PharMolix/UniProtQA huggingface dataset:
Protein: ACADV_HUMAN
Sequence: MQAARMAASLGRQLLRLGGGSSRLTALLGQPRPGPARRPYAGGAAQLALDKSDSHPSDALTRKKPAKAESKSFAVGMFKGQLTTDQVFPYPSVLNEEQTQFLKELVEPVSRFFEEVNDPAKNDALEMVEETTWQGLKELGAFGLQVPSELGGVGLCNTQYARLVEIVGMHDLGVGITLGAHQSIGFKGILLFGTKAQKEKYLPKLASGETVAAFCLTEPSSGSDAASIRTSAVPSPCGKYYTLNGSKLWISNGGLADIFTVFAKTPVTDPATGAVKEKITAFVVERGFGGITHGPPEKKMGIKASNTAEVFFDGVRVPSENVLGEVGSGFKVAMHILNNGRFGMAAALAGTMRGIIAKAVDHATNRTQFGEKIHNFGLIQEKLARMVMLQYVTESMAYMVSANMDQGATDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFMKEPGVERVLRDLRIFRIFEGTNDILRLFVALQGCMDKGKELSGLGSALKNPFGNAGLLLGEAGKQLRRRAGLGSGLSLSGLVHPELSRSGELAVRALEQFATVVEAKLIKHKKGIVNEQFLLQRLADGAIDLYAMVVVLSRASRSLSEGHPTAQHEKMLCDTWCIEAAARIREGMAALQSDPWQQELYRNFKSISKALVERGGVVTSNPLGF
What is the function of this protein?
Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (PubMed:7668252, PubMed:9461620, PubMed:18227065, PubMed:9839948, PubMed:9599005).  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (PubMed:7668252, PubMed:9461620, PubMed:18227065, PubMed:9839948).  Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 12 to 24 carbons long primary chains (PubMed:21237683, PubMed:9839948).
What are the official names of this protein?
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial, VLCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: SYG2_YEAST
Sequence: MPLMSNSERDKLESTLRRRFFYTPSFEIYGGVSGLFDLGPPGCQLQNNLIRLWREHFIMEENMLQVDGPMLTPYDVLKTSGHVDKFTDWMCRNPKTGEYYRADHLIEQTLKKRLLDKDVNPQDMKNMEKILTTIDGFSGPELNLVMQEYNINDPVTNDVLDALTSFNLMFETKIGASGQLKAFLRPETAQGQFLNFNKLLEINQGKIPFASASIGKSFRNEISPRSGLLRVREFLMAEIEHFVDPLNKSHAKFNEVLNEEIPLLSRRLQESGEVQLPVKMTIGEAVNSGMVENETLGYFMARVHQFLLNIGINKDKFRFRQHLKNEMAHYATDCWDGEILTSYGWIECVGCADRAAFDLTVHSKKTGRSLTVKQKLDTPKERTEWVVEVNKKFFGSKFKQKAKLIESVLSKFSQDELIRRHEELEKNGEFTCQVNGQIVKLDSSLVTIKMKTTLQHIREYIPNVIEPSFGLGRIIYCIFDHCFQVRVDSESRGFFSFPLQIAPIKVFVTTISNNDGFPAILKRISQALRKREIYFKIDDSNTSIGKKYARNDELGTPFGITIDFETIKDQTVTLRERNSMRQVRGTITDVISTIDKMLHNPDESDWDKSTFGLSPVKI
What is the function of this protein?
Catalyzes the ATP-dependent ligation of glycine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (Gly-AMP) (PubMed:23816885).  Also produces diadenosine tetraphosphate (Ap4A), a universal pleiotropic signaling molecule needed for cell regulation pathways, by direct condensation of 2 ATPs.  Thereby, may play a special role in Ap4A homeostasis (By similarity).
What are the official names of this protein?
Glycine--tRNA ligase 2, Diadenosine tetraphosphate synthetase, Ap4A synthetase, Glycyl-tRNA synthetase 2, GlyRS 2, GlyRS2.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH4_XANCP
Sequence: MSTTLPDIAVTEPSALHAPLRWVGMQDIAIPVRLDEAEPSGTVAARAQVQVDLPRPELKGIHMSRLYRLLDRHLEQPLSPAMLSQLLQAMIDSHADCGSRAARVSLAFEVMLRMPALRSEGLAGWRAYPVRIDAQSRAGRSEMRLQIDVLYASTCPCSAALSRQLLSKAFAQQHAGQTALRVEDVAQWLQRNGSYATPHSQRSVAQVRVDLVARVQSFDIRALVLLCESALATPVQAAVRRIDEQAFARLNGANLMYVEDAARRLRKELAERYASFHVAVRHFESLHAHDAVAETGSDADVFHMIAESHGQ
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: FLBT2_BRADU
Sequence: MKISLRAGERIYINGAVLRVDRKVSVELVNDVMFLLEGQIMQASDATTAMRQLYFIVQLMLMNPTDVRDASALYGQHHAALVAVCESREMLDGLVAIDELVGATRYFEALKRIRALFPVEQAILAGVATDIPFEAA
What is the function of this protein?
Has a post-transcriptional repressor function in flagellum biogenesis.  Associates with the 5'-UTR of fljK mRNA and promotes its degradation.
What are the official names of this protein?
Probable flagellum biosynthesis repressor protein FlbT 2.
What is the protein family that this protein belongs to?
Belongs to the FlbT family.
Protein: RHAM_SINFN
Sequence: MEKYAFRMRLNPGMAEEYRARHDAIWPELVTLLKEAGISDYSIHLDEETGLLFGVLWRTENHTMADLPSHPVMQKWWAYMADIMETRADNEPVAVPLKTVFHLS
What is the function of this protein?
Involved in the anomeric conversion of L-rhamnose.
What are the official names of this protein?
L-rhamnose mutarotase, Rhamnose 1-epimerase, Type-3 mutarotase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose mutarotase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_HALMA
Sequence: MARMHTRRRGSSDSDKPAADEPPEWSDVDEDAIEARVVELAEQGHSPSEIGLKLRDEGVQGTPIPDVSLATGKKVTEILEENEAEPDLPEDLRNLLERAVRLRDHMDENPGDYQNKRALQNTQSKIRRLIDYYRGDEVDENFTYSYDNAVEALGLE
What are the official names of this protein?
30S ribosomal protein S15, H-S11, HmaS15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: DNLJ_ANAPZ
Sequence: MSDNDSRRRLADLNAQLKLHDVLYHEHDAPEISDAQYDALVQEKRELLEKFPELSAYNDYEGVIGALTVDARLPKIAHREPMLSLENSFTIQDVEKFISRVKRSLNMDPEVSITIACEPKIDGLSFAALYEKGSLIRVATRGNGHLGEDITNTAKVIRKLPHKIANAPEVLEVRGEIYMHHSDFEKLKDVCNFANPRNAAAGSIRQLNPKIAEERNLRYVAYCIVNSALASQEAILKQLAEWGFCTHTEVLFADNMDDALSFHTRMYNTRSTLGYDIDGIVYKVNDTHLQKLLGSTSKYPRWATAHKFPSTEAITKLRDISVQVGRTGVITPIAELEPINIGGTLVSRASLHNLNEIARKDIRIGDSVIVKRAGEVIPQVVGVDHTARCNSAVPEEYVFPSHCPSCGSTLSRAPGEVAMRCTAELSCQAQVLERVKHFVSRDGLNIVGLGEKQIEFFCNASYISNVADIFSLREKISHMNLSAEHGWGEKSIALLINAINASTTVKLSNFIFALGIRFIGKGAAKLIAEHYRSYSAWVRAMTSLANGEDPDNIHGIGLKSIESLRAFFSSEDNLRVLQTLEEKLNILNEIANTETASPISGKTIVFTGVLEDMSRNEAAKYAETLGAKVGNTVTTKTDILVAGSNSGSKLDTARKLGIQVMNESEWKDLLKTVSNSE
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: ZFP28_MOUSE
Sequence: MQGMASVVSCEPWALLGRGALCTKARPGGGPAAGTVVAPGSPDRGRPRSRNSLASQDQQGAVTSGTAHKALFSRDTNFLQEINRKQEAAPTGTRHKAKSQGLVTFGDVAVVFSQEEWEWLNSEQRSLYWKVMLDNYRNLASLGLCASQPDMITSLEQGRDPWMMKRKMRKGQHLDLKAMQETKEFPPKDLSEETLFLAVLRKQLLPHRPKCSMVRAAWEGGAVFTTHRGLKTNSGLARDSPAQLVSAQRSFCKSVTWENCGDRGSVGQQSVQEAQDLLPRQDSHAERVTGRTWSTKLECSTFRDQDSECTFERNEQETVTPNRAFSEGRDGMCIESGRWFHLNSSDERSHNCDSGKSFSSNPVVVKETGICSGKKLFQCNECKKTFTQSSSLTVHQRIHTGEKPYKCNQCGKAFSDGSSFARHQRCHTGKKPYECPECGKAFIQNTSLVRHWRYYHTGEKPFDCIDCGKAFSDHIGLNQHRRIHTGEKPYTCEVCHKSFRYGSSLTVHQRIHTGEKPYECEICRKAFSHHASLTQHQRVHSGEKPFKCKECGKAFRQNIHLASHWRIHTGEKPFECGECGKSFSISSQLATHQRIHTGEKPYECKVCRKAFTQKAHLAQHQKTHTGEKPYECKECGKAFSQTTHLIQHQRVHTGEKPYKCLECGKAFGDNSSCTQHRRLHTGQRPYECVECGKTFKTKSSLICHRRCHTGEKPYECSACGKAFSHRQSLSVHQRIHSGKKPYECKECRKTFIQIGHLNQHKRVHTGERTYNYKKGRRAFRQTAHFAHHQQIHSGKSPAHHSLPSTSNPVDLFSKFVWNPSSLPSS
What is the function of this protein?
May be involved in transcriptional regulation.  May have a role in embryonic development.
What are the official names of this protein?
Zinc finger protein 28, Zfp-28, Protein mKR5.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: QUEF_PARMW
Sequence: MTDQLTQTPLYGERAIAEAELICFDNPRPGRPYEVSIELPEFTCKCPFSSYPDFAVLRLIYQPGPRVVELKAIKLYVNSYRDQSISHEEVTNRILDDLVAATDPVWMQLEADFNPRGNVHTVVRVSHGTRQPC
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAB_HALHL
Sequence: MSRNQSREARPNREVAQTVSERVYVETQGCQMNDYDAERLVDVLVSQAGARRVDRPEEADLLLLNTCSVREKAQEKVFSQLGRWRRYKQDNPTVLIGVGGCVASQEGAEILRRAPFVDLVFGPQTLHRLPQMLARRRSGASAQVDVDFPEIEKFDHLPQPRAEGPTAYVSVMEGCSKYCSFCVVPYTRGDEISRPVADVLAEVRSLAEQGVREVNLLGQNVNAYAGALDDGERADLGLLIEAVARIPGIDRIRFTTSHPAEFHSGLIDAYRDVPELADFLHLPVQSGSDLILKLMKRGHDIAAYEALIDQIRAVRPGLVLATDLIVGFPGETEAEFEETLAMVDRVGFDGGAFSFVYSPRPGTPAAELHDGVPEADKRAWLQRLQARLHEQQSAAARALLGTRQSVLIDGPSRRDPRELSGRTSGNRVVNFPGDPSWIGRFAEVEITDARTHSLRGRVVSVEGQAMHAAVGAGG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCNB3_MOUSE
Sequence: MPPPLLPKRSKLETEKAQSNKITPREEQQSEKIGKSNHAASSSSSSTQGAVKRRSVFEDVTNASHSQCVQSKEDNIELKSHVSKRTKKGVGEVTQKKIKSSKMGHVTSLSNMEKEFILDIPNKPKTLTTEEPSVFQKTLVLNEEPATKETCLMRKTLKSCAFHQETLLMEKPLTLLVETEDYNEFDTELMTSKKKDKPEDPTIIEEMTDLKKSVIRKVTLTSSPLWLKNKHVVQEEKPVIQEKSSFKRISLVSNVVTTKEKPPVKKPHFRKKKPTTEMKSLLQEPSLEEKYNTQEDASILKKPQVLQENTNNKDATLTEPVTFKGKHSANEATHTKKPSSSKNNPDPQGKGTNLRPLRVHPVTYENEPMSSKKSTTKKKDSHFHGPSVLPDKHSPQMEVSTVKKSLALPNPTTEEKMLHFPVATVLEKQHNMGEAPCLKKPSPLRKQQQLPKRRRFFSNSAVQETVIRKPLFFKMSTTEKDPPSQWPSALPKKHISPGELSKQKKQHVSPKHNMEEDSQCWLDSAFKKQLSREEPASTHTPLKLEMQQAITKETGFHLRNPLVLPTVTSEAKSLTKEPPSFREQNTSLLKRKSTTHTITLQQAQSEWQEMTDEDRNLFSIKPGSHRKEPIPEFLQNPLPPNENCLISQKLSHSMPFASQKTTSQERAHRKESVASNDDKNFFSQDLFSPFSSADEDTLKFHKSLDFQEQVDRKNDSHKKMFDSQDSVSEEESFLRKLFCKDRCSSTEELSQERTVALEQEFLLIKILNENTSSDVDEPLSHQSPHIQNHSDTTKEALEASEALEAPEALETLEALVASEDLEEPLNILEELSTENMVALMKMLVTEDESTKDSFSGNYTAAREAHAEKSLSLEETSINEAATLKESLSSQEKHRAELVTVLKELLVLMKNPSLKRVALAFQENPSNNVETLLREVLALVENSTADESTLQEKPSTKTDVTPKELLALEENSSNKKANPMDSLSFDHKPDTEMGEIARMVLTDEEYNIDTLYERVLALSQGLIAADQLSFTDLQNFEETKIVDEEEFFKSFLVFENKNSPNMSSNAFESRTDNSSAIMPSSKAFNPVENSNPYVSSSKSFKSTLGAKETEITIQDDSDSLERIEKEGQDPLLNTIYAKDVFNYLKEREEKFLVQKYMDGQMELTSDMRAILVDWLVEIQGSFQMTHETLYLAVKIMDLYLMKAQCKKNHLQLLGSTTYMIAAKFEESYPPSLSEFLFICEDMYEKSDMVSLESSILQTLNFDINIPTAYNFLRRYASCIHASMKTLTLSRFICEMTLQEYEYIEERPSKLAAASFILALYMRNLSNCVPTLEYFTGYKMAELHILVRKLNHLLNFRSHSILKNVFEKYSEETYFEVAKIPPLSKQDLENLLNCALFH
What is the function of this protein?
Cyclins are positive regulatory subunits of the cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division.  Its tissue specificity suggest that it may be required during early meiotic prophase I (By similarity).
What are the official names of this protein?
G2/mitotic-specific cyclin-B3.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin AB subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: OBG_NEIMF
Sequence: MKFIDEAKIEVAAGKGGNGATSFRREKFVPRGGPDGGDGGKGGSVWAEADENTNTLVEYRFVKRYQAKNGEKGHGSDRYGAGADDIVLKMPVGTLIRDLDTDEIVADLTYHGQRVCLAKGGKGGLGNIHFKSSVNRAPKQSTPGEEGEARSLQLELKVLADVGLLGMPNAGKSTLITAVSAARPKIANYPFTTLHPNLGVVRIDENHSFVMADIPGLIEGAAEGAGLGHRFLKHLSRTGLLLHVVDLAPFDETVNPAEEALAIINELRKYDEELYGKPRWLVLNKLDMLDEEEAQTRTAAFLEAVGWDYPKPDDRFQFDMETPRLFQISALTHQGTQELVHQINQYLTEKKRIEAEKAEAEKAAANVEIIEQQPKTDTGVFKPE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_KLEP3
Sequence: MRSSAKQEELVKAFKALLKEEKFSSQGEIVQALQEEGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGSIAGDDTIFTTPARGFTVKDLHDAILVLFEQEL
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS15_SACEN
Sequence: MALSTAEKKQILAEYGLHDSDTGSAEAQVALLTKRIIGLTEHLKQHKHDHHSRRGLLLMVGRRRRLLNYLTKVDIERYRSLIQRLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: HIS6_BACAA
Sequence: MLAKRIIPCLDVKEGRVVKGVNFIGLQDVGDPVEIAALYNDAGADEIVFLDITATHEGRKTIIDVVEKTASKVFIPLTVGGGISSVKDMYNLLRAGADKVSINSAAVRNPKLIEEGAQHFGSQCIVVAIDARKVAEGKWNVYVNGGRVDTGMDAIGWAKRVVMLGAGEILLTSMDADGTKNGYDLRLTEEISKSVSIPVIASGGCGHADHIIEVFQKTTVDAALAASIFHYGEATIGDVKRKLRNANVEVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REV_HV1MN
Sequence: MAGRSGDSDEELLKTVRLIKFLYQSNPPPSSEGTRQARRNRRRRWRERQRHIRSISAWILSNYLGRPAEPVPLQLPPQRLTLDCSEDCGTSGTQGVGSPQILVESPTVLESGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What is the protein family that this protein belongs to?
Belongs to the HIV-1 REV protein family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: RECR_LACDA
Sequence: MQYPLPIARLIDSFMKLPGIGEKTATRLAFYAMDMPKEDVDEFAQALVDVKEKLRQCSVCGNITEQDPCAICSNPVRDRSTIMVVEEAKDVMAFENMGEYDGLYHVLHGVLSPMDGIGPEQINIKSLIVRLQKNDAAKEVILALNSTPEGESTAMYISRLIKPAGLKVTRLAAGLAVGSDIEYANLITLKRAVQGRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RF3_HAEI8
Sequence: MSYPLEEVNKRRTFAIISHPDAGKTTITEKVLLYGNAIQTAGSVKGKGSAAHAKSDWMEMEKQRGISITTSVMQFPYNNCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDSAKGVEERTIKLMEVTRLRDTPIITFMNKLDRDIRDPMELLDEVENVLKIRCAPITWPIGCGKLFKGVYHLAKDETYLYQSGQGSTIQAVRVVKGLNNPELDVAVGDDLAQQLRDELELVQGASNEFEQDAFIKGELTPVFFGTALGNFGVDHFLDGLTQWAPKPQSRQADTRTVESAEEKFSGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLKHVRIGKDVVISDALTFMAGDRAHAEEAYAGDIIGLHNHGTIQIGDTFTQGETLKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPLLNNDLIVGAVGVLQFDVVVSRLKTEYNVEAIYENVNVATARWVECADGKKFEEFKRKNEQNLALDGGDNLTYIAPTMVNLNLAQERYPDVVFYKTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROE_ECO5E
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFVNTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKPTADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: LYS2_CANAX
Sequence: MTDFWLNYLDNPTLSVLPHDFLKPANNKSVEGTYTFNIDNGSTDFKFGLAVFAALVYRLTGDEDIVIATDESANTPEFIVRLNLTPELTFQELVSKITKEYENNISQINYKALSEVSHRIKEAKGLDENPGLFRLSYQHAHSNQQLNTTVEGSIRDLAIYTDGTKFTIYYNALLYSHERVVICGEQFAQLTTVSGDTDTVIAEVFLITDFHKKNLPDPTIDLDWSGYRGAIQEIFMDNANKHPDRTCVVETVSFLESNSKTRNFSYHKLIKLLIVVGNYLKETGIKKGDIVMIYAYRGVDLMIAVMGVLKAGATFSVIDPAYPPARQNIYLSVAKPKGLIGLEKAGTLDQLVVDYISNELDVVSTIPQLKVQDDGTLVGGKLEGADNDCLNDYQKFKDQPAGVIVGPDSRPTLSFTSGSEGIPKGVLGRHYSLAYYFPWMAKRFRLSEKDKFTILSGIAHDPIQRDMFTPLFLGAQLLVPTADDIGTPGKLADWMAKYGATVTHLTLAMGQLLSAQATTAIPSLHAFFVGDILTKRDCLRLQSLAENVFIVNMLWSLSQTQRSVSYFEIKSRKADPTYLKNLKAVMPAGTGMHNVQLLVVNRNDRSQTCGVGEVGEIYVRAAGLAEGYRGLPDLNAAKFITNWYVNPDKWIEQDEANKKSSETSERTWSVKPRDRMYRSGDLGRYFSDGNVECCGRADDQVKIRGFRIELGEIDTHLSQHPLVRENVTLVRRDKNEEPTLISYIVPKDSPELKTFFADVDFPLKKSNDPIVKGLVAYRELIKDIKGYLKKKLASYAIPTIIVPLVKLPLNPNGKVDKPKLPFPDTAQLAAVAKLSVSSHDAQAAEEENLTKLEEQIRDLWLDVLPNRPATISKDDSFFDLGSHSILGTRIFTYEQKLNVEIPLVSFKGDQRRPRFPIGLSRYNYSRREQRCRRFLKAKTYTMRRSKELSKELSKSALLESYSSLKQLPSGSVNVFVTGATGFLGSFIVRDLLTARNKNLDIKVYAHVRASSKEAGLQRLRQTGITYGIWDENWAEKIEIVLGDLSKEKFGLDNSQWSDLTNSIDVLFTMVLCHWVYPYSQLRMLNVIGTINVFNMAGEVKLKFFSFVSSTSALDTDYFVNLSDELLAQGKNGISEADDLQGSAKGLGNGYGQSKWAAEYIIRRAGERGLKGCITRPGYVAGFSKTGASNTDDFLLRMLKGSAELGLYPDITNNVNMVPVDHVARVVTATALNPPSSEELTVAHVTGHPRILFNNFLGCLKAYGYEINPADYPVWTSALEKFVIEESKESALFPLLHFVLDNLPQDTKAPELDDSNAAKSLKQDSKYTGEDFSAGKGVDLDQTGVYISYLIKIGFLPKPTGTGEKKLPEVEISDESLKLISGGAGARGSAAK
What is the function of this protein?
Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH.  The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.
What are the official names of this protein?
L-2-aminoadipate reductase large subunit, Alpha-aminoadipate reductase, Alpha-AR, L-aminoadipate-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: PANB_ANAD2
Sequence: MSSHPPAPRKHVTIHELRRMKESGERIAMVTAYDATAARLVAVAGVDAVLVGDSLGMAVQGHESTLPVTLDQMVYHSAMVRRGLARGDGRAHLVTDMSFGSYQASADEAVKAAMRLVAEGGAEAVKLEGGAEFGEVIRRIVRAGVPVMGHIGLTPQSVHKMGGYVVQGKDSEKAQQILRDARALEAAGCYALVLECIPSELARIVTSQLRIPTIGIGAGPHCDGQVLVLNDLLGLDASFTPRFVKRFGEVGAAVQDAVGAYVGEVKARAFPDDAHSFHSSSVRLVPVERHAEAAEEEPPDAIGAPI
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_SALPA
Sequence: MSVSAFNRRWAAVILEALTRHGVRHVCIAPGSRSTPLTLAAAENPAFIHHTHFDERGLGHLALGLAKVSQQPVAVIVTSGTAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQAGMFASHPSQTLSLPRPTQDIPARWLVSTIDNALAMLHAGALHINCPFAEPLYGDMNDTGLVWQQRLGDWWQDEKPWLREARRLASDKQRDWFFWRQKRGVVVAGRMSAEEGKKVAQWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKAVTELQQAQIVVQLGSSLTGKRLLQWQATCEPEEYWVIDNIEGRLDPAHHRGRRLVAKIADWLELHPAEKRKPWCVGIPRLAELAWQRVVAQRDTFGEAQLAHRIRDYLPEQGQLFVGNSLVVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASAKSTLAIVGDLSALYDLNALALLRQVSAPFVLIVVNNNGGQIFSLLPTPQSKRERFYLMPQNVHFDHAAAMFNLRYHRPENWEELESALAGAWRTPATTVIELVVNDTDGAQTLQQLLAQVSHL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: SYSM_ARATH
Sequence: MGLHKLRLAAAVPVTFSSRLFLKPFTNTLTLGLFSRHLQPRNKPLLVRAFSASAAVQDIPATQTSDSSVAARPLWKAAIDFKWIRDNKEAVEINIRNRNSNANLEAVLQLYENMVNLQKEVERLREERNNVAKKMKGKLEPSERERLVEEGKNLKESLVTLEEDLVKLKDELQHVAQSIPNMTHPDVPVGGEDSSAIRQEVGSPREFSFPIKDHLQLGKDLDLIDFDSAAEVSGSKFFYLKNEAVLLEMALLNWTLSQVMKKGYTPLTTPEIVRSSIVEKCGFQPRGDNTQVYSIDGTDQCLIGTAEIPVGGIHMDSILLESALPLKYIAFSHCFRTEAGAAGAATKGLYRVHQFSKAEMFVICQPEDSESFHQELIQIEEDLFTSLGLHFKTLDMATADLGAPAYRKFDIEAWMPGLGRFGEISSASNCTDYQSRRLGIRYRPSEPPQTGPKKGKANLPATKFVHTLNATACAVPRMMVCLLENYQQEDGSVVIPEPLRPFMGGIELIKPKHK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).
What are the official names of this protein?
Serine--tRNA ligase, chloroplastic/mitochondrial, AtSRS, Protein OVULE ABORTION 7, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Mitochondrion.