PharMolix/UniProtQA huggingface dataset:
Protein: CH10_METPP
Sequence: MKLRPLHDRVIVKRLEQETKTASGIVIPDNAAEKPDQGEVLAVGPGKRNDKGDFIALNCKVGDRVLFGKYSGQTVKVDGDELLVMREEDLFAVVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFYC_BOVIN
Sequence: MSTEGGFGGAGSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVLFAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRDELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIIIAQPQQGQTTPVTMQVGEGQQVQIVQAQPQGQAQQAQSGTGQTMQVMQQIITNTGEIQQIPVQLNAGQLQYIRLAQPVSGTQVVQGQIQTLATNAQQITQTEVQQGQQQFSQFTDGQQLYQIQQVTMPAGQDLAQPMFIQSANQPSDGQAPQVTGD
What is the function of this protein?
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.  NF-Y can function as both an activator and a repressor, depending on its interacting cofactors (By similarity).
What are the official names of this protein?
Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC.
What is the protein family that this protein belongs to?
Belongs to the NFYC/HAP5 subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: LIPB_CAUVC
Sequence: MRRDDAAPVGWAVSTQPVPYPAAVAAMEARAAAIADGTAGELIWLLEHPPLYTAGVSAKAGDLIQPDRFPVFESGRGGQFTYHGPGQRVAYVMLDLTQRGRDVRAFVAALEAWIIDALAAFNVTGELREGRVGVWVERKGAGWSREDKIAAIGVKLRRWVSFHGISLNVEPDLSHFSGIVPCGQTEHGVTSLVDLGLPVTLDDADAALRASFSKVFGPVEDAEAPV
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_STAS1
Sequence: MLTVAIAKGRLLKSFITYLKQANEQELVDALEKRERQLLISVGSIQIVLVKGSDVPIYVEQGVADVGIVGSDILEEGNYTINNLVDLPFGDCHFALAAKPETSSFNKIATSYVKTARAYFEAQGIDVELVKLSGSIELACLVEMVDGIVDIVQTGTTLKSNGLVEKDTIKPINAKLITNKQSYFKKSSEIDAFLSTLEVSLIDHR
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_CHLCH
Sequence: MSVKDVAQKIEPKMKKCLEAFQHEITTIRTGKATTTLLDRVKVEAYGQQMPLKQVGNVSVQDAHTLMVQVWDKSMVSATEKAIRDANLGLNPAAEGQSIRVSIPPLTEERRKEFVKLTKKFGEDSKVSLRNLRRDMIQDIEKLEKAKAVSEDEKNKGKKDADDLLHKYEKLLMDMITAKEKEIMAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA3_BRADU
Sequence: MTTTTMAGTPVAPAAAKPWYKVLYVQVLIAIVLGAIVGWLWPTVATNDWIKALGDGFIKLIKMVIAPIIFCTVVSGIAHIQDAKKVGRIGVKALVYFEVVSTFALVIGLIIGNLVRPGAGFGNAAANEAAVATYAKQAAGQKSVDFVLHIIPDTVVGAFAQGEILQVLLFSVLFGFAIMSLGERGHTIRSFIDDAAHAVFGVISIVMRAAPIGAFGAMAYTIGKFGTGAILNLIGLIATFYVTAALFVFVVLGIIARLAGFSIFKFLAYIKDELLIVLGTSSSESALPSLMEKLERLGCSKSVVGLVVPTGYSFNLDGTNIYMTLATLFIAQALGFDLSFGQQLTILVVAMLTSKGASGITGAGFITLAATLAVVDPRLVPGMAIVLGIDKFMSECRALTNLCGNGVACVIVAWWEGELDRDKLNAGLSRQIDPTDMETAITTD
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein 3.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GSA_CAMJJ
Sequence: MTNKKAFKEACKFIAGGVNSPVRAFANVQSEPKFISHGKGAYIFDIDGNSYIDYVQSWGPLLFGHCDKDIQKACQKALHKGSSFGAPTLLETELAKLVLSDFPHLEKIRFVSSGTEATMSAIRLARGFTKKDKILKFEGCYHGHSDSLLVSAGSGAATFNSPSSLGVLEDVAKHTLVAKYNDINSVKELFEKNKDIACVIIEPIAGNMGLVPAKQDFLEELAKICKNNQTLLIFDEVMSGYRASYLGSYGINHIQADIITFGKVIGGGLPAAAFASRAEIMDILSPLGGVYQAGTLSGNPLAMAAGIASLTKAKKKTKLYNKLGKLAKKLTQGMKKLADEKGLPLQACHVGSMFGYFFTKDPVSNYQDALKSDLALFSKFHKNMLENGIYLAPSQFETGFICSKMDDKIIDTTLEAVRESFKRI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_CAMHC
Sequence: MNFIFITLFENLIRPYFDDSILGRALKNEKIKIYFFNPRDFTANKYKKVDSYMIGGGAGLLINTEPLAETIKAVLENFNEVRFIFPTPAAKKFTQNDAKRLSKYKNLCFICGRYEGIDERIVEKYVNEVFCLGDFILTGGELAAMCFTDAIARNIKGVLGNEKSLDEESFENLLLEAPEFTKPDIFENLSINSEFLKGNHNKIQVLKNQMANSKTRFFRPDMFRKVIAKKGKK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AACT_PONAB
Sequence: MERMLPFLALGLLVAGFCPAVLCHPNCPLDEENPTQENQDRGTHVDLGLASTNVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILTGLRFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVEEQLSLLDRFMEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNRTRGKITDLIKDLDSQTMMVLVNYIFFKAKWKMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTTPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFRRIDELYLPKFSISRAFNLENILLQLGIVEAFTSKADLSGITGARNLVVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVDPMTIVRFNRPFLMIIVPTDTQNLLFISKVINPKQA
What is the function of this protein?
Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
What are the official names of this protein?
Alpha-1-antichymotrypsin, ACT, Serpin A3.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PP379_ARATH
Sequence: MAIASGSWVATVNHHANPHSFTSPTKPIFFLSQKPHNFHVCSSRCSMVLEEDEKKSPSPKEDKWPFFEPGPNDLNRVLSRFLRDPETRKLSSEFYEKAKENSELRTTKHLISYLVSSKSWDLLVSVCEDLREHKALPDGQTCSNLIRSCIRDRKFRITHCLLSVFRSDKSLAVSASDAAMKGFNKLQMYSSTIQVFDRLKQSVGVEPSPGCYCRIMEAHEKIGENHKVVELFQEFKSQRLSFLAKESGSIYTIVCSSLAKSGRAFEALEVLEEMKDKGIPESSELYSMLIRAFAEAREVVITEKLFKEAGGKKLLKDPEMCLKVVLMYVREGNMETTLEVVAAMRKAELKVTDCILCAIVNGFSKQRGFAEAVKVYEWAMKEECEAGQVTYAIAINAYCRLEKYNKAEMLFDEMVKKGFDKCVVAYSNIMDMYGKTRRLSDAVRLMAKMKQRGCKPNIWIYNSLIDMHGRAMDLRRAEKIWKEMKRAKVLPDKVSYTSMISAYNRSKELERCVELYQEFRMNRGKIDRAMAGIMVGVFSKTSRIDELMRLLQDMKVEGTRLDARLYSSALNALRDAGLNSQIRWLQESFDAAQTSTSKYSNTKNTGTLS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g13770, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FABD_SYNY3
Sequence: MKTAWVFPGQGSQAVGMGVDLLSTAIAKEKYQQAEEILGWSVVEKCQGDEASLALTQNTQPCLYVIEAILADLLRDKGFQPDYVAGHSLGEYSALYAAGVFDFATGLQLVKQRSEVMASASGGMMAALMKFDQTQLQQALTDNTEVVLANDNSPEQVVISGTVAGVEAILANVKARRAVPLKVSGAFHSSFMAQPSQSFAQTLTACHFNDATVPVLSNVDPSPTQNGDRLKEKLIQQMTGSVRWRETMVNLGEIGATDYWEVGPGKVLTGLCKRTCPDLNLKNIGQLDDLNSL
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.
Protein: MSH2_MOUSE
Sequence: MAVQPKETLQLEGAAEAGFVRFFEGMPEKPSTTVRLFDRGDFYTAHGEDALLAAREVFKTQGVIKYMGPAGSKTLQSVVLSKMNFESFVKDLLLVRQYRVEVYKNKAGNKASKENEWYLAFKASPGNLSQFEDILFGNNDMSASVGVMGIKMAVVDGQRHVGVGYVDSTQRKLGLCEFPENDQFSNLEALLIQIGPKECVLPGGETTGDMGKLRQVIQRGGILITERKRADFSTKDIYQDLNRLLKGKKGEQINSAALPEMENQVAVSSLSAVIKFLELLSDDSNFGQFELATFDFSQYMKLDMAAVRALNLFQGSVEDTTGSQSLAALLNKCKTAQGQRLVNQWIKQPLMDRNRIEERLNLVEAFVEDSELRQSLQEDLLRRFPDLNRLAKKFQRQAANLQDCYRLYQGINQLPSVIQALEKYEGRHQALLLAVFVTPLIDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLSELREVMDGLEKKMQSTLINAARGLGLDPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFSTVDIQKNGVKFTNSELSSLNEEYTKNKGEYEEAQDAIVKEIVNISSGYVEPMQTLNDVLAHLDAIVSFAHVSNAAPVPYVRPVILEKGKGRIILKASRHACVEVQDEVAFIPNDVHFEKDKQMFHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVSTFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISDYIATKIGAFCMFATHFHELTALANQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELANFPRHVIACAKQKALELEEFQNIGTSLGCDEAEPAAKRRCLEREQGEKIILEFLSKVKQVPFTAMSEESISAKLKQLKAEVVAKNNSFVNEIISRIKAPAP
What is the function of this protein?
Component of the post-replicative DNA mismatch repair system (MMR).  Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair.  When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs.  MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA.  MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long.  After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.  Recruits DNA helicase MCM9 to chromatin which unwinds the mismatch containing DNA strand.  ATP binding and hydrolysis play a pivotal role in mismatch repair functions.  The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone.  This transition is crucial for mismatch repair.  MutS alpha may also play a role in DNA homologous recombination repair.  In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
What are the official names of this protein?
DNA mismatch repair protein Msh2, MutS protein homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RPOB_HELAN
Sequence: MSTIPGFNQIQFEGFCRFIDQGLAEELSKFPKIEDTNQEIDFEFFLERYQLVEPLIKERDAVYESLTYSSELYVSARLIWKNDRRRYIQEQTILIGKIPIMTSLGAFIVNGIYRIVINQILQSPGIYYQSELNDNGISVYTGTIISDWGGRLELEIDRKARIWVRVSRQQKLSILVLLSAMGLNIREILENVCYPELFLSFLNDKKKIGSKENAILEFYQQFACVEGDPVFSESLSKDLQKKFFQQRCELGGIGRRNMNRRLNLDIPQNNTFLLPRDILAAADRLIRIKFGMGTLDDMNHLQNKRIRSVADLLQEQFGLALVRLENMARGNIYAALKHNWTPTPQNLVNSTPLTDTYKVFFRLHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTARTATFPIRDIHPSHYGRICPIDTSEGINVGLIGSLAIHARIGRWGSLESPFYQISERSKGAQMLYLSPGRDEYYMVAAGNSLALNQGIQEEQVVPARYRQEFLTIAWEQVQLRSIFAFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSQSEKCIVGTGLEGQAALDSGALAIAEHEGKIFYTDTDKILLSGNGDTLRIPLVMYQRSNKNTCMHQKPQVRRGKCIKKGQILAYGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQINQGPERVTNEIPHLEVHLLRNLDKNGIVMLGSWVETGDILVGKLTPQMVKESSYAPEDRLLRTILGMRVYTSKETCLKLPIGGRGRVIDVRWVQSSKTDETEKTESIRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFESSLGLAGDLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWIFEPESPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGRYSRLTQQPLKGRAKKGGQRVGEMEVWALEGFGVAYILQEMLTYKSDHIRARQEVLGTIIFGGRIPTPEDAPESFRLFVRELRSLALELNHFLVSEKTFQLNRKEA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FAEHP_METAR
Sequence: MYQIGEALIGEGNEVAHIDLLIGDKNGPVGIAFANGMTQLSMGHTPLLAVVRPNLIPKPATLIVPKVTVKNMGQAAQIFGPAQAAVAKAVADAVEEGVVPKDLCEDVVIIVSVFIHPEAQDPTKIYKYNYGATKLALTRAMEKFPGVDKVTYEKDRGVHAIMGYKITRLWDAPYLQIAIDAPDLGVVERVLKNVPKNDHLIIEAGTPLIKRYGLSVISKIREIRKDAFIVADLKTLDTGNLEARMAADNLADAVVCSGLAPIATIEKFIEEARKVGIYSIIDTLNVENPAKLIAALKVKPDIVELHRGIDTESQSAEHAWGNIPEIKKAAGGKKLLVAVAGGVKVENVETALKGGADILVVGRSITNAKDIEGESRRFLQAMKKDEIDQYRIMTDF
What is the function of this protein?
Catalyzes the reversible formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate.
What are the official names of this protein?
Bifunctional enzyme Fae/Hps.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily.
Protein: VM2I_CROBA
Sequence: AGEECDCGSPANPCCDAATCKLRPGAQCAEGLCCDQCRFIKKGKICRRARGDNPDDRCTGQSADCPRNHFHA
What is the function of this protein?
Inhibits fibrinogen interaction with platelets.  Acts by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) on the platelet surface and inhibits aggregation induced by ADP, thrombin, platelet-activating factor and collagen.
What are the official names of this protein?
Disintegrin basilicin, Basicilin, Platelet aggregation activation inhibitor.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CFA70_MACFA
Sequence: MEQVPSTGRLVQITVTEGYDLKGFKGDTPVTFIRAEFNQVVLGDSAKITVSPEGSAKYNFTSSFEFNPEGGITLDDLAHKPVFLTVTEVLPKEKKQKEEKTLILGQAVVDLLPLLEGQSSFQTTVPLHPVQGSPLETPRSSAKQCSLEVKVLVAEPLLTTAQISGGNLLKVTLEAAYSVPESFIPTGPGQNYMVGLQVPSLGEKDYPILFKNGTLKLGGEREPVPRPKKWPIANILAPGANNIPDAFIVGGPYEEEEGELNHPEDSEFRNQAECIKKRIIWDLESRCYLDPSAVVSFQKRIADCRLWPVEITRVPLVTVPKGKAGKTEKTDEEGQLSFHGVAYVNMVPLLYPGVKRIRGAFHVYPYLDSVVHEKTKCLLSLFRDIGHHLIHNNKIGGINSLLSKQAVSKNLKEDKPVKEKDIDGRPRPGDVQAPSIKSQSSDTPLEGEPPLSHNPEGQQYVEAGTYIVLEIQLDKALVPKRMPEELARRVKEMIPPRPPLTRRTGGAQKAVSDYHTQIKNISRAILDEYYRMFGKQVAKLESDMDSETLEEQKCQLSYELNCSGKYFAFKEQLKHAVVKIVREKYLKTTSFESQEELQTFISELYVFLVDQMHVALNQTMPDDVQGTIATIFTSSEQLRLFAFEAEVNENFEMAAAYYKERLVREPQNLDHWLDYGVFCLLTEDNIKAQECFRKALSLNQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNVVAWTLLGLYYEIQNNDIRMEMAFHEASKQLQAQMLQAQVTKQKSAGVVEDVEERGKRESSLGPWGITNGSATAIKVEAPAGPGAALSILDKFLEESSKLQSDSQEPILTTQTWDPSINQKPSNTFIKEIPTKKEACYERTISFVVDASEMHFIFLRLGLIYLEEKEYEKAKKTYMQACKRSPSCLTWLGLGIACYRLEELTEAEDALSEANALNNYNAEVWAYLALVCLKVGRQLEAEQAYKYMIKLKLKDEALLAEIHTLQETVGFGNPSF
What is the function of this protein?
Axoneme-binding protein that plays a role in the regulation of ciliary motility and cilium length.
What are the official names of this protein?
Cilia- and flagella-associated protein 70.
What is the protein family that this protein belongs to?
Belongs to the CFAP70 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, flagellum basal body. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Note=Present all along the flagellum, with a marked signal at the base of the flagellum.
Protein: DAPD_ACIBS
Sequence: MSQLSTIIEQAFEDCANFTAADCPSEIRQAVEEAIAGLDNGTLRVAEKINGEWVVHQWLKKAVLLSFKLNDNKPIESCDLRFYDKVETKFSGWTEEQFKAAGVRVVPPAVARRGSFQAKNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTRIYDRETGEIHYGRVPAGSVVVPGNLPSADGKYSLYAAIIVKKVDAQTRAKTSLNDLLRAD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTCR_ECOLI
Sequence: MRKTVAFGFVGTVLDYAGRGSQRWSKWRPTLCLCQQESLVIDRLELLHDARSRSLFETLKRDIASVSPETEVVSVEIELHNPWDFEEVYACLHDFARGYEFQPEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGPGEVTIIDLDLSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTGAGKSFLARRILELKQARHQFSGAFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREGLLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDLRQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHASLTGDSVRFNTEARRAWLAFATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQESRPSALTALLGAEAENIDLFDRMQLEHVIAICRQAKSLSAAGRQLFDVSRQGKASVNDADRLRKYLARFGLTWEAVQDQHSSS
What is the function of this protein?
Transcriptional repressor of the rtcAB genes.  Interacts with sigma-54.
What are the official names of this protein?
Transcriptional regulatory protein RtcR.
Protein: SPP24_SHEEP
Sequence: MEKMVMKMLVIFVFGMNHWTCTGFPVYDYDPASLKEALSASVAKVNSQSLSPYLFRAFRSSIKRVNALDEDSLTMDLEFRIQETTCRRESEADPATCDFQRGYHVPVAVCRSTVRMSAERVQDVWVRCHWSSSSGSSSSEEMFFGDILGSSTSRNSHLLGLTPDRSRGEPLYERSREMRRNFPLGNRRYSNPWPRARVNPGFE
What is the function of this protein?
Could coordinate an aspect of bone turnover.
What are the official names of this protein?
Secreted phosphoprotein 24, Spp-24, Secreted phosphoprotein 2.
What is the protein family that this protein belongs to?
Belongs to the SPP2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SCP2_BRALA
Sequence: GLNDFQKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDEWRDLKGRADINKDDVVSWEEYLAMWEKTIATCKSVADLPAWCQNRIPFLFKGMDVSGDGIVDLEEFQNYCKNFQLQCADVPAVYNVITDGGKVTFDLNRYKELYYRLLTSPAADAGNTLMGQKP
What is the function of this protein?
Like parvalbumins, SCPs seem to be more abundant in fast contracting muscles, but no functional relationship can be established from this distribution.
What are the official names of this protein?
Sarcoplasmic calcium-binding proteins II, V, VI, and VII, SCP II, SCP V, SCP VI, SCP VII.
Protein: ACYP2_RAT
Sequence: MAEPLKSVDYEVFGTVQGVCFRMYTEGEAKKRGLVGWVKNTSKGTVTGQVQGPEEKVNSMKSWLSKVGSPSSRIDRADFSNEKTISKLEYSNFSIRY
What is the function of this protein?
Its physiological role is not yet clear.
What are the official names of this protein?
Acylphosphatase-2, Acylphosphatase, muscle type isozyme, Acylphosphate phosphohydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: AROA_MYCPA
Sequence: MTTWTAPLAPQPVHATVTVPGSKSQTNRALVLAALAAAQGRGTPTLSGALRSRDTDLMIGALRTLGLRVDGTGPELTVSGHIAPGPHARVDCGLAGTVLRFVPPLAALADAVVEFDGDEQARARPIAPLLDALRGLGVRIEGTALPFRVHGSGALAGGTVAIDASASSQFVSGLLLCAASFTEGLTVQHTGAALPSAPHIAMTVAMLRQAGVDVDDSVPNRWQVRPGPVAARHWEVEPDLTNAVPFLAAAVVSGGTVRITGWPADSVQPADNILSVLGKLNAVVSQTDSSLEVRGSGSYDGFDVDLRAVGELTPSVAALAALATPGSVSRLSGIAHLRGHETDRLAALSAEINRLGGDCTETPDGLVITATPLRPGVWHAYADHRMAMAGAIVGLRVAGVRVDDIGATSKTLPDFPRLWARMLDASLPDGEEHGM
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL307_YEAST
Sequence: MSLRNISMITKNLQTTAKCYVPKSSPTSTTIPVIRDASTTQCRRITTVINITSLKGYSPSPRTVHDKPIVICTDNEEVETVSEHVKV
What are the official names of this protein?
Uncharacterized protein YLR307C-A.
Protein: LPXK_GLUDA
Sequence: MHAPRFWSGGDGGWPARLLAPAAALYTLATARRMRGTGWRAPVPVLCCGNLTAGGAGKTTVALDLAARLVARGRHVHILTRGYGGRARGPLLVDPARHSAAEVGDEALLLARVAPCHVSADRAAGARAAVAAGADCLVMDDGFQNPGLRQDMGLLVIDGGSGFGNGHVLPAGPLREPVAQGCRRARAAILIGGDRTGALAHLPPALPVLRADLAMQEAAPMLAGRPAIAFAGIGRPDKFFDGLRAQGIRLAACLPFPDHHAYRPRDVRRLSAMAAVQGAVLLTTPKDAVRLPPAIRAQVRSVDVTLAWADPMAPERLLDMWLDKASS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: RRF_RUEPO
Sequence: MSDDFELDTDDLKRRMDGAMANLKTEFASLRTGRASGSMLEPIQVEAYGQMTPINQIGTVNVPEPRMVTINVWDKSMVGKVEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTKVAGQYAEHARVAIRNVRRDGMDQIKKAKADGISEDDQKFWEAEVQELTDKMIKVVDAALETKQAEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRA1_CANAL
Sequence: MNYLLFCLFFAFSVAAPVTVTRFVDASPTGYDWRADWVKGFPIDSSCNATQYNQLSTGLQEAQLLAEHARDHTLRFGSKSPFFRKYFGNETASAEVVGHFDNVVGADKSSILFLCDDLDDKCKNDGWAGYWRGSNHSDQTIICDLSFVTRRYLTQLCSSGYTVSKSKTNIFWAGDLLHRFWHLKSIGQLVIEHYADTYEEVLELAQENSTYAVRNSNSLIYYALDVYAYDVTIPGEGCNGDGTSYKKSDFSSFEDSDSGSDSGASSTASSSHQHTDSNPSATTDANSHCHTHADGEVHC
What is the function of this protein?
Cell surface protein involved in the host-parasite interaction during candidal infection.  With MP65, represents a major component of the biofilm matrix.  Sequesters zinc from host tissue and mediates leukocyte adhesion and migration.  As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation.  As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance.  Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation.  Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2.  Decreases complement-mediated adhesion, as well as uptake of C. albicans by human macrophages.
What are the official names of this protein?
pH-regulated antigen PRA1, 58 kDa fibrinogen-binding mannoprotein.
What is the protein family that this protein belongs to?
Belongs to the ZPS1 family.
What are the subcellular locations of this protein?
Secreted. Note=Found primarily on the cell surface of filamentous forms and enriched at hyphal tips.