PharMolix/UniProtQA huggingface dataset:
Protein: PURT_YERPA
Sequence: MLTIGTALRPGATRVMLLGAGELGKEVAIECQRLGLEVIAVDRYADAPAMHVAHRSHVINMLDGAALKQLVAQEKPHYIVPEIEAIATDMLVELEKMGQHVVPCAEATRLTMNREGIRRLAAETLQLPTSSYRFADTDSAFFQAVRDIGYPCIVKPVMSSSGKGQSLIRSEEHLQAAWEYAQQGGRAGSGRVIIEGLVHFDFEITLLTIRAVDGIHFCAPIGHRQEDGDYRESWQPQAMSDIALQRAKEISAQVVTALGGFGLFGVELFVCGDDVIFSEVSPRPHDTGMVTLISQNMSEFALHVRAFLGLPIGTIRQYGAAASAVILPELTSQNITYRGLETALIGDTQIRLFGKPEIAGKRRLGVALAVADNIETAIEVAKKAAGNIEVSGE
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: PPNP_SALPB
Sequence: MLQSNEYFSGKVKSIGFTSSSTGRASVGVMAEGEYTFGTAEPEEMTVVSGALKVLLPGTVEWKVYTAGEVFNVPGHSEFHLQVAEPASYLCRYL
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: SYA_NEIMB
Sequence: MKTSELRQKFLKFFETKGHTVVRSSSLVPHDDPTLLFTNAGMNQFKDVFLGFDKRPYSRATTAQKCVRAGGKHNDLENVGYTARHHTFFEMMGNFSFGDYFKRDAIHFAWEFLTSPEWLNIPKDKLLATVYAEDDEAYNIWLNEIGMPSERIVRIGDNKGAKYASDNFWQMGDTGPCGPCSEIFYDHGEEIWGGIPGSPEEDGDRWIEIWNCVFMQFNRDEQGNMNPLPKPSVDTGMGLERIAAVMQHVHSNYEIDLFQDLLKAVARETGAPFRMEEPSLKVIADHIRSCSFLIADGVLPSNEGRGYVLRRIIRRAVRHGYKLGQSKPFFHKLVADLVKEMGGAYPELKEKQAQIEEALKNEESRFAQTLETGMALLENALVKGGKTLGGEIIFKLYDTYGFPYDLTADICRERNIEPDEAGFEREMEAQRARARAAQSFKANAQLPYDGQDTEFKGYSERQTESKVLALYKDGEQVNELNEGDSGAVVIDFTPFYAESGGQVGDVGYIFSGENRFEVRDTQKIKAAVFGQFGVQTSGRLKVGDSVTAKVDDEIRNANMRNHSATHLMHKALRDVLGRHVEQKGSLVTAESTRFDISHPQAVTAEEIAEVERRVNEAILANVAVNAAIMSMEDAQKTGAMMLFGEKYGEEVRVLQMGGFSTELCGGTHVSRTGDIGLFKIISEGGIAAGVRRIEAITGLNALKWAQEQERLVKDIIAETKAQTEKDVLAKIQAGAAHAKALEKELARAKAELAVHAGAKLLDDAKDLGAAKLVAAQIEADAAALREIVTDLTGKSDNAVILLAAVNDGKVSLCAGVSKPLTGKVKAGDLVKFAAEQVGGKGGGRPDLAQAGGTDADKLPAVLDSVKDWVGAKLV
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS_SHEWM
Sequence: MFDQTTNTETHQLTVGKIETANGTIKPQLLRDAVKRAVTNFFAQMDGQEAEEVYEMVLSEVEAPLLDIIMQHTRGNQTRAANMLGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: RS14Z_SYNFM
Sequence: MAKKSLIAKAKRTPKFGVRTYNRCPICGRPRAYLRKFGICRICFRSMALKGELPGVVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: KCND1_BOVIN
Sequence: MAAGVATWLPFARAAAVGWLPLAQQPLPPAPGVKASRGDEVLVVNVSGRRFETWKNTLDRYPDTLLGSSEKEFFYNADSGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGDGPTLPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRSPTRRPPREQPCGDRFPLAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYYIGLFMPKNEDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYKQNGSLEDSGGGEEQALCVRNRSAFEQQHHHLLHCLEKTTCHEFTDELTFSEALGAVSLGSRTSRSTSVSSQPVGAGSLLSSCCPRRAKRRAIRLANSTASVSRGSMQELDTLAGLRRSPAPQSRSSLNAKPHDSLDLTCDSRDFVAAIISIPTPPANTPDESQPSSPGGGGGGASSTLRNSSLGTPCLLPETVKISSL
What is the function of this protein?
Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels.  May contribute to I(To) current in heart and I(Sa) current in neurons.  Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits (By similarity).
What are the official names of this protein?
Potassium voltage-gated channel subfamily D member 1, Voltage-gated potassium channel subunit Kv4.1.
What is the protein family that this protein belongs to?
Belongs to the potassium channel family. D (Shal) (TC 1.A.1.2) subfamily. Kv4.1/KCND1 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Cell projection, dendrite.
Protein: EFG_BURM9
Sequence: MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGNNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLKLRLKANPVPVVVPIGAEENFKGVVDLLKMKAIIWDEASQGTKFDYVDIPAELADTCQEWREKMVEAAAEASEDLMNKYLEEGDLPEADIVKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELESGEAAERQASDEEKFSSLAFKIMTDPFVGQLIFFRVYSGVVNSGDTLLNSTKGKKERLGRILQMHANQREEIKEVRAGDIAAAVGLKEATTGDTLCDPAHPIVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEATVGKPQVAYRETIRSTAKDVDGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRRANPVVLEPMMAVEVETPEDYMGNVMGDLSGRRGIVQGMEDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPKNVADAIISAKSK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAA_ECO81
Sequence: MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: GREA_MESH2
Sequence: MKNTVNDKILLTQQKLEEIEKELEHLINVERVNVIQEIKDARSQGDLSENAEYDVAREKQGIIESRIRELETIISKAKIIKADLGSSRVSIGSKVSLENVESGEIQTFQIVSSIDADPFKSKISNFSPIAQALLGQHQGDEVEVDVNEKYSVRILEVINE
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MIAB_SHEB8
Sequence: MSKKLHIKTWGCQMNEYDSSKMADLLGEYQGYTLTEEASEADILLLNTCSIREKAQEKVFHQLGRWKTLKDKNPNLIIGVGGCVASQEGKAIKDRAQCVDIIFGPQTLHRLPEMIEQVRRGDKAVIDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCSKYCSFCVVPYTRGEEVSRPSDDIILEIAQLAEQGVREVNLLGQNVNAYRGATHDGAICTFAELLRFVAAIDGIDRIRFTTSHPIEFTQDIIDVYEDTPELVSFLHLPVQSGSDRILTAMKRGHMAIEYKSIIRRLRKAREGIQISSDFIIGFPGETKEDFADTMKLIEDIGFDHSFSFIYSARPGTPAADLPDNVDMEEKKQRLAILQDRITQQAMRYSRHMMGTVQRILVEGPSVKNPMELRGRTENNRVVNFEGQPKHIGTFVDVEIVDVYTNSLRGVFIRGEDEMDLRRSLRPAEILAKRKQDDELGVTQFKP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXD_CHLFF
Sequence: MPQELVYTLQQLADLLKVEVQGNTETPISGVEEISEAQSHHVTFLDNEKYSRFIKNTEAGAIILSKAQAQKYGHLNKNFLIVSEFPSIAFQKCIELFIPPIDSGFPGIHPTAVIHPTAHIGKDVFLEPYAVICQHAQIGDSSHIGAGSVIGAFSTLGEHCYVHPKVVIRERVVIGKRVIVQPGAIIGACGFGYITNAFGRHKHLKHLGQVIIEDDVEIGANTTIDRGRFKNSVIREGTKIDNQVQIAHHVEVGKHSMIVAQAGIAGSTKIGNHVIIGGQTGITGHISITDHVIMMAQTGVTKSISSPGIYGGAPARPYQEIHRQVAKIRGLPKLEERLGMLEEKVKGLSAQSEEAQITP
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: Y843_ARCFU
Sequence: MIFKFFCLDLQSCKHHLKPYIVQKGFKGVKVKDAPKTATSIIVRSASNARISQSKMPMLELMRRIFRKEEVALKAVKFLTLVEERQKSGKPLRVEEWEQIMEELGMVRSSFYSMRNKLLGAGMITIRNGEYHLSGAFSKDLVDMARWWWVVVLGYDPESL
What are the official names of this protein?
Uncharacterized protein AF_0843.
Protein: TARI1_STAAM
Sequence: MKYAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILINDFEKIIIATPQQWMTHTKDTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGINDDDVIVTHDAVRPFLTHRIIKENIQAALEYGAVDTVIDAIDTIVTSKDNQTIDAIPVRNEMYQGQTPQSFNINLLKESYAQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKVTTPYDLKVANAIIRGGIADD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: SECA_TRICV
Sequence: MLKNPFKKKSIADKYQTLIREINALESTVKTLTDGELRNKTNQLKQRYQDEQNLNNLIVESFALTREASYRTLGLRHFDVQLIGGLVLNGGKIAEMRTGEGKTLVATLPAYLNALTKKGVHIVTVNEYLASRDQTSMGQIYRFLGLETGLIQEKMTTPERQRNYKADITYVTNNELGFDYLRDNLALNIRDVFLRPFNYCIVDEVDSVLIDEALTPLIIANSVKTCVDKYIIASEITDYLELNVHFEIDEKNKSVLLTNQGTIQIEKILGVQDLYNPRDPWIPYVINAIRASSLFFRDVHYIVQNNRIVIVDEFTGRIMPDRRWRHGLHQAVEAKENVAIRQTTEITASITYQNFFLVYPKLSGMTGTAKTAEVEFDKIYSLPVEEIPTARPNLRQDLPDLIYKDEFSKWNAIAKECQNISLVKQPILIGTTTVEKSEMLAQLLQEYRLSHQILNAKPENVRRESEIVAQAGKKGSITIATNMAGRGTDIILGGNIQFKVRKDLYNILVTYKYQTKENKKDSLSRSLQIFPLLKKLQRTSQKFLTVLNCLINNKQFLNLSDVEVLKILNESELIRVPKISYQCSMKFLINELVNFEKKTQKLDNVIVKNLGGLYIIGTERNDSQRIDNQLRGRCGRQGDPGKSRFFLSVEDKLIRLFGDARLENVLKSQLLDDLPLESELVTKILDSAQKRVEERNYELRKNLFDYDDILNKQRNVVYYERRKVLESESARIKILAYGEQVISEITSKLRRKKVFGSQLISRIRNLLGTKFLLNFPSSDLNNLESIDFQTYLLQEFWLSYESKILELEVEYPGIIQEFERTLILIYMDREWKEHLQKMSLLRDAVGWRKYGQRNPLSEYKEDAYKLFKYRGIVTRHLVIYELLRSSIL
What is the function of this protein?
Has a central role in coupling the hydrolysis of ATP to the transfer of proteins across the thylakoid membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein. Note=A minor fraction is associated with the chloroplast thylakoid membrane.
Protein: COBQ_METMP
Sequence: MAKFIMVVGTSSNSGKTVLVSGICRMLSNKGYKVAPFKSQNMSLNSRVSVEDGEIAVAQYTQAMAARAEPSVHFNPILLKPKGNFVSQVIVHGNPYEDKDYNEYRSKKDDFLVKIKESIDYLDKNYDYVVIEGAGSCCEINLLNDDIANLKVAEIAGADAILVSDIDRGGVFASIYGTVQLLPENWKKLLKGFVINKFRGNIDVLKDGFEKIEELTNIPVIGTIPYDETLVLPEEDSQALDGKRVFGNLKSPIEVNVVKFSKIANFTDVDPFSSDCLMKYIDFNENITGDILILPGTRCSTVEMDLMKKYGMDKKILEFVENGGIVLGICGGYQALGKMLFDEDFSEGDVGTISGLGLFDMETTFGNKKAIKNSTGKISIFNQNFDVSGYELHEGYSVSNETPLISLSKGFGNCGDSYDGSFKMIGDSYIFGTYFHGILENFEFRNYLVNLARSKKNLSKIEDDTYAELFNENMDKLSKIIEENLDFSKIIG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Probable cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: DRS4_AGACL
Sequence: MAFLNKSLLLVLFLGLVSLSICEEERRENEDEEEQEDDEQSEMRRSLLSTLGNMAKAAGRAALNAITGLVNQGEQ
What is the function of this protein?
Has antibacterial activity against Gram-positive bacterium M. luteus NCT C2665 but not against Gram-negative bacterium E. coli K12D31.
What are the official names of this protein?
Dermaseptin-related peptide, DRP-AC4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NFH_PIG
Sequence: MRGAVLRLGAARGQLRLEQEHLLEDIAHVRQRLDDEARQRQEAEAAARALARFAQEAEAARVELQKKAQALQEECGYLRRHHQEEAQAEARDALKCDVTSALREIRAQLEGHAVQSTLQQEEWFRVRLDRLSEAAKVNTDAM
What is the function of this protein?
Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber.  NEFH has an important function in mature axons that is not subserved by the two smaller NF proteins.  May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
What are the official names of this protein?
Neurofilament heavy polypeptide, NF-H, 200 kDa neurofilament protein, Neurofilament triplet H protein.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, axon.
Protein: CED6_DROME
Sequence: MPYQPANSGGTSGGSKAAAKMAQLKFWNKQNSSKQQQQDKDKDAADGGNNTSGGGTGSNSNGDAKSEAKNGKRNWLHTPEQLISGHAVYLVKFFGNLSVDQPKGIEVVKEAIRKLQFAQQMKKAETGTQEKFKKLEITISIKGVAIQEPRTHKILHQFPLYNISYCADEKGVKKFFSFIAKTVKTQDGSDPTSNGHANGNGDGSAKVEESHECFVFISNKLASDITLTIGQAFDLAYRKYMDSTEKTNLSKAQQQINHLQQTVNVYKERLREVSAKLPKAELDALLFNLGIKDILEAPTTEPQNGIEVASEALSNGKLDDDKLLIDTNSTTASTHSASPSSFLPIVPPRNNLSSQISIGGKSNSQKMDELLLNSDSDSDFDPRADETQEIGGTGRSAISNMFGFEPANSFGQHLFSNNNDHKLQNNNSSLLITSNNNSINSSGFSSELNITPPLLAPPPKIAAPRRLNSVTTGNGLNGNTDLFGSDPFELNNGPNIFKQNQLNLDDFSLESLDPLRK
What is the function of this protein?
Plays a role in axon pruning in larval mushroom body neurons during metamorphosis (PubMed:16772168).  Plays a role in the infiltration of glial cell processes into mushroom body lobes and the subsequent engulfment of degenerating axon branches (PubMed:16772168).  Involved in Drpr-mediated phagocytosis of apoptotic cells (PubMed:19927123).  Required for bacterial phagocytosis (PubMed:19890048).  During neuromuscular junction development, required for the clearance of pruned ghost boutons and presynaptic debris and for normal synaptic growth (PubMed:19707574).
What are the official names of this protein?
PTB domain-containing adapter protein ced-6, Cell death protein 6 homolog.
What is the protein family that this protein belongs to?
Belongs to the ced-6 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPF_CRUWA
Sequence: MKNLTDSFVYLGHWPSAGSFGFNTDILATNPINLSVVFGVLIFFGKGVLNDLLDNRKQRILNTIRNSEELREAAIQQLENARARLRKVETEADQFRVNGYSEIEREKLNLINSTYKTLKQLENYKNETILFEQQRTINQVRERVFQQALQGAIGTLNSCLSNELHLRTINANIGMFGTMKEITD
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, chloroplastic, ATP synthase F(0) sector subunit b, ATPase subunit I.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CHEB2_ALBFT
Sequence: MVVDDSAVVRQVVAGLLADDPAIEVIAAVADPILAIARMKVQWPDVFVLDIEMPRMDGITFLKKIMAERPTPVVICSTLTEKGAQTSMAALSAGAVAIITKPKLGLKQFLVDASDDLISAVKAAARANVKRLQVVEKLTADAILPASDRHDAMLQTTERVVALGTSTGGTQALEVVLTALPRVTPGIVIVQHMPEKFTAEFANRLNGLCQITVREAKNNDRVVPGRALIAPGGKHMLLRRNGAQYSVEVLDGPLVNRHRPSVDVLFRSVARCAGANALGVIMTGMGDDGAAGLAEMRKAGARTLAQDEESCVVYGMPKEAVKRGGVERSVPLGAIAREIMAQMAG
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_LACP3
Sequence: MQYSEIMVRYGELSTKGKNRQAFIGRLNGNVTRALHEFPNLTIRPKRDRMHIELNGEPSDQVMARLSQVFGIQNFSPSIAVEKDMDKVHAVALQLMNETAPKGISYKVNTRRSDHDFALDTNAMNLDLGDYLTDKRPDLVVKMHQPDMILRVEVRREAIYLSTKTIQGAGGLPVGTAGKAALMLSGGIDSPVAGYYALKRGVDIEMVHFFSPPYTSQQALNKAKQLTAKLTPYVGRIYFIEVPFTEIQEEIKAKVPEGYLMTVQRRLMLRLTEAIAQQRGDLAIFNGESVGQVASQTLESMAAINDVTTMPIIRPVATMDKNEIIAEAEKIDTYDLSIMPFEDCCTIFAPPSPKTKPKTDRARYYESKIDVAGLMDRALAGVKIQEIKSSDQFMNQDQDVIAELL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_PARMW
Sequence: MGSFRCMSPASPSWSGLLELLLCGESLSAAQATDLMQAWLSESLTPVQTGAFLAGLRAKGMEAEELAAMAAVLREACPLPCARPDRFLVDTCGTGGDGADTFNISTAVAFTAAACGVEVAKHGNRSASGKVGSADVLEGLGLNLKAPLQLVVDAIPAAGVTFLFAPAWHPALVNLAPLRRSLGVRTVFNLLGPLVNPLKPQAQVLGVAKKDLLDPMAGALQRLGLERAVVVHGAGGLDEASLAGPNDLRFIEAGAIRSLQLSPDELGLATADLETLKGGDLDCNQTILQQVLQGRGEPAQRDVVALNTALVLWAAGIDTDLSSAAARAAEALDQGLPWTRLETLRQHLAS
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: ENO_GEOKA
Sequence: MSAIIDVYAREVLDSRGNPTVEVEVYTEDGGFGRALVPSGASTGEYEAVELRDGDKNRYLGKGVLKAVENVNEIIAPEIIGLEVADQVAIDRKLIELDGTENKSKLGANAILGVSLAVARAAADELGLPLYQYLGGFNAKTLPVPMMNILNGGAHADNNVDIQEFMIMPVGAESFREALRMGAEIFHSLKAVLKAKGYNTAVGDEGGFAPNLKSNEEALQTIIEAIEKAGYKPGEQVMLAMDVASSELYNKEDGKYHLEGEGVVKTSEEMVAWYEELVSKYPIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLAEGIEKGVGNSILIKVNQIGTLTETFDAIEMAKRAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGAPSRTDRVAKYNQLLRIEDELGHTAIYQGIRSFYNLKK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MEII1_MOUSE
Sequence: MTAADHPAFGRDEEAALLLERTHHRHDPRWLLPVSPHVCMACALELLPEPGVSLVRKKHVVFCFQDALVRHTSLVAQLVAQDQRVCIHFVRVLFGLLNSVEDGSMADLCIEVLVQLTTQPNMEQTIRCLMNECHRELCNLRSMGGSLATTTLLGKLVDTIPGLADELVMEHGNLMEHLLRGLVYPNEGVQASICYLYGKLYSSPTAAEMLSGHFREKLCALFLSTLDSAQTKDLQINCLGLLRQLLKYDLFVSLIMNKSVPVEGAESVERPSRETSLPLVLKKFLLSRDEILQVASSHCITAVLVHSPAKHAVAFIHADIPEFLFEHLSSSSEILVWSSYNCLILLAEEPLFFSKCHTVYGIEAVVRSLQGSQQMTNTELHTQGLLLFKEILTRQPEEIRLFTSSALCRDASRALQEAVSSPVLAVAAEALRAISAFLRKDHQSSLPVQYRALRALLEAMLSRCMEFSQTPLNRRSLGHACSRNSEKATLRKGSFLLSTLEGFRNACRLAVEFQGEPSAQENPFTAPSAEKEDTLEAFSEYLLSACDSQCIPMVMRYSEEATHPKLMEVFLSILHSLFVIIPHMKVKFSRKLADSSFIRLTLELKARFCSGQSHSSLNQVCSSFLYYMCLNLLSAPEKTEPLSQEELSAVSEFLQHGLPHISSRTPESLAFLSDRQYVEAATRQRQYCILLLFYLAHIHDDRFVPEAELFVAVQSFLLSLQDQGECPPPVVCKASMYLLAVCGDKDSALAEAVISAIRKFLEGIPDLRGVYTHHPLLLRFFLAYPGLMSRFGHRVLELWFSWEESGYENLDDDSSPGRTVFPANLAALFRVLQSTPSILLILLDLVYSSPVDTARKVLIVLRVFLWENEDVKVGGLIRGHFLLILQRLLVEYGASTSGGNLPLLLNLLSLVQMRNESEQELDSMAMKLLHQVSMLCGKCSPAHVDILQPSFNFLYWSLHQTTPSSQKRAAAVLLSSTALLELLEKMLALTWTETGSSPRTPLLSSAWLLTASFSAQQHNGNLQVHRTLSVELNQVLKALSFPKKMSALLSAAILRFLRTALQQSFSSALVVLVPSGDQPLSTPEDAVLAPLGKSQVLALLIGLQNLLVQKDPLLSQACIGCLEALLDYLHARSPDIALHVASQPWNRFLLFTLLDAGENSFLRPEILRLMTLFVQYRSSCVLSREEVGLILQGAALVDLSALSNDTLQALHGFLLQVQSMGLLNDQHMTQTLQSSLEGLCSRTFPAQPLFQDMLCLGGVSVSQAHIRG
What is the function of this protein?
Required for normal meiotic chromosome synapsis.  May be involved in the formation of meiotic double-strand breaks (DSBs) in spermatocytes.
What are the official names of this protein?
Meiosis inhibitor protein 1, Meiosis defective protein 1.