PharMolix/UniProtQA huggingface dataset:
Protein: PFLA_STAEQ
Sequence: MLKGHLHSVESMGTVDGPGLRYILFTQGCLLRCLYCHNPDTWKINEPSREVTVDEMVNEILPYKPYFEASGGGVTVSGGEPLLQMPFLEQLFKELKANGVHTCIDTSAGCVNDTPAFNRHFDELQKHTDLILLDIKHIDNDKHIKLTGKPNTHILKFARKLSDMKQPVWIRHVLVPGISDDKEDLIKLGEFINSLDNVEKFEILPYHQLGVHKWKNLGIPYQLENVEPPDDEAVKEAYRYVNFNGKIPVTL
What is the function of this protein?
Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
What are the official names of this protein?
Pyruvate formate-lyase-activating enzyme, PFL-activating enzyme.
What is the protein family that this protein belongs to?
Belongs to the organic radical-activating enzymes family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP6_ROTRH
Sequence: MNHLQRRQLFLENLLVGVNSTFHQMQKHSISTCCRSLQRILDHLILLQTTHSPVFRLDRMQLRQMQTLACLWIHRHNHDLQVTLDAIKWISP
What are the official names of this protein?
Non-structural protein 6, NSP6.
What is the protein family that this protein belongs to?
Belongs to the rotavirus A NSP6 family.
What are the subcellular locations of this protein?
Host cytoplasm. Host mitochondrion. Note=Found in spherical cytoplasmic structures, called viral factories, that appear early after infection and are the site of viral replication and packaging.
Protein: RS9_BUCBP
Sequence: MENMYQYGTGRRKSSSARVFLKTGTGNITINNRKLNNYFSRRTARLIILQPIEFVNMSKKCDLYITVKGGGISGQVGAIRHGISRALIKYDSSFRNELRKLGFITRDSRQVERKKVGFRKARKRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: NUOH2_RHOPS
Sequence: MAEFFATNLWPLIIVIGQSVLLLVLLLISIAYILLADRKIWAAVQLRRGPNVVGPWGLLQSFADLLKFVVKEPTVPSGANKGVFLLAPLVTCVLALAAWAVIPVNAGWVIADINVGVLYILAVSSLSVYGIIMAGWSSNSKYPFLAALRSAAQMVSYEVSIGFVVICVLLCVGSLNLTAIVEAQNSQWGMLGWYWLPLFPMFVVFYVSALAETNRPPFDLVEAESELVAGFMVEYSSTPYLLFMLGEYVAIVTMCAMGTILFLGGWLPPVPYAPFTWVPGIVWFALKVLFMFFLFAMAKAIVPRYRYDQLMRLGWKVFLPLSLAMVVIVAAVLQFAGLAPK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H 2, NADH dehydrogenase I subunit H 2, NDH-1 subunit H 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SGO1_CAEBR
Sequence: MNAKAAQSLFGAIASSKKAPTREEPAVNFKSTNESLIKKNLQLKQQLSQCTKALEKLRNENIALREQNQELIDATLDEKMERIVEQRVKSRLAHAAVLHKKLVQNIQQTGLELGGIFKDMEPEPSGMVTRRAPKMECNLEKLDESPVRNFPRSDYEEENKSPMDIQNGPSSSSSMTQNLENGTPRMAQRASKGRRSELFHSLHENVPEEAAPAVGYKRAPLLIAPSETPGGPPKKAPPRKAPTPRFKKPSTPAPAPISDDAEMPSTVRRQRSAKMNIKSMKEPSVNSKLRRPGKHDEPMPFIDTFF
What is the function of this protein?
Plays a central role in chromosome cohesion during cell division by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms.
What are the official names of this protein?
Shugoshin.
What is the protein family that this protein belongs to?
Belongs to the shugoshin family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere.
Protein: PYRH_ECOL6
Sequence: MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADVVLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLITE
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR7_PYRFU
Sequence: MEIYEGKAKKMIPLDEDKFIMEFKDDATAFDGVKKAKFVGKGWLNAQISAKLFKLLEDHGIKTHFIGVAGGNRLIVERLEMYPIEVVVRNVVAGSLKKRLPLPEGYELPEPIVELYYKSDELHDPMINYYHARILGISEEEIKEMERIALKVNEILKKFFREKGIILVDFKLEFGKNKKGEIVLADEISPDTCRFWDVETKKSLDKDVFRFDKGDLIEAYKELYKRLIGEEPQI
What are the official names of this protein?
Phosphoribosylaminoimidazole-succinocarboxamide synthase, SAICAR synthetase.
What is the protein family that this protein belongs to?
Belongs to the SAICAR synthetase family.
Protein: DCD_NEIMA
Sequence: MSIKSDKWIRRMSEEFGMIDPFEPNQIKEADGKRIISYGTSSYGYDIRCANEFKIFTNINSTIVDPKNFDPKNFVTVEDDCCIIPPNSFALARTVEYFRIPRNVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYAGEGVAQVLFFESDEICETSYKDRNGKYMGQTGVTLPKA
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: CASP1_MAIZE
Sequence: MKGSSEHGETSKQAPLGSSRGVSKGVSVLDLILRFIAIIGTLASAIAMGTTNETLPFFTQFIRFKAQYSDLPTLTFFVVANSIVCAYLTLSLPLSIVHIIRSRAKYSRLLLVVLDAAMLALVTPGASAAAAIVYLAHKGNVRANWLAICQQFDSFCERISGCLIGSFGAMVMLVLLLLLSAIALARR
What is the function of this protein?
Regulates membrane-cell wall junctions and localized cell wall deposition.  Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity).
What are the official names of this protein?
Casparian strip membrane protein 1, ZmCASP1.
What is the protein family that this protein belongs to?
Belongs to the Casparian strip membrane proteins (CASP) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Very restricted localization following a belt shape within the plasma membrane which coincides with the position of the Casparian strip membrane domain in the root endodermis.
Protein: EFGM_ANOGA
Sequence: MTISNLIRSRCSLAAAKSFLENVKSFSSHATFAEHKQLEKIRNIGISAHIDSGKTTLTERILFYTGRIKEMHEVKGKDNVGATMDSMELERQRGITIQSAATYTIWKDHNINIIDTPGHVDFTVEVERALRVLDGAVLVLCSVGGVQSQTLTVNRQMKRYNVPCLAFINKLDRSGANPYRVLGQMRSKLNHNAAFVQLPIGVESNCKGVIDLVKQRALYFEEPYGLKIREDEIPADMRTESAERRQELIEHLSNVDEKIGELFLEEREATVEDIMGAIRRSTLKRAFTPVLVGTALKNKGVQPLLDAVLDYLPHPGEVENVALVEKKDEEPQKVPLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFNTRSGKKIRLARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFVTNPKLELSMESIFVPDPVVSMAIKPTNSKDRDNFAKAIARFTKEDPTFHFEYDADVKETLVSGMGELHLEIYAQRMEREYNCPVTLGKPKVAFRETLIGPCEFDYLHKKQSGGQGQYARVSGILEPLPPHQNTTIEFVDETMGTNVPKQFIPGIEKGFRQMAEKGLLSGHKLSGIKFRLQDGAHHIVDSSELAFMLAAQGAIKSVFENGSWQILEPIMMVEVTAPEEFQGTVIGQLNKRHGIITGTEGAEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFSMEYSRYSPCMPEVQEKLCHEYQVSQGLVVDKKQKKKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: SPEE_AERPE
Sequence: MAGGSEKSVFLKWSWFLEWLTPDRATLKHIEDVIFQGRSRFQEIAVVRVSGEGKVLVLDGKTQSSESDEFMYHEALVHPAMILHGSPRKVLILGGGEGATLREVLKHRSVEKAVMVDIDETVVNVAREHLREWHRGAFDDPRAEVVIDDAWNYVASKAETGFDVVIADLVDPLEAGPATRLYSEEYYRMVKDVMNPGGVFVTQAVSISHLTEYHAIIRNTVARVFKHVESYGVYVPSFDSMWGFVVASDDKDPRILGDRGFFETRLSHQLQGAELRFLDYASMLHMLNIPKMYREAIAREKRYATLDNQVFLPA
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_HELPH
Sequence: MANHKSAEKRIRQTIKRTERNRFYKTKVKNIIKAVREAVAINDVAKAQERLKIANKELHKFVSKGILKKNTASRKVSRLNASVKKIALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RL33_ALKEH
Sequence: MRDKIKLVSTAGTGHYYTTDKNKRNTPHKLEFRKYDPVVRKHVLYREAKIK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: G1PDH_PYRAR
Sequence: MKQLESFEIPRTVIFGPGAISKTPQVVAKHKAERILIISGKSVTANYANEVAHLLSGYSVDVVRYDEVDTSYSKYDLVLGVGGGRPIDVAKVYSYLHRAPLIVIPTSASHDGIASPYVSYALSQKMASHGKIVASPIAIIADTTVILNAPSRLLKAGIGDLLGKIVAVRDWQLAHRLKGEEYSEYAAHLALTSYRIVVSNAFRIKNFTKEEDVRVLVKALIGCGVAMGIAGSSRPCSGSEHLFAHAVELLLGEKNNEAIHGELVALGTVVMAYLHGMNWRRIKRVAKEVGLPTTLKQIGIDADVAIEALTTAHTLRPDRYTILGSGLGKEAARRALETTELI
What is the function of this protein?
Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P).  The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea.
What are the official names of this protein?
Glycerol-1-phosphate dehydrogenase [NAD(P)+], G1P dehydrogenase, G1PDH, Enantiomeric glycerophosphate synthase, sn-glycerol-1-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the glycerol-1-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_BACLD
Sequence: MRKIGIFGGTFDPPHNGHLLMANEVLYKLDLDEIWFMPNQIPPHKQKNSFSLSMHRVEMLKLAISGKEQFKLETIELEREGPSYTFDTVRLLKDRYPDHEFYFIIGADMVEYLPKWSNIDKLVNMIQFVGVKRPGFQIETPYPLVFVDVPIFEVSSSLLRDRIKNRQPTDYLIPDEVKVYVKENRLYET
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: SYFB_METJA
Sequence: MPTINVKKADLERLVNMPLEDEFIEEKFPMMGVEVEGIFEEDGEKIIQFSINPNRPDYLSAEGLARGFRGIIGIETGLKKYDIESSDVKLYVENVETRPYIAMALVKGVIVDDYVLESIINLQEKLHWVMGRDRKKVAIGIHDADKVKPPFYYKEVSGDGIKFVPLNSDEEMTPREILEKHEKGIKYAHLIKDDKFPIILDSEGDVLSMPPIINGELTRVTTETRNLLIDVTGTDKYAVEKTLNIIVTALAERKYGKIHAVEVIKDNQSTIYPNLKEDVLETTSEYINKVLGANLTPGTIINYLRRCRLDAQFVDNKIKVFIPAYRVDIFGEIDIAEEVAIAYGYNKFSGEYPIIGTIGELNQLEKKCDFIREIMVGFGFYEVINLMLSNDEVLFKKMRIEDNNYIEVLKPASIEHRIVRKSILPLLMETLRINKHKELPQKIFEIGDCVVIDENAETKSRVVKKIAGVIVDNETNFNEIKSYVEGLLRELKIEYELDNFEHPSFIKGRCAKILKDGKIIGYFGEIHPEVITNFELEFPVVGFELEIE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAGI3_RAT
Sequence: MSKTLKKKKHWLSKVQECAVSWAGPPGDLGAEIRGGAERGEFPYLGRLRDEPGGGGGTCCVVSGKAPSPGDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSIDHKLQQVIRDNLYLITIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGTYDGNFYGTPKPPAEPSPFQPDPVDQVLFDNEFDTESQRKRTTSVSKMERMDSSLPEEEEDEDKEAVNGSGSMETREMHSESSDCWMKTVPSYNQTNRSMDFRNYMMRDENLEPLPKNWEMAYTDTGTIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIEDPQYGTYYVDHLNQKTQFENPVEEAKRKKQIGQAETHSAKTDVERAHFTRDPSQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKMAPGDVIVDINGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYALPDDSEDPVVDIVAATPVINGQSLAKGEACMSTQDFKLGAMVLDQNGKSGKLLSSDRLNGPSDSNEQRASLASSGSSQPELVTIPLVKGPKGFGFAIADSPTGQKVKMILDSQWCQGLQKGDIIKEIYHQNVQNLTHLQVVEVLKQFPVGADVPLLILRGGPCSPTKTAKMKTDTKETSGSLETINEPTPQPMPFPPSIIRSGSPKLDPSEVYLKSKTLYEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDESPQAFSQSGSPRLNRTELPTRSAPQESYDVILQRKENEGFGFVILTSKSKPPPGVIPHKIGRVIDGSPADRCGRLKVGDHISAVNGQSIVDLSHDNIVQLIKDAGVTVTLTVVAEEEHHGPPSGTNSARQSPALQHRPMGQAQATHIPGDRTALEGEVGKDVCSSYRHSWSDHKHLAQPDTAVISVVGSRHSQSLGCYPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHGDWDIYSPSSSNVIYDEQPPPLPSSHSAATFEESHVPVTEDSLIRVQTCEKAEELKDTVQEKKSTLNGSQPEMKYQSIQKNVSKKDPSRSHGHGDKNLLKGENGVTRRGRSASPKKSVNRHSEEHLEKIPRPLRSDPKGKSRDRSLSPRKGENKGQVTIKAGSGQDPCRKDRGRSSSPRKQQKIGGNSLSNTEGKLSEAGSRRAAGLSSDSPEQLPEGKEKSGVSRKDLKLSQLGKNRTRSPEKRSSKVDEASLPSKKTSDTASRVVSEKEKGRKPGTGERSRDKTGESVQTSAKPLTQEAGEKMALSKASEVTDRGKERAGGAPESSSPVKKAPITPGPWRVPRANKVTGTAGMADKQL
What is the function of this protein?
Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes.  Cooperates with PTEN to modulate the kinase activity of AKT1.  Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane.  In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface.  Regulates the ability of LPAR2 to activate ERK and RhoA pathways.  Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2.
What are the official names of this protein?
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3, Membrane-associated guanylate kinase inverted 3, MAGI-3, Scaffolding-like protein.
What is the protein family that this protein belongs to?
Belongs to the MAGUK family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Nucleus. Note=Concentrates in specific sites at the plasma membrane and in the nucleus. In epithelial cells, it localizes at tight junctions.
Protein: MSB1_YEAST
Sequence: MNDMAKPLPTPPTAEIRKSRSNSPKKAQKTNLSPNKNQNNEKNVPRSNGRTKNEHNSMDDEEFEFFHQFSREKVKGVIHVITAELKEKGPDVEFLMIPFRPEQTNDKLLTLLNQLFPLGNGQPVNEKKQLRIVSKADVWTLFQCLKYIWCRLPNSEIIGWKSYLEFKFREEDKKFPRKSFLEIMPQCLASPNHASIVYDFFDLIISISSNSRVNKMSARKISKMCAIWAFSKQIPNSDIQDYDFESAAMKSFAPNNSIQDGLDQWIPASDAMFHLLLAFLRSFVPQDLESAKLPRTLKSLLFNNQYPPRKSTAYTSETILTIPLVTLKTDVFSRKPWQLLERCNDLLDFSDHDAFEAREDYALLKSLFRKKNTVEGISRKMSQESRRLMKAMSTKHSTFQPGWAPRECIENISHLKECIEVKRLDIDDYFIWTWLSSLSFEQTSEKKKIFGRSIILEFEFDGFKKWVVFQECDITLDYNKKGQLKKKTSAQSPTTEKELPPDDFELEDPPLSKSPTLSQTYKKFQAEVPQQSTVRRDSAPDNQGIYHTVISKNALTKNKHNVNLHSFEHKISKWNPLNNLRKKSGSNSSSSSFEEKSKDAPIREEYHTNKNHKSKKEERVLSQFSTLNPDEYQLPVIETGSSNFKIEIPELMYEHDDDDSDKLKNSQKRATDSAIEELNGMVEEMMINEPDDVKISITEAETFESLTKFDQYKPSNITDDDLQSSHSSAVHSLKLSTNTNDSCADSSKYTADRKLAEPRKISEESKVNDDSSSYYSPNINNLPASRMPSQPTYSNSDSKKAFTNESRLNVLQGAVSPSQQVTPKPYKNAPGDCVSPVQQKYYQNDRRNEMSPASAPVPPSAYSPARSPQFSTNSAGFKQNTINVPVGYNDPAHVLANQPHMTYRDQHNYPSHQQKQRPFQNNIVPPELKSRNQRADASPIPQHMVPVKQGVPNLPSNVPLYQQMERMNPNHQHPVNTYKVTQPPYHNNTTNAYGNSRAGNAHMLDGKWSNNPPQMVPKGVRPNQYPQQHVNRYSPQAQPVVPAEYYNGPPPMRAPPMMSHMVPAQEPIRYTAGANRRSFPQGMQQNAYSVPAQPMGAVNSEFYLPEAPQGNKLHGNINKRQERKKLYDNIRSGNFGI
What is the function of this protein?
May play a role in polarity establishment and bud formation.  The MSB1 gene may be functionally redundant.
What are the official names of this protein?
Morphogenesis-related protein MSB1, Multicopy suppressor of bud emergence 1.
Protein: HOSA_SACS2
Sequence: MIKVGILDSTLREGEQTPGVIFTVDQRVEIAKALSDLGVSMIEAGHPAVSPDIYEGIKRIVKLKKEGIITSEIVGHSRAVKRDIEIAAELEVDRIAIFYGVSDIHLKAKHKATREEALRVIAETISYARSHGVKVRFTAEDGSRTDFDFLVTVSRTARDAGADRVSIADTVGILYPSKTKELFSALIREVPNLEYDIHAHNDLGLAVANALAAVEGGATIVHATVNGLGERVGIVPLQQIVAAIKYHFGIEVVKLDKLQYVSSLIEKYSGIPMPPNYPITGDYAFLHKAGVHVAGVLSDPRTYEFMPPETFGRTRDYTIDKYTGKHALRDKYEKLGVKISEAEMDQILAKIKSNTTIRFYRDVDLLELAEEVTGRVLKPRPPEQIEALISVKCDSNVYTTSVTRRLSVINGVKEVMEISGDYDILVKVQAKDSNELNQIIESIRATKGVRSTLTSLVLKKM
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
Protein: CLP1_PICGU
Sequence: MSIPGFGGDENPVEDLSETNATTFHLEGKSEWRFEVPFKTILSLKVTEGVGEIFGTELPLNVPVQLTGVKYALYAPLPEGCTVEYSTRINRDQAPGSSDSTDISEYISEDTPMNQYINLHMALESYRQETADYNYLNPSSPRSGPRVLILGNRSAGKTALARILSSYAYKMDHHPVLVNLNPRDGVFSLPGSLTATPISDTFDLESANGYGGTTTSGSAVHNPKQPVVKNFGFLSPTDNLELYKYQVSKLGVVVMSRLEEDADVRNSGVIIDTPALNIKDINVIENIVSDFEVNVVVVVDNERLLIDLRKKFKHKISNSQLAMVKIPKSGGVVELDDSFIRQCQEETIKEYFNGDRKTPLSPFKTEVDVKDFRYFKGVLSSDFNPSLSFLPSGDSYTTDDMDEDRKKDENSMDKFYTALEDPDASKLENLIIAITQLPQNNKQPKDLLNTCVLGYIHVSRVDEARGKMKVLSPMVAAIPRNILLVTTIGYTE
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor CLP1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: METN_HAEI8
Sequence: MIKLNNITKIFELPNKKLTALDNVSLNIEKGQICGVIGASGAGKSTLIRCVNLLEKPTSGSVIVDGVELTKLSDRELVLARRQIGMIFQHFNLLSSRTVFENVALPLELESESKAKIQEKITALLDLVGLSEKRDAYPSNLSGGQKQRVAIARALASDPKVLLCDEATSALDPATTQSILQLLKEINRTLGITILLITHEMEVVKQICDQVAVIDQGRLVEQGTVGEIFANPKTELAQEFIRSTFHISLPDEYLENLTDTPKHSKAYPIIKFEFTGRSVDAPLLSQASKKFGVELSILTSQIDYAGGVKFGYTIAEVEGDEDAITQTKVYLMENNVRVEVLGYVQ
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y9388_RHILO
Sequence: MKIVYVVGTCDTKGSELRYLRDLIRDAGCDVVLVDVSVSEFHSEASDVDVQPAEVARCHPNPLKAEELKDRGKAVAAMSQALVEYIRSRPDVDGIIGAGGSGGTALIAPAMRALPIGVPKVLVSTVASGNVAPYVGPTDISMMYSVTDVSGLNRISRVVLANAAHSIAGMVLKQVGAAADERPAIGLTMFGVTTPCVQAVTRALEANFDCLVFHATGTGGQSFEKLADSGLLVGGIDVSTTEVCDYLVGGVFPCTPDRFGAFARTKLPYVGSCGALDMVNFGAMETVPSQFRSRRLHVHNPQVTLMRTNPEECSRIGEWIGERLNLCEGPVRFLIPELGVSAIDAPGQPFHDPEADAVLFAALERTLRCTDKRQLARVPLHINDPQFADLLVTNLKEAFREH
What are the official names of this protein?
UPF0261 protein mll9388.
What is the protein family that this protein belongs to?
Belongs to the UPF0261 family.
Protein: PYRF_MALP2
Sequence: MSNREVIIALDFDSLDKTCKFLNLFENQNLFVKIGMELFYQNGLQVLHEIKNRGHKIFLDLKLHDIPNTVYHAVKGLMKFDVDIITVHCAGGLTMLNQAKQAVFDQNKNTKIIGITQLTSTSETEMQTQQKISTSLQDSVLNYAKLAKEANIDGVVSSVWETKKIKEQNGNNFLVINPGIRLEKDDSGDQKRVASPLDAKNQLADFIVVGRPITKDNNPLEKYLEIKRMFV
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: TSAD_SACD2
Sequence: MRVLGIETSCDETGVAIYDSEAGLLGHTLYSQVAVHAEYGGVVPELASRDHVRKLLPLVDGLLDNTDSRNKIDAIAYTSGPGLIGALLVGACFGRGLAMAWGCPAIGVHHMEGHLLAPMLEDAPPAFPFVALLVSGGHTQLVEVQGIGKYVLLGESLDDAAGEAFDKAAKMMDLDYPGGPNIAKLATKGDVSRFKFPRPMTDRPGLDFSFSGLKTFTLNTVAKYADETGLPDDQTCADIACAFQEAVVDTLVIKCRRALQQTKLNTLVIAGGVSANVRLRERLEAALAKINSQVYYARPEFCTDNGAMIAYAGCQRLLAGQVEPLAINVSPRWALDTLPAI
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOAA_ESCF3
Sequence: MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFQAITGQDKFNQVMAGIDAAFEAGFEKVKVNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG
What is the function of this protein?
Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
What are the official names of this protein?
GTP 3',8-cyclase, Molybdenum cofactor biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. MoaA family.
Protein: XPR1_DANRE
Sequence: MKFTEHLSAHITPEWRKQYIQYEAFKEMLYSAQDQAPSIEVTDEDTVKRYYAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQRESSRAAGLRHRRTVFHLSQQERCKHRNIKDLQLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKIFETSRGADWRVAHVEVAPFYTCKKITQLISETETLVTTELEGGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLYCGVFVALTVTVIIAGVVKLVEHFGDNTDVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLFEIAGFLGVLWCVSILSCLFAENTLIPIHMNPLALYGFFFLFLINPLKTCYYKSRFWLLKLLFRVVTAPFHRVGFADFWLADQLNSLVVVLMDLEYMICFYSLELNWTMSEGELWIKEGERICYSYSYGVRAVIKCLPAWFRFVQCLRRYRDTKRAFPHLVNAGKYSTTFFVVIFEALFKTHSGDERFVFLYIMIACRIVNSCYTLLWDLKMDWGLFDRNAGENTLLREEIVYPQKAYYYCAIVEDVILRFAWTIPLSLEVVYDRPVISNILGTVLPPLEVFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQEDGVRNRLGKKNWKRSYSMSLRRPRLSSQSKVRDTKVLIEDTDDDT
What is the function of this protein?
Plays a role in phosphate homeostasis.  Mediates phosphate export from the cell (PubMed:23791524).  Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules (By similarity).
What are the official names of this protein?
Xenotropic and polytropic retrovirus receptor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the SYG1 (TC 2.A.94) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.