PharMolix/UniProtQA huggingface dataset:
Protein: LOLA_ACTP7
Sequence: MKKLLKQSLLGFALVSMTGAAFADAQSVAELQRRLEQVSQYSADFDQTVRSSKGKQIQSGKGKFQVKRPNLFRMDTKSPQENLIVSDGANLWFYDPFVSQVTVNTVQDAVNNTPFVLLTSSDKSHWDQYDVTQNADTFVLKPKSKKSNLKQFDVRIDQSGMLKGFSTIERDGQSNLYVLRNITGGGVSSDLFKFSVPKGAELDDQRGGKKSKK
What is the function of this protein?
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane.  Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
What are the official names of this protein?
Outer-membrane lipoprotein carrier protein.
What is the protein family that this protein belongs to?
Belongs to the LolA family.
What are the subcellular locations of this protein?
Periplasm.
Protein: HIS8_MYCTU
Sequence: MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVRLPYHLSSVTQAAARAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RL22_GEOMG
Sequence: MEARAKLSFARLSPRKTRLVVDMVRGRGIQDALTILRFSPQPSAKLVSKLLQSAVANAEQKGASDVDRLFVKTIFVDAGPVLKRFTPRAMGRASKIRKPTSHVTVVLADK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PYRF_CYBJA
Sequence: MVTTLSYTERASHPSPLAKRLFSLMESKKTNLCASVDVRTTEELLKLVDTLGPYICLLKTHIDIIDDFSMESTVAPLLELSKEHNFLIFEDRKFADIGNTVKAQYAGGAFKIAQWADITNAHGVTGRGIVKGLKEAAQETTDEPRGLLMLAELSSKGSFAHGTYTEETVEIAKTDKDFCIGFIAQRDMGGREDGFDWIIMTPGVGLDDKGDSLGQQYRTVDEVVSGGCDIIIVGRGLFGKGRDPTVEGERYRKAGWDAYLKRYSAQ
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase, Uridine 5'-monophosphate synthase, UMP synthase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family.
Protein: SIXA1_MESMA
Sequence: MKLFLLLLISASMLIDGLVNADGYIRGSNGCKVSCLWGNEGCNKECGAYGASYGYCWTWGLACWCEGLPDDKTWKSESNTCGGKK
What is the function of this protein?
Depressant insect toxins cause a transient contraction paralysis followed by a slow flaccid paralysis.  They bind voltage-independently to sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current (By similarity).
What are the official names of this protein?
Depressant insect toxin BmK ITa1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LLDD_SALCH
Sequence: MIISAASDYRAAAQRTLPPFLFHYIDGGAYAEYTLRRNVEDLSQVALRQRVLKNMSDLSLETTLFNETLPMPVALAPVGLCGMYARRGEVQAAAAADAKGIPFTLSTVSVCPIEEVAPTIQRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPTPGARYRDAHSGMSGPNAAMLRYWQAVMHPKWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLANNFDPSISWKDLEWIREFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAYLYALATAGKAGVANLLDLIEKEMKVAMTLTGAKTISEISGDSLVQELGKSLPAALAPMSKGDAA
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNZ_THEFY
Sequence: MSTRELIVLGTSSAVPTKRRAHNGYFLRWDGHGILFDPGEGTQRQMRYAGISAHDITRVCVTHFHGDHSLGLPGVIQRIARDGVTHPVRVAYPAAGQEYWERLRYATSFVDTEVIEAQPLAGDEVVVSGEDEFTVTALPLDHSIPTYGYRIAEPDRVHMLADRLAARGIRGPAVGRLKAEGFLIDAAGNRVELADYSVVRPGQVFAFVMDTGVCDTAVRLAERADLLVIEATFLNAEAELAARYRHLTAGQAGMIAAQAGVRRLVLTHFSERYGREEEDRFIAEAAACFSGEIVLAQDVMRVAVPSRRSEGGGTVAGA
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ASSY_MYCTO
Sequence: MSERVILAYSGGLDTSVAISWIGKETGREVVAVAIDLGQGGEHMDVIRQRALDCGAVEAVVVDARDEFAEGYCLPTVLNNALYMDRYPLVSAISRPLIVKHLVAAAREHGGGIVAHGCTGKGNDQVRFEVGFASLAPDLEVLAPVRDYAWTREKAIAFAEENAIPINVTKRSPFSIDQNVWGRAVETGFLEHLWNAPTKDIYAYTEDPTINWGVPDEVIVGFERGVPVSVDGKPVSMLAAIEELNRRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHTELEHVTLERELGRFKRQTDQRWAELVYDGLWYSPLKAALEAFVAKTQEHVSGEVRLVLHGGHIAVNGRRSAESLYDFNLATYDEGDSFDQSAARGFVYVHGLSSKLAARRDLR
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFYBA_ORYSJ
Sequence: MPDSDNESGGPSNAGEYASAREQDRFLPIANVSRIMKRALPANAKISKDAKETVQECVSEFISFITGEASDKCQREKRKTINGDDLLWAMTTLGFEDYIDPLKLYLHKFRELEGEKAIGAAGSGGGGAASSGGSGSGSGSHHHQDASRNNGGYGMYGGGGGMIMMMGQPMYGSPPASSAGYAQPPPPHHHHHQMVMGGKGAYGHGGGGGGGPSPSSGYGRQDRL
What is the function of this protein?
Component of the NF-Y/HAP transcription factor complex.
What are the official names of this protein?
Nuclear transcription factor Y subunit B-10, OsNF-YB10, Transcriptional activator HAP3F, OsHAP3F.
What is the protein family that this protein belongs to?
Belongs to the NFYB/HAP3 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DGK_BACSU
Sequence: MNTAPFIAIEGPIGAGKTTLATMLSQKFGFPMINEIVEDNPYLDKFYDNIKEWSFQLEMFFLCHRYKQLEDTSDHFLKKGQPVIADYHIYKNVIFAERTLSPHQLEKYKKIYHLLTDDLPKPNFIIYIKASLPTLLHRIEKRGRPFEKKIETSYLEQLISDYEVAIKQLQEADPELTVLTVDGDSKDFVLNKSDFERIAAHVKELIV
What is the function of this protein?
Plays an essential role in generating the deoxyribonucleotide precursors dGTP for DNA metabolism.  Highly specific toward deoxyguanosine (dGuo) and deoxyinosine (dIno).  Only marginal activity is observed with guanosine.  UTP is slightly more efficient as phosphate donor than CTP, ATP and GTP.
What are the official names of this protein?
Deoxyguanosine kinase, DGUO kinase, dGK.
What is the protein family that this protein belongs to?
Belongs to the DCK/DGK family.
Protein: BUK_DEIRA
Sequence: MSMIAHVINPGISGVKLACAVIEPGQNPAFPSHLQVSLTREELPLEAAPDELGLDALAERILEQTAAWPAPDAVVGRGGLMGRVPAGTYHVTPELARYVLENVSGSQPADDPNPGIGAPLALRVAQARGVPAYIVDPQSVDELLPEAHMTGVPGVRREARFHALNARAVARRAAYEVGKQFREARVVVAHLGVTTSVTAFDQGRAIDTTGTAPDGGPMGARQSGPLPTRAVIRLLQTQSESELLRLLTRGSGFFALTGTADLSEIERRQEQGEDSVVQTAIAAFVHQVCKAIGEQTAALPGRPDAVALTGGIARWDAVVDRIERRLAWVAPFIVLPGELELEALAEGAGRVLLGLEGVREWTPEGVTLRPAAPLVQVETVEEV
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSCB_YERPB
Sequence: MDYFTLFGLPARYLIDGNQLTTRYQELQRQFHPDRFATQPERERLASMQQAATINDAYQTLKHPLKRAEYMLSLQGFDLGNEQHTMRDTAFLMEQLELREELDAIERKPDAETLLAEFSRRLAQMTTTRTQQMVEQLDAQLWVQAADTVRKLRFLDKLQQQVEQLEERLFDDFA
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB, Hsc20.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: CNOT6_XENLA
Sequence: MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSSSLWSLTHLTALHLSDNSLSCIPSDIAKLHNLVYLDLSHNQIQSLPAELGNMVSLRELHLNYNQLRVLPFELGKLFQLQTLSLKGNPLTQDILNLCLEPDGTRRLLNYLLDNLSVSTEQPPPRSWIMLQEPDRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIISLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKELIEMSSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRSLKSSVLGECGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHKDFKELRYNESLTNFSCNGKNGMTNGRITHGFKLKSAYENGLMPYTNYTFDFKGIIDYIFYSKPQLNTLAILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR
What is the function of this protein?
Poly(A) nuclease involved in mRNA decay.  Has 3'-5' RNase activity (PubMed:20634287).  The CCR4-NOT complex functions as general transcription regulation complex (By similarity).  Enhances ligand-dependent transcriptional activity of nuclear hormone receptors (By similarity).
What are the official names of this protein?
CCR4-NOT transcription complex subunit 6, Cytoplasmic deadenylase.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: MTC1_PBCVC
Sequence: MKPIVKWSGGKTDELKRFEDYIPSDCSTFIEPFAGGAATFFHVGNQFENKVLSDVHVELVALYRAIANGKSQAIYDFMKSHANDEKTYYEVRSWKPEDYVDVASRFYYLRKTCFRGMMRYNKNGGFNVPFGRYKTYNFEDIINEEYYNILKDTIILEKSFDYIFETYNDSSNFVFLDPPYDSVFTDYGYCSFGKEEHVRLSNFFKTTKNKCLMVIGATDFIRELYDGYIHTEYEKKYRFKLHSGRVGDEINTTHLVIKNY
What is the function of this protein?
A alpha subtype methylase, recognizes the double-stranded sequence 5'-GANTC-3', methylates A-2 on both strands, and protects the DNA from cleavage by the CviBI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.CviBI, M.CviBI, Adenine-specific methyltransferase CviBI, Modification methylase CviBI.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: TPM3_BOVIN
Sequence: MEAIKKKMQMLKLDKENALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKAADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLEDELYAQKLKYKAISEELDHALNDMTSI
What is the function of this protein?
Binds to actin filaments in muscle and non-muscle cells.  Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction.  Smooth muscle contraction is regulated by interaction with caldesmon.  In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.
What are the official names of this protein?
Tropomyosin alpha-3 chain, Gamma-tropomyosin, Tropomyosin-3.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
What are the subcellular locations of this protein?
[Isoform 2]: Cytoplasm, cytoskeleton.
Protein: DAPE_RICPR
Sequence: MYTHYLKNLVSFKSVTPNSAGAIEYIDDLLKQHSFKTEIKIFGDSKKEQVTNLYAIFGGNEPNICFVGHVDVVPAGNYEFWHNSNPFKFHEQDGKIYGRGTVDMKGAIACFLAASLNFIKNNTDFKGSISFLITSDEEGKSKHGTKEMLQYIYDQRYKIDFAVVGEPTCEKEIGDTIKIGRRGSVNFKLNIVGLAGHVAYPHKANNPLPCLIKILNELINIKLDEGTEFFQNSNLEVTNIDVDNDTSNTIPASAAAHFNIRFNSLHNVETLRQLIEQIIKQYCKEYKVDYKLEYSSSAESFIQNPNDNDKIKKFANVIERTLKIKSKFSTSGGTSDARFVKDYCSLVEFGLLSDMAHKINEYTKISDLQKLYNVYYNFLIEIL
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: TRMD_VIBPA
Sequence: MWVGVISLFPEMFRSVTDFGVTGQAVKKGLLSIETWNPRDFTHDKHRTVDDRPYGGGPGMLMMVQPLRDAIHTAKKASPGKTKVIYLSPQGRKLDQKGVEELATNENLLLICGRYEGVDERIIQSEVDEEWSIGDFVMTGGEIPAMTLIDSVSRFIPGVLGDFASAEEDSFANGLLDCPHYTRPEVLDDKEVPSVLMSGNHKDIRQWRLKQSLGRTWLRRPELLENLALTDEQEQLLAEFISEHNAK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLF15_ARATH
Sequence: MGMSKSIKVIVSLALILFLALAATKVEATRYISYRGMNHGDHAIHCDKAHPNTCKKQVANPYRRGCGTIERCRRDTGRK
What is the function of this protein?
Cell signaling peptide that may regulate plant stress, growth, and development.  Mediates a rapid alkalinization of extracellular space by mediating a transient increase in the cytoplasmic Ca(2+) concentration leading to a calcium-dependent signaling events through a cell surface receptor and a concomitant activation of some intracellular mitogen-activated protein kinases (By similarity).
What are the official names of this protein?
Protein RALF-like 15.
What is the protein family that this protein belongs to?
Belongs to the plant rapid alkalinization factor (RALF) family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3392_ACISJ
Sequence: MPFDARTRPLTAPQARVLATLLEKSRTVPDSYPLTLNSLLAGCNQKSSRDPVMQLTESEVQQALDELRQQTLVLEIGGARVARWEHNFTRGVGVPDQSAALLGLLMLRGPQTAGELRINAERWHRFADISSVEAFLDELQSRSDDKGGPLVTLLPRAPGAREPRWAHLLCGPVDASLAQMASASPASRSEEDGALAQRVQALEDEVAALRATVQRLCEQLGVAEH
What are the official names of this protein?
UPF0502 protein Ajs_3392.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: PGES2_BOVIN
Sequence: MAHAVRALWPHGRALAWRLGDRPALGLHAQSRAGFTGAAGGSGPAATARKGGPRLLGAAALALGGALGLYHTARWHLRAQDLRAERSATQLSLSSRLQLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVPIVMAQEGESLQQLNDSSVIISALKTYLVSGQPLADIITYYPPMKAVNDQGKEVTEFCNKYWLMLDEKEAQRMYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPAEALASFDYIVKEGNFGTVEGAMAKYMGAAAMYFISKRLKRRHHLRDDVREDLYEAANKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLEAFDDLMRHTHIQPWYLRVEKAIAEAPQ
What is the function of this protein?
Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro) (PubMed:10446427, PubMed:11866447).  The biological function and the GSH-dependent property of PTGES2 is still under debate (By similarity).  In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA) (By similarity).
What are the official names of this protein?
Prostaglandin E synthase 2, Membrane-associated prostaglandin E synthase-2, mPGE synthase-2, Microsomal prostaglandin E synthase 2, mPGES-2.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily.
What are the subcellular locations of this protein?
Microsome membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Prostaglandin E synthase 2 truncated form]: Cytoplasm. Note=Synthesized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form.
Protein: UTP25_UNCRE
Sequence: MAVKGAAKGRGPPRRKQPRFETSRVQDLDDREPLNGEQVVSEDALNEASDAEYSVSSSDNEEEEKSTDKPYNVLLQLLNASEDSIGPAKKKRKLKHKEKNVKQQTEATKEASPGKGDLDLQDDLDVKEAENTESDNEQVENDEAEGSEDEADSGSDPFEIHFSQPDEAQLSKRIEATSQKWRTSRQTLPAGMRFTAVYPDVGEEQNLHRASLHSPKDLTLKRKLSEAASVHLPQFDAPNTSVAPYLFGYYDMIYGGRTTGNAAKLRDMYCLHALNHIIKTRDRVIKNNARVPKEGEDIEIRDQGFTRPKVLIILPTRQACVRVVDSISKFYQAEQQENRKRFMETFSTADDDTWEDKTEDFRELFGGNDDDMFRLGLKFTRKTVKFFSQFYSSDIILASPLGLRTAIEKEDGKKIEYDFLSSIELVIVDHADALLMQNWDHVEYIFSHLNLQPKEAHGCDFGRVRTWYLDGNAKYLRQTLILTSFITPEINSLFSHHAYNVFGKIKIDSTYPGAILDVPVPVPVRQTFSRFDSLSPVKDPDARFKYFTSTVLSSLAKNWSSSGKSSAAGTLIFIPSYLDFVRIRNYFATSSQTTNLSFGAISEYSSPRDVARARSHFMNGRHTVMLYTERLHHFRRYKIRGVKRVVMYGVPENPVFYKEIAGFLGIDPAAVGEAAEKGVRALFSKWDALKLERIAGTKRMGSMMLEKGGDTFTFT
What is the function of this protein?
DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 25, U3 snoRNA-associated protein 25, U three protein 25.
What is the protein family that this protein belongs to?
Belongs to the UTP25 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NAA40_SCHPO
Sequence: MHFLKQYLFYSPRRMKTQEIKNVTLEDVDFLKNLGVWVEIYHHLEKGLLQQCFNLVKKNMEALYRQSSFGWDDSEKLKEMEMEKLEYICIFEKTSKKLVGFLSFEDTVEAGLTCLYIYEIQLDEHIRGRNVGKWLLKNASILAYRRNLKYIFLTVFSANLNALNFYHHFDFVPHESSPQEKKFRSGKVIHPDYYILYTKSRKDW
What is the function of this protein?
N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A.
What are the official names of this protein?
N-alpha-acetyltransferase 40.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. NAA40 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: APAF_CANLF
Sequence: ILKKDNYSYISFYNALIHEGYKDLAALLHSGIPVISSSNGGKDSVGGITS
What is the function of this protein?
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase 9 (Apaf-3), leading to the activation of caspase-3 and apoptosis.  This activation requires ATP (By similarity).
What are the official names of this protein?
Apoptotic protease-activating factor 1, APAF-1.
Protein: RNPH_THISH
Sequence: MRPSGRQPDQLREIRFTRRFTKHAEGSVLVEFGDTRVLCTASVDDRTPPWLRNKGSGWVTAEYGMLPRSTHERMAREAARGKQGGRTQEIQRLIGRSLRAAVDLEGLGERQITVDCDVLQADGGTRTASISGGYVALHDAITHLMKQGKLKRNPLFGAVASVSVGIYQGVPVLDLDYAEDSNAETDMNVVMNDANAFIEVQGTAEGHAFRMDELNSMLALAQSGIQDIIAAQRAALEQG
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RSMH_RICCN
Sequence: MIQSHVSVMLNEMLEALSPKAGESYLDCTFGAGGYSKAILESCNCYVTALDRDPNVIKRAEEIQQHYGERFDFVETNFADSFAKLKEKKFDGIVLDLGVSSMQLDIADRGFSFLHDGPLDMRMSGQGLSAEEFVNAAEEKELADVIYKYGDESFSRRIAKRIVEYRKTARIDSTSKLAEIVRSSIGFRKGKIDPATKTFQAIRIYVNDELGELEQFLVNVKNILKKDGRLVVVSFHSLEDRIVKNFFKENSEKPVVRSKYAKDDMTIDPNKWLKIITNKALAPSDKEVGLNIRARSAKLRAAKAIYE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH101_VIBVY
Sequence: MNIRPLHDRVIVERQEVESKSAGGIVLTGSAAEKSTRGVVLAVGKGRILENGTVQPLDVKVGDTVIFAESYGTKTEKIDGKEVLIMSENDIMAIVD
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES 1, 10 kDa chaperonin 1, Chaperonin-10 1, Cpn10 1.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HFQ_LEGPL
Sequence: MSKNHLLQDPFLNELRKEKVPVSVFLVNGIKLHGIIDSFDQYVVMLKNSITQMVYKHAISTVVPSRMVKIPAEESSGEEEGTVAD
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: DCD_METI4
Sequence: MGVHSDDWIRQMVKKHRMIEPFEESQVRKKVDGSQVISFGLSSYGYDLRVSREFKIFTNVFNSVVDPKAFDPRSFVEMESDCCIIPPNSFALARSVEYFRIPRDVITICLGKSTYARCGIIVNVTPFEPEWEGYATLEISNTTPLPAKVYAEEGLAQVIFIQASEPCSISYAERNGKYMYQKGVTVPRL
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CYB_MYODS
Sequence: MTNIRKSHPLMKIINSSFIDLPAPSNISSWWNFGSLLGICLALQILTGLFLAMHYTSDTATAFNSVTHICRDVNYGWILRYLHANGASMFFICLYLHVGRGLYYGSYMYTETWNVGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISAMVMVHLLFLHETGSNNPTGIPSNMDMIPFHPYYTIKDILGLLLMIMALLMLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILIIIPLLHTSKQRSMAFRPLSQCLFWLLVADLLTLTWIGGQPVEHPYVIIGQLASILYFSIIIILMPLTSLVENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.