PharMolix/UniProtQA huggingface dataset:
Protein: PSBK_ACAM1
Sequence: MEAVLLLAKLPEAFSVFSPIVDVMPVIPLFFLALAFVWQAAVGFK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: EIF3A_DROVI
Sequence: MARYTQRPENALKRANEFIEVGKPLRALDTLQEVFRNKRWNYAYSETVIEPLMFKYLYLCVELKKSHIAKEGLFQYRNMFQLVNVNSLENVIRGYLKMAEEHTEAAQAQSSAAVAVLELDDLDNIATPESILMSAVCGEDAQDRSDRTILLPWVKFLWESYCQCLELLRVNTHCEALYHDIARMAFQFCLKYNRKSEFRRLCDKLRKHLEDICKSSNQTTGVSINKVETQQLCLDTRLYLLDSAIQMELWQEAYKAIEDIHGLMAMSKKTPVPKTMANYYQKLAMVFSKAGNQLFHAAALLKLFQLTRELKKNLTKDDLQRMAAHVLLATLSIPLPSAHPEFDRFIEADKSPLEKAQKLAVLLGLPQPPTRVSLIREVVRLNVPNLVSDEFRNLYNWLEVDFNPLNLCKRIQSIVDTIESSETENTLLTPYIQSLKDVTIMRLIRQISQVYESIEFKRLLELAPFCNIFELEKLLVESVRHNDMQIRIDHQRNSIYFGTDLTESQREYRPDGPTLQSMPSEQIRSQLVNMSTVLTRAVSIVYPNRERDQRAKLRTQMVQHYHEIKDREHQRILQRQKIIEDRKEFIEKQNNAREEEEARRHEEESRKAKLAEQKRLEQEQEERERKRHENEIQAIKEKSLKEKVQQISQTAHGKKMLSKLDEEGIKKLDAEQIAMRESEELQRERKELQSKLKSQEKKIDYFERAKRIEEIPLFEKYLAEKNVKDKEFWEATEQTRIENAIAERKDAVSQQDRLKRMYPDRDEYLEALKKERASLYVEKLKKFDIALAEERKKRLADRVVRRREERRQAYLRAKEEERFRKEEEIRHAREAEERAAAEARRLEREAEDEKRRQQYEKQRAKEEEAERKIQEDRERLAREVAVERERSEKERDVWRPRADRVERPSAAPAGGASEWRRNAPPTDRNERTDRGDRNDRNDRNDRNDRNDRNDRNDRNDRPERAERKENDGGADSSWRVRREPESQRGTGAGMDRSERGGGGAPSGRDDKWRRGGDRSERLGGDRDRDSFRRNDGPRRDDDRGGFRRDDQPQRETGSNWRDSPRQNDRDNRRTTGERRDVRGAGPKEGGGGVSGGGAGGGGGNWRTAPSPREEKAPPKREQAQDKENKAGDDGEWTSVKRR
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 subunit 10.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIS_SALDC
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: YOZF_BACSU
Sequence: MKRVLFSVIVFTAVGFTFCQSKAHALTFTVLPITQKTDQWSVKVSEAKNVKEFTRPHKGEYQVYSLEVKNIGEKAATVDVQLYRNDPNSITRFSLFGCPDENCVKPKEDSKMLAESLNDGSPLKFNHFMLADKASELEVVIIWTQKGQEGRNLKQTFKFTEDGVN
What are the official names of this protein?
Uncharacterized protein YozF.
Protein: PEPE_SHESM
Sequence: MTVNALLLSSSRVGDTPYLSHAIPFIKPLTTNAQKWIFIPYAGVSMSYDTYLASVVAGLSELRLDISGIHQHPDPRQAIKDADGILIGGGNTFHLLHELYKYDLVHLIREEVMNGKPYIGWSAGSNVSGLSIRTTNDMPIIEPPSFTALNIVPFQLNPHYSNYRAPGHNGETRAQRLLEFTRVDPITPVVGIVEGSALWRQGETLSLLGDNPAYLFCGEQQEIPIPVGSDLSHLLK
What is the function of this protein?
Hydrolyzes dipeptides containing N-terminal aspartate residues.  May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids.
What are the official names of this protein?
Peptidase E, Alpha-aspartyl dipeptidase, Asp-specific dipeptidase, Dipeptidase E.
What is the protein family that this protein belongs to?
Belongs to the peptidase S51 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DDL_CUPPJ
Sequence: MSFVANPKIDPKSLGKVGVLYGGRSAEREISLMSGSGVLAALQSRGVDAHGFDPATQSVAELAAAGFDRVFIALHGRYGEDGTMQGLLEQLGVPYTGSGVLASALAMDKQATKRLWMTHDLSTPRFAMLYADTDFDAVVADLGLPLIVKPAREGSSIGLSKVTDASQMREAFEKAAALDNDVIAETFIDGAELTCPLVGEGATAEALPVIRIVAPDSNYDYQNKYFTDDTQYLCPSGLSAEVEREVQQLAVQAYRVLGCRGWARADVMLRADGKPFLLEMNTSPGMTGHSLVPMAARAAGISYEDFVMQVVAAATLDLHPNEHWKPE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGTB_NEIMA
Sequence: MQNHVISLASAAERRAHITDTFGVRGIPFQFFDALMPSERLEQAMAELVPGLSAHPYLSGVEKACFMSHAVLWKQALDEGLPYIAVFEDDVLLGEGAEKFLAEDAWLQERFDPDSAFIVRLETMFMHVLTSPSGVADYCGRAFPLLESEHWGTAGYIISRKAMWFFLDRFAALPSEGLHPVDWMMFGNPDDRERMPVCQLNPALCAQELHYAKFHDQNSALGSLIEHDRCLNSKQQRRDSPANTFKHRLIRALTKISREREKRRQRREQLIGKIIVPFQ
What is the function of this protein?
Adds the second galactose to the lacto-N-tetraose chain in lipooligosaccharide (LOS).
What are the official names of this protein?
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtB.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 25 family.
Protein: TRPE_MYCBO
Sequence: MHADLAATTSREDFRLLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAENGRSWSRWSFIGAGAPTALTVREGQAVWLGAVPKDAPTGGDPLRALQVTLELLATADRQSEPGLPPLSGGMVGFFAYDMVRRLERLPERAVDDLCLPDMLLLLATDVAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTAALGQPLPSTVATFSRPEPRHRAQRTVEEYGAIVEYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYLLQVPNSDGAVDFSIVGSSPEALVTVHEGWATTHPIAGTRWRGRTDDEDVLLEKELLADDKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEGRTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADSNGSYEYNEARNKARAVLNAIAAAETLAAPGANRSGC
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: SLIMP_DROME
Sequence: MLSLRSVLKHCLSAKKTCSRNISALYITGDKANENYVTLQPYMDFNKTFGERQFLEQSISSRGLDIRLETVLSKYEKYKTHHAQLSKVAEERERVTKRLKELTKSGSSAVQLEELKEHGKSLRNELKALKQTLYPIEDDFIHDYLHLPNLLHVQCPVGGEEKLLYRHGIPKSENKTTSHLARQELVHFVDNNRYYLMEQAALFDVNAMQSLARYFVNHGHFIQTANPDFVRCVLLEANATPLSDYHLVQEEHLQNKINTAYLTGGASFESYLGAMTKLCVYPSVLPLRYVCCGRSYNRAEADLYGPIPSLYTATQTNAVQIFVATQTDNEADSQLEHILNLATDFYKALDIPFRISYATAADLTPAESIRAVIEVYAPSLQRYVCVGRISNYGDFVSKRILFSTRREKHYDFLHMVGGPVLYTSRLIAALVEHGVRLEDCKLLGSISQKPVHQQDLQQFKDLFT
What is the function of this protein?
Essential protein which may play a role in mitochondrial morphogenesis and function.  Has transfer RNA (tRNA)-binding activity and can bind tRNA(Ser) but does not have serine--tRNA ligase activity and does not bind ATP.
What are the official names of this protein?
Serine--tRNA synthetase-like protein Slimp, Seryl-tRNA synthetase-like insect mitochondrial protein.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
Protein: TYF1_TREPE
Sequence: MNMCTDGKKYHSTATSAAVGASAPGVPDARAIAAICEQLRRHVADLGVLYIKLHNYHWHIYGIEFKQVHELLEEYYVSVTEAFDTIAERLLQLGAQAPASMAEYLALSGIAEETEKEITIVSALARVKRDFEYLSTRFSQTQVLAAESGDAVTDGIITDILRTLGKAIWMLGATLKA
What are the official names of this protein?
Antigen TyF1.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
Protein: DADA_PARP8
Sequence: MRVVVLGSGVVGVTSAYYLARAGHEVTVIDREAGPALETSFANAGQISPGYAAPWAAPGVPLKAVKWMFQKHAPLAIRLDGTQFQLQWMWQMLQNCTSARYAVNKGRMVRLAEYSRDCLQALRAETGIQYEGRTGGTLQLFRTQQQLDGAAKDIAVLEEANVPYELLMPADLARAEPALAATSHKLTGGLRLPGDETGDCQLFTTRLAALAEQLGVKFRYNTPIDALAMEGGRIAGVKCGNEMVRADNFVVALGSYSTQFLSGLVKIPVYPLKGYSITAPIVDAKSAPVSTVLDETYKIAITRFDDRIRVGGMAEIVGFDKKLKQARRETLEMCVNDLFPGGGDTSKATFWTGLRPMTPDGTPIVGRTPVSNLFLNTGHGTLGWTMSCGSGQLLADLISGKRPAIQSGDLSVHRYLGETAGQTRPAYA
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: NUOB1_CHLAD
Sequence: MGIEEKAGNLGIVTTTLETVVNWGRTNAMWPLLFGLACCAIEMMGAQASNYDLSRFGMELNRASPRQADLMIVAGRVSRKMAPVVRRLYDQMPEPKWVIAMGDCAACGGIFNNYAIVQGVDEVVPVDVYVAGCPPRPEALIDGIMMLHQKVMREKLSGKKEAPIRIDQPLVQVK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NDHI_HYMFF
Sequence: MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTIFNLPEIKT
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit I, chloroplastic, NAD(P)H dehydrogenase subunit I, NDH subunit I, NADH-plastoquinone oxidoreductase subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: CKLF7_HUMAN
Sequence: MSHGAGLVRTTCSSGSALGPGAGAAQPSASPLEGLLDLSYPRTHAALLKVAQMVTLLIAFICVRSSLWTNYSAYSYFEVVTICDLIMILAFYLVHLFRFYRVLTCISWPLSELLHYLIGTLLLLIASIVAASKSYNQSGLVAGAIFGFMATFLCMASIWLSYKISCVTQSTDAAV
What are the official names of this protein?
CKLF-like MARVEL transmembrane domain-containing protein 7, Chemokine-like factor superfamily member 7.
What is the protein family that this protein belongs to?
Belongs to the chemokine-like factor family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LNT_CHLMU
Sequence: MFKSVLYIGLSWVLVCFAQPDISTLASVICCMCGYGLLWRGLLSLVDSSSWRKIWCLAFFWTWSVEGFHFSWMLEDFYVGTSIYFVWCLLISYLAVTFASFSCLVVLCFRKQYWGALFWLPGVWVAIESVRYYGLLSGVSFDFIGWPLAATAYGRQFGSFFGWAGQSFVVIATNLGCCSVLVFRKSFSYGLWLVCCAFPYFLGGTYYEYVRRHFSNEEVLRVAIVQPGYSPHMQGARTASAIWSNLVSLCQGICPPVDVIVFPEVSVPFGLHRQAYSFHENQQVLESLVPNKFWNEFFTNLDWIRALSERFQCAVIMGMERWEDKNGVMHLYNAAECLSLQGEVTSYDKRILVPGGEYIPGGKFGFSLCKAFFPEFALPFQRLPGEKSGIVQITERIKAGISICYEETFGYAILPYKRQKADILVNLTNDGWYPHSRLPLVHFYHGVLRNQELGMPCIRACHTGVSAAVDSLGRIVGVLPWESKTCPVCPDVLQVSVPVYSYPTIYAKFGDAPLLFVAVSSVLGVVGYFLKRRGKTLTGSDI
What is the function of this protein?
Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
What are the official names of this protein?
Apolipoprotein N-acyltransferase, ALP N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ELV1B_XENLA
Sequence: MSNGYEDHMDDVCRDDIGRTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYLNAKDAERAINTLNGLRLQSKTIKVSFARPSSETIKDANLYISGLPRTMTQKDVEDMFLPFGHIINSRVLVDQATGLSRGVAFIRFDKRSEAEEAIASFNGHKPPGSSEPITVKFAANPNQSKNMALLSQICHSPARRFGGPVHHQAQRFRFSPMGVDHMSSISSVNVASSASSGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKTLQVSFKTSKSHK
What is the function of this protein?
RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability.  Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (By similarity).  Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs.  Acts cooperatively with cribp to stabilize AU-rich sequence (ARE)-containing mRNAs.  May play a role during gastrulation.  Required for the vegetal localization of vg1 mRNA.
What are the official names of this protein?
ELAV-like protein 1-B, Protein ElrA-B, ElrA.
What is the protein family that this protein belongs to?
Belongs to the RRM elav family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cell cortex. Note=Enriched at the vegetal cortex in stage III and IV oocytes. Shows very weak nuclear localization.
Protein: GLB73_CHITH
Sequence: MKFFAVLALCIVGAIASPLTADEASLVQSSWKAVSHNEVDILAAVFAAYPDIQAKFPQFAGKDLASIKDTGAFATHATRIVSFLSEVIALSGNESNASAVNSLVSKLGDDHKARGVSAAQFGEFRTALVAYLSNHVSWGDNVAAAWNKALDNTYAIVVPRL
What are the official names of this protein?
Globin CTT-VIIB-3.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: ARF_ASHGO
Sequence: MGVSFSKLFSNLFGHKEMRILMVGLDGAGKTTVLYKLKLGEVVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFRNTEGIIFVVDSNDRSRIAEAREVLQRMLNEDEIRNAVLLVFANKQDLPEAMSAAEITEKLGLHSIRQRPWYIQATCATSGEGLYEGLEWLSTNLKNQA
What is the function of this protein?
GTP-binding protein involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: CAP13_FLASX
Sequence: MEKIYTWLKTNSYIVHHVSTSLNIISFIIVLIWIFESTIKEKLNIIFTVNLEAIVVFISILIVGLNQLLQKLLIEAEYSPAFALAVGYFKNFIFPAITQIKENGEVNPKICIYKPKHFDELTSTNIDMIKAELTNKKYNLSEINLSLKGARARDILTLNKKSKIHSYFDFPNTLLSLYSYVDFKIASSNNNSSELKKKKFVELLIEQFYLKLNELIQENNLTNNITFCDKNLQGL
What is the function of this protein?
Binds cyclic dinucleotides: binds c-di-GMP (synthesized by the cognate CdnE encoded upstream in the same operon), cyclic 3'3'-cyclic GMP-AMP (3'3'-cGAMP) but not cUMP-AMP (PubMed:32877915).  The effector protein for this CBASS system, its activity is stimulated by c-di-GMP and leads to cell death (Probable).
What are the official names of this protein?
CD-NTase-associated protein 13, Cap13, TM-STING, FsSTING.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the bacterial STING family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARG39_MOUSE
Sequence: MESSGSAACCPVLQQRARWERKRVCTARELLETERRYQEQLGLVATYFLRILKAKGTLRPPELQTLFGTWELIYAASLELLPYLEEGQWGLGLQGFCPHLELYAQFAANAERSQTTLQAQLKKNKRFRRFVKLQEGRPEFRGLQLQDLLPLPLQRLQQYENLVVALAENTVPNSPDYQQLTRAARLVSETAQKVHAIGQSQKNDQHLLRVQALLSGRKAKGLTSGRWFLRQGWLLVVPPTGEPRPRMFFLFSDVLLMAKPRPPLHLLKSGTFVCRALYPMSQCHLSRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSQWHHSLTLAIRSQKSSTHRSVTAT
What is the function of this protein?
Promotes cell proliferation.
What are the official names of this protein?
Rho guanine nucleotide exchange factor 39.
What are the subcellular locations of this protein?
Cell membrane.
Protein: RS12_MESH2
Sequence: MPTISQLAKGCRVKKTWKSKVPALNMLYNSLHKKELKLSAPFKRGVCTRVATMTPKKPNSALRKFARVKLSNGIEVNAYIPGEGHNLQEHSIVLIRGGKVKDLPGIRYHIVRGTQDTTGVAKRSQGRSKYGAKRPKKSK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: DNLJ_THESC
Sequence: MTLEEARKRVNELRDLIRYHNYRYYVLADPEISDAEYDRLLRELKELEERFPELKSPDSPTEQVGAKPLEATFRPIRHPTRMYSLDNAFNFDELKAFEERIGRALGREGPFAYTVEHKVDGLSVNLYYEDGVLVWGATRGDGEVGEEVTQNLLTIPTIPRRVKGVPERLEVRGEVYMPIEAFLRLNEELEEKGEKIFKNPRNAAAGSLRQKDPRITARRGLRATFYALGLGLEESGLKTQLDLLHWLREKGFPVEHGFARAEGAEGVERIYQGWLKERRSLPFEADGVVVKLDELSLWRELGYTARAPRFAIAYKFPAEEKETRLLQVVFQVGRTGRVTPVGILEPVFIEGSVVSRVTLHNESYIEELDVRIGDWVLVHKAGGVIPEVLRVLKEKRTGEERPIRWPETCPECGHRLVKEGKVHRCPNPLCPAKRFEAIRHYASRKAMDIGGLGEKLIEKLLEKGLVKDVADLYRLKKEDLLGLERMGEKSAQNLLRQIEESKGRGLERLLYALGLPGVGEVLARNLAAHFGTMDRLLEASLEELLQVEEVGELTARGIYETLQDPAFRDLVRRLKEAGVVMEAKERGEEALKGLTFVITGELSRPREEVKALLRRLGAKVTDSVSRKTSYLVVGENPGSKLEKARALGVPTLTEEELYRLIEERTGKPVETLAS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: PSBN_GNEGN
Sequence: METANLVTISISCLLVSLTGYAIYTSFGRPSEQLKDPFEDHED
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CYSZ_ECO7I
Sequence: MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMGGAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAPFNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIPGIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRIALRTRKITNMQFGALTSLFTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR
What is the function of this protein?
High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake.  Provides the sulfur source for the cysteine synthesis pathway.
What are the official names of this protein?
Sulfate transporter CysZ.
What is the protein family that this protein belongs to?
Belongs to the CysZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROB_STRS2
Sequence: MKLTVNLPNTPYDILIQRGSLAQTGAWVKELWKPQKIAIITDDHVGSLYRETVQSSLEQAGFETIVFEFPEGEASKNLDTVNQAYEFLVKNGMTRSDGIIALGGGVVGDLAGFVASTYMRGIHFLQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFCQPDGVLIDPDTLKTLGKRELIEGMGEVVKYGLIDDVELWETLDQLDGSVESILEHADYIIYHSCEVKRKVVVEDELDNGVRLYLNFGHTIGHAIEATAGYGQVMHGEAVAIGMVQISRAAEKKGLMPAGMTAKIIAMCEKFGLPTTHQPWNVDELYASLTHDKKTRGKTIKLVIVPQLGQAAIHQIPMEEMLEFLQV
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 3DHQ_MAGO7
Sequence: MPSQKPTILLLNGPNLNLLGTREPQIYGSTTLSDVQERCLALASSLDVELRHVQSNHEGALVDAIHALRRDLPLAGVVINPGAFTHTSVAIRDALLGVGAPFVELHVSNVHAREAFRHHSYLSDKAVAVICGMGVDGYAVAVEFMAKRLKAQAAAKL
What is the function of this protein?
Is involved in the catabolism of quinate.  Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway.
What are the official names of this protein?
Catabolic 3-dehydroquinase, cDHQase, 3-dehydroquinate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: EASD_ASPFU
Sequence: MASVESRIIAITGGASGIGAATCRLLAERGAAVLCVCDISPKNFDDLKISIKKINPSTKVHCATVDVTSSVEVRQWIEGIISDFGDLHGAVNAAGIAQGAGMRNTPTIAEEVDEEWTRIMNTNLNGVFYCTREEVRAMKGLPATDRSIVNVGSIASVSHMPDVYAYGTSKGACAYFTTCVAADAFPLGIRINNVSPGVTNTPMLPQFAPMAKTFEEIEESYKKEGLSLIEAEDVARTIVWLLSEDSRPVFGANINVGACMP
What is the function of this protein?
Chanoclavine-I dehydrogenase; part of the gene cluster that mediates the biosynthesis of fumiclavanine C, a fungal ergot alkaloid (PubMed:15933009, PubMed:26972831).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (PubMed:15870460).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by EasD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (PubMed:20039019, PubMed:20526482, PubMed:21409592).  EasA reduces chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline (PubMed:20526482).  EasG then catalyzes the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine (PubMed:20526482).  Hydrolysis of festuclavine by easM then leads to the formation of fumigaclavine B which is in turn acetylated by easN to fumigaclavine A (PubMed:26972831).  Finally, easL catalyzes the conversion of fumigaclavine A into fumigaclavine C by attaching a dimethylallyl moiety to C-2 of the indole nucleus (PubMed:19672909).
What are the official names of this protein?
Chanoclavine-I dehydrogenase easD, ChaDH, Ergot alkaloid synthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: PHS_BRUSU
Sequence: MARNRLTESEMNEALRALDGWQKVDGREAITRSFKFKDFSTAFGFMAQAALYAEKLDHHPEWFNAYNRVDVTLATHSENGVTELDIKMARKMNAIAG
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.