PharMolix/UniProtQA huggingface dataset:
Protein: PP1L_ENCCU
Sequence: MDIREMDLKRQEANALFKKQMIDEALEIYKTSFLEATKSVVPGTRNDLLEEQLSLLAYNISVVYYKRKNFPKSLAFGLESLKHRKSDKVLCKICAIYLRLGMLREYKEMYDQMVTRSSGPEVAFLLKRMKLSEVIVEKHLEKRVTLESLHELSKEISGGRSIPADTLESILEQGESILLGCENVVHTESSGEVLIFGDTHGQYFDVVSILNKVFDKDRMVIFNGDYVDRGSHSVENFALLLSLKILFPGRVHLTRGNHELSDINRVYGFYDEVKRKYPFSSDSVYRRFQDAFRALPISIIVNEKVFITHGGLPEAPVKVDNLQEIYRMTDTHTDELLKGLLWSDPEEILGTEESKRRAGVVFGADVTARFLERNGLDLLVRSHQAVDDGYRVHHGGKVVTIFSAPEYEGSKGPGSYLVLNPSAGEADEIVEISPLTRYKAVKFGRSDGKEVLRLLCN
What are the official names of this protein?
Probable serine/threonine-protein phosphatase ECU05_0440, PP-1G, Protein phosphatase 1C catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-1 subfamily.
Protein: HIS4_WOLSU
Sequence: MEIIPAIDLKEGQAVRLTKGLMESAKIYSDEPWRLAKSFEELGAKWLHIVDLNGAFAGEPKNLESIRKIRESCNLKIELGGGIRDEATIKRYVELGVDRIILGSVAMKNPEFVKEMASRYKIAVGIDAKEGYVAAEGWAETGKVKATELAALFREVPLDAIICTDISKDGTLEGINREFTQAIAEASGHYTIASGGLASEEEIPLLAQAKGVDGVIVGKAFYEGRIDLGTLYKRLSGCLN
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y888_STRPM
Sequence: MNIMEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIADEFGVSRQAVYDNIKRTEKILETYEMKLHMYSDYVVRSEIFDDMIAHYPHDEYLQEKISILTSIDNRE
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein M28_Spy0888.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: V_RINDR
Sequence: MAEEQAYHVNKGLECIKALRARPLDPLVVEEALAAWVETSEGQTLDRMSSDEAEADHQDISKPCFPAAGPGKSSMSRCHDQGLRGSNSCDEELGAFIGDSSMHSTEVQHYHVYDHSGEKVEGVEDADSILVQSGADDGVEVWGGDEESENSDVDSGEPDPEGSAPADWGSSPISPATRASDVETVEGDEIQKLLEDQSRIRKMTKAGKTLVVPPIPSQERPTASEKPIKKGHRREIDLIWNDGRVFIDRWCNPTCSKVTVGTVRAKCICGECPRVCEQCITDSGIENRIWYHNLADIPE
What is the function of this protein?
Plays an essential role in the inhibition of host immune response.  Prevents the establishment of cellular antiviral state by blocking interferon-alpha/beta (IFN-alpha/beta) production and signaling pathway.  Interacts with host IFIH1/MDA5 and DHX58/LGP2 to inhibit the transduction pathway involved in the activation of IFN-beta promoter, thus protecting the virus against cell antiviral state.  Blocks the type I interferon signaling pathway by interacting with host TYK2 and thereby inhibiting downstream STAT1 and STAT2 phosphorylation (By similarity).
What are the official names of this protein?
Non-structural protein V.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses V protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: GCSP_CUPMC
Sequence: MNAPLPMNAAAQGARPTLAELEARDAFAARHIGPDSAEQQHMLKVLGFESRAALIDAVVPAAIRRRDGMSLGEFTAPLTEEAALGRLRALAGKNRVLKSFIGQGYYNTLTPGVILRNIFENPAWYTAYTPYQPEISQGRLEAMLNFQQMITDLTGLDIANASMLDEGTAAAEAMTLLQRVNKHASNTFYVAEDVLPQTLEVVRTRALPLGIEVKVGPAADAAQAHAFGVLLQYPGVNGDVADYRAIAEAVHASGGRVVAAADLLALTLIAAPGEWGADVTVGNSQRFGVPLGFGGPHAGYMAVKDEFKRSMPGRLVGVTIDAQGNKAYRLALQTREQHIRREKATSNICTAQVLLAVMASMYAVYHGPQGLKRIAQRVHRLTATLAAGLKTLGHTPLNATFFDTLTLETGFNTDAFHASATARGINLRHVDATRIGISFDETASRDDVIALWEIFAHGKAVPDFDTIEASVQDGFPATLARQSAYLTHPVFNTHHAEHEMLRYLRALADKDLALDRTMIPLGSCTMKLNATSEMIPVTWPEFSNIHPFAPLDQTVGYREMIDQLEAMLCAATGYAAVSLQPNAGSQGEYAGLLIIHAYHASRGESHRDICLIPSSAHGTNPASAQMAGMKVVVVACDENGNVDLADLAKKAEQHSKNLAAIMITYPSTHGVFEQGVQQICDIVHKHGGQVYVDGANMNAMVGVAAPGQFGGDVSHLNLHKTFCIPHGGGGPGVGPVAVGAHLADFLPNQDSVGYRRDENGIGGVSAAPFGSASILPISWMYIAMMGSAGLTAATENAILTANYVARRLSPHFPVLYTGQHGLVAHECILDLRPLQKATGISNEDVAKRLMDYGFHAPTMSFPVPGTLMIEPTESEALHELDRFIDAMIAIRGEIARVEDGSFDREDNPLKHAPHTAAVVVSDKWNHKYTREEAAYPVASLRTQKYWPPVGRADNVYGDRNLFCSCVPLSEYAED
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: SCPA_STRP2
Sequence: MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVSTLQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLLGEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHTTILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELILVQEESFGDIYLMEKKEESQVPQS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: YDEO_SHIFL
Sequence: MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFNENTIKKYLQCTNIQTVTVPVPAKFLRASNVPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNSPKRVSKEYRCQRHTGMNTGNTMSALAI
What is the function of this protein?
Induces the expression of gadE.  Could also regulate the expression of other genes involved in acid resistance (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator YdeO.
Protein: MZM1_FUSV7
Sequence: MATVPALNAYRHLMRAARIAFQGDTQILSAAQVQIRNEFRQKASIDSTGASAAIQHAEEVAKVLRENVVQGKKTEEGKDTYKLRIHEHTERGDNESILTAGSGNTTGGGCCGGGGR
What is the function of this protein?
Assembly factor required for Rieske Fe-S protein RIP1 incorporation into the cytochrome b-c1 (CIII) complex.  Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.  Modulates the mitochondrial matrix zinc pool (By similarity).
What are the official names of this protein?
Mitochondrial zinc maintenance protein 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family. MZM1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: DHX16_PANTR
Sequence: MATPAGLERWVQDELHSVLGLSERHVAQFLIGTAQRCTSAEEFVQRLRDTDTLDLSGPARDFALRLWNKVPRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRKKRKHLRKKREEEEEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSRHERQELKYKRRVRDLAREYRAAGEQEKLEATNRYHMPKETRGQPARAVDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEEETIEFVRATQLQGNEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTNKGMKIACTQPRRVAAMSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKDVARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFYTKAPEADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDYIRVRKAITAGYFYHTARLTRSGYRTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKIGKTREELG
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome.  Contributes to pre-mRNA splicing after spliceosome formation and prior to the first transesterification reaction.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs.  Plays also a role in innate antiviral response by acting as a pattern recognition receptor sensing splicing signals in viral RNA.  Mechanistically, TRIM6 promotes the interaction between unanchored 'Lys-48'-polyubiquitin chains and DHX16, leading to DHX16 interaction with RIGI and ssRNA to amplify RIGI-dependent innate antiviral immune responses.
What are the official names of this protein?
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16, ATP-dependent RNA helicase #3, DEAH-box protein 16.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DEAH subfamily. DDX16/PRP8 sub-subfamily.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm.
Protein: GLO2_THEVB
Sequence: MMIYRLNALTDNYIFLLHDPQTGTAAVVDPAEPEPVLAKLAELGATLRAIFNTHHHWDHVGANCALRSRFPDIAVYGSSEDQGRIPEQTVFLKAGDRVPFGQTYFDVLFVPGHTRGHIAYYAPTTGDLFCGDTLFGGGCGRLFEGSPAQMLDSLNQLRQLPEETRVWCAHEYTQKNLSFALTVEADNPTLQERYAQVCRDRAQGKATIPSTIGLEKATNPFLRCEVRSIQIAVGATTPLQTFTRLRGKRDQY
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: YBEY_SHESW
Sequence: MSLELALDVQYATTSDWLPTEEQLMLWAKTAIGNGMDRAELTIRIVDSRESQMLNSTYRGKDKPTNVLSFPFEAPAEIELPLLGDLVICAAVVENEAREQNKTLEAHWAHMVVHGCLHLLGYDHIEDEEAEEMESLETQLIESLGFTNPYKEQ
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_MYCGE
Sequence: MAEMIEAKNLRNGQTIFGPNKEILLVLENTFNKTAMRQGIVKTKVKNLRTGAIVWLEFTGDKLEQVIIDKKKMNFLYKDGNNFVFMDQKDYSQIEINEKKLEWEKNFITEEIEVTVITYQDEILGVNLPDLVPIEVEFAEDAIQGNTANMARKKARLVTGYELDVPQFINTGDKIVIATVDGNYRERFNK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_CLOBL
Sequence: MSKKPVVLMILDGFGLTNKVDGNAVSAANKPNLDNILKKYPHTQLGASGMDVGLPEGQMGNSEVGHLNIGAGRIVYQALTKITKSISDGDFFENVALNKAIENAKKNNSTLHLLGLLSPGGVHSHIDHLKGLIKLAKEKDIKKVYIHAFLDGRDVAPSSAKEYIEDIEIYMQEIGVGEIATISGRYYAMDRDKRWERVQLCYNAIVLGKGEEANSAVEGLEKSYRDNKTDEFVLPSVVLKEGKPKAKIENKDSVVFFNFRPDRARELTRAINDKVFDGFERETLDLTYVTMTEYDSTLENVEVAFPPEHLNNTLGEYVSKNGKKQLRIAETEKYAHVTFFFNGGVEEPNEGEDRVLIPSPKVATYDMQPEMNAYEVTDKLLERLDEDKYDMVILNFANPDMVGHTGVFEAAKKAIETVDECVGKIVNKVLEKDGTAFITADHGNSEEMIDYSTGKPMTAHTTNPVPFMYVSNDSKELREGGKLADIAPTMLQLMNLPKPSEMTGNSLIK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RPOZ_AERHH
Sequence: MARVTVEDAVKQVGNRFDLVLVAARRARQIAVQGKDPLVDEENDKPTVIALREIELGLVNNQVMDTQDRYEQQEQEAAELAAVAAIAEGRG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: KATG_XANAC
Sequence: MTTEAKCPFNHAVVGTGTTNRDWWPKQLRVDLLSQHSSKSNPLDPSFNYADAFKHLDLQALKQDLHALMTDSQDWWPADFGHYGPLFVRMAWHSAGTYRIGDGRGGGGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQAISWADLMILTGNVALESMGLKTFGFAGGREDTWEPDQDLYWGRETKWLGGDERYSRGSPGVDEAHGVLVKDDDSQVPHTRDLENPLAAVQMGLIYVNPEGPDGNPDPIASARDIRDTFARMAMNDEETVALIAGGHTFGKTHGAGPADYVGAEPEAGELESQGFGWHNRYGSGKGADTITSGLEVTWTTTPAQWSNDYFDHLFGFEWELSKSPAGAHQWVAKNADAIIPDAHDASRKHRPTMLTTDLALRFDPAYEAISRRFQQHPEQFADAFARAWFKLTHRDMGPRARYLGADVPAEELVWQDPVPAVDHALVDAQDAAALKQTILASGLSVAHLVSTAWASASTFRGSDKRGGANGARIRLAPQKEWQANQPEQLAKVLATLERIQADFNAAQSGGKKISLADLVVLAGNAAVEHAAQAAGHQVTVPFAPGRTDASQEQTDVESFAVLEPVADGFRNFAKRRYAVPAEALLIDKAQLLTLTAPELTVLVGGLRVLGANVGDSKHGVFTSRPGVLSNDFFANLLDMRTEWKATSEAKEVFEGRDRSTGELRWTGTRVDLVFGSNSILRAVAEVYASADAQEKFVHDFVAAWTKVMQLDRFDLA
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: XKR7_MOUSE
Sequence: MAAKSDGAAAVAGPGPEGPAGADRGGAGGRGEAAAGIAGPGPVEAGCPGPRYELRDCCWVLCALLVFFSDGATDLWLAASYYLQGQSTYFGLTLLFVLLPSLVVQLLSFRWFVYDYSEPAGTPGPAVSTKDSDIVGAAISTKDSAVAFRTKEGSAELVPRPAPSSAGTYRRRCCRLCVWLLQTLVHLLQLGQVWRYLRALYLGLQSRWRGERLRRHFYWQMLFESADVSMLRLLETFLRSAPQLVLQLSLLVHRGREPELLTALSISASLVSLAWTLASYQKVLRDSRDDKRPLSYKGAVVQVLWHLFTIAARTLAFALFASVYKLYFGIFIVAHWCIMTFWVIQGETDFCMSKWEEIIYNMVVGIIYIFCWFNVKEGRSRRRVTLYYCIVLLENAALTGFWYSSRNFSTDFYSLILVCVVASSFALGIFFMCVYYCLLHPNGPMLGPQAPGCIFPEAPGPCGPPADAITSPPRSLPRTTGTERDGVAVGGERAGTPTLPVFQVRPGLPPTPVARPLRTEGPVIRIDLPRKKYPAWDAHFIDRRLRKTILALEYSSPATPRLQYRSMGTSQELLEYETTV
What are the official names of this protein?
XK-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the XK family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EF1A1_DICDI
Sequence: MGKEKTHINIVVIGHVDAGKSTTTGHLIYKCGGIDKRVIEKYEKEASEMGKQSFKYAWVMDKLKAERERGITIDIALWKFETSKYYFTIIDAPGHRDFIKNMITGTSQADCAVLVIASPTGEFEAGIAKNGQTREHALLAYTLGVKQMIVAINKMDEKSTNYSQARYDEIVKEVSSFIKKIGYNPEKVAFVPISGWNGDNMLERSDKMEWYKGPTLLEALDAIVEPKRPHDKPLRIPLQDVYKIGGIGTVPVGRVETGIIKPGMVVTFAPAGLSTEVKSVEMHHEQLPEARPGDNVGFNVKNVSVKEIKRGMVAGDSKNDPPQETEKFVAQVIVLNHPGQIHAGYSPVLDCHTAHIACKFTEIVDKVDRRTGAVVAKEGTAAVVLKNGDAAMVELTPSRPMCVESFTEYPPLGRFAVRDMRQTVAVGVIKSTVKKAPGKAGDKKGAAAPSKKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.  It is also an abundant actin filament bundling protein.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, 50 kDa actin-binding protein, ABP-50.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_PASMU
Sequence: MAKLYFYYSTMNAGKSTTLLQSSYNYQERDMNTLVYTAAIDDRFGVGKVTSRIGISQEAQLFHKESDLFVEIAQHLQQQPLHCILVDEAQFLTKTQVYQLSEVVDKLKIPVLCYGLRTDFQAELFEGSKYLLAWADQLEELKTICYCGRKANFVLRLNDKGEVVRDGAQIQIGGNDSYLSVCRLHYKEKIAL
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6590_BACAN
Sequence: MIFPLFGANVLMVVVKSVKNENKEPFFRRGLKNINTKECIVNILIICDSYIKIYNLYN
What are the official names of this protein?
Uncharacterized protein pXO2-67/BXB0090/GBAA_pXO2_0090.
Protein: YCF15_CAPBU
Sequence: MLLLKHGRIEILDQNTMYGWYELPKQEFLNSEQPELLLTTSKKFPLIKDGNPLENQKYACWMKLLLLSVPITNQLNN
What are the official names of this protein?
Putative uncharacterized protein ycf15, Orf77.
What is the protein family that this protein belongs to?
Belongs to the ycf15 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NRAMC_CAEEL
Sequence: MEGEMKCPIEEIREKPEMRKAQQTYEVQVEVEDTPDTTFSWRKLWAFTGPGFLMSIAYLDPGNIESDLQAGAISYFKLIWVLLVAHIMGLLLQRLAARLGVVSGKHMAEIAFSYYPKIPRLVLWMLVESAIVGSDMQEVIGTAISFYLLSNGVIPLWAGVLITICDTFTFLFLEKYGVRKFEAFFCFLITCMAITFGYEFGVSAPDAGKMFSGMFVPWCNGCDNNMVMQGVAIIGAVIMPHNFYLHSALVKSRRVDRRRAEKVTEANKYFFIESAFALFVSFIINTLVISVFAQGMYGKTNQDIRDTCYNNTHNGMPDFYKVEFPANNDAAQSDIYHAGIFLGCTFGIFALYVWAVGILAAGQSSTMTGTYAGQFAMEGFIQIKLPQWKRILITRSLAILPTLAVVIFSGGIDNISSLNDFLNCLQLIQLPFALIPVLTFVSDRNIMHEYKLASVSKVVSIVISLIILFINFYFLYSWIGSTFGYNAVSIPITIFCAIFYIIFIAYLTYYCLVAMEFISPIQTKWLAEPIYHDFDAPWLEDSENPSTKNTISDDELSMRY
What is the function of this protein?
Probable divalent metal ion transporter which regulates the uptake of several heavy metals such as Mn(2+), Al(3+) and iron (PubMed:19924247, PubMed:23106139, PubMed:19785996, PubMed:22194696).  Plays a role in modulating Al(3+)-induced dopamine (DA) neuron degeneration through the intracellular sequestration of Al(3+) (PubMed:23106139).
What are the official names of this protein?
NRAMP-like transporter smf-3, DMT-1, Divalent metal transporter smf-3.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Note=Translocates to apical cytoplasmic vesicles in intestine in response to high Mn(2+) levels (PubMed:19924247). In dopaminergic neurons, localizes to cytoplasmic vesicles (PubMed:23106139).
Protein: TILS_STAEQ
Sequence: MNIKTDGWSKKAHIVVAVSTGIDSMSLLYSLLNDYQHTYRKLTCVHVNHGLREQSYEEEAFLREYCHQHHIDIYIKRLDLSDIVADGNSIQQEARQRRYEWFGDIIAQLRADVLLTAHHLDDQFETIIYRLFTGRSTRNSLGMTYESYFNQYKVYRPMLNLKKTEILAYQYANQIPYYEDMSNQDRKYVRNDIRQRIIPAINENPHLNAHQLLKLKDWHDIELQSLKEQAETFINNEVSKSKYLTYSFSRTAFNELNVNIKSVVMDLLFEKLDCHLAMPQHAYDEWFEQIRNDKSQFNIHVTDEWIIQIAYDKLIIMAKSEMDQYILDRICIRKPGTYEFNDYQIDIHPDLPQQLYPLTVRVRQNGDVYKLNGQKGHKKVSRLFIDKKVTLAERQRIPLIINQENAVLAIGDLYVKENFKEFILISNNGDEL
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_RAT
Sequence: MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIDRCLERGKSSGRSDDNRESLEKRIQTYLESTKPIIDLYEEMGKVKKIDASKSVDEVFGDVMKIFDKEG
What is the function of this protein?
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP.  Plays an important role in de novo pyrimidine nucleotide biosynthesis.  Has preference for UMP and CMP as phosphate acceptors.  Also displays broad nucleoside diphosphate kinase activity.
What are the official names of this protein?
UMP-CMP kinase, Deoxycytidylate kinase, CK, dCMP kinase, Nucleoside-diphosphate kinase, Uridine monophosphate/cytidine monophosphate kinase, UMP/CMP kinase, UMP/CMPK.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly nuclear.
Protein: RUVA_SACEN
Sequence: MIASVRGPVLSVGLDHAVIEVGGVGMAVHATPATLAGLRRGEEARLWTSLIVREDSLTLYGFADAEARDLFGLLQTASGVGPRLALATLAVLAPDQLCHALSDGNITTLTQVPGVGKKSAERLILELRDKVGTVAGTAGAGAQAPDRGRVRSEVSEALVGLGFSAKQAEQSVEAVLAADGPVSDTSAVLRKALAALGPKK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: RHO_BUCBP
Sequence: MNLTALKNIPVSELIFLGDNAGLENLARMRKQDIIFSILKQHAKSGEDIFGDGVLEILQDGFGFLRSSDSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNKVNYDKPENARSKILFENLTPLHANSRLRMERGNGSTEDLTARVLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMRRLVKGEVVASTFDEPSSRHVQVSEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEEFKGTGNMELPLSRKIAEKRVFPAIDYNRSGTRKEELLTKSDELQKMWILRKIIHPMSEIDAMEFLINKLAMTKTNNEFFDMMKRS
What is the function of this protein?
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
What are the official names of this protein?
Transcription termination factor Rho, ATP-dependent helicase Rho.
What is the protein family that this protein belongs to?
Belongs to the Rho family.
Protein: WHIA_MYCSS
Sequence: MAMTAEVKDELSRLVVNSVSARRAEVASLLRFAGGLHIVSGRVVVEAEVDLGIIARRLRKDIYDLYGYNAVVHMLSASGIRKGTRYVVRVAKDGEALARQTGLLDLRGRPVRGLPAQVVGGSVADAEAAWRGAFLAHGSLTEPGRSSALEVSCPGPEAALALVGAARRLGVSAKAREVRGSDRVVVRDGEAIGALLTRMGAQDTRLTWEERRMRREVRATANRLANFDDANLRRSARAAVAAAARVERALEILGDTVPDHLASAGKLRVEHRQASLEELGRLADPPMTKDAVAGRIRRLLSMADRKAKQDGIPDTESAVTPDLLEDA
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: ADH2_DROMU
Sequence: MVIANKNIIFVAGLGGIGFDTSREIVKSGPKNLVILDRIENPAAIAELKALNPKVTVTFYPYDVTVSVAETTKLLKTIFDKLKTVDLLINGAGILDDYQIERTIAVNFTGTVNTTTAIMSFWDKRKGGPGGIIANICSVTGFNAIYQVPVYSASKAAALSFTNSLAKLAPITGVTAYSINPGITKTTLVHKFNSWLDVEPRVAELLLEHPTQTTLQCAQNFVKAIEANQNGAIWKLDLGTLEAIEWTKHWDSHI
What are the official names of this protein?
Alcohol dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.