PharMolix/UniProtQA huggingface dataset:
Protein: CDKL5_MOUSE
Sequence: MKIPNIGNVMNKFEILGVVGEGAYGVVLKCRHKETHEIVAIKKFKDSEENEEVKETTLRELKMLRTLKQENIVELKEAFRRRGKLYLVFEYVEKNMLELLEEMPNGVPPEKVKSYIYQLIKAIHWCHKNDIVHRDIKPENLLISHNDVLKLCDFGFARNLSEGNNANYTEYVATRWYRSPELLLGAPYGKSVDMWSVGCILGELSDGQPLFPGESEIDQLFTIQKVLGPLPSEQMKLFYSNPRFHGLRFPAVNHPQSLERRYLGILNSVLLDLMKNLLKLDPADRYLTEQCLNHPTFQTQRLLDRSPSRSTKRKPYHVESSTLSNRNQSTKGAALQTHHRSNSKDIQNLSVGLPRAEEGLPANESFLNGNLAGATLSPMHTKTYQASTQPGSSSKDLTNNNIPHLLSPKEAKSKTEFDFNIDTKPSEGPGTKYLKSSTRSQQNRHSFMESSQSKAGTLQPSEKQSRHSYIDTIPQSSRSPSYRTKAKSHGALSDSKSVSNLSEARAQITETNTSRYFPSSCLDLNSPTSPTPTRHTDTRTLLSPSGRNNRNEGTLDSRRTTTRHSKTMEELKLPEHMDSSHSHSLSAPHESFSYGLGYTSPFSSQQRPHRHSMYVTRDKVRAKGLDGSLSIGQGMAARANSLQLLSPQPGEQLPPEMTVARPSVKESSREGASSFHTRQKSEGGVYHDPHSDDGTAPKENRHLYNDPVPRRVGSFYRVPSPRPDNSFHENNVSTRVSSLPSDSSSGTNHSKRQPGFDPWKSPENISHADQLKEKEKQGFFRSMKKKKKKTQTVPNTDGPDLLTLQKAIHSSSTASSRPKEWRPEKLSDLQTQSQPLKSLRKLLHLSSSTNHPASSDPRFQPLTAQQAKNSFSEIRIHPLSQATGGSSNIRQEPTPKGRPALQLPGSSLLRYNGWKHSRSRSSQPDEVIFLASHEKWKQ
What is the function of this protein?
Mediates phosphorylation of MECP2.  May regulate ciliogenesis.
What are the official names of this protein?
Cyclin-dependent kinase-like 5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: O1038_MOUSE
Sequence: MAEVNISYVSEFILKGITDRPELQAPCFVMFLTIYLVTVLGNLGLIVIIRVDSRLHTPMYFFLSHLAFVDLCYSSAITPKMMVNFVVERNTIPFHACATQLGCFLTFMITECFLLASMAYDRYVAICSPLHYSTLMSKRVCIQLVAVPYVYSFLVALFHTIITFRLTYCGPNVINHFYCDDLPLLALSCSDTHMKEILIFAFAGFDMICSSSIVLTSYLFIIAAILRIRSTQGRRKAISTCGSHMVAVTIFYGTLIFMYLQPKSNHSLDTDKMASVFYTVVIPMLNPLIYSLRNKEVKDASKKALDKGYETLKILRLSK
What is the function of this protein?
Potential odorant receptor.
What are the official names of this protein?
Olfactory receptor 1038, Olfactory receptor 185-3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUON_METNO
Sequence: MNAAEIVMPALGPALPELILTVGALVLILYGALRGERSTEGVTVGAIIVLIVALFSVVSQPLGAKITTFNGSFIVDGFARVMKTLTLVGSLAALLLARDLFARERIERFEYPILIVLSSIGMLIMASANDLIGLYLGLELQSLAAYVIASFHRDDVRSTEAGLKYFVLGALSSGMLLYGASLVYGFTGSVSFPGIVTALREAHAGLGLVLGIVFVAAGVAFKLAAVPFHMWTPDVYEGAPTPVTAFFASAPKMAAMAMTVRVFIGAFPGVVAEWQQIIVFIAIASMALGSFAAIGQRNLKRLMAYSSIGNVGYALIGLAAGTEEGVRGVVVYMAIYLAMTLGAFAVILGMRRGNRMFETIEDLSGLSRTHPWLAFCLAMMMFSLAGIPPLAGFFAKFYVFAAAIKAGLNVLAVIGVVTSVVGAYYYVRIVKIMYFDDAQAAYEPLAPGLRIVLAASSVVVVLFWIVPAPLVAAAGTAARSLF
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEXA_PORGI
Sequence: MKRLTFGACICCLLSLMACSQKAKQVQIPEYDKGINIIPLPMQLTESDDSFEVDDKTTICVSAEELKPIAKLLADKLRASADLSLQIEIGEEPSGNAIYIGVDTALPLKEEGYMLRSDKRGVSIIGKSAHGAFYGMQTLLQLLPAEVESSNEVLLPMTVPGVEIKDEPAFGYRGFMLDVCRHFLSVEDIKKHIDIMAMFKINRFHWHLTEDQAWRIEIKKYPRLTEVGSTRTEGDGTQYSGFYTQEQVRDIVQYASDRFITVIPEIEMPGHAMAALAAYPQLACFPREFKPRIIWGVEQDVYCAGKDSVFRFISDVIDEVAPLFPGTYFHIGGDECPKDRWKACSLCQKRMRDNGLKDEHELQSYFIKQAEKVLQKHGKRLIGWDEILEGGLAPSATVMSWRGEDGGIAAANMNHDVIMTPGSGGLYLDHYQGDPTVEPVAIGGYAPLEQVYAYNPLPKELPADKHRYVLGAQANLWAEYLYTSERYDYQAYPRLLAVAELTWTPLAKKDFADFCRRLDNACVRLDMHGINYHIPLPEQPGGSSDFIAFTDKAKLTFTTSRPMKMVYTLDETEPTLTSTPYTVPLEFAQTGLLKIRTVTAGGKMSPVRRIRVEKQPFNMSMEVPAPKPGLTIRTAYGDLYDVPDLQQVASWEVGTVSSLEEIMHGKEKITSPEVLERRVVEATGYVLIPEDGVYEFSTENNEFWIDNVKLIDNVGEVKKFSRRNSSRALQKGYHPIKTIWVGAIQGGWPTYWNYSRVMIRLKGEEKFKPISSDMLFQ
What are the official names of this protein?
Beta-hexosaminidase, Beta-GlcNAcase, Beta-N-acetylhexosaminidase, Beta-NAHase, N-acetyl-beta-glucosaminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 20 family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: AB53G_ORYSJ
Sequence: MDDAGEIHALGGSLRREASSARSGDAAVFFSRSSSRDEDDEEALRWAALEKLPTYDRARTAVLAMPEGELREVNVQRLGPQERHALLQRLAWVGDDHARFLSKFKDRVDRVGIELPTIEVRYENLNVEAEAYVGSRGLPTILNTYANVLEGLANTLHITPNRKQKISILHNVSGIIKPHRMTLLLGPPGAGKTTLLLALAGNVPSGLKVSGQITYNGHTMDEFEPRRSAAYVSQHDLHMGELTVRETVNFSAKCQGIGHRYDLLMELSRREKEENIKPDPEVDIYLKAAATGEQKAEVVTNHILKVLGLDICADTIVGNNMLRGISGGQKKRVTTAEMIVTPGRALFMDEISTGLDSSTTYNIVDSIRQTIHIVGGTAVIALLQPAPETYELFDDIILLSDGQVVYNGPREHVLEFFESVGFKCPERKGVADFLQEVTSRKDQRQYWMHGDETYRYVPVKEFAEAFQSFHVGQAIRSELAIPFDKSRSHPAALKTSKYGASMKELLKANIDREILLMKRNSFVYIFKATQLTLMTFIAMTVFIRTNMHHDSITNGGIYMGALFFGILMIMFNGLAEVGLTIAKLPVFFKQRDLLFYPAWTYSLPSWIIKTPLSLLNVTIWVFITYYVIGFDPNVERLFRQFLLLLVMNETSSGLFRFIAGFARHQVVASTMGSFCILIFMLLGGFILSRENVKKWWIWGYWISPLMYAQNAISVNEFLGHSWNKTIPGFREPLGKLVLESRGVFPEAKWYWIGVGALLGYVLLFNILYTICLTFLNPFDSNQPTISEETLKIKQANLTGDVIEASSRGRITTNTNTADDSNDEAISNHATVNSSPGKKGMVLPFVPLSITFEDIRYSVDMPEVIKAQGVTESRLELLKGISGSFRPGVLTALMGVSGAGKTTLMDVLAGRKTSGYIEGNITISGYPKKQETFARVSGYCEQNDIHSPNVTVYESLAFSAWLRLPAEIDSATRKMFIDEVMELVELSPLKDSLVGLPGVSGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRAIRNTVDTGRTVVCTIHQPSIDIFESFDELFLMKRGGEEIYVGPVGQHSCELIRYFESIEGVSKIKHGYNPSTWMLEVTSTVQEQITGVNFSEIYKNSELYRRNKSMIKELSSPPDGSSDLSFPTEYSQTFITQCLACLWKQSLSYWRNPPYTAVKYFYTIVIALLFGTMFWGVGRKRSNQQDLFNAMGSMYASVLFMGVQNSSSVQPVVSVERTVFYRERAAHMYSPLPYALGQVAIELPYILVQSLIYGVLVYAMIGFEWTAAKFFWYLFFMYFTLSYYTFYGMMSVGLTPSYNVASVVSTAFYAIWNLFSGFIIPRTRIPIWWRWYYWVCPVAWTLYGLVTSQFGDVTDTFDNGVRISDFVESYFGYHRDFLWVVAVMVVSFAVLFAFLFGLSIKIFNFQKR
What is the function of this protein?
May be a general defense protein.
What are the official names of this protein?
ABC transporter G family member 53, OsABCG53, Pleiotropic drug resistance protein 20, OsPDR20.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDRP_RICRS
Sequence: MTKLIIHLVSDSSVQTAKYAANSALAQFTSVKPKLYHWPMIRNLELLNEVLSKIEYKHGIVLYTIADQELRKTLTKFCYELKIPCISVIGKIIKEMSVFSGIEIEKEQNYNYKFDKTYFDTLNAIDYAIRHDDGQMLNELSEADIILIGPSRTSKTPTSVFLAYNGLKAANIPYVYNCPFPDFIEKDIDQLVVGLVINPNRLIEIREARLNLLQINENKSYTDFNIVQKECLEVRKICDQRNWPVIDVSTRSIEETAALIMRIYYNRKNKYNK
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RSMA_SYNJB
Sequence: MPYPRKRFGQHWLKDPAVHEAILRAAQLNDLERGADPTWVLEIGPGTGQLTRRLLAQGVQVVAVEIDRDLCRLLRKRFADQPRFHLVEGDFLRLPLPPQPRLLVANIPYNLTGSILEKVLGSPAQPVRQFERIVLLVQKELAERLQAGPGSKAYGALSLRTQYLADCELICRVPPTAFKPAPKVESAVIRLTPRPAPTPVRDPCWFNHLLRQGFSTRRKKLVNALGSLVEREVVAAALAQLRLNPDARAEELDLPHWLALSDLLLEKAPKRAVVPQEEQEPG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADE_STAAB
Sequence: MSKLQDVIVQEMKVKKRIDSAEEIMELKQFIKNYVQSHSFIKSLVLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAVKLPYGVQKDADEVEQALRFIEPDEIVTVNIKPAVDQSVQSLKEAGIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTDHSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKELYEKTPTADLEDDKPQLPDEDALGVTYEAIDNYLEGKPVSPEEQKVIENHYIRNAHKRELAYTRYTWPKS
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: BZP28_ARATH
Sequence: MTESTSVVAPPPEIPNLNPSMFSESDLFSIPPLDPLFLSDSDPISMDAPISDLDFLLDDENGDFADFDFSFDNSDDFFDFDLSEPAVVIPEEIGNNRSNLDSSENRSGDGGLEGRSESVHSQVSSQGSKTFVSDTVDASSSPESSNHQKSSVSKRKKENGDSSGELRSCKYQKSDDKSVATNNEGDDDDDKRKLIRQIRNRESAQLSRLRKKQQTEELERKVKSMNATIAELNGKIAYVMAENVALRQQMAVASGAPPMNPYMAAPPLPYQWMPYPPYPVRGYGSQTPLVPIPKLNPKPVSSCRPKKAESKKNEGKSKLKKVASISFIGILFFVFLFGTLVPFMNVNFGGERGSFGGLSKYDGHRYYDEHKGRVLMVGDGSDVRRNSGISEGNIHSSRISHGERDSCGGVDYNAHPKVEGRPSSLSNASDPLFASLYVPRNDGLVKIDGNLIIHSVLASEKARGLGKKNITETVKTKEPDLTIPGALSSALAVPGVRGNAAMLPHSTALSSEGKRLHQWFHEGGSGPLMDYSMCTEVFQFDIAPGAIVPSSVSSISAEHLQNVTTHGKRMKNRRILEGLPVSLVASELNITGTQPNKDAQNKTFNGNTNKPTSSSSMVVSVLLDPREVVDSETDRVVPPNPKSLSRIFVVVLLDSVKYVTYSCVLPRSGLHLVAT
What is the function of this protein?
Transcriptional activator involved in ER stress responses.  Functions as a stress sensor and transducer in ER stress signaling pathway.  After proteolysis by SBT6. 1 (S1P) and S2P, the N-terminal bZIP component is translocated to the nucleus, where it activates the expression and production of ER chaperones (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872).  Following ER stress, activates proteins involved in brassinosteroid (BR) signaling, which is required for stress acclimation and growth (PubMed:20876872).
What are the official names of this protein?
bZIP transcription factor 28, AtbZIP28.
What is the protein family that this protein belongs to?
Belongs to the bZIP family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Nucleus. Note=Translocates to the nucleus following heat shock or tunicamycin treatment (ER stress) (PubMed:18156219, PubMed:18634751, PubMed:18849477, PubMed:20876872, PubMed:22335396, PubMed:23558471, PubMed:23624714). Relocation of BZIP28 from ER to the nucleus occurs through the Golgi and is S2P-dependent (PubMed:20876872, PubMed:22335396, PubMed:23558471, PubMed:23624714).
Protein: PTAS_CORGL
Sequence: MSAELFENWLLKRARAEHSHIVLPEGDDDRILMAAHQLLDQDICDITILGDPVKIKERATELGLHLNTAYLVNPLTDPRLEEFAEQFAELRKSKSVTIDEAREIMKDISYFGTMMVHNGDADGMVSGAANTTAHTIKPSFQIIKTVPEASVVSSIFLMVLRGRLWAFGDCAVNPNPTAEQLGEIAVVSAKTAAQFGIDPRVAILSYSTGNSGGGSDVDRAIDALAEARRLNPELCVDGPLQFDAAVDPGVARKKMPDSDVAGQANVFIFPDLEAGNIGYKTAQRTGHALAVGPILQGLNKPVNDLSRGATVPDIVNTVAITAIQAGGRS
What are the official names of this protein?
Phosphate acetyltransferase, Phosphotransacetylase.
What is the protein family that this protein belongs to?
Belongs to the phosphate acetyltransferase and butyryltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1748_GEOSL
Sequence: MTEARIRIESLAFGGAGFGRLEGKACFVPFTAPGDLVRIRVAVDKPSYLEGETLEILEPSPDRIAPPCPVFGICGGCSWQHLRYDAQAEAKERIFVDTLWRFGRVERDAVAPFAVADNPFGYRCRAQFKIRWSGGRLHMGFYRRGSHYVIDAPAECVICDPAINLTLRDLRLVLPDFSEPDKIPQIDAATGEDGHVLLVVHYIGDNPGRAADFFRSIQPHLASVTGIHLQCGRKDSIMHVWGVDSLSYTVPGLGDQGRPLSLSFRRGGFSQVNYRQNRVLVSKALHLAGVGPGRRVLDLFCGNGNFSLPLASGGAQLVGVEDYGPSIDDARKNADFNGIGDVEFIAIDAADGTRRLRAAGEHFDTVILDPPRTGARDAVGEVAILAPERIVYVSCDPPTLGRDLGVLRKAGYRVVGSHGVDMFPQTYHIESVTLLIRS
What are the official names of this protein?
Uncharacterized RNA methyltransferase GSU1748.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: EFTS_CORGL
Sequence: MANYTAADVKKLRELTGSGMLDCKKALEESAGDFDKAVEILRVKGAKDVGKRAERNATEGLVAVSGNTMVEVNSETDFVAKNSDFKEFAAKVADAAAAAKANSQEELAAVDVDGQTADAALQEFSAKIGEKLELRRAVTLEGDKTAVYLHQRSADLPPAVGVLVAFTGEGEAAEAAARQAAMQIAALKASYLTREDVPAEIIEKERSIAEQITREEGKPEQAIPKIVEGRLNGFYKENVLLEQSSVADSKKTVKALLDEAGVTVTSFARFEVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 1105L_ASFWA
Sequence: MLVIFLGILGLLANQVSSQLVGQLHPTENPSENELEYWCTYMECCQFCWDCQNGLCVNKLGNTTILENEYVHPCIVSRWLNKCMYDLGQGIDHVMVCSQPKYWNPYKILKKEWKENNSQNK
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 110-5L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 110 family.
Protein: PROA_MYCBT
Sequence: MTVPAPSQLDLRQEVHDAARRARVAARRLASLPTTVKDRALHAAADELLAHRDQILAANAEDLNAAREADTPAAMLDRLSLNPQRVDGIAAGLRQVAGLRDPVGEVLRGYTLPNGLQLRQQRVPLGVVGMIYEGRPNVTVDAFGLTLKSGNAALLRGSSSAAKSNEALVAVLRTALVGLELPADAVQLLSAADRATVTHLIQARGLVDVVIPRGGAGLIEAVVRDAQVPTIETGVGNCHVYVHQAADLDVAERILLNSKTRRPSVCNAAETLLVDAAIAETALPRLLAALQHAGVTVHLDPDEADLRREYLSLDIAVAVVDGVDAAIAHINEYGTGHTEAIVTTNLDAAQRFTEQIDAAAVMVNASTAFTDGEQFGFGAEIGISTQKLHARGPMGLPELTSTKWIAWGAGHTRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_ACIF5
Sequence: MDAHTIIVAATAIAVGIIFGAAGLGSAIGWGLITSKTIEGITRQPEMRPQLLVNTFIFAGLMESFPFIILAFGFWFLFANPFLG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLYA_POLSJ
Sequence: MYHRNILVEQTDPEIFAAIQAENARQEHHIELIASENYASPAVMAAQGSQLTNKYAEGYPGRRYYGGCEYVDVAEQLAIDRIKQIFGADAANVQPHCGASANEAVFLAFLKPGDTIMGMSLAEGGHLTHGMALNMSGKWFNVVSYGLNDKEEIDYDAMERKAHETRPKLIIAGASAYSLRIDFERFAKVAKAVGAIFMVDIAHYAGLVAAGVYPNPVPHADVVTSTTHKSLRGPRGGIILMKAEHEKAINSAIFPGLQGGPLMHVIAAKAVAFKEALSPEFKTYQQQVLTNARIVAETLTQRGLRIVSGRTESHLMLVDLRAKGITGKEAEAVLGSAHMTINKNAIPNDPEKPMVTSGVRIGTPAMTTRGFKDEEARVTANLIADVLDNPRDAANIEAVRAKVNALTSRFPVYR
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6C_OLIPU
Sequence: MDLPGPIHDFLLVFLGSGLLVGGLGVVLLPNPIFSAFSLGFVLVCISLLYILSNSHFVAAAQLLIYVGAINVLIIFAVMFMNDSEYSTDFNLWTVGNGITSLVCTTILFLLMSTILDTSWYGVIWTTRLNQILEQDLISNSQQIGIHLSTDFFLPFELISIILLVALIGAISVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: MU163_SCHPO
Sequence: MPFMNFRNFNFMPLLRPLNPVYKGAEHLCRKNIHNQVYNVETGKTIQILQDLVPLVLYRALPDAILDHHVELVIFPNSLNFPRIEGLTIYKFIFKTARLLLSSTYGSSAKRPIDIIHQLHSSMENKNVRYSMKCNWIASPNDEYTWVFHFDIDKKGIIYRHIIDNLERNRSRQCEKISALKPDPIE
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 163 protein.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RPPH_BARHE
Sequence: MDAVVNLTTLPYRRSVGILVFNHEGKVWVGRRLMVCIHEDTKIYHRWQLPQGGIDENEEPLDAARRELYEETGIRSIELIKEAKYWFHYDFPQEIVGSVLGSKYRGQIQKWFAFQFTGELSEIKINPPPDGHKAEFDQWKWVDLETLPSIVISFKKHVYMKIVNEFRGSFKGL
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: RPPH_BLOFL
Sequence: MIDDNGYRLNVGIVLCNTYGQVLWAKRYKQCSWQFPQGGINIGETPEQAMYRELFEEIGLNYCDVRILSITRCWFCYKLPTQLVRWRIKPLCLGQKQKWFLLKLLSKDTKINMKTSKVCTFDTWQWVSLWYPIRQVVFFKRHVYRKVMKEFVKLIISR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: LOLB_YERPE
Sequence: MPMRKRHFYRLLPLASLLLAACTIPVSKGPATSPTSPQWRQHEQQLQQLGQFETRGAFAYLSDKQKVYARFFWQQTSPERYRLLLTNPLGSTELELVVQPGVTQLTDNQGKRYVSDDPQEMIQKLTGMSIPLESLRQWILGLPGDTSDFTLDDKYRLKKLTYQQNGVTWVVDYQEYNTQVTPSLPSRLELNQDGQRIKLKMDSWTIK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: IF414_TOBAC
Sequence: MAGLAPEGSQFDARQYDAKMTELLGTEQEEFFTSYDEVYDSFDAMGLQENLLRGIYAYGFEKPSAIQQRGIVPFCKGLDVIQQAQSGTGKTATFCSGVLQQLDYSLVECQALVLAPTRELAQQIEKVMRALGDYLGVKVHACVGGTSVREDQRILQSGVHVVVGTPGRVFDMLRRQSLRPDHIKMFVLDEADEMLSRGFKDQIYDIFQLLPPKIQVGVFSATMPPEALEITRKFMSKPVRILVKRDDVTLEGIKQFYVNVDKEEWKLETLCDLYETLAITQSVIFVNTRRKVDWLTDKMRSRDHTVSATHGDMDQNTRDIIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTQPENYLHRIGRSGRFGRKGVAINFVTKDDERMLFDIQKFYNVVIEELPANVADLL
What is the function of this protein?
ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome.  In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity).
What are the official names of this protein?
Eukaryotic initiation factor 4A-14, eIF-4A-14, ATP-dependent RNA helicase eIF4A-14.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. eIF4A subfamily.
Protein: COAE_STRPN
Sequence: MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGGRLFEALVQHFGQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQLAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAAQWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2143_SULTO
Sequence: MSVKIFNGEFDIPENSRSLYILVIATTDISLIPGLTVAGATPELTHFTPAADAEFLIKGKCSVINTVPVTPNGIPTPAIITRASLEFVKIPRLVVNAGSRIKPNLPLIDLGGEPGGDIRKGSLRKEVAERILNNGVSLGEEFSNSFDFLIIGESIPAGTTTAMAVLVGLGYDALDKVSSASPENPKELKKKIVYEAIKDLPSDLMGKLAKLSDPMLLGVSGIALGFKGKILLAGGTQMTAAAAIIKEFNKNKLKDIAIGTTKWIINDRSSDIIGLAKAVGIPILAAWLDFTNSKFEGLKVYEKGFVKEGVGAGGASIYAMKRGVTNEQILGKVEEIYQRITTNLM
What are the official names of this protein?
UPF0284 protein STK_21430.
What is the protein family that this protein belongs to?
Belongs to the UPF0284 family.
Protein: ARCA_MYCA1
Sequence: MGVVELGTNSEVGALRVVILHRPGGELLRLNPRNVDQLLFDGLPWVARAQEEHDQFAELLRSRGVEVLLLSDLLTEALTHSGAARMQGVAAAVDARRLGVPLAQELSAYLRGLEPARLAQVLMAGMTFNELPADTRTDVSLVLRMHHGGDFVIDPLPNLVFTRDSSIWIGPRVVIPTLALRARVREASLTDLIYAHHPRFTGVRRAYESRTAPVEGGDVLLLAPGVVAVGVGERTTPAGAEALARSLFDDDLAHTVLAVPIAQRRAQMHLDTVCTMVDTDTVVMYANVVDALSAFTIQRTPSGVEISEAPFLEAAATAMGIDKLRVIDTGLDPVIAEREQWDDGNNTLALSPGVVVAYERNAQTNMRLQEAGIEVLTIAGSELGTGRGGPRCMSCPVARDPL
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTF2_BOVIN
Sequence: MGCDGGTIPKRHELVKGPKKVEKVDKDAELVAQWNYCTLSQEILRRPIVACELGRLYNKDAVIEFLLDKSSEKALGKAASHIKSIKNVTELRLSDNPAWEGDKGNTKGDKHDDLQRARFICPVVGLEMNGRHRFCFLRCCGCVFSERALKEIKAEVCHTCGAAFQEDDVIVLNGTKEDVEVLKSRIEERRLRAKLGKKTKKPKVAESVSKSEVSEETPGPSKVKTGKPEETSLDTREKKTNSAPKSAAAHGITSGKAAKRSIADSEESEAYKSLFTTHSSAKRSKEESAHWVTHTSYCF
What is the function of this protein?
Replication termination factor which is a component of the elongating replisome.  Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication.  Might function to facilitate fork pausing at replication fork barriers like the rDNA.  May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion.  Interacts with nascent DNA.
What are the official names of this protein?
Replication termination factor 2, RTF2, Replication termination factor 2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the rtf2 family.
What are the subcellular locations of this protein?
Chromosome. Note=Localizes at the replication fork.