PharMolix/UniProtQA huggingface dataset:
Protein: TRAIP_XENLA
Sequence: MPIRAYCTICSDFFDNARDVAAITCGHTFHQECLLQWFHSAPHRTCPQCRIQVSSRQIINKLFFDIGGEEETVLDAESLKNEVDRIKASLLVKEKEKRECQGLVDSLREMLDVRNVTIQSQQKELGDMEMLCSTLKKQIKFLDKQQSETKAAKDEARKLRNKLKTMESIEVLLQSQRSEVEEMIRDMGSGQAAVEQLAIYCVSLKKEYENLKEVRKSSAEMTEKLRKELFSSNHKAQKAELELTKVREELSASQKELHSADKEIMSLKKKVEFLQKTLTTPTASNEAISRLIFESPAPIGLERPKLRPPMMGNDINLDVTFDIDTPEHNTQKSVVAPFKKMKFDNKEHPLSSPTKNPLQESKGLMSWAGGRTGADEDDDLTLPSFIKNSLLHKKPVGSLLGLRQNTGAVRTGFDGLGGRTKFIQPSNLTEIRPLHQKMKRKKVSRPTACTSSLANQPRLEDFLK
What is the function of this protein?
E3 ubiquitin ligase required to protect genome stability in response to replication stress (PubMed:30979826, PubMed:30849395, PubMed:30842657).  Acts as a key regulator of interstrand cross-link repair, which takes place when both strands of duplex DNA are covalently tethered together, thereby blocking replication and transcription (PubMed:30979826, PubMed:30849395, PubMed:30842657).  Controls the choice between the two pathways of replication-coupled interstrand-cross-link repair by mediating ubiquitination of mcm7 subunit of the CMG helicase complex (PubMed:30842657).  Short ubiquitin chains on mcm7 promote recruitment of DNA glycosylase neil3 (PubMed:30842657).  If the interstrand cross-link cannot be cleaved by neil3, the ubiquitin chains continue to grow on mcm7, promoting the unloading of the CMG helicase complex by the vcp/p97 ATPase, enabling the Fanconi anemia DNA repair pathway (PubMed:30979826, PubMed:30842657).  Only catalyzes ubiquitination of mcm7 when forks converge (PubMed:30842657).  Also involved in the repair of covalent DNA-protein cross-links (DPCs) during DNA synthesis: promotes ubiquitination of DPCs, leading to their degradation by the proteasome (PubMed:30595436).  Also acts as a negative regulator of innate immune signaling by inhibiting activation of NF-kappa-B mediated by TNF (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase TRAIP, TRAF-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the TRAIP family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus. Chromosome. Cytoplasm. Note=Localizes to DNA damage sites in response to replication stress.
Protein: RL18_HYDS0
Sequence: MKLTREEKRIKRHRRIRKKISGTASRPRLCMYRSLNAFYASLVDDITGNAILTVSSLGKEYVDATGKRGGKSIEAVQKVAEILVQKAKEKGIDKAVFDRSGYLYHGKVKAFAEKCRELGLIN
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: LKHA4_XENLA
Sequence: MADPSSFASPEKFNIKHMHLKLHVDFTSRAIAASTSLTVRSLQDSLASLILDTKDLTIKKVAVNGKDATFALGTTHSFKGTPLEITLPFSLTRGQEVIVEIDSVTSPKSSALQWLNKEQTAGKIHPYLFSQCQATHCRSIIPCQDTPSVKFTYYSQVSVPKELMALMSALRDGELSEQSDSNRKIYRFKQNVPIPSYLIALVVGALEGRKVGPRTTIWTEKELLEPSVYEFAETEKMLKYAEDLAGPYVWGQYDLLILPPSFPYGGMENPCLTFVTPTVLAGDRSLASVIAHEISHSWTGNLVTNETWENFWLNEGHTVYLERRIDGRLYGEEFRQFKALGGWKELQNSVNTFGATNPLTNLVPNLHEVDVDAAFSSVPYEKGFALLFYLEQLLGGPEIFLGFLKSYIQMFAFKSVTTEEWKKFLYSYFKDKVDILDKVDWKGWMHTPGMPPVQPKYDMTLANACITLGQKWVKATESDLGSFSADDVKDLSSHQLIEVLAILLLEKPLPVSHVKRMQEVYNLNDVKNSEIRFRWLRLCIRAGWEDVIPLALAMATEQGRMKFTRPLYRDLYNFEKAREQTVNTFLKNRSFMHPVTEMLVAKDLHISAS
What is the function of this protein?
Bifunctional zinc metalloenzyme that comprises both epoxide hydrolase (EH) and aminopeptidase activities (PubMed:8706657, PubMed:9744798, PubMed:24333438).  Acts as an epoxide hydrolase to catalyze the conversion of leukotriene A4 (LTA4) to the pro-inflammatory mediator leukotriene B4 (LTB4) (PubMed:8706657, PubMed:9744798, PubMed:24333438).  During the conversion of LTA4 to LTB4, a second product is formed, the isomeric delta6-trans-delta8-cis-LTB4 (5S,12R-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid), with a relative formation of 10% delta6-trans-delta8-cis-LTB4 compared to 90% LTB4 (PubMed:8706657, PubMed:9744798).  The production of delta6-trans-delta8-cis-LTB4 seems to dependend on the phenylalanine residue at position 375 (PubMed:8706657, PubMed:9744798).  Has also aminopeptidase activity (PubMed:24333438).
What are the official names of this protein?
Leukotriene A-4 hydrolase, LTA-4 hydrolase, Leukotriene A(4) hydrolase, Tripeptide aminopeptidase LTA4H.
What is the protein family that this protein belongs to?
Belongs to the peptidase M1 family.
Protein: OATA_STAAR
Sequence: MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKSQFARTVLVILLLIPSIIVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK
What is the function of this protein?
Responsible for O-acetylation at the C(6)-hydroxyl group of N-acetylmuramyl residues, forming the corresponding N,6-O-diacetylmuramic acid of the peptidoglycan.  O-acetylation of the peptidoglycan is the major determinant for lysozyme resistance.
What are the official names of this protein?
O-acetyltransferase OatA.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HXC8A_DANRE
Sequence: MSSYFVNPLFSKYKGGETLEPTYYDCRFPQSVARSHTLVYGHGAAAPGFQHPSHHVQDFFHHGTTGISNPGYQQNPCALACHGDATKFYGYEALPRQPLYGTQQEATLAQYPDCKSSNSTNPGEGQGHLSQNSSPSLMFPWMRPHAPGRRNGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALSLTERQVKIWFQNRRMKWKKENNKDKFPGQRGEAEAEAEEEGNEDGEAEEGEDKETEEKEESKE
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-C8a.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PTPA2_ASHGO
Sequence: MSDGAELKMAAQKRLLTGSDLDKWKASKTFEELLRFVSSLAQSVRGRENSEHAEPVSPAIEALEALLEEMQGIAAHHPVLQDAATSRFGKVEFRDFHKEVQARAEALVLQVDPSLTDEQAQELAVYLGNAWGDCKRIDYGSGHELNFVCFLYGLWKYGVLSEHDFTNAVLRVFVKYMDVMRVLETKYWLEPAGSHGVWGLDDYHFLPFLFGAFQLATHKHLKPKSIHNPEVVELFENRYLYFGCIAFINRVKTTASLRWHSPMLDDISGVRSWTKVSEGMVKMYKAEVLGKLPIMQHFFFSRFLPVPDGVSPPRTSEEELADCSEHAHSTWGDCCGIPIPSAVAASEATRKHSKPLPFD
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.  Acts as a regulatory subunit for PP2A-like phosphatases modulating their activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a direct target of the PPIase.  Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2Ai) in presence of ATP and Mg(2+) by dissociating the inactive form from the complex (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 2A activator 2, Peptidyl-prolyl cis-trans isomerase PTPA-2, PPIase PTPA-2, Rotamase PTPA-2, Phosphotyrosyl phosphatase activator 2.
What is the protein family that this protein belongs to?
Belongs to the PTPA-type PPIase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: G20U_BACSU
Sequence: MSEQLIQAVNKQVANWTVMYVKLHNYHWYVKGKDFFTLHEKFEELYNETATYIDDLAERLLALNGKPIATMKESLETASVKEAAGNETAEQMVQSVYDDFTVIAEELKNGMDLADEVGDETTGDMLLAIHQNIEKHNWMLKAYLG
What are the official names of this protein?
General stress protein 20U, GSP20U, DPS protein homolog.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
Protein: IF2_CUPTR
Sequence: MASTTVAQLAAELSRSAAALLEQLQAAGVGKATPEDIITESDKTRLLDYLKRSHGQADDSARKKITLTKRETSEIRQSDATGKTRTVQVEVRKKRVLIKRDDAAPEHQADGAEAQAHVVDAAEEARREEEERRQAEQLARQEAEAKAAREAAEREEAERRARQEALEAEQRRQAELAARKAEEEAAASRAVTEANEDTSRKKAEDEKARVAAERAEAQKAADEAKAAADKARAEQEIAARKRREAAEAEARAIQQMLNAPARVLKAPSERKAEEKKAEQTGTLHKPVKPAGTEAKPGEKKPVTATATTTTDKKGKVVKAGTSSTWQDEGSRKKGSGLKTRGDSSGGVGGWRGGPRGRGGRQQQHDDSRSNFQAPTEPVVREVHVPETISVADLAHKMAVKASEVIKQMMKLGQMVTINQVLDQETAMIVVEEMGHKAYAAKLDDPEALLVVDGEEHEDAELLPRPPVVTVMGHVDHGKTSLLDYIRRTKVAAGEAGGITQHIGAYHVETDRGVITFLDTPGHEAFTAMRARGAKATDIVILVVAADDGVMPQTKEAIAHAKAAGVPIVVAINKVDKPEANPDRVKQELVAEQVVPEEYGGDSPFVPVSAKTGAGIEDLLEQVSLQAEVLELKAPVDAPAKGLVVEAQLDKGKGPIATILVSSGTLKRGDVVLAGSAYGRVRAMLDENGKATKEAGPSIPVEIQGLSEVPAAGEEVLVLPDERKAREIALFRQGKFRDVKLAKQQAAKLENMLEQMTEGEVQTLPLIVKADVQGSQEALVQSLQKLSTAEVRVQIVHGGVGGISESDVNLATASKAVIIGFNVRADAGARKLAEHNGIDIRYYNIIYDAVDEIKAAMSGMLAPEKRETTTGTVEVRQVFRVPKVGAVAGCMVTDGVVKRNSLVRVLRNNVVIHDGELDSLKRFKDDVKEVKQGFECGLSIKNFNDVQEGDQLEVYEITEVARTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETI_ECOL6
Sequence: MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAERRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAALIDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: EFUG_HORCR
Sequence: MEFLEYLTPITSHQWGIGSVFLLISIPLIVTRLLTTFWSWRELSAANQKAPGQKRGPTRPTTIPLIGHIVSFLLDGPGFLYNTARYYGRGIPVRVHLATFPSYVISGPELVSAFLKDSTRSLTPMKRSLNYMEHAFGCPHDLVKSFATSDDKDMEQQIHSALQNMLSGPRLGILSERYQQSVKSQVLSVDAGIGDEWVELPDLCTFVETHVFQAATRTIFGPSIVDLNPTLAKDFWNFNKRVKTMFLGIPAWANRTAIRARDDMTEDIKRWQRHAEKNCNIDEIPEDVEWEEYYGSKSTRIRQQLLTKRGITNESARAAENLSMMWATNANSIPAACWFLLQTLHDPLLQARVRKELDAVRIHDTEETNKAAAFKFDITGLTESPLCQSVYAEVLRLGVAAMIVREPTHDNLALGDWKFKKDEFISVPTNNELMDPDFWNSGTPKDPHPLDKFWADRFLVHPDDPQSGPRKDAKKQKAKSDGKPYFSMDGCTWNWIPYGGGAHLCPGRNFAKREIMLTSAIMLTAFDIELLTDTLPKHDKSLFGFGTLPPIGKAPCRIRRRQL
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of enfumafungin, a glycosylated fernene-type triterpenoid with potent antifungal activity, mediated by its interaction with beta-1,3-glucan synthase and the fungal cell wall (PubMed:30051576).  The pathway begins with the terpene cyclase-glycosyl transferase fusion protein that most likely uses 2,3-oxidosqualene as substrate and catalyzes glycosylation immediately after cyclization (Probable).  The fernene glycoside then could be processed by the desaturase efuI which catalyzes isomerization of a double bond established by efuA to form the core structure (Probable).  The latter would then undergo a series of hydroxylations in unknown order at C-2, C-19, C-23 and C-25, which would be catalyzed by two of the three cytochrome P450 monooxygenases efuB, efuG or efuH (Probable).  The hydroxy-group at C-25 becomes oxidized by the dehydrogenase efuE to enable a spontaneous, non-enzymatic hemiacetal formation with C-23 (Probable).  After hydroxylation at C-2, acetylation by the acetyltransferase efuC takes place (Probable).  The final steps in enfumafungin biosynthesis require expansion of the 5-membered ring by lactonization via a Baeyer-Villiger reaction mediated by one of the BGC's cytochrome P450 monooxygenases (efuB, efuG or efuH) followed by ring cleavage (Probable).  This type of reaction would establish a double bond between C-20 and C-21 which could be reduced by the reductase efuL to form the final product (Probable).
What are the official names of this protein?
Cytochrome P450 monooxygenase efuG, Enfumafungin biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NU4LM_EULCO
Sequence: MPSISTNIILAFITALLGMLIFRSHLMSSLLCLEGMMLSMFILSTLTILNLYFTTSFMMPILLLVFAACEAAVGLALLVTVSNTYGLDYIQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ABIL5_ORYSJ
Sequence: MEVAEAGVDGVAGRRQQEEASGAAPFGRSSSLIGAAGFDGALRELKDLRSQLHQTADCCEKAFLDTEKKKLILESTKGYICDAIVAVIDHLGTVSSKLEQQLQEKIEITQTEKKLNFLKQRLLTCEQYAITLKLLTVRGDNDAIQYHRRYLSQSTGGTKEENGANSRKDDVKFVEYNSPTIPGAILTFKPYDIQSTIGRERSVATTDSESPTTDAKSSFSFRAEDVPIVLAEHRKKANHGSNILSFIRKGRRHA
What is the function of this protein?
Involved in regulation of actin and microtubule organization.  Part of a WAVE complex that activates the Arp2/3 complex (By similarity).
What are the official names of this protein?
Probable protein ABIL5, Abl interactor-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the ABI family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL22_MYCPN
Sequence: MIAFAKQFRVRISPQKARLVCQLIVGKKTADAQNILSNTPKKAATLIAKLLNSAIANATNNHGMNGDALYVFECVANQGPSMKRTIPRAKGSSNMITKRSSNLVVKLSDNPNERQELIKQQKALVKKRVEGQQKAKMARQKAVTSVVKAPSKTQGGVQK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ATG13_ASPOR
Sequence: MHQHPRSPAPTAPTSSARPNSSRSRELDYRPNSPAADVRVHNSRGLGIETEPDSSGQTVQPAKEAIAKLNQIISNYHTKAALIILHSRIELPPSFNKGSDTPRVNRWFNVEIEDTDVLREQLRTWRTCDATENRPPPLIIETYLDTKGLTNNQTLVALDENGKRWDVLEALAASQQAHPVRPPSASSDDVILERWRVELGDTSNALPADLGSILPTVYKKSIVLFRSLFTYSKFLPAWKFAKRNGRLRANPALRIKYRIIIGSPNQVSSKPDHLTMPLYESSSKVVETYSFGVTDSPAGPFSAQVTYRTSCDFRVDDSEALLSSRFMGADDEIFRPSLPTRVVDSKVPPPEIGSLPQERRTIEDPDPGRAYGSLSTFHQVGPTTSASPISALRAKGKLGTSSPSSPGSSSRKALAVAKASPVGRAAALASEGSPGVVRRPSISFQPFKAPPLSASPSLVDPPLSSPRSVSGPRPHPPMAASARKSFPAVQDNSIASPSSASPRPSSISRYSSAFSHRRGRPSSGGINKLEDDTSSGKASATSSAQPGSGLLAEPTGTSADSIHADDENISEFLKMLDLRKDLLNTSGSAALDATARRTTVTSAALTRFQRMRDSNAALSDSMSSSLLLQRSSNSSSKQLSGVPPMVAGTSISTASSPGKPISPHTPHTPAIPSRLSSNSIVDYTHSEGNGTELSQGHGSPLDENTSDGTTMEHGPSAVNAIDIPTSPRLFPPVYRRSSSAAHRPRTVAVDDDEIFPFNRSVSLGAEERSNLSLGALHRQHEYESSDTATHRAQREPRPMSSNEDAVVPPSSITRGQGSHKGVTPGPTVASSSSSHHHVYQPRFSHSRGRGSSGGHHSLSSGSSSLARGAAITPGLAERESERDGNGSGSNSVTSAMEDRRGVGRRPSAGRGGPPQSAQLEEDEPLLFAMSDFGASRRSFEEGKHVNHAHDPTGNIAGSRRGGSSRRGGGFHAWS
What is the function of this protein?
Activates the atg1 kinase in a nutritional condition dependent manner through the TOR pathway, leading to autophagy.  Also involved in cytoplasm to vacuole transport (Cvt) and more specifically in Cvt vesicle formation.  Seems to play a role in the switching machinery regulating the conversion between the Cvt pathway and autophagy.  Finally, atg13 is also required for glycogen storage during stationary phase (By similarity).
What are the official names of this protein?
Autophagy-related protein 13.
What is the protein family that this protein belongs to?
Belongs to the ATG13 family. Fungi subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: RL21_FUSNN
Sequence: MYAVIKTGGKQYKVTEGDVLKVEKLNAEVNTTVELTEVLLVAGGDNAVKVGKPLVEGAKVVVEVLSQGKGPKVINFKYKPKKASHRKRGHRQLFTEVKVTSIIA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: Y4LO_SINFN
Sequence: MQLSRRAEIGNPSSRNLSPRINEKVELLGQALEHARRAGMSSSLMEYGRQVARHLSANVQPDEKILSLDIRNLPLLAASYNRRYPDLDLRHMDSPARFFDALNDRSSDGAWRAVVRLADGEQHHVAADVRTRAGAAPTIIVMEGANFYTFVASYFKLRGDSFRQLGTQAKWAFIEVGAQKSAADCVMFGVQFALAAYRELPTFDAWHDNLHHHGTIAHEGDYSSDYMPRRHAGICANKPFSWGEVPPSDLLQALSLQQCN
What is the function of this protein?
Serine/threonine-protein acetyltransferase translocated into infected cells, which mediates acetylation of serine and threonine residues of host target proteins.
What are the official names of this protein?
Serine/threonine-protein acetyltransferase NGR_a02610.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase YopJ family.
Protein: RS19_PHYS2
Sequence: KLGEFSPTRTYRGHNKKDKKMQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MAO1_SALG2
Sequence: METITKKARSLYIPYAGPVLLEFPLLNKGSAFSAEERRNFNLSGLLPEVVESIEEQAERAWLQYQGFKTEIDKHIYLRNIQDTNETLFYRLVQNHLEEMMPVIYTPTVGAACERFSEIYRRARGVFISYPNRHNMDDILQNVPNHNIKVIVVTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRHPRITDDEYYAFVDEFIQAVKQRWPDILLQFEDFAQKNAMPLLTRYRDEICSFNDDIQGTAAVTVGTLIAASRAAGSQLSEQKIVFLGAGSAGCGIAEQIIAQTQREGLSEDAARQNVFMVDRFGLLTDRMPNLLPFQAKLVQKCDNLQHWDTENDVLSLLDVVRNVKPDILIGVSGQTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFSPVIWKDKIYPIAQCNNAYIFPGIGLGVIASGASRITDEMLMSASETLAKHSPLVNNGEGLVLPALKDIQVVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWKPEYRDYRRTSI
What are the official names of this protein?
NAD-dependent malic enzyme, NAD-ME.
What is the protein family that this protein belongs to?
Belongs to the malic enzymes family.
Protein: RS14Z_NAUPA
Sequence: MAKKSMIAKAKRKPKFKVRAYTRCSICGRVHSVYRDFGICRICLRKMANEGLLPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: RPOZ_FRAAA
Sequence: MAGTVAHPEGITNPPIDELLEATDSKYSLVIYAAKRARQINAYYSQLGEGLLEYVGPLVETTNAQEKPLSIALREINAGLLTHETVSDSLPPVA
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: PETN_ARAHI
Sequence: MDIVSLAWAGLMVVFTFSLSLVVWGRSGL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: INSA7_ECOLI
Sequence: MASISIRCPSCSATEGVVRNGKSTAGHQRYLCSPCRKTWQLQFTYTASQPGKHQKIIDMAMNGVGCRASARIMGVGLNTVLRHLKNSGRSR
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 7 protein InsA, IS1f.
What is the protein family that this protein belongs to?
Belongs to the IS1 elements InsA family.
Protein: STKLL_ARATH
Sequence: MDKANTNRSKVCGGSGEAKLTGKKRKNVSAKQSKKDAKKENSQMLKWSSKDEVLVLQGMLDFKSVTGKNPVDDINGAYEFVVHEYISTVIDEDFIEKMKSLKKKLKKKQRIYDKDPSSSEPLYQKSSEWLKMIWGYDVESALEKPRKSKRIIKL
What are the official names of this protein?
Probable transcription factor At4g00232, Storekeeper-like protein At4g00232.
What is the protein family that this protein belongs to?
Belongs to the GeBP family.
Protein: MRAZ_SALTY
Sequence: MFRGATLVNLDSKGRLTVPTRYREQLIESATGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWYQQVKEDIDAEQSATETLSERLQDLSL
What is the function of this protein?
Negatively regulates its own expression and that of the subsequent genes in the proximal part of the division and cell wall (dcw) gene cluster.  Acts by binding directly to DNA.  May also regulate the expression of genes outside the dcw cluster.
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: BUT78_GIBZE
Sequence: MSWKAIAKAAQAEVLDAIPTKWKLDPAKYRTLTDVTSVPRECGILSDAQLSITDLTALEVVKRIESRELTAVQALEAFGARTAIAHQLVNCLMDWFYEDGLRQAEELDKSFKATGKLKGPLHGVPVALKDFHFVAGRPTTTGYVSRRDFRPEHDSALVKTLRDAGAVFYCKTTMPQSGMAIETVSNLWGRTLNPYNTALSAGGSSGGDAVLVALKGTPITPSTDLGGSIRVPAAFNGLYAIRPTSDRIPKGGMDNINSGQISIKLSCGPICHSMEDLESFTKLINAYPENQNDPTSVPVPWKTVKPIEGKLTIGLMKWDKVVMPHPPVIRALEHTKRTLEKAGHEVVEFDVPFDCWDAIQTTFDTYYQSGHSGTLSTLEATGEPLIPAFEDLIKVFGSKEISAAESQQLNVKARIFREKFRDAWDATTKLTSTGRPVDALICPTAPAVGYPHDFNVYWGYTSLFNLLDYPSVILPVANFKVNPQDDPVASNYKPLETNPYDKPNHELYKPELFSSQPSTIQVVGRPFQDEELIKVSSVMDDLLRAM
What is the function of this protein?
Amidase; part of the gene cluster that mediates the biosynthesis of butenolide, a mycotoxin that shows antibiotic activity but does not seem to play a major role in the spread of head blight in wheat (PubMed:17175185).  Butenolide is derived from glutamic acid via a 4-acetamido-2-butenoic acid intermediate (Probable).  The predicted function of the NADH:flavin oxidoreductase FG08077, the cytochrome P450 monooxygenase FG08079, the decarboxylase FG08083, and the putative acetyltransferase FG08082 are consistent with this pathway, however, the respective activities of the butelonide biosynthesis cluster enzymes have still to be experimentally determined (Probable).
What are the official names of this protein?
Amidase FG08078, Butenolide biosynthesis cluster protein FG08078.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: RSMC_PSET1
Sequence: MSVLTNPSLLLLRNSEKLVGKSILVVNFVQDGFLAELKKRNPESKITAFSYNHANGEFAKNTPGVDVCVNHCISGNDFDLVILYYPKSKPEVLMALDNIRAVITADAELLVVGENKSGVKSIEKQLTDKANFSNKIDSAKHCVLYSFAELKQLSQFNISDYHKPFTVSVADSEFTAISIPGVFNHGNLDVGTKILLENAPLIKQGTVLDFGCGAGLIATYLGLQNPALSFVCSDVSALAIYATTQTLKLNNIKGEALLSDGLTNITGKFDLIISNPPFHTGIATDYTVAETFLANAKQHLTKAGKLNIVANSFLKYPPILEAQFDNYQTVFKNNKFAVYSS
What is the function of this protein?
Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase C, 16S rRNA m2G1207 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase RsmC.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmC family.
What are the subcellular locations of this protein?
Cytoplasm.