PharMolix/UniProtQA huggingface dataset:
Protein: PURQ_EXISA
Sequence: MKFAVIVFPGSNCDLDMYHAVKDVLGEEAEYVFHTETSLEGFDGVLLPGGFSYGDYLRCGSIAQFSPIMAEVKRFAEEGRPVLGVCNGFQVLVEAGLLPGVLMRNRDLKFMCKTVDLVVENNETMFTSEYAAQETIRVPIAHGEGNYYCDDATLAALKANGQIAFTYKENPNGSVENIAGITNEAGNVLGMMPHPERAVEALLGGEDGKRLFTSIVKWGARHVTYN
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSA2_DICDI
Sequence: MPQGDHIELHQKRFGRRLDHYEKVRKKTARAAHKRSAIAQKVTGLKAKLYNKKRYSEKAEMKKTIAMHQERTNKKASDDKVKEGAVPAYLLDREGVSRAKVLSNMVKQKRKEKAGKWDVPLPKVRAISEDEMFKVVKSGKRQKKAWKRFVTKVTFVGEGFTRKPPKYERFIRPTGLRFKKAHVTHPELKSTFYLDILSVKKNPQSPTYTQLGVITKGTILEVNVSDLGLVTQTGKVVWGKMAQVTNNPENDGCINAVLLV
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit.  May play a part in the quality control of pre-60S particles (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein NSA2 homolog.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RPIA_PYRFU
Sequence: MNVEEMKKAVARAALEFIEDDMVVGLGTGSTTAYFIRYLGEMIEKGKVEDIYGVPPPIKQKFLRMESGVPVLSLDQVDAIDIAVDGADEVDPNLNLIKGRGAALTMEKIIEYRAGTFIVLVDESKLVDYLCQKMPVPIEVIPAAWKAILEELSIFNAKAELRMGVKKDGPVVTENGNFIIDAKFPRIDDPLDMEIELNTIPGVVENGIFADIADIVLVGTKEGVKRLER
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: PSBJ_OENEH
Sequence: MADTTGRIPLWIIGTVAGILVIGLIGIFFYGAYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL2_COXBR
Sequence: MALVKTKPTSPGRRFVVKVVHPELHKGDPYAPLVESKNRINSRNNQGRITVRRRGGGHKRNYRIIDFKRDKEGIEGKVERLEYDPNRSAHIALVLYPDGERRYIIAPKGVHKGSKVVSGREAPIRPGNCLPLQNIPLGATIHNIELKPGKGAQLVRSAGASAQLAAKEGIYAIIRMRSGETRKILAVCRACIGEVSNSEHNLRSLGKAGAKRWRGRRPTVRGVAMNPVDHPHGGGEGKTSGGRHPVSPTGKPTKGYKTRRNKRTSNMIIRDRRKK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: RL5_CAMJD
Sequence: MMRLKEKYNQSIKPALVKEFDIKNPMLIPVIEKVVISVGAGELAKDQKVLQNVADTISLIAGQKAVITKAKKSVAGFKVREGFPIGVMVTLRKENMYAFLDKLISIALPRVKDFRGLSRDGFDGRGNYNFGLDEQLMFPEVEYDKILRTHGMNISIVTTAQNDKQAQKLLELIGVPFTKGK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: MAF_CHICK
Sequence: MASELAMSGSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPMSTPCSSVPPSPSFSAPSPGSGTDQKTHLEDYYWMTGYPQQLNPEALGFSPEDAVEALINSSHHPLPGAFDGYARGQQLAAAAGGSVPAEEMGSAAAVVSAVIAAAAAQGGAPHYHHHHHHPHHGGGGGGGGHPHGAAPGSAPPSSASSSAAGSGGGGGGGGGGAGGLHHPHHGGGGGGGGLHFDDRFSDEQLVTMSVRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVEHLKQEISRLVRERDAYKEKYEKLVSNGFRENGSSSDNPSSPEFFM
What is the function of this protein?
Acts as a transcriptional activator or repressor.  Positively regulates the expression of alpha A crystallin genes during lens fiber cell differentiation.  Binds to Maf recognition elements (MARE).
What are the official names of this protein?
Transcription factor Maf, V-maf musculoaponeurotic fibrosarcoma oncogene homolog.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOI_XANCP
Sequence: MMNKITHYFKSLLLLELLGGLWLTLKYTFKPKYTVLYPMEKFPQSPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITIDSAKREDGTRRTTRYDIDLFKCIFCGFCEESCPVDSIVETHILEYHFEKRGENIVNKPQLLAIGDRLEAEIAERRAADAAFR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: DER_STAA1
Sequence: MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: RS20_CHLTE
Sequence: MPLHKSAEKRLRQAARRNERNRARKKELKGVLKNMQKLIDANAAKSEVEAAYKAAVQKLDRLGVKRYIHPNKASRKKAQLTKALNNYTPTAS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: DRA_HUMAN
Sequence: MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNAAERRGPL
What is the function of this protein?
An alpha chain of antigen-presenting major histocompatibility complex class II (MHCII) molecule.  In complex with the beta chain HLA-DRB, displays antigenic peptides on professional antigen presenting cells (APCs) for recognition by alpha-beta T cell receptor (TCR) on HLA-DR-restricted CD4-positive T cells.  This guides antigen-specific T-helper effector functions, both antibody-mediated immune response and macrophage activation, to ultimately eliminate the infectious agents and transformed cells (PubMed:29884618, PubMed:17334368, PubMed:8145819, PubMed:15322540, PubMed:22327072, PubMed:27591323, PubMed:31495665, PubMed:15265931, PubMed:9075930, PubMed:24190431).  Typically presents extracellular peptide antigens of 10 to 30 amino acids that arise from proteolysis of endocytosed antigens in lysosomes (PubMed:8145819).  In the tumor microenvironment, presents antigenic peptides that are primarily generated in tumor-resident APCs likely via phagocytosis of apoptotic tumor cells or macropinocytosis of secreted tumor proteins (PubMed:31495665).  Presents peptides derived from intracellular proteins that are trapped in autolysosomes after macroautophagy, a mechanism especially relevant for T cell selection in the thymus and central immune tolerance (PubMed:17182262, PubMed:23783831).  The selection of the immunodominant epitopes follows two processing modes: 'bind first, cut/trim later' for pathogen-derived antigenic peptides and 'cut first, bind later' for autoantigens/self-peptides (PubMed:25413013).  The anchor residue at position 1 of the peptide N-terminus, usually a large hydrophobic residue, is essential for high affinity interaction with MHCII molecules (PubMed:8145819).
What are the official names of this protein?
HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA.
What is the protein family that this protein belongs to?
Belongs to the MHC class II family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Early endosome membrane; Single-pass type I membrane protein. Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Autolysosome membrane; Single-pass type I membrane protein. Note=The MHCII complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation (PubMed:9075930, PubMed:18305173). Component of immunological synapses at the interface between T cell and APC (PubMed:15322540, PubMed:29884618).
Protein: FLGH_BRUC2
Sequence: MNKAILAVAMVLLLAGCATKPEEIGRAPDLSPVAAHLGMQNNPQFNGYPARPGKASYSLWDQRSTNFFKDPRAATPGDVLTVIISINDRANLDNKTDRERVSKGIYGGGGSFATSSITGAAAGGDMDASINTHSDSKSKGKGTIERSEDIRLQIAAIVTDTLPNGNLIIRGSQEVRVNNELRVLNVAGVVRPRDISGNNTISYDKIAEARISYGGRGRLSEIQQPPYGQQILDQFSPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: YNJD_ECOLI
Sequence: MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLFSWMIGALAEQFSCTGELWLNEQRIDILPTAQRQIGILFQDALLFDQFSVGQNLLLALPATLKGNARRNAVNDALERSGLEGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEPFSRLDVALRDNFRQWVFSEVRALAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR
What is the function of this protein?
Probably part of a binding-protein-dependent transport system YnjCD.  Probably responsible for energy coupling to the transport system.
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YnjD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: VXIS_BPML5
Sequence: MPPRASIQETADYLGVSTKTVRNYIADGRLKAVRLGPRLIRVERESVEELMRPIGK
What is the function of this protein?
Excisionase and integrase are necessary for the excision of prophage from the host genome by site-specific recombination at the att site.
What are the official names of this protein?
Excisionase, Gene product 36, Gp36.
What is the protein family that this protein belongs to?
Belongs to the L5likevirus excisionase protein family.
Protein: SERC3_PONAB
Sequence: MGAVLGVFSLASWVPCLCSGASCLLCSCCPNSKNSTVTRLIYAFILLLSTVVSYIMQRKEMETYLKKIPGFCEGGFKIHEADINADKDCDVLVGYKAVYRISFAMAIFFFVFSLLMFKVKTSKDPRAAVHNGFWFFKIAALIGIMVGSFYIPGGYFSSVWFVVGMIGAALFILIQLVLLVDFAHSWNESWVNRMEEGNPRLWYAALLSFTSAFYILSIICVGLLYTYYTKPDGCTENKFFISINLILCVVASIISIHPKIQEHQPRSGLLQSSVITLYTMYLTWSAMSNEPDRSCNPNLMSFITRITAPTLAPGNSTAVVPTPTPPSKSGSLLDSDNFIGLFVFVLCLLYSSIRTSTNSQVDKLTLSGSDSVILGDTTTSGASDEEDGQPRRAVDNEKEGVQYSYSLFHLMLCLASLYIMMTLTSWYSPDAKFQSMTSKWPAVWVKISSSWVCLLLYVWTLVAPLVLTSRDFS
What is the function of this protein?
Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm.
What are the official names of this protein?
Serine incorporator 3.
What is the protein family that this protein belongs to?
Belongs to the TDE1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=Localizes to the cell membrane, where it is efficiently incorporated into budding gammaretrovirus virions and impairs subsequent virion penetration of susceptible target cells (By similarity).
Protein: YK27_CAEEL
Sequence: MSDTTDVPENQKSPKPSGKADKRKIEEKPENSSLKRKKFEDPNKKVDPLEELPMKVPFKIVDGVRHLAPYWACYRTRTKGRWIGRKMVEVFSGEFLSTNRNYAKIACKMGRIYVNGEQMTDVDYVMRNGDRVEHWAHRHEHPIRDLPIRVISETDDLFVVEKPPSLPVHTCGQYAIHTVLGQLRVNEGRTGLRVLHRLDRATSGVLLFAKNYETDLEFKTTLKQGEWSKEYICKVDGVFPDEEQVCEQPIGPLVISMGIQCVRPDGKDAKSRFRKLWSDGTQSVVQVHIETGRTHQIRVHSQFLGHPIAGDQIYNSAVWGPTKGKNADYQKSFDELCEDVRNTHKCENWHEKPNPEFEQRMEHLAADTTPITPEAPSLTLEQRPEFDEICQKCNVESKKVPENHFQLYLHCLKYETKKWSFKTEMPDWAVQK
What are the official names of this protein?
Uncharacterized protein K07E8.7.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase RluA family.
Protein: SEC16_CANGA
Sequence: MTPEAKRKKNQKKKLRQKQKKAAEKATDLPATDQSVNISGAEDALTSNSNVSTPDYTSNFEISVTSTQEVNVDSQLSQNQNSDNFINEQKENDPQSETVFDSHEDIESEMKDNYHNDIKNTTEAITFDTAQNIIGGSIDSSNTVKSEDKINESSSKISDPDCQEDILKLELEGQPLESSCNDDKESVVEGNNENDNNDDLVNDHPTAEDGSDFFDNLASNNTEVELSSTQNSNLLTENRLESEEFGKPEKLDYPKELSYSEEVDLVEEVDHVEEVDHVEEVDHSEEEDLVEEVDHVEEVDHSEEVDHSEEVDHVEEVDHSEELLTSSVSTQTGMAENTIRHVDESNLGQQKMEERNINSDTHKDATARVSDFHANDEFETGPAAQINSLIEMNDDEQSVNDLQDESSLLQEETTFSQIPKNEVNTENQENIGSESVSKINVANENSMESAIEDLFPSMHNTNEQNPWELPQQGENVVENEVSHEENQRITETTKDDSDNIDRILCDREDKKEDSFDDLFGNNEVGDDVPWLQESMKSEEGEKHHQSSTAKEESPANVRTSDNTASQDNDTLPSESVKSNQQQNVESSSDRQQTSADTVKKFSFLEEDDDLLDDDDSFLESEEEIEELESNETVQINELTQEMSTSAESKKLNHNPYRPSSHSSINTQMDPKYNNYQTVPNSSTAPTGIVRPQQITTFLPTNNAQTNTPGTILSPIQTTNEKVKKLTEEKKKSDAYDFPINLVSSTVKKGHAKPVGVFTNQFSRNGSTPTTPKINPHSRNSSVNPAQIIPKNPYASIQQPNPVIAPTTNMINNPINMMPTARMRGNSAVSTTSGKSVGTSVATKQNPYSPQITKSPRASISQPAGIPNNSKYGPISPSTSQFNSLGQVLDSGLVHSSTTPMGSTLSPISTKLNANNQPSPQSKQYPGNSSYLPSQNDSRSKYAPAFSTGQYAGYSSHSKPAVNQPALPFPRKQSESAGDANPPINTVLPPGIRKTNVLLESQQNLRQNANYPTYAEHSHEQTNSYNVHGASNKKIVNNNALLVKQFPIFNWGSNNKVIYGIPLGQNDSVMMPTNSPLQNLRMIGAEILIKPTQLIKSFPGPLCGSKVKKSDVEQWLLTASKDADVDEEAALLLSLLKLKLSTTSTFKDMATLLYDTATLHEYLAQPLTSLNQAPNAFSLDPESQFRVLSFLQVGAHDDALRFSLEKKDYSISLLIGSLLGKDKWCEVVQRYLSEQFTAIANNSNLWAHLLPLIFQVFVGSSKTAVSRFYKNQEEANWAAENWRGIVAAVLINITDHSQPKQTASIQTPPAVVTEFLIEFGIFLKKLGMNLPASILFVIANVPLSNVPILPDSDVHFRSIGSTNNVLGAILSETYEYTISQDLKFKGYPATLPLKLFHAYCLQEEGLTSLAYKYVDYLSSATKSMTKKDAESLNLSHHLSILTNRLAGSSSSWLGKPKLSSVWGQIDKSFNKYIGGDDDLPKPATEKKVFDSYTPSSSTNSSMIDLSHSVSNFMPAQINQLSRNNLNSENKMSTVPDLTAFGEKNAFEPPTNTWTGMSLQGSPQRAVSNMKPPLSNRPNLRRIKTELPSGEDELLSMTVKQGKKSYAPDNLNRASNSSNETLKSSQSANNSVPYHQSTPNLIGMQSVEQKKSYYPSNQRAMRKSAMPTQPENLEISRNARSYEPHTKTKKVYKPNQTLEEEPPIQSYNDDVVSQNQFEEAPNLQNDQEKILQPTASPEGLSQTRISNYSPERPPLPVYSEDSKNMDPKNISDLVKEQQITDKSLEHELEQLPTENDADYKISNANEDNAINEEEREIGNGEVELNVDQSQSHLSASIPQTQNDRESTTVSISPGLGLEMDVDKEDSNAPAPKLFSEKPNPSPYAPPTVGKKGTKKTSYMPKGKTESFIAEPEISSYESSPLDMYAYSGYRPQEKEKSTSSIVEESSQISNEDAPDKSSIAARQAVELKQDEVSKKPITTKLSTPKSLPIPPSPFANPLANNNTTGVLPTENFEPVIKVSRNTTARAFTPVPPASDQYDDVVEEDSDDSDDSEDDSPMQSNNSNNGNSERNENKQNDNYSDDEMPTKKKSHDNNDAGSGWFGWLKKDTNEKKAVKAKLGNQNSFYYDEQLKRWVNKNASEEDKQQLATPAPPPPIVKRKDTEPKTKPRSISGVTPHLDTGIGSSIPPISGNAPPKPKSGPSLAAKTNGLDDLLNLTAAAPATSTRRKKKGGRGYVNVMENL
What is the function of this protein?
Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules.  Also involved in autophagy (By similarity).
What are the official names of this protein?
COPII coat assembly protein SEC16, Protein transport protein SEC16.
What is the protein family that this protein belongs to?
Belongs to the SEC16 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ENOPH_YEAS1
Sequence: MGDNYSTYLLDIEGTVCPISFVKETLFPYFTKKVPQLVQQDTRDSPVSNILSQFHIDDKEQLQAHILELVAKDVKDPILKQLQGYIWAQGYESGQIKAPVYADAIDFIKRKKRVFIYSSGSVKAQKLLFGYVQDPNAPAHDSLDLNSYIDGYFDINTSGKKTETQSYANILRDIGAKASEVLFLSDNPLELDAAAGVGIATGLASRPGNAPVPDGQKYQVYKDFETL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase, Unknown transcript 4 protein.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: DCD_CAMC5
Sequence: MGLKSDAWIRKMSHEKAMIVPFAEEQVGRGVVSYGVSSYGYDIRVGDEFKIFTNIGGTVVDPKNFDEKNVVDFKGDVCIVPPNSFALARTIEYFNMPDNVLAICLGKSTYARCGIIVNVTPFEPGFKGHITIEISNTTPLPAKIYANEGIAQVLFIEGDEPCEVTYADKKGKYQAQEGITLPRILK
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: EFTU_GRABC
Sequence: MAKAKFERNKPHCNIGTIGHVDHGKTSLTAAITKVLAETGGATFTAYDQIDKAPEERARGITISTAHVEYETGNRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLARQVGVPALVVFLNKVDMVDDPELLDLVEMEVRELLSSYQFPGDDIPIIKGSALCALEDKNPEIGRDAILKLMEAVDAYIPQPERPLDRPFLMPIEDVFSISGRGTVVTGRIERGEVKVGDEVEIVGLKATSKTTVTGVEMFRKLLDRGEAGDNIGALLRGTKREDVERGQVLAKPGSITPHTKFAAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGVVSLPEGTEMVMPGDNVSMQVELIAPIAMDEGLRFAIREGGRTVGAGVVAKISQ
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEGS_PSEPF
Sequence: MSERKALLILHGKQALNEAVRAAVENKRKQGWKLAVRLTWEAGDAQRLVEEALAAGYRQIIAGGGDGTLRDIAEALAKQPGKASLVLLPLGTANDFSRAAAISLEPAEALELLEAPAHDIDLGEVGGQIFLNMATGGFGSQVTANTSEDLKKVLGGAAYLFTGLSRFSELHAAYGELQGPDFHWRGELLALGIGNGRQAGGGHVLCPEALVDDGLLDISILPAPQELVGTLKNLLSDGFGIDNMFVRARLPWVEIKVAEGLYINLDGEPLEGESLRFAARAGALRVHLPKDSPLLSATHRISHPD
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS-like.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS_TRIV2
Sequence: MTASDIQPTEPHTPPTPHADTRLVDRTKLSKMYQHYVEVKDKYPHALLLYRVGDFFETFFQDAVTVARELELVLTSKHGGEVGRVAMTGVPHHAWERYTTQLVEKGYAVVICDQVEDASEAVGLVRREVTRILTPGTLLEEGMLKSSRNNYLAAVVITSNHWGLAYADISTGEFLTTQDSDLERLTQELMRLQPSEVLVPTNAPDLGTLLRPGETSPHLPECLPPSFCYSLRSQQPFSQAEARSTLLQRFKVRSLEGLGCDHLPLAVRAAGGLLEYVEDTQKAGQVSLQRLRTYTITDYLIVDNQTRRNLEITQTVRDGTFHGSLLWALDKTSTAMGSRALRRWLLQPLLDIKGISSRQDTIQELVTNTRLRQDLRHLLRQIYDLERLTGRASSGTANARDLVALADSLSRLPELANLVIDAHSPFLKALQKVPPILEELAQKIHAHLVESPPLHLKEGGLIRPGVNPLLDERKATVEADHQWIANLEVDERARTGIPLLKVGFNETFGYYISISRAKADQVPANYIRKQTLKNEERYITPELKEREARILTARDDLHKLEYEVFVTLREEVGEQAEAIRHLSRAVAAADVLCGLAELAVYQGYCRPEMVNGREIAIIDGRHPVVEQSLPAGFFVPNSTQLGSNEETHQLPDLIILTGPNASGKSCYLRQVGLIQLMAQIGSFVPAKSARLGICDRIFTRVGAVDDLATGQSTFMVEMNETANILNHATSRSLVLLDEIGRGTATFDGLSIAWAVAEYIATEIRSRTIFATHYHELNELAGMLPNVANYQVTVKELPDQIIFLHQVQPGGADKSYGIEAGRLAGLPTVVIQRAKQVMGQIEKHSKIAMGLQNLD
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: DAPE_SALPA
Sequence: MSCPVIELTQQLIRRPSLSPDDAGCQALMIERLRKIGFTIEHMDFGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARNERLDYCLVGEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDRGNDFFPATSMQVANIQAGTGSNNVIPGELFVQFNFRFSTELTDEIIKERVHALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: MQO_SYNSC
Sequence: MQHDGSFNPEARFDAVLVGAGIMSATLAALLHELDTQLRILLVERLEAPALESSAAVNNAGTGHAANCELNYTPIQADGTVATAKAVAINTSFERSLEFWSSLQERGDLDTSSFLHQAAHISAVWTPENIAFLRQRFSQLKELPAFARMRWSEDQSELTEWMPLVMAGRDLKQPVAATRIDRGTDVDFGSLTRAYLMPLQQSGALSVEYGTQVHDLKRLRHSDMTEADWRVVLKGPSGKKEVRAPFVFLGAGGGALPLLQRSGIPEAADFAGFPVSGLWLVCGDAQLADRQRAKVYGKAAVGAPPMSVPHLDTRWVDGKRSLLFGPFAGFSSKFLKQGSLLDLPASVRATNLLPMLQVGATNFELVQYLINQLRQSPTQRHEALQQFMPTARAEDWTLSVAGQRVQIIKRSKQGGRLQLGTEVVASGDGSLAALLGASPGASTAVTIMLEVLERCFKQRLDSDAWQQRLQALLPSIHEDPHQDPQVLNRMRERSDALLGLTA
What are the official names of this protein?
Probable malate:quinone oxidoreductase, MQO, Malate dehydrogenase [quinone].
What is the protein family that this protein belongs to?
Belongs to the MQO family.
Protein: PQQD_PSEF5
Sequence: MSFDRSKTPRWRPGYRFQYEPAQKGHVLLYPEGMIKLNDSAALIGGLIDGERDVAAIISELEIQFPGVAELGEDIEQFMEVARAQHWIELA
What is the function of this protein?
Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
What are the official names of this protein?
PqqA binding protein, Coenzyme PQQ synthesis protein D, Pyrroloquinoline quinone biosynthesis protein D.
What is the protein family that this protein belongs to?
Belongs to the PqqD family.