PharMolix/UniProtQA huggingface dataset:
Protein: SYFB_AYWBP
Sequence: MQGTPTMKIIENILKNHLLQPLSQNIFVLTNNYITEVQKFSPLSKNTNLVVGQILNFQKIQDSQKLNLVEVNIGIKVVKIVCGASNLQNGKKVIVASEGSFLEGINSTLKNKKIYGVFSEGMLCALEELGISNKFLTPQEQEGIYLFDDPNDQIALGSNALIPLGMDGFILELGITPNRGDLLSHIGFAKDLQAVLASQNSNKKKEKKTINYKTKNSKDQTNRKTTPKLNPDFFAKLPQSPLKVQIESDSCYEYNVCILENITIKPSPLWLRNTLLQSGINPINNVVDITNLILIEYGIPLHAFDSGTIQKIKVRKAFPQETITTLNQNDFVLDENDLVITDGKKAIALAGIVGLLESSIKPTTTKIILEAAYFSPQTIAQTCQKLKNKTESSLRFERGIDQNLIPLAFQKACQLLVTLANAKITYQPTITKQKIRTNPTISLDLDFITRKIGFSLCPTQIKNWLLNLDYQIHTPKNLTLQNKNEQLNLQAPLRRYDVKIKEDVISDLTRFYGCHKLPPQTIQIPTQGKLTLKQKNIRELRKLLVNLGFYETITYSLISSEMFEAFAPQKPFIKIMNPLSQDKMILRQSLLSSLVEILSYQHKRQTFDTAFFEIGKAYFPNQEKLSLAFVLSGNFLNTLWHKQDVSSSFFVTKGILEKISSFLGITLTYQKTQKHSNFHPGMQANLLFNNQIIGVIGKTHPQLNAKHHLKESFLCELFLSDEILNTTKTLTFRPIPKFPTVIRDLSFLVDTKYSFYQIEQIIKQTTPFDLIKCELFDVYQTPTTKEKQSFALRFFFNNLDKNLEKQDVEHCMKKITYNLIKHFRIEIR
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMA_VIBVY
Sequence: MPWIQIKLNATNENAELIGDMLMEETGALSVTFLDAHDTPVFEPLPGETRLWGDTDVLALYDAEADTQLIMSQIKASNMLAEGFAYKIEQLEDKDWEREWMDNFHPMKFGQRLWICPSWRDIPDPTAVNVMLDPGLAFGTGTHPTTALCLEWLEGLDLSGKTVIDFGCGSGILAIAAIKLGAEKVIGIDIDPQALLASKDNAQRNGVADQLDVYLPQDQPEGLLADVVVANILAAPLRELSSIIKGLVKPNGQLAMSGVLDTQAEDVANYYRDELHIDPIVEQSEWCRISGRKQG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: USPE_YERPE
Sequence: MGKYQNILVAIDPNQDDQPALRRAVYLVQRNGGTIKAFLAIYDLSYDMTTLLSPDERTAMRKGVISQRSAWISEQCRFYIDSGIPIDIKVVWHNRPYEAIIQEVLKAKHDLLLKMAHQHDRLESIIFTPTDWHLLRKCPCPVWMVKDQPWPEEGTALVAVNLSSEDPLHDPLNLRLVKETLELAEHVNQTPVHLISAYPVTPINIAIELPDFDPSVYNDAIRGQHLVAMKALRQQFGIDEKFTHVEKGLPEEVIPDLAEHLNAGVVVLGTLGRTGLSAAFIGNTTEHVIDNLKCDLLAIKPEGFTCPIEGNEDQEDAE
What is the function of this protein?
Required for resistance to DNA-damaging agents.
What are the official names of this protein?
Universal stress protein E.
What is the protein family that this protein belongs to?
Belongs to the universal stress protein A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKN1_MOUSE
Sequence: MAGDAVQSEPRSWSLLEQLGLAGADLAAPGVQQQLELERERLKREIRKELKLKEGAENLRRATTDLGRSLAPVELLLRGSARRLDLLHQQLQELHAHVVLPDPAAGSDATQSLAEGSPICSSTNLSRVAGLEKQLAIELKVKQGAENMIQTYSNGSSKDRKLLLTAQQMLQDSKTKIDIIRMQLRRALQALQAGELESQAAPDEAQGDPELGAVELRIEELRHHFRVEHAVAEGAKNVLRLLSGAKAPDRKAVSEAQEKLTESNQKLGLLRESLERRLGELPADHPKGRLLREELTAASSSAFSAILPGPFPATHYSTLSKPAPLTGTLEVRVVGCKNLPETIPWSPPPSVGASGTPESRTPFLSRPARGLYSRSGSLSGRSSLRGEAENATEVSTVLKLDNTVVGQTAWKPCGPNAWDQSFTLELERARELELAVFWRDQRGLCALKFLKLEDFLDNERHEVQLDMEPQGCLVAEVTFRNPIIERIPRLQRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPSAVATGTFSPNASPGAEIRHTGDISMEKLNLGADSDSSSQKSPPGLPSTSCSLSSPTHESTTSPELPSETQETPGPGLCSPLRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRSSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTRAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAVFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSTERDAEDVKKQPFFRSLGWDVLLARRLPPPFVPTLSGRTDVSNFDEEFTGEAPTLSPPRDARPLTAAEQAAFRDFDFVAGGY
What is the function of this protein?
PKC-related serine/threonine-protein kinase involved in various processes such as regulation of the intermediate filaments of the actin cytoskeleton, cell migration, tumor cell invasion and transcription regulation.  Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14.  Regulates the cytoskeletal network by phosphorylating proteins such as VIM and neurofilament proteins NEFH, NEFL and NEFM, leading to inhibit their polymerization.  Phosphorylates 'Ser-575', 'Ser-637' and 'Ser-669' of MAPT/Tau, lowering its ability to bind to microtubules, resulting in disruption of tubulin assembly.  Acts as a key coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of 'Thr-11' of histone H3 (H3T11ph), a specific tag for epigenetic transcriptional activation that promotes demethylation of histone H3 'Lys-9' (H3K9me) by KDM4C/JMJD2C.  Phosphorylates HDAC5, HDAC7 and HDAC9, leading to impair their import in the nucleus.  Phosphorylates 'Thr-38' of PPP1R14A, 'Ser-159', 'Ser-163' and 'Ser-170' of MARCKS, and GFAP.  Able to phosphorylate RPS6 in vitro.
What are the official names of this protein?
Serine/threonine-protein kinase N1, Protein kinase C-like 1, Protein kinase C-like PKN, Protein-kinase C-related kinase 1, Serine-threonine protein kinase N.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Endosome. Cell membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Note=Associates with chromatin in a ligand-dependent manner. Localization to endosomes is mediated via its interaction with RHOB. Association to the cell membrane is dependent on Ser-377 phosphorylation. Accumulates during telophase at the cleavage furrow and finally concentrates around the midbody in cytokinesis.
Protein: MEND_SYNP6
Sequence: MGQAAAITMPIDPRNLNTLWSSVLAESFVRLGLQTVVICPGSRSAPLAIAFAEHPEIDAIPILDERSAGFFALGRAKASHRPVALICSSGTAGANFYPAVIEAKESGVPLLVITADRPPELRQCHAGQAIDQLRLFGSYALWEAELALPVLDLGLLRYLRQTAQQAWQQALRGGPVHLNQPLREPLAPIADPATQTWLAQQWPGENFFAELLTAVPTPQIQQPLPPLPSQGLITVGPIAPEDPAAFVQAIAQLSAHLGWPVLSDAVTPLRQFADHCPRLISSYDLILRQPHWRASLQPEAVLQIGELPTSKELRLWLTEQTCPRWIVSPRPENFDPLHGSSHHLPVTVEAIAIPATIAPASDYSRQWQQAETAVQAAIAQHLAQVPDLTEPGIARLLSQHLPAQTPIFVANSTPIRDLEWFWLANDQRRSLYCSRGANGIDGTLSTAIGIAHQNRPSVLITGDLSLLHDSNGFLQRSQLQGHLTVVLIDNSGGGIFELLPIRDCGPSFEPFVATPQTVDFAALCQAYGVDYQAIATEAELIKAIQTLPTSGIRVLHLFTDRRQNAAWRRALFAELAAIPSQS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: SLYA_ECO27
Sequence: MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: SYGA_BRUAB
Sequence: MHPTRSFQGLILTLHNYWAEHGCAILQPYDMEVGAGTFHPATTLRSLGPKPWKAAYVQPSRRPKDGRYGENPNRLQHYYQYQVLIKPSPPNLQDLYLGSLKAIGLDPTLHDVRFVEDDWESPTLGAWGLGWECWCDGMEVSQFTYFQQVCGIECSPVAGELTYGLERLAMYVQGVDNVYDLNFNGLEGDEKVTYGDVFLQAEQEYSRYNFEMANTETLHQHFIDAERECEAILKAGSTGENSLHKCVFPAYDQCIKASHVFNLMDARGVISVTERQGYILRVRNLARQCGEAFLLTDAGGFNFKREGE
What are the official names of this protein?
Glycine--tRNA ligase alpha subunit, Glycyl-tRNA synthetase alpha subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSMD8_BOVIN
Sequence: MAATAVNGVAGTSSSGSAAASGAILQAAAGMYEQLKGEWNRKSPNLSKCGEELGRLKLVLLELNFLPTTGTKLTKQQLILARDIQEIGAQWSILRKDIPSFERYMAQLKCYYFDYKEQLPESAYMHQLLGLNLLFLLSQNRVAEFHTELERLPAKDIQTNVYIKHPVSLEQYLMEGSYNKVFLAKGNIPAESYTFFIDILLDTIRDEIAGCIEKAYEKILFTEATRILFFNTPKKMTDYAKKRGWVLGINNYYSFASQQQKPEDTTIPSTELAKQVIEYARQLEMIV
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 8, 26S proteasome regulatory subunit RPN12.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S14 family.
Protein: NU1M_TRIVU
Sequence: MFIINLLLYIIPILLAVAFLTLVERKALGYMQFRKGPNIVGPYGLLQPIADAVKLFTKEPLRPLTSSISMFIIAPILALTLAFTIWTPLPMPHSLIDLNLGLLFILALSGLSVYSILWSGWASNTKYALMGALRAVAQTISYEVTLAIILLSIMLINGSFTLKNLIITQENMWLIMTTWPLTMMWYISTLAETNRAPFDLTEGESELVSGFNVEYAAGPFAMFFLAEYANIMAMNAMTTILFLGSSINHNFTHLNTLSFVIKTALLTFMFLWVRASYPRFRYDQLMYLLWKNFLPLTLAFCLWFISIPVALSCIPPQI
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MURA_AROAE
Sequence: MDKLLIEGGVRLAGEAAISGAKNAALPILCAALLTREPVTLTNVPQLNDIDTLLNLLGQMGVKVSRDNAAVTLDASAIDNPVAPYEMVKTMRASILVLGPLVARCGEARVSLPGGCAIGARPVDQHIKGLQAMGAQVTVEHGYVHAVVSRLAGARLFTDMVTVTGTENLMMAACLADGETVIENAAREPEVVDLANCLVAMGARISGAGTDVIRIRGVDRLNGATHRIMPDRIETGTYLCAAAATGGEIRLTRTSTAYLDAVVDKLMDAGCDVVTERDAIRLKAPARLTSVNIRTSPYPAFPTDMQAQFMAINAVASGAAMIRETIFENRFMHAVELQRLGADIRIDGNTAVVQGVERLQGATVMATDLRASASLVIAGLVAEGETVIERIYHLDRGYERLEEKLAALGAHVRRIA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSV2_YEAST
Sequence: MDVRRPIREAVNNRRKPKFLSVSFNQDDSCFSVALENGFRIFNTDPLTSKLSKTFKESATNQSRGTGIGYTRMLYRTNYIALVGGGKRPRHALNKLIIWDDLLQKETITLKFMSSIKDVFLSRIHIVVVLENTIEIFQFQTNPQRICPILDIPPNGSVDYVVCSSKHLQSQASQSQSKILEIIAFPSNKCVGQIQVADLSQIKYNSQNPKESALLPTSIIKAHKNPIKLVRLNRQGTMVATCSVQGTLIRIFSTHNGTLIKEFRRGVDKADIYEMSFSPNGSKLAVLSNKQTLHIFQIFETTNTETNTPDHSRANGSSHPLKNYIPKGLWRPKYLDSVWSICNAHLKNPIFDAHRNDNSGDVTHDNEFYKDRCRIGWCQDSNNREQDDSLVLVWQNSGIWEKFVILEKEQQDSSKTHYSLNESLRNEDTKSAGEPTRWELVRESWREL
What is the function of this protein?
Involved in piecemeal microautophagy of the nucleus (micronucleophagy).
What are the official names of this protein?
SVP1-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the WD repeat PROPPIN family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein. Prevacuolar compartment membrane; Peripheral membrane protein. Note=Recruitment to endosomes depends on binding to phosphatidylinositol 3-phosphate.
Protein: PYRF_CUPTR
Sequence: MTFTEQLAAAWQRNDSLLCVGLDPDPHKLPLSLTGAGGAIFSFCREIVDATADLVCAFKPQIAYFHSQRAEDQLEQLIHYIHDAHPGIPVILDAKRGDIGSTAEHYALEAFERYKADAVTVSPYMGFDSMQPYLAYPERGVIVLCRTSNPGGSDVQFLQVDGKPLYQLVAEAARERWNTTGQMGLVVGATFPNEIARVRQIVGDMPLLIPGIGAQGGDIEATVKAGRTADGTGMMINSSRAILYASREKDFAAAARNVALQTRETINRYRHG
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 2 subfamily.
Protein: CBIM1_METLZ
Sequence: MHFMDGFLPIGWCVFWAVLAAPFLIYGMWKITKMINNDRHVLPLMAVCGAFIFVVSLVDIPSPTGSCSHPTGTGLSASFFGPAVTSVLGLIILVFQALLLGHGGFTTLGATAFSMAVMGPLAAWLVFKGLRKTGRVPLGPAVFCAAVVANCVTYLITSLQIALAYPVEGSVLTAFLAAAAVFAVVQIPISIIEGIISGLVATYIARIKPEILQKLGVISGEEVKKVLSEQA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Putative cobalt transport protein CbiM 1, Energy-coupling factor transporter probable substrate-capture protein CbiM 1, ECF transporter S component CbiM 1.
What is the protein family that this protein belongs to?
Belongs to the CbiM family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HUTH_MOUSE
Sequence: MPRYTVHVRGEWLAVPCQDGKLTVGWLGREAVRRYMKNKPDNGGFTSVDEVQFLVHRCKGLGLLDNEDELEVALEDNEFVEVVIEGDVMSPDFIPSQPEGVFLYSKYREPEKYIALDGDSLSTEDLVNLGKGRYKIKLTSIAEKKVQQSREVIDSIIKERTVVYGITTGFGKFARTVIPANKLQELQVNLVRSHSSGVGKPLSPERCRMLLALRINVLAKGYSGISLETLKQVIEAFNASCLSYVPEKGTVGASGDLAPLSHLALGLIGEGKMWSPKSGWADAKYVLEAHGLKPIVLKPKEGLALINGTQMITSLGCEALERASAIARQADIVAALTLEVLKGTTKAFDTDIHAVRPHRGQIEVAFRFRSLLDSDHHPSEIAESHRFCDRVQDAYTLRCCPQVHGVVNDTIAFVKDIITTELNSATDNPMVFASRGETISGGNFHGEYPAKALDYLAIGVHELAAISERRIERLCNPSLSELPAFLVAEGGLNSGFMIAHCTAAALVSESKALCHPSSVDSLSTSAATEDHVSMGGWAARKALRVVEHVEQVLAIELLAACQGIEFLRPLKTTTPLEKVYDLVRSVVRPWIKDRFMAPDIEAAHRLLLDQKVWEVAAPYIEKYRMEHIPESRPLSPTAFSLESLRKNSATIPESDDL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
Protein: EAMB_SALPA
Sequence: MTPMLLSAFWTYTLITALTPGPNNILALSAATAHGFRQSIRVLAGMSLGFLVVMLLCAGIAFSLAVIDPAIIHLLSWVGAAYILWLAWKIATSPAADEKVRPKPVGFWVSFGLQFVNVKIILYGITALSTFVLPQTQALNWVIGVSILLALIGTFGNVCWALAGHLFQRAFRHYGRQLNIILALLLVYCAVRIFY
What is the function of this protein?
Exporter of O-acetylserine (OAS) and cysteine.
What are the official names of this protein?
Cysteine/O-acetylserine efflux protein.
What is the protein family that this protein belongs to?
Belongs to the Rht family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENOPH_LODEL
Sequence: MTIDTVILDIEGTICPISFVKSVLFPYFVKQLPTTLNTIQFPLNLNINDTNSNQASIVQTLSKLPLSVTTSSESTYNYLKGLVDNDVKDPVLKALQGLIWKQGYESGEIKSPVYPDSIDFIEKFPKREANCKIYIYSSGSINAQKLLFSHVDNGTGIAMDLNPQLSGYFDITTAGFKQEASSYTKIIDQIDKKDNEKSVLFLSDYINEVNAAIESGMNSYVVIREGNTPIPDKELASHKIIYSLSELNL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CY550_LIMMA
Sequence: LTEELRTFPINAQGDTAVLSLKEIKKGQQVFNAACAQCHALGVTRTNPDVNLSPEALALATPPRDNIAALVDYIKNPTTYDGFVEISELHPSLKSSDIFPKMRNISEDDLYNVAGYILLQPKVRGEQWG
What is the function of this protein?
Low-potential cytochrome c that plays a role in the oxygen-evolving complex of photosystem II.
What are the official names of this protein?
Cytochrome c-550, Cytochrome c-549, Cytochrome c549, Cytochrome c550, Low-potential cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PsbV subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Lumenal side. Note=Associated with photosystem II at the lumenal side of the thylakoid membrane.
Protein: UPP_BLOFL
Sequence: MKIIEIRHPLVQHKLGLMRINDISTKRFRELSSELSSLLTYVATDDLEIETVIIKGWNGLVKIARIKGKKITVVPILRAGLGMMDGVLEHVPSARISMIGVYRDEITLEPIPYFHKLVSRINERMAMVLDPMLATGGTVIATVDLLKKAGCHNIKILSLVAAPEGIAALEKKHPDVELYLASIDQKLNKYGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: PAMT_CAPCH
Sequence: MANITNEFMGHDMLAPFTAGWQSDMEPLVIEKSEGSYVYDINGKKYLDTLSGLWCATLGGSETRLVEAANKQLNTLPFYHSFWNRTTKPSLDLAKELLNMFTANKMAKVFFTNSGSEANDTQVKLVWYYNNALGRPQKKKIIARAKAYHGSTYISAGLSGLPPMHQKFDLPPPFVLHTECPHYWAYHLPGETEEEFSTRLANNLESLILKEGPETVAAFIAEPVLGAAGVILPPATYFDKVQTILRKYDILFIADEVVCGFGRLGTMFGGDKYNIKPDLVSVAKALSSGYMPIAAVLVSQKISSVILSESNKIGAFCHGFTYSGHPVACAVALEALKIYKERNITEVVNKISQKFQEGLKAFADSPIIGEIRGTGLALSTEFVDNKSPNDPFPYEWAVGTYFGAQCAKYGMLVSSTGDHVNMAPPFMLSLEELDELIRIYGKALKDTEKRVEELKSQKK
What is the function of this protein?
Participates in the biosynthesis of capsaicinoids in pungent cultivars of Capsicum chinense (Ref. 2, PubMed:31323150).  Capsaicinoids, the alkaloids responsible for the heat or pungency of chili pepper, are synthesized from phenylpropanoid intermediates in the placental tissue of chili peper fruit (Probable).  Can transfer an amine from vanillylamine to pyruvate forming vanillin and L-alanine (PubMed:24712445).  Can use pyruvate or oxaloacetate, but not 2-oxoglutarate as amino group acceptors (PubMed:24712445).  Is able to convert (S)-1-phenylethylamine into acetophenone in vitro (PubMed:24712445).
What are the official names of this protein?
Vanillin aminotransferase, Putative aminotransferase, pAMT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: SYFA_XANC8
Sequence: MSEIQSLTAQALADVAAAHTPDQLETLRVALLGKNGSITAQLKQLGTLPADQRKAAGEAINLARDALTTALSERKQVLETAALDARLEGERIDVTLPGRRGERGGLHPVTRTLERIVEIFARLGYELSDGPEIEDDWHNFEALNFPPHHPARAMHDTFYFGDGRLLRTHTSGVQVRYMDTAVATKSGPPLRMIAAGKVYRSDSDQTHSPMFHQVEGLLVDEHSNFADLKGTLSEFVRAFFERDFEMRFRPSYFPFVEPGAEVDIAWQQPDGSTRWLEVLGCGMVHPNVLRSVGIDPERYTGFAFGLGVERFAMLRYGVNDLRAFFENDVRFLRQFA
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_LEGPH
Sequence: MMEVTAKLKGAPLSAQKGRLVADMIRNMNVSGALDVLKFTPKKGAKLMLKLLESAIANAENNNGADIDDLKVGMVCVDEATTLKRISPRAKGRANRICKRTCHITIKVSDEE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: Y769_MYCTO
Sequence: MFDSKVAIVTGAAQGIGQAYAQALAREGASVVVADINADGAAAVAKQIVADGGTAIHVPVDVSDEDSAKAMVDRAVGAFGGIDYLVNNAAIYGGMKLDLLLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKRGGGAIVNQSSTAAWLYSNFYGLAKVGVNGLTQQLARELGGMKIRINAIAPGPIDTEATRTVTPAELVKNMVQTIPLSRMGTPEDLVGMCLFLLSDSASWITGQIFNVDGGQIIRS
What are the official names of this protein?
Uncharacterized oxidoreductase MT0793.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SSRP_SPHAL
Sequence: MVRPQSAAEFDKKKVVAENRRARFDYAIEQVFEAGIALQGTEVKSLRFGEGTIAESYAEVNGGEVWLINANIPEFSHGNRFNHEPKRPRKLLLNWREINKLHAGVARQGMTLVPLSVYFNSRGRAKVELALAKGKKAHDKRESIKERDWKRDKQRLLKDRG
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LEU1_ECOLI
Sequence: MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITEYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RS3_PSET1
Sequence: MGQKVHPTGIRLGISKPWVSTWYASSKDFSAQLFGDHKVRTFLTKELKTASVSKIVIERPAKSIRVTIHTARPGVVIGKKGEDVEKLRQAVTKIAGVPAQINISEVRKPELDAQLVADGIASQLERRVMFRRAMKRSVQNAMRIGSKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYATSEALTTYGIIGVKVWIFKGEVIGGLPLVQEQEKPAKRAPKKAKKSAK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RL37_THEAC
Sequence: MSNGTAVMGKINNKKTHIRCRRCGHHTYNVRTKRCSHCGFPAPRIRSYRWAKAK
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L37e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL37 family.