PharMolix/UniProtQA huggingface dataset:
Protein: FOXA2_MOUSE
Sequence: MLGAVKMEGHEPSDWSSYYAEPEGYSSVSNMNAGLGMNGMNTYMSMSAAAMGGGSGNMSAGSMNMSSYVGAGMSPSLAGMSPGAGAMAGMSGSAGAAGVAGMGPHLSPSLSPLGGQAAGAMGGLAPYANMNSMSPMYGQAGLSRARDPKTYRRSYTHAKPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFLKVPRSPDKPGKGSFWTLHPDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAASSGGKKTAPGSQASQAQLGEAAGSASETPAGTESPHSSASPCQEHKRGGLSELKGAPASALSPPEPAPSPGQQQQAAAHLLGPPHHPGLPPEAHLKPEHHYAFNHPFSINNLMSSEQQHHHSHHHHQPHKMDLKAYEQVMHYPGGYGSPMPGSLAMGPVTNKAGLDASPLAADTSYYQGVYSRPIMNSS
What is the function of this protein?
Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues.  Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites.  Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity).  In embryonic development is required for notochord formation.  Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; Foxa1 and Foxa2 seem to have at least in part redundant roles.  FOXA1 and FOXA2 are essential for hepatic specification.  FOXA1 and FOXA2 are required for morphogenesis and cell differentiation during formation of the lung.  FOXA1 and FOXA2 are involved in bile duct formation; they positively regulate the binding glucocorticoid receptor/NR3C1 to the IL6 promoter.  FOXA1 and FOXA2 regulate multiple phases of midbrain dopaminergic neuron development; they regulate expression of NEUROG2 at the beginning of mDA neurogenesis and of NR4A2 and EN1 in immature mDA neurons.  Modulates the transcriptional activity of nuclear hormone receptors; inhibits AR-mediated transcription from the LCN5 promoter.  Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.  Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc.  Interacts with the cis-acting regulatory regions of these genes.  Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis.  In pancreatic beta cells activates transcription of potassium channel subunits KCNJ11 and ABCC8.  Involved in regulation of fat metabolism; activates transcriptional programs of lipid metabolism and ketogenesis at low insulin state.  Involved in transcriptional regulation of MUC2 in the intestine.
What are the official names of this protein?
Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, Forkhead box protein A2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm in a CRM1-dependent manner; in response to insulin signaling via AKT1 is exported from the nucleus.
Protein: RSMH_MYCLE
Sequence: MPSDRDHDAGIFAFFGAVPRSDRCRQTRGGGEVVDGSSVFGHVPVFAQRCVTLLAPALTRHHADGSNAILVDATLGVGGHAERFLTEFPGLRLIGLDRDPSALDIARTRLMRFADRVTLIHTRYDNLAVALNKFGYAAVESVDGVLFDLGVSSMQLDCAERGFSYAQDVPLDMRMDPWSPVSAADIVNNYDEAALADILRRYGEERFARRIAAHIVRRRAHTPFTSTAELVALLYQAIPAPARRIGGHPAKRTFQALRIAVNDELNSLSNVLPAALDALTVAGRLVVLAYQSLEDRIVKRVFADAVSSRTPAGLPIELPGHGPRFRLLTRGAEHADAAEIECNPRSAAVRLRALQRTQHGVEPQQPTRRGDS
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_MARSD
Sequence: MRHKKSGRKFNRSASHRKAMLRNMVRSLLTYEHIRTTEPKAKELRSSCEKLITLALRNDLHSRRLAYKTLENHGLVKRLFDEIGPRYEGGGGGYTRIIKLAEPRKGDCAPMCIIELTKRAEAPAEEAAATTEAPAEEAQEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RSMG_BORDL
Sequence: MMTNFKFALKNLKVNFTSENIDKLRFYIEKVLLFSDRFNLVSNNVRNFDAMLLHALDSVSGLPIVKDKNPRQVLDVGSGAGFPGIVLALFDRCRKYVLLERSNKKAIFLKMISLELGLENVEVLEHNVEEEQNKYEFITIRAFGDIRKYANILGSILKSGGLIMAYKGKFDKVEFEMSYVKNLFDKVEIKSSELISDKERYFLLLYDYKC
What is the function of this protein?
Specifically methylates the N7 position of a guanine in 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRKA_ARCFU
Sequence: MRIVIAGAGEVGYHLAMSLAPNHDVIIIEKDVSRFERVSELDVVAINGNAANMKVLRDAGVERADVFLAVTGNDEVNLLSGLAAKKVGAKNVIVRVENPEYVDRPIVKEHPLGYDVLICPQLSLAQEAARLIGIPGAIEVVTFSGGKVEMIELQVMEGSKADGKAIADLYLPQNVVIASIYRNGHIEIPRGDTVLRAGDRVAIVSKTEDVEMLKGIFGPPVTRRVTIFGAGTIGSYTAKILAKGMTSVKLIESSMERCEALSGELEGVRIVCGDATDIEFLIEEEIGKSDAVLAATESDEKNLLISLLSKNLGARIAIAKVEKREYVKLFEAVGVDVALNPRSVTYNEVSKLLRTMRIETLAEIEGTAVVEVVVRNTRLVGKALKDLPLPKDAIIGAIVRGNECLIPRGDTTIEYEDRLLVFAKWDEIEKIEEIFR
What is the function of this protein?
Part of a potassium transport system.
What are the official names of this protein?
Trk system potassium uptake protein TrkA homolog, K(+)-uptake protein TrkA homolog.
Protein: DYR_HAEIN
Sequence: MTFSLIVATTLNNVIGKDNQMPWHLPADLAWFRQNTTGKPVIMGRKTFESIGRPLPKRTNIVLSRQLFEHEGVIWKDSFESAVNFVRDFDEIMLIGGGELFKQYLPKADKLYLTQIQTELDGDTFFPQLNWEEWEIEFDEYRKADEQNRYDCRFLILTRK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: ISPD_XANCP
Sequence: MTGSVWAIVPAAGRGTRFGGAVPKQYLHAAGQPLMAYTLAALAAHPAVAGIVVAIAPDDADWPGWTAVHAKPVLTCVGGATRAASVLAGLLALPDGVRADDFVLVHDAARPNLALADLDRLLEIGRGDPVGAILAAPVRDTLKRAGDDGGIDGTEPRERLWRALTPQLFRRHQLIRGLTEASAAGVDVTDEAMAIERLGLRPLLVEGAEDNFKVTTPADLARFEFELANRDRGGASREAERSAMPSAATSVFSGARSAASGSEEV
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: TRM1_PYRCJ
Sequence: MDDYVIRREGKAVFYAPNPKKYDIYSAPVFYNPAMEKNRTLSVLLLKVAGAQMGGGLTVCEPLSGTGIRGIRYVIESGVVGKLILNDLSKEAVHVIQKNLSINGVEADVYNEDANVLLHKLRGQCDVVDVDPFGSPAPFLSAAFRALKNEGIVCATATDTAVLVGRYPRKCLRRYGSVIRKSPFYLEMGLRNLVGYVARIAASEDFAIRPLLSYWEGHYFRTCVYAVKSAKDADDMLQRDVGYVEYRRYRKVTRRQSEYTSGPVWIGELGDPSIAFFMAREGQYSDFLKLLEEEYSVSLPWFYKLPEFAVDGKSPTLEEAMAALRRAGVYAARTHMASDGFKAEATYGEVERVLRRVT
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: PRSE_RHIME
Sequence: MKGWLQQHKPTARRSLSRHLIGVSVLALALVAGVGGWAATTELSSAIVAGGVVIVDDNVKKVQHLTGGIVGELLVKEGDRVEAGQVLIRLDGTTVRANLAIIESTLAQFYARRARLQAERMGAASFEIEEDLAEFIPGTAAAKLIEGEQRLFASRRSALSGMKGQLDSRKAQLADEVEGLTVQLNAIEEALKLIAEELTGVDSLFGQGLVPMQRVTTLKRQRAELEGGRGRHIAARAQARGKSSEIDLQILQLDEDRRSEISKELTDVEAKIAEYEERRTAATDQLRRLDITAPLSGRIYQLAIHTVNGVINPGETLMLVVPEAEDLTVEAKVATHDIDQIRVGQSVEIRFSAFNQRTTPEVEAEVVTVAPDLVTDERTGASYYPLRIRPKAESLAKLKGLSLYPGMPAEVFIKIADRTVISYLTKPLTDQMRHAFRED
What is the function of this protein?
Mediates secretion of glycanase ExsH.
What are the official names of this protein?
Type I secretion system membrane fusion protein PrsE.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IF4E2_SOLLC
Sequence: MADELNKAALEEYKSSSVEDRGEEGEIVGESDDTASSLGKQITMKHPLEHSWTFWFDNPSGKSKQAAWGSSIRPIYTFSTAEDFWSVYNNIHHPSKLAVGADFHCFKNKIEPKWEDPVCANGGKWTMNFSRGKSDTCWLYTLLALIGEQFDYGDEICGAVINVRVRQEKIALWTRNAANETAQVSIGKQWKEFLDYNDTIGFIFHDDAKKLDRAAKNRYSV
What is the function of this protein?
(Microbial infection) Susceptibility host factor required for viral infection (e. g.  potato virus Y (PVY) and tobacco etch virus (TEV)) by recruiting viral RNAs to the host ribosomal complex via an interaction with viral genome-linked protein (VPg).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E-2, eIF4E-2, eIF-4F 25 kDa subunit, eIF-4F p26 subunit, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: FIS1_ASHGO
Sequence: MSNINFLPTIEDAYGALSAEQLDILRQQVLSEGGDIASIQSRFNYAWGLVKSHDAEDQRLGVKLLTDIYKESPMRRRESLYYLAIGCYKLGEYAMAKRYADALVAHEPDNAQARTLKAMVEQKIQTEGLKGAALVGAGLAAVAAAAGFLLRQRRP
What is the function of this protein?
Has a role in mitochondrial fission.  Has a role in outer membrane fission but not matrix separation (By similarity).
What are the official names of this protein?
Mitochondrial fission 1 protein.
What is the protein family that this protein belongs to?
Belongs to the FIS1 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass membrane protein.
Protein: MDEP_STAAU
Sequence: MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
What is the function of this protein?
Involved in multidrug efflux.  Confers low level resistance to drugs such as acriflavine, benzalkonium chloride, chlorhexidine gluconate and ethidium bromide.
What are the official names of this protein?
Multidrug resistance efflux pump SepA, Antiseptic resistance protein SepA, Staphylococcal efflux pump A.
What is the protein family that this protein belongs to?
Belongs to the multidrug resistance efflux pump SepA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AROD_STRP2
Sequence: MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: LOLB_ECO81
Sequence: MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTSDDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: BGAL_ECOLX
Sequence: MTMITPSFPGNSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEARTDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWVGYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATRFNDDFSRAVLEAEVQMCGELRDYLRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGGFVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIELPELPQPESAGQLWLTVRVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPHLTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEATRIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHPARIGLNCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: LIP9_CANAL
Sequence: MLYLILFLIAPIYAGVLLPTKPSIDPFYNAPEGFKNATVGDILQFRKTPKSITGGFVPLNVQNSWQFLVRSEDSFGNPNVIVTTVIEPVNADPSKIASYQVSENAARADCAPSYALQFGSDVSTLATQAETYLLAPLLDKGYYVVSPDYEGPKSTFTVGKQSGQAVLNSIRASLKSGKITNIAEDAKVLMWGYSGGSLASGWAAALQPDYAPELSRNLLGVALGGFITNVTATVEATDDTIFAGIAANVLGGIANEYPEFKSILQNDTNKSSIFNKINNHCLTDSFIKYVGARFLTGDNKVFKSGWNIFKNLVVSKIVKDNGLVYQKQLIPTIPVFIYHGSMDQISPILNPKKTYQNWCDAGISSIEFAEDLTNGHFTESIVGAPAALTWIIDRFSNKPPVDGCQHVVRTTNYEYPNVSSSILDYFKAAMDVVAQQGLGPNIQKDQLEIKSNL
What are the official names of this protein?
Lipase 9.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Secreted.
Protein: Y4166_PAEAT
Sequence: MTILKTTILFVLAAVAEIGGAWLIWQAVREGKAWWWAGLGVVALGIYGFFAAFQPDAHFGRVLAAYGGVFIAGSLGWGMLMDGFRPDRWDVIGAAICIVGVGVIMFAPRPGG
What are the official names of this protein?
UPF0060 membrane protein AAur_4166.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL14_BUCAI
Sequence: MIQEQTILHVADNSGARSAMCIKVLGGSRRRYAAIGDVIKITIKEAIPRGKVKKGEVLKAVVVRTKKGVRRSDGSVIRFDTNACVVLNNNEQPIGTRIFGPVTRELRTEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: SYW_STAAW
Sequence: METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHAITMPQDRLKLRKQTRQLAAIYLASGIDPDKATLFIQSEVPAHVQAGWMLTTIASVGELERMTQYKDKAQKAVEGIPAGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVDRFNSRYNDVLVKPEIRMPKVGGRVMSLQDPTRKMSKSDDNAKNFISLLDEPNVAAKKIKSAVTDSDGIIKFDRDNKPGITNLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEIVKAFLVEFQEKYESFYNSDKLDDILDQGRDKAHKVSFKTVKKMEKAMGLGRKR
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCL18_HUMAN
Sequence: MKGLAAALLVLVCTMALCSCAQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKPGVILLTKRGRQICADPNKKWVQKYISDLKLNA
What is the function of this protein?
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes.  May be involved in B-cell migration into B-cell follicles in lymph nodes.  Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
What are the official names of this protein?
C-C motif chemokine 18, Alternative macrophage activation-associated CC chemokine 1, AMAC-1, CC chemokine PARC, Dendritic cell chemokine 1, DC-CK1, Macrophage inflammatory protein 4, MIP-4, Pulmonary and activation-regulated chemokine, Small-inducible cytokine A18.
What is the protein family that this protein belongs to?
Belongs to the intercrine beta (chemokine CC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: URE2_MYCSJ
Sequence: MVPGEIFFGEGDVEINAGARRLEMEIVNTGDRPVQVGSHVHLPQANAALDFDRTAARGHRLDVPAGTAVRFEPGVAQRVRLVPLGGSREVHGLSLNPPGRLDGAS
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMSA_ANOGA
Sequence: MALLRLVATECRNVLQRGYSTASVPTTKMFIDGKFVESKTNDWIDLHDPATNEVVTRVPKCTQDEMQTAVESSKKAYKTWRQSSILSRQQVMLKLQHIIRNNMSELAKNITKEQGKTLIDAEGDVLRGLQVVEHCCSITSLQMGETVPNIAKDMDTYSYHLPLGVTAGIAPFNFPAMIPLWMFPVAITCGNTSIIKPSERVPGATMLLMEMLNEAGCPPGVVNVIHGAHDAVNFVCDNPDIRAVSFVGSDQAGKYIYERAGRNGKRVQCNMGAKNHGVIMADANKENTLNQLAGAAFGAAGQRCMALSTAVFVGEARNWIPDLVERARKLKVNAGHLPGTDLGPVISPQSKQRINELVESGAKEGAKIVLDGRNIKVEGFEKGNFVGPTIISDVTPNMKCYTEEIFGPVLVCLSVDTIDEAIELINNNPYGNGTAIFTTNGATARKFVNDIDVGQVGVNVPIPVPLPMFSFTGSRGSFLGDCHFYGKQGIKFYTQTKTVTQLWREGDVSHTKAAVAMPTMK
What is the function of this protein?
Plays a role in valine and pyrimidine metabolism.  Binds fatty acyl-CoA (By similarity).
What are the official names of this protein?
Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, MMSDH, Malonate-semialdehyde dehydrogenase [acylating].
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: H12A2_CYRHA
Sequence: MLIKQFSRRPKNMKVQILLAFAALFVLAVGSYASESKKLDLRDASFSAMFSADYQLNPQERGCRYFLGECKKTSECCEHLACHDKHKWCAWDWTIGK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U6-theraphotoxin-Hhn1a 2, U6-TRTX-Hhn1a, Hainantoxin-XII.2, HNTX-XII.2.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 12 (Hntx-12) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CITG_ECOL5
Sequence: MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLNGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTNNARLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMATNGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
What is the function of this protein?
Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.
What are the official names of this protein?
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: LUXS_ECOLU
Sequence: MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: 1FEH3_WHEAT
Sequence: MAQAWAFLLPVLVLGSYVTSLFLPTYITGPLCGGDGGGRSLFLCAQAPKDQDPSPASTMYKTAFHFQPAKNWMNDPSGPMYFNGIYHEFYQYNLNGPIFGDIVWGHSVSTDLANWIGLEPALVRDTPSDIDGCWTGSVTILPGGKPIIIYTGGDIDQNQAQNIAFPKNRSDPYLREWIKADNNPVLRPDEPGMNSIEFRDPTTGWIGPDGLWRMAVGGELNGYSAALLYKSEDFLNWTKVDHPLYSHNGSNMWECPDFFAVLPGNNAGLDLSAAIPQGAKHALKMSVDSVDKYMIGVYDLHRDAFVPDNVVDDRRLWLRIDYGTFYASKSFFDPNKNRRIIWGWSRETDSPSDDLAKGWAGLHTIPRTIWLAGDGKQLLQWPVEEIESLRTNEINHQGLELNKGDLFEIKEVDAFQADVEIGFELASIDDADPFDPSWLLDPEKHCGEAGASVPGGIGPFGLVILASDNMDEHTEVYFRVYKSQEKYMVLMCSDLRRSSLRPDLEKPAYGGFFEFDLEKERKISLRTLIDRSAVESFGGGGRVCITSRVYPAVLADVGSAHIYAFNNGGATVRVPQLSAWTMRKAQVNVEKGWSAI
What is the function of this protein?
Hydrolyzes inulin-type beta-(2,1)-fructans and beta-(2,1)-linkages in branched fructans.  Has low activity against beta-(2,6)-linked fructans.  May play a role as a beta-(2,1)-trimmer during graminan biosynthesis.
What are the official names of this protein?
Fructan 1-exohydrolase w3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 32 family.
Protein: APT_GEOMG
Sequence: MDELKNIIRDIPDFPKKGIVFKDITTLLADAKSFQRMVDLLAHRYVGEKIDKVVGVEARGFILGAALAYKLGAGVVLVRKPGKLPSETFSKTYQLEYGTDSLEIHTDAIRKGEKVLIADDVLATGGTMSAVVEMVRDLGGEIVECCFLAELDFLGGRKKLPDGKVFSLLTF
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_NEIG1
Sequence: MAEQKKIRVTLVKSLIGTIESHRACARGLGLRRREHTVEVLDTSENRGMINKISYLLKVES
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: VG85_BPML5
Sequence: MTEELVNHLFEAIVVENVKRANANMAEPYNHSVYKFHEDRIDRLVTTLADGNEALRDQFYEALFDITWDGVAWAKKVFAEISRDIAEG
What are the official names of this protein?
Gene 85 protein, Gp85.