PharMolix/UniProtQA huggingface dataset:
Protein: LONB_PYRHO
Sequence: MLSGESEMDEERMDLGIEFETTEEIPVPERLIDQVIGQDHAVEVIKTAAKQRRHVLLIGEPGTGKSMLGQAMAELLPTEELEDILVFPNPEDENMPRIKTVPAGQGRKIVEEYRRKAKEQEGVRFYLLFFVFFIVAMAVFLSHGDPNTLLLGVFVILVALMVTANMRFKTQAMVPKLLVDNSGRKRAPFVDATGAHAGALLGDVRHDPFQCFSGEEVIIVEKGKDRKVVKLREFVEDALKEPSGEGMDGDIKVTYKDLRGEDVRILTKDGFVKLLYVNKREGKQKLRKIVNLDKDYWLAVTPDHKVFTSEGLKEAGEITEKDEIIRVPLVILDGPKIASTYGEDGKFDDYIRWKKYYEKTGNGYKRAAKELNIKESTLRWWTQGAKPNSLKMIEELEKLNLLPLTSEDSRLEKVAIILGALFSDGNIDRNFNTLSFISSERKAIERFVETLKELFGEFNYEIRDNHESLGKSILFRTWDRRIIRFFVALGAPVGNKTKVKLELPWWIKLKPSLFLAFMDGLYSGDGSVPRFARYEEGIKFNGTFEIAQLTDDVEKKLPFFEEIAWYLSFFGIKAKVRVDKTGDKYKVRLIFSQSIDNVLNFLEFIPISLSPAKREKFLREVESYLAAVPESSLAGRIEELREHFNRIKKGERRSFIETWEVVNVTYNVTTETGNLLANGLFVKNSGGLGTPAHLRVEPGMIHRAHKGVLFIDEIATLSLKMQQSLLTAMQEKKFPITGQSELSSGAMVRTEPVPCDFILVAAGNLDTIEKMHPALRSRIRGYGYEVYMRTTMPDTPENRRKLVQFVAQEVKKDGRIPHFTRDAVEEIVREAQRRAGRKGHLTLRLRDLGGVVRAAGDIAVRKGKKYVTREDVLEALKLAKPLEKQLADWYIERKKEYQVIRVEGGEIGRVNGLAIIGEQSGIVLPIEAIVAPAASKEEGKIIVTGKLGEIAKEAVLNVSAIIKRYKGEDISKYDIHVQFLQTYEGVEGDSASISVATAVISALEEIPVRQDVAMTGSLSVRGEVLPVGGVTPKIEAAIEAGIKTVIIPKSNEKDVFLSPDKRKKIKIIPVERIDEVLEVALVESEKKRELIKRVRESLPLWMEETPSGETLHEHKGGATLPLEESKA
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins.  Degrades polypeptides processively (By similarity).
What are the official names of this protein?
Archaeal Lon protease, ATP-dependent protease La homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family. Archaeal LonB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FARP_MANSE
Sequence: QDVVHSFLRF
What is the function of this protein?
Increases the force of neurally evoked contractions in the major power-producing flight muscles, the dorsal longitudinal muscles and so is likely to play a role in sustaining or promoting flight behavior patterns.
What are the official names of this protein?
FMRFamide-like neuropeptide.
What is the protein family that this protein belongs to?
Belongs to the FARP (FMRFamide related peptide) family.
What are the subcellular locations of this protein?
Secreted.
Protein: OPEP2_NPVOP
Sequence: MNTNKHVKTYMNSIVFDTAAVQAAAALQPIMETEAAQSAQVPHSSEAALQLMVETEAAQSVSAAPQEVANEILQDAGDTSARVITTTDALQVFSEAVQAIGEVIQETADGPHAIIEVKRAVFDATKMLAQLGTAVVKFYSPLFTAPERIVELVYSISLLVRIMKRIIKNDSLDKLTVDGLDSAATLLADVRSIIGDMFEVFVVNFRYAAPAEYFEAVDEMVHTVTDLALHVVKTVC
What are the official names of this protein?
OPEP-2 protein, P25.
Protein: SYE_LACLS
Sequence: MNKKIRVRYAPSPTGLLHIGNARTALFNYLFARHHGGDFIIRIEDTDRERHVEDGERSQLENLRWLGMDWDESPETHENYRQSERLPLYQKYIDQLLAEGKAYYSYKTPEELEADHAKQEAAGIPPHYINEYAGMSDDEKAAYIAERKAQNIEPVVRISVDEKAIYKWNDIVKGEIEFEGGNIGGDWVIQKRDGYPTYNFAVVVDDHDMQISHVIRGDDHIANTPKQLVVYDALGWEAPQFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYMSDAIFNFIALLGWNPGGEKEIFSREELIELFDENRLSKSPAAFDQKKLDWMDNEYIKNADFAKVFELTKPFLLAANRFDERAQELVKLYQPQMKSADEVVELTDLFYGDFPELTDEAREMLAAETTPLALSTFRAKLAELPESDFTVENIFPLFKATQKETGVKGKMLWMPIRIAASGSMHGPELPETIALLGKEKVLAHLDAALNK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_YERPE
Sequence: MAKNIQAIRGMNDYLPADTAIWQRIESILKQVLSGYGYSEIRMPIVEQTPLFKRAIGEVTDVVEKEMYTFDDRNGESLTLRPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRYERPQKGRYRQFHQLGAEVFGLPGPDIDAELILLTARWWRALGIFEHVKLELNSIGSLAARADYREALVAFLEQHVEVLDEDCKRRMYSNPLRVLDSKNPDVQQLLDDAPKLSDYLDEESKQHFAGLCELLDKASIPYTVNERLVRGLDYYNRTVFEWVTHSLGAQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNADFQVPATVDAYVISSGEGAQSAAMLLAESLRDALPTLKIMTNYGGGNVKKQFTRADKWGARVALMLGESEVAAQQVVVKDLRNGEQETLAQADVAARLALMLG
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YR327_MIMIV
Sequence: MVDVYNELGLNYDPNFEEQRNLIDVYLRIYFPKIRPEEFISILDFLNESASDAKKGIEKNKIRTVYDTIKNNLILENEPMRDIEITKKKYEKEYVKLFKENYVTQSFIRAYLLDRGKKIDLFRIFDNFILNENYPFIQYQPPDGTPRSRYNEKYLLENERKEIIMKWFENTPWGISFKVRVSDKSDYKYMAINLSDNGRIDYKIQWKEEDMQTVDDIDKTYSFVKDLIRKINRENERFGIKLKIPSDDQFKFAFINTIQKFELPDNFAINHNDLSEFSRYFFPYVALVIEPRKRQSKTKTTERDERSKFGTYLRYKRVSKYDNKTKIEHRIVFFMRNYEYNDQSLSNEISKEFNITEEQALEEINAVRERYPNIKKSRKVLKKLENIPKYKPPGIGVDIQGKTRNNYKMRIAGARDRAQLNRIITFMNILIYLYAETYLYKRPDRQRMKDLLQKLTKIARRRNKVDEIVNHETPIKSVKQMTNIDRKRLTSKTEDDQNQWTRDCQNSGEDKKRRPQQFLNVEELQKLGYVWNPKLGDINFGHYERKIMVDSNGRTDSNKKKSEVVLRAVMLPLDDSGNNYVYYTCGPEENGKHMYIGFLKSKNPYGEAKPCCFIKDQLYSKNNDKRNLFLKSIGLIQNDESEVNKIVGDQLYILQSSNKIQEGRFAFLPKYLDIFLNAMLNNERVIKNHYLVSTTTGYYFKYGTKQDEYRYLNAVGSVLDLSIEDLRNKLSSSLTKDKNQLLFTSLNNGDIRAQFGSMESYLTYINTNKYLEYPLLNDLICSPGVINKYGLNIIIFQRKIRIIRKSFEREKIREHYYIVCQNHENIEDLIDPDRETILIVKEGKNYYPIILVKKEDENTKEVSITKTFQYNSNPENIVSHIFKYYEVNCQQEFKLLIKEKSNSNLNAKETNKILISLGIKEYVPKYQMIDARFKCRYLITNAGYIIPVIPSGIVKNVNIISTVNNYLKDYTTTQKYLTDLSKLTKNKLKIKPIGVFYKDKRQKSYVISAIMTEGYDAVPIIERSMTSEYIKKEKLLTQGRPNDEDIDRDISRGKSSIVVDKRVYEVSKNKYETETYQLFRYHLSYFLNNTTEGGKFKKEIENIINSEDINKRERKLELKNVLYRMTNADLSKTFNQLISRLNKQFGGQDNVSDQSENQSENQSLESETSPIVRELNPLTQANSPISIIQEPDTIQIIPEDFVPGRRNNLRESFVNTDVDEFDYSEQINPLDEPFDYATNKEPMAESVPFPKNEKTWLSIMPDSKIIDYPSYILKNNREYCYINKNKDACNINKHCAWNNSKNLCLFNVKRIQLIDFINQVTEELIQNELRASEILRRGEYFVSNIVDYNVFTERPGERIVMASNSNLEKILSELFGKENIPRIGKKRYKFDNTQTYEQLNFDNPLKETSIWYIQNIIDNNNTVFRAFANTYYWLVHPYDEVSMRNIGYYSPLQTTLSNIYKSQVINWLLQQENQDMIQKISSYIRYNKVEDFVTKLSMDVNTISSGIVELCILSILYETIIYVNDEYFNVIYVLHPTQGIVYDYKKSKNKFTNEKYQSYKKVIDIRFRYSSNSNYPDYIDALYPKKNN
What are the official names of this protein?
Uncharacterized protein R327.
What are the subcellular locations of this protein?
Virion.
Protein: EX7S_SINMW
Sequence: MNNTAQQDVSALSFEQAVEELERIVSALERGDVALDKSIEIYERGEALKKHCEALLKAAEDRIEKIRLDRAGRPQGVEPLDAE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPB1_CAEJA
Sequence: MQSQLKACGDAPAPSCSLHHRRTISKKPSNGGNSGGGGGGVNSAYLATDVTTLDINAMFQSKKMKRHGAGVTAPSTPANYLGASAGAGQANPAHFNFPSYLNPASFYPNVDLLGGSSEHLPPLMSVPAYKPTSMLHGFSDAASAMDFAQLTEELNALQNLSASFPNSTPNAFQSLFATDSPSSFLTSSAVSSHLAKPSPLTANSVRGAGGRKNRMVEVKMINERPVVIVSDPQAASASARSQIVHLNRNVLGVLKGLEASKKRSISAEPLYSRKVFIGGLPIDVTEEEVWATFGWFGKVLVDWPRRPEHGGRGDFYEMDMGRRNSRSVSGYVFLVFQDEKAVQELVNACELYENKYYLQLSSPTMADKAVQVRAWRLSDIDYFCDENASVDHRRTVFIGGVPRPTRASDLAYCLQQHYGKVSYVGIDIDPELKYPKGAARVTFATAQSFVRAISGRFVQVTHADTNKRVEIKPYVMEDQHCDECQGKLCKHNYAPYFCGDSSCLQYYCEACWDRMHYAMCDNRADHRPMVRTGDQTRILPRPPHHSTSHYHHRSTPSHHHNHTHQNVTSSLLEHAPHLQNTSIISRIVNRNNQNNNSANSTPPQMKQFSAIPTAIGY
What is the function of this protein?
Cytoplasmic polyadenylation element binding protein that binds to and regulates the translation of specific mRNAs.  Essential for progression through meiosis.  Involved in spermatogenesis (By similarity).
What are the official names of this protein?
Cytoplasmic polyadenylation element-binding protein 1.
Protein: SWC5_CANGA
Sequence: MEETDIAKLSEEEYNEEEDEDFDPTKGTAVAGAEVSDGEDDDEDDEDDSRVKDSYSHIVSESGGLVKTRRARQQEEEFKRKNKYEGIVEAAISEKVGSIWEDLKKESLSRLHNKENDSVISESSKLKKDNHVAGEEMVTIERVYKFAGETIREKKTVPISSAEAVEYLNNLKFRKSTDQAGSTKRKLEEIDVKENNNTNEDTSESGIDRKKLRRPLKRPPFLEQIISGALKPKLSTLEKSKLDWATYVDKEGINDELSAHNKDGYLAKQDFLNKVDSVKENEYKELRRKEMMIRLQETK
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Involved in chromosome stability (By similarity).
What are the official names of this protein?
SWR1-complex protein 5.
What is the protein family that this protein belongs to?
Belongs to the SWC5 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TUAC_BACSU
Sequence: MKILWITSVYPSSMKPGEGVFHETQVQELQKLGLDITVICPRPFHSAPVRMLKKTYRKKDVRPEYEIRKGIPVYRPFYRAVPGQLKWAQPHRRIASAVLKTMKQRDLYPDLIHAHFAMPSGGAAAVVSESAQIPYVLTLHGSDVNVYPHYSKGAFKAFKRAVGSASVVLAVSHKLQEEAKKLSGFDSSVLPIGIQLSRFQGNEETKEEIRKRLGLPLDQRLAVYVGRLVREKGIFELSEAIESLQDSPKAVFVGDGPAKSTLTQKGHIVTGQVPNHQVRDYLLAADLFVLPSYSEGMPTVVIEALALRVPVICTDVGGVSSLFGKHQHLLIKPKSAQALAEAITRYEHEQIWKPEVADDLYETVQAQFDAGKNAKALHHQYQTVTKTSV
What are the official names of this protein?
Putative teichuronic acid biosynthesis glycosyltransferase TuaC.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: TSAD_PSYA2
Sequence: MKVLGLETSCDETGLAIFDSEQINSENKGLLGQVLYSQIELHALYGGVVPELASRDHIRKLVPLFNELLAQCNISKDEIDAIAYTKGPGLIGALMTGALFGRSLAYGLDIPAIGIHHMEGHLLAPLMGLNPPAFPFVSLLVSGGHTLLIAAHGIGQYEILGESIDDAAGECFDKAAKMLGLPYPGGPNIAKLAENGNPNAYSLPRPMLHRGLDFSFSGMKTAVHNLIKDTDGSGNGSDSDPQVRADIAASFQHAVVDTLVKKCVKALKQVDMSRLVIAGGVSANSHLRETLERELAKINATVHYAPPALCTDNGAMIAYAGYERLQAGQSDDLAVSCVPRWPMTELPAV
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXD12_HETFR
Sequence: MCEHNLLNSGYVGSLLNFTSPEPFYFANLRPNGTQLATLSPALSYTRRDVCSLPWTSSPCASPPQSRAFSGYSQSYLSNSVSISINRHVSDKAAAGEEPNKYYFQDSSRKVEERCRHNQSYPSDASIPSSVNINPAKYEYPNVETSLHGSSLHNQGFELNSNSPTVNDGIKQSVSLSMSLQSSVTPVCNRSSDGLPWCPTQVRSRRKRKPYTKQQIAELENEFLANEFINRQKRKELSDRLNLSDQQVKIWFQNRRMKKKRLVMREQTLSLF
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-D12.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYRC_BACC7
Sequence: MNYLFKDGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIDVNGKLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICAMPNTRPVPDCREHMEDLQNRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSADPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV
What is the function of this protein?
Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
What are the official names of this protein?
Dihydroorotase, DHOase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
Protein: FIS_ECOBW
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: CCSA_CRUWA
Sequence: MIFSILEHILTHISFSVVSIVLTIYFLTLLVNLDEIIGFFDSLDKGIIITFFGITGLLFTRWIYSGHFPLSNLYESLIFLSWAFSIIHMVSYFNKKQQNHLNAITAPSAIFIQGFATSGLLNKMPQSAILVPALQSQWLMMHVSLMILGYGALLCGSLLSIALLVITFRKVGPTFWKKNIKKNFLLNELFSFDVLYYINERNSILLQQNITFSFSKNYYRYQLIQQLDYWSFRIISLGFIFLTVGILSGAVWANETWGSYWNWDPKETWAFITWTIFAIYLHIKTNRNVRGINSAIVASIGFLLIWICYFGVILLGIGLHSYGSFTSN
What is the function of this protein?
Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment.
What are the official names of this protein?
Cytochrome c biogenesis protein CcsA.
What is the protein family that this protein belongs to?
Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RS7_ACIC5
Sequence: MPRKGHIAKREVAPDPVYGSTLVTKFVNSMMWGGKKSTAQGIFYSAMTNLEQKGGDEAIKLFKKAVENCKPLLEVKTRRVGGANYQVPVEVNPERRTSLAIRWLVSYGRARGEKGMIEKLTNELLDAANGRGAAMKKKEDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: CCA_POLNA
Sequence: MKIYMVGGAVRDKLLGLPVTDHDWVVVGATPEALTAQGFLPVGKDFPVFLHPQTREEYALARTERNSARGYRGFEVYAAPEVTLEQDLARRDLTINSIAAPAHPDSAKGLFEPDFDALVDPYGGQRDLQAKVLRHVTDAFREDPVRILRLARFAARFADFSIAPETLAMMWEMVTDGEVDGLVPERVWQELARGLMEDKPSRMFDALRACGALQHLLPEVERLWGVAQSAQYHPEIDTGIHLMMVLDMAAQLGAPLPVRFACLCHDLGKGTTPADVLPRHIGHEERSAKLLKDVCQRLRVPSECREIADVVAREHGNIHRSGEFSPAAVVRLLERCDAFRKPRRFADILLACECDARGRLGFEQTPYPQRPRLLQLLAAAQSVATDKVAAEAMAAGQSGPKIGEWIHQARVEAVRQSAAAAPAP
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: MENC_MYCTA
Sequence: MIPVLPPLEALLDRLYVVALPMRVRFRGITTREVALIEGPAGWGEFGAFVEYQSAQACAWLASAIETAYCAPPPVRRDRVPINATVPAVAAAQVGEVLARFPGARTAKVKVAEPGQSLADDIERVNAVRELVPMVRVDANGGWGVAEAVAAAAALTADGPLEYLEQPCATVAELAELRRRVDVPIAADESIRKAEDPLAVVRAQAADIAVLKVAPLGGISALLDIAARIAVPVVVSSALDSAVGIAAGLTAAAALPELDHACGLGTGGLFEEDVAEPAAPVDGFLAVARTTPDPARLQALGAPPQRRQWWIDRVKACYSLLVPSFG
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: ADA10_XENLA
Sequence: MGLLRLVFLLSWAASAGGLYGNPLNKYIRHYEGLSYNVDSLHQKHQRAKRAVSQEDQFVHLDFQAHGRQFNLRMKKDTSLFSPDFKLEVGGETVNYDTSHIYTGQLFGEQGTLSHGSVVDGKSKGLLKPLKAHSYVEPSERFFKDQAVPFHSVMYHEDDIKYPHKYGSEGGCADSSVFKRMKEYQMSVQEEPEKHDHKEDHEDSGPVILRKKRAAQAEKNTCQLFIQTDHLFYKRYGETREAVIAQISSHVKAIDTIYQSTDFSGIRNISFMVKRIRINVTSDEKDPTNPFRFPNIGVEKFLELNSEQNHDDYCLAYVFTDRDFDDGVLGLAWVGAPSGSSGGICERNKLYSDGKKKSLNTGIITVQNYGSHVPPKVSHITFAHEVGHNFGSPHDSGNECTPGEAKNLGFKENGNFIMYARTTSGDKLNNNKFSICSVRNISQVLDKKENSCFVESGQPICGNGLVEPGEQCDCGYSDQCKDECCYDANQPENLKCTLKPGKQCSPSQGPCCTTDCTFKRASENCREESDCAKMGTCNGNSAQCPPSEPRENLTECNRATQVCIKGQCSGSICERYDLEECTCGSTDEKDDKELCHVCCMEKMKPHTCASTGSEAWKAYFKGKTITLQPGSPCNEFKGYCDVFMRCRLVDADGPLARLKKAIFNPELYENIAEWIVAHWWAVLLMGIALIMLMAGFIKICSVHTPSSNPKLPPPKPLPGTLKRRRPPQTTQQPSRQRPRENYQMGHMRH
What is the function of this protein?
Controls the proteolytic processing of Notch and mediates lateral inhibition during neurogenesis.
What are the official names of this protein?
Disintegrin and metalloproteinase domain-containing protein 10, ADAM 10, Kuzbanian protein homolog, xKuz.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DDI2_HUMAN
Sequence: MLLTVYCVRRDLSEVTFSLQVDADFELHNFRALCELESGIPAAESQIVYAERPLTDNHRSLASYGLKDGDVVILRQKENADPRPPVQFPNLPRIDFSSIAVPGTSSPRQRQPPGTQQSHSSPGEITSSPQGLDNPALLRDMLLANPHELSLLKERNPPLAEALLSGDLEKFSRVLVEQQQDRARREQERIRLFSADPFDLEAQAKIEEDIRQQNIEENMTIAMEEAPESFGQVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAGIAKGVGTQKIIGRVHLAQVQIEGDFLPCSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSQTTFLPEGELPECARLAYGAGREDVRPEEIADQELAEALQKSAEDAERQKP
What is the function of this protein?
Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane (PubMed:27676298, PubMed:27528193).  Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1 (PubMed:27528193).  Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2 (Probable).  Required, with DDI1, for cellular survival following replication stress.  Together or redudantly with DDI1, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (PubMed:29290612).
What are the official names of this protein?
Protein DDI1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the DDI1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Chromosome.
Protein: GFRA2_CHICK
Sequence: MILANAFCIVLFVDETLRSLAAPPSPPGQDLQGWRVPVDCIRANKLCAAEGSCSSRYRTLRQCLAGRDRNTMLANKECQAALEVLQESPLYDCRCKRGMRKEIQCLQVYWSIHLGLAEGEEFYEASPYEPITSRLSDIFRLASIFSGMDPATNSKSNHCLDAAKACNLNDNCKRLRSGYISTCSKEISATEHCSRRKCHKALRQFFDNVPSEYTYRLLFCSCKDQACAEPRRQTIVPFCSYEDKEKPNCLDLRNVCRADHLCRSRLADFHANCQASFQSLTSCPGDNYQACLGSYTGLIGFDMTPNYVDASTTSITISPWCSCKGSGNLEEECEKFLRDFTENPCLRNAIQAFGNGTDVNLSPKNPSPPITMLPKVEKSPALPDDINDSNTMYDTSIITTCTSIQEHGQKLNKSKEQSLCYSETQLTTDTMPDQKTFVDQKAAGSRHRAARILPAVPIVLLKLLL
What is the function of this protein?
Receptor for neurturin.  Mediates the NRTN-induced autophosphorylation and activation of the RET receptor.  Also able to mediate GDNF signaling through the RET tyrosine kinase receptor (By similarity).
What are the official names of this protein?
GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, GDNFR-beta, Neurturin receptor alpha, NRTNR-alpha, NTNR-alpha.
What is the protein family that this protein belongs to?
Belongs to the GDNFR family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor.
Protein: CRCB_BURP6
Sequence: MFYSIVAIFVGAGLGALLRWFLSIGLNALLPEVPLGTLASNLIGGYLIGIAVVAFATRAGLPPEWRLFVITGFMGGLTTFSTYSVEVMTHAVQGEFGWALAVAALHLIGSFTLTGLGMWTARAWLAPA
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YBAB_ECOBW
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: LEUC_HALVD
Sequence: MSEGTLYDKVWEEHTVSELPTGQTQLFCGLHLIHEVTSPQAFGMLQERDLEVAYPNRTHATVDHIVPTSDQSRPFRDDAAEEMMAELEQNVREAGINFSDPTSGEQGIVHVIGPEKGLTQPGMTIVCGDSHTSTHGAFGALAFGIGTSQIRDVLATQTVAMEKKKVRKIEVTGELGPGVEAKDVILEIIRRLGTEGGVGYVYEYAGEAIEDLDMEGRMSICNMSIEGGARAGYVNPDETTYEWLKETEYFQENPERFDELKPYWESIRSDEDAEYDDVVTIDGSELEPVVTWGTTPGQGVGITQPIPAPEDLPEEKQETARMAQEHMGVTPGETMEGYEIDVAFLGSCTNARLPDLRRAAGVVKGRQVADSVRAMVVPGSQRVKAAAEAEGLDEVFKEAGFEWREAGCSMCLGMNEDQLEGDEASASSSNRNFIGRQGSKDGRTVLMNPRMVAAAAVTGEVTDVRELKEVTTV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CLPP_WIGBR
Sequence: MNLIPTVVEKNARGERSYDIFSRLLKERIIFVTGKIEDYMANLIIAQMIFLESEDPEKDIFLYINSPGGVVTSGMSIYDTMQFIKCEVSTLCIGQSSSMAALILASGEKGKRFSLPNARIMIHQPLGGSQGQATDIAIHTTEILKIKKCMIELLSKHTGQSAEIISKDTERDRFFSGSEAVIYGLIDKVITCRK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1475_LISMF
Sequence: MPKILVDADACPVKAEIKQVAEHFQLDVIFVASFNHYSVNTNGENWIFVDTGKESADMRMMNLAKKGDIIVTQDIGLASILLAKGTFVFSNRGELYREEEMSLMLDIRYRHAKDRQQGKYSKGPKAMSDQDRSLFKDRLTTFLQNK
What are the official names of this protein?
UPF0178 protein LMOf2365_1475.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: KN1_ORYSJ
Sequence: MSNVTVCVRFRPLSHKERKTNGDKVCFKRLDSESFVFKDEREEDVIFSFDRVFYEDAEQSDVYNFLAVPIVADAISGINGTIITYGQTGAGKTYSMEGPSILHCNKQKTGLVQRVVDELFQSLQSSESMAMWSVKLSMVEIYLEKVRDLLDLSKDNLQIKESKTQGIYISGATEVSIQNSSDALECLSEGIANRAVGETQMNLASSRSHCLYIFSVQQGSTSDERVRGGKIILVDLAGSEKVEKTGAEGRVLDEAKTINKSLSVLGNVVNALTTGKPNHVPYRDSKLTRILQDALGGNSRAALLCCCSPSASNAPESLSTVRFGTRTKLIKTTPKSISPEVDSIKKPIPDSHGQNDLRDRILNKLRLSLKEEDVDLLEELFVQEGIIFDPNYSVADIDSACQDAASQEVSLLTQAVEELKETVEELTDENERLRGELELAQEAAAAAAAARADGALLGFVPAVAISSLLRPFGFVPD
What is the function of this protein?
Kinesin-like motor protein that exhibits microtubule-stimulated ATPase activity.  Plays an essential role in male meiotic chromosomal dynamics, male gametogenesis and anther dehiscence.  May play a minor and nonessential role in regulating meiotic spindle formation.
What are the official names of this protein?
Kinesin-like protein KIN-1, Kinesin-1-like protein PSS1, Pollen semi-sterility protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIN-1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.