PharMolix/UniProtQA huggingface dataset:
Protein: TIM50_YEAST
Sequence: MLSILRNSVRLNSRALRVVPSAANTLTSVQASRRLLTSYSSFLQKETKDDKPKSILTDDMLFKAGVDVDEKGQGKNEETSGEGGEDKNEPSSKSEKSRRKRQTSTDIKREKYANWFYIFSLSALTGTAIYMARDWEPQESEELKKDIDNGYTLSLMYKRFKARFNSMFTYFQEPPFPDLLPPPPPPPYQRPLTLVITLEDFLVHSEWSQKHGWRTAKRPGADYFLGYLSQYYEIVLFSSNYMMYSDKIAEKLDPIHAFVSYNLFKEHCVYKDGVHIKDLSKLNRDLSKVIIIDTDPNSYKLQPENAIPMEPWNGEADDKLVRLIPFLEYLATQQTKDVRPILNSFEDKKNLAEEFDHRVKKLKDKFYGDHKSGGNWAMTALGLGNSLGGSTKFPLDLIHEEGQKNYLMFMKMIEEEKEKIRIQQEQMGGQTFTLKDYVEGNLPSPEEQMKIQLEKQKEVDALFEEEKKKKKIAESK
What is the function of this protein?
Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.  Required to direct preproteins in transit and direct them to the channel protein TIM23, and possibly facilitates transfer of the translocating proteins from the TOM complex to the TIM23 complex.  Does not act as a structural subunit of the TIM23 complex but plays a dynamic role in protein import.  Has no phosphatase activity.
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM50.
What is the protein family that this protein belongs to?
Belongs to the TIM50 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PYRB_BUCAT
Sequence: MRNSLYKKNIISINDLQRNELELVLNKSAMLKRTPQPNLLKNKVIASCFFEASTRTRLSFETAIYRLGASIVGFSDGNNISLEKKGETLTDTISVISSYVDAIIIRHPQEGSARLAAEFSNKKPIFNAGDGANQHPTQTLLDLFTIQETQNRLTQLNIAIVGDLKYGRTVHSLTQALAKFKHNKFYFISPDALKMPNYINNMLDKKEIYWKRHNNIEEIISEIDILYMTRIQKERLDSTEYANAKSKFVLRAAILKNARNNMKILHPLPRIDEIDRDVDYTPYAWYFKQAANGIYARQAILSLVLIEKHL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: LIPLB_PLAF7
Sequence: MRIIKCLDQIFRPVLPNVNINNIQKNKKINILYFIDVSKFHVFEQLLLEESLFRISNNTTEGLNNIGFVIVNNTCEEMNESKGNECIFNNKKCVILGISNKIKDHIKDTNYIKENKISLIKRFTGGGTIYINKNSLLVSLILPHKFEKNKKIYPSNITEWSYNYFYNTSKQIYDKTQINNEKNSLNKNHILFNQYFNYYENDYVYKDYDEHNKNIILKKVGGNAQSFARNYFVHHTSYIWTCDYKEMNNILLNPSKQPIYRNKRKHQHFLQSIKLCLHDDIHTPNIFIEKLIKHIKHIINYKNITDQHDYWFFNKINLKNINDHILRNSEHFDDIYVADMNLLQCIFNYYNNSSLFNNMRSTYFLDLEGKKVSDRYYDIPTYFL
What is the function of this protein?
In the mitochondrion and together with LipL1, involved in the lipoylation of the E2 component of the branched chain alpha-ketoacid dehydrogenase complex BCKDH-E2/BCDH and the E2 component of the alpha -ketoglutarate dehydrogenase complex KDH (PubMed:25116855).  LipL1 is responsible for catalysing the activation of lipoate, forming lipoyl-AMP while LipL2 is required but is not capable of catalyzing this reaction (PubMed:25116855).  Although its role is unclear, it may catalyze the transfer of lipoyl groups from lipoyl-AMP to BCDH and KDH or act as an effector protein (PubMed:25116855).
What are the official names of this protein?
Inactive lipoate--protein ligase 2.
Protein: KHSE_HALLT
Sequence: MVTVRAPATSANLGSGFDVFGAALTRPADVVTVEKAAETTIEVTGVGAQYIPEDPKKNTVGAVVEALDAPARIHIDKGVRPASGLGSSAASAAGAAVALNRLYDRGLSRSELVPIAAEGEAVVSGVAHSDNVAPSILGGFTVTTSEGTHAVDASIPLVVCLPDVAVSTRDARRVVPETASMDDLVETVGNAATLAIGMCRSDPDLVGAGMSDPVVTPERARLITGYDEVRAAAFDAGATGVTVSGAGPAILAVCRDGQRRGVAAAMLDAFSDAGIDSRAYQTRIGRGSTVLEE
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_KOCRD
Sequence: MAMIIALQARQILDSRGNPTVEVEALLDDGSFGRAAVPSGASTGEFEAVERRDGDKKVYQGKGVLDAVHAVDEELEQVVVGLDASDQRAVDQAMLELDGTDNKAKLGANAILGASMAIARAAASSADLPLYKYLGGPNAHVLPVPMMNILNGGSHADSNVDIQEFMIAPIGAPTFSEALRWGVEVYHSLKSVLKDRGLSTGLGDEGGFAPNLESNAAALDLILEAIDKAGYKPGRDIALALDVASSEFFDKGTYTFEGKKRSAEEMSAYFADLVEKYPLVSIEDPLDEDDWKGWATLTEHIGDKVQLVGDDLFVTNPERLARGIQEGVANALLVKVNQIGSLTETFDAVELAQRNGYRCMISHRSGETEDTTIADIAVAVNAGQIKTGAPARSERVAKYNQLLRIEEELGDAATYAGASAFPRFAAK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PSBC_GUIAB
Sequence: MKTLYSLRRFYPVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFLAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSIIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICILGGIWHILTKPFAWARRALVWSGEAYLSYSLAAISVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFFFVGHLWHAGRARAAAAGFEKGIDRDFEPVLSMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS21_SALSV
Sequence: MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTERKRAKASAVKRHAKKLARENARRTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: PNP_SODGM
Sequence: MLNPIVRKFQYGQHTFTLETGMMARQATAAVMASMDDTAVFVTVVGAKQAKTGQSFFPLTVNYQERTYAAGRFPGGFFRREGRPSEGETLISRLIDRPIRPLFPEGFLNEVHVIATVVSVNPQVSPDIVAMIGASAALSLSGIPFSGPIGAARVGYINDQYVLNPTQAELATSRLDLVVAGTQNAVLMVESEAQLLSEDQMLGAVVYGHDQQQIVIDNINQLVAEAGKPKWQWQAQDVNAGLQARVAELAESRLGDSYRITEKQERYAAVDAIKADVVEALTGQDETLDVGEIKDILGALEKSVVRSRVLRGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTERDAQNIDELTGERTDRFLLHYNFPPYCVGETGMVGSPKRREIGHGRLAKRGVLAVMPNASEFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNFVVLSDILGDEDHLGDMDFKVAGSREGVTALQMDIKIEGITHEIMQVALNQAKGARMHILGVMERAISSPRGNISEFAPRIHTIKISSDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKVAATDGDKARHAIRRIEEITAEIEVGRIYNGKVTRIVDFGAFFAIGGGKEGLVHISQIADKRVEKVADYLELGQEVPVKVLEVDRQGRVRLSIKEASAPSQDAVVPEAE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NHAA_FRATT
Sequence: MGASQKNQELIGGLILFSAALLAIVVNNSPLASYYAMLETINVKLGIENLVIDKNLMHWINDGLMAIYFLYIGLEIKREIIVGTLSKPSNIITPAIAAFAGLAMPSLIYLSINHDIKVINGWAIPSATDIAFTLGILALLGTRVPAKLKLLVITIAIFDDIAAIAIIAIFYTKSLSLLSLSLGTLFILAMIICNRIFKINRSSVYVVLGFFAWFCTIKSGVHATLAGFTTALCIPFRENDKDSPANFMEDSLHPWIIYFILPVFAFANAGISFSGISFSILFEPITLGIIWGLFVGKQLGIFSILAVFKKLKWFKLGESFSNLQLYGISLLCGIGFTMSLFIGVLAFNDTHLLNAIKIGVVVGSVLSGFFGYIVLRFIVTNPS
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TOP3_STAAW
Sequence: MKSLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHLVTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIATDAGREGELVARLILDKVGNKKPIRRLWISSVTKKAIQQGFKNLKDGRQYNDLYYAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYFTLSLTVKGFDFQLESNQRYTNKETLEQMVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQDMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQATMATTYKDQARPLMSKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLEALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKISKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADIIDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAKTFINEMKDFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKVSRKEMKKYMNKNEGLDNNPFKDALKNLNL
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: PG139_VAR67
Sequence: MIGILLLIGICVAVTVAILYAMYNKIKNSQNPSPNVNLPPPETRNTRFVNNLEKDHISSLYNLVKSSV
What is the function of this protein?
Essential for the encapsidation of DNA into immature virions (IV) and the subsequent maturation of IV into mature virions (MV).
What are the official names of this protein?
Virion membrane protein OPG139.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG139 family.
Protein: RF1_NITEU
Sequence: MNKGIIDQLTRLSMRLGELDKLLSTEKITADLDNYRKLSRERAEIEPVTELYRTYQQVEQDLATAREMSSDPQFRDFAEAEIEADRRKLTNIETEILRQLLPKDPNDERNIFLEIRAGTGGDESALFAGDLFRMYSRYAEREGWQVEVVSQNPSEVGGYKEIIVRIIGHGAYSRLKFESGGHRVQRVPATETQGRVHTSTCTVAVLPEADEIADITLNPADLRIDTFRASGAGGQHINKTDSAVRITHLPTGIVAECQEGRSQHKNKAQAMSVLIARILDKQVRAQQAEQAATRKSLVGSGERSERIRTYNFPQGRITDHRINLTLYKIEQIIDGELDELCSALAAEHQAAQLAAMTEK
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCX6_CHLRE
Sequence: MTLALMQSMGKLKFLHCLLPLPFRDVPFPLRASKLRDFNAINKFVPLRDVSGSCEVLILYINIECLHTPKEDVSGSGTATAILILRRSSGGPTATKIYLPEDVLPTAEANEF
What are the official names of this protein?
Uncharacterized 12.3 kDa protein in petA-petD intergenic region, ORF102.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NEP_I67A2
Sequence: MDSNTVSSFQDILMRMSKMQLRSSSEGLNGMVTQFESLKIYRDSLGEAVMRMGDLHYLQNRNEKWREQLGQKFEEIRWLIEEVRHKLKITENSFEQITFMQALQLLLEVEQEMRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RS8_RUMCH
Sequence: MQITDAIADMLTRIRNAGSAKHESVDIPASNLKRSIANILLEEGYIKNFEEISDGKQGVLRVNLKYNNKQNVITGIKRISKPGLRVYAGKDQLPKVLGGLGIAVISTSKGIMTDKKARVEGIGGEVLAFVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: SYR_CLOBA
Sequence: MDYKNKIAQLIKQHVDLDIDAIEKLIEIPPKSEMGDYAFPCFQLSKVMRKAPNMIAETLKDAINKDGFERIENLGPYLNFFVDKGVFAENTINKILKDGDSYGESNIGEGKTVCVEYSSPNIAKPFHVGHLFTTAIGNSLYKMFKKEGYDVVGLNHLGDWGTQFGKLISAYNRWVDEEALEKAPIDELLRIYVKFHDEAEKDPSLEDEGRMYFKKLETGDAEAQALWKRFRDLSLKEFERVYDILGVKFDSLAGEAFYNDKMDVVVNELKDKGLLVESNGAQVVMLDDYNMPPCIVLKGDGASIYATRDLAAAMYRKKTYDFYKSIYVVGSPQALHFKQVFKVLELAGHEWANDCVHVGFGLVKFADRKLSTRKGEVVLLDDLIRESVEKTLEVINEKNPELENKEEVAKKIGVGAIIFTYLKNSREKDIVFDWKEILSFEGETGPYVQYSYARANSIISRAENISSEVDYSKLSSKEEFELVKVLANFNNQIKLATDKLEPSILTRYVIDVAKSFNKFYNAHSVLNLDDEVLKATRLSLVKSSLQVIKNGLELLGIDVVEKM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBM_CYCTA
Sequence: MEVNILAFIAIVLFISVPTAFLLIIYVKTVSESN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface.
What are the official names of this protein?
Photosystem II reaction center protein M, PSII-M.
What is the protein family that this protein belongs to?
Belongs to the PsbM family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PSBA_AMPOP
Sequence: MTSLIRSNSWGSFVQTITSSSNRLYIGWFGLLVFPLLSLATVAYITAFFLAPAVDIDGIREPVAGSLIYGNNIISGAVIPSSNAIGVHFYPLWESLGLDEWLYNGGTYQFVVFHFFLGVCGWMGREWEFSYRLGMRPWIFVAFSAPIAAAAAVFIIYPIGQGSFSDGMPLGIQGTFNFMLVFQAEHKILMHPFHILGVAGVFGGSLFSAMHGSLVSSSLLAETAGSESLNNGYVFGQEDETYSISAAHAYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTSLGVATMAFNLNGFNFNQSILDESGHYINSWADILNRADLGIEVMHERNAHNFPLDLA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RBL_APHSI
Sequence: VGFKAGVKEYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVPGETDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYIKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVAVEACVQARNEGRDLAAEGNAIIREASKWSPELAAACEVWKELKFEFQAVDTLD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RUVB_STRSY
Sequence: MTNRILDMEQMQDEEYVERTLRPQKLNEYIGQDKVKDQLKIFIEAAKLRDEALDHTLLFGPPGLGKTTMAFVIANELGVNIKQTSGPVIEKAGDLVALLNDLEPGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGEASRSVHLELPPFTLIGATTRAGMLSNPLRARFGITGHMEYYELADLTEIVERTADIFDMEITHEAAIELARRSRGTPRIANRLLKRVRDFAQIMGDGLIDDSITDKALTMLDVDREGLDYVDQKILRTMIEMYGGGPVGLNTLSVNIAEERETVEDMYEPYLIQQGFLMRTRTGRVATAKAYEHLGYPYTEK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: NU4LC_SOLBU
Sequence: MILEHVLVLSAYLFSIGIYGLITSRNMVRALMCLELILNAVNINFVTFSDFFDNRQLKGDIFSIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSNLLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: APT_METFK
Sequence: MNIKSLIRTIPDYPKPGIQFRDITTLLKDASGLRQVVDALVERYAGAKVDKVVGIESRGFIVGAAVAYELGVGFVPVRKKGKLPGDVLGHDYALEYGTDRVEIHSDAISPDEHVLLLDDLIATGGTAEAAAILIEKLGGHVLECAFIIGLPDLGGERKLRVLGYKTFSLCQFEDSE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURG_HELPH
Sequence: MKFALTGGGTGGHLSIAKALAIELEKQGIEAIYLGSTYGQDKEWFENSPLFSERYFFNTQGVVNKSFFKKIGSLFLQAKAAFKAKEILKKHQITHTISVGGFSAGPASFASLLNKIPLYIHEQNAIKGSLNRYLSPKAKAVFSSYAFKDKGHHVLTSYPVQNAFFDFARTRTEIKHILFLGGSQGAKAINEFALLNAPKLTKQGIKITHICGPNSYEQVRFFYQELGLLDKIELFAFHNNITEVMHRADLCVSRAGASSVWELCANGLPTIFIPYPFASNNHQYYNVLEFEKENLCYVAPQNELLPKKLFEVIRKLNQKDDQGNKNLTAISNQLQQKIAKDGAKTIIETILSA
What is the function of this protein?
Cell wall formation.  Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).
What are the official names of this protein?
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family. MurG subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SPRTL_STAAE
Sequence: MNNDKLQRMVENLSEEKFGRTFRHCAYFNKRLRTTGGRYLLKSHDIEINPKQYEHYGEDAVVKIILHELCHYHLHIAGKGYQHKDQDFKRLSQQVGAPRFCNSIESYQQRANYEYYCTKCHAKYIRIRKVDTNRMRCGHCNGKLRMKRQLK
What are the official names of this protein?
Protein SprT-like.
What is the protein family that this protein belongs to?
Belongs to the SprT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FAO3_ARATH
Sequence: MDKYKVAGKFGLPDITVAEMESLASFCEAVLPSVQPPPEELSGEGDNHRNKEALRSFYSTSGSKTPVLRQSIELVTKRGTIEAYIATRLILFLLATRLGTLLICGTECLVSRWPFVEKFSELSLEKRERVLQKQFKNWILTPIRAAFVYIKVAFLFCFFSRVNPNGENPAWEAIGYRVNPDENKPSETHNERPLEKGIVETMEETEQTLLESLAHKGLEAVLDTEHDAIRIKCDVVVVGSGSGGGVAASVLAKSGLKVVVLEKGSYFTPSEHRPFEGPGLDKLYENGGILPSVDGSFMVLAGATVGGGSAVNWSACIKTPKSVLQEWSEDQNIPLFGTKEYLTAMEVVWKRMGVTEKCELESFQNQILRKGCENLGFNVENVPRNSSESHYCGSCGYGCRQGDKKGSDRTWLVDAVGHGAVILTGCKAERFILEKNGSNKGGKQMKCLGVMAKSLNGNIAKMLKIEAKVTVSAGGALLTPPLMISSGLRNRNIGKNLHLHPVLMAWGYFPDKESSNISFKGNSYEGGIITSVSKVLSEDSEVRAIIETPQLGPGSFSVLTPWTSGLDMKKRMARYSRTASLITIVRDRGSGEVKTEGRINYTVDKTDRDNLKAGLRESLRILIAAGAEEVGTHRSDGQRLICKGVNENSIQEFLDSVSTEEGAKGMTEKWNVYSSAHQMGSCRIGENEKEGAIDLNGESWEAEKLFVCDASALPSAVGVNPMITVMSTAYCISTRIAKSMTTGLSH
What is the function of this protein?
Long-chain fatty alcohol oxidase involved in the omega-oxidation pathway of lipid degradation.
What are the official names of this protein?
Long-chain-alcohol oxidase FAO3, Long-chain fatty alcohol oxidase 3.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
What are the subcellular locations of this protein?
Membrane.