PharMolix/UniProtQA huggingface dataset:
Protein: RPOC_BACVZ
Sequence: MLDVNNFEYMNIGLASPDKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECHCGKYKRVRYKGVVCDRCGVEVTRAKVRRERMGHIELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEVIYFASYVVTDPANTPLEKKQLLSEKEYRAYLDKYGNKFQASMGAEAINKLLQDIDLVKEVDMLKEELKTSQGQRRTRAIKRLEVLEAFRNSGNKPSWMILDVLPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPSIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPHLKMYQCGLPKEMALELFKPFVMKELVEKGLAHNIKSAKRKIERVQPEVWDVLESVIKEHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVCTAYNADFDGDQMAVHVPLSAEAQAEARILMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERAGAVGEGMVFKNTDEALLAYQNGYVHLHTRVAVAANSLKNVTFTEEQRSKLLITTVGKLVFNEILPESFPYMNEPTKSNIEEKTPDRFFLDKGADVKAVIAEQPINAPFKKGILGKIIAEIFKRFHITETSKMLDRMKNLGFRYSTKAGITVGVSDIVVLDDKQEILEEAQSKVDNVLKQFRRGLITEEERYERVISIWSSAKDVIQGKLMKSLDEVNPIYMMSDSGARGNASNFTQLAGMRGLMANPAGRIIELPIKSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIIRETDCGTDRGILAKPLKEGTEIIERLEERLIGRFARKQIKHPETGAVLINENELIDEDKALEIVEAGIEEVWIRSAFTCNTPHGVCKRCYGRNLATGTDVEVGEAVGIIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRIQELFEARNPKGQATISEIDGTIAEINEVRDKQQEIVVQGAVETRSYTAPYNSRLKVAEGDQITRGQVLTEGSIDPKELLKVTDLTTVQEYLLHEVQKVYRMQGVEIGDKHVEVMVRQMLRKVRVIDAGDTDVLPGTLLDIHQFTEANKKVLLEGNRPATGRPVLLGITKASLETDSFLSAASFQETTRVLTDAAIKGKRDELLGLKENVIIGKLVPAGTGMMNYRKVKPVSNVQPTEDMVPAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: ATPJ_YEAST
Sequence: MSTVNVLRYSALGLGLFFGFRNDMILKCNAKKKEEQAQYEEKLKLVEEAKKEYAKLHPVVTPKDVPANASFNLEDPNIDFERVILNAVESLKEAST
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane.
What are the official names of this protein?
ATP synthase subunit e, mitochondrial, ATPase subunit e, Translocase of the inner membrane protein 11.
What is the protein family that this protein belongs to?
Belongs to the ATPase e subunit family.
What are the subcellular locations of this protein?
Mitochondrion. Mitochondrion inner membrane.
Protein: BEX2_HUMAN
Sequence: MESKEERALNNLIVENVNQENDEKDEKEQVANKGEPLALPLNVSEYCVPRGNRRRFRVRQPILQYRWDIMHRLGEPQARMREENMERIGEEVRQLMEKLREKQLSHSLRAVSTDPPHHDHHDEFCLMP
What is the function of this protein?
Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer.  Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA.  Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A.  Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity.
What are the official names of this protein?
Protein BEX2, Brain-expressed X-linked protein 2, hBex2.
What is the protein family that this protein belongs to?
Belongs to the BEX family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: NRAM1_BOVIN
Sequence: MSGDTGPPKQGGTRYGSISSPPSPEPQQAPPGGTYLSEKIPIPDTESGTFSLRKLWAFTGPGFLMSIAFLDPGNIESDLQAGAVAGFKLLWVLLWATVLGLLCQRLAARLGVVTGKDLGEVCHLYYPKVPRILLWLTIELAIVGSDMQEVIGTAIAFSLLSAGRIPLWGGVLITVVDTFFFLFLDNYGLRKLEAFFGFLITIMALTFGYEYVVAQPAQGALLQGLFLPSCPGCGQPELLQAVGIIGAIIMPHNIYLHSSLVKSREVDRSRRADIREANMYFLIEATIALSVSFLINLFVMAVFGQAFYKQTNQAAFNICADSSLHDYAPIFPRNNLTVAVDIYQGGVILGCLFGPPALYIWAVGLLAAGQSSTMTGTYAGQFVMEGFLKLRWSRFARVLLTRSCAILPTVLLAVFRDLRDLSGLNDLLNVLQSLLLPFAVLPILTFTSMPALMQEFANGLVSKVITSSIMVLVCAVNLYFVISYLPSLPHPAYFSLVALLAAAYLGLTTYLVWTCLITQGATLLAHSSHQRFLYGLPEEDQEKGRTSG
What is the function of this protein?
Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens.  Macrophage-specific membrane transport function.  Controls natural resistance to infection with intracellular parasites.  Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes (By similarity).
What are the official names of this protein?
Natural resistance-associated macrophage protein 1, NRAMP 1, Solute carrier family 11 member 1.
What is the protein family that this protein belongs to?
Belongs to the NRAMP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: VME1_IBVD1
Sequence: MSNETNCTLDFEQSVELFKEYNLFITAFLLFLTIILQYGYATRSKFIYILKMIVLWCFWPLNIAVGVISCIYPPNTGGLVAAIILTVFACLSFVGYWIQSIRLFKRCRSWWSFNPESNAVGSILLTNGQQCNFAIESVPMVLSPIIKNGVLYCEGQWLAKCEPDHLPKDIFVCTPDRRNIYRMVQKYIGDQSGNKKRFATFVYAKQSVDTGELESVATGGSSLYT
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the gammacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: ATPE_PROMA
Sequence: MSLTLRVLAPDKSVFDDTVEEVILPSTTGLLGILPGHISMVTAIDIGVLKLRSSNGNWDSIALMGGFAEVESDDVTVLVNAAELGKSIDKATAEKEFEQAKAALNKLEDQAGNSADKLKAKESLNKARARSQAVGE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: ADD_ALIF1
Sequence: MIIKQLPLTDLHRHLDGNIRIETILDLGQKFGLDLPAYDIEALRPHVQIVEAEPSLVAFLSKLDWGVAVLGDLDACRRVAYENVQDAMNAQIDYAELRFSPYYMAMKHNLPIAGVVEAVVDGVEAGCRDFGIKANLIGIMSRTFGQDACQQELDGLLTQKHKLVAIDLAGDELGQPGDLFVNHFKQVKDADLRVTVHAGEAAGAASMWQAINELGAVRIGHGVKAIEDPKLMEYLAKNNIGIESCLTSNIQTSTVASFESHPIKTFLDYGVKVCLNTDDPAVEGIELPHEYEVAAPKVGLTPEQLKQIQINGLDLAFLSDSEKQALREMAAKR
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: NQO7_PARDE
Sequence: MEYLLQEYLPILVFLGMASALAIVLILAAAVIAVRNPDPEKVSAYECGFNAFDDARMKFDVRFYLVSILFIIFDLEVAFLFPWAVSFASLSDVAFWGLMVFLAVLTVGFAYEWKKGALEWA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit 7, NADH dehydrogenase I subunit 7, NDH-1 subunit 7.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EPO_HORSE
Sequence: MGVRECPALLLLLSLLLPPLGLPALGAPPRLICDSRVLERYILEAREAENVTMGCAEGCSFGENVTVPDTKVNFYSWKRMEVEQQAVEVWQGLALLSEAILQGQALLANSSQPSETLRLHVDKAVSSLRSLTSLLRALGAQKEAISPPDAASAAPLRTFAVDTLCKLFRIYSNFLRGKLKLYTGEACRRGDR
What is the function of this protein?
Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass.  Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
What are the official names of this protein?
Erythropoietin.
What is the protein family that this protein belongs to?
Belongs to the EPO/TPO family.
What are the subcellular locations of this protein?
Secreted.
Protein: RSMA_BURM7
Sequence: MSNSRQHQGHFARKRFGQNFLVDHGVIDAIVAAIRPERGERMVEIGPGLGALTGPVIARLATPGSPLHAVELDRDLIGRLEQRFGELLELHAGDALTFDFGSIARPGDEPSLRIIGNLPYNISSPLLFHLMSFAPVVIDQHFMLQNEVVERMVAEPGTKAFSRLSVMLQYRYVMDKLIDVPPESFQPPPKVDSAIVRMIPHAPHELPAVDPAVLGEVVTAAFSQRRKMLRNTLGGYRDLVDFDALGFDLARRAEDIGVDEYVRVAQAVASARASG
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRD_MOUSE
Sequence: MAWRQLRKRALDAAIILGGGGLLFTSYLTATGDDHFYAEYLMPALQRLLDPESAHRLAVRVISLGLLPRATFQDSNMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKLGFGFVEVGSVTPQPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSAVEHRLRARQQKQTQLTTDGLPLGINLGKNKTSVDAAADYVEGVRILGPLADYLVVNVSSPNTAGLRSLQGKTELRRLLSKVLQERDALKGPQKPAVLVKIAPDLTAQDKEDIASVARELGIDGLIITNTTVSRPVGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGTIPIIGVGGVSSGQDALEKIQAGASLVQLYTALTFLGPPVVARVKRELEALLKERGFNTVTDAIGVDHRR
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.  Required for UMP biosynthesis via de novo pathway.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), mitochondrial, DHOdehase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: MUTS_ROSS1
Sequence: MTPAERRAFERQLQQEFPGLELHAWYRQYRSLKAAHPDAILLYRLGDFYETFDDDAKLVADLLEVTLTYKEFASQKGRDQKQRCPMAGIPYHAVEGYVARLVGAGYRVAIAEQITETPSSRTDTRPRSIFAAGIEQTSLTGSNRMVERKVVRVITPGTIIESGMIPAERNNYLAALIADHGRIGLAYADLSTGEFAAVEFSGERAAQQAQGELTRLNAAEILVPDRADLRLPGLEPSSARLEQDLEFLTREERELLLPGERVARRVERENNARWAHGRVTAWPERRWDLRNAHDTLLHQFGVRSLAGFGLEDRPLAIRAAGAIVQYARETQQGVVANLRSIRAYTPGDAMFLDPQTQRNLELLEGASGTTRGSLIGVLDQTRTPMGARLLRRWVSQPLCDLTRLHARHDAVERFVTDAILRASVRETLRRVGDMERVVNRIIQGVGVATPRDMARLRDALRALPELVAALGDWTPPPGEIDLTGVRTLPPSAATDPVSLTENGNERIEPNQTSAVSLRAQREARRRVSARYADEDLFGEEEQNAPPVGSSNHAVGTQPSADDEASPVTAFVDDQATETLALDPCADMLAFLETAIDDEPPALLGASNYLRAGENGEPPRRVIRPGFEPEIDQVVAASRDAQRWISELEPKERERTGIKSLRVDYNRVFGYYIEVPKTYADQVPKHYIRKQTLTTGERYFTDELKRYEEIVEQAQQRLIDLERRAFARICDVVTGAGARLLRTARMIATIDVFAALAEAAVRGRYVRPELYDDTRLRIVGGRHPVVEQTLDETFVPNDIEMDTETRQICLITGPNMSGKSTVLRQVALIALMAQIGSFVPADAAEIGLVDRIFTRIGAQDDIATGRSTFMVEMTETAALLAQSTRRSLIILDEVGRGTSTYDGMAIAQAVIEYIHNEPRLGCRTLFATHYHELTDLERTLPRLKNYHMAATEQDGRVVFLHELRPGGADRSYGIHVAELAGIPQSVIRRASELLAELERRAPRSAPPTVPARGDDRRSAGRASSSGAGAARGEQGRTLPDGQLSLFDLAPGPVIEMLRRIDINQLTPLEALNKLHELQKLARAGGG
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: PAP1_BRACM
Sequence: MATTVPLFSQFTCKTPITSSSTSSFQSKSPILLPINPINRRIAVHRHDFKVRASDVNDEWGPDSKGRGGDVDDEWGPEIGLNSSVAEKVAEEAIESAEETERLKRVLAGSLYGTDRGLSASSETRAEISELITQLESKNPNPAPNEALFLLNGKWILVYTSFVGLFPLLSRRISPLVKVDEISQTIDSDSFTVHNSVRFASPLATTSLSTNAKFEVRSPKRVQVKFEQGVIGTPQLTDSIEIPEFVEVLGQKIDLNPIKGLLTSVQDTASSVARTISSQPPLKFSLPGDSAQSWLLTTYLDKDLRISRGDGGSVFVLIREGSSLLNP
What is the function of this protein?
May modulate the action of carotenoids.
What are the official names of this protein?
Plastid lipid-associated protein 1, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the PAP/fibrillin family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: AROE_HALOH
Sequence: MFDNSTQVVGLMGYPLGHSMSPAMHNRAYKDLGINYVYLPLEIKPDFLKEGIEGLRAFNFRGVNVTIPYKEKVIPYLDEIDRLAGEIGAVNTIVNNGGKLKGYNTDALGFKKMLEDDCSFEIKGTKAVIIGAGGASRAVGAVLAREGASEIFLLNRTLKKAAKLVGIWNKTYPGIKTVALPLDEDKYLPVVKRCDVIIDTTPVGMAPGIKGGPVIAKEAITRDTLVVDLVYNPPETTLIKAGRQVGARTMNGFPMLIYQAAYAFKLWTGIKPELFIKPVREAISPDFFA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: G6PI_STRPQ
Sequence: MSHITFDYSKVLESFAGQHEIDFLQGQVTEADKLLREGTGPGSDFLGWLDLPENYDEEEFARILTAAEKIKSDSEVLVVIGIGGSYLGAKAAIDFLNHHFANLQTAKERKAPQILYAGNSISSTYLADLVEYVQDKEFSVNVISKSGTTTEPAIAFRVFKELLVKKYGQEEASKRIYATTDKVKGAVKVEADANNWETFVVPDNVGGRFSVLTAVGLLPIAASGADITALMEGANAARKDLSSDKISENIAYQYAAVRNLLYRKGYITEILANYEPSLQYFGEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDNPRKNVIIPELAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFVTLPAQDEFTLGYTIYFFELAIAVSGYMNAVNPFDQPGVEAYKRNMFALLGKPGFEALSAELNARL
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_PHYAS
Sequence: MIIEIVTIFPLFFKSFCDNSIIKRALNQQKVQIKIHDLRKYSVNKHQQVDDCVYGGGVGMLLSFPPFFDCLQEIKTPQSKVILLSPQGKIFDQVQANNYASNTPHLIILCGNYEGVDARILKYVDQEISIGDYVLTGGEIAATVVVDAIVRLIPGVIKHESAFSDSHQQGLLKFPQYTRPQIYQNQEVPSVLLSGNHAQIENWRQKESLKITLQKRPDLLINKKLSSKEKVILEEIKQELKNNS
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DIF1_LACTC
Sequence: MTESPQKRHLGQGIERQNEQYACQGALSTIGMRIRQSVDRGYQVSGAAPAPAARTAASCVQDNSELTIPDYKRVPMPSSKQAPMLVNSRTVSSSSSLEMWENQLDERLEHIDNDIMRNKRAFEQVEDW
What is the function of this protein?
Mediates the nuclear localization of the ribonucleotide reductase.
What are the official names of this protein?
Damage-regulated import facilitator 1.
What is the protein family that this protein belongs to?
Belongs to the DIF1/spd1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: GAK24_HUMAN
Sequence: MGQTKSKIKSKYASYLSFIKILLKRGGVKVSTKNLIKLFQIIEQFCPWFPEQGTLDLKDWKRIGKELKQAGRKGNIIPLTVWNDWAIIKAALEPFQTEEDSVSVSDAPGSCLIDCNEKTRKKSQKETESLHCEYVAEPVMAQSTQNVDYNQLQEVIYPETLKLEGKGPELVGPSESKPRGTSPLPAGQVPVTLQPQKQVKENKTQPPVAYQYWPPAELQYRPPPESQYGYPGMPPAPQGRAPYPQPPTRRLNPTAPPSRQGSELHEIIDKSRKEGDTEAWQFPVTLEPMPPGEGAQEGEPPTVEARYKSFSIKMLKDMKEGVKQYGPNSPYMRTLLDSIAYGHRLIPYDWEILAKSSLSPSQFLQFKTWWIDGVQEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSACPSFNTVRQGSKEPYPDFVARLQDVAQKSIADEKARKVIVELMAYENANPECQSAIKPLKGKVPAGSDVISEYVKACDGIGGAMHKAMLMAQAITGVVLGGQVRTFGGKCYNCGQIGHLKKNCPVLNKQNITIQATTTGREPPDLCPRCKKGKHWASQCRSKFDKNGQPLSGNEQRGQPQAPQQTGAFPIQPFVPQGFQGQQPPLSQVFQGISQLPQYNNCPLPQAAVQQ
What is the function of this protein?
The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle.  During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell.  Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA.  Endogenous Gag proteins may have kept, lost or modified their original function during evolution.
What are the official names of this protein?
Endogenous retrovirus group K member 24 Gag polyprotein, HERV-K101 Gag protein, HERV-K_22q11.21 provirus ancestral Gag polyprotein, Gag polyprotein.
What is the protein family that this protein belongs to?
Belongs to the beta type-B retroviral Gag protein family. HERV class-II K(HML-2) gag subfamily.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Cytoplasmic membrane (in a transfection system).
Protein: YDEQ_BACSU
Sequence: MDHMKTLVLVVHPNIESSRINKKWKEAVLSEPDVTVHDLYEKYRDQPIDVEFEQQQLLAHDRIVFQFPLYWYSSPPLLKQWFDEVFTFGWAHGPGGNKLKGKEWVTAMSIGSPEHSYQAGGYNLFSISELTKPFQASAHLVGMTYLPSFAEYRANTISDQEIAESANRYVKHITNIELNPKVRLQRYLKQLESVDLT
What are the official names of this protein?
Uncharacterized NAD(P)H oxidoreductase YdeQ.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)H dehydrogenase (quinone) family.
Protein: RS21_ACTP7
Sequence: MPVIKVRENESFDVALRRFKRSCEKAGLLAEVRAREFYEKPTTIRKREKASLAKRHAKRNARENARNTRLY
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: QRFPR_HUMAN
Sequence: MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSGH
What is the function of this protein?
Receptor for the orexigenic neuropeptide QRFP.  The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels.
What are the official names of this protein?
Pyroglutamylated RF-amide peptide receptor, AQ27, G-protein coupled receptor 103, Orexigenic neuropeptide QRFP receptor, SP9155.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: TUSA_PSEAB
Sequence: MTHSVDAILDATGLNCPEPVMMLHNKVRDLAPGGLLKVIATDPSTRRDIPKFCVFLGHELVEQQEEAGTYLYWIRKKAD
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_DEHM1
Sequence: MKILGIESSCDETAAAVVADGVNILSNRVSSQIDIHSRYGGVVPEVASRQHLLSILPVISDALKEARTGFDEISAIAVTNGPGLAGSLIVGVNAAKAIAAARGIPLVAVNHLHGHIYANWLSGRIPEFPCLCLTVSGGHTDLVLMKGHGQYQLLGRTRDDAAGEAFDKAARILGLSYPGGPAIDRASQDGEAVLDLPRSWIPGSHDFSFSGLKTALLRLVENGEVCSVNDAAASFQKAVVDVLVTKTLNCAHEYNVKQILLAGGVAANNLLRKQLSEQSPLPVSIPPIGLCTDNAAVIASCGYFRFISGGQDRLDMDVLPALSVVS
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRG_STAA8
Sequence: MTKFIFVTGGVVSSLGKGITASSLGRLLKDRGLNVTIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTAGKVYSHVLKKERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFIEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMTQDLKDKIALFCDINKESVIECRDADSLYEIPLQLSQQNMDDIVIKRLQLNAKYETQLDEWKQLLDIVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFAKDIDIRWIDSSEVTDENAAEYLADVDGILVPGGFGFRASEGKISAIKYARENNVPFFGICLGMQLATVEFSRNVLGLEGAHSAELDPATPYPIIDLLPEQKDIEDLGGTLRLGLYSCSIKEGTLAQDVYGKAEIEERHRHRYEFNNDYREQLEANGMVISGTSPDGRLVEMVEIPTNDFFIACQFHPEFLSRPNRPHPIFKSFIEASLKYQQNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: COBT_SALPC
Sequence: MQTLHALLRDIPAPDAEAMARAQQHIDGLLKPPGSLGRLETLAVQLAGMPGLNGTPQVGEKAVLVMCADHGVWDEGVAVSPKIVTAIQAANMTQGTTGVCVLAAQAGAKVHVIDVGIDAEPIPGVVNMRVARGCGNIAVGPAMSRSQAEALLLEVSRYTCDLAQRGVTLFGVGELGMANTTPAAAMVSVFTGSDAKEVVGIGANLPPSRIDNKVDVVRRAIAINQPNPRDGIDVLSKVGGFDLVGMTGVMLGAARCGLPVLLDGFLSYSAALAACQIAPAVRPYLIPSHFSAEKGARIALAHLSMEPYLHMAMRLGEGSGAALAMPIVEAACAMFHNMGELAASNIVLPEGNANAT
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: CYC_NEUCR
Sequence: MGFSAGDSKKGANLFKTRCAQCHTLEEGGGNKIGPALHGLFGRKTGSVDGYAYTDANKQKGITWDENTLFEYLENPKKYIPGTKMAFGGLKKDKDRNDIITFMKEATA
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.