PharMolix/UniProtQA huggingface dataset:
Protein: AOC1_HUMAN
Sequence: MPALGWAVAAILMLQTAMAEPSPGTLPRKAGVFSDLSNQELKAVHSFLWSKKELRLQPSSTTTMAKNTVFLIEMLLPKKYHVLRFLDKGERHPVREARAVIFFGDQEHPNVTEFAVGPLPGPCYMRALSPRPGYQSSWASRPISTAEYALLYHTLQEATKPLHQFFLNTTGFSFQDCHDRCLAFTDVAPRGVASGQRRSWLIIQRYVEGYFLHPTGLELLVDHGSTDAGHWAVEQVWYNGKFYGSPEELARKYADGEVDVVVLEDPLPGGKGHDSTEEPPLFSSHKPRGDFPSPIHVSGPRLVQPHGPRFRLEGNAVLYGGWSFAFRLRSSSGLQVLNVHFGGERIAYEVSVQEAVALYGGHTPAGMQTKYLDVGWGLGSVTHELAPGIDCPETATFLDTFHYYDADDPVHYPRALCLFEMPTGVPLRRHFNSNFKGGFNFYAGLKGQVLVLRTTSTVYNYDYIWDFIFYPNGVMEAKMHATGYVHATFYTPEGLRHGTRLHTHLIGNIHTHLVHYRVDLDVAGTKNSFQTLQMKLENITNPWSPRHRVVQPTLEQTQYSWERQAAFRFKRKLPKYLLFTSPQENPWGHKRTYRLQIHSMADQVLPPGWQEEQAITWARYPLAVTKYRESELCSSSIYHQNDPWHPPVVFEQFLHNNENIENEDLVAWVTVGFLHIPHSEDIPNTATPGNSVGFLLRPFNFFPEDPSLASRDTVIVWPRDNGPNYVQRWIPEDRDCSMPPPFSYNGTYRPV
What is the function of this protein?
Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis.  Placental DAO is thought to play a role in the regulation of the female reproductive function.
What are the official names of this protein?
Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RL29_TRIV2
Sequence: MPLPKISEARELSDERLVEEITAVKKQLFQLRLQKATRQLDKPHQFRHARHRLAQLLTVEGERKRAAATQSPQE
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: ADA2A_BOVIN
Sequence: MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISFEKKRGRSGQPSAEPRCEINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDATAAELPGSAERRPNGLGPERGGVGPVGAEVESLQVQLNGAPGEPAPAGPPDADALDLEESSSSEHAERPPGSRRSERGPRAKGKARASQVKPGDSLPRRGPGATGLGAPTAGPAEERSGGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAIGCPVPPTLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
What is the function of this protein?
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.  Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (By similarity).
What are the official names of this protein?
Alpha-2A adrenergic receptor, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR, Alpha-2D adrenergic receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLSB_PSEE4
Sequence: MTRSPLRRLIFGALRRVLYLWVRSETINQSSLTLKLDRSRPVFYALSSPSLTDLAVVDHECTKAGLPRPVLPVAVGPLQEPAGFFYLTPDPDWLGRQDKRGAPPTLERLVAAISQHAEEDTQIIPVSVFWGQTPASESSPWKLLFADSWAVTGRLRRLLSVLILGRKTRVQFSAPIHLRELVDHNKGHERTVRMAQRVMRVHFRNLKTAVIGPDISHRRNLVKGLVHDPLVRQAISDEAEREKIPYAKAEAKALHYGNEIASDYTYTAIRFLEVVLSWFWNKIYDGVKVNHIEQVQGIAPGHEVIYVPCHRSHIDYLLLSYLLFRNGLTPPHIAAGINLNMPVIGGLLRRGGAFFMRRTFKGNPLYTAVFNEYLHTLFTKGFPVEYFVEGGRSRTGRMLQPRTGMLAITLRSFLRSSRTPIVFVPVYIGYERVLEGRTYLGELRGASKKKESIFDIFKVIGALKQRFGQVYVNFGEPIRLAGFLDEQQPGWREQELGPQFRPTWLNETTTRLGETVARHLNEAAAINPVNLVALALLSTSRLALDERALTRVLDLYLALLRQVPYSPHTTLPEGDGQALIKHVLGMDLLAEQKDAMGRILYLDEANAVLMTYYRNNVLHIFALPGLLASFFLSSSRMSRDLLGQYVRALYPYLQAELFLRWTPEQLDEVIDQWLAALVSQGLLRQENDIYMRPAPSSRQFVLLTLLARTITQTLQRFYMATSLLLNSGQHTLSAEELEELCVMMAQRLSILHGLNAPEFFDKTLFRHFIQTLVREGVLQPDGDGKLGYHDKLAELAEGVAKRVLSAELRLSIRQVALHRDEPQENPET
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NUOB_AFIC5
Sequence: MGLNPTQVSTSGSPQVSQPATGVLDPRTGQPVGADDRYFLEINHELSDKGFFVAAADDLITWARTGSLMWMTFGLACCAVEMMQVSMPRYDVERFGFAPRASPRQSDVMIVAGTLTNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGVLLLQKKIRRIGTIER
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MEP4_TRITO
Sequence: MHGLLLAGLLALPLNVLAHPTESHSSGISRRAIDITSYRLPQISKYTKSDAVPKQDDESFTTSSTGDDNVSSGDYVTTATDWLKKTLPKATYRLVNDHYIGDSGIGHVHFRQTAHGIDIDNTDFNVNIGRDGKVFSFGNSFYDGEIPKANPMVKRDFSDPVNALQVAIQTLNLPVTAKPENVKAKPVEGKENFKFEGTSGAFSDPKAQLVYLQKDGGLVPSWKVETDIGDNWLLTYVDANKNDKVHSVVDYVSAAEYKVYPWGINDPTEGNRTSIHLPWFKTLSTDWHIDGKGWYSTTRGNNAIAQENPTGGPEYENNYRPKSPLFIFKYPYSEAMTPPSSYRDASITQLFYTTNVYHDVLYILGFNEKAGNFQVNNWNKGGVGGDFAILNSQDGSGVNNANFATPPDGQPGRMRMYTWNASTPERDGCFEAGIVIHEYTHGVSNRLTGGPANSRCLAALESGGMGEGWSDFFATAIRLKAGDTRATDYTMGEWASNRPNGIRKYRYSTNLTTNPHMYVDADGLTSVHAIGTIWASMLYELLWNLIDKHGKGDVTKVRPVLKNGVPTDGRHLAMKLVLDGMALQPCLPNFVQARDAILDADKVLTQGSNKCEIWKAFAKRGLGVGAVFNPSKRTGSNELPAGC
What is the function of this protein?
Secreted metalloproteinase probably acting as a virulence factor.
What are the official names of this protein?
Extracellular metalloproteinase 4, Fungalysin MEP4.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NIFD_CLOPA
Sequence: MSENLKDEILEKYIPKTKKTRSGHIVIKTEETPNPEIVANTRTVPGIITARGCAYAGCKGVVMGPIKDMVHITHGPIGCSFYTWGGRRFKSKPENGTGLNFNEYVFSTDMQESDIVFGGVNKLKDAIHEAYEMFHPAAIGVYATCPVGLIGDDILAVAATASKEIGIPVHAFSCEGYKGVSQSAGHHIANNTVMTDIIGKGNKEQKKYSINVLGEYNIGGDAWEMDRVLEKIGYHVNATLTGDATYEKVQNADKADLNLVQCHRSINYIAEMMETKYGIPWIKCNFIGVDGIVETLRDMAKCFDDPELTKRTEEVIAEEIAAIQDDLDYFKEKLQGKTACLYVGGSRSHTYMNMLKSFGVDSLVAGFEFAHRDDYEGREVIPTIKIDADSKNIPEITVTPDEQKYRVVIPEDKVEELKKAGVPLSSYGGMMKEMHDGTILIDDMNHHDMEVVLEKLKPDMFFAGIKEKFVIQKGGVLSKQLHSYDYNGPYAGFRGVVNFGHELVNGIYTPAWKMITPPWKKASSESKVVVGGEA
What is the function of this protein?
This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation.
What are the official names of this protein?
Nitrogenase molybdenum-iron protein alpha chain, Dinitrogenase, Nitrogenase component I.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: Y840_HAEIN
Sequence: MAQHSKYSDAQLSAIVNDMIAVLEKHKAPVDLSLIALGNMASNLLTTSVPQTQCEALAQAFSNSLINAVKTR
What are the official names of this protein?
UPF0352 protein HI_0840.
What is the protein family that this protein belongs to?
Belongs to the UPF0352 family.
Protein: ILVC_DEIGD
Sequence: MAATMYYDRDVSLSPIEDKLIAIIGYGSQAHAHAQNLRDSGLNVVVGLREGSPSRPKAEQAGLRVTSIEDATREADVIMLLIPDETQPKVYEESIAPNLTAGKALAFGHGFNIHFGRIKPPADVDVFLVAPKGPGHMLRRVYVDGAGMPSIFAVGQDASGNARDLALAYARGIGGTRAGVLETTFKEETETDLFGEQSVLCGGVTHLIQAGFETLVEAGYQPEIAYFETLHEVKLIVDLIYEKGFEGMRHSISNTAEYGDYVTGPRIITDETKATMKDVLSDIQSGKFARDFIHEAESGFPFMKEQRQKMRHHTLEVVGRELRSKMPFISKQELEV
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LIGB_SALA4
Sequence: MRLWKSMAWGILLWHSQSGALCPAWPPARAAEEIARLQQQLADWNDIYWKQGVSAVDDSVYDQLSARLVQWQRCVGQDVSSTPVSPPLNGTTMHPVAHTGVRKLADRQAVEQWMRGRSELWVQPKVDGVAVTLVYQNGKLTRAISRGNGLQGEDWTPKIRLIPSIPQTTQGALANAVLQGEIFLQREGHIQQRMGGMNARSKVAGMLMRQDNASALNSLGIFIWAWPDGPANMPERLSQLAKAGFSLTKKYSLVVKDASEVERARQSWLTSALPFVTDGVVIRMAKEPASQYWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKITVVASLVPVILDDKRVQRVNIGSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPDSHFNSLTCFYASATCQEQFISRLVWLGSRSALGLDGMGEASWRALHQTHRFEHIFSWLTLTSAQIANTPGFAKGKSEQIWRQFNLARRQSFTRWIMAMDIPLTQAALQASGDRSWEQLLMRTEQHWRQLPATGERRAGRVIDWRNNPQIKTLSRWLAAQHIPGFGS
What is the function of this protein?
Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.
What are the official names of this protein?
DNA ligase B, Polydeoxyribonucleotide synthase [NAD(+)] B.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigB subfamily.
Protein: PLB_DRYCN
Sequence: MVRFGSAASSDNRRRRCWSWYWGGLLLLWAVAETRADLHYATVYWLEAEKSFQVKDLLDKNGDAYGYYNDTVQSTGWGILEIKAGYGSQLVSNEILMYAAGFLEGYLTASRMSDHVANLYHQMIKNVITEQKVKDFMQKQDEWTRQQIKNNKDDPFWRNAGYIIAQLDGLYMGNLEWAKRQKRTPLTKFEISFLNALGDLLDLIPALSPESRNNGFLSMSEISKMYEWDMGHCSALIKVLPGYENIYFAHSSWFTYAATLRIYKHLDFRIIDPQTKTGRASFSSYPGLLASLDDFYILGSGLIMLQTTNSVFNISLLQQVVPESLFAWERVRIANMMADSGKTWAQTFKKQNSGTYNNQYMILDTKKIKLRRSIEDGTLYIIEQVPNLVEYSDQTTILRKGYWPSYNIPFHKVIYNMSGYREYVQKYGLDFSYEMAPRAKIFRRDQGKVIDIESMKRIMRYNNYKKDPYTKHNPCNTICCRQDLYYMTPVPAGCYDSKVADINMAAKFTAYAINGPPVEKGLPIFSWVHFNETTHQGLPESYNFDFVTMKPVL
What is the function of this protein?
May cause hemolysis.
What are the official names of this protein?
Phospholipase-B 81, PLB.
What is the protein family that this protein belongs to?
Belongs to the phospholipase B-like family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUVB_FRAAA
Sequence: MSADGLVSAAASAEEQAFEAGLRPRTLTEFVGQRKVREQLSIMLEGAQARGRPPDHVLLSGPPGLGKTSLAMIIAEELAVPLRMTSGPAIERAGDLVAILTALSPGEVLFLDEIHRIARPAEELLYAAMEDFRVDVILGKGPGATAIPLDVAPFTLVGATTRSGLLTGPLRDRFGFTAHLDFYAPDELARVLTRSAGLLGVSLTEDGAAEVAGRSRGTPRIANRLLRRVRDYAEVRADGVVTRDVARAALRIYDVDGLGLDRLDRAVLEALVGRFGGGPVGLTTLAVSVGEEPETVEDVAEPFLLRAGLLIRTSRGRIATPAAFEHLGLEPVADPLGRSQAPLFSNTGLLAEGGLLPEDGLHPGGG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: OBG_AGRVS
Sequence: MKFLDEAKVYIRSGDGGAGAVSFRREKFIEFGGPDGGDGGRGGDVWVEAVNGLNTLIDFRFQQHFKATVGTHGMGRNRTGANGEHVTLKVPVGTQIFEEDAETLIVDMVTEGQRFRLAAGGNGGFGNAHFKSATNQAPDWANPGLEGEEKTIWLRLKLIADAGLVGLPNAGKSTFLAAVTRARPKIANYPFTTLHPNLGVATVDEREFILADIPGLIEGAHEGVGIGDRFLGHVERTRVLLHLVSAQEEDVAKAYTTVAHELEAYDGGLEDKPEIVALSQIDVLDEDELKKKLKALQKACSKKPMMISAITGKGMLEVLRALRDVIVENRSYDDETISQRPKKHRHKLEDRPQHENGPEESEEGEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ODAD1_BOVIN
Sequence: MPFGLSAGSTRSEDGSEAFLEGMVDWELSRLQRQCKVMEDERRAYSKEVHQRINKQLEEIQRLEGVRHKLRVQISIAQSQVRRLRDSERLESMGHLLKCQVRVQAEVKELQAQNQALDREIQEWESRNSAHSKNARSPGCVQHDKVKSQRRIKSLENQLDKVICRFDIQLAQNATLREELDLLRIERNRYLNVDRKLQKEIQLLKDSVRNLMVSSTSAYTVREEAKAKLGMLRERAEKEVAQNETEVQILQRQIAHLEQLHHFLKLKNGDRQPDSAIVEKREQRAREVAEGLRKTSQEKLVLRYEDALNKLSQMTGESDPDLLVEKYLELEERNFAEFNFINEQNSELEHLQEEIKEMQEALVSGRRSEEDRRAQQEQQRAELQQRVDDVHSEADDLEARYHNFREQLEKLKTNIQHLFTRAQCDSTLINDLLGIKTHMRDRDISLFLSLIEKRLVQLLTVQAFLETQVVVMFNAALMVLGQSSEDFPKKVAPPQPPDNLEDPPGFEAKDDYPLSKEELLSSVMKAEQHLKELVESIKVESTPSMTSSTQKVSSSSRLVTQRPSQVPGSIMSHRTSGILVSSGGRATSSNVGHVTFGDSSATTGGLMSSRGSIPGRVTFRSPNSSSYLGSTGYVGSSRDHDSFEASKGPGSESSGGLGSSPGPASSPGPASSTGQASSTSKDSQSNY
What is the function of this protein?
Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule.  Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules.
What are the official names of this protein?
Outer dynein arm-docking complex subunit 1.
What is the protein family that this protein belongs to?
Belongs to the ODA1/DCC2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, cilium axoneme.
Protein: HKT_AEDAE
Sequence: MKFTPPPSSLRGPLVIPDKIMMGPGPSNCSKRVLAALNNTCLSNFHDELFQVIDEVKDGLRYIFQTENRTTMCITGSAHTGMEALLCNLLEEGDIVLIANNGIWAERAINMATRYGADVRVLGGPADKPFSMTDFKKAIEQHRPKCLFVVHGDSSSGLLQPLEGLGKICHDYDCLLLVDAVASLCGVPFYMDKWEIDGVYTGSQKVLGAPPGITPISISPKALEVIRSRKTPSKVFYWDLLILGNYWGCYDEQKRYHHTVPSNLIFALREAIAQIAEEGLEPVIRRRQECAEQMYRGLQAMGLEIFVKDPEYRLPTVTCIMIPKGVNWWKVSEYAMNNFSLEIQGGFGPTMGIAWRAGIMGESSTLQRVNFYLYAFKESLKATHPDYVFEKKNGQTNGTK
What is the function of this protein?
Catalyzes the pyridoxal 5'-phosphate-dependent transamination of both 3-hydroxykynurenine and L-kynurenine to xanthurenic acid and kynurenic acid, respectively, preferentially using the alpha-ketoacid pyruvate, glyoxylate or oxaloacetate as the amino group acceptor (PubMed:11880382, PubMed:12220660).  The affinity and catalytic efficiency for 3-hydroxykynurenine is higher than for L-kynurenine (PubMed:12220660).  Involved in the detoxification of cytotoxic metabolite 3-hydroxykynurenine generated by the hydroxylation of L-kynurenine, an intermediate in the tryptophan catabolism pathway (PubMed:11880382, PubMed:12220660).  Also catalyzes, although with a lesser efficiency, the transamination of alanine with glyoxylate as an amino group acceptor (PubMed:11880382).  May play a role in the detoxification of glyoxylate, a toxic plant metabolite from the diet (Probable).
What are the official names of this protein?
3-hydroxykynurenine transaminase, 3-hydroxykynurenine transaminase and alanine--glyoxylate aminotransferase, Ae-HKT/AGT, Alanine--glyoxylate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: PETL_ORYNI
Sequence: MLTITSYFGFLLAALTLTLALFIGLNKIRLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CA761_CONIN
Sequence: GCCSHPPCNVNNPHICG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin In1761.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ACEK_SALPB
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKSRIHLYDHHVGLVVEQLRCITDGKSTDADFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFFPDHGWELLLMRILSDLPLRLPWQNKSRDIRYIIAHLTETLGEDALPRCHVQVANELFYRNKAAWLVGKLTTPDGTLPFLLPIHRTDEGELFVDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLCYLAESDEKFIEAPGIRGMVMLVFTLPGFDRVFKIIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLDKRQIDPALMALLRQEVPEKITDLGEHIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPARYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQTRIKEGHVEDVYAYRRRQRFSVRYGAISSTANSS
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MVP_CMVM4
Sequence: MAFQGTSRTLTQQSSAATSDELQKILFSPDAIKKMAAECDLGRHHWMRADNAISVRPLVPEVTHGRIASFFKSGYDAGELCSKGYMSVPQVLCAVTRTVSTDAEGSLRIYLADLGDKELSPIDKQCVTLHNHDLPALVSFQPTYDCPMETVGNRKRCFAVVVERHGYVGYTGTTASVCSNWQARFSSKNNNYTHIAAGKTLVLPFNRLAEQTKPSAVARLLKSQLNNIESSQYVLTDSKINQNARSESEELNVESPPVAIGSSSASRFESFRPQVVNGL
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity).
What are the official names of this protein?
Movement protein, MP, Protein 3A.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles into long tubular structures at the surface of the infected protoplast.
Protein: RNAS9_SYMSY
Sequence: MMRTLITIHPLPLLLLLQQLLQPVQFQEVDTDFDFSEDKKEEFEEYLEQFFSTGPTRPPTKEKVKRRVLIEPGMPLNHIEYCNHEIMGKNVYYKHRCVAEHYFLLMQYDELQNICYNRFVPCKNGIRKCNRSKGLVEGVYCNLTEAFEIPACKYESFYRKGYVLITCAWQNELQKLIPHTINDLVEPSEHRSFLSEDGVFVIPP
What is the function of this protein?
Does not exhibit any ribonuclease activity.
What are the official names of this protein?
Inactive ribonuclease-like protein 9.
What is the protein family that this protein belongs to?
Belongs to the pancreatic ribonuclease family.
What are the subcellular locations of this protein?
Secreted.
Protein: EPB41_MOUSE
Sequence: MTTEKSLAAEAENSQHQQQKEEGEGATNSGQQETQLEEASQAAAAEGSDQGEQKLKASNGDTPTHEDLTKNKERTSESRGLSRLLSSFLKRPKSQVSEEEGREVESEKEKGEGGQKEIELGNSLDEDIILKAPIAAPEPELKTDPSLDLHSLSSIETQPAQEEHREDPDSETKEGEGIEECSGTEVKEDPESRAEREPEASQKPVRRHRNMHCKVSLLDDTVYECVVEKHAKGQDLLKRVCEHLNLLEEDYFGLALWDSATSKTWLDSAKEIKKQVRGVPWNFTFNVKFYPPDPAQLTEDITRYYLCLQLRQDIVAGRLPCSFATLALLGSYTIQSELGDYDPELHGMDYVSDFKLAPNQTKELEEKVMELHKSYRSMTPAQADLEFLENAKKLSMYGVDLHKAKDLEGVDIILGVCSSGLLVYKDKLRINRFPWPKVLKISYKRSSFFIKIRPGEQEHYESTIGFKLPSYRAAKKLWKVCVEHHTFFRLTSTDTIPKSKFLALGSKFRYSGRTQAQTRQASALIDRPAPHFERTASKRASRSLDGAAAAESTDRSPRPTSAPAIAQSQVTEGPGAPIKKTPKEAVKVEEKRGEEPAEPAEPEPTEAWKVEKTHTEVTVPTSNGDQTQKLAGKGEDLIRMRKKKRERLDGENIYIRHSNLMLEDLDKSQEEIKKHHASISELKKNFMESVPEPRPSEWDKRLSTHSPFRTLNINGQVPTGDGPPLVKTQTVTISDTANAVKSEIPTKDVPIVHTETKTITYEAAQTEDSNGDLDPGVLLTAQTITSETTSSTTTTQITKTVKGGISETRIEKRIVITGDADIDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEISEE
What is the function of this protein?
Protein 4. 1 is a major structural element of the erythrocyte membrane skeleton.  It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction.  Recruits DLG1 to membranes.  Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
What are the official names of this protein?
Protein 4.1, P4.1, 4.1R, Band 4.1, Erythrocyte membrane protein band 4.1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
Protein: AQP6_HUMAN
Sequence: MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISVALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
What is the function of this protein?
Forms a water-specific channel that participates in distinct physiological functions such as glomerular filtration, tubular endocytosis and acid-base metabolism.
What are the official names of this protein?
Aquaporin-6, AQP-6, Aquaporin-2-like, Kidney-specific aquaporin, hKID.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Protein: TIG_YERE8
Sequence: MQVSVETTQGLGRRVTITVAADSIEKAVKSELVKAAKNVRIDGFRKGHVPMNIVEQRYGASVRQDVLGDLMQRNFVDAIIKEKINPAGAPNYVPGQYKEGEDFTYSVEFEVYPEVELKDLESIEVEKPVVEVNDADVDTMLETLRKQQATWKETDAAATAEDRATLDFTGSIDGEVFEGGKATDFVLAMGQGRMIPGFEEGVIGHKAGEEFTIDVNFPEDYHAENLKGKSAKFDIVLKKVEVRELPELTEEFIKRFGVADGSVAGLRAEVRKNMERELKGAVRNRVKTQAIDGLVSANEIDVPAALVEGEIDVLRRQAAQRFGGNEKQAAELPRELFEEQAKRRVVVGLLLGEVISQHELKADEDRVKALIEEMASAYEDPQEVIEFYSKNKELMNNMRNVALEEQAVETLLSKAKVTEKPTTFSELMNQTTTA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.