PharMolix/UniProtQA huggingface dataset:
Protein: TSAC_PSYIN
Sequence: MLLLLKQSELNDALKILKSQGVIAYPTESVFGLGCDPDCEAAIQKILLLKQRPAYKGLILIAASIEQLEKYADFSLLTAAQLTVIKKTWPGPITWIVPSQKNLSKLISGDFESVAVRVTAHPIVRQICLAFDKPIISTSANLSSLEAALSSQQVNKMFKSNTLLNLVIDAPVSGLSTPTQIFHASTGKRLR
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
What are the official names of this protein?
Threonylcarbamoyl-AMP synthase, TC-AMP synthase, L-threonylcarbamoyladenylate synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaC, tRNA threonylcarbamoyladenosine biosynthesis protein TsaC.
What is the protein family that this protein belongs to?
Belongs to the SUA5 family. TsaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_PROM9
Sequence: MSKLKTRKSAAKRFKATATGKFMRRRAYHNHLLDHKSSKLKRHLSTKAVVDERDADNVKLMIPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL14_BACAH
Sequence: MIQQESRLKVADNSGARELLTIKVLGGSGRKYANIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIKDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: RLMN_METCA
Sequence: MNSAPVPADTETRVNLLDLDREGMEAFFVRLGEKPFRASQLLQWIHQRGVTDFGLMTNLSKTLRSRLEAVSEIRPPELVLEQRSADGTRKWVLQVDAVNRVETVLIPDEGRNTLCVSSQVGCSLECSFCSTARQGFNRNLTTAEIIGQLWVAQHRLDEEQRISNVVLMGMGEPLLNFGNVVAATRLMMDDFAYGLSKRRVTLSTSGIVPALDRLAEVSDISLAVSLHAPDDTLRNELVPINRKYPIRELLAACKRYVGTENRRKVTFEYVMLDGVNDRPEHARALVRLLSHVPSKVNLIPFNPFPNSAYRCSHPETIARFAQTLQDAGLITTTRKTRGRDIDAACGQLVGKVNDRSRRQFRLHLAH
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_METBF
Sequence: MVSKQPRKQRKARYNAPLHVRQKFMGARLSEALSKEYGTRSAAVIAGDTVKVMRGDYKGTEGKVQAVSLQDGTISVDGVISTKVDGTEVPRPIYPSNVMITKLELKDERRASSIKK
What is the function of this protein?
Located at the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MFA2_USTMD
Sequence: MLSIFETVAAAAPVTVAETQQASNNENRGQPGYYCLIA
What is the function of this protein?
Mating pheromone for A2 allele.
What are the official names of this protein?
A2-specific pheromone, Mating factor A2.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: YBQ3_SCHPO
Sequence: MPPIKTAVLGTGVSAFVFHFPFLEALPSKFEIYACLERRATVTQSKARSAYPNILVYTNLDELLADVNIELVVVSLPPNVHSEIVKKALNAGKHVVCEKPFTPTYEEAKELYELAESKSLLLAIYQNRRWDGDFLTAKKIIESGRLGQVVEFESHFDRYRLGRKSGSWKDEPRPGNGMVYGIGSHLIDQAVSLFGTPYSVTAKLEAQRQIPPLEVEDYFRIILHYPAKGNKLPINVILSSTNVSCGCEMRFCIKGTRGSFMKFGFDPQESQLHSGMKPNDHGFGTDRFELYGNLWTVPLDADVKALPEPTKITVPTVQGNYRDFYDAVFEEILKKANEFPIKSDQVLAVEKIMEAAYKSSESSSSIQL
What are the official names of this protein?
Uncharacterized oxidoreductase C115.03.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: HYAL2_HUMAN
Sequence: MRAGPGPTVTLALVLAVSWAMELKPTAPPIFTGRPFVVAWDVPTQDCGPRLKVPLDLNAFDVQASPNEGFVNQNITIFYRDRLGLYPRFDSAGRSVHGGVPQNVSLWAHRKMLQKRVEHYIRTQESAGLAVIDWEDWRPVWVRNWQDKDVYRRLSRQLVASRHPDWPPDRIVKQAQYEFEFAAQQFMLETLRYVKAVRPRHLWGFYLFPDCYNHDYVQNWESYTGRCPDVEVARNDQLAWLWAESTALFPSVYLDETLASSRHGRNFVSFRVQEALRVARTHHANHALPVYVFTRPTYSRRLTGLSEMDLISTIGESAALGAAGVILWGDAGYTTSTETCQYLKDYLTRLLVPYVVNVSWATQYCSRAQCHGHGRCVRRNPSASTFLHLSTNSFRLVPGHAPGEPQLRPVGELSWADIDHLQTHFRCQCYLGWSGEQCQWDHRQAAGGASEAWAGSHLTSLLALAALAFTWTL
What is the function of this protein?
Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides.  Displays very low levels of activity.  Associates with and negatively regulates MST1R.
What are the official names of this protein?
Hyaluronidase-2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2, LuCa-2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 56 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: DDL_MANSM
Sequence: MKPLKEQKIAVLLGGTSAEREVSLTSGDAVLTALRNQGYDAHPIDPKEYPVAQLKEQGFERAFNILHGRGGEDGVIQGVLEQIGLPYTGCGVMTSALTMDKMRTKMLWKGFGLPIADMEIVTRDTVDELNPLEVVERLGLPLMVKPSREGSSVGLTKVNAVEELKNAVDLALTHDDTVLIEEWLSGIEMTVPVLDDQVLPAVQIIPEGEFYDYDAKYISDNTRYICPAPMSEESLQELQKLVKRAYDVVGCRGWSRIDVMTDANGNFRLVEVNTTPGMTSHSLFPKSAATVGYSFEQLVVKILELSA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F6H2_ARATH
Sequence: MNQTLAAQFLTRDQVTNFVVHEGNGVKGLSETGIKVLPDQYIQPFEERLINFHVKEDSDESIPVIDISNLDEKSVSKAVCDAAEEWGFFQVINHGVSMEVLENMKTATHRFFGLPVEEKRKFSREKSLSTNVRFGTSFSPHAEKALEWKDYLSLFFVSEAEASQLWPDSCRSETLEYMNETKPLVKKLLRFLGENLNVKELDKTKESFFMGSTRINLNYYPICPNPELTVGVGRHSDVSSLTILLQDEIGGLHVRSLTTGRWVHVPPISGSLVINIGDAMQIMSNGRYKSVEHRVLANGSYNRISVPIFVSPKPESVIGPLLEVIENGEKPVYKDILYTDYVKHFFRKAHDGKKTIDFANI
What is the function of this protein?
2-oxoglutarate (OG)- and Fe(II)-dependent dioxygenase (2OGD)involved in scopoletin biosynthesis.  Converts feruloyl CoA into 6'-hydroxyferuloyl CoA but has no activity with ferulic acid, feruloylquinic acid, caffeic acid, caffeoyl CoA, p-coumaric acid, cinnamic acid, cinnamoyl CoA or benzoyl CoA.
What are the official names of this protein?
Feruloyl CoA ortho-hydroxylase 2.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RL35_PSEAE
Sequence: MPKMKTKSGAAKRFKKTAGGLKHKHAFKSHILTKMTTKRKRQLRGTSMLNKSDVARVERSLRLR
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: Y096_RICCN
Sequence: MINNIFIKIFLVFLVCMSAIYFGYQYYQNSKPVITIYPDELPTKIKPSIIENNQIAAVHSTIYENLIAKDTNIKTVKLLPDPEKPMSIDSRNQSQSDESFDEISNLIALIEPNNNAKNETDLNIIKLEKGSKDKVSNAKNCKNNESYKVQLGSVKSEAEAMKEGERIKKQFPKILKNVVITTKKVKYDDGKFFYLILAGDYGSLSQAKAVCKKLAYNKQSCVLK
What are the official names of this protein?
Uncharacterized protein RC0096.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: CTL1_XENLA
Sequence: MGCCGSTQNSKRDWRPLEEHSCTDIPWLLLFILFCVGMGFICGFSIATGAASRLVFGYDSYGNICGQKNTKIEGFINSGLDHSNNKYVFFLDPCKLDLVNRKIKSIALCVSECPREELQTLNDVKKFAETNGSALCDYSLTPSQYTTDSRAPSLCPKLPVPKSAPIPFFHRCAPVNISCYAKFAEALITFVSDNSVLHRLISGVMTSKEIIMGLCLLSLVLSMILMVIIRYISRVLVWIITILVVLGSLGGTGVLWWLYADNKKSLNENLPPDQLQVSKDNLQALLVYAIAATVFTVILLLMMLIMRKRVALTIALFNVAGKVFIHLPLLVFQPFWTFFALLLFWVYWVMVLLFLGTAGDPFTNEQGFVEFRINGPLQYMWWYHLVGLIWISEFILACQQMTIAGAVVTYYFTRNKNDLPFTPILASVNRLIRYHLGTVAKGAFIITLVKIPRMILMYIHSQLKGKENACARCMLKSCICCLWCLEKCLAYLNQNAYTATAINSTNFCTSAKDALVILVENALRVAAINTVGDFMLFLGKILIVSCTGLAGIMLLNYQRDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTKYNDGSPGKEFYMDKVLMEFVEDSRRALKEPGSTAEGRELKPMASGTSTA
What are the official names of this protein?
Choline transporter-like protein 1, Solute carrier family 44 member 1.
What is the protein family that this protein belongs to?
Belongs to the CTL (choline transporter-like) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NAMA_HALH5
Sequence: MEHKLFSSYVVKGVTLKNRIVMSPMCMYSSDQKDGKIRPFHISHYESRAAGQVGLIIVEATAVTPQGRISPYDLGIWSDDHISGLTETVERIHAHGAKAAIQLAHAGRKAELDGPIIAPSAISYDKMKTPDAMTEEQISETIEAFKLGALRAKKAGFDIIEIHGAHGYLINEFLSPLTNKRTDAYGGSLENRYRLLREIISEIQTVWDGPLFVRISAAEYAEGGNELSDFITLAKWMKKQGIDLIDCSSGAVVPAPIPVYPGYQVPLAEAIRHEANIATGAVGLITSGIQAEEILQNERADLIFVARELLRNPYWPREAALELGTTISGPSQYDRAWL
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: KCY_LISMO
Sequence: MTKKICIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIALKNNIAYEDEKAIAALLQKTVIRFEPGEVQQVFVGSENVTEVIRSIEVTNHVSIVAAHPSIREALQERQQVFATEGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRYKENMAKGFTGDLDQLKKEIEERDHLDYTRTHSPLKKADDAIEVDTTSMSIDQVANKILSLAELKINN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMC_YERP3
Sequence: MHCAQYAAGRCRSCQWLDKPYPQQLADKQHHLESLLAGHAVTQWLALVFGRESAFRNKAKMVVSGSVERPLLGMLHRDGTPVDLCACPLYPPSFEPVFTVLKTFIARAGLTPYNVARKRGELKFLLLTESTYNGELMLRFVLRSETKLAQLTAALPWLQQQLPQLAVISANIQPVHMAILEGEREIPLTEQQALPERFNQVPLYIRPQSFFQTNPPVAASLYATARQWVQEHEVHSMWDLFCGVGGFGLHCAGPETQLTGIEISAEAIACARQSAEQLGLKNVSFAALDSTRFATAEAQIPELVLVNPPRRGIGRELCDYLSQMAPKFILYSSCNAETMAKDISLLAGYHIERVQLFDMFPHTSHYEVLTLLALRR
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: RL27_STRPJ
Sequence: MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: BCL7B_HUMAN
Sequence: MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES
What is the function of this protein?
Positive regulator of apoptosis.  Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1 (PubMed:25569233).  Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation (PubMed:25569233).  May play a role in lung tumor development or progression (By similarity).
What are the official names of this protein?
B-cell CLL/lymphoma 7 protein family member B.
What is the protein family that this protein belongs to?
Belongs to the BCL7 family.
Protein: HUTP_HALH5
Sequence: MSKHKSHRIGQLAILLAVSEEPGIVEASILSSDYQSCIGRVGSMESNKIVAAIETAAKKNGFIREGVYREAHALYHAIIEALHGVTRGQVQLGSFQRTVGLRFAIVRGKPYKEEAEGEWIAVALYGTIGAPIKGQEHETIGLGINHI
What is the function of this protein?
Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.
What are the official names of this protein?
Hut operon positive regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the HutP family.
Protein: RPB2_ASFWA
Sequence: MEPLRPQITYGPIETVDNEELTEADMLSFISAAVNSTGLIGYNIKSFDDLMDNGIPQIVKQMFNVDITYKDQRDHTEIDKLRESVQIQFNFTDVNIERPQHRNYSQGNKINLLPNKARLCGLSYSGPVNLAAEVILTAHYSNGRQEVKRASIPPFQVSTFPIMRGSNRCHTHHLSKTAKKEIGEDPNEPGGYFIARGGEWVVDLLENIRFNTLHIHYHTMQQGNNEIIRGEFISQPGGAFENSSQIIIRYMTTGAITIEINSTKFSKLRIPWYLIFRMFGMTGDDSIIEQVVFDLESNSLVNTFMIEILEKSIHVLDPIFQPVQHELNREKIIQFLSEKVSKFVSNPSAYKSDENAVQYLNERQLTILDKILLPHMGQTADTRVRKLRFLGLLIHKILLVIMNVFPPTDRDSYRTKRVHGSGVSLAKAFKAIFNTSVIAPIINGFKELLKQTAFEELTQRNIIEAFSAALSKNTASDLNRSMEQSIISGNKTIMVRQRPIVNRVSTQSLERKNLLNTISALRTVNTHNTTNASKQTERADMMRRVHASYPGYICVAQSADTGEKVGMSKQLAITANVCTAGEVLSLKQRLLSDPAIQQLADVSNKDIVRKGLARVFINGEWIGCCTNAFELAQRYRMLRREGKIVHPHTTIYWDSMVDEVEFWLDVGRLTRPLLIVDNNIEKYNQACYKAAEARKKGDKDWEKHKIPFVQNTRFTSQMAKDILAGTLTLEDLVAQGICEFITPEEAENCLVAFSIIELRKHKHDVTRRFTHVDVPQAILGLAALVSPYANCTQPARVTYETNQGRQTGGWYCFSWPYRVDMNRFFQFYNEMPLVKTIAHNYVIPNGLNTIVAYMIYGGYNQEDSVIVSQSFIDRGGFAGTFYREEKVELESDIESFGKPDPLITKNLKPGANYEKLVDGFVPVGTVVKKGDIIIGKVAKIRGEKDELNKYIDRSVMYGFDEPAVVDAVMRPHGPNDEIFGLMRLRYERNLNIGDKMSSRSGNKGIAALALPTSDMPFTEDGLQPDLIVNPHSHPSRMTNGQMIETTVGLANALQGVVTDGTAFLPINVQLLSERLAQEGLRFNGCQKMFNGQTGEYFDAAIFIGPTYHQRLQKFVLDDRYAVASYGPTDALTGQPLDGKRSHGGLRLGEMEHWVLTAQGAMQTIIEKSHDDSDGCISYVCRNCGEPAIYNASHPIYKCMNCDVQADIGMVDSRRSSIVFQHEMRAANVNITSVLSPRVFQPA
What is the function of this protein?
Catalytic component of the DNA-directed RNA polymerase (RNAP) that catalyzes the transcription in the cytoplasm of viral DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity).  Forms the polymerase active center together with RPB1 (By similarity).  Part of the core element with the central large cleft, the clamp element that moves to open and close the cleft and the jaws that are thought to grab the incoming DNA template (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase RPB2 homolog, RPB2 homolog.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion. Note=Found in association with viral nucleoid.
Protein: HFQ_THEPX
Sequence: MASSKAAINLQDIFLNQVRKEHVPVTVYLINGFQLKGLVKGFDNFTVVLESENKQQLLIYKHAISTITPQKPVIFSASDKDEKREE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: PPO1_PHYPO
Sequence: MALTNAQILAVIDSWEETVGQFPVITHHVPLGGGLQGTLHCYEIPLAAPYGVGFAKNGPTRWQYKRTINQVVHRWGSHTVPFLLEPDNINGKTCTASHLCHNTRCHNPLHLCWESLDDNKGRNWCPGPNGGCVHAVVCLRQGPLYGPGATVAGPQQRGSHFVV
What is the function of this protein?
Mediates the homing of a group I intron in the ribosomal DNA.  Makes a four-base staggered cut in its ribosomal DNA target sequence.
What are the official names of this protein?
Intron-encoded endonuclease I-PpoI, I-Ppo.
Protein: DEOD_ACTPL
Sequence: MATPHINAPEGAFADVVLMPGDPLRAKYIAETFLEDAVQVTDVRNMFGYTGTYKGRRISVMGHGMGIPSCSIYAKELITEYGVKKIIRVGSCGAVRQDVKVRDVIIGSGACTDSKVNRIRFRDNDFAAISDFDMTLAAVQAAKQKGIAARVGNLFSADLFYTPDVEMFDVMEKYGILGVEMEAAGIYAVAAEYGAKALAICTVSDHIRTGEQTSSEERQLTFNDMITIALESVLIGDKAE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: IF1_NEIMF
Sequence: MAKEDTIQMQGEILETLPNATFKVKLENDHIVLGHISGKMRMHYIRISPGDKVTVELTPYDLTRARIVFRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_BRUME
Sequence: MGLSPVNIFKPFGLGRAKAVIAAVSGGSDSLGLLFLLKDYLSTLESPPVLIAVTVDHKLRAESALEAENVGLLCQKHGIMHCVLSWDDPKPAHGLAAAARTARYRLLVQAARDAGAGFIVTGHTENDQIETFLMRKARSGHCEARGLAAMSPRSLLEGSVELARPLLTVSRQALRDELTRRGIAWVDDPSNANIDYERPRVRLGVAAEADGQEVLEQIAQAGAARERNNAALVEALADPATLGVDAAGMMFLNADCYAALSPGARQLFSGLLASIAGGRRFLPGDGERRRIERMLSGQDAPRRLTVFGALIERGEKGAPHRFRRERRNLPKLDLVPGQHIVWDGRFCFFNSGGRSFEIAPPGRQELIDFLKNSGRDIESRRCEALLISPALYEGGKLAFVPFLPGAEWPQGVHIERHFAIFDHVLPGHDFALAQAVEARLGRACAEIS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRR40_ARATH
Sequence: MYPSCSLLQRLVWFPFLALVATQLLFIRNVSSLNLTNEYLHHKCLVSEGKYKPGSKYEYILNDHIRFLAAGNFRSGSMHMTSGLKPNAVTILYQCRGDSYNSKCRSCYAAGISGLRRRCPRNKGGIIWFDQCFVEITSISVIDFNISKINYENNFPLHNPNRVSGDIKSFNNETMALLKELALKANNKDNMDNGKMALYASGEKRVGTKKVYAMVQCMRDLVKPKMCKECLESIIKEFPECCDGKQGGRILGTSCDFRYELYPFLRTSDSKTV
What are the official names of this protein?
Putative cysteine-rich repeat secretory protein 40.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL25_RICCN
Sequence: MSEILELEAESRTEFGTGAARALRRAGRVPAIIYGAGKTPVSISLEEKEITKYYRKPAFISQLINLTIDKKKYKVLPKAVELHPVTDIVRHVDFVFLEEKTQKMEVPVVYEGKERALGVKRGGYFNIVKRRVTLLCDVNNIPRNVTIDVTNMPMATSLKSSKIELPKGCSFVTNKEFVLATIIGRRGAKTEAEGEQQAAEAGK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: Y279_CLAM3
Sequence: MLLRTVILFALAAVAEIGGAWLVWQAVREGRPWWWAGLGVMALGAYGFIASLQADASFGRILAAYGGVFVAGSLVWGAVVDGYRPDRWDVIGAVVCLLGVAVIMFGPRGQGA
What are the official names of this protein?
UPF0060 membrane protein CMM_0279.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IAA2_STROI
Sequence: SDASEPAPACVVMYESWRYTTAANNCADTVSVSVAYQDGATGPCATLPPGAVTTVGEGYLGEHGHPDHLALCPSS
What is the function of this protein?
Inhibits mammalian alpha-amylases specifically but has no action on plant and microbial alpha-amylases.
What are the official names of this protein?
Alpha-amylase inhibitor Paim-2, Pig pancreatic alpha-amylase inhibitor of microbes II, Paim II.
Protein: GLUA_COREF
Sequence: MIKMTGVQKFFDDFQALTDINLEVPAGQVVVVLGPSGSGKSTLCRTINRLETIEEGTIEIDGKLLPEEGKDLAKIRADVGMVFQSFNLFPHLTIKDNVTLGPMKVRKMKKSEANEVAMKLLERVGIANQAEKYPAQLSGGQQQRVAIARALAMNPKIMLFDEPTSALDPEMVNEVLDVMASLAKEGMTMVCVTHEMGFARRAADRVLFMSDGAIVEDSDPETFFTNPQTDRAKDFLGKILAH
What is the function of this protein?
Part of the ABC transporter complex GluABCD involved in glutamate uptake.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Glutamate transport ATP-binding protein GluA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GATA_COREF
Sequence: MSNKYLVEGSTSELTTKTAAELAGLIHSREVTSREVTQAHLDRINEVDGEIHAFLHVGEEAALAAADAVDKALDAGEAPASALAGVPLALKDALVTTDAPTTAASKILEGYMSPYDATVTRKLREAGIPILGKTNMDEFAMGSSTENSAYGATRNPWDLERTPGGSGGGSSAALASGEAPLAIGTDTGGSIRQPAALTNTVGVKPTYGTVSRYGLIACASSLDQVGPTARTVLDTALLHEVIAGHDMFDATSVDKPVAPVVAAAREGANGDLKGVRVGVVNQFDREGYQDGVLEAFHASVEQMRSQGAEIVEVDCPHFDDALGAYYLILPCEVSSNLARFDGMRYGLRSGDDGTRSADEVMALTRAEGFGPEVKRRIILGTYALSVGYYDAYYLQAQRVRTLIAQDFTRAFEQVDVLVSPTTPSTAFKLGDKITDPLEMYNFDLCTLPLNLAGLSGMSLPSGLASDTGLPTGLQIMAPAFQDDRLYRVGAAFEAGRK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NSP4_ROTRF
Sequence: MEKLTDLNYTSSVITLMNSTLHTILEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIHDKLMIRAVDEIDMTKEINQKNVRTLEEWENGKNPYEPKEVTAAM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.