PharMolix/UniProtQA huggingface dataset:
Protein: RK4_PHATC
Sequence: MTIQKFITYTPLDLNGKQLNFNHELKLNILETSGNYLVHKDLIRHFGSQRQATSSSKTRSEVRGGGRKPWRQKGTGKARAGSNRSPLWKGGGVIFGPKPKKISLKLNKKERQLALQTLIYNKKNNILIIENLETGMTEPKTKAFVKICQDCQINLEQKVLLVVTDKTSVLKLATQNLKNVELLAASSLNTLSILKARQIILTSAAINHIKESYCD
What is the function of this protein?
Probably binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: COBQ_MYCMM
Sequence: MPGLLVAGTTSDAGKSTLTAGLCRAFARRGVRVAPFKAQNMSNNSMVCQGPGGAGVEIGRAQWVQALAANATPEAAMNPVLLKPGSDHRSHVVLMGRSWGELASSNWFEGRQVLAETAHRAFDDLAARYDVVVAEGAGSPAEINLRAGDYVNMGLACHAELPTIVVGDIDRGGVFAAFFGTIALLSAEDQALVAGFVVNKFRGDLDLLAPGLRDLEGVTGRQVFGTLPWHADLWLDSEDALDLTGRRAASTGAHRVAVVRLPRISNFTDVDALGLEPDLDVVFASDPRGLGDADLIVVPGTRATIADLAWLRARGLDRALMAHVAAGKPLLGICGGFQMLGRVIRDPDGVEGPVAEADGLGLLDVETTFGAEKVLRLPRGQGLGVTASGYEIHHGRITAGDAAQQFLGGARDGQVFGTMWHGSLEGDALREAFLRETLGLTGSGTSFSAARERRLDLLGDLVERHLDVDALLALARHGCAPALPFLPPGAP
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PROB_XANOM
Sequence: MLKVGSSLLAADGGGLSPRFALGLAQFVSANLAAGRELVIVSSGAVAAGRAILPKAVDVGAPIAARQALAALGQAQLIALWQRFFERAVAQVLLTHDDLRNRRRYLNARATLGELLRLGALPVINENDTVSVDELKLGDNDNLAAIVAALVDADALFIATDIDGLYSADPRSNPLARPLDDVPELTPEVLAMAGGSGSNVGTGGMRTKLEAAAKAGAAGIETYLFNGRSGEVVRALAQDRLRGTRIHAARTRIAARKYWLRHAPVEAGAILVDAGAAMALSDKGASLLPGGVVGAEGDFRRGDMVEIRLRDDEGERCLARGVSQYSAVDIRRIARRHSRDIENVLGYSYGENVVHRDDLVLL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOCA1_CAEEL
Sequence: MNDSCSWDQLWDQQGTLNEYTGKGIDLLERIMAYSKERASIELEYSSKLKALSKKTAMKMKSESELWNSVSYVKGFHDVIAGIVPVATQHELIAENLKSAVIPFTTQKIAEYRVAKKQLESDNSNLGKQLRMVIDEMAKSHKEYVKCYKETEAAMLKYAKAEKNMDISRLELEKTKNNYQQKCGMLEESKQTYAVMTTKANEEQSAHYDRKLPQLLDNYKKLHTNRILDTVEILSKCVEAESCVNQIIASCHNDMRRDIGLIDPSRDANLVVENMKSGHPVPQPFVFEDLGHPQDRSSFMGGGASGPAGSMDGMDATMKKGGTLMSKNGKGVARKQSMHQKFFGGGTADKKTDSGDYGTLPPQQRARKIAGKISDLEKEKDRATQSREGVSKMQAAYRENPKLGNPSDCDAQLAQYGHEIDALSNQIQKFKILLDDVNAQLGAGGLSATSVGGSDTPPSIRSVSSASSGVTSRVNTINDAHRTNGGVGGGRRESFSGSNGGSDTDPTINGNGHGRDELYEECSNPNPVLGEAIAQFAFDGAQDGTIRMEANEKLWLIEKDEGDGWTRVRKENNSADGFVPSSYLKVTWFGKV
What is the function of this protein?
Plays a role in protein trafficking, actin organization and embryonic morphogenesis (PubMed:19798448).  Potentially acts as cdc-42 effector (PubMed:25775511).  May play a role in hypodermal P-cell nuclear positioning (PubMed:23150597).  Together with toca-2, is required for protein trafficking regulating yolk protein clathrin-mediated endocytosis by oocytes during oogenesis and retrograde recycling and the sorting of recycling endosome cargo proteins such as mig-14 (PubMed:19798448, PubMed:25775511).  Also, together with toca-2, controls the distribution of actin at cell junctions (PubMed:19798448, PubMed:26578656).
What are the official names of this protein?
Transducer of Cdc42-dependent actin assembly protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the FNBP1 family.
What are the subcellular locations of this protein?
Cell junction. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Basolateral cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle. Cytoplasm. Cytoplasm, perinuclear region. Recycling endosome. Note=Co-localizes with ajm-1 at cell junctions (PubMed:19798448). Co-localizes with toca-2, rme-1, cdc-42 and wve-1 on recycling endosomes (PubMed:25775511).
Protein: DNAK_MYCSS
Sequence: MARAVGIDLGTTNSVVAVLEGGDPVVVANSEGSRTTPSVVAFARNGEVLVGQPAKNQAVTNVDRTIRSVKRHMGTDWNTEIDGKKYTAQEISARTLMKLKRDAESYLGEDITDAVITVPAYFNDAQRQATKEAGQIAGLNVLRIVNEPTAAALAYGLDKGEKEQTILVFDLGGGTFDVSLLEIGEGVVEVRATSGDNHLGGDDWDERVVTWLVDKFKASSGIDLTKDKMAMQRLREAAEKAKIELSSSQSTSINLPYITVDADKNPLFLDEQLTRAEFQRITQDLLDRTRQPFQSVIKDAGISVGDIDHVVLVGGSTRMPAVSELVKEMTGGKEPNKGVNPDEVVAVGAALQAGVLKGEVKDVLLLDVTPLSLGIETKGGVMTKLIERNTTIPTKRSETFTTADDNQPSVQIQVFQGEREIASHNKLLGSFELTGIPPAPRGVPQIEVTFDIDANGIVHVTAKDKGTGKENTIRIQEGSGLSKEEIDRMIKDAEAHADEDRKRREEADVRNQAETLVYQTEKFVKEQREAEGGSKVPEDVLTKVDGAISEAKTALAGTDIGAIKAAMEKLGTESQALGQAIYEATQAEQAAGGGAGGADGSSSSSDDDVVDAEVVDDDRENK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: ENLYS_BPPHV
Sequence: MKVSQNGLNLIKEFEGCRLTAYKPVPWEQMYTIGWGHYGVTAGTTWTQAQADSQLEIDINNKYAPMVDAYVKGKANQNEFDALVSLAYNCGNVFVADGWAPFSHAYCASMIPKYRNAGGQVLQGLVRRRQAELNLFNKPVSSNSNQNNQTGGMIKMYLIIGLDNSGKAKHWYVSDGVSVRHVRTIRMLENYQNKWAKLNLPVDTMFIAEIEAEFGRKIDMASGEVK
What is the function of this protein?
Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
What are the official names of this protein?
Endolysin, Lysis protein, Lysozyme, Muramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.
Protein: KCY_PSEAE
Sequence: MNGAVPMLAIDGPSGAGKGTVAGLLARRLGWNLLDSGALYRLLAFAAVNHGVDLTNEEALKVLAAHLDVQFVAADGSHGQRIILEGEEVTDVIRTEQVGAGASQVAALPAVRDALLQRQRAFREAPGLVADGRDMGTVVFPDAPLKIFLTASAEERARRRYLQLKAKGADVDQSALLEEIRERDERDSQRAVAPLKPADDAILLDSTEMSIEAVVETIIRHCERQGWDV
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TARI_STAS1
Sequence: MIYAGILAGGIGSRMGNVPLPKQFLDLDGKPILVHTVEKFLLTSEFDKIFIATPQKWISHTKDTLRKHHITDDRIEVVQGGSDRNETIMNIISAAEKENGISDDDVIITHDAVRPFLTRRIIKENIESVLKYGAVDTVITATDTIITSADGDSIQSIPVRSEMYQGQTPQSFNVNLLRNSYNDLSDEDKQIMTDACKILVVAGKQVKLVMGELYNIKITTPYDLKVANSIIKGGMLSD
What is the function of this protein?
Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate.
What are the official names of this protein?
Ribitol-5-phosphate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. TarI subfamily.
Protein: LOX5_ORYSJ
Sequence: MRGGAGMCFASMEAAGSRGMGKGASRRRTARSTAPVGALVERVVVAPAPVEQQRGAGRPEAHPQSVAARAVVTVRRRRKEDAKDRFAEQLDALADRVGRSVLLELVSTETDPRKGTPKKSKPSALVGWFDKKDVKAERVVYTAEFAVDAGFGEPGAVTVLNRHQREFYIESIVVEGFPTGPAHFTCNSWVQPTRVSRDRRVFFSNRPYLPSETPPGLRELRLRELADLRGDGTGERRITDRVYDYDVYNDLGNPDKGVASARPVLGGEQMPYPRRMRTGRPSTATDASAESRVEYPEPIYVSRDEEFEEGKNEMLSEGAIKALLHNFMPLLVSSVSPDIRDFAGFHDVDNLFKEGLRLKQALHDQLFQKIPFVRKIQENSEGLLRYDTPDIIKKDKFAWLRDDEFARQALAGINPVNIERLQAFPPVSKLDPAVYGPPESAITEEHIIGHLDGMSVQEAVEGSRLYMLDYHDIFLPFLDRINAQDGRKAYGTRAVFFLTAAGTLKPIAIELCLPPMTDGCKRAKRVFTPPADATSNWLWQLAKAHVCSNDAGVHQLINHWLRTHACMEPFIIAAHRQMSAMHPIFKLLKPHMRYTLKINALARQILINGDGVIESGFTPGNVCMEMSAFAYRELWRLDQEGLPADLIRRGMAVEDPSQPHGLRLLIEDYPYAADGLLLWSAISRWCEAYVAAYYPSDEAVQADYELQSWYAEAVQSGHADKRGAPWWPRLSTPGDLASLLTTLVWLCSAQHAALNFGQYPLGGYIPNRPPLMRRLVPAEGDPEYAHLVADPHRFFLSALPSLTQTTTFMTVIDTLSTHSADEEYLGERPDEAWTADPAALAAAREFAADVRRAEEEIERRNADPSRRNRCGAGVLPYELMAPSSGPGITCRGVPNSVTI
What is the function of this protein?
Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding.  Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure (By similarity).
What are the official names of this protein?
Putative lipoxygenase 5.
What is the protein family that this protein belongs to?
Belongs to the lipoxygenase family.
Protein: RIMO_ANASK
Sequence: MATRVYMHTLGCPKNRVDSEVMLGTLAEAGYRLVQDPAQAEVIVVNTCGFIESAKEESVEAIVELADQKREGRCRKLVVTGCLVQRHAEELARELPEVDHFLGTGAYQDVARIVSDAQAKRLVVPDPDFVHSSATPRVNSLPSHTAYLKIAEGCDNACAFCIIPKLRGGQRSRPIDDLVAEAAALAAQGTVELSLVAQDLTAYGQDLPGKVRLHHLLPELAKVDGIRWIRLHYAYPRDVPDALVAAIADEPRIVKYLDMPLQHSSDRLLRAMKRGRDSVFLRDLLARLRSRIPGLALRTALIVGLPGETEADFEDLLRFVEEQRFERLGVFEYSAEEGTPAAEMADQVPDAVKRERRDRIMAVQQAISRAHQQAMIGRRVEVLVEGRAEETEHLLAGRHAQQAPEIDGLTYINDGVAYPGEIVTVEITDAAEYDLVGRVVARDPSRAARPLPAAPRAAPARKGGLNVLR
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ILVC_METB6
Sequence: MMKKYYESDADLSVLSGKKIAVIGYGSQGRGQSLNLRDSGLDVIIGLRKGKSWDAAAKDGMNVMTVAEAAKKADIIQILLPDELQAAVYKNEILPHLSENKVLMFSHGFNIHFGQIQPPGNVDVIMVAPKGPGFMVRRQYEEGKGVPALIAIHQDHTCKAHKTALAYAKGIGATRAVVLETTFREETETDLFGEQAVLCGGTASLIKAGFETLVDAGYAPEMAYLEVCHELKLIVDLIYEGGLTNMRQYVSNTAQYGDMTRGPRVIGPEAYEAMEEILAEIQSGEFAKEWMLENMVNRPVFNALTKADEEHLLEETGKEVRAMMPQFRK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: PP2C3_YEAST
Sequence: MGQILSNPIIDKEHHSGTDCLTAFGLCAMQGWRMSMEDAHIVEPNLLAESDEEHLAFYGIFDGHGGSSVAEFCGSKMISILKKQESFKSGMLEQCLIDTFLATDVELLKDEKLKDDHSGCTATVILVSQLKKLLICANSGDSRTVLSTGGNSKAMSFDHKPTLLSEKSRIVAADGFVEMDRVNGNLALSRAIGDFEFKSNTKLGPHEQVVTCVPDIICHNLNYDEDEFVILACDGIWDCLTSQECVDLVHYGISQGNMTLSDISSRIVDVCCSPTTEGSGIGCDNMSISIVALLKENESESQWFERMRSKNYNIQTSFVQRRKSIFDFHDFSDDDNEVFAITTKKLQDRLNRSKDNDDMEIDDLDTELGSSATPSKLSGEDRTGPIDLFSLEALLEAGIQIRQRPSSDSDGNTSYFHGASLSDMLASLSNAAAGETEPNDADDNDDNDGEENGKNENAKKGSKIEEIE
What is the function of this protein?
Responsible, together with PTC2, for the dephosphorylation of the cyclin-dependent protein kinase CDC28.
What are the official names of this protein?
Protein phosphatase 2C homolog 3, PP2C-3.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PSAL_ISOGA
Sequence: MSEFVKPFNNDPFVGNLSTPVTTSTATKLYLGNLPIYRKGLTPLLRGLEIGMAHGYFLIGPFYILGPLRNSPNALLVGLFSAFGLIIILTLALTIYGLASFQDNGVGENLESSKGWRNFTSGFTIGALGGASVAYLVLNNISFFA
What are the official names of this protein?
Photosystem I reaction center subunit XI, PSI subunit V, PSI-L.
What is the protein family that this protein belongs to?
Belongs to the PsaL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CAPP_STRSY
Sequence: MAIQKLENYNNKEAIREEVTILTSILEEVAAQMMPAETFAKIVELSQLSRQDDYQALIAIISQLNNDELAVISRYFAVLPLLINISEDVDLAYEINHQNNIDQDYLGKISTTIDMVSKQENAAEILEKLNVVPVLTAHPTQVQRQSMLDLTKHIHELLRRYRDVKLGLLNKNKWEDELRCYIEIIMQTDMIREKKLKVTNEITNVMEYYNSSFIKAVTKLQREYKRLAAEKGIVLNNPRPITMGMWIGGDRDGNPFVTAETLKLSALTQCEVIMNYYDEQLYKLYRNFSLSTSIVNVSTAVKMLADLSEDSSVYRENEPYRRAFHYIQMKLANTRDYLVHNKPSDVRYSNVAEFKADLLAIKQSLVENKSMALLKGDFTELLEAVEAFGFYLASIDMRQDSSIHEASVAELLASARIVEDYSSLSEEAKCHVLLKQLETDPRILSATHMPKSEQLEKELAIFAAARELKDKLGEEIIKQHIISHSESVSDLLELAVLLKEVGLVDVDKARVQIVPLFETIEDLDNAPDTMRQYLQLDLAKRWIAGNKYYQEIMLGYSDSNKDGGYLSSGWTLYKAQNELTQIGQDYGVNITFFHGRGGTVGRGGGPSYDAITSQPFGSIKDRLRLTEQGEVIGNKYGNKDAAYYNLEMLVSATLDRMVTQMITDPNEIDGYRETMDEIVSDSYRIYRDLVFNNPHFYDYFFAASPIREVSSLNIGSRPAARKTITEIGGLRAIPWVFSWSQNRVMLPGWYGVGSSFKRFIDKHPDNLSKLQKMYESWPFFRSLLSNVDMVLSKSNMNIAFEYAKMCESEEVRNIFHVILDEWQLTKEIILSIEQNDELLAELPFLKASLDYRMPYFNVLNYIQIELIHRLRRGELSKEQENLIHITINGVATGLRNSG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: 6PGL_ECOSE
Sequence: MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
What is the function of this protein?
Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
6-phosphogluconolactonase, 6-P-gluconolactonase.
What is the protein family that this protein belongs to?
Belongs to the cycloisomerase 2 family.
Protein: NDK_CHLL2
Sequence: MERTLTILKPDCVRKQLIGAVIDKIERAGFRVVAMKKTRLTQETAGEFYAVHRERPFYGELVEFMSSGPCVPMILEKENAVADFRTLIGATDPAQADEGTVRKLYADSKGENIVHGSDSAENAAVEAGFFFSAEEVVRVD
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KITH_EBVA8
Sequence: MAGFPGKEAGPPGGWRKCQEDESPENERHENFYAEIDDFAPSVLTPTGSDSGAGEEDDDGLYQVPTHWPPLMAPTGLSGERVPCRTQAAVTSNTGNSPGSRHTSCPFTLPRGAQPPAPAHQKPTAPTPKPRSRECGPSKTPDPFSWFRKTSCTEGGADSTSRSFMYQKGFEEGLAGLGLDDKSDCESEDESNFRRPSSHSALKQKNGGKGKPSGLFEHLAAHGREFSKLSKHAAQLKRLSGSVMNVLNLDDAQDTRQAKAQRKESTRVPIVTHLTNHVPVIKPACSLFLEGAPGVGKTTMLNHLKAVFGDLTIVVPEPMRYWTHVYENAIKAMHKNVTRARHGREDTSAEVLACQMKFTTPFRVLASRKRSLLVTESGARSVAPLDCWILHDRHLLSASVVFPLMLLRSQLLSYSDFIQVLATFTADPGDTIVWMKLNVEENMRRLKKRGRKHESGLDAGYLKSVNDAYHAVYCAWLLTQYFAPEDIVKVCAGLTTITTVCHQSHTPIIRSGVAEKLYKNSIFSVLKEVIQPFRADAVLLEVCLAFTRTLAYLQFVLVDLSEFQDDLPGCWTEIYMQALKNPAIRSQFFDWAGLSKVISDFERGNRD
What is the function of this protein?
Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis.  The dTMP serves as a substrate for DNA polymerase during viral DNA replication.  Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors.
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae thymidine kinase family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus. Note=Localizes to the centrosome and more precisely to the periphery of the centriole, tightly encircling the tubulin-rich centrioles.
Protein: ST2B1_MOUSE
Sequence: MDGPQPRALWSSSEKNVSEMSWNFGGEYFRYKGIPFPVGMYSPESLSLAENTSNVRDDDIFIVTYPKSGTNWMIEIVCLILKDGDPSWIRSEPIWQRAPWCETIISAFNVLDRPSPRIMSSHLPIELFTKAFFSSKAKVIYVGRNPRDVVVSLYYYSKIAGQLKDPGTPDQFLQNFLKGEVQFGSWFDHIKGWIRMQNQENFLFITYEELQQDLRGSVQRICEFLGRPLGEEALSSVVAHSAFAAMKANTMSNYSLLPASLLDHRQGEFLRKGISGDWKNHFTVAQSEAFDSVYREQMHGVQRFPWDTSEEDSSPDGQPDPEPSPSPASDDPNPGSSQ
What is the function of this protein?
Strongly sulfonates pregnenolone, however is capable to sulfonate cholesterol with a high degree of efficiency.  DHEA is a relatively poor substrate.
What are the official names of this protein?
Sulfotransferase 2B1, Alcohol sulfotransferase, Hydroxysteroid sulfotransferase 2, Sulfotransferase family cytosolic 2B member 1, ST2B1.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Microsome. Nucleus.
Protein: NU6M_PHOVI
Sequence: MMTYIVFILSIIFVVSFVGFSSKPSPIYGGLVLIISGAVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMAIEQYPEVWVSNKAVLGAFVMGLLSELLLACYILKDDEVDVVFEFNGMGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSLLTGVLVIMEVTRGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DXR_NITMU
Sequence: MIAVRHLTILGSTGSIGVSTLDVVARHPDRFRVVALTANKSVQKILEQCRRFEPRYAVLLDEASAELLQVEIRRAGLATEVLWGVDSLEKVASLPDVDTVMAAIVGAAGIRPTFAAAATGKRVLLANKETMVMAGRIFTDVVKENHATLLPIDSEHNAIFQSLPQHFSGDLRAVGVRRILLTASGGPFRQMPLAALENVTPGQACAHPNWVMGQKISVDSATMMNKGLEVIEAHWLFEASPEQIEVVVHPQSIIHSMVEYVDGSVLAQLGNPDMRTPIAHALGFPERIETGVNPLDMFKVARLDFEAPDFERFPCLRLAYQALASGGSAPAVLNAANEVAVDSFLKCLMPFTSIPAMIEDVMQTIGRRDIATLDDVLAADGMAREAAQEWLTCLA
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: QUEA_LEGPA
Sequence: MNKQDFYFDLPSELIAQYPLANRSDSRLLIYNRQTEEYGHYQFREIADFLQPGDLLVMNDSKVIPARLYGHKATGGKVELLVERITGDFTFLAHIKASKSLKSNDLIYLDAGKRLEVLERQDDLFLCKASENILDLLNDLGHIPLPPYIAREDESLDKERYQTVYAKCAGSVAAPTAGLHFDDAVLSSIRARGVNIAYVTLHVGAGTFRPVRCERIQDHKMHSEWFTVSPDLCAAVKAAKSMGNRVIAVGTTALRSLESAAMGGELIPCSRDTDIFIYPGYQFKVCDGLITNFHLPESTLVMLVSAFIGHQECMALYQEAIDKRYRFFSYGDASLLL
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_THEAC
Sequence: MNLIEYEAYFWAKFFVAERAVSGVIIILIYLIIASVLAYILSFHIAKIYLDEKTVFSKITGRIISFFERMIGESPDHGMTFKEYFINLLLFNFFAGLISFLVIMFQKYLPFSYDTVGMSPSLDFNTVVSFLTNTNLQHYSNPMRLSYFSQTFVITGLMFLSAGTGFAASMAFVRGIRTDTGNIGNFYHDFLVSIFDLILPLTVILTVILILAGIPETMQRYITVNAFLTNKVYNIPLGPVATLEAIKNIGTNGGGFYGANAAYPFENPDWFTNLVEFVSFVIIPLASLISLGIVFGDRKFGRMLYWVVMFFFIFDALFAFFGEFAGVPFLHLGYYTGNMVGKETAIGISQSTIFAVGATITSTGASNAALVSYTPAGIIGVLIGLLLNDPLGGVGTGVLNIFMYIIFTVFIASLMVGKLPEIMSLRISSKEIKYSTLSLITHPLLVVIPLGITLMIPHLMSSFVNPESSRITELLYEFASAASNNGSEMGGFITNQPFFNYLDGVLMLLGRYLLMAFQLIIAQSFSVKKAKAQYYRSIDTSNWIFGVLLIAAMILIGLLSYFPIIVLGPLLSWAHDFNLILEAMV
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NADE_STRP8
Sequence: MTLQEEIIRQLGVKASIDPKEEIRKTVDFLKTYLRKHSFLKTYVLGISGGQDSTLAGKLAQMAIAELREETGDQAYQFIAVRLPYGVQADEADAQKALAFIMPDQTLTINIKAAVDGQVAALQEAGIEISDFNKGNIKARQRMISQYAIAGQMAGAVIGTDHAAENITGFFTKFGDGGADILPLFRLNKRQGKALLKVLGADAALYEKVPTADLEDQKPGLADEVALGVTYQDIDDYLEGKLISKVAQATIEKWWHKGQHKRHLPITIFDDFWK
What is the function of this protein?
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD.  Uses ammonia as a nitrogen source.
What are the official names of this protein?
NH(3)-dependent NAD(+) synthetase.
What is the protein family that this protein belongs to?
Belongs to the NAD synthetase family.
Protein: TRMN6_HISS2
Sequence: MAKKQEFTFKQFHINQDQCAMKVGTDGILLGAWANINQANTLLDLGTGTGLIALMLAQRSPEHCQISAVELDQLAYLQAKDNIQQSPWANKIKIFQQDIIVFAQDCEHKFDVITANPPYFKQGVDCASKQRNLARYTLTQSHLDWLNAAEKLLNLTGEIHLILPFEEGKSLQKKCGLFCIRECKIITKAGKTPQRLLLSFSREERKCEESQLVIYDRNNQYSTEFKTLTQDFYLNF
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1233_THIDA
Sequence: MSQLVDRRLSGKNRSAVNRQRFLRRFKAQIRKAAAQAVSGRKVADLERGEKISIPSKDLSEPIFHHGPGGRRNVILPGNREFVSGDRIDRPAGEGGGGSGGSPDGEGMDDFVFELSKEEFMDYFFEDLALPDMVKKQLAAVPEVKKSRAGFVSHGNPANLHVVRSMKQAIGRRLAMAAGPREALRQAEEALEALVAEGRGAEPDAEALREEIAALKARVAAVPFIDTWDLRYAHRVDQPVPSSQAVMFCLLDVSGSMDEDRKNIAKRFFMLLYLFLTKSYERIDVVFIRHHTVAKEVDEEEFFSSRESGGTVVSSALELMRDIILARYPTSNWNIYAAQASDGDNWDDDSPRCRDLLLQSILPLTQYFAYVEIEAEEPQSLWREYERVKAASPRFAMQRILALEDIYPVFRELFRKKAA
What are the official names of this protein?
UPF0229 protein Tbd_1233.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: CSPB_GEOSE
Sequence: MQRGKVKWFNNEKGYGFIEVEGGSDVFVHFTAIQGEGFKSLEEGQEVSFEIVQGNRGPQAANVVKL
What is the function of this protein?
Affects cell viability at low temperatures.
What are the official names of this protein?
Cold shock protein CspB, Major cold shock protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TDX_ORYSJ
Sequence: MATAGASSFEDEIMESDIELEGEAVEPDNDPPQKMGDPSVEVSDEKRDQAQLCKNKGVDAFSEGKLDEAIEHLTEAIVLNPTSAIAYATRAVIFVKSKKPNAAIRDADAALKINPDSAKGYKSRGMAKAMLGKWEEAAQDLRMAAKLDYDEEIGAELKKVEPNVLKIEEHRKKYERLRKERDIKKAEMEKQRKHAEEVSAASAALKDGDVIAIHSSSELDTKLKAASSLSRLVVLYFTAAWCGPCRFIGPVCKSLAEKHRNVVFLKVDIDELNSVAYRWNVSSVPSFFFVRNGKEIDKVVGADKNGLERKVAQHGSS
What is the function of this protein?
Probable thiol-disulfide oxidoreductase that may participate in various redox reactions and act as chaperone under heat shock.  May interact with HSP70 proteins through the TPR repeats (By similarity).
What are the official names of this protein?
TPR repeat-containing thioredoxin TDX, OsTrx26, Tetratricoredoxin, OsTDX.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.