PharMolix/UniProtQA huggingface dataset:
Protein: HINT1_MOUSE
Sequence: MADEIAKAQVAQPGGDTIFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVADDDDESLLGHLMIVGKKCAADLGLKRGYRMVVNEGADGGQSVYHIHLHVLGGRQMNWPPG
What is the function of this protein?
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (By similarity).  Hydrolyzes adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate) (By similarity).  Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester (By similarity).  Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide (By similarity).  In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1 (By similarity).  Modulates p53/TP53 levels and p53/TP53-mediated apoptosis.  Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex (By similarity).  Also exhibits SUMO-specific isopeptidase activity, deconjugating SUMO1 from RANGAP1 and RGS17 (PubMed:31088288).
What are the official names of this protein?
Adenosine 5'-monophosphoramidase HINT1, Desumoylating isopeptidase HINT1, Histidine triad nucleotide-binding protein 1, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1, PKCI-1.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPD_SALAI
Sequence: MQAATSRESYRIAGDRLDAYVRGAEPSAVAATADELLSVADLIRREPRLRRALADPARSGADRAALLTGILSGKVGADALDLSTTLVAGRWSAPSELLDGAERLGVAALLAAADKAGDLGEVEDELFRFGQVVAGQSALSNALSDPAAPVEQRATLAGELLTGKARPVTVRLVEVALGGFGGRSFVGALTRLVELAADRRDRQVAYVTVAAPLGEEEERRLGASLSAIYGREVSVKQSVDPEVLGGVSVRVGSDLYDGTVLRRLNETRNALAKR
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: Y1135_CALS4
Sequence: MAGHSKWANIKHKKEKMDAKKGRIFTKLTKDIIKAAKEGGGDPETNSKLKLAIERAKAFNLPSENIQRAIKRGTGELGGAKLEEVIYEGYGPAGTAIIVEALTDNKNRTAGEIRHIFDRNGGTLGAAGSVTWMFDKVGVIVVEKTDSINEEDLMMVAIEAGAEDFSADEGEFEIITDPSNFQEVREAIEKAGYKISEAEITMLPKNTIKLSPEDYEKFEKLIDKLEDNDDVQNVYHNVELEDE
What are the official names of this protein?
Probable transcriptional regulatory protein TTE1135.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK2_TRIV2
Sequence: MPKVGIIYNDIKPVAGRVAIELKDKLTTAGWDVSITSSIGGILGYSNPESPVCHTPIDGLTPPGFDSEMKFAIVLGGDGTVLAASRQVAPCGIPILAINTGHMGFLTETYLNQLPQAIDQAIAGEYEIEERAMLTVKVLRGESVLWEALCLNEMVLHREPLTSMCHFEIAVGRHAPVDIAADGVIVSTPTGSTAYSLSAGGPVVTPGVPALQLVPICPHSLASRALVFPDTEPVNIYPVNIPRLVMVVDGNGGCYIFPEDRVYLERSPYSVKFIRLQPPEFFRILREKLGWGLPHIAKPTSVELP
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase 2, ATP-dependent NAD kinase 2.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCYB1_BOVIN
Sequence: MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVRIIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATIYPGMRAPSFRCTDADKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRISPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQLQPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKSECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQVDGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTYRCLMTPENSDPQFHLEHRGPVSMKGKKEPMQVWFLSRKNTGTEETEQDEN
What is the function of this protein?
Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
What are the official names of this protein?
Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit.
What is the protein family that this protein belongs to?
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein: TDG_SCHPO
Sequence: MNDIETRDTGTKNDNSSEFNLSVKSHKRKRSFDDENLELEESREETSGGILKKAKTQSFSESLERFRFAHAGSNNEYRKTDVVKNSDTDNGLLKSAVETITLENGLRNRRVNVTKKSTLKASVKKSTLKKKNEVDPALLQGVPDYICENPYAIIVGLNPGITSSLKGHAFASPSNRFWKMLNKSKLLEGNAEFTYLNDKDLPAHGLGITNLCARPSSSGADLRKEEMQDGARILYEKVKRYRPQVGLFISGKGIWEEMYKMLTGKKLPKTFVFGWQPEKFGDANVFVGISSSGRAAGYSDEKKQNLWNLFAEEVNRHREIVKHAV
What is the function of this protein?
Removes uracil from G/U mispairs in ssDNA.  Also corrects G/G mispairs.  Does not catalyze the removal of thymine from G/T mispairs.
What are the official names of this protein?
G/U mismatch-specific uracil DNA glycosylase, Uracil mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTS_COPPD
Sequence: MEISASLVKQLRDETGAGFMECKKALEETGGDLEKAKLVLKEKGLARAEKKIGRAASQGLIHAYIHGEGKLGVLVEVNCETDFVARTDDFKELVHEIALQIAGMAPEYVAVEDVPEEVIEQEKEIYRKQAENEGKPAEIIDKIVEGKLQNFYKSKVLLEQPYVRDDSKTIKDLIKEKIALLGENIVVRRFVRWTLGE
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HPT1_ORYSJ
Sequence: MDSLRLRPSLLAARAPGAASLPPLRRDHFLPPLCSIHRNGKRPVSLSSQRTQGPSFDQCQKFFGWKSSHHRIPHRPTSSSADASGQPLQSSAEAHDSSSIWKPISSSLDAFYRFSRPHTVIGTALSIVSVSLLAVENLSDVSPLFLTGLLEAVVAALFMNIYIVGLNQLFDIEIDKVNKPTLPLASGEYSPATGVALVSAFAAMSFGLGWAVGSQPLFLALFISFILGTAYSINLPFLRWKRSAVVAALCILAVRAVIVQLAFFLHIQTFVFRRPAVFTRPLIFATAFMTFFSVVIALFKDIPDIEGDRIFGIKSFSVRLGQKKVFWICVGLLEMAYCVAILMGATSACLWSKYATVVGHAILAAILWNRSRSIDLTSKTAITSFYMFIWKLFYAEYLLIPLVR
What is the function of this protein?
Involved in the synthesis of tocopherol (vitamin E).  Catalyzes the condensation of homogentisate and phytyl diphosphate to form dimethylphytylhydroquinone (By similarity).
What are the official names of this protein?
Probable homogentisate phytyltransferase 1, chloroplastic, Vitamin E pathway gene 2-1 protein, OsVTE2-1.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SRRA_STAAS
Sequence: MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAMENNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVKPFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLTPKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAAHMIQTVWGVGYKFEVKSNDEPAK
What is the function of this protein?
Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation.  Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate (By similarity).  Functions as a transcription regulator by direct binding to promoter regions of target genes (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein SrrA, Staphylococcal respiratory response protein A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_COXBR
Sequence: MSEKRVEKKLIHYVKKALNDYRMINTGDRVMVCLSGGKDSYTLLSLLNSIRIEGNYKFDIFAFVLDQSQPGWDDSALRGWLDDKKIPYEILTRDTYSIVKEKIPAGKTYCSLCSRLRRGIIYRYAEEQGFSKIALGHHRDDLIQTLLMSVFYNGQIRSMPPKLLSDNRRHVLIRPLAYCQERDIIKYAMEQQFPLIPCNLCGSQKNLMRQRVKRLISDLAKENPKVPSNMLRALSNIKPSQLMDHELWNFRELNVD
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU3M_HORSE
Sequence: MNLMLTLLTNTLLASLLVLIAFWLPQLNIYAEKTSPYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQTTNLNTMLIMALVLISLLAISLAYEWTQKGLEWTE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YBGC_HELPY
Sequence: MRCRVYYEDTDSEGVVYHANYLKYCERARSEFFFKQNVLPENEEGVFVIRSIKADFFTPASLGQVLEIRTQIKELRKVFVVLFQEIYCIQNASLEPMKPFKVFASEIKFGFVNRSTYSPIAIPKLFKELLNAI
What is the function of this protein?
Thioesterase that may be involved in phospholipid metabolism.  Displays acyl-CoA thioesterase activity with lauroyl-CoA (C12:0), myristoyl-CoA (C14:0), palmitoyl-CoA (C16:0), stearoyl-CoA (C18:0) and benzoyl-CoA, catalyzing the hydrolysis of the thioester bond.  Has low activity with butyryl-CoA and octanoyl-CoA.
What are the official names of this protein?
Acyl-CoA thioesterase YbgC.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.
Protein: YL717_MIMIV
Sequence: MSSLVLIPCALLTQGIYAGLIGAISTVTMSACSAIRSIYNYKNADVNHIIKLLDIERKLIIIQSILNITTNSDTLSGKTPLELTDLEKTHVFELIKKKTDLTKDPIQLCLIFLHEAIENIHKDLSVIHEKIDYHNNKWFNYWRSLNIKHLITNLEADIIIMNERFDYLMKISAFLDHIKDSKKQINSMRWNLSNPIDRKLLFQSLD
What are the official names of this protein?
Uncharacterized protein L717.
Protein: VE2_HPV58
Sequence: MEEISARLSAVQDKILDIYEADKNDLTSQIEHWKLIRMECAIMYTARQMGISHLCHQVVPSLVASKTKAFQVIELQMALETLNASPYKTDEWTLQQTSLEVWLSEPQKCFKKKGITVTVQYDNDKANTMDYTNWSEIYIIEETTCTLVAGEVDYVGLYYIHGNEKTYFKYFKEDAKKYSKTQLWEVHVGSRVIVCPTSIPSDQISTTETADPKTTEATNNESTQGTKRRRLDLPDSRDNTQYSTKYTDCAVDSRPRGGGLHSTTNCTYKGRNVCSSKVSPIVHLKGDPNSLKCLRYRLKPFKDLYCNMSSTWHWTSDDKGDKVGIVTVTYTTETQRQLFLNTVKIPPTVQISTGVMSL
What is the function of this protein?
Plays a role in the initiation of viral DNA replication.  A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity.  Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA.  E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome.  Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box.  Repression occurs by sterically hindering the assembly of the transcription initiation complex.
What are the official names of this protein?
Regulatory protein E2.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E2 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: PANB_ACET2
Sequence: MNDKFTTASFLESKKQGRKITMLTAYDYPTAKILDEAGVDSILVGDSLGMVVLGYEDTTRVTMDDMVHHTKAVVRGVKRAMVVADMPFLSYHTGKNDSVRNAGRLVSEGGCKAVKLEGGEDIIENVKAIISAGIPVVGHLGYTPQSINVFGGHKAQGKTIDTAKKIYRDALLLQKAGVFAVVLECVPYKLAAFISKRLDIPTIGIGSGPDCDGQVLVIHDLTGMFKDFTPKHVKKYAEIGETVSTAVKSYIDEVKNGVFPTEKNSFKVDDWIIDELDKVRFDI
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMU_DICNV
Sequence: MLHKSVLGLVLAAGMGTRMRSNQSKALQMIGGKPMIAHLLASMQETNLLTHQAIVYGYRGEALQAALKADFPNVFWVKQEQQLGTGDAVKSATALIEQHDLTLIAFADIPLIRPHTLQQLLHSAAQHGFAILTAQMENPFGYGRIIHDETGGVCAIVEEKDANREQKNIREINVGVMAVKQEWLLTYLPRLENHNAQGEFYLSDLVELIARDGHFIESFCLESADEAMGANDRAQLAALEAVYRQRKVQELFAQGVTLIDPNRIDIHGTVIAGADVVIEPNVFLKGTVVIGDGVTIESGCCLKDCEIGRNTIIRSHSVIDTATIGAQADIGPFARIRPQTVIADGGKIGNFVEIKAAKIGQESKVNHLSYIGDAHIGAKVNVGAGTITCNYDGAAKHPTFIGDHVFIGSNTALVAPVTIKNGATIGAGSVITRDVAADTLALTRPKLTQIEHWRRPQKKKEHKNDA
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAE_XYLFA
Sequence: MSVYAVGLTGGIACGKSLLAQLFEALNTTVVDADIIARQVVEPGPVLNCIVARFGSKILRADGCLDRRFLRQRVFADVAERKALEAIVHPVIRSGLKQAAAAAAGPYVLVVIPLLAEAGGRIGYPWLQRILVVDAIPEVQHARLMQRDSIDAEQASLMIAAQIGRKERLAIADDIVFNDGDPVHLGGQVCNLDARYRALASVFSDVD
What is the function of this protein?
Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
What are the official names of this protein?
Dephospho-CoA kinase, Dephosphocoenzyme A kinase.
What is the protein family that this protein belongs to?
Belongs to the CoaE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y293_TREPA
Sequence: MRMTRVRSLCLAYARCVRLGVFRCISLRGWAPYRAVETVLVQSALTSVERLHEMFRVY
What are the official names of this protein?
Uncharacterized protein TP_0293.
Protein: HLDE_DESAL
Sequence: METENIHSFDVSLFSSCRVLVVGDMMIDEYLWGEVSRISPEAPVQVVEVKKTTSTLGGAGNVVNNLTALGAKVSVAGVMGGGKAGDLLNGKLTALGVNTEGLLVDQGRATTRKTRVIGANQQMLRIDRESKQEISEEQVQAIVRFAQNQIPQCDLVIASDYGKGVLTRSLMEELAKICKTAGKALIVDPKGMDYSKYKGATCITPNKKEASQASGVEIKDQASLERAAAKLLEIAGAEKILITLGKDGMALFSPGEEPFRVHAQARQVFDVSGAGDTVISVLGLSLAAGASYKTAAALANTAAGIVVAKVGTATVDQAELKAQLQDQPIAYQAKLKPLQELKSALENLRRQGKKIILTNGCFDLLHEGHINLLEQSRKLGDVLVVAVDDDESVRMVKGQGRPIIRERERVKIISAMTGVDFVTVFSTNQLDELIRAVKPDILTKGGNYKPDQVLGHEIVEELGGRIVLIPDASDVSSTRIIQDIRNGRG
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: TAD1_ARATH
Sequence: MEEDWGKTVSEKVISAYMSLPKKGKPQGREVTVLSAFLVSSPSQDPKVIALGTGTKCVSGSLLSPRGDIVNDSHAEVVARRALIRFFYSEIQRMQLTSGKSNEAKRQRIDSETSSILESADSSCPGEVKYKLKSGCLLHLYISQLPCGYASTSSPLYALKKIPSTQVDDSLLVQASDICSSRHSDVPEIGSNSNKGNGSQVADMVQRKPGRGETTLSVSCSDKIARWNVLGVQGALLYQVLQPVYISTITVGQSLHSPDNFSLADHLRRSLYERILPLSDELLTSFRLNKPLFFVAPVPPSEFQHSETAQATLTCGYSLCWNYSGLHEVILGTTGRKQGTSAKGALYPSTQSSICKQRLLELFLKETHGHKRESSKSKKSYRELKNKATEYYLMSKIFKGKYPFNNWLRKPLNCEDFLIN
What is the function of this protein?
Involved in RNA editing.  Catalyzes the specific deamination of adenosine-37 in the cytosolic tRNA-Ala.  Generates inosine at the position 3'-adjacent to the anticodon tRNA-Ala.
What are the official names of this protein?
tRNA-specific adenosine deaminase TAD1, AtTAD1, tRNA-specific adenosine-37 deaminase TAD1.
What is the protein family that this protein belongs to?
Belongs to the ADAT1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TSAD_ANADE
Sequence: MTRVLAIETSCDETAAAVVEDGRRALSDVVSTQIDIHRRWGGVVPELASRNHVVQVMPVVDEALTRSGVGPEGLDAVAVTSGPGLVGALLVGVQAAKALALAWGKPLVGVNHLEGHLVAAFLAEVPPAFPYLGLVVSGGHTSLYAAHGFGDYRLLGQTRDDAAGEAFDKGAKLLGLPYPGGVAIDRLAKEGDPAAIRFPKAIVKGADLDFSFSGLKTALLHHVKKHGVPEGPALADLCASYQEAIVRALVEKAFRAARRLQFERLVLAGGVAANSRLRAAATARAAEYEGMSVFIPPVRLCTDNAAMIAVAGTHALLRGERAGPDLNADPAWRL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_MICDP
Sequence: MLSPRRTKFRKQQRGRMEGLAHRGSTLNFGDFALQAQEPAWITSRQIEASRRAMTRYIRRGGQIWIRIFPDKPVTMRPAETRMGSGKGNPEFWVAVVKPGRILFEIAGVSEEVAREAMRLAAYKLPIKTKFIVRPQVQEQE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: SYV_HAEI8
Sequence: MTQKFEMADRFNPSAVEQALYQHWEESGYFKPSENENAPSYCIAIPPPNVTGSLHMGHAFQQTLMDTLIRFNRMEGHNTLWQAGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFINKIWDWKAYSGGTISQQMRRLGNSIDWERERFTMDDGLSNAVKEVFVRLHEEGLIYRGKRLVNWDPKLHTAISDLEVENKESKGSLWHFRYPLANGAKTADGKDYLVVATTRPETMLGDTAVAVHPEDERYQSLIGKTVVLPLANREIPIIADEYVDREFGTGVVKITPAHDFNDYEVGKRHNLPMVNVLTLNANIRDEAEIIGTDGKPLAGYEATIPADYRGLERFAARKKIVADFEALGLLDEIKPHDLKVPYGDRGGVPIEPMLTDQWYVSVKPLADVAIKAVEDGEIQFVPKQYENLYFSWMRDIQDWCISRQLWWGHRIPAWYDAEGNVYVARNEEEVRSKYNLDSAVELKQDEDVLDTWFSSGLWTFSTLGWPEQTKELKMFHPTDVLITGFDIIFFWVARMIMFTMHFVKDENGKPQVPFKTVYVTGLIRDEQGQKMSKSKGNVLDPIDMIDGISLEDLLEKRTGNMMQPQLAEKIAKATRKEFADGIAAHGTDALRFTLAALASNGRDINWDMKRLEGYRNFCNKLWNASRFVLTNEKLDLSEGEIEFSLADRWIQSEFNRTVETFRNSLSQYRFDLCANAIYEFTWNQFCDWYLELTKPVFANGNAAQIRAASQTLVHVLEKLLRLAHPLIPFITEEIWQKVKGFVGITADSIMLQPFPQVEENGFDLEAEAEIEWLKEVIVAVRNIRAESNIAPSKGLDLLFRNLSAENAKILEKQTALLKAMAKLDNVQVLAANEAAPLAVAKLVGNAELLVPMAGFINKEAELARLTKEIEKYQNEVKRIENKLSNESFVAKAPEAVIAKEREKQAEYQSGLEKIQEQYKAIEAL
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNMT4_ARATH
Sequence: MEMETKAGKQKKRSVDSDDDVSKERRPKRAAACTNFKEKSLRISDKSETVEAKKEQILAEEIVAIQLTSSLESNDDPRPNRRLTDFVLHDSEGVPQPVEMLELGDIFIEGVVLPLGDEKKEEKGVRFQSFGRVENWNISGYEDGSPVIWISTALADYDCRKPSKKYKKLYDYFFEKACACVEVFKSLSKNPDTSLDELLAAVSRSMSGSKIFSSGGAIQEFVISQGEFIYNQLAGLDETAKNHETCFVENRVLVSLRDHESNKIHKALSNVALRIDESKVVTSDHLVDGAEDEDVKYAKLIQEEEYRKSMERSRNKRSSTTSGGSSRFYIKISEDEIADDYPLPSYYKNTKEETDELVLFEAGYEVDTRDLPCRTLHNWTLYNSDSRMISLEVLPMRPCAEIDVTVFGSGVVAEDDGSGFCLDDSESSTSTQSNDHDGMNIFLSQIKEWMIEFGAEMIFVTLRTDMAWYRLGKPSKQYAPWFGTVMKTVRVGISIFNMLMRESRVAKLSYANVIKRLCGLEENDKAYISSKLLDVERYVVVHGQIILQLFEEYPDKDIKRCPFVTSLASKMQDIHHTKWIIKKKKKILQKGKNLNPRAGIAPVVSRMKAMQATTTRLVNRIWGEFYSIYSPEVPSEAINAENVEEEELEEVEEEDENEEDDPEENELEAVEIQNSPTPKKIKGISEDMEIKWDGEILGKTSAGEPLYGRAFVGGDVVVVGSAVILEVDDQDDTQLICFVEFMFESSNHSKMLHGKLLQRGSETVLGMAANERELFLTNECLTVQLKDIKGTVSLEIRSRLWGHQYRKENIDVDKLDRARAEERKTNGLPTDYYCKSLYSPERGGFFSLPRNDMGLGSGFCSSCKIRENEEERSKTKLNDSKTGFLSNGIEYHNGDFVYVLPNYITKDGLKKGSRRTTLKCGRNVGLKAFVVCQLLDVIVLEESRKASKASFQVKLTRFYRPEDISEEKAYASDIQELYYSQDTYILPPEAIQGKCEVRKKSDMPLCREYPILDHIFFCEVFYDSSTGYLKQFPANMKLKFSTIKDETLLREKKGKGVETGTSSGMLMKPDEVPKEKPLATLDIFAGCGGLSHGLENAGVSTTKWAIEYEEPAGHAFKQNHPEATVFVDNCNVILRAIMEKCGDVDDCVSTVEAAELAAKLDENQKSTLPLPGQVDFINGGPPCQGFSGMNRFSHGSWSKVQCEMILAFLSFADYFRPKYFLLENVKKFVTYNKGRTFQLTMASLLEMGYQVRFGILEAGTYGVSQPRKRVIIWAASPEEVLPEWPEPMHVFDNPGSKISLPRGLRYDAGCNTKFGAPFRSITVRDTIGDLPPVENGESKINKEYGTTPASWFQKKIRGNMSVLTDHICKGLNELNLIRCKKIPKRPGADWRDLPDENVTLSNGLVEKLRPLALSKTAKNHNEWKGLYGRLDWQGNLPISITDPQPMGKVGMCFHPEQDRIITVRECARSQGFPDSYEFSGTTKHKHRQIGNAVPPPLAFALGRKLKEALYLKSSLQHQS
What is the function of this protein?
Maintains chromatin CpG methylation that plays a role in genomic imprinting, regulation of embryogenesis and seed viability.  Required for proper patterns of CG DNA methylation in dividing cells (By similarity).
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase 4, DNA methyltransferase 4, DNA methyltransferase IIa, DMT02, MET02.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HIS7_BRUA1
Sequence: MTAESTRKASIERSTKETSIAVSVDLDGVGKFDITTGVGFFDHMLEQLSRHSLIDMRVMAKGDLHIDDHHTVEDTGIALGQAVAKALGERRGIVRYASLDLAMDDTLTGAAVDVSGRAFLVWNVNFTTAKIGTFDTELVREFFQAFAMNAGITLHINNHYGANNHHIAESTFKAVARVLRAALETDPRQKDAIPSTKGSLKG
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.