PharMolix/UniProtQA huggingface dataset:
Protein: SSRP_CLOB8
Sequence: MARKRNENSLAENRKARHDYFVEEAMEAGLVLVGTEVKSIRNGRVNLKDCYADIYNGEIFVKNMHISPYEQGNIFNVDPLRERKLLLHRDEIRRLDGLVSRDGYTLIPLSLYLKDGKVKVALGVCKGKKNYDKRDSMLEKAHKRDMDRAIKEKNKY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SYDP_ECO7I
Sequence: MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGTRKRTHLASNLAEFLNQLKPLL
What is the function of this protein?
Interacts with the SecY protein in vivo.  May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function.
What are the official names of this protein?
Protein Syd.
What is the protein family that this protein belongs to?
Belongs to the Syd family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Note=Loosely associated with the cytoplasmic side of the inner membrane, probably via SecY.
Protein: SYE_SACS2
Sequence: MMELNELRETIYKYALQNAVKHNGKAETGPVMSKIIAERPELRSNAREIVKIIKEIIEQVNSLTLEQQLTEIKAKYPELLEEKKHEEKRKVLPPLPNVKGQVVTRFAPNPDGPLHLGNARSAILSYEYAKMYNGKFILRFDDTDPKVKRPILDAYDWIKEDLKWLGIKWEQELYASERLELYYKYARYLIEKGYAYVDTCDSSIFRKFRDSRGKMKEPECLHRSSSPESNLELFEKMLGGKFKEGEAVVRLKTDLSDPDPSQIDWVMLRIIDTAKNPHPRVGSKYWVWPTYNFASIIDDHELGITHVLRAKEHMSNTEKQRYISEYMGWEFPEVLQFGRLRLEGFMMSKSKIRGMLEKGTNRDDPRLPTLAGLRRRGILPDTIKDVIIDVGVKVTDATISFENIAAINRKKLDPVAKRIMFVKDAEEFSVELPESLNAKIPLIPSKQEMNRTIIVNPGDKILIESNDAEDNSILRLMELCNVKVDKHNRKLIFHSKTLDEAKKVNAKIVQWVKSNEKVPVMVEKAERDEIKMINGYAEKIAADLEIDEIVQFYRFGFVRVDRKDENMLRVVFSHD
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y032_HIS1I
Sequence: MTADRQWVKIIARWLARIDGISGMLRLAMLGLTGVSTMSFTLKDYGLERLVWPLIGAMCVGTLLFAYYYTEGGVWNQVHRDKRDMSQNYATPFQKISNEMTARGLYAGEKGSELSQEERQAIQKEIDMAYMELRDGIEVEKDD
What are the official names of this protein?
Putative transmembrane protein ORF32.
What are the subcellular locations of this protein?
Host membrane; Multi-pass membrane protein.
Protein: YIDD_SYNS9
Sequence: MHESPILSNGDQPNRWAGLNRRVAALLLALIGFYRTFISPLLGPRCRFTPTCSAYGLEAIQRHGPWRGGWLTLKRVLRCHPFTPCGCDPVPD
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YPZ3_METTF
Sequence: MKKLNNIIMILIMHRYFLRVMNLRQKVIEALEEGKSVAIKYQDVRDYLDLKTGHRVIFLEHINPAKETAAEILADLGNLAKSTIYSKYTTNEIVRDIKKRSKNRNVLLVFNDFQLLSKNTARVLLDLMEDVQVLCSIRGRPQKGQGRLLKRMTILSDRSDEVTDIKIPLIVFASFIAILTFVKAGSAIYNRNHFDFYLFSAAIFVGISVGRTLLWIS
What are the official names of this protein?
Uncharacterized protein ORF3'.
Protein: TX820_LYCSI
Sequence: MKLIIFTGLILFPIVSLIEAQAKNEKACLPQYQVCTDAPGNCCSNLICDCYGRYKNGARIGRNCFCLQKGVLYKKEN
What are the official names of this protein?
U8-lycotoxin-Ls1k, Toxin-like structure LSTX-H20.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 19 (CSTX) family. 08 (U8-Lctx) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CTPG_MYCTO
Sequence: MTTVVDAEVQLTVVSDAAGRMRVQATGFQFDAGRAVAIEDTVGKVAGVQAVHAYPRTASIVIWYSRAICDTAAILSAIIDAETVPAAAVPAYASRSASNRKAGVVQKIIDWSTRTLSGVRRDVAAQPSGETSDACCDGEDNEDREPEQLWQVAKLRRAAFSGVLLTASLVAAWAYPLWPVVLGLKALALAVGASTFVPSSLKRLAEGRVGVGTLMTIAALGAVALGELGEAATLAFLFSISEGLEEYATARTRRGLRALLSLVPDQATVLREGTETIVASTELHVGDQMIVKPGERLATDGIIRAGRTALDVSAITGESVPVEVGPGDEVFAGSINGLGVLQVGVTATAANNSLARIVHIVEAEQVRKGASQRLADCIARPLVPSIMIAAALIAGTGSVLGNPLVWIERALVVLVAAAPCALAIAVPVTVVASIGAASRLGVLIKGGAALETLGTIRAVALDKTGTLTANRPVVIDVATTNGATREEVLAVAAALEARSEHPLAVAVLAATQATTAASDVQAVPGAGLIGRLDGRVVRLGRPGWLDAAELADHVACMQQAGATAVLVERDQQLLGAIAVRDELRPEAAEVVAGLRTGGYQVTMLTGDNHATAAALAAQAGIEQVHAELRPEDKAHLVAQLRARQPTAMVGDGVNDAPALAAADLGIAMGAMGTDVAIETADVALMGQDLRHLPQALDHARRSRQIMVQNVGLSLSIITVLMPLALFGILGLAAVVLVHEFTEVIVIANGVRAGRIKPLAGPPKTPDRTIPG
What are the official names of this protein?
Probable cation-transporting ATPase G.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TRI25_HUMAN
Sequence: MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSICSPK
What is the function of this protein?
Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase (PubMed:16352599).  Involved in innate immune defense against viruses by mediating ubiquitination of RIGI and IFIH1 (PubMed:17392790, PubMed:30193849, PubMed:33849980).  Mediates 'Lys-63'-linked polyubiquitination of the RIGI N-terminal CARD-like region and may play a role in signal transduction that leads to the production of interferons in response to viral infection (PubMed:17392790, PubMed:23950712).  Mediates 'Lys-63'-linked polyubiquitination of IFIH1 (PubMed:30193849).  Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway (PubMed:16352599, PubMed:17069755).  Mediates estrogen action in various target organs (PubMed:22452784).  Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).  Plays a role in promoting the restart of stalled replication forks via interaction with the KHDC3L-OOEP scaffold and subsequent ubiquitination of BLM, resulting in the recruitment and retainment of BLM at DNA replication forks (By similarity).  Plays an essential role in the antiviral activity of ZAP/ZC3HAV1; an antiviral protein which inhibits the replication of certain viruses.  Mechanistically, mediates 'Lys-63'-linked polyubiquitination of ZAP/ZC3HAV1 that is required for its optimal binding to target mRNA (PubMed:28202764, PubMed:28060952).  Mediates also the ubiquitination of various substrates implicated in stress granule formation, nonsense-mediated mRNA decay, nucleoside synthesis and mRNA translation and stability (PubMed:36067236).
What are the official names of this protein?
E3 ubiquitin/ISG15 ligase TRIM25, Estrogen-responsive finger protein, RING finger protein 147, RING-type E3 ubiquitin transferase, RING-type E3 ubiquitin transferase TRIM25, Tripartite motif-containing protein 25, Ubiquitin/ISG15-conjugating enzyme TRIM25, Zinc finger protein 147.
Protein: DNM1A_ORYSJ
Sequence: MAKSPRSVVTTGTKRRRAKVHKEDEPVENENLESEFDVSKKESNGATEPGNEPVASKRPKRAAACSNFKEKSLDLSEKDSIITIKESRVEEKEIEAVNLTRTGPEDGQPCRKIIDFILHDGDGNLQPFEMSEVDDIFITALIMPLDDDLEKDRGKGICCSGFGRIENWAISGYDEGAAVIWVSTETSDYKCVKPASSYRSYFEHFSEKARVCVEVYKKLARSVGGNPQVDLEELIAGVVRSINSNRSFNGTVTKDFVISSGEFIYKQLIGLDHTAGNDDEMLATLPVLVALKDECKSRAGFTHLPAMPSNGTLRIKDGQDKGLTEDEDAKLARLLQEEEEWKMMKQRGKRGTSQKNIYIKICETEIANDYPLPAYYKPYNQEMDEYIFDSDIGMYSDDVPVRILDNWALYNSDSRLISLELIPMKAGAENDIVVFGSGFMREDDGSCCSTAELAQLHSSSSKSGREDPGVPIYLSPIKEWVVEFGGSMICITIRTDVAWYKLRQPTKQYAPWCEPVLKTARLAVSIITLLKEQSRASKLSFAEVIKKVAEFDSRHPAFISSKAPTVERYVVVHGQIILQQFADFPDESVKRCAFITGLLAKMEESRHTKLAIKKKSQQMRGENLNPSAKMGPILRKKLMRATTTMLISKIWGEYYATYFPGDTKEEDQNEPKEIDDDQEENEDNDAEEEVNVQDEKATRTPPSTRSRKSSADTRKEIKWEGQTAGKTVSGEVLYKCVIVQDLSISVGATVTTEDDSGETIMCFVEYMYEKLDGKNMIHGIILQEGSQTVLGNAANDREVFLTNDCLEFEASDIKELVTVNIQSLPWGHKYRKENSEAKRIEKAKAEERKRKGLPVEYICKSLYWPEKGGFFSLPYDKIGNGTGICSSCERKPVGNEFKLLSESSFVFENITYNIHDFLYIRPEFFSQGEGHETYKAGRNVGLKPYAVCHLLSVHGPAGSRKANPESTKVKVRRFYRPDDISSTKAYSSDIREVYYSEDIISVPVVMIEGKCEVRLKDDLPNSDLPAVVEHVFCCEYLYDPANGALKQLPPNVRLVTLTRKVPASKKNKGKQICDIELGGSDKPKDGQSENCLATLDIFAGCGGLSEGLQRSGLSLTKWAIEYEEPAGDAFGENHPEAAVFVENCNVILKAIMDKCGDSDDCISTSEAAERAAKLSEDKIKNLPVPGEVEFINGGPPCQGFSGMNRFNQSPWSKVQCEMILAFLSFAEYFRPRFFLLENVRNFVSFNKGQTFRLTLASLLEMGYQVRFGILEAGAYGVAQSRKRAFIWAAAPGETLPEWPEPMHVFASPELKITLPDGKFYAAVKSTAAGAPFRSITVRDTIGDLPAVENGAGKPTIQYGSGPVSWFQKKIRSDMASLNDHISKEMNELNLIRCKHIPKRPGCDWHDLPDEKVKLSTGQMVDLIPWCLPNTAKRHNQWKGLYGRLDWEGNFPTSVTDPQPMGKVGMCFHPEQDRIITVRECARSQGFPDSYRFAGNIQNKHRQIGNAVPPPLAYALGRKLKQAIDAKR
What is the function of this protein?
Probably methylates CpG residues and maintains DNA methylation (PubMed:14513380, PubMed:24535433).  May be involved in methylation-dependent gene silencing (PubMed:14513380).  May play a minor role in the maintenance of DNA methylation (PubMed:24535433).
What are the official names of this protein?
DNA (cytosine-5)-methyltransferase 1A, OsMET1a, DNA methyltransferase 1-1, OsMET1-1.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SLYX_PSE14
Sequence: MSLEERVMELESRMAFQDDTIQALNDVLVKQRREFDHLQQQMAAMIKRQEEMGSQFDTFEEEAPPPHY
What are the official names of this protein?
Protein SlyX homolog.
What is the protein family that this protein belongs to?
Belongs to the SlyX family.
Protein: RL20_RICRO
Sequence: MTRAKSGKISKNRHKKILKLAKGYRGRANSCFRVAIEKVEKALQYAYRDRRNRKRDFRGLWIQRINAAVREHGLVYSQFMGALKKTEIAIDRKVLAELAVNNSDGFVSIVEKAKAHI
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: GCS2_SHIBS
Sequence: MPLPDFHVSEPFTLGIELEMLVVNPPGYDLSQDSSILIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQVTVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: ISPD_PHOPR
Sequence: MTQQLTAVVPAAGIGSRMAADRPKQYLHIAGKTILEHTIDRLFSHPAITRVIIAISQTDPYFASLPLANDPRITVVDGGAERADSVFAGLAAIDDENTWVLVHDAARPCVRLNDLERLVEAAIRSDSGAILAAPVRDTMKRGCQQINGLQGIVSTVDRNNLWHALTPQMFKVKQLKDSLQHALKEGAVITDEASALEYCGYIPQLVKGRSDNLKVTQPEDLALAGFYLEQLMKE
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: Y1121_AQUAE
Sequence: MFGKPEGKPKGLNWLYRDTYIGKRKGITLGFSFAMQNDIDQELISDTQGPAPGINGQGKPSPGAGSVQVRVPYMILPNPITTPEVRNHPVDMRMYGADLAIHYGPLSFILEAGQHQFKNVFLDAQKLSEDFKNNWFIIKGAYALNPKSTTVFEPYVSYYIWDPDIKEDSKGRAYGDAANFIKGNKAGKEKATLGKISVTSLGVNIWYTKAKLMSLTFEYQIINEERNEITPLPFNSALSFSRHLPLIFLRFCSQSFPNSSPYLKYCPF
What are the official names of this protein?
Uncharacterized protein aq_1121.
Protein: CALX_PEA
Sequence: MVDRKEIPLAMGLLAVLLFFVASSSSFHLVRASDEVDDAIFYESFDEDFDNRWIVSGKEEYNGVWKHSKSEGHDDFGLLVSEPARKYAIVKELDAPVSLKDGTVVLQFETRLQNGLECGGAYIKYLQTQESGWKPKGFDNESGYSIMFGPDRCGATNKVHFIFRHKNPKTGKHVEHHLKFPPSVPSDKLSHVYTAVLKDDNEVSILIDGEEKKKANFLSSEDFEPALIPSKTIPDPDDKKPEDWDERAKIPDPEAVKPEDWDEDAPREIIDEEAEKPEPWLDHEPEVDDPEAKPEDWDDEEDGEWEAPKIENPKCEAAPGCGEWKRPTKSNPAYKGKWSAPYIDNPNYKGIWKPQEIPNPEYFELEKPDFEPIAAIGIEIWTMQDGILFDNVLIAKDDKIAESYRETTWKPKFNIEKEKQKHEEEAAAAAAARSESEGIAGIQKKAFDLLYKIADIAFLSGQKEKIIEIIEKGEKQPNLTIGIIVSVVIVFVSIFFRLIFGGKKPANVEANVEKKKTNTETTSKQDGGEKEDNKEKEETANPPRRRPKRDN
What is the function of this protein?
Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum.  It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits.  It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity).
What are the official names of this protein?
Calnexin homolog.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: ENPP_APLCA
Sequence: MAKHDVTVMTLLLVVCALHVFDAQGTDVKLNDGFLRSGIMNIPFQRRVSPKYGHNFVGKRSGFQSPVSPSDYFIPDELNDEDESPNMDTYALFRELLGEYPSSELSDDDVIRPYPVVPWAWDRFENKRFSKENEKRGSPGFSHSFVGKRMDLSALEKELIAKLKAADLLSPLETEAPGKRRLPSYGHSFLGKRMPVDVFPRAIPSYSHNFVGKRSGNGENYFDDLDTFGDISQRADLGFTHSFVGKRGNTDFSRNPLARLSQVQNRAIPNFVHKFVGKRSVHNIVKRSSPFYGHNFVGKRDFEDASEGLDEEEGDIDGYSDDLDVKRVPGYSHSFVGKRIPGYSHSFVGKRTPGYSHSFVGKRVPGYSHSFVGKRVPGYSHSFVGKRVPGYSHSFVGKRVPGYSHSFVGKRVPGYSHSFVGKRTPGYSHSFVGKRAPGYSHSFVGKRTPGYSHSFVGKRAPGYSHSFVGKRAPGYSHSFVGKRAPGYSHSFVGKRVPGYSHSFVGKRAPGYSHSFVGKRVPGYSHSFVGKRAPGYSHSFVGKRELGEDEINFLKEVDAADISRQLAEEDEKEAMVSVDDKETLSNEEDASEDDFEKRELNFQHAFVGKKDEEGDMGVEMEEEMESEKGQPGYGNAFLGKRQPSYGHSFVGKRQPGYSHSFVGKRVPSFGHSFVGKRQPSYTHAFVGKRDPGFNHAFVGKRQPSFGHSFVGKRQPSFTHAFVGKRQPSFGHSFVGKRSGAEDIDNTFTDNFVVKGSDPLEDVLDFYSDSQLIGQPAAANEEELQQEAAEESENQTGTKQLDDKSNVPASSLGDDLPSPVSLSKQEDAEDSHIMATSST
What is the function of this protein?
Reduce interneurons B4/5 activity.  May play a regulatory role in nonfeeding behaviors.
What are the official names of this protein?
Enterin neuropeptides.
What are the subcellular locations of this protein?
Secreted.
Protein: SECG_STAAR
Sequence: MHTFLIVLLIIDCIALITVVLLQEGKSSGFSGAISGGAEQLFGKQKQRGVDLFLNRLTIILSILFFVLMICISYLGM
What is the function of this protein?
Involved in protein export.  Participates in an early event of protein translocation (By similarity).
What are the official names of this protein?
Probable protein-export membrane protein SecG.
What is the protein family that this protein belongs to?
Belongs to the SecG family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RSMG_NOSS1
Sequence: MTNLLPEMAEIWQQTLNWQPTDSQQARFQQLYELILEGNRQLNLTRITEPQEFWEKHLWDSLRGVAPQQQLISSLQLGASVIDIGTGAGFPGVPVAIIASNSTITLVDSTRKKITFIDTILSELALTNAKTLVSRAEEIGQQPQHREQYDVALIRAVGTASPCAEYTLPLLKLGGLAVIYRGTWTEEETTSVENAAQQLGGTVELIDNFTTPLTNSVRHCLYLRKVAKTPANFPRAVGVPSQKPI
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_CORK4
Sequence: MADTVTSARATARYVRVTPMKARRVIDTVRGKSVEEALDILKYAPQSASEPVYKVVASAAANAENNFGLDRNSLVIAQAWADEGPTMRRFRPRAQGRAFHVRKRTSHITVVVESQKGSAQ
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PAL_SHIFL
Sequence: MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMDANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYKVTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDEAAYSKNRRAVLVY
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Peptidoglycan-associated lipoprotein, PAL.
What is the protein family that this protein belongs to?
Belongs to the Pal lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: HVM57_MOUSE
Sequence: EVQLVESGGGLVKPGGSLKLSCAASGFTFSDYYMYWVRQTPEKRLEWVATISDGGSYTYYPDSVKGRFTISRDNAKNNLYLQMSSLKSEDTAMYYCAR
What are the official names of this protein?
Ig heavy chain V region 6.96.
Protein: HEPC_LARCR
Sequence: MKTFSVAVAVAVVLAFICLQESSAVPANEEQELEQQIYFADPEMPVESCKMPYYMRENRQGSPARCRFCCRCCPRMRGCGICCRF
What is the function of this protein?
Has very strong antibacterial activity against the marine Gram-negative bacteria V. alginolyticus (MIC=24 uM), V. fluvialis, V. harveyis (MIC=12 uM) and V. parahaemolyticus (MIC=6 uM).  Has antibacterial activity against the Gram-negative bacteria A. hydrophila (MIC=6 uM), E. coli (MIC=24 uM), and E. coli BL21(DE3)plysS (MIC=6 uM), and the Gram-positive bacteria B. cereus (MIC=24 uM), B. subtilis (MIC=6 uM), C. glutamicum (MIC=3 uM), M. luteus (MIC=3 uM), M. lysodeikticus, S. aureus (MIC=6 uM) and S. epidermis (MIC=12 uM).  Possesses antifungal activity against A. niger (MIC=24 uM), F. graminearum (MIC24 uM) and F. solani (MIC=24 uM), but lacks antifungal activity against the yeasts P. pastoris GS115 and C. albicans.
What are the official names of this protein?
Hepcidin.
What is the protein family that this protein belongs to?
Belongs to the hepcidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: SEY1_PLACH
Sequence: MANASKTQIIDYEGHIIDDLKEWMSDNGLSKLGFNYNVIAILGSQSSGKSTLLNNLFKTSFEVMNTKLGHSQTTQGLWLSYDKFEDELAGGSSEGTDAESKNKSGDKPVVNPTLILDVEGNDSKERGENRLTFEHRSALFSLALADCVIVNLWYHSLGNFTASNYGLLKTVMEVHLELFHQNVNCPKTILMFTVRDWFEEFAPLDVIREKIIEEYVNKIWQELKKPKSSKNAKVDDYFIIEVVGLSHGIIKKDEFLKDIKRLRHRWVYELRPVNYSRNIPADGFAQYCHNIWNTIVKQSQLDIPSQQEMLATFRCQEIKNNVLNSISGMIKEKIIDSKNRYIENFKTWAETDIIEKSVNEYLIDASRYQRSICLKTLEELLEAIFIQLQTIVDNNLNYTQRILSSKFSKELNSMYSVCTTDKGYFLLSSDKNADATEQDDNLSNMDKSGESAKKGNQSKCINLWSNFLYNADMLEYTTISNFYDQYKKCTIEIVEGSMASNESKDSQEKKNHDFNYKNSLTILATSIYKDTNRIRSVQCNILIERIRATIKEELKNVDNMLVTVKCSKDYWDYILKVTNKLEDYIYTNLSKCFVNLKIGINTTHLNNGDNIYARLNTNSDYGFVYSHNDHMYDFSDDENNNFDEIDTEIDQSKNDMESLFNSKKFEIITKQNKKEKYVSSINNDLTKEMNNKKLILELKNFYIEIIIDALKIKLDEISNDIANVIINRFESVFNYDEIEQPRQWRNVSVVELKNIFRVSKDYAFLIVEILQKNIKIDKLDKHLPNNFINTDIIEKGKSKAKKRIQEICRDAQYIQETGGQMSLKNVPFAFWVILLILGWNEILMFTRLFFRLNIILPMFMAFIIIVGSCLYTGNAQVLSYLNKIAFIVIKHSYNFYKHLQTVGNQPTKPEKVD
What is the function of this protein?
Probable GTP-binding protein involved in generating and maintaining the structure of the tubular endoplasmic reticulum network.
What are the official names of this protein?
Protein SEY1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LSM4_YEAST
Sequence: MLPLYLLTNAKGQQMQIELKNGEIIQGILTNVDNWMNLTLSNVTEYSEESAINSEDNAESSKAVKLNEIYIRGTFIKFIKLQDNIIDKVKQQINSNNNSNSNGPGHKRYYNNRDSNNNRGNYNRRNNNNGNSNRRPYSQNRQYNNSNSSNINNSINSINSNNQNMNNGLGGSVQHHFNSSSPQKVEF
What is the function of this protein?
Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner.  Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation by activating the decapping step.  Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs.  LSM2-LSM8 associates with multiple spliceosome snRNP complexes containing the U6 snRNA (U4/U6 snRNP, U4/U6. U5 snRNP, and free U6 snRNP).  It binds directly to the U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes.  It probably also is involved in degradation of nuclear pre-mRNA by targeting them for decapping.  LSM4 binds specifically to the 3'-terminal U-tract of U6 snRNA.  LSM2-LSM8 probably is involved in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.  LSM4, probably in a complex that contains LSM2-LSM7 but not LSM1 or LSM8, associates with the precursor of the RNA component of RNase P (pre-P RNA) and may be involved in maturing pre-P RNA.  LSM4 is required for processing of pre-tRNAs, pre-rRNAs and U3 snoRNA.
What are the official names of this protein?
U6 snRNA-associated Sm-like protein LSm4, Like-SM protein 4.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FABP6_CAEEL
Sequence: MSQEFVGRWKLIHSENFEEYMKEVGVGLITRKAAANLKPTLEIKVEGDLWYSNQYSTFKNTTLSFKLGQEFDETTPDGRTVKSVVNFENGKFIHIQKKIKDSDKESIITRWLEGDKLITTLESGSVVSRREYVRE
What are the official names of this protein?
Fatty acid-binding protein homolog 6.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein: AROE_AERS4
Sequence: MDRYLVFGHPVRHSKSPFIHTLFARQTQQELEYGLAEPAVDEFATTLRAFFAQGGKGCNVTVPFKEQAFALVDSLSPRAKRAGAVNTIKLTDDGVLLGDNTDGAGLVADLKSHGVALAGSRILLLGAGGAARGALAPLLAEHPTELVIANRTHAKAQQLAAEFHDLGVVTALTYEQLGGTFDLIINSTSASLQGELPPLSPALIHADIAIYDMMYGSMDTPFISWAKQYGARQAMDGLGMLVEQAAEAFTVWRGIRPGTKQVLRELKRNLGTL
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.