PharMolix/UniProtQA huggingface dataset:
Protein: RS18_RICRS
Sequence: MLKSNNASETAAHKVGDKTAKKVFFRRRKGCPLSVPNAPVIDYKNPELLIKFVSEGGRMLPSRITNVCAKKQRKLNNAIKIARILALLPFVFQAK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: SSPC_BACSU
Sequence: MAQQSRSRSNNNNDLLIPQAASAIEQMKLEIASEFGVQLGAETTSRANGSVGGEITKRLVRLAQQNMGGQFH
What is the function of this protein?
SASP are bound to spore DNA.  They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation.  They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light.
What are the official names of this protein?
Small, acid-soluble spore protein C, SASP.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta-type SASP family.
Protein: APOE_HYSBR
Sequence: MKVLWAVLVVTLLAGCQADVEPALEVGEPAPEVREPAMWQSGQPWELALGRFWDYLRWVQTLSDQVQEELLSSQVTQELTVLMEDTMKEVKAYKSELEQELGPMAEDTKARLSKELQAAQARLGADMEEVRNRLTQYRSEVQTMLGQSAEELRARLASHLRKLRKRLLRDAEDLQKRLAVYKAGAQEGAERGVSAIRERLGSLVEQGRLRAAQTSQPLRERAQAWGERLRGRLEEVGGQARDRLDVVREQMEEVRAKVEEQAEAFQARLKGWFEPVVEDMRRQWAELIEKVQVAVGASTPAPSEKH
What is the function of this protein?
APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids.  APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance.  Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma.  As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL).  It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles.  Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells.  A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes.  APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues.  By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis.  APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis.  First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues.  Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes.  APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting.
What are the official names of this protein?
Apolipoprotein E, Apo-E.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix. Note=In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins. Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans- dependent manner. Lipidation induces the release from the extracellular matrix.
Protein: CS012_BOVIN
Sequence: MPVAVEDIMRLLCSISEERKMKAAVKHSGRGALVTGAVAFVGGLVGGPPGLAVGGAVGGLLGAWMTSGQFKPVPQIIMELPPAEQQKLFNEATAIIRHLEWTDAVQLTMLVMGSEALQKQLLAMLANYVTKELRAEVQYDD
What are the official names of this protein?
Protein C19orf12 homolog.
What is the protein family that this protein belongs to?
Belongs to the C19orf12 family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion membrane; Single-pass membrane protein. Endoplasmic reticulum. Cytoplasm, cytosol. Note=In response to oxidative stress, relocates to the cytosol forming aggregates that partially co-localize with mitochondria.
Protein: RL25_SALTI
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGSEAPIAIELDHDQVMNMQAKAEFYSEVLTLVVDGKEVKVKAQAVQRHAYKPKLTHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: NU4M_AZEFE
Sequence: PIAGSMVLAAILLKLGGYGIIRIMQTLPTTKTDLFIPFITLALWGATLANLTCLQQTDLKSLIAYSSISHMGLVVAAITIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRVLILTRGLHNILPMATTWWLLTNLMNIATPPTLNFTSELLIMSSLFNWCPTTIILLGLSMLITASYSLHMFLSTQAGPTLLNNQTEPTHSREHLLMALHLIPLMLISMKPELII
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ATP6_KORVE
Sequence: MPHQLWFTAFLNQYLAGPVSAMMSVLHVPNPHPRAPISNYVAMEILVFLLLVLFFIATRISLSWDKPGVLQHIAEGMNNFVSNQGEEMIGHGYETYTSYIVTLGVFILSMNLIGLIPGFEAPTAFPSVPLGCALVTWFFYHVHGLRENGVIGYLKHFLGPVWWISPLLFVIEICSHFARIMSLTIRLYANMFAGDMVTLAFFSLVPLGFPVVFMGLHIFVSLIQTYIFITLAAVYLAEATAHGHD
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL15_METKA
Sequence: MVVRRKKKSPKKYRGSRTHGGGSHKNRRGAGNRGGRGMAGSHKHKWFHVIKYMPDHFGKRGFNRPPKVVREPNTINVGELDALADKLLEDGIAEKDGDKIVIDVTDERLKPYGGPFDKVLGGGHVKRPLVVVAPEFTERAVEKLEEAGGEAREA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: FETP_BURCH
Sequence: MARMIQCAKLGKEAEGLDFPPLPGELGKRIYESVSKEAWQGWLKQQTMLINENRLNMADPRARQYLMKQTEKYFFGDGADQASGYVPPTEG
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: DAPF_HELPY
Sequence: MVFYKYSGSGNDFLIVQSFKKKDFSNLAKQVCHRHEGFGADGLVVVLPSKDYDYEWDFYNSDGSKAGMCGNASRCVGLFAYQHAIASKNHVFLAGKREISICIEEPNIIESNLGNYKILDVIPALRCEKFFSSGSVLEHIPTFYLIDTGVPHLVGFVENKEGLNSLNTLELRALRHEFNANINIAFIENKETIFLQTYERGVEDFTLACGTGMAAVFIAARIFYNTPKKAALIPKSNESLELSLKNDGIFYKGAVRYIGMSVLGMRVFENGCF
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITBP2_MOUSE
Sequence: MSLLCYNKGCGQHFDPNTNLPDSCRYHPGVPIFHDALKGWSCCRKRTVDFSEFLNIKGCTVGLHCAEKLPEVPPQPEGPATSSLQEQKPLNTIPKSAETLFRERPKSEMPPKLLPLLISQALGVALEQKELDQEPGAGLDNSLIWTGSSCQNPGCDAVYQGPESDATPCTYHPGAPRFHEGMKSWSCCGIQTLDFGAFLAQPGCRVGRHDWAKQLPASCRHDWHQTDSVVVLTVYGQIPLPAFNWVKASQTELHVHIVFDGNRVFQAQMKLWGVINVEQSSVSLMPSRVEISLVKADPGSWAQLEHPDSLAEKARAGVLLEMDEEESEDSDDDLSWTEEEDEEEEEAMGE
What is the function of this protein?
May play a role during maturation and/or organization of muscles cells.
What are the official names of this protein?
Integrin beta-1-binding protein 2, Melusin.
Protein: DCUP_HELHP
Sequence: MIFIDACFRKPTPYTPIWLMRQAGRYLSEYKQTRTKAGSFLSLCKNVELATEVTLQPVEILDVDAAILFSDILVVPLEMGLPLEFLAGEGPKFNRTISNVSDVVNLQEGAHKRLTYVYDTLSSIRSKLPKEKALIGFCGSPWTLATYMIEGQGSKTYAKSKAMLYKEPYILKTLLETLSEELKLYLEGQIRAGANAVQIFDSWASALECEVYFEFSWKYMKDIAQYIKGKYPHIPVMLFPKGIAGYLDKIDGCFDVFGVDWGTPMALAKSYLGTKYVLQGNLEPSRLYDKESMERGIDEILKIMGKEKGHIFNLGHGMLPDLPRENAIALVQMVREKSKR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOR3_TTV1K
Sequence: MHIIGPVSFSRTVFLDFYNYLLQSGLYETLRIDRKYIEYTLKNKYATLRLYGKYVHT
What are the official names of this protein?
Uncharacterized 6.9 kDa protein.
Protein: GLO2_PECAS
Sequence: MNLISIPALQDNYIWLLSNKANRCVIVDPGEASPVLNALDQNALLPEAILLTHHHNDHVGGVSEILNHYPNLPVFGPKETAKCGATYLVEEGNTVSLLNSEFSVIEVPGHTSGHIAYYNAPFLFCGDTLFSAGCGRIFEGTPKQMYESIQKIAELPDDTVVCCAHEYTLSNLRFSNDIWPEDPDIESYLHKISQIREKSQSSLPTTLGLERRINLFLRCHEIDLKRKISNEPENIENWQVFKMLRSKKDCF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: STADS_BRANA
Sequence: MALKFNPLVSQPYKLASSARPPVSTFRSPKFLCLASSSSPALSSKEVESLKKPFTPPREVHLQVLHSMPPQKIEIFKSMEDRAEQNLLPHLKDVEKSWQPQDFLPDPASDGFEDQVKELRERARELPDDYFVVLVGDMITEEALPTYQTMLNTLDGVRDETGASPTSWAVWTRAWTAEENRHGDLLNKYLYLSGRVDMRQIEKTIQYLIGSGMDPRTENNPYLGFIYTSFQERATFVSHGNTARQAKEHGDLKLAQICGTIAADEKRHETAYTKIVEKLLEIDPDGTVVAFADMMRKKISMPAHLMYDGRDDNLFDNFSSVAQRLGVYTAKDYADILEFLAGRWRIESLTGLSGEGNKAQEYLCGLTPRIRRLDERAQARAKKGPKIPFSWIHDREVQL
What is the function of this protein?
Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons Delta(9) and Delta(10) of the acyl chain.
What are the official names of this protein?
Stearoyl-[acyl-carrier-protein] 9-desaturase, seed specific, chloroplastic, Stearoyl-ACP desaturase, Acyl-[acyl-carrier-protein] desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MED19_DROME
Sequence: MMSNYGNMMDSPKSSPHGGGRSPVVARQDSSGTLKTTISLGKTPTIIHTGPFYSMKEPPAKAELTGDKDLMTEYGLHHTLTKFKEKKFKESLASFLQNIPGINDLITHPVENSTLRSVIEKPPIGGKELLPLTPVQLAGFRLHPGPLPEQYRTTYVTPARKHKNKHKKQKHKDGVTTGQESTLLDSAGLETYEKKHKKQKRHEDDKERKKRKKEKKRKKKNQSPEPGVGLLPGGASLGGAAGVMGATSLGSLGGGPGGPGLSSLSASMGPGVVGNMNSFSSSMQMQQQQQMPMQQQQMSSGGLLGSVLGTSGGPGGGGGGGGGGGGGVGGSLLMSQF
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 19, Mediator complex subunit 19.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 19 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS12_STRPG
Sequence: MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVQTKMAAPQKRGVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RISB_YERPN
Sequence: MNVIEGVVATPNARVAIAIARFNNFINDSLLDGAIDALKRIGQVSDDNITVVWVPGAYELPLVANVLAKTNRYDAVIALGTVIRGGTAHFEYVAGEASSGLSSVAMNSDIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVIKAIKG
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: Y2198_SULIA
Sequence: MKITPIAFESLGVRSQATLIETKDLRVLVDPAISLAPRRYNLPPHQREVDRLTELAKVLVDVAKDVDVIIVSHYHYDHHDPGYVIPTDIYKNKLVFIKDPQNMINNSQKYRRAPRFLRSIKDKPSKIEIADGKTFEVGHTTISFSPAVPHGADERLGYVIQVAISDKDSTVIFTSDIEGAPKDVHLKFTKEKMPKTIIIDGPLSYLLGRVLKEEELEKSIRNMEEIVKNGLETVIIDHHVLRDINYAEVLKPVYDIAKDLGVRVTTAAEYLNLEPLILEARRKELFKEDNRPARLPRGLANLLSAGEG
What are the official names of this protein?
UPF0282 protein M1627_2198.
What is the protein family that this protein belongs to?
Belongs to the UPF0282 family.
Protein: IMPB_SALTM
Sequence: MFALADINSFYASCEKVFRPDLRNEPVIVLSNNDGCVIARSPEAKALGIRMGQPWFQVRQMRLEKKIHVFSSNYALYHSMSQRVMAVLESLSPAVEPYSIDEMFIDLRGINHCISPEFFGHQLREQVKSWTGLTMGVGIAPTKTLAKSAQWATKQWPQFSGVVALTAENRNRILKLLGLQPVGEVWGVGHRLTEKLNALGINTALQLAQANTAFIRKNFSVILERTVRELNGESCISLEEAPPAKQQIVCSRSFGERITDKDAMHQAVVQYAERAAEKLRGERQYCRQVTTFVRTSPFAVKEPCYSNAAVEKLPLPTQDSRDIIAAACRALNHVWREGYRYMKAGVMLADFTPSGIAQPGLFDEIQPRKNSEKLMKTLDELNQSGKGKVWFAGRGTAPEWQMKREMLSQCYTTKWRDIPLARLG
What is the function of this protein?
Involved in UV protection and mutation.
What are the official names of this protein?
Protein ImpB.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
Protein: TPS5_VITAC
Sequence: MSLAYSQATSLLLSSTTRGGVPSLMHIPATNSPARINTGATPFWKLPFPARPLRQYKSITRARNQVILTAEKSVDVDTEKNTHHQKATAETTRELVERIRWMLQNMDDGELSVSPYDTAWVALVEDIGGSGRPQFPTSLEWISNNQYPDGSWGDRKFLFYDRILNTLACVVALKTWNMHPDKCEKGLKFIKENIHSLENENEEYMPVGFEVAFPSLIETAKKLGIEIPDDSPGMKDIYAKRHLKLKKIPMDLLHKMPTSLLFSLEGMKGLDWQKLLNLRFEGSFLSSPSSTAYALQHTKDELSLQYLLKAIKKFNGGVPNAYPVDMFEHLWSVDRLQRLGISRYFEPEIEECMKYAYRYWTDKGICWARNTNVQDVDDSSMGFRLLRLHSFPVTIDAFKQFEKGGEFCSIPGQSTHAITGMYNIFRASQVLFPGDHILADARKYSAKFLHQKRVNEAIVDKWIITKDLPGEVGYALDVPFYASLPRLEARFFLEHYGGDDDVWIGKTLYRMLYVNCDTYLELAKLDYNVCQAVHQHEWTNIRRWYKDCSVGEFRLAERSLLRAYYIAASTVFEPERSGERLAWAKTAILLETILSQKLHSEEKHTVVDEFKHGSISISGNGRRHQTRISLAETLIYTVNQLSSDIKQAHGRDIHQQLHHAWQKWLTTWEGRGNLGEAEAELLVRTLHLSSGLDESWFSHPKYQQLLEVTSKVCHQLRLFQNRKMHDPKGCTIDLVTGTTFQIEAGMQELVKLVFTKSSEDLDAHTKQSFFAIARSFYYTAYCDPEAIESHVDKVLFDKVV
What is the function of this protein?
Involved in the biosynthesis of labdane-type diterpenoid including cleroda-dienols, and peregrinol lactones and furan derivatives, dopaminergic diterpenoids that can bind to dopamine receptors in the human pituitary gland, have probably ability to lower prolactin levels, and are used to treat menstrual cycle disorders (e. g.  premenstrual syndrome and mastodynia) (Probable).  Terpene synthase that produces kolavenyl diphosphate from geranylgeranyl diphosphate (GGPP) (PubMed:29315936).
What are the official names of this protein?
Kolavenyl diphosphate synthase TPS5, chloroplastic, Terpene synthase 5, VacTPS5.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RLMF_PSYWF
Sequence: MTHPVTPKNTTRPTPANKPAASTLHPRNPHQGRYDFDKLIKALPELEKHAITNPSGEATINFSDADAVLTLNKALLAHHYNIKYWDLPKGYLCPPIPGRADYIHQVADLLNNNNSGSENKKPHVLDIGTGASLIYPIIGSQSYGWYFTATDIDPVSINTAKAICEINPNLKKLVTVKQQKNPKNIFKGIIGEHDYFDITVCNPPFHGSMQDVLDANNRKQSKLQKNRARRNPNGQANKFADAKNNLNFGGQNAELWTEGGEFSFISRMINESVGYAQQVNWFTTLVSRAENLKPLDALLRKVGARQIKTINMQHGQKASRILAWRFK
What is the function of this protein?
Specifically methylates the adenine in position 1618 of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase F, 23S rRNA mA1618 methyltransferase, rRNA adenine N-6-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL16/RlmF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_STAAR
Sequence: MKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIRTVRKTIARLKTVAREREIEQSKANQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: MTNN_STACT
Sequence: MIGIIGAMEEEILILKEKITDLEEISIAHVKFYKGYIDNQEVVLTLSGIGKVNAAISTTLLINTFSPDVILNTGSAGALDHSLNIGDVLISTEATYHDADATAFGYELGQIPNMPIAYAADDDLVTLAQSVVEQQEMNGKLGLIVSGDSFIGEVSQRETIKTNFPDAMAVEMEATAIAQTCYQFKVPFIITRAVSDLANGEANMTFDEFIGEAAKSSSEIVLEMLKSL
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: NDUS6_HUMAN
Sequence: MAAAMTFCRLLNRCGEAARSLPLGARCFGVRVSPTGEKVTHTGQVYDDKDYRRIRFVGRQKEVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHPKVYINLDKETKTGTCGYCGLQFRQHHH
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial, Complex I-13kD-A, CI-13kD-A, NADH-ubiquinone oxidoreductase 13 kDa-A subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS6 subunit family.
Protein: SYNG1_MACFA
Sequence: MDGIIEQKSMLVHSKISDAGKRNGLINTRNLMAESRDGLVSVYPAPQYQSHRVGASTVPASLDSSRSEPVQQLLDPNTLQQSVESRYRPNIILYSEGVLRSWGDGVTTDCCETTFIEDRSPTKDSLEYPDGKFIDLSADDIKIHTLSYDVEEEEEFQELESDYSSDTESEDNFLMMPPRDHLGLSVFSMLCCFWPLGIAAFYLSHETNKAVAKGDLHQASTSSRRALFLAVLSITIGTGVYVGVAVALIAYLSKNNHL
What is the function of this protein?
May regulate AMPA receptor content at nascent synapses, and have a role in postsynaptic development and maturation.
What are the official names of this protein?
Synapse differentiation-inducing gene protein 1, SynDIG1, Dispanin subfamily C member 2, DSPC2, Transmembrane protein 90B.
What is the protein family that this protein belongs to?
Belongs to the CD225/Dispanin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Early endosome membrane; Single-pass type II membrane protein. Postsynaptic density membrane. Synapse. Cell projection, dendrite. Cell projection, dendritic spine. Note=Shuttles between the cell surface and early endosome membrane.
Protein: ABDA_MANSE
Sequence: SNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARREREEQDRMKQQQQEKQAKLE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.  Required for segmental identity of the first through tenth abdominal segments.
What are the official names of this protein?
Homeobox protein abdominal-A homolog.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H1621_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGRADKEENRMEMQEKTEQGKSYLDFAENLLLQKLEELEAKLLEEDSEESRNSRQKRCIGEGVPCDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1a, U11-TRTX-Hhn1a, Hainantoxin-XVI.21, HNTX-XVI.21, Peptide F4-19.87.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YEAL_SHISS
Sequence: MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFPWIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ
What are the official names of this protein?
UPF0756 membrane protein YeaL.
What is the protein family that this protein belongs to?
Belongs to the UPF0756 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YA031_YEAST
Sequence: MKDMNSIRYVFFFFSRDIKSCFYKVRSYLNLLLILEAILCPVDSLISIPNGIMVVSEPDSPFSHSNPSRRLFRKVNPSSCLSVLYLDLCCSGLIIAEAGIGG
What are the official names of this protein?
Putative uncharacterized membrane protein YAL031W-A.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YR292_MIMIV
Sequence: MNYKDQLLKQMVDGKYDRKKYLNMYQRKYNLNSPKISTKPVTIDRARFLVKNKQENQTESSDLNNTDSLVDSNSDNQTNTTDTSTNNVENLNENVTEESTNDTNKDTNIETNNQTKILSPTKSFSPNKKVMDNVLKNQDKISDTERIRFLEEKVSKLERKIRTLSLQMTKISGRSNRFTDKSIKVGPKVYH
What are the official names of this protein?
Uncharacterized protein R292.