PharMolix/UniProtQA huggingface dataset:
Protein: OTC_MARN8
Sequence: MAARHFLTLNDMTTAELEDLLDHASKLRKEWRSGQTRDTLKNRVLAMIFEKSSTRTRVSFEAGMTQLGGSAMFLSPKDTQLGRGEPIEDSAIVISSMVDAVMIRTFAHETVERFATASSKPVINALTDEFHPCQLLADMQTYRELRGSIRGATVAWIGDGNNMCHSYINAAERFDFRLNVACPEGYEPDQQLIEQHADRVTVVRAPEEAARGAQLLVTDVWASMGQEDEQKAREKAFRSYQINPALMAQADKDALFMHCLPAHRGEEISADMMDHESSAVWHEAENRLHAQKALLEFLILNRLD
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LCP34_DROMI
Sequence: MFKILLVCALAALVAANENAEVKELVNEVNPDGFKTVVSLSDGSASQASGDVHGNIDGVFEWVSPEGVHVRVAYKADENGYQPSSDLLPVAPPIPEAILKSLAWIEAHPSKE
What is the function of this protein?
Component of the larval cuticle.
What are the official names of this protein?
Larval cuticle protein III/IV.
Protein: TATA_MYCBT
Sequence: MGSLSPWHWAILAVVVIVLFGAKKLPDAARSLGKSLRIFKSEVRELQNENKAEASIETPTPVQSQRVDPSAASGQDSTEARPA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NADD_MYCBO
Sequence: MGVMGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKDTLADLHALHPDSELYFTTGADALASIMSWQGWEELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISSTDCRQRAEQSRPLWYLMPDSVVQYVSKCRLYCGACDAGARSTTSLAAGNGL
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: STP2_ARATH
Sequence: MAVGSMNVEEGTKAFPAKLTGQVFLCCVIAAVGGLMFGYDIGISGGVTSMDTFLLDFFPHVYEKKHRVHENNYCKFDDQLLQLFTSSLYLAGIFASFISSYVSRAFGRKPTIMLASIFFLVGAILNLSAQELGMLIGGRILLGFGIGFGNQTVPLFISEIAPARYRGGLNVMFQFLITIGILAASYVNYLTSTLKNGWRYSLGGAAVPALILLIGSFFIHETPASLIERGKDEKGKQVLRKIRGIEDIELEFNEIKYATEVATKVKSPFKELFTKSENRPPLVCGTLLQFFQQFTGINVVMFYAPVLFQTMGSGDNASLISTVVTNGVNAIATVISLLVVDFAGRRCLLMEGALQMTATQMTIGGILLAHLKLVGPITGHAVPLIVLILICVYVSGFAWSWGPLGWLVPSEIYPLEVRNAGYFCAVAMNMVCTFIIGQFFLSALCRFRSLLFFFFGIMNIIMGLFVVFFLPETKGVPIEEMAEKRWKTHPRWKKYFKD
What is the function of this protein?
Mediates an active uptake of hexoses, probably by sugar/hydrogen symport.  Can transport glucose, 3-O-methylglucose, xylose, mannose, fructose and galactose.
What are the official names of this protein?
Sugar transport protein 2, Hexose transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPA49_MOUSE
Sequence: MATLESPGMDDQAGDTETEALQSARWLYCGEPDDRQKAVLVQFSNGKLQNPGDMRFTLYNSTDLVNPRQRSHRIVAAETDRLSYVGNNFGTGALKCNALCRHFVGILNKTSGQMEVYDAELFNMQPLFAGMGTEVIKLGGQHLYLLAFCQPSKNLAEAGDLLLSRHRQGHCIAVLLDDDAIEREPPLENQNKTFRDKLDSCIEAFGSTKQKRSLNSRRMNKVGSESLNLSVAKAAESIIDTKGVNALVSDAMQDDLQDGVLYLPPCYADAAKPEDVYRFEDILSPAEYDALESPSEAFRKVTSEDILKMIEENSHCSYVIEMLKSLPIDEVHRNRQARSIWFLDALIRFRAQKVIKGKRALGPGIPHIINTKLLKQFTCLTYNNGRLQNLISSSMRAKITSYAIILALHINNFQVDLTALQKDLKLSEKRMIEIAKAMRLKISKQKVSLADGREESHRLGTLSVPLPPAQNSDRQSKRRKMN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase I which synthesizes ribosomal RNA precursors (PubMed:8641287, PubMed:9254723).  Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF (PubMed:8641287).
What are the official names of this protein?
DNA-directed RNA polymerase I subunit RPA49, RNA polymerase I subunit A49, DNA-directed RNA polymerase I subunit E, RNA polymerase I-associated factor 1, RNA polymerase I-associated factor 53.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NU5M_MARPO
Sequence: MYLLIVILPLIGSFAAGFFGRFLGSRGVAVVTTTCVSLSSIFSCIAFYEVALCASACYIKIAPWIFSELFDAAWGFLFDSLTVILLLVVTIVSSLVHIYSISYMSEDPHSPRFFCYLSIFTFFMLMLVTGDNFIQLFLGWEGVGLASYLLINFWFTRIQANKAAIKAMLINRVGDFGLALGIMGCFTIFQTVDFSTIFACASAFSEPHHYFLFCNMGFHAITVICILVFIGAVGKSAQIGLHTWLPDAMEGPTPVSALIHAATMVTAGVFMIARCSPLFEYSPNALIVITFVGAMTSFFAATTGILQNDLKRVIAYSTCSQLGYMIFACGISNYSVSVFHLMNHACFKALLFLSAGSVIHAMSDEQDMRKMGGLASLLPFTYAMMLIGSLSLIGFPFLTGFYSKDVILELAYTKYTISGNFAFWLGSVSVFFTSYYSFRLLFLTFLAPTNSFKRDLSRCHDAPILMAIPLILLAFGSIFVGYLAKDMMIGLGTNFWANSLFILPKNEILAESEFATPTIIKLIPILFSTLGSFVAYSVNFVVNPLIFALKTSTFGNRLYCFFNKRWFFDKVFNDFLARSFLRFGYEVSFKALDKGAIEILGPYGISYTIRKMAQQISKIQSGFVYHYAFVMLLGLTIFISVIGLWDFISFWVDNRLYFIYIVSFLFINI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CLPX_SYNJA
Sequence: MAKHDSHLRCSFCNKSQDQVRKLIAGPGVYICDECVELCNEILEEELYDGNTPPATAPAASRRETPRKSSRSLPSLAQLPKPREIMRYLDQYVIGQEKAKKVLSVAVYNHYKRLAAKANPNSLGAAELDEVELQKSNILVIGPTGSGKTLLAETLARMLDVPFAVADATTLTEAGYVGEDVENILLRLLQVADMDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTIANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRIGKKSMGFIKPGEQLAVTREQRLADALKALEPEDLIKYGMIPEFIGRLPVVATLDPLDEKALEAILTQPKNAILKQAQKLLRMDGVELEFEPAAISAIAKEAYRRKTGARALRAIVEELMLDVMYEVPSRRDIKYVRITAEMVERRSTHELIPHPSTLPKPESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: PTH_TREDE
Sequence: MIDLIVFLGNYGKKYENTRHNAAWVLCDSIEIGSNAVWQSKFKGQYAKLPSSMTPGRAVHLLKPETYMNLSGESVIAAASFFRLKPENILIVHDELELKPGILSFKWSGGLGGHNGLRSIKSVLNTADFFRLRIGIGRPDFSSQGGDASPDISGYVLSRFAQSELDVLKSQVPQADSFFKELLEADEPQTLIKKWAKVLPSQS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBFA_STAA1
Sequence: MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDLSQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGNKIERMIQDLHKQDR
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1105L_ASFM2
Sequence: MLVIFLGILGLLANQVSSQLVGQLHPTENPSENELEYWCTYMECCQFCWDCQDGLCVNKLGNTTILENEYVHPCIVSRWLNKCMYDLGQGIDHVMVCSQPKYWNPYKILKKEWKENNSQN
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-5L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
Protein: VGL2A_DANRE
Sequence: METPREPAGFSKEGLKQLAGKTLGHVYRVIEKRQKPGENIELTEDGRPAQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKEKAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADPELTSDEKCGFIDEDELAEETGDITQSYGALGAPAKSYGATTQLNGGWAEGWDKREEYVQDGVEEGGYGYRQGGNYS
What is the function of this protein?
Multifunctional transporter that transports L-glutamate as well as multiple ions such as chloride, proton, potassium, sodium and phosphate.  At the synaptic vesicle membrane, mainly functions as a uniporter which transports preferentially L-glutamate but also, phosphate from the cytoplasm into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells.  The L-glutamate or phosphate uniporter activity is electrogenic and is driven by the proton electrochemical gradient, mainly by the electrical gradient established by the vacuolar H(+)-ATPase across the synaptic vesicle membrane.  In addition, functions as a chloride channel that allows a chloride permeation through the synaptic vesicle membrane therefore affects the proton electrochemical gradient and promotes synaptic vesicles acidification.  Moreover, functions as a vesicular K(+)/H(+) antiport allowing to maintain the electrical gradient and to decrease chemical gradient and therefore sustain vesicular L-glutamate uptake.  The vesicular H(+)/H(+) antiport activity is electroneutral.  At the plasma membrane, following exocytosis, functions as a symporter of Na(+) and phosphate from the extracellular space to the cytoplasm allowing synaptic phosphate homeostasis regulation.  The symporter activity is driven by an inside negative membrane potential and is electrogenic (By similarity).  Also involved in the regulation of retinal hyaloid vessel regression during postnatal development (By similarity).  May also play a role in the endocrine L-glutamatergic system of other tissues such as pineal gland and pancreas (By similarity).  Required for glutamate release by retinotectal synapses and visual acuity (PubMed:17196531).
What are the official names of this protein?
Vesicular glutamate transporter 2.1, Protein blumenkohl, Solute carrier family 17 member 6-B, Vesicular glutamate transporter 2-A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein. Synapse, synaptosome. Cell membrane; Multi-pass membrane protein.
Protein: TRPF_STAAM
Sequence: MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TBA1B_PIG
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:7225365).  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms (PubMed:7225365).  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:7225365).
What are the official names of this protein?
Tubulin alpha-1B chain, Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL5_YERP3
Sequence: MAKLHDYYKDEVVKQLMSQFGYDSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPFITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDDEGRALLAAFKFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ACDD2_METAC
Sequence: MAKKMKLSDITNMFAGMDVEALEGVTIEGDIEIDLGGLGGGFDPMLAAALGQESAILAQHFARLAGMFGYPVGIGAPAAPAVSPALAAPKLKDLIPAKFDVANIAEWATEIQEVPIGNTSADGGSRGKRVMLGGEKALPFYFDAPMPNRNQVTIDVFDMRIGLAKAVKENYDEVMDSPGEWAKKNVEKFNADMITIHLISTDPLIKDTPAKEAAKTVEEVLQAVDVPIAIGGSGNPQKDPEVLARAAEVSEGERCLLASASLNLDYAAIAEAALKYDHDVLSWTQLDMNAQKELNRKLMKQCNVPRDRIIMDPTTAALGYGLDYAYTNMERIRLAALMGDDELTFPMSSGTTNAWGARESWMVSSPLKEDSDWGPREYRGPIWEIVTGLSLAIAGNDLFMMMHPTSVAVLKQITQTLFGMIDTEQVDVANWIGAEV
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  Probably maintains the overall quaternary structure of the ACDS complex (By similarity).
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit delta 2, ACDS complex subunit delta 2, Corrinoid/iron-sulfur component small subunit 2.
What is the protein family that this protein belongs to?
Belongs to the CdhD family.
Protein: UPPP_ACIBY
Sequence: MENFEVIKALFLGFVEGLTEFLPISSTGHLILFGHIIDFHSDGGRVFEVVIQLGAILAVCWLYRQKIINLIKGFFSGDVESRHFAISVLIAFSPAVIIGVLAVDFIKSVLFSPIVVAIALIVGALIIFWVESKQFEHKTDDATKITFKQALLVGLAQCVAMIPGTSRSGATIVGGMFAGLSRKAATEFSFFLAMPTMLGAATFDLIKNADVLTSDNMVNIGVGFVAAFIAALLVVKALVLFVERHTLRVFAWYRIVLGVIILIAAMFFNLSA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GATA_DESDA
Sequence: MTDICSLSLTAVAQALQKKELSAVDVTTACLDRITATEPHLAALLYVNAENALARATTLDSEGPDAARPLWGVPVTLKDAFSTRGMPTTAGSRMLEGYTPFYDAFAVQKLHEAGAVILGKTNLDEFAMGSSTENSAFKVTRNPWNLNKVPGGSSGGSAASVTAGQCFASLGTDTGGSIRQPASFCGCVGLKPTYGRVSRYGVIAYGSSLDQVGPLTRSVEDCARVLTAIAGYDSRDNTCDPRPAEDYAATLSSRPLKGARLGIPREFYGQGLSDEVRAACEAAIQAARNQDAELVEVSLPHTDAAIATYYIIAMAEASSNLARFDGVRFGHRSADIKNLDDLYVHSRTEGFGPEVKRRIMLGAYVLSSGYYDAYYRKAAQVRRLIRDELLAALGQCDALLAPVSPVTARDLGGNTADPLQIYLMDAYTLSLNLAGLPGLSLPVGLGAKSGMPVGMQIIGKPFEETQVLALGHSLEQALPGIGRPAL
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: GL_HCMV3
Sequence: MCRRPDCGFSFSPGPVVLLWCCLLLPIVSSVAVSVAPTAAEKVPAECPELTRRCLLGEVFQGDKYESWLRPLVNVTGRDGPLSQLIRYRPVTPEAANSVLLDDAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA.  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans- Golgi where secondary envelopment occurs.
Protein: RL29_SULNB
Sequence: MNYIDLKDKSEAELLAMLKEKKLELFTLNAKQKTMQLTNTSELRVAKKDIARIQTALTAARAK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RS17_STAA3
Sequence: MSERNDRKVYVGKVVSDKMDKTITVLVETYKTHKLYGKRVKYSKKYKTHDENNSAKLGDIVKIQETRPLSATKRFRLVEIVEESVII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: CHED_TRIL1
Sequence: MSEQDGSPIRKYFLFPGATHVDAEECEITTVLGSCVAVCLWDQRHGGGGMNHFMLPLWNGEGLATPKYGSIAMERLLEQVLAIGARKEHLVAKVFGGANLLSTSSAACPIGERNIELAMTQLEEWRIAVVATDLGGRVGRKIIMNTMTGVVLLGRGKQQNQ
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: KA321_CENMA
Sequence: KCRECGNTSPSCYFSGNCVNGKCVCPA
What is the function of this protein?
Blocker of voltage-gated potassium channels (Ref. 1).  Inhibits voltage-gated potassium channels Kv1. 2/KCNA2 (Kd=0. 96 nM) and Kv1. 3/KCNA3 (Kd=1. 3 nM) (Ref. 1).  Does not inhibit Kv1. 1/KCNA1, Kv1. 5/KCNA5, Kv11. 1/KCNH2/ERG1, KCa1. 1/KCNMA1, KCa3. 1/KCNN4, NaV1. 5/SCN5A, NaV1. 4/SCN4A or HV1/HVCN1 (Ref. 1).  Strongly inhibits the expression of the activation markers interleukin-2 receptor and CD40 ligand/CD40LG in anti-CD3-activated CD4(+) TEM lymphocytes (Ref. 1).
What are the official names of this protein?
Potassium channel toxin alpha-KTx 32.1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Potassium channel inhibitor family.
Protein: PHS_MYCA9
Sequence: MALLTDDQINAALAGLPGWTREGDSLRRAVTFDAFLDGIDAVRRIAEHAESVDHHPDIDIRWRTVTFVLSTHSEGGITDKDLALAETIDTQIGR
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RH41_ARATH
Sequence: MNEEGCVPHNSDVVKQKSIDQRAPLSGEPKCVICSRYGEYICDETNDDVCSLECKQALLRRVDSARVFPATDECFYVRDPGSSSHDAQLLRRKLDIHVQGQGSAVPPPVLTFTSCGLPPKLLLNLETAGYDFPTPIQMQAIPAALTGKSLLASADTGSGKTASFLVPIISRCTTYHSEHPSDQRRNPLAMVLAPTRELCVQVEDQAKMLGKGLPFKTALVVGGDPMSGQLYRIQQGVELIIGTPGRVVDLLSKHTIELDNIMTFVLDEVDCMLQRGFRDQVMQIFQALSQPQVLLFSATISREVEKVGGSLAKEIILVSIGNPNKPNKAVNQLAIWVDAKQKKQKLFDILRSQNHFKPPAVVYVSSRVGADLLANAITVVTGVKALSIHGEKPMKERRDVMGSFLGGEVPVLVSTGVLGRGVDLLVVRQVIVFDMPSTIKEYIHVIGRASRMGEKGTAIVFVNEDDRNLFPDLVAALKSSGAAIPKELINLTSREMHNKKRRVGY
What are the official names of this protein?
DEAD-box ATP-dependent RNA helicase 41.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX59 subfamily.
Protein: SYS_PARDP
Sequence: MHDIRAIRENPAAFDAALALRNLPPVSPEILSLDADRRSRIAAAEAAQAEQNKASKEAGAAKGRGDEAEFQRLRALVTAKKDETARLQAEATALDAKLRELLLAVPNLPLDGVPPGKDEDDNVEIRRWGEPRAFDFAPREHFEIEGVRPGMDFETAAKLSGSRFVVLKGGVARVHRALAQFMLDLHTEEHGLAETWAPVLVLSEMMEGTGQLPKFGEDSYQTREGWWLIPTSEVTLTNTVNGDLVDHASLPRRMVAHSQCFRSEAGSAGRDTSGMLRQHQFEKVEMVSITDAESGVEEHARMTRCAEAVLERLGLPYRTIVLCGGDMGFGARITHDLEVWLPGQGKYREISSVSYCGDFQARRMNARYRPAGGGKPEFVHTLNGSGLAVGRTLIAVLENGQQADGSVKLPEVLHPYLGGRTRLGADGVLA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL_SALPA
Sequence: MKQTVYTASPESQQIHVWSLNHEGTLTLVQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHHGRFVFVGSYNAGNVSVTRLQDGLPVELVDVVEGLDGCHSANITPDNRTLWVPALKQERICLFTLSDDGHLVAQEPAEVNTVEGAGPRHMVFHPNRQYAYCVNELNSSVDVWQLKNPHGEIECVQTLDMMPADFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSVEGFQPTEAQPRGFNIDNSGKYLIAAGQKSHHIAVYEITGTQGLLTEKGRYAVGQGPMWVVVNAY
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.