PharMolix/UniProtQA huggingface dataset:
Protein: GLNA_PANAR
Sequence: MNQGANKTVLDRYLRLDIPDQKCQAMYIWVDGTGENLRSKTRTLNFTPKSPSELPIWNFDGSSTGQAERSNSDVYLYPVAVYRDPFRLGNNKLVLCETYKYNKKPADTNQRWKCMEVMTRAADQHPWFGMEQEYTLLDIDKHPLGWPKNGYPGPQGPYYCGVGANRVYGRDVVEAHYRACLCAGINISGENAKVMPAQWEFQVGPCEGITMGDDLWMARYLLHRVAEDFDVVVTLDPKPIPGDWNGAGMHTNFSTEAMRGPNGILEIESAIDKLSKVHEKHIKAYDPHAGKDNERRLTGHYETSSIHDFSAGVANRGASIRIPRGVAEEKTGYLEDRRPSSNADPYVVSERLVRTICLNEQ
What is the function of this protein?
Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine.
What are the official names of this protein?
Glutamine synthetase, Glutamate--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the glutamine synthetase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Microsome. Mitochondrion.
Protein: DER_HAEIN
Sequence: MATPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGHAHIAGYDFIVIDTGGIDGTEEGVEEKMAEQSLLAIDEADIVLFLVDARAGLTAADIGIANYLRQRQNKITVVVANKTDGIDADSHCAEFYQLGLGEIEQIAASQGRGVTQLMEQVLAPFAEKMENADENDRTSEEEQDEWEQEFDFDSEEDTALIDDALDEELEEEQDKNIKIAIVGRPNVGKSTLTNRILGEDRVVVFDMPGTTRDSIYIPMERDGQQYTLIDTAGVRKRGKVHLAVEKFSVIKTLQAIQDANVVLLTIDARENISDQDLSLLGFILNAGRSLVIVVNKWDGLDQDVKDRVKSELDRRLDFIDFARVHFISALHGSGVGNLFDSIKEAYACATQKMTTSLLTRILQMATDEHQPPMIGGRRIKLKYAHPGGYNPPIIVVHGNQMDKLPDSYKRYLSNYYRKSLKIIGSPIRLLFQEGSNPFAGRKNKLTPNQLRKRKRLMKFIKKAKR
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RIMM_MYCBO
Sequence: MELVVGRVVKSHGVTGEVVVEIRTDDPADRFAPGTRLRAKGPFDGGAEGSAVSYVIESVRQHGGRLLVRLAGVADRDAADALRGSLFVIDADDLPPIDEPDTYYDHQLVGLMVQTATGEGVGVVTEVVHTAAGELLAVKRDSDEVLVPFVRAIVTSVSLDDGIVEIDPPHGLLNLE
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACG_LACLL
Sequence: MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWYTAEPASDFYHKYPVDLELAEEYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHKLFAECHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFIDYAAFCFEEFPEVNYWTTFNEIGPIGDGQYLVGKFPPGIKYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHALPTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDLRDEDFQALDAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRRVAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDDGRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERYPKKSAHWYKKLAETQVIE
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: OPSG_RAT
Sequence: MAQQLTGEQTLDHYEDSTQASIFTYTNSNSTRGPFEGPNYHIAPRWVYHLTSTWMILVVIASVFTNGLVLAATMRFKKLRHPLNWILVNLAVADLAETIIASTISVVNQIYGYFVLGHPLCVIEGYIVSLCGITGLWSLAIISWERWLVVCKPFGNVRFDAKLATVGIVFSWVWAAVWTAPPIFGWSRYWPYGLKTSCGPDVFSGTSYPGVQSYMMVLMVTCCIFPLSIIVLCYLQVWLAIRAVAKQQKESESTQKAEKEVTRMVVVMVFAYCLCWGPYTFFACFATAHPGYAFHPLVASLPSYFAKSATIYNPIIYVFMNRQFRNCILQLFGKKVDDSSELSSTSKTEVSSVSSVSPA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.  May increase spectral sensitivity in dim light.
What are the official names of this protein?
Medium-wave-sensitive opsin 1, Green cone photoreceptor pigment, Green-sensitive opsin, Medium wavelength-sensitive cone opsin.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL33_ACISJ
Sequence: MASKGGREKIKLVSTAETGHFYTTTKNKKTMPEKMSIIKFDPKARKHVEYKEAKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: ECTB_NOCFA
Sequence: MITAETNVFESLESNVRGYCRNWPTVFTTAKGAWLQDEDGKDYLDFFAGAGALNYGHNNPVLKQPLIDYIASDGITHGLDMSTAAKRKLLETLRDTVFAPRGLDYKVQFPGPTGANAVEAALKLARKVTGRETVLSFTNAFHGMTLGALSVTGNAAKRAGAGVPLVHAAHMPYDGYFDNTTADFQWMERVLDDTSSGFDRPAAVIVETVQGEGGINVARVEWLQHLAQLCAEREILLIVDDVQMGCGRTGPFFSFEVAGITPDIVTLSKSIGGYGLPLALVLFKPELDQWAPGEHNGTFRGNNPAFVTAQVALETFWSDGALEAATKAKGEKVATELATVAGHFPGLSTRGRGLVHGIAFEDPSQAGKVCQVAFERGLLVETSGSSDEVVKLLPPLTITDDELDQGLQILTGAIDTVCTGWGRLHHRAPAEGGERR
What is the function of this protein?
Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate.
What are the official names of this protein?
Diaminobutyrate--2-oxoglutarate transaminase, DABA aminotransferase, Diaminobutyrate--2-oxoglutarate aminotransferase, L-2,4-diaminobutyric acid transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
Protein: HBB_LUTLU
Sequence: VHLTGEEKAAVTSLWGKVNVDEVGGEALGRLLVVYPWTQRFFDSFGDLSSPDAVMGNPKVKAHGKKVLNSFSEGLKNLDNLKGTFAKLSELHCDKLHVDPENFKLLGNVLVCVLAHHFGKEFTPQVQAAYQKVVAGVANALAHKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: EX7L_SALA4
Sequence: MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAKLHSEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANARGECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEIVSRNQQELLRRIQSAQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALERLRQRMGFALEARIKQATQRQQRVSQRLSQQNPQPRIHRAQSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLATLARGYTVSTTTNGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_STRPI
Sequence: MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSRELQSFYANLENVSLEELAFWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHDSESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKAVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: THIE_ENT38
Sequence: MYQPDFPPVPFRLGLYPVVDSVVWIERLLQAGVKTLQLRIKDKCDEDVEPDVANAIKLGRRYGARLFINDYWQLAIQHQAYGVHLGQEDLETTDLSAIRNAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLTRHIERLADYPTVAIGGISLERVPAVLKTGVGSVAVVSAITQAADWQVATAQLLQLAGAGDE
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: PPT1_ARATH
Sequence: MQSSAVFSLSPSLPLLKPRRLSLRHHPITTAASSSDLNVSPNVVSIPSLSRRSWRLASSDSPLRAWSGVPSPISHSLDTNRFRTAATAVPESAEEGDNSGKLTKVLELGLLFAMWYLFNIYFNIYNKQVLKALHAPMTVTLVQFAVGSVLITIMWVLNLYKRPKISGAQLAAILPLAVVHTLGNLFTNMSLGKVSVSFTHTIKAMEPFFSVLLSAMFLGEKPTPWVLGAIVPIVGGVALASISEVSFNWAGFSSAMASNLTNQSRNVLSKKVMVKKDDSLDNITLFSIITLMSLVLMAPVTFFTEGIKFTPSYIQSAGVNVKQIYTKSLIAALCFHAYQQVSYMILARVSPVTHSVGNCVKRVVVIVSSVIFFKTPVSPVNAFGTGIALAGVFLYSRVKGIKPKPKTA
What is the function of this protein?
Phosphoenolpyruvate/phosphate translocator that transports phosphoenolpyruvate (PEP), 2-phosphoglycerate, 3-phosphoglycerate and dihydroxyacetone phosphate.  Imports PEP to the chloroplast stroma as one substrate of the shikimate pathway, from which aromatic amino acids and a variety of secondary products derive.  Required for correct leaf mesophyll cell development and expression of chlorophyll a/b binding protein 3 (CAB3).
What are the official names of this protein?
Phosphoenolpyruvate/phosphate translocator 1, chloroplastic, AtPPT1, Protein CAB UNDEREXPRESSED 1.
What is the protein family that this protein belongs to?
Belongs to the TPT transporter family. PPT (TC 2.A.7.9) subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast membrane; Multi-pass membrane protein.
Protein: CBX2_MOUSE
Sequence: MEELSSVGEQVFAAECILSKRLRKGKLEYLVKWRGWSSKHNSWEPEENILDPRLLLAFQKKEHEKEVQNRKRGKRPRGRPRKHTVTSSCSRRSKLKEPDAPSKSKSSSSSSSSTSSSSSSDEEEDDSDLDSKRGPRGRETHPVPQKKAQILVAKPELKDPIRKKRGRKPLPPEQKAARRPVSLAKVLKTTRKDLGTSAAKLPPPLSAPVAGLAALKAHTKEACGGPSTMATPENLASLMKGMAGSPSRGGIWQSSIVHYMNRMSQSQVQAASRLALKAQATNKCGLGLDLKVRTQKGGELGGSPAGGKVPKAPGGGAAEQQRGNHSGSPGAQLAPTQELSLQVLDLQSVKNGVPGVGLLARHAPAKAIPATNPATGKGPGSGPTGANMTNAPTDNNKGEKLTCKATALPAPSVKRDTVKSVAASGGQEGHTAPGEGRKPPALSELSTGEENSSSDSDPDSTSLPSAAQNLSVAIQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSVGFFNLRHY
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (By similarity).  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).  Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (PubMed:16537902).  Plays a role in the lineage differentiation of the germ layers in embryonic development (PubMed:22226355).  Involved in sexual development, acting as activator of NR5A1 expression (By similarity).
What are the official names of this protein?
Chromobox protein homolog 2, M33, Modifier 3 protein.
What are the subcellular locations of this protein?
Nucleus speckle. Chromosome. Note=Localizes to the inactivated X chromosome in females.
Protein: IF1_PSESM
Sequence: MSKEDSFEMEGTVADTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVRVELTPYDLSKGRITYRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D104A_PONPY
Sequence: MRRLVLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDESLLNRTKP
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Beta-defensin 104A, Defensin, beta 104, Defensin, beta 104A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YA11A_YEAST
Sequence: MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECEKASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWSFYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADSDMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELTFLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQYNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNMTVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNNSKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY
What is the function of this protein?
Capsid protein (CA) is the structural component of the virus-like particle (VLP), forming the shell that encapsulates the retrotransposons dimeric RNA genome.  The particles are assembled from trimer-clustered units and there are holes in the capsid shells that allow for the diffusion of macromolecules.  CA has also nucleocapsid-like chaperone activity, promoting primer tRNA(i)-Met annealing to the multipartite primer-binding site (PBS), dimerization of Ty1 RNA and initiation of reverse transcription (By similarity).
What are the official names of this protein?
Transposon Ty1-A Gag polyprotein, Gag-p49, Transposon Ty1 protein A, TY1A, TYA, p58.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_SALA4
Sequence: MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIRSIDDAAKILSFGADKISINSPALADSTLITRLADRFGVQCIVVGIDTWFDDATGKYHVNQYTGDENRTRVTQWETLDWVQEVQQRGAGEIVLNMMNQDGVRNGYDLTQLKKVRDVCRVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLAGQGVEIRIC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEUD_LISIN
Sequence: MEAIKVHIGKTVALMNDNIDTDQIIPKSFLKRIERTGFGEFLFDSWRYLPNRKPNPDFPLNAPDRQEATILITGDNFGCGSSREHAAWALLDYRFRVIIAGSYSDIFYMNCTKNGVLPIVLPREAREKLAKITAEEKVTIDLPKQQVISSVGTYPFEIDATWKNKFINGLDDIAITFEHIDAIKAYEQKVDSI
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: ACEA_CORGL
Sequence: MSNVGKPRTAQEIQQDWDTNPRWNGITRDYTADQVADLQGSVIEEHTLARRGSEILWDAVTQEGDGYINALGALTGNQAVQQVRAGLKAVYLSGWQVAGDANLSGHTYPDQSLYPANSVPSVVRRINNALLRSDEIARTEGDTSVDNWVVPIVADGEAGFGGALNVYELQKAMIAAGAAGTHWEDQLASEKKCGHLGGKVLIPTQQHIRTLNSARLAADVANTPTVVIARTDAEAATLITSDVDERDQPFITGERTAEGYYHVKNGLEPCIARAKSYAPYADMIWMETGTPDLELAKKFAEGVRSEFPDQLLSYNCSPSFNWSAHLEADEIAKFQKELGAMGFKFQFITLAGFHSLNYGMFDLAYGYAREGMTSFVDLQNREFKAAEERGFTAVKHQREVGAGYFDQIATTVDPNSSTTALKGSTEEGQFHN
What is the function of this protein?
Involved in the metabolic adaptation in response to environmental changes.  Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle during growth on fatty acid substrates.
What are the official names of this protein?
Isocitrate lyase, ICL, Isocitrase, Isocitratase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
Protein: ATPI_LOTJA
Sequence: MNVLLCSINTFKRLYDISAVEVGQHFYWQMGDFQVHAQVLITSWVVIAILLGSTILVVRNPQTIPNFGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTLFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGISKKGLAYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, chloroplastic, ATP synthase F0 sector subunit a, F-ATPase subunit IV.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYWM_YEAST
Sequence: MSNKQAVLKLISKRWISTVQRADFKLNSEALHSNATVFSMIQPTGCFHLGNYLGATRVWTDLCELKQPGQELIFGVADLHAITVPKPDGEMFRKFRHEAVASILAVGVDPEKASVIYQSAIPQHSELHWLLSTLASMGLLNRMTQWKSKSNIKQSTNGDYLVNDSDVGKVRLGLFSYPVLQAADILLYKSTHVPVGDDQSQHLELTRHLAEKFNKMYKKNFFPKPVTMLAQTKKVLSLSTPEKKMSKSDPNHDSVIFLNDEPKAIQKKIRKALTDSISDRFYYDPVERPGVSNLINIVSGIQRKSIEDVVEDVSRFNNYRDFKDYVSEVIIEELKGPRTEFEKYINEPTYLHSVVESGMRKAREKAAKNLADIHKIMGF
What is the function of this protein?
Mitochondrial aminoacyl-tRNA synthetase that catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, mitochondrial, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: KTHY_LACLS
Sequence: MNGILISLEGPDGAGKTTVLQEILPEIQKMKREVVPTREPGGVRVAEEIRQIILDPKNTEIDSKTELMLFEAARRLHMQEKMLPALRAGKVVIVDRFIDSSVAYQGYGRDLGVEVVDWLNYFATDGLKPDLTLYFDIDTDVALERIMKNRADEVNRLDLERAEMHRKVREGYLEIVAKEPERFVKIDASQSLEKVVADTLEVLKKRFVSEF
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SYT_HELPG
Sequence: MSAELIAVYKDEQIIDLESAKVLGLSDGIKALKGTEPIYFDDSPLALEVIRHSCAHLLAQSLKALYPDAKFFVGPVVEEGFYYDFKTASKISEEDLPKIEAKMKEFAKLKLAITKEVLTREQALERFKGDELKHAVMSKISGDAFGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGDESNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLPKGARLRKRIEDLLSKALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYGIKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFCSFEQIQSEVSAILDFTHKIMQAFDFSYEMELSTRPAKSIGDDKVWEKATSALKEALKEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNERNHAEQPVMIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKRDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQAQYKMPLKEFLSMVESKMQEVSF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHC_MYCPA
Sequence: MRSWSSPQVPQLPGRGPELRLYDTSDRQVRPVAAGAGPGSAATMYVCGITPYDATHLGHAATYLAFDLIYRQWLDLGHDVHYVQNVTDVDDPLLERAARDGVDWRALAEREVSLFREDMAALRILAPRDYVGATEAIADVVELVEKMLASGAAYVVDGEFPDIYYRADATLQFGYESGYDRETMLRLFAERGGDPQRPGKTDALDALLWRAARPGEPSWPSPFGNGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSQLRGRGVEPAAIRLGLLAGHYRGDRYWSDQVLDEATARLRRWRTATALPAGPDATDVIARVRQYLADDLNTPKALAALDGWTTDALDYGGHDTAAPRLVASAVDALLGVAL
What is the function of this protein?
Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.
What are the official names of this protein?
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, L-Cys:GlcN-Ins ligase, Mycothiol ligase, MSH ligase.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
Protein: HEM3_BRUSI
Sequence: MQTASFKNGTLKIGTRGSKLALAQAYLTRRLLQEAHGLPEDAIEILPMSTAGDRIQDRPLSEVGGKGLFTEEIEQALKDGRIDIAVHSTKDMPTVLPEGLHLSVFLEREDPRDAFIGRSARRFMDLPQGATVGSSSLRRQALIRRLRPDIEVVMYRGNVDTRLRKLDAGEVDGTFLACAGLRRLGLADVITDLLDPSVFPPAPGQGAIGIESRIGDERIDVLLAPLAHRETQIALACERAFLGALDGSCRTPIAGLATVEGDRLSFRGMILTPDGRQAHEVTAEGVVSDAAALGTDAANRVRAMAGPHFFDGWQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: YBAB_SHIB3
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: CORA_WIGBR
Sequence: MLNAFKLHKKNLFRINIDQSSLIKSIWIDIVNLTEEERRRIQNELGQNLSTSLDLEDIEASARFFEDKEGLHIHSFFFFADAEDHVGNSTVAFIIKNNILYTLRERDLPAFRLYRMRARNQTLKDGNAYEVLLDLFETKIEQLADEIENIYSDLETLSIIIMEGRKSNEYDNALSTLAELEDVGWKVRLCLMDTQRAINFLSKKKHIPYEQLDQAKGILHDIDSLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVIFLPPTLVASSYGMNFDFMPELKWPLGYPIAILEMILAGLAPYLYFRRKKWL
What is the function of this protein?
Mediates influx of magnesium ions (By similarity).  Alternates between open and closed states.  Activated by low cytoplasmic Mg(2+) levels.  Inactive when cytoplasmic Mg(2+) levels are high (By similarity).
What are the official names of this protein?
Magnesium transport protein CorA.
What is the protein family that this protein belongs to?
Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FLOA_ALKOO
Sequence: MPEVVFLLIVVAIAFIVLSIILSFIPVGLWITALFSGVKVGIFTLVGMRFRRVQPNRIVGPLIKATKAGLNLDIDDLEAHYLAGGDVNSVVDALIAAQRAEIGLEFERAAAIDLAGRNVLEAVQVSVNPKVIETPKISAVAKDGIEVMVKAKVTVRANIERLVGGAGEETIIARVGEGIVTTVGSALSHKDVLENPDSISKMVLGKGLDAGTAFEILSIDIADIDIARNIGAQLQTDQAEADKRIAQAKAEEKRAMAVAREQEMKAAVIEMKAKVVEAEAEVPRAIAAALREGKLGVMDYYNLQNVAADTTMRESIAKISKDDNDSHGKDITK
What is the function of this protein?
Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts.  FMMs are highly dynamic and increase in number as cells age.  Flotillins are thought to be important factors in membrane fluidity.
What are the official names of this protein?
Flotillin-like protein FloA.
What is the protein family that this protein belongs to?
Belongs to the flotillin-like FloA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein.