PharMolix/UniProtQA huggingface dataset:
Protein: KHSE_SULIK
Sequence: MECKRARAYSSSANLGSGFDILSMAHTAFFDTVEICVETKNSENIVIESNSKIPLEPNRNSATYPLVRIMEERGIKASLRVKVIKGIPEGLGLGSSGASATAAVMAFSSLFNLNLSKEDLVRYAMYGEIASSGSPHPDNVAASVFGGVVSVVSVNPVKVVEIPLNYSFNILLFVPLNVHIEEKTKKAREMVPKTVKLSDYINNSRYISSLLIGFVKGERDLIRLGLNDEIVEKARLPLFPYYPKIKEIAIKYDAVGSCVSGAGPSILVLTDKMTDENKIAEEGTKTCNEFNVECEVIKAKIAGGVEVERRN
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANXA8_RABIT
Sequence: MAWWKAWVEQEGVTVKGSPHFNPVPDAETLYKAMKGIGTNEQAIIDVLTRRSSAQRQQIAKSFKAQFGSDLTETLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLQEIMKAYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVTGFVDPGLALQDAQDLYAAGEKICGTDEMKFITILCTRSARHLMRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTIVKCTRNLHCYFAERLHYAMKGAGTLDGTLIRNIVSRSEIDLNLIKGHYKKMYGKTLSSMIMEDTSGDYKNALLSLVGSDP
What is the function of this protein?
This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
What are the official names of this protein?
Annexin A8, Annexin VIII, Annexin-8.
What is the protein family that this protein belongs to?
Belongs to the annexin family.
Protein: RBFA_HELPH
Sequence: MNAHKERLESNLLELLQEALAGLNDSELNSLSVTKVECSKGKHHALVFVLSSDHKILSKLKKAEGLIRQFVLQASGWFKCPKLSFVSDNSLEKQLRLDAIFNEIAKGRDND
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_SALPA
Sequence: MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFDGVTTGTSIGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQMGDIPLEIKDWRQVELNPFFCPDADKLDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAVKGVEIGEGFNVVALRGSQNRDEITAQGFQSNHAGGILGGISSGQHIVAHMALKPTSSITVPGRTINRMGEEVEMITKGRHDPCVGIRAVPIAEAMLAIVLMDHLLRHRAQNADVKTEIPRW
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ARGA_YERPN
Sequence: MKERSTELVQGFRHSVPYINAHRGKTFVVMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDSNLADHNYEPIYHKHTRVTDARTLEMVKQAAGLLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEEAIHRQLDNGAIVLLGPVAVSVTGESFNLTSEEVATQLAIKLKAEKMIGFCSSQGVTDSEGNIISELFPNDAQKRIEDLEQDGDYNSGTVRFLRGAVKACRSGVRRSHLLSYQEDGALIQELFSRDGIGTQIVMESAEQVRRATINDIGGILELIRPLEQQGILVRRSREQLEMEIDKFTIIERDNLTIACAALYPFPDEHIGEMACVAVHPDYRSSSRGEMLLNRITNQARQMGLKKLFVLTTRSIHWFQERGFTPAEVDVLPIQKQELYNYQRRSKILLADL
What are the official names of this protein?
Amino-acid acetyltransferase, N-acetylglutamate synthase, AGS, NAGS.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. ArgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_PROM3
Sequence: MARRYLFEFEKPLVELEQQIEQIRELARDSEVDVSQQLLQLETLAARRREEIFQALTPAEKIQVARHPHRPSTLDFIQMFCDDWVELHGDRRGSDDQALVGGVGRIGKRSVLLIGHQKGRDTKENVARNFGMATPGGYRKALRLMDHADRFRLPILTFIDTPGAYAGLLAEEQGQGEAIAVNLREMFRLRVPVIATVIGEGGSGGALGIGVADRLLMFEHSVYTVASPEACASILWRDAAKAPEAAAALKITGPDLLSLGVVDEVLPEPAGGNNWAPLQAGEVLREAIERHLDDLLGLKVNQLRESRYRKFRAMGRVLDPSSSETGLPA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_YARLI
Sequence: MTRYSVQSVDPTKTASARGAYLRTSFKNTYEVAGAIRGWNLQKALAYLDQVTDHKRAIPFRKHAGSIGRTGQGKEFGVTKARWPVKSIKFVQDLLQNAQANAETKGLDKETLVISHIQVNQAPKQRRRTYRAHGRINAYQSSPSHIELILSEPAEEIAKAKETSLAHISSRQRGRIAAQKRISA
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PCH13_PENRB
Sequence: MGFLKLLSTSLATLAVVNAGKLLTANDGDEVVPSSYIVVMNDGVSTAQFETHRNWAANVHARTRSLKGGESGPGKHFDINGMKGYSASFDDRTVKDIASDPTVKYVEPDMVVNATANVVQRNAPSWGLSRISSKKSGATDYVYDSTAGEGIVIYGVDTGIDIGHADFGGRAEWGTNTADNDDTDGNGHGTHTASTAAGSKFGVAKKASVVAVKVLGADGSGTNSQVIAGMDWAVKDSKSRGATGKSVMNMSLGGAYSRAMNDAAANVVRSGVFLSVAAGNEAQDASNSSPASAPNVCTIAASTNSDGSASFTNFGSVVDLYAPGKDITAAYPGGGSKTLSGTSMAAPHVAGAAAYLMALEGVTSDKACARIVELAISSISSAPSGTTSKLLYNGINAQ
What is the function of this protein?
Serine protease (PubMed:11893850, PubMed:16436150).  Hydrolyzes casein, gelatin and human collagen type IV, but not elastin in vitro (PubMed:16436150).  Hydrolyzes OCLN of the human lung epithelial cells at 202-Gln-|-Ser-203 and Gln-211-|-Ile-212 (PubMed:16436150).
What are the official names of this protein?
Subtilisin-like serine protease Pen ch 13, Alkaline serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: SUCC_XANAC
Sequence: MNFHEYQSKQLLAEYGIPVPAGKVAATPDEAVEVANSLGNGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDETEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: DPCKG_THEPD
Sequence: MSSSPAARRELSYSWGYLFFDEPPLSVEKAWRLVQSSRFGKTLILVGDVVSKSFRERGLGDFFIVDGHTRRNLKVEDLPGKAEAFTCKNRPGEISRECYELLRNLLTSAIGRGKKIVVYVEGEEDLLSLVALLYCPLNDSWVIYGNFRGYLEVIPCTSFFRSVAENLLVKHFEKD
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: P2RX1_RAT
Sequence: MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSDLISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIVTPQQTQGHCAENPEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKIQHPLCPVFNLGYVVRESGQDFRSLAEKGGVVGITIDWKCDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQNGTNRRHLFKVFGIHFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGEGEHDPVATSSTLGLQENMRTS
What is the function of this protein?
Ligand-gated ion channel with relatively high calcium permeability.  Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle.  Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death.
What are the official names of this protein?
P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor, RP-2 protein.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: JANB_DROME
Sequence: MKMFKSLRLLPHIVSPFQKCYSTDLISLVGVPRVKITKGQNRYLLVNIHTHGFTKYGRVIVRGADVDNHLAVFDSILEELEPEGICAKILGGGRILNEAENKKIKIYGTSRTFGGADHTRTRNILQAWTTYKDFKITVKQ
What is the function of this protein?
JanA and janB regulate somatic sex differentiation.
What are the official names of this protein?
Sex-regulated protein janus-B.
What is the protein family that this protein belongs to?
Belongs to the janus family.
Protein: UGPC_YERPS
Sequence: MACLKLQAVTKSYDGVTPVIKQIDLDVADGEFIVMVGPSGCGKSTLLRMVAGLERTTTGDIYIGDQRVTDLEPKDRGIAMVFQNYALYPHMNVFDNMAYGLKIRGFGKEQIRQRVDEAARILELQPLLKRKPRELSGGQRQRVAMGRAIVREPAVFLFDEPLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVIVMNKGVAEQIGTPSEVYKRPASLFVASFIGSPAMNLLDGTVSPDGRTFILSDGLTLPLEIPQPQWGGRRLTLGIRPEHIQQTTSAQGVPMNLLTLELLGADNLAHGLWGGQSIIARLSHEEMPVAGSTLHLYLPPAALHFFDTDSGLRIEP
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
sn-glycerol-3-phosphate import ATP-binding protein UgpC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. sn-glycerol-3-phosphate importer (TC 3.A.1.1.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CCN3_MOUSE
Sequence: MSLFLRKRCLCLGFLLFHLLSQVSASLRCPSRCPPKCPSISPTCAPGVRSVLDGCSCCPVCARQRGESCSEMRPCDQSSGLYCDRSADPNNQTGICMVPEGDNCVFDGVIYRNGEKFEPNCQYFCTCRDGQIGCLPRCQLDVLLPGPDCPAPRKVAVPGECCEKWTCGSDEQGTQGTLGGLALPAYRPEATVGVEVSDSSINCIEQTTEWSACSKSCGMGVSTRVTNRNRQCEMVKQTRLCIVRPCEQEPEEVTDKKGKKCLRTKKSLKAIHLQFENCTSLYTYKPRFCGVCSDGRCCTPHNTKTIQVEFQCLPGEIIKKPVMVIGTCTCYSNCPQNNEAFLQDLELKTSRGEI
What is the function of this protein?
Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival.  Acts by binding to integrins or membrane receptors such as NOTCH1.  Essential regulator of hematopoietic stem and progenitor cell function.  Inhibits myogenic differentiation through the activation of Notch-signaling pathway.  Inhibits vascular smooth muscle cells proliferation by increasing expression of cell-cycle regulators such as CDKN2B or CDKN1A independently of TGFB1 signaling.  Ligand of integrins ITGAV:ITGB3 and ITGA5:ITGB1, acts directly upon endothelial cells to stimulate pro-angiogenic activities and induces angiogenesis.  In endothelial cells, supports cell adhesion, induces directed cell migration (chemotaxis) and promotes cell survival.  Also plays a role in cutaneous wound healing acting as integrin receptor ligand.  Supports skin fibroblast adhesion through ITGA5:ITGB1 and ITGA6:ITGB1 and induces fibroblast chemotaxis through ITGAV:ITGB5.  Seems to enhance bFGF-induced DNA synthesis in fibroblasts (By similarity).  Involved in bone regeneration as a negative regulator (PubMed:23653360).  Enhances the articular chondrocytic phenotype, whereas it repressed the one representing endochondral ossification (By similarity).  Impairs pancreatic beta-cell function, inhibits beta-cell proliferation and insulin secretion (PubMed:23705021).  Plays a role as negative regulator of endothelial pro-inflammatory activation reducing monocyte adhesion, its anti-inflammatory effects occur secondary to the inhibition of NF-kappaB signaling pathway (By similarity).  Contributes to the control and coordination of inflammatory processes in atherosclerosis (PubMed:24722330).  Attenuates inflammatory pain through regulation of IL1B- and TNF-induced MMP9, MMP2 and CCL2 expression.  Inhibits MMP9 expression through ITGB1 engagement (By similarity).
What are the official names of this protein?
CCN family member 3, Cellular communication network factor 3, Nephroblastoma-overexpressed gene protein homolog, Protein NOV homolog, NovH.
What is the protein family that this protein belongs to?
Belongs to the CCN family.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Cell junction, gap junction. Note=Localizes at the gap junction in presence of GJA1.
Protein: RS27A_DAUCA
Sequence: MQIFVKTLTGKTITLEVESSDTIDNVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLADYNIQKESTLHLVLRLRGGGKKRKKKTYTKPKKTKHKHRKVKLAVLQFYKVDESGKVQRLRKECPNGECGAGTFMANHFDRHYCGK
What is the function of this protein?
Ribosomal protein S27a is a component of the 40S subunit of the ribosome.
What are the official names of this protein?
Ubiquitin-40S ribosomal protein S27a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus.
Protein: LIPB_BURM7
Sequence: MPSAPDAPAAPDAAASVAPNPPAALPVTVRWLGETPYDACFDAMRAFTDARTPDTDDEIWVVEHPPVYTLGQAGNPAHLLVADSGVPLVKVDRGGQITYHGPGQIVAYLLVDLRRRKLMVRTLVTRIEEAVIETLAAYNLASARKAGAPGIYVESGPHRGAKIAALGLKIRNGCSYHGLSVNVKMDLRPFLAINPCGYAGLETIDMASLGATADWHEVAQTLVRRLIAHLDGATAAAALPQQALEQSND
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes.  Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
What are the official names of this protein?
Octanoyltransferase, Lipoate-protein ligase B, Lipoyl/octanoyl transferase, Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the LipB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_LEGPA
Sequence: MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPMRGEIIAVGAGKVLENGDVRALAVKVGDVVLFGKYSGTEVKVDGKELVVMREDDIMGVIEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TEANC_HUMAN
Sequence: MSDKNQIAARASLIEQLMSKRNFEDLGNHLTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLSKWKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNETLGICSSNSLSSQDVAKLSEMIVPENRAIQLKPKEEHFGDGDPESTGKRSSELLDPTTPMRTKCIELLYAALTSSSTDQPKADLWQNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMANKELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDEQMMTYVICNECGEQWYHSKWVCW
What are the official names of this protein?
Transcription elongation factor A N-terminal and central domain-containing protein, TFIIS central domain-containing protein 1.
Protein: H13A7_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEKALSEGFTELIHEKEAASETEARECRYFWGECHDHMPCCDWLVCRYKWPITYNICVWNRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1a 7, U7-TRTX-Hhn1a, Hainantoxin-XIII.7, HNTX-XIII.7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CLC1B_MOUSE
Sequence: MQDEDGYITLNIKPRKQALSSAEPASSWWRVMALVLLISSMGLVVGLVALGIMSVTQQKYLLAEKENLSATLQQLAKKFCQELIRQSEIKTKSTFEHKCSPCATKWRYHGDSCYGFFRRNLTWEESKQYCTEQNATLVKTASQSTLDYIAERITSVRWIGLSRQNSKKDWMWEDSSVLRKNGINLSGNTEENMNCAYLHNGKIHPASCKERHYLICERNAGMTRVDQLL
What is the function of this protein?
C-type lectin-like receptor that functions as a platelet receptor for the lymphatic endothelial marker, PDPN.  After ligand activation, signals via sequential activation of SRC and SYK tyrosine kinases leading to activation of PLCG2.
What are the official names of this protein?
C-type lectin domain family 1 member B, C-type lectin-like receptor 2, CLEC-2.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: TCRB_BACSU
Sequence: MNTSYSQSTLRHNQVLIWLCVLSFFSVLNEMVLNVSLPDIANEFNKLPASANWVNTAFMLTFSIGTALYGKLSDQLGIKNLLLFGIMVNGLGSIIGFVGHSFFPILILARFIQGIGAAAFPALVMVVVARYIPKENRGKAFGLIGSLVAMGEGVGPAIGGMVAHYIHWSYLLLIPTATIITVPFLIKLLKKEERIRGHIDMAGIILMSAGIVFFMLFTTSYRFSFLIISILAFFIFVQHIRKAQDPFVDPELGKNVFFVIGTLCGGLIFGTVAGFVSMVPYMMKDVHHLSTAAIGSGIIFPGTMSVIIFGYIGGLLVDRKGSLYVLTIGSALLSSGFLIAAFFIDAAPWIMTIIVIFVFGGLSFTKTVISTVVSSSLKEKEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIGFLDHRLLPIDVDHSTYLYSNMLILFAGIIVICWLVILNVYKRSRRHG
What is the function of this protein?
Resistance to tetracycline by an active tetracycline efflux.  This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells.  This protein functions as a metal-tetracycline/H(+) antiporter.
What are the official names of this protein?
Tetracycline resistance protein.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: U88F3_PYRCO
Sequence: MGDVIVLYAAPGMGHIVSMVELGKLIVHRYGPHKFSITILYTCGSVVDTTSIPAYIRRISHSHPSISFCQFPRVTNKITPNISGAAIMFDFIRQNDPHVRRALQEISKSAAVRAFVIDLFCTSALPIGKEFNIPTYYFHTSGAAVLAAFLYFPKIDEQTTDSFKDLRDTVFEFPGWKSPLKAIHMVEPVLDRNDPAYSDMIYFCSHLPKSNGIVVNTFEELEPPTILQAIAGGLCVPDGPTPPVYYVGPLIDEEKELSNDAAAAEEEDCLSWLDKQPRRSVLFLCFGSRGSFPAVQLKEIANGLEASGQRFLWVVKKPPVEEKTKQVHGVDDFDLEAVLPEGFLERTADRGMVVKSWAPQVVVLKKESVGGFVTHCGWNSVLEAVVAGVPMIAWPLYAEQQMNRNVLVTDMEMAIGVEQRDEEDGFVNAEEVERRVRELMESEGGRLLRERCKKMGEMALAALGETGSSTRNLVNFVSSIT
What is the function of this protein?
Glycosyltransferase that may possess chalcone and dihydrochalcone 2'-O-glucosyltransferase activity.
What are the official names of this protein?
UDP-glycosyltransferase 88F3, UDP-glucose:chalcone 2'-O-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: AZR1_SCHPO
Sequence: MNVTRLYFRVAGTKQFARYVHKYAAYSSTSFQKKKSHFPSPATLDHPDAGEDAFINLRNENYILNAVFDGVGGWANVGIDPSIFSWGLVREIKKVFNNSDEFQPSPLTLLSKAYAALKKSNTVEAGSSTACLTLFNCGNGKLHSLNLGDSGFLILRNGAIHYASPAQVLQFNMPYQLAIYPRNYRSAENIGPKMGQATVHDLKDNDLVILATDGIFDNIEEKSILDIAGVVDFSSLSNVQKCLDDLAMRICRQAVLNSLDTKWESPFAKTAKSFGFKFQGGKVDDTTITCLLIKSKNYE
What is the function of this protein?
Confers azacytidine resistance in high copy.
What are the official names of this protein?
5-azacytidine resistance protein azr1.
Protein: METXA_HALPT
Sequence: MSRTRTTPGRRVESDVVDIGEHEFESGEILPDLKVAYEAYGEFDGQNAVLVCHGLTGSQHVAGHGTESGVSGQARAWWGDIVGPGKALDTNDYYVICVNVPGSCYGTSGPASEGPDGEPWGTDFPPVTVHDWTRAQRRLLDHLGVGRLHAVVGGSVGGMNALDWAVQFPDDVERLAVVASAARLDSQCLGIDAVARRAITSDPNWNGGDYYGEDRATPDAGLGLARQLGHLMYLSKDSMERKFGRRSAGRGDRGDAFPSDPAAAFFPYREVESYLDYQAEKFAERFDANSYLYLTRAMDDFDLSEGYESDAAALAAFEGESLLVSFTGDWHFTTEQSESLAGAFRRVDVPVAHHVVESDHGHDAFLVEPEKVGPPLGDFVDEGVAGRAVTDTATDGGEPDEEEDFAPVHSSLFSR
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1364_CLOK5
Sequence: MGIKLINIGFGNIVSANRLIAIVSPESAPIKRIIQEARDRGMLIDATYGRRTRAVIITDSDHVILSAVQPETVAHRLSTKGEEDEISEVEAQ
What are the official names of this protein?
Putative regulatory protein CKL_1364.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: HXK4_ARATH
Sequence: MGKVLVMLTAAAAVVACSVATVMVRRRMKGRRKWRRVVGLLKDLEEACETPLGRLRQMVDAIAVEMQAGLVSEGGSKLKMLLTFVDDLPNGSETGTYYALHLGGSYFRIIKVHLGGQRSSLEVQDVERHSIPTSLMNSTSEVLFDFLASSLQRFIEKEGNDFSLSQPLKRELAFTFSFPVKQTSISSGVLIKWTKGFAISEMAGEDIAECLQGALNKRGLDIRVAALVNDTVGALSFGHFHDPDTIAAVVFGTGSNACYLERTDAIIKCQNPRTTSGSMVVNMEWGNFWSSRLPRTSYDLELDAESMNSNDMGFEKMIGGMYLGDIVRRVILRMSQESDIFGPISSILSTPFVLRTNSVSAMHEDDTSELQEVARILKDLGVSEVPMKVRKLVVKICDVVTRRAARLAAAGIAGILKKVGRDGSGGGRRSDKQIMRRTVVAVEGGLYLNYRMFREYMDEALRDILGEDVAQHVVVKAMEDGSSIGSALLLASSQSVQTIPSV
What is the function of this protein?
Fructose and glucose phosphorylating enzyme (By similarity).  May be involved in the phosphorylation of glucose during the export from mitochondrion to cytosol (By similarity).
What are the official names of this protein?
Hexokinase-4.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: RSBV_LISIN
Sequence: MNISIEIKERDTDHIDIFVAGEIDAYTAPKVKEALEVYQVKEGIVLRIDLTEVSYMDSTGLGVFVGAFKSLRQRQSELVLFGLSDRLFRLFEITGLSDIIEIKNVEGEMNGNNA
What is the function of this protein?
Positive regulator of sigma-B activity.  Non-phosphorylated RsbV binds to RsbW, preventing its association with sigma-B.  When phosphorylated, releases RsbW, which is then free to complex with and inactivate sigma-B (By similarity).
What are the official names of this protein?
Anti-sigma-B factor antagonist, Anti-anti-sigma-B factor.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor antagonist family.
Protein: PURA_EHRCJ
Sequence: MVNIIVVGLQWGDEGKGKVVDWLSTNADAVVRFQGGNNAGHTIVVNDNVYKLNLLPSSVLQNGKLSIIGNGVVLDPYALISEIENLKSNGINITSQNFAISESCPLVLSVHKQADMLFEQLRQDTIGTTNKGIGPCYADKISRRAIRVCDLFDPKDLLHNKVNHLLSYHNLLRKNINNPSIETENIVNELLSIAPKILPFVQPVWKTIHNLIEQNKTIIFEGAQGTFLDIDHGTYPFVTSSNTIAQQAFIGCGINPSNKTHILGLVKAYTTRVGNGPFFTEQNNNIGKTMFESGKELGTVSNRQRRCGWFDAVLARQAVILSGVSGLVMTKLDVLDQFSEIKICVKYKYENKIYDYLPASPYIQSKLEPVYETLPGWQTSTFGSVSYKDLPQNAISYIKKIEEILKVPIYLISTGPERNSMIIINNDFLYK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDD11_ARATH
Sequence: MMNKDMLLHQHQQPQQDENMSNLTSASGDQASVSSGNITEASGSNYFPHHQQQQEQQQQQLVVPDSQTQKKRRNQPGNPDPESEVIALSPKTLMATNRFVCEICNKGFQRDQNLQLHRRGHNLPWKLKQRSNKEVIRKKVYVCPEASCVHHDPSRALGDLTGIKKHFCRKHGEKKWKCDKCSKKYAVQSDCKAHSKTCGTKEYRCDCGTLFSRRDSFITHRAFCEALAEETAREVVIPQNQNNNQPNPLLIHQSASHPHHHHQTQPTINVSSSSSSSHNHNIINSLHFDTNNGNTNNSNNSNNHLHTFPMKKEQQSNDHIMNYHHSIIPPWLAPQPHALTSSNPNPSNGGGGGGSLFSLASPAMSATALLQKAAQMGSTKTPPLPPTTAYERSTHNNNLTTTMAAMMTSPSGFISSNNNNHVLFQDYNASGFDNHGREEAFDDTFGGFLRTNEVTAAAGSEKSTKSGGGEGLTRDFLGLRPLMSHNEILSFAGLGSCINSSASDQLHPKPWQG
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Protein indeterminate-domain 11.
What are the subcellular locations of this protein?
Nucleus.