PharMolix/UniProtQA huggingface dataset:
Protein: RCSF_ECOL6
Sequence: MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAPRATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKANAVLLHSCEVTSGTPGCYRQAVCIGSALNITAK
What is the function of this protein?
Essential component of the Rcs signaling system, which controls transcription of numerous genes.  Plays a role in signal transduction from the cell surface to the histidine kinase RcsC.  May detect outer membrane defects.
What are the official names of this protein?
Outer membrane lipoprotein RcsF.
What is the protein family that this protein belongs to?
Belongs to the RcsF family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side.
Protein: LEU1_PAEAT
Sequence: MRNAQKPSGMPIHRYLPFQDQITVEVPDRTWPDKVITKAPRWCAVDLRDGNQALIDPMSPARKLKMFQLLVKMGYKEIEVGFPSASQTDFDFVRQLIEGGHIPDDVSIQVLTQAREHLIERTYESLVGAKQAIVHLYNSTSVLQRRVVFNQDEDGILDIALQGARLCKKYEETLTDTHITYEYSPESFTGTELEYAARVCNAIADVFEASADKQVIINLPATVEMATPNVYADSIEWMHRNLHPREGIIISLHPHNDRGTGVAAAELGYLAGADRIEGCLFGNGERTGNVDLVTLGLNMFVQGVDPMIDFSDIDEIRRTVEYCNQLPVPERSPYGGDLVFTAFSGSHQDAIKKGFEALEKDAAAAGKSVDDFTWQVPYLPIDPKDLGRSYEAVIRVNSQSGKGGVAYLLKNEHNLDLPRRAQIEFSGVIQRRTDAVGGEVSGAQLWQIFQDEYLPSDEEQAQWGRYGLGSVSTETDESGAMTMNANLRIDGVEVRRTGHGNGPIAALLDILHHDGVDVRVLDYSEHALSEGGSASAAAYVECAVGERVLWGVGIDPSTTTSSLKALISAVNRAVRDAQA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
Protein: T120B_BOVIN
Sequence: MSGQLERCEREWHELEGEFQELQETHRIYKQKLEELNALQTSCSSSINKQKTRLKDLKLTLQRYKRHASREEAELVQQMGANIKERQNVFFDMEAYLPKKNGLYLNLVLGNVNVTLLSNQAKFAYKDEYEKFKLYLTIILLLGAVACRFFLHYRVTDEVFNFLLVWYYCTLTIRESILISNGSRIKGWWVSHHYVSTFLSGVMLTWPNGLIYQKFRNQFLAFSIFQSCVQFLQYYYQRGCLYRLRALGERNHLDLTVEGFQSWMWRGLTFLLPFLFCGHFWQLYNAVTLFELSSHEECREWQVFVLALTFLVLFLGNFLTTLKVVHTKLQQNRSKAKKP
What is the function of this protein?
Necessary for efficient adipogenesis.  Does not show ion channel activity.
What are the official names of this protein?
Transmembrane protein 120B.
What is the protein family that this protein belongs to?
Belongs to the TMEM120 family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: OPSD_SARMI
Sequence: TEGPYFYIPMVNTTGIVRSPYEYPQYYLVNPAAYAMLGAYMFFLIIVGFPVNFMTLYVTLEHKKLRTPLNYILLNLAVADLFMVIGGFTTTIYTSMHGYFVLGRLGCNIEGFFATLGGMISLWSLAVLAIERWVVVCKPISNFRFGENHAIMGVSLTWAMALACTVPPLVGWSRYIPEGMQCSCGIDYYTRAEGFNNESFVLYMFFCHFTIPLTIIFFCYGRLLCAVKEAAAAQQESETTQRAEREVTRMVIIMVIGFLICWLPYASVAWFIFTHQGSEFGPLFMTIPAFFAKSSSIYNPMIYICMNKQFRHCMITTLFCGKNPFEGEEEGASSTKTEASSASSVSPA
What is the function of this protein?
Photoreceptor required for image-forming vision at low light intensity.  While most salt water fish species use retinal as chromophore, most freshwater fish use 3-dehydroretinal, or a mixture of retinal and 3-dehydroretinal (By similarity).  Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins.  Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity).
What are the official names of this protein?
Rhodopsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Note=Synthesized in the inner segment (IS) of rod photoreceptor cells before vectorial transport to disk membranes in the rod outer segment (OS) photosensory cilia.
Protein: PURL_STAS1
Sequence: MSKFIEPSSEDIKIEQLYKDMGLSDEEYAKVCDILGREPNFTEIGIFSVMWSEHCSYKHSKPFLTQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNHPSAVEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELTEKQNRRLLRGVVAGIGGYGNCIGIPTTAGEIEFDDRYDGNPLVNAMCVGIIDHDMVQKGTAKGVGNSVIYVGLKTGRDGIHGATFASEELSEDSESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGAAGLTSSSSEMAAKGGSGLHLRLEQVPTREQGISPYEMMLSETQERMLLVVEKGTEQKFLDLFDKHELDSAVIGEVTDTDRFVLTYEDEVFADIPVQPLSDEAPVYVLEGTSPEYNETKNDYSSVDVESVFDQLLQHPTIASKRYLYEQYDQQVGANTIVKPGLQASVVRVEGTDKAIASTIDGEARYVFNNPYEGGKIVVAEAYRNLISVGATPLAMTDCLNYGSPEKKEIYQQLADSTKGMAEACEVLSTPVVSGNVSLYNETRETSIFPTPVVGMVGLIDDISYLNHFNPSVGDTLYVVGDTNDDFGGSQIEKLLYGQVNHEFESIDLSQEVRKGESIKQAIREGVASHVQTVGKGGLLLTLARISAHYQLGLQAKLSVTNAQLFSETQGRYIVIVKNGQSLNCDYAVEIGKVTNDQQFKVTNEQSEIVRDVKHLNDLWEGAIPQCMTATD
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurL, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit II, FGAR amidotransferase II, FGAR-AT II, Glutamine amidotransferase PurL, Phosphoribosylformylglycinamidine synthase subunit II.
What is the protein family that this protein belongs to?
Belongs to the FGAMS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFT27_BOVIN
Sequence: MVKLAAKCILAGDPTVGKTALAQLFRSDGAHFQKNYTLTTGVDLVVKTVPVPDTGDSVELFIFDSAGKELFSEMLDKLWESPNVLCLVYDVTNEQSFTNCSKWLEKARSQIPGTTLPGVLVGNKTDLAGRRVVDVAQAQAWALGQGLECFETSVKEMENYEAPFHYLAKQFHHLYREKLEVFQALV
What is the function of this protein?
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6.  Not involved in entry of the BBSome complex into cilium.  Prevents aggregation of GTP-free ARL6.  Required for hedgehog signaling.  Forms a subcomplex within the IFT complex B with IFT25.  Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis.  Essential for male fertility, spermiogenesis and sperm flagella formation.  Plays a role in the early development of the kidney.  May be involved in the regulation of ureteric bud initiation.
What are the official names of this protein?
Intraflagellar transport protein 27 homolog, IFT27, Putative GTP-binding protein RAY-like, Rab-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm. Cell projection, cilium, flagellum. Note=Localizes to the sperm flagellum.
Protein: Y1153_METJA
Sequence: MKENILKQKWAKIMKKHKYKKPKWLIKAEQKAEKMTLEEEKEWIEKAIRVYKDKGIDGLFEI
What are the official names of this protein?
Uncharacterized protein MJ1153.
Protein: TRPA_NITWN
Sequence: MTTRIDTRFAELRKQGRSAFVTFLMAGDPDPATSLAIIKALPRAGADIIEIGMPFTDPMADGPAVQAAGRRALDAGMTLTGTLRMIGEFRKDDDSTPVVLMGYYNPVYIYGVEKFLDDARAAGVDGLIVVDLPPEEDSELCIPAMKAGLNFIRLATPTTDDKRLPAVLANTSGFVYYVSITGITGSAAADSTAVGAAVGRIKRHTSLPVCVGFGIRTPDAARGIAERSDGAVVGSALVDALSASLDAEGKATSGTVQAVASLAAALAEGVRSARQAAE
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ACCD_CHLP8
Sequence: MVWFKRGIPSIKTTDKRDTPEGLWSKCDECGAALHKKQLEDHLYTCPECGHHFRISPDLYFSFLFDDGAWDEFDGQLRAADPLTFVDTKKYPDRVRDTMQKSGKSEACRNATGSMGGSAAVISAMDFGFIGGSMGSVVGEKISRAADKSVELNAPLILISQSGGARMMEGAFSLMQMAKTSARLTRLGERNIPFISLMTDPTMGGISASYAMLGDLNISEPKALIGFAGPRVIRDTIKRDLPEGFQRAEFLKEHGFVDMIVHRKDLRLQLIKLFKHLRG
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1326_ACISJ
Sequence: MRTFALFIATALAEIVGCYLPYLWLKQGRSAWLLVPAAASLALFAWLLTLHETAAGRVYAAYGGVYIGVALLWLWIVDGIRPTAWDVAGVAVALTGMGLIMFQPR
What are the official names of this protein?
UPF0060 membrane protein Ajs_1326.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MSHA_MYCA9
Sequence: MLSGDEFARRAVAALKPRRIAVLSVHTSPLAQPGTGDAGGMNVYVLQTALQLARRGVAVDIFTRATSSSDEPVVSVTDGVTVRNIVAGPFEGLDKYDLPTQLCAFTAGVLRAEAVHEPGYYNLVHSHYWLSGQAGWLARDRWGVPLVHTAHTLAAVKNQTLAEGDRPEPALRGVGEQQVVDEADRLIVNTKDEADQLVSIHNADPARIDIVHPGVDLDVFTPGDKAAARAEFGLRADEQVVAFVGRIQPLKAPDLLVRAAERLPGVRVLIVGGPSGSGLDEPTALQDLAVDLGIADRVTFLPPQTRERLAQVYRAADIVAVPSYSESFGLVAIEAQACGTPVVAAAVGGLPVAVADQRTGLLVPTHRTEDWADAIGELLVRKGAGFSRAAVEHAAGFSWSSTADSLLSSYGRAIADYRAPQRPSTQWASRARFRPRRLSGLRR
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: DJC16_CHICK
Sequence: MELGRAGPAGLLLLLLLLLAAQAAPERDPYRVLGVGRSSSQADIKKAYKRLARQWHPDKNKDPGAEDKFIQISKAYEILSNEEKRANFDRYGDAGESQGYSQHQQRQFHHFHEGFYFDESFFHFPFNSERRDTSDEKYLLHFSHYINEIVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVAQELEALGVGIGVVHAGYERRLAHHLGAHSTPSILGLINGKITFFHSAVVRENLRQFVENLLPGNLVEKITDKNYIRFLSNWKKENKPHVLLFDHMPVVPLLYKLTAFAYRDYLSFGYVYVGLRGTEELSSQYNINVYTPTLMIFKEHIDKPADVAQARDMKKQLIDDFLSQNKFLMAARLTNQRLFQELCPVKKSHRQRKHCVVLLTGEGDKFADAYEAFLTFAVANTKDTLRFAHIYNDRQPEFADALLMDEEKYRGKSAVVILERRNNAGKIAYKTLEEAWQGSNEDNFILLDLLDQLRTDPGLLSSETVLADLNDELAPMFLIRWFYSTLDYILDCWDSLFHSNWREMMPLLSLLFSALFILFGTVIVQAFSDSSDTRDSPASEKKDTTAKTEKNDTSFNKESNSRVPKKGFVEVTELTDINYNSNLVRLRPGHMNVVLILSNSTKTALLQKFALEVYTFTGSSSLHFSFLSLDKHREWLEYLLEFAQDAAPIPNQYDKHFLERDYTGYVLALNGHKKYFCLFKPHRSGDEGGTLGACEDYDSSLHTEARGKSSCSPGSRSLKNKLHKLSFWMERLLEGSLQRFYIPSWPALD
What is the function of this protein?
Plays an important role in regulating the size of autophagosomes during the formation process.
What are the official names of this protein?
DnaJ homolog subfamily C member 16, Endoplasmic reticulum DNA J domain-containing protein 8, ER-resident protein ERdj8, ERdj8.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: RL18_SERP5
Sequence: MDKKSARIRRATRARRKIKELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTLEKAVTEQLKYSGNKDAAAAVGKALAERALEKGISKVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: EF1A_METPE
Sequence: MANDKPHMNLAVIGHIDHGKSTTVGRLMFETGAVPAHIIENFRKEAESKGKGSFEFAWVMDNLKEERERGITIDIAHKRFDTAKFYFTVVDCPGHRDFVKNMITGASQADAAILVVAAPDGVMEQTKEHVFLARTLGITQLVIAINKMDAVNYDQKRFEEVKKELTQLIGMVGYKAAEILFIPMSSFKGVNISKKSPETPWYTGPTLLEALDTFKEPDKPTDKPFRLPIQDVYSISGIGTVPVGRIETGIMKKGMKVSFMPANKDGEIKSIEMHHEEQPQALPGDNVGFNVRGVGKNDIRRGDVCGPADIPPTVADEFTAQIVVLQHPSAITVGYTPVFHCHTAQIACTFVELRKKLDPRSGQTKEENPTFLKSGDAAIVQIKPSRPMVIESVKEIPQLGRFAIRDMGTTIAAGMCIAVQPKQMIR
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_RHOCS
Sequence: MAFKTLDDLSVAGKTVLVRGDLNVPVQDGRVSDTTRLDRLAPTLKELAGKGAKVVVLSHFGRPKGGPDAKNSLRQVVPALEAALGLPVAFAEDCVGESARAAIAAIEPGQVVLLENTRFHAGEEKNDPELARQMAALGDIYVNDAFSAAHRAHASTEGIAHLLPSAAGRLMQAELEALGKALARPERPVMAVVGGAKISTKLDLLLNMVTKVDMLVLGGGMANTFLFAQGRPVGKSLAEKDMADQARAIMEKAAASGCEILLPQDGAMAKEFKAGAPHRVVPVEQIADDEMMLDVGPATVEFVGLKLQGAKTVVWNGPMGAFEIRPFDSGTNAVAGLVAALTGDGRVLSVAGGGDTVAALEQAGVAGRFSYVSTAGGAFLEWLEGKELPGVKALGA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UXUA_BRAHW
Sequence: MIMTLRWFGKNFDSVTLKQIRQIPGVKGVITTLYDSKVGDAWKEEDVKNIKKEVEDAGLKIYGIESVNILDDIKIGLPSRDKYIENYIKTLEVLGKEGINLVCYNFMPVFDWTRSDLAKVRPDGSTVLSYDQDIIDKIDPQKMFEQIDSNSNGFVLPGWEPERLSRLKELFEMYKGIDDEKLFENLKYFLTAIMPTCEKYNIKMAIHPDDPAWPVFGLPRIIVNKENILRMVNSVNSPCNGITLCAGSLGSNPKNDIPDIIRSLKGKIFFAHVRNLEHTAPGKFQEAAHLSSDGSMDMFAIMKAFYDIGFEGPFRPDHGRAIWDEVSMPGYGLYDRALGAVYLQGLWEAIEKMGK
What is the function of this protein?
Catalyzes the dehydration of D-mannonate.
What are the official names of this protein?
Mannonate dehydratase, D-mannonate hydro-lyase.
What is the protein family that this protein belongs to?
Belongs to the mannonate dehydratase family.
Protein: DMBX1_MOUSE
Sequence: MQHYGVNGYSLHAMNSLSAMYNLHQQAAQQAQHAPDYRPSVHALTLAERLAGCTFQDIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPEARVQVWFKNRRAKFRKKQRSLQKEQLQKQKEAEGSHGEGKVEAPASDTQLETEQPPGLPSGDPPAELQLSLSEQSASESAPEDQLDREEDSRAEEPKAEKSPGSESKVPGCKRGSPKADSPGSLAITPAAPGGGLLGPSHSYSSSPLSLFRLQEQFRQHMAATNNLMHYSSFEVGGPAPAAAAAAAAAVPYLGVNMAPLSSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPTGLAPASAALNSKTTSIENLRLRAKQHAASLGLDTLPN
What is the function of this protein?
Functions as a transcriptional repressor.  May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence.  Required for brain development, neonatal survival, postnatal growth, and nursing ability.
What are the official names of this protein?
Diencephalon/mesencephalon homeobox protein 1, Diencephalon/mesencephalon-expressed brain homeobox gene 1 protein, Orthodenticle homolog 3, Paired-like homeobox protein DMBX1, Paired-type homeobox Atx.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA_AERS4
Sequence: MISTLLTKIIGSRNDRTLKALRKIVKQINAMEPQFEALSDSELQAKTAEYRQRLEQGETLDQLLPEAFATVREASKRVFGMRHFDVQLIGSMVLDSNRIAEMKTGEGKTLTATLPAYLNALSGRGVHVVTVNDYLAKRDAEANRPLFTFLGMTVDCNVPGMDASQKRDAYAADITYGTNNEFGFDYLRDNMAFSPEQRVQRPLNYALVDEVDSVLIDEARTPLIISGPAEDSSALYIQVNKLIPQLIKQDKEDTEEYTGEGHYTVDEKNRQALLTENGQIFVEELLKREDLLAEEDSLFSATNISLLHHVNAGLRAHTLFERNVDYIVQKDEIVIVDEHTGRTMPGRRWSDGLHQAVEAKEGVKIQNENQTLASITFQNYFRLYDKLAGMTGTADTEAFEFQQIYGLDTVVIPTNKPMVRKDMGDLVYLTAQEKYAAIVEDIRGCVSRGQPVLVGTVSIENSELLSGILTKENIPHKVLNAKFHAMEAEIVAQAGQLGAVTIATNMAGRGTDIVLGGNWQAEIAQLDNPTDEQIAELKAAWQVRHDEVLAAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSMEDTLMRIFASDRVTGMMKKLGMEEGEAIEHPWVTKAIENAQRKVEGRNFDIRKSLLEFDDVANDQRKVVYEQRNELLDTNDISETIHVIRDDVYGAVIDEYIPPQSLEEMWDVPGLEARLKADFGLDLPLQQWLAEDDKLYEEKLRERILDEATKLYAHKQELVGVEVLRNFEKAVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFDLFTQMLETLKRDVVSILSRVQVQERDVEALEEQQRQQSEAAPRTYTHATAESQLADEEAAGEEGHTTFVRDEQKIGRNDPCPCGSGKKYKHCHGQLT
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: BNZD_PSEPU
Sequence: MATHVAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPYDRPSLSKAVLDGSLERPPILAEADWYGEARIDMLTGPEVTALDVQTRTISLDDGTTLSADAIVIATGSRARTMALPGSQLPGVVTLRTYGDVQVLRDSWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRRIGAWLRGLLTELGVQVELGTGVVGFSGEGQLEQVMASDGRSFVADSALICVGAEPADQLARQAGLACDRGVIVDHCGATLAKGYSPSEMWPVGAAAGGRRSLETYMNAQRQAAAVAAAILGKNVSAPQLPVSWTEIAGHRMQMAGDIEGPGDFVSRGMPGSGAALLFRLQERRIQAVVAVDAPRDFALATRLVEARAAIEPARLADLSNSMRDFVRANEGDLT
What is the function of this protein?
Part of the electron transfer component of benzene 1,2-dioxygenase, transfers electrons from ferredoxin (BnzC) to NADH.
What are the official names of this protein?
Benzene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component, P4 subunit.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: MSCL_ACIAD
Sequence: MSIIQEFREFAVKGNMIDLAVGVIIGGAFGKIVDSLVKDIIMPLITVITGGGVDFTQKFVVLGNNPDNLQSLDALQKAGVNVLTYGNFLTILINFIILAWVVFLMVKLINRMRRKQEEAPAAPAPTPEDIALLREIRDELKNRPQV
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RD23A_ARATH
Sequence: MKLTVKTLKGSHFEIRVLPTDTIMAVKKNIEDSQSKDNYPCGQQLLIHNGKVLKDETTLVENKVTEEGFLVVMLSKSKTASSAGPSSTQPTSTTTSTISSTTLAAPSTTQSIAVPASNSTPVQEQPTAQSDTYGQAASTLVSGSSIEQMVQQIMEMGGGSWDKETVTRALRAAYNNPERAVDYLYSGIPETVTIPATNLSGVGSGRELTAPPPSGGPNSSPLDLFPQEAVSDAAGGDLGTLEFLRGNDQFQQLRSMVNSNPQILQPMLQELGKQNPQLLRLIQENQAEFLQLLNEPYEGSDGDVDIFDQPDQEMPHSVNVTPEEQESIERLEAMGFDRAIVIEAFLSCDRNEELAANYLLEHSADFED
What is the function of this protein?
May be involved in nucleotide excision repair (By similarity).  Binds and presumably selects ubiquitin-conjugates for destruction.  Prefers multiubiquitin chains rather than single ubiquitins, with a binding affinity for 'Lys-48'-linked ubiquitin chains.  Acts as a ubiquitin receptor that associates with the 26S proteasomal docking subunit RPN10 for the indirect recognition of ubiquitinated substrates of ubiquitin/26S proteasome-mediated proteolysis (UPP) (By similarity).
What are the official names of this protein?
Probable ubiquitin receptor RAD23a, AtRAD23a, Putative DNA repair protein RAD23-2, RAD23-like protein 2, AtRAD23-2.
What is the protein family that this protein belongs to?
Belongs to the RAD23 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: TPIS_BORPE
Sequence: MTTAENRARLVLGNWKMHGNLAENAALLAELRAADAAAHCEMGVCVPFPYLAQTAAALQGSAIGWGAQDVSAHAKGAYTGEVAAPMLAEFGCRWVLVGHSERRTLHAESDQLVADKARAALEAGLTPVVCVGESLQEREGGNTLGVIERQLEPVLALGRDALVRMVLAYEPVWAIGTGRTASPEQAQEVHSAIRVALDGLQASQVRVLYGGSVKGANAASLFAMPDIDGGLVGGASLVAEEFLRIAAA
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CHESB
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRKYASVGDIIVVSVKEAIPRGRVKKGDVMKAVVVRTAKDIRRPDGSVIRFDSNAAVLVDNKREPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: URAD_HALJB
Sequence: MTRLTVEDLNQADKERFVDAVGDVYEESPWVAKRTWSEQPFSSIDGLQQAMANTVQDASQQKQLELLRAHPDLGERTEMTDESQEEQASAGLDRLPPAQYETFQTLNDTYRDKFGFPFIMAVKDESVGTIQQAMEDRIDHSRSKEFQTALNEVNVIAALRLEELTVPRDGTQEQHA
What is the function of this protein?
Catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.
What are the official names of this protein?
2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, OHCU decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the OHCU decarboxylase family.
Protein: NUDJ_ECOSM
Sequence: MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI
What are the official names of this protein?
Phosphatase NudJ.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudJ subfamily.
Protein: PUR5_PSYCK
Sequence: MSNKPSLSYKDAGVDIDAGDALVQRIKSVAKATSRPEVVGGLGGFGALCRIPTGYTSPLLVSGTDGVGTKLKLALQLNRHDTIGIDLVAMCVNDLLVCGAEPLFFLDYYATGKLDVDVAATVVTGIGEGCKLSNCALIGGETAEMPGMYQDDDYDLAGFCVGVVEEAEVITGENVAEGDVLIALASSGAHSNGYSLVRKVIEVSGVDVTSSNEQLDGQSIQDALMAPTRIYVKAIKALQDTLGSSALHAMSHITGGGLTDNLPRVLPETLAASIDTNSWQFSELFTWLQNQGNIEQSEMYRTFNCGVGFVIVVPKDKAEAAIQTLNDAGEKAWKLGEMVKREADAVVYR
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREE_LIMFE
Sequence: MVLTEVYRNVDDIPNIGSYHIETAMVKSDDLMKNILRVKTDHGNEYGIRLDNEDQILENGSAFKLGDKQLLVLSVIADEMIEITPRDINEMGLVAHFLGNLHKPVQIKDGKISLLLDKVVIKMLDKHDINYELKKVQLDQPLEYLDLTK
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.