PharMolix/UniProtQA huggingface dataset:
Protein: NU6C_SOLLC
Sequence: MDLSEPIHDFLLVFLGSGLILGGLGVVLLPNPIYSAFSLGLVLVCTSLFYILSNAYFVAAAQLLIYVGAINVLIIFAVMFMNGSEYYKDFHLWTVGDGITSMVCISLFISLITTISDTSWYGIIWTTRSNQIIEQDFLSNSQQIGIHLSTDFFLPFELISIILLVALIGAIAVARQ
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 6, chloroplastic, NAD(P)H dehydrogenase subunit 6, NADH-plastoquinone oxidoreductase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RR9_EMIHU
Sequence: MSTISYTAVGRRKEATAKVKLQPGTGIITVNKKPGETYFNYNSEYLSTLRGPLLALGLENDYDLHITAKGGGIKGQTDAVKLGLARAICTMSSEKRESLKPHGYLTRDYRAKERKKYGLRKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TYSY_CANAL
Sequence: MTVSPNTAEQAYLDLCKRIIDEGEHRPDRTGTGTKSLFAPPQLRFDLSNDTFPLLTTKKVFSKGIIHELLWFVAGSTDAKILSEKGVKIWEGNGSREFLDKLGLTHRREGDLGPVYGFQWRHFGAEYKDCDSDYTGQGFDQLQDVIKKLKTNPYDRRIIMSAWNPPDFAKMALPPCHVFCQFYVNFPTSSPDPNNPKQAKTAKPKLSCLLYQRSCDMGLGVPFNIASYALLTKMIAHVVDMDCGEFIHTLGDAHVYLDHIDALKEQFERIPKQFPKLVIKEERKNEIKSIDDFKFEDFEIVGYEPYPPIKMKMSV
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.
Protein: ASR_YERPP
Sequence: MKKVLALMVAATLGLSSVAFAADTTATATPAATSTTATVAAQTKATQHQKHKVTKKTTEQKAQAAKKHEKKASVQKTPVQKAQAAKKHVKKASVQKAPVQKAQAAKKHHKTAKKPVAAPAA
What is the function of this protein?
Required for growth and/or survival at acidic conditions.
What are the official names of this protein?
Acid shock protein.
What is the protein family that this protein belongs to?
Belongs to the Asr family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSD_PHOPR
Sequence: MLDNIKIGLQYCTPKHALTRLVGKLASLEAGKLTTAIIRWFIGQYKVDMSEARNPDPAAYSTFNHFFIRELKEGARPINNDDNIISHPADACVSQLGPIKEGRLFQAKGHYFDACELLGGDKALAEEFVDGDFATLYLSPRDYHRVHMPCDGTLRQMIYVPGDLFSVNPLTAQNVPNLFARNERVVCIFDTAHGPIAQVLVGATIVGSIETVWAGTVTPPTGPEVRRWDYPATGTQAIVLKKGQEMGRFKLGSTVINLFPKDMVRFVEAMKPEQPTRMGEPYAELDSSEKE
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TDT_BOVIN
Sequence: MDPLCTASSGPRKKRPRQVGASMASPPHDIKFQNLVLFILEKKMGTTRRNFLMELARRKGFRVENELSDSVTHIVAENNSGSEVLEWLQVQNIRASSQLELLDVSWLIESMGAGKPVEITGKHQLVVRTDYSATPNPGFQKTPPLAVKKISQYACQRKTTLNNYNHIFTDAFEILAENSEFKENEVSYVTFMRAASVLKSLPFTIISMKDTEGIPCLGDKVKCIIEEIIEDGESSEVKAVLNDERYQSFKLFTSVFGVGLKTSEKWFRMGFRSLSKIMSDKTLKFTKMQKAGFLYYEDLVSCVTRAEAEAVGVLVKEAVWAFLPDAFVTMTGGFRRGKKIGHDVDFLITSPGSAEDEEQLLPKVINLWEKKGLLLYYDLVESTFEKFKLPSRQVDTLDHFQKCFLILKLHHQRVDSSKSNQQEGKTWKAIRVDLVMCPYENRAFALLGWTGSRQFERDIRRYATHERKMMLDNHALYDKTKRVFLKAESEEEIFAHLGLDYIEPWERNA
What is the function of this protein?
Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator (PubMed:3755527).  One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
What are the official names of this protein?
DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, TDT, Terminal transferase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-X family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCA10_XENTR
Sequence: MEGGTNDGAAVPGNGAGTAGSIFWWLKNRCLGRGLCVDPARDNFRTMTSLYSSIHPADSVNLSTRTHGAVFNLEYSPDGSVLTVACEQTEVLLFDPVSSKHIKTLSEAHEDCVNNIRFLDNRMFATCSDDTTIALWDLRKLNSKVCTLHGHTSWVKNIEYDTNTRLLVTSGFDGNVIIWDTNRCTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHELDLTKSLEVGSYPILRARRTASTSDMTSTSSDTRPSSSPCHNSDLGPLFEKHMSRSSQREGASPRNSLEVLTPEVPGERDRGNCITSLQLHPKGWATLLRCSSNTDDQEWTCVYEFQEGAPVRQVSPRCSLRLTHYIEEANVGRGYIKELCFSPDGRMIASPYAYGIRLLGFDSQCKELVDCLPKEAGTLQVIRSLYSHKDVVLTTKFSPTHCQIASGCLSGRVTLYQPKF
What is the function of this protein?
May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
What are the official names of this protein?
DDB1- and CUL4-associated factor 10, WD repeat-containing protein 32.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DCAF10 family.
Protein: PDXJ_LARHH
Sequence: MILLGVNIDHVATLRNARGTRYPSPVEAALVAETAGADLITLHLREDRRHIKDDDLAVMRAAIKTRMNLEMALTDEMLDNALRVLPQDVCIVPEKREELTTEGGLDVIRYFDRIADFTRQLQAKGIRVSLFIDPDDEQIKASHETGATVVELHTGRYADAESHDIRQRELTRIRHAAIVGVDLGLVVNAGHGLSYHNVQPVAAIREIRELNIGHAIVAHALMVGFAPAVREMKALMVEARHNAA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYRC_BOVIN
Sequence: MDALVAHCSARLLQQEKEIKFLTAEVDRLKNYSCSEASADLEKLREENLKLKYRLNILRKSLQAERNKPTKTMININSCLEEVFGCAIKAAYPVLENPPLIVTPSQQPKFGDYQCNSAMGICQMLKTKEQKVNPREIAENIVKHLPDNEYIEKVEIAGPGFINIHLRKGFVSQQLTNLLVNGVKIPSIGENKKVIVDFSSPNIAKEMHVGHLRSTIIGESMCRLFEFAGYNVLRLNHVGDWGTQFGMLIAHLQDKFPDYLTVSPPIGDLQAFYKESKKRFDTEEEFKKRAYQCVVLLQSKNPDIIKAWKLICDVSRQEFNKIYEALDISLIERGESFYQDRMHDIVKEFEDRGFVQVDDGRKIVFVPGCSVPLTIVKSDGGYTYDTSDLAAIKQRLFEEKADMIIYVVDNGQSLHFQTVFGAAQMIGWYDPAVTRVSHAGFGVVLGEDKKKFKTRSGETVRLIDLLEEGLKRSMDKLKEKERDKVLTTEELKAAQTSVAYGCIKYADLSHNRLNDYIFSFDKMLDDRGNTAAYLLYAFTRIRSIARLANIDEEMLRKAAHETEIILDHEKEWKLGRCILRFPEVLQKILDDLLLHTLCDYIYELATTFTEFYDSCYCVEKDRQSGEVLKVNMWRMLLCEAVAAVMAKGFDILGIKPVQRM
What is the function of this protein?
Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis.  Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1.
What are the official names of this protein?
Arginine--tRNA ligase, cytoplasmic, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol.
Protein: INS_TRADO
Sequence: AANQHLCGSHLVEALYLVCGERGFFYSPKAGIVEQCCHNTCSLYQLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
What are the official names of this protein?
Insulin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR7_DRANE
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRALKKIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSMH_EHRCJ
Sequence: MHTPVLLKEMLEILDPQDGKIYVDATFGAGGYTKAILNAANCKVCAIDQDKHTSIFYEELANNFPNRIHFFINKFSQIKQVLLGAQLERVDGVVFDIGVSSMQLDDANRGFSFSKNGPLDMRMSTSNSIDASVFVNTVSEEEIANIIYQYGGEKYSRKIAKAIINFRKKKVIETTGELASIVRSVVSRSKNHDINPATRTFQAIRIWVNKELQELEQGIMCAADLLNPGGKIIVVSFHSLEDRIVKMIFKSLCSDEISLKLNTGFQLINKKIVRPSFEEILNNPRSRSAKLRAILKI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TNNI3_RAT
Sequence: MADESSDAAGEPQPAPAPVRRRSSANYRAYATEPHAKKKSKISASRKLQLKTLMLQIAKQEMEREAEERRGEKGRVLSTRCQPLVLDGLGFEELQDLCRQLHARVDKVDEERYDVEAKVTKNITEIADLTQKIYDLRGKFKRPTLRRVRISADAMMQALLGTRAKESLDLRAHLKQVKKEDIEKENREVGDWRKNIDALSGMEGRKKKFEG
What is the function of this protein?
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
What are the official names of this protein?
Troponin I, cardiac muscle, Cardiac troponin I.
What is the protein family that this protein belongs to?
Belongs to the troponin I family.
Protein: H20A3_CYRHA
Sequence: MKSATLLALSFLLIASCFLICEAEHSRYEEHEILEENMGDVVNLEQRSCAKPGEMCMRIKCCDGQCGCNRGTGRCFCK
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XX.3, HNTX-XX.3, Peptide F8-26.11.
What is the protein family that this protein belongs to?
Belongs to the hainantoxin family. 20 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: REPM_STAAU
Sequence: MSKNNYTNHSNHLENHDSDNFSKTGYSNSRLDAHFVCTSNPKLSFDAMTIVGNLNKNSAKKLSDFMSLDPQIRLWDILQTKFKAKALQEKVYIEYDKVKADTWDRRNMRVEFNPNKLTHDEMLWLKHNIIDYMEDDGFTRLDLAFDFEDDLSDYYALSEKALKRTVFFGTTGKAETKYFGSRDSNRFIRIYNKKKERKENADVDVSAEHLWRVEIELKRDMVDYWNNCFNDLHILKPAWATLESLKEQAMVYLLLHEESKWGELHRNSRRKYKQIIQEISSIDLTDLMKSTLTDNEENLQKQINFWQRKFEFWK
What is the function of this protein?
This protein is probably a specific topoisomerase involved in initiating replication.  This protein is specifically required and may be rate-limiting for replication of the plasmid in vivo.
What are the official names of this protein?
Replication initiation protein.
What is the protein family that this protein belongs to?
Belongs to the plasmid replication initiation factor family.
Protein: Y364_MYCTU
Sequence: MSTAVTAMPDILDPMYWLGANGVFGSAVLPGILIIVFIETGLLFPLLPGESLLFTGGLLSASPAPPVTIGVLAPCVALVAVLGDQTAYFIGRRIGPALFKKEDSRFFKKHYVTESHAFFEKYGKWTIILARFVPIARTFVPVIAGVSYMRYPVFLGFDIVGGVAWGAGVTLAGYFLGSVPFVHMNFQLIILAIVFVSLLPALVSAARVYRARRNAPQSDPDPLVLPE
What are the official names of this protein?
Uncharacterized membrane protein Rv0364.
What is the protein family that this protein belongs to?
Belongs to the DedA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HPRK_NEIM0
Sequence: MPSISVRRLFDDNQYKLQLAWAAGNSGADNRIGVEADKPVLALVGHLNFIHPNQIQVVGLAESEYLNRLESGETGYQFGDLFDISMSLVIVANGLPVSPGLRDYCHKNDIPLLTSKLESPYLMDVLRIYLQRTLAASSVKHGVFLDVFEIGVLITGHSGLGKSELALELISRGHSLIADDAVELFRIGPETLEGRCSPMLRDFLEVRGLGILNIRHIFGETSIRPKKILQLIINLVEADDEYMKQLDRLSIRTETESILNVNVRSVTLPVAVGRNLAVLVEAAVRNYILQLRGKDSTREFLERHQTQLKENEQNHENRPD
What is the function of this protein?
Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS).  HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
What are the official names of this protein?
HPr kinase/phosphorylase, HPrK/P, HPr(Ser) kinase/phosphorylase.
What is the protein family that this protein belongs to?
Belongs to the HPrK/P family.
Protein: MYG_MACFA
Sequence: MGLSDGEWQLVLNVWGKVEADIPSHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGVTVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLELISESIIQVLQSKHPGDFGADAQGAMNKALELFRNDMAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS11_VIBVY
Sequence: MAKQPTRARKRVRKQVADGVAHIHASFNNTIVTITDRQGNALAWATAGGSGFRGSRKSTPFAAQVAAERCAEMAKEYGLKNLEVMVKGPGPGRESTVRALNAAGFRITNIVDATPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FMC1_BOVIN
Sequence: MAALGSPLRTWRGLLRELRYLNAATGRPYRDTAAYRYLVKAFRAHRVTSEKLCRAQHELHFQAATYLCLLRSIREHVALHQEFHGKGERSVEESAGLVGLKLPQQPGGKGWEP
What is the function of this protein?
Plays a role in the assembly/stability of the mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V).
What are the official names of this protein?
Protein FMC1 homolog.
What is the protein family that this protein belongs to?
Belongs to the FMC1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MDTG_ENTLS
Sequence: MYSSDAPINWKRNLTITWIGCFLTGAAFSLVMPFLPLYVESLGVTGHSALNMWSGLVFSITFLFSAIASPFWGGLADRKGRKIMLLRSALGMAIVMLLMGLAQNIWQFLILRALLGLLGGFIPNANALIATQIPRHKSGWALGTLSTGGVSGALLGPLVGGVLADSYGLRPVFFMTASVLFLCFLLTLLFIREQFQPVAKKEMLHAREVIASLKSPKLVLSLFVTTLIIQVATGSIAPILTLYVRDLAGNVANIAFISGMIASVPGVAALISAPRLGKLGDRIGPEKILIAALVISVLLLIPMSFVQTPWQLGLLRFLLGAADGALLPAVQTLLVYNATNQIAGRVFSYNQSFRDIGNVTGPLIGASVSANYGFRAVFLVTAMVVLFNAVYTGLSLRRTGATALPAQDVEKDDTSLVR
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS4_ARTS2
Sequence: MANNTRARRTARLSRALGIALTPKAAKYMERRPYGPGEHGRARKKQDSDYAVRLREKQRLRAQYGIREAQMTRAFEEARRTKGLTGENLIELLEMRLDALVLRAGFARTIAQARQLVVHRHILVDGIRVDRPSFRVGEGQLVHVHSRSETMPPFQVAAAGAHRDVLPQVPAYLDVKLDALQARLVRRPKRSEVPVTCEEQLVVEFYAR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: TD2_SOLLC
Sequence: MEFLCLAPTRSFSTNPKLTKSIPSDHTSTTSRIFTYQNMRGSTMRPLALPLKMSPIVSVPDITAPVENVPAILPKVVPGELIVNKPTGGDSDELFQYLVDILASPVYDVAIESPLELAEKLSDRLGVNFYIKREDKQRVFSFKLRGAYNMMSNLSREELDKGVITASAGNHAQGVALAGQRLNCVAKIVMPTTTPQIKIDAVRALGGDVVLYGKTFDEAQTHALELSEKDGLKYIPPFDDPGVIKGQGTIGTEINRQLKDIHAVFIPVGGGGLIAGVATFFKQIAPNTKIIGVEPYGAASMTLSLHEGHRVKLSNVDTFADGVAVALVGEYTFAKCQELIDGMVLVANDGISAAIKDVYDEGRNILETSGAVAIAGAAAYCEFYKIKNENIVAIASGANMDFSKLHKVTELAGLGSGKEALLATFMVEQQGSFKTFVGLVGSLNFTELTYRFTSERKNALILYRVNVDKESDLEKMIEDMKSSNMTTLNLSHNELVVDHLKHLVGGSANISDEIFGEFIVPEKAETLKTFLDAFSPRWNITLCRYRNQGDINASLLMGFQVPQAEMDEFKNQADKLGYPYELDNYNEAFNLVVSE
What is the function of this protein?
Involved in defense against lepidopteran, but not coleopteran herbivore insects (PubMed:21436043, PubMed:17416643).  Acts in the insect gut to degrade threonine, which is an essential and limiting nutrient for the growth of lepidopteran larvae (Probable).  Active against both L-threonine and L-serine (PubMed:17416643).
What are the official names of this protein?
Threonine dehydratase 2 biosynthetic, chloroplastic, SlTD2, Threonine deaminase 2.
What is the protein family that this protein belongs to?
Belongs to the serine/threonine dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MIAB_MOOTA
Sequence: MVKARKTFKIITYGCQMNQRDSEMMADLLQDAGYEPVAREEEAGVIILDTCCVREKAENKVYGKLGQIEKLKSANPDLVIAVAGCMVQQPGVAEKIRQQAPYVDLLLGTGNLQELPQLIEEIKAMHRPRIVVGEQEGPVVEDLPRRRARGAQAFVTITYGCNNFCTYCIVPYVRGRERSRRPENIIKEVKELVDQGVIEVTLLGQNVNSYGRDLRDGINFAGLLERVNAVEGLKRIRYVTSHPRDFTPELVTTISRLDKVCEHVHLPVQAGSNRILELMHRGYTREHYLELVADLRRHIPGISLTTDLIVGFPGETEADFEDTLDLVARVQFDNAFTFMYSPRRGTEAATMPGQLPTAIKKERLKRLMELQNSISLAKNEALVGQEVEVLVEGPSKTDPDQLSGRTRTNKLIIFPGDQSLTGRLVRVRLTRAQTWLLKGEMVDG
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_BRUSU
Sequence: MSEQDKKQAAIKAAQAAADAVREAQAALAEEGRLLFKKSWIFIRGVPSMKFLPPEGPVEIAFAGRSNVGKSSLINALVGKKGLARTSNTPGRTQELNYFVPDGYSGENGDLPPLALVDMPGYGFAEAPKAQVDAWTRLVFDYLRGRTTLKRVYVLIDARHGIKKNDAEVLDLLDKAAVSYQIVLTKIDKIKPAGVPRLLEETHKLTYKRAACFPGIIATSSEKGQGLDDLRAAIALLLKEY
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: VP7_ROT41
Sequence: MYGIEYTTVLTFLISFILLNYILKSLTRMMDFVIYRFLFVIVVLSPLLKAQNYGINLPITGSMDTAYANSTQEETFLTSTLCLYYPTEAATEINDNSWKDTLSQLFLTKGWPTGSIYFREYTDIVSFSVDPQLYCDYNVVLMKYDAALQLDMSELADLILNEWLCNPMDITLYYYQQTDEANKWISMGSSCTIKVCPLNTQTLGIGCLTTDTATFEEVATAEKLVITDVVDGVNHKLDVTTATCTIRNCKKLGPRENVAVIQVGGSDVLDITADPTTAPQTERMMRINWKKWWQVFYTVVDYVNQIIQLMSKRSRSLNSAAFYYRV
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.
Protein: RING1_MACMU
Sequence: MDGTEIAVSPRSLHSELMCPICLDMLKNTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRPDPNFDALISKIYPSREEYEAHQDRVLIRLSRLHNQQALSSSIEEGLRMQAMHRAQRVRRPIPGSDQTTTMSGGEGEPGEGEGDGEDVSSDSAPDSAPGPAPKRPRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSPPEPGGEIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLALRIALERRQQQEAGEPGGPGGGASDTGGPDGGGGEGGGAGGGDGPEEPALPSLEGVSEKQYTIYIAPGGGAFTTLNGSLTLELVNEKFWKVSRPLELCYAPTKDPK
What is the function of this protein?
Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation.  H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals.  Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.  Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RING1, Polycomb complex protein RING1, RING finger protein 1, RING-type E3 ubiquitin transferase RING1.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: NDUBA_SOLTU
Sequence: GRKKGVQFDEGAPDDFDPNNPYKKDVAFL
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB10 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CRCB1_SYNS9
Sequence: MAGSALEALLVGIGAIPGAWLRLKAVNHFEPMVPKKHWGTFAVNVIACFGLGLVLALYQSCSAKTGLALLIGVGFFGSLSTFSTFAVELLNELRAGRPFVSLVLALASIAAGLCAAGVGYGLGAYG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.