PharMolix/UniProtQA huggingface dataset:
Protein: FRDD_ECO8A
Sequence: MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGIVTI
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit D, Fumarate reductase 13 kDa hydrophobic protein, Quinol-fumarate reductase subunit D, QFR subunit D.
What is the protein family that this protein belongs to?
Belongs to the FrdD family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GALT_MOUSE
Sequence: MSHSGADPEQRQQASEADAMAATFRASEHQHIRYNPLQDEWVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGATRANGEVNPHYDGTFLFDNDFPALQPDAPDPGPSDHPLFRAEAARGVCKVMCFHPWSDVTLPLMSVPEIRAVIDAWASVTEELGAQYPWVQIFENKGAMMGCSNPHPHCQVWASSFLPDIAQREERSQQTYHSQHGKPLLLEYGHQELLRKERLVLTSEHWIVLVPFWAVWPFQTLLLPRRHVRRLPELNPAERDDLASIMKKLLTKYDNLFETSFPYSMGWHGAPTGLKTGATCDHWQLHAHYYPPLLRSATVRKFMVGYEMLAQAQRDLTPEQAAERLRALPEVHYCLAQKDKETAAIA
What is the function of this protein?
Plays an important role in galactose metabolism.
What are the official names of this protein?
Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, UDP-glucose--hexose-1-phosphate uridylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
Protein: FABA_PSEAE
Sequence: MTKQHAFTREDLLRCSRGELFGPGNAQLPAPNMLMIDRIVHISDVGGKYGKGELVAELDINPDLWFFACHFEGDPVMPGCLGLDAMWQLVGFYLGWQGNPGRGRALGSGEVKFFGQVLPTAKKVTYNIHIKRTINRSLVLAIADGTVSVDGREIYSAEGLRVGLFTSTDSF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length (By similarity).
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGKA_PIG
Sequence: MSKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAEYLQGDAIGYEGFQQFLKIYLEVDSVPSHLSLALFQSFQTSYCSEETVKRDVVCLSDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDRIIIQMMRMAEYLDWDVSELRPILQEMMKEIDYDGSGSVSLAEWLRAGATTVPLLVLLGLEMTLKDNGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQTHVWVRGGCESGRCDRCQKKIRIYHSLVGLHCVWCHLEIHDDCLPAMGHECDCGLLRDHILPPSSIYPSVLASGQERKVSKTSQKTTDDLNLSTSEALRIDPVSNTHPLLVFVNPKSGGKQGERVLWKFQYLLNPRQVFNLLKDGPEPGLRFFREVPDYRILVCGGDGTVGWILETIDKANLPFVPPVAVLPLGTGNDLARCLRWGGGYEGQNLGKILKDLEASKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVLNIPSTHGGSNLWGDTKRPHGDIHGINQALGAMAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGHRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHRNQMPMLVGPPPRSSNFFGFLC
What is the function of this protein?
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:8034597).  Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:8034597).  Also plays an important role in the biosynthesis of complex lipids.  Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group.  Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol (By similarity).
What are the official names of this protein?
Diacylglycerol kinase alpha, DAG kinase alpha, 80 kDa diacylglycerol kinase, Diglyceride kinase alpha, DGK-alpha.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic diacylglycerol kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RNC_LACLA
Sequence: MLKLQKKLKNDYGLVFNDEDLLKTAFTHSSFTNEERLPKIANNERLEFLGDVALSLVISDYLYRTYPEKLEGELSKMRSSIVRTESLANFSRSCGFGEFLRLGHGEEKMGGRDRETTLENLFEAFLGALFIDQGMDEVRKFIQHVVIPHVKNDDYVKVIDYKTELQEVLQIGGETTISYKILKEEGPAHDRSFVAAVFNNGKELGRGLGKSKKVAEQKAAENAIKGQNHVS
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_RUEPO
Sequence: MRILITNDDGINAPGLAALEQVALELAGPGGEVWTVAPAFEQSGVGHCISYTHPMLIARMGERRFAAEGSPADCVLAGLHDVMKDAPPDLVLSGVNRGNNSAENALYSGTLGGAMEAALQGLRAIALSQFFGPRNYGRTDPFEIAQSHGVQVIRRILDTWPQERPDYRLFYNVNFPPVPAAEVKGLRAVRQGFREGTRFSAEPHLSPSGKRFLWIKGGDQQQRTAPGTDAAANLDGYVSVTPMRADLTADDALEALQATL
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEAH4_ARATH
Sequence: MANLPILQFEEKIVETVEKNSVVVIIGETGSGKSTQLSQILHRHGYTKSGVIAITQPRRVAAVSVARRVAQELDVPLGEDVGYAIRFEDRTTSKTRIKYLTDGVLLRESLSNPMLDDYSVIILDEAHERSLNTDILLGLVKRLVRIRASNFKVLITSATLDGEKVSEFFSGCPVLNVPGKLYPVEILYSKERPVSYIESSLKVAIDIHVREPEGDILIFMTGQDDIEKLVSRLEEKVRSLAEGSCMDAIIYPLHGSLPPEMQVRVFSPPPPNCRRFIVSTNIAETSLTVDGVVYVIDSGYVKQRQYNPSSGMFSLDVIQISKVQANQRAGRAGRTRPGKCYRLYPLAVYRDDFLDATIPEIQRTSLAGSVLYLKSLDLPDIDILKFDFLDAPSSESLEDALKQLYFIDAIDENGAITRIGRTMSDLPLEPSLSRTLIEANETGCLSQALTVVAMLSAETTLLPARSKPSEKKRKHDEDSNLPNGSGYGDHIQLLQIFESWDRTNYDPVWCKENGMQVRGMVFVKDVRRQLCQIMQKISKDRLEVGADGRKSSSRDDYRKLRKALCVGNANQIAERMLRHNGYRTLSFQSQLVQVHPSSVLSADNDGMMPNYVVYHELISTTRPFMRNVCAVDMAWVAPIKRKIEKLNVRKLSGGPAPSFKVPEEKTELSKNNAETPAVSENVESRIEAARERFLARKGQK
What is the function of this protein?
May be involved in pre-mRNA splicing.
What are the official names of this protein?
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH4, DEAH RNA helicase homolog PRP22.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. PRP22 sub-subfamily.
Protein: RECF_MYCLB
Sequence: MYVRHFGLRDFRSWDHVDLELNPGRTVFFGPNGNGKTNLIEALWYSTTLSSHRVGTDIPLIRAGTIRAIVSTIVVNEGRECAIDLEIAAGRANRARLNRSLVRGMREVVGVLRAVLFAPEDLALVCGDPANRRRYLDDLATVRQPVIAAVRADYDKVLRQRTALLKSLAAARYRSDQGVLDTLDVWDTRLAEHGAELMAARIDLVNQLAPEVEKAYQLLAPGSRTASISYRASLDIGGIAGVGSSDRALLQADLLAGLSTRRNVELERGICLVGPHRDELELRLGDQPAKGFASHGESWSLAIALRLAAYELLRADGNEPVLLLDDVFAELDAARCRALATVAESAEQVLVTSAAQEDIPVGWDAKWVTVDLRDSDSGRVSVVYP
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPP_BACVZ
Sequence: MTNKNTSKDMHKNAPKGHNPGQPEPLSGSKKVKNRNHTRQKHNTSHDM
What are the official names of this protein?
Small, acid-soluble spore protein P, SASP P.
What is the protein family that this protein belongs to?
Belongs to the SspP family.
What are the subcellular locations of this protein?
Spore core.
Protein: ILVD_SALTI
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDSDFGKPIITVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMIQGADPKVSDDQSNQVERSACPTCGSCSGMFTANSMNCLIEALGLSQPGNGSLLATHADRKQLFLNAGKRIVELTKRYYEQDDESALPRNIANKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNRNVKNVLGLTLPQTLEQYDITVTQDEAVKKMFRAGPAGIRTTQAFSQDCRWDSLDDDRAAGCIRSLEYAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPVKVYESQDDAVEAILGGKVVEGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGTIALIEDGDTIAIDIPNRSIQLQLSEAEIAARREAQEARGDKAWTPKNRQRQVSFALRAYASLATSADKGAVRDKSKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: GLMU_FRAT1
Sequence: MGLSVVILAAGKGSRMNSNKPKVLQTLAAKTLIEHVVSSVEKLNPDNIVVVTGHLKEQVEDALQGRNITFVYQQQQLGTGHAVLQALPYLKEQKVLILYGDVPLISTEVLENLVDTTNDDDLGVLTAFVENPQGLGRIVRDKFGAVTEIVEEKDANDIQRQIKEINTGIYCVHKNLLQKWLPEIKANNVQKEYYLTDIITFAKADHVSINVTHPINEFEILGVNDRTQLASLERVWQRNVAEKIMAKGVSIADPNRFDVRGNLDVGKDCWIDINVIIKGNVKLGNNVVIGANCILKNCIIEDNVRIKSNSMVDGSIIREGAIVGPFARVRPECDVKEGAVIGNFVEAKKTILGKGSKASHLTYLGDSEIGANCNIGAGVITCNYDGVNKHKTVIGDYAFIGSDSQLIAPVNIGQGATVGAGSTIVKDVPADNLVISRARQRHIDTWQRSVKKTDK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_MESHJ
Sequence: MRQTTFVKHQEVKQKWFVIDAESKILGRLAAFVASRLRGKHYPHFTPNVDMGDKIIIINAEKILLTAKKEEQKLYYNHSGYPGGLRVRTAREMRAKKPIALLERAIYGMIPHTKLGDKQRKNLYVYSGSEHPHLGQNPEKLEVK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: NUOI_PSESM
Sequence: MFKYIGDIVKGTGTQLRSMVMVFGHGFRKRDTLQYPEEQVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETEDGRWYPDFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMADFKRQDLVYEKEDLLISGPGKNPDYNFYRVAGMAIGGKPKGAAQNEAEPINVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DPEP2_COCPS
Sequence: MSARDNEKGSARSQPSHAAASEIENVPRPSRQQSWTGTMIKVFIICACAGIVSKYIIPLDSIFKSVHIDPHDYATRANRILSTTPLIDGHNDLPYLIRLETKNKIYDHEKLPFRTGLLSHTDQIKIQEGKLGGQFWSVFVECATDPNAEIDDPTWAVRDTLEQIDVTKRLVQEYPDLLEYCESASCAKAAFKRGKVGSFLGIEGGHQIGNSLASLRQVYDLGVRYITVTHNCDNAFATAASTVAVGKPDLGLTDFGREFVKEMNRLGMLVDLSHVSHQTMRDILSVTKAPVMFSHSSSYALSKHLRNVPDDVLNGVTKNGGVVMVTFVPSFLKVDDPASATIHDAVDHILHVAKVAGWDHVGIGSDFDGTADVPEGLENVSKYPRLIELLLERGVTDEQARKLIGENILRVWSNVEEIAENIRALGEKPNEETWSGRKWTAAIDIPMPFMFKDSADKRKEL
What is the function of this protein?
Hydrolyzes a wide range of dipeptides.
What are the official names of this protein?
Putative dipeptidase CPSG_01350.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: THIE_CLOB1
Sequence: MEINYELYLITDRRFLKGRQLKKVVEDAILGGVTIVQVREKDVSTREFYNVAKEVKEVTDYYKVPIIINDRLDIAQAIDASGVHLGQKDMHLNIAREILGKDKIIGISVGNVKEALQAQNNGADYLGIGTIFPTGSKKDVDAIIGIDGLSKIKDSISIPSVAIGGINKTNFKDVLKTGIEGISVISAILDEDDIKLAANNLLINK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: GREA_VIBCH
Sequence: MEKVPMTARGEKLLREELDRLLKLRPKITEAIAEARELGDLKENAEYHAAREEQGICEAQIRDIEYKLSVAQVIDVTKMENSGKVIFGATVTVIDVNSDEEKTYQIVGDDEADIKSGRISVNSPIARGLIGKFEGDEVSIATPGGNKVFEIDRVEYL
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MNHE2_STAAU
Sequence: MNQIVLNIIIAFLWVLFQDEDHFKFSTFFSGYLIGLIVIYILHRFFSDDFYVRKIWVAIKFLGVYLYQLITSSISTINYILFKTKDMNPGLLSYETRLTSDWSITFLTILIIITPGSTVIRISQDSKKFFIHSIDVSEKEKDSLLRSIKHYEDLILEVSR
What is the function of this protein?
Expression of the mnh2 operon in E. coli is not able to catalyze Na(+)Li(+)/H(+) antiport.  It does however confer higher growth rates than the control strain at up to pH 9. 5.  The operon may encode an NADH-ubiquinone oxidoreductase.
What are the official names of this protein?
Putative antiporter subunit mnhE2, Mrp complex subunit E2, Putative NADH-ubiquinone oxidoreductase subunit mnhE2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENDA_METTH
Sequence: MRVEGQLGDEVVTIKATSIARRLHGKSHYGKMYEDRLQLSLIEAAYLMERGKLKLMKDDDEVSPEEFISLLGERGLYSKYLVYRDLRNRGYIVKTGFKYGAEFRLYERGGAPGRTHSAYLVRVISENDTIHALDFSSYVRVAHGVNKKLLMAFLDDEEDITYYLVDWIRP
What is the function of this protein?
Endonuclease that removes tRNA introns.  Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron.  The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini.  Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
What are the official names of this protein?
tRNA-splicing endonuclease, tRNA-intron endonuclease.
What is the protein family that this protein belongs to?
Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
Protein: PG094_VACCW
Sequence: MGGGVSVELPKRDPPPGVPTDEMLLNVDKMHDVIAPAKLLEYVHIGPLAKDKEDKVKKRYPEFRLVNTGPGGLSALLRQSYNGTAPNCCRTFNRTHYWKKDGKISDKYEEGAVLESCWPDVHDTGKCDVDLFDWCQGDTFDRNICHQWIGSAFNRSNRTVEGQQSLINLYNKMQTLCSKDASVPICESFLHHLRAHNTEDSKEMIDYILRQQSADFKQKYMRCSYPTRDKLEESLKYAEPRECWDPECSNANVNFLLTRNYNNLGLCNIVRCNTSVNNLQMDKTSSLRLSCGLSNSDRFSTVPVNRAKVVQHNIKHSFDLKLHLISLLSLLVIWILIVAI
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG094, EFC protein OPG094, Myristoylated protein G9, Protein F1.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG086 family.
Protein: VP2_POVS1
Sequence: MGAALALLGDLVATVSEAAAATGFSVAEIAAGEAAAAIEVQIASLATVEGITSTEAIAAIGLTPQTYAVITGAPGAIAGIAALVQTVSGVSSVAQVGYKFFSEWDHKISTVGLNQQPGMALELFNPEDYDILFPGVNTFVNNIQYLDPRHWGPTLFSAISQAFWHLVRDDLPRLTSQEIERRTQRFFRDSLAKFLEETTWTIVNAPINLYNSIQNYYSALSPIRPSMVRQVAEREGTQVTFGHSYSQSIDDADSIEEVTQRLDLRNKEANVHSGEFIEKTLAPGGANQRIAPQWMLPLLLGLYGTVTPALEAYEDAPSKKKRRMSRGSSQKAKGPRASSKTSYKRRRRSTRS
What is the function of this protein?
Viroporin inducing perforation of cellular membranes to trigger virus progeny release.  Forms pores of 3 nm inner diameter.  VP4 is expressed about 24 hours after the late structural proteins and is not incorporated into the mature virion (By similarity).
What are the official names of this protein?
Minor capsid protein VP2, Minor structural protein VP2.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses capsid protein VP2 family.
What are the subcellular locations of this protein?
[Isoform VP2]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane. SUBCELLULAR LOCATION: [Isoform VP3]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane. SUBCELLULAR LOCATION: [Isoform VP4]: Host nucleus.
Protein: SAST_ANAPL
Sequence: MDKVIARPYKRPNALCRLICFPWAGGNCSFFIRWCEAFSSIIVVSVIRLAGRECRDTEPFPEDMAEVVNEITNALLKDLQEKPFALFGHSFGSFVSYALAVHLKEKHGLEPVHMFFSGSYGPHSEYFHLMYKLPEVEDSRLLELIHTLGGTPPEFLQNEQITKHLLRVLKEDQKVLVTYPWHDVRKKYFSCDLTCFNGSDEKNHGSEAWIAITSGDTSIYSLPGNHFYLMEPSNETFLIKYITKCIENSDI
What is the function of this protein?
In fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase I, a component of the fatty acid synthetase complex.  The chain length of the released fatty acid is usually C16.  However, in the mammary glands of non-ruminant mammals, and in the uropygial gland of certain waterfowl there exists a second thioesterase which releases medium-chain length fatty acids (C8 to C2).
What are the official names of this protein?
S-acyl fatty acid synthase thioesterase, medium chain, Thioesterase II.
What is the protein family that this protein belongs to?
Belongs to the thioesterase family.
Protein: ATPG_HERA2
Sequence: MASAREIRRRIKSVKNTGKITKAMELVSASKMRRAQRNVLATRPYADRLYDVMGELTLRSMGGGTKHPLLQPHPTVTRVALILITPDRGLCGALNSNLTRAAARFITDQKSQGRSVSVIAIGKKGRDFILRVGQKLDSEIIGLGDAPPLVDVLPAATTAINGYSPDASGNYDYDEVYLLCAEFVNTLVQRPKLRRFLPVEAPGNAGATKVDYSYEPSQEDVLDQLLPRFIEVQLYQAILESIASEHSARMMAMRNANDNAKELVRDLTLTYNKARQAAITTEISEIAAGATALNQ
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MURG_SALEP
Sequence: MSGQPKRLMVMAGGTGGHVFPGLAVAHHLMSQGWQVRWLGTADRMEADLVPKHGIDIDFIRISGLRGKGVKALLAAPLRIFNAWRQARAIMKRFKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNQWLAKIATTVMQAFPGAFPNAEVVGNPVRTDVLALPLPQVRLAGRDGPIRVLVVGGSQGARVLNQTMPQVAARLGDTVTIWHQSGKGVQHTVEQAYAGVGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPAIFVPFQHKDRQQYWNALPLENAGAAKIFEQPQFTVEAVADTLAGWSREALLTMAERARAVSIPDATERVASEVSRVART
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MRAY_COXBU
Sequence: MLLWLTNFLSQHFHAFRVFNYLTFRSIVSALTALILVLSLSPRLIKYLVSLQVGQMVRNDGPQTHLKKSGTPTMGGVLIIVAIVISVLLWGDLSNRFIWVILLVTVAFSAIGWMDDYRKIIRKNSKGLSARSKYLLQSIIGALAAVYLYFSATTGAETALVIPFLKNVLPNLGLFYIVLAYFVIVGSSNAVNLTDGLDGLALMPTVMIGAALGVFAYTTGNHFFAQYLAIPYIPGAGEVVVFCSALVGAGLGFLWYNTYPAQVFMGDVGSLGLGAALGVTAVVVRQELVYFLMGGIFVAETLSVILQVGYFKLSGGKRIFRMAPLHHHFELKGWPEPKVIVRFWIITFILVLCGLATLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ISCA2_PONAB
Sequence: MAAARGLSLTAATQKAVTPWPRGRLLAASLGPQARREASSSSPEAGEGQIRLTDSCVQRLLEITEGSEFLRLQVEGGGCSGFQYKFSLDTVINPDDRVFEQGGARVVVDSDSLAFVKGAQVDFSQELIRSSFQVLNNPQAQQGCSCGSSFSIKL
What is the function of this protein?
Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway.  May be involved in the binding of an intermediate of Fe/S cluster assembly.
What are the official names of this protein?
Iron-sulfur cluster assembly 2 homolog, mitochondrial, HESB-like domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: APT_CAEEL
Sequence: MTLPRFDQIRPKIEQHIREVKDFPKKGINFRDIMPLFTNPQLVNELCVVIADHVRHTVGHVDSVAGLEARGFLFGPQVAIQLGVPFVPIRKKGKLPGATIEASYVKEYGEDRVEIQEGAIKNGDIVFLIDDLLATGGTLRAATDLVVKAGGKVGEAFVLIELAPLNGRSKLPDVNLTTLISYDSA
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.