PharMolix/UniProtQA huggingface dataset:
Protein: TRUB_PYRFU
Sequence: MARDEVRRILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLWEKRDRS
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
Protein: BPPBF_BOTCO
Sequence: QNAHPSPKVPP
What is the function of this protein?
This peptide evokes slight hypotension (-2 mmHg), when injected alone into rats.  It has a bradykinin-potentiating effect (75%), when 60 nmol of BPP-11f are coinjected with 0. 5 ug of bradykinin into rats.  It inhibits angiotensin converting enzyme (ACE) activity with a K(i)app of 82. 10 uM.
What are the official names of this protein?
Bradykinin-potentiating peptide 11f, BPP-11f.
What is the protein family that this protein belongs to?
Belongs to the bradykinin-potentiating peptide family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMH_SHELP
Sequence: MTQEFAHLSVLLTETVAGLNIKPEGIYIDGTFGRGGHSREVLKQLGPNGRLIAIDRDPQAIAAAEQFADDARFSIVHGGFGQLAQYVDDLGLRGKIDGILFDFGVSSPQLDDAERGFSFLRDGPLDMRMDNSQGETAAEWLARAEIEDMAWVFKTYGEEKNARHIARCIAADRDKTPFLRTKELADLIARVSKSKERNKHPATRVFQAIRIYINSELEQIDQALEGAVTVLAPQGRLSVISFHSLEDRMVKRFIRRHSQGESVPHGLPLTEAEINKTRLLKAVGKAIKPSAEEIDRNARARSSVLRVAERLDY
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_BORDL
Sequence: MGKDIKDEILSLRDAIKKWDREYYVDSSPTVGDVTYDKALLRLQYLENRYPEYKTLDSPTLKFGSDLLNDFKEVEHSYPILSLDKAYDVKELLLWVEKMSLEGSNLGFDMGISAEPKIDGCSIVLYYKDGILEKALTRGDGRFGNNVIENVRTIKNVPLCIGERVELVLRGEIYITKKDFLKINHTLDDSYINARNLTSGILRRINSREVVNFPLDIFVYDILYSSLELNTNHDAFDKLKHFGFKLNPFCKFFCGKNLGENIINYVKEIEEQRERFEYEIDGVVLKVDDFRLRDVLGYTSHHPKWSIAYKFESLRAVSKVIDIVVQVGRSGKITPVANIEKVLIAGAFITSASLHNQDYIDSIGLNVKDVVAISRRGDVIPAVELVVEKLSVGNFKIPNYCPSCKKSLIKEGAHLFCVNIHCPLKIMGHIKYFCSKKCMNIVGLSEKTIEFLFNMNFISSEIDLYTFDFDRLIGLKGFNFKRVNKLKRSIEESKNRPFKKLLLAMGIKDLGINTILLLINNNLNSFDAISLLCQDNKNALVKLLDIKGIGERIAFNIIRAFNDKIILDKFNFFKGLGFKMQEDSINCVVDSSFLFGKKFCITGSFDEYPRHVLIDKITKKGAIFNSSVSRYLDFLLVGKSPGLKLKKANNLGIKILSLFDIKNLVNLDD
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: YBJQ_ECO5E
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: DAPA_WOLPP
Sequence: MKSTFLWTACVTPFNCSGDSIDYQSLQRLLTMQAETENGVVLLGSTGESLSLTDSEKRTLVEFVCELKLNTKIIIGVPGVNLYQTLEWLDFCKGMPIHGYLMTTPIYAKPGIMGQTLWFEKLLEKAHVPAMLYNIPSRAGVSLHAETVRNLSSHEKFWAIKDSSGTVDTLTQYKKVAPNIEVFCGDDNMIPDMAAKGAAGLVSVAANVWPSVVHEYVKQCMSGENPQADSWQQACKTLFTASNPIPTKALLHDIGLIEHKTVRLPLSTEDLPSIETLRQANKMILGWKELTNS
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P53_MACMU
Sequence: MEEPQSDPSIEPPLSQETFSDLWKLLPENNVLSPLPSQAVDDLMLSPDDLAQWLTEDPGPDEAPRMSEAAPPMAPTPAAPTPAAPAPAPSWPLSSSVPSQKTYHGSYGFRLGFLHSGTAKSVTCTYSPDLNKMFCQLAKTCPVQLWVDSTPPPGSRVRAMAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYSDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENFRKKGEPCHQLPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFEMFRELNEALELKDAQAGKEPAGSRAHSSHLKSKKGQSTSRHKKFMFKTEGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: CWZF7_ORYSJ
Sequence: MLSVRRRQEDARGVGLRGGAAAGGMEDDAELEEGEACGDETAFVDPDVALSYIDEKIQDVLGHFQKDFEGAVSAENLGSKFGGYGSFLPTYQRSPLPQTRSPPKAANVSSRSPYHQPTESMSQNTLAVAAPSVSKHNGSMVPLSDDSSKKEVHQSTKVERASSTQDSLNGLSKSSDHNRFKVRIKVGSDNGLARNNAAIYSGLGLDISSPSSIEDSPDGCGSLSPEFNNVPIESPRTILQIMTCFSVPGGFLLSPLRDDLVQLTQKVVPTSKKWETNANTENVQERYEGYAAKRVKSDAKKKKAVDTKRSKSRNDVSAVMKNEIDIETPAGQKIVLEALNIPLLSNPRTMEAKDGSQFEEDPMRDTLVENKDARLKERTINSDLMAIKYENVKAEAAECLENSGPGSSGMDFSAVKGEVKFKAEKAEIHVEDRNTTSEKDFQSDRKQERKIKTESKCNATGVNFEGNKVMNERTPVVGRSIGKVSSKETLLNDINEENVSKSESRRSQKEQNMNASSSSDFLEDDRGVLSSGAVKERKNDSQSKSSHPGRKPKAKSHRDVREHLPEGSYGGKDDTLENGSGLGELRPKKIWKNDSERDSDMPGTSKREISSSLKNDRHTPAEEQRMHVPPSVSAPTANAAPMLPAPVVIEEHWVCCDICQKWRLLPYKMNPSLLPKKWKCSMLQWLPGMNRCEVSEDETTNALNALYVSPAPGNGVASVGHSHVASSGLTTSNTLNVNGHVEQSRKRKNTLSDGNVSFDVSQQMQGSVYPLSNQHAPIRSKSAADSIQFPVERDSKSVDHFVEKKRSKSKNHGSSSDGGHLVERSKKHSKVKSKREMDHDEYRTSKKIKKEERRQRQSGIDSNPGYDLASGDVPDEAKALPSKSMALQGSSERSDVPPSKYKSVSKYNSSEKSKRSKDGDVFLPEDKNKEHSYPSDAQKPDLSSKKRIVKEWEESQHNSTPPVSKMSIVNQSSSSKETCKDQNLKETKSKLTKSEEPFAMTDSKSIKVAHSNQTSRNLNNELFEDSTPFAVKSGMSEPPENRSSEQALDLAEPASSDLAYFQTTAVTSSSSKASGSQRRKQNFHVAKTSPIESVSSSPPRISNNDKVSHDKILGKDGSTCANTNNMQSLVKNTEVIVDNVRQARKSHESMLASEPVMNGFSQGNSDKDNELPQLTQGHASNGIISGRSLDDDLQHASGRKDSSLKSSNAARSHNHLHYANKNNLLTDGSSIQHRMAVLDTKGDSMVHENKRSVTSLQDRNGSTHYPPDGNPQSEVSFGKEKSHPKSNKHDMQNSKAQMLPSPLKESKVESHSAPLRSNASKLTAQLKRGNVENGGQHGITKQAISNPADTSSPVRKDNNSTGYALKEARDLKHKANRLKEEGKEQESTRLYFESALKYLHVASTLEPPPSIDGFKQCDAAQNLYSDTAKLCNFVGHAYEKSKKMAAAALAYKCVEVAYLKAAYYKYPTASKDRQMLQAIVQNPPGESPSSSASDIDNLNNNGLSKGPSSKDANSPQVTGNNLLLAARNQPHLTRLLAYTNDVNCAFDATRKSQMAIASAASNQENGIDGLSSVKTVLDFNFQSVNDLLRLVRLSMESISC
What is the function of this protein?
Transcriptional activator that acts as a positive regulator of grain size (PubMed:31830332).  Binds directly to the DNA core sequence 5'-CATTTC-3' found in the promoter of MADS1, and activates MADS1 transcription (PubMed:31830332).  Increases grain width via direct up-regulation of MADS1 expression (PubMed:31830332).  Promotes active chromatin modification at the MADS1 locus by increasing its level of histone H3K4me3 (PubMed:31830332).  In GST pull-down assay, binds specifically to histone H3K4me3, but not to H3K4me1 or H3K4me2 (PubMed:28818372).  May facilitate the recruitment of effectors to mediate gene expression (PubMed:28818372).
What are the official names of this protein?
Cysteine-tryptophan domain-containing zinc finger protein 7, OsCW-ZF7, Protein WIDE GRAIN 7.
What are the subcellular locations of this protein?
Nucleus. Note=Exhibits a speckle-like distribution in the nucleus.
Protein: AMY_BACAM
Sequence: MIQKRKRTVSFRLVLMCTLLFVSLPITKTSAVNGTLMQYFEWYTPNDGQHWKRLQNDAEHLSDIGITAVWIPPAYKGLSQSDNGYGPYDLYDLGEFQQKGTVRTKYGTKSELQDAIGSLHSRNVQVYGDVVLNHKAGADATEDVTAVEVNPANRNQETSEEYQIKAWTDFRFPGRGNTYSDFKWHWYHFDGADWDESRKISRIFKFRGEGKAWDWEVSSENGNYDYLMYADVDYDHPDVVAETKKWGIWYANELSLDGFRIDAAKHIKFSFLRDWVQAVRQATGKEMFTVAEYWQNNAGKLENYLNKTSFNQSVFDVPLHFNLQAASSQGGGYDMRRLLDGTVVSRHPEKAVTFVENHDTQPGQSLESTVQTWFKPLAYAFILTRESGYPQVFYGDMYGTKGTSPKEIPSLKDNIEPILKARKEYAYGPQHDYIDHPDVIGWTREGDSSAAKSGLAALITDGPGGSKRMYAGLKNAGETWYDITGNRSDTVKIGSDGWGEFHVNDGSVSIYVQK
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOLB_VIBCM
Sequence: MFKRLVFVLMLIGTGFSNIANAALELVITDGIDSARPIAIVPFKWEGATKLPEDVSAVIASDLQRSGKFSPVPTSKMPQTPYSEEQVNFGKWTSMGVDSLLTGTITQNAEGSYVISYQLVDIVRGQLTQGQSKALSQDGQLVLSKDHVLFNKVATVPASRMREYAHRIADLVYEELTGERGAFLTRIAYVVVNDKDPYPYQLRIADYDGYNERLVLRSKQPLMSPAWSPDGQTLAYVSFQNGQAEIYMMNIYSGKREKLTSFPRHNGAPRFSPDGKTLALVLSKTGNLQVYTMDLATRRLTEVTSGRSNNTEPFWHPDGKSLIFTSDRGGKPQIYQVNLSGGETKRLTWQGSQNLGGQITPDGKFLVMVNRSDSGFNLAKQDLETGAMQILTKTLLDESPSIAPNGGMVIYSSIYNKANVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RBS2_SOYBN
Sequence: MASSMISSPAVTTVNRAGAGMVAPFTGLKSMAGLPTRKTNNDITSIASNGGRVQCMQVWPPVGKKKFETLSYLPDLDDAQLAKEVEYLLRKGWIPCLEFELEHGFVYREHNRSLGYYDGRYWTMWKLPMFGCTDASQVLKELQEAKTAYPNGFIRIIGFDNVRQVQCISFIAYKPPSF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 2, RuBisCO small subunit 2, Ribulose bisphosphate carboxylase small chain 4, chloroplastic, RuBisCO small subunit 4.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DCDB_STRAW
Sequence: MLLSDKDIRAEIDAGRVRIDPYDESMVQPSSIDVRLDRYFRVFENHRYPHIDPSVEQADLTRLVEPEGDEPFILHPGEFVLASTYEVISLPDDLASRLEGKSSLGRLGLVTHSTAGFIDPGFSGHVTLELSNLATLPIKLWPGMKIGQLCMFRLSSPAEFPYGSDRYGSRYQGQRGPTASRSFLNFHRTQV
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: GPMA_BAUCH
Sequence: MTLNKLVLIRHGESKWNNENRFTGWTDIDLSDQGRIEAKNAGQLLKQAGFIFDFAYTSVLKRAIHTLWYILDELDQAWLPVEKSWRLNERHYGALQGLNKKKITVEYGEEQVQQWRRSLNITPPELSDNDKRLPIYDIRYAKLSLDQLPKAESLAMTINRIIPYWKGEILPRINNGERVIIAAHGNSIRAIITLLDQLSENELIQLNIPTGVPIIYEFNSQIKTIKHYYLSIVNKDY
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: CHEB_PSEA6
Sequence: MAYKILVVDDSIFFRRRVKEILEQDPSLQVIGEARNGQEAIEMVATLNPDVVTMDVEMPIMDGITAVKKIMARKPVPIIMFSSLTLQGAKATLDALDSGAMDFLPKKFEDIAANRQDAVALLQSRVKSLCRKQHGLRPASVRVAPPKAILFNKPVSRNPAKRSVQATSSIPLGAPLYHSSSSGIPSGKKYRCLAIGTSTGGPVALQKVLTAVPKNFPYPIFIVQHMPGSFTKAFAERLNQLSQLTVKEAMNGEEVKAGVAYLAPGGRQMTVQGDSQRVSFRIYDAPDSADILYKPCVDITFASIAHVYHGDVLGVILTGMGSDGKLGASKLKSKGAKIWVQDELSSVVYGMPQAVMNAGIAEKEFSIDAFESHILKEMA
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_ENT38
Sequence: MSSKEQKTPEGQAPEEIITEQHEEVEAVEPDASAEQVDPRDEKIANLEAQLTEAQNREREGVLRVKAEMENLRRRTELDVEKAHKFALEKFVNELLPVIDSLDRALEVADKANPDMTAMVEGLELTLKSMLDVVRKFGVEVVAETNVALDPNVHQAIAMVESEDVAAGNVLAVMQKGYTLNGRTIRAAMVTVAKAKG
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALCA_BORBR
Sequence: MNREIYDFVAIGIGPFNLSLASLSAPLRGVRTLFLDKKSGFDWHPGMLIETSTLQNPFLADLVSLADPRSEYSYLNYCKLTNRIYSYYMRENHYLSRAEYTRYCQWVAARLPNLRFGCDVQGVLHDPESHSYLVTGQHTMSGQRFMFRCRKLVLGLGSQPYLPACCDRRAAPFIHSADYLRHKYELQGRASITIVGSGQSAAEVFHDLLRESGRHDYSLAWITRSPRFFQMENTKLTLELISPDYTEYFHDLPEARRQEILTQQNSLYKGINASLINQIYDLLDEKVHDGDNRYTLLTNSELRACRYDPLQERFQLDFQHLDCDRPFSHATDGLVLATGYSHEIPACINPIHDRIAWNADGSYRIGRNYAIDHEGSEIFVQNTGLLSHGVTNPDLGFCCYRNSQILRELTGTEHYRIETRTALQEFSPPADGVLKHRPARRAERGPTVAARPLMDIHRATL
What are the official names of this protein?
Alcaligin biosynthesis enzyme.
What is the protein family that this protein belongs to?
Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.
Protein: RHLB_PSEA6
Sequence: MQTTHLTETHFADLPINEQVVKALSAANFSHCTPIQALSLPPLLEGNDIAGQAQTGTGKTIAFLVATFHYLLSNPQPTKKQPRAIIMAPTRELAVQIFNDAELLSQHTGLSLGLIYGGEGYQSQREKLEEGVDIIIGTTGRIIDYYKQNIFSLAGIQVAVLDEADRMFDLGFIKDIRYLFNRMPKPTERLSMLFSATLSYRVQELAYEHMDNPTHVQVEPERKTGTRIKEELFYPSDEDKMALLLSLMEEEWPDKAIVFANTKHSCEKVADWLQADGHRVGLLSGDVPQNKRLKILEDFTSGKLDILVATDVAARGLHIPMVSHVFNYDLPDDAEDYVHRIGRTGRAGQSGSSISFACERYALNLPAIETYIEHAIPVTEYQADALLRDVTPPKPRHKKRMQNGRNPQKRQSSGSRNRRKP
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_SYNSC
Sequence: MPYRISRQAYAETYGPTTGDRIRLADTDLILEVEKDYTVYGDEVKFGGGKVIRDGMGQSQTPRAEGAVDTVITNALILDWWGIVKADVGLKDGRIVGIGKAGNPDTQEGVTIVVGPGTEAIAGEGHILTAGGIDTHIHFICPQQIETALASGVTTLMGGGTGPATGTNATTCTPGAFHIGRMLQAAEGLPVNLGFFGKGNASTPEALEEQVRAGACGLKLHEDWGTTPATIDACLSVADRMDVQVCIHTDTLNEAGFVEDTIAAIKGRTIHTFHTEGAGGGHAPDIIKICGEANVLPSSTNPTRPYTRNTLEEHLDMLMVCHHLDPKIPEDVAFAESRIRRETIAAEDILHDLGSFSIIASDSQAMGRVGEVITRTFQTAHKMKVQRGALPEDSARNDNHRLKRYIAKVTINPALAHGISSEVGSIETGKLADLVLWKPGFFGIRPELVVKGGSIVWAQMGDANASIPTPGPVHGRPMFGAFGKALAPSCLTFVSEAAMDADIQRQLGLERTCMAVRDTRSVGKSALKLNSALPKVSVDPQTYEVFADGELLTCEPAEVLPLAQRYLLL
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBA1_MOUSE
Sequence: MAARLIGFFLFQAVSWAYGAQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ
What is the function of this protein?
Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramides/GlcCers (such as beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine) into free ceramides (such as N-acylsphing-4-enine) and glucose (PubMed:24211208).  Plays a central role in the degradation of complex lipids and the turnover of cellular membranes (PubMed:27378698).  Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation (By similarity).  Catalyzes the glucosylation of cholesterol, through a transglucosylation reaction where glucose is transferred from GlcCer to cholesterol (PubMed:24211208).  GlcCer containing mono-unsaturated fatty acids (such as beta-D-glucosyl-N-(9Z-octadecenoyl)-sphing-4-enine) are preferred as glucose donors for cholesterol glucosylation when compared with GlcCer containing same chain length of saturated fatty acids (such as beta-D-glucosyl-N-octadecanoyl-sphing-4-enine) (By similarity).  Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl 3-beta-D-glucoside to ceramide (By similarity).  Can also hydrolyze cholesteryl 3-beta-D-glucoside producing glucose and cholesterol (By similarity).  Catalyzes the hydrolysis of galactosylceramides/GalCers (such as beta-D-galactosyl-(1<->1')-N-acylsphing-4-enine), as well as the transfer of galactose between GalCers and cholesterol in vitro, but with lower activity than with GlcCers (By similarity).  Contrary to GlcCer and GalCer, xylosylceramide/XylCer (such as beta-D-xyosyl-(1<->1')-N-acylsphing-4-enine) is not a good substrate for hydrolysis, however it is a good xylose donor for transxylosylation activity to form cholesteryl 3-beta-D-xyloside (By similarity).
What are the official names of this protein?
Lysosomal acid glucosylceramidase, Lysosomal acid GCase, Acid beta-glucosidase, Beta-glucocerebrosidase, Cholesterol glucosyltransferase, SGTase, Cholesteryl-beta-glucosidase, D-glucosyl-N-acylsphingosine glucohydrolase, Lysosomal cholesterol glycosyltransferase, Lysosomal galactosylceramidase, Lysosomal glycosylceramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 30 family.
Protein: CCME_ECO81
Sequence: MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: EX7S_DESVH
Sequence: MAGRKKAADFEQQLARLQEIVDALEGGDLPLEKSVALYKEGLGLARASREQLAKARNEIRLFTEGEVRDFDPEEGDDGDDR
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PG050_VACCC
Sequence: MSKILTFVKNKIIDLINNDQIKYSRVIMIEESDSLLPVDEVHANHGFDCVEMIDENISNENIEQYKTESFFTIN
What are the official names of this protein?
Protein OPG050, Protein F6.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG050 family.
Protein: LIVH_SALTI
Sequence: MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHGEVYMIGSYVSFMIIAALMMMGIDTSWLLVAAGFIGAIIIASAYGWSIERVAYRPVRNSKRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWIVGSSENFSASITTMQAVIWIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAVAGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGVAEALSSAYLSTEYKDVVSFALLILVLLVMPTGILGRPEVEKV
What is the function of this protein?
Part of the binding-protein-dependent transport system for branched-chain amino acids.  Probably responsible for the translocation of the substrates across the membrane (By similarity).
What are the official names of this protein?
High-affinity branched-chain amino acid transport system permease protein LivH, LIV-I protein H.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPIA_XANOM
Sequence: MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGHIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGNLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHNLQITDPVALERSLNQIPGVVCVGLFARRPADVVIVGGEPPRVL
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.