PharMolix/UniProtQA huggingface dataset:
Protein: TYW1_PYRHO
Sequence: MMEMITIKPGKITVQANPNMPKEVAELFRKQHYEIVGRHSGVKLCHWLKKSLTEGRFCYKQKFYGIHSHRCLQMTPVLAWCTHNCIFCWRPMENFLGTELPQPWDDPAFIVEESIKAQRKLLIGYKGNPKVDKKKFEEAWNPTHAAISLSGEPMLYPYMGDLVEEFHKRGFTTFIVTNGTIPERLEEMIKEDKLPTQLYVSITAPDIETYNSVNIPMIPDGWERILRFLELMRDLPTRTVVRLTLVKGENMHSPEKYAKLILKARPMFVEAKAYMFVGYSRNRLTINNMPSHQDIREFAEALVKHLPGYHIEDEYEPSRVVLIMRDDVDPQGTGVEGRFIKH
What is the function of this protein?
Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).
What are the official names of this protein?
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, tRNA wyosine derivatives biosynthesis protein Taw1.
What is the protein family that this protein belongs to?
Belongs to the TYW1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCX6_TRICV
Sequence: MVWLVWKRSTISRKNKKFFKTIFKKN
What are the official names of this protein?
Uncharacterized 3.3 kDa protein in psbJ-trnE intergenic region, ORF26A.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NUOB_GEOUR
Sequence: MGVEQPLGDNIVTASLDGLVNWARKSSIWPMTFGLACCAIEMMATGAAKHDLDRFGIIFRASPRQSDCIIIAGTVTKKMLPVIKTVYEQMPEPKWVIAMGACACSGGVFDTYSVVQGVDEALPVDVYIPGCPPRPEALLYGLMKLQDKIGKERNSFGSAIGLGDRLEPAA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: XYLG_SHIBS
Sequence: MPYLLEMKNITKTFGSVKAIDNVSLRLNAGEIVSLCGENGSGKSTLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENIFLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQVRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDGQHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKRVNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQAIAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQLKVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHVEKQSV
What is the function of this protein?
Part of the ABC transporter complex XylFGH involved in xylose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Xylose import ATP-binding protein XylG.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HTPX_PSECP
Sequence: MHKHHNGLKTAALFGVLWAVLLALGALIGAGTRSSAPIWIMALVGVGTTFYGYWNSDKIAIRSMQAFEVSEAQAPQLYQIVRELSARANQPMPRIYVSPTMNPNAFATGRNPQNAAVCCTEGILQLLDARELRGVLGHELMHVYNRDILTSSVAAAVAGVITSVGQMLLFFGGGDRRNANPLAMIAMALLAPFAASLIQMAISRTREYDADEDGSQLTGDPLALASALAKIERGVTMVPLPPDQRLVNASHLMIANPFRGGAMNKLFATHPPMRDRIARLERMAGRPLQ
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAPR_MUCCL
Sequence: MITDEHPFEFAPQQDEYTQLLTELHNEYCAEQPLDVLQFCSNFFIRKLEEQRLEHRNNHHSRNNLFDTNDTSNDLHPLCEQPQEDFSQQQGIQWETTHMGHPNDHGALHDDDDDPLEDEDDEEFDKFSTEPLPSLPPTNYNRGRRTSVKCREHGTQRQPRLCQGHHPQISGTSERIKVSISNNFLFRNLDEEQYLDVVNAMSEKRVVKGTTVIEQGSVGDFFYVVESGTLDCFIGQNKVTNYEAGGSFGELALMYNAPRAATIITTSDSVLWALDRNTSAPSLMENTSRKRRMYEYFLSEVVLLKSLESYEQHKIADALESVYFEDGQEVVKQGDVGDQFYIIESGEAIVLKEENGVQQQVNQLERGSYFGELALLNDAPRAATVVAHGRLKCATLGKKAFTRLLGPVLDILKRNSENYHAVINQQS
What are the official names of this protein?
cAMP-dependent protein kinase regulatory subunit, PKA regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
Protein: FAR17_SARBU
Sequence: PDNFMRF
What are the official names of this protein?
SabFMRFamide-17.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KHDC1_HUMAN
Sequence: MLSAFQRLFRVLFVIETVSEYGVLIFIYGWPFLQTLAMLLIGTVSFHLWIRRNRERNSRSGKTRCRSKRSEQSMDMGTSALSKKPWWTLPQNFHAPMVFHMEEDQEELIFGHGDTYLRCIEVHSHTLIQLESWFTATGQTRVTVVGPHRARQWLLHMFCCVGSQDSYHHARGLEMLERVRSQPLTNDDLVTSISVPPYTGDLSLAPRISGTVCLSVPQPSPYQVIGCSGFHLSSLYP
What are the official names of this protein?
KH homology domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the KHDC1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TSAD_MYCLE
Sequence: MTISAVPGTIILAIETSCDETGVGIACLDDYGTVTLLADEVASSVDEQARFGGVVPEIASRAHLEALGPTIRCALAAAGLTGSAKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYEHGPLPECVALLVSGGHTHLLQVRSLGAPIVELGSTVDDAAGEAYDKVARLLGLGYPGGKVLDDLARTGDRDAIVFPRGMTGPADDLNAFSFSGLKTAVARYVESHPDALPADVAAGFQEAVADVLTMKAVRAATGLGVSTLLIVGGVAANSRLRELAAQRCAAAGLMLRIPGPRFCTDNGAMIAAFAAHLLAAAAPPSPLDVPSDPGLPVVKRQIN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_GEOMG
Sequence: MKSLTLKAPAKVNYRLDVLRRRPDGYHDLRMIMQRIDLCDEITITLSDTSGVRVTCGREGVPDGPENIAWRAANALLALSGLETGIDIAITKNIPVAAGLGGGSSDAATVLLGVNELLGLGLSIERLMEVGVTLGADVPFFVFGKTALAEGIGEVLTAIDAVPPLWLVIVNPNIPVSTAWVYQSLRLTGEWNGDTIPRFFKDVADVCAVLANDLELVTIERYPVIGEIKERLVAAGAAGALMSGSGPTVFGLFASEEEARGAAQSITNSSDWFVVAVRALV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: BAGLU_SCUBA
Sequence: MGFQVWQKGLCVLCFSLIFICGVIGEETTIVKIEENPVAQTDENYVCATLDLWPPTKCNYGNCPWGKSSFLNLDLNNNIIRNAVKEFAPLKLRFGGTLQDRLVYQTSRDEPCDSTFYNNTNLILDFSHACLSLDRWDEINQFILETGSEAVFGLNALRGKTVEIKGIIKDGQYLGETTTAVGEWDYSNSKFLIEYSLKKGYKHIRGWTLGNELGGHTLFIGVSPEDYANDAKKLHELVKEIYQDQGTMPLIIAPGAIFDLEWYTEFIDRTPELHVATHHMYNLGSGGDDALKDVLLTASFFDEATKSMYEGLQKIVNRPGTKAVAWIGEAGGAFNSGQDGISNTFINGFWYLNMLGYSALLDTKTFCRQTLTGGNYGLLQTGTYIPNPDYYSALLWHRLMGSKVLKTEIVGTKNVYIYAHCAKKSNGITMLVLNHDGESSVKISLDPSKYGSKREEYHLTPVNNNLQSRLVKLNGELLHLDPSGVIPALNPVEKDNSKQLEVAPYSFMFVHLPGPTMFSACEKPAGK
What is the function of this protein?
Beta-glucuronidase involved in the initiation of H(2)O(2) metabolism via the production of baicalein.  Unable to use glycyrrhizin, gypsogenin-3-O-D-glucuronide, luteolin-7-O-D-glucoside and apigenin-7-O-D-glucoside as substrates.
What are the official names of this protein?
Baicalin-beta-D-glucuronidase, Baicalinase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 79 family.
Protein: 3L21_HYDST
Sequence: LSCYLGYKHSQTCPPGENVCFVKTWCDGFCNTRGERIIMGCAATCPTAKSGVHIACCSTDNCNIYAKWGS
What is the function of this protein?
Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission.
What are the official names of this protein?
Alpha-elapitoxin-Ast2a, Alpha-EPTX-Ast2a, Long neurotoxin 1, Toxin B.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Long-chain subfamily. Type II alpha-neurotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DYLT1_RAT
Sequence: MEDFQASEETAFVVDEVSNIVKEAIESAIGGNAYQHSKVNQWTTNVVEQTLSQLTKLGKPFKYIVTCVIMQKNGAGLHTASSCFWDSSTDGSCTVRWENKTMYCIVSAFGLSI
What is the function of this protein?
Plays a role in neuronal morphogenesis; the function is independent of cytoplasmic dynein and seems to be coupled to regulation of the actin cytoskeleton by enhancing Rac1 activity.  Required for neurite outgrowth.  The function in neurogenesis may be regulated by association with a G-protein beta-gamma dimer.  May function as a receptor-independent activator of heterotrimeric G-protein signaling; the activation appears to be independent of a nucleotide exchange.  Plays a role in regulating neurogenesis; inhibits the genesis of neurons from precursor cells during cortical development presumably by antagonizing ARHGEF2.  Unrelated to the role in retrograde microtubule-associated movement may play a role in the dimerization of cytoplasmic proteins/domains such as for ACVR2B.  Binds to the cytoplasmic domain of ACVR2B and, in vitro, inhibits ACVR2B signaling (By similarity).  Involved in the regulation of mitotic spindle orientation.
What are the official names of this protein?
Dynein light chain Tctex-type 1, Activator of G-protein signaling 2, AGS2, T-complex testis-specific protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the dynein light chain Tctex-type family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to mitotic spindles.
Protein: UT1_CAPHI
Sequence: MDDNPTAVKLDQGGNQAPQGQGRRRLPKALGYITGDMKEFANWLKDKPQALQFVDWVLRGISQVVFVSNPISGILILVGLLVQNPWCALNGCVGTVVSTLTALLLNQDRSAITAGLQGYNATLVGILMAIYSDKGNYFWWLLFPVSAMSMTCPIFSSALNSVLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPSTLVTPVTSVPNVTWPDLSALQLLKSLPVGVGQIYGCDNPWAGGIFLGAILLSSPLMCLHAAIGSLLGIIAGLSLSAPFENIYAGLWGFNSSLACIAIGGMFMALTWQTHLLALACALFTAYLGASMSHVMAVVGLPSCTWPFCLATLLFLLLTTKNPNIYKMPISKVTYPEENRIFYLQSTKRTVQGPL
What is the function of this protein?
Mediates the transport of urea driven by a concentration gradient across the cell membranes of erythrocytes and the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity).  Facilitates water transport in erythrocytes (By similarity).
What are the official names of this protein?
Urea transporter 1, Solute carrier family 14 member 1, Urea transporter B, UT-B, Urea transporter, erythrocyte.
What is the protein family that this protein belongs to?
Belongs to the urea transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Restricted to the basolateral membrane in various portions of the urothelium.
Protein: ARLY_VIBC3
Sequence: MALWGGRFTQAADSRFKSFNDSLRFDYRLAEQDIVGSIAWSKALVSVNVLSVQEQQQLEQALNHLLQSVQQDPEQILASDAEDIHSWVEQKLIEQVGDLGKKLHTGRSRNDQVATDLKLWCRDQGVHLLLALKTLQQQLVAVAAEHQSTVLPGYTHLQRAQPVTFTHWCLAYLEMFERDESRLTDALARLNTSPLGSGALAGTAYAIDREVLAADLGFTRATRNSLDAVSDRDHVMELMSVASISMLHLSRLAEDMIFYTTGEAGFIELADTVTSGSSLMPQKKNPDALELIRGKTGRVYGALAGMMMTVKALPLAYNKDMQEDKEGLFDALDTWFDCLQMAGLCFDGIKVNAARTLEAAKQGYSNATELADYLVAKGIPFREAHHIVGVAVVAAIGKGVALEELCLAELQQFSPLIEQDVYPILTIESCLEKRCALGGVSPKQVAHALQQAQARVKS
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_ACIBC
Sequence: MNLKTVSGSAVELSEVAFGREFNEALVHQVVTAYLAGGRQGTRAHKSRADVSGGGKKPFRQKGTGRARAGSIRSPIWVGGGKTFAARPQDWSQKVNRKMYRGAMQCILAELVRQDRLVLVEEFAVAAPKTKELLAKLNDLNAARALIVTDAVDENLYLAARNLPHVDVVDATAIDPVSLIAFDKVVMSVAAAKKIEVELG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: NDPA_CROS8
Sequence: MSLDINQIALHQLIKRDEQNLELILRDSLLEPGNTVTEMMAELHRVYSAKSKAYGLFNEESELAEALRQCRRGDEDFLAFSRAATGRLRDELAKYPFAEGGIVLFCHYRYLAVEYLLVAVLNNLSSMRVNEQLDISTTHYLDINHADIVARIDLTEWETNPESTRYLTFLKGRVGRKVADFFMDFLGASVGLDTKAQNRGLLQALDDFTAEAQLDKAERQNVRAQVYSYCNEQLQAGEEIALSELSKELPSFGEKSFQEFTAEQGYELEETFPADRSTLRQLTKYAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGK
What are the official names of this protein?
Nucleoid-associated protein ESA_01050.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RL20_FRAAA
Sequence: MARVKRAVNAQKKRRTVLEQASGYRGQRSRLYRKAKEQMLHSMTYSYRDRRARKGDFRQLWITRINAAARANGLTYNRFVQGLKLSGVEVDRKILADLAVNDAAAFTALVEVARAALAAAPEPTAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: AGO4A_ORYSJ
Sequence: MESNSGEIEELPPPPPLPPNAEPIKTDDTKKLSKPKRALMARSGCGKKGQPIQLLTNHFKVSLKAADEFFHHYYVNLKYEDDRPVDGKGIGRKVLDKLQQTYASELANKDFAYDGEKSLFTIGALPQVNNEFTVVLEDFNTGKSSANGGSPGNDSPGNDRKRVRRPYQTKTFKVELNFAAKIPMSAIAQALRGQESENTQEAIRVIDIILRQHSAKQGCLLVRQSFFHNNPSNFVDLGGGVMGCRGFHSSFRATQSGLSLNIDVSTTMIVKPGPVVDFLLANQKVDHPNKIDWAKAKRALKNLRIKTSPANTEYKIVGLSERNCYEQMFTLKQRNGDGEPEGVEVSVYEYFVKNRGIELRYSGDFPCINVGKPKRPTYFPIELCSLVPLQRYTKALSTLQRSSLVEKSRQKPEERMSVLSDVLKRSNYDSEPMLNSCGISIARGFTQVAGRVLQAPKLKAGNGEDLFARNGRWNFNNKRLIKASSIEKWAVVNFSARCNIRDLVRDIIKCGGMKGIKVEDPFDVIEEDPSMRRAPAARRVDGMIDKMQKKLPGQPKFLLCVLAERKNSDIYGPWKRKCLAEFGIITQCVAPTRVNDQYITNVLLKINAKLGGLNSLLQIETSPSIPLVSKVPTIILGMDVSHGSPGQSDIPSIAAVVSSREWPLVSKYRASVRSQSPKLEMIDGLFKPQGAQEDDGLIRELLVDFYTSTGKRKPDQVIIFRDGVSESQFTQVLNIELDQIIEACKFLDENWSPKFTLIVAQKNHHTKFFVPGSQNNVPPGTVVDNAVCHPRNNDFYMCAHAGMIGTTRPTHYHILHDEIGFSADDLQELVHSLSYVYQRSTTAISVVAPICYAHLAAAQVSQFIKFDEMSETSSSHGGHTSAGSAPVPELPRLHNKVRSSMFFC
What is the function of this protein?
Probably involved in the RNA silencing pathway.  May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity).
What are the official names of this protein?
Protein argonaute 4A, OsAGO4a.
What is the protein family that this protein belongs to?
Belongs to the argonaute family. Ago subfamily.
Protein: RL11_MYCLB
Sequence: MATKKKVAGLIKLQIQAGQANPAPPVGPALGQHGVNIMEFCKAYNAATENQRGQVIPVEITVYEDRSFTFALKTPPAAKLLLDAAGVGKGVAEPHKTKVVKVSWDQVREIAETKKADLNANDIDAAAKIIAGTARSMGITVE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: PSAJ_TRICV
Sequence: MNDLQKYLSTAPVLLTLWMTFTAGFIIEINRFFPDMLGLYF
What is the function of this protein?
May help in the organization of the PsaE and PsaF subunits.
What are the official names of this protein?
Photosystem I reaction center subunit IX, PSI-J.
What is the protein family that this protein belongs to?
Belongs to the PsaJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RR3_EUCGG
Sequence: MGQKINPLGFRLGTTQGHHSIWFAQAKNYSDGLQEDQKIRNCIKNYLQKNMRISSGVEGIARIEIRKRIDLIQVIIYMGFPKLLLEGKTRRIEELQMNVQKELNCVNRKLNIAITRITNPYGHPNILAEFIAGQLKNRVSFRKAIKKAIELTEQADTKGIQVQIAGRLDGKEIARVEWMREGRVPLQTIRAKIDYCSYGVRTVYGVLGIKIWIFWE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MBD7_ARATH
Sequence: MQTRSSSSPSANHRRETQLQIADPTSFCGKIMPGWTVVNRPRSSNNGVVDTYFIEPGTGRQFSSLEAIHRHLAGEVNDRRLTRAGSFFQDKTRVYEGSRTKQDHCGVEYASKGFRLPRGWSVEEVPRKNSHYIDKYYVERKTGKRFRSLVSVERYLRESRNSIEQQLRVLQNRRGHSKDFRLPDGWIVEEKPRRSSSHIDRSYIEPGTGNKFRSMAAVERYLISVGNITLDSVSMVHSERLPLLMNRNGIRFQSEVIDPNPPKKVKWVLTGSGGNMFTANVRGSNVSSLVKHTWSEAFVSLIEDRS
What is the function of this protein?
Transcriptional regulator that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides.  May directly affect chromatin structure by inducing intra- and inter- chromatin compaction via bridging over multiple methylated CpG sites.  Acts as an anti-silencing factor that prevents DNA hypermethylation and gene repression (PubMed:25684209).  Requires high mCG density for binding (PubMed:25684209, PubMed:25593350).  Recognizes preferentially mCGs located in transposable elements (PubMed:25684209, PubMed:25593350).  Required for active DNA demethylation (PubMed:25593350).  Prefers to target genomic loci around chromocenters (PubMed:25593350).
What are the official names of this protein?
Methyl-CpG-binding domain-containing protein 7, AtMBD7, MBD07, Methyl-CpG-binding protein MBD7.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associated with heterochromatin, at all chromocenters. Excluded from nucleolus.
Protein: APT_PSYIN
Sequence: MTAPTLEEIKNCIKSIPDYPIPGIMFRDITSLIENGAAFSATINLLVERYKDQNISKVVGTEARGFIFGAPLAAAIGAGFVPVRKPGKLPRTTVHENYELEYGTDSLHIHSDAIKKNERVLLVDDLLATGGTAEASIKLIHRSGGIVIESAFVIELPALKGAQKLHALNVPYFSLIKFEGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXS_MYCBP
Sequence: MDPAGNPATGTARVKRGMAEMLKGGVIMDVVTPEQARIAEGAGAVAVMALERVPADIRAQGGVSRMSDPDMIEGIIAAVTIPVMAKVRIGHFVEAQILQTLGVDYIDESEVLTPADYAHHIDKWNFTVPFVCGATNLGEALRRISEGAAMIRSKGEAGTGDVSNATTHMRAIGGEIRRLTSMSEDELFVAAKELQAPYELVAEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGAPEHRAAAIVKATTFFDDPDVLAKVSRGLGEAMVGINVDEIAVGHRLAQRGW
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by the PdxT subunit.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxS, PLP synthase subunit PdxS, Pdx1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: ERPA_XYLF2
Sequence: MTMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQYGFEFDENRADDDLALETDGVVLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: WZYE_ESCF3
Sequence: MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRTTDVPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NADD_PSESM
Sequence: MTTLPRRIGMLGGTFDPVHIGHLRGALEVAELLELDELRLTPSARPPHRDMPSVTAQDRLAMVRSAVAGVSPLTVDDRELKRDKPSYTLDTLESMRAELAPRDQLFLLLGWDAFCGLPTWHRWEELLEHCHIVVLQRPDADSESPDAMRNLLAARAVSDPKALKGPGGQITFVWQTPLSVSATQIRQLLASGKSVRFLVPDAVLAYIDVHGLYRAPNTDGSP
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: RS9_SHEPA
Sequence: MAATQYYGTGRRKTSTARVFAKVGTGNIIVNKLPLDEYFGRETSRMVVRQPLELVEMTEKLDIMVTVKGGGNTGQAGAIRHGITRALMELDESLRPSLRAAGFVTRDARKVERKKVGLRKARRKPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: GLK_RHIME
Sequence: MPNASEHSFPFPILIGDIGGTNARFALLTDAYGEPKQLAPIRTGDFATIEEAMQKGILDKTSVQPRSAILAVAGPIKGDEIPLTNAGWVIRPKDMLAGLGLEDVLVINDFEAQALAIAAPADQDVVQIGGGAVRPFHSRVVLGPGTGLGVAGLVYAQHTWIPVPGEGGHVDIGPRTERDFRIWPFLEPIEGRMAGEQILCGRGIMNLYRAVCAANGEEAVLADQAAVTTSALSGADAAAVETVSLFATYLGRVAGDMALIFMARGGVFLAGGISQKILPALTKPEFRAAFEDKAPHSALMRTIPTFAVIHPMAALSGLAAFARTPRDFGVAMEGRRWRR
What are the official names of this protein?
Glucokinase, Glucose kinase.
What is the protein family that this protein belongs to?
Belongs to the bacterial glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTS3_MYCTU
Sequence: MKLNRFGAAVGVLAAGALVLSACGNDDNVTGGGATTGQASAKVDCGGKKTLKASGSTAQANAMTRFVNVFEQACPGQTLNYTANGSGAGISEFNGNQTDFGGSDVPLSKDEAAAAQRRCGSPAWNLPVVFGPIAVTYNLNSVSSLNLDGPTLAKIFNGSITQWNNPAIQALNRDFTLPGERIHVVFRSDESGTTDNFQRYLQAASNGAWGKGAGKSFQGGVGEGARGNDGTSAAAKNTPGSITYNEWSFAQAQHLTMANIVTSAGGDPVAITIDSVGQTIAGATISGVGNDLVLDTDSFYRPKRPGSYPIVLATYEIVCSKYPDSQVGTAVKAFLQSTIGAGQSGLGDNGYIPIPDEFKSRLSTAVNAIA
What is the function of this protein?
Functions in inorganic phosphate uptake, is probably the main carrier for phosphate uptake, it is the most highly expressed of the 3 PstS proteins under phosphate starvation (PubMed:20933472).  Binds phosphate; probably able to bind both H(2)PO(4)(-) and HPO(4)(2-) (PubMed:24615888).  Part of the ABC transporter complex PstSACB involved in phosphate import (Probable).  Probably plays a role in host phagosome maturation arrest (PubMed:20844580).
What are the official names of this protein?
Phosphate-binding protein PstS 3, PBP 3, PstS-3, Antigen Ag88.
What is the protein family that this protein belongs to?
Belongs to the PstS family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.