PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_ALKMQ
Sequence: MGKVIGIDLGTTNSCVAVLEGGEPVVIPNSEGNRTTPSVVAFGKDGERIVGEPAKRQAVVNPEKTIISIKTHMGSDHKVAIDDKNYTPEDISAMILQKIKADAEAYLGEAVTDAVITVPAYFTDSQRQATKDAGKIAGLNVRRIINEPTAASLAYGLDKTDEHQKILVYDLGGGTFDVSILELGDGVFEVLATNGNNNLGGDDFDQALMDYIAEAFKKQEGIDLRKDKMSLQRLKEASEKAKQELSSTMTSSINLPFITATNEGPKHLNMDITRSKFDEITSHLVEKTMGPMRSALKDAGLSASDINKIILVGGSTRIPAVQQAVKKITNQDPHKGVNPDECVAVGAAIQAGVLTGEVKDVLLLDVTPLSLGIETLGGVFTRLIERNTTIPSKKSQTFSTAADNQPAVDIHVLQGEREMAAGNVSLGRFELSGIPPAHRGIPQIEVTFDIDANGIVNVSAKDLGTGKEQKITITASTKLSDEEIEKKIKEAEEHAEEDKMQKEKIEVRNQADSLVYQIEKTLKESEGKIDKEEEGKVTAELEKLKKAVESDIVEDMKKAIEDVNTVFHAISQKLYEQAAQAQEAEGQEQAGDDNIVDAEYEEVKDEETQGEDEK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RLMN_CHLAA
Sequence: MHYAMEQRCLYDYNLSELTELLQSWGEPAFRARQLYRHLYVNLARQVDQMTDLPLALRSRLAEIPFSTLRCEQVQIGDNGMTRKALFRLPDGAVVETVLMVYPDRSTVCVSTQAGCGMGCVFCATGQLGLLRNLSSGEIVAQAIWASQELRAMGMAGPTGRVSNLVFMGMGEPFANYDRWWQAVERLHDPQGFNLGARSMTVSTVGLVKGIERLANERLPINLAISLHAPDDALRSELMPVNRRYPIADLMAATRNYIAKTRRRVSFEYVLLQGKNDHPHQAIALARLLRHSAPRGPLLFHVNLIPWNPVPGTPLGRSEWERVTTFQQILTDYGIPCTVRVERGVEIAAACGQLAGRHSVPLNTVEQEIPARNVTG
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_METS5
Sequence: MIVLFVDFDYFFAQVEEILNPSLKGKPVVVCVYSGRTKDSGAVATSNYEARKLGIKAGMPIIKAKEIGKDAVFLPMRKEVYQQVSRRVMNIISGYGDKLEIASIDEAYLDITRRVKDFDEAKELARKLKAEVLEKERLRVTVGIGPNKVVAKIIADMNKPDGLGIIYPEEVKDFLYNLDISKVPGVGKITEEILRKVGINRLGDVINKSGELVNLVGKSKANYLLSLANNTYHDPVESREITHRGRYVTLPENTRDLNRILPSLKRSIEEAYSKVDGIPMEIYVVAIMEDLDIVSKGKSFKFGVSQDRALSVAQELLNKILESDKRKLRRVGVRLGKITKSSTLEDFLH
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_HALWD
Sequence: MQTALVILDGWGLGDHDRRNAVQTASTPTFDRLIEKGANGTLDVSGRQVGLPAGQMGNSEVGHLNIGAGQVVKQAYTRVEDAIDNGSFQTNAAINAAFNHAVATNGRVHFMGLLSDGGVHSEQEHLHALIELAGDRNIDAITHVFTDGRDTNPHSSEQYLTTLEEVIHTHGTGDIATVSGRYYAMDRDKNWTRTRMSYDAIVNRTAEHTTSTALEAVSESYDRGDTDEFIEPTLIDNTPAVEDGDAVFVFNFRPDRVRQLVRMLADIDPAWSFETDPPTTELATMAQYDETFSLPVAFPPNEQHDTLGEVIATAGLTQLRIAESEKYAHVTYFLNGGREIAFEDERREIIKSPDVSTYDQQPSMSSNEVTDTAIEQINTTDPDVLILNYANPDMVGHTGDFTAAIEAIESVDTQLDRLLETIYAAGGHVIVTADHGNADNMGTAANPHTAHTTNPVPIVYTRPDGNGDGDTIRDGGSLCDIAPTVLELLSVEQPAAMTGSSLIE
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: CNOT6_HUMAN
Sequence: MPKEKYEPPDPRRMYTIMSSEEAANGKKSHWAELEISGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPLTQDILNLYQEPDGTRRLLNYLLDNLSGTAKRITTEQPPPRSWIMLQEPDRTRPTALFSVMCYNVLCDKYATRQLYGYCPSWALNWDYRKKAIIQEILSCNADIVSLQEVETEQYYSFFLVELKERGYNGFFSPKSRARTMSEQERKHVDGCAIFFKTEKFTLVQKHTVEFNQLAMANSEGSEAMLNRVMTKDNIGVAVLLELRKESIEMPSGKPHLGTEKQLILVANAHMHWDPEYSDVKLVQTMMFLSEVKNIIDKASRNLKSSVLGEFGTIPLVLCADLNSLPDSGVVEYLSTGGVETNHKDFKELRYNESLTNFSCHGKNGTTNGRITHGFKLQSAYESGLMPYTNYTFDFKGIIDYIFYSKPQLNTLGILGPLDHHWLVENNISGCPHPLIPSDHFSLFAQLELLLPFLPQVNGIHLPGRR
What is the function of this protein?
Poly(A) nuclease with 3'-5' RNase activity.  Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.  Additional complex functions may be a consequence of its influence on mRNA expression.  Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm.  In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA.  The increase of ligand-dependent ESR1-mediated transcription is much smaller, if any.  Mediates cell proliferation and cell survival and prevents cellular senescence.
What are the official names of this protein?
CCR4-NOT transcription complex subunit 6, CCR4 carbon catabolite repression 4-like, Carbon catabolite repressor protein 4 homolog, Cytoplasmic deadenylase.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
Protein: SYK_SALPC
Sequence: MSEQNAQGADEVVDLNNEMKARREKLAALREQGIPFPNDFRRDRTSDQLHAEFDAKEAEELEALNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGLQDQEARYRQRYLDLISNDESRNTFKTRSKILAGIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDVLGTTQVPYGDEVFDFGKPFEKLTMREAIKKYRPETDMADLGNFDSAKAVAESIGIHVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVNAKAAGDDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MATRX_HRSS2
Sequence: METYVNKLHEGSTYTAAVQYNVLEKDDDPASLTIWVPMFQSSMPADLLIKELANVNILVKQISTPKGPSLRVMINSRSAVLAQMPSKFTICANVSLDERSKLAYDVTTPCEIKACSLTCLKSKNMLTTVKDLTMKTLNPTHDIIALCEFENIVTSKKVIIPTYLRSISVRNKDLNTLENITTTEFKNAITNAKIIPYSGLLLVITVTDNKGAFKYIKPQSQFIVDLGAYLEKESIYYVTTNWKHTATRFAIKPMED
What is the function of this protein?
Plays a crucial role in virus assembly into filaments and budding.  Early in infection, localizes in the nucleus where it may inhibit host cell transcription.  Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication.  During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer.
What are the official names of this protein?
Matrix protein, M protein.
What is the protein family that this protein belongs to?
Belongs to the pneumovirinae M protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Host nucleus. Host cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=In the cytoplasm, associates with inclusion bodies. During bud formation, associates at the inner side of the plasma membrane of infected cells.
Protein: TRMD_XANC8
Sequence: MRIDVISLFPEFIAQCAAFGVVGRAQERGLLELKGWNPRDHAQGNYRRVDDRPFGGGPGMVMLIEPLRACLEVAQAADARPAPVIYLSPQGRPLTQPLARELAQLPRMVLLCGRYEGVDERFLDQAVDMEISIGDYVLSGGELGAAVLVDVVTRLQDGVLNDAESAAQDSFEGPQGLLDCPHYSHPSSHAWGDVPEVLRSGNHGAIARWRRQQSLGRTWLRRPELLDEATLDKQDRRLLEEFRRELAPGDEK
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_STRP2
Sequence: MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLREYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFYKSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELNAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVERGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEAGREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKILFNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNIIAEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPETGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVITEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGSIQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDTDLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEGNEETTEVVVDTAVETVEETVE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: YCIB_LARHH
Sequence: MKFLSDLLPVLLFFAAYSLTGNIYLATGVAIVSTAAQVGISWFKHRKVEPMQWVSLALILVLGGLTLVLHDKRFIMWKPTVLYWLLGAGFLISDLAFRKNPIKAMMGKQIELPERLWAKLTFAWSGFFAFMGALNLFVAFNFSEAVWVNFKLFGGMGLMLVFVLAQGMVLSRYIQEKN
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FIN1_YEAST
Sequence: MSNKSNRRSLRDIGNTIGRNNIPSDKDNVFVRLSMSPLRTTSQKEFLKPPMRISPNKTDGMKHSIQVTPRRIMSPECLKGYVSKETQSLDRPQFKNSNKNVKIQNSDHITNIIFPTSPTKLTFSNENKIGGDGSLTRIRARFKNGLMSPERIQQQQQQHILPSDAKSNTDLCSNTELKDAPFENDLPRAKLKGKNLLVELKKEEEDVGNGIESLTKSNTKLNSMLANEGKIHKASFQKSVKFKLPDNIVTEETVELKEIKDLLLQMLRRQREIESRLSNIELQLTEIPKHK
What is the function of this protein?
Forms cell-cycle specific filaments between the spindle pole bodies of dividing yeast cells.
What are the official names of this protein?
Filament protein FIN1, Filaments in between nuclei protein 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle pole. Note=Nuclear during early bud formation, located at the spindle poles during late mitosis, very low abundance in resting cells.
Protein: TIG_ALIB4
Sequence: MEFNANRVDEANAVITATLTKDSIENNLEKVAKQAAKTMNVQGFRKGKVPVAVVKQRYADKLREDAEADGIRKILADGLKLLDIKNSDLIGEPSVTKFDKKDNGDIEVELSVACKPNIDLGDYKSLVPAVKAIEIDIKKIDDRLTEIAQSSAPLEKIARKRAVKDGDFAVIDFEGFVDGVAFDGGKAEKYPLQIGSGSFIPGFEEQVIGMKYEEQKDITVKFPESYQAKDLAGKEAVFKVTLHEIQERAKPELNDEFAQKMLPGQKDVTIDTLRDRVKEQMLAEDKAKYYRDELKPVFLETLVEKINFALPTSVIEQEINYALNNKIRTMTEEEINELKENANKVEDIRNELKEDAVNSVKATFIIDALAKAENVQVSDQEVTQVLYFEAMQMGQNPQDVIKQYQQAGYLPAIKMSMIEEKVISKLLDEKLGK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: HSP72_SCHPO
Sequence: MSKSIGIDLGTTYSCVGHFSNNRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPHNTIFDAKRLIGRKFDDPEVQSDMKHWPFKVISKDGKPVLQVEYKGETKTFTPEEISSMVLMKMRETAEAYLGGKVTDAVVTVPAYFNDSQRQATKDAGLIAGLNVLRIINEPTAAAIAYGLDRSNQGESNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDSRLVNHFIQEFKRKNKKDITGNARAVRRLRTACERAKRTLSSSAQASIEIDSLFEGIDFYTSITRARFEELCADLFRKTMEPVERVLRDSKVDKASVNEIVLVGGSTRIPRVQKLVSDFFNGKEPCKSINPDEAVAYGAAVQAAVLTGDTSEKTQDLLLLDVAPLSMGIETAGGVMTPLIKRNTTIPTKKSEIFSTYSDNQPGVLIQVFEGERARTKDCNLLGKFELSGIPPAPRGVPQIEVTFDVDANGILNVSALEKGTGKTQKITITNDKGRLSKEEIDRMVAEAEKYKAEDEAESGRIQAKNHLESYAYSLRNSLDDPNLKDKVDASDKETVDKAVKETIEWLDSNTTAAKDEFEAKQKELESVANPIMAKIYQAGGAPGGMPGAAPGAAPGAAPGAAPGGDNGPEVEEVD
What are the official names of this protein?
Probable heat shock protein ssa2.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN_STRPF
Sequence: MNEAIIQLDHIDITFHQKKRVIEAVKDVTVHINQGDIYGIVGYSGAGKSTLVRVINLLQAPTNGKITVDGDVTFDQGKIQLSAEALRQKRRDIGMIFQHFNLMAQKTAKENVAFALRHSSLSKTEKEQKVIELLELVGLSERADNYPAQLSGGQKQRVAIARALANDPKILISDEATSALDPKTTKQILALLQELNRKLGLTIVMITHEMQIVKDICNRVAVMQNGVLIEEGPVLDIFSNPKEALTQEFITTATGIDEALEKINQQDIVKHLPANALLAQLKYAGTSTDEPLLNSIYRQFEVTANILYGNIEILDHIPVGDMIVVLEGQAENILAAEKALHEAGVDVSILKRGA
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: AYR1_SCHPO
Sequence: MEAEKFVLITGCSEGGIGNALALKFHQEGFQVLATARQVERMDNLTKAGLQTLKLDVTDEDSVREVEQEVRKFTNGSLHYLINNAGAPCSAPAIDLDIEDVSKVMDVNFYGVIRMNKAFQHQLIRAKGTIVNVNSLVSYVPFAFNAAYNASKAALLAYSNTLRIELAPFGVQVTSIMTGGVQTKIQSKPLGTMTEAAIPENSIYYPYRKLILENRNPVEKFVTIEEFADAAYPQLVGRGRWYQLFKPGVRPAQIWAGYMSSAGRVGSMLPVEVFSMSVRLIVKLPSTAVWRDHTVD
What is the function of this protein?
Can convert acyl and alkyl dihydroxyacetone-phosphate (DHAP) into glycerolipids and ether lipids, respectively.  Required for the biosynthesis of phosphatidic acid via the DHAP pathway, where it reduces 1-acyl DHAP to lysophosphatidic acid (LPA).  Also has triacylglycerol (TAG) lipase activity.  Involved in the mobilization of the non-polar storage lipids triacylglycerols (TAGs) from lipid particles by hydrolysis of TAGs.  Lipolysis of TAG by AYR1 is essential for starvation-induced autophagy.  Forms an NADPH-regulated cation-selective channel in the mitochondrial outer membrane.
What are the official names of this protein?
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase, ADR, 1-acyl DHAP reductase, Acyl/alkyl DHAP reductase, Acylglycerone-phosphate reductase, Triacylglycerol lipase ayr1, TAG lipase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Lipid droplet. Cytoplasm. Vacuole. Endoplasmic reticulum. Golgi apparatus. Mitochondrion outer membrane.
Protein: DAD1_RAT
Sequence: MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity.
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, Oligosaccharyl transferase subunit DAD1, Defender against cell death 1, DAD-1.
What is the protein family that this protein belongs to?
Belongs to the DAD/OST2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TRHO_XYLF2
Sequence: MVIINTAAYHFVSITQPQTLADQIRAHGEIAGLKGTVLIANEGINLFLAGEKEAINAFYAWLCADVRFAALHVKYSVSAYKPFARFKVKVRPEIISFRRGDISPLQVRAPGVSAHTLRDWLRRGCDDNGRRLVMLDARNQQEIAYGTFSGAMTLPITKFTGFPGALAHYRDLLSDATVVSFCTGGIRCEKAVLWMRADGMDNVLQLEGGILGYFEQVGGEGYDGRCFVFDKRVALDPQLRPLYDMRVVASFARSEIS
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: ALG12_SCHPO
Sequence: MTSKESICWYLANILLVTCIGYYSYKTPFTKVEESFAMQAIHDIQTYRWDLSKYDHLEFPGAVKRSFIPSLFIAVLSYIPSWFVNPLLAARWTIGYLSWESMNSVSCSISKRFGTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKNNYYGSISILVFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFYYYFVRLPWLFLNPTTLLFLLISFVYIKPARLLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAASAIGASLCFNASKFGKKIFEILRLMFFSGIIFGFIGSSFLLYVFQYAYPGGLALTRLYEIENHPQVSVHMDVYPCMTGITRFSQLPSWYYDKTEDPKMLSNSLFISQFDYLITEDPESYNDTFDVIESVNSNTKIPILPKWLSNHIPREISIRNPAQPVYILANKKARATKPAAVDDYSSFIGHKVDEIKLWPPIYRVVSPDTLLTRDYREDRLNFFIDKDRILTHITQG
What is the function of this protein?
Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
What are the official names of this protein?
Probable Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase, Asparagine-linked glycosylation protein 12 homolog, Dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase, Mannosyltransferase ALG12 homolog.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 22 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CR020_HUMAN
Sequence: MINLHRLCIIHVVATLLSTLLSLISVAISATCKDEKGKQEMETGQQPSGLSATLTKVKCAKRQKTVVRVRFYMLSMKNKACRKNLSKGYNQRPEGSKEESHMVVKEKRKGDH
What are the official names of this protein?
Putative uncharacterized protein encoded by LINC00305.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH_VIBA3
Sequence: MTKQVEIFTDGSCLGNPGPGGYGIVLRYRKVEKTLAEGFTLTTNNRMEMLAAVVALQALKEPCSVILTTDSQYVRQGITQWIHNWKKRDWKTADKKPVKNADLWQRLDKETARHSVDWRWVKGHAGHRENEMCDDLARSAAENPTQEDTGYQPS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y068_OSHVF
Sequence: MILTIILYTLLFSTCSAQSVHTMPEAVSRLNWGVMFNRGPTIMNGITKYRHTFEVKVPQLVYTPIVHMKCDTDYLKVLHCEAINDLIDSINGQVEPLITELKTRIATWMNPIPNVDTLTLPETQGRRGRRRREATLGPDYCKKINDPNYEGGGGGFLSSVGNFFSSLMGSPTWDDIKIIDKHICQLADVVDLNKEKIVQLGTEFATFSKAANNRMDALEDGMKNINTRVTETNLLLEKLSTEVTGALTQLENEIKMSMAGTNLLFRVQKQLYKFQEQINTMSATVEDFGNGINVLLSGRLAPQLVSVDSVKYVIDIISEKLTQQGGETRLVDQNPALYYLLNNVVFTKSEKLNSLYIMVSFPIYSIGGLMATYRLDKTYISIKEDVVSSTQIADLPDFLAVTPDGLYYSEFSTSEISSCTGDVIKSCKNERALQSFTQMTCAAALYKDDSTKILELCDIRYDQITVPSTAIKITDDTYMIHSSKVGTGHQWTISCPLIPNYVSTTMDACNACVVQVSCGCELIAPGEFYIPLQLTGCSKVLSSYIPHIEPKFPVNLPVLYAYFDDSVLNEINGDKLLNYKWKLDIPSIAPLEEEWSQSVERSQKYSSSLKKLLEETKANRKVYASKATAMLKKATDFTDLKLSKIKTLSDTFKDLSWLTKFGTGGGIAGVTIGLLLPILAIVFSCYVFCKRRV
What are the official names of this protein?
Putative transmembrane protein ORF68.
What are the subcellular locations of this protein?
Host membrane; Single-pass type I membrane protein.
Protein: HPPD2_ASPFU
Sequence: MTVSKKVEENIFASKLGPEYVGFDHITWYVGNAKQAASYYVTRMGFKQIAYRGPETGSRSVVSHVISNGQAIFVLTSPIRSMAGTGAYDDDPDVTKADRRLLEEIHNHLIKHGDGVKDVAFRIEGDIEAVWKRAVDHGAAPVAAPTTLKDDRHGSITLATIGTYEDTVHSLINRHDYSGPFLPGYEVVTDDDPINRLLPSIDFIEIDHCVGNQPWNGVDPIVKYYEDCLNFHRYWTVDDLNMCGEYSAMRSIVVASPNEVIKMPMNEPAQGKKKSQIEEFVNYYNGAGVQHIAFRTHDIVTAVTRLRERGVSFLEVPSAYYSDLRQRLSHTGLTLEEDIAVLEKLHILVDFDEKGYLLQIFSKHVLDRPTVFIEVIQRNNFDGFGAGNFKSLFEAFEREQARRGNL
What are the official names of this protein?
Probable 4-hydroxyphenylpyruvate dioxygenase 2, 4HPPD 2, HPD 2, HPPDase 2.
What is the protein family that this protein belongs to?
Belongs to the 4HPPD family.
Protein: RL18_CLOTE
Sequence: MFKKQSRQKGREKRHLRIRKNIFGTPEMPRLSVYRSEKNIYAQIIDDLNGVTLVAASSLDKEFDAKGSNKDGAKLVGELVAKRAIEKGVTKVVFDRGGYIYHGRVQELAEGAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: EFP_SHISS
Sequence: MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQIGEVIKVDTRSGEYVSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSE5_SCHPO
Sequence: MNSALKAIIELCIEEDLLPKSLDVLEYLLSTTSIPIPACYIRMCITLLVHPEYPTSSNIQESCNWILQQVVENRSKINFDAWSFENDLSDNDMPKENYLKIFSNQCLFTQDVDYWDLIAYMSSRPPDLERWMSLMDIWLRILEIDAEENGSALMKKYMGEDLCELQDAIRICFSCFTLPQQTMESPFATSMSKAPAKTESRGSNSFEGTSRLANLGAKLLCLIWAMLPKGRFFVVHLTDAFHFLSKLDERFSKLNAKQQDLFFGNLGASNLRYCLSQYILMKGIGIGINIRHTRCEFTKQLTQLLPTSLPKNKIRQKLHLRAWVSFLGSALRESDRNFDKELFYTTLKQLYTMYQQTELVGIDRPMAILKDMLVLLDISKKLSLDKIV
What is the function of this protein?
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage.  Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.  May prevent formation of excessive Holliday junctions or assist in their resolution.
What are the official names of this protein?
Non-structural maintenance of chromosome element 5, Non-SMC element 5.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Chromosome.
Protein: RS24_METKA
Sequence: MEVEILDQRDNPLLYRKEVKFVVRHEDSGTPQKSEVLRKLAAILDVDKEVVLIDRMESEFGKRETKGYAKIYKSMEHLEDIEPEHMVERHKKVLEELESESEESEESESEESEEEE
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.