PharMolix/UniProtQA huggingface dataset:
Protein: RS21A_AGRFC
Sequence: MQVLVRDNNVDQALRALKKKMQREGIFREMKMRDYYEKPSQKRAREKAEAVRRVRKLARKRAQREGLIAAPRASR
What are the official names of this protein?
30S ribosomal protein S21 A.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: SYS_PARXL
Sequence: MLDIQLLRKDLDGVAKRLADRGYTLDVAAFTALEAERRDTQTRTEEMQARRNSLSKQIGALKGKGEDTSAVMAEVSGIGDEMKASAARLDEIQKRLSDLLLGVPNLPHESVPLGKDETENVEVRRWGTPRQFEFEVKDHVDVGAPLGLDFETGAKLSGARFTMLRGQIARLHRALAQFMIDTHTQHHGYTEIYTPYIVNPEILYGTGQLPKFADDMFRVEKGGDENTVTQYLISTSEISLTNTVRDSILEADALPIKLTAHSPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQIVAPETSYDALEQMVGHAETILQKLELPYRVITLCTGDMGFSAAKTYDLEVWVPAQNTYREISSCSNTESFQARRMQARYRNAQGKPELVHTLNGSGLAVGRTLVAVLENFQNADGSVTVPVALRPYLGGLERLELPAA
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_MYCCT
Sequence: MKVRSSVKQICDKCRVIRRKGRVMIICVTPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DTD_STRA5
Sequence: MKIIIQRVNQASVSIEDDVVGSIEKGLVLLVGIAPEDTTEDIAYAVRKITSMRIFSDDEGKMNLSIQDIKGSVLSISQFTLFADTKKGNRPAFTGAADPVKANQFYDIFNQELANHVSVETGQFGADMQVSLINDGPVTIVLDTKNK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BLA2_KLEPN
Sequence: MRYIRLCIISLLATLPLAVHASPQPLEQIKQSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGASERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
What is the function of this protein?
This enzyme hydrolyzes cefotaxime, ceftazidime and other broad spectrum cephalosporins.
What are the official names of this protein?
Beta-lactamase SHV-2, SHV-2A.
What is the protein family that this protein belongs to?
Belongs to the class-A beta-lactamase family.
Protein: COG6_ARATH
Sequence: MASTVGLAPGLSRKLKKVLDCRTDSPDLVASLNALSSFYDENSAHARRNLRSTIEKRALQINSEFLNAADSTQIALDRVEEEVNALADCCDKIAAALSSSAATTSDIISTTERLKQELEVTTQRQEIVNCFLRDYQLSNEEIKALREDELNENFFQALSHVQEIHSNCKLLLRTHHQRAGLELMDMMAVYQEGAYERLCRWVQAECRKLGDTDNPEVSELLRTAVRCLKERPVLFKYCAEEVGNLRHNALFRRFISALTRGGPGGMPRPIEVHAHDPLRYVGDMLGWLHQALASERELVHALFDIDSADHQSNAKNTSENIALKAGESDFTFVLDRIFEGVCRPFKVRVEQVLQSQPSLIISYKLTNTLEFYSYTISDLLGRDTALCNTIGMVKDAAQKTFFDILKTRGEKLLRYPPPVAVDLSPPPAVREGVSLTLEIIENYNSMMVSASGEKPAFDPVLSALLDPIIKMCEQAAEAHKSKKSGQLPRRSRTSSDSSQLTSVDALLSSSPSPPQNNETPSKIFLINCLCAIQQPLLRHDVASQYVTNIGLMIENHINLLVQNEVDTLLHKCGLSDKMQIFRSSTSELPLSERQDTSPAMLSECLKAFFGLVLGSEGSLPEFEQIQVPKLRSEACVRVAKTLAEAYEVIYQAVTDQQNGYPDPKSLARHPPDQIRTILGI
What is the function of this protein?
Required for normal Golgi function.
What are the official names of this protein?
Conserved oligomeric Golgi complex subunit 6, COG complex subunit 6, Component of oligomeric Golgi complex 6.
What is the protein family that this protein belongs to?
Belongs to the COG6 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein.
Protein: Y2021_HALSA
Sequence: MADAPPTDEGWFVLHDCYTVDWDAWRDAPERDRTAALDDAASFLADREALADADEGESGVFSITGQKADLLFVHFRESLDELDRIQRAFEQTAFAEYTERAHSYVSVVEISGYTAPDYFEDPDSVDDGLRQYFESKLTPEIPDDTYVSFYPMSKRRQPEQNWYDLPIEERAEMMDVHGDLGKQYAGKVSQVIASSVGLDDMEWGVTLFADDLTDIKDIVYEMRFDEVSAKYGAFGDFFVGRRFPPADLPAFMAGERVPAPEGGADAHGEGERTHHHGDSDHHDGDDGEQHHHSTGDEADDGIRGELADEDIYAGQPHGEDVYATVLYSEAGADDLFEEVEGLRGNFEHYDTHVKTAVYDGHEADRRAVVSIWDTASAADTAAGFLADLPEVVERAGEESGFGTMGMFYETKPEHTAEFVEKFDTVAGVLADMDGHFDTDLMVNVENDDDMFIASQWRSQEDAMAFFRSDDFGDTVDWGRDVLADRPRHVFLA
What are the official names of this protein?
Putative heme-binding protein VNG_2021C.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the ChdC family.
Protein: NUSB_STRMK
Sequence: MNKNTQGKPSGKPVRRDGVDPVLRSRARRRAVQAIYAWQISGGNAQSLIAQFAHEQAREIADLAYFEALLHGVLDNRRDIDEALGPYLDRGIEEVDAIERAVLRLAGYELRYRLDVPYRVVINEAIESAKRFGSEHGHTYVNGVLDRAAVEWRKVESGH
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: AGAL2_ARATH
Sequence: MVLLSFSLRFIAFTLTITLTQIADGFQSRMLMNNGLALSPQMGWNSWNHFQCNINETLIKQTADAMVSSGLSAIGYKYINIDDCWGELKRDSQGSLVAKASTFPSGIKALSDYVHSKGLKLGIYSDAGTLTCSQTMPGSLGHEEQDAKTFASWGIDYLKYDNCENTGTSPRERYPKMSKALLNSGRSIFFSLCEWGQEDPATWAGDIGNSWRTTGDIQDNWKSMTLIADQNDRWASYARPGSWNDPDMLEVGNGGMTKEEYMSHFSIWALAKAPLLIGCDLRSMDKVTFELLSNKEVIAVNQDKLGIQGKKVKKEGDLEVWAGPLSKKRVAVILWNRGSASANITARWAEIGLNSSDIVNARDLWEHSTYSCVKKQLSALVEPHACKMYTLTRRKA
What is the function of this protein?
May regulate leaf (and possibly other organ) development by functioning in cell wall loosening and cell wall expansion.
What are the official names of this protein?
Alpha-galactosidase 2, AtAGAL2, Alpha-D-galactoside galactohydrolase 2, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted, cell wall. Secreted, extracellular space, apoplast.
Protein: PARL_BOVIN
Sequence: MAWRGWAQRGWGCGQAWTLPVCGGSYEELTAALAPSRLLRRRFNFFIQQKCGFRKAPRKVEPRRSDTSSEAYKRSALIPPVEETAFYPSPYPIRTLVKPLFFTVGFTGCAFGSAAIWQYESLKSKVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVFVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISTFVSYVCKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYITYGHELIWKNREPLVKIWHEMRTNSPKKGGGSK
What is the function of this protein?
Required for the control of apoptosis during postnatal growth.  Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals (By similarity).  Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP).  Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain (By similarity).
What are the official names of this protein?
Presenilins-associated rhomboid-like protein, mitochondrial, Mitochondrial intramembrane cleaving protease PARL.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [P-beta]: Nucleus. Note=Translocated into the nucleus by an unknown mechanism.
Protein: OAME_ACESD
Sequence: MEKDLQLRVNEKLDVENILKDLDKYTPKRRGWTWRQPAENLQMGPFIYKDASTPLENSVALPSAKYFGDIDPQPLPVITTEIASGRFEDDIRRMRMAAWHGADHIMVIRTAGQSHYDGLIEGTPQGIGGVPITRKQVRAQRKALDLIEEEVGRPINYHSYVSGVAGPDIAVMFAEEGVNGAHQDPQYNVLYRNINMIRSFIDACESKTIMAWADMAQIDGAHNANATAREAWKVMPELMVQHALNSIFSLKVGMKKSNICLSTVPPTAPPAPSMYLDLPYAVALREMFEGYRMRAQMNTKYMEASTREATVTHVLNLLISKLTRADIQSTITPDEGRNVPWHIYNIEACDTAKQALIGMDGLMDMVQLKREGVLGDTVRELKERAVLFMEEIIEAGGYFNAVEQGFFVDSGYYPERNGDGIARQINGGIGAGTVFERDEDYMAPVTAHFGYNNVKQYDEALVSEPSKLIDGCTLEVPEKIVYIDELDENDNVNVRMEETKEFRHSSMIKPEVEWQADGTVLLTMFLPTSKRVAEFAAIEFAKKMNLEEVEVINREVMQEAEGTRIELKGRVPFSIDINSLVIPPEPEILSEDEIREDIEKTPLKIVAATVGEDEHSVGLREVIDIKHGGIEKYGVEVHYLGTSVPVEKLVDAAIELKADAILASTIISHDDIHYKNMKRIHELAVEKGIRDKIMIGCGGTQVTPEVAVKQGVDAGFGRGSKGIHVATFLVKKRREMREGK
What is the function of this protein?
Component of a complex that catalyzes the reversible migration of the omega amino group of D-ornithine to C-4 to form (2R,4S)-2,4-diaminopentanoic acid.  OraE may be the catalytic subunit.  Active only on D-ornithine and 2,4-diaminopentanoic acid but not active on L-ornithine, L-beta-lysine, L-alpha-lysine or D-alpha-lysine.
What are the official names of this protein?
D-ornithine 4,5-aminomutase subunit beta, D-ornithine aminomutase E component, OAM-E.
Protein: PYM_DROME
Sequence: MSTYLQSSEGKFIPATKRPDGTWRKARRVKDGYVPQEEVPLYESKGKQFVAQRQAGVPPGMCPLLAAESKKEREKQERTRAKKQEKESGRQPKAPAPGVLVMPPSTCPPPKVSQQQQQQQQQPSGSRDINSISKTLEDTLKLDAAQEVVDPAKQLKKLRKKIREIEQIESRIQAGEQKKLDKDQLDKVKKKSEILRQIKDLESTPRS
What is the function of this protein?
Regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation.  Acts as an EJC disassembly factor by disrupting mature EJC from spliced mRNAs.  Required for normal localization of osk mRNA to the posterior pole of the developing oocyte.  Does not interact with the small ribosomal unit or components of the translation initiation complex.  May not function in cap-dependent translation regulation.
What are the official names of this protein?
Partner of Y14 and mago, DmPYM, Protein within the bgcn gene intron.
What is the protein family that this protein belongs to?
Belongs to the pym family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm. Nuclear export is mediated by emb/Crm1.
Protein: MTNN_BACAC
Sequence: MRIAVIGAMEEEVRILRDKLEQAETETVAGCEFTKGQLAGHEVILLKSGIGKVNAAMSTTILLERYKPEKVINTGSAGGFHHSLNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADEALVALAEKCMQAEENIQVVKGMIATGDSFMSDPNRVAAIRDKFENLYAVEMEAAAVAQVCHQYEVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLEELK
What is the function of this protein?
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.  Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.
What are the official names of this protein?
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, MTA/SAH nucleosidase, MTAN, 5'-deoxyadenosine nucleosidase, DOA nucleosidase, dAdo nucleosidase, 5'-methylthioadenosine nucleosidase, MTA nucleosidase, S-adenosylhomocysteine nucleosidase, AdoHcy nucleosidase, SAH nucleosidase, SRH nucleosidase.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Protein: HIS4_HERA2
Sequence: MQLIPAIDLRDGRCVRLVQGDFEQTTVYGDDPVAVAQQWEAAGAARIHIVDLDGAKAGRPTQTSTIAAITKAVSVPVQLGGGLRDAASIAAAFELGVSDVILGTVAVRNPELVAELVRQYGKAITIGIDARNGVVATEGWLASSRQRATELAEQMGQLGVARIIYTDISRDGTLSEPNYAQTAALVTPNGPAIIASGGIARVEHLARLAELGISGAIIGTALYTGHIDLASAIQTIEHGG
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_PSEA7
Sequence: MSVEKTNQSWGGRFSEPVDAFVARFTASVDFDKRLYRHDIMGSIAHATMLAKVGVLSDAERDAIVDGLQQIQAEIEAGSFDWRVDLEDVHMNIEARLTDRIGVTGKKLHTGRSRNDQVATDIRLWLRDEIDTILAEITRLQQGLLGLAEAEADTIMPGFTHLQTAQPVTFGHHLLAWFEMLGRDYERLVDCHRRVNRMPLGSAALAGTTYPIQREITCQLLGFEAIGGNSLDGVSDRDFAIEFCAAASLAMMHLSRFSEELVLWTSAQFQFIDLPDRFCTGSSIMPQKKNPDVPELVRGKSGRVFGALTGLLTLMKGQPLAYNKDNQEDKEPLFDAADTLRDSLRAFADMVPAIRPRREVMREAARRGFSTATDLADYLVRKGLPFRDCHEIVGHAVKYGVDSGKDLAEMSLDELRRFSEQIDADVFAVLTLEGSVNARDHIGGTAPNQVRAAVARGRQLLAQR
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_GLUOX
Sequence: MLLVIDAGNTNIVFAVHDGESWLGQWRISTNEARTADEYAAWLLTLFDRVGVNAKAITRAIIGTVVPVALYELRRFCREWLDVVPLVANARLDWGIDVLVDNPNELGADRRLNGLAGRELFGAPLIVVDFGTATTFDVVNSAGQFCGGAIAPGVNLSIDALHRAAARLPRMSIGRPTAAIGRNTSVAMRSGLFWGYVGLVEGLIHRISDEMDAKPTVIATGGLAPLFSEGTPLFDVLAPDLTLDGLRLLADRNTGPPLSYSPERSQGIGQ
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPFB_ECO57
Sequence: MDRMMKSKFVALALSLFLSQSVLAGGVGLSSTRVIYDGSKKEASLTVQNKSKTEEFLIQSWVDDAAGSKKTPFIITPPLFKLDPEKNNILRIVNITPGLPQDRESVYWVNVKAIPSKSDDSENKNVLQIAVRTRIKLFYRPAGLKGDVKTAPNELRFTRNGNQLRVDNPTVFNITFNQFFANDKEIEKAGMVPAKGALNITLPAGVGSVSKIKYNTINDFGSXAEMITKNVD
What is the function of this protein?
Part of the lpfABCC'DE fimbrial operon.  LP fimbriae may participate in the interaction with eukaryotic cells by assisting in microcolony formation.
What are the official names of this protein?
Probable fimbrial chaperone LpfB.
What is the protein family that this protein belongs to?
Belongs to the periplasmic pilus chaperone family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LYSX_MYCA1
Sequence: MRRAGRSRQFSSVEEAFSTSAARPGRRGRRSGRENTAKFVPATLSASTSFSRIEGISSRSVTLASPGSRSGSGPRSGPRLGPANRSTSRYRWVPAAAGWTVGVIATVSLLGSVSPLIRYLIKVPREFINDYLFNFPDTSIAWSFVLALLAAALTARKRIAWLLLLGNMILAAALNVADIAAGDNTAAEIFGENLGFAVHIVAIVLLVLAYREFWAKVRKGALVKAAAVLVAGDVVGILVSWGLVELFPGTLARQDRLPYVVNRVVGFALADPDLFTGRPHVFLNAIFGLFGALALIMATIVLFQSQRAENALTGEDESAIRGLLELYGKNDSLGYFATRRDKSVVFAQSGRAAITYRVEIGVCLASGDPIGDPRAWPQAVDAWLGLCQTYGWAPGVMGASTQGARTYREAGLNALELGDEAILRTSEFKLSGPDMRGVRQAVTRARRAGLTVRIRRHRDISPEAMADTIARADAWRDTQTERGFSMALGRLGDPADGDCLLVEAIDRDGSVVAMLSLVPWGTTGVSLDLMRRSPSSPNGTIELMVSELALNAESLGITRISLNFAMFRSAFEQGAQLGAGPVARLWRGLLLFFSRWWQLETLYRSNMKYQPDWVPRYACYEDARLIPRVGVASVIAEGFLVLPFSRRDKVHTGHHPAVPARLAQSGLLHHDGSAPDVSGLRPERTDAEEARSRLPEQVRVRLAKLKVLQRNGVDAYPVGCPPSHTVAQALDADDQQDITVAGRILRIRDFGGVLFAQLRDWSGEMQVLLDNSRLERGRTADFTAAIDLGDLVEVSGQMGFSKKGTRSLIVTDWRMIGKCLRPLPNKWKGLTDPEARVRTRYVDLAVNPESRELIAARSEVLRSVRQTLFAKGFIEVETPILQQIHGGATARPFVTHINTYDMDLFLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHADYRVWIDGCRELIQNAAQAAHGEQTVLRPGADGRLQPVDISGIWAVKTVHDAVSEALGEQVDPGTSLSTLRKLSDAARIPYRAHWDAGAVVLELYEHLVEDRTEEPTFYVDFPTSVSPLTRPHRSRPGVAERWDLVAWGVELATAYSELTDPVEQRRRLQEQSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRLVMLITGRSIRETLPFPLAKPH
What is the function of this protein?
Catalyzes the production of L-lysyl-tRNA(Lys)transfer and the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge.  LPG synthesis contributes to the resistance to cationic antimicrobial peptides (CAMPs) and likely protects M. tuberculosis against the CAMPs produced by competiting microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Lysylphosphatidylglycerol biosynthesis bifunctional protein LysX.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ARADH_SACS2
Sequence: MENVNMVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLPIILGHENAGTIVEVGELAKVKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQTTNGGFSEYMLVKSSRWLVKLNSLSPVEAAPLADAGTTSMGAIRQALPFISKFAEPVVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFALELGADYVSEMKDAESLINKLTDGLGASIAIDLVGTEETTYNLGKLLAQEGAIILVGMEGKRVSLEAFDTAVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYIIKVPLDDINKAFTNLDEGRVDGRQVITP
What is the function of this protein?
Participates in a pentose oxidation pathway that converts D-arabinose to 2-oxoglutarate (PubMed:16849334).  Catalyzes the NADP-dependent conversion of D-arabinose to D-arabinono-1,4-lactone (PubMed:16849334, PubMed:17610898).  In vitro, can also use L-fucose, L-galactose and D-ribose (PubMed:16849334, PubMed:17610898).  Shows highest activity with L-fucose, in combinaison with NAD, and lower activity toward L-galactose and D-ribose (PubMed:16849334, PubMed:17610898).  When acting on its physiological substrate, D-arabinose, shows a clear preference for NADP over NAD (PubMed:16849334).
What are the official names of this protein?
D-arabinose 1-dehydrogenase (NADP(+)), AraDH, D-Ara dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: UBE2C_HUMAN
Sequence: MASQNRDPAATSVAAARKGAEPSGGAARGPVGKRLQQELMTLMMSGDKGISAFPESDNLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILKEKWSALYDVRTILLSIQSLLGEPNIDSPLNTHAAELWKNPTAFKKYLQETYSKQVTSQEP
What is the function of this protein?
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination.  Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis.  Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 C, (E3-independent) E2 ubiquitin-conjugating enzyme C, E2 ubiquitin-conjugating enzyme C, UbcH10, Ubiquitin carrier protein C, Ubiquitin-protein ligase C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: SAU26_ARATH
Sequence: MALVRSLFSAKKILGGSLVKTSKAPPKGFLAVYVGESQKKQRHFVPVSYLNQPLFQDLLSKCEEEFGFDHPMGGLTIPCPVDTFISITSQLQG
What is the function of this protein?
Provide a mechanistic link between auxin and plasma membrane H(+)-ATPases (PM H(+)-ATPases, e. g.  AHA1 and AHA2), and triggers PM H(+)-ATPases activity by promoting phosphorylation of their C-terminal autoinhibitory domain as a result of PP2C-D subfamily of type 2C phosphatases inhibition, thus leading to the acidification of the apoplast and the facilitation of solutes and water uptake to drive cell expansion (By similarity).  Functions as positive effectors of cell expansion through modulation of auxin transport (By similarity).  Involved in thermo-responsiveness of plant architecture (PubMed:31127632).  Enhances plasma membrane H(+)-ATPase (PubMed:31127632).  Probably involved in light intensity mediated root development (PubMed:31325959).
What are the official names of this protein?
Auxin-responsive protein SAUR26, Protein SMALL AUXIN UP RNA 26.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PQQC_XANCB
Sequence: MTALLSPDQLEADLRAIGARLYHDQHPFHALLHHGKLDRGQVQAWALNRFEYQRCIPLKDAAILARMEDPALRRIWRQRILDHDGNSPSDGGIARWLHLTDALGLPRELVESGRALLPGTRFAVQAYLHFVREKSLLEAIASSLTELFAPNIIGQRVAGMLQHYDFVSPEALAYFEHRLTEAPRDSDFALDYVKQHADTIEKQQLVKAALHFKCSVLWAQLDALHVAYVSPGVVWPDAFVPERDSKRAAA
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: IWR1_SCHPO
Sequence: MPLPVLRVKRKASEDPVNALYLELGNNPNSVSSTKRRKFAGRYYFKLSQTLKQDDRYIQINDESSEPTHEDVRNIHSHTKISSLKKNNYGIPVVQTSEDVVKAPTHMDLGSRENTKGILSFSSPRYTIQNLPSTQSNRVFDAIRVEQGHTTYHPHPQLDSMIQEYLSNGDLPLQQSTEDYVYDIYEASSKEPNKPTFAYGVIDALSIPDAFRSSLEQELVSETVDSDKDDPLHDEIDEDSNAESFYQNSYPDEDEWQDSSENDEFAYSDDAEQDFYD
What is the function of this protein?
Directs RNA polymerase II nuclear import.
What are the official names of this protein?
RNA polymerase II nuclear localization protein iwr1.
What is the protein family that this protein belongs to?
Belongs to the IWR1/SLC7A6OS family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=shuttles between the nucleus and cytoplasm.