PharMolix/UniProtQA huggingface dataset:
Protein: UFD2_YEAST
Sequence: MTAIEDILQITTDPSDTRGYSLLKSEEVPQGSTLGVDFIDTLLLYQLTENEKLDKPFEYLNDCFRRNQQQKRITKNKPNAESLHSTFQEIDRLVIGYGVVALQIENFCMNGAFINYITGIVSNVNSYTDFLSQIIQRAILEGTALDLLNAVFPTLLEYCNKHVSHFDLNESVIYNNVLTIFELFVTFKPIAEIFTKIDGFFADYSCKPQDFERKTILGPILSLSPIEAAVAIRNYGDNLLRSKQQTAMIHESLQAEHKVVIDRLFFIVDKLVRGSLNSRTDMISYFAHIANKNHLRRADHPPFKELSSNGFMSNITLLLVRFSQPFLDISYKKIDKIDANYFNNPSLFIDLSGETRLNSDFKEADAFYDKNRKTADSKPNFISDCFFLTLTYLHYGLGGTLSFEEKMGSEIKALKEEIEKVKKIAANHDVFARFITAQLSKMEKALKTTESLRFALQGFFAHRSLQLEVFDFICGASTFLIRVVDPEHEFPFKQIKLPLIPDQIGVENVDNADFLRAHAPVPFKYYPEFVVEGPVNYSLYISKYQTSPIFRNPRLGSFVEFTTMVLRCPELVSNPHLKGKLVQLLSVGAMPLTDNSPGFMMDIFEHDELVNKNLLYALLDFYVIVEKTGSSSQFYDKFNSRYSISIILEELYYKIPSYKNQLIWQSQNNADFFVRFVARMLNDLTFLLDEGLSNLAEVHNIQNELDNRARGAPPTREEEDKELQTRLASASRQAKSSCGLADKSMKLFEIYSKDIPAAFVTPEIVYRLASMLNYNLESLVGPKCGELKVKDPQSYSFNPKDLLKALTTVYINLSEQSEFISAVAKDERSFNRNLFVRAVDILGRKTGLASPEFIEKLLNFANKAEEQRKADEEEDLEYGDVPDEFLDPLMYTIMKDPVILPASKMNIDRSTIKAHLLSDSTDPFNRMPLKLEDVTPNEELRQKILCFKKQKKEEAKHKASE
What is the function of this protein?
E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly.  Binds to CDC48 and elongates mono- and diubiquitinated ERAD substrates presented by the UFD1-NPL4-CDC48/p97 (UNC) AAA ATPase complex to a chain length of 4 to 6 ubiquitin moieties.  Delivers these polyubiquitinated substrates to RAD23 and DSK2, which target them to the proteasome.  Has E3 ubiquitin-protein ligase activity, accepting ubiquitin from its cognate E2 ubiquitin-conjugating enzyme UBC4.  Enhances ubiquitination at 'Lys-48', but not at 'Lys-29' of the Ub moiety.  Promotes ubiquitin chain elongation at 'Lys-48' on the DOA10 substrate PEX29.  Also involved in the proteolytic processing of the ER-bound transcription factor SPT23.
What are the official names of this protein?
E4 ubiquitin-protein ligase UFD2, RING-type E3 ubiquitin transferase UFD2, Ubiquitin conjugation factor E4, Ubiquitin fusion degradation protein 2, UB fusion protein 2.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin conjugation factor E4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RIR2B_PONAB
Sequence: MGDPERPEAAGLDQDERSSSDTNENEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
What is the function of this protein?
Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner.  Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2.  Contains an iron-tyrosyl free radical center required for catalysis.  Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage (By similarity).
What are the official names of this protein?
Ribonucleoside-diphosphate reductase subunit M2 B.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus in response to DNA damage.
Protein: MTMRB_HUMAN
Sequence: MWWGGRGQSFNIAPQKEEPEMGSVQENRMPEPRSRQPSSCLASRCLPGEQILAWAPGVRKGLEPELSGTLICTNFRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSLHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHSDVVLVDTMDELPSLADVQLAHLRLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGYDPEHCPDSWLPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAISSESLADQEWGLPSHWGACPLPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPTISGLQDELSHLQELLRKWTPRISPEDHSKKRDPHTILNPTEIAGILKGRAEGDLG
What are the official names of this protein?
Myotubularin-related protein 11, Cisplatin resistance-associated protein, hCRA, Inactive phosphatidylinositol 3-phosphatase 11.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
Protein: RECO_LEGPA
Sequence: MTSKSLNAWVIHKQWSGDTSARLKLFTRELGLINCLCKGGRTPKKQSLLQAFIPLWVSIEERYDQYYTRNIESTSSRLDLEGHSLFSGLYINELLYYTLSPDFPDSDLFDAYLFTLNGIALAREREAIEALLRRFEWALLKACGYTFSFLHEARTGELIVPDSHYQFVAGEGFILGGDKKIPGEHLLAIAADNLSESAYLKSAKFIMRQAIDHLLGGREIKARSLYGPA
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: FLIE_SALNS
Sequence: MAAIQGIEGVISQLQATAMAASGQETHSQSTVSFAGQLHAALDRISDRQTAARVQAEKFTLGEPGIALNDVMADMQKASVSMQMGIQVRNKLVAAYQEVMSMQV
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: TXTR3_LASSB
Sequence: MKLSTFIIMISLAVALATWPSEHIEGSDSETKLNVELGPYALADRAEKGKDDSLNKGEPCQFHCECRGASVLCEAVYGTRSPMYKCMIKRLPISVLDIMYQAERALEKLASSFRCE
What are the official names of this protein?
U3-theraphotoxin-Lsp1a, U3-TRTX-Lsp1a, LTx5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. F7 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DXS_CHLPM
Sequence: MADSRSLLDTINSPRDLKKLSIRQLETLANECRHELINLISLNGGHFASSLGVTELSVALHHVYNTEKDRIVWDVGHQAYIHKMLTGRRERMNSNRKYGGISGFPKIHESPHDAFGTGHASTSISAAAGIASARDLKGGNEKVIAVIGDGSMTGGMAFEAMNHLGDLKNDVLVILNDNQMAISPSTGGLKTHMVNFTLNKTYNKARRLLWESMSMMNNDLAERAKTSLRRLEDGMKAALTPGAFFEALGLRYFGPIDGHNMGQLVRALREMQELPHPKLLHVITTKGKGFLPAEENQSDWHAHNGGFDTVTGITAKKEGPSATPKYQEVFGEALVEMALKDPAITAITAAMPTGTSLDLFQKAMPDRFYDVGIAEGHAVTFAAGQALEGLKPVCAIYSTFLQRALDQVIHDVALQNLPVVFAIDRAGLVGEDGPTHHGAFDLSYLHAVPGLTIMAPSDGQELRDMLHTALYHIDGPVAIRYPRGSTGGEEMRKNFTALEPGKGRMLKEGTGPVILTLGTMAATALEAGRLLENEGISVEIADMRFLKPLDTALIDRLSASATHIVTLEENSIIGGFGSAVADHLSEASKKTRLLRIGLPDAFVTHGSMTDLYRETGLDAPAVAEKIRLFYTGRES
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: NEP_I78A3
Sequence: MDSNTVSSFQDILMRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQSRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: SULH1_SCHPO
Sequence: MSFIKKIKHYFADPADLPQDEAPDSVPGLVPPPSNFVPVYPEPTYSDTVSKKGTIVRVVRHTASKLTKHGDSSQSLSTLPNNDISVGEYVEPLPSVPGWLKQNIFSHFGTRLLHYLRSLFPIMNWLPRYNWNWLVYDFIAGITVGCVVVPQGMSYAKVATLPAQYGLYSSFVGVAIYCIFATSKDVSIGPVAVMSLVTSKVIANVQAKDPNYDAAQIGTTLALLAGAITCGLGLLRLGFIIEFIPVPAVAGFTTGSALNIMAGQVSSLMGYKSRVHTNAATYRVIIQTLQNLPHTKVDAAFGLVSLFILYLVRYTCQHLIKRYTKFQRVFFLTNVLRSAVIIIVGTAISYGVCKHRRENPPISILGTVPSGFRDMGVPVISRKLCADLASELPVSVIVLLLEHISIAKSFGRVNDYKVIPDQELIAMGATNLIGVFFHAYPATGSFSRSAINAKSGVRTPLGGIFTAGVVVLALYCLTGAFYYIPNAVLSAVIIHSVFDLIIPWRQTLLFWRMQPLEALIFICAVFVSVFSSIENGIYTAVCLSAALLLFRIAKPSGSFLGILKIANKFDDDENSIDVVRDIYVPLNQKGMNPNLTVRDPPAGVLIFRLQESFTYPNAGHVNSMLTSKAKTVTRRGNANIYKKASDRPWNDPAPRKKKNAPEVEDTRPLLRAIILDFSAVNHIDTTGVQALVDTRKELEIYAGDEVEFHFTDINNDWIKRTLVAAGFGKARDATKYTSRSIEVGSAAPLRDIETPMAPGNSRIVMPSSVRVRPFDEEEAIESSIPAIVSEDGADSDTISVSDDKDKKVEGHRPSQDPTFSHHEYYPVISTTYPFFHVDVTSAVVDIQYRHVLDVNYKPKIVTNEVENENIEHSDGAA
What is the function of this protein?
High affinity uptake of sulfate into the cell.
What are the official names of this protein?
Probable sulfate permease C3H7.02.
What is the protein family that this protein belongs to?
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS19_SULAC
Sequence: MSPEIPPEWKKFRYRGKSLEDLLNMPMDEFIKLLPSRQRRSLKRGFSDKQRRLLEKIRKISREGKQNKVIKTHVRNMVILPEMVGLRFAVYNGKEFVEFQVVPEMIGRYLGEYSITTKKVEHGEPGLKATKSSLFLAMKG
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: MCCA_SOYBN
Sequence: MASLALLRRTTLSHSHVRARAFSEGKSSNRHRIEKILVANRGEIACRITRTARRLGIQTVAVYSDADRDSLHVATADEAIRIGPPPARLSYLNGASIVDAAIRSGAQAIHPGYGFLSESADFAKLCEESGLTFIGPPASAIRDMGDKSASKRIMGAAGVPLVPGYHGYDQDIEKMKLEADRIGYPVLIKPTHGGGGKGMRIVHTPDEFVESFLAAQREAAASFGVNTILLEKYITRPRHIEVQIFGDKHGNVLHLYERDCSVQRRHQKIIEEAPAPNISADFRAQLGVAAVSAAKAVNYYNAGTVEFIVDTVSDEFYFMEMNTRLQVEHPVTEMIVGQDLVEWQILVANGEALPLSQSQVPLSGHAFEARIYAENVQKGFLPATGVLHHYHVPVSSAVRVETGVKEGDKVSMHYDPMIAKLVVWGENRAAALVKLKDSLSKFQVAGLPTNVNFLQKLANHRAFAIGNVETHFIDNYKEDLFVDANNSVSVKEAYEAARLNASLVAACLIEKEHFILARNPPGGSSLLPIWYSSPPFRIHHQAKRRMELEWDNEYGSGSSKIMKLTITYQPDGRYLIETEQNGSPVLEVKSTYVKDNYFRVEAAGVINDVNVAVYSKDQIRHIHIWQGSCHHYFREKLGLELSEDEESQHKPKVETSANPQGTVVAPMAGLVVKVLVENKTRVEEGQPVLVLEAMKMEHVVKAPSSGYVHGLQLMVGEQVSDGSVLFSVKDQ
What is the function of this protein?
Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism.
What are the official names of this protein?
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial, MCCase subunit alpha, 3-methylcrotonyl-CoA carboxylase 1, 3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MEF2A_XENLA
Sequence: MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSSNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCESPDDQRYFEEETFSKLIEDSDFVFKRDPALNKKENRGCDSPDPDGSYVLTPHTEEKYKKINEEFDNMMRSHKISPGLPQQTFPMSVTVPVSNPNTLPYSSPGNTMVTASLAASASLTDARMLSPPPTTLHRNVVSPGLPQRPPSTGNAGVMLCSSDLSVPNGAGTSPVGNGFVNPRASPSHLGPTGGNVLGKVMPTKSPPPPGGNLVMNSRKPDLRVVIPPSSKGMMPPLNTQRVTSSQGTQPLATPIVSVATPSLAPQGLIYSAMPTAYNTDYPLTSADLSMLQGFNSPGILPLGQVSAWQQHHVGQAALSSFVATGQLSQGSNLSINTNQNINIKSEPISPPRDRITPSGFQSHQHHQHQPRPEMDSLSSSSSSYDGSDREDVRNDFHSPIGLGRPANNEDRDSPSVKRMRMDAWVT
What is the function of this protein?
May regulate muscle-specific transcription in the embryo and may regulate transcription of a variety of cell types in the adult.  Binds to the sequence 5'-CTA[TA]4TAR-3'.  Acts downstream of nlk2 in anterior neural development, including eye formation.
What are the official names of this protein?
Myocyte-specific enhancer factor 2A homolog, XMEF2A1, xMEF2A, Serum response factor-like protein 2, SL-2.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACPS_POLSJ
Sequence: MIYGVGTDICDVRRIRASLERHGERLAQKILSEAELATWKERSERWPDRGVRYLATRFSAKEAFSKAIGLGMRMPMTWRHCEISKAASGKPEIVLHGPLKDWFETRQLSVHVSVTDENEYAASFCVVEKNDF
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF172_DANRE
Sequence: MQLKYMKTLLTPQDGAAKVTCMAWAPNNAKFAVCTIDRVVILYDEQGEKRDRFTTKPADPKYGKKTYVVKSMAFSPDSTKIAVAQTDNIIFVYKIGEEWGDKKVICNKFIQTSAVTSLVWPSEHAIIFGLAEGKVRQANTKTSKSSTIYGTDSYVVSLTSNVSGKGILSGHADGTVVRYFIDDEGSGESQGKLLTHACPPYALAWGTNSIIVAGCDKKIVAYGKEGNVIQTFDYSRDRAEKEFTVAASSPSGQSIVVGSFDRLRVFNWSPRKGTWDESSPKEIPNLYTITALSWKKDGSRLSVGTLCGGVEMFDCCLRRSIYKNKFEMTYVGLSQVIVRNLSTGTRVVLKSQYGYEIDEVKVMGKDQYLVAHTSDTLLLGDLVSNKLSEVAWQGSGGNEKFFFENETVCMIFNAGELALVEYGSNDILGSVRTEFMNPHLISVRLNERRQRGVEDNKKLAYLIDIKTIAIVDLVGGYNLGTISHDSKIDWLELNETGRKLLFRDKKLRLHLYDIESSVKSTMLSFCPYVQWVPGSDVVVAQNRGNLCVWYTIDSPERVTMFPLKGDIVDLERSNGKTEVIVNEGVNSISYTLDEGLIEFGTAIDDGDYYRATAFLETLEMSAETEAMWKTLSKLSLEAQQLHIAERCFAALGDVSKARFLNETNKIADAVAKEYDGDGTDHYQVKARLAMLDKNFKLAEMYYMEQNAVDEVMEMYQELHMWDECIAVAEGKGHPELDNLRRSYYSYLMETNQNEKAAEVKENEGDFTGAVNLYLKAGLPAKAAWLAMSKDELLSSQDIVSRITAALIKGEFYERAGDLFERTRNNQRALECYRKGNAFKKAVDLARVAFPAEVVKLEEVWGDYLVQQKQMDAAINHYIEAGRSIKAIEAAIAARQWKKALHILELQEDRTAAKYYLKIAQYYASVQEFEVAERLFVKGDHIKDAIDMYTQAGRWEQAHKLAVKCMTQEDVSVLYVSRAQELEKEGKYKEAERLFTTVDEPDLAITMYKKNKMYDDMIRLVAVHHKDLLQETHIHLAKELEAESRFQEAEYHYLEGQDWKAAVNMYRVNDMWEEAYRIAKTHGGANAHKQVAYLWAKSLGGEAAVKLLNKFGLLETAIDFAADNYTFDFAFELARLSMKQKIPDIHLKNAMFLEDQGKFNEAEIEFIKAGKPKEAVLMHVHNKDWSNAQRVAEAHDPESVADILVSQAKFCFDQKEFQKAEAFLLRAQRPELAIKYYKDAGMWTDAMRICKDYLPSKLSVLQKEYESEGNWGVEGMIEQAQEWEQTGEYSRAVDCYLKVKDSSNLDLLLKCWMKAAELAIKFLSHDKAVDVSQIVGPRLIQLRKYNEAAELYLNLDLIKNAIDAFIEGEEWNKAKRVAKELDPRLEEYVDKRYKEHLKNQGKVDSLVGVDVVAALDMYAERGQWEKCIDTASKQNFKVLHKYIALYATHLIKEGEVEKVLSLYIQHGVPAYSQNFNIYKRMFQELVNLRDRDCAEAFRMWSDLRDVLLLLCENLTKSSEANSPAHEEFEQMLLVAHYYATRSAAKGIDQLSSVAAKLSISLLRHTELIPADKAFYEAGLAAKAVGWENMAFIFLNRFLDLADGIDEGTLDALDHTDFQDTDIPFEVPVPSRLHVTVEKREEIREWVLTVSMDQRVEQVLPKDERGTYEASLVAASTGIRSLPCVITGYPVLRNKIEFKRPGMAANKDDWNKFLMATKTTHSPECQDVLKFITQWCGGLPSAGYSFH
What is the function of this protein?
Required for the maintenance and formation of cilia.
What are the official names of this protein?
Intraflagellar transport protein 172 homolog.
What is the protein family that this protein belongs to?
Belongs to the IFT172 family.
What are the subcellular locations of this protein?
Cell projection, cilium.
Protein: FPG_XANAC
Sequence: MPELPEVETTLRGLSPHLVGQRIHGVILRRPDLRWPIPEQIERLLPGATITNVRRRAKYLLIDTDAGGSVLLHLGMSGSLRVLPGDTLPRAHDHVDISLQSGRLLRFNDPRRFGCLLWQSGTQAHDLLAALGPEPLSDAFTGDYLHALAQGRRAAVKTFLMDQAVVVGVGNIYAAESLHRAGISPLREAGKVSLERYRRLADAVKDILAYAIQRGGTTLRDFISPDGAPGYFEQELFVYGREGEACKQCGRVLKHATIGQRATVWCGSCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PSBD2_SYNP6
Sequence: MTIAVGRAPAERGWFDVLDDWLKRDRYVFVGWSGLLLFPCAYLALGGWLTGTSFVTSWYTHGIASSYLEGGNFLTVAVSTPADAFGHSLMLLWGPEAQGNFVRWCQLGGLWNFVALHGAFGLIGFMLRQFEIARLVGVRPYNAIAFSGPIAVFVSVFLMYPLGQSSWFFAPSFGVAAIFRFLLFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFEDSEQSNTFRAFEPTQAEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSSIGIVGLALNLRAYDFVSQELRAAEDPEFETFYTKNILLNEGIRAWMAPQDQPHEKFVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein 2, PSII D2 protein 2, Photosystem Q(A) protein 2.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MIAA_HISS2
Sequence: MNKKSTAIFLMGPTASGKTDLAIQLHQELPVEVISVDSALIYKGMDIGTAKPNAQELALTPHRLIDIKDPSENYSAAEFRRDALREMQKITQQGKIPLLVGGTMLYYKALLEGLSPLPSADEKVRLEIEQKAEKFGWATLHNELAKIDPISAQRINPNDSQRINRALEVFYLTGQSLTELTAQKGEEIPYHIIHFAIAPERAVLHQRIEQRFHKMIEQGFQQEVEKLYQRSDLHPNLPSIRCVGYRQMWEYLQGNYGKDEMIFRGICATRQLAKRQLTWLRGWKSPIEWLDSLNPKSAKEKIIKTIKHNCK
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: TIKI1_AMPQE
Sequence: MQVKIVQVFPCLVLLVKLVLLSVLLPSATGSYHCSNNATQNSYLWRIEASPPIYLFGTMHVPYKKLWDDVPDNVKSVLSLSEHLCVELRLTDSETSKNLSACRYLPKNETLESVLPGGLYVRVLKYFVRIQNQFPKWLFGNASINGLSRIESDRLFHAMIGNWNRLRPVWLLMLISSLSRENVQERSIPLLDVFLDRAAEGMGKNVEAVEVYKEQCRPFNRLNNTKVFVALRKLLDYLEPLADGPISSTDSDLETYNCGDFKSLVSARPILPLPSSSKLPNLTSEEAGDLESINEFLVSQIVYRRNRRMSKTIMSLLSRQRNETYLFAIGAGHFVGERNVVHMLKKKGYSVNRLSVTETIPGPPLPKNIISLGDPSSQLTILNISSTIPTLPPNRPSHVPPTLSPETIARIIQSVFNNTQSIYTVDSVEVTPTTTSLNSATASTTVATPTSSVTPPTSSSSQTRSLTISDSQRTSDDSAFIPSASSGLRYNIGLVCVTLFFVLLIITSAL
What is the function of this protein?
Metalloprotease.
What are the official names of this protein?
Metalloprotease TIKI homolog.
What is the protein family that this protein belongs to?
Belongs to the TIKI family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: CAPSD_BPGA1
Sequence: MSRISIQDFKESLGITESYDIINAIINENPRFSEFSTLANAQDVANFGIGLLADKTLQNDFIHTLVDRIGLVVVHHKLMQNPLKIFKKGTLEYGRKIEEIFTDLTREHVYDPEKAETEVFKREIPNVKTLFHERDRQVFYKQTISDQQLKTAFTNAQKFDEFLSTIVTSIYNSAEVDEFRYTKLLIDNYFSKNLFKIVPVSVDPATGIVNTKEFLAKTRATATKMTLPMGTRDFNSMAVHTRTDMDDLYIIMDADTQAEVDVNELASAFNLNKADFIGRRILIDGFASTGLKAVMVDKDFFMLYDQVFRMESQRNAQGMYWNYYLHVWQVLSTSRFANAVAFVDSALIDGDVSQVIVTPTVGSLKSGKSLDMEAIIRTITPNVQIEDVEWSLENVGLSSAEYATVSITANENKTGAKLVSAQPLPVGGDVRVKVTVTDPKNNKDIEGEAHISIIPDFNATPIQTPVDPPSGE
What is the function of this protein?
Assembles to form a prolate capsid of about 45x54 nm, with a T=3, Q=5 symmetry.
What are the official names of this protein?
Major capsid protein, Gene product 8, gp8, Major head protein.
What is the protein family that this protein belongs to?
Belongs to the phi29 phage major capsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Forms the capsid shell which contains about 218 major capsid proteins.
Protein: EGR2_POERE
Sequence: AEGCDRGFSRSDELTRHIRIHTGHKPFQCRICMRNFSRSDHLTTHIRTHTGEKPFACDYCGR
What is the function of this protein?
Sequence-specific DNA-binding transcription factor.  Binds to two specific DNA sites located in the promoter region of HOXA4.
What are the official names of this protein?
Early growth response protein 2, EGR-2, Zinc finger protein Krox-20.
What is the protein family that this protein belongs to?
Belongs to the EGR C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZYS3_CHLRE
Sequence: MLRSAGRVAAVALLALFALGCVSAAAKPSTDRLVAAIKSKNLSAVVDALSVKGLDVNTPDSTRRLPLVEAARSRDARLVGALLDQGALARVSDGTTTPLHLSMQGGSAAIVKLLLAHGADPNAKDKTGASARSTAAAVKELADLLKQWDARGAMAFEDEPGAWIREERDGQSYYWKPANGESRWAVPPSCAWQRVTVQGHPIKYINSLTGQETTRVPPALAWARVTAADGSALWLNWASRVASAAATAPAELPAELAAELAMHPNRRWYNTATREYVYTDPAYATPWRELVDEASGAPFFFNVETGDTTWELPAALAWTEVIESSSGADGESGSGSEAGPRYFHNTVSGEVAWSAPEGSRHVFVEASAADL
What is the function of this protein?
May have a role in the remodeling of the endoplasmic reticulum upon zygote formation.
What are the official names of this protein?
Zygote-specific protein 3.
Protein: SIM38_HUMAN
Sequence: MTSWPGGSFGPDPLLALLVVILLARLILWSCLGTYIDYRLAQRRPQKPKQD
What are the official names of this protein?
Small integral membrane protein 38.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL32_KOCRD
Sequence: MAVPKRKMSRANTRMRRSQWKAQAPKLVKTVENGKVSYSLPHQAKLVSDSAGTPLFYEYKGRKVADA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: GLYA_RICB8
Sequence: MNIFNNKLQEIDKGIFEIIKHEKTRQNSVIELIASENFVSPAVLEAQGSVLTNKYAEGYSGKRFYNGCEEVDKAENLAIERAKKLFNCKYANVQPHSGSQANQAVYLALMQPGDTVLGMSLDSGGHLTHGSTANMSGKWFNAVSYSVDKETYLIDYDEVERLAILHKPKLLIAGFSAYPRNLDFAKFREIADKVGAYLMADIAHIAGLVAAGEHQSPIPHAHIVTSTTNKTLRGPRGGLILSNDEEIGKKINSALFPGLQGGPLMHIIAAKAVAFLESLQPEYKSYIKQVIINAKALAGSLQERGYDILTGGTDNHIVLVDLRKDGITGKIAANSLDRAGITCNKNAIPFDKTSPFITSGIRLGTPACTTRGFKEKDFVLVGHLIADILDGLKNSEDNSKAEQKVLSEVTKLIKLFPFYD
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.
What are the official names of this protein?
Probable serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTAR1_HUMAN
Sequence: MAETSEEVAVLVQRVVKDITNAFRRNPHIDEIGLIPCPEARYNRSPIVLVENKLGVESWCVKFLLPYVHNKLLLYRTRKQWLNRDELIDVTCTLLLLNPDFTTAWNVRKELILSGTLNPIKDLHLGKLALTKFPKSPETWIHRRWVLQQLIQETSLPSFVTKGNLGTIPTERAQRLIQEEMEVCGEAAGRYPSNYNAWSHRIWVLQHLAKLDVKILLDELSSTKHWASMHVSDHSGFHYRQFLLKSLISQTVIDSSVMEQNPLRSEPALVPPKDEEAAVSTEEPRINLPHLLEEEVEFSTDLIDSYPGHETLWCHRRHIFYLQHHLNAGSQLSQAMEVDGLNDSSKQGYSQETKRLKRTPVPDSLGLEMEHRFIDQVLSTCRNVEQARFASAYRKWLVTLSQ
What are the official names of this protein?
Protein prenyltransferase alpha subunit repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein prenyltransferase subunit alpha family.
Protein: RL9_CORDI
Sequence: MKLILTADVENLGVAGDIVEVKDGYGRNLLLPRGLAIVATRGAEKQIEGIKRAQEAREIRDLDHAREVKAQLEALEGVSVAVRTSEKGKLFGSVKAEDVAAAVKKAGGPNLDKRSIELPKSLVKATGAYKVNVKLHSDIAATVNFEVVAA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.