PharMolix/UniProtQA huggingface dataset:
Protein: GLYA_HELPG
Sequence: MAYFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKRYYGGCEVVDKIESLAIERAKKLFNCQFANVQAHSGSQANNAVYHALLKPYDKILGMDLSCGGHLTHGAKVSLTGKHYQSFSYGVNLDGYIDYEEALKIAQSVKPEIIVCGFSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVTNEHAHPFPHCHVVSSTTHKTLRGPRGGIILTNDEEIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLKPEFKAYAKLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAGITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLHVKEELKAMANQFPVYQQPIF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_LACLM
Sequence: MKKVLVKAVHCYQRWISPALPPACRYYPTCSNYMIQAIEKHGPDKGLAMGTARILRCHPFCQPGYDLVPEHFSLRRNWAEPEKKEEEDSK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PYRE_ECOSE
Sequence: MKPYQRQFIEFALGKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGLEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERGRSEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: INSL4_PANTR
Sequence: MASLFWSYLPAIWLLLSQLLRESLAAELRGCGPRFGKHLLSYCPMPEKTFTTTPGGWLLESGRPTEMVSTSNNKDGQTLGTTSEFIPNLSPELKKPLSEGQPSLKKIILSRKKRSGRHRFDPFCCEVICDDGTSVKLCT
What is the function of this protein?
May play an important role in trophoblast development and in the regulation of bone formation.
What are the official names of this protein?
Early placenta insulin-like peptide, EPIL, Insulin-like peptide 4, Placentin.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VE7_HPV05
Sequence: MIGKEVTVQDIILELSEVQPEVLPVDLFCEEELPNEQETEEEPDNERISYKVIAPCGCRNCEVKLRIFVHATEFGIRAFQQLLTGDLQLLCPDCRGNCKHDGS
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: AMPA_BRADU
Sequence: MSDAIKVGFVPLSAAARGILVVFCDDGLKLGPATAKALGGATELVKRAASAAAFKGKSGAALDILAPEGVKATRLIVIGAGKATGLKANDFLKFGGVAAGKLSATAAAMTIMAELPDGAMTSEQAVAIAAGLRLRAYKFDRYKTKKKDGEEGGSRADISLAVGDVAAAKKAFASAGHVVDGVIIARDLVNEPPNVLFPEEFARRASLLRKLGVKVEVLDVKAMDKLGMGALLGVGQGSTRPSRTVIMRWDGGKKGEAPVAFVGKGVCFDTGGISIKPAGSMEDMKGDMGGAACVVGLMHALAARKAKANVVGAIGLVENMPDGNAQRPGDIVTSMSGQTIEIINTDAEGRLVLADVLWYVAKKTKPKFMVDLATLTGAIVVALGTEHAGMFSNNDELADRLLTAGIESGEKVWRLPLGPEYDKLIDSQFADMKNTGGRHGGSITAAQFLQRFVDGTPWAHLDIAGTAMGAPKTDINQSWGSGYGVRLLDRLVADHYERK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y028_MYCGE
Sequence: MKRNWRQHYNVFLANLVLVFGFALNILVAKQSLNNTTPQFRFLFVTPFLGVVIGAVLYFFDVKWFLIDYPYKKFHFQKKWAIVYLSGVIVFFLNVLIGVVLLVVMVNYITNQILEREYERLFTNSLPYLWSTTGTSIVLSLISIGMSKTAHFFIDIEILKAKKGEPTDPNKTDNRAVVINLDENKKNEKEQSPPSAEMTSL
What are the official names of this protein?
Uncharacterized protein MG028.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CD5_RAT
Sequence: MDSHEVLLAATYLLGTLAAFCLGQSGRGFVGAQVMLSGSNSKCQGLVEVQMNGMKTVCSSSWRLSQDLWKNANEASTVCQQLGCGNPLALGHLTLWNRPKNQILCQGPPWSFSNCSTSSLGQCLPLSLVCLEPQKTTPLPTTTLPTTMPEPTAPPRLQLVPGHEGLRCTGVVEFYNGSRGGTILYKAKARPVDLGNLICKSLQCGSFLTHLSRIETAGTPAPAELRDPRPLPIRWEAQNGSCTSLQQCFQKTTVQEGSQALAVVCSDFQPKVQSRLVGGSSVCEGIAEVRQRSQWAALCDSSAARGPGRWEELCQEQQCGNLISFHVMDADRTSPGVLCTQEKLSQCYQLQKKTHCKRVFITCKDPNPVGLAPGTVASIILTLVLLVVLMVMCGPLIYKKLVKKFRQKKQRQWIGPTGVNQSMSFHRSHTATVRSQVENPAASHVDNEYSQPPRNSRLSAYPALEGALHRSSTQPDNSSDSDYDLQVAQRL
What is the function of this protein?
May act as a receptor in regulating T-cell proliferation.
What are the official names of this protein?
T-cell surface glycoprotein CD5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: LECT3_ARATH
Sequence: MKIQILCFTTLFLAIFTSQVTTAYKFKFDYFGNGTDPISFHGDAEYGPDTDGKSRSGAIALTRDNIPFSHGRAIFTTPITFKPNASALYPFKTSFTFSITPKTNPNQGHGLAFIVVPSNQNDAGSGLGYLSLLNRTNNGNPNNHLFAVEFDVFQDKSLGDMNDNHVGIDINSVDSVVSVKSGYWVMTRSGWLFKDLKLSSGDRYKAWIEYNNNYKVVSVTIGLAHLKKPNRPLIEAKFDLSKVIHEVMYTGFAGSMGRGVERHEIWDWTFQN
What are the official names of this protein?
Lectin-like protein At1g53070.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: RHAS_SHIFL
Sequence: MTVLHSVDFFPSCNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IQD32_ARATH
Sequence: MGRSPASSCLRLISCSGGDDTSADPNSTALENKSSGDKRGWSFRKKSGKQRGLITSVVSETTPASRTRETLESALLKSPSPDNNNVSEKQQQSFSVDEKKSQLPVVTYVAEPVDEKKTQSVIEEKTELLSVEEQIDHRTEVSPVIVESKGTETEEDDLIGTELQGPSAADAAKIEEDVTSEVEMASKVEPEESESDDVIIVRKESDEKVDEKLDESVIVVIQAAVRGFLARRELLRSKKVIKLQAAVRGHLVRSQAMGSLRCVQAIVKMQAMVRARHSTKDGSRVSATSDKSEPNAAAQKLLENKFAKHLMESTPKTKPINIKCDPTKPSSAWNWLERWMSVPKPEKTSKANLTTEEQNLEETQNVKISPQADFVNSDSTVENKTETDMPSYEASKVEGQNVELSETEKMSQYDSPEASAEVYYDSIQSQPLAAKPDSLLEEPEYVDGQIKHSLKRKVSNPSFIAAQSKFEELTSSTGSNKAMTLSSKDDVLGEEGKTDIDSPDTTNTIKDHSLEDVTPAELSGSECGTELSVTSSLDTLEKKSDAEGAEPRVEAKLLEDDTFKTDQAELIEIDVKDATSMGTVEDPKEKVENAKDEVEISATHHEPVISTPDSKKRRAEDESGPQAYALSEGALTPMTITESQATPASQASSSVKARKGKSEKSGSSQKRKVSKKITSSPKQEIGTGEATEQEEGKEQKSGRRTSFGYDQEARESSGGKNSLPRFMQPTQSAKAKVQEHNSPRSSPDLQERDVVSAKKRHSLPGVTNGKQVSPRIQRSASQAQQGTKDRKWQR
What is the function of this protein?
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).  Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).  May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
What are the official names of this protein?
Protein IQ-DOMAIN 32, AtIQD32.
What is the protein family that this protein belongs to?
Belongs to the IQD family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Note=Associates to cortical microtubules (MTs) (PubMed:24134884). Recruits calmodulin (CaM2) to microtubules (PubMed:28115582).
Protein: ARAB_ECO5E
Sequence: MAIAIGLDFGSDSVRALAVDCTTGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKILHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQIDASQKQLLPALTEAWAKNPSLDHLPVVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVPTL
What are the official names of this protein?
Ribulokinase.
What is the protein family that this protein belongs to?
Belongs to the ribulokinase family.
Protein: SYT_GLUOX
Sequence: MPAITLPDGSVRTFDGTVTGTTIAASIGPGLAKAAMAMEVDGKPVDIGTEISSDASVKFITRKDEDALEMIRHDAAHVLAEAVQSLWPETQVTIGPSIKDGFYYDFSREKPFTPEDFPAIEAKMREIVAANTPFVREVWDRDDAIRFFEEKGEDFKAQLIQDLPEDEQISIYRQGEWLDLCRGPHLRTTGDVGTAFKLMRVAGAYWRGDHRNPMLTRIYGTAWRDKKELDAHLLRLEEAEKRDHRRIGREMDLFHIQEEAVGQIFWHRKGWRLYTVLQDYMRRAQERNNYEEVRTPQLVDRALWEASGHWDKYRENMFIATVEDEDKTLALKPMNCPCHVQIFRHGLRSYRELPLRMAEFGACHRYEPSGALHGIMRVRGFTQDDAHIFCTDDQIADETAKFVKMLAEVYSDLGFDTFRVKFSDRPETRAGSDEVWDRAEGSLKKACEIAGVEYEYNPGEGAFYGPKLEFVLTDAIGRDWQCGTLQVDYVLPERLDASYIGEDSNRHRPVMLHRAILGSFERFIGILIEQYAGKFPLWLAPTQVVVASIVSDAADYANEVAATLKAAGLQVETDTRSDKINAKIREHSLARVPVILVVGRREAEERKVAMRRLGGAAQEILSLDDAVAALAKEAQAPDIARFAKD
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXC_STAAW
Sequence: MNFNDIETMVKSKFKDIKKHAEEIAHEIEVRSGYLRKAEQYKRLEFNLSFALDDIESTAKDVQTAKTSANKDSVTVKGKAPNTLYIEKRNLMKQKLEMLGEDIDKNKESLQKAKEIAGEKASEYFNKAMN
What is the function of this protein?
Implements its pathogenic function during infection.
What are the official names of this protein?
Type VII secretion system extracellular protein C, Ess extracellular protein C.
What is the protein family that this protein belongs to?
Belongs to the EsxC family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: PG172_VARV
Sequence: MMIKWIISILTMSIMPVLVYSSSIFRFRSEDVELCYGNLYFDRIYNNVVNIKYIPEHIPYKYNFINRTFSVDELDNNVFFTHGYFLKHKYGSLNPSLIVSLSGNLKYNDIQCSVNVSCLIKNLATSISTILTSKHKTYSLHRSKCITIIGYDSIIWYKDINDKYNDIYDFTAICMLIASTLIVTIYVFKKIKMNS
What are the official names of this protein?
Protein A43.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG172 protein family.
Protein: ACEK_ECO57
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAEFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_FERNB
Sequence: MSRSSKKGPFVDPKLIKKIRMLNETGEKKIIKTWSRASTIVPEMVGHTIAVYNGMKHIPVYITENMVGHKLGEFSFTRRFGGHTNKSAKKGEVKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: COAD_SHESW
Sequence: MHTRAIYPGTFDPITNGHVDLIERAAKLFKHVTIGIAANPSKQPRFTLEERVELVNRVTAHLDNVEVVGFSGLLVDFAKEQKASVLVRGLRAVSDFEYEFQLANMNRRLSPDLESVFLTPAEENSFISSTLVKEVALHGGDVSQFVHPEVTAALAAKLKLVKP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRVP_PHIOL
Sequence: MIVFILLSLAAVLQQSFGLVDFNSESPRRPEIQRVIVDTHNSYRRTVSPTASNMLRMEWYAEAAANAERWASLCAYDHSQNSDRVLDGIQCGENIYMSSNPRSWTEIMQSWYDEYKNFDFGYGANPPGSVIGHYTQIVWYKSYRIGCAAYYCPSSLYNYFYVCQYCPAGNFAGRTATPYNSGPTCGDCPSACDNGLCTNPCSEKNEFTNCNELVQQSSCQDDWIKSNCAATCFCKNKII
What is the function of this protein?
Blocks contraction of smooth muscle elicited by high potassium-induced depolarization, but does not block caffeine-stimulated contraction.  May target voltage-gated calcium channels on smooth muscle (By similarity).
What are the official names of this protein?
Cysteine-rich venom protein, CRVP, CRISP-PHI1, CRISP-PHI2, Cysteine-rich secretory protein.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
Protein: LACD2_ENTFA
Sequence: MLTLTAGKKAAMDRLSTQEGIISALAIDQRGALKKMIKALDVEPTDAQIETFKELVSKELTPYASAILLDPEYGLPAAKARDTEAGLLLAYEKTGYDATTPGRLPDLLADWSVLRLKEEGADAIKFLLYYDVDEDPEINHQKHVFIERLGSECAEEDLPFYLELVSYDAQIADATSLEYAKVKPHKVNEMMKEFSKPQYKVDVLKVEVPVNMNFVEGFAPAETAYTKEEAANYFLEQSQATDLPFIFLSAGVSTELFQETLRFAKEAGSTFNGVLCGRATWKNGVKPFVEAGETAACDWLKTEGRENIESLNEVIAATASSWHAKVQVNEG
What are the official names of this protein?
Tagatose 1,6-diphosphate aldolase 2, D-tagatose-1,6-bisphosphate aldolase 2, Tagatose-bisphosphate aldolase 2.
What is the protein family that this protein belongs to?
Belongs to the aldolase LacD family.
Protein: CNTN5_DANRE
Sequence: MKADSSSSSSMSSRMRLRNSHGVGSSSQDWSPFSRHRYSALSSQEDYRSEESEEFGPVFIQEPDDAIFSLDSDDKKIIMNCEARGNPVPTYSWLINGTNVDTEADFRYSLIDGNLIIHNASEVIDYGRYQCRAENSIGIVLSRDALLQFAYLGPFSGKTRGAVSVREGQGVVLMCAPPSHSPEIIYSWVFNELPSFVAEDSRRFISQETGNLYIPKVQPSDVGSYVCQVKNTVTNARVLSPPTPLTLKTDGVMGEYEPKIEAHFPQTVLAAKGVTVRLECFALGNPVPTITWRKMSGNIPKKARLRKSQAVLEIPNIQLEDSGSYECKAENTRGGTAFRGHLQVYTLPQWISMINDTQLDSGEQLRWECRATGKPRPTYRWLRNGEPLSTQSRVEMVNGELTIHRLQQADSGMYQCIAENKYGAIYSSAELKILASAPMFNNNPVRLIATVGKDVSLECRPRASPKPRISWRKNDRRLQPSRRIMLLRNNTLRIINSSRSDEGSYVCRAENQFGSAELTTVLLVKEPMRVELSPLRVEVTVGESVVLSCKVTHDPSLDVSFLWLLNNQPLNTQQDGGHFEYIQTQSSTADLMIRSILLKHAGKYGCRAQTSTDSVLAEAELLVRGPPGPPGVVIVEEITASTATLSWSHGVDNHSPITTYNVQARSPVSLGWQTVKTDPDPVTGSMESAMAVDLNPWVEYEFRVVATNSIGTGDPSPPSRAVRTKEAVPSVAPANVRGGNGRRHELVISWEPVSEEYQNGEGFGYIVAFRVNGTRGWKEKMVTSADSTTYKYRDETFPPLTPFEVRVGVYNNKGDGPFSEVVTVFSAEGEPREPPSEVQAFAVSSSEIKVLWKPPSPGLGRPQGYEVSFWKDVEQEELGKKKRTLGNETNMLLSGLDGNTQYLVSVKGFNSAGQGPSSTAVKISTKKNAPSLPPGNLMWIQEGNNVSLSWDPVKARDNESEVIGYKVLLRQEGRGHSQVMRTPNSAVVLTLPEGGTYIIEVRAVSEGGEGAASAQVRVLTSSGVRAKNGQLSVQNSPPGLAWTALFLSLMVPSFPL
What is the function of this protein?
Contactins mediate cell surface interactions during nervous system development.
What are the official names of this protein?
Contactin-5.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. Contactin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: CYB_DOBMI
Sequence: MTNIRKSHPLFKIINDSLVDLPAPSNISSWWNFGSLLGICLGIQILTGLFLAMHYTSDTATAFQSVTHICRDVNYGWTLRYLHANGASMFFICLFLHVGRGLYYGSYIYTETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISALVVVHLLFLHETGSNNPTGIPSDMDMIPFHPYYTIKDMLGALTMILALLVLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALMPLLHTSKQRSMMFRPLSQCLFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLILILMPLVSIVENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PSBL_TRIV2
Sequence: MERTPNPNNQPVELNRTSLYLGLLLVFVLGILFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: OTRF1_STAAR
Sequence: MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGFLGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLLLKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFPVILVTLLLTIKKRYKIGFIFWGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLGVILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIVLILLFFIINDETNWIYDGGFYLISILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPVYVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRSSYIPQFIRMVIVVTLLIPFMLILVGAFNKYGKDIIGEKANSFDTTIEDNYSMRIAPIDNIHIDGLVSEKKKESSDVYNNIKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVLELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLIDWYKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK
What are the official names of this protein?
Putative O-acetyltransferase SAR0937.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TOP3_STAA8
Sequence: MKSLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHLVTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIATDAGREGELVARLILDKVGNKKPIRRLWISSVTKKAIQQGFKNLKDGRQYNDLYYAALARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYFTLSLTVKGFDFQLESNQRYTNKETLEQMVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQDMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQVTMATTYKDQARPLMSKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLEALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKISKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADIIDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAKTFINEMKDFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPSCKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKVSRKEMKKYMNKNEGLDNNPFKDALKNLNL
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.  The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.
What are the official names of this protein?
DNA topoisomerase 3, DNA topoisomerase III.
What is the protein family that this protein belongs to?
Belongs to the type IA topoisomerase family.
Protein: GATF_CANDC
Sequence: MKAILRSSTRNLITSSRVFKNLRTSEEIRSFLAESTWSISELLQPPTGSSQTEVSPEIVKKMLKLSGLNDLKHDKSVTKALNLQMMLINHLYDNEQDTVTPSRERNDNNGIFRLLASDHLPQQPWDLDDLLKQINELKPDPSKGEVDFTISDLQRDSFVIKKEKNVK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  Required for proper protein synthesis within the mitochondrion.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial, Glu-AdT subunit F.
What is the protein family that this protein belongs to?
Belongs to the GatF family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: ATPB_TOLAT
Sequence: MSNGIIVQVIGAVVDVQFPQDAVPKVYDALKIVSEGQSKGLVMEVQQQIGGGVVRCIAMGTSDGLRRGAEVSNTGEAIKVPVGMKTLGRIMNVLGEPVDEQGPIGAEDNWVIHREAPSYEDQSSATELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYYEMKESNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFIDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSIQAVYVPADDLTDPSPATTFAHLDSTVTLSRQIAALGIYPAVDPLDSTSRQLDPLVVGQEHYETARGVQTVLQRYKELKDIIAILGMDELSEDDKLVVARARKIERFLSQPFNVAEVFTGSPGKYVTLKETIRGFKGILDGEYDDLPEQAFYMVGSIDEVVEKAKKL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.