PharMolix/UniProtQA huggingface dataset:
Protein: STRBP_XENLA
Sequence: MRSIRSFANDDRHVMAKHSIIYPSPEELEAVQNMVSTVESALKQVSDWIDEQKCTKIENGSPIKNESTEDSSAKDESGKVLCGVMRIGLVAKGLLIKDDMDLELVLLCKEKPSTRLLTTVAENLPLQIQKITEETFQVEQCVEESSLLIQSSKEPKLTLKVILSSPLFREEEERPGGVENVAMKDPPDLLDRQKCLNALASLRHAKWFQARANGLKSCVIVLRILRDLCNRVPTWAQLKGWPLELICEKAIGTCNRPLGAGEALRRVMECLAFGTLLPGGSGLHDPCEKEPTDALAYMTVKEREEITHSAQHALRLLAFGQIYKVLQMDPLPSNKPFQKYSWSNSDREGSCLKRPFDDGSSDEKDPNKKLKRNLSKILDSKPIDPNQPMNALMRLNQIRPGLQYKLLSQSGPVHAPVFTMSVDVDGTTHEASGPSKKTAKLYVTVKVLQAMGYPTGFDTDLECLSSDEKSDSEGKNETSFSSSSNITGNSNADNNTLEVRTQGPILTASGKNPVMELNEKRRGLKYELISESGGSHDKRFIMEVEVDAQKFKGAGPNKKVAKASAALAALEKLFSGPNAVNNKKKKIIPQTKGVVSTAVSAAVQAARGRGRVAMARGAFVGATAAAAPGYIAPGMRREEMHPEIFNGYAAPYAYSAATPAYGIPKRMVLLPVMKFPAYPVPHYSFF
What is the function of this protein?
May be involved in spermatogenesis and sperm function.  Binds to double-stranded DNA and RNA (By similarity).
What are the official names of this protein?
Spermatid perinuclear RNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_CAMHC
Sequence: MEIPHIPVLRNEVVDIFKDLQGLLIDCTLGFAGHSSAILSANENIRIFACDKDDEALDFSKKRVEIFKNRIKIFKSGFSNFLPFLETNEILNLSNVVGILADIGVSSLQIDNNDRGFSLKSDALDMRMDKNASLDAKFVVNHYSRSDLERIFYEFAELTNAKQIAAKIANYRADKEITSAKELATIIGTSNFKNRSISTATLAFQAIRIEVNKELDELNKLLDSIENSAIQNAKIAIITFHSLEDKIVKNRFKKWAQSCICPPFFERCECGNNHAIGKILTKKPITASADELKQNSRAKSAKLRVFEIKR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_DESVM
Sequence: MDMDSILLDAEERMEKALGSLDREFAKLRTGRASTSLVDNIKVDYYGTPTPISQLASVSVPDSRTLTIQPWDRSAFQLVEKAIMKSDLGLNPVNDGKIIRISIPPLTEERRKDLVKVARKYTEEAKVAVRNVRRDANDALKKLEKGKEISEDDVRKSTDDVQKLTDRFVAKSDEKCTAKEKEIMEL
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGLA_ASPCL
Sequence: MFFQTGLLLSLSLWTKVAYAAFGITTSSSSYVIDAGSANPLKFTVSRSSCDITSINYSGTELQYASKGSHISSGLGRATVSATQDGDYIKVTCATSTLTHYMVVHHGDSTIHMATHITAEPSIGELRFIARLKSDVLPNEEPFGDVSTTAGGTAIEGSDVFLVNGKTRSKFYSSQRFIDDQRHCISGSAHRVCMILNQYESSSGGPFHRDIDANNGGGFNALYWYMNSGHVQTEPYRMGLHGPYSMVFSRSGMPGTNIDTSFFANLNIKGYVPASGRGTVTGKASGADSRMKWVVHWHNTAAQYWTYTASDGSFTSPAMKPGTYTMVYYQGEYKVAETSVTVRAGSKITKNISGSVKTGKTIFKIGEWDGQPTGFRNADKQLRMHPSDSRMAAWGPLTYTVGRSAPSDFPMAVFKSVNNPVTIKFTASAAQTAAATLRIGTTLSFAGGRPQAKINSYTAAAPPAPKNLDSRGVTRGAYRGLGEVYDVAIPAGTIVAGVNTITISVVSGNSGEKFLSPNFVFDCVELFQ
What is the function of this protein?
Pectinolytic enzymes consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Degrades the rhamnogalacturonan I (RG-I) backbone of pectin.  Active against linseed rhamnogalacturonan (By similarity).
What are the official names of this protein?
Probable rhamnogalacturonate lyase A.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 4 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TATB_VIBPA
Sequence: MFDIGFWELVLISVVGLVVLGPERLPHAIRSVSRFIGAAKNMANSVKDELSHELKVQELQENLRKAEQMGMEDLSPELKSSVEELKKAAQSVNRPYADKAQSETETAKAEPVTESAEKVEEIKVSAADKKAE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYSC_SYNP2
Sequence: MEHRGVTVWFTGLSGAGKTTISHALAERLKAAGCKLEILDGDIVRTNLTKGLGFSKEDRDENIRRIGFVSHLLTRNGVIVFVSAISPYREIREEVRQRIGDFVEIFVNAPLEECERRDVKGLYQRARAGEIKGFTGIDDPYEAPTNPEVECRTDLEELEESIEKVMKKLTELGYITP
What is the function of this protein?
Catalyzes the synthesis of activated sulfate.
What are the official names of this protein?
Adenylyl-sulfate kinase, APS kinase, ATP adenosine-5'-phosphosulfate 3'-phosphotransferase, Adenosine-5'-phosphosulfate kinase.
What is the protein family that this protein belongs to?
Belongs to the APS kinase family.
Protein: ATP23_KLULA
Sequence: MSVPPPPKEDLIKPNPPKSESAVSGFNWWRRTFQYKTGLGLTPEEETQYENDYKFVLQRKQCSKCYEYRDWLLNYSPTVIFMTQQIAKLNNKNTNADVFKFDESKIICDVCPDWKSGGFHPDLGILICQNRIKDKWHLEDTLAHELVHYFDNLKWEVDWLNLRHHACSEIRASSLSGECRFFQEFARRGFNTGFKVDRGHQACVKRRAAISVSGNPNCRDKEHAERVVDEVWDSCFNDTRPFDEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease ATP23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: CSN2_SCHPO
Sequence: MSNDFMLEDDENYDFEFEDDDDDMIEPYVDVENCYYNSKSLKEENPESALTSFYSIVEKCEGEQNEWAFKALKQITKINFQLKKYDDMLQSYQRLLGYTNWLSITKNYSEKSIYNIVEYASSCENTEFLEKFYDVTTKALQNLNNERLMLKVLMHVARFLLTQKNYHKFKYLLRQMHELLSDENNSVADQNRGTHLLELYSLEIQMYSDIEDNKRLKELYQSSLRVKTAIPHPRIMGIIRECGGKMHMQENQWSEAQTNFFESFKSYDEAGSSDRIRVLKYLVLANMLSESEINPFDSPETQPYKDNPHIIAMTKLVEAYQIRDITAVERILQTYQHDILDDDFIRQYVDKILYSIRSQVLIELVKPYTSVKLSLLAKKLGVSISIIEQALVGLIIDERVNGKIDMVNEVFTISQPKNTIHNQLVEDVQKLWNTATK
What is the function of this protein?
Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes (By similarity).  Required, indirectly, for activation of ribonucleotide reductase through the degradation of the protein spd1, thereby supplying deoxyribonucleotides for DNA replication and repair.
What are the official names of this protein?
COP9 signalosome complex subunit 2, CSN complex subunit 2, SGN2.
What is the protein family that this protein belongs to?
Belongs to the CSN2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DER_RHILO
Sequence: MTFKVAIIGRPNVGKSTLFNRLVGRKLALVDDTPGVTRDRRVHAAKLYDLHFDVIDTAGFEDAGASTLPGRMRAQTEIAIHEADLIFFTIDAKSGLLPDDRTFAEIVRKSGKPVVLVANKAEAKGAQGGMLEAWELGLGEPIPVSAEHGQGMPDLRDAVIAALGEARAFGEEEEGEDDEIAATEVLIGEDIADPDAEDAHTYDNTKPMRIAVVGRPNAGKSTLINALIGEERLLTGPEAGITRDSISVDWDWHGRRLKLFDTAGMRRKARIHEKLEVMSVQDGLRAIRFAEIVIIVLDATIPFEKQDLQIADLIIREGRAPVIAFNKWDLIDHPQELLAELREKTERLLPQVRGIQAVPVSAETGRGLDKLMDAVLRTHKVWNSRVSTGKLNRWLEAILAHHPPPAVAGRRLKVKYVTQAKTRPPGFVVQCSRPDAMPQSYVRYLSNSLREAFDMPGVPIRIALRTSDNPFAGRAKKRG
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: LPXA_BURCJ
Sequence: MTRIHPTAIVEPGAQIDESVEIGPYAIVGPHVTIGARTTIGSHSVIEGHTTLGEDNRIGHYASVGGRPQDMKYKDEPTKLVIGNRNTIREFTTIHTGTVQDVGVTTLGDDNWIMAYVHIGHDCRVGNNVILSSNAQMAGHVEIGDFAIIGGMSGVHQFVRIGAHSMLGGASALVQDIPPFVIAAGNKAEPHGINVEGLRRRGFSADAISALRSAYRVLYKNGLSLEEAKVQLRELAGAGGDGDAPVKALVEFIDASQRGIIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_PROMH
Sequence: MAIQRTFSIIKPNAVKKNVIGAIYNRFESAGFSIVAAKMLHLTREQAEGFYEEHKGRPFFDGLVEFMTSGPIMVQVLEGENAIQRHRDLMGATNPDNALAGTLRADYADSFTENAVHGSDSEASAAREIAYFFTENEICPR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_CAUVN
Sequence: MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGIALTAEMIQVFLDKRRPGNGKFVTQRQEPDAVRILSGVFEDARSNGQRTTGTPISLMIENTDQRSKDYSEIAQAFRPGHADYAYFAKYGVRDYRGGGRSSARETAARVAAGAVARLIIPGVTVRAALVQIGPHKIDRSNWDWAQTEQNPYWSPDAAIVPVWEEHLEKIRKAGSSTGAVVEVEATGVPAGWGAPLYAKLDAELAAALMSINAAKGVEIGDGFDSAALTGEDNADTMRMGDDGQPVFQSNHAGGILGGISSGQPIVARVAFKPTSSILIPRETVNEAGEEIELRTKGRHDPCVGIRGVPVVEAMTACVLADAFLRHRGQTGREHFPLGASA
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: ZRAS_KLEOX
Sequence: MNVMRLSKDSVAVGLSWLLTGLILLLVCLFSALIVRDYGRENEAARQTIQEKGSVLIRALESGTRVGMGMRMHHSQLQTLLEEMAWQPGVLWFAVTDENGKIIAHSDPRRVGESLYPASTLRELNIGSEERWRRLEQPEPALEIYRQFRPLNGGGHHMRMMMRRESADLRNQAPQVIFIAFDTRELDADHARGLRNMVIMLCAAGVVMAATVLAQFWFRRYQRSRKQLQEATARKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERTPADGEAHQLALVMAREADRLNRVVSELLELVRPAHLKYQSVDLNEVITHSLQLVSQDAASRAISLTFTAQPALCRIQADPDRLKQVLLNLYLNAVHAIGREGVITVAVRECGDGRVKVSVADSGKGMTAEQLQAIFTPYFSTKADGTGLGLAVVQNIVEQHGGTIDAESAPGKGALFTFYLPVNGQQKDEQG
What is the function of this protein?
Member of the two-component regulatory system ZraS/ZraR.  May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium (By similarity).
What are the official names of this protein?
Sensor protein ZraS.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RUTD_CAUVN
Sequence: MRRMTIGTVDGLHYELHGGPIAGREVVLLSSGLGGSGAFWAPQMQALTQRWPVVTYDHRGTGRSVRELPPRYTLAHMADDMVKVMDALGLAKAHVVGHAAGGNAGLQLALDHPDRLAKLVVVNGWSRPDPHIRRCFDTRLHLLNDTGPEAYVHAQPIFLYPADWISRNHTRLMAEEAHHVAAFPPREVMLARINALLAFDIDARLEDITHRVLISASADDMLVPMSCSQRLAGRLPNADFQQVAWGGHGFTVTDPETFNEALVSFLEGA
What is the function of this protein?
Involved in pyrimidine catabolism.  May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously.
What are the official names of this protein?
Putative carbamate hydrolase RutD, Aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Hydrolase RutD family.
Protein: HUTI_RHIME
Sequence: MDGNENPNPARTSLWRNARLATLREELGPLGIIEDGVIAVRGERIVYAGPEAGLPSELARADQVFDCEGRWVTPALIDCHTHIVHGGNRAREFQLRLEGATYEEIARAGGGIASTVEATNALSVEALVEAALPRLDTLLAEGVSTVEVKSGYGLNVEAELKMLRAARRLESLRPVRIVTSYLAAHATPPEFRGRNGDYIAEVVLPGLTAAHAEGLADAVDGFCEGIAFSPAEIASVFGRAKSLGLPVKLHAEQLSDLGGAKLAASYGALSADHLEYLDAAGAAAMAKAGTVAVLLPGAFYTLREKQLPPVEALREAGTRIAIATDCNPGTSPLTSLLLTLNMSATLFRLTLEECLAGVTREAARALGILGETGTIEAGKSADLAIWNIDQPAELIYRIGFNPLRERIFKGERILR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BACVZ
Sequence: MVTLDGSSLTTADAQRVLFDFEEVQASAESMERVKKSRAAVERIVQEEKTIYGITTGFGKFSDVLIQKEDAADLQLNLILSHACGVGDPFPESVSRAMLLLRANALLKGFSGVRTELIDQLLAYLNHRIHPVIPQQGSLGASGDLAPLSHLALALIGQGEVFYEGARMPTAHALEQTNLQPAVLTSKEGLALINGTQAMTAMGLIAYLEAEKLAYQSERIASLTIEGLQGIIDAFDEDIHAARGYQEQMDVAERIRYYLSDSKLTTVQGELRVQDAYSIRCIPQVHGASWQTLAYVKEKLEIEMNAATDNPLIFEDGAKIISGGNFHGQPIAFAMDFLKVAAAELANISERRIERLVNPQLNDLPPFLSPQPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHAYQIIANTRRVLAVEAICALQAVEYRGEEHCASYTKQLYHEMRNIVPSIQEDRVFSYDIEHLSDWLKKESFLPNEHHQKLMTNEGGLTR
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPO4_HALHL
Sequence: MTWRKIIHIDMDAFYASVEQRDDPSLRGQPVVVGGSPEGRGVVAAASYEARAFGIRSAQPAAWARRRCPEAIFLRPRFDRYRAISRQIHGIFADFATTIEPLSLDEAYLDVTGSQRFRGSATHMAQAIRRRIREETGLTASAGVSYNKLLAKLASDEGKPDGLYVVPPEDGPAYVAAQPIRRLHGVGPATAARLERLGIRQVGDLLDWELADLHVFLGNRAGTLHDAARGIDHRPVRPRRSRKSIGAERTFGDDTRDLGEIHQRLAPLITKVATRLEHHELVARTVTLKLRYADFESITRRVSPPGPVAQAADIEALIPALLAETEAGSRPVRLLGVSLSGLQPKQREQDLFSALT
What is the function of this protein?
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis.  Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends.  These misaligned primers can be extended by PolIV.  Exhibits no 3'-5' exonuclease (proofreading) activity.  May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
What are the official names of this protein?
DNA polymerase IV, Pol IV.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-Y family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YFCN_ECOSM
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVDEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: SECE_PSEAE
Sequence: MNAKAEAKESRFDLLKWLLVAVLVVVAVVGNQYFSAQPILYRVLGILVLAVIAAFLALQTAKGQAFFSLAKEARVEIRKVVWPSRQETTQTTLIVVAVVLVMALLLWGLDSLLGWLVSMIVG
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: VWCE_MOUSE
Sequence: MWARLLLHVAYILIPLLGSSARGYTGRKAPGHYSAERRRLGPHVCLSGFGSGCCPGWAPSMGSGHCTLPLCSFGCGSGICIAPNVCSCQDGEQGATCPEAHGSCGEYGCDLTCNHGGCQEVARVCPVGFLMTETAVGIRCADIDECLSSSCEGHCVNTEGGFVCECGPGMQLSADRHSCQDTDECLGTPCQQRCKNSIGSYKCSCRAGFHLHGNRHSCIDVNECRRPQERRVCHHTCHNTVGSFLCTCRPGFRLRSDRVSCEAFPKAVLAPSAILQPRQHPAKMSLLLPEAGRPALSPGHSPPPGAPGYPTGVRTISQPSTTQVLPTFFPTQLISTPVPSSSPLGTLGPPSLLQGAVGTPSSPRGPESPKLGAGSSSCWHLGATYESGSRWNQPGCSQCLCQDGEVTCGGVRCDATCSHPVPPRDGGCCPSCTGCFHSGAIRAEGDVFSPPEENCTVCVCLAGNVSCISPECPPGPCKASPQSDCCTCVPGRCYFHGRWYTDGAVFSGGGDDCTTCVCQNGEVECSFTPCPELECPREEWLLGPGQCCFTCREPTPTTGCSLDDNGVEFPIGQIWSPGDPCELCVCQADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAGCTYTGRIFYNNETFPSVLDPCLSCICLLGSVACSPVDCPITCTYPFHPDGECCPVCHDCNFEGRKVVNGQVFTLDDEPCTRCICQLGEVSCETVPCRPICTDPSCPDSVFPLEEKQQPSPHGELAKAARNARGDTEVPVNCSSCPGPPSASPTRPMVHLLQRLLRTNLSNIQSASPSPPIAQTSSSPLLEPEGISLGKPRASQPPEPSAGSPVSPRLSTLPPAIPGTPLSPVTPESSSSTFGTQTAFQWLLSATPLTEAETPSMTNADLSETLTTSSSSQRLSAALPDTPNPVPQQSTIDTPKKENSTI
What is the function of this protein?
May be a regulatory element in the beta-catenin signaling pathway and a target for chemoprevention of hapatocellular carcinoma.
What are the official names of this protein?
von Willebrand factor C and EGF domain-containing protein.
What are the subcellular locations of this protein?
Secreted.
Protein: ACKA_MYCGE
Sequence: MQSHKILVVNAGSSSIKFQLFNDKKQVLAKGLCERIFIDGFFKLEFNQKKIEEKVQFNDHNLAVKHFLNALKKNKIITELSEIGLIGHRVVQGANYFTDAVLVDTHSLAKIKEFIKLAPLHNKPEADVIEIFLKEIKTAKNVAVFDTTFHTTIPRENYLYAVPENWEKNNLVRRYGFHGTSYKYINEFLEKKFNKKPLNLIVCHLGNGASVCAIKQGKSLNTSMGFTPLEGLIMGTRSGDIDPAIVSYIAEQQKLSCNDVVNELNKKSGMFAITGSSDMRDIFDKPEINDIAIKMYVNRVADYIAKYLNQLSGEIDSLVFTGGVGENASYCVQLIIEKVASLGFKTNSNLFGNYQDSSLISTNESKYQIFRVRTNEELMIVEDALRVSTNIKK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIG_ECO8A
Sequence: MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPLTNTFKLGPGVDVNYMLHTQNK
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-octaprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone-8 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: MTNB_CANTT
Sequence: MSAPCHCKHAEELTDTFSSSSLSYTNGKLSVLSPELQAEFQDPNHPANLICELCRLFYDNNWVTGTGGGISIRDVDGPNPNLVYIAPSGVQKERIQPWEMFLVELPDERIIRTPNDIPKELTKSYKYKPSACTPLFISCYTMRDAGACIHTHSQHAVMMTLFLENEKEFSISHIEQIKALPKLKYNEETKKIEKIGSMEYYDKLVIPIIENTPHEEDLTDSLQEAIKNYPGASAVLVRRHGIYVWGETVWKAKVYNEAIDYLLELAVKMKLAGIPLVKE
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYP1_RHOJR
Sequence: MITRLSHLFLRTLRDDPADAEVPSHKLLVRAGYVRRIAPGVYSWLPLGLRVLREVERVVREEMNGIGAQEISLPALLPREPYEASNRWTEYGDGLFRLKDRKGGDYLLGPTHEELFALTVKGEYNSYKDFPVTLYQVQTKYRDEERPRAGILRGREFVMKDSYSFDLTDEGLTASYRAHRDAYERIFSRLGVKYVIVSATSGAMGGSASEEFLAESEIGEDTYVRCLESGYAANVEAVKTLAPEAVPFDGLPAAKVHDTPDTPTIATLVDWANGADLGWTVTAADTLKNILVKTRQPGGKWELLGIGVPGDREVDDKRLGASLEPAEFELLTEADFAANPFLVKGYIGPKALQANGVRYLVDPRIVDGTSWITGADEPGKHVVGLVAGRDFTPDGTIEAAEVRDGDPSPDGAGALVAARGIEIGHVFQLGRKYTDVFSVDVLGENGKPVRPTMGSYGVGVSRLVAVIAEQHHDEKGLRWPAEVSPADVHVVIANKDETAREGAEGLAAELDKAGLEVILDDRKASPGVKFKDSELLGVPLVVVVGRGWGEGKVEVRDRFTGESREVAAESALSEIVKAVRG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase 1, Prolyl-tRNA synthetase 1, ProRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XYLT_CAEEL
Sequence: MLFNGTTKYRDYAIVISLFFLLNVYLLYNTAQHTQVGNSKHISSDSGEKTSNPLPSCEITDDLAKSAISRAITPSCKAKLQLEACQLKNGTFTINFPENQCPNHDSRLIDQRIGCFLDKKEARVLTEFEYKLPKSNGKATCRKHCYKAGFLYFGLEFGHECFCGNDVSNATAVDDVECRAYKCPGNENSEEFCGGFNAVEIFRTGFRSKVNHRKPTYLPPSSDSIKNPVKILFLLQLNGRNERQVKRFLKSIYLPHHYYYIHVDARQNYMFSEMQKVADFLDNIHITERRFSTIWGGASLLQMFLQVIRDSMKIEKFKDWDYIINFSESDFPILPISDFERLITVNNGKSFLASHGYNTGKFIQKQGFEYVFSECDNRMFRIGKREFPQNLRIDGGSDWVGIHRNLAEFSISDEELPRKLRKTYESILLPLESFYHTLAFNSEFCDDLLMSNLRLTNWYRKQGCRCASLKPIVDWCGCSPLVFREETMKKFELQKAISKPTYFARKFDSMVDIDSIEAAEMQSISPEKLQLNHPTYHFAFANIFKTGIDEQKLHFESLANFALKSTETRAKFRKVLRIDALRAHHNALIEIVMKIETTDGATFEFLIHRLSHVNLTENEEKLVEHGYLLRAVSFGTKFEWKEELCREYMGFVTDNDTLHTRLQWHPTEHVKKVGDKTSPEMIFKYRKGDELIEQTVVKPYDSVFGGQFDSWNVGKKLSNLTTCSNFFVDIISPSSPDDAPPLATLHFPVYTDQNAHCHVDYLRQFFKIADFCTSGDACKEKIWSTSYPDPKSDIFVGYDEDTQTLI
What is the function of this protein?
Catalyzes the first step in biosynthesis of glycosaminoglycan.  Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein.  Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.  Required for vulval morphogenesis and zygotic cytokinesis, suggesting that glycosaminoglycans play a central role in vulval morphogenesis.
What are the official names of this protein?
Xylosyltransferase sqv-6, Peptide O-xylosyltransferase, Squashed vulva protein 6.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 14 family. XylT subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: TPST2_MACFA
Sequence: MRLSVRRVLLAAGCALVLVLAVQLGQQVLECRAVLAGLRSPRGAMRPEQEELVMVGTNHVEYRYGKAMPLIFVGGVPRSGTTLMRAMLDAHPEVRCGEETRIIPRVLAMRQAWSKSGREKLRLDEAGVTDEVLDAAMQAFILEVIAKHGEPARVLCNKDPFTLKSSVYLSRLFPNSKFLLMVRDGRASVHSMITRKVTIAGFDLSSYRDCLTKWNKAIEVMYAQCMEVGKDKCLPVYYEQLVLHPRRSLKLILDFLGIAWSDAVLHHEDLIGKPGGVSLSKIERSTDQVIKPVNLEALSKWTGHIPGDVVRDMAQIAPMLAQLGYDPYANPPNYGNPDPIVVNNTQRVLKGDYKTPANLKGYFQVNQNSTSSHLGSS
What is the function of this protein?
Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
What are the official names of this protein?
Protein-tyrosine sulfotransferase 2, Tyrosylprotein sulfotransferase 2, TPST-2.
What is the protein family that this protein belongs to?
Belongs to the protein sulfotransferase family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: CLPS_SALTI
Sequence: MGKTNDWLDFDQLVEDSVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.