PharMolix/UniProtQA huggingface dataset:
Protein: MSCL_CUPNH
Sequence: MGMISEFRTFAVRGNVIDLAVGVIIGAAFGKIVDSVVNDLIMPLVGRVIGKLDFSSMFIVLADPPPGTPTTLDALKKAGVPVFAYGNFLTIVVNFLILAFIIFLMVRAFNRMRAAEPEAAPAAPPEEVVLLREIRDSLKTR
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PQQD_RHOPA
Sequence: MAPRRISVSETCRPVLPRHARLKFDDTRQRWVILAPERVLAPDEIAVEILQLCDGACDVAAIIDALAAKYTADRAEIGRDVMAMLQDLADKGFLTEARETAP
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.
Protein: ROT_STAAM
Sequence: MHKLAHTSFGIVGMFVNTCMVAKYVIINWEMFSMKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILLTLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQQEKVELLNFISDAIASRATAMQNSLNAIIAV
What is the function of this protein?
Global regulator with both positive and negative effects that mediates modulation of several genes involved in virulence.  Also, modulates the expression of genes not previously implicated in pathogenesis (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator rot, Repressor of toxins.
What is the protein family that this protein belongs to?
Belongs to the rot family.
Protein: SIGI_BACSU
Sequence: MKPVLSLLFKLGKKKQTLEKAVESIQKGNKDLQNELIQQYKPFIAKTVSSVCKRYIDEKDDEFSIGLIAFNEAIEKYSPEKGNSLLAFAELIIKRKVIDYIRKEARSAQNINIDLQEGDDQESSQSLIEAELSIDEYRRQIEQEQRREEILYFQKQLKDYGLSFKELLENSPKHTDARQNAIKVAMTLVEHEELAAILYTKKQLPVKQLEQLVSVSRKTIERNRKYIIAMCIIITGDYIYLKDYLKGVLHS
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is involved in regulation of cell wall metabolism in response to heat stress.  Acts by regulating the expression of genes such as bcrC, mreBH and lytE (PubMed:18156261, PubMed:21541672, PubMed:23199363).  Also plays a role in survival at low temperatures (PubMed:19114499).
What are the official names of this protein?
RNA polymerase sigma factor SigI.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. SigI subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSPH2_CLOB1
Sequence: MKSERAKQIIDSKKYIPVYYKNTPVHIEKVDNKENIAHIKSLNTDKEIVVNVKTLSECNKLNN
What are the official names of this protein?
Small, acid-soluble spore protein H 2, SASP H 2.
What is the protein family that this protein belongs to?
Belongs to the SspH family.
What are the subcellular locations of this protein?
Spore core.
Protein: URE1_RHOJR
Sequence: MTELSRARYAELFGPTTGDRIRLADTDLLIEITEDRSGGPGLAGDEAVFGGGKVLRESMGQGRATRAEGAPDTVITGVVVVDHWGIIKADVGIRDGRIVALGKAGNPDTMSGVHPDLVVGPSTEIIAGNGKILTAGGIDCHVHFICPQIMDEALGGGITTMIGGGTGPAEGSKATTVTPGSWHTARMLEALDGWPMNIALLGKGNTVSSESMWEQLRGGVSGFKLHEDWGSTPAAIDACLTVADAAGVQVALHSDTLNEAGFVEDTLAAIAGRAIHAYHTEGAGGGHAPDIITVAAHANVLPSSTNPTRPHTVNTLDEHLDMLMVCHHLSPKIPEDLAFAESRIRPSTIAAEDLLHDLGAISMIGSDSQAMGRIGEVVLRTWQTAHVMKRRRGFLAGDNGADNQRVQRYVAKYTICPAVAHGLEAEIGSVEVGKLADLVLWDPAFFGVRPHAVIKGGMIAWAAMGDANASIPTPQPVLPRPMFGAAPKAAAATSVHFVAPHALEDGLADRLDLSRRLVPVANVRSRGKSDMPRNDAQPRIEVDPDTFTVRIDGDVWEEQPAAELPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PETL_TUPAK
Sequence: MVTLISYISLLAGFVIIASVFYLALVKIKLI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 6, Cytochrome b6-f complex subunit PetL, Cytochrome b6-f complex subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PetL family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RS4_METST
Sequence: MGHPKKPRKQYDTPSHPWNADRIKEENRLANKYGLKNKKEIWKAESRVKRYRRDARIILGMDIDERADKEKELLDHLVRAGFISPNAKLEEVLDLNVEDILRRRLQSLVFKRGLSHTAKEARLFVVHGHITLNGKKINAPGHLVEKADEENIDFYPGSSVAKQFETQETEEVAAEEEPKDEE
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CEP76_XENLA
Sequence: MALPPEKATELKQIIHEQLTRMDVHGKIREVLAESLREEFQTESQQLSEEDLMQALRQRGIVDEVMKELHFMEDRHTRELTSTPKPATHYIDKETRSLRKTNVDPTRRYLHLQVLNGKAFLEHLQESDPLPGQACSTFTLCLHFRNQRFRSKPVPCACEPDFQDGFLLEVHKDSLGDGSKMADATTMLSICDPVQLVLLKTDTSGETTLVSSHFLEWRSILGTEKGVTSLAVELLGVGSECKVSVGVLNVKLELYPPLNKTLSQEVINTQLTLERQKTAEKERLFLVYAKQWWREYLQIRPSHNSRLVKIFAQDENWVNRPVCSYIRPLRAGRLLDTPRQAARFVNVLGYERAPTVGGGGKPEQWCTLLAFLCRNKGDCEDHCNLLCCLLLGFGLDAYVCVGTKGRGQAHTWVMTCGADGAITFWESLTGHRYVHKPINPDDPPMVEQPKPLYPYKTIGCVFSHKRFLANSQPLDAVEVCVFDLHDESRWKPMSEEAIKSVCSPGSLASLPPFPPLCSSLLDAATESNEIELQLRLLVLEHRKDLDLTTVWDDQLSYLLSPALASYEIERTTGISAGNEEFQDSIRRAVPDGHTFKGFPIHFVHRNARRAFATCLRSPFCDEIISCRGDQMRLAVRVRVYTYPEAACAVWIMFACKYRCVL
What is the function of this protein?
Centrosomal protein involved in regulation of centriole duplication.  Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication (By similarity).
What are the official names of this protein?
Centrosomal protein of 76 kDa, Cep76.
What is the protein family that this protein belongs to?
Belongs to the CEP76 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Does not localize along the ciliary axoneme.
Protein: SURE_RUBGI
Sequence: MRILIANDDGYLAPGIAALVKACEGLGTIDVIAPEQNASGTSNALTLNRPLSVFEARGEPVQGFRVVNGTPSDSVHVALTGLLPHKPDLVLSGINQGANMGDDTLYSGTVAAAMEGYLFGVPAIAFSQAEKGWTHLDAAAATARAIVEQVLAGGPPTGPWLLNVNIPNRADAASLPRLVTRLGRRHASEPVIRQTNPRGEPIYWIGPAGDARDAGEGTDFHAVAHGAVSITPLQVDLTDHAMRGAWASRLGVPLA
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18_PECCP
Sequence: MDKKAARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAASTVEKAIAEQLKSTGNKDAASAIGKAIAERALEKGIKDVSFDRSGFQYHGRVQALADAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CLPP_BACTN
Sequence: MDDFRKYATKHLGMNGMVLDDVIKSQAGYLNPYILEERQLNVTQLDVFSRLMMDRIIFLGTQVDDYTANTLQAQLLYLDSVDPGKDISIYINSPGGSVYAGLGIYDTMQFISSDVATICTGMAASMAAVLLVAGAEGKRSALPHSRVMIHQPMGGAQGQASDIEITAREIQKLKKELYTIIADHSHTDFDKVWADSDRDYWMTAQEAKEYGMIDEVLIKK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLR9_PIG
Sequence: MGPRCTLHPLSLLVQVTALAAALAQGRLPAFLPCELQPHGLVNCNWLFLKSVPHFSAAAPRANVTSLSLLSNRIHHLHDSDFVHLSSLRTLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNSITTVPALPDSLVSLSLSRTNILVLDPTHLTGLHALRYLYMDGNCYYKNPCQGALEVVPGALLGLGNLTHLSLKYNNLTEVPRSLPPSLETLLLSYNHIVTLTPEDLANLTALRVLDVGGNCRRCDHARNPCRECPKDHPKLHSDTFSHLSRLEGLVLKDSSLYNLDTRWFRGLDRLQVLDLSENFLYDCITKTTAFQGLARLRSLNLSFNYHKKVSFAHLHLAPSFGHLRSLKELDMHGIFFRSLSETTLQPLVQLPMLQTLRLQMNFINQAQLSIFGAFPGLLYVDLSDNRISGAARPVAITREVDGRERVWLPSRNLAPRPLDTLRSEDFMPNCKAFSFTLDLSRNNLVTIQSEMFARLSRLECLRLSHNSISQAVNGSQFVPLTSLRVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFTMQGVGHNLSFVAQLPALRYLSLAHNDIHSRVSQQLCSASLCALDFSGNDLSRMWAEGDLYLRFFQGLRSLVWLDLSQNHLHTLLPRALDNLPKSLKHLHLRDNNLAFFNWSSLTLLPKLETLDLAGNQLKALSNGSLPSGTQLRRLDLSGNSIGFVNPGFFALAKQLEELNLSANALKTVEPSWFGSMVGNLKVLDVSANPLHCACGATFVGFLLEVQAAVPGLPSRVKCGSPGQLQGHSIFAQDLRLCLDETLSWNCFGISLLAMALGLVVPMLHHLCGWDLWYCFHLCLAWLPHRGQRRGADALFYDAFVVFDKAQSAVADWVYNELRVQLEERRGRRALRLCLEERDWLPGKTLFENLWASVYSSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILRPDAYRSRYVRLRQRLCRQSVLLWPHQPRGQGSFWAQLGTALTRDNHHFYNRNFCRGPTTAE
What is the function of this protein?
Key component of innate and adaptive immunity.  TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms.  TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity).
What are the official names of this protein?
Toll-like receptor 9.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle, phagosome. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. Exit from the ER requires UNC93B1. Endolysosomal localization is required for proteolytic cleavage and subsequent activation. Intracellular localization of the active receptor may prevent from responding to self nucleic acid.
Protein: HIS7A_WHEAT
Sequence: MTTAPFVSPSLPRLHSARASPFPKPSVGSGGGVAFPARTYGSSLRLRSAVMSASGVGGNGSPMAPEESTVSSRLGEVKRVTKETNVHVKINLDGTGVANSSTGIPFLDHMLDQLASHGLFDVYVKATGDTHIDDHHSNEDIALAIGTALLQALGDRKGINRFGHFTAPLDEAAVEVILDLSGRPHLSCGLSIPTERVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGNNSHHIIEATFKAFARALRQATEYDLRRQGTIPSSKGVLSRS
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase 1, chloroplastic, IGPD 1.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CUTC_VIBA3
Sequence: MNTEIEVCIDNLESLYNALSGGANRIELCSSLALGGLTPSFGMMKQAAKISSVPVYAMIRPRQGDFIFDYDDILCMLEDIEACARAGVNGVVLGVLTPDGEIDMSAMQILSSKAHQLKLAITFHRAIDQLQDYKVPLEQIIELGCERILTSGLAINAEQGINVLADMVKQADGRIDIMAGAGVNATNAKMIQSTTQVPALHLSGKSTRPSLMESNSSAQMGSNDVDDYQIPVTDANKISNVRAALTA
What are the official names of this protein?
PF03932 family protein CutC.
What is the protein family that this protein belongs to?
Belongs to the CutC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS8_MYCLE
Sequence: MNVPEPTLDDLPLRDNLRGKSPYGAMQLLVPVLLNTNENPHPPTKALVDDVVRSVQKVAVDLHRYPDRDAVALRQDLASYLTAQTGIRLGVENIWAANGSNEILQQLLQAFGGPGRSAIGFVPSYSMHPIIADGTHTEWLETVRADDFSLDVEAAVTAVADRKPDVVFIASPNNPSGQSISLADLRRLLDVVPGILIVDEAYGEFSSRPSAVALVGEYPTKIVVTRTTSKAFAFAGGRLGYLIATPALVEAMLLVRLPYHLSSVTQAAARAALRHADDTLGSVAALIAERERVTKSLVHMGFRVIPSDANFVLFGHFSDAAGAWQHYLDTGVLIRDVGIPGYLRATTGLAEENDAFLKASSEIAATELAPATTLGAS
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: TCPZ_HUMAN
Sequence: MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444).  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444).  The TRiC complex plays a role in the folding of actin and tubulin (Probable).
What are the official names of this protein?
T-complex protein 1 subunit zeta, TCP-1-zeta, Acute morphine dependence-related protein 2, CCT-zeta-1, HTR3, Tcp20.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU4LM_VAMBR
Sequence: MSLTYMNMFMAFTISLLGLLMYRAHMMSSLLCLEGMMLSLFVMMTMTILNTHLTLASMIPIILLVFAACEAALGLSLLVMVSTTYGMDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CACO1_BOVIN
Sequence: MEESSLSRAPSRGGVNFLNVARTYIPNTKVECHYTLPPGTVPSASDWIGIFKVEAACVRDYHTFVWSLVPESVTDGSPIHASVQFQASYLPKPGAQLYQFRYVNRQGRVCGQSPPFQFREPRPMDELVTLEETDGGSDILLVVPKATVLQNQLDESQQERNDLMQLKLQLEGQVTELKSQVQELEKALAAARQEHAELAEQYKGLSRSHGELTEERDILSRQQGDHVARILELEEDIQTISEKVLMKEVELDRVRDSVKALTREQEKLLGQLKEVQADKEQSEAELQMAQQENRRLNLELQEAKDRQEEQSAQAQRLKDKVAQMKDTLGQVQQRVAELEPLKEQLRGAQELAASSQQKAALLGEELASAAGARDRTIAELHRSRLEVAGVNGRLAELSLHLKEEKSQWSKERAGLLQSVEAEKDKILKLSAEILRLEKAVQEEKTQSQVFKTELAREKDSSLVQLSESKRELTELRSALRVLQKEKEQLQEEKQELLEYMRKLEARLEKVADEKWSEDPATEDEEAAVGLSCPAALTDSEDESPEDMRLPPYSLCESGDSGSSPATGPREASPLVVISQPAPIAPQLSGPAEDSSSDSEAEDEKSVLMAAVQSGGEEANLLLPELGSAFYDMASGFAVGPLTEASTGGPATPPWKECPICKERFPVHTQTHTYTHTHTHA
What is the function of this protein?
Seems to enhance inorganic pyrophosphatase thus activating phosphogluomutase (PMG).  Probably functions as component of the calphoglin complex, which is involved in linking cellular metabolism (phosphate and glucose metabolism) with other core functions including protein synthesis and degradation, calcium signaling and cell growth (By similarity).
What are the official names of this protein?
Calcium-binding and coiled-coil domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the CALCOCO family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Shuttles between nucleus and cytoplasm.
Protein: DCP1_CAEEL
Sequence: MSDAKKKAAAELAAKNLAQLQKIDIAASKILDKMPFAAIYHIDAARKEWNQSNCEGTFFVYQRADRPYFSFLIANRNDPSDFIEPLTLNHILRHDGNFIYFYKDLASIQALWFHQIDDAQKIYNLLQKLVNRLKGSTTEQARAAKAASEAPQASVPAPTQAPAAPAQAPQMAPQAPPKVDLLQLIKSAQNPPQKSAATIEQMPPMLQKLMLKEPGAAMSADELEKDLIKSAKPHRNHLLQEFTNSTSAISLAAVSTKPLHGSEGDVESDIAEGEILEPLDASFVVGSGEQTPVLNKEQFISAIAHLMQTDDEFVSQIHQAYVSALNRRLNID
What is the function of this protein?
Component of the decapping complex necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay (By similarity).  In contrast to orthologs, does not possess decapping activity and does not remove the 7-methyl guanine cap structure from mRNA molecules (PubMed:16199859).  In the nervous system, negatively regulates the expression of insulin-like peptide ins-7, which in turn promotes longevity (PubMed:32366357).  This may in part be through promoting the activity of daf-16 in distal tissues (PubMed:32366357).  Required for the developmental axon guidance and regrowth of PLM touch receptor neurons (PubMed:31983639).  In ADL sensory neurons, plays a role in ciliary shape formation (PubMed:28887031).  Acts in neurons to promote larval survival at high temperatures by negatively regulating lin-14 expression (PubMed:28250105) (Probable).
What are the official names of this protein?
mRNA-decapping enzyme 1.
What is the protein family that this protein belongs to?
Belongs to the DCP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule. Note=Diffusely localized in the cytoplasm, but accumulates in puncta during pronuclear migration in embryos (PubMed:16267265). After pronuclear migration, accumulates in P-granules which segregated to the posterior cell, and smaller puncta scattered in the cytoplasm (PubMed:16267265). Localizes to cytoplasmic puncta in neuronal cell bodies of neurons such as touch receptor neurons (PubMed:31983639). In some cytoplasmic puncta in touch receptor neurons, co-localizes with car-1 (PubMed:31983639).
Protein: NUOD_PARUW
Sequence: MTKVSKERLKELEESGDVMELNLGPQHPSTHGVLRLKLRLEGEVVLSCDPVIGYLHTGVEKECESRTYHQVFTLVDRLDYLSGPAEEQAFAGALERLMNIEVPERAQTIRIILLELSRIASHLLWAGTSALELNMSSVFMYSFAEREKILDLFEQVSGARMFPSLWRIGGLAKDLNSDFISHLKEFISGFQKIWKELDRLLTDNFVWCKRLQGVAVIDQEICKQYMCTGPVLRASGISYDIRKAYPYLGYENYNFDIPTHIDGDSYARYLVRMEEMLQSISIIEQAIARLKPGVVLTNDRKVALPPRKELARSMEAVIHQFKLISEGLHPPVGSVYNCVESARGELGHYVISDGTPKPYRLRVRSPSFSHVEVLKKVLRGHVISDVVVAIASVDPILGDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DCE_DROME
Sequence: MSLNPNGYKLSERTGKLTAYDLMPTTVTAGPETREFLLKVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLDLDVPDRALPLQQLIEDCATTLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTATANTNMFTYEIAPVFILMENVVLTKMREIIGWSGGDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVMFTSDQCHYSIKSCAAVCGLGTDHCIVVPSDEHGKMITSELERLILERKAKGDIPFFVNATAGTTVLGAFDDINTIADICQKYNCWMHIDAAWGGGLLMSRKHRHPRFTGVERADSVTWNPHKLMGALLQCSTIHFKEDGLLISCNQMSAEYLFMTDKQYDISYDTGDKVIQCGRHNDIFKLWLQWRAKGTEGFEQQQDRLMELVQYQLKRIREQSDRFHLILEPECVNVSFWYVPKRLRGVPHDAKKEVELGKICPIIKGRMMQKGTLMVGYQPDDRRPNFFRSIISSAAVNEADVDFMLDEIHRLGDDL
What is the function of this protein?
Catalyzes the production of GABA.
What are the official names of this protein?
Glutamate decarboxylase, GAD.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family.
Protein: RS5_THET8
Sequence: MPETDFEEKMILIRRTARMQAGGRRFRFGALVVVGDRQGRVGLGFGKAPEVPLAVQKAGYYARRNMVEVPLQNGTIPHEIEVEFGASKIVLKPAAPGTGVIAGAVPRAILELAGVTDILTKELGSRNPINIAYATMEALRQLRTKADVERLRKGEAHAQAQG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: KHSE_CALBD
Sequence: MISVKVPASSANLGAGFDCMGVALKLYNIIEVEEIEKGLIITSSPDDPSIAKDENNLVFRAMKTVFDEVGWYPRGLRINLINEIPLTRGLGSSAACISGGIYAANLLCGGKLSEEEMIYLAAKMEGHPDNSTPAMIGGLVFAVLEDKKVNYIKFVVPARLKFAVFIPDFQLSTEYARNILPKYIEFKDAVFNIGRATLFASAITTGNYELLPAATQDRLHQPYRKKLIPDFDKIVNLSLEAGAKGAFLSGAGPSIIALVDENYEIFEQNVKNALASMDLVANWDFMILEADNSGATVFSVQSTSLKR
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_STAAE
Sequence: MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: AROB_ALKOO
Sequence: MLETKINLGKVTYPLYMGRNLLDNLDVLIEDHIEGKTVFLLTEDNVFKYYGNPLLEKLKSSRFKYHIIESGETSKSIDTYGEIIHELTENKQDRDTIILALGGGVIGDLGGFVASTYMRGVDLIHIPTTLLAQIDSSIGGKTGINFGAIKNLLGTFYHPRAVYMDLSTLDTLPKREYIAAFGEIIKYGLIGDYDLLLDLDQHHRAYLDRTRSVDDLILKCIRMKENIVLKDERDSGMRQVLNLGHTFAHGLESSTNFQKFLHGEAVALGLIFASNLSLKLKFIAEEYHQFVNQLIYKYFSDRYILQLDTEGIVEAMTMDKKNKEHRITFILPVDKEKVEIFKNIPIEIVEESLEEIKYGFRCK
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELT4_CAEEL
Sequence: MDNNYLDASHRKRLVCSNCNGTNTTLWRRKAEGDPVCNACGLYFKLHHVTRPIPMKKNKKHAVLPAPGISKL
What is the function of this protein?
Probable transcription factor (PubMed:20938051, PubMed:24834345).  Plays a role in regulating heme-dependent expression of heme transporter hrg-1 (PubMed:20938051).  Modulates lifespan in a daf-16-dependent manner (PubMed:24834345).
What are the official names of this protein?
Probable transcription factor elt-4, GATA-type domain-containing protein elt-4.
What are the subcellular locations of this protein?
Nucleus.
Protein: FLIE2_BRADU
Sequence: MLEAISSTAISAGQAASRATETQAIAPAAPTAIQSGGDVGFDSVMKQVTTDAIGTLKAGEAASISAMQGKESTRRVVEALMSAEQALQTAVAVRDKVVQAYQEVVRMSI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE 2.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.