PharMolix/UniProtQA huggingface dataset:
Protein: KEFB_SALA4
Sequence: MEGADLLTAGVLFLFAAVAAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVDEILHFSELGVVFLMFIIGLELNPSRLWQLRRSIFGVGAAQVLLSAAVLAGLLMLADFLWQAAVVGGIGLAMSSTAMALQLMREKGMNRSESGQLGFSVLLFQDLAVIPALALVPLLAGSADEHFDWFKVAMKVLAFAVMLIGGRYLLRPVFRFIAASGVREVFTAATLLLVLSAALFMDALGLSMALGTFIAGVLLAESEYRHELENAIDPFKGLLLGLFFISVGMSLNLGVLYTHLLWVAASVVILVVIKMLTLYLLARLYGIRSSERMQFASVLSQGGEFAFVLFSTASSQRLFQGDQMALLLVTVTLSMMTTPLLMKGIDKWLSRRLNGPEENDEKPWVEDDKPQVIVVGFGRFGQVIARLLMANKMRITVLERDIGAVNLMRKYGYKVYYGDATQVELLRSAGAEAAESIVITCNEPEDTMKLVALCQQHFPHLHILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLVSLGMHPHQAQRAQLHFRRLDMRMLRELIPEHSDMVQISRAREARRELEEIFQREMQQERRQLDGWDEFE
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CH10_TATMI
Sequence: MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPTRGEIIAVGPGKVLENGDVRALAVKVGDVVLFGKYSGTEVKISGQELVVMREDDIMGVIEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_ALCBS
Sequence: MTQEKHNAAILGGGSFGTAMASILAANGHNVNLWVRDPETAAAINIDRENTRYLPGAELPKEVTATDSLEEALGGASMVFVAIPSKAFAEVLEQARQWVPDEAVVISCTKGIYADGFLLMSELLHQYWPHTRIGVLSGPNLAKEVVEQKFTGTVIASPDETLRQTVQNALSCDYFRVYDNPDIYGVELGGALKNIYAVASGMAAAIGVGENSRSFLITRALAEMSRFAVKLGANPMTFLGLSGVGDLIATCTSSLSRNYQVGFQLGEGKTLEQAIECLGQTAEGINTIKLVADKAAELDVYMPLATALYKIVYHGQPLELMIQNLMSGEYKHDVEFQLGAFTS
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KC2D1_DANRE
Sequence: MASTTCTRFTDEYQLYEELGKGAFSVVRRCMKISTGQEYAAKIINTKKLSARDHQKLEREARICRLLKHANIVRLHDSISEEGVHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVQGDQQAWFGFAGTPGYLSPEVLRKEPYGKPVDMWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPAKRITAAEALKHPWICQRSTVASMMHRQETVECLKKFNARRKLKGAILTTMLATRNFSSKNPYKKPDGVKEPQTTVIHNPTDGNKESSESTNTTIEDEDIKARKQEIIKVTELLIEAINNGEFEAYTKICDPGLTSFEPEALGNLVEGTDFHRFYFENSLSKGHKPIHTILLNPHVHLIGEDAACIAYIRLTQYMDVNNMPRTMQSEETRVWHRRDGKWQNIHFHRSGSPTVPTK
What is the function of this protein?
CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system.
What are the official names of this protein?
Calcium/calmodulin-dependent protein kinase type II delta 1 chain, Calcium/calmodulin-dependent protein kinase type II delta-B chain, CaM kinase II subunit delta-B, CaM-kinase II delta-B chain, CaMK-II subunit delta-B.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: ASSY_RHOE4
Sequence: MADRVVLAYSGGLDTSVAISWIGKETGAEVVAVAIDLGQGGEDMEVVRQRAIDCGAVESVVVDARDEFADEYCLPTIAANALYMDRYPLVSAISRPLIVKHIVEAARSHGGTIVSHGCTGKGNDQVRFEVGFGALAPDLQVIAPVRDYAWTREKAIAFAEENNIPINVSKKSPFSIDQNVWGRAVETGFLEDLWNAPTKDVYDYTQDPTVNWNAPDELIISFDKGRPVAIDGRPVSVLEAIQELNKRAGAQGVGRLDVVEDRLVGIKSREIYEAPGAMVLITAHQELEHVTLERELGRYKRQMEQRWSELVYDGLWFSPLKDALDTFVNKTQERVTGDIRLFLHGGAITVNGRRSPESLYDFNLATYDEGDSFDQSASKGFVEIHGLSSKVAAKRDLGL
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSAB_MYCTO
Sequence: MSAQIDPRTFRSVLGQFCTGITVITTVHDDVPVGFACQSFAALSLEPPLVLFCPTKVSRSWQAIEASGRFCVNVLTEKQKDVSARFGSKEPDKFAGIDWRPSELGSPIIEGSLAYIDCTVASVHDGGDHFVVFGAVESLSEVPAVKPRPLLFYRGDYTGIEPEKTTPAHWRDDLEAFLITTTQDTWL
What is the function of this protein?
Catalyzes the reduction of free flavins (FMN or FAD) by NADH.  Subsequently, the reduced flavins diffuse to the HsaA oxygenase subunit (By similarity).
What are the official names of this protein?
Flavin-dependent monooxygenase, reductase subunit HsaB, 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4-hydroxylase, reductase subunit, Flavin:NADH reductase.
What is the protein family that this protein belongs to?
Belongs to the non-flavoprotein flavin reductase family.
Protein: RERGL_DANRE
Sequence: MNDIKVAVLGSEGVGKSALIVRFLTRRFIGEYASSSECIYRKRMSIDARQLNLELHDPCSQPCDGKSTLNEQIHWADGFVVVYDISDRSSFLTAKAIVHLIRELHLGATKRDSDSVIFLVGNKQDLCHMREVDREEGQKLASESRCQFYELSAAEHYQEVLLMFSKIVRNASLGSKAKERRRRPSGSKSMAKLINNVFGKRRKSV
What is the function of this protein?
Binds GDP/GTP and may possess intrinsic GTPase activity.
What are the official names of this protein?
Ras-related and estrogen-regulated growth inhibitor-like protein, RERG/Ras-like protein.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
Protein: YGEK_ECO57
Sequence: MGKIKIVVSDQQPFMIDGIIGFLGHYPDLYEVVGGYKDLKKAIAECNKSAAQIFILGEFAGGMMGAELVKWVKSHKIDAHIITFVAKMPYIDSIKLLEAGAKGCVWKTSHPAKLNRAIDSISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESEILQLIADGKTNKEIANFLQLSRKTVETHRLNIMKKLDVHSGIELIKTALRMGVCTI
What are the official names of this protein?
Uncharacterized response regulatory protein YgeK.
Protein: PCKA_BRADU
Sequence: MQETGVRNGAFGADKFGLKNLKQVHWNLGAPQLYQYSLSAGEAVLSADGALCADTGEFTGRSPKDKFTVRDATTDKKMWWAGNQSITAEQFETLYQDFLKHAEGKSLFAQDLYGGADPAYRIKTRVFTELAWHSLFIRTLLIRPEAIELSTFTPELTIIDMPSFRADPKRHGCKSENVVAIDFARKIVLIGGSYYAGEMKKSVFTTLNYYLPERGVMPMHCSANVGAKDDAAIFFGLSGTGKTTLSADPNRTLIGDDEHGWGPNGVFNFEGGCYAKCIKLSQEAEPQIYAASTRFGAVLENCVLDEDTRVVDFDDGSKTENTRSAYPLDFIPNASRTGRAPQPKNVVMLAADAFGVLPPIAKLSPAQAMYHFLSGYTAKVAGTERGLGNEPQPEFSTCFGSPFLPLDPSVYGNMLRDLIAQHNVDCWLVNTGWTGGKYGTGSRMPIKVTRALLTAALDGSLRNVEFRTDKYFGFAVPTALPGVPSEILNPVNTWKDKDEFDKTARALVGMFQKNFAKFEAQVDAEVRAAAPDVKLAAE
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSTT_STRPB
Sequence: MKKIYDLWVRVSLIKKIGIGVVIGVMLGILAPDLTGFSILGKLFVGGLKAIAPLLVFALVSQAISHQKKGKQTNMTLIIVLYLFGTFASALVAVLTAYLFPLTLVLNTPVNTELSPPQGVAEVFQSLLLKLVDNPINALATANYIGVLSWAIIFGLALKAASQETKHLIKTAAEVTSQIVVWIINLAPIGIMSLVFTTISENGVGILSDYAFLILVLVGTMVFVALVVNPLIAVLITRQNPYPLVLRCLRESGLTAFFTRSSAANIPVNMQLCQKIGLSKDTYSVSIPLGATINMGGAAITINVLTLAAVHTFGIPIDFLTALLLSVVAAVSACGASGVAGGSLLLIPVACSLFGISNDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTAIAENAFWKRKKA
What is the function of this protein?
Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
What are the official names of this protein?
Serine/threonine transporter SstT, Na(+)/serine-threonine symporter.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYT_CRYNI
Sequence: MVHSQLPVAASLRLLCALLLLPSATMIPGGLSPRSVTDPDVREAAEFAVQEYNALSANAYYYKQLRIVEAQSQVVAGAKYYLTMELMKTKCAKTTGKPKVYKEIQNCELPPKAQQEKLTCRFQVWSRPWLKKTELTKMSCN
What is the function of this protein?
Inhibits various C1 cysteine proteases including cathepsin L, papain and cathepsin B.  This protein has no toxic activity and its function in the venom is unknown.  It may play a role as a housekeeping or regulatory protein (By similarity).
What are the official names of this protein?
Cystatin.
What is the protein family that this protein belongs to?
Belongs to the cystatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RF3_STRR6
Sequence: MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILGIASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDDIELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNVTQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVELEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MANA_ASPOR
Sequence: MKLNPSLLTAAGLVSAQLASALPQASSSTVSPSPSPSATPGSFVTTSGLNFVIDGKTGYFAGSNSYWIGFQKNNDDVDLVFSHLQESGLKILRVWGFNDVNQKPTDGSVYYHLLADGTATVNEGEDGLQRLDYVVSSAEKHGIKLIINFVNFWDDYGGINAYVKAFGGSKEGFYTNDAMQAAYRAYIKAVISRYSDSTAIFAWELANEPRCQGCETTVLYNWIESTSQYIKSLDSKHLVCIGDEGFGLDTGSDGSYPYQYSEGSDFAKNLAIPTIDFGTFHLYPSSWGTTNDWGNGWVTSHGAACKAAGKPCLFEEYGVTSDHCAVEKPWQNTALNTTAISGDLYWQYGDQLSGGPSPDDGNTFYYGTDDFKCLVTDHIAAINSRK
What is the function of this protein?
Endo-1,4-mannanase, a crucial enzyme for depolymerization of seed galactomannans and wood galactoglucomannans.
What are the official names of this protein?
Probable mannan endo-1,4-beta-mannosidase A, Endo-beta-1,4-mannanase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: PSBY_PORPU
Sequence: MDSRLLIVLIPVLAAASWAVYNIGRVALQQFRKMTS
What is the function of this protein?
Manganese-binding polypeptide with L-arginine metabolizing enzyme activity.  Component of the core of photosystem II.
What are the official names of this protein?
Photosystem II protein Y.
What is the protein family that this protein belongs to?
Belongs to the PsbY family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: SYI_HAES1
Sequence: MTDYKNTLNLPETGFPMRGDLAKREPDMLKNWYDKNLYQKVREASKGKKTFILHDGPPYANGTLHLGHAVNKILKDIIMKSKTALGFDTPYVPGWDCHGLPIELKVEGLVGKPNEKISAAEFRQACRDYAKEQVEGQKADFIRMGVLGDWDNPYLTMNFETEAEIIRTLGKVIQNGHLYKGSKPVHWCLDCASSLAEAEVEYEDKVSPSIYVRFAAVSAAEVEEKFNALGKGQGALSAVIWTTTPWTLPSNRAIAVNAELEYQLVQLGNERVILATELVQTVQNALGIEQIQILGSAKGGDLELIRFNHPFYDFSVPMILGDHVTVDGGTGLVHTAPDHGQDDFVVSKKYGLEMAGLVANDGKFISSTPFFAGKGVFEANDLVLEKLKETGALLKLERIKHSYPHCWRHKTPIIFRATPQWFIGMETQDLRIKALSEIKSVRWIPSWGEARIDKMVANRPDWCISRQRTWGVPMTMFVHNETEELHPRTLELLEDIAKRVEKAGIQAWWDLDPAELLGEEAKTYHKVPDTLDVWFDSGSTYASVVEQRPEFNGKSTDMYLEGSDQHRGWFMSSLMLSTATNNKAPYKQVLTHGFTVDEKGRKMSKSLGNVIVPSEVWNKNGADILRLWVASTDYTGEIAVSHKILNSAGDTYRRIRNTARFLLANLNGFDPKNDLVNPEEMISLDRWAVSCALEAQNEIKEAYDNYQFHTVVQRLMRFCSIEMGSFYLDIIKDRQYTTKADSLARRSCQTALWHISEALVRWIAPILSFTADEIWGYLPKLDNRAEFVFTEEFYDGLFGLDESDKLDDTYWQQLLKVRAEVNRVLEQARNDKLIGAGLEAKVTVYASEEIRPLLEQLGNELRFVLITSQVVVKPLSKADVAESELTGLAVKVERADGEKCPRCWHFATDIGSNKEHSHICGRCIENVEGNGEQRQFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBT_JANMA
Sequence: MITIVSTENDALSAQLAAAINNKTKPLGSLGMLETLARQIGLIQQTTQAQIIDPALIVFAADHGIVAENVSAYPQSVTWQMVENFLAGGAAINVFARQNHCALHIVDAGVNHDFGRREGLLDRKVAYGTRNFAQETAMSAEQCAQAVQAGMDLAAGIKGNVLGFGEMGIGNTTAAAAIMQAMTKLPAAECVGAGTGLAHEGILHKQKVVQDAVAYHAAIVAKNAPLDILATFGGFEIAMIVGAMLKAAERRMVLLIDGFIITSALMIAARLQPSILDYCVFAHCSDEHGHRQMISHLGGRPVLQMGLRLGEGTGSVLALPLLHAAVNFLREMATFESADVSQQNA
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: MLTC_SHIDS
Sequence: MKKYLALALIAPLLISCSTTQKGDTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLKNRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase C, Murein lyase C.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: SIAL_MOUSE
Sequence: MKTALILLSILGMACAFSMKNFHRRIKAEDSEENGVFKYRPRYFLYKHAYFYPPLKRFPVQGGSDSSEENGDGDSSEEEGEEEETSNEEENNEDSEGNEDQEAEAENSTLSTLSGVTASYGAETTPQAQTFELAALQLPKKAGDAESRAPKVKESDEEEEEEEEEEENENEEAEVDENELAVNGTSTNSTEVDGGNGSSGGDNGEEAEAEEASVTEAGAEGTTGGRELTSVGTQTAVLLNGFQQTTPPPEAYGTTSPPIRKSSTVEYGGEYEQTGNEYNNEYEVYDNENGEPRGDTYRAYEDEYSYYKGHGYEGYEGQNYYYHQ
What is the function of this protein?
Binds tightly to hydroxyapatite.  Appears to form an integral part of the mineralized matrix.  Probably important to cell-matrix interaction.  Promotes Arg-Gly-Asp-dependent cell attachment (By similarity).
What are the official names of this protein?
Bone sialoprotein 2, Bone sialoprotein II, BSP II, Cell-binding sialoprotein, Integrin-binding sialoprotein.
What are the subcellular locations of this protein?
Secreted.
Protein: RIBB_ECO55
Sequence: MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDLMTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: CH60_FRATO
Sequence: MAAKQVLFSDEARAKMLDGVNTLANAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAKEIELEDKFENMGAQIVKEVASKTADVAGDGTTTATVLAQALLTEGLKAVTAGMNPMDLKRGIDKATARLVEELKALSKPCSDPKSIEQVGTISANSDATVGKLIADAMAKVGKEGVITVEEGKGFEDELDVVEGMQFDRGYLSPYFATNQENMTTDLENPYILIVDKKISNIRDLLPILEGVSKSGRALLIIAEDVESEALATLVVNNMRGVVKVCAVKAPGFGDRRKAMLEDIATLTGATFVSEDLSMKLEETNMEHLGTASRVQVTKDNTTIIDGAGEKEAIAKRINVIKANIAEANSDYDREKLQERLAKLSGGVAVIKVGAVTEAEMKEKKDRVDDALHATRAAVEEGIVAGGGVALIRAQKALDGLTGENDDQNHGIALLRKAIEAPLRQIVSNAGGESSVVVNQVKANQGNYGYNAANDTYGDMVEMGILDPTKVTRSALQHAASIAGLMITTEAMIGEIKEAAPAMPMGGGMGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_RUMCH
Sequence: MFAYIKGTVEEKNNDSIIVEAGGIGYRIFTALSTINNMGQNGTTVKIYTHYYVREDIAVLYGFGTVEELTMFEMLLTVSGVGPKAAISMISTLSPSRFYLAVVSQDTKSLTKAPGIGMKMAQRIILDLKDKISKEQLTSSIPMTSPENNEVTGDSVLSEAVSALMVLGYGSAEASSTISGIYEKGISVEELVKKALKSL
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LAC3_TRAVI
Sequence: MSFSSLRRALVFLGACSSALASIGPVTELDIVNKVIAPDGVARDTVLAGGTFPGPLITGKKGDNFRINVVDKLVNQTMLTSTTIHWHGMFQHTTNWADGPAFVTQCPITTGDDFLYNFRVPDQTGTYWYHSHLALQYCDGLRGPLVIYDPHDPQAYLYDVDDESTVITLADWYHTPAPLLPPAATLINGLGRWPGNPTADLAVIEVQHGKRYRFRLVSTSCDPNYNFTIDGHTMTIIEADGQNTQPHQVDGLQIFAAQRYSFVLNANQAVNNYWIRANPNRANTTGFANGINSAILRYKGAPIKEPTTNQTTIRNFLWETDLHPLTDPRAPGLPFKGGVDHALNLNLTFNGSEFFINDAPFVPPTVPVLLQILNGTLDANDLLPPGSVYNLPPDSTIELSIPGGVTGGPHPFHLHGTDNPGPWFLHCHIDFHLQAGLAIVFAEDAQDTKLVNPVPEDWNKLCPTFDKAMNITV
What is the function of this protein?
Lignin degradation and detoxification of lignin-derived products.
What are the official names of this protein?
Laccase-3, Benzenediol:oxygen oxidoreductase 3, Diphenol oxidase 3, Urishiol oxidase 3.
What is the protein family that this protein belongs to?
Belongs to the multicopper oxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: YBOX1_CHICK
Sequence: MSSEAETQPPAAPVPAAPAAAPADSKPNGGSGNGSSGLASAAPPAGGDKKVIATKVLGTVKWFNVRNGYGFINRNDTKEDVFVHQTAIKKNNPRKYLRSVGDGETVEFDVVEGEKGAEAANVTGPGGVPVQGSKYAADRNHYRRYPRRRGPPRNYQQNYQNSESGEKNEGAENIPEGQAQQRRPYRRRRYPPYYMRRPYGRRPQYSNPPVQGEIVEGADNQGAGEQGRPVRQNMYRGYRPRFRRGPPRQRQPREDGNEEDKENQGDETQGQQPPQRRYRRNFNYRRRRPENPKPQDGKETKTAEPPAENTSAPEAEQGGAE
What is the function of this protein?
DNA- and RNA-binding protein involved in various processes, such as translational repression, RNA stabilization, mRNA splicing and transcription regulation (PubMed:8321222).  Binds preferentially to the 5'-[CU]CUGCG-3' RNA motif and specifically recognizes mRNA transcripts modified by C5-methylcytosine (m5C) (By similarity).  Promotes mRNA stabilization: acts by binding to m5C-containing mRNAs and preventing mRNA decay (By similarity).  Plays a role in the maternal-to-zygotic transition in early embryo by binding to m5C-containing maternal mRNAs and preventing their degradation (By similarity).  Also promotes maternal-to-zygotic transition in oocytes and embryos by promoting translation repression; molecular mechanisms governing translation repression are unknown (By similarity).  Plays a key role in RNA composition of extracellular exosomes by defining the sorting of small non-coding RNAs, such as tRNAs, Y RNAs, Vault RNAs and miRNAs (By similarity).  Probably sorts RNAs in exosomes by recognizing and binding C5-methylcytosine (m5C)-containing RNAs (By similarity).  Acts as a key effector of epidermal progenitors by preventing epidermal progenitor senescence: acts by regulating the translation of a senescence-associated subset of cytokine mRNAs, possibly by binding to m5C-containing mRNAs (By similarity).  Also involved in pre-mRNA alternative splicing regulation: binds to splice sites in pre-mRNA and regulates splice site selection (By similarity).  Also able to bind DNA and regulate transcription (PubMed:8321222).  Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3') (By similarity).  Promotes separation of DNA strands that contain mismatches or are modified by cisplatin (By similarity).  Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA, suggesting a role in DNA repair (By similarity).  The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation (By similarity).
What are the official names of this protein?
Y-box-binding protein 1, YB-1, Y-box transcription factor.
What is the protein family that this protein belongs to?
Belongs to the YBX1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasmic granule. Secreted. Secreted, extracellular exosome.
Protein: PEPT_CLOB6
Sequence: MKDVLERFLGYIRIDTQSSEESDTVPTTKTQLEFAKKLGEELKAIGLKDVSVDENGYVMATLESNIDKKVPTIGFIAHMDTSPDLSGTNINPRIVEKYDGQDIVLNKEKNIVLKINEFPEILEYKGQDIVVTDGNTLLGADDKAGIAEIITAMEYLINHPEIKHGTIKVGFTPDEEVGKGADHFDVKKFGADLAYTLDGGGIGELECETFNAAKAKVIIEGRNVHPGSAKNKMTNAVLVANKFINMLPENEVPERTEGYEGFFHLLSVKSEVETAELNYIIRDFDRKKFEERKEQIKEVGKKINEEYNKEIVCVKVEDQYYNMKEKIDEVKYVVDIAHDAMKAIDIEPILVPIRGGTDGSRLSFMGLPTPNLFAGGHNFHGRFEFVPVLSMEKAAELVVKIAELYANR
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPB_YERE8
Sequence: MKFDVIIIGGGLAGLVCGIRLAEQGKYCAIVSAGQNALHFSSGSLDLLAKLPNGQAVSQPLSALETLAELAPEHPYSKMGQTGQVGELAQQAESLLSRCGLSLVGSAAKNHLRLTPLGNCRPTWLSPADIPVAPLEGPLPWQKVAVIGIEGFLDFQPQMVASALQEQGVEVTSDYLHLPALDRLRDNPSEFRAVNIARVLDLPENLQPLADELARLSSTAEMILLPACIGLDESAPLEALRAAVGKPIQLLPTLPPSLLGMRLHQALRHRFQQLGGIVMPGDAVLRAELVGNRITGLYSRNHGDIPLRAAQMVLASGSFFSNGLVATFEHVYEPILDLDILSLPNRADWSNSNMFAPQPYLQFGVNTDNRLRALRGGVALDNLHVIGAVLGGYDPLQQGCGAGVSLTSALFVAEQIVSAMEVTL
What is the function of this protein?
Conversion of glycerol 3-phosphate to dihydroxyacetone.  Uses fumarate or nitrate as electron acceptor.
What are the official names of this protein?
Anaerobic glycerol-3-phosphate dehydrogenase subunit B, Anaerobic G-3-P dehydrogenase subunit B, Anaerobic G3Pdhase B.
What is the protein family that this protein belongs to?
Belongs to the anaerobic G-3-P dehydrogenase subunit B family.