PharMolix/UniProtQA huggingface dataset:
Protein: FABH_HAEDU
Sequence: MYSKILATGSYLPKQVRSNADLEKMVDTTDEWIFTRSGMKERRIAAADETVATMGAAAAHKACEMAAIDVNEIELIVVATTTHSHAYPSAACQIQGMLAIEDAIAFDVAAACTGFIYALSVADQFIRAGKVKTAFVVGADVNSRVLDEADRGTVVLFGDGAGAVILQASEQAGILSTHLHSSADTDNMLALPIQERGNAQSGFIQMQGNATFKLAVSRLANVVEETLQANNLQKADLDWLVPHQANIRIIAATAKKLEMEMSQVVLTVEKYGNNSAATVPVALDEAVRDGRIQRGQLLLLEAFGGGWTWGSGLVRF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX2_MARPO
Sequence: MNLIWIFPIAFCDAAEPWQLGFQDPATPMMQGIIDLHNDIFFFLIVILIFVLWMLVRALWHFHYKRNPIPERIVHGTTIEIIWTIFPSIILMFIAIPSFALLYSMDEVVDPAITIKAIGHQWYWTYEYSDYNSSDEQSLTFDSYMIPEDDLELGQLRLLEVDNRVVVPAKTHLRMIITSADVLHSWAVPSLGVKCDAVPGRLNQTSIFIKREGVYYGQCSELCGTNHGFMPIVVEAVSLDDYVSWVSNKLD
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: THYX_PYRHO
Sequence: MVKVKLINYTPKPLETVTWAALISYWDGWSTEAFEKISPNDVEIHLPRILSYGHESILEHATFTFSIEGCSRVCTHQLVRHRIASYTQQSQRYIKINPEDVEETFVIPESIKKDSELLKEWKELLKRSLELYEKSIERGIHQEDARFILPQSVKTKIVVTMNLRELKHFFGLRLCERAQWEIREVAWKMLEEIAKRKELKPIIEWAKLGPRCIQLGYCPERELMPPGCLKRTRERWKNLLEKY
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: ADHB_CLOAB
Sequence: MVDFEYSIPTRIFFGKDKINVLGRELKKYGSKVLIVYGGGSIKRNGIYDKAVSILEKNSIKFYELAGVEPNPRVTTVEKGVKICRENGVEVVLAIGGGSAIDCAKVIAAACEYDGNPWDIVLDGSKIKRVLPIASILTIAATGSEMDTWAVINNMDTNEKLIAAHPDMAPKFSILDPTYTYTVPTNQTAAGTADIMSHIFEVYFSNTKTAYLQDRMAEALLRTCIKYGGIALEKPDDYEARANLMWASSLAINGLLTYGKDTNWSVHLMEHELSAYYDITHGVGLAILTPNWMEYILNNDTVYKFVEYGVNVWGIDKEKNHYDIAHQAIQKTRDYFVNVLGLPSRLRDVGIEEEKLDIMAKESVKLTGGTIGNLRPVNASEVLQIFKKSV
What are the official names of this protein?
NADH-dependent butanol dehydrogenase B, BDH II.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: CMOA_ACTP2
Sequence: MNKDTIFSAPIEKLGDFTFDESVAEVFPDMIQRSVPGYSNIITAIGMLAQRFVTEGSQVYDLGCSRGAGILSIRRNLQTNQVKIIGVDNSQPMVERCRSHINAYHSEVPVEILCDDIRHIEIKNASMVVLNFTLQFLPRADRLELLTKIYQGLNPNGILVLSEKFTFENQVMNELLIDLHHTFKRANGYSELEVSQKRTALENVMLTDSIETHKDRLKQAGFSQIELWFQCFNFGSMIAVK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: NANE_SHIFL
Sequence: MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLALVKTLSEAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: RL15_PYRHO
Sequence: MIRRRKKVRKLRGSHTHGWGCKKKHRGGGSKGGRGMAGTGKRNKSKWTWTIKYAPDHLGKRGFSRPPEVQRDVRIVTLKFIDEHLEDLLQMGIAYEEEGKIVVDTTQFADKVLGTGRLTRPLTIKAKAFSAKAEEKIKAAGGEVILA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RIMM_PROM0
Sequence: MINKNEWLTVGLITSCHGINGQVKVKSLSDFEERFLKPGMRWLQKENEPPSKIELISGFKQPGKETFIVKLQGINTRNDAEQLKTFKILVRTDKLPKLKKEEFHLLELINLEVKTLENDELKTIGKVINLENEKNNLLIIELFKNQKKVLIPFVKEIVPLVDIKNQFVIINPPNGLLEL
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CP3AS_BOVIN
Sequence: MELIPSFSMETWVLLATSLVLLYIYGTYSYGLFKKLGIPGPRPVPYFGSTMAYHKGIPEFDNQCFKKYGKMWGFYEGRQPMLAITDPDIIKTVLVKECYSVFTNRRIFGPMGIMKYAISLAWDEQWKRIRTLLSPAFTSGKLKEMFPIIGQYGDMLVRNLRKEAEKGNPVNMKDMFGAYSMDVITGTAFGVNIDSLNNPHDPFVEHSKNLLRFRPFDPFILSIILFPFLNPVFEILNITLFPKSTVDFFTKSVKKIKESRLTDKQMNRVDLLQLMINSQNSKEIDNHKALSDIELVAQSTIFIFGGYETTSSTLSFIIYELTTHPHVQQKLQEEIDATFPNKAPPTYDALVQMEYLDMVVNETLRMFPIAGRLERVCKKDVEIHGVTIPKGTTVLVPLFVLHNNPELWPEPEEFRPERFSKNNKDSINPYVYLPFGTGPRNCLGMRFAIMNIKLALVRILQNFSFKPCKETQIPLKLYTQGLTQPEQPVILKVVPRGLGPQVEPDFL
What is the function of this protein?
Cytochromes P450 are a group of heme-thiolate monooxygenases.  In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway.  It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
What are the official names of this protein?
Cytochrome P450 3A28, CYPIIIA28.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: TGA9_ARATH
Sequence: MANHRMSEATNHNHNHHLPYSLIHGLNNNHPSSGFINQDGSSSFDFGELEEAIVLQGVKYRNEEAKPPLLGGGGGATTLEMFPSWPIRTHQTLPTESSKSGGESSDSGSANFSGKAESQQPESPMSSKHHLMLQPHHNNMANSSSTSGLPSTSRTLAPPKPSEDKRKATTSGKQLDAKTLRRLAQNREAARKSRLRKKAYVQQLESSRIKLSQLEQELQRARSQGLFMGGCGPPGPNITSGAAIFDMEYGRWLEDDNRHMSEIRTGLQAHLSDNDLRLIVDGYIAHFDEIFRLKAVAAKADVFHLIIGTWMSPAERCFIWMAGFRPSDLIKILVSQMDLLTEQQLMGIYSLQHSSQQAEEALSQGLEQLQQSLIDTLAASPVIDGMQQMAVALGKISNLEGFIRQADNLRQQTVHQLRRILTVRQAARCFLVIGEYYGRLRALSSLWLSRPRETLMSDETSCQTTTDLQIVQSSRNHFSNF
What is the function of this protein?
Together with TGA10, basic leucine-zipper transcription factor required for anther development, probably via the activation of SPL expression in anthers and via the regulation of genes with functions in early and middle tapetal development (PubMed:20805327).  Required for signaling responses to pathogen-associated molecular patterns (PAMPs) such as flg22 that involves chloroplastic reactive oxygen species (ROS) production and subsequent expression of H(2)O(2)-responsive genes (PubMed:27717447).
What are the official names of this protein?
Transcription factor TGA9, Protein TGACG (TGA) motif-binding protein 9, bZIP transcription factor 21, AtbZIP21.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACPH_BOVIN
Sequence: MERQVLLSEPEEAAALYRGLSRQPALSAACLGPEVTTQYGGRYRTVHTEWTQRDLERMENIRFCRQYLVFHDGDSVVFAGPAGNSVETRGELLSRESPSGTMKAVLRKAGSTGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDISGSDDEMARPKKPDQAIKGDQFLFYEDWGENMVSKGSPVLCVLDIESGNISVLEGVPESVSPGQAFWAPGDTGVVFAGWWHEPFRLGIRFCTNRRSALYYVDLTGGNCELLSDDSLAVTSPRLSPDQCRIVYLQFPSLVPHQQCGQLCLYDWYTRVTVVVVDVVPRQLGENFSGIYCSLLPLGCWSADSQRVVFDTAQRSRQDLFAVDTQMGTVTPLTAGGSGGSWKLLTIDRDLMVAQFSTPNLPPCLKVGFLPPAGMEQEVVWVSLEEAEPIPDISWSIRVLQPPPEQEHAQYVGLDFEAILIQPSNPPDKTQVPMVVMPHGGPHSSFVTSWMLLPAMLCKMGFAALLVNYRGSTGFGQDSILSLPGNVGSQDVKDVQFAVEQVLQEEHFDAGRVALLGGSHGGFLSCHLIGQYPETYGACVVRNPVINIASMMGSTDIPDWCVVEAGYLYSSDCLPDPNVWSEMLNKSPIKYTPQVKTPVLLMLGQEDRRVPFKQGMEYYRALKARNVPVRLLLYPKSTHSLSEVEVESDSFMNAVIWMCTHLGH
What is the function of this protein?
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus (PubMed:8375399).  It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser (By similarity).  Also, involved in the degradation of oxidized and glycated proteins (By similarity).
What are the official names of this protein?
Acylamino-acid-releasing enzyme, AARE, Acyl-peptide hydrolase, APH, Acylaminoacyl-peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RHAD_ECOLC
Sequence: MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_DESVV
Sequence: MPTINQLIRKERKKVVKRKKTPALQACPQRRGVCTRVYTTTPKKPNSALRKVARVRLTNGLEVTAYIPGEGHNLQEHSVVMIRGGRVKDLPGVRYHIVRGTLDTSGVQDRRQGRSKYGAKRPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: SYE2_EHRRW
Sequence: MLNHVVTRFAPSPTGHLHLGGARTALFNWLYAKHNNGKFLLRIEDTDSKRSSKELIDSIINSMIWLNIQHDGDIILQSSRISRHIEIANQLILNDKAYYCYCSEEEINLEKEEYTKKGLHYKHNCIWKNRNPPIGNCSKVIRLHSDTEGITEFKDKVYGTIAVNNVQLDDMVLLRSNNTPTYLLSVVVDDYDMGITHIIRGTDHLTNTARQLLIYNALGWKPPEFAHIPLIHDENGNKLSKRHHALGIHEYKNAGILPEALLNYLLRMGWSHGNDEVITIDEAIRWFSIDKVGQSPARLDSKKLEFLNNHYINATNNATIIEMIIPIIEKTIGYKVNTEKIGYLLNGINELKKRTKNLVNLANESLFYVEDIPISFDQESLIIIKSNHDILSILYDNLSKVLNDDWNNSTLTSMIKNIVKDYNTKIHNIYHCLRASIIGRINAPSIIDIMVNFQREECLNRIKYARDMVK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YMGG_SHIF8
Sequence: MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNGVNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVIGGTGGAILGKMK
What are the official names of this protein?
UPF0757 protein YmgG.
What is the protein family that this protein belongs to?
Belongs to the UPF0757 family.
Protein: ADT2_PONAB
Sequence: MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRHFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFALVLYDEIKKYT
What is the function of this protein?
ADP:ATP antiporter that mediates import of ADP into the mitochondrial matrix for ATP synthesis, and export of ATP out to fuel the cell (By similarity).  Cycles between the cytoplasmic-open state (c-state) and the matrix-open state (m-state): operates by the alternating access mechanism with a single substrate-binding site intermittently exposed to either the cytosolic (c-state) or matrix (m-state) side of the inner mitochondrial membrane (By similarity).  In addition to its ADP:ATP antiporter activity, also involved in mitochondrial uncoupling and mitochondrial permeability transition pore (mPTP) activity.  Plays a role in mitochondrial uncoupling by acting as a proton transporter: proton transport uncouples the proton flows via the electron transport chain and ATP synthase to reduce the efficiency of ATP production and cause mitochondrial thermogenesis.  Proton transporter activity is inhibited by ADP:ATP antiporter activity, suggesting that SLC25A5/ANT2 acts as a master regulator of mitochondrial energy output by maintaining a delicate balance between ATP production (ADP:ATP antiporter activity) and thermogenesis (proton transporter activity).  Proton transporter activity requires free fatty acids as cofactor, but does not transport it.  Probably mediates mitochondrial uncoupling in tissues that do not express UCP1.  Also plays a key role in mPTP opening, a non-specific pore that enables free passage of the mitochondrial membranes to solutes of up to 1. 5 kDa, and which contributes to cell death.  It is however unclear if SLC25A5/ANT2 constitutes a pore-forming component of mPTP or regulates it (By similarity).  Acts as a regulator of mitophagy independently of ADP:ATP antiporter activity: promotes mitophagy via interaction with TIMM44, leading to inhibit the presequence translocase TIMM23, thereby promoting stabilization of PINK1 (By similarity).  As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation (By similarity).
What are the official names of this protein?
ADP/ATP translocase 2, ADP,ATP carrier protein 2, Adenine nucleotide translocator 2, ANT 2, Solute carrier family 25 member 5.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=May localize to non-mitochondrial membranes.
Protein: AMPN_LACLC
Sequence: MAVKRLIETFVPENYKIFLDIDRKTKKIKGQVAITGEAKDTVVAFHAKGLHFNKVRAFSVDTNFIENEEDEEIVVKIGETGRVTVSFEYEAELTDNMMGIYPSYYEVNGEKKMLIGTQFESHFARQAFPSIDEPEAKATFDLSVKFDEEEGDIIVSNMPELLNINGIHVFERTVKMSSYLLAFVFGELQYKKGKTKSGVEVGAFATKAHSQAALDFPLDIAIRSIEFYEDYYQTPYPLPHSWHIALPDFSSGAMENWGCITYREVCMLVDPENATIQSKQYVATVIAHELAHQWFGDLVTMQWWDDLWLNESFANNMEYVCMDALEPSWNVWESFSISEANMALNRDATDGVQSVHVEVTHPDEIGTLFDPAIVYAKGSRLMVMLRKWLGDEDFAAGLALYFKRHQYGNTVGDNLWDALAEVSGKDVAAFMHSWVNQPGYPVVTAEVVDDTLILSQKQFFVGEGVDKGRLWNVPLNTNWTGLPDLLSSEKVEIPGFAALKTKNNGKALFLNDANMAHYIIDYKGALLTDLLSEVESLENVTKFQILQDRKLLAKAGVISYADVVNILPSFTNEESYLVNTGLSQLISELELFVDEDSETEKAFQSLVGKLFAKNYARLGWDKVAGESAGDESLRGIVLSKTLYSENADAKTKASQIFATHKENLASIPADIRPIVLNNEIKTTNSAELVKTYRETYIKTSLQEFKRELEGAVALIKDEKVIAELLESFKNADIVKPQDIAFSWFYLLRNDFSQDAAWAWEKANWASLEEKLGGDMSYDKFVIYPGNTFKTADKLAEYKAFFEPKLENQGLKRSIEMAIKQITARVALIDSQKAAVDKAITDIAEKL
What is the function of this protein?
Aminopeptidase with broad substrate specificity to several peptides.  It has more affinity for oligopeptides than for dipeptides.  It plays an essential role in the metabolism, it may be involved in nitrogen supply or protein turnover (By similarity).
What are the official names of this protein?
Aminopeptidase N, Alanine aminopeptidase, Lysyl aminopeptidase, Lys-AP.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
What are the subcellular locations of this protein?
Cytoplasm. Note=It may be secreted through an unknown mechanism.
Protein: LEUC_SHESH
Sequence: MAKTLYEKVWDSHVVVENEGQAPLIYVDRHLVHEVTSPQAFSGLKVAGRKLRAPEKTFATMDHNTSTKSASLDALSPMARIQVETLQDNCKEFGVRLYDIHHKNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVMATQTLRQNKAKTMKIEVRGHVAAGITAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMVAPDGITAEYLKGREFAPKGESWEQAIAAWAELKTDEDAIFDASVVLEASDIAPQLTWGTNPGQVVAIDGLVPNPEDESNATVKASIEKALEYVALSAGTCMTDVSINKVFIGSCTNSRIEDLRDAALHAKGRKVAAGVTAIVVPGSGLVKEQAEAEGLDKIFLEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRKAY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: F183B_MOUSE
Sequence: MAGRVGQMKNQDEVHQNQILRELFLKELRAQKLYTQYHVNPLRKVHTITRKPMSWHDNLEEPEDAKFLNLIHHAAQGPKKKYSETQTEAQEIGWDPNPLINPDRQDHRLNHFRVYHDITLYKAKLWSLGEDDHQK
What are the official names of this protein?
Protein FAM183B.
What is the protein family that this protein belongs to?
Belongs to the CFAP144 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium basal body.
Protein: MBR1_YEAS8
Sequence: MRMEKTTDKPLSAGDMNDEYSRGPIDDIDCLNFFERAVQDPCCEACDTEDADEELRAKLSSFNFQPDSSPCNAKCQQTLNPLCKIDEALPAESELAPSRNGSVSEANSDTNSIASTVHDPVDSKYGGMPSLRKAKTTSYFTSSSSNNTTMRNPLKKCNTNINGLLVNGRSSSSSRQSIPELFSGACTKKKNNVLLKSETPNSEFSSNSLQHCNSRSFSLPRSRSRSSAIAIPTHLYGLEKYVSPELDTLTADPEESIERFSNNRPREISSCCPNDTGDTSSSLSHSNTSSSLNFPLGTNTNQFHQPRQPVQQQQSSKPNFGAGRKKSFIEMSLASSFAG
What is the function of this protein?
Participates in mitochondrial biogenesis and stress response.
What are the official names of this protein?
Mitochondrial biogenesis regulation protein 1.
What is the protein family that this protein belongs to?
Belongs to the ISF1/MBR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RBM19_MOUSE
Sequence: MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQAALNHFHRSFIDTTRITVEFCKSFGDPSKPRAWSKHAQKSSQPKQPSQDSVPSDTKKDKKKKGPSDLEKLKEDAKFQEFLSIHQKRTQVATWANDALEAKLPKAKTKASSDYLNFDSDSNSDSGQESEEEPAREDPEEEQGLQPKAAVQKELSDMDYLKSKMVRAEVSSEDEDEEDSEDEAVNCEEGSEEEEEEGSPASPAKQGGVSRGAVPGVLRPQEAAGKVEKPVSQKEPTTPYTVKLRGAPFNVTEKNVIEFLAPLKPVAIRIVRNAHGNKTGYVFVDLSSEEEVKKALKCNRDYMGGRYIEVFREKQAPTARGPPKSTTPWQGRTLGENEEEEDLADSGRLFVRNLSYTSSEEDLEKLFSAYGPLSELHYPIDSLTKKPKGFAFVTFMFPEHAVKAYAEVDGQVFQGRMLHVLPSTIKKEASQEANAPGSSYKKKKEAMDKANSSSSHNWNTLFMGPNAVADAIAQKYNATKSQVFDHETRGSVAVRVALGETQLVQEVRSFLIDNGVCLDSFSQAAAERSKTVILAKNLPAGTLAAEIQETFSRFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLYLEWAPIGVFGAAPQKKDSQHEQPAEKAEVEQETVLDPEGEKASVEGAEASTGKMEEEEEEEEEEEEESIPGCTLFIKNLNFSTTEETLKGVFSKVGAIKSCTISKKKNKAGVLLSMGFGFVEYKKPEQAQKALKQLQGHTVDGHKLEVRISERATKPALTSTRKKQVPKKQTTSKILVRNIPFQANQREIRELFSTFGELKTVRLPKKMTGTGAHRGFGFVDFITKQDAKKAFNALCHSTHLYGRRLVLEWADSEVTVQTLRRKTARHFQEPPKKKRSAVLDGILEQLEDEDNSDGEQALQL
What is the function of this protein?
Plays a role in embryo pre-implantation development.
What are the official names of this protein?
Probable RNA-binding protein 19, RNA-binding motif protein 19.
What is the protein family that this protein belongs to?
Belongs to the RRM MRD1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Cytoplasm. Chromosome. Note=Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome periphery. By telophase localizes to nucleolar precursor body (NPB) (By similarity). In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the NPB. During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development.
Protein: SLAP1_BACHU
Sequence: SATVELYSNLAAKGLAVEFTSTSLKAALLNILSVDGVPATTAK
What is the function of this protein?
The S-layer is a paracrystalline mono-layered assembly of proteins which coat the surface of bacteria.
What are the official names of this protein?
S-layer protein 1, 102 KDa parasporal endotoxin.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer.
Protein: HLDD_ECOLU
Sequence: MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
What is the function of this protein?
Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
What are the official names of this protein?
ADP-L-glycero-D-manno-heptose-6-epimerase, ADP-L-glycero-beta-D-manno-heptose-6-epimerase, ADP-glyceromanno-heptose 6-epimerase, ADP-hep 6-epimerase, AGME.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
Protein: G3P_METBR
Sequence: MKSVGINGYGTIGKRVADAVSAQDDMKIVGVTKRSPDFEARMAVENGYDLYISVPERESSFEEAGIKVTGTADELLEKLDIVVDCTPEGIGAKNKEGTYEKMGLKAIFQGGEKHDQIGLSFNSFSNYNDVIGKDYARVVSCNTTGLCRTLNPINDLCGIKKVRAVMVRRGADPGQVKKGPINAIVPNPPTVPSHHGPDVQTVMYDLNITTMALLVPTTLMHQHNLMVELESSVSVDDIKEKLNETPRVLLLKAGEGLTSTAGFMEYAKDLGRSRNDLFEIGVWEESLNIVDGELYYMQAIHQESDVVPENVDAIRAMLEMENDPSKSIQKTNKAMGIL
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.