PharMolix/UniProtQA huggingface dataset:
Protein: NUOD_RICBR
Sequence: MTNNTKSITLNLGPQHPATHGVLRLILEMDGEVVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEHAFALAAESLLECEIPRRAQFIRVLFSELTRILNHTLNIGSQALDVGATTPLLWLFEEREKIMEFYERVSGSRMHSNYFRPGGVAEDLPDGLLEDIDKFIQQFPPKLQDIENLLNENRLWKQRLVDIGVVSQKEAMDWGFSGPMLRGSGIAWDLRKSNPYDVYAEMDFEVPIGKNGDCYDRYLVRMLEMYESVKIIKQCIEKMPQGPVKTDDPKLTPPTRAKMKESMEAMIHHFKLYTEGYDVPAGEIYKAVEAPKGEFGVYLYSTGGNRPYRCRIKAPGFAHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NO66_DROYA
Sequence: MHKASTSSANRANFQGNHKTQKSPNNGKAKAKKSPNTDINVADVEMLLNPRSNLTKEQKERRKMMEGFVTKTFERAENESDGSDIDTSASTSNKGKSKAARPTDRKRRLQAEDSPPADANNNNTKNGKDGKVSKESASTQGASATKRKPPRSQGLEHTSPIQVDGEALACPLVRKSLPAAGASGASGPAKSCPLPEKRKSLPAGAAKSKSQVIKQEALEEASNEAQLLALPIETHKTDSIEEGRRVLQWLLNPIKVNHFFDDFWEHTAFVVQRKNPHYYSKLISFKMIDEMLVRHRLDFTINVDVTTYKNGKRETLNPEGRALPPVVWGLYSEGCSIRILNPSTYLVGLRQVCSIMQEFFHCLVGANVYLTPPNSQGFAPHYDDIEAFVIQVEGRKRWRLYEPPSGSDQLCRNSSSNFDQEQLGEPILDEVLEAGDLLYFPRGTVHQAITEEEQHSLHITLSVYQQQAYVNLLEKLMPIVLKKAIKQSVALRRGLPLHTFHVLGEAQRANRSDSRNQLVENVQKLVTKHLMPSAQDIDEAVDQLAKKFQHEALPPIILPEEQVRTVFGSRSTADEQGNAICDYEFDTKTSVRLLRANILRLVTEEDGSVRIYHHVDNGFEYCKYEPIFMEILPEEAAAVELLISAYPYYLTVGQMPLDSAARKVEVVTALWERGLLMTEKPFK
What is the function of this protein?
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.  Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code (By similarity).
What are the official names of this protein?
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, Histone lysine demethylase NO66.
What is the protein family that this protein belongs to?
Belongs to the ROX family. NO66 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SDH32_ORYSJ
Sequence: MEKYQSKARFAPLSDAPFALRGALGSSNSSFNNIDHLRQSSSSGQARSYTSSPLGALRPKMFPSGNRLLHTSRPLSAPVANRPLSPHLPLKKPQLSATFSISHRIFGAALGAVIISIPLATKFSLMFDV
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH).
What are the official names of this protein?
Succinate dehydrogenase subunit 3-2, mitochondrial.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: SIT2_ASPFU
Sequence: MGLFGSFGARNKATPQVPPGAVAKAPEGTPKGPETNDQPDMDSSRLSLEARNEKEIEQHPNQVTADAHLGVQKVEAAALVWSKKAVWATYAWIWVCFFLLALQSGISGNVINNAYSGFMSAPQISTANILSSIIGGVLKLPIAKILNLWGRAEGFLVFVGVYTIGLIILAACNGPDSYAAGYVLFWIGYDAIYLILDVFVADTSGLRNRAFTFAFASTPFICTAFTAPLAASSFLRMTTWRWAYGAFAIIMPVALAPLAVVFKRYQLKAEKMGLYVRQPSGRTWAQSVAHYIHEFDIIGAFLLMAAWVLLLLPFSLASNGRAEYKSAAFIAMVIIGFCLFFAFAAWEKWFARVHFINYELLKQRTVLGACVMAATLYFSFYCWDLYFYNFCTVVYNLNAAMTGYMTQIYNVGSCFWGVVFGLWVRWTKHFKHTCLFFGLPLMILGAGLMIHFRGQSDDIGYVIMCQIFIAFGGGTLVIGEQMAVMASANREGVPMMLSFIGLFSSLGGAIGYAVAAAIYTNVFPGALESRLPADLKSNATSIYMGGYTVQQTYPMGSAARDAINYAWGRSQRFGAVAATCILILGIPAIAVWKNYNVNKHQNKGVMI
What is the function of this protein?
Major facilitator transporter involved in ferrichrome (FC) uptake (PubMed:26929401).
What are the official names of this protein?
Siderochrome iron transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIPL_FELCA
Sequence: MESKTLFLMALGIWLQSLTTTRGWVAADDRITGGRDFIDIESKFALRTPEDIAEDTCHLIPGVTESVANCHFNHTSKTFVVIHGWTVTGMYESWVPKLVAAPYKREPDSNVIVVDWLSRAQQHYPVSAGYTKLVGKDVAKFINWMAEEFHYPLDNVHLLGYSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPGRSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFIDSLLNEENPSKAYRCNSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPYKVFHYQVKIHFSGTESDTQTNQVFEISLYGTVAESENIPFTLPEISANKTYSFLIYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFTIEKIRVKAGETQKKVIFCSREKVSHLQKGKASVVFVKCHDKSLNKKSG
What is the function of this protein?
Key enzyme in triglyceride metabolism (By similarity).  Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (PubMed:8636438).  Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (By similarity).  Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity).  Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity).
What are the official names of this protein?
Lipoprotein lipase, LPL, Phospholipase A1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Extracellular side. Secreted. Secreted, extracellular space, extracellular matrix. Note=Newly synthesized LPL binds to cell surface heparan proteoglycans and is then released by heparanase. Subsequently, it becomes attached to heparan proteoglycan on endothelial cells. Locates to the plasma membrane of microvilli of hepatocytes with triglyceride-rich lipoproteins (TRL). Some of the bound LPL is then internalized and located inside non- coated endocytic vesicles.
Protein: VSPHA_HYDHA
Sequence: MPLIRVLASLLILQLSYGKSLDNGAKAITSLDRIIGGFECNPSEHRSLVYLYNSAGFFCSGTLLNHEWVLTAAHCNREDIQIRLGVHNVHVHYEDEQIRVPKEKLCCLSTNNCTQFSQDIMLIRLNSPVNYSEHIAPLSLPSNPPSMGSVCCVMGWGTITSPEVTYPEVPHCVDINILHIPVCQAAYPTMSGKNILCAGILEGGKDSCKGDSGGPLICNGQIQGIVSWGRFPCAQFLEPGIYTKVFDYKDWIEGIIAGNSNVICP
What is the function of this protein?
Serine protein with fibrinolytic and fibrinogenolytic activities.  Degrades Bbeta-chain (FGB) of fibrinogen first and then the Aalpha-chain (FGA).  Gamma-chain (FGG) are also digested on prolonged incubation.  In vitro, it cleaves high molecular weight (HMW) kininogen (KNG) releasing bradykinin that promotes vasodilation.  In vitro and in vivo, it cleaves angiotensin-2 (AGT).  This explains the reduction of blood pressure in hypertensive rats.  Has also antithrombotic effects on thrombosis animal models.
What are the official names of this protein?
Serine protease harobin, Fibrin(ogen)olytic enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GPA1_SPOS1
Sequence: MGCGMSVEEKEGKARNEEIENQLKRDRMQQRNEIKMLLLGAGESGKSTILKQMKLIHEGGYSRDERESFKEIIYSNTVQSMRVILEAMESLELPLEDQRMEYHVQTIFMQPAQIEGEVLPPEVGNAIEALWKDRGVQECFKRSREYQLNDSARYYFDNIARIAAPDYMPDDQDVLRSRVKTTGITETTFIIGDLTYRMFDVGGQRSERKKWIHCFENVTTILFLVAISEYDQLLFEDETVNRMQEALTLFDSICNSRWFIKTSIILFLNKIDRFKEKLPISPMKNYFPDYEGGDDYAAACDYILNRFVNLNQHESKQIYTHFTCATDTTQIRFVMAAVNDIIIQENLRLCGLI
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
What are the official names of this protein?
Guanine nucleotide-binding protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: AEP3_YEAST
Sequence: MNTLRCLTQALSKSGREAPKLYQKVIFPGLFREGIPIANVKKVDEKIIDSPTSTSVNGEAKKIVRHGVKYEREQVKEYLSSLPTLTLSRKQIRDDYDEERAKRMYMFSKQTNSSNKFQKLLTAKSQEFTRELLTLLIDCTSNEKNSGPERFTRKFLKFSNDEIPPLPDFSKNPQLFENYIGILSHTKFNFRSSSKLNGIVRKMLRHLLHPTNKTTLPLRSAQVYNDSIYFFSEHFDFASCREIFAQMKAEGTKPNTITFNLLLRNVVKNSHIRKTKHPDDEVLFYLRSMRNHGVFADVITWTTCYNFLRDEVSRQLYIVQMGEHLGNFNVNFVYTVLRNGDYRAEDCLKVLAANSLPISRKTFYLCIERLLNEEQLETASKLLDYGFQHLKSNFKLDSEAMNHFMRVFANKGRSDLAFLCYNTCRKIYKIKPDSQTFEMLFKALVRNGNTKNFGAVLQYIKDLKVSEGFGLRTSYWRTKADSIFKFGSPNTLSEKSIEKARKLLGNLIASEGEFSWKIWKESDSSQKKILRFLGCIPTTLRCTNTAQDHQKPTNLPSNISQKKREYRNRVKAIATKAALEKRMAYIKDNDVAFKKELVKRRIVGEV
What is the function of this protein?
Required for respiration.  Stabilizes the mitochondrial bicistronic mRNA encoding ATP6 and ATP8, 2 subunits of the proton-translocating ATP synthase.
What are the official names of this protein?
ATPase expression protein 3.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: MEGL_STRAW
Sequence: MDDGRGAGGFGGGPAVRALDTEAVHAGRDDLARQGLHAAPIDLSTTYPSYDSRAEAARIDAFAADGAEPAGPPVYGRLGNPTVARFETALARLEGTDSAVAFASGMAALSAVLLVRNAMGLRHVVAVRPLYGCSDHLLTAGLLGSEVTWVDPAGVADALRPDTGLVMVESPANPTLAELDLRALAHACGSVPLLADNTFATPVLQRPAEHGARLVLHSATKYLGGHGDVMAGVVACDEEFARGLRQIRFATGGVLHPLAGYLLLRGLSTLPIRVRAASSNAAELARRLAADPRVARVHYPRIGGAMIAFEVYGDPHEVIAGVRLITPAVSLGSVDSLIQHPASISHRIVDAADRRGAGVSDRLLRLSVGLEDVEDLWADLDGALGTDRLPETAGAGREPSRTALRLPERAADR
What is the function of this protein?
Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia.  Is probably involved in L-methionine catabolism.  Is also able to catalyze the alpha,gamma-elimination of L-homocysteine, and, to a lesser extent, the alpha,beta-elimination of L-cysteine.
What are the official names of this protein?
L-methionine gamma-lyase, MGL, Homocysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the trans-sulfuration enzymes family.
Protein: MIAB_PECAS
Sequence: MTKKLHIKTWGCQMNEYDSSKMADLLGSTHGYELTEIAEEADVLLLNTCSIREKAQEKVFHQLGRWKALKDLNPNLIIGVGGCVASQEGAHIRERAHYVDVIFGPQTLHRLPEMINHVQGTRSPIVDISFPEIEKFDRLPEPRADGPTAFVSIMEGCNKYCTFCVVPYTRGEEVSRPCDDVLFEIAQLAAQGVREVNLLGQNVNAYRGETYDGEICSFAELLRLVAAIDGIDRVRFTTSHPIEFTDDIISVYEDTPELVSFLHLPVQSGSDRVLTMMKRRHTALEYKAIIRKLHNARPGILISSDFIIGFPGETQADFEQTMKLIADVNFDMSYSFVYSARPGTPAADMVDDVLEEEKKQRLYLLQDRITKQAMRFSRLMLGTVQRILVEGTSRKSVMELSGRTENNRVVNFEGTPDMIGKFVDVEIVDVYTNSLRGIVVRTEDQMDLRVHESPSSVIARTRKENEIGVGFYQP
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQJK_ECOLI
Sequence: MSSKVERERRKAQLLSQIQQQRLDLSASRREWLETTGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG
What are the official names of this protein?
Uncharacterized protein YqjK.
Protein: DTX29_ARATH
Sequence: MAKDKDITETLLTAAEERSDLPFLSVDDIPPITTVGGFVREFNVETKKLWYLAGPAIFTSVNQYSLGAITQVFAGHISTIALAAVSVENSVVAGFSFGIMLGMGSALETLCGQAFGAGKLSMLGVYLQRSWVILNVTALILSLLYIFAAPILASIGQTAAISSAAGIFSIYMIPQIFAYAINFPTAKFLQSQSKIMVMAVISAVALVIHVPLTWFVIVKLQWGMPGLAVVLNASWCFIDMAQLVYIFSGTCGEAWSGFSWEAFHNLWSFVRLSLASAVMLCLEVWYFMAIILFAGYLKNAEISVAALSICMNILGWTAMIAIGMNTAVSVRVSNELGANHPRTAKFSLLVAVITSTLIGFIVSMILLIFRDQYPSLFVKDEKVIILVKELTPILALSIVINNVQPVLSGVAVGAGWQAVVAYVNIACYYVFGIPFGLLLGYKLNYGVMGIWCGMLTGTVVQTIVLTWMICKTNWDTEASMAEDRIREWGGEVSEIKQLIN
What are the official names of this protein?
Protein DETOXIFICATION 29, AtDTX29, Multidrug and toxic compound extrusion protein 29, MATE protein 29.
What is the protein family that this protein belongs to?
Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: ANKK1_MOUSE
Sequence: MVPHRARRLLNPMAVGPLAQQLGSLTVFTRDDFEEEWHLVASGGFSKVFQARHKRWRTQYAIKCSPCLQKETTSSEVTCLFEEAVKMEKIKFQHIVSIYGVCKQPLGIVMEFMASGSLEKTLPTHSLCWPLKLRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDNNMHVKISDFGLSKWMEQSTQKQYIERSALRGTLSYIPPEMFLENNKAPGPEYDVYSFAIVIWEILTQKKPYAGLNMMTIIIRVAAGMRPSLQDVSDEWPEEVHQMVNLMKRCWDQDPKKRPCFLNVAVETDMLLSLFQSPMTDPGCEALTQKVSCKPSLSQPHKVSKEVNQEIADSVSSDSLKWILQLSDSKSLVASDVYENRVTPLHFLVAGGSLEQVRLLLSHDVDVDCQTASGYTPLLIATQDQQPDLCALLLAHGADTNLADEDGWAPLHFAAQNGDDHTARLLLDHGALVNAREHEGWTPLHLAAQNNFENVARLLVSRQADLSPHEAEGKTPLHVAAYFGHIGLVKLLSGQGAELDAQQRNLRTPLHLAVERGKVRAIQHLLKCGALPDALDHSGYSPLHIAAARGKDLIFKMLLRYGASLELRTQQGWTPLHLATYKGHLEIIHQLAKSHVDLDALGSMQWTPLHLAAFQGEEGVMLALLQCGANPNAAEQSGWTPLHLAVHKGTFLGITHLLEYGADIHACNKVGWTPAHLAALKGNTAILKVLVKAAAQVDVKGGVSCTPLQLAIHSPK
What are the official names of this protein?
Ankyrin repeat and protein kinase domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
Protein: ALAA_ECOLI
Sequence: MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSLSKFARFLSGYHQL
What is the function of this protein?
Involved in the biosynthesis of alanine.  Catalyzes the transamination of pyruvate by glutamate, leading to the formation of L-alanine and 2-oxoglutarate.  Is also able to catalyze the reverse reaction.
What are the official names of this protein?
Glutamate-pyruvate aminotransferase AlaA.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CPFC_MYCSK
Sequence: MLFDALLVLSFGGPEGPDQVMPFLENVTRGRGIPRERLASVAEHYLHFGGVSPINGINRALIAEIEAELGDRGETLPVYFGNRNWDPYVEDAVTAMRDDGVRRAAVFATSAWGGYSSCTQYNEDIARGRAAAGDGAPQLVKLRHYFDHPLLVEMFAESISVAAQSLPADVRDEARLVFTAHSIPVAADDRHGPNLYSRQVAYATRLVAAAAGYSEFDQVWQSRSGPPRIPWLEPDIGDHVTALAERGTKAVIICPIGFVADHIEVVWDLDSEVREQAADLGIAMARARTPNADRRYARLALDLVDELRGDRDPLRVAGVDPAPGCGYSVDGTTCADSPRCVARITG
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATF_ARCFU
Sequence: MKKLAVVGDPDFTIGFMLAGISDIYEVTSDEEIVKAVEDVLKRDDVGVVIIKQEYLKKLPPVLRREIDEKVEPTFVSVGGTGGVEEIREKIRKAIGVDLWK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type ATP synthase subunit F, V-ATPase subunit F.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase F subunit family.
Protein: GPDA_AERHH
Sequence: MADQIAISVLGAGSYGSALAISLARNGHPTLLWGHDPAHVAELEQDRCNKAFLPDVPFPADLQLTADLQQAVQAAPVLLLVVPSHVFGQVLAQVKPFLRPDTRIAWATKGLEPDSGRLLQDVAREVLGDEMPLAVISGPTFAKELAAGLPTAISVASTHDDFADDLSLLLHCGRSFRVYTNPDFIGLQLGGAVKNVIAIGAGLSDGLGFGANARTALITRGLVEMQRLGAALGADAKTFMGMAGLGDLVLTCTDNQSRNRRFGLALGAGKDVNTAMAEIGQVVEGYRNTKEVHLLAARCGVEMPICEQIFKVLYEGKNPKEAAIALLSRDKKDE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAC_ECOLI
Sequence: MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALGDLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDTPYIARPGNINAWDNEDFVKAVKATGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRLSQAGAQLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK
What are the official names of this protein?
Probable hydrolase YcaC.
Protein: GATB_NEOFI
Sequence: MLQQWLRQSPGAARFLRGSCCRGPQSGSLRHSPLPTAPHRCIRSLQTSATESKEHIPLRKQLKQNAKALKAQKRQKRESEEASRQKWELTVGIEIHAQLNTETKLFSRASTSNTDTPNSNVALFDLAFPGSQPEFQATTLLPALRAAIALNCDIQPVSRFDRKHYFYHDQPAGYQITQYYAPFAKNGYVDLFPHDGIAPEDGDHVRIGIKQIQLEQDTAKSQEYPPSTQLLDFNRVSHPLIEIITMPQIHNPATAAACVRKIQAILQSCSAVTTGMELGGLRADVNVSIRRRDEAPGTHQYGGIGGLGQRTEIKNLSSFKAVEDAVIAEKNRQIAVLESGGVIEGETRGWTIGSTETRKLRGKEGEVDYRYMPDPDLPPLIISHDLVSGLRDSLPTPPDQLIEMLAGPEYGLSIEDAKPLIELDDGARLEYYQDVVDILRDLQQDQDAKSRAGLARMAGNWVLHELGGLCAKADLAWDAQRVPAETLAQIIDQLQRKRITGATAKQVLAMVFDGDRRPVPQLLEAENLLLRPLSRDEYIALAEAAISQNPQMVEQIRAKNQLGKLGWFVGQMMRMGEKGRVEAQKADEILRELILGKSDQP
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial, Glu-AdT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GARL_CITK8
Sequence: MMSNDIFPNKFKAALAAQRIQIGCWSALANPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETEEEAVRAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPEVQKTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADAFKK
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde.
What are the official names of this protein?
5-keto-4-deoxy-D-glucarate aldolase, KDGluc aldolase, KDGlucA, 2-dehydro-3-deoxy-D-glucarate aldolase, 2-keto-3-deoxy-D-glucarate aldolase, 5-dehydro-4-deoxy-D-glucarate aldolase, Alpha-keto-beta-deoxy-D-glucarate aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family. KDGluc aldolase subfamily.
Protein: MTND_RHOPA
Sequence: MATLLFDDGREATAAEIEAIARAHRIVVEHRPVPAALAETLARPLLDDTSAATVLDALPPRPEFPSRDLIVLHPDRPDNEQLATKFENWHRHAGDEIRHILDGAGIFGVIVDGQRADLHVGPGDFIVVPAGLEHNFRLTAARRIKAVRYLSDAEGWSAEFTGRAA
What is the function of this protein?
Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site.  Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway.  Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
What are the official names of this protein?
Acireductone dioxygenase, 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, DHK-MTPene dioxygenase, Acireductone dioxygenase (Fe(2+)-requiring), ARD', Fe-ARD, Acireductone dioxygenase (Ni(2+)-requiring), ARD, Ni-ARD.
What is the protein family that this protein belongs to?
Belongs to the acireductone dioxygenase (ARD) family.
Protein: KV37_HUMAN
Sequence: MEAPAQLLFLLLLWLPDTTREIVMTQSPPTLSLSPGERVTLSCRASQSVSSSYLTWYQQKPGQAPRLLIYGASTRATSIPARFSGSGSGTDFTLTISSLQPEDFAVYYCQQDYNLP
What is the function of this protein?
Probable non-functional open reading frame (ORF) of V region of the variable domain of immunoglobulin light chains (PubMed:24600447).  Non-functional ORF generally cannot participate in the synthesis of a productive immunoglobulin chain due to altered V-(D)-J or switch recombination and/or splicing site (at mRNA level) and/or conserved amino acid change (protein level) (PubMed:9619395).  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:20176268, PubMed:17576170).
What are the official names of this protein?
Probable non-functional immunoglobulin kappa variable 3-7.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: PETG_GOSBA
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RN185_DANRE
Sequence: MASAAASESSSSSSSSSAGAANGQSAGESGGGGAQDSTFECNICLDTSKDAVISLCGHLFCWPCLHQWLETRPNRQVCPVCKAGISRDKVIPLYGRGSTGQQDPREKTPPRPQGQRPEPENRGGFQGFGFGDGGFQMSFGIGAFPFGIFATAFNINDGRPPPAAPGTPQHTDEQFLSRLFLFVALLIMFWLLIA
What is the function of this protein?
E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination.  Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation.  Protects cells from ER stress-induced apoptosis.  Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway.  Also acts as a regulator of the innate antiviral response by catalyzing 'Lys-27'-linked polyubiquitination of CGAS, thereby promoting CGAS cyclic GMP-AMP synthase activity.  Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2 (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF185, RING finger protein 185, RING-type E3 ubiquitin transferase RNF185.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RNH_CLOBL
Sequence: MKKVIIYTDGACRGNGQENTIGAYGIVLMYGEHKKEIKKAFRDTTNNIMELSAVVEALSLLKEPCSIELYSDSAYVINAINQKWLDNWKKNNWKTASKSPVKNKELWEKLDELLKKHSVKFIKVKGHSDNEYNNRCDKLANEAMDEFNV
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.