PharMolix/UniProtQA huggingface dataset:
Protein: SECA_LEGPL
Sequence: MLSTLIKKMFGSRNERTLRRMEKSVMAINAFEPKMQALSNEELAGKTQEFKERFNNGESLDELLAEAFATVREVSLRTLGLRHFDVQLIGGMVLHEGNIAEMRTGEGKTLVATLPAYLNAISGRGVHIVTVNDYLAKRDSQWMKPIYEFLGLTVGVIYPDMSHKEKQEAYKADIVYGTNNEYGFDYLRDNMAFSLTDKVQRELNFAIVDEVDSILIDEARTPLIISGAAEDSSELYIKINSLIPQLKKQEEEGDEGDYTIDEKQKQAHLTDAGHLHIEELLTKAKLLDPGESLYHASNIMLMHHVNAALKAHAMFHRDIDYIVKDNQVVIVDEHTGRTMPGRRWSEGLHQAVEAKEGVSIQNENQTLASITFQNFFRMYNKLSGMTGTADTEAYEFQQIYNLEVVVIPTNRSMIRKDEADLVYLTQADKFQAIIEDVRECGVRRQPVLVGTVSIEASEFLSQLLKKENIKHQVLNAKFHEKEAQIIAEAGRPGAVTIATNMAGRGTDIVLGGSLAADLANLPADASEQEKEVVKKEWQKRHDEVIAAGGLRIIGSERHESRRIDNQLRGRAGRQGDPGSSRFYLSLEDNLMRIFASERVGSMMRRLGMQPGEPIEHSLVTRAIENAQRKLEGHHFDVRKQLLDYDNVANDQRQVIYTQRSSIMAMTDTQEVVEMMREEVMDSLVDTYIPPQSLEDQWDPQALSDVLSDEFKIKAPVPDWIDKDHSIQPEQIKEKILALAIEHYDEKVRKVGRPVISQFEKSIILQTLDNHWREHLAAMDQLRQGIHLRGYAQKDPKQEYKKEAFSLFTMMLDNLKYEVIRILSSVEIQTEEDAHVVEEQRRAEQIKKMNLMHENLSENDEASETQTFRRQEKKIGRNDPCPCGSGKKYKACHGSLV
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: TRPC_AGRVS
Sequence: MSDILKKIEAYKREEIAAAKNAVPLDEIKARAADQPPARGFYKALRAKQAAGNFGLIAEIKKASPSKGLIRPDFDPPALASAYEAGGAACLSVLTDAPSFQGAPDFLVAARAACTLPALRKDFMFEAYQVHEARAWGADCILLIMASLSDSEATDLEGEALALGMDVLIEVHDEEEMLRALKLASPLVGINNRNLRTFEVDLAVSERLAAMVPADRLLVGESGIFTHEDCLRLQKSGIETFLVGESLMRKDDVTGATKALLTGASDRIAAE
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: MUTL_SHESR
Sequence: MGIQILPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIEIDKGGSKLIKIRDNGSGIPKDELALALSRHATSKLHSLDDLEAILSFGFRGEALASISSVSRLTLTSRTAEQTEAWQAYAEGVDMAVKVMPAAHPVGSTIEVVDLFFNTPARRRFLKSDKTEFTHIDEWLKRIALVRGDIHFTLTHNGKTVRNYRPAMNEPQYLQRLTQVAGRQFADEALRVECQHDDLRLSGYLQSPWSTVLTDTHYFYVNGRLVRDRLVNHAVRQAFAQKAEVEQPGYVLMLDIDPHQVDVNVHPAKHEVRFHQSRYVHDYILQALQSALEEAGELGFERPFEPSSPQVRDEVSLSESGAQTQTEHHAFELQSPESKTHSTWDEASRVDTSRAEISRDSSLGERTRDIASTRPYAGVQSNAYGSMAVPRESRSGSTGESRARAELPSKVAIASYGELLQTPSYNVQDKPYQPVLAMPAILNGQYWVLAQEQNLSLLPIQSVALATRSHEIETKLATGLIGQPLLMPVSIAADTDWPALLEEHETLIRQLGLELTIRYQQLIIKKVPPYLRDSQLAKVIPEWLQSLRFEAPAPNALAVWLAEQSLTGFTSAADIWAAYCQLTEEKRQQIADKAVSLPWQSWLEEQAIE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: GRPE_BURL3
Sequence: MENTQENPATQSAEDIGSEKQAAQGAAPAAEAADAALAEAQAKVAELQESYLRAKAETENVRRRAQDDVSKAHKFAIEGFAEHLLPVLDSLEAAVNDTSGDITKVREGVELTLRQLTNALEKGRVVALNPVGEKFDPHQHQAISMVPAEQEPNTVVTVLQKGYTIADRVLRPALVTVAQPK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_MESFL
Sequence: MSYIQKQGKNTAWRVALMRNLTSELIVSERLEITETRAKELRKHLDKMVTLAKRGDLHARRQAASWLRNIEASSKEDVLQKLFTTIAKKYKDRDGGYTRILKLDNRKGDNAPMVIIELV
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: PIMT_SALPK
Sequence: MVSGRVQALLEQLRAQGIRDELVLNALAAVPREKFIDEAFEHKAWENIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVHHVCSVERIKGLQWQARRRLKQLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMAQLDEGGILVLPVGDEQQFLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATA_STRPI
Sequence: MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFVTIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFDATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAVASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTVKENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKETILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDATNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFADYDLILGPTAPSVAYDLNSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVGLQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: Y2001_TRIV2
Sequence: MASTYSFDIVSDFDRQELVNAVDQVIRDLKSRYDLKDTQTTVELGEEKITIGTDSEFTLESVHNILREKAAKRNLSQKIFDFGKVESASGNRVRQEITLKKGISQDIAKQISKLIRDEFKKVQASIQGDAVRVSAKAKDDLQTVIQRLKQEDYPVALQFTNYR
What are the official names of this protein?
UPF0234 protein Ava_2001.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: RNP4_HYPBU
Sequence: MSGSKAKSRELARDVALQAIRTLYLAAVDAVRRGDYELARRLVAEADETRRVMRLRKPRFLRRGVCRNCSLPLVPGVTARYRLVRDGSVTRLVVTCLACGYIHRHVLVQRRRGSR
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 4, RNase P component 4, Rpp21.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRD3_YEAST
Sequence: MITLLLYLCVICNAIVLIRADSIADPWPEARHLLNTIAKSRDPMKEAAMEPNADEFVGFYVPMDYSPRNEEKNYQSIWQNEITDSQRHIYELLVQSSEQFNNSEATYTLSQIHLWSQYNFPHNMTLAHKYLEKFNDLTHFTNHSAIFDLAVMYATGGCASGNDQTVIPQDSAKALLYYQRAAQLGNLKAKQVLAYKYYSGFNVPRNFHKSLVLYRDIAEQLRKSYSRDEWDIVFPYWESYNVRISDFESGLLGKGLNSVPSSTVRKRTTRPDIGSPFIAQVNGVQMTLQIEPMGRFAFNGNDGNINGDEDDEDASERRIIRIYYAALNDYKGTYSQSRNCERAKNLLELTYKEFQPHVDNLDPLQVFYYVRCLQLLGHMYFTGEGSSKPNIHMAEEILTTSLEISRRAQGPIGRACIDLGLINQYITNNISQAISYYMKAMKTQANNGIVEFQLSKLATSFPEEKIGDPFNLMETAYLNGFIPAIYEFAVMIESGMNSKSSVENTAYLFKTFVDKNEAIMAPKLRTAFAALINDRSEVALWAYSQLAEQGYETAQVSAAYLMYQLPYEFEDPPRTTDQRKTLAISYYTRAFKQGNIDAGVVAGDIYFQMQNYSKAMALYQGAALKYSIQAIWNLGYMHEHGLGVNRDFHLAKRYYDQVSEHDHRFYLASKLSVLKLHLKSWLTWITREKVNYWKPSSPLNPNEDTQHSKTSWYKQLTKILQRMRHKEDSDKAAEDSHKHRTVVQNGANHRGDDQEEASEILGFQMEDLVTMGCILGIFLLSILMSTLAARRGWNVRFNGAQLNANGNRQQEQQQQQQAQGPPGWDFNVQIFAI
What is the function of this protein?
Component of the endoplasmic reticulum quality control (ERQC) system involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Component of the HRD1 ubiquitin ligase complex, which is part of the ERAD-L and ERAD-M pathways responsible for the rapid degradation of soluble lumenal and membrane proteins with misfolded lumenal domains (ERAD-L), or ER-membrane proteins with misfolded transmembrane domains (ERAD-M).  ERAD-L substrates are ubiquitinated through HRD1 in conjunction with the E2 ubiquitin-conjugating enzymes UBC1 and UBC7-CUE1.  Ubiquitinated substrates are then removed to the cytosol via the action of the CDC48-NPL4-UFD1 ATPase complex and targeted to the proteasome.  ERAD-M substrates are processed by the same HRD1-HRD3 core complex, but only a subset of the other components is required for ERAD-M.  Stabilizes the HRD1 ubiquitin-protein ligase.  Also functions in recruiting misfolded protein substrates in conjunction with YOS9.
What are the official names of this protein?
ERAD-associated E3 ubiquitin-protein ligase component HRD3, HMG-CoA reductase degradation protein 3.
What is the protein family that this protein belongs to?
Belongs to the sel-1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: FTHS1_STRSV
Sequence: MVLSDIEIANSVQMKSIKEVAEKLGIAEDALSLYGNYKAKISAGQLEALKDKPDGKLILVTAISPTPAGEGKTTTSVGLVDALAAIGKKAVIALREPSLGPVFGIKGGAAGGGHAQVVPMEDINLHFTGDFHAIGVANNLLAALIDNHIHHGNALGIDSRRITWKRAVDMNDRQLRHIVDGLQGKVNGVPREDGFDITVASEVMAILCLSENITDLKNRLEKIIIGYSFEGKPVTAKDLKAGGAMAAVLKDAIHPNLVQTLEHTPALIHGGPFANIAHGCNSVLATKLALKYADYAVTEAGFGADLGAEKFIDIKCRTSGLRPAAVVLVATIRALKMHGGVAKSDLAEENVQAVVDGLPNLEKHLENIQDVYGLPAVVAINKFPLDTEAELQAVYDACQKRGVDVVISDVWANGGAGGKELAEKVVELAEGDNHFQFVYNEEDSIETKLNKIVTKVYGGKGVRLTPAAKRELKQLDELGFSNYPICMAKTQYSFSDDAKKLGAPKDFVVTISQLKVSAGAGFIVALTGAIMTMPGLPKVPASEKIDVDKDGNISGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase 1, Formyltetrahydrofolate synthetase 1, FHS 1, FTHFS 1.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: LGT_STAXY
Sequence: MLTLNYIDPIAFELGPISVRWYGIIIAAGILLGYFIAQASVKKIGYDQDTLVDIIFWSAIFGFIVARIYFVIFQWPYYIQNPIEIPMIWHGGIAIHGGLIGGFVTGIIICKQKNINPFQIGDVIAPSMILGQGIGRWGNFMNHEAHGGPISRSVLENLHIPNFIIDNMYIDGKYYQPTFLYESLWDILGFVILILLRKHLRVGDTFCLYLIWYSIGRFFVEGMRTDSLMLTSDIRVAQLMSIILILIGVIIMIIRRVKYRSPRYKDVGPLSWPNPKVK
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: C3H33_ARATH
Sequence: MDFNAGVPMSSLSPLMNQDAMWQMNLSSDETMETGSYPERPGEPDCSYYIRTGLCRFGSTCRFNHPRDRELVIATARMRGEYPERIGQPECEYYLKTGTCKFGVTCKFHHPRNKAGIAGRVSLNMLGYPLRSNEVDCAYFLRTGHCKFGGTCKFNHPQPQPTNMMVPTSGQQSYPWSRASFIASPRWQDPSSYASLIMPQGVVPVQGWNPYSGQLGSVSPSGTGNDQNYRNLQQNETIESGSQSQGSFSGYNPGSSVPLGGYYALPRENVFPERPGQPECQFYMKTGDCKFGTVCKFHHPRDRQAPPPDCLLSSIGLPLRPGEPLCVFYTRYGICKFGPSCKFDHPMRVFTYDNTASETDEVVETSTGKSRRLSVSETRQAATTSSGKDTTIDNTQQ
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 33, AtC3H33, Zinc finger CCCH domain-containing protein ZFN1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNY_CUTAK
Sequence: MLIALIAVSVLAVAAIIGSLADRRAIGRRAERAESERDVKALELSRSQERLSRASQDLADSRKDVAKARAELESSRTRASDEARRADNADQARRSAEALLEINRRSVEELTERDHRLQEARRHLEEGLDKIEQDRLELAERSSQLDERDAELDRRHGQIVTELERVAGMSLDEARDELVEHLGREARVFAENSARAIVTEATASAEAKARHIVAEVIQRCSSEMVADTVVSVVPLPSNEMKGRVIGREGRNIRTFEQVTGVTVIIDDTPEIVLLSCFDPMRREVARQALTDLVEDGRIHPISIERAHQRAVDRIEDMCLDAAADALSRAGIDDIDDRLLPILGSLRFRTSYGQQVLDHCVECARLAANLAAEIGADIEICRRAAFLHDLGKSLTPGVEGSSHAAIGAELARRYGESEEVIHAIAAHHDEIDPVSVTDFIVKAADAISAARPGARRESLEAHVRRMDTIEEIATSFPGVVRAFALQAGREMQILVDPGAVDDHQASRLARQIALAIGEQVTVPGRTRVTVIRSFQAIETVGDA
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: DNAJ_LEIXX
Sequence: MADHYEVLGVERNATPDEIKKAYRRLARELHPDVNPSTEAQERFKLVTHAYDVLSDPQQRQQYDRGGASGFGGGGGADFSGFGDIFETFFGGGGASRGPRSRRERGQDALLRVEVDLDEVVFGAHRDLEVDTAIVCETCDGSCCQPGTAPVPCDICHGTGSIQRSVRSLLGNVMTSSPCGSCRGYGTVIATPCVTCQGQGRVRARRTVPVDIPAGVDTGLRLQMPGSGEAGPAGGPNGDLYLEIKVKHHDVFSRDGDDLLCTLEVSMADAILGAAATIKALDGDIRLELKPGTQSADIVSVKDRGITHLRCSGRGDLRVGIQVVTPTKLDHREKELIKKFAESHKASEPSLARFQQGLFAKLRDRFLNV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTL_CHLPN
Sequence: MSTRRPIQLLDPLTINQIAAGEVIENSVSVVKELIENSLDAGADEIEIETLGGGQGAIIIRDNGCGFRAEDIPIALQRHATSKIREFSDIFSLNSFGFRGEALPSIASISKMEIQSSIEGDEGVRTVIHGGDIVSCEPCARQLGTTVIVNSLFYNVPVRRGFQKSMQSDRLGIRKLIENRILSTANIGWSWISEGHHEIQIAKQQGFQERVAYVMGDHFMQDALTIDKEANGVRIVGVLGSPSFHRPTRQGQKIFINDRPIESLFISKKVGDAYALLLPLHRYPVFVLKLYLPSSWCDFNVHPQKIEARILKEELVGDCIKEAIVETLACPPGILCRTHQEIEESDSVPLPMFRMLETSDVQEEESVEFDQNLFAYSSEDVSLEKQEYTSRGPKSQMDWIYSSDVRFLTSLGRVVLAEDLEGVHIIFTAAARKHLFFLSLMQENSRMYQSQALLIPLRLQVTPEEAFFFSHHGRTLCDLGIEISQVGPCVFSIESTPTVIGEEELKEWLLLLAARGSTDINSEALTALMKETLTQATFSKHQHVFDVSWLKLLWSVGKPEKGFDGARIRRLILDSDFMEG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity).
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ISPF_SYNC1
Sequence: MMRIGHGYDVHQLVAERKLILGGVDIPHTLGLLGHSDADVLLHAICDAILGALGEGDIGKHFPDTDPAYKGISSIKLLHEVMRLAETKGYRLGNLDATIIAQRPKLAPFIGNMRENIAEACGTDVSRINVKATTTEQLGFEGRGEGISSHAVVLLNKAAHSEER
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: LPXK_ANADE
Sequence: MSGLEAIWWRERPGPLGALAGAPLLLAEAPFRAAAALRGALYDRGLLPAARAGAPVVSIGNLAVGGAGKTPAALAVAARLAGRGRRVAILSRGYGAARADARVASDGAGALLPAAEAGDEPALLARRLPGVAVLCGPRRAELARTAVESLGADALVLDDGFQHRALARDLDVVVLDASNPFGNGHLLPRGPNREPPSALRRAGLVWLSHADRAAPERLEALRALARDATGRAPVESRHAPTALLDGALREAGALEALRGRRVAALSGLARPAGFLRTLEALGAEVALARAFPDHHRFTAGELDAVLREAAASGCAWVVTTEKDAVRLDPALAAAAGDRLRVVRVDAELLRGADVLEAALAAALAAAPQPRPAPRAPVA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: HIS7_RHOBA
Sequence: MTSSNSNSSREVSLERKTGETDIKLSVNLDGSGAGKRDSGIGFLDHMLDLLAKHALIDLTVEAKGDLHVDDHHTAEDIGIALGTAVDRALGDRAGVRRYGHFTLPMDECLVTSAVDMGGRYAFEYNAPIAASKIGTFDSELVEHFWQSFAVNAKCNLHVLLHHGSNGHHISECVFKATARAIRMAVESDPRSDAIPSTKGVL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_BORDL
Sequence: MKKKNLITAALPYVNNIPHLGNLVQVLSADAFARYSRMMGIETLYVCGTDEYGTATETKALIEKTTPEELCNKYHAIHKSIYEWFNIKFDIFGRTTNKYHKETVQDLFLKLDKNGYITEKENEQFFCQQDKMFLADRYVTGECPNCGNNTKGDQCENCSNLLVTNELLNPRCIICKNIPIIKKTKHLYIDLPKIKNELEHWIQQIDQNTNWNTNAIKITNAFLRDGLKERTITRDLKWGIPVPKKEYENKVFYVWFDAPIGYISITKEIIKDWESWWKNNEDTNLIQFIGKDNILFHTIMFPSIELGSQENWTMLNKLASSEYLNYENLKFSKSAGTGIFGNDVITTGIPSDVWRFYIYYNRPEKADFQFMWDDFMERINSELIGNFSNLINRVLTFYKKFFGDKIDKIELNENFWQIVNIKYERTINFFKQIELKAALKEILDISRIGNKIFQDKEPWKTKNSTPQTTKELLLNLIYLIRDLSILISPFMPHTSDRIRSFFGKSYEISNKFLGTNLGLTTIQSTEVLFTKIEKQLIDSLKLKYSGRTNMQDEQNKNSINLFSEQICLKTVKIKTIDRNPDAEKLFILKLDDGTPEGKQIVSSIADHYTEEELIGKHIIIVDNLKPAKFRGIRSEGMLIATEDENKNFKIIIVEDFKDNPIPGERVILESDTGKELKSPTKINIDKFLQAQIVAENGELKINGINLILEHSKEKVLSKEIPNGKIY
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CC022_HUMAN
Sequence: MDSSACKKSHQSKKWRIQAQENFAKKFPYRLSWLTEPDPEPLQPWEVTNDSNTVQLPLQKRLVPTRSIPVRGLGAPDFTSPSGSCPAPLPAPSPPPLCNLWELKLLSRRFPRQLAFLLSTRHTEAACPQTSKAAGLSRGLS
What are the official names of this protein?
Uncharacterized protein C3orf22.
Protein: CISY_TETNG
Sequence: MSFLTVNRLASKLLNSKNATYFLVAARNASASTTNLKDVLADLIPKEQNRIKNFKQQYGKTNIGQITVDMVYGGMRGMKGLVYETSVLDPDEGIRFRGYSIPECQKLLPKAAGGQEPLPEGLFWLLVTGQVPTEEQVNWVSKEWAKRAALPSHVVTMLDNFPTNLHPMSQFSAAVTALNSESSFARAYSEGVHKSKYWEFAYEDSMDLIAKLPCIAAKIYRNLYREGSSIGAIDSGLDWSHNFTNMLGYSDAQFTELMRLYLTIHSDHEGGNVSAHTSHLVGSALSDPYLAFSAAMNGLAGPLHGLANQEVLVWLTALQKELGGEVSDEKMRDYIWNTLKSGRVVPGYGHAVLRKTDPRYSCQREFAMKHLPNDPMFKLVAQLYKIVPDVLLEQGKAKNPWPNVDAHSGVLLQYYGMTEMNYYTVLFGVSRALGVLSQLVWSRALGFPLERPKSMSTDGLMSLVGAKSG
What are the official names of this protein?
Citrate synthase, mitochondrial, Citrate (Si)-synthase.
What is the protein family that this protein belongs to?
Belongs to the citrate synthase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: UBIC_YERPG
Sequence: MFIGDASILKPIQWCATEHPELPADIADWLMELGSMTRRFEQHCQRVHVEPQRECFITRDALGEEAEHLPVSQRYWLREIVLFGDNVPWLLGRTVIPEETLSGPDRALVDLGTLPLGRYLFSGDALTRDYIHVGRQDNLWARRSLLRLSGNPLLLTEVFLPASPLYTHCDSIPK
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_BACSU
Sequence: MPKMKTHRGSAKRFKKTGSGKLKRSHAYTSHLFANKSQKQKRKLRKSAVVSAGDFKRIKQMLANIK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: AROK_METM5
Sequence: MRCSAVSLGSGTIINAIATGFGSAFGVDLKIKADVELVDNCKKIINGISIDNPTLKPSLVERCVKNVLDHFEVDYSAKISTSGDIPIKSGLSSSSAASNAAVLATIGALGEKVDSDLVLDLAIKSSFEEKLTITGAYDDATASYFGGITVCNNMERKILKKDEFKEDIKVIVLMPEFQKNVDVNRMKLIKDYVEIAFEKCMEGDYYKALFLNGLLYSSALNFPSNISVDALEAGAITAGLSGTGPSYVALCYSEDKKNVENALKKYGNTVITKPSTNGARILY
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIS_ECOLI
Sequence: MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRASLFMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLRNDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV
What are the official names of this protein?
Flagellar secretion chaperone FliS.
What is the protein family that this protein belongs to?
Belongs to the FliS family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: TR11B_BOVIN
Sequence: MNKLLCCALVFLDISIKWTTQETFPPKYLHYDPESSRQLMCDKCPPGTFLKQPCTARRKTVCAPCPDHYYTDTWHTSDECLYCSPVCKELQYVKQECSRTHNRVCECEEGRYLELEFCLKHRSCPPGFGVLHPGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNCSAFGLLLTQKGNATHDNICSGSSESSTHKCGIDMTLCEEAFFRFAVPTKLTPNWLSVLVDNLPGTKVNAESIERIKQRHNSREQTFQLLKLWKHQNKDQDMVKKIIQDIDLCENSVRRHIGHLNLTFEQLLKLMESLPGKKVTTEDVEKTVKTCKSSEQLLKLLSLWRIKNGDQDTRKGLLHALKHLKTYHFPKTVIQSLKKTIRFLHSFTMYRLYRKLFLEMIGNQVQSLKISCL
What is the function of this protein?
Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.  Inhibits the activation of osteoclasts and promotes osteoclast apoptosis.  Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B.  May also play a role in preventing arterial calcification.  May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis.  TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 11B, Osteoprotegerin.
What are the subcellular locations of this protein?
Secreted.
Protein: RS20_GEOSE
Sequence: MANIKSAIKRAKTSEK
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20, BS20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: HIS7_STRM5
Sequence: MTPILFIDRDGTLIEEPSDFQIDAYEKLRFVPQVIPALLKLRDAGYQFVIVTNQDGLGSDSYPRASFDGPNELMLQIFESQGITFRDVLIDCSWPQDNAPTRKPGIGLMTAYLQDRSIDWARSGMVGDRITDLQFAENLNIRGFQLRTEQFGGEWDWPGIAHALADAPRIAVVQRDTKETKIRVELDLDRAGDARIDTGLPFFDHMLEQIGKHGGFALDIQAEGDLHIDEHHTIEDTGLALGQALREALGDKRGIGRYGFTLPMDETLASAALDFSGRPYFVFEGEFKRERVGDMPTELVPHFFRSLCDASGLNLNLQVRGDNDHHKVEACFKALARALRPALARQGTALPTTKGAL
What are the official names of this protein?
Histidine biosynthesis bifunctional protein HisB.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.