGVRRGIDMFDCVMPSRNARNAYLFTRFGILKLRNSRYKEDLRPIDETCNCYTCQRYSRSYLHHLDKCNEILGARLNTIHNLYYYVHLMHEMRRAIEEHRFDDFARAFYAEQECGND
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.