PharMolix/UniProtQA huggingface dataset:
Protein: H33_MOUSE
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TM138_DANRE
Sequence: MLQTNNYSLVLLIQLALLTFDLFVNSFSELLRSAPVIQLVLFIIQDIGILFNVIIILLMMFNTYVFQVGLVSLLLERFRAMLILSALYLTLSICFHCWVMNLRWMESNRFVWTDGLQVLFVFQRIAAVLYYYFYKRTTEYLGDPRLYEDSPWLRDAFARARQ
What is the function of this protein?
Required for ciliogenesis.
What are the official names of this protein?
Transmembrane protein 138.
What is the protein family that this protein belongs to?
Belongs to the TMEM138 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Cell projection, cilium. Note=Localizes to vesicles en route to the base of cilium.
Protein: RS3_CUPPJ
Sequence: MGQKIHPTGFRLAVSRNWASRWYANNTKFAGMLKEDIEVRDFLKKKLKNASVGRVVIERPARNARITIYSSRPGVVIGKKGEDIELLKAELQRRMGVPVHVNIEEIRKPETDAQLIADSITQQLERRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLRADIDYGFSEAETTYGIIGVKVWVYKGDHLGRNDAPVVEEPQDDRRRRPGRPEGRRREGEGRPGGNRRGGAGAGRRAAPGDAKSGE
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: RK20_DRANE
Sequence: MTRIKRGYIARRRRTKLRLFASSFRGAHSRLTRTMTQQRIRALVSAHRDRGKRKRDFRRLWITRINAVIHETGVFYSYNRFIHNLYKKQLLLNRKILAQIALLNRSCLYTISNEIKE
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RHAT_ECO24
Sequence: MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPDFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVIIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
What is the function of this protein?
Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system).
What are the official names of this protein?
L-rhamnose-proton symporter, L-rhamnose-H(+) transport protein.
What is the protein family that this protein belongs to?
Belongs to the L-rhamnose transporter (TC 2.A.7.6) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IHFB_PSEMY
Sequence: MTKSELIERIVTHQGQLSSKDVELAIKTMLEQMSQALATGDRIEIRGFGSFSLHYRAPRVGRNPKTGQSVRLDGKFVPHFKPGKELRDRVNEDES
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CH602_CORGB
Sequence: MAKIIAFDEEARRGLEKGLNTLADAVKVTLGPKGRNVVLEKAWGAPTITNDGVTIAREIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGSNPMGIKRGIEKAVAQVTEKLLEAAKEVETEEQIAATAGISAADPAIGAQIAKAMYAVGGGKLNKDSVITVEESNTFGVELEVTEGMRFDKGYISGYFATDMERLEAVLEDPYILLVSGKISNIKDLLPLLEKVMQSGKPLLIISEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAQLQDIAVLTGGQVISEEVGLSLETADLPLLGQARKVVVTKDDTTIVDGAGSEAQIEGRVNQIRVEIENSDSDYDREKLNERLAKLAGGVAVLKVGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQAAHVLDNDLELSGDEATGVRIVREALTSPLKQIAANAGLEPGVVADKVSQLPQGEGLNAATGEYVDLMAAGINDPVKVTRSALQNAASIAALFLTTEAVVADKPQPAGAAGMPGADEMGGMGGF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, Chaperonin-60 2, Cpn60 2.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRRB_STAAW
Sequence: MMSRLNSVVIKLWLTIILIVTTVLILLSIALITFMQYYFTQETENAIREDARRISSLVEQSHNKEEAIKYSQTLIENPGGLMIINNKHRQSTASLSNIKKQMLNEVVNNDHFDDVFDKGKSVTRNVTIKEKGSSQTYILLGYPTKAQKNSHSKYSGVFIYKDLKSIEDTNNAITIITIITAVIFLTITTVFAFFLSSRITKPLRRLRDQATRVSEGDYSYKPSVTTKDEIGQLSQAFNQMSTEIEEHVDALSTSKNIRDSLINSMVEGVLGINESRQIILSNKMANDIMDNIDEDAKAFLLRQIEDTFKSKQTEMRDLEMNARFFVVTTSYIDKIEQGGKSGVVVTVRDMTNEHNLDQMKKDFIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAIVLDESKRLNRLVNELLNVARMDAEGLSVNKEVQPIAALLDKMKIKYRQQADDLGLNMTFNYCKKRVWSYDMDRMDQVLTNLIDNASRYTKPGDEIAITCDENESEDILYIKDTGTGIAPEHLQQVFDRFYKVDAARTRGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLPKPE
What is the function of this protein?
Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation.  Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate.  Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to SrrA.  In turn, SrrA binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression.
What are the official names of this protein?
Sensor protein SrrB, Staphylococcal respiratory response protein B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPL_STROR
Sequence: MNLTFFGLCLACMGVSLAEGMLMNGLFKSAARQPDIIPQLRSLMIMGIAFIEGTFLVTLVFSFVIK
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NS1_I07A0
Sequence: MDSHTVSSFQVDCFLWHVRKQVADQDLGDAPFLDRLRRDQKSLKGRGSTLGLNIETATCVGKQIVERILKEESDEALKMTMASALASRYLTDMTVEEMSRDWFMLMPKQKVAGPLCVRMDQAIMDKNIILKANFSVIFDRLENLTLLRAFTEEGAIVGEISPLPSFPGHTNEDVKNAIGVLIGGLEWNDNTVRVSETLQRFAWRSSNETGGPPFTTTQKRKMAGTTRSEI
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: RPOB_BORHD
Sequence: MIKRVHLGQGKAEEILDLPNLIEIQLNSYEKFLQLERLKTNRPLLNEGLESVFRDVFPMKSSNGEVALEYEKYYIEYNSLSFTEKECKRKGQSYEAVLKIRLNLQFLTTGEIRQKDVYMGTIPLMTDRGTFIVNGAERVIVSQIHRSPGVVFYKEKDLYYARIIPYRGSWLEFEIDSKKDYLYVKIDRKKRILVTLFLRALGLNTRERIIETFYKIRKIEVNEDTKREITGQYLATNIIIKENMTYRAGDKITLQDIEDFLQNGVKEIDLIDFDGYDSVPGKHFISSDVILNCFEKEDAYFSLKDGFKELSRESVMLAVYSVLLPGEPISIDNAESDLRNVFFSEKRYDLGHVGRYKLSKKFGLDDLTTSVLTMTDIVNTISHLLRIYDGHDVLDDIDHLGNRRVRSVGELLTNIYKGAMSRVEKIAKDRMSNKEVFNLKPQELISVKPIVSAVKEFFATSQLSQFMDQVNPLAELTHKRRLNALGPGGLSRDRAGFEVRDVHYTHYGRMCPIETPEGPNIGLIVSLATYAKVNDYGFLETPYRKVVDGKVTDEIEYLSAIDEEKKCIAQANAAVNAEGNYIDDLISVRVSGDYTTMIPKNIDYMDVSPRQLISVSSALIPFLEHNDANRALMGSNMQRQAVPLLFPQPPIVGTGMERIVAKDSGVVVKAKRSGIVVLATSKKIVIRPEDAADDHDLDEYELAKYERTNQDTSFNHSVLVKEGQVVNKGEIIADGPATRYGEVALGNNLLVGFIPWNGFNYEDAILISERIIKEDLYTSIHIKEFSIEVRETKLGPEKVTADIPNVSGKILNKLDENGIVRIGTYVKPGDILIGKVTPKSEGDITPEFKLLTSIFGEKAKDVKNNSLKVPHGTEGTVIDVQRITKDDVSNLPPGVDEILKVYIAKKRKLKEGDKMAGRHGNKGVVAKILPVEDMPYLADGTPLDICLNPLGVPSRMNIGQLMESQLGLAGKYLGEYYDVPVFESATNECIQEKLKKAGFNETSKAVLYDGYTGEPFENEVMVGIIYMLKLHHLVDDKMHARSTGPYSLVSQQPLGGKAQFGGQRLGEMEVWALEAYGAAHTLQELLTVKSDDMSGRVKIYENIVKGIPTNVSGIPESFNVLMQELRGLGFDLSIYDDKGNQIPLTEKEEELINKT
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL24_MACCJ
Sequence: MHIKKGDKVIVITGKDKGKTGTVIEALPKRDRVVVEGVNIVKKHQKPTQMNPEGGITEFEAAIHVSNVMLLDPKTNKPTRVGTKIEDGKKVRVAKKSGEIIK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL22_CENSY
Sequence: MGDFGYSFEGYDPTRHVRASLREKQISHKHAREISLHIRGMTVEKARDFLQAVIEKKRAVPFRRFKRQVGHRSDPGVMAGRYPEKSAAEFIKLLDNLESNAEYKGMDLDRLTIVGAVAHKGILIKRFIPRAMGRSTPKNNVLTHVELVAREA
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: SYR_ECO81
Sequence: MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFHEMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEINEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXOC8_RAT
Sequence: MSDSGASRLRRQLESGGFEARLYVKQLSQQSDGDRDLQEHRQRVQALAEETAQNLKRNVYQNYRQFIETAREISYLESEMYQLSHLLTEQKSSLESIPLALLPAAAAGASTGEDTAGAGPRERGAAQAGFLPGPAGVPREGPGTGEEGKQRTLTTLLEKVEGCRDLLETPGQYLVYNGDLVEYEADHMAQLQRVHGFLMNDCLLVATWLPQRRGMYRYNALYPLDRLAVVNVKDNPPMKDMFKLLMFPESRIFQAENAKIKREWLEVLEETKRALSDKRRREQEEAAALRAPPPVTSKGSNPFEDEAEEELATPEAEEEKVDLSMEWIQELPEDLDVCIAQRDFEGAVDLLDKLNHYLEDKPSPPSVKELRAKVDERVRQLTEVLVFELSPDRSLRGGPKATRRAVSQLIRLGQCTKACELFLRNRAAAVHTAIRQLRIEGATLLYIHKLCHVFFTSLLETAREFETDFAGTDSGCYSAFVVWARSAMGMFVDAFSKQVFDSKESLSTAAECVKVAKEHCQQLGEIGLDLTFIIHALLVKDIQGALLSYKEIIIEATKHRNSEEMWRRMNLMTPEALGKLKEEMRSCGVSNFEQYTGDDCWVNLSYTVVAFTKQTMGFLEEALKLYFPELHMVLLESLVEVILVAVQHVDYSLRCEQDPEKKTFIRQNASFLYDTVLPVVERRFEEGVGKPAKQLQDLRNASRLLRVNPESTTSVV
What is the function of this protein?
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
What are the official names of this protein?
Exocyst complex component 8, Exocyst complex 84 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the EXO84 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Cell projection. Note=Binds lipids with phosphatidylinositol 3,4,5-trisphosphate groups (By similarity). Perinuclear in undifferentiated PC12 cells. Redistributes to growing neurites and growth cones during NGF-induced neuronal differentiation (PubMed:12954101). Localizes at the leading edge of migrating cells (PubMed:21658605).
Protein: TRHO_RHIME
Sequence: MTDMLTTSRRPETPGQFLVAALYHFVSFPRFADFREPLQAICDANGVKGTLLLAHEGINGTIAGTEEGIAAVLACVRAQPEFAGLIHKESRASAMPFLRMKVRLKKEIVTMGVENIDPKKVVGTYVEPKDWNALISDPETLVIDTRNDYETAIGLFQGAVDPKTKTFREFPEWVRNNSGLHNKPKIAMYCTGGIRCEKATAFMKEQGFEEVYHLKGGILKYLEEIPPEESLWEGACFVFDERVSVTHGLQEGEHTLCHACRQPLTPEDLQSPLHEEGVSCIHCHDTRTEEDRERYRQRQRQIMLAKKRGARHLGS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: MTND_METCA
Sequence: MSLLTIHPESGTSAPEIIREGDAIAARLAEIGVLFERWQAGRAFEPDAEQQTILAAYADSVERLKAKYGFESADVISVGPDHPQKDELRARFLREHTHSDFEVRFFVEGRGLFYLHPGDRVYAILCERGDLLSVPSNTRHWFDMGAEPCLKCIRLFTTAEGWVADFTGSDIGDRFPRLEDYLKHYA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: GRPE_ECO81
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKD
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXB_SALDC
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKIAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: IL6_RAT
Sequence: MKFLSARDFQPVAFLGLMLLTATAFPTSQVRRGDFTEDTTHNRPVYTTSQVGGLITYVLREILEMRKELCNGNSDCMNSDDALSENNLKLPEIQRNDGCFQTGYNQEICLLKICSGLLEFRFYLEFVKNNLQDNKKDKARVIQSNTETLVHIFKQEIKDSYKIVLPTPTSNALLMEKLESQKEWLRTKTIQLILKALEEFLKVTMRSTRQT
What is the function of this protein?
Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability.  Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF.  Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance.  'Trans-signaling' in central nervous system regulates energy and glucose homeostasis.  Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity).  Also acts as a myokine (By similarity).  Plays a protective role during liver injury, being required for maintenance of tissue regeneration.  Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection.  Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
What are the official names of this protein?
Interleukin-6, IL-6.
What is the protein family that this protein belongs to?
Belongs to the IL-6 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CY098_POSPM
Sequence: MPTTLRMLNNNLLIVIGTFAVCVYIVLQRSKARLPLPPGPRKWPLIGNLLDMPGGRAWLKYAEWSREYGSDIIHLSAAGTSILVLNSAELVNELMEKRSAIYSSRAQLTMLHELMGWKDAFSFAPTNPTWRAQRKIFMQALNPNNAALFHGKQLRATHELLWRLHKGPANLFHELHHWAAILIMDITYGIRGDAADPYIETAVEALDSMAIAGAPGAFLVDAVPLLRHMPEWTPGAGFKRQAREWNVLRQKMANRPFIAAKQQITSGSYTPSLVSNALEAVDKNQDLAEQEELIKGAAVTSYGGGSDTVVAAVSAFVLAILQHPEIQAKAQRQLDEVLGHGELPSFQDVQSLPYITALVKEVLRHNPVTPLAIPHLLSEDDTWDGYWLPKGSIVMANAWAILHDENTYPDPMPFNPDRFLRPDGKLDETVKDPATASFGFGRRLCPGRHIALSSIWISVASILACYVIRKEVDAAGREVVPDGEWYGGPTLFNRPLPFKCRFTPRSKAAEAIIVSLENTV
What is the function of this protein?
Cytochrome P450 monooxygenase that is able to use pyrene, phenanthrene, 3,5-dimethoxy-trans-stilbene and 3,5,4'-trimethoxy-trans-stilbene as substrates for oxidation.
What are the official names of this protein?
Cytochrome P450 monooxygenase 98.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PEPT_STRPD
Sequence: MKYDNLLDRFIKYVKVNTRSDPDSETTPSTESQEAFALTILKPEMEAIGLQDVHYNPVNGYLIGTLPANNPTLTRKIGFIAHMDTADFNAENVNPQIIDNYQGGDITLGSSNYKLDPKAFPNLNNYIGQTLITTDGTTLLGADDKSGIAEIMTAIEFLTSQPQIEHCDIKVAFGPDEEIGVGADKFEVADFEVDFAYTMDGGPLGELQYETFSAAALEVTFLGRNVHPGTAKDQMINALQLAIDFHEKLPAKERPEYTDGYQGFYHLTGLTGTVEEARASYIIRDFEEASFEARKVKVENIAQSMNAQLGTKRVLVELNDQYYNMKKVIEKDMTAIELAKEVMEELAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQTMERAVDVIIGLVCKA
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRDMT_ARATH
Sequence: MAEQELQRINEKKPWQVLEFYSGIGGMRYSLMASGIVSEVVEAFEINDSANDVYQHNFKHRPYQGNIQSLTAADLDKYNADAWLLSPPCQPYTRQGLQKHSGDARAFSFLRILELIPHTTKPPQMLFVENVVGFETSDTHMEMIGTLTKLDYVTQEFILSPLQFGVPYSRPRYFCLAKRKPLPFKSQHSNNKLLWSPDPLYGRDDQVEFGKCQAEEGLDKLLEFCKPVEKFLELAAHVDGEPSSVDDSENGSKDCCGQEGDSVPDSVHQYLVPVSLIERWGNAMDIVYPDSKRCCCFTKSYYRYVKGTGSLLATVQPKIKGKESCLKEQRLRYFTPREVANFHSFPEDFEFPKHISLRQRYAMLGNSLSVAVVAPLLRYLFDS
What is the function of this protein?
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp) (By similarity).  Represses gene expression at transcription level, probably by regulating histone deacetylation and epigenetic regulatory network (PubMed:20331964).
What are the official names of this protein?
tRNA (cytosine(38)-C(5))-methyltransferase 2, AtDNMT2, DNA (cytosine-5)-methyltransferase-like protein 2, Dnmt2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSTB_TROWT
Sequence: MTSLLEIKDLTAFYGPLRAIKDVSLSIQEGSVTALIGPSGCGKSTLLRTLNRMHELSPGAKVKGQVLLDGRDLYQLDPVYVRQEVGMIFQRPNPFPTMSIRENVLAGIKLNRKRIHRIQQNELMERCLRSVNLWDEVHNRLGRPGGELSGGQQQRLCIARAIAVSPRVILMDEPCSALDPVSTKAIEQLICKLKEKHTIVIVTHNMQQASRVSDWTAVFNVARSGGSGELVEHDKTEVIFTSPKNEVTLNYISGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.