PharMolix/UniProtQA huggingface dataset:
Protein: UBIB_KLEP7
Sequence: MTPGELRRLYFIIHTFLSYGLDELIPKMRITLPLRIWRRMLFWMPNRHQDQPLGARLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDRVAPFEGKLAQQQIEKAMGGLPVETWFDDFSVEPLASASIAQVHTARLKENGKEVVIKVIRPDILPIIKADMKLIYRLARWVPRLLPDGRRLRPQEVVREYEKTLLDELNLLRESANAIQLRRNFEDSPMLYVPEVYPDYCSESMMVMERIYGIPVSDVEALEAQGTNMQLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPEDPQYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKDKAPFWIERMPEIPELVYQSLQQSKQLQTSVDTIVRDMRVRHVRQGQSRYLFGIGAVLLLSGTLLFIHRPEWGMMPGWLMAGGVVTWLIGWRKTH
What is the function of this protein?
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
What are the official names of this protein?
Probable protein kinase UbiB, Ubiquinone biosynthesis protein UbiB.
What is the protein family that this protein belongs to?
Belongs to the ABC1 family. UbiB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TXMG5_MACGS
Sequence: MKAPATTLILVMSLISVLWATPDLEEGDLLAELGDLIATDDEYPMKPEERGCKLTFWKCKNKKECCGWNACALGICMPR
What is the function of this protein?
Insect and vertebrate active toxin.  Binds to site 4 of mammalian voltage-gated sodium channels and shifts the activation voltage of the mammalian Nav1. 2a/SCN2A channel to more hyperpolarized voltages, whereas the insect channel, DmNav1 (para), is not affected.  Competes for binding at site 3 of the insect sodium channel.  Causes temporary paralysis when injected into lepidopteran larvae at 8. 6 nmol/g.  A low intracranial injection dose into mice causes lacrimation, closure of the eyes and sweating.  A high injection dose causes extensive lacrimation and death.
What are the official names of this protein?
Beta-hexatoxin-Mg1a, Beta-HXTX-Mg1a, Neurotoxin magi-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 15 family. 01 (magi-5) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y051_NPVAC
Sequence: MSKRVRERSVVSDETAKRIRQNEHCHAKNESFLGFCNLEEIDYYQCLKMQYVPDQKFDNDFILTVYRMANVVTKQVRPYNSIDEKHHYNTVRNVLILIKNARLVLSNSVKKQYYDDVLKLKKNTDLESYDPLITVFLQIGESVNEEIQKLRKALVNIFTNKPDKSDINNPDVVSYQFIFGRVQKLYNRAIKQKTKTIIVKRPTTMNRIQIDWKTLSEDEQKMTRQEIAEKIVKPCFEQFGTILHIYVCPLKHNRIIVEYANSESVQKAMTVNDDTRFTVTEFSVVQYYNVAKTEMVNQRIDIISKDIEDLRNALKSYT
What are the official names of this protein?
Uncharacterized 37.5 kDa protein in LEF8-FP intergenic region.
Protein: SELD_PASMU
Sequence: MNDTIASTVRLTQYSHGAGCGCKISPKVLEKILHSDMEKWVDPHLLVGNETKDDAAVYDIGNGIGIISTTDFFMPIVDDPFDFGRIAATNAISDIFAMGGKPIMAIAILGFPIKLLPPEVAQRIVDGGRFACRQAGITLAGGHSIDAPEPIFGLAVTGIINTDKVKKNASATAGCKLFLTKPLGIGVLTTAEKKGKLKAEHQGLATEVMCQMNTIGAKFAEIAGISAMTDVTGFGLLGHLSELCEGSGVRAEVYFDKIKTLDGVQRYIEKGCIPGGTERNFESYGHKIGAMSDLQKAILCDPQTSGGLLIAVDADSEQQVLEIAADDSIELFEVGRLFAKEHDSPILITVL
What is the function of this protein?
Synthesizes selenophosphate from selenide and ATP.
What are the official names of this protein?
Selenide, water dikinase, Selenium donor protein, Selenophosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein: BDLF2_EBVG
Sequence: MVDEQVAVEHGTVSHTISREEDGVVHERRVLASGERVEVFYKAPAPRPREGRASTFHDFTVPAAAAVPGPEPEPEPHPAMPIHANGGGETKTNTQDQNQNQTTRARTNAKAEERTAEMDDTMASSGGQRGAPISADLLSLSSLTGRMAAMAPSWMKSEVCGERMRFKEDVYDGEAETLAEPPRCFMLSFVFIYYCCYLAFLALLAFGFNPLFLPSFMPVGAKVLRGKGRDFGVPLSYGCPTNPFCKVYTLIPAVVINNVTYYPNNTDSLGGHGGFEAAALHVAALFESGCPNLQAVTNRNRTFNVTRASGRVERRLVQDMQRVLASAVVVMHHHCHYETYYVFDGVGPEFGTIPTPSFKDVLAFRPSLVTNCTAPLKTSVKGPNWSGAAGGMKRKQCRVDRLTDRSFPAYLEEVMYVMVQ
What is the function of this protein?
Rearranges cellular actin to increase intercellular contacts and thereby promote virus cell-to-cell spreading.  Induce the outgrowth of long, branched plasma membrane fronds to create intercellular network for virion traffic.  The fronds are actin based and RhoA-dependent (By similarity).
What are the official names of this protein?
Protein BDLF2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae BDLF2 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein.
Protein: END8_SHIF8
Sequence: MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKTYQSQLIGQHVTHVETRGKALLTHFPNGLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTILLYSASDIEMLRPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYATRGQVDENKHHGALFRFKVFHRDGELCERCGGIIEKTTLSSRPFYWCPGCQH
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine.  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Endonuclease 8, DNA glycosylase/AP lyase Nei, DNA-(apurinic or apyrimidinic site) lyase Nei, Endonuclease VIII.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: TMCAL_LISMO
Sequence: MKATGIVVEYNPFHNGHKLHLNKARELTQADVVIAVMSGSFVQRGEPAIIPKWERAKMALSAGVDMVVELPVSFATQHATIFAEEAVRILDAIHIDTLFFGSEHGVAEDFTFAAKKVVENEARFDEAIQLALVDKKTSYARAYTEAFKKLFGQNLLDITKPNNILGFHYALAVQKQNPSISLQTIPREHAGYHDEEASHDQIASATAIRKLILAGKLEEASHYLPASSIDILRNYEGPFLSWTDYWSFLQYRLIQASTEELEGIRGVSEGIQNRMQQAATKAQNFSDFIELTKTKRYSNARLQRTALQILLNAKSKASSPYIRILGMNKTGQKYLSLHKKNISLPIVTTVSKAPPGLLEEELRATNIYTLVKKLENYQAGDFHIPPILTL
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2755_YERPS
Sequence: MQIWVDADACPNVIKEVLFRAADRTGMMVTLVANQPLKTPPSKFIRTVQVASGFDVADNEIVQRVEKNDLVITADIPLAAEVIEKGGIALNPRGERYTPDTIRERLNMRDFMDTMRASGIQTGGPNTLNQRDRQQFANELDKWLQQARNQAK
What are the official names of this protein?
UPF0178 protein YPTB2755.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: PURA_DEIGD
Sequence: MPGIAIIGAQWGDEGKGKITDFLAPQADYVVRYQGGANAGHTVTAKGQTFKLNLLPSGVLHPGTVSILGDGMVIDPEKFLAERQNLLDGGLQPELRISDRAHLVLPHHKFVDGRKDFVGTTGRGIGPAYADRARRVGIRFGDLADESVLRERVERLLEAKPNSTRDAGWTSVTDALGYLLPIRDALLPFVGDTGAQLRQAIREGRNVLFEGAQATLLDLNYGTYPFVTSSHPTVGGILVGAGVNHKAINKVYGVAKAFNTRVGHGPFPTEVFGEMETRLRGDGSNPWDEFGTTTGRARRVGWLDLALLKYAVDVNGLDGLVINKMDILAGLDTVKVGVGYNAAGQPVYRELPGWATTAGAESRATLPKEAQAYLDLIEETVNCPVVIFSCGPAREQTYGAVSWD
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP09_MOUSE
Sequence: MPQFQTWEEFSRAAEKLYLADPMKVRVVLKYRHVDGNLCIKVTDDLVCLVYRTDQAQDVKKIEKFHSQLMRLMVAKESRNVTMETE
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP (By similarity).  The complex of SRP9 and SRP14 is required for SRP RNA binding (By similarity).
What are the official names of this protein?
Signal recognition particle 9 kDa protein, SRP9.
What is the protein family that this protein belongs to?
Belongs to the SRP9 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTR1_LEIMA
Sequence: MKKTVEDRSLEFLIRRRNDAELPPLASLSCKHLKQHHWRDAFDDEQAALREQLWAVKTQLDVIPAETYTATRNKLFPLAASGEQRNFSNRAGHKLLESMESTGVWMELSKLLRGKSTKRPRDFAFADVCGGPGAFSQALFQAGRKRGWRHLHGYGMTLAGVSGLDWYAHLLKSPQFTCTYGLDGTGDIFKLSNIDCLASITKAAPMFLVVADGGFNVDFSVTNYQETISSRIMYGQWLAALKLLRKGGCFVLKLFDTFSPLSRAVLYLSCCMYRRVHVAKPRHSRVVNSERYLVCVDFLGYPSEGWSRYLDSFYEVGFVDNEHVPQLIPREWCLQDAVFMADVRDMNTAVATNQVIALQMILDAAPAMTEELKAKTIEKKPAAGSDDGRTPPPDEGGDGE
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs.  Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
What are the official names of this protein?
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1, Cap1 2'O-ribose methyltransferase 1, MTr1.
Protein: ENO_META1
Sequence: MSKIVSINAYEVLDSRGNPTVKVELTTEKAYAEALVPSGASTGSKEALELRDKGTKYEKNWFGGKGVQTAVDNVNEIIFPALKGKDVTKQFEIDKLMIELDGTETKSKLGANAILAVSLAVAKAAANEANVPLYAYLAKLDNRQAYKLPVPMLNVINGGEHASNTIDFQEFMIMPLGAKTFKEAMQIANFVFHTLAKLLKEAGHGTQVGDEGGFAPNLHTHEETLDFLVNAIKKAGYNPATSGDNAVAICLDTASSELYCSESKTYTFKKFKKALDEKRPGFEKYASMKYKFTSDEYVEYYGNLIAKYPIISIEDSHDENDWEGFRKMKKLYGNRVQLVGDDLIVTNPKYIKMAIEKDAINASLIKINQIGSLWETIEAIKMTQAANMVPVISHRSGETEDTFIADLAVAFNTGEIKTGSLSRTDRIAKYNRLLKIEQELGNKAKYEGRASFSNLK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: FGL1_RAT
Sequence: MGEIRSFVLITVALILGKESWVLGDENCLQEQVRLRAQVRQLETRVKQQQVVIAQLLHEKEVQFLDRGQEDSFIDLGGKRHYADCSEIYNDGFKHSGFYKIKPLQSLAEFSVYCDMSDGGGWTVIQRRSDGSENFNRGWNDYENGFGNFVQSNGEYWLGNKNINLLTMQGDYTLKIDLTDFEKNSRFAQYEKFKVGDEKSFYELNIGEYSGTAGDSLSGTFHPEVQWWASHQTMKFSTRDRDNDNYNGNCAEEEQSGWWFNRCHSANLNGVYYQGPYRAETDNGVVWYTWRGWWYSLKSVVMKIRPSDFIPNIV
What is the function of this protein?
Immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3.  Responsible for LAG3 T-cell inhibitory function.  Binds LAG3 independently from MHC class II (MHC-II).  Secreted by, and promotes growth of, hepatocytes.
What are the official names of this protein?
Fibrinogen-like protein 1.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in the blood plasma.
Protein: RS4_NOSP7
Sequence: MSRYRGPRLRIVRRLGDLPGLTRKSARRAYPPGQHGQNRKKRSEYAIRLEEKQKLRFNYGLTEKQLLRYVRKARRVTGSTGQVLLQLLEMRLDNTVFRLGIAPTIPAARQLVNHGHVTVNGRVVNIASYQCRPGEVIAVRDRAQSRKLVEANLQYPGLANLPSHLEFDKNKLVGKVNSVIEREWVALQVNELLVVEYYSRQA
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: FTSZ_ECOLI
Sequence: MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNTDAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAAGMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSLITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMSEMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFETVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQPVMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.  Polymerization and bundle formation is enhanced by CbeA.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles in a ring-like structure at midcell at the inner surface of the cytoplasmic membrane.
Protein: SYY_PYRHO
Sequence: MDIEERINLVLKKPTEEVLTVENLRHLFEIGAPLQHYIGFEISGYIHLGTGLMAGAKIADFQKAGIKTRVFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFVLASEILEKGDYWQTVIDISKNVTLSRVMRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQGVTIAHAGMDQRKAHVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIESEEEFKEIKAQMKMSKSKPYSAVFIHDSPEEIRQKLRKAFCPAREVRYNPVLDWVEYIIFREEPTEFTVHRPAKFGGDVTYTTFEELKRDFAEGKLHPLDLKNAVAEYLINLLEPIRRYFEKHPEPLELMRSVKITR
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_BARBK
Sequence: MYNYLDFEKPVADLDVQILELKKIAQEKGSLDMSDEIARLEMRSQTALRDLYKKLSPWQKTQVARHPDRPHFMDYSAQLLRDVTPLAGDRKFAEDEAIQAGFARFKGEAIAYIGQEKGHDTQTRLRYNFGSARPEGYRKAVRIMELADRFGLPLLTFVDTAGAYPGVSAEERGQAEAIAQSTAATLRLRVPVVSVIIGEGGSGGAIAIAAANKVYMLEHSIYSVISPEGAASILWRDPARAKDAATNMQITAQDLYRLKIIDGIIPEPLGGAHRQKEAAIEAAGDGIAAALKSMIGKDGETIKQERWDKYLQIGRSLA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_LISMF
Sequence: MEIRERILADMQVAETIDAHEEIRKSVEFLKAYLKKNTFLKSFVLGISGGQDSTLTGKLAQMAISEMRAETGDDEYQFFAVSLPYGTQLDESDRQDALNFMEPDNRLTVNIKASVDASVAALAEAGVELSDFAKGNEKARERMKVQYAIAAMHKGVVVGTDHSAEAVTGFYTKYGDGGTDINPLFRLNKRQGKALLKELGCPEHLYLKKPTADLEDNKPALPDEVALGVTYDQIDDYLEGKEVPADAAAKIENWFIKTEHKRHMAITIFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: YPBS_BACSU
Sequence: MSEVHKAISAHSSKQHEHIKAFMRLENMRELAIEEAVAKCRNDEPYTTDAINEITEQMNQLAKKGIVPTRRLVSKEMVREYVSRM
What are the official names of this protein?
Uncharacterized protein YpbS.
Protein: 3L2B_LATCO
Sequence: RICYLAPRDTQICAPGQEICYLKSWDDGTGSIRGNRLEFGCAATCPTVKRGIHIKCCSTDKCNPHPKLA
What is the function of this protein?
Binds with high affinity to muscular nicotinic acetylcholine receptors (nAChRs), whereas it binds with a low affinity to neuronal alpha-7/CHRNA7 nAChRs.
What are the official names of this protein?
Toxin Lc b.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SYDND_ELUMP
Sequence: MMRTNYCGDINKNYVNSVQVLCGWVNSYRDHGGVLFLDLRDRTGKVQVVVEPTNKDFELASTARTEYVLKVTGLVRLRQTEHINPNNPTGEIEVVAQEVEILNTSIQLPFEPDNSRQINEETRLKYRYIDLRNPVMLHNLTTRHKVAQAARRYFSDNGFIEIETPILTRSTPEGARDYLVPSRVHEGKFYALPQSPQMFKQTLMASGVDRYFQIARAFRDEDLRSDRQPEHTQIDIEMSFVTLADVFAAGEGMIAEVFKAAGEDAPAAPFEQMEYADVMAKYGSDKPDIRYEIDITDIGGIFTNSNFKVVSDALANGGVVRAIKAKYGAKHINRSTCDKLTDLAKASGAKGLVWLKYSDDKFEGPSAKFFTEEELASLQHTLSVEKDDMVFIGADKEKVVSPVMGAIRKELIKLLCLKPNKKWAFLWVKHFPLLEFVPEENRWDAAHNPFTAPLEKDIPLLDTDPGKVKSYQFDLVLNGVELASGSIRNHRRDLQEKILNLMKHSPEQAALRFGMLLNALEAGAPPHGGFGMGLDRLAALLCKEESIREVIAFPKTATAYCPLTESPNVVEDIQLKELHIKIK
What is the function of this protein?
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn).  Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
What are the official names of this protein?
Aspartate--tRNA(Asp/Asn) ligase, Aspartyl-tRNA synthetase, AspRS, Non-discriminating aspartyl-tRNA synthetase, ND-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLD2_HUMAN
Sequence: MTATPESLFPTGDELDSSQLQMESDEVDTLKEGEDPADRMHPFLAIYELQSLKVHPLVFAPGVPVTAQVVGTERYTSGSKVGTCTLYSVRLTHGDFSWTTKKKYRHFQELHRDLLRHKVLMSLLPLARFAVAYSPARDAGNREMPSLPRAGPEGSTRHAASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGRKGLEGMIRKRSGGHRVPGLTCCGRDQVCYRWSKRWLVVKDSFLLYMCLETGAISFVQLFDPGFEVQVGKRSTEARHGVRIDTSHRSLILKCSSYRQARWWAQEITELAQGPGRDFLQLHRHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAQEEIFITDWWLSPEVYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRALMLLHPNIKVMRHPDQVTLWAHHEKLLVVDQVVAFLGGLDLAYGRWDDLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGLPARDLARHFIQRWNFTKTTKAKYKTPTYPYLLPKSTSTANQLPFTLPGGQCTTVQVLRSVDRWSAGTLENSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHKQGWCYRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYISICGLRTHGELGGHPVSELIYIHSKVLIADDRTVIIGSANINDRSLLGKRDSELAVLIEDTETEPSLMNGAEYQAGRFALSLRKHCFGVILGANTRPDLDLRDPICDDFFQLWQDMAESNANIYEQIFRCLPSNATRSLRTLREYVAVEPLATVSPPLARSELTQVQGHLVHFPLKFLEDESLLPPLGSKEGMIPLEVWT
What is the function of this protein?
Function as phospholipase selective for phosphatidylcholine (PubMed:9582313).  May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity).
What are the official names of this protein?
Phospholipase D2, PLD 2, hPLD2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family.
Protein: RL21_SALTY
Sequence: MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETIEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CTLA4_PIG
Sequence: MACSGFQSHGAWLELTSRTWPCTALFSLLFIPVFSKGMHVAQPAVVLANSRGVASFVCEYGSAGKAAEVRVTVLRRAGSQMTEVCAATYTVEDELTFLDDSTCTGTSTENKVNLTIQGLRAVDTGLYICKVELLYPPPYYVGMGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLITAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
What is the function of this protein?
Inhibitory receptor acting as a major negative regulator of T-cell responses.  The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
What are the official names of this protein?
Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Note=Exists primarily an intracellular antigen whose surface expression is tightly regulated by restricted trafficking to the cell surface and rapid internalization.
Protein: Y262_GEOMG
Sequence: METVLNSCEIRVLGCLVEKELATPEYYPLTLNALTAACNQKSNRDPVMALEDADVVRALDSLRMKGFARQSAEGVRAMKYCHCLAEKFLLEPPDLAVLAELLVRGPQTVGELRTRAERMRPFADLAAVEEVLRMLMEREEPLVTRLPRQPGRKEQRYAHLLAGAPEAEGEESMAPPEGARLQVRAENERVARLEEEVTALRAEVAELRRMMEEFRSQFE
What are the official names of this protein?
UPF0502 protein Gmet_0262.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: RL11_PORGI
Sequence: MAKEVAGQIKLQIKGGAANPSPPVGPALGAKGINIMEFCKQFNARTQDKAGKVLPVVITYYADKSFDFIVKTPPVAIQLLEASKQKSGSAEPNRKKVAEITWEQVRTIAEDKLVDLNCFDIKAAMKMVAGTARSMGIAIKGDFPE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: BPI_RAT
Sequence: MAWGPDNVRKWSSLALLAIVGTALTAATDPGFVARISQKGLDFVCQESMVELQKELLAISIPDFSGDFKIKHLGKGTYEFYSMAVEGFHIPDPQIKLLPSDGLQLSITSASIKISGRWKYRKNILKASGNFQLSIQGVSIIADLILGNDPSGRITITCSTCDSHINSVRIKVSGSMLGWLIQLFHRKIETSLKKTIYKKICKIVRNSVSAKLQPYVKTLPVVAKVDDITSIDYSLLAPPMTTDKFLEGQLRGEFFWRGHHGPFPAVPPVMNILPNNNYMVCMGISDYFFNTAEFAYQESETLKITLRDQLLAKDARYHLNTDFLKTFLPEVAKKFPSMGLQLLISAPLFAHLNIQPSGLSLSPNLETRAFVVLPNSSLIPLFLLGMKTNASLEVNAMKNRLIGEMKLGRLLLELKQSNFGSFKVELLEDVINYLMSTMVLPKINEKLRRGFPLPLPAGIQLINSILYSSQNFLLLEADLHRT
What is the function of this protein?
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.
What are the official names of this protein?
Bactericidal permeability-increasing protein, BPI.
What is the protein family that this protein belongs to?
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic granule membrane. Note=Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Protein: ATPD_BRUA2
Sequence: MAETSSLISGVAQRYAGSLFEHALDANSVASVEKDLGRFEALLSGSEDLRRLISSPVFSSEDQLHAIGAIADKAGIKGLVGNFLRVVAQNRRLFALPGIIAAFRQIAAEHRGEISADVVSAHELTSAQQNELKATLKGVAGKDVTINVTVDPSILGGLIVKMGSRQIDTSLRTKLSSLKLALKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LTAA_STAAN
Sequence: MQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHIVWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNDLNNTFYFSALIFLVLAVFYGSYFIANREKAK
What is the function of this protein?
Proton-coupled antiporter flippase that catalyzes the translocation, from the inner to the outer leaflet of the cell membrane, of the lipid-linked disaccharide (anchor-LLD) that anchors lipoteichoic acids (LTA) to the cell membrane.
What are the official names of this protein?
Proton-coupled antiporter flippase LtaA, Lipoteichoic acid protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. LtaA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.