PharMolix/UniProtQA huggingface dataset:
Protein: RL16_GEODF
Sequence: MLMPKKVKHRKQMKGRMSGTPQRGVSLAFGDYGLQATECGWLDSRQIEAARIAMNRYIKRGGKIWIRIFPDKPLTAKPAETRMGKGKGSPDSWVCVIKPGRILYEMEGVTEEVAREAFRLAAHKLPIPTKFTSRKDANEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: BETI_ECO24
Sequence: MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAALIDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD
What is the function of this protein?
Repressor involved in the biosynthesis of the osmoprotectant glycine betaine.  It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator BetI.
Protein: RISB_STAA3
Sequence: MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAVITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: ARGC_BRUA2
Sequence: MKPKIFIDGEHGTTGLQIRTRLAERDDLEVISIPEAERRNKDLRADYLRAADIAILCLPDDASKEAVSLLEGHNSTRIIDTSTAHRVHPDWAYGFAELAKGQRERIAEARLVANPGCYPTGAIALVRPLRDAGLLPADYPVSVNAVSGYTGGGKQLIAQMEDRNHPDYLAANNFLYGLPLKHKHVPELQLHGRLDRRPIFSPSVGRFPQGMIVQVPLFLSELEGSPSLAKVHAVLTEHYAGQDIVEVVPLEESAKLPRVDAEELAGKDGMKLFVFGTEDHGQVNLVALLDNLGKGASGAAVQNMNLMLGK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARNB_ECO24
Sequence: MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
What is the function of this protein?
Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N).  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase, UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-Ara4O aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily.
Protein: TGT_THET8
Sequence: MDPFRFQVEARAGRARVGRLFTPHGAVETPLFMPVGTAGSVKGLMPKDLEAIGSQVLLTNTYHLLLRPGPERVRALGGLHGFAGWKGPWLTDSGGFQVMSLGHMRRIDEEGVVFQSHLDGRLIKLTPERSIAVQEALGADLIMAFDECPPYPSPREYLEASLERTLRWLERSLKAKTRPDQALFGIAQGGTDPELRRRSTLETIRFDLPGYAIGGLAVGEPKEAMFAMVELSTRLLPEDRPRYLMGVGHPEDLVAAMGLGVDLFDCVYPTRTGRFGSALVPEGRLNLKNARFLEDRRPLEEGCDCYTCQTFGRAYLAHLVRAGEMLGGILLSLHNLRHLHRLTEAARQAIREGRYGDFAREFARRRFGREVPPWFREALAAGGHG
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: CIDA_BACLD
Sequence: MKTFIKGLGQVALLFLFARFMNLIVEVLHINIPGSILGIIVIFALLHFKIIKLEWIEIGALWLLAELLLFFVPSAVGIMNYGDILAEFGTSIILVVLISTFVVMVSTGMLTQLIAKRKERKKTCSSDA
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10_PROM5
Sequence: MGRTIENKQKIVTELKSLLDDSEMAVVLDYKGLTIKEMSDLRSRLQTNKGICKVTKNSLMRKAIDGNSNWTDLESLLTGTNAFVLIKEDVGGAVKAIQSFQKETKKSETKGALFEGRLLSQSEIKEIASLPSREVLMAKIAGALNGVATKIAISINEVPSGLARSLKQHSEKSES
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CYB_BOSGF
Sequence: MTNIRKSHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGVCLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLYMHVGRGLYYGSYTFLETWNIGVILLLTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITAIAMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGTLLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILILIPLLHTSKQRSMMFRPLSQCLFWTLVADLLTLTWIGGQPVEHPYITIGQLASIMYFLLILVLMPTAGTVENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PGK_BACCN
Sequence: MNKKSIRDVDLKGKRVFCRVDFNVPMKDGKITDETRIRAALPTIQYLVEQGAKVILASHLGRPKGQVVEEMRLTPVAVRLGELLGKDVKKADEAFGPAVQEMVAAMNEGDILVLENVRFYAGEEKNDAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAVAGFLMEKELEVLGKALSNPDRPFTAIIGGAKVKDKIGVIRHLLDKVDNLIIGGGLAYTFVKALGHEIGLSLCEDDKIELAKEFMALAKEKGVNFYMPVDVVITEEFSETATTKIVDIDSIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFSNGTRAVGQALADAEGTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_PROM3
Sequence: MSSSSSGNSRHFGRVAPVVLAILDGWGHREELEHNSIRSAETPIMDALWHAYPHTLIEASGAAVGLPDNQMGNSEVGHLTIGAGRVIRQELVRISETVQTGRLGQTPALIALAERLRKSDGTLHLLGLCSDGGVHSHINHLCGLLHWAAAAGLNKVALHLITDGRDTPTQSASNYLHQIEDAINASGVGELASLCGRYWAMDRDHRWERTIRAYEVLTDPNQSISRVTAEDVLSASYANGTTDEFLEPTRLSNNYFKDGDGLVMFNFRPDRARQLVQSLTLPDFDGFPRANQPSLDVVTFTQYEHDLPVAVAFPAESLDDLLGQVVSEHGLRQYRTAETEKYPHVTYFMNGGIEQPLAGEERHLVPSPRVATYDLAPAMSADTLTESCVKAIESGVYSLVIINYANPDMVGHTGVMGAAQEAISTVDRCIGRLLDSTGRMGGTLLITADHGNAELMQGSDGQAWTAHTTNPVPVILVEGEKRKLSGYGNDIQLRAGGGLADIAPTLLQLLDLPKPDAMSGLTLIQAIESPTPSARLPQPV
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RRAGB_MOUSE
Sequence: MEESDSEKKTEKENVGPKVEPPLGEPEGSLGWAMPNAAMKKKVLLMGKSGSGKTSMRSIIFANYIARDTRRLGATILDRIHSLQINSSLSTYSLVDSVGNTKTFDVEHSHVRFLGNLVLNLWDCGGQDTFMENYFTSQRDNIFRNVEVLIYVFDVESRELEKDMHYYQSCLEAILQNSPEAKIFCLVHKMDLVQEDQRDLIFKEREEDLRRLSRPLECSCFRTSIWDETLYKAWSSIVYQLIPNVQQLEMNLRNFAEIIEADEVLLFERATFLVISHYQCKEQRDAHRFEKISNIIKQFKLSCSKLAASFQSMEVRNSNFAAFIDIFTSNTYVMVVMSDPSIPSAATLINIRNARKHFEKLERVDGPKQCLLMR
What is the function of this protein?
Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.  Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form.  In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB.  Involved in the RCC1/Ran-GTPase pathway.
What are the official names of this protein?
Ras-related GTP-binding protein B, Rag B, RagB.
What is the protein family that this protein belongs to?
Belongs to the GTR/RAG GTP-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Lysosome.
Protein: GR58A_DROME
Sequence: MLLKFMYIYGIGCGLMPAPLKKGQFLLGYKQRWYLIYTACLHGGLLTVLPFTFPHYMYDDSYMSSNPVLKWTFNLTNITRIMAMFSGVLLMWFRRKRILNLGENLILHCLKCKTLDNRSKKYSKLRKRVRNVLFQMLLVANLSILLGALILFRIHSVQRISKTAMIVAHITQFIYVVFMMTGICVILLVLHWQSERLQIALKDLCSFLNHEERNSLTLSENKANRSLGKLAKLFKLFAENQRLVREVFRTFDLPIALLLLKMFVTNVNLVYHGVQFGNDTIETSSYTRIVGQWVVISHYWSAVLLMNVVDDVTRRSDLKMGDLLREFSHLELVKRDFHLQLELFSDHLRCHPSTYKVCGLFIFNKQTSLAYFFYVLVQVLVLVQFDLKNKVEKRN
What is the function of this protein?
Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates.
What are the official names of this protein?
Putative gustatory receptor 58a.
What is the protein family that this protein belongs to?
Belongs to the insect chemoreceptor superfamily. Gustatory receptor (GR) family. Gr22e subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CUCS_CUCPE
Sequence: MWRLKVGAESVGEEDEKWVKSVSNHLGRQVWEFCADAAADTPHQLLQIQNARNHFHHNRFHRKQSSDLFLAIQYEKEIAKGAKGGAVKVKEGEEVGKEAVKSTLERALGFYSAVQTRDGNWASDLGGPLFLLPGLVIALHVTGVLNSVLSKHHRVEMCRYLYNHQNEDGGWGLHIEGTSTMFGSALNYVALRLLGEDADGGDGGAMTKARAWILERGGATAITSWGKLWLSVLGVYEWSGNNPLPPEFWLLPYSLPFHPGRMWCHCRMVYLPMSYLYGKRFVGPITPKVLSLRQELYTIPYHEIDWNKSRNTCAKEDLYYPHPKMQDILWGSIYHVYEPLFTRWPGKRLREKALQAAMKHIHYEDENSRYICLGPVNKVLNMLCCWVEDPYSDAFKLHLQRVHDYLWVAEDGMRMQGYNGSQLWDTAFSIQAIVATKLVDSYAPTLRKAHDFVKDSQIQEDCPGDPNVWFRHIHKGAWPLSTRDHGWLISDCTAEGLKASLMLSKLPSTMVGEPLEKNRLCDAVNVLLSLQNDNGGFASYELTRSYPWLELINPAETFGDIVIDYPYVECTAATMEALTLFKKLHPGHRTKEIDTAIGKAANFLEKMQRADGSWYGCWGVCFTYAGWFGIKGLVAAGRTYNSCLAIRKACEFLLSKELPGGGWGESYLSCQNKVYTNLEGNKPHLVNTAWVLMALIEAGQGERDPAPLHRAARLLMNSQLENGDFVQQEIMGVFNKNCMITYAAYRNIFPIWALGEYCHRVLTE
What is the function of this protein?
Oxidosqualene cyclase involved in the biosynthesis of the highly oxygenated tetracyclic triterpenes cucurbitacins.  Converts oxidosqualene to cucurbitadienol and does not produce lanosterol.
What are the official names of this protein?
Cucurbitadienol synthase.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: RS10_BRAPL
Sequence: MKEQKIRVKLKAFDIELIDQSAQSIVASVKKTGARVSGPIPLPTSIRKVTVIRSPHVNIKSREQFEMRVYKRLIDIFDVTPQTTESLKKLALPAGVDVQLK
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: GPDA_SALCH
Sequence: MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATLEHDRCNVAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFSDVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDETFADDLQQLLHCGKSFRVYINADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGAQDKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKEELSRH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPP3_VERA1
Sequence: MASGDNVDYEAVMVDEFDALNIEVRVSAGPSSSVPGAALSAPRCPGMRALPLKAPVMSTPVPAAAPLPTPPAVDDGPSAVGVGNVPPAVDDVPSAVDDVVIQKETTKYSAKLHAAKVADELKASAGLVFLPGEPSRTYEYSDMGPAFSSNAATSSTSPASTSLTPRKVLYNGRVPSIKDVLAASDVDEVRHMQDLPAFLHAYAHQHDKATVYLLDASQSHPALVDNARVHIDTAALRPAMDEARVTKTAHEIALIREANAVSSAAHRAVMRHIRRFASERQVAALFTAECTVRGAPTQAYAPIAGSGPNAATLHYGANDEPLAGRHVLVLDAGCEVNCYASDVTRTLPLGPTGHFTPEARHIYDLVERMQEACVAAVAPGLLYYSLHLKASAIALRGLLRLGILKGDEKAIWAAGTVAAFFPHGLGHHIGLETHDVTGRDRLLLAAGEREPRAKRDAVSAEMLVGLAAAVATGPPYRGKQMLRPGMVVTVEPGIYFNKDYIEGYFLREDKHRAFIDRDVLARYYPVGGVRIEDCILVTDDGYENLTKAPKGEDMLRIIRGEAQ
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase PEPP, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: RL7_LEPCP
Sequence: MAFDKDAFLTALDSMTVLELNDLVKAIEEKFGVSAAAMAAPGAGAGAAAAVVEEKTEFNVVLLDAGAQKVSVIKAVRELTGLGLKEAKDLVDGAPKNVKEGIAKADAEAALKKLLEAGAKAEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: EDSM_MAIZE
Sequence: MAPSNIVVQSSSTPPVAGGDEEFAPSVWGDFFVTYAPPVSQASEQRMSERAELLKAQVCQAFDAASMDVAGLVTYVDTLERLGLDNHFRDLIGAALERIGAEELPEHGGGLHIVALRFRLLRQHGIWVSTDVFDAFREDAGGFCSSLCSDDPRGLLSLYNAAHMAVPGEVVLDDAIAFARGRLLDIISKGEVRSPVSEQITRALDIPLPRFTRRLETMHYIAEYEHEEAHDGLLLELARLNFVLVRALHLRELKDLSLWWRELYNTVKLPYARDRMVEIYFWTCGMLHEEEYSLARMFFAKTFGMVSLMDDTFDVHATLDECHKLKEAMQRWDESEVSILPEYLRLLYIKTLSNFKEFEEILEPNKKYRMAYTKEAYKLCSKNYLKEAIWSNQKYQPSFKEHEELSIMTSGLPMLTILTLMGFGDEATPEAFEWVSSVPEMVRAGSQVTRFLNDLSSYKLGKNKKDMPGSVETYMVENGLTGDEAAAAIAALLENRWRILNQTRMEIDHTLLPAVQVVVNMARANEIIYLHGRDAYTFGADLKDLVTTLFLKQVLPL
What is the function of this protein?
Component of the volatile terpenes biosynthesis pathways (By similarity).  Dihydroxylated sesquiterpenoid synthase that generates dually hydroxylated products directly from (E,E)-farnesyl diphosphate, primarily eudesmane-2,11-diol, along with two closely related structural isomers (By similarity).
What are the official names of this protein?
Eudesmanediol synthase, ZmEDS, (+)-germacrene D synthase, Terpene synthase 17.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAA_STAHJ
Sequence: MSEQEIWKKVLEVAESEISKSTFNTFLKDTELKEIRDNVAIIFVIHEFYAEWLNSNYKEVIQTIMKDVIGYEVEPKFFTAEQLAELDETSRKSNTPSEPQRQIIEYGHEGTDQFNTHNTFDTFVIGPGNRFPHAASLAVAEAPAQAYNPLFIYGGVGLGKTHLMHAIGHHVLSNQPNAKVLYTSSEKFTNDFIKSIRNNEPEAFREKYRNIDVLLIDDIQFIQNKEQTQEEFFHTFNELHQNKKQIVISSDRPPKEIAKLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEENLEIPAEALNYIANQIQSNIRELEGALTRLLAYSKLQGRPITTELAAEALKDIIQVPKSKKITIQDIQKVVGHYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKIAKDIKADTIFKQEVEDLEKEIRNQ
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_ACIB5
Sequence: MLLWLFEQLAGYHSSFQVVRYLTLRSLLSVLTSLTIGLVLGPIMIRKLQALKYGQAVSSFAPENHAKKMGTPTMGGILILLSIGISTLLWADLSNPYVWIVLGVMVVFGAVGWADDWIKIRYKDNAGLPARKKFFWTSVASLGAGIALYLIATQQSNAEYTANMLDLLIPFFKNLSIPLSIVPLGLAFIVFTYLVINGASNAVNLTDGLDGLAIMPVVMVATGLGVFAYLSGDIRFANYLHIPYVKYTSELVVICSAMIGAGLAFLWYNAHPAQVFMGDVGALALGAMLGTIAVMVRQEIVFAIMGGVFVMEAVSVFLQIGSLRMRNKRVFLMAPLHHHYEKQGWKETQVVIRFWIITIMLVVLGLMTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL31_HALWD
Sequence: MSTSDFEERVVTVPLRDVSAVPTHERAGRAMTLIREHLAQHFRVDESDIRLDPSLNETVWARGSQNPPSKLRVRAARFDEDGESIVEAEPAE
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: FABZ_HERA2
Sequence: MLTVEDILAILPHRPPFLLVDRILEIEDGLRAVGLKNVTMNEPFFVGHFPGRPVMPGVLIVEALAQVGAVIILRQPEYVGKIVMFAGIDDFRFKRPVTPGDTLKLEVSLDKMRRRIGKGQAKATVDGTVVAEGGLMFAIVD
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UNG_LACH4
Sequence: MAKELIGNDWDKVLDPVFASDKYHELHNFLKEEYSNKRIFPDMYHIFTAFKLTPFNKTKVVILGQDPYHNPGQANGMSFSVMPGTPLPPSLRNIYKELYDDVGVRPVNHGYLKKWADQGVLLLNAVLTVPYAHANGHQGKGWEDVTDTAIKALSERGKVVFILWGRFAQNKIPLIDQSKNFIIKSSHPSPFSADRGFFGSRPFSRCNTALLNFGETPIDWQLSETVNKSDLA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU5M_MOUSE
Sequence: MNIFTTSILLIFILLLSPILISMSNLIKHINFPLYTTTSIKFSFIISLLPLLMFFHNNMEYMITTWHWVTMNSMELKMSFKTDFFSILFTSVALFVTWSIMQFSSWYMHSDPNINRFIKYLTLFLITMLILTSANNMFQLFIGWEGVGIMSFLLIGWWYGRTDANTAALQAILYNRIGDIGFILAMVWFSLNMNSWELQQIMFSNNNDNLIPLMGLLIAATGKSAQFGLHPWLPSAMEGPTPVSALLHSSTMVVAGIFLLVRFHPLTTNNNFILTTMLCLGALTTLFTAICALTQNDIKKIIAFSTSSQLGLMMVTLGMNQPHLAFLHICTHAFFKAMLFMCSGSIIHSLADEQDIRKMGNITKIMPFTSSCLVIGSLALTGMPFLTGFYSKDLIIEAINTCNTNAWALLITLIATSMTAMYSMRIIYFVTMTKPRFPPLISINENDPDLMNPIKRLAFGSIFAGFVISYNIPPTSIPVLTMPWFLKTTALIISVLGFLIALELNNLTMKLSMNKANPYSSFSTLLGFFPSIIHRITPMKSLNLSLKTSLTLLDLIWLEKTIPKSTSTLHTNMTTLTTNQKGLIKLYFMSFLINIILIIILYSINLE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 5, NADH dehydrogenase subunit 5.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y9776_DROME
Sequence: MDEDSATIQLGDRRLGNAVDHDLLPGPPGVDEKSGNENCEPRSSGSGKRGKSNSRRRSTSRGRSDSRNTSPSNTRRRHSLSRSLTPPRRRYDSPDYGRYSRRRFDRDRRRSPERRRSPPRRGRRYGRSRSRSMSPRRGGRWSPKKKPSSPPVPPPHGGPHPQMTPGYGAMAAHIYGSYVAPPDVYGHQYGIPPNSFPPQGPGYGIPGAPPDQSSFGSGYGPPPTSAWDVNVYGQQVWINQPISGVQPSASDSLIQPQKARETLSGKTIGEEQSVPALEGAGLTPQDAVAQEAEKQKDELKKQRANYVKKVSLLKKEMKVLKDQREDLAAGDAPPSPTTKNFIEENDRLQMQIKKKLDTIENVIDMLNGIIGYEEVEDEPSNQKSHGKTQPEQQDSRSHSSSESSADSSESSSSSSTASDSSSDNEDGEGAGGAVGSPTNRLKHRAIKSMKSKQLHGEMKAVPTQAQNYNFVFFDPEQHWCESCGVFPKSARDYLKHLHAEEHMNRETIETPWHVGIDHDPFPTFENAPARRVPVRGMQFLVPANAWFCKLCSVWIGDLHCASAHLKSRLHSNKYQQFLNQNPNYEIEWQTNRERAMNQQKDHDDAKNKKSKKDEDKASKKRKKKGGDKKKKKRKHGKKSKRSTIDANSTSSSSDSSSSEEENGQQPKKGRTEQQPICQSDKSTNAASIRVAMRKQESTPTNLKPEVPCQPVVPPPPPIIKDSTIPSERGKWTAASVEDQSKDQKNRDDTMLKQWNNVQPVISESEKKLLEQLKGRLKNKGARDQNNHKAVPTEANDEKFRRGGGRHSRSRSKRRSYSRSISRGRDRDRRDRERDRDRGRRRRSRSRGRHFSRSPIRSSRRSRSRQGRSRRSRSRSIERVERPVVKHSEFRPRTVPERKQTDIKRDKKDAESKSKSSKPSNNSLPGGKKLPFIGKMPVFKKQSVPSFNYDASAVYTNGCLEAPPPPPPPLGGATSQIAVRQQAPTAAQIQMAMMEDAFGNAPPFHPDAGMMVDYDELMPDPVQFANLMTSCPPPPPPGEGSEGDAHGPEDGDQHDNENREDVLPPGIDEAESALVPHPLDAAAQSRDGELPKDLVEALDIIFPSDVAILEASNGNSEKQEDVTITTIVEDDAVLSVIHLQDLAKEGIHLVTINEAEVPKKSHIQTSEKIEKLQDLNGKSDDGVNIKLIDAEDIPMPNSPPAEPSFDEETKSKALQKQADISEIPEPAVSPSDSEKLRRQSELDELAMLGIDRSDMAAQYAL
What are the official names of this protein?
Zinc finger matrin-type protein CG9776.
What are the subcellular locations of this protein?
Nucleus.
Protein: FIS_GLAP5
Sequence: MLEQQPTQNPLTVSMLNAQAQQVDRPLRENVKQAVRNYLRNLDGQDPTELYELVLSEIEHPMLDMVMQHTRGNQTRAATMLGINRGTLRKKLKKYGMG
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.