PharMolix/UniProtQA huggingface dataset:
Protein: CTTB2_DASNO
Sequence: MATDGASCEPNFSRAPEDVGATAEAAVATKEFDVDTLSKSELRMLLSVMEGELEARDLVIEALRARRKEVFIQERYGRFNLNDPFLALQRDYEAGAGEKEKKPVCTNPLSILEAVMAHCRKMQERMSTQLAAAESRQKKLEMEKLQLQALEQEHKKLATRLEEERGKNKHVVLMLVKECKQLSGKVIEEAQKLEEVMTKLEEEKKKTNELEEELSAEKRRSTEMEAQLEKQLSEFDIEREQLRAKLNREEAHTTDLKEEIDKMKKMIEQLKRGNDSKPSLSLPRKTKDRRLVSISVGTEGPVTRSVACQTDLVIESTDHVKKLPLTVPVKPSTGSPLVSAPAKGNVCPSVPLLRPGIDRQASHGDLIVSSVPAVPPPNANRIEENGPSIGSTPDLASSTPPLPSNAAPPTGQTSGIASQNYSQASSMHSLHSPCANASLHPGPNPRIQAARFRFQGNANDQDQNGNTTQSPPSRDVSPTSRDNLVAKQLARNTVTQALSRFTSPQASASPRPGAPPTGDIGTHPAVSRTSLKTPGLARVDRGNPPPIPPKKPGLSQAPSPPHPQLKAIMDSSRASNAGAKVDNKTVASPPASLPQGNRVINEENLPKSSSPQLPPKPSIDLTVAPAGCAVSALATSQVGARPAETPGPTQPACSDSSLVIPTTIAFRSSINPVSASASRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRPTLLQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLNAKAQIDAADKNGFTPLCAAAAQGHFECVELLIAYHANIDHAADGGQTPLYLACKNGNKECIKVLLEAGTDRSVKTRDGWTPVHAAVDTGNVDSLKLLMYHRAPTLGHSLNEEEPEPGAFDLDQGQEGSEGTAKPVVPTDLINHANREGWTAAHIAASKGFKNCLEILCRHGGLEPERKDKCNRTVHDVATDDCKHLLENLNALKIPLRISVGETQPGSYGCDDFECENTICALNIHKQTSWDDFSKAVSQALTNHFQAISSDGWWSLEDMTFNNTPEPSIGLSARSILSITLGNVPWSAGQCFTQAPWDFMRKNKAEQVTVLLSGPQEGCLNSVTYASMIPLQMLQNYLRLVEQYHNVIFHGPEGSLQDYIAHQLALCMKHRQMAAGFSCEIVRAEVDAGFSKEQLIDLFINSACLIPVKQSPVTKKIIIILENLEKSSLSELLGDFLAPLENRSTESPCTFQKGNGTSECYYFHENCFLMGTIAKTCLQGSDLLVQQHFRWVQLRWDGEPMHGLLQRFLRRKVVNKFRGQAPSPCDPVCKMVDWALAVWHQLNSCLARLGTPDALLGPKYFLSCPVVPGHAQVTVKWMSKLWNAIIAPKVQEAILSRASVKRQPGLRQTTAKKPPSQGQQAVVKAALSILLNKAVLHGCPLLRAELDQYITDFKGGSFPLSIVSSYNSCSKKKGENGAWRKVSTNPRKKSGRFSSPTWSKPDLGEEGTKNKTMSQPNCNRIASLSKQKSSENDPSSMLNLDQRLSLGSDDEADLVKELQSMCSSKSESDISKIADSRDDLRRFDSSENSPAFSAAINNLRMPVSQKEVSPVSSHQTTKRSTSTSKTELSVSRVKSFLPVPRSKVSQCSQNTKRSSSSSNTRQTELNNNSKEEIWNLCKNEQVQKPNK
What is the function of this protein?
Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
What are the official names of this protein?
Cortactin-binding protein 2, CortBP2.
What are the subcellular locations of this protein?
Cytoplasm, cell cortex. Cell projection, dendritic spine. Note=Remains associated with dendritic spines even after glutamate stimulation.
Protein: RTCA_RALSO
Sequence: MNNRLQPAPCIELDGAQGEGGGQILRTALTLSMLTGTPFRIERIRAGRSKPGLMRQHLTAVQAAAEVSGATVEGAEAGSQALAFAPGPIHGGDYRFAIGTAGSCTLVLQTVLPALWFADAPSTVAVSGGTHNRAAPPVDFLIRAWQPLLARMGVTQTLALKRHGFYPAGGGEVLATVTPCAGRLGALHLTERGALRELSGQGIVANVRPGVARRELEALAARVPGVVGSVRELSPAEGPGNALVLDAVHEHVTEVFTGFGERGVPAEQVAHGVASAALRYLHSTAAVDEYLADQLVLPMALAGAGCFTAVTASPHLTTNIAVIEKFLPVHITVQAERDASVVRVQVN
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STRA3
Sequence: MTLQDEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKSGTFAKSDWMDIEKQRGISVTSSVMQFDYAGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLDLLEELEEVLGIASYPMNWPIGMGKSFEGLYDLHNKRLELYKGDERFASIEDGDQLFANNPFYEQVKEDIELLQEAGNDFSEQAILDGDLTPVFFGSALTNFGVQTFLDTFLEFAPEPHGHKTTEGNVIDPLAKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMGVNLTRTGKGAKLSNVTQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPELFMKVSAKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMTPMGKKTVRWINSDDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVKLEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYA_PAEBA
Sequence: MKKMLTLLLSAGLVASIFGVMPAAAAPTVVNSTIVVPKGTTYDGQGKTFVANPSTLGDGSQAENQKPVFRLEAGATLKNVIIGAPAADGVHCYGSCNISNVVWEDVGEDALTLKSSGTVNITGGAAYKAYDKVFQMNASGTINIKNFRADDIGKLVRQNGGTSYAVNMTLDNSNISNVKDSIMRTDSSVSQGKITNTRYSKVPTLFKGFASGKTSQSGNTQY
What is the function of this protein?
Catalyzes the depolymerization of both polygalacturonate and pectins of methyl esterification degree from 22 to 89%, with an endo mode of action.  In contrast to the majority of pectate lyases, displays high activity on highly methylated pectins.  Is not able to cleave trigalacturonate.  Does not degrade xylans and carboxymethylcellulose (CMC).
What are the official names of this protein?
Pectate lyase A, Pectin lyase.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NFKI1_CAEEL
Sequence: MATVAPKGNCLVARAIPSDSHADQLTDLLCKLSVNGDANQKSVNKFESQHGVTPSDFRDIQNIRSSALAKKTKTSKFQLDGVTLFADLTPNSKSKKKTENQETKEKDEEAEEKKDGPPKDDKELKMKKEKEQEDENAELDEQKKDGDLLGRGPVHNVRVATGGSHPYHRAQIPYGCAAQTPITDISAYTGYGSGYECGSTWSLSPDTTIGSISASTTPDTVLSSDGYGSASPPQHSPKESLQSPFSDISSADTSRVLTPENNELPESLQDFILQYSNQYTKEESIRGRPPSADSGVSSPMSARSAPYASPHVPQGTCSGPTTPSFNQTRLSPRTSENGITAKQRLNAIIPESDLATGFHWACTTWKNVLTNRDADGDTPLHIVAAHNDLGKIYALCETLRKTMNENDDNVFNVSNNFGETPLYVAVLQRSIEVVEYLLELGASPNSRSSRAVGDSPLHFATARGMNNMVEALLSKREIRVNETNDDGQTSLLCAVKMHGMMDEQTQHKIDNKSIIEMLIKAGADPTIAETSTGKTIVHHAVDKMDVELLDFLKTVVNEDTFTELANLSDFHGDTAVDLLCSSTQNEDTNNVRENLYIRLLTSGAVPNKSRA
What is the function of this protein?
Acts downstream of the receptor complex composed of ilcr-1 and ilcr-2, which is a signaling complex that modulates neuronal activity and animal behavior in response to sensory neuron input.  Mediates signaling of the complex.
What are the official names of this protein?
ANK repeat-containing protein nipk-1.
What is the protein family that this protein belongs to?
Belongs to the iASPP family.
Protein: SYP71_ARATH
Sequence: MTVIDILTRVDSICKKYDKYDVDKQREANISGDDAFARLYGAFETQIETALEKAELVTKEKNRAAAVAMNAEIRRTKARLSEEVPKLQRLAVKRVKGLTTEELAARNDLVLALPARIEAIPDGTAGGPKSTSAWTPSSTTSRPDIKFDSDGRFDDDYFQESNESSQFRQEYEMRKIKQEQGLDMISEGLDALKNMASDMNEELDRQVPLMDEIDTKVDRATSDLKNTNVRLKDTVNQLRSSRNFCIDIVLLCIVLGIAAYLYNVLK
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway.
What are the official names of this protein?
Syntaxin-71, AtSYP71.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single- pass type IV membrane protein.
Protein: PPTA_PECCP
Sequence: MPHIDVKHFPRNLSEEEKKVIAEDLAAVLKKHFGSSDDSLSVAFNEIQPDRWKDEVYDPIIKPHLDTLAKKPGYSY
What are the official names of this protein?
Tautomerase PptA.
What is the protein family that this protein belongs to?
Belongs to the 4-oxalocrotonate tautomerase family. PptA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GIF1_MAIZE
Sequence: MQQQHLMQMNQNMMGGYTSPAAVTTDLIQQYLDENKQLILAILDNQNNGKAEECERHQAKLQHNLMYLAAIADSQPPQTAPLSQYPSNLMMQPGPRYMPPQSGQMMNPQSLMAARSSMMYAHPSLSPLQQQQAAHGQLGMAPGGGGGGTTSGFSILHGEASMGGGGAGAGAGNNMMNAGMFSGFGRSGSGAKEGSTSLSVDVRGGTSSGAQSGDGEYLKVGTEEEGS
What is the function of this protein?
Transcription coactivator that plays a role in the regulation of meristematic function in leaves, stems and inflorescences (PubMed:29437990).  Regulates shoot architecture and meristem determinacy (PubMed:29437990).  Binds to the inflorescence architecture gene UB3 (unbranched3) (PubMed:29437990).  Regulates the expression of several genes involved in inflorescence architecture (PubMed:29437990).  Component of a network formed by the microRNA396 (miRNA396), the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation (Probable) (PubMed:26036253).  Associates with the core SWI/SNF chromatin-remodeling complex and specific GRFs to tightly regulate the transition between cell division and cell expansion in growing leaves (PubMed:26036253).
What are the official names of this protein?
GRF-interacting factor 1, ZmGIF1, Protein ANGUSTIFOLIA 3 homolog.
What is the protein family that this protein belongs to?
Belongs to the SS18 family.
Protein: PKR1_BOVIN
Sequence: MEITMGVMDENATNTSTNYFPLLDPLGAQAASFPFNFSYGDYDMPLDEDEDMTNSRTFFAAKIVIGMALVGIMLVCGIGNFIFIAALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEMDYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKYQTATGLIALVWVVSILVAIPSAYFTTETVLVIVKSQEKIFCGQIWPVDQQIYYKSYFLFIFGIEFVGPVVTMTLCYARISRELWFKAVPGFQTEQIRKRLRCRRKTVLVLMCILTAYVLCWAPFYGFAIVRDFFPTVFVKEKHYLTAFYVVECIAMSNSMINTVCFVTVKNNTIKYFKKIMLLHWKASYNGSKSSGDLDLKTTGVPATEEVDCIGLK
What is the function of this protein?
Receptor for prokineticin 1.  Exclusively coupled to the G(q) subclass of heteromeric G proteins.  Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase.  May play a role during early pregnancy (By similarity).
What are the official names of this protein?
Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBL_ZYGCR
Sequence: MSPQTETKAGVGFKAGVKDYRLTYYTPDYETKETDILAAFRMTPQAGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVPGEENQYIVYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKINKYGRPLLGCTIKPKLGLSAKNYGRAVYEVLRGGLDFTKDDENVTSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMLKRAEYAKELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGEREVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNDVIREATKWSPELAAACEVWKEIKFEFDTIDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TMN3_ARATH
Sequence: MRLPTTLLLFIGALIFSGAGTVRSDASDHRYKDGDSVPLYANKVGPFHNPSETYRYFDLPFCIPEGVKDKKEALGEVLNGDRLVSAPYKLNFRDEKDSEVYCKKKLSREEVEHFRRAVEKDYYFQMYYDDLPIWGFIGKVDKESKSDPSEFKYFLYKHIQFEILYNKDRVIEINARMDPHSLVDLTEDKEVDAEFMYTVKWKETETSFEKRMDKYAMSSSLPHHLEIHWFSIINSCVTVLLLTGFLATILMRVLKNDFMKYAQDEEAADDQEETGWKYIHGDVFRFPKNKSLFAASLGSGTQLFTLTIFIFMLSLVGVFYPYNRGALFTALVVIYALTSGIAGYTASSFYCQLEGKNWVRNLLLTGGLFCGPLFLTFCFLNTVAIAYSATAALPFGTIIVIVLIWTLVTSPLLVLGGIAGKNSKAEFQAPVRTTKYPREIPPLPWYRSAVPQMAMAGFLPFSAIYIELYYIFASVWGHRIYTIYSILFIVFIILLIVTAFITVALTYFQLAAEDHEWWWRSFLCGGSTGLFIYAYCLYYYYARSDMSGFMQTSFFFGYMACICYGFFLMLGTVGFRAALLFVRHIYRSIKCE
What are the official names of this protein?
Transmembrane 9 superfamily member 3, Endomembrane protein 9, Transmembrane nine protein 3, AtTMN3.
What is the protein family that this protein belongs to?
Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: ANTRL_MOUSE
Sequence: MMSHSPSMPCSALFLLLLLLLPPTFKGGSLRYHGPGWKLFHRLSKGFRSSHQRQTQQMRQNVPQGQSGDDCQGIFDLYLVLDKSGSVADNWIHIYSFAEGLVKKFTNPNLRISIITYSTEAEVILPLTSDSKEINKSLLVLKNIVPQGLTHMQKGLRKANEQIRKSTLGGRIVNSVIIALTDGLLLLKPYLDTMEEAKKARRMGAIVYTVGVFMYSKQQLVNIAGDPDRCFGVDEGFSALEGVVDPLTSKSCTEILSVQPTYVCAKDFYQVNISGHGLNNTSNMKQVICRFKFSDSKVVDESPSDMNEHSITCPGPKIKHTGEDVSLQVSLNNGISFIGNKLIITSTNCWSPRASQGIVFKRTWLMFLPVLLVTLLLLCCTWKLCIKPKKLPPPPPKPEKEPEEESPPPSSPPAPGRGPGPGPSAGPGPGPGPSPGSGPARSPVPARPPPAPLPANTNPTVIVACCGCGNRGMQGNLDTCCDYFHPSCHPMPLVWCHPKAQGGYPGFAVMKPSCSQASCRQKHCLCSNRDCFHLAEPPYPTRIVFQPNEKYFSITQSHYSPKIRFQTNQESLPVAQTLCSKMCSPPNQECYTFKSPQSPYQARYTKSPARMLPLLPPHTRQSLESLCHTYPFPPISKGPKF
What are the official names of this protein?
Anthrax toxin receptor-like.
What is the protein family that this protein belongs to?
Belongs to the ATR family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GSDMC_MOUSE
Sequence: MSYTFDWLSKDVVKKLQGRDLRPVKCLSDATKFCLFNILQETSSRLALKTEYIPVGFTLLHLLEPNIPVPEPEVSAPIPLKHTISQKLKADLDVETIAGGEAGFVKSCGYDIEVQSKSIPNPKLESLQNRKLLDQLPTFMKTCWKDGKNLYVVTEAYEVTKDTVLEGTSNSKFAIKGIINQLVKVGGSGQWQTEKTDSIPIQKGSVLAYKKQQLVIEDNTCVILTSANTKKKMTFPMRFVGMSGHLRYQDLVIETGSWINDIDPIGTIKEPTHLDFMCLQNEVSEQTRLLAELSKDVQEVVFSSFLHMLCDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSLSWINLKDLILYLLQALMVLSDTQLCLLALSVEMRLLPHQVELVKSILQPNFKYPWNIPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLSEA
What is the function of this protein?
Pore-forming protein that causes membrane permeabilization and pyroptosis (By similarity).  Released upon cleavage and binds to membrane inner leaflet lipids.  Homooligomerizes within the membrane and forms pores of 10-15 nanometers (nm) of inner diameter, triggering pyroptosis (By similarity).  The functional mechanisms and physiological proteases that cleave and activate this pore-forming protein are unknown (By similarity).
What are the official names of this protein?
Gasdermin-C, Gasdermin-C1, Melanoma-derived leucine zipper-containing extranuclear factor, mMLZE.
What is the protein family that this protein belongs to?
Belongs to the gasdermin family.
What are the subcellular locations of this protein?
[Gasdermin-C]: Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Gasdermin-C, N-terminal]: Cell membrane; Multi-pass membrane protein.
Protein: MTNA_GEOSW
Sequence: MAEPFAIPRSVEWNDTHITILNQQKLPLVTEYLELKNIEDVWDAIAALKVRGAPAIGITAAYGLALSAQQYETESLEKFKEHVRKDRDYLASSRPTAVNLFWALDRLVSSIAHVSSVNEAKTTLIHEAIRIQIEDEDVCRRIGEHALSLFQNGDRVLTICNAGSIATARYGTALAPFYLAKEKGMNLHVYASETRPVLQGARLTTWELMQAGVDVTLITDNMAAQTIKAKNITAVIVGADRIAANGDTANKIGTFGLALLAKAFGIPFYVAAPLSTIDLATKTGEEIPIEERNPEEVTHIAGTRIAPEGVNVYNPAFDVTPHDLITAIITEKGIVRGNYETELPALFAKEARHEAI
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: DXR_HAEDU
Sequence: MKNIVILGATGSIGQSTLSVIEHNPDQYQVFALVGGKNVELMATQCSQFKPKFAALVDEKAAKLLAEQLKALNLTTQVLTGEQAICELAAHPDANIVMAAIVGAAGLLPTLAAVKAGKQILLANKESLVTCGQIFIDEARKSGATLLPVDSEHNAIFQSLPLVAQQKIGFCPLAELGVSRIILTGSGGPFREKSLAEFDSITPEQAIAHPNWSMGKKISVDSATMMNKGLEYIEARWLFNASVEEMEIIIHPQSIIHSMVRYIDGSVIAQMGNPDMRTPIAHTMAYPNRIPSGVMPLDFGKLTELTFIEPDFKRYPNLKLAIEASAEGQYATTALNAANEIAVDAFLNRQIRFTEIERINSTVVENIAPLRVNDVADVLHIDQLAREIAKQAMLNV
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: HSCB_SHEON
Sequence: MNYFELFKFPPTFDIDTAVLADRYRELQRAVHPDKFANDTEQQRLLSVQRTAQVNDGYQTLKDPIRRAEHMLSLRGIDLSHETTTVKDTAFLMQQMEWREALEDIRESIDHQAIINELYDSFAAYRLKLTKLLAAQLSSGSDEDALLAADQVRKLKFMAKLQDELTRIEDALLD
What is the function of this protein?
Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Seems to help targeting proteins to be folded toward HscA.
What are the official names of this protein?
Co-chaperone protein HscB homolog.
What is the protein family that this protein belongs to?
Belongs to the HscB family.
Protein: HEMA_I85A6
Sequence: MNTQILILTLVAAIHTNADKICLGHHAVSNGTKVNTLTERGVEVVNATETVERRTIPRICTKGKKAIDLGQCGLLGIITGPPQCDQFLEFTADLIIERREGNDVCYPGKFVNEEALRQILRESGGINKETTGFTYSGIRTNGVTSACRRSGSSFYAEMKWLLSNTDNAAFPQMTKSYKNTRNEPALIVWGIHHSGSATEQTKLYGSGNKLITVGSSNYQQSFVPSPGARPQVNGQSGRIDFHWLILNPNDTVTFSFNGAFVAPDRVSFFKGKSMGIQSEVPVDTNCEGECYHNGGTITSNLPFQNVNSRAVGKCPRYVKQKSLLLATGMKNVPEIPKKREKRGLFGAIAGFIENGWEGLVDGWYGFRHQNAQGEGTAADYKSTQSAIDQITGKLNRLIEKTNQQFELIDNEFTEVEKQIGNVINWTRDSITEVWSYNADLLVAMENQHTIDLTDSEMNKLYERVRRQLRENAEEDCTGCFEIFHKCDDDCMASIRNNTYDHSTYREEAMQNRVKIDPVKLSSGYKDVILWFSLGASCFLLLAIAMGLVFMCVKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: GSH1_PSEAB
Sequence: MSDLLSRRLALLGAAANLPLLTECLHGIERECLRVDSDGKLALTPHPRALGSTLTHPQITTDYSEALLEFITPTETDVADTLGDLERIHRFASSKLDGEYLWSPSMPCELPDEESIPIARYGSSLIGRLKYVYRKGLALRYGKTMQCIAGIHYNFSLPERLWPLLRQAEGSELSERDYQSAAYIALIRNFRRYSWLLMYLFGASPALDAGFLRGRPSQLERLDEHTLYLPYATSLRMSDLGYQNNAQAGLTPCYNDLQSYIDSLRQAVSTPYPPYEKVGTKQDGEWVQLNTNILQIENEYYSSIRPKRVTYTGERPVQALAARGVQYVEVRCLDINPFLPLGIDLDEARFLDAFLLFCAFSDSPLLNGECSDATDNFLAVVKEGRRPGLQLQRRGQPVELKVWANELLERIADTAALLDRARGGEAHAAALAAQRAKVADAELTPSAQVLKVMRERGESFEAFSLRQSREHAEYFRQHPLAAEEQARFEKMASDSLAEQTELERDQDGDFDTFVAAYQASILGLISN
What are the official names of this protein?
Glutamate--cysteine ligase, Gamma-ECS, GCS, Gamma-glutamylcysteine synthetase.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
Protein: RVE7_ARATH
Sequence: MLCFVRFQAGFVRIIVAARKRFRYFLMAAEDRSEELSSNVENGSCNSNEGINPETSSHWIENVVKVRKPYTVTKQREKWSEEEHDRFLEAIKLYGRGWRQIQEHIGTKTAVQIRSHAQKFFSKMAQEADSRSEGSVKAIVIPPPRPKRKPAHPYPRKSPVPYTQSPPPNLSAMEKGTKSPTSVLSSFGSEDQVNRCSSPNSCTSDIQSIGATSIDKKNNYTTSKQPFKDDSDIGSTPISSITLFGKIVLVAEESHKPSSYNDDDLKQMTCQENHYSGMLVDTNLSLGVWETFCTGSNAFGSVTEASENLEKSAEPISSSWKRLSSLEKQGSCNPVNASGFRPYKRCLSEREVTSSLTLVASDEKKSQRARIC
What is the function of this protein?
Transcription factor involved in phytochrome A-mediated cotyledon opening.  Controlled by the central oscillator mediated by LHY and CCA1.  Part of a regulatory circadian feedback loop.  Regulates its own expression.
What are the official names of this protein?
Protein REVEILLE 7, Early-phytochrome-responsive 1, MYB-related transcription factor EPR1.
What are the subcellular locations of this protein?
Nucleus.
Protein: GET1_PODAN
Sequence: MPSLLLIIFVTELVVQLVNTLGATTINDLLWRIYLTLPTPLSLEFAQQRRKQKEYLAVRHELKATSSQDEFAKWAKLRRQHDKLLEDLEKKKASLEAARTKFDRTLTTTRTVSTRSVQWFLPFWYSKEPMFWLPYGWFPYYVEWFASFPRAPMGSVSIVVWQWACTAVIALMIEAATAALVYVAAKQSQKIRQPVPAQSEKKDS
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein GET1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: MAZE5_MYCTO
Sequence: MKTARLQVTLRCAVDLINSSSDQCFARIEHVASDQADPRPGVWHSSGMNRIRLSTTVDAALLTSARDMRAGITDAALIDEALAALLARHRSAEVDASYAAYDKHPVDEPDEWGDLASWRRAAGDS
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Labile antitoxin that binds to its cognate MazF5 endoribonuclease toxin and neutralizes its activity.
What are the official names of this protein?
Antitoxin MazE5.
Protein: KYNB_BACCR
Sequence: MKTSEWIDISQPLNNNIATWPGDTPFSYEVSWSKEESGSVNVGKLTMSIHTGTHIDAPFHFDNDGKKVLDLDVQVYVGPARIIDVSNLESIGKKELESFHLEGVERLLLRTSSHGKAEEFPEVIPHLRADIASFLSEKGIRLIGVDVPSVDPLDDKELAAHHQLFKHGIHILENVVLDHVADGDYELIALPLALTDADGSPVRAVIRPI
What is the function of this protein?
Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
What are the official names of this protein?
Kynurenine formamidase, KFA, KFase, Arylformamidase, N-formylkynurenine formamidase, FKF.
What is the protein family that this protein belongs to?
Belongs to the Cyclase 1 superfamily. KynB family.
Protein: COAD1_ORYSJ
Sequence: MITPPVAGDTFAGAPPPPSQEEDAPPYGSVVLGGTFDRLHDGHRRLLKASADLARDRIVVGVCTGPMLAKKEYAELIEPVEKRMKAVEDYIKSVKPELVVQVEPIEDPYGPSIIDDKLDAIIVSKETLNGGFAVNRKREEKGLPLLKVEVVDLLSGGAEGEKLSSSALRKLEAEKANQQEGAASKGV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.  Does not accept 4'-phosphopantothenoylcysteine as a substrate (By similarity).
What are the official names of this protein?
Phosphopantetheine adenylyltransferase 1, Dephospho-CoA pyrophosphorylase 1, Pantetheine-phosphate adenylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic CoaD family.
Protein: RNPH_ACIB5
Sequence: MRIDQRALDQLREVKITRNYTRYAEGSVLVEFGHTKVLCTASIDNSVPRFLKGQGQGWVTAEYGMLPRSTHSRCDREAARGKQTGRTQEIQRLIGRSLRAMVDLKKLGENTITIDCDVIQADGGTRTASITGAAVALVDAMNVLLAQKKIKQDPLKGLVAAISVGMYQDEVLLDLCYEEDSNCQTDLNVVMTQAGEFIEIQGTAEDKPFTRAQSNAMLEMAEKGIAELIKKQQEALGW
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RL14_BRUAB
Sequence: MIQMQTNLDVADNSGARRVMCIKVLGGSKRRYASVGDIIVVSIKEAIPRGRVKKGEVMKAVVVRTAKDIRRPDGSVIRFDNNAAVLIDNKKEPIGTRIFGPVPRELRAKNHMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.