PharMolix/UniProtQA huggingface dataset:
Protein: PNP_BORHD
Sequence: MRKILRLKVGREDLILETGLLAKQANGAVLATYGGSTVLATVCCSDSVRENLDFVPLSVEYNEKYYAAGKIPGGFIKREGKPKDKEVLVSRLIDRPMRPLFDKRFGREIQVVPTTLSTDQMNPPDIVGMNAAFAAVFLSDIPFNGPIAAVRLAYLNNEFIVNPSFDEIQDSILDIVVAGSLDGITMVEGGANEVSEEVLLSAIDKAYEYIKQICNLQKEFVSIIGEREKLPLAYEEGVFEFKDELKNLIYSELKDACFVKGKLNRDKAIKLVKQKAYEHFSSISQVNEDNEFLFYKAFDDFEREIVRKSILENNLRTDGRTSTQIRDIVAEVDLLKRTHGSSLFTRGETQALAVTTLGTSIDEQIMDDIDGDKRLNFMLHYNFPPFSVGETGRLMTGRREVGHGHLAQRSLEAMLPKKDDFPYTIRVVSEILESNGSSSMATVCSGSMSLMAAGVPVKEQVAGIAMGLISDGDKYVVLSDILGEEDHLGDMDFKVAGTKNGITGFQMDIKISNVTKQLMKDALEQARIGRMHILSIMDSVISRSRDDISVNAPKIVQLQIDIDKISLVIGSTGKTVKAITDEFEVRVQIEQDGRITLFGTDSLKMQKAKAKIESIVREPKIGEIYDGIVKKINSFGAFIELTPIKEGFLSNRARSRDDRYGDMRHSRYGSGRHSRYGRDNRNTFGMNPPRLEEGQIVKVKISDIDKFGKIELELVRD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZMAT1_XENTR
Sequence: MAAESAIIPQLAESITPSSPAATCSGPMAGGDTSSNAHTSIPCQQDIVLDEQTKRELFTDTFCKVCNAVLQFESHRISHYEGKKHAQKVRLYFLKNELEEMALKTQRTDRVEFHVDGEVAQGKHKFCGLCNMVFSSPVVAQTHYVGKVHAKKMRQLAGEQVEWTPQTDQDFAAAAATSPVDSQTEIADSPAVEPTCDRRCEQEGSAEQQSCPDYEIDLNDPNKYCKLCCASFNKALVAQQHYSGKKHARNQARKKMMEEMEGTGVADSEVSDGRYVCPICNITLTSIEMYQSHMQGNKHQIKESMVANLMKTSKKNYDSFQDELADYIKVQKARGLVPKTQFRQEKDQYDSCDYEEEEEQEPEPGLLHGHINSKTNAPYKYLDRHPVPYPAHNPSHPTDQRVPPWAAHWEQASRPPKGHHLDLHKAKHISRSPTSQDSSDNSSGSSSDESSGSYKKDKRRKRKHHRESRLRGSGRIRRGDENSEKRKRKGEDADSGKEDNKHDRGKTSGGDKDKHRREKKKKEEQSKKHKKLKKEGEQRTEEEMLWDESILGF
What are the official names of this protein?
Zinc finger matrin-type protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: ECOT_ECO7I
Sequence: MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRIWKAEEKIDNAVVR
What is the function of this protein?
General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases.
What are the official names of this protein?
Ecotin.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I11 (ecotin) family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NANO2_HUMAN
Sequence: MQLPPFDMWKDYFNLSQVVWALIASRGQRLETQEIEEPSPGPPLGQDQGLGAPGANGGLGTLCNFCKHNGESRHVYSSHQLKTPDGVVVCPILRHYVCPVCGATGDQAHTLKYCPLNGGQQSLYRRSGRNSAGRRVKR
What is the function of this protein?
Plays a key role in the sexual differentiation of germ cells by promoting the male fate but suppressing the female fate.  Represses the female fate pathways by suppressing meiosis, which in turn results in the promotion of the male fate.  Maintains the suppression of meiosis by preventing STRA8 expression, which is required for premeiotic DNA replication, after CYP26B1 is decreased.  Regulates the localization of the CCR4-NOT deadenylation complex to P-bodies and plays a role in recruiting the complex to trigger the degradation of mRNAs involved in meiosis.  Required for the maintenance of the spermatogonial stem cell population.  Not essential for the assembly of P-bodies but is required for the maintenance of their normal state (By similarity).
What are the official names of this protein?
Nanos homolog 2, NOS-2.
What is the protein family that this protein belongs to?
Belongs to the nanos family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Cytoplasm, perinuclear region. Note=Localizes at P-bodies during gonocyte development (By similarity). More abundant in perinuclear region of the cytoplasm of the germ cells of the adult testis.
Protein: ARCR_STAA1
Sequence: MTENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYTKGQVIYFSPQESSNIYFLIEGNIIREHYNQNGDVYRYFNKEQVLFPISNLFHPKEVNELCTALTDCTVLGLPRELMAFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDRIIKLLCHLCQTVGYDQDEFYEIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKDHKNWLVSKHLFNDVCV
What is the function of this protein?
Positively regulates the expression of the arcABDCR operon under anaerobic conditions, thus playing an essential role in arginine catabolism.  May also control the expression of genes encoding proteins which are involved in anaerobic metabolism.  Can bind cyclic AMP (By similarity).
What are the official names of this protein?
HTH-type transcriptional regulator ArcR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPME1_KLULA
Sequence: MSGNLQREALLKEFENAGKMIHAFDTAPEGNGEEDTITELPVVKNPGLGVSSETKAENMEDTGFPRWTEFFAKNETVSLPNRNFTFNTYFQVPEVNSSDLSSIPIFLAHHGAGSTGLTFAPLAKTLKEDLGTNFGFFSFDARGHGETKPLDPTDVTYYLNDFVTDFVELIVWFYENYLKACKQSKLSLILVGHSLGGSVCANLYEHLPEYIKRHTTGLAMLDIVEEMAKFVLTKVDHFLSVTPNVFGSAKEAVDWYQSHNYSKLKESAEISVPALFHKAKSGKVVRITNLASFKPYWDSWFDGLSAKFVSLPTSKLLILAGNDNLDKELIVGQMQGKYQLIVFQDSGHFIQEDVPKKAAISLVDFWKRSDNRNVTIKTNWGSSQNKTLEGKKTVE
What is the function of this protein?
Demethylates proteins that have been reversibly carboxymethylated.  Demethylates the phosphatase PP2A catalytic subunit (By similarity).
What are the official names of this protein?
Protein phosphatase methylesterase 1, PME-1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: TRUA_VARPS
Sequence: MRLALGIRYNGQAYEGWQSQRSGRTVQDKLEAALAKFAAQPIGTLCAGRTDAGVHALMQVVHFDTTVEREPFSWMRGTNRFLPDDIAVQWAQPVPDEFHCRASALARRYLYVLSQSPVRPSLDSGRVGWSMHPLDGDAMRAAAALLVGKHDFSSFRASACQARSPVKDLRRIEITRVGSGDRCRWHFEFEADAFLHHMIRNLMGCLVRIGRGDERPEWITEVLEARSRKVAAPTFSANGLYFLGPLYDAKWGLPAEATLQAGGAPYDGPP
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: FABA_SALTY
Sequence: MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMTETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTARKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTAHDLKVGLFQDTSAF
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CY24A_HUMAN
Sequence: MGQIEWAMWANEQALASGLILITGGIVATAGRFTQWYFGAYSIVAGVFVCLLEYPRGKRKKGSTMERWGQKYMTAVVKLFGPFTRNYYVRAVLHLLLSVPAGFLLATILGTACLAIASGIYLLAAVRGEQWTPIEPKPRERPQIGGTIKQPPSNPPPRPPAEARKKPSEEEAAVAAGGPPGGPQVNPIPVTDEVV
What is the function of this protein?
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide.  Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
What are the official names of this protein?
Cytochrome b-245 light chain, Cytochrome b(558) alpha chain, Cytochrome b558 subunit alpha, Neutrophil cytochrome b 22 kDa polypeptide, Superoxide-generating NADPH oxidase light chain subunit, p22 phagocyte B-cytochrome, p22-phox, p22phox.
What is the protein family that this protein belongs to?
Belongs to the p22phox family.
Protein: SYI_YERP3
Sequence: MSDYKNTLNLPETGFPMRGDLAKREPDMLKRWYEQDLYGIIRAAKKGKKTFILHDGPPYANGNIHIGHSVNKILKDIIVKSKGMAGYDSPYIPGWDCHGLPIELKVEQLIGKPGEKVSAAEFRTACRKYAAEQVEGQKKDFIRLGVLGDWDHPYLTMDFKTEANIIRALSKIIDNGHLHKGAKPVHWCTDCGSSLAEAEVEYYDKTSQSIDVRFNAVDTATVAAKFGVSVVNGPISLVIWTTTPWTLPANRAISLNAEYLYQLVQVEGECLILAADLVESVMKRAGITQWAVLGSCTGSDLELLRFTHPFMGFDVPAILGEHVTLDAGTGAVHTAPGHGPDDFVIGQKYGLEVANPVGPNGCYLAGTYPTLDGLFVFKANDVVVELLREKGALLHVEKLLHSYPCCWRHKTPIIFRATPQWFISMDQKGLRKQSLQEIKDVQWIPDWGQARIETMVANRPDWCISRQRTWGVPMSLFVHKETEQLHPRSIELMEEVAKRVEQDGIQAWWDLDPAEILGADAADYVKVPDTLDVWFDSGSTHSSVVDARPEFGGHSPDMYLEGSDQHRGWFMSSLMIATAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTISPQDVMNKLGGDILRLWVASTDYTGEIAVSDEILKRSADSYRRIRNTARFLLANLNGFDPAQHQVKPEEMVVVDRWAVGRAQAAQAEIMEAYENYDFHLVVQRLMQFCSVEMGSFYLDIIKDRQYTAKGDGIARRSCQTALFHIAEALVRWMAPIMSFTADEIWNHLPGERQQYVFTEEWYDGLFGLAGNESMNDTFWAELLKVRGEVNKVLEQARSDKRIGGSLEAAVTLYAEPELAARLNSLQDELRFVLLTSAAKVAAYADAGNDAQQSELIAGLKITFNKADGEKCPRCWHYTQDVGLVAEHAELCGRCVTNVAGDGEERKFA
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMA_ECO8A
Sequence: MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIHC_ECO45
Sequence: MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNVDIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRQPLGIPAFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTPNAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAWLVRPELFTLKPCFVAVETQGEFTSGTTVVDIDGCLGKPANVQVALDLDVKGFQQWVAEVLALAL
What is the function of this protein?
Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
What are the official names of this protein?
Non-specific ribonucleoside hydrolase RihC, Purine/pyrimidine ribonucleoside hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihC subfamily.
Protein: NCAP_INBAC
Sequence: MSNMDIDGINTGTIDKTPEEITSGTSGATRPIIKPATLAPPSNKRTRNPSPERAATSSEADVGRRTQKKQTPTEIKKSVYNMVVKLGEFYNQMMVKAGLNDDMERNLIQNAHAAERILLAATDDKKTEFQKKKNARDVKEGKEEIDHNKTGGTFYKMVRDDKTIYFSPIRITFLKEEVKTMYKTTMGSDGFSGLNHIMIGHSQMNDVCFQRSKALKRVGLDPSLISTFAGSTLPRRSGATGVAIKGGGTLVAEAIRFIGRAMADRGLLRDIRAKTAYEKILLNLKNKCSAPQQKALVDQVIGSRNPGIADIEDLTLLARSMVVVRPSVASKVVLPISINAKIPQLGFNVEEYSMVGYEAMALYNMATPVSILRMGDDAKDKSQLFFMSCFGAAYEDQRVLSALTGTEFKHRSALKCKGFHVPAKEQVEGMGAALMSIKLQFWAPMTRSGGNEVGGDGGSGQISCSPVFAVERPIALSKQAVRRMLSMNIEGRDADVKGNLLKMMNDSMTKKTNGNAFIGKKMFQISDKNKTNPIEIPIKQTIPNFFFGRDTAEDYDDLDY
What is the function of this protein?
Encapsidates the negative strand viral RNA, protecting it from nucleases.  The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication.  The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex.  NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway.  Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins.  It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export.  M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals.  Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein.  Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses nucleoprotein family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: RBFA_CLOBJ
Sequence: MAKYRAGRINEEVKKEVSNIIHNDIKDPRLSAMVSVTDVNVTKDLKYAKVYVSIFGNEKAKEESLEALKSSVGFIRKEVGRRVKLRNTPEVIIEVDNSIERGMHIDELLHSIKENESNDN
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACD11_MOUSE
Sequence: METDVTSDTVEVLPQHKFDLRSLEAYLNQHLPGFGSDSRAVLTVTQYRSGQSNPTFFLQKGSQAYVLRKKPPGSLLPKAHKIDREFKIQKALFSIGFPVAKPLLYCRDASVIGTEFYVMEHVQGRIFRDFSIPGVSSAERAAIYVSVAETLAWLHSLDIRSLKLDKYGTGVGYCKRQVSTWTKQYQASAHQSIPAMDQLSTWLMKNLPDSDSEECLVHGDFKLDNIVFHPKECRVIAVLDWELSTFGHPLTDLAHLSLFYYWPRTLPMINRGSHIPENTGIPLMEELISIYCHRRGIDPNLPNWNFFMALSFFKLAGISQGVYRRYLMGNNSSEDSFLTANTVQPLAETGLQLSKRTLRTTPPQADAKSQLFAQSRRGQEVLTRVKQFMKQHVFPAEKEVAEYYAQSGNSAEKWGHPLVIEKLKEMAKAEGLWNLFLPAVSGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHLYGSEQQKKQWLEPLLRGDITSVFCMTEPNVSSSDATNIECTIQRDGGGYIVNGKKWWSSGAGNPKCKIAIVLGRTESPSASRHRQHSMILVPMDTPGVELIRPLSVFGYMDNMHGGHWEVHFNHVRVPASNLILGEGRGFEISQGRLGPGRIHHCMRTVGLAERILQIMCDRAVQREAFKKKLYEHEVVAHWIAKSRIAIEEIRLLTLKAAHSIDTLGSASARKEIAMIKVAAPKAVCKIADWAIQVHGGAGVSQDYPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQARRLTARM
What is the function of this protein?
Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA.  Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain.
What are the official names of this protein?
Acyl-CoA dehydrogenase family member 11, ACAD-11.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Peroxisome. Mitochondrion membrane.
Protein: I329L_ASFK5
Sequence: MLRVFIFFVFLGSGLAGKVKSPITCKYFISKNNTWYKYNVTILNDTIILPAYNTIPTNATGISCTCHDIDYLQKNNISIRYNTSILKTFQDIRIIRCGMKNISEIAAGFSKELKFLDLRYNDLQFIEYNILRKLIRSNTPTYLYYNNLMCGKRNCPLYYFLLKQEQTYLKLLPQFFLRRISFSNNHTYLYHFLSCGNKPGHEFLEYQTKFCRTKFPEINITVNQLIAKKNTERYKNCYPFVLVSIICSCISSLFLLICLLRTICKKYSCTKQGKTTHSYIPLIPSYTFSLKKHRHPETAVVEDHASTANSPIVYIPTTEEKKVSCSRRK
What is the function of this protein?
Viral TLR3 homolog that probably prevents TLR3 dimerization and subsequent induction of IFN (By similarity).  Inhibits dsRNA-stimulated activation of NF-kB and IRF3 (By similarity).
What are the official names of this protein?
Transmembrane protein I329L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus I329L family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein.
Protein: OSW5_KLULA
Sequence: MTPWSLPQFAFHLVTFLSIAFIASIFVLPFLTFSFVLSSATVGLSFASRTSFEIGLFFYDRFVILLQGQLRGMIDQLPSNQPAKEEKKVKAQQQGDELFTQQEQAAPSQTLGSTIPLQSIEESLLDST
What is the function of this protein?
Involved in spore wall assembly.
What are the official names of this protein?
Outer spore wall protein 5.
What is the protein family that this protein belongs to?
Belongs to the OSW5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MNMC_ACISJ
Sequence: MSEPIEWLEDGTPYSPRFSDRYHSEHGGLEQARGTFLAGCGLPQAWQNQPQWRVLETGFGLGLNFLVTWAAWRADPHRPQRLHFVSCEAWPVSAADLLRAAPIDSTLQSLAQQLAAQYWGLLPGVHRLSFDGGQVLLTLYIGDAQALLRQQQPTADSVYLDGFDPQHNPQMWDIHTLKAVARCCRRGTRLATWTVARGVRDGLVQCGFEVQKVPGVRPKRDNLQATYAPRWEPRAGQPVLPDATVAAPARCLVVGAGLAGAAVAASLAHRGWQVQVLDRADHPAAGASGLPAGVFAPNVSQDDNLISRLSRAGVRITLNTLAQLPAETRGTDWSACGTLEHRVDGTTGLAWSDGPGLDWSRPATPAQLQANGLSADTVACWHEHAGWVRPPQLIAHLLNDPAIRWRGSAAVAELRRTTVDGQPLWQALDAEGHVLAEAELAVVCAGHHTGPLTHAHWPMNPLRGQLAWGLHAQAPAGAPWPPQPLNGNGNLVPRVPLQDGAGWVLGSTFERLKTALPPSPDDHAKGLATNQAKLHALLPPLGAAMDAAFSQAATAPDGPVRTWAAVRCGALDRRPIVGPVDSVRQPGLWLCTAMGARGLTLSLLCGELIAARLHSEPLPLDAPLARALSSERWLGYEPQ
What is the function of this protein?
Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA.  Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
What are the official names of this protein?
tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC, tRNA mnm(5)s(2)U biosynthesis bifunctional protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the DAO family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM38A_XENLA
Sequence: MELLSALSLDDLAASFSKLPVFPLFDVAYYIISILYLKYEPGAVDLSKRSPVASWLCAMLYCFGSYILADVLLGESPIHYFSNNANILLASAVWYLTFFCPLNIFYKIVSFLPVKLVLVGMKEVVRVRKIAMGIHHAHHHYHHGWVIMVLIGWVKGSGVALMSNLEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQAHWLPISKAYLIFFFTLFMAVCKIYMTATHSHGSPFAIFESGICYVLFAAANGDHDDHGNHHHHHDDHDVSHSAGKSKEEHNEGTRKRKTKKAE
What is the function of this protein?
Monovalent cation channel required for maintenance of rapid intracellular calcium release.  May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
What are the official names of this protein?
Trimeric intracellular cation channel type A, TRIC-A, TRICA, Transmembrane protein 38A.
What is the protein family that this protein belongs to?
Belongs to the TMEM38 family.
What are the subcellular locations of this protein?
Sarcoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane.
Protein: CLPB_MYCPN
Sequence: MDFSFTPTPDKRDFLKEMGRSINDEVLKNKVDPIIGRDNEIRRLIEILSRKNKNNPVLIGEPGVGKTAIVEGFVRRVVNNDVPLNLRDVEIYELSLSGLIAGTQYQGEFEKRVNGILKQVKESNGKIILFIDEIHQIVGLGRNSSSGAMDIANILKPMLARGEIKVIGATTLKEYREYVEKDGALERRFQKILVSEPSQQEALTIMRGLKTRWELFHNLTIFDSALVAAVEMSARYIPDRNLPDKAIDLIDEASAKIKTEMASEPVVIDTLKREIINLETEYAALKQDKENADNKKKQGHLDNLKQQLDELKKKRDSLTAEWKKEKTNFESINKLKKEIEDLQTRLELYQTEGNYEAASKILYYDIPKLKNQLEQAQKKYVDSKHDLFKTEVSENEVAEVVSQATGIPLKKLLETEKEKLLHLGDEIKKRVKGQDAAVETVVNTVMRGRVNLNDPNRPIGSFIFLGSTGVGKTELAKSLAEVLFDNEKAMIRFDMSEYMEKHSVAKLIGAPPGYVGYEQSGLLTEAVRRKPYCVLLFDEIEKAHPDVTNILLQVLDDGTLKDSQGRLVNFKNTMIIMTSNLGSNYIMENKRDLAMEALKKHFRAEFINRIDEIVFFSVLQKTTVLEIITNLLDQLNQRLAKQNLKFTFDPKLNEFIYKSSFDEQFGARPIKRFIDRQIATLIAKQILEGIITKDVSYNVIVEKDKVAIVANKVKS
What is the function of this protein?
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.  Acts before DnaK, in the processing of protein aggregates.  Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity).
What are the official names of this protein?
Chaperone protein ClpB.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL101_ORYSI
Sequence: MGRRPARCYRQIKNKPYPKSRYCRGVPDPKIRIYDVGMKKKGVDEFPYCVHLVSWEKENVSSEALEAARIACNKYMTKNAGKDAFHLRVRVHPFHVLRINKMLSCAGADRLQTGMRGAFGKPQGTCARVDIGQVLLSVRCKESNAKHAEEALRRAKFKFPGRQKIIHSRKWGFTKFTREEYVKLKAEGRIMSDGVNAQLLGSHGRLAKRAPGKAFLAETIQASA
What are the official names of this protein?
60S ribosomal protein L10-1, Protein QM, Putative tumor suppressor SC34.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: YIM4_BPPH1
Sequence: MGQVEKARQGQFARPHHSDSQRRVRAWSRIQRRARSF
What are the official names of this protein?
Uncharacterized immunity region protein 4.
Protein: MTND_STRMK
Sequence: MSRLRIYDDTRPESPLLDTQDGAVIAAELQKIGVTFERWQATAPVAPGASQEEVFAAYRADIDRLVAERGFKSVDVASIAPDNPNRAELRKKFLDEHFHKEDEVRFFVAGSGLFTLHVGDKVYEIECVKDDLIAVPDGTTHWFDMGDEPSFVAIRFFTEPDGWVGHFTGTDIAQKFPRYVPTQAS
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: DID_ATHSQ
Sequence: MIQVLLVIICLAVFPYQGSCIILESGNVNDYEIVYPKKLIVLPTGAMNSPHPCCDPVTCKPKKGEHCISGPCCRNCKFINSGTICKRARGDDMNDYCTGTTPDCPRNPYKD
What is the function of this protein?
Inhibits ADP-induced platelet aggregation in human platelet-rich plasma (IC(50) is 8 uM).
What are the official names of this protein?
Disintegrin DS-AS.
What is the protein family that this protein belongs to?
Belongs to the disintegrin family. Dimeric disintegrin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LANB_STRP9
Sequence: MTKEHEIINSIQEVSLEELDQIIGAGKNGVFKTISHECHLNTWAFLATCCS
What is the function of this protein?
Lanthionine-containing peptide antibiotic (lantibiotic) active on certain Gram-positive bacteria.  The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores (By similarity).
What are the official names of this protein?
Lantibiotic streptococcin A-M49, Antibacterial peptide A-M49.
What is the protein family that this protein belongs to?
Belongs to the type A lantibiotic family.
What are the subcellular locations of this protein?
Secreted. Cell surface. Note=Either cell associated or in a released extracellular form.