PharMolix/UniProtQA huggingface dataset:
Protein: MNMA_CUPMC
Sequence: MSGKRVVVGLSGGVDSSVTAWLLKQQGYEVIGLFMKNWEDDDDSEYCSTRQDWLDVASVADVIGVDVEAVNFAAEYKDRVFADFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMSLGANTIATGHYARVRQAANGKFELLKAFDHTKDQSYFLHRLNQAQLSRTLFPLGEIPKTRVREIAAEIGLPNAKKKDSTGICFIGERPFRDFLNRYLPTQPGPMKTPEGKVVGEHIGLAFYTLGQRKGIGLGGSRDGSGDAWYVARKDMASNTLYVVQGHDHPWLLTSELNAADLSWVAGEPPAAGATMAAKTRYRQSDAPCRVVAAEGDALKLSFAEPQWAVTPGQSAVLYDGDVCLGGGIIQ
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2A_PHANO
Sequence: MTGGKSGGKASGSKSSAQSRSSKAGLAFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGHVTIAQGGVLPNIHQNLLPKKTAKPGKGPSQEL
What is the function of this protein?
Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GAL1_CROS8
Sequence: MSLKEKTHALFAEKFGYPATTHIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAKRDDRRVRVVAADYDNETDEFSLDEPILTHDSQQWSNYVRGVVKHLQQRDPGFGGADLVISGNVPQGAGLSSSASLEVAVGTVFRHLYHLSLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVPMPQGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFTQKALRDVSLDQFNAVAHELDPIVAKRVRHVLTENARTVEAADALAKGNLTRMGELMAESHASMRDDFEITVPQIDTLVEIVKSVIGDKGGVRMTGGGFGGCVVALVPEALVPEVQAAVEAQYEARTGIKETFYVCKPSEGAGLC
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLHC_PROMI
Sequence: MSEKSIVREAKDIRLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNIHSSMFYNAYRFLLKSGGSVGIEAVVKAYRLYLEQCPPVKDQEPILALTRAWTLVRFVESGMLQLSVCTKCNGSFITHAHQPASNYVCSLCQPPSRAIKKRKLSANPADINLQLLDGLEQFRM
What is the function of this protein?
Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region.  Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes.  Also regulates genes whose products function in a variety of physiological pathways.
What are the official names of this protein?
Flagellar transcriptional regulator FlhC.
What is the protein family that this protein belongs to?
Belongs to the FlhC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MYO3A_MOUSE
Sequence: MLPLIGKTIIFDNFPDPSDTWEIIETIGKGTYGKVFKVLNKKSGQKAAVKILDPIHDIDEEIEAEYNILRTLSDHPNVVRFYGIYFKKDKINGDKLWLVLELCNGGSVTDLVKGFLKRGERMSEPVIAYILHEALMGLQHLHSNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLSSTRHRLNTSVGTPFWMAPEVIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLAELHPMRALFKIPRNPPPKLRQPELWSAEFNDFISKCLTKDYEKRPTVSDLLKHKFITQIEGKDVILQKQLMEFIDIHQCLGSTEKARHERIHTKKGNLNRSLISSLKDVDDLATLDVLDEPTASPHLHPCHSRDQIHIHVADILIALNPFQSLGIYSPKLSRLYIGAKRTANPPHIFAMADLGYQSMVTYNADQCIVISGESGAGKTESAHLLVQQLTVLGKANNRTLQEKILQMNNLVEAFGNACTIINDNSSRFGKYLEMKFTSSGAVVGAQISEYLLEKSRVIHQAMGEKNFHIFYYIYGGLAEKKKLALYKSPEHKPPRYLQNDNLRTVQDMMNNSFYKSQYELIEQCFKVIGFTMEQLASVYSVLAAILNVGNIEFSSVATEYQMDKSYICNHTALENCASLLCIQADELQEALTSHCVVTRGETIIRPNTVEKAADVRDAMAKTLYGRLFSCIVNCINSLLKHDTSPSGDEELNIGILDIFGFENFKRNSFEQLCINIANEQIQYYFNQHVFAWEQNEYLNEDVDARVIEYEDNRPLLDMFLQKPMGLLSLLDEESRFPKATDQTLIEKFEDNLKSQYFWRPKRMELSFGIHHYAGKVLYSASGFLAKNRDTFPTDIVLPLRSSENSVIRQLVNHPLTKTGNLPLSKTKNIVNYQMWNSEKSTNLTKGETRDVTCHACETTNVKTQTVSSYFRYSLMDLLSKMVVGQPHFVRCIKPNNERQARKYDKEKVLLQLRCTGILETARIRRLGYSHRILFANFIKRYYILCYKSSEEPPVSPDTCAAILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEATNKLVLIQASVRAFLGARRYQELQQKRKSSAVIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQTENAVPTNESNTSTPNNKESPSAGKTAPFIAESKATNVESNNRRYHTQKKMSNVYAEGQNQELYIVEDTWAEVSPRQKYVQDLEESRKMRKEEKGDAVIQSYCQWYTEGSNFEESKATCLEGRETWERTSCPGLWLTEEIYLRKTLDPTLSQKSVYQNADGKEKEHKVSVVTQNAPLGNLERDYHLLGFLGEEDTGPVPQAQEEHKAVSIHSKYQSSKKKQQLGKDRLAPPFKNQKILSSSTEVAKTTHNVYPCPTKQEGVHHSKMVDERDSKMASKKEAWDLAMFSRQISKLSEEYFILQKNLNEIILAQQLKPFYLGIYRHKPINRHVSTHQYLSGVSKGEEPKILRPPRRPRKPKTLNNPEDSTYYYLLHKSTQEEKRRPGKDSQGKLLGLEDFYYKEFLPTHYGPKAHSSNAREWKALKEPQAQPIESNERCWTTSENESLEEERISANPYDYRRLLRKTSQRQRLVQQL
What is the function of this protein?
Probable actin-based motor with a protein kinase activity.  Probably plays a role in vision and hearing (By similarity).  Required for normal cochlear hair bundle development and hearing.  Plays an important role in the early steps of cochlear hair bundle morphogenesis.  Influences the number and lengths of stereocilia to be produced and limits the growth of microvilli within the forming auditory hair bundles thereby contributing to the architecture of the hair bundle, including its staircase pattern (PubMed:26754646).  Involved in the elongation of actin in stereocilia tips by transporting the actin regulatory factor ESPN to the plus ends of actin filaments (PubMed:19287378).
What are the official names of this protein?
Myosin-IIIa.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm. Cell projection, filopodium tip. Cell projection, stereocilium. Note=Increased localization at the filodium tip seen in the presence of MORN4.
Protein: VNFG_AZOSA
Sequence: MSQSRLDDLFAYVEERCLWQFFSRTWDREENIEGVLNQVCRLLTGQEPLRGTPQERLFYADALAMANDVRERFPWASQVNKEEIAFLIDGLKSRLVDVTITRSTNRELNHHLY
What is the function of this protein?
The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein.
What are the official names of this protein?
Nitrogenase vanadium-iron protein delta chain, Dinitrogenase 2 subunit delta, Nitrogenase component I.
Protein: TBL17_ARATH
Sequence: MTLASPRVSNSKTTVLLFPRKVSSIAFAIGGLTSFVIFASLLLFTYPIGSSVTDYFYRTETTQNVQFHHSIHDPDRNPSPVSSSESPPVLTQDSDDKVLPKGSHDSNDVRLGEETNSGKSSNVSIDEEATQDHVETECDLYHGNWFYDPMGPLYTNNSCPLLTQMQNCQGNGRPDKGYENWRWKPSQCDLPRFDAKKFLELMRGKTLAFIGDSVARNQMESMMCLLWQVETPVNRGNRKMQRWYFRSSSVMIARMWSSWLVHQFNEPFGFATDGVTKLKLDQPDERIIEALPNFDVVVLSSGHWFAKQSVYILNDQIVGGQLWWPDKSKPEKINNVEAFGISVETIIKAMAKHPNYTGLTILRTWSPDHYEGGAWNTGGSCTGKVEPLPPGNLVTNGFTEIMHEKQATGFHRAVADDKLGNRSKKLKLMDITEAFGYRHDGHPGPYRSPDPKKITKRGPDGQPPPQDCLHWCMPGPVDTWNEMVLEIIRRDFEGRQSSPSS
What is the function of this protein?
May act as a bridging protein that binds pectin and other cell wall polysaccharides.  Probably involved in maintaining esterification of pectins (By similarity).  May be involved in the specific O-acetylation of cell wall polymers (By similarity).
What are the official names of this protein?
Protein YLS7, Protein TRICHOME BIREFRINGENCE-LIKE 17, Protein YELLOW-LEAF-SPECIFIC GENE 7.
What is the protein family that this protein belongs to?
Belongs to the PC-esterase family. TBL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RODZ_YERE8
Sequence: MNTEASQDQTVPETTGVRLRQAREALGLTQQMVAERLCLKVSTIRDIEEDKAQANLASTFHRGYIRSYAKLVHLPEDELLPMLAKQAPIRAAKVAPMQSFSLGKKHKKRDGWLMSFTWLIVLVVLGLTGAWWWQNHQAQQAEIVTMADQSSAQLSQNGGQSVPLSDDNSDPANPVDTQAPVANSQPSTPTENGTVPATSSAAPADTANNGVNTTAPQGTTSAESAVVSPSQAPLPSVSTAQPPLPTADAGVTGTASSADSLVMNFTADCWLQVVDASGKTLFSGIQKGGATLNLSGKAPYKLTIGAPGALTITYQGNPVDLSKFIKANRVARLTVGVE
What is the function of this protein?
Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis.
What are the official names of this protein?
Cytoskeleton protein RodZ.
What is the protein family that this protein belongs to?
Belongs to the RodZ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Forms helical filaments along the long axis of the cell.
Protein: RUVA_BRASB
Sequence: MIGKLKGLIDSYAEDFVILDVGGVGYQVHCSARTLQALPSPGEAATLSIETYVREDQIKLFGFRSDVEREWFRLLQTVQGVGAKVALAVLGTLPPADLANAIALRDKAAVARTPGVGPKVAERIVTELKDKAPAFADVDPGVIRLSGAIEDSRAPQPIADAISALINLGYGQPQAAAAIAAASRAAGDKAETAQLIRLGLKELAK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: NIA2_BRANA
Sequence: MATSVDNRHYPRLNPAINGVVRSFKPPPIPSPRHQNKTVSFLTEKVIVKETKNDAVDDSYDSSDDEDESHNRNVSYYKEMIRKSHSDVEPSILDSRDESTADNWIHRNSSMVRLTGKHPFNAEPPLPRLMHHGFITPVPLHYVRNHGTVPKADWSEWTVEITGLVKRPAKFTMEELISEFPSREFPVTLVCAGNRRKEQNMVKQTIGFNWGSAGVSTSLWKGVPLSEILGRCGIYSRRGGGLNVCFEGAEDLPGGGGSKYGTSIKKEMAMDPARDIILAYMQNGELLTPDHGFPVRIIVPGFIGGRMVKWLKRIIVTPQESDSYYHYKDNRVLPSLVDAELANAEAWWYKPEYIINELNINSVITTPGHQEILPINAFTTQKPYTLKGYAYSGGGKKVTRVEVTLDGGDTWSVCDLDHQEKPNKYGKFWCWCFWSLDVEVLDLLSAKDVAVRAWDESFNTQPDKLIWNLMGMMNNCWFRIKTNVCKPHKGEIGIVFEHPTRPGNQSGGWMAKERQLEISSESNPILKKSVSSPFMNTSAKMYSMSEVRKHNSVESAWIIVHGHIYDCTRFLKDHPGGSDSILINAGTDCTEEFEAIHSDKAKKLLEDYRIGELITTGYDSSPNVSVHGGSTAVSLLAPIKELAPSKNIALVNPREKVPVTLIEKTSISHDVRRFRFALPSEDQQLGLPVGKHIFLCANINDKLCLRAYTPTSTVDAVGHIDLVVKVYFKDVHPRFPNGGLMSQHLDSLPIGSVLNIKGPLGHIEYLGKGNFMVTGKPKFAKKLAMLAGGPGITPIYQVIQSILSDPEDETEMFVVYANRTEDDILVREELEGWANKHKDRLKVWYVVEIAKEGWNYSTGFITEPVLREHVPEGLEGESLALACGPPPMIQFALQPNLEKMGYNVKEDLLIF
What is the function of this protein?
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
What are the official names of this protein?
Nitrate reductase [NADH], clone PBNBR1412, NR.
What is the protein family that this protein belongs to?
Belongs to the nitrate reductase family.
Protein: H3_EMENI
Sequence: MARTKQTARKSTGGKAPRKQLASKAARKAAPSTGGVKKPHRYKPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKSDLRFQSSAIGALQESVEAYLVSLFEDTNLCAIHAKRVTIQSKDIQLARRLRGERS
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: THIM_PSYIN
Sequence: MKKNIDSNIKTIVSALKTLREQKPLVVNISNYVAMNNTANALLALGASPIMAHSRDEMAEMLSFSGALVVNIGTLDSLWIPRMLFAVEQANIHKKTVVLDPVGCGASSLRTATSWQIAEAANKLIIRGNASEIIALAGEKGQSKGVDSLDSSEAALGAARYLRDTYQCAVVISGATDFIVTAGGQIQLNNGHAMMPYVTAMGCTLSALTGAFAAVGEETGLAAAAVLGVAGEIAAEQSKGPGSLQLNLLDALYQLDEATLIQRLKLS
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: SECA2_PEDPA
Sequence: MEFNLDNFRLRKYSKITKKILALGKKYQTLTDDQLRIKTETLRNKLVKGASLDSILIEAYATIREADFRVLGLKPFENQVLGAVVLHYGNVAQMNTGEGKTLTATMPLYLNGLTGPGNFLVTVNSYLANRDAEEIGKVYKWMGLTCASGVSLDDEELDKKAIYQNDIVYTTNSELGFDYLTDNLVDNINKKKLNDLNFALVDEVDSVLLDLAQTPLVISGAPRVQSNLFVSTDRIVKSLKPNVDFEFSEDLKDVWFTQTGIEQLEEYLGIQGLISDKWSDFYRHLVLALKANYVMKRNQDYIVTNREVLLLDSENGRALTGMKLEAGIHQAIEAKEEVELSDQTRSMASITLQNFFKMFRKLSGMTGTAKSSAREFLEVYNLPVLKIPTHKPNIRIDHADVVFATMDEKIEATVRMVKAAYQIKRPVLLKTGSLSLSRLYSRVLLEHGIVHNVLNAQSESKEAMIVASAGKSGAITVATSMAGRGTDIKLGKGVKEKGGLLVIGTERMDSRRVDDQLRGRAGRQGDPGESIFLVSLDDKVVIENAPDWVEKYRLKLEQAVEQGKRKYGAPLKGRRARKIVEKAQQAADSAAEESRKNAVKMDDILRIQRELIYDFRDYIMKSTDLTTMVQQIKNDYFNAIARENKKDAGKLLDFIINNVDYNYMDNDFNPEILESTADIKQYLEEIARNRWSQQQMIVNNKFKQNYLERLAVLKALDVAWIEQVDNLQQLKTVVTSRSSGQHNPVFEYEKEAMHSFEQMKKLFWKNTVKYMLLSELIPGKNGSVRVEFP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: PGK_STRT1
Sequence: MAKLTVKDVELKGKKVLVRVDFNVPVKDGVITNDNRITAALPTIKYILEQGGRAILFSHLGRVKEEADKEGKSLAPVAADLAAKLGQDVKFIPGVTRGAELEAAVNALEDGQVLLVENTRFEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVENPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGMTYTFFKAQGIEIGNSLVEEDKLDVAKALLEKSNGKLILPVDSKEANAFADYTEVKYTEGEAVDPGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQPGVKSIIGGGDSAAAAINLGYADKFSWISTGGGASMELLEGKELPGLAALTEK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROQ_VIBPA
Sequence: MTEKLKNSKEVIAYIAECFPKCFTLEGEAKPLKIGIFQDLAERLNEDEKVSKTQLRAALRQYTSSWRYLHGVKPGAVRVDLDGNPCGELEEEHVEHAKATLAESKAKVQARRKEQAQKAREEGKAKAKPAANKKPQQPRRTNKPKVQKPTKPVETRALNADEITVGNAVNVNMGKGNMAATIVEINKDDVRVQLANGLQMVVKAEHLRA
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBF_BUCAP
Sequence: MKLIRGIHNLKKINSNSAVSIGNFDGVHLGHQKLLSNLYKIGKKNNILTVLILFEPQPLEFLNNKNSPKRLTTIQNKIKYIQSWKIDIILCIKFNESFSSLSAEKFIKNILITKLNIKFIIIGDDFRFGSKRNGNISLLKEIGYQYNFKVIEISSLLYKNKIKISSTNIRKCLLENKIELARKLLGRPFSISGRVIHGNKIGRKLGYPTANISLRKNIPLNNGVYAVKISCFFNKKFVGICNIGIKPSYFSSKKHRLLEVHLFNFNLNLYEEKIEVFLYKKIRNECFFSSKNKLKEQISKDIEIVKKYFNLI
What is the function of this protein?
Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
What are the official names of this protein?
Bifunctional riboflavin kinase/FMN adenylyltransferase, Riboflavin biosynthesis protein RibF.
What is the protein family that this protein belongs to?
Belongs to the RibF family.
Protein: AROQ_MOOTA
Sequence: MKILVINGPNLNLLGNREPETYGRTTLATIEAELRRQASQAGVEIEFFQSNHEGALIDCLHAARGRVDAAVINPGALGHYSIALRDALAAVDYPAVEVHLSNIYRREEFRHHTVTAAVVAGQISGFGPLSYRLGLEAAIELARRRREAPPDGGSNG
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: PUP_MYCGI
Sequence: MAQEQTKRGGGGGEDDDPTGSTAAGQERREKLTEETDDLLDEIDDVLEENAEDFVRAYVQKGGQ
What is the function of this protein?
Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation.  The tagging system is termed pupylation.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein Pup, Bacterial ubiquitin-like modifier.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic ubiquitin-like protein family.
Protein: UREG_ECO57
Sequence: MNIIKQPLRVGVGGPVGSGKTALLEALCKSMRDTWQLAVVTNDIYTREDQRILTEAGALEAERIVGVETGGCPHTAIREDASMNLAAVEALSEKFGNLELIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVGASLEVMERDTLRMRGERPWGFTNLKSGEGLQNIIAFIEEQGMLGK
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_SYNPW
Sequence: MSRVCQLTGTKANNGMAVSHSHIRTKKLQQANLQQRRLWWAEGKRWVNLRITTRALKTIQKKGLGAYAKSLGIDLARL
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ILVC_PROM3
Sequence: MAQLFYDSDADLSLLNGKTVAIVGYGSQGHAHALNLKDSGVDVVVGLYEGSRSAEKARTDGLEVLSVAEASAKADWIMVLLPDEFQKDVYAKEIAPHLSSGKVLSFAHGFNIRFGLIQPPADVDVVMIAPKGPGHTVRWEYQNGQGVPALFAIEQDASGQARALAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSELVKAGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLTAMRDSISNTAEYGDYVSGPRLINADTKAEMKRILADIQDGTFAKNFVAECESGKPEMKKIRDRDAAHPIEQVGKGLRAMFSWLKTA
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: LCL3_ASPFU
Sequence: MRWPPWASDTQAQQQSRKSSSEDDERQAAASSTTTSKKKDWESSVTAIDWAAFTEARTIIPTLILTSGFLGAFYIHRRYLRRFPDAVSITPSYFRRRSLLGQVTSVGDGDNFRIYHTPGGRLAGWGWLPWKKIPTSKKELRDKTVHIRLAGIDAPELAHFGRPEQPFAREAHQWLTSYLFGRRVRAYIHRPDQYQRAVASVYVRRLLDFPPFRRRDVSYEMLKRGLATVYEAKIGAEFGGEAMERKYKKAEWWAKLRGVGLWKDYRRNKTKWESPREYKTRMGLEEAAQPGVEIKK
What are the official names of this protein?
Probable endonuclease lcl3.
What is the protein family that this protein belongs to?
Belongs to the LCL3 family.
What are the subcellular locations of this protein?
Mitochondrion. Membrane; Single- pass membrane protein.
Protein: KSTR2_MYCTU
Sequence: MDRVAGQVNSRRGELLELAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRWYRPGGPLTAQQVGQQYLAIVLGGITKEGV
What is the function of this protein?
Controls the expression of a small regulon that may play a role in the utilization of cholesterol.
What are the official names of this protein?
HTH-type transcriptional repressor KstR2.
Protein: DPGC_STRTO
Sequence: MTTVLPPLEDTDGLWAALTEAAASVEKLLATLPEHGARSSAERAEIAAAHDAARALRVRFLDTHADAVYDRLTDHRRVHLRLAELVEAAATAFPGLVPTQQQLAVERSLPQAAKEGHEIDQGIFLRAVLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGEVEMEAVHLERRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGAANLRLGRFAGPRVSRQVILEGRRIWAKEPEARLLVDEVVEPDELDAAIERSLTRLDGDAVLANRRMLNLADESPDGFRAYMAEFALMQALRLYGHDVIDKVGRFGGRPPA
What is the function of this protein?
Involved in the biosynthesis of the nonproteinogenic amino acid monomer (S)-3,5-dihydroxyphenylglycine (Dpg) responsible of the production of vancomycin and teicoplanin antibiotics.  Catalyzes the unusual conversion 3,5-dihydroxyphenylacetyl-CoA (DPA-CoA) to 3,5-dihydroxyphenylglyoxylate.  DpgC performed a net four-electron oxidation of the benzylic carbon of DPA-CoA and the hydrolysis of the thioester bond to generate free CoA (PubMed:18004875, PubMed:17507985).  DpgC has the ability to process a diverse range of substituted phenylacetyl-CoA substrates (PubMed:18004875).
What are the official names of this protein?
(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: RS14Z_DESAL
Sequence: MARKSLCVKAQRTPKFKVRTYNRCPLCGRPRGYMRKFGICRICFRNMASEGLLPGVIKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SYP_RICCN
Sequence: MLLSKYFLPVLKEEPSEAQVTSHKLMLRSGMIRQQAAGIYTWLPLGLKVLKNIENIVRLNMNKAGALEVLMPCIQPAHLWMESGRFDNYGKEMLKFQDRHDNTLLFGPTNEDMITDIFRHNIKSYKDLPKNLYHIQWKFRDEIRPRFGVMRGREFLMKDAYSFDINEENAVKTYNQMYKAYINAFRDLGVFVIPVIADNGPIGGNLSHEFHIIAETGESTIYYDKKFKTLKDNPDIDVEEIKSWYAAAEEKYEVNKLPISEQEITSSKGIEVGHIFYIGSKYSVNMNALINDEYGKLTPIEMSSYGIGISRLVAAIIEANCDEKGIIWPSSVAPFKVSLINLNIHDSKCVELAEMAYKELSDKNIEVLYDDTEARPGSKFATHDLIGSPHQIIIGPKKAANNIVELKDRKSGVIEDIEVGSLMSVL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_HELHP
Sequence: MNMIKIEPYIPTDISIEEISTNRIRISAYPFESGYAITLAHPIRRLLLSSSVGYAPTALRIQGVTHEFDSIRGIVEDVSHFITNLKNIRFLIKDTESDNVQLHYEFKGPMVLSANELVNDMVGIVNPEAYLATINENASLSFSLIVQKGIGYVPSESIRGKISEDYIPLDAYFTPVKKAVYEIENVLVEDNPNYEKIVFDIETDGQIEPITAFKEAIAIMHKQMSIFGVDLSTASSGTRNISEDSGELKTLMIKIDTLNLSARCFNCLDRSGLKYVGELVIMSENELKNIKNMGKKSYDEIADKLEELGYPVGGEIADDILPLLNRKLAKLKSN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.