PharMolix/UniProtQA huggingface dataset:
Protein: MLTF_SALAR
Sequence: MKKLKINYLFIGILTLLLAAALWPSIPWFGKTENHVAAIQARGVLRVSTIDSPLTYAVVNGKKYGLDYELAQQFANYLGVKLKITVRQNISQLFDDLDNGNADLLAAGLVYDSARVKKYQPGPMYYSVSQQLVYRVGQYRPRSLATVTENQLTIAPGHVVVNDLQRLKETKFPDLSWKVDDKKGSTTLLEDVINGKLDYTIADSVAISLFQRVHPELAVALDVTDEQPVTWFSRLDDDNTLSAALLDFFNSINEDGSLARIEEKYLGHGDDFDYVDTRSFLRAVDNVLPELEALFKKYAKEIDWRLLAAISYQESHWDPQATSPTGVRGLMMLTKNTAQSLGLTDRTDAEQSISGGARYLEDMMAKVPETVPEDERIWFALAAYNMGYAHMLDARALTVKTKGNPDSWTDVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQEAEAMKLAQDYPAASPEELNKAPFPFISFLSQSSGYLTHSPSLLFTPQKKEEK
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: CHIA_ARAHY
Sequence: MTAQGNKPSSHDVITGRWTPSAADRAAGRVSGFGVITNIINGGLDC
What is the function of this protein?
Defense against chitin-containing fungal and bacterial pathogens.
What are the official names of this protein?
Endochitinase 1A, CHIT 1A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.
Protein: PYRB_LEPIC
Sequence: MYYNHKNVLDTEQFSKPDLDFLIGKIRVMERLVEQNKAFGILTGKLLASLFFEASTRTRLSFEAAMERLGGRVISTVGFQFSSISKGETLYDTMKMVEAYADIAVIRHPVEGSSRIAAGAVKIPVINAGDGAGQHPTQAILDLYTIISEKGTLDGLKVAFIGDLKYGRTIHSLINLLRHYKVRLFLISPPELALPESYKKALQGYSLTLEETTDIKAVWDCDVAYVTRIQEERFPDHKEYERLKDLFKINKELILASKKETTVLHPLPRVNELSTDVDDLPNAAYFRQARYGVVSRMTLLCLSLGQDF
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y646_MYCPN
Sequence: MNKKSIWSKTAFGSLFLLLGTAFTACSNYDFQANLTSLNQLRTSANKDINLTQDKNTLIDALKTAFENNSEGTTKVLLDAWKFSLYDAKILEKQDPVKFVKAFGSGKSKEDIEPSAGVRGLRFVERFGDNTASLIKNAILLDQQKVEVFNIRFKSSRDFTIQIKLNAKGNYKKSEVEKYKSQIGVQDNELGDKEEGTLEADLIFTYTPPASNLFSKSNFDKLTKSINFNTNLKLEMVGKDEVMRKILNSSAFTNNLASVNYPNQAVNLLPYVLYSIL
What are the official names of this protein?
Uncharacterized lipoprotein MG440 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the MG439/MG440 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: HCP_THEYD
Sequence: MFCRQCEQTANPCTKLGVCGKQPDTAYLQDLLTYALQGLATYAKEALKESSQTQNVMKRINKFTVEALFATLTNVNFDSEAIKNFIYEAVKLRDELKQMGFKVQETESCKFQPADNLQELVKQGEEANQKIFHSSSNEDVQSLKEITLYSLRGIAAYTDHAQILGQEDEKVYAFIYEALDAMQRNGDLDFWLNMVLRAGEINLRAMELLDAANTGRYGHPVPTPVPLGHKKGKAIVVSGHDLRDLELLLQQTEGKGIYVYTHGEMLPCHGYPELKKYKHFYGHYGTAWQNQQREFAQFPGAILMTTNCIIKPQESYKDRIFTTGVVGWPGVKHIKDKDFTPVIEKALELPGFTEDKEDKTVMVGFARNSVLSVADKVIELVKAGKIRHFFLVGGCDGAKPGRSYYTEFVEKTPKDTIVLTLACGKFRFFDKELGSINGIPRLLDVGQCNDAYSAIQIALALSKAFNVSINELPLSLILSWFEQKAVAILTTLLYLGIKNIRLGPTLPAFVSPNVLKVLVDNFGIKPIKTAEEDLKDILR
What is the function of this protein?
Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
What are the official names of this protein?
Hydroxylamine reductase, Hybrid-cluster protein, HCP, Prismane protein.
What is the protein family that this protein belongs to?
Belongs to the HCP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_BACP2
Sequence: MGQEKHVFTIDWAGRQLTVETGQLAKQANGAVLVRYGDTAVLSSATASKEPKPLDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPIRPLFADGFRNEVQVISIVMSVDQDCSSEMAAMFGSSLALCVSDIPFEGPIAGVTVGRVDGKFIINPNVEQLEQSDINLVVAGTKDAINMVEAGADEVPEETMLEAIMYGHQEIKRLIEFQEEIVKAVGKAKIDIPLYEVDQTLADEVKALAETDLLKAIQVHEKHAREDAISAVKKAVVEKFEEEDRDEATIKQAKDVLNKLVKNEVRRLITEEKVRPDGRGVDQIRPLSSEVGLLPRTHGSGLFTRGQTQALSICTLGALGDVQILDGLGVEESKRFMHHYNFPQFSVGETGPMRGPGRREIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKSGEYYTVLTDIQGMEDALGDMDFKVAGTSKGVTALQMDIKIDGLSKDILEEALQQAKKGRMEILDSMLSTIPTSRGELSRYAPKILTMKINPDKIRDVIGPSGKQINKIIEDTGVKIDIEQDGTIFISSTEEDMNQKAKKIIEDLVREVEVGQLYLGKVKRIEKFGAFLEIFSGKDGLVHISELALDRVGKVEDVVKIGDELLVKVTEIDKQGRVNLSRKAVLREEKEKEEKQS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_ESCF3
Sequence: MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVFGDISGQTPVLARVHSECLTGDALFSLRCDCGFQLEAALTHIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVDAVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPKNAHYLDTKAAKMGHLLGKTE
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: UVRC_CITK8
Sequence: MSVLFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKVFPIRQCENSVYRNRSRPCLQYQIGRCLGPCVEGLVSEDEYAQQVEYVRLFLSGKDDQVLTQLIARMEKASQNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPNGTELGEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLSELAGRRINVQTKPRGDRARYLKLARTNAATALISKLSQQSTITQRLTALASVLKLPAVKRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIEESKIPDVILIDGGKGQLGQAKAVFAELDVPWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAISGHRKKRAKVKNTSTLETIEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFYSLKH
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_ECOHS
Sequence: MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: NANGN_HUMAN
Sequence: MHRARWLTPVIPALWEAEAGRSRGQEIETILANKKQSAMPWDQDPEQSTGNYSEDEQNGKQKWREEGEAGRKREREKEEKNEKELQDEQENKRKRENEKQKQYPEKRLVSKSLMHTLWAKFKLNRCPTIQESLSLSFEFDMTHKQISQWFCKTRKKYNKEMSKRKHKKKHMRWRSLCCQGWSRTPALK
What are the official names of this protein?
NANOG neighbor homeobox, Homeobox protein C14.
What are the subcellular locations of this protein?
Nucleus.
Protein: SECA2_STAEQ
Sequence: MAKGVNQIINNIRLRKLRKILNQINALSEEFSNFSDEALQAKTKEFKVYLNDNKASLNHILPQAYATVREASKRVLGMYPKDVQILGAIAMHQGNIAEMQTGEGKTLTATMPLYLNALTGKGAYLITTNDYLAKRDFLEMKPLYEWLGLSVSLGFVDIPEYEYAENEKYELYHHDIVYTTNGRLGFDYLIDNLADDIRAKFLPKLNFAIIDEVDSIILDAAQTPLVISGAPRVQSNLFHIVKTFVETLEKDKDFIVNFNKKEVWLTDEGSEKASHYFKVNSIYQQQYFDLVRMIHLSLRAKYLFKYNLDYFIFDGEIVLIDRITGRMLPGTKLQSGLHQAIEALENVEISQDMSVMATITFQNLFKQFDEFSGMTGTGKLGEKEFFDLYSKVVIEIPTHSPIERDDRPDRVFANGDKKNDAILKTVIGIHETQQPVLLITRTAEAAEYFSAELFKRDIPNNLLIAQNVAKEAQMIAEAGQLSAVTVATSMAGRGTDIKLSKEVHDIGGLAVIINEHMDNSRVDRQLRGRSGRQGDPGYSQIFVSLDDDLVKRWSNSNLAENKNLQTMDASKLESSALFKKRVKSIVNKAQRVSEETAMKNREMANEFEKSISVQRDKIYAERNHILEASDFDDFNFEQLARDVFTKDVKNLDLSSERALVNYIYENLSFVFDEDVSNINMQNDEEIIQFLIQQFTQQFNNRLEVAADSYLKLRFIQKSILKAIDSEWIEQVDNLQQLKASVNNRQNGQRNVIFEYHKVALETYEYMSEDIKRKMVRNLCLSILAFDKDGDMVIHFP
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA 2.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
Protein: TRPD_CORA7
Sequence: MTDNKALKILQEFLDISEPTLEQAIEVFTPLTVGEYDDIHIAALLTHIRTRGETFADVAGAARAFLNAGHPFPITGKGLMDTAGTGGDGANTINVTTGASLVASAGGVKMVKHGNRSVSSKSGSADVLEALGIPLNLDPDRAVRQLEASNFTFLFAPAYNPAVAHVQPVRKGLGISTLFNTMGPLLSPGRPEFQIMGIANPEQGQLIAEVFKDLGRTRALVVHGAGTDEIAVHGTTQVWELRDGTISHYELTPEDLGISHHELADLAGGNGEENAKALRAVFAGTGEPAHHDAIAATAGAMFYLNGTTDSIHEGVTHADQLIKNGTVAAWLKKHEEANYGSADRA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: CYSD_METEP
Sequence: MSAAVAAPARTRLTHLQRLEAESIHIFREAVAEAENPVMLYSIGKDSSVLLHLALKAFAPGRLPFPLMHIDTTWKFREMIAFRDRRAKELGLELIVHTNQDGLAKGVGPVSHGSEVHTDVMKTQALRQALDKYKYDVAFGGARRDEEASRAKERIVSLRNGQHRWDPKRQRAEPWHLYNFKKRRGESFRVFPLSNWTELDIWLYIEQENIPIVPLYFAAERPVVERDGQLIMVDDERFPLEPGETPQQRQVRFRTLGCYPLTGAVESPAATLPEIIGETLAARTSERQGRVIDKDGAGAMERKKQEGYF
What is the function of this protein?
With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway.  APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.
What are the official names of this protein?
Sulfate adenylyltransferase subunit 2, ATP-sulfurylase small subunit, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysD subfamily.
Protein: YIPF7_HUMAN
Sequence: MDLLKISHTKLHLLEDLSIKNKQRMSNLAQFDSDFYQSNFTIDNQEQSGNDSNAYGNLYGSRKQQAGEQPQPASFVPSEMLMSSGYAGQFFQPASNSDYYSQSPYIDSFDEEPPLLEELGIHFDHIWQKTLTVLNPMKPVDGSIMNETDLTGPILFCVALGATLLLAGKVQFGYVYGMSAIGCLVIHALLNLMSSSGVSYGCVASVLGYCLLPMVILSGCAMFFSLQGIFGIMSSLVIIGWCSLSASKIFIAALHMEGQQLLVAYPCAILYGLFALLTIF
What are the official names of this protein?
Protein YIPF7, Five-pass transmembrane protein localizing in the Golgi apparatus and the endoplasmic reticulum 9, YIP1 family member 7.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane. Golgi apparatus, trans-Golgi network membrane. Note=Evenly distributed between cis- and trans-Golgi apparatus.
Protein: B3GL1_MOUSE
Sequence: MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
What is the function of this protein?
Transfers N-acetylgalactosamine onto globotriaosylceramide (PubMed:9417047).  Plays a critical role in preimplantation stage embryonic development (PubMed:11463849).
What are the official names of this protein?
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1, Beta-1,3-GalNAc-T1, Beta-1,3-galactosyltransferase 3, Beta-1,3-GalTase 3, Beta3Gal-T3, Beta3GalT3, b3Gal-T3, Beta-3-Gx-T3, Brainiac 1, Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase, Globoside synthase, UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: BHE23_HUMAN
Sequence: MAELKSLSGDAYLALSHGYAAAAAGLAYGAAREPEAARGYGTPGPGGDLPAAPAPRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALDEMRRLVAFLNQGQGLAAPVNAAPLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCKHCHEKP
What is the function of this protein?
May function as transcriptional repressor.  May modulate the expression of genes required for the differentiation and/or maintenance of pancreatic and neuronal cell types.  May be important for rod bipolar cell maturation (By similarity).
What are the official names of this protein?
Class E basic helix-loop-helix protein 23, bHLHe23, Class B basic helix-loop-helix protein 4, bHLHb4.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRMA_ALKCK
Sequence: MKWAEFRVHTTQEAVEPVSNILHELGAAGVAIEDPQDLVTEWSVKYGEVYELSPEDYPDEGVMVKAYFPMGATFKETIAEVRRRVHNLVSFQIDIGHGTMDYTEVKEEDWATAWKSFYHPVQVTEQVTIVPTWEEYSARPGEIVIELDPGMAFGTGTHPTTILSLQALEQAVKQGDAVIDVGTGSGILAIAAWKFGAESITALDLDEVAVNSAKANVALNSASDFVHVQQGNLLDDVASESADVLVSNILAEVILQFTADAYRVVKRGGLFLTSGIISSKREAVEGALKAVGFLIQEVNELDDWVAIVAQKPSQA
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_ARTS2
Sequence: MSTLITNIAELMTQDAEHRVLKDAAVVIEGERISWIGPSSAAPAADDEVDAGGRALLPGWVDSHTHLIFAGDRTAEFEARMAGESYSAGGIAVTTGATRGTSDFDLTRLALGRVAEAVSQGTTYLETKTGYGLDVENETRSARIASTVADEVTYLGAHLVPAGADADEYTDLVCGPMLAAVRPYVSWADVFCEQGAFNEQQSRRVLQACKDAGMGLRVHGNQLGEGPGVRLAVEFGAASVDHVNYLSAADVEALAGSWSGWQGAGTRGTVATCLPACDLSTRQPLAPGRELLDAGVPIALASNCNPGTSYTSSMAFCVTTAVLQMRLSVHEAVRAATYGGALALRREAGNDVDGERAVGSVAIGHRADLHLLNAPSATHLAYRPGIPLTHAVWRAGVRAR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_PARUW
Sequence: MDVLKITGGIPLKGQVKAAGAKNAMTKLLVASLLSDKKCTFYNVPNIGDVEVTVSLCQEIGMEVRWDRAAGIMEVITKELKTSYIPQRFSGSNRIPILMIGALLGRTDQDIIVPTAGGCPIGQRPVDFHIQALEQLGAVIEYRGMKREGAYFAHAHNGLKGTLITLPYPSVGATENTILAGITARGVTVIKNAAIEPEIVELILFLQKLGAIITIDVDRTIRIQGTRRFYEVEHTVIPDRIEAASWGMAAISSKGKVFVEGAQHLNMITFLNKLREVGGGFDVRSNGIEFFYDGPLQGGLHLETDVHPGFMTDWQQPFVVLLTQSSGTSVVHETVYENRFGYTDTLKEMGADITPFRQCLGGKSCRFASQSFSHSAIIKGATPLVGKEIRIPDLRAGFAYIMAALIANDTSTISGLPFIQRGYENFIGKLADLGANVSLVEEEKNVKEMPENSSKLPLFAELQVN
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BUB2_YEAST
Sequence: MTSIEDLISNPPLLLHSSLSQLRYLILSEGLPISEDKQQQRTRCYVWTVLSQTSMEASTQRYLALLKLGPPSTTIYQKIKNDTSRTFQTDPNFRNRVSEDALIRCLSCFAWQTQQRRQKTRFGRIPVSTYVQGMNVLLAPLLYSCPSEPMAYQLFTKLCYEMIPTYLTKNLNGAQNGAKLLDISLRIIDPKLSKFLSDNLLTAEIYGMPSILTLSSCNKPLDQVIKLWDFMFAYGFHMNILFVVAFLVKMRSKVFKSDSPVNLLRQFPDFDADEIIRLGVGFIAKIPAQIYDLLVDHLTDPDIYIP
What is the function of this protein?
Part of a checkpoint which monitors spindle integrity and prevents premature exit from mitosis.  This cell-cycle arrest depends upon inhibition of the GTP-binding protein TEM1 by the BFA1/BUB2 complex.
What are the official names of this protein?
Mitotic check point protein BUB2, Cell cycle arrest protein BUB2.
What is the protein family that this protein belongs to?
Belongs to the BUB2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, spindle pole.
Protein: TSGA_SALEP
Sequence: MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFHLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFILMVLAVAGLMFSHSLALFSAAMFVLGLVSGITMSIGTFLITQLYEGRQRGSRLLFTDSFFSMAGMIFPMVAAFLLARSIEWYWVYACIGLVYLAIFILTFGCEFPALGKHAQHSQAPVAKEKWGIGVLFLAVAALCYILGQLGFISWVPEYAKGLGMSLNDAGALVSDFWMSYMFGMWAFSFILRFFDLQRILTVLAGMAAVLMYLFITGTQAHMPWFILTLGFFSSAIYTSIITLGSQQTKVASPKLVNFILTCGTIGTMLTFVVTGPIVAHSGPQAALLTANGLYAVVFVMCFALGFVSRHRQHSAPATH
What are the official names of this protein?
Protein TsgA.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TsgA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COBQ_SINFN
Sequence: MTRAIMLQGTGSDVGKSVLVAGLCRLAANRGLKVRPFKPQNMSNNAAVSDDGGEIGRAQWLQSLAARVPSSVHMNPVLLKPQSDVGSQVILQGKVAGQAKGREYQALKPKLLGAVMESFGRVSAGADLVVVEGAGSPAEINLRAGDIANMGFATHANVPVVLVGDIDRGGVIASLVGTHAILPEEDRRMVAGYLINKFRGDVSLFDDGIAAVGRFTGWPCFGVVPWLKSAARLPAEDSVVLEKLARGSGKALKVAVPVLSRIANFDDLDPLAAEPEVELVFVRPGMSLPQDAGLVVIPGSKSTISDLKNFRAQGWDRDLERHVRRGGRVIGICGGYQILGTRVADPLGIEGSEREIAGLGLLSVETEMAPEKTVRNSRAWSLEHDVGLEGYEIHLGKTTGADCERAPVTIDGRPDGAMSADGRVMGTYLHGLFGSDAYRAALLKSLGIEGGGANYRQSVDSALDEIAAELEGVLDGAWLNRLLG
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: SINE4_ARATH
Sequence: MEEREESSSHEHLKEKLRELEEEWTAMKTGKNSSAVSWITVEDALEYVENSPRNLMLSLQHKPKAEMIQEISPLRRKLFHDSDDDDQTKKTTLLSHSSCWSSNVTSSSDTTKAKKKTTIRRFVSVTMVLLLSWVLVVLMNHFDHLSMNTQIITLVPT
What are the official names of this protein?
Protein SINE4.
What are the subcellular locations of this protein?
Nucleus membrane; Single-pass membrane protein.
Protein: LELP1_MOUSE
Sequence: MSSDKSSDSKNGLKNCDPRCEQKCETKCQPSCLNKLLQRCSEKCSLDKCPPSPNCPPCPPCPPCPLVCQSQCSTPTSPLCPPLCSPRCSGTLACCPPSCPQKGCVKPCPPKCPSPCLPRK
What are the official names of this protein?
Late cornified envelope-like proline-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the cornifin (SPRR) family.
Protein: SYV_BDEBA
Sequence: MKMSEQLSDRYNPADVESRTYEWWEKNGYFKAQDQSTKPPFSIILPPPNVTGFLHMGHALDHTIQDMMIRWKRMNGYNTMWLPGTDHAGIATQSVVERELKKDGVTRHDLGREKFVEKVWDWKHQYGNRIYGQMRRLGDSCDWDRAVFTLDEGVSKAVRKVFVSLHKKGLIYRGQRLVNWSGPLETAISDLEVEHKQIKGSLYHVKYPLEDGSGFLVVATTRPETMLGDSAVCVHPEDERYKHLIGKNVLLPLTNRKIKIIADTYVDKEFGSGVVKITPAHDFNDYKIGKTHNLEFINILTKKAEINENGGVYAGLKVQEARKRILEDLKAQDLLEKEEPHVHSVGHCSRSGAVVEPYLSEQWFVKMEALAVPAKRVAENGTIRFEPESWTKVYLHWLNNIEDWCISRQLWWGHRIPVWYCEDCNHQTVAETDVTACEKCGSTKLHQDDDVLDTWFSSALWPFSTMGWPNETETLKTFYPTSYLVTGHDIIFFWVARMIMMGLEFQRDVPFRTVYIHGLVRDSQGRKMSKSLGNSIDPVEMIEKHGADALRFTFAAHLYSGKDFKFSEQRLEGYRNFMNKVWNAARFALSNLSDFKAPTEGVKALPNKVHISVFDQWIITKLEEVTKTVEEAMEQERFSDASTALYQFIWNQFCDWYIEFTKPILNGNNAEEKAATQLVIAQVLNRIMRLLHPFAPFISEEIYQKLPIKGTACIVDQYPNARNDKEFLSLGSAQAALEIDIVKEVITAIRNIRGENRISPAVKLNVRLGVTNDQTQKILGNNRTALMTMGRLENMEIGPEGDMMKCAVAPVVVKDASVKVIIPLEGLVDFDEEVKRINKSIEKLTRDIGMLSGKLSNEKFVANADEEVVAADRALLAQSKVQLDSLRDALTRFQ
What is the function of this protein?
Catalyzes the attachment of valine to tRNA(Val).  As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
What are the official names of this protein?
Valine--tRNA ligase, Valyl-tRNA synthetase, ValRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KATG_RHOE4
Sequence: MSDSCPVAHDGNTASTSESENPAIPSPTPTGNRPRTNRDWWPNQPDLSVLHAHSSKSNPMGADFDYAQEFAKLDVEALKRDVIALMTASQDWWPADYGHYGGLFVRMSWHAAGTYRIADGRGGGGQGAQRFAPLNSWPDNASLDKARRLLWPVKQKYGKQVSWADLLVFAGNCALESMGFTTFGFGFGREDIWEPEEIYWGPEDTWLGDERYSGDRELSGPLGAVQMGLIYVNPEGPNGQPDPVAAARDIRETFARMAMNDVETAALIAGGHTFGKTHGAGPADLVGPEPEGAPVEQQGLGWKSAFGTGVGKDAITSGLEVVWTPTPTKWDNTFLEILYGYDWELTKSPAGAWQWIPKDGAGAGTIPDPFDSSAGRTPTMLTTDLSLRLDPTYEKITRRWLDHPEEFAEEFAKAWYKLLHRDMGPVTRYLGPWVPEPQLWQDPVPSADDQLIGDADIAILKSRLLDSGLSVSQLVSTAWASAASFRSTDMRGGANGARIRLEPQKNWEVNEPATLSAVLQTLERVQQEFNQAGGAKVSLADLIVLGGTAAVEQAAKNAGQDITVSFTPGRTDATQEQTDVDSFEVLEPRADGFRNYLKGGEKIPAEILLVDRAYMLSLTPPEVTVLVGGLRALNANFGKTGHGVFTDRPETLTNDFFVNLLDMGTEWKPSKTEENVYDGVDRATGDPKYTATAVDLVFGSNSQLRALSEVYASEDAKQKFAEDFAAAWTKVMDLDRFDVN
What is the function of this protein?
Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.
What are the official names of this protein?
Catalase-peroxidase, CP, Peroxidase/catalase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Peroxidase/catalase subfamily.
Protein: RNH2_RICAH
Sequence: MEVDLLHFEKKYHNYIVAGIDEAGRGPLAGPVVASAVIIDNANIIHGIKDSKKLSKKKRALLYEQITSNYVWAVAIITHTEIDKINILEATKKACSIAAANLNVKPEIVLVDGNMQFSDERFISIVNGDNLSLSIAAASIIAKVTRDRLMLELSAKFPQYLWHKNSGYGTKEHLEAINKYGLSPYHRKSFKCC
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CD7_HUMAN
Sequence: MAGPPRLLLLPLLLALARGLPGALAAQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQSQGWHRCSDAPPRASALPAPPTGSALPDPQTASALPDPPAASALPAALAVISFLLGLGLGVACVLARTQIKKLCSWRDKNSAACVVYEDMSHSRCNTLSSPNQYQ
What is the function of this protein?
Not yet known.
What are the official names of this protein?
T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RS7_EXIS2
Sequence: MPRKGQVERRDVMADPIYNSKLVTRLINRLMLDGKKGTAQQILYKAFEAIAERSGRDAMEVFEEAMNNIMPVLEVKARRVGGANYQVPVEVRPERRTTLALRYLVNYSRLRNEKTMDARLANEIMDAANNTGASVKKREDMHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.