PharMolix/UniProtQA huggingface dataset:
Protein: FDB2_GIBM7
Sequence: MARLEDPTALTQLPDESARVRYTSSELQDYFETLKFPQRFLDLGNSVLKDPSLARTKENGLPLLQAITRYHTCNVPFENLVLHYDPHKIVTLDPAELYTKIVTRRRGGRCMENNIFLGTALRSLGYEVRNCGGRVSRAMSPYPEVRKNQSATYDGWNHMLLLVFLGDEWYGVDVGMGSMGPNLPFPLQDGFESLSIAPREIRIQKRSISETHATGPSHATKMWCYDVCYNPAESKKTWTPVYCFTETEFLPQDYEVMSWFTSTNPRSFFTRYITCTKMIMDEDKEVIIGNLTLFKDTVRETIGSDRKVVKKFETEEERIKGLVEIFDVNLTEEEKNSLPQEKRLA
What is the function of this protein?
N-malonyltransferase; part of the Fusarium detoxification of benzoxazolinone cluster 2 (FDB2) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the FDB1 cluster gamma-lactamase MBL1 to aminophenols (PubMed:26808652, PubMed:12788712).  MBL1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26808652, PubMed:12788712).  The FDB2 cluster N-malonyltransferase FDB2/NAT1 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:19302487, PubMed:12788712).  FDB2/NAT1 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:19302487, PubMed:12788712).  The duplicated dienlactone hydrolases DLH1 and DLH2 may provide redundant function for hydrolyzing the lactone moiety in the BOA molecule (Probable).  The roles of the amidases an other enzymes encoded by the 2 FDB clusters have not been identified so far (Probable).
What are the official names of this protein?
N-malonyltransferase FDB2, Fusarium detoxification of benzoxazolinone cluster 2 protein NAT1, FDB2 cluster protein NAT1.
What is the protein family that this protein belongs to?
Belongs to the arylamine N-acetyltransferase family.
Protein: JMJD8_HUMAN
Sequence: MAPASRLLALWALAAVALPGSGAEGDGGWRPGGPGAVAEEERCTVERRADLTYAEFVQQYAFVRPVILQGLTDNSRFRALCSRDRLLASFGDRVVRLSTANTYSYHKVDLPFQEYVEQLLHPQDPTSLGNDTLYFFGDNNFTEWASLFRHYSPPPFGLLGTAPAYSFGIAGAGSGVPFHWHGPGYSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLRDTYPALPPSARPLECTIRAGEVLYFPDRWWHATLNLDTSVFISTFLG
What is the function of this protein?
Functions as a positive regulator of TNF-induced NF-kappa-B signaling (PubMed:27671354).  Regulates angiogenesis and cellular metabolism through interaction with PKM (PubMed:27199445).
What are the official names of this protein?
JmjC domain-containing protein 8, Jumonji domain-containing protein 8.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Cytoplasm.
Protein: YBG3_NEUCR
Sequence: MKFSGLILGALALVSGAIAVDIQKSVIITYKENTPDSVIQQDKKAILDDGGVITHEYTLMKGFSAKVNAKTLESVSASSESYATIEEDKVVSTL
What are the official names of this protein?
Uncharacterized protein B24G3.190.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I9 family.
Protein: RS12_CORJK
Sequence: MPTIQQLVRKGRHDKSTKVATAALKGSPQRRGVCTRVYTTTPKKPNSALRKVARVRLTSGIEVSAYIPGEGHNLQEHSMVLVRGGRVRDLPGVRYKIVRGSLDTQGVKDRKQARSRYGAKKEK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RUVC_BURL3
Sequence: MRILGIDPGLRVTGFGIIDVSGHRLAYVASGVIRTPTADLATRLGTIFQGVSTIVREHAPDQSAIEKVFVNVNPQSTLLLGQARGAAICGLVAGGLPVAEYTALQLKQAVVGYGRATKTQMQEMVTRLLNLSGQPGSDAADALGMAICHAHGGNTLSTLGGLAPALAKKGLRVRRGRLVG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: CYB_YEAST
Sequence: MAFRKSNVYLSLVNSYIIDSPQPSSINYWWNMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHNGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGHPDNYIPGNPLVTPASIVPEWYLLPFYAILRSIPDKLLGVITMFAAILVLLVLPFTDRSVVRGNTFKVLSKFFFFIFVFNFVLLGQIGACHVEVPYVLMGQIATFIYFAYFLIIVPVISTIENVLFYIGRVNK
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (Probable).  Cytochrome b is a catalytic core subunit containing 2 b-type hemes BL and BH topographically segregated in the quinone reduction (Qi) and quinol oxidation (Q0) sites on opposite sides of the membrane (PubMed:18390544).
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit CYTB, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Cytochrome b-c1 complex subunit CYTB, Ubiquinol-cytochrome c oxidoreductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS8_ANAPZ
Sequence: MSLSDPIADFLTRLRNGQAGMNKVVYVPCSKVVMAVLRILVEEGYIESFTEEVRGDSGIKVLKVFLKYFNSAAAIRKIVRVSRPGKRVYSSADKMPRFYNALGIYIVSTSKGIMLDSHARNAGVGGEILCGVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ERP29_BOVIN
Sequence: MAAAIPRAASLSPLFPLLFLLSAPQDSSGLHTKGALPLDTITFYKVIPKSKFVLVKFDTQYPYGEKQDEFKRLAENSASSDDLLVAEVGISDYGDKLNMELSEKYKLDKENYPIFYLFQDGDFENPVLYSGAVKVGAIQRWLKGHGIYLGMPGCLPAYDTLAGEFIRASGVEARQSLLKQGQDNLASVKETDKKWAEQYLKIMGKILDQGEDFPASEMTRITKLIEKNKMSDGKKEELQKSLNILTAFQKKGGEKEEL
What is the function of this protein?
Does not seem to be a disulfide isomerase.  Plays an important role in the processing of secretory proteins within the ER (By similarity).
What are the official names of this protein?
Endoplasmic reticulum resident protein 29, ERp29.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Melanosome.
Protein: UNG_YERPY
Sequence: MSPSLTWHDVIGQEKEQPYFKDTLAYVAAERRAGKTIYPPQKDIFNAFRLTELDQVKVVILGQDPYHGPNQAHGLSFSVLPGVPAPPSLGNIYKELVTDIPGFQRPNHGFLQSWAEQGVLLLNTVLTVEAGKAHSHANLGWETFTDRVIAALNEHREGVIFMLWGSHAQKKGRIINTERHYILKAPHPSPLSAHRGFLGCKHFSQANQLLQQQNQQPIDWQPKLPAVE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TIG_MYCPN
Sequence: MKQYKLVNTTQKEKTLCLEIAIDTKLWKETQQKQTQDLTKNMKIKGFRKGKVPPTLAKDYLDRAELLQRSAQAVIDAIFQPLQQEAVIADNENVIEDFPTIDFKTINENDCVILFDFDLVPQFEPPDYKHIKDLSPIVPLKDEEFNKELHNIEKNKGKLVDVSDKALANNDIAVIDFVGKVDGKVLESATAKQYELTIGSNSFIDGFESGLIGMKVGDKRQLKLKFPKDYHAEELKGKPVEFDIELKAIKQLEITPMDETNFKEYLPAQYQGFNSLKEFKTYFHKLVSAKKLEITLQENSVKIRQFFLANTTLPYIPDSLIKLESDRLLRAQKDQAEQYKIPFERLLAASKLSLEQLQQRNIKEARDNVTFALVMKRIADVEKIKVDNKKIHSEIESIIDVEYPFVNAELKKQMFHNMEQQKDFVESIILNRLTTTKIIEYSTH
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase (By similarity).
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: OM25_PASMU
Sequence: MKKAVKVTALSLALAFTSSLAMATENIAFISGDYLFQNHPDRKMVAEKLESEFKARVEKLTANKKSIDEKIAASQKKVEAKVAALQKDAPKLRSADIKKREEEINKLGNSEQEAINKLVTAHDEEVSKYQDDYAKREREETAKLVDSIQNAVNTVAREKNYTLVLNEGAVVFAADAKNITEDVLKVIPATQAK
What are the official names of this protein?
Outer membrane p25, p28.
What is the protein family that this protein belongs to?
Belongs to the Skp family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: GT6_ORYSJ
Sequence: MAASETAPFGVSAASKGGGGVAGARAQHGQLAVAGRVHDALVFAAGAVAAVLVLLATASFLSPMPVTNLVAFRSLPVSVASTSAASAAIDADVGVRGGPGAAGRTFYDDSRVSYAVEVGRRGGITGWDARRAAWMRLRYPRGLNATAAGRERVVMVSGSQAPPCRGEGGDHLLFRFLKNKVDYCRLHGVELLYNNALLQPRMLAYWAKIPAVRAAMLAHPDAEWVWWVDADAVFTDMDFSLPLHKYKDHNLVVYGWNKEVYGERSWVGLNAGVFLIRNCQWSLDFMDAWARMGPASPEYARWGSVLHDTLRGKSDKESDDQSALVYLLSEHEEKWGAKTYLEKGYFFQGYWVEVVDRLDDIAARYEAAERRPSAAAAHLRRRHAEREHERYAAARNAAVRGAVPGPAGGGQSGWRRPFVTHFTGCQPCGGEPNKIYSKKSCADGMNRALNFADDQVLRNYGYRHKDPLSDEVRPLPFDYPAAR
What is the function of this protein?
Probable glycosyltransferase that may be involved in the biosynthesis of xyloglucan.
What are the official names of this protein?
Probable glycosyltransferase 6, OsGT6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 34 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: SETD3_PLEMO
Sequence: MGKKSRVKTQKSGTGATATVSPKEILNLTSELLQKCSSPAPGPGKEWEEYVQIRTLVEKIRKKQKGLSVTFDGKREDYFPDLMKWASENGASVEGFEMVNFKEEGFGLRATRDIKAEELFLWVPRKLLMTVESAKNSVLGPLYSQDRILQAMGNIALAFHLLCERASPNSFWQPYIQTLPSEYDTPLYFEEDEVRYLQSTQAIHDVFSQYKNTARQYAYFYKVIQTHPHANKLPLKDSFTYEDYRWAVSSVMTRQNQIPTEDGSRVTLALIPLWDMCNHTNGLITTGYNLEDDRCECVALQDFRAGEQIYIFYGTRSNAEFVIHSGFFFDNNSHDRVKIKLGVSKSDRLYAMKAEVLARAGIPTSSVFALHFTEPPISAQLLAFLRVFCMTEEELKEHLLGDNAIDRIFTLGNSEFPVSWDNEVKLWTFLEDRASLLLKTYKTTIEEDKSVLKNQDLSVRAKMAIKLRLGEKEILEKAVKSAAGNREYYRQQMEEKAPLPKYEESNLGLLESSVGDSRLPLVLRNLEEEAGVQDALNIREAISKAKTTENGLVNGENSIPNGTRSENENLNQEGSKRAVEDAKGSSSDSTDEVKE
What is the function of this protein?
Protein-histidine N-methyltransferase that specifically mediates 3-methylhistidine (tele-methylhistidine) methylation of actin at 'His-73'.  Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery.  Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin.
What are the official names of this protein?
Actin-histidine N-methyltransferase, Protein-L-histidine N-tele-methyltransferase, SET domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD3 actin-histidine methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes mainly in the cytoplasm.
Protein: KDSB_VIBVU
Sequence: MSFTVVIPARYQSTRLPGKPLADIAGKPMVQWVYEQAIQAGAQDVIIATDDQRVADAVAVFGGKVCMTSPNHESGTERLAEVVQLMGIADDHIVVNVQGDEPLIPPSIIRQVAENLAASSAPMATLGVAITSEEEVFNPNAVKVVTDKEGYALYFSRATIPWDRDAFARGEVLTEHSLMRHIGIYAYRAGFINTYVNWQPSSLEKIECLEQLRVLWYGEKIHVELAKEAPPAGVDTPEDLELVRELIAAKS
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_HELPS
Sequence: MAKRCALTFKGPMVGNHVSHANNKNKRRLLPNLRSIKIQLDDGTTKRIKVAASTLRTMRKGA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NSP12_RDVF
Sequence: MFKSGSGSLKRSGSISSVKSFSGDSEKGLPPISRGSVSITSQNYEPLIVPANSSSFAAASDFVPEKTKSEGNLKNKSSVITGNFESSGPTNAHYNQNADGDRLVENLLLKEIAKGRGPSTSDARHTATDSRLSQEVKQPFSEENAGGNDLNTGRGSHGTGDGIEQYHKSDCEERMSAYHKRVVDTFFKYFEYSAEDGHSTLYSDVAFLFGCGDLDLLVMSRYQEVMTLRARSAIYGIFCYLQALTAYLTYLGAKVGQVIMLDEELEKYEIRLDVAQDDDPIVFQITTGVFTSGVAHDLRKLTQILEAFSLER
What is the function of this protein?
Constituent of viral factories.
What are the official names of this protein?
Non-structural protein 12A, Pns12A.
What is the protein family that this protein belongs to?
Belongs to the phytoreovirus non-structural protein Pns12A family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=Constituent of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: HFQ_SALDC
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CO039_HUMAN
Sequence: MAEKRPLRTLGPVMYGKLPRLETDSGLEHSLPHSVGNQDPCTYKGSYFSCPMAGTPKAESEQLASWTPYPPLYSTGMAGPPLQADNLLTNCLFYRSPAEGPEKMQDSSPVELLPFSPQAHSYPGPPLAAPKPVYRNPLCYGLSTCLGEGAVKRPLDVDWTLATGPLLPSADPPCSLAPAPSKGQTLDGTFLRGVPAEGSSKDSSGSFSPCQPFLEKYQTIHSTGFLASRYTGPYPRNSKQAMSEGPSSPWTQLAQPLGPPCQDTGPTHYPPPHHPPPHPPQALPCPPACRHPEKQGSYSPALPLQPLGGHKGTGYQAGGLGSPYLRQQAAQAPYIPPLGLDAYPYPSAPLPAPSPGLKLEPPLTPRCPLDFAPQTLSFPYARDDLSLYGASPGLGGTPPSQNNVRAVPQPGAFQRACQPLPASQPCSEPVRPAQEAEEKTWLPSCRKEKLQPRLSEHSGPPIVIRDSPVPCTPPALPPCARECQSLPQKEGARPPSSPPMPVIDNVFSLAPYRDYLDVPAPEATTEPDSATAEPDSAPATSEGQDKGCRGTLPAQEGPSGSKPLRGSLKEEVALDLSVRKPTAEASPVKASRSVEHAKPTAAMDVPDVGNMVSDLPGLKKIDTEAPGLPGVPVTTDAMPRTNFHSSVAFMFRKFKILRPAPLPAAVVPSTPTSAPAPTQPAPTPTSGPIGLRILAQQPLSVTCFSLALPSPPAVAVASPAPAPAPSPAPARAQAPASARDPAPAPAPVAGPAPASTSAPGDSLEQHFTGLHASLCDAISGSVAHSPPEKLREWLETAGPWGQAAWQDCQGVQGLLAKLLSQLQRFDRTHRCPFPHVVRAGAIFVPIHLVKERLFPRLPPASVDHVLQEHRVELRPTTLSEERALRELALPGCTSRMLKLLALRQLPDIYPDLLGLQWRDCVRRQLGDFDTEAGAVSSSEPTVARGEPESLALAQKSPAPKVRKPGRKPPTPGPEKAEAAAGEESCGASPTPATSASPPGPTLKARFRSLLETAWLNGLALPTWGHKSSRPDQPSPCPQLLDSQSHHL
What are the official names of this protein?
Uncharacterized protein C15orf39.
Protein: RL4_VESOH
Sequence: MELKVLNISLNSLNTVEVDDTIFARDFNQALVHQVTTAYMSGSRQGSKAQKNRSAVSGGGKRPWAQKGTGRARAGTTRGPIWRSGGVTFATQPRSYAQKVNKKMYKGAISIIFSELVRSERLKVVKEFDIKEVKTKNMIALLKVLNVKDALLMTDELDENLYLSSRNLYHVGVCDTQSIDPVSLIGYDNVVVTELALKKIEVML
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RS14Z_ALKMQ
Sequence: MAKKSLKIKQARTQKYSTREYSRCKICGRPHAYLRKFGVCRICFRELAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SRP14_SCHPO
Sequence: MLLSNEEFLKKLTDLLQTHQSKGTGSVYLSQKCNPVDEGEGSSASVLIRAKSGAAEKISTVVELDYFTDFFQSYAEVCKGQIVGLKKRDRKKTKKNKKKTTSSGHT
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
What are the official names of this protein?
Signal recognition particle subunit srp14, Signal recognition particle 14 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SRP14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMP2_HETSP
Sequence: MSRRLILILVLVAMLVKTMAGMESKWVETTYEIKKRSGTSEKERESERLLGVVNPLIKCFRSPCPGRRAISEQT
What is the function of this protein?
Possesses antimicrobial activity against both Gram-negative and Gram-positive bacteria, as well as against the fungus C. tropicalis.  Also possesses a relatively high hemolytic activity.
What are the official names of this protein?
Antimicrobial peptide HsAp2.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Medium-length antimicrobial peptide (group 3) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: YQ66_SCHPO
Sequence: MSHLFILSCSVYDFSSILLHQYFTQFFVLRYASPSMHLDWRFPSLRIHSYPKDQSTHAWKMHCMPTEIIAYQPIPVFQRLLHSNDIYFPYFQTRYTTLIMFNTVCSSSPNPVFTLTKVIARKKGKHWIGSPCHSAESS
What are the official names of this protein?
Uncharacterized protein C191.06.
Protein: PSBI_SOYBN
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CAIE_SALA4
Sequence: MSYYAFEGLIPVVHPDAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLILEAGSNLQDGCIMHGYCDTDTIVHENGHIGHGAILHGCVVGRDALVGMNSVIMDGAMIGEESIVAAMSFVKAGFQGEARQLLVGSPARVLRQVTDQELHWKRLNTKEYQDLAIRCRTGLSETKPLTQVEENRPRLKGTTDVKPKSAQ
What is the function of this protein?
Overproduction of CaiE stimulates the activity of CaiB and CaiD.
What are the official names of this protein?
Carnitine operon protein CaiE.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
Protein: AMELY_HUMAN
Sequence: MGTWILFACLVGAAFAMPLPPHPGHPGYINFSYENSHSQAINVDRIALVLTPLKWYQSMIRPPYSSYGYEPMGGWLHHQIIPVVSQQHPLTHTLQSHHHIPVVPAQQPRVRQQALMPVPGQQSMTPTQHHQPNLPLPAQQPFQPQPVQPQPHQPMQPQPPVQPMQPLLPQPPLPPMFPLRPLPPILPDLHLEAWPATDKTKQEEVD
What is the function of this protein?
Plays a role in biomineralization.  Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development.  Thought to play a major role in the structural organization and mineralization of developing enamel.
What are the official names of this protein?
Amelogenin, Y isoform.
What is the protein family that this protein belongs to?
Belongs to the amelogenin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: RUTC_METPB
Sequence: MPKTVVIPPGTGKPLAPYVPGTLADGVLYVSGTLPLDAEANVVHEGDAGAQTRHVLETIKSVVEAAGGSMDDVTFNHIFLKDWADYGAINAVYAEYFPGEKPARYCIQCGLVKPTALVEIASVAHLGKPA
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: DEFB2_MOUSE
Sequence: MRTLCSLLLICCLLFSYTTPAVGSLKSIGYEAELDHCHTNGGYCVRAICPPSARRPGSCFPEKNPCCKYMK
What is the function of this protein?
Has bactericidal activity.
What are the official names of this protein?
Beta-defensin 2, BD-2, mBD-2, Defensin, beta 2.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MATP_SHIF8
Sequence: MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE
What is the function of this protein?
Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle.  Prevents early segregation of duplicated Ter macrodomains during cell division.  Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.
What are the official names of this protein?
Macrodomain Ter protein.
What is the protein family that this protein belongs to?
Belongs to the MatP family.
What are the subcellular locations of this protein?
Cytoplasm.