PharMolix/UniProtQA huggingface dataset:
Protein: GLMU_SHIFL
Sequence: MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGTKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AVR10_PHYIT
Sequence: MRLSFIIFAISLLAGGSGAAEALHPASDVLTLRGTNQGASTGKRSLRYDNNAERAGEEDDEERAFPGAEELSRLANLAHTSKADSLGTSLKNFFKQLDKANVNPSNIHKYGFSGEEFDQLRKRFGTWYRHYKDIE
What is the function of this protein?
Secreted effector that acts as an elicitor of hypersensitive response (HR) specifically on plants carrying defense protein R10 (PubMed:11768540).  Enhances P. infestans colonization of Nicotiana benthamiana leaves (PubMed:30329083).
What are the official names of this protein?
RxLR effector protein Avr10, Avirulence protein 10.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Host cytoplasm.
Protein: MU121_SCHPO
Sequence: MKGFVVISRFILTLFILITPGLAGVVNYAENSEWNVPKYGNVLDSNCQGQKPVTFFGSVTEHVSNSWWIKLYDYMMTFISGEKLCMQNVAYEFEDISLCMDVVGSKCIPTLQSTDIEKVVNSTSAYLENSESDLTLGCFQIQRFQEESTLYIRALKSSEPVSCDTVRCIHFNHIPYV
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 121 protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus.
Protein: DTX27_ARATH
Sequence: MRGGDGEEGSESRVALLKSPHTAEEDGEGLKDRILVETKKLWQIVGPAIFSRVTTYSMLVITQAFAGHLGDLELAAISIVNNVTVGFNFGLLLGMASALETLCGQAFGAKKYHMLGVYMQRSWIVLFFCCVLLLPTYIFTTPVLKFLGQPDDIAELSGVVAIWVIPLHFAFTLSFPLQRFLQCQLKNRVTAYAAAVALVVHILVCWLFVDGLKLGVVGTVATISISWWVNVLILLVYSTCGGCPLTWTGLSSEALTGLWEFLKLSASSGVMLCLENWYYRILIIMTGNLQNARIAVDSLSICMAINGWEMMIPLAFFAGTGVRVANELGAGNGKGARFATIVSVTQSLIIGLFFWVLIMLLHNQIAWIFSSSVAVLDAVNKLSLLLAFTVLLNSVQPVLSGVAVGSGWQSYVAYINLGCYYCIGVPLGFLMGWGFKLGVMGIWGGMIFGGTAVQTMILSFITMRCDWEKEAQKASARINKWSNTIK
What are the official names of this protein?
Protein DETOXIFICATION 27, AtDTX27, Multidrug and toxic compound extrusion protein 27, MATE protein 27.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NU5M_LYCSM
Sequence: MNLITPTIILTIMLSLMMSIMQPHNNTKNNLMVLFLISLIPINPLLNNNELTLTLTPLIISPTENINISITLDTASLLFTPIALFITWSITEFSLWYMATDPNINKFIKYLLTFLITMLVIITANNMYQLFIGWEGVGIMSFLLIGWWHGRQDANTAALQAIIYNRIGDIGLIMTTAWMMTTSSINMQELMIQHEVVNIIPLLGLVAAATGKSAQFSLHPWLPSAMEGPTPVSALLHSSTMVVAGVFLLIRLHPILHNNKIMLTCCLILGATTTMFAAAAATTYFDIKKIIALSTTSQLGLMMTMIGLNQPTLAFLHMITHSFFKAMLFLCSGSYIHNLNNEQDIRMMGGLLKTLPMTSSFLTIANLSLMGMPFLSGFYSKDTIIETLANSYTNSWAIMITMIATILSACYSTQIMLFTIMEHPRTHHTTHKETKNITHPLARLMLTSILMGTMTKMSTLQTTTMVTMPKTIKLMALISTIIGVLLSKDLTHMTHHMKPKKPNKQNMFFNQLAFFNIPHRTITINTLKISQQTSTELMDLWTLEVWGPKGLSNTITNTIHLLTQQKNMIKNYMAIFTMTTMTVLLFIMSK
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y4222_CLOB8
Sequence: MSGHSKWHNIQAKKGKTDAKRGKIFTKIGKEIVMAVKNGGANQDINAKLRDVVAKAKAANMPNDTISKAIKKASGELSSVNYENIVYEGYGPSGVAVIVETLTDNKNRSAGNVRSAFTKGGGNMGTSGCVSFMFQEKGEIVIEKEDKDEDELMMIALDAGAEDFASEEEVFVVTTAPEEFGTVREALEAQGIEFLEASVKMIPDTYTAIDEADAKKFQKMLDLLDDDDDVQEVYHNAEFPEGWDE
What are the official names of this protein?
Probable transcriptional regulatory protein Cbei_4222.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSRA_SHIFL
Sequence: MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAAMLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: RN207_DANRE
Sequence: MSGEIFYSVDNLYDLDSANCHPLVCHLCQEQYEHPCLLDCYHTFCASCLRGRVADSRLTCPVCGHQSVVKGINALPPEDRLLKFLVDSSADSEETVQCANCDLECKKQDVDAMYYCNTCCQPLCRDCRETTHKAKMFSRHEIVSLAKRTKEAHKKCALHEEFYIMFSTEKKSMLCINCFRDMQVESRAHCIDIETAYIQGCEKLDQAVLAVKELQMSAREAIILLKAMIGEVRANVDEEESAICTLFSNMQEKLAERKKILLKAARSQHEEKERTFKEQLSHLAALLPTLQVHLVTCSAFLSSANKFEFLDMGYQLMERLKKIVKLPHRLRPTQSSKINTEYRSEFARCLEPLLLLGQRRSMSTTGSVALALGNASGLMQSSLSVQCHSPAMSDMSLCSSVVRRPTSHRYISTKVLLAKGGETPFMEHCCNYENSYRTLQTEIQKLKDQVQEIHRDLTKHHSLTKPDSMSEILEKSVQVDSQISSEYASVELMRAMFEEIWEETLQRVANEQEIYEAQLHDLLQLKQENSYLTTISRQIGPYIRSIAKVKERLEPRLKEPKELKDDRTEIMLKLYEDSTSTADTQPSNELSCNTEDNWTLNSLSEETNPKNKDYYRTNKQKNTTDSTNRKEIPM
What is the function of this protein?
Plays a role in cardiac repolarization possibly by stabilizing membrane expression of the potassium channel kcnh6a/zerg, or by assisting its synthesis, folding or export from the endoplasmic reticulum, in a heat shock protein-dependent manner.
What are the official names of this protein?
RING finger protein 207.
What are the subcellular locations of this protein?
Cytoplasm. Note=Probably located in the endoplasmic reticulum and/or possibly the cis-Golgi apparatus.
Protein: SCPB_LISMH
Sequence: MNREEQLGILESLLFAAGDAGLSTEQLTEVMEITHIEALNLLELLSERYNGSADRGLILLELAGTFQLATKKAHADYLRKLVEVPSNTVLSQASLETLAIIAYRQPVTRMEVDEVRGVQTDGPIRTLVAKGLVTDKGRVDGAGRAKLYVTTSEFLDAFGLNSLEDLPKLADPAAEEPDQNEMDLFFDRFNQSKEQEEE
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: GL_HCMVA
Sequence: MCRRPDCGFSFSPGPVVLLWCCLLLPIVSSVAVSVAPTAAEKVPAECPELTRRCLLGEVFQGDKYESWLRPLVNVTRRDGPLSQLIRYRPVTPEAANSVLLDDAFLDTLALLYNNPDQLRALLTLLSSDTAPRWMTVMRGYSECGDGSPAVYTCVDDLCRGYDLTRLSYGRSIFTEHVLGFELVPPSLFNVVVAIRNEATRTNRAVRLPVSTAAAPEGITLFYGLYNAVKEFCLRHQLDPPLLRHLDKYYAGLPPELKQTRVNLPAHSRYGPQAVDAR
What is the function of this protein?
The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell.  Acts as a functional inhibitor of gH and maintains gH in an inhibited form.  Upon binding to host integrins, gL dissociates from gH leading to activation of the viral fusion glycoproteins gB and gH (By similarity).  In human cytomegalovirus, forms two distincts complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope.  The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA.  The gH-gL-UL128-UL130-UL131A pentamer is essential for viral entry in epithelial, endothelial and myeloid cells via interaction with host NRP2 (By similarity).
What are the official names of this protein?
Envelope glycoprotein L, gL.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein L family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Extracellular side. Host cell membrane; Peripheral membrane protein; Extracellular side. Host Golgi apparatus, host trans- Golgi network. Note=gL associates with the extravirion surface through its binding to gH. During virion morphogenesis, this protein probably accumulates in the host trans-Golgi where secondary envelopment occurs.
Protein: YDCM_METLD
Sequence: MQSFLKLLLSYRIAKMNTTIETEVNYLDQSVESSLYRNGKVYTFRDTDGNDSNWYGAKLTPQKVVINDAREKNHTIDANGFELINAPLLKENLDFLDLNDVVKNYYPQCEDILKKATHASEVYAFDHNIRWKSANEQQTQITDGQQIQQPIYVMHGDYTISSVEDRIYALGKPLGDNDTLKKFLEPGAALIPHNVISKIFDEKKRFSIINVWRNID
What are the official names of this protein?
Uncharacterized protein in dcmA 3'region.
Protein: CLPS_DESVH
Sequence: MSNGPLAPGYDSDILVEDDVRLPRMYRVLLHNDDYTTMEFVVSILVEVFRKTAEQATAIMLAVHRDGVGECGVYTFEVAETKAAIVHARARREGYPLRCSTEEV
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: HMOX3_RAT
Sequence: MSSEVETAEAVDESEKNSMASEKENHSKIADFSDLLKEGTKEADDRAENTQFVKDFLKGNIKKELFKLATTALSYSAPEEEMDSLTKDMEYFFGENWEEKVKCSEAAQTYVDQIHYVGQNEPEHLVAHTYSTYMGGNLSGDQVLKKETQPVPFTREGTQFYLFEHVDNAKQFKLFYCARLNALDLNLKTKERIVEEATKAFEYNMQIFSELDQAGSIPVRETLKNGLSILDGKGGVCKCPFNAAQPDKGTLGGSNCPFQMSMALLRKPNLQLILVASMALVAGLLAWYYM
What is the function of this protein?
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin.  Biliverdin is subsequently converted to bilirubin by biliverdin reductase.  Heme oxygenase 3 could be implicated in some heme-dependent regulatory role in the cell.
What are the official names of this protein?
Putative heme oxygenase 3, HO-3.
What is the protein family that this protein belongs to?
Belongs to the heme oxygenase family.
Protein: MURC_RALSO
Sequence: MKHIVKNIHFVGIGGAGMSGIAEVLLNLGYRVTGSDLGQSAATQRLTALGATVMQGHAPEHVVGANAVVVSTAVRGDNPEVLAARAKRIPIVPRAVMLAELMRLKQGIAIAGTHGKTTTTSLVASVLAEGGLDPTFVIGGRLNSAGANARLGTGDFIVAEADESDASFLNLFPVIEVITNIDADHMDTYGHDFARLKQAFIEFTHRLPFYGIAVLCVDDPNVREILPFVSKPVVRYGFAEDAQVRAVNARAVDGRMEFTVIRQLNGHAEPPLSITLNLPGMHNVQNALAAIAIATELEVPDEAIVKALAEFNGVGRRFQRYGEVPTADGQGRFTLIDDYGHHPVEMAATLAAARGAFPGRRLVLAFQPHRFTRTRDCFEDFIKVLGTVDALLLAEVYAAGEPPIVAADGRALTRALRVAGKIEPVFVEQIEDMPQAILDAAQDNDVVITMGAGSIGQVPGQVVARQAEVRAANVVDLNGGAAA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WALR_STAA9
Sequence: MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins (By similarity).  Functions as a transcription regulator by direct binding to promoter regions (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein WalR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_CUPNH
Sequence: MIQTESRLEVADNTGAREVLCIKVLGGSKRRYASVGDIIKVTVKDAAPRGRVKKGDIYNAVVVRTAKGVRRADGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRTERFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: GL1D1_XENTR
Sequence: MKILFLACLRAHTGNSTTALRIKDHLEAAGHTCVLKDAAILESSEVETLISQEKFNAGLIIQLYKAGRFLMGNRIPFGAIFGGTDINEDVKNEEKCRVMGAVLEEARFVVAFTHKIKELAATKWPHAKHKIHIQPQGILTKPSKSFDYEAFLQNAGIRHKSGHLHLYVLICGLRRVKDPLYLAEMFAKWHEKEPNVYLAIIGPMVDPVFTKEVENKLEEIDGVYLIKEIPQSDLQAVIKRSFALVNSSLSEGMSAAILEAMDLEVPVLARDIPGNSAIIKHEDTGLLFSTPQEFVQLSKRLMTEPELKRRIVSNAKRYVNSNHSWELERDTYQTLILNLQVNGNI
What are the official names of this protein?
Glycosyltransferase 1 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SENP5_MACFA
Sequence: MKKQRKILWRKGIHLAFSEKWNTGFGGFKKFYFHQHLCILKAKLGRPITRNRQLRHFQGGKKALQIQKTWVKDEPPCAKTKFSVDTPHASTLSSPVKRKDTKHFVSSSRTLLRLQAEKLLSSAKNSDHEYCREKNLLKTVTDFPSNSALGQANGHRPRTDPQASDFPMKFNGESQSPGESGAIVITLSNHKRKGFCYGCCRGPEHHRNGGPLIPKQFQLNRHRRIKLSPLMMYEKLSMIRFRYRILRSQHFRTKSKVCKLRKAQRSWVQKVTGDHQETLRENGEGGSGSPFPSPEPKDPSCRQQPYFPDMDSNAVVKGTNSHVPDGHTKGSPFLGKELSLDEAFPDQQNGSATHAWDQSSCASPKWECTELIHDIPLPEHHSNTMFVSETEKEIATLGQENRTSSLSDDGVKLSVSGADTSVSSVDGPVSQKAVHSENSYQMEEDGSLKQNILSSELLDHPYCKSPLEAPLVCSGLKLENQVGGGKDSQKASPVDDEQLSVCLSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNRKPFINREITNYRARHQKCNFRIFYNKHMLDMDDLATLDGQNWLNDQVINMYGELIMDAVPDKVHFFNSFFHRQLVTKGYNGVKRWTKKVDLFKKSLLLIPIHLEVHWSLITVTLSNRIISFYDSQGIHFKFCVENIRKYLLTEAREKNRPEFLQGWQTAVTKCIPQQKNDSDCGVFVLQYCKCLALEQPFQFSQEDMPRVRKRIYKELCECRLMD
What is the function of this protein?
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins.  Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates.  Required for cell division.
What are the official names of this protein?
Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CEII9_CENEL
Sequence: KEGYLVNHSTGCKYECFKLGDNDYCLRECRQGYGKGAGGYCYAFGCWCTHLYEQAVVWPLPKKTCNA
What is the function of this protein?
Beta toxins bind at site-4 of sodium channels and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.  This toxin is active against mammals and lethal to mice.  Selectively modulates Nav1. 4/SCN4A, a sodium channel present in both denervated and innervated skeletal muscle.
What are the official names of this protein?
Beta-mammal toxin CeII9, Cell9.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KDPC_PSEAB
Sequence: MFKQLRPALASLLVLSLVTGVAYPLLVTGIAQLAFPEQANGSLLRDAEGKVLGSRLIAQKFDGEEWFHSRPSAGDYATVSSAASNLAPSNPALAERIARDAAQERIADQGPVPLALVTTSGSGLDPQLPPQAARYQALRVATARGLPLRLVEDLVESHTERPLVGPAVVNVLALNMALTGLKR
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HAT1_MAIZE
Sequence: MALKQKDTDAAATATGTKKRRRVFFSDTDAGVEANECMKVFLVWNPGEVSSVDCTAIQPFDLNHFFGEDGKIYGYKNLKINVWISAKSFHGYADVSFDETSDGGKGITDLKPVLQNIFGENLVEKEEFLHTFSKECEYIRTAVTNGSAIKHDGSYESDPAVEIVRVELQGAAAFLYSRLVPLVLLLVEGSTPIDIGEHGWEMLLVVKKATQEAGSKFELLGFAAVHNFYHYPESIRLRISQILVLPPYQGEGHGLGLLEAINYIAQSENIYDVTIESPSDYLQYVRSSIDCLRLLMFDPIKPALGAIVLSLKETNLSKRAQSLRMVPPADLMETVRQKLKINKKQFLRCWEILVFLSLDSQDHKSMDNFRACIYDRMKGEILGSASGTNRKRLLQMPTSFNKEASFAVYWTQEIEDEDEQTVEQQPEDLKTQEQQLNELVDIQIEEIAGVAKNVTSRCKDKMTELVVQ
What is the function of this protein?
Acetylates newly synthesized histones during DNA replication.  Highly specific in vitro for the non-acetylated H4 which is acetylated sequentially at 'Lys-12' and 'Lys-5' into a di-acetylated form.
What are the official names of this protein?
Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase HAT B, Histone acetyltransferase HAT-B-p50.
What is the protein family that this protein belongs to?
Belongs to the HAT1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: PB1F2_I02A7
Sequence: MEQGQDTPWTQSTEHTNIQKRGSGQQTQRLEHPNSTRLMDHYLRIMSPVGMHKQIVYWKQWLSLKNPTQGSLKTRVLKQWKLFNKQEWIN
What is the function of this protein?
Plays an important role in promoting lung pathology in both primary viral infection and secondary bacterial infection.  Promotes alteration of mitochondrial morphology, dissipation of mitochondrial membrane potential, and cell death.  Alternatively, inhibits the production of interferon in the infected cell at the level of host mitochondrial antiviral signaling MAVS.  Its level of expression differs greatly depending on which cell type is infected, in a manner that is independent of the levels of expression of other viral proteins.  Monocytic cells are more affected than epithelial cells.  Seems to disable virus-infected monocytes or other host innate immune cells.  During early stage of infection, predisposes the mitochondria to permeability transition through interaction with host SLC25A6/ANT3 and VDAC1.  These proteins participate in the formation of the permeability transition pore complex (PTPC) responsible of the release of mitochondrial products that triggers apoptosis.
What are the official names of this protein?
Protein PB1-F2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PB1-F2 family.
What are the subcellular locations of this protein?
Host mitochondrion inner membrane. Host nucleus. Host cytoplasm, host cytosol. Note=Inner mitochondrial membrane in most cells types. Otherwise is detected in the nucleus and cytosol.
Protein: TRP3_BANDI
Sequence: GPSSGFFGMR
What are the official names of this protein?
Tachykinin-related peptide 3, TKRP-3.
What are the subcellular locations of this protein?
Secreted.
Protein: VIRD2_AGRRH
Sequence: MPDRAQVIIRIVPGGGTKTLQQIINQLEYLSRKGKLELQRSARHLDIPLPPDQIHELARSWVQETGTYDESQPDEERQQELTTHIIVSFPAGTSQAAAYAASREWAAEMFGSGAGGGSYNYLTAFHIDRDHPHLHVVVNRRELLGHGWLKISRRHPQLNYDALRINMAEISLRHGIVLDASSRAERGIFERPITYAQFRRLERQARQIRFEDADLEQSSSQGDHPEFSQSPDTAPFEASAGRSEGMPYPNNRQNGSQVHLHEPAGFSNRAGGSVRIALETQRLAIFADDIESGSPPVSDVRAGNANADSDLPRSTVARTTDYSQRWSKRPRDDDEGPSGAKRVRLEGMAVGPEANAGERDSRGDPVAPPAETSRPSSLQDMARPNTATDPLAASGHLEQRRGTLSKRPRVEDDGEPSERKRARDDRSQDGRGGNRR
What is the function of this protein?
Tumor formation by A. tumefaciens involves the transfer and integration of a defined segment (T-DNA) of Ti plasmid DNA into the plant nuclear genome.  The virD operon encodes a site-specific endonuclease that cleaves at a unique site within both 24 bp direct repeats flanking the T-DNA.
What are the official names of this protein?
T-DNA border endonuclease VirD2.
Protein: BLI1_YEASL
Sequence: MGEQNKLYYDVEKLVNSLQESFDLDCAQSVSLFTSKSRSNEAWLEELENKFKLKDDVELDDVENLRAEIDMKLNMLEDKVSYYERLYKELEEFQNEIKIKTVVNNRRQSRTPK
What is the function of this protein?
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
What are the official names of this protein?
Biogenesis of lysosome-related organelles complex 1 subunit BLI1, BLOC-1 subunit BLI1, BLOC-1 interactor 1.
What is the protein family that this protein belongs to?
Belongs to the BLI1 family.
What are the subcellular locations of this protein?
Endosome.
Protein: LEUD_MARN8
Sequence: MRAFTQHQGTVAPMDRSNVDTDMIIPKQFLKSIKRTGFGPNLFDELRYLDEGKPDQDCSNRPLNPDFVLNQDRYKNASVLLARTNFGCGSSREHAPWALDDFGFRVIIAPSFADIFYNNCFKNGLLPIVLDEKVVDRLFRETEENEGYQLTVDLEAKTVTTPGGESFSFEVDDFRRHCLLNGLDDIGVTLEDADTIRAYEESRRKTAPWLFNTGN
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: EFPL_ECO81
Sequence: MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSPGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
Protein: SYP_STRPZ
Sequence: MKQSKLLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLPLANRTIEKFKTIMREEFEKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDNSDFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDGYSFHHNYEDLDVTYEDYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPARTDLDRWVVLDKSIASMDDIPKEVLEEIKAELAAWMISGEDTIAYSTESSYAANLEMATNEYKPSSKVAAEDALAEVETPHCKTIDEVAAFLSVDETQTIKTLLFVADNEPVVALLVGNDHINTVKLKNYLAADFLEPASEEEARAFFGAGFGSLGPVNLAQGSRIVADRKVQNLTNAVAGANKDGFHVTGVNPGRDFQAEYVDIREVKEGEMSPDGHGVLQFARGIEVGHIFKLGTRYSDSMGATILDENGRTVPIVMGCYGIGVSRILSAVIEQHARLFVNKTPKGDYRYAWGINFPKELAPFDVHLITVNVKDQVAQDLTAKLEADLMAKGYDVLTDDRNERVGSKFSDSDLIGLPIRVTVGKKAAEGIVEIKIKATGDSIEVNAENLIETLEILTKEH
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.