PharMolix/UniProtQA huggingface dataset:
Protein: MTC3_PBCVC
Sequence: MNVEQYTQVTTDFEKTLTKEKKSKQGIFFTPKTVREKLFGFTEHFQNTPGFSILEPSCGTGEIISECVERFPLASIKGVELDNDMSTICSKKYAEYNVDIVNEDFLLWKGGKFDFIVGNPPYVVRPSGYKNDNRIAKGRSNLYVEFLYKCITEHLKEDGILAFIIPSTIGNSSFYEPIRKLIITLDILSFEILDKHDFCDTNTRLCSIVIKNSPGTGKYTYRDYICDKDIPHHGNSYIGSLDLKFKTGFAWANVNKFFTDKSEIPFFTSSNIKLNEIHIGDKMKYLTQDTTKFFTGKALLIKTASAGKRGGRFEFGFSLYENDKWAVDNDIIVIQGPDTVLSIVQDVLMKDVTNEFINILVNNGHISMKLLKSIPLF
What is the function of this protein?
A gamma subtype methylase that recognizes the double-stranded sequence 5'-TCGA-3' and methylates A-4 on both strands.
What are the official names of this protein?
Modification methylase CviBIII, M.CviBIII, Adenine-specific methyltransferase CviBIII, Orphan methyltransferase M.CviBIII.
What is the protein family that this protein belongs to?
Belongs to the N(4)/N(6)-methyltransferase family.
Protein: RLA1_TRYCR
Sequence: MSSKQQLACTYAALILADSGKTDMDSLLKVTKAAGVDVSKGMASAFASILKNVDINDVLSKVSFGGVAPAAGGATAAPAAAAAAAAPAAAAAKKEEEEEDDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P1.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: MTOX_SALEP
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLKVLMTDAHMPPHQQGSHHGDTRLIRHAYGEGEKYVPLMLRAQTLWDELSTHNEEPIFVRSGVVNLGPADSAFLANVARSAQQWQLNVERLDATALMTRWPEIRVPDNYIGLFEADSGFLRSELAITTWLRLAREAGCAQLFNSQVSHIHHDDNGVTIETSEGSYHASKALISAGTWVKALVPELPVQPVRKVFAWFKADGRYSTKNRFPAFTGEMPNGDQYYGFPAENDELKIGKHNGGQLIQAPEERKPFAAVASDGAEAFPFLRNVLPGIGGCLHGAACTYDNSPDENFIIDTLPGHENTLVITGLSGHGFKFAPVLGEIAADFALGKTSSFDLTPFRLSRFSQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: TFXC_RHILT
Sequence: MIELRPLLQLNLEDGIPVLKDLLTADSFSFTDVELLRYIPAIAKNTPAQTRDLAASVADALDVDQTTALAAIEALVELGLLVPSASISSQKAGIQLWVDKGWVDALILHFASRNLNYNDDPIEFGGLEDIKSYPEPMESKRRKRGTATRLVKPSRELAAAVILDGLMNRRSFKPFTRKQLSITEVSEILWFGNLYARERAVIAENRDFESPRDIAFDSAFSALSTFVVTYGQIDWQDGSLPPGVYRYNVVNHELEAIRAGDFKLDMAKLAIGQSRASSGLFTFVICGDLKSYTSRYRHERSYRNLLINTSQLAQFYLTLATINDFNTFLTPAIHDEKMHLFLEAEDDLPLYLVTAG
What are the official names of this protein?
Trifolitoxin operon protein TfxC.
Protein: CYT1_HORVU
Sequence: MAEAAHGGGLRGRGVLLGGVQDAPAGRENDLETIELARFAVAEHNAKANALLEFEKLVKVRQQVVAGCMHYFTIEVKEGGAKKLYEAKVWEKAWENFKQLQEFKPAA
What is the function of this protein?
Inhibits papain, ficin, cathepsin B and, to a lesser extent, chymopapain, but is inactive against bromelain.  Inhibits the growth of pathogenic fungi.  Regulated by the DOF transcription factors SAD (activator) and BPBF (repressor).
What are the official names of this protein?
Cysteine proteinase inhibitor, Cystatin, Hv-CPI.
What is the protein family that this protein belongs to?
Belongs to the cystatin family. Phytocystatin subfamily.
Protein: RBM42_DANRE
Sequence: MALKSGEERLKEMEAEMALFEQEVLGGPVAPTVVEAVPVALAMPTLPMVRPIIGTNTYREVQQSLEARAATLVGPPPTFVCPAIPAVPPPQVLRPAFVPHVLQRPAGGHRMPMMRGPPPHGMIAPPLPRPPPPPPSMMAPPVVGPPQPPMAPVGPPMGPMPPVGGMNPMALGPPRSMTQAPAKITPSVIQAAPTVYTAPPVSKRIDLKSQKQARMEQLSALVAEQQAAVLAAGLLDSKKETASDDSVIGPSMPEPEPVHVEPVDTSTEDKKKGKQEKVKKCIRVAAGVSWEDTSLLEWETDDFRIFCGDLGNEVNDDILARAFSRYPSFLKAKVVRDKRTGKTKGYGFVSFKDPNDYVRAMREMNGRYVGSRPIKLRKSAWKDRNLEVVRKNQKEKKKLGLR
What is the function of this protein?
May bind RNA.
What are the official names of this protein?
RNA-binding protein 42, RNA-binding motif protein 42.
What is the protein family that this protein belongs to?
Belongs to the RRM RBM42 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: ISCR_YERPG
Sequence: MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINVNLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: TRM56_METBF
Sequence: MKRIVLLRLGHRPERDKRITTHVGLTARLLGAEGMLLASNDPGIIATLEDVVSRWGGNFYIKNNVNYKQEIKEWKAAGGKVCHLSMYGINLPDVTDELKSCDKLMIVVGAEKVPPEIYQLADWNVAVGSQPHSEVAAVAITLDRIADGEPLKREFQNAELTIVPAERGKQVIENLRD
What is the function of this protein?
Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.
What are the official names of this protein?
tRNA (cytidine(56)-2'-O)-methyltransferase, tRNA ribose 2'-O-methyltransferase aTrm56.
What is the protein family that this protein belongs to?
Belongs to the aTrm56 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_ERWT9
Sequence: MSLTLWQQCLARLQDELPATEFSMWIRPLQAELNDNTLALYAPNRFVLDWVRDKYLNNINALLNEFCGANVPLLRFEVGSKPVAQAISQPVMVSAHASAPGVVSRPAPTRPSWDNVPALAELSYRSNVNTKHNFDNFVEGKSNQLARAAARQVADNPGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRSRSVARPRQMAMAMAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENV1_DROME
Sequence: TFPLQLGSKLCQGKSEHCSITLSLISRFTLMMFIPLVVANARITDFSHANYIPVLDGDVLVFEQRDLLKHSSNLSEYASMIDETQKLSESFPHSHMRKLLEVDTDHLRTLLSVLKVHHRIARSLDFLGTALKVVAGTPDATDLFKIKITEAQLVESNSRQIAINSETQKQINKLTDTINKVINARKGDLVDTPHLYEALLARNRMLSTEIQNLILTITLVKSNIINPTILDHADLKPLVEQDTPIVSLIEASKIRVLQSENSIHILIAYPRVKFSCKKVAVYPVSHQHTILRLDEDTLAECEHDTFAVTGCTDTTHFTFCERSRRETCVRSLHAGNAAQCHTQPSHLREINPVDDGVVIINEAAAHVSTDGSPETLIEGTYLVTFERTATINGSEFVNLRKTLSKQPGIVRSPLLNIVGHDPVLSIPLLHRMSNENLHSIQNLMDDVESEGSPRLWFVAGVVLNFGLIGSLALYLALRRRRASREIQRTIDTFNMTEDGHKLEGGVVNN
What are the official names of this protein?
Retrovirus-related Env polyprotein from transposon gypsy.
Protein: METK_LEGPH
Sequence: MNEVYVFTSESVSEGHPDKIADQISDAILDAILAQDPKARVACEVLVKTGMVLVGGEITTKAWVDVEEITRHVIKDIGYNSSQMGFDWESCAVLSAIGKQSPDIAQGVDNQQTKILGAGDQGLMFGYASRETDVFMPAPIAYAHRLMEKLAKARKSGQLPWLRPDAKCQLTLKYEQGMPVEVDTVVFSTQHSPDIEHKDLVEAIREEIIKSVLPAEWLNDKTRYFINPTGRFVIGGPLGDCGLTGRKIIVDTYGGMARHGGGCFSGKDPSKVDRSAAYAARHVAKNIVAAGLADKCELQISYAIGVAEPTSIFVDTFGTGRLKNSEIIDLIHTHFDLTPQGIIDQHDLLRPIYRQTATYGHYGRESFPWERLDKVAELSKAL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_YERPY
Sequence: MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHSEQLPALFNGVPIGTRISV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SEY1_CANTT
Sequence: MSSELSEGELSHTSSSSSFVPVDQRQLQDAIQIINEEKRFNQSVLEYINKTAPADVGNNYHIISVFGSQSTGKSTLLNKLFNTNFDVMDESNRQQTTKGIWLAFSPVVSTTSGHTSSKSNILVMDVEGTDGRERGEDQDFERKAALFALSTSEILIINIWETQVGLYQGANMGLLKTVFEVNLSLFGKSKLEKHDDHKVLLLIVIRDYVGVTPVESLAKTFTQDLINMWASLAKPAELEHLQFADFFDVDFHALNHKVLQPKEFSEGINKLGDRLVVGDELFKPEYHHQVPIDGWVMYAGNCWEQIETNKDLDLPTQQILVAQFKCDEIVENVFQEFLKKFEQLFGEPQAEPDYEQIGALFSDLRNDTLEDYDISASKYNKSVYEQKRVKLISLVNEKFKEVFDFYAKELSSTMLKKFHSDVVALKGKNFAASVKELSTGLIASIVTTLGLISLQGDLSSNEVTTALSKDIADIVSKQQVIELNSIVNRAVKKLTNSLSKSIQFELGDPNENTWDTVLQQFNSLSQEVLTKYDGDFGLGTTDEQNKQALDRFQFKSWTSFYESMHKLISKEKLLVLLQDRFDDVFRYDENGLPKLYLNEADLEKTFTESKQHALKVLPILTIAKLSDGSEIVPEIDIFDHKLREKYLGVADEDSDDEDDDEHCFAEIVTEQEKSEVLAKFKKEVDAKYIETKRSIVQHITQIPYYIYLVIVFLGWNEFMAIIRNPLLFSLALLLGASVYILYKLNLLKPAIVVAQRTFDETVAMGKEKLREILIDDHETQGRNLGKIAGKNPSAPAEEYSDNIELDDM
What is the function of this protein?
Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network.  Has GTPase activity, which is required for its function in ER organization.
What are the official names of this protein?
Protein SEY1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Enriched in the cortical ER. Concentrated in punctae along the ER tubules.
Protein: CASK_TRAJA
Sequence: VAQVQYQEQLTGCENDERFFNDKTIKYIPIPYLLNRYPSYGLNYYQQRPPALINNQFLPFSFYAKPMAVRSPAQILQWQVPLNAVSAKPCQAPPTTMARRPRPHLSFMAIPPKKDQDKTDTPTINTIVTVEPTTTPTTESIVNTVATLEASSESIASAPETTTVQVTSAEV
What is the function of this protein?
Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
What are the official names of this protein?
Kappa-casein.
What is the protein family that this protein belongs to?
Belongs to the kappa-casein family.
What are the subcellular locations of this protein?
Secreted.
Protein: GCH4_STAA8
Sequence: MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFLFEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIELEFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDKVTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQDIVDDYKNKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNEESIHQHDAFAKLKYRK
What is the function of this protein?
Converts GTP to 7,8-dihydroneopterin triphosphate.
What are the official names of this protein?
GTP cyclohydrolase FolE2.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: SGS3_SOLLC
Sequence: MSFSKWGGKPSNSSEKQKASSTPTVEEINRGVGDIGLNSEQNEGWEVYARKPKNKGGSSAGKQWAPQNPSPKAWGNQNTKAWGHPDVGKKSGTRNNAGSGRGSGNNWSTPSDPQKLARPHLYDGGFPSSAPVPPALKNGWDWSSRVASAHPKDNSQVAAAADDDKASEHDAEDNELDFLDESDDDLHSDDFDSDVGEMSYETRKKNPWFNQLFHSLDSLTVTEINEPERQWHCPACKGGPGAIEWFTGLQSLMTHAKTKGLRVKIHRELAELLEEDLRQRGTSVVPPGEVYGRWGGMEFKDKEIVWPPMVIIMNTRLDKDENDKWIGMGNQELLEYFSSYAAVKARHSYGPQGHRGMSLLIFEASAVGYIEADRLSEHFSENGRNRDAWERRSARFYPGGKRLLYGYMADKKDIDNFNQHSAGKSKLKFEMRSYKEAVWNPAKQMREDNQQLIWFKNKAAKHQMQAKALEESLSLVSEKHRQTLEENKIVRLKTKMHHEQIKEEMEFQEQFFKDQIKIIHDARTAREDNFEKTQQEQREMVKQSNANTASVEDHRVRAEKVAKFIKLQDKEMEEFVEERENLMRTHDDRIAALRRKYWEEEVELERKFDLELSKLMEKYSPKQSDEVNSSGTM
What is the function of this protein?
Required for post-transcriptional gene silencing and natural virus resistance.
What are the official names of this protein?
Protein SUPPRESSOR OF GENE SILENCING 3, SlSGS3.
What is the protein family that this protein belongs to?
Belongs to the SGS3 family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Note=Accumulates in inclusion bodies in the cell periphery. May interact with the ER network from the perinuclear region out to the cell periphery (By similarity).
Protein: RL10_SULTO
Sequence: MAVITQERKIAKWKIEEVKELEQKLREYHTIIIANIEGFPADKLHDIRKKMRGMAEIKVTKNTLFGIAAKNAGLDVSKLEPYLTGPNAFIFTNKNPFEIQLFLSKFKLKRYAMPGDKADEEVVIPAGDTGMPAGPALSIFGKLKIKTKVQDGKIHVTQDTVIAKPGDPIPPDAIPILQKLGIMPVHIKLNIKVAYDNGLIIPGNQLSINLDDYKTDIMKAYQSAFGLAVEIAYPIPDVLKVSAEKAARNALSLAAEIGFITPETVQAVFSRAISKAYALASAISGKVDLGIQVPQTQQAPAQQAEKKEEKKEEEEKKGPSEEEIGGGLSSLFGG
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10, Acidic ribosomal protein P0 homolog.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RNC_EHRCR
Sequence: MIESISKIIKYNFKNPQLLNEALTHPSLVSKDTLKFNYERLEFLGDAVLNIVISEMLFNIFPKDTEGNLAKKKTALVCGNKLVEVAQSINLGQFIMMSDGERACGGINNFRNLENALEALIGAIYLDGGFTAAQDFIYLFWEHSATHMNVPPQDAKTILQELVQGKRLPAPAYHTIDKSGPDHNPTFTVEVRIPSYQAIQATGHNKKLAEQKAASLMLNQIHNKTK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RXL7_STAA2
Sequence: MSKEKVARFNKQHFVVGLKETLKALKKDQVTSLIIAEDVEVYLMTRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK
What are the official names of this protein?
Putative ribosomal protein L7Ae-like.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
Protein: OBG_BLOPB
Sequence: MKFVDMTNITVIAGNGGNGCVSFQKSGRRASFLKKPNGSNGGNGGDVWLLADPNINTLNYFHSNCVFRAGHGQSGRSRGCTGKRGKDVIVKVPWGTRVSYKKTNKLLGDMGIHHKRLMVAKGGRHGLGNGHFKSSLHYCKVLNTNGSTGEFQHLLLELLLIANVGIFGLPNSGKSSFIRIISSAKPKVADYPFTTLVPYLGVVQINNYDRFIIADIPGIIKGASHGLGLGMRFLKHLEHCQILLHFIDIAPVDNSDPLENIITIQHELSNYNENLVRKPCWLIFNKIDLLEQQVAEKRINHVISSLKWKGRYYSISSIHNTNVLSLCNSIMKFIMHHTHS
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF3H_DROME
Sequence: MANRANRHAARTEDSDNTINYVQCDGLAVMKMVKHCHEESSNMDLAQGALLGLVVDKCLEITNCFPFPKSGDETMDEEMYQLTVMRRLRRVNVDHLHVGWYQSSDVGNSLSMALLESQYHYQTSIEESVVVVYDTQKSSRGFLCLKAYRLTPQAIQMYKDGDFTPEAFRTLKVGYENLFAEIPIVIKNSPLTNIMMSELNELLPEDKGHNFLDLGTATVLENQMRSLIERVDELYQEAVRYNKYQQVVFKQDTEKHRALAKLAAENAVRTSKGEPTVPEEEVIKQFRPMTAPNRLTATITSGQINTHAQHIAQFCSQSLAKLFITESLQIAKEAKETK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h, Eukaryotic translation initiation factor 3 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL32_TROWT
Sequence: MAVPKRKKSRANTRARRSQWKASVPGFARLEERGRPVFYLPHRARRILDSNGNELFMEYKGRRVG
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: SET9_GIBZE
Sequence: MAPSQTANKKPRMTLAQVSAYDDILTDALVDHVFYWTTVPKNRTSYHPSRGVKEEEISKILQEEVVLKKDLDSAEKRLLTTNGLKRFHNGLKTDKEKDDFRKHLRRYVQIYLPDCPWEVSSTNRYTIVSHEAAVTARRAIRRNEAIKYLSGVQVVITPEEEMAISSQKKDFSIVVSSRSKCTSLFMGPARFANHDCDANAKLMRTSHAGIEIVATRPIDAGEEITVTYGDNYFGENNCECLCKTCEDLLRNAWEPEEGTVPVQTGIGQSLSDGYSLRRRRRDDSISGSSRTPSVTPDMRPRITKANSRGSLLARDTSSVRSPSIDQTSRKRTHDVLATPPKTPAKRQKLGVQPIVSDSSSRGTSVTASESSGAVETDVTSPEKETPEPMQTPLKGASKKQNNEQSRLAPVSPQSTEGSRSPQQKNGALSSNRSSLDTMSIQAILNDPLESEVESEPESKMKKVTVVPPPVEPVAPIATSIEAVEEGQAADAEQSKRKKQPRRVHKEDTPPARVRTPGDYLLTPLLLSEPEMAWIQCTNCDEYFVQQNAYFTRASCPRCERHSKLYGYIWPKTDKAGPNDKEERILDHRTIHRFLDPDNERRVRNRKSFGASKTNTEEAEDVERGRKRFGTAGLMGRNASTTEDSGHRRSGRLRRVNSRFLDP
What is the function of this protein?
Histone methyltransferase that trimethylates 'Lys-20' of histone H4 to form H4K20me3.
What are the official names of this protein?
Histone-lysine N-methyltransferase SET9, SET domain protein 9.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TG21_GAHVM
Sequence: MDIKYGHVLAYRNVQFYVSECGYKAYFFCGGCLFAVGRPRIDDEYLPELAKIGLVLRGGQSKPLAAHVRRELLRRGMKWAFSSDEDELFIDSIAVLSRDGICSERELCGLLCLETYDPDIAKYMVPTNAISGLTIQAAYDFPHDRTIHIPEFPIITDIYSDLVYECSRDAFVLTCARLTELPKSLSDLVEGLFDGIPTPREALSSEIFGRRVDVIVTAKKAANTTTVQRAWDILQHGCRGKLNVNSNRTNPVQRKKHARFSSFVQIKYIPPVFKIWSCDTSSCMPSTSLNKLWEIFWKVDSVFNMNMLNLNSNLYTENGSQSDLEIIQSELGMISNALFGRHASMFVGVGPENKNISPSQKFLLLQYIHILNRLPNCYDLIRELCDHHTSTIEGECPTAMPDCALADMTNSLFRAILFLGMATEIVVNWMPSSLEEPTSRVPSPSAFADATTLLDVAETSAPKSIQDLKIRKLALILDGLYKDIDPIDVALRESVGEDTAELLCAAIDISVLSAFEHWGYYSRYMQCIISLIDTRLRNSGCITICS
What is the function of this protein?
May facilitate the viral transport through neural circuits.
What are the official names of this protein?
Tegument protein UL21 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL21 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: GSA_YERE8
Sequence: MSKSESLYAQAKQLIPGGVNSPVRAFTGVGGVPLFIERADGAYLFDVDGKAYIDYVGSWGPMVLGHNHPAIRQAVIEAVERGLSFGAPTEMEVKMAELVTNLVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTLGQPNSPGVPADFAKHTLTCTYNDLASVREAFEQYPRDIACIIVEPVAGNMNCVPPLPEFLPGLRALCDKFGALLIIDEVMTGFRVALAGAQDYYNVIPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLTEVAQVGIHETLTELTNLLADGLLDAAKAENIPLVVNHVGGMFGLFFTDAPTVTCYQDVMNCDVERFKRFFHLMLEEGVYLAPSAFEAGFMSVAHSKEDIQKTVDAARRCFAKL
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_PORGI
Sequence: MLNVVSKTIDLGDGRSIKIETGKLAKQADGAVTVTMGNTVLLATVCAAKDANPGCDFMPLQVEYKEKYSAIGRFPGGFTRREGKASDYEILTCRLVDRALRPLFPDNYHAEVFVNVILFSADGEDMPDALAGLAASAALAVSDIPFNGPISEVRVARVDGRYIVNPTFEQLERADIDLMVGATMDNIMMVEGEMDEVQESEMLEGIRVAHEAIKVQCKAQLELSEAVGKLQKREYSHEVNDEDLRKKVHDECYARAYEVATSGTGKHERGEAFEKIVEEFKAQYTEEELAEKAEMIARYYHDVEKEAMRRAILDEGKRLDGRKTTEIRPIWIETDCLPGPHGSAIFTRGETQSLTTVTLGTKSDEKLVDDVLNYTKERFLLHYNFPPFSTGEARPQRGVGRREIGHGNLAHRALKRMIPTDYPYVVRVISDILESNGSSSMATVCAGTLALRDAGVQIRKPVSGIAMGLISENQGKNYAILSDILGDEDHLGDMDFKVTGTKDGITATQMDIKVDGLSYEILENALEQAKQGRLHILGKIMEAQPETRDDLKPHAPRIEKMHIGKEFIGAVIGPGGKIIQGIQEKSGATVNIEEVDGMGVIEISGTNKPCIDAAIGMIKGIVAMPEVGETYPGKITSVMPYGCFVEFLPGKEGLLHISEVDWKRFETIEDTNLKEGESINVKLLDIDPKTGKFKLSRKVLLEKPEGYVEPQPRERRERREGGREGGRNFERRGGDRDHREPRG
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LYPA1_MOUSE
Sequence: MCGNNMSAPMPAVVPAARKATAAVIFLHGLGDTGHGWAEAFAGIKSPHIKYICPHAPVMPVTLNMNMAMPSWFDIVGLSPDSQEDESGIKQAAETVKALIDQEVKNGIPSNRIILGGFSQGGALSLYTALTTQQKLAGVTALSCWLPLRASFSQGPINSANRDISVLQCHGDCDPLVPLMFGSLTVERLKALINPANVTFKIYEGMMHSSCQQEMMDVKHFIDKLLPPID
What is the function of this protein?
Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS (By similarity).  Has depalmitoylating activity toward KCNMA1 (By similarity).  Could also depalmitoylate ADRB2 (By similarity).  Acts as a lysophospholipase hydrolyzing various lysophospholipids including lysophosphatidylcholine (lyso-PC), lysophosphatidylethanolamine (lyso-PE), lysophosphatidylinositol (lyso-PI) and lysophosphatidylserine (lyso-PS)(PubMed:9139730).  Has much higher thioesterase activity than lysophospholipase activity (By similarity).  Contributes to the production of lysophosphatidic acid (LPA) during blood coagulation by recognizing and cleaving plasma phospholipids to generate lysophospholipids which in turn act as substrates for ENPP2 to produce LPA (By similarity).
What are the official names of this protein?
Acyl-protein thioesterase 1, APT-1, Lysophospholipase 1, Lysophospholipase I, LPL-I, LysoPLA I, Palmitoyl-protein hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Nucleus membrane. Endoplasmic reticulum. Note=Shows predominantly a cytoplasmic localization with a weak expression in the cell membrane, nuclear membrane and endoplasmic reticulum.
Protein: SYR_RHOPB
Sequence: MLESVSPPHLFAVMLSRVHAVCEALAAEGALPAGIDLARIVVEPPKDASHGDMATNAAMVLAKEAKAKPRDLAEKIAEKLRADDLVAAVEVAGPGFINLTLQPKVWSEALRTVLADGAGYGRSAVGAGEKVNVEYVSANPTGPMHVGHCRGAVFGDALASLLDFAGYDVTREYYINDAGAQVDVLARSALLRTREALGEEIGEIPEGLYPGDYLKPVGEALAAEYGDKLLAMDEAEWLPIARAKSIAMMMQMIRGDLAALNITHEEFFSERSLIAGDTDRVAATIDFLRGKGDVYEGRLPPPKGAPIEDYEDREQTLFRATAYGDDVDRPLLKSDGSYTYFASDIAYHKTKFDRGFRNMIDVWGSDHGGYIKRVQAAIKAVTGGQGALDVKIVQLVKLLRNGEPVKMSKRSGDFVTLREVVDEVGSDAVRFMMLFRKNDAVLDFDLAKVIEQSKDNAVFYVQYGHARGHSVFRNAREVVPDLPEETVARAAFLADAAVERLTDTAELGLLRQLALYPRIVEAAALAHEPHRIAFYLYELASEFHALWTRGRDLPHLRFIINNDAEITKARLALVQGAVSVLASGLAVLGVHAPDEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPIL3_CRYNB
Sequence: MSVTLHTNLGDIKIELFCESVPRTAENFLALCASGQYDGTLFHRNIRGFMIQGGDPTGTGKGGQSIWGRPFSDEIRQTLRFNNRGMVAMANAGPDTNKSQFFITYAKQPSLDGKYSIFGKVIDGMETLDSMEKTPVNPKSRPLQEIKLLNVTVHANPIADQAKGGLA
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase-like 3, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily.