PharMolix/UniProtQA huggingface dataset:
Protein: GHXQ_ECOLI
Sequence: MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTAFSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLLLIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIAISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTAAGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFIDAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYAGGWAI
What is the function of this protein?
High-affinity transporter for guanine and hypoxanthine.
What are the official names of this protein?
Guanine/hypoxanthine permease GhxQ.
What is the protein family that this protein belongs to?
Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HINT2_MOUSE
Sequence: MAAAVLLAVGLRAARRTLAAAGARGAQVRGNAGVSDGSEVAKAQKAAPGGASPTIFSRILDRSLPADILYEDQQCLVFRDVAPQAPVHFLVIPRKPIPRISQAEEDDQQLLGHLLLVAKKIAQAQGLKDGYRLVVNDGKMGAQSVYHLHIHVLGGRQLQWPPG
What is the function of this protein?
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (By similarity).  Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) (By similarity).  May be involved in steroid biosynthesis (By similarity).  May play a role in apoptosis (By similarity).
What are the official names of this protein?
Adenosine 5'-monophosphoramidase HINT2, HINT-3, Histidine triad nucleotide-binding protein 2, mitochondrial, HINT-2.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PLSY_CHLTE
Sequence: MLTFLAIIVVAYLIGSIPTSIIAGKLLKGIDIREFGSGNAGGTNAFRVLGWKAGLVVTLIDIAKGTIAAVPVVGFFKAHPLGAFPDMNEIALSLIAGMAAVIGHVFTVFAGFKGGKGVSTAAGMLIGIAPVSMLMVIGIFLLAVTISRYVSVGSILAAIAFPLIIAIRKYVFDLGSGLDYRFFDHWFVHDSLDYHLLIFGGIVAVAIIYTHRANIKRLFSGTENRLSFGRKN
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VATD_CHLTR
Sequence: MSSQIKLTKNSYRAEKQKLNMLGMYLPTLKLKKALLQAEVQSAIRLAAESTVTNEQARDRMYAFAELFSIPLYTDAVEQCFSVDILEKDVENIAGVEVPLLKRVVLTSPEYSLLDTPIWLDSLLASVKEYVVSKIYAENAQERLLLLEEELRRVSIRVNLFEKKLIPTTSQTLKKIAIFLSDRSITDVGQMKMAKKKIQQHKE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit D, V-ATPase subunit D.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase D subunit family.
Protein: RUVB_FRATW
Sequence: MIETDRIISANTAQTNDENVIDRAIRPKTLAEYEGQPAVREQMEIFIQAAKARKDALDHTLIFGPPGLGKTTLSNIIANEMGVELKQTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPVVEEILYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLVGATTRAGLLTSPLRDRFGIIQRLEFYSIDDLSKIVYRSAKLLNLDITTDGAMEIAKRSRGTPRIANRLLRRVRDYAQVKGSGVICFEIADKALSMLKVDPVGFDHMDHRYLLTLMEKFAGGPVGLDTMSAALSEEKGTIEDVIEPYLIQQGYIMRTARGRIATLLAYNHFKLKIPDNLSADQQQTLSI
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MED11_CAEBR
Sequence: MELNPVDSILSDRIQAIVATEKNIDDMMKCAREIMQDLGKEKQISKNKMDDNANSFKKLITQVENELSAQMQYLSHVCVGSSHQGSTFGVLQNSLLAQSGLSSLHSELAQILKNIEPPTQEVDEDNEDEEDSGDADMLEETPEDVVAPRTTSSSATTSDGGSGGADDAASSSAPRSQEERRSTEEEEGEQMEN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 11, Mediator complex subunit 11.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RK3_GRATL
Sequence: MKIGLLGKKIGMTQIFDPGGKALPVTILKLGPCLITDIKKMESHGYAAIQIGYVKVNGNKLNKAQIGHLNKYNMPLVKFLKEYKVASTENYQIGKWITVEDLSINQNISVSGTSIGKGFTGCIKRHNFSRGPMSHGSKNHRQPGSIGAGTTPGKVFAGKKMAGRMGGKKVTIQNLKIIDIKINNNLIIVKGSVPGKPGNIVSIYQ
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLYA_CAMC5
Sequence: MSLQSYDKEIFDLVNLELKRQCDHLEMIASENFTYPEVMEVMGSILTNKYAEGYPGKRYYGGCEYVDGIEQLAIDRCKQLFGCEFANVQPNSGSQANQGVYGALLNPGDKILGMDLSHGGHLTHGAKVSSSGKIYESFFYGVELDGRINYERILDIAKIVKPKMIVCGASAYTREIEFDKFRAIADEVGALLFADVAHIAGLVVAGEHQNPFPHCDVVSSTTHKTLRGPRGGIIMTNNEEYAKKINASIFPGIQGGPLVHVIAAKAVGFKHNLSPEWKIYAKQVKANAKKLSEILISRGFDLVSGGTDNHLILMSFLNREFSGKDADIALGNAGITVNKNTVPGEKRSPFVTSGIRVGSPALTARGMKEAEFEIIANKIADVLSDINNTDLQEKIKAELKELAHKFIIYDRATF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUP_COREF
Sequence: MSDRQTQIPAGGGREDDHDDQVQSAGQVQVNTEGVDDLLDEIDGLLENNAEEFVRSYVQKGGE
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: ST7_LOXAF
Sequence: MAEAGTGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHMRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMIDIFCSAEFRDWNCKSIFMRVEDELDIPPAPQSQHFQN
What are the official names of this protein?
Suppressor of tumorigenicity 7 protein.
What is the protein family that this protein belongs to?
Belongs to the ST7 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PAND_ESCF3
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGI2_ARATH
Sequence: MSLQMPIPRKKALTVSHFSITLSLFLAFFISSTSASTNEVSALISWLHSSNSPPPSVFSGWNPSDSDPCQWPYITCSSSDNKLVTEINVVSVQLALPFPPNISSFTSLQKLVISNTNLTGAISSEIGDCSELIVIDLSSNSLVGEIPSSLGKLKNLQELCLNSNGLTGKIPPELGDCVSLKNLEIFDNYLSENLPLELGKISTLESIRAGGNSELSGKIPEEIGNCRNLKVLGLAATKISGSLPVSLGQLSKLQSLSVYSTMLSGEIPKELGNCSELINLFLYDNDLSGTLPKELGKLQNLEKMLLWQNNLHGPIPEEIGFMKSLNAIDLSMNYFSGTIPKSFGNLSNLQELMLSSNNITGSIPSILSNCTKLVQFQIDANQISGLIPPEIGLLKELNIFLGWQNKLEGNIPDELAGCQNLQALDLSQNYLTGSLPAGLFQLRNLTKLLLISNAISGVIPLEIGNCTSLVRLRLVNNRITGEIPKGIGFLQNLSFLDLSENNLSGPVPLEISNCRQLQMLNLSNNTLQGYLPLSLSSLTKLQVLDVSSNDLTGKIPDSLGHLISLNRLILSKNSFNGEIPSSLGHCTNLQLLDLSSNNISGTIPEELFDIQDLDIALNLSWNSLDGFIPERISALNRLSVLDISHNMLSGDLSALSGLENLVSLNISHNRFSGYLPDSKVFRQLIGAEMEGNNGLCSKGFRSCFVSNSSQLTTQRGVHSHRLRIAIGLLISVTAVLAVLGVLAVIRAKQMIRDDNDSETGENLWTWQFTPFQKLNFTVEHVLKCLVEGNVIGKGCSGIVYKAEMPNREVIAVKKLWPVTVPNLNEKTKSSGVRDSFSAEVKTLGSIRHKNIVRFLGCCWNKNTRLLMYDYMSNGSLGSLLHERSGVCSLGWEVRYKIILGAAQGLAYLHHDCVPPIVHRDIKANNILIGPDFEPYIGDFGLAKLVDDGDFARSSNTIAGSYGYIAPEYGYSMKITEKSDVYSYGVVVLEVLTGKQPIDPTIPDGLHIVDWVKKIRDIQVIDQGLQARPESEVEEMMQTLGVALLCINPIPEDRPTMKDVAAMLSEICQEREESMKVDGCSGSCNNGRERGKDDSTSSVMQQTAKYLRSSSTSFSASSLLYSSSSSATSNVRPNLK
What is the function of this protein?
Together with RGI1, RGI3, RGI4 and RGI5, acts as receptor of RGF peptides (e. g.  RGF1, GLV5/CLEL1/RGF2, GLV7/CLEL3/RGF3, GLV3/RGF4, GLV10/CLEL7/RGF5 and RGF10/CLELN), peptide hormones which maintain the postembryonic root stem cell niche by regulating the expression levels and patterns of the transcription factor PLETHORA (PLT, e. g.  PLT1 and PLT2) (PubMed:27229312, PubMed:27229311, PubMed:27001831).  Links RGF peptides signal with their downstream components (PubMed:27229311, PubMed:27001831).
What are the official names of this protein?
LRR receptor-like serine/threonine-protein kinase RGI2, Protein RECEPTOR OF RGF1 3, Protein RGF1 INSENSITIVE 2, Protein ROOT CLAVATA-HOMOLOG1 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PANC_ACIF5
Sequence: MAIFKDIAGLRQWRQSLHGTLALVPTMGNLHEGHLALVRLAANRAEHVLVSIYVNPLQFGPGEDFANYPRTLDQDLQRLHEAGCQTVFTPDDGLMYPRGRQDISIVMPPRSLSKVLCGASRPGHFAGVCTVLSKLLHMVAPEILILGEKDYQQLRIVQQMVADLNLNVQVLPGPLQREADGLAYSSRNIYLNLAERQVAPLLAETLFDLARRSTNDAAVSDLAATGWERLERAGFLPEYLELRDAQTLQSLALPQPGARWFAAARLGQIRLIDNVIIS
What is the function of this protein?
Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
What are the official names of this protein?
Pantothenate synthetase, PS, Pantoate--beta-alanine ligase, Pantoate-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the pantothenate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TI22L_ARATH
Sequence: MNSNIFPPSKQQNELNNIQQSFSNLQSQCSNLLLNVSQTLNPLFNANTNNNKPNIFSALNSFRDQAKQALDSRISRFNSGKAPVWARISDDGGGARAQVTVPIRGSGKGLSADAIEERLAGVPVYALSNSNEEFVLVSGTSSGKSLGLLFCKEEDAETLLKEMKSMDPRMRKEGSKVVALALSKVFQLKVNGVAFRLIPESTQVKNALKERKTAGIDDDDFHGVPVFQSKSLILRSENMSYRPVFFRKEDLEKSLIRASSQQNRLNPALKPGDIQVAVFEDIVKGMRESTTSNWDDIVFIPPGFEVSTEQTQE
What is the function of this protein?
Involved in protein precursor import into chloroplasts.
What are the official names of this protein?
Protein TIC 22-like, chloroplastic, Translocon at the inner envelope membrane of chloroplasts 22-III, AtTIC22-III.
What is the protein family that this protein belongs to?
Belongs to the Tic22 family.
What are the subcellular locations of this protein?
Plastid, chloroplast intermembrane space; Peripheral membrane protein.
Protein: XERC_BIFLS
Sequence: MSSTQFDGDIDSFVSYLKSNRGLSANTLKAYRADLTACLHLFELRGVTDLNEITLDDLRSWMAVESRDHARSSMARKTVAVRGFFAWAYEHGLTATDPAATLMTPSIPSTLPAVLTESQAEQLLDVAEHAVATNQYKDDGGAAAASGSGKAAGKTADKSADTVNRSEAPARADKRDNARVTAESQRNAAILELLYATGIRVAELVSMDIADIDFSNRTIKVTGKGNKQRVVPFGLPAQRALETWLEQGRPVLARTATDAVKSRAANALFLGARGGRIDQRIARDIVHRAAREAGVPDISPHALRHSAATHILDGGADLREVQEMLGHSSLKTTQRYTHVSIEQLKNRYGQAFPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHL12_ARATH
Sequence: MGSIQNTVHYCCVSRDNQIMYAYNNAGDHRNNESLAALCLEKTPPFHKWYFETRGKKTFGFLMKDDFVYFAIVDDVFKKSSVLDFLEKLRDELKEANKKNSRGSFSGSISFSNVQDQIVRRLIASLEFDHTCLPLSSPSIDGAEQSYASNSKAPLLGRSNKQDKKKGRDHAHSLRGIEIEEHRKSNDRGNVTECSNASSESATYVPRRGRSGGSQSIERKWRRQVKIVLAIDIAICLTLLGVWLAICHGIECTRS
What is the function of this protein?
Non-SNARE longin protein involved in membrane-trafficking machinery.
What are the official names of this protein?
Phytolongin Phyl1.2.
What is the protein family that this protein belongs to?
Belongs to the synaptobrevin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: DEGQ_ECOLI
Sequence: MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR
What is the function of this protein?
DegQ could degrade transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions.  DegQ is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for a beta-branched side chain amino acids.  Only unfolded proteins devoid of disulfide bonds appear capable to be cleaved, thereby preventing non-specific proteolysis of folded proteins.  DegQ can substitute for the periplasmic protease DegP.
What are the official names of this protein?
Periplasmic pH-dependent serine endoprotease DegQ, Protease Do.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y190_ADE07
Sequence: MALMRSSWPLRLSITEQRSLSLLKSPEISCPGPVRSSSMMLLSLCPIPPTRSGRTSNSGNRGPVMTSTSSINSSKSWSGTLLPSLIPRCAMQPKHTLSQWRRDAVPTRQSISSTCWALTVQKKTGFPSKSTGRITKNTFSTASCGKRKANRVMTSSRKLSTTVPWMYSSPQSW
What are the official names of this protein?
Uncharacterized 19.0 kDa early protein.
Protein: AROE_SULIK
Sequence: MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFTTLGINAVYLVFDLDEMKFNRIINGLLEIAEGLNVTIPYKEEVMKYLDNTDTYSTRIQAVNTIYKKSGYNTDYLAIKNLVRKKIGNMSGYECYVYGAGGAAKAAAFALSELGCSSISIVNRTNLRANELVELLNKNGYNASIKENCNSTSNIVVVNSTPNPSVVPENCIQKSELVIEFVYKPVETELIKNAKKYGIKYIDGLEILVNQAVEAEKIWFNKSVSDEKIIEYLYARKLVW
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: YL032_YEAST
Sequence: MDNFKIYSTVITTAFLQVPHLYTTNRLWKPIEAPFLVEFLQKRISSKELKNTKAICHIDPSWVNLNASFIRDDMISIKATTDDMDLDAICRISLPLPMNTNDLTAELEKMKRILLDLSEKFNLELIITKEPAYFTPEQTGESKELCIYVHALGFRSNLMECEPQLLAFVDLIKKNGMTLPPQHYIIEPMELNSYSVLPLYMGVDMENFKHISRAFKTSIYAPSLITLSRDLKANPQIFFSGAVHSLSLLARKTLRESISVNSKSFFYRRLTNITPGKLLFIRKYYQQKVNQLILKYQSLIRVTNEYIEFQSISTNLLEMVIKNFTIQVLHEIVEVQISLNENCAMSPELIIDSFFGHTGNQIVVITPKEDSFNQLIVVGNQSSTDEASDTSILHYLSDFIMGSNQVINPNLRQIKAIFEIHPDFEDFISGKKNGKLTRIMELSACLIQLEMEEEDDNLYLNLVSDSFPDFKESFKNVINEFPAEESFFIPEVCHRPIIGTGGSLIQATMRKHNVFIQFSNSFNLPQNKISMIRYDNVIIRCPRKNKANICLAKNDLKQIVQEYDSLQSKTLIRFSSGQYRHILHVNGQKNIIGQIEKNENVYIMIPLKEPLDGTSQLSIQGNDENASRAANELVNSAFGYEYEFKIDQEIDPNKEYEFYNLIVVPFLQIMNIIVTFEKDLITFTFEKDTNENTLTKAIELLSNYLETQKTKIIFKKIIKKFVLGSASSKSNTSNSNTNGNFRSMNNAKSRTTIDNTSQSGASPQRHKMPVITTVGGAQAIKGYIPNTYYNGYGYGYGYTYEYDYNYANSNKAQTNNRHKYQNGRK
What are the official names of this protein?
KH domain-containing protein YLL032C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_SHIDS
Sequence: MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILTEGLPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWAKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RF3_STRPJ
Sequence: MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILGIASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDDIELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNVTQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVELEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LDH_THET8
Sequence: MKVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVRAGSYGDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNPVDVMTQVAYRLSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGDSEVLVWSSAQVGGVPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGKGATYYGIGAGLARLVRAILTDEKGVYTVSAFTPEVEGVLEVSLSLPRILGAGGVEGTVYPSLSPEEREALRRSAEILKEAAFALGF
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_STRSY
Sequence: MSIDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDTDENGFCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVMCNKEIKFKAFLDYAMNLGADYVATGHYAQVTRDEDGTVHMLRGADNGKDQTYFLSQLSQEQLQKTMFPLGHLQKPQVREIAERAGLATAKKKDSTGICFIGEKNFKEFLGQYLPAQPGRMMTVDGRDMGEHTGLMYYTIGQRGGLGIGGQIGGDNEPWFVVGKDLSKNILYVGQGFYHESLMSTSLQASQVHFTRDMPEEFTLECTAKFRYRQPDSQVTVKVKGDKAEVIFAEPQRAITPGQAVVFYDGQECLGGGMIDMAYKDGEACQYI
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSTB_ZYMMO
Sequence: MTNKDNTVEDLEQFIAPPAAENLNLEARNLDFYYGTHQTLFNVSLPVERNKITALIGPSGCGKSTLLRILNRIYALYPQQYAVGRVLLDGKDILTDHDTLTRLKERGDNVTLDPLGDDISQIRARIGMVFQKPTPFPMSIYDNVAYGVRLHFNKSRQELDHIVERSLHRAALWDEVKDKLKESGLSLSGGQQQRLCVARGLAVEPEVLLLDEPASALDPVSTARLEETLMELKKDLSIVIVTHNLQQAARISDYTGFMYLGNMIEFCSTDRLFARPKTRRARDYLTGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.