PharMolix/UniProtQA huggingface dataset:
Protein: CYSD_YERE8
Sequence: MDEKRLTHLRQLEAESIHIIREVAAEFGNPVMLYSIGKDSSVMLHLARKAFFPGNLPFPLLHVDTGWKFREMYEFRDHTAKAFGCELLVHRNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTELDIWQYIFLEKIDIVPLYLAKPRPVVERDGMLLMVDDDRIDLQPGEVITQKMVRFRTLGCWPLTGAVESEAQTLPAIIEEMLISTTSERQGRMIDRDQSGSMELKKRQGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: COX2_CASBE
Sequence: AICSLVLYLLTLMLMEKLSSNTVDAQEVELIWTILPAIVLILLALPSLQILYMMDEIDEPDLTLKAIGHQWYWTYEYTDFKDLSFDSYMVPTSELPSGHFRLLEVDHRVVVPMESPIRVIITAGDVLHSWAVPTLGVKTDAIPGRLNQTSFITTRPGIFYGQCSEICGANHSYMPIVVESTPLTHFENWSSLLSISSSL
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KLF3_CAEEL
Sequence: MLKMEQSAPPRYEEDWADVYEFIERDSSRKNVPAIEAIERRLAFSPLITPNPGAKQFAPIHVPGREPPRMLLPPTPHFQAPFSPHPPPVQQVPSYSPPHAPPSYETYPEVYYPPHIICNPYDVPTTSDRNPPYYTEVTTVSAVTLHSMTPPTHKIETPPSSPENSFGPLASQLPAIKMEIPMHPLPHNGELDSTRSSPSSTTSSERSPLQRKSRIESNKRNPTDKKFVVHACTYPGCFKKYSKSSHLKAHERTHSGEKPFVCKWQNCSWKFARSDELTRHMRKHTGDKPFRCSLCDRNFARSDHLSLHMKRHSTI
What is the function of this protein?
Probable transcription factor which regulates lipid catabolism, storage, and secretion, probably by modulating genes involved in fatty acid desaturation and beta-oxidation, and lipoprotein assembly and secretion (PubMed:19427851, PubMed:23639358).  Involved in reproduction, perhaps indirectly (PubMed:19427851, PubMed:23639358).
What are the official names of this protein?
Kruppel-like factor 3.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: WHIA_GEOSW
Sequence: MSFASETKKELTNLEVKPCCLKAELSALLRMNGLLSFSNQQILVDVQTENAAIARRIYTLLKKGYTVTVELLVRKKMRLKKNNVYIVRIIDGAHELLKDLKILKEDFSLIRVISPELVKKKCCKRSYLRGAFLAGGSVNNPETSSYHLEIFSLYEEHNNSLCELMNSHFFLNAKTLERKKGFITYLKEAEKISEFLNIIGAHQALLRFEDIRIVRDMRNSVNRLVNCETANLNKTIGAALRQVENIRYIDETIGLSALPDKLREIAELRMMYQDVTLKELGELVSGGKISKSGINHRLRKIDEIAERLRAGKPVDFHKSL
What is the function of this protein?
Involved in cell division and chromosome segregation.
What are the official names of this protein?
Probable cell division protein WhiA.
What is the protein family that this protein belongs to?
Belongs to the WhiA family.
Protein: PHNC_STAEQ
Sequence: MSQIEFKDVSKVYPNGHVGLKDINLNIEKGDFAVIVGLSGAGKSTLLRSVNRLHDISKGDITIEGQSITKARGKKLLEMRRSIGMIFQHFNLVKRSTVLRNVLSGRVGYHPTWKMILGLFPKEDKVKALDALERVNILDKYDQRSDQLSGGQQQRISIARALCQEPTIILADEPVASLDPLTTKQVMDDLKKINEELGITILINLHFVDLAKEYGSRIIGLRAGELVYDGPASEANDEVFNHIYGRSIKDDEKLGVE
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: SYI_MYCPA
Sequence: MTDNLGFQADREAQPADSVQTYPKPAGGAPDFPALELEVLDYWARDDTFRASIARRDGAEEYVFYDGPPFANGLPHYGHLLTGYVKDIVPRYRTMRGNKVERRFGWDTHGLPAELEVERQLGITDKSQIDDMGIAAFNDACRESVLRYTDEWRAYVTRQARWVDFDHDYKTLDLPYMESVIWAFKQLWDKGLAYEGYRVLPYCWRDETPLSNHELRMDDDVYPSRQDPALTVGFKVVGGELDGAHLLIWTTTPWTLPSNLAVAVHPEVTYVQVRSGDRRFVLAQPRLAAYARELGPEPEILGSYRGAELLGTRYLPPFPYFMDNPNAFRVLAGEFVTTEDGTGIVHLAPAYGEDDMAVADAAGIAPVTPVDSNGRFDAAVPDYQGLNVFDANPQIIWDLKNGSGAAAANAPVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTRFRDRMVELNQQITWYPEHVKDGQFGKWLAGARDWSISRNRYWGTPIPVWKSDDPAYPRIDVYGSLDELERDFGVRPDNLHRPYIDELTRPNPDDPSGRSTMRRIPDVLDVWFDSGSMPYAQVHYPFENRDWFETHYPGDFIVEYIGQTRGWFYTLHVLATALFDRPAFKTCVAHGIVLGSDGQKMSKSLRNYPDVSEVFDRDGSDAMRWFLMASPILRGGNLIVTEQGIRDGVRQVLLPFWNAYSFLALYAPKIGTWRTDSPQVLDRYILAKLAELRDDLTREMDACDISRACEQLRQFTEALTNWYVRRSRSRFWSEDADAIDTLHTVLEVTARLAAPLLPSVTELVWRGLTGGRSVHLTDWPRSGELPADPGLVAAMDQVREVCSAASSLRKAKKLRVRLPLPKLTVAVENPQHLAPFVDLIADELNVKSVELTDAIDTYGTFELTVNARVAGPRLGKDVQAAIKAVKAGEGVVNADGTLTAGPAVLRPEEYSSRLVAADPEFTAALPNGAGLVVLDGTVTPELEAEGWAKDRIRELQELRKSTGLDVSDRISVVMSVPAGRAEWARTHRDLIAGEILATRFEFGEPADPVAIGDGVRVSISKV
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_CUPNH
Sequence: MAIEGVLNEGFVTTTADKLINWTRTGSLWPMTFGLACCAVEMMHAGAARYDMDRFGVIFRPSPRQSDVMIVAGTLCNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALIYGVIQLQNKIKRTNTIARKG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CH60_TROWT
Sequence: MAKKITFNEDARRGLERGLNTLADTVKVTLGPRGRNVVLEKKWGAPVITNDGVTIAKEIELDDPYEKIGAELVKEVAKKTDDVAGDGTTTSVVLAQAMVREGLKNVAAGADPISLRRGIEKSVAAVSKALLTSAKEVETEAEIAACASISAGDPQIGDIIAQALEKVGKEGVVTVEESNTFGTELEITEGMRFDKGYLSAYFVTDAERQETVFENPYILICDSKISSVKDLLPVVDKVIQSGKQLLIIAEDVDGEALATLVVNKIRGIFKSVAVKAPGFGDRRKMMLQDIAVLTGGQVISEEVGLKLENATLDLLGRARKVVVSKDETTIVDGAGSSDQIAGRVSQIRKELENSDSDYDREKLQERLAKLSGGVAVIRSGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGAALLQSGTSALKDLQLTSEEAVGRNIVRSAIEAPLRQISLNAGLEPGVVVGKVSSLPQGHGLDASTGEYVDMLSRGISDPVKVTRSALENAASIAGLFLTTEAVVAEKPEPKPAPGPADPGAGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SDHF2_AEDAE
Sequence: MSLLRVTRSSGHLSAVCRLPARSISTTSILLVPSNEGNKPPTPMIDLEDKSLPIPIYKEKKNEPLQLQKSRLLYQSRKRGMLENGLLLSTFAAKHLESMDVKQTKLYDQLINMPTNDWDIFYWATGVKPTPAEYDNEIMALLKDHVKNANREKRICQPNLY
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2, mitochondrial, SDH assembly factor 2, SDHAF2.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL3_ANADF
Sequence: MATGLLAKKLGMTQIFTAEGDCIPVTVLEAGPCTVVRRKTAEKDGYDAVVIGWGEVDEKHAHRLTKPEVGVFKKAGTPVFRHVKEIRVKDAKLLGELKAGDVLTVDKVFKQDQRIDVAGVTKGRGFTGVMKRWNMHGAARDSSTTHEHHRHVGAIGQRKTPGKVWKGKHLPGHYGVDNVTIQNLTIVGVEADKNLLLVKGAVPGHNDGLLFVNTAVKGQPRVKKVQEVRARAKPKV
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GRE2_ECOLI
Sequence: MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHLDKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDLADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMTSGDAHLAVNFPLLLEKGLDGLREEVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSEHIERFAALAREMAATETRESRRDELLAMAENCDLIAHQPPQTFWQALQLCYFIQLILQIESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSHSKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGMSNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKWGYRCTGMSFINFARVMLAALEGGHDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQIRYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGIANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDTVDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRKAHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQKLMILLRTFFEVHKGWHIQYNIVSRETLLDAKKHPDQYRDLVVRVAGYSAFFTALSPDAQDDIIARTEHML
What is the function of this protein?
Probably shows dehydratase activity.
What are the official names of this protein?
Probable dehydratase YbiW.
What is the protein family that this protein belongs to?
Belongs to the glycyl radical enzyme (GRE) family.
Protein: SYR_RHIEC
Sequence: MNLFTDFEARIKTALEQIDLVREKRSELDFGRIAVEPPRDASHGDVATNAAMVLAKPLGTNPRALADVIIAKLKEDADVADVSVAGPGFINIRLAVGYWQRLLASIIGAGIDYGRSSLGEGRTVNVEYVSANPTGPMHVGHCRGAVVGDALANLLAFAGYGVEKEYYINDAGSQIDVLARSVFLRYREALGERIGEIPSGLYPGDYLVPVGQSLAADYGVRLHNMPEEEWMPIVKDRTIDAMMAMIREDLAALNVHHDIFFSERTLHANGAAAIRTAINDLTFKGYVYKGTLPPPKGQLPEDWEDREQTLFRSTEVGDDIDRPLIKSDGSYTYFAADVAYFKNKFDRGFEEMIYVLGADHGGYVKRLEAVARGVSDGKAKLTVLLCQLVKLYRNGEPVKMSKRSGDFVTLRDVVEEVGRDSVRFMMLYRKNSEPLDFDFAKVTEQSKDNPVFYVQYAHARCMSVFRQAKEAFAGLDVSPEDLAKAVAGIEDPAELQLVAKLAEFPRIIESAAQSQEPHRIAFYLYDLASAFHAHWNKGKDQPELRFVNDKNRESTIARLGLVYAVASVLKSGLAITGTAAPDEMR
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAER_LITPE
Sequence: QQDYTGWMDF
What is the function of this protein?
Induces contraction of intestinal smooth muscle in isolated guinea pig ileum.
What are the official names of this protein?
Caerulein.
What is the protein family that this protein belongs to?
Belongs to the gastrin/cholecystokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: MRAY_KORVE
Sequence: MLYWLLYEKAFLLHNFTPFRIFRYLTFRTAFASLTALFMGLIIGPAVVRRLREFQIGQYIREEGPKSHQKKSGTPTMGGVLITIAIIVPTLLWADLSNKFVWIAMLATIAFGAIGFTDDYLKVANRRNLGLTARAKMGLQILVAILVAISLVLVQRHGHYNTHLIVPFIKSFHPDLEISKLATYPHIWIIAYIPFLAFVAIVLVGSSNAVNLTDGLDGLAIGCTVIAAGALTVLTYVSGHAQFADYLGLSRMPEVGELSIFCGAMVGSAIGFLWYNAHPAEVFMGDVGSLALGGAIGTVAVIIKQELLLPFIGGVFVLEALSVILQVGSYKLRKKRIFKMAPLHHHFELLGWSESKIIVRFWIASLVFALFALTTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HSLO_PARMW
Sequence: MADRLVRATAAGGGIRLVAVSTTETVREARRRHDLSFLSTVMLGRAMAAGLMLASSMKVRHGRVNLRLGSDGPLRGLMVDAGRDGTVRGYVGDNTLELDPVIDADGNHSFNFKAAAGTGYLHVMRDDGKGEPFNSTVELVSGGIGDDVASYLLHSEQTPSAVFVGERISSQQLHSSGGLLVQILPKAAEEPALVELLDQRCREIEDFSGRLDRCGDQLEDLLVDVFPDLDPRPLEDADASQSVNFHCRCTRERSVAALLLMGRTELADMLEKDGGAELNCHFCSNNYVVSGPELEGLIAELAAAS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SL9A_ECHCA
Sequence: DCLPGWSSHEGHCYKVFNEYKTWKDAEKFCKKQGKSGHLVSVESSEEGDFVAKLISENLEKSHSIDFVWTGLTYKGRWKQCSSEWSDGSKIKYQKWGKQQPRKCLGLEKQTEFRKWVNLYCEEPQRFTCEI
What is the function of this protein?
Anticoagulant protein which binds to coagulation factor IX (F9) and coagulation factor X (F10) in the presence of calcium.  It may bind the gamma-carboxyglutamic acid-domain regions of factors with a 1 to 1 stoichiometry.  The dissociation constant (K(d)) are 6. 6 nM for factor IX (F9) and 125 nM for factor X (F10).  Does not bind carbohydrates.
What are the official names of this protein?
Snaclec coagulation factor IX/factor X-binding protein subunit A, IX/X-BP subunit A, ECLV IX/X-BP subunit A.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: ESSD_STAAE
Sequence: MHDMTKDIEYLTADYDNEKSSIQSVIDAIEGQDFLDVDTTMDDAVSDVSSLDEDGAISLTSSVVGPQGSKLMGYYQNELYDYASQLDSKMKEIIDTPFIEDIDKAFKGITNVKLENILIKNGGGHGRDTYGASGKIAKGDAKKSDSDVYSIDEILKSDQEFVKVIDQHYKEMKKEDKKLSKSDFEKMMTQGASCDYMTVAEAEELEEQKKKEEAIEIAALAGMVVLSCINPVAGAVAIGAYSAYSAANAATGKNIVTGRKLSKEERIMEGLSLIPLPGMGFLKGAGKSLMKLGFKGGEKFAVKTGLQKTMQQAVSRISPKMGMMKNSVLNQSRNFAQNTHVGQMLSNMRGQATHTVQQSRNWIGQQAQNVKRIVNNGLDKEIAHPFKQQLAPAGMGGIKFAETTTLRNMGQNIKRAVTPQNHVTHGPKDSMVRSEGKHSISSHEMNSSKYVESPNYTKVEFGEHYARLRPKKLKANIEYTTPTGHIYRTDHKGRIKEVYVDNLSLKDGDRNSHAQRTVGGEDRLPDDDGGHLIARMFGGSKDIDNLVAQSKFINRPFKEKGHWYNLEKEWQEFLNSGKEVKNIKMEVKYSGNSQRPTIFKVEYEINGERNIRRILNK
What is the function of this protein?
Component of the type VII secretion system (Ess) (Probable).  Plays a role in Ess secretion during infection.  Required for the efficient secretion of EsxA.  Required for abscess formation and staphylococcal persistence in host tissue (PubMed:21278286).  Possesses a toxic DNase activity that is modulated by EssG by forming a nuclease toxin-antitoxin pair.  This nuclease toxin targets competitor bacteria (By similarity).
What are the official names of this protein?
Type VII secretion systems protein EssD, Ess-associated gene D, Nuclease toxin EssD.
What is the protein family that this protein belongs to?
Belongs to the EssD family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Released from the cell in a form that is immediately active while EssG partner protein remains in the producing cell where it may potentially serve further protective functions.
Protein: LPXB_SYNC1
Sequence: MHEVKQPRRIMVVTGEASGDLHGAHLIEAAGKVDPGLSFFGVGGACMAKAGCEILIPGEDLAVMGLVEVLGHFPTIWRAFRKLKKILHGPQRPDALVLIDFAEFNLLLAAQAKKAGVPVLYYVSPQVWAWRRGRVRRIASVVDRLAAIFPFEPELYQGLDIDVEYVGHPLLDEFAITCERDAFLRRLGLDPARQVIGLFPGSRKNELKYIAETILQSAVKLREKHPDAQFLLPVASSFRRQDIEALVAPYGLPVTVVDEPIYDVINACDAVISVSGTVTLQVALVGTPMAIVYKMAPLSFAIGKRLIRVPHIGLANIVAGRGVVKEFIQEDATPAMISREIDAILTDAEYNRSIRGGLATVQQRMGEGGCAARVARMVSELCREIPGKERMV
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: COAD_RHOOB
Sequence: MTGAVCPGSFDPVTNGHLDVIGRAAAQFDEVIVTVMVNKNKRGLFTVEERIEMLEDSTADLPNVRVSSWHGLLVDYAKQQGITAIVKGLRGANDFDYELQMAQMNQKLSGVDTLFIPTNPTYSYLSSSLVKEVATFGGDVSDMLPEKVHARLLTRIAERAAESS
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y6946_DICDI
Sequence: MDDDEFVFIESNPTQSTWVDVKKSQQQQQQQPQAPPQQQQQQILPVYRNLNPLVDENDGFTYQQQQLYLQQQQQFCQQQLLLEQQQQQQLLLKQQQQQLLLEQQQQQLLLKQQKQQLLLEQQLLLEQRQQQQQKVPIPIAQVPASTLVVESKQEEKIQEEQEVPVIVSIINSPPPPQEEEKPQLSKKEEPEWLKGKDKAPYISTSTSDVKYTSNVVSNKPYTTIKSSTSYSSVSGSGGSGIRRISLAELNGNSKPYTSSNATNKPFTTASKSTNSYSFSF
What are the official names of this protein?
Uncharacterized protein DDB_G0286393.
Protein: ACCD_CHLSY
Sequence: MKEFFRLSRKGFTGREDQDSAQIPDDLWVKCSSCRELIYKKQLNDNLKVCPKCGHHMRLSAHEWLGLLDVGSFREMDANLLPTDPLGFVTDEESYAAKLAKTQQRTGMADAVIAGIGAISNMQICVAVADFSFMGASMGSVYGEKMARSAERAAELGVPLLTINTSGGARQQEGVIGLMQMAKVTMALTRLADAGQPHIALLVDPCYGGVTASYPSVADIIIAEPGANIGFAGKRLIEQIMRQKLPAGFQTAEFMLEHGMIDMVVPRSEMRDTLARILRLYRQRSTSPAKAELAGRRATLPQPIM
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL14_GLUOX
Sequence: MIHPETNLDVADNSGARRVQCIKVLGGSKRKTASVGDVIVVSVKEAIPRGKVKKGDVHQAVIVRTSYPVRRADGSAIRFDKNAAVLLNKQQEPIGTRIFGPVVRELRARKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: YFGG_ECO57
Sequence: MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHHQSKKEAQQSTLSVESPVQR
What are the official names of this protein?
Uncharacterized protein YfgG.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: F16A2_METPP
Sequence: MTRRISLTQYLVEEQRERGRIPAQLRLLLEVVARACKSIAISVNKGALGGVLGSAGSENVQGEVQKKLDIIANEVLIEANEWGGALAAMASEEMDSIYVVPNRYPQGEYLLLFDPLDGSSNIDVNVSIGTIFSVLKKQSDTPGVSTQDFLQPGSAQVAAGYCVYGPQTTLVLTVGDGVAMFTLDREQGSWVLTTDEVRIPEDTREFAVNMSNQRHWAPPMQRYIDECLQGKDGPRGKDFNMRWVASMVADVHRILCRGGVFMYPWDKREPAKAGKLRLMYEANPMGFIVEQAGGAATNGKQRVLDLQPSQLHERVSVILGSKNEVERASAYHREAG
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 2, FBPase class 1 2, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_BURO1
Sequence: MQTSLLKPKIIAVESLGENHARVVMEPFERGYGHTLGNALRRVLLSSMVGYAPTEVTIAGVVHEYSTLDGVQEDVVNLLLNLKGVVFKLHNRDEVTVTLRKEGEGVVTAGDIELAHDCEVINPNHVIAHLSKGGKLDVQIKIEKGRGYVPGNVRRYGEDTAKIIGRIVLDASFSPVRRVSYAVESARVEQRTDLDKLVMNIETSGVITPEEAIRQSARILVDQLSVFAALEGTETAAEAPSRAPQIDPILLRPVDDLELTVRSANCLKAENIYYIGDLIQRTENELLKTPNLGRKSLNEIKEVLASRGLTLGMKLENWPPAGLDK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: LEPA_STAAS
Sequence: MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.