PharMolix/UniProtQA huggingface dataset:
Protein: ACEK_SERP5
Sequence: MAAKLELLIAQTILQGFDAQYGRFLEVTAGAQQRFERADWPAVQQAMKKRIHLYDHHVGLVVEQLKCITGQQYFDADFPSRVKAVYTDLLPEYPRFEIAESFFNSVYCRLFRHRDLTPEKLFVFSSQPEGRFRDIPRPLSRDFTANGDVSAMLYNLLTDLPLRLPWENLSRDIDYITLALQQSFSAQQLAGATFQIANELFYRNKAAWLVGKLRVADRVYPFLLPIHHSDSGALFIDTCLTSKAEASIVFGFARSYFMVYAPLPAAMVEWLREILPGKTTAELYMAIGCQKHGKTECYREYLTFMSGSQEQFIIAPGVKGMVMLVFTLPSFDRVFKVIKDEFAPQKEVTQAQVMACYQLVKEHDRVGRMADTQEYENFVVDKARLSPELLAELQREVPDKLEDLGDRIAIRHLYMERRMTPLNLYLEQADEQQMRDAIEEYGNAIKQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPNDVFPEEFRHFLCGDRRIRQVFEEMHRDLFEADYWRGLQQRIRDGHVEDVFAYRKKRRFSQRSGAALPATSATA
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_BORPA
Sequence: MSLLHRASFYISAARLDQLPPAGAPEVCFVGRSNAGKSSAINVLCNQRRLAFSSKTPGRTRLINMFGLPDPLAPGEQLGFLVDLPGYGYASVAHREKEKWADILGGYLRDRASLAGIVLLIDIRRGVTDLDRRLTNFIAPTGRPVLALLTKADKLPYGQRMRTVFAVRKDLADIGALHMVPFSSTERIGLEEAGAHIENWISPKVVP
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: PUMA_PARUN
Sequence: MEGTCSEEENLAKRVTPTAVTSGTYGTHVVDTTDLALSDVVIGCGSTIYETSDSIGSDVMLGLSSHGVSSVSGLDRDLNSFKKRIDANTEEQREHADMMVGLQRKIEEYRRRIVDAEKQVSIQKANDDVSFSIKETADTWLPDMKSDAADYEWASRLDEERRRNDELHMQITQQQVDLQRLQKYFEANMQEKEKIYQTREKNLAYYLNAEQRKMLDLWEELQRVRRQFADYKEQTERDLENQKNEVAKVTQSVGGMAGRLNTSSHGDSGLVQDVVLLEAMRRFRELQAVPVGASADDYNALMKKYEETVERVIELESHGDGSTAKMLSLEAELRRTKDKFIECSEFLRKLGDLAAGSYRGDERTSKIVSLSPGGMSLPSEIYRSVRNILRNHDSEMQHIQRKLKNSDTQVCELTTRLEGTEEARRRSDKQLVDAKREINIQQRAVDDANRELRRVEDRLHIMESEKIVAENARQQLEEEVRRLTLQVDQSKADGERRVVEEGEIQKRIVEDEYRSMISELTRRMNAFQDENKRLKNDLGCTKERLKNVEFEYNSTVRKLEDKDIALKHLEDTKLDLLKDLENQRTRYDAVTNELDTLQTTFETSTKNIAQLEANIKEINLMRDEISKEKDSLAQKLADVTHKLEIETVRREDIQRSCVGHSEDVEKQRLQIIEYEREVMALRRLNDELDTNVKTGQAKVTSLENSIISVQTEVTKLTTLNDKLQKEKQSIMSSKQKADTDVDLLKEKLRKLEQECDKLKEENKALHEDEQIARQMCKEEASRIHLLERDLKDAMTEVEELKKQLQKMDEENSERLESVLRTKISSDTVDTSEIAEYTEVKVKELREKYKADLERLQSNKDDLERRVQILEDELAERQRIVERQRTEMNDLKLEYQLESDRLRAEMATVELKYQSEVEDERDQRSRDADSWKVTSEELRSKISFMEKMLEEAKHRETVLREEATEWEEKHDIISNESLKLRNEIERIRSDAEEDIQKWKKDVHMAQNELKNLERVCETLRSQLTAANDRVASLNTTINEQTSKIRELNSHEHRLEEDLADSRATSSAIENDLGNATGRLRSSEEHNAILQSENRKSKTEIEALKHQIDTIMNTKESCESEVERLKKKIVQTTTITKEQNEKIEKLRIEHDHLERDYREKTKEVDRLKEVEKTFELKVNRARQELDEFSKKLIVTETERNAISGEAQKLDKEVQLVKEQLQYKSDEFHKALDELANAHRISEEGRVNAIHQLEARRFEIDDLKSRLENSEQRLATLQQEYVNADKERGALNDAMRRFQATISRSVVAEEHVDVSTIETQMQKLMSRIEAIERERNEYRDSLNRLKNRCSTSYSSVDRQETVYRTFEERVISAEDERRKVELKLSSMKEMLKSQEEKLKQRDEERRNLKSNIVTFELEARAKDAQIRHLNDLLKRVQAELENSQNDNRALRERQEQYETNRIHLEQRLPTDEGEPRVKALMAAFATERQSLSDSLKKLASQLQISETKNADLRDDAERLKRDLLKAERVEEDLRRNLVEQTEIMRENQQLRSQLGVAQSDLANASGRKQQLEGELAAVRAELRDHKQHLHDAISRIAELQRQLQDANAEKSRLTDRIIGLEKTIGTLRNTETELRAQLSTAADERKALNSELEEMRRRIVQMESEKKDVDNQLEEVNKARIIMTKKIEILETEKHSAELVISETASQREAIERSLNALERENKELYKNCAQLQQQIAQLEMDNGERLIALTTKQKEDHEKFVAAVKAEKVQVERIVENRDRAQKSRIRQLENQLSMMREQLDNERARSHQMSERFIVNETNRRVSSSSFRLSGDAAGVAAATILHPQTDRLDYVFANRSALSSYYTVPTEQHASRGKEAYRTSSTIKSSEGTTRESYTYQSRTVSSNIIEQANGMTSSASGEGMSRAYPPTEVNQGDVTGRKSRPATRKQQMKSTFSE
What is the function of this protein?
May play a role in the organization of the spindle apparatus and its interaction with the centromeres.
What are the official names of this protein?
227 kDa spindle- and centromere-associated protein, PUMA1.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Chromosome, centromere. Note=Centrosomes and kinetochore microtubules of mitotic cells. Also localizes to the spindle mid- zone region during anaphase and to the midbody during telophase. During meiosis, associates with centrosomes and discrete centromeric regions lacking kinetochore structures.
Protein: RASF3_MOUSE
Sequence: MSSGYSSLEEDEDFFFTARTSFFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNSAVTDKLKMTLNSNGIYTGFIKVQMELCKPAQPSPEPSSGGCMNTLHISSTNTVGEVIEALLRKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGEWEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKLEEALGEVWKPG
What are the official names of this protein?
Ras association domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Localized to microtubules in vascular endothelial cells.
Protein: COBS_CLOBK
Sequence: MKSILNDFLLMIQFFTRIPVNKNLQCEKENFRRGAFFLPVVAFIIGGMEFLIYLALKNFLPPNVIIVLLILFTAMITGGLHMDGLADTCDGFFSLRDKERIIEIMKDSRIGSYGTIALIIDLLLKYQLLYSLVLKGYSIAIVLAPIIGRISILFLCLSKRTAKKNGSGNIFIGNMSKPIIFFITTIVLALSTYFLGLRATIIPFIGVLLITYLLYLLCLNKINGLTGDTLGACNELGEITFLLILLMI
What is the function of this protein?
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin).  Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
What are the official names of this protein?
Adenosylcobinamide-GDP ribazoletransferase, Cobalamin synthase, Cobalamin-5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the CobS family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL9_MICLC
Sequence: MAKLILTQEVAGLGTSGDVVEVKNGYARNYLLPRGFATVWTKGGEKQVESLQKARAARAVANLEDAQAQAAQLQSAPVQLERTAGAEGRLFGAVQTADVAEAIEAAGLGSVDKRSITLPAHIKSVGNHEAQVRLHEDVIATVQLQVVAAKAKK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: 3L277_DRYCN
Sequence: MKTLLLTLVVVTIVCLDLGDSLICYMGPKTPRTCPPGENLCYTKTWCDAFCSIRGRRVDLGCAATCPTAKPGVDITCCSTDKCNPHPAHQSR
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Long neurotoxin 77, LNTX-77.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CATA_SCHPO
Sequence: MNSKDSNTVPVYTTNTGCPIFNPMAAARVGKGGPVLLQDSHLIDVFQHFDRERIPERVVHAKGSGAFGEFECTDDITKYTKHTMFSKVGKKTPMVARFSTVGGERGTPDTARDPRGFALKFYTDEGIFDMVGNNTPVFFLRDPAKFPLFIHTQKRNPQNDMKDATMFWDYLSQNAESIHQVMILFSDLGGTPYSYRFMDGFSSHTYKFVNDKGEFYYCKWHFITNQGTKGLTNEEAAALDGSNPDHARQDLFEAIERGDYPSWTLYVQVMTPQEAEKYRYNIFDLTKVWPHKDVPMQRVGRFTLNQNPTNFFADIEQAGFSPSHMVPGIEVSADPVLQVRTFSYPDTHRHRLGANFEQIPVNSPKCPVFNYSRDGPMNVNGNQGNWPNYPSSIRPLAKVQYEPDEGHEKWVGQVTYHMDEITDVDFEQPRAFWQNVLGKKPGQQDNFVKNVAGHLSGAISPVRERQYGVFTRVDSELGRRIREATEAEVKKMEEKAPKPINKGEPHMFQGSS
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
Protein: YDAT_BACSU
Sequence: MPWSMKDYPASLKNLEKPVRKKAIDIANAMIDEGYEEGRAIPIATSKAKEWAENASTDEIDDFLTHDDETERDADPSSGSGPELMNKAEHVIKHKKGWAVKAEGAKRVSEIKDTKKEAIERAKEIAAHKGTEVIVHLADGSVQRKIKTGS
What are the official names of this protein?
Uncharacterized protein YdaT.
Protein: FAL1_YEAS7
Sequence: MSFDREEDQKLKFKTSKKLKVSSTFESMNLKDDLLRGIYSYGFEAPSSIQSRAITQIISGKDVIAQAQSGTGKTATFTIGLLQAIDLRKKDLQALILSPTRELASQIGQVVKNLGDYMNVNAFAITGGKTLKDDLKKMQKHGCQAVSGTPGRVLDMIKKQMLQTRNVQMLVLDEADELLSETLGFKQQIYDIFAKLPKNCQVVVVSATMNKDILEVTRKFMNDPVKILVKRDEISLEGIKQYVVNVDKEEWKFDTLCDIYDSLTITQCVIFCNTKKKVDWLSQRLIQSNFAVVSMHGDMKQEERDKVMNDFRTGHSRVLISTDVWARGIDVQQVSLVINYDLPEIIENYIHRIGRSGRFGRKGVAINFITKADLAKLREIEKFYSIKINPMPANFAELS
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase FAL1, Translation initiation factor four A-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX48/FAL1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: LCL3_YEAS1
Sequence: MREGDSNSKKSADVAVLSIILTGSTLTLIYTYKRYLTQFKRTNDIPRRIFRKHWLYGKVTSVGDGDNFHFFHMPGGIRGGWGWLRPVPQMIKNDSTAEKLVGDSRNMRFFNFNWITHGRSTKSKIQKAKSQFLKLNVPYKNRKNLPTIPIRLCGIDAPERAHFGNPAQPFGNEALIWLQNRILGKKVWVKPLSIDQYNRCVARVSYWDWFGGWKDLSLEMLKDGLAVVYEGKVNTEFDDREDKYRYYEFLARSRKKGLWIQNKFETPGEYKKRI
What are the official names of this protein?
Probable endonuclease LCL3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: DHRS4_BOVIN
Sequence: MLKVGLPLGACARSWKSVRMASCGMARRNPLDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLTKAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVRVNCLAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSEDASYITGETVVVAGGSLSHL
What is the function of this protein?
NADPH-dependent oxidoreductase which catalyzes the reduction of a variety of compounds bearing carbonyl groups including ketosteroids, alpha-dicarbonyl compounds, aldehydes, aromatic ketones and quinones.  Reduces all-trans-retinal and 9-cis retinal.  Reduces 3-ketosteroids and benzil into 3alpha-hydroxysteroids and S-benzoin, respectively, in contrast to the stereoselectivity of primates DHRS4s which produce 3beta-hydroxysteroids and R-benzoin.  In the reverse reaction, catalyzes the NADP-dependent oxidation of 3alpha-hydroxysteroids and alcohol, but with much lower efficiency.  Involved in the metabolism of 3alpha-hydroxysteroids, retinoid, isatin and xenobiotic carbonyl compounds.
What are the official names of this protein?
Dehydrogenase/reductase SDR family member 4, NADPH-dependent carbonyl reductase, CR, NADPH-dependent retinol dehydrogenase/reductase, NDRD, Peroxisomal short-chain alcohol dehydrogenase, PSCD, Short chain dehydrogenase/reductase family 25C member 2, Protein SDR25C2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PATL2_ARATH
Sequence: MAQEEIQKPTASVPVVKEETPAPVKEVEVPVTTEKAVAAPAPEATEEKVVSEVAVPETEVTAVKEEEVATGKEILQSESFKEEGYLASELQEAEKNALAELKELVREALNKREFTAPPPPPAPVKEEKVEEKKTEETEEKKEEVKTEEKSLEAETKEEEKSAAPATVETKKEEILAAPAPIVAETKKEETPVAPAPVETKPAAPVVAETKKEEILPAAPVTTETKVEEKVVPVETTPAAPVTTETKEEEKAAPVTTETKEEEKAAPGETKKEEKATASTQVKRASKFIKDIFVSVTTSEKKKEEEKPAVVTIEKAFAADQEEETKTVEAVEESIVSITLPETAAYVEPEEVSIWGIPLLEDERSDVILLKFLRARDFKVKEAFTMLKNTVQWRKENKIDDLVSEDLEGSEFEKLVFTHGVDKQGHVVIYSSYGEFQNKEIFSDKEKLSKFLKWRIQFQEKCVRSLDFSPEAKSSFVFVSDFRNAPGLGQRALWQFIKRAVKQFEDNYPEFVAKELFINVPWWYIPYYKTFGSIITSPRTRSKMVLSGPSKSAETIFKYVAPEVVPVKYGGLSKDSPFTVEDGVTEAVVKSTSKYTIDLPATEGSTLSWELRVLGADVSYGAQFEPSNEASYTVIVSKNRKVGLTDEPVITDSFKASEAGKVVITIDNQTFKKKKVLYRSKTQA
What is the function of this protein?
Carrier protein that may be involved in membrane-trafficking events associated with cell plate formation during cytokinesis.  Binds to some hydrophobic molecules such as phosphoinositides and promotes their transfer between the different cellular sites (By similarity).
What are the official names of this protein?
Patellin-2.
What is the protein family that this protein belongs to?
Belongs to the patellin family.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cytoplasm. Note=Mainly membrane- associated. Also cytoplasmic (By similarity).
Protein: RNF38_HUMAN
Sequence: MACKISPGANSASLPGHPNKVICERVRLQSLFPLLPSDQNTTVQEDAHFKAFFQSEDSPSPKRQRLSHSVFDYTSASPAPSPPMRPWEMTSNRQPPSVRPSQHHFSGERCNTPARNRRSPPVRRQRGRRDRLSRHNSISQDENYHHLPYAQQQAIEEPRAFHPPNVSPRLLHPAAHPPQQNAVMVDIHDQLHQGTVPVSYTVTTVAPHGIPLCTGQHIPACSTQQVPGCSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLIHPPHLSPHHPPHLPPPGQFVPFQTQQSRSPLQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPPPYHPSLLPYVLSMLPVPPAVGPTFSFELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRDSE
What is the function of this protein?
Acts as an E3 ubiquitin-protein ligase able to ubiquitinate p53/TP53 which promotes its relocalization to discrete foci associated with PML nuclear bodies.  Exhibits preference for UBE2D2 as a E2 enzyme.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF38, RING finger protein 38, RING-type E3 ubiquitin transferase RNF38.
What are the subcellular locations of this protein?
Nucleus.
Protein: BIP_ASPKA
Sequence: MARISHQGAAKPFTAWTTIFYLLLVFIAPLAFFGTAHAQDETSPQESYGTVIGIDLGTTYSCVGVMQNGKVEILVNDQGNRITPSYVAFTDEERLVGDAAKNQYAANPRRTIFDIKRLIGRKFDDKDVQKDAKHFPYKVVNKDGKPHVKVDVNQTPKTLTPEEVSAMVLGKMKEIAEGYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVLRVVNEPTAAAIAYGLDKTGDERQVIVYDLGGGTFDVSLLSIDNGVFEVLATAGDTHLGGEDFDQRVMDHFVKLYNKKNNVDVTKDLKAMGKLKREVEKAKRTLSSQMSTRIEIEAFHNGEDFSETLTRAKFEELNMDLFKKTLKPVEQVLKDAKVKKSEVDDIVLVGGSTRIPKVQALLEEFFGGKKASKGINPDEAVAFGAAVQGGVLSGEEGTGDVVLMDVNPLTLGIETTGGVMTKLIPRNTVIPTRKSQIFSTAADNQPTVLIQVYEGERSLTKDNNLLGKFELTGIPPAPRGVPQIEVSFDLDANGILKVHASDKGTGKAESITITNDKGRLSQEEIDRMVAEAEEFAEEDKAIKAKIEARNTLENYAFSLKNQVNDENGLGGQIDEDDKQTILDAVKEVTEWLEDNAATATTEDFEEQKEQLSNVAYPITSKLYGSAPADEDDEPSGHDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.  Is required for secretory polypeptide translocation.  May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, Immunoglobulin heavy chain-binding protein homolog, BiP.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: LANA_ACTGA
Sequence: MSALAIEKSWKDVDLRDGATSHPAGLGFGELTFEDLREDRTIYAASSGWVCTLTIECGTVICAC
What is the function of this protein?
Has potent antibacterial activity against some Gram-positive bacteria (PubMed:19400806).  Has good antistreptococcal activity.  Inhibits cell wall biosynthesis by binding to lipid II and blocking transglycosylation (PubMed:9449277).
What are the official names of this protein?
Lantibiotic actagardine, Gardimycin.
What is the protein family that this protein belongs to?
Belongs to the type B lantibiotic family.
Protein: CH60_RICM5
Sequence: MATKLIKHGSKAREQMLEGIDILADAVKVTLGPKGRNVLIEQSFGSPKITKDGVTVAKSIALKDKIRNAGAQLLKSAATKAAEVAGDGTTTATVLARALAREGNKLVAAGYNPMDLKRGMDLAVNAVVEEIKKSSKKINSQEEIAQVGTISSNGDKEIGEKIAKAMEEVGKEGVITVEEAKNFSFDVEVVKGMMFDRGYLSPYFVTNSEKMVAELENPFILLFEKKLSNLQPMLPILEAVVQSQRPLLIIAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMMEDIAILTKGELITEDLGMKLENVSIKSLGTAKRVTISKENTVIVDGNGDKKNIEDRVLQIKSQIAETTSDYDKEKLQERLAKLSGGVAVLKVGGATEVEVKERKDRVEDALAATRAAVEEGVVAGGGVTLLHASQPLTKLKVENKDQQAGIEIVIEALKDPLKQIVENAGENGGVVVGKLLEHKDKNYGFNAQDMQYVDMIKAGIIDPAKVVRTALQDAASVASLIITTETLIVDESSDKEEPMPMRGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCST_BURO0
Sequence: MTALNHTPLNAAHRALNARMVDFGGWDMPVNYGSQIEEHAAVRTDAGMFDVSHMCVVDFTGSRVRAFFEHAIANHVGKLKTPGKALYSCLLNPQGGVIDDLIVYYFTEEFFRVVVNAGTAEKDIAWFNQLNKQGGYGLTIAPRRDFAIVAVQGPNAREKVWATVPAARAATSELKPFNAAQVAGTPFGDLTIARTGYTGEDGFEVIVPAVHVEVLWNALQQHGVRPCGLGARDTLRLEAGMNLYGQDMDDTVSPLDAGLAWTVDLTAPRDFVGRAALEANGTRAAFVGLILQKENGKAGGVLRAHQKVVTPHGEGEITSGTFSPSMQESIAFARVPAAVQVGDIVQVQIRDKNLPARVVKLPFVRNGKVLAA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: BIOF_MYCA1
Sequence: MKAPIEVSPLAWLDAVEQQRRAAGLRRSLRPRPPVATELDLASNDYLGLSQHPDVIDGGVAALRLWGAGATGSRLVTGDTELHQQFESELADYVGAASGLLFSSGYAANLGAVVGLSGRGALVVSDAYSHASLVDACRLSRARVVVTPHRDVDAVLAALADRDEERAVVITESVFSTDGALAPLRELHEVCRRHRALLIVDEAHGLGVRGGGRGLVFEAGLAGAPDVVMTTTLSKALGSQGGAVLGPAAVRAHLIDAARTFIFDTGLAPAAVGAARAALGVLRAEPWRVGAVLRHAGVLAEVCRVREVPQSAVVSVILGDPDVAVAAATACLDAGVRVGCFRPPTVPAGTSRLRLTARASLDDAELEVARRVLTDVLAGLG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: DRS1_ASPOR
Sequence: MAPPKKRTAPKDDDFVLTLSDDENDVFSGINEDGDDHLDEETAKSTTKKRKRDTAETTQSKNKKQKQQKQSKNGKQQKKVEEAASEPEEGSEEEEDAGEDDGALNSDFEFDVGAAAQKDVVEGFDGWGLDETKDGAKKNGDKQGVDIDEIISRRQAKKEAQLKKKPKKQEVESEDEGSGNEDDASDGGMSVDFQDDELMAEDGFGMGADGEDESGQSDAQESGSEDEHAGSDSEDSDDDDDDAASDNDSVATPVQHPDDVASDNDGSDIESEVDAEEEAKRKAFFAPEEQTSEQSAAELSKKSFQEFNLSRPILRGLAAVNFTNPTPIQRKTIPVALLGKDIVGSAVTGSGKTAAFVVPILERLLFRPRKVPTSRVAILMPTRELAVQCYNVATKLATYTDITFCQLVGGFSLREQENILKKRPDVIIATPGRFIDHMRNSASFTVDTLEILVLDEADRMLEDGFADELNEILTTIPKSRQTMLFSATMTDSVDKLIRVGLNRPVRLMVDSKKNTSMNLIQEFVRLRPGREDKRLGYLLHLCKEVYTGRVIVFFRQKKEAHRVRIAFGLLGLKAAELHGSMSQEQRIRSVENFREGKVSFLLATDLAARGLDIKGVETVINYEAPQSHEIYLHRVGRTARAGRSGRACTIAAEPDRKVVKAAVKASKAQGAKVASRVVDPAVADRWAQKAKDLEEEINAVLEEEKIEKQLAQAEMQVTRSENMIKHEAEIMSRPKRTWFASEREKILSKKAGAAELNGLDSVKSKKEKVRLSNKDKKRLDDSRQRNEGNIGWKKGKVDRESQKQGKIQKGKKENKKKGKK
What is the function of this protein?
ATP-binding RNA helicase involved in ribosome assembly.
What are the official names of this protein?
ATP-dependent RNA helicase drs1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX27/DRS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ILVC_SHIDS
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLHDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: ATPE_ORYNI
Sequence: MKLNLYVLTPKRIIWDCEVKEIILSTNSGQIGVLPNHAPINTAVDMGPLRIRLLNDQWLTAVLWSGFARIVNNEIIILGNDAELGSDIDPEEAQQALEIAEANVSRAEGTKELVEAKVALRRARIRVEAVNWIPPSN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: NDHI_CUCSA
Sequence: MFPMVTGFMNYGQQTVRAARYIGQGFVITLSHANRLPVTIQYPYEKLIASERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQISLGRLPMSVVDDYTIRTILN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: VG22_BPT2
Sequence: KAEEEVEKNKEEAEEEAEKKIAE
What is the function of this protein?
Internal peptide VII: Cleavage product of Gp22 that is incorporated into the mature phage head.
What are the official names of this protein?
Major prohead-scaffolding core protein Gp22.
Protein: RK1_CYAM1
Sequence: MKRSKRYQSLCSLIEPKLYSPQEALKLLKKLATAKFVETAEAHIRLNLDPKYTDQQIRATVVLPHGTGKAIRIAVITKQSSHIEGADLVGSDDLCAQIAQSIINFDCLIATPDMMPTLAKLGKILGPRGLMPSPKSGTVTTNVAEAIQAFRRGQIEYRTDKTGIVHLAFGRMDFNEQHLYDNLVAIKESVETNKPSGASGLYWKSFAIATSMSPSIRLNIQQWS
What is the function of this protein?
Binds directly to 23S rRNA.  Might be involved in E site tRNA release (Potential).
What are the official names of this protein?
50S ribosomal protein L1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.