PharMolix/UniProtQA huggingface dataset:
Protein: SLRP_SALT1
Sequence: MFNITNIQSTARHQSISNEASTEVPLKEEIWNKISAFFSSEHQVEAQNCIAYLCHPPETASPEEIKSKFECLRMLAFPAYADNIQYSRGGADQYCILSENSQEILSIVFNTEGYTVEGGGKSVTYTRVTESEQASSASGSKDAVNYELIWSEWVKEAPAKEAANREEAVQRMRDCLKNNKTELRLKILGLTTIPAYIPEQITTLILDNNELKSLPENLQGNIKTLYANSNQLTSIPATLPDTIQEMELSINRITELPERLPSALQSLDLFHNKISCLPENLPEELRYLSVYDNSIRTLPAHLPSEITHLNVQSNSLTALPETLPPGLKTLEAGENALTSLPASLPPELQVLDVSKNQITVLPETLPPTITTLDVSRNALTNLPENLPAALQIMQASRNNLVRLPESLPHFRGEGPQPTRIIVEYNPFSERTIQNMQRLMSSVDYQGPRVLFAMGDFSIVRVTRPLHQAVQGWLTSLEEEDVNQWRAFEAEANAAAFSGFLDYLGDTQNTRHPDFKEQVSAWLMRLAEDSALRETVFIIAMNATISCEDRVTLAYHQMQEATLVHDAERGAFDSHLAELIMAGREIFRLEQIESLAREKVKRLFFIDEVEVFLGFQNQLRESLSLTTMTRDMRFYNVSGITESDLDEAEIRIKMAENRDFHKWFALWGPWHKVLERIAPEEWREMMAKRDECIETDEYQSRVNAELEDLRIADDSDAERTTEVQMDAERAIGIKIMEEINQTLFTEIMENILLKKEVSSLMSAYWR
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway.  Can ubiquitinate both ubiquitin and host TXN (thioredoxin).  Leads to significant decrease of thioredoxin activity and increase of host cell death.
What are the official names of this protein?
E3 ubiquitin-protein ligase SlrP, RING-type E3 ubiquitin transferase SlrP, Secreted effector protein SlrP.
What is the protein family that this protein belongs to?
Belongs to the LRR-containing bacterial E3 ligase family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via type III secretion systems 1 and 2 (SPI-1 and SPI-2 TTSS), and delivered into the host cytoplasm.
Protein: DAPE_NAUPA
Sequence: MNVIDLFKKLLSFKSVTPDDDGGMEFIKEYLKGFEVIESEKEGVKNLFIYKKFGEGDHLCFGGHIDVVPPGEGWNTDPFTPTEKEGFIYARGAQDMKSGLAAFLWAMKNAKNFKGTLSALITSDEEGDAVWGTKYMLEILKDKNLIPDYAIVAEPTCEKVFGDAIKIGRRGSINGVLKKIGLQGHAAYPEKSINPIHKVAQVLHKIAGVDLDDGDEFFAPSKFVVTDIRAGMEVTNVTPGELKMMFNVRNNTHTDKEKIKNFIHEHFKDMNYTLELKQSAEPFVTNPDTKVVKALDRAIKNHTNITPQHSTAGGTSDARFFAKHGVKVVEFGVKNDTIHAPNERTTPEEVNKLADIFKEVIEEWN
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: ASB6_HUMAN
Sequence: MPFLHGFRRIIFEYQPLVDAILGSLGIQDPERQESLDRPSYVASEESRILVLTELLERKAHSPFYQEGVSNALLKMAELGLTRAADVLLRHGANLNFEDPVTYYTALHIAVLRNQPDMVELLVHHGADVNRRDRIHESSPLDLASEEPERLPCLQRLLDLGADVNAADKHGKTALLHALASSDGVQIHNTENIRLLLEGGADVKATTKDGDTVFTCIIFLLGETVGGDKEEAQMINRFCFQVTRLLLAHGADPSECPAHESLTHICLKSFKLHFPLLRFLLESGAAYNCSLHGASCWSGFHIIFERLCSHPGCTEDESHADLLRKAETVLDLMVTNSQKLQLPENFDIHPVGSLAEKIQALHFSLRQLESYPPPLKHLCRVAIRLYLQPWPVDVKVKALPLPDRLKWYLLSEHSGSVEDDI
What is the function of this protein?
Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 6, ASB-6.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPNE_DROPE
Sequence: MDQELMDFFDFSKEFVRKQAPRGHVSSNVHAFVTESDELEKPIKREIVGKDYVKSFVEKEKKRMNGIFSSDEMASRRNKSLDDMDSDEEYEASPEIRTDAEFYEKYYFNLNRDKSLPIYAKREEIINAINENPVVIVKGETGCGKTTQVPPILFWMMVSKAKQYCNIVVTQPRRIAAISIANRVCQERQWQPGTVCGYQVGLHRQLERFADTRLLYCTTGVLLNILVNNKTLTHYTHIVLDEVHERGQEMDFLLIVIRRLLATNSRHVKVILMSATINPRELSDYFANESSAPPVIAASYGRNFTVEKYYRDQLQSINWEGHQEDINSPGITQEGYRSAIKTILVIDNMERNERGTGKSYNQSLREGSILIFLPGVGEINNMSDMLKDMANHDPIMKFNMVRCHSLMTSEDQREIFQPSPPGYRKIIMATNVAESSITVPDVSYIIDFCLEKVLVTDTSTNFSSLRLAWASKTNCRQRAGRVGRLRNGRVYRMVTKSFYQRELSEYSVPEMLRSPLQNCVLKAKELKMGTPVEMLALALSPPNLSDICNTILMLKEVGALFPTMDGTYDPRDGDITYWGTIMSKLPLDTHLSRLIILGYVFNLVDEAIIIAAGLTVRGIYIDSARLGADNYWMHYVFADGSGSDLVGIWRVYLTYLNMCENGLQKDASIQWAKRFHLSLRALSEMHLLVQDLRLRCEKLSLLPLNFPTHRISDDREKAIMLKVIIAGSFYPNYFVQSKSTSGDDRNMFSVISGLDPCRTVYFTSFTDRTMGELYTRKVKQLFPEAQIPPENMDVTFGQGSEKIFVTFKNDIYKPEGTTYVHVPGRIKAEVYKALRLRTYCNQHSLRVMEPMNALKYVKDKKIGKIVEGRWIPPSKPVAVELLALPSLFDKIIIGRITNIVSCGKFFFQPESFENCIANMSEHFNNPQQLQNCVRNAGAITKGLMLLAKRQGKYQRATVVRVDTQDSRNVRFYVRFVDYGDIERLPMAQLRLMSQDLLRHYRDLPPRLFECRLALVQPASMVSTYNAWPQKADDMLHALAKGGRVQLEIYSLVQNVAAVMIHLREGNLNELLVKEKLARRTDEDYMSRVDHDFRMRKQECRGYVSQQERQQVNEEYLRSKQLPQDMDLSPPPPEECNSLITLKGPFSTLESRVFSTMRSGMSKTVRIDPCSVNFVLLDTEPQDQHAKMVVAASISAAGRHNDVLTLRSTSIMPNIPGFAAIMTLIFCPRAQLKANTANSRYVSILAGIGYHPQTMQSYYEDHDLVINLDVNIDEHDVLLINQIRYMIDSAFFNLEGELHPTAGHADRVLIHNTIYPALNRLLSKNRNFIECNPNSSDYVWQDMEESGEPDPQPYGRRSIFPMHTIPELHEEKMDTVLDLIANCKEMYDYRNFEGSFDPMTCSLCKQYLESVAELRLHLLTQLHLDREKEVGYPID
What is the function of this protein?
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity.  Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons.  Involved in the repression of LTR retrotransposon copia.  Also involved in telomere regulation by repressing specialized telomeric retroelements HeT-A, TAHRE, and TART; Drosophila telomeres being maintained by transposition of specialized telomeric retroelements.  Involved in telomeric trans-silencing, a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin.  Involved in the repression of testis-expressed Stellate genes by the homologous Su(Ste) repeats.  Required for anteroposterior and dorsoventral axis formation during oogenesis (By similarity).
What are the official names of this protein?
Probable ATP-dependent RNA helicase spindle-E, Homeless.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis.
Protein: RPOC_FRAAA
Sequence: MLDVNFFDELRIGLATADDIRQWSHGEVKKPETINYRTLKPEKDGLFCEKIFGPTRDWECYCGKYKRVRFKGIICERCGVEVTRAKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLEKVIYFAAYMITKVDAEARHRDLPTLEARMGVEKQQLEDKKNADVETRQKRLETDLAQLEAEGAKGDARRKVRESAEREMRQIRDRAQRKIDDLDRVFDRFKNMKVQDLEPDELLYRELRDRFGQYFDGGMGAEALQRRLADFDLAAEAESLRETIRSGKGQKKARALKRLKVVSAFLNTRNSPMGMVLDCVPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPEIIVNNEKRMLQEAVDALFDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKQMALELFKPFVMKRLVDLNHAQNIKSAKRMVERARPVVWDVLEEVITEHPVLLNRAPTLHRLGIQAFEPQLVEGKAIQIHPLVCTAFNADFDGDQMAVHLPLSAEAQAEARILMLSSNNILSPASGRPLAMPSLDMVTGVFHLSTLAEGAVGEGRAFSSVAEAQMAFDAREIALQARISVRLRDTTPPSDWVPPADWVTGDVFTLETTFGRCLLNEALPEGYPFINAQLNKKAQAAIVNDLAERYPKIQVAATLDALKSAGFYWATRSGVTVAIEDVVAPPNKAEILDDYEQRADRVQKQFDRGFLSDEERRSELVQIWTEATNKIAEAMEKNFPQTNPVYVLVNSGAAGNMMQIRQLAGMRGLVSNPKGEIIPRPIKANFREGLTVLEYFISTHGARKGLADTALRTADSGYLTRRLVDVSQDVIVREEDCGTERGILTRIARRGADGVLVRDRYAETSAYARTLASDAVDEHGEIIVPAGTDAGDVAIGQIIEAGIESVRVRSALTCESRMGVCAQCYGRSLATGKLVDVGEAVGIVAAQSIGEPGTQLTMRTFHSGGVAGDDITQGLPRVVELFEARSPKGKAPITEVSGRVKIEETEKTFKVVVVPDDGSEEIAYPVSRRSRLRVREGDRIEVGNQIVDGAVDPHEVLRILGPRQVQLHLVDQVQEVYRSQGVSIHDKHIEIIIRQMLKRVNVLESGETNLLPGELCERARFESENRRVVESGGQPASARPVLMGITKASLATESWLSAASFQETTRVLTDAAINARSDSLVGLKENVIIGKLIPAGTGISRYRNIRVEPTEEARAAMYSVGAYEDGGSVEYGAFGTGSGQAVPLDEFDYRSSGDFR
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: HIS7_BACP2
Sequence: MRQAETARKTNETNISLTLEIDGEGKADIQTDVPFMTHMLDLFTKHGHFNLTVDAKGDTDVDDHHTTEDIGIVLGQMFKEALGDKKGIKRYGSSFVPMDETLAQVVVDLSNRPHLEMRAAFPSQKVGTFDTELVHEFLWKFALEARINLHVIVHYGTNTHHMIEAIFKAMARALDEATTIDPRVKGIPSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_ECO7I
Sequence: MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDATGMEAKIKAWLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: TRUA_ECOBW
Sequence: MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: VRTN_BOVIN
Sequence: MTSREQLVQHVLQELQEAVESEGLEGLVGAALEAKQVLSSFALPTRRGGGPGPQVLEVDSVALSLYPEDAPRNMLPLVCQGEGSLLFEAASLLLWGDAGLSLELRARTVVEMLLHRHYYLQGMIDSKVMLQAVRYSLRSEESPEMTSLPSATLEAIFDADVKATCFPSSFSNVWHLYALASVVQRNIYSIYPLRNLKIRPYFNRVIRPRRCDHTPATLHIMWAGQPLSGHLFRHQYFAPVVGLEEVEAESAHPGPAPLPPPAKTLELLNREPGLSYSHLGEHSSVTKSTFYRWRRQSQEHRQKVATRFSAKHFLQDSFHRGGVVPLQQFLQRFPEISRSTYYAWKHELVGSGACQALTPTEELTKLPERQVAEGLGCSSTAASSPGVVFMQRAKLYLEHCIALNTLVPYRCFKRRFPGISRSTYYNWRRKALRRNPSFKPVPALLESGPPQPVPVGEKALLPWKGGEVGEGAAKATGGGPPAPRAFLPLRVPLSRWQRRLRRAARKQVLGGHLPFCRFRLRYPSLSPSSFWVWKSLARSWPGSLSKLHIPAPTLGRGSRKEAEEKEAGRNVIAAVAPPEGTWPMAASPGQDPNGQVLVMDMLATTKFKAQAKLFLQKRFQSKSFPSYKEFSTLFPLTARSTYYMWKRALYDGLTLVDG
What are the official names of this protein?
Vertnin.
What is the protein family that this protein belongs to?
Belongs to the vertnin family.
Protein: RECR_NEIMB
Sequence: MMSHKKQDAFQGLIDALKVLPNVGPKSAQRIAYHLLQHKRKEAEKLVDALQTALKQVYHCAMCNTFCEGGLCDICADETRDGRRLMVVHMPADVSNMEAANCHDGLYFVLMGQINTALGMDVSAIALDRLAQRLGGGEVEEIIIATAFTAEGNATAYVLSEFFKNLPYKVSRLSQGIPLGGELEYVDAGTLAQAVYERRLIKEGGA
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: 3603L_ASFM2
Sequence: MQPSTLQALTKRVLATQHVSNDDYCILERCGLWWHDAPITLYTDGEQILIKTPYYKEGIKLNTALVLAVKENNYDLIVLFTEWGANINYALLSVNKEYTRNLCRNLGAKEGLEASEVLRFFFETKRHKTSSNIILCHELFSNNPFLQNVNMVELRMIIYWELKDLITNLIVNENSFTEMLTKYWYGIAVKYNLKEAIQYFCQEYEHLNEWRLICALSFNNVFELHEICNTMNIDMNINKMMRLACMRDNNFLTIYYCFALGADINRAMYGSVSNFRIENMFFCMDLGADAFEESLELAERHGYSVIVDILSLKIYKANPILLAKETNPEKINTLLKNYYPKNMLAYDIYRIDNYL
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 360-3L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
Protein: EFGL_MYCTU
Sequence: MADRVNASQGAAAAPTANGPGGVRNVVLVGPSGGGKTTLIEALLVAAKVLSRPGSVTEGTTVCDFDEAEIRQQRSVGLAVASLAYDGIKVNLVDTPGYADFVGELRAGLRAADCALFVIAANEGVDEPTKSLWQECSQVGMPRAVVITKLDHARANYREALTAAQDAFGDKVLPLYLPSGDGLIGLLSQALYEYADGKRTTRTPAESDTERIEEARGALIEGIIEESEDESLMERYLGGETIDESVLIQDLEKAVARGSFFPVIPVCSSTGVGTLELLEVATRGFPSPMEHPLPEVFTPQGVPHAELACDNDAPLLAEVVKTTSDPYVGRVSLVRVFSGTIRPDTTVHVSGHFSSFFGGGTSNTHPDHDEDERIGVLSFPLGKQQRPAAAVVAGDICAIGKLSRAETGDTLSDKAEPLVLKPWTMPEPLLPIAIAAHAKTDEDKLSVGLGRLAAEDPTLRIEQNQETHQVVLWCMGEAHAGVVLDTLANRYGVSVDTIELRVPLRETFAGNAKGHGRHIKQSGGHGQYGVCDIEVEPLPEGSGFEFLDKVVGGAVPRQFIPNVEKGVRAQMDKGVHAGYPVVDIRVTLLDGKAHSVDSSDFAFQMAGALALREAAAATKVILLEPIDEISVLVPDDFVGAVLGDLSSRRGRVLGTETAGHDRTVIKAEVPQVELTRYAIDLRSLAHGAASFTRSFARYEPMPESAAARVKAGAG
What are the official names of this protein?
Elongation factor G-like protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
Protein: NDB4T_HOFGE
Sequence: MKTQVIIFIMAVVFLQLLSQSEAFIFDLLKKLVGKRELRNIDLDQFDDMFDEPEISAADMRFLQELLK
What is the function of this protein?
Antibacterial peptide with activity against both Gram-positive and Gram-negative bacteria probably by forming pores in the cell membrane (By similarity).  Has also weak hemolytic activity (By similarity).  Does not show antifungal activity (PubMed:27917162).
What are the official names of this protein?
Non-disulfide-bridged peptide 5.6, NDBP-5.6.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Short antimicrobial peptide (group 4) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.
Protein: RM38_MOUSE
Sequence: MAAPWWRAAFFGIGRCRGFSTSAFLSRRTPPLGPMPNEDIDVSNLERLEKYRSFERYRRRAEQEARAPHWWRTYREHFVKETDPKDKIDIGLPPPRVSRTQKLLERKHFLRELRANVEEERAARLRTASIPLEAVRAEWERTCGPYHKQRLAEYYGLYRDLFHGATFVPWVPLHVAYAVGEEDLIPVYHGNEVTPTEASRAPEVTYEADKDSLWTLLFINLDGHLLEPDAEYVHWLLTNIPSNRVAEGQETCPYLPPFPARGSGFHRFAFLLFKQDKPINFSEDTRPSPCYQLAQRTFRTFDFYKRHQEAMTPAGLAFFQCRWDDSVTHTFHQLLDMREPVFEFVRPPPYHPKQKRFPHEQPLRYLDRYRDSHEPTYGIY
What are the official names of this protein?
39S ribosomal protein L38, mitochondrial, L38mt, MRP-L38.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family. Mitochondrion-specific ribosomal protein mL38 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FETP_VEREI
Sequence: MARTVQCIKLGKEAEGLDFPPYPGELGQRIWANVSKQAWAGWLKHQTMLVNENRLNLADARARQYLARQMENHFFGSGADAAAGYVPPSA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: GB_HHV6G
Sequence: MSKMVVLFLAVFLMNSVLMIYCDPDHYIRAGYNHKYPFRICSIAKGTDLMRFDRDISCSPYKSNAKMSEGFFIIYKTNIETYTFPVRTYKKELTFQSSYRDVGVVYFLDRTVMGLAMPVYEANLVNSHAQCYSAVAMKRPDGTVFSAFHEDNNKNNTLNLFPLNFKSITNKRFITTKEPYFARGPLWLYSTSTSLNCIVTEATAKAKYPFSYFALTTGEIVEGSPFFNGSNGKHFAEPLEKLTILENYTMIEDLMNGMNGATTLVRKIAFLEKADTLFSWEIKEENESVCMLKHWTTVTHGLRAETDETYHFISKELTAAFVAPKESLNLTDPKQTCIKDEFEKIINEVYMSDYNDTYSMNGSYQIFKTTGDLILIWQPLVQKSLMFLEQGSEKIRRRRDVVDVKSRHDILYVQLQYLYDTLKDYINDALGNLAESWCLDQKRTITMLHELSKISPSSIVSEVYGRPISAQLHGDVLAISKCIEVNQSSVQLHKSMRVVDAKGVRSETMCYNRPLVTFSFVNSTPEVVPGQLGLDNEILLGDHRTEECEIPSTKIFLSGNHAHVYTDYTHTNSTPIEDIEVLDAFIRLKIDPLENADFKVLDLYSPDELSRANVFDLENILREYNSYKSALYTIEAKIATNTPSYVNGINSFLQGLGAIGTGLGSVISVTAGALGDIVGGVVSFLKNPFGGGLMLILAIVVVVIIIVVFVRQRHVLSKPIDMMFPYATNPVTTVSSVTGTTVVKTPSVKDVDGGTSVAVSEKEEGMADVSGQVSDDEYSQEAALKMLKAIKSLDESYRRKPSSSESHASKPSLIDRIRYRGYKSVNVEEA
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: GFRP_BOVIN
Sequence: MPYLLISTQIRMEVGPTVVGDEHSDPELMQHLGASKRSVLGNNFSEYYVNDPPRIVLDKLERRGFRVLSMTGVGQTLVWCLHKE
What is the function of this protein?
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1.  This inhibition is reversed by L-phenylalanine (By similarity).
What are the official names of this protein?
GTP cyclohydrolase 1 feedback regulatory protein, GFRP, GTP cyclohydrolase I feedback regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the GFRP family.
What are the subcellular locations of this protein?
Nucleus. Nucleus membrane. Cytoplasm, cytosol.
Protein: LIPA_SULAC
Sequence: MKSEVVVRINENFKKLSRIVSEKGISTVCEEALCPNIMECWGSGTATFMIMGDICTRGCRFCYVKKGKPVLLDHEEPIKVAEAVREMGLDYVVITSVDRDDLADGGASHFSQVVKAVKEMNPDVIVEVLTPDFMGNKELVEKVIGSGVDVFAHNVETVRSLTPLVRDARASYEQSLRVLSYAKNVVKKSSILLGLGESLEEVVETMKDLRNVGVDILVLSQYMRPSIKQLEVKKRYNMEEYKELEKIAYSLGFSYVVALPHARTSYRAKEAYLRAMANVKNNNRWS
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_STRA3
Sequence: MEDQLTIFIISDSLGETAKAIAKACLSQFPGHDDWHFQCFSYINSQERLEQVFEEASQKTVFMMFSLVDVALASYAQKRCESEHYAYVDLLTNVIQGISRISGIDPLGEPGILRRLDNDYFKRVESIEFAVKYDDGRDPRGILQADLVIIGISRTSKTPLSMFLADKNIKVINIPLVPEVPVPKELRMIDSRRIIGLTNSVDHLNQVRKVRLKSLGLSSTANYASLERILEETRYAEEVMKNLGCPIINVSDKAIEETATIILEILKTNGQVAKNL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: ILVC_STRR6
Sequence: MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDVIIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGNAVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGNAKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAGYAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMKAVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDDAFKIYN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: YBEY_BACFR
Sequence: MAITYQTEGIKMPDIKKRETTEWIKAVAATYEKRIGEIAYIFCSDEKILEVNRQYLQHDYYTDIITFDYCEGNRLSGDLFISLETVKTNSEQFNTPYEEELHRTIIHGILHLCGINDKGPGEREIMEAAENKALAMRKQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_RHILW
Sequence: MISEAPPFWWRKADWRAWLLLPVSFLYGRIAGHRMAHGRRASVAIPVICVGNFTVGGAGKTPTALTIARAAKAKGLKPGFLSRGYGGSLDVTTVVDPDHHRAVAVGDEPLLLAREALTVISRRRVDGAQRLVAEGADLIIMDDGFQSARLAIDYALLVIDATRGLGNGHIVPAGPVRAPIRQQLRSATALLKVGGGNAADRIVRMAARAAKPYFTASLKVRGDNTLAGMKVLAFAGIADPAKFFRTVESRGAEITVAKSFGDHEHLTEDEIDDILTTAERQDLLIVTTSKDFVRLSGHPGKAAQLAEKCRVIEVDMVFEDHLAPSLIIDRAIVACRERRLREMKAGIKAMPGKAGPL
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: YAW8_SCHPO
Sequence: MSENALLALQRHFEDQFGHIEGLQPVSAKPSETAFNSDASEKEQSPTTSNEEEDAISDMEDKEDVSFGSKILRVSHQEVEKPTLSATVGRVSFLKKMPKLEDEEEILAKKREEQKLRKRSRQNDDGSDDDEVENLKNDLELQKLLRESHLLHEATSRTGQVQLVAEGKIRHKVVQQHIAQLGGKKETEKMPMAARRGMKKKQKHIEKVIENEARESGTVLAKKRKERKQFKKGFRPVTFSAPGKLVGGTLLLPKSMIPK
What are the official names of this protein?
Uncharacterized protein C3F10.08c.
Protein: F187B_HUMAN
Sequence: MPPMLWLLLHFAAPALGFYFSISCPSGKQCQQALLSGNDILLYCNSSGAHWYYLFTQGKKGRLTSLTNISNMEIMPEGSLLIKDPLPSQTGLYHCWNKNGRQVVQYEIDFQDVTTLHITHKDLGQRPLQNETLHLGSKQLIFTWWEPWQDCNRCEEPGECKRLGYRYIEEPLEEAMPCWLYLGEVLVWSSRLRPELQVEACHVQCTNNTQLRVDYVIFDNFRLDEKTEFVWLDCPLGSMYRPVNWRANDTPLTWESQLSGQDFTTFLDPSTGGRQLQVFQPAVYKCFVQQELVAQFKPAASLETLEAQWRENDAQWREARKALRGRADSVLKGLKLVLLVVTVLALLGALLKCIHPSPGRRSTQVLVVK
What are the official names of this protein?
Protein FAM187B, Transmembrane protein 162.
What is the protein family that this protein belongs to?
Belongs to the FAM187 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.