PharMolix/UniProtQA huggingface dataset:
Protein: ARGB_THENN
Sequence: MRIDTVNVLLEALPYIKEFYGKTFVIKFGGSAMKEEKAKKAFIQDIILLKYTGIKPVIVHGGGPAISQMMKELGIEPVFKNGHRVTDERTMEIVEMVLVGKINKEIVMNINLHGGRAVGICGKDSKLIVAEKETKYGDLGFVGKVKQVNPEILHALIENDYIPVIAPVGIGEDGHSYNINADTAAAEIAKSLMAEKLILLTDVDGVLKDGKLLSTLTPEEAENLIKDGVVTGGMIPKVECAISAVREGVGAVHIINGGLEHAILLEIFSRKGIGTMIKESEG
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR18_ANTAG
Sequence: MNKFKRSSRRRLPPIRSGEIIDYKNTSLLRRFISEQGKILSRRMNKLTSKQQRLVTVAIKRARILALLPFLNNES
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PYRC_BACAH
Sequence: MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: RL3_ECO8A
Sequence: MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDGYRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFADVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKKMAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NU4M_ACACA
Sequence: MAFLLYYTLFISFMLWLAALLIISFSVYGSPEKVKLIKKTSLFFSFFQFILIIFFWILSDNISVLAEFDIYNFQFYKQWLFLYNFHYVIGMDNISLLFLLLTFFLTPICILISWNSIKYRYNSFIICLIFITFILFNIFCVLDLVFFYIFFESILIPMFILIGVWGSRQRKIHAVYQLFFYTLLGSLLMLLGILVIYSHIQTTDIRVLYNTNFSFYRQLILWASFFFAFCVKVPLFPFHIWLPEAHVEAPTVGSVILAGVLLKLGTYGLLRFVIPIFCDATYFFLPLVYTLCLLGIIYTCCSTIRQVDLKKVIAYASVSHMSFVILGLFTSNIQGIGGSVFLMLSHGIVSSGLFFCIGCVYDRYKTRILRYYSGLVSTMPIFSLCLFILILSNISFPGTSSFIGEFLILLGLFENNHFAALIATFSIILTAVYSIWLYNRIIFNRLVVNYYLRFSDFSKKEFVVGFIFCFITILFGLKGSYIISLIEAPLYVYLSFK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: TANK_MOUSE
Sequence: MSLKRHSLRRNACHLETRAGIPTILYSDATGQRGMDKNIGEQLNRAYEAFRQACMDRDSAVRELQQKQTENYEQRIREQQEQLSFQQNLIDRLKSQLLLVDSSRDNSYGYVPLLEDSDRRKNNLTLDEPHDKVKLGTLRDKQSKVRRQEVSSGKESAKGLNIPLHHERDNIEKTFWDLKEEFHRICLLAKAQKDHLSKLNIPDIATDTQCSVPIQCTDKTEKQEALFKPQAKDDINRGMSCVTAVTPRGLGRDEEDTSFESLSKFNVKFPPMDNDSIFLHSTPEAPSILAPATPETVCQDRFNMEVRDNPGNFVKTEETLFEIQGIDPITSAIQNLKTTDKTNPSNLRATCLPAGDHNVFYVNTFPLQDPPDAPFPSLDSPGKAVRGPQQPFWKPFLNQDTDLVVPSDSDSELLKPLVCEFCQELFPPSITSRGDFLRHLNTHFNGET
What is the function of this protein?
Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity.  Acts as a regulator of TRAF function by maintaining them in a latent state.  Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation.  Negatively regulates NF-kappaB signaling and cell survival upon DNA damage.  Plays a role as an adapter to assemble ZC3H12A, USP10 in a deubiquitination complex which plays a negative feedback response to attenuate NF-kappaB activation through the deubiquitination of IKBKG or TRAF6 in response to interleukin-1-beta (IL1B) stimulation or upon DNA damage.  Promotes UBP10-induced deubiquitination of TRAF6 in response to DNA damage.  May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.  Essential for the efficient induction of IRF-dependent transcription following infection with Sendai virus.
What are the official names of this protein?
TRAF family member-associated NF-kappa-B activator, TRAF-interacting protein, I-TRAF.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMKL_SHEDO
Sequence: MFNFFAAAPKGFEYSLANELTEFGATDVKESVAGVYFSSSLELAYRITLWTRLASRIVVVIYKGPCESPEQLYNAAYCIDWPSHFSNKKTFSIDFHGTGGFINNTQFGALKIKDAVVDRFRDDGDARPNVERVDAEFRVDAHYRNGQLTISVNFSGPSLHQRGYRSTTGEAPLKENLAANMLVRSGWQAEQVDLLDPFCGSGTVLIEAALMACDIAPGLKRQRFGFESWRQHNATMWNKVLEEAHARASLGRTRCKVKFYGSDIDPRMVSLAKRNAENAGVDELIEFSEMDALNVKVPCETGFMISNPPYGERLGNITELLQLYYQFGDKLKQDFGGWKVAMLCSDVELISSLKLKADKQMKMFNGALECAFNLYTLHANSTRRDAPVLPEGVDDIADIAPAFANRIKKNVKTLGKWAKKEGIDSYRLYDADLPEYNVAIDKYVDYVVIQEYSAPATIPEAVTKRRLSDVLLALPNALGIHPDKITLKTRERQKGTNQYQKLAEKKLEIITQEYGAKFKLNLTGYLDTGLFLDHRVTRKLVGEKAKGRKVLNLFSYTGSASVHAALGGAKSVTTVDMSNTYISWAKENFELNGINLKNHEFVQADCLQWVDDCREQFDLIFIDPPTFSNSKRMEDSWDVQRDHVALLGKLIKLLSPKGELIFSNNKRKFKMDIEALTALGATVNNIDELCLPLDYKRNPHIHNVWLLTHGK
What is the function of this protein?
Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase K/L.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmKL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUN10_ARATH
Sequence: MEEKSKSRGWCGWFIAIIVLASVILAVVYTVKLRTKKSGDDDGGGPVPGPPGAIDKKYADALKLALQFFDIQKSGKLENNKIPWRGDSGLKDGSEDNLDLSKGLYDAGDHIKFGFPMAFTATVLSWSILEYGDQMNAVNQLDPAKDSLRWITDYLIKAHPSDNVLYIQVGDPKVDHPCWERPEDMKEKRPLTKIDVDTPGTEVAAETAAAMASASLVFKDSDPTYSATLLKHAKQLFNFADTKRGSYSVNIPEVQKFYNSTGYGDELLWAASWLYHATEDKTYLDYVSNHGKEFASFGNPTWFSWDNKLAGTQVLLSRLLFFKKDLSGSKGLGNYRNTAKAVMCGLLPKSPTSTASRTNGGLIWVSEWNSMQQSVSSAFLASLFSDYMLTSRIHKISCDGKIFKATELRDFAKSQADYMLGKNPLGTSFVVGYGDKYPQFVHHRGASIPADATTGCLDGFKWFNSTKPNPNIAYGALVGGPFFNETFTDSRENPMQNEPTTYNNALLVGLLSSLVTTSSTLQSLK
What are the official names of this protein?
Endoglucanase 10, Endo-1,4-beta glucanase 10.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: CCX2_ARATH
Sequence: MGFSFSSNRFGYLTVTFLLVISCLLLGFFTNPVDSSALRPKSEHDCSALKHFHDYKSKCAYLKSIDPCASQGFFDYLSFLYCNFEGFPILGQFLLFLWLLLLFYLLGHTASEYFCSSLESLSKLLNLSPTVAGVTLLSLGNGAPDLFASLVSFMGESKGTYDVGLNTVVGGSGFVTCVVVGIISISLHKRRVRIERAAFIRDICFFCAAIGSLALILVYGKINFWGALGFCSLYAVYVAFVVLSWRFGGDQGAESDLESIHKRGSLSEPILQRDGLEEIEDGVVNGEHQIVDDDDDHQRYYYWKRLVIWAITLPLNLPRILTIPVVSEDKWSKPLAVASVTFAPVLLSFLWNWKRKPTSFEAGVVYLIGCLIGIALGFIAGATTKKLTPPKKWLLPWLAGGFVMSMTWSYISAQELVALLTSLGYIFGVSPSILGLTVLAWGNSIGDLITNLTMALHDGNEGAQVAVSGCYAGPIFNTLFALGISLVGCAWEAYPLSIVIKTDPRLLESLGFLVAGLVWSFLVLFSNRMRLGGVMGIGLLVIYLASLSLRIMQTVGDAH
What is the function of this protein?
Membrane-localized H(+)-dependent K(+) and Na(+) transporter.
What are the official names of this protein?
Cation/calcium exchanger 2, Protein CATION EXCHANGER 8.
What is the protein family that this protein belongs to?
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/calcium exchanger (CCX) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PG096_VACCA
Sequence: MEVIADRLDDIVKQNIADEKFVDFVIHGLEHQCPAILRPLIRLFIDILLFVIVIYIFTVRLVSRNYQMLLALVALVITLTIFYYFIL
What is the function of this protein?
Early protein involved in virion morphogenesis.  Participates in the formation and elongation of crescent-shaped membrane precursors of immature virions in cytoplasmic factories.
What are the official names of this protein?
Protein OPG096, Protein L2.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG096 family.
Protein: VATD_METMA
Sequence: MAQQDVKPTRSELINLKKKIKLSESGHKLLKMKRDGLILEFFKILNEARNVRTELDAAFAKSTEKINLASAVNGMVAVRSTAFTAKESPEIQLSGHNIMGVVVPKISSTGVRKSLYERGYGIIGTNSYIDETADAYEDLVEKIITAAELETTMKRLLDEIEKTKRRVNALEFKVIPELIDTMKYIRFMLEEMERENTFRLKRVKARMRD
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: RSC4_SCHPO
Sequence: MVDDSHNAPFDKTKFDEVLEALVGLKDNEGNPFDDIFEELPSKRYFPDYYQIIQKPICYKMMRNKAKTGKYLSMGDFYDDIRLMVSNAQTYNMPGSLVYECSVLIANTANSLESKDGTLNEEENEEMESSINEEHKPGTNEIDVPKVIQNILDALHEEKDEQGRFLIDIFIDLPSKRLYPDYYEIIKSPMTIKMLEKRFKKGEYTTLESFVKDLNQMFINAKTYNAPGSFVYEDAEKLSQLSSSLISSFSEQPKEHSPATSKHEPEETPASPTPSVSASTSRERSTSVAPSFITSDQAATPDVLKSEEAHVESFSKESEKDQTPIPEDVPSPMDTLSQANYGAFALIKSFPSTPVPDFLNFSHKSVMGRSTFNMPNFPEPKFFEDIPNTERCILSAFICSPPQLPLPNPLRMYLPCPSLNSTEVSVITLAPQHSFLNIVINLNPALALKSYTIITLLNGKRLGAGVSTPPSTLYALEGIKHTEEPIRTVYEAKLSVGLNCLEFVLGSTEPVEPPSIEPGLPASAYSRTVERERFVLMAYVQP
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  Controls particularly membrane and organelle development genes.
What are the official names of this protein?
Chromatin structure-remodeling complex subunit rsc4, Bromodomain-containing protein brd1, RSC complex subunit rsc4.
What are the subcellular locations of this protein?
Nucleus.
Protein: YCXB_EUGLO
Sequence: MLLNLFKFSKKLFQENFNKVKLLNHCKSFLFLGESDNKFFTNEKSELVFSDKRDRPFSSDRINRPFSPDKKGEPIFPDKRDRPFSPDRINRPFSPDKKGEPIFP
What are the official names of this protein?
Uncharacterized 12.4 kDa protein in rps4-rps11 intergenic region, ORF104.
What are the subcellular locations of this protein?
Plastid.
Protein: YIDD_SYNSC
Sequence: MHESNTLYGGPMTKLRQAINQVLAAVLLAGIGFYRRFISPMIGPRCRFTPTCSAYGLEAIQKHGPWKGGWLTVKRLLRCHPFTPCGCDPVPD
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSMH_PELPD
Sequence: MAGFQHLSVMPEEVLRFLSPRPGGCYLDGTLGGGGHAALVAERCAPGGGTLIGMDRDLEALKAAAERLSRFGDAVRLLHGNFADIATRLDSLGVDALDGFVLDLGVSSHQLDTARRGFSFQQEGALDMRMDGDSGETAADLVNRLPEHELERIIREYGEERWAKRIASFIVRARSEAPIENTLRLVDIIKGAIPKAKWEERLHPATRTFQALRIAVNHELESLERGLKSAIDRLKPGGRGVVISFHSLEDRIVKHVFREYAAGCTCPRNLPVCVCGRQPRVRVLTGRPVTATEEELRDNPRSRSAKLRAVEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APH1_DROME
Sequence: MTLPEFFGCTFIAFGPPFALFVFTIANDPVRIIILIAAAFFWLLSLLISSLWYALIPLKEFLAFGVVFSVCFQEAFRYIIYRILRSTEQGLHAVAEDTRVTDNKHILAYVSGLGFGIISGMFALVNVLADMSGPGTMGLKGGTELFFVTSAAQALSIILLHTFWSVIFFNAFDTNNYIHIGYVVFSHLFVSLITLLNANELYTTTLLINYLVTILTGVLAFRVAGGTSRSFRKFITCQ
What is the function of this protein?
Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch.  It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex.
What are the official names of this protein?
Gamma-secretase subunit Aph-1, Presenilin-stabilization factor.
What is the protein family that this protein belongs to?
Belongs to the APH-1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: GGPP9_ARATH
Sequence: MATTVHLSSSSLFSQSRGRRDNSISSVKSLRKRTVLSLSSALTSQDAGHMIQPEGKSNDNNSAFDFKLYMIRKAESVNAALDVSVPLLKPLTIQEAVRYSLLAGGKRVRPLLCIAACELVGGDEATAMSAACAVEMIHTSSLIHDDLPCMDNADLRRGKPTNHKVYGEDMAVLAGDALLALAFEHMTVVSSGLVAPEKMIRAVVELARAIGTTGLVAGQMIDLASERLNPDKVGLEHLEFIHLHKTAALLEAAAVLGVIMGGGTEQEIEKLRKYARCIGLLFQVVDDILDVTKSTEELGKTAGKDVMAGKLTYPRLIGLEGSREVAEKLRREAEEQLLGFDPSKAAPLVALASYIACRHN
What is the function of this protein?
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.
What are the official names of this protein?
Geranylgeranyl pyrophosphate synthase 9, chloroplastic, GGPP synthase 9, GGPS9, (2E,6E)-farnesyl diphosphate synthase 9, Dimethylallyltranstransferase 9, Farnesyl diphosphate synthase 9, Farnesyltranstransferase 9, Geranyltranstransferase 9.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LCP4_DROME
Sequence: MFKILLVCALVALVAANENPEVKELVNDVQADGFVSKLVLDNGSAASATGDVHGNIDGVFEWVSPEGEHVRVSYKADENGYQPQSDLLPTPPPIPEAILKAIAYIQAHPSKE
What is the function of this protein?
Component of the larval cuticle.
What are the official names of this protein?
Larval cuticle protein 4, Larval cuticle protein IV.
Protein: LCE6A_HUMAN
Sequence: MSQQKQQSWKPPNVPKCSPPQRSNPCLAPYSTPCGAPHSEGCHSSSQRPEVQKPRRARQKLRCLSRGTTYHCKEEECEGD
What is the function of this protein?
Precursors of the cornified envelope of the stratum corneum.
What are the official names of this protein?
Late cornified envelope protein 6A.
What is the protein family that this protein belongs to?
Belongs to the LCE family.
Protein: RL6_XANOM
Sequence: MSRVAKKPVSLPKGVELNVQSELVSVKGPKGTLTLPKPTGVEIAIDGDVATLSANDPSQIAITGTVRAILANMVKGVSEGFERKLELVGVGYRAAMQGKDLSLALGFSHPLVFVAPEGITLSTPTQTEILVQGADKQRVGEVAAKIRGFRPPEPYKGKGVKYAGEVIIRKEAKKA
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CRTJ_MYXXA
Sequence: MSASTQGRRIVVVGAGVGGLAAAARLAHQGFDVQVFEKTQGPGGRCNRLQVDGFTWDLGPTIVLMPEVFEETFRAVGRRIEDYLTLLRCDPNYRVHFRDRSDVTFTSELCAMGRELERVEPGSYARYLAFLAQGRVQYRTSLDHLVGRNYAGLRDYLSPRVLARIFQVRAHRRMYADVSRFFQDERLRAAMTFQTMYLGVSPYASPAVYGLLPFTELGVGIWFPKGGLYAIPQALERLAREEGVRFHYGAPVERILTDGGRTRGVRLEGGEVVEADAVLCNADLPYAYEKLLDPKATTLKRKEKLRYTSSGYMLYLGMKRRYPELLHHNVVFGRDYKGSFDDIFEFRVPEDPSFYVNAPTRTDASLAPEGKDALYVLVPVPHQHPDLDWKVEGPKVRAKFFARMAELGFPSLESDIEVERRSSTPDDWAGTFNLARGSGFGLSQNFTQIGPFRPSNQDARVKNLFFVGASTQPGTGLPTVLISARLVTERLMTWAHAQGVSLSPRTAAATPLEGVAA
What is the function of this protein?
Dehydrogenates carotenes in the cis conformation: has cis-to-trans isomerase activity and mediates dehydrogenation of cis-phytoene, producing zeta-carotene via the intermediary of phytofluene by the symmetrical introduction of 2 double bonds at the C-11 and C-11' positions of phytoene.
What are the official names of this protein?
zeta-carotene-forming phytoene desaturase, 2-step phytoene desaturase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
Protein: NUOD_BACMK
Sequence: MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVLCHAVETMMDLEIPERAEYLRVLAMELGRVASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLSELCGARLTFNYMRVGGVKWDAPDGWIEKVKEFVPYMREQLEGYHDLVSGNEIFLNRVKGVGVYSAEEAISYSLSGANLRCTGVHWDLRKDEPYSIYDRFDFDVPVGSTGDAWDRYVCRMKEIEESLKIIEQAVEQFPKDGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MECA_LATSS
Sequence: MRMEKIDENTIRVLLENDDLEERGITGLDLLSNHKKIERFFYSILEEVDQDHVFANNDAVTFQVLPNEQGLELLISKNLSNLDLNKAQSEMVQGKDGITEYIKDQLLKRDTASSEDDEEDDEIESYLNQADNPTKQVVLGFDTFEDWIALAQQLHIESGVSNLFVYKHQYYAQLVFFLENTTETFVQDDLAVANEFGHKTNYTADFLSEYGQRVMENSALELTRYYFKD
What is the function of this protein?
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
What are the official names of this protein?
Adapter protein MecA.
What is the protein family that this protein belongs to?
Belongs to the MecA family.
Protein: FENR1_LYSSC
Sequence: MFEQEMYDVTIIGGGPAGLYSSFYCGLREMKTKLIESQPQLGGKIHVYPEKMIWDIGGVTPISGGQLIKQLVEQALTFNPSIYTDEKVLSIAKNDEGIFVITAESGNIHYSKTVIVAIGGGILNPQKIEIEGAERFEVSNLNYTIKSYEKFKNKAVIISGGGNTAVDWALELMEVASKVYLTYRKDQLSAHEAQITELTNSAIECHYNSEITKLIADDQEGMIKAIALTNHETGTITEIPIDEVVISHGYVRDKELLDNSPLAIERKNDYFIAGTINSESSIPGLYAAGDILHHDGKIHLIAAAFHDALHAVNSAKKYIQPDASDGGIVSSHNDIFKQRNRKLLQESLK
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: NEUR1_PONAB
Sequence: MTGERPSTALPDRRWGPRILGFWGGCRVWVFAAIFLLLSLAASWSKAENDFGLVQPLVTMEQLLWVSGRQIGSVDTFRIPLITATPRGTLLAFAEARKMSSSDEGAKFIALRRSMDQGSTWSPTAFIVNDGDVPDGLNLGAVVSDVETGVVFLFYSLCAHKAGCQVASTMLVWSKDDGVSWSTPRNLSLDIGTEVFAPGPGSGIQKQREPRKGRLIVCGHGTLERDGVFCLLSDDHGASWRYGSGVSGIPYGQPKQENDFNPDECQPYELPDGSVVINARNQNNYHCHCRIVLRSYDACDTLRPRDVTFDPELVDPVVAAGAVVTSSGIVFFSNPAHPEFRVNLTLRWSFSNGTSWRKETVQLWPGPSGYSSLATLEGSMDGEEQAPQLYVLYEKGRNHYTESISVAKISVYGTL
What is the function of this protein?
Catalyzes the removal of sialic acid (N-acetylneuraminic acid) moieties from glycoproteins and glycolipids.  To be active, it is strictly dependent on its presence in the multienzyme complex.  Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage (By similarity).
What are the official names of this protein?
Sialidase-1, Acetylneuraminyl hydrolase, Lysosomal sialidase, N-acetyl-alpha-neuraminidase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 33 family.
What are the subcellular locations of this protein?
Lysosome membrane; Peripheral membrane protein; Lumenal side. Lysosome lumen. Cell membrane. Cytoplasmic vesicle. Note=Localized not only on the inner side of the lysosomal membrane and in the lysosomal lumen, but also on the plasma membrane and in intracellular vesicles.
Protein: E2SN1_SYLSP
Sequence: MFTMKKSLLFLFFLGTISLSLCEQERGADEDDGGEEVKRGIFSLFKAGAKFFGKNLLKEAGKAGAEHLACKAANQC
What is the function of this protein?
Antimicrobial peptide.  Active against some Gram-negative and a variety of Gram-positive bacterial strains.  Not active against fungi.  Shows very weak hemolytic activity against human erythrocytes.
What are the official names of this protein?
Esculentin-2SN1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Esculentin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AROB_CORP2
Sequence: MQTIEVNGASPYEVTIGHNLFKDVAKSMSQLGANQAAIITQPVMGETAKKLVGAIEALGKEATIITVPDAEDGKNLNVAGDCWDVLGRKAFGRKDVIISLGGGAVTDLAGFVAACWMRGIAVIHVPTTLLSMVDAAVGGKTGINTSAGKNLVGAFHEPSGVFIDLDMIATLPDREKISGSAEIIKTGFIADTKILSLYEEDPEACFNVEGYLPELIARSVAVKARVVASDLREAGQREILNYGHTFGHAVELKEKYEWRHGNAVSVGMMFVAALARNRGLITDELYLRHKNILSSVGLPTTYPEGHFAELYQAMLRDKKNRDGRIRFVALIGAGKTIRIEDADRAELIAAYETLNKGGV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMBP_RAT
Sequence: MQGLGALFLLLTACLTLKADNVPTLPDIQVQENFNEARIYGKWFNLAVGSTCPWLRRIKNKMSVSTLVLQEGATEAEISVTSTQWRKGVCEEISGVYQKTDIDGKFLYHKSKWNATLESYVVHTNYDEYAIFLTKKFSHRHGPTITAKLYGREPQLRDSLLQEFREVALSVGIPENSIVFMADRGECVPGDREVESTSFARARRAVLPQENEGSGSEPLITGTLKKEDSCQLNYSEGPCLGMQQKYYYNGASMACETFQYGGCLGNGNNFASEKECLQTCRTIAACNLPIVQGPCRAFAELWAFDAAQGKCIQFIYGGCKGNGNKFYSEKECKEYCGVPGDGYEELTRS
What is the function of this protein?
Kunitz-type serine protease inhibitor.  Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation.  Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
What are the official names of this protein?
Protein AMBP.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
[Alpha-1-microglobulin]: Secreted. Endoplasmic reticulum. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein. Nucleus membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein. Secreted, extracellular space, extracellular matrix. Note=The cellular uptake occurs via a non-endocytotic pathway and allows for localization to various membrane structures. A specific binding to plasma membrane suggests the presence of a cell receptor, yet to be identified. Directly binds collagen fibers type I.