PharMolix/UniProtQA huggingface dataset:
Protein: NDC80_DEBHA
Sequence: MNVDYPMNNIPQASSLLRKNNGKRLSMASAARTSLLGNLNLNGTSGGASGRNSNIIDSSSLSMGNTGKRRSLLSTPASINRRRQSSLLQAPMSSSQMSSQSQQASQQTQAPFNQDQRPLRDKNYQTLIQQEIYDFLLANKFELEMNHPLTFKTLKQPTQKDFVVIFQFLYNKIDPYYRFTKSIETEVFLLLKILNYPYLDGINRSQISAVGGQNWPNFLGMLYWLVKLNLSVLNLNSKVDLISPDDEFDKIFINYITQSYRAFIDERDDYSEYYDEMKSRFDELNNNIIQDIENISNENNELLNQYNELNGQLDILENSEKKSKALENDLIKFKAYIETMESRKSKWSEILNKITQEIGNCEVELNNIESVKRDYEAQIGQQGLTPNDIDNLNTERDKLSKSIDLISNSLEDLKDVYHNKQINLQKNYQSLENFLKQYNNLIYKIQLKNHNYDYNFEINFRNNTIINETPDLLKPNEIINKNLKDEKIQLLNYKSIINTNVHMHQDEQIKLQEQIDLISELIMERREEIETLEAKLTANKSTYDEIYETMINDTTTYSMQIEKLERELRSIKINTNQGFIEVENKFQNIQIEYDELLYEIHSNRSILHDKIQKIIESTIGFKINIQSNLEDLENLAFDEFEKEDKKLNKN
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein NDC80.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: CTX_PSEAI
Sequence: MNDIDTITNAWGRWKTAQYGTTCWFTESTQYGRNKDTRSYMQHQTNVSAPKDLVYSNFVQQDGGSTLLGQYDMINEGSQVIELAVNLQQGLVDTFTWSVTEQLKVGVEVKVKANIPLVGGAEITSTVELSLSSTQGASTSKSSNYGASTKVLISPHSHGWGEVALSFTELRTQWVGNVGLQGYVAIWFNNKVALNNDGDYHYLWFIPVEQVFWECVQHNIVNTSGYVVQGNGVLAQATGTFHSSVGLNLKTIAHERPYPETSEAVRTFYNYASLVPDLETRVRSAE
What is the function of this protein?
Cytotoxin is thought to form hydrophilic pores in cell membranes.
What are the official names of this protein?
Cytotoxin, Leucocidin.
What is the protein family that this protein belongs to?
Belongs to the aerolysin family.
What are the subcellular locations of this protein?
Secreted. Note=Produced as a cell-associated inactive precursor which is not secreted extracellularly. The toxin is converted into its active form by the action of proteases concomitantly with cell lysis and is released into the medium.
Protein: PURA_META3
Sequence: MTCTIVVGGQWGDEGKGKIISYICEKDKPSVVARGGVGPNAGHSVEVDGKKYGIRMVPTGFPNRSSKLAVGAGVLVDVDVLLKEVEMLKEFNIKDRVIIDYNCGVIEEKHKEMDKSNSHLSKEIGSTGTGCGPANVDRAMRTLRLAKEFDALKPFLGDVSDLVNEALENGENVLIEGTQGTLLSLYYGSYPYVTSNDTSASAFASDVGIGPTKVDEVIVVFKSYPTRVGEGPFPTEMDVEEAEKLGLVEYGTVTGRRRRIGYFDYDLAKKVCRLNGATAIALTCLDKYDEECHGLTNYDDITEKGLAFIKEIEEKVGVPVKIISTGPELHQTIDIR
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_XANCB
Sequence: MTEQRTIASSATREDEAADASIRPKRLADYLGQQPVRDQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGVSLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTPDGAAEIARRARGTPRIANRLLRRVRDFAQVKAAGHIDLAVAQAAMQMLKVDPEGFDELDRRMLRTIVDHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVTPKAYLHLGLKPPRDRAPAIGEPGDLF
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: PHS_DROME
Sequence: MLLTIKCAQNVIKPNCQKVANLLASSRRAGLFPTTATTATSRSLSQISVLYSPAAREAARAATGGSANLRRIHNTPTTEATATAITAKKRKMVVRLNEQERAEKLQPLLDAGWTLVEGRDAIFKQFVLKDFNQAFSFMTGVALLAEKINHHPEWFNCYNKVDVTLSTHDVGGLSSQDIRMATHLETTANLLK
What are the official names of this protein?
Pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: IDI2_BACVZ
Sequence: MTRAERKREHINHALSTGQNRETGLDDITFVHVSLPNLALEKVDISTKIGGLTSSSPIFINAMTGGGGQLTYEINRSLARAARKAGMPLAVGSQMSALKDPSERCSYEIVRKENPDGLIFANLGSEADAEQAKMAVDMIQADALQIHLNVIQEIVMPEGDRSFTGALGRIERIAAEAGVPVFVKEVGFGMSRESARQLFDAGAAAVDAGGYGGTNFSKIENMRREKALQFFNTWGISTAASLAEIHSLSADQSIIASGGLQSALDVAKSIALGASGAGMAGTFLKALTSKGEEGLFDEMTALLQELKMIMTALGCQSVSQLQKAPLVIKGDTHHWLSERGIDTSRFSRR
What is the function of this protein?
Involved in the biosynthesis of isoprenoids.  Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase, IPP isomerase, Isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Type 2 isopentenyl diphosphate isomerase, IDI-2.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL19_SYNWW
Sequence: MQNIIKSIEEEYYKKDLPRFGPGDTVKVHVKVVEGTRERLQVFEGTVIKIRGTGLSQTFTVRRTTSGVGVERTFPLHSPKIARIEVTRRGKVRRGRLYYLRQLTGKKARVKEKGRY
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: RF1_STRP6
Sequence: MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTRETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKMNEVIDALVMYDQTKKLESLNN
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEPF_MYCLE
Sequence: MSTLHKVKAYFGMAPMEDYDDEYYDDRSPTHGYGRSRFEEGYGRYEGRDYSDLRGDPTGYLPLGYRGGYGDEHRFRPREFDRPDLSRPRLGSWLRNSTRGALAMDPRRMAMLFDEGSPLSKITTLRPKDYSEARTIGERFRDGTPVIIDLVSMDNADAKRLVDFAAGLAFALRGSFDKVATKVFLLSPADVDVSPEERRRIAETGFYAYQ
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: CMOA_NAUPA
Sequence: MEDKVFNKPIEKQFEFDEEVASVFDDMLNRSVPFYKENLNLQIDILKNFLSDQDKIIDLGSSTGTFLIELAKKKENLDLIGIDNSEAMIKRAKNKARAFGVKVEFINSDFLEYDLSGSKAIVANYTVQFIRPLKREKLIKKIYDSLKNDGIFLMSEKLITENKKLNKIMIDIYYDYKKQMGYSEFEIAQKREALENVLIPYTMQENIEMLKNAGFKEIEVVFRWNNFATFIAFK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: Y420_NEIMA
Sequence: MQHDVYDYTAHTVSKNTVLQKTYRLLGFSFIPASAGAALAANAGFNFYAAFGSRWIGFAVVLAFFYGMIHFIEKNRYSNTGVTLLMVFTFGMGVLIGPVLQYALHIADGAKIVGIAAAMTAAVFLTMSALARRTRLDMNALGRFLTVGAVILMVAVVANLFLGIPALALTISAGFVLFSSLMIMWQVRTVIDGGEDSHISAALTLFISLYNIFSSLLNILLSLNGED
What are the official names of this protein?
Uncharacterized protein NMA0420.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_SHEPC
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGAAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: TLP1_ORYSJ
Sequence: MPRETPPPPPPEGGEVHEVVEGEDGQAEDQEERWARLLPELMSEVVRRVEASGGERWPARKDVVSCACVCRRWRDAAVAVVRPPAESGKITFPSSLKQPGPREFPMQCFIKRNKKNSTFYLYLGLTNATVDKGKFLMAARRFRRGPHTEYIVSLDADDLSQGSNAYMGKLRSDFWGTNFKIYDSKPPYDGAKASSSRSSRRFGSRRISPQVSAGNYEVGQVSYKYNLLKSRGPRRMYCALECPSTQETWENCLKTKFRKPTGNTVLRNKAPRWHEHLQCWCLNFHGRVTVASVKNFQLVAAADPNDPASSKDEETVLLQFGKVDDNIFTMDYRQPLSAFQAFAISLSSFGTKLACE
What are the official names of this protein?
Tubby-like F-box protein 1, OsTLP1, Tubby-like F-box protein 9, OsTLP9.
What is the protein family that this protein belongs to?
Belongs to the TUB family.
Protein: YHD5_SCHPO
Sequence: MEDPKSDEKFDIGISEKNLDVGFGESSSVDVPVKGRFASFLKKLELSSGPEKENIDLRPTPPDRRHYSALDIIYLWSCNGISASAFRTGTSYMEMGLSPKQALAALIAGNVFIAMPMTLNGLFGSHYHIPFAVQSRASFGYYFNTLIILLRFIAGLFYYGTNVYTGAECVQTILYAIFKSFRSYKNRLPADAGITSDFLISYFVYWVISFPFHLIRPEYLQRFFLIKSISTYIACFAMLIFLLCNVGSHVVWDQPATVSGRSWSWVFMCALNSSVAGFSTLAVNVNDFTRYVKHPKTPYVQMLILPLVAAVSAPIGIVSGVASKIMYGTAMWDPLQIANNWTSRGGRAAAFFMGLTYLVSMIAQNISDNTVAAANDLLYFFPRYLDIRRAQVIVIIIGAWAIVPWKILQNGTAFLAFLGSLSIFLGPAAGIFVADKFKNHHKYDIDEFYNPSGIYRYNKLGLNWRALIAFLCACVPLIPGMAMSINPSITMPDGVIHLYYIGYFYSFMTAFLIYWGLNLVFPAKETLLEEAVYPPKSNAELVDPSTLSGKDKFWYYIDY
What are the official names of this protein?
Uncharacterized permease C1683.05.
What is the protein family that this protein belongs to?
Belongs to the purine-cytosine permease (2.A.39) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: RF3_STRP8
Sequence: MSLTEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLGIASYPMNWPIGMGRAFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKEDIELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGNVIDPLAKDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSPKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWISEDDLDQRMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVTLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H332_CAEEL
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPTTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDMQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3 type 2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Depleted from the meiotically silenced X chromosome.
Protein: PSD_BURCJ
Sequence: MNYPHPIIAREGWPFIAIAAVIALLIHAVGGFGFAWPFWLLLVFVVQFFRDPQRPIPAQPNAVLCPADGRIVAVETAQDPYANREALKISVFMNVFNVHSQRSPVDGAISKVEYFPGAFLNAAIDKASTENERNAVVIQTASGKTVTSVQIAGLIARRILCYVRAGEPLSRGQRYGFIRFGSRVDVYLPLGSRAKVSIGEKVYASSTILAELEQ
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GSA_THET2
Sequence: MEGMERPISEAYFQEAKRHIPGGVSSPVRAFKAVGGTPPFLVRGEGAYVWDADGNRYLDYVMSWGPLILGHAHPKVLARVRETLERGLTFGAPSPLEVALAKKVKRAYPFVDLVRFVNSGTEATMSALRLARGYTNRPYIVKFRGNYHGHADGLLVEAGSGALTLGVPSSAGVPEEYAKLTLVLEYNDPEGLREVLRRRGEEIAAIIFEPVVGNAGVLVPTEDFLKALHEAREFGVLLIADEVMTGFRLAFGGATELLGLKPDLVTLGKVLGGGLPAAAYAGRREIMEKVAPLGPVYQAGTLSGNPLAMAAGLATLELLEENPGYYRYLEDLGARLERGLKEVLAQKGIPHAVNRVGSMVTVFFTEGPVVTFQDAKRTDTELFKRFFHGLLDRGIYWPPSNFEAAFLSVAHTEEDVEKTLEALGEAL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IVD_MOUSE
Sequence: MATAIRLLGRRVSSWRLRPSPSPLAVPRRAHSILPVDDDINGLNEEQKQLRHTISKFLQENLAPKAQEIDQTNDFKNLREFWKQLGSLGVLGITAPVQYGGSGLGYLEHVLVMEEISRASGAVGLSYGAHSNLCVNQIVRNGNEAQKEKYLPKLISGEFIGALAMSEPNAGSDVVSMKLKAEKKGDHYVLNGNKFWITNGPDADILVVYAKTDLTAVPASRGITAFIVEKGMPGFSTSKKLDKLGMRGSNTCELVFEDCKVPAANVLSQESKGVYVLMSGLDLERLVLAGGPLGIMQAVLDHTIPYLHVREAFGQKIGQFQLMQGKMADMYTRLMASRQYVYNVAKACDEGHIIPKDCAGVILYAAECATQVALDGIQCLGGNGYINDFPMGRFLRDAKLYEIGAGTSEVRRLVIGRAFNADFR
What is the function of this protein?
Catalyzes the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA as an intermediate step in the leucine (Leu) catabolic pathway.  To a lesser extent, is also able to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters as pentanoyl-CoA, hexenoyl-CoA and butenoyl-CoA.
What are the official names of this protein?
Isovaleryl-CoA dehydrogenase, mitochondrial, IVD, Butyryl-CoA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: FEZF1_MOUSE
Sequence: MDSSCLNATTKMLATAPARGNVMSTSKPLAFSIERIMARTPEPKALPVPHFLQGAVPKGDPKHSLHLNSSIPCMIPFVPVAYDTNSKAGVNGSEPRKASLEVPAPPAVAPSAPAFSCSDLLNCALSLKGDLARDALPLQQYKLVRPRVVNHSSFHAMGALCYLNRGDGPCHPAASVNIHPVASYFLSSPLHPQPKTYLAERNKLVVPAVEKLPSGVAFKDLSQAQLQHYMKESAQLLSEKIAFKTSDFSRGSPNAKPKVFTCEVCGKVFNAHYNLTRHMPVHTGARPFVCKVCGKGFRQASTLCRHKIIHTQEKPHKCNQCGKAFNRSSTLNTHTRIHAGYKPFVCEFCGKGFHQKGNYKNHKLTHSGEKQFKCNICNKAFHQVYNLTFHMHTHNDKKPFTCPTCGKGFCRNFDLKKHVRKLHDSSLGLTRTPTGEPSSDPPPQLQQPPPAPLPPLQPTLPPPGPLPSGLHQGHQ
What is the function of this protein?
Transcription repressor.  Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN).  Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation.  Expression is required in OSN to cell-autonomously regulate OSN axon projections.  Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons.  May be required for correct rostral migration of the interneuron progenitors.
What are the official names of this protein?
Fez family zinc finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACCA_XANCB
Sequence: MNPNYLDFEQPIADLEAKIQELRKASTGPAVNVDAEVRALRDKLRVRTAQIFRDLSAWQVSQLARHPQRPYTLDYINTMCDEFQELAGDRAYADDKAIVGGLGRIDGRPVVIIGHQKGRDTKSKVARNFGMPRPEGYRKALRLMKLAERFRLPLLTFIDTPGAYPGIGAEERGQSEAIARNLMEMAELKVPVICTVIGEGGSGGALAIGVGDRTLMLEYGTYSVISPEGCASILWKDAAKAKDAAEQLGLTAKRLKGLGLVDKVIREPTGGAHRNPEQMGKRLKAVLLNELDALEKVPVDALMQQRYERLRSYGAYEGH
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_STAA1
Sequence: MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVDGYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVGQEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDASRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKGNK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HEM3_MARSD
Sequence: MRKITIATRGSKLALWQANHISDLLREEYPGIEVQLLKIKTKGDKILDVPLAKVGGKGLFVKEIEEALLDGRADLAVHSMKDVPTELPEGLEVGIIPPREAETDTLLSVKYDSLKDLPAGAVVGTSSLRRQSQVLALRDDLKIESLRGNLDTRVGKLLNGEFDAIVVATAGLNRLKLSAPKSEILGPPTFLPAVAQGALGIEYRIEDTEIQDILAFLHDEMTARQVKAERGFLTGLDGGCQVPIAAWSQLESDQVKLTGFVADIDGSSPIRMEKTGPAEDAWDIGLALAEEVLAAGAKEILDRVYDKC
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: AGUA_GEOSE
Sequence: MTAGYEPCWLRYERKDQYSRLRFEEIVAKRTSPIFQAVVEELQKGLRSMMEIEPQVVQEVNETANSIWLGTLEDEEFERPLEGTLVHPEGYVIRSDVDDGPFRIYIIGKTDAGVLYGVFHFLRLLQMGENIAQLSIIEQPKNRLRMINHWDNMDGSIERGYAGRSIFFVDDQFVKQNQRIKDYARLLASVGINAISINNVNVHKTETKLITDHFLPDVAEVADIFRTYGIKTFLSINYASPIEIGGLPTADPLDPEVRRWWKETAKRIYQYIPDFGGFVVKADSEFRPGPFTYGRDHAEGANMLAEALAPFGGLVIWRCFVYNCQQDWRDRTTDRAKAAYDHFKPLDGQFRENVILQIKNGPMDFQVREPVSPLFGAMPKTNQMMEVQITQEYTGQQKHLCFLIPQWKEVLDFDTYAKGKGSEVKKVIDGSLFDYRYSGIAGVSNIGSDPNWTGHTLAQANLYGFGRLAWNPDLSAEEIANEWVVQTFGDDSQVVETISWMLLSSWRIYENYTSPLGVGWMVNPGHHYGPNVDGYEYSHWGTYHYADRDGIGVDRTVATGTGYTAQYFPENAAMYESLDTCPDELLLFFHHVPYTHRLHSGETVIQHIYNTHFEGVEQAKQLRKRWEQLKGKIDEKRYHDVLERLTIQVEHAKEWRDVINTYFYRKSGIDDQYGRKIYR
What is the function of this protein?
Alpha-glucuronidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.  It catalyzes the cleavage of alpha-1,2-glycosidic bond of the 4-O-methyl-D-glucuronic acid side chain of xylan and releases 4-O-methylglucuronic acid from xylan.
What are the official names of this protein?
Xylan alpha-(1->2)-glucuronosidase, Alpha-glucuronidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 67 family.
Protein: YCF35_SKECO
Sequence: MSHFTNLKTSFKNLFHLENALNKLEIPYKREKKAIDANNSKHHNVNLVIPQSNNYDITFNWNGEEYELVLDASFWIQPYPVESFINKLSQHYANDVIITESQKIGFQPVKSKQHVDGSNTITLATLEFKK
What are the official names of this protein?
Uncharacterized protein ycf35.
What is the protein family that this protein belongs to?
Belongs to the ycf35 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FBID_THET1
Sequence: MSAMNIAVLVPVKKLDKAKMRMADTLDRSQRRQLMMVTLRRVLSALQKAQIGDVYLVASDPQVKNIACDLCVKFIPDQGDELNPSLELARGELCQNYDALLVVFGDLPMISDKDIKTIVRLGSSKPSCVIAPDKRNVGTNVLFLHPPYLLPFTFGGNSYERFRSNCEKLGVQFLVYQSQNTALDLDYPQDILDLAALRGHKISGLEEILDPGVLAQISQVTSMSGAKMGA
What is the function of this protein?
Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP.  It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.
What are the official names of this protein?
Phosphoenolpyruvate guanylyltransferase, PEP guanylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CofC family.
Protein: FBX22_HUMAN
Sequence: MEPVGCCGECRGSSVDPRSTFVLSNLAEVVERVLTFLPAKALLRVACVCRLWRECVRRVLRTHRSVTWISAGLAEAGHLEGHCLVRVVAEELENVRILPHTVLYMADSETFISLEECRGHKRARKRTSMETALALEKLFPKQCQVLGIVTPGIVVTPMGSGSNRPQEIEIGESGFALLFPQIEGIKIQPFHFIKDPKNLTLERHQLTEVGLLDNPELRVVLVFGYNCCKVGASNYLQQVVSTFSDMNIILAGGQVDNLSSLTSEKNPLDIDASGVVGLSFSGHRIQSATVLLNEDVSDEKTAEAAMQRLKAANIPEHNTIGFMFACVGRGFQYYRAKGNVEADAFRKFFPSVPLFGFFGNGEIGCDRIVTGNFILRKCNEVKDDDLFHSYTTIMALIHLGSSK
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Promotes the proteasome-dependent degradation of key sarcomeric proteins, such as alpha-actinin (ACTN2) and filamin-C (FLNC), essential for maintenance of normal contractile function.
What are the official names of this protein?
F-box only protein 22, F-box protein FBX22p44.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere, Z line.