PharMolix/UniProtQA huggingface dataset:
Protein: EFUC_HORCR
Sequence: MSAPRTALSSARQLSNGLIRRTNPRKRFLPLPSTVRSFTNNKPLRSQATAAQEPIVESERPSPVTSVNQPLSFPCLDALDTKTQSLTKQKKSLSGPEPSYAAGETEHFHSASPILLDWGGVLPEFDIAYETWGTLNADKSNAILLHTGLSASSHAKSTAKNPKPGWWEKFIGPGAPLDTDKYHIICTNVLGGCYGSTGPSSIDPLAENNTSSAQKDRYATRFPILTMQDMVRAQFRLLDWMGIDALYASVGSSMGGMQSLAACVLEPSRVGKVVSVSGCARSHPYSIAMRHTQRQVLMNDPAWSSTRGNYYPSIPPHAGMKLAREIATVTYRSGPEWEQRFGRRRADPSKPPALCPDFLIETYLDHAGEKWCLEYDANSLLYVSKAMDLFDLGDEHMRTLDGVRKSNAWKLDGFAAGTAKEEEKAGLCNLTLPDTPYEEQDETSSELLASSPEEAKRARETSSAALIAEEPPEDLVKGLQALSGTPALVMGVASDILFPAWQQREIAAALRKAGNRRVTHVELGEDRSLFGHDTFLLDLEGVGGEIRRFLG
What is the function of this protein?
Acetyltransferase; part of the gene cluster that mediates the biosynthesis of enfumafungin, a glycosylated fernene-type triterpenoid with potent antifungal activity, mediated by its interaction with beta-1,3-glucan synthase and the fungal cell wall (PubMed:30051576).  The pathway begins with the terpene cyclase-glycosyl transferase fusion protein that most likely uses 2,3-oxidosqualene as substrate and catalyzes glycosylation immediately after cyclization (Probable).  The fernene glycoside then could be processed by the desaturase efuI which catalyzes isomerization of a double bond established by efuA to form the core structure (Probable).  The latter would then undergo a series of hydroxylations in unknown order at C-2, C-19, C-23 and C-25, which would be catalyzed by two of the three cytochrome P450 monooxygenases efuB, efuG or efuH (Probable).  The hydroxy-group at C-25 becomes oxidized by the dehydrogenase efuE to enable a spontaneous, non-enzymatic hemiacetal formation with C-23 (Probable).  After hydroxylation at C-2, acetylation by the acetyltransferase efuC takes place (Probable).  The final steps in enfumafungin biosynthesis require expansion of the 5-membered ring by lactonization via a Baeyer-Villiger reaction mediated by one of the BGC's cytochrome P450 monooxygenases (efuB, efuG or efuH) followed by ring cleavage (Probable).  This type of reaction would establish a double bond between C-20 and C-21 which could be reduced by the reductase efuL to form the final product (Probable).
What are the official names of this protein?
Acetyltransferase efuC, Enfumafungin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
Protein: EFG_STRPZ
Sequence: MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQESREKLIEAVAETDEDLMMKYLEGEEITNDELIAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIAYLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKSKADQDKMGVALQKLAEEDPTFRVETNVETGETVIAGMGELHLDVLVDRMKREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLYDGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKTKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYN_STRPD
Sequence: MSKKLISIVDVKDYVGQEVTIGAWVANKSGKGKIAFVQLRDGSAFFQGVAFKPNFIEKYGEESGLEKFDVIKRLNQETSVYVTGIVKEDERSKFGYELDITDLEIIGESHEYPITPKEHGTDFLMDNRHLWLRSRKQMAVMQIRNAIIYATYEFFDQNGFIKFDSPILSENAAEDSTELFETDYFGKPAFLSQSGQLYLEAGAMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYSFLSHEESLDLQEAYVKALIQGVLDRAPQALDILERDVEALKRYITEPFKRVSYDDAITLLQEHEADEDTDYEHLEHGDDFGSPHETWISNYFGVPTFVVNYPASFKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREDNYDALVAKMDELGMDKSEYDFYLDLRKYGSVPHGGFGIGIERMVTFVAGTKHIREAIPFPRMLHRIRP
What are the official names of this protein?
Asparagine--tRNA ligase, Asparaginyl-tRNA synthetase, AsnRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THII_STRU0
Sequence: MQYSEIMVRHGELSTKGKNRMRFINKLKRNIQEVLSPFPNIKVRSDRDRTHVFLNGTPYEPVAEALKNVFGIQAFNPVYKLEKNVDLLIASVQEIMKDLYVDGMTFKISSKRSDHHFELDSRDLNLVLGNAVFDVLPNIKAQMKKPDVNLKVEIRDEAAYISHEEIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVEIEAVHFASPPYTSPGALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKDKAPEAYLMTLTRRFMMRITDAIRASRSGLVIVNGESLGQVASQTLESMQAINAVTATPVIRPVVTMDKLEIIELAEKIDTFSISIQPFEDCCTIFAPDRPKTNPKLKNVEEYEKRFDIDGLVQRAVKGIKITEIKPEAEADDVDLMLDALL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARB_CAUVC
Sequence: MESVVVGEPGMSEGRRGLGRGLSALLGEVDAAPAQAPGEQLGGSREAPIEILQRNPDQPRRTFREEDLEDLSNSIREKGVLQPILVRPSPDTAGEYQIVAGERRWRAAQRAGLKTVPIMVRELDDLAVLEIGIIENVQRADLNVLEEALSYKVLMEKFERTQENIAQTIGKSRSHVANTMRLLALPDEVQSYLVSGELTAGHARAIAAAADPVALAKQIIEGGLSVRETEALARKAPNLSAGKSKGGRPPRVKDTDTQALESDLSSVLGLDVSIDHRGSTGTLTITYATLEQLDDLCNRLTRGI
What is the function of this protein?
Involved in chromosome partition.  Localize to both poles of the predivisional cell following completion of DNA replication.  Binds to the DNA origin of replication.
What are the official names of this protein?
Chromosome-partitioning protein ParB.
What is the protein family that this protein belongs to?
Belongs to the ParB family.
Protein: MINC_PSEU2
Sequence: MSQIESQNPEPVFQLKGSMLAITVMELARTNLEALDRQLAAKVAQAPNFFSNTPLILALDKLAPNEGPVDLPGLVRICRQHGLRTLAIRANRIEDIAAAIAVDLPVLPPSGARERVIDPVEAEAPKKIPEKPPEPLIKPTRVITAPVRGGQQIYAQGGDLVVVAPVSPGAELLADGNIHVYGPMRGRALAGIKGDTKARIFCQQLSAELISIAGQYKVSEDLRRDPLWGSPVQISLSGDVLNIIRL
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ATPF_HELP2
Sequence: MFVVKMVLGFLILLSPLCATGLDISQTDIIERSLNFLLFVGILWYFLAKKLRSFLRSKSLEISKRLEEIQAQLKVSKENKKKLLKELEQAKEKAELIISDANKEAYTITQKYELQTKMDVENLIKNSKALMDLEVKKIKRELVESVFKDLRESKKVSFNAQDCVNILKQRL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ARCA_ALIF1
Sequence: MNKLFVGSEIGQLRRVILHRPERALSHLTPTNCHNLLFDDVLSVEKALLEHDQFVKTLENQDVDVLLLQDLLEQTLENPEAKEWLLKHQISHYRFGPTFANQIRVFLLEHSNKELASILLGGLAFIELPFKAPSMLQQLSDPFDFVIAPLPNHLFTRDTSCWIYGGVSINPMAKAARKRESNHLRAIYRWHPLFSHHDFARYFEDENRYYDNATIEGGDVLVIGKGNVLVGISERTTPQGIENLAKQLFRTHQAKQVIAIKLPEDRSCMHLDTVMTHMDHNVFSVYPRVIDKNMGCWSITPCGEQHLDIKEMPNFQNVLMSALELDNLNIITTGGDSYEAEREQWHDANNVLTIKPGVVVAYERNTYTNEKYDKAGIHVLPITGDELGRGRGGARCMSCPIERDGI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEC12_CAEEL
Sequence: MACKNPKKFFPIRKSPVLRDGAFKGKLVLVTGGGTGIGKAIATTFAHLRATVVIAARRMEKLEQTARDITKITGGTCEPFQMDIKDPGMVSDAFDKIDMKFGKVPEILVNNAAGNFIMATELLSSNAYGTIIDIVLKGTFNVTTELGKRCIQNKTGASITSITAGYARAGAPFIVPSAVSKAGVETMTKSLATEWSKYGLRFNAVSPGPIPTKGAWGRLNSGEMGDIAEKMKFLNPEGRVGSPEEVANLVAFISSDHMSFLNGAIIDLDGGQQHFNHGSHMGDFLHSWDHKNWEDAENLIRGRTGKEKA
What is the function of this protein?
Auxiliary enzyme of beta-oxidation.  It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions.  Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
What are the official names of this protein?
Probable 2,4-dienoyl-CoA reductase decr-1.2 [(3E)-enoyl-CoA-producing].
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
Protein: CXAT5_CONMS
Sequence: MPKLAVVLLVLLILPLSYFDAAGGQAAEGDRRGNGLARYLQRGGRDNEAECQINTPGSSWGKCCLTRMCGPMCCARSGCTCVYHWRRGHGCSCPG
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Ms20.5.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HFQ_PSEA8
Sequence: MSKGHSLQDPYLNTLRKERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVRLPSGDQPAEPGNA
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: CLPB_AGRFC
Sequence: MNIDKYSERVRGFLQSAQTFALAENHQQFSPEHVLKVLLDDEQGMAASLIERAGGDAKEARLANDAALAKLPKVSGGNGGLSLTAPLAKVFSTAEDLAKKAGDSFVTVERLLQALAIESSASTSASLKKAGATAQALNQVINDIRKGRTADSANAEQGFDALKKYARDLTEEAREGRLDPVIGRDDEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLKDKKLMALDMGALIAGAKYRGEFEERLKAVLNEVQAENGGIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEYRKHVEKDPALARRFQPVLVDEPNVEDTISILRGLKEKYEQHHKVRISDSALVAAATLSNRYITDRFLPDKAIDLMDEAASRLRMQVDSKPEELDELDRRIIQLKIEREALKQETDQSSVDRLRKLEDELADTEEKADALTARWQAEKQKLGHAADLKKRLDEARNELAIAQRNGQFQRAGELTYGIIPGLEKELAAAEARDSSGAGSMVQEVVTPDNIAHVVSRWTGIPVDKMLEGQREKLLRMEDELAKSVVGQGEAVQAVSKAVRRSRAGLQDPNRPIGSFIFLGPTGVGKTELTKSLARFLFDDETAMVRLDMSEYMEKHSVARLIGAPPGYVGYEEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFKNTIIIMTSNLGSEFMTQMGDNDDVDSVRELVMERVRSHFRPEFLNRIDDIILFHRLRRDEMGAIVEIQLKRLVSLLADRKITLELDEDARSWLANKGYDPAYGARPLKRVIQKSVQDRLAEMILGGEIPDGSRVKVTSGTDRLLFKVKPAKGEAETETADAA
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS7_METMA
Sequence: MRISKISRKTKETDIQLEINLDGKGTADVSTGIGFFDHMLSSFARHAEFDLKVRAEGDLYVDEHHLIEDTGIVLGKALAEALGDMAGIARFGEARIPMDEALAEVALDVGGRSYLVMKADFIAPQVGQFSTQLVKHFFETVASNAKITIHASVYGDNDHHKIEALFKAFAYAMKRAVKIEGKEVKSTKGTL
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_HELPJ
Sequence: MQKQHQRQHKVELVANLKSQFDSAKALLICDYKGLSVKKLEALRNKARIQGIKVQVIKNTLAHIAMKEVGCADLDLKETNVFLWGDDQIALSKLVFDFQKEHKDHFVLKAGLFDKESVSVAHVEAVSKLPSKEELMGMLLSVWTAPARYFVTGLDNLRKAKEEN
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: XTH22_ARATH
Sequence: MAITYLLPLFLSLIITSSVSANFQRDVEITWGDGRGQIKNNGELLTLSLDKSSGSGFQSKNEYLFGKVSMQMKLVPGNSAGTVTTLYLKSPGTTWDEIDFEFLGNSSGEPYTLHTNVYTQGKGDKEQQFKLWFDPTANFHTYTILWNPQRIIFTVDGTPIREFKNMESLGTLFPKNKPMRMYSSLWNADDWATRGGLVKTDWSKAPFTASYRGFQQEACVWSNGKSSCPNASKQGTTTGSWLSQELDSTAQQRMRWVQRNYMIYNYCTDAKRFPQGLPKECLAA
What is the function of this protein?
Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET).  Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues.  Its induction in case of mechanical stress, suggests that it may contribute in the adaptive changes in morphogenesis by being recruited to alter tissues tensil strength, or flexibility, enabling adaptation to mechanically stressful environments.
What are the official names of this protein?
Xyloglucan endotransglucosylase/hydrolase protein 22, At-XTH22, XTH-22, Touch protein 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 16 family. XTH group 2 subfamily.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: PP350_ARATH
Sequence: MAATLLSQCYRIYNSDACKCVSSENHQTTGKRNGNRNLEFDSGISKPARLVLRDRYKVTKQVNDPALTRALRGFADSRLMEDALQLFDEMNKADAFLWNVMIKGFTSCGLYIEAVQFYSRMVFAGVKADTFTYPFVIKSVAGISSLEEGKKIHAMVIKLGFVSDVYVCNSLISLYMKLGCAWDAEKVFEEMPERDIVSWNSMISGYLALGDGFSSLMLFKEMLKCGFKPDRFSTMSALGACSHVYSPKMGKEIHCHAVRSRIETGDVMVMTSILDMYSKYGEVSYAERIFNGMIQRNIVAWNVMIGCYARNGRVTDAFLCFQKMSEQNGLQPDVITSINLLPASAILEGRTIHGYAMRRGFLPHMVLETALIDMYGECGQLKSAEVIFDRMAEKNVISWNSIIAAYVQNGKNYSALELFQELWDSSLVPDSTTIASILPAYAESLSLSEGREIHAYIVKSRYWSNTIILNSLVHMYAMCGDLEDARKCFNHILLKDVVSWNSIIMAYAVHGFGRISVWLFSEMIASRVNPNKSTFASLLAACSISGMVDEGWEYFESMKREYGIDPGIEHYGCMLDLIGRTGNFSAAKRFLEEMPFVPTARIWGSLLNASRNHKDITIAEFAAEQIFKMEHDNTGCYVLLLNMYAEAGRWEDVNRIKLLMESKGISRTSSRSTVEAKGKSHVFTNGDRSHVATNKIYEVLDVVSRMVGEEDIYVHCVSRLRPETLVKSRSNSPRRHSVRLATCFGLISTETGRRVTVRNNTRICRKCHEFLEKASRLTRREIVVGDSKIFHHFSNGRCSCGNYW
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At4g35130, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PPR family. PCMP-H subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: INSE3_ECOLI
Sequence: MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYESQLYNWRSKQQNQQTSSERELEMSTEIARLKRQLAERDEELAILQKAATYFAKRLK
What is the function of this protein?
Involved in the transposition of the insertion sequence IS3.
What are the official names of this protein?
Transposase InsE for insertion sequence IS3C.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: AGL8_SOLTU
Sequence: MGRGRVQLKRIENKINRQVTFSKRRSGLLKKAHEISVLCDAEVGLIVFSTKGKLFEYANDSCMERLLERYERYSFAERQLVPTDHTSPGSWTLEHAKLKARLEVLQRNQKHYVGEDLESLNMKELQNLEHQLDSALKHIRSRKNQLMHESISVLQKQDRALQEQNNQLSKKVKEREKEVAQQNQWDQQNHEINSSTFVLPQQLDSPHLGEAYQNTNVVDNGEVEGGNSSQQQGAANNTVMPQWMLRHLNG
What is the function of this protein?
Probable transcription factor.
What are the official names of this protein?
Agamous-like MADS-box protein AGL8 homolog, POTM1-1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNH2_MYCA9
Sequence: MSTSWPPRTVIRKASGLRTLELTLDRVGLGPVAGVDEAGRGACAGPLVIAACVLGSNQRKSLAALNDSKKLTEKMRETLFPLICRYAEAYHVVSVPADEVDRIGVHVANIEGMRRAVAGLGVKPGYVLTDGFRVPGLPVPSLPVIGGDASAACIAAASVLAKVSRDRVMVNMDSDHPGYGFAVHKGYSTAVHTEALRRLGPSAQHRQSFVNVRNAAMGSSLMRPLAPRESDTGG
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_TOLAT
Sequence: MIEKLWYQRSWLNWLFAPFAALFALLTTMRRYAYRAGIFSSYRAPVPVIVVGNITVGGNGKTPMVLWLVELLTKAGYKPGVVSRGYGGKAPHYPYLLHPETTAAEAGDEPVLIYQRCGCPVAVAPKRAKAVQLLVEQCGVDVIICDDGLQHYALQRDIEFVVMDGERRLGNGWLMPMGPLRETASRLRQVMAVVCNGGQARPDEIQMSLQPAPLRNVRTNHTAVVSGAVDAMAGIGYPPRFFNSLLKQGYAVNQQVAYADHQAFNAAELHQRFAQRPLIMTEKDAVKCRDFALDNWWYLPVTAQLPEKFATRLLAQLKELRHGAGL
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: PURQ_CHLP8
Sequence: MADLNVGVVVFPGSNCDHDTEYAVASFSGVKPVMLWHNEHDLKGCDAIILPGGFSYGDYLRCGSIARFSPIMREVIDFAGQGRPVLGICNGFQVLVESGLLEGALIRNAGRKFICRQSTISVVNNSTIFTDRYEKGEVLRVPVAHGEGNYYASVETIDSLESNGQVVFRYTDAEGNATAEANFNGSLNNIAGITNKQGNVLGLMPHPERASEELLGSGDGRRVFESLFAHLAGTKRSSRGCCSTSPTRRSAS
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_BURA4
Sequence: MNIYAVGGAIRDELLGVPVQDRDYVVVGATPEQMVAQGFRPVGKDFPVFLHPDTQEEYALARTERKTAAGYHGFQFYFAPDVTLDEDLARRDLTINAMAREVSPEGALVGPVIDPFDGQADLRARVFRHVGDAFVEDPVRILRIARFAARFADFTVADDTLALMRRMVDAGEADALVAERVWQEIARGLMEAKPSRMFAVLRECGALARVLPEVDALWGVPQRADYHPEVDTGVHVMMVVDYAAKQGYSLPVRFAALTHDLGKATTPADVLPRHVGHEGRSVELIKPLCERLRVPNDCRDLALVVAREHGNLHRVMEMGAAALVRFFERSDALRKPARFAEMLQACESDARGRLGLDTQPYPQAERLRVALVAARSVDAGAIARGVGDDVMQIKDAVHRARVEAVKQALAIGE
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: YBB2_YEAST
Sequence: MRSRNKDHRSLLRYLETAPASDFSKEAVEDVVQQPCGDGVKYLLGSARLLVDVCLISRRLDAFGLDGTVIRSFLCALGRGKFLREFWCRHFFLPRCKRPCALFTIYLIPGFLHLIHSVMNYKPLLTSIFPNHK
What are the official names of this protein?
Putative uncharacterized protein YBL012C.
Protein: NADK_IDILO
Sequence: MSAFTKIGLLGKADDRGTQLTLETITTALIHRGFALCLEARTAEQLNLPEEVETLSLPDLGEWAEIAIVVGGDGNMLGAARALCEYDIGVIGVNRGNLGFLTDLDPDEVMTPLLSVLNGNYHVEERFLLSAEVINNGSSSGTGRAINEIVLHSDKVAHMIEFELYVNDHFVFSQRSDGLICATPTGSTAYSLSGGGPILHPGLDAMTLVTMFPHTLSSRPIVVDGNSEVRLKAAFDNDLLQISCDGHVRMTVHPGDDVIIKKYPKALRMIHPIDHNYYHVLRNKLGWGSRLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT25_ASPNC
Sequence: MGKYNLTALRVRQIAVAQQSAGKLRQTPKWLDIMHDVPPTEVLVRNRPQQHQLVRQRLKTVPGASRPQAVFEVQEKRIKPKKASRMFQPVEIKYEEDQLRKEFFRDHPWELARPRVLVEKSGKDFERYNWSRLQQRGKHLDGESVVQRQLWLLNNVPDMTKSAAYDIARREFYRLRLQEDIERRVAAEEAEATGAVFGPTRLQIGMDLENKEYERWKEWAKLQAQLSDQRMAAFLGAPEVQAAEEQETSLDDDATEKVAVAA
What are the official names of this protein?
37S ribosomal protein S25, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the mitochondrion-specific ribosomal protein mS23 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PXG1_ARATH
Sequence: MGSKTEMMERDAMATVAPYAPVTYHRRARVDLDDRLPKPYMPRALQAPDREHPYGTPGHKNYGLSVLQQHVSFFDIDDNGIIYPWETYSGLRMLGFNIIGSLIIAAVINLTLSYATLPGWLPSPFFPIYIHNIHKSKHGSDSKTYDNEGRFMPVNLELIFSKYAKTLPDKLSLGELWEMTEGNRDAWDIFGWIAGKIEWGLLYLLARDEEGFLSKEAIRRCFDGSLFEYCAKIYAGISEDKTAYY
What is the function of this protein?
Calcium-binding peroxygenase involved in the degradation of storage lipid in oil bodies.  May be involved in the interaction between oil bodies and vacuoles during seed germination and in the oxylipin signaling pathways and plant defense responses.  Can catalyze sulfoxidation of thiobenzamide, hydroxylation of aniline, epoxidation of oleic acid or intramolecular oxygen transfer.
What are the official names of this protein?
Peroxygenase 1, AtPXG1, Caleosin-1, Embryo-specific protein 1 (ATS1).
What is the protein family that this protein belongs to?
Belongs to the caleosin family.
What are the subcellular locations of this protein?
Microsome membrane. Lipid droplet.
Protein: PSB2_SCHPO
Sequence: MMGINERKGFDFEYYQRNLLLQEKGFPTPKATSTGTTIVGVIAKDCIVLGADTRATAGPIIADKNCKKLHLISPNIWCAGAGTAADTEFVTSMISSNIELHSLYTNRKPRVVTALTMLKQHLFRYQGHIGAYLVLGGYDCKGPHLFTIAAHGSSDKLPYVALGSGSLAAISVLETKYQPDLERHEAMELVKEAIEAGIFNDLGSGSNCDLVVIDEEKATPYRGYSKPNERATKQSKYTYDRGTTAVLKEDIYKFVTVQDLDEMQVDV
What is the function of this protein?
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity (Potential).
What are the official names of this protein?
Probable proteasome subunit beta type-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.