PharMolix/UniProtQA huggingface dataset:
Protein: BIG1_RAT
Sequence: MYEGKKTKNMFLTRALEKILADKEVKKAHHSQLRKACEVALEEIKVETEKQSPPHGEAKAGSGTLPPVKSKTNFIEADKYFLPFELACQSKCPRIVSTSLDCLQKLIAYGHLTGSAPDSTTPGKKLIDRIIETICGCFQGPQTDEGVQLQIIKALLTAVTSQHIEIHEGTVLQAVRTCYNIYLASKNLINQTTAKATLTQMLNVIFARMENQALQEAKQMERERHRQQHHLLQSPVSHHEPESPHLRYLPPQTVDHIAQEQEGDLDPQTHDVDKSLQDDIEPENGSDISSAENEQTEADQATAAETLSKDDVLCDGECEEKPQDIVQSIVEEMVDIIVGDMGEGTAVSASADGNAGAVEDGSDSENVQANGIPGTPISAAYTPSLPDDRLSVSSNDTQESGNSSGPSPGAKFSHILQKDAFLVFRSLCKLSMKPLSDGPPDPKSHELRSKILSLQLLLSILQNAGPVFRTNEMFINAIKQYLCVALSKNGVSSVPEVFELSLSIFLTLLSNFKTHLKMQIEVFFKEIFLYILETSTSSFDHKWMVIQTLTRICADAQSVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRGSQELGMSNVQELSLRKKGLECLVSILKCMVEWSKDQYVNPNSQTTLGQEKPSEQEISEIKHPETINRYGSLNSLESTSSSGIGSYSTQMSGTDNPEQFEVLKQQKEIIEQGIDLFNKKPKRGIQYLQEQGMLGTTPEDIAQFLHQEERLDSTQAGEFLGDNDKFNKEVMYAYVDQHDFSGKDFVSALRLFLEGFRLPGEAQKIDRLMEKFAARYLECNQGQTLFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSAIYNEIAGKKISMKETKELTIPTKSTKQNVASEKQRRLLYNLEMEQMAKTAKALMEAVSHVQAPFTSATHLEHVRPMFKLAWTPFLAAFSVGLQDCDDTDVASLCLEGIRCAIRIACIFSIQLERDAYVQALARFTLLTVSSGITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKPRYISGTVRGREGSLTGTKDQAPDEFVGLGLVGGNVDWKQIASIQESIGETSSQSVVVAVDRIFTGSTRLDGNAIVDFVRWLCAVSMDELLSTTHPRMFSLQKIVEISYYNMGRIRLQWSRIWEVIGDHFNKVGCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKRNRSPTIRDMVVRCIAQMVNSQAANIRSGWKNIFSVFHLAASDQDESIVELAFQTSGHIVTLVFEKHFPATIDSFQDAVKCLSEFACNAAFPDTSMEAIRLIRHCAKYVSDRPQAFKEYTSDDMNVAPEDRVWVRGWFPILFELSCVINRCKLDVRTRGLTVMFEIMKTYGHTYEKHWWQDLFRIVFRIFDNMKLPEQQTEKAEWMTTTCNHALYAICDVFTQYLEVLSDVLLDDIFAQLYWCVQQDNEQLARSGTNCLENVVILNGEKFTLEIWDKTCNCTLDIFKTTIPHALLTWRPTSGEAAPPSPSAMSEKQLDAISQKSVDIHDSAQPRSSDNRQQAPLVSVSPASEEVSKGRPTAKFPEQKLFAALLIKCVVQLELIQTIDNIVFFPATSKKEDAENLAAAQRDAVDFDVRVDTQDQGMYRFLTSQQLFKLLDCLLESHRFAKAFNSNNEQRTALWKAGFKGKSKPNLLKQETSSLACGLRILFRMYTDESRVSAWEEVQQRLLNVCSEALSYFLTLTSESHREAWTNLLLLFLTKVLKISDNRFKAHASFYYPLLCEIMQFDLIPELRAVLRRFFLRIGIVFQISQPPEQELGINKQ
What is the function of this protein?
Promotes guanine-nucleotide exchange on ARF1 and ARF3.  Promotes the activation of ARF1/ARF3 through replacement of GDP with GTP.  Involved in vesicular trafficking.  Required for the maintenance of Golgi structure; the function may be independent of its GEF activity.  Required for the maturaion of integrin beta-1 in the Golgi.  Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing.  Proposed to act as A kinase-anchoring protein (AKAP) and may mediate crosstalk between Arf and PKA pathways.  Inhibits GAP activity of MYO9B probably through competitive RhoA binding.  The function in the nucleus remains to be determined (By similarity).
What are the official names of this protein?
Brefeldin A-inhibited guanine nucleotide-exchange protein 1, BIG1, Brefeldin A-inhibited GEP 1, ADP-ribosylation factor guanine nucleotide-exchange factor 1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Nucleus. Nucleus, nucleolus. Nucleus matrix. Membrane. Note=Translocates from cytoplasm to membranes and nucleus upon cAMP treatment (By similarity). PRKAR1B.
Protein: MAP2_YEAST
Sequence: MTDAEIENSPASDLKELNLENEGVEQQDQAKADESDPVESKKKKNKKKKKKKSNVKKIELLFPDGKYPEGAWMDYHQDFNLQRTTDEESRYLKRDLERAEHWNDVRKGAEIHRRVRRAIKDRIVPGMKLMDIADMIENTTRKYTGAENLLAMEDPKSQGIGFPTGLSLNHCAAHFTPNAGDKTVLKYEDVMKVDYGVQVNGNIIDSAFTVSFDPQYDNLLAAVKDATYTGIKEAGIDVRLTDIGEAIQEVMESYEVEINGETYQVKPCRNLCGHSIAPYRIHGGKSVPIVKNGDTTKMEEGEHFAIETFGSTGRGYVTAGGEVSHYARSAEDHQVMPTLDSAKNLLKTIDRNFGTLPFCRRYLDRLGQEKYLFALNNLVRHGLVQDYPPLNDIPGSYTAQFEHTILLHAHKKEVVSKGDDY
What is the function of this protein?
Cotranslationally removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Plays only a minor role in N-terminal methionine removal.  Less efficient when the second residue is Val, Gly, Cys or Thr.
What are the official names of this protein?
Methionine aminopeptidase 2, MAP 2, MetAP 2, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUON_ECO7I
Sequence: MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGIWPQPLISIVRLAMPLM
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CT141_HUMAN
Sequence: MTRLCLPRPEAREDPIPVPPRGLGAGEGSGSPVRPPVSTWGPSWAQLLDSVLWLGALGLTIQAVFSTTGPALLLLLVSFLTFDLLHRPAGHTLPQRKLLTRGQSQGAGEGPGQQEALLLQMGTVSGQLSLQDALLLLLMGLGPLLRACGMPLTLLGLAFCLHPWA
What are the official names of this protein?
Uncharacterized protein C20orf141.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: F16PA_BRUSI
Sequence: MTLVGNFSPLVLVGDSDRVEAETVGAYLDGWAGHDKVRLATANAIKAILSGAGRLVGRIARGYLPGDPGKLVGVNSDQDQQKSIDVGSHNLFVELLIAAGVASILSEEADLPVAGKADGLVAVAIDPLDGSGNVGLGAPLGTIFSIFPADVEEPFLQPGNRQIAAGYVSYGNSVDLGFSVGEGVIFATLDPVSGQFHITRRNVKLPERTSDLAFNASVQRHLSAGMQAYVNDAFLGKDGPRGRNFNMRWLGAAVGDMHRIMQRGGLFFYVNDSRPGYEKGRLRLVYEANPIAFLAREAGGKATDGSRPILDIVPQTYHERSALVFGVAEEVDILGEYFVK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1, FBPase class 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPP2_ARTOC
Sequence: MTSYSISVSVKGTNINKYPGKQHARRVAARLAKQKGLIYLPGQQTVLSEDSDQARPFKQRRYFFYVTGVVEPDCHVTYDIAEDKLTLYVPDFDFKRTIWTGPTLGKDDAKQRYDVDAVEYYSSLEGDVQRWAQGNPSTPIYILHPDQKPVTPLTVAYLYESKSLQHAMDACRVIKDEHESEAQIAGLFIDVCLSLRSRGTAYQTIAASGPNGATLHYTRNNEPLAGRQMVVLDAGAEWDCYASDVTRSFPIPSSVSGKENSGKGDWPSREAEEVYAIVQRMQEESISRVREGAMFFSIHQHAHSIALDELLRLGILRIPHGSSKADLVKAEATALFFPHGLGHHLGLEVHDVAPDSGTVPVTSSSSSSSSRVTAVTAQCQDGLMSVTEHRPPCTLSAPPLAAGMVITVEPGIYFNRLAIDQARAERDKPGSKGRFVDFDVVERYMAVGGVRIEDDVLVTKDGSRNLTDAPKGQDMLDMIYDRC
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase MCYG_06503, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: KTHY_FRATW
Sequence: MQSKFIVIEGLDGAGKSTAISFVRKYLEKNNLAAIYTREPGGTKIAEELRNLVLHNKYDEEIHSDSELLMIYAGRVQHYRNLIAPALEKGINVVSDRFYWSSMAYQGGGRGVELSKIRALNDNFLNGCEPDLVIYLDIDPILGLQRAQKVGSPDRIEKAGLEFFNRTRKVFKDLVKDSDNAIEIDAAKSIQEVEKQIYLILDKHFNFQN
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: TENR_MOUSE
Sequence: MGIDGETVVLKNMLIGVNLILLGSMLKPSECRLEVTTERAQRQTVEEEGGASSYNTSSKEQPMVFNHVYNINVPLESLCSSGLEASAEQDMSAEDDTLAEYIGQTSDHESQVTFTHKINLPKKACPCASSSQVLQELLSRIEMLEREVSLLRDQCNTNCCQESAATGQLDYVPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTIMELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVEWTPPRAKVDFILLKYGLVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESEASSTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDKEEDMLEVLLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKNITISNVTKDSLTVSWSSPVAPFDYYRVSYRPTQVGRLDSSVVPNTVTEFAITRLYPATEYEISLNSVRGREESERICTLVHTAMDSPMDLIATNITPTEALLQWKAPMGEVENYVIVLTHFAIAGETILVDGVSEEFQLVDLLPSTHYTVTMYATSGPLMSGTIATNFSTLLDPPDNLTASEVTRQSALISWQPPRAAIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTVFTTGGRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNIHRITAQGRYELRVDMRDGQEAVFAYYDKFAVEDSRSLYKIRIGSYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRPYIHRLTAGRKRRALKF
What is the function of this protein?
Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components.  Theses interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth.  Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment.  Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation.  Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth.  Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.  TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediates inhibition of cell adhesion and neurite outgrowth.  The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance (By similarity).
What are the official names of this protein?
Tenascin-R, TN-R, Janusin, Neural recognition molecule J1-160/180, Restrictin.
What is the protein family that this protein belongs to?
Belongs to the tenascin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: GLMM_RUEST
Sequence: MRKLFGTDGVRGKANMHPMTAEMALRIGAAVGRYFRRENDTVHRVVIGKDTRLSGYMFENALTAGLTSTGMNVLLLGPVPTPAVGLMTRSMRADLGVMISASHNPAEDNGIKFFGPDGYKLSDEVELELEALIEAGVEPAQAQNIGRAKRIDDARFRYGERVKSSLPRDMRLDGLKVVIDCANGAAHRAAPEILWELGADVIPVGVSPDGLNINRGCGSTQPAAAAETVVAHGADVGICLDGDADRVVVIDETGTVADGDQLMALLASAWSADGRLSGGALVATVMSNLGLERFLNERGIGLERTGVGDRYVVERMRQGGFNLGGEQSGHIVMSDYATTGDGLMAGLHFLAEMVRRGQKASELARQFEPVPQLLKNVRFEAGQAPLEADQVQTAIAEAEKQLNGRGRLLIRKSGTEPLIRVMAESEDPVLLNRAVDDVVAAVEAATQ
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: CHYE_PENRW
Sequence: MDSVSNLKIAVLINTPPDETDFQSVVRECFREAFASIAPTGEVDFYDPVVERKFPDASRYDLVVLSGGKIDAACSDPWVLGVLDYVRITARDLPKTKILAVCWGHQAVSRAFGGQVRPVPAGEITAIEDIRLTDAGMKFFPFAATSGSYRAIELHSGEVYTPPPGFISLAENQECFINDTNNVLTFQAHPEISHELASKLILEEDKKHSRNSSAEVLGIDRPTEGLKLLERVLQWLSE
What is the function of this protein?
Glutamine amidotransferase-like protein; part of the gene cluster that mediates the biosynthesis of the yellow pigment chrysogine (PubMed:29196288).  the NRPS chyA mediates the condensation of anthranilic acid and alanine into the intermediate 2-(2-aminopropanamido)benzoic acid (PubMed:29196288).  The remainder of the pathway is highly branched yielding at least 13 chrysogine-related compounds (PubMed:29196288).  The malonyl transferase chyE converts 2-(2-aminopropanamido)benzoic acid and 2-(2-aminopropanamido)benzamidine into 2-(2-(2-carboxyacetamido)propanamido)benzoic acid and 3-((1-((2-carbamoylphenyl)amino)-1-oxopropan-2-yl)amino)-3-oxopropanoic acid, respectively (PubMed:29196288).  ChyD is an amidase, being responsible for the amidation of the carboxylic acid moiety of 2-(2-aminopropanamido)benzoic acid, 2-(2-(2-carboxyacetamido)propanamido)benzoic acid and 2-(2-((4-amino-1-carboxy-4-oxobutyl)amino)propanamido)benzoic acid (PubMed:29196288).  ChyC is involved in the same reactions as ChyD, but plays a more minor role in the amidation reactions compared to chyD (PubMed:29196288).  The oxidoreductases chyH and chyM are involved in oxidation reactions that form N-pyruvoylanthranilamide from 2-(2-aminopropanamido)benzamidine and (1-((2-carbamoylphenyl)amino)-1-oxopropan-2-yl)glutamine, respectively (PubMed:29196288).  N-pyruvoylanthranilamide is further converted via two further branches in the pathway, yielding chrysogine and additional chrysogine-related coumpounds (PubMed:29196288).  Chrysogine is likely formed by a spontaneous ring closure from N-pyruvoylanthranilamide (PubMed:29196288).
What are the official names of this protein?
Glutamine amidotransferase-like protein chyE, Chrysogine biosynthesis cluster protein E, Malonyl transferase chyE.
What is the protein family that this protein belongs to?
Belongs to the peptidase C26 family.
Protein: PYRG_PSEF5
Sequence: MTRYIFVTGGVVSSLGKGIASASLAAILEARGLKVTMLKLDPYINVDPGTMSPFQHGEVFVTHDGAETDLDLGHYERFIRTTMTQNNNFTTGRVYEHVLRKERRGDYLGATIQVIPHITDEIKRRIIKGAGDADVALVEIGGTVGDIESQPFLEAIRQLRVEVGSKRAMLMHLTLVPYIATAGETKTKPTQHSVKELRSIGLQPDVLICRSDHPVDVSSRRKIALFTNVEERAVISLEDVDTIYKIPAVLHAQGLDDFVVERFGLQCNGADLSEWEKVVDAKLNPEHEVTIAMVGKYMELLDAYKSLIEAMSHAGITNRTKVNLRYIDSEDIENQGTALLEGVDAILVPGGFGLRGVEGKITAVQYARENKVPYLGICLGMQVAVIEFARNVMGWKDANSTEFDRTSGHPVVGLITEWEDATGAVEVRTEASDLGGTMRLGAQECLLEAGSKVHDCYAKDVIIERHRHRYEVNNKLLPQLIEAGLKISGRSGDGALVEVVEAQDHPWFVACQFHPEFTSTPRDGHPLFSGFVKAALAQHQKKA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TRM5_ANODA
Sequence: MCADLLPPATVRGMEQLDRDAFAKTVRVPHLIIPEATNLNSAARALKQYLLKMEHYKPIRSEERKITLHPIPVKQWEDLPVEPLKELGIEKDCLVWEEIKLSYENYKYDLILKAVLPENQEGLSAFSKIGHIIHLNLKNHLMPYRRLIGEVLMDKVADCRTVVNKSNSIQNTYRNFEMELICGVPEYEVSIKENGCTYKFNFSRVYWNPRLSTEHQKITDMLEEGDLLYDLYAGVGPFTVPAAKRGCTVIANDLNPDSYSALVINCGLNKVMRNVKCYNMDAVDFIKVELRNDLLAKLADDKFQGNIHITMNLPAMAVEHLVHFPGLFSGESIELRIKPLVHVYCFAQGADDKKPIAQQKVEQWLGVEVTDMLKEITFVRNVAPNKDMMRVRNPSALGMAKKANKLKDQPKQLAKKAKNVFAVSQTKKGNLKKTKEVAAKLKKINVQDKREKVDANFKTLHAQIVAKKTPKPAPRPLPAKNKTTPDTNKMETDLTKLEMK
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: NH2L1_MACFA
Sequence: MTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRPVIACSVTIKEGSQLKQQIQSIQQSIERLLV
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in pre-mRNA splicing as component of the spliceosome.  Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly.  The protein undergoes a conformational change upon RNA-binding.
What are the official names of this protein?
NHP2-like protein 1, High mobility group-like nuclear protein 2 homolog 1, U4/U6.U5 small nuclear ribonucleoprotein SNU13, U4/U6.U5 tri-snRNP 15.5 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Note=Concentrated in the dense fibrillar component of the nucleolus.
Protein: PABP_ASHGO
Sequence: MSDITDKTAEQLEQLKIEEQTAPTTTESETPKVETSGASLYVGELEPTVSEALLYDIFSPIGSVSSIRVCRDAITNTSLGYAYVNFHDHEAGPKAIEQLNYTLIKGKPCRIMWSQRDPSLRKKGSGNIYIKNLHPAIDNKSLHETFSTFGNILSCKVATDENGVSRGFGFVHFENESDARDAIEAVDGMLMNDQEVYVALHVSKKDRQSKLEEVKAKFTNVYVKNIDQETSQEEFEELFGKYGKITSAVLEKDSEGKLRGFGFVNFEDHAAAAKAVDELNELEFKGQKLYVGRAQKKYERLQELKKQYEAARLEKLAKYQGVNLFVKNLDDSIDDEKLKEEFAPFGTITSAKVMRDETGNSRGFGFVCFSTPEEATKAITEKNQQIVAGKPLYVAIAQRKEVRRNQLAQQIQARNQMRFQHANAAAAAAVAGLPGQFMPPPMYYGGIPPRVPFQGPNPQMAGMPKNGAMPPQQFGRPGPMYGGFAPQGQFPRNGQQQQFYQQKQRQALGEQLYQKVFAKTQDDEAAGKITGMILDLPPQQVIQLLENDELLEQHFQEAHAAYQKFKEDQEAQAAAAAAAAADARE
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.  In the nucleus, involved in both mRNA cleavage and polyadenylation.  Is also required for efficient mRNA export to the cytoplasm.  Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation.  In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein, cytoplasmic and nuclear, PABP, Poly(A)-binding protein, Polyadenylate tail-binding protein.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL9_CERS4
Sequence: MQVILLQRVAKLGQMGEVVNVKDGYARNFLLPQGKALRANESNIKSFEARKAQLEAQNLETKKEAAAVAEKLDGQSFVVIRSASDSGALYGSVTTRDAAEAATEAGFTVGRGQIVLDRPIKDLGLHTVTVTLHPEVVVKITLNVARSVEEAELQASGKSIQELAAEAEAAADFEIAELFDEIGAASQED
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: TOLB_CHLT2
Sequence: MKGSVVFLRSLLCLLCLLPSTLHCEDLEIHVRSESSLLPIAVSLLSSPKDSRQASYLASLRDLFARDLALGDLLAPTKELAPQTIFIEASYPELIFSLKKEGKGSQKIFSLELSGDPSKDHQAIHEAADRIHFLLTRVPGISSGKIIFSLCATNSSTELKQGELWSVDYDGQHLYPLTNEHSLSVTPTWMHISHIPAYMYVSYKLGVPKIFLNTLNQPAGKKILAMQGNQFMPTFSPKTKLLAFISDRDGNPDLFVQSFSLATGAIGTPKKLLNEAFGTQGNPSFSPDGTRLVFVSNKDGTPRIYQMQISPEQHSPRLLTKKYRNSSCPTWSPDGKKIAFCSVIKGVRQICVYDLASGRDEQLTTSTEHKESPSWAADSNHLVYSAGSSNTSELFLLSLITKKSRKIVIGSGEKRFPCWGAFPSQHIKKTS
What are the official names of this protein?
Protein TolB homolog.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: STAD5_ORYSJ
Sequence: MAFAASHTASPSSCGGVAQRRSNGMSPVVAMASTINRVKTAKKPYTPPREVHLQVKHSLPPQKREIFDSLQPWAKENLLNLLKPVEKSWQPQDFLPDPSSDGFYDEVKELRERAKEIPDDYFVCLVGDMVTEEALPTYQTMLNTLDGVRDETGASPTTWAVWTRAWTAEENRHGDLLNKYMYLTGRVDMKQIEKTIQYLIGSGMDPGTENNPYLGFLYTSFQERATFISHGNTARHAKEYGDLKLAQICGTIAADEKRHETAYTKIVEKLFEIDPDYTVLAFADMMRKKISMPAHLMYDGKDDNLFEHFSAVAQRLGVYTARDYADILEFLVQRWKVADLTGLSGEGRRAQDFVCTLAPRIRRLDERAQARAKQAPVIPFSWVYDRKVQL
What is the function of this protein?
Converts stearoyl-ACP to oleoyl-ACP by introduction of a cis double bond between carbons 9 and 10 of the acyl chain.
What are the official names of this protein?
Stearoyl-[acyl-carrier-protein] 9-desaturase 5, chloroplastic, Stearoyl-ACP desaturase 5, Acyl-[acyl-carrier-protein] desaturase 5.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid. Note=In green tissue, found in chloroplasts. In non-photosynthetic tissue, found in plastids.
Protein: HMUV_PSEPF
Sequence: MLRAHNLHIRRGRKTVLADVSLQLEPGEVLGVLGPNGAGKSTLLGALCGELSAHEGDVLLDGEALSRWSGTQRAQRLAVLPQVSTLDFAFRVEEVVGMGRLPYQSGRVRDDEIVAAALRAADAGHLSGRSYLALSGGERQRVHLARVLAQLWPGQAGQTLLLDEPTSMLDPLHQHTTLQAVREFADRGAAVLVILHDLNLAARYCDRILLLEGGRPVALDTPQQVLRPESLKAVFGLEVLVQTHPERGHPLIIAR
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PHYDA_ECOLC
Sequence: MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEIDATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
What is the function of this protein?
Catalyzes the stereospecific hydrolysis of the cyclic amide bond of D-hydantoin derivatives with an aromatic side chains at the 5'-position.  Has no activity on dihydropyrimidines.  The physiological function is unknown.
What are the official names of this protein?
D-phenylhydantoinase, Hydantoin-utilizing enzyme HyuA.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.