PharMolix/UniProtQA huggingface dataset:
Protein: KCY_LIMRJ
Sequence: MCKGLQVAIDGPASAGKSTVAKLVAKKFNYVYCDTGAMYRAVTLAVLNQGIDPKDDKKVAEIARQIKIDFEPGEIEQRVFLDGKEVTHDIRLPKVAANVSAVAAVPAVREEMTKQQRQIAENGGIVMDGRDIGTTVLPQAPVKIFMVASAYERARRRYAENQAKGINTTSLEELQKAIELRDKKDSTRKVSPLTQAPDAIKLDTTNMTIDEVVSEISKIIKKTQDELA
What are the official names of this protein?
Cytidylate kinase, CK, Cytidine monophosphate kinase, CMP kinase.
What is the protein family that this protein belongs to?
Belongs to the cytidylate kinase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HACD4_BOVIN
Sequence: MGPVALPTWLQPRYRKNAYLFIYYLIQFCGHSWIFTNMTVRFFSFGKDSMVDTFYAIGLVMQLCQSISLLELLHIYVGIESNHLLPRILQLTERIIVLFMVITSQEEVQEKYVVCVLFIFRNLLDMVRYTYSMLSVIGISYAVLTWFSQTLWMPIYPLCVLAEAFTIYQSLPYFESFGTYSTKLPFDLSFYFPYVLKIYLMMLFVGMYFTYNHLYSERRDILRVFPNKKKM
What is the function of this protein?
Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle.  This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle.  This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation.  Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
What are the official names of this protein?
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4, 3-hydroxyacyl-CoA dehydratase 4, HACD4, Protein-tyrosine phosphatase-like A domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the very long-chain fatty acids dehydratase HACD family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: AT5F1_BOVIN
Sequence: MLSRVVLSAAAAAAPSLKNAALLGPGVLQATRIFHTGQPSLAPVPPLPEHGGKVRFGLIPEEFFQFLYPKTGVTGPYVLGTGLILYLLSKEIYVITPETFSAISTIGFLVYIVKKYGASVGEFADKLNEQKIAQLEEVKQASIKQIQDAIDMEKSQQALVQKRHYLFDVQRNNIAMALEVTYRERLHRVYREVKNRLDYHISVQNMMRQKEQEHMINWVEKRVVQSISAQQEKETIAKCIADLKLLSKKAQAQPVM
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
What are the official names of this protein?
ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase peripheral stalk-membrane subunit b, ATP synthase subunit b, ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ATPase B chain family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: TMED2_RAT
Sequence: MVTLAELLVLLAALLATASGYFVSIDAHAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLKRFFEVRRVV
What is the function of this protein?
Involved in vesicular protein trafficking.  Mainly functions in the early secretory pathway but also in post-Golgi membranes.  Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side.  In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER.  Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1.  In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place.  Involved in trafficking of G protein-coupled receptors (GPCRs).  Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization.  Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting.  Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus.  May also play a role in the biosynthesis of secreted cargo such as eventual processing (By similarity).
What are the official names of this protein?
Transmembrane emp24 domain-containing protein 2, COPI-coated vesicle membrane protein p24, Membrane protein p24A, RNP21.4, p24 family protein beta-1, p24beta1.
What is the protein family that this protein belongs to?
Belongs to the EMP24/GP25L family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Note=Cycles between compartments of the early secretatory pathway.
Protein: UREE_STAA2
Sequence: MIVEEIQGNIANLSNSEKQKHVEKVYLENSDLVKRIQRVVTDHGTEIGIRLKQPIDLQYGDILYADDHNMIIVDVNSEDLLVIQPRTLQEMGDIAHQLGNRHLPAQFTETEMLVQYDYLVEDLLKSLGIPYVREDRKVNKAFRHIGHSHD
What is the function of this protein?
Involved in urease metallocenter assembly.  Binds nickel.  Probably functions as a nickel donor during metallocenter assembly.
What are the official names of this protein?
Urease accessory protein UreE.
What is the protein family that this protein belongs to?
Belongs to the UreE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPK1_MYCBP
Sequence: MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREASEEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADPNVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVHVAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENIIVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTASPQEGHSVRDHQESLMERHRSP
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: P5I11_BOVIN
Sequence: MAAKQPPPLMKKHSQTDLVSRLKTRKILGVGGEDDDGEVHRSKISQVLGNEIKFAVREPLGLRVWQFVSAVLFSGIAIMALAFPDQLYDAVFDGAQVTSKTPIRLYGGALLSISLIMWNALYTAEKVIIRWTLLTEACYFSVQFLVVTATLAETGLASQGILLLLASRLLFVAISVYYYYQVGRKPKKV
What are the official names of this protein?
Tumor protein p53-inducible protein 11, p53-induced gene 11 protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYC_HELHP
Sequence: MITLFDSAKKQKIPFTPIQDNQIRLYVCGPTVYDDAHLGHARSSIVFDLWRRLFLFLGFEVVFVKNFTDIDDKIIKKSLQNNASVQEIGSHYIHSYLKDMASLGVLRADIEPKATDNLPQMCEMIQTLLHKGYAYEGENSDIYLRIHKDKNYGALSQRLEQSHTQSRIQNAQDKLEHNDFALWKGYKGENDIAYDSPFGKGRPGWHIECSAMIEKHLAYQNEEYGIDIHAGGSDLLFPHHENEASQTRCATGREIAKYWLHNGFVNINGEKMSKSLGNSFFIKDALKVYDGEILRNYLLGVHYRLALNFNEEDLLQSKKRLDKLYRLKKRVIESHIQSPQITREEIKQFTHNIKETAKEAHKTFLSSLVEALSDDYNISKALSIIEDMLSTSNEYLDKNPKDKAYKQAIKANLACIEFLLGLGGKSTQSYFQLGLDEKTKQEIESKIAKRQEAKAQKNYALADKLRDELKSQGIEIMDTPQGSTWEKI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_ACET2
Sequence: MIILVDAMGGDNAPEAIVNGCLDAVSEADGFEILLIGDEGKIREILNKRSYDTSRIKIHHASEVITVEDTPTKAIKTKKDSSMVVGFKLLKEKKGDIFLSCGNSGALMTGALFILGRIKGVDRPAIGAIVPTKAGKGLIIDAGLNTVCKPVNYQQFGIMGSIYMKEMLGIENPKVGLLNIGAEVGKGNETLKQAYSLLSESNINFVGNVEGNDVALGKVDVVVCDGFTGNVLLKFYEGAGSYFYNLIKGIMLKNLKTKMAALMLKKDMKVLKKIMDADENGGAPILGVDGLVFKSHGSSNARTVKNVIIKASKFAETKALDKIRQEFVNMEVEDIEQDL
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: RL19_BUCAP
Sequence: MTNIIQEIEQEQLKENIPHFRPGDTVEVKVWVIEGSKKRLQSFEGIVISIKNRSLNSSFTVRKVSNGEGIERVFQTHSYSIDSIFVKRKGKVRKAKLYYLRTRTGKSARIKERIE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: QPCT_IXOSC
Sequence: MLFPVLLLLKLVIGALIIDASALSWHDLKWPRDLRPLAHHDLLYMGQISEEDRGDFNATLRNFLVPRVVGSQKHREVREFIVRSLKDLDWDVEEDCFDGQTPHGIKPFCNVIATLNPSACHRLVLACHYDSLLHKEGTFIGATDSAVPCAQLLYLARSLNGKLQNQKTRGDGLTLQLVFFDGEEAFERWSSHDSLYGSRHLAQKWHEDRTSAERLESCLERSEIANQIDRMEVMVLLDLLGAENPRFYSYFGETQPVYRRLVNIESRLNDAGLMELPRRRRRTNYFSNSSTVGFIEDDHIPFLKRSVPIVHIIPSPFPDVWHTLDDNEQNLHHPTISNLNKIFKAFVSEYLQL
What is the function of this protein?
Responsible for the biosynthesis of pyroglutamyl peptides (PubMed:23770496, PubMed:24598748).  Seems to have a preference for substrates with neutral or hydrophobic amino-acid residues at the second and third positions (PubMed:24598748).  Shows activity towards the peptides [Gln-1]-corazonin, [Gln-1]-periviscerokinin and [Gln-1]-sulfakinin (PubMed:24598748).
What are the official names of this protein?
Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, Glutaminyl-tRNA cyclotransferase.
What is the protein family that this protein belongs to?
Belongs to the glutaminyl-peptide cyclotransferase family.
What are the subcellular locations of this protein?
Secreted.
Protein: IAAA_SALTY
Sequence: MNKAVIAIHGGAGAIARAQMSHEQELRYIQALSEIVESGQKMLEAGDSALDVVTEAVRLLEACPLFNAGIGAVYTRDGTHELDACVMDGNTLKAGAVAGVSHVRHPVLAARLVMERSPHVLMVGEGAENFAFSQGMARVSPDIFSTPARYEQLLAARAAGEMALDHSGAPLDETKKMGTVGAVARDKFGNLAAATSTGGMTNKLPGRVGDSPLVGAGCYANNASVAVSCTGTGEVFIRTLAAYDIAALMEYGGLSLADACERVVMEKLPALGGSGGLIAVDHEGNVALPFNSEGMYRAWGYAGDTPTTGIYRE
What is the function of this protein?
Degrades proteins damaged by L-isoaspartyl residue formation (also known as beta-Asp residues).  Degrades L-isoaspartyl-containing di- and tripeptides.  Acts best on iso-Asp-Leu, followed by iso-Asp-Ala, -His and to a lesser extent iso-Asp-Lys, -Phe and iso-Asp-Leu-Ala.  Does not act on internal iso-Asp bonds (Als-iso-Asp-Leu-Ala).  Does not act on alpha-Asp bonds.  Has poor L-asparaginase activity.
What are the official names of this protein?
Isoaspartyl peptidase, Beta-aspartyl-peptidase, Isoaspartyl dipeptidase.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: RS16_ACIF5
Sequence: MVVIRMARGGAKKRPFYHIVVADSRSRRDGRFIERLGFYNPIGAVAELRIDKERAAYWLSQGAQPSDTVAGFLKKEGVSKTGVASV
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TIG_ECOLU
Sequence: MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEAEDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
Protein: IHFA_BUCA5
Sequence: MVLTKAAISENLFEKLQLTKKESKEFVEFFFEEVRKSLEKGEAVKLSGFGNFQIKKKKARPGRNPRTGEIFLITARRVVTFKAGQKLKNKINNYLIKKNNNF
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: CDTB_SALTI
Sequence: MKKPVFFLLTMIICSYISFACANISDYKVMTWNLQGSSASTESKWNVNVRQLLSGTAGVDILMVQEAGAVPTSAVPTGRHIQPFGVGIPIDEYTWNLGTTSRQDIRYIYHSAIDVGARRVNLAIVSRQRADNVYVLRPTTVASRPVIGIGLGNDVFLTAHALASGGPDAAAIVRVTINFFRQPQMRHLSWFLAGDFNRSPDRLENDLMTEHLERVVAVLAPTEPTQIGGGILDYGVIVDRAPYSQRVEALRNPQLASDHYPVAFLARSC
What is the function of this protein?
Produces a CDT (cytolethal distending toxin) activity, which causes DNA damage in intoxicated cells.  This damage induces G2/M cell cycle arrest, chromatin fragmentation, cell distention and nucleus enlargement.
What are the official names of this protein?
Cytolethal distending toxin subunit B homolog, CDT B, Deoxyribonuclease CdtB.
What are the subcellular locations of this protein?
Secreted. Note=Localized to the nucleus of infected cells.
Protein: RBSA1_ECO57
Sequence: MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFESCDDVTVFRDGQFIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISEDRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIILVSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GARL_ECOUT
Sequence: MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: T7496_ILLWI
Sequence: MLKFVVLIFVVIMASTFAEQCGDKVCGEGTCCSEFPVVHCRELGIVDDLCMSPGETTDSGRYLFFCPCETGLRCDKNDWTCKQDSSRSE
What are the official names of this protein?
U1-hexatoxin-Iw1e, U1-HXTX-Iw1e, Atracotoxin-Hs20f7496, AcTx-Hs20f7496.
What is the protein family that this protein belongs to?
Belongs to the MIT-like AcTx family.
What are the subcellular locations of this protein?
Secreted.
Protein: CYSD_ECO7I
Sequence: MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: RF1_NITHX
Sequence: MSSLPEAKLDILLARHAALENELLSQISAERYVQMTRELSELNPVVEAVKNWRAVKTEIAGIDAMIADPATDAEMRAMAEAERPALGARGDELAQKIRVALLPKDAMDERNVMLEIRAGTGGDEASLFAGDLFRMYERFAGLQGWKVEAISASEGTMGGYKEIVAEVRGRGAYAKLKFESGVHRVQRVPDTETQGRVHTSAATVAVLPEAEEVDVDIKTDDLRIETMRAQGAGGQHVNKTESAIRITHIPTGIVVMMQDSRSQHKNRASAMNILRSRIYDAERQRINAARSADRKDQVGSGDRSERIRTYNFPQGRVTDHRINLTLYKLPQVIAGDALHELIDALTTEHQAAQLATEGGGA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEI_DROME
Sequence: MKSNTYELHNYADLNDMARATDSKDSRKRKTASARGEKYSLRQKRQKRGSNEDGESANLADFQLELDPIAEPASKSRKNAPTKSKTKAPPLSKYRRKTANARERTRMREINTAFETLRHCVPEAIKGEDAANTNEKLTKITTLRLAMKYITMLTDSIRDPSYESEFIGECLEESANREARVDLEANEEAEVELPVPVAKKPAKTKGSGKKSSAASKRQSQKQAKIVPQIPPISSGESCYATSSIGSPASSAYASLSSSSNSHSSSSSPGLELDSLVGLNGISALDSLLLDTSDGDSLSCLSPGYGSLLTGSGESLLPGCRGDLPMSGLEKSDVELSLRLLDQSSKDSFDFASDQQPSACISSFSALDGYPFDLLHSDFPDMFLT
What is the function of this protein?
Probably plays an important role in the differentiation of epidermal cells into the tendon cells that form the attachment sites for all muscles.
What are the official names of this protein?
Helix-loop-helix protein delilah, Protein taxi.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFP_THENN
Sequence: MIEVGDLKKGMFIIYDGEIYRVLEASKHFMGRGSGLVRTKLKNVKTGLVREVNFPSGEKVPEAELSFRKAQYLYRDGDHYYFMTLDDYEQHALSEEEIGDAKYYLVENMEVDLVFHEGVPIGVELPTTVELTVVETEPSFKGDTVSGGGKPAVLETGLKITVPYFIETGDKIKVDTRTGEYVGRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHD_BORPD
Sequence: MNTADSSLLADIREVNLSYLLLAQRMLRDDYAASMFRLGFSNEVADILMRLSPAQLVKLAGSSSLLCRFRFDDYSLLSALTQDVLGGALQQAHATILLAKQPVEQLA
What is the function of this protein?
Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhD.
What is the protein family that this protein belongs to?
Belongs to the FlhD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEUA_ONCMY
Sequence: MAAAKKRTQSDIEDVRDRKAKVIKDSGEKRHIAALILARGGSKGIPLKNIKVLAGVPLIGWVLRAAVDSKQFDSVWVSTDHDDIEKVAKTWGAQVHRRSPEVSKDSSSSLDTIQEFARLNPEVDVICHIQATSPCLHPFHLKEALEMITKQGFTSVFSVVRRHHFRWQEVKKGGSVATQPLNLDPCNRPRRQDWDGELCENGSFYIYTRATIERGLQGGKWAYYEMLPEYSVDIDVDIDWPVAEQRVLRFGYFGLDKPEVVRLLLCNVSGCLTDGRVLISVSGEEMVSVNTRDTMGIRMLQREGVEVILISSSEDLLTKALADNLSQRTGCEVRQLGKDIQGEVIAMMDDKDLDWKEVAYMGNDAPDVDCLNLAGLSAVPRDAPVVAINAAKYSCHSAAGLGAVREFSEHILLLKKKAKSQMEQDRIHRNTF
What is the function of this protein?
Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid.
What are the official names of this protein?
N-acylneuraminate cytidylyltransferase, CMP-N-acetylneuraminic acid synthase, CMP-NeuNAc synthase.
What is the protein family that this protein belongs to?
Belongs to the CMP-NeuNAc synthase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GCSH_SHESM
Sequence: MSNIPTELKYASSHEWIRKEEDGSYTVGITEHAQELLGDMVFVELPEVGDTVTAGDDCAVAESVKAASDIYAPISGEVIAVNEALEDSPELVNSDAYGEGWFFRVMPSDESEVDALLDAEGYQAVIDEE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: RK2_NYMAL
Sequence: MAIHLYKTSTPSTRKGAVDSQAKSNPRTKLIYGQHRCGKGRNARGIITARHRGGGHKRLYRKIDFRRNEKDISGRIVTIEYDPNRNAYICLIHYGDGEKRYILHPRGAIIGDTIVSGTEVPISMGNALPLTDMPLGTAIHNIEITLGKGGQLARAAGAVAKLIAKEGKSATLRLPSGEVRLISKNCSATVGQVGNVGANQKSLGRAGSKCWLGKRPVVRGVVMNPVDHPHGGGEGRAPIGRKKPTTPWGYPALGRRSRKRNKYSDIFILRRRK
What are the official names of this protein?
50S ribosomal protein L2, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SCR1_ORBFA
Sequence: MEAKFRLSLLLIILGALAVHGARLENKLENPLPVGAKRSVNCQSMNGICMYGNCPAGTTFCGYDPYTCGSPPGMCCCYD
What is the function of this protein?
Induces neurotoxic symptoms on zebrafish (By similarity).  Has also been claimed to be implied in calcification, but tests on homolog proteins suggest that proteins of this family have a neurotoxic function and not a calcification function (PubMed:19283069).
What are the official names of this protein?
Small cysteine-rich protein 1, Mfav-SCRiP1, SCRiP1.
What is the protein family that this protein belongs to?
Belongs to the Cnidaria small cysteine-rich protein (SCRiP) family.
What are the subcellular locations of this protein?
Secreted. Nematocyst.