PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_CLOK5
Sequence: MDKLKVGLISLGCDKNRVDSEIILGNVKSAYEIVTDPKLADFIIINTCGFIESAKQESIDTILEMSQYKGKYNCRGIVVTGCLAQRYGIELMELLPEIDIMLGVNDYDKLVENINNFISDKQNKIHNCGYSDLNINEGKRILTTKSHTAYLRIAEGCDNYCTYCIIPKIRGKYRSRSIENILQECNELSLRGVKEVILIAQDTTRYGIDLYNKKMLPELMRSISKIEGIEWIRLLYCYPEEITEDIIDEIALNDKVCNYIDIPLQHISDNILKLMGRRGRKKDILRNINELRKKINDISIRTTIIVGFPGESEEDFKELKNFIENIKFDNLGVFKYSREEGTRAYKMKDQVSEELKTAREGELMMLQKHIIYSMQKYKIGNKYKVLVEGKKEGVWYGRNYAMAPDIDGVIYIKSKKELKVGTMIDVKITNSVEYDLVGVVYDESGK
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_SHEB5
Sequence: MKFELDTTDGRARRGRLIFDRGTVETPAFMPVGTYGTVKGMTPEEVRATGADILLGNTFHLWLRPGEEIMRKHGDLHDFMNWQRPILTDSGGFQVFSLGDIRKITEEGVHFRSPINGEKIFLDPEKSMQIQDALGSDVVMIFDECTPYPATEDEARKSMQMSLRWARRSRDEFDRLENPNSLFGIIQGGVYEDLRDESLKGLVDIGFDGYAVGGLAVGEPKADMHRILEHICPQIPADKPRYLMGVGKPEDLVEGVRRGVDMFDCVMPTRNARNGHLFTSEGVIKIRNARHRDDTSPLDTKCDCYTCKNYSRAYLYHLDRCNEILGARLNTIHNLRYYQMLMEGLRGAIETGTLDAFVADFYTSQGREVPELVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: RS12_NAUPA
Sequence: MPTINQLVRKGRKQVIKKSKSPALVSCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTSGYEVISYIPGEGHNLQEHSIVLVRGGRVKDLPGVKYHIVRGALDTAGVKGRVHSRSKYGTKKADAGKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: TRMD_CHLTR
Sequence: MEIDILSLFPDYFASPLQATILGRAIKQGALSVRSRDIREFGLGKWKQVDDSPYNGEGMLLMAEPVVQAIRSIRRKKSKVIYLSPQGQLLSAKKSRELASCSHLVLLCGHYEGIDERALTAEVDEEISIGDYVLTNGCAAALVLVDALARFIPGVLGNQESAEYDSLENGLLEGPQYTRPRVFEGESVPEVLLCGDHQKIADWRKQVSLERTRERRPDLYLQYFYGNSACLSTQEDLPRIEVVSPKTFSVVLEVQDLRKAKKFYSRMFGKECWDGDKLFLLGKTSLYLQQTKETRGPTTVFIELETDHDFVRFLKRWEILGGELGEQGTGGFPLRQVFDLDGHIWVVSCVQK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNA_CHLSY
Sequence: MELRTVWWENDAVCLIDQRKLPHTMEVVRCTDLAAVAYAIRSMQVRGAPAIGCTAAYGMALVAQQSVALTPSALLTELVQAKATLDSQRPTAVNLAWATSRMLRRAEAVASEGVEAIKHALHAEAEAIFAEDLAMCHAIGEHGASLIPPRGHVLTHCNAGGLATAGYGTALAPIRTAFAQGRPVHVFVDETRPFLQGARLTAWELLQAGIPQTLITDNMAAFMMQRGQIDCVIVGADRIAANGDVANKIGTYGLAVLARYHNIPFYVAAPSSTIDLATASGADIPIEERDPAEVTHIAGVAIAPQGVRAAHPAFDVTPNELVTAIITERGIVRPPYLAALRQLESGR
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: GLMM_ACISJ
Sequence: MTRKYFGTDGIRGTVGQSPITPDFALRLAHAVGRVLRRTQERPTVLIGKDTRISGYMLESALESGFNSAGVDVVLLGPLPTPGVAYLTRAQRASLGVVISASHNPYPDNGIKFFSAQGTKLPDAWEEEVEAALEQPPVWADSASLGKTRRLDDAAGRYIEFCKSTFANDLTLRGLKIVVDAAHGAAYHIAPKVFHELGAEVMAIGCAPDGLNINHQVGATHPDALVRAVRANHADYGIALDGDADRVQMVDAAGRLFNGDELLYVMVAARLARDEHVPGVVGTLMTNMAVEEALQRRGVKFMRAKVGDRYVLEELQRQHWLLGGEGSGHLLALDRHTTGDGLISALQVLQACVRSGKTLAQLLADVPLFPQVLLNVRLNPGQDWKTNPVLADAIRDAEAELGAHGRVLVRASGTEPLLRVMVEAREAEQANRCAQRMADAARAG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: VG11_ALHV1
Sequence: MQQTSNSNRTMMSFRRFTTTKLQLSHWDFTIYDTYIKMTNIHHITTTSNDSCLPTCPPLAEILKDKIPGYAFYSSAWQCQTMWMRFLIFGDEDNCIKTQLMFIDRSAENINIRLQHASYQMAPAHSLVFYIFPIILLRLDGLYLRVLPDKHPGVMDASCSQTWSCLNTPMPVVRLQGGMLSWDDEDMPFMLGQKTKPFLSKAVKVHALADEVCKVNDVCMGDNYMKIHLDFHFALDKHLPVDICMSPTNNTVLSFKFNPFVKTPWEPTPAKVPIVYMGEPVLIPGSCSTIVEYCNRYYVAKGLRITAIIVSVETDDTEFETDVCEWASECTAKIMVSNKSLFPRTLAPGTHIANAHFLLAERHFFSRILSDKNLKKLSTCIKLPGGFWVNAAKLPKLCKTCLSERV
What are the official names of this protein?
Uncharacterized gene 11 protein.
Protein: NDOR1_CANGA
Sequence: MSSSKIAVLYGSETGNAQDFAAILSHKLNRLHFKHTFSSLADYKREDILRCRYLFIVCSTTGQGELPRNVYETVTGDQKNTLWTFLKKKKLPADFLNHIKTAFLGLGDSSYPKFNYALRIIHNRMVNQLGAKEIFDRMEADEQSMAGSNKGTGLGIESVYFEFEKRIITYLMDRFPTRKVGNEIIQREEIDKELYLEPITYLRIDDPHDQQSFSGGPTTFVGDKLIKTGTITLNKRITAKDHFQDVRQFTFESCDDIKYKPGDTVALYSYNTDQSVERMLECQPQWIPLADKPLSFTNGIPTHLLDGGVVQPLTLRNLLKYHCDFMSIPRSSFFLKIWTFATDVTRMERGEEQMKDQRQKLYEFATDEDMQELYDYCNRPRRSILEVMEDFLSIRLPLEYLLDFFPPIKPRLYSISSTANCNNIELTVAIVKYKTILRKIRTGVCTDFISKLKVGDKIRYKIQQNDLIKEEYRSNPFVMVGPGVGLAPLLSAVRSKVSPEMSLYFGCRFKDKDYLHGKELEDMANQGLIKFYPVFSRDRENSPDTKYVQDVLWKFGEEVTNLLVERKGIFFLCGASGKMPIQIRLTLLEMLKKWGGFKDDASAKEYLRSMEKEYRYIQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: TRPC_ECO57
Sequence: MMQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPSKGVICDDFDPARIAAIYKHYASAISVLTDEKYFQGSFDFLPIVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLKMGVLTEVSNEEELERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFADGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGAIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVLDKAKVLSLVAVQLHGNEDQLYIDTLREALPAHVAIWKALSVGETLPARELQHVDKYVLDNGQGGSGQRFDWSLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLRAY
What is the function of this protein?
Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway.  The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain (By similarity).
What are the official names of this protein?
Tryptophan biosynthesis protein TrpCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the TrpF family.
Protein: RL21_THET8
Sequence: MFAIVKTGGKQYRVEPGLKLRVEKLDAEPGATVELPVLLLGGEKTVVGTPVVEGASVVAEVLGHGRGKKILVSKFKAKVQYRRKKGHRQPYTELLIKEIRG
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20 (By similarity).  Found on the solvent side of the large subunit.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: CH60_STRP2
Sequence: MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFGSPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREGIKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYISEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYILITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGAGNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKLRIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQIAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVASLILTTEAVVANKPEPVAPAPAMDPSMMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y0026_MYCTU
Sequence: MAFDAAMSTHEDLLATIRYVRDRTGDPNAWQTGLTPTEVTAVVTSTTRSEQLDAILRKIRQRHSNLYYPAPPDREQGDAARAIADAEAALAHQNSATAQLDLQVVSAILNAHLKTVEGGESLHELQQEIEAAVRIRSDLDTPAGARDFQRFLIGKLKDIREVVATASLDAASKSALMAAWTSLYDASKGDRGDADDRGPASVGSGGAPARGAGQQPELPTRAEPDCLLDSLLLEDPGLLADDLQVPGGTSAAIPSASSTPSLPNLGGATMPGGGATPALVPGVSAPGGLPLSGLLRGVGDEPELTDFDERGQEVRDPADYEHSNEPDERRADDREGADEDAGLGKSESPPQAPTTVTLPNGETVTAASPQLAAAIKAAASGTPIADAFQQQGIAIPLPGTAVANPVDPARISAGDVGVFTATPLPLALAKLFWTARFNTSQPCEGQTF
What are the official names of this protein?
Uncharacterized protein Rv0026.
What is the protein family that this protein belongs to?
To M.tuberculosis Rv0025 and Rv0739.
Protein: SYFA_BACC0
Sequence: MEARLKELKQKALELIEEAKELKGLNDVRVAYLGKKGPITEVLRGMGKLSAEERPRMGALVNEVREAIQTRLDDKISNLEKAVIEAKLATETIDVTLPGRPVETGCHHPLTAVVEQIEDVFIGMGYEVAEGTEVEKDYYNFEALNLPKDHPARDMQDTFYITEETLLRTHTSSVQARTMENNKEKGPIKIICPGKVYRRDDDDATHSHQFMQIEGLVIDKNIRMSDLKGTLQVFVKKMFGEDREIRLRPSFFPFTEPSVEMDISCMMCHGKGCGTCKGTGWIEILGAGMVHPNVLEMAGYDSKEYQGFAFGMGAERIAMLKYGVDDIRHFYTNDVRFLQQFKRA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP20A_YEAST
Sequence: MMPAKLQLDVLRTLQSSARHGTQTLKNSNFLERFHKDRIVFCLPFFPALFFVPVQKVLQHLCLRFTQVAPYFIIQLFDLPSRHAENLAPLLASCRIQYTNCFSSSSNGQVPSIISLYLRVDLSPFYAKIFQISYRVPMIWLDVFQVFFVFLVISQHSLHS
What are the official names of this protein?
UPF0479 membrane protein YPR204C-A.
What is the protein family that this protein belongs to?
Belongs to the UPF0479 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HIS8_ALIF1
Sequence: MEKLARKQVQALTPYLSARRIGGSGDVWLNANESPFDNEYQFNFARLNRYSECQPPELINAYAAYAKVKPEQVLTSRGADEGIELLVRAFCEPNQDAILYCPPTYGMYSISAETIGVETKTVPLTSNWQLDLPAIEASLENVKVVFVCSPNNPTGNIVDRKDILSLLEMTKDRAIVVMDEAYIDFCMEKSTVDLLVDYPHLAILRTLSKAFALAGLRCGFTLANEELINVLLKVIAPYPVPVPVAEIATQALSEAGLARMKYQMLDLSANRAYLQAGLMVLPGVTVFEGWGNYLLVKFPDGDSVFKAAWDHGIILRNSPIENCVRISVGNREECEKTLGFIRNQLI
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: RDOA_SALTY
Sequence: MNDNAFTFQTLHPETIMDALFEQGIMVDSGLTPLNSYENRVYQFQDEDRRRFVVKFYRPERWSVDQIREEHQFALELVKDEVPVAAPLAFNGQTLLAHQGYHYAIFPSVGGRQFEADNIDQMEAVGRYLGRLHQTGRKRPFTFRPDIGLAEYLFEPRQVFEDAALIPSGQKAAFLKATDTLLSAVTECWRTDFATLRLHGDCHAGNILWRDGPLFVDLDDARNGPAIQDLWMLLNGDKAEQRMQLETIIEAYEEVSEFDTAEIGLIEPLRAMRLVYYLAWLIRRWGDPAFPKNFPWLTGEDYWQRQTTTFIEQTKILHEPPLQLTPMY
What is the function of this protein?
A protein kinase that (auto)phosphorylates on Ser and Thr residues, probably involved in the extracytoplasmic stress response (PubMed:12511488).  Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species (By similarity).
What are the official names of this protein?
Serine/threonine protein kinase RdoA, Serine/threonine-protein kinase SrkA, Stress response kinase A.
What is the protein family that this protein belongs to?
Belongs to the SrkA/RdoA protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_HYPNA
Sequence: MAAKHVVFGAEARERMLRGVDTLANAVKVTLGPKGRNVVIEKSFGAPRSTKDGVTVAKEIELEDKFENMGAQMLREVASKANDTAGDGTTTATVLAQAIVREGMKRVAAGMNPMDLKRGISKAVAEVVSDLAHHSKKVKTNEEIAQVGTISANGETEIGQMIAEAMAKVGNEGVITVEEAKALETELDVVEGMQFDRGYISPYFITNPDKMIVELEDVLILLHESKLSSLQPLLPILESVVQSQKPLLIIAEDVDGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLQDLAVLTGGQVISEDLGIKLENVGMEMLGKAKRVSIDKDNTTIVDGGGKKKEIEARVSQIRKQIDDTSSDYDREKLQERLAKLAGGVAVIKVGGATEVEVKERKDRVDDALNATRAAVEEGIVPGGGVALLRSSKNIDVVGLNDDEKAGIDIVRKALEAPIRQIAENAGVEGSVVVNTILNNKSRSYGFNAQTEEYGDLVAMGVIDPVKVVRSALQNAASIASLLITTEAGIAEAPKKESAGGGGMPGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_MYXXD
Sequence: MAERTLVTSALPYANGPLHIGHAVEYVQTDIYVRFLRSCGRDVVYFCADDTHGTPIELNAAKQGLKPEEFIARFHEEHQRDFHDLDVRFDYFHSTNSPENRQYAELIYGRLKEKGDIERRNIEQTYCENDRRFLPDRFIKGTCPNCKASDQYGDACEKCGKAYDPTDLIDARCALCGTPPVRKHSEHLFFKLSRHEDFLQDVLRKPGFIHPGLATQLQGFFEKGLSDWDISRDGPYFGFAIPGETDKYFYVWLDAPIGYIATTEKWAKETGKAKSALDYWSADADTRIIHFIGKDIVYFHALFWPAVLNVAGFHIPSEIKVHGHLMLNGEKMSKTRGTMVPVRDYLDQLDPSYLRYFYAANLGPGVEDLDLNLKDFRQRVNGELVNNVGNLANRALSLLAGPLEKRLAPGRAEGPGRELVEAALARVPEVRDAFDKLEYRSAIRVITEIASAANGFLQTAAPWAQVKKDAEVARADLSDAADVAYLLGALLAPVTPRLSEKLFAQLGAEPLTFQALEGAKYPLLDRSRPIGTPEPLLPRLEEERVNAIIKLPEGAAAPQAAEARPAKGAKTEKKPAEAPAATQAAAPSAGAAESPGEIEYDDFAKVVLKAGKVLAAEKVQKADKLLKLTVDVGEGSPRTIVSGIAEAFAPEALTGRNVVVVANLKPRKLKGIESRGMLLTAGPGGKELSLLDPGDVAPGSEVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPC70_YEAST
Sequence: MDNILKASNMEGTSTMTVTSRSSEDSSCISNHEQDTDTHKDGDTSGLENSKISKRKWMKEFFKLSKSPASKSSRSIGSMKSNQSLVSMKSSDDGNSYKNDYSSICGNSLPSAGLSRSNSVKELKLDSTGSQRSKNNVAMLARSSTTSQTTCSSSSSSSSYNSIKGNENDILLQNNNHFRHNKEIPQSKGSSNINTASIMSQYNVDTQATAIMSDMQKQYDSQQMTSPFVNEDLHFDPNGEVSHVIKAIFKEIGYKYDDFSDIPVFQLMQEMYQLVKKNSSARRTKITDYASKLKEKEAQLKSQNDKILKLETTNKAYKTKYKEVSLENKKIKEAFKELDNESYNHDEELLKKYKYTRETLDRVNREQQLIIDQNEFLKKSVNELQNEVNATNFKFSLFKEKYAKLADSITELNTSTKKREALGENLTFECNELKEICLKYKKNIENISNTNKNLQNSFKNERKKVLDLRNERNLLKKEILLIECHGSYSLLLVSNILTCYRFLLPSDTIIETESLIKELLNMNNSLSNHVSSSDEPPAEYSKRLELKCVEFEEKLLYFYQELVTKKIIDVIYKCFINYYKKSRQTDQKSNQNSSTPYKQSQRQVPHSIK
What is the function of this protein?
Involved in the pathway that organizes the shaping and sizing of the prospore membrane (PSM) during sporulation.  May provide a meiosis-specific scaffold for the assembly of other proteins on spindle pole bodies (SPBs), and may be a limiting component for SPB formation.
What are the official names of this protein?
Sporulation-specific protein 21, Meiotic plaque component protein 70.
What is the protein family that this protein belongs to?
Belongs to the MPC70 family.
What are the subcellular locations of this protein?
Prospore membrane. Cytoplasm, cytoskeleton, spindle pole. Note=Localizes to the ends of spindle microtubules in cells in meiosis.
Protein: CSPLG_SORBI
Sequence: MSKMAEQKAAAVDGLGGAGAADAAPAGEAAAARVRPVETLLRAAPLGLCVAAMTVMLRDQQSNEYGTVAYSDLGGFKYLVYANGLCAAYSLVSAFYTAVPRPATVSRSWVVFLLDQVFTYLILAAGAAAAELLYLAYNGDKEVTWSEACGVFGSFCRQARTSVAITFGTVLCFILLSLISSYRLFSAYEAPPSSALGSKGVEIAAYPR
What are the official names of this protein?
CASP-like protein 2A1, SbCASPL2A1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HSLO_ALIFM
Sequence: MANNTLHRYLFEDLSVRGELVQLDDAYQQIISSKEYPKPVQNLLGELLVATTLLTATLKFEGSITLQLQGDGPVSLAVINGDNNQKVRGVARFEGDIAEDATLHQLMGRGYLVITITPKDGERYQGVVALEGENLAQCFEGYFERSEQLKTRLWLRLGEYEGKPHAAGMLLQVMPDGTGSENDFEHLEQLTDTIKNEELFGLPAEDVLYRLYNQDKVQLFEPQDVEFFCGCSRERSGGAIVTIDRAEVDDIIKTEGKISLHCDYCGTSYDFDSIDVANLFEQATSGNDTVH
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRK1_LEIME
Sequence: MTSRYERQEKIGEGTYGVVYKARDTSTAATVALKRIRLDSEEEGVPCTAIREISLLKELRHENIVKLLDVCHSEHRLTIVFEYLDLDLKKYLDRENGNLDAATIQHFMRDLLRGVAFCHQRSVLHRDLKPQNLLISREKELKLGDFGLGRSFAIPVRKFTNEVVTLWYRPPDVLLGSMQYGPPVDVWSVGCIFSEMATGTPLFAGKNDADQLMRIFRFLGTPNNRVWPSMNQYPNSNNMLSQPEFLQNFEPEWSNVLGSVPGYEKLGCAGVDLLERLLRYEPSERITAADALNHPYFSLQF
What is the function of this protein?
May be involved in some stage-specific role in the promastigote cell cycle.
What are the official names of this protein?
Cell division protein kinase 2 homolog CRK1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Protein: PLSX_JANSC
Sequence: MSDGAALTEDAVGDTVLSIDAMGGDLGPASVVSGLAKASAKNPTLRFIVHGDKPELERLIAKKRGLADVCELRHTKDVVTMDAKPSHVMRNGKDTSMWSTIEAVRDGDASVAVSCGNTGALMAISMIRLRKLEGVNRPAIACLWPSRNPSGFNVMLDVGADIRADAEDLLQYALMGASYARNGLDLSRPRIGLLNVGTEEHKGRAELKVAAELIDRAAPAADFEFVGFVEGSDLPSDRVDVIVTDGFTGNVALKTGEGTARLIRELLEQAFKKTPFSRVAALLAFTSLRRLSKRIDPRRVNGGVFLGLNGTVVKSHGSADPTGVAAAINLAAQLSATGFHKRLAARIAQAEAAASVAIQKEGSSE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: TSAD_PSESM
Sequence: MLVLGLETSCDETGVALYDSERGLLADALFSQIDLHRAYGGVVPELASRDHVKRMLPLIRQTLAEADCVATDIDAIAYTAGPGLVGALLVGASCAQALAFAWDIPALGVHHMEGHLLAPMLEENPPQFPFVALLVSGGHTQLVRVDGIGQYELLGETLDDAAGEAFDKTAKMMGMQYPGGPEISKAALQGVPGRFVFPRPMTDRPGLAFSFSGLKTSALNTWQQCQSAGDDSEQTRCDIALAFQQAVVETLTIKCKRALKQTGLKSLVIAGGVSANKALRVSLESMLGELRGHVYYARPEFCTDNGAMIAFAGCQRLQAGQKEDLSISVQARWPMEQLSGL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_ACET2
Sequence: MKDILILGIETSCDETSASVVKNGRQVLSNVISSQVALHQKYGGVVPEIASRKHVELIMPVIHQSLEEAGIKIEQVDAIGVTYGPGLVGALLVGLSAAKALAFALDKPLIGVHHIEGHIAANYIEHSLLEPPFVCLVASGGHSHIVYVQDYDKFEIMGKTRDDAAGEAFDKVARAVGLGYPGGPIIDKTAKLGNSKAIDFPRVHFGDQSLDFSFSGLKTAVLNYINSMEQKGEKYSVEDVCASFQAAVVDVLTDNLISAARIKGVKKVALAGGVAANSLLRSELVEKAKGLGLEVFYPKPVLCTDNAAMIACAAYYEFLRGHTSDVYLNAIPGLKLGER
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS3_METTP
Sequence: MAVEKKFVQEGFTKALVDEYLAKELDRAGYGGMVMNRTPMGTQITVYAEKPGMVIGKGGKLIRKLTRDLERRFRLDNPQIDVQDVGKSDLNARVVANRLASSLEHGWYFRKAGQSMLRRVMDSGALGCEIVISGKLTGPRSRVEKFLAGYIKHSGKPAEEIVDTGYAVAVKKLGAIGCQVRIVPPGAVLPDDFQINAPPKEPEKEPVVEEAVLEAEPSQAAETQEQQAGEKKSELDRLLDEPVETPPTTEEGQSPQEPESRTEMSEAETHGDIQDR
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: EF107_ARATH
Sequence: METFEESSDLDVIQKHLFEDLMIPDGFIEDFVFDDTAFVSGLWSLEPFNPVPKLEPSSPVLDPDSYVQEILQMEAESSSSSSTTTSPEVETVSNRKKTKRFEETRHYRGVRRRPWGKFAAEIRDPAKKGSRIWLGTFESDIDAARAYDYAAFKLRGRKAVLNFPLDAGKYDAPVNSCRKRRRTDVPQPQGTTTSTSSSSSN
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF107.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.