PharMolix/UniProtQA huggingface dataset:
Protein: PUB1_MEDTR
Sequence: MNDPRSKMMISPGLLPTESLLDSLILISNEVSSMQKFPLVQIKNVSSMIRRIKLLSSLFEEIQESDSPLPPSSILCFIEIFSVITRVKVLIQECTDGSSLWSLIQLDFISNQFFVLVKEMGRALDILPLNLLNVAQDIKEQVDLLHKQSKRVELELFIDPREVQRRENLFEVMSKNCLQNKKTNNNKGFIDFVKVEEIMCSIGLRTLSDYVEEISKLEVEAQNQAGTGGLIVVSNINNLMSLVSYTKSMVFRNDGESEECKPISMFLYNKSKIHDNDSSSSSSFSQSMMTVNIPDEFRCPISLDLMRDPVIVSSGHTYDRISIAEWINSGHHTCPKSGQRLIHTALIPNYALKSLVHQWCYENNVKMNEAITKNNNSSSKRHKNENAIDHISENKASKDAVKMTAEFLVGKLATGSTDIQRQSAYEIRLLAKTGMDNRRIIAEVGAIPFLVTLLVSKDSRIQEHVVTALFNLSIYDNNKILIMAAGAIDNIVEVLEFGKTMEARENAAAAIYSLSMIDDCKVQIGASSRAIPALVGLLKEGTIIGKRDAATALFNLAVYNPNKLSIVKSGAVTLLVELLMDDKAGITDDSLAVLAVLLGCSEGLEEIKNSKSLVPLLIDLLRFGSVKGKENSITLLLGLCKEEGELVAMRLLANPRSIPSLQSLAADGSLRARRKADALLRLLNRCCSQPHHSL
What is the function of this protein?
Exhibits U-box-dependent E3 ubiquitin ligase activity in vitro (PubMed:20971894, PubMed:26839127).  Negatively modulates successive stages of infection and development of rhizobial (e. g.  Sinorhizobium meliloti) and arbuscular mycorrhizal fungi (AM, e. g.  Rhizophagus irregularis) symbioses, in an ubiquitin ligase activity-dependent manner (PubMed:26839127).  Negative regulator of the LYK3 signaling pathway leading to nitrogen-fixing symbiosis (eg.  infection and nodulation) by rhizobia.  May be involved in the discrimination of rhizobium strains producing variant Nod factors (PubMed:20971894).
What are the official names of this protein?
U-box domain-containing protein 1, Plant U-box protein 1, MtPUB1, RING-type E3 ubiquitin transferase PUB1.
What are the subcellular locations of this protein?
Cell membrane.
Protein: NORD_BRUSU
Sequence: MLDFLELEETVGRAWHRLIGKTGSWPQYPDHAVQLVDIRQRLAICFRGFGGDIAVQIAPARARTSTHRLGLRRRMALGEEKLAQPLRDEATLMLPPEIALFPDRQLNYDLYVWLVGYMAVMPMDADALPEDALRRDLAALQIAEQTVERACRAFPGLKPRYKRLCAAILAERPKRPLHRLEQQVEARILSLLKQGADLPDDALPTIFPHRGPAGYLPALPVPLWPGLMKREEVAPRTGEDEPVRNSQSEGAETGRQIAQRERQDPRHADRSPFILNRFEKILAMAEMVSVDRPSDDSDEQNAKSADELDDLTLGERKGRPAARFRFDLDLPPEAVDRSLLTAELTYPEWDYRKGAYLPDHCAVLAAPVQEKEKPLELDAAAQSLVRRVRRQFEILRPGREVLRAQLDGTDLDLDAVVRSRCDLAAGGQGSDRVHLMSRPQANDLAVTLLVDVSLSTDAWVDNRRVLDVEKEALLVLANGIAACGDRCSILTFTSRRRSWVRVETVKDFDESFGPTVEHRIAALKPGFYTRMGAAMRHATAKLAEQPNRKKLLLLLTDGKPNDVDHYEGRFALEDSRRAAGEARAKGVNVFAVTVDREASAHLPALFGRGGYALVANLAKLPVALPAIYRMLAG
What is the function of this protein?
Part of the operon norEFCBQD encoding nitric oxide reductase.  Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection.
What are the official names of this protein?
Protein NorD.
Protein: ATPA_XENLA
Sequence: MLSVRVAAALARALPRQSGLVSKKALGAAFVATRNIHASGVWPPEKSGTAEVSSILEERILGADTTADLEETGRVLSIGDGIARVYGLRNVQAEEMVEFSSGLKGMSLNLEPDNVGVVGLANDKLIKEGDIVKRTGAIVDVPVGDELLGRVVDALGNTIDGKGPIGSKTRRRVGLKAPGIIPRISVREPMQTGIKAVDSLVPIGRGQRELIIGDRQTGKTSIAIDTIINQKRFNDGTDEKKKLYCIYVAIGQKRLTDADAMKYTIVVSRTASDAAPLQYLAPYSGCSMGEYFRDNGTHALIIYDDLSKQAVAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKMNDHFGGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLETELFYKGIRPAINVGLSVSRVGSAAQTRAMKQVAGTMKLELAQYREVAAFAQFGSDLDAATQQLLNRGVRLTELLKQGQYVPMAIEEQVTVIYAGVRGHLDKMEPSKITKFESAFLAHVKSQHQELLATIRADGKISEQADAKLKEIVLNFLSTFEA
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Subunits alpha and beta form the catalytic core in F(1).  Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.  Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity).
What are the official names of this protein?
ATP synthase subunit alpha, mitochondrial, ATP synthase F1 subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SYA_HALH5
Sequence: MKYLTSAQVRQMFLDFFKEKGHDVEPSASLVPHDDPSLLWINSGVATLKKYFDGRVIPENPRITNAQKSIRTNDIENVGKTARHHTFFEMLGNFSIGDYFKEEAIEWAWEFLTSEKWIGFDKEKLSVTVHPEDDEAYSYWKEKIGIPEERIIRLEGNFWDIGEGPSGPNTEIFYDRGPEYGDQPNDPELYPGGENDRYLEVWNLVFSQFNHNPDGSYTPLPKKNIDTGMGLERMVSVIQNVPTNFETDLFMPIIRATEKISGTEYGSHHEADVSFKVIADHIRTVTFAIGDGALPSNEGRGYVLRRLLRRAVRYAKQIGIDRPFMYELVPVVGDIMVDFYPEVKEKAAFIQKVVKTEEERFHETLNEGLSILEKVIDKAKSEGASTISGSDVFRLYDTYGFPVDLTEEYVEEQGLQVDLDGFEAEMERQRERARTARQQAGSMQVQDEVLGQITVDSTFIGYKQLSTETTIETIVLDKTVADYVGAGQEAKVILKETPFYAESGGQVADKGIIRGANGFAVVSDVQKAPNGQHLHTVIVKEGTLQVNDQVQAIVEETERSGIVKNHTATHLLHRALKDVLGEHVNQAGSLVSEERLRFDFSHFGQVTDEEKEKIERIVNEKIWQAIKVNISTKTLDEAKAIGAMALFGEKYGDIVRVVEVGDYSIELCGGCHVTNTSEIGLFKIVSESGIGAGVRRIEAVTGKEAFLFMAKQLDLLKETAATVKAKNVKDVPVRVEALQQQIRELQRENESLNAKLGNMEAGSLVNEVQKIEGVPVLAKAISGADMDGLRSIVDKLKQEIPSVVIVLGTASEGKVNIVAGVTKDLINKGYHAGKLVKEVATRCGGGGGGRPDMAQAGGKQPEKLQDALSFVYEYVKSIS
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
Protein: OSK3_ORYSJ
Sequence: MDGNAKGGGHSEALKNYNLGRTLGIGSFGKVKIAEHKLTGHRVAIKILNRRQMRNMEMEEKAKREIKILRLFIHPHIIRLYEVIYTPTDIYVVMEYCKFGELFDYIVEKGRLQEDEARRIFQQIISGVEYCHRNMVVHRDLKPENLLLDSKYNVKLADFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSALARDLIPRMLVVDPMKRITIREIREHQWFQIRLPRYLAVPPPDTAQQAKMIDEDTLQDVVNLGYGKDHVCESLRNRLQNEATVAYYLLLDNRFRATSGYLGADYQESLERNFNRFASSESASSNTRHYLPGSSDPHASGLRPHYPVERKWALGLQSRAQPREIMIEVLKALQDLNVSWKKNGQYNMKCRWSVGTQATDMLDVNNSFVDDSIIMDNGDVNGRLPAVIKFEIQLYKTRDEKYLLDMQRVTGPQLLFLDFCADFLTKLRVL
What are the official names of this protein?
Serine/threonine protein kinase OSK3, OsK3, Serine/threonine protein kinase OSK35, OsK35.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL2_SYNP2
Sequence: MGIRSFRPYTPGTRQATVSDFSEITKSKPEKSLTKYKHRKKGRNNRGVITCRHRGGGHKRLYRLIDFRRDKRDITAQVTAIEYDPNRNARIALVQYEDGEKRYILQPAGLGVGDTIIAGEEAPYEIGNALPLYKIPLGTEIHNIELYAGRGGQMVRSAGAFAQLVAKEGDYVTIKLPSKEVRMVRKECYATIGKVGNAEARNLKLGKAGRTRHLGRRPQVRGSVMNPVDHPHGGGEGRAPIGRSGPVTPWGKPALGKKTRKKKKQSSSLIVRRRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: NPD_HELPY
Sequence: MKNLVILSGAGISAESGIKTFRDADGLWEGHDIMEVASPYGWKKNPQKVLDFYNQRRRQLFEVYPNKAHKALAELEKHYQVNIITQNVDDLHERAGSSRILHLHGELLSVRSEKDPNLVYRWEKDLNLGDLAKDKSQLRPDIVWFGEAVPLLKEAISLVKQAHLLIIIGTSLQVYPAASLYTHAHKDALIYYIDPKAKNAHLPQNVQCINESAVHAMQDLMPKLIEMAS
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PQQB_RHOPS
Sequence: MMRVVVLGAAAGGGVPQWNCGCSVCRAAFADRDLRRTQASMAVSADGDHWFLINASPDLRQQVIATPQLHPKPGALRHSPIAGVILTNGEVDAVAGLLSMREGSPFAIYAHAKVLAILKANSIFNVLNEKLVSRRPIETDQRFEPTLPDGTLSGLDVVAFSVPGKGAWYLEGQAHPGGDAADGDTLGLTITDKATGQSIHVLTACARVTDDLKARLAGAPLVLFDGTVWRDDELITAGLGHKTGQAMGHIAMSGDEGAIAALGDLDIARKLFVHINNSNPVLLSCSAEREAAERAGWQVPADGTEVTL
What is the function of this protein?
May be involved in the transport of PQQ or its precursor to the periplasm.
What are the official names of this protein?
Coenzyme PQQ synthesis protein B, Pyrroloquinoline quinone biosynthesis protein B.
What is the protein family that this protein belongs to?
Belongs to the PqqB family.
Protein: GLO16_ORYSJ
Sequence: MASKPGPLTQWPWHNLGNYKYALVAPSAAYSTYRFVTASSAAERDLLNFMVFPMLLLRLLYGQLWITVSRHQTARSKHKIVNKSLDFEQIDRERNWDDQIILTALVFYLVSATMPQAQVAPWWSTKGMVVTAVLHAGPVEFLYYWLHRALHHHWLYARYHSHHHASIVTEPITSVIHPFAEEVVYFVLLAIPILSTVATGTVSVVTANGYLVYIDFMNYLGHCNFELVPKCLFHVFPPLKYLLYTPSFHSLHHTQFRTNYSLFMPVYDYIYGTTDKSSDELYERTLQGRDEAAWRPDVVHLTHLTTPESVFHNRLGFAAVASNPLGAAASGHLLRAASAVASPLLSLFASTFRSEANRLDKLNIETWVIPRFTSHYTSKSDGYKVSRLIEKAVSDAEASGARVLTLGLLNQGYDLNRNGELYVVRKPSLKTKIVDGTSLAVAAVLNMIPQGTKDVLLLGNANKISLVLTLSLCKREIQVRMVNKELYECLKQQLQPEMQEHLVLSCSYSSKVWLVGDGVTDEEQMKAQKGSHFVPYSQFPPNKARNDCVYHCTPALLVPESFENLHVCENWLPRRVMSAWRAAGIVHALEKWDGHECGGRVTGVQKAWSAALARGFRPYDDHHHPGITHDGRGGL
What is the function of this protein?
Aldehyde decarbonylase involved in the conversion of aldehydes to alkanes.  Core component of a very-long-chain alkane synthesis complex.
What are the official names of this protein?
Very-long-chain aldehyde decarbonylase GL1-6, Protein GLOSSY 1-6.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: TIM9_DICDI
Sequence: MDRRLSKKEEERIVNELNKLQMIEMVDTSVNLTNKCFQSCITNFRIRKLDDEEQLCVYKCVEKNMFFTSALNNHFMKLSNEGMF
What is the function of this protein?
Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  The TIM22 complex forms a twin-pore translocase that uses the membrane potential as external driving force (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit Tim9.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: STOX_ARGME
Sequence: MIPNSSSSSILSLLVLLLFSTSSSWATNSIHEDFLNCLSIYKSSFPIPIYTSKNSSFNTLFRSSARNLRFLSPNSTQKPEFIITPTLESHVQTTVVCSKKHGLDLKVRSGGHDVEGLSYVSDSPYVMIDLVDFRNITVNVKNATAWIQAGSSLGEVYYKVGNESKNTLGFPAGFCPTVGVGGHISGGGFGSLVRKYGLASDQVIDARIVTVNGEILNKETMGKDLYWAIRGGGANNFGVLLSWKVKLVPVTPIVTVATIDRTLEQGATNLVHKWQFVADRLHEDVYIGLTMVTANTSRAGEKTVVAQFSFLFLGNTDRLLQIMEESFPELGLKRNDTTEMSWVESHVYFYRRGQPIEFLWDRDHLTKSFLKVKSDYVREPISKLGLEGIWKRYVGGDSPAMLWTPFGGRMNQISEFESPYPHRAGNIYNIMYVGNWLNENESEKQLNWMRSFYSYMGRYVSKNPRSAYLNYKDLDLGVNDNNVSEYIRYLKARSWGRKYFKNNFEKLVKVKSMVDPDNFFKNKQSIPPIRSWGKELEAINIVI
What is the function of this protein?
Catalyzes the oxidation of different tetrahydroprotoberberines, such as (S)-canadine, (S)-scoulerine and (S)-tetrahydropalmatine.
What are the official names of this protein?
Tetrahydroberberine oxidase, THB oxidase, (S)-tetrahydroprotoberberine oxidase, AmSTOX.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: PANE_SALTI
Sequence: MKITVLGCGALGQLWLSALCKHGHDVQGWLRVPQPYCSVNLIDTDGSFFNESLTANDPDFLAKSELLLVTLKAWQVSDAVRTLASTLPVTSPILLIHNGMGTIEELQSIQQPMLMGAITHAARRDGNIIIHVANGTTHIGPAREQDGDYSYLAEILQGVLPDVAWHNNIRAEMWRKLAVNCVINPLTALWNCPNGELRHHTDEINAICEEVAAVIEREGYHTSADDLCYYVEQVIDSTAENISSMLQDVRAMRHTEIDYITGYLLKRARVHGLAVPENSRLFEMVKRKESEYERSGTGMPRPW
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
What are the official names of this protein?
2-dehydropantoate 2-reductase, Ketopantoate reductase, KPR.
What is the protein family that this protein belongs to?
Belongs to the ketopantoate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A_ENCCU
Sequence: MVVIQGKGGKADPRVIGKDEEHQKSIVKLSQIKKIMKDRTRMRISKDALVAVSACVMYLISEITDGAKNVASTDGKKKVMPKHINNAICNDTELHFVGHDWLIKNGGMKSYIAPGDFAVSSKKGSSRD
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL34_TOBAC
Sequence: MVQRLTYRKRHSYATKSNQHRVVKTPGGKLIYQSTKKRASGPKCPVTGKRIQGIPHLRPTEYKRSRLSRNRRTVNRAYGGVLSGSAVRERIIRAFLVEEQKIVKKVLKIQKAKEKLAAKS
What are the official names of this protein?
60S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL34 family.
Protein: RL20_CLOBA
Sequence: MARVKRAKNARKNHKKVLKLAKGYYGGKSKLFKTANESVIRALRNSYVGRKNKKRDYRRLWIARINAATRINGLSYSKFMNGIKLAGIDINRKMLSEIAINDAKAFADLVEVAKKQLNA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: LDH_STRP8
Sequence: MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: K1C11_LAMFL
Sequence: MSFSSRSIGGYGGMSTRLGRGSASVYEGGGSSGGYRISQSSMGGGGGYGGGYGGGGGYRGGGGYGGGCAISSSFQSFGAFRGGGAGGGGLSGGNEKAEMQGLNDRLAEYIEKVRFLENANQELELRIKELLKGKGPGNKDYSAYYTTMQELRDKILAQIMENARVSLEIDNARLAADDFRSKWETELALRSSVEADINNLRGLLDEYSMARMGLEGEIESLREELIFMRKNHEEELAALRAQLEGSSMSVEVDSTKGKDLHKILAEVRAQYEAMIAKNRVDQEEAFNKQAQSVQVVAVQHSQASQAAKVEVTETRRAMQSLQAELDSLRGLIRSLEDQLQDTEERNARDLSTYTMQIQRLEGELSNLRHGINQQLKEYADLLNMKMKLEAEIATYRRLLEGEDSRMGNISANSTSGLITVSGGGGGGGGGVSGGGGGGGMSMTMTSSSSSGGGGGSSSSGGGSVVKTTTTKESSSYSTGYRS
What are the official names of this protein?
Keratin, type 1 cytoskeletal 11, Type I keratin 11.
What is the protein family that this protein belongs to?
Belongs to the intermediate filament family.
Protein: ATRA_ASPOR
Sequence: MASHKKSEDPLVVKDRQEQECESSDSTIASENASEHRSPMGLIDEDGIETLNRIASQSSRRRSSVYPPNVPTRTSTLATISENDPAVDPQGPSFDLNKWLKMVLRESERQGREAHRTGIVFKNFTVSGTGAALQLQDTVSSMLSAPFRIGEMMKNRHSPPKRILNEFNGLLKSGELLLVLGRPGSGCSTFLKSLCGELHGLSMSKESVIHYDGVPQQRMIKEFKGEVVYNQEVDKHFPHLTVGQTLEFAALARTPAQRIRDMSREEFAKHITQVVMAVFGLSHTYNTKVGNDFVRGVSGGERKRVSIAEMALAHSPLAAWDNSTRGLDSATALKFVEALRLFADLSGSAHAVAIYQASQSIYDIFNKVVVLYEGRQIYYGPAKDAKSYFERQGWECPQRQTTGDFLTSVTNPSERKARPGMENQVPRTAEDFEAYWRKSPEYQKLMSEISHYEQEHPLEEEGDALATFQQKKREIQAKHTRPQSPYLLSVPMQIKLNTKRAYQRVWNDISSTVSTVISQIIMALIIGSVFYGTPDATAGFTAKGATLFFAVLLNALIAMNEINSLYSQRPIVEKHNSYAFYHPATEAIAGVVSDIPVKFVIAVVFNLILYFLAGLHRSAGQFFLYLLVTFIVMFVMSAVFRTMAAITQTVSQAMGLAGILILALIVYTGFVLPVPSMHPWFEWIHYLNPIYYAFEMLIANEFHGRDFICSQFIPAYPNLSGNSFVCSSAGAKAGQRAISGDDYIQVNYQYSYGHVWRNFGILIAFLVGFMMIYFIATELNSSTSSTAEVLVFRRGHEPAYLRTDSKKPDAESAVELSAMKPTTESGEGDMSIIPPQKDIFTWRDVCYDIEIKGEPRRLLDHVSGWVKPGTLTALMGVSGAGKTTLLDVLAHRTSMGVITGDMFVNGRGLDQSFQRSTGYVQQQDLHLETATVRESLRFSALLRQPPNVSIQEKYDYVEDVIRMLKMEDFAEAVVGVPGQGLNVEQRKLLTIGVELAAKPKLLLFLDEPTSGLDSQSSWAICAFLRRLADSGQAVLCTIHQPSAILFQQFDQLLFLARGGKTVYFGPIGQNSNTLLNYFESNGARKCADDENPAEWMLEIVNAGTNSEGENWFDVWKRSSECQGVQTEIDRIHREQQSKTQASDKDNESWSKSEFAMPFWFQLYQVTYRVFQQYWRMPEYIASKWVLGILSGLFIGFSFFQAKSSLQGMQTIVYSLFMLCSIFSSLVQQVMPLFVTQRSLYEVRERPSKTYSWKAFLIANIIVEIPYQIMMGILTYACYYYAVVGVQDSERQGLVLLLCIQFFIYASTFAHMAIAAMPDTETASAIVVLLFAMSLTFCGVMQTPTALPGFWIFMYRVSPFTYWVSAMAATQLHDRVVQCSPSEMSIFDPPSGQTCGEYMSSFMSMAGGQLSNPNATSDCNYCSVAVADDFLSSVNIYWSERWRNFGLMWVYIVFNIFLATMLYYTFRVKKWNLSGLKERFSKKK
What is the function of this protein?
Pleiotropic ABC efflux transporter involved in the basal level of azole susceptibility (PubMed:30011258).  Confers resistance to miconazole and clotrimazole (PubMed:30011258).
What are the official names of this protein?
ABC multidrug transporter atrA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. PDR (TC 3.A.1.205) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVC_ECO5E
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: MDHM_FELCA
Sequence: MLSALARPAGAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNASIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFIAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDLPQDQLTAVTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAINGKEGVVECSFVKSQETDCPYFSTPLLLGKKGIEKNLGIGKISPFEEKMIAEALPELKASIKKGEEFVKNMK
What are the official names of this protein?
Malate dehydrogenase, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 1 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: SYF2_DEBHA
Sequence: MSSEESGEVGVPKNGNQDDDSGSTRVSVSDRLAKLQRLKRKKQESEKLNKQELFQDYKQQKLKSIEYKKIEQKKLNAELEQEKLDSIEKGEDFERKQNWDWTIEDCEKWEKKTKQKGRNQKSGFQNFNKMAEQAYNKELSNLKVDKETYDQQKNAINKNKSGNQSQMSKILPVSSKPSAADTNRLVRNIEEANNRRMKRRRNKDDENDVNSYINDKNKQFNLKLNRQYDES
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor SYF2.
What is the protein family that this protein belongs to?
Belongs to the SYF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPO11_METVS
Sequence: MSYINIIEKSENSIELELVNDDHSLSNALKESLLSKKGVVIASYGVEHPVLHPETGRYISNPTLVLKTEGVLAEKVLKEALRDIIDLCSNCLEEL
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit L.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPP5_TRIEQ
Sequence: MAAAKWLIASLAFASSGLAFTPEDFISAPRRGEAIPDPKGELAVFHVSKYNFDKKDRPSGWNLLNLKNGDISVLTTDSDISEITWLGDGTKIVYVNGTDSVKGGVGIWISDAKNFGNAYKAGSVNGAFSGLKLAKSGDKINFVGYGQSTTKGDLYNEAAAKEAVSSARIYDSLFVRHWDTYVGTQFNAVFSGALTKSGDKYSFDGKLKNLVHPVKYAESPYPPFGGSGDYDLSSDGKTVAFMSKAPELPKANLTTTYIFVVPHDGSRVAEPINKRNGPRTPQAIEGASSSPVFSPDGKRIAYLQMATKNYESDRRVIHIAEVGSNKPVQRIASNWDRSPEVVKWSSDGRTLYVTAEDHATGKLFTLPADARDSHKPAVVKHDGSVSSFYFVGSSKSVLISGNSLWSNALFQVATPGRPNRKLFYANEHDPELKGLGPNDIEPLWVDGARTKIHSWIVKPTGFDKNKVYPLAFLIHGGPQGSWGDSWSTRWNPRVWADQGYVVVAPNPTGSTGFGQKLTDDITNDWGGAPYKDLVKIWEHVRDHIKYIDTDNGIAAGASFGGFMVNWIQGHDLGRKFKALVSHDGTFVGSSKIGTDELFFIEHDFNGTFFEARQNYDRWDCSKPELVAKWSTPQLVIHNDFDFRLSVAEGVGLFNVLQEKGIPSRFLNFPDETHWVTKPENSLVWHQQVLGWINKWSGINKSNPKSIKLSDCPIEVVDHEAHSYFDY
What is the function of this protein?
Extracellular dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini.  Contributes to pathogenicity (By similarity).
What are the official names of this protein?
Dipeptidyl-peptidase 5, Dipeptidyl-peptidase V, DPP V, DppV.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Secreted.