PharMolix/UniProtQA huggingface dataset:
Protein: PE23_MYCTO
Sequence: MQFLSVIPEQVESAAQDLAGIRSALSASYAAAAGPTTAVVSAAEDEVSTAIASIFGAYGRQCQVLSAQASAFHDEFVNLLKTGATAYRNTEFANAQSNVLNAVNAPARSLLGHPSAAESVQNSAPTLGGGHSTVTAGLAAQAGRAVATVEQQAAAAVAPLPSAGAGLAQVVNGVVTAGQGSAAKLATALQSAAPWLAKSGGEFIVAGQSALTGVALLQPAVVGVVQAGGTFLTAGTSAATGLGLLTLAGVEFSQGVGNLALASGTAATGLGLLGSAGVQLFSPAFLLAVPTALGGVGSLAIAVVQLVQGVQHLSLVVPNVVAGIAALQTAGAQFAQGVNHTMLAAQLGAPGIAVLQTAGGHFAQGIGHLTTAGNAAVTVLIS
What are the official names of this protein?
Uncharacterized PE family protein PE23.
What is the protein family that this protein belongs to?
Belongs to the mycobacterial PE family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS14Z_STRSV
Sequence: MAKKSMIAKNKRPAKFSTQAYTRCEKCGRPHSVYRKFKLCRVCFRELAYKGQIPGVTKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: DADA_PSEU2
Sequence: MRVLVLGSGVIGTTSAYYLARAGFQVTVVDRQPAAAMETSFANAGQVSPGYASPWAAPGVPLKALKWLLQRHAPLAIKATADIDQYLWMAQMLRNCTASRYAINKERMVRLSEYSRDCLDELRLETGIAYEGRSLGTTQLFRTQAQLDNAAKDIAVLEQSGVPYELLDRDGIARVEPALAGVTGILSGALRLPNDQTGDCQLFTTRLAEMAVALGVEFRYGQNIERLDHAGDRINGVWIDGKLETADRYVLALGSYSPQLLKPLGIKAPVYPLKGYSLTVPITNPDMAPTSTILDETYKVAITRFDNRIRVGGMAEIAGFDLSLNPRRRETLEMIVGDLYPQGGDLTQADFWTGLRPTTPDGTPIVGATPFRNLFLNTGHGTLGWTMACGSGRLLADLIARKTPRISAEGLDISRYGNTQENAQHVHPAPAHQ
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: ARNT_WIGBR
Sequence: MDCISTKNNKINKIKFSITIIAFILLYYLIPLNYRDLWQPDETRYAEISREMLQNKNWSIPYLLDIRYFEKPIFGYWINSISQFFFGHNNFSVRFGSFLFTLFSANLIYLFSKKIWKNKILSLNSVIIFLSILLVYIIGTYSVLDSIISFWINLSMISFWLASTSKVKKYKIKNYIILGISIGIGFITKGFISLLIPFISIFIWLFLTKININKTIIHCFFSLLISILIIFPWIYKISYLEKDFIRYFIFIEHIQRFIGENAQHKSPFWYYFPIFIIGCLPWSGFLFSTLNLAWNTRKNKKIEFYLLLWIIVQFCFFSISKGKLPTYILPCFFPLSILIAKNIEKCNLKNKKKLLKINSIINTIVGSTLLIFIILHEKYKFFGCSLYNKNEYYKLILCIFSIFVWIFLNLCIIFNDFKFWRITSLSIIGIAFLFGLYVPEKIIYAKQPQLFIKEVFDDLESSDFIFSNNIGLSTAISWEIKKNNIFIFENKGELEYGLSYLDSKHRFIKKEDFKNWLSKNKEKKISLVMLLPDKHYNWKKFNVPETKKFFQHERLILLKYNF
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase, 4-amino-4-deoxy-L-arabinose lipid A transferase, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y434_BUCAP
Sequence: MNEIISTTILLILIMDPLGNLPIFMTILKKLDAKRRRIVVIREMIIALIVMLIFLFVGEKILTILNLKTETVSISGGIILFLIAIKMIFPSDEGNNGTSSEEEPFLVPLAIPLVAGPSLLATLMLLSHQYLHHMPYLVGSLLIAWFFTIIILLLSGLFLKLFGDKGVNALERLMGLILIMLSTQMFLDGIKAWFKN
What are the official names of this protein?
UPF0056 membrane protein BUsg_434.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y4QE_SINFN
Sequence: MSFFGSEVARPRLFFRGLLGQAGPILITGGRAVADYREAFVGIDVAKLKNAIAVAESGRNGEVRYWGEVEASDAGIRRAIKQITAKFEHVYFCYEAGPTGYGLYRLIRSLGHECIVVAPSLIPRKPGDRVKTNRRDAISLARLLRAGELTAVWVPDEDHEAMRDLVRARTSAVETLRTHRQQVNAFMLKHGRIYPGKRSWTMRYLRWLQEQHFDHPAHQIALQEMVETVIAEFVPHWSLAAVVCALRALRGVDLIAAVTFATEVGDAGRFESPRQLMGYLGLVPGERSTGETTKRIGITKAGNSRVRTLLVECAWTYRYPPRIGKRKLYRLEEVSSSVREIAWKAQTRLTARYRMLSARGKKSTVVCTAVARELAGFMWAIAREARQTTS
What are the official names of this protein?
Putative transposase y4qE.
What is the protein family that this protein belongs to?
Belongs to the transposase IS1111A/IS1328/IS1533 family.
Protein: F90AP_HUMAN
Sequence: MMACRDPKPGAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHMARSTRCPMKCWKAALVPPTLGKKEGKENLKPWKPQVEANPGPLNKDKGEKEERPRQQDPQRKALLHIFSGKPPEKPLPNRKGSTESSVYLRVASGPMPVHTTSKRPRVDPVLADRSATEMSDRGSALASLSPLRKASLSSSSSLGPKERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAISPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPEYLQPPPATTELGPSTSPQMGRRTPAQVSSVDRQPPHSRPCLPTAQACTMSHHPATSHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEVPRVRVPPNVLYEDLQVSSSSEDSDSDLE
What are the official names of this protein?
Putative protein FAM90A26.
What is the protein family that this protein belongs to?
Belongs to the FAM90 family.
Protein: LSPA_CHLCH
Sequence: MKLFFSLALFVVAADQFSKYVALRFLRDANQSISIIPNFFSFTYAENRGIAFGLEPAPPALLLLFTMMISAAVLWYVLRSNNRRLIFLLPFSLILGGGVGNMIDRMVRGYVVDFIYFNLYNGYVGNIYLSLWPIFNIADSAITIGGTMLLLFHRTLFPDDPIA
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS7_CHLAA
Sequence: MPRRGNIERRPIPPDARYNSVLVQKFINKVMERGKKSLAERIVYQALDLAAERLKKPQMEIFEQALRNASPSIEVRPKRVGGATYQVPVEVKSDRRYSLAMRWLLMSARARTGKPMVERLAAELIDAYNNTGTTIKRKEDVHRMAEANRAFAHYGRL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: KTHY_CHLCV
Sequence: MFIVIEGCEGSGKSSLTELLKDRLIAEGKAVVATREPGGSPLGERVRDLILEPSTPSISPYTELFLFLAARAEHITKKIFPALESGNIVICDRFHDSTIVYQGIAEGLGKEYVTSLCHHVVGEKKFLPDLTCLLDIPADEGLRRKQQQKSLDKFEDKPLAYHTKIREGFLSLAEAHPNSYLILDGRQPLEESLNKVMTAYTELALCK
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: NA125_ANEVI
Sequence: MMNRLLVFLMLGAAFMLVVSAIDQDANEDINKRGIPCLCDSDGPSVRGNTLSGIIWLAGCPSGWHNCKKHGPTIGWCCKQ
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation during signal transduction (PubMed:19609479).  Has a strong effect on crustaceans and insects and a weaker effect on mammals (By similarity).  It strongly inhibits D. melanogaster sodium channel (DmNav1) (PubMed:19609479).  It strongly affects the heart sodium channels (Nav1. 5/SCN5A) and weakly inhibits the brain sodium channel Nav1. 2/SCN2A (By similarity).  In vivo, when released into the medium, this recombinant toxin induces impaired swimming, paralysis and death of the crustacean A. nauplii within several hours (PubMed:22048953).  Its effect on zebrafish (D. rerio) larvae is much faster, since it induces paralysis or strong convulsion and impaired swimming, within 10 minutes (PubMed:22048953).
What are the official names of this protein?
Delta-actitoxin-Avd1e 2, Delta-AITX-Avd1e 2, ATX-II, Av2, Toxin 2-5.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Note=In nematocyst, is associated with the tubule prior to discharge.
Protein: PVK2_SUPLO
Sequence: GSSGLISMPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2, SupLo-PVK-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRM5_CRYNJ
Sequence: MLKSLCFVIRPAIVSRPQFRLPTIARLSLRQFQNQPQSVGFFTMAPLETRALALSPSATICPPSRIGTTELDRSAFDLDVQILSAVVEPGMIGKLRSHPSLKDLVLDLPKTKPIVECPAGLAPVAARDVKGLKLLRFHLSKESELPEEAKEVLKGAKALVKEVVRLGYDNWNASEILGACLPTTKSEDIPSSFTTTGHIGHMNLREEWLPFRYLIGQVVLDKNPGLRTIVNKLDTIHAQFRYFDMEVIAGDNDYIATVNESGCSFTFNFSNVYWNSRLHHEHERLISLFPPGCVIADVMAGVGPFAIPAAKKGCYVLGNDLNPESVKWMRENRLRNKVEPTLRVSEIDGFEFIRIAPLEVWTRPFDPAPPPKVSNRQRDREAKEARRKREQAKAAGQPVTETAPMSIPSQEVAIKPHPPQPPKLISHFIMNLPDSAITFLPSYVSCYTPLLAERSFIDEYGGEEEAKRKVEMPMVHCYCFTKEIEIGKAEIDILQRASTNLSFNLTPQVENYNLHHVRSVAPNKDMYCLSFRLPREVAFRHNG
What is the function of this protein?
Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: NBEL1_HUMAN
Sequence: MASRERLFELWMLYCTKKDPDYLKLWLDTFVSSYEQFLDVDFEKLPTRVDDMPPGISLLPDNILQVLRIQLLQCVQKMADGLEEQQQALSILLVKFFIILCRNLSNVEEIGTCSYINYVITMTTLYIQQLKSKKKEKEMADQTCIEEFVIHALAFCESLYDPYRNWRHRISGRILSTVEKSRQKYKPASLTVEFVPFFYQCFQESEHLKESLKCCLLHLFGAIVAGGQRNALQAISPATMEVLMRVLADCDSWEDGDPEEVGRKAELTLKCLTEVVHILLSSNSDQRQVETSTILENYFKLLNSDHSALPNQRRSRQWENRFIALQIKMLNTITAMLDCTDRPVLQAIFLNSNCFEHLIRLLQNCKVFQGQLDCLAISTIQALTAVMNKSPAAKEVFKERIGYTHMLEVLKSLGQPPLELLKELMNMAVEGDHTSVGILGISNVQPLLLLIQWLPELQSHDLQIFISDWLKRICCINRQSRTTCVNANMGIRIIETLDLHSSLHQTCAENLIAIHGSLGSQSVSSEEIRRLLRLLRVDESESVHPYVTPVTRAILTMARKLSLESALQYFNLSHSMAGISVPPIQKWPGSAFSFSAWFCLDQDQLTLGIANKGGKRKQLYSFFTGSGMGFEAFITHSGMLVVAVCTKREYATVMLPDHSFCDSLWHNITVVHMPGKRPFGQSFVYIYDNGQQKVSAPLRFPAMNEPFTSCCIGSAGQRTTTPPPSQIPDPPFSSPITPHRTSFGGILSSASWGGTIEKSKLITKLISAGTQDSEWGCPTSLEGQLGSVIIFYEPLQPPQVKALYLAGPNCLSPWKCQESDMADLPGNILLYYTAKACKNSICLDLSTNCLHGRLTGNKVVNWDIKDIINCIGGLNVLFPLLEQISHFSEGQIPEEKNESTVPESVTPVEGDWLVWTSTKASESRLERNLVATFILIVKHFIQRHPINQGNLIHSHGVATLGALLQKVPSTLMDVNVLMAVQLLIEQVSLEKNMQLLQQMYQYLLFDFRIWNRGDFPFRIGHIQYLSTIIKDSRRVFRKKYGVQFLLDTLRIYYGNGCKYNELSLDDIRTIRTSLYGLIKYFLCKGGSHEEIQSIMGYIAATNEEEQLFGILDVLFSLLRTSPTRGQLFLLLFEPGNADILYALLLNQKYSDRLREIIFKIMEQMLKCTNVYERSKQHIRLREVGYSGLGLLLNEALVNTSLIKNLTHQIINTDPVINFKDLLSVVYISHRAHINVRVAICRKVLQILQFQPDAAHQISQQVGWQDTLVRLFLKAKFENGNTLHKHSRAVLMKDNDKNMSTEDTKKNSDEKTDEEKITSFASANVSSDQWSLEDRHSLDSNTPLFPEDSSVGELSFKSENQEEFWHSNPSHLSLDLSGIDSCEMSDSGSQVPDSLPSTPSPVESTKSFSVHSDRESSITNDMGFSDDFSLLESQERCEEELLQLLTHILNYVMCKGLEKSDDDTWIERGQVFSALSKPGISSELLRPSDEIKLTLLQKMLEWAISENREAKTNPVTAENAFRLVLIIQDFLQSEGLVNSNMWTEKLLEDMMLLFDCLSVCYSESPVWVKLSQIQIQLLLGFIGRGNLQVCAMASAKLNTLLQTKVIENQDEACYILGKLEHVLSQSIKEQTEIYSFLIPLVRTLVSKIYELLFMNLHLPSLPFTNGSSSFFEDFQEYCNSNEWQVYIEKYIVPYMKQYEAHTFYDGHENMALYWKDCYEALMVNMHKRDREGGESKLKFQELFVEPFNRKARQENLRYNNMLKQLSSQQLATLRRWKAIQLYLTCERGPWAKRKQNPIHWKLANVENYSRMRLKLVPNYNFKTHEEASALRDNLGIQHSQPSSDTLLLEVVKQVKVSDMVEDKLDLPEEDITARVNVDEKEEQDQKEKLVLMEDCELITIIDVIPGRLEITTQHIYFYDGSIEKEDGVGFDFKWPHSQIREIHLRRYNLRRSALEIFHVDQSNYFLNFKKEVRNKIYSRLLSLHSPNSYYGSRSPQELFKASGLTQKWVNREISNFDYLIQINTMAGRTYNDLAQYPVFPWILQDYTSEELDLNNPAVFRDLSKPIGVVNEKNAKAMREKYENFEDPMGTIDKFHYGTHYSNSAGVMHYLIRVEPFTTLHIQLQSGRFDCADRQFHSIPATWQALMDNPYDVKELIPEFFYFPEFLENQNQFNLGRLQISKELVNDVILPKWAKSAEDFIYKHRKALESEYVSAHLHEWIDLIFGYKQRGPAAVEALNVFYYCSYEGAVDLDALTDEKERKALEGMINNFGQTPCQLLKEPHPPRLSAEEAVQKPTKIDTSTLNLFQHLPELKSFFIEGISDGIPLLKATIPKNQYRSFMSQGSPELLITISMNYVIGTHGWLPYDRNISNYFTFIKDQTVTNPKTQRSINGSFAPGLEITSKLFVVSHDAKLLFSAGYWDNSIQVMSLTKGKIISHIIRHMDIVTCLATDYCGIHLISGSRDTTCMIWQITQQGGVPVGLASKPFQILYGHTNEVLSVGISTELDMAVSGSRDGTVIIHTIQKGQYMRTLRPPCESSLFLTIPNLAISWEGHIVVYSSTEEKTTLKDKNALHLFSINGKYLGSQILKEQVSDICIIGEHIVTGSIQGFLSIRDLHSLNLSINPLAMRLPIHCVCVTKEYSHILVGLEDGKLIVVGVGKPAEMRSGQLSRKFWGSSKRLSQISAGETEYNTQDSK
What are the official names of this protein?
Neurobeachin-like protein 1, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein.
What is the protein family that this protein belongs to?
Belongs to the WD repeat neurobeachin family.
Protein: UNG_LIMRD
Sequence: MKQLIHNDWWEVLKPQFESAYYAQLHNFLKEEYTHQTIYPEMHHIFEAFEWTPFSKVKVVILGQDPYHGPNQAHGCSFSVLPGVPVPPSLQNIYKELQSDLGCTPVNHGYLKKWADQGVLLLNSVLTVRAGQAYSHRGHGWEQLTDAAIHALSERPKPVVFILWGRAARNKKQLINTKTNIVLESAHPSPLSANRGFFGSRPFSKTNEALQAMGEQPIDWQLPAEPNYR
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RISB_STAMF
Sequence: MARIGIVVSEFNYDITYLMLQKAISHARFLGLEITYVFKVPGTYEIPFAVANLLKRNDVDGVVALGAVIKGATKHDELVASQTARKLMDLMIQYGKPVGLGIIGPGATRMQALERVEDYARRAVEAVAKMINRSKSLEEKKFAGETVFIE
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: TAL_BURVG
Sequence: MTTALDQLKQYTTVVADTGDFQQLAQYKPQDATTNPSLILKAVQKDAYKPILEKTVRDHRNESTDFIIDRLLIAFGTEILKLIPGRVSTEVDARLSFDTQRSIDKGRELIKLYEAAGIGRERILIKLASTWEGIRAAQVLQQEGIKCNMTLLFSLVQAAACAEAGAQLISPFVGRIYDWYKKQAGADWDEAKDGGANDPGVQSVRRIYTYYKTFGYHTEVMGASFRTTSQIIELAGCDLLTISPDLLQKLQDSNDPVERKLSPDALHDKPTERVAIDEASFRFQLNDDAMATEKLAEGIRVFAADAVKLEKLIAALR
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SP2AB_CLOTE
Sequence: MFDNMMKLEILSKSENESFARATVAAFASQLDPTLNELTDIKTAVSEAVTNSIIHGYENKGDKTVKIEAYIKDKELTVIIWDEGIGIENVNLAMQPLYTSRPDLERSGMGFTVMQSFMDELEVKSEKNKGTKIIMKKIFNN
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: TRPM6_MOUSE
Sequence: MQVKKSWIEGVFYKRECNKFIPSSKDPHRCTPGCQICHNLVRCYCGRLIEEHHGLDRAWNLSVTEGHGDEQWSVEKHTVKSPTDTFGTINFQDGEHIHHSKYIRTSWDTKSDHLLHLMLKEWNMELPKLVISVHGGLQNFKISSKLKETFSQGLVKAAETTGAWIITEGINSGVSKHVGDALKAHSSKSLRKIWTVGIPPWGVIENQRELVGKDVVCMYQTLGNPLSKLTTLNCMHSHFILCDDGTVGMYGNEEKLRRNLEKHLSMQKIHTCSRQGVPVVGLVMEGGPNVILWVWETVKNKEPVVVCEGTGRAADLLAFTYKHLEDGGILRPQVKEELFCLIQNMFNFSLRQSKHLFQILMECMVHKDSITIFDADSEEHQDLDLAILTALLKGTSLSISEQLNLAMAWDRMDIAKKHILTYGQHWKPGALEQAMLDALVMDRVDFVKLLIENGVNLHRFLTIPRLEELYNTKQGPTNKFLRHLVQDVKQHTLLSSYRITLIDIGLVIEYLIGGAYRSSYTRKSFRILYNNLYRKHKSVSSFAQGLSQHSLHQRHSLRNRKESSESTLHSQFFRTAQPYKSKEKPEDSQKSKKKSKERQSLSEEPEAAGFIYPYNDLLVWAVLMKRQNMAMFFWQHGEEATVKAVIASILYRAMAREAKESNMVDDTSEELKNYSEQFGQLALDVLEKAFKQNEPMAMKLLTYELKNWSNSTCLKLAVSGGLRPFVSHSCTQMLLTDMWMGRLKMRKNSWLKIIISILLPPMILTLEFKSKAEMSHVPQSQDFQFTWNYSDQGLSNTKESACVKDYDLERGPDEKPDEPLHLDLRNVPQSLPWTRRVYEFYSAPFVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVHEWLVIIYIFTNAIEKVREICISEPSKFKQKVKMWLSEYWNLMETVAIGLFAVGFGLRWGHPPLQTAGRLIYCIDIIFWFSRLMDFFAVNQHAGPYVTMIAKMAANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWRLARDIVFEPYWMMYGEVYASDIDVCSNETSCPPGSFLTPFLQAVYLFVQYIIMVNLLIACFNNIYLDIKSISNKLWKYNRYRYIMTYHQKPWLPPPFILLNHLCLLLRGLCCRPAPQDQEEGDGGLKLYLTKDDLKKLHDFEEQCVEKYFHEKTEGLNCSFEEQIRMTSERVSEMFFQLKEMNEKVSFIKDSLLSLDSQVGHLQDLSAITVDTLKVLSAVDTLQEDEILLANRKHSTCRKRPHSWTNVICAKVLSDMESCGKKKLQYYSMPPSLLRSLARSQLPPSVQRGALVEVTHSKREASHVREEQEEREMEQRTTASGISHVRQAHSKYGQFLLVPSSGKQVPLSLETPPHLFRSSEEAGIDGLVLEHIHQSDLTTHLPQQTPAASHQALVAEHKDQHEAVTQMSDKPAKAEQDLLAFSGTPAPMTVTSLPSRAISMQDEGGYVNWAFSENDETGVFSFKKKWKTCLASTCNSDSNPGGDYFLHTGGRSGLDNSRRLAQSCECPAGPWTQARRSFWINPLCRDKALIKSHSFRFHKEEKLRKTWKNNSHSKSLETRSTWLKAKLLTKTRSLSKKKRKTQGLQVPVITVNACYQSDQLNAEPGETNTTEEFSKKWLSVSNFSQIGLEPYIYQKMKMKEIKRHTTQASDHLRQPQENRDKTPTWNSGSTSLSRSFLTRSPNEVHKISTSLKSPQEPHHHYSAIERNNLMRLSQTIPFTPIQLFTGEEVTIYKLEESSPLTLDKSMSSWSQHGRAAMIQVLSQEEMDGGLRKAMRVISTWSEDDVLKPGQVFIVKSFLPEVVQTWYKIFQESTVLHLCLREIQQQRAAQKLIYTFNQVKPQTIPYTPRFLEVSLVYCHSANQWLTIEKYMTGEFRKYNNNNGDEIAPTNTLEELMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEDKQSRGMVFGPANLGEDAIRSFIAKHRCNSCCGKLRLPDLKRNDYSLSRTHCNLGFGQTIEPTEELPERDKNRSSLEDHTRL
What is the function of this protein?
Essential ion channel and kinase.  Crucial for magnesium homeostasis.  Has an important role in epithelial magnesium transport and in the active magnesium absorption in the gut and kidney (By similarity).
What are the official names of this protein?
Transient receptor potential cation channel subfamily M member 6, Channel kinase 2, Melastatin-related TRP cation channel 6.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM6 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TEP1_YEAST
Sequence: MREEGSELEMEKGFLKWKPVNLMKKILSLPMKKTKNDIGLRLDISYILVNLIVCSYPVNTYPKLLYRNSLDDLILFLTVYHGKGNFRIFNFRGEKEDSDYKDNDLIGIAAKFESKDFEIQELRSTLINDGKIPISPIDLETRTLVEEETNNVICERIGWLDHFPPPFELLEEIVDGIENYLSVSKNRVAVLHCRMGKGRSGMITVAYLMKYLQCPLGEARLIFMQARFKYGMTNGVTIPSQLRYLRYHEFFITHEKAAQEGISNEAVKFKFKFRLAKMTFLRPSSLITSESAIVTTKIQHYNDDRNALLTRKVVYSDIMAHECGGNMTFIFGRDYLTLENDCRIEFTLGTSKSKAASSIISWTSCASCWLNIYLETLMHIIKDDSSPDYFQVERLKRDEMLGTTISWQELDGFGELSTHGLKLFQALKLEWEII
What is the function of this protein?
May act as a phosphoinositide 3-phosphatase by regulating PtdIns(3,4,5)P3 levels.
What are the official names of this protein?
Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1.
Protein: RCAN1_RAT
Sequence: MHFRDFNYNFSSLIACVANGDVFSESETRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPLSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEEEEEEEEEMERMKRPKPKIIQTRRPEYTPIHLS
What is the function of this protein?
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A.  Could play a role during central nervous system development.
What are the official names of this protein?
Calcipressin-1, Down syndrome critical region protein 1 homolog, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1.
What is the protein family that this protein belongs to?
Belongs to the RCAN family.
Protein: CABM1_MACCH
Sequence: VRTPVTVQTKVDNIKXY
What is the function of this protein?
Hydrolysis of carbamoyl and sulfocarbamoyl esters of paralytic shellfish toxins.  Ester hydrolysis is unaffected by the presence or absence of a hydroxyl moiety at the N-1 postion of the substrate toxin but is significantly affected by the stereochemistry of sulfate esters at C-11 of the substrate toxin.
What are the official names of this protein?
Carbamoylase-1, Carbamoylase I.
Protein: KTHY_WOLPP
Sequence: MFITFEGIDGSGKTTQSELLANYFKQIHGENNVVLTREPGGTDFAEKIRGSLLKDNIDPISELLLFTSMRYEHMKELILPALKEGKTVICDRFIDSTIAYQGYGLGVDLSLIRDLHKLVEIKYPDITFILDIDVQVGLSRAKDKNKYEEMSIDFYHKIRKGFQEIAIKESNRCNVITGIADKDNNKVYSEIIDVIRKKKKGMQPL
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: SL9B_PROFL
Sequence: MGRFIFMSFGFLVVFLSLSGTAADCPSDWSSYEGHCYKPFSEPKNWADAENFCTQQHAGGHLVSFQSSEEADFVVKLAFQTFGHSIFWMGLSNVWNQCNWQWSNAAMLRYKAWAEESYCVYFKSTNNKWRSRACRMMAQFVCEFQA
What is the function of this protein?
When linked to subunit A of IX-bp, anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factor IX (but not to factor X) in the presence of calcium with a 1 to 1 stoichiometry.
What are the official names of this protein?
Snaclec coagulation factor IX/factor X-binding protein subunit B, IX/X-bp subunit B.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: GATA_NITSB
Sequence: MITLKEALSKPKGELQEIKDELKKRAQEQSEINAYVALDESGEGVPVAIKDNIQVDGWEVTCASKILKGYIAPYDATVIQKLRANGLAPFGRTNMDEFAMGSTTETSCYGKTLNPKDTSRVPGGSSGGSAAAVAAGIAIAALGSDTGGSIRQPAAFCGVVGMKPTYGRVSRYGLAAYGSSLDQIGPMTQNVEDAAILYNIIAGSDAKDSTSARIECKPVVPDPKRKLKIGVVPNYVKDASGAIQKAYDKAIEALKQEGHEIIEISLMDAKYDIASYYITAMAEASTNLSRYDGVRYGYRAEAKNLKEMYLKTRSEGFGEEVKRRILLGTFVLSSGYYDAYYIKAQKARHIIKDEYNKVFEKVDLILSPVAPDVAFEFGAMKTPLEMYLSDVYTIGVNLAGLPAISLPVDEHEGLPVGLQLIGKAFDEQTVFDGAMSLENALK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: AQY1_YEAST
Sequence: MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISRDTLRDHFIAAVGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKRETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKGETSSSSAVAEV
What is the function of this protein?
Water channel required to facilitate the transport of water across membranes.  Involved in sporulation, freeze tolerance and osmotolerance (By similarity).  Is non-functional in most laboratory strains.
What are the official names of this protein?
Aquaporin-1.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: Y1726_BACC7
Sequence: MKVIAVTGYKPFELGIFKNDHPGVECIKKALRRKLTAFVEDGLEWVIISGQLGVELWAAEVVFEIQVEYPDLKLAVFTPFLEQEEGWKEDNREYYEFILSQADHVDSITKRKYESPEQFKLKNQFFIEKSDALLAVYDEEKPGSPKYIVEAAKKKGEIENYHSYFILFSDLQDIIEEEQWNNAE
What are the official names of this protein?
UPF0398 protein BCAH187_A1726.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.