PharMolix/UniProtQA huggingface dataset:
Protein: ATPD_RUEPO
Sequence: MSEPASISAGIAQRYATAIFAIAQDNNDLKGLETGINDLTAALGESADLRSLIASPLVSRAEQEAAITAVAKKMKLNPVLANALSLMAQKRRLFVLPQLLTALRDALAEARGEVTAEVASAKALTKTQIEKLTKTLSEKVGKSVTINATVDESLIGGLVVKVGSKMIDSSIRSKLNSLQNAMKEVG
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ALFL5_ORYSI
Sequence: MDGGSGGPYTSRTAEEVFRDFRGRRAGMIKALTTDVEKFYQLCDPEKENLCLYGYPNETWEVTLPAEEVPPEIPEPALGINFARDGMNEKDWLALVAVHSDSWLLAVAFYFAARFGFDKEARRRLFNMINNLPTIFEVVTGAAKKQTKEKAPNSTNKPNKPSSKMQPRPESHSKAPKPPAPPKDDDESGDEYADEEEEERDNTLCGSCGTNDGKDEFWICCDSCERWYHGKCVKITPARAEHIKHYKCPDCGNKRARA
What is the function of this protein?
Histone-binding component that specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes.
What are the official names of this protein?
PHD finger protein ALFIN-LIKE 5.
What is the protein family that this protein belongs to?
Belongs to the Alfin family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRPC_CHLCH
Sequence: MTYLDRILEHKQIEVAALKKEQPRQRYEELQAELEAPRNFSASLKRPANKGVRLIAEIKKASPSRGLIVQDFDPLAMAQRYQELGAAAFSVLTDQQFFQGSNDYLRQVKGAFKLPVLRKDFIVDALQIFEARLLGADAILLIVAALESSQLRDYLQLSAELGLSALVEVHDGAELDEALQQGATILGVNNRNLKDFSVDINTSIKLRPSIPSDMIAVAESGLKRAADIDAVNAAGFDAVLIGEGLHISTELRSLIWT
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: LEXA_STRAW
Sequence: MNEATSHEGPKRSLPGRPPGIRADSSGLTDRQRRVIEVIRDSVQRRGYPPSMREIGQAVGLSSTSSVAHQLMALERKGFLRRDPHRPRAYEVRGSDQSSSVQPTDTAGKPAASYVPLVGRIAAGGPILAEESVEDVFPLPRQLVGDGELFVLKVVGDSMIEAAICDGDWVTVRRQPVAENGDIVAAMLDGEATVKRFKREDGHVWLLPHNSAYQPIPGDEATILGKVVAVLRRV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: Y3645_MYCBO
Sequence: MTENLTVQPERLGVLASHHDNAAVDASSGVEAAAGLGESVAITHGPYCSQFNDTLNVYLTAHNALGSSLHTAGVDLAKSLRIAAKIYSEADEAWRKAIDGLFT
What are the official names of this protein?
EspC protein homolog.
What is the protein family that this protein belongs to?
Belongs to the EspC family.
Protein: RIMP_EXIS2
Sequence: MTNVTEKVEQLAKPIVEREGMELVDVEFVKEGADWFLRVSIDKDGGVDLEDCVNINEKLSEALNQDDPIDEPYYLDVASPGAERPLKKTEDFEKAIGKHVYIKTHDPVKDATEFEGTLLTYSEEMLELEVRVKTRKLKIEIPVNKIAMARLAVVF
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_TREPA
Sequence: MGKIIGIDLGTTNSCVAIMEGGEPVVIQNAEGGRTTPSIIGFTSDGGRVVGQPAKNQMVTNPEHTIYSIKRFIGSRFNELTGEAKKVPYKIVPQGDDVRVEVEGKLYSTQEISAFILQKMKKTAEDYLGEAVTEAVITVPAYFNDAQRQATKDAGKIAGLDVKRIINEPTAASLAFGFNKDSKREKIIAVYDLGGGTFDISILELGDGVFEVKSTNGDTHLGGDDFDARIVQWLEQGFKSDTGIDLGNDRMALQRLREAAEKAKIALSSSASTEINLPFITADANGPKHLQRTLSRSEFEKMTDDLFERTKEPCRKALKDAGISADRIDEILLVGGSTRMPKVAHVIKDVFGKEGSKGVNPDEAVAIGAAIQGGILGGDVKDVLLLDVTPLSLGIETMGGVFTPLISRNTTIPTRKSQVFSTAADGQTAVSIHVLQGERGMANQNRTLGNFDLVGIPPAPRGVPQIEVTFDIDANGIVHVSAKDLGTGKEQHIRIESSSGLSESEIDRMVKEAEANAESDKREREKIEARNVADSLIYQTEKTLKEAGDGVNAADRARIDEAIAELKTVLSGDDVASIKAKTEILQQASYKIAEEMYKRQAAAGAAAGKKSDAPSGNEAEGGDVDYEVVKDEDSK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: EA30_VICFA
Sequence: MEFAHLTVLSLFCLAFVGITATSSGEDYWQSIWPNTPLPKTFSDLLIPSGKTNSLPIKSEELKQYSTLFFEHDLHPGKNFILGNTNSVGSIIRPFTKSRQGVTDSIWLANKEKQSLEDFCYSPTAIAEHKHCVSSLKSMIDQVISHFGSTKIKAISSNFAPYQDQYVVEDVKKVGDNAVMCHRLNFEKVVFNCHQVRDTTAYVVSLVASDGTKTKALTVCHHDTRGMNPELLYEALEVTPGTVPVCHFIGNKAAAWVPNHTADNLCVM
What are the official names of this protein?
Embryonic abundant protein VF30.1.
Protein: ERA_CLOBK
Sequence: MFKSGFVTIVGRPNVGKSTLLNAIMKEKLSIVSCRPQTTRNNIQTILTEDNYQLVFVDTPGIHKPKHKLGEYMVKSASDAMKDVDLVLFLINPDEKPGRGDLFIIEQLKEVKVPVFLVLNKIDENPQEKVAETLKTYSELMEFEEIIPISALKGKNIDLLKELMFKYIPEGPQYYPEDMIIDQNERFIVAEIVREKALRLLSEEVPHGIAVEILQMKKNEKGTYHIEGNILCEKNSHKPIIIGKGGSKLKKISQYARQDIEAFLQSKVYIRLWVKVKEEWRDNQSLLKELGYKKMK
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: NRDR_BACAA
Sequence: MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVSLRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: RLMH_METEP
Sequence: MRLLVVAIGRLKNGPERDLAARYRERAVALGKGLGVTACDLTEIPESRARRSADRIAEEAAAILALVPADAAVIACDERGRSDWPSERIADKIGAWRDAGRSTLVLVVGGADGLHETVRGRADHILAFGAATLPHGLVRVLALEQVYRALTILAGHPYHRGDPEA
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CEMA_NEPOL
Sequence: MLAQSIRDCILWIRKTPDRALRAAKEAADLYQNIQQESRIYQNLRGANDATVILYLDKELSQYERTVKLRLQEFRVSSALLRGFEASQTESAETKKMVEEIEMAISRSQFLRSILSASSVKTHKPLAFEKTGIIPRSIPRTFDRLRRELLASSEDLVVQEFRISRYQTLTSLKFLASLIWIPWIVSWFLRVWWLEPTITMFWNQDQTQLFLHRSQEERALSDMRAFQEKVYFEVLVGEAPDPTPEVLQRRIQAKARDLAEASNQNSIESLANLGSDILACLILLAMLSLEKTKIAVLKSFLDELIYSLNDATKAFFLILVTDVFVGFHSTHGWEVILELLFAHFGFPESKKFIFMFVATFPVLLDTVFKYWIFRYLNHISPSTVAVYHNMNE
What is the function of this protein?
May be involved in proton extrusion.  Indirectly promotes efficient inorganic carbon uptake into chloroplasts.
What are the official names of this protein?
Chloroplast envelope membrane protein.
What is the protein family that this protein belongs to?
Belongs to the Cema family.
What are the subcellular locations of this protein?
Plastid, chloroplast inner membrane; Multi-pass membrane protein.
Protein: NRAM_I57A1
Sequence: MNPNQKIITIGSVSLTIATACSLMQIAILATTVTLHFKQHECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPEVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNGTIHDRIPHRTLLMNELGVPFHLGTKQVCVAWSSSSCHDGKAWLHVCVTGDDRNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIKEGKIVHISPLSGSAQHIEECSCYPRYPDVRCICRDNWKGSNRPVIDINMEDYSIDSSYVCSGLVGDTPRNDDSSSNSNCRDPNNERGNPGVKGWAFDNGDDVWMGRTISKDSRSGYETFKVIGGWSTPNSKSQVNRQVIVDNNNWSGYSGIFSVEGKSCINRCFYVELIRGRPQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: VATA_STRPZ
Sequence: MNQGKIITVSGPLVVASGMQEANIQDICRVGHLGLVGEIIEMRRDQASIQVYEETSGIGPGEPVVTTGCPLSVELGPGLISEMFDGIQRPLDRFQKATDSDFLIRGVAIPSLDRKAKWAFIPKLSVGQEVVAGDILGTVQETAVIEHRVMVPYKVSGTLVAIHAGDFTVTDTVYEIKQEDGSIYQGSLMQTWPVRQSRPVAQKLIPVEPLVTGQRVIDTFFPVTKGGAAAVPGPFGAGKTVVQHQIAKFANVDIVIYVGCGERGNEMTDVLNEFPELIDPNTGQSIMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYSVAIMADSTSRWAEALREMSGRLQEIPGDEGYPAYLGSRIAEYYERAGRVRTLGSQEREGTITAIGAVSPPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYQDDVGSYIDRKQQSNWSNKVTRAMAILQREASLEEIVRLVGLDSLSEQDRLIMAVARQIREDYLQQNAFDSVDTFTSFPKQEAMLTNILTFNEEASKALSLGAYFNEIMEGTAQVRDRIARSKFIPEENLEQIKGLTQKVTKEIHHVLAKGGI
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The V-type alpha chain is a catalytic subunit.
What are the official names of this protein?
V-type ATP synthase alpha chain, V-ATPase subunit A.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: BIOB_SALAR
Sequence: MARHPRWTLSQVTELFEKPLLELLFEAQQIHRQHFDPKQIQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKNAGSTRFCMGAAWKNPRERDMPYLEQIVQGVKAMGLETCMTLGMLNESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVREAGIKVCSGGIVGLGETVNDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPAEDKDLQLFRKLGLNPQQTRVLAGDNEQQQRLEQTLMTPDTDDYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: CCPR_YEAST
Sequence: MTTAVRLLPSLGRTAHKRSLYLFSAAAAAAAAATFAYSQSQKRSSSSPGGGSNHGWNNWGKAAALASTTPLVHVASVEKGRSYEDFQKVYNAIALKLREDDEYDNYIGYGPVLVRLAWHTSGTWDKHDNTGGSYGGTYRFKKEFNDPSNAGLQNGFKFLEPIHKEFPWISSGDLFSLGGVTAVQEMQGPKIPWRCGRVDTPEDTTPDNGRLPDADKDADYVRTFFQRLNMNDREVVALMGAHALGKTHLKNSGYEGPWGAANNVFTNEFYLNLLNEDWKLEKNDANNEQWDSKSGYMMLPTDYSLIQDPKYLSIVKEYANDQDKFFKDFSKAFEKLLENGITFPKDAPSPFIFKTLEEQGL
What is the function of this protein?
Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Cytochrome c peroxidase, mitochondrial, CCP.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion intermembrane space.
Protein: FLAW_BACSU
Sequence: MAKILLVYATMSGNTEAMADLIEKGLQEALAEVDRFEAMDIDDAQLFTDYDHVIMGTYTWGDGDLPDEFLDLVEDMEEIDFSGKTCAVFGSGDTAYEFFCGAVDTLEAKIKERGGDIVLPSVKIENNPEGEEEEELINFGRQFAKKSGCAV
What is the function of this protein?
Low-potential electron donor to a number of redox enzymes.
What are the official names of this protein?
Probable flavodoxin 2.
What is the protein family that this protein belongs to?
Belongs to the flavodoxin family.
Protein: DER_MICAN
Sequence: MKLPVVAIIGRPNVGKSTLVNRIAGDQQAIVFDQPGITRDRTYQPAFWCDRDFQIVDTGGLVFNDDSEFLPLIREQALIALAEASVAIFVVDGQGGITAGDREIAAWLRQQNVPILLAVNKCESVEQGILQATEFWELAIGEPFPISAIHGSGTGELLDAVIKYLPPAAEIPENEEIKVAIIGRPNVGKSSLLNALTGQQRAIVSPISGTTRDSIDTLIEREGQVYRLIDTAGIRRKKNVDYGAEFFSINRAFKAIRRSDVVLFVIDVLDGVTEQDLKLAGRIIEEGRAVVLVVNKWDAVEKDTYTINTYTKMLQDRLYFMDWAEMIFVSAMTGQRVTKILELVDIAAESHRRRVSTSVINDVIEEAVKWHNPPTTRGGKQGKLYYGTQVSSQPPTIALFVNDPQRFNDNYRRYIEGQFRQQLGFKGTPIRLIWRGKPAREVEKTVNRATKV
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: SYA_SHIB3
Sequence: MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDNKGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRVVEDLVNAQIRRNLPIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGSTIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_CHLTE
Sequence: MKITVLGAGSWGTTLAMLLANKGHEVRLWAHRPEFARALEADRENKRYLKGVLFPDNLRVVENLHDAVETAEMIVTAVPSHALRETAAAFAHLPLDGKIIVNVAKGIEQHTGKRMSEVLLEALPRIAPEQIAVLYGPSHAEEVARQQPTTVVACSVSEATARRVQEAFHTSSFRVYVNTDLIGVEIAGSVKNVIAIAAGISDGLGFGDNAKAAIITRGLAEISRLSSKLGADPLTLSGLSGIGDLVVTCLSQHSRNRYVGEQIGKGRKLDEVIGEMSMVAEGVLTSKAVVKLAERLGVEMPISQAVYEMLYENKPAPQAILELMERDPKPEHY
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL9_CYAP4
Sequence: MGKRIQLVLNQDVYKLGRNGDLVEVAPGYARNYLLPKAMAYVATPGVLKQAERRREQERQRQLELKQAAEKQKQVLEGVGTLTIAMPVGEKEALFGSVTAQDVADLIQSATGQEIDRRTLTLPEVRKLGTYTAEIKLHTEVTAAVKITVVAE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: GLMU_VIBPA
Sequence: MKFSAVILAAGKGTRMHSNMPKVLHTLAGKPMVKHVIDTCTGLGAQNIHLVFGHGGDQMQTTLADETVNWILQADQLGTGHAVDQASPRFEDDEKILVLYGDVPLISPETIENLLDAQPTGGIALLTVMLDNPTGYGRIIRKNGPVVAIVEQKDASEEQKQIKEINTGVMVATGGDLKRWLSGLNNNNAQGEYYLTDVIAAAHDEGRAVEAVHPVNAIEVEGVNDRAQLARLERAFQSMQAQKLLEQGVMLRDPARFDLRGELQCGMDCEIDANVIIEGNVSLGDNVIIGTGCVLKDCEIDDNTIVRPYSVIEGATVGEECTVGPFTRLRPGAELRNDAHVGNFVEVKNARIGEGSKANHLTYLGDAEIGQRTNIGAGTITCNYDGANKFKTIIGNDVFVGSDSQLVAPVTIADGATIGAGTTLTKDVEEGELVITRVKERKITGWQRPVKQK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACFD_ECOLI
Sequence: MNKKFKYKKSLLAAILSATLLAGCDGGGSGSSSDTPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEPIPDPEPTPEPEPEPVPTKTGYLTLGGSQRVTGATCNGESSDGFTFKPGEDVTCVAGNTTIATFNTQSEAARSLRAVEKVSFSLEDAQELAGSDDKKSNAVSLVTSSNSCPANTEQVCLTFSSVIESKRFDSLYKQIDLAPEEFKKLVNEEVENNAATDKAPSTHTSPVVPVTTPGTKPDLNASFVSANAEQFYQYQPTEIILSEGRLVDSQGYGVAGVNYYTNSGRGVTGENGEFSFSWGETISFGIDTFELGSVRGNKSTIALTELGDEVRGANIDQLIHRYSTTGQNNTRVVPDDVRKVFAEYPNVINEIINLSLSNGATLGEGEQVVNLPNEFIEQFNTGQAKEIDTAICAKTDGCNEARWFSLTTRNVNDGQIQGVINKLWGVDTNYKSVSKFHVFHDSTNFYGSTGNARGQAVVNISNAAFPILMARNDKNYWLAFGEKRAWDKNELAYITEAPSLVEPENVTRDTATFNLPFISLGQVGEGKLMVIGNPHYNSILRCPNGYSWNGGVNKDGQCTLNSDPDDMKNFMENVLRYLSDDKWKPDAKASMTVGTNLDTVYFKRHGQVTGNSAAFDFHPDFAGISVEHLSSYGDLDPQEMPLLILNGFEYVTQVGNDPYAIPLRADTSKPKLTQQDVTDLIAYLNKGGSVLIMENVMSNLKEESASGFVRLLDAAGLSMALNKSVVNNDPQGYPNRVRQQRATGIWVYERYPAVDGALPYTIDSKTGEVKWKYQVENKPDDKPKLEVASWLEDVDGKQETRYAFIDEADHKTEDSLKAAKEKIFAAFPGLKECTNPAYHYEVNCLEYRPGTGVPVTGGMYVPQYTQLSLNADTAKAMVQAADLGTNIQRLYQHELYFRTNGRKGERLSSVDLERLYQNMSVWLWNDTSYRYEEGKNDELGFKTFTEFLNCYANDAYAGGTKCSADLKKSLVDNNMIYGDGSSKAGMMNPSYPLNYMEKPLTRLMLGRSWWDLNIKVDVEKYPGAVSEEGQNVTETISLYSNPTKWFAGNMQSTGLWAPAQKEVTIKSNANVPVTVTVALADDLTGREKHEVALNRPPRVTKTYSLDASGTVKFKVPYGGLIYIKGNSSTNESASFTFTGVVKAPFYKDGAWKNDLNSPAPLGELESDAFVYTTPKKNLNASNYTGGLEQFANDLDTFASSMNDFYGRDSEDGKHRMFTYKNLPGHKHRFTNDVQISIGDAHSGYPVMNSSFSPNSTTLPTTPLNDWLIWHEVGHNAAETPLTVPGATEVANNVLALYMQDRYLGKMNRVADDITVAPEYLEESNNQAWARGGAGDRLLMYAQLKEWAEKNFDIKKWYPDGTPLPEFYSEREGMKGWNLFQLMHRKARGDEVSNDKFGGKNYCAESNGNAADTLMLCASWVAQTDLSEFFKKWNPGANAYQLPGASEMSFEGGVSQSAYNTLASLDLPKPEQGPETINQVTEHKMSAE
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of folded proteins across the outer membrane.
What are the official names of this protein?
Putative lipoprotein AcfD homolog.
What is the protein family that this protein belongs to?
To V.cholerae AcfD (VC_0845).
What are the subcellular locations of this protein?
Cell inner membrane; Lipid-anchor.
Protein: COMTB_DANRE
Sequence: MLGVLLCWCLGASVLLYVLYSWLIPAAVQFNGSLALLWHDVIVERALDSLTRSTRPQRLLKAVKQHATRGDPQSVISAIDHFCRHREWAMNVGDEKGCILDSVVSELNPEKVLELGTYCGYSTVRIARLLPPGARLITLEFNPDYAVIARQVIAWAGIEDKVQLVEGASEDWIPRMKEHFGIETFDLVFLDHWKDHYLPDTKLMEGCGLLRKGTVLLADNVICPGVPDYLEYVRNSRSYKSCYFKSHLEYTRAEDGLEKSVFLG
What is the function of this protein?
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
What are the official names of this protein?
Catechol O-methyltransferase B.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVC_RICPU
Sequence: MIILGIDPALGSLGWAVVAKETAQLKYLASGIIRTNSKDAIHHRLAFINSTLEKVILEYQPNMAAIEETFVNTNSVTSLKLGYARGAIMSLIGRYNLDMREFKPNTVKKTVTGYGHAEKDQMLHMIKLLLSGTALITNSDEADAVAIAYTCLVTKNY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NRDR_DESOH
Sequence: MKCPYCGSLDNKVIDSRLSRDDTETRRRRECLECARRFTTYEHVEKAPLMIVKKDGRREEFLKDKVRSGMMSACQKRRISINIIEDFISELEQDLMEMGEHEIPSSIIGEKVMKKLHALDDVAYVRFASVYREFKDVHDFYSELKSLLKKQ
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PTHA_SHIFL
Sequence: MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHCHGELKGALHPGLQFSLGQHRYPVTAVGSVAEDNLRELGHVTLRFDGLNEAEFPGTVHVAGPVPDDIAPGSVLKFESVKE
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of SrlA, SrlB and SrlE is involved in glucitol/sorbitol transport.
What are the official names of this protein?
PTS system glucitol/sorbitol-specific EIIA component, EIIA-Gut, EIII-Gut, Glucitol/sorbitol-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTR15_ARATH
Sequence: MDVHDLSEEAKRGVIHTSEESLDDLCVDFRGRPCRPSKHGGTRAALFVLGFQAFEMMAIAAVGNNLITYVFNEMHFPLSKSANLVTNFIGTVFLLSLLGGFLSDSYLGSFRTMLVFGVIEISGFILLSVQAHLPELRPPECNMKSTTIHCVEANGYKAATLYTALCLVALGSGCLKPNIISHGANQFQRKDLRKLSSFFNAAYFAFSMGQLIALTLLVWVQTHSGMDVGFGVSAAVMAAGMISLVAGTSFYRNKPPSGSIFTPIAQVFVAAITKRKQICPSNPNMVHQPSTDLVRVKPLLHSNKFRFLDKACIKTQGKAMESPWRLCTIEQVHQVKILLSVIPIFACTIIFNTILAQLQTFSVQQGSSMNTHITKTFQIPPASLQAIPYIILIFFVPLYETFFVPLARKLTGNDSGISPLQRIGTGLFLATFSMVAAALVEKKRRESFLEQNVMLSIFWIAPQFLIFGLSEMFTAVGLVEFFYKQSSQSMQSFLTAMTYCSYSFGFYLSSVLVSTVNRVTSSNGSGTKEGWLGDNDLNKDRLDHFYWLLASLSFINFFNYLFWSRWYSCDPSATHHSAEVNSLEALENGEIKDSTTEKPRI
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 4.4, AtNPF4.4, Nitrate transporter 1.13.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.