PharMolix/UniProtQA huggingface dataset:
Protein: POL_SRV1
Sequence: MGQELSQHERYVEQLKQALKTRGVKVKYADLLKFFDFVKDTCPWFPQEGTIDIKRWRRVGDCFQDYYNTFGPEKVPVTAFSYWNLIKELIDKKEVNPQVMAAVAQTEEILKTSSHTELTTKPSQNPDLDLISLDSDDEGAKGSSLKDKNLSCTKKPKRFPVLLTAQTSADPEDPNPSEVDWDGLEDEAAKYHNPDWPPFLTRPPPYNKATPSAPTVMAVVNPKEELKEKIAQLEEQIKLEELHQALISKLQKLKTGNETVTSPETAGGFSRTPHWPGQHIPKGKCCASREKEEQTPKDIFPVTETVDGQGQAWRHHNGFDFTVIKELKTAASQYGATAPYTLAIVESVADNWLTPTDWNTLVRAVLSGGDHLLWKSEFFENCRETAKRNQQAGNGWDFDMLTGSGNYSSTDAQMQYDPGLFAQIQAAATKAWRKLPVKGDPGASLTGVKQGPDEPFADFVHRLITTAGRIFGSAEAGVDYVKQLAYENANPACQAAIRPYRKKTDLTGYIRLCSDIGPSYQQGLAMAAAFSGQTVKDFLNNKNKEKGGCCFKCGRKGHFAKNCHEHIHNNSETKAPGLCPRCKRGKHWANECKSKTDSQGNPLPPHQGNRTEGPAPGPETSLWGGQLCSSQQKQPISKLTRATPGSAGLDLSSTSHTVLTPEMGPQALSTGIYGPLPPNTFGLILGRSSITIKGLQVYPGVIDNDYTGEIKIMAKAVNNIVTVPQGNRIAQLILLPLIETDNKVQQPYRGQGSFGSSDIYWVQPITCQKPSLTLWLDDKMFTGLIDTGADVTIIKLEDWPPNWPITDTLTNLRGIGQSNNPKQSSKYLTWRDKENNSGLIKPFVIPNLPVNLWGRDLLSQMKIMMCSPSDIVTAQMLAQGYSPGKGLGKNENGILHPIPNQGQFDKKGFGNFLTAAIDMLAPQQCAEPITWKSDEPVWVDQWPLTSEKLAAAQQLVQEQLEAGHITESNSPWNTPIFVIKKKSGKWRLLQDLRAVNATMVLMGALQPGLPSPVAIPQGYLKIIIDLKDCFFSIPLHPSDQKRFAFSLPSTNFKEPMQRFQWKVLPQRMANSPTLCQKYVATAIHKVRHAWKQMYIIHYMDDILIAGKDGQQVLQCFDQLKQELTIAGLHIAPEKIQLQDPYTYLGFELNGPKITNQKAVIRKDKLQTLNDFQKLLGDINWLRPYLKLTTADLKPLFDTLKGDSNPNSHRSLSKEALALLDKVETAIAEQFVTHINYSLPLMFLIFNTALTPTGLFWQNNPIMWVHLPASPKKVLLPYYDAIADLIILGRDHSKKYFGIEPSVIIQPYSKSQIDWLMQNTEMWPIACASYVGILDNHYPPNKLIQFCKLHAFIFPQIISKTPLNNALLVFTDGSSTGMAAYTLADTTIKFQTNLNSAQLVELQALIAVLSAFPNQPLNIYTDSAYLAHSIPLLETVAQIKHISETAKLFLQCQQLIYNRSIPFYIGHVRAHSGLPGPIAHGNQKADLATKTVASNINTNLESAQNAHTLHHLNAQTLKLMFNIPREQARQIVRQCPICATYLPVPHLGVNPRGLLPNMIWQMDVTHYSEFGNLKYIHVSIDTFSGFLLATLQTGETTKHVITHLLHCFSIIGLPKQIKTDNGPGYTSKNFQEFCSTLQIKHVTGIPYNPQGQGIVERAHLSLKTTIEKIKKGEWYPTKGTPRNILNHALFILNFLNLDDQNHSAADRFWHSNPRKQFAMVKWKDPLDNTWPWPDPVIIWGRGSVCVYSQTHDAARWLPERLVKQIPNNNQSRE
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.
What are the official names of this protein?
Gag-Pro-Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p10]: Virion. SUBCELLULAR LOCATION: [Capsid protein p27]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein-dUTPase]: Virion. SUBCELLULAR LOCATION: [Protease 13 kDa]: Virion. SUBCELLULAR LOCATION: [Protease 17 kDa]: Virion.
Protein: NG4_DROME
Sequence: MEWKLLLIVLPWLLVCKIFYKVEDFTEPDVAYQSIDYHPEDYIDSFTDFQKHDYFQY
What are the official names of this protein?
Protein new-glue 4, NG-4.
What are the subcellular locations of this protein?
Secreted.
Protein: UVRA_STRP8
Sequence: MQNKIIIHGARAHNLKNIDVEIPRDKLVIVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGTPYCINGHGAITASSAEQIVEQVLALPERTRMQILAPIVRRKKGQHKTIFEKIQKDGYVRVRVDGDIFDVTEVPELSKSKMHNIEVVIDRLVNKDGIRSRLFDSVEAALRLGDGYLMIDTMDGNELLFSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGIKLEVDLDLVVPDPSKSLKEGALAPWNPISSNYYPTMLEQAMASFGVDMDTPFEALTEEERDLVLYGSGDREFHFHYVNDFGGERNIDIPFEGVVTNVNRRYHETNSDYTRNVMRGYMNELTCATCHGYRLNDQALCVHVGGEEGPHIGQISELSIADHLQLLEELELTENESTIAKPIVKEIHDRLTFLNNVGLNYLTLSRAAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIESLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGAGEFGGEIIASGTPKQVAKNKKSITGQYLSGKKFIPVPLERRSGNGRFIEIKGAAQNNLQSLDVRFPLGKFIAVTGVSGSGKSTLVNSILKKAVAQKLNRNADKPGKYHSISGIEHIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGRRYNSETLEVHYKEKNIAEVLDMTVDDALVFFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYILDEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQIVATGTPEEVAQVKESYTGHYLKVKLQQ
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYT_GLAP5
Sequence: MPIITLPDGSQRQFDNPVSVMEVAQSIGAGLAKATIAGRVNGERRDASDIISEDATLEIITAKDEDGLEIIRHSTAHLLGHAIKQLFPNVKMAIGPTIDNGFYYDIDLDRSLTQEDLDALEARMLELAKTNYDVVKKRVSWQEARDTFESRGESYKMAILDENISKDDRPALYHHEEYIDMCRGPHVPNMRFCHHFKLQKVAGAYWRGDSKNKMLQRIYGTAWADKKQLADYLHRLEEAAKRDHRKIGKALDLYHMQEEAPGMVFWHNDGWTIFRELETFVRTKLKQYDYQEVKGPFMMDRVLWEKTGHWQNYGDLMFTTQSENREYAIKPMNCPGHIQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCMPEQVESEVTSCIKMVYDIYSTFGFENIQVKLSTRPANSIGTDEMWNKAEADLAAALTANGLAFEIQEGEGAFYGPKIEFALRDCLDREWQCGTIQLDFFLPERLSASYVAEDNDRKTPVMIHRAILGSIERFIGIITEEYAGFFPAWLAPVQAVVMNITDSQAEYVQQVVKQLSDAGLRVKADLRNEKVGFKVREHTLRRVPYMLVCGDKEIAEGKVSVRTRKGADLGTYKVEEFVEMLKKQVRGRELKLLGEE
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL143_PLAVT
Sequence: MRHCAFLFRLFLIGYSCSVYFSACTQASSLKEPADELPRAEQWDSDGKRILQADDPEHIPTEERGITQNLSPAVESVGKVKASKMAVPKSVISKLNPVNWVKGTWAALKKGFKALQLG
What is the function of this protein?
Secreted effector that completely suppresses the host cell death induced by cell death-inducing proteins.
What are the official names of this protein?
Secreted RxLR effector protein 143.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host cell membrane.
Protein: DDAH1_BOVIN
Sequence: MASLGHPATFGRATHVVVRALPESLAQQALRRTKGDEVDFARAERQHQLYVGVLGSKLGLQVVQLPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEADMMKEALEKLQLNIVEMKDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVVDALHLKSFCSMAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDTAANCIYLNIPSKGHVLLHRTPEEYPESAKVYEKLKDHMLIPVSNSELEKVDGLLTCSSVLINKKVDS
What is the function of this protein?
Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS.  Has therefore a role in the regulation of nitric oxide generation.
What are the official names of this protein?
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, DDAH-1, Dimethylarginine dimethylaminohydrolase 1, DDAHI, Dimethylargininase-1.
What is the protein family that this protein belongs to?
Belongs to the DDAH family.
Protein: RS7_STRGG
Sequence: MPRKGPAPKRPVIIDPVYSSPLVTSLINKILLDGKRSTAERIVYGAMEGLREKTGNDPVITLKRALENVKPSLEVKSRRVGGATYQVPIEVKPGRASTLALRWLVGYSRARREKTMTERLMNELLDASNGLGASVKKREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: DXS_BRASB
Sequence: MTTFSKTPLLDTIKTPEDLRRLKVEQVRQVADELRQETIDAVSVTGGHFGAGLGVVELTTAIHYVFDTPRDRLIWDVGHQAYPHKILTGRRDRIRTLRTGGGLSGFTKRTESDYDPFGAAHSSTSISAGLGMAVARDLSGGKNNVIAVIGDGAMSAGMAYEAMNNAGAMNSRLIVILNDNDMSIAPPVGAMSAYLSRLYSGKTYRTLRDAAKQLGQHLPKVIANRASRVEEYSRGFMMDGGTLFEELGFYYVGPIDGHNLDHLLPVLKNVRDMETGPILVHVVTQKGKGYPPAEASADKYHAVVKFDVATGTQAKAKPNAPAYQNVFGQSLVKEAEKDDKVVGITAAMPSGTGIDIFAKAFPKRTFDVGIAEQHAVTFAAGLAAEGFKPFCAIYSTFLQRGYDQIVHDVCIQSLPVRFAIDRAGLVGADGATHAGSFDNAYLGCLPNMVIMAASDEAELVHMVATQVAINDRPSSVRYPRGEGRGVEMPEVGVPLPIGKGRMIRQGKQVALLSFGTRLAECEKAADELAAHGLSASIADARFMKPLDEELVLKLAREHEILITIEEGSIGGFGSHVMQYLADQGMLDGGLKMRSMVLPDEFQDHDTPAAMYARAGLDAKGIVRKVFEALGKDYTAEVVKLA
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: RS18_PSEA7
Sequence: MARFFRRRKFCRFTAEGVKEIDYKDLNTLKAYVSETGKIVPSRITGTKAKYQRQLATAIKRARYLALLPYTDSHGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PKNL_MYCTU
Sequence: MVEAGTRDPLESALLDSRYLVQAKIASGGTSTVYRGLDVRLDRPVALKVMDSRYAGDEQFLTRFRLEARAVARLNNRALVAVYDQGKDGRHPFLVMELIEGGTLRELLIERGPMPPHAVVAVLRPVLGGLAAAHRAGLVHRDVKPENILISDDGDVKLADFGLVRAVAAASITSTGVILGTAAYLSPEQVRDGNADPRSDVYSVGVLVYELLTGHTPFTGDSALSIAYQRLDADVPRASAVIDGVPPQFDELVACATARNPADRYADAIAMGADLEAIAEELALPEFRVPAPRNSAQHRSAALYRSRITQQGQLGAKPVHHPTRQLTRQPGDCSEPASGSEPEHEPITGQFAGIAIEEFIWARQHARRMVLVWVSVVLAITGLVASAAWTIGSNLSGLL
What is the function of this protein?
Phosphorylates the DNA-binding protein Rv2175c.  May be involved in the regulation of cell division and cell envelope biosynthesis.
What are the official names of this protein?
Serine/threonine-protein kinase PknL.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: GUAA_PSEP1
Sequence: MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFNPRGIILAGGPESVHEANSPRAPQAVFDLNVPVLGICYGMQTMAEQMGGKVEGSDLREFGYARVDVVGKSRLLDGIEDHVDDDGVLGLDVWMSHGDKVTQMPGNFNILASTPSCPIAGMYDDVRGYYGVQFHPEVTHTKQGGRILSRFVQDICGCEALWTASNIVEDAIAQVRAQVGSANVLLGLSGGVDSSVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMAMFKENMGVKVIRADAEKQFLDNLAGEADPEKKRKIIGRTFIDVFDAEASKLENIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDFMTARWAHLPYELLETVSGRIINEIDGISRVTYDVSSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RS8_METB6
Sequence: MTRLNTIADGMSALKNAGDTGKSEVTIEPASKLLGAMLRIMQDAGYIAGFEFIEDGRGGQLKVHLTGKINKCGAICPRFSVQLDEMEYWEKQYLPGKNFGLMILSTSHGVMSHVQARREGIGGELLGYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: MENC_ECOK1
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEDAQSVLLAWVNNWLAGDCEIPQMPSVAFGVSCALAELAETLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLDKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSPLPLVDVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: HBB_AOTAZ
Sequence: MVHLTGEEKAAVTALWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSPDAVMNNPKVKAHGKKVLGAFSDGLAHLDNLKGTFAQLSELHCDKLHVXPENFRLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YWBI_BACSU
Sequence: MDIRHLTYFLEVARLKSFTKASQSLYVSQPTISKMIKNLEEELGIELFYRNGRQVELTDAGHSMYVQAQEIIKSFQNLTSELNDIMEVKKGHVRIGLPPMIGSGFFPRVLGDFRENYPNVTFQLVEDGSIKVQEGVGDGSLDIGVVVLPANEDIFHSFTIVKETLMLVVHPSHRLADEKECQLRELKDEPFIFFREDFVLHNRIMTECIKAGFRPHIIYETSQWDFISEMVSANLGIGLLPERICRGLDPEKVKVIPLVDPVIPWHLAIIWRKDRYLSFAARAWLEHTKSYLWDPKKDSKG
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YwbI.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: PELO_PYRAB
Sequence: MEVLEEKPKEGKVKLKVETLDDLWHLYHVISPGDIVYAKTLRKQAQRSDSLRPEKVEAIPVFLGVRAEKINLHRFANQLRVTGPIVYASRDDVPLGKYHTIAVEPGMTITIQKERWRSHHVERIKEAVEASKRAKVMIVAMEDGEAEVAIVREYGLDFIASIRHNIGGKRYNVKREDEEKKFFHDVAKTIKDLIERENVQKVIVAGPGFYKENFYGFLRENYPELAGKVVLDDTSMGGRVGVYEVIKRGTVDKVYTETRVAQEIKLVEKVIERIAKDEPVAYGLKDVEEAVNYGAVDTLLVLDELLKGDDRERIEEIMEMARNLRANVVVVSSEHEGGDKLKALGGIAAILRFKIH
What is the function of this protein?
May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA.  May play a role in the release non-functional ribosomes and degradation of damaged mRNAs.  Has endoribonuclease activity.
What are the official names of this protein?
Protein pelota homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_CHLAB
Sequence: MKTFKGIASAKDMRVAIVGSCFNGPIADALVSGAAQTFLELGGAEDRLTIVRVPGAFEIPCTLKKLLTSGIEYHAIVACGVLIKGETTHYDHIADQVSARISELSVEYNLPITFSIITAPCVDSAWQRAGIKGSHLGVSGMRTALEMADLFKKL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: MTFA_ESCF3
Sequence: MIKWPWKAQETPQQDNPPWEDALAIPILHSLTTEEQTRLVALAERFLQQKRIVPLQGFELDSLKSARIALLFCLPVLELGIEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWVDIRDSFDASGFNLIIHEVAHKLDMRNGDRASGIPLIPLREVAGWEHDLHAAMENIQEEIDLVGETASSIDAYAATDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQFYGQNPLLRLRNSPNNDASPTTNVH
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPRT_ASFK5
Sequence: MLHLIYISIIVVLIIILISYTRKPQYFRITAPRSVALFHGIHPLNPKNYKTFSEEFETILNNAIEDGDFKGQLTEPCSYALRGGKYIRPIILMEIVRACQLQHSFGAPIYPAEAALAVEYFHVASLIIDDMPSFDNDVKRRNKDTVWARFGVAKAQMSALALTMQGFQNICRQVDWIKENCPRFPDPNQLGALLCTFVSHSLNSAGSGQLVDTPEKTIPFFKIAFIMGWVLGTGTIEDIGAIERAAHCFGNAFQLADDIKDHDTDTGRNYAKIHGKRKTFDVVAQSLQECKKILHEKKIYTSIWNEIFQKVINVALGT
What is the function of this protein?
Trans-prenyltransferase that catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with different allylic diphosphates, such as dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP), farnesyl diphosphate being the best allylic substrate.
What are the official names of this protein?
Trans-prenyltransferase, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyltranstransferase, Geranyltranstransferase, Polyprenyl-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family. Asfivirus trans-prenyltransferase subfamily.
What are the subcellular locations of this protein?
Host endoplasmic reticulum. Host membrane; Single-pass membrane protein.
Protein: TTPA_RAT
Sequence: MAEMRPGPVVGKQLNEQPDHSPLVQPGLAELRRRAQEEGVPETPQPLTDAFLLRFLRARDFDLDLAWRLMKNYYKWRAECPELSADLHPRSILGLLKAGYHGVLRSRDPTGSRVLIYRISYWDPKVFTAYDVFRVSLITSELIVQEVETQRNGVKAIFDLEGWQISHAFQITPSVAKKIAAVVTDSFPLKVRGIHLINEPVIFHAVFSMIKPFLTEKIKGRIHLHGNNYKSSLLQHFPDILPLEYGGNESSMEDICQEWTNFIMKSEDYLSSISETIQ
What is the function of this protein?
Binds alpha-tocopherol, enhances its transfer between separate membranes, and stimulates its release from liver cells.  Binds both phosphatidylinositol 3,4-bisphosphate and phosphatidylinositolphosphatidylinol 4,5-bisphosphate; the resulting conformation change is important for the release of the bound alpha-tocopherol (By similarity).
What are the official names of this protein?
Alpha-tocopherol transfer protein, Alpha-TTP.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1614_HUMAN
Sequence: MEGTEAAAAKPAGGSPQGPKTGSGTASPVEGTSAVEWSGPEPQLDNGHPPRPWPCPQENRTSSLMAPQPPRVWGVQLQGPSVLESKVRALKEKMTVAKQGVSPCSASQEWSSPKKPQCRRGKAGRAGTPSEGSFLPGAVVAPRTQNLPDGQLDGSINEEQPARDGGPRLPRPPAPGREYCNRGSPWPPEAEWTLPDHDRGPLLGPSSLQQSPIHGVTPGRPGGPGHCNKIIHIPSPRTGRSYPFPDGVVTEADLDSTSLTSEEVFVPRTALLGERWRAGDLEALGAGSSVLSLSDRVERNRLLLQEMLNVSGQSPRKVGTPAWTPSWDTAAPERPVGDVDWASGTSLQDSGQNRTVGPNPEPVLSPRHEEATHLLQRARMKARTRPLRASHDIVPTITQGSRDGHRSPARDPRTTPACRDSLQNGHTSDSSSGESSGGHRPRRGPSPSHVRFEDESAREAEFRHLERLQQRQRQVLSTVLQAADQGPLRSKPDLADYINGAPRLRDAGQGTFHRLVGSLDRRGHPAPPAPGSERRCQACGSCIDDPRPAQGKAPPVPRTLQELQAACGMERVLGGLSSPLRLLPAEPRLHMEWIRETHIGDTVCPAEVDSALDSTDNSDNCRTDSEEAGTSQAGWACGRTQGSSPRLRLRGSRPRGHRWSKKAEAELPWGLQAQQHLPRADDVEVENEVKEGRGHTPEGTLFLREDAKPPDLELKRVSLGPQWQPGPGLGSHQPHPLDSRTPCRTAYATTAPMTPESSGPGGQAQVTESHESLEIVSPSSLQQSHAEPSAPHQAWQPTASLCPEGWAPTPPPSRKTTSPVSHRKAALAGLLRLGDQTEPVGIPRPPSRSAVLRTCELPPSQTQPSRPQVRHPLLALSTNNCNNSAPRGLQEPYGGAVHEGRVERGPCSREPEPPLENSRDGGPQGFLGSADVATINSTGITLSLSSEESESSKESEGSLQRTGSGSGGHVLSRASAGAGTGPGSPSAAPLDQNKKRSSSIASTLGLKKLFSALGQSSRPKLGKSRSYSVEQLQPAPPGLTSQSRAPSLQSLHPVSPSHQRRKAASFQNLHSLLSSKGNRSSLYLVAGPGDHSAAGRPAKTSPRRALSVEDVGAPSLARTVGRLVEVFPDGTSQLQLQRSPGGTFGFCVASGNGRPDSGMPSPLPQPHGWGGLSKQGRAFWLWSEAFLVFG
What are the official names of this protein?
Uncharacterized protein KIAA1614.
Protein: SSN8_YARLI
Sequence: MSANYWTSSQRLHWLLTKETLAERRKGLEDIFDPGKLQTIKALNPWHVRVYLHTLIHLLGQNLSIRQRILATAEVYLTRFHTKVPFGEINPYLVVATAVYVACKVEEHPQHIRTITSEARSLWPDYISHDPTKIAECEFYLIEELGTYLVIFHPYKSLMQISDAMARSNAQITMAPEEIQVTWSMINDSYITDLHLLNPPHIVAMACIYMTVVLRSHIMRMTMPSEAVKSRIEAFMTFFGESNVDLEQTIDCVQEMISLYVNWDTYSEKQCRVEIAKVIT
What is the function of this protein?
Component of the SRB8-11 complex.  The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription.  The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator.  It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.  The SRB8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By similarity).
What are the official names of this protein?
RNA polymerase II holoenzyme cyclin-like subunit.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin C subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TADA3_DANRE
Sequence: MSELKDCPPLKYYDFKPVDHVKVCPRYTAVLSRSEDDGIGIEELDTLQLELETLLSSASRRLRALEEQRQILTDWQDKKGDKRFLKLEKDPDLAASSRHSKPKKQKLDVKGSHGPGPGPGRPKSKNIQTKVQDFEFEVDPQDIPRNPKNDAPNRFWASVEPYCADITNEEIRVLEELLKAPDDEAEYYKIPTLGKHYSQRWAQEDLLEERREGARANDKKKSMMGPLSELDAKDVDALLKKSESQHEPPEDGCPFGPLSQRLLQALVEENIISPMEDSPIPDIPGKDDGAGTSPRSQGKAFSVPHTRSLEARIREELVSQGLLDSDERQGVGGESEDEVLAELQKRQAELKALTAHNRSRKLELLKLAREEMRKQELRQRVRVADNEVMEAFRRIMAARQKKRTPTKKEKDQAWKALKERESILKLLDG
What is the function of this protein?
Functions as a component of the PCAF complex.  The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context (By similarity).
What are the official names of this protein?
Transcriptional adapter 3, ADA3 homolog, Transcriptional adapter 3-like, ADA3-like protein.
What is the protein family that this protein belongs to?
Belongs to the NGG1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS7_HORVU
Sequence: MYTARKKIQKDKGVEPSEFEDTVAQAFFDLENGNQELKSDLKDLYINTAIQMDVVGNRKAVVIHVPYRLRKPFRKIHVRLVRELERVSGKDVVFVATRRIVRPPKKGSAVQRPRTRTLTAVHDGILEDVVYPAEIVGKRVRYRLDGAKVIKIYLDPKERNNTEYKLETFSAVYRRLCGKDVVFEYPVAETA
What are the official names of this protein?
40S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS7 family.
Protein: METXA_NAUPA
Sequence: MKIETKIAKFTKPLYLESGRILEPWQIIYETYGELNEKKDNVILITHALSGSHHAAGMYEGDRKPGWWDGLIGDGKAIDTTKYFVISTNVIGSCFGSTSPMSPIHPGSSERYRLKFPVVTIKDMVKAQKILLDSLGIRHLKAIVGGSMGGMQALRFAVDFPGFCENIIPIATTYQTKPYVIAINKSMIEAIRADSEFKNGNYDPDIIKQNGLKGLAAARMIGYLNYISPKTFERKFGREYVKTDGMFELFGRFQVESYLEYNGAMFPKWFDPLSYIYILKAISLFDISRGFVSLEDAFSQIKDKLHLISFSGDTLFFPEEMRDIKNYMDKVGGKCNYFEINSDYGHDSFLVELEKFDFIISDILKGEV
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_LSV
Sequence: ARERMDEEELEAFYNCVRIIVKNKHLLKSDVRNVYEEQLD
What is the function of this protein?
RNA replication.  The central part of this protein possibly functions as an ATP-binding helicase.
What are the official names of this protein?
RNA replication protein, ORF 1 protein.
What is the protein family that this protein belongs to?
Belongs to the potexviruses/carlaviruses RNA replication protein family.
Protein: GSPD_AERHY
Sequence: MINKGKGWRLATVAAALMMAGSAWATEYSASFKNADIEEFINTVGKNLSKTIIIEPSVRGKINVRSYDLLNEEQYYQFFLSVLDVYGFAVVPMDNGVLKVVRSKDAKTSAIPVVDETNPGIGDEMVTRVVPVRNVSVRELAPLLRQLNDNAGGGNVVHYDPSNVLLITGRAAVVNRLVEVVRRVDKAGDQEVDIIKLKYASAGEMVRLVTNLNKDGNSQGGNTSLLLAPKVVADERTNSVVVSGEPKARARIIQMVRQLDRDLQSQGNTRVFYLKYGKAKDMVEVLKGVSSSIEADKKGGGTATTAGGGASIGGGKLAISADETTNALVITAQPDVMAELEQVVAKLDIRRAQVLVEAIIVEIADGDGLNLGVQWANTNGGGTQFTNAGPGIGSVAIAAKDYKDNGTTTGLAKLAENFNGMAAGFYQGNWAMLVTALSTNTKSDILSTPSIVTMDNKEASFNVGQEVPVQTGTQNSTSGDTTFSTIERKTVGTKLVVTPQINEGDSVLLTIEQEVSSVGKQATGTDGLGPTFDTRTVKNAVLVKSGETVVLGGLMDEQTKEEVSKVPLLGDIPVLGYLFRSTSNNTSKRNLMVFIRPTILRDANVYSGISSNKYTLFRAQQLDAVAQEGYATSPDRQVLPEYGQDVTMSPEAQKQIELMKTHQQATADGVQPFVQGNK
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity).  This subunit forms the outer membrane channel (By similarity).
What are the official names of this protein?
Secretin ExeD, General secretion pathway protein D, Type II secretion system protein D, T2SS protein D.
What is the protein family that this protein belongs to?
Belongs to the bacterial secretin family. GSP D subfamily.
What are the subcellular locations of this protein?
Cell outer membrane. Note=Most of the protein is in the periplasm which it traverses to contact proteins of the cell inner membrane.