PharMolix/UniProtQA huggingface dataset:
Protein: PNP_CLOTE
Sequence: MSHVLETDIAGRTLKVEYGKVGMLSNCAILVSYGDTVVLINANASKEPRDGIDFFPLSVEYEERLYSVGKIPGGFIKREGRPTENAILHARAIDRPLRPLFPKGYRNDVQIVCTVLSVESDNQPDILAMNGASLALCLSSIPFTTPVANVSVGLINGDFILNPTQSQREESILNLTVSATKERVMMIEAGAEEVDEDTMYNAIRFGFEQCQKIVEFQEEAMRRFGKEKVEPVLYLVDKDIEKEVREFAFPMVKEAMYISDKDLRNEKIDEVKEKVKEEFEEKYPENDSDISEALYKMQKEVVRNMILREKRRPDERAFDEIRKISCEVGLLPRTHGTGLFTRGLTQVMTAATIGPLADVQILDSIEDEEFKRYMHHYNFPSYSVGETRPLRGPGRREIGHGALAEKALEPLIPSEEDFPYTIRLVSEVLSSNGSTSQASVCGSTLALLDAGVPIKRPAAGIAMGLVTNDDLTEEKILTDIQGIEDFFGDMDFKVAGTEKGITALQVDTKISGLSDNCIKETLIKAKDARMYILGKIKECIPEHRAELSPYAPRVYTMTIAPEKIRDVIGAGGKTINKIIGETGVQIDIKEDGKIYVMSSDSVGANRALKMINDLTKDVEAGEIYLGKVTRTTNFGAFVEILPGKEGLVHISKLDFTRVNKVEDVVSVGDEILVKVTDIDDQGRINLSRRDAIKKEEDEKTKENNH
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAM1B_DANRE
Sequence: MEDGGLGMDAELGADSARRKMEAAGEALEIVPLEMYDSARAKIAANLRWLFAKAFGIDHIPEDLRDPFYRDQYEQEHIKPPVIRLLLSCELYCRVCALILKGDQVASLQSHQSVIQALSRKGIYVMEDDDTPVTDSDLTCQPIKMSSHIPMIDALMMAYTVEMISIEKVVSCVKRFSTFSASKELPFDLEDAMIFWINKVNLKMREITEKEHKSKQHLLESPSHQKSPSKWYWKLVPVRYRRDHASGRQLPYFQMLEDLIRDVCDGAALLTVVHYYCPELMKLDDICLKEVTSIADSLYNIQLLKEFANEYLNKSFYLTLEDLLYAPPVLKHNVMVFIAELFWWFEIVKPEFVQPRDVQEFKDARAVSQPKSARPTVPISNATKRSFLVSPGAADPVLPVQNSPEVCNSNKGSSGFSPSHPLLPLRQRQKKAQPAEESTACRNRSNSLTQEGHPRGSVAWSDKRQRPLSQLNRYVLHSATDSDADLASGDSVSLTCSISEDSLASTVTPKHQSHPGQGSVRRINGHSLLGNVNMDEEEELVAIARADPSKNDITLTNSEDTERQGVTPGAKSIWGRQEDASSDSRTASFFLEPLMPAVLRPAKEKSISLNKEEESGEGRQRGSTRRVAGAESAASSTRRRPPQTLNRTFTPNTSSEFETTIEPKSSEFVPPAPGQMQAFRPLVTSSVEPSSAERSPGFYLHSSVTEEKRPVQAWDAHPGTSDIETVETIEEQDAELTKELHPDKKQHFEEEVESAKLREDMNVKEHEDKDGGSRCSSPGQQSQVSSVASGSIRMTSFAERKMQRFGSNQDIRSSTSSSQRTTPDGSESCPLPLTSWRMKRDQSPTPQNKDNANMLASELVQLHMQLEEKRRAIESQKKKMEILTARQRLKLGKAAFLHIVKKGKSDTLPQPTKSEFYLKEGQKLNEEKEVSSKDDTCVDALRDRSKEAEEPEKASCEWAGGGTVSSSPLDVEEEVDLNECNRSIELLNEAIGSIQQQMMQLSLQQEMLMKQNIQSPTSATSPLANDQINTSEPRVRASIHFVEPSGSPVVRKPPKLSSARPRSKPSELLLGKEHSKGQKSSTPTPTDSPSARSIQGGRTPKAESQDFVQSSVRSESFNKDKGNHKGTTFHLNDEANMRMVSREPSSVALGVTFEESMSLRDTETTFDDGTARDNLISSEDISRGKANLIEVDLSDLAANTDDESTNALDVTADGSDGEKKSGMGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARLRKQQLEAESEQKRDETRRKAEEERIRKEEEKARRELIKQEYLRKKQLELCEEQEQPQPKPKTKPKKQRLKSVVKEEPSIDPLPKCPAANENLISAQSGSSLSLASVATTEPDSVNSGGAGSQRGESVESFPGLSRNSSRTTERDWDNGSTASSITSTSMAEYTGPKLFKEPSAKSNKPIIHNAISHCCLAGKVNEPQKNSILEELERCESNHLMILFRDSGCQFRALYSYFPDTEEIHKLTGTGPKSITKKMIDKLYKYSSDRKQFTVIPAKTVSVSVDALTIHNHLWQAKRPAGPKKSAK
What is the function of this protein?
Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization.  Specifically recognizes growing microtubule minus-ends and stabilizes microtubules.  Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization.  In contrast to camsap2 and camsap3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation.  Through interaction with spectrin may regulate neurite outgrowth.
What are the official names of this protein?
Calmodulin-regulated spectrin-associated protein 1-B.
What is the protein family that this protein belongs to?
Belongs to the CAMSAP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Note=Associates with the minus-end of microtubules. In contrast to camsap2 and camsap3, does not form stretches of decorated microtubule minus-ends.
Protein: CLPP_FUSNN
Sequence: MYNPTVIDNNGKSERAYDIYSRLLKDRIIFVGTAIDETVANSIIAQLLYLEAEDPEKDIIMYINSPGGSVTDGMAIYDTMNYIKPDVQTVCVGQAASMGAFLLAAGAKGKRFALENSRIMIHQPLISGGLKGQATDISIHANELLKIKDRLAELLAKNTGKTKEQILRDTERDNYLSSEEAVNYGLIDSVFRR
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPE_KLEP7
Sequence: MEQFECINVEEAHQKLHQQTAVLVDIRDPQSYAMGHTPGAFHLTNDTLGAFMRDNDFDTAVMVMCYHGNSSKGAAQYLLQQGFDKVYSVDGGFDAWHRHFPAEVARGTF
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SOTI_DROSE
Sequence: MDVLHAHDLYDEQLIDRVGDAVNEDAGDDLDTLVDGQQQQQRVGFNRQMDILLDAPQEPPLGVFPAQGGPNGPPRLRKKRSFYTMTKPTPPCQSQEPEMCLLMASVTRAMRHVREDQRGEYFANYLVENMTSQNYPNGVGLPQHWGQL
What is the function of this protein?
Post-meiotically transcribed gene that has a role in late spermiogenesis; required for actin cone progression during spermatid individualization.
What are the official names of this protein?
Male-specific protein scotti.
What is the protein family that this protein belongs to?
Belongs to the male-specific scotti family.
Protein: APT_STRP8
Sequence: MDLTNYIASIKDYPKAGITFRDISPLMADGKAYSYAIREIAQYACDKDIDMVVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPRDVVSADYEKEYGLDTLTMHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGIVAGCAFLIELEGLNGRHAIRNYDYKVLMQFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBTP2_MOUSE
Sequence: MIPVSLLVVVVGGWTAVYLADLVLKSSVYFKHSYEDWLENNGLSISPFHIRWQTSIFNRAFYSWGRRKARMLYQWFNFGMVFGVIAMFSSFFLLGKTLMQTLAQMMADSPSPYSSSSSSSSSSSSSSSSSSSLHNEQVLQVVVPGINLPVNQLTYFFAAVLISGVVHEIGHGIAAIREQVRFNGFGIFLFIIYPGAFVDLFTTHLQLISPVQQLRIFCAGIWHNFVLALLGILALVLLPVILLPFYYTGVGVLITEVAEDSPAIGPRGLFVGDLVTHLQDCPVTNVQDWNECLDTIAYEPQIGYCISASTLQQLSFPVRAYKRLDGSTECCNNHSLTDVCFSYRNNFNKRLHTCLPARKAVEATQVCRSNKDCKSGASSSFCIVPSLETHTRLIKVKHPPQIDMLYVGHPLHLHYTVSITSFIPRFNFLSIDLPVIVETFVKYLISLSGALAIVNAVPCFALDGQWILNSFLDATLTSVIGDNDVKDLIGFFILLGGSVLLAANVTLGLWMVTAR
What is the function of this protein?
Zinc metalloprotease that mediates intramembrane proteolysis of proteins such as ATF6, ATF6B, SREBF1/SREBP1 and SREBF2/SREBP2.  Catalyzes the second step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2: cleaves SREBPs within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached.  Mature N-terminal SREBP fragments shuttle to the nucleus and activate gene transcription.  Also mediates the second step in the proteolytic activation of the cyclic AMP-dependent transcription factor ATF-6 (ATF6 and ATF6B).  Involved in intramembrane proteolysis during bone formation.
What are the official names of this protein?
Membrane-bound transcription factor site-2 protease, Endopeptidase S2P.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50A family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cytoplasm.
Protein: Y369_LISMO
Sequence: MGRKWANIKEKKASKDKTNSRIYAKFGIEIYVAAKSGDPDPHSNQKLRFVIERAKTYNVPKHIIDRAIEKAKGTGDETYSELRYEGFGPNGSMIIVDALTNNVNRTASDVRAAYSKNGGNMGVSGSVAYMFDNTAIFGVEGKDADELLELLMEADIDVRDILDEDGQAIIYAEPEDFHKVQEGLKAAGIEEFTVAEIEMIPQNDIQLSGEDLEKFERLIDALEDLEDVQKVYHNVELED
What are the official names of this protein?
Probable transcriptional regulatory protein lmo0369.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family. YeeN subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF1_GEOKA
Sequence: MFDRLEAVEQRYEKLNELLMDPDVINDPKKLRDYSKEQADLEETVQTYREYKSVREQLAEAKAMLEEKLEPELREMVKEEIGELEEREEALVEKLKVLLLPKDPNDEKNVIMEIRAAAGGEEAALFAGDLYRMYTRYAESQGWKTEVIEASPTGLGGYKEIIFMINGKGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVACLPEMEEIEVEINEKDIRVDTFASSGPGGQSVNTTMSAVRLTHIPTGIVVTCQDEKSQIKNKEKAMKVLRARIYDKYQQEARAEYDQTRKQAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQVLDGHLDEIIEALILDDQAKKLEQANDAS
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_CORGL
Sequence: MDFDEVLEKYDPVMGLEVHVELGTETKMFSASSAHFGAEPNSNVDPVSLGLPGALPVVNAKGVEWAIKIGLALNCSIAESSRFARKNYFYPDQPKNYQISQYDEPIAYDGYLDVVLEDGTEWRVEIERAHMEEDTGKLTHLGGTSGRIHGATASLVDCNRAGVPLIEVVTKPIEGAGARAPEIAKAYVSALRDLVKALGVSDGRLDQGSMRVDANLSLRPIGQEEFGTRTETKNINSLKSVEQAITFEMQRQAQVLDDGGVIDQETRHYQEADGSTSKGRPKETAEDYRYFNDPDLPPVIAPREWVEEIRATLPELPWVRRARIQEEWKLSDAEMRDLINANALDLIIETVEAGTTPDEARAWWVSYISQKANESGVELDALGVAPAHVARVVALVSEGKLTNKLARQAIDGVIAGEGDVDAVVAARGLEVVRDDGAIEKAVDDALAANPDIVEKYRAGNTKVTGAIVGAVMKATRGKADPAQVNQLIAKKLA
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: ISPE_RHILW
Sequence: MPEAGLAEAFGVTEEARAKINLALHVTGQRADGYHLLDMLVTFADCGDRLGFLPAQTDAFTLSGRFGEMLAGDGGTNLVLRARDLLREQFGALAFPVHIHLQKNLPVASGIGGGSADAAAALRGLMRLWGMSLPVEALASLALKLGADVPMCLESRPLIARGIGEEIEAVPDLPAFAMVLANPLKGVSTPEVFRRLTTKNNSALSLAPGLSGSAGWLAVIDAARNDLEPPARQLVPEIAVISAMLQARGALLTRMSGSGATCFGIFASMAEAQDAAAALHGERPDWYFQATETVSGGM
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TI16A_XENLA
Sequence: MAKYLAQIVVMGMQVVGRAFTRALRQEFAASKVAAEARGRAGTESAAVSSLSGISLQEAQQILNVSKLTPEEIQKNYEHLFKVNDKGLGGSFYLQSKVVRAKERLDQEMEIQSKTHKPKEETTQT
What is the function of this protein?
Regulates ATP-dependent protein translocation into the mitochondrial matrix.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit tim16-A, Presequence translocated-associated motor subunit pam16-A.
What is the protein family that this protein belongs to?
Belongs to the TIM16/PAM16 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: S7A13_MOUSE
Sequence: MAMDSKKEIRLKRELGYFWGTNFLIINIIGAGIFVSPKGVLQHSSMNVGVSLCVWAVCAVLTLTSALCSAEIGITFPYSGAHYYFLKRCFGPLVAFLRLWTSLFLGPGLIASQALLLAEYGVQPFYPSCSAPILPRKCLALAMLWIVGILNSRGVKELSWLQTVSSVLKVGILGVISLSGLFLLVRGKKENVQRLQNAFDAEFPEVSQLIEAIFQGYFAFSGGGCFTCIAGELKKPSKTIPRCIFTGLPLVTVVYLLANISYLTVLTPQEMLSSDAVALTWTDRVIPQFTWTVPFAISASLFINLVINVLETSRVLYIASENGQLPLLFCALNVHSSPFIAVLLIISMASILIVLTNLIDLINYLYFVVSIWTALSIIGILKLRYQEPNLHRPYKVFLPFTFIALGITLSLVLIPLVKSPKLHYIYVFLFLLSGLVFYVPLIHFKVKFVWFQKLTCYLQLLFNICIPDVSDDHIHEES
What is the function of this protein?
Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner.
What are the official names of this protein?
Solute carrier family 7 member 13, Sodium-independent aspartate/glutamate transporter 1, X-amino acid transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VP35_EBORR
Sequence: MYNNKLKVCSGPETTGWISEQLMTGKIPVTDIFIDIDNKPDQMEVRLKPSSRSSTRTCTSSSQTEVNYVPLLKKVEDTLTMLVNATSRQNAAIEALENRLSTLESSLKPIQDMGKVISSLNRSCAEMVAKYDLLVMTTGRATSTAAAVDAYWKEHKQPPPGPALYEENALKGKIDDPNSYVPDAVQEAYKNLDSTSTLTEENFGKPYISAKDLKEIMYDHLPGFGTAFHQLVQVICKIGKDNNLLDTIHAEFQASLADGDSPQCALIQITKRVPIFQDVPPPIIHIRSRGDIPRACQKSLRPAPPSPKIDRGWVCLFKMQDGKTLGLKI
What is the function of this protein?
Plays an essential role in viral RNA synthesis and also a role in suppressing innate immune signaling.  Acts as a polymerase cofactor in the RNA polymerase transcription and replication complexes (By similarity).  Serves as nucleoprotein/NP monomer chaperone prior to the formation of the large oligomeric RNA-bound complexes (By similarity).  Regulates RNA synthesis by modulating NP-RNA interactions and interacting with DYNLL1.  VP35-NP interaction controls the switch between RNA-bound NP and free NP and thus the switch between genome replication and genome packaging into the nucleocapsid.  Prevents establishment of cellular antiviral state, thereby suppressing host DC maturation.  Acts by inhibiting host RIGI activation both by shielding dsRNA from detection and by preventing PRKRA binding to RIGI.  Blocks virus-induced phosphorylation and activation of interferon regulatory factor 3/IRF3, a transcription factor critical for the induction of interferons alpha and beta.  This blockage is produced through the interaction with and inhibition of host IKBKE and TBK1, producing a strong inhibition of the phosphorylation and activation of IRF3.  Also inhibits the antiviral effect mediated by the host interferon-induced, double-stranded RNA-activated protein kinase EIF2AK2/PKR.  Increases PIAS1-mediated SUMOylation of IRF7, thereby repressing interferon transcription (By similarity).  Also acts as a suppressor of RNA silencing by interacting with host DICER1, TARBP2/TRBP and PRKRA/PACT (By similarity).  As a dimer, binds and sequesters dsRNA contributing to the inhibition of interferon production (PubMed:20018665).
What are the official names of this protein?
Polymerase cofactor VP35.
What is the protein family that this protein belongs to?
Belongs to the filoviridae polymerase cofactor VP35 family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: TYSY_BIFLO
Sequence: MPYEDLVRKILTEGTLKSDRTGTGTISLFGQQMRFDLSKYFPLLTTKTVFFKGLAYELLWFLKGSSNINWLLEHNVHIWDEWADENGDLGPVYGVQWRSWPAPTPEDPNRTIDQISNVLDLIKHHPDSRRMIVSAWNPAEVEKMALPPCHALFQFYVADDKLSCQLYQRSCDMFLGVPFNIASYSLLTMMMAQQAGLKPGEFVWTGGDCHVYDNHVDQFLEQLGRKPYPYPTIEIRKADSLFDYQYEDFKVVGYQHHPTIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_CMVNT
Sequence: MAFSAPTFSLANLLNGSYGVDTPEEVERVRSEQREEAAAACRNYRPLPAVDVSESVTEDAHSLRTPDGAPSEEVSVEFVTYGAEDYLEKSDDELSVAFETMVKPMRIGQLWCPAFNKCSFISSIAMARALLLAPRTSHRTMKGFEDLVAAIYTKSDFYYDEECEADDIQIDVSSRDVPGYSFEPWSRTSGFEPPPICEACDMIMYQCPCFDFNALKKSCAERTFADDYVIEGLDGVVDNATLLSNLGPFLVPVKCQYEKCPTPTVAIPPSLNRATDRVDINLVQSICDSTLPTHSNYDDSFHQVFVESADYSIDLDHVRLRQSDLIAKIPDSGHMIPVLSTGSGHKRVGTTKEVLTAIKKRNADVPELGDSVNLSRLSKAVAERFFISYINGNSLASSNFVNVVSNFHDYMEKWKSSGLSYDDLPDLHAENLQFYDHMIKSDVKPVVSDTLNIDRPVPATITYHKKGITSQFSPLFTALFERFQRCLRERIILPVGKISSLEMAGFDVKNKHCLEIDLSKFDKSQGEFHLMIQEHILNGLGCPAPITKWWCDFHRFSYIRDRRAGVGMPISFQRRTGDAFTYFGNTIVTMAEFAWCYDTDQFEKLLFSGDDSLGFSVLPPVGDPSKFTTLFNMEAKVMEPAVPYICSKFLLSDEFGNTFSVPDPLREVQRLGTKKIPYSDNDEFLFAHFMSFVDRLKFLDRMTQSCIDQLSLFFELKYRKSGAEAALMLGAFKKYTANFQSYKELYYSDRRQCELINSFSCVELRIERSSSTKQRKKKDGIERRRSDKRRTPTGSYGGGEKTETKVSHEESTGTRSQKSQREGAFKSQIVPLPTILSGGWSGTDRAPPCEHGGIIRI
What is the function of this protein?
RNA-dependent RNA polymerase which replicates the viral genome composed of 3 RNA segments, RNA1, RNA2 and RNA3.
What are the official names of this protein?
RNA-directed RNA polymerase 2a, protein 2a.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: RLMH_PSE14
Sequence: MRLRLIAVGSRMPKWVEEGWHEYAKRMPSELALELVEIPLNTRGKNADVARFIRQEGEAMLAKVQPGERIVTLEVHGKPWSTEQLAVELDRWRLDARTVNLMVGGPEGLAPEVCARSEQRWSLSPLTLPHPLVRILIGEQMYRAWTVLSGHPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFOR_DESAF
Sequence: MGKKMMTTDGNTATAHVAYAMSEVAAIYPITPSSTMGEEADDWAAQGRKNIFGQTLTIREMQSEAGAAGAVHGALAAGALTTTFTASQGLLLMIPNMYKISGELLPGVFHVTARAIAAHALSIFGDHQDIYAARQTGFAMLASSSVQEAHDMALVAHLAAIESNVPFMHFFDGFRTSHEIQKIEVLDYADMASLVNQKALAEFRAKSMNPEHPHVRGTAQNPDIYFQGREAANPYYLKVPGIVAEYMQKVASLTGRSYKLFDYVGAPDAERVIVSMGSSCETIEEVINHLAAKGEKIGLIKVRLYRPFVSEAFFAALPASAKVITVLDRTKEPGAPGDPLYLDVCSAFVERGEAMPKILAGRYGLGSKEFSPAMVKSVYDNMSGAKKNHFTVGIEDDVTGTSLPVDNAFADTTPKGTIQCQFWGLGADGTVGANKQAIKIIGDNTDLFAQGYFSYDSKKSGGITISHLRFGEKPIQSTYLVNRADYVACHNPAYVGIYDILEGIKDGGTFVLNSPWSSLEDMDKHLPSGIKRTIANKKLKFYNIDAVKIATDVGLGGRINMIMQTAFFKLAGVLPFEKAVDLLKKSIHKAYGKKGEKIVKMNTDAVDQAVTSLQEFKYPDSWKDAPAETKAEPMTNEFFKNVVKPILTQQGDKLPVSAFEADGRFPLGTSQFEKRGVAINVPQWVPENCIQCNQCAFVCPHSAILPVLAKEEELVGAPANFTALEAKGKELKGYKFRIQINTLDCMGCGNCADICPPKEKALVMQPLDTQRDAQVPNLEYAARIPVKSEVLPRDSLKGSQFQEPLMEFSGACSGCGETPYVRVITQLFGERMFIANATGCSSIWGASAPSMPYKTNRLGQGPAWGNSLFEDAAEYGFGMNMSMFARRTHLADLAAKALESDASGDVKEALQGWLAGKNDPIKSKEYGDKLKKLLAGQKDGLLGQIAAMSDLYTKKSVWIFGGDGWAYDIGYGGLDHVLASGEDVNVFVMDTEVYSNTGGQSSKATPTGAVAKFAAAGKRTGKKDLARMVMTYGYVYVATVSMGYSKQQFLKVLKEAESFPGPSLVIAYATCINQGLRKGMGKSQDVMNTAVKSGYWPLFRYDPRLAAQGKNPFQLDSKAPDGSVEEFLMAQNRFAVLDRSFPEDAKRLRAQVAHELDVRFKELEHMAATNIFESFAPAGGKADGSVDFGEGAEFCTRDDTPMMARPDSGEACDQNRAGTSEQQGDLSKRTKK
What is the function of this protein?
Catalyzes the ferredoxin-dependent oxidative decarboxylation of pyruvate.  Required for the transfer of electrons from pyruvate to ferredoxin (PubMed:9294422, PubMed:7612653).  Ferredoxin I and ferredoxin II, which are single 4Fe-4S cluster ferredoxins are the most effective electron carriers of POR (PubMed:7612653).
What are the official names of this protein?
Pyruvate:ferredoxin oxidoreductase, PFOR, POR, Pyruvate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTP1_STYPL
Sequence: KGCVAIVMLTPLVEEGVNQCARYWPDEGSCTYHNFEIHLVSEHIWCEDYLVRSLYLKHLPSGETRTVTQFHFLSWPNDRVPSTAKPLLELRRKVTKCYKGHNSPVLV
What are the official names of this protein?
Tyrosine-protein phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family.
Protein: POT9_ARATH
Sequence: MAERVEASSVPEGENTIEEREVGAMWELEQKLDQPMDEEANKLNNMYREKGLSMLMLLRLSFQSLGIVYGDLGTSPLYVFYNTFPDGIDDSEDVIGALSLIIYSLLLIPLIKYVFIVCKANDNGQGGTLAIYSLLCRHAKVKLIPNQHRSDEDLTTYSRTVSAEGSFAAKTKKWLEGKEWRKRALLVVVLLGTCMMIGDGILTPAISVLSATGGIKVNNPKMSGDIVVLVAIVILIGLFSMQHYGTDKVGWLFAPIVLIWFLFIGATGMYNICKYDTSVLKAFSPTYIYLYFKRRGRDGWISLGGILLSITGTEALYADIAYFPLLAIQLAFTFFVFPCLLLAYCGQAAYLVIHKEHYQDAFYASIPDSVYWPMFIVATGAAIVGSQATISGTYSIVKQAVAHGCFPRVKIVHTSKKFLGQIYCPDINWILMLGCIAVTASFKKQSQIGNAYGTAVVLVMLVTTLLMVLIMLLVWHCHWILVLIFTFLSFFVELSYFSAVIFKIDEGGWVPLIIAAISLLVMSVWHYATVKKYEFEMHSKVSMSWILGLGPSLGLVRVPGIGLVYTELASGVPHIFSHFITNLPAIHSVVVFVCVKYLPVYTVPEEERFLVKRIGPKTFRMFRCVARYGYKDLHKKDDDFENKLLTKLSSFIRIETMMEPTSNSSTYSSTYSVNHTQDSTVDLIHNNNNHNHNNNMDMFSSMVDYTVSTLDTIVSAESLHNTVSFSQDNTVEEEETDELEFLKTCKESGVVHIMGNTVVKARTGSWLPKKIAIDYVYAFLAKICRANSVILHVPHETLLNVGQVFYV
What is the function of this protein?
Putative potassium transporter.
What are the official names of this protein?
Potassium transporter 9, AtPOT9.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FLHC_THASP
Sequence: MKNKSVIEEADDVRRAVEMVQLGARMQMLEVETRLSREKLLRIYKEVRGASPPKGMLPFSTDWFMTWQPNVHSSLFMNLYRYFTGPAGVHGLDAILKSYHLYLDHIETGVIEPALSLTRAWTLVRFFDADLLQMAACTRCGGEFVAHAHDPVHDYVCGLCNMPSRAGSARRKTTTRKAVAPTHKTTAASRKAVVA
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.