PharMolix/UniProtQA huggingface dataset:
Protein: SPCS_METKA
Sequence: MRGLIPDHMLERGRTVLDSYREPVERLLSERRMPEEGWPDDVIATFLWELSRMDTDKDPKAARIGEREARVASRLAEESVFGFCHGVGRSGTLVDPQPKAPGASIMYALTNRLVTDFLRRLGFRIEGAFVVPGATGLSIALCLSALGEGEEVIYPYAAHKSPIKAVRLAGFGMRVVDTEIEGDRIVVDPGDVEEALERSESPAAVLSTLTFFPPRSSDPLPEIAELCEEYGVPHVVNAAYGIQHEQYRDLLNRAIKRGRVDVVVSSTDKNLLTPVGGGIVYAPDEETLREVSRAYPGRASAAPVAHALISLLSLGMKGYRRLMRRQKECKALLDELLEDLEARRDDVRVLDVDNPIASAVAVEGHDPVDLAARLYVRRVTGPRGVRADDPFGTSRLRGYHSNYITINAAIGVREEDVKTAVERLERELEGE
What is the function of this protein?
Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
O-phosphoseryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase, Sep-tRNA:Sec-tRNA synthase, SepSecS.
What is the protein family that this protein belongs to?
Belongs to the SepSecS family.
Protein: MNME_BACTN
Sequence: MNQDTICAIATAQGGAIGSIRVSGPEAISITSRIFQPAKAGKLLSEQKPYTLTFGRIYNGEEVIDEVLVSLFRAPHSYTGEDSTEITCHGSSYILQQVMQLLIKNGCRMAQPGEYTQRAFLNGKMDLSQAEAVADLIASSSAATHRLAMSQMRGGFSKELTDLRSKLLNFTSMIELELDFSEEDVEFADRSALRKLADEIEQVISRLVHSFNVGNAIKNGVPVAIIGETNAGKSTLLNVLLNEDKAIVSDIHGTTRDVIEDTINIGGITFRFIDTAGIRETNDTIESLGIERTFQKLDQAEIVLWMVDSSDASSQIKQLSEKIIPRCEEKQLIVVFNKADLIEEMQKEELSALLKNFPKEYTKSIFISAKERRQTDELQKMLINAAHLPTVTQNDIIVTNVRHYEALSKALDAIHRVQDGLDSHISGDFLSQDIRECIFFISDIAGEVTNDMVLQNIFQHFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERG9_GANLU
Sequence: MGATSMLTLLLTHPFEFRVLIQYKLWHEPKRDITQVSEHPTSGWDRPTMRRCWEFLDQTSRSFSGVIKEVEGDLARVICLFYLVLRGLDTIEDDMTLPDEKKQPILRQFHKLAVKPGWTFDECGPKEKDRQLLVEWTVVSEELNRLDACYRDIIIDIAEKMQTGMADYAHKAATTNSIYIGTVDEYNLYCHYVAGLVGEGLTRFWAASGKEAEWLGDQLELTNAMGLMLQKTNIIRDFREDAEERRFFWPREIWGRDAYGKAVGRANGFREMHELYERGNEKQALWVQSGMVVDVLGHATDSLDYLRLLTKQSIFCFCAIPQTMAMATLSLCFMNYDMFHNHIKIRRAEAASLIMRSTNPRDVAYIFRDYARKMHARALPEDPSFLRLSVACGKIEQWCERHYPSFVRLQQVSGGGIVFDPSDARTKVVEAAQARDNELAREKRLAELRDKTGKLERKLRWSQAPSS
What is the function of this protein?
Squalene synthase; part of the third module of ergosterol biosynthesis pathway that includes the late steps of the pathway (By similarity).  The third module or late pathway involves the ergosterol synthesis itself through consecutive reactions that mainly occur in the endoplasmic reticulum (ER) membrane (By similarity).  Firstly, the squalene synthase SQS catalyzes the condensation of 2 farnesyl pyrophosphate moieties to form squalene, which is the precursor of all steroids (PubMed:18051320).  Secondly, the squalene epoxidase catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, which is considered to be a rate-limiting enzyme in steroid biosynthesis (By similarity).  Then, the lanosterol synthase LS catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol core (PubMed:20460708).  In the next steps, lanosterol is transformed to ergosterol via a complex process involving various demethylation, reduction and desaturation reactions (By similarity).  Lanosterol is also an intermediate in the biosynthesis of triterpenes such as ganoderic acids (GA), a group of highly oxygenated lanostane-type triterpenoids which are well recognized as a main group of unique bioactive compounds in the medicinal mushroom Ganoderma lucidum (Probable).
What are the official names of this protein?
Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
Protein: RSMJ_COXBR
Sequence: MNDTLAITYSTPARLSEAEKLARQMKLPLVSLNSTDYSFLLVFTPAHLELRSTGTKAPGPLYVDFLKGATAHRRLFGGGRSQLIVRAVGLKSHPHPTILDLTAGLGRDAFVLANLGCDVLMIERNPVIALLLRDGLERAQSVEWFKSLKLELIEIDAQIYLSTLKKQFDVIYMDPMYPIRKKSALVKKEMRILRRLVGADDDAPQLLALALKKAKHRVVIKRPRLSNPLPGPAPDVVYEGKSSRFDVYLLKPSS
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL15_DEHMC
Sequence: MRLHELSPAPGSRKDRKRVGRGDAGRGNYSGRGMKGQKARSGGATRPGFEGGQLPIYLRLPRKRGFFNPFRIKYAVVNIEQLNMFEAGTEVTPETLLAAGLIRNFVKPVKILSSGHIDRALEVSAHKFSQAAKAQIEAAGGKVQEIDYAAEIE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RS6_YERE8
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYSATITNAAGTIHRLEDWGRRQLAYPINKLHKAHYVLLNVEAPQEAIDELETNFRFNDAVIRSMVMRVKHAVTEASPMVKAKDERRERHDFASEANDDSEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: RL35_MYCA1
Sequence: MPKAKTHSGASKRFRRTGTGKIVRQKTNRRHLLEHKPTTRTRRLEGRTTVSANDTKRVNSLLNG
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: GLGB_KLEP7
Sequence: MSNHIDRDVINALIAGHFADPFSVLGMHRTDAGLEVRALLPDATDVWVIEPKTGRKVGKLECLDSRGFFSGVLPRRKNAFRYQLAVTWHGQQNLIDDPYRFGPLLQDLDVWLLSEGTHLRPYETLGAHAATMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRFRKESGIWELFVPGAHNGQLYKFELIDAHGNLRVKADPYAFESQMRPESASLICDLPPKVEQPADRRAANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPVNEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFINAAHAAGLNVILDWVPGHFPADDFALASFDGTSLYEHSDPREGYHQDWNTLIYNYGRREVSNYLVGNALYWIERFGIDALRVDAVASMIYRDYSRKAGEWIPNEYGGRENLEAIEFLRNTNRILGEQTPGAVTMAEESTDFAGVTRPPAGGGLGFWFKWNLGWMHDTLDYMKLDPVHRRYHHDKMTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWLFAFPGKKLLFMGNEFAQGREWNHDVSLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKALHELDFDPYGFEWLVVDDHERSVFVFVRRDRAGNEIIVASNFTPVPRHDYRFGINQPGRWREALNTDSMHYHGSNQGNGGVVESDAIASHGREHSLSLTLPPLATIWLVREAQ
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: ACY2_PIG
Sequence: MTSCQVAEDPIKKVAIFGGTHGNELTGVFLVKHWLENNTEIQRTGLEVKPFITNPRAVEKCTRYIDCDLNRVFDPENLGKRMSEDLPYEVRRAQEISRLFGPKDSEDSYDIIFDLHNTTSNMGCTLILEDSRNDFLIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTRSIAKYPVGIEVGPQPQGVLRADILDQMRKMIKHALDFIHNFNEGKEFPPCAIEVYKIMEKVDYPRNESGEIAAIIHPKLQDQDWKPLHPGDPVFLTLDGKTIPLGGDCTVYPVFVNEAAYYEKKEAFAKTTKLTLNAKGIHSSLH
What is the function of this protein?
Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate.  NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter (By similarity).
What are the official names of this protein?
Aspartoacylase, Aminoacylase-2, ACY-2.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL5_NITEU
Sequence: MARLLEYYRDTVTKELTQKFNYKTVMEVPKITKITLNMGVGEASTDKKIIENAVSDLEKISAQKPVVTKARKSIATFKVRQGYPVGCKVTLRGVKMYEFLDRLVNVAIPRIRDFRGIQVKGFDGRGNFNMGIKEQIIFPEIDYDKIDKVRGLNITVTTTAKTDQEARALLSAFKFPFKN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: BIPA_ECOL6
Sequence: MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMDSNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDFPIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREIDGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRGKLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLEQALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD
What is the function of this protein?
A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation.  Binds GTP and analogs.  Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
What are the official names of this protein?
50S ribosomal subunit assembly factor BipA, GTP-binding protein BipA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=Binds to ribosomes.
Protein: COAX_EHRCR
Sequence: MLIAIDIGNTNIKLAICANNKIIKRITISSQSRRTADEYFIYLNSTMNQLNLDYKNINNIIISSVVPSITKPIIELSQNYFNIDPTILSNHHADIFNIKISLQNKVLGSDRLADIIAASSLYPHKDLLIIGMGTATVFNLLNKDKCIYGQAIAPGAHILAKSMRQYTALLPEVLISKQDKVIHDNIYHAMESGIYWGYITMINGMIEKIIKEEEKDLYIIATGGNSNLFFNHKTAIHNIEVDLTIKGLIQLHTVLS
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC6_SYNY3
Sequence: MFKLFNQASRIFFGIALPCLIFLGGIFSLGNTALAADLAHGKAIFAGNCAACHNGGLNAINPSKTLKMADLEANGKNSVAAIVAQITNGNGAMPGFKGRISDSDMEDVAAYVLDQAEKGW
What is the function of this protein?
Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis.
What are the official names of this protein?
Cytochrome c6, Cytochrome c-553, Cytochrome c553, Soluble cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: Y2419_BURA4
Sequence: MLSPCLAVPATECRDPADAPAAPARHTGPARPRKRRPRNWKPHLPRERLLERGPAALTDAELIALLLGTGGGGRDVFASARALLARFGDSLRDMLDAEPDVFATHPGIGTARSAVLIAVTEIARRALVEKARERLQIDSPGAVEDYLRLRIGTRPHEVFVTLYLDARHGLIDVEESARGSLTRMAVYPREIVRRALVLNAAALIIAHNHPSGAVQPSAEDRRLTRVLHEALALIDAKLLDHVVVGTADTFSFARAGWL
What are the official names of this protein?
UPF0758 protein BamMC406_2419.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: NS2A_CVHOC
Sequence: MAVAYADKPNHFINFPLTHFQGFVLNYKGLQFQILDEGVDCKIQTAPHISLTMLDIQPEDYKSVDVAIQEVIDDMHWGDGFQIKFENPHILGRCIVLDVKGVEELHDDLVNYIRDKGCVADQSRKWIGHCTIAQLTDAALSIKENVDFINSMQFNYKITINPSSPARLEIVKLGAEKKDGFYETIVSHWMGIRFEYTSPTDKLAMIMGYCCLDVVRKELEEGDLPENDDDAWFKLSYHYENNSWFFRHVYRKSFHFRKACQNLDCNCLGFYESPVEED
What are the official names of this protein?
Non-structural protein 2a, ns2a, 32 kDa accessory protein, 32 kDa non-structural protein, ns2.
What is the protein family that this protein belongs to?
Belongs to the coronaviruses ns2a protein family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: DHR25_ORYSJ
Sequence: MAEHATGVYGHPYPRVDQYGNPVPPVDQYGNPVPDEPAPRDTAAGYVAPPDPAVSTGDYGLAGAEAPHPHESAVMSGAAAAAVAPGGEAYTRDGGGVVPPAGEKTFAYEGTVSAAGVTGASGQLQPTTREEGHTTLGETLRRSGKSSSSSSSSSEDDGQGGRRKKKSIKEKIKEKLPGSHKQEEQKQAGHTAPAAGTGTGTGTHAAGKHEKKGIVEKIKEKLPGHGHH
What are the official names of this protein?
Dehydrin Rab25, Drought-resistant protein 1, rDRP1.
What is the protein family that this protein belongs to?
Belongs to the plant dehydrin family.
Protein: OPGB_SALCH
Sequence: MSELLSVALFLASVLIYAWKAGRNTWWFAATLTVLGLFVILNITLYASDYFTGDGINDAVLYTLTNSLTGAGVGKYILPGIGIALALVAVFGALGWVLRRRRHHPHHVGYSLLALLLALGSVDASPAFRQITELVKSQMRDGDPDFAVYYKEPAKTIPNPKLNLVYIYGESLERTYFDNDAFPNLTPELGALKNEGLDFSHTMQLPGTDYTIAGMVASQCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKSHGFDNLYGAEELKTVVADPSYRNDWGFYDDTVLDEAWKKFEALSRSGQRFSLFTLTVDTHHPDGFISRTCNRKRYDYDGKPNQSFSAVSCSQENIAEFINKIKASPWFKDTVIVVSSDHLAMNNTAWKYLNKQDRNNLFFILRGDKPQQETLAVKRNTMDNGATVLDILGGDNFIGLGRNSLSGQSLSEVFLNVKEKVLAMKPDIIRLWNFPKEIKDFTVDRDKNMIAFSGSHFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWIDRCYKMAQLWAPALALSTDWCVSQGQLGGQQTVQHVDKAQWQGKTAFKDTMIDMERYKGNVDTLKIVDNDIRYKADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKAPLPKKFDLVITAKAFGDNAERPIPVRVGNEEQTLVLGHDVSTITLHFNNPTDANTLVIAPPAPVSTNEGNILGHSPRKLGIGMVEIKVVNVEG
What is the function of this protein?
Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones.
What are the official names of this protein?
Phosphoglycerol transferase I, Phosphatidylglycerol--membrane-oligosaccharide glycerophosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the OpgB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SECD_MYCTO
Sequence: MASSSAPVHPARYLSVFLVMLIGIYLLVFFTGDKHTAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQIISARVNGLGVSGSEVVVDGDNLVITVPGNDGSEARNLGQTARLYIRPVLNSMPAQPAAEEPQPAPSAEPQPPGQPAAPPPAQSGAPASPQPGAQPRPYPQDPAPSPNPTSPASPPPAPPAEAPATDPRKDLAERIAQEKKLRQSTNQYMQMVALQFQATRCESDDILAGNDDPKLPLVTCSTDHKTAYLLAPSIISGDQIQNATSGMDQRGIGYVVDLQFKGPAANIWADYTAAHIGTQTAFTLDSQVVSAPQIQEAIPGGRTQISGGDPPFTAATARQLANVLKYGSLPLSFEPSEAQTVSATLGLSSLRAGMIAGAIGLLLVLVYSLLYYRVLGLLTALSLVASGSMVFAILVLLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRSFRSAVPRGWARARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSSLLAKPAYNGLGAVQQVARERRAMARTGRG
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
What are the official names of this protein?
Protein translocase subunit SecD.
What is the protein family that this protein belongs to?
Belongs to the SecD/SecF family. SecD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATP6_KLEP7
Sequence: MTPQDYIGHHLNNLQLDLRTFSLVDPHNHTATFWTLNIDSMFFSVVLGLLFLAMFRSVAKKATSGVPGKFQTFIEMIIGFVHGSVKDMYHGKSKVIAPLALTVFVWVFLMNLMDLLPIDLLPYIGEHIFGLPALRVVPSADVNITLSMALGVFILIIFYSIKMKGVGGFVKELTMQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWVLNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS8_CHLP8
Sequence: MPVTDSIADFITRIRNAGSAKNKTTDIPYTRVRENLSKLLVEKGYIQNYTVIKTEADKFPFIRVELKYTADGRHAIKEISRVSSPGRRVYQGKDIKRYLGGLGLFILSTSKGILTDKEAREQNVGGEVLFRIY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RL34_VICPA
Sequence: MVQRLTYRRRLSYNTASNKTRLSRTPGQQDRLPLHQEGRESTYIRMWRVPRQTARGPCCETQVLMRLSKTKKHVSRAYGGSMCAKCVRDRIKRAFLIEEQKIVVKVLKAQAQSQKAK
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm. Endoplasmic reticulum. Note=Detected on cytosolic polysomes (By similarity). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity).
Protein: CM3A_CONKI
Sequence: KRNGCCNCSSKWCRDHSRCCGR
What is the function of this protein?
Mu-conotoxin KIIIB-P2: This toxin potently blocks Nav1. 2/SCN2A (Kd=26 nM).  In addition, this toxin may also inhibit other sodium channels, as does Mu-conotoxin KIIIA-P1.
What are the official names of this protein?
Mu-conotoxin KIIIB.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LPRG_MYCTU
Sequence: MRTPRRHCRRIAVLAAVSIAATVVAGCSSGSKPSGGPLPDAKPLVEEATAQTKALKSAHMVLTVNGKIPGLSLKTLSGDLTTNPTAATGNVKLTLGGSDIDADFVVFDGILYATLTPNQWSDFGPAADIYDPAQVLNPDTGLANVLANFADAKAEGRDTINGQNTIRISGKVSAQAVNQIAPPFNATQPVPATVWIQETGDHQLAQAQLDRGSGNSVQMTLSKWGEKVQVTKPPVS
What is the function of this protein?
A host TLR2 agonist (toll-like receptor), shown experimentally for human and mouse (PubMed:19362712).  Inhibits primary human macrophage MHC-II Ag processing via TLR2 (PubMed:15294983).  Both lipidated and nonlipidated protein act as TLR2 agonists in antigen-presenting cells, although lipidated protein is more efficient (PubMed:20694006).  In resting human CD4+ T-cells lipidated but not nonlipidated protein is a costimulatory ligand (with anti-CD3 and anti-CD28) for T-cell proliferation and IFN-gamma and IL-2 production, leading to increased expression of early T-cell activation markers, TLR2 and NFKB3 phosphorylation (PubMed:21078852).  Human CD4+ T-cells use TLR1/TLR2 heterodimers to respond to this and probably other mycobacterial lipoproteins (PubMed:21078852).  Able to stimulate proliferation of CD4+ T-cells derived from a human leprosy patient following protein processing/presentation by MHC class II molecules in peripheral blood mononuclear cells (PubMed:18424702).  Requires both host TLR1 and TLR2 as coreceptors to elicit host response in mouse, although TLR6 may play a redundant role, has a partial requirement for CD14 as an accessory receptor (PubMed:19362712).
What are the official names of this protein?
Lipoarabinomannan carrier protein LprG, 27 kDa lipoprotein, Antigen P27, Lipoprotein LprG, Triacylated glycolipid carrier LprG, Triacylglyceride transfer protein LprG.
What is the protein family that this protein belongs to?
Belongs to the LppX/LprAFG lipoprotein family.
What are the subcellular locations of this protein?
Cell inner membrane; Lipid- anchor. Secreted, cell wall. Secreted. Cell surface. Note=Present in extracytoplasmic vesicles (PubMed:21364279). Immunoelectron microscopy indicates this protein is close to the cell surface (PubMed:25041568).
Protein: MURB_OLEA2
Sequence: MKPVILSGPVLKERTTLRLGGQALAEVRLDDMHAFDGLPRVLERLGGTPAVLGRGSNILARDGELPLVIINPALKAEPEAWADPQAEDRVLVRVAAGVRLPVLLGRLAAQGLSGLEGLAGVPGTVGGAVAMNAGSYGNDMGSVLSSVEIFSAGTGMICVPRSQCRCEYRHFSVPAAGGWFVVAAVTLQLRRSTATAVRDAMRSNALLKKKTQPVTEHSAGCVFKNPADGISAGRLLDQCGFRGRGKGGMAFSSLHANFLVNKAQGTSDDAMDLINDARHAVERATGHYLELEVKIWPWQ
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CREL2_DANRE
Sequence: MLLSCSIFRLFCIILLLQLGSIYTKDFTALCSTCRQLVDDFDKGLEKTAKQNFGGGNTAWEERKLSKYETSEIRLTEILEGLCQSSNFECSHMLEENEEHLEAWWFKRKTKHPDLFKWFCIETIKVCCPKGSFGPDCNTCIGGADRPCHGNGKCDGDGTRAGNGKCSCDEGYDGEFCLDCSDGYFNSLRNDTFFLCKECHESCVGCSGGTNQHCKECRNGWVKDQEGSCIDINECIKDPAPCSDDQYCLNTDGSFSCKACDIRCTGCKGDGASSCLNCADGYKDEEGTCTDIDECTEDPASCSDNQHCLNTDGSFSCEEKVPAFNSEGAKTGDSPEKHEDL
What is the function of this protein?
Possible role in neuronal acetylcholine receptor transport.
What are the official names of this protein?
Cysteine-rich with EGF-like domain protein 2.
What is the protein family that this protein belongs to?
Belongs to the CRELD family.
What are the subcellular locations of this protein?
Secreted. Endoplasmic reticulum.
Protein: OPDA_HAEIN
Sequence: MSMSNPLLNIQGLPPFSQIKPEHIRPAVEKLIQDCRNTIEQVLKQPHFTWENFILPLTETNDRLNRAWSPVSHLNSVKNSTELREAYQTCLPLLSEYSTWVGQHKGLYNAYLALKNSAEFADYSIAQKKAIENSLRDFELSGIGLSEEKQQRYGEIVARLSELNSQFSNNVLDATMGWEKLIENEAELAGLPESALQAAQQSAESKGLKGYRFTLEIPSYLPVMTYCENRALREEMYRAYATRASEQGPNAGKWDNSKVMEEILTLRVELAKLLGFNTYTELSLATKMAENPQQVLDFLDHLAERAKPQGEKELQELKGYCEKEFGVTELAPWDIGFYSEKQKQHLYAINDEELRPYFPENRVISGLFELIKRIFNIRAVERKGVDTWHKDVRFFDLIDENDQLRGSFYLDLYAREHKRGGAWMDDCIGRKRKLDGSIETPVAYLTCNFNAPIGNKPALFTHNEVTTLFHEFGHGIHHMLTQIDVSDVAGINGVPWDAVELPSQFMENWCWEEEALAFISGHYETGEPLPKEKLTQLLKAKNFQAAMFILRQLEFGIFDFRLHHTFDAEKTNQILDTLKSVKSQVAVIKGVDWARAPHSFSHIFAGGYAAGYYSYLWAEVLSADAYSRFEEEGIFNPITGKSFLDEILTRGGSEEPMELFKRFRGREPQLDALLRHKGIMN
What is the function of this protein?
May play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins.  Can cleave N-acetyl-L-Ala(4) (By similarity).
What are the official names of this protein?
Oligopeptidase A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M3 family.
Protein: SECB_YERPG
Sequence: MSEQNNTEMAFQIQRIYTKDISFEAPNAPQVFQQDWQPEVKLDLDTASSQLAEDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSVAGIEGTQLAHCLGAYCPNILFPYARECITSLVSRGTFPQLNLAPVNFDALFMNYLQQQAEGEVEGVEQRQDA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.