PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_CHLPB
Sequence: MKGKGEQVFRLESSYEPEGDQPQAIEALRQGVMDGQTNQVLLGVTGSGKTFTMANVIAEVNKPVLLISHNKTLAAQLYGELKQFFPHNAVEYFISYYDFYQPEAYIPTMDKYIAKDLKINDEIERLRLKATSSLLSGRKDVIVVSSVSCIYGLGAPEDWKAQIIELRVNMEKERDSFLQELISLHFVRDDSDLAPGKFRVRGDVIDLVPMHEESALRVEFFGDEIERLQLFDHTTGEIFEDEEYAFIYPARQFVAGREKLQQAMLGIEDELAHRLNVFRSGEKFVEARRIEERTRYDLEMIKELGYCSGIENYSRHLSGRKAGERPYCLLDYFPEDYLVIVDESHVTFPQIRGMYAGDRSRKTILVEYGFRLPSALDNRPLRFEEFETMVPQLISVSATPGDYELRRSGGSVVEQLVRPTGLLDPEIVVRPVNGQIDDLLEEIRKHTGKGFKSLVMTLTKRMSEDLHDYLRKAGLRTRYLHSEIKSLERMQILRELRTGEIDILVGVNLLREGLDLPEVSLVAILDADKEGFLRDSKSLMQIAGRAARNVEGMVVFYADRITASMRYVIDETERRRSVQRKFNEDHGVIPASIVKSVDQVLDTTGVADAEDRFRRRRFGLEQRSRRGIEDLVGSLKREDLYAMAEELRLEMQEAAESMEFEKAAYLRDEVTKLEDAAEEKRESEGGMDSG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHCB_RHOVL
Sequence: MLDAFAKVVAQADARGEFLSNVQLDGLSAMVADGNKRLDAVNAINSNASSIVTSAARALFAEQPQLIQPGGNAYTNRRMAACLRDMEIILRYVSYAAIAGDSSVLDDRCLNGLKETYQALGTPGASVAAGVQKMKEAAIAVANDSSNVTVGDCSALMAEIASYFDRAAAAVA
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex (phycobilisome, PBS).  Phycocyanin is the major phycobiliprotein in the PBS rod.
What are the official names of this protein?
C-phycocyanin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side. Note=Part of the phycobilisome rod.
Protein: CP11A_BOVIN
Sequence: MLARGLPLRSALVKACPPILSTVGEGWGHHRVGTGEGAGISTKTPRPYSEIPSPGDNGWLNLYHFWREKGSQRIHFRHIENFQKYGPIYREKLGNLESVYIIHPEDVAHLFKFEGSYPERYDIPPWLAYHRYYQKPIGVLFKKSGTWKKDRVVLNTEVMAPEAIKNFIPLLNPVSQDFVSLLHKRIKQQGSGKFVGDIKEDLFHFAFESITNVMFGERLGMLEETVNPEAQKFIDAVYKMFHTSVPLLNVPPELYRLFRTKTWRDHVAAWDTIFNKAEKYTEIFYQDLRRKTEFRNYPGILYCLLKSEKMLLEDVKANITEMLAGGVNTTSMTLQWHLYEMARSLNVQEMLREEVLNARRQAEGDISKMLQMVPLLKASIKETLRLHPISVTLQRYPESDLVLQDYLIPAKTLVQVAIYAMGRDPAFFSSPDKFDPTRWLSKDKDLIHFRNLGFGWGVRQCVGRRIAELEMTLFLIHILENFKVEMQHIGDVDTIFNLILTPDKPIFLVFRPFNQDPPQA
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones (PubMed:11412116).  Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal (PubMed:11412116).  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PubMed:11412116).
What are the official names of this protein?
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc).
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: ADEC2_BRADU
Sequence: MRQVMNAIPDDLLITAPDEVRIRQDLVLTALGHRPADRSLRVGRLLDVHSRTWSEDQEIVIKGRRIAWVGPAGSYPGEVRERVHRPDVAAVPGFGEVHKHIESSHLTPEWEAALVLPHGNTWTCEASHEFSNVNGARNLEFWFEARRRGSPLKIFPQPGSAVPPTAYEWGGGWYGRDEQARFMAESLMVTGLDEVMDWPAVWNPDNPSYKRLWGMIEATFAARGVVEGHASGLRDLPSINAFAAAGLASDHEVQTPEETWDKLTRGLFVELRVYAMDEIVRWLLAKGLQDWSQIAFTTDDRSASHTLELGASDHNARLAIEAGLAPEIAIQCLTINPARHMRLTPFVGSLAPGRFGDVVLLSDVGKLTIAEVWADGVQISEGERYIGQVPEIVWPDWATKTVNIKRSIKPQDFELRAEPGRATMKAAVIRPFHWHPEFYTLELPVRDGAVQRDESEAITKFAIVDRFSGDGRIAKMFWRGCGPRTPETAVACSVAHDKHNIWVVGSSDAAMAKAVNALIELQGGWALVREGELVATVRFEVGGLMSCRSAQALDAEMQALYAEGRKVDWMYEPTYRPRWYPGFPERLMFATLTCAPWSWVLVAPCEQAPLGFINVQTGEAHPVIW
What are the official names of this protein?
Adenine deaminase 2, Adenase 2, Adenine aminase 2.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: RL25_DESDA
Sequence: MNIEKTLSVQKREGYGKGPSGRLRAQKLIPGVFYTPKGENISVQAPALPLQKIYEEMGHTTVFNLEIEENGQKTAYPVLIWQVQFHPYKRAFTHIDFYGVDLDKEVTVDVPVEFVGTSRGVKLGGVLETYREMVRLTSKPLNMPQKITVDVTDMGINDTISVGDLKLPENVRAEFDQNYALVTVISKSKDDAEEEGDED
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: LEPA_DEIGD
Sequence: MNVRNFSIIAHVDHGKSTLADRILERLGAMGERDKRDQTLDTLELERERGITIKSTPIRLTYRRANGEEYTFNLIDTPGHVDFGYEVSRSLAACEGVLLLVDASQGVEAQTIVNAYLAIDNNLEIIPVVNKIDLPAADPEGAAQELEEVIGIPAEEAVFASGKTGQGVDQILEAIVERIPPPPGDPQAPLKALIFDSFYDAYQGVILFVRVLEGTLKPKQKIMLFSNGKSFEVDKVGTFSPGLVVGDALSAGAVGWVAASIKDIHDAQVGDTITEKDRPTAEPFPGFKPAQPVVFSGLYPTDTEDYRKLREALEKLKLNDAAFTFEPETSEALGFGFRCGFLGLLHAEIVQERLEREFDLDLIATAPAVVYRVTLTNGEVFETQNPAEFPTRDRIARVEEPYIKLSIMLPEEYVGPVMQLLQERRGNMVTMNYVGKRVELIYEVPFAEILYDFHDRLKSISRGYASMDYEQIGYREGDLRKVDILVNGEVVDALAVIVHEDKAYSLGRKIVDKMAEVIPRQLFPVPVQAAIGGKIIARATVKAYRKDVLAKCYGGDITRKKKLLEKQKKGRARMKQIGTVEVPQEAFLAVLSTEE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: FORD_DICDI
Sequence: MVKLFGKSKKKEESPQSIDIAFQSILDEIGVVETEKKHLMATMDTVRKQQLIQSYSSKKFSKNEFGNKSKKKSIITQSPHYFVDCLKNDPSKEVLTSLRVRLGNQPLKWLKEFLSLDGVSLLIKVLILNEIKQVKNQEDIYKIAQCLHSLKLIMNTKFGLESVIKQPTNIHSISLVMDTPHLKTRIMVIELLAALCVVNSKGLPLVLSAMDNYREVKREKKPFIHLFQGLKNPSGSLQATTFALINTLISSSQSVEERQKIRNQFKKLGITKVIEELEPEYANNPDLATQKDLYEQECRWDEQEQIENARGDISDENPEALVKAILDRTAGGPLYSSFTSILRLLANSITDQTKDQSLSNYLFVEKVIGKMNNGESYLDDIGTFFGGGGGGDGSLDIAHVSGEKAVLIQKEIEDLKKQKKRDQDKLAEKDKLLTKLAKRMRKMEEAIKLGKGLEYLNNQIEIESPPDSSTSTPQETTPGGTKVPLKTSPVTKADLKHKLSTFTTAKAPNGVSDFLSGLDTTNQQGSTDASQTEAGSGDGIPLPPGAPPPPPPPGGKLAPSTPQLCSRPPSIKMKSYQWTRYRTRNVTNTFWKNVNLTKYNDCLPHEQIEGLFGAAIFEKKEKELKKGSEVTVIDTKRAQNIGILLSRFKNVTHDAIYDAIYSLDESILDLETINQFIKYIPSKEEIDCIIAFKQQQEQLPEEERMKLGKSEIFIDKISTIPRLEQRIQALHFKLNFPDKLYHAKPDIRKFNEAFVQLQNNNIFAIMELILSIGNFINFGTNRGNASGFKIDSINKMADTKSNIREKYTLVHYLIELLESTQPELLKVFDEIPSVVDAATLSFNQSSSEIKLLRAGLIKLEKEIFVRQPKSVEPKPDDETINNNGEDDINNTSSDEKTEGQQQRQGEEEENDESESTGNSFADSLKKKKSQVNTNSTSDSKQSLEPLKDDDPLKLKLSEFLLASKTELDDTETLIAETEVLFKSICKFFGEDSTKIQPEEFLAIFKKFNDKFIMSKKDLEIEKSIKDKSTQRKNEKERKEMEIKKSKLEMIHSKLKKIGSPSSSNRILASNESSPTSSTSSVVHQHDDEDEETIKEYINNPSPSQQSNSSEEEGMMDDLLNLIRDGNFRELRRMNLQQKKPVRTKRVIAKQPTRPQALDTPSSTYSSISSIYDAEPLDMSDQEDEDEEEEEDEEEEEEEEEGDDDNDNDEEEGEN
What is the function of this protein?
Formins play an important role in the nucleation of actin and the formation of linear actin filaments.
What are the official names of this protein?
Formin-D, Diaphanous-related formin dia4.
What is the protein family that this protein belongs to?
Belongs to the formin homology family. Diaphanous subfamily.
Protein: TESK1_RAT
Sequence: MAGERPPLRGPGPGETPVEGPGGAGGGPGRGRPSSYRALRSAVSSLARVDDFDCAEKIGAGFFSEVYKVRHRQSGQVMVLKMNKLPSNRSNTLREVQLMNRLRHPNILRFMGVCVHQGQLHALTEYMNGGTLEQLLSSPEPLSWPVRLHLALDIAQGLRYLHAKGVFHRDLTSKNCLVRREDGGFTAVVGDFGLAEKIPVYREGARKEPLAVVGSPYWMAPEVLRGELYDEKADVFAFGIVLCELIARVPADPDYLPRTEDFGLDVPAFRTLVGNDCPLPFLLLAIHCCSMEPSARAPFTEITQHLEQILEQLPEPTPLAKMPLAKAPLTYNQGSVPRGGPSATLPRSDPRLSRSRSDLFLPPSPESPPSWGDNLTRVNPFSLREDLRGGKIKLLDTPCKPATPLPLVPPSPLTSTQLPLVASPESLVQPETPVRRCRSLPSSPELPRRMETALPGPGPSPVGPSTEERMDCEGSSPEPEPPGPAPQLPLAVATDNFISTCSSASQPWSARPGPSLNNNPPAVVVNSPQGWAREPWNRAQHSLPRAAALERTEPSPPPSAPREQEEGLPCPGCCLSPFSFGFLSMCPRPTPAVARYRNLNCEAGSLLCHRGHHAKPPTPSLQLPGARS
What is the function of this protein?
Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues (PubMed:10207045).  Regulates the cellular cytoskeleton by enhancing actin stress fiber formation via phosphorylation of cofilin and by preventing microtubule breakdown via inhibition of TAOK1/MARKK kinase activity (PubMed:18216281, PubMed:11555644).  Inhibits podocyte motility via regulation of actin cytoskeletal dynamics and phosphorylation of CFL1 (By similarity).  Positively regulates integrin-mediated cell spreading, via phosphorylation of cofilin (By similarity).  Suppresses ciliogenesis via multiple pathways; phosphorylation of CFL1, suppression of ciliary vesicle directional trafficking to the ciliary base, and by facilitating YAP1 nuclear localization where it acts as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 (By similarity).  Probably plays a central role at and after the meiotic phase of spermatogenesis (PubMed:8537404).
What are the official names of this protein?
Dual specificity testis-specific protein kinase 1, Testicular protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, lamellipodium. Note=Colocalizes with SPRY4 in vesicular spots in the cytoplasm (By similarity). Localized to F-actin-rich lamellipodia at the cell periphery following fibronectin-mediated cell adhesion of Schwann cells (PubMed:22302232).
Protein: CAP8_ADE05
Sequence: MSKEIPTPYMWSYQPQMGLAAGAAQDYSTRINYMSAGPHMISRVNGIRAHRNRILLEQAAITTTPRNNLNPRSWPAALVYQESPAPTTVVLPRDAQAEVQMTNSGAQLAGGFRHRVRSPGQGITHLTIRGRGIQLNDESVSSSLGLRPDGTFQIGGAGRPSFTPRQAILTLQTSSSEPRSGGIGTLQFIEEFVPSVYFNPFSGPPGHYPDQFIPNFDAVKDSADGYD
What is the function of this protein?
Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.
What are the official names of this protein?
Pre-hexon-linking protein VIII, Pre-protein VIII, pVIII.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae hexon-linking protein family.
What are the subcellular locations of this protein?
[Hexon-linking protein-C]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion. SUBCELLULAR LOCATION: [Pre-hexon-linking protein VIII]: Host nucleus. SUBCELLULAR LOCATION: [Hexon-linking protein-N]: Virion. Note=Located on the inner side of the capsid shell. Present in 120 copies per virion.
Protein: Y532_ALKMQ
Sequence: MILVNTDYISKKELETLTIVKGSTIQSKHLGKDILSGFKTLVGGELTAYSDMMNEARAIATKRMVAEAQGVGADAIINIRYASSAVMGGAAEIMVYGTAVKFV
What are the official names of this protein?
UPF0145 protein Amet_0532.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: PUR1_MYCLE
Sequence: MCLAVGVGVRAPKHVPQIRRLGRAGRRLRCVTNCALGSCPIVTVQQPGRDFSSPREECGVFGVWAPGELVAKLTYFGLYALQHRGQEAAGIAVADGSQVLVFKDLGLVSQVFDEQTLAAMEGHVAIGHCRYSTTGDTTWENAQPVFRNIAAGSGVALGHNGNLVNTAELAARARDAGLIAKRCPAPATTDSDILGALLAHGAADSTLEQAALELLPTVRGAFCLTFMDENTLYACRDPYGVRPLSLGRLDRGWVVASETAGLDIVGASFVRDIEPGELLAIDADGVRSTRFANPTPKGCVFEYVYLARPDSTLAGRSVHGTRVEIGRRLARECPVEADLVIGVPESGTPAAVGYAQESGISYGQGLMKNAYVGRTFIQPSQTIRQLGIRLKLNPLKEVIRGKRLIVVDDSVVRGNTQRALVRMLREAGAVELHVRIASPPVKWPCFYGIDFPSPAELIANVVADEEEMLEAVRQGIGADTLGYISLRGMIAASEQPASRLCYACFDGRYPIELPSEAMLGKNVIEHMLANAARGAGLRDLAADQVPVDADENCVWR
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: METK3_POPTR
Sequence: MAETFLFTSESVNEGHPDKLCDQISDAVLDACLAQDPDSKVACETCTKTNMVMVFGEITTKADVDYEKIVRDTCRNIGFTSADVGLDADNCKVLVNIEQQSPDIAQGVHGHFSKRPEEIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYYNENGAMVPVRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDEKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSIVASGLARRCIVQVSYAIGVPEPLSVFVDTYGTGKIPDKEILQIVKESFDFRPGMISINLDLKRGGNSRFLKTAAYGHFGRDDPDFTWEVVKPLKWDNKVQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 3, AdoMet synthase 3, Methionine adenosyltransferase 3, MAT 3.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1L_PYRAB
Sequence: MEREEIVSFLDEYLSISSYPDKSSNGLQVEGKEEVERIAFAVDACLDTIAKARAFNADMLIVHHGIIWGGVSYVKGLFAKRLKALLSSEMNLYVAHIPLDVHPEVGNNVQLLKLLNLEPLEPFGEYKGIKIGYIGEFEEPKPLPMIAQILAEKLPVDYVRSYEFGLQEIKRVAVVSGAGGFAIEEASEKADLLITGEISHADYRTAEDLRVSVIAAGHYATETLGVKALMKLVREKFGVKTIFIDSPTGL
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: RL16_RHOOB
Sequence: MLIPRRVKHRKQHHPSRSGAAKGGTQVTFGDYGIQALEPAYITNRQIESARIAMTRHIKRGGKIWINIFPDRPLTKKPAETRMGSGKGSPEWWIANVKPGRVMFEMSYPNEEIAREALRRAMHKLPCKCRIVTREEQF
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: PSBC_CARPA
Sequence: MKTLYSLRRFYHVETLFNGTLALAGRDQETTGFAWWAGNARLINLSGKLLGAHVAHAGLIVFWAGAMNLFEVAHFVPEKPMYEQGLILLPHLATLGWGVGPGGEVIDTFPYFVSGVLHLISSAVLGFGGIYHALLGPETLEESFPFFGYVWKDRNKMTTILGIHLILLGIGAFLLVFKALYFGGVYDTWAPGGGDVRKITNLTLSPSVIFGYLLKSPFGGEGWIVSVDDLEDIIGGHVWLGSICIFGGIWHILTKPFAWARRALVWSGEAYLSYSLGALSVFGFIACCFVWFNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVGSAQGPTGLGKYLMRSPTGEVIFGGETMRFWDLRAPWLEPLRGPNGLDLSRLKKDIQPWQERRSAEYMTHAPLGSLNSVGGVATEINAVNYVSPRSWLATSHFVLGFFLFVGHLWHAGRARAAAAGFEKGIDRDLEPVLFMTPLN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SYCE1_RAT
Sequence: MATRPQPLSVEPEGSADLLHGPEGARGRRGSTQKIEDLMEMVEKLQKVGSLEPRIEVLINRINEVQQAKKKASEELGEAQTVWDTLQKEVDSLHEEKVRLKDILNRKEETLRIMQLHCQEKESEAERKHSMLQECKDRISFLNNQIDNEKAKLRRLRLDFEEHLETLMSQHKDTMEFHKPEHLTEEMSVLDSSKEQLLKEEKLIKAKLEDVQHRLCALCGPEGSSTFSDGLFLRSHEAAAAMQMFKDENKKAEELLEAAAQQHQQLQQRCRQLQQKRQRLKEELEKHGVQILAQIQSTQKEEDSSWRTASPKPLEAHKETVQERPSSRT
What is the function of this protein?
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.  Requires SYCP1 in order to be incorporated into the central element.  May have a role in the synaptonemal complex assembly, stabilization and recombination.
What are the official names of this protein?
Synaptonemal complex central element protein 1.
What is the protein family that this protein belongs to?
Belongs to the SYCE family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE2 in the central elements.
Protein: CFC1_CHICK
Sequence: MFWRKHVRILFTVTLIWQAIHLGKGREKEHEKDVKNFNDTAQKQSPKNSVTIIDAFSDMNQSYQSRKQQNSREFVPFTGITESKNLNRNCCQNGGTCILGAFCACPKHFSGRHCELRKCGSIIHGDWVMKGCWLCRCLYGTLKCLSQNTQDGCELRREEEIIRLYSNGLRLQQTMSALICLLTFLLELCCWQL
What is the function of this protein?
May play a role in mesoderm and/or neural patterning during gastrulation.
What are the official names of this protein?
Cryptic protein, Cripto-related factor 1.
What is the protein family that this protein belongs to?
Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted.
Protein: PAX_I56A1
Sequence: MEDFVRQCFNPMIIELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMYSDFHFIDERGESIIVESGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGVEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARVKTRLFTIRQEMASRGLWDSFVSPREAKRQLKKDLKSEEPCVGLPTKVSHRTSPALKTLEPMWMDSNRTAALRASFLKCPKK
What is the function of this protein?
May play a role in the modulation of host immune response.
What are the official names of this protein?
Protein PA-X.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA-X family.
Protein: PPR35_MOUSE
Sequence: MMGFGASALESIEGEEALEVPGPPPEPRAPEPRAPEPEPGLDLSLSPSPLPESPKARKSSPGQRKGRRGGSRRGRQVRFQLAPPSPVRSEPLLVAGAPGDDHELEAPALQSSLALSLELQNARAAVASGQFDASKAVEEQLRKSFRTRCALEETVAEGLNVPRSKRLYRDLVSLQVPEEQVLNAALREKLAMLPPQPRAPPLKEVLGPGPDMTMLCNPDSLWSESPHLTVDGLPPLRLQARPRPSEDTFLMHRMLRRWEA
What is the function of this protein?
During centriole duplication, plays a role in the centriole elongation by promoting the recruitment of the microtubule-binding elongation machinery through its interaction with TTTN, leading to the centriole to centrosome conversion (By similarity).  In addition may play a role in the primary cilia assembly (PubMed:32628936).
What are the official names of this protein?
Protein phosphatase 1 regulatory subunit 35.
What is the protein family that this protein belongs to?
Belongs to the PPP1R35 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Recruited to the nascent daughter centriole early in the duplication cycle and localizes to the proximal centriolar lumen just above the cartwheel. Co-localizes with RTTN at the centriole.
Protein: DOHH_BOVIN
Sequence: MVTEQEVEAVGQTLVDPGQPLQARFRALFTLRGLGGPVAISWISRAFDDDSALLKHELAYCLGQMQDRRAIPVLLDVLRDTRQEPMVRHEAGEALGAIGDPEVLEILKQYSTDPVVEVAETCQLAVRRLEWLQQHGGESAVRGPYLSVDPAPPAEERDLGQLREALLDEARPLFDRYRAMFALRDAGGKEAALALAEGLRCGSALFRHEIGYVLGQMQHEAAVPQLAAALAQPTENPMVRHECAEALGAIARPACLAALRAHVADPERVVRESCEVALDMYEYETGSTFQYADGLERLRSPLS
What is the function of this protein?
Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A.  This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine.  Hypusination is unique to mature eIF-5A factor and is essential for its function.
What are the official names of this protein?
Deoxyhypusine hydroxylase, DOHH, Deoxyhypusine dioxygenase, Deoxyhypusine monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine hydroxylase family.
Protein: KCY_HUMAN
Sequence: MKPLVVFVLGGPGAGKGTQCARIVEKYGYTHLSAGELLRDERKNPDSQYGELIEKYIKEGKIVPVEITISLLKREMDQTMAANAQKNKFLIDGFPRNQDNLQGWNKTMDGKADVSFVLFFDCNNEICIERCLERGKSSGRSDDNRESLEKRIQTYLQSTKPIIDLYEEMGKVKKIDASKSVDEVFDEVVQIFDKEG
What is the function of this protein?
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP.  Plays an important role in de novo pyrimidine nucleotide biosynthesis.  Has preference for UMP and CMP as phosphate acceptors.  Also displays broad nucleoside diphosphate kinase activity.
What are the official names of this protein?
UMP-CMP kinase, Deoxycytidylate kinase, CK, dCMP kinase, Nucleoside-diphosphate kinase, Uridine monophosphate/cytidine monophosphate kinase, UMP/CMP kinase, UMP/CMPK.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly cytoplasmic, less than 15% nuclear.
Protein: TUSD_SALG2
Sequence: MRYAIMVTGPAYGTQQASSALQFAHALLNEGHELASVFFYREGVYNANLLTSPASDEYDLVRAWQKLNTQHGVALNICVAAALRRGIIDETEAGRLELPSANLQPGFTLSGLGALAEASLTCDRVVQF
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Accepts sulfur from TusA and transfers it in turn to TusE.
What are the official names of this protein?
Sulfurtransferase TusD, tRNA 2-thiouridine synthesizing protein D.
What is the protein family that this protein belongs to?
Belongs to the DsrE/TusD family.
What are the subcellular locations of this protein?
Cytoplasm.