PharMolix/UniProtQA huggingface dataset:
Protein: RRAA_SHISS
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL438_MIMIV
Sequence: MDYKQSNLFLFPIGLGSTYIFYKKICGTFCSIDNDLEVNPYLTHGILMLTLVYFLSDYYLMIVKYNPKHNVYFVHHFIGIVSIYFSYMKYYYLIKYLFAYLTFELSTPFLNIAIKYRNQGVYNKCSIFSELAFFILFTVVRIIFGTYLWFVTSNTLSSIEYPYNYLIVLPTILQFLNYWWYYRILKILRAKLFGCINKED
What are the official names of this protein?
Putative TLC domain-containing protein L438.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NCKPL_MOUSE
Sequence: MSLTSAYQLKLAEKLTILNDRGQGVLIRMYNIKKTCSDSKSKPPFLLEKSMESCLKYINKKFPNIDVRNSTQHLGPVHREKAEIIRFLTNYYQSFVDVMEFRDHVYELLNTIDACQCHFDINLNFDFTRSYLDLIVTYTSVILLLSRIEDRRILIGMYNCAHEMLHGHSDPSFARLGQMVLEYDHPLKKLTEEFGPHTKAVSGALLSLHFLFVRRNQGAEQWRSAQLLSLISSPPAMINPANSDTMACEYLSVEVMERWIIIGFLLCHGCLNSNSQCQKLWKLCLEGSLYITLIREDVLQVHKVTEDLFSSLKGYSKRVADIKESKEHAITNSGQFHCQRRQFLRTAVKELETVLNDEPGLLGPKALFAFMALSFIRDEVTWLVRHTENVTKTKTPEDYADSSIAELLFLLEEIRALVRRHIKVIQQYHLQYLARFDVLVLSDIIQNLSVCPEEESVIMSSFVSILSSLNLKQVDNEEKFDFSGLRLDWFRLQAYTSVSKAPLHLHENPDLAKVMNLIIFHSQMLDSVEKMLVETSDLSTFCFHLRTFEKMFATTLEEPTMLRYTIAFPLICAHFVHCVHEMCPEEYPHLKNHGLHHCNSFLEDLAKQTSNCVLEICAEQRNLNEQLLPKHCATTISKAKNKKSMKQRQAPRKGEPERDKPGAESHRKNRSLVTNMDKLHLNLTELALAMNHVHSFSVFEHTIFPSEYLSSHLEARLNRAIVTLAGYNATTQEILRPSELLAGVKAYISFIQSLAQFLGADASRIVRNALLQQTQPLDSSGEQTVTTLYTNWYLESLLRQASSGAIVLSPAMQAFISLPRDGEQNFSAEEFSDISEMRALAEILGPYGMKFLSENLMWHVTSQIVELKKLVVENMDILVQIRSNFSKPELMASLLPQLTGAENVLKRMTIIGVILSFRAMAQEGLQEVFSAHCPFLMGPIECLKEFVTPDTDIKVTLSVFELACAAGVSCDIDPALVAAIANLKADNSSPEEEYKVACLLLIFLAVSLPLLATDPSSFFSIEKDGYNNNIHCLTKAIIQVSAALFTLYNKNIETHLKEFLVVASVSLLQLGQETDKLKTRNRESISLLMRLVVEESPFLTLDMLESCFPYVLLRNAYREVSRAFYLNRLPASSH
What is the function of this protein?
Essential hematopoietic-specific regulator of the actin cytoskeleton.  Controls lymphocyte development, activation, proliferation and homeostasis, erythrocyte membrane stability, as well as phagocytosis and migration by neutrophils and macrophages (PubMed:19015308, PubMed:23424621).  Component of the WAVE2 complex which signals downstream of RAC to stimulate F-actin polymerization (PubMed:23424621).  Required for stabilization and/or translation of the WAVE2 complex proteins in hematopoietic cells (PubMed:19015308).  Within the WAVE2 complex, enables the cortical actin network to restrain excessive degranulation and granule release by T-cells.  Required for efficient T-lymphocyte and neutrophil migration (By similarity).  Exhibits complex cycles of activation and inhibition to generate waves of propagating the assembly with actin.  Also involved in mechanisms WAVE independent to regulate myosin and actin polymerization during neutrophil chemotaxis (By similarity).  In T-cells, required for proper mechanistic target of rapamycin complex 2 (mTORC2)-dependent AKT phosphorylation, cell proliferation and cytokine secretion, including that of IL2 and TNF (By similarity).
What are the official names of this protein?
Nck-associated protein 1-like, Hematopoietic protein 1.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein. Cytoplasm. Note=Localizes to the leading edge of polarized neutrophils.
Protein: TSAD_BACLD
Sequence: MNHKKDLYVLGIETSCDETAAAIVKNGTDIISNVVASQIESHKRFGGVVPEIASRHHVEQITIVLEEAFAQADMTFDDIDAIAVTEGPGLVGALLIGVNAAKALSFARGIPLVGVHHIAGHIYANRLVQDIQFPAIALVVSGGHTELVYMKEHGSFEVIGETLDDAAGEAYDKVARTMGLPYPGGPHIDKLAQKGEANVPLPRAWLEEGSYHFSFSGLKSAVINTLHNASQKGETIAPEDLSASFQESVIDVLVTKTERAAEAYGVKQVLLAGGVAANKGLRAALEKTFSSRPEIELLIPPLSLCTDNAAMIAAAGTVAFEKGIRGKYDMNGQPGLDLTSY
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LOLD_ANADE
Sequence: MAEPVATPTVELSGVRKDYVAGPVVTPVLHGVDLTVGAGEFTALMGPSGSGKSTLLNLIGLLDRPTGGRVRVAGLDTAALDDDAMARTRGRTIGFVFQFHHLLPAFTALENVMIPMMAARGRAAPDMAECGEHLLRQVGLGAVLHRRATQLSGGQQQRVAIARALAMAPRLVLADEPTGNLDTHAADEVFALLREFNRRAGITFLIVTHDPRLADRCDRIVELVDGRIVADGPHRRSGA
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IF1_YERPE
Sequence: MAKEDNIEMQGTVLDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GGPP8_ARATH
Sequence: MATTVHLSSFSLFIQSRGRRDNSISSVKSLKKRTGLSPSSALTSQGGRDMIPPQGKSNDHNSAFDFKLYMIRKAESVNAALDVSIVPLREPLTVQEAVRYSLLAGGKRVRPLLCIAVCELVGGDEATAMSAACAVEMIHTSSLIHDDLPCMDNADLRRGKPTNHKVFGEDMAVLAGDALLALAFEHMTVVSSGLVASERMIRAVVELARAIGTKGLVAGQVVDLSSERLNPHDVGLERLEFIHLHKTAALLEAAAVIGAIMGGGTEEEIEKLRKYARCIGLLFQVVDDILDVTKSTEELGKTAGKDVMAGKLTYPRLIGLERSREVAEKLSREAEEQLLGFESDKAAPLVALASYISCRND
What is the function of this protein?
Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate.
What are the official names of this protein?
Putative geranylgeranyl pyrophosphate synthase 8, chloroplastic, GGPP synthase 8, GGPS8, (2E,6E)-farnesyl diphosphate synthase 8, Dimethylallyltranstransferase 8, Farnesyl diphosphate synthase 8, Farnesyltranstransferase 8, Geranyltranstransferase 8.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CCG7_HUMAN
Sequence: MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWRRGRSPSDISSDVSIQMTQNYPPAIKYPDHLHISTSPC
What is the function of this protein?
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (PubMed:21127204).  Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).  Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization.  Displays subunit-specific AMPA receptor regulation.  Shows specificity only for GRIA1 and GRIA2 (PubMed:21172611).
What are the official names of this protein?
Voltage-dependent calcium channel gamma-7 subunit, Neuronal voltage-gated calcium channel gamma-7 subunit, Transmembrane AMPAR regulatory protein gamma-7, TARP gamma-7.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PLAK_RAT
Sequence: MEVMNLIEQPIKVTEWQQTYTYDSGIHSGVNTCVPSVSSKGLLDEDDTCGRQYTLKKTTTYTQGVPQSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLENVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIPINEPYADDMDATYRPMYSSDVPLDPLDMHMDMDGDYPMDTYSDGLRPPYPAADHMLA
What is the function of this protein?
Common junctional plaque protein.  The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue.  The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques.  Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells.  Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
What are the official names of this protein?
Junction plakoglobin.
What is the protein family that this protein belongs to?
Belongs to the beta-catenin family.
What are the subcellular locations of this protein?
Cell junction, adherens junction. Cell junction, desmosome. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Cytoplasmic in a soluble and membrane-associated form.
Protein: MSRB_ECOBW
Sequence: MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: DAPF_VIBC1
Sequence: MHFHFSKMHGLGNDFMVVDCITQNVFFSQDLIRRLADRHTGVGFDQLLVVEAPYDPETDFHYRIFNADGSEVEQCGNGARCFARFVRLKGLTNRYSISVSTKKGKMILDVEDDGEVTVNMGVPEFEPNKIPFKAKQKEKTYIMRAGDKTLFCGAVSMGNPHVVTVVDDVDTAEVETLGPLLESHERFPERVNAGFMQVVNRNHIRLRVYERGAGETQACGSGACGAVAVGILQGLLDENVKVSLPGGDLRISWQGPGKPLFMTGPATHVFDGQLSC
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_RHIME
Sequence: MSEGVDLKELKRRMDGAIAAFKHDIASLRTGRASANVLDPVTVEAYGSRMPLNQVANITVPESRMLSVSVWDKSMVGAVERAIRESNLGLNPIVDGQNLRIPLPELNEERRKSLVKVAHDYAEKSKVAVRHVRRDGMDDLKKAEKDGEIGQDESRAQSERVQKMTDDVISEIDRLLAEKEKEIMQV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AGAS_ECOLI
Sequence: MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNFLEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALLMPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDETLVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA
What is the function of this protein?
Catalyzes the isomerization-deamination of galactosamine 6-phosphate to form tagatofuranose 6-phosphate and ammonium ion.
What are the official names of this protein?
Putative D-galactosamine-6-phosphate deaminase AgaS, Gam-6-P deaminase/isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. AgaS subfamily.
Protein: PSBD_BPSYP
Sequence: MTSSTLSQPIKQRGWFDVLDDWIKRDRFVFVGWSGLLLFPTAYLALGGWLTGTTFVTSWYTHGLASSYLEGANFLTAAVSTPADAMGHSLLLLWGPESQGDIVRWFQLGGLWTFVALHGAFSLIGFMLRQFEISRLVGIRPYNAIAFSGPIAVFVSVFLMYPLGQSSWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLYEDGEQSNTFKAFEPTQEEETYSMVTANRYWSQIFGIAFSNKRWLHFFMLFVPVMGLWTSSIGIIGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGLRAWMAPVDQPHENFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Host cellular thylakoid membrane; Multi-pass membrane protein.
Protein: PSRP_ECOUT
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: PAO_ORYSJ
Sequence: MPVMAPTASLLLSPRPLPASRRVPSLPALSASGRLRLRRARADTRLRVAAPPSVPGEADQAPGETEPSTSSADEKFVWRDHWYPVSLVEDLDPSVPTPFQLLNRDLVIWKDPKSGEWVALDDRCPHRLAPLSEGRIDETGCLQCSYHGWSFDGSGACTRIPQAAPEGPEAKAVRSPKACAIKFPTLVSQGLLFVWPDENGWEKATATKPPMLPKEFEDPAFSTVTIQRDLYYGYDTLMENVSDPSHIEFAHHKVTGRRDRARPLPFKMESSGAWGYSGSNSGNPRISATFVAPCYALNKIEIDTKLPIFGDQKWVIWICSFNIPMAPGKTRSIVCSARNFFQFSMPGKAWWQLVPRWYEHWTSNLVYDGDMIVLQGQEKIFLSASKESSADINQQYTKITFTPTQADRFVLAFRAWLRKFGNSQPDWFGNPSQEVLPSTVLSKREMLDRYEQHTLKCSSCKGAYNAFQTLQKVFMGATVAFCATAGIPADVQFRLLLAAAALVSAAVAYAFYTLQKNFVFVDYVHAEID
What is the function of this protein?
Catalyzes the key reaction of chlorophyll catabolism, porphyrin macrocycle cleavage of pheophorbide a (pheide a) to a primary fluorescent catabolite (pFCC).  Works in a two-step reaction with red chlorophyll catabolite reductase (RCCR).  Creates the intermediate RCC through the opening of the porphyrin macrocycle by the introduction of one atom of molecular oxygen at the alpha-methine bridge.  Seems to be specific for pheide a.  Belongs to the chlorophyll catabolic enzymes (CCEs) (By similarity).  May play a role in senescence and response to wounding (PubMed:21807436).
What are the official names of this protein?
Pheophorbide a oxygenase, chloroplastic, OsPaO, Pheide a oxygenase.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RSSA_MAGO7
Sequence: MAPANLPSVFNATSQDIEMLLAAQSHIGSKNLQVHMAPYLWKTRQDGVNVINVGKTWEKIVLAARIITAIDNPADVCVISARPYGQRAVLKFAAHTGAQAIAGRFTPGSFTNYITRSFKEPRLIVVTDPRTDAQAIKEASYVNIPVIALCDTDSPTEYVDVAIPTNNKGRHAIGCIWWMLAREVLRLRGTIYNRETPWDVMVDLYFYRDPEAEAEDKVEEEKLAGVEEVGPAAIESGFATGGGDWEATAPAAASGWDDAAAQPQNWDSAAQGAASWDEAAAPKEGQW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIMT_ENT38
Sequence: MVSQRVQALLNQLRTQGIADERVLEAIAQVPREKFVDEAFEHKAWENVALPIGQGQTISQPYMVARMTELLELTPESRVLEIGTGSGYQTAILAHLVHHVCSVERIKGLQWHARRRLKQLDLHNVSTRHGDGWLGWQARAPFDAIIVTAAPLEIPAALLSQLDNGGILVLPVGDEHQLLKRVRRRDGEFIIDTVEAVRFVPLVKGELA
What is the function of this protein?
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues.  It plays a role in the repair and/or degradation of damaged proteins.
What are the official names of this protein?
Protein-L-isoaspartate O-methyltransferase, L-isoaspartyl protein carboxyl methyltransferase, Protein L-isoaspartyl methyltransferase, Protein-beta-aspartate methyltransferase, PIMT.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDIPT_RAT
Sequence: MPEENIFLFVPNLIGYARIVFAIISFYFMPCCPFTASSFYLLSGLLDAFDGHAARALNQGTRFGAMLDMLTDRCATMCLLVNLALLYPRATLLFQLSMSLDVASHWLHLHSSVVRGSESHKMIDLSGNPVLRIYYTSRPALFTLCAGNELFYCLLYLFNFSEGPLVGSVGLFRMGLWITAPIALLKSIISVIHLVTAARNMAALDAADRAKKK
What is the function of this protein?
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction.  May thus act to reduce an excessive cellular PtdIns content.  The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.
What are the official names of this protein?
CDP-diacylglycerol--inositol 3-phosphatidyltransferase, Phosphatidylinositol synthase, PI synthase, PtdIns synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: RPPH_SHEWM
Sequence: MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQYPQGGVDDGETPEEAMYRELYEEVGLRPEHVQILTSTRSWLRYRLPKRLIRQDSKPVCIGQKQKWFLLQLKSSESAINLNACGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPTALPFQSREHHSNNRRGRRR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: HSLV_YERE8
Sequence: MTTIVSVRRNGHVVIGGDGQVTLGNTVMKGNAKKVRRLYNNKVIAGFAGGTADAFTLFELFERKLEMHQGHLTKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPEDDLIAIGSGGPYAQSAARALLENTELGARDIVEKSLSIAGDICIYTNRFQTIEELTY
What is the function of this protein?
Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
What are the official names of this protein?
ATP-dependent protease subunit HslV.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family. HslV subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG2_LEGPL
Sequence: MFKRTIPLFAAFTLAISPSIFPNYAHAQEDKPKTNQYWWPKMLDLSPLRQPNATSNPMGEKFNYAEEFNSLDLNAVIEDLKKLMTTSQDWWPADYGNYGPLFIRMSWHAAGTYRIYDGRGGANGGFQRFAPQNSWPDNANLDKARRLLWPIKQKYGRKISWADLLVLAGNVAMESMGFKTIGFAGGREDAWEAININWGTEGKWLESKRQDKVGKLEKPLAATVMGLIYVNPEGPNGVPDPLAAAEKIRETFGRMAMNDEETVALIAGGHAFGKTHGAASGKYLGPAPEAAGIEEQGFGWKNSYGSGKGKDTITSGLEGAWTVTPTHWSHNYLQNLFNFNWVKTKSPGGAIQWVPENSNASSMVPDAFDPSKRHAPVMLTTDLALKFDPVYSKIAKRFLDNPKEFDDAFARAWFKLIHRDMGPRSRYLGSLVPKEIMIWQDPVPPVDYKLVDANDIANLKGKILNSGLTTPELVKTAWASASTFRGTDMRGGANGARIRLAPQKDWPANDPQELAKVLKTLESIQNNFNNAQADGKKISLADLIVLGGNAAIEQAAKQAGYDIIVPFTPGRTDATQGMTDVKSFEVLEPKADGFRNYFDKSNNMSPPEMLVDKASLLKLSVPEMTVLVGGMRVLNANTGQNQYGVFTDKPGTLNNDFFINLLSMSTEWKKSSETEGIYEGYDRKTGKLKWKATSVDLIFGANSELRAVAEAYATDDAKDKFIQDFVNAWVKVMTADRFDIKAANANINS
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase 2, CP 2, Peroxidase/catalase 2.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: MTNA_ECOLU
Sequence: MNIKGKHYRTVWVSGDGKAVEIIDQTKLPFKFEVVALTSAEMAATAIQDMWVRGAPLIGVVAAYGIALGMNHDASDMGLQRYYDLLIKTRPTAINLKWALDRMIDTLKDLCVSERKDVAWALAAEIAEEDVALCEQIGLHGAEVIREIAQKKPAGSVVNILTHCNAGWLATVDWGTALSPIYKAHENGIPVHVWVDETRPRNQGGLTAFELGSHGIPHTLIADNAGGHLMQHGDVDLCIVGTDRTTARGDVCNKIGTYLKALAAHDNHVPFYVALPSPTIDWTIEDGKSIPIEQRDGKEQSHVYGINPQGELSWVNTAPEGTRCGNYAFDVTPARYITGFITERGVCAASKSALADMFADLKSKALQGEQH
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Protein: MSRA_MYCPA
Sequence: MTNTQKAILAGGCFWGMQELIRKQPGVVSTRVGYTGGDVPNATYRNHGTHAEAVEIIYDPAVTDYRQILEFFFQIHDPTTKDRQGNDRGPSYRSAIFYTDDEQKRIALDTIADVEASGLWPGKVVTEVSPAGDFWEAEPEHQDYLQRYPNGYTCHYIRPGWKLPRRATSGS
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.