PharMolix/UniProtQA huggingface dataset:
Protein: CADC_ECOLI
Sequence: MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFWVWFFFLLSLGICVALVAFSSLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQKILPHRGALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKFLASE
What is the function of this protein?
Regulates the lysine- and pH-dependent expression of the lysine decarboxylase CadA and the cadaverine-lysine antiporter CadB (PubMed:1370290, PubMed:16491024, PubMed:18086202, PubMed:21216950).  At low external pH, and in the presence of external lysine, CadC activates transcription of the cadBA operon by binding directly to two sites, Cad1 and Cad2, within the cadBA promoter region (Pcad) (PubMed:16491024, PubMed:28432336).  Preferentially binds to AT-rich regions within the Cad1 promoter (PubMed:28432336).
What are the official names of this protein?
Transcriptional activator CadC, Membrane-integrated pH sensor CadC.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein. Note=Membrane insertion requires the SecA translocase.
Protein: CYRIA_PONAB
Sequence: MGNLLKVLTREIENYPHFFLDFENAQPTEGEREIWNQISAVLQDSESILADLQAYKGAGPEIRDAIQNPNDIQLQEKAWNAVCPLVVRLKRFYEFSIRLEKALQSLLESLTCPPYTPTQHLEREQALAKEFAEILHFTLRFDELKMRNPAIQNDFSYYRRTISRNRINNMHLDIENEVNNEMANRMSLFYAEATPMLKTLSNATMHFVSENKTLPIENTTDCLSTMTSVCKVMLETPEYRSRFTSEETLMFCMRVMVGVIILYDHVHPVGAFCKTSKIDMKGCIKVLKEQAPDSVEGLLNALRFTTKHLNDESTSKQIRAMLQ
What is the function of this protein?
May negatively regulate RAC1 signaling and RAC1-driven cytoskeletal remodeling.  May regulate chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions.
What are the official names of this protein?
CYFIP-related Rac1 interactor A.
What is the protein family that this protein belongs to?
Belongs to the CYRI family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: COAE_STRP1
Sequence: MIIGITGGIASGKSTVVKVIRKAGYQVIDADQVVHDLQEKGGRLYEALREAFGNQILKADGELDRTKLSEMLFSNPDNMATSSAIQNQIIKEELAAKRDHLAQSQAIFFMDIPLLMELGYQDWFDAIWLVYVDAQTQLQRLMARNRLDKGKARQRIASQLPIEEKKPYASLVIDNSGDIAALIKQVQSALLLLANPR
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_STRCO
Sequence: MGRLFGTDGVRGVANADLTAELALGLSVAAAHVLAEAGTFAGHRATAVVGRDPRASGEFLEAAVVAGLASAGVDVLRVGVLPTPAVAHLTGALGADLGVMLSASHNAMPDNGIKFFARGGHKLADELEDRIESVYADHRTGAPWDRPTGSGVGRVRDYDEGLDQYVAHLVGVLPNRLDGLKIVLDEAHGAASRVSPEAFARAGAELVTIGAVPDGLNINDGCGSTHLDLLKAAVVEHGADLGIAHDGDADRCLAVDHTGAEVDGDQILAVLALAMREREALRSDTVVATVMSNLGFKLAMEREGIRFVQTGVGDRYVLEEMKEHGYALGGEQSGHVIILDHATTGDGTLTGLMLAARVAQTGRTLRDLASVMERLPQVLVNVPDVDKSRVTSSAELATAVAEAERELGSTGRVLLRPSGTEPLVRVMVEAADIEQARSVAGRLADSVKSALG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: DXS_PROM9
Sequence: MLLSELSHPNELHGLTVSQLEEIACQIRERHLQVVSTSGGHLGPGLGVVELTLALYQTLDLDSDRVVWDVGHQGYPHKLITGRFSQFDSLRQQNGVAGYLKRSESKFDHFGAGHASTSISAALGMAIARDRKGENHKCVAVIGDGALTGGMALEAINHAGHLPNTPLVVVLNDNDMSISPPVGALSSYLNKVRLSPPLQFLSDSVQESVKNIPLIGKDIPEELKNIKGSVRRLAVPKVGAVFEELGFTYMGPIDGHDIENLINTFNAAHRLKKPVLVHIVTTKGKGYPYAEADQVGYHAQSAFDLTTGKSIPSKKPKPVSYSKIFGQTLLKICEQDSKVIGITAAMATGTGLDILQKNIPEQYVDVGIAEQHAVTLAAGMSCDGLKPVVAIYSTFLQRAFDQLIHDVGIQNLPVSFVLDRAGIVGADGPTHQGQYDISYMRSIPNFVLMAPKDESELQRMLITSINHKGPTALRIPRGSGLGVAVMDEGWEPLNIGEAEILEEGNDILIIAYGSMVASAIETAEILKGMNINTCIVNARFVKPLDKNLIIPLASRIQKVVTMEEGTLIGGFGSAIVELFNDNEVNIPVYRIGIPDVLVDHASPDQSKEKLGLMPDQMADKIIQKFKLNN
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: PPNP_SHESA
Sequence: MELIEQVSVAKKANIYFEGKVASRSVFFSDGSKKTLGVVLPGEYEFSTSQGEIMQVTSGSFEVLLPNSTTWQTFSEGSQFELAANVSFKIRNNAIAEYCCSYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: IDI1_GIBZE
Sequence: MSTTTTTTNQPITAESMLRLFPDIDTSSAPLSGHDEEQIRLMDEVCIVLDEDDKPIGTASKKICHLMTNIDKGLLHRAFSVFLFNDKNELLLQQRATEKITFPDMWTNTCCSHPLHIPTETGSTLEDSIAGVKRAAQRKLEHELGIKKEQVPFEDFHFLTRIHYKAPSDGMWGEHEIDYILFIKANVDLDINKNEVRDTQYVTPESLKQQFDDPSLVFTPWFKLICNSMLFEWWQNLDSGLDKYLNEQEIRRM
What is the function of this protein?
Isopentenyl-diphosphate delta-isomerase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway (By similarity).  IDI1 catalyzes the 1,3-allylic rearrangement of isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity).  The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.  Activity by the mevalonate kinase ERG12 (FG05912) first converts mevalonate into 5-phosphomevalonate.  5-phosphomevalonate is then further converted to 5-diphosphomevalonate by the phosphomevalonate kinase ERG8 (FG09764).  The diphosphomevalonate decarboxylase ERG19 (FG10424) then produces isopentenyl diphosphate.  The isopentenyl-diphosphate delta-isomerase IDI1 (FG09722) then catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).  Finally the farnesyl diphosphate synthase ERG20 (FG06784) catalyzes the sequential condensation of isopentenyl pyrophosphate with dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (Probable).
What are the official names of this protein?
Isopentenyl-diphosphate delta-isomerase IDI1, Ergosterol biosynthesis protein IDI1, Isopentenyl pyrophosphate isomerase IDI1, IPP isomerase.
What is the protein family that this protein belongs to?
Belongs to the IPP isomerase type 1 family.
Protein: RECX_PSESM
Sequence: MPAVLDTPVAIRRTAMDLLARREHGRVELTRKLRQRGAPPELIEAALDRLVEEGLLSESRYLESFVSYRARSGYGPARIREELNQRGLQRADVERALKECGVNWQEKLQEVWQRKFAGELPVDARERARQGRFLSYRGYPLDMIGRLLSGRGGDD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAUE_METFK
Sequence: MSWLINDPTAAVLASLFIGIVLAAAAIPKFRHPDEFQGVVANYKLLPSFLVAPVAKLLPLVELLCAVALMIPPAREIAACVAAGLFIVFALALAINVGRGRTHIDCGCVRRPTSMSRIGMFHVMRAIALAGVSLYVAAVPVEFSRISIESGLMGLAAAAMLALLYMGADMLVGFPNSKNDLLKGNTND
What is the function of this protein?
May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.
What are the official names of this protein?
Methylamine utilization protein MauE.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GRCA_HAEIN
Sequence: MIKGIQITQAANDNLLNSFWLLDSEKNEARCLCAKGEFAEDQVVAVSELGQIEYRELPVNVAPTVKVEGGQHLNVNVLRRETLEDAVNNPDKYPQLTIRVSGYAVRFNSLTPEQQRDVITRTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: SYK_BACC2
Sequence: MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNSTTDLVSLYGEFSKEELEEKEITVSIAGRIMTKRGKGKAGFAHIQDLHGQVQIYVRKDTVGDEEYELFTTADLGDLVGIEGKVFKTNVGELSVKATGFTLLTKSLRPLPDKYHGLKDVEQRYRQRYLDLITSMESRETFVTRSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFTTHHNALDMELYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYNDIMKLTENMVAHIAKKVLGTTTIQYGDYEINLEPEWTRLHMVDAIKQHSGADFWNPMSVEEARELAKEHNVEIKDTMEVGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDEDPRFTDRFELFIVAREHANAFTELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPAMRHKQD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S43A3_MOUSE
Sequence: MASKGLPLYLATLLTGLLECIGFAGVLFGWTSLLFVFKAENYFSEPCEQDCLLQSNVTGPSDLKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTTVARLIAIFFYTCATIIIAFTSANTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITLYNGAFDSSSAVFLVIKLLYEQGISLRSSFIFMSVCSVWHIARTFLLMPKGHIPYPLPPNYSYGLCSRFGASKKENKAAEHETKELRSKECLPPKEENSGPEQQQQQEQQQQQQQQQEQHEQHSFRRCALSRRFILHVVWLSIIQLWHYLFIGTLNSLLTKLSGGDKVEVSAYTNAFAITQFFGVLCAPWNGLLMDRLKQKYQKAAKRTGSSSEAVALCSMVPSLALTSLLSLGFALCASIPVMQLQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSAIVSLLQFPLFKVSPESNAVYVSMGLAIFLTLVHPFLVYRECRAEKTKSSVDA
What is the function of this protein?
Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (By similarity).  May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (PubMed:32217606).
What are the official names of this protein?
Equilibrative nucleobase transporter 1, Embryonic epithelia gene 1 protein, Solute carrier family 43 member 3.
What is the protein family that this protein belongs to?
Belongs to the SLC43A transporter (TC 2.A.1.44) family.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein.
Protein: Y4188_BRUSU
Sequence: MNARLTGLGLNLLSFAVGIGGWYLLTATGAVVLPGPVDVLERAVTLLLNGQLVGDIFASLRRVLSGFVLGVALAIPVGFLMGWYRIARSPIEPWVQFFRMIPPLAVIPLAIVTLGIDESPKIFVIFLASFLSSVVATYQGVISVDRTLINAARVLGAKDATIFARVIVPASVPFILVGVRIGLGSAWATVVAAELIAAQSGLGYRMQQAQLYYDLPTIFVSLVTIGILGLFMDRLLQAADRRLTQWQERA
What is the function of this protein?
Probably part of an ABC transporter complex.  Probably responsible for the translocation of the substrate across the membrane (Probable).
What are the official names of this protein?
Probable ABC transporter permease protein BRA1188/BS1330_II1179.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNB2_ADECR
Sequence: MSHKKVVAISESSSDEEVPVAPPTAPPKKRQRKAVEEPRGHQAMVEIARQATAALKARGDPGSIIVQTFCDQTVDVDKEGNVIFTPAKQKSICNKSGSPLASVASKIFKASEHKWQSAMEFALKVLNAYQVDHSKLTLLPDEGTLECFKKAVQAYITTSKMHVTYTFTNQKTFLHVAGRLLLDFVIKAAELAPGVNPSGCVVWQHGCQSSLMCLHGSPMIQKEQLVEMDVNSENAQRALKENPEKTKIVSNRWGRNVVQFKNEDAFCCSMDVNMSGGNFSGASCGMFYTDGPKAIMAFQQIMAFLKACYPSMPNAESHLLMPLKCECNWNSSLPLLGRQTCKITPFSLASANHIDKSEVDDQKMLATLNNPAMLVFQCCNPVYRNSKAAPQKNCDFKISSVDLVSCLQIAKQIWLSTVGEKPPVKFPEFHWSDEHRYQTTILPQGQHDDDLVLF
What is the function of this protein?
Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers.  Also enhances the rate of initiation.  Released from template upon second strand synthesis.  Assembles in complex with viral pTP, viral pol, host NFIA and host POU2F1/OCT1 on viral origin of replication.  Covers the whole ssDNA genome during synthesis.  The complementary strand synthesis induces its relese from DNA template.  May inhibit cellular transcription mediated by the interaction between host SRCAP and CBP.
What are the official names of this protein?
DNA-binding protein, DBP, Early 2A protein, Early E2A DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E2A DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Accumulates in infected cells.
Protein: KAD3_MOUSE
Sequence: MGASGRLLRAVIMGAPGSGKGTVSSRITKHFELKHLSSGDLLRQNMLQGTEIGVLAKTFIDQGKLIPDDVMTRLALHELKTLTQCSWLLDGFPRTLPQAEALDKVYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEAQTEPVLQYYQKKGVLETFSGTETNKIWPHVYSFLQTKVPETTQKASVTP
What is the function of this protein?
Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates.  Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
What are the official names of this protein?
GTP:AMP phosphotransferase AK3, mitochondrial, Adenylate kinase 3, AK 3, Adenylate kinase 3 alpha-like 1.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK3 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PSBL_SYNJB
Sequence: MADQPERNPNSQPVELNRTSLYLGLLLVFVVGLLFSSYFLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: PAF15_MOUSE
Sequence: MVRTKANYVPGAYRKAVASQAPRKVLGSSTFVTNSSSSSRKAENKYAGGNPVCVRPTPKWQKGIGEFFRLSPKESKKENQAPEEAGTSGLGKAKRKACPLQPDHRDDENE
What is the function of this protein?
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication.  Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions.  Also acts as a regulator of centrosome number (By similarity).
What are the official names of this protein?
PCNA-associated factor, HCV NS5A-transactivated protein 9 homolog, PCNA-associated factor of 15 kDa, PAF15, p15PAF, PCNA-clamp-associated factor.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Following DNA damage, localizes to DNA damage sites. Colocalizes with centrosomes in perinuclear region.
Protein: FTSH_MYCBO
Sequence: MNRKNVTRTITAIAVVVLLGWSFFYFSDDTRGYKPVDTSVAITQINGDNVKSAQIDDREQQLRLILKKGNNETDGSEKVITKYPTGYAVDLFNALSAKNAKVSTVVNQGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGKSRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPSRYQALGAKIPKGVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFEQAKQNSPCIIFVDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGDRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSKGKPMAADADLDGLAKRTVGMTGADLANVINEAALLTARENGTVITGPALEEAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTILARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTTGAVSDIEQATKIARSMVTEFGMSSKLGAVKYGSEHGDPFLGRTMGTQPDYSHEVAREIDEEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPELESIFADVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVPEPAFKAAIAQATQAAEAARSDAGQTGHGANGSPAGTHRSGDRQYGSTQPDYGAPAGWHAPGWPPRSSHRPSYSGEPAPTYPGQPYPTGQADPGSDESSAEQDDEVSRTKPAHG
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: AROC_COXBU
Sequence: MSGNSFGKLFTVTTAGESHGPALVAIVDGCPAGLSLTEADIQPDIDRRKTGKSRFTSQRRESDQVKILSGVFEGVTTGTPIALLIENADQRPRDYSQIKDLFRPGHGDYTYFKKYGFRDYRGGGRASARETVMRVAAGAIAKKYLREKVNLTIQGYTAAVGAIRAERIDLSAVEKNPFFFPDEVQIPHLEQLIMKLRRDGDSIGARLNVIAKGVPCGLGEPVFDKLDADIASAMMGINAVKGVEIGDGFAVVEQKGSFHRDELSKKGFLSNHAGGTLAGISSGQDILVSLAFKPASSIRIPGKTLDINGKAVEVVTTGRHDPCVGLRAVPIAEAMLALVLMDHYLRYKAQRG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: TRUB_SULDN
Sequence: MNRLFVAYKPAGIGSNLFLSRIKREYKTKKAGFSGTLDPFAKGVLIIGMGSYTKLFRFLAKAPKVYRATLWLGAKSDTLDTEMIEEVEILEEFDEADVLKAIKSLEGSLEYEPPIFSAKQINGQRAYDLARAGVEFSLNKINSTIYETKLVSYCHPFVTFEAIVSEGTYIRSLGLIIANRLGVKNGSLSALERLSEGRFKYDNHKPLDIKKSLNMMQNFYHGDSDNLKYGRVLALNDLEIKSDGFYWLDSGSFISIIHVKDAKVNYELGRIEC
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RNPA_RHIME
Sequence: MTTDKDKMAVGRLKSRPQFLAVRAGESRRGPLFLLEVLDRNDPEGEARVGFTVTKKHGNAVERNRMRRRLKEAVRLSAGFAMKPGHDYVIVARRDLLNAPFDALTRALRDRIENKPKQKRPPAGSRKS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: GRP_MOUSE
Sequence: MRGSELSLLLLALVLCQAPRGPAAPVSTGAGGGTVLAKMYPRGSHWAVGHLMGKKSTDESPSLYAADRDGLKEQLRGYVRWEEAARDLLDLLEAAGNQSHQPPQHPPLSLQPTWDPEDGSYFNDVQTAKLVDSLLQVLKEKGGTAS
What is the function of this protein?
Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
What are the official names of this protein?
Gastrin-releasing peptide, GRP.
What is the protein family that this protein belongs to?
Belongs to the bombesin/neuromedin-B/ranatensin family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle lumen. Cell projection, neuron projection. Note=In neurons of the retrotrapezoid nucleus/parafacial respiratory group, expressed on neuron projections which project into the pre-Botzinger complex.
Protein: RBL_LUPMC
Sequence: SVGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNQIIREASKWSPELAAACEVWKE
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YARQ_ACTPL
Sequence: MANPVKYESLIVVCNGLERLFGNIVKVISYPFHALFPKLRFTIPEYSPAKIKSKQNTRITKTIWQTNYSNKVTLPVYANYLFNRLMSLSYDYRYVSTEERETYIKENADTRTFNAYSKLTDGAAQADFWRVFTLLQEGGVYIDIDGHLVFPISQIIRENDQEVLIKRRDKYTNFFLACEERSPS
What are the official names of this protein?
Uncharacterized glycosyltransferase in aroQ 3'region, ORF3.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 32 family.
Protein: LRRC3_RAT
Sequence: MGPRGRQSPSSPLAPSQGSCFFILFCLRLGASCPQSCQCPDHAGAVAVHCSSRGLQEIPRDIPANTVLLKLDANRISRVPNGAFQHLPQLRELDLSHNAIEAIGPAAFSGLAGGLRLLDLSHNRIRRIPKDALGKLSAKIRLSHNPLHCECALQEALWELKLDPDSVDEIACHTSAQEQFVGKPLIQVLDSGASFCSTHRKTTDVAMLVTMFGWFTMVIAYVVYYVRHNQEDARRHLEYLKSLPSAPVSKEPLSPVP
What are the official names of this protein?
Leucine-rich repeat-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the LRRC3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YAJ1_SCHPO
Sequence: MLLFKFNFTTAFLFTILAFAQARSHSSSSSSTSKSSASHHSSINSTSATSVYDFSSLTTPIVPTNGVAQEPTLYESSRGLSCPGYQARNISEYSYGVLAILELAGDACYAYGTDYPYLLLNVSYDTEERVHISISDLNQTQFQLSNRRDVWDAPLFYRSSNFSGNLQYNFSFNTDPFEFWITRIADDQVLFDTRGNPLIFEDQYIELTTNMVEDYNVYGLSGSQQSFRLGNNLTKTFWATGYSDSPEANMYGSHPFYMEQRYIPIGTTNTYTSASHGVLMLSSNGMEVLLRSTYIKYRMIGGIIDLFVYSGSTVSPKYTIQQYVQSIGTPTMQPYWSLGFQMSRWGYKTLSDLINMRSYLNASNIPTEGFWNDIDYMSEFRTFTVNSTAFPPNQTLDFFRSLDESHQHYVPVLDPAIYAANPNKSADRTYYPYYSGFEDNIFIKNPNGSAYVGMAWPGFVVYPDFTNPAVLQYWKQGILNLSTAFGSNYSYDLPFSGLCLDMNEPTSFCIGSCGSDLLKLNPVHPPFSLPGDVDNKVYSYPEDFNATNTTEYKSVSRASQSQYKATATSEKSHETPSSESLINGKPEFSINYPPYALDTDTETHDLAQFGVSPNATMHGNTLRYNLFNTYGYSESKISFEALNSIQPNIRPFLLSRSTFVGSGRYAAHWLGDNKSQWSDMVSSISSILTFNLLGIPMVGADVCGYNGNTDEELCARWMALGAFLPFYRNHNSLGSIPQEPFRWASVAEASRSAIEIRYSLLPYWYTLMHTASVDGTPMVRPLFFEFPKQISLASVDKQFMIGTALLISPALEPNTTYIQGIIPGDNDTIWYDWYNHSVINHDYDENITMSAPLGYVNIAVRGGNIIPLQQPGYTTYESRNNPYSLLIAMDNNGFASGSLYIDDGISMQTNSSLSVKLNSNSNTITCVVSGTMVSSPSLANITILGLSNPPNTILFNGQQLSDYQYSDQTLSLTNLLDLTVDGAFSKNWTVTWS
What are the official names of this protein?
Uncharacterized family 31 glucosidase C30D11.01c.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.