PharMolix/UniProtQA huggingface dataset:
Protein: SURE_BRUSI
Sequence: MRILLTNDDGIHAEGLAVLERIARKLSDDVWVVAPETDQSGLAHSLTLSEPLRLRQIDARHFALRGTPTDCVIMGVRHVLPGAPNLVLSGVNSGANMADDVTYSGTVAGAMEGTLLGVRAIALSQEYEYAGDRRIVPWETAEAHAPELIGRLMEAGWPEGVLLNLNFPNCAPEEVKGVRVTAQGKLSHDARLDERRDGRGFPYFWLHFGRGKAPVADDSDIAAIRSGCISVTPLHLDLTAHKVRAELGAALGVEA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAR1_CRYNJ
Sequence: MSGRGFSRGGGGGFRGGARGGRGGGRGGFQQRDMGPPDTVLEIGSFQHDVESEMLCSLTAPTKIPYFNAPIYLQNKTQIGKVDEILGPINEVYFTVKMEQGMLASSFKKEDKVYISGEKLLPIERFLPKPKVAGGKERGAQGGRGAPRGRGGAGSRGGRGGFSSRGGPGGRGGARGGAGGRGGFSSRGGGAPRGRGGFRGRGQ
What is the function of this protein?
Non-catalytic component of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP), which catalyzes pseudouridylation of rRNA and is required for ribosome biogenesis.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs.  The H/ACA snoRNP complex also mediates pseudouridylation of other types of RNAs.  The H/ACA snoRNP complex mediates pseudouridylation at position 93 in U2 snRNA.
What are the official names of this protein?
H/ACA ribonucleoprotein complex subunit GAR1, snoRNP protein GAR1.
What is the protein family that this protein belongs to?
Belongs to the GAR1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GSA_CLOK1
Sequence: MRNDKIFEESKLYMPGGVNSPVRAFKDVPLNPPVIKKGRGAYIYDEDGNEYIDFVCSWGPMILGHCDEDVVNAIKYTSENAISFGATTKIELELSKYICTTMDNIEMIRMVNSGTEATMSAVKLARGYTRRNKIIKFSGCYHGHFDDFLVEAGSGVMTEGIPGSAGVPKDSIKNTIIAEYNNLEDVKNIFNKYGSDTAAIIVEPVAGNMGVIPGRIDFLKGLRKLCDEYGSLLIFDEVMSGFRVAYKGAQSLYGIKPDITTMAKIMGGGLPCGAYGGRKDIMENLSPLGPVYQAGTMSGNPIVMAAGLATLKKLNENPDYYVKLEKLGKKLEKGIKQISKDKNIPMVINRCGAMFSIFFTSDSEVKNYKDARKCDTTIFAKFFQHMLERGIYIAPSQFEAIFLNVKHTEEHIDKFLQAVNTF
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_LOCMI
Sequence: MYNNSMKLLFLSSLMMGTYLSISSTPWLGTWMGLEINLLSIIPMLTDNKNSMINEPAIKYFIIQSMASTMLLISILIIQMKYMMWWDNKNIPSMMIMSSMMMKMGAAPFHFWLPEVMSSTSWINCLMLMTWQKIAPMMTMSYCIKMSSFLFVVIMMGIIVGAMGGLNQTSLRQILAYSSISHLGWMISSMTISENTWEFYFLIYSTLNVIIIFMFKTMNLFFLNQIYSASYFKTEIKFMMMTSLLSLGGLPPMLGFLPKWIVMQSLIDNKMTALVLLMITFTTITLYYYMRISFSAIIMLHNENSWLTSIKMNKLVVALPILSMISTMGLICTSNFMLLLSS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: NUOI1_MYCPA
Sequence: MFTFLKLIAGFRVTFSAMFKKPVTEGYPEKPGPVAPRYHGRHQLNRWPDGLEKCIGCELCAWACPADAIFVESADNTEAERFSPGERYGRVYQINYLRCIGCGFCIEACPTRALTMINDYEMADDNRADLIYGKDQLLAPLQPGMAAPPHPMAPGSTERDYYLLDNIAAANREAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 1, NADH dehydrogenase I subunit I 1, NDH-1 subunit I 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RS11_BURMA
Sequence: MAKASNTAAQRVRKKVKKNVAEGVVHVHASFNNTIITITDRQGNALAWATSGGQGFKGSRKSTPFAAQVAAESAGRVAMEYGVKNLEVRIKGPGPGRESAVRALHGLGIKITAISDVTPIPHNGCRPPKRRRI
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: UVRA_STAAS
Sequence: MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSR2_SCHPO
Sequence: MTLDQVRIPFLVEQTYPIIVPSYAGWFDMSKIHDIERRSNPEFFNGKSPLKTPSIYKDYRDFMINSYRLEPNEYLTVTACRRNLVGDVCAIIRVHAFLEQWGLINYQIDPETRPAFRLPPISGHVQAISNTPIVTQEMLAQHPPPSTVGGSSSQEFVKLEEKHYSPSLNAMEQTSPKEEDEKSDKVPRVDKVCFTCGVNCSQTWYHNLKNKKYDICPNCYKQGRFSSSFNSSDFLCMDAIDFNHDEEKPWSNQETLLLLEAIETYGDDWNQIALHVGSRTKEQCLIHFLQIPIEDPYRQKLQGDFSPFKKGFLPFDENENPVLSTLTYLASIVQQGMKERKQNESVKQGETSFGNSEFKNPLERVAYYALKSAAQKAKLIAAFENRQLRRLVFSLIQAQLEKLQLKMKVLEQLEKMCSLELSELDLRGKNLLLSRLSTKKMLLAFNKKLEEAVNLGGEDGLKIIDDLMSTEHAEALLTFEMPTATTVSPLSKQYPDKFRTIAL
What is the function of this protein?
Component of the chromatin structure remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning.  Controls particularly membrane and organelle development genes.  Part of the SWI/SNF complex, an ATP-dependent chromatin remodeling complex, required for the positive and negative regulation of gene expression of a large number of genes.  It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.
What are the official names of this protein?
SWI/SNF and RSC complexes subunit ssr2.
What is the protein family that this protein belongs to?
Belongs to the SMARCC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: YHV5_SCHPO
Sequence: MADRLRSQAKLEQLQARYVGVGNAFTTKYEWMVNQHRDTLSSVVGHPPLLAYMATALGEPRVQVRKNLLEKMIMPCGPPPPSNQF
What are the official names of this protein?
Uncharacterized protein C211.05.
What is the protein family that this protein belongs to?
Belongs to the SF3B5 family.
Protein: MKS1_ARATH
Sequence: MDPSEYFAGGNPSDQQNQKRQLQICGPRPSPLSVHKDSHKIKKPPKHPAPPPNRDQPPPYIPREPVVIYAVSPKVVHATASEFMNVVQRLTGISSGVFLESGGGGDVSPAARLASTENASPRGGKEPAARDETVEINTAMEEAAEFGGYAPGILSPSPALLPTASTGIFSPMYHQGGMFSPAIPLGLFSPAGFMSPFRSPGFTSLVASPTFADFFSHIWDQD
What is the function of this protein?
Regulator of plant defense response.  May contribute to MPK4-regulated defense activation by coupling the kinase to specific WRKY transcription factors.
What are the official names of this protein?
Protein MKS1, Protein MAP kinase 4 substrate 1, VQ motif-containing protein 21, AtVQ21.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNH3_STRZP
Sequence: MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVSIYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFVTPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAVSVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFCAKLHFKNTEKAKNA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_ACIB5
Sequence: MPRSLKKGPFVDAHLFAKVEAAVASNSRKPIKTWSRRSMILPDFVGLTISVHNGRNHVPVIVTEHMVGHKLGEFAPTRTYRGHGVDKKSKR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: SAHH_BURM9
Sequence: MNAAVIDSHSAQDYVVADIALAGWGRKELNIAETEMPGLVQIRDEYKAQQPLKGARIAGSLHMTIQTGVLIETLKALGADVRWASCNIFSTQDHAAAAIVEAGTPVFAFKGESLDEYWEFSHRIFEWPNGEFANMILDDGGDATLLLILGSKAEKDRSVIARPTNEEEVALFKSIERHLEIDGSWYSKRLAHIKGVTEETTTGVHRLYQMEKDGRLPFPAFNVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVAGYGDVGKGCAQSLRGLGATVWVTEIDPICALQAAMEGYRVVTMEYAADKADIFVTATGNYHVINHDHMKAMRHNAIVCNIGHFDSEIDVASTRQYQWENIKPQVDHIIFPDGKRVILLAEGRLVNLGCATGHPSFVMSNSFTNQTLAQIELFTRGGEYANKVYVLPKHLDEKVARLHLARIGAQLSELSDDQAAYIGVSKAGPFKPDHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARM1_DROSI
Sequence: MSSLRPDEARKLATAASVSPLSNCQFCGVVISSIADEQKLEFTNKYKGSCTLLCSYDSQGVVLRVVSDDDRSHVLKEYMIAADTDAAQMGRRSYAVSLDADNLVLRFGSEQDQQLFRKVVENVKHLRPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPMGYMLYNERMLETYLHARKWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISIPLEFHILQTGICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDVTIDLHIEGTLISSSNTLDLKNPYFRYTGAPVQAPPGTSTQSPSEQYWTQVDTQGSRNSSSMLNGGLSVNGIGDGMDITHGLMHPH
What is the function of this protein?
Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins.  May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling (By similarity).
What are the official names of this protein?
Histone-arginine methyltransferase CARMER.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RAB5A_CANLF
Sequence: MANRGATRPNGPNTGNKICQFKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDITNEESFARAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQSYADDNSLLFMETSAKTSMNVNEIFMAIAKKLPKNEPQNPGANSARGRGVDLTEPTQPTRSQCCSN
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes.  Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:8521472).  RAB5A is required for the fusion of plasma membranes and early endosomes.  Contributes to the regulation of filopodia extension.  Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan.  Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3 (By similarity).
What are the official names of this protein?
Ras-related protein Rab-5A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Cytoplasmic vesicle. Cell projection, ruffle. Cytoplasm, cytosol. Membrane. Cytoplasmic vesicle, phagosome membrane. Endosome membrane. Note=Alternates between membrane-bound and cytosolic forms.
Protein: VM2JT_PROJR
Sequence: MIQVLLVTICLAVFPYQGSSIILESGNIDDYEVVYPRKVTALPKGAVQQKYEDTMQYEFKVNEEPVVLHLEKNKGLFSKDYSETHYSPDGREITTYPPVEDHCYYHGRIQNDADSTASISACNGLKGHFKLQGETYFIEPLKLPDSEAHAVFKYENVEKEDEAPKMCGVTETNWESDEPIKKLSQIMIPPEQQRYIELVIVADHRMYTKYDGDKTEISSKIYETANNLNEIYRHLKIHVVLIGLEMWSSGELSKVTLSADETLDSFGEWRERDLLQRKRHDNAQLLTGMIFNEKIEGRAYKESMCDPKRSVGIVRDHRTRPHLVANRMAHELGHNLGFHHDGDSCTCGANSCIMSATVSNEPSSRFSDCSLFQYSSDIIHNPFTSRCLYNEPSKTDIVSPSVCGNYYMEVGEDCDCGPPANCQNPCCDAATCRLTPGSQCADGLCCDQCRFMKKGTICRIARGDDLDDYCNGISAGCPRNPFHA
What is the function of this protein?
Snake venom zinc metalloproteinase that inhibits ADP-induced human platelet aggregation (IC(50)=120 nM (native) and IC(50)=248 nM (recombinant)).  May act by binding to the receptor GPIIb/GPIIIa (ITGA2B/ITGB3) on the platelet surface (PubMed:14511668).  Degrades the alpha-chain of fibrinogen completely and the beta-chain partially, leaving the gamma chain intact (Ref. 2).  Also inhibits the growth of several cell lines, including human liver cancer cells (Bel7402), human leukemia cells (K562) and human gastric carcinoma cells (BGC823) (PubMed:19732785).
What are the official names of this protein?
Zinc metalloproteinase-disintegrin jerdonitin, Snake venom metalloproteinase, SVMP.
What is the protein family that this protein belongs to?
Belongs to the venom metalloproteinase (M12B) family. P-II subfamily. P-IIb sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: IFG15_HUMAN
Sequence: MFSDNSHCPDCGQQWFPSLELGHWLYQTELVENECYQVFLDRINRADYCPECYPDNPANRSLVLPWSFPLEWAPQNLTRWTFEKACHPFLLGPPLVRKRIHDSRVAGFNPALQLILTRTDKTLNKKLGQNK
What are the official names of this protein?
Torsin-1A-interacting protein 2, isoform IFRG15, 15 kDa interferon-responsive protein, IFRG15.
Protein: ARGC_AERHH
Sequence: MLNTVIVGASGYAGAELAALVQNHPQLKLFGLYVSAGSQDAHKRFSSLHPQWVGALDQPLLPLDEDGMTRILTQADLVLLATAHEVSATLAPKFLAKGLPVFDLSGAFRVRDQQFYASYYGFTHDSEQWLDQAAYGLAEWNAEAVKAAQLIAVPGCYPTASLCALKPLQQAGLIAKGWQPIINAVSGVSGAGRKAAINTSFCEVSLNPYGTFNHRHQPEISHHLGKEVLFQPHLGNYVRGILATIYVQLADGVTPTQVDQAYLKAYEGKPLVRLTGQMPSIRGVAGTPYCDLAWQQQGNMLVVVCAIDNLLKGAASQAMQCINIKFGFEPATGLI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGC_NITEU
Sequence: MKVQPAVQTNDNPRFVSTLTRNTLALILAGGRGTRLKNLTDWRAKPAVPFGGKFRIIDFTLSNCVNSGVRRIGVVTQYKAQSLIRHIQRGWSFLDGRFQEFIELLPAQQRTEEGTWYQGTADAVFQNLDILRTHNPGYVLILGGDHIYKMDYGRILAEHVERQADLTIACLEVPVEDASAFGVMAVDDSWRTTSFAEKPEHPAPIPGKPGHALISMGIYVFNAKFLYEQLIQDHDMDQSSHDFGKDVIPRLVASNARVYAHRFQNSCVNMASGVPYWRDVGTVDAYWKANIDLTTITPDLNLYDEDWPIWTHQEQLPPAKFVFDDDDRRGQALDSMVSGGCIISGATVRRSLLFSNVQIRGYSTIEDSVILPNVSIDRHAYLKRVVVEKECQIPEGLKVGFNPDEDRKHFYVTDDGITLITPEMLGQGIHYIR
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: EFM7_DEBHA
Sequence: MSDDEFIDTGLFAEPEGFTPPPPPPHFAKYQRKNKTDPAELNLRLVGKSPLWGHLLWNAGVFTADYLDKHADELVTGKDVLELGAAAGLPSLICGINKCNRVVCTDYPDPDLISNIQHNFDHCQGLDLSKTVVKGFIWGADAKPLMDDSEKEIQNEDKFDLVILSDLVFNHTEHLKLLKTCRDTVKKNGKCLVVFSPHRPKLLENDLEFFRTCEDFQFKAEKIDLVTWKPMFEEDDESIDIRARVYSFFLVPQW
What is the function of this protein?
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
What are the official names of this protein?
Protein N-terminal and lysine N-methyltransferase EFM7, Elongation factor methyltransferase 7.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_THET2
Sequence: MRWAIVRFPGANCDEDARFALEKAGIRAEFVWHTERDLRGFDGVFLPGGFSYGDYLRAGALAAKSPVMEAVRRFAEEGRYVVGVCNGFQILTEAGLLPGALLANLNLHFTCKEVGVRVERNDLPFTRLYPRGQVLRLPIAHGEGRYYADPETLARLEGEGLVVFRYAPLKDEADYNPNGSLHDIAGIVSEKGNVLGMMPHPERAVDEVLGNTDGLPFFLGLVREVAR
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BURMA
Sequence: MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPLGKRVSTVVLPDGEAYKNWETLNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALSTLPDRELAAGVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAAHLPTRAPDLGDARYVELMRVDKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_SHIB3
Sequence: MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQEDMMRLLRGN
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: RS15_FUSNN
Sequence: MRTKAEIIKEFGKSEADTGSTEVQIALLTEKINHLTEHLRVHKKDFHSRLGLLKMVGQRKRLLAYLTKKDLEGYRALIAKLGIRK
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: COMB_MICAN
Sequence: MQVFIYHTPELTPVHTLPDCAVVIDVLRATTTIATALNAGAEAVQTFSDLKTLMQVSDTWQPEKRLRAGERGGAKVEGCDLGNSPLDCTPDLMKGRRLFISTTNGTRALQRVEESPIVITAAMINRQAAVNYLLDKQPDTVWIVGSGWEGGYSLEDTACAGAIADALQEQSGQMAIGNDEVIASIALYRQWQNDLLGMFHSCSHGQRLLRLHCQEDLKYCANIDSLDVLPIQKEPSILVKL
What are the official names of this protein?
Probable 2-phosphosulfolactate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the ComB family.
Protein: NDUS6_MOUSE
Sequence: MAAVLTFRRLLTLPRAARGFGVQVSPSGEKITHTGQVYDEKDYRRVRFVDRQKEVNENFAIDLIAQQPVNEVEHRIIACDGGGGALGHPKVYINLDKETKTGTCGYCGLQFKQHHH
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial, Complex I-13kD-A, CI-13kD-A, NADH-ubiquinone oxidoreductase 13 kDa-A subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFS6 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: IER5L_XENTR
Sequence: MECALDAQSLISLSLRKIHSSRTQRGGIKLHKNLLVSYVLRNARQLYLSERYAELYRRQPFPQPMEECGACDEPDIPELSPLQIPEEGEDEMHQLPRIQNGAELLEPLSSEEPLELPPCAHSPHPAKDPHSGFYSPAPSRGFCSSGDSGGLGLPQCSHTTVLDLDTHVVTTVESGYLHQDCPCQGAPRPALLTAPPKRKYAPAGYSYSGHGVAEEEEDVEPHFVPCKRGRYEDFCPQPLGEPTDSNNISNLISIFGSGFSGLMSRQSEAEQSLNGHLCGKQALASLGAWTRAIVAF
What are the official names of this protein?
Immediate early response gene 5-like protein.
What is the protein family that this protein belongs to?
Belongs to the IER family.