PharMolix/UniProtQA huggingface dataset:
Protein: Y2512_DICDI
Sequence: MKLLLILILIINNYNLCLSYECNSNRTYGLKGSSCEINADCLFPEVCFNSVCSKIRTTGESCTKKTDCTLTYDFGDCVNGKCEIIIATGDRCNPKVTSQKCSSSSECKNGICQLISACNSYNCPLNQYCDDKTKQCKPIPNDINSIVCKANSQCPTSHICTSSNKCIIKYSSKVGEKCTDSPLQCRVFNGEICNQETQKCIKNDQYFKQCEDESTCNGGLCVCLDDVNSKSVCVGPNGELNNEKCVNLEQKLEQCLINEKCNTLSPITCKCFKQFECFQYECNSVERFYNYKSNYYQSLNCSRFLTKP
What are the official names of this protein?
Uncharacterized protein DDB_G0272512.
What are the subcellular locations of this protein?
Secreted.
Protein: UPP_XANCP
Sequence: MKIVEVRHPLVQHKIGLLRDAALSTKGFRELVTELGTLLAYEATANLDTESHVQPGWAGPVEVQRIAGAKITLVPILRAGLGMLPGVLALIPAARVSVVGLQRDEETLQPVPYFERLTGRLEERDALILDPMLATGGTLIATIDMLKRAGARRIKGIFLVAAPEGLKALEAVHPDVEVYTAAIDDHLNEKGYILPGLGDAGDRIFGTRVE
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: CDH_SALPK
Sequence: MKKTGYFLLAVIVIVAAAGVGYWKFSGNPDALREIVLEQCLPDQLQHQNPAPCAEVKPRAGYVVFKDRHGPLQYLLMPTYRINGTESPLLLEPATPNFFWLAWQARGYMSKKYGHDIPDSAVSLAINSRLGRSQDHLHIHISCIRPDVREQLDNDLTRISTRWLPLPGDLMGHEYLARRVTESELAQRSPFMMLAEEVPEARDHMGRYALAVVRQSDGSFVLLATERNLLTFNRASAEEIQDHSCAILSSR
What are the official names of this protein?
CDP-diacylglycerol pyrophosphatase, CDP-diacylglycerol phosphatidylhydrolase, CDP-diglyceride hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Cdh family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PAND_STAA9
Sequence: MIRTMMNAKIHRARVTESNLNYVGSITIDSDILEAVDILPNEKVAIVNNNNGARFETYVIAGERGSGKICLNGAASRLVEVGDVVIIMTYAQLNEEEIKNHAPKVAVMNEDNVIIEMIHEKENTIVL
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_XYLFM
Sequence: MKPEIHPIYREVVFHDVTSNFKFLTRSTMSTKETTLWEDGREYPLVKVEISSASHPFYTGKHKLVDTSGRIDKFKKRYAR
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: PQQC_PSEP1
Sequence: MSDALPMSPAEFEQALRAKGAYYHIHHPYHVAMYQGRATREQIQGWVANRFYYQVNIPMKDAAILANCPDREVRREWIQRLLDHDGAPGEDGGIEAWLRLGQAVGLDPDQLRSQELVLPGVRFAVDAYVNFARRASWQEAASSSLTELFAPQIHQSRLDSWPQHYPWIDPAGYEYFRTRLGQARRDVEHGLAITLQHYTTRAGQERMLEILQFKLDILWSMLDAMSMAYELNRPPYHSVTQERMWHKGITL
What is the function of this protein?
Ring cyclization and eight-electron oxidation of 3a-(2-amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9-dicarboxylic-acid to PQQ.
What are the official names of this protein?
Pyrroloquinoline-quinone synthase, Coenzyme PQQ synthesis protein C, Pyrroloquinoline quinone biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the PqqC family.
Protein: GEMI7_MOUSE
Sequence: MQSPLTIPVPVPVLRLPRGPDGFSRGFASDGRRTILRPEVGEGHIQDPPESQEQRARATLRERYLRSLLAMVGHPVSFTLHEGVHVTAQFGATDLDVANFYVSQLQTPIGVQAEALLRCSDIISYSFKL
What is the function of this protein?
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.  Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core).  In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP.  To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate.  Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (By similarity).
What are the official names of this protein?
Gem-associated protein 7, Gemin-7.
What is the protein family that this protein belongs to?
Belongs to the gemin-7 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, gem. Cytoplasm. Note=Found both in the nucleoplasm and in nuclear bodies called gems (Gemini of Cajal bodies) that are often in proximity to Cajal (coiled) bodies. Also found in the cytoplasm (By similarity).
Protein: BIP_HUMAN
Sequence: MKLSLVAAMLLLLSAARAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAEKDEL
What is the function of this protein?
(Microbial infection) Acts as a receptor for CotH proteins expressed by fungi of the order mucorales, the causative agent of mucormycosis, which plays an important role in epithelial cell invasion by the fungi (PubMed:24355926, PubMed:20484814, PubMed:32487760).  Acts as a receptor for R. delemar CotH3 in nasal epithelial cells, which may be an early step in rhinoorbital/cerebral mucormycosis (RCM) disease progression (PubMed:32487760).
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, 78 kDa glucose-regulated protein, GRP-78, Binding-immunoglobulin protein, BiP, Heat shock protein 70 family protein 5, HSP70 family protein 5, Heat shock protein family A member 5, Immunoglobulin heavy chain-binding protein.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen. Melanosome. Cytoplasm. Cell surface. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). Localizes to the cell surface of epithelial cells in response to high levels of free iron (PubMed:20484814, PubMed:24355926, PubMed:27159390).
Protein: OSBL6_HUMAN
Sequence: MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW
What is the function of this protein?
Regulates cellular transport and efflux of cholesterol (PubMed:26941018).  Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal membrane (By similarity).  Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid (By similarity).  Weakly binds 25-hydroxycholesterol (PubMed:17428193).
What are the official names of this protein?
Oxysterol-binding protein-related protein 6, ORP-6, OSBP-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope. Cell membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Note=Co-localizes with OSBPL3 at contact sites between the plasma membrane and the endoplasmic reticulum.
Protein: TCTP_TRYBB
Sequence: MKIFRDILTNAEVVXDNDKPMDVLDEIVYAXQGRYIE
What is the function of this protein?
Binds calcium; exact function not known.
What are the official names of this protein?
Translationally-controlled tumor protein homolog, TCTP, 22 kDa calcium-binding protein.
What is the protein family that this protein belongs to?
Belongs to the TCTP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KGUA_COLP3
Sequence: MIVPGNLFILSAPSGAGKSSLINALLKPDNQASARAMQVSISHTTRDARPGENNGEHYHFVSVEEFKKQISLNAFYEYAEVFGNYYGTSEAAIDAQLSQGIDVFLDIDWQGAQQVRMKKPGVTTIFISPPSKEELESRLRGRGQDSDEVIASRMAQAQAECSHYNEFDYVIVNDDFEQALLDLTTIVNNQRLKCRQQSIAQQSLFSKLLNIEAVEPTE
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_ESCF3
Sequence: MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: DIG1_YEAST
Sequence: MAVSARLRTTAEDTSIAKSTQDPIGDTEISVANAKGSSDSNIKNSPGGNSVGQESELEHVPEEDDSGDKEADHEDSETATAKKRKAQPLKNPKKSLKRGRVPAPLNLSDSNTNTHGGNIKDGNLASSNSAHFPPVANQNVKSAPAQVTQHSKFQPRVQYLGKASSRQSIQVNNSSNSYGKPHMPSAGIMSAMNPYMPMNRYIMSPYYNPYGIPPPHMLNKPIMTPYVSYPYPMGPRTSIPYAMQGGNARPYEENEYSASNYRNKRVNDSYDSPLSGTASTGKTRRSEEGSRNSSVGSSANAGPTQQRADLRPADMIPAEEYHFERDALLSANTKARSASTSTSTSTSTNRDRSSWHEAEPNKDEEEGTDLAIEDGAVPTPTFTTFQRTSQPQQQSPSLLQGEIRLSSHIFAFEFPLSSSNVDKKMFMSICNKVWNESKELTKKSSSHHRTGK
What is the function of this protein?
DIG1 and DIG2 are negative regulators of the filamentation and pheromone induced mating program.  DIG1 and DIG2 inhibit the transcriptional activity of STE12 by direct protein-protein interaction.  DIG1 colocalizes to promoters with STE12 and redistributes with it during induction of filamentation (by butanol) or mating (by pheromone) to program specific genes, but binding of DIG1 to STE12 is reduced by pheromone treatment.
What are the official names of this protein?
Down-regulator of invasive growth 1, Regulator of STE12 protein 1, Regulator of sterile twelve 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y480_MYCCT
Sequence: MKLKNNLLEKTLELSELFKIYKELLTDKQKQYFELYIDEDLSLSEIADEFNISKTAVYDSISKTSKLLFSLEKKLHLKQKEELLISLINKIETNQIDEKQFIKSLKEVIWWKY
What is the function of this protein?
Might take part in the signal recognition particle (SRP) pathway.  This is inferred from the conservation of its genetic proximity to ftsY/ffh.  May be a regulatory protein.
What are the official names of this protein?
UPF0122 protein MCAP_0480.
What is the protein family that this protein belongs to?
Belongs to the UPF0122 family.
Protein: RL30_HAEDU
Sequence: MAKTIKVTQTRSSIARLPKHKATLKGLGLRNIRHTVELIDTPAIRGMINQVSYMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: GUN1_BUTFI
Sequence: MHKSKCIKRVFTFLLALFVFVMAIPATKVSAAGGTDRSATQVVSDMRVGWNIGNSLDSFGQSYNFPYTSLNETYWGNPATTKALIDEVAKAGFNTIRIPVSWGQYTTGSDYQIPDFVMNRVKEVVDYCIVNDMYVILNSHHDINSDYCFYVPNNANKDRSEKYFKSIWTQIAKEFKNYDYHLVFETMNEPRLVGHGEEWWFPRNNPSNDIREAVACINDYNQVALDAIRATGGNNATRCVMVPGYDASIEGCMTDGFKMPNDTASGRLILSVHAYIPYYFALASDTYVTRFDDNLKYDIDSFFNDLNSKFLSRNIPVVVGETSATNRNNTAERVKWADYYWGRAARYSNVAMVLWDNNIYQNNSAGSDGECHMYIDRNSLQWKDPEIISTIMKHVDGTPATINGKEIPSTEQPDPTPVDPDPTPVDPDPTPVDPDPTPVDPDPQPVDPTPVSGALKAEYTINNWGSGYQVLIKVKNDSASRVDGWTLKISKSEVKIDSSWCVNIAEEGGYYVITPMSWNSSLEPSASVDFGIQGSGSIGTSVNISVQ
What are the official names of this protein?
Endoglucanase 1, Cellulase 1, Endo-1,4-beta-glucanase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
Protein: HGD_LEGPH
Sequence: MYLQGFGNYHHSEAVKGALPPNQNSPQHCSLGLYAEQLSGTAFTRPRHNNLRSWLYRILPTVTQGTYYPYEFNIMQPFVDELSPNAMRWSPLYNSSQIKCDFVEGLFHIAGSPLVNTYTYYCNHSMSDKYFANNDGELLFVPYAGEIHLHTEFGKLMLSSGSIAVIPRGVKFKVEVISKEAKGYLCENSGNPLTLPQLGPIGANGLANPRHFQYPVAAFENSGSEHTIICKNQKKLWFTVCNHSPLNVVAWHGNYAPYCYDLSLFNTINTVSFDHPDPSIFTVLTSESEIPGVSNLDFVIFPPRWMVAEHTFRPPYFHRNYMNELMGLVYGEYDAKKEGFIPGGISIHNCMTPHGPDYESYEIAASQDLKPNYINSLAFMFETKDYWQVTEQAYRHPSRQMDYLNCWQGFKIEFSQ
What is the function of this protein?
Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine.  Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
What are the official names of this protein?
Homogentisate 1,2-dioxygenase, HGDO, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase.
What is the protein family that this protein belongs to?
Belongs to the homogentisate dioxygenase family.
Protein: HSP17_ARATH
Sequence: MSLVPSFFGGRRTNVFDPFSLDVWDPFEGFLTPGLTNAPAKDVAAFTNAKVDWRETPEAHVFKADVPGLKKEEVKVEVEDGNILQISGERSSENEEKSDTWHRVERSSGKFMRRFRLPENAKVEEVKASMENGVLSVTVPKVQESKPEVKSVDISG
What are the official names of this protein?
17.4 kDa class I heat shock protein, 17.4 kDa heat shock protein 1, AtHsp17.4A.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_RICCK
Sequence: MNIFNNNLHETDKDIDEIIKHEKIRQSSVIELIASENFISPAVLEAQGSILTNKYAEGYPSKRFYNGCEEVDKAENLAIERAKKLFNCKYANVQPHSGSQANQAVYLALLQPGDTILGMSLDSGGHLTHGAAPNISGKWFNAVSYSLNKETYLIDYNEIERLADLHKPKLLIAGFSAYPRNIDFAKFREIADKVGAYFMADIAHIAGLVATGEHQSPLAFAHIVTSTTHKTLRGPRGGLILSNDEEIGKKINSALFPGLQGGPLMHVIAAKAVAFQEALQPKYKSYIQQVISNAEALARILQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAGITCNKNTIPFDKTSPFITSGIRLGTPACTTRGFKEKDFVLVAHMIADILDGCKNNEDNSKAEQKVLTEVTQLIKLFPFYG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_OENOB
Sequence: MIFQIFSALLIGFLIAFAAIPFLIGYLTSRGEVGVERSGKHGFGVDTSGKNGTPSMGGVTFILSSLFATLIVMFLFRLDSLNIIFFIVSFLSFGLIGLIDDALKVFYHRDEGFRFIPKLIAQIISAALITIILVAVHIPDKLTFPFFRALPLYFLVQFIFYLVWFVGWSNAANFVDGIDGLLAGIALLIFAGYGIIGIKENQNLMVIFDFSVVGSLLAYFIFNRPKAKIFMGDCGSMALGAGMAINAIFLQHPWSLLWFGLILALDTTSVMIQVLVYHFFHVRVFPVAPLQHSFQRAGWSEWKIDSLFWTIQLIITMIGVFVWIK
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFA_CAMJE
Sequence: MQNFIEQIQKCENLNDLEAIRISVLGKKGILTEGFTKLKELEDEAKKEFAAKLNAQKEIFNEAYLAKFKDLENLALEERMKQDALNFNYFDESITTGALHPVMSTMDKIIEYFIALNFSIEKGPLIEDDFHNFEALNLPKSHPARDMQDTFYFDDKRLLRTQTSPVQIRTMLAQKPPIRMIAPGAVFRRDFDITHTPMFHQVEGLVVEEGQKVSFANLKSVLEDFLRYMFGDVKVRFRPSFFPFTEPSAEVDISCVFCKGKGCRVCKHTGWLEVLGCGIVDPNVYNFVGYENVSGYAFGLGVERFAMLLHQIPDLRSLFEGDLRLLEQFR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTH_HAEIG
Sequence: MIPQTLEQLLSQAQSIAGLTFGELADELHIPVPPDLKRDKGWVGMLLERALGATAGSKAEQDFSHLGVELKTLPINAEGYPLETTFVSLAPLVQNSGVKWENSHVRHKLSCVLWMPIEGSRHIPLRERHIGAPILWKPTAEQERQLKQDWEELMDLIVLGKLDQITARIGEVMQLRPKGANSRAVTKGIGKNGEIIDTLPLGFYLRKEFTAQILNAFLDVKPL
What is the function of this protein?
Sequence-specific endonuclease that cleaves unmethylated GATC sequences.  It is involved in DNA mismatch repair.
What are the official names of this protein?
DNA mismatch repair protein MutH, Methyl-directed mismatch repair protein.
What is the protein family that this protein belongs to?
Belongs to the MutH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECA_SPIME
Sequence: MEDNKPVPPQTKPLDQDEILKTVMKEIEKTYGKGAIMKLGDKSNLTIEAVSTGSLLLDEAIGVGGYPKGRIIEIFGP
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDUAD_PONPY
Sequence: MGASKVKQDMPPPGGYGPIDYKRNLPRRGLSGYSMLALGIGTLIYGHWSMMKWNRERRRLQIEDFEARIALLPLLQAETDRRTLQMLRENLEEEAIIMKDVPDWKVGESVFHTTRWVAPLIGELYGLRTTEEALHASHGFMWYA
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.  Involved in the interferon/all-trans-retinoic acid (IFN/RA) induced cell death.  This apoptotic activity is inhibited by interaction with viral IRF1.  Prevents the transactivation of STAT3 target genes.  May play a role in CARD15-mediated innate mucosal responses and serve to regulate intestinal epithelial cell responses to microbes.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, Complex I-B16.6, CI-B16.6, NADH-ubiquinone oxidoreductase B16.6 subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA13 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side. Nucleus. Note=Localizes mainly in the mitochondrion. May be translocated into the nucleus upon IFN/RA treatment.
Protein: MIAA_ALBFT
Sequence: MMNTERPAGPLRPPHPPHPPRYLALAGPTASGKTAAALAIARVHEVEIISVDSALVYRGMDIGTAKPSAAELAAVPHHLIDIRDPLQAYSAAEFVADAQALIAAITARGRLPLLVGGTMLYFKALLEGLDPMPKADPATRALIATEAAEQGWPALHAALAEVDPVSAKRLHPADSQRIARALEVYRLSGQPLSSFQTTKLIATNEGVTGARGQKCLNIPENDRCLISLEPQNRAWLHQRIAERFDAMLAAGFIDEVRALRARGDLQADLPAMRCVGYRQAWQALDGLWPMSELRDKGICATRQLAKRQLTWLRSMPERRVVACDAPDALDQVLALARDFVNAGNKLQGQP
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NDK_ECOLU
Sequence: MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARLY_CAUVC
Sequence: MWGGRFSAKPAELMQAINVSIGFDKRLWAQDLAGSRAHARMLMNQGVIASHDGEEILEGLARVEDELLSGTFPFRDEYEDIHMNIEARLRELIGPTAGRLHTARSRNDQVAVDFRLWVRDACDRTVGQLEALQKALLTQAEAHAESLMPGFTHLQPAQPVTFGHHLMAYVEMFGRDAGRFRDARARMNECPLGAAALAGSPFPIDRQQTASALGFDRPTANSLDSVSSRDFALEALSAASITATHLSRLAEEIVLWTTPMFGFIKLTDAFTTGSSIMPQKKNPDAAELIRAKVGRILGSLTTLTVVMKGLPLAYSKDMQEDKVPTFEAFDALELSLLAMAGMIADLTPNTENMAKAAGAGFSTATDLADWLVRTLNMPFRDAHHVTGSAVKTAEGLGVDLADLSLAQFQAIEPQITKEVYAVLTPAASAASRMSYGGTAPAQVRAQIARWKELLA
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TCPD_BOVIN
Sequence: MPENVAPRTGPPAGAAGAAGGRGKSAYQDRDKPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVELSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPEELSDRETLLNSAATSLNSKVVSQYSSLLSPMSVDAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCELVEGLVLTQKVANSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYVQMDRVLREERAYILNLVKQIKKTGCNVLLIQKSILRDALSDLALHFLNKMKIMVVKDIEREDIEFICKTIGTKPVAHVDQFTADMLGSAELAEEVSLNGSGKLIKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCIRAFADAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGGISNILEEQVVQPLLVSVSALTLATETVRSILKIDDVVNTR
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.  The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance.  As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia.  The TRiC complex plays a role in the folding of actin and tubulin.
What are the official names of this protein?
T-complex protein 1 subunit delta, TCP-1-delta, CCT-delta.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm. Melanosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.