PharMolix/UniProtQA huggingface dataset:
Protein: RL2_PELUB
Sequence: MALKTFKPYTKSTRGTILVDRAGLWKGKPFKALVEPKNSMRGRNNNGHITSRNMSGGGHKKMYRLVDFYRKKIDMPGTVERIEYDPNRSCYIMLVKFDDGQHFYYLAPQKIKVGDKVENGSEKEIKVGNCMPLRDIPVGINIHNVELKPGAGGKIARSAGTSVTISGLDGNYSLIKMTSGEVRKIDSRCMATIGVLSNPDQKNIKIGKAGRSRWLGRRPHTRGVVMNPVDHPHGGGEGKTAGGRHPVSPTGQSAKGLKTRDNKSTDKFIVRRRNNRKDSKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SLA_MACLB
Sequence: DQDCLPGWSSHEGHCYKVFNLDKTWEDAEKFCTEQPSNGHLV
What is the function of this protein?
Binds to the platelet GPIb/IX/V receptor system and inhibits ristocetin-induced platelet aggregation in human platelet-rich plasma.  Strongly inhibits platelet aggregation induced by ADP, calcium ionophore, thrombin and collagen.  Does not inhibit U46619-induced platelet aggregation.
What are the official names of this protein?
Snaclec lebecetin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_CERS5
Sequence: MNLFTEIRSLVTAELGAMAEAGELPAGLDLSAVAVEPPRDPAHGDMATNAAMVLAKPAGKPPRAIAEALATRLAADPRILSAEVAGPGFLNLRLRPAVWQGLVARVLQAGDAYGRSTIGAGQRVNVEFVSANPTGPMHVGHVRGAVVGDALARLLVFAGWDVTREYYINDGGAQVDVLARSAYERYREAHGLEPEIREGLYPGDYLIPVGEALKAKYGDSLLDKGEHCWLTDVREFATEMMMQMIREDLAALGVEMDVYSSEKALYGTGKIEAALQRLQDMGLIYEGVLEPPKGKTPEDWEPREQTLFRSTAHGDDVDRPVKKSDGSWTYFAPDIAYHYDKVTRGFDQLIDIFGADHGGYVKRMKAAVAALSDGRVPLDIKLIQLVKLWKNGEPFKMSKRAGTYVTLRDVVEQVGADVTRFVMLTRKNDAALDFDFDKVLEQSKENPVFYVQYANARINSVLRKAREQGMDVADAALACADLDRLDHPAEIALIAKLAEWPRLVEIAARTNEPHRIAFYLHELSSDLHGLWNRGNDEPGLRFLQDDPVVSQAKIALARAVGVVICAGLGILGVTPVEEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_PHOV8
Sequence: MAKKTVAAKKRNVKVDANGQLHVHSSFNNIIVSLANSEGQIISWSSAGKMGFRGSKKNTPYAAQMAAQDCAKVAFDLGLRKVKAYVKGPGNGRESAIRTVHGAGIEVTEIIDVTPLPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RSGA_CLOBM
Sequence: MKGTIIKGIGGFYYIKIDNSEEIIECKARGKFRHTELTPMIGDYVEISVDKNNKGAIEKIYERRSELFRPAVANVTQALVVFSFKNPDINIDLLNKFLLLCEYNNLKAIVCFNKMDLVNKEDYKDIISMIEQAGYDIIFLNAKEERNMDIIKKLIKDNVTVFCGPSGVGKSTMLNKIIGKETMITGNISEKLKRGKHTTRHSELIYVDEGLLVDTPGFSSLDINFMEKEDLLHCIPEFRDFIGECKFTGCLHHREPNCAVKKAVEEGHIHKNRYDFYIKTLEEFMNRRKKKW
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTK_ECOUT
Sequence: MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMQNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRAAR
What is the function of this protein?
Multidrug efflux pump that functions probably as a Na(+)/drug antiporter.
What are the official names of this protein?
Multidrug resistance protein MdtK, Multidrug-efflux transporter.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MdtK subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FMT_HELPJ
Sequence: MRIVFMGTPSFAEVILRALVENEDKKIEVVGLFTQRDKPFGRKKELKAPETKTYILENHLNIPIFQPQSLKEPEVQILKGLKPDFIVVVAYGKILPKEVLTIAPCINLHASLLPKYRGASPIHEMILNDDRIYGISTMLMDLELDSGDILESASFLREDYLDLDALSLKLARMGATLLLSTLKNFHSITRKPQDHMQASFCKKIAKADGLVGFKDAKNLFLKSLAFKSWPEIFLENSLKLLEVELVENEKSHKEGEILAIDERGVLVGCLKGSVRIARLQAVGKKPLKAKDYLNGRRLKVGGILT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: Y224_METKA
Sequence: MPNANQASAGVGALKEVLPGIRALGDLEAAEKVVKRCSGGSTVMVCVIGSTEISRVPGISAAGKTPESTFHTPAGDVELIYYDRIINAEEVPQNPVGAPSPAVITKAVVNLASIPFLTVDAGAAVKPACPYIDLGGEVARDFREGPALSEETYDRLLEFGKTLGKELTRDVDFLTVGESVPGGTTTAMAVMTALGYETSEKFASSSHDSPHDIKERVVKEGLEAQGVEPGDLDAHEAIRRFGDPMMPAVVGIIYGSRTPVLLAGGTQMAPILAYLAEEGQLDPERVFVGTTKYVVEDEDSDIESLFRQVGDYVLFSADPGFSESKFRGFRLYEEGYVKEGVGAGGAQVAAALKTKGEITPKDVLRECERVYERWMDKF
What are the official names of this protein?
UPF0284 protein MK0224.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: SYC_BREBN
Sequence: MGIQLTNTMTRRKEPFHTLEPGKVKMYVCGPTVYNYIHIGNARPAIVFDTLRRYLKYRGYEVTFVQNITDVDDKLIRVANQEGVTVKEVADRYTDAYNADLKSLNVSPPDIQPRVMQTIPEIIEFVQGLIEKGFAYESEGDVYFRTGRFQEYGKLSHQPLDDLQAGARVEINEKKEHPLDFVLWKAAKTGEVTWDSPWGEGRPGWHIECSAMALKFLGEEIDIHAGGTDLVFPHHENEIAQSECFTGKVFARYWLHNGMLNIDNEKMSKSLGNFLLARDLSEKFGGQLIRFFMLQGHYRNPINFSEELIEQAANGLDRITTAYTNLSHRLDTARAEEPNDQAQEQARIIGELRERFIAEMDDDINTANAITVIFDVVKEANLYLRHQNVGETEVRAYMDLLVELTEVLGLDIAEEQELLDSEIDALIEERTEARKARNFARSDEIRDLLAAKGIVLEDTPQGVRWRRK
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HD9_ENCCU
Sequence: MKIKHMPAKKSRLSKAQRDFLDTYFEVNPHPNTQERAYIASQSLVSEEKIRNWFQNRRTRERGDCKIASHRSAFSVNTFEENTSSVHPTSNDLYIRR
What are the official names of this protein?
Homeobox protein HD-9, EcHD-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: PGK_SYNP2
Sequence: MAKKSVANLTEADLSGKRVFVRVDFNVPLNESGVITDDTRIRAALPTIKYLTEKGAKVILGSHMGRPKGQVVDSMRLTPVAARLSELLGQSVTKCDDCVGDAVNQAIANLGNGQVALLENLRFNPGEEKNDPEFAKQLAANADIYVNDAFGTAHRAHGSTEGVTHHVDTSVAGLLIEKELQFLKGAIEAPKRPLVAIVGGSKVSSKIGVIETLLEKCDKLLIGGGMIFTFYKAQGKSVGGSLVEDDKIDLAKSLMEKAQGKILLPTDVIVADKFAPDAEAKTVSVDAIPDGWMGLDIGADSVKVFQEALDGCGTAIWNGPMGVFEFDKFAVGTEAIAKTLAGATETGTVTIIGGGDSVAAVEKVGVADKMSHISTGGGASLELLEGKELPGIVALDDA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINC_ALKCK
Sequence: MTRGKSFVTIKGTKDGLTFLLDDRCSFDELIKELTDKLSANYYKSGEEERPVYVKMDLGNRYLNEEDKAQLEAVVTEGRNMRIEHYDSGVISWEEAQLMKEHAQTTTLTRMIRSGQVVHVKGNVLLVGDINPGGLLTATGSIYVMGALKGRAHAGFEGKRDARICAAMMAPAGLQIADESLYFVDKDEAVEDHMKAAFLDEVNGSIRIERVQRLLDVAAEINKEAVS
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: APOBR_MOUSE
Sequence: MDFLRLRLPGLHQALRGALDSFSAFVSYLVGDTVPTVERQTQAAEELGEVTEGKVVGEEAQEVLEGLRSGQSEGVEAPEETRRCQEGSLAGEQTWGWRADSSARPQAERQDTGSWKAAEDARGQEPSVPLKPEAEPGTHRDRSSNTAQEIWEHGEEEASSGEPLRTCEQKEEEEEVVRAAESGMAEGVESQPTWHSEPGGNAGTEGQHVTEDSKEIDWVAKDMVAEIEWFGAKGIDKEEERMVPMRDGERARAQGTQCPGAESEDQAMLSREAWTVSDREGADSLGVQGTEYGSDPGDNFPGTTGRVWVLEEADKGDQQDEVDEKREAEVRFPIQTLEAERTGEMTEGHIAEEEAMGEQETEGSFEDEERQDLAIRDNGVSLEEEVRAEESSREKRNSWATEPTLVLDTEAKDEPDWEDSPEVSTEELFVGERSEAAQMTPEVLRVKVTEGQDPELVRHSQALTKQLEEGQKGQEETSGAPDLSPERVLSLKEYPGPVGFAGPELEAWGNWSRGVDRRNSQEVKADAEAGKEQTATEQAVEIRAEGGQEAQQPEVFGSGGEEALTSVALNPELEGSQGAEAGTEESVEESKPTENEAAEEEAVVPWEADGTCRKRRLEEVTLSLQDSEDTETSYLAEEIIVGIRAVDTEEGPKWEAGLAPETELGKAWCSEGRGEAGRGTELEETTEKQSGQEVGLVGSAEKVSGYDIQEIDGTEEGEQAEMETSVMAEDIRGTDGVTLGSQAERAEGSITPMETEGLLRDQMLLEEEAGGGQSREQKVHNSEGEIQTLDDSSDQEGQQTHQIPTVAVPGPLESAEATAGAPGDVHSNWNEALLPGSRLDVSVPRSRVLLSRSSSRRRSRPSFHRISVPEPQCDPPSPQPQAERPVPEQSSLQLEETPELSATKPEGTPVPARRKMLGRGFGFAHPGMMQELQARLSQPKPQ
What is the function of this protein?
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL).  Binds and internalizes TRL when out of the context of the macrophage.  May provide essential lipids to reticuloendothelial cells.  Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP).  Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.
What are the official names of this protein?
Apolipoprotein B receptor, Apolipoprotein B-100 receptor, Apolipoprotein B48 receptor, apoB-48R.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein (By similarity).
Protein: DEF2_GLOVI
Sequence: MANQLQVPKQKLAKPPLAIHTLGDRVLRQGSKQISGINDEVRKLAQQMLQTMYSADGIGLAAPQVGVNKRMIVVDIDPENAARPPLVLINPLIKQFSSDLAVDQEGCLSVPSIYADVRRPERVVATYRDLNGRPVTLEATGLLARCIQHEIDHLDGVLFVDRVENQIALAPQLVEKGFAVRDVQVRA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 2, PDF 2, Polypeptide deformylase 2.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: TRM3_EBVA8
Sequence: MLYASQRGRLTENLRNALQQDSTTQGCLGAETPSIMYTGAKSDRWAHPLVGTIHASNLYCPMLRAYCRHYGPRPVFVASDESLPMFGASPALHTPVQVQMCLLPELRDTLQRLLPPPNLEDSEALTEFKTSVSSARAILEDPNFLEMREFVTSLASFLSGQYKHKPARLEAFQKQVVLHSFYFLISIKSLEITDTMFDIFQSAFGLEEMTLEKLHIFKQKASVFLIPRRHGKTWIVVAIISLILSNLSNVQIGYVAHQKHVASAVFTEIIDTLTKSFDSKRVEVNKETSTITFRHSGKISSTVMCATCFNKNSIRGQTFHLLFVDEANFIKKEALPAILGFMLQKDAKIIFISSVNSADQATSFLYKLKDAQERLLNVVSYVCQEHRQDFDMQDSMVSCPCFRLHIPSYITMDSNIRATTNLFLDGAFSTELMGDTSSLSQGSLSRTVRDDAINQLELCRVDTLNPRVAGRLASSLYVYVDPAYTNNTSASGTGIAAVTHDRADPNRVIVLGLEHFFLKDLTGDAALQIATCVVALVSSIVTLHPHLEEVKVAVEGNSSQDSAVAIASIIGESCPLPCAFVHTKDKTSSLQWPMYLLTNEKSKAFERLIYAVNTASLSASQVTVSNTIQLSFDPVLYLISQIRAIKPIPLRDGTYTYTGKQRNLSDDVLVALVMAHFLATTQKHTFKKVH
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM1 and TRM2 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM3 carries an RNase H-like nuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 3, Terminase large subunit.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM3 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Responsible for the nuclear localization of the two others subunits TRM1 and TRM2.
Protein: RUVA_MARSD
Sequence: MIAYIHGKLLEATDKSCIILTPGGVGYELFLTLSAISTLPESGSDVTFYVHSVIREDAFDLYGFPCFDDREVFRTLISVDRLGPKKALAILSQFGPKDLQDLVFREDVKTLSIVPGIGPKSARQILWSLKDKMETLKSATVRSGACPVEGDRSEFLDALSGLRNLGYGDDEVRDFLKDIFDEEPDLDAGGAIRVALKKISQNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RAB6B_CAEEL
Sequence: MSDFGNPLKKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNSNSFHQTSKWIDDVRTERGSDVIIMLVGNKTDLSDKRQVTTDEGERKAKELNVMFIETSAKAGYNVKQLFRRIAGALPGIIKDDPVEPPNVVTMDPIRQRQIVTDEGSCWC
What is the function of this protein?
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:22213799).  Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:22213799).  In its active GTP-bound form, acts redundantly with rab-6. 1 (in its active GTP-bound form) to positively regulate the retrograde trafficking of cargo molecules from endosomes to the Golgi compartment (PubMed:22213799, PubMed:26891225).  Required for the retrograde trafficking of glr-1, a subunit of AMPA-type glutamate receptors (AMPRs), out of early endosomes and into the Golgi compartment in neurons (PubMed:22213799, PubMed:26891225).  Its role in glr-1 trafficking may partly be mediated by its interaction with lin-10 and association with components of the retromer complex such as rme-8 (PubMed:22213799).  Together with rab-6. 2, promotes the retrograde trafficking of mig-14 from endosomes to Golgi structures in the intestine (PubMed:26891225).  Plays a role in the epidermis to promote cuticle integrity and impermeability of the cuticle barrier to exogenous molecules (PubMed:30665892).  May have a role in the glycosylation of the cuticular surface (PubMed:30665892).  Required for seam cell division and alae formation (PubMed:33826611).  Required for grinder formation, which is the feeding organ that breaks down food (PubMed:23792950).  In contrast to rab-6. 1, may play a minor role in the exocytosis of secretory vesicles (cortical granules) during the oocyte-to-embryo transition (PubMed:22992455).
What are the official names of this protein?
Ras-related protein rab-6.2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Perikaryon. Cell projection, dendrite. Golgi apparatus. Cytoplasmic vesicle. Note=Co-localizes with glr-1 at or near punctate structures in the neuron cell body and along the ventral cord dendrites (PubMed:22213799). Co-localizes with lin-10 in neuronal cell bodies (PubMed:22213799). Co-localizes with rme-8 in neuronal cell bodies and dendrites (PubMed:22213799). Co-localizes with rab-6.1 in neuronal cell bodies and dendrites and in Golgi structures in neurons and the intestine (PubMed:26891225). Co-localizes with vps-52 at Golgi structures (PubMed:21613545). Co-localizes with rab-6.1 at vesicular structures throughout the oocyte cytoplasm (PubMed:22992455).
Protein: CASC3_BOVIN
Sequence: MADRRRQRASQDTEDEESGASGSDSGGSPARGGGSCSGSVGGGGSGSLPSQRGGRAGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGDDGEYSEEENSKVELKSEANDAANSSAKDEKGEEKPDTKGTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQAPKSRQELIALYGYDIRSAHNPDDIKPRRIRKPRFGSPPQRDPSWIGERPNKSHRHQGPGGTLPPRTFINRNAAGTGRMSAPRNYSRSGGFKEGRTGFRPAEAGGQHAGRSGETVKHETSYRSRHLEQTPVRDPSPEADAQVLGSPEKEEVAPEIPNPAPDTAPPVPDRPVEKKSYSRARRTRIKAGDAGKVAEEVPPPPEGLTPAPPVPEATPPTPAKTGNWEAPVDSTTGGLEQDVAQLNITEQNWSPGQPAFLQSRELRGMPNHIHMGAGPPPQFNRMEEMGVQGGRAKRYSSQRQRPVPEPPAPPVHISIMEGHYYDPLQFQGPIYTHGDSPAPLPPQGMIVQPEMHLPHPGLHPHQTPAPLPNPGLYPPPVSMSPGQPPPQQLLAPTYFSAPGVMNFGNPSYPYAPGALPPPPPPHLYPNTQAPSQVYGGVTYYNPAQQQVQPKPSPPRRTPQPVTIKPPPPEVVSRGSS
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.  The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.  The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD).  Stimulates the ATPase and RNA-helicase activities of EIF4A3.  Plays a role in the stress response by participating in cytoplasmic stress granules assembly and by favoring cell recovery following stress.  Component of the dendritic ribonucleoprotein particles (RNPs) in hippocampal neurons.  May play a role in mRNA transport.  Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions.  Binds poly(G) and poly(U) RNA homomer.
What are the official names of this protein?
Protein CASC3, Cancer susceptibility candidate gene 3 protein, Metastatic lymph node gene 51 protein homolog, MLN 51 homolog, Protein barentsz, Btz.
What is the protein family that this protein belongs to?
Belongs to the CASC3 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Nucleus speckle. Cytoplasm, Stress granule. Cytoplasm, Cytoplasmic ribonucleoprotein granule. Cell projection, dendrite. Note=Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner. Transported to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA. In nuclear speckles, colocalizes with MAGOH. Under stress conditions, colocalizes with FMR1 and TIA1, but not MAGOH and RBM8A EJC core factors, in cytoplasmic stress granules (By similarity). In the dendrites of hippocampal neurons, localizes to dendritic ribonucleoprotein granules (By similarity).
Protein: VIAA_ECO81
Sequence: MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKAAITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRLNSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRSDYQLIVKYGEFLNEQPELKRLAEQLGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGESWREKMIERPVVHKDYDEQPRGPFIVCVDTSGSMGGFNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGGTDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR
What are the official names of this protein?
Protein ViaA, VWA domain protein interacting with AAA ATPase.
What is the protein family that this protein belongs to?
Belongs to the ViaA family.
Protein: NAMA_BACLD
Sequence: MSNRKLFTPWSLKGVTLKNRIVMSPMCMYSSHEKDGKVQPFHMTHYISRAVGQVGLIMVEATAVTPQGRISDQDLGIWDDAHIDGLAALTSQIKTYGSKTAIQLAHAGRKAEVEGTIYGPSAIPFDENSRTPVEMTKEDIKETVQAFKKGAERAKAAGFDIIEIHGAHGYLINEFLSPLSNKREDEYGGSPENRYRLLREVIDAVKEVWAGPLFVRVSASDYKTKGLDVADYVGFAKWMKEQGVDLIDVSSGAVVPADINVFPGYQVGFADTIRAQAEIQTGAVGLITSGLQAEEILQNGRADLIFVARELLRDPYWPKTAAKQLNTKIEGPVQYDRAW
What is the function of this protein?
Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones.  It also reduces the nitro group of nitroester and nitroaromatic compounds.  It could have a role in detoxification processes.
What are the official names of this protein?
NADPH dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily.
Protein: Y3242_HALS3
Sequence: MSGTPDTLFALAAGATRTAAIEGISAAGADPALMAHTPSADAELLTYGHTVRAPVVPVSPSGCPTPAVITRAVRELVGFESLVIDAGLAEPTGAPTVTTGISPGADIRDETPVPDAEAAYSAAYEFGHGLHTDELVIAETIPGGTTTAMGVLAALGEPRIVSSSLPNNPVALKERVVDDALAASGLEQGDLAGEPVAAVRQMGDPVLAVVAGLAAGALDAGIDVTLAGGTQLATAGALVRHDGVTEPMTLATTSFVAGDDSAGIDALAADQDLAVTVTDPAFEARESHPAMAAYLDGEAKEGVGMGGALALAAEAGIGMDSVRNAIISVYDRV
What are the official names of this protein?
UPF0284 protein OE_3242F.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: USPA_SALTY
Sequence: MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKISLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKYDMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein A.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FERS_STRGR
Sequence: MGVQVDKERCVGAGMCALTAPDVFTQDDDGLSEVLPGREATSGTHPLVGEAVRACPVGAVVLSSD
What is the function of this protein?
Electron transport protein for the cytochrome P-450-SOY system.
What are the official names of this protein?
Ferredoxin soy.
Protein: MURA_TERTT
Sequence: MDKLIIQGGTRISGEIRISGSKNSGLPILAACLLADSPMDICNLPHLNDITTMLALLRCMGVGVTINEKMCVEVDPTTLTDTEAPYELVKTMRASILVLGPTLAKYGKADVSFPGGCAIGSRPVDIHLSGLEAMGAEIAVEGGYIRARAPNGLKGAHFVMDKVTVGGTENLLMAAVLAKGKTVLENAAREPEIVDLADCLVAMGAKIGGIGTDRLEIEGVERLHGCTYTVMPDRIETGTYLVAAAATGGSVKLRDTRADILTAVLQKLEEAGAELEIGESTISLDMHGKRPKAVNLRTAPYPAFPTDMQSQFTAMNAVAEGTGAVTETIFENRLVQVNELNRMGANIKLEGNTALIQGVPRLKGAPVMASDLRASASLVIAGMVADGETVVDRIYHIDRGYECIEEKLQQLGVNIRRVPG
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.