PharMolix/UniProtQA huggingface dataset:
Protein: F16PC_STRU0
Sequence: MSQYFSLLKEKFPTKSSLLTEMINLDAICHLPKGTEYFLSDLHGEYQAFDYLLRNASGSIKKKLQECFPEKDSEDIDKLCQYIYYPSEKIAAQQEILGEKALQEELSFYLPDLIQFVKYTGSKYTRSKVRKMLPADYAYIMEELLTEEQPDKNKHFYYQAILAKVIELEQLDNLFVAFAQLIQKLSIDHLHIVGDIFDRGKYPDFILERLRSFRNIDIQWGNHDITWIGAISGSYICMINVIRIAARYNSIDLIEDRYGINLRRLIEYSQSHFQEEDVFNPILDGEEIADSERMVLNQLQQATALLQFKLEHQLIKRRPCFGMEAGLLFSKIDTENQTITIGDITYPLQSFPFEMMDWDNPDGLTEEEEALLKGLMYRFQNSTLLKEHVDFLIEKGGMYHISNNHLLFHGCMPMHSNGDFKSMVFGKQAYSGRALLDFFEEQVLESYKNPDSHEDFQTDIFWYLWCGEVSSLFGKDRMTTFERYYIADKTSHVEHKNPYYKLRENEEICLRILEEFGLDKSAHIVNGHTPVKEKGGELPIKANGRMIIIDGGLAKGYQKTTGIAGYTLISNSYGLELVAHKPFSSVQDVLEGKCDIIFIKRLVEIVENRTLVKETDNGQLLLKEIADLEYLYHHFDQF
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: MENG_BACHK
Sequence: MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALAGAVGEQGKVVGLDFSENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMIGFRQGYILYFKYIMPLFGKLFAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: BIOD_CLOAB
Sequence: MRGIYLVGTDTEIGKTVISAALVYILCKAGYKTAYFKAALSDAEELNGKLIPGDTEFVCSLSGIQEDYEKLTPYIYKTAVSPYLASKIENKPIDIQVIKDKLTKLENEYGYVLCEGSGGVICPITDVDNKIYTLGNLIKDMKMDVILVCRAGLGTINHTVLTVSYLKNNGIEVKGIIVNQYEENRLCKDNINMIKKMTGIPILGVMPYINENKKNFIEELKYNACNIFKADEIAGLMKEV
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_META3
Sequence: MIIIEKTEQIKGTINAPPSKSYTHRAVICASLADGTSEIISPLNSADCLSSVHGAMMLGAEIDATDKNKWVVVGNNNSPKTPNNVVDIGNSGTTLRILTGIASQIPEGYAILTGDSSIITRPMQPLLDALNQLGIRAFSSKTDGTAPIIVEHGEIKNNVVKIRGDMSSQFITSLMMTMPFSKMDSTIELTTPLKSAPYLDITIDVLDKFGVKIEKVKNKNKLTKFIIKGNQKYKPYSYTVEGDCSSASYFIAAGVLMNSDITINNIFKNSKQGDREIVNIVKKMGAPIIEEEDKIIIKGPYKLKGIDIDVKDTPDLVPTIAILGCFAEGTTTIYNGEHVRLKECDRLMACAKELTKMGAKITEKPDGLIIEGVGKLNGAEMETYHDHRLVMAFTVAGMMAEGKTIIKGEDAVKISFPNFVEAIKSIGANITIK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATK_CRUWA
Sequence: MEKLQGYFEFNGARQQSFLYPLFFREYIYVLAYDHGLNRLNRTRSIFLENTDYDKKYSSLIVKRLILRMYEQNRLIIPTKDLNQNPFLGHTSLFYYQMISVLFAVIVEIPFSLRLGSSFQGKQLKKSYNLQSIHSIFPFLEDKLAHFNYVLDVLIPYPIHLEILVQTLRYRVKDASSLHFFRFCLYEYCNWKNFYIKKKSILNPRFFLFLYNSHVCEYESIFFFLRKRSSHLRSTSYAVLFERILFYGKIQHFLKVFVNNFPAILRLLKDPFIHYVRYHGRCILATKDTPLLINKWKYFFVNLWQCYFSVWFQSHKVNINQLSKDNLEFLGYLSSLRLNPLVVRSQMLENSFLIDNVRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKATWTDSSDSDILNRFVRICRNISHYYSGSSKKKNLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQVLSLIFPRSYYASKRLYRVRIWYLDILYLNDLVNHE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COLI1_CYPCA
Sequence: MVRGERMLCPAWLLALAVLCAAGSEVRAQCMEDARCRDLTTDENILDCIQLCRSDLTDETPVYPGESHLQPPSELEQTEVLVPLSPAALAPAEQMDPESSPQHEHKRSYSMEHFRWGKPVGRKRRPIKVYTNGVEEESTETLPAEMRRELATNEIDYPQEEGALNQQDKKDGSYKMSHFRWSSPPASKRYGGFMKSWDERSQKPLLTLFKNVINKEHQKKDQ
What is the function of this protein?
Endogenous opiate.
What are the official names of this protein?
Pro-opiomelanocortin-1, POMC-1, Corticotropin-lipotropin 1, Corticotropin-lipotropin I, Pro-opiomelanocortin I, POMC I.
What is the protein family that this protein belongs to?
Belongs to the POMC family.
What are the subcellular locations of this protein?
Secreted. Note=Melanocyte-stimulating hormone alpha and beta-endorphin are stored in separate granules in hypothalamic POMC neurons, suggesting that secretion may be under the control of different regulatory mechanisms.
Protein: QUEC_BRUSI
Sequence: MKTLVICSGGLDSVSLAHKMAAEHELTGLLSFDYGQRHKKELDFAQACAKRLGVPHQIIDIRTIGASLTGSALTDDVDVPDGHYAEETMKVTVVPNRNAIMLAIAFGVAAAQKADAVALAVHGGDHFIYPDCRPGFIEAFQTMQKHALDGYADVKLLAPYVHATKADIVADGAKYRTPFEATWSCYKGADRHCGRCGTCVERREAFHLAGIDDPTSYEDADFWRATTQKRNA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: ISPF_XANOR
Sequence: MSFNFRIGQGYDVHAFGPGEHVMLGGVRVAHSHGVLAHSDGDVVLHALCDAMLGALALGDIGRHFPPSDERWKDADSAQFLQHCDGLLRERGWRVGNADITVICERPKVGPHAVAMRERIAGLLAIELDAVSVKATTSEQLGFTGRGEGIAAQAAVLLGRIAA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PDEK_ECOLI
Sequence: MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAKELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHAITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPGDSSMIAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK
What is the function of this protein?
Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG.
What are the official names of this protein?
Probable cyclic di-GMP phosphodiesterase PdeK.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHOL_MYCLE
Sequence: MTHHETSAVDASSASMHVRSTIDVPPDLVVGLLGSADENLRALERMLSADLHVRGNTVAFSGEPADVALAERAISELVAIVASGHPLTPEVVRHGVAMLVGTGNESPAEVLTLDILLRRGKTVRPKTLNQKRYVDAIDANTIVFGIGPAGTGKTYLAMAKAVNALQTKQVTRIILTRPAVEAGERLGFLPGTLSEKIDPYLRPLYDALYDMMDPELIPKLMSSGVIEVASLAYMRGRTLNDAFIVLDEAQNTTAEQMKMFLTRLGFGSKVVVTGDVTQIDLPGGARSGLRAAVDILEHIDDIYVAELASVDVVRHRLVSEIVDAYAEYEEHDLGMNRAARRASGARNRR
What are the official names of this protein?
PhoH-like protein.
What is the protein family that this protein belongs to?
Belongs to the PhoH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ANI1_EMEND
Sequence: MRILKSHPLLKIVNSYIIDSPQPANLSYLWNFGSLLALCLGIQIVTGVTLAMHYTPSVSEAFNSVEHIMRDVNNGWLVRYLHSNTASAFFFLVYLHIGRGLYYGSYKTPRTLTWAIGTVILIVMMATAFLGYVLPYGQMSLWGATVITNLMSAIPWIGQDIVEFIWGGLYTDEPQCGDVLLKILLNAGKSPILGFAYDLFFIIVLLIGVKIAMTRGKSAGVRSLHTSEASQRLHAGDLTYAYLVGLFEGDGYFSITKKGKYLTYELGIELSIKDVQLIYKIKKILGIGIVSFRKINEIEMVALRIRDKNHLKSFILPIFEKYPMFSNKQYDYLRFRNALLSGIISLEDLPDYTRSDEPLNSIESIINTSYFSAWLVGFIEAEGCFSVYKLNKDDDYLIASFDIAQRDGDILISAIRKYLSFTTKVYLDKTNCSKLKVTSVRSVENIIKFLQNAPVKLLGNKKLQYLLWLKQLRKISRYSEKIKIPSNY
What is the function of this protein?
Mitochondrial DNA endonuclease and mRNA maturase involved in intron homing and required for splicing of the cytochrome b (cobA) gene intron, containing its own coding sequence.  The protein stimulates the intrinsic ribozyme activity of the intron through binding to and stabilizing specific secondary and tertiary structure elements in the RNA.  As an endonuclease it introduces a specific double-strand break at the junction of the two exons the cobA gene and thus mediates the insertion of an intron, containing its own coding sequence (group I intron), into an intronless gene.  Recognizes with limited specificity and cleaves the sequence 5'-GAGGAGGTTTCTCTGTA-3'.  The proteins RNA and DNA recognition and binding surfaces are independent.
What are the official names of this protein?
Intron-encoded DNA endonuclease I-AniI, COB intron protein, mRNA maturase bI1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the LAGLIDADG endonuclease family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PTGA_STAES
Sequence: MFKKLFGKAKEVDKNIKIYAPLTGEYVKIEDIPDPVFAQKMMGEGFGINPTEGEVVSPIEGKVDNVFPTKHAVGLKAENGLELLVHIGLDTVQLDGKGFEVLVESGDDIKIGDPLIRFDLEYINNNAKSIISPIIITNSDQTESIHIEDVQAVVKGETQVIDVTVS
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIIA component, EIIA-Glc, EIII-Glc, Glucose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPC6B_HUMAN
Sequence: MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL
What is the function of this protein?
Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (PubMed:16025134, PubMed:16828797).  Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (Probable).
What are the official names of this protein?
Trafficking protein particle complex subunit 6B, TRAPP complex subunit 6B.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network. Endoplasmic reticulum.
Protein: SYT_DELAS
Sequence: MIHITLPDGSQREYPGPVTVAEVAASIGTGLAKAALAGKVGTGDDAKVVDTSFVINKDMPLSIVTAKDADGLDVIRHSTAHLLAYAVKDLFPDAQVTIGPVIENGFYYDFSYKRPFTPEDLVAIEKRMAELAAKDEPVVRRVLPRDEAVAYFKGIGENYKAEIIASIPSNEDVSLYREGSFEDLCRGPHVPSTGKLKFFKLMKVAGAYWRGDHRNEMLQRVYGTAWASKDDLQQYLHMLEEAEKRDHRKLGRELDLFHIDEHSPGTVFWHPKGWSLWQEVEQYMRRVYRDNGYQEVKGPQILDKTLWEKTGHWDKYRENMFTTESEKRDYALKPMNCPGHILIFKQGIKSYRDLPLRYGEFGQCHRNEPTGGLHGIMRVRGFTQDDGHVFCTEDQIQPEVLAFTTLLQKVYADFGFSDIIYKVATRPEARIGSDESWDKAEAALINSLEASGCEYVISPGDGAFYGPKIEYTLKDAIGRQWQCGTIQVDFSMPERLDAEYVGEDGDRHRPVMLHRAIVGSLERFIGILIEQHAGAMPTWLAPVQAAVLNITDAQADYVREVAQKLQKAFPNQGLRVATDLRNEKITYKIREHSLQKLPYILVAGDKEKAAGAVAVRARGNKDLGVMSVDAFIELVAKDIAAKA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBM_AMBTC
Sequence: MEVNILAFIATALFILVPTAFLLIIYVKTVSQSVE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PBP5_PSEAE
Sequence: MRNRLLSLVTLFLSLSVATAVSASPPPKAGLPLQQELASGSALVTDQNTGKVLYSRNPDLVVPIASITKLMTAMVVLDSKLPLDEVLPIAISETSEMRGVFSRVRVGSQISRRDMLLLALMSSENRAAASLAQNYPGGKNAFVKAMNAKAHALGMKNTRYVEPTGLSLHNVSTARDLTRLLVASRQYPLLSQWSTTPEKTVAFRHPNYTLGFRNTNHLINNKTWNIQLTKTGFTNEAGHCLVMRTTINRSPVNLVVLDAFGKYTHFADATRLRRWLETGQVTAIPAAAKAYRLQRDRERGLGQPVAQAVR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanyl-D-alanine endopeptidase, DD-endopeptidase, Penicillin-binding protein 5, PBP-5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S11 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LACD2_STRP8
Sequence: MTITLTENKRKSMEKLSVDGVISALAFDQRGALKRMMAQHQTKEPTVEQIEELKSLVSEELTPFASSILLDPEYGLPASRVRSEEAGLLLAYEKTGYDATTTSRLPDCLDVWSAKRIKEAGAEAVKFLLYYDIDGDQDVNEQKKAYIERIGSECRAEDIPFYLEILTYDEKIADNASPEFAKVKAHKVNEAMKVFSKERFGVDVLKVEVPVNMKFVEGFADGEVLFTKEEAAQAFRDQEASTDLPYIYLSAGVSAKLFQDTLVFAAESGAKFNGVLCGRATWAGSVKVYIEEGPQAAREWLRTEGFKNIDELNKVLDKTASPWTEKM
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase 2, D-tagatose-1,6-bisphosphate aldolase 2, Tagatose-bisphosphate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: UPP_MYCTU
Sequence: MQVHVVDHPLAAARLTTLRDERTDNAGFRAALRELTLLLIYEATRDAPCEPVPIRTPLAETVGSRLTKPPLLVPVLRAGLGMVDEAHAALPEAHVGFVGVARDEQTHQPVPYLDSLPDDLTDVPVMVLDPMVATGGSMTHTLGLLISRGAADITVLCVVAAPEGIAALQKAAPNVRLFTAAIDEGLNEVAYIVPGLGDAGDRQFGPR
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: ZHX1_MOUSE
Sequence: MASRRKSTTPCMVLASEQDPDLELISDLDEGPPILTPVENAKAESVSSDEEVHGSVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFVKEENTEQGESIDVSSSGISISKTPIMKMMKNKVENKRITVHHNSAEGTSEEKENGVKASQEENAESVSSSALESNTSTSTINRVHPSPASTVVTPTAVLPGLAQVITAVSAQQNSNLLPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPNQTNVQKSQVPAAQPATDTKPATAAVPSSPSVRPEAALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSATIIIDSSDETPEPPAAAASQQKQSWNPFPDFAPQKFKEKTAEQLRALQASFLNSSVLTDEEVNRLRAQTKLTRREIDAWFTEKNKTKALKDEKIEVDESNVGSSKEEPGESSPGDETVAPKSGGTGKICKKTPEQLHMLKSAFVRTQWPSAEEYDKLAEESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSSNSSSLNGLSSLRRRGRGRPKGRGRGRPRGRPRGGKRMNTWDRVPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNRSHMGYEQVREWFAERQRRSELGIELFEENEEEDEVVDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD
What is the function of this protein?
Acts as a transcriptional repressor.  Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA.  May link molecule between DNMT3B and other co-repressor proteins (By similarity).
What are the official names of this protein?
Zinc fingers and homeoboxes protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZHX family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalized in the nucleus with DNMT3B.
Protein: RS9_MAGMM
Sequence: MAQETFNATGKRKESVARVRIVPGSGKVTINQKPMDVYFGRPVLRMVVNQPFSVTEMENKFDVLVNVHGGGVSGQAGAIKHGISKALVDYDEALRPALKKAGFLTRDARTVERKKYGRHKARKSTQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: HIS4_BLOFL
Sequence: MIIPALDIINGDAVRLYQGKYQSQSHYGNPYSILSTYVQQGATMIHLVDLDGARNPKNRQLSLIKELTHTAITSHLKIQIGGGIRHATDIKTLLKFGVNRVILGSIAITHPKKVKQWFTYFNPSSLVLALDIYIDSKNNRKVVIHGWQKETNIQLEEVIENYNSVGLKHVLCTDISKDGTLLGSNINLYQSICYKWPKISFQASGGVAKLTEILQLRSSGVNSIIIGRSFLEKKFTLTEAISCWQNASSRV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAR3_HAECO
Sequence: KSAYMRF
What is the function of this protein?
Active on neuromusculature.
What are the official names of this protein?
FMRFamide-like neuropeptide PF3, KSAYMRF-amide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_DICNV
Sequence: MNEEQKKALTAVLTQLDKQFGKGTVMRLGEQVAAHDIQAISTGSLTLDIALGIGGLPKGRIVEIYGPESSGKTTMMLHVIAEAQKNGGTAAFIDAEHALDPIYARKLGVNTDDLYVTQPDTGEQALEICDALVRSGAFDVIVVDSVAALTPKAEIEGEMGDSHVGLQARLMSQALRKLTGNIKRANTLVVFINQIRMKIGVMFGSPETTTGGNALKFYASVRMDIRRIGSIKEGDEVLGNETRVKVVKNKVAPPFKQAEFDILYGQGVSREGEIIQLAVNADIMQKSGAWYSYRDEKIGQGKEKVRLYLKEHPDVAQEIETKIREKFIGGELHLPDAAGDEIDTSINDEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y835_ARCFU
Sequence: MEKRRAEIAAAIITAPTILAMMSTVLRALIFSSCIKNFLIFSMLKHSSYCLAILVYQKNRKAVMWGSDLFYHLRGFSSIFEQKTYIYESILSLQRKNRVRFKLPRII
What are the official names of this protein?
Uncharacterized protein AF_0835.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: VIF_SIVVG
Sequence: MNQEKEWVMRVTWKVPEELITKWQGIVRYWMRTRKLDWKYRMHYQITWAWYTMSRYEIPLGQHGSIHVDLYWHLTPEKGWLSTYAEGIQYLSNRDPWYRTELDPATADSLIHTHYFTCFTERAIRKALLGQRFTFCQFPEGHKKTGQVPSLQYLALLAHQNGLRQRSQRSKTGGTRNMGFEQGAVGRMAKRHARRYQSGSQDAFWARAPVPSMELLSGGGRKESHSHARKGL
What is the function of this protein?
Counteracts the innate antiviral activity of APOBEC3G.  Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions.  Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery.  Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1.  Binds viral RNA and affects the stability of viral nucleoprotein core.  May play a role in viral morphology (By similarity).
What are the official names of this protein?
Virion infectivity factor, Vif, Q protein, SOR protein.
What is the protein family that this protein belongs to?
Belongs to the primate lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Virion. Note=Seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor (By similarity).
Protein: 18K1_MYCAV
Sequence: MLMRSDPFRELDRLTNQVLGTPTRPAVMPMDAWRVGRRLVVEFDLPGIDAESLDIDIERNVLTVRAERPALDPNREMLATERPRGVFSRELVLGDNLDTDKIEASYRDGVLSLHIPVDEKARPRKIAVGAARHPEPSPKTAREVVNA
What is the function of this protein?
Not known.  This protein is one of the major immune reactive proteins in mycobacteria.
What are the official names of this protein?
18 kDa antigen 1, Clone MAVC124.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: RL20_SALPK
Sequence: MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TDIF1_RAT
Sequence: MGATGDTGGPRPGTESRRPGNVGNAGAAGQPVLTNPWNIMIKPRQVQRRGRRSQMTTSFTDPAISMDLLRAVLQPSINEEIQSVFNKYMKFFQKAALNVRDNVGEEVDAEQLIQEACRSCVEQAKLLFSDGEKVIPRLAHELPGIKRGRQAEEESHREAPFPKRGKVGLPGHVLSNDRAAAGMVWKPKSCEPIRREGPKWDPARLNESTTFVLGSRANKALGMGGTRGRIYIKHPHLFKYAADPQDKHWLAEQHHMRATGGKMAYLLIEEDIRDLAASDDYRGCLDLKLEELKSFVLPSWMVEKMRKYMETLRTENEHRAAEATPQT
What is the function of this protein?
Increases DNTT terminal deoxynucleotidyltransferase activity (in vitro).  Also acts as a transcriptional regulator, binding to the consensus sequence 5'-GNTGCATG-3' following an AT-tract.  Associates with RAB20 promoter and positively regulates its transcription.  Binds DNA and nucleosomes; may recruit HDAC1 complexes to nucleosomes or naked DNA.
What are the official names of this protein?
Deoxynucleotidyltransferase terminal-interacting protein 1, Terminal deoxynucleotidyltransferase-interacting factor 1, TdIF1, TdT-interacting factor 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSCL_STAAC
Sequence: MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIGKIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEAVVEENVVLLTEIRDLLREKK
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LYTN_STAAC
Sequence: MFLYYCKECFIMNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKSKDFTRGYEQNVFAKSELNANKNTTKDKIKNEGAVKTSDTSLKLDNKSAISNGNEINQDIKISNTPKNSSQGNNLVINNNELTKEIKIANLEAQNSNQKKTNKVTNNYFGYYSFREAPKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKPKTVSSNNKSNSNSSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGAKDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKFQSLDQNWNNGGWRKAEVAHKVVHNYENDMIFIRPFKKA
What is the function of this protein?
Probably involved in peptidoglycan hydrolysis.
What are the official names of this protein?
Probable cell wall hydrolase LytN.
What are the subcellular locations of this protein?
Secreted.