PharMolix/UniProtQA huggingface dataset:
Protein: ICP0_BHV1J
Sequence: MAPPAAAPELGSCCICLDAITGAARALPCLHAFCLACIRRWLEGRPTCPLCKAPVQSLIHSVASDECFEEIPVGGGPGADGALEPDAAVIWGEDYDAGPIDLTAADGEASGAGGEAGAADGSEAGGGAGGAEEAGEARGAGAGRAAGAAGGRAGRGADAAQEFIDRVARGPRLPLLPNTPEHGPGAPYLRRVVEWVEGALVGSFAVTARELAAMTDYVMAMLAECGFDDDGLADAMEPLIGEDDAPAFVRSLLFVAARCVTVGPSHLIPQQSAPPGGRGVVFLDTSDSDSEGSEDDSWSESEESSSGLSTSDLTAIDDTETEPETDAEVESRRTRGASGAARARRPAERQYVSTRGRQTPAVQPAPRSLARRPCGRAAAVSAPPSSRSRGGRRDPRLPAAPRAAPAAQARACSPEPREEGRGAGLGVAAGETAGWGAGSEEGRGERRARLLGEAGPPRVQARRRRRTELDRAPTPAPAPAPAPAPISTVIDLTANAPARPADPAPAAAPGPASAGAQIGTPAAAAAVTAAAAAPSVARSSAPSPAVTAAATSTAAAISTRAPTPSPAGRAPAADPRRAGAPALAGAARAEVGRNGNPGRERRPASAMARGDLDPGPESSAQKRRRTEMEVAAWVRESLLGTPRRSSAALAPQPGGRQGPSLAGLLGRCSGGSAWRQ
What is the function of this protein?
Evades nuclear antiviral defenses triggered by dsDNA viruses.  Acts during the initial stages of lytic infection and the reactivation of latent viral genome.  Prevents the antiviral effect of nuclear bodies by degrading host PML and SP100.
What are the official names of this protein?
E3 ubiquitin-protein ligase ICP0, IER 2.9/ER2.6, P135 protein, RING-type E3 ubiquitin transferase ICP0.
What is the protein family that this protein belongs to?
Belongs to the simplexviruses ICp0 family.
Protein: TES_CHICK
Sequence: MDLESKVKKMGLGHEQGFGAPCLKCKDKCEGFELHFWRKICRNCKCGQEEHDVLTSNEEDRKVGKLFEDTKYTTLIAKLKNDGIPMYKRNVMILTNPVPAKKNISINTVTYEWAPPVQNQTLARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPNEVKQMEQFVKKYKNEALGVGDVKLPGELETKATDKNNVNSGDRSTSAAVGAMEDKSADQKASQYSCYRCKLNMKEGDPAVYAERAGYDKLWHPACFVCCTCSELLVDMIYFWKNGNLYCGRHYCDSEKPRCAGCDELIFSNEYTQAEGQNWHLKHFCCFDCDCVLAGEIYVMVNDKPVCRPCYVKKHAAICQGCHNAIDPEVQRVTYNNFNWHATQECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  May play a role in the regulation of cell proliferation.  May inhibit cell growth (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: FTSK_STAAW
Sequence: MAQAKKKSTAKKKTTSKKRTNSRKKKNDNPIRYVIAILVVVLMVLGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLATGFITYSKRIPKTRRTAGSIVLQIALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLISLFGVCIITILLLCSSVILLTNHQHREVAKVVLENIKAWFGSFNEKMSERNQEKQLKREEKARLKEEQKARQNEQPQIKDVSDFTEVPQERDIPIYGHTENESKSQSQPSRKKRVFDAENSSNNIVNHHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSYVVPPLTLLNQPAKQKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLHNDIALALAAKDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGRDISGDPITVPLNEMPHLLVAGSTGSGKSVCINGIITSILLNAKPHEVKLMLIDPKMVELNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNELIRKQNQELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSVDVITGIIKNNIPSRIAFAVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQGAFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMKSEDALYDEAYLFVVEQQKASTSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: KDPA_ECOL6
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFSALGVSDREMNWKQYLSAILGLNILGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLAPVALLIALFFIQQGALQNFLPYQAVTTIEGSQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGDRRQGRMLLWAMSVIFVICTGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLALCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KATG_ASPOR
Sequence: MADKCPFHNQAPKPNVAGSGTQNRDWWPDQLKLNILRQHTTVSNPLDPDFDYAAAFNSLDYYALKKDLQDLMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRTFDGRGGGGQGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGNKISWADLMILTGNVALESMGFKTFGFAGGRKDTWEADESVYWGGETTWLGNDVRYSHGFAGSSKHGAVIADEASHRDIHSRELEKPLAAAHMGLIYVNPEGPDGNPDPVAAARDIRTTFARMAMNDEETVALIAGGHTFGKTHGAASSDHVGSEPEAAGLEAQGLGWQNSHGSGKGAHTITSGLEVTWTKTPTQWNLNFLEYLFRFEWVLTKSPAGANQWVAKDADAFIPDAYDSSKKHRPQMLTTDLSLRFDPAYEKISRRFLENPDQFAEAFARAWFKLTHRDMGPRARYIGPEVPAEELSWQDPIPAVNHPVISETDIAALKRDILATGVDPSKFISTAWASASTFRGSDKRGGANGARIRLAPQRDWEVNNQPWLAAALKALEDIQDKFNSAQNDGKRVSLADLIVLAGCAAVEKAASDAGHIITVPFTPGRMDASQDQTDVESFNQMEPVADGFRNYGTSTARVPAEHYLVDKAQLLTLSAPEMTVLVGGLRALNANYDGSAHGVFTTRPGQLTNDFFVNLLDMNTSWKASGSGNDIYEGTDRRTGSKKWTATRADLVFGSHAELRAIAEVYGSSDGKGKFVKDFVAAWAKVMNLDRFDVN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_CUPPJ
Sequence: MNDINPAFVMPDVQSSRDTRQIPIQRVGVKGVRYPVSLKTPAGVVPSVGTFNLDVHLPAEVKGTHMSRFVALLEEERAPLELASFRVLLDKMLEKLEAEAGRIEVTFPYFISKIAPVSGVESLMDYEVTLTGEIRNGVTRVFLKALVPVTSLCPCSKKISQYGAHNQRSHITMNVELAGELPVEALVRMAEEEASCELWGLLKRPDEKFVTERAYENPKFVEDLVRDIAMRLNADERIVAYVLEAENFESIHNHSAYAVIERDKRLEPTA
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: FADB_PSE14
Sequence: MIYEGKAITVKALESGIVELNFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVDNFKLPEAELVAGNLQANRIFSDFEDLGVPTVVAINGIALGGGLEMCLAADYRVISSSARIGLPEVKLGLYPGFGGTVRLPRIIGADNAIEWIASGKESSAEDALKVGAVDAVVAPEKLQAAALDLIQRAISGEFDYKAKRQPKLDKLKLNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKAANFGRDKALEIEAAGFVKMAKTSAAQSLIGLFLNDQELKKKAKGYDAVAKDVKQAAVLGAGIMGGGIAYQSAVKGTPILMKDIREEAIQLGLNEASKLLGGRLEKGRLTAAKMAEALNAIRPTLSYGDFGNVDLVVEAVVENPKVKQAVLAEVEANVGEHTILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSEEAVATTVAYARKMGKNPIVVNDCPGFLVNRVLFPYFGGFARLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRRSVVDALYEAKRLGQKNGKGFYAYETDKKGKPKKVNDPAVLDVLKPIVYEQREVSDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLIYGIGFPPFRGGALRYIDSIGVAEFVALADQYAELGALYQPTAKLREMASKGQSFFGQASSEE
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: PYRI_PHOV8
Sequence: MKMSDNKQALQVAALKNGTVIDHIPSDKLFTVVALLGLQDSDSNITIGNNFESKKLGKKGIIKVADRFFTDEEISRLSVVAPNVKLNIIRDYEVVEKKQVLMPEELRGIVKCANPKCITNNEPMTTLFHVIDKEHGILKCHYCEKEQSKEGIKLL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: ADNP_HUMAN
Sequence: MFQLPVNNLGSLRKARKTVKKILSDIGLEYCKEHIEDFKQFEPNDFYLKNTTWEDVGLWDPSLTKNQDYRTKPFCCSACPFSSKFFSAYKSHFRNVHSEDFENRILLNCPYCTFNADKKTLETHIKIFHAPNASAPSSSLSTFKDKNKNDGLKPKQADSVEQAVYYCKKCTYRDPLYEIVRKHIYREHFQHVAAPYIAKAGEKSLNGAVPLGSNAREESSIHCKRCLFMPKSYEALVQHVIEDHERIGYQVTAMIGHTNVVVPRSKPLMLIAPKPQDKKSMGLPPRIGSLASGNVRSLPSQQMVNRLSIPKPNLNSTGVNMMSSVHLQQNNYGVKSVGQGYSVGQSMRLGLGGNAPVSIPQQSQSVKQLLPSGNGRSYGLGSEQRSQAPARYSLQSANASSLSSGQLKSPSLSQSQASRVLGQSSSKPAAAATGPPPGNTSSTQKWKICTICNELFPENVYSVHFEKEHKAEKVPAVANYIMKIHNFTSKCLYCNRYLPTDTLLNHMLIHGLSCPYCRSTFNDVEKMAAHMRMVHIDEEMGPKTDSTLSFDLTLQQGSHTNIHLLVTTYNLRDAPAESVAYHAQNNPPVPPKPQPKVQEKADIPVKSSPQAAVPYKKDVGKTLCPLCFSILKGPISDALAHHLRERHQVIQTVHPVEKKLTYKCIHCLGVYTSNMTASTITLHLVHCRGVGKTQNGQDKTNAPSRLNQSPSLAPVKRTYEQMEFPLLKKRKLDDDSDSPSFFEEKPEEPVVLALDPKGHEDDSYEARKSFLTKYFNKQPYPTRREIEKLAASLWLWKSDIASHFSNKRKKCVRDCEKYKPGVLLGFNMKELNKVKHEMDFDAEWLFENHDEKDSRVNASKTADKKLNLGKEDDSSSDSFENLEEESNESGSPFDPVFEVEPKISNDNPEEHVLKVIPEDASESEEKLDQKEDGSKYETIHLTEEPTKLMHNASDSEVDQDDVVEWKDGASPSESGPGSQQVSDFEDNTCEMKPGTWSDESSQSEDARSSKPAAKKKATMQGDREQLKWKNSSYGKVEGFWSKDQSQWKNASENDERLSNPQIEWQNSTIDSEDGEQFDNMTDGVAEPMHGSLAGVKLSSQQA
What is the function of this protein?
May be involved in transcriptional regulation.  May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.  Positively modulates WNT-beta-catenin/CTNN1B signaling, acting by regulating phosphorylation of, and thereby stabilizing, CTNNB1.  May be required for neural induction and neuronal differentiation.  May be involved in erythroid differentiation (By similarity).
What are the official names of this protein?
Activity-dependent neuroprotector homeobox protein, Activity-dependent neuroprotective protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: NBPF1_HUMAN
Sequence: MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHSPCDSNQPHKNINITFEEDKVNSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDKPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKNEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASCSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMPKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYKSYSGTFHSLEEQQVCMAVDIGGHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGWALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEAVEPEVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSTKKRRRRGRKEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALDVDNRFLTLMGTSLHLVFQMGVIFPQ
What are the official names of this protein?
Neuroblastoma breakpoint family member 1.
What is the protein family that this protein belongs to?
Belongs to the NBPF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDAP2_BOVIN
Sequence: MDPLGAPSQFVDVDTLPSWGNSCEDQLNASEIAAETYQEETIRSPFLYNKDINGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLRGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETLEKVVFAVSELEEATYQKLLPLYFPRSLKEESRSLPCLPADIGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRRLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARENGPYYTSYLPSPDL
What are the official names of this protein?
Ganglioside-induced differentiation-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the GDAP2 family.
Protein: GLGB_DESVH
Sequence: MTIPCSRPLFIEPFDLYLFGMGRHRHLYRILGAHPAVQDGEAGYRFAVWAPNARSVHLSGDCNGWRHEGCPLFPVGVSGVWAAFVPGVRRGSLYKFVVRGADGRQEQKADPFALWAEMRPGVASVAWDIDNHAWGDGAWMAERARQGLPLERPVSIYEVHLGSWRRRHGDGHPFLTYDELGDQLIPYATGLGFTHLELLPVAEHPLDQSWGYQTGHYYAPTSRFGSPEGFKRFVDRCHQAGLGVILDWVPAHFPRDAWSLGRFDGTALYEHLDPRLGEHPDWGTYIFNYGRNEVRNFLTANALYWLREFHIDGLRMDAVASMLYLDYSREAGQWLPNRHGGRENLDAVDFLREVNTVIHAEFPGAMTLAEESTAWPGVSRPVYTGGLGFSFKWNMGWMHDTLGYLAEDPIHRAYHHGSLTFSMLYAFSENFVLPLSHDEVVHGKGALLSKMPGDMWQQQANLRLLYAYQWAHPGKKLLFMGGEFGQWNEWDESRELDWCLYRFPAHEGIARLVGDLNRLLRSEPAMHRRDHDWSGFRWVDFADYGSSVISFLRLAAGERPLLWIFNFTPVVRRFYRVPCPRGGTWRELCNTDSAYYGGSDVGNAGAVMAREDHWGGGHFIELTLPPLAAMCFAPVTGQGT
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: FPG_GLOVI
Sequence: MPELPEVETLRRDLLIHLPGERVVGVEVLRSDSVGYPADPAIFIEQMQGQIFSDRMLRRGKYLLLYFARGAALGVHLRMSGRLLWRCGEAPLEPHTRVRIPMASGHELRFEDMRVFGRLWLIPVGVPPERVMGGLTRLGPEPFAEMFDGPYLAGRFAGRNQPVKSALLDQQLVAGVGNIYADEALFSSGIHPALPVGGLDAAALERLHRAVVKVLEAGIAQRGATLRNYTDAQGINGNYAGTAWVYGRKGQPCRVCNTPIERIRLAGRSTHFCPTCQRAQQSVQ
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: LPXB_XANAC
Sequence: MKGIGNRESGIVDGQRNGASVGSVTTALPIPDSPLPIPGARKRAPRIALIAGEASGDILGAGLIEQLRLRYPNAEFVGIGGDAMRGVGCQTWFDASELAVMGLTEVLRHLPRLLKLRSAFRERVLAWKPDVFIGIDAPDFNLPVERWLKQRGIKTVHYVSPSVWAWREKRAEKIGVSADLVLCLFPMEPPIYAKHGVDARFVGHPMADDIAYQSDRAAARATLGLSASSTVLAVLPGSRHGEISRLGDTFFQAAWLVSEHLPNLHVLVPAANPGCKQLLAEQLSRSSLPVMRSHLLDGQARTAMLAADVVLLASGTATLEAMLVKRPMVVGYKVAPLTYRIVKLLGLLKVNRYALPNILANDDLAPELMQDDCTPERLCVALLDWFKHPDKVAALQPRYLALHAELRRDASARAADAVAGLLSQRESGMENRESAGAGA
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: KHSE_STAAT
Sequence: MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPNLCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGYYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRSLNSQVVSCHSELVDINISGVKERIVYQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIFK_THEKO
Sequence: MKKILMLIELSERNAIGRPVRITIRELADALNTSPQTVLRLLAELEDEGLIERKTEGRRTYIEILPKGLDFLQDICDKISNALSKGVIVGEVVSGLGEGAYYVRQYEPLIEEYLGFKPFPGTLNVKILFPKTVLDAVCNIRPVIIPGFVKDGRTFGDVKAYPVMIGGIKGAIVVPSRTIHPPRIAEIIAPVNLREALKLKDGDRVRLEVIQ
What is the function of this protein?
Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).
What are the official names of this protein?
Riboflavin kinase, RFK, CTP-dependent riboflavin kinase, CTP:riboflavin 5'-phosphotransferase, Flavokinase.
What is the protein family that this protein belongs to?
Belongs to the archaeal riboflavin kinase family.
Protein: DLK2_HUMAN
Sequence: MPSGCRCLHLVCLLCILGAPGQPVRADDCSSHCDLAHGCCAPDGSCRCDPGWEGLHCERCVRMPGCQHGTCHQPWQCICHSGWAGKFCDKDEHICTTQSPCQNGGQCMYDGGGEYHCVCLPGFHGRDCERKAGPCEQAGSPCRNGGQCQDDQGFALNFTCRCLVGFVGARCEVNVDDCLMRPCANGATCLDGINRFSCLCPEGFAGRFCTINLDDCASRPCQRGARCRDRVHDFDCLCPSGYGGKTCELVLPVPDPPTTVDTPLGPTSAVVVPATGPAPHSAGAGLLRISVKEVVRRQEAGLGEPSLVALVVFGALTAALVLATVLLTLRAWRRGVCPPGPCCYPAPHYAPACQDQECQVSMLPAGLPLPRDLPPEPGKTTAL
What is the function of this protein?
Regulates adipogenesis.
What are the official names of this protein?
Protein delta homolog 2, DLK-2, Epidermal growth factor-like protein 9, EGF-like protein 9.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: HIS4_RHOOB
Sequence: MSLVLLPAVDVVNGEAVRLVQGEAGSETGYGSPRDAALAWQNDGAEWVHIVDLDAAFGRGSNRELLADVVGELDVQVELSGGIRDDASLEAALATGCGRVNLGTAAIENPEWCARAIAKYGEKIAVGLDVRLVDGEYQLRGRGWVTEGGNLWETLARLDKDGCSRYVVTDVSKDGTLTGPNLELLAQVCAATDAPVVASGGVSTIDDLRAIAGLVDRGVEGSIVGKALYAGRFTLPEALAAVSG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBD28_ARATH
Sequence: MAEISGLPDDLLVKILAFLPTKVAISTSVLSKQWRFLWMWLPKLKYDDYDDITDGFNSVSAFQTYRDFIAKNLPLHRAPIIESLSLGFRCGTLQPEDLKSWVEVAVSRSVRELSILAYYRNNYALSSSSLYTCKSLVTLKGFNIRVDVPPTVCLLPSLRTLELKRVRYLNEDSLRMLLSFCPVLEYLSIERHDNDNLRGLVVDVPSLRRLSLTSYTGCSSDDYVIVTPSLKYFKAFDYRSEISSYKIEKIPELEEADISIERNPEKLFVYFKSIKCLSLQVDFNSKEEPGYDSGIVFNHLEELTPYINDANWSKLLFRLLNDSPKLRVLEISNSKSFYKEKIGEYLPVSWSKNQGSVPKCFLNSLETFRVKWYYSEEQEDRDFLSLIFKHARCLKSTSILHR
What are the official names of this protein?
Putative FBD-associated F-box protein At5g56690.
Protein: COX8B_THUOB
Sequence: VSAKPAKXXVTAGEQAIAMT
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 8B, mitochondrial, Cytochrome c oxidase polypeptide VIII-1, Cytochrome c oxidase subunit 8H.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIII family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: REBMT_LENAE
Sequence: MTESKSEGTAVAAPTPEEVRQMYDDFTDPFARIWGENLHFGYWEDAGADVSVDDATDRLTDEMIALLDVRSGDRVLDVGCGIGKPAVRLATARDVRVTGISISRPQVNQANARATAAGLANRVTFSYADAMDLPFEDASFDAVWALESLHHMPDRGRALREMARVLRPGGTVAIADFVLLAPVEGAKKEAVDAFRAGGGVLSLGGIDEYESDVRQAELVVTSTVDISAQARPSLVKTAEAFENARSQVEPFMGAEGLDRMIATFRGLAEVPEAGYVLIGARKP
What is the function of this protein?
Glycosyl O-methyltransferase that catalyzes the final step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid that inhibits topoisomerase 1.  Has broad substrate specificity and functions as glycosyl O-methyltransferase on a number of rebeccamycin analogs.
What are the official names of this protein?
Demethylrebeccamycin-D-glucose O-methyltransferase, Rebeccamycin O-methyltransferase, Rebeccamycin sugar 4'-O-methyltransferase RebM.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: ENPP6_HUMAN
Sequence: MAVKLGTLLLALALGLAQPASARRKLLVFLLDGFRSDYISDEALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGCEVEILGVRPTYCLEYKNVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHYGPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYISLNDLQQVKDRGPVVSLWPAPGKHSEIYNKLSTVEHMTVYEKEAIPSRFYYKKGKFVSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGPDFKSNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRASTAPPVWPSHCALALILLFLLA
What is the function of this protein?
Choline-specific glycerophosphodiesterase that hydrolyzes glycerophosphocholine (GPC) and lysophosphatidylcholine (LPC) and contributes to supplying choline to the cells (PubMed:15788404).  Has a preference for LPC with short (12:0 and 14:0) or polyunsaturated (18:2 and 20:4) fatty acids.  In vitro, hydrolyzes only choline-containing lysophospholipids, such as sphingosylphosphorylcholine (SPC), platelet-activating factor (PAF) and lysoPAF, but not other lysophospholipids (By similarity).
What are the official names of this protein?
Glycerophosphocholine cholinephosphodiesterase ENPP6, GPC-Cpde, Choline-specific glycerophosphodiester phosphodiesterase, Ectonucleotide pyrophosphatase/phosphodiesterase family member 6, E-NPP 6, NPP-6.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. Note=A small amount of the protein may be found in the extracellular milieu.