PharMolix/UniProtQA huggingface dataset:
Protein: PEX10_ARATH
Sequence: MRLNGDSGPGQDEPGSSGFHGGIRRFPLAAQPEIMRAAEKDDQYASFIHEACRDAFRHLFGTRIALAYQKEMKLLGQMLYYVLTTGSGQQTLGEEYCDIIQVAGPYGLSPTPARRALFILYQTAVPYIAERISTRAATQAVTFDESDEFFGDSHIHSPRMIDLPSSSQVETSTSVVSRLNDRLMRSWHRAIQRWPVVLPVAREVLQLVLRANLMLFYFEGFYYHISKRASGVRYVFIGKQLNQRPRYQILGVFLLIQLCILAAEGLRRSNLSSITSSIQQASIGSYQTSGGRGLPVLNEEGNLITSEAEKGNWSTSDSTSTEAVGKCTLCLSTRQHPTATPCGHVFCWSCIMEWCNEKQECPLCRTPNTHSSLVCLYHSDF
What is the function of this protein?
E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling (PubMed:12883010, PubMed:14576288, PubMed:17215364, PubMed:17478547, PubMed:20679226, PubMed:23336935, PubMed:25214533).  The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity).  PEX10 also regulates PEX5 recycling by acting as a E3 ubiquitin-protein ligase (PubMed:23336935, PubMed:25214533).  When PEX5 recycling is compromised, PEX10 catalyzes polyubiquitination of PEX5 during its passage through the retrotranslocation channel, leading to its degradation (By similarity).
What are the official names of this protein?
Peroxisome biogenesis factor 10, PER10, Peroxin-10, Peroxisomal biogenesis factor 10, AtPEX10, AthPEX10, Peroxisome assembly protein 10, Pex10p.
What is the protein family that this protein belongs to?
Belongs to the pex2/pex10/pex12 family.
What are the subcellular locations of this protein?
Peroxisome. Peroxisome membrane; Peripheral membrane protein.
Protein: PMEI1_ARATH
Sequence: MAANLRNNAFLSSLMFLLLIGSSYAITSSEMSTICDKTLNPSFCLKFLNTKFASPNLQALAKTTLDSTQARATQTLKKLQSIIDGGVDPRSKLAYRSCVDEYESAIGNLEEAFEHLASGDGMGMNMKVSAALDGADTCLDDVKRLRSVDSSVVNNSKTIKNLCGIALVISNMLPRN
What is the function of this protein?
Inhibits pectin methylesterase (PME) from flowers and siliques (PubMed:14675772).  Inhibits PME from leaves (PubMed:14741367).
What are the official names of this protein?
Pectinesterase inhibitor 1, Pectin methylesterase inhibitor 1, AtPMEI1.
What is the protein family that this protein belongs to?
Belongs to the PMEI family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: GLMM_PYRFU
Sequence: MGKYFGTSGIREVVNEKLTPELALKVGLALGTYLGEGRVVVGIDTRTSSEMIKHALVSGLLATGIEVVDIGLAPTPLTGFAIKLYNADAGVTITASHNPPNYNGIKVWDRNGMAYTPDKESELERIIEEETFKRVSWMEIGEVIKADPKKEYIKNAVEQINLENSYTVVVDSGNGAGSIVSPYLQRELGNKVISLNSHPTGFFVRELEPNRKSLDMLSKVVREVGADVGIAHDGDADRIGVVDDQGNFVDYEVMLSLIAGYMIEKYGKGKVVTTVDAGFALDDYLKPRGGEVIRTKVGDVAVAYELSKHGGVFGGEPSGTWIIPQWNLTPDGIFAGALVVEMIDKLGPISELAKEVPRYVTLREKIPCPNELKQKVMRIIEKLALQNFEYKNLIDIDGIRIENEEWWILFRPSGTEPIMRITLEAHTKEKAEELMKKARGLVKEAIEKAKLS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Probable phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TOF1_COCIM
Sequence: MEIEPPQAVEVVDPEVRSYVYSLVTALGGTAGNETGRYVLGDDALGCLRDLKKWLRFYDEKLNRMDVARCLAECKLLNGDLVPIISLYGDAEQSDKHKARIMLACLELLVPLTWPVEVHGQMTFNHHRHTPYLQYSQVEYKRGILGFAPSPILRALIRVGLPSMAIPRSERSTRDEGIIRLMLYFFRNIAVISSPPNLPIDSDDDKATRSATINAFQQQDVFALLLTMCSNMGNDFTFQDVIILEILFNLVKGVDVDQLFKLNERAGTIKTDDLQDILQKEDELNREHSKNAPTRHGRFGTMIWVKRDDEKLSTVSGQDVLKGDRATFLKMDKTKKWNKPKFKREVVDPSSNNFNLKVRLTSSATKHLRTFVEEFLDSGFNPLFTHLRKAIEREADRVTESTSRQFWYAVSWFLHAERARREHQKETRQRSKGTSREIEPDSFSLVASVLNQETFVGLNRFMQHSIDFKDWQDLTAGMKCLTQILLTVQEMAISPLEEDQEIAENIQSRIFYEETTHDRVLSILRNYKDQGFWYLDACTELAHVFLRMLEQYSKQNVDMQVRSRRRARRKQAQAAVPNQNETEAGGEHDSDTEDIAEAHQTVTERSFDFKRFSVRFCTQKSVDTFVALTKYYRELDSEQLKRAHRFFYRVAFKQDMSVLLFRVDIISLLFKMIKGPEGLDPSKPPFKDWEELIRQIFKKLVRKLGERPELVVELLFSKINATVFYLEYGHEKQTMSESRPATELELKPGSASTLDEKIRIVVSALIQEDKKPLVKWLSQVLGSAASERLSWEMEAEARATSSPQEQSDRSKAPSIAVLPEDDGCRTAMFRNARLRLLMRLAGLERLDEDVLGASWMIPSSVPSSNLKEYHELIEKHCESPAEDIDGVDPRDLMRRKRTAADTDSSRHEFTENVNFGSDSEGEDDGVLFPPNLPERSKALKTLKQRRRRRRRSDDAEESGPDEAVLEARRTAREKNALERQRKIKSDLYVHASDDESDEEADIEFFAKEEMRRQAQARRVAEALETGMPENNTTKKKSKASAGRKRKVKPVLELDDDDSEASPPKRRRSDEVIESDSDGELMVGIGSTSPRRSQTPPTSADNIFGSEKSPSPMFPWSVGVDQMMAKLQGKDEASADNGESNEDEGEDVLSGTGRTRRRRTMGGFVIGSDSDS
What is the function of this protein?
Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair.  FPC coordinates leading and lagging strand synthesis and moves with the replication fork.  FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity).
What are the official names of this protein?
Topoisomerase 1-associated factor 1.
What is the protein family that this protein belongs to?
Belongs to the timeless family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARV1_YEAST
Sequence: MICITCMRPVDSLYTVYSNDHIQLTDCPYCQETVDKYVEIDNVLLFIDLLLLKAGAYRHLVFNALELHLSKYPKRKALNDCQCLRDYTQALLFNVKNWFCKYDRLNRLWLLLLSFEIYLTWVTEESKYIYYLNRNNNDGKLIMLSKKLPESFKWDSAIMRNTITSKVFTWSPPIQYLYFASYCILDVSLFHTFTQYFILKKLHWKHYSVSSKDVISYTILLSYGAKIFPILMLIWPYDTLISMSIIKWVANLYIIESLKIVTNLSYWNIIKIFISVSLLRYFMVKPILIVFVAKFNFSVIKNLIHQEFILLLQKSGTYLLL
What is the function of this protein?
Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.  Regulates also the sphingolipid metabolism.  Required for growth during anaerobiosis and sterol uptake.
What are the official names of this protein?
Protein ARV1.
What is the protein family that this protein belongs to?
Belongs to the ARV1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: CRTM_STAAB
Sequence: MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQASYTLHERVFVYKRKKAKLFHEINSKYHRI
What is the function of this protein?
Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress.  Catalyzes the head-to-head condensation of two molecules of farnesyl diphosphate (FPP) into the colorless C(30) carotenoid 4,4'-diapophytoene (dehydrosqualene).
What are the official names of this protein?
4,4'-diapophytoene synthase, DAP synthase, C30 carotenoid synthase, Dehydrosqualene synthase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family. CrtM subfamily.
Protein: ERPA_ECOSM
Sequence: MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: GEP5_YEAS1
Sequence: MASQVNALLLPVIESTPLHQITKVALTTTLTSKQSDYKFKEIAVPLTKSLQLYEKAQRRQDLRASLKALESIIYQTHFQWNNPLPRHAHLFQKHYHFLLTHWPFENHRDLVDSIAVNNGKLNSTSSRSVWLKADWITLFNVKNPWVQTPPSLMRLSGTDLDTFTPERIFLINSLGNHYKFLIANSHLSYNHKKYPSPGVQIPIRNALGEVSPAKQIAQLFARQLSHIYKSLFIENPPLSPENELALTAVFYDETVERRLRRLYMRACARAYTTTNADSTTEPLMFHCTRWEVD
What is the function of this protein?
Essential for respiratory growth and required for maintenance of mtDNA.  Required for cell survival in the absence of prohibitins (By similarity).
What are the official names of this protein?
Genetic interactor of prohibitin 5, mitochondrial, Required for respiratory growth protein 5.
What is the protein family that this protein belongs to?
Belongs to the GEP5 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MNME_BURA4
Sequence: MLATDSDPIVAIATAAGRGGIGVVRVSFGRGGEAAALPLIDALCGQQLAPRHASYVPFVDEHGAPLDRGIALYFPAPHSYTGEHVLELQGHGGPIVMQLLLQRCLDAGRGFGLRLAQPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAGRSLDGAFSRQIHALVEDVITLRMLVEATLDFPEEEIDFLEAADARGKLARIREQLAHVLGDARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDKVAQTIQVEGIPLHIIDTAGLRETEDEVERIGIARTWSEIERADVVLHLLDSRTGMTADDEVIAARFPGGVPVVRVLNKTDLTGVPACVEHPAAAGDLTEVHLSAKRGDGIDMLRAELLRIAGWQAGAEGVYLARERHLIALRAAQEHLAQAADHAEQRAQSLDLFAEELRLAQEQLNAITGEFTSDDLLGVIFSRFCIGK
What is the function of this protein?
Exhibits a very high intrinsic GTPase hydrolysis rate.  Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA modification GTPase MnmE.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDXH_EHRRW
Sequence: MITKDPIDLFNIWYQEVLKNYSKDPTAMVLATCSKDLKPSARVVLLKQHSDEGFVFFTNMNSRKGKEISENPFVSLVFDWRQISKQVRIEGKIETLSPEDSDRYYATRSRGSQISACCSKQSNILEDKQEFITNVQKMTKEFMGKPVPRPSYWMGLRVVPMLIEFWQEGVDRIHTRYQYTRTDKHGWSIVELYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: RS14Z_BACAN
Sequence: MAKKSMIAKQKRTPKFKVQEYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: PDLA_RHILO
Sequence: MSDTKVYLLDGGSLVLDGYHVFWNRGPGGEVRFPVYSILIEHAEGRFLIDTGYDYDHVMKVLPFEKPIQEKHQTIPGALGLLGLEPRDIDVVVNSHFHFDHCGGNKYFPHAKKICHRSEVPQACNPQPFEHLGYSDLSFSAEAAEARGATAQLLEGTTRANSTFEGIDGDVDLARGVKLISTPGHSIGHYSLLVEFPRRKPILFTIDAAYTQKSLETLCQAAFHIDPVAGVNSMRKVKKLAEDHGAELMYSHDMDNFKTYRTGTQFYG
What is the function of this protein?
Involved in the degradation of pyridoxine or pyridoxamine (free, phosphate-unbound, forms of vitamin B6).  Hydrolyzes 4-pyridoxolactone to 4-pyridoxic acid.  Has lower activity toward N-hexanoyl-D,L-homoserine lactone, but is not active toward 5-pyridoxolactone and gamma-butyrolactone.
What are the official names of this protein?
4-pyridoxolactonase.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: GUN_ECOLI
Sequence: MNVLRSGIVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVIDPSDARKITTSEGQSYGMFSALAANDRAAFDNILDWTQNNLAQGSLKERLPAWLWGKKENSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLGSMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFSPDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTEKNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNYVLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH
What is the function of this protein?
Hydrolyzes carboxymethylcellulose.
What are the official names of this protein?
Endoglucanase, Carboxymethylcellulase, CMCase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 8 (cellulase D) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOB_FLAPJ
Sequence: MITNQTERLNFASTKNIPAYPDFLDVQVKSFQDFFQLETKSDERGNEGLYNTFMENFPITDTRNNFVLEFIDYFVDPPRYTIQECIERGLTYSVPLKARLKLYCTDPEHEDFETIVQDVYLGTIPYMTPSGTFVINGAERVVVSQLHRSPGVFFGQSFHANGTKLYSARVIPFKGSWIEFATDINSVMYAYIDRKKKLPVTTLFRAIGFQSDKDILEIFDLAEEIKVSKSGLKKYIGRKLAARVLNTWHEDFVDEDTGEVVSIERNEIILDRDTILDKDNVEEIVESNVKSILLHKEDNNVVDYSIIHNTLQKDPTNSEKEAVEHIYRQLRNAEPPDEETARGIIDKLFFSDQRYNLGEVGRYRINKKLGLDTPMEKQVLTKEDIITIVKYLIELINAKADIDDIDHLSNRRVRTVGEQLSQQFGVGLARMARTIRERMNVRDNEVFTPIDLINAKTLSSVINSFFGTNQLSQFMDQTNPLAEITHKRRLSALGPGGLSRERAGFEVRDVHYTHYGRLCPIETPEGPNIGLISSLGVYAKVNGMGFIETPYRKVTNGVVDLTSVPKYLSAEEEEGMLIAQANIQMDENGKITADNVIARQEGDFPVIDPTAVHYTDVAPNQIASISASLIPFLEHDDANRALMGSNMMRQAVPLIRPEAPIVGTGLERQVASDSRVLINAEGAGVVEYVDADMITIKYDRTDAERAVSFESDEKTYKLIKFRKTNQGTSINLKPIVRKGDKVIKGQVLCEGYATQNGELALGRNLKVAFMPWKGYNFEDAIVISEKVVRDDIFTSIHVDDYSLEVRDTKLGNEELTNDIPNVSEEATKDLDENGMIRIGAEVKPGDILIGKITPKGESDPTPEEKLLRAIFGDKAGDVKDASLKASPSLHGVVLDKKLFARAVKDKRKRTQDKDALSDLEMEFEVKFVELKDKLVDKLFTIVNGKTSQGVMNDLGEEVLPKGKKYTQKMLYAVEDFAHLTRGQWVADDETNKMVNDLIHNYKIKLNDLQGALRREKFTITVGDELPAGILKLAKVYIAKKRKLKVGDKMAGRHGNKGIVARIVRHEDMPFLEDGTPVDIVLNPLGVPSRMNIGQIYETVLGWAGQNLGRKYATPIFDGASLDQINAITDEAGVPRFGHTHLYDGGTGERFHQAATVGVIYMLKLGHMVDDKMHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGASSTLREILTVKSDDVIGRAKTYEAIVKGETMPEPGLPESFNVLMHELKGLGLDIRLEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: ESXJ_MYCBO
Sequence: MASRFMTDPHAMRDMAGRFEVHAQTVEDEARRMWASAQNISGAGWSGMAEATSLDTMTQMNQAFRNIVNMLHGVRDGLVRDANNYEQQEQASQQILSS
What are the official names of this protein?
ESAT-6-like protein EsxJ.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. CFP-10 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: TIAS_METJA
Sequence: MVMMFIGIDDTDSPNKYCTTYIATLLIEELKGCGYSVDMPKLIRMNPMVKYKTRGNGGVAIHILDELYSKDKEEIKNITISLVEKYTDFECENTNPGIVFLDEAKYKENREKLTNYYKKVLYDIVSVDYAEKFILKVGGEFIKYKLGRGIIGALGAISSTPPYTYELLAYRKKEMWGKKREIDEKSVIEMDKETFPYTFDNYDYENEKILIAPNTPCPVLFGIRGIDAEILLKAMHKIEGEKPERFMIFKTNHGTDVHLRKMNIKDIYPNTGVIVYGRVVEEPRDIEGGHVIFKLSDGTGEIDCMAYEPTKGFRDIIRKLIVGDYIAVYGTVREKPLGINIEKIKILKLEKKFVKDKRCPYCGGTLKAKGKKAGYKCKKCKKTIAYDEIKMIEVERDLKTGFYEVPGSARRHLSKPIQLIDLI
What is the function of this protein?
ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
What are the official names of this protein?
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS, tRNA(Ile2)-agm2C synthetase, tRNA(Ile2) agmatidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the TiaS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPR3_RAT
Sequence: MMWGAGRSMAWFSAGSGSVNVSIDPAEEPTGPATLLPSPRAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAADFCIGSPEMSLVLVGVLATAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWVGALGLGLVPVLAWNCRDGLTTCGVVYPLSKNHLVVLAIVFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDANSPPLYTYLTLLPATYNSMINPVIYAFRNQDVQKVLWAICCCCSTSKIPFRSRSPSDV
What is the function of this protein?
Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP.  Has a potential role in modulating a number of brain functions, including behavioral responses to stress (By similarity), amyloid-beta peptide generation in neurons (By similarity) and neurite outgrowth.  Maintains also meiotic arrest in oocytes (By similarity).
What are the official names of this protein?
G-protein coupled receptor 3, G-protein-coupled receptor R4.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EXBL1_SYNY3
Sequence: MLDNCKRLLFRKFPCFLSMAPSPLFLTQTPRLLDEFLKGGVVMFPLLLLSILALTTAFERGWFWSRLLIQEDQVVRDVLDAAVEDLVKAREIAEHARHLAIGRFLLAPLKLRHPSPETFRLAMEATADKEFARMRRGDKLLETIIALAPLLGLLGTVTGLIRTFNNLNIGGGGSSAEATQAASGIGEALITTAAGMMVAIFALLVFRVLVSLQSQQMDYFAAVGSELELIYREVWYEPHQPMPNLLMAARIAEP
What is the function of this protein?
Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.  Protects ExbD from proteolytic degradation and functionally stabilizes TonB (By similarity).
What are the official names of this protein?
Putative biopolymer transport protein ExbB-like 1.
What is the protein family that this protein belongs to?
Belongs to the ExbB/TolQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NIPA2_PONAB
Sequence: MSQGRGKYDFYIGLGLAMSSSIFIGGSFILKKKGLLRLARKGSMRAGQGGHAYLKEWLWWAGLLSMGAGEVANFAAYAFAPATLVTPLGALSVLVSAILSSYFLNERLNLHGKIGCLLSILGSTVMVIHAPKEEEIETLNEMSHKLGDPGFVVFATLVVIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLAWILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGTLSGFFTIIVGIFLLHAFKDVSFSLASLPVSFRKDEKAMNGNLSNMYEVLNNNEESLTCGIEQHTGENVSRRNGNLTAF
What is the function of this protein?
Acts as a selective Mg(2+) transporter.
What are the official names of this protein?
Magnesium transporter NIPA2, Non-imprinted in Prader-Willi/Angelman syndrome region protein 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the NIPA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Early endosome. Note=Recruited to the cell membrane in response to low extracellular magnesium.
Protein: ATPL_LAWIP
Sequence: MVKLDPSSLGLAIFGCAIGMALAALGCGIGQGLGLKGACEGIARNPEASGKIQVALILGLAFIESLAIYALVINLIILFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EX7S_ECO81
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_SALA4
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNATDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: CLS_LISIN
Sequence: MGLLAYLLVILLILNVFFAAVTVFLERRDTSATWAWLLVLTFVPIFGFIIYLIFGRKLSGKKIFDWKGQEKIGIQESTANQIEMIRQKEFPFSDPNVKKHRDLIYLLLVNDGAILTQDNEVELFIDGHEKFDALIADIEKAKDHIHLIYYIFHSDELGNRLMRVLERKAAEGLNVKIIYDAMGSRTTKKSFFRTFEKNGGLVRPFFPSKLPLINFRLNYRNHRKLAIIDGDVGYIGGFNIGDEYLGRSKKFGYWRDTHLRVHGKAVYAMQTRFIMDWNSASSTHKIDYKARYFPTFHGKGHTSMQIVSSGPDSEWQQIKNGYIKMINAAKKTIYLQSPYFIPDASLLEAIKIAALSGVDVRVMIPNKPDHAFVYRATTNYAGELMETGAKIFIYDNGFIHAKTLVVDGEIASVGTANMDFRSFRLNFEVNAFIYEKKMVQKLEDAFLEDILKSYQLTPELYAKRSLWIKFKEAVSRLLSPIL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase, CL synthase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ECHB_PANTR
Sequence: MTTILTYPFKNLPTASKWALRFSIRPLSCSSQLRAAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSDVVPFKVPGKDTVTKDNGIRPSSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVEAYPK
What is the function of this protein?
Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway.  The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA.  Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids.  Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity.
What are the official names of this protein?
Trifunctional enzyme subunit beta, mitochondrial, TP-beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane. Mitochondrion outer membrane. Endoplasmic reticulum. Note=Protein stability and association with membranes require HADHA.
Protein: ALGX_AZOVI
Sequence: MKTHNSKWIGPAALAAAIALAAAGVRAEETPTGLPVYRAESCCDLCPAAADPNSYTSNYMKGFVTLVQGNESDWLFRTNEDLRTEFGTTPEGYRQLKALHDAFKSRGVELVIVYQPTRGMVQRNKLLPADYARFDYDKAVRNFRATLKHFEQLGYWVPDLTPLTDEKVEPAFYFRGDHHWTSYGAERSARIVAETVKEIPAFADIPRKEFVTKKMGRMGKRGTHHRVAGQLCNTTYAFEHSDQFFTEPKGEGGGDLFGDSSLPQITLVGTSHSGTNYNFAGFLSEYMGAEILNVAFPGSGLEGSMLKYLASDEFQKNPPKILIWEFSPLYDLAEDKFYRQALSMLGNACEGEKTLLAGKATLRPGEAGKEVLINGAGRLVEATNSRHQVDIRFSDPSVKKLEGTIWYMTGRREKFQFDKPVTTETNGRFAFNMRDEADWGGLNFFAMEIQPPEGLKEPVEVEVRLCKRHDYHAPANLTARSGN
What is the function of this protein?
Plays two roles in the biosynthesis of the exopolysaccharide alginate: protects alginate from degradation as the polymer traverses the periplasm, and also plays a role in its O-acetylation.  Probably has acetyltransferase activity in vivo (By similarity).
What are the official names of this protein?
Alginate biosynthesis protein AlgX, Probable alginate O-acetyltransferase AlgX.
What is the protein family that this protein belongs to?
Belongs to the AlgX family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MIAA_RUEPO
Sequence: MAVGAALPPIPEGAPVLIAGPTASGKSALALEIAERFGGVIVNADASQVYDCWRAISARPSPEEEARAPHLLYGHLPYDAPYSAGHWLREVTPLLDGTARPIIVGGTGLYFTALTEGMADIPATPPDVRAEADTLPLDRLLAGIDPATAAGLDRNNRARVQRAWEVERATGRALHLWQADTPPPPLPLARTVPLVLEVDKLWLWDRIARRFDQMLDQGALDEVAAMAARYDPALPAFKAIGVPELMAHLRGEITLDAARERASIATRQYAKRQRSWFRARMGDWHRLPVGG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.