PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_KOSOT
Sequence: MRKAMFGKRERWVFGKVIEPLEIPNLIEIQLKSFKWFLEEGLLDVLKKYSPIKSQIQRPDSRKNEKGFSLEFVRTRIGNPKYNIQECKDKGLTYSVPLYVTVRITDLYSGEIKEEEAFFGYLPYMTDNASFIINGAERVIVNQLVRSPGVYFVDEPTKASSGSLPILVAHFLPVKGAWLEILLNPNKKVLQVRIDRRRKMNLFLLLKTLGYEDDLELLDLFVHDVDANDEYVLLEHVGSIILSDVKTRNELIAERGAVLTEALAKKIAESDVDVIKLPMPIAMSTLKAFHRTYGENIKSEDAYIEIFRKLRPGEIPRINAAKNYLHNLYFSPDRFDFSEVGRHKINSRLRKVYKEYLKEVKKTEVPEDIEYAEESTVLTELDIVLAARHLAQLESHPELLDTKDHLGNKRVRTVGELMQNEFEKAFVKIHKLLEEKLTIYTSFDKVTVQNLVNVRTLMTTLHQFFATSQLSQFMDQVNPLAELTHKRRLSAIGPGGLKREHARFEVRDVHHSHYGRMCPIETPEGANIGLMTSLSTYATIDKYGFLLTPYRKVKNGKVTDEIVYLAADEEELYNIAQSTIEVDDNGNIVESVVEVRHAGEIKYVEKEKVDLMAISPKQIVSVSTSLIPFLEHDDANRALMGSNMQRQAVPVIKPEAPIVGTGVEAIAARDSGYVVLAKHRGIVKKVDSRKIIIERIDEDGNPILSESGEPIQDVYTLHKFIRTNQDTTINQRPIVSQGETVEKGDPIADGPSTDMGELALGKNIFVAFLPWEGYNFEDAILVSQELLEEETFTTIHIEMYETVARDTQLGPEEITADIPNVSKELLKNLDENGIVRVGAYVSSGDILVGKVTPKGESDTTPEEKIIRSVFGDRGRDVKDTSLRVPHGVEGRVIDVKVFDKEEISELGSGVNKLVKVYVACRKPLDVGDKLAGRHGNKGVVSNIIPKEDMPFLPDGTPVQIVLSPLGVPSRMNVGQVLETHLGWLGQLTNRYFATPIFDGAKEDEIMEELYKARKAAGIDVGDSKKEKNGKVLLRDGRSGLPFDYPVVVGVMYMLKLVHIAKDKIHARSTGPYSLIHQQPLGGKAHFGGQRFGEMEVWALEAHGAAHTLNEVLTVKSDDIKGRNEVYKAILKGLNVPGPGIPESFKVLIKELQGLALDIRVYDQNGNELDVDKL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: INHA_HORSE
Sequence: MVPPLPLLLLLLLVPQGGHGCQGSELDREIVLAKVRALFLDALGPPAVTGEGGDPGVRRLPRRHALGGFARRGSEPEEEDVSQAILFPASGSRCEDEPAAGELAQEAEQGLFTYMFRPSQHMRSRQVTSAHLWFHTGLDRQGTAASNSSEPLLGLLALSSGGPMAVPVTLGQAPPCWAVLHLAASALPLLTHPVLVLLLRCPLCSCSARPEATPFLVAHTRARPPSGGERTRRSTPPLPWPWSPAALRLLQRPPEEPAAHANCHRAALNISFQELGWDRWIVHPRSFIFHYCHGGCGLSAPPDLPLPVPEVPPTPIQPLSLVPGAQPCCAALPGTMRPLRVRTTSDGGYSFKYEIVPNLLTQHCACI
What is the function of this protein?
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland.  Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.  Inhibins appear to oppose the functions of activins.
What are the official names of this protein?
Inhibin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: 6PGL_AGGAC
Sequence: MNYITFPTAQHAVEKIAQEFVIYSQLNHPAHISLSGGSTPKLLFKTLAQSPYAEQINWRNLHFWWGDDRMVSPSDPESNYGEVQKLLFDHIQIPAENIHRIRGENEPHFELKRFQAELSAVISDGVFDWIILGMGADGHTSSLFPHQTNFDDENLAVIAKHPESGQIRISKTAKLIEQAKRITYLVTGEGKAEILKEIQSTPAENLPYPAAKIYAKNGVTEWYLDKDAAKLL
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: HTPG_XANAC
Sequence: MTVETDKQTLGFQTEVKQLLQLMIHSLYSNKEIFLRELVSNAADAADKLRFEALVKPELLEGSGELRIRVDYDKDARTVTIDDNGIGMSREDAVSHLGTIAKSGTADFLKHLSGDQKKDANLIGQFGVGFYSAFIVADQVDVYSRRAGLPASEGVHWSSRGEGEFEIASVDKPERGTRIVLHLKEGEESFADGWTLRGILKKYSDHIGLPIEMRKEHYGEAADKPAEPEWEAVNRASALWTRPKSEIKDEEYQEFYKHVAHDAGNPLAWSHNKVEGKLEYTSLLFVPGRAPFDLYHRDSAKGLKLYVQRVFIMDQAEQFLPLYLRFIKGVVDSSDLSLNVSREILQSGPVVDSMKSALTKRSLDMLEKLAKDKPDDYATFWRNFGQALKEGPAEDYANREKIAGLLRFSSTHDTTGAQSVGLADYVGRLADGQDKLYYLTGESYAQIKDSPHLEVFRKKGIEVLLLTDRIDEWLMSYLTEFDGKSFVDVARGDLDLGKLDSEEDKKAQEEVAKSKEGLASRIKAALGDDVAELRVSHRLTDSPAILAIGQGDLGLQMRQLLEASGQAVPESKPVFEFNPTHPLIEKLDAEQDMDRFGDLSRVLFDQAALAAGDSLKDPAAYVRRLNKLLLELSA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUAC_BOVIN
Sequence: MELLQVLKRGLQQVSGHGGLRGYLRVLFRANDVRVGTLVGEDKYGNKYYEDNKQFFGRHRWVIYTTEMNGKNTFWDVDGSMVPPEWHRWLHCMTDDPPTVKPPTARKFIWTNHKFNLSGTPQQYVPYSTTRKKIQEWVPPSTPYK
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12, Complex I-B17.2, CI-B17.2, CIB17.2, NADH-ubiquinone oxidoreductase subunit B17.2.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA12 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: Y1242_SYNY3
Sequence: MRALLIYPLFPPTFWSYEKILELVGRKVLLPPLGLITVAGILPQEWEFKLVDRNVRNVTEAEWDWAEVVIISGMIVQRDDMVENIKEAKAHGKLVAVGGPFATSVPDEVQNAGADFLILDEGEITLPLFVEALERGETAGIIRAQEKPDVTTTPIPRYDLLELDAYDSMSVQFSRGCPFQCEFCDIIVLYGRKPRTKEPAQLLRELDYLYELGWRRSVFMVDDNFIGNKRNVKLLLKELKVWQEEHQYPFRFNTEASVDLADDQELMDLMVECYFDAVFLGIETPDEESLEFTKKFQNTRNSLADSVDKIIKAGLRPMAGFIIGFDGEKQGAGDRIVRFAEQTAIPTTTFAMLQALPNTALWHRLKRENRLLDESKGNINQTTLMNFIPTRPLEDIANEYVEAFWELYDPHGYLDRNYRCFLKLGAPKCKTAFKLPNLVDLKALAIVIWRQGVKRDTRFRFWHHAFGILRHNPAVFEHYITLCAHNEHFLQYREIVRQEIGEQLRDYLSRQQQDKVEETVLSPTAIAAETEKVLAS
What are the official names of this protein?
Uncharacterized methyltransferase sll1242, ORF N.
Protein: DNAA_SYNS9
Sequence: METGDELWTKVRKGLQDKLSKPTFETFIRPTGCSSFSNGELKLLAPNPFTSIRLREQLLPTIAEMATSISGRSVQVTVLAETALPKSEFVADAAAVELTDVSEPRRESAPARPSGQRRYLPALNPRYVFGRFVVGQNSRMAHAAALAVAEAPGREFNPLFICGGVGLGKTHLMQAIGHYRLEIDPGARVAYVSTETFTNDLIQAIRKDGMQAFRDRYRAADLILVDDIQFIEGKEYTQEEFFHTFNALHEAGRQVVIASDRPPSQIPRLQQRLISRFQMGLIADIQSPDLETRMAILQKKAEQERMALPRDLIQYIAGRFTSNIRELEGALTRAVAFASITGLPMTVESVAPMLDPTGQGVAVSPQQVIEKVSEVFDVTAEEMCSSTRRRAVSQARQVGMYLMRQGTDLSLPRIGDTFGGKDHTTVMYAIEQIEKKLASDPKLAGQVQKVRDLLQIDSRSKR
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_STAES
Sequence: MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTGEHEAVELRDGDKSRYLGKGVTKAVENVNEMIAPEIVEGEFSVLDQVSIDKMMIQLDGTHNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDAPIAFQEFMILPVGAESFKESLRWGAEIFHNLKSILSERGLETAVGDEGGFAPRFEGTEDAVETIIKAIEKAGYKPGEDVFLGFDCASSEFYENGVYDYTKFEGEHGAKRSAAEQVDYLEELIGKYPIITIEDGMDENDWEGWKQLTDRIGDKVQLVGDDLFVTNTEILSKGIEQGIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDELYETAKFEGIKSFYNLDK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: IXTPA_ALBFT
Sequence: MKIVLASNNRGKLAELRAMLAPLGFELITQGELGIPEAPEPYHTFVENALAKARHASAHSGLPALADDAGLCVDAFGGLPGVQTAFYATRFGYEKGDDNNVRALLEQMRDVDNRRAALVSTLVAVRSEQDPEPLIAVGRVVGEIARAPVGSHGFGFDPVMLIPEFGQTFAQLPVEVKNANSHRGRAARAMLALMRERWL
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: SKG6_YEAST
Sequence: MYHTHMHESLISVTSTVSVSDASYAYARLTRRDDSDSSSSSASSTKNSKSAECTGSKQQCQLPTDSSHSTSVTVGVAVAVPVGVIIIVLAVILCIVYRRSKKEAEEDNDPDFEGDSEFLPTMKDYSPGINHLYSSDSQQDFMEKTLQQPPSDPFVGSMHSSKYNVRSATPPAIGRSWYVDPFQLPQESNDSNSLRDFAMRVQEDGLGGYKVAAESRNASQTSLHPDNFSNCTPIRASSRFQESESFRSHGSPIHNNQLSRGSATEGANKQFTFPNEDNDSSSVSEEAEVLNESNESASNDAFEFELDNSSEKTHERNLRFGKDDDNYELQDIREAEHMNDRSSSKSQDDDYYVSLLSPNEEEDIKRMKSIYQVYLDRAKTMKKEEDKADNANDISQEENRVDNIVQNPLPSIKINNNDNIDNNEVPEAKHLVKEALPLNNTNLAEYGPEMAQSQKQYPVQDTLTVNDTEAAPSNRIASSIYSEAIQPLNYQDQYQQQEQSPVYNGHTQYPGNGYSGNPQQQGYTAQFVQNPQWYGVPTPQQQQHNHPQTLETIGELPTPAYLAQSASSHSLTSFKRPNKQQLLQLQTARLNGTALNPVDHPEMFYSPTNDAYYAPQQQGQYMKFNENGAVPSPYQLRQSVVMTNPSDLTAKPSYKPAGSFRSVSATNSRNNSLTTQNNIYLQQQQQQLYNSRVSGILEETDVVQPPSVGGILPHSGSQDDLRKQLGSSHNYTVN
What is the function of this protein?
May be involved in the polarity establishment process.  Suppresses the lethality of KEX2-GAS1 double null mutant when overexpressed.
What are the official names of this protein?
Protein SKG6, Suppressor of lethality of KEX2-GAS1 double null mutant 6.
What is the protein family that this protein belongs to?
Belongs to the SKG6/TOS2 family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Note=Localizes primarily to the growing sites, such as an incipient bud site in the cells with emerging buds, a bud tip in small- or medium-budded cells, or a cell periphery in large-budded cells.
Protein: SODM_CORDI
Sequence: MTYALPELDYAYDALEPHIAAEIMELHHSKHHANYVNGANAALEKLQKARENGEIGAVVTALSKDLAFNLGGHTNHSIFWKNLSPNGGGEPTGALAEAIAKEFGSFEKFKDHFSAAALGLQGSGWAVLGYDHIGGRLVIEQLTDQQGNISANLTPLLMLDMWEHAFYLQYKNVKADYVKAVWNVFNWDDVAARFEAATK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: CCME_LEPCP
Sequence: MKPRHKRLAIAGGVLVAVGAIATLVLNAFQSNLVFFYSPSQVVAKEVPDGRTFRLGGMVEDGSVKREGVMVSFVVTDTVQKVPVRFEGILPDLFKEGKGVVAQGKVEGGTFIAKEVLAKHDENYMPPEAAEALKRAKEGGQMQSSQAATGDPR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: S35G2_RAT
Sequence: MDTSPSKKYPIKKRVKIHPNTVMVKYTSHYPQPGEDGYEEINEDYGRFMEENPKKSLLSEMRRKGRTLFGTMDTQPPRSEDPRASSRGQFQSFAEKNIFQSRKMWLVLFGSALAHGCVALITRLVSDRSKVPSLELIFIRSVLQVLSVIVVCYYQEAPFGPSGYRLRLFLYGVCNVISITCAYTSFSIVPPSNGTTMWRATTTVFSAVLAFLLVDEKMAYVDMATVVCSILGVCLVMIPNIADEDNSLLNVWKEAFGYTMTVMAGLTTALSMIVYRSIREKISMWTALFTFGWTGTIWGLSTMFVLQEPIIPLDGETWSYLIAICICSTVAFLGVYYALDKFHPALVSTVQHLEIVVAMVLQLLVLHIFPSVYDVFGGVIIMISVFVLAGYKLYWRNVRREDYQEILDSPIK
What are the official names of this protein?
Solute carrier family 35 member G2, Transmembrane protein 22.
What is the protein family that this protein belongs to?
Belongs to the SLC35G solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: CPLX1_BOVIN
Sequence: MEFVMKQALGGATKDMGKMLGGDEEKDPDAAKKEEERQEALRQEEEERKAKYAKMEAEREAVRQGIRDKYGIKKKEEREAEAQAALEANSEGSLTRPKKAIPPGCGDAAEEEDESILDTVIKYLPGPLQDIFKK
What is the function of this protein?
Positively regulates a late step in synaptic vesicle exocytosis.  Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse.  Also involved in glucose-induced secretion of insulin by pancreatic beta-cells (By similarity).
What are the official names of this protein?
Complexin-1.
What is the protein family that this protein belongs to?
Belongs to the complexin/synaphin family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Perikaryon. Presynapse. Note=Enriched at synaptic-releasing sites in mature neurons.
Protein: MURB_SHEON
Sequence: MSFPYSLKSFNTFGVTQSCLSLIEVRSKAELQAICLPLYQSKQPMLVLGGGSNIVFTDDFNGTVVRVLSKGISVTEDVSYFYLEIEAGENWHELVEFTLNNHMAGLENLALIPGTVGAAPIQNIGAYGVELCDICHWVEYLDLDSGLLLRLSVDECEFSYRESIFKGRLRDKAVITAVGLRLPKTWQPRLAYGPLQSFAADTVTPRDIFERVCEVRSEKLPDPHILGNAGSFFKNPIISAAAYVELAQRFPNIVGYAQANGDVKLAAGWLIEHAGLKGFVLGNAGVHAKQALVLVNLGNATGQDICRLALHVIARVHDVFGVMLEAEPRIMGLNGETSLHV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SURE_SALG2
Sequence: MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFDNGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLNGYQHYDTAAAVTCALLRGLSREPLRTGRILNVNVPDLPLAQVKGIRVTRCGSRHPADKVIPQEDPRGNTLYWIGPPGDKYDAGPDTDFAAVDEGYVSVTPLHVDLTAHSAHDVVSDWLDSVGVGTQW
What is the function of this protein?
Nucleotidase with a broad substrate specificity as it can dephosphorylate various ribo- and deoxyribonucleoside 5'-monophosphates and ribonucleoside 3'-monophosphates with highest affinity to 3'-AMP.  Also hydrolyzes polyphosphate (exopolyphosphatase activity) with the preference for short-chain-length substrates (P20-25).  Might be involved in the regulation of dNTP and NTP pools, and in the turnover of 3'-mononucleotides produced by numerous intracellular RNases (T1, T2, and F) during the degradation of various RNAs.
What are the official names of this protein?
5'/3'-nucleotidase SurE, Exopolyphosphatase, Nucleoside monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_BACHK
Sequence: MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICHAVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYDRFDFHIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRF_CHRSD
Sequence: MSPDLDTPLIIALDYPRLDQALAMAERLDPSRCRVKVGKELFTRTGPRVLEALHGLGFEVFLDLKFHDIPNTVAGAVEAAADHGVWMVNVHAGGGRRMMEAARERLERRRLGTHLIAVTVLTSMERDDLIEVGVEAEPLSQVERLARLAQQSGMAGVVCSAQEAAALRATCGDDFLKVTPGIRPRASSADDQRRTLTPGEAMAAGSTHLVVGRPVTQAPDPMAALATIERELAEPS
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: GSTM1_DERPT
Sequence: MSQPILGYWDIRGYAQPIRLLLTYSGVDFVDKRYQIGPAPDFDRSEWLNEKFNLGLDFPNLPYYIDGDMKMTQTFAILRYLGRKYKLNGSNDHEEIRISMAEQQTEDMMAAMIRVCYDANCDKLKPDYLKSLPDCLKLMSKFVGEHAFIAGANISYVDFNLYEYLCHVKVMVPEVFGQFENLKRYVERMESLPRVSDYIKKQQPKTFNAPTSKWNASYA
What are the official names of this protein?
Glutathione S-transferase, GST class-mu, Major allergen Der p 8, P dp 15.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATAD3_RAT
Sequence: MSWLFGIKGPKGEGTGPPLPLPPAQPGAESGGDRGAGDRPSPKDKWSNFDPTGLERAAKAARELEHSRHAKEALNLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLNEETRQHQARAQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEARARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLLAVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILSPSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGREGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFMLVLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGKKCSEVAQLTAGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLKVERPDSEASKPPHPSLLSC
What is the function of this protein?
Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level.  May play an important role in mitochondrial protein synthesis.  May also participate in mitochondrial DNA replication.  May bind to mitochondrial DNA D-loops and contribute to nucleoid stability.  Required for enhanced channeling of cholesterol for hormone-dependent steroidogenesis.  Involved in mitochondrial-mediated antiviral innate immunity.
What are the official names of this protein?
ATPase family AAA domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: Y1853_RHIEC
Sequence: MKITWLGHSAFRIETSKSKILLDPFLSHNASFSGQDIKDVSAGITHILLTHGHGDHVGDTVALAKETGAVVLANADLAAWLGSKGVDRIEMGNTGGTVTFGGFSATFTNALHSSAQITEDGVSHALGNANGLMLHFDDEASIFAMGDTDIFSDMALINELHQPDIGFVPIGDRFTMGGAVAALACQRYFSFKTAIPCHYGTFPIIDQTADKFVAGMEGSKTQARAMKPAESLSI
What are the official names of this protein?
UPF0173 metal-dependent hydrolase RHE_CH01853.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: RSMA_STRPM
Sequence: MIIKRREYMRIADYSVTKAVLDRHGFTFKKSFGQNFLTDTNILQKIVDTAEIDQNVNVIEIGPGIGALTEFLAENAAEVMAFEIDDRLVPILADTLRDFDNVQVVNQDILKADLQTQIKQFKNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRISAEPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRDQPLIEVKDEDFFFRVSRLSFVHRRKTLWNNLTSHFGKSEDIKTKLEKGLALADIKPSIRGEALSIQDFGKLADALKEVGL
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IGA1_STRSA
Sequence: MKKFLGEKQTRFAFRKLAVGLVSAAISSLFFVSIVGVDSVQAQEKLNVHYKYVTDTEITPQEKELIVSGVPRMPEGNEETYYLVYRLNSNAGAKTLPNTGDNNSNTMMAAGLLLTTIGLVVFAVSKRKVQSKFLLTVLVGASVGGGLILSVDALENGSLLQYNAEYQVSAGESLPSPGEISGYTYVGYIKDESIKKLLDNKIPDNQQNANVDKEALNQNKKLDYSVSFDKNGLKNQTVGVNTIEPQDEVLSGRVAKPELLYKETSIETEIAYGEQIQENPDLAEGTVRVKQEGKPGRKIEVVRIFTVDNAEVSREVLSTKIEEATPKIVEKGTKKLEAPSEKPVTSNLVQPEQVAPLPEYTGVQSGAIVEPEQVASLPEYSGTLSGAIVEPEQIEPEIGGVQSGAIVEPEQVTPLPEYTGTQAGAVVSPEQVAPLPEYTGTQSGAIVEPAQVTPLPEYTGVQSGAIVKPAQVTPLPEYTGTQSGAIVEPEQVTPSPEYTGVQAGAIVEPEQVASLPEYTGSQAGAIVEPEQVEPPQEYTGNIEPAAPEAENPTEKAQEPKEQKQEPEKNIELRNVSDVELYSLADGKYKQHVSLDAIPSNQENYFVKVKSSKFKDVFLPISSIVDSTKDGQPVYKITASAEKLKQDVNNKYEDNFTFYLAKKAEREVTNFTSFSNLVQAINNNLNGTYYLAASLNANEVELENGASSYIKGRFTGKLFGSKDGKNYAIYNLKKPLFDTLSAATVENLTLKDVNISGKTDIGALANEANNATRINNVHVDGVLAGERGIGGLVWKADNSKISNSSFKGRIVNSYETKAPYNIGGLVGQLTGINALVDKSKATITISSNADSTNQTVGGLAGLVEKDALISNSYAEGNINNVKRFGSVAGVAGYLWDRDSSEERHAGRLHNVLSDINVMNGNAISGYHYRGMRITDSYSNKDNRVYKVTLEKDEVVTKESLEERGTILDVSQIASKKSEINSLSAPKVETLLTSTNKESDFSKVKDYQASRALAYKNIEKLLPFYNKATIVKYGNLVKEDSTLYEKEILSAVMMKDNEVITDIASHKEAANKLLIHYKDHSSEKLDLTYQSDFSKLAEYRVGDTGLIYTPNQFLQNHSSIVNEVLPDLKAVDYQSEAIRNTLGISSGVSLTELYLEEQFAKTKENLANTLEKLLSADAVIASENQTINGYVVDKIKRNKEALLLGLTYLERWYNFNYGDVNVKDLVMYHMDFFGKGNVSPLDTIIELGKSGFNNLLAKNNVDAYNISLANNNATKDLFSTLANYREVFLPNKTNNQWFKEQTKAYIVEEKSAIDEVRVKQEQAGSKYSIGVYDRITSDTWKYRNMVLPLLTMPERSVFVISTISSLGFGAYDRYRNNEHRAGAELNKFVEDNAQETAKRQRDHYDYWYRILDEQGREKLYRNILVYDAYKFGDDTTVDKATVEAQFDSSNPAMKYFFGPVGNKVVHNKHGAYATGDSVYYMGYRMLDKDGAITYTHEMTHDSDNEIYLGGYGRRSGLGPEFFAKGLLQAPDHPDDATITVNSILKYDKNDASEKSRLQVLDPTKRFQNADDLKNYVHNMFDVIYMLEYLEGMSIVNRLSDVQKVNALRKIENKYVRDADGNDVYATNVIKNITMADAQKLNSFNSLIENDILSAREYKNGDVERNGYHTIKLFSPIYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEDDAKQNGKTISIYGKTRGLVTDDLVLRKVFNGQFNNWTEFKKAMYEERKNKFDSLNKVTFDDTRQPWTSYATKTISTVEELQTLMDEAVLQDANDNWYSWSGYKPEYNSAVHKLKKAVFKAYLDQTKDFRKSIFENQK
What is the function of this protein?
Zinc metalloproteinase which cleaves human immunoglobulin A1 (IgA1) in the hinge region.
What are the official names of this protein?
Immunoglobulin A1 protease, IgA1 protease, IgA-specific zinc metalloproteinase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M26 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Membrane; Multi-pass membrane protein. Secreted, cell wall; Peptidoglycan-anchor.
Protein: SODM_HAEIN
Sequence: MSYTLPELGYAYNALEPHFDAQTMEIHHSKHHQAYVNNANAALEGLPAELVEMYPGHLISNLDKIPAEKRGALRNNAGGHTNHSLFWKSLKKGTTLQGALKDAIERDFGSVDAFKAEFEKAAATRFGSGWAWLVLTAEGKLAVVSTANQDNPLMGKEVAGCEGFPLLGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDFVAERFEQKTAHSNCAK
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.