PharMolix/UniProtQA huggingface dataset:
Protein: SYFB_STRA1
Sequence: MLVSYKWLKELVDVDVTTAELAEKMSTTGIEVEGVETPAEGLSKLVVGHIVSCEDVPDTYLHLCQVDTGDDELRQVVCGAPNVKTGINVIVAVPGARIADNYKIKKGKIRGMESLGMICSLQELGLSESIIPKEFSDGIQILPEGAIPGDSIFSYLDLDDEIIELSITPNRADALSMRGVAHEVAAIYGKKVHFEEKNLIEEAERAADKISVVIESDKVLSYSARIVKNVTVAPSPQWLQNKLMNAGIRPINNVVDVTNYVLLTYGQPMHAFDFDKFDGTTIVARNAENGEKLITLDGEERDLIADDLVIAVNDQPVALAGVMGGQSTEIGSSSKTVVLEAAVFNGTSIRKTSGRLNLRSESSSRFEKGINYDTVSEAMDFAAAMLQELAGGQVLSGQVTEGVLPTEPVEVSTTLGYVNTRLGTELTYTDIEEVFEKLGFAISGSEVKFTVLVPRRRWDIAIQADLVEEIARIYGYEKLPTTLPEAGATAGELTSMQRLRRRVRTVAEGAGLSEIITYALTTPEKAVQFSTQATNITELMWPMTVDRSALRQNVVSGMLDTIAYNVARKNSNLAVYEIGKVFEQTGNPKEDLPTEVETFTFALTGLVEEKDFQTKAKPVDFFYAKGIVEALFIKLKLDVTFVAQKGLASMHPGRTATILLDGKEIGFVGQVHPQTAKQYDIPETYVAEINLSTIESQMNQALIFEDITKYPSVSRDIALLLAESVSHHDIVSAIETSGVKRLTAIKLFDVYAGNNIAEGYKSMAYSLTFQNPNDNLTDEEVAKYMEKITKSLVEKVNAEIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_XANOM
Sequence: MTEVEARIQLEPSWKAKVGDWLLCSQMQELSAFLRQRKAVGARVFPPGPQIFAAFDATPFDQVKVVILGQDPYHGEGQAHGLCFSVLPGVPVPPSLLNIYKEIQDDLGIARPDHGYLMPWARQGVLLLNAVLTVEQGRAGAHQNKGWEGFTDHVVETLNREREGLVFLLWGSYAQSKGRVIDQARHRVFKAPHPSPLSAHRGFLGCQHFSKTNAHLQRRGISPIDWSLPPRNELDTTSAGA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_HPBDW
Sequence: MDINASRALANVYDLPDDFFPKIDDLVRDAKDALEPYWKSDSIKKHVLIATHFVDLIEDFWQTTQGMHEIAESLRAVIPPTTAPVPTGYLIQHEEAEEIPLGDLFKHQEERIVSFQPDYPITARIHAHLKAYAKINEESLDRARRLLWWHYNCLLWGEANVTNYISRLRTWLSTPEKYRGRDAPTIEAITRPIQVAQGGRKTSSGTRKPRGLEPRRRKVKTTFVYGRRRSKSRERRAPSPQRAGSPLPRSSSSHHRSPSPRK
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsid appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsid are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stucked in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genome for transcription, or bud through the endoplasmic reticulum to provide new virions (By similarity).
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg.
What is the protein family that this protein belongs to?
Belongs to the avihepadnavirus core antigen family.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm.
Protein: METAA_BIFAA
Sequence: MPIKIPSGLPARDILDSERIFALEKPEAERQRVRPLKLVILNLMPKKIETETQLLRLISKSPLQVEVDFMKTSTHEATHVSADHLVKFYETLDAFKDNYYDGLVVTGAPVEHLDFEQVDYWDEFKQILDWASTHVFSTMYLCWGAMGALNYRYGVRKELLPEKLFGVFPQYLQDEYCFLTNGFDEICLQPHSRLAGVNEGDIAHNPELQVLTWGPKSGPGLIATRDFSEVFALGHWEYGKYTLAEEYERDMKKGMTNVPFPENYFPHDDPKLEPLFAWRAHANLLWRNWLNWVYQTTPYDLSEVPQLREEKRLGTDRSIRHEPGSPRVDAFTPFSHDGYGVIRG
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the MetA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1590_METJA
Sequence: MRISPLIAGLIGGFTAAILQALFKVFPPPAYGICIACHTRDLVNWIINHLFGTTLGMALVSKAFPVLTVVGIFIGALITTFIYKETELKQTHSPVYWFHIRNFSY
What are the official names of this protein?
Uncharacterized protein MJ1590.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SECY_RICCN
Sequence: MGQNFSKKSGNDLVSRIVFTILILIVCRFGSFIPIPGIDSIALSSVAAQNQSGILGMFNMLSGGSLGRMSIFALAIMPYITASIIIQLMSVAYKPLENLKKEGEVGKRKVNQLSRYLTVLLASFQAYGVAISLESIVTNTGPVVILAGFFFRITTVITLVVGTMLLMWLGEQITQRGIGNGTSLIIFIGIISGVPSAIISMFELSRKGALSPLIAIAVCIGVVVLIAIIIFFERAQRKLLVQYPKRQVGNKIYGGEATHMPLKLNTSGVIPPIFASSILLFPATLANFSNSNSETMGMLTYYLGHGKPVYILLYVALIMFFSFFYTAIVFNSEETANNLRKYGAYIPGKRPGKNTSDYFDYILTRLTVIGGIYLSVICVIPELLMNKYVISLSLGGTSFLIVVNVVLDTMTQIQTYLFSSKYEGLMKKVKLKN
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TM39B_MOUSE
Sequence: MGGRRGPNRTSYYRNPLCEPGSSGASGGGHSSSASVSSVRSRSRTTSGTGLSSPPLAAQTVVPLQHCKIPELPVQASILFELQLFFCQLIALFVHYINIYKTVWWYPPSHPPSHTSLNFHLIDFNLLMVTAIVLGRRFIGSIVKEASQRGKVSLFRSILLFLTRFTVLTATGWSLCRSLIHLFRTYSFLNLLFLCYPFGMYIPFLQLNYDLRKTNLFTHMASMGPREAVSGLARSRDYFLTLRETWKQHTRQLYGPEAMPTHACCLSPSLIRNEVEFLKMDFNWRMKEVLVSSMLSAYYVAFVPVWFVKNTHYYDKRWSCELFLLVSISTSVILMQHLLPASYCDLLHKAAAHLGCWQKVDPALCSNVLQHPWTEECMWPQGVLVKHSKNVYKAVGHYNVAIPSDVSHFRFHFFFSNPLRILNILLLLEGAVIVYQLYSLMSSEKWHQTISLALILFSNYYAFFKLLRDRLVLGKAYSYSASPQRDLDHRFS
What is the function of this protein?
May protect the cells against DNA damage caused by exposure to the cold-warming stress and facilitates tissue damage repair during the recovery phase.
What are the official names of this protein?
Transmembrane protein 39B.
What is the protein family that this protein belongs to?
Belongs to the TMEM39 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BETB_ACIBS
Sequence: MSDVQVHQLYIHGRYVEATSGKTFNSINPANGEIIATLQQASEQDIEAAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELARLETLDTGKAYSETSTVDIVTGADVLEYYAGLATAIQGEQVPLRESSFFYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSETTPLTALKLAEIYTEAGLPDGVFNVVQGAGREIGQWLTEHPVIEKISFTGGVETGKKVMASAAGSTLKEVTMELGGKSPLIICEDADLNRAADIAVMANFFSSGQVCTNGTRVFVPKSRLADFEKAVVERVKRILIGDPMAEDTNFGPLTSFPHMEKVLSFIESGKQQGAKVLIGGGRATEGELAKGAYVLPTVFSDCTDQMAIVQEEIFGPVMSILGYETEEEVIQRANDTTFGLAAGVVTQDISRAHRIIHQIEAGICWINTWGESPAEMPVGGYKQSGVGRENGLTTLGHYTRIKSIQVELGDYQGIF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: ATPB_RUEST
Sequence: MANAKGKVTQIIGAVVDVQFDGELPAILNALTTDNNGKKLVLEVAQHLGENSVRTIAMDATEGLVRGQEVTDTGAPISIPVGNATLGRILNVVGEPVDEGEPIVAKETRAIHQPAPEFNDQSTESEVLVTGIKVIDLLAPYAKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESNVIKPDNLEESQVALVYGQMNEPPGARARVALTGLTLAEQFRDQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGAMQERITSTKNGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLNRAISELGIYPAVDPLDSSSRLMDPQIVGEEHYKVASDVQQILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVFTGSDGVQVSLEDTIASFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAEKMAADAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ERAL1_HUMAN
Sequence: MAAPSWRGARLVQSVLRVWQVGPHVARERVIPFSSLLGFQRRCVSCVAGSAFSGPRLASASRSNGQGSALDHFLGFSQPDSSVTPCVPAVSMNRDEQDVLLVHHPDMPENSRVLRVVLLGAPNAGKSTLSNQLLGRKVFPVSRKVHTTRCQALGVITEKETQVILLDTPGIISPGKQKRHHLELSLLEDPWKSMESADLVVVLVDVSDKWTRNQLSPQLLRCLTKYSQIPSVLVMNKVDCLKQKSVLLELTAALTEGVVNGKKLKMRQAFHSHPGTHCPSPAVKDPNTQSVGNPQRIGWPHFKEIFMLSALSQEDVKTLKQYLLTQAQPGPWEYHSAVLTSQTPEEICANIIREKLLEHLPQEVPYNVQQKTAVWEEGPGGELVIQQKLLVPKESYVKLLIGPKGHVISQIAQEAGHDLMDIFLCDVDIRLSVKLLK
What is the function of this protein?
Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly.  Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region.  May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.
What are the official names of this protein?
GTPase Era, mitochondrial, H-ERA, hERA, Conserved ERA-like GTPase, CEGA, ERA-W, ERA-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes on the matrix side on the mitochondrial inner membrane.
Protein: STX12_PONAB
Sequence: MSYGPLDMYRNPGPSGPQLRDFSSIIQTCSGNIQRISQATAQIKNSMSQLGTKQDSSKLQENLQQLQHSTNQLAKETNELLKELGSLPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIARARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQDDEVAITEQDLELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMCILVLVLSVIIVILGLIIWLVYKTK
What is the function of this protein?
SNARE promoting fusion of transport vesicles with target membranes.  Together with SNARE STX6, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway.  Through complex formation with GRIP1, GRIA2 and NSG1 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting.
What are the official names of this protein?
Syntaxin-12.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Endosome membrane; Single-pass type IV membrane protein. Golgi apparatus membrane; Single-pass type IV membrane protein. Endomembrane system; Single-pass type IV membrane protein; Cytoplasmic side. Early endosome membrane; Single-pass type IV membrane protein. Recycling endosome membrane; Single-pass type IV membrane protein.
Protein: Y1253_HAEIN
Sequence: MNFDRTFLTFLGVIMLVHLHIFFAFLSLALLVIRGAMQLNGKNWRSIKLLKILPHLSDTLLIVSGVVILYLFAFGIEWWLVAKFALLILYIVFAAKFFSKKVSQPKSIFFWLACVSFIGAMLIAYLK
What are the official names of this protein?
Protein HI_1253.
What is the protein family that this protein belongs to?
Belongs to the SirB2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSBE_PELHO
Sequence: MSGSTGERSFADIITSIRYWVIHSITIPSLFIAGWLFVSTGLAYDVFGSPRPNEYFTESRQGIPLITGRFDPLEQLDEFSRSF
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit alpha, PSII reaction center subunit V.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FB198_ARATH
Sequence: MTTISDLSDDLVGDILSRVPFTSLISVRSTCKKWNALSKNQIFGRKTAARNQFLEFMILDSRVCSLRLDLQGIRNEDKEDFVDPSMKLISIPSNDDQVEISQVYHCDGLLLCIAKENSNVFVWNPYLGQTKWIRPRNTFHRYDRFALGYDNNRNHKILRFLYDEESNESSRRTHIDVYDFSSDSWRVLDVNPDCDIPFYQTGVSLKGNTYFFGQEVTQATKVTEIETCLLCFDFTTERFGPCLPLLFYPPCPSFETVTLSWVRDEKLAVLYNHYVTAEIIEIRISTKIEPNAVSWSSFLTVDMSLVNGLPDHFSMYFEAKSFFIDEEKKVVVLFDSKEIKTCRYQMAYIVGDDGYFKSVNIGVSPNSQRKPGRLVCSSYVPSLVQLQD
What are the official names of this protein?
F-box protein At3g49510.
Protein: TRPB_PSESH
Sequence: MTQTNFRSGPDVNGLFGSFGGRYVAETLMPLVLDLNREYEAAKADPEFAKEMAYFQRDYVGRPNPLYFAERLTEFCDGAKIYFKREELNHTGAHKINNCIGQVLLAKRMGKKRLIAETGAGMHGVATATVAARFGLPCVIYMGATDIERQQANVFRMKLLGAEIVPVTSGTGTLKDAMNEALRDWVTNVDDTFYLIGTVAGPHPYPAMVRDFQAIIGKETKEQMQEKEGRLPDSLIACVGGGSNAMGLFHPFLDDASVEIIGVEAGGHGVDTDKHAASLNGGVPGVLHGNRTYLLQDGDGQITDPHSISAGLDYPGIGPEHAFLHEVKRVEYVSITDDEALDAFHQCCLLEGIIPALETAHALAEAMKRATNLRDDHLMVVCLSGRGDKDMQTVMNHMAAAEKTQEKLV
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: APBB2_MOUSE
Sequence: MSEVLPADSGVGTLAVFMASSGSTDIANRNSPATPPNTLNLRSSHNELLNAEIKHSDAKNSTPPKCRKKYALTNIQAAMGLSDPAVQPLLGNGSANIKLVKNGENQLRKAAEQGQQDPNKNLSPAAVINLTSEKLEVKDPHPQESSGCEILPSQPRRTKSFLNYYADLETSARELGQNLGPCQGVGEEKAQPGPGQAPVVIGNGDLLPQKPNKPQSSPEDGQVATVSSSPETKKDHPKTGAKTDCALHRIQNLAPSDEESSWTTLSQDSASPSSPDETDIWSDHSFQTDPDLPPGWKRVNDIAGTYYWHIPTGTTQWERPVSIPADLHGSRKGSLSSVTPSPTPENEKQPWSDFAVLNGGKINSDIWKDLHAATVNPDPSLKEFEGATLRYASLKLRNAPHGDDDDSCSINSDPEAKCFAVRSLGWVEMAEEDLAPGKSSVAVNNCIRQLSYCKNDIRDTVGIWGEGKDMYLSLENDMLSLVDPMDRSVLHSQPIVNIRVWGVGRDNGRERDFAYVARDKDTRILKCHVFRCDTPAKAIATSLHEICSKIMAERKNAKALACSSLQERTNMSLDVPLQVDFPTPKTELVQKFRVQYLGMLPVDRPVGMDTLNSAIENLMTSSSKEDWPSVNMNVADATVTVISEKNEEEVLVECRVRFLSFMGVGKDVHTFAFIMDTGNQRFECHVFWCEPNAANVSEAVQAACMLRYQKCLVARPPSQKVRPPPPPADSVTRRVTTNVKRGVLSLIDTLKQKRPVTETP
What is the function of this protein?
Plays a role in the maintenance of lens transparency, and may also play a role in muscle cell strength (PubMed:25757569, PubMed:27734846).  Involved in hippocampal neurite branching and neuromuscular junction formation, as a result plays a role in spatial memory functioning (PubMed:27734846).  Activates transcription of APP (By similarity).
What are the official names of this protein?
Amyloid beta precursor protein binding family B member 2, Amyloid-beta (A4) precursor protein-binding family B member 2, Protein Fe65-like 1.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Early endosome.
Protein: GRP1_PHAVU
Sequence: MATSKVLLSNVLFVFVCFGICSAARTLLTLEDRVNLHVGTVVGGYGGGGGSGGGGGGAAVELGGGGYGEGAGGGEGAGAGYGAAGGGHGGGGGNGGGGGGGADGGGYGGGAGKGGGEGYGGGGANGGGYGGGGGSGGGGGGGAGGAGSGYGGGEGSGAGGGYGGANGGGGGGNGGGGGGGSGGAHGGGAAGGGEGAGQGAGGGYGGGAAGGGGRGSGGGGGGGYGGGGARGSGYGGGGGSGEGGGHGGGYYP
What is the function of this protein?
Responsible for plasticity of the cell wall.
What are the official names of this protein?
Glycine-rich cell wall structural protein 1.0, GRP 1.0.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: SUFE_PHOLL
Sequence: MASLPDTNKLLRNFSRCRNWEERYLYMIELGAKLPPLTDEQRQPENLIAGCQSQVWILLRMNHQNKVEFIGDSDAAIVKGLVAIVFILFQGKTTQEILDLDVTEYFGKLSLEQHLTPSRTQGLHAMIHAIRNRTSKMV
What is the function of this protein?
Participates in cysteine desulfuration mediated by SufS.  Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process.
What are the official names of this protein?
Cysteine desulfuration protein SufE.
What is the protein family that this protein belongs to?
Belongs to the SufE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_PELUB
Sequence: MTKRISAKHKIDRRLKINLWGRPKSPFNKRDYGPGQHGQGRKGKPSDYGIQLQAKQKLKGYYGNINERQFRNIYKKATMLKGDTGENLIGLLERRLDSVVYRARFSTTVFSARQLINHGHVRVNGKKVNIGSYVVKEEDIIEIRDKSKQLAIIDIALASKERETPEYINLDEKNKKVTFVRTPKFDEVPYPVIMEPNLVIEYYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: IOLG_BURO1
Sequence: MTLQIGVIGCGAIGQDHIRRLTRTLSGARVVAVNDIDPQQARDAVTKYGLDAEIYGDGHEVVAAADVQAVLVTSWGPTHEAFVLDAIAHGKPVFCEKPLAVTAEGCMRIVEAEVAHGKRLVQVGFMRPYDEGYRALKRVIDSGQIGAPLMLHCAHRNQSVGERYTTDMAITDTLIHELDVLRWLLGEDYASAQVVYPKKTRHASAHLADPQIVLLETASGVRIDVEIFVNCQYGYDIQCEVVGEQGIAKLPDPPAVGLKHAARQSVEIMTDWKERFIASYDVELQAFIDGVRQGALTGPSAWDGYAAAVAADACVRAQQSGAVEPIAMAERPAFYRG
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SOSB1_BOVIN
Sequence: MTTETFVKDIKPGLKNLNLIFIVLETGRVTKTKDGHEVRTCKVADKTGSINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNFSEPNPEYSAQQAPNKTVQNDSGPAAPQPPTGPPATSPASESQNGNGLSAPPGSGGGPHPPHTPSHPPSTRITRSQPNHTAAGPPGPSNNPVSNGKETRRSSKR
What is the function of this protein?
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint.  In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines.  The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability.  Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways (By similarity).
What are the official names of this protein?
SOSS complex subunit B1, Nucleic acid-binding protein 2, Oligonucleotide/oligosaccharide-binding fold-containing protein 2B, Sensor of single-strand DNA complex subunit B1, Sensor of ssDNA subunit B1, SOSS-B1, Single-stranded DNA-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the SOSS-B family. SOSS-B1 subfamily.
What are the subcellular locations of this protein?
Nucleus. Note=Localizes to nuclear foci following DNA damage. Foci formation is not cell-cycle dependent. Partial colocalization with RAD51 after ionizing radiation treatment (By similarity).
Protein: TNFB_MACMU
Sequence: MTPPERLFLSRVRGTPLHLLLLGLLLVLLPGAQGLPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATPTPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
What is the function of this protein?
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity).  In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.  Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
What are the official names of this protein?
Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane- associated.
Protein: KTHY_CERS1
Sequence: MGAQGFFLAVEGIDGSGKSGIVRSLAAHLGAEGRDVLVTREPGGTPEGEAIRGLVLAGADEAWDPMAELLLMTAARVQHVRRVIAPALAQGRVVISDRYAGSTLAYQGTGRGLSEAFIRTLHAEATGDLWPDLTLVLDLEAGIGLARSRRRLTGETLDEGRFESLDLAFHERIRAAFLAQAARDPGRHAVIDASGTPEEVQARACAALAPFLAQAPV
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: IBPB_SALPB
Sequence: MRNYDLSPLLRQWIGFDKLANALQNSGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLDIQLEGTRLTVKGTPEQPENEPKWLHQGLVMQPFSLSFTLAENMEVSGATFTNGLLHIDLTRNEPETIAPQRIAINERSALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM11_PYRAR
Sequence: MDLVNGLVALSLTHKELGVDELSKVANGVHRVCVSLRQPLFVLHTCNRVEAYLYNPPDEVVEIVKSGYAPYVEKVVERRGVDAARHLFRVAAGLESMLIGETDVLGQLEEAFDRQVRAGYTRELLKTVVERAIRVGKRVRTETGISRGPRGLGSLSILYVKEKIDLTNARVCVIGAGSVGRGLVKELIDAGARRLVVVNRSVEKAADLGVEVWPLSERSVERCLEDFDVVFTAVATFEPIIKSVPRDARVRIIVDMGMPRNTAAGLPVEVVTIDSLRDLADRFNAMRDAEIKKAEEIVEEELVALERLLRIRWVEEVSAKLLEYWFKIAEEEGERAGGLEAKIAARTTVKRTLLPVVNYLKKVAVSDIDEAYRIISVLRLSYGLKDL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase 1, GluTR 1.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: MURG_ACIBS
Sequence: MTDSQQSKPKHVMMMAAGTGGHVFPALAVAKQLQQQGCQVSWLATPIGMENRLLKDQNIPIYQIDIQGVRGNGVIRKLAAPFKILKATFSAMRYMKQLKVDAVAGFGGYVAGPGGLAARLLGIPVLIHEQNAVAGFTNAQLSRVAKVVCEAFPNTFPASEKVVTTGNPVRREITDILSPKWRYDEREQAGKPLNILIVGGSLGAKALNERLPPALKQLQVPLNIFHQCGQQQVEATQALYADAPANLTVQVLPFIEDMAKAYSEADLIICRAGALTVTEVATAGVAAVFVPLPIAVDDHQTANAKFLADVGAAKICQQSTMTPEVLNQLFTTLMNRQLLTEMAVKARQHAQPNATQHVVGLIQKM
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.