PharMolix/UniProtQA huggingface dataset:
Protein: ARNA_SALDC
Sequence: MKAVIFAYHDMGCQGVQAVLDAGYEIAAIFTHADNPAENTFFGSVSRLAAELGIPVYAPDNVNHPIWVDRIAEFAPDIIFSFYYRNLLSEEILHLAPAGAFNLHGSLLPAYRGRAPLNWVLVNGESETGVTLHRMVKRADAGEIVASQRVAIAQDDVALTLHHKLCQAARQLLNSILPTMKCGDIPSVPQRESDATYYGRRRPEDGLIDWHKPVSTVHNLVRAVAAPWPGAFSYNGSQKFTIWSSRICPDAQGALPGSVISVSPLRVACADGALEIITGQAGDGITVQGSQLAQTLGLVAGARLNRPPATSGKRRIRVLILGVNGFIGNHLTERLLNEENYEVYGMDIGSNAISRFLLHPRFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRVVFPSTSEVYGMCTDASFDEDKSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLRFTLFRPFNWMGPRLDSLNAARIGSSRAITQLILNLVEGTPIKLIDGGQQKRCFTDIRDGIEALFRIIVNEGDRCDGKIINIGNPDNEASIQELATLLLDSFDKHPLRCHFPPFAGFQVVESRSYYGKGYQDVAHRKPSIDNARRCLGWEPSIAMRDTVEETLDFFLRSVDVAERAS
What is the function of this protein?
Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto-arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido-arabinose (UDP-L-Ara4FN).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Bifunctional polymyxin resistance protein ArnA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
Protein: YCF46_GRATL
Sequence: MSFKNNLKLLLSTQNVLIYILNSEEERLEYKIHLMIRQNIKKTIYCWNFIDGYYNNPNYLNKAIRNPLQAIEFIEQLNFPTSTIFFLKDFHVFINDISVIRKIKNLSRFLKQANSSIIISASEMQVPSLLKDFITVLEFPLPNYEEINLELHRLFKIMNVDSSIYSEYFHDLTLAYRGFSIEKIRISIAKLLTSNLSSTHLIKNILYEKRQLIEQTDVLEFYAVDYSFDNVGGLNVLKDWLNKRSKAFSKQAKNYGLTVPKGILLIGIQGTGKSLIAKAISGQWNLPLLKLDMGKIFASLVGQSEERMRHMIKTAEQSSPCILWIDEIDKCFTRLNNYTDSGTNGRVLSTMLTWLSEKKKPVFVIATANQVLSLPSELLRKGRFDEIFFLNLPSLEEREKIFQIHLMKFRPLSWRKYDIKYLSKLTDQFSGAEIEQAIIEAMYNAFYEKREFSTQDIINAINNFVPLAFTDTCNISAIQDWAISGKIRMAS
What are the official names of this protein?
Uncharacterized AAA domain-containing protein ycf46.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. Highly divergent.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PLSX_SHEPW
Sequence: MTNLTLALDAMGGDFGPRITVPATLQALRLNPLLKVILVGDQVQIDEYLVPAEPEIKRRIEIKHTTEVVTMSDRPVHALRNRKQSSMRIAIELVRDGKAQACLSAGNTGALMAMSKVLLKTLPGIDRPALVSCLPAVNNTPVYLLDLGANVSCDSETLFQFAVMGSVLSETVDKTVSPKVALLNVGIEEIKGNDQVQQAGQLLQQIPQVNYTGFIEGDEIYSGNVDVIVCDGFVGNITLKTSEGIARLLTHQLKKGLTEGFFVRILAKIIAPRIHSLLNQMNPDHYNGASLIGLRGIVVKSHGCADEAAFLQAICLAVTEAQRRLPQMIEDRLESILLDINS
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: NPD1_GEOKA
Sequence: MTITSWLAASRHTVVLTGAGMSTESGLPDFRSPRTGLWARFNPSELATIDALYHRRESFVEFYQYRIRTLQQCQPHDGHRLLADWERRGIVQTIVTQNVDGFHQEAGSRRVIELHGSLRTVHCQRCGESKPSFVYLHGVLTCECGGVLRPSVVLFGEPLPEKAITEAWEAAQQADLFLVLGSSLQVSPANQLPLVAKRNGAKLVIINWEPTELDDLADAVIHQRKIGEVLNELNEQLAEVDP
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase 1, Regulatory protein SIR2 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG29_KLUMD
Sequence: MNNENTKVYIRVSGKRPEGFIDPKPFEWGFKRDKILWTRISKMESLEDMDWKELCQDLGAPESFLKKRSYMLFQKHLKLLSEQMSDSPRMRSPLDTRNSVDETILQNLQASKILNNRFDVPNNETLDTTTNKNNEESGSDLSSSLSVSKSALEDALMDRLQL
What is the function of this protein?
Plays a role in autophagy (PubMed:26442587).  Functions at the preautophagosomal structure (PAS) in order to form normal autophagosomes under starvation conditions (By similarity).  Also plays a role in mitophagy (By similarity).
What are the official names of this protein?
Autophagy-related protein 29.
What is the protein family that this protein belongs to?
Belongs to the ATG29 family.
What are the subcellular locations of this protein?
Preautophagosomal structure. Note=Localizes also to other perivacuolar punctate structures (By similarity).
Protein: BGL40_ARATH
Sequence: MAHRRLIMTMTKMMMMVTMMMMMDKTCICADISRGSFPKGFVFGTASSAFQHEGAVKAEGRGPTIWDTFSHTFGKITDFSNADVAVDQYHRYEEDVQLMKNMGMDAYRFSISWTRIFPNGVGHINEAGIDHYNKLINALLAKGIEPYVTLYHWDLPQALHDRYLGWLNPQIINDFAAYAEVCFQRFGDRVKHWITFNEPHTFAIQGYDVGLQAPGRCTILFKLTCREGNSSTEPYIVGHNVILTHATVSDIYRKKYKAKQGGSLGIAFDVMWFEPESNKTEDIEAAQRAQDFQLGWFLDPLMFGDYPSSMRSRVGSRLPVFTGSQSSLVKGSLDFVGINHYTTYYARNNATNLIGTLLHDAVSDSGTVTLPFKGLSTIGDRASSIWLYIVPRGMRSLMNYIKHRYGNPPVFITENGMDDPNSILISRKDALKDAKRIKYHHDYLSSLQASIKEDGCNVKGYFVWSLLDNWEWAAGYSSRFGLYFVDYRDNLKRYPKDSVHWFTSFLNSTS
What are the official names of this protein?
Beta-glucosidase 40, AtBGLU40.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: LGT_HELPG
Sequence: MNAWNTIYDQFNPIAFSLGGIEVHWYGLAYACAIVIAFYMALRMIQKDPERFPIERKEFESYFLWAELGIVLGARIGYVLIYEPNSSYYLTHFWQIFNPFDRHGNFVGIRGMSYHGGLVGFLIASYLYSRKDLKKLLIYLDLIAISLPLGYVFGRIGNFLNQELVGRVVPKDSHLGQIIGIMVDNQLRYPSQLIEAFLEGVIVFLMVLWAKKHTKTHGLLIVVYGLGYSLMRFIAEFYREPDSQMGVYFLNLSMGQILSLFMVVVSLGILLYATRHSKKIKENQ
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NGF_XENLA
Sequence: MSMLYYTLLIAILISVQAAPKTKDHAPARSSAKSRIPHHTHRTKSLHHSHGKLEAKEPSYFRNVTVDPKLFRKRKFRSPRVLFSTQPPPLSEDFQHLEYLDDEESLNKTIRAKRTVHPVLHKGEYSVCDSVSMWVGEKTKATDIKGKEVTVLGEVNINNSVFKQYFFETKCRDPKPVSSGCRGIDAKHWNSYCTTTHTFVKALTMEGKQAAWRFIRIDTACVCVLSRKGRT
What is the function of this protein?
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems.  It stimulates division and differentiation of sympathetic and embryonic sensory neurons.
What are the official names of this protein?
Nerve growth factor, NGF.
What is the protein family that this protein belongs to?
Belongs to the NGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y787_RICPR
Sequence: MNKLLKLFFITIIIYNNIAFAKETGFYMGAAIGIVEPVVRKFRHKYSNTGIIFQICIAGK
What are the official names of this protein?
Uncharacterized protein RP787.
Protein: FBX9_RAT
Sequence: MAEAEEDCHSDAVRVGDEGHESPAERDLQAQLQMFRAQWMFELTPGVGSSNVESRPCRAGRSSILKAAADKGRQELAKEEKARELFLKAVEEEQNGALYEAIKFYRRAMQLVPDIEFKITYTRSPDGDGVGSSYIEDNEDASKMADLLSYFQQQLTFQESVLKLCQPELETSQTHISVLPMEVLMYIFRWVVSSDLDLRSLEQLSLVCRGFYICARDPEIWRLACLKVWGRSCMKLVPFSSWREMFLERPRVRFDGVYISKTTYIRQGEQSLDGFYRAWHQVEYYRYIRFFPDGHVMMLTTPEEPPSIVPRLRTRNTRTDAILLGHYRLSQDADNQTKVFAVITKKKEEKPLDHKYRYFRRVPVQEADHNFHVGLQLCSSGHQRFNKLIWIHHSCHITYRSTGETAVSAFDIDKMYTPLFFARVRSYTAFSERPL
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins and plays a role in several biological processes such as cell cycle, cell proliferation, or maintenance of chromosome stability.  Ubiquitinates mTORC1-bound TTI1 and TELO2 when they are phosphorylated by CK2 following growth factor deprivation, leading to their degradation.  In contrast, does not mediate ubiquitination of TTI1 and TELO2 when they are part of the mTORC2 complex.  As a consequence, mTORC1 is inactivated to restrain cell growth and protein translation, while mTORC2 is the activated due to the relief of feedback inhibition by mTORC1.  Plays a role in maintaining epithelial cell survival by regulating the turn-over of chromatin modulator PRMT4 through ubiquitination and degradation by the proteasomal pathway (By similarity).  Regulates also PPARgamma stability by facilitating PPARgamma/PPARG ubiquitination and thereby plays a role in adipocyte differentiation (By similarity).
What are the official names of this protein?
F-box only protein 9.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_SORMI
Sequence: MTNLRKTHPLMKIVNSSFIDLPAPSNISSWWNFGSLLGVCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDVLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSIVVLALVPFLHTSKQRSIMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVIMPITSVSEDNLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: OMP1_COXBU
Sequence: METTTKLAIGVSALCCLASAAFAGGPDIPMIDMNGFHIGLGFGYKSYTYDQVGTVTVTTNGGTVLSVLHPVSASITQFGPVGELGYTFASDWWIAGVKAQYQYDNVRSVHIMDAPLVGSNYSYRTRLGSHLTAMLLAGIKVNEANAVYLEAGYSTVWGKTTLFGPGPVAVSMKNRLNGGIAGIGWRHYFMNNVFLDLSYDYALYRSKSNSVTLSSATASAEGTAIGVSGTVQNPKRVAINGITATVNYLFNI
What is the function of this protein?
Able to form a pore in lipid bilayers.
What are the official names of this protein?
Outer membrane protein P1.
What is the protein family that this protein belongs to?
Belongs to the Coxiella porin P1 (CPP1) (TC 1.B.43) family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein. Note=Outer membrane location shown for Nine Mile phase I, but not that it actually spans the membrane.
Protein: NUOB2_BURM7
Sequence: MANHPLTLEKDGFIVTTLDAAMAAAQKNSLWYMTFGLACCAVEMMHAAGARYDMDRFGMIPRASPRQCDLMIVAGTLTNKMAPAMRRVYDQMAEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALVYGLMQLQRKVAERSTHSRPKLFARP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 2, NADH dehydrogenase I subunit B 2, NDH-1 subunit B 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DPOL_WHV4
Sequence: MHPFSRLFRNIQSLGEEEVQELLGPPEDALPLLAGEDLNHRVADALNLHLPTADLQWVHKTNAITGLYSNQAAQFNPHWIQPEFPELHLHNDLIQKLQQYFGPLTINEKRKLQLNFPARFFPKATKYFPLIKGIKNNYPNFALEHFFATANYLWTLWEAGILYLRKNQTTLTFKGKPYSWEHRQLVQHNGQQHKSHLQSRQNSSMVACSGHLLHNHLSSESVSVSTRNLSNNISDKSQKSTRTGLCSYKQIQTDRLEHLARISCGSKITIGQQGSSPKTLYKSISSNFRNQTWAYNSSRNSGHTTWFSSASNSNKSRSREKAYSSNSTSKRYSPPLNYEKSDFSSPGVRRRITRLDNNGTPTQCLWRSFYNTKPCGSYCIHHIVSSLDDWGPCTVTGDVTIKSPRTPRRITGGVFLVDKNPNNSSESRLVVDFSQFSRGHTRVHWPKFAVPNLQTLANLLSTNLQWLSLDVSAAFYHIPISPAAVPHLLVGSPGLERFNTCLSSSTHNRNNSQLQTMHNLCTRHVYSSLLLLFKTYGRKLHLLAHPFIMGFRKLPMGVGLSPFLLAQFTSALASMVRRNFPHCVVFAYMDDLVLGARTSEHLTAIYSHICSVFLDLGIHLNVNKTKWWGNHLHFMGYVITSSGVLPQDKHVKKISRYLRSVPVNQPLDYKICERLTGILNYVAPFTLCGYAALMPLYHAITSRTAFIFSSLYKSWLLSLYEELWPVVRQRGVVCTVFADATPTGWGIATTYQLLSGTFAFPLPIATAELIAACLARCWTGARLLGTDNSVVLSGKLTSFPWLLACVANWILRGTSFCYVPSALNPADLPSRGLLPVLRPLPRLRLRPQTSRISLWAASPPVSPRRPVRVAWSSPVQNCEPWIPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: PKHA8_MOUSE
Sequence: MEGVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMDLIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFAENTENLKTKMSELRLYCDLLVQQVDKTKEVATAGVTDSEEGIDVGTLLKSTCNTFLKTLEECMQIANAAFTSELLYHTPPGSPQLAVLKSSKMKHPIIPIHNSLERSMELNSCENGSLSIEVNGDEEILMKTKSSLYLKSTEVDCSISSEENTDDNVTVQGEIMKEDGEENLESHDKDPAQPGSDSVCSPESPWEDNEEVIPTFFSTMNTSFSDIELLEDSGIPTEAFLASCYAVVPVLDKLGPTVFAPVKMDLVGNIKKVNQKYITNKEEFTTLQKIVLHEVEADVAQVRNSATEALLWLKRGLKFLKGFLTEVKNGEKDIQTALNNAYGKTLRQHHGWVVRGVFALALRAAPSYEDFVAALTIKEGDHQKEAFSAGMQRDLSLYLPAMEKQLAILDTLYEIHGLESDEVV
What is the function of this protein?
Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN).  Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation.  Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids.  Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability.  Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation (By similarity).
What are the official names of this protein?
Pleckstrin homology domain-containing family A member 8, PH domain-containing family A member 8, Phosphatidylinositol-four-phosphate adapter protein 2, FAPP-2, Phosphoinositol 4-phosphate adapter protein 2.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane. Membrane; Peripheral membrane protein. Note=Binds through its PH domain to PtdIns(4)P and ARF1, and subsequently localizes to TGN exit sites.
Protein: RS3_ANAPZ
Sequence: MGQKSNPIGLRLKIVGTWDSLWYANRDYATKLHEDLLLRSFVKKTFHHAAVSKVVIARKVDAVIINIHSARPGVIIGKKGVDIDRIKQKIAKMVNHEVELHIVEVKKPDLKAVLIAENIAQQLEKRVSFRRAMKRGVQNCLKMGAKGVKVSCAGRLGGAEIARTEWYKEGSVPLHTFRANIDYSCVEAKTIYGIVGVKVWVYVGDSRAVVE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: LEU1_NOSS1
Sequence: MTTKPEKIIIFDTTLRDGEQCPGATLNIDEKLAIAKQLARLGVDIIEAGFAFASPGDFEAVHKIAQTVGTQSGPVICSLARARHDDIKAAAEAIKPAAKGRIHTFIATSDIHLQYKLKKTRPEVIAIAEEMVAYAKSFTDDVEFSPEDAGRSDPEFLYQVLERAIAAGATTINIPDTVGYTTPSEFGAIIKGIKENVPNIDQAIISVHGHNDLGLAVANFLEAVKNGARQLECTINGIGERAGNAALEELVMAMHVRRQYFNPFLGRHPDSEEALTNIDTKQIYKTSRLVSNLTGMLVQPNKAIVGANAFAHESGIHQDGVLKNKLTYEIMDAQLIGLTDNQIVLGKHSGRNAFRTRLKELGFELSETELNKAFVKFKEVADKKKEISDWDLEAIVNDEIQQAPDLFRVELVQVSCGSNARPTATVTLRTPDGEELTDAAIGTGPVDAVYKAINRVVNVPNQLIEFSVQSVTAGIDAIGEVTIRLRYESRVFSGHAANTDIIVASAQAYVNALNRLYASLQTQDKQTEVTA
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: C4AA1_DROME
Sequence: MFVEKVLERTTNLELCSILILLVISLSIYTFYATLNTYLRSVLLSLRLTGPPSLPFLGNCMLVTDKDLMRRCAGKAFDLYGSLVRIWVLLFPFFAVLEPEDLQVILSSKKHTNKVFFYRLMHNFLGDGLITSSGSKWSNHRRLIQPAFHHNLLEKFIDTFVDASQSLYENLDAEAVGTEINIAKYVNNCVLDILNEAVLGVPIKKRGQDVAMMEDSPFRQGKIMMPARFTQPWLLLDGIYHWTKMANDELNQKKRLNDFTRKMIQRRRQIQNNNNGNSERKCLLDHMIEISESNRDFTEEDIVNEACTFMLAGQDSVGAAVAFTLFLLTQNPECQDRCVLELATIFEDSNRAPTMTDLHEMRYMEMCIKEALRLYPSVPLIARKLGEEVRLAKHTLPAGSNVFICPYATHRLAHIYPDPEKFQPERFSPENSENRHPYAFLPFSAGPRYCIGNRFAIMEIKTIVSRLLRSYQLLPVTGKTTIAATFRITLRASGGLWVRLKERDHPLIAH
What is the function of this protein?
May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
What are the official names of this protein?
Probable cytochrome P450 4aa1, CYPIVAA1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein: INT5_DROME
Sequence: MLRQNLLDQLKHFIETVSNGHSCPQLLTSPNLIKLALGFLEELPATRDIVFEYFALLAEISVQLYVSPEMADPKTGMPVSQVKLAGNRQQQQRAPEYEAFNLVKTALQSLVWKGPPAWSPLIANWSLELVAKLSDKYTQRRMTITASCNYWLECSAMHGLMTLINSCFRKLTQPEEEACVEIMLNAFHRFPMTFDWIVARLGGCFPYKIIMQILQCGIKRFVDDYRCHLDSEAGILDYMTSCHEQHLRAAFREMLREGFAPKKPLDVAVVPFLLITTNYSDTILQSLVNVLVEIYTEDMCEVIVQKAPLWLSNKMFAGMQPTLNNAVLRLNERGATLLLTAAKMAEKYVWCQDFLDNSMQELEQWVLNQRNFPLLADLAYEETKYMLWKSCLSTNLFEQQTAVRLLLVVSSQHPNIYYQTISQLLKKSYAQNPNGIGALIRLLGGQSGMVNFPGFTPGFKMVLEDITLDVQVNNRLPVPPGTPTEAFNTFSNLNILARMHKSKNVAPYIKAQHLNQALNECLPKILQIFDCTVNKLVLRIDRDAAERIADKFRAQQSKNSNNNNELCNGKDYGKRTKLEPGEDKVDDEDATRMRLAHLIVDLLNNIEAGSRTTVLRTPLVLKLATLSVKYFFVGLTEKTVIRRAAASHRSYTLLQRQCSARKIARTVCLRELVERALFYHGHLLGQLEVYQLDELEIPEHEHLILQNLHTSSGANSNRSVLHSGIIGRGLRPVLPPSERNCDAEKQALYLKALNACCADLEKPNNVEGYSLVSLLLVELVSTDVMYNGLPFPDEEFTRVTMERDMLIRRAFINSPVLWAVLGLIAGHRPALCYSSVLLRALCATCLHHWRGKNVNRFQPTAANDELMLCTKKMLQLLAMSQLIPPPLTNLHLIIEHFESAEIALLLRECIWNYLKDHVPSPALFHVDNNGLHWRNTNTQLAKVPPQYVDPLRHLMQRKLSTLGPHYHQMFIMGELMEGDSEPDPTARLQIVEID
What is the function of this protein?
Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box-dependent processing (PubMed:21078872, PubMed:23097424).  Involved in the 3'-end processing of the U7 snRNA, and also the spliceosomal snRNAs U1, U2, U4 and U5 (PubMed:21078872).  May mediate recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity).
What are the official names of this protein?
Integrator complex subunit 5, Protein oocyte maintenance defects.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 5 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Nucleus. Cytoplasm.
Protein: SAP18_ARATH
Sequence: MAEAARRQGGGRPLPPPPRGVNQQPPRPKPEPVDREKTCPLLLRVFTKSGGHHTSEDYAVRGKEPKDEVQIYTWKDASLRELTDLVKEVSVAARRRNARLSFAFVYPNNKGGYNVREVGETMAYPNRKQPDDSKTLSELPFEIGDYLDVAIY
What is the function of this protein?
Links the histone deacetylase complex to transcriptional repressors bound to chromatin.  Involved in the tethering of the SIN3 complex to core histone proteins.
What are the official names of this protein?
Histone deacetylase complex subunit SAP18, 18 kDa Sin3-associated polypeptide.
What is the protein family that this protein belongs to?
Belongs to the SAP18 family.
Protein: RN148_BOVIN
Sequence: MSLLRITSSAHSSASSRLWRLGIFLLLSLPDSKGKAIWTAHLNITFQVGSRLISELGESGVFGNHSPLERVSGVVVLPEGWNQNACNPMTNFSRPGQTDPWLALIERGGCTFTRKINVAAEKGANGVIIYNYPGTGNKVFPMSHQGTENIVAVMIGNLKGMELLHLIQKGVYVKIIIEVGRMHMPWLSHYIMSLFTFLTATVAYLFLYCAWRPRGPNFSTRRQRQLKADVRKAIGKLQLRVLQEGDKELEPDEDNCVVCFDIYKPQDVVRILTCKHIFHKACIDPWLLAHRTCPMCKCDILQT
What are the official names of this protein?
RING finger protein 148.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y945_SINMW
Sequence: MDISRAEQRILHHLAQGGRIEITREGKTITEIRCFTRDGWVYPGVDLELFRKLKRKRAIRSSAGKPYRITERGVRSELNNR
What are the official names of this protein?
UPF0386 protein Smed_0945.
What is the protein family that this protein belongs to?
Belongs to the UPF0386 family.
Protein: PURK_STAAW
Sequence: MSFNKLKFGATIGIIGGGQLGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLGQKCDVITYEFENISAQQLKLLCEKYNIPQGYQAIQLLQDRLTEKETLKSAGTKVVPFISVKESTDIDKAIETLGYPFIVKTRFGGYDGKGQVLINNEKDLQEGFKLIETSECVAEKYLNIKKEVSLTVTRGNNNQITFFPLQENEHRNQILFKTIVPARIDKTAEAKEQVNKIIQSIHFIGTFTVEFFIDSNNQLYVNEIAPRPHNSGHYSIEACDYSQFDTHILAVTGQSLPNSIELLKPAVMMNLLGKDLDLLENEFNEHPEWHLHIYGKSERKDSRKMGHMTVLTNDVNQTEQDMYAKFEGSN
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
What are the official names of this protein?
N5-carboxyaminoimidazole ribonucleotide synthase, N5-CAIR synthase, 5-(carboxyamino)imidazole ribonucleotide synthetase.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: SPEH_SULIK
Sequence: MGVELAFPKVVGKQVYGSLYDCDENVLKDTKRLEQIIKEAADVGNMNILDIKSWKIGEGVSVVAIILESHITIHTWPEYKFATVDVYSCGPHTSPLKAFNYIVEKLGAKKYTINEADRSSEF
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: Y6627_DICDI
Sequence: MTDKYNDWVKNKKHNNYNMAEDPLYYIKSNWVIERQLSKGSFGQVYKAHKKLDPNFVCAIKVIQYCKFTMKEVDYLKKLNDPKFVKYYSLEFNNSKTYAYIIMEFIEGESMKSIIENKKFSDIEIKEIIKELLKALVYLNDKGIMHRDLKPENIMFQNQNQNQNQNNKINLKLIDFGLSKAINENIINKTVKLQTISSVGTTLYMAPEILLNNKGSNSSLDIWSLGCIIVEMKWGLNQLCLQRPNNIPVFPVNSLFTEILNLCFQTEPSKRIKSHQLIKHPFFNDENEQFYNDNKEYFDFLKENERDSYIEIHNTESIGSNSTCSINEIRFENLYLIQSTYENQYPIKTITLHEKYTGISKLSHLNSKFKIIYLFLILLFLMTILVNLNRHVQTKFSIIQRDNIFLSITPESNPIKKPSPTQSSDYNQYSEGSQSSYESSSSSESSSESSSSESSSSESSSSSESQSSEINYSSNSNDLQPTDSSTTDPPVTDPPITDPPITDPPVTDPPITEPPVTETPKPTINPFFNTPVFICSQKIDQCLTVLNSQDLEFIDKKGRDQSMVLEYDGNAEQTFSIREKGGMYICLSGEHYHFSEKLKGRLNANKDGRDCTFNLITQFNIDKQANLYSFRSPNDQYIQSDETTRFISTKPGGLGSQSQFFIYFSHSLGPN
What are the official names of this protein?
Probable serine/threonine-protein kinase DDB_G0286627.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.