PharMolix/UniProtQA huggingface dataset:
Protein: AROC_XANOP
Sequence: MSANAFGKLFTVTTFGESHGPAIGCVVDGCPPGLEIAPEEFSHDLQRRASGKSRHTSARREADEIEILSGVYEGRTTGTPIGLLIRNTDQRSKDYSNIAQQFRPGHADYTYWQKYGIRDPRGGGRSSARETTMRVAAGVIAKKWLKQRYGVLVRGFLSQLGEIRPAGFDWDAVEDNPFFWPHAAQVPELETYMDALRKSGDSVGARVDVLAGGVPAGWGEPIYGKLDAELAAALMSINAVKGVEIGDGFASAAQKGTEHRDLITPEGFRSNHAGGILGGISTGQAVTASMVLKPTSSLRLPGATVDADGSVVDVITTGRHDPCVGIRATPIAEAMMALVLMDQALRHRAQCGDVGEISPRIPGQVDV
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ATPG_RHIWR
Sequence: MASLKALKVRITSVKSTQKITKAMKMVAAAKLRRAQMAAEAGRPYAERLDAVMSSLASKVTVGPQSPKLLAGTGNDQVHLLVVATSERGLAGAFNTNIVRAARKTADSLIAQGKTVKFYLIGKKGRAVLQRLFPGKIVHQVDQSHIKNVAFSDAHMVAEDLIGRYSAGEFDVAHLFFAKFQSALVQEPTELQIIPVPLTADTGAAATGASAAVEYEPDEEAILTELLPRNVAVQLFRAMLENAASEQGSRMTAMDNATRNAGEMINKLTIQYNRTRQAAITTELIEIIAGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SPED_ECODH
Sequence: MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
Protein: CALD1_BOVIN
Sequence: QTSEKEGRSESRQERQELEETEIVTKSHQKNDWMEAEEKKKEEKEKEEEEEEKPKPGSIEENQLKDEKTKKDKESKNILSLCL
What is the function of this protein?
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments).  Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure.  In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin.  This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin.  Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin.  Also plays an essential role during cellular mitosis and receptor capping.
What are the official names of this protein?
Non-muscle caldesmon, CDM, L-caldesmon.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, myofibril. Cytoplasm, cytoskeleton, stress fiber. Note=On thin filaments in smooth muscle and on stress fibers in fibroblasts (nonmuscle).
Protein: LPXC_LEPIC
Sequence: MKEILYRRSIQDTVRIKGIGLHSGKEVNLTAHPAPSGTGIVFEYRKGLEKASISAELSNVVDTSNATTLGDGIHKIQTVEHLLAAVYALGLTDLILEIDAVEVPIMDGSSLPFLQALESAGIIEYPEIVEPIYIQSPLWVVDGDKYLVLLPSDELKVTYTIDFNHPLLKGQSITVSLDREKIKQEILPARTFGFLKDVEALQARGLAMGGSLDNAIVLTQDGYLNQQLRFENECVRHKILDLFGDISIAGRPIIGHYLASKAGHALDISMAKLVMSNVTGDEISKYKSRRIPLFKRKAVVV
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: DNBI_MUHVS
Sequence: MADDDLSSLAPVAPAVWMFFLKKTRELADIVAAMSLCDKATPVVIAPLLIDLTVDRDFCGAVRTPMSTYEGGVLTKVTSFCPFAFFFHNTDEILDVVEDHGDVVHLCDDARRRFGVQAFSPLANRDRTDVDVLCDELGIAPAEYTGHVVCGNGLKELLYAGQLIPCPEEAVKVQVGAVDGVKVPLYPYTLFSGGADAAHADGPSAAVACDDPWVLEHGFYDPALSEALFYFMFTSWGQSLRVCETSRLIEAGLQQFVEDTQQTVKLTPFKKYHGYTSQKLTAVERDQLMTVDAVCSELAFSYASIYLDSVYEFSTASNFLEWPLVKNAKTHADLLDNLRDFQLHLAKHIAALIFSSNSILYQTRIVFVPSAGKGANSNPSAQDSLLKSIRFFNGLTGMYDDILNDAKKTIRFEGAVGRDEKYSPHHLAYFCGTSPQLFSTLMWFFNRMSIYSTGVTSGDTVFSHIVNAGSKLCGACGGRCCHTCYATSFIRVNTRLPGIPKQIKKEPVVVTLLSRAFADADLLGNYGKRYGLESREAGDGGGGGAGGRTDEVAAGPPAGGASGLNFVSVDRMKYLGQVLDYCKKNSLIDAITGEDIINVRTKRDFVATVTALNQTIDDAVCRFAMDVRRSGHGRDEISGSTQSFNLDLSPYATAFSPVLSFQYYRTMFSIIQNLALINAASYVVDNPLTTAQISKWVTLHFQSICGAFGTTPLKKGFLNVKDTKNLKSVEFERIMDFRSFQETGRYRKISTEIKSCKMSVQSLKSCRIKNRPISKTPQSSVFFKKGALQRKNPIKGCLSFLLFRCHEKLFPRCGLSCLEFWQRVLQNSLPRSVNVGKVEDFDNLVRFLLTVTDDYDESDVVDIQPDCLLSYVENRFHNKFLYMFGFRDYMSTIQGMSTRLTPQNHSQFPCLLKDAPKFASIAEYVLHFKKMKLDGVKAPQVATITREPVLKKLFDGRSLVSVSFAVEKYSSSMGTRDVFQFGQIGYYVGSGVDRSLNTGSMGTQDYRFMRYRYIIATKLVDVLIRRSRRENVMYDRDVVRSRVLAALDSTGLDVDPELAAIAELMEGRDEGDIPEIDDILFYVDQQEYIARSMYRKMRSLAERGVTDFSLASLREATATNATAAGSAAGGGGSATEGGGGGAAADESGPMYDFSALFSRRDEAEDVNAGLINGDDVRGDDEFELPSKRSRL
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: Y1891_SULIK
Sequence: MPISGVDDGYFPLSYKGGKGKTALVVVTFYDYEMIDLDWGLITVDGNDATDVLKQLRKGDIVILDGVIFAGFNYIVPYSDNMIFFYSKMPKVDLIKNALMKHFQADTERVREILYVLNNLKQIPTKRGNVFLYSTVELSLAKSIIEKYQIYSKIPEVLKSAHVIASSLGRFLARYKKTI
What are the official names of this protein?
UPF0215 protein M164_1891.
What is the protein family that this protein belongs to?
Belongs to the UPF0215 family.
Protein: Y1190_SHESM
Sequence: MSAVIMQQGDLLLNLYIQPKASRDQIVGLHGDELKVAITAPPIDGKANAHLSKYLAKAFKVPKSDVHILKGELGRHKQVRISAPKNVPAEIATLLE
What are the official names of this protein?
UPF0235 protein Shewmr4_1190.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: ISPT_STRMU
Sequence: MFTLRRKKQDIKLSKIPAHIGIIMDGNGRWAKKRMKPRVFGHKAGMDALQDVTIAASELGVKILTVYAFSTENWARPQEEVKFIMNLPVEFFDKYVPKLHKNNVRILVIGDKEELPAATLDALERARELTKHNSGLILNFALNYGGRAEIVDAVKLIAQDVLDARFNPGDITEGLIADYLMTSNLPYLYRDPDLIIRTSGELRLSNFLPWQAAYSELYFTDTLWPDFDKKALYLAIEEFNHRHRRFGGV
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: DXS_NITHX
Sequence: MGVCCATAPASDRRSRHPDMQNWNVAVTDFSKTPLLDTIRTPADLRKLRVEQLRQVADELRKETIDAVSVTGGHFGAGLGVVELTTAIHYIFDTPRDRLIWDVGHQAYPHKILTGRRDRIRTLRTGGGLSGFTKRTESDYDPFGAAHSSTSISASLGMAVARDLSGGKNNVIAVIGDGAMSAGMAYEAMNNAGAMNSRLIVILNDNDMSIAPPVGAMSAYLSRLYSGKTYRSLREAAKQLGKHLPKMIADRAERVEEYSRGFMVNSGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDMENGPILLHVVTQKGKGYGPAEAAADKYHAVVKFDVSTGAQSKSKPNAPAYQNVFGQSLVKEAEKDDKIIAITAAMPSGTGVDIFNKAFPKRTFDVGIAEQHAVTFAAGLATEGFKPFCAIYSTFLQRGYDQIVHDVAIQSLPVRFAIDRAGLVGADGATHAGSFDNAYLGCLPNFVIMAASDEAELVHMVATQVAINDRPSAVRYPRGEGRGVEMPEVGVPLPIGKGRIVRQGSKVALLSLGTRLAECEKAADELAAHGLSTTIADARFMKPLDVDLVLKLARDHDVLITIEEGSIGGFGSHVMQTLAEHGALDSGQVRVRAMVLPDEFLDHDTPNAMYASVGLDDRGIVAKVFEALGKDVTTETVKLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: IBPB_ECO55
Sequence: MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_BRUA2
Sequence: MSVTLALPSKGRLKEKTLAVLEKAGYKVVLPDDDRNYRARVEGEDDLDILFLSASEIARELGYGSVDLGVTGEDLVRETLAHADERVAIEAQLGFGHADVVVAVPEVWRDVTTMADLDDVAADFRQRHGRRLRIATKYWRLTQQFFSQKHGIQVYRIVESLGATEGAPAAGSADMIVDITSTGSTLRANRLKVLEDGIILRSQACLVSARRSHTSRRVEEIAARIRAGLEI
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AIM9_YARLI
Sequence: MQSWNSQSFLSSHFTMLRYACKRAVPRLNAASGLRFQSSKPADGPETVFTSLNEENDPNRDAFFKYTWGTWLKNNEAERAKRETRFSIEGLAEVIKSLPQSGKAPIEAETEIKVTQLASLHEGKHHRVYRVDVDDGKQYVLRIPYGLGSELFRKKRIQSEVATMDFVREKVANNKFIVPEVYSWNATVDNPLDTQYTLMDYFAGRDTLMKHWNPVAQEMTERAAKIKPVVDIYSALLQPEFTRYGSLYFTEDVSSKDASVLAYKGAENDKKELADRWRIGPTTESRFWKNSLPEDSPLRGPWETAEEYIEATAAINLHNLAELAKNGDRNPAVVAAATATYEKYQQLASQLLLRPEVENDNLFSARMGFGDLHPINVLVEGQKDIAESSLALVDFENTSIKPALLIGTPDYVRYGGLKLFKTEDIPNYDQLSDQEKAQVNYMIAQTQNAFTFEFLLNNEAPEFINSFSPRVKRLSEPVRLALNPLYLEDHLDLSEEMIKLQQDWTPIMGMEREFPVHWTNEEYEKQAKDFAEWNQKAMSTPFFQTKGWVPQDMFEQLFGNGLLDKTESGDYVYVPPKKE
What are the official names of this protein?
Altered inheritance of mitochondria protein 9, mitochondrial, Found in mitochondrial proteome protein 29.
What is the protein family that this protein belongs to?
Belongs to the AIM9 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PROA_PELPB
Sequence: MKETITKQLIAVQQASREIITLTDETINSLLCALADSIPSHQEAILQANQKDIERMDPADPMVDRLLLNASRLDAIAADIRNVASLPSPLDALLEERVLPNGLNLKKVTVPIGVIGIIYEARPNVTFDVFALCLKSGNATVLKGGSDAMYSNIAIVELIHSVLKQHGINPDTLYLLPAEREAAAVMLNAVGYIDMIIPRGSQKLIDFVRNNAKVPVIETGAGIVHTYFDKSGDLDLGKHIIFNAKTRRPSVCNALDTLVIHQERLADLPALVEPLQEKQVMLFADEAAFQALQGSYPDDLLHQAEPEHFGTEFLSLKMSVKTVSSLEEALEHITRYSSRHSEAIIATDPETTATFLKRVDAAVVYANTSTAFTDGAQFGLGAEIGISTQKLHARGPMALKELTTYKWIIEGNGQTRPA
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAHH_MARMM
Sequence: MTQFAADKPYIVKDMSLAKWGRIEFDMAEIEMPGLMALREEYKDSQPLKGARIAGSLHMTVQTAILIETLTALGAEVRWASCNIFSTQDHAAAAIAETGVPVFATKGETLEEYWDYADAIFHWPDGETANMILDDGGDATMYLILGEKAENDPSVLNHPKSEEETFLFAQIKKRIAATPGWFAKAKAAIQGVSEETTTGVMRLYQMQKRGELPFPAINVNDSVTKSKFDNRYGCRESLVDAIRRGTDVMMAGKKALVFGYGDVGKGSAESLAGAGARVYVTEIDPICALQACMDGFEVVRAEDVIGEMDIFVTATGNKDILTVDHMRAMKDMAIVCNIGHFDNEIQVESLKNYQWTNVKPQVDLVNFPEGHRIILLSEGRLVNLGNATGHPSFVMSASFTNQTLAQIELWTKGENYTNEVYILPKHLDEKVAALHLDKLGAKLTVLSDEQADYIGVPQHGPFKAEHYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIP3_ARATH
Sequence: MKLAGLKSIENAHEDSVWAATWVPATEDRPALLLTGSLDETVKLWRPDELDLVRTNTGHSLGVAALAAHPSGIIAASSSIDSFVRVFDVDTNATIAVLEAPPSEVWGMQFEPKGTILAVAGGSSASVKLWDTASWRLISTLSIPRPDAPKPSDKTSSKKFVLSVAWSPNGKRLACGSMDGTICVFDVDRSKLLHQLEGHNMPVRSLVFSPVDPRVLFSGSDDGHVNMHDAEGKTLLGSMSGHTSWVLSVDASPDGGAIATGSSDRTVRLWDLKMRAAIQTMSNHNDQVWSVAFRPPGGTGVRAGRLASVSDDKSVSLYDYS
What is the function of this protein?
Component of the PAF1 complex (PAF1C) which is involved in histone modifications such as methylation on histone H3 'Lys-4' (H3K4me3) (PubMed:20363855).  Involved in regulation of flowering time.  Required for the expression of the flowering repressor and MADS box gene FLC (PubMed:12750345, PubMed:18725930).  Required for histone H3 trimethylation on 'Lys-4' (H3K4me3) and histone dimethylation on 'Lys-36' (H3K36me2) at the FLC locus.  Prevents trimethylation on 'Lys-27' (H3K27me3) at the same locus (PubMed:18725930).  Not required for meiotic recombination or progression (PubMed:16716192).  Component of the SKI complex which is thought to be involved in exosome-mediated RNA decay and associates with transcriptionally active genes in a manner dependent on PAF1 complex (PAF1C) (PubMed:22511887).  Required for proper progression of cell differentiation process (PubMed:23134555).
What are the official names of this protein?
WD repeat-containing protein VIP3, Protein BOUQUET-1, boq-1, Protein SKI8 homolog, Protein VERNALIZATION INDEPENDENCE 3, Protein ZWERGERL, zwg.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LIPL_CAVPO
Sequence: MNIDRKILNKALAKEKVANCQKDYTDIESKFARRTPENTVEDTCHLIPGVTESVANCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKREPDSNVIVVDWLRRAQHHYPESADYTKLVGEDVARFINWMEDEFKYSVDNVHLLGYSLGAHAAGVAGSRTNTKVSRITGLDPAGPNFEYAEATSRLSPDDAQFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGSFQPGCNIQDALRVISQKGFGDMDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNVGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIYFSGTETTTYTNQAFEISLYGTVAESENIPFTLPEVSANNTYSFLIYTEVDIGELLMLKLKWITESYFSWSSWWGRPTFTIEKIRVKAGETQKKIVFCSREKVSKLQKGKEAPVFVKCHDKSLNKKSG
What is the function of this protein?
Key enzyme in triglyceride metabolism (By similarity).  Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (By similarity).  Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (By similarity).  Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity).  Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity).
What are the official names of this protein?
Lipoprotein lipase, LPL, Phospholipase A1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Secreted, extracellular space, extracellular matrix. Note=Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells. Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non- coated endocytic vesicles.
Protein: LEU3_LISIN
Sequence: MAYKITSLAGDGIGPEIMASGIKILEAIAAKYNHTFEIESHPFGGAGIDAAGDPIPPETLKACQNADAILLGAIGGPKWDNAPKRPEDGLLALRKALGLFANIRPIQVPSSITHLSPLKKEIVENTDFVVVRELTGGLYFGEPKHWDDVAAVDSLTYTRVEIERIIEKAFEIASTRNKKVTSVDKANVLASSKLWRKIAEEVASRHPDITLEHLYVDAAAMLMIQRPTTFDVIVTENLFGDILSDEASVITGSLGMLPSASHAENGPSLYEPIHGSAPDIANQNIANPMSMISSVSMMLRQSFSLFKEADAIDAATARTMQAGFLTADLGGNTSTTDFTNEVLKQIEGGE
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF5A_THEAC
Sequence: MSWQEAEVRELKVGRYILIDDAPCKIVEITMSKPGKHGEAKGRIVAIGVFDNQKRSVVYPVKHKVKIPIIEKKNAQVLSVQNNEVQLMDSETFETFVLPLDPEIADKIKPGMEVPYWETMGMRKIMLQN
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPCKG_HALLT
Sequence: MLTLPESLRDAFKEPLGPVTIDADELLAAAAETRGERAAPDAPIIAVGDVVTYHLREAGRVPDVALIDGKTERETVDAEIGSALAAADDRRLSVENPAASLSAELLEALSEALSDADPVIIEVTGEEDLAALPAILAAPDGASVVYGQPGEGMVRVAVTPESRTEARELFEALDGDVEAAYKALGRVPDGDR
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: RS14_POLSJ
Sequence: MAKQALLQRELKREKLAAKFAKKYAELKATSNDAKRSDEERALARLELQKLPRNANPTRQRNRCAITGRPRGTFRQFGLARAKIRELAFAGDIPGITKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PAND_PECCP
Sequence: MIRTMLQGKLHRVKVTQADLHYEGSCAIDQDFMDAAGILEYEAIDIYNVDNGQRFSTYAIAGERGSRIISVNGAAARLACVGDKLIICSYVQMSDEQARSHNPKVAYFSGDNELQRQAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIE_BACTN
Sequence: MVSLQFITHQTDRYTYFESALMALEGGCKWIQLRMKEAPCEEVEAVALQLKPLCKEKEAILLLDDHVELAKKLEVDGVHLGKKDMPIDQARQLLGEAFIIGGTANTFEDVVQHYRAGADYLGIGPFRFTTTKKNLSPVLGLEGYTAILSQMKEANIELPVVAIGGITREDIPAILETGVNGIALSGTILRAEDPAAETRKILNMKRIIK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: CHSB_PEA
Sequence: MVTVDEIRQAQKAEGPATVLAIGTATPPNCVDQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMHLTEEILKENPSVCEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPHVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPLPQVEKPLFELVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSLFWIAHPGGPAILDQVEAKLSLKQRKMQATRHVLSEYGNMSSACVLFILDEMRRKSKEEQLGTTGEGLEWGVLFGFGPGLTVETVVLHSVAT
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 1B, Naringenin-chalcone synthase 1B.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RUTC_CAUVC
Sequence: MPKTVITPPGTQTPIAPFSPGTLADGIVYVSGTLAFDKDNNVAFPGDAEAQTRQVLETIKSVIETAGGTMEDVTMNHIFLTDWVHYAPMNKVYAEYFPGDKPARYCIQCGLVKPGFVVEIASVAHIGKT
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: MCFD2_PONAB
Sequence: MTMRSLLRTPFLCGLLWAFCAPGARAEEPAASFSQPGSMGLDKNTVHDQEHIMEHLEGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYIDYAEFAKSLQ
What is the function of this protein?
The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
What are the official names of this protein?
Multiple coagulation factor deficiency protein 2 homolog.
What are the subcellular locations of this protein?
Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.