PharMolix/UniProtQA huggingface dataset:
Protein: RS8_GEOSL
Sequence: MSMTDPIADMLTRIRNANMARLQKVDIPSSNLKVNLANVLKAEGFIKNYKVIADSRQGVLRVYLKYIDEKDPVINEIKRVSKPGSRVYVGSDKIPSVKNGMGVAILSTSKGLITDKSAREAGVGGEVLCTVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RNH3_BACVZ
Sequence: MSHSVIKVSASAMEQMKQSYAGSLTPAVPQGAVFQAKPPGCTITAYRSGKVLFQGKNAGTEAARWGTAEAPKAKKTVKKAADPLYAPPAGIASMSVIGSDEVGTGDYFGPITVACAYADKTKLSLMKELGVKDSKDLKDPQIIEIAKLLIKTIPYSLLVLKNEKYNQMQEKGMSQGKMKALLHNQAISNLLRKMNGVKPEAILIDQFAEPGIYFKHLSGRDIVKEKTFFSTKAESIHLSVAAASIIARYSFLIEMDKLSREAGMTIPKGAGPHVDEAAAKLIINKGEGALRTFTKLHFANTQKAKRLVERKRS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HIII, RNase HIII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family. RnhC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_POLNA
Sequence: MLAKRIIPCLDVTGGRVVKGVNFVELRDAGDPVEIAARYNDQGADELTFLDITATSDGRDLILHIIEAVASQVFIPLTVGGGVRTVEDVRRLLNAGADKTSFNSAALANPQVITDASAKYGAQCIVVAIDAKRRSDEDALLRGAGWDVYSHGGRKNTGLDAVAWAVEMAQRGAGEILLTSMNRDGTKSGFDLELTRAVSDAVSVPVIASGGVGNLDHLADGVQLGGADAVLAASIFHYGEYTVAQAKRHMASRGIPVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_ALTMD
Sequence: MTLFEIIILAIIQGVTEFLPISSSGHLLLPAELLGWVSQGLAFDVAVHVGSLLAVMIYFRQEIGQMTVAWVTQGFSKQQSTDSKLAWYVIVGTIPAVIIGFLMKGWIEENARTALVIAGTTIIFGLLLWYADATAKREQELEGLTLKQAIYIGLAQVLALIPGTSRSGITMTAGLMLGLKREACARFSFLLSIPVILGAGLLATLDLLSANEAVDWYALLYGAAFSFVSAYLCIYLFLSWIARIGMLPFVIYRLALGAVLLWFVFA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CRCB_ANASK
Sequence: MARLLLVCLGGALGSGARYLTSAWALRAFGPDFPRGTLLVNVSGSFLLAGIMTASLQSEAVPPDLRLFLAAGVMGGFTTYSSFNYETLALVEQGRLAAAAAYLLATVVGCLVAAFAATLLVRWLAG
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RINI_PANTR
Sequence: MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQSPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCNLSAASCKPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNKFLLELQISNNRLEDAGVQELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS
What is the function of this protein?
Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG.  May play a role in redox homeostasis (By similarity).
What are the official names of this protein?
Ribonuclease inhibitor, Ribonuclease/angiogenin inhibitor 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2C_YEAST
Sequence: MTKDAVNLDAYTVSFMPFYTEYQGPTEEFKDYKFEDTIYFRGKELKREKSATPSSSDNTTSNTFSNGAILSGNTITGKIVSVNNYEREGTDRNELARLQELISLIDVINQ
What is the function of this protein?
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids.  Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication.  Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
What are the official names of this protein?
Ribonuclease H2 subunit C, RNase H2 subunit C, Rnh2C, RNase H(203), Ribonuclease HI subunit C.
What is the protein family that this protein belongs to?
Belongs to the RNase H2 subunit C family. Highly divergent.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: IF2G_HALS3
Sequence: MADEHRQPEVNIGLVGHVDHGKTTLVRALSGEWTDQHSEEMKRGISIRLGYADATLRRCPDCDEPECYTVAETCPEHDTATEIERTVSFVDAPGHETLMATMLSGAALMDGAVLVVGANEPVPQPQTEEHLMALDIIGIENIVIAQNKVDLVDAEEARQNYEEIQAFVEGTVAEDAPVVPVSAEQEINVDLVIDALQTEIATPDRDPSADPLLYAARSFDINRPGTEWGGLLGGVIGGSLVDGELEAGDELELRPGREVEEGGKTEWRPVTTDVRSLQAGGEDVDSASPGGLLGVGTGLDPSLTKGDALAGQVAGPPGSLPPTWESFEMDVDLLERLVGAADGEQIDDISTGEPLMLTVGTATTVGSVTSARDGECEVALKRPVCAPAGAKIAINRRVGARWRLIGVGTLTESE
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit gamma, aIF2-gamma, eIF-2-gamma.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
Protein: SYFB_DESPS
Sequence: MKFTLNWLQKYVDTTGLTPTEIADKLTMLGLEVDSVAPIFEELAALKTGLVISCEKHPDADKLSLCQVQVGDDTHQIVCGAPNVREGLAVTVALPGAVLPGNFKIKKSKVRGIASAGMLCSERELGIGEDHDGIMELPEGMAHGQRFIDAMELSDTFIEVDLTPNRPDCASVIGTAREIAGKIGRPLQIPVKDRQIEAESRDFSVEVESSELCPRYTAKLIKNVTVGKSPWWLRKLLVSVGMRPINNIVDITNFVMLEYGQPLHAFDFKKVAGNKIVVRLPRENETEITTLDGTKREISAEMLLICDADKPIAVAGVMGGANSEIDAESTDILLESACFNPVSVRKTARNLKLPSEASYRFERGVDPGGVVNALDRAAELIAEIAGGALCSEGIDNYDGKKAVEVQRFSISRTSSLIGVEFSGEELTAMLTSIEMVVEKDPENEDILLVTAPTFRIDIEREADLVEEIARIYGYDNVPTATPLVALSYPEQDDDRLKRYPLALKLTRIGFNEAINYSFVTAQHADMLQLSEQDYRRKVVTLLNPLSEEQAVMRACLLPSLLENVKRNISFQKTAVKLFEIGKIFLAQGEDVQPIERQCITGVLSGNKFGESSSLYFKSANVDIFDAKGTVEFILSEMGLTDLANNEKIEFTVPPEGAREPFSTQDYALTIHLGPNVLGTIGKVEEEVLKSFGIKHEVYYFDLNFDALCALSPQTKAFSSLPVYPAVKRDIALVVPASISAGELLATVRSSRDKLMEYAEIFDVFEGGKIQKGYKSVAVSITYRSQTKTLTEKNVEKSHSKIVSLLTDRFGGSFRDA
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PO24_POPJA
Sequence: AYADDLILFANDHRAANRLLKVATEFFRERGLALNATKSAALSVGVVPGKKQLYTHTKNLFYVGGKAIPQLTPDDYFKYLGSRYNFSGQVRPSVELLKTQLARVQSAPLKPAQKLTMIRDHVVARFLSCLQSVRVTLKALKDADRLVRLSVRKVLHLNKSSPDAYIHAPIREGGLGIISLRAHIPAIMRSRLFKIATTADPLTATVLQIPAVEKFYQTLLRWTEGNGGSTTNIRKEWGRKLQESYSGNGLRQGNTSGVSGDWLRNPPNFWSGADYIDAVRLRGNLLPTRGIPSNPPHERKCRAGCNKTESLSHVLQGCPLTHWHPIRRHDRVAGRLRQIAEKKGWMVEEEMRLRLADGSLRKPDLVMAQGDTIVVCDVTIVWEGPNPLTMAYHQKVAYYSQQPVLDAIHDRFPGRSVVVLALVLGARGTWCDQNNAITDTLSLSRAQNSLINNCINGSIIVHREFMRTSFTRATGGRGRGDI
What are the official names of this protein?
Retrovirus-related Pol polyprotein from type-1 retrotransposable element R2, Retrovirus-related Pol polyprotein from type I retrotransposable element R2.
Protein: MOA2_CAEEL
Sequence: MALPGERFHVLAQLEHLQSKYTGTAMRHEPSRMDCESAPRHSRLSNVSSRNEHVYCRCGEREPSSNPLQSDKSHDSAVWTASREESS
What are the official names of this protein?
Protein moa-2.
Protein: RL7_DECAR
Sequence: MAISKEDILEAVGSLTVMELNDLVKAFEEKFGVSAAAVAVAGPAGAGAAAAEEQTEFTVMLTGAGDKKVEVIKVVRAATGLGLKEAKDLVDGAPKAVKEGVSKADAEALKAQLEAAGAKVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: CTXL1_LEIHE
Sequence: CGPCFTTDHQMEQKCAECCGGIGKCYGPQCLCNR
What is the function of this protein?
Chloride channel ligand.  Potently and reversibly inhibits CFTR chloride channels when the channels are in the interburst closed state.  May also interact with chloride channels (probably ClC-3/CLCN3) and MMP2 at the surface of glioma cells.  This complex may be then internalized via caveolae, thus inhibiting the chloride channels necessary for cell shrinkage and tumor propagation.
What are the official names of this protein?
Toxin GaTx1.
What is the protein family that this protein belongs to?
Belongs to the short scorpion toxin superfamily. Chloride channel inhibitor family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRMB_ROSDO
Sequence: MSKQTRPHRNFYGRLKGKSLKAAQKRYLDEDLAALSPGAVGWEENPDRRPLDLPGLFEGKPVWLEIGFGGGEHLVHQAAQNPDIGIIGAEPYINGVAMLLGKIRRAGVENLAVHAGDARDLMDVLPAASIDRAFLLYPDPWPKARHHRRRFVTAEHLDPLARALKPGSVFRVATDIEDYVRQTLQEVPKHGFKWLANAPQDWRRPWPDWISTRYEQKALREGRTPHYLTFVRE
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: ARGB_FRACC
Sequence: MNAPTRTPPPSNGGHGSTGSTGSTGDAAPGGGTGRGPAATARGHAALAKTQVLIEALPWLSRFQGATIVVKYGGNAMTEPALREAFAADVVFLRHSGLRVVVVHGGGPQITAHLERLGVPSTFVGGLRVTTPQTMDVVRMVLLGQVNRDVVGLVNDHGPFAVGLSGEDANLFTARRRPAIVDGREVDVGLVGDIVEVRPETINALLGSGKVPVVASVARGVDGGVYNVNADTAAAELAVALGATKLVVLTDVEGLYADWPASDEVISELSITELEQLLPSLTAGMIPKMEACRRAVRGGVPQAHVLDGRVPHAVLLEIFTDDGIGTLIMAESGTSPEPGTPPAPAARPAGIVPAGEPTGGTP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_PSYIN
Sequence: MTKVRTKISLKIGANSRIPAQIASFNGLTSDKEHIAIIFGKADECSSSPIVRIHSECLTGDVFHSSRCDCGEQLDEAIELMEKEGGIIIYLRQEGRGIGLYNKIDAYKLQSEGMDTYQANNQLGFEDDLRDFTEAGQMLAALNIRKLQLLTNNPLKVKALREYGITVDKVISTSTFIKDDNESYLRTKAKNAGHAIRFPF
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: RSMB_ECO8A
Sequence: MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQWQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQRTADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_STRGC
Sequence: MKLNVNLPHHPYDIVIENGALSQVGSWLSQLWQPQKLVVITDNRVARLYAEKVKLSLEAAGFKVFTFDFLEGEASKNLTTVNKAYEFLAKVGLTRSDGIVALGGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPWAKNMVGTFTQPDGVLIDPEVLHTLGQRELIEGMGEVVKYGLIEDKELWDELSEMDGSPESILEHAESIIYHSCDVKRKIVIEDELDNGVRLYLNFGHTIGHAIEATAGYGQVMHGEAVAIGMVQVSRVAEKQGLMPAGITEDIIHMCQKFGLPVDYQPWNENALYQALTHDKKARGNSIKLVLVPELGSANIHQIPLEEMKEFLKK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y095_BORBU
Sequence: MLDSYYYVLSSLPYIDLKSLKNYSVSDFLNNVEISLSKKDFNFLKELLEFKIDRGKSRVIDLFLNFEDTIRYTLAALRAEKLGLSKDFYLESTYFSSYYLSILKNICLKENPFEIELSFDLLKWQFLTDLEVGHEFDFEKLIIYFLKLRLFLRHNLFKEKLGIQNFDNICKNLIDKTNEKV
What are the official names of this protein?
Uncharacterized protein BB_0095.
Protein: HBOH_BURVG
Sequence: MDTHGWGSRILVGAALAALTMLGACNGDETAERNQLPVFVSGSVRTTAYDGASDDLLTAGLGKTGLASAAAPAFADPSRPTAAELRRVAIWSNYRALVDMSANGGYGRFWGPNVDLDGNDTLGEGKIAGTEYLAYADDGSGRKNVTLLVQVPASFDPAQPCIVTATSSGSRGVYGAISAAGEWGLKRGCAVAYNDKGGGNGAQELGSNTVTLIDGTLANAVLAGSASLFTANLTSGDLAAFNSRFPNRYAFKHAHSQQNPEHDWGRATLQSVEFAYWALNQQFAPLVDGSHRGVRYRAGDITTIAASVSNGGGAALAAAEQDTRRWITAVVVGEPQINVRMAPNAVVRESGRPVPSFGRPLADYATLANLLEPCAAASASLAGEPYLSALPLATTQSIRTQRCATLAAAGLVSGADTQSQAADALAQLHAAGYLADSDLLQASMWDSQAIPAIAVTYANAYTRSSVADNLCNFSFATTNAATGAVAAPAASPMPAVFGLGNGVPPTAGINLVFNTGAGVDHRLATPDASFAGALCLRQLWTNGMLDMPANVEAVRVNANLQGKPAIIVQGRSDALVPVNHASRAYVAQNSISEGGRSQLVFYEVTNGQHFDAFLPVAGFDTRFVPVHYYNVQALNLMWRHLKSGAPLPPSQVIRTVPRGGTPGAAPALTSANLPPISTAPGANAIAAGAGAIDVPL
What is the function of this protein?
Participates in the degradation of poly-3-hydroxybutyrate (PHB).  It works downstream of poly(3-hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers.
What are the official names of this protein?
D-(-)-3-hydroxybutyrate oligomer hydrolase, 3HB-oligomer hydrolase, 3HBOH.
What is the protein family that this protein belongs to?
Belongs to the D-(-)-3-hydroxybutyrate oligomer hydrolase family.
What are the subcellular locations of this protein?
Secreted.
Protein: RBL_BURIN
Sequence: VGFKAGVKDYKLTYYTPDYVTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIFKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNDIIRDASKWSPELAAACEVWKEIKFEFEAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ILVD_PHOV8
Sequence: MKNQLRSSFSTQGRRMAGARALWVANGMKKEMMGKPIIAIVNSFTQFVPGHTHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHKADAMVCISNCDKITPGMLMAAMRLNIPTVFVSGGPMEAGEWNNQHLDLIDAMIKSADASVSDEDVAQIEDNACPGCGCCSGMFTANSMNCLNEAIGLGLPGNGTILATHANRTQLFKDAAALIVKNAYKYYEEGDDSVLPRSIATRDAFLNAMTLDIAMGGSTNTVLHLLAIAHEAEVDFKMDDIDMLSRHVPCLCKVAPNTQKYHIQDVNRAGGILNILGELSKGGLLKTDVKRVDGLTLAEAVEKYNICKKEVDTEAKRIYSSAPGNKFNIKLGSQNAVYKELDTDRANGCIRDLQHAYSKDGGLAVLKGNIAQDGCVVKTAGVDESIWKFSGPAKVFDSQDAACEGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGGTSGLSIGHISPEAAAGGNIGKIVDGDIIEIDIPNRSINVKLSDEELAARPMAPVTRDRKVPKSLKAYASMVSSADKGGVRIID
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: FABH_STAAE
Sequence: MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHWADDDQDTSDLAYEASLKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGKVASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDGAGAVIIGEVSDGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPLSIDQELKNGKIKDDDTIVLVGFGGGLTWGAMTIKWGK
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_ELUMP
Sequence: MEAFAIAKFQRHGSRKVGLVLDQIRGKNVKKAEEMLPFIEKRTAELVYKTVHSAAANLEVKSGKKLDLSKVYIKEAYANIGPMSNLRRIQPGPQGRAMPYKKSMCHLTVVVSDEKGGR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DNLJ_BACFR
Sequence: MTVKEKIEQLRLQLHQHNYNYYVLNAPEISDKEFDDLMRELQDLEQEHPEYKDENSPTMRVGSDINKNFTQVAHKYPMLSLSNTYSENEVTDFYDRVRKALNEDFEICCEMKYDGTSISLTYENGKLIRAVTRGDGEKGDDVTDNVKTIRSIPLVLHGDNYPEVFEIRGEILMPWEVFEALNREKEAREEPLFANPRNAASGTLKLQNSAIVASRKLDAYLYYLLGDNLPTDGHYENLQEAAKWGFKISPLMRKCQTLQEVFDFINYWDVERKNLNVATDGIVLKVNSLKQQRNLGFTAKSPRWAIAYKFQAERALTRLNMVTYQVGRTGAVTPVANLDPVQLSGTVVKRASLHNADIIEGLDLHIGDMVYVEKGGEIIPKITGVDTSVRFMIGEKVKFITHCPECGSKLIRYEGEAAHYCPNETACPPQIKGKIEHFISRKAMNIDGLGPETVDMFYRLGLIHDTADLYRLTTDDIRGLDRMGDKSAENIIKGIMQSKEVPFERVIFALGIRFVGETVAKKIAKSFKDIEELENADLETLINIDEIGEKIARSILNYFANESNRKLVDRLKTAGLQLYRPEEDLSGHTDKLAGQSIVISGVFTHHSRDEYKDLIEKHGGKNVGSISSKTSFILAGDNMGPAKLEKASKLGIKIMNEEEFLKLIS
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: RNH_DESVM
Sequence: MTMKNVQAFTDGSCLGNPGPGGWAAVLRCNGSERELSGGFALTTNNRMEILAVIEALALLKEPCGVDLYTDSQYVRNAVEKKWLAGWRRNGWKTSDKKPVKNRDLWERLQPLLDLHQVRFHWVRGHSGHPENERCDVLARTQASSRGLPPDTGYRE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH60_LEUMM
Sequence: MAKELKFSEDARAKMKAGVDKLADTVKTTIGPKGRNVVLEQSYGAPTITNDGVTIAKAIELEDHFENMGAKLVAEVASKTNDIAGDGTTTATVLTQAIVGEGLKNVTAGANPVGIRTGIEKATAAAVAKLHEMSHTVNTKDEIAQIASISAANEEVGELIAEAMDKVGNDGVITIEESKGIETTLDVVEGMQFDRGYMSQYMVTDNDKMEANLDNPYILITDKKIGNIQDILPVLQSVVEQGRALLIIADDITGEALPTLVLNKMRGTFNVVAVKAPGFGDRRKAQLEDIAILTGGTVITEDLGLNLKDVTIDQLGQASKINITKDNTTIVEGSGDKGAVASRVDTIKQQIAETTSDFDREKLQERLAKLAGGVAVINVGAATETELKERKYRIEDALNATRAAVEEGFVAGGGTALVNVIAAVSALSEEGDVQTGINTVIKALESPVRQIAENAGLEGSVIVNKLKEQKEGFGYNAATDEWVDMIAAGIVDPTKVTRSALQNAASVSALLLTTEAVVAEEPKDDAPAAMPQGGMPGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_STRP7
Sequence: MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIKQYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTGALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSFYAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVADVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLNYSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: CFD1_ASPOR
Sequence: MPLDGVKNIVLVLSGKGGVGKSSVTLQLALALTLQGKSVGILDIDLTGPSIPRLVGLEDAKITQAPGGWVPVTVHPASTNDGAQRGSLRCMSLGFLLRDRGDAVIWRGPKKTAMIRQFLSDVYWGETDYLLVDTPPGTSDEHIALAEQLLRPATTNPAAGSSTMPRLAGAVLVTTPQAVATSDVRKEVNFCVKTQIPMLGVIENMSGYTCPCCGEVTNLFSSGGGQVMAQETGVKFLGAVPVDIQFGELVEGKVVDESDDESEDGAQPEQKREQKQDEVVDERPLVERYKDCWSYSRFEGFADTLLSEIEGGVAY
What is the function of this protein?
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery.  Required for maturation of extramitochondrial Fe-S proteins.  The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
What are the official names of this protein?
Cytosolic Fe-S cluster assembly factor cfd1, Cytosolic Fe-S cluster-deficient protein 1.
What is the protein family that this protein belongs to?
Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.