PharMolix/UniProtQA huggingface dataset:
Protein: ANM62_ORYSI
Sequence: MFAGGADGGNGHLPRPRRARRGGGGGGGMGSPPLGPPPPPCTDYDMAYFKAYSHIGVHEEMLKDHVRTNTYRNAIMHHQDLISGKVVLDVGCGTGVLSIFCAFAGAARVYAVDASDIALQAMEIVRENELSDKVIVLHGRIEDVEIEEKVDVIISEWMGYMLLYESMLGSVIFARDKWLKPGGLILPSHASLYLAPITNSHRYQDSVYFWQDVYGIKMSSMMPLAKQCAFMEPSVETISGENVLTWPSVVAQVDCYTIQAPELETITATFNYTSMLQAPLHGFAFWFDVEFNGPVRQRSKKQANQCLDGNTQDASPSNKKKKADAPIVLSTAPEDAPTHWQQTLLYLFEPIELKKDQNIEGSVTISQSQQHARFLNICLKYFTRDQWYVKESVMK
What is the function of this protein?
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA).
What are the official names of this protein?
Probable protein arginine N-methyltransferase 6.2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT6 subfamily.
Protein: METL2_CHICK
Sequence: MAAPSEAPERRRPFGRRFLTDPTRLFQHNAWDNVEWSEEQEATAKSKVQENSSQLLPQDKQEEYEVNAKRYWDDFYKIHENGFFKDRHWLFTEFPELAPNRNPSQNEDSLCEFSCKEVSKNEGLGSCENGHCTLENRAENQLNLLKSSPRFCTEELAPQKLKQSYEDYPGSSASYRILEVGCGAGNTVFPILQTNNDPGLFVYCCDFSTTAVDLVQSNVEYDSSRCFAFVHDLCNDQSPFPMPDESLDIVILIFVLSAILPEKMQCVINKLSRLLKPGGMILLRDYGRYDLAQLRFKKGQCLSANFYVRGDGTRVYFFTQDELDDLFTRAGLQKIQNLVDRRLQVNRGKQMTMYRVWIQCKYQKPAGPQL
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of tRNA(Thr)(UGU) and tRNA(Arg)(CCU).  N(3)-methylcytidine methylation by METTL2 requires the N6-threonylcarbamoylation of tRNA (t6A37) by the EKC/KEOPS complex as prerequisite.
What are the official names of this protein?
tRNA N(3)-methylcytidine methyltransferase METTL2, Methyltransferase-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GTR1_BOVIN
Sequence: MEPTSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVQRYGEPIPPATLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTELRGALGTLHQLGIVVGILIAQVFGLDSIMGNQELWPLLLSVIFIPALLQCILLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTRDLQEMKEESRQMMREKKVTILELFRSAAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLERLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
What is the function of this protein?
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake.  Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.  Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (By similarity).  In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity).
What are the official names of this protein?
Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Photoreceptor inner segment.
Protein: MNME_SYNE7
Sequence: MVGFSGDTIAAIATAIVPQQGSVGIVRLSGAAATEIARQIFQIAGQQPWESHRILYGYIRDPESGRLVDEALLLPMLAPRSYTREDVVELHCHGGLMPVQQTLQLCIRAGARLAEPGEFTLRAFLNGRLDLSQAESIADLISAQSPQAAQAALGSLQGKLGHPIRQLRDRCLDILAEVEARIDFEDDLPPLDLEAIAAQLTAAGADMQAILSTADRGELLRTGLKIAIVGRPNVGKSSLLNAWSRCDRAIVTDLPGTTRDLVESQLIVGGIPVQVLDTAGIRETSDQVEQIGVERSRRAAQSADLVLLTIDASAGWSAEDQTIWEAVSDRPILLVINKRDRLSEAERHAIALPQQEFKAIVWTAAAQQQGIEDLEAAILAAVGTGDLTSANWDWALNQRQVAALTTAQTALRRVEETLQAQLPLDFWTIDLREAIAALGSITGEEIAESMLDLIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPYR_HUMAN
Sequence: MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYADKDVFHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWEDPGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDDPDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKSTHDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDALPPPCESACTVPTDVDKWFHHQKN
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UREF_KLEP3
Sequence: MSTAEQRLRLMQLASSNLPIGGYSWSQGLEWAVEAGWVPDVAAFERWQRRQMTEGFFTVDLPLFARLYRACEQGDIAAAQRWTAYLLACRETRELREEERNRGAAFARLLSDWQPDCPPAWRTLCQQSQLAGMAWLGVRWRIALPEMALSLGYSWIESAVMAGVKLVPFGQQAAQQLILRLCDHYAAEMPRALAAPDGDIGSATPLAAIASARHETQYSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATG7_GIBZE
Sequence: MAKPLQFAPFISEIELPFYSALFASKLDHDKLDDSARSVLGLYEPRSEEPESSCRLQILGNALTSGKTNEPSSPLATMRAEGIIRNVNTLEDFKNTDKPAMLRTAGRQVWDAIKDGSIYSVPSLLSSFIILSYADLKKYKFTYWFAFPALHSDPVWKRSGPAERLTSQETTALVDRVGTWRYSVDARERGFFLAKKVPGRRETDDPDTPQELPFHWEIGSLRDFETGFFDQVPEEDRYVAFTDPSTYPEAPGWPLRNFLILIRHRFRLTKTKVICYRDTWAKRHEAKSVILTIEMDPVENLDITEMPKVTGWARSSNGKLQAQQVNLGEYMDPARLADSSVDLNLKLMKWRIAPNLNLETIKNTKCLLLGAGTLGSYVSRNLMGWGVRKITFVDYGRVSFSNPVRQPLFNFNDCLEGGKPKALRAAEALKEIYPGVDSEGHALSVPMLGHPFTDETKTKEDYQKLEKLINEHDAIFLLMDSRESRWLPTVMGKAAGKIVMNAALGFDSYVVMRHGAETSPEGQTPLGCYFCNDVVAPADSQKDQTLDQQCTVTRPGVAPIASALLVELLTSLLQHPLGKDAPAPQPTSGVIPERDPPDHALGLVPHQIRGYTSTFQQIVIRGQSYDCCSACSPKILNAYRHDGWGFVKRALQEKEYVAELSGLAEVQRRAEEMAAHVDWEEDDDLVDDGEGELI
What is the function of this protein?
E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy (By similarity).  Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine (By similarity).  Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes (By similarity).  Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation (By similarity).  Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production (By similarity).  Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236).  Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme ATG7, ATG12-activating enzyme E1 ATG7, Autophagy-related protein 7.
What is the protein family that this protein belongs to?
Belongs to the ATG7 family.
What are the subcellular locations of this protein?
Cytoplasm. Preautophagosomal structure.
Protein: CH102_VIBVU
Sequence: MNIRPLNDKLIVERQEVENKSEGGIVLTSQSVKKSNRGKVIAAGLGKRLENGERASMEVKVGDVVIFNDGYGVKTEKMDGKEYLILSESDVLAIVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES 2, 10 kDa chaperonin 2, Chaperonin-10 2, Cpn10 2.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_VIBA3
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAIIEQDPKARVACETYVKTGMVMVGGEVTTSAWVDIEEITRETVREIGYVHSDMGFDADSCAVLNTIGKQSPDINQGVDKADPKDQGAGDQGIMFGYATNETPILMPAPITYSHLLVKKQAEVRKSGKLDFLRPDAKSQVTFQYDQGKIVGIDAVVLSTQHCDSVTTPDLREAVMEEIIKPVLPAEWINKDTNFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGMADRCEIQLSYAIGVADPTSIMVETFGTEKVAHEIIIEAVRQNFDLRPYGLQEMLNLLQPIYKQTAAYGHFGREEFPWEATDKAAILADFAGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAR1_KOMPG
Sequence: MWVLNWFQDVLASLGLWNKHAKLLFLGLDNAGKTTLLHMLKNDRLATLQPTWHPTSEELSIGNVRFTTFDLGGHEQARRVWKDYFPEVDGIVYLVDIADPERFEESRVELDALLKIEELSKVPVLVLGNKIDKSTAVSENELRHALGLMTTTGKDKVQLVEGQRPLEVFTCSIYLRQGYGEGIRWLSQYI
What is the function of this protein?
Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER).  The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.  SAR1 controls the coat assembly in a stepwise manner.  Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex.  These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles.  Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity).
What are the official names of this protein?
Small COPII coat GTPase SAR1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. SAR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PTH_MYCMM
Sequence: MAEPLLVVGLGNPGENYARTRHNLGFMVADLLAARLGAKFKVHKRSGAEVVTGRLAQRSVVLAKPRCYMNESGRQVAPLAKFYSVPPADLIVIHDELDLDFGRIRLKFGGGEGGHNGLRSVAAALGTKDFQRVRIGIGRPPGRKDPATFVLENFSSPERPEVPTICEQAADATELLVEIGLEPAQNRVHAW
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_ZYMMO
Sequence: MSRIANTFAKTKKENRAALIAFLTAGDPSIEATPALLDSLVENGVDIIELGMPFSDPMADGPAIQKANLRALAAKTGYNDIFRIATEFRKRHPETPLILMGYANPMTFKGSDSFAASAKEAGVDGIICVDIPPEEDATLGVAVREKGMDMIRLATPTSDEARLKIILDGASGFLYYVSVAGVTGLQQATEASIDAALDRIKAVTDLPVAVGFGIRSPEQAAAIAKKADAVVVGSAFVSCIEKAVTNRQDPNAALEKLAKELSTAISDARKEAAL
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: PYRI_SULIY
Sequence: MISSSKRDELIVSKIRKGTVIDHIPAGRALAVLRILGIRGSEGYRVALVMNVESKKIGRKDIVKIEDRVIDEKEASLITLIAPSATINIIRDYVVTEKRHLEVPKQIRGLIKCPNPQCITNNDVEAESRFTTISIKPLKLKCEYCEIYITEEDVIRQIL
What is the function of this protein?
Involved in allosteric regulation of aspartate carbamoyltransferase.
What are the official names of this protein?
Aspartate carbamoyltransferase regulatory chain.
What is the protein family that this protein belongs to?
Belongs to the PyrI family.
Protein: RISB_PHOPO
Sequence: MKVIEGAIVAPNAKVAIVIARFNSFINESLLSGALDTLKRQGQVSYDNITIIRCPGAYELPLVAQLTAKSDRYDAIIALGSVIRGGTHFEYVASECNKGLAQVALDYNIPVAFGVLTVDYLEQAIERAGTKAGNKGAEAALMLLEMVNILAQVES
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SPAQ_SALSE
Sequence: MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLSGWYGEVLLSYGRQVIFLALAKG
What is the function of this protein?
Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.
What are the official names of this protein?
Surface presentation of antigens protein SpaQ.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS16_ALBFT
Sequence: MVVIRLARGGAKARPFFNIVVADKRTRRDGRFIERLGFYNPIATANEESIRIAQDRLTYWRSVGAQASPTVERLISQAAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: I10R2_MOUSE
Sequence: MAPCVAGWLGGFLLVPALGMIPPPEKVRMNSVNFKNILQWEVPAFPKTNLTFTAQYESYRSFQDHCKRTASTQCDFSHLSKYGDYTVRVRAELADEHSEWVNVTFCPVEDTIIGPPEMQIESLAESLHLRFSAPQIENEPETWTLKNIYDSWAYRVQYWKNGTNEKFQVVSPYDSEVLRNLEPWTTYCIQVQGFLLDQNRTGEWSEPICERTGNDEITPSWIVAIILIVSVLVVFLFLLGCFVVLWLIYKKTKHTFRSGTSLPQHLKEFLGHPHHSTFLLFSFPPPEEAEVFDKLSIISEESEGSKQSPEDNCASEPPSDPGPRELESKDEAPSPPHDDPKLLTSTSEV
What is the function of this protein?
Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1.  The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity.  The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state (By similarity).
What are the official names of this protein?
Interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit beta, IL-10RB, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, CRF2-4, Interleukin-10 receptor subunit 2, IL-10R subunit 2, IL-10R2.
What is the protein family that this protein belongs to?
Belongs to the type II cytokine receptor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: GIGA3_CRAGI
Sequence: LQWARKRKIPSIQHDALLGKLSVSTQEGRLRDGTHDKLYSYGGRGFSVLRSDTMERIYDSGSIVEESHAMQYPKLFNSYAKSSVNITDTQDSRSDSKGPECESLAVAYSGTRVIVFVGCERPGTISIYSFNSNMTEGTLESIYSGAKTVLGTWGEAFDGGLLTDMDTDDIKYLPPFQSPTGQPLLVVTGSDTGTVSLFHVRGLDNPLPNPRVNSRVPVKPLQSSPLPESTPKSSTKTSSASPIKSRQGKKLRGKKQNKTGNTRFTYRNNKRNIKFKAGRKNNRN
What are the official names of this protein?
Gigasin-3a.
Protein: CHDH_AZOSP
Sequence: MAIKRGADLIVEALEEYGTEQVVGFIGHTSHFVADAFSKSHLGKRVINPATELGGAWMVNGYNYVKDRSAAVGAWHCVGNLLLHAAMQEARTGRIPAVHIGLNSDGRLAGRSEAAQQVPWQSFTPIARSTQRVERLDKVGEAIHEAFRVAEGHPAGPAYVDIPFDLTADQIDDKALVPRGATRAKSVLHAPNEDVREAAAQLVAAKNPVILAGGGVARSGGSEALLKLAEMVGVPVVTTSTGAGVFPETHALAMGSAGFCGWKSANDMMAAADFVLVLGSRLSDWGIAQGYITKMPKFVHVDTDPAVLGTFYFPLLSVVADAKTFMEQLIEVLPGTSGFKAVRYQERENFRQATEFRAAWDGWVREQESGDGMPASMFRAMAEVRKVQRPEDIIVTDIGNHTLPMFGGAILQRPRRLVTSMAEGILGCGFPMALGAQLAEPNSRVFLGTGDGALYYHFNEFRVAVEHKLPVITMVFTNESYGANWTLMNHQFGQNNWTEFMNPDWVGIAKAFGAYGESVRETGDIAGALQRAIDSGKPALIEIPVSKTQGLASDPVGGVGPNLLLKGREIPVDTGGSMYPGENLLHLKS
What is the function of this protein?
Catalyzes the ring-opening cleavage of the alicyclic alcohol cyclohexane-1,2-dione.
What are the official names of this protein?
Cyclohexane-1,2-dione hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: LYSX_MYCMM
Sequence: MTVTKPRSVQGRHISRYDWVPAAAGWAVGVIATLSLLASISPLVRWIIKVPREFINSYLFNFPDTSFAWSFVLALLAAALAARKRIAWLLLLTNVVLAAFLNAADIAAGGNTAAQNFGENLGFAVHVVAIVVLVLGYRQFWAKVRRGALFKAAAVLVAGGAIGILVSWGLVELFPGSLAPHDRLPYVANRVIGFALADPDLFTGRPHVFLNAMFGLFGALALIAATIVLFQSQRADNALTGEDESAIRGLLELYGNSDSLGYFATRRDKSVIFASSGRAAITYRVEIGVCLASGDPVGDPRSWPQAIDAWLRLCQTYGWSPGVMGASSQGAKAYREAGLNALELGDEAILVPADFTLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISDAEMEQTIDRADGWRDTESERGFSMALGRLGDPADTDCLLVEALDPDDLVVAMLSLVPWGTSGVSLDLMRRSPQSPNGTIELMVSELALRAEGLGISRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQIETLYRSNQKYQPQWVPRYACYEDARVIPKVGVASVIAEGFLVLPFSRRNKVHTGHHPAVPERLAATGLLHHDGSAPDVSGLRQSAIADGDDPQRRLPEQVRVRLNKLKKLRSSGIDAYPVGEPPTHTVAQAMDADDQASVSVSGRILRVRNYGGVLFAHLRDWSGEIQVLLDNSRLEQGRAADFNAAIDLGDLVEMTGQMGSSKTGTRSLIVRRWRLIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNAESRALITARSAVLRSVRETLSAKGFIEVETPILQQVHGGATARPFITHINTYSMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDSCRELIQNAAQAANGAPVAMRPAGGGRLEPVDISGVWAVKTVHDAVSEALGEQIDADTDLATLRRLADAARIPYRAQWDAGAVVLELYEHLVESRTEQPTFYLDFPTSVSPLTRPHRSKPGIAERWDLVAWGVELGTAYSELTDPVEQRLRLEEQSLLAAGGDPEAMQLDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPH
What is the function of this protein?
Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M. tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSAE_SYNSC
Sequence: MAITRGAKVRIKRPESYWFNEVGTVASIDTSGIRYPVVVRFEKVNYSGLQGVDGGINTNNFAEAELEPA
What is the function of this protein?
Stabilizes the interaction between PsaC and the PSI core, assists the docking of the ferredoxin to PSI and interacts with ferredoxin-NADP oxidoreductase.
What are the official names of this protein?
Photosystem I reaction center subunit IV.
What is the protein family that this protein belongs to?
Belongs to the PsaE family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RSP5_CHATD
Sequence: MSNNTRMDGLPAQPNLRVTIIAADGLYKRDVFRFPDPFAVATINGEQTKTTQVSKRTLNPYWNESFDFRVNEDSILAIQVFDQKKFKKKDQGFLGVINIRIGDVIDLVPDADDQMLTRDLKKSNDNLVVHGKLIINLSTNLSTPNRTQQTPSASRPSLLAPQTSTPNGTTDRPSSAMSSAVSTNGTPAASQPMPLAHRPASLASTTSTSQATAAATTSTTTATANGTPVQPRQVDVRQLSPFEDALGRLPPGWERREDHLGRTYYVDHNTRTTSWNRPTGTGQSDAEATQQAQRQQHQNRSLPEDRTGANSPTLQQQQAVAQAQATALVHTGATTAGTGELPPGWEMRWTPEGRPYFVDHNTRTTTWVDPRRQQYIRMYGGNNPNGIIQQQPVSQLGPLPSGWEMRLTNTARVYFVDHNTKTTTWDDPRLPSSLDQNVPQYKRDFRRKLIYFRSQPAMRILSGQCHIKVRRSHIFEDAFAEISRQSATDLKKRLMIKFDGEDGLDYGGLSREFFFLLSHEMFNPFYCLFEYSAHDNYTLQINPHSGINPEHLNYFKFIGRVVGLAIFHRRFLDAFFITAFYKMILGKPVTLADMEGVDADFHRSLQWMLDNDISGGIIEATFSTEDERFGVITVEDLKPNGRNIEVTNENKREYVELMVKWRIQKRVEEQFKAFKEGFNELIPQDLINVFDERELELLIGGIAEIDVDDWKKHTDYRGYTESDEVIQFFWQTVRSWDSEQKSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIERAGDINNLPKAHTCFNRLDLPPYKTLEQLQQKLTMAVEETMGFGQE
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
What are the official names of this protein?
E3 ubiquitin-protein ligase RSP5, HECT-type E3 ubiquitin transferase RSP5.
What is the protein family that this protein belongs to?
Belongs to the RSP5/NEDD4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, actin patch.
Protein: MFD_BUCBP
Sequence: MLIKSLVQKNQVYFTNNSLDEKNICDLSKLKINQPIVHFEHGVGRYQGLTTVTTRNIKTECVVINYAQNSKLYVPITYLYLISRYIGTSKKDIPLHRLGNDLWNKEKKKANEKAYDSAAILLNIYSHRISQKGFSFKKHHTKYKIFCERFPFTLTPDQDSAINSVLSDMYKSTPMDRLVCGDVGFGKTEVAMRATFLAVCNQKQVAILVPTTLLAQQHFNNFTLRFKYWSTKIEILSRFQSETKCNEIINNVNIGNVHVLIGTHKILLKNLKWKNLGLLIVDEEHRFGVHHKEQIKLISNNIDVLTLTATPIPRTLNMAFVGIRDLSIIATPPKQRLIVKTFVREFSYTVIRKAILREILRGGQVYYIYNNVNKIERKKIELKKLVPEANIRIGHGQLRSTDLESIMNDFYHKRFNVLVCSTIIETGIDIPNVNTIIIENANNFGLAQLHQLRGRVGRSQHQAYAWLLVPSLKDIKSDAKKRIDAITSIESFGSCFELANRDLEIRGIGEILGNNQSGHITKIGFSLYMKLLMNAVRNIKNGYYKPLNDIINTYPKIELNVSNLLPDSYIKKVNHRLFFYNKIATSNNFLDLEKIRLTLCKNFGNLPNSGDYLIKIAKIRLISKKIGVKKIKSDVKGGYIEFFEDSKINIQNLLKEFKKEKNCWKFDTSNRLRFSKNFKNNSERIDWILNMLININN
What is the function of this protein?
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions.  Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (By similarity).
What are the official names of this protein?
Transcription-repair-coupling factor, TRCF.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the helicase family. RecG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2735_NOSS1
Sequence: MMTPMQGVAATPINSHQFEPYTKENSEANADFSFQTLADVTKAILNHAFWLAEQKQNLSLKEYKKLLYNQGWQGEEKKYLKIAATFGKFEPQDFAQVEPRTIYQLAERNKQYQKVIDRLLDLSVINQETVRTLIQKQRTPRADRPKKPSIWRRLKNGGRYCQIPPIHEASEQTGTTLQRMMDEEGLSAQQIVAEAIALRQAYKEGQLTIS
What are the official names of this protein?
Uncharacterized protein alr2735.
Protein: CINAL_KOSOT
Sequence: MKAEIISVGTELLLGDILNTNAQYLSKKLAELGIFLYRQTVVGDNMDRILQAFDEAFKRSELVITTGGLGPTQDDLTKEAAAKFFSKKLVLHKPTLQAIKDYFKGREEYLTEGNLKQAYIPEGAIVLDNFYGTAPGCIIEDSGKILIILPGPPKEMEPMFETAVMPYLMKLQNCVLYSKVLRVFGMGECLVVEKIKEIIENQDNPTIAPYAKEGEVLLRITARADNKELAEGMIAPIEKQIREKLGEYIYGVGEESLEEIVVNLLRKTGLTISTAESCTGGLVASKIVNVAGVSKVFMEGIIAYSNEAKVKRLGVKKETLSKFGAVSEETAIEMASGIAKSAGTDIGLSITGIAGPTGGTPEKPVGLVYLGLYVNGKTAVKKLQLGGDRNKIRNRAAMFALDFVRRALLPLV
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: Y1676_OCEIH
Sequence: MSTIWVVLIAIAALVAGVALGFFIARKYMMSYLKKNPPINEQMLRTLMMQMGQKPSQKKINQMMRAMNNQSGKE
What are the official names of this protein?
UPF0154 protein OB1676.
What is the protein family that this protein belongs to?
Belongs to the UPF0154 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.