PharMolix/UniProtQA huggingface dataset:
Protein: YHBQ_ECOUT
Sequence: MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAVFAELLSSLQTPEIKSD
What are the official names of this protein?
UPF0213 protein YhbQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0213 family.
Protein: YCF21_NEOYE
Sequence: MTFNFISFCRIEVILPCQIYSNTSIPLIWKIVLLGDGSFTRHCQIITYRDTEINHISTSIYSKVHNSPQFYVNRRVWIGNNLKNKLIFASSWWNIESYQAIYKYPSRAIGSLFIQSDLDYYRDIHCLFLGYSTELENLFLVPGPFWGRYYTLFYKGKPISLIYEIFSPLLENFQ
What are the official names of this protein?
Uncharacterized protein ycf21.
What is the protein family that this protein belongs to?
Belongs to the ycf21 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YAAA_SALEP
Sequence: MLILISPAKTLDYQSPLATTRYTQPELLDHSQQLIQQARQLSAPQISRLMGISDKLADLNATRFHDWQPHFTPDNARQAILAFKGDVYTGLQAETFNDADFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDIITDKLNEALEAQGDRVVVNLASEEYFKSVKPKKLNAELIKPVFLDEKNGKFKVVSFYAKKARGLMSRFIIENRLTKPEQLTAFDREGYFFDEETSTQDELVFKRYEQ
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: DID4_SCHPO
Sequence: MGLTSWLFGGGKSPQEQLRAHQRSLGRAERELDRERTKLDQRERALIQEIKGSAKAGNTGAARIQARDLMRLRNSRKKMMNAKTQLQAISLRLQTMRTSEQMMQSMRGATRLLTGMNKSMNIPAMARITQQFERENEIMEQRQEMIDENMDDALEEDDEEEADELVNKVLDEIGVDLSQGLPDAATQIGTVPELKTEDNLQARLDELAKR
What is the function of this protein?
Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB).  Acts a component of the ESCRT-III complex, which appears to be critical for late steps in MVB sorting, such as membrane invagination and final cargo sorting and recruitment of late-acting components of the sorting machinery.  The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complex assemblies (By similarity).
What are the official names of this protein?
ESCRT-III complex subunit did4, Vacuolar protein-sorting-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane; Peripheral membrane protein.
Protein: KTHY_VIBVU
Sequence: MKQAKFIVIEGLEGAGKSTAIQTVLDTLRQAGINEIAQTREPGGTPLAEKMRALVKEEHPGEHLHDMTELLLLYAARVQLVENVIKPALHEGKWVVGDRHDLSSQAYQGGGRQIDATLMKNLRDTALGEFKPAFTLYMDIDPKVGLERARGRGELDRIEKMDISFFERTRQRYLELAKSDASIVTINAEQSIEQVANDIRSALNLWLEQLQD
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: KDGK_THET8
Sequence: MLEVVTAGEPLVALVPQEPGHLRGKRLLEVYVGGAEVNVAVALARLGVKVGFVGRVGEDELGAMVEERLRAEGVDLTHFRRAPGFTGLYLREYLPLGQGRVFYYRKGSAGSALAPGAFDPDYLEGVRFLHLSGITPALSPEARAFSLWAMEEAKRRGVRVSLDVNYRQTLWSPEEARGFLERALPGVDLLFLSEEEAELLFGRVEEALRALSAPEVVLKRGAKGAWAFVDGRRVEGSAFAVEAVDPVGAGDAFAAGYLAGAVWGLPVEERLRLANLLGASVAASRGDHEGAPYREDLEVLLKATQTFMR
What is the function of this protein?
Involved in the degradation of glucose via the semi-phosphorylative Entner-Doudoroff pathway.  Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG).
What are the official names of this protein?
2-dehydro-3-deoxygluconokinase, 2-keto-3-deoxygluconokinase, 3-deoxy-2-oxo-D-gluconate kinase, KDG kinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase pfkB family.
Protein: PPNP_JANMA
Sequence: MSTQFDQVSVIKKANIYFDGKCVSHSVLFADGTKKTIGVIFPSTLKFNTGAAEIMELNAGKCRIRLAGATDWETYEGGQQFNVPANSSFDIETIDTLDYVCHFV
What is the function of this protein?
Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases.  Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates.  Also catalyzes the reverse reactions.
What are the official names of this protein?
Pyrimidine/purine nucleoside phosphorylase, Adenosine phosphorylase, Cytidine phosphorylase, Guanosine phosphorylase, Inosine phosphorylase, Thymidine phosphorylase, Uridine phosphorylase, Xanthosine phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the nucleoside phosphorylase PpnP family.
Protein: DABA_NATPD
Sequence: MTSESPTNYDGIDSRIDTVADRVGSVWPLHSFVTANPLSGFEGSPFEDAVAEGERLFGGRGYPRADIFRRAWEDGRIDDDALRTELERRGIERDPETLLEAMETAETKRDDDPDDATAAVDRVLSKWLAAYLDQGQAPWPMPNREEGFYSAWRAVAPYDSDVPGCDDTEDVPATATGAVETVLDAYPRRRWDSIIEHHLAALPGWTGFIKQRADDEFDPWQSEYPITLTEYLGVRLTLVDLLDAPVAPETDADAGDETTAVREAWLSAWEQSYREHLLEDVDDDVTESSHGNGKRPAAQLVFCIDTRSEIIRRHIEQQGPYETHGYAGFFGVPMRHEAYGSDVTTEACPPIVEPEHIIADRPDAHHAEQETAHNRWHGLVSAARKHFKRLKTNPVAAFPFVEGAGSAYGSAMALRTLLPSAVYKLGSTVDEHVPSSHEFCSPTLDRPRMTHEEKVEYAQTAFELMGWTEFARLVVFTGHTSHTTNNPFDSSLQCGACAGNPGGPNARVLAKICNDEAVKDDLRERGVDIPDDTVFVGAEHNTTTDEITLFDGEVPKSHHADVAALRDSLEQARAGAAAERSEALNGADPDKGVSETASRAADWAQTRPEWGLAGNASFVIGPRELTADSDLDGRAFLHSYDWTTDPDGDALELIMLGPLVVTQWINNQYYFATVDNRVYGSGSKVTQNPVGNIGVVQGNGGDLMMGLPLQSLMSDDDSPYHQPLRLTAVIHASVENVTDILREHGHVRRLVDNGWVGNLTVVDPTRDNAAFDYVGGLEWEPSVQQDASSERVAAPAASD
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RPOZ_FRATT
Sequence: MARVTVEDCLDKVETRFDLVVLASMRANKILKNGYSESMENEKKEKATVVALREIAESEITPEQILRNEIEG
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: MURC_SHEON
Sequence: MTKTERYLQLRSMIPEMRRIKRIHFVGIGGAGMGGIAEVLVNEGYVVSGSDIAQNAVTDRLCLLGAKIHIGHGADNVQQADVVVVSTAINPQNPEIIAAKELRIPIVRRAEMLAELMRYRHGVAIAGTHGKTTTTSLIASLYGQAGRDPTFVIGGLLNSAGTNARLGTSRYLIAEADESDASFLHLQPMVSVVTNIEADHMDTYGGDFEKLKSTFVDFLHNLPFYGVAVVCIDDPVVREIMPRISRHIVTYGFRDDADVQALNFSQQGHQCRFTVRRKGKEDLDLLLNLPGQHNVLNALAAIAVATEDEIDDSAIIQALAEFQGIGRRFQHLGKFATPKGEVMLVDDYGHHPSEVAATIKAARAGWPEKRLVMAYQPHRYTRTRDLYEDFIEVLSQVDCLLLLDVYSAGEAPIPGADGRALCRSIRLRGQLDPIFIASPEQLAEVLPDVLQEGDLLLTQGAGNIGALSRKLAASELGFSTGATTEVKP
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPC2_YEAST
Sequence: MVAATKRRKTHIHKHVKDEAFDDLLKPVYKGKKLTDEINTAQDKWHLLPAFLKVKGLVKQHLDSFNYFVDTDLKKIIKANQLILSDVDPEFYLKYVDIRVGKKSSSSTKDYLTPPHECRLRDMTYSAPIYVDIEYTRGRNIIMHKDVEIGRMPIMLRSNKCILYDADESKMAKLNECPLDPGGYFIVNGTEKVILVQEQLSKNRIIVEADEKKGIVQASVTSSTHERKSKTYVITKNGKIYLKHNSIAEEIPIAIVLKACGILSDLEIMQLVCGNDSSYQDIFAVNLEESSKLDIYTQQQALEYIGAKVKTMRRQKLTILQEGIEAIATTVIAHLTVEALDFREKALYIAMMTRRVVMAMYNPKMIDDRDYVGNKRLELAGQLISLLFEDLFKKFNNDFKLSIDKVLKKPNRAMEYDALLSINVHSNNITSGLNRAISTGNWSLKRFKMERAGVTHVLSRLSYISALGMMTRISSQFEKSRKVSGPRALQPSQFGMLCTADTPEGEACGLVKNLALMTHITTDDEEEPIKKLCYVLGVEDITLIDSASLHLNYGVYLNGTLIGSIRFPTKFVTQFRHLRRTGKVSEFISIYSNSHQMAVHIATDGGRICRPLIIVSDGQSRVKDIHLRKLLDGELDFDDFLKLGLVEYLDVNEENDSYIALYEKDIVPSMTHLEIEPFTILGAVAGLIPYPHHNQSPRNTYQCAMGKQAIGAIAYNQFKRIDTLLYLMTYPQQPMVKTKTIELIDYDKLPAGQNATVAVMSYSGYDIEDALVLNKSSIDRGFGRCETRRKTTTVLKRYANHTQDIIGGMRVDENGDPIWQHQSLGPDGLGEVGMKVQSGQIYINKSVPTNSADAPNPNNVNVQTQYREAPVIYRGPEPSHIDQVMMSVSDNDQALIKVLLRQNRRPELGDKFSSRHGQKGVCGIIVKQEDMPFNDQGIVPDIIMNPHGFPSRMTVGKMIELISGKAGVLNGTLEYGTCFGGSKLEDMSKILVDQGFNYSGKDMLYSGITGECLQAYIFFGPIYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCVIAYGASQLLLERLMISSDAFEVDVCDKCGLMGYSGWCTTCKSAENIIKMTIPYAAKLLFQELLSMNIAPRLRLEDIFQQ
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.  Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit.  Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase III subunit RPC2, RNA polymerase III subunit C2, C128, DNA-directed RNA polymerase III 130 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RIMP_HELPY
Sequence: MTKKIEEKIGGVIESLGYLLYDVSLVKENEQHVLRVSLKNPNGAVSLDICQQVSEIISPLLDVCDFIQDAYILEVSSMGLERTLKTPKHFKLSLGEKVEVKLTNKESFQAVLKDANDLSADFELEDHAIKSVEYKDLKKVKTLFEW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_CHLL3
Sequence: MSQISAKDVKDLRDTTGIGMMDCKKALEETGGDMEKAIEYLRKKGAALAAKRAEKDASEGMICIRVSADRKSGVILELNCETDFVARGEVFTGFAGALGDLALENRTVSTDALLKLRMADAMGGELVDDAIKTMTGKLGEKIDLKRLFFFDAADGLVESYVHPGAQLGAIIHLATDKPEAVAPLAKDLAMQVAAAAPIEVDRSAVPQELIAKESEIYRQQALGQGKKEEFVDKIVLGRLDKYYQEVVLLEQSFIKSNNMKVSAVLDEFRKLLQAAVDVKEFVRYQLGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: A1KA4_LOXSA
Sequence: WIMGHMVNAIAQIDEFVNLGANSIETDVSFDKNANPEYTYHGIPCDCGRTCTKWEYFNTFLGGLRKATTPGDSKYHEKLVLVVFDLKTGSLYDNQAYDAGTKLAKSLLQNYWNKGNKGGRAYIVLSIPNLDHYKLITGFKETLTKEEHPELMDKVGYDFSGNDDIGDVAKAYKKAGVTGHVWQSDGITNCLLRGLDRVRKAVANRDSSNGYINKVYYWTVDKRASTRDALDAGVDGIMTNYPDVIADVLSESAYTAKFRIATYDDNPWETFKN
What is the function of this protein?
Dermonecrotic toxins cleave the phosphodiester linkage between the phosphate and headgroup of certain phospholipids (sphingolipid and lysolipid substrates), forming an alcohol (often choline) and a cyclic phosphate (By similarity).  This toxin acts on sphingomyelin (SM) (By similarity).  It may also act on ceramide phosphoethanolamine (CPE), lysophosphatidylcholine (LPC) and lysophosphatidylethanolamine (LPE), but not on lysophosphatidylserine (LPS), and lysophosphatidylglycerol (LPG) (By similarity).  It acts by transphosphatidylation, releasing exclusively cyclic phosphate products as second products (By similarity).  Induces dermonecrosis, hemolysis, increased vascular permeability, edema, inflammatory response, and platelet aggregation (By similarity).
What are the official names of this protein?
Dermonecrotic toxin LsaSicTox-alphaIB1aiv, Phospholipase D, PLD, Sphingomyelin phosphodiesterase D, SMD, SMase D, Sphingomyelinase D.
What is the protein family that this protein belongs to?
Belongs to the arthropod phospholipase D family. Class II subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: BACS2_HALSA
Sequence: MALTTWFWVGAVGMLAGTVLPIRDCIRHPSHRRYDLVLAGITGLAAIAYTTMGLGITATTVGDRTVYLARYIDWLVTTPLIVLYLAMLARPGHRTSAWLLAADVFVIAAGIAAALTTGVQRWLFFAVGAAGYAALLYGLLGTLPRALGDDPRVRSLFVTLRNITVVLWTLYPVVWLLSPAGIGILQTEMYTIVVVYLDFISKVAFVAFAVLGADAVSRLVAADAAAPATAEPTPDGD
What is the function of this protein?
Photophobic photoreceptor responsible for the negative phototaxis.  Activates the sensory rhodopsin II transducer (HTR-II) in response to blue light (By similarity).
What are the official names of this protein?
Sensory rhodopsin-2, Sensory rhodopsin II, SR-II.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RISB_STRAW
Sequence: MSGKGAPELSVRNCGDLRVAVIAAQWHEKVMDGLVDGALRALHELGIDEPTLLRVPGSFELPVVAKVLAGRGYDAIVALGVVIRGGTPHFDFVCQGVTQGLTQVSVDTGVPVGFGVLTCDTEEQALDRAGIEGSHEDKGHEAVTAAVATAATLRSVSEPWR
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RSD_SALPC
Sequence: MLNQLENLTERVGGSNKLVDRWLDVRKHLLVAYYNLVGIKPGKESYMRLNEKALDNFCQSLVDYLSAGHFSIYERILHKLEGNGQLLHAAKIWPLLEDNTQRIMDYYDTSLETAIDHDNCLEFQQALSDIGEALEARFVLEDKLIMLVFDAMHDGARVKRPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_LEGPH
Sequence: MSPSIVFTGGGTAGHVTPNIALIKEFRKEGWNVEYIGSVSGIEKEMIEPLDIPFHGVSSGKLRRYFSLKNLLDPFKIVLGIIQSSLLFYKIKPDVVFSKGGFVAFPVVVGAWLNRIPVVAHESDMSPGLANRLSFPFVNKICLTFDAGKKYFKRQDKIEVTGTPIRQQLLTGNRMKGLELCGFNSSKPCLLVVGGSLGAGSINSCIRSALKQLTSEFQVIHLCGKGKLDSSLVGVEGYCQFEYANEELADLFAASSVVISRAGANSLYEILALGKPHILIPISSQVSRGDQIQNARYFQGLGISVVIQDELLKADVLLQAVQDVMRKKDEIDNKIKALKIESATDKIVAIIKEQAHVQTPRIV
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CYB_ACRMA
Sequence: MPHQQILMLFGLLPVATNISTWWNFGSMLLTCSALQIMTGFFLSMHYTANINLAFSSIVHVVRDVPHGWMMQNLHAIGASMFFICVYIHVARGLYYGSYLNKETWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGTTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHIMLLHEEGSSNPLGTNSDIDKIPFHPYHTYKDLFMISSMIMIMLLTISFIPDIFNDPENFSEANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALAMSIMILLTVPFTHTANTRSMTFRPFMQLMFWTLVATFMIITWTATKPVEPPYTMISQVTSSLYFMFFMSNPIVGWLENKIMKTQL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS11_CLOB8
Sequence: MAAKTVKKTRRRKERKNVEHGAAHIKSTFNNSIVTLTDAVGNALSWSSAGALGFRGSRKSTPFAAQMAAETAAKVAMEHGLKSIEVYVKGPGSGREAAIRSLQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: AZOR_STRA3
Sequence: MNTLIVNSHPDFSNPYSFTTILQEKFIELYNEHFPNHQLSILNLYDCVLPEITKEVLLSIWSKQRKGLELTADEIVQAKISKDLLEQFKSHHRIVFVSPMHNYNVTARAKTYIDNIFIAGETFKYTENGSVGLMTDDYRLLMLESAGSIYSKGQYSPYEFPVHYLKAIFKDFMAFDDFCVVRAEGTDILDRQVVLDKMNQDLREAFEAFYSKE
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: TXVE_CROAT
Sequence: MAVYLLAVAILFCIQGWPSGTVQGQAMSFMEVYERSVCQTREMLVSILDEYPSEVAHLFRPSCVTVLRCGGCCTDESLTCTATGKRSVGREIMRVDPRKGTSKIEVMQFTEHTECECRPRSTVNNGKRKKNPKEGEPRAKFPLV
What is the function of this protein?
Snake venom VEGFs that may contribute to venom dispersion and prey subjugation by inducing vascular permeability and hypotension.  This protein induces an increase in capillary permeability after intradermal injection, as well as a drastic hypotensive effect after intravenous injection (By similarity).  The hypotension is mediated by nitric oxide (NO), which is produced by VEGF-activated endothelium NO synthase.  Also induces angiogenesis in vitro (By similarity).  Like other crotalid VEGFs, this protein interacts with VEGF receptor-1 (FLT1) with a high affinity, whereas it binds to VEGF receptor-2 (KDR) with a low affinity (By similarity).
What are the official names of this protein?
Snake venom vascular endothelial growth factor toxin cratrin, svVEGF, VEGF-F.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family. Snake venom VEGF subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ERG10_SACMO
Sequence: MSQNVYIVSTARTPIGSFQGSLSSKTAVELGAAALKGALAKVPELDASKDFDEIIFGNVLSANLGQAPARQVALTAGLGNHIVATTVNKVCASAMKAIILGAQSIKCGNADVVVAGGCESMTNAPYYMPAARGGAKFGQTVLIDGVERDGLNDAYDGLAMGVHAEKCARDWDITRDQQDSFAIESYQKSQQSQKEGKFDNEIVPVTIKGFRGKPDTQVTNDEEPARLHVEKLKSARTVFQRENGTVTAANASPINDGAAAIILVSERVLKEKNLKPLAIVKGWGEAAHLPADFTWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLGCSGARVVVTLLSILQQEGGKIGVAAICNGGGGASSVVIEKL
What is the function of this protein?
Acetyl-CoA acetyltransferase; part of the first module of ergosterol biosynthesis pathway that includes the early steps of the pathway, conserved across all eukaryotes, and which results in the formation of mevalonate from acetyl-coenzyme A (acetyl-CoA) (PubMed:2900076).  In this module, the acetyl-CoA acetyltransferase ERG10 catalyzes the formation of acetoacetyl-CoA (PubMed:2900076).  The hydroxymethylglutaryl-CoA synthase ERG13 then condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA (By similarity).  The rate-limiting step of the early module is the reduction to mevalonate by the 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductases HMG1 and HMG2 which are derived from a single ancestral HMGR gene by gene duplication (By similarity).
What are the official names of this protein?
Acetyl-CoA acetyltransferase, Acetoacetyl-CoA thiolase, Ergosterol biosynthesis protein 10.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BSHC_STAA9
Sequence: MDCKVVSLNEKDQFIPKIKSSDPVITGLFQYDAAQQTSFEKRMSKENNGREAALANVIREYMSDLKLSNEQELNIQHLANGSKVVIGGQQAGLFGGPLYTFHKIFSIITLSKELTDTHKQQVVPVFWIAGEDHDFDEVNHTFVYNENHGSLHKVKYHTMEMPETTVSRYYPDKAELKQTLKTMFIHMKETVHTQGLLEICDRIIDQYDSWTDMFKALLHETFKAYGVLFIDAQFEPLRKMEAPMFKKILKKHQLLDDAFRATQQRTQNQGLNAMIQTDTNVHLFLHDENMRQLVSYDGKHFKLNKTDKTYIKEEIINIAENQPELFSNNVVTRPLMEEWLFNTVAFVGGPSEIKYWAELKDVFELFDVEMPIVMPRLRITYLNDRIEKLLSKYNIPLEKVLVDGVEGERSKFIREQASHQFIEKVEGMIEQQRRLNKDLLDEVAGNQNNINLVNKNNEIHIQQYDYLLKRYLLNIERENDISMKQFREIQETLHPMGGLQERIWNPLQILNDFGTDVFKPSTYPPLSYTFDHIIIKP
What is the function of this protein?
Involved in bacillithiol (BSH) biosynthesis.  May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
What are the official names of this protein?
Putative cysteine ligase BshC.
What is the protein family that this protein belongs to?
Belongs to the BshC family.
Protein: GCSP_SALA4
Sequence: MTQTLSQLENRGAFIERHIGPDAAQQQEMLNAVGAESLNALTGQIVPKDIQLATPPQVGEAATEYAALAELKAIAGRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFDVIVDDAAKALDHQDVFGVLLQQVGSTGEIHDYSALISELKARKVIVSVAADFMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEFKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAAVLARAEAAEINLRSDIHNAVGITLDETTTRENVAQLFNVLLGDSHGLNIETLDKDVALDSRSIQQSMLRDDAILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYHQMISQLSDWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLDDLRAKAEQHAANLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGMKQASQVAILNANYIASRLKDAYPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESEGKAELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISDYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: 3S33_PSETE
Sequence: MKTLLLTLVMVTIMCLDLGYTLTCYKGYHDTVVCKPHETICYRYLVPATHGNAIPARGCGTSCPGGNHPVCCSTDLCNK
What is the function of this protein?
Binds with high affinity to muscle nicotinic acetylcholine receptor (nAChR) and hinders acetylcholine binding to the receptor, thereby impairing neuromuscular transmission.  Competes with the binding of alpha-bungarotoxin on muscle AChR (from Torpedo) with an IC(50) of 0. 30 uM.  Causes muscle paralysis, spasms and increased respiration.
What are the official names of this protein?
Short neurotoxin 3, SNTX3, Alpha-neurotoxin 3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type III alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.