PharMolix/UniProtQA huggingface dataset:
Protein: IPYR_BACP3
Sequence: MAFENKIVEAFIEIPTGSQNKYEFDKERGIFKLDRVLYSPMFYPAEYGYLQNTLALDGDPLDILVITTNPPFPGCVIDTRVIGYLNMVDSGEEDAKLIGVPVEDPRFDEVRSIEDLPQHKLKEIAHFFERYKDLQGKRTEIGTWEGPEAAAKLIDECIARYNEQK
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRM_DANRE
Sequence: MASVTFRDGFLCVSALITFVFVFVTGADFVRFVSFRAINHNLSGAAPLCRDSVPWSVALRDGVVQKAVAVDVLLLVVFSLQHSLLAWTPVKRVCQSVFGVLSRSVYCFTTAAALQILMHYWRPVTSAPCLWSVSSAPWEIWFPLICFIVHFLCWAIICSILLIFDYPELLGIKQVYYECLGLGDPLLLKSERAQRLYSHLRHPVCVELLTVLWLLPSFPLDRLLLAVFLTVYLILAHSLDKQDCAYLRHQLRNKLQLFSTPLEGSEQTNDNNKLE
What are the official names of this protein?
Nurim, Nuclear envelope membrane protein, Nuclear rim protein.
What is the protein family that this protein belongs to?
Belongs to the nurim family.
What are the subcellular locations of this protein?
Nucleus inner membrane; Multi-pass membrane protein.
Protein: RL7_PSYCK
Sequence: MALSKDDVLNAIAEMSVMDIVELISAMEEKFGVTAAVAAAPAAAGPAAAAAEEKDEFDVVLASFGEKKVGVIKAVREATGLGLKEAKDLVESAPAPIKEGVNKAEAEELKKKLEEAGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y1405_RHOPS
Sequence: MATSAAAVQDEPATRFAKDQLKAIIERIERLEEEKKTISDDIRDVYAEAKGNGYDVKALRTIVRMRKQDANERAEQETILETYMQALGML
What are the official names of this protein?
UPF0335 protein RPD_1405.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: TRMD_SHEPC
Sequence: MWLGVITLFPEMFRAVTDFGVTGRAVKNGLLELHTWNPRDFTHDRHNTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEEAKVIYLSPQGRKLDQQGVTELAKSSRLILVCGRYEGIDERIIQTEVDEEWSVGDYVLSGGELPAMTMIDAVSRLVPGVLGKQASAEQDSFSDGLLDCPHYTRPESLDGLDVPAVLLSGNHEQIRLWRLQQSLGRTLLRRPELLQNLALTDEQSTLLAQFVEAMDKHA
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPPA2_METMA
Sequence: MERLIFTAPLAGLISLTFAAFFAKSILKEDAGNKRMKEIAEAIKEGSTAYMKRQYRTIAVVSVIISLLILFLLDEGLKIAAGFLAGAISSAAAGYIGMSISVRANVRTASAASGGAGKALKIAFRGGAVTGLAVIGLALLGTSSLYILYGDADLVVGFGFGASLISLFARAGGGIFTKAADVGADLVGKIEAGIPEDDPRNPAVIADNVGDNVGDCAGMGADLFETYVVTSLAAMLLGSLIIGTYKNAVLYPLMLGSAAIFASIISVFFVKVEKEGKVMSALYRGVGGSTVLSLIAFYYITGFLMGDSRFFYVTVAGVVITVLMVIVTEYYTSKSCRPVKTIAVSSETGAATNIISGLSAGFESTLVPAVVIAAGILVSYFIVGGSADPGTGLYGIAIASVAMLSTAGMIVALDSYGPITDNAGGIAQMANLPAQVRKVTDELDSVGNTTKAVTKGYAIGSTALGALALFADYRNKVSLESQSISLDSPVVLSGILLGAVLPFLFSAVMMSAVGKAAFEVVNEVRRQFREIPGIMEGTAKPEYGRCVDIVTKAALHDMAMPGFLAVIIPLLTGFFLGPEALAGLLTGLIVVGFMLALMMDNGGGAWDNAKKLIEDGYYGGKGSEAHRAAVVGDTVGDPFKDTAGPALNSLIKVVNMVAILFSPLIIGGGFL
What is the function of this protein?
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane.  Generates a proton motive force.
What are the official names of this protein?
K(+)-insensitive pyrophosphate-energized proton pump, Membrane-bound proton-translocating pyrophosphatase, Pyrophosphate-energized inorganic pyrophosphatase, H(+)-PPase.
What is the protein family that this protein belongs to?
Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y582_METJA
Sequence: MKVAIIACQKMVEMGCPGKEACVSCFKAINEKSGAFERYKDVELVAFTTCGGCPGRRFPMRVKLLKTAAGAEAIHIANCTFLQPECPYINFDEICKKLMEELEIPIVFGTHTLVKKGEVVCTCGDNKE
What are the official names of this protein?
Uncharacterized protein MJ0582.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0766.
Protein: NHL26_ARATH
Sequence: MSQISITSPKHCAKKGGININNRHKKLFFTFSTFFSGLLLIIFLVWLILHPERPEFSLTEADIYSLNLTTSSTHLLNSSVQLTLFSKNPNKKVGIYYDKLLVYAAYRGQQITSEASLPPFYQSHEEINLLTAFLQGTELPVAQSFGYQISRERSTGKIIIGMKMDGKLRWKIGTWVSGAYRFNVNCLAIVAFGMNMTTPPLASLQGTRCSTTI
What is the function of this protein?
Involved in the regulation of sugar, amino acid and some primary metabolite export from companion cells (CCs) to sieve elements (SEs) in phloem.  Required for apoplastic phloem sugar loading in source leaves in order to transport it to sink tissues.  Required for correct sugar partitioning between source leaves and sink organs.
What are the official names of this protein?
NDR1/HIN1-like protein 26.
What are the subcellular locations of this protein?
Cell junction, plasmodesma. Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: ISPG_THET8
Sequence: MEGMRRPTPTVYVGRVPIGGAHPIAVQSMTNTPTRDVEATTAQVLELHRAGSEIVRLTVNDEEAAKAVPEIKRRLLAEGAEVPLVGDFHFNGHLLLRKYPKMAEALDKFRINPGTLGRGRHKDEHFAEMIRIAMDLGKPVRIGANWGSLDPALLTELMDRNARRPEPKSAHEVVLEALVESAVRAYEAALEMGLGEDKLVLSAKVSKARDLVWVYRELARRTQAPLHLGLTEAGMGVKGIVASAAALAPLLLEGIGDTIRVSLTPAPGEPRTKEVEVAQEILQALGLRAFAPEVTSCPGCGRTTSTFFQELAEEVSRRLKERLPEWRARYPGVEELKVAVMGCVVNGPGESKHAHIGISLPGAGEEPKAPVYADGKLLTILKGEGIAEEFLRLVEDYVKTRFAPKA
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: Y335_MYCPN
Sequence: MKLFKNWSDVNNVKQRQLLLAYFRFILKQIVKSWLLWVTAGLVLFLLALVLLIIPAFTKQDPLFLWSHPVVQMSSLIIPFIALFATIITFQVFINGYYNGLEILLITRFFTRGRLFFARLAVLFIWITGTAFLSGLFVSLTATLGATSQTVTDLVLSVFFGVLLLSLLFSCVLIIIAQFLNRTQSMLLLLLGVSLASFTTVILAFSIKPPSENLRDNGYQPLNLSLISKSKSKSVENVFTIIDSSNVSDPRNKKKSIVKTNPQAIWDEYGESSFFQSQYYWNVGYWINSLFRLNSLSDYRNFDVNLYFLNTKLNFDREVDTDKMVDFVSFRDQRHLYFLSYSFFINTHNLPTQPLPRILTYDNNGAFLEKIVPSFDDIKLDPPRVKKVYKFFSDTIIQSFRDYEAEEKERQEKEEKEKAEKDNGNGQDSNKVNSVSTEPNNKNSSDADSKDNNDSSDSQGKDSSKSKPKFRPRLPQFFDRVSINYSKFSSSFNTQLKHIHQGLSTRDEAMEIFKDKVALFYALSMAYDNFTFQKDSGIIDNTSLNKFKTEFNKKQKELTEKNKQKQDGKDQKSQRMTQGADKAVTVEPKAMQSEIGMTDQTNDQSSSETKDSMDSSDSSDTVDNTDESEDKQSEEEEKFDEEIENAKKMPKAEDAFFNTASIWLSSPFLFFENGAKREQRYEIHLLNSNTQVNNEIIKTNSFYYVSGEPIVGQEVIIAMVLVVTLGLLVGSFFAYQKRDIK
What are the official names of this protein?
Uncharacterized protein MPN_335.
What is the protein family that this protein belongs to?
To M.pneumoniae MPN_333.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLK4_DROER
Sequence: MLSNRAFGETIEDYEVQHLLGKGGFAIVYKARCLHTHQDVAIKMIDKKLIQGTGLTNRVRQEVEIHSRLKHPSVLQLYTFFQDANYVYLVLELAHNGELHRYMNHIARPFTETEAASILKQVVAGLLYLHSHNIMHRDISLSNLLLSKEMHVKIADFGLATQLKRPDERHMTMCGTPNYISPEVVSRSSHGLPADVWSVGCMLYTLLVGRPPFETDAVQSTLNKVVMSEYIMPAHLSYEAQDLINKLLKKLPHERITLEAVLCHPFMLKCSNGGHSTPGALNMFSQSMESGDSGIITFASSDSRNSQQIRSVENSGPQQVLPQIQEEFKHHKLTYEQPGLFRQTSTGLAEPNWPGATKASSFRMEMGMVQNSKPAPVKEDRISVPPLNTKRLLPTRYKTKNAIMSILRNGEVVLEFFRFRPTYNEDRITDICRISDDGQRIIIYQPDPGRGLPVREQPPDLQIPSGDCVYNYENLPSKHWKKYIYGARFVGLVKSKTPKVTYFSTLGKCQLMETMTDFEIRFYSGAKLLKTPSEGLKVYDRNGMFLSDHSCSESRSLIEHGNECFTHCVNISNALEVAQTKENSCFPVTIGRRPLTDVQPAQRLDGLRDTTNIAFSTPKSNQGSINFSVSTISSTRNTTGFETNCSRSNMLAAHQNIPIKRISVPDVGIATELSHGVVQVQFYDGSVVSVIPSMQGGGITYTQPNGTSTHFGKDDDLPFPVRDRVGQIPNIQLKLKTAPLLESGRKIDYNAMTPKTTTPCYNRMLL
What is the function of this protein?
Serine/threonine-protein kinase that plays a central role in centriole duplication.  Able to trigger procentriole formation on the surface of the mother centriole cylinder, using mother centriole as a platform, leading to the recruitment of centriole biogenesis proteins such as sas-6.  When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase.  Centrosome amplification following overexpression can initiate tumorigenesis, highlighting the importance of centrosome regulation in cancers (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase SAK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
Protein: OL102_ARAHY
Sequence: MTDRTQPHAVQVHTTAGRFGDTAAGTNRYADRGPSTSKVIAVITGLPIGGTLLLFAGLALAGTLLGLAVTTPLFILFSPVIVPATIVVGLSVAGFLTSGACGLTGLSSFSWVMNYIRQTHGSVPEQLEMAKHRMADVAGYVGQKTKDVGQ
What is the function of this protein?
May have a structural role to stabilize the lipid body during desiccation of the seed by preventing coalescence of the oil.  Probably interacts with both lipid and phospholipid moieties of lipid bodies.  May also provide recognition signals for specific lipase anchorage in lipolysis during seedling growth.
What are the official names of this protein?
Oleosin Ara h 10.0102.
What is the protein family that this protein belongs to?
Belongs to the oleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Multi-pass membrane protein. Note=Surface of oil bodies. Oleosins exist at a monolayer lipid/water interface.
Protein: BRAS2_HUMAN
Sequence: MLGWIQPSRQPQLRAAPPTRTPSAKRCILCNFLPGCWLVGDVAGSRQPSAPQTLRQRQHTRPPPQERGSGRRSPLREARRANPHFKSFPVLEARGLPCGARRTGPRRPVREMTLPSDPERATLPNPRLGAPAVPRRGPRSHGGRR
What are the official names of this protein?
Putative uncharacterized protein encoded by BRWD1-AS2, ATP1A1 antisense RNA 1, ATP1A1 antisense gene protein 1, BRWD1 intronic transcript 2.
Protein: RR7_SACHY
Sequence: MSRRGTAEKRTAKSDPIFRNRLVNMVVNRIMKDGKKSLAYQILYRAVKKIQQKTETNPLLVLRQAIRRVTPNIGVKTRRNKKGSTRKVPIEIGSKQGRALAIRWLLEASQKRPGRNMAFKLSSELVDAAKGSGGAIRKKEATHRMAEANRALAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TSAD_BLOPB
Sequence: MRVLGIETSCDETGVAIYDQHKGLLANEVYSQSELHADYGGVVPELAARDHVRKIVPLISCTLNRARLEPKNIDGIAYTAGPGLMGALLVGATVARTLAYAWKIPAIDIHHMEAHLLAPMLEKKVPTFPFIALLVSGGHTQLVSASNIGEYKILGESIDDAVGEVFDKIAILLGLKYPGGALLSKMAQKGISKRYVFPRPMIDRPGLNFSFSGLKTCTVNTIMSNSHDAQNCADIARAFEDAIIETLAIKCRRALNQTGLKCLVISGGVSANHALRSYLLKMMYTLQGSLFYPRPEFCTDNGAMVAYAGLIRLKAGLFSDLPILVRPRWSLEDLPRIKQSL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_SHEB5
Sequence: MTDRYAVFGNPISHSKSPFIHGQFAAPTQESLTYEAILAPVDGFEASLTAFFNAGGKGANVTVPFKEQAFALCDSISPEAKLAGAVNTLSLLADGTIRGDNTDGLGLVADLIANLGSLQDKRVLLIGAGGAARGCILPLLNAGIAQLIISNRTHTKAQLLVDIFTSVDNGAFANRVTAVEMNELAGEFDIIINSTSASLVGELPPLPTHIITTQTVCYDMMYGASVTAFNQWALSQGAAKVIDGLGMLVGQAAKSFTLWRGIEPDTQVVLTLLRDKLMAEPK
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: KDM1B_MOUSE
Sequence: MAASRGRSKKRSNLELSPDNLPLRSSGRQAKKKAVEIPDEDEDGSSEKKYRKCEKAGCTAAYPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYSAWKRVWTSNGKTEPSPKAFMADQQLPYWVQCTKPECGKWRQLTKEIQLTPHMARTYRCGMKPNTITKPDTPDHCSFPEDLRVLEVSNHWWYPMLIQPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRATVTAATTTTGSASPGEMEPSKAAPSSLVLGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLTVAAGQHLLPKHYHNKSVLVVGAGPAGLAAARQLHNFGMKVTVLEAKDRIGGRVWDDKSFKGVVVGRGPQIVNGCINNPVALMCEQLGISMRKLGERCDLIQEGGRITDPTVDKRMDFHFNALLDVVSEWRKDKTLLQDVPLGEKIEEIYRAFVKESGIQFSELEGQVLQFHLSNLEYACGSSLHQVSARSWDHNEFFAQFAGDHTLLTPGYSTIIEKLAEGLDIRLKSPVQSIDYTGDEVQVTTTDGMGHSAQKVLVTVPLAILQRGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASQRGLFAVFYDMDSQQSVLMSVITGEAVASLRTMDDKQVLQQCMGILRELFKEQEIPEPTKYFVTRWSTEPWIQMAYSFVKTFGSGEAYDIIAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF
What is the function of this protein?
Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.  Required for de novo DNA methylation of a subset of imprinted genes during oogenesis.  Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.  Demethylates both mono- and di-methylated 'Lys-4' of histone H3.  Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4 (PubMed:19407342, PubMed:19727073).  Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of GLYR1 to achieve such activity, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes (By similarity).
What are the official names of this protein?
Lysine-specific histone demethylase 1B, Flavin-containing amine oxidase domain-containing protein 1, Lysine-specific histone demethylase 2.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: RECR_CHLTA
Sequence: MLKYPDYISKLISFLKKLPGIGFKSAEKIAFELLEWDPSQIEAMAQALQEFSTSHATCSNCFCLKISQTSPCNFCSESRDSSSLCIVATPKDVFALEKSKIFKGHYFVLGNLLSPITGKHLSLEKLAILKQRIEACSPKEMIIALDATLEGDATALFLKQEFSYLPIKISRLALGMPVGLSFDFVDANTLARAFSGRNCF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RLMC_ACTP7
Sequence: MILNCPHFQQQDCVSCQWLEKPYATQLTDKEIDLKRLISPFILQNFTEILPPVQSSQKQFRNKAKMVVSGSVERPILGILKDQTDPQSGIDLCDCPLYPTEFEALFPILKDFIARAGLVPYNIAKKKGELKYILLTQSRYNQSIMLRFVLKSEQKRPLVERELPNLLAKLPKDSVVSLNIQPQHAAILEGETEIFLTEKTTIEENFNDIPLFIRPQGFFQTNPNVASQLYATAQNWIKDLAIQQFWDLFCGVGGFGLHCAKALQEKNENVQLTSIEISASAIASATKSAEQLQLKNITFASLDSAQFALNEKSATPDLVIVNPPRRGIGKPLAEFLNQLGTPYLIYSSCNARTMAQDFEALSNYSLQKVQLFDMFPHTSHYEVLTFLVKKS
What is the function of this protein?
Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.
What are the official names of this protein?
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC, 23S rRNA(m5U747)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
Protein: IF1_CLOPE
Sequence: MSKSDIIEMQGTVLEALPNAMFEVELESGHKILAHISGKLRMNFIRILPGDKVTVELSPYDLTRGRITWRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOCS6_HUMAN
Sequence: MKKISLKTLRKSFNLNKSKEETDFMVVQQPSLASDFGKDDSLFGSCYGKDMASCDINGEDEKGGKNRSKSESLMGTLKRRLSAKQKSKGKAGTPSGSSADEDTFSSSSAPIVFKDVRAQRPIRSTSLRSHHYSPAPWPLRPTNSEETCIKMEVRVKALVHSSSPSPALNGVRKDFHDLQSETTCQEQANSLKSSASHNGDLHLHLDEHVPVVIGLMPQDYIQYTVPLDEGMYPLEGSRSYCLDSSSPMEVSAVPPQVGGRAFPEDESQVDQDLVVAPEIFVDQSVNGLLIGTTGVMLQSPRAGHDDVPPLSPLLPPMQNNQIQRNFSGLTGTEAHVAESMRCHLNFDPNSAPGVARVYDSVQSSGPMVVTSLTEELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIRDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQVRSLQYLCRFVIRQYTRIDLIQKLPLPNKMKDYLQEKHY
What is the function of this protein?
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction.  May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
What are the official names of this protein?
Suppressor of cytokine signaling 6, SOCS-6, Cytokine-inducible SH2 protein 4, CIS-4, Suppressor of cytokine signaling 4, SOCS-4.
Protein: RS10_COREF
Sequence: MAGQKIRIRLKAYDHEAIDASARKIVETVTRTGARVVGPVPLPTEKNVYAVIRSPHKYKDSREHFEMRTHKRLIDILDPTPKTVDALMRIDLPASVDVNIQ
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GDA9_WHEAT
Sequence: MKTFLILALLAIVATTARIAVRVPVPQLQPQNPSQQQPQEQVPLVQQQQFPGQQQPFPPQQPYPQPQPFPSQQPYLQLQPFPQPQLPYPQPQLPYPQPQLPYPQPQPFRPQQPYPQSQPQYSQPQQPISQQQQQQQQQQQQKQQQQQQQQILQQILQQQLIPCRDVVLQQHSIAYGSSQVLQQSTYQLVQQLCCQQLWQIPEQSRCQAIHNVVHAIILHQQQQQQQQQQQQPLSQVSFQQPQQQYPSGQGSFQPSQQNPQAQGSVQPQQLPQFEEIRNLALETLPAMCNVYIPPYCTIAPVGIFGTN
What is the function of this protein?
Gliadin is the major seed storage protein in wheat.
What are the official names of this protein?
Alpha/beta-gliadin MM1, Prolamin.
What is the protein family that this protein belongs to?
Belongs to the gliadin/glutenin family.
Protein: UNG_ECOLI
Sequence: MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CENPK_MOUSE
Sequence: MSENKQEVHPDTITDVEAVIDTEEELIKECEEMWKDMEDCQNKLSLIGTETLTNADAQLSLLIMQMKCLTAELGQWKKRKPEIIPLNEDVLLTLGKEEFQKLRCDLEMVLSTIQSKNEKLKEDLEREQQWLDEQQQILDTLNVLNSDVENQVVTLTESRIFNELTTKIRGIKEFKEKLLLTLGAFLDNHFPLPEASTPKKRKNIQDSNAQLITLNEILEMLINRMFDVPHDPYVKIRDSFWPPYIELLLRYGIALRHPEDPSQIRLEAFHQ
What is the function of this protein?
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.  Acts in coordination with KNL1 to recruit the NDC80 complex to the outer kinetochore (By similarity).
What are the official names of this protein?
Centromere protein K, CENP-K, SoxLZ/Sox6 leucine zipper-binding protein in testis.
What is the protein family that this protein belongs to?
Belongs to the CENP-K/MCM22 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex (By similarity).
Protein: SYS_SHEB9
Sequence: MLDPKFLRNELEVTAERLATRGFILDIAHLTQLEEKRKSLQVATEELQASRNAISKSIGQAKARGEDVEAIMAQVGDLGSQLDAKKIELAAVLEEVNAIAMSMPNLPDESAPIGADETENVEVRRWGTPRTFDFPIKDHIDLGEGLNGLDFKNAVKITGSRFIVMKGQVARLNRAIGQFMLDLHTTEHGYTEAYVPLLVNEASLLGTGQLPKFGEDLFHTKPATEEGQGLSLIPTAEVPLTNLVRDSIVDEDELPIKLTAHTACFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVKPEDSMAALEALTGHAETVLQRLGLPYRTVILCTGDMGFGSSKTYDIEVWLPAQNTYREISSCSNMKDFQARRMQARYRVKADNKPALLHTLNGSGLAVGRTLVAILENYQNADGSITIPEVLRPYMGGLTQIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAD_STAAN
Sequence: MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
What is the function of this protein?
Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin.
What are the official names of this protein?
Molybdopterin synthase sulfur carrier subunit, MPT synthase subunit 1, Molybdenum cofactor biosynthesis protein D, Molybdopterin-converting factor small subunit, Molybdopterin-converting factor subunit 1, Sulfur carrier protein MoaD.
What is the protein family that this protein belongs to?
Belongs to the MoaD family.
Protein: RS6_STAS1
Sequence: MRTYEVMYIIRPNIEEDAKKAVVERFNGILASHGSEVLEAKDWGKRRLAYEINDFSEGYYNIVRIQTADNEATDEFQRLAKISDDVIRYIVIREDEDKTRK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.