PharMolix/UniProtQA huggingface dataset:
Protein: YBIX_ECO24
Sequence: MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCVTPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGENEEILSLLNLYHNLLREWSEI
What are the official names of this protein?
PKHD-type hydroxylase YbiX.
Protein: FOLD_MARN8
Sequence: MSAKLINGKEIAAQVRQQVAAGVEARKQKGLRAPGLAVVLVGHDPASQVYVGNKRKACEQAGILSLSYDLPEDTSQAALEALVDELNENPAVDGILVQLPLPSHLDADPILVKIRPDKDVDGFHPYNIGRLMQRKPTLRPCTPAGVITLLDSIGTPYKGQHAVIVGASNIVGRPMSMELLLKGATTTVCHRFTDNLEKFVGEADILVAAVGKPGIIKGEWVKPGATVIDVGINRMDDGKLCGDVDFDAAAERAAYITPVPGGVGPMTIATLLENTLYAANVLHADT
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: PA23_HELSU
Sequence: GAFIMPGTLWCGAGNAASDYSQLGTEKDTDMCCRDHDHCENWISALEYKHGMRNYYPSTISHCDCDNQFRSCLMKLKDGTADYVGQTYFNVLKIPCFELEEGEGCVDWNFWLECTESKIMPVAKLVSAAPYQAQAETQSGEGR
What is the function of this protein?
PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
What are the official names of this protein?
Phospholipase A2 isozymes PA3A/PA3B/PA5, PLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group III subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CHBF_ECOLI
Sequence: MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGGKPKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERIPLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVYRHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLINGKSRFAELLDGVASGQLKASSVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEYYKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQAEHYVNIPHHGQIDNIPADWAVEMTCKLGRDGATPHPRITHFDDKVMGLIHTIKGFEIAASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
What is the function of this protein?
Hydrolyzes a wide variety of P-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, gentiobiose-6P, methyl-beta-glucoside-6P and p-nitrophenyl-beta-D-glucopyranoside-6P.  Is also able to hydrolyze phospho-N,N'-diacetylchitobiose.
What are the official names of this protein?
6-phospho-beta-glucosidase, Cellobiose-6-phosphate hydrolase, Phospho-chitobiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 4 family.
Protein: ZDH11_MOUSE
Sequence: MKEMNICGINKNWVLPEAQENNVKKFLPRPLSRVNGWSPPLHSFQAISWITYLAMSIVTFGIFIPFLPYSWKYAANIVMGGVFIFHLIVHLIAITIDPADTNVRLKKDYTQPVPAFDRSKHTHVIQNQYCHLCEVTASKKAKHCSACNKCVSGFDHHCKWLNNCVGRRNYWFFFWSVASAAVGILGVMIILCYICIQYFVNPDELRTDPLYKEIISENTWLLFLSLWPVPVKTPIVLSIAVMALLLAIASFVMLGHLLIFHLYLITKNMSTFDYLMKTRFKKNLHPAEEKELPLQKKGDLPQEKSDNWAWPKSPPRVGSQKFPVSTLSPKSSVCFVASPPKICHSED
What is the function of this protein?
Has also a palmitoyltransferase activity-independent function in DNA virus-triggered and CGAS-mediated innate immune response (PubMed:29429998).  Functions as an adapter that recruits IRF3 to STING1 to promote the activation of that key transcriptional regulator of type I interferon (IFN)-dependent immune response (PubMed:29429998).
What are the official names of this protein?
Palmitoyltransferase ZDHHC11, DHHC-containing protein 10, DHHC10(z11), Zinc finger DHHC domain-containing protein 11, DHHC-11.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endosome membrane; Multi-pass membrane protein.
Protein: CTNR_MONRU
Sequence: MASTAHRQPSRPTTRQRQRTGRACEECRRRKLRCDGQQPRCGVCVDSGVTCEVNSQRRPRGPKKGYLTALRNRVAMLETRLPAQHLVGPLSEFNPLSTPLTNDHHDGCSVSSASSRSDSNPPPTVSEPDMSLPNTTTSVSSAPSFATCSKDIGGAEPITELVQAELNQLYFDRVHPSIQILHQRRYLGWARNAAKKTSRRCLQYAVWTLASLLSAQFQHLQDSFYQETKRTLEFSYLSGDSNAPVDTEEIQAWILIATYESMRTFHRSAWMSAGRAFRLVQLMRLHEIDSPTKPPVPEADLVETEEKRRVFWMAYFLDHLLSMRNNWPITLNEHVICTRLPAPDMEFQSGQPVLGAFLSEAIMDVMPQTTSPFNECVILATICGRSLFHAQQYSVRFVYGELAPNWTDQHQWLDNVLTNRLQILSQYYPSPTQICDPMLSFAHIMGQASVIHLYKGMASVVWAVDDGAWVVEYQRRALSAAQEIVKLAKGLTEFNFFKVCHTASLPCND
What is the function of this protein?
Transcription factor that regulates the expression of the gene cluster that mediates the biosynthesis of the mycotoxin citrinin, a hepato-nephrotoxic compound to humans due to inhibition of respiration complex III (Ref. 1).
What are the official names of this protein?
Citrinin biosynthesis transcriptional activator mrl3.
What are the subcellular locations of this protein?
Nucleus.
Protein: HPDL_CLODR
Sequence: MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLLDVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQKTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNVVSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFDSGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVIQVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLTYTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCIDCFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLYDEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCLETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDHRMNIQVFEPHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKGQHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKDALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEEAQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYALFESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSETLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV
What is the function of this protein?
Glycyl radical subunit of the HPA decarboxylase that decarboxylates phenylacetates with a hydroxyl group in the p-position.  Active toward 4-hydroxyphenylacetate and 3,4-dihydroxyphenylacetate, forming 4-methylphenol and 4-methylcatechol, respectively.  Is likely involved in the catabolism of aromatic amino acids such as tyrosine fermentation.  4-methylphenol (p-cresol) formation provides metabolic toxicity, which allows an active suppression of other microbes and may provide growth advantages for the producers in highly competitive environments.  The large subunit is the catalytic subunit that binds the substrate.
What are the official names of this protein?
4-hydroxyphenylacetate decarboxylase glycyl radical subunit, HPA decarboxylase glycyl radical subunit, 4-hydroxyphenylacetate decarboxylase catalytic beta subunit, 4-hydroxyphenylacetate decarboxylase large subunit, p-hydroxyphenylacetate decarboxylase large subunit.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family. HPAD subfamily.
Protein: RSBW_STAAE
Sequence: MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
What is the function of this protein?
Negative regulator of sigma-B activity.  Phosphorylates and inactivates its specific antagonist protein, RsbV.  Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B).
What are the official names of this protein?
Serine-protein kinase RsbW, Anti-sigma-B factor, Sigma-B negative effector RsbW.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: ATPG_CHLT3
Sequence: MATLREIRTRIKSVKSTQQLTKAMKMVAAAKLRRAQDRALQARPYAAKLKELLDSLSGKVDTTINPLLTPRSEVKNVLVILVTSDRGLCGAFNTNIIKMAQRLIDQDYADMSRQGRVKMICAGRRGNDFFRKRGYNVVYGYPNIFNQLDFNAAKEIVEKATELYLSGEVDKVHVIYNEFKNVVSPNLISEVFLPIAPSKKDDAGSDAARQNKLVPIVDYIYEPSPEAIINELVPKHLNTQLWRVLLESNAAEQASRMTAMDSATDNAKELLRSLSITYNRARQAAITKEILEIVGGANALEQSA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: YCQ4_SCHPO
Sequence: MAIPILDALTSSSGKKNSAEFSIHSTSNPTNPEEPNITSEADNAEDLAALGYKQEFQRGLSLFSVFSVSFSLLGLLPSVATTLPYSIGYTGTPGLLWGWLIAMVFIICIALSMAELCSAMPTSGGLYYAAAVLAPEGWGPLAAWFTGWSNYIAQLVGGPSINYSTAAMLLGAVNIGNPNYEVQNYQLFLVSIAIQFIHFILASMPTKYIAKLNSVGTYLNTLFLFISMIVILAMSSKNHGFNETSKVWSHIENYTDWPDGFAILMSFCGVIWTMSGYDAPFHMSEETANASVNAPRGIILTAAIGGIMGWVMQIVIAYTVVDQTAVVTGSDSMWATYLSQCLPKRAALGILSLTIVSSFLMGQSNLIASSRIAYSYARDGVLPYSEWVATVNPITKTPIRAVFVNFVIGVLILFLAFAGAITIGAVFSVTAIAAFTAFVAPVAMRVFFVKDADFRTGPFNLGKFSKPIGFCSVSFVALMIPILCFPSVKNPTPAEMNWTCLVFGAPMLAVLIWYAISGRKWFKGPRINLASEGDNSTLEGVELYTGSEELPQKKEKE
What are the official names of this protein?
Uncharacterized amino-acid permease C74.04.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RPAB1_DEBHA
Sequence: MEDTDRTISRLWRSFKTVKEMVRDRGYYITQEEIDMSLAEFRSRICDSMNVPQRKLMCFQANPTAESLEKFPDLGSLWVEFCDEASVGIKTMRNFCIHISEKNFSTGIFIYQSSITPSANKLIPTVSPASIETFQEGDLVVNITHHDLVPKHIKLARDEKKELLERYRLKESQLPRIQREDPVGRYLGLKRGEVVKIIRRSETSGRYASYRICL
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  Pols are composed of mobile elements that move relative to each other.  In Pol II, RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template.  Seems to be the major component in this process (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerases I, II, and III subunit RPABC1, RNA polymerases I, II, and III subunit ABC1.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS19_PARD8
Sequence: MSRSLKKGPYINVKLEKKVLAMNESGKKAVVKTWARASMISPDFVGHTIAVHNGNKFIPVFVTENMVGHKLGEFSPTRTFRGHAGNKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RPOA_PSEAE
Sequence: MQSSVNEFLTPRHIDVQVVSQTRAKITLEPLERGFGHTLGNALRRILLSSMPGCAVVEAEIDGVLHEYSAIEGVQEDVIEILLNLKGLAIKLHGRDEVTLTLAKKGSGVVTAADIQLDHDVEIINGDHVIANLADNGALNMKLKVARGRGYEPADARQSDEDESRSIGRLQLDASFSPVRRVSYVVENARVEQRTNLDKLVLDLETNGTLDPEEAIRRAATILQQQLAAFVDLKGDSEPVVEEQEDEIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLDNWPPASLKKDDKATA
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ACTS_HUMAN
Sequence: MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, alpha skeletal muscle, Alpha-actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: ACEA_CANTR
Sequence: MAYTKIDINQEEADFQKEVAEIKKWWSEPRWRKTKRIYSAEDIAKKRGTLKIAYPSSQQSDKLFKLLEKHDAEKSVSFTFGALDPIHVAQMAKYLDSIYVSGWQCSSTASTSNEPSPDLADYPMDTVPNKVEHLWFAQLFHDRKQREERLNMTKEERANTPYIDFLRPIIADADTGHGGITAIIKLTKLFIERGAAGIHIEDQAPGTKKCGHMAGKVLVPVQEHINRLVAIRASADIFGSNLLAVARTDSEAATLITSTIDHRDHYFIIGATNPESGDLAALMAEAEAKGIYGDELARIETEWTKKAGLKLFHEAVIDEIKAGNYSNKEALIKKFTDKVNPLSHTSHKEAKKLAKELTGKDIYFNWDVARAREGYYRYQGGTQCAVMRGRAFAPYADLIWMESALPDYNQAKEFADGVKAAVPDQWLAYNLSPSFNWNKAMPADEQETYIKRLGQLGYVWQFITLAGLHTTALAVDDFANQYSQIGMRAYGQTVQQPEIEKGVEVVKHQKWSGANYIDGLLRMVSGGVTSTAAMGAGVTEDQFKETKAKV
What is the function of this protein?
Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle.  Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available.  Acts also on 2-methylisocitrate.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase, Methylisocitrate lyase, MICA, Threo-D(S)-isocitrate glyoxylate-lyase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
What are the subcellular locations of this protein?
Glyoxysome.
Protein: MCES_ENCCU
Sequence: MEGKKEEIREHYNSIRERGRESRQRSKTINIRNANNFIKACLIRLYTKRGDSVLDLGCGKGGDLLKYERAGIGEYYGVDIAEVSINDARVRARNMKRRFKVFFRAQDSYGRHMDLGKEFDVISSQFSFHYAFSTSESLDIAQRNIARHLRPGGYFIMTVPSRDVILERYKQGRMSNDFYKIELEKMEDVPMESVREYRFTLLDSVNNCIEYFVDFTRMVDGFKRLGLSLVERKGFIDFYEDEGRRNPELSKKMGLGCLTREESEVVGIYEVVVFRKLVPESDA
What is the function of this protein?
mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs.  Binds RNA containing 5'-terminal GpppC.
What are the official names of this protein?
mRNA cap guanine-N7 methyltransferase, mRNA (guanine-N(7))-methyltransferase, mRNA cap methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KPTA_PSEAB
Sequence: MDRKTLDDTSKFLSYVLRHQPEAIGLKLDGEGWADIDALIAGAARDGRALDRALLGAVVENNDKKRFALSADGQRIRAVQGHSHAAVAIAYAPAVPPAVLYHGTASRFLDSIRERGLVPGSRHHVHLSARRATALEVGRRYGSPVLLEIDARDMHLAGHLFHQAENGVWLTERVPVRFIREA
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase.
What are the official names of this protein?
Probable RNA 2'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: PYRH_PYRNV
Sequence: MAVVVKLSGRIFEDEELVLKYAEAIKSYGVKIAVVTGGGELARRYISAAKRGGASNTFQDLIGIYASRLNALLLISLLGDAYPKVPTNIEEFLEAWRSHRVVVAGGFQPGQSTATVAALVAEAAGASVLLNAANIDAVYSDDPRKNPKAERLPHLKYDEFERIVRSSSLPGGYELMDVWSISILRRNCITVYIFDGRRPEHIGAILRGENPGTKITC
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BUCAI
Sequence: MLNPIVRKFQYGQHTITLETGVIARQANAAVMASMDETAVFVTVVGQKKIHTGQKFFPLTVNYQERTYAAGRIPGGFFRREGRPSENEILTARLIDRPLRPLFPKKFLNEIQIIATVVSVNPQINPDIISIIGASAALSLSGIPFYGPVGAARVGYINNQYILNPISDDMKNSSLDLVVSGTQNAILMVEAESKILSEEKILGAIIFGHQQQQVVINNIRSLSNEASKLPWVISYPETNKTLELKIINSFEKNISDAYVIFNKQDRIEKLNSIKENIIKLFLDENSNIDTLEIEDIFQKIEKKVVRKRILSNQTRIDGREKDMIRALDVRTGILPRTHGSALFTRGETQSLVSVTLGTSRDAQNLDELLGDRIDNFLFHYNFPPYSVGEIGMVGSPKRREIGHGRLAKRSLLAVMPTLENFPYTIRVVSEITESNGSSSMASVCGASLALMDAGVPIKSAVAGISMGLVKEGNQHVLLSDILGDEDHLGDMDFKVAGTEEGITALQMDMKIEGITNEIIHSALNEARLARLHILNVMNQALNESRSEISEFAPRIHIIKINPEKIKDVIGKGGSVIRMLTEETGTIIEIEDDGTVKISSTVKEKAKNAIRRIKEITAEIEVGRIYSGKVTRIVDFGAFVSIGLGKEGLVHISQISDKRVDKVSNHLKIDQIISVKVLEIDRQGRLRLSIKEIDSSILSNKSINNSII
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_LACDA
Sequence: MLQPIGDRVIVEVKEVEEQTVGGIVLASNAKEKPTQGKVVAVGGGLYAEDGSKLPMTVQEGDEVLYDKYSGTKVKYEDKEYLVLHEKDILAIVK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFA_PSEA7
Sequence: MENLDALVSQALEAVRHTEDVNALEQIRVHYLGKKGELTQVMKTLGDLPAEERPKVGALINVAKEKVQDALNVRKTELEGAALAARLAAERIDVTLPGRGQPSGGLHPVTRTLERIEQCFSRIGYEVAEGPEVEDDYHNFEALNIPGHHPARAMHDTFYFNANMLLRTHTSPVQVRTMESQQPPIRIVCPGRVYRCDSDLTHSPMFHQVEGLLVDEGVSFADLKGTIEEFLRAFFEKQLEVRFRPSFFPFTEPSAEVDIQCVICSGNGCRVCKQTGWLEVMGCGMVHPNVLRMSNIDPEKFQGFAFGMGAERLAMLRYGVNDLRLFFDNDLRFLGQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_CALBD
Sequence: MYEEMDSLIEKASILIEALPYIQKLYGKTVVIKYGGNAMINEKLKNWVMEDITLLKYIGVNPIVVHGGGPDINSVLKKLNVESQFVNGLRVTDMQTMEVAQMVLVGKTNKELVSMLNQKGGKAIGICGIDGNLIQARKHYEYVNGEKIDLGYVGEVVSINAKVLEMLAKDEYIPVVAPIGVGEDGTSYNINADTVAAEIAKAIKAEKLMFMTDVEGLKYDKNSKKIISAISADEVLKMIEEGKIDGGMIPKVLGCIDALKHGVNRTHILDGRIPHCILLEIFTDKGIGTMIHL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TILS_CHLPN
Sequence: MVLSSDLLRDDKQLDLFFASLDVKKRYLLALSGGSDSLFLFYLLKERGVSFTAVHIDHGWRSTSAQEAKELEELCAREGVPFVLYTLTAEEQGDKDLENQARKKRYAFLYESYRQLDAGGIFLAHHANDQAETVLKRLLESAHLTNLKAMAERSYVEDVLLLRPLLHIPKSSLKEALDARGISYLQDPSNEDERYLRARMRKKLFPWLEEVFGKNITFPLLTLGEESAELSEYLEKQAQPFFSAATHQDSQGELPCPDCLIQQAFLCKWVMKKFFNNAGIAVSRHFLQMVYDHLSRSSCATLRMRNKIVIIKPGVVVID
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIB_SALPA
Sequence: MTILAWCIAWVLDFIIGDPQHWPHPVRWIGRLITFVQRIVRRYCPGDKALRIGGGVMWVVVVGVTWGVAWGVLALAQRIHPWFGWSVEVWMIFTTLAGRSLARAAQEFERPLRENDLAESRIKLSWIVGRDTSQLQPAQINRAVVETVAENTVDGIIAPLFFLFLGGAPLAMAYKAVNTLDSMVGYKHEKYRAIGMVSARMDDVANYLPARLSWLLLGIAAGLCRLSDWRALRIGWRDRYNHSSPNCAWSEACVAGALGIQLGGPNNYFGERVDKPWIGDAQRGISVDDISRTIRLMWVASTLALALFIAARCGLSGVA
What is the function of this protein?
Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.  However, the true cosubstrate could be (R)-1-amino-2-propanol O-2-phosphate, leading to cobinamide phosphate.
What are the official names of this protein?
Cobalamin biosynthesis protein CbiB.
What is the protein family that this protein belongs to?
Belongs to the CobD/CbiB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CRBN_DROYA
Sequence: MDDEETSEINSVQGQDEDVQLEVQPQAQGPQDRQVDAIEQAWNNATQDEQSPPAEEAFQDPLAIDGEGGNAPEAMVEDVLQDDTASEGSHPSSDMSLETPGSEDDSDLELLPRWMIPQNRLRSAVDMMVSQARNRDGGIAALLNRDNFLQRVRSIVFSQERRRSRTSEETSQEAADAEQPNDPPPQQPPRPPIDIGFDTNLPAEHSYFGNHLSRVPGVDYLEVGSVHHMLIFLHQHILFPGEVLPFMIDGRMFDEDMPGLDGLIFGVGFPLMQPPEDNPLKLYGVTCQIYERGESGRGLVFYKSRALQRIVINCEDIQGSPQYIARNPTSKCFSKVKILPEYFLPEPLQSVEMGSMARFRDIPSMRDKYRRFQLSTTTWPSDACQEYSFASIVERARQRLESQKIDTMPKCPIQLSFWLVRNLHLTEKMMRLTFLTDSVNTRLQLIKSTFKDESLFFCRYCNSSLAHCADLFAMSKHGVQTQYCNPDGYIHETNTVYRVMSHAIGYSGEPSTKFSWFPGYQWHIILCKFCAQHVGWEFKAVQPNLTPRVFFGLAGSSVRIGKASENTPFNGSTYVVRNMLRLISNEME
What is the function of this protein?
Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins.  Has an essential role in mediating growth by negatively regulating insulin signaling.  It also has a role in maintaining presynaptic function in the neuromuscular junction synapses of third-instar larvae.
What are the official names of this protein?
Protein cereblon, Protein ohgata.
What is the protein family that this protein belongs to?
Belongs to the CRBN family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL30_FRACC
Sequence: MAKLRITQIRSGIGGTSNQRATLRTLGLRKINATTVRDDRPEIRGMIRTVTHLVRVEEVDS
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: YOZY_BACSU
Sequence: MNLRKILLSSALSLGMLVSAAPVLATSSSSEVIVKSDEYDYDTIYQLSPLPNFKPSIEYNGYTYTLTRYYFDYSIQFYTAIYTKVV
What are the official names of this protein?
Uncharacterized protein YozY.
Protein: RUVC_FRATF
Sequence: MVILGIDPGSRITGFGVIKVQDNKIYYVASGCIQITEITTPKRLKQIADGITQIINIYAPTEAAIEQIFMFQNPMGAIKLGQARGVAMCTLAINNLEVSEYSAKQIKQAVVGTGGAAKSQVQHMVQSLLGLSKKPPEDAADALAIAICHYHSSKSLAKISGASRVSQKRIK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.