PharMolix/UniProtQA huggingface dataset:
Protein: GP17_BPPH5
Sequence: MNNYQLTINEVIEIINRNTDINKLVAKKDNLYPTDLYDLDKQQLIAIILNSDFALSSIKRALLEVTVEELREQDNDDDLDEIDNELYEGAEAADVPRETIVKVFEADKSIVTFNGEKLKHYVNVDDNSSSVDEVKKIAKEISEHDFNENKENK
What is the function of this protein?
Involved in the replication of viral DNA.  It is required at the very beginning of the virus amplification, conditions in which a low number of viral DNA molecules enter the host cell, possibly to recruit the limiting amount of initiation factors at the replication origins.  Once the infection process is established and the other replication proteins reach optimal concentration, it becomes dispensable.  Optimizes the binding of protein p6 at the viral DNA ends, thus favoring the initiation of replication.
What are the official names of this protein?
DNA replication protein 17, Gene product 17, gp17, Protein p17.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus protein p56 family.
Protein: YIDD_CLOAB
Sequence: MMRRILLKSIKFYRIYLSPLKRNACCKFIPTCSQYAIDAIEKYGALKGSFMAVKRILRCNPFSKGGYDPVK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ARI7_ARATH
Sequence: MDSEEDMLDAHDMESGEDDFYSGGTDDCNDSDDGEPDYGFVEEDADDSAMIASHRSQKNFCVLREEDIRRHQMDNIERVSVVLSITEVEASILLRHFHWSVGRVHDEWFADEERVRKTVGILESHVVPPSDDSELTCGICFDSYPPEKIASVSCGHPFCTTCWTGYISTTINDGPGCLMLRCPDPSCLAAVGHDMVDKLASEDEKEKYNRYFLRSYIEDNRKMKWCPAPGCDFAIDFVAGSGNYDVSCLCSFSFCWNCTEEAHRPVDCSTVSKWILKNSAESENMNWILANSKPCPRCKRPIEKNQGCMHMTCTPPCKYEFCWLCLGAWMDHGERTGGFYACNRYEVAKQEGQYDETERRREMAKNSLERYTHYYERWASNQTSRQKAMADLQQAQMQNLEKLSDKQCTPESQLKFILEAWLQIIECRRVLKWTYAYGYYLPEHEHAKRQFFEYLQGEAESGLERLHQCVEKDLVQFLIAEGPSKDFNDFRTKLAGLTSVTKNYFENLVKALENGLADVDSHAACSSKSTSSKSTGCSSKTRGKGKGSSRTGGSSRNPDDNL
What is the function of this protein?
Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase ARI7, ARIADNE-like protein ARI7, Protein ariadne homolog 7, RING-type E3 ubiquitin transferase ARI7.
What is the protein family that this protein belongs to?
Belongs to the RBR family. Ariadne subfamily.
Protein: PXMT1_ARATH
Sequence: MTTTPDWIMIGGDGPESYNQQSSYQRALLEATKDKMTKAISANLDLDLISNRFIVADFGCASGPNTFVAVQNIIDAVEEKYRRETGQNPADNIEFQVLFNDFSLNDFNTLFQTLPPGRRYFSAGVPGSFFERVLPKESFHIGVMSYAFHFTSKIPKGIMDRDSPLWNKDMQCTGFNPAVKKAYLDQYSIDTKILLDARAEELVPGGLMLLLGSCLRDGVKMSETPKGTVMDFIGESLSDLAKQGVTEQEKVDTFRTSIYFAEQGEIRQIIEENGKFTIEAFEDIIHAKNEFPFDPKTLAISFKAFYGAFISAHFGVEVMRKAFELVEVKAREQISRLHNSKPGMQYLIVLRKN
What is the function of this protein?
Methyltransferase that may methylate 1,7-paraxanthine (PubMed:26768601).  Prevents seed germination and modulates root architecture during early seedlings development (PubMed:26768601).  Plays a minor role in defense responses toward pathogenic bacteria (e. g.  P. syringae) (PubMed:28401908).
What are the official names of this protein?
Paraxanthine methyltransferase 1, SABATH methyltransferase PXMT1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. SABATH family.
Protein: PTP9_STYPL
Sequence: WQMIWQEKSPVVVMVTNVVELGKRKCHKYWPDESAQYGSIKVSQTHIEDLCDYTIRTFVIQQFDGYDVREVKQFHFTAWPDHGVPTRPTNILSFIRRVKSYETPGQGPTTV
What are the official names of this protein?
Tyrosine-protein phosphatase 9.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: CO1A2_HIPAM
Sequence: GPMGIMGPRGPPGASGAPGPQGFQGPPGEPGEPGQTGPAGARGPPGPPGKAGEDGHPGKPGRSGERGVVGPQGARGFPGTPGIPGFKGIRGHNGIDGIKGQPGAPGVKGEPGAPGARGIPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGPVGSPGASGPAGPRGEVGIPGVSGPVGPPGNGAAGIPGVAGAPGIPGPRGIPGPVGAAGATGARGIVGEPGPAGSKAGPQGIPGPSGEEGKRGSTGEIGPAGPPGPPGIRGSPGSRGIPGADGRAGVMGIPGSRGATGPAGVRGFPGSPGNIGPAGKEGPVGIPGIDGRPGPTGPAGARNIGFPGPKGPTGDNGDKGHAGIAGARGAPGPDGNNGAQGPPQGGKGEQGPAGPPGFQGIPGPAGTAGEAGKPGERGIPGEFGIPGPAGPRGERGPPGESGAAGPTGPIGNRGPSGPAGPDGNKGEPGVVGAPGTAGPSGPSGIPGERGAAGIPGPKGEKGEPGIRRDGARGAPGAVGAPGPAGANGDRGEAGPAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGTRGDGGPPGATGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGIRGPRGDQGPVGRSGETGASGPPGFAGEKTPGPQGIIGAPGFIGIPGSRGERGIPGVAGSVGEPGPIGIAGPPGARGPPGAVGNPGVNGAPGEAGRDGNPGSDGPPGRGHKGERGYPGAGAPGPQGPVGPTGKHGNRGEPGPAGVVGPTGAVGPRGPSGPQGIRGDKGEPGDKGPRGIPGIKGHNGIQGIPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPVGKDGRTGHPGAVGPAGIRGSQGPAGPPGPPGPPGPPGPS
What is the function of this protein?
Type I collagen is a member of group I collagen (fibrillar forming collagen).
What are the official names of this protein?
Collagen alpha-2(I) chain, Alpha-2 type I collagen.
What is the protein family that this protein belongs to?
Belongs to the fibrillar collagen family.
What are the subcellular locations of this protein?
Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
Protein: VPB12_SULTO
Sequence: MKTIMIRDDVYKKLLEIKGDKSFSEIIEELIEESLSVRRKKIEKYFGILNEEEARGLAKEIEEMRKRTDEDIARKLSNY
What is the function of this protein?
Possibly the antitoxin component of a type II toxin-antitoxin (TA) system.  Its cognate toxin is VapC12 (Potential).
What are the official names of this protein?
Putative antitoxin VapB12.
What is the protein family that this protein belongs to?
Belongs to the UPF0330 family.
Protein: DCUP_PSEMY
Sequence: MTALKNDRFLRALLKQPVDVTPIWMMRQAGRYLPEYRATRAKAGDFVSLMKNPELACEVTIQPLDRYPQLDAAILFSDILTIPDAMGQGLYFETGEGPRFKKAVGSLADIEALPVPDPEKDLGYVMDAVRTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKSKAMLYDNPQAMHALLDKLAQSVTAYLNGQILAGAQAVQIFDSWGGALSAAAYQEFSLAYMKKIVDGLIREHDGRRVPVILFTKGGGLWLESMADSGAEALGLDWTCDIGSARARVGSKVALQGNMDPAVLYAKPAAIRAEVARILAAYGAGSGHVFNLGHGITPEVDPAHAGAFFEAVHELSAAYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YS55_CAEEL
Sequence: MEYSYIPSAALYNNADIFQFFPRNKRLNSHQKSRLDEHARKMAAFMMERQEEYRYYENLANQEQFSDDNGMESGFCSGATSTGQSASTSPAPVQLIPNPFFDPEYVAAKTQSPVKLVTNPFFNPELVEEIKKKSQKRNEKSAPVSA
What are the official names of this protein?
Uncharacterized protein ZK673.5.
Protein: SIK1B_HUMAN
Sequence: MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGNFYKSGEPLSTWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIPFFMSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPAFSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNAQCARPGPARQPRPRSSDLSGLEVPQEGLSTDPFRPALLCPQPQTLVQSVLQAEMDCELQSSLQWPLFFPVDASCSGVFRPRPVSPSSLLDTAISEEARQGPGLEEEQDTQESLPSSTGRRHTLAEVSTRLSPLTAPCIVVSPSTTASPAEGTSSDSCLTFSASKSPAGLSGTPATQGLLGACSPVRLASPFLGSQSATPVLQAQGGLGGAVLLPVSFQEGRRASDTSLTQGLKAFRQQLRKTTRTKGFLGLNKIKGLARQVCQVPASRASRGGLSPFHAPAQSPGLHGGAAGSREGWSLLEEVLEQQRLLQLQHHPAAAPGCSQAPQPAPAPFVIAPCDGPGAAPLPSTLLTSGLPLLPPPLLQTGASPVASAAQLLDTHLHIGTGPTALPAVPPPRLARLAPGCEPLGLLQGDCEMEDLMPCSLGTFVLVQ
What is the function of this protein?
Probable serine/threonine-protein kinase.
What are the official names of this protein?
Putative serine/threonine-protein kinase SIK1B, Salt-inducible kinase 1B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.
Protein: SCPB_LIGS1
Sequence: MLSNQAKIESLLFISGNEGITLTELSQITGILKPALHEQLDKLADKYKQDRSSSLQLIHAEERYKLVTKPALAELVKKYLNSNNITELTGAALETLAIIAYKQPITRIGVDEIRGVQSSSMIQRLQLLELIKENGRLDAPGRPILYVTTDKFLDYFGLESLDQLPELDEEKQEDEEMDLMTLFEQTTGSTEDEEEE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: NRDR_DEHM1
Sequence: MNCPYCSHPDTKVIDSRDVDDGVRRRRECVVCGQRFTTYERFQPAGLFVVKKDQRREEFNKEKLLSGLRRACEKRPLPAGAVDKIAGDIEAELYNMGKAEIPSTLLGDMVMEKLKALDNIAYVRFASVYREFTDITQLKKVVDNLVSGQDEGIHKGQLSLLPEDRVSPKTRYQRR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: GPXA_NEIMC
Sequence: MGIYDFQMKDAEGNAVDLSGYRGKVLLIVNTATRCGLTPQYEALQKLYAQYTAEGLEILDFPCNQFREQAPESSGEIAQVCMMKFGTKFKIFDKIEVNGANTAPLYAYLKSVKPQDKGNHLFKDFVLKLAALGEKRDEGDIKWNFTKFLVNRDGEVVERFAPSVTPEEIEADIRALL
What is the function of this protein?
Important in the cellular metabolism or defense processes particular to this pathogen.
What are the official names of this protein?
Glutathione peroxidase homolog.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
Protein: GATA_BORAP
Sequence: MDLSNLTLTKIQELVLTKKCKIYDILLAYKNNYELNKDINGYIEFFDDSLEIAKRYDDFLRNCELEDLPLIGMLIAVKDNISIQDKSLTCASEILKGYISPYDATVIKRLKNKGAILIGRTNMDEFAMGSTCEFSYYGATLNPLNREYVIGGSSGGSAAVVAAFQAPFSLGSDTGGSVRLPASFSGILGFKPSYGGLSRYGLASYASSFDQIGFFAHSIEDIALILKHTCGADKMDSTSVDIFDDFYPLKIESLQGKNLAVIKELGEDLMDKNVASSFAKFKFDLLSKGINIKEVSIEEINFILSIYYTISPVEASSNLARYTGLCYGKRMSENLSLNDFYFKHRSNFLSEEVKRRIVLGNYLLSEGYDSKYYSKACEILQNLIIPKFNKLFESCDFIITPTSFVKPFRAGLDFDDPVKMYYSDICTVIANLIGAPAISLPYSKDKEGLSIGMQIIGRSKKDFELLSFSKNVIRELGLNGI
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MNTP_CAMJ8
Sequence: MDFYSLIFLSCALGMDAFAVSLCKGFSVKKLHLKHYLIVGIYFGGFQALMPTIGYFIGITFASFIASIDHWIAFILLSLIGLKMIKESLENENCDSNANQFGFKTMLALAIATSIDALAVGVSFAFLNVNLLLAIFLIGIITFILCIIALKIGNKFGIYLKNKAELLGGLVLIILGVKILIEHLFFD
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBP42_HUMAN
Sequence: MTIVDKASESSDPSAYQNQPGSSEAVSPGDMDAGSASWGAVSSLNDVSNHTLSLGPVPGAVVYSSSSVPDKSKPSPQKDQALGDGIAPPQKVLFPSEKICLKWQQTHRVGAGLQNLGNTCFANAALQCLTYTPPLANYMLSHEHSKTCHAEGFCMMCTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQEDAHEFLQYTVDAMQKACLNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKAAQSVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRFANFTGGKIAKDVKYPEYLDIRPYMSQPNGEPIVYVLYAVLVHTGFNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLSQQAYVLFYIRSHDVKNGGELTHPTHSPGQSSPRPVISQRVVTNKQAAPGFIGPQLPSHMIKNPPHLNGTGPLKDTPSSSMSSPNGNSSVNRASPVNASASVQNWSVNRSSVIPEHPKKQKITISIHNKLPVRQCQSQPNLHSNSLENPTKPVPSSTITNSAVQSTSNASTMSVSSKVTKPIPRSESCSQPVMNGKSKLNSSVLVPYGAESSEDSDEESKGLGKENGIGTIVSSHSPGQDAEDEEATPHELQEPMTLNGANSADSDSDPKENGLAPDGASCQGQPALHSENPFAKANGLPGKLMPAPLLSLPEDKILETFRLSNKLKGSTDEMSAPGAERGPPEDRDAEPQPGSPAAESLEEPDAAAGLSSTKKAPPPRDPGTPATKEGAWEAMAVAPEEPPPSAGEDIVGDTAPPDLCDPGSLTGDASPLSQDAKGMIAEGPRDSALAEAPEGLSPAPPARSEEPCEQPLLVHPSGDHARDAQDPSQSLGAPEAAERPPAPVLDMAPAGHPEGDAEPSPGERVEDAAAPKAPGPSPAKEKIGSLRKVDRGHYRSRRERSSSGEPARESRSKTEGHRHRRRRTCPRERDRQDRHAPEHHPGHGDRLSPGERRSLGRCSHHHSRHRSGVELDWVRHHYTEGERGWGREKFYPDRPRWDRCRYYHDRYALYAARDWKPFHGGREHERAGLHERPHKDHNRGRRGCEPARERERHRPSSPRAGAPHALAPHPDRFSHDRTALVAGDNCNLSDRFHEHENGKSRKRRHDSVENSDSHVEKKARRSEQKDPLEEPKAKKHKKSKKKKKSKDKHRDRDSRHQQDSDLSAACSDADLHRHKKKKKKKKRHSRKSEDFVKDSELHLPRVTSLETVAQFRRAQGGFPLSGGPPLEGVGPFREKTKHLRMESRDDRCRLFEYGQGKRRYLELGR
What is the function of this protein?
Deubiquitinating enzyme which may play an important role during spermatogenesis.
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 42, Deubiquitinating enzyme 42, Ubiquitin thioesterase 42, Ubiquitin-specific-processing protease 42.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: ISPE_GEOSL
Sequence: MKKLTLKAPAKVNYRLDVLRRRPDGYHDLRMIMQRIDLCDEIEICLTDGPGIRVVCGREGVPDGPGNIAWRAADALLALSADKPGIDISITKKIPVAAGLGGGSSDAATVLMGVNELLGLDLPEKRLREIGVTLGADVPFFIFGRTALAEGIGEELTAIDRVPAAWIVVVNPNVPVSTAWVYQNLQLTGEAARVKIPRFFESVAEVCAILSNDLESVTIPRYPVIGEIKRELLAAGALGSLMSGSGPTVFALFEEEDAAVRAAEMMRARSWFAAAVRTI
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: CR021_HUMAN
Sequence: MRQKHYLEAAARGLHDSCPGQARYLLWAYTSSHDDKSTFEETCPYCFQLLVLDNSRVRLKPKARLTPKIQKLLNREARNYTLSFKEAKMVKKFKDSKSVLLITCKTCNRTVKHHGKSRSFVSTLKSNPATPTSKLSLKTPERRTANPNHDMSGSKGKSPASVFRTPTSGQSVSTCSSKNTSKTKKHFSQLKMLLSQNESQKIPKVDFRNFLSSLKGGLLK
What are the official names of this protein?
UPF0711 protein C18orf21, HBV X-transactivated gene 13 protein, HBV XAg-transactivated protein 13.
What is the protein family that this protein belongs to?
Belongs to the UPF0711 family.
Protein: NDK_STRPS
Sequence: MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEELIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTIRGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAC_SORBI
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLRSETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: TRET_PYRHO
Sequence: MMYEVKEFSSGKRKLEDYKSIIGEEEVSKIQEKAEKLKGRSFVHVNSTSFGGGVAEILHSLVPLLRSIGIEARWFVIEGPTEFFNVTKTFHNALQGNESLKLTEEMKELYLNVNRENSKFIDLSSFDYVLVHDPQPAALIEFYEKKSPWLWRCHIDLSSPNREFWEFLRRFVEKYDRYIFHLPEYVQPELDRNKAVIMPPSIDPLSEKNVELKQTEILRILERFDVDPEKPIITQVSRFDPWKGIFDVIEIYRKVKEKIPGVQLLLVGVMAHDDPEGWIYFEKTLRKIGEDYDVKVLTNLIGVHAREVNAFQRASDVILQMSIREGFGLTVTEAMWKGKPVIGRAVGGIKFQIVDGETGFLVRDANEAVEKVLYLLKHPEVSKEMGAKAKERVRKNFIITKHMERYLDILNSLGG
What is the function of this protein?
Synthesizes trehalose from ADP-, UDP- or GDP-glucose and glucose.
What are the official names of this protein?
Trehalose synthase, Trehalose-synthesizing glycosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: DTPD_SHIFL
Sequence: MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSFLYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGYAQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVLLVATPALITVLFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFFSMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKESVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAELFIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINYSINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES
What is the function of this protein?
Probable proton-dependent permease that transports dipeptides.
What are the official names of this protein?
Dipeptide permease D.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family. DtpD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_STRP8
Sequence: MTDMRRLGQRAKQASLLIAPLSTQIKNRFLSTLAKALVDDTQTLLAANQKDLANAKEHGISDIMMDRLRLTSERIKAIAQGVQQVADLADPIGQVIKGYTNLDGLKILQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALHSNKALVKLIRQSLEKSGITPDAVQLVEDPSHAVAEELMQATDYVDVLIPRGGAKLIQTVKEKAKVPVIETGVGNVHIYVDAQADLDMATNIVINAKTKRPSVCNAAEGLVIHEAVAARFIPMLEKAINQVQPVEWRADDKALPLFEQAVPAKAEDFETEFLDYIMSVKVVSSLEEAISWINQHTSHHSEAIITRDIKAAETFQDLVDAAAVYVNASTRFTDGFVFGLGAEIGISTQKMHARGPMGLEALTSTKFYINGDGHIRE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VKTD_ANEVI
Sequence: MVFLLCFFLVADVSYGINGDCELPKVVGPCRASHPRYYYNSSSKRCEKFNYGGCRGNANNFHTLEECEKVCGVRSRDSPKEN
What is the function of this protein?
Serine protease inhibitor that inhibits both tissue and plasma kallikreins.  Has hemolytic activity.  Inhibits voltage-gated potassium channels (Kv).
What are the official names of this protein?
U-actitoxin-Avd3p, U-AITX-Avd3p, AsKC13.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. Sea anemone type 2 potassium channel toxin subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: MRAY_CERS5
Sequence: MLYTLTAFSDGGDIFNLFRYLTFRAGAAFFTALIFGFLFGRPLIDFLRRKQGKGQPIRDDGPATHFAKAGTPTMGGLLILSSLVVSTLLWARLDNPYVWIVLLVTVAFGLIGFADDYAKVKKQNTKGVSGRVRFVIGLVIAALAATAAAWSHPPDLTLQLAMPFFKDALVNLGWFFVPFAMVVIVGAANAVNLTDGLDGLAIMPVMIAGTTLGVIAYVVGNFNLTDYLGVHFVPGTGELLIFTSALVGGGLGFLWYNAPPAAVFMGDTGSLALGGALGAIAVCTKHEIVLAIVGGLFVTEALSVIIQVLYFKRTGRRVFLMAPIHHHFEKKGWAEPQIVIRFWIISLILALIGLSTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ATPG_GRAFK
Sequence: MANLKELRSRITSVSSTMQITKAMKMVSASKLSKAQDAITQMRPYSEKLTQLLQDLSATLDDDAGSKYAEEREVKNVLIVAISSNKGLAGAFNTNIIKAVKYKAKNDYKAKNIDIYTVGKKANDILKKEYDIHKNNNEIYDDLSFENASAIAEELMQLFLDEKYDKIVLVYNQFKNAATQIVQHEQFLPIEQFDSEENKQLDYIFEPSKLEIVKDLIPKSLKMQLFKALRDSFASEHGARMTAMHKATENATELRDDLKLSYNKARQASITNEILEIVGGAEALNG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RGMA_HUMAN
Sequence: MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
What is the function of this protein?
Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system.  Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses.  Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition.  Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway.  It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.
What are the official names of this protein?
Repulsive guidance molecule A, RGM domain family member A.
What is the protein family that this protein belongs to?
Belongs to the repulsive guidance molecule (RGM) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CH10_CUPTR
Sequence: MNLRPLHDRVIVKRLDNETKTASGIVIPDNAAEKPDQGEVLAIGPGKKDDKGNNIALDVKVGDRVLFGKYAGQGVKVDGQELLVMREEDIMAVVNK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3587_BACHK
Sequence: MLEKTTRMNYLFDFYQSLLTQKQRSYMSLYYLDDLSLGEIAEEFDVSRQAVYDNIKRTEAMLEEYEEKLVLLQKFQERQRLVAKLKQLISEEEHVNEEMKQVVEAIEKLD
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein BT9727_3587.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.