PharMolix/UniProtQA huggingface dataset:
Protein: PIGW_DICDI
Sequence: MDDQYKNDHQNFVSGNDGSTFFETCFILTLMPISVLFQRVVFATFFNNDKFPLPLALRFILEFFFIIVPFISAITFTELTPFLIVGMLITCLVVPMFAQKNVTIYFKNPKETLLNLNSMRKGFLEEYRAFVMAATCICILAVDFQVFPRRLGKTETYGISLMDIGVGSVVLSGALVSRQSRSSLIEKQQKKKREEEEDDNDKINKTSSSSSSSSSALKQQQQQVLSRSSLMWHQVKAQAPLMILGFVRMILTKSINYQEHVSEYGLHWNFFFTLGFVSISLAFLKFNANISAILGVVLICVYQFLLNSFGLTDYILNHPRDNLISMNKEGICSFVGYLAIYLIGTKIGTELFKVRSSLTEWRKFATKLLISSIVFYILWILCEIYIDKTSRRMANLGYVLAILSINLFNFSINILITLITGNHNASVIAKSINRNQLFIFLLGNILTGLINFSMKTIYAPVEQSMIIITSYTFALCLLAFILDYKNINIKFW
What is the function of this protein?
Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
What are the official names of this protein?
Phosphatidylinositol-glycan biosynthesis class W protein.
What is the protein family that this protein belongs to?
Belongs to the PIGW family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HUTH_BACCN
Sequence: MVTLTGHSLTVEEMKRLLFEREGVTACPDSMQKVAECREAVEKIVEDGKVVYGITTGFGKFSDVLIQKEDVKELQHNLIQSHACGVGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLELVNRNIHPVIPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGKRVHAMIALTEEGLEPIELEAKEGLALINGTQAMTAQGILSYIEAETLAYQSELIASMTLEGLRGIIDAFDENVHKARGYKEQIEVAQRIRNILQDSKLVTKQGELRVQDAYSLRCIPQVHGASWQVLHYVKEKLEIEMNAATDNPLIFDGGEKVISGGNFHGQPIAFAMDFLKVGMAEIANISERRIERLVNPQLNDLPPFLSPKPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHAHQIIQNVRRVLAIEMICAMQAAEYRGIEEMSSATKIFYHQGRQQVPSITNDRIFSTDIENIAHWLKTSPFTLERLNVNATL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EXO5_KLULA
Sequence: MIRRFLRLYSIKRNTHLILEDLQSIKFNKDDLKAIDSALKLVTVKQTTSSSKLSRTRAKQEYIDRKLEVIRNIFPGEPDSEYVSMEPPNDLKNPYFDVYSKTVLDEDGNIKFAGTERLSVTKLLTKRWCELNQMYDIYSRLPIFEHRQLKVGKVEHEKLEKAIHGVAPAVEDFMETYEWELAEDDTHQLADNWFQCIHRLLTLFSSGEAREILCHGYIDSRSCQLIEGQVKDDRDILISGIIDHVVLFHVNNNKPKSLEPALREKNGFDLLKIISFLGDTIPQAEDLKIAVGDVKTRPRAIVPNHASVVRASKLQVMYYRFFLENLGKDPEIAYQKLILNATRRDINIDTPINISNLIYFMEIDPAIRPDLERIMLGEPIGFEPFDRYYQSELENGDEDNIAMPSEIGEANEYNLSQYADLTMEESTLEKYGTFYQKWANPPTLRYFAARLAQLYGTLLPLLSNDLMIEYYTGDYKFYTDKFQYDSALLKQECHSSSQFWFGKRSVEPIVPTKKNLVTFCKYCDFHDVCGWRANGNKMFKQLGPTLEEISKL
What is the function of this protein?
Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination.  Releases dinucleotides as main products of catalysis.  Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity).
What are the official names of this protein?
Exonuclease V, mitochondrial, Exo V, Defects in morphology protein 1.
What is the protein family that this protein belongs to?
Belongs to the EXO5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FOXM1_HUMAN
Sequence: MKTSPRRPLILKRRRLPLPVQNAPSETSEEEPKRSPAQQESNQAEASKEVAESNSCKFPAGIKIINHPTMPNTQVVAIPNNANIHSIITALTAKGKESGSSGPNKFILISCGGAPTQPPGLRPQTQTSYDAKRTEVTLETLGPKPAARDVNLPRPPGALCEQKRETCADGEAAGCTINNSLSNIQWLRKMSSDGLGSRSIKQEMEEKENCHLEQRQVKVEEPSRPSASWQNSVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGWKNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLDQVFKPLDPGSPQLPEHLESQQKRPNPELRRNMTIKTELPLGARRKMKPLLPRVSSYLVPIQFPVNQSLVLQPSVKVPLPLAASLMSSELARHSKRVRIAPKVLLAEEGIAPLSSAGPGKEEKLLFGEGFSPLLPVQTIKEEEIQPGEEMPHLARPIKVESPPLEEWPSPAPSFKEESSHSWEDSSQSPTPRPKKSYSGLRSPTRCVSEMLVIQHRERRERSRSRRKQHLLPPCVDEPELLFSEGPSTSRWAAELPFPADSSDPASQLSYSQEVGGPFKTPIKETLPISSTPSKSVLPRTPESWRLTPPAKVGGLDFSPVQTSQGASDPLPDPLGLMDLSTTPLQSAPPLESPQRLLSSEPLDLISVPFGNSSPSDIDVPKPGSPEPQVSGLAANRSLTEGLVLDTMNDSLSKILLDISFPGLDEDPLGPDNINWSQFIPELQ
What is the function of this protein?
Transcription factor regulating the expression of cell cycle genes essential for DNA replication and mitosis (PubMed:19160488, PubMed:20360045).  Plays a role in the control of cell proliferation (PubMed:19160488).  Also plays a role in DNA break repair, participating in the DNA damage checkpoint response (PubMed:17101782).  Promotes transcription of PHB2 (PubMed:33754036).
What are the official names of this protein?
Forkhead box protein M1, Forkhead-related protein FKHL16, Hepatocyte nuclear factor 3 forkhead homolog 11, HFH-11, HNF-3/fork-head homolog 11, M-phase phosphoprotein 2, MPM-2 reactive phosphoprotein 2, Transcription factor Trident, Winged-helix factor from INS-1 cells.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL16_STAA8
Sequence: MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: TAIL_BPMR2
Sequence: MANMKNSNDRIILFRKAGEKVDATKMLFLTEYGLSHEADTDTEDTMDGSYNTGGSVESTMSGTAKMFYGDDFADEIEDAVVDRVLYEAWEVESRIPGKNGDATKFKAKYFQGFHNKFELKAEANGIDEYEYEYGVNGRFQRGFATLPEAVTKKLKATGYRFHDTTKADALTGEDLTAIPQPKVDSSTVTPGEV
What are the official names of this protein?
Putative tail protein, Putative major tail protein.
What are the subcellular locations of this protein?
Virion.
Protein: GLSA_SACEN
Sequence: MEMSSLLERITDQIAPLRGSGEVADYIPALARADPDRFGIAVAEVDGGVHGAGDWEAPFSMQSISKVFTLAMVLAEGDDTLWRRVGREPSGNPFNSLVQLEHERGIPRNPFINAGALAVTDQLISLTGDAVGNLLEFLRTESANPALPIDDEVAISERAHADRNLALAHFMASYGNMRNPVDDVIDQYVRQCSIAMSCHDLAEAGLLLARHGVRRDGSGYLSRSQAKRINAIMLTCGTYDAAGEFAYHVGIPGKSGVGGGILAIVPGRCAVAVWSPGLDRRGNSVAGVAALDHFTTLTGWSVF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: RSMH_SHEVD
Sequence: MSQEFSHLSVLLTETVAGLNIKPDGIYIDGTFGRGGHSREVLKHLGDNGRLIAIDRDPQAIIAAEQFADDARFSIVHGGFGQLADYVEDLGLKGKVDGVLLDFGVSSPQLDDAERGFSFLRDGPLDMRMDNSQGQTAAEWIARTEIEDMAWVFKTYGEEKNSRHIARCIAADRDKTPFLRTKELADLIARICKSKERNKHPATRVFQAIRIYINSELEQIDQALEGALKVLAPQGRLSVISFHSLEDRIVKRFIRRHSQGMSVPHGLPITEAEINKTRLLKAVGKATKPSTEEVEMNKRSRSSVLRVAERLEY
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_MAGMM
Sequence: MKVYYDSDADLGLIQSKKVAIIGYGSQGHAHALNLKDSGVDVVVGLRAGSSSWMKAEGSGLQVAEVADAVGGADLVMMLVPDEHQAKIYREQIAPNLKDDAALVFAHGFNIHYGQIEAPAGVDVFLVAPKGPGHLVRAEYLRGGGVPSLVAIHQNATGKALDLALSYASANGGGRAGIIETSFKEETETDLFGEQAVLCGGITALIQAGFETLVEAGYAPEMAYFECLHETKLIVDLIYEGGIANMRYSISNTAEYGDLTRGPRVITEETKKEMKKILDEIQTGEFPREWISENISGRPKFLGLRRRGEAHQIEQVGAKLRAMMPWIQASKLVDKAKN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: GPR35_HUMAN
Sequence: MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
What is the function of this protein?
Acts as a receptor for kynurenic acid, an intermediate in the tryptophan metabolic pathway.  The activity of this receptor is mediated by G-proteins that elicit calcium mobilization and inositol phosphate production through G(qi/o) proteins.
What are the official names of this protein?
G-protein coupled receptor 35, Kynurenic acid receptor, KYNA receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Internalized to the cytoplasm after exposure to kynurenic acid.
Protein: PURT_SHESW
Sequence: MIGTPYTEGARRAMLLGCGELGKEVAIELQRLGVEVIGVDRYANAPAMQVAHRSHVINMLDAKALRAIIELEKPHLVIPEIEAIATQTLVEMEAEGVNIIPTARATKLTMDREGIRRLAAETLGLPTSPYFFCDTETEFNQAIREIGVPCVVKPVMSSSGKGQSVIRDIAQSNKAWQYAQEGGRAGGGRVIVEGFVPFDYEITLLTVSAVNGIHFCAPIGHRQEDGDYRESWQPQAMSDEVLAKSQAIASKVVEALGGYGLFGVELFVKGNEVYFSEVSPRPHDTGLVTLISQDLSEFALHVRAILGLPIPNIHQHGPSASAVILAEGTSSNIRYQGIGAALEAVNTQLRLFAKPDIDGRRRLGVALARDIDIDSAISKALDSASKVKVIF
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: RIBB_PASMU
Sequence: MNQSILSPFGQSEERAIAAINAFKQGNGVLVLDDEDRENEGDLIFPAETITVEQMTMLIRYGSGIVCLCLSDEICQQLDLPPMVTENTSVNKTAFTVTIEAAKGVSTGVSATDRVTTIRAAVADNAKPSDLSRPGHIFPLRAMTGGVLKRRGHTEASVDLARLAGYKAAGVICEITNDDGSMARAPEIVTFAQKFGFPVVTIEDLVAYRQKYDV
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: SST_XANOM
Sequence: MTEFIPLGTLYHALPSPFQMKRGGVLHQAHVAYETWGALAADRSNAVLIVTGLSPNAHAAANQANPEPGWWEAMVGPGKPIDTARWFVVCVNSLGSCKGSTGPASVNPATGALYRLTFPDLSIEDVADAAADVVRALGIAQLACLIGNSMGGMTALALLLRHPGIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWNGGHYDDTRYPESGMRMARKLGVITYRSALEWDGRFGRVRLDSEQSEDDPFGLEFQVESYLEGHARRFVRFFDPNCYLYLSRSMDWFDLAEYVDDKPAADMGIDSPGADALPAAKSETGVSTASTVLAGLARIRIARALAIGANTDILFPVQQQEQIADGLRAGDADARFIGLDSPQGHDAFLVDFARFGPAVRDFLQGC
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine.
What are the official names of this protein?
Serine O-succinyltransferase, SST.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF_CWPXG
Sequence: MAEWHKIIEDISKNNKFEDAAIVDYKTTKNVLAAIPNRTFAKINPGEVIPLITNHNILKPLIGQKFCIVYTNSLMDENTYAMELLTGYAPVSPIVIARTHTALIFLMGKPTTSRRDVYRTCRDHATRVRATGN
What is the function of this protein?
More likely to influence phosphoinositide metabolism than actin assembly.
What are the official names of this protein?
Profilin.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
Protein: NODC_HYPPI
Sequence: MSLGLQCLAAVLFSALFSLGVILVHLPWRALKSKDPRERILGSPKELVPTCPYEYIRNIYGRHHWAPFVAKLAPNLKESDSDRYTMVLEIMDCIHLCLIMVDDITDDSDYRKGRPAAHIIYGRSETANRAYLRVSQIINKTTQDFPRLAPWVTQSLAEILEGQDISLVWRRDGLTSFPKAHDERVIAYRCMSSLKTGALFRLLGRLVLENRSMDDTLSQVGYYSQLQNDCKNVFSSEYAKAKGTLAEDLRNRELTYPIILALNEPEGFYIEKAFESGSPRDIQNAIGVIQSENVYRACLDELKQYESNVREWVTLWGRKEKLDLTH
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the indole diterpenes nodulisporic acids (NA).  Nodulisporic acid A (NAA) and its chemically modified derivatives are of particular significance because of their highly potent insecticidal activity against blood-feeding arthropods and lack of observable adverse effects on mammals, in particular the tremogenicity associated with the paspaline-derived IDTs is not observed (PubMed:29283570).  The geranylgeranyl diphosphate (GGPP) synthase ggs1, localized outside of the cluster, is proposed to catalyze the first step in nodulisporic acid biosynthesis via conversion of farnesyl pyrophosphate and isopentyl pyrophosphate into geranylgeranyl pyrophosphate (GGPP) (PubMed:29283570).  Condensation of indole-3-glycerol phosphate with GGPP by the prenyl transferase nodC then forms 3-geranylgeranylindole (3-GGI) (PubMed:29283570).  Epoxidation by the FAD-dependent monooxygenase nodM leads to a single-epoxidized-GGI that is substrate of the terpene cyclase nodB for cyclization to yield emindole SB (PubMed:29283570).  The terminal methyl carbon, C28, of emindole SB is then oxidized by the cytochrome P450 monooxygenase nodW to produce nodulisporic acid F (NAF), the pentacyclic core of NAA (PubMed:29283570).  NAF is converted to nodulisporic acid E (NAE) via prenylation.  This step is probably performed by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  Several oxidation steps performed by the FAD-linked oxidoreductase nodO and one of the cytochrome P450 monooxygenase nodR, nodX or nodZ further convert NAE to nodulisporic acid D (NAD) (Probable).  NAD is substrate of cytochrome P450 monooxygenase nodJ to produce the precursor of nodulisporic acid C (NAC), converted to NAC by one of the indole diterpene prenyltransferases nodD1 or nodD2 (Probable).  The FAD-dependent monooxygenase nodY2 then oxidizes NAC to nodulisporic acid B (NAB) (Probable).  Finally NAB is converted to NAA by one of the cytochrome P450 monooxygenases nodR, nodX or nodZ (Probable).
What are the official names of this protein?
Prenyl transferase nodC, Nodulisporic acid biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: DDL_AERHH
Sequence: MKNIHVLLLCGGGGSEHEVSLRSANFLEKQLSLLPGVEVTRVEMFADRWLSADGRECKLGLDKLLSFDSVARPVDYVVPCIHGYPGETGDLQSFLELAGLPYLGCDAEASKICFNKISTKLWLSAIGIPNTPYLFLTEQNDAALSEAKAALAKWGKVFIKAASQGSSVGCYSASNEADLVKGIADAFGYSEQVLIEKAVKPRELEVAVYQYGDELVATYPGEICVPQDKFYTYEEKYSSASHTETALRAEGLTQAQADAIHEYALKAFRQLKLTHLSRIDFFLTEEGEILLNEINTFPGMTSISMFPKLLEHHGHRFADYLEQILRKAV
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_ALBFT
Sequence: MTKFVFVTGGVVSSLGKGIASASLAAILESRGLKVTLIKLDPYLNVDPGTMSPFQHGEVFVTNDGAETDLDLGHYERFVETRMRKANNFTTGQIYKSVLEKERRGDYLGKTVQVIPHVTNEIQDFVKRGAGWGTPDAVDVAIVEIGGTVGDIESLPFLEAVRQMSLKLGPNNSAFVHLSYVPWIAAAGELKTKPTQHTAKQLREIGIQADALLCRADRPIPKEEREKISLFSNVPDWAVISMWDVDTIYKVPRMLHEQGLDGLICDKLRLSTPPANLKRWDDLVYETAHPQGDVNIVMVGKYVELSDSYKSLNEAIRHAGMKNHVRVKIDYIDSETITPDNVTQLAKFDAILVPGGFGIRGVEGKICAARFARENKVPYLGICLGMQVATIEFARHVAGLKDANSTEFDPSSPNPVIALITEWKDADGSIKTRDENSDLGGTMRLGAQSSDVVKGTLAHKIYGDVVTERHRHRYEANVHFLDTLRKAGLVISAFTQREHLTEIVELPQSVHPWFMGVQFHPEFNSTPWAGHPLFIAFIKAALDHQAAGKALKAVA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: LEUC_BACC1
Sequence: MGKRLLDKLWERHVVATNENGLDLLYIDLHLVHEVTSPQAFEGLRLTNRTVRRPDLTFATMDHNIPTKDVWNITDRIAKQQLDTLRENCKQFQVPLADIGDEEQGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPKAMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIQAMEMEERMTLCNMAIEGGAKAGIIAPDEKTVAYVKGRKYAPKDYETFEKKWSELYTDADAMYDLHISIDVTDLAPYVTWGTNPSMGVRIDEKLPEKHDVNDERAFSYMGLSPGQSTYDIPVQHVFIGSCTNSRLSDLEIAASVVKGRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEEAGFEWREPGCSMCLGMNPDQVPEGEHCASTSNRNFEGRQGKGARTHLVSPAMAAAAALYGHFVDIRKESYDGAISYS
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: O166B_CONCL
Sequence: MKLTCVLIAAVLLLAVCQLDSADATGYMRKNPSLRSPKRTRGCKSKGSFCWNGIECCGGNCFFACVY
What are the official names of this protein?
Conotoxin Cl6.6b.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CCF12_ORYSJ
Sequence: MFGPYSGGGGVPLPQMDADTYVRTIAAMPPHPLAPPPDSPRTPHTYVGFLPVFGDLPPLTGAVLQEPVPVPPEQRADQPVAVATENSAPTRPQLCAPYDDEVEATLRAMETNPAERPSPYFLETTQGGRMSALVRASMIAFMGEFSRKNKLADGTLQRAAYFLDRYLSVTPESDDALQLRLVGATAVFLAAKYEDQYTLRKIDASMVAARCGYTSETRHKMVSIMETEMLAALGFNLGGPTAYTFVEHFTRYYGDGEEEKQLKEAAHRVADGTLLTYGFHRYLPSMVAASSIFLARLHELGHEPWSNDLAELTGYKAIDLMGCVCDIYSQIACPRFALLQGKNKRVCKSTSMQGMNMMA
What are the official names of this protein?
Putative cyclin-F1-2, CycF1;2.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin F subfamily.
Protein: PMT6_ARATH
Sequence: MRGSVIGAERSGQTIMVALVLMVGSFYTGSLFGTNQPIYVSHPSSHSASSKFANKIELTYRRLPLVIPESGMNVCPLEFNEYIPCHNVTYVHQLLPSLNLSRREDLERHCPPLEHRLFCLVPPPNDYKIPIRWPTSRDYVWRSNVNHTHLAQVKGGQNWVHEQGQFWWFPGGGTHFKHGAAEYIQRLGNMMTNETGDLRSAGVVQVLDVGCGVASFAAYLLPLGIQTISFAPKDGHENQIQFALERGIGAMISAVATKQLPYPAASFEMVHCSRCRVDWHTNDGILLKEVHRLLRPNGFFVYSSPPAYRKDKEYPMIWDKLVNLTSAMCWKLISRKVQTAIWIKEEKEVCLKQKAELKLISLCDVEDVLKPSWKVPLKDCVQISGQTEERPSSLAERLSAYPATLRKIGISEDEYTSDTVFWREQVNHYWRLMNVNETEVRNVMDMNAFIGGFAAAMNSYPVWVMNIVPATMNDTLSGIFERGLNGAFHDWCEAFSTYPRTYDLVHSDHVFSHYNKSYGDGCLLEDIMLEMDRIVRPQGFVIIRDEEYIISRIRGLAPKFLWEVETHELENKDKKITESVLFCRKRFWAII
What are the official names of this protein?
Probable methyltransferase PMT6.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Protein: ATPD_ECO7I
Sequence: MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVIDGSVRGRLERLADVLQS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y1122_PASMU
Sequence: MNTIKEQEIYKNIDLWESDELGCSKETARISNFSVEDLQKSIQLQSISLRIQKDVLEDLKYIAKSYGIGYQPLMKQILKRFVDAEKQLLLREEVEFKKEFNKKRIYG
What are the official names of this protein?
Uncharacterized protein PM1122.
Protein: H33_CHICK
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes.  Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis.  Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.3, H3.3A/B, Histone H3 class II.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DNAA_MICLC
Sequence: MVADQAVLSSWRSVVGSLEDDARVSARLMGFVYLAQPQGLIGNTLLLAVPNETTRETLQGTQVADALTDALTQEFREEILLAISIDANLQPPRTPSSEARRSSLAGGPSGAAAPDVELPPAATAATSRRAVAEELPGFRIEPPADVVPAANAAPNGNGKPTPAPPSTSAETSRLNDRYHFETFVIGSSNRFAHAAANAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYARRLYPGLRVRYVNSEEFTNDFINSIRHDEGASFKQVYRNVDILLIDDIQFLADKEATVEEFFHTFNTLYNNNKQVVITSDLPPKQLSGFEDRLRSRFEWGLITDIQPPDLETRIAILRKKAEAEGLVAPPEALEYIASRISTNIRELEGALIRVTAFASLNRQTVDIELAEHVLKDLITDETAHEITPELILHATGEYFNLTLEELTSKSRTRTLVTARQIAMYLLRELTEMSLPKIGQVLGGRDHTTVIHADRKIRELMAERRTIYNQVTELTNEIKRKQRGA
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B3_USTMD
Sequence: MSRDPKLSLSKFLECLNEIEHEFLRDKVEHRPVLVRKLQELQQKTPKHVAKLPHEPEMIQQIHQAAHRIDIVAQAFIRFDQKFVSLCSEIVHDTTKVMQEANVVSPGEGCRNLSEDLPAYHMRNHFLHTLENPYPTQEEKEGLVRLTNESTARIRPSNAIRPPLEVHQLTLWFINARRRSGWSHILKKFAREDPSRMKRLVRAKLSSSNQSTPPSLTSEKPSDDLDVVLSDNLGRPLTLADKQQFEDDWASMISWIKYGVKEKVGDWVYDLCAASKKTPKPGMPRPVTTVAKRHPARKTKPAAKPKSRTANPRASTTPSIDSTLDSSKLESTPELSMCSTADTSFSTFGSSLSMSHYNPFQDGNDILQSPTVKARGNRKVKALPKRAGKQQPDEVDNGKIPFLCLSVAFV
What is the function of this protein?
The B locus has at least 25 alleles, and any combination of two different B alleles yields a multimeric regulatory protein, that activates genes responsible for the pathogenicity and for the sexual development of the fungus within the corn plant.
What are the official names of this protein?
Mating-type locus allele B3 protein.
What is the protein family that this protein belongs to?
Belongs to the TALE/M-ATYP homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CSPA_KLEAK
Sequence: MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKSLDEGQKVSFTIESGAKGPAAGNVTSL
What are the official names of this protein?
Major cold shock protein.
What are the subcellular locations of this protein?
Cytoplasm.