PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_SHEB2
Sequence: MVKKNSSKAAPATIARNKRATFEYRFEEKMEAGLSLMGWEVKSIRMGKVNLSDCYVFLKNGEAFMHGCTIIPLNTASTHVVCDPLRLKKLLLSRKELDKLAGLVERQGYSIIPISMYWRKGAWVKVEIGLGKGKKDHDKREDTKAREWEVEKARVMKKEKTHG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LG27_EUBMA
Sequence: VKRPMNAFMVWSQNERRKIMDQWPDMHNAEISKRLGRRWQLLQDSERYPLSRRRSVRLKHMADYPNYKYRP
What are the official names of this protein?
SRY-related protein LG27.
What are the subcellular locations of this protein?
Nucleus.
Protein: BOP1_RAT
Sequence: MAGACGKHHMSPGSLPGKRRLEPDQEPQIQEPLLLSDPDSSLSDSEESVFSGLEDSGSDTSDEDTEEVARAGCDKDNRTEKTSEEQEQAVPPCPRAEEAGALTRDEYEEDSSDEEDIRNTVGNVPLAWYDDFPHVGYDLDGKRIYKPLRTRDELDQFLDKMDDPDFWRTVQDKMTGSDLRLTDEQVALVHRLQRGQFGDSGFDPYEPAVDFFSGDIMIHPVTNRPADKRSFIPSLVEKEKVSRLVHAIKMGWIKPRRPPDSTPSFYDLWAQEDPNAVLGRHKMHVPAPKLALPGHAESYNPPPEYLPTEEERLAWMQQEPIERKLNFLPQKFPSLRTVPAYGRFIQERFERCLDLYLCPRQRKMRVNVDPEDLIPKLPRPRDLQPFPVCQALVYRGHSDLVRCLSVSPGGQWLASGSDDGTLRLWEVATARCMKTVRVGGVIRSIAWNPNPTICLVAAAMDDAVVLLNPALGDRLLVGSTDQLLETFTPPEEPTLQPAHWLEVSEEERQRGLRLRICHSKPVTQVTWHGRGDYLAVVLSSQGHTQVLIHQLSRRRSQSPFRRSHGQVQCVAFHPTRPFLLVASQRSIRIYHLLRQELTKKLMPNCKWVSSMAVHPAGDNIICGSYDSKLVWFDLDLSTKPYKVLRHHKKALRAVAFHPRYPLFASGSDDGSVIVCHGMVYNDLLQNPLLVPVKVLKGHSLTRDLGVLDVAFHPTQPWVFSSGADGTIRLFS
What is the function of this protein?
Component of the PeBoW complex, which is required for maturation of 28S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein BOP1, Block of proliferation 1 protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat BOP1/ERB1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: PYRC_ECO55
Sequence: MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILDAVPAGHNFTPLMTCYLTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIESVMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLVPFLAGETVRWSVKQ
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
Protein: PSBL_GNEGN
Sequence: MTQTNPNEQSVELNRTSLYWGLLLIFVLAVLFSNYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYFB_PSEU2
Sequence: MKFSEQWLRGWVSPQVSRDELVARLSMAGLEVDSVTLAAGVFSGVVVGEVLSTEQHPDADKLRVCQVSNGSETFQVVCGAPNVRPGLKIPFAMIGAELPGDFKIKKAKLRGVESNGMLCSAAELQAGEGNDGLMELAADAPVGQDIRVYLSLDDASIEVDLTPNRGDCLSVAGLAREVGALYAAEVTRPQVAAVSAVHDEVRPVEVLAPAACPRYLGRVIRNVDLSRPTPLWMVERLRRSDVRSIDAAVDITNYVMLELGQPLHAFDLAEINGGIRVRMAEEGEKLVLLDGQEVSLRADTLVIADHQRALAIAGVMGGEHSGVTAGTRDIFLESAFFDTISVAGKARSYGLHTDASHRYERGVDWQLAREAMERATGLLLEITGGEAGPVIEVVSEQHLPSIAPVTLRASRVEQMLGLVIENAEIERLLKGLGLAVTAEADGQWRVEVPSHRFDISLEVDLIEELARLYGYNRLPVRYPQARLAPQAKAEASGDLPELRRLLVARGYQEAITYSFIDPKWFELFSPGAKPLLLANPISNDMAAMRASLWPGLVKALQHNLNRQQDRVRMFESGLRFVGQLDGLKQEPMLAGVVCGSRLPEGWAQGRDAVDFFDVKADVEAVLGFAGALGEFTFTPGQHPALHPGQTARIERDGREVGFLGAIHPELSKTLGLDRPVFVFELVLAEVSTGRLPKFHELSRFPEVRRDLALLADRDVSASAVLDVIRENAGEWLTDLRLFDVYQGKGIDPHRKSLAVGLTWQHPSRTLNDDEVNATTLAILTSLEERLNATLRK
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PB2_I33A0
Sequence: MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRITEMIPERNEQGQTLWSKMNDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKIYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTTTKEKKEELQGCKISPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEARNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGIRMVNILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSVKREEEVLTGNLQTLKIRVHEGYEEFTMVGRRATAILRKATRRLIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKALFQNWGIESIDNVMGMIGILPDMTPSTEMSMRGVRISKMGVDEYSSAEKIVVSIDRFLRVRDQRGNVLLSPEEVSETQGTEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAVRGQYSGFVRTLFQQMRDVLGTFDTAQIIKLLPFAAAPPKQSGMQFSSLTINVRGSGMRILVRGNSPIFNYNKTTKRLTVLGKDAGPLTEDPDEGTAGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRNSSILTDSQTATKRIRMAIN
What is the function of this protein?
Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription.  Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA.  Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex.  In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS.
What are the official names of this protein?
Polymerase basic protein 2, RNA-directed RNA polymerase subunit P3.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB2 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Host mitochondrion.
Protein: NAT_NOCUT
Sequence: MTALSRVSGQAPDRVVETYAEGKPYDLFFLDVAGVRLVGRKTEAAYPGPDRDGLPAERLKCALVEARMLLGVVERDQVAEDHVAVFHRPLGEAEKAELFAAAVADPTTDLYYPYAQLGDRVRETEEGGWEVTDESARELDHAEEVLRDHVPDRLAELGFRGGVAYDAACSTGAFLQAVGRRFPGTRTIGQDLSPAMVARARTRLDEAHCGDGIRPAIPEASADLVVCRHLNAFVVGTGQAHDLLAAAASRCREGGLVVLLGHTPVLVSSQWCEMSGLTPLQRSGATPSGHALFQCYVLRKG
What is the function of this protein?
Involved in the biosynthesis of the beta-lactam antibiotic nocardicin A (PubMed:9804844).  In the presence of S-adenosyl-L-methionine (AdoMet), catalyzes the transfer of a 3-amino-3-carboxypropyl group from AdoMet to nocardicin G, forming isonocardicin C (PubMed:9804844).  Can also catalyze the transformation of nocardicin E and F to isonocardicin A and B, respectively, but in vivo substrate is probably nocardicin G (PubMed:9804844).
What are the official names of this protein?
Isonocardicin synthase, Nocardicin 3-amino-3-carboxypropyltransferase.
Protein: KHSE_STACT
Sequence: MSERLKLKVPASTANLGVGFDSIGLALNKFLYVEAEISDDQKWHFHHKGENLHDLPTDENHLIYQVVQFLEKRFEVTVPPLKITMRSEIPLARGLGSSASALVAGIYLADFFGQLQLSEFEMVEAATEIEGHPDNVAPVIYGGMVSGFYNNHTNETYISFIEPPRVNLVITVPSYELKTHDSRQVLPDSFKHGDAVQYSAISNTMLSALIQHDYVLAGKLMEMDGFHEPFRQKLIPEFEKVKSIAKEYKAYATVISGAGPTILTLIDPSKSGKLVRRLNKELDECSSEIIIINKSGIIAEKVYE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC_EUGGR
Sequence: GDAERGKKLFESRAAQCHSAQKGVNSTGPSLWGVYGRTSGSVPGYAYSNANKNAAIVWEEETLHKFLENPKKYVPGTKMAFAGIKAKKDRQDIIAYMKTLKD
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: CYSH_BACCZ
Sequence: MLTYETWEENNVSFSEEDETKGALSVLSWAYKEYEGEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPKLTLDEQAKLHGNKLWESNPNLCCKIRKILPLEESLANEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDIGYPSIGCEKCTLPVGEGGDSRDGRWAGKVKTECGLHYQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TXF09_LYCSI
Sequence: MNSKIFAVLFLLAFLSCVLSDQYCPKSSITACKKMNIRNDCCKDDDCTGGSWCCATPCGNFCKYPTDRPGGKRAAGGKSCKTGYVY
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
U15-lycotoxin-Ls1d, Toxin-like structure LSTX-N9.
What is the protein family that this protein belongs to?
Belongs to the venom protein 11 family. 01 (wap-1) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ODPA_CHATD
Sequence: MFSRAVRLSRAALPIRVASQRVPIAARRSVTTNAAQAQVDKSTIPESEDEPFTIRLSDESFETYELDPPPYTLEVTKKQLKQMYYDMVVVRQMEMAADRLYKEKKIRGFCHLSVGQEAVAVGVEHAIEKTDDVITSYRCHGFAYMRGGTVRSIIGELLGRREGIAYGKGGSMHMFTKGFYGGNGIVGAQVPVGAGLAFAQKYTGGKKATVILYGDGASNQGQVFEAFNMAKLWNLPALFGCENNKYGMGTSAARSSALTDYYKRGQYIPGLKVNGMDVLAVKAAVQYGKQWTVEGNGPLVLEYVTYRYGGHSMSDPGTTYRTREEIQRMRSTNDPIAGLKQRIINWGVATEEEVKGIDKAARAHVNEEVAAAEAMAPPEPTAKILFEDIYVKGTEPRYIRGRTLDEVYYFN
What is the function of this protein?
The 10-megadalton pyruvate dehydrogenase complex contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) and catalyzes the overall oxidative decarboxylation of pyruvate to form acetyl-CoA and CO(2) (PubMed:33567276, PubMed:34836937).  Within the complex, pyruvate and thiamine pyrophosphate (TPP or vitamin B1) are bound by pyruvate dehydrogenase E1 subunits alpha and beta and pyruvate is decarboxylated leading to the 2-carbon hydrohyethyl bound to TPP.  The E2 component contains covalently-bound lipoyl cofactors and transfers the hydroxyethyl group from TPP to an oxidized form of covalently bound lipoamide, and the resulting acetyl group is then transferred to free coenzyme A to form acetyl-CoA and reduced dihydrolipoamide-E2.  Finally, the flavoprotein dihydrolipoamide dehydrogenase (E3) re-oxidizes the lipoyl group of dihydrolipoamide-E2 to form lipoamide-E2 and NADH.  A fourth subunit, E3BP, is responsible for tethering E3 in proximity to the core, forming the entire metabolon (Probable).
What are the official names of this protein?
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial, Pyruvate dehydrogenase complex component E1 alpha, PDHE1-A.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: CDRTF_HUMAN
Sequence: MFSCCFPTSRGCCFRNGGSESLFRRCRRRLIPHPRRLSPVVIRRIQVPQDSLGQALAGQATPEIPLGLQLHTVLVQEIQELIEAQTLAPGPCAEVRALPAPAAEPEPAWEEAPPERALELEGAPAKDQTNEELPEITEVPESIKRRLGRRVPAATPAPRGNLLLQAWMRVHSWASRLFAPNVLPGTGP
What are the official names of this protein?
CMT1A duplicated region transcript 15 protein.
Protein: LEUC_RUTMC
Sequence: MTQTLYDKLMNAHVIRRDNSTELIYIDRQLIHEVTSPQAFEGLAIAGRKPWSTSANLAVPDHNVPTTNRSSGINGISDPISKLQIETLDKNCKTFGINEIPMNDIRQGIVHVVGPEQGFTLPGMSIVCGDSHTSTHGALGALAFGIGTSEVEHVLATGCLWQSKSKNFNIEVSGKLNKHVSAKDIALYIIGKIGTAGGTGHAIEFSGDTIQSLSIEGRMTLCNMAIEAGARVGMVAVDDKTIDYVKGRILAPSGAKWSKAVEYWHTLHSDKNAHFEKIAHFNAKDIKPQVTWGTSPEMVITIDGYIPNPANAKNHTEKVSWENALNYMQLTADIKISDIKIDKVFIGSCTNSRIEDLRIVASVLKDKKIANNIKLALVVPGSGLIKKQAEKEGLDKIFINSGFEWREAGCSMCLAMNADKLKVGERCISTSNRNFEGRQGQGSFTHLVSPAIAAASAITGHFSEVK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: PDHK2_CAEEL
Sequence: MRFSRKLLGPFVGSLAKKLDYYSQFQPSSLTIQQYLDFGRIGTSANSYTFLKNELLVRLANIMQEFTLLPPKLLQMPSSKMVSNWYAESFEDLLLFEASDSSPEQVARFNDQLTVVLKRHAHVVETMAEGLIELRESDGVDIASEKGIQYFLDRFYINRISIRMLQNQHLVVFGNVLPESPRHVGCIDPACDVESVVYDAFENARFLCDRYYLTSPSMKLEMHNAVEKGKPISIVAVPSHLYHMMFELFKNAMRATVEYHGVDDDLPDIKVYVVKGQEDLSIKICDRGGGVSRTILERLYNYMYSTAPPPPRDGTQAPLAGYGYGLPLSRLYARYFLGDLFLVSMEGHGTDACIYLKAVPVEASEVLPIYSTSSRRNLTMGPQVADWSHHVPGQGNRPAQS
What is the function of this protein?
Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism (By similarity).  Required for normal lifespan (PubMed:36173858).
What are the official names of this protein?
Probable [pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial, Pyruvate dehydrogenase kinase.
What is the protein family that this protein belongs to?
Belongs to the PDK/BCKDK protein kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: TRI59_MOUSE
Sequence: MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNFYIWRPLRIPLKCPNCRSIIEIASTGIESLPVNFALRAIIEKYQQEDHPDVVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLKQLTDTHWTDITRLIEKLEEQKCHSEKIVQGDKEVVLQYFKELIDTLEQKKKYFLAALCDVGKMINQEYTPQIQGMKEIREQQLELMTITTSLQDESPLKFLEKIDEVRQRVQMLKQRPLPEVQPVEIYPRVSNVLKEEWSRIEIGRIKKAVIPEMRVSSKRTPCSWSDNDEKEMELFKILNIAIVSLISVILMLILLFNHHIITFLNEITSICFSEVFLSVYQSLSKNLYDLNNTVCYTLYLLKEFMWKIVSR
What is the function of this protein?
E3 ubiquitin ligase involved in different processes such as development and immune response (PubMed:22588174, PubMed:29467473).  Serves as a negative regulator for innate immune signaling pathways by suppressing RLR-induced activation of IRF3/7 and NF-kappa-B via interaction with adapter ECSIT (PubMed:22588174).  Regulates autophagy through modulating both the transcription and the ubiquitination of BECN1.  On the one hand, regulates the transcription of BECN1 through negatively modulating the NF-kappa-B pathway.  On the other hand, regulates TRAF6-mediated 'Lys-63'-linked ubiquitination of BECN1, thus affecting the formation of the BECN1-PIK3C3 complex.  In addition, mediates 'Lys-48'-linked ubiquitination of TRAF6 and thereby promotes TRAF6 proteasomal degradation.  Acts also as a critical regulator for early embryo development from blastocyst stage to gastrula through modulating F-actin assembly and WASH1 'Lys-63'-linked ubiquitination (PubMed:29467473).
What are the official names of this protein?
Tripartite motif-containing protein 59, RING finger protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: MDH_ALIFM
Sequence: MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTPVSIKGYCGEDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVKSLTEKIAVTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDVIRSETFVAELKDKDPGEIRVPVIGGHSGVTILPLLSQVEGVEFTAEEVAALTPRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVKALSGEQGVVECAYVEGNGEHARFFAQPILLGKNGVEEIQSYGELSAFEQEALESMLDTLRGDIKIGEEFVQ
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
Protein: PUR7_CHLL3
Sequence: MKKTTLLHEGKAKKVFLTDEADLVIQEFKDDATAFNNKKKGTIAEKGVVNNAISCKLFTMLEGEGVRTHLVEKLSDRDMLCKKLDIIKVEVVVRNIAAGSLVKRYGFTEGSVLREPIVEFYLKNDDLDDPLMNESHAVALGVASLDELAVLGTRALRVNEVLKPFFAGVKLKLVDFKLEFGRHHGEILLGDEISPDTCRFWDLETNEKLDKDRFRLDLGGIEDAYSEVQKRVLGSGALS
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: MDTL_SHESA
Sequence: MFRYLLCCFGLVLMYPTGIDMYLVGLPQIANQLGATEAQLHIAFSVYLAGMATTMLFAGSLADRIGRKPITLFSALLFALASYFAARSQSSDLFLVARFVQGVGAGCCYVVAFAILRDALDDKRRAKVLSMVNGVTCIIPVIAPVIGHLIMLRFPWPSLFYTMAVMGLLVFGLCLFVLRETYSKASFHSQTLPRVQTESFKQGFFISRVVITTLGVTTILSYVNVSPMLIMGQMGFDRGQYSNTMAMTALVSMLASFSTPFLLNQFKEKSLILFSQTLFAAAALVFILTQLGWLGQLFNLLGFGLVCSGFAIGFGVTMSQALSPFVARAGVASSLLGIAQVCTSALYIWVMGLLEVSAINILLAILAVGALISITLMLAVPKLSEMVANEQIPESA
What are the official names of this protein?
Multidrug resistance protein MdtL.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtL (TC 2.A.1.2.22) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MDTD_YERE8
Sequence: MTGIRAQLWIVAFGFFMQTLDTTIVNTALPSMAASLGENPLRMQSVIVSYVLTVAVMLPASGWLADRVGVKWVFFSAIILFTLGSLLCAQAETLNELISSRVIQGIGGAMMVPVGRLTVMKIVPREQYMSAMAFVTLPGQIGPLVGPALGGFLVEYASWHWIFLINLPVGVVGALATLWLMPNYTTRTRRFDISGFIMLAIGMATLTLALDGHKGLGLPPLAIAGLILCGILALAGYWWHAKGNSSALFTLRLFNNKSYSLGLIGSMSARIGSGMLPFMTPVFLQIGLGFTPFHAGLMMIPMIIGSMGMKRIIVRVVNRFGYRRVLVSATLLLAVVSLSFPLVALMGWTLLLPIVLFFQGMLNALRFSTMNTLALKDLPNRLASSGNSLLSMVMQLSMSLGVSTAGILLGVFAHNQVVTNTPATHSAFLYSYICMAIIIALPALIFNRVPADTGTNRNLPRASAKAANR
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL21B_YEAST
Sequence: MGKSHGYRSRTRYMFQRDFRKHGAVHMSTYLKIYKVGDIVDIKANGSIQKGMPHKFYQGKTGVVYNVTKSSVGVIINKMVGNRYLEKRLNLRVEHIKHSKCRQEFLERVKANAAKRAEAKAQGVAVQLKRQPAQPRESRIVSTEGNVPQTLAPVPYETFI
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L21-B, Large ribosomal subunit protein eL21-B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL21 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAL3_YEAST
Sequence: MNTNVPIFSSPVRDLPRSFEQKHLAVVDAFFQTYHVKPDFIARSPGRVNLIGEHIDYCDFSVLPLAIDVDMLCAVKILDEKNPSITLTNADPKFAQRKFDLPLDGSYMAIDPSVSEWSNYFKCGLHVAHSYLKKIAPERFNNTPLVGAQIFCQSDIPTGGGLSSAFTCAAALATIRANMGKNFDISKKDLTRITAVAEHYVGVNNGGMDQATSVYGEEDHALYVEFRPKLKATPFKFPQLKNHEISFVIANTLVKSNKFETAPTNYNLRVIEVTVAANALATRYSVALPSHKDNSNSERGNLRDFMDAYYARYENQAQPWNGDIGTGIERLLKMLQLVEESFSRKKSGFTVHEASTALNCSREEFTRDYLTTFPVRFQVLKLYQRAKHVYSESLRVLKALKMMTSATFHTDEDFFTDFGRLMNESQASCDKLYECSCIETNQICSIALANGSFGSRLTGAGWGGCTIHLVPSGANGNVEQVRKALIEKFYNVRYPDLTDEELKDAIIVSKPALGTCLYEQ
What is the function of this protein?
The GAL3 regulatory function is required for rapid induction of the galactose system.  At normal induction, galactose in the presence of the GAL3 protein may lead to the induction of the GAL genes, including GAL1.  Then the galactokinase protein (GAL1) in the presence of galactose may reinforce the induction leading to a higher expression level.  Upon depletion of galactose, the inducing activity of the galactokinase protein may decrease, after which transcription of the GAL genes, including GAL1, may decrease.
What are the official names of this protein?
Protein GAL3.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
Protein: NSS_SBVBH
Sequence: MYHNGMQLHLTRRSGMWHLLVSMGNNSTSVLLESSSSTRRRPRWSYIRRHNQVSILLLVGSNLQWLITIFPNMSQILCQTMPLHFTGCQDI
What is the function of this protein?
Plays a role in the inhibition of the host immune response by intefering with the production of interferon in infected cells.
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the orthobunyavirus NS-S protein family.
Protein: IF5A_SULIN
Sequence: MSITYTTVGELKVGSYVVIDGEPCRVVEVTKAKTGKHGSAKANVVAIGVFSGAKKTLMAPVDQQVEVPIIEKHIGQIIADMGDKIQVMDLETYETFEIEKPTEDELASKIRPNAELEYWEIMGRRKIVRVK
What is the function of this protein?
Functions by promoting the formation of the first peptide bond.
What are the official names of this protein?
Translation initiation factor 5A, Hypusine-containing protein, eIF-5A.
What is the protein family that this protein belongs to?
Belongs to the eIF-5A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF27_ARATH
Sequence: MVHPRFVFFAFLALSVLLAVMNEDSILSSNKGDSLCCNDHPEFGICTNKSCNKWCLQGCTRGGFCKRKICHCYC
What are the official names of this protein?
Putative defensin-like protein 27.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.