PharMolix/UniProtQA huggingface dataset:
Protein: TGT_SHEB9
Sequence: MKFELDTTDGRARRGRLIFDRGTVETPAFMPVGTYGTVKGMTPEEVRATGADILLGNTFHLWLRPGEEIMRKHGDLHDFMNWQRPILTDSGGFQVFSLGDIRKITEEGVHFRSPINGEKIFLDPEKSMQIQDALGSDVVMIFDECTPYPATEDEARKSMQMSLRWARRSRDEFDRLENPNSLFGIIQGGVYEDLRDESLKGLVDIGFDGYAVGGLAVGEPKADMHRILEHICPQIPADKPRYLMGVGKPEDLVEGVRRGVDMFDCVMPTRNARNGHLFTSEGVIKIRNARHRDDTSPLDTKCDCYTCKNYSRAYLYHLDRCNEILGARLNTIHNLRYYQMLMEGLRGAIETGTLDAFVADFYTSQGREVPELVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: YOJ4_CAEEL
Sequence: MLEDKGELSIKEVLKCLPISEKSPANWAAWCFGLILVVLILIVTGYMFVVYLRSQRKKNQLADETGGIEIENSIRDPVVINNSLASRSCSENKVKKQSPESTEQDDFSKTTVDETIKEKSEKQPKTCAQKPKVPIPKASTPKTEKLVSKEPSTEELSVKNSLTDLKNEATKMANTSSSANRTGEISVEIVSPKPTTAVQASTPEKPMSSAESAMESSIGSDISTYIVSSKRSEVNNYNMIEAGRTPPMSFSESYAQTAIPTANTPPTVVHVSKPSSETSVSIPPSSAVKK
What are the official names of this protein?
Uncharacterized protein ZK353.4.
Protein: GPAT1_RAT
Sequence: MEESSVTIGTIDVSYLPNSSEYSLGRCKHTNEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSITDNVLNSSRVQEAIAEVAAELNPDGSAQQQSKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDILYRALLHGHIVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLEGQSQKPVSAPLSLEQALLPAILPSRPDAAAAEHEDMSSNESRNAADEAFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSIYAVQNKRGSGGSAGGLGNLISQEQLVRKAASLCYLLSNEGTISLPCQTFYQVCQETVGKFIQYGILTVAEQDDQEDVSPGLAEQQWNKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQAKEHQQFITFLQRLLGPLLEAYSSAAIFVHTFRGPVPESEYLQKLHRYLLTRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRASVLELSTTFLPQGSRQKLLEYILSFVVL
What is the function of this protein?
Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase 1, mitochondrial, GPAT-1.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein.
Protein: GSPJ_ECOLI
Sequence: MINRQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKEIQQFNQLQRTITILDNDLLQLVARRNRSTDKIMVLGEEAIFTTQSRDPLAPLSEAQTLLTVHWYLRNHTLYRAVRTSVDGRKDQPAQAMLEHVESFLLESNSGESQELPLSVTLHLQTQQYGGLQRRFALPEQLAREESPAQTQAGNNNHE
What is the function of this protein?
Component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Part of the pseudopilus tip complex that is critical for the recognition and binding of secretion substrates.
What are the official names of this protein?
Type II secretion system protein J, T2SS protein J, Putative general secretion pathway protein J.
What is the protein family that this protein belongs to?
Belongs to the GSP J family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YCJF_SHIBS
Sequence: MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDEAPEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQQAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREICRSAAESTLMIAVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
What are the official names of this protein?
UPF0283 membrane protein YcjF.
What is the protein family that this protein belongs to?
Belongs to the UPF0283 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21_HUMAN
Sequence: MTNTKGKRRGTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAVGIVVNKQVKGKILAKRINVRIEHIKHSKSRDSFLKRVKENDQKKKEAKEKGTWVQLKRQPAPPREAHFVRTNGKEPELLEPIPYEFMA
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:25957688, PubMed:25901680).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:25957688, PubMed:25901680).
What are the official names of this protein?
60S ribosomal protein L21, Large ribosomal subunit protein eL21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum. Note=Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: LSRB_YERPY
Sequence: MRTQRLKKLALVCALGFACITTAQAAERIAFIPKLVGVGFFTSGGKGAVDAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSVYINQGTPNQLGSMLVDMAANQVKKDQAKVAFFYSSPTVTDQNQWVNEAKKKIQQEHPGWEIVTTQFGYNDATKSLQTAEGILKAYGDLDAIIAPDANALPAAAQAAENLKRANVAIVGFSTPNVMRPYVERGTVKEFGLWDVVNQGKISVYVANEMLKKGDLNVGDKIDIPNIGVVEVSPNRVQGYDYEAKGNGIVLLPQRVIFTKENISKYDF
What is the function of this protein?
Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import.  Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
What are the official names of this protein?
Autoinducer 2-binding protein LsrB, AI-2-binding protein LsrB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 2 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: APY_SOLTU
Sequence: MLNQNSHFIFIILAIFLVLPLSLLSKNVNAQIPLRRHLLSHESEHYAVIFDAGSTGSRVHVFRFDEKLGLLPIGNNIEYFMATEPGLSSYAEDPKAAANSLEPLLDGAEGVVPQELQSETPLELGATAGLRMLKGDAAEKILQAVRNLVKNQSTFHSKDQWVTILDGTQEGSYMWAAINYLLGNLGKDYKSTTATIDLGGGSVQMAYAISNEQFAKAPQNEDGEPYVQQKHLMSKDYNLYVHSYLNYGQLAGRAEIFKASRNESNPCALEGCDGYYSYGGVDYKVKAPKKGSSWKRCRRLTRHALKINAKCNIEECTFNGVWNGGGGDGQKNIHASSFFYDIGAQVGIVDTKFPSALAKPIQYLNAAKVACQTNVADIKSIFPKTQDRNIPYLCMDLIYEYTLLVDGFGLNPHKEITVIHDVQYKNYLVGAAWPLGCAIDLVSSTTNKIRVASS
What is the function of this protein?
Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates.
What are the official names of this protein?
Apyrase, ATP-diphosphatase, ATP-diphosphohydrolase, Adenosine diphosphatase, ADPase.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: PGCA_CHICK
Sequence: MTTLLLVFVCLQAITTAASAELSDSSDGLEVKIPEQSPLRVVLGSSLNIPCYFNIPEEEDTNALLTPRIKWSKLSNGTEIVLLVATGGKIRLNAEYREVISLPNYPAIPTDATLEIKALRSNHTGIYRCEVMYGIEDRQDTIEVLVKGVVFHYRAISTRYTLNFERAKQACIQNSAVIATPEQLQAAYEDGYEQCDAGWLADQTVRYPIHLPRERCYGDKDEFPGVRTYGVRETDETYDVYCYAEQMQGKVFYATSPEKFTFQEAFDKCHSLGARLATTGELYLAWKDGMDMCSAGWLADRSVRYPISRARPNCGGNLVGVRTVYLNPANQTGYPHPSSRYDAICYSGDDFEALVPGLFTDEVGTELGSAFTIQTVTQTEVELPLPRNVTEEEARGSIATLEPMEITATATELYEAFTVLPDLFATSVTVETASPREENVTREEITGIWAVPEEVTTSVSGTAFTTGMAEVSSVEEAIAVTATPGLESASPFTIEDHLVQVTAAPDVALLPRQPISPTGVVFHYRAATSRYAFSFIQAQQACLENNAVIATPEQLQAAYEAGFDQCDAGWLRDQTVRYPIVNPRSNCVGDKESSPGVRSYGMRPASETYDVYCYIDRLKGEVFFATQPEQFTFQEAQLYCESQNATLASAGQLHAAWKQGLDRCYPGWLADGSLRYPIVSPRPACGGDAPGVRTIYQHHNQTGFPDPLSRHHAFCFRALPSVVEEGVTSLFEEEVMVTQLIPGVEGIPSGEETTVETELSSEPENQTAQGTEVFPTDVSLLSARPSAFPPATVIPEETSTNASIPEVSGEFPESGEHPTSGEPSASGAPDTSGEPTSVGFELSGEQSGIGESGLPSVDLQSSGFVPGESGLPSGDVSGLPSGIVDISGLPSAEEEVTVSVSRIPEVSGMPSGAESSGLHSGFSGEISGTELISGLPSGEESGLASGFPTISLVDSTLVEVVTAAPGRQEEGKGSIGVSGEEELSGFPSAEWDSSGARGLPSGAETSGEQSGVPELSGEHSGVPGLSGEAFEVPELSGEHSGVTELSGEHSGLPELSGEPFGVPELSGFPSGLDISGEPSGAPEVSGPVDVSGLTSGVDGSGEVSGVTFISTSLQEVTTPSVAEAEAKEILEISGLPSGETSGMVSGSLDVSGQPSGHIGFGGSASGVLEMSGFPGGAVESSGEASGVEVTSGLASGEESGLTSGFPTVSLVDTTLVEVVTQTSVAQEVGEGPSGMIEISGFLSGDRGVSGEGSGAVQSSGLPSGTGDFSGEPSGIPYFSGDISGATDLSGQPSAVTDISGEDSGLPEVTLVTSDLVEVVTRPTVSQELGGETAVTFPYVFGPSGEGSASGDLSGGASAEGGIETSTAYEISGESSAFPETSIETSTDQEISGEASAYPEISVETSTHLETSGETSAYPEISTETSTIQEVSGETSAFPEISTETSTIQEISGETSAFPEIRIETSTFQEISGETSAFPEIRIETSTSQEARGETSAFPEITIEASTVHETSGETSAFPEISIETSTVHETSGETSAFPEISIETSTVHEISGESSAFPEIRIETSTSQEARGETSAFPEITIEASTIQEISGETSAFPEISIETSTVREISGETSAFPEIRIETSTSQEARGETSALPEITIETSTVHETSGEASAFPEISIETSTRQEARSEASAYPEVSIEASTTQEVSGESSAFPEISVETSTSQEARGETSAFPEIGIETSTAHEGSGETPGLPAVSTDTAATSLASGEPSGAPEKETPDTTSHLITGVSGETSVPDAVISTSAPDVELAQEPRNTEETQLEIEPSTPAASGQETETAAVLDNPHLPATATAALHPASQEAVDALGPTTEDTDECHSSPCLNGATCVDGIDSFKCLCLPSYGGDLCEIDLANCEEGWIKFQGHCYRHFEERETWMDAESRCREHQAHLSSIITPEEQEFVNSHAQDYQWIGLSDRAVENDFRWSDGHSLQFENWRPNQPDNFFFAGEDCVVMIWHEQGEWNDVPCNYHLPFTCKKGTVACGDPPVVENARTFGRKKDRYEINSLVRYQCDHGYIQRHVPTIRCQPNGHWEEPRISCTNPSSYQRRLYKRSPRSRLRPGVVHRPTH
What is the function of this protein?
This proteoglycan is a major component of extracellular matrix of cartilagenous tissues.  A major function of this protein is to resist compression in cartilage.  It binds avidly to hyaluronic acid via an N-terminal globular region.  May play a regulatory role in the matrix assembly of the cartilage.
What are the official names of this protein?
Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP.
What is the protein family that this protein belongs to?
Belongs to the aggrecan/versican proteoglycan family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HIS4_BRUA1
Sequence: MILFPAIDLKDGQCVRLKLGDMDQATIYNEDPAAQAKAFEDQGFEWLHVVDLNGAFAGESVNGTAVEAILKATKNPVQLGGGIRTLAHIENWLSRGLRRVILGTVAVRDPALVMEACKAFPGQVAVGIDAKGGKVAVEGWAEASRLGVIELAKKFEGAGVAAIIYTDIDRDGVLAGINWDSTLALAEAVSIPVIASGGLASMEDIRRLATPEMRKLEGAISGRALYDGRIDPAEALSVLRAAA
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_SALPK
Sequence: MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAADNKGTAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RISB_BACP2
Sequence: MNTIQGHVVAEGLKFAIVVARFNDFITSKLLDGAEDTLLRHGANGDDIDVVWVPGAFEIPYMAKKLAETEKYDAVITLGTVIRGATTHYDYVCNEAAKGIAQSAMSTGVPIIFGVLTTESIEQAIERAGTKAGNKGSESAAAAIEMANLNRTFR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PYRB_CHLL2
Sequence: MKNLTGLCNLPAGDIHTLLDLAAVFKKRLVTPDPSFSVTLQNKRIALVFFENSTRTRFSFDIAARHLGGSTLSFSASGSSVSKGESLGDTIRNLEAMQVDAFVLRHASSGAADFIAGITAKTVINAGDGSHEHPTQALLDIFTLREHFGAVKGLNIVILGDVLHSRVARSNIFGLKTLGANVAVCGPATLLFSDTSHLGVSIFTDLDKAIEWADAALVLRLQLERATGGYLPSLEEYSTHFGLNDERLERVRKHLLVLHPGPINREIEISNNVADRIQPPGYSKSMLLEQVSNGVAVRMAVLQTLLAG
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: COAW_STAAB
Sequence: MKVGIDAGGTLIKIIQEQDNQRTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLEK
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type II pantothenate kinase, PanK-II, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type II pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNF20_HUMAN
Sequence: MMFQDSVAFEDVAVSFTQEEWALLDPSQKNLYRDVMQETFKNLTSVGKTWKVQNIEDEYKNPRRNLSLMREKLCESKESHHCGESFNQIADDMLNRKTLPGITPCESSVCGEVGTGHSSLNTHIRADTGHKSSEYQEYGENPYRNKECKKAFSYLDSFQSHDKACTKEKPYDGKECTETFISHSCIQRHRVMHSGDGPYKCKFCGKAFYFLNLCLIHERIHTGVKPYKCKQCGKAFTRSTTLPVHERTHTGVNADECKECGNAFSFPSEIRRHKRSHTGEKPYECKQCGKVFISFSSIQYHKMTHTGEKPYECKQCGKAFRCGSHLQKHGRTHTGEKPYECRQCGKAFRCTSDLQRHEKTHTEDKPYGCKQCGKGFRCASQLQIHERTHSGEKPHECKECGKVFKYFSSLRIHERTHTGEKPHECKQCGKAFRYFSSLHIHERTHTGDKPYECKVCGKAFTCSSSIRYHERTHTGEKPYECKHCGKAFISNYIRYHERTHTGEKPYQCKQCGKAFIRASSCREHERTHTINR
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 20, Zinc finger protein KOX13.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FADI_ESCF3
Sequence: MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVSELLARSEIPPAAIEQLVFGQVVQMPEAPNIAREIVLGTGMSVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTLGQRLKLFSRLRLHDLLPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSEGKLTNEVMTAYVPPYKAPLSEDNNIRGNSTLADYARLRPAFDRKHGTVTAANSTPLTDGAAAVIMMTESRAKELGLTPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALDRAGLTLADLTLIDMHEAFAAQTLANVQLLGSERFARDVLGRAHATGEVDDSKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_ALKMQ
Sequence: MKKMGLNEIRKLFLDFYEEKEHYVQSSYPLVPHNDKSLLLINAGMAPLKNYFSGVETPPSKRMATCQKCIRTGDIENVGKTSRHATFFEMLGSFAFGDYFKTESIQWGWEFATKYLEMPEDKIWASVYEEDDEAYGIWENQIKMPKERIVRLGKEDNFWEIGVGPCGPCSELYFDRGDKYSCGHDDCKPGCDCDRFVEFWNHVFTQFDKDEAGNYNLLPNPNIDTGMGLERVACIMQDVDSIFEVDTMKHILNSVCTATNTQYNKDVKTNISLRIITDHLRSITFMIGDGILPSNEGRGYVLRRLLRRAARHGKLLGVSKSFLYELMDTVTETYGGAYSELVEKKDYIKKIIQVEEDRFQETIHQGLEILNQHIEEMIGKSENMLNGTYAFKLYDTYGFPLDLTKEILEEREMTVDESEFESEMEKQRNRARKARSGGDTEGWKEDAFDALDKNIQTSFKGYETLRAEGKVLAIIEENQSVNLTSAGKEVVIVLDKTPFYPESGGQIGDIGHIFKDEFEGQVLDTKQGKNQRIHQYIKILRGILQVGDSIQGEVDKEPRHNTERNHTATHLLHKALKGIIGEHVEQAGSLVTPEKLRFDFSHFEGLSSADLSKVELEVNQEILNALNVDTVEASLEEAKKMGAMALFGEKYGDDVRVVKTGDYSVELCGGTHVKNSSEIGTFLILSETGVAAGVRRIEAVTGQEAYHHIKREQGLIQDIESLLKTKGEQLTKRVEELLKETKEKDKELQQLKSKLANQSIDEILNQIEVIEGTNLLVHHFGEQSMEDLRNIGDSLKQKIGSGVIALGAESNDKASFFVTATKDVVEKGVHSGNMIREVAKIAGGGGGGRPDMAQAGGKNPEKIQSALSIVKGLLKNQLNG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_CUPTR
Sequence: MQVYAVGGAIRDELLGKPSQDRDYVVVGATPAEMEAAGYRPVGKDFPVFLHPRTQEEYALARTERKTAMGYKGFAFYCEPDVTLEDDLVRRDLTINAMARAVDADGNLTGPVIDPHGGQRDLAARLFRHVSDAFAEDPVRILRLARFAARFHDFNVAAETMRLMREMVAAGEVDALVPERVWQELARGLMEARPSRMFEVLRECGALARLLPELERLWGVPQRADFHPEVDTGVHVMMVIDCAAALGAPLPVRFAALVHDLGKGTTPEDVLPRHIGHELRSVRLLEEVCARLRVPNECRDLAVVVAREHGHIHRSLELGAAAVVRLLERCDALRKPARFAQALQACEADKRGRKGFEHSDYPQAARLLAAREAAASVDAGAIARACADNVAQIKDRVHAARVEAVAQRLGAQPGE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: LAR_DESUN
Sequence: MTVSGAIPSMTKNRTLVVGGTGFIGQFITKASLGFGYPTFLLVRPGPVSPSKAVIIKTFQDKGAKVIYGVINDKECMEKILKEYEIDVVISLVGGARLLDQLTLLEAIKSVKTIKRFLPSEFGHDVDRTDPVEPGLTMYKEKRLVRRAVEEYGIPFTNICCNSIASWPYYDNCHPSQVPPPMDQFQIYGDGNTKAYFIDGNDIGKFTMKTIDDIRTLNKNVHFRPSSNCYSINELASLWEKKIGRTLPRFTVTADKLLAHAAENIIPESIVSSFTHDIFINGCQVNFSIDEHSDVEIDTLYPDEKFRSLDDCYEDFVPMVHDKIHAGKSGEIKIKDGKPLVQTGTIEEINKDIKTLVETQPNEEIKKDMKALVEAVPISAMG
What is the function of this protein?
Catalyzes the synthesis of catechin from 3,4-cis-leucocyanidin.  Also synthesizes afzelechin and gallocatechin.
What are the official names of this protein?
Leucoanthocyanidin reductase, Leucocyanidin reductase.
What is the protein family that this protein belongs to?
Belongs to the NmrA-type oxidoreductase family. Isoflavone reductase subfamily.
Protein: NADD_CAMJJ
Sequence: MKIALFGGSFDPPHNGHNSVVLEALEKLDIDKLIIMPTYINPFKKSFSADEKQRFLWVKKLWGHLPKVEICDFEIRQKRPVPSIESVKYLYKLYNPSKFYLLIGADHLEKLHLWHDFEKLNSLVEFVIANRNDIGIPKNFKDLKTNKKIASSFIRDTLNTNEVCEEIKDEVKKYYEKLQKN
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RS7_SYNJB
Sequence: MSRRNRAPRRDVPPDPKYGSRLVTMLIRKLMMRGKASLAARILYEALDIVRERTGQDPLPLLENAVRNATPLVEVKARRVGGATYQVPVEVRGERGTSLALRWLVTFSRTRPGRTMAAKLANELIDAANETGSAIRRREEVHRMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RSGA_KLEP3
Sequence: MSKNKLSKGQQRRVNANHQRRLKTTAEKADYDDNLFGETSEGIVISRFGMHADVESADGSVHRCNIRRTIRSLVTGDRVVWRPGKDAADGVNVKGIVEAVHERASVLTRPDFYDGVKPIAANIDQIVVVSAILPELSLNIIDRYLVACEAQDIEPLIVLNKIDLLDDDGLRFVNEQMDIYRNIGYRVLMVSSRTQDGLKPLEAALTDRISIFAGQSGVGKSSLLNALLGLNEDQILTNDVSDVSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEAEQITHGFVEFHDYLGHCKYRDCKHDNDPGCALREAVENGKIAESRFENYHRILESMEQVQVKTRKNFSSSDD
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_METS4
Sequence: MRSYLDFEKPVAELEAKLEELRALGARDGAVAIAEDVARLESKAAAALAELYAALTPWQKTQVARHPQRPHFVDYCDALISEFTPLAGDRSFGEDEAIVGGFGRFRGRPVCVIGQEKGASTEARIRHNFGMARPEGYRKAVRLMDLAGRFGLPVLTFVDTAGAYPGIDAEERGQAEAIARSTEACLALGTPNLALVIGEGGSGGAIALATANRVLMLEHAIYSVISPEGAASILWRDAGRAQDAATAMKITAQDLLRLGVIDAIVPEPTGGAHRDPAAAFRAAEEAIAEGLAGLDGLDAEALRDQRAQKFLEIGRKL
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNN_YERPE
Sequence: MARLIYLMGPSGAGKDCLLSALRNATPQNRVVAHRYITRPADAGAENHVALSKQEFIQRAEQGLFALHWQAHQHCYAIGIEINLWLQHGLDVLVNGSRAYLPEAQRRYRHQLLPLCLTVSPAILAQRLRQRGRENSEQIDARLQRAQHYQQQLPSHCLQLCNDGELQHTLNQLQQLLTLDTPLSDPVEDKPCN
What is the function of this protein?
Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).
What are the official names of this protein?
Ribose 1,5-bisphosphate phosphokinase PhnN, Ribose 1,5-bisphosphokinase.
What is the protein family that this protein belongs to?
Belongs to the ribose 1,5-bisphosphokinase family.
Protein: ZN133_HUMAN
Sequence: MAFRDVAVDFTQDEWRLLSPAQRTLYREVMLENYSNLVSLGISFSKPELITQLEQGKETWREEKKCSPATCPADPEPELYLDPFCPPGFSSQKFPMQHVLCNHPPWIFTCLCAEGNIQPGDPGPGDQEKQQQASEGRPWSDQAEGPEGEGAMPLFGRTKKRTLGAFSRPPQRQPVSSRNGLRGVELEASPAQSGNPEETDKLLKRIEVLGFGTVNCGECGLSFSKMTNLLSHQRIHSGEKPYVCGVCEKGFSLKKSLARHQKAHSGEKPIVCRECGRGFNRKSTLIIHERTHSGEKPYMCSECGRGFSQKSNLIIHQRTHSGEKPYVCRECGKGFSQKSAVVRHQRTHLEEKTIVCSDCGLGFSDRSNLISHQRTHSGEKPYACKECGRCFRQRTTLVNHQRTHSKEKPYVCGVCGHSFSQNSTLISHRRTHTGEKPYVCGVCGRGFSLKSHLNRHQNIHSGEKPIVCKDCGRGFSQQSNLIRHQRTHSGEKPMVCGECGRGFSQKSNLVAHQRTHSGERPYVCRECGRGFSHQAGLIRHKRKHSREKPYMCRQCGLGFGNKSALITHKRAHSEEKPCVCRECGQGFLQKSHLTLHQMTHTGEKPYVCKTCGRGFSLKSHLSRHRKTTSVHHRLPVQPDPEPCAGQPSDSLYSL
What is the function of this protein?
May be involved in transcriptional regulation as a repressor.
What are the official names of this protein?
Zinc finger protein 133, Zinc finger protein 150.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.