PharMolix/UniProtQA huggingface dataset:
Protein: G3BP1_BOVIN
Sequence: MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFITEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQTVSNDLEEHLEEPVAEPEPEPEPEPEQEPVSEVQEEKSEPVLEETAPEDVQKSSSPAPADIAQTVQEDLRTFSWASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPLQRPQRDQRVREQRINVPPQRGPRPVREAGEQGDVEPRRIVRHPDSHQLFIGNLPHEVDKSELKDFFQNYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGMVQKPGFGVGRSIAPRQ
What is the function of this protein?
ATP- and magnesium-dependent helicase that plays an essential role in innate immunity.  Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS.  Enhances also RIGI-induced type I interferon production probably by helping RIGI at sensing pathogenic RNA.  In addition, plays an essential role in stress granule formation.  Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends.  Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency.  Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.  Phosphorylation-dependent sequence-specific endoribonuclease in vitro.  Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR.
What are the official names of this protein?
Ras GTPase-activating protein-binding protein 1, G3BP-1, ATP-dependent DNA/RNA helicase G3BP.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Perikaryon. Cytoplasm, Stress granule. Nucleus. Note=Cytoplasmic in proliferating cells, can be recruited to the plasma membrane in exponentially growing cells. Cytosolic and partially nuclear in resting cells. Recruited to stress granules in response to arsenite treatment. The unphosphorylated form is recruited to stress granules. HRAS signaling contributes to this process by regulating G3BP dephosphorylation.
Protein: RELX_SQUAC
Sequence: QSFKNAEPGIKLCGREFIRAVIYTCGGSRWEGSPGMSSKCCTYGCTRKDISILC
What is the function of this protein?
The function of relaxin in an oviparous species is not yet known.
What are the official names of this protein?
Relaxin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARSA_BOVIN
Sequence: MEALWTLTLALAAGLAAASPPNILLIFADDLGYGDLGSYGHPSSTTPNLDQLAAGGLRFTDFYVPVSLCTPSRAALLTGRLPVRMGLYPGVLEPSSRGGLPLDEVTLAEVLAAQGYLTGIAGKWHLGVGPEGAFLPPHHGFHRFLGIPYSHDQGPCQNLTCFPPATPCEGICDQGLVPIPLLANLSVEAQPPWLPGLEARYVAFARDLMTDAQHQGRPFFLYYASHHTHYPQFSGQSFPGHSGRGPFGDSLMELDAAVGALMTAVGDLGLLGETLVFFTADNGPETMRMSHGGCSGLLRCGKGTTFEGGVREPALAFWPGHIAPGVTHELASSLDLLPTLAALAGAQLPNITLDGVDLSPLLLGTGKSPRHTLFFYSAYPDEVRGVFAVRSGKYKAHFFTQGSVHSDTTADPACHASNPLTAHEPPLLFDLSEDPGENYNLLDSVDEVAPEALQAVKQLELLKAQFDAAMTFGPSQMAQGEDPTLQVCCQPSCTPRPSCCHCPEFQP
What is the function of this protein?
Hydrolyzes cerebroside sulfate.
What are the official names of this protein?
Arylsulfatase A, ASA, Cerebroside-sulfatase.
What is the protein family that this protein belongs to?
Belongs to the sulfatase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Lysosome.
Protein: RSBP_BACSU
Sequence: MDKQLNDAPCGFLALSEEGSIIAANRTLIKILDYEPEQVIGQHMNMMLTIPAQLFCQLYFFPLLKLEHHIEEIYISLKARDGEEIPVLINAIARHDSGASVFDCVLIPMRKRNEYENELLIARNEAQEALLAKQKANAELEIALETLKAKQEELLEINKQNQQFKLNTKRELELARKIQKNSLTEPIVNDQVQIDSYYNASSELSGDLYGYYQIDEHRYGIIILDVMGHGISSALITMSLHPLFQRQITQGLSPVKVMKELDRHLHSLFQNDEEARHYCTAIYLEIDIARQRIDYVNAGHPPALWQDDSGTQHLLHATSPPIGMFEDLEFQSSSLSYTEDGRLLLYTDGVMDPTASCYLFDLLKDHPDSPIADLKEKILTSLQHQKEAHHKSDDECFILVDVK
What is the function of this protein?
Positive regulator of sigma-B activity.  Dephosphorylates RsbV in response to energy stress.
What are the official names of this protein?
Phosphoserine phosphatase RsbP.
Protein: RS2_CORJK
Sequence: MAVVTMRELLDAGVHFGHQTRRWNPKMKRFIFTDRNGIYIIDLQQTLTYIDEAYEFVKETVAHGGNILYVGTKKQAQEAVANEAERVGMPYVNHRWLGGMLTNFQTVAKRLHRLKELQAMDAAEDGYKGRTKKEVLMLTRERNKLERVLGGIADMTKTPSALWIVDTNKEHIAVSEAQKLNIPVVAILDTNCDPDVVDYPIPGNDDAIRSANLLTSIISSAVEAGRQARAERQEAAAKEAAGDADKAPAEAERTEAPAEEAPAEAQSEAKAEGNTEA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: PYRB_MYCBP
Sequence: MTPRHLLTAADLSRDDATAILDDADRFAQALVGRDIKKLPTLRGRTVVTMFYENSTRTRVSFEVAGKWMSADVINVSAAGSSVGKGESLRDTALTLRAAGADALIIRHPASGAAHLLAQWTGAHNDGPAVINAGDGTHEHPTQALLDALTIRQRLGGIEGRRIVIVGDILHSRVARSNVMLLDTLGAEVVLVAPPTLLPVGVTGWPATVSHDFDAELPAADAVLMLRVQAERMNGGFFPSVREYSVRYGLTERRQAMLPGHAVVLHPGPMVRGMEITSSVADSSQSAVLQQVSNGVQVRMAVLFHVLVGAQDAGKEGAA
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: NHEJ1_HUMAN
Sequence: MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKELNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWNFHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS
What is the function of this protein?
DNA repair protein involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination (PubMed:16439204, PubMed:16439205, PubMed:17717001, PubMed:17317666, PubMed:17470781, PubMed:18644470, PubMed:20558749, PubMed:26100018, PubMed:18158905).  Plays a key role in NHEJ by promoting the ligation of various mismatched and non-cohesive ends (PubMed:17717001, PubMed:17470781, PubMed:19056826).  Together with PAXX, collaborates with DNA polymerase lambda (POLL) to promote joining of non-cohesive DNA ends (PubMed:30250067, PubMed:25670504).  May act in concert with XRCC5-XRCC6 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are non-complementary or partially complementary (PubMed:16439204, PubMed:16439205, PubMed:17317666, PubMed:17470781).  Associates with XRCC4 to form alternating helical filaments that bridge DNA and act like a bandage, holding together the broken DNA until it is repaired (PubMed:22228831, PubMed:26100018, PubMed:28500754, PubMed:27437582, PubMed:21775435, PubMed:22287571, PubMed:21768349).  The XRCC4-NHEJ1/XLF subcomplex binds to the DNA fragments of a DSB in a highly diffusive manner and robustly bridges two independent DNA molecules, holding the broken DNA fragments in close proximity to one other (PubMed:28500754, PubMed:27437582).  The mobility of the bridges ensures that the ends remain accessible for further processing by other repair factors (PubMed:27437582).  Binds DNA in a length-dependent manner (PubMed:17317666, PubMed:18158905).
What are the official names of this protein?
Non-homologous end-joining factor 1, Protein cernunnos, XRCC4-like factor.
What is the protein family that this protein belongs to?
Belongs to the XRCC4-XLF family. XLF subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to site of double-strand breaks; recruitment is dependent on XRCC5-XRCC6 (Ku) heterodimer.
Protein: NUOI_BUCBP
Sequence: MILFKFFLACFSQIKSVWLTFINIFSKRETRMYPEESLSLSSRYRGRIILSRNSFGKERCVACGLCSVVCPVSCISLKKSTLKNNKWYPKFFRINLSRCIFCGLCEEACPTLAIQLISDVELSEYKRQDLVYEKDDLLISGQGKYLDYDFYKFSGVEVGTKNKGELDFESHPIDVKTLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: ROT_STAAN
Sequence: MHKLAHTSFGIVGMFVNTCMVAKYVIINWEMFSMKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILLTLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQQEKVELLNFISDAIASRATAMQNSLNAIIAV
What is the function of this protein?
Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence.  Also, modulates the expression of genes not previously implicated in pathogenesis (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator rot, Repressor of toxins.
What is the protein family that this protein belongs to?
Belongs to the rot family.
Protein: RL30_LACPL
Sequence: MAQLKITLVRSAAHRLPKQRKIVKELGLGRINSSVVKPDDAATRGQIFHIAHLVDVEIIK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RS6_CLOAB
Sequence: MNKYETLFILNPSLDEEGINTNVEKFKSVITNGGGEVENVDLWGKRKLAYEIDKVNEGIYVLVNFQSDAQLPKELDRVFRISDSIIRHLIISLEK
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NORR_ECOSM
Sequence: MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSARARNLLQHYNFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEAFQRETIRQALAQNHHNWAASARMLETDVANLHRLAKRLGLKD
What is the function of this protein?
Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon.  Activation also requires sigma-54.
What are the official names of this protein?
Anaerobic nitric oxide reductase transcription regulator NorR.
Protein: YA95_SCHPO
Sequence: MIVHQQLPMSVNVASLDFLLIELVHTAKRLAEDRKKKSSSEKSIESDFQMLESIGFQVGRKITERLLLNRNRITETTDVMRFLCRELWPIVFRKPLDNLKTNRRGIFVLTDTYFYWFTKMTAMTGTEMAQITTPYFYFPSGFIRGVVYTFGYSAQVIAQCPNLPTCIFHVKFSPNPTQTSPGKPSTSESSQTDTSTRPANSQTPTTTRASSYTTLVSTSNQVSNEAEASAVETSANQAQNTEDATENEDRLPS
What are the official names of this protein?
Uncharacterized protein C13G6.05c.
What is the protein family that this protein belongs to?
Belongs to the TRAPP small subunits family. BET3 subfamily.
Protein: YIDC_MYCLE
Sequence: MSLLPFDFVSLDIVYYPVSWIMWVWYKLFAAVLGPSNFFAWALSVMFLVFTLRALLYKPFVRQIRTTRQMQELQPRIRALQRKYGKDRQRMALEMQKLQREHGFNPILGCLPMLAQIPVFLGLYHALRSFNRTTGGFGQPHMSVTENRMTGNYVFTPVDVGHFLDANLWGAPIGAYMTQRSGLDAFIDFSRPAVILVGIPMMVLAGVATYFNSRASIARQSAEAAENPQTALMNKIALYVFPFGVVVGGPFLPLAIILYWFSNNIWTFGQQHYVFSMIEKEDEAKKQKAIERRTANAPAPGSKPKYVSTTAPVSVNGFSKDTMISDDGAKLGSQEADSIDWVTETKTATTPADKPDCVGYNNNPTSHTRRSGQRTKRRKR
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins (By similarity).
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSBC_HUPLU
Sequence: MKILYSPRRFYPVETLFNGTLALGGRDQETTGFAWWAGNARLINLSGKLLGAHVAHGGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVVDIFPYFVSGVLHLISSAVLGFGGIYHAIIGPETLEESFPFFGYAWKDKNKMTTILGIHLILLGAGAFLSVLKALYFGGVYDTWAPGGGDVRKITNLTLNPSVVFGYLLKSPFGGEGWIVSVDNLEDIIGGHVWLGSICIFGGIWHISTKPFAWARRAFVWSGEAYLSYSLGALSVFGFIACCFAWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEIIFGGETMRFWDLRAPWLEPLRGPNGLDLSKLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVSGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSTTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YTJA_SALPB
Sequence: MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIVLFLVSLFMGRKRP
What are the official names of this protein?
UPF0391 membrane protein YtjA.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SAHH_ROSDO
Sequence: MTKDFIVKDIALAEFGRKELDIAETEMPGLMALRAEYGDSKPLAGARIVGSLHMTIQTAVLIETLVALGADVRWASCNIFSTQDHAAAAIAAGGTPVFAIKGQSLEEHWDYLDRSFMFEDGPNLILDDGGDATLYVLLGARAEAGEEIIPVPTSEEEEAIKAQIKKRMAASPGWFTKVRDQIKGVSEETTTGVHRLYDLVKQGQLPFPAINVNDSVTKSKFDNKYGCKESLVDGIRRATDTMMAGKVAVVMGYGDVGKGSAASLRGAGARVKVTEVDPICALQAAMDGFEVVLLEDVVGSADIFITTTGNKDVIRIEHMRAMKDMAIVGNIGHFDNEIQVAALKNHKWTNIKEQVDMIEMPNGNRLILLSEGRLLNLGNATGHPSFVMSASFTNQVLAQIELWTRADAYDNEVYILPKHLDEKVARLHLDRIGVKLTPLDPEQAAYIGVKPEGPFKPEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGK_PSEAB
Sequence: MTVLKMTDLDLKGKRVLIREDLNVPVKDGQVQSDARIKAALPTLKLALEKGAAVMVCSHLGRPTEGEFSAENSLKPVAEYLSKALGREVPLLADYLDGVEVKAGDLVLFENVRFNKGEKKNADELAQKYAALCDVFVMDAFGTAHRAEGSTHGVARFAKVAAAGPLLAAELDALGKALGNPARPMAAIVAGSKVSTKLDVLNSLAGICDQLIVGGGIANTFLAAAGHKVGKSLYEADLVETAKAIAAKVKVPLPVDVVVAKEFAESAVATVKAIAEVADDDMILDIGPQTAAQFAELLKTSKTILWNGPVGVFEFDQFGEGTRTLANAIADSAAFSIAGGGDTLAAIDKYGIAERISYISTGGGAFLEFVEGKVLPAVEILEQRAKG
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL21_DECAR
Sequence: MYAVIKTGGKQYRVSAGQKLKVEQIPADVGAEVTLDQILMVGEGESVKIGAPFLAGATVKCTVVSHGRHDKVKIFKMRRRKHYQKRQGHRQNYTELRIDTIAA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: GLGB_ECOUT
Sequence: MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWDGRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPIYRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNHTYRHHKAMHELDFDPYGFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGAVHSDEIASHGRQHSLSLTLPPLATIWLVREAE
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: BGLI_ASPFN
Sequence: MPRLDVEKTIEELSLGEKVALTAGIDFWHTASVPRLNIPTLRMSDGPNGVRGTRFFNGVPAACFPCATALGATWDTELLHEIGQLMGEESIAKGSHIILGPTINTQRSPLGGRGFESFAEDGVLSGLLAGYISKGIQEKGVAATLKHFVCNDQEHQRMAVDSIVTQRALREIYLLPFQLAMRICRTACVMTAYNKVNGTHVSQNKEIITDILRKEWGWDGLVMSDWFGTYSTSDAINAGLDLEMPGKTRWRGTALAHAVSSNEVAEFVMDERVRNVLNLVNFVDGLNIPENAPEKALNRPQDQALLRRAAAESVVLMKNEEDILPLKKEKSILVIGPNSKVAAYCGGGSASLDAYYTVNPFEGVSAQSKGEVKFSQGVYSHKDLPLLGPLLKTADGKTGFSFKVYNEHPSESNRELIEQLHLVSSSGFLMDYVNPKIKSLTYYVDMEGLFTPEEDGVYDFGVTVVGTGQLFIDGELVVDNTKNQRQGSAFFGSATVEEKGSKELKAGQTYKVLFQFGTAPTSDLDTRGVVVFGPGGFRFGASRRVGQEELISNAVKLASEAEQVVVFAGLTSEWETEGYDRDHMDLPPGSDEMISRVLDVNPNAVVVIQSGTPVTMPWANKTKALLHAWFGGNECGNGIADVLYGDVNPSGKLPITFPVRLQDNPSYVNFRSERGRVLYGEDVYVGYRYYEKVDLAPLFPFGHGLSYTTFTRSDLTLTTTPEKPQYEESGEPITATVTVTNTGKVAGAEIVQLWVAPPATEVNRPVRELKGFTKVFLQPGEQKKVEIVVEKKLATSWFDEMREKWASEKGEYGVLVTGTGEGVLKSSFKVEKTRYWLGL
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase I, Beta-D-glucoside glucohydrolase I, Cellobiase I, Gentiobiase I.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FDHE_CUPNH
Sequence: MNQHQATPGTLPSDEASRHFTPLIQPDLAGLYSRRAARLRALAEGHDLADYLRLAARVAEVQASLVAEADVSGPADARAIPQEGHWGALLDRLIERLAHDVPAPVAPHLAALRALPADARLGAAQALTEGRFDAVPAAIAPFLWAALSLQCASAARAAPVPDSGPAEHASCPVCGTAPVASLILIGDRQGMRYLHCALCESQWHMVRAKCTNCGEASELDYLSFDTAEATVRAESCGVCHGYLKVISLERDPPAEAVADDLASLALDDAVTAEGYQRTGFNPFALPG
What is the function of this protein?
Necessary for formate dehydrogenase activity.
What are the official names of this protein?
Protein FdhE homolog.
What is the protein family that this protein belongs to?
Belongs to the FdhE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SIK2_MOUSE
Sequence: MVMADGPRHLQRGPVRVGFYDIEGTLGKGNFAVVKLGRHRTTKTEVAIKIIDKSQLDAVNLEKIYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKFWQILSAVDYCHGRKVVHRDLKAENLLLDNNMNIKIADFGFGNFFKTGELLATWCGSPPYAAPEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILRQRVLEGRFRIPYFMSEDCEHLIRRMLVLDPSKRLSIAQIKEHKWMLIEVPVQRPILYPQEQENEPSIGEFNEQVLRLMHSLGIDQQKTVESLQNKSYNHFAAIYFLLVERLKSHRSSFPVEQRLDGRQRRPSTIAEQTVAKAQTVGLPVTLHPPNVRLMRSTLLPQASNVEAFSFPTSSCQAEAAFMEEECVDTPKVNGCLLDPVPPVLVRKGCQSLPSSMMETSIDEGLETEGEAEEDPSQAFEAFQATRSGQRRHTLSEVTNQLVVMPGAGKMFSMSDNPSLESVDSEYDMGSAQRDLNFLEDSPSLKDIMLANQPSPRMTSPFISLRPANPAMQALSSQKREAHNRSPVSFREGRRASDTSLTQGIVAFRQHLQNLARTKGILELNKVQLLYEQMGSNADPTLTSTAPQLQDLSSSCPQEEISQQQESVSSLSASMHPQLSPQQSLETQYLQHRLQKPNLLPKAQSPCPVYCKEPPRSLEQQLQEHRLQQKRLFLQKQSQLQAYFNQMQIAESSYPGPSQQLALPHQETPLTSQQPPSFSLTQALSPVLEPSSEQMQFSSFLSQYPEMQLQPLPSTPGPRAPPPLPSQLQQHQQPPPPPPPPPPQQPGAAPTSLQFSYQTCELPSTTSSVPNYPASCHYPVDGAQQSNLTGADCPRSSGLQDTASSYDPLALSELPGLFDCEMVEAVDPQHNGVVSCLARET
What is the function of this protein?
Serine/threonine-protein kinase that plays a role in many biological processes such as fatty acid oxidation, autophagy, immune response or glucose metabolism (PubMed:12624099, PubMed:16817901, PubMed:29211348).  Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction (PubMed:12624099).  Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators (PubMed:16817901).  Phosphorylates EP300 and thus inhibits its histone acetyltransferase activity.  In turn, regulates the DNA-binding ability of several transcription factors such as PPARA or MLXIPL (By similarity).  Also plays a role in thymic T-cell development (PubMed:34732767).
What are the official names of this protein?
Serine/threonine-protein kinase SIK2, Salt-inducible kinase 2, SIK-2, Serine/threonine-protein kinase SNF1-like kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: NOSL_BOMMO
Sequence: MAIPGRGDVPRDPEEVLNDAKDFLGQYFASIRRANTPAHEARWKIVQEEVATTGTYQLTTTELVFGAKLAWRNASRCIGRIQWSKLQVFDCRQVTTTSGMFEALCNHIKYSTNKGNIRSAITLFPQRTDGKHDYRIWNSQLISYAGYRQPDGTVLGDPMHCEFTDLCLKLGWKPPRTAWDILPLVLSANGKDPDYFEIPRELVMEIHMTHPTFEWFKELELRWYALPAVSSMRFDCGGIEFTANAFNGWYMSTEIGCRNFCDTNRLNVLEKIAQNMGLDTRTPVNLWKDKALVEVNVAVLHSFQQHNATIVDHHTASESFIKHLDNENRLRSGCPADWIWIVPPMSSSITPVFHQEMALYYLKPSYEYQEPAWKTHQWQKSKPITGKRPINRKFHFKQIARAVKFTSKLFGRALSKRIKATVLYATETGKSEQYAKELGVIFGHAFNAQVHCMADYDITSIEHEALLLVVTSTFGNGDPPENGVAFGEHLCEILYADQVGEDSTGNQMLTPKSFIKANSDIQRYTAGNPKKLNRLESLKGSTTDATSIDSFGPLSNVRFAVFALGSSAYPNFCNFGKYVDKLLVDLGGERIHDLATGDEMCGQDQAFRKWASSVFNVACETFCLDDDETLQEAKRALGTVALSEETVQFARAGCRPATLHAALQKSLNKQFVSCTVKANKDLGDASAERSTIFIDLEPKEEIKYNPGDHVGIIACNRKELVESLLSRIKDVDDYDEPLQLQLLKETHTSSGLVKSWEPHEKLPIMSVRELFTRFLDITTPPTTILLQYLATTCEDEEEKKQLNVLATDPGAYEDWRHFHFPTLPEVLDQFPSARPNASLLAALLSPLQPRFYSISSSPLAHAKRLHLTVAVVTYRTQDGEGPVHYGVCSNYLMERKPGDEVYLFIRSAPNFHLPQDLSVPLILIGPGTGIAPFRGFWHHRRALQNSCSRTTTGPVWLFFGCRTKTMDLYREEKEQALKEGVLSKVFLALSREKEVPKTYVQEVAENVGAEIHDLLINKGAHFYVCGDCKMAEDVHQKLKGIVKKHGNMTDEQVQNFMFMLKEENRYHEDIFGITLRTAEVHSASRESARRNRVASQP
What is the function of this protein?
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
What are the official names of this protein?
Nitric oxide synthase-like protein.
What is the protein family that this protein belongs to?
Belongs to the NOS family.
Protein: YL122_YEAST
Sequence: MNRLYQNCMFLYVYTDVCVRLCASIFYIMLEAKFALRIPALRPSYTWGQWRSFIQSSFYGRTFVAFSGPSMKNYITICFLLKSIEVSVDRTALHGTSAEASASNFQRIQTKNLSKYNCNIPACCV
What are the official names of this protein?
Uncharacterized protein YLR122C.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: Y1239_METJA
Sequence: MIGIAIKPSKINEDIVDFGHFIGRYFDYYIIDAENEVIKDEEILERLEKISKVVMTVQAKRVDAFELLELYASYGFDLCVVLGNKQYLTEKERKFKNYRILDVIKEAMRCSRDIWVGIEGVESLVKDIVEEHNLIAYYLYGQECSINSKRAIYVPYATKINENALESMKGYLNRRKNYRGNWRDFILSLNDEESIERIKNNDIVVGYPIIPNKEEILNFVRCFSV
What are the official names of this protein?
Uncharacterized protein MJ1239.
Protein: RFCL_META3
Sequence: MNWVEKYRPKTMSEIVGNNKIKEELKNWIEEILHNEIPKPVLLVGPPGCGKTTLTNALANDYGFELIELNASDKRNKDIIRQIVGGASSSKSITGKRVLIVLDEVDGLSGNSDRGGVSEIIKIIKNAKNPIILTANDIYKPSLMSLRTVCNIVKIGSVHTNSIVPVLRRISLKEGFEVDDKILKIIAKHAGGDVRSAINDLESLAMGNTFDEDNVRELPDRDTDKSIFDAIRIIFKTTHYDISLEATRDLKEDIGTVQEWIAENVPREYKKGKEICLAYDNLSKADIFLGRVYKRQYYGLWRYASALMSAGVSLAKDEKYRGFFSYMRPTIFTKMSRSKGKRGAVNKVLEKISLKSHVSKRRAREDILYLEYILKNDAEMGAKLCEFYEFTKEDIEYLTNKTIAKKIIKLMKGDDKKTNNKKGKENKTKNTTKKIKEIKETPKKEEVKEPKKQIEKQKSEKKEPKKQMTLESFF
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.