PharMolix/UniProtQA huggingface dataset:
Protein: UNG_BACC3
Sequence: MKHVLKNDWGPLLAPEFEKEYYRELDVFLKEEYSIHVVYPKIEDIFNALEYTSYENTKVVILGQDPYHGPNQAHGLSFSVQPGVKTPPSLLNMYKELRDEYGYDIPNNGYLVKWAEQGVLLLNTVLTVRQGEANSHKGKGWEHFTDRVIELLNEREKPVIFILWGRHAQAKKKLITNSNHHIIESVHPSPLSARRGFFGSKPYSKVNTILANMGEREIDWEIPNL
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZAPC_MUSP7
Sequence: MKLIPDDNWRWYFDADQARLMLDLANGMTFRSRFSATMLTPDAFNPSDFCVEDAALFFTYQEKCLTLNIDAQAKAELVLNALVANRFLKPLMPKSWHFAALGHGEYCPQLGELVWVRLNERLEDACFMVVDTGDKASLCLLAQAELALSGKVMVLGEAIKIMHDRLCPVDEGADHAQSSLHFAHAG
What is the function of this protein?
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ.  Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
What are the official names of this protein?
Cell division protein ZapC.
What is the protein family that this protein belongs to?
Belongs to the ZapC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYL_STRMK
Sequence: MTSAETNAYDPQQVESAAQKYWDATRAFEVDETSDKPKYYCLSMLPYPSGALHMGHVRNYTIGDVISRYKRMTGHNVLQPMGWDAFGLPAENAAIKNKTAPAAWTYKNIEHMRGQFKAMGYAVDWSREFATCRPDYYVHEQRMFTRLMRKGLAYRRNAVVNWDPVDQTVLANEQVIDGRGWRSGALVEKREIPQWFLRITDYAQELLDGLDELDGWPDSVKTMQRNWIGRSEGLEIQFDVRDVDGTALDPLRVFTTRPDTVMGVTFVSIAAEHPLALHAAKNNPELAALLSEMKQGGVSEAELETQEKRGMDTGLRAIHPVTGEKVPVWVANFVLMGYGTGAVMAVPGHDQRDNEVANKYGLPIKQVIALKDPRNDDERTWDGARWQDWYSDKNRAFELVNSAEFDGLDFQGAFEALAERFERKAQGQRRVNYRLRDWGVSRQRYWGCPIPVIYCDKCGAVPVPEEQLPVVLPEDVAFSGTGSPIKTDPEWRKTTCPECGGAAERETDTFDTFMESSWYYARYTSPGARDAVDKRGNYWLPVDQYIGGIEHAILHLMYFRFYHKLLRDARMVDSNEPARNLLCQGMVIAETYYRPNPDGSKDWINPADVEVQRDERGRITGATLIADGQPVVVGGTEKMSKSKNNGVDPQAMVDKYGADTVRLFSMFAAPPEQSLEWNEAGVDGMARFLRRLWAQVQKHAADGAAPALDVAALDANQKALRRKTHETIGKVGDDYGRRHSFNTAIAAVMELMNALAKFEDGSEQGRAVRQEALQAIVLLLNPITPHASHALWQVLGHGETLLEDQPFPQADAGALVRDALTLAVQVNGKLRGTIEVAADAAREQVEALALAEPNAAKFMEGLTVRKIIIVPGKIVNIVAA
What are the official names of this protein?
Leucine--tRNA ligase, Leucyl-tRNA synthetase, LeuRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM_ESCF3
Sequence: MSDWTPSLYLHFAAERSRPAVELLARVPLENIEYVADLGCGPGNSTALLHHRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPKQALDLIFANASLQWLPDHYELFPHLVSLLSPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQHFLTRYHQMLEEQYPLQENGQILLAFPRLFIVARRTE
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CBIN_SALPC
Sequence: MKKTLMLLAMVVALVILPFFINHGGEYGGSDGEAESQIQALAPQYKPWFQPLYEPASGEIESLLFTLQGSLGAAVIFYILGYCKGKQRRDDRA
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PERF_MOUSE
Sequence: MATCLFLLGLFLLLPRPVPAPCYTATRSECKQKHKFVPGVWMAGEGMDVTTLRRSGSFPVNTQRFLRPDRTCTLCKNSLMRDATQRLPVAITHWRPHSSHCQRNVAAAKVHSTEGVAREAAANINNDWRVGLDVNPRPEANMRASVAGSHSKVANFAAEKTYQDQYNFNSDTVECRMYSFRLVQKPPLHLDFKKALRALPRNFNSSTEHAYHRLISSYGTHFITAVDLGGRISVLTALRTCQLTLNGLTADEVGDCLNVEAQVSIGAQASVSSEYKACEEKKKQHKMATSFHQTYRERHVEVLGGPLDSTHDLLFGNQATPEQFSTWTASLPSNPGLVDYSLEPLHTLLEEQNPKREALRQAISHYIMSRARWQNCSRPCRSGQHKSSHDSCQCECQDSKVTNQDCCPRQRGLAHLVVSNFRAEHLWGDYTTATDAYLKVFFGGQEFRTGVVWNNNNPRWTDKMDFENVLLSTGGPLRVQVWDADYGWDDDLLGSCDRSPHSGFHEVTCELNHGRVKFSYHAKCLPHLTGGTCLEYAPQGLLGDPPGNRSGAVW
What is the function of this protein?
Pore-forming protein that plays a key role in granzyme-mediated programmed cell death, and in defense against virus-infected or neoplastic cells (PubMed:19446473, PubMed:21037563, PubMed:3261391, PubMed:7526382, PubMed:8164737, PubMed:26306037, PubMed:35148176, PubMed:35705808).  Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores (PubMed:19446473, PubMed:21037563, PubMed:3261391, PubMed:7526382, PubMed:8164737, PubMed:26306037, PubMed:35148176, PubMed:35705808).  Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes (PubMed:19446473, PubMed:21037563, PubMed:3261391, PubMed:7526382, PubMed:8164737, PubMed:26306037, PubMed:35148176).  Perforin pores allow the release of mature caspase-7 (CASP7) into the extracellular milieu (PubMed:35705808).
What are the official names of this protein?
Perforin-1, P1, Cytolysin, Lymphocyte pore-forming protein.
What is the protein family that this protein belongs to?
Belongs to the complement C6/C7/C8/C9 family.
What are the subcellular locations of this protein?
Cytolytic granule. Secreted. Cell membrane; Multi-pass membrane protein. Endosome lumen. Note=Stored in cytolytic granules of cytolytic T-lymphocytes and secreted into the cleft between T- lymphocyte and target cell (PubMed:2040805, PubMed:8164737). May be taken up via endocytosis involving clathrin-coated vesicles and accumulate in a first time in large early endosomes (By similarity). Inserts into the cell membrane of target cells and forms pores. Membrane insertion and pore formation requires a major conformation change (PubMed:19446473, PubMed:21037563).
Protein: NU2M_VARBA
Sequence: MNPIINFILLFSMMAGTILAMTSHHWVYAWLGLELNTLAIIPIISKTHHPRATEASTKYFLIQAISSALFLLSGITNAYLYGTWDINHLSNNFSKILLTIALATKLGLAPVHFWLPEVLQGVPILTALIIATWQKVAPMALLIMTWNLIPTPITLTMGLLSTIIGGLGGLNQTPLRKMMAYSSIAHLGWMVIIITIAPNLTLLNLTLYMIFTSSAMLTMHLTISKTLQNAMHISHHSPIITSLFLLSLLSLGGLPPMSGFSPKWLILQELTLHHLTPLALSMALMALLSLMFYLRATYISTMTLSPSIITLKTTWRLKSVSTTSSLSMLTPPSLLILPIMPLLIQ
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ENGB_UREPA
Sequence: MAKFIKSAHYFDQYPIDKQFEICVIGRSNVGKSSLINALANKKIARTSNTPGRTQLVNFFDFNNFRLVDLPGYGFAKVSKEKQTDLAAIIDQYLGYRQNLCAVFQICDINVLTNDDVEMSRYFENQKYAHFVVLNKLDKVNKSYFNNNKHKIAKFLNISTDRLLCVSAQNNINIITLFALMKKVVIQAKQEKILSKKEEKMSSEEEIK
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: MINE_THISH
Sequence: MNFFNYFRSQKKKSAQVAKERLQVIVARERVHRDGPDYLPRLQEEILNVIRKYVQVDEDAVSIQLERDGDCEVLELNVTLPEHKA
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: MAMF_MAGSA
Sequence: MAEAILLETENTPCGCRSYLMAGLSYLGILCFVPLLMSRDDEYVYFHAKQGLVLWMWSVLAMFALHLPLIGKWLFGFSSMGVLVLSVAGLASVALRRTWRLPLVGYFVALI
What is the function of this protein?
Plays a role in regulating magnetite crystal size; partially redundant function with MmsF.
What are the official names of this protein?
Magnetosome protein MamF.
What is the protein family that this protein belongs to?
Belongs to the magnetosome MamF/MmsF protein family.
What are the subcellular locations of this protein?
Magnetosome membrane; Multi-pass membrane protein. Note=Tagged protein forms straight lines extending along most of the cell associated with its inner curvature, in the correct position to be filaments that are seen associated with magnetosomes. In a mamE disruption MamF mislocalizes as a linear punctate pattern.
Protein: GRAN_MOUSE
Sequence: MAYPGYGGAFGNFSGQIPGMQMQMGQPMPGAGPNMFSGGYPGYLGYSDSYSPADDSMWTYFTAVAGQDGEVDAEELQRCLTQSGISGTYAPFSLETCRIMIAMLDRDYTGKMGFNEFKELWAALNAWKQNFMTIDQDQSGTVEHHELSQAIALMGYRLSPQTLAAIVRRYSKNGRIFFDDYVACCVKLRALTDFFRRRDHLQQGIVNFMYEDFLQGTMTI
What is the function of this protein?
Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin.  May play a role in the formation of focal adhesions.
What are the official names of this protein?
Grancalcin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.
Protein: LEU3_CUPMC
Sequence: MKIAVLPGDGIGPEIVAEAVKVLNALDEKFEMETAPVGGAGYEAEGHPLPDNTLKLAKEADAILFGAVGDWKYDSLDRPLRPEQAILGLRKHLQLFANFRPAICYPELTGASSLKPELVAGLDILIVRELNGDIYFGQPRGVREAPDGLFKGAREGFDTMRYSEPEVRRIAHVAFQAAAKRGKKLCSVDKANVLETFQFWKDIVIDVSKEYPDVELSHMYVDNAAMQLVKAPKSFDVIVTGNMFGDILSDEAAMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGKGVANPLATILSAAMMLRYSLNRAEQADRIENAVKKVLAQGYRTADIVTPGCKQVGTREMGEAVLAAL
What is the function of this protein?
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate.  The product decarboxylates to 4-methyl-2 oxopentanoate.
What are the official names of this protein?
3-isopropylmalate dehydrogenase, 3-IPM-DH, Beta-IPM dehydrogenase, IMDH.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLY1_AMBAR
Sequence: MGIKHCCYILYFTLALVTLLQPVRSAEDVEEFLPSANETRRSLKACEAHNIIDKCWRCKADWANNRQALADCAQGFAKGTYGGKHGDVYTVTSDKDDDVANPKEGTLRFAAAQNRPLWIIFKRNMVIHLNQELVVNSDKTIDGRGVKVNIVNAGLTLMNVKNIIIHNINIHDIKVCPGGMIKSNDGPPILRQQSDGDAINVAGSSQIWIDHCSLSKASDGLLDITLGSSHVTVSNCKFTQHQFVLLLGADDTHYQDKGMLATVAFNMFTDHVDQRMPRCRFGFFQVVNNNYDRWGTYAIGGSSAPTILSQGNRFFAPDDIIKKNVLARTGTGNAESMSWNWRTDRDLLENGAIFLPSGSDPVLTPEQKAGMIPAEPGEAVLRLTSSAGVLSCHQGAPC
What is the function of this protein?
Has pectate lyase activity.
What are the official names of this protein?
Pectate lyase 1, Antigen Amb a I, Antigen E, AgE, Pollen allergen Amb a 1.2, Protein AaBA.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family. Amb a subfamily.
Protein: GLGD_GEOSE
Sequence: MNNKMLGVIDATTYIEALEPLIEQRSIAAVPFAGRYRLIDFVLSSMVNSGIESVAIFPKYQYRSLMDHLGSGKNWDLNRKRDGLFFFPSPDLLFSGERRVGAFAHFEQHIDYFLRSRQKYAVIANGYTVCNIDFDAVLNRHIENGCDVTEIRHRGRSLEMYLLETSLLLDLIADYKNHGYYSIVDVIRDYHRSLSICEYEYSGYAAVIDSVEQYFRSSMELLDRDVWEQLFLPSHPIYTKVKDEPPTKYGREGNVKRSMIANGCVIEGTVENSVLFRSVKIGKGAVVRNSIIMQKCQIGDGCVLDGVIIDKDAKVEPGVVLKGTKEQPFIVRKGTVQGEVISR
What is the function of this protein?
Required for the synthesis of glycogen.
What are the official names of this protein?
Glycogen biosynthesis protein GlgD.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: SH3R2_RAT
Sequence: MDDLTLLDLLECPVCFEKLDVTAKVLPCQHTFCKPCLQRIFKAHKELRCPECRTLVFCSIEALPANLLLVRLLDGVRSGHNSWRGGSFRRPRILTLQDNRKAKSSPRSLQASPFRLGPTVRIHMDGVPRAKALCNYRGKNPGDLKFNKGDVILLQRQLDENWYQGEINGVSGFFPASSVEVIKQLPQPPPLCRALYNFDLRDKDKSENQDCLTFLKDDVITVISRVDENWAEGKLGDKVGIFPILFVEPNLSARHLLEKSKGHQLSRTKHLSLMSSPSRGKATNTSTLRKSPGSRRKGSGQFAMTTALNTLNRMVHSPEGHQMVEISTPVLISSTSPSMLTQHGDRADFPASSAGQVSTSHPAPASPGHSTAMVSVPSSQQHLSTNMFVALHTYSAQGPEELDLKKGEGIRVLGKNQDGWLRGVSLVTGRTGIFPSDYVIPVFSSTARKTSSFPDSRHPTVCTTWALSTSSVSSQGSFSEGDPRQSGPFRSVFVPTAVNPPRSTSGPGTSGQGSLRKVRSSMRKNGSLQRPVQSGIPTFMVGSLRCSPAMVIRPQKFQFYQPQGMTPSPTPIMVEIGSKSISTGEPALTCINRGGKTRTHSAGNSIIMEGKETPIKSEPPPKPPASAPPSILVKPENSKNGIEKQVKTVRFQNYSPPPTKHSASGPTSGKHEQPATLKGSQPEAVSSEGEMTILFAHRSGCHSGQQTDLRRKSAFSKTTPPVSTASVSQTLFPSK
What is the function of this protein?
Has E3 ubiquitin-protein ligase activity.  Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169).  Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation.  Inhibits PPP1CA phosphatase activity (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase SH3RF2, POSH-eliminating RING protein, Protein phosphatase 1 regulatory subunit 39, RING finger protein 158, RING-type E3 ubiquitin transferase SH3RF2, SH3 domain-containing RING finger protein 2.
What is the protein family that this protein belongs to?
Belongs to the SH3RF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RNPA_BRUC2
Sequence: MKSKKQILRLRKRAEFLTVRNGEKRRGPLFLMEVRERTEEESNAAKTGDNPRVGFTVTKKNGNAVIRNRIRRRLKEAIRCHAGRDMAPSTDYVIVAREQALNAPFSQLTEELSRRITAKGERRSGGKRRTERPEPGPVNGK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RR18_SOLBU
Sequence: MDKSKRPFLKFKRSFRRRLPPIQSGDRIDYRNMSLISRFISEQGKILSRRVNRLTLKQQRLITLAIKQARILSLLPFLNNEKQFERTESTARTTGFKARNK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NRDR_BDEBA
Sequence: MKCPFCGHADDRVLDTRVQKDGSIRRRRECLECKARFSTVETIMLAFPFIIKKDGRREPFSKEKILKGLQASCQKRPVSLAQIDAVVEKISAWVINRGESEISSRLIGKKVMAELKQLDDVAYIRFASVYRTFKDVQEFVETLEDAELLDFVDASNPQLSLTAMTFVESEKSTNHETDSKTPSPRTRPPGPLSN
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: SECA2_STAA8
Sequence: MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTIEFKERLASGVDTLDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTGEGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVDYEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIILDAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSYFNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQAGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKIVVQVPTDKAIQRIDEPDKVFRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFSKVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGGLAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYSLDAQRLSQSNLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNRVLEIDDAENQDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKDKQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKASVNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP
What is the function of this protein?
Part of the accessory SecA2/SecY2 system specifically required to export SraP, a serine-rich repeat cell wall protein encoded upstream in the same operon.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: SYGB_DESHD
Sequence: MAKDFLLEIGTEEIPAKFAPGVLNQLREQAQKYCQELRLDYQDLKVYTTPRRFAVLIQGLAEKQTDFTAEVKGPAVKAAYDAEGNPTKAAQGFARGQGVEPKDLFVQELNGVSYVYARKFELGQPTLQLLPKLCTDLITGLHFPKPMRWADLEFRFARPIRWIVALFGSEVIPFEFVGLASGKASRGHRTLGGPVTLDSPADYEKQMLQAFVMVDPEQRRQSVWEQIHALAAKVGGDVEKDDDLLDEVTHIIEYPTALLGEVAPNYMHLPEPVITTPMKEHQRYFPVRDKEGKLLPYFITVRNGDDYALAKVKAGNEKVLKARLEDAAFYYREDQKTPLAELVEKLDKVTYHEKLGSVRQRVERIRTLARGIAARLGMESEKQDLVERTALLAKADLVTLMVYDFPELQGIMGADYARMVGEKPEVCTGILEHYQPRFAGDELPQSYTGQIVSVADKLDAIVGAFGIGIQPTGSQDPYALRRQAQGVVGIILEAGWDISLEQLIAASYVNFAEQGISLLPLADLQSALQDFFQQRLRFVLQEQGARYDTLDAVLAQGSNQITRAARKAQVLAAKRETTEFVPYSQAYIRCLNLSKKAQTQPLDPKNLIDPTEIALAAALVQRQEAFAALIEKGDYAEAYALASELIPMIEALFNAVMIMVEDEILKQARLALLGECVAILGCLGDLSLLA
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASB5_RABIT
Sequence: MSVLEESRPFAQQLFNVYFTILSLFCFKLFVKISLAILSHFYIVKGNRKEAARIAAEFYGVTQGQGSWADRSPLHEAASQGRLLALRTLLSQGYNVNAVTIDHITPLHEACLGDHVACARTLLEAGANVNAITIDGVTPLFNACSQGSTSCTELLLEYGAKAQLESCLPSPTHEAASKGHHEFLDLLISWGIDVDQDIPHLGTPLYVACMSQQFHCIWKLLYAGADVQKGKYWDTPLHAAAQQSSTEIVNLLIEFGADINAKNTELLRPVDVATTSSMVERILLQHEATPSSLCQLCRLCIRNYIGRPRLHLIPQLQLPTLLQNFLQYR
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).  May play a role in the initiation of arteriogenesis.
What are the official names of this protein?
Ankyrin repeat and SOCS box protein 5, ASB-5.
What is the protein family that this protein belongs to?
Belongs to the ankyrin SOCS box (ASB) family.
Protein: CYOE_AZOVD
Sequence: MATLLATRGNRATWRDYLELTKPKVVVLMLITSLVGMFLASRAGVPWTVLLFGNLGIGLCAGAAAAVNHVVDRRIDALMARTRRRPLAEGRVAPLAALGFALALAVAGMALLLTFTNPLAAWLTLASLLGYAVLYTGFLKRATPQNIVIGGLAGAAPPLLGWVAVSGQLSAEPLLLVLIVFTWTPPHFWALAIHRKAEYAKAEIPMLPVTHGEAYTKLHILLYTLALLAVTLLPYAIHMSGPLYLLCALLLGGRFLHWAWALYKDSKPHAAIGTFKYSIRYLFLLFIALLVDHYLPLTL
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UFSP2_DROPS
Sequence: MLPKLKISAFLLKRLERVKQQSSGCLYGVFYGDGTLLLLSFNLSNVGQLNYEQIQHRFPAELDLCGLVKFGDCTDAEAHLNEVIKSVDITDNPILLKCELGTLVGMRASFFVHGKLEEVPYDVMDSEQLYNDFCFTRLQCGFYLQTAATPECVAKEMHVLRKRVADGNLVFKVPHTNIYIHSCGPMDNKLRGESRINDLVQAIPIPSGKENVVADKKKSKTAAQTQLAKHFGATGCEYDLINIDVMRIRTRDLLARDSPPHPALSIAVTTEEQTRAQVPLEIEAMAMLCKNTKLQRLYDVLIESICRALRLFEQSLNEHLAESEGGSLAVPRSHHFYPQGFGHFLSCAYLEGLGDDEPIMQERRKRLHRQFSLPVTRPYFRRANQCHFQGEVDDAPWTPLLNTHVGVRPSAVTDGKEYLVNGNYHYYHYLQQQVQDKGWGCAYRSLQTICSWFVLQGYTNAPIPTHLEVQKYLHKINDKPSSFVGSSQWIGSTEISMCLQGFLKVDSKILHVSSGAELPTIASELAMHFQTQGTPVMIGGGVLAHTIIGVDYCVQSGEVKFLILDPHYTGADELATIQIKGWCGWKSMDFWSKGSYYNLCMPQRPILY
What is the function of this protein?
Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins.  Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins.
What are the official names of this protein?
Probable Ufm1-specific protease 2, UfSP2.
What is the protein family that this protein belongs to?
Belongs to the peptidase C78 family.
Protein: ERPA_SHEPC
Sequence: MTEQADAAMPIQFTDAAAAKVKGLLEEEQNPALKLRVYVTGGGCSGFQYGFTFDEKVNEGDFTVEKQGVQLVVDPMSLQYLVGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters for at least IspG.
What are the official names of this protein?
Iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: ADK_CRIGR
Sequence: MAAAEEPKPKKLKVEAPQALSENVLFGMGNPLLDISAVVDKDFLDKYSLKPNDQILAEEKHKELFDELVRKFKVEYHAGGSTQNSIKVAQWMIQKPHKAATFFGCIGIDKFGEILKSKAAEAHVDAHYYEQNEQPTGTCAACITGDNRSLVANLAAANCYKKEKHLDLENNWVLVEKARVYYIAGFFLTVSPESVLKVARYAAENNRIFTLNLSAPFISQFFKESLMEVMPYVDILFGNETEAATFAREQGFETKDIKEIAKKAQALAKVNSKRPRTVVFTQGRDDTVVATENEVMAFAVLDQNQKEIIDTNGAGDAFVGGFLSQLVYNKPLTECIRAGHYAASVIIRRTGCTFPEKPDFH
What is the function of this protein?
Catalyzes the phosphorylation of the purine nucleoside adenosine at the 5' position in an ATP-dependent manner.  Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.
What are the official names of this protein?
Adenosine kinase, AK, Adenosine 5'-phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXH_HAEDU
Sequence: MDLHNIRADYTKQQLSKKECDANPMKQFERWLNEAIMAKVNEPTAMNMATVIDGKPTSRIVLLKEVDQQGFIFFTNYQSCKGWAIALNPYVALTFFWPELERSVRVEGIATKLSEQASDDYFASRPYASRIGAWASDQSQVLSSKRTLVAKVALLSAKYPLFVPRPAHWGGYLVQPTKIEFWQGRPSWLHDRICYWLVENEWLKERLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: AROK_SYNE7
Sequence: MSLVTALNGLDLFLVGLMGSGKTTIGKLLAESLGYTYVDTDSLIENVTGRSIPEIFASDGEAGFRQIETQVLEEVASYRRLVVATGGGIVIRPENWSYLQQGLVIWLDVPIPELLRRLEGDQNRPLLQTEAPATTLQALWEQRRDRYAQADLRIAIEASEDPEVTMQRILEVIPSVLKNSADSSPAEIET
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YYAT_BACSU
Sequence: MNIKRITTEADLHEALKIRRGVFIEEQHVSEADEFDEFDTLQEQCQHILVYHENQPVGTGRARIVGHTAKLERICILKPYRKYGLGKIIVSGLEEIMKEKGLTSYKLHGQTQAAGFYQKLGYQISSQEFMEDGIPHVLMTKEISRNIT
What are the official names of this protein?
Uncharacterized protein YyaT.