PharMolix/UniProtQA huggingface dataset:
Protein: PAFA_ARTS2
Sequence: MDKRIFGIETEFGISYSSPDSRPLAPEEVARYLFRKVVSWGRSSNVFLTNGSRLYLDVGSHPEYATAECDDLGQLIAHDRAGELILDDLVDEAQERLAAEGFNGTVYLFKNNTDSAGNSYGSHENYLIPRRGEFSRLAEILIPFLVTRQLIAGAGKILKTPHGATFAFSQRADHIWEGVSSATTRSRPIINTRDEPHADAEFYRRLHVIVGDSNMSETTALMKVGTVDLILRMIEAGVIMRDMRMENPIRSIREISHDLSGRALIRLANGRQLTALEIQREYLNKVTSFVAENGAHNQHVPLILDLWERTLTAIESGDTSTIDTEIDWAIKKKLMDSYRKRHGLGLDAPRIAQLDLTYHDISRTRGLYYLLQSRGAVRRVVDDTAVKDAVDAPPQTTRAKLRGDFVRRAQELGRDYTVDWVHLKLNDRAHQTILCKDPFRNVDERVDALLDSMG
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: ATPF_SHISS
Sequence: MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIVAQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: 149L_IIV6
Sequence: MKETIFEIFVDDLMDSSYDEEDFERGDAGIDDKKAFMKNQFRTISLAEKNSLVQRTMKLYEAGALNKRVMDKATLVEQNTYIPSHKEIDKYENDTVPIPVAKPKNPHVDEPAFNVNEIMGRADKYIGTFNLGMVWVYPYLDDPPIKFGTRTLEHKFEYDLLSPANDSTMLNIENKLYPSISHYLIVRVAQTMPGFENVDKAYGVISDGPNRFFSVADSESRLMNLEQTVFSKEKTFLLQKAIRNKFDQRKFKDILIATGDKVLVYAPLKLTDEARRLKYQGLAKPINIVTESNAYRKETTNFLEKIRPTILPEDVIFSNNNAFKTSLEYDEFMEMFMVEKVKDISFTIKCVQVFCKHKDLPFSLTKCFVKKVLESFYGECTPVNYISGSAKKQYPYRFEEALSAQFQIRSRKETSFSMSTKTANLIFNKILETLFNLENVMKNGELPHIGGQNEIPMYATLFKIALMDSQWLLSKRNNKDLKFDTKSKNNNNIISAIINVISILHMDLSDNKKVGNCIYDSIDNIVDDVDIKIATSILTGKIQPLEEITVAKSKGSLRAQIIAEEEIRFGEEIEAEFNDEEVVEEGDVIEEEELDEEGGEEEEGIDYADELPEFDEEAYYEGVVRTITGHFESLGLDVENGIEDKIRKEAQKIEKIGNRLKINFYA
What are the official names of this protein?
Uncharacterized protein 149L.
Protein: MPAG_PENRF
Sequence: MLTKSVTSILQGITLAAKEFENNEAGARESLIAHSRALISALEVPSEFIQHTFWSQPALSAIIRLAADVNMFQHLKDAAGKGIDCEALSMKTGVDASLLSRLARHLVAMNVITFQNGAFHGTDLSDSLAAENYQHSIRFCHDVSRPSFNEFPEFFKSNGYKTPTLSGTDGPFQAAHKTELTFLQWLVNTHPYLQYFHSYMSVYRAGKQNWCDTGFYPVSERLLSGFDASVSDVVLVDVGGGRGHDLETFASKFSPLPGRLVLQDREQTIASMPADESRQFEATAHNIFTPQPVKYARAYYMHSVPHGFGDEDAIKIMANLVPALAKGYSRVLLNEIVVSEENPILAATNMDMIMLAHLAVKERTEAEWRYIFTQAGLKVVNIYSYPGVAESLIEAELA
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 (PubMed:26751579).  MpaC methylates farnesyl-DHMP-3C (FDHMP-3C) to yield MFDHMP-3C (By similarity).  The first step of the pathway is the synthesis of 5-methylorsellinic acid (5MOA) by the cytosolic polyketide synthase mpaC.  5MOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) by the endoplasmic reticulum-bound cytochrome P450 monooxygenase mpaDE.  MpaDE first catalyzes hydroxylation of 5-MOA to 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid (DHMB).  MpaDE then acts as a lactone synthase that catalyzes the ring closure to convert DHMB into DHMP.  The next step is the prenylation of DHMP by the Golgi apparatus-associated prenyltransferase mpaA to yield farnesyl-DHMP (FDHMP).  The ER-bound oxygenase mpaB then mediates the oxidative cleavage the C19-C20 double bond in FDHMP to yield FDHMP-3C via a mycophenolic aldehyde intermediate.  The O-methyltransferase mpaG catalyzes the methylation of FDHMP-3C to yield MFDHMP-3C.  After the cytosolic methylation of FDHMP-3C, MFDHMP-3C enters into peroxisomes probably via free diffusion due to its low molecular weight.  Upon a peroxisomal CoA ligation reaction, catalyzed by a beta-oxidation component enzyme acyl-CoA ligase ACL891, MFDHMP-3C-CoA would then be restricted to peroxisomes for the following beta-oxidation pathway steps.  The peroxisomal beta-oxidation machinery than converts MFDHMP-3C-CoA into MPA_CoA, via a beta-oxidation chain-shortening process.  Finally mpaH acts as a peroxisomal acyl-CoA hydrolase with high substrate specificity toward MPA-CoA to release the final product MPA (PubMed:26751579) (Probable).
What are the official names of this protein?
O-methyltransferase mpaG, Mycophenolic acid biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: ZN674_HUMAN
Sequence: MAMSQESLTFKDVFVDFTLEEWQQLDSAQKNLYRDVMLENYSHLVSVGHLVGKPDVIFRLGPGDESWMADGGTPVRTCAGEDRPEVWEVDEQIDHYKESQDKFLWQAAFIGKETLKDESGQECKICRKIIYLNTDFVSVKQRLPKYYSWERCSKHHLNFLGQNRSYVRKKDDGCKAYWKVCLHYNLHKAQPAERFFDPNQRGKALHQKQALRKSQRSQTGEKLYKCTECGKVFIQKANLVVHQRTHTGEKPYECCECAKAFSQKSTLIAHQRTHTGEKPYECSECGKTFIQKSTLIKHQRTHTGEKPFVCDKCPKAFKSSYHLIRHEKTHIRQAFYKGIKCTTSSLIYQRIHTSEKPQCSEHGKASDEKPSPTKHWRTHTKENIYECSKCGKSFRGKSHLSVHQRIHTGEKPYECSICGKTFSGKSHLSVHHRTHTGEKPYECRRCGKAFGEKSTLIVHQRMHTGEKPYKCNECGKAFSEKSPLIKHQRIHTGERPYECTDCKKAFSRKSTLIKHQRIHTGEKPYKCSECGKAFSVKSTLIVHHRTHTGEKPYECRDCGKAFSGKSTLIKHQRSHTGDKNL
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 674.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FXL15_MOUSE
Sequence: MEPPMEQSGGEQEPGAVRLLDLPWEDVLLPHVLNWVPLRQLLRLQRVSRAFRALVQLHLARLRRFDAAQVGPQIPRAALARLLRDAEGLQELALAPCHEWLSDEDLVPVLARNPQLRSVALAGCGQLSRRALGALAEGCPRLQRLSLAHCDWVDGLALRGLADRCPALEELDLTACRQLKDEAIVYLAQRRGAGLRSLSLAVNANVGDTAVQELARNCPQLEHLDLTGCLRVGSDGVRTLAEYCPALRSLRVRHCHHVAEPSLSRLRKRGVDIDVEPPLHQALVLLQDMAGFAPFVNLQV
What is the function of this protein?
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway.  Required for dorsal/ventral pattern formation and bone mass maintenance.  Also mediates ubiquitination of SMURF2 and WWP2 (By similarity).
What are the official names of this protein?
F-box/LRR-repeat protein 15, F-box only protein 37.
What is the protein family that this protein belongs to?
Belongs to the FBXL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_LEPBP
Sequence: MKRGKKYIQLKEKVDRTKAYTLGEAVGLAKATSYSKFDGTLEISTKINYKSLQNVRGTISLPHGTGKTIKVLVFCKGDKQNEAREAGADFVGDMDLIEKVSGGWTDFDACVATPDMMKEVGKLGPVLGRKGLMPKPKAGTVTTDVSKAVKELKAGRIEYRPDKGGVVHLGVGKCSFSDDKLSDNINAVVAALMKDKPSDAKGDYLKSFSVAATMGIGVKVDVKELVNANI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: Y954_STAS1
Sequence: MAVNLYDHANQLEQALRESDEYQAIQNAYAKVKENQESKDLFDEFRETQLSFQQKQMQGEEIGEEELQKAQEQAQKIENDSNISELMAAEQNMSQVFQEINQIIVKPLDEIYAD
What are the official names of this protein?
UPF0342 protein SSP0954.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: ITPK2_ORYSJ
Sequence: MRLHGEVSFDEDEEEVVMVPAAALSSSPLNGGAVPVTRLVVGYALTKKKVKSFLQPNLLLLARKKGINLVAIDDTRPLAEQGPFDVILHKITSKEWQQVLEDYHEEHPEVTVLDPPNAINHLNNRQSMLAEVSDLNLSSFYGEVCTPRQLVIMRDPSSIPTAVAMAGLTLPLVAKPLVVDGTSKSHELSLAYDEASLSMLDPPLVLQEFVNHGGILFKVYIIGETIQVVRRFSLPDVNTYDLLNNVGVYRFPRVSCAAASADHADLDPHISELPPRPLLEKLGKELRGRLGLRLFNIDMIRELGTKDRYYIIDINYFPGFGKMPGYEHIFTDFLLNLAQSKYKKCLSGG
What is the function of this protein?
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3 and participates in phytic acid biosynthesis in developing seeds.  Phytic acid is the primary storage form of phosphorus in cereal grains and other plant seeds (By similarity).  May be involved in the negative regulation of osmotic stress signaling (PubMed:18421420, PubMed:22038091).
What are the official names of this protein?
Inositol-tetrakisphosphate 1-kinase 2, Inositol 1,3,4-trisphosphate 5/6-kinase 2, Inositol-triphosphate 5/6-kinase 2, Ins(1,3,4)P(3) 5/6-kinase 2, OsITP5/6K-2, OsITPK2, OsITL1, Protein DROUGHT- AND SALT-SENSITIVE MUTANT 3, OsDSM3.
What is the protein family that this protein belongs to?
Belongs to the ITPK1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: DF116_ARATH
Sequence: MAITKNMLVVLLLTIIFVTSSVHCSDSALGIGIKEDWEVCFSIDPCLTGEGTLGCTKWCRNHINLSLVGYCRTDPEHCCCVAEK
What are the official names of this protein?
Defensin-like protein 116.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOA_BACVZ
Sequence: MIEIEKPKIETVEISDDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVTSIQIDGVLHEFSTIEGVVEDVTTIILHIKKLALKIYSDEEKTLEIDVQGEGTVTAADITHDSDVEILNPDLHIATLGENASFRVRLTAQRGRGYTPADSNKRDDQPIGVIPIDSIFTPVSRLSYQVENTRVGQVANYDKLTLDVWTDGSTGPKEAIALGSKILTEHLNIFVGLTDEAQHAEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVQELANKTEEDMMKVRNLGRKSLEEVKAKLEELGLGLRKDD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: DFAM2_LYMST
Sequence: PYDRISSSAFSDF
What are the official names of this protein?
Lymna-DF-amide 2.
What are the subcellular locations of this protein?
Secreted.
Protein: RR7_CALFG
Sequence: MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIVYQAVKKIQQKTETNPLSVLRQAICRVTPDIAVKARRVGGSTHQVPIEIGSTQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PABA_STRLI
Sequence: MTSVLMIDNCDSFTYNLVDQFSPHGTIVIVKRNHPFYDGEIEAIMALTSICITPGPCYPAEAALNSCSIIGHLAGRIPILGICLGQQALGQARGGLVIFAHGKLSNIEHNGIFAPLFNPPRALPAGRYHSLVVEPARIEVTGQCNQLEVVPQEIMAIRHRDLPVEGVQFHPESILSSNGAAILANLIHRPCH
What is the function of this protein?
Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p-aminobenzoate (PABA) and tetrahydrofolate.  In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC.  PabA converts glutamine into glutamate only in the presence of stoichiometric amounts of PabB (By similarity).
What are the official names of this protein?
Aminodeoxychorismate synthase component 2, ADC synthase, ADCS, 4-amino-4-deoxychorismate synthase component 2, Aminodeoxychorismate synthase, glutamine amidotransferase component.
Protein: CY24A_BISBI
Sequence: MGQIEWAMWANEQALASGLILITGGIVATAGQFTQWYLGAYSIAAGVLVCLLEYPRGKRSKGSTMERCGQKYLTRVVKLFGPLTRNYYIRAFLHLGLAVPAGFLLATILGTACLAIASGIYLLAAIRGEQWSPIEPKPKERPQIGGTIKQPPSNPPPRPPAEARKKLSEEAAGVPTGGPQENPMPVNDEVV
What is the function of this protein?
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.  Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
What are the official names of this protein?
Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox.
What is the protein family that this protein belongs to?
Belongs to the p22phox family.
What are the subcellular locations of this protein?
Cell membrane. Note=As unassembled monomer may localize to the endoplasmic reticulum.
Protein: LPXB_ARATH
Sequence: MMFQITKSKLRFPLSTFTKRYSSFQAAKSVIDKAAIDGELRVFIVSGEVSGDNIGSRLMSSLKKLSPLPIRFNGVGGSLMCKKGLNSLFPMEDLAVMGVWELLPHLYKFRVKLKETIDAAVKFKPHVVVTVDSKGFSFRLLKELRARYKQQRLENCSVHFHYVAPSFWAWKGGESRLGGLSEFVDHLFCILPNEERVCREHGVEATFVGHPVLEDASEFDLVRRCKPQELKLEGLSFSEHSIPSDSTVISVLPGSRLQEVERMLPIFSKAMKLLKDPFPKLVTLIHVASNNQVDHYIGESFSEWPVPAILVPSGSTQLKYDAFGASQAALCTSGTVAVELQLAHLPSLVAYRAHFLTELLIRYKAKIPYISLPNILLDSPIIPEALFQACNPSNLASILERLLLDEKMRERQVVGAEKLIQLLHPSESRMGNSIHCTGLESHRYTPSILAASTILSYARR
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell.  Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential).
What are the official names of this protein?
Probable lipid-A-disaccharide synthase, mitochondrial, Protein LIPID X B, AtLpxB.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: S12A4_HUMAN
Sequence: MPHFTVVPVDGPRRGDYDNLEGLSWVDYGERAELDDSDGHGNHRESSPFLSPLEASRGIDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGTRRRAAEAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGAHDTSNATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYAGGIKSIFDPPVFPVCMLGNRTLSRDQFDICAKTAVVDNETVATQLWSFFCHSPNLTTDSCDPYFMLNNVTEIPGIPGAAAGVLQENLWSAYLEKGDIVEKHGLPSADAPSLKESLPLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIITTSLVYFSSVVLFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKVNGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMLIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCRMRIFTVAQMDDNSIQMKKDLAVFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTEREREAQLVKDRHSALRLESLYSDEEDESAVGADKIQMTWTRDKYMTETWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPRNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS
What is the function of this protein?
No transporter activity.
What are the official names of this protein?
Solute carrier family 12 member 4, Electroneutral potassium-chloride cotransporter 1, Erythroid K-Cl cotransporter 1, hKCC1.
What is the protein family that this protein belongs to?
Belongs to the SLC12A transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RS4_KARMG
Sequence: MARYIGPKTKISRKFGELIYGKTNKSFEKKKYPPGNSSSRNIKKTFYSTQLLEKQKIKYTYGILERQFLKMFYKASKKKGIKGEILLQLCESRLDNIVYRLNLSHSRPEARQLVSHRHITVNGKIVNIPSFNLKPGDKISLKEKHKHKANKNKLLGSDWLSWDNEKMIGIFKYIPNRNQITENINEKLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: YFDR_ECOLI
Sequence: MSFIKTFSGKHFYYDKINKDDIVINDIAVSLSNICRFAGHLSHFYSVAQHAVLCSQLVPQEFAFEALMHDATEAYCQDIPAPLKRLLPDYKRMEEKIDAVIREKYGLPPVMSTPVKYADLIMLATERRDLGLDDGSFWPVLEGIPATEMFNVIPLAPGHAYGMFMERFNDLSELRKCA
What are the official names of this protein?
Uncharacterized protein YfdR.
Protein: AER_ECOLI
Sequence: MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLPLRWRARGVMTLMFILLAAMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVAHQALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH
What is the function of this protein?
Signal transducer for aerotaxis.  The aerotactic response is the accumulation of cells around air bubbles.  The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state.  It uses a FAD prosthetic group as a redox sensor to monitor oxygen levels.
What are the official names of this protein?
Aerotaxis receptor.
What is the protein family that this protein belongs to?
Belongs to the methyl-accepting chemotaxis (MCP) protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein. Note=Predominantly localized to one cell pole in mid-to-late exponential phase, with a few smaller foci elsewhere in the cell.
Protein: RS5_DESVV
Sequence: MEQNEFGLIEKIVYLNRVAKVVKGGRRFSFSALVVVGDGKGSVGFGLGKAQEVPEALRKATERAKKSMIEVPLIDGTLPYEILGRFGAGHVLLKPASKGTGIIAGGAVRAVMEAVGVTDVLTKAIGTNNPHNVLRATVAGLASLRSAEEVGQLRGKKLEAPRK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NPD_XANCP
Sequence: MTVAITQTGPALQEFVERHQRLFVLSGAGCSTDSGIPDYRDLQGGWKRPQPVTFQAFMGELSTRQRYWARSLVGWPRFGLARPNATHHALAALEARGQLELLLTQNVDRLHQAAGSQAVIDLHGRLDVVRCMGCEQRMPRTEFQLLLERDNPGWADLEAAQAPDGDADLDNVAFDNFVVPACPACGGVLKPDVVFFGENVPRERVERAFAHLQAADAVLVVGSSLMVYSGFRFVQAAARAGLPIAALNFGRTRADDLLSLKVEQSCAQALAFLQQPPDPLHTATARYHSARSA
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ORF3_HEVMY
Sequence: MGSRPCDLGLFCCCSSCFCLCCPRHRPVSRLAAVVGGAAAVPAVVSGVTGLILSPSQSPIFIQPTPSPPMSPLRPGLDLVFANQPDHSAPLGVTRPSAPPLPHVVDLPQLGPRR
What is the function of this protein?
Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  Acts also as a viroporin and forms ion conductive pores allowing viral particle release.  Impairs the generation of type I interferon by down-regulating host TLR3 and TLR7 as well as their downstream signaling pathways.  Down-regulates the phosphorylation of host IRF3 via the interaction with host SIRP-alpha, thereby inhibiting IFN-I expression.  Interacts with host microtubules.
What are the official names of this protein?
Protein ORF3, pORF3.
What is the protein family that this protein belongs to?
Belongs to the hepevirus ORF3 protein family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane. Host cytoplasm. Note=The N-terminal region seems to associate with the cytoskeleton probably via one of its hydrophobic regions.
Protein: Y1397_BACVZ
Sequence: MTKKIGIEQSLSDVEQALKQKGYDVVMMKTPEDAKNCDCCVVTGLDSNVQGIADTSTQAPVITASGMTADEICSEVEKKFH
What are the official names of this protein?
UPF0180 protein RBAM_013970.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: RECF_STRMU
Sequence: MWIEKINLKHYRNYTAIESEFSQSLNVFVGQNAQGKTNFLEAIYFLSLTRSHRTRSDKELIQFGQKELNVSGLLNRVNGKIPLEINLSNKGRTTKINYLKQPKLSDYIGTMTVVLFAPEDLQLIKGSPSLRRKFIDIDLGQIKPIYLSDLSNYNHVLKQRNAYLKSEKKVDTDFLFVLDEQLVDYGSKVIEHRLDFIQNLTKEADKYHFSISNQQEHLKISYLSSVKFDHKKNIRDNFLNLLQKNRQGDIFKKNTSVGPHRDDLAFFINQMNASFGSQGQHRSLILSLKLAEIELTKTVTGDYPILLLDDVMSELDNYRQIKLLEGIKDNVQTFITTTSLEHLQQLPKKLKLFTINQGKVLSE
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_DROME
Sequence: MPAPVVKKPAAKKLPAVPESKLKFSKKQISKRVAESKRRLKKAAVIALRKKENLVRAEKYQNEYIKAEQREIKLRRLAKKRNQFYVPAEAKLAFVVRIRGINKVAPKVRKVLQLFRLRQINNGVFIKLNKATINMLRIAEPYITWGYPNLKSVRELIYKRGFVKHNRQRVPITDNFVIERKLRQAHQIQCVEDLVHEIFTVGPNFKYASNFLWPFKLNTPTGGWRKKANHYVNGGDFGNREDQINRLLRKMV
What is the function of this protein?
Binds to G-rich structures in 28S rRNA and in mRNAs.  Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs (By similarity).
What are the official names of this protein?
60S ribosomal protein L7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.