PharMolix/UniProtQA huggingface dataset:
Protein: T68_TERSU
Sequence: MATSGRLLCLCLVLGLIFESLGHPVMGEKRAGENASPSARSLPKRLGNVEAPCGNQTCQFGCCEDDVCRELNCEHVDFPNY
What are the official names of this protein?
Teretoxin Tsu6.8.
What is the protein family that this protein belongs to?
Belongs to the teretoxin M (TM) superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PXPA_STRCO
Sequence: MIDLNADLGEGFGRWTLTDDDALLSVVTSANVACGFHAGDPSVMRRVCDLAAERGVRIGAQVSYRDLAGFGRRAMDVPSDELAAEVAYQIGALRVFAEAAGAPVAYVKPHGALYNRTVHDEGQARAVVAGVRLAGGALPVLGLPGSRLLTAAAEAGLTGVPEAFADRAYTAEGSLVPRSEAGSVVTDEDAVVRRALAFAVEGSVEAVDGTAVAVAARSLCVHGDTPNAARIAARVREALETAGVGIGAFA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: Y3181_METBF
Sequence: MYINPKEILETIQMVRMEHLDIRTVTMGISLRDCSHPDIEVFNENIYEKITTRAKELVRTTNEIQSLYGIPIINKRISVTPIAVAAESCRAPDFVSIAKTMDEAAKDAQVDFIGGFSALVHKGATVGDLKLINSIPEALKSTEKVCSSINVATTKTGINMDAVGLMGSIIKKTADLTADRDGIGCAKLVVFANAPEDNPFMAGAFHGIGEPECVINVGVSGPGVVNAAIRELENPNLTEISETIKKTAFKITRMGEMVGREVSRRLGVEFGILDLSLAPTPAIGDSVAAILEAMGLERCGAHGTTAALALLNDAVKKGGAMASSSVGGLSGAFIPVSEDAGMIEAVRAGALNLEKLEAMTSVCSVGLDMIAVPGDTPASTLSAIIADEMAIGVINRKTTAVRVIPAPGKRVGDSVEFGGLLGNAPIMPLSNFSSETFVKRGGRIPAPIQSLTN
What are the official names of this protein?
UPF0210 protein Mbar_A3181.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: SEPF_STRSY
Sequence: MALKDTFKNLFNYFEVDEVNEVEEQADAYSMPNDRPKMRVANTTVAPVREQQPKVETRREARSESQLQRLHERQQELMTNNNEKEIVKTTIDIKFPKRYEDAPEMVNLLLDNASILIDFQYMSEQQARRCLDYLDGARSVLSGNLKKVSNTMWLLTPVNVTVNIEELRNAGTTTGVADSNFEFDIKR
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: GACF_DICDI
Sequence: MKTHKKKKSLGGLFSHSSSSPNLKSFLTEEVIHEQQQQQQQHNNNNNNNNNHQRQPSTTSTSSYIDSASSSIEETSGYLSKTSSSSSLPSSPLHNQNQNQNGNIQLNSSSGSLNNNEQQQQQQSISQTSSPNTSSPIMGKKKPSRLAQAFKRVKNNGNNKLKKEIEELTNKTGLNQQYTHSNLPFNVVESDIDNGSSGGTTSSTGNIISHSKSPSSSSSSSSSKKHQRKSRFIEPISQSTEDYTDIPRIIKMSVEYLFEKCLLVPGIFRESANAMELQRLSQLFEKGGDIDLSEYTDPHCIGGLLKLYFREKPIPIFPYDLHKRIYSVLNEEDSNIKVKSLLESGLGKGQFLILRYLFELLNAVSINCNVNFMNYQNLAICFAPSLIQSFDLSCYDVIERLIENYHSIFGVVVPVVDNSSNVSSSSLAHPIIGGKSETNVSLNNLTVTILDHGDINNNSNSSNNNNSSSSSSPYKKSPKPSPKSSPKLNNRNSISPKLSSSTSFRKSINLSSNSIMISDEVQQEQQNQQQQQDEQQDEQQDEQQDEQQDEQNSNSTSINTSSSSITRPRKGSTVQYLNRINTCRRPSSWTNNNRIKQQQHHHHHHQQQQQHQQHQQQQSSSSESNSSLTSSPQKRLNSVNGLESYEEGKNVNEIYSSLKEESSKLPKKSSLNRQMTIVNSNNIGNGDEKNSDCTTSDEDEELKISKPIIRSTSVNEILKETNDDNNNNDQINNSNSSNNIPKTTITTTTNNTTTTNNISPIVKSKSQIITSSAKVTPTPTPAPMQTSSFLSTKQTNSPSSSSSPSSTVSSTSSSPSSSLSSSIDNKTMSNVNYNRFQPANRTVSSPNVRNFSVPTTTTTTSIGSNSFVSPRFIGKRTTPSIFSPRKQSICKPKNTTSSLSSSSSNISKSTNSTPTPTPAPILTSTLSVNSTSSSSKLQEKALPTKTTFITQTSSPLLLPQPLTSTSTSTSTSTSTSTSTSTSTSTTIPTPTPTTSSFKSNSFSTSNDNSNNNNNNNNNNNNNNNNNNNNNNNNNNVTSPTIVSSPSSPTSPISPTSSTFIKGHSHSNSLSQTPSSSSSSLGNRLTAPGRQLNHTNSTSSLISKFNQIDTPSGINQGWKGGVVVQKKQDPVKKSLAIFEKE
What is the function of this protein?
Rho GTPase-activating protein involved in the signal transduction pathway.
What are the official names of this protein?
Rho GTPase-activating protein gacF, GTPase activating factor for raC protein F.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BH137_ARATH
Sequence: MATFSYFQNYPHSLLDPLLFPTPHSSINLTSFIDQNHLYPLPNISTVEDISFLEYNVDKTENSGSEKLANTTKTATTGSSSCDQLSHGPSAITNTGKTRGRKARNSNNSKEGVEGRKSKKQKRGSKEEPPTDYIHVRARRGQATDSHSLAERVRREKISERMRTLQNLVPGCDKVTGKALMLDEIINYVQTLQTQVEFLSMKLTSISPVVYDFGSDLDGLILQSEMGSPEVGTSFTNAMPTTTPIFPSLLDNSVVPTHAQVQEEGEERENFVDRSGFNNNNFCSFP
What are the official names of this protein?
Transcription factor bHLH137, Basic helix-loop-helix protein 137, AtbHLH137, bHLH 137, Transcription factor EN 89, bHLH transcription factor bHLH137.
What are the subcellular locations of this protein?
Nucleus.
Protein: FIBA_LAMVI
Sequence: TDPDADKGEFLAEGGGVR
What is the function of this protein?
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix.  Fibrin has a major function in hemostasis as one of the primary components of blood clots.  In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization.  Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.  However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo.  Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway.  Maternal fibrinogen is essential for successful pregnancy.  Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage.  May also facilitate the immune response via both innate and T-cell mediated pathways.
What are the official names of this protein?
Fibrinogen alpha chain.
What are the subcellular locations of this protein?
Secreted.
Protein: DXS_FUSNN
Sequence: MNEELTQRCEEIRKNLIEVVSKNGGHLGSNLGVVELTVCLDEIFDFKEDIVLFDVGHQAYIYKILTDRAERFDSIRTRKGLSPFLDPNESSYDHFISGHAGTALPAAVGFAIANPDKKVIVVVGDASISNGHSLEALNYIGYKKLENILIIVNDNEMSIGENVGFISKFLKKVISSGKYQNFREDVKSFINRIKADRVKRTLERLERSIKGYVTPFYALESLGFRFFNVFEGNNIEKLLPMLKKIKDLKGPTILLVKTEKGKGYCFAEEDKEKFHGIAPFNIETGNTYKSLVSYSEVFGNKILELGKEDENIYTLSAAMIKGTGLHKFSEEFPERCIDTGIAEGFTVTLAAGLAKSGKKPYVCIYSTFIQRAISQLIHDVSIQNLPVRFIIDRSGIVGEDGKTHNGIYDLSFFLSIQNFTVLCPTTAKELGQALEISKNFNLGPLVIRIPRDSIFDIENEEPLEIGRWKVIKKGSKNLFIATGTMLKIILEIYDKLQNRGIYCTIISAASVKPLDENYLLNYIKEYDNIFVLEENYVKNSFGTAILEFFNDNGIQKPLHRIALKSAIIPHGKREELLKEERLKGESLIERIEELIYGRKK
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: KGUA_LISIN
Sequence: MTERGLLIVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYFRSREVFEQAIKDGKMLEYAEYVGNYYGTPLEYVEEKLAAGIDIFLEIEVQGAMQVRKAMPEGIFIFLTPPDLSELKNRIIGRGTESMEVVEERMETAKKEIEMMASYDYAVVNDVVSKAVQKIKGIVETEHLKTERVIHRYKKMLEGLQ
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F151A_DANRE
Sequence: MEVKEEKSCSIGEGEEAEGKEAKTVLGIFTREQFIMLCVGLGLIALLLIITLTSVFVIAKSDASVDVDMEPFPSDGDMLDFLLQTGEIEEKDGLYATWYHAANSKSEMSKALNSDVMILEADVNVQGHNTVNETNIPIMAHPPDIYSDNTLEEWLDAVLKSKKGVKLDFKSISAVEPSLDLLRAKNQTGINRPVWINADILPGPNVPEFWPVVNASEFFELIQLKFPDVTISPGWKVLYLSIFPNVTYTRSMVEQMYSTIRHLPQKITFPVHALMAKNGWPHLSWLLSQSSRYSLTLWQGKENPTLNDLLFIRDNSNPQRIYYDIYEPVLSQFREAAKIKDRPRRFYPGGDIVDYFRPADSDGLNIQWDTVNDKDSLLSLLEDSPGGMLVIPVKSSDGHPNIPIIDGSEMPLKDCLDLILASTKPWGIYLQIKSQNQLSLSLELLRQAYDIDLLHHPTWVNMDISHGAVHIQGYMTGEEFLRTVDRIFPHVTLAPSWPKEALVEGYTPEMLEPMVQLFHRAWQDVSLQLQAEALDRSETWRLVLVQPRFSLTVEHQTENKDINAGIESLMAIRAANRQRSFYNIPKMYREHITDLSVRK
What are the official names of this protein?
Protein FAM151A.
What is the protein family that this protein belongs to?
Belongs to the FAM151 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ENV_HV1N5
Sequence: MRAKGTRKNYQHLWRWGTMLLGMLMICSAAEQLWVTVYYGVPVWKEATTTLFCASDAKAYDTEVHNVWATHACVPTDPNPQEVVLQNVTENFNMWKNNTVEQMHEDIISLWDQSLKPCVKSTPLCVTLNCTDLTNATYANGSSEERGEIRNCSFNVTTIIRNKIQKEYALFYRLDIVPIDKDNTSYTLINCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNDKKFNGTGPCTNVSTVQCTHGIKPVVSTQLLLNGSLAEGEVVIRSENFTNNAKTIIVQLNKSVEINCTRPNNNTKKGIAIGPGRTLYAREKIIGDIRQAHCNISKAKWNDTLKQIVTKLKEQFRNKTIVFNQSSGGDPEIVMHSFNCGGEFFYCKTTQLFNSTWLFNSTWNDTERSDNNETIIIPCRIKQIINSGRK
What are the official names of this protein?
Truncated surface protein, SU, Glycoprotein 120, gp120.
What are the subcellular locations of this protein?
Virion membrane.
Protein: LOG9_ARATH
Sequence: MHIEHISGETVGEVRIVSDMHERKATMAQEAGAFIALLGERYETMEELLEMITWAQLGIHKKTVGLLNVDGYYNNLLAFFDTGVEEGFIKQGACNIVVSAPSARELMEKMELYTPSHKYIASHQSWKVEPLGDYPLLNENKPQ
What is the function of this protein?
Cytokinin-activating enzyme working in the direct activation pathway.  Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity).
What are the official names of this protein?
Putative cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG9, Protein LONELY GUY 9.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
Protein: PEPQ_ACTP2
Sequence: MKQLFTQHIKRLQQVVQTILETNFLSGLWIHSGTARYHFLDDQTAPFKINPHFNYLFPFPTAENCWLFLDGKNKPTVYFYAPNDYWHTPPVAPTDAFFADEFQWVILQDSQEIAKFIQNPTACTFIGEDENLAESLGFNQINPQKVLNQFHFERSIKSEFEIEAIYQAQFAALKGHQAAKQAFFEGKSEFEINLAYLKASQQSDLNVPYGNIVAINQHSAILHYTQLDYAPNPQQQSFLIDAGATIHGYASDITRTYAADPNSEFAAMIKQMEQYKYRIIDQLTVGVNYLSYHTQMQQWIAEMLYEYDFVRLTPEQIFEEGISRAFLPHGLGHLLGLQVHDAAGFQQNPRGTRKSPPEVYPSLRCTRDLAENMVLTIEPGFYFIDMLLNPLQNSPLARHINWQKIAEFKQFGGIRTEDNIVMRSQGAENLTQKAEIELQLSDH
What is the function of this protein?
Splits dipeptides with a prolyl residue in the C-terminal position.
What are the official names of this protein?
Xaa-Pro dipeptidase, X-Pro dipeptidase, Imidodipeptidase, Proline dipeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family. Bacterial-type prolidase subfamily.
Protein: Y174_BRUAB
Sequence: MTDLREKKRIAFFRGHSAERLAAFALMLKGFRIVARRYRTRLGEIDLIARRGDLVLIVEVKARASFEAAQFAVTPQAMRRIEAAADLWLQRQTDRARLSLRFDMVAVLPRRWPKHVPAFFTAGHYG
What are the official names of this protein?
UPF0102 protein BruAb1_0174.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: HYFD_ECOLI
Sequence: MENLALTTLLLPFIGALVVSFSPQRRAAEWGVLFAALTTLCMLSLISAFYQADKVAVTLTLVNVGDVALFGLVIDRVSTLILFVVVFLGLLVTIYSTGYLTDKNREHPHNGTNRYYAFLLVFIGAMAGLVLSSTLLGQLLFFEITGGCSWALISYYQSDKAQRSALKALLITHIGSLGLYLAAATLFLQTGTFALSAMSELHGDARYLVYGGILFAAWGKSAQLPMQAWLPDAMEAPTPISAYLHAASMVKVGVYIFARAIIDGGNIPHVIGGVGMVMALVTILYGFLMYLPQQDMKRLLAWSTITQLGWMFFGLSLSIFGSRLALEGSIAYIVNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLHTLPLPGVGFCVAALAITGVPPFNGFFSKFPLFAAGFALSVEYWILLPAMILLMIESVASFAWFIRWFGRVVPGKPSEAVADAAPLPGSMRLVLIVLIVMSLISSVIAATWLQ
What is the function of this protein?
Possible component of hydrogenase 4.
What are the official names of this protein?
Hydrogenase-4 component D.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HIS7_BACC3
Sequence: MRESSQIRETTETKIKLSLQLDEGKNVSVQTGVGFFDHMLTLFARHGRFGLQVEAEGDVFVDAHHTVEDVGIVLGNCLKEALQNKEGINRYGSAYVPMDESLGFVAIDISGRSYIVFQGELTNPKLGDFDTELTEEFFRAVAHTANITLHARILYGSNTHHKIEALFKAFGRALREAVERNAHITGVNSTKGML
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL16_RUMCH
Sequence: MLMPKRVKHRRVHRGRMTGKATRGNFVSNGEFGIQAMEPAWITSNQIEAARIAMTRFIKRGGKVWIKIFPDKPVTKKPAETRMGSGKGSPEYWVAVVKPGRVLFEIAGVPEETAREALRLAMHKLPVKCKFVTRETEMGGEANES
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: NLRX1_MOUSE
Sequence: MRWGCHLPRTSWGSGLGRTPQLPDEHISFLIQWSWPFKGVHPLRPPRAFIRYHGNSADSAPPPGRHGQLFRSISATEAIQRHRRNLTEWFSRLPREERQFGPTFALDTVHVDPVIRESTPDELLRPSTELATGHQQTQAGLPPLALSQLFDPDSCGRRVQTVVLYGTVGTGKSTLVRKMVLDWCYGRLPAFELLIPFSCEDLSSLGSTPASLCQLVTQRYTPLKEVLPLMTAAGSRLLFVLHGLERLNLDFRLAGTGLCSDPEEPGPPAAIIVNLLRKYMLPEASILVTTRPSTISRIPSKYVGRYGEICGFSDTNLQKLYFQLRLNQPDCGYGAGGASVSVTPAQRDNLIQMLSRNLEGHHQIAAACFLPSYCWLVCATLHFLHAPTPAGQTLTSIYTSFLRLNFSGETLDSTHTSNLSLMSYAARTMGKLAYEGVSSRKTYFSEEDVRGCLEAGIKTEEEFQLLQIFRRDALRFFLAPCVEPGHLGTFVFTVPAMQEYLAALYIVLGLRKTALQRVGKEVVEFVGRVGEDVSLVLGIVAKLLPLRILPLLFNLLKVVPRVFGRMVSKSREAVAQAMVLEMFREEDYYNDDVLDQMGASILGVEGPRRHPDEPSEDEVFELFPMFMGGLLSAHNRAVLAQLGCPIKNLDALENAQAIKKKLGKLGRQVLPPSELLDHLFFHYEFQNQRFSAEVLGSLRQLNLAGVRMTPLKCTVVASVLGSGRHPLDEVNLASCQLDPAGLHTLMPVLLRARKLGLQLNNLGPEACRDLRDLLLHDQCQITTLRLSNNPLTAAGVGLLMDGLAGNTSVTHLSLLHTDLGDEGLELLAAQLDRNKQLQELNVAYNGAGDTVALALAKAAREHPSLELLHLYFNELSSEGRQVLRDLGGSGEGGARVVASLTEGTAVSEYWSVILSEVQRNVHSWDPLRVQRHLKLLLRDLEDSRGATLNPWRKAQLLRVEGEVKTLLEQLGGSGH
What is the function of this protein?
Participates in antiviral signaling (PubMed:35651602).  Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH (RIG-like helicase)-MAVS interaction (By similarity).  Instead, promotes autophagy by interacting with TUFM and subsequently recruiting the autophagy-related proteins ATG5 and ATG12 (By similarity).  Regulates also MAVS-dependent NLRP3 inflammasome activation to attenuate apoptosis (By similarity).  Has no inhibitory function on NF-kappa-B signaling pathway, but enhances NF-kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species (By similarity).  Regulates viral mediated-inflammation and energy metabolism in a sex-dependent manner (PubMed:35651602).  In females, prevents uncontrolled inflammation and energy metabolism and thus, may contribute to the sex differences observed in infectious and inflammatory diseases (PubMed:35651602).
What are the official names of this protein?
NLR family member X1.
What is the protein family that this protein belongs to?
Belongs to the NLRP family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane.
Protein: GLUCL_ANGRO
Sequence: HAEGTYTSDVSSYLQDQAAKEFVSWLKTGR
What are the official names of this protein?
Glucagon-like peptide, GLP.
What is the protein family that this protein belongs to?
Belongs to the glucagon family.
What are the subcellular locations of this protein?
Secreted.
Protein: SYR_BARHE
Sequence: MNVFKNFEKKIKKSLESSDIKGKNGEDLDLSKITVDPPRDSSHGHLSTNAAMVLAKSTGLNPRALAEKIIELLKNDPSVESINVAGPGFINIKLTKPFWQDLIKSMLEKGISYGRIPMGQGKRINVEYVSANPTGPMHVGHCRGAVVGDVLSNLLQFVGYNITKEYYINDAGKQIEVLAHSVLLRYREALGQKINEIPEGLYPGEYLIPLGQSLAQEFGDKLLTIDKEEALSIVKERAIHEMMSMIRKDLAALNIYHDIFFSERMLYADNARAIRNTINDLTLKGYIYKGKLPPPKGQNTEDWEPCEQTLFRSTDVGDDQDRVLIKSDGSYTYFAADVAYFRDKFNRHFDEMIYILGADHAGYVKRLEAMAKAISNDKAKLSVFLCQLVKLFRNGHPVRMSKRAGSFVTLRDVVEEVGSDPVRFMMLYRKCEAPLDFDFAKVTEQSKDNPIFYVQYASARCHSVFRQAQETLCIENISNDKIIEHLNRLTDDNEIFLIRKLSEYPRIIEQAVVHKEPHRLAFYLYDLASSFHTHWNKGSDNLNLRFIQPDDRNLSFARLGLIQAIMNILSSGLAIVGIKAATEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGSA_STAEQ
Sequence: MNIPNQITVFRVILIPFFILFALVDFGFGQISILGGNHIRIEILISAIIFVVASLSDFADGYLARKWQLVTNMGKFLDPLADKLLVASALIVMVQLGFTNSVVAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAIIWILLGDPFVHYLRFPIGVWLLYIGVFFTILSGIEYFYKGRDVFKHSK
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TF3A_SCHPO
Sequence: MCHFNELSIEIESKNLRSAKKIFHCPYEECGKKYSRPSLLEQHLRTHSNERPFVCDYTGCSKAFYRKSHLKIHKRCHTNVKPFSCHYDGCDAQFYTQQHLERHIEVHRKPKPYACTWEGCDECFSKHQQLRSHISACHTHLLPYPCTYQDCELRFATKQKLQNHVNRAHEKIISYSCPHESCVGHEGFEKWSQLQNHIREAHVPSCSICGRQFKTAAHLRHHVVLHQTTLEERKTYHCPMEGCKKSFTRSSALKKHISVIHEGNMAFHCDSCGTKFGYKHMLQRHLERGTCKKAHKPYINECGIKHDGIEGVAIHDQKEKELSSNLVSDVAKKIINEVTGHGYKEAREYSCSFPECNYRFKRLYDMHRHLNSHH
What is the function of this protein?
Is required for correct transcription of 5S RNA genes by RNA polymerase III.  Also binds the transcribed 5S RNA's.  Initiates transcription of the 5S ribosomal RNA gene.
What are the official names of this protein?
Transcription factor IIIA, TFIIIA.
What are the subcellular locations of this protein?
Nucleus.
Protein: CLPX_RHOP2
Sequence: MSKVGTSDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSLVKSRDGIPTPKEICKVLDDYVIGQNHAKKVLSVAVHNHYKRLNHQTKHNDVELAKSNILLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIISARGRSTSIGFAAQVLAPEDRRTGEIFRHVEPEDLLKYGLIPEFVGRLPVVATLEDLDEASLKKILTDPKNALVKQYQRLFEMENIELTFADEALGAVARKAIERKTGARGLRSILESILLETMFDLPGLEGVEEVVISREVVDGTARPLYIYADRSDRAAESSASA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CATC_MOUSE
Sequence: MGPWTHSLRAVLLLVLLGVCTVRSDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVHLKKLDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHTAISYCHETMTGWVHDVLGRNWACFVGKKVESHIEKVNMNAAHLGGLQERYSERLYTHNHNFVKAINTVQKSWTATAYKEYEKMSLRDLIRRSGHSQRIPRPKPAPMTDEIQQQILNLPESWDWRNVQGVNYVSPVRNQESCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQDFGVVEESCFPYTAKDSPCKPRENCLRYYSSDYYYVGGFYGGCNEALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPIPKL
What is the function of this protein?
Thiol protease.  Has dipeptidylpeptidase activity.  Active against a broad range of dipeptide substrates composed of both polar and hydrophobic amino acids.  Proline cannot occupy the P1 position and arginine cannot occupy the P2 position of the substrate.  Can act as both an exopeptidase and endopeptidase.  Activates serine proteases such as elastase, cathepsin G and granzymes A and B.
What are the official names of this protein?
Dipeptidyl peptidase 1, Cathepsin C, Cathepsin J, Dipeptidyl peptidase I, DPP-I, DPPI, Dipeptidyl transferase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome.
Protein: RSMA_LEGPC
Sequence: MRHSPRKRFGQNFLQDKYIINEILRAINPLADDNMLEIGPGLGALTQPLLQKLNRLTAIEIDTDLQNYLTRLPVSQGKLNLIPADALTVDFCQFGPHLRVVGNLPYNISTPLLIYLLKFITCIDDMHFMLQKEVVERIAATHGTKAYGRLSVMLQYHCEVEYLFDVPPEAFEPKPKVDSAIVRLTPYRVSPFESVNTEKLENIVAKAFAMRRKTLTNNLKGIISLSQLNDLGIDGGKRPEQISVAEYVQLAKFISN
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRMC_PROMA
Sequence: MSFERFFSAEEILIWRKQELSKGGRAVDLDWLLDIGGGLGWSTLQELKIFQSSFHKLDLSLEELSLIWMRHLSDQIPLQHLVGKCPWRDFELKVNSSALIPRQETEILIDIALKKVDAGLMKYGRWADLGTGSGALAVALARALPLWEGHAADCCNDALALAESNINTLTENANVSLHLGDWWEPLKPWWGNFDLVVANPPYIPKTHLSELDPVVRDHEPILALSGGDDGMDSCRKVIKGAMKGLRSGGWLLLEHNFDQSEQALNLMVDSGFLEVDFENDLEGVRRFGLALRP
What is the function of this protein?
Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.
What are the official names of this protein?
Release factor glutamine methyltransferase, RF MTase, N5-glutamine methyltransferase PrmC, Protein-(glutamine-N5) MTase PrmC, Protein-glutamine N-methyltransferase PrmC.
What is the protein family that this protein belongs to?
Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
Protein: SIGA_SYNY3
Sequence: MTQTKEPLTKAESAELEQEIELSQYINTDDIDDDDIDVEDLEQEVAATEGKEKKVRKIRKDAVKKKPYTEDSIRIYLQEIGRIRLLRAEEEIELARQIADLLELELIRDNLTLQLERQPSELEWGKQVWKLETAKQRLVGDKKKEPKKKDIDSYLANPDNELSLENEWSQQPNKNFAAFRRRLFLDRRAKDKMVQSNLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTIRLPVHLYETISRIKKTTKLLSQEMRRKPTEEEIAEKMEMTIEKLRFIAKSAQLPISLETPIGKEEDSRLGDFIEADGETPEDEVSKNLLREDLENVLDTLSPRERDVLRLRYGLDDGRMKTLEEIGQIFNVTRERIRQIEAKALRKLRHPNRNSILKEYIR
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor SigA.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPC35_MYCTU
Sequence: MIYLETSALVKLIRIEVESDALADWLDDRTELRWITSALTEVELSRAIRAVSPEGLPAVPSVLARLDRFEIDAVIRSTAAAYPNPALRSLDAIHLATAQTAGSVAPLTALVTYDNRLKEAAEALSLAVVAPGQAR
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  An RNase (By similarity).  Upon expression in M. smegmatis inhibits colony formation.  Its toxic effect is neutralized by coexpression with cognate antitoxin VapB35.
What are the official names of this protein?
Ribonuclease VapC35, RNase VapC35, Toxin VapC35.
What is the protein family that this protein belongs to?
Belongs to the PINc/VapC protein family.
Protein: PLSX_CYAP4
Sequence: MGATRARIAVDAMGGDHAPDQIVAGALRAREELEVEVLLVGDPDQIHSAVKHHNNSSAIEIVPAEGVIEMHEEPLSGIKRKPRASINVAMNLVKEKQADAVVSAGHSGAAMAAALLRLGRLPGIDRPAIGAVLPTLIPGKAVLILDVGANVDCRPKFLEQFALMGTIYSQYVLGVEKPQVGLLNIGEEECKGNDLALRTYEILKENTQIPFVGNAEGRDVLSGQFDVIVCDGFVGNVLLKFAEAVGEVALQILREELPRGLHGQVGTALLKPNLRRIKQRMDHAEHGGGLLLGVNGVCIISHGSSQAPSIFNAIRLAKEAVDHQVSDRIQASCRLTANPVVDGN
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.