PharMolix/UniProtQA huggingface dataset:
Protein: NANM_SALEP
Sequence: MGMQMKNFKKMMTLMALCLSVAITTSGYATTLPDIPEPLKNGTGAIDNNGVIYVGLGTAGTSWYKIDLKKQHKDWERIKSFPGGAREQSVSVFLNDELYVFGGVGKKNSESPLQVYSDVYKYSPVKNTWQKVDTISPVGLTGHTGVKLNETMVLITGGVNEHIFDKYFIDIEAADESEKNKVIYNYFNKPAKDYFFNKIVFIYNAKENTWKNAGELPGAGTAGSSSVMENNFLMLINGELKPGLRTDVIYRAMWDNDKLTWLKNSQLPPSPGEQQQEGLAGAFSGYSHGVLLVGGGANFPGAKQNYTNGKFYSHEGINKKWRDEVYGLVNGHWQYMGKMKQPLGYGVSVSYGDEVFLIGGENAKGKPVSSVTSFTMRDGNLLIK
What is the function of this protein?
Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers.  Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer.  In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
What are the official names of this protein?
N-acetylneuraminate epimerase, N-acetylneuraminate mutarotase, Neu5Ac mutarotase, Sialic acid epimerase.
What is the protein family that this protein belongs to?
Belongs to the NanM family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CH60_DELAS
Sequence: MAAKDVVFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQLVKEVASKTNDIAGDGTTTATVLAQAIVREGAKYVAAGLNPMDLKRGIDKAVAALVEELKKQSKATTTSKEIAQVGSISANSDESVGSIIAEAMDKVGKEGVITVEEGKSLANELDVVEGMQFDRGYLSPYFINNPEKQVALLDNPFVLLFDKKISNIRDLLPTLEAVAKAGRPLLIIAEDVEGEALATLVVNTIRGILKVVAVKAPGFGDRRKAMLEDIAILTGGKVIAEEVGLALDKVTLEDLGQAVRIEIGKENTTIIDGAGQAAEIEARVKQIRIQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALLRAKQAVGDLKTGDAEQDAGIKLIMKAIEAPLREIVANAGGEPSVVVNAVLNGSGNYGFNAANDTYGDMLEMGILDPTKVTRTALQNAASVASLLLTTEAMIAESPKAEGGPAMPDMGGMGGMGGMGM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAL_SODGM
Sequence: MNQLEGLKQFTTVVADSGDIESIRHYTPQDATTNPSLILKAASLTAYQPLFEDTLAYARKQGGTRETQIINASDKLAVNIGVEILKSVPGRVSTEVDARLSFDRGMCVAKARKLVALYQEQGIDKSRILIKLASTWEGIKAAEELEKEGINCNLTLLFSFAQARACAEAGVYLISPFVGRIYDWYNQRKPLDPYVADEDPGVVSVRKIYDYCKQHRYQTVIMGASFRKVEQILALAGCDRLTISTTLLEELHKADTRVERKLSPSTEGFHQPAPLSEPEFRWEHNQDAMAVDKLAEGIRQFAVDQQSLEDLLAAKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDM12_CANAL
Sequence: MSFDINWNQLTIDDTINQSIKEFLDQQFKNISLPSFISNLAVTDFNLGEIPPEVTIRHIGDPFEEFYEDENNLGVMNEANNDSKDEHLKNHGDGINKDSGYNSQNLDDEDEDDEDDDEDDEDEEEEDEDDYDDHDLGTINEGISLLNFNENSTTPSANSFAGSAAPPLPPPLNPSRDSFHSILHPYGVNSIIGATGAGSETPTNILNQNYLSSRVLPKISVKQKQPHHDDNDIQLIVEINYKGDMHINLLVNLLVNYPSPNFISLPIKLHITDIVIHSIATIAYLKKSVFLSFLCDVDDTFPDFDSNVQTPTSTTGGNFVDYYSNDATINKERIDIVKKIKIESEIGEVENNILRNVGKVEKFLVEQLRNILRDEIAWPSWICIDMNDDDDEEEEEEESEDNDGGNSDLNDNDGKHGDGRTDETEAGE
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria.  MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.  The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex.  The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex.  Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 12, Mitochondrial inheritance component MDM12.
What is the protein family that this protein belongs to?
Belongs to the MDM12 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria-endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: Y520_YERPN
Sequence: MKRTKNINQETFRKSWRSYRLAPVALAVSAVFMLAGCEKTDETVSLYQNADDCSQANPSQSAECTTAYNTALQEAVKTAPKYATREDCVAEFGESQCTQAPAQAGMVPTSSSETTAAAPQQSGSMWMPLMAGYMMGRMMGGGASQPLFTSKAPNSPANGKFVDASGKNFGAATTGRTMTVPKTALAPKPAVTKTITRGGFGESVAKQSSMQRSAATSSKTTTRSMGG
What are the official names of this protein?
UPF0441 protein YPN_0520.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: HS166_ORYSJ
Sequence: MSLVRSGNVLDPMSVDFWADADPFGAVRSLAERCPVLTNVRVDWKETPTAHVFTADLPGVRKDQAKVEVEDGGVLVISGERAREEDVDGKNDERWHHVERSSGKFQRRFRLPRGARVDQVSASMDNGVLTVTVPKEETKKPQLKAIPISG
What are the official names of this protein?
16.6 kDa heat shock protein, OsHsp16.6.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNA14_CRYNB
Sequence: MSHEHPAEIVHQLQSIDSIQQDLADTAAAVVDAASQSLPPQHAAQDQKSHSTLLDNAEAMESILESAIPAAPGSSSTAAASDAIGDNNFTASGPPPISNTVVAPSAADDETGDVIVVESETPTTTNVVEAVVNPENDGDVPIESTEQSSGQPAEQPTEQPTEQPTEQPAEQPAVETPQAPQSTPAAPAASAVESIPTTLEETHLEQIVQAPAPTVHTEPLTPVVDIKMEEKPMIEHVAWIPPQGIHSDVFLPEGLTEYSPSVSQNGELIRSWRADPSNPTLLLSLFNWAVQKTEVEDARAWYRVLAVDNPTAAQPLLALINLELALSNFAEVEAIFASTLKGSAGITTAADVSIWAAYLHYIRRQNPLTEGSANAADVRSTITEAYEFALRECGFDRESGDIWDEYIKFVASGPATNQWDTQAKNDNLRKIYQRAVCIPLNNIEALWKSYDNFESSLNKLTAKKYLAEKSPAYMTARTALRELRALSDPIPKPILPPYPTFTEQDRQVVGAWKACLRWEEGNPLVIENHELLQSRIGYALRKCLGEMRHFPELWHYAASYYSKLGKQDEAAEILEAGVNACPKSFLLTFAYAELQEERKAFPTCHSLYTTLISKLNPEVDELRQNVAREIDIARGPPIPGSEKAAVAAAVGDSIDADGNDISDIQRLVEEREQRGALVAQRRGKDIEELMVGISVVWIMYMRFARRAEGIKAARGVFGKARKSPHLTWQVFEASALMEYHTNKDAAVAIRIFELGLKQFSEDVDYVIKYLQFLLSINDDNNARALFERSVVRIMGDKARPLWDAWARYEYTYGDLSAVHKLEARMSEVFPEDAPLKRFAQRWSYNGIDQIAIRDLGFNRARMGVAAPPAFAIAPVLPPVHASIPAPIAVPTPVQPPQESYKRPAPEDIPPRRPSSAEFSRSPKRHRAQSPPRRYPERDDRPPPGRYRDSLPPVKAPSSIPPPPLAGPAYATPSSGAYGGDKDRSGLEKPLAWFMAQLPNARSFDGPVFRPDDIMKLFGGLSLPGAGMPPAPPISRGPPPPPMQSRGYYEPERDRRYGGHGSGRY
What is the function of this protein?
Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA 3'-end-processing protein RNA14.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleus and/or cytoplasm.
Protein: MZT1_SCHPO
Sequence: MSESTKETIEVLYEIGTLLGTELDKTTLSLCISLCENNVHPEAIAQIIREIRMAQEQTVDTEPS
What is the function of this protein?
Required for gamma-tubulin complex recruitment to the microtubule organizing center (MTOC).
What are the official names of this protein?
Mitotic-spindle organizing protein 1, Mitotic-spindle organizing protein associated with a ring of gamma-tubulin 1, Transcripts altered in meiosis protein 4.
What is the protein family that this protein belongs to?
Belongs to the MOZART1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localizes to all the MTOCs, including the SPB and interphase and equatorial MTOCs.
Protein: RUXX_METBF
Sequence: MANRPLDILNNALDTPVIVRLKGAREFRGELKGYDIHMNLVLDNAEELREGEVVSKFGSVVIRGDNVVYVSP
What are the official names of this protein?
Putative snRNP Sm-like protein.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family.
Protein: OADB2_SALTI
Sequence: MESLNALLQGMGLMHLGAGQAIMLLVSLLLLWLAIAKKFEPLLLLPIGFGGLLSNIPEAGMALTALESLLAHHDAGQLAVIAAKLNCAPDVHAIKEALALALPSVQNQMENLAVDMGYTPGVLALFYKVAIGSGVAPLVIFMGVGAMTDFGPLLANPRTLLLGAAAQFGIFATVLGALTLNYFGLIAFTLPQAAAIGIIGGADGPTAIYLSGKLAPELLGAIAVAAYSYMALVPLIQPPIMRALTSEKERKIRMVQLRTVSKREKILFPVVLLLLVALLLPDAAPLLGMFCFGNLMRESGVVERLSDTVQNGLINIVTIFLGLSVGAKLVADKFLQPQTLGILLLGVIAFGIGTAAGVLMAKLLNLCSKNKINPLIGSAGVSAVPMAARVSNKVGLESNPQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVLAM
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Oxaloacetate decarboxylase beta chain 2.
What is the protein family that this protein belongs to?
Belongs to the GcdB/MmdB/OadB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ATG3_HUMAN
Sequence: MQNVINTVKGKALEVAEYLTPVLKESKFKETGVITPEEFVAAGDHLVHHCPTWQWATGEELKVKAYLPTGKQFLVTKNVPCYKRCKQMEYSDELEAIIEEDDGDGGWVDTYHNTGITGITEAVKEITLENKDNIRLQDCSALCEEEEDEDEGEAADMEEYEESGLLETDEATLDTRKIVEACKAKTDAGGEDAILQTRTYDLYITYDKYYQTPRLWLFGYDEQRQPLTVEHMYEDISQDHVKKTVTIENHPHLPPPPMCSVHPCRHAEVMKKIIETVAEGGGELGVHMYLLIFLKFVQAVIPTIEYDYTRHFTM
What is the function of this protein?
E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis.  Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A).  The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE).  This step is required for the membrane association of ATG8-like proteins.  The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt).  Preferred substrate is MAP1LC3A.  Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy.  ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3.  Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
What are the official names of this protein?
Ubiquitin-like-conjugating enzyme ATG3, Autophagy-related protein 3, APG3-like, hApg3, Protein PC3-96.
What is the protein family that this protein belongs to?
Belongs to the ATG3 family.
Protein: RS10_PYRNV
Sequence: MSLASRRKVRIRLYGTNPTDVDQVAREIVDLAKKMGVQVRGPIPLPTRRLMVTVRRAPSGQGYHTFDHWEMRISKRLIDIEASERVLRRLMTIRVPDTVKIELQLI
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNAK_METCA
Sequence: MAKIIGIDLGTTNSCVAILEGGKPRVIENSEGARTTPSIVAFTADNEVLVGQSAKRQAITNPKNTLFAIKRLIGRRYKDDVVQKDIKMVPYTIVEAENGDAWVEVGGKKMAPPEISARVLMKLKKDAEAYLGEEVKEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKSRGDQKIAVYDLGGGTFDISIIEIAEVDGEHQFEVLSTNGDTFLGGEDFDLRIIEYIVDEFRKEQGIDLHNDPLALQRLKESAEKAKIELSSSQQTEINLPYITADATGPKHLNVKLTRAKLEALVEDLILRTRGPCETALKDAGLKSADIDEVILVGGQTRMPKVQEFVKEIFGREPRKDVNPDEAVAVGAAIQAGVLGGQVKDVLLLDVTPLSLGIETLGGVMTKLIEKNTTIPTKATQVFSTAEDNQTAVTIHVLQGEREMARDNKSLGRFDLSDIPMAPRGVPQIEVTFDIDANGILNVSAKDKATGKQQSIVIRASSGLSEDEIKRMVKDAELHAEEDRRMHELVSARNHADAVVHATNKTLAELGDKVSGEERAKIEAALNDLKDAMGGDNKDLIEQRTSALTELSGKLAERLYTQQGGTAGSETHSHEKAGGSGGDDVVDAEFEEVRDDKR
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: 5051R_ASFP4
Sequence: MFSLQNLCRKTLPDCKLPEFFDEYILQLLGLYWENHGTIQRAGNNCVLVQQHTLIPVNEALRIAASEENYEIVSLLLAWEGNLYYAIIGALEGNRHDLIRKYDDQIKDHHEILPFIDNPVIFHKCHIMRRCFFDCILYQAVKYSKFRVLLYFKYRLENDLPLAHLLVEKACEDHNYEVIKWLYENLHIYNIMETFECAIAHKDLRLYRLGYTFIYNRIVPYKYHYLDVLILSGLHLLYKVAAKGYLDFILETLKYDHNNDNLDIILTQAVTYNHRKILTYYIPQLTYAQIEQCLFMAIKKKSSKKTLNLLLSHLKLSIKLIKKISQYVATYNSTNIIGILNMKRKKKIYLDIILTKFVKYAIFNKYVVRCMDTFSINPERIIKMAARINKMLLVKKISQHAWKNHAARLKHLKHAVYTMKHKDGKNRLMNLIYDHYYYHMQGEEIFSLARFYAIHHAPKLFDVFYDCCLLDTIRFKSLLLDCSHIIGKNAHDATNITIVNKYIGNLFAMGVLSKKEILQDYPSIYSKHYMP
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.
What are the official names of this protein?
Protein MGF 505-1R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 505 family.
Protein: MYO19_HUMAN
Sequence: MLQQVNGHNPGSDGQAREYLREDLQEFLGGEVLLYKLDDLTRVNPVTLETVLRCLQARYMADTFYTNAGCTLVALNPFKPVPQLYSPELMREYHAAPQPQKLKPHVFTVGEQTYRNVKSLIEPVNQSIVVSGESGAGKTWTSRCLMKFYAVVATSPASWESHKIAERIEQRILNSNPVMEAFGNACTLRNNNSSRFGKFIQLQLNRAQQMTGAAVQTYLLEKTRVACQASSERNFHIFYQICKGASEDERLQWHLPEGAAFSWLPNPERSLEEDCFEVTREAMLHLGIDTPTQNNIFKVLAGLLHLGNIQFAASEDEAQPCQPMDDAKYSVRTAASLLGLPEDVLLEMVQIRTIRAGRQQQVFRKPCARAECDTRRDCLAKLIYARLFDWLVSVINSSICADTDSWTTFIGLLDVYGFESFPDNSLEQLCINYANEKLQQHFVAHYLRAQQEEYAVEGLEWSFINYQDNQPCLDLIEGSPISICSLINEECRLNRPSSAAQLQTRIETALAGSPCLGHNKLSREPSFIVVHYAGPVRYHTAGLVEKNKDPIPPELTRLLQQSQDPLLMGLFPTNPKEKTQEEPPGQSRAPVLTVVSKFKASLEQLLQVLHSTTPHYIRCIKPNSQGQAQTFLQEEVLSQLEACGLVETIHISAAGFPIRVSHRNFVERYKLLRRLHPCTSSGPDSPYPAKGLPEWCPHSEEATLEPLIQDILHTLPVLTQAAAITGDSAEAMPAPMHCGRTKVFMTDSMLELLECGRARVLEQCARCIQGGWRRHRHREQERQWRAVMLIQAAIRSWLTRKHIQRLHAAATVIKRAWQKWRIRMACLAAKELDGVEEKHFSQAPCSLSTSPLQTRLLEAIIRLWPLGLVLANTAMGVGSFQRKLVVWACLQLPRGSPSSYTVQTAQDQAGVTSIRALPQGSIKFHCRKSPLRYADICPEPSPYSITGFNQILLERHRLIHVTSSAFTGLG
What is the function of this protein?
Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane (PubMed:19932026, PubMed:23568824, PubMed:25447992).  Motor protein that moves towards the plus-end of actin filaments (By similarity).  Required for mitochondrial inheritance during mitosis (PubMed:25447992).  May be involved in mitochondrial transport or positioning (PubMed:23568824).
What are the official names of this protein?
Unconventional myosin-XIX, Myosin head domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
Protein: OPSR_CARAU
Sequence: MAEQWGDAIFAARRRGDETTRESMFVYTNSNNTRDPFEGPNYHIAPRWVYNLATVWMFFVVVASTFTNGLVLVATAKFKKLRHPLNWILVNLAVADLAETLLASTISVTNQFFGYFILGHPMCIFEGFTVSVCGIAGLWSLTVISWERWVVVCKPFGNVKFDAKWASAGIIFSWVWSAIWCAPPIFGWSRFWPHGLKTSCGPDVFSGSEDPGVQSYMIVLMITCCIIPLAIIILCYIAVWLAIRTVAQQQKDSESTQKAEKEVSRMVVVMIFAYCFCWGPYTFCACFAAANPGYAFHPLAAAMPAYFAKSATIYNPIIYVFMNRQFRVCIMQLFGKKVDDGSEVSTSKTEVSSVAPA
What is the function of this protein?
Visual pigments are the light-absorbing molecules that mediate vision.  They consist of an apoprotein, opsin, covalently linked to cis-retinal.
What are the official names of this protein?
Red-sensitive opsin, Red cone photoreceptor pigment.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PROM1_MOUSE
Sequence: MALVFSALLLLGLCGKISSEGQPAFHNTPGAMNYELPTTKYETQDTFNAGIVGPLYKMVHIFLSVVQPNDFPLDLIKKLIQNKKFDISVDSKEPEIIVLALKIALYEIGVLICAILGLLFIILMPLVGCFFCMCRCCNKCGGEMHQRQKQNAPCRRKCLGLSLLVICLLMSLGIIYGFVANQQTRTRIKGTQKLAKSNFRDFQTLLTETPKQIDYVVEQYTNTKNKAFSDLDGIGSVLGGRIKDQLKPKVTPVLEEIKAMATAIKQTKDALQNMSSSLKSLQDAATQLNTNLSSVRNSIENSLSSSDCTSDPASKICDSIRPSLSSLGSSLNSSQLPSVDRELNTVTEVDKTDLESLVKRGYTTIDEIPNTIQNQTVDVIKDVKNTLDSISSNIKDMSQSIPIEDMLLQVSHYLNNSNRYLNQELPKLEEYDSYWWLGGLIVCFLLTLIVTFFFLGLLCGVFGYDKHATPTRRGCVSNTGGIFLMAGVGFGFLFCWILMILVVLTFVVGANVEKLLCEPYENKKLLQVLDTPYLLKEQWQFYLSGMLFNNPDINMTFEQVYRDCKRGRGIYAAFQLENVVNVSDHFNIDQISENINTELENLNVNIDSIELLDNTGRKSLEDFAHSGIDTIDYSTYLKETEKSPTEVNLLTFASTLEAKANQLPEGKPKQAFLLDVQNIRAIHQHLLPPVQQSLNTLRQSVWTLQQTSNKLPEKVKKILASLDSVQHFLTNNVSLIVIGETKKFGKTILGYFEHYLHWVFYAITEKMTSCKPMATAMDSAVNGILCGYVADPLNLFWFGIGKATVLLLPAVIIAIKLAKYYRRMDSEDVYDDVETVPMKNLEIGSNGYHKDHLYGVHNPVMTSPSRY
What is the function of this protein?
May play a role in cell differentiation, proliferation and apoptosis.  Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells.  During early retinal development acts as a key regulator of disk morphogenesis (PubMed:19228982).  Involved in regulation of MAPK and Akt signaling pathways.  In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
What are the official names of this protein?
Prominin-1, Antigen AC133 homolog, Prominin-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the prominin family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment. Note=Found in extracellular membrane particles in various body fluids such as ventricular fluid of the developing brain and urine.
Protein: COAD_XANC8
Sequence: MSVANSRTAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALPLERRVELAQEALAAHANVEVRGFDTLLAHFVRDMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVDALRQVRESRAQV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DHM1_METME
Sequence: MADADLDKQVNTAGAWPIATGGYYSQHNSPLAQINKSNVKNVKAAWSFSTGVLNGHEGAPLVIGDMMYVHSAFPNNTYALNLNDPGKIVWQHKPKQDASTKAVMCCDVVDRGLAYGAGQIVKKQANGHLLALDAKTGKINWEVEVCDPKVGSTLTQAPFVAKDTVLMGCSGAELGVRGAVNAFDLKTGELKWRAFATGSDDSVRLAKDFNSANPHYGQFGLGTKTWEGDAWKIGGGTNWGWYAYDPKLNLFYYGSGNPAPWNETMRPGDNKWTMTIWGRDLDTGMAKWGYQKTPHDEWDFAGVNQMVLTDQPVNGKMTPLLSHIDRNGILYTLNRENGNLIVAEKVDPAVNVFKKVDLKTGTPVRDPEFATRMDHKGTNICPSAMGFHNQGVDSYDPESRTLYAGLNHICMDWEPFMLPYRAGQFFVGATLAMYPGPNGPTKKEMGQIRAFDLTTGKAKWTKWEKFAAWGGTLYTKGGLVWYATLDGYLKALDNKDGKELWNFKMPSGGIGSPMTYSFKGKQYIGSMYGVGGWPGVGLVFDLTDPSAGLGAVGAFRELQNHTQMGGGLMVFSL
What is the function of this protein?
Catalyzes the oxidation of primary alcohols including methanol.
What are the official names of this protein?
Methanol dehydrogenase [cytochrome c] subunit 1, MDH large subunit alpha, MEDH.
What is the protein family that this protein belongs to?
Belongs to the bacterial PQQ dehydrogenase family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side. Note=Periplasmic, but associated with inner membrane.
Protein: DDL_STRE4
Sequence: MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFISQTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAETEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEVGLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAFKAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVRLAQEMFEKREGHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_GEOMG
Sequence: MIARLTGMLAHKSPDAIIIDVNGVGYRVQIPFSTYYELPDEGKTVSLSIYTHVKEDAISLFGFRTVAEKEFFQVLISVSGIGPKMARDILSNIQPDELAGAILQGNLVRLSSIPGIGKKTAERLVLELKEKVRKMDVAPSTKEAAPSEAPPEVADDVASALVNLGYKEAVVRKVLAEMAIESGASTEAVLRQALKILMK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: TAL_THEMA
Sequence: MKIFLDTANLEEIKKGVEWGIVDGVTTNPTLISKEGAEFKQRVKEICDLVKGPVSAEVVSLDYEGMVREARELAQISEYVVIKIPMTPDGIKAVKTLSAEGIKTNVTLVFSPAQAILAAKAGATYVSPFVGRMDDLSNDGMRMLGEIVEIYNNYGFETEIIAASIRHPMHVVEAALMGVDIVTMPFAVLEKLFKHPMTDLGIERFMEDWKKYLENLKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.  Does not show fructose-6-P aldolase activity.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CXIP4_ARATH
Sequence: MPATAGRVRMPANNRVHSSAALQTHGIWQSAIGYDPYAPTSKEEPKTTQQKTEDPENSYASFQGLLALARITGSNNDEARGSCKKCGRVGHLTFQCRNFLSTKEDKEKDPGAIEAAVLSGLEKIRRGVGKGEVEEVSSEEEEESESSDSDVDSEMERIIAERFGKKKGGSSVKKTSSVRKKKKRVSDESDSDSDSGDRKRRRRSMKKRSSHKRRSLSESEDEEEGRSKRRKERRGRKRDEDDSDESEDEDDRRVKRKSRKEKRRRRSRRNHSDDSDSESSEDDRRQKRRNKVAASSDSEANVSGDDVSRVGRGSSKRSEKKSRKRHHRKERE
What is the function of this protein?
May regulate CAX1 cation transporter.
What are the official names of this protein?
CAX-interacting protein 4.
What are the subcellular locations of this protein?
Nucleus.
Protein: CATNT_DEIRA
Sequence: MATPDGEQVWAQLQPQDRAWLNDLSRRAGPDTELALVGGAVRDALLGQTPLDLDIVVAGQDGQGVEALALASGLPFVFHPAFENATLTLPDGRGADLVRARREHYPQPGRNPEPLPGTLHDDLRRRDFGLNALALRLREDGAPELLDVVGGLRDLERRELRPLHDRSLHEDASRLVRAARLAARLELHPAPELLAQVPDALALADDTPRLWAELKLLLAEPRPGQAARVLDGWGAGTLLPGLPLLEALDVQQNAGTPVQPGTYAAAVLSAAPDAAALAERMALGERPAALLARALSDSYFAPGTPELQLRGLLRPESYLPLTGREVVALGVAPGPAVGRALAHLAGLRQSGAVRSADEERTALRAYLGANPKAT
What is the function of this protein?
tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus.  Adds the two cytidine residues to tRNA.
What are the official names of this protein?
CC-adding tRNA nucleotidyltransferase, C-adding TNT, CC-adding enzyme.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
Protein: Y1367_MYCTU
Sequence: MNLDGNQASIREVCDAGLLSGAVTMVWQREKLLQVNEIGYRDIDAGVPMQRDTLFRIASMTKPVTVAAAMSLVDEGKLALRDPITRWAPELCKVAVLDDAAGPLDRTHPARRAILIEDLLTHTSGLAYGFSVSGPISRAYQRLPFGQGPDVWLAALATLPLVHQPGDRVTYSHAIDVLGVIVSRIEDAPLYQIIDERVLGPAGMTDTGFYVSADAQRRAATMYRLDEQDRLRHDVMGPPHVTPPSFCNAGGGLWSTADDYLRFVRMLLGDGTVDGVRVLSPESVRLMRTDRLTDEQKRHSFLGAPFWVGRGFGLNLSVVTDPAKSRPLFGPGGLGTFSWPGAYGTWWQADPSADLILLYLIQHCPDLSVDAAAAVAGNPSLAKLRTAQPKFVRRTYRALGL
What are the official names of this protein?
Protein Rv1367c.
Protein: RS18_DICNV
Sequence: MARRKRICRFTAEGVKEIDYKDLETLKAYITEVGKIVPARITGTNVFYQRQLATAVKRARFLALLPYTDQH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.