PharMolix/UniProtQA huggingface dataset:
Protein: CYSH_YERPB
Sequence: MSQFNLSELNALPKAKQAAALVLVNGQLEHLTAQERVSWALDNLPGEFVLSSSFGIQAAVCLHLVTRQRPDIPVILTDTGYLFPETYRFIDDLTEKLQLNLQVFRAAHSPAWQEARYGKLWEQGVEGIERYNTLNKVEPMNRALEALGAQTWFAGLRREQSGGRSQLPVLALQRGIFKLLPIIDWDNRQVYQYLTQHGLSYHPLWEQGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
What is the function of this protein?
Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor.
What are the official names of this protein?
Phosphoadenosine 5'-phosphosulfate reductase, PAPS reductase, 3'-phosphoadenylylsulfate reductase, PAPS reductase, thioredoxin dependent, PAPS sulfotransferase, PAdoPS reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POL_RSVP
Sequence: MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSPSDLYSPGSWDPITAALSQRAMILGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTAIGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPPGAEQSRAEPGHAGQAPGPALTDWARVREELASTGPPVVAMPVVIKTEGPAWTPLEPKLITRLADTVRTKGLRSPITMAEVEALMSSPLLPHDVTNLMRVILGPAPYALWMDAWGVQLQTVIAAATRDPRHPANGQGRGERTNLNRLKGLADGMVGNPQGQAALLRPGELVAITASALQAFREVARLAEPAGPWADIMQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRTAPSTLTTPGEIIKYVLDRQKTAPLTDQGIAAAMSSAIQPLIMAVVNRERDGQTGSGGRARGLCYTCGSPGHYQAQCPKKRKSGNSRERCQLCNGMGHNAKQCRKRDGNQGQRPGKGLSSGPWPGPEPPAVSLAMTMEHKDRPLVRVILTNTGSHPVKQRSVYITALLDSGADITIISEEDWPTDWPVMEAANPQIHGIGGGIPMRKSRDMIELGVINRDGSLERPLLLFPAVAMVRGSILGRDCLQGLGLRLTNLIGRATVLTVALHLAIPLKWKPDHTPVWIDQWPLPEGKLVALTQLVEKELQLGHIEPSLSCWNTPVFVIRKASGSYRLLHDLRAVNAKLVPFGAVQQGAPVLSALPRGWPLMVLDLKDCFFSIPLAEQDREAFAFTLPSVNNQAPARRFQWKVLPQGMTCSPTICQLVVGQVLEPLRLKHPSLCMLHYMDDLLLAASSHDGLEAAGEEVISTLERAGFTISPDKVQREPGVQYLGYKLGSTYVAPVGLVAEPRIATLWDVQKLVGSLQWLRPALGIPPRLMGPFYEQLRGSDPNEAREWNLDMKMAWREIVRLSTTAALERWDPALPLEGAVARCEQGAIGVLGQGLSTHPRPCLWLFSTQPTKAFTAWLEVLTLLITKLRASAVRTFGKEVDILLLPACFREDLPLPEGILLALKGFAGKIRSSDTPSIFDIARPLHVSLKVRVTDHPVPGPTVFTDASSSTHKGVVVWREGPRWEIKEIADLGASVQQLEARAVAMALLLWPTTPTNVVTDSAFVAKMLLKMGQEGVPSTAAAFILEDALSQRSAMAAVLHVRSHSEVPGFFTEGNDVADSQATFQAYPLREAKDLHTALHIGPRALSKACNISMQQAREVVQTCPHCNSAPALEAGVNPRGLGPLQIWQTDFTLEPRMAPRSWLAVTVDTASSAIVVTQHGRVTSVAVQHHWATAIAVLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTGIPGNSQGQAMVERANRLLKDRIRVLAEGDGFMKRIPTSKQGELLAKAMYALNHFERGENTKTPIQKHWRPTVLTEGPPVKIRIETGEWEKGWNVLVWGRGYAAVKNRDTDKVIWVPSRKVKPDITQKDEVTKKDEASPLFAGISDWIPWEDEQEGLQGETASNKQERPGEDTLAANES
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.  This recombination event is an essential step in the viral replication cycle.  Has a strong preference for using the 3'-OH at the viral DNA end as a nucleophile.
What are the official names of this protein?
Gag-Pol polyprotein.
What are the subcellular locations of this protein?
[Matrix protein p19]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27, alternate cleaved 1]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27, alternate cleaved 2]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p12]: Virion.
Protein: NIFQ_ENTAG
Sequence: RWAEIVCRSPSCNECCEWHTCFAPED
What is the function of this protein?
Probably involved in molybdenum processing.
What are the official names of this protein?
Protein NifQ.
What is the protein family that this protein belongs to?
Belongs to the NifQ family.
Protein: GCH1L_METTH
Sequence: MITIRIDSLIELMDRVAPPELALPGDRIGYHGPEIEVEAVLVLMDYLEDVAVDGYDLLVLHHPPEVEPPIPYLTVHSNWDVADGGACDALADALGLDVESFLDPDTGVDRICRADLSLEELLERTGVLNPETLRVVNPREYVDRVAVVSGFGLSDKSLIMRAWSEGVSAYLSGDLTHGPAILGRNMDLTLIDAGHHATEMPGLHRLREVIEDFGVMAELLDTGTPWSEYRAAYI
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: YE1F_SCHPO
Sequence: MDTNTLPPKPSISPSIASSFPTVKPFSSQNSTTSNPELSHIEKESNASSIIISQQPLSPSNISSAAPLDETHIATKASASLRNNNVSPHIPSPSSFSSSSSSDLDKSMLDEKHPDSEDITAVSLSTPPFPESIDVARFSSEEKKILSRIRRKLDLRIITCLWITYFLSRSVTYSISLSLTMNKHQGHSLLQTVSGLNYHTLSVGTGLSYVSLIIFDLPSNLLMTRADPRLWLSRIQVTTGIIGACHAVLGTKGSSASGFIALRFFNGLAIAGMWPGFAFYTSRFYRDQHLGKRIGWYYTAAQISSVATSLLSAAFQKMDGLHGLYGYQWMFLIWGVVAFTQGLFLPRWLPCIKHNQHNEKWISWIRIPKFLGFLKASENTGLTPEEEEVHAIYMAEMQVGKSWTLTDLADAFLDVRLWPPIFMFFGVVGISNGLVNYSSLIISEINENFSSVTVSLLVAPIWVFDAIAILTVLPLHDRFHKKMLFFVGSCLFVLAGLLITTFVSNVWGRYVGLLILGFGLGPTVPIIMTWVSSAMGPSHGDVGVAAGLAIVSGLGNLGSVVATSALYSGWKADTTFRRSNETMCGMVGIAIVASIVMHMVQKFNIRRFPFKRIYACLSERRKKELSVT
What are the official names of this protein?
Uncharacterized transporter C1B3.15C.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Allantoate permease family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GMHA_SALTY
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYDYIFSRYVEAVGREGDVLLGISTSGNSGNVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSDNA_BPT5
Sequence: MAKSWGETTGGSNDKIEFLKFNNGITRVRIVSGVLPRYVYWLTNKEGSVAPFECLRFNRDKESFVRGKADPVHELGFFEKELDKDGNRVPLKPKKNYIAFVIDRSDNKLKVMEVKATILKGIQSIMKQLNLATPFDIDISIEKKGKGFDTEYDVQQIAAMQFQIKLQDPNSAESKQYAADVDLIGEAMCDEDGDIIKFEKVPSLEQTYPVPTYEEQKEAIQAFMEGRENKDDDAKSGNSNAGSQKGIDQEAASDLDD
What is the function of this protein?
Required during DNA replication.  Displaced viral DNA strands are transiently coated with the ssDNA-binding protein.  It is then probably removed by the replisome that performs lagging strand synthesis or during the events that lead up to the recombination process.
What are the official names of this protein?
Probable ssDNA-binding protein, Protein D11.
Protein: GACZ_DICDI
Sequence: MTTTNTSIFGPRVNNSKFNNNNNNNNNNNNNNNNTSNNNNSNIIKPPQVVQETQQQQQAQQQPLQTNEEVCVICKSKNVQVCTGCLMVYYCGAEHQNIDWPNHKSLCSGLNRRNDLLDRAEKSKDLRKKLQSDIFSSGNRVSNSNNNSSIYSNSTGNINNNNNSNNNNIKGGIGGGAVTNSSTVMAPERKSIAISNIKHLQQQIQQTQQTQQQPPPTTTSIPTQPNSSSFNKPTAKKPGTSFKSSSSGDNTPINQSPSSSSSSLVSSTNNNNNNNNNNNNNNNINSNSNNMSGSSGGIKALQNQLQNSINNKPSNTTSNSPNPSPPSSTFVPNSNNNSNSNSSSGSGKSNLNISLKSSTSSSPVTSTYLYNNNNSNSNSNSNNSSTETTTCISSNSNNSSNIENSDNTNEENGMKNIKNKLSQINFGAPPPSFKKPTSKVIENEDNNNSNNDGTLKQSSSSDSIYFNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNFDINNSNNIINNKQSTCSSIDGLSYNNNNSGSSLKNSVPPTTSNTPPRKRSSGGSSSSNNSNIGSNGNRIGFIKEHKKNQSLPDSFVDFYQSNKNQSNGYESLLDNDDNKTRGYGSFNENDDSHEECDDDDDDDDGGGQDGDDGLDGTEFKRGRNRPTGLRTNNNAVFEWESGTIEYSTNNTSQHKKLGVGSRGGNSFSKDTQSQSTNSTTTDDHQTGSILNSNSGSSDDLQQQQTQTQQQQSQLSAGVGRIAGKFRMIGGDIKKKAAIVGTLTKNKVSEVTSKSKSSTSVNNNNNDEVDHNENNNNNNNNINNNNNNNNNNIENIIFGIPLEEAVKKSATLHPLIPDVIYKSIEYIREKGIQEEGIFRLSGSANAITLLKNEFDRGVNVDLYQQLDQHVVSGILKLYLRQIPETLFTQDFGEELEELRVGGNSSDAISKRIAGSIILLQRLPESNRCILHYLCNLLNAISFEPSTKMGTVNLAIVFAPTLGVSVEVMTCLISYYDEIFGIQTYNYNS
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacZ, GTPase activating factor for raC protein Z.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_DEIRA
Sequence: MTAPEQTFRNKKQRKQQVKLRKPGFAVAKYVRMSPRKVRLVVDVIRGKSVQDAEDLLRFIPRSASEPVAKVLNSAKANALHNDEMLEDRLFVKEAYVDAGPTLKRLIPRARGSANIIKKRTSHITIIVAEKGNK
What is the function of this protein?
The globular domain of the protein is located by the polypeptide exit tunnel on the outside of the subunit while an extended beta-hairpin forms part of the wall of the tunnel.  Forms a pair of 'tweezers' with L32 that hold together two different domains of the 23S rRNA.  Interacts with the tunnel-blocking modified macrolide azithromycin.  Upon binding of the macrolide troleadomycin to the ribosome, the tip of the beta-hairpin is displaced, which severely restricts the tunnel.  This and experiments in E. coli have led to the suggestion that it is part of the gating mechanism involved in translation arrest in the absence of the protein export system.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL10_AZOC5
Sequence: MDRAEKQELVTTLSEVFKSTSVVVVAHYSGLTVAQMSKLRRQMKAEGATVKVAKNRLAKIALEGSDVAHVATLLKGPTIIAYSSDPVAAPKVAVEFAKANDKFVILGGAMGKTALNADGVKALATMPSLDELRAKLVGLIQAPATKIAQLSTAPAAKLARVFGAYAKQNEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: METK_ECO27
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_PETMA
Sequence: MPTTLIFTSFFLALLGLSLQRKHLLSLLLTLESMALALYVSTALWALNNTSLPIMAAPLIILTFSACEAGMGLSLMIATARTHNTDQLKALNLLKC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: QUEG_SYNY3
Sequence: MGIAPVSETENDEAAQRLQSWIALGYNADMAWMANPKRQNIRELLPSARSVIAVGLNYYTPHQRSGDPAHGKISRYAWGRDYHRVLTKKLKALNLWLEQQVPDLQSRYYVDTGPIQEKAWAERAGLGWVGKNGNLISRDYGSWLFLGEIVTNITLQGDRPHSQHCGTCTRCLEACPTQAIVEPFVVDSNKCIAYHTIENRAEILPTAIADNLQGWVAGCDICQDVCPWNQRFAQPTDVADFDPYEGNLNPELETLANITEADWQQQFTASALRRIKPAMLRRNAQANLQ
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase, Queuosine biosynthesis protein QueG.
What is the protein family that this protein belongs to?
Belongs to the QueG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CATB3_ARATH
Sequence: MAVYNTKLCLASVFLLLGLLLAFDLKGIEAESLTKQKLDSKILQDEIVKKVNENPNAGWKAAINDRFSNATVAEFKRLLGVKPTPKKHFLGVPIVSHDPSLKLPKAFDARTAWPQCTSIGNILDQGHCGSCWAFGAVESLSDRFCIQFGMNISLSVNDLLACCGFRCGDGCDGGYPIAAWQYFSYSGVVTEECDPYFDNTGCSHPGCEPAYPTPKCSRKCVSDNKLWSESKHYSVSTYTVKSNPQDIMAEVYKNGPVEVSFTVYEDFAHYKSGVYKHITGSNIGGHAVKLIGWGTSSEGEDYWLMANQWNRGWGDDGYFMIRRGTNECGIEDEPVAGLPSSKNVFRVDTGSNDLPVASV
What is the function of this protein?
Thiol protease that possesses high activity toward the cathepsin synthetic substrate Arg-Arg-7-amino-4-methylcoumarin (RR-AMC) and the papain substrate Gly-Arg-Arg-AMC (GRR-AMC).  Can cleave the papain substrate Phe-Arg-AMC (FR-AMC) and the caspase-3 substrate Asp-Glu-Val-Asp-rhodamine 110 (DEVD-R110).  Has no activity towards the caspase-6 substrate VEID-AMC, caspase-8 substrate IETD-AMC and caspase-1 substrate YVAD-AMC (PubMed:27058316).  Plays a central role in plant programmed cell death (PCD).  In addition to its role in protein degradation, may cleave and/or degrade a number of target proteins, activating signaling towards PCD.  Contributes to the increase of caspase-3-like activity after UV-C-induced PCD and is required for abiotic stress-induced PCD (PubMed:27058316).  Functions redundantly with CATHB1 and CATHB2 in basal defense and distinct forms of plant programmed cell death (PCD).  Participates in the establishment of basal resistance against the bacterial pathogen Pseudomonase syringae pv.  tomato DC3000.  Required for full levels of PCD during resistance (R) gene-mediated hypersensitive response (HR).  Involved in the regulation of senescence, a developmental form of PCD in plants (PubMed:19453434).  May be involved in the degradation of seed storage proteins during seed germination (PubMed:24600022).
What are the official names of this protein?
Cathepsin B-like protease 3, Cathepsin B3, AtCathB3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: LES1_SCHPO
Sequence: MQPRFLLHGALLALGIQLCLSIGKITGHISSIEATAADIHDAPSTTTKYVQRTVYAGREKGKIGGPADSWPQRKLDDFLQNHGVKSLDVPPIETPSQFWRKPLQYVSKVTDKCKSFYEKEKNHASHNAQKLDVWIFNSWTNSELSRWLIKNKYEVPEPGTREQLLETVFQASMGDAISTNDELESWSNNLLLSMLDQKNITVPIGASHDDLIVLARRYYDIEERKSQDKVTNITDSQPAPYMKEIIHLWSDGRLIDFLRERNIPISVLSPRETLLKEAYANRFTPRVMIASNVLDGWSSEDLLDWIWKYNKRGSIFSHVAYNSRHELIHAAKLFYMDVASEWSSSDMASLNDSLYSHPSVSKQSTWTEEELKEELESFGELVPVPFSSTKAFERLLPHLYYYLRGPAFLNRIHYWQTFLGNSLKRAFVLSQ
What is the function of this protein?
Inner nuclear envelope protein involved in nuclear fission, which is achieved via local disassembly of nuclear pores within the narrow bridge that links segregating daughter nuclei (PubMed:32848252).  Les1 restricts the process of local nuclear envelope breakdown to the bridge midzone to prevent the leakage of material from daughter nuclei during mitosis (PubMed:32848252).
What are the official names of this protein?
Nuclear bridge Ish domain protein les1, Lem-like enriched in stalks protein 1.
What are the subcellular locations of this protein?
Nucleus inner membrane. Note=Concentrates at the stalk of each daughter nucleus during anaphase.
Protein: RL34_ALKCK
Sequence: MGKPTFQPNNRKRKKNHGFRARMATKNGRKVLARRRQKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL21_HAEIE
Sequence: MYAVFQSGGKQHRVSEGQVVRLEKLELATGATVEFDSVLMVVNGEDVKIGAPVVAGAKVVAEVVAQGRGEKVKIVKFRRRKHSRKQQGHRQWFTEVKITGIQA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: NU1M_SARHA
Sequence: MFTINLLLYIIPILLAVAFLTLIERKVLGYMQFRKGPNMVGPYGLLQPFADAVKLFTKEPLHPLTSSTSMFIIAPILALSIALTIWTPLPMPNTLLDLNLGLIFILSLSGLSVYSILWSGWASNSKYALIGALRAVAQTISYEVSLAIILLSIMLINGSFTLKTMSVTQENFWLIITTWPLAMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFAMFFLAEYANIIAMNAITTILFLGPSLMPNLSHLNTMSFMTKTLLLTMTFLWVRASYPRFRYDQLMHLLWKNFLPMTLAMCLWFISLPIALSCIPPQM
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YOAH_SALCH
Sequence: MFAGLPSLSHEQQQKAVERIQELMSQGMSSGEAIAQVAGELRANHTGERIVARFEDEDE
What are the official names of this protein?
UPF0181 protein YoaH.
What is the protein family that this protein belongs to?
Belongs to the UPF0181 family.
Protein: HIS82_THIDA
Sequence: MSRTSTSRYWSAVVGALTPYVPGEQPKLANLVKLNTNENPYGPSPRVLEALRGEVGDTLRLYPDPNSDRLRAAIAAYHAVSPDQVFVGNGSDEVLAHTFLALLKHERPVFFPDITYSFYPVYCGLYGIAHRAIPLDDAFEIRVDDYLAPKGGVIFPNPNAPTGRLLALGEIERLLAANRDSVVVIDEAYVDFGGDSAVPLVARHPQLLVTRTLSKSHALAGLRVGYAVGQAPLIEALNRVKDSFNSYPLDRFAQAGALASIEDRAYFESICARVIATRTRLVDAMESLGFEVLPSAANFIFARHPAHDGEALAARLRERSIIVRHFKNPARIAPFLRITVGTDAQCDALVDALKALC
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: APT_SYNR3
Sequence: MAESLEQQLRALVRDVPDFPKPGILFRDLTPVMRDPQAWKQVMEGMQQSLAGLQPEVIVGIEARGFIVGTSLAMTMGLGFVPVRKPGKLPGPITAVDYALEYGSDRLEIQEGALSGCQRVLVVDDLLATGGTAAACAELVSRAGGAVCGYGFVAELTALGGRSKLPGGVLVESLIHY
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNNC2_PRODO
Sequence: GKSEEELAEFFRIFDKNADGYIDAEELAEIIRSSGEHVTDEEIEELMKDGDK
What is the function of this protein?
Troponin is the central regulatory protein of striated muscle contraction.  Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C.  The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments.
What are the official names of this protein?
Troponin C, skeletal muscle.
What is the protein family that this protein belongs to?
Belongs to the troponin C family.
Protein: PEDF_HUMAN
Sequence: MQALVLLLCIGALLGHSSCQNPASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSTSPTTNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDLISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGNPRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGKPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLFIGKILDPRGP
What is the function of this protein?
Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells.  Potent inhibitor of angiogenesis.  As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
What are the official names of this protein?
Pigment epithelium-derived factor, PEDF, Cell proliferation-inducing gene 35 protein, EPC-1, Serpin F1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted. Melanosome. Note=Enriched in stage I melanosomes.
Protein: PCKA_DICDI
Sequence: MNQAVAESINKSLKSSTADYTPKGYHITELESDSIYLDEHFSGNAKIFHNPAVAVLYEQALAFEHGSAITSTGALVTRSGVKTGRSPKDKRIVKEPSSQDDIWWGPVNIAMDDLSFMINRERAIDYLNTQEKIYVIDGYAGWDPKYRIKVRVICARAYHALFMHNMLIRPANREELRNFGEPDYTIYNAGQFPANRYTKGMSSSSSIAIDFARKEMVILGTQYAGEMKKGILTIMMYLMPKMGVLPLHSSCNQARNNGDTTLFFGLSGTGKTTLSADINRELIGDDEHVWTDTGCFNIEGGCYAKCIDLSREKEPEIFDAIKFGAVLENVVYNEYSRKVDYNDVSITENTRCAYPLEHIPNAKFPAIAGHPKNIIMLTCDAFGILPPVSRLDANQVMYHFIQGYTAKVAGTEVGVTEPTATFSSCYGEPFIVWHPTKYAEMLASQLHKHSARAWLINTGWTGGSHGVGSRIKLAYTRAIIDAIHSGELEKIPTTKMDVFGFQVPNSCPGVPSEILMPINGWADKEKYVSTMHKLAKLFIENFKKFQDKASPELVAAGPILPQ
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP).
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
Protein: ATPF_LACPL
Sequence: MLSHLIIGASGLYLGDMLFIGISFIVLMALISVVAWKPITKMMADRADKIANDIDSAQKSRQEASDLADQRRDALSHSRAEASEIVADAKKSGEKQRSSIVADAQNEATQYKQNARKDIEQERQDALKNVQSDVADISVAIATKIIKKQLDPEGQQALINSYIEGLGKHES
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ENO_BACMK
Sequence: MSTIIDVYAREVLDSRGNPTVEVEVYTESGAFGRAIVPSGASTGEHEAVELRDGDKSRYLGKGVLNAVNNVNEAIAPEIVGFDVTDQAGIDRAMIELDGTPNKGKLGANAILGVSMAVAHAAADFVGLPLYRYLGGFNAKQLPTPMMNIINGGSHADNNVDFQEFMILPVGAPTFKESIRMGAEVFHALKAVLHDKGLNTAVGDEGGFAPNLGSNREALEVIIEAIEKAGYKAGENVFLGMDVASSEFYNKETGKYDLAGEGRTGLTSAEMVDFYEELCKDFPIISIEDGLDENDWDGHKLLTERIGDKVQLVGDDLFVTNTQKLAEGIEKGISNSILIKVNQIGTLTETFEAIEMAKRAGYTAVVSHRSGETEDATIADIAVATNAGQIKTGSMSRTDRIAKYNQLLRIEDELGEIAVYDGIKSFYNIKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SP2P_BACSU
Sequence: MRNKRRNRQIVVAVNGGKAVKAIFLFIVSLIVIFVLSGVLTSLRPELRPSSDSFYGIAEELPGDVFAHLLQMENHYFASDLSQTDSSFHLSRLSLKLATSINLEDPRSFLGRELPGFAQFDTEILLAGQGTDYTNMPAESPPPSKVMEEEREANLAEIEKQQTQSDNAQKDPPKQTTGDKKVVFIYHTHNTESYLPLLKGETDPDMARHSKANVTLVGDMFGQALESQGIGATVNKTDIQSKLNKKGLNYARSYDESRPVVKDALASNKNLQYIIDIHRDSRRKKDTTATIKGKSYARVAFVVGKKSKNFEENYKIASELHKLMEKKYPGLSTGVFSKGSPGDNGVYNQDLTDRALLLEFGGVDNNLEELQRAANAAADVFSEMYWDAEKVNAASGETKKQ
What are the official names of this protein?
Stage II sporulation protein P.
Protein: RS5_BACSU
Sequence: MRRIDPSKLELEERLVTVNRVAKVVKGGRRFRFAALVVVGDKNGHVGFGTGKAQEVPEAIRKAVEDAKKNLIEVPMVGTTIPHEIIGRFGAGNILLKPASEGTGVIAGGPVRAVLELAGVADILSKSLGSNTPINMIRATLQGLSELKRAEDVAKLRGKSVEELLG
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy; many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).
What are the official names of this protein?
30S ribosomal protein S5, BS5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.