PharMolix/UniProtQA huggingface dataset:
Protein: RSGA_LIMRJ
Sequence: MKTGIIQQSLSGFYDVIADEKIYRTRARGNFRQRKIKPVVGDHVEFSAENQQEGYLLKILPRRNQLVRPPVANVDMAVVVTSAKEPAFSANLLDRQLIALEAQDVTPLIYFSKTDLLTDDEYQQLLPTIEGYRKIGYQVYAAREPFDSDQLANLMEGLKGNIVTMMGQTGAGKSTLLNHLAPQLKLATGEISQALQRGRHTTRKVSLLDVNGALIADTPGFSSYETFDMTVNDLPQLFPEMAKISADCKFRGCLHIKEPQCAVKEAVNNGIIMKSRYNDYLQFHELIANQKPNYKK
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VDTR1_BYSSP
Sequence: MSWQGHEGPKVKLRSACDRCSANKVKCTQEKPECERCRLLSLPCNYSRSMRIGKPPKSRQRGLSNIDPKTLMGGTVTKKLRPCPSAPESACRGSFEDGDGGPWTETMTFEEMLSRPSPPPFAGPSHNSNRPTNMASTNQDQYYHDKGKHGETMDEMLQTLVPDSVQFIEFPNTAREDQKQHPELRSEEEYSDYRSKSLFEEGLARIAPDCAGGIMDVLYGEEALVQMPNLPSSTHEGSSNTHVTSSHNCTRAVMENLAKLYQVCAPAGVENGSHPTTDQVLKANSDAMKDAADLLACPCAKDFCFPIILGITACRVLAWYQVVIDMYDPEIPMATMPTAREDIKHCPIAFGAYQLDEEVSQAMTSQFVLRNLRAMTRFVKTYVENFCSDINKNRPGSCSLIYRSLGTFMQTRLGNTIEQLEDRLAAFDGEYTKNIG
What is the function of this protein?
Transcription factor that regulates expression of the viriditoxin biosynthesis cluster and viriditoxin synthesis.
What are the official names of this protein?
Transcriptionnal regulator VdtR, Viriditoxin biosynthesis cluster protein R.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3751_VIBCH
Sequence: MIVTTTPNIEGKRIVRYCGVIAGEAILGANIFKDLSAGIRDIVGGRSGTYERELEKARAIALEELQQHAVALGANAVVGIDLDYETFGKANGMLMVSVSGTAVVVE
What are the official names of this protein?
UPF0145 protein VC_A0951.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RL10_METST
Sequence: MHHVADWKKEKVAELEDLTNSHEIIGIVNLADIPAKQLQTMRKSLGDNAILKMSRKNFIKIALENSDKEEVEGLADYLEGQPAMVFTKMNPFKLFKILEDSKTEAPAKAGSIAPADIVVPAGDTSFPPGPILGELQQVGIPAKIDKGSIVVTDDAKIVDEGEEIPKAVADILTKLEIHPMEVGIDLLAVCEGDTIYTADVLAIDEEETIQTLANAYQSAINLSVYAGILNSESAPLLIQKAARDALNLAINANILTSETTDKILSKAYAQMLAVAKLLSSEAIDDELNEKLNSQAAAAPVAVEDNTEEPEEEEEEEEDAAESAAAGLGALFG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: ALR_LEPIN
Sequence: MQDINSGSSSMKDTYSSWIEISKRSLSNNLDNFRSILRPNSTLTAILKSNAYGHGIEPMTRLCIEAGISRIGVNSIEEALLIRNIDSKIPILIMGEIQNPEKRKDVLSDPNFWIVFSRPETARILSSFLPAPKLHLKIDTGMGRLGSHGETLKQTLSELKNVGITLGGICTHFASTEDVLEHKYSLMQTQKFEEAIFLAKSFGYNHLIRHACASASTMLFPNAHFDMVRIGISLYGLWPSIQTRLSLNLTGNKNFQLNPILSWKSRIVHIQYHPADSYIGYGSTFQTSYPTKVAIVPVGYYEGLDRKLSSNGDMLVLGKKARIIGRICMNMTMLDVTHIPGAEVGSIVTIIGQDGEESITADDLADRTHTINYEVMTRISESIPRIVVD
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: LPTE_PECAS
Sequence: MRHRLFTLVLGLAVLITAGCGFHLRGTTQVPAQLQTLVLDSSDPYGPLTRAVREQLRLSDVKIVDDATRQDIPSLRVLSSSETRDTVSIFQDGKTAEYQMVLTLQAQVLMPGEDIYPLSVTVFRTFFDNPLAALAKDAEQDIVRQEMREQAAQQLVRKLLTINGSQEVKNRLQSTDSPTAAKRS
What is the function of this protein?
Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.  Required for the proper assembly of LptD.  Binds LPS and may serve as the LPS recognition site at the outer membrane.
What are the official names of this protein?
LPS-assembly lipoprotein LptE.
What is the protein family that this protein belongs to?
Belongs to the LptE lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: NUOI2_GEOMG
Sequence: MIMPLINGLKITLKHMFMKPVTLQYPDERPTPSPNFRGLHALKVSHSKAKCVCCYLCPTVCPAKCITVEAGEDQEHNKYAERYEIDMLRCIFCGYCVEACPVDALKMTGEFELANYKREDFVFVKERLLEK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I 2, NADH dehydrogenase I subunit I 2, NDH-1 subunit I 2.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HIS8_GLUDA
Sequence: MSRFWSPVVHRLTPYVPGEQPKLTNLIKLNTNESPYGPPPGALEAIRAAADDTLRLYSDPTSERLRAAIAQAHDVGMDEIFVGNGSDEVLAHAFHALLQHDAPLLTPDITYSFYPVYCGLYGIAHQPVPLDDAMRIDVDDYRRPCAGLVLPNPNAPTGIALGLGQIETLLRAQPDRVVVIDEAYVDFGADTAIPLVRRFPNLLVVRTLSKSHALAGLRVGYAIGHPDLVEALNRVKDSFNSYPLDRLAQAGAAAAIADREWLARTTGKIIKTRIGLTSSLRGLGFEVLPSQANFVFARHPDRDAAHLAAALRERAIIVRHFRTPRIAEWLRITVGTDEECRVLTDALGTILTRNAD
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: URK_STRPN
Sequence: MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKDQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK
What are the official names of this protein?
Uridine kinase, Cytidine monophosphokinase, Uridine monophosphokinase.
What is the protein family that this protein belongs to?
Belongs to the uridine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDTG_ECOLI
Sequence: MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQVSN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IMSP1_RUDPH
Sequence: RQAARVCSTRFQPENWNIDPIQRRNNCYNYATNIQTNTFAQPGRASGRRYRENVGGEVYSACLRDGLTGLRAPDAGTECLIALVVWPGEDYHFYRLDNNGYWSHKSGRTEARNTDDSGDPIIDPRTADRGPYSDFVGWLGVGPRARVN
What are the official names of this protein?
Insoluble matrix shell protein 1, IMSP1.
What are the subcellular locations of this protein?
Secreted.
Protein: WTF9_SCHPM
Sequence: MKNKYYPLRSSMDEMSAKNDNEIDLEKGPLPEYNSEDGSTLPPYSDLNNPKQMGQNITKLFNWNKSTTPPDYDENRLPITDEGNNPPNTHRENHSSGTTDNSSPFLIKLLISFTSIILFNAPAVCYLKYKDAFFKNYGAAEWTLFGFWCLVCTLALLFLTYFYETWSKAVKVTIIFLAQCIKVTAVFLAQCVKVTAISLAKCVKVTAVGLYNSREKWVVIIWLLWVVICYTLFLRSKFGNLNLNKALICSTCSISAALLLFLLYVRLPFWTLKHMFSGLFQVLGVQSCVVIVTKGLMHLFDKHIDATGYEIEVSSLFVIGNFLFFYEMECPGALRRMPKSIRNGIASFLEGTGRAIRGANDNNNSIPLEETEAESEV
What is the function of this protein?
Forms toxic aggregates that disrupt spore maturation.
What are the official names of this protein?
Meiotic driver cw9.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
[Isoform 1]: Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Note=Contained within spores expressing the isoform and localizes isoform 2 to the vacuole. SUBCELLULAR LOCATION: [Isoform 2]: Ascus epiplasm. Cytoplasm. Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Localizes in trans to all spores within an ascus. Localization to the spore vacuole is dependent on isoform 1.
Protein: CD69_HUMAN
Sequence: MSSENCFVAENSSLHPESGQENDATSPHFSTRHEGSFQVPVLCAVMNVVFITILIIALIALSVGQYNCPGQYTFSMPSDSHVSSCSEDWVGYQRKCYFISTVKRSWTSAQNACSEHGATLAVIDSEKDMNFLKRYAGREEHWVGLKKEPGHPWKWSNGKEFNNWFNVTGSDKCVFLKNTEVSSMECEKNLYWICNKPYK
What is the function of this protein?
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
What are the official names of this protein?
Early activation antigen CD69, Activation inducer molecule, AIM, BL-AC/P26, C-type lectin domain family 2 member C, EA1, Early T-cell activation antigen p60, GP32/28, Leukocyte surface antigen Leu-23, MLR-3.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RL13_DESHD
Sequence: MSTFFAKANAVERKWYVIDAAGLPLGRLATEAARILRGKHKPTFTPNVDTGDHVIIINAEKVVLTGNKLDQKMYRRHSGYPGGLKETPYRKLMQNMPERAVEHAVKGMLPHNKLGAQMYTKLKVYRDENHPHQAQQPEVWTIQ
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GLYCO_BEFVB
Sequence: MFKVLIITLLVNKIHLEKIYNVPVNCGELHPVKAHEIKCPQRLNELSLQAHHNLAKDEHYNKICRPQLKDDAHLEGFICRKQRWITKCSETWYFSTSIEYQILEVIPEYSGCTDAVKKLDQGALIPPYYPPAGCFWNTEMNQEIEFYVLIQHKPFLNPYDNLIYDSRFLTPCTINDSKTKGCPLKDITGTWIPDVRVEEISEHCNNKHWECITVKSFRSELNDKERLWEAPDIGLVHVNKGCLSTFCGKNGIIFEDGEWWSIENQTESDFQNFKIEKCKGKKPGFRMHTDRTEFEELDIKAELEHERCLNTISKILNKENINTLDMSYLAPTRPGRDYAYLFEQTSWQEKLCLSLPDSGRVSKDCNIDWRTSTRGGMVKKNHYGIGSYKRAWCEYRPFVDKNEDGYIDIQELNGHNMSGNHAILETAPAGGSSGNRLNVTLNGMIFVEPTKLYLHTKSLYEGIEDYQKLIKFEVMEYDNVEENLIRYEEDEKFKPVNLNPHEKSQINRTDIVREIQKGGKKVLSAVVGWFTSTAKAVRWTIWAVGAIVTTYAIYKLYKMVKSNSSHSKHREADLEGLQSTTKENMRVEKNDKNYQDLELGLYEEIRSIKGGSKQTGDDRFFDH
What is the function of this protein?
Attaches the virus to host cellular receptors, inducing endocytosis of the virion.  The acidic pH of the endosome induces conformational changes in the glycoprotein trimer which trigger fusion between the virus and the cell membrane (By similarity).
What are the official names of this protein?
Glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the rhabdoviruses glycoprotein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein.
Protein: ACTZ_DROME
Sequence: MEPYDVVVNQPVVIDNGSGVIKAGFAGEHIPKCRFPNYIGRPKHVRVMAGALEGDIFVGPKAEEHRGLLSIRYPMEHGIVTDWNDMERIWSYIYSKEQLATFTEDHPVLLTEAPLNPRRNREKAAEFFFEGINAPALFVSMQAVLSLYATGRVTGVVLDSGDGVTHAVPIYEGFAMPHSIMRVDIAGRDVTRYLKTLIRREGFNFRSTAEFEIVRSIKEKVCYLATNPQKEETVETEKFAYKLPDGKIFEIGPARFRAPEVLFRPDLLGEECEGIHDVLMYSIEKSDMDLRKMLYQNIVLSGGSTLFKGFGDRLLSELKKHSAKDLKIRIAAPQERLYSTWMGGSILASLDTFKKMWISKREYEEEGQKAVHRKTF
What are the official names of this protein?
Actin-related protein 1, Actin-like protein 1, Actin-like protein 87C.
What is the protein family that this protein belongs to?
Belongs to the actin family. ARP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LMTK1_MOUSE
Sequence: MSSSFFNPSFAFSSHFDPDGAPLSELSWSSSLAVVAVSFSGIFTVVILMLACLCCKKGGIGFKEFENAEGDEYVADFSEQGSPAAAAQTGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDLGRHSLLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLLVVDQTKSSNVWSLGVTIWELFELGAQPYPQHSDRQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGTTELEEEFERRWRSLRPGGSTGLGSGSAAPAAATAASAELTAASSFPLLERFTSDGFHVDSDDVLTVTETSHGLNFEYKWEAGCGAEEYPPSGAASSPGSAARLQELCAPDSSPPGVVPVLSAHSPSVGSEYFIRLEGAVPAAGHDPDCAGCAPSPQAVTDQDNNSEESTVASLAMEPLLGHAPPTEGLWGPCDHHSHRRQGSPCPSRSPSPGTPMLPAEDIDWGVATFCPPFFDDPLGASPSGSPGAQPSPSDEEPEEGKVGLAAQCGHWSSNMSANNNSASRDPESWDPGYVSSFTDSYRDDCSSLEQTPRASPEVGHLLSQEDPRDFLPGLVAVSPGQEPSRPFNLLPLCPAKGLAPAACLITSPWTEGAVGGAENPIVEPKLAQEAEGSAEPQLPLPSVPSPSCEGASLPSEEASAPDILPASPTPAAGSWVTVPEPAPTLESSGSSLGQEAPSSEDEDTTEATSGVFTDLSSDGPHTEKSGIVPALRSLQKQVGTPDSLDSLDIPSSASDGGCEVLSPSAAGPPGGQPRAVDSGYDTENYESPEFVLKEAHESSEPEAFGEPASEGESPGPDPLLSVSLGGLSKKSPYRDSAYFSDLDAESEPTFGPEKHSGIQDSQKEQDLRSPPSPGHQSVQAFPRSAVSSEVLSPPQQSEEPLPEVPRPEPLGAQGPVGVQPVPGPSHSKCFPLTSVPLISEGSGTEPQGPSGQLSGRAQQGQMGNPSTPRSPLCLALPGHPGALEGRPEEDEDTEDSEESDEELRCYSVQEPSEDSEEEPPAVPVVVAESQSARNLRSLLKMPSLLSEAFCDDLERKKKAVSFFDDVTVYLFDQESPTRETGEPFPSTKESLPTFLEGGPSSPSATGLPLRAGHSPDSSAPEPGSRFEWDGDFPLVPGKAALVTELDPADPVLAAPPTPAAPFSRFTVSPTPASRFSITHISDSDAQSVGGPAAGAGGRYTEA
What is the function of this protein?
May be involved in neuronal differentiation.
What are the official names of this protein?
Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, Lemur tyrosine kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single- pass type I membrane protein. Cytoplasm. Cytoplasm, perinuclear region. Cell projection, dendrite. Cell projection, axon. Cell projection, growth cone. Note=Predominantly perinuclear. SUBCELLULAR LOCATION: [Isoform 2]: Membrane. Note=Peripheral membrane protein. SUBCELLULAR LOCATION: [Isoform 3]: Membrane; Single-pass type I membrane protein.
Protein: RL27_BURP0
Sequence: MAHKKAGGSSRNGRDSESKRLGVKVYGGQAINAGGIIVRQRGTRMHAGENVGMGKDHTLFALVDGHVKFTTKGAAKKHTVVVVPAAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: DPOLA_ARATH
Sequence: MSGDNSTETGRRRSRGAEASSRKDTLERLKAIRQGGIRSASGGGYDIRLQKPIFDTVDDEEYDALVSRRREEARGFVVEDGEGGDLGYLDEGEEEDWSKPSGPESTDESDDGGRFSGRLKKKKKGKEQTQQPQVKKVNPALKAAATITGEGRLSSMFTSSSFKKVKETDKAQYEGILDEIIAQVTPDESDRKKHTRRKLPGTVPVTIFKNKKLFSVASSMGMKESEPTPSTYEGDSVSMDNELMKEEDMKESEVIPSETMELLGSDIVKEDGSNKIRKTEVKSELGVKEVFTLNATIDMKEKDSALSATAGWKEAMGKVGTENGALLGSSSEGKTEFDLDADGSLRFFILDAYEEAFGASMGTIYLFGKVKMGDTYKSCCVVVKNIQRCVYAIPNDSIFPSHELIMLEQEVKDSRLSPESFRGKLHEMASKLKNEIAQELLQLNVSNFSMAPVKRNYAFERPDVPAGEQYVLKINYSFKDRPLPEDLKGESFSALLGSHTSALEHFILKRKIMGPCWLKISSFSTCSPSEGVSWCKFEVTVQSPKDITILVSEEKVVHPPAVVTAINLKTIVNEKQNISEIVSASVLCFHNAKIDVPMPAPERKRSGILSHFTVVRNPEGTGYPIGWKKEVSDRNSKNGCNVLSIENSERALLNRLFLELNKLDSDILVGHNISGFDLDVLLQRAQACKVQSSMWSKIGRLKRSFMPKLKGNSNYGSGATPGLMSCIAGRLLCDTDLCSRDLLKEVSYSLTDLSKTQLNRDRKEIAPNDIPKMFQSSKTLVELIECGETDAWLSMELMFHLSVLPLTLQLTNISGNLWGKTLQGARAQRIEYYLLHTFHSKKFILPDKISQRMKEIKSSKRRMDYAPEDRNVDELDADLTLENDPSKGSKTKKGPAYAGGLVLEPKRGLYDKYVLLLDFNSLYPSIIQEYNICFTTIPRSEDGVPRLPSSQTPGILPKLMEHLVSIRKSVKLKMKKETGLKYWELDIRQQALKLTANSMYGCLGFSNSRFYAKPLAELITLQGRDILQRTVDLVQNHLNLEVIYGDTDSIMIHSGLDDIEEVKAIKSKVIQEVNKKYRCLKIDCDGIYKRMLLLRKKKYAAVKLQFKDGKPCEDIERKGVDMVRRDWSLLSKEIGDLCLSKILYGGSCEDVVEAIHNELMKIKEEMRNGQVALEKYVITKTLTKPPAAYPDSKSQPHVQVALRMRQRGYKEGFNAKDTVPYIICYEQGNASSASSAGIAERARHPDEVKSEGSRWLVDIDYYLAQQIHPVVSRLCAEIQGTSPERLAECLGLDPSKYRSKSNDATSSDPSTSLLFATSDEERYKSCEPLALTCPSCSTAFNCPSIISSVCASISKKPATPETEESDSTFWLKLHCPKCQQEDSTGIISPAMIANQVKRQIDGFVSMYYKGIMVCEDESCKHTTRSPNFRLLGERERGTVCPNYPNCNGTLLRKYTEADLYKQLSYFCHILDTQCSLEKMDVGVRIQVEKAMTKIRPAVKSAAAITRSSRDRCAYGWMQLTDIVI
What is the function of this protein?
Polymerase alpha in a complex with DNA primase is a replicative polymerase.
What are the official names of this protein?
DNA polymerase alpha catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVA_CARHZ
Sequence: MIAVLKGKVLDKTLDSVVVDVNGIGFKVAVLPRELGSLNLNSEVVMYTSLQVREDGWFLYGFSDEETRKFFDLLLSVSGIGPKAALAILNEFTPEKLNWVIANKDEKALTKVPGVGKKNAQRLFLELKDKIGYTSFTSNEESVENFQDLWGDVYKGLLSLGLSAAEAREILGKIDKKSVKTPEEGIALALRFLNK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: MURE_JANMA
Sequence: MSILTTTALASILDWLAANAPKAELASDSRRIAQGDVFVAYPGDEADGRSYIANAIERGAQAVIYEAAGCTWDAEWDVAHLAIDDLKEHAGEIAAAYYAHPDRSMFTVAITGTNGKTSCAQWLGSALSRLGQPTAVIGTLGVGIFTNGGHGSFDVTGYTTPDAVLLQRSLVNVSNLGATALAIEASSIGLHQGRLSGMHFDMALFTNFTRDHLDYHGDMAAYEEAKAMLFDWPGLQHAVINLDDAMGVRLVQRLQSRQADVGITGYTLSDKKIDGIAVLRATDIRSNQSGTVFQLESSAGNTQVKTQLVGQFNVSNVLGIIGILLAKGIALQDAVNAVEALTAVPGRMQQLGGGEAPLVVIDYAHTPDALEKTLATLRSVANDRGGELWCVFGCGGDRDPGKRPQMGKVSMAADHIVVTTDNPRNEEPANIIGDIVAGITAPKNAPQIIEDRASAILWAGRHAARQDVILLAGKGHEAYQEVKGRKLPFLDADHAALALSTRVMQGAS
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXO_DROVI
Sequence: MDGFAQDWPNLPRSDNGLHMDQLVGELPTDGGFEPQTRARSNTWPCPRPENFVEPVDELDSTKASNQQLASGDPQQAMQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVSYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQGGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGFQLSPDFRQRASSNASSCGRLSPIRALDLEPDWGFSVDYQNTTMTQAQAQQLDQLAGSMAEELKLQSDMLQQQGFSAASGLPTQPPPPYQPPQQPQLPQGYSLNGPGYAAMQPQPQPQGQGQCLLHRSLNCGCLHSAPVRDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVLLDGSADNAALLVQHQQQQQQQQQQQRQQLSSGLEGQCLEALNSEQIDEFNLEDFQGGLECNVEELLQQEMRYDGLLDINIPLAAVNTNTNNVILTNNSTNSGSSNAASNSSAGVQLNQLQAQLQLQQQQQQQQQQQQHQQQLLMSNNNNNNNNNNNSNNSLELATQTATANLNARVQYSQPSVVTSPPSWVH
What is the function of this protein?
Transcription factor involved in the regulation of the insulin signaling pathway.  Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR.  Involved in negative regulation of the cell cycle, modulating cell growth and proliferation.  In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.  Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging.  Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis (By similarity).
What are the official names of this protein?
Forkhead box protein O.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation (By similarity).
Protein: RARR2_CRIGR
Sequence: MKYLLISLALWLGMVGIHGTELELSETQRRGLQVALEEFHKHPPVQWAFQEIGVDNANDMVFSAGTFVRLEFKLQQTSCFKKDWKNPECKIKANGRKRKCLACIKLDPRGKVLGRMVHCPILKQGLQQELQESQCNRITQAGEDPRSHFFPGQFAFSRALKHK
What is the function of this protein?
Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1).  Acts also as a ligand for CMKLR2.  Can also bind to C-C chemokine receptor-like 2 (CCRL2), but with a lower affinity than it does to CMKLR1 or CMKLR2.  Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue.  Also acts as a pro-inflammatory adipokine, causing an increase in secretion of pro-inflammatory and prodiabetic adipokines, which further impair adipose tissue metabolic function and have negative systemic effects including impaired insulin sensitivity, altered glucose and lipid metabolism, and a decrease in vascular function in other tissues.  Can have both pro- and anti-inflammatory properties depending on the modality of enzymatic cleavage by different classes of proteases.  Acts as a chemotactic factor for leukocyte populations expressing CMKLR1, particularly immature plasmacytoid dendritic cells, but also immature myeloid DCs, macrophages and natural killer cells.  Exerts an anti-inflammatory role by preventing TNF/TNFA-induced VCAM1 expression and monocytes adhesion in vascular endothelial cells.  The effect is mediated via inhibiting activation of NF-kappa-B and CRK/p38 through stimulation of AKT1/NOS3 signaling and nitric oxide production.  Its dual role in inflammation and metabolism might provide a link Exhibits an antimicrobial function in the skin (By similarity).
What are the official names of this protein?
Retinoic acid receptor responder protein 2, Chemerin, RAR-responsive protein TIG2, Tazarotene-induced gene 2 protein.
What are the subcellular locations of this protein?
Secreted.
Protein: SODF2_ORYSJ
Sequence: MAAFASALRVLPSPPAAVPRRLRSREQRQGCRSRRYSKVVAYYALTTPPYKLDALEPYISKRTVELHWGKHQQDYVDSLNKQLATSMFYGYTLEELIKEAYNNGNPLPEYNNAAQVWNHHFFWESMQPEGGGSPGRGVLQQIEKDFGSFTNFREEFIRSALSLLGSGWVWLVLKRKERKFSVVHTQNAISPLALGDIPLINLDLWEHAYYLDYKDDRRMYVTNFIDHLVSWDTVTLRMMRAEAFVNLGEPNIPVA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Fe] 2, chloroplastic, Iron-superoxide dismutase.
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: JZT51_CHIGU
Sequence: MTRKILAVLLVFTLVACNNAEKYSETDVEDSPMIQERRCEPSGKPCRPLMRIPCCGSCVRGKCA
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U6-theraphotoxin-Cg1a, U6-TRTX-Cg1a, Jingzhaotoxin F7-8.06, Jingzhaotoxin-51, JZTX-51, Peptide F7-8.06.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 36 family. 02 subfamily.
What are the subcellular locations of this protein?
Secreted.