PharMolix/UniProtQA huggingface dataset:
Protein: MUTL_GEOSM
Sequence: MATKIRILPENLTNKIAAGEVVERPASVAKELVENALDAGSKEVVVEIESGGRRLIKVSDTGCGMSRDDALLALERHATSKIATDEDLFSLCTLGFRGEALPSVASVSRLTISTRTSDSVEGTEIYAEGGRIKEVKECGMAVGTVISVRNLFFNTPARLKFMKSAETEGGHVGELLTRLAISRPEVRFTYKNDGKVMFRALDADLKERVATMLGRSISSFLYPVSYQEGGLKVSGLVAAPECSRSAGSHLYTYINGRFIKDKVVQHAILQAYRNFLERGRYPVVAVFIDIAPGEVDVNVHPTKHEVRFREQGRVHDAIQKAVESVLKETPWLKRSAVAAASRPAEKGGGALRPFSSMEASQAALPVTPQPRPALTPGHPDPPPQAQLQQPLVSESRVAEVRELLVNFQPRPQPPLRPQYRGSVAPREGSPYAPIAAAPVPASEPQSAAQDSDHVAAGYFSSLGVIGQFNASYILCQRGTDLILIDQHAAHERVAFEKLKGQFAGREVDSQGLLFPETMEFSFRESAVLREHQAELARLGFEFEEFGGNTWLLKGVPQVLSATRYVDTIRDILEELGSLSRSRAFSDIQEDLLARIACHSVVRGKRTLSPVEIAALFKQMDETDFSSNCPHGRPVMQTLTLAEVEKMFKRI
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: YMH2_CAEEL
Sequence: MLKSLLSLVTSGNKEKKKKRSSAGLTGHAPPAADSSFFSEADSSIMNVTSITLPTVSGRDDSIQSTSPVLGYSPFGFVERKNRAASFDFCLSDKPQSDVVVHRRSLQPSTPTPNQSAESSFIENIFDSPGQRNRLHSMIEEKIYEAGSGSPQKFTGRVS
What are the official names of this protein?
Uncharacterized protein F58A4.2.
Protein: IF5_DICDI
Sequence: MAQVNIRRDVEDQFYRYKMEVLQGKVEGKGNGIKTVIVNLPNIARDLDRQPEYITKFFEIEFNAKSNIENEKYSINGQYTVERLASALDKFISKFVLCSFCKNPETKFVIKKGVIEFKCAACGRVGPIDMKHKLTSYIVKNPPKAVSTKSTHDEALAQQPQIKKEKKSKKKKDDDDEEDDVVWFTDTSEKAAEERKKKAIGDSTSAVISMMADISVEPQSAKEEQDEDDEQEEGQEKESDPVSSISSFLETNPADQELMEKLDSVQEEFGLRSSATSKAAIEALCKNAENTIKFVKTQTALLKKISKRRDGKLGILLGFEELCVKDETLLKSIQGILKNLFDAGILTEENILKWYHQKAKSKVVIKACKDFIAWLETAEEEEEDEEEDEEDDS
What is the function of this protein?
Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S. mRNA. Met-tRNA[F]. eIF-2. GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide.  The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S. mRNA. Met-tRNA[F]) (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 5, eIF-5.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: SSRP_XANOP
Sequence: MSKKPTKDKANGAKATKTIALNKRARHEYHLEERYEAGLALQGWEIKAIRAGRANIVDGYAYVRSGEIYLIGAQITPLIQASTHTVPVERRDRKLLLHRAEIDKVLTRVEREGYTLVPTALYWSSNKVKLEIALAKGKQNHDKRDAAKERDWQRDKQRVMRRHNRDA
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: SYT_CAMC1
Sequence: MSDIIAYKLNGEIVDTQSIAGRESSAEPIYFDNSKEALHVIRHSCAHLMAQAIKSLYPKAKFFVGPNVEDGFYYDFRVDDEGTKLGESDLAAIEDKMKELAEKKFDIVKTCSTKANMSEKFKNDDLKQEVLKRIPDGEVSSYAQGDFEDLCRGPHLPNTKFLKFFKLTRVAGAYLGGDESREMLTRIYGTAYADKESLKEHIRIIEEAKKRDHRKLGVEMKLFTFDEEVGGGLPIWLPNGGRLRSKLEQLLYKAHRDRGYEPVRGPELLKADVWRRSGHYANYKENMYFTTIDETEYGIKPMNCVGHIKVYQSDIRSYRDLPLKFFEYGVVHRHEKSGVLHGLFRVREFAQDDSHIFCMPSQIKENILEILKFAGTIMENFGFHYEMEISTKPAKAIGGDEIWDTATKALKEALDENGFKYGIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDFNLPERFDLGYIDANNERQRPVMLHRALLGSFERFIGILLEHTAGELPFFIAPTQVVIVPISDAHLDYAKEISRELRKINVDSEIASKNESLNKRIRTAEKQRVPMIVVLGDNEVANKSVALRDRQARTQSDMSLAEFVNLTKEKLSEVHF
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_BACC7
Sequence: MTKEQIIEAVKSMTVLELNDLVKAIEEEFGVTAAAPVAVAGGAGEAAAEKTEFDVELTSAGAQKIKVIKVVREITGLGLKEAKELVDNTPKVIKEAAAKEEAEEIKAKLEEVGAAVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: U31A_SCYTH
Sequence: MGFAKQFFFLAVLLSAAVMCSMAEPAQERLIESIACIQKGLPCMEHSDCCRGVCEALFCQ
What is the function of this protein?
Probable insect neurotoxin with ion channel impairing activity (Probable).  Does not show activity on 45 human receptors from 9 families (5-hydroxytryptamine, adrenergic, dopamine, muscarinic, histamine, neurotransmitter, opioid, sigma, and gaba(A) receptors) (PubMed:27227898).  In vivo, does not cause paralytic or lethal activity when injected into sheep blowflies (PubMed:27227898).  When mixed with U3-SYTX-Sth1h does not cause paralytic or lethal activity when injected into crickets (PubMed:27227898).  It is noteworthy that both sheep blowflies and crickets are evolutionarily distant from prey species (PubMed:27227898).
What are the official names of this protein?
U3-scytotoxin-Sth1a, U3-SYTX-Sth1a, U3-Sth1a.
What are the subcellular locations of this protein?
Secreted.
Protein: Y092_BUCBP
Sequence: MNKSDSLLSKDLFLLYQEFSEIRKIKQDTVFQSRRFKLVQDIKIKKNMYEQDIHYHYLSCQKFQISFNHDSIFYLRNKNYFDVLKKLKIGKYVPEIILDVHGLNQDQAKRKLGELLNICHKENLFCASVIHGHGRNILKNKIPIWLSRHPSVIAFYKIPKKFGRSTAILFLIHSSD
What are the official names of this protein?
UPF0115 protein bbp_092.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: Y8587_AGRRK
Sequence: MIALDHLRHVNVEAARTARARYRAGTVEPTSGIAPGFTQANMIVLPRDWAFDFLLYAQRNPRACPVLDVSDPGSHTTLLAPGADLRKDLPLYRVWRDGKLAEETTDATAAWGEHPDLVSFLIGCSFTFETPMVEAGIEIRHITDRSNVPMYLTNKACRPAGRLRGNMVVSMRPIPASRVADAATISGRFPAVHGAPVHVGAPEEIGIKDLAKPEFGDPVRIEPGEIPVFWACGVTPQAAVMASGVPFAITHAPGHMFITNIPDSAYHA
What are the official names of this protein?
Putative hydro-lyase Arad_8587.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: PEPC_SUNMU
Sequence: MKWMVVALVCLQLLEAKVTKVTLKKFKSIRENLREQGLLEDFLKTNHYDPAQKYHFGDFSVAYEPMAYMDASYFGEISIGTPPQNFLVLFDTGSSNLWVPSVYCQSQACTGHARFNPNQSSTYSTNGQTFSLQYGSGSLTGFFGYDTMTVQNIKVPHQEFGLSQNEPGTNFIYAQFDGIMGMAYPSLAMGGATTALQGMLQEGALTSPVFSFYLSNQQGSQNGGAVIFGGVDNSLYTGQIFWAPVTQELYWQIGVEEFLIGGQATGWCQQGCQAIVDTGTSLLTVPQQFMSALQQATGAQQDQYGQLAVNCNSIQSLPTLTFIINGVQFPLPPSAYVLNTNGYCFLGVEPTYLPSQNGQPLWILGDVFLRSYYSVYDMGNNRVGFATAA
What is the function of this protein?
Hydrolyzes a variety of proteins.
What are the official names of this protein?
Gastricsin, Pepsinogen C-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RIT2_HUMAN
Sequence: MEVENEASCSPGSASGGSREYKVVMLGAGGVGKSAMTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQAEFTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQVRHTYEIPLVLVGNKIDLEQFRQVSTEEGLSLAQEYNCGFFETSAALRFCIDDAFHGLVREIRKKESMPSLMEKKLKRKDSLWKKLKGSLKKKRENMT
What is the function of this protein?
Binds and exchanges GTP and GDP.  Binds and modulates the activation of POU4F1 as gene expression regulator.
What are the official names of this protein?
GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Nucleus. Cell membrane. Note=Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).
Protein: ARGB_CUPNH
Sequence: MNADNPGPAATTVAAIAPALKAEILAEALPYIRKFHGKTIVVKYGGNAMTEEKLKHGFARDVILLKLVGMNPVVVHGGGPQIDEALKKVGKVGTFVQGMRVTDEETMEVVEWVLGGEVQQDIVMLINQYGGQAVGLTGKDGGLIRAKRLQMPDRENPGAFIDIGYVGDIEAINPAVVKALQDDAFIPVISPIGFSDDGQAYNINADVVAGKMAEILKAEKLVMMTNIPGVMDKKGNLLTDLSAREIEELFADGTISGGMLPKISSALDAAKSGVHSVHIIDGRIEHSLLLEILTEQAFGTMIRSH
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALIA_STRPN
Sequence: MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDPDNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDAKWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVGIKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGPYLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARLYPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALLNKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVTYGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQRVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFADPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDETTDVAKRYDKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQDKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK
What is the function of this protein?
Part of the binding-protein-dependent transport system for oligopeptides; probably an oligopeptide binding protein.
What are the official names of this protein?
Oligopeptide-binding protein AliA, Exported protein 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS21_SYNS3
Sequence: MTQVTVGENEGIESALRRFKRQVSKAGIFADLKRLRHHETPIEKYKRKAQQRRRRR
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ACP_BACC7
Sequence: MADVLERVTKIIVDRLGVEETEVVPAASFKEDLGADSLDVVELVMQLEDEFEMEISDEDAEKIATVGDAVTYIESHL
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAZF_STAAN
Sequence: MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTYLSDDKMKEVDNALMISLGLNAVAHQKN
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system, cannot be expressed in E. coli in the absence of cognate antitoxin MazE (PubMed:24748664).  Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis; it cuts between the first and nucleotides of 5'-UACAU-3' in single-stranded RNA (By similarity).  Its endoribnuclease activity is neutralized by coexpression with cognate antitoxin MazE (PubMed:24748664).
What are the official names of this protein?
Endoribonuclease MazF, SaMazF, Toxin MazF, mRNA interferase MazF.
What is the protein family that this protein belongs to?
Belongs to the PemK/MazF family.
Protein: FOLD_STAHJ
Sequence: MVAKILDGKQISKDYRQGLQEQVEALKEKGYTPKLSVILVGNDGASQSYVNSKKKAAEKIGMISEIVHLDEDTSEEDVLKELDRLNNDDSVSGILVQVPLPKQVSEQKILEAINPEKDVDGFHPSNIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKNAVVIGRSHIVGQPVSKLLLQANATVTILHSRTKDMHSHLKDADVIVSAVGQPGLVTKDDVKEGAVIVDVGNTPDENGKLKGDVEFEEVKEVAGAITPVPGGVGPLTITMVLNNTLLAEKMRRGIE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ACDH1_COMTE
Sequence: MTQKKIKCALIGPGNIGTDLLMKLQRSPILEPVWMVGIDPESDGLKRAREMGIKTTADGVDGLLPFVKEDGIQIAFDATSAYVHAENSRKLNELGVLMIDLTPAAIGPYCVPSVNLAEKVAEKAMNVNMVTCGGQATIPMVAAVSRVQAVSYGEIVATVSSRSVGPGTRKNIDEFTRTTSGAVEKIGGAQKGKAIIVINPAEPPLIMRDTIHCLTVDTPKPAEIEASVHAMIKEVQKYVPGYKLVNGPVIDGNRVSIYMEVEGLGDYLPKYAGNLDIMTAAAARTAEMFAEEILAGRFELAEAAVAV
What are the official names of this protein?
Acetaldehyde dehydrogenase 1, Acetaldehyde dehydrogenase [acetylating] 1.
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: ATPD_RHOBA
Sequence: MVKLPSLKFLRRSTDETPNVSETASHSTVLDVGAEKLGKTYARALLAATQADGSTDAVVSDLNAICDEALLHNPKLQLAFQSPQIDADEKCRVVDRLFGGNSHPTLIKLMKVMAKRGRLGYLVAVRDAAVDLFDEAAGRVVAEVRTAVPMTEQLRGEVTQQLSSRFGKTVRLRESVDTELIGGMVIRVGDTVFDSSVASRLDKLGKSAAAGFARQLIEQSDRFSSSS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KAT2B_MOUSE
Sequence: MAEAGGAGSPALPPAPPHGSPRTLATAAGSSASCGPATAVAAAGTAEGPGGGGSARIAVKKAQLRSAPRAKKLEKLGVYSACKAEESCKCNGWKNPNPSPTPPRGDLQQIIVSLTESCRSCSHALAAHVSHLENVSEEEMDRLLGIVLDVEYLFTCVHKEEDADTKQVYFYLFKLLRKSILQRGKPVVEGSLEKKPPFEKPSIEQGVNNFVQYKFSHLPSKERQTTIELAKMFLNRINYWHLEAPSQRRLRSPNDDISGYKENYTRWLCYCNVPQFCDSLPRYETTKVFGRTLLRSVFTIMRRQLLEQARQEKDKLPLEKRTLILTHFPKFLSMLEEEVYSQNSPIWDQDFLSASSRTSPLGIQTVISPPVTGTALFSSNSTSHEQINGGRTSPGCRGSSGLEANPGEKRKMNNSHAPEEAKRSRVMGDIPVELINEVMSTITDPAGMLGPETNFLSAHSARDEAARLEERRGVIEFHVVGNSLNQKPNKKILMWLVGLQNVFSHQLPRMPKEYITRLVFDPKHKTLALIKDGRVIGGICFRMFPSQGFTEIVFCAVTSNEQVKGYGTHLMNHLKEYHIKHEILNFLTYADEYAIGYFKKQGFSKEIKIPKTKYVGYIKDYEGATLMGCELNPQIPYTEFSVIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKDGVRQIPIESIPGIRETGWKPSGKEKSKEPKDPEQLYSTLKNILQQVKNHPNAWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLRNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCASILEKFFFSKIKEAGLIDK
What is the function of this protein?
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation.  Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles.  Also acetylates non-histone proteins, such as ACLY, MAPRE1/EB1, PLK4, RRP9/U3-55K and TBX5.  Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-BMAL1 and CLOCK-BMAL1 heterodimers.  Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5.  Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4.  Acetylates RRP9/U3-55K, a core subunit of the U3 snoRNP complex, impairing pre-rRNA processing.  Acetylates MAPRE1/EB1, promoting dynamic kinetochore-microtubule interactions in early mitosis.  Also acetylates spermidine.
What are the official names of this protein?
Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Histone acetylase PCAF, Lysine acetyltransferase 2B, P300/CBP-associated factor, P/CAF, Spermidine acetyltransferase KAT2B.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. GCN5 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Mainly localizes to the nucleus. Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation.
Protein: REX_LISMC
Sequence: MMEETTKIPQATAKRLPLYHRYLKYLDESGKERVSSAELSEAVKVDSATIRRDFSYFGALGKKGYGYNVSYILDFFSKTLSQDKQTNVALIGVGNLGTALLHYNFMKNNNIKIVAAFDVDPAKVGSVQQDIPIYHLNDMEEIVRENGVEVVILTVPADEAQVTVDRLIEADVKGILNFTPARISVPKQVRVHHIDLTTELQTLIYFLENYPAKTE
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_ACIC5
Sequence: MLDLAFVRANLELVEARLRARGQNPAELLGDFAAVDQHRRERITEAEQLKATRNKLSEEVARLRKAKEDASAVMEETRQLKTKIEDLERAATEAEEQLRERMARIPNLPYEDVPTGASAEDNVEVKRWGTPREFDFAPKPHWELGEQLGILDFERAAKLSGARFAVYWAEGARLERALAAFMLDLHTREHGYTEVLPPLMVNSRSLFGTGQLPKFAEDLFRCEDGEPYQAGKYRENDHWLIPTAEVPLTNLFRDETLDDSQLSTSLVAHTSCFRSEAGSYGKDVRGIIRQHQFQKVELVKFTRPEDSAAEHEALTRHAETVLERLGLPYRRMLLCTGDMGFSSAKTYDLEVWLPGQQVYREISSCSNFDAFQARRAGIRYRPRGQGKSAHVHTLNGSGLAIGRTWLAILENYQQADGSVRIPEALIPYMGTEVIESRNVAQGAK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RER1_YEAST
Sequence: MDYDSSDTMNGGSSNPLITKMNTMKLLYQHYLDKVTPHAKERWAVLGGLLCLFMVRITMAEGWYVICYGLGLFLLNQFLAFLTPKFDMSLQQDEENNELEAGEKSEEFRPFIRRLPEFKFWYNSIRATVISLLLSLFSIFDIPVFWPILLMYFILLFFLTMRRQIQHMIKYRYIPLDIGKKKYSHSSN
What is the function of this protein?
Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.  Required for correct localization of SEC12, SEC71 and SEC63 in the endoplasmic reticulum.
What are the official names of this protein?
Protein RER1, Retention of ER proteins 1.
What is the protein family that this protein belongs to?
Belongs to the RER1 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: PTH_CLOPS
Sequence: MILIVGLGNPGKQYEKTRHNIGFDVIDYMANKYNIDVNREKFKGICGEGFIENKKVILLKPLTYMNLSGESIREFVNFYKLEDDEIIVVYDDISLDIGRLRIREKGSAGGHNGIKSIIQNLGGDKFPRVKVGVGQPKDNLVNHVLGKFSKEDREHIEKVIPVVSDAIVEIVKNDAKESMNKFNGVNIE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_PARXL
Sequence: MDIKRTVLWVIFFMSAVMLFDNWQRDHGRPSMFFPSATPTRTVGSAAPGTTTPGTQPADLPATNAAAPGNAPAATQSQLIKFNTDVYSGEIDTRGGTLSKLSLVKQGDGKQPDLVITLFDRTANHTYLARTGLLGGDFPNHNDIYTPLPNQPHDLTGDEKSFQISFESPVKGGVKVIKTYTFTRGSYVIGVDTKIQNVGTTPVSPSVYMELVRDDQPVETPRFSHTFIGPAVYTDQHHFQKMTFGDIDKNKQDYATSADNGWIAMVQHYFASAWIPQQGAKRDIYVEKIDPALYRVGVKEPVPTIAPGQTVDVSARLFAGPEEERMLEGIAPGLELVKDYGWVTIIAKPLFWLLEKIHSYVGNWGWSIVLLTLLIKAVFFPLSAASYKSMARMKAITPRMQALRERFKGDPQKMNSALMELYKTEKVNPFGGCLPVVIQIPVFISLYWVLLSSVEMRGAPWILWIHDLSQQDPFFILPVLMAVSMFLQTKLNPTPPDPVQAKMMMFMPIAFSVMFFFFPAGLVLYYVVNNVLSIAQQYYITRMMGQAKTKAA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MGSA_CUPMC
Sequence: MRSKPRIALIAHDRKKDDIVAFAGRHRDFLAQCDLLATGTTGGRIAAETGLPVARMLSGPWGGDLQIGAQLAEGRVTAVVFLRDPMTPQPHEPDINALVRACDVHNVPCATNLATAELVVVELARICFEEDQAAADDAAP
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: FMT_SALPC
Sequence: MSDSLRIIFAGTPDFAARHLDALLTSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQHLVADLHADVMVVVAYGLILPKAVLDMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLACPITAEDTSGSLYNKLAELGPQGLITTLKQLADGTATPEAQNEALVTHAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWLEIDGQPVKVWQASVIEDATQSLPGTILAATKQGIQVATGKGILNLLSLQPAGKKAMSAQDLLNSRREWFIPGNRLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: SAV_STRAV
Sequence: MRKIVVAAIAVSLTTVSITASASADPSKDSKAQVSAAEAGITGTWYNQLGSTFIVTAGADGALTGTYESAVGNAESRYVLTGRYDSAPATDGSGTALGWTVAWKNNYRNAHSATTWSGQYVGGAEARINTQWLLTSGTTEANAWKSTLVGHDTFTKVKPSAASIDAAKKAGVNNGNPLDAVQQ
What is the function of this protein?
The biological function of streptavidin is not known.  Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
What are the official names of this protein?
Streptavidin.
What is the protein family that this protein belongs to?
Belongs to the avidin/streptavidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADC_YEAST
Sequence: MPVYEHLLPVNGAWRQDVTNWLSEDVPSFDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQCELQVEWLFKEGSFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATASHKIISLARSTGYKGTIAGTRKTTPGLRRLEKYSMLVGGCDTHRYDLSSMVMLKDNHIWATGSITNAVKNARAVCGFAVKIEVECLSEDEATEAIEAGADVIMLDNFKGDGLKMCAQSLKNKWNGKKHFLLECSGGLNLDNLEEYLCDDIDIYSTSSIHQGTPVIDFSLKLAH
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.