PharMolix/UniProtQA huggingface dataset:
Protein: RSMJ_ECOLI
Sequence: MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DF268_ARATH
Sequence: MARLIFHFVFALILAAYLLSVTDAIPRGWQEPCFCPSKNPYCDCGDDLQVPTTSVISPKPIIEQCARCERNSQCNKVCPATCKYKVCIFNRTCEFSTCHCYRC
What are the official names of this protein?
Defensin-like protein 268.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOLD_CYTH3
Sequence: MQLLDGKITSDQIKEELKTKVEAIKAKGGKIPHLAAVLVGDSGAAVTYVNAKVKACELVGFKSTLVKLPETITEADLLAKVAEINADKDIDGYIVQLPLPKHIDEQKVTEAISPDKDVDGFHPTSLGRMVLNLPTYLPATPYGIMQLLERNGIETSGKHCVVMGRSHIVGSPMSILMARNTNPGNATVTMVHSRTKNLKELTLQADILIVAIGKPEFVTADMVKEGAVVVDVGIHRIDDATKKSGFRLLGDVKFDEVAPKTSYISPVPGGVGPMTIASLLMNTLQAAALK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: LDH3_BACAN
Sequence: MKRHTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYQVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGGKPILQILEEQKERFGEIDLDEIVEKTAKAGWEIYKRKGTTYYGIGNSLAYIASSIFNDDHRVIAVSAILDGEYGEYDICTGVPAIITRDGIREIVELNLTEDEESRFAKSNDILRDYMKTIGY
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 3, L-LDH 3.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYRA_CLOAB
Sequence: MLNEGKVLPVDISSEMKKCYIDYAMSVIVSRALPDVRDGLKPVHRRILYSMHELGLTPEKGYRKCARIVGDVLGKYHPHGDSSVYGALVRLAQDFNLRYTVVDGHGNFGSVDGDSAAAMRYTEAKMNKIALEMVRDIGKNTVDFIPNFDGEEKEPVVLPSRFPNLLVNGSAGIAVGMATNIPPHNLGEVIDGITMLIDNPEATILELMAQIKGPDFPTAGIIMGKSGIRAAYETGRGKITVRAKSEIEVEDNGKQKIIITEIPYQVNKARLVESIADLVKDKRIVGISDLRDESDRDGMRIVIEIKKDANSNIILNQLYKHTRLQDTFGINMLALVDNRPEVLNLKQILQHYIKFQEQVIRRRTEFDLEKASARAHILEGLKIALDHIDEVISLIRGSKTAQEAKLGLMDKFGLSEKQAQAILDLKLQRLTGLEREKIEDEYNELMKTIAELKSILADENKILAIIRDELNEIKAKYGDERKTAIERAENDIDIEDLIQEENVVITLTHAGYIKRINADTYTSQKRGGRGIQAMTTKEDDFVENIFITSTHNNILFFTNKGRMYKLKAYQIPEAGRAAKGTNVVNLLQLDPNEKIQAVISIKEFDEESFLVMCTKKGIIKKTVVGMYKNIRKSGLIAINLNDDDELVSVRITKGDDDIIIVTNKGLAIRFNEVDVRPLGRNALGVKGITLKEDDFVVGMEVPNQESDVLVVSENGFGKRTHVGEYKCQHRGGKGLITYKVSDKTGKLVGVRMVEDGDELMLINNLGIAIRINVSDISTTSRNAMGVTLMRNNGDEKVLALAKINKDDSEQLEDSEEVSEVHDAEENNSEE
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit A.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrA/ParC subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_MARMS
Sequence: MDYSVNKMQLPSPAKLNLFLHITGRREDGYHELQTLFQFIDLCDTLDFSLTRNNQITISPIIEQLPTEDNLIYKAAKLLTPFKKDSTFGIDIILTKQLPMGGGIGGGSSNAATALLALNVLWGCQLSLEKLAELGVQLGADIPVFVMGFAAFAEGVGEKLQKVELDTPYFLLIKPNCHVSTGQIFTDKYLTRDTPPIRISHALKLGGHNDCLDVVKKHNPEVNEAYLWLKNYGDAKLTGTGACLFLAFDNLRDAERVRSSTPTKWQSWVCRGCNTSPTHAALNQWIEQNRGVPHIKHHLSQSFLG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: FOXJ2_XENTR
Sequence: MASDLGSSLTSIDWLPQLTIQAAMKGSQQNNAGRKGPGSPTDPSAMLSKEEAAAHRDGKPPYSYANLIQYAINSAPAKRMTLSEIYRWICDNFPYYRNAGVGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWMIDSCPKEDVALPRRKRPHPDDEVSQDSFEQDVNKSPLRSASEVSMPQEGTQGHPMNNNSPLPSYSQANPTQMPPDSRAPTYNNNDCYKFSFSESTFPDLGCSFRSLYHSLLGKQGERGDKDLYNSMQSKQVLPPVHSEVQSSSCCMYQQNSGAAPSNLHPHNVPSISGPPPPHHQAQHQQPPYLPQQQMPRPPAPGMSLGLPSDWCSNIDSLKESFKIVSSLDWSSVDLSQFSDLMESLRQAELKNWSLDQDHIASLCDSLSHLLSTTGLLPPTHGQPPSCQAPCMPPTTSSACALRGGKPVHNMTVNSYGQNQPPPVSCGHTFTASSGYPIQSQAPPTYSQQGRHPQRALYPPQRPTLRYPQSSDDIQDDFDWDSIA
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Forkhead box protein J2, XtFoxJ2, FoxJ2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DER_RHIL3
Sequence: MSFTVAIVGRPNVGKSTLFNRLVGKKLALVDDTPGVTRDRRPGDARLMGLTFTIIDTAGLEEADAESLQGRMRAQTEAAIDEADLSLFVVDAKSGLTPVDTDLAEMLRRRGKPVVLVANKSEARGSDSGFYDAYTLGLGEPTPISAEHGQGMLDLRDAIVAAIGEDRAYPEKEDVAVTDVDIPQSSDEGDEDEEPIYDDTKPLRVAIVGRPNAGKSTLINRFLGEDRLLTGPEAGITRDSISVEWDWRGRTIKMFDTAGMRRKARVIEKLEKLSVADALRAIRFAETVVIVFDATIPFEKQDLQIVDLVLREGRAAVLAFNKWDMIEDRQAVLADLREKTDRLLPQARGIRAVPISGQTGWGLDKLMQAIIDTDKVWNKRISTARLNRWLETQQVQHPPPAVSGRRIKLKYMTQVKARPPAFMISCTRSDALPESYTRYLINGLRADFDMPSVPIRIHFRSPDNPFEGKKRRT
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ZDHC6_BOVIN
Sequence: MGTFCSVVKFENLQELKRLCHWGPIIALGVIAICSAMAMIDSVLWYWPLHTTGGSVNFIMLINWTVMILYNYFNAMFVGPGFVPLGWKPENSQDSVYLQYCKVCQAYKAPRSHHCRKCNRCVMKMDHHCPWINNCCGYQNHASFTLFLLLAPLGCIHAAFIFVMTMYTQLYNRLSFGWNTVKIDMSAARRDPLPIIPFGLAAFAATLFALGLALGTTIAVGMLFFIQMKIILRNKTSIESWIEEKAKDRIQYYQLDEVFVFPYDMGSRWKNFKQVFTWSGVPEGDGLDWPIREGCHQYSLTIEQLKQKADKRVRSVRYKVIEDYSGTCCPLNRGIKTFFTSPCTEEPRIRLQKGEFILATRGLRYWLYGDKILDDSVLEGVSRIRGWFPRNCVEKCPCDAETDQAPEGEKKNR
What is the function of this protein?
Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC (By similarity).  Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (By similarity).  Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum (By similarity).  Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function (By similarity).  Stearoyltransferase that mediates stearoylation of TFRC to inhibit TFRC-mediated activation of the JNK pathway and mitochondrial fragmentation (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC6, Stearoyltransferase ZDHHC6, Zinc finger DHHC domain-containing protein 6, DHHC-6.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=When not palmitoylated, accumulates to dot-like structures in the endoplasmic reticulum.
Protein: GRPE_RICPU
Sequence: MIDDNIENNEQTINDIAEEIVETANPEVTALKAEIEELKDKLIRTTAEIDNTRKRLEKARDEAKDYAIATFAKELLNVSDNLSRALAHKPANSDVEVTNIIAGVQMTKDELDKVFHKHHIEEIKPEIGSMFDYNLHNAIAQIEHPDHAPNSIITLMQSGYKIRDRLLRPATVQVVKKP
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMB_PSYIN
Sequence: MTDQEHSASEENADSVEKHKYMRKIRSFVKREGRMTNRQQTAIDTLWDTMGIDFEEKLIDFNALFGRQAPIVLEIGFGMGKSLIEMAKNAPEKNFIGIEVHGPGVGACLADAGEAGVTNLRVINHDAVEVLDKMIPDNSLAVFQLYFPDPWHKARHHKRRIVQPHFIENMRHKLAIGGVIHMATDWENYAEHMLAVLQASPDFKNTSESDYAPRPEWRPLTKFENRGNNLGHGVWDLLFERIS
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: RAS1_MAGO7
Sequence: MTGRLQLHKLVVLGDGGVGKTALTIQLCLQHFVETYDPTIEDSYRKQVVIDNQACMLEVLDTAGQEEYTALRDQWIRDGEGFVLVYSISSRSSFSRIKRFHHQIQRVKESCASSPSYPGSPIATVTTQAPVPIMLVGNKSDRVTEREVSTQEGHALARELGCEFVEASAKNCINVEKAFYDVVRILRRQRQQASRPSLPGNSRTKTGGMGKSESFYQSDGKRGSRKDGEKHRSKPIKCVIL
What is the function of this protein?
Modulates the activity of the adenylate cyclase catalytic subunit and therefore affects the biosynthesis of cyclic-AMP (By similarity).  Plays a role in both surface attachment and surface recognition of appressoria, a highly specialized infection structure for plant penetration.  Regulates appressorium formation by coordinated regulation of cAMP signaling and Pmk1 MAPK pathways (By similarity).
What are the official names of this protein?
Ras-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: GSIC_SHIF8
Sequence: MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEADAQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLTITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMFLIQVFSVELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEILLFSLEFILINLVVDVLYAAINPAIRYK
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RDH14_HUMAN
Sequence: MAVATAAAVLAALGGALWLAARRFVGPRVQRLRRGGDPGLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGAQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGLLK
What is the function of this protein?
Retinol dehydrogenase with a clear preference for NADP.  Displays high activity towards 9-cis, 11-cis and all-trans-retinol.  Shows a very weak activity towards 13-cis-retinol.  Has no activity towards steroid.
What are the official names of this protein?
Retinol dehydrogenase 14, Alcohol dehydrogenase PAN2, Short chain dehydrogenase/reductase family 7C member 4.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RS3_PROMA
Sequence: MGHKIHPNGLRLGITQEHRSRWYASSKTYPLLLQEDDRIRVFIQKKYGAAGISDVLIARKADQLEVELKTARPGVIVGRQGSGIEELRSGIQKTIGDRSRQVRINVVEIERVDADAHLLAEYIAQQLEKRVAFRRTIRMAVQRAQRAGVLGLKIQVGGRLNGAEIARSEWTREGRVPLHTLRAEIDYANKTANTTYGVLGIKVWVFKGEVLSKEEQPLPVGASPRRKGNRRPQQFEDRSNDGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: THYX_CLOTE
Sequence: MRGKTMGVKVKLLEYTPNPEKVVASAAKLCYSPVGVEEMAKDLSEEKVNKFLNMLMSYGHESPIEHVSFTFAAEGVSRSLTHQLVRHRIASYSQQSQRYVKLDQFQYIIPPEIDKDNNTRSIFIEAMENSQKAYDKIASTLEQKYISEGMKRKEAEKKAIEDARYVFPNACETKIIFTMNARTLMNFFRHRCCTRAQWEIRNLANEMLSEVKKVAPNLFKYSGPSCVNGNCPEGAMSCGKAAEMKKIYL
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
What are the official names of this protein?
Flavin-dependent thymidylate synthase, FDTS, FAD-dependent thymidylate synthase, Thymidylate synthase ThyX, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase ThyX family.
Protein: FLHA_YEREN
Sequence: MANLAALLRLPGNFKDTQWQILAGPILILMILSMMVLPLPPFILDLLFTFNIALSIMVLLVAMFTQRTLDFAAFPTILLFSTLLRLSLNVASTRIILMDGHTGAAAAGRVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEDEAKKRRSDVTQEADFYGSMDGASKFVRGDAVAGLLIMVINVVGGLLVGVLQHNMAVGHAAETYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGQQMVTQLFNNPRVMVLSAAVLGLLGMVPGMPNFVFLLFTAALLALAWRLRGKQSQQPTAAEAPVIQDQQQATEATWSDVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRSIRKKFAQEMGYLPPVVHIRDNLELPPASYRILMKGVEIGSGEAHPGRWLAINPGNAVGTLPGEATQDPAFGLAAVWIESALREQAQIQGFTVVEASTVVATHLNHLISQYASDLFGRQETQQLLDRVSQEMPKLTEDFIPGVVTLTTLHKVLQNLLMERVSIRDMRTIIETLAEHAPNQTDPYELTAVVRVALGRSIAQQWFPGTGEIQVIGLDAALERLLLQALQGGSGLEPGLADRLLEQSRQALQRQEMLGAPPVLLVNHALRALLARFLRRSLPQMVVLSNLEIGDNRQIRMTSTIGVA
What is the function of this protein?
Required for formation of the rod structure of the flagellar apparatus.  Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).
What are the official names of this protein?
Flagellar biosynthesis protein FlhA.
What is the protein family that this protein belongs to?
Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GUAAB_THEVO
Sequence: MSFSDYISRIKDNIRNSIKGKAIIAVSGGQDSSLLSLLASEVLGNNLLCVFIDTGLLRKNETGRVKDFFEKHSMNYVIVDAADTFINNLKGVTDPEEKRKIIGKTFIDVLSEQAQNFGAEYLLQGTIAPDWIESGGQKRDTIKSHHNVGGLPKDMKLKLVEPLRDYYKDEIRGMSKELGLPTDIQPFPGPGLAVRIIGEVTKEKLDLLRAVTDIVERKISEAMPSESRPWQYFAVLLPVRTTGVHGDRRAYGLTVGIRMIETTDAMTGTFSKPSWDLLEDISNTITDEIPEINRVVYDITNKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: ATPE_AGRVS
Sequence: MADNFNFEFVSPERLLISEKVSEVVIPATEGEMTVMAHHAPTMTVIKPGVVTVKFASGKTGKYVIFGGFADITPERLTLLAESAVPVDELSRDTLMKRIELAKAELDDTENHEHRTKLEQFLNAMTHLNGVLVPA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSBD_TOBAC
Sequence: MTIALGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: PYRB_VIBC3
Sequence: MANSLYQKHIISIAELSRAELELIVKTAGQLKAQPNPELIKHKVVASCFFEPSTRTRLSFETAIQRIGGSVIGFDNGGNTSLAKKGETLADSVRVISSYVDAFVMRHPQEGAARLASEFSNGIPVINAGDGSNQHPSQTLLDLYSIFETQGRLDNLDVAFVGDLKYGRTVHSLAQALAKFDNNRFYFVAPEALAMPDYICEELDEAGVKYQVFSDMESVIPELDILYMTRVQKERFDESEYAHIKSAYILTAAHLSDARSNLKVLHPLPRVDEITTDVDKTPHAYYFEQVENGVYAREALLALVLNESL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: VP602_ARATH
Sequence: MKRIFGAKNNKEPPPSIQDASDRINKRGDSVEEKVKRLDAELCKYKDQIKRTRPGPALEAIKARAMRVLKQKKMYEGQRDMLYNQTFNLDQVSFAAEGLKDAQQTMTALKSANKELKGMMKTVKIQDIDNLQDDMMDLMDESSEIQETLGRSYNVPDDIDEDDLLGELDALEADMGNETEADGVPSYLQPDKEPDLNDELNLPSAPMGHTGAPPGRAQAEDEWGLPAVPRASLRG
What is the function of this protein?
Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 60.2.
What is the protein family that this protein belongs to?
Belongs to the SNF7 family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Peripheral membrane protein.
Protein: MSHA_STRGG
Sequence: MPRSRRTDEVSQYVSRLGSTRTAARLRFPGGFSGASRKPRRVAMLSVHTSPLHQPGTGDAGGMNVYIVELAKRLAAINIEVEIFTRATTGSLAPTVELAPGVLVRHVDAGPYEGLAKEELPAQLCAFTHGVMQAWAGQRPGYYDLVHSHYWLSGQVGWLAAQRWGVPLVHAMHTMAKVKNAALAEGDTPEPAARVIGETQIVNASDRLIANTAEEADELVRFYDADPAAVAVVHPGVNLDRFRPFPQGSDELRPGNAPSGRAAARARLGLPQDALIPLFAGRIQPLKAPDVLLRAVAVLLDRDPSLRSRIVVPVVGGPSGSGLAKPEGLQKLAARLGIADVVRFHPPVGQERLADWFRAASVLVMPSYSESFGLVAIEAQATGTPVVAAAVGGLPVAVRDGVGGFLVQGHEPEAYARALGRFADAPELVERMGAAAAAHAQSFGWDTAASATADVYTAALSDHRRRARAHHG
What is the function of this protein?
Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.
What are the official names of this protein?
D-inositol 3-phosphate glycosyltransferase, N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase, GlcNAc-Ins-P N-acetylglucosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. MshA subfamily.
Protein: NIFE_RIPO1
Sequence: MKLTKGKINELLTQPGCEHNHNKEGQGKNKSCTQQAQPGSAQGGCAFDGASIALVPITDAAHLVHGSIACSGNSWNSRGSLSSGPMTYKMGFTTDLSENDVIFGGEKKLYQAIAQLVKRYHPAAVFVYSTCVTALIGDDLDAVCKAATKKYETPIIPVHAPGFVGSKNLGNRLGGEALLDHVVGTREPEFTTDFDINLIGEYNVAGEMWGVLPLFEKLGIRVLAKITGDARYEEVCYAHRAKLNLMICSKALINMATAMQERYGIPYIEESFYGIADMNRCLRNIAEYFGDAALKERVEQLIEEETTKLDLALAPYRERLKGKRVVLYTGGVKSWSVVSAAQDLGMEVVATSTKKSTEEDKAKIRELLGKDGIMLEKGSPTELLRVVEQTKADLLVAGGRNQYTALKARIPFLDINQERHHPYAGYVGMIEMARELDEAVHSPIWRLVRQPSPWDIWQQEHESLLNLEAE
What is the function of this protein?
This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor).
What are the official names of this protein?
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE.
What is the protein family that this protein belongs to?
Belongs to the NifD/NifK/NifE/NifN family.
Protein: EST1F_RAT
Sequence: MCLSFLFLVSLATCVVYGNPSSPPVVDTTKGKVLGKYVSLEGVTQSVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTTYPPMCSQDAAKGQRMNDLLTNRKEKIHLEFSEDCLYLNIYTPADFTKNSRLPVMVWIHGGGMTLGGASTYDGRVLSAYENVVVVAIQYRLGIWGFFSTGDEHSRGNWGHLDQVAALHWVQDNIANFGGDPGSVTIFGESAGGFSVSVLVLSPLTKNLFHRAISESGVVFLPGLLTKDVRPAAKQIADMAGCETTTSAIIVHCLRQKTEEELLEIMKKMNLIKLSSQRDNKESYHFLSTVVDNVVLPKDPKEILAEKNFNTVPYIVGINKQECGWLLPTMMGFVPADVELDKKMAITLLEKFASLYGIPEDIIPVAIEKYRKGSDDSIKIRDGILAFIGDVSFSIPSVMVSRDHRDAGAPTYMYEYQYYPSFSSPQRPKHVVGDHADDLYSVFGAPILRDGASEEEIKLSKMVMKFWANFARNGNPNGRGLPHWPQYDQKEEYLQIGATTQQSQRLKAEEVAFWTQLLAKRQPQPHHNEL
What is the function of this protein?
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs.  Hydrolyzes retinyl esters (PubMed:12230550).  Hydrolyzes p-nitrophenyl butyrate (PNPB), triacylglycerol and monoacylglycerol.  Shows higher activity against PNPB, a short-chain fatty acid ester, than against triolein, a long-chain fatty acid ester.  Shows no detectable activity against diacylglycerol, cholesterol ester or phospholipids.  May play a role in adipocyte lipolysis (By similarity).
What are the official names of this protein?
Liver carboxylesterase 1F, Carboxyesterase ES-4, Kidney microsomal carboxylesterase, Microsomal palmitoyl-CoA hydrolase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Lipid droplet. Cytoplasm, cytosol. Endoplasmic reticulum. Microsome.
Protein: SYY_CHLMU
Sequence: MQQLIDSLQKRGILDNSSAGLESLTAPVSAYLGFDPTAPSLHIGHWIGICFLRRLSAYGITPIALVGGATGMIGDPSGKSVERSLLDQEQVLDNSKKIEVALANYLPDIRIVNNADWLGSLSMVDFLRDIGKYFRLGSMLAKDVVKQRVYSEEGISYTEFSYLLLQSYDFAHLFKHHGVVLQCGGSDQWGNITSGIDYIRRKGLGQAFGLTYPLLTDSKGKKIGKTESGTVWLDPELTSPYELFQYFLRLSDQEIPKIARMLTLLDDDEVLALDKRLENDPQAVKRYVAEVIVKDVHGAEGLAQALATTESFFANKGKNITESELAALVQSGVGINVARADVIGKRWLDVVVQLGFCSSKGEARRLIQQRGLYVNQEPLIDEQSVLDGTYLCFDRYILLSQGKKKKQVIDLN
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUX2_CONCL
Sequence: SLCDKPHHNCIDGQTCYHTCCQNGLKCVRYP
What are the official names of this protein?
Conotoxin Cltx-2, CalTx-2.
What are the subcellular locations of this protein?
Secreted.