PharMolix/UniProtQA huggingface dataset:
Protein: VSPT2_BOTJA
Sequence: VVGGDECNINEHRSLVAIF
What is the function of this protein?
Thrombin-like snake venom serine protease.  Causes the specific clotting of fibrinogen (FGA) with release of fibrinopeptide A.  The aberrant fibrinogen is then incapable of being cross-linked, forming easily dispersible clots.
What are the official names of this protein?
Thrombin-like enzyme TL-BJ 2, SVTLE, Fibrinogen-clotting enzyme TL-BJ isoform 2, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ARGB_ECO8A
Sequence: MNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLND_YERPA
Sequence: MSDNHTEHSLSLTLTPTISEQPALPSTYLDSDIHCPILKQRLDAFQRWQAEAFNSGTSAEVLIAARSDYIDHLLQRLWTFYGFDKVPETALVAVGGYGRGELHPLSDIDVLVLSKQRLNDEQAQRVGQLITLLWDLKLEVGHSVRTLEECLLEGLADLTIATNMIESRLICGDVALFLQMQKHIFSDSFWPSPQFFHAKVVEQQERHKRYHGTSYNLEPDIKSSPGGLRDIHTLLWVARRHFGATSLSEMVDFGFLTNAERNELNESQSFLWRIRFALHLVLTRYDNRLLFDRQLSVAQLLRYEGEGNEPVEHMMKDFYRMTRRVSELNNMLLQLFDEAILALDANEKPRPLDEEFQLRGDLIDLRDENLFVRQPEAIMRMFYLMVRNQDIKGIYSTTVRRLRHARRHLKAPLCHIPEARKLFMAILRHPGAVSRALLPMHRHSVLWAYMPQWGSIVGQMQFDLFHAYTVDEHTIRVLLKIESFADEDTRPRHPLCVELYPRLPQPELLLLAALFHDIAKGRGGDHSILGAHDAVEFAEQHGLNSRESQLVAWLVRCHLLMSVTAQRRDIQDPAVIQQFSAEVQSETRLRYLVSLTVADICATNENLWNSWKQSLLRELYFATEKQLRRGMQNSPDLRERVRHHRLQALALLRMDNIDEEALHRIWSRCRADYFLRHSPNQLAWHARHLLEHDSTKPLVLVSRQATRGGTEIFIWSPDRPSLFAAVVGELDRRNLSVHDAQIFTNRDGMAMDTFIVLEPDGSPLAQDRHPIISHALQQAINRSDYQHPPRVRRLSPKLRHFSVPTEANFLPTHNERRTYLELIALDQPGLLARVGKIFADLGLSLHSARITTIGERVEDLFVLADKDRRALSLETRRELAQRLADTLNPNDKL
What is the function of this protein?
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level.  Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation).  Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.
What are the official names of this protein?
Bifunctional uridylyltransferase/uridylyl-removing enzyme, UTase/UR, Bifunctional [protein-PII] modification enzyme, Bifunctional nitrogen sensor protein.
What is the protein family that this protein belongs to?
Belongs to the GlnD family.
Protein: HSLO_SHEB2
Sequence: MNQDTLHRYLFDNADVRGELVQLQDSYQQVISAQEYPAVLQVLLGELMAATSLLTATLKFSGDISVQLQGNGPVSLAVINGNNLQELRGVARWNAELADDASLTDLFGQGYMVITLTPDEGERYQGVVALDKPTLAACVEEYFNQSEQLPTGIWLFADGKQAAGMFLQILPSKEDHNPDFEHLSQLTSTIKAEELFTLDAESVLHRLYHQEEVRLFDPIDVSFKCTCSHERSAGAIKTLDQAEIEAILAEDGKIEMGCEYCHAKYIFDAIDVAALFANGQTSTTQQ
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_BUCA5
Sequence: MNSLDYNKTNFLKSYSKITDIDIQNGIEIAFIGYSNTGKSSAINALTNQKKLARFSKTPGRTQLINFFEVVSGFRIVDLPGYGYSQAPLLVRSKWQKKVYDYLEKREQIKLFVLLMDIRYPLKKLDQKIISIAVQKKISILVLLTKCDKIKINHQKNQADMVFKKLNVLLDSFEIILFSSYKKIGIEKLKLSLNSSYKKHFILNR
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: HSP90_PODAS
Sequence: MAETFEFQAEISQLLSLIINTVYSNKEIFLRELVSNASDALDKIRYESLSDPSKLDTGKDLRIDIIPDKENKTLTIQDTGIGMTKADLVNNLGTIARSGTKQFMEALTAGADISMIGQFGVGFYSAYLVADRVTVVSKNNDDEQYIWESSAGGTFNISPDNGPSIGRGTKIILHLKDEQTDYLNESKIKEVIKKHSEFISYPIYLHVQKETEVEVPDEEAETVEEGDDKKPKIEEVEDDEEDKEKKPKTKKVKEVKTEEEELNKQKPIWTRNPQDITQEEYAAFYKSLSNDWEDHLAVKHFSVEGQLEFKAILFVPKRAPFDLFETKKTKNNIKLYVRRVFITDDATDLIPEWLSFVKGVVDSEDLPLNLSRETLQQNKIMKVIRKNIVKKALELFTEIAEDKEQFDKFYTAFSKNIKLGIHEDSQNRNTLAKLLRFNSTKSGDEQTSLSDYVTRMPEHQKNMYYITGESIKAVSKSPFLDSLKEKGFEVLFLVDPIDEYAMTQLKEFEGKKLVDITKDFELEETEEEKKQREAEEKEYDGLAKALKNVLGDKVEKVVVSHKLVGAPCAIRTGQFGWSANMERIMKAQALRDTSMSSYMSSKKTFEISPKSPIIKELKQKVEADGENDKTVKSIVQLLFETSLLVSGFTIEEPAGFAERIHKLVALGLNLDEEPEAAADAPAADAGVAAAETSDNAMEEVD
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity).
What are the official names of this protein?
Heat shock protein 90 homolog, Suppressor of vegetative incompatibility MOD-E.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAGJ_PSEAE
Sequence: MADPSFASGRLGSRLQGSIAMIAEELLRAGRLDDALKALQEQVRSQPSNATLRIFLFQLLAVMGQWARAQNQLKVVGELDASALPMVQTYSTAIDCEALRREVFAGRLTPVILGQPAEWIAPLLQALSLDAEGHGEAAQALREQAFDAAPAVPGRIGEAPFAWLADADTRLGPVLEVIVNGRYAWLPMSNLRSLKVEAPSDLRDLVWLPAELTLANGGATVALLPARYAETVEHGDDAARLGRKTEWLDSGLPVGQRLFVTDAGETALFDLRELDFEPTDA
What is the function of this protein?
Component of the H1 type VI (H1-T6SS) secretion system that plays a role in the release of toxins targeting both eukaryotic and prokaryotic species.  Forms a stable complex with TssB1.  This complex, although not crucial for the H1-T6SS function, may fine-tune the assembly of the system (PubMed:22906320).  Plays a role in the interaction between ClpV1 and the TssC1/TssB1 sheath (PubMed:25305017).
What are the official names of this protein?
Type VI secretion system accessory component TagJ.
Protein: YKQ9_SCHPO
Sequence: MTLHCQEPKIRSLDMLSNSEIKPSENSQKTKVLLTKANNASNERAPPPLSHFIAGGVAGMLGAIATAPLDVVKTRLQSDFYKDRFLKQTAKSKSPLTAAYRHFMDTCIILKNVKVHEGTRALFRGLGPNLIGTIPARSINFFSYGNGKRILADLFNNGQENSQIHLMAAAIAGVITSAATNPIWLVKTRLQLDKKSGQAAQYRSSIDCIIKTIRLEGFRGLYKGLSASLLGVGESTLQWVLYEKFKHAVAIRQLRRKELGIQETIYDKVLDWGGKLGGAGIAKFMAAGIAYPHEVVRTRLRQSPSINGTPKYTGLIQCFKLVWMEQGIVGLYGGLTAHLLRVVPNACILFGSYEVIMHFIG
What are the official names of this protein?
Uncharacterized mitochondrial carrier C688.09.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MATK_GRABR
Sequence: MKEFQRYIELDRSWQHNFFYPLIFQEYIYGFAYDPDLKKSILLENAGDKKYSLLIVKRLITRMYQQQNHLILFANHSNQNDFWGHKHTNNLYYQIISEVFAFIVEIPFSLLLISSLESKKRKIVKSHNLRSIHSIFPFFEDKFLHLNYVLEILIPYPIHLEILVQTLRYWMKDASSLHLLRFFLYEYRNWNSLITSQKSISIFSKRNKRLFLFLYNFHVCEYESIFVFFCNQSSHLRSTSFGVLLERIYFYGKLEYLVKVFPFTKDFRLILWLFKEPFPHYVRYRGKSILASKGTSLLMHKWKYYLINFWQCYFSLWSQPTRIYINQLSKHSLDFMGFFSSVQLNSSVVRSQMVENSFLIENTMKKFDTIVRIIPLVGSLAKANFCNVLGHPISKSVWTDLLDSDIIDRFGCICRNLSHYYSGSSRKKTLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSEFLEEFFTEEEKVLSLILPRDSSIARGFYRGPIWYLDIICIHDLANDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: G3P3_NOSS1
Sequence: MKVRVGINGFGRMGRLALRAAWDWPELEFVHINEIKGGAVAAAHLLKFDSVHGRWTPEVEAEGERVLIDGTPLSFSEYGKPDDVPWEDFGVDLVLECSGKFRTPATLDPYFKRGVQKVIVAAPVKEEALNIVMGVNDYLYEPEKHHLLTAASCTTNCLAPVVKVIHEGLGIKHGIITTIHDNTNTQTLVDAPHKDLRRARATSLSLIPTTTGSATAIALIYPELKGKLNGIAVRVPLLNASLTDCVFEVTRPTTVEEINALLKAASEQAPLQGILGYEERPLVSIDYKDDPRSSIIDALSTMVVDETQVKILAWYDNEWGYVNRMVELARKVALSLK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 3, GAPDH 3, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBK97_ARATH
Sequence: MLMSKEDESQMTFSMLPDDLVLNCLARVSKVYYPSLSFVSKKFRSLIASTELQELRSFLGCTSSGLYVCLRFRTNTDYRQICFTLRQKISSSAKILVPISSLDSPFDYRSGVVAVGSDIYAIGGRNLNNSASSKVMVMDCRSHTWREAPSMRVARDDFPSTCVLNGKIYVIGGCKNLDSTNWIEVFDTKTQTWEFLQIPNEEVCRGFNYKIVGYKEAIHVSSLENNRATFMTYEIHKGRWREPHLSLSHGFHFSNCVIENVFYRYSYEMLQWYDSCRKIWKNLKGFVRRSIMNPRGEGVKMVNYGGNIVLLWEECVTIKKKLIWCEEVVIEKKHQGEIWGLLKWSDVVFITDEKNQLVRALAPDV
What are the official names of this protein?
Putative F-box/kelch-repeat protein At4g39290.
Protein: VEXIN_XENLA
Sequence: MIKLHRQSYKNLQNISTASPSRVCKSARGKTSTAQKSHVNKGALSCDVHPHQAQELVSQQVELLHVLHRNDEMWRLAVQDTTKHIQSAEKKASRFSRRKQTAPPKTKSLRTPPACSTDKQNAPTVPASPSSYETLGCREQRPENPKDEATLPLTAHNIPKKAPSLLEKIGLKLKRTVEYIGASNCAFEDD
What is the function of this protein?
Required for neurogenesis in the neural plate and retina.  Cooperates with cell cycle inhibitor cdknx/p27(xic1) to enhance neurogenesis and increase the levels of the neuronal determination factor neurog2/X-ngngr-1 (PubMed:29518376).
What are the official names of this protein?
Vexin.
What is the protein family that this protein belongs to?
Belongs to the vexin family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Note=Nuclear localization is essential for its function in neurogenesis.
Protein: NCAP_NDVB
Sequence: MSSVFDEYEQLLAAQTRPNGAHGGGEKGSTLKVDVPVFTLNSDDPEDRWNFAVFCLRIAVSEDANKPLRQGALISLLCSHSQVMRNHVALAGKQNEATLAVLEIDGFANGMPQFNNRSGVSEERAQRFAMIAGSLPRACSNGTPFVTAGAEDDAPEDITDTLERILSIQAQVWVTVAKAMTAYETADESETRRINKYMQQGRVQKKYILYPVCRSTIQLTIRQSLAVRIFLVSELKRGRNTAGGTSTYYNLVGDVDSYIRNTGLTAFFLTLKYGINTKTSALALSSLSGDIQKMKQLMRLYRMKGDNAPYMTLLGDSDQMSFAPAEYAQLYSFAMGMASVLDKGTGKYQFARDFMSTSFWRLGVEYAQAQGSSINEDMAAELKLTPAARRGLAAAAQRVSEETSSIDMPTQQVGVLTGLSEGGSQALQGGSNRSQGQPEAGDGETQFLDLMRAVANSMREAPNSAQGTPQSGPPPTPGPSQDNDTDWGY
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: Y1542_METJA
Sequence: MVKFMKIKSIAAKNLLSFDDFKITFEDGDVVTIFGPNNVGKTNLFRVLKLLRNIINEKISAVDLEIYLHNKNLKAAKIEVDVIFDKSDKEVIAKFLKIFFKINAPDLIRLCNNLKLNIINSIIDYFSAGSYIWECSELRCYRPYFMLRLRSLEEDIEKIKIYLKERELSEITPDLIDHSKVIHELDRNVEIIEVTNDLKNIITSSVNALITIYEKNEKLFFSTLIDGKENITTRIGDGNIENIVEISMKDFTKDIEKYEDCFKRLTMDKNILRAFVVLLALDKLLANKMSIYVKKVLEYSKENPWDKEIIEDLKYIVRFCGFDYRDIYEISDISLNDILLKIYENSLIFYEDYLPNEGKVMIPDYMIVELLAGLKNNSLEKNVKSKILELFKTSTTKDDLYLGILSMPSEKWIPSYLFYLKNNANLKLRKRYMKIKEMFEYIFNSGSLSFDVILANNKPDIVVYSEDIEIPLNMVGLGVKKILEILTLVFGYESKVILLDTPFNQLYPKYQKRFSKILKDTENIDSQVFIILHSPYFINNENIFNTFRFYKPKKSTKYICIGSIIKDLEKTFGTVILDRTTRKILLSDAVILLSSALRDIPLFDLAEYEDIPIDEYNIEVIRPQNTLSFGKYYALLQYTSIPYILMLRSWILYNLYEEIKDGEGKVRYKLLEKGKYHKIVEERLNFFKNRHPFWISKEEFDKVINIYIKTLEAHREKLIELGYIYLSSKEEVVKYCIEPLRKQLEDILRKKLFIFTVPTDFIIEPQDLKNIQIEKDKYIVHNYIGYRKDVLKEFKEFFDYFVKFHNLQ
What are the official names of this protein?
Uncharacterized protein MJ1542.
Protein: BTUD_ECO7I
Sequence: MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GUAC_BACAH
Sequence: MMENVFDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFKLPVVPANMQTIIDERIATYLAENNYFYIMHRFQPEKRISFIRDMQSRGLIASISVGVKEDEYEFVQQLAAEHLTPEYITIDIAHGHSNAVINMIQHIKKHLPESFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAASKPIIADGGIRTHGDVAKSIRFGATMVMIGSLFAGHEESPGETIEKDGKLYKEYFGSASEFQKGEKKNVEGKKMFVEHKGSLEDTLIEMEQDLQSSISYAGGTKLDSIRTVDYVVVKNSIFNGDKVY
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: YMX1_BRANA
Sequence: MITFFEKLSTFCHNLTPTECKVSVISFFLLAFLLMAHIWLSWFSNNQHCLRTMRHLEKLKIPYEFQYGWLGVKITIKSNVPNDEVTKKVSPIIKGEIEGKEEKKEGKGEIEGKEEKKEGKGEIEGKEEKKEVENGPRK
What is the function of this protein?
May be involved in cytoplasmic male sterility (CMS) by leading to pollen abortion.  Not expressed in fertile (normal) plants.
What are the official names of this protein?
Uncharacterized mitochondrial protein ORF138.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: HEM1_SYNS3
Sequence: MHIAVVGLSHRTAPVEVREKLSIPEQTMEESLQNLRNHEQVLEASILSTCNRLEIYTLVRNPDLGIAAVRDFLSGHSGLESRDLSPHLFTYHHDEAIAHLMRVTAGLDSLVLGEGQILSQVKKMMRLGQEHKSIGPILNRLLTQAVSTGKRVRSETNLSTGAVSVSSAAVELAQLKLGQSRGQDALVTLETEQIAVVGAGRMSRLLLQHLQAKGASGVVLLNRTIERASALATDFPNLPIQCRGLDDLDQCLSTCSLVFTSTAVDDPIIDANRLNALNRRSSLRLIDIGVPRNIASDVHEVSGVESHDVDDLQEVVERNQEARQQVAREAEGLLLEEGRLFLEWWDSLEAVPTINRLRASLEEIRVEELTKALSRMGPDFSARERKVVEALTKGMINKILHTPVTQLRSPQQRSERQQALQVVEKIFDLESGAATQD
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: DMA1_DOTSN
Sequence: MVEIQSQNEHHKFWANHLLPQFRRYIAEIGAYTSKQQDEHVKFFDSLLPHLGPRLPHPHTKAVLTVANMPLGFSVNLSDARKPIARMEIEPLDDTSGSAEDLFAANCIPACFTTLVKGMTTRVDTRWAHQLRQAFTPTSEESAIAKPRLRPGIERVSLAYFGITFDGDNRAMKYCTSHWPKFLGTATAESNDATSADAFLFSAIRRLKPGGEALAPSLDAIQHYFQNERHAKLPSPILFVGLDCIDPSRARIKMYGRTHSTAFSNVRNIMTLGGRALTAETTEFLARLRSIWHLLLNDPKAKDDEDYDRPPLDPNSLRTGLLVSFEVSALVSTPDIKVYVPFWQYHETDVQAINNLEQIFSLLGWDWGSGKYGDLLRKTFVGTDLAATQNHDYVSFNYSKRQGSYMTMYHVPPRPESTTA
What is the function of this protein?
Tryptophan dimethylallyltransferase; part of the hps1-dma1 gene cluster that probably mediates the biosynthesis a derivative of cyclopiazonic acid (CPA) (Probable).  The hybrid polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) nps1 might incorporates acetyl-CoA, malonyl-CoA, and tryptophan (Trp) and utilizes a C-terminal redox-incompetent reductase domain to make and release the tryptophan tetramic acid, cyclo-acetoacetyl-L-tryptophan (c-AATrp), as the first intermediate in the pathway (By similarity).  In addition, the cluster also includes the tryptophan dimethylallyltransferase dma1, the FAD-dependent oxidoreductase toxD, the cytochrome P450 monooxygenase cyp3. 1 and the methyltransferase DOTSEDRAFT_139328; the latter 2 being not present in all CPA-producing fungi but involved in additional modifications that occur in biosynthesis the of a range of CPA and CPA-like products (Probable).  Further studies are required to clarify whether the CPA-like hps1-dma1 cluster is functional or a non-functional relic reflecting evolution of D. septosporum (Probable).
What are the official names of this protein?
Tryptophan dimethylallyltransferase dma1, L-tryptophan dimethylallyl transferase, DMATS.
What is the protein family that this protein belongs to?
Belongs to the tryptophan dimethylallyltransferase family.
Protein: THIG_VESOH
Sequence: MIDIPLVIAKKTYNSRLLVGSGKYKDLNETKLATDMAEADIITVAIRRTNIGQNVNEPNLLDIISPNKYTILPNTAGCYNAKDAIRTCQLARELLGGHNLIKLEILGDKKTLYPNIVETLSAAKTLVDNGFDVMVYTSDDPIVAKELENIGCVAIMPLASLIGSGQGITNPTQIKLIKEHATVPVLIDAGIGCASDAAKAMELGCDGVLMNSAIANANNPILMASAMKNAIIAGRESFLSGRMMKKSYASASSPMVDLI
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPB_NOSP7
Sequence: MTNQAPIPVIVNGAAGKMGREVIKAVAQAPDLNLVGAIDHSLEHQDKDAGELAGLSEPLEVPITNQLEPMLGYVAGDRQSPPGVIVDFTHPDSVYDNIRSAIAYGIRPVVGTTGLSPEQIQDLADFADKASTGCLIIPNFSIGMVLLQQAAIAASKYFDHVEIIELHHNQKADAPSGTAIQTAQLLGELGKTFNPALVEETEKLPGARGSIADEGIRIHSVRLPGLIAHQEVIFGAAGQIYTLRHDTSDRACYMPGVLLAIRKVLALKSLVYGLEKIL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KDPA_LISMH
Sequence: MKYIVMQDVFFVVLLLVLAVPLGIYMYKVMIGEKVFLSRVLEPVERFGYRLMGVSEVGMSAKRYAVSVLAFSAVGFVFVMAVLMLQGFLPLNPEGMKGLSFSLAFNTAASFVSNTNWQAYSGETALSYFSQSIGLTVQNFVSAATGIAVLFAVIRGFIWKKQKTVGNFWQDLFRVTLYILLPLSLVLALLLVSQGVVQSFADYSVVETLENGAKQLIPLGPAASQIAIKQLGTNGGGFFGANSAFPFENPSSFTNLIEMLAILLIPVALVVMFGRAVKDSKQGRAIMTAMMIVFVIGVVAITISEQFAGPHYQGVATSGSMEGKEVRFGVGGSSLFAASTTAASNGAVNAMHDSLTPLGGLVPMFFMQLGEVIFGGVGSGLYGMIGFIILTVFIAGLLVGRTPEYLGKKIEPYDMKMVCLLILVPPLLTLFGTAVAVMMPSVQASVSASGAHGFSEVLYAFTSMGNNNGSAFAGFAADTTFTNMVGAVMMLLARFIPLVAALYLAQNMAGKSSVAASSGTLSTKNGMFIGLLIGVVVLVGALSFLPALALGPIADFFTTFK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUSB_CHLPN
Sequence: MATLSPEKFSGSPISISKEFPQQKMREIILQMLYALDMAPSAEDSLVPLLMSQTAVSQKHVLVALNQTKSILEKSQELDLIIGNALKNKSFDSLDLVEKNVLRLTLFEHFYSPPINKAILIAEAIRLVKKFSYSEACPFIQAILNDIFTDSSLNENSLSI
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: SCAM6_ORYSJ
Sequence: MHHDPNPFDEGNADDNPFSNGGGGGGGGGSRQQYGFRPTEPAGFGAGRGDATVDVPLDTMGDSKSKARELSSWETDLKRREADIKRREEALRNAGVPMEDKNWPPFFPIIHHDIANEIPANLQKLQYLAFASWLGIVLCLSWNFIAVIVCWIKEGDSKLFFLATIYALLGIPLSYLIWYRPLYRAMRTNSAFSFGWFFLCYLIHIGFCIIAAIAPPIVFHGKSLTGILAAIDTFSEHVIIGIFYFVGFALFCLETLLSIGVLQRVYMYFRGNK
What is the function of this protein?
Probably involved in membrane trafficking.
What are the official names of this protein?
Secretory carrier-associated membrane protein 6, Secretory carrier membrane protein 6.
What is the protein family that this protein belongs to?
Belongs to the SCAMP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein.
Protein: RECA_BRUA4
Sequence: MSQNSLRLVEENSVDKTKALDAALSQIERAFGKGSIMRLGKNAPVIEIETVPTGSLSLDIALGVGGLPKGRIVEIYGPESSGKTTLALHTIAEAQKKGGICAFVDAEHALDPVYARKLGVDLENLLISQPDTGEQALEITDTLVRSGAIDVLVVDSVAALTPRAEIEGEMGDSLPGLQARLMSQALRKLTASISRSNCMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSIKERDEVVGNQTRVKVVKNKLAPPFKQVEFDIMYGAGVSKTGELVDLGVKAGVVEKSGAWFSYNSQRLGQGRENAKQYLKDNPEVAREIETTLRQNAGLIAEQFLEDGGPEDDAGDAAEM
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYGB_ECOLC
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLDAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFTEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.