PharMolix/UniProtQA huggingface dataset:
Protein: HIS8_MYCTO
Sequence: MTRSGHPVTLDDLPLRADLRGKAPYGAPQLAVPVRLNTNENPHPPTRALVDDVVRSVREAAIDLHRYPDRDAVALRADLAGYLTAQTGIQLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIISDGTHTEWIEASRANDFGLDVDVAVAAVVDRKPDVVFIASPNNPSGQSVSLPDLCKLLDVAPGIAIVDEAYGEFSSQPSAVSLVEEYPSKLVVTRTMSKAFAFAGGRLGYLIATPAVIDAMLLVRLPYHLSSVTQAAARAALRHSDDTLSSVAALIAERERVTTSLNDMGFRVIPSDANFVLFGEFADAPAAWRRYLEAGILIRDVGIPGYLRATTGLAEENDAFLRASARIATDLVPVTRSPVGAP
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: TILS_MYCMS
Sequence: MSLFNINKSKKYLIAVSGGPDSVFLLCNIVKLVDPNDLVVCHVNYNFRSDSNNDQMIVTNLCKQLNLKLEILNINKDYSLLKQNFESWARAQRYDFFNMIASKYQIYNLLVAHNLNDLIETYLLQLQRNNLVDYYGLKPVSHYKDLVVYRPLLDIKKSQILNYLNTNKISYAVDSTNSDIKYQRNKIRATLNENNFTKILDQINKANNNLNSIKKIVDNYLKNNIINNELNLTKELFLLDQTCIQRIIYTYFKLINKENLLLNRSNKTISEIVKRLVNSNKNYWKINLNDHSLIKDYNKLFVIKNSLLEPKTIIINDLNDLINQTTFKNIKEIEQIILKDKNFSYVITTDYEMYKSITTIANKKTNRYFIDRKISYKTRLLSPVVYNIKNKIILNKIKKHY
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OSTCN_PIG
Sequence: YLDHGLGAPAPYPDPLEPRREVCELNPDCDELADHIGFQEAYRRFYGIA
What is the function of this protein?
Constitutes 1-2% of the total bone protein.  It binds strongly to apatite and calcium.
What are the official names of this protein?
Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein.
What is the protein family that this protein belongs to?
Belongs to the osteocalcin/matrix Gla protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: GBRA1_PONAB
Sequence: MRKSPGLSDCLWAWILLLSTLTGRSYGQPSLQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLAGGDPGLATIAKSATIEPKEVKPETKPPEPKKTFNSVSKIDRLSRIAFPLLFGIFNLIYWATYLNREPQLKAPTPHQ
What is the function of this protein?
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (By similarity).  Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (By similarity).  The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity).  The alpha1/beta2/gamma2 receptor and the alpha1/beta3/gamma2 receptor exhibit synaptogenic activity (By similarity).  GABRA1-mediated plasticity in the orbitofrontal cortex regulates context-dependent action selection (By similarity).  Functions also as histamine receptor and mediates cellular responses to histamine (By similarity).
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit alpha-1, GABA(A) receptor subunit alpha-1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane.
Protein: GLOD4_MOUSE
Sequence: MATRRALHFVFKVKNRFQTVHFFRDVLGMQVLRHEEFEEGCKAACNGPYDGKWSKTMVGFGPEDDHFVAELTYNYGIGDYKLGNDFMGITLASSQAVSNARKLEWPLSKVAEGIFETEAPGGYKFYLQDRSPSQSDPVLKVTLAVSDLQKSLNYWSNLLGMKIYEQDEEKQRALLGYADNQCKLELQGIQGAVDHAAAFGRIAFSCPQKELPDLEDLMKRESHSILTPLVSLDTPGKATVQVVILADPDGHEICFVGDEAFRELSKMDPKGSKLLDDAMEADKSDEWFATRNKPKASG
What are the official names of this protein?
Glyoxalase domain-containing protein 4.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FTSH_SALTY
Sequence: MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNQDQVREARINGREINVTKKDSNRYTTYIPINDPKLLDNLLTKNVKVVGEPPEEPSLLASIFISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEAKEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVHMRRVPLATDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKIMMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLPEGDAISASRQKLESQISTLYGGRLAEEIIYGVEHVSTGASNDIKVATNLARNMVTQWGFSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQILTDNMDILHAMKDALMKYETIDAPQIDDLMARREVRPPAGWEDPNGTNNSDSNGTPQAPRPVDEPRTPNPGNTMSEQLGDK
What is the function of this protein?
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins.  Plays a role in the quality control of integral membrane proteins.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FtsH.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side.
Protein: EI2BD_RABIT
Sequence: MAAVAVAVREDSGSGMKAELSARPGAGGKEMTQEEKLQLRKEKKQQKKKRKEEKGTDVDTASAVSAAQCPGPAREAPGPGSQSSTPGEKVPAGRTKAELRAERRAKQEAERALKQARKGEQGGPPPQASPSTAGEAPAGGKRLTEHTQADDPTLLRRLVRKSERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQYMSIPSSVIHPAMVRLGLQYSQGLISGSNARCIALLRALQQVIQDYTTPPNEELSRDLVNKLKPYICFLTQCRPLSASMYNAIKFLNKEITGVSSTKREEEAKAELQAAADRYVQEKIVLAAQAILRFASKKISNGDVILVYGCSSLVSRILQEAWSEGRKFRVVVVDSRPRLEGRHMLRFLVRAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCERGDHVALANWQSHPSLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit delta, eIF-2B GDP-GTP exchange factor subunit delta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: BYS_DROME
Sequence: MGKPKKANVATIKNVNLEKQITEGRVAKNKNKDKVKLRAEESANIDARSSQKILAAAKLQQLELDEENFPSLVTVKKVNFSLNDGHVKEDEEVNETDLMADLDMDEDDVAAFERFQQPAQEGKRTLHLSKMIMQKIQEKEADIHTKISDEGSLKIEEIDPKVKEMYEGVRDVLKRYRSGKIPKAFKIIPKLRNWEQILFITEPHNWSAAAMFQGTRIFCSVLSQAMAQRFYNLVLLPRVRDDLCEYKKLNMHLYNALKRALFKPAAFMKGIILPLLEGGDCTLREAIIFGSVVARSSIPVLHSSACLLKICEMAYSGANSIFIRYFLDKRYALPYRVVDAAVFHFLRFENDKRELPVLWHQSLLTFAQRYKNDISSEQRDALLQLLKKKSHFKITPDVRRELQAASCRDVEMMETDNGLAGQPAKMYTDADVEYEG
What is the function of this protein?
Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits.
What are the official names of this protein?
Bystin, Protein bys.
What is the protein family that this protein belongs to?
Belongs to the bystin family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CSC1_ARATH
Sequence: MATLQDIGVSAGINILSAFVFFIIFAVLRLQPFNDRVYFSKWYLKGLRSSPARGGAFAQRFVNLDFRSYMKFLNWMPEALKMPEPELIDHAGLDSVVYLRIYWLGLKIFTPIAVLAWAVLVPVNWTNNTLEMAKQLRNVTSSDIDKLSVSNIPEYSMRFWTHIVMAYAFTIWTCYVLMKEYETIANMRLQFVASEARRPDQFTVLVRNVPPDADESVSELVEHFFLVNHPDHYLTHQVVCNANKLADLVKKKKKLQNWLDYYQLKYARNNSQRIMVKLGFLGLWGQKVDAIEHYIAEIDKISKEISKEREEVVNDPKAIMPAAFVSFKTRWAAAVCAQTQQTRNPTQWLTEWAPEPRDVFWSNLAIPYVSLTVRRLIMHVAFFFLTFFFIVPIAFVQSLATIEGIVKAAPFLKFIVDDKFMKSVIQGFLPGIALKLFLAFLPSILMIMSKFEGFTSISSLERRAAFRYYIFNLVNVFLASVIAGAAFEQLNSFLNQSANQIPKTIGVAIPMKATFFITYIMVDGWAGVAGEILMLKPLIMFHLKNAFLVKTDKDREEAMDPGSIGFNTGEPRIQLYFLLGLVYAPVTPMLLPFILVFFALAYIVYRHQIINVYNQEYESAAAFWPDVHGRVIAALVISQLLLMGLLGTKHAALAAPFLIALPVLTIGFHHFCKGRYEPAFIRYPLQEAMMKDTLETAREPNLNLKGYLQNAYVHPVFKGDEDDYDIDDKLGKFEDEAIIVPTKRQSRRNTPAPSIISGDDSPSLPFSGKLV
What is the function of this protein?
Acts as an osmosensitive calcium-permeable cation channel (PubMed:24503647, PubMed:30382939).  Specifically conducts cations including Ca(2+), K(+) and Na(+) in vitro.  Inactivation or closure of the channel is calcium-dependent (PubMed:24503647).  Mechanosensitive ion channel that converts mechanical stimuli into a flow of ions (PubMed:30382939).
What are the official names of this protein?
Calcium permeable stress-gated cation channel 1, AtCSC1, Hyperosmolality-gated Ca2+ permeable channel 1.2, AtOSCA1.2.
What is the protein family that this protein belongs to?
Belongs to the CSC1 (TC 1.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SYT_ALTMD
Sequence: MPVITLPDGSQRAFDNPVSVLDVANDIGPGLAKATIAGKVNGELVDAVDMIDADAQLQIITAKDEEGLEILRHSCAHLLGHAIKQLWPNTKMAIGPVIDNGFYYDVDMEESLTQEDLAKLEKRMLELAKTNYNVVKNKVSWQEARDAFEARGESYKMEILDENISKDDRPALYQHEEYTDMCRGPHVPNMKFCHHFKLMKVAGAYWRGDSDNKMLQRIYGTAWADKKQLKSYLQRLEEAEKRDHRKIGKALNLFHWQEEAPGMVFWHNDGWSIYTELESFVRKKLREYGYDEVKGPLMMDRSLWEKSGHWDKYAENMFTTESEKREYAVKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGCCHRNEPSGALHGLMRVRGFTQDDAHIFCTEEQILEEVSGCIKMVYETYAAFGFENIKVKLSTRPEKRVGADEIWDKSEAALAEALKANDIEFDYQPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDFSMPGRLGSTYVAEDGERKVPVMIHRAILGSLERFIGILTEEFAGFFPLWLAPQQVVVMNITDKQADYASDCVKKLQDLGFRAKSDLRNEKIGFKIREHTLKRIPYMLVVGDKEMEAGEVAVRSRRGDDLGKMGLEDFIAMAQQEVVEKTIK
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS25_BRABE
Sequence: MPPKKDTKGDSKKGQKAKAGSGGGKAKKKKWSKGKVRDKLNNLVLFDKATYDKLYKEVPSYKLITPSVVSERLKIRGSLARAALKELHSKGMIKLVSKHSAQVIYTRATKDTDSKIVLRRGHQ
What are the official names of this protein?
40S ribosomal protein S25.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS25 family.
Protein: PRR19_BOVIN
Sequence: MDPGEPAPKPFQQPEKPGRVRRRKTRRERNEALAGSRQPLTYQHPPVASRDPHMVLRNSVAPTAAKLVVITQGRLSRDHRGLFNHEVKSLDVARLLSSESLELGTPALTTKSSPSPGRGQQPSLQSRGKENQVPGGSGPGPPSPPQLPDLEQLLGELQCQLILPRAFPRRNLVQEARDAIVGTLQACHGCVPDLTLVLRGCQPHLPGTDPGALKRQRMTPSWINSPEQAPGEGRQRRRQGTKELTFAVPPTSSTPTVHQVSLAPPKGPWPPPLSSLPSPSGAAWGPPTAFDLLKSIWLVATPPPPRPWGIGPPQLLPQPPSPLLPRSSALDWSPSPPAPLPSLSWMVAQSSPEAWSFPPMRLY
What is the function of this protein?
Promotes meiotic crossing over formation through its interaction with CNTD1 by participating in the crossover differentiation step of crossover-specific recombination intermediates.
What are the official names of this protein?
Proline-rich protein 19.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Co-localized at crossover sites with CNTD1. Localizes on synapsed chromosome only in mid/late pachytene spermatocytes.
Protein: TRUA2_BACHK
Sequence: MNNYKLTIQYDGARFKGWQRLGNNDNTIQGKIESVISEMVGKETEIIGCSRTDAGVHALNQVANFQSDEKLVEHKVKKYLNQYLPNDISITNVEEVHNRFHARYNSKVKTYLYKIWNEEHTNPFMRKYSMHVNKKLNVKSMKEAAKHLVGSHDFTAFSNAKSKKKSMVREVYSLEVMEEAGFVQIRVSGNGFLHNMVRKIVGALIEVGLGQLAAEAIPQILEAKQRNQINCLAEASGLYLENVEF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A 2, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I 2, tRNA-uridine isomerase I 2.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GID8B_DANRE
Sequence: MMSYAEKPEDITRDEWMEKLNNVHIQRADMNRLIMNYLVTEGFKEAAEKFRMESGIEPSVDLDSLDERIKIREMVLKGQIQEAIALINSLHPELLDTNRYLYFHLQQQHLIELIRLRETEAALEFAQTQLAEQGEESRECLTEMERTLALLAFDNPEESPFGDLLNMMQRQKVWSEVNQAVLDYENRESTPKLAKLLKLLLWAQNELDQKKVKYPKMTDLSKGTIEDPK
What is the function of this protein?
Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation (By similarity).  Required for normal Wnt signaling and normal dorsoventral patterning during embryogenesis (PubMed:28829046).
What are the official names of this protein?
Glucose-induced degradation protein 8-B homolog, Two hybrid-associated protein 1 with RanBPM, Twa1.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes in the cytoplasm in the absence of Wnt stimulation and in the nucleus in the presence of Wnt stimulation.
Protein: SYT_ACHLI
Sequence: MIKVTFPDGNIKSYKKGITVLEVAEDISISLAKKIVAAKFNEDLVEISRKLEHDGKLQLLTPKEELSFHVLNHSAAHLMAQAIRKLYPDALFGVGPAIEEGYYYDVDFKDSVFTDADLEEVEKMMKKLSEENHLIERIEVSYDEARDIFKNDPYKLELIEVYKDDQLSVYRQGEFIDLCRGGHVPSTKYIKHFKLLSIAGAYWRGDAKNRQLVRVYGIAYFEKAELDKHLVMLEERKLRDHRKIGKDLDIFMTSQEVGSGLPFWLPKGATIRRIIERYITDKELELGYLHVYTPIMANVEFYKQSGHWDHYHENMYPPMDLGDGEMLVLRPMNCPHHMMIYKKDIHSYRELPIRFAELGMMHRYEKSGALSGLQRVREMTLNDAHIFVRPDQIKEEFMRVVHLIIEVYKDFKITDYSFRLSYRDPENKEKYFDDDQMWQRAESELKNVMDEMKLPYKEAIGEAAFYGPKLDIQVRTAMGMEETLSTVQLDFLLPERFDLTYVGEDGKNNHRPVVIHRGVVSTMERFVAYLIEEYKGSFPLWLAPVQLKLIPVNLDLHKDYVMNLHEQLKKLGFRVESDFRNEKLGYKIREAQTLKIPYQLVVGDNEMNTHSITYRPYGSEKQINISIDGFIKLLNERMINKD
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_BURM1
Sequence: MKTAQELRVGNVVQIGSDAWVISKTEYNKSGRNAAVVKLKMKNLLTNAGQESVYKADDKFDVVMLDRKEVTYSYFADPMYVFMDADYNQYEVEAEMMGDALNYLEDGMACEVVFYNEKAISVELPTILVREITYTEPAVKGDTSSGKVLKNAKLATGFELQVPLFCNTGDKIEIDTRTHEYRSRA
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDSA_CHESB
Sequence: MIPNPRVEIGQAVFANDAPLALIAGPCQLESREHAFEMAGRLKEMAEKLGLGFVYKTSFDKANRTSLLGKRGAGLDAALPIFADLRRELGVPVLTDVHTEGQCEILADAVDVLQIPAFLCRQTDLLVAAAKTGKVVNVKKGQFLAPWDMKNVVAKITASGNPNVLTTERGVSFGYNTLVTDMRALPIMAEIGAPVIFDATHSVQQPGGQGSSSGGDRRFVETLARAAVAVGVAGVFIETHQDPDNAPSDGPNMVQLDKMPALLERLMAFDRIAKSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIFK_NEOFI
Sequence: MRPDGPRDPVAGPDSGPEPPYPVRLSGPVIKGFGRGSKELGIPTANIPAEGLAEYPDLQVGVYYGVVALDPAKFQYQEDQGEGSTSSTGGAGAGAGAAILPAVLSIGYNPFYKNKTKSIEIHIMPPLSSPSPTAEGAGEVKFHKLPDFYGTQLKLLILGYIRPEYDYVSLEALIEDIRVDCEVARKSLQRPAYACYIDGDEKECSDAVREQRRWLVNF
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.
What are the official names of this protein?
Riboflavin kinase, Flavin mononucleotide kinase 1.
What is the protein family that this protein belongs to?
Belongs to the flavokinase family.
Protein: RS4_RHIL3
Sequence: MSKRESSKYKIDRRMGENIWGRPKSPVNRREYGPGQHGQRRKGKLSDFGVQLRAKQKLKGYYGDLREKQFRAIFAEADRRKGDTSENLIGLLESRLDAIVYRAKFVPTVFAARQFVNHGHVSVNGVRVNIGSYRCKAGDVIEVREKSKQLVIVLEAVSLAERDVPDYIEVDHNKMVATFGRVPTLSDVPFPVVMEPHLVVEFYSR
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RL7_LAWIP
Sequence: MSVTKEQVIEFISNMTVLELSQFIKELEEKFGVSAAAPAVGMMMAAPTAASAEAEAEEKTEFDVILKEAGANKIAVIKVVRALTGLGLKEAKDKVDGAPSTLKEGVSKEDAEEAKKQLTEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ZDH16_MOUSE
Sequence: MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKVCLRSLLYNSFGGSDTAVDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCVLPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKCIYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGSWDLFREAYAAIETYHQTPPPTFSFRERITHKSLVYLWFLCSSVALALGALTMWHAVLISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFLGVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV
What is the function of this protein?
Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 (PubMed:26644582).  Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (PubMed:26644582).  Also required for eye development (PubMed:26644582).  Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function (By similarity).  May play a role in DNA damage response (PubMed:27159997).  May be involved in apoptosis regulation (PubMed:12021275).  Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity).
What are the official names of this protein?
Palmitoyltransferase ZDHHC16, Abl-philin 2, Zinc finger DHHC domain-containing protein 16, DHHC-16.
What is the protein family that this protein belongs to?
Belongs to the DHHC palmitoyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GUAA_BACVZ
Sequence: MTKLVNEMILVLDFGSQYNQLITRRIREFGVYSELHPHTLTAEEIKEMNPKGIILSGGPNSVYDEGSFRCDEKIFELDIPVLGICYGMQLMTHYLGGKVEAASQREYGKANIQIQGTPDLFKDLPEEQVVWMSHGDLVVEVPEGFTVDATSHHCPNSAMSKADKNWYGVQFHPEVRHSEYGNDLLKNFVFGVCDCEGKWSMENFIEIEMQKIRETVGDKQVLCALSGGVDSSVVAALIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFNMNVIKVDAKDRFLNKLKGVSDPEQKRKIIGNEFIYVFDDEADKLKGIDYLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGLPDDIVWRQPFPGPGLGIRVLGEVTEEKLEIVRESDAILREEVANHGLERDIWQYFTVLPDIRSVGVMGDARTYDYTIGIRAVTSIDGMTSDWARIPWDVLEVISTRIVNEVKHINRVVYDITSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: FEN12_PARTE
Sequence: MGIHQLMQFLKEKAPNCFRTLMLDYFAGRTIGCDASMAMYQFLIQTQSAGLTQIIELTDKEGNRTGHLVGLFNRTLQFLENGIKPVWVFDGKPPLLKSGELARRKKLKEEAKVKTELALEQGDMQQALLQNQRTTTISSIMKEDAIKMLQLMGCPVIIAPCEAEAQCAELCRAGKIYATATEDMDALTFRTPVLLRGFNTKKEPIYEIIYDDMIKELELTYEQFVDLCILCGCDYTEKIEGIGPGTAYKLIKEYKSIEGILEHVQKVNAEREKNNQNPKYTVPSKFLYQDSRELFITPLVQKGDELQLTWNKPDVDNLKKFLIEEKGFAESRIDNGLKRIAKKDPAGFQSRLENFFGKTTKIIHPNNSKAKAKSNKKTEQPQKSGGKKKI
What is the function of this protein?
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair.  During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.  It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation.  Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap.  Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions.  Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity.  Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
What are the official names of this protein?
Flap endonuclease 1-2, FEN-1-2, Flap structure-specific endonuclease 1-2.
What is the protein family that this protein belongs to?
Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
Protein: TPIS_SOLUE
Sequence: MRKPVMAGNWKMYKTPAETIAFFEKFRPLVEKSSHCEIVICPPFTNLAAAVDAVRGTSIRVGAQNVGWAKEGAFTGEVSGPMLNAMGVSHVIIGHSERRQYFNETDETVLKRTQAALEFGLTPIVCVGELLADREGGRTEAVLAGQFQKGIAGLTEQQFAKIVIAYEPVWAIGTGKTATPEIAADTHRAIRGQVREKFGKEAADAVRILYGGSVKPDNAKVLMGQPEIDGVLVGGAALDPVSFASIVNF
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUNW_PECPM
Sequence: MWLRRKQIVRKLTLGVVTTMLGMSLSFSALSATPVETHGQLSIENGRLVDEQGKRVQLRGISSNGLQWVGDYVNKDSMKWLRDDWGINVFRVAMYTAENGYIANPSLANKVKEAVAAAQGLGVYIIIDWHTLSDNDPNTYKAQAKIFFAEMAGLYGNSPNVIYEIANEPNGSVTWNGQIRPYALEVTDTIRSKDPDNLIIVGSGTWSQDIHDAADNQLPDPNTLYALHFYAGTHGQFLRDRIDYAQSRGAAIFVSEWGTSDASGNGGPFLPESQTWIDFLNNRGISWVNWSLSDKSETSAALVAGASKSGGWTEQNLSTSGKFVREQIRAGAGLSGGDTPTMPTEPTNPGNGTTGDIVLQYRNVDNNPSDDAIRMAFNIKNTGSTPIKLSDLQVRYYFHDDGKPGANLFVDWANVGPNNIVTSTGTPAASTDKANRYVLVTFASGAGSLQPGAETGEVQVRIHAGDWSNVNETNDYSYGPNVTSYTNWDKITVHDKGTLVWGTEP
What are the official names of this protein?
Endoglucanase 6, Cellulase V1, Endo-1,4-beta-glucanase V1, Endoglucanase V1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: MNHE2_STAEQ
Sequence: MKQVVLNIVIAFLWVLFQDEDEFKFTTFFAGFLIGLIVIYILHRFFGEEFYLKKIWVAIKFLAVYLYQLITSSISTINYILFKTNEVNPGLLTYETSLKSNWAITFLTILIIITPGSTVIRISKNTNKFFIHSIDVSEKDKENLLKSIKQYEDLILEVTR
What are the official names of this protein?
Putative antiporter subunit mnhE2, Mrp complex subunit E2, Putative NADH-ubiquinone oxidoreductase subunit mnhE2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.