PharMolix/UniProtQA huggingface dataset:
Protein: EIF3A_DEBHA
Sequence: MAPPHRHHNFRPENVYKRAEDLIAVGQRNAALETLYELITSKRIRYLAVQDLEPIALLLIELAVDLRKGKLAKDALHQYKKNVQLSENGLESVQVIVRKFIELAEKKLEEAQAKADVKIDQGEVEDLEAAQTPESILLSAVSNADSADRTERELVNPWLRFLWEALRAVLDILRNNSKLEVTYSAIVNQAFQFCLKFNRKAEFRRLCELLRGHMQSVTTQIKPTGSMNAIDLSDSETVQRYLDQRFAQLNISVKLELWQESFRSVDDVHTLITASKKAPRPVMMANYYENLGRIFAVSGNSLYHAAAWNKFFNLYCQSPNATDDELSHYASILVLATLSVPQKSLNSNETVVDDHKAKNAKLTSLLNLNQVPTRDTLLKSIVSRSILSFVDPAVKQLFTVLEEDEFHPLTIKKKVSEVFQLIESNKDYKQYIPTLTEAILIRLYQQVSQVYETVKLDFLVSLGIIEGTEFSLSALEVENLIVNGVKDGHLSLTIDHETDVVTLKSKPFEDAFTDSLTSKLQISPSELVRSQLSKLAQTLSSSAKVIDPEYEVRIQKTRNEALKNAIADMAREQQEIADRVNVMEERKRIADKAKREQDEEAARLRQEANVAEQKAEQERILAEQERRNLEKLERERQLVKEKEKLKIAEEINAKGIIKLDLNNLDDLDTEKLRIMQIEQLNKDKKDLEERLKVLSKKNDHTERAFRRYELQYLEKDAEKQQEDDIKNYETLKELKISKAKKDHEESLALKDRLQRIVPDFEPFKKIIDEKHSSKLAELRKEAQAALEQAKRERTERVKHQRMDELMERREYERKEAEQEEIKRKRQEEMDKFKEELRIQKEKDADSLRRRQEMANESAKPATPEPVPAPVPAAAAAAAKPSAPLTFAEKMRLKRLGKPGN
What is the function of this protein?
RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit A, eIF3a, Eukaryotic translation initiation factor 3 110 kDa subunit homolog, eIF3 p110, Translation initiation factor eIF3, p110 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_SHESM
Sequence: MSGKKRTASSTRWMQEHFDDHYVKLAQKRGLRSRAAFKLEELQEKDQLIRPGMTVVDLGAAPGGWSQIAVKLTGDKGKVIACDILPMDPIVGVDFLQGDFREEKVLEALLTRVGADKVDVVLSDMAPNMSGSDGVDQPRAMYLVELALDMCHQVLAPNGSFAVKVFQGEGFDEYMKAVKDAFKVVKTRKPDSSRARSREVYLVATGYKL
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PA2HS_ECHOC
Sequence: MRALWIVAVWLIGVEGSVVELGKMIIQETGKSPFPSYTSYGCFCGGGEKGTPKDATDRCCFVHSCCYDKLPDCSPKTDRYKYQRENGEIICENSTSCKKRICECDKAVAVCLRENLQTYNKKYTYYPNFLCKGEPEKC
What is the function of this protein?
Snake venom phospholipase A2 homolog that lacks enzymatic activity.  Shows high myotoxin activities and displays edema-inducing activities (By similarity).  Has cytotoxic activities against HUVEC cells (LC(50)=5. 0 uL) and human lung adenocarcinoma A549 cells (LC(50)=5. 2 uL).
What are the official names of this protein?
Phospholipase A2 homolog, svPLA2 homolog, PLA2-Eoc15.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group II subfamily. S49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RL24_RICRO
Sequence: MIKLKVKKGDEVVVITGKHKGKKGKILKVFPEDSKVIVSGVNVVKKHTKPNQMSEGGIITKELPIHISNIAHIDPKTGNPTKVAFKFLEDGSKVRVAKKSGEIIGKEGK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS18_STRPM
Sequence: MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: JBP1_LEIIN
Sequence: MEPDPKKVKLDIFDFPTARETRTPEEVAESYAEAVKSHPFYDNVHSAIDFYDSGTIKDGRGQIIGVVLREALPKYAASMASELLASAAVRTSLRSMMFGGESPLSGIAGYFDYRGSPVELKSRKTSFTYEHEAAWPAVFPVVDYVSELYRHVAPERWKAQNDAIPDVVRIHGTPFSTLTINSRFRTASHTDVGDFDGGYSCIACLDGQFKGLALAFDDFGINVLMQPRDVMIFDSHHFHSNTEVELSFSGEDWKRLTCVFYYRAALGEPASYAEYRRRLEKSKQDTSFTPVVSNVRVKENGTNLNRPSPVYPIFLSPFWVPMVAHCLQHCASEAQCVHDAMTADGSRLAEVMFGEPLSTSDGIPLRGEEEKLKANSDSASRPLSRLGGFSETNLMVSTAVEKKKYLNSEFLSHFISAQLLDMWKQARGKWLELVGREWTHMLALNPERKDFLWRNQSEMNSAFFDLCEVGKQVMLGLLGKEAALPKEEQAFWTMYAVHLNAACAEELNMPHVAMSLRKLNVKLKDFNFGGTRYFKDMPPEEQKRRMERKQRIEEARRHGMSSGAHEKRANWLTNDSFDYQTEDCVFDYAQHKWVPPALHAKEITKNVRSGELPTREGVVRVLVVLPDPQSKVDCVDCKLEVSETVRCSCEWERLMSSPAVHRVLAAAQRNLQLPDSVTHDNIEIRFAFHSRLPTDMCDFVVLQHVLSCIPDDVLASAYIRRSAALCSGCVFVVETDVQCRQYYTLKCSVRCDYDAVAPLFFQQLHRVSYGTKAARVRTKGELESLIPTVCCARYKLQGSPLNTTVHVVAPAPPR
What is the function of this protein?
Dioxygenase that catalyzes the first step of DNA base J (beta-d-glucosyl-HOMedU) biosynthesis by converting thymine to 5-hydroxymethyluracil (HOMedU).  DNA base J is a hypermodified thymidine residue found in the genome of kinetoplastid parasites, which is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation.  Also specifically binds to base J-containing DNA (J-DNA).  Involved in propagation and maintenance of DNA base J synthesis initiated by JBP2 by specifically binding already synthesized DNA base J and propagating J synthesis.  Thymine dioxygenase activity and J-DNA-binding are independent functions (By similarity).
What are the official names of this protein?
Thymine dioxygenase JBP1, J-binding protein 1, Thymidine hydroxylase JBP1.
What is the protein family that this protein belongs to?
Belongs to the TET family. JBP1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y1754_STRPG
Sequence: MTHNHENDHQHEVITLVDEQGNETLFEILLTIDGREEFGKNYVLLVPAGSEEDESGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEN
What are the official names of this protein?
UPF0473 protein SpyM51754.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: ENTP4_MOUSE
Sequence: MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIVVISILAAAVSLLYFSVVIIRSKYGWLSKDKKFQRYLARVTDVEATDTNNPSVNYGIVVDCGSSGSRIFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLSFAAEHVPRAKHKETPLYILCTAGMRVLPESQQKAILEDLLTDIPVHYDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEEDDEAVVEVNIPGSESSEAIVRKRTAGVLDMGGVSTQIAYEVPQTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRLFASTVQKNRLLGKQTGLTPDAPLLDPCLPLDIKDEIQQNGQTLYLQGTGDFDLCRETLQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAARFTQAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHKGFSFPVTYKNLKTALQVYDKEVQWTLGAILYRTRFLPLRDIRQEVFRAGHAHWRGVSFVYNHYLFSGCFLVVLLSILLYLLRLRRIHRRAPRTGSLWMEEGLPSQKGPGPL
What is the function of this protein?
Has a broad substrate specificity with the ability of cleaving all nucleotide di- and triphosphates with the exception of adenosine di- and triphosphate (ADP and ATP).  Preferentially hydrolyzes CTP, UDP, CDP, GTP and GDP.  Can use either Ca(2+) or Mg(2+) equally.
What are the official names of this protein?
Ectonucleoside triphosphate diphosphohydrolase 4, NTPDase 4, Lysosomal apyrase-like protein of 70 kDa, Uridine-diphosphatase, UDPase.
What is the protein family that this protein belongs to?
Belongs to the GDA1/CD39 NTPase family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform 2]: Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TRPB_MYCLE
Sequence: MMPNLSCFSVAISEPTCHDPDSGGHFGGPDGYGGRYVPEALMAVIEEVTAAYEKERVNQDFLDLLDKLQANYAGRPSPLYEATRLSEYAGSVRIFLKREDLNHTGSHKINNVLGQTLLAQRMGKTRVIAETGAGQHGVATATACALFGLDCVIYMGALDTARQALNVARMRLLGAEVVSVETGSRTLKDAINDAFRDWVTNADNTYYCFGTASGPHPFPTMVRDLQRVIGLETRRQIQYQAGRLPDAVTACIGGGSNAIGIFHAFLDDPGVRLVGFEAAGDGVETGRHAATLTGGLPGAFQGTFSYLLQDEDGQTIESHSIAAGLDYPGVGPEHAWLRETGRAEYQPITDSEAIEAFRLLCRTEGILPALESAHAVAGALKLASEIGKGAVIVVNLSGRGDKDIEAAAKWFGLLGTR
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: SYD_UREPA
Sequence: MKVYCGYIGEEHLEKNVILNGWVKKVRKMGNLVFVDLKDRFGIVQIFATKSDGVFNELTQLSREDVINVEGLVLLRKNPNNDLKTGRFEIHVKKILIYSKAKTPPLIIEDETDANEEIRFRYRYLDLRRDVNLKIFELRSKVYQAFRNYLYSQDFIETETPILAKPTPEGARDFYVPTRTRKFYALPQSPQTFKQLLMVAGFQKYFQITKCFRDEDLRSDRQPEFTQVDIELSFADEIEIQTLIENLLKYVFKQTINVDLTTPFMRMSYEQAINDYGSDKPDLRFDLKIKTLNTYFENSKTLFFQKALLNNQSIRAILVPNINLNKKQVQTLEKFAKDKGAKGLSWISIKDEKIIDGSLLSIQEDHIIYKTIFKDFNLSTGSILLVADTFDIASQALGLVRINLASILNLKKPNIFKFVWIIDWPLYEYDNEAQRFVAAHHPFTMPTLETLNTFDVNKKDARGRSYDIVLNGYELGGGSVRIIDQQIQRRMFKSINMSDEEANLKFGFLLTAFEYGVPPHCGIALGLDRLMMILVNSEYIRDVVAFPKNNNGVDMMLDAPSNMNDEDLKELGLKIKND
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRP1_ONCFA
Sequence: GPSGFLGMR
What are the official names of this protein?
Tachykinin-related peptide 1, TKRP-1.
What are the subcellular locations of this protein?
Secreted.
Protein: CINA_BACP2
Sequence: MKSERKAEIIAVGSELLLGQITNTNAQFISKQLAEIGVNVYYHTAVGDNPERLKRAIQVAQERSNFIIFSGGLGPTKDDLTKETIASTLGKELVLNEEAFESIQEYFRKTGRDMSPNNRKQALVLEGSDVLVNRFGMAPGMFIQENDTFYMLLPGPPSELHPMFENEAKPLISEKLGLKEKIVSVVLRFFGIGESQLETDLEDLIDAQTNPTIAPLASDGEVTLRLTAKHEDEKETERLLKETEAKILARVGEYFYGYGETSLVREASKALRDHGKTVAAAESLTGGMFSEWLTDLEGASSILSGSIVCYTNQVKQQVLGCREETLSSHGAVSKECALELAEGVRKLTGSDIGISFTGVAGPDTHEGQPVGKVFIGLSTKDHTDVFEWMFTGSRSGIRKRAVKYGLHHLLNLLKES
What are the official names of this protein?
Putative competence-damage inducible protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: PXPA_ECO27
Sequence: MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVFAQTLYQIGALAAITRAQGGVMCHVKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGERYGLVTREEVFADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQYGRVKSITGEWAMVTAQTVCLHGDGEHALAFARRLRATFAEKGIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: Y1139_MARMS
Sequence: MPELKTISLFMLTALAEIIGCYLPYLWLREGKTIWLLVPAALSLAVFTWLLTLHPTASGRVYAAYGGVYIFMAVLWLWIVDGIRPTTWDMIGSAVALLGMAIIMFAPRTT
What are the official names of this protein?
UPF0060 membrane protein Mmwyl1_1139.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TLLP_PHONI
Sequence: LSTTCEGKDKGICNLNLALQLITDVRDNFPVCPSPPLPIDCEEVLQRDFKAIPNPIDVYCDMVTDGGGWTVIQRRGDFHGPIDYFYKDWQSYKKGFGDIEKEFWLGNENIFGLSNQRYALYDTFANDDEDHKYMLHISGYKGDAGDSMIGVHNEQKFSTKDKNDNFPGATSCAQLYKGGWWYNQCHVSNLNGQYLKSYADGVIWRSWKGYHESLGWTEIKIKDVK
What is the function of this protein?
Lectin involved in innate immunity.
What are the official names of this protein?
Techylectin-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: SYS_BRUSU
Sequence: MLDIKWIRENPETLDKALAKRGAAPLSSELIALDEKRREHVGKVQAAQERRNAASKEIGKAMAAKDMGTAEKLKAEVGELKDFLAHAEEDERRLSKELSDALSTIPNIPLDDVPLGKDESDNVELRRIGNPHNFSFQPKEHFELGEALGYMDFERAAKLAGARFTVLKGPLARLERALGQFMLDLHTTEHGYTEVMPPLMVRDEAVYGTGQLPKFSEDLFRTTDGRWLIPTAEVPLTNLVAEEIVDMKGLPLRFTALTPCFRSEAGSAGRDTRGMLRQHQFLKVEMVSITDAESSVAEHERMTACAEEVLKRLGLPFRTVVLCTGDMGFGAQRTYDIEVWLPGQNTYREISSCSTCGDFQGRRMNARYRPEGEKSTRFVHTLNGSGVAVGRALIAVMENYQQEDGSIHIPEALQPYIGGLTRIEKAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y992_SYNJB
Sequence: MSVAPPVLVIAGLTGAGKTLAIQQLEQLGYTSLEGIPPAQVIPLVEAMRTHHAALAISLNLHAQEYRDQVPTLAAWVQSQGIPFLFLEARSPVLLNRLSAHRRPHPYGEAAGLWEAIEQERLALAPVRERCTHWLDTSDLNAQQLRQQLQALVQGIPQPLNLRLVSFGFKYGVPPDANLLFDVRFLPNPFFQPHLRRLTGQDPLLQEFLFADPITQSTYQHILSLIKAFWPHYRAERRPHLTLAIGCTGGQHRSVALVERLAQDLQPWTVPAGNHVLPDLNVQVQHRHLLDSQRELEARFGPVPGEAGVAQQQVRIPLAGVPAPSHA
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein CYB_0992.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: CM11_CONTS
Sequence: MLKMGVVLFVFLVLFPLATLQLDADQPVERYAENKQLVSPYERRQIILHALGQRQCCDWQWCDGACDCCA
What are the official names of this protein?
Conotoxin TsMLKM-011, Conotoxin TsMLKM-013.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRE_SALPK
Sequence: MKPYQRQFIEFALNKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDKDLPYCFNRKEAKDHGEGGSLVGSALQGRVMLVDDVITAGTAIRESMEIIQAHRATLAGVLISLDRQERGRGEISAIQEVERDYGCKVISIITLKDLIAYLEEKLDMAEHLAAVRAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: YACL_SALA4
Sequence: MDYEFLRDVTGGVKVRMSMGHEVVGHWFNEEVKDNLSLLDEVEQAARTVKGSERSWQRAGHEYTIWMDGEEVMIRANQLDFSGDEMEEGMSYYDEESLSLCGMEDFLRVVAAYREFVSKA
What are the official names of this protein?
UPF0231 protein YacL.
What is the protein family that this protein belongs to?
Belongs to the UPF0231 family.
Protein: UVRB_LATSS
Sequence: MIDRQNDNLFDLVAPYEPAGDQPAAIETLTKNFEAGAKAQVLMGATGTGKTFTMSNVIKNLNKPTLIISHNKTLAGQLYAEFKQFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSINDEIDKLRHSATSSLLERNDVIVVASVSCIFGLGDPREYQNHVLSLRPGMEVERNDLLRQLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDDHALRVEFFGDEIDRIVEVDALTGEVIGERSHVAIFPATHFMTNDEKMEKAIESIKAELAERLAVLKGEGKLLEAQRLEQRTNYDLEMMQEMGYCSGIENYSRHMEDRQAGEPPYTLLDFFPKDSIMMIDESHVTMPQIRGMYNGDRARKQMLIDYGFRLPSALDNRPLTLPEFEEHVNEIMYVSATPGPYEAEQTDIQVDQIIRPTGLLDPNIEVRPIMGQIDDLVGEINDRIEKNERVFITTLTKKMSEDLTDYLKELGIKVRYLHSDIKTLERTEIIRDLRLGKFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRSERSLIQTIGRASRNEHGQVLLYADKITDSMRHAIDETKRRRTIQEDYNTAHNITPKTIIKPIRDAISMVQSVEHPEEIKMTNEIDLENMSKAEKLEMVERLSEQMRLAAKKLDFEQAATLRDTILELKSEID
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_CUTAK
Sequence: MLIAQRPTLTEESISEFRSKFVIEPLEPGFGYTIGNSLRRTLLSSIPGASVTSIKIEGVQHEFSTIEGCVEDVTEIILNLKGLVLSSEEDEPVAMYLRKTGAGEITAADINPPAGVTIHNPELHIATLNDDGRFEMELIVERGRGYVSSALNDDPNAEIGRIAVDSIYSPVLKVTYKVEATRVEQRTDFDKLVVDVETKPSILPRDAIASAGKTLVELFGLTRELNVEAEGIEIGSGPVDEEYAESLGTPVEELNLTVRSYNCLKREGIHTVGELVSRSEQDLLAIRNFGSKSIDEVKEKLTELGLALKDSAPGFDPLAAAEAYDEANDDDYAETEQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: PROL1_HUMAN
Sequence: MKLTFFLGLLALISCFTPSESQRFSRRPYLPGQLPPPPLYRPRWVPPSPPPPYDSRLNSPLSLPFVPGRVPPSSFSRFSQAVILSQLFPLESIRQPRLFPGYPNLHFPLRPYYVGPIRILKPPFPPIPFFLAIYLPISNPEPQINITTADTTITTNPPTTATATTSTSTKPTMTISSSTVPISSTPEPATSISAATPAASTENTTQILANRPHTVLLNATVQVTTSNQTILSSPAFKSFWQKLFAIFG
What is the function of this protein?
Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N.  Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively.  Inhibits the breakdown of Ala-pNA by aminopeptidase N in vitro with an IC(50) of 65 uM.  Has a potent analgesic effect when administered to rats by intravenous injection.
What are the official names of this protein?
Opiorphin prepropeptide, Basic proline-rich lacrimal protein, Proline-rich protein 1, PRL1.
What is the protein family that this protein belongs to?
Belongs to the PROL1/PROL3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_STRA5
Sequence: MAKKTKKAEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGERAEQKVQVMSSGSLALDIALGAGGYPKGRIVEIYGPESSGKTTVALHAVAQAQKEGGIAAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVAALVPRAEIDGDIGDSHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGNPETTPGGRALKFYSSVRLDVRGNTQIKGTGEHKDHNVGKETKIKVVKNKVAPPFREAFVEIMYGEGISRTGELIKIASDLDIIQKAGAWYSYNGEKIGQGSENAKKYLADNPAIFDEIDHKVRVHFGMTEDDSPVQSELVEEKNEADDLVLDLDNAIEIEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPRTL_STRT2
Sequence: MNLTDYVKTVSIEDFGWKFKHQALWNKRLRTTGGRFFPKDGHLDFNPKLYEEHGLETFRKIVRHELCHYHLYFQGKGCKHGDRDFKDLLARVDGLRYAPKMRNQAENYFLYQCQSCGHTYRRKRRVNTQKFGCGLCQGKLIFLNQS
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPLD_STAAM
Sequence: MNKNIIIKSIAALTILTSITGVGTTVVDGIQQTAKAENSVKLITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGESTRSFAVYFSPEIKKFIADNLDK
What are the official names of this protein?
Serine protease SplD.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1B family.
What are the subcellular locations of this protein?
Secreted.
Protein: JIP5_NEUCR
Sequence: MLENLCTLPLSADLFTQVVHPSKPLLTVGLSNGRVETFRIPTNEDSDDDEDENSSITGGKGVIKSVWSTHRHKGSCRTLTYSTDGESLYSAGTDSIVKHFSPETGVVISKIGLPPVNSTSSQSDTPAILHTLSPQTLLLGTDSGSLYIFDLRENGSLNPKPVRKHVPHSDYISSLTPLPPSSESTSGFPKQWVSTGGATLAVTDLRHGIMATSEDQEDELLCSTVIPTGLGPKHMRNNAVLAVGTGGGVLTLWDRGAWDDQQERIYVAPGETKRDGESLDAIVRVPDELGWGKKAVVGVGDGTVKIVDLKRREVQTTFQHDEVEGVAALNFDYENRLISGGGRTVKVWAEAGSAQEDEEEEEEVVEADQGVKRPAGSDDSDDDDGSDSDSDRPKRERKKKRRKGNKKGKHGGPSVSFPGLD
What are the official names of this protein?
WD repeat-containing protein jip5.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR55 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: UREF_SPOPA
Sequence: METYIQESDISNEDDLKAFCDMYLRQNLASTDAIIAQEAYRLAKENDLQGLIRLENICHAIKLSPETRKGSMMMGRQFLQTVQPLNNSELFTIWCEKLKNKEIKSHYPVVYGIYTAMLGVDLRTSLETFLYSSITSLVQNGVRAIPLGQNSGVQTIFSLLPVIQETTSRVMTLDLEHLDNNSIGLEIASMKHEFLHSRLFIS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PCYA_MICAN
Sequence: MIAVTTPEILPLLHPLIGQLATAILSHWENYLDLSPFELPEGLGYVEGRLEGEKLIIENRCYQTPQFRKMHLELAKLGNGLDILHCVMFPRPEYPLPMFGCDIVSGKAGISAAIVDLSPTSGDKTLPSAYNQALAALPGADFAQARDLPPWGHIFSQYCLFIRPETAAEERQFLQRVTDFLTIHCKCARESQPLSGEEARIYLQGQRDYCSQQQKNDKTRRVLEKAFGWEWAERYMTGVLFDLPD
What is the function of this protein?
Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin.
What are the official names of this protein?
Phycocyanobilin:ferredoxin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the HY2 family.
Protein: UBIE_SHEFN
Sequence: MSEGEPKNTHFGYKTVEADKKADLVADVFHSVAAKYDIMNDVMSFGVHRFWKRHTIEVAAARPGMKVLDLAGGTGDLTAKFSHLVGDRGQVVLADINDSMLKVGRTKLRDKGIVNNVSYVQANAEALPFPDNHFDIITIAFGLRNVTDKDAALRSMQRVLKPGGKLLVLEFSTPKHELMRKVYDMYSFKVLPKMGALITKDADSYEYLAESIRMHPDQETLKQMMVDAGFEQVDYTNMTDGVVALHRGYKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: PDXJ_RHOP2
Sequence: MPKSSPLRLGVNIDHIATVRNARGGRHPDPVRAALTAIEAGADGITAHLREDRRHIRDNDMERLKAEISKPLNFEMAATPDMVRIALGVKPHAVCLVPERREELTTEGGLDVVGQRDSLAPSIARFNDAGIRVSLFIAADPAQIEMAAKLKAPAIELHTGAWCDAITDDEPAKVAEEWRRIVAGAALAQSAGLEVHAGHGLDYATAETIAALPQIVELNIGFYMIGEALFVGLGETVKAMRSAMDRGRARVIAA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.