PharMolix/UniProtQA huggingface dataset:
Protein: RS7_TRIL1
Sequence: MPRRREVPKRVILPDPKYNDKTVAKLINILMVGGKKSVAESILYRALDIVESKSGEEAVKALKKCLDNIKPALEVKSRRVGGSTYQVPVEVRPDRRVSLAMRWLIKYSAARSEKTMTEKMAGEILDAFNSRGAAVKKREDTHKMAEANRAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: END4_CAMC1
Sequence: MRYIGAHVSAAGGVSNAPINAAKIGANAFALFTKNQRQWSAKELSEGEIEQFKANLKASGISADHVLPHASYLINLGHPEKEARAKSLEAFIDEIERASKLGLKLLNFHPGSHLKQISQNECLDNIARCINEALKRTSGVKLVIENTAAQGSNLGFDFAQLAYLIERVDDESRVGVCIDTCHAFAAGYDLRSKEAYAKTMGEFDAVIGYKFLSGMHLNDAKFGLGSKKDRHESLGKGELGLGAFENIINDDKIGEIPLILETIDESIWEDEIKILRNLEKEKL
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: NAT10_CAEEL
Sequence: MRTKLDGRIRTQIENGVASGHRSMFAVVGDKARDQVPILYHILSKSTVSARPNVLWCYKKELSFSTHRAKKAKKMKKATTTISGSLPDADPFDVFISSTQIRYCYYNETEKILGNTFGVLVLQDFEAMTPNLLARTIETIEGGGMVILLMQSVRSLRQLYTISMDVHNRYRTEAHNEITARFNERFILSLASCSSVLVLDDQLRVLPISSHIENVEAIPASQKKIQSESDAELASLKEAMKETKPIGPLLSRARTACQAKALLRFLDVITEKQSNVTCSLTAGRGRGKSAAVGLSLAGAIAFGYTNIFVTSPSPENLKTLFEFVVKGFDALDYQEHTDYELIQSANPEFKNCLVRINVFREHKQTIQYISPTDVQKLGQCELIVIDEAAAIPLPLVKELISGPYISFLSSTINGYEGTGRSLSLKLLQQLRQQSAGGEAKEGKSASNKGKTLHEMHMEESIRYKPGDKIEKWLNRLLCLDATNCQLKLECGTPPPAACELYIVNRDTLFSFHDASEAFLQQVMAIFVSAHYKNSPNDLQMLSDAPAHNLFVLMAPIDKSRKTIPEVLAVVQVCLEGRLDSDNIQNGLESGKRAAGDLLPWTVSQQFMDKQFGTLCGGRIVRVAVHPDYQSMGYGGRAVQLIEQYYLGLATSLDEEEKAPAPPSKTVIKQVKDGHTVELLEERIEPRADLPPLLQRLDERKPERLDYLGVSFGLTVPLLKFWKRNEFVPVYIRQNSNDITGEHTCIILKGLEHGGSDSDEEPSATWLPVYWREFRRRIVNLLSFDFSSFPAQMALSLLQLKNKHVEKQMKRLVIERSELAIHLSNTDLRRMSQYGRNMVDSHIITDILPIVAKLNFEQRLPQELKLAVTQSAILLARGLQHKHFEDISKELDLPMNQIFALLTKAIRRIGDWFDEVCETAVRENLDKEAEASAANKPTSSLPKAVPLANLEDELESAAKEIRARHDRDRKALLAELGNELQKYEIIQDEKELAEAYESVNMKYANKLVSVKSKRTAIQAAIPDAKDPANKNAKKKKRFSSGGRR
What is the function of this protein?
RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs.  Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA.  Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis.  Catalyzes the formation of ac4C in serine and leucine tRNAs.  Requires a tRNA-binding adapter protein for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
RNA cytidine acetyltransferase, 18S rRNA cytosine acetyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CEP44_BOVIN
Sequence: MATGDLKRSLRNLEQVLRSLNYPREVDCVGLVKGDTAASLPIISYSLTSYSPYVAELLVDSNIELLAKNDLRFIDTVYKLLRDQFNYKPILTKKQFIQCGFAEWKIQIICDILNCVMKKHKELSSLEKTPSQQRKKTSSAKSEPCSSTEKTSTEPVGIDVTGRFVTSGKKKAVVIRHLYNEDGANIPEDTVTDVNEAFDVCDIKAAEITIPELQVPDINCEQEDITVNPEVTALQSMLAECQEKLKKLTCIESRLESLEEKMKGKVLVNEKTWANLLSRVTLLETEMLLSKKNDEYMQFNEMSEDYSSSSDMDSLNPDRKSKEERHANIPLSSGYSTVSSDSTPRTSTVNYCGLKEISEETTMQKMERMKKMFEETAELLKCPNH
What is the function of this protein?
Centriole-enriched microtubule-binding protein involved in centriole biogenesis.  In collaboration with CEP295 and POC1B, is required for the centriole-to-centrosome conversion by ensuring the formation of bona fide centriole wall.  Functions as a linker component that maintains centrosome cohesion.  Associates with CROCC and regulates its stability and localization to the centrosome.
What are the official names of this protein?
Centrosomal protein of 44 kDa, Cep44.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Midbody. Note=Localizes to the proximal end of mother and daughter centrioles.
Protein: INUE_PICGM
Sequence: MRAFLALIFLTFVMNVESSRPLMAFTPSHGWMNDPNGQFYDSKNELWHLYYQYNPNDTVWGTPLYWGHATSKDLSTWKDYGATIGPDRDEDGIFSGNIVVDHNNTSGFFNDSIDPRQRVVAIYTYNTEGSQTQHVAYSLDGGYTFEKYEHNPVLDVDNINFRDPKVFWHEPTNQWIMVIALSQQFKIQIYGSIDLTNWSLHSNFTGGLFGFQYECPGLIEVPAEGTDESKWVMFIAINPGSPLGGSSNQYFIGSFDGFEFVPDDSQARLMDYGKDFYAFQTFDNAPKESGVVGLAWASNWQYANLAPTKEWRSSMTLARQMTLASRNMNPETKVLSLLQKPIFGESVVAANKISKRNITGQDEQAVKIHKNSTGTFSFDITFSVDSSKNQTGQLQVISGQNGESIRAGFDPTAGQFFVDRGNTSGLKENPFLTDKTSAYVEPWKHQNDLPVYKMFGVIDGNLIEVFLNDGIATLTNTFFIPGTEGLEYLEIESSSDAIHIVESEVKELKLRATS
What is the function of this protein?
Exo-inulinase involved in utilization of the plant storage polymer inulin, consisting of fructooligosaccharides with a degree of polymerization (DP) value from 2 to 60.  Splits off terminal fructose units successively from the non-reducing end of the inulin molecule.
What are the official names of this protein?
Extracellular exo-inulinase inuE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPH_PECAS
Sequence: MAELTAIRGLAFDLDGTLIHSAPGLAAAIDQALVAQSLPAAGESRVATWIGNGADVMVERALRWAGVEPTAARVQETRERFDSYYAQTVDSGSTLFLQVKETLAQLAQQGVPMAVVTNKPTPFVAPLLAGLGIGDYFSLIIGGDDVIVKKPHPAPLYLVLGKLGLRASELLFVGDSRNDIQAAQAAGCRSVGMTYGYNYGEAIELSQPDVVLDRFADILPLIGHSSSHNQEPLV
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: KEFC_ECOSM
Sequence: MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAIPLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefC, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HV64D_HUMAN
Sequence: MEFWLSWVLLVAILKDVQCEVQLVESGGGLVQPGGSLRLSCSASGFTFSSYAMHWVRQAPGKGLEYVSAISSNGGSTYYADSVKGRFTISRDNSKNTLYLQMSSLRAEDTAVYYCVK
What is the function of this protein?
V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition (PubMed:24600447).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Immunoglobulin heavy variable 3-64D.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: CBIT_SULIK
Sequence: MEWKYVIPGIPDNFFERDEEIPMTKEEIRALALSKLRIRKGDMILDIGCGTGSVTVEASLLVGSTGKVYGVDKEEKAINLTRRNAEKFGVLNNIVLIKGEAPEILFTINEKFDRIFIGGGSEKIKEIISASWEIIKKGGRVVIDAILLETVNNAISAMENIGFMNLEITEVIIAKGMKTKVGTAMMTRNPIFIISGEKQ
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
Protein: EX7S_SODGM
Sequence: MPKKAEKPASFETALKELEQIVTRLESGELPLEQALNEFEQGVQLARQGQKTLQQAEQRVQILLNDTPDAPLAPFAPENDAL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPIS_CLOAB
Sequence: MRTPIIAGNWKMNNTISESLKLIEELKPLVKDAKAEVVVAPTAVSLETVVNATKGSNIKVAAQNAHFEESGAFTGEISLKALEELGVSYVILGHSERRQYFNETDCALNKKVKAAFAHNITPILCCGETLEEREANVTNEVTGKQIKLDLAGLSAEQAAKVVIAYEPIWAIGTGKTATDEQANETIGAIRKTVEVMFGKEVAEKVRIQYGGSVKPNTIKAQMAKPEIDGALVGGASLKAADFAAIVNF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSRP_RALSO
Sequence: MTDLAAKPGIRTVFIVSDGTGITAETFSHSILAQFEMKFRQVRIPFVDTVDKAHVAVSKINEAFHVEGMKPIVFTTLVDAEANRIVHQARATILDMFQTFIEPLERELGLKSSHAIGRFHQNADTEAYKNRIEAINFSLAHDDGQSHKNLAEADVILVGVSRSGKTPTSLYLAMQYGVKSANYPLIPDDFERGKLPTVLYEYKSKIFGLTIDPQRLSEIRNERRPGSKYAALENCRYEVNEAETLMRRESIKWLSSTHKSIEEIATTILQDIKMERDAY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: PTH_SALCH
Sequence: MAIKLIVGLANPGTEYAATRHNAGAWYVDLLAERLRAPLREEPKFFGYTSRITLEGEDVRLLVPTTFMNLSGKAVGAMVSFYRIQPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRVGIGHPGDKNKVVGFVLGKPPVSEQKLIDEAIDEAARCTELWFKEGLAKATSRLHTFKAQ
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPAT_TRIL1
Sequence: MAKINDNYLKLKAGYLFPEIGRRVREFTAANPSAKVIRLGIGDVTRPLAPTVLKAFHAAVDDLATTDQFAGYGPEQGYDWLINAIIEKSYKPLGVDLKTEEMFISDGSKCDCANILDIFALDNVVAIGDPVYPVYNDTNVMIGRTGEADEKGYYQNIVYLPCNEANNFIPSLPTQKVDIIYLCFPNNPTGTVASKAELKKWIDYANANDAIIFFDAAYEAFITNPEIPHSIYEIEGAKKCAIEFRSFSKTAGFTGVRCGLVVVPEEVMGTTASGEKYSFNKLWLRRTTTKFNGASYPVQRAAAAVYSEEGWKQTKEIIDYYMENARIIREGLKEVGVTCYGGVDAPYIWLKTPGGMSSWDFFDKLLNECNVVGTPGSGFGPSGEGFFRLSAFGHRENVIEAVERIKKNLK
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: RL28_ECO24
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ORF45_NPVAC
Sequence: MLPYEMVIAVLVYLSPAQILNLNLPFAYQKSVLFASNSAKVNERIRRRARDDNDDDPYFYYKQFIKINFLTKKIINVYNKTEKCIRATFDGRYVVTRDVLMCFVNKSYMKQLLREVDTRITLQQLVKMYSPEFGFYVNSKIMFVLTESVLASICLKHSFGKCEWLDKNIKTVCLQLRKICINNKQHSTCLSY
What is the function of this protein?
Plays a role in the expression of ORF41, which itself is required for late gene expression.
What are the official names of this protein?
Protein ORF45.
Protein: PYRF_VIBPA
Sequence: MIDQKVIVALDYDNQADALAFVDRIDPASCRLKVGKEMFTLFGPDFVRELHKRGFSVFLDLKFHDIPNTCSKAVRAAAELGVWMVNVHASGGERMMTASREILEPYGKDRPLLIGVTVLTSMEQSDLAGIGLNVEPQEQVIRLATLTKNSGLDGVVCSAQESSLLKNELGKEFKLITPGIRPAGSDQGDQRRIMTPVDAIQAGSDYLVIGRPITQATDPAAVLKSINDSLASK
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CLPP_PELPD
Sequence: MYIPMVVEQSGRGERAYDIYSRLLKERIIFLGGGIDDQVANLIIAQLLFLEAEDPDKDIHLYINSPGGVVTSGMAIYDTMRYIKAPVSTICVGQAASMGAVLLAAGEKGKRFSLNHSRIMIHQPLGGFQGQATDISIHAKEILRMKEELNSILADLTGQSKERIEADTDRDYFMSATEAEEYGLIDATFTRKPDSGGTP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GREA_ALKCK
Sequence: MAEEKKHYMTAEGKKKLEEELHYLITTRRKEVVERIKVARSFGDLSENSEYDSAKEDQAFVEGRIAQLEKMIRNAVMIENEKVDGNVVSLGKTVRLMELPDGEEEEYTIVGSAESDPFEGKISNDSPMAQSLLGKTVNDRVVVNTPGGEMEVEILEIR
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: RPOZ_SHIFL
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQELEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: AROA_BACC3
Sequence: MKERTIQPVNNGLNGNITIPGDKSISHRAVMFGAIAEGKTTIKGFLPGADCLSTISCFKEMGVDIVQNGDEVTVVGKGLEGLQEPKAILDVGNSGTTIRLMSGILANTPFFSCVQGDASIAKRPMKRVTNPLKQMGANIDGREEGTFTPLTIRGGDLKAIEYTSPVASAQVKSAILLAGLRAEGVTAVTEPHISRDHTERMLEAFGVKVTREGKTVKLAGGQKLTATDVQVPGDVSSAAFFLVAGAIIPNSKLVLQNVGMNPTRTGIIDVLEKMGATFTVEPINEGASEPAANITIETTSLKGIEIGGDIIPRLIDEIPVIALAATQAEGITVIKDAHELKVKETNRIDTVVAELTKLGARIEATDDGMIIYGKSALKGNTVNSYGDHRIGMMLAIAGCLAEGKTTIEDAEAVGVSYPTFFEELQRLTK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FMT_HALHL
Sequence: MAARIVFAGTPDFAVPGLDALVEAGVRPVAVFTQPDRPAGRGRRLTPPPVKRAAERHGLGVHQPERLGAEEAEQIRALAPDLMVVVAYGQILRRNVLDVPRFGCVNVHASLLPRWRGAAPIQRALLAGDEQTGVTLMQMDEGLDTGPMLARKATPISADETAGSLHDRLARIGADLLVAHLPEILAGAITPEPQPDDGVTYAAKLTNDESWLDPTEPAEQLERRVRALAPVPGARLQLGETPVRVLAARACAGRPEDRAGTVAAVGSGGIEVATGEGRLEITRLKPAGGREQTAADYLNGRRLVPGEPVQ
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: CF20D_MOUSE
Sequence: MFKNEYQGGAFVEIFSAQGKNPGAKWKILGSPSVIWKEFDKEVKSFVFVLEGSSQTNRIQLPKENKQILGLIQRFLVLQIYIPLGQDFSTELLITDLGNIKRRLYLSTVHKEVSSTPLHAKIPLFMIQRKIWCNLCIDLVAFTSEIFKGAVFQSLDGIIVSANCKLRKIFTLKSKPQETADKDDEPTDIIPRSCQLATDVPHVTQLLNMTKLRQTEIKFGGHPLRSAESEQFISSGAGSVQNSKGQDVCHIAFGSRVLGPPPLSGRRNNLRQSTETVRSIRYKNSQLCQQPTEERSVNSTEVSALLADQQGEKGSARPLKQTTPLPAKLPIPYPHPPQEPSADKGSNRRRLRLKSSSGDRTEAHCGCSSGNNRSEEDVVMALNSIPQLRTEPVRASTPEPPAPEQPDEWIFPESGGLTSDPAWSSPPLLLDEDSHTASNLWLETSKDSEHDQAEETQRAPKDIFTFSSRPRSAPHGKSHDMSPKGCPFTLDTQDDSQVTKEDPKLEGGFYGSESSEEEYNWRNYQPSQMSESELQMLASLRRQQNEDLEDTGAPHGLSASQVDHCNVSISTSSDDTTTWNSCLPPPVNQGRHYQKEMNPPSPSNPRDWLNMLSPPIVPPSQQPVEQSLDSSASLSVQGEEDPRVEEDEEVLTLLYDPCLNCYFDPQTGKYYELV
What are the official names of this protein?
Protein CFAP20DC.
Protein: SYUA_ERYPA
Sequence: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILQDMPVDPDNEAYEMPSEEGYQDYEPEA
What is the function of this protein?
Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release (By similarity).  Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores (By similarity).  Mechanistically, acts by increasing local Ca(2+) release from microdomains which is essential for the enhancement of ATP-induced exocytosis (By similarity).  Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5 (By similarity).  This chaperone activity is important to sustain normal SNARE-complex assembly during aging (By similarity).  Also plays a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity (By similarity).
What are the official names of this protein?
Alpha-synuclein.
What is the protein family that this protein belongs to?
Belongs to the synuclein family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane. Nucleus. Synapse. Secreted. Cell projection, axon. Note=Membrane-bound in dopaminergic neurons (By similarity). Expressed and colocalized with SEPTIN4 in dopaminergic axon terminals, especially at the varicosities (By similarity).
Protein: PLSY_THEPX
Sequence: MYAVLTAIIAYLIGCINNAYIFTKYTRNIDIRNYGSGNAGATNVLRVLGYKAAAPVFALDVLKGVIAVLIGKYLMGNTGAMIAGIAVVCGHNWPVFLKFRGGKGIATSVGVVMTVSPLLGLIALAIGVTVIVLTKYVSLGSITGSVTFVLLNAIFWNSTQIFIFSLILASLAIFQHRSNIKRLLAGTESKLGQKTEIK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNN14_CANAL
Sequence: MGLLSIPYQSKSKLWIAIFLVVWSLISMHFIWQSQANSGLILKNELSSTSSIPHEFEMLIDTNYPKFKPTSGHSGSQTYSNLFKNQDRNAAIFTILKNFDLEQRCQLYFKNVKNDKLIVDPDHDFKFDRFDYLNWDEYRDESIKRLKGDNDEFVATSSDLDTIKKNFDKAKSRIASDLQLLHDYFSHIKIYNQCYIDRNTSFIKKQHELIDGLNWKTSFKRSSFLSGKQIVTEQQMYPWLSQKSPEYNCLATGQTTKFAANKNSFLNTLKNNLNGKGIVMTIADAHIDYCIRLIHLLRYLKNTLPIQIIYTSNDLSAESKSQLHQASVSDFDGLPQQNITLVNVTPAIKPQYLHKFNEFGNKILAILFNTFEEMIFIDADAILIENPEKFFQLTKYKNSGALFFRDRNTSEYRPDHDIEMFLKLMNSQYDEIIFGLLQITEKTMSIPLFDRKISHVMESGLVLLNRKVHFSQPLIMANMNFFEPIRERVYGDKEMFWLSLSIIGDENYQFNSHPAAAIGQLTTYQERVKTFENPPSSFKSQEICANHPAHISDEDNHTLLWFNSGFQFCNQLEKVNYEDEFSHKERYSQFDTIDKFKTFWQSSLVIESAIIPPENTNSNGGDGYEPSVSWKHMEPYCAGYTWCAYSSIGNGDQANDRGLVINYSPEEIEHFKKLGEIWMRGYNYL
What is the function of this protein?
Responsible for addition of the terminal mannose residues to the outer chain of core N-linked polysaccharides and to O-linked mannotriose.  Implicated in late Golgi modifications (By similarity).  Involved in virulence.
What are the official names of this protein?
Putative alpha-1,3-mannosyltransferase MNN14.
What is the protein family that this protein belongs to?
Belongs to the MNN1/MNT family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.