PharMolix/UniProtQA huggingface dataset:
Protein: RF2_STAHJ
Sequence: MELSEIKRNIDEYRNNLAQIRGSLDFENKETNIQEYEEMMTEPDFWDDQNKAQDVIDKNNALKSVVNGYHELEEEVEDMTATWELLQEELDGDVKSDLEQNVLDFKEKVDQFELQLLLDGPHDANNAILELHPGAGGTESQDWASMLLRMYQRYGEQQGFKVETVDYLPGDEAGVKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPEFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPTGIVVNNQNERSQIKNREAAMKMLKAKLYQLKLEEQEREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGEIGPFIESYLRYTMNQSDN
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_THISH
Sequence: MPELPEVETTRRGIERHVTGRRVTSVIVREPRLRWPVPGDLAERLTGHTLGRVLRRAKYLLIEVDTGLLLLHLGMSGSLRVVTPDAPLRKHDHIDLCLDSGRCLRLHDPRRFGAVLWIEGPAHAHPLLAELGPEPLGKDFDADYLFRSTRKRRVAIKQHIMNSHVVVGVGNIYASEALFLAGIRPGRAAGRLTRAECARLVETIRQVLGEAIAQGGTTLRDFVREDGSHGYFQQHLRVYGRTGLACMACETPVKQIVQGNRSTYYCPACQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RISB_SALTI
Sequence: MNIIKANVAAPDARVAITIARFNQFINDSLLDGAVDALTRIGQVKDDNITVVWVPGAYELPLATEALAKSGKYDAVVALGTVIRGGTAHFEYVAGGASNGLASVAQDSGVPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: CPG2_CAEBR
Sequence: MKTIVALGLLALATAASGQFLQDCTNALDGLYAIGNCESQFLTCSGGIARIMDCPADLIYNEPLLICDWRHNVVGCEGSGEASGEQSGEGSGEASGEGSGEASGEGSGEASGEGSGSGEGSGEENNVCEGLEDGAYSSGGCTTYYFFCTDNTARFLSCPTPLFYDVATQKCAWKALVEECNGEIIIDGSGETSGEGSGEASGENSGENSGEGSGEFEPTCDGKADGIYPNGVCVPNFLTCSGGIARVMNCPASLIFNPDILVCDWPRDVAECHGLSTPAPVCEDDGYFSFGQCSSSFTACTNGRAIVMFCPAGLKFSQANQRCDYDDLVNECQEASGEESSGEASGEQSGEGSGEASGEASGEASGENECVSLDNGLHAIGCSPRVLSCQNGHVDIFECPSSLVFNEQTLICDYPQTSLKCLIEDTLLIDETPITPFDCSTNGLFSDGLCSATYHQCSAGQLINFTCAETNAVFSAANAECVDSSTLLQCH
What is the function of this protein?
Required for polar body extrusion during cytokinesis in embryo development.  Affects cortical granule size.  Shown to have roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2.  Binds chitin (By similarity).
What are the official names of this protein?
Chondroitin proteoglycan 2.
Protein: Y2337_MYCBO
Sequence: MVAALHAGKAVTIAPQSMTLTTQQAADLLGVSRPTVVRLIKSGELAAERIGNRHRLVLDDVLAYREARRQRQYDALAESAMDIDADEDPEVICEQLREARRVVAARRRTERRRA
What are the official names of this protein?
Uncharacterized protein Mb2337.
Protein: YAY4_SCHPO
Sequence: MSQAIREATHAGSWYLDDTELLTKQLKSFIKNPTPETGKRFVISPHAGYMYSGKVASQGFQQLDFSKIQRVFVFGPSHHIFTRKCLVSRASICSTPLGDLKVDEDLCQKLVASDNSFDSMTLDVDESEHSLEMQFPLLAFHLLKQGCLGKVKIVPIMIGALTSTTMMAAAKFLSQYIKDESNSFVISSDFCHWGRRFGYTLYLNDTNQLEDAVLKYKRRGGPTSPKIYESISNLDHIGMKIIETKSSDDFSEYLKTTQNTICGRYPIELIMKSMECANFSERFKFISYAQSSHVELVTDSSVSYATATA
What are the official names of this protein?
MEMO1 family protein C4H3.04c.
What is the protein family that this protein belongs to?
Belongs to the MEMO1 family.
Protein: PANB_SACEN
Sequence: MTAAHDRSENQPGRPGGETTAPYGSAPRRRRVRTRHLLELKQRGEAWPMLTSYDMYTARIFDEAGIPVLLVGDSAANNVYGYDTTVPVTVEELIPLVRAVTRGARSALVVADLPFGSYEASPEQALATAVRFMKEGGAHAVKLEGGRPFARHVEALVNAGIPVMGHIGFTPQSEHTLGGYRVQGRGEQAEELAADARALQDAGAFAVVLEMVSSDSAKRVTAELTIPTVGIGAGPECDAQVLVWTDMAGMNTGRTARFVKRYADLGGTLARAAQEFADEVRGGAFPAPEHSFE
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSLU_RICFE
Sequence: MKATKTTYKKDPMGLTPSQIVNELNRFIVGQEKAKKAVAIALRNRCRRKRVEGNLRNEIVPKNILMIGSTGVGKTEIARRLAKLTNSPFYKIEATKFTEVGYVGRDVESIIRDLVEIAVNTKKTLAKMEVDINAREKAIERILDSLVGKTSSSETREKFKEKILNGKLDDTEIEISVADTTPVGGGSFEIPGMPGASMGVLNLGDMIGRALGSSKTKTKKMLVKDAMAIIIPEESEKLIDQEKIIQQAINLAENDGIVFIDEIDKIASTGSSGAKNAEISREGVQRDLLPLIEGTTVNTKYGPVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELNSLTKDDMIKILLEPETSLVKQYSALIGTEDVHLEFAASAIEKIADYAITVNLEVEDIGARRLHTILENLLEDISFEASEMKGKKITIDDKFVENQLSKIITNLDLAKFVL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTC_ECO55
Sequence: MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLVYAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFMAG_PESFW
Sequence: MSPSAIHNITSDLPSSQQHRPFAGKVALITGSGRGIGRGIALELGKRGASCIINYAKSAGAANEVVAELAKLGSKSIALQADISKPADVAALFEKALKHYGHIDFAISNSGMEVWCEETEVTPELFDQVFNLNTRGQFFVAQNALKHCSEGGRIILTSSIAAQMTGIPNHALYAGSKAAVEGFARSFAVDCGRKRITCNALAPGGIQTDMFDENSWHYVPGGYQGMNIDTIKDGLAKMCPLNRVGTPADIGKIVCMLVSDEGEWINGQVLRCSGGGV
What is the function of this protein?
Tetrahydroxynaphthalene reductase; part of the gene cluster that mediates the biosynthesis of dihydroxynaphthalene (DHN)-melanin, a bluish-green pigment forming a dark layer in the conidial wall that protects the conidia from UV radiations (PubMed:28517364).  The first step of the pathway is the production of the pentaketide 1,3,6,8-tetrahydroxynaphthalene (1,3,6,8-THN or T4HN) by the polyketide synthase PfmaE though condensation of acetyl-CoA with malonyl-CoA.  T4HN is not stable and easily oxidizes into the stable form flaviolin (PubMed:28517364).  T4HN is also substrate of the hydroxynaphthalene reductase PfmaG to yield scytalone (PubMed:28517364).  The scytalone dehydratase PfmaJ then reduces scytalone to 1,3,8-THN (PubMed:31116900).  1,3,8-THN is then substrate of the hydroxynaphthalene reductase PfmaI to yield vermelone (Probable).  Vermelone is further converted by the multicopper oxidase PfmaD to 1,8-DHN (Probable).  Finally the laccase PFICI_06862 transforms 1,8-DHN to DHN-melanin (Probable).  The roles of the 5-oxoprolinase PfmaA and the proline iminopeptidase PfmaB within the cluster have not been elucidated yet (Probable).
What are the official names of this protein?
Tetrahydroxynaphthalene reductase PfmaG, Conidial pigment biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: SYL_PSEPF
Sequence: MHEQYQPREIEAAAQSFWDEQKSFEVSEQPGKETYYCLSMFPYPSGKLHMGHVRNYTIGDVISRYQRMLGKNVLQPMGWDAFGMPAENAAMKNNVAPAKWTYENIAYMKSQLRSLGLAVDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDPIDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYADELLESLDELTGWPEQVKTMQRNWIGKSRGMEVQFPYNVDSIGESGTLKVFTTRPDTLMGATYVAVAAEHHLAALAAKNNPELQAFIAECKGGSVAEADVATQEKKGLPTGLFVEHPLTGEKLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNLPVKSVVRTSSGDTNPAPWQDAYGEHGTLINSGEFDGLDFAGAFDAMEVALIKKNLGASRTQFRLRDWGISRQRYWGCPIPIIHCDACGDVPVPEDQLPVVLPEDVVPDGAGSPLARMPEFYECTCPKCGQPAKRETDTMDTFVESSWYYARYASPHFEGGLVEKSAADHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGLVSSNEPFKNLLTQGMVVAETYYRREANGAYTWFNPADVELERDSKAKVISAKLIADGLPVEIGGTEKMAKSKNNGVDPQSMIDQFGADTCRLFMMFASPPDMSAEWSDSGVEGSHRFLKRVWRLAQAHITQGLPGKLDIASLNDEQKVIRRAIHQAIKQASHDVGQNHKFNTAIAQVMTLMNVLEKAAQATEQDRALVQEGLETVTLLLAPITPHISHELWNRLGHADPVIDASWPVLDESALVQDSLTLVIQVNGKLRGQIEMPAAATREEVEAAARANENVLRFVDGLTIRKVIVVPGKLVNIVAS
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURD_CHLPB
Sequence: MNAETTDGKRVSIIGAKRSGIAAALLLQQRGATVYVSDREPVGDAERAFLEHHGIAFEEEGHTDRILEADFSVVSPGIPPHASVIRRLEHEAIPLFSEIEAASWFCPAFIIGITGTDGKTTTSSMVEAICLSGANSREQRVFSAGNIGVPFSSLVGEMRKGDIAVVELSSYQLERCRSFRPDVAVITNIMPDHLDRYGGSMKRYAEAKYRIYAQQRKQDTLVYNADDETLRAHFEGGGAFVPQLVPFSLDRKRASLGGACYAAIEGDWLITVVNGREEKVITGSGLFKRSFRGRHNLENALAAVAATRAAGVDVFPIREALRRFAGVEHRQEYVRTMHGVDWINDSKATNLNALRQALDATPGKLVLIAGGRDKGDDLSDLEERVRQKVSVLVVFGESKAKFTEAFSSVVRVVPALSLEEAVEQAQRYASTGETVLFSPGCSSFDMFESFEERGMRFKKHVEGMQS
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OFUT2_PLAVS
Sequence: MKGRAHIWVALLLACLPPRFRNLDKDVSSPVCRTDDVYTGDAFYPFKKKKYVLYDVHIGEGFNLQKEVLYRVALAVYYLNQEERTHVHYLVLPPWCYVTHWGRERTNARIKWSIFFNLKALQNVIPVMEYAEYEGQFGPHTDYILSYRHIIGEWPKRGDKKSFQVLKLDKCQVKGYKLKKNLRKNCDHKYSVEYSGKCTNVKGKKMECLEFFFITSHFVSSTLLDIFQYDADSVLIKHGSNILVAFMNELVDANLEDVLPYSEDLINEGDQFVEKNFKSSKNYISCHLRYTDFRKISTYDVSPVGISLLKLLYIMFLRKSTLIFVSTDEKKEVKKVIDSQFPQFKHFFFFYENEKLHTGQVAIVDQWICARSGTFVGNIFSRFSMHIKWERSLIGKGGPDHNLDLCGYSISTNHELRKKYSDVQDAHLDEEALQKLRPLYMRLSQKDRDFLRTICYDFAHYYPQNVSIYRRGERREEGRLM
What is the function of this protein?
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X-X-S/T-C2 of thrombospondin type I repeats (TSRs) where C1 and C2 are the first and second cysteines of the repeat, respectively (PubMed:28916755).  O-fucosylates sporozoite proteins CSP and TRAP (PubMed:28916755).  O-fucosylation regulates stability and intracellular trafficking of TRAP but not of CSP (By similarity).  Probably by regulating protein O-fucosylation, may play a role in parasite transmission to the mosquito vector and/or infection of the vertebrate host hepatocytes; however, POFUT2 involvement in transmission/infection is controversial (By similarity).
What are the official names of this protein?
GDP-fucose protein O-fucosyltransferase 2, Protein O-fucosyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 68 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: HRPW_PSESY
Sequence: MLALFLGSLSLIPFLLIVCTAFLKIAMTLLITRNAIGVQQVPPNMALYGIALAATMFVMAPVAHDIQQRVHEHPLELSNADKLQSSLKVVIEPLQRFMTRNTDPDVVAHLLENTQRMWPKEMADQANKNDLLLAIPAFVLSELQAGFEIGFLIYIPFIVIDLIVSNLLLALGMQMVSPMTLSLPLKLLLFVLVSGWSRLLDSLFYSYM
What is the function of this protein?
Required for the secretion of harpin.
What are the official names of this protein?
Harpin secretion protein HrpW.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF11_NOVAD
Sequence: MAKEELLEMRGTVVELLPNAMFRVRLENDHEILGHTAGKMRKNRIRVLVGDEVLVELTPYDLTKGRITYRFMPGRGGPGGF
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT32_MOUSE
Sequence: MGVTGISTFPCCGKDSVDIVERQSDHHRHHHHHTHEENEDEDTEVEAELPRTEPPPKVDPELGPVPQLEEMEPELPSKTTPETEGDSYTESPEQQNYRMESLKPYEEEEMGGRYRSIPVQTSKHLFWSNKLIQASEHSLQKALEKHHRSPQEKSISISQVYTECTQPPSSPPVSRPTTPTAIGLADLINFASSLAVASSSNMALPNLENMIKGTSEKSQNTSLDFCQPVQAIKFAQATQITQISSEKQDESPKSMAHKSWTRETRNVACSYLDINQAGLKTATIQGEVKFVQTPIASPQLQEAKEDSVPGTKKGNPLLLKIHFKLSSPQPQRND
What are the official names of this protein?
Spermatogenesis-associated protein 32, Acrosome expressed protein 2.
Protein: SYD_THEVO
Sequence: MPRVYIGSLRELNHNDNVEIYGWLQDLKLLKNVSFLIMRDRTGTVQVTFKNTPDIVNLLKELPRESVLKISGKINKKSVSKSGLEVSGESVEVLNRSERPLPLPVIDPVQADLETRLNNRFIDLRKRDVSSIFNAESSILWGIREFLHSQGFIEVHTPKIVAAATEGGADLFPVKYFENDAYLNQSPQLYKEILMSSGFEKVFEVGPAFRAEEHNTTRHLNEFTSIDIEMSFADHNDAMRILENAVKSGIENMINENGKDLQENGINISIPEIPFPRITYKECIKLLEKEGLEFQFGNDFSPEELRIIGRNFKDFYFITEWPSSLRPFYTMPNRDDPTITNSFDLQYREVEVTSGAQRVHDPDLLLKRFNEKKLNIDSFKFYIQAFKYGMPPHAGWGLGLERLTMIVLGLNNIRETTLFPRDRTRIIP
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA(Asp) ligase, Aspartyl-tRNA synthetase, AspRS, Discriminating aspartyl-tRNA synthetase, D-AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRMA_HAEIN
Sequence: MEIKQINSTIKSRAAVAFAPNQPLQIVEIDVEMPRKGEVLIRNTHTGVCHTDAFTLSGSDPEGVFPVVLGHEGAGVVVAVGEGVLSVKPGDHVIPLYTAECGECEFCRSGKTNLCVSVRDTQGKGLMPDCTTRFSYQGQPIYHYMGCSTFSEYSVVAEVSLAKINPEANHEQVCLLGCGVTTGIGAVHNTAKVQEGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPAKFELAKQFGATDCLNPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRQALESAHRGWGQSIIIGVAGAGQEISTRPFQLVTGRVWKGSAFGGVKGRSELPQMVEDSMKGDIQLEPFVTHTMPLDKINEAFELMHEGKSIRTVIHY
What are the official names of this protein?
S-(hydroxymethyl)glutathione dehydrogenase, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NANE_SHIB3
Sequence: MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
What is the function of this protein?
Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).
What are the official names of this protein?
Putative N-acetylmannosamine-6-phosphate 2-epimerase, ManNAc-6-P epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanE family.
Protein: Y3874_MYCTU
Sequence: MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSIPPNLFVSAQRATS
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Rv3767c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: NELFA_DROME
Sequence: MANVRDSDTSLWLHNKLGTSNDSWINGSICSQLNKEVLRNIKECFPDLQTQVKLKLLLSFLHIPRRLVEEWKAELEEVIEVAGLDSELWVSMLAETMKTFPATSSLNTEISDYEDTRPIFIDMVNDLRKLVTKHSDLGMLPLECQYLNKNALISVVGQQPAPVKHFTLKRKPKSAQLRTELLHKSADAQSSLKKASAPTIPLRSRGMPRKMTDTTPLKGIPSRMPTTGFRSATVPGNAAQRPNLSRTPAGRKDGGIKLIEFTEQPLGYAAAKKRKREQQLEEQQKKQEQKQQQAAAAAAAAATAAASNAGDSSPTDAATASGGETPVTPTSANNSFEIKMEPQQLNQSAGSLEEPQDDEMSGKANMECDIETPEYATATLDFAQATSTSVADGQPGKPAVETKLKTPRTPKSAAKLNNNNNNNNNNSFNHTPKRIKQEIEIKSEEIIVPASIKLEKIETSPSTQRVSIQQQPPSLVQRTPHLLIRSSPQKRQNNGATTSAGTTTTTVGNTTIKMEKLDIKPMIRATGVSPSTSAGTTTTLLTPQQLRQAANPLANLPNNISVKITSAKAKAAAAAAATSSGSQTQSQQPQTLQVQQAPQQSHPPLLINSSTPVILASSPSAQRAKALALPSSSTSATTTTTIPSQAIKTMPLSQLKTATNSGPVIISQTIIQPAKRAQQQAGTSSAAAASQQQQQQQSQQQLLHQQIQQQTQQQAQLPQQPQQQQTQYILATPQQQPQQIQQQQQQQQPILPTLTSFSHSRPMPQTTTLYQATTPSGSGQTPTKILLKTSGSSSVVMTPLRQAQPQQATAVVSSNPPPLVATSAAVVSPGQTTLNIQNVQLPNRPVTIQPASQAAQQQHMQAQLQQQQPHPQHTIVANTTATQQPKLSQVLMQPTAAVGTSGVSALNVSPTSGKNKTIILTQKGVILRNIGGDMYQQIPISNVGNMQGLGGTTLMTTTAGPPSLVKTTPSSGVQLQQQQSGKQILPTLIPTSSLGGQHVIVQQQQPTNVIGNSQQQTIIRPVMTNVGGGLTTLPQGLTLIQRPGQQPQLVQVQAAPGSTQRTIITQSNTAAAASQQQPRQQQQQILVQHKPAPTLQQRLVTSTTSGGQGQQGNPNAGLPRTVQVQVQAQQQQQPQQQQATQQQSQQAPQRRGLSLSNEHVHKAHEMFRKANRVSRPDKALILGFMAGLRENPRPNNENVLVIKLGETEEKVQQDNGHTALCLVESHIRLDYNTGEWKTFQNYRLQDQSAAS
What is the function of this protein?
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II.  Has an essential role in postembryonic development.
What are the official names of this protein?
Negative elongation factor A.
What is the protein family that this protein belongs to?
Belongs to the NELF-A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with polytene chromosomes. Associates with the hsp70 promoter when it is inactive, but not when it is activated.
Protein: FOX2_NEUCR
Sequence: MAEQLRFDGQVVVVTGAGGGLGKAYCLFFGSRGASVVVNDLGASFKGEGNSTKAADVVVNEIKAAGGKAVANYDSVENGDKIIETAIKEFGRIDILINNAGILRDISFKNMKDEDWDLIFKVHVKGSYKTARAAWPYFRKQKFGRVINTASAAGLFGNFGQANYSAAKLGMVGFTETLAKEGLKYNIISNVIAPIAASRMTETVMPPDLLALMKPEWVVPLVAVLVHKNNTSETGSIFEVGGGHVAKLRWERSSGLLLKADESYTPGAIIKKWDQVTDFSNPQYPTGPNDFLALLEESLKLGPNDPGEKVDFKGRVALVTGGGAGIGRAYCLAFARAGASVVVNDLVNPDDVVNEIKKMGGKAVGAKFSAEDGDAVVKAAIDAFGRVDIVVNNAGILRDKAFHNMDDSLWDPVMNVHARGTYKVTKAAWPYFLKQKYGRVLNTTSTSGIYGNFGQANYSAAKCAILGFSRAIALEGAKYNIYVNTIAPNAGTAMTKTILPEELVQAFKPDYVAPLVLALCSDKVPKKPTGGLYEVGSGWCGQTRWQRSGGHGFPVDVPLTPEEVVKHWNDIVTFDSRADHPEKASDSIEKIMANMENRVGEGKSGAAENEHLAAIKKFTGVEGKGTEYTFTERDVCLYNLGIGAKRTDIKYIFEGNEDFEVVPTFGVIPPFNTEMPFSFDDIVPNFSPMMLLHGEQYLEVRKYPIPTSGRLVSKGKLLEVVDKGSAAIVKQGITTFNAETGEELFYNEMTVFLRGCGGFGGQKKPADRGASTAANKPPARSPDAVVEVQTTEEQAAIYRLSGDYNPLHVDPAFAKVGGFKVPILHGLCSFGIAGKAVYEKYGKFKNIKVRFAGTVNPGQTLVTEMWKEGNKVVFQTKVKETGKLAISGAAAELA
What is the function of this protein?
Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase-epimerase activities.  Converts trans-2-enoyl-CoA via D-3-hydroxyacyl-CoA to 3-ketoacyl-CoA.
What are the official names of this protein?
Peroxisomal hydratase-dehydrogenase-epimerase, HDE, Multifunctional beta-oxidation protein, MFP.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Peroxisome. Note=Catalase-free microbodies.
Protein: NANT_SALSV
Sequence: MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLACGFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIINILMTFAAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPTGVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKN
What is the function of this protein?
Catalyzes the proton-dependent transport of sialic acid.
What are the official names of this protein?
Sialic acid transporter NanT, Sialic acid permease, Sialic acid/H(+) symporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CA13_CONBN
Sequence: MGMRMMFTVFLLVVLATAVLPVTLDRASDGRNAAANAKTPRLIAPFIRDYCCHRGPCMVWCG
What is the function of this protein?
Does not show activity on the acetylcholine receptors tested.
What are the official names of this protein?
Alpha-conotoxin-like Bn1.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_LEGPA
Sequence: MGKISLMLRQIVCLPIKMYQYFISPLITPCCRYYPSCSEYADSAIKHYGVIKGLLMALNRLSRCHPWSKGGYDPLFPNDKN
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RAB7A_DICDI
Sequence: MATKKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKELMVDDRVVTMQIWDTAGQERFQSLGVAFYRGADCCVLCYDVNVAKTFENLDSWRDEFLIQAGPRDPDNFPFVVLGNKIDLENQRVVSQKRAASWCQSKGNIPYFETSAKEAINVEQAFQTIARNAIKLEDGLVFPIPTNIQVIPEPQPAKSGCC
What is the function of this protein?
Small GTPase which cycles between active GTP-bound and inactive GDP-bound states.  In its active state, binds to a variety of effector proteins playing a key role in the regulation of endo-lysosomal trafficking.  Governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity).  Involved in lipophagy, a cytosolic lipase-independent autophagic pathway (By similarity).
What are the official names of this protein?
Ras-related protein Rab-7a.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Late endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lysosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet. Cytoplasmic vesicle.