PharMolix/UniProtQA huggingface dataset:
Protein: ZC12D_HUMAN
Sequence: MEHPSKMEFFQKLGYDREDVLRVLGKLGEGALVNDVLQELIRTGSRPGALEHPAAPRLVPRGSCGVPDSAQRGPGTALEEDFRTLASSLRPIVIDGSNVAMSHGNKETFSCRGIKLAVDWFRDRGHTYIKVFVPSWRKDPPRADTPIREQHVLAELERQAVLVYTPSRKVHGKRLVCYDDRYIVKVAYEQDGVIVSNDNYRDLQSENPEWKWFIEQRLLMFSFVNDRFMPPDDPLGRHGPSLSNFLSRKPKPPEPSWQHCPYGKKCTYGIKCKFYHPERPHHAQLAVADELRAKTGARPGAGAEEQRPPRAPGGSAGARAAPREPFAHSLPPARGSPDLAALRGSFSRLAFSDDLGPLGPPLPVPACSLTPRLGGPDWVSAGGRVPGPLSLPSPESQFSPGDLPPPPGLQLQPRGEHRPRDLHGDLLSPRRPPDDPWARPPRSDRFPGRSVWAEPAWGDGATGGLSVYATEDDEGDARARARIALYSVFPRDQVDRVMAAFPELSDLARLILLVQRCQSAGAPLGKP
What is the function of this protein?
May regulate cell growth likely by suppressing RB1 phosphorylation (PubMed:19531561).  May function as RNase and regulate the levels of target RNA species (Potential).  In association with ZC3H12A enhances the degradation of interleukin IL-6 mRNA level in activated macrophages (PubMed:26134560).  Serve as a tumor suppressor in certain leukemia cells (PubMed:17210687).  Overexpression inhibits the G1 to S phase progression through suppression of RB1 phosphorylation (PubMed:19531561).
What are the official names of this protein?
Probable ribonuclease ZC3H12D, MCP-induced protein 4, Transformed follicular lymphoma, Zinc finger CCCH domain-containing protein 12D, p34.
What is the protein family that this protein belongs to?
Belongs to the ZC3H12 family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Note=Colocalizes with ZC3H12A in GW bodies (GWBs) (PubMed:26134560). SUBCELLULAR LOCATION: [Isoform 1]: Cytoplasm. Note=Localized as discrete granules. Colocalized with mRNA-processing body markers, AGO2 and DCP1A, but not with a stress granule maker, TIA1, in the cytoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Cytoplasm. Nucleus.
Protein: SPIT4_HUMAN
Sequence: MKSAKLGFLLRFFIFCSLNTLLLGGVNKIAEKICGDLKDPCKLDMNFGSCYEVHFRYFYNRTSKRCETFVFSGCNGNLNNFKLKIEREVACVAKYKPPR
What are the official names of this protein?
Kunitz-type protease inhibitor 4.
What are the subcellular locations of this protein?
Secreted.
Protein: FABD_SALTY
Sequence: MTQFAFVFPGQGSQSVGMLAEMAANYPIVEETFAEASAALGYDLWALTQQGPAEELNKTWQTQPALLTASVALWRVWQQQGGKMPALMAGHSLGEYSALVCAGVINFADAVRLVEMRGKFMQEAVPEGTGGMSAIIGLDDASIAKACEESAEGQVVSPVNFNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAKITFSAPTVPVVNNVDVKCETDAAAIRDALVRQLYNPVQWTKSVEFIAAQGVEHLYEVGPGKVLTGLTKRIVDTLTASALNEPAALSAALTQ
What are the official names of this protein?
Malonyl CoA-acyl carrier protein transacylase, MCT.
What is the protein family that this protein belongs to?
Belongs to the FabD family.
Protein: PSBT_THEVL
Sequence: METITYVFIFACIIALFFFAIFFREPPRITKK
What is the function of this protein?
Seems to play a role in the dimerization of photosystem II (PSII).  PSII is a light-driven water plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T, PSII-Tc.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: ALR_FRATF
Sequence: MNILKISKQTLRNNIKIIREYIGNAKMCFPVKANAYGHGIEDIVENTHDLVDFFAVANSLEAFRVTAVAKNPVLVFGVIYYEYIEKMISENIRVSIQDYEYIEKLEQIAKELDKKVYAHININTGMNRMGVDYNDACRTIQRAYESDWLILEGVYSHLACADNRDHPTNIKQKNRFDSIVKFTKGLSQDIICHLSNSYGFLGQKGICYDMVRPGILSYGFLPEFYVDRVIREIKPIARLLSKVVKIITLQEGEGVGYSLIYRGFEGEQLAVIPIGYGDGFPRELGDRGFVNINDVMYPMAGRMSMDGLTVSLGINEYDVKVGDTVELISAIPRNRNSAFSIAKQTNTIEYDIMSTLNNRIIRKII
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: ATPB2_DROME
Sequence: MPTITEDCIDGFQQYYSRPPERPKKKSLKQMVYDSEDNSYFGRSMDSWAKIGIFYVAFYGVLAALVAICMWAFFQTLDPRIPKWTLDRSLIGTNPGLGFRPLPPVDNVESTLIWYKGTQHENYKHWTDSLDDFLAVYKVPGLTPGRGQNIYNCDYNQPPPKGQVCDVDIKTWSPCTKENNYSYHKSAPCIFLKLNKIYGWIPEYYNRSNDLPANMPASLKTYIAEVEKTQPEKLNTIWVSCEGENPADQENIGAVNYLPIRGFPGYFYPYQNSEGYLSPLVAVHFQRPKRGIIINVECRAWARNIIHDRKERIGSVHYELLID
What is the function of this protein?
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.  The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
What are the official names of this protein?
Sodium/potassium-transporting ATPase subunit beta-2, Protein nervana 2, Sodium/potassium-dependent ATPase subunit beta-2.
What is the protein family that this protein belongs to?
Belongs to the X(+)/potassium ATPases subunit beta family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein.
Protein: MTBP_BPPHT
Sequence: MSKLRVMSLFSGIGAFEAALRNIGVDYELIGFSEIDKYAIKSYCAIHNVSETLNVGDISKAKKDNIPYFDLLTSGFPCPTFSVAGGRDGMEYKCSNCSHEHLITYEDYKKGVKCPKCEAVSKAKDERGTLFFETALLAEEKKPKFVILENVKGLINSGNGQVLRIISETMNNIGYRIDLELLNSKFFNVPQNRERVYIIGIREDLVENEQWVVGQKRNDVLSKGKKRLQEINIKSFNFKWPLQDTVTKRLREILEDFVDEKYYLNEEKTKKLVEQLGTAPLQKQEVREPLMVGHVDLKGHDAIKRVYSPEGLSPTLTTMGGGHREPKIAEKQKEVRAVLTPEREEKRQNGRRFKENGEPAFTVNTIDRHGVAIGEYPKYKIRKLSPLECWRLQAFDDEDFEKAFAAGISNSQLYKQAGNSITVSVLESIFQELIHTYVNKESE
What is the function of this protein?
A methyltransferase that methylates C-1 within the sequences 5'-GGCC-3' and 5'-GCNGC-3' (PubMed:12654995).  Modification confers resistance against restriction enzymes that recognize these sequences (Probable).
What are the official names of this protein?
Orphan methyltransferase M.Phi3TI, M.Phi3TI, Cytosine-specific methyltransferase Phi3TI, Modification methylase Phi3TI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: NAC67_ORYSJ
Sequence: MAAAKRRVRDAEADLNLPPGFRFHPTDEELVAHYLCPRAAGRAAPVPIIAELDLYRHDPWDLPHRALFGRREWYFFTPRDRKYPNGSRPNRAAASGYWKATGADKPVLHNGRTAGIKKALVFYHGKPPRGVKTEWIMHEYRLAKKGGAAAAAGAGALRLDDWVLCRLYNKKNEWEKMQSRKEEEEAMAAAQSWGETRTPESEVVDSDAFPEMDYSLPAASFDDALLPKEEARDDDWLMGMSLDDLQGLGSLLQADDLSMLAPPPAAKTEPLGAPFF
What is the function of this protein?
Probable transcription factor involved in stress response.
What are the official names of this protein?
NAC domain-containing protein 67, ONAC067, OsNAC3.
What are the subcellular locations of this protein?
Nucleus.
Protein: TRUA_SALTI
Sequence: MSGQQSSPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPINVFCAGRTDAGVHGTGQVVHFETTALRKDAAWTLGVNANLPGDIAVRWVKTVPDDFHARFSATARRYRYIIYNHRLRPAVLAKGVTHYYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLLEVGAHNQPESWIAELLAARDRTLAAATAKAEGLYLVAVDYPDRFDLPKPPMGPLFLAD
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MUG_SALPB
Sequence: MVKDILAPGLRVVFCGINPGLSSANTGFPFAHPANRFWKVIHLAGFSDRQLKPEEAEKLLDFRCGVTKLVDRPTVQATEVKLHELRSGGRNLIDKIEDYQPAALAVLGKQAFEQGFSQRGIAWGKQKIAIGATMVWVLPNPSGLNRIKTEKLVEAYRELDQALIMRGL
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3604_ALIF1
Sequence: MRIFSETEIRIIGCLIEKEITTPEQYPLTLNALTTACNQKSNRDPVTSLTDSDVLDSVNTLIQERIITDETRGNSRVAKYQHRFCNTEFGSLKLSKQELAVLCVLFLRGPQTPGELRTRTQRLCEFDNVAQVENVLNGLSADEHSPKVIKLAKEPGKREARFAHLFCGEVSQAIATVQQAPSESHDNERIVALESDVADLKLEVEELKKLINNLLDK
What are the official names of this protein?
UPF0502 protein VF_A0604.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: RS2_STRPB
Sequence: MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQQTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLTNWGTIQKRIARLKEIKRMEEEGTFDVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDVMYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDIIIPANDDAIRAVKLITAKLADAIIEGRQGEDADVAFEADTQADSIEEIVEVVEGDNA
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: MEPE_RAT
Sequence: MQAVSVGLFLFSMTWAAPKLNEDGSSGGNQGNIHLASVKPEPMVGKGTEGGRDAPLHLLDQNRQGATLLRNITQPVKSLVTGTEVQSDRNKEKKPQSVLSVIPTDVHNTNDYSEDTENQQRDLLLQNSPGQSKHTPRARRSTHYLTHLPQIRKILSDFEDSASPDLLVRGDNDVPPFSGDGQHFMHTPDRGGAVGSDPESSAGHPVSGSSNVEIVDPHTNGLGSNEIPGREGHIGGAYATRGKTAQGAGSADVSLVEGSNEITGSTKFRELPGKEGNRVDASSQNAHQGKVEFHYPQAPSKEKVKGGSREHTGKAGYNEIPKSSKGGASKDAEESKGNQVTLTESQRFPGKGKGQSSHSLGNEVKSEEDSSNSLSREGIAIAHRRTSHPTRNRGMSQRRGSWASRRPHPHRRVSTRQRDSSESSSSGSSSESSGD
What is the function of this protein?
Regulates renal phosphate excretion (By similarity).  Regulates bone mineralization by osteoblasts and cartilage mineralization by chondrocytes (By similarity).  Regulates the mineralization of the extracellular matrix of the craniofacial complex, such as teeth, bone and cartilage (By similarity).  Increases dental pulp stem cell proliferation.
What are the official names of this protein?
Matrix extracellular phosphoglycoprotein, Osteoblast/osteocyte factor 45, OF45, Osteoregulin.
What is the protein family that this protein belongs to?
Belongs to the PF07175/osteoregulin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: HUTH_BURCJ
Sequence: MITLTPGHLTLPQLRQIARESVQLKLDPASFAKIDAGAKAVADIAAKGEPAYGINTGFGRLASTHIPHDQLELLQKNLVLSHAVGVGEPMARSSVRLLMALKLSSLGRGHSGIRREVMDALITLFNADVLPLIPVKGSVGASGDLAPLAHMSAVLLGVGEVFIRGERASALDGLRVAGLAPLTLQAKEGLALLNGTQASTALALDNMFAIEDLYRTALVAGALSVDAAAGSVKPFDARIHELRGHQGQIDAAASYRELLEGSPINQSHRDCDKVQDPYSLRCQPQVMGACLDQMRHAADVLLVEANAVSDNPLIFPDTGEVLSGGNFHAEPVAFAADNLALAASEIGALAERRIALLIDATLSGLPPFLVKDGGVNSGFMIAHVTAAALASENKTLAHPASVDSLPTSANQEDHVSMATFAARKLADIADNTKHILAIELLAAAQGVDLRAPYHTSPKLAPVMETIRSQVAHYELDHYFAPDIAVIAKLVGERAFAKVAPFSFASEQ
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT23_YEAST
Sequence: MMSGTGNVSSMLHSYSANIQHNDGSPDLDLLESELLDIALLNSGSSLQDPGLLSLNQEKMITAGTTTPGKEDEGELRDDIASLQGLLDRHVQFGRKLPLRTPYANPLDFININPQSLPLSLEIIGLPKVSRVETQMKLSFRIRNAHARKNFFIHLPSDCIAKDKFFTSSDDPTNLTIPNRDINERTLFLDAFLLCASNNNSNNFKQTYVCNRCINREKRRASRRKSGLNDNSIWQNNENKRAIIFNSKQLFIISNNGLSGNSNCINFDLPTRIVCYCRHHKATNGFVVLFLLRDHNGDILAKTITDPIMIMDKKNASNTTTPTSTSNAQVSPMTNDTRSFSSPQSDLNFPSEFPLPSNSKNFVISTNCMLDSNCNNNNNDNDNKNNIKTNTAMMNNNRHFPSPNSSSEDSNHSFSDIHFSNNNDNNLHRSLDSWSSTGFNSSSNPALTTLTSDFSAASARHTGKRQRSVNEPFMSTPNTFSRLPQKFIDSSKDISNHNSVPVALNNKPSIQRVIPAQGSINGGIEVTLLGSKFKQGLIIKFGENIALSSQCWNESTMVTYLPPSSKPGPVLVTIVDPSETSMRNNSNSSVSTSNSTNDILHLNKYTGEKAIFTYVDDTDRQLIELALQIVGLKMNGKLEDARNIAKRIVGSDSSPSNNNAGLHSQNSSLNSYTNMMRNINDEQLITEVIKSFKRNNNLSTVNLSMCDVRGRTLLHLAAFNNWYSLVSLLIKYGSHLNDQDLFGFTPLHMACINGDLRIIRLLLECNVNIMKKTRNGFIAKQFFLMNYTVNKTRYSNYETSLFDDILTRLTKNTTGSSDTQPFERNVSQSSFNSSLFDDDDADHDYVQERKYLLADSAALAPEQSNCNDNTSFSILDSDSGYDISDCESSSDEIALEFFNTHKIKDFSSKPNEIPKTTKTSIEPDGSLWNRMLTRLNDELPKYEDLFPKKPKNWELGSKSVEIGPDNSAQMTVDDSQTSSEDDELEALQVGFNTIFSKKQNFQNDKMLLFFWIPLTLVLLLCFTLSNLGKDDDMFHNLSKIVQEYLRIGLAKVLLGNERMKTSFKMQLSKFQNNNILNDMRVN
What is the function of this protein?
Dosage-dependent suppressor of Ty-induced promoter mutations.  May exert its suppression effect through protein-protein interactions since does not present any of the motifs generally found in transcriptional activators or DNA binding proteins.
What are the official names of this protein?
Protein SPT23.
Protein: QUEA_ALKMQ
Sequence: MKTNEFDFDLPDRLIAQTPLEKRDHSRLMVLDKNKQEIVHKHFYDITDYLNPGDCLVINNTRVLPARLFGVKENTGGKMEFLLLKRIDLNTWEVLVKPGKKAKIGSRFEFGEGILKAEVLSMADEGARIVRFEYEGVFEELLDQLGKMPLPPYITEELADRERYQTVYSKHEGSSAAPTAGLHFTPELLSEIKKKGINVVSITLHVGLGTFRPVKVDSLENHEMHAEYYEITEEAAQVINDTKKAGNRVFAVGTTSCRTLESASTEKGKIEANKGWTNIFIFPGYQFKILDGLITNFHLPESTLIMLVSALLGKEKTLQAYKVAVDEQYRFFSFGDAMLIV
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_ECOLC
Sequence: MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPWLRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPP_SHIDS
Sequence: MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_NEOFR
Sequence: MAITKVHARQIFDSRGNPTVEVEVTTDKGLFRAAVPSGASTGVHEALELRDGIKADYVGKGVLKAVENVNKTIAPALVAANLDVKNQKAVDDFLLKLDGTPNKSKLGANAILGVSLAVARAGAADKGVPLYQHLGELAGNKGPWILPVPSMNVLNGGSHAGNKLAMQEFMILPTGAKSFTEALKMGSEVYHALKSVIKAKYGQDACNVGDEGGFAPNIQDNKEGLELLNEAIAKAGYTGKVKIGMDVASSEFYKDGKYDLDFKNPNSDPSKWISGEELGQFYKEITSEYPIVSIEDPYDQDDFESWSKFRADMQDKIQIVGDDLTVTNPKRIAMAIEKKACNGLLLKVNQIGTVSESIQAALDAFNDGWGVMVSHRSGETEDTFIADLVVGLKSGQIKTGAPCRSERLAKYNQLLRIEEELGANATYAGENFRRPF
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_PARPJ
Sequence: MNQPKSAPNSTDSAQGLSYRDAGVDIDAGDALVDAIKPFAKKTMRDGVLGGIGGFGALFEVPKKYKEPVLVSGTDGVGTKLRLAFQLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVGTAATVVKGIAHGCELSGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGSTIAPGDVVLGLASSGIHSNGFSLVRKIIERAQPDLNADFDGRSLADALMAPTHIYVKPLLALMQQIAVKGMAHITGGGLVENIPRVLREGLTAELDHRGWPLPPLFSWLQKHGGVADAEMHRVFNCGIGMAVVVSAADADAAIGLLSAAGEQVWKIGVIRESAAGEAQTVVV
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_DEHMC
Sequence: MSKFIFVTGGVVSSVGKGITVASLGNILKSRGLSVSVQKLDPYLNVDPGTMSPYQHGEVFVTQDGAETDLDLGSYERFIDIELTADSTVTSGQVYSEVINKERRGDYLGGTIQVVPHVTQEIKARIQRLADRSKADVVIVEVGGTVGDIEGQPFLEAIRQMRNDTGRDNVLYIHVTLLPYIQSTQELKTKPTQHSVNELRRIGIQPDIIVCRADYPISEGIRDKISLFCDVERKAVIFMPTVSTIYEVPLKLESEGVGDLLVSRLHLNASPSDLSVWRGLVEKIKEPTPTVRIALVGKYVELKDAYYSVRESLCHAAIHNGRDIQIDWVHAEDIEKNGPEEYLKHVQGIIIPGGFGIRGIEGMISAVKYARENGIPYLGLCLGMQVMVIEFARYVLGSDKAHSTEFEPDSPYPVIDLLPEQRGVDSKGGTMRLGNYPCVIQPGTMAGQAYGNNLINERHRHRFEFNNDYRDTLSKAGMLFSGLSPDGKLVEICEVTGHPFMMGSQFHPEFLSRPNRPHPLFREFINAAKKVIRDGEQPSLPLSP
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ATPL_ALKCK
Sequence: MTELAIGIAAGLAAIGGAIGVAIIVKAVIEGTARQPEQRGTLQTLMFIGAPLAEAVPIIAIVIAFLLFFMG
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ENGB_RICB8
Sequence: MTDEKVINKKLVGDNKLFRHQAKFVAGAMDIKQLPNFALPQIAFVGKSNVGKSSLINTICNNKKLAKVSNTPGRTRQINFFNLVDKLIIVDLPGYGFAQVPNQVKDQWEILINHYLRKSDNLKLVNLLIDSRRGIKENDKKVAELLLANKRDFQIIFTKSDKVTDRKNLNLEAQNFLATLNYSCNLIYVSSRSKEGARELKTSLAKCIKLEK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NODAL_XENTR
Sequence: MAFLTAVLCFGFACMVQGVPSWLESRIPLLGSSVASKHPSLLDGNRHHRDMKYPFYMMQLYQNLVMANDTGLARGHNTATKEYDTVLSLFAKRCMESEKRWTLSFDMSAVSKSSELKLAELRIQLPHIEMSHNVTVDVYHTRDGEENLYLGSFEANPFSTKGSPWKVFNVTRILQHYFKEGQDIKSEYLRTKDRAERGSGMSSAEFLDSPGDSPQYNPHHTPLRRYLSTEGVMLVLFTKVKPSVNHIGFPSLIKTAESSKYVDMEKASRMPGIRRHRRNKNEKHHLSMGSIPSRHVDNGKPLCRRVDMIVNFEDIGWGNWIVYPKKYNAYRCEGACPIPLNETFKPTNHAYMKSVVKLYQPEKVECPLCVPIKMSPLSMLYYEGDEVVLRHHQEMIVEECGCS
What is the function of this protein?
Cooperation and regulatory loops of multiple nodals are essential for mesendoderm patterning in early embryos.  Essential for mesoderm formation and axial patterning during embryonic development.  Activates the activin-like signaling pathway to induce dorsal and ventral mesoderm in animal cap ectoderm.  In addition, also dorsalizes ventral marginal zone (VMZ) tissues during gastrulation.  Acts in a downstream signaling cascade via cripto and cer1 to mediate cardiogenesis in embryonic mesoderm.  Directs the orientation of the left-right axis by driving the left-specific gene cascade in the left lateral plate mesoderm (By similarity).
What are the official names of this protein?
Nodal homolog, Nodal-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: D6KL3_ARATH
Sequence: MDSSSSVVYVGSSSKSRNFQSKSKGSITSFSIDSRGTKKSMKTLLIPEPEPTSPEVIESSVSSVSAESETPISIIRKKKQSEPRFYSSPTNTFYTEAKQSFTNTEFSECASISTIGIGGIDLEKNGVMIYRGSIGSDVSDESSSSGLSNAAYKPHRDNNDKRWVAIQEVRSRVGSSLEAKDFKLIKKLGGGDIGNVYLAELIGTGVSFAVKVMEKAAIAARKKLVRAQTEKEILQSLDHPFLPTLYSHFETEMNSCLVMEFCPGGDLHSLRQKQRGKYFPEQAARFYVAEVLLAMEYLHMLGIIYRDLKPENVLVREDGHIMLSDFDLSLRCAVSPTLVRFAAITLESKSSSYCIQPTCVDQSSCIVQPDCIQPVCFTPRFLSKGKHRKKSNDMSRQIRPLPELIAEPTSARSMSFVGTHEYLAPEIIKGEGHGSAVDWWTFGIFLYELLFGITPFRGGDNRATLFNVVGQPLRFPEHPNVSFAARDLIRGLLVKEPQHRLAYRRGATEIKQHPFFQSVNWALIRCTSPPQIPQPVKPMDQAHSVRHGFSQGHGHVGYDKPPTVDVKPSGNYLEIDFF
What is the function of this protein?
Protein kinase that regulates the auxin transport activity of PIN auxin efflux facilitators by direct phosphorylation.  D6PK-mediated PIN phosphorylation promotes auxin transport in the hypocotyl and this is a prerequisite for PHOT1-dependent hypocotyl bending.
What are the official names of this protein?
Serine/threonine-protein kinase D6PKL3, D6 protein kinase-like 3, Serine/threonine-protein kinase AtPK7.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Colocalizes with PIN1 to the basal (lower) membrane of root cells.
Protein: EFTS_THIDA
Sequence: MAEITASMVKDLREKTDAPMMDCKKALTEAGGDMQKAEEILRVRFGNKAAKSAGRVAAEGVVTIAISPDGKSAAMVEVNCETDFVAKNDDFLALSAALAEMVLTQKPADVAALSALPYKNSTVEGFRTELVGKIGENMSVRRFVRLDGQGKFASYIHGGKIGVLVDVTGDEAIAKDIAMHIAASKPKSLDASGVPQDLLDTERRVAIEKAKEAGKPEAMLEKIAEGTVQKFLKEVTLLSQPFVKDDKQTVEQVLKSKNSQCHGFTMYVVGEGIEKKVSDFAAEVAAAAKV
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_BUGCA
Sequence: MAPNLRKSHPLLKMINNSLIDLPTPSNISAWWNFGSLLGICLATQILTGLLLAAHYTADTTLAFSSVAHTCRNVQHGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLYKETWNTGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAVPYIGQTLVEWAWGGFSVDNPTLTRFFTLHFLLPFMIMGLTLIHLTFLHESGSNNPLGIVSNCDKIPFHPYFSLKDILGFMLMLLPLMTLALFSPNLLGDPENFTPANPLVTPPHIKPEWYFLFAYAVLRSIPNKLGGVLALAASVLILFLAPLLHKSKQRTMTFRPFSQLLFWTLTANVLILTWVGSQPVERPFIIIGQLASLTYFTILLILFPIIGALENKMLNY
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.