PharMolix/UniProtQA huggingface dataset:
Protein: ACCA_ALKCK
Sequence: MSSEQEFEKPVIELRQKIADLRAFAMERDMDLSTEIKKMEARLSELEEEVYANLQPWERVQIARDHERPTTLDYVDVLFEDFLEMHGDRLFGDDKAIVGGIATYKGKPVTVIGHQRGKDTKENIVRYFGSPHPEGYRKALRLMKQAEKFKRPIICFIDTKGAYPGKAAEERGQSEAIARNLLEMAGLKVPTISIVIGEGGSGGALALGVADEIHMLENATYSVISPEGAAAILWKDAGKAKKAAESMRITAPDLYELGIIDSIIPEPRGGAQRNLHQQADEIDRLLEKALTRLAEKPVDVLLDERYEKFMKIGHIPEEAATTGQ
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS62_PSEAE
Sequence: MVRRRVIPCLLLKDRGLVKTVKFKEPKYVGDPINAIRIFNEKEVDELILLDIDASRLNQEPNYELIAEVAGECFMPICYGGGIKTLEHAEKIFSLGVEKVSINTAALMDLSLIRRIADKFGSQSVVGSIDCRKGFWGGHSVFSENGTRDMKRSPLEWAQALEEAGVGEIFLNSIDRDGVQKGFDNALVENIASNVHVPVIACGGAGSIADLIDLFERTCVSAVAAGSLFVFHGKHRAVLISYPDVNKLDVG
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity).
What are the official names of this protein?
Putative imidazole glycerol phosphate synthase subunit hisF2, IGP synthase cyclase subunit, IGP synthase subunit hisF2, ImGP synthase subunit hisF2, IGPS subunit hisF2.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDJI_ECOLI
Sequence: MLADIRYWENDATNKHYAIAHFNVWNAEMLMGVIDAAEEAKSPVIISFGTGFVGNTSFEDFSHMMVSMAQKATVPVITHWDHGRSMEIIHNAWTHGMNSLMRDASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAEFVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKTAISLGIAKINIHTELCQAAMVAVKENQDQPFLHLEREVRKAVKERALEKIKLFGSDGKAE
What are the official names of this protein?
Uncharacterized protein YdjI.
Protein: PGK_LEUCK
Sequence: MAKLTVSDLELSGKKVLMRVDFNVPIKAGVIGNDNRIVAALPTIKYVLENNGRAILFSHLGRIKSEDDKKELSLAPVAARLGELLGKNVKFVPHTRGEELESAINALQDGEVLMVENTRFEDVVDGVEVKNESKNNPELGKYWAGLGDDLFINDAFGTAHRAHASNVGIASNVSQVAAGFLMEKEIKFLGDAVANPVRPFVAIIGGAKVSDKIEIVKSLLAKADKVIVGGGMAYTFDAAKGEKIGNSLFEADKVELAKELMAEAGDKLVLPVDSIAADAFSNDAKTEVVDATAGIPDGYMGLDIGPKSVKLLQDTLADAKTVVWNGPMGVFEMPNFAKGTLAIGEELVKVTENGGTTIVGGGDSTAAVQQLGVADKLSHISTGGGASLEYLEGKELPGIASISEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JAK2_CHICK
Sequence: MACLTMANIEGSATATVHQNGDILGNTSAPKQTEPLLQVYLYYSPGKTGGDYLQFPAGEYVAEEICIVACKACGIMPVYHNMFALMSETERVWYPPNHIFHVDEATRLKLLYRIRFYFPHWYCNGTSRACRYGIIRGSESPVLDDLVMSYLFAQWRKDFLDGWIQMPVTHETQEECLGMAVLDMMRVAKEKDQTPLAVYNSVSYKMFLPKCVRAKIQEYHILTRKRIRYRFRKFIQQFGQCKATARNLKLKYLINLETLQSAFYSEVFEVKEPGGDPSGEESFATIVITGNGGIQCSRGKLKNCETLAEQDLQTYCDFPDIIDVSIKQASQEGSSERRIVTIHKQDSKNLEAEFQSLREALSFVSLIDGYYRLTADAHHYLCKEVAPPSVLENIQSNCHGPIFMDFAINKLKKAGNQTGFYVLRCSPKDFKKYFLTFAIERENATDYKHCLITKNENGEYNLSGTKRSFGNLKDLLTCYQTETVRSDSIIFQFIKCCPPKPKDKSNLLVFRSNSVSDVPSSPTLQRHNVSQMVFHKIRNEDLIFEESLGQGTFTKIFKGIRKEVGDYGQLHQTEVLLKVLDKVHRNYSESFFEAASMMSQLSYKHLVLNYGVCVCGEENILVQEYVKFGSLDTYLKKNKNVINILWKLEVAKQLALAMHFLEDKGLVHGNVCAKNILLIREEDRKSGNLPFIKLSDPGISITVLPRDILLERIPWVPPECIENPRQLSLATDKWSFGTTLWEICSGGDKPLSALDSSRKLQFYEDRHQLPAPNWTELANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNIRTGALGFSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERLDHKKLLLYASQICKGMEYLGTKRYVHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYAIMKECWNNNVAQRPTFRDLAQRVDQIRDNMGG
What is the function of this protein?
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications.  Mediates essential signaling events in both innate and adaptive immunity.  In the cytoplasm, plays a pivotal role in signal transduction via its association with cytokine receptors.  Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins.  Subsequently, phosphorylates the STATs proteins once they are recruited to the receptor.  Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription.  For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain.  Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.  Once activated, dimerized STAT5 translocates into the nucleus and promotes the transcription of several essential genes involved in the modulation of erythropoiesis.  Part of a signaling cascade that is activated by increased cellular retinol and that leads to the activation of STAT5 (STAT5A or STAT5B).  In the nucleus, plays a key role in chromatin by specifically mediating phosphorylation of 'Tyr-41' of histone H3 (H3Y41ph), a specific tag that promotes exclusion of CBX5 (HP1 alpha) from chromatin.
What are the official names of this protein?
Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Nucleus.
Protein: OR1J1_HUMAN
Sequence: MSPENQSSVSEFLLLGLPIRPEQQAVFFALFLGMYLTTVLGNLLIMLLIQLDSHLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQHLAVFYKGCISQTYFFIFFADLDSFLITSMAYDRYVAICHPLHYATIMTQSQCVMLVAGSWVIACACALLHTLLLAQLSFCADHIIPHYFCDLGALLKLSCSDTSLNQLAIFTAALTAIMLPFLCILVSYGHIGVTILQIPSTKGICKALSTCGSHLSVVTIYYRTIIGLYFLPPSSNTNDKNIIASVIYTAVTPMLNPFIYSLRNKDIKGALRKLLSRSGAVAHACNLNTLGG
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 1J1, Olfactory receptor OR9-18.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATPF1_CHESB
Sequence: MFVAPAFAQEADHTAGETHTETGVAEGGHEGGFPPFLVETYPSQLLWLAITFGLFYLFLKRVVLPRIAGILEVRSDRIAQDLDQAARMKEDADAAVAAYEQELAEARKKAAAIAQEARDTAKAEAAAERRKVESGLDSKLKEAEARIALIKDTALSDVGTIAEETAAAIVQELVGGKVDKASLSAAVKAVQQQ
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GRK1_HUMAN
Sequence: MDFGSLETVVANSAFIAARGSFDGSSSQPSRDKKYLAKLKLPPLSKCESLRDSLSLEFESVCLEQPIGKKLFQQFLQSAEKHLPALELWKDIEDYDTADNDLQPQKAQTILAQYLDPQAKLFCSFLDEGIVAKFKEGPVEIQDGLFQPLLQATLAHLGQAPFQEYLGSLYFLRFLQWKWLEAQPMGEDWFLDFRVLGKGGFGEVSACQMKATGKLYACKKLNKKRLKKRKGYQGAMVEKKILMKVHSRFIVSLAYAFETKADLCLVMTIMNGGDIRYHIYNVNEENPGFPEPRALFYTAQIICGLEHLHQRRIVYRDLKPENVLLDNDGNVRISDLGLAVELLDGQSKTKGYAGTPGFMAPELLQGEEYDFSVDYFALGVTLYEMIAARGPFRARGEKVENKELKHRIISEPVKYPDKFSQASKDFCEALLEKDPEKRLGFRDETCDKLRAHPLFKDLNWRQLEAGMLMPPFIPDSKTVYAKDIQDVGAFSTVKGVAFDKTDTEFFQEFATGNCPIPWQEEMIETGIFGELNVWRSDGQMPDDMKGISGGSSSSSKSGMCLVS
What is the function of this protein?
Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade (PubMed:15946941).  This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination (By similarity).  May play a role in the maintenance of the outer nuclear layer in the retina (By similarity).
What are the official names of this protein?
Rhodopsin kinase GRK1, RK, G protein-coupled receptor kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor. Cell projection, cilium, photoreceptor outer segment. Note=Subcellular location is not affected by light or dark conditions.
Protein: FBSL_HUMAN
Sequence: MEAKVRPSRRSRAQRDRGRRREAARDARAQSPSSGDEPEPSPGKENAGLRGAPPRGAAPAPRTARPPRRRRRESSSQEEEVIDGFAIASFSTLEALEKDMALKPHERKEKWERRLIKKPRESETCPPAEPSENRRPLEAGSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAVSGRGYSCDSESGPDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKVSGLERSRELSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPPAPHRHTPQPPPPQPRGLLPTHVPASLGAFAGHSQAAANGLHGLSRSSSAPLGLGKHVSLSPHGPGPHLSTSHLALRSQAQHQLHAAMFAAPPTLPPPPALPASSLVLPGHPADHELLRQELNTRFLVQSAERPGASLGPGALLRAEFHQHQHTHQHTHQHTHQHQHTFAPFPAGLPPTPPAAPPPFDKYAPKLDSPYFRHSSVSFFPSFPPAIPGLPTLLPHPGPFGSLQGAFQPKVSDPYRAVVKVSTCWEGPWQGRTLVPPGRPRGARDSRSLQKTWVGVAPAPLSASILSQKPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARPLFPSTGAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGGLGSHALAPGGSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDNGKEEQERDLLEKTRLLSRASPATPAGHPVSGLLLRAQSELGRSGAPAEREAEPRVKESRSPAKEEAAKMPARASPPHSKAAPGDVKVKEERGEDEASEPPAGGLHPAPLQLGLGRERLGAPGFAWEPFRGLELPRRAFPAAAPAPGSAALLEPPERPYRDREPHGYSPERLRGELERARAPHLPPAAPALDGALLPSLGALHFPRLSPAALHNGLLARTPPAAAALGAPPPLVTAAGPPTPPGPPRSRTTPLGGLGPGEARDYSPSRNPPEVEAR
What are the official names of this protein?
Fibrosin-1-like protein, AUTS2-like protein, HBV X-transactivated gene 9 protein, HBV XAg-transactivated protein 9.
What is the protein family that this protein belongs to?
Belongs to the AUTS2 family.
Protein: TRPF_PSEAB
Sequence: MPAVRIKICGITRVEDALAAAAAGADAIGLVFYAKSPRAVDIHRAREIVRALPPFVTSVGLFVNASRCELGEILDAVPLDLLQFHGDERAEDCEGHRRPYLKALRMKPGDDIVGRAAAYPGAAGILLDTYVEGVPGGTGAAFDWSLVPADLGKPLVLAGGLTPDNVGRAVEQVKPYAVDVSGGVEASKGIKDAARVRAFVDAVRSRRRDET
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: TATA_TROW8
Sequence: MGNVFSGWHLLVILLVIVLLFGTSRLPKLSKSVVEALKIFRRSFNEASDITRSQDGHPDSQGNFAESASSVPFVKSEKQSEKRASVTEAKKSK
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: BIOB_AGRFC
Sequence: MDQLATQIDGKPASIPAVETSSSLEEAKIIYNLPFNDLLFRAQQVHRCHFDANAIQMSRLLSIKTGGCPEDCSYCSQSARNPTGLKASKLMEVERVLAEARKAKEGGATRYCMGAAWRNPKERDMEAVVAMVEGVKALDMETCMTLGMLTPEQSERLADAGLDYYNHNVDTSERFYSEIITTRTFEDRLETLANVRDAGIKVCAGGILGMGETVEDRISMLVTLANLPVPPESVPINMLIPIPGSKLANADPVDPIDFVRTIALARILMPRSHVRLSAGRTEMSDETQALCFLAGANSIFIGETLLTADNPGEDHDTALFRRLGLKPMELQSSEAGGCR
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: ISPD_BORBR
Sequence: MSESLIAIVPAAGIGARASLPGEAAVPKQYRPLAGQPMLRHAVRALLADPRIVQVRVAVSAGDGWVEQALAGLPRTVWRPCGGPNRADTVAAALADSGAAADDWILVHDAARPGLPAAALARLIDACLDDAVGGLLALPVADTVKAGRQRVSRTVDRDGLWLAQTPQMFRAGLLRDALARARAAGLAVTDEASAVEAAGHAPRLVAGALRNFKVTWPDDFELMEKWL
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: RL22_SALPK
Sequence: METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PDXJ_PSEP1
Sequence: MLLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVVLLKDVLQTRMNFEMGVTEEMMAFAEKIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLARTGAEVSLFIDADERQIEASRRVGAPAIELHTGRYADAETPTEVAEELQRIVEGVAFGVGHGLIVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALIVAASR
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TICK1_RHIAP
Sequence: MASTLKLFMLLPVILLLLQEAYGTIDVEARGDNFNCNKREGPCSQRSLCECDPNLQLGRHSDQLWHYNLRTNRCERGGYRDNCNSHTSSGACVMACER
What is the function of this protein?
Activates large conductance calcium-activated potassium channels (maxiK, KCNMA1/KCNMB), when tested at micromolar concentrations, suggesting a potential mechanism for regulating host blood supply during feeding (PubMed:19394347).  Shows no antiprotease activity, and does not prevent ADP-, PAF- or collagen-induced platelet aggregation (PubMed:19394347).  Has no effect on blood coagulation and does not inhibit the alternative or classical complement cascades (PubMed:19394347).
What are the official names of this protein?
R.appendiculatus Kunitz/BPTI-like protein, Ra-KLP, Kunitz/BPTI-like protein, Pancreatic trypsin inhibitor.
What are the subcellular locations of this protein?
Secreted.
Protein: Y1218_KLEP7
Sequence: MSITAKSVYRDTGNFFRNQFITILLIALLCAFITVVLGHAFSPSDEQLSILSEGDNLAGSAGLFELVQNMTPEQQQVLLRASAASTFSGLVGNAILVGGVLLLIQLVSAGHRVSALRAIGASAPVLPKLLLLILFTTFLVQMGMMLVLVPGVLLAIVLAFAPIMLVQDNMGILGAMRSSMRLAWANLRLVAPAIIGWLVAKTLLLLFASSFAALTPNVGAVVINTISNLISALLLIYLFRVYMLIRS
What are the official names of this protein?
UPF0259 membrane protein KPN78578_12180.
What is the protein family that this protein belongs to?
Belongs to the UPF0259 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRA_VITST
Sequence: ARAIRVHGKLEPIYVETVAELPEASRLYTVRARCERSPLCVCRWRKFHHISAWPLSKTLDFFQNLDLGGNKQQIAEKVLKEITERLGFLINVGLNYLSLARSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLGTLKHLRDLGNSVIVVEHDEDAIRAADYVVDMGPGAGELGGAVLIADTPEKIAACEQSITGRYLSGKEAIYIPAQRTPKDAERMLVLKGASGQNLKDVTLELPLGLMTCITGVSGSGKSTLINDTLAKIAQRDLNRATKDEPSPYTEIQGLEQLDKVINVDQSPIGRTPRSNPATYTGVFTPIRELFAGVPVSRERGYNVGRFSFNVKGGRCEACQGDGVLKVEMHFLPDVYVPCEVCHGKRYNRETLEILYKGKNIHQVLEMTVAEAHAFFEAVPTLSRKLQTLMDVGLSYVRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLLEVITRLKGKGNSIVIIEHNLDVIKTADYIIDLGPEGGDGDGGGRIIAQGTPEDVAATAGSYTGQYLSQVLANSQTAAV
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrA is an ATPase and a DNA-binding protein.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity).
What are the official names of this protein?
UvrABC system protein A, UvrA protein, Excinuclease ABC subunit A.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. UvrA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_DANRE
Sequence: MPCHNQQLNNNSESPEHAAKHVRFAQSSAAAAETCQNDAEQPEYQTTSEIHQQIGPQLKLLPLNDQIRELQTIIRDKTTSRGDFVFCADRLIRLVVEEGLNQLPYSECTVTTPTGHKYEGVKFEKGNCGVSIMRSGEAMEQGLRDCCRSIRIGKILIQSDEETQKAKVYYAKFPPDISRRKVLLMYPILSTGNTVIEAVRVLTEHGLQAKHIILLSLFSTPHGARSIVQEFPDITILTTEVHAVAPTHFGQRYFGTD
What are the official names of this protein?
Uracil phosphoribosyltransferase homolog.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CASS4_PIG
Sequence: MKGAGGPDGAPKALLARALYDNHPDCSDELAFCRGDILTILEQDVPESEGWWTCLLHGRQGLAPANRLQILEEAPADGPCPPFFGGLEEAPGRSQENYEVPSPPTPGPVYEQMKSWVEGPPPPTVQIYEFPDPPTCARIVCEKTLSFPKQAIFTIPRAARTSLPALPCQVYDVPAQSRCPPASKEPGKQQLYDIPPSRQKATLGPLSSQANGQNVPLTSATALRRGGCNTLPNPQKSEWIYDTPVSLEKAGVQKASLANSGEELGHRGLPRYMSSFHSPPNSIARSHPPHPQKNGPMQKKLSLPEIPCYSFPPPKCMFPLDESVSYKVPSSFLIPRVEQQNTTPNIYDVPRAMPDVPQAGKELGKAGGPSENSVDHSSSWFCSRAASLSPEPDSISVSSSDSRASVLSSCSSTSTDSSSSSFSEEAAKELPLDLDSAKETVTALQHKVASSVSSLMHFVSRKWRFRDSLEANIDAIRRATDRIEESLREFLDFAHGVRGTAGNLTDSNLQTKIRDQLQTIANAYQILLETKERLESCGWSLEVLATDKVQNSPDDLERFVLVARTVPEDIKRFASIVIANGRLLFKSNCEKEEPVQWTPNAEFKLARRIQLPQKEGESYQRKAPFQKQRASEQPPELIEKNKTNACGQNPGSLIPRPLSQQNPEKRIHLSEHCRLYFGALLKAIGVLNGSLSNRQPPETFITQSKLIIMVGQKLVDTLCKETQERDFRNEILCGSSHLCSLLRNLALATKHAVLEYPSPAALGHLQAEARKLEQHTQQFRGTLE
What is the function of this protein?
Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading.  Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity).
What are the official names of this protein?
Cas scaffolding protein family member 4.
What is the protein family that this protein belongs to?
Belongs to the CAS family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell junction, focal adhesion.
Protein: MDTB_EDWTE
Sequence: MSQTPSSPVPRGGGPSRLFILRPVATTLLMIAILLAGLVAYRALPVSALPQVDYPTIQVVTLYPGASPDVTASAITAPLERQFGQMSGLQQMSSQSSGGASVITLQFQLSLALDVAEQEVQAAINAATNLLPNDLPYPPIYSKVNPADPPILTLAVVSDALSLPQVEDLVETRISQKIAQVGGVGLVTLAGGQRPAVRVRLNGAAAAAYGLSSETIRSAIANANVNSPKGSLDGPTRAITLNANDQLRSAQEYQNLIVAYRSGAPVYLRDIASVEQGAENTQLAAWANNHPAIVINVQRQPGANVIATADAVLAQLPQLRESLPASVKISVLNDRTQTIRASVSDVRHELLLAVALVVMVIYLFLRNLPATLIPGVAVPLSLIGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIVVIENIERHLENGDPPLRAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIIGRLFREFAVTLAVAILISAVVSLTLTPMMCARLLSQESLRRQNRFSLACERQFQRLIAGYGRALRLALRHPRITLGVAVATLMLTVLLYLIIPKGFFPQQDNSLIQGTVYAPQSISFSAMAERQRQLSEALLRDPDVASVSAFVGVDGVNPALNSGRLQIVLKPLADRRDRIDRIIPRLQALAARVGGISLYLQPVQDMTIDTLPGRARYPFTLQAMSLDELQTWVPRLQARLAQSPMLKDVNSDWQDQGLVAYVNVNRDSASRLGIAMQDVDNALYNAFGQRLISTIYTQSNQYRVVLEQERAHQDGLTALQRIYLTAADGSAIPLASIATVEQRHGVLAINHLDQFPSATLSFNVPDGYTLEQAIAEIDAARRAIGMPADMTLHFQGAALAFQSALDSTLWLILAAIVAMYIVLGILYESFIHPITILSTLPSAGVGALLALMISGQALDVIAIIGIILLIGIVKKNAIMMIDFALAAERTQGMAPHDAIYQACLLRFRPILMTTMAALLGALPLMFSQGVGAELRQPLGICMVGGLIVSQILTLFTTPVIYLAFDRLARNTHRPTRGVPAR
What are the official names of this protein?
Multidrug resistance protein MdtB, Multidrug transporter MdtB.
What is the protein family that this protein belongs to?
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NDK2_ARATH
Sequence: MVGATVVSKWTPLCVASPPERNSASLNPHCSPARVNFRTALAAFRPQFRLFSRNSASRRRLRASSSAESGIFLPHLVASMEDVEETYIMVKPDGIQRGLVGEIISRFEKKGFKLIGLKMFQCPKELAEEHYKDLSAKSFFPNLIEYITSGPVVCMAWEGVGVVASARKLIGKTDPLQAEPGTIRGDLAVQTGRNIVHGSDSPENGKREIGLWFKEGELCKWDSALATWLRE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.  May activate MPK3 and MPK6.  May be involved in the regulation of cellular redox state and hydrogen peroxide-mediated MAP kinase signaling.
What are the official names of this protein?
Nucleoside diphosphate kinase II, chloroplastic, NDK II, NDP kinase II, NDPK II, NDPK Ia.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YKW3_YEAST
Sequence: MEMLLFLNESYIFHRLRMWSTVLWHSCVFVCVECENANYRVPRCLIKPFSVPVTFPFSVKKNIRILDLDPRTEAYCLSPYSVCSKRLPCKKYFYLLNSYNIKRVLGVVYC
What are the official names of this protein?
Putative UPF0377 protein YKL223W.
What is the protein family that this protein belongs to?
Belongs to the UPF0377 family.
Protein: Y1188_METJA
Sequence: MMKIGVSTLFFWEYPMVEIFDIFRDIGIKCMEFFPENPDFWDNRFDLDYIADLRKEFLKFDVALHNPHIELNPSSLNPYVREAVIKETLWSIELAKFYRCKLITIHPGKRPTNRSPTDEEYEAFFKYLDRTLEVAINKNITICVENMPERINRIGWSPEEMEWILKRYDELLYMTLDFAHAKEYMEEFLESVIDYIKHTHISGVVNRKDHFPLRKSEIDFSPYIKALLDYGYNGMFNLELDDRRLEKNPVTKEEKIEEVIKDIEFLESII
What are the official names of this protein?
Uncharacterized protein MJ1188.
Protein: HIS6_SHEPC
Sequence: MLAKRLVPCLDVKDGKVVKGVQFRNHEIVGDIVPLAARYAEEGADELVFYDITASAHERVVDKSWVSRVAEQIDIPFCVAGGIKTISQARELLAFGADKISINSPALTDPSLISRLQDEFGRQCIVIGIDSFFDASSNSYKVKQFTGDEAATKDTQWFTQDWVEEVQKRGCGEIVLNVMNQDGVRGGYDIKQLSLVRAICDVPLIASGGAGAMAHFRDVFIEAKVDAALAASVFHKAIINIGELKAYLAAEGIAIRR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTA1_PIG
Sequence: MAGKPILHYFNGRGRMECIRWLLAAAGVEFEEKFIKTPEDLDKLTNDGSLLFQQVPMVEIDGMKLVQTRAILNYIATKYNLYGKDAKERALIDMYTEGVADLGEMILLLPLCPPNEKDAKVASIKEKSTNRYLPAFEKVLKSHGQDYLVGNKLSRADIQLVELLYYVEELDPSLLANFPLLKALKTRVSNLPTVKKFLQPGSQRKPPMDAKKIRRSQEYFPD
What is the function of this protein?
Glutathione S-transferase that catalyzes the nucleophilic attack of the sulfur atom of glutathione on the electrophilic groups of a wide range of exogenous and endogenous compounds.  Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2).  It also catalyzes the isomerization of D5-androstene-3,17-dione (AD) into D4-androstene-3,17-dione and may therefore play an important role in hormone biosynthesis.  Through its glutathione-dependent peroxidase activity toward the fatty acid hydroperoxide (13S)-hydroperoxy-(9Z,11E)-octadecadienoate/13-HPODE it is also involved in the metabolism of oxidized linoleic acid.
What are the official names of this protein?
Glutathione S-transferase alpha M14, GST class-alpha.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Alpha family.
What are the subcellular locations of this protein?
Cytoplasm.