PharMolix/UniProtQA huggingface dataset:
Protein: RPPH_AZOVD
Sequence: MIDPDGFRPNVGIILTNDIGQVLWARRINQDAWQFPQGGIDARESPEEALFRELNEEVGLEPQDVRILACTRGWLRYRLPQRLVRSHSQPLCIGQKQKWFLLRLLSDEQRVRMDLTGKPEFDGWRWVSYWYPLGQVVAFKREVYRRALKELAPRLLARD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: QUEH_STAES
Sequence: MIEANQILAKMKNQKINYDKVLRKIISQWERDGERPKILLHSCCAPCSTYTLEFLTQYADIAIYFANPNIHPKSEYLRRAKVQEQFVNDFNNKTGASVKYIEAEYEPHKFMKMAKDKGLTEEPEGGLRCTACFEMRLEIVAKAALEHGYDYFGSAITLSPKKNAQLINELGMDVQNIYNVKYLPSDFKKNKGYERSIEMCNDYNIFRQCYCGCVFAAMKQGIDFKQINKDAQAFLQQF
What is the function of this protein?
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
What are the official names of this protein?
Epoxyqueuosine reductase QueH, Queuosine biosynthesis protein QueH.
What is the protein family that this protein belongs to?
Belongs to the QueH family.
Protein: SSRP_LACPL
Sequence: MAKQHGKHPDTALAQNRKARHDYAVEETYEAGIALTGTEIKSVRDRRVNLKDGFVQVRNGEAWMQNVHISPFKEGNRYNVDPLRSRKLLLHKKEISKLGAATMTKGVTIIPLKMYLKHGFAKVLIGVAHGKREYDKRQDIKKREQQRQIDRVMKHY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: IHOG_DROPS
Sequence: MSPLTSSLLLFSLLTSSLEAIPVLQPSFPPSSPSPAPSPGVRILRAPESIVAPLGDEVVFECETSLQPEGFEWSYRRWPNAANSNGSVGASRFKYLKSGNGKLNVTQETAISRLRVLVRPDTVGEYRCIGWFGPLVVTSTTARLELANTSVKGRQETHLQWRVAPGNSVLWSCGQQVHSNPSASWSYYRNGVEIKPELAATNGNLFLTNVSTASAGKYTCLATNPASGARIEISSSMVLEVLSGRGSQNKAPHLLSGQPTSQAVTIREGSTLLLLCPGVGSPTPTAVWSSPDVVEAIHNKRTRVLNHGLEISNVQGHDTGTYICYLDNGVRPTLEHFINVTVEVPPRITRPPWADLTNEGERMQLECEATGVPAPELYWLLNGESSINDTEAEQLPNGYLVLHSVQKRHAGYVQCFARNRLGEQSAGTLLQVNPKQIQSEPRETGSGGGFGSHRSMKPVNHGQKPTKMIPPSPPNVTRLSDESVMLRWHVPRNDGLLILFFKVQYRMISEGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPQRTYRFRILAVYSNNDNKESNTSAKFYLQPGAALEPMPVPELLEIEEYSETAVVLHWRLDSDADEHLITGYYAYYRPSSSAGEYYKATIEGAHARSFQIATLEAATIYEFKLQSFSAVSASEFSALKQGRTQRPKASTTEEPTIQGIGDRDTTTPSHNETFSMSPMLTGTIGGGALLLILLVSAFLCMCRRRSPRGRGQTQNKPRMAELREDFVPLGSCSPNKQRQRTRHIHITLNPLAQQQQQQLDEKNPPGLETDNDMAYFQRQPTYEYDPGLRRMSSSSLRRSQRTLERAGGANSGGNNGGNNNNLNQSSEAGTADGPCMQSSSKPGRVIMKRPRLSSRSENLSSGSLNSVGV
What is the function of this protein?
Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc).
What are the official names of this protein?
Interference hedgehog.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IHOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: LPXD_BURPS
Sequence: MALTLEALAARFGGEIVGDGRCEVGALAPLDQAGPRQLAFLANPKYLAQVETTGAGAVLIAPGDLEKLGAAAHGRNFIVTPNPYAYFARVAQMFIDLAAPPRAAGVHPSATIDPAAQVAASAVIGPHVTVEAGAVIGERAQLDANVFVGRGTRIGDDSHLYPNVAIYHGCTLGPRAIVHSGAVIGSDGFGFAPDFVGEGDARTGAWVKIPQVGGVKVGPDVEIGANTTIDRGAMADTVIDECVKIDNLVQIGHNCRIGAYTVIAGCAGIAGSTTIGKHCMIGGAVGIAGHVTLGDYVIVTAKSGVSKSLPKAGIYTSAFPAVEHGDWNRSAALVRNLDKLRDRIKALETALAAREGDAGGA
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: ISPE_CERS1
Sequence: MTEAFARAKINLTLHVTGQRPDGYHLLDSLVVFADVGDRVRAEPAEALSLAITGPQAANLPVADDNLVLRAARTLGGQGARLTLEKHLPVASGIGGGSADAAAALVALARLWQVPLPDPAAVLKLGADVPVCLEGRAVRMAGVGEILTPLAAPLPEAWLVLANPGVSVPTPPVFKALARRDNPPMPDDLPGWPTVESLAAFLATQRNDLEPPAIALAPEIARTRAALAAQPGCLLARMSGSGATCFGLFAAEEAARAAAEAIGAEHPGWWVAPARMVG
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: EFP_RHOP5
Sequence: MRVIASSIRKGNVIEQDGKLYVVLTAENIHPGKGTPVSQIEMRRISDGVKISERYKTTDQVEKATIEDSNFTFLYEDADGFHFMNPESFDQVQVPKEVVGNAAPYLAENMSVKLSMHDTTPVAIQLPQRATLEVVDTEPVTKGQTASSSYKPAMLSNGVRTAVPPHIGVGTRIVVMTEDGSYVERAKD
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLME_ACIB3
Sequence: MATRITNQKLSKSSRAWMREHLDDPFVKKAQKEGYRARAAYKLLEIQEKYKLIKPGMTVVDLGAAPGSWSQIAGKLVGSKGLVIASDILPMDALPDVTFLQGDFREEAVFEKLLNILNGRQVDIVISDMAPNTSGNRAVDQPRQIYLCELALDFAQKVLGPNGQFVVKVFQGAGFDEFRKQVVDSFDVLKTAKPAASRARSKEVFLVGQGRKKALQ
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSA_CUCSA
Sequence: MSIEVRNLSKRFGQFRALNDVSLHIETGELVALLGPSGCGKTTLLRIIAGLESADNGSVLFAGEDATSVDVRQRQVGFVFQHYALFKHMTVFENVAFGLRVKHRSQRPSEDQIQRKVHDLLGLVQLDWLADRYPAQLSGGQRQRIALARALAVEPRVLLLDEPFGALDAKVRKELRRWLRRLHDELNVASVFVTHDQEEALEVADRVVLMNAGRIEQVGTPREVWEGPATPFVYGFLGDVNQLQGVASRGVWEGAGLSLPAPELAQAENQRATAYVRPHEFLYTPAAQEIIAKNYYRPIDKTVAAKYESKFPKVKLVTIDDKIFGGWRKAQKDHFSDGGTFDQIYQPQKK
What is the function of this protein?
Part of the ABC transporter complex involved in sulfate/thiosulfate import.  Responsible for energy coupling to the transport system (By similarity).
What are the official names of this protein?
Sulfate/thiosulfate import ATP-binding protein cysA, Sulfate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Sulfate/tungstate importer (TC 3.A.1.6) family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y526_MYCPN
Sequence: MENTNAKTQPAINELDKTTVQDTIKNYEQQLQKELNEEQLKAFKKRFKYLKLTKREVIEKESRELLLQAFRDFENCEKIKGNHCPNKGNAHLNIFREPPFWTKSNKKVLGKLIGIKMSCAKSIDKEDIFKLRYSNFIIYKPNWFKYADEFPQINQLPINKFQEESFEEIRNDLSELYENEKNHKENISFFNLQKVNFNHEGAKLLLCDFVERGVKTALLYCEEFVSRFDRAYWKVDDYLDLINEANVIIFVSLGEESFVSKNYILFLTRLFDIINSKRKDVYFFSTEYNEKNGLIQAFQKSIHFKAKWVNSFFEQLNYFFEMKREEIK
What are the official names of this protein?
Uncharacterized protein MG350 homolog.
Protein: RL3_DEIGD
Sequence: MTKGILGTKIGMTQIWKGDRAVPVTVVLAGPCPVVQRKTKLTDGYEAVQLGFAPKSEKRVNRPELGHFKKAGVAPMRFLREFRDFAPEGDTVNVDIFAEGEKIDATGTSKGKGTQGVMKRWNFAGGPASHGSKKWHRRPGSIGQRKTPGRVYKGKRMAGHMGMERVTVQNLEVVEVRADENLILVKGAIPGANGGLVMLRQAAKGGK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NOP9_PICST
Sequence: MAKTKSRGRRVEKSADKLEKKAQSLFEDTKSTGEEGGDDSNEIDASLKSPFFGLVDSNELDYFKQAESTLNVNAFDSDEDREGFIRSVLEEARGKELKLVTNQICSKLMERLILFASDRQLKNIFGQFSGHFVALAHHKYSSHVLETLLVRSAALIEKELIHDDSSQNEEEREEQEEGEVTDPMEGLFIKMVDEFKPHLQGMLEHQYSSHVLRLLILILAGKELPSTTTSNSTLRSKKSKIARKMIEIKDNQDFNKSFQTPSSFKIQLRELCNSVSNNQNSKRMRELAIHKIASPVLQLLIQVEGLVDRDRTFWHLIFLKDSEDKNSQEEAFVEYLLSDSVGSHFLEATIKNDGARIKYIERLYKLYMEDRILKLAKRSTTGVYIIQALLFKLKPVDVEHILDEIIPELSNLISISENQNLDLGQRLIDASISRGNYRRDEIIEQLFLKFAPNYNVQDPQLKTTSEFIENVLQLTGSTLGNTRDDWPTAEERRRSFFLEKLMEYDYKFVICVWYNFLALPVERFIQMCFHGVFSHIVERALVVIPSSEGEPKPVLILRKRVLNLFKDQIVNMSCNSYGSHIVDALWNFSVLLPMYKDRIGTELQGDSHKVKESTYGRLVWKNWSMELFVRKKYDWKSLIKQQEQAYYGVNDENGTTSRVKKPIELKMEKLAEERRLREEAAAKSESGYKRRHEDDNEDDYAKKQKLRGRRR
What is the function of this protein?
RNA-binding nucleolar protein required for pre-rRNA processing.  Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity).
What are the official names of this protein?
Nucleolar protein 9, Pumilio domain-containing protein NOP9.
What is the protein family that this protein belongs to?
Belongs to the NOP9 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: NS1_I30A0
Sequence: MDSNTVSSFQVDCFLWHVRKRFADQKLGDAPFLDRLRRDQKSLRGRASTLGLDIETATRAGKQIVERILEEESNEALKMTIASVPASRYLTDMTLEEMSRDWFMLMPKQKVAGSLCIRMDQAIMEKSIILKANFSVIFDRLETLILLRAFTEEGAIVGEISPLHSLPGHTDEDVKNAVGVLIGGLEWNGNTVRVSENLQRFAWRSRNENERPSLPPKQKREVAGTIRSEV
What is the function of this protein?
Inhibits post-transcriptional processing of cellular pre-mRNA, by binding and inhibiting two cellular proteins that are required for the 3'-end processing of cellular pre-mRNAs: the 30 kDa cleavage and polyadenylation specificity factor/CPSF4 and the poly(A)-binding protein 2/PABPN1.  In turn, unprocessed 3' end pre-mRNAs accumulate in the host nucleus and are no longer exported to the cytoplasm.  Cellular protein synthesis is thereby shut off very early after virus infection.  Viral protein synthesis is not affected by the inhibition of the cellular 3' end processing machinery because the poly(A) tails of viral mRNAs are produced by the viral polymerase through a stuttering mechanism.
What are the official names of this protein?
Non-structural protein 1, NS1, NS1A.
What is the protein family that this protein belongs to?
Belongs to the influenza A viruses NS1 family.
What are the subcellular locations of this protein?
Host nucleus. Host cytoplasm. Note=In uninfected, transfected cells, NS1 is localized in the nucleus. Only in virus infected cells, the nuclear export signal is unveiled, presumably by a viral protein, and a fraction of NS1 is exported in the cytoplasm.
Protein: ARLY_PROMT
Sequence: MEKALSKTWSERFDKGLNPFIEKFNASIEFDICLLEEDLDGSIAHARMLGIQGIITKEEALRLENGLQQIRKEASDGLFHPVISDEDVHFAVEKKLIDLIGPVGKKLHTGRSRNDQVGTDLRLWLRKRIDEIDMDLVRLQKSLFLLAEENLYTLIPGYTHLQRAQPLSLAHHLLAYIEMAQRDRNRLKDVRKRVNISPLGAAALAGTSISISRKITSSELHFQGIYSNSLDAVSDRDFVVEFLGASSLIMAHLSRLSEEVILWASEEFAFIQLTDRCATGSSLMPQKKNPDVPELVRGKSGRVFGHLQAMLTMIKGLPLAYNKDFQEDKEAIFDSVKTVKNSLIAISILFEEGLIFRKERLNQAVSSDFSNATDVADYLVAKDIPFREAYQLVGRIVKTSLEEGILLKDIPLERWKTFHKFFEKDIYEKLLPSSVVESRLSAGGTGFERVQEQLLSWREKLFN
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS27A_PYRNV
Sequence: MSKKAPAQKKLPRAAAWYEIDMQKGVFRFKNKLCPKCGSVMAFHREPVPRWHCGKCGFTQFQR
What are the official names of this protein?
30S ribosomal protein S27ae.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS31 family.
Protein: XNI_SHIB3
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: SSDH_ARATH
Sequence: MVIGAAARVAIGGCRKLISSHTSLLLVSSQCRQMSMDAQSVSEKLRSSGLLRTQGLIGGKWLDSYDNKTIKVNNPATGEIIADVACMGTKETNDAIASSYEAFTSWSRLTAGERSKVLRRWYDLLIAHKEELGQLITLEQGKPLKEAIGEVAYGASFIEYYAEEAKRVYGDIIPPNLSDRRLLVLKQPVGVVGAITPWNFPLAMITRKVGPALASGCTVVVKPSELTPLTALAAAELALQAGVPPGALNVVMGNAPEIGDALLTSPQVRKITFTGSTAVGKKLMAAAAPTVKKVSLELGGNAPSIVFDDADLDVAVKGTLAAKFRNSGQTCVCANRVLVQDGIYDKFAEAFSEAVQKLEVGDGFRDGTTQGPLINDAAVQKVETFVQDAVSKGAKIIIGGKRHSLGMTFYEPTVIRDVSDNMIMSKEEIFGPVAPLIRFKTEEDAIRIANDTIAGLAAYIFTNSVQRSWRVFEALEYGLVGVNEGLISTEVAPFGGVKQSGLGREGSKYGMDEYLEIKYVCLGDMNRH
What is the function of this protein?
Oxidizes specifically succinate semialdehyde.  Involved in plant response to environmental stress by preventing the accumulation of reactive oxygen species, probably by regulating proline, gamma-hydroxybutyrate (GHB) and gamma-aminobutyrate (GABA) levels (PubMed:15642352).  Required for the maintenance of the shoot apical meristem (SAM) structure and subsequent adaxial-abaxial axis-dependent development of cotyledons and leaves (PubMed:21690177, PubMed:25840087).
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase, mitochondrial, At-SSADH1, Aldehyde dehydrogenase family 5 member F1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Protein ENLARGED FIL EXPRESSING DOMAIN 1.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: MED31_HUMAN
Sequence: MAAAVAMETDDAGNRLRFQLELEFVQCLANPNYLNFLAQRGYFKDKAFVNYLKYLLYWKDPEYAKYLKYPQCLHMLELLQYEHFRKELVNAQCAKFIDEQQILHWQHYSRKRMRLQQALAEQQQQNNTSGK
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 31, Mediator complex subunit 31, Mediator complex subunit SOH1, hSOH1.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 31 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSE1_ASPCL
Sequence: MFRAQQNAFDDAVAKATDENLTSENWEYILDVCDKVAAEESGAKDAVAAMIKRLAHRNANVQLYTLELANALAQNCGPKIHRELASRSFTDALLRLANDRNTHQQVKSKILERMHDWTRMFSSNPDFGIMEQAYMKLKTQNPNLQPPSKPVKKEITQADRQKEEEELQMALALSIREKSDAGPAPQAESSAPASAPVSQTQAAAPQAVPSGTSAATVSRVRALFDFQPSEPGELQFRKGDIIAVLESVYKDWWKGSLRGQTGIFPLNYVEKLPDPTVEELQREAQMEADVFGQIKNVEKLLTLLSTRSSELNVQDNEEITALYHSTLAIRPKLIELIGKYSQKKDEFTQLNEKFIKARRDYESLLEASMSHPPQPQYARPGQPPYGYPAPTGPHGYPQGAPQPDPQRYFSPRPQDQTHMYPPTSQSPDPRGRTPPAGPTMQQQQQQPPAESFQPMHHRPESTYDNPQELGTSVYDSPVEYPPANQRFQYPPGASAPPGVHQQLQQQQQEYSPSNYSPEDTTNPPTANFPPQPQQSQLPYPTGPAGHQAPPSHQPPPVPGGASKPSPYPSLTPGAPSAGEYQAYNPSQASASSNPASFYR
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein hse1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL11_GLUOX
Sequence: MAKKVVGYIKLQIPAGKANPSPPVGPALGQRGLNIMQFCKEFNAKTQQLEPGMPIPVVITAYADRTFSFITKTPPNTYFLLKAAKISKGSQTVGKSAAVGSVTTAQLREIAETKFKDMNANDIDGAVRMLAGSAKSMGLNVVEG
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NEC2_HHV7J
Sequence: MLKEKMYDELILSTCRVLKLGPADFRVTDKNLFSKNPKFPLCDILLKLDFAYSLEYLLSLWEDLTKQEARFIFKNTGGAVSMSCYLHAPIKQESQNIVKECNILNVNECLSVCLNDIEAIKPSSSGVLTKCIIRRNRDAAFIVEFVAFGPESESEYIALLKAIILKKKFLERQDLEKHRAARHIKKPLRLQLKSVGEMTSFRSINYMGNTKDAAVFPVTVPIFARRNNILCGFLVAALLIVCYVIFKEFALSADFSAV
What is the function of this protein?
Plays an essential role in virion nuclear egress, the first step of virion release from infected cell.  Within the host nucleus, NEC1 interacts with the newly formed capsid through the vertexes and directs it to the inner nuclear membrane by associating with NEC2.  Induces the budding of the capsid at the inner nuclear membrane as well as its envelopment into the perinuclear space.  There, the NEC1/NEC2 complex promotes the fusion of the enveloped capsid with the outer nuclear membrane and the subsequent release of the viral capsid into the cytoplasm where it will reach the secondary budding sites in the host Golgi or trans-Golgi network.
What are the official names of this protein?
Nuclear egress protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae NEC2 protein family.
What are the subcellular locations of this protein?
Host nucleus inner membrane; Single-pass membrane protein. Note=Localizes also at the transient membrane of perinuclear virions.
Protein: SRP72_DICDI
Sequence: MSKDTTVSLEQLFKELDEYIINSQFKKAIRVCNKILSVNGNDSEAFQCKVICLMQLSNFTEAIECFKKPEQIQSMQFEYSYCLYSTAKYQEALTQLEKQSSKETKSLELEAQIYYKLENYQKTISIYESLLSKPGYSDSIEFITNLCAVYLDAGKFNECQELLNKNKSQQTKTHELAFNSACLAISKNDTKTAETQLKLAKKICTDSLKKDGFSEEEIKEEQTSIDVQLGYVQQICGNLEKSLEQYQNVLEQQVGDSATLVATNNSISVRSILQSDQWSTQPKEYTHAMDSLKSLLTEAESTRLNSKQKKVINYNLCLLLVQLKKVSQCEELIKTLKSKYGQQQQQVDTSFVEDLDIIQVSLLIKEKKFKDAEKLLLKNNTTTGSIKSQLLLAQIYLLDNNNVAKALNVLEKLDSSVSLRPGIVATKVALYEKSGDLEKAVNSLDDLISIFDKQKKSEKDEEIYVNLLKASGNFKLKHHKYREASDMFDRVLKINPNDLIALPSYIVATSHFDPSLSQKYEGKLPNIKFESKIDIDLIEKYGLTFEKKLNLNEDSNSSSPTTTTTTTTKSTKPTATEVVKIKKSKKKLPKVMKPNYVPDPGRWLPKWQRANAKAARSKKNKDIIKGPQGIASASQTASLFVQESKNTNTNNNNTQSSKSEKPRNIHKKKSKK
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  Binds the 7SL RNA in presence of srp68 (By similarity).  This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participates in the elongation arrest function (By similarity).
What are the official names of this protein?
Signal recognition particle subunit SRP72, Signal recognition particle 72 kDa protein homolog.
What is the protein family that this protein belongs to?
Belongs to the SRP72 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum.
Protein: CSPA_STRP8
Sequence: MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQTNGFKTLEEGQKVAFDVEEGQRGPQAVNITKLA
What are the official names of this protein?
Major cold shock protein.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YHCI_BACSU
Sequence: MLNLIYNEWLKIFSRAGTWVMIGILGLTMVGFAFLANHFSAGESNSHWKQELQAQNAELKKEIKEDPSLKDGYKETITLNDYRIEHNIPSDTGYTVWSYVTDSANFTILTGLFTIIIAAGIVANEFNWGTIKLLMIRPLSRFQILMSKYITVLLFGLLLLLILFIGSTLLGLIFFGTGGETAANIHLIYKDGHVIEQNMMGHLATTYLSESVSALMVATMAFMLSAVFRNSSLAVGFSIFLLVAGTTATAFIAAKFDWAKYILFANVDLTQYVDGTPLIKGMTMTFSLVMLAIYFIIFLLLAFGIFMKRDIAN
What are the official names of this protein?
Uncharacterized protein YhcI.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RUVB1_DANRE
Sequence: MKIEEVKSTTKTQRIASHSHVKGLGLDEAGNAKQSASGLVGQESAREACGIITELIRSKKMAGRAILLAGPPGTGKTALALAMAQELGNKVPFCPMVGSEVYSSEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIYESLQKERVEVGDVIYIEANSGAVKRQGRCDTFATEFDLEAEEYVPLPKGDVHEKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGVAELVPGVLFIDEVHMLDIECFTYLHRALESSIAPIVVFASNRGNCLIRGTEDISSPHGIPLDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGLNISEEALSHLGEIGTKTTLRYAVQLLTPASLLARVQGREVVEKEHVEEINELFYDAKSSAKILQDQHTKFMK
What is the function of this protein?
Has single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity suggesting a role in nuclear processes such as recombination and transcription (By similarity).  Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding (By similarity).  May act as a negative regulator of embryonic heart growth (PubMed:12464178).
What are the official names of this protein?
RuvB-like 1, Pontin, zPontin.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus. Dynein axonemal particle.
Protein: SN25B_DANRE
Sequence: MADESDMRNELNDMQARADQLGDESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNLTDLGNLCGLCPCPCNKLKGGGQSWGNNQDGVVSSQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVGSIIGNLRHMALDMGNEIDTQNRQIDRIMDMADSNKTRIDEANQRATKMLGSG
What is the function of this protein?
May play an important role in the synaptic function of specific neuronal systems.  Associates with proteins involved in vesicle docking and membrane fusion.
What are the official names of this protein?
Synaptosomal-associated protein 25-B, SNAP-B, Synaptosome-associated protein 25.2, SNAP-25.2.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Synapse, synaptosome. Cell membrane. Note=Complexed with macromolecular elements of the nerve terminal.