PharMolix/UniProtQA huggingface dataset:
Protein: TOST1_CAEEL
Sequence: MTTAIQYQVIPLADREHSNKVASILENKYKTATNKRITLNERFGVLEKGYTIQATEPETVKNDSDVFFVVHDRNLNSKKEFVENYLAKNPIVNSPEKVFEEEDKENAPTKKAVLKPSSTDEKKLTSSDIYIQEITRSILQSV
What is the function of this protein?
Component of the tost-1 variant of the PETISCO complex which plays an essential role in embryogenesis (PubMed:31147388, PubMed:31216475).  Within the complex acts as an adapter which binds to the complex via erh-2 (PubMed:31147388).  Does not seem to play a role in the biogenesis of a class of 21 nucleotide PIWI-interacting RNAs (piRNAs) that possess a uracil residue at the 5'-end (also called 21U-RNAs) (PubMed:31147388).  May inhibit 21U-RNA accumulation (PubMed:31216475).  Required for chromosome segregation and cell division in early embryos (PubMed:31216475).
What are the official names of this protein?
Protein tost-1, Twenty one u antagonist 1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=During early embryogenesis, localizes to the nucleus at prophase of cell division, and remains in the cytosol at interphase in 2- and 4-cell embryos (PubMed:31216475). Mainly localizes to the germline cytoplasm (PubMed:31216475).
Protein: CAPP_LACH4
Sequence: MTVKKLENSSDVNVVTEEVKILTNLLNESTEQLIGKELFTKIQNLIKISADKNYQELEDQIASLDNREMIVVARYFATLPLLINISEDVELASKVNVLNNTNQDYLGKLNDTIDIVAQKKNAKEILEKVNVVPVLTAHPTQVQRKTVLELTDKIHKLLRNYREVKNGIITRVEWTEELRACIEILMQTDIIRSHKLKVSNEITNVLTYYPKSLIPAITKFTARYKELAKKHGLDIPDATPITMGMWIGGDRDGNPYVTADTLKLSATLQGQVIFEYYIKQINQLYRSISLSTSYMKPSTEVMHLSELSNDDSPFRTNEPYRRAFYYIESRLVRSEQKLLNITNQHSFLKERDLEHLDQIPAYEDAQEFKADLEVIKRSLEENRDQAVVKSYFTEILEAIDVFGFHLATIDMRQDSSVNEACVAELLKSAEICDHYSELSEKEKVSLLLNELNNDPRNLHTNNKPKSELLQKELKIYKTARDLKDRLGEDLIKQHIISHTESVSDMLEQAIMLKEYDLLDNQSARVQVVPLFETVEDLNNARDIIKEYLNLDIVKKWLVSQHNYQEVMLGYSDSNKDGGYLASCWNLYKAQKDLTAIGEELGIKITYMHGRGGTVGRGGGPSYEAITAQPFNSINDRIRMTEQGEIIQNKYGNKDAAYYNLEMLVSATVDRIASKQIVSEEYIADFRSSMDKIVTESNEIYKKLVFENPNFLDYFLQATPIKEISNLNIGSRPASRKKLSDFSSLRAIPWVFSWSQSRVMFPGWYGVGSAFKHFIDADKKNLQELQHMYQGWPFFHALLSNADMVLSKSNMEIAKQYAELCQDEKTKSVFDIIYQEWKLTKQIILQIEGHDDLLSDAPNLKNSLASRMPYFNILNYIQLEMIKRDREDEIKGVFQSIIPITINGVASGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: UNG_LACP7
Sequence: MSMIQNDWLDSIGEEFHKPYYKQLYDFVKEEYSQTTIYPLAENIFNAFHFTPLSKVKVLILGQDPYHNVNQAHGLSFSVLPEQKDIPPSLQNIYKELQSDLGCFIPNNGYLKKWADQGVLLLNTVLTVRAHQANSHQGRGWEQFTNAIIQAVNQQDRPIVYLLWGKPAQSKIPMLTNPKHLILKAPHPSPLSSYRGFFGSKHFSQTNEFFNANGLEPIDWQIENI
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE2_JANMA
Sequence: MIPGEMLVEPGDIELNVGRATATVKVANSGDRPIQVGSHFHFYETNPALKFDRAIGYGMRLNITAGTAVRFEPGQERTVELVALAGDRKVYGFNGKVMGALDKKEGK
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSZ21_ARATH
Sequence: MTRVYVGNLDPRVTERELEDEFKAFGVLRNVWVARRPPGYAFLEFDDERDALDAISALDRKNGWRVELSHKDKGGRGGGGGRRGGIEDSKCYECGELGHFARECRRGRGSVRRRSPSPRRRRSPDYGYARRSISPRGRRSPPRRRSVTPPRRGRSYSRSPPYRGSRRDSPRRRDSPYGRRSPYANGV
What is the function of this protein?
Probably involved in intron recognition and spliceosome assembly.
What are the official names of this protein?
Serine/arginine-rich splicing factor RSZ21, RS-containing zinc finger protein 21, At-RSZ21, At-RSZp21, AtRSZ21.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family. RSZ subfamily.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: SODM_ORYSJ
Sequence: MALRTLASRKTLAAAALPLAAAAAARGVTTVALPDLPYDYGALEPAISGEIMRLHHQKHHATYVANYNKALEQLDAAVAKGDAPAIVHLQSAIKFNGGGHVNHSIFWNNLKPISEGGGDPPHAKLGWAIDEDFGSFEALVKKMSAEGAALQGSGWVWLALDKEAKKLSVETTANQDPLVTKGANLVPLLGIDVWEHAYYLQYKNVRPDYLSNIWKVMNWKYAGEVYENATA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn], mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DAPD_SHEB9
Sequence: MEALRQRIEAAFEARADITPSTVDASVRDDVQNVINMLDKGEVRVAEKIDGQWHVHQWLKKAVLLSFRIFDNVVIDGAETKYFDKVPLKFAEYDEARFKAEAIRVVPSATVRKGSFIGKNTVLMPSYVNLGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVVVEEGSVISMGVYIGQSTRIYDRETGEVHYGRVPAGSVVVSGNLPSACGKYSLYAAIIVKKVDAKTRGKVGINELLRIVD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOHH_GIBZE
Sequence: MSPSADTPEISNSADSTVLSLKKSLCSEDSPLPIRFRALFSLKHVATTADDDATRVAAIEAIAAGFASPSALLKHELAYCLGQTGNTAAVKPLRQVLSDLKEDPMCRHEAAEALGALGWADNLDILREYRDRKEEDISIVETCEIAIERIEWENSAERQKEKLRPSDFASIDPAPPMPESDKEAEVEDLGRKLMDTNADLFSRYRAMFALRDLASPPDLPTATPAVLALAKGLSDSSALFRHEIAFVFGQLSHPASIPALTEALSNTNEASMVRHEAAEALGSLGEKDGVEDTLRKFLHDKEKVVRESCIVALDIAEYEKGEDAEYALIPESAGAAA
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIMK_SALCH
Sequence: MKIAILSRDGTLYSCKRLREAAMRRGHLVEILDPLSCYMNINPAASSIHYKGRRLPHFDAVIPRIGSAITFYGTAALRQFELLGSYPLNESVAITRARDKLRSLQLLARQGIDLPITGIAHSPDDTSDLIKMVGGAPLVVKLVEGTQGIGVVLAETRQAAESVIDAFRGLNAHILVQEYIAEAKGCDIRCLVVGNEVVAAIERCAKAGDFRSNLHRGGVASIATITPRERDIAIKAAQTLGLDVAGVDILRAARGPLVMEVNASPGLEGIEKTTGVDIAGRMIQWIERHATPEFCLKIGG
What is the function of this protein?
Is an L-glutamate ligase that catalyzes the ATP-dependent post-translational addition of glutamate residues to the C-terminus of ribosomal protein S6 (RpsF).  Is also able to catalyze the synthesis of poly-alpha-glutamate in vitro, via ATP hydrolysis from unprotected glutamate as substrate.  The number of glutamate residues added to either RpsF or to poly-alpha-glutamate changes with pH.
What are the official names of this protein?
Ribosomal protein S6--L-glutamate ligase, Poly-alpha-glutamate synthase, Ribosomal protein S6 modification protein.
What is the protein family that this protein belongs to?
Belongs to the RimK family.
Protein: CCSA_ORYSI
Sequence: MLFATLEHILTHISFSTISIVITIHLITLLVRELGGLRDSSEKGMIATFFCITGFLVSRWASSGHFPLSNLYESLIFLSWALYILHMIPKIQNSKNDLSTITTPSTILTQGFATSGLLTEMHQSTILVPALQSQWLMMHVSMMLLSYATLLCGSLLSAALLMIRFRKNLDFFSKKKKNVLLKTFFFNEIEYFYAKRSALKSTFFPLFPNYYKYQLIERLDSWSYRVISLGFTLLTIGILCGAVWANEAWGSYWNWDPKETWAFITWTIFAIYLHSRTNPNWKGTKSAFVASIGFLIIWICYFGINLLGIGLHSYGSFTLPI
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SAU21_ARATH
Sequence: MALVRSLLGAKKILSRSTASAAPKGFLAVYVGESQKKRYLVPLSYLSQPSFQALLSKSEEEFGFDHPMGGLTIPCPEDTFINVTSRLQ
What is the function of this protein?
Functions as positive effectors of cell expansion through modulation of auxin transport.
What are the official names of this protein?
Auxin-responsive protein SAUR21, Protein SMALL AUXIN UP RNA 21.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GCH4_THEAB
Sequence: MRDVQSERDERNVPLKHVGIKNLKYPVVVLDKKNKNQHTIAEINMYVDLPKDFRGTHMSRFLEVLNKFHLKIDPKNIKAILDDLKKTLKAQSASIEIMFPYFLQKKAPVTKIESYMEYKCGFKAYDTNEECEFYIVVEVPIQTLCPCSKEISKYNAHNQRALARIEVETSELIWFEDLIELAESSASVPLFTLLKRPDEKYVTEKAYENPKFVEDVARDIALSLKENKKIRWFKVEVESFESIHNHNAYACVNSDTMEV
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: AAMAT_AMAPH
Sequence: IWGIGCNPCVGDEVAALLTRGEA
What is the function of this protein?
Major toxin belonging to the bicyclic octapeptides amatoxins that acts by binding non-competitively to RNA polymerase II and greatly slowing the elongation of transcripts from target promoters (PubMed:4865716, PubMed:363352, PubMed:7642577, PubMed:8702941).
What are the official names of this protein?
Alpha-amanitin proprotein.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: CP089_DANRE
Sequence: MKSLKMLYPLFMLLVLSSKIDLSNQDVIDNILMSLSKGITYFDMQGSNINLDGVVGYIILQAQLREATRTWPHSDFLSLSQRAAAISMLKRLSKSLSTAASTLQETDPKYFKEFEPILDSSFWSLPGEWSSTDPSLVYTSVRAMECYDEHMSDKCMTFLLGTWKDNGTPCIVTKTCRDTMTQFGCPHYSLSHQLLYFMIGTMKGCSKMLKGDLRLSRVNITVGHYKRIFCSNMMKSNQDIFKNSLTGQMQDIFIENILLCGLVGFSDFYKLDWLQSILTWQDQEAGCFGKEEDISHIFEEFLDAPHKRVKRREKTLTDGCSSHMTGVAVSALGGFLNFYLSEQDITKRPII
What are the official names of this protein?
UPF0764 protein C16orf89 homolog.
What is the protein family that this protein belongs to?
Belongs to the UPF0764 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ERS1_YEAST
Sequence: MVSLDDILGIVYVTSWSISMYPPIITNWRHKSASAISMDFVMLNTAGYSYLVISIFLQLYCWKMTGDESDLGRPKLTQFDFWYCLHGCLMNVVLLTQVVAGARIWRFPGKGHRKMNPWYLRILLASLAIFSLLTVQFMYSNYWYDWHNSRTLAYCNNLFLLKISMSLIKYIPQVTHNSTRKSMDCFPIQGVFLDVTGGIASLLQLIWQLSNDQGFSLDTFVTNFGKVGLSMVTLIFNFIFIMQWFVYRSRGHDLASEYPL
What is the function of this protein?
Cystine/H(+) symporter that mediates export of cystine, the oxidized dimer of cysteine, from vacuoles/endodomes.
What are the official names of this protein?
Cystine transporter, ERD suppressor, Transmembrane protein ERS1.
What is the protein family that this protein belongs to?
Belongs to the cystinosin family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: RACA_BACC1
Sequence: MEYKTPFIAKKLGVSPKAVVRIAQQLNLTIEKNKYGHFIFTQDDLDQMLEYHLSQIEKSQNTHPTQKTSSNDVEELKTQVNTIVQNISSHDFEQLTAQLNTITRRLDRMEEQMQDKANDVVTYQLLQHRREMEEMLERIQKLEATLKKEEPIYITPDTKPIYEREKKPKRRKMIFSIFGL
What is the function of this protein?
Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore.  Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure.
What are the official names of this protein?
Chromosome-anchoring protein RacA.
What is the protein family that this protein belongs to?
Belongs to the RacA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to cell poles and nucleoid.
Protein: Y2537_YERPN
Sequence: MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
What are the official names of this protein?
UPF0319 protein YPN_2537.
What is the protein family that this protein belongs to?
Belongs to the UPF0319 family.
Protein: XYL1_SCHSH
Sequence: MSPSPIPAFKLNNGLEMPSIGFGCWKLDKSTAADQVYNAIKAGYRLFDGAEDYGNEQEVGEGVKRAIDEGIVTREEIFLTSKLWNNYHDPKNVETALNKTLKDLKVDYVDLFLIHFPIAFKFVPIEEKYPPGFYCGDGDNFVYEDVPILETWKALEKLVKAGKIRSIGVSNFPGALLLDLFRGATIKPAVLQVEHHPYLQQPKLIEYAQKVGITVTAYSSFGPQSFVEMNQGRALNTPTLFEHDVIKAIAAKHNKVPAEVLLRWSAQRGIAVIPKSNLPERLVQNRSFNDFELTKEDFEEISKLDINLRFNDPWDWDNIPIFV
What is the function of this protein?
Reduces D-xylose into xylitol.
What are the official names of this protein?
NAD(P)H-dependent D-xylose reductase, XR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
Protein: IF1_LEGPA
Sequence: MAKEDHIEMAGTVIDTLPNTMFRVELENGHIVTAHISGRMRKNYIRILTGDKVKVELTPYDLSKGRIIFRDKG
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMA_CAMJ8
Sequence: MSLENFGNFLTLDEKHSFIKKYFKEFYTKDFKLFASKDKHYRTRAELSFYHENDTLFYAMFDPKSKKKYIIEYLDFADEKICAFMPKLLEYLRQDNKLKEKLFGVEFLTTKQELSITLLYHKNIEDIKSNLENLSNILHINLIARSKGKKLIFKTENLRQTLNIQDRKIFYEFNNDCFIQPNTTINEKMITWVCEILNTQKRMDLLELYCGYGNFTLALAPFFFKVLATEISKSNINFALKNCKLNNTTNIHFARLSSEELSLAIKKEREFFRLKDIRLDDFNFSHVLVDPPRAGLDKSVIDLIKKYENIIYISCNPITLKENLKELSLTHRVEEFALFDQFVNTPHLECGVFLSKV
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: TUS_YERE8
Sequence: MNKYDLIERLNNRFTALEAGLQALHQQLEDLPLLAARVFSLPEIEKGTEHQPIMHIPVNATVGAAARDLAIQHYQRLFIHHQGQNVSSKAALRLPGVLCFSVTESQLATCQKSIQHINQLKTELEHIITVESGLPSEQRFEFVHTHLHGLITLNTYRTITPLINPSSVRFGWANKHIIKNVTREDVLAQLNKSLNAGRAVPPFSREQWVELISQEINDVQRLPEQARLKIKRPVKVQPIARVWYQEQQKQVQHPCPMPLIAFCQLQSAAELPKLGELTDYDANQIKHKYKPDAKPLQLLVPRLHLYLEI
What is the function of this protein?
Trans-acting protein required for termination of DNA replication.  Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks.  The termination efficiency will be affected by the affinity of this protein for the terminator sequence.
What are the official names of this protein?
DNA replication terminus site-binding protein, Ter-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Tus family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KTHY_GEOSL
Sequence: MGYFITFEGIEGCGKTTQIKRAAQSLREAGHRVVVTREPGGCPIADDIRAILLDAGNSAMVPTTELLLYAAARAQHVAEVIAPALAEGAVVLCDRFTDSTLVYQGFGRNLDRDLIARLNTLAAGQIRPDLTILLDCPVAVGLARAAARINSRQTNREERFERESLLFHERVREGFLSLAGGEPHRFAVIDGNDGVEATATAVADVLLNRVPRR
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DPO3A_ECOLI
Sequence: MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEEHFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEYFLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVVGLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKEIERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVMLFTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISLTDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDLRGLIGSEQVELEFD
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria (PubMed:2932432).  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase catalytic subunit (PubMed:2932432).  It is tethered to replicating DNA by the beta sliding clamp (dnaN), which confers extremely high processivity to the catalytic subunit, copying a 5. 4 kb genome in 11 seconds, a speed of at least 500 nucleotides/second at 30 degrees Celsius (PubMed:2413035).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_SHEWM
Sequence: MFDILMYLFENYVHSEVEFLVDEDELTQELTRAGFHQSEIIKALSWLENLAELQEGDKPYLCNHAQHSFRIYTQDEMDKLDVECRGFILFLEQIEVLNVVTREMVIDRIMELDESALILEDLKWVVLMVLFNAPGNESAYEQMEDLIFEQPDGRLHS
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: SPT5H_PONAB
Sequence: MSDSEDSNFSEEEDSERSSDGEEAEVEEERRSAAGSEKEEEPEEEEEEEEEEEYDEEEEEEDDDRPPKKPRHGGFILDEADVDDEYEDEDQWEDGAEDILEKAPNIDNVVLDEDRSGARRLQNLWRDQREEELGEYYMKKYAKSSVGETVYGGSDELSDDITQQQLLPGVKDPNLWTVKCKIGEERATAISLMRKFIAYQFTDTPLQIKSVVAPEHVKGYIYVEAYKQTHVKQAIEGVGNLRLGYWNQQMVPIKEMTDVLKVVKEVANLKPKSWVRLKRGIYKDDIAQVDYVEPSQNTISLKMIPRIDYDRIKARMSLKDWFAKRKKFKRPPQRLFDAEKIRSLGGDVASDGDFLIFEGNRYSRKGFLFKSFAMSAVITEGVKPTLSELEKFEDQPEGIDLEVVTESTGREREHNFQPGDNVEVCEGELINLQGKILSVDGNKITIMPKHEDLKDMLEFPAQELRKYFKMGDHVKVIAGRFEGDTGLIVRVEENFVILFSDLTMHELKVLPRDLQLCSETASGVDVGGQHEWGELVQLDPQTVGVIVRLERETFQVLNMYGKVVTVRHQAVTRKKDNRFAVALDSEQNNIHVKDIVKVIDGPHSGREGEIRHLFRSFAFLHCKKLVENGGMFVCKTRHLVLAGGSKPRDVTNFTVGGFAPMSPRISSPMHPSAGGQRGGFGSPGGGSGGMSRGRGRRDNELIGQTVRISQGPYKGYIGVVKDATESTARVELHSTCQTISVDRQRLTTVGSRRPGGMTSTYGRTPMYGSQTPMYGSGSRTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNTPSRAEEEYEYAFDDEPTPSPQAYGGTPNPQTPGYPDPSSPQVNPQYNPQTPGTPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNTHSPASYHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTPGSGIEQNSSDWVTTDIQVKVRDTYLDTQVVGQTGVIRSVTGGMCSVYLKDSEKVVSISSEHLEPITPTKNNKVKVILGEDREATGVLLSIDGEDGIVRMDPDEQLKILNLRFLGKLLEA
What is the function of this protein?
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II.  DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A.  DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter.  Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex.  DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II.  TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme.  Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT5, DRB sensitivity-inducing factor large subunit, DSIF large subunit.
What is the protein family that this protein belongs to?
Belongs to the SPT5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLIP3_ARATH
Sequence: MEGVFLKMSVVGVSPMIPVGPSSFICAIGGSVEEKSTAASLPRWVSLRRLRPLEFLRIGGKREEKGTVRDDDAVLLERRDRNRNENDNGNWVLKILEVGSIWKGKRQRSGGGGGGEEDEEEEVAEPKKKEDLCEECDFCRIDDDDEDEEKEKTVFEFSEMLSKIPVEDAQMFAKLSFLGNLAYSIPKIKPENLLKYQKLRFVTSSIEKRMSLKVEENNNGEEDEEKKKLINPAVAYRIAASAASRLFSHSKSVLPFGSSKRQDNEEASLLATADSVTAVVAAKEEVKQAVADDLKSNRSPPCEWFVCDDDKSGTRFFFIQGSDSLASWQANLLFEPVPFEDLDVLVHRGIYEAAKGIYEQMLPEVHAHLNSRGKNRAFLRFSGHSLGGSLSLLVNLMLLIRGQVPASSLLPVITFGSPCIMCGGDRLLQKLGLPKSHLLGISMHRDIVPRAFSCNYPNRAAKLLKALNGNFRNHPCLNNQNVLYSPMGKLLILQPSERFSPPHPLLPPGSGLYLLASKNTDETEKSLRAAKILFFNSPHPLEILSDRRSYGSEGKIKRNHDMSSYLKALRHVIRKELKQMKAERDQWLRKFFIINILFSGRDSLKLITRFVASRSSQLVIIFFLPIRLLIMSVYSVVFHHSQAHFSFFK
What is the function of this protein?
Sn-1-specific phospholipase A1 that catalyzes the initial step of oxylipins and jasmonate (JA) biosynthesis.  Hydrolyzes polyunsaturated acyl groups preferentially from chloroplastic phosphatidylglycerol (PG).  May function downstream of abscisic acid (ABA), and provide a link between ABA-mediated abiotic stress responses and oxylipin and JA signalings.  In vitro, possesses broad substrate specificity.  Can hydrolyze the galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG), the sulfolipid sulfoquinovosyldiacylglycerol (SQDG), and the phoshpolipids phosphatidylcholine (PC), and phosphatidylglycerol (PG).
What are the official names of this protein?
Phospholipase A1 PLIP3, chloroplastic, Galactolipase PLIP3, Protein PLASTID LIPASE 3.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Peripheral membrane protein.
Protein: RS14Z_SULNB
Sequence: MAKKSMIAKQQRKAKFSTQAYTRCNICGRPHSVYRDFGLCRVCLRKMANEGLIPGMRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: KGUA_PHOPR
Sequence: MSKGTLYIVSAPSGAGKSSLINALLETNPTYDMKVSVSHTTRGMRPGEENGVHYNFISVEEFTELTEQESFLEHAEVFGNYYGTSRPWIEDQLNKGIDVFLDIDWQGARQIRIQMPAAKSLFILPPSKEELERRLNARGQDSETIIARRMQEARSEISHYNEYDYVIVNDDFDAALMDFKAIIRAERLKQDKQTAKYNSMLNALLAEQ
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.