PharMolix/UniProtQA huggingface dataset:
Protein: HSSS_STAHJ
Sequence: MFKTLYTRIAIYTITVILFSALVSFLFANVYYHFNLKAHNDAKIMRTLKEARAFHTSSNQSDTQSYFKHLGDMNYQIMIVDHSYHKTFFGEPFRKDTISDSAINQVLKGKAYHGIKNKPFELFITGFFDNETDNTVGIPFNQNNQKLAVFMRPDIGETFSEFRTFLAVLLICLLGISITLVIASTYSIIKPIKILKQATERLMHGDFNSPIYQSRHDEIGTLQYRFEAMRQSLKQVDDMRQHFVQNVSHEIKTPLTHIHRLLSTLQSNVNQGERDQIIHEIHEEVTHLSNLTKELLLLSELDNATHLKFEDDVHFKELITDIIRHEQYGIDNKQLMLMSDIDTVHFRGNNRLLHQACSNLIQNAIKYSNPNSMIDVNLFNNEGTIYFTVTNEGHTIPESVQPHLFDRFYKRNAEDNSNGLGLAITQSIIHLHRGQISVTSNDRDGTTFTVTLPETN
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR.  HssR/HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme sensor protein HssS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRPA_ECOL5
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGTPFSDPLADGPTIQNATLRAFAAGVTPAQCFEVLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAECEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKAFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: BIOB_AGRVS
Sequence: MSEAAGEIRNDWSVEEIVTLHNLPLLELIGHANAVHGRHHNPNVVQKASLLSIKTGGCPEDCAYCPQSAHHREVKLTKDRLMQPETVLALAKRAKDAGAERFCMGAAWRQVRDGKEFDAVLTMVRGVRDLGMEACVTLGMLEKHQAEKLAEAGLTAYNHNLDTSPEFYGEIITTRSYADRLETLSIVRSFGIDLCCGGIIGMGETIRDRASMLQVLASMRPHPESVPINALVPVEGTPLAAMPRIDPLELVRMVATARIVMPKSTVRLSAGRSTLNREAQILCLVSGANSVFYGDTLLTTPNAGIGEDEALFAAIGALPHEAAPLAAE
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: BACD3_MOUSE
Sequence: MEEMSGDSVVSSAVPAAATRTTSFKGASPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGGVPLPESRREIEELLAEAKYYLVQGLLEECQAALQNKDTYEPFCKVPVITSSKEEQRLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERERIERVRRIHIKRPDDRAHLHQ
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex.  The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3, mBACURD3, BTB/POZ domain-containing protein KCTD10.
What is the protein family that this protein belongs to?
Belongs to the BACURD family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_MYCLB
Sequence: MLEGCILPDFGQSKTDVSPSQSRPQSSPNNSVPGAPNRISFAKLREPLEVPGLLDVQTDSFEWLIGSPCWRAAAASRGDLKPVGGLEEVLYELSPIEDFSGSMSLSFSDPRFDEVKAPVEECKDKDMTYAAPLFVTAEFINNNTGEIKSQTVFMGDFPMMTEKGTFIINGTERVVVSQLVRSPGVYFDETIDKSTEKTLHSVKVIPSRGAWLEFDVDKRDTVGVRIDRKRRQPVTVLLKALGWTSEQITERFGFSEIMRSTLEKDNTVGTDEALLDIYRKLRPGEPPTKESAQTLLENLFFKEKRYDLARVGRYKVNKKLGLHAGELITSSTLTEEDVVATIEYLVRLHEGQSTMTVPGGVEVPVETDDIDHFGNRRLRTVGELIQNQIRVGMSRMERVVRERMTTQDVEAITPQTLINIRPVVAAIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGLEVRDVHPSHYGRMCPIETPEGPNIGLIGSLSVYARVNPFGFIETPYRKVVDGVVSDEIEYLTADEEDRHVVAQANSPIDEAGRFLEPRVLVRRKAGEVEYVASSEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMQRQAVPLVRSEAPLVGTGMELRAAIDAGHVVVAEKSGVIEEVSADYITVMADDGTRRTYRMRKFARSNHGTCANQSPIVDAGDRVEAGQVIADGPCTENGEMALGKNLLVAIMPWEGHNYEDAIILSNRLVEEDVLTSIHIEEHEIDARDTKLGAEEITRDIPNVSDEVLADLDERGIVRIGAEVRDGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGESGKVIGIRVFSHEDDDELPAGVNELVRVYVAQKRKISDGDKLAGRHGNKGVIGKILPAEDMPFLPDGTPVDIILNTHGVPRRMNVGQILETHLGWVAKSGWKIDVAGGIPDWAVNLPEELLHAAPNQIVSTPVFDGAKEEELQGLLSSTLPNRDGDVMVGGDGKAVLFDGRSGEPFPYPVTVGYMYIMKLHHLVDDKIHARSTGPYSMITQQPLGGKAQFGGQRFGEMECWAMQAYGAAYTLQELLTIKSDDTVGRVKVYEAIVKGENIPEPGIPESFKVLLKELQSLCLNVEVLSSDGAAIELREGEDEDLERAAANLGINLSRNESASIEDLA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CHH5_PENJP
Sequence: MKPGNTSFNMVSFRMVWTAMMATLLVAGASSAGTRSSEDLSAPEDRSLSKRLVFDPSCAGVYDRVLLGKLNRLCDDCYNVFREPNVATECRSNCFYNLAFVQCLEYLMPPSLHEEYQANVQMVGK
What is the function of this protein?
Hormone found in the sinus gland of isopods and decapods which controls the blood sugar level.  Has a secretagogue action over the amylase released from the midgut gland.  May act as a stress hormone and may be involved in the control of molting and reproduction.
What are the official names of this protein?
Crustacean hyperglycemic hormones 5, Pej-SGP-V.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRAP_STAEP
Sequence: MYLYTSYGTYQFLNQIKLNHQERSLFQFSTNDSSIILEESEGKSILKHPSSYQVIDSTGEFNEHHFYSAIFVPTSEDHRQQLEKKLLHVDVPLSNFGGFKSYRLLKPTEGSTYKIYFGFANRTAYEDFKASDIFNENFSKDALSQYFGASGQHSSYFERYLYPIEDH
What is the function of this protein?
Contributes to virulence and biofilm formation.
What are the official names of this protein?
Signal transduction protein TRAP, Target of RNAIII-activating protein.
What is the protein family that this protein belongs to?
Belongs to the TRAP family.
What are the subcellular locations of this protein?
Membrane. Note=Membrane-associated.
Protein: CC198_HUMAN
Sequence: MGLSHSKTHLRVIKVAPLQNKEVETPSAGRVDFAFNQNLEEKTSYSLARLQDQNKALEGQLPPLQENWYGRYSTASRDMYFDIPLEHRETSIIKRHPPQRLQKLEPIDLPRVITSGRLLSQREARTMHKAKQVLEKKMQTPMYTSENRQYLHKMQVLEMIRKRQEAQMELKKSLHGEARINKQSPRDHKAKKTLQSTPRNDDHDLLTMLPDEILNRGPGNSKNTEFLKHQAVNNYCPWKIGKMETWLHEQEAQGQLLWDSSSSDSDEQGKDEKKPRALVRTRTERIPLFDEFFDQE
What are the official names of this protein?
Uncharacterized protein CCDC198.
Protein: RL33_RHOPT
Sequence: MAKAVTIKIKLVSTADTGFYYVTKKNSRTMTDKMVKKKYDPVARKHVEFKEAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RL4_EHRCJ
Sequence: MEVSIINVNSDKIGTIDLNPLIFSVDYRPDILKMVVNWQLSKRRAGTHKAKTIGDISGTTAKPYRQKHTGRARQGSLRSPQFRGGAVIFGPVVRNHAYSLNKKVRKLGLKVALSLKNSCNKLLILDSIDVNFVKTTQVLQFIRNFEHKSFLIIDKDYNKNVVCSCRNLHNVTLLKQIGTNVLDILRHDCIILTVGAVKYLEERLL
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: FTSA_STAAC
Sequence: MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNGLIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEINGSHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAIQKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYERGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQVDSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKELLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDNEETEEDVIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQDKDKDKEESKFKKLMKSLFE
What is the function of this protein?
Cell division protein that is involved in the assembly of the Z ring.  May serve as a membrane anchor for the Z ring.
What are the official names of this protein?
Cell division protein FtsA.
What is the protein family that this protein belongs to?
Belongs to the FtsA/MreB family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.
Protein: PIGO_MOUSE
Sequence: MRKVSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGACWMPSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGDDTWRDLFPGAFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDGGSWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLENDTLLVVAGDHGMTMNGDHGGDSELEVSAALFLYSPTALFPSVPPEEPEVIPQVSLVPTLALLLGLPIPFGNTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQVSRFLHTYSAATQDLQVKELHRLQTLFSKASARYQHFLRDPQEAEAALSTLTAEFQQFLRGARALCIESWARFSLVRMAGGAALLAAACLLCLLASQLAVAPGFLFRPLLLIPVAWGLTWTILYAGVSVTTGSKIDLVVLGAVAAAGSLLPFLWKAWVSRGSKRPLAPLLPVPRPVLILLLIRLATFFSDSFFVVEARATPFLLGSLVFFLVAQLHWEGQLLPPKPLTMSRLGSSAPTAPPRHSGAHALWLGIGLLLFTRLAGLFHRCPEETPACRSSPWLSPLASMVGGRAKNLWYGACVGALVALLVVVRLWLRRYGNLKSPEPPVLFVRWGMPLMVLGTAAYWALASGAEEAPPRLRALVAGASAVLPRAVMGLAALGLVLLLWRPVTVLVKAGAATSRTRTILTPFSGPPTSQADLDYVVPQIYRHMQEEFQGRLERTKAQGPITVAAYQLGSVYSAAMVTALLLLAFPLMLLHVERVSLVFLLLFLQSFLLLHLLAAGTPVATPGPFTVLWQAVSAWVLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCERQGPKRRQPLPGSESEARVRPEEEEELQEPLMEVRLRDAPNHFNAALLQLGLKYLFILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIALVMRVDVAVSSWFKKLVLAQQR
What is the function of this protein?
Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.
What are the official names of this protein?
GPI ethanolamine phosphate transferase 3, Phosphatidylinositol-glycan biosynthesis class O protein, PIG-O.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NSA2_CANGA
Sequence: MPQNDYIERHIKQHGRRLDYEERKRKREAREVHKVAEKAQKLTGWKGKQFAKKRYAEKVAMRKKIKAHEQSKAKGSSKPLADNGEALPTYLLDREQTNTAKAISSSIKQKRLEKADKFSVPLPKVRGISEEEMFKVVKTGKSKSKSWKRMITKHTFVGEGFTRRPVKMERIIRPSALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGMVTSGGKVVWGKYAQITNEPDRDGCVNAILLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CEMA_AMBTC
Sequence: MSKKKALTSLPYLASIVFLPWGISLSFNKSLEPWVTNWWNTSQYETLLNEIQENNVLERFIELEELFLLDEMIRDYPETHIQKLRIGIHKETIELVKMYNQDYIHIISHFSTNIMSFAILSAYSILGNEELVTLNSWVQEFFYNLSDTIKAFSILLLTDSCIGFHSPHGWELMIGSVYKDFGFSHNDQIISGLVSTFPVILDTILKYWIFHHLNRISPSLVVIYHSMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: HBB_RHEAM
Sequence: VQWTAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFASFGNLSSPTAILGNPMVRAHGKKVLTSFGDAVKNLDNIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFAKDFTPECQAAWQKLVRVVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SYDND_WOLPM
Sequence: MNCYKTHTCEELRKNDVEKEVTLSGWLYRKRDHGNLIFVDLRDFYGITQLVFNNDKDFFDEISNLKLESVITVTGIVEARTEDTVNSSISTGEIEVIVNNLRVESEVEFHFDEEIAKEERSILVSITGEQEYPENMRFKYRFLDLRREKVRNNIILRSQIIAELRKLMIERGFLEIQTPILTASSPEGARDYLVPSRLNPGKFYALPQAPQIFKQLLMVSGFDKYFQIAPCFRDEDARADRSPGEFYQLDLEMSFVTQEDIFQIIESTLYRVFAKFSRKSVDKDFPRITYKEAMLKYGSDKPDLRNPLLISDVTEIFRDSGFNIFKSNIERGMVVRAIPAPKTAEEPRSFFDKKIEHAQKEFGAKGLGYITFDKDGTAKGPIAKFLDENRLNHIREATNIEPGDSVFFASDKENEAANIAGKVRTLLGSELSLIDDNIFRFCWIIDFPYFVYDDKSKKIDFFHNPFSMPHGGLKDLEDKNPLDILAYQYDLVCNGIELSSGAIRNNKLDIMYKAFAIAGYSRGEVDTRFGALVRAFRFGVPPHGGIAPGVDRIVMLLADEPNIREVICFPMNQQGEDVLMGAPSKVEDKHLRELSLKVIE
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCAB1_BOVIN
Sequence: MKTPEAPPLAPDCLPSDQAPAPARLSRQASPMDKNTDPELMPTPRDGDDPPQVSSDPMVGLALSQELEEGVPASLPTPLESGFGSPSELSSRVEEKELSENVSLPAEETNRPELGPGEDVEGVSEELTPEDEGYTIWNYNFSQVPRFLSGSWSEFITQPENFLKGCKWAPDGSCILTNSADNILRIYNLPPELYNEGEQLEYAEMAPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRSYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTSRPGRDCEVRTTFAKRQGQSGIISCIAFSPTQPLYACGSYGRSLGLYTWEDGSPLALLGGHQGGITHLCFHPDGNCFFSGARKDAELLCWDLRQLGHPLWSLSREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTGGAGLESKPEPVLSFQPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEREEEVDLPLLSMRHVHLECQLQLWWCGGGPDTSISDAHQEEMGQGRTEGGGGEFT
What is the function of this protein?
RNA chaperone that plays a key role in telomere maintenance and RNA localization to Cajal bodies.  Specifically recognizes and binds the Cajal body box (CAB box) present in both small Cajal body RNAs (scaRNAs) and telomerase RNA template component (TERC).  Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes.  In the telomerase holoenzyme complex, required to stimulate the catalytic activity of the complex.  Acts by specifically binding the CAB box of the TERC RNA and controlling the folding of the CR4/CR5 region of the TERC RNA, a critical step for telomerase activity.  In addition, also controls telomerase holoenzyme complex localization to Cajal body.  During S phase, required for delivery of TERC to telomeres during S phase and for telomerase activity.  In addition to its role in telomere maintenance, also required for Cajal body formation, probably by mediating localization of scaRNAs to Cajal bodies.  Also plays a role in DNA repair: phosphorylated by ATM in response to DNA damage and relocalizes to sites of DNA double-strand breaks to promote the repair of DNA double-strand breaks.  Acts by recruiting the ubiquitin ligase RNF8 to DNA breaks and promote both homologous recombination (HR) and non-homologous end joining (NHEJ).
What are the official names of this protein?
Telomerase Cajal body protein 1, WD repeat-containing protein 79, WD40 repeat-containing protein antisense to TP53 gene homolog.
What is the protein family that this protein belongs to?
Belongs to the TCAB1 family.
What are the subcellular locations of this protein?
Nucleus, Cajal body. Chromosome, telomere. Chromosome. Note=Released from telomerase RNA template component (TERC) in mitotic cells coincident with delocalization from Cajal bodies. In response to DNA damage, localizes to sites of DNA double-strand breaks following phosphorylation by ATM.
Protein: KEFB_YERPE
Sequence: MEGTGLLTAVLVFLFAAVVAVPIAQRLGIGAVLGYLIAGIAIGPWGLGFIRDVDEILHFSELGVVFLMFIIGLELNPAKLWQLRRSIFGVGAGQVVITAAVLGALLYFTQFAWQAAVIGGVGLAMSSTAMALQLMREKGMNRNEGGQLGFSVLLFQDMAVIPALALIPILAGNEGGANDWVKIGLKIAAFAGMLIGGRYLLRPLFRYIVASGVREVFTAAALLVVLGSALFMDALGLSMALGTFIAGILLAESEFQHELEIAIEPFKGLLLGLFFISVGMALDLGVLFTHLLDVLLGVLALVFIKSAILYGLARVFGLRRSVRLQFAGVLSQGGEFAFVLFSAAFSQRVLNAEQLALLLVVVTLSMMTTPLLMQVIDRILVRRYNAQEESDEKPFVEDNDPQVIIVGFGRFGQVIGRLLMANKMRITVLERDVSAVSMMRKYGYKVYYGDATELELLRAAGAEKAKAIVITCNEPEDTMALVHLCQQHFPNLHILARARGRVEAHELLQNGVKDFTRETFSSALELGRKTLLELGMHPHQAYRAQQHFRRLDMRMLRELMPQHHGDVAQISRIKEARRELEDIFQREMLHESRQLDGWDEYE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS3_AZOVD
Sequence: MKDWLDEIHWNADGLVPAIAQDHRTGRILMMAWMNRESLALTVRENRAIYWSRSRGKLWRKGEESGHVQKVHELRLDCDADVIILQVEQLGGIACHTGRESCFYRVFEDGAWKVVDPILKDPDAIYRAGHPHE
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_ORYSJ
Sequence: MAVAGLLLRPPPCVAMCTPSPSPFPSSQRRRRRRLTLAQPYCTLGLSFVSGRHHRFLLRRRRRTESKRTSRGTGVYASLFGVGAPEALVIGVVALLVFGPKGLAEVARNLGKTLRAFQPTIRELQDVSREFRSTLEREIGLDEVPPSMNYRPPTMNNSQQPAIDQSSDDKPEAAPYTSEELIKVTEEQLAASAAAAWNTQEPPPSQQKEAAATSESNDGAISRGSDGAGAAMSEPNRNISEKTETER
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane.  Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation.  TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TATB, chloroplastic, Protein HIGH CHLOROPHYLL FLUORESCENCE 106, Protein TWIN-ARGININE TRANSLOCATION B.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein. Note=The C- terminus is located in the stroma.
Protein: BIOB_ANAMM
Sequence: MIRNNWTLEEALELFRMPFSDLILKAHSVHVQNFRNNEVQVAALMNIKTGSCPENCRYCAQSAHYNTGLEKKSLSTVEEVKTAAKRAKEIGADRFCFAAAWRNLHDRDLEKICQFVEAIKSEGLESCASLGMLKLDQAQKLKESGLDFYNHNVDTSREFYHNVVTTRTYEERLETVRNVQQAGIKVCCGGILGMGESTEDRASMLVTLANLEQHPLSVPINRLVPIEGTPMEGNPKIDNIDFVRTIAVARIMMPASYVRLAAGRGEMSEEMQALCMLAGANSIFCGEKLLTTPNARPEDDQRLFSQLGITPSRAACTTSDAQLA
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: NQRA_CHLTA
Sequence: MKIVVSRGLDLSLKGAPKESGFCGKVDPTYVSVDLRPFAPLPLGVKVTPEDQVTAGSPLAEYKLFSGVFITSPVDGEVVEIRRGNKRALLEIVIKKKPGISQTKFSYDLQSLTQKDLLEVFKKEGLFALFKQRPFDIPALPTQSPRDVFINLADNRPFTPSVEKHLSLFSSKEDGYYIFVVGVQAIAKLFGLKPHIISTDRLTLPTQDLVSIAHLHTIDGPFPSGSPSTHIHHIARIRNERDVVFTISFQEVLSIGHLFLKGFVLGQQIVALAGSALPPSQRKYLITAKGASFSDLLPKDIFSSDEITLISGDPLTGRLCKKEENPCLGMRDHTITLLPNPKTRESFSFLRLGWNKLTVTRTYLSGFFKRKRVFMDMDTNMHGEKRPIIDAEIYERVSAIPVPVALIIKALETQNFEEACRLGLLEVAPEDFALPTFIDPSKTEMFSIVKESLLRYAKENVVTSS
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: TRHO_RHOBA
Sequence: MTESHASSVPAELPAESPAEAGAADLPVAVAALYCFTPLPQFESLREPFRQRMSDDGIRGSLLLAGEGINGTIAGPRELMEPFIDWLRSMELDDQATPFRGMDVKWSYCEEIPFRKTKVRLKREIVTMGVSSIDPLRSVGTYIEPQDWNALVDDPDVTLIDTRNDYEIEIGTFEGAINPHTESFREFPKFVEENLDPQKHPKVAMFCTGGIRCEKSTAYLKERGFEEVYHLRGGILNYLEKMPEEDSRWQGECFVFDNRVAVDHQLQAGAYELCHGCGWPLTPEMKQHSDYERGVACSRCAAEVTYEQRKRRRMRQQQLDQGV
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: Y5004_BURA4
Sequence: MLVHIPNVLTPEQVSMLRDRLDRAGDAWVDGRATAGYTGAPVKRNQQIAEHSPVARELGDVILAALERNPLFISAALPNQVYPPLFNRYEGGMTFGSHVDGAVRVLPNGVKLRTDVSVTLFLSAPDEYDGGELVIEDAYGVQQVKLPAGDMIVYPATSLHQVTPVTRGVRVASFFWVQSLVRSDAQRALLFDMDTAIQRLNASGADTEACRSLVGCYHNLLRIWSET
What are the official names of this protein?
PKHD-type hydroxylase BamMC406_5004.
Protein: PNCB_ECO81
Sequence: MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLENKLVDFSALTAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: CFI_ARALP
Sequence: MSFSPVSPSQFPSVTKLQVDSVTFDPSVKSPASSNPLFLGGAGVRGLDIQGKFVIFTVIGVYLESNAVPSLSVKWKGKTTEELSESVPFFREIVTGAFEKFIKVTMKLPLTGQQYSEKVTENCVAIWKSLGIYTDCEAKAVEKFLEIFKEETFPPGSSILFALSPTGSLTVAFSRDDSIPETGIAVIENKLLAEAVLESIIGKNGVSPGTRLSIAERLAKLMTKNKVEEDASNHSIDEKLAKEN
What is the function of this protein?
Catalyzes the intramolecular cyclization of bicyclic chalcones into tricyclic (S)-flavanones.  Responsible for the isomerization of 4,2',4',6'-tetrahydroxychalcone (also termed chalcone) into naringenin (By similarity).
What are the official names of this protein?
Chalcone--flavanone isomerase, Chalcone isomerase.
What is the protein family that this protein belongs to?
Belongs to the chalcone isomerase family.