PharMolix/UniProtQA huggingface dataset:
Protein: PYRH_BDEBA
Sequence: MKEPVYKRILLKLSGEALAGKQGTGINTATITQIAQDVAAAYKAGVQIGLVIGGGNIYRGVAASAEGMDRASADYMGMLATCINALALQDALEKQGVPTRVQTAIEMAEIAEPYIRRRAIRHLEKNRLVIFGAGTGNPFFTTDTAASLRAMEINAQVIMKATKVDGIYDKDPAKHADAKKFDKISYIDVLNRGLQVMDSTAISMCMDNKLPIITFDLTVPGNILKAVQGETIGTLVH
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ICP22_HHV11
Sequence: MADISPGAFAPCVKARRPALRSPPLGTRKRKRPSRPLSSESEVESDTALESEVESETASDSTESGDQDEAPRIGGRRAPRRLGGRFFLDMSAESTTGTETDASVSDDPDDTSDWSYDDIPPRPKRARVNLRLTSSPDRRDGVIFPKMGRVRSTRETQPRAPTPSAPSPNAMLRRSVRQAQRRSSARWTPDLGYMRQCINQLFRVLRVARDPHGSANRLRHLIRDCYLMGYCRARLAPRTWCRLLQVSGGTWGMHLRNTIREVEARFDATAEPVCKLPCLETRRYGPECDLSNLEIHLSATSDDEISDATDLEAAGSDHTLASQSDTEDAPSPVTLETPEPRGSLAVRLEDEFGEFDWTPQEGSQPWLSAVVADTSSVERPGPSDSGAGRAAEDRKCLDGCRKMRFSTACPYPCSDTFLRP
What is the function of this protein?
Transcriptional regulator that interacts with cellular elongation regulators to inhibit host cell transcription and promote viral gene expression in productive infection, mainly by mediating changes on the host RNA polymerase II (PubMed:17344289, PubMed:28611249, PubMed:34696162).  One change, which is UL13 independent, is the rapid loss of Pol II forms bearing Ser-2 phosphorylation in the heptapeptides of the CTD leading to unproductive elongation of pol II (PubMed:17344289, PubMed:25233083).  A second change, which is UL13 dependent, is the appearance of an intermediate form of Pol II that differs from the normal hypo- and hyperphosphorylated forms.  These Pol II modifications immediately inhibit host genome transcription, leading to cell cycle deregulation and loss of efficient antiviral response (Probable).  In opposition to its role in productive infection, inhibits transcription elongation of early viral genes, which can be beneficial because it reduces antisense and intergenic transcription (PubMed:35019725, PubMed:23029222).  This regulatory function directly or indirectly helps to retain Pol activity on the viral genome later in infection (PubMed:35019725).  The viral protein VP16 overcomes transcriptional inhibition by ICP22 to promote transcription of IE genes (PubMed:34696162, PubMed:23029222).  Recruits FACT complexes to the viral genome by interacting with the FACT complex, which could allow Pol II to cross the nucleosome barrier on the viral genome and achieve efficient viral transcription elongation late in viral infection and ultimately infectious virion production (Probable).  Plays a role in virion primary envelopment, possibly by interacting with and regulating UL31 and UL34 (PubMed:24741100).  Essential for the recruitment of Hsc70 into virus induced chaperone enriched (VICE) domains in infected cells (PubMed:20032172).  May function as a co-chaperone (J protein-like), functionning together with Hsc70 to recognize and manage aggregated and misfolded proteins (PubMed:31748398).
What are the official names of this protein?
Transcriptional regulator ICP22, Immediate-early protein IE68, Infected cell protein 22, ICP22.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae ICP22 family.
What are the subcellular locations of this protein?
Host nucleus. Note=Localizes in small nuclear bodies early in infection then moves to a more diffuse distribution in viral compartments as infection progresses.
Protein: 1A1D_THEMA
Sequence: MRIDLSLKPTPVQFLKRLSEKYGFNIYVKRDDLTELVGSGNKIRKLEYLLWEALKKGATTVFTCGGLQSNHARATAYVSRRYGLKPVLFLRKGEKVLNGNLLLDILLGAEIVEVSPEEYERIDEIFDVHKKMREKKGEKVYVIPEGGSNSLGAFGYFNAVLEMKDQLNLESFDAIVCAVGSGGTIAGLSAGISFLEYHVPVVGVNVTTKNSDYFVGKVKRIISGMEEYGLRVNETVFEVVDDYRGPGYAIPSSEDVEILKEVASIEGIILDPVYTAKAFRGMIEMFRNSEKNVLFIHTGGIFGLFAQSRRLV
What are the official names of this protein?
Putative 1-aminocyclopropane-1-carboxylate deaminase, ACC deaminase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: Y7975_HAEIE
Sequence: MLISHSDLNQQLKSAGIGFNATELHGFLSGLLCGGLKDQSWLPLLYQFSNDNHAYPTALVQPVTELYEKISQTLSDVEGFTFGLGLTEDENVFAQADSLSDWANQFLLGLGLAQPELAKEKGEIGEAVDDLQDICQLGYNEDDNEEELAEALEEIIEYVRTIAMLFYSHFNEGEIESKPVLH
What are the official names of this protein?
UPF0149 protein CGSHiEE_07975.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: RS8_SPOFR
Sequence: MGISRDHWHKRRATGGKRAPIRKKRKYELGRPAANTKLGPQRIHLVRSRGGNTKYRALRLDTGNFSWGSECSTRKSRIIDVVYNASNNELVRTKTLVKNAIVVVDATPFRQWYESHYLLPLGRKKGAKLTEAEDAIINKKRSQKTAKKYLARQRLSKVESALEEQFHTGRLLACVASRPGQCGRADGYILEGKELEFYLRKIKSKRAK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
40S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: MED21_EMENI
Sequence: MADILTQLQTCLDQLATQFYATIGYLTTYHDNSPAIPPDNPTSAPALAKIQKNSTNPPIPAGAAAILNASQGSPSGAATGAVTPGPPAPNASAGSGAGEAGAARQEEGLPPRPDSPRTFTARQRELARDLVIKEQQIEYLISVLPGIGSSEAEQERRIRKLEEELRAVEEEREKRVRELRVLRRRVEEVLGAVEGGIYGGSSY
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 21, Mediator complex subunit 21.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 21 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YKG6_YEAST
Sequence: MAWEGTYERLFFLALGSSYHVPSLANNIMNFLEGARLYKKNTTYVATLIYEFIILNDASMTPDVKCFWLPVKLPHFLLLSELYSIIEKYKLAKVYYNRGTYDVHTVSANSLVISGSMPTGIIIGSSSPLDYVGVQVNRQLEMDLPIE
What are the official names of this protein?
Putative uncharacterized protein YKL066W.
Protein: RS4A_BDEBA
Sequence: MSCINESVCKLCRRENVKLFLKGDRCYTDKCSFERRPYPPGQHGQSRLKFSEFALQLREKQKAKRYYGVSEKQFVKYVGEANRAKELTGHALLKFLETRLDNVVYTLGYANSRREARQLVKHNHFLLNGKRANIPSILVNKGDVIQVAESSREMAKIQSAIQAVARRSVPAWLEADHAKFTGTVKDLPNREDVAVAVEENMIVEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4 A.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: BACS3_HALMA
Sequence: MAQEIVWYGAGAGAFFVSAVVFVWFAATRGNIRSSFYYLPPIHTSVAGAAYVAMALIAGGQLGDTVSITTLRFADWIVSTPIITYYLARLAGVDTQTRRLAVAANVVMIGVGYGFVSMSGSLRWIAFAVSTVAFIGLLYLYIKTFARKINAATASVRSLFQSLRDLTVVTWSLYPVVYFLGPLGTGIIQAPDLNFLVAVLDTIAKVGFMSILLVRYNSVETFVDSWSVAPAK
What is the function of this protein?
Sensory rhodopsin.  Associates with an unusual transducer lacking a methyl-accepting transducer domain found in all other photosensory transducers.  The chromophore is all-trans-retinal in the dark.
What are the official names of this protein?
Sensory rhodopsin III, HmSRIII, Opsin, Sensory-like rhodopsin, HmSMR.
What is the protein family that this protein belongs to?
Belongs to the archaeal/bacterial/fungal opsin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: LYSC1_HORSE
Sequence: KVFSKCELAHKLKAQEMDGFGGYSLANWVCMAEYESNFNTRAFNGKNANGSSDYGLFQLNNKWWCKDNKRSSSNACNIMCSKLLDENIDDDISCAKRVVRDPKGMSAWKAWVKHCKDKDLSEYLASCNL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, milk isozyme, 1,4-beta-N-acetylmuramidase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
Protein: INO1_MOUSE
Sequence: MEPAAEILVDSPDVVYSPETIEARYEYRTTRVSREGGVLRVQPRATRFTFRTARQVPRLGVMLVGWGGNNGSTLTAAVLANRLRLTWPTRTGRKEANYYGSLTQAGTVNLGLDENGREVFVPFSALLPMVAPNDLVFDGWDISSLNLAEAMRRAQVLDCGLQEQLWPHMESLRPRPSVYIPEFIAANQTARADNLIPGTRAQQLEQIRKDIRDFRSSAGLDKVIVLWTANTERFCEVVPGRNDTAENLLHTIQLGLEVSPSTLFAVASILEDCAFLNGSPQNTLVPGALELASQRHVFVGGDDFKSGQTKVKSVLVDFLIGSGLKTMSIVSYNHLGNNDGQNLSAPLQFRSKEVTKSSVVDDMVHSNHVLYAPGERPDHCVVIKYVPYVGDSKRALDEYTSELMLGGTNTLVLHNTCEDSLLAAPIMLDLVLLTELCQRVSFCTDSDPEPQGFHTVLSLLSFLFKAPLVPPGSPVVNALFRQRSCIENIFRACVGLPPQNHMLLEHKMERPGPGIKPGEVVATSPLPCKKEPTPATNGCTGDANGHPQAPTPKLSTA
What is the function of this protein?
Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner.  Rate-limiting enzyme in the synthesis of all inositol-containing compounds (By similarity).
What are the official names of this protein?
Inositol-3-phosphate synthase 1, IPS 1, Myo-inositol 1-phosphate synthase, MI-1-P synthase, MIP synthase.
What is the protein family that this protein belongs to?
Belongs to the myo-inositol 1-phosphate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RND_ECOLI
Sequence: MNYQMITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFDGEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQILAAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITAKLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLADWRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVEKAQTLPEDALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLLNWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ
What is the function of this protein?
Exonuclease involved in the 3' processing of various precursor tRNAs.  Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides.
What are the official names of this protein?
Ribonuclease D, RNase D.
What is the protein family that this protein belongs to?
Belongs to the RNase D family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGA_POLAQ
Sequence: MLTFQQIILKLQDYWDQQGCALLQPIDLEVGAGTSHTATFLRAIGPEPWKAAYVQPSRRPKDGRYGENPNRLQHYYQYQVVLKPAPENILELYLGSLATLGLDLKQNDIRFVEDDWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLDCKPVLGEITYGIERLAMYIQNCSNVYDLVWADGISYGDVYHQNEVEQSCYNFEHSNTDLLFANFTNFESEAKRLMEVPLALPAYEMVLKAAHTFNLLDARGAISVTERAAYIGRIRNLSRAVAQAYFESREKLGFPMCQRQVKA
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FCG3A_CAVPO
Sequence: MWHLLPPSALLLLISSVTKAADPSKAVVLLDPPWVRVLTDDNVTLTCQGAYPPENNNTRWFHNGTHIVGSQAPSYLISGIKVENSGKYQCQTDLSPLSDSVQLQVHADWLVLQTSKWVFQKGESIRLRCHSWKNKRLYKVTYLQNGKPKKFFHNNSEFHIPEATVNHTGSYYCRGLIGHNNKSSGIVAITFQADFAGPSIAPLFPLWQQIAFCLMMGLLFAVDTGLYFFVRRDLRRSMVHKEEYNFKWSQAQDK
What is the function of this protein?
Receptor for the invariable Fc fragment of immunoglobulin gamma (IgG) (Ref. 3).  Binds with intermediate affinity to both IgG2a and IgG2b.  Can bind to IgG2a and IgG2b monomers.  Does not display binding to IgG1 or IgG3 (By similarity).  Recognizes neutralizing virus-specific IgGs displayed on the cell surface of infected cells and triggers antibody-dependent cellular cytotoxicity (ADCC).  Confers protection to lethal influenza virus infection (By similarity).  On splenic dendritic cells, uptakes antigen immune complexes and efficiently divert them into MHC class I and II antigen presentation pathways to provide for superior priming of CD4-positive and CD8-positive T cell immune responses (By similarity).  Mediates neutrophil activation by IgG complexes redundantly with FCGR2A (By similarity).  Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (By similarity).  Also acts as a receptor for the Fc region of immunoglobulin epsilon (IgE).  Binds with low affinity to both the a and b allotypes of IgE.  Has also been shown to bind to IgE allotype a only but not to allotype b.  Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes.  Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of pro-inflammatory cytokines and the late phase of cutaneous allergic reactions (By similarity).  Mediates enhanced ADCC in response to afucosylated IgGs (PubMed:34485821).
What are the official names of this protein?
Low affinity immunoglobulin gamma Fc region receptor III-A, IgG Fc receptor III-A, CD16-2, FcgammaRIV.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: CARA_SYNY3
Sequence: MPIAAAKPALLVLADGTPYPGWSFGADGTTVGEVVFNTGMTGYQEVMTDPSYCGQIVTFTYPELGNTGVNAEDEESIHPHVKGVVARNITRRPSNWRSTQSLPDYLVEHKIIGIYGIDTRALTRKLRSIGAMNGGISTEILEPEALLHHIQAAPSMAGLNLVKEVTTHEVYEWTDSTNDHWQFGPVAEQQGQPPLTVVALDFGVKRNILRRLASYGCRVIVVPASTSAAEILQYNPDGIFLSNGPGDPSAVEEGIVTTKELLAAKKPMFGICMGHQVLGLSLGAETFKLKFGHRGLNQPCGLEQQVEITSQNHGFAVTEGSLAEEVEITHFNLNDKTVAGLRHKELPFFSVQYHPEASPGPHDADYLFEKFVKLMRQQKAEVAG
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: MOAC_MACCJ
Sequence: MNQLTHFNEQGRAKMVDVSDKSVSTRTAVAKSSIKVNEVIHDQIINHKNKKGDVLGVAQVAGIMAAKNTSQIIPMCHPLNLSGIDISFEWDISDGYEIFITCTVKTTGQTGVEMEALTGASATALTIYDMTKAVDKGMIIGPTYLEHKSGGKNGDFNR
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: ARGC_NITEU
Sequence: MINAGIVGGTGYTGVELLRILVQHPKVKLKVITSRQEAGTGVDELFSSLRGQIALKFSDPAKVDFSKCDVVFFATPNGIAMQQAKALLDSGIKVIDLAADFRIKDVAEWEKWYGMTHAAPELVAEAVYGLPEVNREKIRDARLIANPGCYPTAVQLGFIPLIEAGAVDADHLIADTKSGVSGAGRKAEIHTLYAEASDNFKSYAVPGHRHLPEIRQGLSERSNGPIGLTFVPHLTPMIRGIHATLYARLTRDVDLQTLYENRYANEPFVDVLPAGSHPETRSVRGSNFCRIAVHRPGNGDTAVILSVTDNLVKGAAGQAVQNMNIMYGLPETTGIRHVPLLP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQHD_ECOLI
Sequence: MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDKQAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR
What is the function of this protein?
NADP-dependent ADH activity.
What are the official names of this protein?
Alcohol dehydrogenase YqhD.
What is the protein family that this protein belongs to?
Belongs to the iron-containing alcohol dehydrogenase family.
Protein: S620A_MOUSE
Sequence: MEKARPQWGHPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVCPLNSNHTGYDEECEKASSTQYFWYRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTASMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSIINSSTSIFASIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTVSNLEEVKNYLASTYPNKYSEVFPHIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAAILTPLTDSKVISSYLPKEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAATLSLLLIVLVETIAVCYVYGLKRFESDLRAMTGRTLSWYWKVMWAFVSPLLIVGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALAVIGLLVASSTMCIPLVALGTFIRNRLKRGGSAPVA
What is the function of this protein?
Mediates the Na(+)- and Cl(-)-dependent uptake of imino acids such as L-proline, N-methyl-L-proline and pipecolate as well as N-methylated amino acids (PubMed:15689184).  Also transports glycine, regulates proline and glycine homeostasis in the brain playing a role in the modulation of NMDAR currents (PubMed:33428810).
What are the official names of this protein?
Sodium- and chloride-dependent transporter XTRP3A, IMINO-B, Solute carrier family 6 member 20A, X transporter protein 3 similar 1.
What is the protein family that this protein belongs to?
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A20 subfamily.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Note=Located in the apical brush border membrane of kidney proximal tubule cells and in the apical membrane of enterocytes lining the intestinal villi.
Protein: OXDC_BACSU
Sequence: MKKQNDIPQPIRGDKGATVKIPRNIERDRQNPDMLVPPETDHGTVSNMKFSFSDTHNRLEKGGYAREVTVRELPISENLASVNMRLKPGAIRELHWHKEAEWAYMIYGSARVTIVDEKGRSFIDDVGEGDLWYFPSGLPHSIQALEEGAEFLLVFDDGSFSENSTFQLTDWLAHTPKEVIAANFGVTKEEISNLPGKEKYIFENQLPGSLKDDIVEGPNGEVPYPFTYRLLEQEPIESEGGKVYIADSTNFKVSKTIASALVTVEPGAMRELHWHPNTHEWQYYISGKARMTVFASDGHARTFNYQAGDVGYVPFAMGHYVENIGDEPLVFLEIFKDDHYADVSLNQWLAMLPETFVQAHLDLGKDFTDVLSKEKHPVVKKKCSK
What is the function of this protein?
Converts oxalate to formate and CO(2) in an O(2)-dependent reaction.  Can also catalyze minor side reactions: oxalate oxidation to produce H(2)O(2), and oxalate-dependent, H(2)O(2)-independent dye oxidations.
What are the official names of this protein?
Oxalate decarboxylase OxdC.
What is the protein family that this protein belongs to?
To B.subtilis OxdD.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OMPB2_NEIMI
Sequence: MKKSLIALTLAALPVAAMADVTLYGTIKAGVETSRSVAHNGAQAASVETGTGIVDLGSKIGFKGQEDLGNGLKAIWQVEQKASIAGTDSGWGNRQSFIGLKGGFGKLRVGRLNSVLKDTGDINPWDSKSDYLGVNKIAEPEARLISVRYDSPEFAGLSGSVQYALNDNAGRHNSESYHAGFNYKNGGFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASVAVQQQDAKLVEENYSHNSQTEVAATLAYRFGNVTPRVSYAHGFKGSFDATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF
What is the function of this protein?
Serves as a slightly cation selective porin.
What are the official names of this protein?
Major outer membrane protein P.IB, PIB, Protein IB, Class 3 protein, Porin.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: LEUC1_RUBXD
Sequence: MEKKKPRTLVEKIWERHVVRRAEGEPDLLYVDLHMVHEVTSPQAFEALRLAGRRVRRPDLTVATMDHNVPTTDVRLGVRDRVSARQMEALRKNCEEFGIQLHEWGSPGQGIVHVIGPEMGLTQPGMVIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTIPQRRPKTMAITVEGEAPPDVTAKDIMLGILHRIGTGGGVGHAIEYRGEAIRNLSMEGRMTICNMTIEGGGRAGMVAPDEKTYSYIEGRPHAPKGRAWEEALEYWQSLPTDEGATFDKEVVIDAAELVPYVSWGTTPAQTVPLDGEVPEPQNEGHERALRYMGLRPGTPIREIEVDTVFIGSCTNARIEDLRAAARVLEGHKVKEGIRAMVVPGSMRVKKQAEEEGLDEIFKKAGFEWRNAGCSMCLGMNPDILSPGERCASTSNRNFEGRQGKGGRTHLVSPVVAAATAVMGRFASPSELGVPVEVG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit 1, Alpha-IPM isomerase 1, IPMI 1, Isopropylmalate isomerase 1.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RS15_NOSP7
Sequence: MALTQLRKQEIISNYQVHETDTGSADVQVAMLTERINRLSEHLQANKKDHSSRRGLLKLIGQRKRLLAYISQESREKYQALIARLGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: RUTF_ECOLI
Sequence: MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPAFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQTGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHTTPYGLVWFDRSYHALMRPAC
What is the function of this protein?
Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway.  In vitro, the flavin reductase Fre can substitute for the function of RutF, however, RutF is required for uracil utilization in vivo.
What are the official names of this protein?
FMN reductase (NADH) RutF, FMN reductase, NADH-flavin reductase RutF, NADH:flavin oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family. RutF subfamily.
Protein: MNMG_HALHL
Sequence: MNTNRFDVIVIGGGHAGTEAAAAAARLGRSTLLITHNLETIGALSCNPAIGGIGKGHLVREIDALGGVMGRLADASAIHARVLNQRKGPAVRATRIQADRPTYARAARRALDALPGLALLQDAAEELLVADQRCYGVRTESGATLHADAVVVTAGTFLAGQIHIGHVQHSAGRAGDPAADRLSASLRDLGLAVHRLKTGTPPRIDRRTVAVEQLDAQHGDTPRPLFSPFRPPEAPLPEAACLISWTTPETHRIIRDALDHSPMYSGAIQSSGPRYCPSIEDKVVRFADRDHHQVFLEPEGLDATELYPNGVSTGLPFTVQEALIRSMPGLEAARITRPGYAIEYDYLDPRGLTPWLESATIAGLYLAGQINGTTGYEEAAAQGLIAGLNAARVSAGEDPWFPTREEAYIGVLIDDLVTTGVTEPYRMFTSRAEHRLRLRDDNAEDRLTEVGRRLGSVGDDQWTRFARYRDALNAERARLNGTRVHPGRLTASQQARLGGALRRDQTLFDLLRRPELSYDDVRFIGGLEEADLPVRAVQQLEIEARYDGYVERQELENQRHQRYAQVRLPEALDYAAIDGLSTEVRERLTRMRPATVGQAARLPGVTPAAISLLLIHLRRRGWLRTPTGGEDAA
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG_CHRVO
Sequence: MFDVLTYLFEQYSDPAAFGDRSALTRQLNAVGFDDDDIGEALDWLDSVGEASVEPYLGADEGSGLRIYADSELEYLSPDVRGLIQFLEDNGALSPAQREMVIDRLLELDPEDLDIDTAKLLVLMVLWAQQAELPILLGEALLEAVHGEPTMQ
What are the official names of this protein?
Protein Smg homolog.
What is the protein family that this protein belongs to?
Belongs to the Smg family.
Protein: RS10_AERPE
Sequence: MAFKLRIWLWSTNVRSLENVVEQIRNIANKTGIRMRGPVPLPVKRLEVPVFRLPHGEGSKYWEHWEMKVHKRLIDLEADERVLRHLMRIKVPEDVYIEIKQMTG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SP5G_BACC2
Sequence: MEVTDVRLRRVNTEGRMRAIASITLDHEFVVHDIRVIDGNNGLFVAMPSKRTPDGEFRDIAHPINSGTRSKIQDAVLTEYHRLGELEEVEFEEAGAS
What is the function of this protein?
Essential for sporulation.  Interferes with or is a negative regulator of the pathway leading to asymmetric septation.
What are the official names of this protein?
Putative septation protein SpoVG, Stage V sporulation protein G.
What is the protein family that this protein belongs to?
Belongs to the SpoVG family.