PharMolix/UniProtQA huggingface dataset:
Protein: CRTC2_BOVIN
Sequence: MATSGANGPGSATASASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGCGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYARHIDSSPYSPAYLSPPPESSWRRTMPWGSFPAEKGQLFRLPSALNRTSSDSALHTSVMNPSPQDTYPSPAAPSVLPSRRGGCLDGETDSKVPAIEENLLDDKHLLKPWDAKKLSSSSSRPRSCEVPGINIFPSPDQPATVPVLPPAMNTGGSLPDLTNLHFPPPLPTPLDPEETAYPSLSGGSSTSNLTHTMTHLGISGGLALGPGYDAPGLHSPLSHPSFQSSLSNPNLQASLSSPQPQLQGSHSHPSLPASSLARHALPTTSLGHPSLSAPALSSSSSSSSASSPVLGAPAYPASAPGASPRHRRVPLSPLSLPAGPADARRSQQQLPKQFSPTMSPTLSSITQGVALDTSKLPTDQRLPPYPYSPPSLVLPTQQPTPKPLQQPGLPSQACSVQPSGGQPPGRQLQYGTLYPPGPSGHGQQSYHRSMSDFSLGNLEQFNMENPSTSLALDPPGFSEGPGFLGGEGPVSGPQDPHALNHQNVTHCSRHGSGPNVILTGDASPGFSKEIAAALAGVPGFEVSAAGLGLGLGLEEELRMEPLGLEGLSMLSDPCALLPDPAVEDSFRSDRLQ
What is the function of this protein?
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites.  Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation.  Enhances the interaction of CREB1 with TAF4.  Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway.  Regulates the expression of specific genes such as the steroidogenic gene, StAR.  Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells (By similarity).
What are the official names of this protein?
CREB-regulated transcription coactivator 2, Transducer of regulated cAMP response element-binding protein 2, TORC-2, Transducer of CREB protein 2.
What is the protein family that this protein belongs to?
Belongs to the TORC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocated from the nucleus to the cytoplasm on interaction of the phosphorylated form with 14-3-3 protein. In response to cAMP levels and glucagon, relocated to the nucleus.
Protein: FHBP_NEIMB
Sequence: MNRTAFCCLSLTTALILTACSSGGGGVAADIGAGLADALTAPLDHKDKGLQSLTLDQSVRKNEKLKLAAQGAEKTYGNGDSLNTGKLKNDKVSRFDFIRQIEVDGQLITLESGEFQVYKQSHSALTAFQTEQIQDSEHSGKMVAKRQFRIGDIAGEHTSFDKLPEGGRATYRGTAFGSDDAGGKLTYTIDFAAKQGNGKIEHLKSPELNVDLAAADIKPDGKRHAVISGSVLYNQAEKGSYSLGIFGGKAQEVAGSAEVKTVNGIRHIGLAAKQ
What is the function of this protein?
A bacterial surface lipoprotein that binds host (human) complement factor H (fH, gene CFH), binding contributes to the avoidance of complement-mediated lysis by N. meningitidis.  Binding of fH to the bacteria surface is independent of bacterial sialic acid moieties (PubMed:16751403).  fH binding affinity is high enough that it may sequester plasma fH, depleting its circulating levels and de-regulating complement in the host (Probable).  This protein induces high levels of bactericidal antibodies in mice (PubMed:12642606, PubMed:15039331, PubMed:15664958, PubMed:21753121, PubMed:23133374).
What are the official names of this protein?
Factor H binding protein, fHbp, Genome-derived Neisseria antigen 1870, GNA1870, Lipoprotein 2086, LP2086.
What is the protein family that this protein belongs to?
Belongs to the factor H binding-protein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Secreted. Extracellular vesicle, bacterial extracellular vesicle. Note=Surface exposed on encapsulated and non-encapsulated strains. In freshly innoculated cells no secreted protein is seen, as cultures grow the amount of protein in the cell supernatant increases.
Protein: RS6_SHIBS
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: GHRB_KLEP7
Sequence: MKPSVILYKTLPDDLLQRLEEHFSVTQVKNLRPETVSQHAEAFAQAEGLLGSSEKVDAALLEKMPKLRATSTVSVGYDNFDVEALNARRVLLMHTPTVLTETVADTVMALVLSTARRVVEVAERVKAGEWTKSIGPDWFGTDVHHKTLGIVGMGRIGMALAQRAHFGFGMPILYNARRQHPQAEERFNARYCDLDTLLQEADFVCLILPLSEETHHLFGQAQFAKMKSSAIFINAGRGPVVDEQALIAALQNGEIHAAGLDVFEHEPLAKDSPLLSLPNVVALPHIGSATHETRYNMAACAVDNLIDALNGNVEKNCVNPQVK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase B.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_PHOV8
Sequence: MTDPIADYLTRLRNAISAKHRVVEVPASNLKKEITKILFDKGYILNYKFVEDGPQGTIKVALKYDSVNKVNAIKKLIRVSTPGLRKYTGYKDMPRVINGLGIAIISTSKGVMTNKEAAELKIGGEVLCYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ILVD_HAEI8
Sequence: MPKLRSATSTQGRNMAGARALWRATGMKENDFGKPIIAVVNSFTQFVPGHVHLKDMGQLVAAEIEKAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPTIFVSGGPMEAGKTKLSDQLIRLDLVDAMIEAADPNVSDERIDAIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADRKELFLKAGRQIVELCKRYYEQDDASVLPRSIGTFDAFENAMSLDIAMGGSSNTVLHLLAAAQEAGVDFKMEDIDRLSRKVPCLSKIAPNTNKYHMEDVHRAGGIMGLLGELDRAGLIHKNTHTVLGMSMGEQLDQYDIIRNQDEELHKFFRAGPAGIRTTQAFSQDCRWDTVDNDRVNGCIRNKENAISQEGGLAVLFGNLAEDGCIVKTAGVDESIWKFTGTAIVFESQEDAVAGILGGKVKEGHVVVIRYEGPKGGPGMQEMLYPTSYLKSMGLGKKCALLTDGRFSGGTSGLSIGHASPEAASGGAIGLVRDGDIINIDIPNRAINLEISNDELAARRAEQDQKGWQPANREREVSFALKVFGHFATSADKGAVRDKTLLK
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PGLY_STRCO
Sequence: MAQPPLLRDVIDIKESISTSDFVLSLAEATTPAGAQHALRDYVVTERLLENFDEALALIKSSLDGHRSKAAYLHGSFGSGKSHFMAVLYALLSGDQAARARTEFDPVLTKHQWLSTDGKKFLLVPYHMLGAKALEQRVLGGYVTHVKKLCPEAPTPQVYRTDSLFADIRAMRANMGDEAVIRALGTSGADDAEEDEWGEGFAWTPQLLDTALAAEESHEAGVHLNLTNPSTPAELRAKLVNDAGTNLLPGFTQNAAEDEHGFISLDAGLSVIAEHAKSLGYDGLILFMDELILWLATLIHDQKFVAREASKITNFVEGGDARRAIPVMSFIARQRDLRELVGEEVSGAAESSIQDTLNLASGRFDKITLEDRKLPQIAHARLLKPKDAEAAQQVDAAFEQTKRVGPQVWDTLLGSEKGTTGADAESFRLTYPFSPAFMDTLVHISSALQRSRTGLKLMGQLLADHRDELRLGQLVPVGDLYPVIAQGGDKPFTDSLKVVFEAADKLYKTKLRPYLLSSYDITEDDVEQYRNRPESLTDPKKLNGCRMFTGDNRLVCTLLLSALAPSVPALSELTIRRLGALNHGSVLAPIPGAEVGIIKNKVAEWAARFPEIKETGTDANPGVRLELSGVDVDSVIANAQVNDNPGNRVALARRLLSEELGVEHGQLSDQLGFTWRGTARTAEIVFGNVADEDELPDHDLMPQEEGRWRIAIDLPFDEGEWGPVEDVNRVQRLRERQQGERSRTIAWLPAHLSATRFADFRRLVVIDKALADEHRFDTQYAGHLNADNRSRAKGLLETQREALLKQAKGAFKQAYGLAQKQAADVVPDFDDHLVALPDVDGLTLSFGQSLHDGIRHVAGKLLTHQYPAHPDLDPDATGTAVKPADTKKVFAHVRAAAEARDGRIEVPAADRKLMQRIAGPLRLGQQKEAYFELSRYWGDHFRQLARSQGVTGDLSLITLTDWTDRPDPRGLPDFLARLVVAAFAEMDDRVWVRGGTVLDPAPELAAIKDHDALRSQPLPAESDWDTARQRFETVFGAKPPALRRGRMVNQFARQIIEAARDYRDHAADLVHQLEAHASFLGLDQTADTGRLALARRSLQLLDALTAEAGKGAAGAKKTVEALASFDLGETSADRYGTSIKKARAVAEAVASAPWSTLELAAGLGPEGEALLDSLRNVARDDQRTADLRDALARTQREVVALIKRTQAAATPPPAPAASQPTAGDLSLDTPTSDPRIPYTSQETPTSSGGAGTARTSGGRRTTAARAVTDLQAELSDLAVRHPEATIEITWRVVE
What is the function of this protein?
Hydrolyzes ATP but not AMP, ADP, GMP, GDP or GTP; activity is inhibited by the non-hydrolyzable ATP analog 5-adenylyl beta,gamma-imidodiphosphate.
What are the official names of this protein?
ATPase PglY, Bacteriophage (PhiC31) resistance gene PglY, ORF1.
Protein: GDE1_ASHGO
Sequence: MKFGKTFPNHQVPEWAHKYVNYKGLKKQIKEITLVQDALFRQEQGAASQDGPARRRGRESKEQYLGHPEVKKLLAAFFFALDRDIEKVDGFYNMQFMEYDRRLRKLLSSAQLADITSVQRGATGYLHAPLPQYIAYGERERDGLPERYVPPHATDMSEDLAEVLTILLELRSHFRNLKWYGELNKRAFTKIMKKLDKKVGTNQQHSYFQARIKPLEFADDTPIVKALATINEILDRISPCVKDLQDKLRGEDRRLLQGSSSPIDVASQLVTKDDGAGLINELISMYRSVVLIPTRTLVTLLNKSALSRSFSCVDEILGIIPTLGDPSDINGRNFFHHHVIALGKKRTKSLEERDNINSLLSDSLDLEAAIPPEPNTRLVGAFGPDGVNSDDSPAPLSHILQQLPAHLRPSLLQRDNYKRTPLHYSAQYGLCEVTRIILQALSEWDAWNADVAIDDIDVWGDSENLTPLHLAVIGTHPLTVSTLLSFMNPEKSLNSPRLLHLATRLNSPSLLNSLLSAKGFDIDYQEPENLETALYVACKLDIYEAAEYLVKQGANMELGEKLFGWTPIFAAATEGYARIVQLLVDHGAKYDLFDESGWTPMEHAALRGHLDISQLIRITDNKAITRPKFATDWNKSTRPTETTNGLLSALTPSESGSTTTGSENKSSSLTPSTSNEMYALPARSSTSIDKISEPNKGNHRKVLKSQLSHGKVQTIKDTQLPQQPIKSFGHSFLQKDESVILLTLGTNDNRSTIPAVSLNKVPVAKASSTELDTALSLLVTCMDNLDAEPVMLDLPLHENLDSVTFKVPYKKDSSYTIFFDIVPTYGYSMANMNRENSSGMHSNVGNSTGPAYLDAQVGQCGSRLHYDQLGRDTPNTYDQRSRHQASQQKEQIATKKQSKILGRAVALLDSAPTSVGPNRRSIAEAITIPIIGSDTLEVLGIIRFDFLVVTPFVHKNLSVGPAETYWKSLVSTRVIGHRGLGKNMNTNKSLQLGENTVESFIAAASLGASYVEFDVQLTKDNIPVVYHDFLVAESGVDIPMHELTLEQFLDLNGERQRHQDAREAHRNHRSPNGRRLSMDDSSAELIKRSLMMRGDEDRTARDLNTIYGDRMRLTRTFKKNAFKANSRGHAIASSFVTLKELFKKIPQNVGFNIECKYPMVDEAEEEDIGPIAVEMNHWIDTVLEVVYDNVEGRDVIFSSFQPDVCLMLSLKQPSFPILFLTEGGTAKRCDIRAASLQNAIRFAHRWNLLGIVSAAAPIVIAPRLAQIVKSSGLVCVTYGVENNDPEIARVEMDAGVDAVIVDSVLAVRKGLTREAQDADTL
What is the function of this protein?
Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and choline.  The choline is used for phosphatidyl-choline synthesis.  Required for utilization of glycerophosphocholine as phosphate source.
What are the official names of this protein?
Glycerophosphocholine phosphodiesterase GDE1, Glycerophosphodiester phosphodiesterase GDE1.
What is the protein family that this protein belongs to?
Belongs to the GDE1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_MANSM
Sequence: MFDIGFSELLLIFIVGLVVLGPKRLPVAIRTVMGWVRTIRGLAANVQNELAQELKLQELQESIKKAENLNLKNLSPDLAKTVEELKASAEKMKADLDKAAAETNTTIDEQIQILREENAQTQSNDVATSDTVEKSIADEFSIKNDENPTALSSVVSSVDSIQNGQSDLELDAQAEVDRQLAAMMDKYAPPDDVAENPISTEKTS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: Y1250_THEVO
Sequence: MPKISLIGKDLAKEGIEFVFAGPLPTCSDCRVKNVCFNLEQGHKYRVTKVREQLNPCIIFNGDKVNTVEVEELEDFFIIQESKKLQEGAIVTMKSMNCDYITCPNIEKCNLYYQKNDLKVAIKSIGQNVNCPKGFKMKKVQVTYK
What are the official names of this protein?
UPF0179 protein TV1250.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: EX7S_STRSV
Sequence: MSKEKKFEENLADLEVIVQKLENGDVALEEAIAEFQKGMKLSKELQASLDKAEKTLVKVMQADGTETEME
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLNB1_METIV
Sequence: MKMIRAILRPDKVEEVVDALSNAGHVALTKMDVIGRGKQKGIRLDNIYYDELPKVMLLLVTPSEEIDDIIEIINETAFTGNFGDGKIFISPVEEAYTVRTRSKGL
What is the function of this protein?
Could be involved in the regulation of nitrogen fixation.
What are the official names of this protein?
Nitrogen fixation nifHD region GlnB-like protein 1, ORF-105.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.
Protein: NU4M_CANLU
Sequence: MLKIIIPTIMLIPLTWMSKPNMIWINTTTYGLLISLISLFYLNQPNDNTLNSSLMFFSDSLSAPLLALTTWLLPLMLMASQHHLSKEPLTRKKLYISMLILLQLFLIMTFTASELIFFYILFEATLIPTLIIITRWGNQTERLNAGLYFLFYTLMGSLPLLVALLYIHNFMGSLNFLMIQYWIQPLPNSWSNIFLWLACMMAFMVKMPLYGLHLWLPKAHVEAPIAGSMVLAAVLLKLGGYGMMRITTLLNPLTNFMAYPFMMLSLWGMIMTSSICLRQTDLKSLIAYSSVSHMALVIVAVLIQTPWSYMGATALMIAHGLTSSMLFCLANSNYERIHSRTMILARGLQTLLPLMAAWWLLASLTNLALPPTINLIGELFVVMSSFSWSNITIILMGINITITALYSLYMLITTQRGKYSHHIKNIKPSFTRENALMTLHLLPLLLLSLNPKIILGPIY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RABEK_RAT
Sequence: MKQLPILEPGDKPRKAAWYTLTCPGDKPCPRVGHSCSYFPPVGEAEKGKVFIVGGANPNQSFSDVHTMDLGTHRWDTATREGLLPRYEHASFLPSCSPHSIWVFGGADQSGNRNCLQVMNPEARTWSTPEVTGCPPSPRTFHTSSAAIGNHLYVFGGGERGAQPVQDVKLHVFDANTLTWAQPETHGSPPSPRHGHAMVAAGTKLFIHGGLAGDRFFDDLHCIDIGDMSWQKLGPTGTAPVGCAAHAAVAVGHHVYVFGGMTATGALNTMYKYHTEKQHWTILQFDTSLPPGRLDHSMCVIPWPVMSASDTEDSGSVILSLQDEKGDAAEKPETRSGGSREESPTTLLLCFVFGGMNTEGEIYDDCLVTVVD
What is the function of this protein?
Rab9 effector required for endosome to trans-Golgi network (TGN) transport.
What are the official names of this protein?
Rab9 effector protein with kelch motifs.
What are the subcellular locations of this protein?
Cytoplasm. Endosome membrane. Note=Interaction with PIKFYVE and subsequent phosphorylation recruits it to the endosomal membrane.
Protein: COV1_ARATH
Sequence: MGDEKPVIVMANRERDRELLIPVADSGDKDDGSSSKPSSSSSASSSSHQSSHETLSLFIRGWASKKFMTGCVILLPIAITFYITWWFIHFVDGFFSPIYAQLGINVFGFGFLTSIAFIFLVGVFMSSWLGASVLNLGEWFIKRMPFVRHIYNASKQISTAISPDQNTQAFKEVAIIRHPRVGEYAFGFITSTVVLQNYPTEEELCCVYVPTNHLYIGDILLVNSNDVIRPNLSVREGIEIVVSGGMSMPQILSTVDKPLASIDRATSL
What is the function of this protein?
Involved in the regulation of vascular patterning in the stem, probably by negatively regulating the differentiation of vascular tissue.
What are the official names of this protein?
Protein CONTINUOUS VASCULAR RING 1.
What is the protein family that this protein belongs to?
Belongs to the plant COV1 protein family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SULA_SALPA
Sequence: MYTSGYANRSSSFPTTTHNAARTATENAAAGLVSEVVYHEDQPMMAQLLLLPLLRQLGQQSRWQLWLTPQQKLSREWVQSSGLPLTKVMQISQLAPRHTLESMIRALRTGNYSVVIGWMTEELTEEEHASLVEAAKVGNAVGFIMRPVRAHALPRRQHSGLKIHSNLYH
What is the function of this protein?
Component of the SOS system and an inhibitor of cell division.  Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments.  In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring.  This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
What are the official names of this protein?
Cell division inhibitor SulA.
What is the protein family that this protein belongs to?
Belongs to the SulA family.
Protein: PGS2_CANLF
Sequence: MKATIIFLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEDRAPDMPDLELLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHTLILVNNKISKISPGAFTPLLKLERLYLSKNHLKELPEKMPKTLQELRAHENEITKVRKAVFNGLNQMIVVELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITTIPQGLPPSLTELHLEGNKITKVDASSLKGLNNLAKLGLSFNSISAVDNGTLANTPHLRELHLDNNKLIRVPGGLAEHKYIQVVYLHNNNISAVGSNDFCPPGYNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK
What is the function of this protein?
May affect the rate of fibrils formation.
What are the official names of this protein?
Decorin, Bone proteoglycan II, PG-S2.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ATPF2_RUEST
Sequence: MATTTHDAGHGAAEAAHGSSGMPQLDFSTYGNQIFWLLVTLVVIYLILSRIALPRIAAILNERQGTITNDLAAAEDLKAKAVEAENAYNKALADARAEAQRIAAETRAEIQAEVDEAIAKADAEISAKAAESEKAIAEIRAGALESVKVVAADTASALVAALGGKDDADAVKAAVAERTEG
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).  The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria (By similarity).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS8E_THEKO
Sequence: MAIWQGRSLKKPSGGRIILARKKRKRELGREPANTKVGEDREKRKIIRTYGGNRKVRLVEALYANVFEGGKGKKVKILNVVENPANRQYARRNIITKGAIIETEIGKAIVTSRPGQDGVVNAVLIKEENA
What are the official names of this protein?
30S ribosomal protein S8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family.
Protein: RX21_DROME
Sequence: MGDQRGTRVYVGNLTDKVKKDDLEGEFTKYGKLNSVWIAFNPPGFAFVEFEHRDDAEKACDILNGSELLGSQLRVEISKGRPRQGRRGGPMDRGGRRGDFGRHSITSGGSGGGGFRQRGSSGSSSRHTERGYSSGRSGASSYNGREGGGSGFNRREVYGGGRDSSRYSSGSSASYGRTGGQSAGRFRSRSPVGNHRF
What is the function of this protein?
May control important aspects of development.
What are the official names of this protein?
RNA-binding protein Rsf1, RNA-binding protein Rox21.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ASAP1_HUMAN
Sequence: MRSSASRLSSFSSRDSLWNRMPDQISVSEFIAETTEDYNSPTTSSFTTRLHNCRNTVTLLEEALDQDRTALQKVKKSVKAIYNSGQDHVQNEENYAQVLDKFGSNFLSRDNPDLGTAFVKFSTLTKELSTLLKNLLQGLSHNVIFTLDSLLKGDLKGVKGDLKKPFDKAWKDYETKFTKIEKEKREHAKQHGMIRTEITGAEIAEEMEKERRLFQLQMCEYLIKVNEIKTKKGVDLLQNLIKYYHAQCNFFQDGLKTADKLKQYIEKLAADLYNIKQTQDEEKKQLTALRDLIKSSLQLDQKEDSQSRQGGYSMHQLQGNKEYGSEKKGYLLKKSDGIRKVWQRRKCSVKNGILTISHATSNRQPAKLNLLTCQVKPNAEDKKSFDLISHNRTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQSAGENSLEDLTKAIIEDVQRLPGNDICCDCGSSEPTWLSTNLGILTCIECSGIHREMGVHISRIQSLELDKLGTSELLLAKNVGNNSFNDIMEANLPSPSPKPTPSSDMTVRKEYITAKYVDHRFSRKTCSTSSAKLNELLEAIKSRDLLALIQVYAEGVELMEPLLEPGQELGETALHLAVRTADQTSLHLVDFLVQNCGNLDKQTALGNTVLHYCSMYSKPECLKLLLRSKPTVDIVNQAGETALDIAKRLKATQCEDLLSQAKSGKFNPHVHVEYEWNLRQEEIDESDDDLDDKPSPIKKERSPRPQSFCHSSSISPQDKLALPGFSTPRDKQRLSYGAFTNQIFVSTSTDSPTSPTTEAPPLPPRNAGKGPTGPPSTLPLSTQTSSGSSTLSKKRPPPPPPGHKRTLSDPPSPLPHGPPNKGAVPWGNDGGPSSSSKTTNKFEGLSQQSSTSSAKTALGPRVLPKLPQKVALRKTDHLSLDKATIPPEIFQKSSQLAELPQKPPPGDLPPKPTELAPKPQIGDLPPKPGELPPKPQLGDLPPKPQLSDLPPKPQMKDLPPKPQLGDLLAKSQTGDVSPKAQQPSEVTLKSHPLDLSPNVQSRDAIQKQASEDSNDLTPTLPETPVPLPRKINTGKNKVRRVKTIYDCQADNDDELTFIEGEVIIVTGEEDQEWWIGHIEGQPERKGVFPVSFVHILSD
What is the function of this protein?
Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6.  May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2.  May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity).  Plays a role in ciliogenesis.
What are the official names of this protein?
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, DEF-1, Differentiation-enhancing factor 1, PIP2-dependent ARF1 GAP.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Note=Predominantly cytoplasmic. Partially membrane-associated.
Protein: RPOA_ROSDO
Sequence: MIHKNWAELIKPQQLDVKPGNDPARQATVTAEPLERGFGLTMGNALRRVLMSSLQGAAITSVQIDNVLHEFSSVAGVREDVTDIILNLKGVSIRMEVEGPKRLSISAKGPGVVTAGDISESAGIEILNRDHVICHLDDGADVYMELTVNQGKGYVSAEKNKPEDAPIGLIPIDAIYSPVKKVSYDVQPTREGQVLDYDKLTMKVETDGSLTPDDAVAFAARILQDQLGIFVNFEEPESASRADEDDGLEFNPLLLKKVDDLELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLSGMGLHLGMDVEDWPPDNIEDLAKKFEDSF
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: HDA_ECOSM
Sequence: MNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILKL
What is the function of this protein?
Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN).  Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity).
What are the official names of this protein?
DnaA regulatory inactivator Hda.
What is the protein family that this protein belongs to?
Belongs to the DnaA family. HdA subfamily.
Protein: NUOD_RICAH
Sequence: MTNNTKTITLNLGPQHPATHGVLRLILEMDGEIVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEHAFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRPGGVAEDLPDGLLEDIDKFIDQFPPKLHDIESLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYDVYDEMEFEVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTNDPKLTPPTRAKMKESMEAMIHHFKLYTAGYDVPAGETYKAVEAPKGEFGVYLYSQGVNIPYRCRIKSPGFAHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: G3P1_DROME
Sequence: MSKIGINGFGRIGRLVLRAAIDKGASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYVVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYSPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPAATGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGATYDEIKAKVEEASKGPLKGILGYTDEEVVSTDFFSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKD
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase 1, Glyceraldehyde-3-phosphate dehydrogenase I, GAPDH I.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.