PharMolix/UniProtQA huggingface dataset:
Protein: FDB28_GIBM7
Sequence: MTQEIRTVAIVGCGVIGMGWAVLFLSRGLKVIISDPMEGAENALKGYFEQSRSYLEGFGDYDKLVSNYEFVHDIASRLAEADLIQENGPERLEFKRGLIATLDKYARPGVVIASSSSGLPSSEFIQQCKQDSTRVLIGHPFNPPHLIPLVEVVPHPGTSSESVNTALNFYRSVGKRPILLHHEVPGFVSNRLQAAINNEAYSLISRGIVSAEDLDAAVTSGPGLRWALTGPIATNALGGGGGPEGFSQRMERLGPAIRGWEDDILKHRFDWSEQRMSALQESVNKSLGAVKWDQLVEERDLVLLQLLAAKQKMASMSTPSGH
What is the function of this protein?
3-hydroxyacyl-CoA dehydrogenase; part of the Fusarium detoxification of benzoxazolinone cluster 2 (FDB2) involved in the degradation of benzoxazolinones produced by the host plant (PubMed:19302487, PubMed:26808652).  Maize, wheat, and rye produce the 2 benzoxazinone phytoanticipins 2,4-dihy-droxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) and 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA) that, due to their inherent instability once released, spontaneously degrade to the more stable corresponding benzoxazolinones, 6-methoxy-2-benzoxazolinone (MBOA) and 2-benzoxazolinone (BOA), respectively (PubMed:11876429).  The first step in the detoxification of benzoxazolinones involves the hydrolysis of the cyclic ester bond of benzoxazolinones by the FDB1 cluster gamma-lactamase MBL1 to aminophenols (PubMed:26808652, PubMed:12788712).  MBL1 is able to convert BOA into 2-aminophenol (2-AP), as well as MBOA into 5-methoxy-2-aminophenol (2-AMP) (PubMed:26808652, PubMed:12788712).  The FDB2 cluster N-malonyltransferase FDB2/NAT1 then metabolizes aminophenols via N-malonylation to non-toxic malonamic acids (PubMed:19302487, PubMed:12788712).  FDB2/NAT1 converts 2-AP into N-(2-hydroxyphenyl) malonamic acid (HPMA) and 2-AMP into N-(2-hydroxy-4-methoxyphenyl) malonamic acid (HMPMA) (PubMed:19302487, PubMed:12788712).  The duplicated dienlactone hydrolases DLH1 and DLH2 may provide redundant function for hydrolyzing the lactone moiety in the BOA molecule (Probable).  The roles of the amidases an other enzymes encoded by the 2 FDB clusters have not been identified so far (Probable).
What are the official names of this protein?
3-hydroxyacyl-CoA dehydrogenase FVEG_12628, Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12628, FDB2 cluster protein FVEG_12628.
What is the protein family that this protein belongs to?
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: EIF3I_DROMO
Sequence: MLQGHERSITQIKYNREGDLLFSCSKDQKPNVWYSLNGERLGTYDGHQGAVWCLDVDWETRKLITGAGDMTTKIWDVEYGTVIASIAAKSSVRTCNFSFSGNQAAYSTDKAMGQNCELFIIDVRNADSSLSEQAPTLRIPMVESKITSMLWGPLDETIITGHDNGNIAIWDIRKGQKVVDSGSDHTAGINDMQLSKDGTMFVTASKDTTAKLFDSESLMCLKTYKTERPVNSAAISPILDHVVLGGGQDAMEVTTTSTKAGKFDSRFFHLIYEEEFARLKGHFGPINSLAFHPDGKSYASGGEDGFVRVQTFDSTYFENIFE
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit I, eIF3i, Eukaryotic translation initiation factor 3 subunit 2, TRIP-1 homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit I family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C17_RAT
Sequence: MTTTIRQFTSSSSIKGSSGLGGGSSRTSCRLSGSLGAGSCRLGSASGLGSALGGNSYSSCYSFGTGSGYGGNFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQKQAPGPARDYSAYYQTIEDLKNKILVATVDNASILLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAAPGVDLSRILSEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGSLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQNQEYKILLDVKTRLEQEIATYRRLLEGEDAHLTQYKPKEPVTTRQVRTIVEEVQDGKVISSREQVHQTTR
What is the function of this protein?
Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair.  Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state.  Modulates the function of TNF-alpha in the specific context of hair cycling.  Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway.  Involved in tissue repair.  May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial 'stem cells'.  Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors.  May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
What are the official names of this protein?
Keratin, type I cytoskeletal 17, Cytokeratin-17, CK-17, Keratin-17, K17, Type I keratin Ka17.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CM3C_CONST
Sequence: RHGCCKGPKGCSSRECRPQHCC
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  This synthetic peptide reversibly inhibits the brain sodium channel rNav1. 2/SCN2A (IC(50) is 40 nM) and the skeletal muscle sodium channel rNav1. 4/SCN4A (IC(50) is 9 nM).
What are the official names of this protein?
Mu-conotoxin SIIIC, Mu-conotoxin TIIIA-like.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MYG_STRCA
Sequence: MGLSDQEWQQVLTIWGKVESDIAGHGHAILMRLFQDHPETLDRFEKFKGLTTPEQMKASEELKKHGVTVLTQLGKILKQKGKHEAELKPLAQTHATKHKIPVKYLEFISEVIIKVIAEKHSADFGADSQAAMKKALELFRNDMASKYKEFGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: KATG_SALPK
Sequence: MSTTDDTHNTLSTGKCPFHQGGHDRSAGAGTASRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYSALKGDLKALLTDSQPWWPADWGSYVGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWADLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAAAASHVGADPEAAPIEAQGLGWASSYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPDIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAFNEAFARAWFKLTHRDMGPKARYIGPEVPKEDLIWQDPLPQPLYQPTQEDIINLKAAIAASGLSISEMVSVAWASASTFRGGDKRGGANGARLALAPQRDWEVNAVAARVLPVLEALQKTTNKASLADIIVLAGVVGIEQAAAAAGVSISVPFAPGRVDARQDQTDIEMFSLLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTVLVGGMRVLGTNFDGSQNGVFTDRPGVLSTDFFANLLDMRYEWKPTDESNELFEGRDRLTGEVKYTATRADLVFGSNSVLRALAEVYACSDAHEKFVKDFVAAWVKVMNLDRFDLL
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: GREA_SOLM1
Sequence: MESIPISVEGFRRLERELERLKKERPGVILAIKEAREEGDLRENAGYEAARERQGMLEARINYIESRMSRFNVIDLATLGGEQVIFGATVEIEDVDTGDVKKYTLLGPDEAEPSKGSISLLSPVGLALLGKFVGDEIVVDAPRGKINYEIVSIAFHGPIAAADD
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: Y026_SYNPW
Sequence: MAGFGLPNFGQLTEAFRKAQQIQQDAQKLQEELDAMEIEGSSEDGRASIWLSGNQQPLRVKLDPSLLNEGQDTAEAAVLAALQSAYERSTATMKERMQDLTGGLDLNLPGMGG
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SynWH7803_0026.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: IF2A_METTH
Sequence: MFFMVRRKNEWPEEGELVVGTVHKVLNYGAFATLEEYPGKEAFIHISEVSSGWVKNIRDFVRENQKIVARVLRVNPRKGHVDVSMKRIREDQRTKKIQAWKIEQKAEKFLELAARDLGKDLDTAYEEVGYELMDIFGDLYGAFETAAEEGEKSLIEEGVPEDWAAVITEVAKRNITPPEVQITGYVDIKSYAPNGVEIIRKALKSAQDEGITVQAVGAPRYRLIVKSTDYLKAEKQLKEAAQKCIEIVEKEGGEGEFLRELT
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit alpha, aIF2-alpha, eIF-2-alpha.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-alpha family.
Protein: PANE_YERPE
Sequence: MKITVLGCGALGQLWLSMLHQQDHDVQGWLRVPQPFCSVNVIMLNGESFNRNLTTNDPKHLLQSELLLVCLKAWQVSSAVTALLPKLNPECKILLLHNGMGTQEELPLNEHVFLHGVTTHAARRDGNTIIHVASGMTHIGPTSSVIIDDNHLADTLHQALPDVAWHNDISAACWQKLAVNCVINPLTGLYNCRNGDVQRYPELIERLCAEVASVMEMEGYHTSTESLLSYVNNVIRSTADNTSSLLQDLRSQRHTEIDYITGYLLRRARSHGMALPENARLYELIKRKESDYERIGAGLPGSW
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HORM2_CANLF
Sequence: MATAQLSHSIKIHKASKETVFPSQITNEHESLIMVKKLFATSISCITYLRGLFPESSYGERHLDDLSLKILREDKKCPGSLHIIKWIQGCFDALEKKYLHMAVLTLYTNPKEPEKVTEIYQFKFKYTKEGATMDFDSYSSSASFESGTNSEDIKKASILLIRKLYILMQNLGPLPNDVILTMKLHYYNAVTPHDYQPPGFKEGVNSHLLLFEGEPVNLQVGLVSTGFHSMKVKVTTEVTRVSDLENNLFQENSTTEIAHQGLDFDEEEEECNNHVRQSCSESPLIASVKKKRKKDFPIYFFYEFRK
What is the function of this protein?
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity.  Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes.  Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
What are the official names of this protein?
HORMA domain-containing protein 2.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the male and female prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes (By similarity).
Protein: GRPE_RHILO
Sequence: MSDQAKDERAPSEAEAAEANAERTEGSIDGDYEALVRLLKENEELKDRALRVAAEMENLRRRTARDVHDARTYAVANFARDMLSVSDNLRRALDAIPAEAKASGDAGFKALIEGVDLTERAMLSALERHGVKKLAPEGEKFDPNFHQAMFEVPNPDVPANTVVQVVQPGYSIGERVLRPAMVGVAKGGPKIAAEAPVEPGPVNEQAEKDA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_CLOK5
Sequence: MQLNMLKSKIHRATVTEANLNYVGSITIDRELMESAHIIEYEKIQVVDIDNGNRLETYVIAGEKGSKVICLNGAAARHVQPGDKVILMTYCQMDEEEAKIHKPIVIFLDENNSIFQITDYEKHGQVK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACB_STRPB
Sequence: MKIAVGCDHIVTYEKIAVVDYLKSQGHKVIDCGTYDNVRTHYPIFGKKVGEAVASGEAELGVVICGTGVGITNAVNKVPGIRSALVRDMTSAIYSKEELNANVIGFGGKIIGGLLMNDIIDAFLAAEYKPTEENKKWIEKMDSLQHASQDQNNPHFFDEFLEKWDRGEYHD
What are the official names of this protein?
Galactose-6-phosphate isomerase subunit LacB.
What is the protein family that this protein belongs to?
Belongs to the LacAB/RpiB family.
Protein: PAX8_XENTR
Sequence: ELITERGCSGPASNLNIGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSKILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDNDTVPSVSSINRIIRTKVQQLFNLPMESCVKSLSPGQTLIPSSAVTPPESPHSDSLGSTYSISGLLGITQPGADGKRKLDDSDQESCRLSIDSQGSMGISRKQLRTEAYGHHPLDALECHFQRQHFPESYSSSTHSKTEQALYTLPLLNNAMDDGKSSLTSTNTTIGRNLSTHQGYSALSELSAFTIKQEASDSSSASSTPSSLCSPTFLDLQPISSGCSAPSFSAFSHPASVYGQFTSHMASGRDVVGSTLPGYPPHIPSGQGNYASSAIAGMVAAGGDYSGNAYSHGAYAAYGESWRFPSSSLLGSPYYYSSATRTAPPPTTAGAYDLL
What is the function of this protein?
Probable transcription factor.  Involved in kidney development, acting synergistically with lhx1/lim-1 to establish the pronephric primordium in late gastrulae/early neurulae (By similarity).
What are the official names of this protein?
Paired box protein Pax-8.
What are the subcellular locations of this protein?
Nucleus.
Protein: SY124_ARATH
Sequence: MNDLFSSSFKKYTDLKQQAQMDDIESGKETMNLDKFFEDVENVKDNMKGVETLYKSLQDSNEECKTVHNAKKVKELRAKMDGDVAQVLKRVKMIKQKLEALEKANANSRNVSGCGPGSSTDRTRTSVVSGLGKKLKDLMDSFQGLRARMNAEYKETVERRYFTITGEQADEQTIENLISSGESENFLQKAIQEQGRGQILDTISEIQERHDAVKEIEKNLIELHQVFLDMAALVESQGQQLNDIESHVSKASSFVRRGTDQLQDAREYQKSSRKWTCYAILLFIVVFALLLIPALPHIMLMLK
What is the function of this protein?
Vesicle trafficking protein that functions in the secretory pathway.
What are the official names of this protein?
Syntaxin-124, AtSYP124.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: ELBA1_DROME
Sequence: MINRRQRLEFALTLLPYDPETVQLSETQKKVEAIIARLRTDDSFTEEESDDCKVRRIQDANEFADSAMRHIEMSDSGKLSTLETLTLAAEKLLRTQRSPDQDFDDMVQDVEYSQLMRNTIQAVNEARLKLLQQWERSKRKALDLLTIEIEKVQEMDQEPEHKQSHEQDQDQEQSSEPFNAFRDGADEHNTSTPKTNDEDLGLDDDDEDYVPGGEETMGNKRKRIKKPVTSTPNAKRRCPGFEFDLDGESPMVTIGPNGTEVSRISLSAINWDMTGPSITRKLLCEIFDRDTLAHHTLSGKPSPAFRDCARPSKQQLDPLKVADLVYLMTNSLDMTPREVRTAITTKCADENKMLRSRMQRKSK
What is the function of this protein?
The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis.  It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity (PubMed:23240086).  Elba1 may act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression (PubMed:25561495).
What are the official names of this protein?
Early boundary activity protein 1, Blastoderm-specific gene 25A.
What are the subcellular locations of this protein?
Nucleus.
Protein: CNN_DROME
Sequence: MNSNRTSSSHNSRNLKILNASFDVPRPPGGGNSPLPSQGRSVRELEEQMSALRKENFNLKLRIYFLEEGQPGARADSSTESLSKQLIDAKIEIATLRKTVDVKMELLKDAARAISHHEELQRKADIDSQAIIDELQEQIHAYQMAESGGQPVENIAKTRKMLRLESEVQRLEEELVNIEARNVAARNELEFMLAERLESLTACEGKIQELAIKNSELVERLEKETASAESSNEAIDSLKVELEACRKENQDLVTSIRTLKHDMKRQVRSMKEAANTMDVQRQSILLLEATIKRKEKSCGSMQKNVLNYEALIAKLNAELETMRQQNVYFRELSENLQQKEVRQLDRGVAIVQPMRMTADAGRFVWQSGTIVAQEPLPLERQSAAATSNVSVSAVRLSSGPPPDQTYPVNGHDRAKYGLLQLFAAKLDWISAVPLALGHLALKIILLAMRLHSCLQNVHIPLRANRDLGAQLADKICELQEAQEKLKERERIHEQACRTIQKLMQKLSSQEKEIKKLNQENEQSANKENDCAKTVISPSSSGRSMSDNEASSQEMSTNLRVRYELKINEQEEKIKQLQTEVKKKTANLQNLVNKELWEKNREVERLTKLLANQQKTLPQISEESAGEADLQQSFTEAEYMRALERNKLLQRKVDVLFQRLADDQQNSAVIGQLRLELQQARTEVETADKWRLECVDVCSVLTNRLEELAGFLNSLLKHKDVLGVLAADRRNAMRKAVDRSLDLSKSLNMTLNITATSLADQSLAQLCNLSEILYTEGDASHKTFNSHEELHAATSMAPTVENLKAENKALKKELEKRRSSEGQRKERRSLPLPSQQFDNQSESEAWSEPDRKVSLARIGLDETSNSLAAPEQAISESESEGRTCATRQDRNRNSERIAQLEEQIAQKDERMLNVQCQMVELDNRYKQEQLRCLDITQQLEQLRAINEALTADLHAIGSHEEERMVELQRQLELKNQQIDQLKLAHSTLTADSQITEMELQALQQQMQEIEQLHADSVETLQSQLQKLKLDAVQQLEEHERLHREALERDWVALTTYQEQAQQLLELQRSLDYHQENEKELKQTLVENELATRALKKQLDESTLQASKAVMERTKAYNDKLQLEKRSEELRLQLEALKEEHQKLLQKRSNSSDVSQSGYTSEEVAVPMGPPSGQATTCKQAAAAVLGQRVNTSSPDLGIESDAGRISSVEVSNAQRAMLKTVEMKTEGSASPKAKSEESTSPDSKSNVATGAATVHDCAKVDLENAELRRKLIRTKRAFEDTYEKLRMANKAKAQVEKDIKNQILKTHNVLRNVRSNMENEL
What is the function of this protein?
Core component of the centrosome throughout spermatogenesis.  May participate in mitotic spindle assembly and the mechanics of morphogenesis through an interaction with microtubules, either directly or indirectly.  Is a target of several homeotic genes.
What are the official names of this protein?
Centrosomin, Protein arrow.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, flagellum basal body. Note=Localized to the centrosomes through complete nuclear cycles in mitotic and meiotic cells. Redistributed into the cytoplasm in G2 phase cells. In post-meiotic stages, found associated with the basal body of the maturing spermatid.
Protein: HOL24_BPSPP
Sequence: MEQMRQDIIELKQNDKSQEQRISLLERTSDRHDQQIQAVTESLSKIHENTTWIKRTITGAIISTLSTVVVGGILTIVWNLVKN
What is the function of this protein?
Probably functions as a holin together with holin-like protein 26.  Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space.  Determines the precise timing of host cell lysis.
What are the official names of this protein?
Holin-like protein 24.1, Gene product 24.1, gp24.1.
What are the subcellular locations of this protein?
Host cell inner membrane; Single-pass membrane protein.
Protein: GATB_PSEP1
Sequence: MQWEVVIGLEIHTQLATQSKIFSGSATTFGSEPNTQASLVDLGMPGVLPVLNEEAVRMACMFGLAIDAEIGKRNVFARKNYFYPDLPKGYQISQMDLPIVGKGHLDIALEDGTIKRIGVTRAHLEEDAGKSLHEDFSGSTGIDLNRAGTPLLEIVSEPDMRSAKEAVAYVKAIHALVRYLGICDGNMAEGSLRCDCNVSIRPKGQTEFGTRCEIKNVNSFRFIERAINSEIQRQIDLIEDGGKVVQETRLYDPNKDETRSMRSKEEANDYRYFPDPDLLPVVIEDSFLETIRAGLPELPPQKVERFQTQYGLSAYDANVLASSREQADYFEEVVKIGGDAKLAANWVMVELGSLLNKLGVEIDQAPVSAAQLGGMLLRIRDNTISGKIAKTVFEAMAAGEGDADSIIESKGLKQVTDTGAIDKMLDEMLAANAEQVEQYRAADEAKRGKMFGFFVGQAMKASKGKANPGQVNQLLKAKLEG
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: ASSY_MAGMM
Sequence: MSNGIDKVVLAYSGGLDTSIILKWLQDEYQCEVVAFCADLGQAEELEPARAKAEKFGVKEIYIDDLKEEFVRDFVFPMYRANTLYEGVYHLGTSIARPLIAKRQIEIANATGAQAVSHGATGKGNDQVRFELGYYALRPDIRVIAPWREWDLTSRDKLFAYAEKHGIPVPTDKRGEVPYSMDRNLLHISFEGKALEDPWVEPDEEMFVLSVSPEKAPDQATYVELTFRQGDLVAIDDQEMSPATLLAKLNQLGGRNGIGRLDLVENRYVGMKSRGVYETPGGTILGVAHRAMESLTLDREVAHMKDELMPRYAKLIYNGYWFSPERAMLQTMIDASQTFVNGKVRVKLYKGNVVVVGRQSENSLFDPAIATFEDDKGAYNQADADGFIKLNALRMRIAAMLRNGPKV
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA2_SYNC1
Sequence: MPFRIAFLKQPFEDFFKHQASGGIVLLGATVLALVLANSPWSGQYFHFWEIKLTIGFDHFGLTQTLHHWINDGLMAVFFFLVGLELKREFMDGELASFRQAMLPIAAAFGGMLVPALIFHFINPMVPEAKGWGIPMATDIAFALGVLALLRGKISRSLAIFLTALAIVDDLGAVLVIALFYSGELAVGKLLVALVLLLILIAGNRLGVQSLNFYGLLGFCLWVVLLKSGLHASIAGVLIGMVIPARPRLCHEEFVDQTEKYMARYKEIGEVPGPFHHEERLGALLALEHICHDAMSSLQRMEHELHHWVIFGVIPIFALANAGLVLQLGNLVTAVTHPVTLGVALGLLLGKPLGILFFSWISVRVGLCALPRGTSWMDVFGVGILGGIGFTMSLFISNLAFMNIVMSNNAKLGIFIASMLAGAAGFTVLSRASARKAH
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RLUF_SHIFL
Sequence: MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDIVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPILGTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSSSEAKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR
What is the function of this protein?
Dual specificity enzyme that catalyzes the synthesis of pseudouridine from uracil-2604 in 23S ribosomal RNA and from uracil-35 in the anticodon of tRNA(Tyr).
What are the official names of this protein?
Dual-specificity RNA pseudouridine synthase RluF, 23S rRNA pseudouridine(2604) synthase, Ribosomal large subunit pseudouridine synthase F, rRNA pseudouridylate synthase F, rRNA-uridine isomerase F, tRNA(Tyr) pseudouridine(35) synthase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RsuA family.
Protein: LIN32_CAEEL
Sequence: MSWEQYQMYVPQCHPSFMYQGSIQSTMTTPLQSPNFSLDSPNYPDSLSNGGGKDDKKKCRRYKTPSPQLLRMRRSAANERERRRMNTLNVAYDELREVLPEIDSGKKLSKFETLQMAQKYIECLSQILKQDSKNENLKSKSG
What is the function of this protein?
Probable transcription factor which binds the E box motif 5'-CA[TC][AG]TG-3' (PubMed:11076762).  Essential for the specification of the neuroblast cell fate in the development of peripheral sense organs (PubMed:7800042).  Its role in the generation of sensory neurons may be through positively regulating the expression of the zinc finger protein ztf-11 during postdeirid neurogenesis (PubMed:31386623).  Required for specification of cell fate, acting in concert with lin-32, in the development of the male-specific genital sensilla (simple sense organs) known as rays (PubMed:11076762).  Involved in regulating glial specification, perhaps by suppressing a glial fate in different lineages during early embryogenesis (PubMed:32665354).
What are the official names of this protein?
Protein lin-32, Abnormal cell lineage protein 32.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL10_SALPK
Sequence: MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRVVEGTQFECLKDTFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.