PharMolix/UniProtQA huggingface dataset:
Protein: HIS1_NITWN
Sequence: MTTSLVLAVPSKGRLQENAEAFFARAGLTLAKPRGVRDYRGTIAELDNVEIAYLSASEIASQLARGTVHLGVTGEDLIRESIVDADKRVALITSLGFGNANVVVAVPQSWIDVRTMADLDDVATGFRAQHNRRMRVATKYINLTRAFFASHGVVDYRIVESAGATEGAPAVGTAEMIVDITTTGATLTANGLRVLDDGVILRSQANLVASREADWSNGARETARVILDHIAARARASKYREVRTRFPGCDAALLKEAHDRFGVVSPFGGPTSSGMVTLHCPPDRLYALASFLRLHGADTVSIASLDYVFDRDNPLFEKLEVFLRT
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_STRTD
Sequence: MSKAFLPTILEQKEKEVAQLVMEDLQPLRQTYRLYDFLKSNQNKLQIISEVKKASPSMGDINLDVDIVAQAKTYEENGAAMISVLTDEVFFKGDISYLKEISTQVAIPTLAKDFIIDEKQIVRSRNAGATVILLIVAALPEARLKELYDFATSLGLEVLVETHNLPELEVAHRIGAEIIGVNNRNLVTFETDINTSLELSTHFKDKPVYISESAIFTGQDAALVAPYFNGILVGTALMTADNVAKKVKELQIDKG
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RL33_PROA2
Sequence: MAKKENRVIITLECTEARKEGASPSRYTTTKNKKNQTERLVLKKYNPSLKKHTLHKEIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: DAPD_METCA
Sequence: MSLENIINEAFENRAQISPGTVGAEVREAVAEALRLLDSGAARVAEKKDGGWVVNQWLKKAVLLSFRINDNRVMDGGETRYFDKVEPKFGGFGPEEFRAAGVRVVPPAAVRRGAYIAPGVILMPSYVNIGAYVDSGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAGPTIIEDNCFIGARSEIVEGVIVEEGSVISMGVYIGQSTKIYNRMTGEISYGRVPAGSVVVSGNLPARDGSHSLYCAVIIKQVDEKTRGKVGINELLRD
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, Tetrahydrodipicolinate N-succinyltransferase, THDP succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_METBU
Sequence: MVEMFYDKDADLGALKGKIIAVMGYGSQGHAQAQNLHDSGLDVVIGLREGSRRWKQAEDDGLKVMTVADAAKAADVVQILLPDEIQSKVYYSEIEPGLEAGNSLVFSHGFNIHYNQIVPSKDLDVYMVAPKSPGHLVRRTYKEGAGVPGLIAVYQDASGNALEMALAHAKGVGCTRAGVIETTFREETETDLFGEQVDLCGGVASLIKTSFEVLVEAGYQPEMAYFETLHELKLIVDLIHEGGLEKMWYSVSNTAEYGGLTVGPQIINEESREAMYVALERIQNGEFAREFVLEGQTNHAVLTSMERLEKEHPVEVVGKKLRAMMPWLNSELNEE
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: USPB_SHISS
Sequence: MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVVSLIALMIWH
What are the official names of this protein?
Universal stress protein B.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PTH_AZOC5
Sequence: MFLFAGLGNPGPKYAGNRHNIGFMAVDAIVRRHRLSPWRRRFQGAVSEGEIAGEKVLALLPETFMNESGRAVAEAAKFYKIPLENIFVFHDELDLPPAKIRVKKGGGNAGHNGLRSITAQCGNDYWRVRLGIGHPGDKSLVHSYVLNDFGKAEREWVEAVNTACADFAPALIGGKAEDFQNRAHLFLEAQGFTDVKPLGGARAS
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_IDILO
Sequence: MIYQGESIRVDFIEPGFAELQFDAKGSVNKFDQATLEEFSEALTKLQNTDDLRGVIVTSSKSTFIVGADITEFLTLFSDQEKTRSWVAKASRVFDQLEDLPVPTVGAVTGFALGGGCEALLACDYRVADTTATIGLPEVKLGLIPGFGGTMRLPRVIGPDNALEWITTGKNNKALDALKVGAVDAVVEPENLTKAALNLAKAAAAGQQDWKAKRQPKLEPLKANDTELMMTLVTAKGMIAAKAGKHYPAPHKALEAIENGAREHREGALTAENNAFFDLTQTEACQAQVGIFLADQAVKGKSKKYAKAATKEIKTAGVLGAGIMGGGIAYQSALKGVPAVMKDIKQDALDLGMKEAGKILKKGVERGKVNNEKMIKILSSITPTLLNDAVKDVDIVVEAVVENPKVKGSVLAEIEGVIGDDAILTSNTSTISITELAKNLKRPEKFCGMHFFNPVHKMPLVEIIRGEKTSDDTVNAVVAYALKLGKTPIVVNDCPGFLVNRVLFPYLAGFAGMVDEGVDFVGIDKVMEKQFGWPMGPAYLSDVVGIDTADHCTVVMEAGFPTRMKRDESSAIAKLAAAERYGQKNGKGFYVYGTDKKGKPTKEADPATYELLGCEQGKKLDADEVIARCMIPMVNEVVRCLEEDIVGSAAEADMALLYGLGFPPFRGGPFRYLETLGMDNFIQLADKYAHLGEIYQVTDGMREMAKAGKSYFDTTSAK
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: RL6_THEYD
Sequence: MSRIGRKPIQIPDNVNVTVENRQIIVKGPKGQLSYSLPEGIGITIDNKTMLITRESDLSKQRALHGLARSLISNMVTGVSQGFTKALQIYGVGYRAQVSGNKIILNIGYSHPVEFVLPEGIKATVDEKQTTITLHGIDKQLVGQIAANLRAIRPPDAYKGKGIRYTDEVLKLKPGKTGKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LTR3A_XENLA
Sequence: MAEELRRFLYKKLTSVEGLHAIVVSDRDGVPVIKVANENAPEQALRPAFLSTFALATDQGSKLGLSKNKSIICYYSTYQVVQFNQLPLVVSFIASSNANTGLILSLEKELGSLFKELRQAVIS
What is the function of this protein?
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids.  As part of the Ragulator complex, may activate the TOR signaling cascade in response to amino acids.  Adapter protein that may regulate the MAP kinase cascade.
What are the official names of this protein?
Ragulator complex protein LAMTOR3-A, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3-A, Mitogen-activated protein kinase scaffold protein 1.
What is the protein family that this protein belongs to?
Belongs to the LAMTOR3 family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YQGE_SALSV
Sequence: MNLQHHFLIAMPALQDPIFRRSVVYICEHNQDGAMGIIVNKPLENLQIEGILEKLKITPEPRDSAIRLDKAVMLGGPLAEDRGFILHTPPSRFASSIRISDNTVITTSRDVLETLGTQQQPSDVLVALGYASWDKGQLEQELLDNAWLTAPADLNILFKTPIAERWREAAKLIGIDILTMPGVAGHA
What are the official names of this protein?
UPF0301 protein YqgE.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: NDK_STAMF
Sequence: MNTERTLVLIKPDGVRRGLIGEIISRFERKGLKIKALKMLRLTREKAEEFYSVHRGKPFFVSLIEFMTSGPIIAMILEGDMAISVVRRMIGPTDGREAPPGTIRGDYSLSKSQNVVHASDSPESAMREIRVIFKDDEIIDW
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUXP_PHOLE
Sequence: MFRGIVQGRGVIRSISKSEDSQRHGIAFPEGMFQLVDVDTVMLVNGCSLTVVRILGDMVYFDIDQALGTTTFDGLKEGDQVNLEIHPKFGEVVGRGGLTGNIKGTALVAAIEENDAGFSVLIDIPKGLAENLTVKDDIGIDGISLPITDMSDSIITLNYSRDLLASTNIASLAKDVKVNVEILNEW
What is the function of this protein?
Antenna protein that modulates the color of the bioluminescence emission of the luciferase.  In the presence of LumP, luciferase emission is shifted to higher energy values (shorter wavelength).
What are the official names of this protein?
Lumazine protein, LUMP.
Protein: SP9_XENTR
Sequence: MATSILGEEPRFGTTPLAMLAATCNKIGNTSPLSSLPESSAFAKGGFHPWKRSSSSCSLGSSLGGFAVATSRASGALTGGTATANSAFCLASTSPTSSAFSSDYSGLFSSASGVSPQESAGQSAFISKVHASAEGLYPRVGMAHPYESWYKSGFHSDVSGGASAWWDVHAAGPSTWLEVQNTQGALHSGAAAHGQLGAYSPDFSSLTHSAFSSTGASHLLPGGQHLLTQDAFKPVLPSYPDSGGPMLSGAAGTGAGGTGRSARRYSGRATCDCPNCQEAERLGPAGASLRRKGLHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLSKHIKTHNGGGGGGKKGSDSDTDASNLETPRSESPELIMEGVRPGKDSGNDS
What is the function of this protein?
Transcription factor which plays a key role in limb development.  Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
What are the official names of this protein?
Transcription factor Sp9.
What is the protein family that this protein belongs to?
Belongs to the Sp1 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PA_INBLE
Sequence: MDTFITKNFQTTIIQKAKNTMAEFSEDPELQPAVLFNICVHLEVCYVISDMNFLDEEGKTYTALEGQGKEQNLRPQYEVIEGMPRNIAWMVQRSLAQEHGIETPRYLADLFDYKTKRFIEVGITKGLADDYFWKKKEKLGNSMELMIFSYNQDYSLSDESSLDEEGKGRVLSRLTELQAELSLKNLWQVLIGEEEIEKGIDFKLGQTISKLRNISVPAGFSNFEGMRSYIDNIDPKGAIERNLARMSPLVSVTPKKLKWEDLRPIGPHIYNHELPEVPYNAFLLMSDELGLANMTEGKSKKPKTLAKECLERYSTLRDQTDPILIMKSEKANENFLWRLWRDCVNTISNEETGNELQKTNYAKWATGDGLTYQKIMKEVAIDDETMYQEEPKIPNKCRVAAWVQAEMNLLSTLTSKRALDLPEIGPDVAPVEHVGSERRKYFVNEINYCKASTVMMKYVLFHTSLLNESNASMGKYKVIPITNRVVNEKGESFDMLYGLAVKGQSHLRGDTDVVTVVTFEFSSTDPRVDSGKWPKYTVFKIGSLFVSGREKPVYLYCRVNGTNKIQMKWGMEARRCLLQSMQQMEAIVDQESSIQGYDMTKACFKGDRVNNPKTFSIGTQEGKLVKGSFGKALRVIFTKCLMHYVFGNAQLEGFSAESRRLLLLIQALKDRKGPWVFDLEGMYFGVEECISNNPWVIQSAYWFNEWLGIEKEGSKVLESIDEIMDE
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: TYB10_PIG
Sequence: MADKPDMGEINSFDKAKLKKTETQEKNTLPTKETIEQEKQAK
What is the function of this protein?
Plays an important role in the organization of the cytoskeleton.  Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
What are the official names of this protein?
Thymosin beta-10, Thymosin beta-9.
What is the protein family that this protein belongs to?
Belongs to the thymosin beta family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: YPD1_CANAL
Sequence: MSEDKLQKLQDSGLVDWAVFSEIVTMDEDEEGFSKSLVEVFVSQVEETFEEIDKYLKEKNLEKLSSSGHFLKGSAAALGLTKISNQCERIQNYGHKINFDNFQLEDIKTKGDSAVSAENVAVNDGETNPENGSNGNETSNNKTNTSNIPDESSDDFWIALIEDALAKARDGFDQSRRALDEYYE
What is the function of this protein?
Phosphorelay intermediate protein that is part of the bifurcated SLN1-YPD1-SKN7/SSK1 two-component regulatory system, which controls activity of the HOG1 pathway and gene expression in response to oxidative stress and probably to changes in the osmolarity of the extracellular environment.  Catalyzes the phosphoryl group transfer from the membrane-bound histidine kinase SLN1 to two distinct response regulators SSK1 and SKN7.
What are the official names of this protein?
Phosphorelay intermediate protein YPD1.
What is the protein family that this protein belongs to?
Belongs to the YPD1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DNLJ_AGRFC
Sequence: MSKDQIPVENLTELEASSELAFLAAELARHDALYHGKDAPEISDADYDALKRRNDAIEAAFPALVRADSPSKKVGFTPLPTFAPIVHARPMLSLDNTFSEEDLRDFVSSVYRFLGHLPDDSIAFTAEPKIDGLSMSIRYENRKLKTAATRGDGTTGENVTANIRTIKEIPNELPADAPDVVEVRGEVYMAKSDFLALNAQMEADGKQTYVNPRNTASGSLRQLDANVTAKRKLRFFAYALGEVSNGGQPARIADTQYGIVEKFREWGFPVNPLMKRFTSAQQLLEHYNEIGVARPDLDYDIDGVVYKVDRLDLQERLGFRSRSPRWATAHKFPAEQAFTTVENIEIQVGRTGALTPVARLTPITVGGVVVTNATLHNADYIEGIGNSGERIRPEDHDIRIGDTVIVQRAGDVIPQVLDVLLEKRAAGAAKYVFPEKCPVCGSHAVRERNEKTGKLDSVTRCTGGFVCRAQAVEHLKHFVSRNAFDIEGLGTKQIDFFFESDDPALSIKTAPDIFTLKARQEASHLTKLENIDGFGKVSVKKLFDAIDARRAIDLHRLIFALGIRHVGETTAKLLARSYGTYEHFEKAMKAAADPASDAWAELNSIDGIGEVVARAIIEFYKEPRNLDVIDRLIRELQPKEAEKPSTEGSPVAGKTVVFTGSLEKFTRDEAKARAESLGAKVAGSVSKKTDILVAGPGAGSKLAKATELGVQTMDEDEWLALIGG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CP4C1_BLADI
Sequence: MEFITILLSTALFIVTFLFLFRQGAKRARFVYLVNKLPGPTAYPVVGNAIEAIVPRNKLFQVFDRRAKLYGPLYRIWAGPIAQVGLTRPEHVELILRDTKHIDKSLVYSFIRPWLGEGLLTGTGAKWHSHRKMITPTFHFKILDIFVDVFVEKSEILVKKLQSKVGGKDFDIYPFITHCALDIICETAMGIQMNAQEESESEYVKAVYEISELTMQRSVRPWLHPKVIFDLTTMGKRYAECLRILHGFTNKVIQERKSLRQMTGMKPTISNEEDELLGKKKRLAFLDLLLEASENGTKMSDTDIREEVDTFMFEGHDTTSAGICWALFLLGSHPEIQDKVYEELDHIFQGSDRSTTMRDLADMKYLERVIKESLRLFPSVPFIGRVLKEDTKIGDYLVPAGCMMNLQIYHVHRNQDQYPNPEAFNPDNFLPERVAKRHPYAYVPFSAGPRNCIGQKFATLEEKTVLSSILRNFKVRSIEKREDLTLMNELILRPESGIKVELIPRLPADAC
What is the function of this protein?
Involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Cytochrome P450 4C1, CYPIVC1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: GLYC_RSVT
Sequence: MHFKSYFIYTTIFNMAWGAPIPFPDTHSWMRNREREPSEIVKVPCSARAPPCKLTYELNGYFIENGLICYNRASVNYFETCYTGNYDYKLPLHPSFSKFGGHVYLSCDDAILQNVSLVGIQQTEYTSSPLLITNSNSEKISYSNLKTGFLGIVYAVETRACIQPDQAKKPEEIINHGVAIKPSCTDGVLYYINSACEVNVSDQTFSIPSCESVKLPTYDDTIEVCDKGGCQNVTCHPGEICDKYERMDMIMRIKNYQCSHIYRYSLYSIILFFVIVIVFTLITIMNILFFLKPAFWLLKKVLYSMVGLCHRRPVVDEVSVDMSTVRVVDEAEEGLLVVEDSIAPNTNVSDKVKRKGRKVENGLIFIPYVLMILLLVCSAESCQDLVSSISNIERCTNNSCDFISKMKLTLLNTPQDFCFKTSTDVYKIRFNSVRVMCLSVPLYYTNSFKRVISREEWKCFEGEGCRTDGTHSIWGESTSLSFDYCVTDFHIFSYCPAYHYNWKRIEYEPTSSRACTIMKCMDTKFEIVGYIQKNGHVLKELGGITSKYDSPLVSISLSNYNSARMPREYAECDGKAYLRTANDLGSFDKELLGNIQCPTKEDAVVLSSKCKTKILSNEDLPVIRYIERDGVDMLEHVKSEPLKDVLVSSSGISLSTLDLFPVELNLQFKEAITSIITSKISLNGTSCKITGIERKFKKTTVSIESSNKVYLSDILACEGLAVCPMILNNIKKGTCITTTYYSVTVGSMIKCKFIYSGDTLMCKYDVSPLEITVISPSLDVSSFEAVKTSTTNWMELLAGIVKDNPKLSLVASIIPIGLILKTIRSFLDDIRQVD
What are the official names of this protein?
Putative envelope glycoprotein, GP, Protein pc2.
What are the subcellular locations of this protein?
Note=Filamentous electron-opaque inclusion bodies in plant and insect cell cytoplasm.
Protein: ACCD_STAES
Sequence: MFKDFFNRSKKKKYLTVQDSKQNDVPAGIMTKCPKCKKIMYTKELNENLNVCFNCDHHIALTAYKRIEAISDEGSFIEFDRGMTSANPLDFPGYEEKIEKDQQKTGLNEALVSGTAKLDGIQYGVAVMDARFRMGSMGSVVGEKICRIIDYCTEHRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYITNPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVIHRKDMRETLSNILKIHQEVSN
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MALT_SHIBS
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIATVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAEFNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: SAHH3_MOUSE
Sequence: MSVQVVSAAAAAKVPEVELKDLSPSEAEPQLGLSAAAVGAMVPPAGGGDPEAPAPAPAAERPPAPGPGSGPTAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVKKQIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNSKGSSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTAVLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVEGWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYVTEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNKNGPFKPNYYRY
What is the function of this protein?
May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg(2+)-sensitivity.  On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1,4,5-trisphosphate.
What are the official names of this protein?
Putative adenosylhomocysteinase 3, AdoHcyase 3, Long-IRBIT, S-adenosyl-L-homocysteine hydrolase 3, S-adenosylhomocysteine hydrolase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm. Microsome. Note=Associates with membranes when phosphorylated, probably through interaction with ITPR1.
Protein: CL056_MOUSE
Sequence: MGSESLETLQVILSGGEFMLHTSVWLVPGSLLSSHPVFTFKVKQENNGPTFWRRKVSRTLNESSLRSQQESSTPFKDPTSHPSDLKELSPAGQGTSRPLPTLSSCQSMAATDMPVCSLSLASSTNEPQELPDPRDAPREGSFRLDGNQSEFGLGNSLPASPLHSCRNLEKEESELHLYIISATSSIFLHLKSSWNNYIIRATLLQDPLCASEHNDVIGKPKPYRSEEKIKHFCQLKSELFLKDNTLRKILCLITELRVAAQRNFILKRLFWKTSELFYFLVNKLHEYLPESRDKHALQNKSQRADELMACIEIIQTLGLMFRETEIESSRLNTLAAKKGTLFNLLVILISKPKVPKSCSKSDAQPVADPTSAEVFFDSQLQKLTLEYTDTATALLYEILLIFQQGNLGLGSTKFAISWMMSFLQSCPPIMAFVARIVEGVVRGLSASFQLLTPCQAVLLYQQFYILRSCLQHSKALAEYIRNDHREEFRYFIHMPALEQRLPGCYPITEPTTQLCHEVLQLIEQKQCAKC
What are the official names of this protein?
Uncharacterized protein C12orf56 homolog.
Protein: IOLG_PARDP
Sequence: MTLKIGVIGTGAIGQDHTRRINQVLAGARVAALNDVNRANAEACQRDHAPEARIFDDPHALIRDAEVDAILVCSWGQTHEEYVLAAIAAGKPCFCEKPLATTAEGARRIVEAEEAAGKRLVQVGFMRRYDPGYVALKKAVAEVTGAPLMVHAAHRNPRVGENYLTPMAIHDTLIHEIDVLRWLLDDDYVGARVLFPRKSPRAHEKLRDPQVVVLETARGVVIDVEVFVNCHYGYDIQCEIVGEDGIARLPEPMGIQTRSGAVLGQPILMDWKDRFIDSYDYELADFLKAAARGTAAGPTAWDGYVAAVTADACVAAQEAGGESVAIELPARPALYA
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: HFQ_YERPP
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPSPPVSHHSNTPSGSTNNYHGSNPSAPQQPQQDSDDAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CYB_HYLNI
Sequence: MTNIRKTHPLIKIVNHSFIDLPTPSNISAWWNFGSLLGFCLIIQIITGLFLAMHYTSDTVTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYIYFETWNIGVILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFVLPFIIAALAMIHLLFLHETGSNNPSGLISDSDKIPFHPYFSIKDLLGVLILLLIFMNLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILMLFPILHLSKQRSMMFRPLSQCFFWILVADLFTLTWIGGQPVEHPFIIIGQTASILYFTIILVILPFISLLENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ZO15_XENLA
Sequence: TGEKPFTCKECSKSFSSNSHLSRHQKIHSGVKSFTCTECDKKFLTRSSLLLHQKVHTGEKPFICTECGKGFSAKSQLHRHHVIHTGDRPFTCAECGKTFSYKQSLVTHRAAHTREKPFICTECGKSFSHKNNLQTHLKSH
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Oocyte zinc finger protein XlCOF15.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.