PharMolix/UniProtQA huggingface dataset:
Protein: RL20_SALAI
Sequence: MARVKRAVNAQKKRRTLLATASGYRGQRSRLYRKAKEQVLHSMQYSYRDRRDRKGDFRQLWIQRINAGARANGLTYNRLIQGLKLAGVEVDRKILADLAVNDAAAFAAIVELARAAVAEQGTGGAASQAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: RL27_PSE14
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKMYGGQAIIPGNIIVRQRGTQFHAGYGVGMGKDHTLFAKVEGVIKFQVKGAFGRRYVSIVPKTEVSAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: HEM6_XANCB
Sequence: MNEFDRVRDYLTDLQDRICAAVEAIDGKARFAEDLWQRAEGGGGRTRILRDGAVFEQAGIGFSDVSGARLPPSASAHRPELAGATWRACGVSLVFHPHNPHIPTTHANVRYFRAERDGEMVAAWFGGGFDLTPFYPVDEDVMHWHRTAQALCAPFGEERYAAHKRWCDEYFFLRHRDETRGVGGLFFDDLGQDFERDFAYQRAVGDGFLDAYLPIVERRKDTPYGEAERAFQLYRRGRYVEFNLVYDRGTLFGLQSGGRAESILMSLPPQVRWEYGFQPQPGSAEARLADYLIPRDWLG
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_GEOSW
Sequence: MSEMIRITFPDGAVKEFPKGTTTEQIAASISPGLKKKAIAGKLNDRFIDLRTPIQEDGSISIITQDMPEALDILRHSTAHLMAQAIKRLYKNVKLGVGPVIENGFYYDIDMEESLTPEDLPKIEQEMRKIVKENLEIVRKEVSREEAIRLYEEIGDDLKLELINDIPEGETISIYEQGEFFDLCRGVHVPSTGKIKEFKLLNISGAYWRGDSNNKMLQRIYGTAFFKKEDLDEYLRQLQEAKERDHRKLGKELELFMTSQKVGQGLPLWLPKGATIRRIIERYIVDKEIELGYQHVYTPVLGSVELYKTSGHWDHYKDNMFPPMEMDNEQLVLRPMNCPHHMMIYKSKIHSYRELPIRIAELGTMHRYEMSGALSGLQRVRGMTLNDAHIFVRPDQIKDEFKRVVNLILEVYKDFGLDEYSFRLSYRDPHDKEKYYDDDEMWEKAQNMLREAMDELGLEYYEAEGEAAFYGPKLDVQVRTALGKDETLSTVQLDFLLPERFDLTYIGEDGKPHRPVVIHRGVVSTMERFVAFLIEEYKGAFPTWLAPVQVEVIPVSPAAHLDYAYKVKEALQSQGFRVEVDERDEKIGYKIREAQIQKIPYMLVVGDKEMAENAVNVRKYGEQKSETMSLDDFIAALKAEVRRN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA2_PARD8
Sequence: MNSLVILLGPTGVGKTELSLQVAERFGSPIISSDSRQLYKDLPIGTAAPTPEQMARVKHYMVGTLSLTDYYSASNFEEDVVSLLSELHKTIPTVVMTGGSMMYIDAVCKGIDDIPTVTPEIRDALYMQFETEGLAPILAELKEADPVHYEEVDRNNYKRVIHAVEICRMTGKPYSSFRTNIKKERPFRIIKVGLNRDRDELCDRINQRVDQMMSEGLLEEARRAYPFRHLNSLNTVGYKELFNYFSGEWTLDLAVEKIKRNSRVYARKQMTWFKRDPEITWFHPDETEAIFTHLSQQII
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase 2, Dimethylallyl diphosphate:tRNA dimethylallyltransferase 2, DMAPP:tRNA dimethylallyltransferase 2, DMATase 2, Isopentenyl-diphosphate:tRNA isopentenyltransferase 2, IPP transferase 2, IPPT 2, IPTase 2.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ESAB_STAAW
Sequence: MNQHVKVTFDFTNYNYGTYDLAVPAYLPIKNLIALVLDSLDISIFDVNTQIKVMTKGQLLVENDRLIDYQIADGDILKLL
What is the function of this protein?
Seems to regulate secreted factors that contribute to the establishment of persistent infections in the host.
What are the official names of this protein?
Type VII secretion system accessory factor EsaB.
What is the protein family that this protein belongs to?
Belongs to the EsaB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_THENN
Sequence: MAKKVAAQIKLQLPAGKATPAPPVGPALGQHGVNIMEFCKRFNAETADKAGMILPVVITVYEDKSFTFIIKTPPASFLLKKAAGIESGSSEPKRKIVGKVTRKQIEEIAKIKMPDLNANDLEAAMRIIEGTARSMGIEVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: GRPE_TREDE
Sequence: MKKNHEKHADKKEAAKEELEKDLQPKDESAVKDEQGAGCGCETSKENPQEDKAEQNSSTGGKCEKNDDVLSPEKRIEELEAKCRDWQDQYLRKAADFENYRKRMIREKQEAIDYANSNLLLDLVQVLDDFDRAIDAGKTQGGESVNNAFVEGVVMIKNQMVSMLSSKYGLSYYPAKGEAFDPNLHEAVSMIQSPDVKEAVVGEELQKGYKLKERVIRHSKVMVLMPAEKQDEKKAEESEAADKKNEN
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BFRB_MYCTE
Sequence: MTEYEGPKTKFHALMQEQIHNEFTAAQQYVAIAVYFDSEDLPQLAKHFYSQAVEERNHAMMLVQHLLDRDLRVEIPGVDTVRNQFDRPREALALALDQERTVTDQVGRLTAVARDEGDFLGEQFMQWFLQEQIEEVALMATLVRVADRAGANLFELENFVAREVDVAPAASGAPHAAGGRL
What is the function of this protein?
Iron-storage protein that displays ferroxidase activity, catalyzing the oxidation of Fe(2+) ions into Fe(3+) ions, that can then be deposited as a ferric-oxide mineral core within the central cavity of the protein complex.
What are the official names of this protein?
Ferritin BfrB, Bacterioferritin, Non-heme ferritin Ftn, Nox19.
What is the protein family that this protein belongs to?
Belongs to the ferritin family. Prokaryotic subfamily.
Protein: PVK1_PRAMA
Sequence: EAAGLLAFPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
CAPA-Periviscerokinin-1, CAPA-PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LFTR_LEPBL
Sequence: MKDFSDFFRNPHIWDREIVAVGGDLSPERLLYAYKNGIFPWSDQPILWYCLDPRGIFDLNKLHISKRLKRKINQKRYTITFNRAFEQVMRCCAYRPGEETWITDLFIKSYTEFHKLGYAHSIEVWDENGNLGGGVYGVAIGNFFAGESMFSFISDFGKIGLFHLFEALKKDQFTLFDTQQLNIVTLCLGAYQIPKKEYLRRLESAVASGKKWNPLRTVF
What is the function of this protein?
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.
What are the official names of this protein?
Leucyl/phenylalanyl-tRNA--protein transferase, L/F-transferase, Leucyltransferase, Phenyalanyltransferase.
What is the protein family that this protein belongs to?
Belongs to the L/F-transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAX_I80AD
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKLQEPCADSQTKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: RK34_TRICV
Sequence: MTKRTLSNKTRYSILKLSGFRARMSTAQGRKTLKARRKKGRKQLAVRR
What are the official names of this protein?
50S ribosomal protein L34, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CYSD2_MARN8
Sequence: MNMTTYNLTHLKQLEAESIHIIREVAAEFDNPVMLYSIGKDSAVMLHLALKAFYPGKPPFPLLHVDTTWKFRDMISFRDHVAEKFGLDLIVHINEEGVKQGVGPFTHGSAKHTDIMKTQSLKQALNKYKFDAAFGGARRDEEKSRAKERVYSFRDEHHRWDPKNQRPELWNIYNGKVNKGESIRVFPLSNWTELDIWQYIYLENIDIVPLYYAAVRPVVERDGTLIMVDDDRMPLKEGEKPMMKSVRFRTLGCYPLTGAIESEANTLPDIIQEMLLATSSERQGRVIDHDSAGSMEQKKREGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2 2, ATP-sulfurylase small subunit 2, Sulfate adenylate transferase 2, SAT 2.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: ODC_BOVIN
Sequence: MSAKPSVGFVNEASRQILAGGSAGLVEICLMHPLDVVKTRFQIQRCTTDPNSYKSLGDSFRMIFRTEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLLGYVSLSPALTFAVAGLGSGLTEAIVVNPFEVVKVGLQANRNRFTEQPSTMSYARHIIKKEGLGLGGLNKGFTATLGRHGVFNMVYFGFYFNVKNIIPVNKDPTLEFLRKFGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYKTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWLQENW
What is the function of this protein?
Transports dicarboxylates across the inner membranes of mitochondria by a counter-exchange mechanism.  Can transport 2-oxoadipate (2-oxohexanedioate), 2-oxoglutarate, adipate (hexanedioate), glutarate, and to a lesser extent, pimelate (heptanedioate), 2-oxopimelate (2-oxoheptanedioate), 2-aminoadipate (2-aminohexanedioate), oxaloacetate, and citrate.  Plays a central role in catabolism of lysine, hydroxylysine, and tryptophan, by transporting common metabolite intermediates (such as 2-oxoadipate) into the mitochondria, where it is converted into acetyl-CoA and can enter the citric acid (TCA) cycle.
What are the official names of this protein?
Mitochondrial 2-oxodicarboxylate carrier, Solute carrier family 25 member 21.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PNP_KOCRD
Sequence: MEGPEIQSAEAVIDNGSYGKRVVRFETGRLARQAAGSAMVYIDEETSMLSATAVGKHPREGFDFFPLTVDVEERMYAAGRIPGSFFRREGRPSTDAILTCRLIDRPLRPAFGKGLRNEVQVVVTVMSIAPDEIYNTVAINAASMSTTLSGMPFQGPVGGVRMALMAEENGGHQWIAFPKHSQLENAVFDMAVAGRVVTTKDGGQDVAIMMVEAEATDNAWELIKGQGAVAPSEELVAEGLEASKPFIKALCDAQADLAARNRKPELDLPRFGGFGDDAAQAVEQFVGERMAQVYSIAGKQEREAATDELHHDTLAELTGEGKPFEGRADEVNGAYQALTKQTVRQRILKDKVRIDGRGLTDIRQLSAEVDVLPRVHGSALFERGETQIMGVTTLNMLKMEQQIDSLSPVKHKRYIHHYNFPPYSTGETGRVGSPKRREIGHGALAERAITPVLPSREEFPYAIRQVSEALGSNGSTSMGSVCASTLALYNAGVPLRAPVAGIAMGLVSDTVDGEVQYAALTDILGAEDALGDMDFKVAGTREFVTAIQLDTKLDGIPASVLASALTQAREARLYILDVLTSAIDAPDEMSEFAPRVISVTVPVSKIGEVIGPKGKMINQIQEDTGTDISIEDDGTVYIGATDGPSAEAARSAINAIANPQVPEVGERYLGTVVKTTTFGAFVSLTPGKDGLLHISEMRQLNDDKRVNEVDDVLSVGQKVQVEITKVDDRGKLSLAPVVAGSDSDAASDDEN
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBX38_CAEEL
Sequence: MYSCTSPSGIKVSLSTPEIWEEFYPKTEMIVTRNRGRVIFPHLDYIIKGLDPGSLYSIYIHLERVDGIKYKFDAGEWKEFAKGDPILPIQYKEHPRGKRTGAEWMSEPVSFAHIKITNNPEIKDQKVILVQSMHKHIPVVTVKQVRHYKTGYQEDFSGEQFRLEATEFMVVTAYQNEILKNLKVHHNKFASGFRSNGKRRLSSDSENSENSPPKRSKLVTPPTISPQIDLPQQTPYYFNQNFVAPQNYQPQFASAQNYNFEVQNNAQLAWNMYYQKQYEFWWQQQQMMMPGQPQELKNEFQSL
What is the function of this protein?
Transcription factor (By similarity).  Required for mesodermal induction, acting redundantly with transcription factor tbx-37 (PubMed:15056620).  Together with tbx-37, acts by inducing cell fates in the AB lineage, thereby playing a role in development of the anterior pharynx (PubMed:15056620).
What are the official names of this protein?
T-box protein 38.
What are the subcellular locations of this protein?
Nucleus.
Protein: SHE9_AJECN
Sequence: MPALSIPQTVFLCAEGREGSRRGEERFHAAKERWEGQSGGAERGGNAGYFHKKGFRDIEKLKQDILAQEQRVRETRTCVQEAKEAYSTAINRRSASQREVNELLQRKHAWSPTDLERFTSLYRSDHANERAETDAQEALVVAEREAEEAAALLSKSILSRYHEEQIWSDKIRRMSTWGTWGLMGVNVLLFLIFQVAVEPWRRRRLVKGFEEKVMEALERENGMKEGVGAVEGATLRDGATTVPAAAAAPSLIAEPVTPTFSNISDETPAGPSDAAMFTEQDVPDPAVVSATAPTLTALQPNKQSQSSTSALLLPPDASLSPDSWRQTIHDLFGERRITLSQRELTTVALESAAAGAAVMGVLIALFRPR
What is the function of this protein?
Required for the maintenance of the structure of the mitochondrial inner membrane.  Involved in mitochondrial morphology.  Causes growth arrest when highly overexpressed (By similarity).
What are the official names of this protein?
Sensitive to high expression protein 9 homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SHE9 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS7_LEPIC
Sequence: MSRRRGKVEPRKITPDPVYNDVQVAKFINCLMLSGKKSVAEQLFYDALEIIQKKTGNDPYTTFREALENAKPQVEVKSRRVGGVTYQVPVEVRPERRLALGIRWLIRYSRDRNEKGMAAKLAAEFIEAQKGTGSAIKKKEDIRKMAEANKAFSHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: S39A7_DANRE
Sequence: MRVFSKSLLLIAVGILMSQQTLAHSHHHHGHGDGGCHGHSHGGAKMHHGASKWSAEANLPHAEEEHHVHDHGHTHNHAHDHGHAHSHGDIHDHGHAHKHGHAHDHGAEKSKKVVEAGKRNMVELWMQAIGATLLISAAPFLILFLIPVQSNTDQHQNLLKVLLSFASGGLLGDAFLHLIPHALEPHSHHSQPHSEESHGQSHGEESHGHSHGAAHGHMMSVGLWVLGGIVAFLVVEKFVRLLKGGHSHSHSHSPSAPKSKDSDEEDDKKGQKKGEKDKVVSQQKPTKKTVETSSDIKVSGYLNLAADFTHNFTDGLAIGASFLVGPAVGAVTTITILLHEVPHEIGDFAILVQSGCTKRKAMCLQLLTAVGALAGTACSLLAEGVGDAATAWILPFTAGGFVYIATVTVLPELLAGHSSFWQSLLEILALLFGVGMMVLIAEYE
What is the function of this protein?
Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels (By similarity).  Plays a role in maintaining zinc homeostasis and organism development especially in eyes, brain, and gills (PubMed:22912764).
What are the official names of this protein?
Zinc transporter Slc39a7, Histidine-rich membrane protein Ke4, Solute carrier family 39 member 7, Zrt-, Irt-like protein 7, ZIP7.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family. KE4/Catsup subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein.
Protein: SYH_RICBR
Sequence: MTDKLQPLRGMKDLLPDDYKVHDYIIKKAKEVGELYGYKQMSTPILEYTKVFNRSMGESSDVISKEIYSFLDKSDESVALRPEFTAGIVRAFISNGLQHKLPLKLFSTGPVFRYDRPQAGRQRQFHQLNYEYLGAKGAISDAETLKLAVDILQSLEVLADTTLELNSLGCSQSRSTYQQKLVEYLNDFKDELSEDSKIRLTKNPMRILDSKSEVDQKIVANAPVLSEYYTEESKKYFEELLKYLDILGVKYTINARLVRGLDYYCHTAFEFTTTKLGSQSTILAGGRYDGLSRIMGNNDEIPAIGFAAGIERIALMREYNIDSVTPIFVLPIGENNISHSLKIADQLRLHNIPVLIEVSGKMAKRMQRALNENAKFIVFIGDEEQANNNLKIKDLEKQEEYILDFSKTIELLKKS
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ7_HERSE
Sequence: MQFVDELISDFDKALRVINGVVFESRPNPGRGLPDGVMSEAEKRHAAGLMRVNNVGEVCAQALYDAQGRFAQKAEIKNAFARAGIEEEDHLAWTAERLRELGSHTSLLNPLWYGGAYVLGSIAARLGDARNLGFVSETERQVEHHLMGHLDKLPAQDNRSRAIVDQMRIDEIEHGQAARDLGAAEMPAPVKGLMKAMAKVMTTVAYRI
What is the function of this protein?
Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
What are the official names of this protein?
3-demethoxyubiquinol 3-hydroxylase, DMQ hydroxylase, 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the COQ7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TX16C_CYRSC
Sequence: MNTVRVTFLLVFVLAVSLGQADEDGNRMEKRQKKTEAENLLLPKLEELDAKLWEEDSVESRNSRQKRCNGKDVPCDPDPAKNRRCCSGLECLKPYLHGIWYQDYYCYVEKSGR
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U10-theraphotoxin-Hs2a, U10-TRTX-Hs2a, HWTX-XVIc.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 02 (HWTX-XVIc) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DCUP_ECO55
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLVRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLG_ALKCK
Sequence: MTVRVGVIGTGAIGQDHIRRLECKLSGAKVTAVTDVNQDLARKVANTYAKQATVYANDRELIAARDVDAVLVASWGPAHEASVLAALEAGKRVFCEKPLATTADGCMRIVEAEMAHGKRLVQVGFMRRFDSGYLQLKQALEQELVGEPLMVRCIHRNVESAESYTTDMAITDTLIHEIDVLHWLLNDEYQHVRVLYPKKTKHALPHLQDPQLVLLETKKGVIIQAEIFVNCKYGYDIQCEIAGEEGVISLPDVPAVRLCSNGRKGTEVLQDWKKRFEAAYDVELQAFIDDGLKDEPASGPSAWDGYVAAVTADACVKAQESGREESIELPKKPAFYQHSAATPEQV
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively.
What are the official names of this protein?
Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, MI 2-dehydrogenase/DCI 3-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: SSRP_MYCGA
Sequence: MRLLVNNKKAKYNYELLDKYEAGISLSGNEVKSLALHHGKLDDSYVIIRKNEAYLLNLLIPKYKFDTSKVLNETRTRKLLLHKSEILKIDLIKKQHSLVIIPYQIYFVNNKIKVSIYLARPKKRYDKRQTIKEREINKKIRKY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: LLDD_XANOR
Sequence: MIISAASDYRAAAQARLPPFLFHYIDGGAYAEHTLRRNVSDLADVALRQRVLRNMSDLRLSTELFGETLAMPVALGPVGLTGMYARRGEVQAARAAAARGIPFTLSTVSVCPIEEVAPAIERPMWFQLYVLKDRGFMRNALERAKAAGVTTLVFTVDMPTPGARYRDAHSGMSGPNASLRRMLQAVTHPRWAWDVGVLGKPHDLGNISAYRGNPTGLQDYIGWLGANFDPSIAWKDLEWIREFWTGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGELKILADSGIRSGLDVVRMLALGADAVLLGRAFVYALAADGQAGVENLLTLIEKEMRVAMTLTGTHSIAQISADALSRVTREQANAVSP
What is the function of this protein?
Catalyzes the conversion of L-lactate to pyruvate.  Is coupled to the respiratory chain.
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SCPA_LISMF
Sequence: MVEMNFKVDAFEGPLDLLLHLIGQLEVDIYDIPMAEITDQYMEFVHTMQEMELDVASEYLVMAATLLAIKSKMLLPKQELEIDYDTLEEEEDPRDALVEKLMEYKRFKEAAKELKEKEAERSFYFSKPPMDLAEYDDGTKVAELDVSLNDMLSAFNKMLRRKKLNKPLHTRITTQEISIDQRMDSVLEKLNLQVNHRLRFDELFEEQTKEQLVVTFLALLELMKRKLVEVEQAESFADLYVQGKGEEIS
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein A.
What is the protein family that this protein belongs to?
Belongs to the ScpA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: ISPD_SHIF8
Sequence: MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVTRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDVQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.