PharMolix/UniProtQA huggingface dataset:
Protein: CLPP_RICAH
Sequence: MSYVPIVIEQTSRGERAYDIYSRLLKERIIFVCSTVEDHMANLIVAQLLFLEAENPKKDVYMYINSPGGVVTAGLAIYDTMQYIKPKVATLCIGQACSMGSLLLCGGTQGMRYSLPHSRIMIHQPSGGYKGQATDIEIHAQETLKIKRLLNELYSKHTGQELKHIEKSMERDNFMSPEEAKKFGIIDNIISSRDVMTMSAK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIA4_MYCTO
Sequence: MSGGSSRRYPPELRERAVRMVAEIRGQHDSEWAAISEVARLLGVGCAETVRKWVRQAQVDAGARPGTTTEESAELKRLRRDNAELRRANAILKTASAFFAAELDRPAR
What are the official names of this protein?
Insertion element IS6110 uncharacterized 12.0 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the transposase 8 family.
Protein: RS17_SYNAS
Sequence: MSERGFNRTIKGVVVSNKMDKTIVIRAERLVKHPVFHKYTRKHVKYMVHDEKNECKVGDTVIVMESRPLSRLKRWRMLRIVAKAE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RBL_BRAOL
Sequence: MSPQTETKASVGFKAGVKEYKLNYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGEETQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALAALRLEDLRIPPAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKSQAETGEIKGHYLNATAGTCEEMMKRAIFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHVHAGTVVGKLEGDRESTLGFVDLLRDDYVEKDRSRGIFFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAVEGNEIIREACKWSPELAAACEVWKEITFNFPTIDKLDGQD
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATPA_THEP1
Sequence: MRINPGEITKVLEEKIKSFEEKIDLEDTGKVIQVGDGIARAYGLNKVMVSELVEFVETGVKGVAFNLEEDNVGIIILGEYKDIKEGHTVRRLKRIIEVPVGEELLGRVVNPLGEPLDGKGPINAKNFRPIEIKAPGVIYRKPVDTPLQTGIKAIDSMIPIGRGQRELIIGDRQTGKTAIAIDTIINQKGQGVYCIYVAIGQKKSAIARIIDKLRQYGAMEYTTVVVASASDPASLQYIAPYAGCAMGEYFAYSGRDALVVYDDLSKHAVAYRQLSLLMRRPPGREAYPGDIFYLHSRLLERAVRLNDKLGGGSLTALPIVETQANDISAYIPTNVISITDGQIYLEPGLFYAGQRPAINVGLSVSRVGGSAQIKAMKQVAGMLRIDLAQYRELETFAQFATELDPATRAQIIRGQRLMELLKQEQYSPMPVEEQVVVLFAGVRGYLDDLPVEEVRRFEKEFLRFMHEKHQDILDDIKTKKELTSETEEKLKKAIEEFKTTFRV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS10_PSELT
Sequence: MPGQKIRIKLKAYDHEVLDESAKKIVEVAKSTNAKISGPIPLPTERALYVVLRSPHKHKDSREQFEKRVHKRLIDIIEPSPKTIDALMKINLPAGVDVEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RL31_ACIBY
Sequence: MRADIHPKYEKLVATCSCGNVIETRSALGKETIYLDVCSACHPFYTGKQKNVDTGGRIDKFKQRFAGMSRSIKR
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: UXAB_SHIF8
Sequence: MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGALDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFALAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKYHWEQDLTQVPGLVEQVANDLDAILEKGMREAVRPLC
What are the official names of this protein?
Altronate oxidoreductase, Tagaturonate dehydrogenase, Tagaturonate reductase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family. UxaB subfamily.
Protein: MODC_RHORT
Sequence: MLDIDVLRQQGALRLSIAFRAGKGVTALFGRSGAGKTSVISMVAGLSRPDGGRIVVDDRVLFDGAKGIDLAPEKRRVGYVFQEGRLFPHLTVRQNLAFGMNRVPAAERYVGEDDVVDLLGISALLDRRPAKLSGGEKQRVAIGRALLASPRILLMDEPLASLDAQRKDEVLPFIARLPRRFSIPILYVSHAMDEVLRLADTLVLIAEGQVAASGPLEEVLARPDIPDFAAQRDAGAVVAAKVAGRDIPFGATLLDTPAGLLRTRPIDLPLGTKVRVRIAAADISLALERPRMVSVQNILAATILAIGEPEDGRLSVDLDAGPPGGPPCRLWASITARARHDLGLVPGLRVHALIKAMSLLRDELVEHSPH
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RBM24_DANRE
Sequence: MHTTQKDTTYTKIFVGGLPYHTTDSSLRKYFEVFGEIEEAVVITDRQTGKSRGYGFVTMADRSAADRACKDPNPIIDGRKANVNLAYLGAKPRVMQPGFTFGVPQIHPAFIQRPYGIPTHYVYPQAFMQPSVVIPHIQPTATSATASSPYIDYTGAAYAQYASAATAAAAAAYEQYPYAASPAATGYVAAAGYGYAMQQPLATAAPGSAAAAAAAFGQYQPQQLQAERMQ
What is the function of this protein?
Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation.  Plays a major role in pre-mRNA alternative splicing regulation.  Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation.  Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing.  Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes.  Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound.  Involved in myogenic differentiation by regulating myog levels.  Binds to a huge amount of mRNAs (By similarity).  Required for embryonic heart development, sarcomer and M-band formation in striated muscles (PubMed:22345307).
What are the official names of this protein?
RNA-binding protein 24, RNA-binding motif protein 24, RNA-binding protein SEB-4.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: RDRP_I81A4
Sequence: MDVNPTLLFLKVPAQNAISTTFPYTGDPPYSHGTGTGYTMDTVNRTHQYSERGKWTINTETGAPQLNPIDGPLPEDNEPTGYAQTDCVLEAMAFLEKSHPGIFENSCLETMEVIQQTRVDKLTQGRQTFDWTLNRNQPAATALANTIEVFRLNGLTTSESGRLIDFLKDVMESMDKEEMEIVTHFQRKRRVRDNMTKKMVTQRTIGKKKQKLNKRGYLIRALTLNTMTKDAERGKLKRRAIATPGMQIRGFVYFVETLARSICEKLEQSGLPVGGNEKKAKLANVVRKMMTNSQDTELSFTITGDNTKWNENQNPRMFLAMITYITRNQPEWFRNVLSVAPIMFSNKMARLGKGYMFESKNMKLRTQIPAEMLSGIDLRYFNDSTRKKIEKIRPLLIEGAASLSPGMMMGMFNMLSTVLGVSILNLGQKEYTKTAYWWDGLQSSDDFALIVNAPNHEGIQAGVDRFYRTCKLLGINMSKKKSYINRTGTFEFTSFFYRYGFVANFSMELPSFGVSGINESADMSIGVTVIKNNMINNDLGPATAQMALQLFIKDYRYTYRCHRGDTQIQTRRSFEIKKLWDQTRSKAGLLVSDGGPNLYNIRNLHIPEVCLKWELMDKDYQGRLCNPLNPFVSHKEIESVNNAVVMPSHGPAKTMEYDAVATTHSWVPKRNRSILNTSQRGILEDEQMYQKCCNLFEKFFPSSSYRRPVGISSMVEAMVSRARIDARIDFESGRIKKEDFAEIMKICSTIEDLRRQK
What is the function of this protein?
RNA-dependent RNA polymerase which is responsible for replication and transcription of virus RNA segments.  The transcription of viral mRNAs occurs by a unique mechanism called cap-snatching.  5' methylated caps of cellular mRNAs are cleaved after 10-13 nucleotides by PA.  In turn, these short capped RNAs are used as primers by PB1 for transcription of viral mRNAs.  During virus replication, PB1 initiates RNA synthesis and copy vRNA into complementary RNA (cRNA) which in turn serves as a template for the production of more vRNAs.
What are the official names of this protein?
RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 1, PB1, RNA-directed RNA polymerase subunit P1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses polymerase PB1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm.
Protein: SGBH_HAEIN
Sequence: MGKPLLQIALDAQYLETALVDVKQIEHNIDIIEVGTILACSEGMRAVRILRALYPNQILVCDLKTTDAGATLAKMAFEAGADWLTVSAAAHPATKAACQKVAEEFNKIQPNLGVPKEIQIELYGNWNFDEVKNWLQLGIKQAIYHRSRDAELSGLSWSNQDIENIEKLDSLGIELSITGGITPDDLHLFKNTKNLKAFIAGRALVGKSGREIAEQLKQKIGQFWI
What is the function of this protein?
Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P.
What are the official names of this protein?
Probable 3-keto-L-gulonate-6-phosphate decarboxylase, KGPDC, 3-dehydro-L-gulonate-6-phosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the HPS/KGPDC family. KGPDC subfamily.
Protein: EMBR_MYCBO
Sequence: MAGSATVEKRLDFGLLGPLQMTIDGTPVPSGTPKQRAVLAMLVINRNRPVGVDALITALWEEWPPSGARASIHSYVSNLRKLLGGAGIDPRVVLAAAPPGYRLSIPDNTCDLGRFVAEKTAGVHAAAAGRFEQASRHLSAALREWRGPVLDDLRDFQFVEPFATALVEDKVLAHTAKAEAEIACGRASAVIAELEALTFEHPYREPLWTQLITAYYLSDRQSDALGAYRRVKTTLADDLGIDPGPTLRALNERILRQQPLDAKKSAKTTAAGTVTVLDQRTMASGQQAVAYLHDIASGRGYPLQAAATRIGRLHDNDIVLDSANVSRHHAVIVDTGTNYVINDLRSSNGVHVQHERIRSAVTLNDGDHIRICDHEFTFQISAGTHGGT
What is the function of this protein?
Positively regulates the transcription of the embCAB operon.  Exhibits ATPase and GTPase activities (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein EmbR.
What is the protein family that this protein belongs to?
Belongs to the AfsR/DnrI/RedD regulatory family.
Protein: RL10_XYLFA
Sequence: MALNIFQKQEVVEELAGVATKAHSLIVAEYAGITVSQMTAMRKQARESGVYLKVVKNKLAARALGDTEYAVIKEKLIGPLLYAFSLEDPGAAGRLIKEFSKKHDKLKSKTVSLGGVLYPAGHVDVLASLPTRLQALAMLARVLSEPVTLFARAIKAVADDKSETVAVSAPEASQA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RS14Z_THEP3
Sequence: MARKALIVKQQKPQKYKTREYNRCKICGRPHAYLRKFGMCRICFRKYAHQGMIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PSPA_DEIRA
Sequence: MSIFDRLSRLLRANVNDMISKAEDPAKIIDQALRDMRSAYADARNEVAGAMAQAAKLEREAGTNSKLAAEYEKKAEEALRGGSEDLAREALRRAQNHKDLAKGFDEQRTVQQSTVDQLKTQLRALEAKIDEMESKKTLLAARQKTAQAGETLDRVSGFSKAGGAMDAFNEMEQKVAGMEDRNKAMGELRNDQDFDAQLKDLGRDKDVDDALAALKAKVQSSNQ
What are the official names of this protein?
Phage shock protein A homolog.
What is the protein family that this protein belongs to?
Belongs to the PspA/IM30 family.
Protein: RL25_CHLPN
Sequence: MELVVTSRETGKKSFLKKIRQQGGIPAVVYSAGKSLANITVDALVFKKFLSNLESGALSSTVFSLSYEGRIIKALVKDIQYQITTYDVIHLDFEELVEDRPVKLNIPIRCINAVDCIGVKLGGSLRQVIRAVRVVCKPKDIVPFLELDVRSVGLSQTRKLSDIKIPAGIETITPLKEVAITVSRR
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: 4F2_HUMAN
Sequence: MELQPPEASIAVVSIPRQLPGSHSEAGVQGLSAGDDSELGSHCVAQTGLELLASGDPLPSASQNAEMIETGSDCVTQAGLQLLASSDPPALASKNAEVTGTMSQDTEVDMKEVELNELEPEKQPMNAASGAAMSLAGAEKNGLVKIKVAEDEAEAAAAAKFTGLSKEELLKVAGSPGWVRTRWALLLLFWLGWLGMLAGAVVIIVRAPRCRELPAQKWWHTGALYRIGDLQAFQGHGAGNLAGLKGRLDYLSSLKVKGLVLGPIHKNQKDDVAQTDLLQIDPNFGSKEDFDSLLQSAKKKSIRVILDLTPNYRGENSWFSTQVDTVATKVKDALEFWLQAGVDGFQVRDIENLKDASSFLAEWQNITKGFSEDRLLIAGTNSSDLQQILSLLESNKDLLLTSSYLSDSGSTGEHTKSLVTQYLNATGNRWCSWSLSQARLLTSFLPAQLLRLYQLMLFTLPGTPVFSYGDEIGLDAAALPGQPMEAPVMLWDESSFPDIPGAVSANMTVKGQSEDPGSLLSLFRRLSDQRSKERSLLHGDFHAFSAGPGLFSYIRHWDQNERFLVVLNFGDVGLSAGLQASDLPASASLPAKADLLLSTQPGREEGSPLELERLKLEPHEGLLLRFPYAA
What is the function of this protein?
(Microbial infection) In case of hepatitis C virus/HCV infection, the complex formed by SLC3A2 and SLC7A5/LAT1 plays a role in HCV propagation by facilitating viral entry into host cell and increasing L-leucine uptake-mediated mTORC1 signaling activation, thereby contributing to HCV-mediated pathogenesis.
What are the official names of this protein?
4F2 cell-surface antigen heavy chain, 4F2hc, 4F2 heavy chain antigen, Lymphocyte activation antigen 4F2 large subunit, Solute carrier family 3 member 2.
What is the protein family that this protein belongs to?
Belongs to the SLC3A transporter family.
What are the subcellular locations of this protein?
Apical cell membrane. Cell membrane; Single-pass type II membrane protein. Cell junction. Lysosome membrane. Melanosome. Note=Localized at the plasma membrane when associated with SLC7A5/LAT1 or SLC7A8/LAT2 (PubMed:9751058, PubMed:11311135). Localized to the apical membrane of placental syncytiotrophoblastic cells (PubMed:11742812). Recruited to lysosomes by LAPTM4B (PubMed:25998567). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Located selectively at cell-cell adhesion sites (By similarity). Colocalized with SLC7A8/LAT2 at the basolateral membrane of kidney proximal tubules and small intestine epithelia. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells (By similarity).
Protein: REV_HV1W2
Sequence: PPPNPEGTRQARRNRRRRWRERQRQIRSIGAWILSTYLGRSAEPVPLQLPPLERLTLDCEEDCGTSGTQGVGSPQVLVESPAVLEQGTKE
What is the function of this protein?
Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells.  These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts).  This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs.  Rev itself is translated from a fully spliced mRNA that readily exits the nucleus.  Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1.  KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus.  In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs.  Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface.  Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex.  Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export.  Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import.  The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm (By similarity).
What are the official names of this protein?
Protein Rev, ART/TRS, Anti-repression transactivator, Regulator of expression of viral proteins.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Note=The presence of both nuclear import and nuclear export signals leads to continuous shuttling between the nucleus and cytoplasm.
Protein: MUKB_VIBPA
Sequence: MIERGKYQSLTMVNWNGFFARTFDIDGLVTTLSGGNGAGKSTTMAAFITALIPDQTLLHFRNTTEAGSSQSSRDKGLYGKLQPGACYAALDVVNSRNQRLLFAVKLQQVAGRDKKVDIKPFVIQGLPSHVKPTDILVESVSATQARVRQINEVKDAIAEFEGVQFKAFSSIVDYHAQMFEFGVIPKKLRNSSDRSKFYRLIEASLYGGISSAITRSLRDYLLPQNGGVKKAFQDMESALRENRMTLEAIKTTQADRDLFKHLITESTNYVAADYMRHANDRRNKLEQTLSLRSELFGSRETLIEQNNLLNRVQEELELLIESESALEQDYQAASDHLQLVQNALRQQEKIERYQEDLEELSERLEEQMMVVEEAQERVMMVEEQATVAEEEVDSLKTQLADYQQALDVQQTRALQYQQAVQALEKAKQLLGDDCLTAESAQALVSELKNKESESTNALLSVKHKLDMSSAAAEQFETALKLVQSIVGQVERKDAAEQAKIVITKARESQQIAQNEQQWRAQHRDLERSLNQQRQARELVKEYQKQFHVELTDEITFEQERERHAMQIETLEMTQEELREQRSEQRRLEQDAAAEINKLEAIAPTWIAANDALEKLREQSGVDLEDRHAVMSHMQVVLEQEKELSLAKDKLAERRSQLESEIERLASPGGSNDPRLKGLADTLGGVLLSEIYDDITIDDAPYFSAMYGPARHAIVVSDLSGIEEKLVELDDCPEDLYIIEGDIDAFDDSSFDAEELEGAVCVRMNDRQMRYSRFPEIPLFGRAAREQRLELLRNEREEVVEKHAKAAFDSQKMQRLYQAFNQFVANHIQVAFEADPEQALANVREKRGQIARVLADLEAKEQQHRSQLQTSKQALSSLDKLAPNMALIEDDTLQARFDELEEKIAQLSEAKAFLNNHAKAVAELEKIASALDADPEQFDALEAEYKAADEQLQELKKQIFALSDLVERRHYFAYSDSVDLLNQSSELSEQLKAKLVQAEQMRTRSREELKQAQGQMNQYNQVLASLKSSHQAKLETVQEFKQELQEFGVNADEGAEERAIRRRDELHERLHTSRSRKSEYERTITSTELEMKGLAKRLKKVQKEYAELRTFVVAAKAGWCSVLRLARENDVERRLHKRELAYMSADELRSMSDKSLGALRLAVANNDDLRDALRLSEDNARPERKVLFYIAVYQHLRERIRQDIIRTDDPVEAIEEMEVELARLTEELTQRENRLAISSESVASIIKKTIQREQNRIRMLNQGLSNISFGQVKGVRLNVKIRESHEVLLHGLSSQQEQHKDLFESPRFTFSEAMAKLFQRVNPHIDMGQRSPQVLGEELLDYRNYLELSVEVNRGSDGWLQAESGALSTGEAIGTGQSILLMVVQSWEEESRRLRSKDIIPCRLLFLDEAARLDAKSISTLFELCDRLDMQLLIAAPENISPEKGTTYKLVRKVFKDHEHVHVVGLRGFGQTDKPKSEVQEMIEEFES
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: COX9_SCHPO
Sequence: MAVGPVTGMFKRRIVTDFSVTMILGTLGACYWWFGYHKPAARQREEFYVKLAAEKNAE
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 9, mitochondrial, Cytochrome c oxidase polypeptide VIIA.
What is the protein family that this protein belongs to?
Belongs to the fungal cytochrome c oxidase subunit 7a family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RBL_DROBR
Sequence: SVGFKAGVKDYKLTYYTPDYQTLDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEDNQYIVYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIFKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRLSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDVIEKDRSRGIYFSQFWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNPPGAAANRVALEACVQARNEGQDLAREGNEI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RNF39_RAT
Sequence: MEVPELGPGLVERLEQLATCPLCGGPFEDPVLLACEHSFCRSCLARCWGSPAAPGSEEATPSCPCCGQPCPRRSLRSNVRLAVEVRISRGLREKLAEPGARTGRRRGGRIPTMGCLDPQGEDMRKTWRRFDVPVPKSSNSEEDLPEDYPVVKNMLHRLTADLTLDPRTAHRDLLISSDYRGVSLAPPGTPVPLDSPERFDRLRAVLGAQGFASGRHCWEVETAEGACFRDSLAKDEDAGESCYAVGAAGESVTRKGLIKLCPSEAIWAVEGRGGRLWALTAPEPTLLGGARPPPQRIRVDLDWERGRVAFYDGRSLDLLFAFQAPGPLGERVFPLLCTCDPRAPLRIVPGEA
What is the function of this protein?
May play a role in prolonged long term-potentiation (LTP) maintenance.
What are the official names of this protein?
RING finger protein 39, LTP-induced RING finger protein.
What are the subcellular locations of this protein?
Cytoplasm.