PharMolix/UniProtQA huggingface dataset:
Protein: AP4B_DICDI
Sequence: MTSTANYNNSGKDSYFSEIKKSELGLIKNNLSTAINERNADKIKDILQRIIYYMTIGMDVSVLFPDVIMVASSNDIIIKKLVYLYIVHYSKSNPDLLLLVVNTLRRDCIDRNPIIRGLALRSLCSLDSKNTLEYATIEINRSLTDFSGYVRKTALLGLAKLYHLSKEAFDLDIIIPKIFDMIMDQDPQVIVNAVSTLNEIKPGWSFTFDLVQHLMIKFKEFNEWSQCIILECLSRYTPSSEDESLDILNLLDDRLSHSNSALTLSTIKIFLKYTDEFEEIQEQVYERIKEPLITLMESSESNETSFTILHHIHLLMSRSPRLFNRYYKHFYCKFDDPLYIKTLKVQVLKEIASNQTFIESIDEILQELSEYVYEGDHSLCKQSINAITVIAQKHKNTQEKYPIDESVLEKIFLPYLSVSSNLGGAGDDNISINEGILSFILISLKDFLRVFPKHLKTVLPYINENLIGIGSVSNYTLPPSANESVLWMLGESPNSQVNSPYIIEEFFNEKFDQQPTFVKTQLLTTSLKVFFDRPGEMLPILKRILKKCCSDLSQDPGLHEISLFYSRIILLLDIDKAASIINSSKQTTSINTFLEDEINEYRDKIFDEFNTLSVLFGKHSTKFIKNKKQIENEKLQFLENQKNYLLSITDGNQNNNQNNNQNNNQNNNQNNNQNNQNNNNQNNNSKQLLKEIESSPNNLIDTFILDQQPELSPELFQSLWLSLEDGHKIDIQLDSPIDNSEIESVMSKQGIICLAFGSVDQQTKLYYYARQNLSFDIDFNSEQNQQQPQPIFIIEILIDENTLLMSILFKSPILKTLHNKFIPKFLSILSIPIPKIFN
What is the function of this protein?
Probable component of an adaptor protein complex.  Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection.  They control the vesicular transport of proteins in different trafficking pathways.
What are the official names of this protein?
AP-4 complex subunit beta, AP-4 adaptor complex subunit beta, Adaptor-related protein complex 4 subunit beta, Beta subunit of AP-4, Beta4-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes large subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Protein: RL13_XANOP
Sequence: MTTFTAKSETVQRDWYLVDAAGKTLGRLSTELARRLRGKHKPVYTPHVDTGDYLVVINAEKIVVTGNKLKDKKYHRFTGYIGNLKTESLEQALQRHPERVIEIAVKGMLPKGPMGRTMYRKLKVYSGAEHPHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: LAP1_LEPMJ
Sequence: MRSSVLFSLYAATLVAAVAHPKDPQIVLQESQATIVEPDEYLIELSPGETRWVTEDDKWALRRENINFFDITHNKELGTLNHKLSTESVKFPSKPAHNESIVPLLKELKKENMRTHLETFTSFHTRYYKSHYGAESSAWLLEQVRKTLTDAGASKASVKAFPHPWGQASIIATIPGKSDKTVVIGAHQDSINLFLPSILAAPGADDDGSGTVTILEALRVLLKSEEVLKGEADNTIEFHWYSAEEGGLLGSQAIFQSYEKEGRDVKAMLQQDMTGYVQKTLDAGEPESVGVITDFVHPGLTEFIKKIITVYCDIPYVLTKCGYACSDHASASKAGYPSAFVIESDFKYSDNKIHTTEDKIEYLSFDHMLQHARLTLGLVYELAFAKFK
What is the function of this protein?
Extracellular aminopeptidase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Leucine aminopeptidase 1, Leucyl aminopeptidase 1, LAP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28E subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_MARSD
Sequence: MQILNGKETALTIREELKVEIDGLKEKHGRAPGLAVILVGEDPASQVYVRNKEIACEKAGIVSTAHRIDASVSQEELEALIQKLNADDTIDGILLQLPLPKGLDSQRCLELIDPGKDVDGFHPMNVGKLMLGLPGFRSCTPAGIITLLERYNLPTSGKKAVVVGRSNIVGKPLAMMLMQYGDFANATVTVCHSRTDNLAEEVKAADFVFAAIGIPKFIKKEMVKDGAVVVDVGINRTDEGLVGDCDYAALEDVASAMTPVPGGVGPMTIAQLLINTVQAYKEHVGA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: KLD8B_MOUSE
Sequence: MAAGGGRAFAWQVFPPMPTCRVYGTVAHQDGHLLVLGGCGRAGLPLDTAETLDMGSHTWLALAPLPTARAGAAAVVLGKQVLVVGGVDEVQSPVAAVEAFLADEGRWERRATLPQAAMGVATVERDGMVYALGGMGPDTAPQAQVLVYEPRRDCWLSLPSMPTPCYGASTFLHGNKIYVLGGRQGKLPVTAFEAFDLETRTWTRHPSLPSRRAFAGCAMAEGSVFSLGGLQQPGPHNFYSRPHFVNTVEMFDLEHGSWTKLPRSLRMRDKRADFVVGSLGGNIVAIGGLGNQPCPLASVESFSLARRRWEVLPAMPTARCSCSSLQAGPRLFVIGGVAQGPSQAVEALCLRDGV
What is the function of this protein?
Involved in pinching off the separated nuclei at the cleavage furrow and in cytokinesis.  Required for mitotic integrity and maintenance of chromosomal stability.  Protects cells against mitotic errors, centrosomal amplification, micronucleus formation and aneuploidy.  Plays a key role of midbody function involving abscission of the daughter cells during cytokinesis and appropriate chromosomal and nuclear segregation into the daughter cells.
What are the official names of this protein?
Kelch domain-containing protein 8B.
What are the subcellular locations of this protein?
Cytoplasm. Midbody. Note=In mitotic cells, concentrates in the midbody of the cytoplasmic bridge linking daughter cells as they are about to separate during cytokinesis.
Protein: Y759_TREPA
Sequence: MLMQPLTFLTCVYLWYSAALCVEVKIVRTDLLSSASVGR
What are the official names of this protein?
Uncharacterized protein TP_0759.
Protein: RIHA_ENT38
Sequence: MALPIILDCDPGHDDAIALVLALASPELALKAVTSSAGNQTPDKTLRNVLRMLTLLNRTDIPVAGGARKPLMRDLIIADNVHGETGLDGPALPEPTFKPQACTAVELMVKVLRESDEPVTLVATGPQTNVALLLNSHPELHRKIARIVIMGGSMGLGNWTPAAEFNIFVDPEAAEIVFQSGLPIVMAGLDVTHRAQIMSADVERFRAIGNPVATTVAELLDFFMEYHKAEKWGFHGAPLHDPCTIAWLLKPELFTTVDRWVGVETQGKYTQGMTVVDYYSLTGNKPNTTLMVDIDRQGFVDLLAERLAQFSIR
What is the function of this protein?
Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: NCOA2_HUMAN
Sequence: MSGMGENTSDPSRAETRKRKECPDQLGPSPKRNTEKRNREQENKYIEELAELIFANFNDIDNFNFKPDKCAILKETVKQIRQIKEQEKAAAANIDEVQKSDVSSTGQGVIDKDALGPMMLEALDGFFFVVNLEGNVVFVSENVTQYLRYNQEELMNKSVYSILHVGDHTEFVKNLLPKSIVNGGSWSGEPPRRNSHTFNCRMLVKPLPDSEEEGHDNQEAHQKYETMQCFAVSQPKSIKEEGEDLQSCLICVARRVPMKERPVLPSSESFTTRQDLQGKITSLDTSTMRAAMKPGWEDLVRRCIQKFHAQHEGESVSYAKRHHHEVLRQGLAFSQIYRFSLSDGTLVAAQTKSKLIRSQTTNEPQLVISLHMLHREQNVCVMNPDLTGQTMGKPLNPISSNSPAHQALCSGNPGQDMTLSSNINFPINGPKEQMGMPMGRFGGSGGMNHVSGMQATTPQGSNYALKMNSPSQSSPGMNPGQPTSMLSPRHRMSPGVAGSPRIPPSQFSPAGSLHSPVGVCSSTGNSHSYTNSSLNALQALSEGHGVSLGSSLASPDLKMGNLQNSPVNMNPPPLSKMGSLDSKDCFGLYGEPSEGTTGQAESSCHPGEQKETNDPNLPPAVSSERADGQSRLHDSKGQTKLLQLLTTKSDQMEPSPLASSLSDTNKDSTGSLPGSGSTHGTSLKEKHKILHRLLQDSSSPVDLAKLTAEATGKDLSQESSSTAPGSEVTIKQEPVSPKKKENALLRYLLDKDDTKDIGLPEITPKLERLDSKTDPASNTKLIAMKTEKEEMSFEPGDQPGSELDNLEEILDDLQNSQLPQLFPDTRPGAPAGSVDKQAIINDLMQLTAENSPVTPVGAQKTALRISQSTFNNPRPGQLGRLLPNQNLPLDITLQSPTGAGPFPPIRNSSPYSVIPQPGMMGNQGMIGNQGNLGNSSTGMIGNSASRPTMPSGEWAPQSSAVRVTCAATTSAMNRPVQGGMIRNPAASIPMRPSSQPGQRQTLQSQVMNIGPSELEMNMGGPQYSQQQAPPNQTAPWPESILPIDQASFASQNRQPFGSSPDDLLCPHPAAESPSDEGALLDQLYLALRNFDGLEEIDRALGIPELVSQSQAVDPEQFSSQDSNIMLEQKAPVFPQQYASQAQMAQGSYSPMQDPNFHTMGQRPSYATLRMQPRPGLRPTGLVQNQPNQLRLQLQHRLQAQQNRQPLMNQISNVSNVNLTLRPGVPTQAPINAQMLAQRQREILNQHLRQRQMHQQQQVQQRTLMMRGQGLNMTPSMVAPSGMPATMSNPRIPQANAQQFPFPPNYGISQQPDPGFTGATTPQSPLMSPRMAHTQSPMMQQSQANPAYQAPSDINGWAQGNMGGNSMFSQQSPPHFGQQANTSMYSNNMNINVSMATNTGGMSSMNQMTGQISMTSVTSVPTSGLSSMGPEQVNDPALRGGNLFPNQLPGMDMIKQEGDTTRKYC
What is the function of this protein?
Transcriptional coactivator for steroid receptors and nuclear receptors (PubMed:8670870, PubMed:23508108, PubMed:9430642).  Coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) (PubMed:8670870, PubMed:23508108, PubMed:9430642).  Required with NCOA1 to control energy balance between white and brown adipose tissues (PubMed:8670870, PubMed:23508108, PubMed:9430642).  Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC1 expression (PubMed:8670870, PubMed:23508108, PubMed:9430642).  Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3 (PubMed:23508108).  Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK-BMAL1 heterodimer (By similarity).
What are the official names of this protein?
Nuclear receptor coactivator 2, NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2.
What is the protein family that this protein belongs to?
Belongs to the SRC/p160 nuclear receptor coactivator family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDE1B_BOVIN
Sequence: MELSPRSPPEMLESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEVNIEELKKNLEYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQTRAKGPSEEKPKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNVDLWCFDVFSLNRAADDHALRTIVFELLTRHNLISRFKIPTVFLMTFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIEVLAIIFAAAIHDYEHTGTTNSFHIQTKSECAILYNDRSVLENHHISSVFRMMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKSMKTALQQLERIDKSKALSLLLHAADISHPTKQWSVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPTGDDDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWTKYIQENKQKWKERAASGITNQMSIDELSPCEEEAPASPAEDEHNQNGNLD
What is the function of this protein?
Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.  Has a preference for cGMP as a substrate.
What are the official names of this protein?
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Cam-PDE 1B, 63 kDa Cam-PDE.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL14_TRIV2
Sequence: MIQPQTYLNVADNSGARKLMCIRVLGAGNSRYGFIGDKIIAVVKDATPNMAVKKSDVVEAVIVRTRHHIRRDSGMTIRFDDNAAVIINKDGNPRGTRVFGPVARELRDKNFTKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: FIEF_SHIFL
Sequence: MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGIQHLVSPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMMNGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVIIHQDPCSVVPREGKRSMLS
What is the function of this protein?
Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+).  May be involved in zinc and iron detoxification by efflux.
What are the official names of this protein?
Cation-efflux pump FieF.
What is the protein family that this protein belongs to?
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. FieF subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS11_NITEC
Sequence: MIKPPLKSRKKIKKNIIEGVAHIHASFNNTIVTISDRQGNALSWATSGGVGFKGSRKSTPFAAQVAAEHAGRAALEYGVKNLEIRVKGPGPGRDSAVRALNATGFKITSITDVTPVPHNGCRPPKKRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: EFG1P_PICGU
Sequence: MPKSVPSRQGSASADIYNSGSAKIKKKIRDIERLLKKDNVPANIRIDNERALKALKVELANKQQDHKTQKIAKKYHMVRFFERKKALRKLKQARKELQNVSETGERKDIKKARKVVRHCEIDVAYVVLFPKAEKYISLYPNHQPEKNPDTENAKKGLEKTESRRRELRKKVEKLVDDKALPFSIDDLLEGKSVDVKHDFESGHNQEIDAPETKIQEEDDFFE
What is the function of this protein?
Involved in rRNA processing.
What are the official names of this protein?
rRNA-processing protein EFG1.
What is the protein family that this protein belongs to?
Belongs to the EFG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: O161H_CONCL
Sequence: GLGRPSRECIEGSEPCEVFRPYTCCSGHCIIFVCAR
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal6.1h.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BIOB_CUTAK
Sequence: MTERGLRGESITREEALEILRSSDDELMSIIAAAGKVRRHFFDNRVRLNYLVNLKSGLCPEDCSYCSQRLGSRAEIMKYSWADPQKVHDAVEAGIAGGARRVCMVASGHGPSRRDVERVNGMVRSLKADHPDVEVCVCLGFVDDEKAASIKEAGADAYNHNANTARSHYGKICSTHSYEDRMDTVEVLKRNGLSPCSGVIAGMGETDEEFVDVIFDLRKHGVDSVPVNFLLPFEGTPLAGGAQHITPQWCLKRLAMVRFAHPDSEVRAAAGREQHIRTMQPLALEVVNSIFLGDYLTSEGAAGAADLQMIEDGGFIPEGADGQPMVHTDVNSHHSANLPVNAVPIRHRGIGTEVPANA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: PLPHP_VIBCH
Sequence: MRSIQQNIEHITAQIESAQQKCGRARSSVQLLAVSKTKPVEAILEATQAGQRYFGENYVQEGVDKIRYFAEHHPQLALEWHFIGPLQSNKTRLVAEHFDWVHTIDREKIALRLSEQRPVNMPPLQVLIQVNTSGEASKSGIEPQQLFTLAELISRLPNLTLRGLMSIPENVPDYPAQLAAFTQLAELQQQLAQKYPQIDTLSMGMSGDMQAAIEAGSTIVRIGTAIFGERDYSRNA
What is the function of this protein?
Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.
What are the official names of this protein?
Pyridoxal phosphate homeostasis protein, PLP homeostasis protein.
What is the protein family that this protein belongs to?
Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
Protein: RL11_ENCCU
Sequence: MSSKKINPMREISIKKLSIHICARESGAKLDRAAKVLEQLTGQKPVTSKARMTIRNFGIRRNEKIAVHVNVSGKKAYELLNTALRVKEYELKESCFSNNGCFGFGIEEHIDLGLKYDPNIGIFGMDFFVILARPGDRVSKRKRCKSRVGNKQRVYAEDAKKWFVENFEGVLVE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: REGQ_BPVT2
Sequence: MRDIRQVLERWGAWAANNYEDVTWSPIAAGFKGLIPEKVKSRPQCCDDDAMVICGCIARLYRNNRDLHDLLVDYYVLGETFMALARKHGCSDTCIGKRLHKAEGIVEGMLMMLGVRLEMDRYVERELPGGRTSVFYQRKNSLRS
What is the function of this protein?
Positively regulates expression of some phage genes.  Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes (By similarity).
What are the official names of this protein?
Antitermination protein Q.
What is the protein family that this protein belongs to?
Belongs to the phage antitermination Q type 1 family.
Protein: HIS6_DESDA
Sequence: MLSKRVIPCLDVRNGRLTKGVKFVGNEDIGDPVESARRYYEEGADEIVFYDITASAEARGIFLDVVERVAEQIFIPFSVGGGISSVADMRAVLLAGAEKVSINSAAVKNPRLIGDGADAFGSQAVVVGMDVLAVPESPEIPSGYEIVIHGGRKRMGLDAIAWARCCQELGAGELCVNSIDADGTKDGYELKLTRAIADAVSLPVIASGGAGEPRHMLEAVTGGGASAALIASIVHYGQYSIRQCKEYMAAHGARMRLTW
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATX2L_HUMAN
Sequence: MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE
What is the function of this protein?
Involved in the regulation of stress granule and P-body formation.
What are the official names of this protein?
Ataxin-2-like protein, Ataxin-2 domain protein, Ataxin-2-related protein.
What is the protein family that this protein belongs to?
Belongs to the ataxin-2 family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm. Nucleus speckle. Cytoplasmic granule. Note=Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657). Component of cytoplasmic stress granules (PubMed:23209657). Inhibition of methylation alters nuclear localization (PubMed:25748791). Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791).
Protein: ALR_STUS1
Sequence: MRPLVATVDLTALRHNYLLAKQCAPQRKAFAVVKANAYGHGAPEAVTALREIADGFAVACLEEAEVIRGCAPEARILLLEGCFEPSEYLRAAELGLDIAVQDARQADWLLAADLARPLNVWLKLDSGMHRLGFSVDGLRECHARLKGAAQVGELNLISHFACADERGHALTETQLERYAELLELPFEHCSLANSAAVLTLPQAHMAWIRPGIMLYGATPFAELSARELGLKPVMTLTGALIAVRDVPVGESVGYGASWVAQRPSRIGTVSCGYADGYPRTAPSGTSVVIHGQRVPLAGRVSMDMLAVDLTDLPQAQLGDAVELWGAQMPIDELAQACGTIGYELLTKVTGRVPRRYIG
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: KIME_MOUSE
Sequence: MLSEALLVSAPGKVILHGEHAVVHGKVALAAALNLRTFLLLRPQSNGKVSVNLPNIGIKQVWDVGMLQRLDTSFLEQGDVSVPTLEQLEKLKKMGDLPRDRAGNEGMALLAFLYLYLAICRKQRTLPSLDMVVWSELPPGAGLGSSAAYSVCLAAALLTACEEVSNPLKDGVSVSRWPEEDLKSINKWAFEGERVIHGNPSGVDNAVSTWGGALRFQQGTMSSLKSLPSLQILLTNTKVPRSTKALVAAVRSRLTKFPEIVAPLLTSIDAISLECERVLGEMVAAPVPEQYLVLEELIDMNQHHLNALGVGHNSLDQLCQVTAAHGLHSKLTGAGGGGCGITLLKPGLEQATVEAAKQALTSCGFDCWETSIGAPGVSTHSAAAVGDPVRQALGL
What is the function of this protein?
Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
What are the official names of this protein?
Mevalonate kinase, MK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome.
Protein: CYSNC_RHOBA
Sequence: MSHQSDLIATDIDAYLKQHEQKQLLRFITCGSVDDGKSTLIGRLLYDSKLVYEDELAKVQSDSVRQGSVAGGFDPSLFMDGLKEEREQGITIDVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASSADLAIILIDARHGVLTQTRRHSFIVSLLGIRHVVVAVNKMDIDGVDYSEDRFNEICDDYRSFATRLDLPDLHFIPISALNGDNLVDRSENMPWYTGSTLMNFLETVYIGSDRNLQDFRLPVQLVNRPNLNFRGFCGTIASGIIRKGEEITVLPSRQKSKVKEIVTYDGNLDEAYAPLAVTLTLEDEIDASRGDMIVRSGNLPRSESDVEAMLVWMNEEAMVPGKTYLVKHSTQTVPGNVETLAYKVDVNDLHRMPAPTLELNEIGRVRLSLSAPIHHDPYRRNRTTGAIILVDRITNATVAAGMILDRGTTGSHKSVWDDEVSTDDSSDALSTVTTEERAARFGQKPATVLLTGLTGSGKTSIARAVERKLFDAGRSVAVVDGEFVRRGLSRDLGFSADDRSENLRRSGHLAHTLNDAGLICLASLVAPSDDVRQKVGKLIGEDQFLVVHVATPLDVCRERDTKGQYAKADAGELSNFPGVTAKYDVPTNPDLAVDASTTSIAECADAVVELLKLKGFIK
What is the function of this protein?
APS kinase catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Bifunctional enzyme CysN/CysC.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
Protein: RNH2_GLUOX
Sequence: MPDYALEAAHGGLVVGIDEVGRGPLAGPVVASAVAFTAPPSETLSSLLDDSKKLTARRRMLAYEALMADEQALIGIGAASVAEIERINIAQACYLAMRRALSRLGCTPDLALVDGKHAPKLPCPIKMVIGGDGISLSIAAASIIAKVTRDRLMVRLAVRHDAYGWERNAGYGTAAHMQGLKLRGVTPHHRRGFAPIRNMIEAEAHAA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUB_BREBE
Sequence: MVKSKYLVFISVFSLLFGVFVVGFSHQGVKAEEERPMGTAFYESFDAFDDERWSKAGVWTNGQMFNATWYPEQVTADGLMRLTIAKKTTSARNYKAGELRTNDFYHYGLFEVSMKPAKVEGTVSSFFTYTGEWDWDGDPWDEIDIEFLGKDTTRIQFNYFTNGVGGNEFYYDLGFDASESFNTYAFEWREDSITWYVNGEAVHTATENIPQTPQKIMMNLWPGVGVDGWTGVFDGDNTPVYSYYDWVRYTPLQNYQIHQ
What is the function of this protein?
Hydrolyzes B-glucans containing mixed beta-1,3 and beta-1,4 linkages.
What are the official names of this protein?
Beta-glucanase, 1,3-1,4-beta-D-glucan 4-glucanohydrolase, Endo-beta-1,3-1,4 glucanase, Lichenase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family.
Protein: BIOC_ANOFW
Sequence: MVEKMIDKQLMQKRFSERATTYDRFANVQKKMAHALMKRIVHPPQTILEIGCGTGYLTKLLHDAYPKAELTAVDIAPGMIEKAKQRLGDAPITWLCADIEEAELYEMYDLIISNATFQWLTAPKQTIAKLAKQRNERGQLLFSTFGDRTFHELHTSFAYALAIQQIDEPLRIGPSFPTFSEWLAMHDQARGHEQFEVEYFPSVRDFFLSLRHIGATNSTSGRYCQRPSVFKAMMHEYEQRFSEQGLIRATYHCIFIDIT
What is the function of this protein?
Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM).  It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
What are the official names of this protein?
Malonyl-[acyl-carrier protein] O-methyltransferase, Malonyl-ACP O-methyltransferase, Biotin synthesis protein BioC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: LPLT_SERP5
Sequence: MNPTLPTDSPLLSRSMIAVICAQFLSAFGDNALLFATLALIKQQLYPDWSQPILQMAFVATYIILAPFVGQVADSFAKGRVMMVANGLKLAGALVICFGFNPFLGYTLVGVGAAAYSPAKYGILGEITSGEKLVKANGLMEASTIAAILIGSVAGGILADWHIVAALAVCAVVYAAAVIANLYIPRLPAAHPAVSWTPRAMTQAFFNACVVLWRDGQTRFSLIGTSLFWGAGVTLRFLLVLWVPVALGIADNATPTLLNAMVAVGIVIGAGAAARFVTLETVRRCMPAGILIGVAVAIFALQTTLFNAYALLLIIGVLGGFFVVPLNALLQERGKNSVGAGNAIAVQNLGENTAMLLMLGLYSLAVKVSVPVVGVGIGFGVVFALAISALWLSQRRAK
What is the function of this protein?
Catalyzes the facilitated diffusion of 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) into the cell.
What are the official names of this protein?
Lysophospholipid transporter LplT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LplT (TC 2.A.1.42) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.