PharMolix/UniProtQA huggingface dataset:
Protein: KCY_LISW6
Sequence: MTKKICIAIDGPAAAGKSTVAKIVAKKLRFVYIDTGAMYRAVTYIAQKNNLAYEDETAIAQLLQKTVIRFEPGEVQQVFINDENVTEVIRSLEVTNHVSIVAAHPAIREALQERQQIFATEGGIVMDGRDIGTAVLPNAELKIFLLASVEERAERRFKENVAKGFAGDLNQLKKEIEERDHLDYTREHSPLKKAEDAIEVDTTSMSIEEVANKILSLAEQKINN
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL29_FLAJ1
Sequence: MKQSEIKDLSAAELQEKLSQTKKVYADLKMAHAISPIANPLRIRSVRRTVARLATELTKRELQ
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ERB1_PODAN
Sequence: MKSKPVEKKRKVRDEESDSESDDELANGLFDGVLEASEDEEDYIPSDEIDDVDSESEVSEGSEDAEEEEEEEEGDDDALLSDDIPSDDEMGKLSKDAEELEITEPGVDPKPKHQEEEDRNYKVVKDANGGERYVYDEIDPVYDSDDSDAQGPVNTIGNIPLSFYDSYPHIGYDINGKKIMRPATGDALQSLLDTIEVPKGWTGLTDVNTGNPLNLTQEELELVRRVQHGLVPDEGYDPYPDTVEWFTSKQETMPLSAAPEPKRRFLPSKNEAKQVMKLVRAIREGRILPYKPPEEREREEEEKEEVQFDIWQDEEPAAPNPMHIPAPKLPPPGYEMSYNPPEEYLPTEEEREEWEKTDPEDREKEFLPQKFNSLRKVPAWGTLVKERFERCMDLYLAPRVRKNRLNIDPNSLLPKLPSPAELKPFPTVVQTIFRGHEGTVRSIAIDPTGVALATGGSDGTVRVWELLTGRQVWSVKLSSEDPVYTVRWRPTKDAFVLAASAGEDVFLMVPPHSSVTPTLDQASRDVLAAGFGYATNGQQPATAPGKEPAGKWARPGTKLEDAGVLVRVTVRSAVKVITWHRRGDHFATVSPEGQRSSVAIHTLSKHLTQIPFRKLHGLAQTVVFHPLKPLFFVATMRTVRCYDLQKVELVKIVQPGAKWISSLDIHSGGDHLIVGSYDRRLLWHDLDLSNRPHKTMRFHPKAIRAVRFHKGGLPLFADASDDGTLQIFYGKVPNDQLESPTIVPVKQLKGHKVVNQVGVVDIDWHPREPWCVSAGADGTARLWM
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein ERB1, Eukaryotic ribosome biogenesis protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: APGM_METMJ
Sequence: MIAEKVLFLVLDGISDRPCEALDGLTPLAAARTPVLDRLAAEGVCGIMDSVAPGIRPGSDTSHLALLGYPPQEFYTGRGPLEAEGTGIHMTAGMIGFRCNFATVDADGLVTDRRAGRISGTEPLAEAIREGVDLSGLGLEFRFEAGAGHRAALALIGEGLGDKVSSNDPKKEGVQPLTIRPGSDDPADAKTARACNEFIRQSREILDGHPVNVRRMEEGLPPGNLLLIRGAGKMGALPQFPERYGLSGSVISAATLISGIGMVVGLEHIPVPGTTGSVDSDLDAKVRAAIGELGRKDFVLMNIKGADEAGHDGKSIQKRDFIEVIDKALAPLLDLKNTLILVCADHSTPCSVKDHSADPVPVVIRGPGVRIDRTNRFDEVSCAEGGLHRIRGRDLMPIILDLINKSHKYGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: QUEF_RHIE6
Sequence: MMPNTDVSSLSMLGQQTETAKSPEEAVLEKVPSNHAGTDYVVRFTAPEFTSLCPMTGQPDFAHIVIDYIPSEWLVESKSLKLFLHSFRNHGAFHEDCSIYIAKRIVELLDPKWLRIGAYWYPRGGIPIDVFWQTGKPPEGVWLPEQGVATYRGRG
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_CLOK5
Sequence: MDVYRIKKNAEFRAVYKRGKSFSNNLLVLYVYMNRKNVNRLGVSVSKKVGKSVVRNRIKRLIKESFRLNSDYMKVENGYDLVFIARKASNGKSYVEINNSVKNLIKKAGLYK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: SERC_METBF
Sequence: MKPTRVPNNPCFSSGPCAKHPGYSIEELKDTPFGRSHRSNLGKEKLAEAIKKTRDMLGLPDDYLVGIVPASDTGAFEMCLWSMLGCRGVDVLVWESFSKGWATDITKQLKLKDVRVFEAEYGKLPDLKKVDFKNDVVFVWNGTTSGVKVPNGDWIPENREGLTLCDATSAIFAMDIPYHKLDVITFSWQKVLGGEGAHGMLILSPRAVQRLESYTPAWPLPKIFRLTKGGKLNKKIFEGSTINTPSMLANEDWLATLKWAESVGGLKPLIQRTNDNLAVFEAFVAKNNWIHFLAETKEIRSSTSVCFKVDLSDEKLKELIKTLEKEKVAYDIGSYRDAPSGLRIWCGATVEKEDLQCLCEWIEWAYNLVK
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_ECO45
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: PROFG_OLEEU
Sequence: MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-1, Pollen allergen Ole e 2.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: WRBA1_ACICA
Sequence: QNARIAVVYFAGY
What are the official names of this protein?
Flavoprotein WrbA 1.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: PHS_STRM5
Sequence: MADLIPLAQARCVPRKGSDHKLGEARLAELLPQVPGWELSEGGQALLRTFRFKNYYATMAFVNALAWIAHHEDHHPDLGVHYDRAVVRFSTHDVGGLSENDFICAAKTSALTEQLP
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: RNFC_YERPY
Sequence: MFKLFTARQHDKIWDFDGGIHPPEMKLQSSTVPMRIAPLPDQLIIPLQQHLGPEGELRVRAGEQVLKGQPLTVGRGRTVPVHAPTSGMITAIAPHTTAHPSGLAELCVHITPDGEDRWREQQPWADYRQRDKMALLDRIHQAGIAGLGGAGFPTASKLQGGLNGIITLIINAAECEPYITADDRLMQEHADEVITGIHILRHLLQPQQVLIGIEDNKPEAIAALQRALRGQDGIHLRVVPTKYPSGGAKQLTKILTGKEVPFGKHSSSIGVLMQNVGTVVAIKRAVIDDEPLIERVVTLTGDALSSPGNFWARIGTPVLYLLKLAGFKPQNPPMVIMGGPLMGFTLPSLDVPIVKISNCILAPAETEMGLSEPEQSCIRCGLCVDACPAGLLPQQLYWFSRGEEHEKARNHNLFDCIECGACAYVCPSNIPLVQYYRQEKAEIRALDQESARAAEAKARFEAKQARLAREKLARELRHKQAAVKLTDADQQTVDAAVSRLTRQSDGSESVINIPAGQLPDNSAVIAAREARKAQARARQAEKQQARSTEETTDVVDPRQAAVAAAIARVKAKKAAQVQHVTTDVAEAGSEAIAEDPRKAAVAAAIARVKAKKAVQAQHVTTDVAEAGSEAMAEDPRKAAVAAAIARVKAKKAAQAQHVTTDVAEAGSEAMAEDPRKAAVAAAIARVKAKKAAQAINPD
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VPAP_HHV6Z
Sequence: MERGSRDHHRDHRDHREHRELREPPTLAFHMKSWKTINKPLKAFTKLLKENTTVTFTPQPSIIIQSAKNHLVQKLTIQAECLFLSDTEHFLTKTINNHIPLFESFMNIISNPEVTKLYIQHDSDLYTRVLVTASDTCTQASVPCVHGQEVVRDSGKSPLRIDLDHSTVSEVLKWLSPVTKTKRSGKSDAFMAHIIVQVNPPTIKFVTEMNELEFSNSNKVIFYDVNNMRFNLSAKNLQQALSMCAVIKTSCSLRTVAAKDCKLILTSKSTLLTVEAFLTQEQLKEESRFERMGKQDDGKGDRNHKNEDGSALASKQETQYKITNYMVPTKNGTAGSSLFNEKEDSESDDSMHFEYSSNPKRQRCVV
What is the function of this protein?
Accessory subunit of the DNA polymerase that acts to increase the processivity of polymerization.
What are the official names of this protein?
DNA polymerase processivity factor, Phosphoprotein P41, PP41, Polymerase accessory protein, PAP.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae polymerase accessory protein family.
Protein: OTC_STRP2
Sequence: MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYLAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAFHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYIPKV
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXA_SALTY
Sequence: MSSAQRVVITPGEPAGSGPDLVVQLAQRAWPIELVVCADGALLTERAAMLGLPLSLLPYSPDVPAAPQPAGTLTLLPVSLRAPAISGQLTVENGPYVVETLARACDGCLNGEFAALITGPVHKGVINDAGISFTGHTEFFEERSQAKKVVMMLATEELRVALATTHLPLRAIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGKADVGSFITALNLAIKMIVNTQ
What is the function of this protein?
Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
What are the official names of this protein?
4-hydroxythreonine-4-phosphate dehydrogenase, 4-(phosphohydroxy)-L-threonine dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the PdxA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP3_ROTWI
Sequence: MKVLALRHSVAQVYADTQTYLHDDSKDEYENAFLISNLTTHNILYLNYSLKTLKILNKSGIAAVEVQSLDELFALIRCNFTYDYENNIVYLHDYSYYTNNEIRTDQHWITKTDITEYLLPGWKLTYVGYNGKNTRGHYNFSFSCQNAATDDDIIVEYIYSNELDFQNFLLRKIKERMTTSLPIARLSNRVFRDKLFPSIMNIHKKVINVGPRNESMFTFLNFPTIKQFSNGAYIVKHTIKLKQEKWLGKRVSQFDIGQYKNMLNIVTTIYYYYNLYHSKPIIYMLGSAPSYWIHDIKQYSDFTFETWDPLDTPYSTIHHKELFFDKDVNKLRDNSVLYIDIRTDRKNIDWKEWRKIVEQQTVSNLNIAYKYLATGKAKVCCVKLTAMDLELPITAKLLHHPTTEVRSEFYAILDVWDIINIKRFIPKGVFYAFINNITTDNVFIQPPFKLKASPTDYIVALYALSNDFNSRQDVINLINKQKQSLITVRINNTFKDEPKVNFKNIYDWTFLPTDFELKDSVITSYDGCLGMFGLSISLSSKPTGNNHLFIINGTDKYYKLDQYANHMSISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYTFDLKRWIYLHSIGKVAVQGGRYYEHAPIELIYACRSAREFAILQDDLTVLRYANEIEEYINKVYSITYADDPNYFIGIKFNSIPYEYDVKVPHLTLGVLFISDNMIHDVVTVLKKMKTELFKTEISTSYTYMLSDNMYVANASGVLSTYFKLYNMFYRNHITFGQSRMFIPHITLSFSNKQTVRIESTRLKINSIYLRKIKGETVFDMSE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: I166_CONTE
Sequence: MKLTCVMIVAVLFLTAWTLVMADDSNNGLANLFSKLRDEMEDPEGSKLEKKDCQEKWDYCPVPFLGSRYCCDGFICPSFFCA
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Conotoxin Tx6.6.
What is the protein family that this protein belongs to?
Belongs to the O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FYV10_CANAL
Sequence: MTEPTLNFHIQTHQNQFKIPHELIKKNFKLIQKLIEKQRKQLIDDISKIKKCKTTSPSFKLELIQKLIKNFESFMKKLQNFINKDEEFRSRLIARLENLTELQQYVITNNDNQEGQNHEESTENNNNNRNNNNNSTTTDDDKLLDFHNPNLINWYRDQTNLLIVDYLIKSNTRTRFEDNGEDNPGNIGLLLLKNLTKTNPKLLKLIDYDLLENFNKVFVSIINNHDLSLIVGWFNENKNLLNKINSNLEFEINYCKFLTLIEKGDINEAINYSRENLSGYGNKENYQQTNNNNNNTFSNGDTTSTNHLTNLERLKGLGGLLVFRSMENNNKNNNDLNSNDTPLSSKLMLNSTPFKEYQKLLSNERWESLAQCFIENFTKLYGISKNFPIYIYLSAGLSSLKTKSCYHNVENTIFKHSTGNGIDYDNGNDDYDDDDDDDDEGGVIDSNLSFISAETTTNTNTTSNSGKSLLNDPKYRGPNHYYKLLNKINNCPICSPELFKLSQNLPYAQLITSIFNNPFKLPNGNIYPFDKLLAPTDKYLSEKNTLLRANKVKDPLTREIFTIDSCIRVFPA
What is the function of this protein?
Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase.
What are the official names of this protein?
Protein FYV10.
What is the protein family that this protein belongs to?
Belongs to the FYV10 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: AGN8_PAEDI
Sequence: MAKDPTFEEVTGCQRALFEWADSYDTKDWERLKKCVAPTLRIDYRSFLDKLWEAMPSDEFILMASDPRFLGNPLLKTQHFVGLSTWQKISPDEIEGTHQLRVPHQRYTDSNMKEVAVKGHAHGIATMWYKRVEDEWKFAGVCPQIRWAEFDYDKVFAEGKDHFGENGGNGEHAV
What is the function of this protein?
Dehydratase; part of the gene cluster that mediates the biosynthesis of agnestins, dihydroxy-xanthone metabolites (PubMed:30746079).  The pathway begins with the assembly and cyclization of atrochrysone thioester by the non-reducing polyketide synthase Agnpks1 (PubMed:30746079).  The atrochrysone carboxyl ACP thioesterase AgnL7 then breaks the thioester bond and releases the atrochrysone carboxylic acid as the first enzyme-free intermediate (PubMed:30746079).  The decarboxylase AgnL1 then catalyzes the concerted decarboxylation-elimination required to convert atochrysone carboxylic acid into emodin anthrone, which is further oxidized to emodin by the anthrone oxygenase AgnL2 (PubMed:30746079).  Emodin then undergoes reduction catalyzed by the oxidoreductase AgnL4 to yield the dihydroquinone tautomer which is the substrate for reduction by the short chain dehydrogenase AgnL6 reduction to produce hydroxyketone, followed by AgnL8 dehydration and likely spontaneous autoxidation to chrysophanol (PubMed:30746079).  Baeyer-Villiger oxidation by the oxidase AgnL3 leads to monodictyphenone via cleavage of the C-10/C-10a bond of chrysophanol (PubMed:30746079).  Alternative cleavage at the C-4a/C-10 bond of chrysophanol leads also to the formation some cephalone F (PubMed:30746079).  Further conversion to agnestins A and B, requires reduction to dihydro-monodictyphenone, oxidation to agnestin C probably via an epoxide, and rearrangement to either agnestin A or agnestin B directly, although agnestin A or agnestin B can also interconvert (PubMed:30746079).  Within the cluster, AgnR1 is the only unassigned oxidoreductase present which could be involved in this conversion.  However, AgnR1 seems not to be involved in this step, and thus genes involved in the proposed oxidation/reduction may be located elsewhere on the genome (PubMed:30746079).  Further agnestin A derivatives are probably formed by spontaneous decarboxylations, dehydrations and methanolysis reactions (PubMed:30746079).
What are the official names of this protein?
Dehydratase AgnL8, Agnestins biosynthesis cluster protein L8.
What is the protein family that this protein belongs to?
Belongs to the scytalone dehydratase family.
Protein: PRP45_DEBHA
Sequence: MFSSLLPKPKYSSHEPTSRIKLKKVRAHEKSNQLVKLPENKSDIKVTHNPSNSESTISQLHLNPDGTLNYNLTIASSNSNSRKVQSSYEDTIPLKVKFPNLKHHFPRYTVETCPDDSLKECVEDTKAAINKMINEKMGVDEKTNNKKDDVTYIKYTSNNLVNDPEGSDDERGRERIIQIRNYQEDPMLPPKFKLRKNRHKNPSPPPPLLKSSNNEQTSKLTKEDQAKWQIPSAISNWKNNQGFTISLDKRMVAANGGSELATNDVNLEKFGELSQALENADKQAREEIKIRSEMLKQLAIKEQHEKENKLKELADIARSKKLNNKRPPNGDYDDVKKKTKY
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-processing protein 45.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PANC_BRUSU
Sequence: MQIIHTIEELRQALAPARQQGKKIGFVPTMGYLHKGHLELVRRARVENDVTLVSIFVNPLQFGANEDLGRYPRDLERDAGLLHDAQVDYLFAPTVSDMYPRPMQTVVDVPPLGNQMEGEARPGHFAGVATVVSKLFNIVGPDAAYFGEKDFQQLVIIRRMVDDMAIPVRIVGVETVREDDGLACSSRNVYLTPEQRRAAIIVPQALDEADRLYRSGMDDPDALEAAIRTFISRQPLAVPEVIAIRDPETLERLPALQGRPILVALFVRVGATRLLDNRVIGHAAPQITQERAA
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: I36RA_HUMAN
Sequence: MVLSGALCFRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASLSPVILGVQGGSQCLSCGVGQEPTLTLEPVNIMELYLGAKESKSFTFYRRDMGLTSSFESAAYPGWFLCTVPEADQPVRLTQLPENGGWNAPITDFYFQQCD
What is the function of this protein?
Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling.  Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor.  Proposed to play a role in skin inflammation.  May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus.  May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
What are the official names of this protein?
Interleukin-36 receptor antagonist protein, IL-36Ra, FIL1 delta, IL-1-related protein 3, IL-1RP3, Interleukin-1 HY1, IL-1HY1, Interleukin-1 delta, IL-1 delta, Interleukin-1 family member 5, IL-1F5, Interleukin-1 receptor antagonist homolog 1, IL-1ra homolog 1, Interleukin-1-like protein 1, IL-1L1.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: RS4_LISMC
Sequence: MARYTGPSWKVSRRLGISLSGTGKELERRPYAPGQHGPTQRKKISEYGLQQAEKQKLRHMYGLTERQFKNTFNKAGKLQGKHGENFMILLEQRLDNIVYRLGLARTRRAARQLVNHGHITVDGKRVDIPSYQVSVGQVISVREKSAKNSAIAESLEVSSFVPEYVTFDAETLTGSLNRLPERSELAAEINEAFIVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RK23_SOLBU
Sequence: MDGIKYAVFTDKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKSRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS12_SYNS9
Sequence: MPTIQQLIRTERSRLKVKTKSPALKSCPERRGVCTRVYTSTPKKPNSALRKVARVRLTSGFEVTAYIGGIGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGTLDTSGVKDRRQSRSKYGAKAPKE
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: EX7L_XANC8
Sequence: MADRTEQILTPSQLNTLARDLLEGSFPLVWVEAELGNVTRPASGHLYFTLKDARAQIRCAMFKPKSTWLKFQPREGLRVLARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFEELRARLAAEGVFDAERKQPLPAHVRRLAVITSPSGAAVRDVLSVLARRFPLLEVDILPSLVQGDSAAAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAHTPVVSAVGHETDVSLSDFAADVRAPTPSVAAELLVPDQRELVARVRRAQARLSQLQQHTLGQAMQHADRLALRLRARSPQARLQLLQRRQEDAARHLRARMQHILERLQARVQRAQAGVQSHSPQRHLAPLQQRLRAAHPQAAMQRRLQQDHLHLRGLVRSLEAVSPLATVARGYAIVTRQADGSVVRSAAELTQGDRLRAQLADGSVTVVVDTSETG
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INH_DICCH
Sequence: MKQLIIATLLSALSGGCMASSLRLPSAAELSGQWVLSGAEQHCDIRLNTDVLDGTTWKLAGDTACLQKLLPEAPVGWRPTPDGLTLTQADGSAVAFFSRNRDRYEHKLVDGSVRTLKKKA
What is the function of this protein?
Inhibitor of the extracellular proteases A, B, and C of E. chrysanthemi and the S. marcescens 50 kDa extracellular protease.  It forms a non-covalent bond with the proteases and may prevent autocatalytic cleavage of the proteases zymogen in the periplasm.
What are the official names of this protein?
Proteinase inhibitor.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I38 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: METK_PROMS
Sequence: MSDFIFTSESVTEGHPDKICDQISDAVLDALLTEDPESRVACETVVNTGLCLLTGEITSKAKVDYIKLVRNVIKEIGYEGYRAGGFDANSCAVLVALDEQSPDISQGVNEADDVNDDLEDNTGAGDQGIMFGYACDETPELMPLPISLAHRLAIQLSKVRHENMLNYLLPDGKTQVSIDYKNGVPLSINTILISTQHNPEIDGITNEEEIRQRIKEDLWKNVVLPATEDLEIKPNIQTTRFLVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKSIVKAKLAKKAEVQLSYAIGVAKPISILVETFDTGVISQANLTELINKYFDLRPAAIIKEFDLRNLPQKMGGTFFRKTASYGHFGRRDLDLPWEKVEEKAAQLAEASKVFL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.