PharMolix/UniProtQA huggingface dataset:
Protein: MIMB_MYCS2
Sequence: MADSHKINFDPVDIEMEVREDENILDAAFRQGIHLMHGCREGRCSACKSYVLDGEIQMESYSTFACNDAEVDEGYVLLCRSHAFSDCTIELLNFDEDELLGGIPIQDVRTQVQAVEPKTRDIVSLRLKPIEPGKFDFKPGQYADLHIPGTDEHRSFSMATTQSRSDEVEFLIKKYPGGKFSALLDGHIQVGDEIALTGPYGSFTLKDGHVLPVVCIGGGAGMAPILSLLRHMNETENSRPARFYYGARTPADLFYLDEILELGKGIKDFRFIACLSESADGEVPGRVTVEEGMVTDVVARHETAIAKTEVYLCGPPPMVDAALMFLDANCVPKDQVFYDSFTSPIFDQ
What is the function of this protein?
Reductase component of the propane 2-monooxygenase multicomponent enzyme system which is involved in the degradation of propane via the O2-dependent hydroxylation of propane.  Reductase catalyzes the transfer of electrons from NADH or NADPH to monooxygenase (Probable).
What are the official names of this protein?
Propane 2-monooxygenase, reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: BSPRY_RAT
Sequence: MSSDVSGTESGSESGPESVPEPVPEPGPEPESEPGPGPAPGPGPGPAPGPGPGLGREPGQRYQPCQLCPEHGKPLSWFCLSERRPVCATCAGFGGRCHRHRIRRAEEHAEELRNKIVDHCEKLQLQSAGITKYVAEVLQGKNQKAMIMANATREVIIQRLSLVRCLCESEEQRLLEQVHSEEERAHQCILTQRAHWDDKLRKLDSLRTSMVDMLTHLNDLQLIQMEQEILERAEEAEGILEPQESEKLSFNEKCAWSPLLTQLWATSVLGSLSGMEDVLIDERTVGPLLNLSEDRKTLTFNAKKSKVCSDDPERFDHWPNALAVNAFQTGLHAWAVNVKHSCAYKVGVASAQLPRKGSGSDCRLGHNAFSWVFSRYDQEFCFSHNGNHEPLALLRCPTQLGLLLDLQAGELIFYEPASGTVLHIHRESFPHRLFPVFAVADQVISIVC
What is the function of this protein?
May regulate epithelial calcium transport by inhibiting TRPV5 activity.
What are the official names of this protein?
B box and SPRY domain-containing protein, Zetin-1.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein.
Protein: TBX3_RAT
Sequence: MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSNLKDLCPSEAESDAEAESKEEHGPEACDTAKISTTTAEEPGRDKGSPATRAQLFPAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADEHRSPGREGPVSAKVDEARALPAKDAFAPLSVQTDATAHLTQGPLPGLGFAPGLAGQQFFNGHPLFLHPGQFAMGGAFSSMAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNSMRPRLRYSPYSIPVPVPDSSSLLATALPSMASAAGPLDGKSAVLAASPASVAVDSGSELNSRSSTLSSGSVSLSPKLCSEKEAATSELQSIQRLVSGLEAKPDRSCSGSP
What is the function of this protein?
Transcriptional repressor involved in developmental processes (By similarity).  Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes (By similarity).  Probably plays a role in limb pattern formation (By similarity).  Required for mammary placode induction, involved in maintenance of the mammary buds during development and branching morphogenesis in embryonic and adult glands; partially redundant with TBX2 (By similarity).  Involved in modulating early inner ear development, acting independently of, and also redundantly with, TBX2 in different subregions of the developing ear (By similarity).  Acts as a negative regulator of PML function in cellular senescence (By similarity).
What are the official names of this protein?
T-box transcription factor TBX3, T-box protein 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLMM_LYSSC
Sequence: MGKYFGTDGVRGVANSELTPEFAFKLGRIGGYVLTKDATDRPKVLIGRDTRISGEMLEGALVAGLLSIGVEVMRLGIISTPGVAYLTRIMSADAGVMISASHNPVADNGIKFFGPDGFKLTDAQEEEIEVLLDAQEDTLPRPIGADLGSVSDYFEGGQKYIQYLKQTVDEEFDGIHVALDCAHGATSSLATHLFADLEADISTMGSSPNGLNINDGVGSTHPEGLAKFVLEKDADVGLAFDGDGDRLIAVDENGKIVDGDQIMFIIGKYLNAVGRLKKQTIVSTVMSNMGFYKAVEDNGMQSIQTAVGDRYVVEEMRANDYNLGGEQSGHIVFLDFNTTGDGLLTGIQLVNIMKATGKKLSELAAEMKIYPQRLVNVRVTDKHAVTENTKVAAVIAEVEAAMAGNGRVLVRPSGTEPLVRVMVEAATETACERFVERIADVVRAEMGLTD
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RNH_AFIC5
Sequence: MSEPQRPHVVIFTDGACSGNPGPGGWGAILRFGEIEKELKGGENPTTNNRMELLAAISALEALKRSAIVDLTTDSQYVRQGITSWIFNWKKNGWRTSDKKPVKNVDLWQRLDAALKPHEVRWHWIKGHAGHAENERADELAREGLAENR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJLD_BACSU
Sequence: MSKHIVILGAGYGGVLSALTVRKHYTKEQARVTVVNKYPTHQIITELHRLAAGNVSEKAVAMPLEKLFKGKDIDLKIAEVSSFSVDKKEVALADGSTLTYDALVVGLGSVTAYFGIPGLEENSMVLKSAADANKVFQHVEDRVREYSKTKNEADATILIGGGGLTGVELVGELADIMPNLAKKYGVDHKEIKLKLVEAGPKILPVLPDDLIERATASLEKRGVEFLTGLPVTNVEGNVIDLKDGSKVVANTFVWTGGVQGNPLVGESGLEVNRGRATVNDFLQSTSHEDVFVAGDSAVYFGPDGRPYPPTAQIAWQMGELIGYNLFAYLEGKTLETFKPVNSGTLASLGRKDAVAIIGANSTPLKGLPASLMKEASNVRYLTHIKGLFSLAY
What are the official names of this protein?
NADH dehydrogenase-like protein YjlD, Glucose starvation-inducible protein 5, GSI5.
What is the protein family that this protein belongs to?
Belongs to the NADH dehydrogenase family.
Protein: TXD12_RAT
Sequence: MSLRFGATCLLSFSFLLLITSSDGRTGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPRDEDFSPDGGYIPRILFLDPSGKVRPEIINESGNPSYKYFYVSAEQVVQGMKEAQVRLTGDAFREKHFQDEL
What is the function of this protein?
Protein-disulfide reductase of the endoplasmic reticulum that promotes disulfide bond formation in client proteins through its thiol-disulfide oxidase activity.
What are the official names of this protein?
Thioredoxin domain-containing protein 12.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: TVA16_HUMAN
Sequence: MKPTLISVLVIIFILRGTRAQRVTQPEKLLSVFKGAPVELKCNYSYSGSPELFWYVQYSRQRLQLLLRHISRESIKGFTADLNKGETSFHLKKPFAQEEDSAMYYCALS
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 16.
What are the subcellular locations of this protein?
Cell membrane.
Protein: AROB_ACIAD
Sequence: MQTLHVELGDRRYPIFIGSQLNPQNLLAPYIKGRQVMIVTNTTLEQLYLQHYQDALHALDKQVAVCVLPDGEKYKNIEHLNLIFDALLKAGFNRDCTVLALGGGVIGDMAGFAAASFQRGVYFVQIPTTLLSQVDSSVGGKTGINHPLGKNMIGAFKQPEVVMADMSQLKTLPPRELSAGLAEVIKYALLGDIEFLGWLETHMDGLIAGDETLLAEAVYRSCAHKARIVANDEKEQGERALLNLGHTFGHAIESYLGYGEWLHGEAVATGMVMAADLSHRLGWISSGDLERTKKIIQRANLPISCPPIPLDEFLSYMSHDKKVLNGQLRLVLLQQLGQAIITKTFDVEMMKAAILANQASHT
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURB_LACDB
Sequence: MKLYDLKAQGLDLQENIPLSRYTFTQTGGPAEYLAFPKTLAELKELLAAAKEDQLPITVIGNASNLIIRDKGIKGLVIILTEMKEIKVEADKVHAQAGARIIDTSFAAGEAGLSGLEFAAGIPGSVGGAVFMNAGAYGGETKDCLESATVVTRDGEVKTYTNAELHFSYRHSLLQENDEIVIAATFALKAGDKATILDQMNYLNALRSYKQPLEYPSCGSVFKRPTGHFVGPMLIKAGLQGKQIGGAQVSTKHAGFIVNKGGATATDYLNLIHYIQKTIKEKDGIALQTEVRIIGEE
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_CARHZ
Sequence: MPREYPLERTRNIGIMAHIDAGKTTTTERILFYTGKVHKMGEVHDGAATMDWMVQEQERGITITSAATTCFWKNHRINIIDTPGHVDFTVEVERSLRVLDGAVAIFCAVGGVEPQSETVWRQADKYGVPRIAYVNKMDRMGANFFEVVRQIKERLGANPVPIQLPIGNEDTFQGVIDLIENKAIIYTDDLGTQLAEAEIPAEMLDLVAEYREKVMEAAAEADEELMLKYLDGEELTPEEIRAGLRKATIAVKVVPVLCGSSFKNKGVQPLLDAIVYYLPSPVDIPAVRGINPETGDEDFRKASDSEPFAALAFKIMADPYVGKLTFFRVYSGVLKAGSYVLNSTKGKKERIGRLLRMHANHREEIDEVCSGDIAAAVGLKDTHTGDTICDEKHPIVLESMEFPEPVINVAIEPKTKQDQEKMSIALQRLAEEDPTFKMWTDQETGQTIIAGMGELHLEIIVDRLMREFKVEANVGKPQVAYKETVRGTAKAEGKYIRQTGGRGQYGHVWIEIEPLEPGKGYEFVNKIVGGVIPKEYIPAVDAGVREALESGVLAGYPVIDVRVTLFDGSFHEVDSSEMAFKIAGSMAAKQAVLKANPVLLEPIMKVEVVVPEEYMGEVIGDLNSRRGRIEGMEARNNMQVVRGYVPLAEMFGYATDLRSKTQGRGTYTMHFSHYEEVPKNLADQIIQKRQGK
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_BRUA4
Sequence: MSFLDSYRKKTQMPSTDEALPGRAQPIPTSTTHFVNGRPLKGPWPEGYKQVLFGMGCFWGAERLFWQVPGVYVTAVGYAGGVTPNPTYEETCTGLTGHAEVVLVVYDPKVVSLDELLTLFWEEHDPTQGMRQGNDIGTTYRSVIYTFDKTDRDVAEKSREAYSQALAGRGLGPITTEIEDAPELYYAEDYHQQYLAKNPNGYCGLRGTGVSCPIPLAQ
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: TRPC_PSEA8
Sequence: MSVPTVLQKILARKAEEVAERRARVNLAEVERLARSADAPRGFANALLERAKRKEPAVIAEIKKASPSKGVLREHFVPAEIARSYEAGGAACLSVLTDVDFFQGADAYLKEARAACALPVIRKDFMIDPYQIVEARAIGADCILLIVSALDDVLMAELAATAKSVGLDVLVEVHDGTELERALKTLDTPLVGINNRNLHTFEVSLETTLDLLPEIPRDRLVVTESGILNRADVELMEVSEVYAFLVGEAFMRADDPGLELKRLFFQERGGVVLGADPD
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: ARGP_YERPA
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENLFGQPLLVRTVPPRPTEQGQKLLALLHQVELLEEEWLGNDNGVDTPLLLSLAVNADSLATWLLPALKPVLADLPIRLNLQVEDETRTQERLRRGEVVGAVSIQPQPLPSCLVDQLGALDYLFVASKAFAERYFPNGVTRSALLKAPAVAFDHLDDMHQAFLQQNFDLSPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLLQRRMLFWHRFAPESRTMRKVTDALLSYGRQVLRQDSFIGQ
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: RL30_THET2
Sequence: MPRLKVKLVKSPIGYPKDQKAALKALGLRRLQQERVLEDTPAIRGNVEKVAHLVRVEVVE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: EFG_STRPJ
Sequence: MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAVAETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTDEEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLQSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEKAKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQEEIIKKNKGED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_NEIG2
Sequence: MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEELQASRNSISKQIGALKGQGKHEEAQAAMDQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPPGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQFMLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQYLIPTAEVTLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVHPEKSYGALEEMVGHAENILKALELPYRVITLCTGDMGFSAAKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAALQPYMGGVTKLEVK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTD_ECO55
Sequence: MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVEQACRAARAAFPRWARLSLAERQVVVERFAGLLERNKGELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAWQQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAILMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR
What is the function of this protein?
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.
What are the official names of this protein?
N-succinylglutamate 5-semialdehyde dehydrogenase, Succinylglutamic semialdehyde dehydrogenase, SGSD.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. AstD subfamily.
Protein: SUI1_SPOST
Sequence: MSDLDIQIPTAFDPFSEANAGDSGAAAGSKDYVHVRIQQRNGRKSLTTVQGLKKEFSYNKILKDLKKEFCCNGTVVQDPELGQVIQLQGDQRKNVSNFLVQAGIVKKEHIKIHGF
What is the function of this protein?
Probably involved in translation.
What are the official names of this protein?
Protein translation factor SUI1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SUI1 family.
Protein: RNZ_HALH5
Sequence: MEFHFFGTGSGVPSIERNVSACAVRFLQQRGKQWLFDCGEATQHQILRSSIALGKIERIFITHLHGDHIFGLPGLLGSRSFQGGENPLFLYGPKGIRSFVETALQVSNTHVKYELTIEEFSEPGLLFHEEGFKVETILLDHVMPCYAFKVTEDDRPGELLVDRLKAKGVPPGPLYRKIQQGETVELPTGERLEANAFLGPPKRGRSFVLAGDTRPVKELIPFAKNVNVLIHEATFLDDKKGHAHEYGHSTMADAIQLAKQANVDHLILTHISSRYHDMSDELQKKAQNAFANAVVAHDFYVFHLPLAKG
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: ARLY_MYCSJ
Sequence: MSTNEGSLWGGRFADGPADALAALSKSTHFDWVLAPYDIAASKAHARVLFSAGLLTEDQRDGLLAGLDSLASDVADGSFAPLVTDEDVHGALERGLIDRVGAELGGRLRAGRSRNDQVATLFRAWLRDAIRRVADGVLGVVSALATQAAAHPTAIMPGKTHLQSAQPVLLAHHLLAHAHPLLRDVERLADFDKRAAVSPYGAGALAGSSLGLDPDAIAAELGFDSAADNSIDATAARDFAAEAAFVLAMIGVDLSRLAEDIILWSTTEFGYVTLHDAWSTGSSIMPQKKNPDIAELARGKSGRLIGNLTGLLATLKAQPLAYNRDLQEDKEPVFDSVAQLELLLPAVAGLVSTLRFDVDRMAELAPLGYTLATDVAEWLVRRGVPFRVAHEAAGAAVRAAEARGVGLEDLEDAELTGIHPELTGDVREVLTVEGSVNSRDARGGTAPVQVAKQLNVVRDTADRLRLALRR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA1_BACCR
Sequence: MQCIETNNLQQLLEQVKPYTKKGKLATYIPELGNANPDDLGIAIFHKETEYIHAGNSQTLFTLQSISKVITLALALLDRGEEYVFSKVGMEPTGDPFNSIIKLETTSPSKPLNPMINAGALAITSMLEGKDNEEKMERILHFVREITDNPTINYSSKVADSELETAYLNRSLCYYMKQNGIIDCDIEELMDLYTRQCAVEVNCIDLARIGLIFAMDGYDPYKKKQIIPKHITKICKTFMVTCGMYNESGEFAIRVGIPAKSGVAGGIFGCVKGDMGIGIFGPALDANGNSIAGFKILELLSAQEGWSIF
What are the official names of this protein?
Glutaminase 1.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RL11_ECO81
Sequence: MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNAKTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RS13_BORPE
Sequence: MARIAGINIPPQQHAEIGLTAIFGIGRTRARKICEAAGVPVTKKVKDLTDAELERIREHIGVFAVEGDLRREVQLSIKRLIDLGTYRGMRHKRGLPVRGQRTRTNARTRKGPRRAAASLKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: TEKT3_BOVIN
Sequence: MELLGSTLTATYAHPRPTPTNFLPAISTMASTYRDRFPHYNLTHSLSLPWRPSTYYKAASNWPTLDPYCTRSQRVSESTMLPFVSNRTTLFTRYTPDDWYRSNLTNFQESNTSRHNSERLRVDTSRLIQDKYQQTRKTQADSTQNLGERVNDIGFWKSEIIHELDAMIGETNELTDIKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDEVEKELLTEVDTILCCQERMKLYLDKAIAQLAANRAAQHELEKDLSDKQSAYRIDDKCHHLRNTSDGVSYFHGVERVDATVSVPESWAKFTDDNILRSQSERAASAKLRDDIQNVLVVTANEMWNQFNKVNLAFTNRIAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIVEKSAFLKVAQTRLDERTRRPNIELCRDMAQLRLVNEVYEVDDTIQTLQQRLRDAEDTLQSLAHTKATLEHDLAVKANSLYIDQDKCMSMRRSFPSTLRLVGFC
What is the function of this protein?
Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme.  Forms filamentous polymers in the walls of ciliary and flagellar microtubules (PubMed:34715025).  Required for normal sperm mobility (By similarity).
What are the official names of this protein?
Tektin-3.
What is the protein family that this protein belongs to?
Belongs to the tektin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome outer membrane; Peripheral membrane protein. Note=In the sperm flagellum, localizes to the periaxonemal region where it associates with the mitochondrial sheath and outer dense fibers (By similarity). Not detected in the central axonemal region of the flagellum (By similarity). Associates with the acrosome membrane in the equatorial segment of the sperm head (PubMed:27883267). Also detected just below the plasma membrane in the post-acrosomal region where it might localize to the postacrosomal dense lamina (PubMed:27883267). However, other studies report little or no expression in the postacrosomal region (By similarity). Translocates from the postacrosomal region to the equatorial segment after sperm activation (PubMed:27883267). Retained in the postacromal region, but not the equatorial segment, following the acrosome reaction (PubMed:27883267). Some studies report strong expression in the anterior acrosomal cap region (PubMed:19478333, PubMed:26268136). However, other studies report little or no expression in the acrosomal cap (PubMed:27883267).
Protein: SYL_COXBR
Sequence: MNESYQPTLIEQLAQEYWEENETFEVKEDLSREKFYCLSMLPYPSGDLHMGHVRNYTIGDVIARYQIHKGRNVLQPMGWDAFGLPAENAAIQRELPPAEWTRKNIKKMRKQLKQLGFAYDWSREITTCDSTYYRWEQWLFLQLYKKGLAYKKNAIVNWDPVDQTVLANEQIVDGRGWRSGAVVERREISQWFLKITDYSEELLKDLDELKEWPEQVITMQRNWIGQSQGVIINFNFEKGPDKLQVYTTRPDTLMGVTYLAIAPEHPLAKERAKKSKKIAAFLKKCKQTRVAEADIATQEKEGIDSGLFAVHPLSKEKLPIWIANFVLMEYASGVVMAVPAHDERDHEFALKYDLPLKPVIEPADGHDWDYNQAAYTNPGKLINSGSFNDIDSKTAFNVIADYLKNNGAGSRQTHYRLRDWGISRQRYWGTPIPIIYCKTCGTVPVPENQLPVLLPEDIIPTGHGSPLKETASFYKTRCPVCNKPATRETDTMDTFVESSWYYARYSCPDQDKVMLDDRAKYWTPVDQYIGGIEHAVMHLLYARFMHKILRDLGLLNSNEPFIRLLTQGMVLKDGAKMSKSKGNVVTPQSLIKKYGADTVRLFIIFAAPPEQDLEWSDSGVEGAYRFLKKLWGFSYRIKDALLAINQQKERSNYQWEAPEHRQTRQQIHECLQQANIDMERLQFNTVVSAVMKILNILIKLTTDNDAEAHLIREGTGILLRLLSPITPHISHHLWQSLGFGGDILDTPWPRPDPKALQTTELELIVQINGKLRGRIQVPTEASKEIIESTALNQENVQRHLADKKIKKVIVVPKKLINIVV
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM7_CAEEL
Sequence: MGKTSRDKRDIYYRLAKENKWRARSAFKLMQIDDEFQILKGVRRAVDLCAAPGSWSQVLSKRLYEEDQEAKIVAIDLQPMAPIPGVIQLQGDITSVDTANQVIKHFSGEKSDIVICDGAPDVTGIHSLDEFMQAELILAAFNITSHVLKEGGNFLAKIFRSRNSSLLYAQMKKYFKKVYLAKPRSSRQSSCEAFVLCLDYSPPEGFVPTMGKTSLDATDASAISPDIIDGFVTCGDLSGWDSEKSYPLDIDACFPKGEIDEEQKKRYEFKDVVQPPTDPAYKAALDKKKSGVFAKMSADLNRQLKAELSRGKDQKKTPAENVPSVEELEKAAEKFQL
What is the function of this protein?
Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
What are the official names of this protein?
Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase, 2'-O-ribose RNA methyltransferase TRM7 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.