PharMolix/UniProtQA huggingface dataset:
Protein: RPO1N_HALS3
Sequence: MSAGQAPKEIGEISFGLMDPEEYRDMSATKVITADTYDDDGFPIDMGLMDPRLGVIDPGLECKTCGQRSGGCNGHFGHIELAAPVIHVGFSKLIRRLLRGTCRECASLLLTEEEKDEYRENLDRTRSLRQDVSDVMTAAIREARKKDHCPHCGEVQYDVKHEKPTTYYEVQQVLASDYSERIAASMQPDEDEDDAGVSPQELAEQTDIDISRINEILSGEFRPRREDREAIETAIGADLTTEDMNKLMPSDIRDWFEDIPGEDLEALGVNSDRSRPEWMILTVLPVPPVTARPSITLDNGQRSEDDLTHKLVDIIRINQRFMENREAGAPQLIIEDLWELLQYHVTTFMDNEISGTPPARHRSGRPLKTLSQRLKGKEGRFRGSLSGKRVNFSARTVISPDPTLSLNEVGVPDRVATEMTQTMVVNEQNLERARRYVRNGPEGHPGANYVTRPDGRRVRVTEKVCEELAERVEPGWEVQRHLIDGDIIIFNRQPSLHRMSIMAHEVVVMPYKTFRLNTVVCPPYNADFDGDEMNMHALQNEEARAEARVLMRVQEQILSPRFGENIIGAIQDHISGTYLLTNDNPRFNETQASDLLRQTRIDELPAAAGTDEDGDQYWTGHQIFSELLPDDLSLEFTGTTGDTVVIEDGQLLEGTIADDEVGEYGSEIVDTITKVHGNTRARIFINEVASLAMRSIMHFGFSIGIDDETVSTEARERIDEAIQSAYDRVQELIETYENGDLESLPGRTVDETLEMKIMQTLGKARDSAGDVAEENFDEDNPAVVMANSGARGSMLNLTQMAGCVGQQAVRGERINRGYEDRTLSHFAPNDLSSEAHGFVENSYTSGLTPKEFFFHAMGGREGLVDTAVRTSKSGYLQRRLINALSELETQYDGTVRDTSDTIVQFEFGEDGTSPVQVSSNEEVDIDVEHVADRILNSEFDSDTQKAEFLEVEEPPTNLSEHGAAWEVESDD
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Forms the clamp head domain.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo1N, DNA-directed RNA polymerase subunit A'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOL7_ARATH
Sequence: MSLIIVFFFFSLLLTSNGQFFDESKNYEGSSDLVDLQYHLGPVISSPVTSLYIIWYGRWNPTHQSIIRDFLYSVSAPAPAQYPSVSNWWKTVRLYRDQTGSNITDTLVLSGEFHDSTYSHGSHLTRFSVQSVIRTALTSKLPLNAVNGLYLVLTSDDVEMQEFCRAICGFHYFTFPSVVGATVPYAWVGNSERQCPEMCAYPFAQPKPFPGSGFVAREKMKPPNGEVGIDGMISVIAHELAEVSSNPMLNGWYGGEDATAPTEIADLCLGVYGSGGGGGYMGSVYKDRWRNVYNVKGVKGRKYLIQWVWDLNRNRCFGPNAMN
What is the function of this protein?
May play a role in a brassinosteroid-dependent regulation of growth and development.
What are the official names of this protein?
Protein EXORDIUM-like 7.
What is the protein family that this protein belongs to?
Belongs to the EXORDIUM family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, apoplast.
Protein: RBSD_PSEP1
Sequence: MKKTPLLNVALSRVIAGMGHGDILVIGDAGLPVPPGVELIDLAITPGLPDFASVLRVVLSELQVERHVLAEEMQKVVPPALVEIERLKGKLGKREWLTHEDFKVLSRSARAVVRTGECQPYSNIALISGVTF
What is the function of this protein?
Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
What are the official names of this protein?
D-ribose pyranase.
What is the protein family that this protein belongs to?
Belongs to the RbsD / FucU family. RbsD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_STRT1
Sequence: MHVIAVDAMGGDNAPQAIVEGVNQALAEFKDIEIQLYGDEAKIKNYLIANERVSIVHTDEKINSDDEPVKAIRKKKKASMVLGAQAVKEKAADAVISAGNTGALLAAGLFVVGRIKGVERPGLMSTMPSFTGQPFDMLDLGANAENTANHLHQYAILGSFYAKNVRGIATPRVGLLNNGTEKTKGDSLRKEAFELLSQEASINFIGNVEAREIMSGAADVVVADGFTGNAVLKAIEGTGLGTMKTLKSAIMNGGLKAKLGAFLLKDRLKGMKETMDYSSAGGAVLFGLKAPVVKCHGSSDAKAVYYTIKQVRKMLDTKVVEQLVDAFDPKEEVN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: THIC_ECO7I
Sequence: MSATKLTRREQRTQAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQFEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGLLTPKRAKTGRRVTQLHYARQGIITPEMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGSVQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYHDETLPQESGKVAHFCSMCGPKFCSMRISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: NU6M_PELSU
Sequence: MYVSMLFGFSYVFWLIGVSSNISVYYGVVSLVCTAGTGCVVLAWKGGSFLALVLFLIYLGGMLVIFAYSITLVMEPFPEVMGDWVGVMHAGKYVVLAVVFVLVGWGWWGVGECGDGVVDAGGLSIVRVDSSGLSLLYAIGGGALMMAMFGLFLTFFIVLVLVQGLFRVACPTI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: GUAC_LYSSC
Sequence: MDNVFDYEDIQLIPAKCIVESRSECDTSVTLGGHTFKLPVVPANMQTIIDETLAKKLAENGYFYIMHRFQPEARVNFIQDMHGSGLIASISVGVKEEEYAFIEELAATNLVPEFITIDIAHGHSNAVIRMIQHIKKHLPNSFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAATKPIIADGGIRTHGDIAKSVRFGASMVMIGSLFAGHEESPGQTIEVEGKKVKEYFGSASEFQKGERKNVEGKKMFVEHKGSIKDTLIEMQQDLQSSISYAGGTKLDAIRNVDYVIVKNSIFNGDKVY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: COX3_LOCMI
Sequence: MLTNNNNHPFHMVDYSPWPLTGAIGAMILTSGMTKWFHTFNMNLLMIGMTVIVLTMIQWWRDVVREGTFQGLHTKLVSKGLRWGMILFIASEVLFFASFFWAFFNSSLAPTIELGMKWPPMGIQPFNPIQIPLLNTAILLASGVTITWAHHSIMECNHSQALQGLFFTVMLGFYFTLLQMYEYWEAPFTIADAVYGSTFFVATGFHGLHVIIGTTFLLTCLIRHMMNQFSSNHHFGFEAAAWYWHFVDVVWLFLYLSIYWWGS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MK12_DANRE
Sequence: MTARSRPGYFRQEINKTIWEVPDRYKDLKQVGTGAYGTVCYALDRRTGAKVAIKKLHRPFQSDLFAKRAYRELRLLKHMKHDNVIGLVDVFTADLSLDRFHDFYLVMPFMGTDLGKLMKMERLSEERVQYLVYQMLKGLKYIHAAGIIHRDLKPGNLAINEECELKILDFGLARQTDSEMTGYVVTRWYRAPEVILSWMHYTQTVDIWSVGCIMAEMLLGKPLFKGHDHLDQLMEIMKVTGTPSKEFTAKLQSEDARNYVTKLPRFRKKDLRILLPNVNPQAIKVLDGMLLLDPESRITAAEALAFPFFSEFREPEEETEAPPYDHSLDEADQSLEQWKRLTFTEILTFQPAPAVAESKETAL
What is the function of this protein?
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway.  MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors.  Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each.  Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets (By similarity).
What are the official names of this protein?
Mitogen-activated protein kinase 12, MAP kinase 12, MAPK 12, Stress-activated protein kinase 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y010_SIFVH
Sequence: MNNFSYFSTIFSIALMSSNAFAGNDTLLVGFCPCIEINTLTLFLSSLYAIKPSDSCSPSYTSNLLNLFCDFVNSSTHLSISVFSSSVLSCFTSCFVIYFYPFFVFDSASYCVFNSSSREGCTSVTIGWG
What are the official names of this protein?
Putative transmembrane protein 10.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: GLMM_HAHCH
Sequence: MSKEYFGTDGIRGRVGEGPITPEFMLKLGWAAGRVFRQEGRRNRVLIGKDTRISGYIFESALESGLAAAGVDVAMLGPMPTPAIAYLTRTFRACAGIVISASHNPFNDNGVKFFSAEGTKLPDSTEEQIEHFIRQPMEIVPSSQLGKAARFEDAKGRYIEFCKSTVPFHMSFAGMRVVLDCAQGATYQVAPSVFKELGAKVETIGVTPDGLNINHEIGSTHPDQLAAKVVEAGADLGIAFDGDGDRVVMVDHKGEIVDGDEILYIIARDKMRKGRLKGGVVGTLMTNFGAELAFGELGIPFERANVGDRYVMEALLRNDWCLGGEGSGHIVCLDRTTTGDGIISSLQVLAALSDLGITLHEAKKGMSKLPQHMINVRVSQKVDIKGHTTIQSAVANAEKQFAGKGRVLLRSSGTEPVIRVMAEGEDEAKVRSIVAELAKIVEGSV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: KRA55_MOUSE
Sequence: MTCCGCSGGCGSSCGGCGCSGGCGSSCGGCGSSCCCKPVCCCKPVCCCVPACSCSSCGGCKGGCGSCGGCKGSCGSCGGCKGGCGSCGGCGSCGGCKPSCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCSSGCGSSCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCKPCCCQSSCCAPVCCQCKI
What is the function of this protein?
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins.  The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
What are the official names of this protein?
Keratin-associated protein 5-5.
What is the protein family that this protein belongs to?
Belongs to the KRTAP type 5 family.
Protein: PILR1_THUPL
Sequence: MDKKSRVLIVGGTGYIGKRIVNASISLGHPTYVLFRPEVVSNIDKVQMLLYFKQLGAKLIEASLDDHQRLVDALKQVDVVISALAGGVLSHHILEQLKLVEAIKEAGNIKRFLPSEFGMDPDIMEHALQPGSITFIDKRKVRRAIEAASIPYTYVSSNMFAGYFAGSLAQLDGHMMPPRDKVLIYGDGNVKGIWVDEDDVGTYTIKSIDDPQTLNKTMYIRPPMNILSQKEVIQIWERLSEQNLDKIYISSQDFLADMKDKSYEEKIVRCHLYQIFFRGDLYNFEIGPNAIEATKLYPEVKYVTMDSYLERYV
What is the function of this protein?
Reductase involved in lignan biosynthesis.  Catalyzes the enantioselective sequential conversion of (-)-pinoresinol into (-)-lariciresinol and of (-)-lariciresinol into (+)-secoisolariciresinol.  Can also convert with a lower efficiency (+)-pinoresinol into (+)-lariciresinol, but not (+)-lariciresinol into (-)-secoisolariciresinol.  Abstracts the 4R-hydride from the NADPH cofactor during catalysis.
What are the official names of this protein?
Bifunctional pinoresinol-lariciresinol reductase 1, PLR-Tp1, (+)-pinoresinol reductase, (-)-lariciresinol reductase, (-)-pinoresinol reductase.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: RAVA_ECOLC
Sequence: MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFLLGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTSGYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEADSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKEIGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVDLILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKTALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERNALEQWLSKGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQLEELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVSAQIRQAQQC
What is the function of this protein?
Functions as an ATPase.  May play a role in metal insertion (metal-chelatase) or as a chaperone.
What are the official names of this protein?
ATPase RavA, Regulatory ATPase variant A.
What is the protein family that this protein belongs to?
Belongs to the RavA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA2_BACC1
Sequence: MEITFQKVEHRYQHKTPFERRALYDVDVSFPSGGYYAIIGHTGSGKSTMIQHLNGLLQPTNGTVQIGEHFISAGKKEKKLKPLRKKVGVVFQFPEHQLFEETVEKDICFGPTNFGVSVEEAKQKAREAIELVGLEPELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGQNELMEMFYKLHKEKGLTVILVTHNMEDAAKYAEQIVVMHKGTVFLQGSAEEVFSHADELEKIGVDLPMSLKYKRAIEEKFGISIPKATLSLEDLTHEVVQVLRKGGHESCSS
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA2, ECF transporter A component EcfA2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DXR_LISMC
Sequence: MKKIILLGATGSIGTQTLAIIRENPEKFQIVALSFGRNMERGRAIIKEFKPKMVAVWHTRDRVILEAEFPNVKFFNGLEGLREVATYLDGDVLLNAVMGSVGLLPTLDAIEAGKAIAIANKETLVTAGHLVMRAAKEKNISLLPVDSEHSAILQALNGENTERIEKLVLTASGGSFRDKTREQLSEVTVKEALKHPNWNMGNKLTIDSATMFNKGLEVMEAHWLFGVDYDDIEVVIQRESIIHSMVQFVDGSFIAQLGTPDMRMPIQYALTYPDRLYIPYEKEFRITDFSALHFEKVDYERFPALKLAYNAGKIGGTMPTVLNAANEIAVAGFLNGQVAFYNIEALVENAMNRHTSISDPDLDTILQVDQETRAYVKTLL
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: YBEY_CHLP8
Sequence: MPLQIFNTTKRTIDEALLAEAIQLVIGEEGGKVGSIEAIYCGNKMIRRINRDFLNHDYATDTITFGYNEGGEVEGEFYISLDVIESNARRFGVMFEDELLRVTIHSALHLMGYDDETPELRIAMSRREDLYLDRIRGASNH
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1659_STRP8
Sequence: MTAILITGYRSFEIGIFDHKDPRVSIIKQAIRKDLIGYLENGVDWFIFTGNLGFEQWALEVANELKEEYPLQIATIFLFETHGDKWNEKNQEVLSQFKAVDFVKYYFPNYEQPTQFSQYYQFLLEKTEGAYVFYDTENETNLKYFLKKAKDMPHYQLLLLTFDRLNDMSQS
What are the official names of this protein?
UPF0398 protein spyM18_1659.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: FTSB_SALPB
Sequence: MGKLTLLLLALLVWLQYSLWFGKNGIHDYSRVNDDVVAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPGETFYRLVPDASKRAATAGQTHR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: H13_GLYBA
Sequence: MSDPAPEVASAVPVASPAKAKKEKKPKTDKPKKAKAPRTHPPVSEMVVNAIKTLKERGGSSLQAIKKFLAAQYKVDVDKLAPFIKKYLRGAVTKGELLQTKGKGASGSFKLPAAAKKEKVAKTPKKAAGEKKPQAAAKPKKALEKKKSIAKKPKAATATKVKKPVAKSTKKPAAVKPAAKKAAPKPKAAPKPKAATKPKKEVKPKKVAAKKPAEKKPEAAKKPAAKKA
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1-III.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: SELA_SALHS
Sequence: MTSETRTLYSQLPAIDRLLHDSAFLSLRDRYGHTQVVDLLRRMLDDARDVIRNTQTLPDWYADWAQEAKLRLENAAQSALRPVINLTGTVLHTNLGRALQAQEAIEAVTQAMRAPVTLEYDLDGAGRGHRDRALATLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHAKDYRQAVNENTGLLMKVHTSNYSIEGFTKTVEEAELAEIGRELDIPVVADLGSGSLVDLSQYGLPKEPMPQQLIAAGVSLVSFSGDKLLGGPQAGIIVGKKAMIAQLQSHPLKRALRADKMTLAALEATLRLYLHPEALAEKLPTLRLLTRSEASIREQAQRLQARLAARYGDEFALEVKPCLSQIGSGSLPVDRLPSAAMTFTPHDGRGSRLEALAARWRMLPVPVIGRIYDGRLWLDMRCLEDESRFMEMMLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_COXBR
Sequence: MNKNPFIVCLMGPTASGKTDLAIALARKLPFEIISVDSAMVYRGLDIGTAKPNEEELQLTSHRLINICDPSFPYSAGQFYKDALSEIKTIEIRNRTPLLVGGTMLYFHILEQGFSDLPTADETVRKKIQEEAAQHGWAKIHERLNAIDPKSAARINPNDAQRIQRAFEIYETTGQPLSSYQSLKRFKALPYQFINLILAPENRSWLHQRIEKRFDQMLKNNFLEEVRQLYNRGDLNSDLPAIRTVGYRQVWKYLSGEYDYEMMRHKAIAATRQLAKRQLTWLRRWPDAKWFNSEDKDLISQVVDYLKGIGM
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: YJW0_YEAST
Sequence: MCLFDQGKAVLVRTVGWPDLFVVGNIVTHIILWRVVKWRDPNGIGTKLFDVLQLGGNTLHITPTIVVGVFETCGINLINCGLFPPLGFCFWMCRRNSHCTLLSYLYEKTFTFVCVFGLVNGTYILVQLIPRVKKSSLLIYVCGRLTNDRK
What are the official names of this protein?
Putative uncharacterized protein YJL220W.
Protein: SRP54_BUCBP
Sequence: MFNNLTQRFLKIIKKISNKGRLTEKNIKETLREIRIALLEADVALPVVKNFIPSIQKSVIGNQVNKSLTPGQELIKIVKKELTLILGKENHSLNLSVTPPAIILMIGLQGSGKTTTTAKLGQLIRTKYKKKVIVTSIDIYRLAAIKQLKMLSKQAKISFFPSNNTQSPKDIVQHAIQHAKLKFYDVLLIDTAGRLQIDKKMMNELLDVYNISHPIETFFVADAMFGQDSINVINEFNKYLPVSSFIITKTDSDTRAGIILSIKYLTKKPIKFIGTGEKLEELELFYPDRIASRILGMGDMLSLIENIENKIDKKHIKKFSNTIKKYNTFNFNDMLLHINQIKKIGGVNSILGKLPKTQTIFNSFQNNIDENILLKMKTIINSMTISERHQPELIKGSRKRRISLGSGIPIPEINQLLKQFNNIKKIMKTIKKGGVTKIMQGINNIIKNKF
What is the function of this protein?
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane.  Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes.  The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.  Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
What are the official names of this protein?
Signal recognition particle protein, Fifty-four homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding SRP family. SRP54 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=The SRP-RNC complex is targeted to the cytoplasmic membrane.
Protein: FIEF_ECOBW
Sequence: MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGIQHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMMNGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVIIHQDPCSVVPREGKRSMLS
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLNB_PASMU
Sequence: MKKIEAIIKPFKLDDVRESLSDVGITGMTVTEVRGFGRQKGHTELYRGAEYMVDFLPKVKMEIVVTDEQVDQCIEAIMETAQTGKIGDGKIFVYDVERVIRIRTGEENEDAI
What is the function of this protein?
P-II indirectly controls the transcription of the glutamine synthetase gene (GlnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of GlnA.  When P-II is uridylylated to P-II-UMP, these events are reversed.  When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase by GlnE, so activating the enzyme (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: ISPD_CLOBK
Sequence: MSKNSVIIVAAGKGKRMNSSISKQFLQIKNKPILYYTLSKFSTHESIDEIVLVTLEDKIEVCGDIIDKYNINKVSKIVPGGKERQDSVYNGLKAVSKDCEVVLIHDAARPFVTSDIIENGIRYTNQYGAAACGVIPKDTIKIKSEKGFAIDTPNREDLFIVQTPQCFNYNIILDCHEKLKKHNKKVTDDTMVLENYGKSVYLYEGNYSNIKITTPEDLILGEQILEKLT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.