PharMolix/UniProtQA huggingface dataset:
Protein: RL16_SYNP2
Sequence: MLSPKRTKFRKQHRGRMRGMAYRGNNIQFGDYALQAVEPSWITARQIEAARRAMTRYIKRGGKIWIRIFPDKPITMRPAETRMGSGKGNPEFWVAVVKPGRIMFEMNGVAEPIAREAMRLAAQKLPIKTKFITRNEEYI
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: Y2131_COXBR
Sequence: MLFWVLIFFIIAVIAALFGFTGIAAASAGIAKILFFIFLVLFVISLIAMLVRGRRPKL
What are the official names of this protein?
UPF0391 membrane protein COXBURSA331_A2131.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OR5K3_HUMAN
Sequence: MNKENHSLIAEFILTGFTYHPKLKTVLFVVFFAIYLITMVGNIGLVALIYIEQRLHTPMYIFLGNLVLMDSCCSSAITPKMLENFFSEDKRITLYECMAQFYFLCLAETTDCFLLAAMAYDCYVAICNPLQYHTMMSKTLCIQMTAGAYLAGNLHPMIEVEFLLRLTFCGSHQINHFFCDVLPLYRLSCINPYINELVLFILAGSIQIFTIVLVSYFYILFTIFTMKSKEGRGKALSTCASHFLSVSIFCDSLLFMYARPGAVNEGDKDIPVAIFYTLVIPLLNPFIYSLRNKEVINIMKKIMKKRKFCHILKQMSSPLAT
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5K3.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS15_BIFA0
Sequence: MALTAEEKQDIIAKYATHEGDTGSPEVQIALLTKRIADLTEHLKFHKHDHHSRRGLLLMVGDRRRLLDYLKKVDIERYRSLIERLGLRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PTF1A_HUMAN
Sequence: MDAVLLEHFPGGLDAFPSSYFDEDDFFTDQSSRDPLEDGDELLADEQAEVEFLSHQLHEYCYRDGACLLLQPAPPAAPLALAPPSSGGLGEPDDGGGGGYCCETGAPPGGFPYSPGSPPSCLAYPCAGAAVLSPGARLRGLSGAAAAAARRRRRVRSEAELQQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQADLPLRGGGAGGCGGPGGGGRLGGDSPGSQAQKVIICHRGTRSPSPSDPDYGLPPLAGHSLSWTDEKQLKEQNIIRTAKVWTPEDPRKLNSKSSFNNIENEPPFEFVS
What is the function of this protein?
Transcription factor implicated in the cell fate determination in various organs.  Binds to the E-box consensus sequence 5'-CANNTG-3'.  Plays a role in early and late pancreas development and differentiation.  Important for determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates.  May be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase.  Required for the formation of pancreatic acinar and ductal cells.  Plays an important role in cerebellar development.  Directly regulated by FOXN4 and RORC during retinal development, FOXN4-PTF1A pathway plays a central role in directing the differentiation of retinal progenitors towards horizontal and amacrine fates.
What are the official names of this protein?
Pancreas transcription factor 1 subunit alpha, Class A basic helix-loop-helix protein 29, bHLHa29, Pancreas-specific transcription factor 1a, bHLH transcription factor p48, p48 DNA-binding subunit of transcription factor PTF1, PTF1-p48.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=In chronic pancreatitis associated with pancreas cancer preferentially accumulates in the cytoplasm of acinar/ductular complexes. In the cytoplasm loses its ability to form the PTF1 complex (By similarity).
Protein: RL36_PROM9
Sequence: MKVRSSVKKISPDDQIVRRRGKIYVINKKRPRNKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: RL11_METFK
Sequence: MAKKVIGYIKLQIPAGKANPSPPVGPALGQRGLNIMEFCKAFNAATQSMEPGLPIPVVITAFADKSFTFVMKTPPATILIKKAAKIDKGSPRPHTDKVGKITRAQAEEIAKTKAPDLTAADLDAAVRTIAGSARSMGIEVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: NAGB_STAS1
Sequence: MKITNLGTSGYASFYVACELYKQMSQQNHSKLGLATGGTMVDVYRFLVQLLRKNKLDVSEIETFNLDEYVGLDAQHEQSYHSYMNEMLFKQYPYFNPSLLHIPNGDADNLNDETKRYEQLINQKGPVDIQILGIGENGHIGFNEPGTDINSATHIVDLTESTISANSRYFDNEVDVPKQAVSMGLSTILKAHRIILLAFGEKKRAAIEKLAENEVNSDVPATILHAHPNVEIYVDDEAAPRL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: OSCP1_RAT
Sequence: MSVRTLPLLFLNLGGEMLYVLDQRLRAQNIPGDKARKVLNDIISTMFNRKFTEELFKPQELYSKKALRTVYDRLAHASIMRLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLDSIKGFIQDSPTIIHQVDETFRQLTEIYGSLSAGEFQLIRQTLLIFFQDLHIRVSTFLKDKVQNSNGRFVLPVSGPVPWGIEVPGVIRVFNDKGDEVKRMEFRHGGDYVAAHKEGSFELYGDRVLKLGTNMYSASRPVETHMSATSKNSASRAQENIAPNPLAKEELNFLARLIGGMEIKKPSGPEPGFRLNLFTTDEEEEHAALSRPEELSYEVISIQATQDQQRSEELARIMEEFEMTEQPERNTSKGDDLLAMMDRL
What is the function of this protein?
May be involved in drug clearance in the placenta.
What are the official names of this protein?
Protein OSCP1.
What are the subcellular locations of this protein?
Basal cell membrane.
Protein: METE_ECODH
Sequence: MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPVLLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAELHKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDISRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
What is the function of this protein?
Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
What are the official names of this protein?
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase, Cobalamin-independent methionine synthase, Methionine synthase, vitamin-B12 independent isozyme.
What is the protein family that this protein belongs to?
Belongs to the vitamin-B12 independent methionine synthase family.
Protein: O52E2_HUMAN
Sequence: MFLPNDTQFHPSSFLLLGIPGLETLHIWIGFPFCAVYMIALIGNFTILLVIKTDSSLHQPMFYFLAMLATTDVGLSTATIPKMLGIFWINLRGIIFEACLTQMFFIHNFTLMESAVLVAMAYDSYVAICNPLQYSAILTNKVVSVIGLGVFVRALIFVIPSILLILRLPFCGNHVIPHTYCEHMGLAHLSCASIKINIIYGLCAICNLVFDITVIALSYVHILCAVFRLPTHEARLKSLSTCGSHVCVILAFYTPALFSFMTHRFGRNVPRYIHILLANLYVVVPPMLNPVIYGVRTKQIYKCVKKILLQEQGMEKEEYLIHTRF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 52E2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: POTA_HAEI8
Sequence: MENQPQNKPIIELRSIKKSYGSNTIINDFNLAINNGEFVTILGPSGCGKTTVLRLLAGLEELDSGSIILDGEDITNVPAEKRHINTVFQSYALFPHMTIFENVAFGLRMQKVPNEEIKPRVLEALRMVQLEEMADRKPTQLSGGQQQRIAIARAVVNKPKVLLLDESLSALDYKLRKQMQQELKMLQRQLGITFIFVTHDQEEAITMSDRIVLLRKGKIAQDGSPREIYEDPANLFVARFIGEINVFEATVIERKSEQVVLANVEGRICDIYTDMPVEKDQKLQVLLRPEDIVIEELDENEHSKAIIGHIIDRTYKGMTLESTVEFDHNGMRVLVSEFFNEDDPHMDHSIGQRVGITWHEGWEVVLNDEDNQ
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GATZ_ECOSE
Sequence: MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQREQLSYVIGTEVPVPGGEASAIQSVHITHVEDTANTLRTHQKAFIARGLTEALTRVIAIVVQPGVEFDHSNIIHYQPQEAQPLAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQSGELSAIPHQLIMDKIYDVLRAYRYGCAE
What is the function of this protein?
Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit.  Could have a chaperone-like function for the proper and stable folding of GatY.  When expressed alone, GatZ does not show any aldolase activity.  Is involved in the catabolism of galactitol.
What are the official names of this protein?
D-tagatose-1,6-bisphosphate aldolase subunit GatZ.
What is the protein family that this protein belongs to?
Belongs to the GatZ/KbaZ family. GatZ subfamily.
Protein: NHAA2_PSYIN
Sequence: MNLRIVYLRSLNIQGLTKMTDDKNNLLHRGLDNIQPPFSNFIRAQATASVFLLVATITALWWANSDYSSTYQMLKHMQIGFFLGDIELQASLKHIINDGLMVIFFFFIGLEIKREVLAGDLAIAENRRMLILCALGGMICPAVIYSLFNWSLDSQIGWGIPMATDTAFALGALTLVRKHIPISLLAFLVGLAIVDDVGAIVVIALFYTQEISVIFLSISFSLIAFLAIANYAGVLRPIFYILIGIAAWWTMLKSGVHPTFAGVAIALTVPARPMLPPDELLSKVKAKITAMKKNKGHQLDALANREDHEQVLDVRDFAEHGSAPLRRWEDALDLPVSLFVLPLFALVNAGVEVSFSSLIETLQHSVGLGIVIGLVIGKFVGISGACWLGLRYKIGSLPEGINMQHVIGMSLIAGIGFTMSTFIATLGFDSQPEYLQSAKGSILFASLLSAILGLLYLRIIAAKKAPNSASKNGEN
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 2, Sodium/proton antiporter NhaA 2.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: HUTH_DEIRA
Sequence: MILDRDLNLEQFISVVRHGEQVELSAAARERIARARTVIEQIVEGDTPIYGVNTGFGKFENVQIDRSQLAQLQHNLIVSHAIGMGEPLPAEVVRGMLLLRAQSLSLGHSGVRVEVVELLLALLNADALPVVPSQGSVGASGDLAPLAHLALGLIGLGDIEYQGQVRPAADVLAELGLSPVQLQAKEGLALINGTQLMGSLLALALHDAQVLLGTANLAAAMTVEARYGSHRPFQPDVVGLRPHPGALAVAAELREFLAGSEIAPSHLTGDGKVQDAYSLRAVPQVHGATWDALAQAERVLAVEFASVTDNPLIFPETGEVVSGGNFHGQPLAVTIDALKVAVAELGSISERRTEQLLNPALSGLPAFLTPNGGLNSGFMIAQYTSAALVSENKVLSHPASVDSIPTSANQEDHVSMGAHAARQLRQIVANVQTVLSIELLCAAQGLDFQQLRAGRGVQAAYEYVRTFVPTLTEDRYFRPDLLRLRGELVSGELLRVAQAADTQAPAPAKLPDSGDEDRDTTSRH
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUMB_MOUSE
Sequence: MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTREGSFRVTTATEQAEREEIMKQLQDAKKAETDKTVVGPSVAPGNTAPSPSSPTSPTPDGTASSEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPSTMQRKTDFPIKNTVPEVEGEAESISSLCSQITSAFSTPSEDPFSSAPMTKPVTLVAPQSPVLQANGTDSASHVLTAKPANTALAHVAMPVRETNPWAHVPDAANKEIAAIHPGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQVSAAPLQPVLQPPPPAAIAPPAPPFQGHAFLTSQPVPVGVVPPLQPAFVPTQSYPVANGMPYPASNVPVVGITPSQMVANVFGTAGHPQTTHPHQSPSLAKQQTFPQYETSSATTSPFFKPPAQHLNGSAAFNGVDNGGLASGNRHAEVPPGTCPVDPFEAQWAALESKSKQRTNPSPTNPFSSDLQKTFEIEL
What is the function of this protein?
Regulates clathrin-mediated receptor endocytosis (By similarity).  Plays a role in the process of neurogenesis (PubMed:10841580, PubMed:12410312, PubMed:15273690, PubMed:17174898).  Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate (PubMed:15273690, PubMed:12410312).  Not required for the proliferation of neural progenitor cells before the onset of neurogenesis (PubMed:15273690, PubMed:12410312).  Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity (PubMed:17174898).  May also mediate local repair of brain ventricular wall damage (PubMed:17174898).
What are the official names of this protein?
Protein numb homolog, m-Nb, m-Numb.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localizes to perinuclear endosomes in an AAK1-dependent manner.
Protein: ISPF_ENDTX
Sequence: MYIGFGYDAHRLKKGRELILGGVKILTSEGLDGHSDADVLIHALMDALLGAAGLNDIGHFFPDMDPKYKNVSSISLLESVYKELKKQNFSVNNVDITVIVEAPKICPFIADMKENISRVIELKRERIGIKATTNEKMGFVGRGEGIAAVAVASISQEKKR
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: LPXK_SYNC1
Sequence: MTKLALFYRHLAVKGPCSPLEWLIFAFLLPLGWLYGAVMRLRALFYRIGWFDAYCADVPVISVGNLSVGGTGKTPVVDYLIRYCRSLDKRVAVVSRGYAGGKGAALRVVCAGQGPILDVQQAGDEPWLLARRNPAAIVIVAPHRAQGVRHAVENLGAEVVLLDDGFQHLAVSRDFDLVLLDALRPFGNGQVLPAGLLREPVSALRRGDLFVLTRCPEDLAGTADVPGPVVHCRHILEESAVDLDGEVRSLRELAGLRGIAFAGIAEPEGFFRELQSHGLTLTRTLHFSDHAAYDERAAILLKDAAKSGDYFITTEKDAVKLAHMTLPLPCFQVPLRLMFVETGQLEQKLSPIISNQR
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: FOLD_ALTMD
Sequence: MTAHLIDGKLIAKQVRQHVTSYVDSLTQAGKRQPGLAVVLVGSDAASQVYVSNKRKACDEVGFVSRSFDLPSDTTEETLLNLVDQLNEDKEIDGILVQLPLPAGLNAEKVLERIHPHKDVDGFHPYNIGRLAQRIPALRPCTPKGIMTMIESTKRPVKGLDAVIVGASNIVGRPMSLELLLAGCTVTTCHKFTQDLKSHVQRADLLVVAVGKPNFIPGDWVKPGAIVIDVGINRVNDGSLVGDVDFDKAKERAGWITPVPGGVGPMTVASLIENTLEAYVKYHS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HMH2_GIRTI
Sequence: MSGIPGLAGMSSMSPYSAYAALTQHTGVSSGSSPFGSQYCSSVNDFNPYSDPRGSNTWYGMAASANASNDPRMTMSRLMGSAAAAASSSMSAYSGIPTNFHQGMHSAMGMASLGAATYDHQKAAMQFNNMSQRRKRRILFSQAQIYELERRFKQQKYLSAPEREHLANLINLTPTQVKIWFQNHRYKCKRSQKDKEKEQQKEKSYHLKKNIVDDKERSPNKQICNASSSDRSTPEEPVAKAKESGLDFSNHKIDNLNLKMEADLEPKSSLYSIIPPYLTNSYAQQTQSEAQTSPIINNVLGSNLFPERKSTPTMGPLTSYSFGQSMDSISSFYSPDFSLYNCAHPYMAASSSYFMNAASRPWN
What is the function of this protein?
This protein might be involved in determination and/or differentiation of nerve cells in the continuous replacement of neurons in the cephalic region.
What are the official names of this protein?
Homeobox protein DTH-2.
What is the protein family that this protein belongs to?
Belongs to the NK-2 homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GPX2_PONPY
Sequence: MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGSGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI
What is the function of this protein?
Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides.  Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
What are the official names of this protein?
Glutathione peroxidase 2, GPx-2, GSHPx-2, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: Y412_METJA
Sequence: MEKDDEVKKRDRMKVKLKVENLTKIFEFNGNRVKALDNINLEVYENEFLTVMGPSGCGKTTLLRIIAGLDYPTEGKVLLDGKEVKGPGADRGVVFQQYTLMPWRTVLKNVTFGLELKGIPKNERIEIAKKFIKMVGLEGFEDAYPYQLSGGMQQRVAIARTLANDPEIVLMDEPFAALDAQTRNILQNELLKIWQKEKKTVFFVTHSVDEAVYLSDRVVVLTARPGRIKEIVKIDLERPRDRTSIEFLEYRKKILNILKDEVLKSLK
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein MJ0412.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: TM168_MOUSE
Sequence: MCRSLRYCVSHCLYLAMTRLEEVNREVNMHSSVRYLGYLARINLLVAICLGLYVRWEKTANSLILVIFILGLFVLGIASILYYYFSMEAASLSLSNLWFGFLLGLLCFLDNSSFKSDVKEETTKYLLLTSIVLRILCALVERISGYVRHRPTLLTTVEFLELVGFAIASTTMLVEKSLSVILLVMALAMLIIDLRMKSFLAIPNLIIFSVLLFFSSLETPQNPIAFACFFICLVTDPFLDIYFSGLSVTERWKPFLHRGRICRRLSVLFTAMIELTFFILSAFKLRDTHLWYFVIPGFSIFGFFWMICHIIFLLTLWGFHTKLNDCHKVYINHRADNNSLDRIMASKGMRHFCLISEQLVFFSLLATAILGAVSWQPTNGIFLSMFLIVLPLESMAHGLFHELGNCLGGTSVGYAIVIPTNFCSPDGQPTLLPPEHVQELNLRSTGMLNAIQRFFAYHMIETYGCDYSTSGLSFDTLHSKLKAFLELRTVDGPRHDTYVLYYSGHTHGSGEWALAGGDILRLDTLLEWWREKNGSFCSRLIIILDSENSTPWVKEVRKINDQYVAVQGAELAKTVDIEEADPPQLGDFTRDWVEYNCNSTNNICWTEKGRTVRAVYGVSKRWSDYTLHLPTGSDVAKHWMLHFPRVTYPLVHLANWLCGLNLFWVCKACFRCLKRLKMSWFLPTVLDTGQGFKLVKS
What is the function of this protein?
Plays a key role in maintaining the cardiac electrical stability by modulating cell surface expression of SCN5A (PubMed:32175648).  Plays a role i the modulation of anxiety behavior by regulating GABAergic neuronal system in the nucleus accumbens (PubMed:29211814).
What are the official names of this protein?
Transmembrane protein 168.
What is the protein family that this protein belongs to?
Belongs to the TMEM168 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: BT3A1_HUMAN
Sequence: MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
What is the function of this protein?
Plays a role in T-cell activation and in the adaptive immune response.  Regulates the proliferation of activated T-cells.  Regulates the release of cytokines and IFNG by activated T-cells.  Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate.
What are the official names of this protein?
Butyrophilin subfamily 3 member A1.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. BTN/MOG family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: RF1_NEIM0
Sequence: MKPSILEKLQQLGDRLEEVTHLLGQPEATADMDNYRKLTREHAELTPVVEVFQNYRLAQSDLADAEEMLSDPEMKDFAAEEIEAAKAKIGALDTELQKLLLPKDADDDKNIFIEVRAGTGGDEAALFAGDLLRMYSRYAERNRWQVEIVSANESELGGYKEVIARIIGLGAYSRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPEADELEDIELNPVDLRIDTFRASGAGGQHINKTDSAVRITHLPTGMVVECQDGRSQHANKAQAMKVLAARLNDAQKREAQAKEAAERKSLIGSGDRSERIRTYNYPQGRVTDHRINLTLHKLDFVMDGDLAEITDALIAEHQAELLAAMGD
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_OENOB
Sequence: MSRIGNKAITIPTGVEIKQEGDQVTVKGPKGEITRSIASVISMNIEGSEAKFSRPDDSNRNKALHGTTRANVANMIEGVSKGFKKNLELVGVGYRASMQGDKLVLTVGFSHPVEFEAREGLKVAVPDATHISIEGISKQRVGDFAAEIRGVRPPEPYKGKGIRYQGEIVRRKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: CSTR2_ARATH
Sequence: MKNGMAECSVCRSRLVSPSSKAISRAYDNYNYKIRVSSKQRALNVFLVVGDCMLVGLQPVLVYMSKVDGKFNFSPISVNFLTEIAKVIFAMVMLLFQARHQKVGEKPLLSLSTFVQAARNNMLLAVPAGLYAINNYLKFTMQLYFNPATVKMLSNLKVLVIAVLLKMIMKRRFSIIQWEALALLLIGISINQLRSLPEGATTVAVPIATGAYICTFIFVTVPSLASVYNEYALKSQYDTSIYLQNLFLYGYGAIFNFLGILGTVIYKGPGSFDILQGHSRATMFLILNNAAQGILSSFFFKYADTILKKYSSTVATIFTGIASAALFGHILTMNFLLGISIVFISMHQFFSPLSKAKDEQQNGNIELVDAKDGHRAKDSFINMAAGATEEASHRIESDDRVPLLPR
What is the function of this protein?
Sugar transporter involved in the transport of CMP-sialic acid from the cytoplasm into the Golgi.
What are the official names of this protein?
CMP-sialic acid transporter 2, CMP-SA-Tr 2, CMP-Sia-Tr 2.
What is the protein family that this protein belongs to?
Belongs to the nucleotide-sugar transporter family. CMP-Sialate:CMP antiporter (TC 2.A.7.12) subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: ATPA_SYNP1
Sequence: MVSIRPDEISSIIRQQIEQYEQSINVDNVGTVLQVGDGIARVYGLDKVMASELVEFEDGTVGIALNLEEDNVGVVLMGAGLGIEEGSTVRATGKIASVPVGEAVIGRVVDALMRPIDGKGEIHATATRLLESPAPGIVQRKSVCEPLQTGITAIDAMIPIGRGQRELIIGDRQTGKTAVAIDTILNQKGQDVICVYVAIGQKASSVAQVVNVLRERGALDYTIVVAANASDPAALQYLAPYTGASIAEYFMYQGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNDALGGGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINAGISVSRVGSAAQIKAMKQVAGKLKLELAQFDELQAFAQFASDLDKATQNQLARGQRLREILKQPQYSPIPVEYQVATIYAGTNGYLDDIPVEAVAKFVAGLRDYLATSKPQYGEAVRSSQKLDETAEALLKEAIAEYKAGFTA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: Y2095_SHEFN
Sequence: MIYTTTETIPGRDIIEIVGVVTGNVVQSKHIGRDIMAGLKSIVGGEIRGYTEMLSDARDVAINRLVASAAQKGADAIVGIRFTTSAIMDGSSEIMAFGTAVKLGPSR
What are the official names of this protein?
UPF0145 protein Sfri_2095.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.