PharMolix/UniProtQA huggingface dataset:
Protein: CORC_ECO57
Sequence: MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRSQRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE
What is the function of this protein?
Plays a role in the transport of magnesium and cobalt ions.
What are the official names of this protein?
Magnesium and cobalt efflux protein CorC.
What is the protein family that this protein belongs to?
Belongs to the UPF0053 family.
Protein: DEOC_AERHH
Sequence: MTDLKLAAQRALNLMDLTTLNDDDTDQKVIDLCRKAKSPAGLTAAVCIYPRFIPIARKTLREIGAADVRIATVTNFPHGNDDIEIAVAETRAAVAYGADEVDVVFPYRAFMAGNEQVGFDLVKACKEACGSQALLKVIIETGELKEEALIRRASEISIDAGADFIKTSTGKVPVNATPEAARIMMEVIKAKNPKVGFKPAGGVKDAAVAGQYLAMAEEILGKDWVSARTFRFGASSLLASLLATLGHGDKPANTSGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACR_STAAN
Sequence: MNKHERLDEIAKLVNKKGTIRTNEIVEGLNVSDMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRYIARKAASLIEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMRHITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYLLIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD
What is the function of this protein?
Repressor of the lactose catabolism operon.  Galactose-6-phosphate is the inducer (By similarity).
What are the official names of this protein?
Lactose phosphotransferase system repressor.
Protein: I1B1_CONXI
Sequence: MMKLSVSFLLLLMLLPFITGEENSDSDVLKSGAAVRQGRGRCRGFREDCSQHRDCCGDLCCNGNTCVITVIACPKW
What is the function of this protein?
Antimicrobial peptide that potently inhibits growth of Mycobacterium tuberculosis (H37Rv strain) (MIC=3 uM).
What are the official names of this protein?
Conopeptide X11.1, I1_xm11a.
What is the protein family that this protein belongs to?
Belongs to the conotoxin I1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GL115_ARATH
Sequence: MKVSMSLILITFWALVTIAKAYDPSPLQDFCVAIDDPKNGVFVNGKFCKDPKQAKAEDFFSSGLNQAGITNNKVKSNVTTVNVDQIPGLNTLGISLVRIDYAPYGQNPPHTHPRATEILVLVEGTLYVGFVSSNQDNNRLFAKVLNPGDVFVFPIGMIHFQVNIGKTPAVAFAGLSSQNAGVITIADTVFGSTPPINPDILAQAFQLDVNVVKDLEAKFKN
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 1 member 15.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: ATPD_SYNY3
Sequence: MKGSLYSSKIAEPYAQALIGLAQQQNLTEVFGDNLRSLLTLLQDSPDLSAVLSSPVVKDEDKKSVLRSVLGDGGNGYLLNFLMLLVDKRRIVFLEAICEQYLALLRQFTNTVLAEVTSALKLTDAQKDQVKERVKQLTGAQAVELETKVDGDILGGIVIKVGSQVFDSSLRGQLRRVGLSLGTAL
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: DXR_ACIB3
Sequence: MTQSVCILGVTGSIGRSTLKILGQHPDKYSVFAVSAHSRISELVEICKQFRPKVVVVPEQKIAELKTLFAQQNISDIDVLAGQEGLVDIASHTDVDIVMAAIVGAAGLLPTLAAVKAGKRVLLANKEALVMSGEIMMQAARDHQALLLPVDSEHNAIFQSLPHNYLQADRTGQPQLGVSKILLTASGGPFLNHSLEQLVHVTPQQACKHPNWSMGQKISVDSATLMNKGLELIEACHLFSISEHFVTVVVHPQSIIHSMVQYVDGSTLAQMGNPDMCTPIAHALAWPERLQTNVPALDLFEYSQLNFQAPDTQKFPALNLARQAMRAGGLAPTILNAANEIAVEAFLMERIGFTSIPQVVEHTLEKLENAAAESIECILDKDKVARSVAQQYISSIGG
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CWLT_BACSU
Sequence: MISKKVVLPLVFSAPFIFFFVLCIVVVMTISRENQVGDDFIGGGDGEYETVGIAPEVERFRAVFEKYARQEGVFDQVNIIMALTMQESGGRSLDIMQSSESIGLPPNSITDPERSIEVGIKHFKKVFKQAGGDVRLTLQAYNFGSGFIDYVKKNGGKYTKKLALDFSRLQAFKMGWKSYGDPSYVDHVMRYVKGSDKNVKPVKGSMDFYETVMKEALKYEGQPYAWGGSNPETGFDCSGLVQWSFAKAGITLPRTAQEQHGATKKISEKEATAGDLVFFGGTYEGKAITHVGIYVGNGRMFNSNDSGIQYSDLKSGYWRDHLVSFGRIK
What is the function of this protein?
Exhibits both muramidase and DL-endopeptidase activities (PubMed:18305117, PubMed:24532767).  The N-terminal region acts as a N-acetylmuramidase, which cleaves the bond between N-acetylmuramic acid and N-acetyl-D-glucosamine (MurNAc-GlcNAc) in peptidoglycan (PubMed:18305117).  The C-terminal region acts as a DL-endopeptidase that cleaves the bond between D-gamma-glutamate and meso-diaminopimelic acid (PubMed:18305117).  Cannot degrade purified B. anthracis peptidoglycan, which differ from those of B. subtilis (PubMed:24532767).  CwlT is required for ICEBs1 conjugation: the muramidase activity is essential, whereas the peptidase activity is partially dispensable for transfer of ICEBs1 (PubMed:24532767).
What are the official names of this protein?
Bifunctional muramidase/DL-endopeptidase CwlT, Bifunctional cell wall hydrolase CwlT, Cell wall lytic enzyme T.
What is the protein family that this protein belongs to?
Belongs to the peptidase C40 family.
Protein: RS27A_HALSA
Sequence: MARGDYYSDDGTTDKEMCPRCGDTFLAAHDDRQVCGRCGYTEWE
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: RS21_BACC2
Sequence: MSKTVVRKNESLEDALRRFKRSVSKTGTLAEARKREFYEKPSVKRKKKSEAARKRKF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RL24_XYLF2
Sequence: MASRIKKGDQVIVIAGKDKGKQGEIIRIDGHRVVVSNVNFVKRHTKPNPQRGISGGLIDREAPIHVSNIKILNPMTGKGDRVGFKILGDGCKLRIFRSTGEVIGA
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: EFP_MYCLB
Sequence: MATTADFKNGLVLVIDGQLWTIIGFQHVKPGKGPAFVRTKLKNVLSGKVVDKTYNAGVKVDTATVDRRDTTYLYRDGANFVFMDSQDYEQHPLPESLVGDTARFLLEGMSVQVAFHNGVPLYVELPVTVELEVTHTEPGLQGDRSSAGTKPATLETGAQINVPLFINTGDKLKVDSRDGSYLGRVNV
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZIPA_ENT38
Sequence: MMQDLRLILIIVGAIAILALLVHGFWTSRKERSSMFRDRPLKRMKSSRNDDGDDDIEDNDDEGVGEVRVHRVNTAPGVGHGEQEAPRQSAQHQYQPPYASAQPRPQAPQPVEEPVRQPQTQPVHQQPVAQPQPVQQHQPVQPVQQPQPEPQTVQTQPAPPVEPEPVVEEAPVVEKPQRKETVIIMNVAAHHGTQLNGELLLNSIQQAGFKFGDMNIFHRHLSPDGSGPALFSLANMVNPGTFDPEMTGDFLTPGITIFMQVPSYGDELQNFKLMLQSAQHIADEVGGMVLDDQRRMMTPQKLREYQDRIREVKEANA
What is the function of this protein?
Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring.  Also required for the recruitment to the septal ring of downstream cell division proteins.
What are the official names of this protein?
Cell division protein ZipA.
What is the protein family that this protein belongs to?
Belongs to the ZipA family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type I membrane protein. Note=Localizes to the Z ring in an FtsZ-dependent manner.
Protein: PURA_BARHE
Sequence: MANVVVVGTQWGDEGKGKIVDWLSERADIIVRYQGGHNAGHTLVVNGVNYKLSLLPSGLVRGKLSIIGNGVVVDPHHFVVELKKLRDQGVKIVPEILRIAENAPLILSLHRDLDAIRESGFSGLKIGTTKRGIGPAYEDKVGRRAIRVMDLAEANTLMAKIKRLLRHHNALRRGMGVAEIDSQALYDELMQVADEILPFMDCTWRLLDESYRMGKHVLFEGAQGALLDNDFGTYPYVTSSNTVAGQACTGSGMGPGAIHYVLGIAKAYTTRVGEGPFPTEQINDIGEFLGIRGHEFGVVTGRKRRCGWFDAVLVRQMVTICGVQGIALTKLDVLDGLDEIKVCVGYELDGKRIDYLPSSMGAQSRVKPIYETLEGWKQATAHALKWEDLPVQAIKYIRYIEELIGTQVALLSTSPEREDTILITDPFAN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AN13C_XENTR
Sequence: MTGEKIRSLHRDQKPSKDEDLLEPDEEATAGGTFTRTGKLKNSKMFSNHKVIRSPSNPALLQNHHQQISPITPGESKTDAYFPVHECVFKGDIRRLSSLIRSHSIGQKDNHGNTPLHLAVMLGNKECAHLLLAHNAPVKVKNAQGWSPLAEAISYGDRQMITALLRKLKQQSRESVEEKRPRLLKALKELGDFYLELHWDFQSWVPLLSRILPSDACKIYKQGINIRLDTTLIDFTDMKCQRGDLSFIFNGDAAPSESFVVLDNEQKVYQRIHHEESEMETEEEVDILMSSDIYSATLSTKSISFTRAQTGWLFREDKTERVGNFLADFHLVNGLILESRKRREHLTEEDILRNKAIMESLSKGGNLMEQNFEPVRRQSLTPPPPNTITWEEYISAENGKAPHLGRELVCKENKKTFKATIAMSQDFPLGIESLLNVLEVIAPFKHFNKLREFVQMKLPPGFPVKLDIPVFPTITATVTFQEFRYGEFEDAIFTIPDDYKEDPSRFPDL
What is the function of this protein?
Acts as a molecular chaperone for G protein-coupled receptors, regulating their biogenesis and exit from the ER.
What are the official names of this protein?
Ankyrin repeat domain-containing protein 13C.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane. Note=Associated with the cytosolic side.
Protein: SKG1_CANGA
Sequence: MTGTVSTAVGCAVGIPVGVGVIVACLFWIRMQRRLKEEDIIDQELNRAVYDESGFVSFNNIDTLKAEPNGHPSSEDTNEVMHSSDIDDNGDDDDEDHNARRNNTYAAQDKNNGKYVPAYRRQINKHNSILQQQRKSRNLVNTMGHSIESLSMDDHSQANGKSRQVSVYDQMVPVLDDANRDSSSPFPTNDKDTSDKKSNLFQSHDVSANTSTSFFETRSNDNLIKNLNSHDFGSYYPRRPSTSNLNHSQGSLHTRNSSMLSLGKIENAENVFATPKSENILKHPHPLEHESSSISNETNNVTDNTIDGESASKSSKTYQLKNNYDIQNTSEIAEEDQYENEFTNYSENKRAYIDGLRPKM
What is the function of this protein?
Plays a role in cell wall integrity.  Affects the cell wall polymer composition in the growing region of the cell (By similarity).
What are the official names of this protein?
Suppressor of lethality of KEX2 GAS1 double null mutant protein 1.
What is the protein family that this protein belongs to?
Belongs to the SKG1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type III membrane protein; Cytoplasmic side. Bud membrane; Single-pass type III membrane protein; Cytoplasmic side. Note=Localizes on the inner surface of the plasma membrane at the bud and in the daughter cell. Localizes at an incipient bud site in the cells with emerging buds, a bud tip in small- or medium-budded cells, and a cell periphery in large-budded cells.
Protein: FGF16_DANRE
Sequence: MAEVAGFLGSIDLDLQAFPALGNVPLSDGLNERLGLIEGRLQRGSLTDFGHLKGILRRRQLYCRTGFQLEIFPNGTVHGTRQDHSRFGILEFISLAVGLVSIRGVDAGLYLGMNEKGELYGSKKLTAECVFREQFEENWYNTYASTLFKHADTGRYYYVALNKDGSPREGSRTKKHQKLTHFLPRPVEIEKIPQAYRELFQHR
What is the function of this protein?
Plays a crucial role in pectoral fin bud outgrowth.
What are the official names of this protein?
Fibroblast growth factor 16, FGF16.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Secreted.
Protein: KRT36_MOUSE
Sequence: MATQICTPTFSAGSAKGLCGTSGSFSRISSIHSMGSCRAPSLVGTVGSVSSFRTGFSGPGSCLPGSYLSSGCHSSGFAGSGGWFCEGAFNGNEKATMQILNDRLANYLEKVRQLEQENTQLECRIREWYECQIPYICPDYQSYFKTAEELQQKILLTKSENARLILQIDNAKLAADDFRTKYETELSLRQLVEADINGLRRILDELTLCKADLEAQVESLKEELLCLKRNHEEEVNALRSQLGDRLNVEVDAAPPVDLNKILDDMRCQYETLVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRTVNSLEIELQAQQSMRNSLESTLAETEARYSSQLGQMQCLITNVESQLAEIRCDLERQNHEYQVLLDVKARLESEIATYRRLLDGEDCKLPAHPCSTECKPAVRVPYIPSTTCTPAGPCTPAGPCTPAPQVSTQIRTITEEIRDGRVISSREHVVPRAM
What are the official names of this protein?
Keratin, type I cuticular Ha6, Keratin-36, K36, Keratin-5, MHRa-1, Type I keratin 48 kDa.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: VLTF1_VAR67
Sequence: MSIRIKIDKLRQIVAYFSEFSEEVSINVDSTDELMYIFAALGGSVNIWAIIPLSASVFYRGAENIVFNLPVSKVKSCLCSFHNDAIIDIEPDLENNLVKLSSYHVVSVDCNKELMPIRTDTTICLSIDQKKSYVFNFHKYEEKCCGRTVIHLEWLLGFIKCISQHQHLTIMFKDDNIIMKTPGNTDAFSREYSMTECSQELQKFSFKIAISSLNKLRGFKKRVNVFETRIVMDNDDNILGMLFSDRVQSFKINIFMAFLD
What is the function of this protein?
Associates with RNA polymerase to initiate transcription from late gene promoters.
What are the official names of this protein?
Late transcription factor 1, VLTF-1, Trans-activator protein GK1.
What is the protein family that this protein belongs to?
Belongs to the chordopoxvirinae VLTF-1 family.
Protein: DPO4_STRCO
Sequence: MRTAPTILHLDMDAFFASVEQASKPSLRGKAVVVGGLGPRGVVATCSYEARVFGVHSAMPMGQARRLAPHAAYLVPRFELYRSISEQVMRLLRELSPLVEPLSLDEAFVDLDAGGAARDAETARLAGTKLRTDIRTVTGLTGSVGLAASKMLAKIASEAAKPDGLVLIPPGTERAMLEPMTVRTLPGVGPATGDHLRRAGITTVGEIAEAGEDELVRLLGKAHGHALYAMALARDERPVVAERETKSVSVEDTYDVDIHDRVRVGVEVGRLADRCVRRLRASGLSGRTIVLKVRRYDFSTLTRSETLRGPTDDPAVVREAAARLLDSVDTTGGVRLLGVGVSGLADYTQEDLFAQAAGDRAEEPAEEPGTEPAEAHSPSPAERRWPSGHDVRHTELGHGWVQGSGLGRVTVRFETPYSGVGRVRTFLVDDPELTPADPLPLVADTEGGAGQPSSGPLPLPASLPKSWSGGGGAAATSRP
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZG48_XENLA
Sequence: MMSEEASGTVMGNKERIVTLTLEMIYLLTGEHYIPRKKSDDGGALHAPGSVIQKENNKNDKKILELMSNIIQLLTGEEWGCLKTNTISHGETKKENPQQLYLPDCDYEDKADININLNATVCFDNESNTNVDKGANRWEARNVPKSEFLPEEQPCAANSIKEESELCKAEYRPDCSFNPLGKQIQGTDTPTANVGSSMNSSLSDNYLLKTIKEEPDSCEEEKLSDYKIITVSEPVAEDQNPAPSCSQNNRSLPNYVSNTIKEEPYDEEHFSDYRIITVTDPTQVAGTSPHSTENGEYDSSMAACTSQLSKSALNVMFNCNVCHTAFNNKSNLVRHQRIHTGEKPFSCSECGKCFRQSSQLFLHRRNHTGEKPFSCSECGKCFKWRSLLIKHHKTHTGDKSFTCADCGKCFKKFSRLTEHRKCHTGEEPFVCSECGKSFAQSPQLDLHMRIHTGEKPFSCSDCGKCFTQRADLNVHRRTHTGEKPFTCSVCGKGFTRRTQLNIHNRIHTGENTFTCPECGKCFTQHSHLLAHQKGHMGKKPFCCSECGKRFRQSTQLYLHQKAHAGEKPFTCAECGQWFKLYSILVEHQKCHTGEKPFSCSECGKCFKRHTLLTEHQRIHTGENTFSCSVCGKCFTRHSHLTAHEKIH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Gastrula zinc finger protein XlCGF48.2.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBN_BUXMI
Sequence: METATLVAIFISGSLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CITD_ECO24
Sequence: MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDAIRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ
What is the function of this protein?
Covalent carrier of the coenzyme of citrate lyase.
What are the official names of this protein?
Citrate lyase acyl carrier protein, Citrate lyase gamma chain.
What is the protein family that this protein belongs to?
Belongs to the CitD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_BDEBA
Sequence: MSLNFTEYEAKWQKKWADAKAFQAETTSSKPKYYALDMFPYPSASGLHVGHMASYTPGDIISRYKRVNGFNVLHPMGYDAFGLPAEQYAIQTGVHPAITTKKAIDSFRKTLQTFGFSFDWSREISTCEPDYYKWTQFIFLKLYERGLAYQKEVPVNWCPALKTVLANDEVVDGKSERGGHPVIRVPMKQWMLKITDYAERLLNDLDKLDWPERTKEGQRNWIGKSEGARITFKVHGEKDTFEVFTTRPDTLFGVTFMVMAPEHPLVKKITSQPQYTAVENYIADTAKKSEVDRKASTEKTGVFTGAHATHPITGDKIEIWISDYVLMDYGTGAIMAVPGHDARDFEFATKFNIPIKSVLESDMLPFEGDSIMINSEFLDGLNKTEAISKMLKHLEENKLGVREVQYKLRDWLFSRQRYWGEPFPIVHFADGSKGVPVNELPVILPEVADYEPADTGEAPLARNADWVKYMDGDKEGRRETDTMPGAAGSSWYFLRYIDPKNTEAPFSPEAEKYWMPVDLYVGGPEHTVGHLLYARFWTKVLFDCGLVTHDEPFQKLAHQGMILGPDGEKMSKSRGNVISPEDIARSHGADALRTFISFMGPVDKDKPWAPTGIDGVKRFLDRITRLVVNDDGQLVATSEALTPEIEKLVHKTIKKVTEDIESMSFNTAISAMMILVNELYRAECRSVLAVKPLVQILAPFAPHLAEELWEKMNGEGLCALAPWPKYDNTLCADDTVTIGVQVNGKMRGTIEIGVAASEQEAVAAAKAVQQVAAVLGDKNPDKVIYKAGKILNLIVK
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRI14_FUSSP
Sequence: MLPQVILNHLGSIGEAASTWFSENKYFGSVGQCPPLPKGDLNYDIYMGYPEMFAWDKKRCVAYVSNLYNATVSTWDPYKSVVLDTIHFPGLSHAGNSASPNPLHASGIILRPDAYHAETLEVVIDNGDAFYSDGFNVSGPDHLMSIDLKTKEVTSQLRLNNGLYAGYADASLGPDGNTYVLGTYSSNILRVTPDKEISTFYVAEPLGPPRLYGFTGIAHVGDAMIVPDNIIGQLIRFDVRDKVGTPVTIKQTPYHEFKTANVLHFPERYNDTILLVAENMTPDYPYGGVSVYQDKTKQFNEVEFLGFLPSRLTNALTTSARQMADRIYVVALPTDGANITVAGESSRFPFQDITEELDLMILPEIKDEARDEI
What is the function of this protein?
Part of the core gene cluster that mediates the biosynthesis of trichothecenes, a very large family of chemically related bicyclic sesquiterpene compounds acting as mycotoxins, including T2-toxin (PubMed:11352533).  The biosynthesis of trichothecenes begins with the cyclization of farnesyl diphosphate to trichodiene and is catalyzed by the trichodiene synthase TRI5 (PubMed:3800398).  Trichodiene undergoes a series of oxygenations catalyzed by the cytochrome P450 monooxygenase TRI4 (PubMed:7651333).  TRI4 controls the addition of four oxygens at C-2, C-3, C-11, and the C-12, C-13-epoxide to form the intermediate isotrichotriol (PubMed:16917519).  Isotrichotriol then undergoes a non-enzymatic isomerization and cyclization to form isotrichodermol (PubMed:2317042).  During this process, the oxygen at the C-2 position becomes the pyran ring oxygen and the hydroxyl group at C-11 is lost (PubMed:2317042).  More complex type A trichothecenes are built by modifying isotrichodermol through a series of paired hydroxylation and acetylation or acylation steps (PubMed:11352533).  Isotrichodermol is converted to isotrichodermin by the acetyltransferase TRI101 (PubMed:10583973).  TRI101 encodes a C-3 transacetylase that acts as a self-protection or resistance factor during biosynthesis and that the presence of a free C-3 hydroxyl group is a key component of Fusarium trichothecene phytotoxicity (PubMed:10583973).  A second hydroxyl group is added to C-15 by the trichothecene C-15 hydroxylase TRI11, producing 15-decalonectrin, which is then acetylated by TRI3, producing calonectrin (PubMed:9435078, PubMed:8593041).  A third hydroxyl group is added at C-4 by the cytochrome P450 monooxygenase TRI13, converting calonectrin to 3,15-diacetoxyspirpenol, which is subsequently acetylated bythe acetyltransferase TRI7 (PubMed:12135578, PubMed:11352533).  A fourth hydroxyl group is added to C-8 by the cytochrome P450 monooxygenase TRI1, followed by the addition of an isovaleryl moiety by TRI16 (PubMed:12620849, PubMed:14532047).  Finally, the acetyl group is removed from the C-3 position by the trichothecene C-3 esterase TRI8 to produce T-2 toxin (PubMed:12039755).
What are the official names of this protein?
Core trichothecene cluster (CTC) protein 14.
What is the protein family that this protein belongs to?
Belongs to the TRI14 family.
Protein: PP175_ARATH
Sequence: MAIFSTAQPLSLPRHPNFSNPNQPTTNNERSRHISLIERCVSLRQLKQTHGHMIRTGTFSDPYSASKLFAMAALSSFASLEYARKVFDEIPKPNSFAWNTLIRAYASGPDPVLSIWAFLDMVSESQCYPNKYTFPFLIKAAAEVSSLSLGQSLHGMAVKSAVGSDVFVANSLIHCYFSCGDLDSACKVFTTIKEKDVVSWNSMINGFVQKGSPDKALELFKKMESEDVKASHVTMVGVLSACAKIRNLEFGRQVCSYIEENRVNVNLTLANAMLDMYTKCGSIEDAKRLFDAMEEKDNVTWTTMLDGYAISEDYEAAREVLNSMPQKDIVAWNALISAYEQNGKPNEALIVFHELQLQKNMKLNQITLVSTLSACAQVGALELGRWIHSYIKKHGIRMNFHVTSALIHMYSKCGDLEKSREVFNSVEKRDVFVWSAMIGGLAMHGCGNEAVDMFYKMQEANVKPNGVTFTNVFCACSHTGLVDEAESLFHQMESNYGIVPEEKHYACIVDVLGRSGYLEKAVKFIEAMPIPPSTSVWGALLGACKIHANLNLAEMACTRLLELEPRNDGAHVLLSNIYAKLGKWENVSELRKHMRVTGLKKEPGCSSIEIDGMIHEFLSGDNAHPMSEKVYGKLHEVMEKLKSNGYEPEISQVLQIIEEEEMKEQSLNLHSEKLAICYGLISTEAPKVIRVIKNLRVCGDCHSVAKLISQLYDREIIVRDRYRFHHFRNGQCSCNDFW
What is the function of this protein?
Involved in RNA editing event in chloroplasts.  Required for the editing of a single site in rps12 transcript.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At2g29760, chloroplastic, Protein ORGANELLE TRANSCRIPT PROCESSING 81.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MURB_CAUVC
Sequence: MTWKTQLPTARGKLLIDEALAPFTWFRVGGPADVVFLPADEQDLSDFLKGLDPSVPVMAIGVGSNLLVRDGGVDGVVIRLGKGFNGVEALGDNRIKAGSAVPDAILARKAAEAGIAGLEFYVGVPGTIGGAVIMNAGCYGAETVNVVKSVRVMNRAGVVRELSVEDLHYTYRHSALQDGEPVIVLDAIFEGTPDEPEAIKARMAEITARRETTQPIREKTGGSTFKNPPGHSSWKLVDEAGWRGKPYGGAMFSPLHSNFLINTGEATAADLEGLGEAVRADVLAKTGVQLDWEIKRIGRAG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.