PharMolix/UniProtQA huggingface dataset:
Protein: CBP4_DEBHA
Sequence: MSQKPLWYRWARVGVVGFSIIATGSLLFKYTVPTDEQLIAKFSPEIRAEYERNREIRQKEQQELMKIARETAASDDPIWKTGRIKSPFEKDGRNTDPKLVDIEKYNRERGDEFKKSEVERAQQELREAEELVSQKKGWFSRK
What is the function of this protein?
Essential for the assembly of ubiquinol-cytochrome c reductase.  It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b (By similarity).
What are the official names of this protein?
Assembly factor CBP4, Cytochrome b mRNA-processing protein 4.
What is the protein family that this protein belongs to?
Belongs to the CBP4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SYL_DESVV
Sequence: MKYDHQSIETRWQKKWEDSGIFQCDTEADKPKYYVLEMFPYPSGNIHMGHVRNYSIGDVVARFKRMQGFNVLHPMGWDAFGLPAENAAIKNGTHPAKWTFANIDNMRSQLKRLGYSYDWQREVATCTPEYYRWEQLFFLRFLEKGLVYRKKAAQNWCPKCHTVLANEQVIEGLCWRCDSAVEQKELTQWFLRITDYAEELLADLSKLENGWPERVLSMQRNWIGKSTGAEIRFALDGRDDSITVFTTRPDTIFGATFMSIAPEHPLVEELIDGKPQADDVRAFVERIRNMDRIDRQSDTLEKEGVFTGAYCVNPFTGRKMPIWVANFVLAEYGTGAVMAVPAHDQRDFEFARKYDLPMQVVIQPQGETLDPATMSAAWTEAGALVNSGNFDGLANEDAKQRIADDLETTGNGRRTINYRLRDWNISRQRYWGAPIPVIYCDACGVVPEKEENLPVVLPLDVKTHDDGRSPLPHTPAFYECTCPVCGGKARRETDTMDTFVESSWYFARYTDATNDKAPFTPDALRYWLPVDQYIGGVEHAILHLLYSRFFTKALRDCGFIELDEPFANLLTQGMVLMDGSKMSKSKGNVVDPTEMIARYGADTVRLFCLFAAPPERDFDWSESGIEGSYRFVGRVWRLVEELREHLLAVGACSSTAEDAKTPVARELRLKEHATVRKAGDDLNDRFQFNTAIAAVMELVNALYLAKDELVADESGRKVLSSAVSTVLTLLSPFTPHLSEELWALLGHTESVSTLPWPRWKEDALVRDTVTLVVQVNGKLRGKLDIPADASREEVETLALNEPNVLRYLEGVTVRKVVVIPGKLVNVVVS
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAN2_BPP22
Sequence: MLTRLSKLSALMFLLGVSACKSPPPVQSQRPEPAAWAMEKAQDLQQMLNSIITVSEVESTG
What is the function of this protein?
Component of the spanin complex that disrupts the host outer membrane and participates in cell lysis during virus exit.  The spanin complex conducts the final step in host lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans.  Host outer membrane disruption is possibly due to local fusion between the inner and outer membrane performed by the spanin complex (By similarity).
What are the official names of this protein?
Probable spanin, outer lipoprotein subunit, o-spanin, Rz1 protein.
What is the protein family that this protein belongs to?
Belongs to the caudovirales o-spanin family.
What are the subcellular locations of this protein?
Host cell outer membrane; Lipid- anchor; Periplasmic side.
Protein: Y184_VIBPA
Sequence: MILKALPNESMPREKLLQRGPQALTDAELLAIFLRTGTQGMNVIELADFLIQDFGSLRQLFSASEQEFCQHKGLGQAKYVQLQAVLEMTQRYLAETLKRGDALTSPEQTKLYLSSILRDRQREAFYILFLDNQHRVIKDEILFEGTLDAASVYPREVVKRALHHNAAALILAHNHPSGVAEPSQADRRITRRLIDALALVDIRILDHFVIGDGESVSFAERGWI
What are the official names of this protein?
UPF0758 protein VP0184.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: MU122_SCHPO
Sequence: MYRKWDLCITRHLLPYIEHSVIPIIALLVLSLIFYILYICFGTTSYILSGIILGAYVNSLFHNNHSVILNIKHPELGEPLKPYQTPLPPELEAPLQLLISKLTQHYINGWYKHVSEDPSFIREVQSTIEYIMRQFYAYVSSQESSHIIYELLKNAISTTTLVLSDLNHFRSKKIPLTEFALRYPESAVSKLLDQASIERTLRAQASAMIVKFSRPEDSACLPLHCLLREVLAMQVFKRITTHCSSPRFVNRCIILYFSSSEDKSDCLAKKNYVNKCLMAKALKDYPVHTNIDPDAGKLSFDDAFYEAHIELHYQFLKEASLNTLIKDKKMLKFIITVRPVHLHVSPWVVYRRYRGFKTLYYLLKKQSARNGRAVPSFPVWRGNTYEKFREGLYFFIEALLHDSHFATNVDVRKFFAKSMRSHPLVDDIYNGFDVDKKHQSSSVPTLPNLTNISRVLSNKTSKSAKPKRSERTGLLSHQSTLAPEPLSQQRDSFELCTTGYRDTGSCTSDDEDSIHEPYRPASTQPTENPPAMPDHNGSPTTEPPKPNAFELKEERLKEIISGGFALVDELCSLNSKLWFFRKSVLTIMKTTVLHGPGRFSAQVERMLKNQIYDKLSNTQLVGDLLTSLILNVWPDEKKAMESHSTRAHRRSTESKISFDSEADSLFEEASKSVPEDPVSVFCDEESDESLRLRAEKTLVENALSENFTLMLGQSTSEESLKIIFELLQEPQFVQGFLAHLLSNALRSII
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 122 protein.
What is the protein family that this protein belongs to?
Belongs to the sorting nexin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: PROA_PROMT
Sequence: MSTNFSVPEPTPQLVKVAESAKEASISLGQSTNKQRCEALTEMANALNDNADEILKANVQDLERSEKEGLNKSLLSRLQLTKTKLKGCIDGVLKVSNLADPIGKRQLHRELNENLILERVTVPLGVLGVIFESRPDALIQIASLAVRSGNGALLKGGSEAKDTNQAIMDSLDKGLRKANVGSGALSLLTTRQESLGLLRLDKFVNLIIPRGSNELVQFIQENTRIPVLGHADGICHLYVDNSVDIDKAISIALDSKIQYPAACNAIETLLIHEDIAEMFLKKGLPIFSSEGVTLKGDTKSQALGVKNKADESDWSKEYLDLILSIKIVRNVNEAIEHIRKYSSRHTEAIVTEDKMVAEKFLSSVDSAGVYHNCSTRFADGFRYGFGAEVGISTQTLPPRGPVGLEGLVTYRYYLRGDGDLVKDFASGDRSFSHIDLPL
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4380_BACCR
Sequence: MEERQITIVDEKGNEHLCEIIFTFDADKFGKKSYVIFSPIGEVDEDGDPIYDAMAYEQNEEEGGVLLPIESEEEWEMVQETFNTIADEQEAE
What are the official names of this protein?
UPF0473 protein BC_4380.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: AMI4_MYCTU
Sequence: MTDADSAVPPRLDEDAISKLELTEVADLIRTRQLTSAEVTESTLRRIERLDPQLKSYAFVMPETALAAARAADADIARGHYEGVLHGVPIGVKDLCYTVDAPTAAGTTIFRDFRPAYDATVVARLRAAGAVIIGKLAMTEGAYLGYHPSLPTPVNPWDPTAWAGVSSSGCGVATAAGLCFGSIGSDTGGSIRFPTSMCGVTGIKPTWGRVSRHGVVELAASYDHVGPITRSAHDAAVLLSVIAGSDIHDPSCSAEPVPDYAADLALTRIPRVGVDWSQTTSFDEDTTAMLADVVKTLDDIGWPVIDVKLPALAPMVAAFGKMRAVETAIAHADTYPARADEYGPIMRAMIDAGHRLAAVEYQTLTERRLEFTRSLRRVFHDVDILLMPSAGIASPTLETMRGLGQDPELTARLAMPTAPFNVSGNPAICLPAGTTARGTPLGVQFIGREFDEHLLVRAGHAFQQVTGYHRRRPPV
What are the official names of this protein?
Putative amidase AmiD.
What is the protein family that this protein belongs to?
Belongs to the amidase family.
Protein: NUON_ALKEH
Sequence: MTVETPDFVMPDFSLALPEIWMLVMACVVLVVDLYSQDSRRGMTFMLTQFTLVVAGVLAIVAHWGEPAVTFSGTYVSDNLAAVLKVAIAGLGFLSFAYCRDYLEDRGLLKGEYFVLGLFSLLGMMIMASAHNLMTVYLGLELLALTLYAMVAFNRDNLRATEAAMKYFVLGAIASGILLYGMSLIYGATGSLNLAEVAVYAGEQGANDWLLLLGMTLVVVGVAFKFGAVPFHTWMPDVYQGAPTTVALFASTAPKVAAVALFVRLLSEGLGPIHDQWQPMIILLAVASLVVGNLAALAQTNIKRMLAYSTASHVGFILLGFIAGTAEGYSTALFYAITYGIMSAGAFGLIILLSHRGFEAENISDFKGLNDRSPAMALMMLLLMFSMTGIPGTVGFYAKWLVIKSVVDVGLVWLAVFAVVFAVIGAFYYLRVLKFVYFDKPETDAPPQTGSPAMRGLLVANGIAVLLLGIFPDSLISACMAAFGVSYG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit N, NADH dehydrogenase I subunit N, NDH-1 subunit N.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HEMA_I86A0
Sequence: MKAKLLVLLCAFTATDADTICIGYHANNSTDTVDTVLEKNVTVTHSVNLLEDSHNGKLCRLKGIAPLQLGNCSIAGWILGNPECESLFSKKSWSYIAETPNSENGTCYPGYFADYEELREQLSSVSSFERFEIFPKESSWPNHTVTKGVTAACSHKGKSSFYRNLLWLTEKNGSYPNLSKSYVNNKEKEVLVLWGVHHPSNIGDQRAIYHTENAYVSVVSSHYNRRFTPEIAKRPKVRGQEGRINYYWTLLEPEDTIIFEANGNLIAPWYAFALSRGFGSGIITSNASMDECDAKCQTPQGAINSSLPFQNVHPVTIGECPKYVRSTKLRMVTGLRNIPSIQSR
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: DNAK_DESVV
Sequence: MGKIIGIDLGTTNSCVYVMEGKDPKCITNPEGGRTTPSVVAFTDKERLVGDIAKRQAVTNPERTVFAVKRLMGRRGDAPEVGRWKEHSPYRIVAGANGDAAVEVQGRPYSAPEISAMILGKLKADAEAYLGETVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAASLAYGFDRKANEKIAVFDLGGGTFDISILEVGDNVVEVRATNGDTFLGGEDFDQRIISYLVDEFRRENGGIDLARDRMALQRLKEAAEKAKKDLSTSMETEVNLPFITADQTGPKHLMMKLSRAKLEKLVEDLVERTVEPCRKALADAGLTAAQIDEVVLVGGMTRMPLVQKRVSEFFGKEPNRSVNPDEVVAMGAAIQGGILAGDVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPTRKSQTFTTAADNQPSVSIHVLQGERPMASDNMTLGRFELTGIPPAMRGVPQIEVSFDIDANGIVNVAAKDLGTGKEQSIRITASSGLSEDEIQRLVKEAEAHADDDKKKQELIEARNQADGLIYGTEKSIRDLGDKLDAALKADIETKVTALRGLLESEDVDAIKKASDELAQASHKLAEQLYKQQAQAGGPEAGAQPEGDAGARKQDDDVVDADYTEVKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL34_PARXL
Sequence: MKRTYQPSVTRRKRTHGFRVRMKTAGGRKVINARRAKGRKRLAI
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: RL23_THEKO
Sequence: MDPYKVIIRPLVTEKAVSLIERENKLTFIVDRRATKQDIKRAVEEMFNVKVAKVNTLVTMKGEKKAYVKLKPEYDASEIAARLGLF
What is the function of this protein?
Binds to 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: GOLS1_ARATH
Sequence: MAPGLTQTADAMSTVTITKPSLPSVQDSDRAYVTFLAGNGDYVKGVVGLAKGLRKVKSAYPLVVAMLPDVPEEHRRILVDQGCIVREIEPVYPPENQTQFAMAYYVINYSKLRIWKFVEYSKMIYLDGDIQVYENIDHLFDLPDGYLYAVMDCFCEKTWSHTPQYKIRYCQQCPDKVQWPKAELGEPPALYFNAGMFLYEPNLETYEDLLRTLKITPPTPFAEQDFLNMYFKKIYKPIPLVYNLVLAMLWRHPENVELGKVKVVHYCAAGSKPWRYTGKEANMEREDIKMLVKKWWDIYDDESLDYKKPVTVVDTEVDLVNLKPFITALTEAGRLNYVTAPSAA
What is the function of this protein?
Galactinol synthase involved in the biosynthesis of raffinose family oligosaccharides (RFOs) that function as osmoprotectants.  Promotes plant stress tolerance such as heat, chilling, salinity and methylviologen (MV), a superoxide radical generating drug, by mediating raffinose accumulation, an osmoprotective substance.
What are the official names of this protein?
Galactinol synthase 1, AtGolS1, GolS-1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 8 family. Galactosyltransferase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ART10_LACTC
Sequence: MSTTVRVVLDPPSNGEFYTLEDVIAGSVVLGLEKSVNIREVMVKLVGQSEAVVRPGDHLENEKPQSLQVPLSDNRSLHEVVKLESSVFPPENVKAAMKGSRKPFKVEKGEYKFPFEFHFPSRPQCIQRHQRKLFTYLKGRTNPKLPPSFNNLLSSKDVLNLNAYFYSLGCIEYFVEATVFTGGDEMWFKPFRSYPALKRTFEFIPSNVAQEHLEDALRENPNTPPQVFRSKFDVTFEGSEQQMWVEVRSKHLRSVYRLDYLFRPSGKKFNQVFLCMLNPLPESADLRVARVELNLIEVVTYLAGNRSNANLSSLRLAGVDTDYKVDLTKCQQTESGFTECHVELSDIYPLDMIRFNEEDYKHNGNRLYSFDSCNIRRRFKFQLFLHWTLNGVDHFQTEVLTNFTNIFCESVTVAEQPPDYMEEQLPKYE
What is the function of this protein?
May regulate endocytosis by recruiting RSP5 ubiquitin ligase activity to specific plasma membrane proteins in response to extracellular stimuli.
What are the official names of this protein?
Arrestin-related trafficking adapter 10.
What is the protein family that this protein belongs to?
Belongs to the ART10 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TP75_TREPA
Sequence: MGTRVRFSFCGIAGVCLLALGFLVSCSLQSSRSATKKSEARRTSYRIGLMTSTGS
What are the official names of this protein?
Protein Tp75.
Protein: MFA4_PORGI
Sequence: MKKYLLYASLLTSVLLFSCSKNNPNEPVEDRSIEISIRVDDFTKTGEAVRYERNQGSAAERLITNLYLLLFDQSGANPAKYYITGNTFTGGTWLPDDMKVKLDMTQSEAGERKVYVVANVDNAVKTALDAVANESDLQTVKRTTAMPWSTDIASPFLMSGNKTHDFLANRLLDNVPLVRAIAKVELNISLSEKFQIVPIIVNGSLSEFKFRYVNFDKETYVVKPTTKPDNLISSANGVWPQITDWTVWGASLNTSPAPDAGTGYTLDANGKVTALRIVTYLNERDSKGATVEVALPRVDDGTLPPPEFGPELYRLPLPDKILRNHWYKYEVEI
What is the function of this protein?
Tip subunit of the minor fimbriae (PubMed:27062925).  These filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome.  They play an important role in invasion of periodontal tissues and are recognized as major virulence factors (Probable).
What are the official names of this protein?
Minor fimbrium tip subunit MfA4, Immunoreactive 32 kDa antigen PG49.
What is the protein family that this protein belongs to?
Belongs to the bacteroidetes fimbrillin superfamily. FimA/Mfa1 family.
What are the subcellular locations of this protein?
Fimbrium. Cell outer membrane. Note=Targeted to the outer membrane as a palmitoylated precursor. The lipid modification is no longer present after proteolytic processing to the mature form.
Protein: SRP72_YEAST
Sequence: MAKDNLTNLLSQLNIQLSQDEHSQVEQTCVKLLDSGCENPADVFRRCLVAVIQQDKYQKALHYLKKFKHIDDKYGRKFALEKLYIFYKLNMPDEFNTLYTAIITDDLDTVLKKDIESLRGILHVRAQYCYKNGLYQEAFKIYQHLASHNEKDQDSQIELSCNERVPLSVATELMNRSPLVTPMDESSYDLLFNESFIMASVGKYDKAIELLEKALQGATNEGYQNDINTIKLQLSFVLQMVGKTAQSKEILKGLLQELKADSPFSLICQNNLNAFVDFSKYNTNFNLLLRELNVEKLNTFNLQTFTHEQWSNIQRNVLFLRLFNNVKIHSQESLLSRTFDKYSKLVDNVTLESYKTQAKKLYHHTTKTILSGTDGSTIGILLLTIQLLIIEKEWENAIRIGELFLNESWKSSFEKFNDSQAIVCYILFELYKIKGRNNSKSVLLKKLGSVRVQLSGKIQENIPFWKHVGFELLSMGNAKESKALLREISNFSKGDADVLVDRVVSSDSLDIAQGIDLVRDIDIDKLIQLGVKPLESSAKRSKNTAVSKVQKRKVLELKKKRKIKRLEKFLQGRDTSKLPDPERWLPLRDRSTYRPKKKQQGAKQTQGGAMNKKSEQALDISKKGKPTVNKKPKNKKKGRK
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (PubMed:7925282, PubMed:10921896).  The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER (PubMed:10921896, PubMed:7925282).  The SRP complex targets the ribosome-nascent chain complex to the SRP receptor (SR), which is anchored in the ER, where SR compaction and GTPase rearrangement drive cotranslational protein translocation into the ER (By similarity).  Binds signal recognition particle RNA (7SL RNA) in presence of SRP68 (By similarity).  Can bind 7SL RNA with low affinity (By similarity).  The SRP complex possibly participates in the elongation arrest function (PubMed:10921896).
What are the official names of this protein?
Signal recognition particle subunit SRP72, Signal recognition particle 72 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SRP72 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane. Nucleus, nucleolus. Note=Transiently localizes to the nucleolus during biogenesis of the SRP. The SRP-RNC complex is bound to the endoplasmic reticulum membrane due to the interaction of the SRP with the membrane SRP-receptor (SRP101-SRP102).
Protein: PACN1_BOVIN
Sequence: MSGSYDEASLAPEETTDSFWEVGNYKRTVKRIDDGHRLCNDLMSCVQERAKIEKAYAQQLTDWAKRWRQLLEKGPQYGSLERAWGAIMTEADKVSELHQEMKNSLLNEDLEKVKNWQKDAYHKQIMGGFKETKEAEDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAVTREMNSKTEQSVTPEQQKKLQDKVDKCKQDVQKTQEKYEKVLDDVGKTTPQYMEGMEQVFEQCQQFEEKRLVFLKEVLLDIKRHLNLAESSSYVQVYRELEQAIRGADAQDDLRWFRSTSGPGMPMNWPQFEEWNPDLPHTAAKKEKQPKKAEGAALTNAAGVVESTSQAGDRGSVSSYDRGQTYATEWSDDESGNPFGGSEANGGSNPFDEDAKGVRVRALYDYDGQEQDELSFKAGDELTKLGEEDEQGWCRGRLDSGQLGLYPANYVEVV
What is the function of this protein?
Binds to membranes via its F-BAR domain and mediates membrane tubulation.  Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization.  Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes.  Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex.  Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length.  Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission.  Required for normal excitatory and inhibitory synaptic transmission (By similarity).
What are the official names of this protein?
Protein kinase C and casein kinase substrate in neurons protein 1.
What is the protein family that this protein belongs to?
Belongs to the PACSIN family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection. Synapse, synaptosome. Cell projection, ruffle membrane. Membrane; Peripheral membrane protein. Cytoplasmic vesicle membrane; Peripheral membrane protein. Synapse. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Colocalizes with MAPT in axons. In primary neuronal cultures, present at a high level in presynaptic nerve terminals and in the cell body. Colocalizes with DNM1 at vesicular structures in the cell body and neurites. Associates with membranes via its F-BAR domain (By similarity).
Protein: LECM1_PHIOL
Sequence: MGRFIFVSLGLLVLAFSLSGIGADQHCPSGWFSHNVSCYKLINDWKTWDEAQRFCMDEQENGQLASINDVGESVKLSDEISKTWSIIDVWIGLRLSKRKSIWEWIDGSNVTQTRWEEGEPNNFLKKEFCVVLTSRSRYLKWNDKDCNRRHRFLCKF
What is the function of this protein?
Mannose-binding lectin which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids.  May be a calcium-dependent lectin (By similarity).
What are the official names of this protein?
C-type lectin lectoxin-Phi1, CTL.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1282_METMP
Sequence: MKLIGITGMPGSGKSAITKLAEKYKIVVVSMGDVVRYETLKQGMPLNPENVGNTAVKLREIYGKEAIAVPCLNYVNEKYNNEDFVIIEGIRSIYEVNYIKKHAELDIIAIHSSPKTRFERLSGRNREDDSNDWNTFVERDERELNFSIGRVISLADYMVVNEGNYMDFVNDLENTFKKIINVN
What are the official names of this protein?
UPF0200 protein MMP1282.
What is the protein family that this protein belongs to?
Belongs to the UPF0200 family.
Protein: P2SAF_ARATH
Sequence: MASLQLCDGYLLFKPSVSPRFLSQRISHRLIPKASSSPPPSPSPSSSSSSLSFSRRELLYQSAAVSLSLSSIVGPARADEQLSEWERVFLPIDPGVVLLDIAFVPDEPSRGFLLGTRQTLLETKDGGSTWNPRSIPSAEEEDFNYRFNSISFKGKEGWIIGKPAILLYTADAGENWDRIPLSSQLPGDMVFIKATEDKSAEMVTDEGAIYVTSNRGYNWKAAIQETVSATLNRTVSSGISGASYYTGTFSAVNRSPDGRYVAVSSRGNFFLTWEPGQPYWQPHNRAVARRIQNMGWRADGGLWLLVRGGGLYLSKGTGITEEFEEVPVQSRGFGILDVGYRSEEEAWAAGGSGILLRTRNGGKSWNRDKAADNIAANLYAVKFVDDKKGFVLGNDGVLLRYVG
What is the function of this protein?
Essential for photosystem II (PSII) biogenesis; required for assembly of an early intermediate in PSII assembly that includes D2 (psbD) and cytochrome b559.  Has been suggested (PubMed:11826309) to be required for chlorophyll a binding.
What are the official names of this protein?
Photosystem II stability/assembly factor HCF136, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the Ycf48 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen. Note=Restricted to the stromal lamellae (PubMed:9736608). Translocation into the thylakoid lumen occurs via the Tat pathway (Probable) (PubMed:10664464).
Protein: KEFB_SALCH
Sequence: MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSHRLNGPEENDEKPWVEDDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRILRELIPEHSDMVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL36_RALSO
Sequence: MKVLASVKRICRNCKIIKRKGVVRVICSSDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PPAX_LISMH
Sequence: MTGKITTLLFDLDGTLINTNELIIKTFQVTLQEFLPDRVFTREDILPFIGPSLMETFREINPAHADEMRAFYREYNLKHHDDLILEYDGVYEAIRALYEEDYKLGIVSTKMYDTIMRGLKVTGLDKFFQVVIGLDQVSNAKPDPEGIEMALSLLNATKEEAIMIGDNYHDIEAGKNAETLTAGVAWAIKGPEHLAQFQPDFMLEKMSDLLAIVRDEE
What is the function of this protein?
Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK/P.  Might play a role in controlling the intracellular pyrophosphate pool.
What are the official names of this protein?
Pyrophosphatase PpaX.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PpaX family.
Protein: LOX11_SOLTU
Sequence: MIGQITSGLFGGHDDSKKVKGTVVMMNKNVLDFTDLAGSLTGKIFDVLGQKVSFQLISSVQGDPTNGLQGKHSNPAYLENSLFTLTPLTAGSETAFGVTFDWNEEFGVPGAFIIKNMHINEFFLKSLTLEDVPNHGKVHFVCNSWVYPSLNYKSDRIFFANQPYLPSETPELLRKYRENELLTLRGDGTGKREAWDRIYDYDIYNDLGNPDQGKENVRTTLGGSAEYPYPRRGRTGRPPTRTDPKSESRIPLILSLDIYVPRDERFGHLKMSDFLTYALKSIVQFILPELHALFDGTPNEFDSFEDVLRLYEGGIKLPQGPLFKALTAAIPLEMIRELLRTDGEGILRFPTPLVIKDSKTAWRTDEEFAREMLAGVNPVIISRLQEFPPKSKLDPEAYGNQNSTITAEHIEDKLDGLTVDEAMNNNKLFILNHHDVIIPYLRRINTTITKAYASRTLLFLQDNGSLKPLAIELSFPHPDGDQFGVTSKVYTPSDQGVESSIWQLAKAYVAVNDVGVHQLISHWLNTHAVIEPFVIATNRQLSVLHPIHKLLYPHFRDTMNINASARQLLVNAGGVLESTVFQSKFAMEMSAVVYKDWVFPDQALPADLVKRGVAVEDSSSPHGVRLLIEDYPYAVDGLEIWSAIKSWVTDYCSFYYGSDEEILKDNELQAWWKELREVGHGDKKNEPWWPEMETPQELIDSCTTIIWIASALHAAVNFGQYPYAGYLPNRPTVSRRFMPEPGTPEYEELKRNPDKAFLKTITAQLQTLLGVSLVEILSRHTTDEIYLGQRESPEWTKDKEPLAAFDRFGKKLTDIEKQIIQRNGDNILTNRSGPVNAPYTLLFPTSEGGLTGKGIPNSVSI
What is the function of this protein?
Plant lipoxygenases may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure.
What are the official names of this protein?
Linoleate 9S-lipoxygenase 1, Lipoxygenase 1, StLOX1.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
What are the subcellular locations of this protein?
Cytoplasm.