PharMolix/UniProtQA huggingface dataset:
Protein: Y4837_ARATH
Sequence: MVERKKRKQIQRNNSESNRNQKRRISHDKINRDELVVYRILCPIDVVGGVIGKSGKVINAIRHNTKAKIKVFDQLHGCSQRVITIYCSVKEKQEEIGFTKSENEPLCCAQDALLKVYDAIVASDEENNTKTNVDRDDNKECRLLVPFSQSSSLIGKAGENIKRIRRRTRASVKVVSKDVSDPSHVCAMEYDNVVVISGEPESVKQALFAVSAIMYKINPRENIPLDSTSQDVPAASVIVPSDLSNSVYPQTGFYSNQDHILQQGAGVPSYFNALSVSDFQGYAETAANPVPVFASSLPVTHGFGGSSRSEELVFKVLCPLCNIMRVIGKGGSTIKRIREASGSCIEVNDSRTKCGDDECVIIVTATESPDDMKSMAVEAVLLLQEYINDEDAENVKMQLLVSSKVIGCVIGKSGSVINEIRKRTNANICISKGKKDDLVEVSGEVSSVRDALIQIVLRLREDVLGDKDSVATRKPPARTDNCSFLSGSSNAGYTLPSFMSSMASTSGFHGYGSFPAGDNVLGSTGPYSYGRLPSSSALEILIPAHAMSKVMGKGGGNLENIRRISGAMIEISASKTSHGDHIALLSGTLEQMRCAENLVQAFVMST
What are the official names of this protein?
KH domain-containing protein At4g18375.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNZ_PROM3
Sequence: MQVTFLGTSSGVPTRARNVSAVALRLPQRAELWLFDCGEGTQHQFLRSDLRLSQLRRVFVSHMHGDHVFGLPGLLASLGLSGNSNGVDLYGPDPLESYLQGVLRNSSTRIGYPLKVHRVRDAAEQNLIVFEDKDILVRCTPLTHRVPAYAYRVEQKPKPGHFNLERAQRLGIPPGPVYAALKRGEQVSLDDGRVVDGRDFCGPDRPGASIVFCTDTVFSEAAVALAAGADLLIHEATFAHSEAEMAYQKQHSTSTMAAQTAAEAGVGKLVLTHLSPRYAPGNPVTPNDLLREAQAIFSNTILAKDFLSFEVAPRCNSS
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: DAPAT_SYNSC
Sequence: MVQVNGNYLKLKAGYLFPEIGRRVKAFSSANPDAALIRLGIGDVTEPLPLACREAMKTAIDAMGTAEGFHGYGPEQGYGWLREAIAKNDFQARGCDISAEEIFVSDGSKCDSSNILDILGEGNKVAVTDPVYPVYVDSNVMAGRTGEAGEIGRYAGLTYLPISADNGFAALIPSEPVDLIYLCFPNNPTGAVATREQLQAWVNYARANGALILFDAAYEAFIQDPELPRSIFEIEGARDCAIEFRSFSKNAGFTGTRCAFTVVPKGLKGKAANGEAVELWGLWNRRQSTKFNGVSYIIQRGAEAVYSEAGQAEVKALVSFYMENAAIIRRELTAAGLTVYGGEHAPYVWIKTPEGMDSWGFFDHLLNKANVVGTPGSGFGAAGECYFRLSAFNSRANVDEAMARIKAL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: DOF22_ARATH
Sequence: MVFSSVSSFLDPPINWPQSANPNNHPHHHQLQENGSLVSGHHQVLSHHFPQNPNPNHHHVETAAATTVDPSSLNGQAAERARLAKNSQPPEGALKCPRCDSANTKFCYFNNYNLTQPRHFCKACRRYWTRGGALRNVPVGGGCRRNKKGKSGNSKSSSSSQNKQSTSMVNATSPTNTSNVQLQTNSQFPFLPTLQNLTQLGGIGLNLAAINGNNGGNGNTSSSFLNDLGFFHGGNTSGPVMGNNNENNLMTSLGSSSHFALFDRTMGLYNFPNEVNMGLSSIGATRVSQTAQVKMEDNHLGNISRPVSGLTSPGNQSNQYWTGQGLPGSSSNDHHHQHLM
What is the function of this protein?
Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence.
What are the official names of this protein?
Dof zinc finger protein DOF2.2, AtDOF2.2.
What are the subcellular locations of this protein?
Nucleus.
Protein: KBTBB_MOUSE
Sequence: MENSVAPFVLYSGTEPRTPGEDSLPLPAEEEGAASTAQTPCSLSASLCFSSGDDSPPQSRASAAEGSEASPPSLRSDLRVVETQWDVSSAASPESPEECARPEEPASPEDPPSRHEHARPVELESLDELGEPVPVPPGVGSVHGEPDLVIEVAGRRLRAHKAVLAARSDYFRARASRDVLRVQGVSFTALRLLLADAYSGRMAGVRPDNVAEVVAGARRLQLPGAAQRATEAMAPQLSLDNCYEVLSAGKRQRLTELRDAAYRFMSDHYLEVLREPAVFGRLSGAERDLLLRRRLCTGRACLLAAALGTTGERSGSRPQSPSGDAESRGDAAVYCYQAEAGEWRELTRLPEGAPARGCGLCVLFNYLFLAGGVAPAGPDGRARPSDQVYCYNPVTDSWSTVRPLRQARSQVQLLALDGHLYAVGGECLLSVERYDPRADRWTAVAPLPRGAFAVAHEAATCNGEIYVSGGSLFYRLLKYDPRRDEWQECPCSSSRERSADMVALDGFLYRFDLCGSRGEAQAAVGSGGGVSVFRYHCLAKQWSQCAVHLRPPGAPAGLQPFRCVALDGTIYCVSRAGTWRFVPSQDTEAGSDMGPGGSFEPEPLGSPLDVRGVLFPFVLNLPEKPDRGEQGAV
What are the official names of this protein?
Kelch repeat and BTB domain-containing protein 11.
Protein: THBG_RAT
Sequence: MSMFFYLFLLVLGLQATIHCAPHNSSEGKVTTCHLPQQNATLYKMPSINADFAFRLYRKLSVENPDLNIFFSPVSISAALAMLSFGSGSSTQTQILEVLGFNLTDTPVKELQQGFQHLICSLNFPNNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHEINSYVEKQTKGKIVGLIQDLKLNIIMILVNYIHFKAQWANPFRVSKTEESSNFSVDKSTTVQVPMMHQLEQYYHYVDVELNCTVLQMDYSANALALFVLPKEGHMEWVEAAMSSKTLKKWNHLLQKGWVELFVPKFSISATYDLGSTLQKMGMRDAFAESADFPGITKDNGLKLSYAFHKAVLHIGEEGTKEGASPEAGSLDQPEVAPLHAVIRLDRTFLLMILEKRTRSVLFLGKVVDPTKE
What is the function of this protein?
Major thyroid hormone transport protein in serum.
What are the official names of this protein?
Thyroxine-binding globulin, Serpin A7, T4-binding globulin.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GSTM7_MOUSE
Sequence: MPMTLGYWDIRGLAHAIRLFLEYTDSSYEEKRYTMGDAPDYDQSQWLNEKFKLGLDFPNLPYLIDGSHKITQSNAILRYLGRKHNLCGETEEERIRVDILENQLMDNRMVLARLCYNADFEKLKPGYLEQLPGMMRLYSEFLGKRPWFAGDKITFVDFIAYDVLERNQVFEAKCLDAFPNLKDFIARFEGLKKISDYMKTSRFLPRPMFTKMATWGSN
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase Mu 7, GST class-mu 7, GSTM-7.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPFA_ASPFU
Sequence: MLRAKLVDDPQIKYASLHNPLPTQLHAYVWPFLIIWPAFFAVYLSPERYDTYIQGQEWTFVWSGSIITAQSLLWLMTKWNINIQTLFTATKARSLDSAQLIKVIPVANAGSAEICPLHCDTMGGKKTFSFLFQKRRFLYYPERQCFAPLSYVLDAEPKPPVKVFQQAQGLTSKEEIDRIQHHYGDNTFDIPVPTFMELFKEHAVAPFFVFQVFCVGLWMLDEYWYYSLFTLFMLVVFESTVVWQRQRTLNEFRGMNIKPYDVWVYRQKKWQELTSDKLLPGDLMSVNRTKEDSGVACDILLIEGSAIVNEAMLSGESTPLLKESIQLRPGDDLIDPDGLDKNAFVHGGTKVLQITHHNSNGEDGSEKARKLSSGVPLPPDNGAVGVVVKTGFETSQGSLVRTMIYSTERVSANNVEALLFILFLLIFAIAAAWYVWQEGVAKDRKRSKLLLDCVLIVTSVVPPELPMELSLAVNTSLAALSKFAIFCTEPFRIPFAGRVDVACFDKTGTLTGEDLVVDGIAGLTLGHEGADVGKDGAHTELAKSANVPLDTTLVLASAHALVKLDEGEVVGDPMEKATLQWLGWTLGRNDTLMSKAAALAGPRTVESVQIKRRFQFSSALKRQSTIATVVTADRKTSKKTKATFVGVKGAPETIRTMLVNTPPHYEETFKYFTRNGARVLALAYKYLSEESELSQGRINGYIREEIEADLIFAGFLVLQCPLKEDAIKAVRMLNESSHRVVMITGDNPLTAVHVARKVEIVDRDVLILDAPEDDMSGTRLVWRSIDDKFNRDVDPTQDLDPEIIETKDICITGYALAKFKGQKAFSTLLRHTWVYARVSPKQKEDILVGLKDAGYTTLMCGDGTNDVGALKQAHVGVALLNGSPEDLAKIAEHYRTTKMKEIYEKQVSMMQRFNQPPPPVPVQIAHLYPPGPRNPHYQKAMEREAQRKGAATLATAGNQTEHIPTITSPGAQALQQSNANLTPQQQRQQQASIAAAGFADKLTSSMLEQELDDSEPPTIKLGDASVAAPFTSKLANVIAIPNILRQGRCTLVATIQMYKILALNCLISAYSLSVIYLDGIKFGDGQVTISGMLMSVCFLSISRAKSVEGLSKERPQPNIFNVYIIGSVLGQFAIHIATLIYLSNYVYSIEPRKSDIDLEGEFEPSLLNSAIYLLQLIQQISTFSINYQGRPFRESIRENKAMYWGLVAASGVAFSCATEFIPELNEKMRLVPFSTEFKVTLTVLMIIDYAGCWIIENVLKNLFSDFRPKDIAVRRPDQLQREMERKKQEELETQAEKERQRKV
What is the function of this protein?
Endoplasmic reticulum (ER) translocase required to remove mitochondrial transmembrane proteins mistargeted to the endoplasmic reticulum (By similarity).  Acts as a dislocase that mediates the ATP-dependent extraction of mislocalized mitochondrial transmembrane proteins from the endoplasmic reticulum membrane (By similarity).  Works in concert with the ER Ca(2+) pump srcA to support ER homeostasis (PubMed:34663092).  With srcA, supports also redox homeostasis and virulence (PubMed:34663092).
What are the official names of this protein?
Endoplasmic reticulum transmembrane helix translocase spfA.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
Protein: DNAK_CROS8
Sequence: MGKIIGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIISADNGDAWLDVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKETGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDINDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTPLITKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEEEIQKMVREAEANAEADRKFEELVQTRNQADHLVHSTRKQVEEAGDKLPADDKTAIESALSALEASLKGEDKADIEAKMQALAQVSQKLMEIAQQQHAQQQAGSADASANNAKDDDVVDAEFEEVKDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MIAB_PROMP
Sequence: MLTKPIQEEEKIYKNSSLGSYWITTFGCQMNKADSERMAGTLEKMGYSRAIDELKADLVLYNTCTIRDSAQQKVYSFLGKQVKRKHSTPKLKLVVAGCLAQQEGESLLRRVPELDLIMGPQHVNNLENLLERVDLGNQVVATEETFISEDITNPRRDSSICGWVNIIYGCNERCSYCVVPSVRGKEQSRYPDAIKSEIESLAHNNFKEVTLLGQNIDAYGRDLPGTTKEGRKENSLTDLLYFIHDVEGIKRIRFSTSHPKYFSKRLINACYELDKVCEHFHIPFQSGNNEILRLMARGYTIEKYKRIIENIRQLMPNASITADAIVAFPGETETQYRETLKLISDIGFDQVMTAAYSPRPNTPAAFWDNQIPEEVKKERLKEINELVETTSRKRNQRYLNNIESVLIEGLNPKNNAQMMGRTRTNRLTFVEISKNIEFNYSYGDEINVKITEARSFSLSGQIYK
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP5G_STAAC
Sequence: MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLFVAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA
What is the function of this protein?
Could be involved in septation.
What are the official names of this protein?
Putative septation protein SpoVG.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.
Protein: RHAD_PECAS
Sequence: MQAILSSWFVQGMIKATSDMWLKGWDERNGGNVSLRLTAEDVTPYESDFSPQPRHEALSQPMPELADCWFIVTGSGKFFRNVQLDPADSLVVLQVDSDGKGYRIFWGLTNGGLPTSELASHFQSHIVRMGVTHGRDRVIMHCHATNLIALSYVLELNTATFTRELWEGSTECLVVFPDGVGIVPWMVPGTDSIGDATSEQMKRHSLVLWPFHGIFGTGPTLDEAFGLIDTAEKSAEVMVKVRSMGGKKQTISTEELIALGKRFGVTPLEAALRV
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_SOLM1
Sequence: MPPIVAIVGRPNVGKSTLFNRLTRGRRAITHDLPGVTRDRLEAPAEIEGRFVTLVDTGGMDYEAEESLARQIVEQAEAALVTADVVLFLVDGKAGRTALEDDLAERLRRLGKPVIVAVNKVDGLERVAAMTADFHAWGLPLLAISAAHGQGMAELAEAIAERLPEAEPYDPDAPLVQTVLRLAVLGRPNAGKSSLINALVGESRLIVSDIAGTTRDAVDVVVHQKGKRYLFVDTAGVRKRTRITDGLERYSVAKALSSAKRADVAVVVIDATGGVGVQDKRLISFLDSERKAFLVAVNKTDLVPQKDMLALQKDIARELRMCSHVPVLYMSAAKGKGVAKVLPQAEAIWAECQIRIGTGELNRAMRASLDKHQPPLVNGRRAKFYYLTQAADAPPTFVFFVSDTERVRDSYIKYLENSLRKLFGIATAPVKVVCRASHKPKDER
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: TRPD_BRUME
Sequence: MADLKPYIAKAASGEPLPLGDAKAAFDIMMSGQATPSQIGGFLMALRVRGETVPEIAGAVASMRSRMIPVIAPDDAMDIVGTGGDQSGSYNVSSCTAFVVAGAGVPVAKHGNRALSSRSGAADALAALGINIEADADTIGRSISEAGLGFMFAPMHHSAMRHVGPSRVELGTRTIFNLLGPLSNPASVKRQLVGVFAPQWLEPLAHVLKELGSETAWVVYGDGLDEMTTAGTTQVAALENGQIRTFEITPEEVGLRRCSPAELKGGEAAENAKALLGVLEGKDSAYRDIVLLNSGAALVVAGKAENLKDGIAQAVQSIDSGAALAVLQKVIAVSNDKPA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: LPXD_PSESM
Sequence: MSITIKLGQLAEFLGATLRGDKDKDITGLATLEEAGPGQISFLAKPQYRKYLVDTQAAAVLLKPADADGYTGDALLVPDPYLAYARISHFFDPKPKSSAGVHPTAVIAEDAQVDPAASIGAFAVIESGARIAANVTIGAHCFIGARSEIGEGGWLAPRVTLYHDVRIGKRVVIQSGAVLGGEGFGFVNDKGVWQKFAQIGGVTLGDDVEIGVNTAIDRGALSDTRIGNGVKLDNQIHIAHNVQIGDHTAMAACVGISGSAKIGKHCMLAGGVGLVGHIDICDGVYITGMTMVTHSITEPGSYSSGTAMQPSAEWRKSAARLRKIDDMARRLQKLEKAVETVTCADNRSSDG
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: END4_VIBC3
Sequence: MYEKLIGAHVSASGGVELAPVRAHEIGANAFALFTKNQRQWAAKPLEASSIRAFKANCKKWGFGSEAILPHDSYLINLGAPEPEKLDKSRAAFVDEMLRCDQLGLTLLNFHPGSHLQQVSEEACLATIAESINLAHRQVPNVIAVIENTAGQGSNLGWRFEHLAAIIDQVEDKERVGVCLDTCHTFAAGYDLRTKAACDETFAEFERVVGMHYLRAMHINDSKGKLASRVDRHHSLGMGEIGWECFEYIAQDARFNGIPLILETIDPDIWATEIATLRKFSTQKEN
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: RDRP_MCMVK
Sequence: MATLPSIHAFWKLWWPTFSEERKMTVVQALRNGLTRKLFQITQIAQQILRWPPYIRERMTSSLGQSLVKTFQTLLGIRKALSRLCLTRNMNVDIFTMLLIPFKFLSQLCSQIVASANFVIQTFRHGLSRGLCLARCRNPETMRSGWSKHTLQMQNCSSTSPLMTPFQPQIARDLSNPHGLWMSTRNKLTRTGGSAIQQTSRYVRLAVRFSLLAAGAYISCVLARKALKEYVYRWELKSDQELPTREQSQISQVEQAMEQNGAMMVMKLNGPTAPILSLQDCLTKHVLVPEIVDEEGTVTQKEQSTFLIREFGPAVRNLVTLAKLEFGGIPKKTTANELTVWRFLVRKCEHANMNPTDSRTAISMALPYVFMPCRTDVGRASIPLRDESIEICRQYRAQFVEETPLRRVFNNPLSGKAWRNWVRHLGGLDDPALFQELKXGCLEEWLGVQSRRTRARHPKLRSHFKDTRHKTRRVFRIAGLGNLYEFGVHNNSAVNLERGLMERVFYVKDDKGELVSCPEPISGIFWKNLKGFRNSIVHHVGHRHPVSRETFLAYYTGPKRTMYEKAVNSLYEMPVSYDDAKLKTFVKAEKINLTKKADPVPRVIQPRAPRYNVELGRYLRPVEHPIYHAIDKIWGGPTIMKGYSVEQIGRHIENAFRSFTDPVAIGFDASRFDQHVSVEALRWEHSVYSRIYGYPELLTQLLRWQIHNRGTAYASDGAFNYQVDGKRMSGDMNISLGNCILATAITHDFVTKLGIPARLINNGDDNVLICPAVEVGRVRQELYRHWLNYGFEVISEEPVYILEQVEFCQMRPVFDGTQYTMMRDPRTTMSKDAYAVTPFNTPTAARRWMRAVGECGLSLTGGLPVKQEYYTALVKHGLDPKNIKQGKDFDSGLYYLSKLSNRKWQEVQESARYSFWLAFGYTPDEQRALEEYFKSWTPTFEWSTTGILAEIPECLLLKHNPLPPT
What is the function of this protein?
RNA-dependent RNA polymerase that plays an essential role in the virus replication.
What are the official names of this protein?
RNA-directed RNA polymerase, 111 kDa protein, Protein p111.
What is the protein family that this protein belongs to?
Belongs to the tombusviridae RNA polymerase family.
Protein: CRL_SHIDS
Sequence: MTLPSGYPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNVKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADDFRDEPVKLTA
What is the function of this protein?
Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes.  Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32.
What are the official names of this protein?
Sigma factor-binding protein Crl.
What is the protein family that this protein belongs to?
Belongs to the Crl family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1IA2_LOXIN
Sequence: DVEERADKRRPIWIMGHMVNAIAQIDEFVNLGANSIETDVSFDDNANPEYTYHGIPCDCGRSCLKWENFNDFLKGLRSATTPGNAKYQAKLILVVFDLKTGSLYDNQANEAGKKLAKNLLKHYWNNGNNGGRAYIVLSIPDLNHYPLIKGFKDQLTQDGHPELMDKVGHDFSGNDAIGDVGNAYKKAGISGHVWQSDGITNCLLRGLDRVKQAIANRDSANGFINKVYYWTVDKRATTRDALDAGVDGVMTNYPDVITDVLNESAYKNKFRVASYEDNPWETFKK
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) with high activity (PubMed:16581177, PubMed:9790962).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Shows high hemolytic activity.  Induces dermonecrosis, vascular permeability, edema, inflammatory response, and platelet aggregation (PubMed:16581177, PubMed:17900646).  Also shows cytotoxicity against renal epithelial cells (PubMed:17900646).  In addition, also induces hemolysis in a complement-dependent manner and probably also in a complement-independent manner (PubMed:9790962, PubMed:17900646).  The hemolysis provoked in a complement-independent manner may be composed of several steps (By similarity).  The toxin may bind to erythrocyte membranes, may hydrolyze membrane phospholipids (SM and LPC) thus generating metabolism products that may cause hemolysis, probably by provoking an increase of calcium inside cells (By similarity).  The calcium influx may be due to the opening of L-type calcium channels, since L-type calcium channel blockers inhibit calcium influx (By similarity).  In vivo, is lethal to mice when intraperitoneally injected (PubMed:17900646).
What are the official names of this protein?
Dermonecrotic toxin LiSicTox-alphaIA2aii, Dermonecrotic toxin 2, DT2, LiRecDT2, LiP2, P2, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D 2, SMD 2, SMase D 2, Sphingomyelinase D 2.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily. Class IIa sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NDUA2_MACFA
Sequence: MAAAAASRGIGAKLGLREIRIHLCQRSPGSQGVRDFIEKRYVELKKANPDLPILIRECSDVQPKLWARYAFGQEKNVPLNNFSADQVTRALENVLSGKA
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2, Complex I-B8, CI-B8, NADH-ubiquinone oxidoreductase B8 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA2 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: DNLJ_WOLTR
Sequence: MADLEKMIEEFTKLRDQISYHDVLYHQKSKPEIADAEYDKLKQKLVEMEGQLPGACVTQDGVGAAPDEKFSKIKHREPMLSLENAYDEQGVERFLSRIKRFLIEEEIEVFCEPKIDGLSFSAVYEDGRFVKAATRGDGFIGEDVTRNVATIKGFPRFLQDVQDRLEVRGEIYINNSDFLKLNKDNEFANPRNAAAGSLKQLDVSITANRPLKYFAYSLIGGKEKSQSEVLNRLESLGFCVNEHRSLTNNLSGMLEFYNKVYNCRYSLDYDIDGIVYKVNDLILQSRLGSTHKAPRSALAYKFSAVYAKTKLNKIFIQVGRTGVLTPVADLIPVNIGGVLVSRANLHNQDEIKRKDVREGDIVTIKRAGDVIPQIVRVDKGSRHADAPGFVFPEICPECGGKVQAEGAAIRCSEELTCKAQIIGKLSHFVSKGAFDIFGLGEKQIKFFYDLGLIKQIPDIFNLEERLNEFSLKEQPDWGERSIANLLNAIQNRRVITLDRFIFSLGIRFIGQVAAELLANYYVSYNNWYNSMIKLLSNDAEVGVGGVEKKIAKSFSDELVGIDGIGEKVAESLKSFFSKEHNIKMLKDLTDYLQILSVNSNSSNSVLNNKVIVFTGKLLTMSRGEAKVRAKALGAKVSSNLSAKIDYLVAGEKPGNKYKKAVELGVGILNEDQWYRMINSEVSE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SPEE_SALA4
Sequence: MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVETITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEALDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSSEIIQARFHAAGLKCRYYNPAIHAAAFALPQYLHDALSAQ
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C102A_MOUSE
Sequence: MSHGPSPRLAESPQLSKSSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPSLPLTAPALLADGDWESREELRLRELEEARARALQMEKTMRWWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDTLTKELAGARRERQEAQGECEARGRELARLRGVHSAADKTHDGPEPEREQEPVRDIGAERPPGSQELDLVESLLKSRPEEPEGCWDACSVAAGGPRVSSGRQDRNRLPWEDTASTEEDASKLTALRLRLDESQKVLLKEREDKLALSKNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKETHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQNASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHETEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLRRQQQNAPLFGKIRSTRFGTEEAGDGASDLDEDEDLQIQVA
What are the official names of this protein?
Coiled-coil domain-containing protein 102A.
Protein: ATPB_BACCA
Sequence: MTRGRVIQVMGPVVDVKFENGHLPAIYNALKIQHKARNENEVDIDLTLEVALHLGDDTVRTIAMASTDGLIRGMEVIDTGAPISVPVGEVTLGRVFNVLGEPIDLEGDIPADARRDPIHRPAPKFEELATEVEILETGIKVVDLLAPYIKGGKIGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYHEMKDSGVISKTAMVFGQMNEPPGARMRVALTGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTAKGSTTSIQAIYVPADDYTDPAPATTFSHLDATTNLERNVAEMGIYPAVDPLASTSRALAPEIVGEEHYQVARKVQQTLQRYKELQDIIAILGMDELSDEDKLVVHRARRIQFFLSQNFHVAEQFTGQPGSYVPVKETVRGFKEILEGKYDHLPEDRFRLVGRIEEVVEKAKAMGVEV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: BCCP_SHIFL
Sequence: MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVMQQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAFIEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxyl carrier protein of acetyl-CoA carboxylase, BCCP.