PharMolix/UniProtQA huggingface dataset:
Protein: RHAA_SALEP
Sequence: MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVAGFENPEGSLTGGIQSTGNYPGKARNATELRADLEQALRLIPGPKRLNLHAIYLESDTPVARDQIKPEHFKNWVEWAKANRLGLDFNPTCFSHPLSADGFTLSHPDAKIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLEALDEVISEKFDPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHNLFDRVHIGLDFFDASINRVAAWVIGTRNMKKALLRALLEPTDQLRQLEASGDYTVRLALLEEQKSLPWQAVWEMYCQRHDTPTGSQWLDSVRTYEKEILSKRS
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_CHLT3
Sequence: MLTNPRKKIRPGELNLKEKLVHINRTAKVVKGGKRFGFNAIVVVGDGEGHVGYGLGKANEVQDAIAKGIEDAKKNVIEVPIIKGTIPHQIFAKFGAAKVLMKPATPGTGLIAGGAVRAVLEMAGVKDVLTKSLGSSNPHNVVKATVHGLQEVSDAYDVSERRGKSLQDIYEG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: HBA_AILFU
Sequence: MVLSPADKTNVKSTWDKLGGHAGEYGGEALERTFASFPTTKTYFPHFDLSPGSAQVKAHGKKVADALTLAVGHLDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLACHHPAEFTPAVHASLDKFFSAVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: NADD_SYNJB
Sequence: MKHRRIAILGGTFNPVHHGHLIMAEQALWQFDLDQVLWMPAGDPPHKPLAPGASKADRLAMVKLAIADHERFACSELEIRRSGRSYTIETLRTLIQEQPNTQWYWIIGVDALRDLPQWYQAEELARLCHWIVAPRVDAGDAAQVLQAVAAKLPIQAQILEAPTLTLSSTYLRQQIQKGGSIRYLVPPAVEHYIRQHRLYLQP
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RK33_TOBAC
Sequence: MAKGKDVRVTVILECTSCVRNSVDKVSRGISRYITQKNRHNTPNRLELKKFCPYCYKHTIHGEIKK
What are the official names of this protein?
50S ribosomal protein L33, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UPP_SHEB2
Sequence: MKVVEVKHPLVRHKIGLMREGDISTKRFRELAAEVGSLLTYEATADFETETVTIEGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFEKLASDMNERIALVVDPMLATGGSMIATVDLLKKRGCTSIKALVLVAAPEGIKALEAAHPDIELYTAAIDKCLNEKGYILPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: NEK1_ORYSJ
Sequence: MEQYEVLEQIGKGAFGSALLVRHKVEKKKYVLKKIRLARQTDRTRRSAHQEMQLIATVRNPFIVEYKDSWVEKGCYVCIIIGYCEGGDMAEAIKRATGDHFSEEKLCKWLVQLLMALDYLHANHILHRDVKCSNIFLTRDQSIRLGDFGLAKILTSDDLASSVVGTPSYMCPELLADIPYGTKSDIWSLGCCIYEMTALRPAFKAFDMQALISKITKSIVSPLPTRYSGAFRGLIKSMLRKSPEHRPSAAELLKHPHLQPYVLQVHLKSSPARNIIPSHQSPIDKVKKMTFPTESMCRSKGRRNSLGNERIVTFSKPSPERKFTSSIQSIKDYSTTRSVKDLSIDVSLVEEVSSKTTFTTRTSSIVKTPKRTPSKTITTPQLEPPKVSYNRVNRSELLSRTPVNRSARVIRRASLPLPLPSSETPKRGVSSISILEQLESPDVSVNSPRIDRIAEFPLASSEDPPFLKLHGRRSPTPTPQHCVIDQSITKDKCMVEAFHIIDVDDDDGRSDSSSGRNNAAAAASSRAGSSESTRQRRFDTSSYQQRAEALEGLLEFSAQLLQQERYDELGVLLKPFGPEKVSPRETAIWLTKSFKETGL
What is the function of this protein?
May be involved in plant development processes.
What are the official names of this protein?
Serine/threonine-protein kinase Nek1, NimA-related protein kinase 1, OsNek1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.
Protein: SYR_SHESH
Sequence: MKSHIQSLLIQALDALKQQGVIPTDFEARVQVDRTKDKTHGDFATNLAMMLTKVARKNPRELAQLIIDSLPQDSQVAKVEIAGPGFINFFIDENALASQLMAALNDDHLGIQLPEPQTVVVDYSSPNLAKEMHVGHLRSTIIGDSVVRALEFQGHNVIRQNHVGDWGTQFGMLLAYMEELRAENGEQAQMELSDLETFYRAAKVRFDESEDFAIRARKLVVSLQSGDEYCNKLWREFNDISLSHCHDVYERLGVSLTRKDVRGESTYNDDLEQVVKDLDAKGLLSESNGAKVVFQDEFKTKDGDPLPVIIQKADGGYLYATSDLAAMRYRSNVLKADRALYFVDLRQGLHFQQVFKLARTAEFINPDMSLEHMGFGTMNGDDGRPFKTRSGGVVKLVDLLTEADTRALELVRSKNPDMDQAELEKIAKVVGISSVKYADLSKNRASDYIFSFEQMLSFEGNTAPYLLYAYTRVAGIFKRATDIDLSDAKMQLDHDKEKDLGNKLAQFGEVLSRMVTKGQPHALCGYLFELAGAFSSFYEACPVLAAESEEQKKSRLLLSQLTAKTLKQGLDLLGIETLERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAO1_YERPP
Sequence: MELEYESKRPLYIPYAGPILLEFPLLNKGSAFTNDERNHFNLHGLLPEAVETIEEQAERAYRQYQDFKNDDDKHIYLRNIQDTNETLFYRLLEAHLSEMMPIIYTPTVGEACEHFSDIYRRARGLFISYPNREHIDDMLQNATKQNVKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNPQRLNDPLYMGWRHPRISGDEYYAFVDEFIQAVKRRWPNVLLQFEDFAQKNATPLLNRYRDELCCFNDDIQGTAAVTLGSLIAASHAAGSQLRDQTVTFLGAGSAGCGIAEQIIAQMMSEGLSEIQARARIFMVDRFGLLTDKLPNLLDFQSKLVQKSDDLHHWNLHNDAISLLDVVRNAKPTVLIGVSGQPGLFTEELIREMHSHCARPIVMPLSNPTSRVEARPEDIINWTDGAALVATGSPFPPVSYKEKLYPIAQCNNSYIFPGIGLGVLASGASRVTDGMLMAASRALAESSPLARHGEGALLPNIDDIQAVSKAIAMRVGQAAQLQGVAIVTSEEALSKAIEHNYWQPQYRSYKRTSF
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: HIS1_NOSS1
Sequence: MLTVALPKGELLKNSIRLLQSVGLDFSAFLDSGNRQLQITDASGTAKGLLVRGQDVPVYVEYGQAQIGIIGYDVLREKQPQVAHLVDLQFGYCRMSVAVKASSPYKSPLDLPAHSRVASKYVNSAREFFQGLDLPVEIVPLYGSVELGPITGMSEAIVDIVSTGRTLKENGLVEITTLYESTARLIAHPLSYRLNTGNLHQLVEQLREGALTKV
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity).
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PO3F1_MOUSE
Sequence: MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGGTAHHLGPAMSPSPGAGGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGSASPPSAPPPPPPAALHHHHHHTLPGSVQ
What is the function of this protein?
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:1979677, PubMed:1976514).  Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (PubMed:18505825).  Acts as a transcriptional repressor of myelin-specific genes (By similarity).
What are the official names of this protein?
POU domain, class 3, transcription factor 1, Octamer-binding protein 6, Oct-6, Octamer-binding transcription factor 6, OTF-6, POU domain transcription factor SCIP.
What is the protein family that this protein belongs to?
Belongs to the POU transcription factor family. Class-3 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2393_ARCFU
Sequence: MGCICGHLQLLGCLRHCLNRNGGGTLVVAFAFTAFFSLLTILEVLSALNIFGGEGTLMNAFVLGTITATFAKGVVVRRDSYLFVASLLAAAFSVLMILVYMASGSFSYGIFGLVTVPYLVKKARK
What are the official names of this protein?
Uncharacterized protein AF_2393.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTU_ACIBS
Sequence: MTTTTTKFRDVEIRAPRGTELMAKSWLTEAPLRMLMNNLDPDVAENPKELVVYGGIGRAARNWECFDKIVDTLKNLETDETLLVQSGKPVGVFKTHKDAPRVLIANSNLVPHWANWEHFNELDAKALAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGDLKGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQASIDFRLRTRYVDEQATDLDDALARIDRYTKEGKAISIALHGNAAEILPELVRRGVRPDMVTDQTSAHDPLNGYLPVGWTWDEYRERAKKEPEAVVKAAKQSMAKHVQAMLDFQKMGVPTFDYGNNIRQMAKEEGVANAFDFPGFVPAYIRPLFCRGIGPFRWAALSGDPEDIYKTDAKVKELIPDDEHLHHWLDMARERISFQGLPARICWVGLGLRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSVASPNRETEAMQDGSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGVVIVCDGTDEAAARIARVLTNDPATGVMRHADAGYEIAINCAKEQGLHLPMITQ
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLR45_PLAVT
Sequence: MSIFIFISLVLGLAHQHKRSSIIVRLYSKDGFQKCSLTIRAVSAYALACKLQLEHRPLRAQRLRQIRLAQKSRVFPFIFYQCPHKKKSARIHALTFTKEAELSKLSIETLRCIHLQLISCTRSPVVTNSSY
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 45.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Accumulates at the margin of the nucleolus, but is absent within it.
Protein: P2RX1_HUMAN
Sequence: MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSGLISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLREAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVENGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
What is the function of this protein?
Ligand-gated ion channel with relatively high calcium permeability.  Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle.  Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).
What are the official names of this protein?
P2X purinoceptor 1, P2X1, ATP receptor, Purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the P2X receptor family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPPH_SALPK
Sequence: MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLLQLMSADAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMALQDNPPKLQSAPAYRRKRG
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: PAND_ACIBT
Sequence: MLSRLLKCKIHRAVVTHAELHYEGSCAIDGVLMDLAGIREYEEIHVWNVTNGKRFTTYAIRGEDNSGIISVNGGAAHQADVGDLVIIATFGDFTEAEANAHKPRLVYANPDNTVNHTANCIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVD_NEIMF
Sequence: MPEYRSKTSTHGRNMAGARALWRATGVMETDFGKPIIAVANSFTQFVPGHVHLHNMGQLVAREIEKAGAIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADALVCISNCDKITPGMLIAAMRLNIPTIFVSGGPMEAGKVIGVANIQPERRLDLIDAMIESADDNVSNRQVEEVEQNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSYLATHVGRKELFLEAGRMIVEITKRYYEQNDETVLPRSIATKKAFENAMTMDIAMGGSTNTILHLLAVANEAGVDFKMADIDRLSRVVPCICKTAPNNHDYYMEDVHRAGGIFAILKELDKAGKLHTDVHTIHAPTLKDAIEKWDITNPENTRAIERFKAAPGGVRTTQAFSQNRMWKTLDLDREKGCIRDVAHAYSQDGGLAVLFGNIAERGCVVKTAGVDESILKFTGRARVFESQEDAVEGILGNQIVAGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAEGGAIGLVHEGDTVEIDIPNRSIHLAISDEELAARRAEMEARGSKAWKPENRDRYVSAALRAYGAMATSADKGAVRDVAQIER
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: LCMT1_DEBHA
Sequence: MISPQEKQDKVIRATDLDALSCRYSANNKSYFSKPDPFIDSLISSYKMHLPLCTGYTNMSANRTLRSVFNEQKLPLINRGTYLRTESIDVITQEFIKEFKKCQVISLGGGSDTRCFRILEEHGEDVRYCEIDFHESVKIKKLAIINDKKLADIVKYDEESQSITSKEEFARLESNIHTENYHLIGYDLRELTGALDSGAILEYVDTSLPTLILSECVLCYLNPKENERIIEFWKNAFASKALLALLIYEPMSLNDAFGTTMTHNLSNRGINLLTFNEYPNLEARYKFLSEKCQSSNVKLTDMSNVGGYDSDNTTKAWINSKDLARINRLELVDEIEEIRLLLKHYCLCYCEFSHSPSLKTINKWKWILE
What is the function of this protein?
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
What are the official names of this protein?
Leucine carboxyl methyltransferase 1, Protein phosphatase methyltransferase 1, [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: ATG3_NEOFI
Sequence: MNILHSTLSTWRDRLAPVSRTSTFRTTGQITPEEFVLAGDYLVYKFPTWAWADASSPAKRVSYLPPGKQFLVTRGVPCHRRLNENFAGDAGHEDEIVRDMLSGADADDGDGWLRTGGGRDLAEKQAERIKDVRTVDESGNMGEREDDEEDIPDMEDDDDDEEAIIREPAGKSTTQPIRTYNLYITYSNFYRTPRLYLSGYLSPSEPLPPHLMMEDIVGDYKDKTVTLEDFPWFDGGLKMASVHPCRHASVMKTLLDRADAALKIRRDKLKQAHSAAEANRINSERGLEGLVDETRGLSLNEQQGHAAGGDEWEVLQHDEEDQVAIRVDQYLVVFLKFIASVTPGIEHDFTMGV
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt) and autophagy.  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of atg8.  The atg12-atg5 conjugate plays a role of an E3 and promotes the transfer of atg8 from atg3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of atg8.  The formation of the atg8-phosphatidylethanolamine conjugate is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  The atg8-PE conjugate mediates tethering between adjacent membranes and stimulates membrane hemifusion, leading to expansion of the autophagosomal membrane during autophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 3, Autophagy-related E2-like conjugation enzyme ATG3.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSD_CHLTE
Sequence: MRIAPYGTGSVVKTAIFCFVIFITALFLPQPGGVILATAALGFLLFTLYFYRDPERKIPDGKGLVIAPADGKIVLKQTLDHPVTGPGSTLVSIFMSPFNVHVNRIPVDGLVRDLRYHEGKFLMAFDHRSMTDNERMEITLDTAAGPLWFCQVSGFVARRIVCDLEAGQEVASGKRFGMIKLGSRVDIVLPSSIQIKVKEGMKTTAGETILGQTGGF
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LEU1_VIBCM
Sequence: MNNQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDIIEAGFPVSSPGDFESVQTIAKNIKNSRVCALSRAVAKDIDAAAEALKVAEAFRIHTFISTSTIHVQDKLRRSYDDVVAMAVKAVKHARQYTDDVEFSCEDAGRTPIDNLCRMVEAAINAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAIQAGARQVEGTINGIGERAGNCALEEIAMIIKTRQELLGVTTGIKHDEISRTSKLVSQLCNMPIQSNKAIVGANAFSHSSGIHQDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDSMGYNENEYNLDALYEDFLKLADRKGQVFDYDLEALMHFSNLREEDDFYKLNYLSVQSGSVMATTSIKLLCGGEEKCEAAVGNGPVDALYQCIYRITGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGVSTDIVEASGQALLHVINSIHRADQIAQIKQKKSVATV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: NU1M_XENLA
Sequence: MLTIITHLINPLLYMIPILLAVAFLTLIERKVLGYMQHRKGPNIVGPTGLIQPIADGVKLFIKEPVRPSTSSQTMFLIAPTMALALAMSIWAPLPMPFSLADLNLGILFILALSSLAVYTILGSGWSSNSKYALIGALRAVAQTISYEVTLGLILLCMIMLAGGFTYTTLMTTQEQMWLIIPGWPMAAMWYISTLAETNRAPFDLTEGESELVSGFNVEYAGGPFALFSLAEYANILMMNTLSYLILFLGSSFMNQPELTTISLMIKSSILSMIFLWVRASYPRFRYDQLMHLVWKNFLPITLAMTLWHISLPISMLGLPSQT
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OS25_PLAFO
Sequence: MNKLYSLFLFLFIQLSIKYNNAKVTVDTVCKRGFLIQMSGHLECKCENDLVLVNEETCEEKVLKCDEKTVNKPCGDFSKCIKIDGNPVSYACKCNLGYDMVNNVCIPNECKNVTCGNGKCILDTSNPVKTGVCSCNIGKVPNVQDQNKCSKDGETKCSLKCLKENETCKAVDGIYKCDCKDGFIIDNESSICTAFSAYNILNLSIMFILFSVCFFIM
What are the official names of this protein?
25 kDa ookinete surface antigen, Pfs25.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: YTFE_YERPS
Sequence: MDYRNQSLGALAIAIPRATKLFRQHQLDFCCGGKQTLLRAANKLNLDIDALEAQLSALQTEPHSSEDWQQQPLTNLISFIISRYHDRHREQLPELVLMAEKVERVHGDKPTCPRGLAAELSAILEELTQHMYKEEQILFPMIQRGMGSQASGPIFVMEAEHDAVGQQLDVVKQLTQNVTPPEGACNTWRALYTGINEFITDLMEHIHLENNLLFPRALRGE
What is the function of this protein?
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions.
What are the official names of this protein?
Iron-sulfur cluster repair protein YtfE.
What is the protein family that this protein belongs to?
Belongs to the RIC family. YtfE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_ECOSM
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: LPXZ_PORGI
Sequence: MQKQQTLKDKFCLQGKGLHTGLDIHITFCPAPEESGYKIKRVDLEGQPVIDAIADNVHSTRRGTVLKKGEVSVSTIEHAMAALYALGVDNCLIEVDAPEFPILDGSAEPYVSEIKRVGLVEQETPRDYYIIKKRMEVSDPESNSKLILLPDDEFTVDVHIAFPSKVLSNQFASLETLSDFEEQIAGARTFVFVREVQMLLEANLIKGGDLDNALVIYDEPLAQDRLDALSDMMGVERKQVNELGYINNKPLIYDNEPARHKLLDVLGDLALIGKYIRGRIIATCPGHSINNKMARLIRKEIKQNEAQAPVYNPNKEPIMDINRIKELLPHRYPFLLVDKIIEVGPDYIVGVKSVSGNEPFFPGHFPGEPVMPGVLQVEAMAQVGGLLVLNTLTEPSSYSTYFLMIDKVKFRRKVVPGDTLVFKLRMISEIRRGVANMRGLAFVGEQLACEAEFMAQIIQNKE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
Bifunctional enzyme LpxC/FabZ.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thioester dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBPC1_CAEEL
Sequence: MPSDSDDVAAVKQPWSQLIVDISNFLSEHPQSKTSQALLPSCNGVWSDEEKLELIEAFGHKKQSHLTKSGVKAVLAAFEGDRTQPDVIFLCRLLHLIFSHFSSENDRKKEKYIVKCDVIATLTRITRKRIIMTLDVTDESSIDHNLDEVLWKLLHKIGLKDPRVSLKVRMGGLISPMCKLFIQKDTLPELFLPFFIKISRSPRNGQAIGRYEGFMTRLLVKIKALDASDQTSQVLLLDKHLQLLFFTMKNKRTRTQLLRENICKYLLEVLRRHLASSSNSRPTRLLSSLFGTFDKSLSAAHTEVVIGTIAILRLLSNFKKARDELKNLQVLDICSRELKEFWSDEWKTGPKSRIVDSLSALCLRCMSPLPYPLETRRFPIDFPLPTATPSTPGGHGRIRNSSSINISFDNGRSSDEDGMDEEDEAFVRDDDDEGKDDRGSDDDDGKDDDEINGALPKTTRLNPQQLAKYAPFFVENEQGTLQPTFSMIYQTNQESWRSICEKTRHVMPIHHHLPIEMFNTPTRIREKTAKTSNNMKKMIIEELDKPERSATSNQVIYDLDTAAFDGLPSPELPFVTGGGKLDTSKDLQFDSRFESGNLRMVIQVAPTHYELFLSPDVNQLRDHYQWFFFQVSNMRKSVKYTFEIVNCLKSTSLYSQGMQPVMYSMMESANGWRRVGENVCYFRNLYINENEEKKNVEEQKKKKYYYSIRFNVTFQNTGDICYIAYHYPYTYSFLNSSLSMLKKRKQENVYCREDVIGHSLAGNPIKMLTITTPASAAEIAAREVIVLSARVHPGETNASWIMQGILENLLCRQSNEMYRLRESFIFKIVPMINPDGVTNGSHRCSLAGIDLNRMWDRPNEALHPEVFATKAIIQYLCEVANKKPFAYVDIHGHSKKWDYFVYGNNASESWRADDVLDVGAAQLEEELHLALPKALEATCPSRFNASECRFNITRAKESSARVNVWRQFGVSTAYTLESTFCGFHKGQNSGYQINTSDLKEIGRDLLHSFLEMTKT
What is the function of this protein?
Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation of proteins such as tubulins (Probable).  Via the deglutamylation of tubulin, regulates the localization and velocity of kinesin motors and the structural integrity of microtubules in sensory cilia (PubMed:21982591, PubMed:29129530).  In male CEM sensory neurons, regulates the cilia release of bioactive extracellular vesicles (PubMed:29129530).  Also regulates microtubule dynamics in uterine muscle cells (PubMed:24780738).
What are the official names of this protein?
Cytosolic carboxypeptidase 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Perikaryon. Cell projection, cilium. Cell projection, dendrite.