PharMolix/UniProtQA huggingface dataset:
Protein: GATB_STRPQ
Sequence: MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNSFSNVRKGLEFEVERQAKLLRSGGAIRQETRRYDEANKGTILMRVKEGAADYRYFPEPDLPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVSLGGDAKQVSNWLQGEVAQFLNAEGKTIEEIALTPENLVEMIAIIADGTISSKMAKKVFVHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVAQQLLAQELQKLRD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RS6_HELPG
Sequence: MRHYETMFILKPTLVEEEIKSKIEFYKEVITKHHGVIETSLDMGMRNLAYEIKKHKRGYYYVAYFKAEPSMILELERLYRINEDVLRFIVIKYESKKEVEAWHALVDRANKKPSHAKEKHEKTEHAHSHHAEEAKSTESHSE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MUG_CITK8
Sequence: MVKDILARELRVVFCGINPGLSSAGTGFPFAHPANRFWKVIHLAGFTGRQLKPEEAQHLLDFRCGVTKFVDRPTVQANEVKLQEMRSGGHKLIEKIEHYQPAALAILGKQAFEQGFSQRGAQWGKQTMTIGDTQIWVLPNPSGLNRIRTEKLVEAYRELDESLVVDGL
What is the function of this protein?
Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA.  It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base.  The complementary strand guanine functions in substrate recognition.  Required for DNA damage lesion repair in stationary-phase cells.
What are the official names of this protein?
G/U mismatch-specific DNA glycosylase, Double-strand-specific uracil glycosylase, Mismatch-specific uracil DNA-glycosylase, MUG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. TDG/mug family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSHRC_BRARP
Sequence: MARKMLSDGELNKAAAAGEEATTETHYDFDLFVIGAGSGGVRAARFSANNGAKVGICELPFHPISSEEIGGVGGTCVIRGCVPKKILVYGATYGGELEDARNYGWEINGNVDFNWKKLLQKKTDEILRLNNIYKRLLANAAVKLYEGEGRIVGPNEVEVRQIDGTKISYTAKHILIATGSRAQKPNIPGHELAITSDEALSLEEFPKRAIVLGGGYIAVEFASIWRGMGATVDLFFRKELPLRGFDDEMRALVARNLEGRGINLHPQTSLAELIKTDDGIKVISSHGEEFVADVVLFATGRIPNTKRLNLEAVGVELDQAGAVKVDEYSRTNIPSIWAVGDATNRINLTPVALMEATCFANTVFGGKPAKADYTNVACAVFCIPPLAVVGLSEEEAVEKATGDILVFTSGFNPMKNTISGRQEKSLMKLIVDEKTDKVIGASMCGPDAAEIMQGIAIALKCGATKAQFDSTVGIHPSSAEEFVTMRTVTRRIAYKAKPQTSL
What is the function of this protein?
Maintains high levels of reduced glutathione in the cytosol.
What are the official names of this protein?
Glutathione reductase, cytosolic, GR, GRase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM1_ARCFU
Sequence: MEVEEGRARVKVEGVFYNPRMRFCRDLDMLVFATMDSKEYFDALSASGIRGIRAALEAGKKAVFNDVSPKAVKVIEENLRENGVSGEVINGDAAAVMRQRAFEHIDIDPFGSPAPFMDSACFSAKRYLSVTATDTAALCGSATNSGLKKYGAFAVKTDVYHEVGLRMLIGFVVREATKYEKALFPLISWVREHYYRVHFKIKKSTAMSAKVYEKMGYLAYCSTCLRKKVLGMGEGAERCECGGKFSLIGPIWLGELKQRDFAEKVAEKAEGKLRAFLEKILAEIDAPTAYSLPALAKIHSLTLPPTDVVVEELKKLGYEASRTHYCGFCVKTDADRDVVVKILRSRKII
What is the function of this protein?
Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups.
What are the official names of this protein?
tRNA (guanine(26)-N(2))-dimethyltransferase, tRNA 2,2-dimethylguanosine-26 methyltransferase, tRNA(guanine-26,N(2)-N(2)) methyltransferase, tRNA(m(2,2)G26)dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
Protein: FER8_USTMA
Sequence: MTIDLSLKSNQQKTIAVLGASYAGHRAIQVLVASLPEDWRVVVLERNTHANHLYAFPRMSVVRGHEQKVFIPYTNMFKPALDRRDQHVLLHANVLELDQEQRRVSYELIDDKQSGVQWLHWDFLVYALGSHLPDPINVWSNSEHVNTHDGSKMMGVKWLRDAQDRIEKAESIVIVGGGALGVQLATDIAVTYGSSKKVTLTHSRPQLLPRFDPWMHEKTAARLQELGVELALGSRVDLSTVSEDKKRFKLLDGRELQGDLTLFCLGQTPNTSLLGASSLNDSGMAKVEPTLQLSANERIFVIGDAADAFGAINAGHTAWDQAEVAAKNILALIDNKGQAMKLEEYKPTPPAIKVSLGIDRAIRQTMAGELVEVDSGSIDLNSTNMWTRRGLSTDDLWQ
What is the function of this protein?
Protein of unknown function; part of the gene cluster that mediates the biosynthesis of siderophore ferrichrome A which is contributing to organismal virulence (PubMed:17138696, Ref. 4).
What are the official names of this protein?
Fe-regulated protein 8.
Protein: GPH_VIBPA
Sequence: MTQQDIKLIAFDLDGTLLDSVPDLAVAADQAVQALGYPAVSEEQVRDYVGNGADVLIGRALSQSMTISSDLSEDLRAKGRELFDDFYAQSGHQLSHLYPTVKETLEELHQAGFTMALVTNKPSKFVPEILEQHGIAKYFVDVLGGDAFPEKKPNPVALNWLMEKHQVKASEMLMVGDSKNDILAAKNAGCASFGLTYGYNHGEPISASNPDFVADSLSELLEVVAVSA
What is the function of this protein?
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate.  Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
What are the official names of this protein?
Phosphoglycolate phosphatase, PGP, PGPase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Protein: SPT4_CRYNB
Sequence: MPPKSGRAELRACLVCSILQSTNDFLTQGCPNCEDILEMRGSAERVAECTSLLYDGMIAMIEPSESWVARWQRIDKRMRGIYAVRVTGRAPQDVIDAIEARGGVYRPRDAVED
What is the function of this protein?
The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4, Chromatin elongation factor SPT4.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Centromere and heterochromatin.
Protein: RECA_THENN
Sequence: MAEEKQKKSVLEKALKRIEENFGKGSIMILGDETQVQPVEVIPTGSIAIDIATGVGGYPRGRIVEIFGPESSGKTTLALHAIAEAQKMGGVAAFIDAEHALDPVYAKNLGVDLKSLLISQPDHGEQALEIVDELVRSGVVDLIVVDSVAALVPRAEIEGAMGDMQVGLQARLMSQALRKIAGSVNKSKAVVIFTNQIRMKIGVMFGSPETTTGGLALKFYATMRLEVRRGEALKEGKDVIGNVVNVKIVKNKVAPPFKTAQTYIIYGKGIDREYELFHIGVDEGVITRKGSWYYYTTLKGEEVSLGQGGSNVVQFLKENPQIAEEIERRIKEKYGLLRQTEKEPEKADKSS
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3793_MYCBO
Sequence: MPRTDNDSWAITESVGATALGVAAARAAETESDNPLINDPFARIFVDAAGDGIWSMYTNRTLLAGATDLDPDLRAPIQQMIDFMAARTAFFDEYFLATADAGVRQVVILASGLDSRAWRLPWPDGTVVYELDQPKVLEFKSATLRQHGAQPASQLVNVPIDLRQDWPKALQKAGFDPSKPCAWLAEGLVRYLPARAQDLLFERIDALSRPGSWLASNVPGAGFLDPERMRRQRADMRRMRAAAAKLVETEISDVDDLWYAEQRTAVAEWLRERGWDVSTATLPELLARYGRSIPHSGEDSIPPNLFVSAQRATS
What is the function of this protein?
Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
What are the official names of this protein?
Putative S-adenosyl-L-methionine-dependent methyltransferase Mb3793c.
What is the protein family that this protein belongs to?
Belongs to the UPF0677 family.
Protein: HCHA_ECO7I
Sequence: MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHSDNPLNGYSICAFPDAADKQTPDIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAS
What is the function of this protein?
Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals.  Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively.  Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals.  Acts on early glycation intermediates (hemithioacetals and aminocarbinols), preventing the formation of Schiff bases and advanced glycation endproducts (AGE).  Also functions as a nucleotide deglycase able to repair glycated guanine in the free nucleotide pool (GTP, GDP, GMP, dGTP) and in DNA and RNA.  Is thus involved in a major nucleotide repair system named guanine glycation repair (GG repair), dedicated to reversing methylglyoxal and glyoxal damage via nucleotide sanitization and direct nucleic acid repair.  Plays an important role in protecting cells from carbonyl stress.
What are the official names of this protein?
Protein/nucleic acid deglycase HchA, Maillard deglycase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C56 family. HchA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EDC1_DEBHA
Sequence: MMAHELPLSIHTKKSNHNVPPSKAPSAKTNKHKPSKSGSDDRGLPNGGKVDFGNKSGSQTNKKSNKKTSKHTSSNTSNNKGVTRVLPDGSKPNFGNESSHQNGGNHKKQNNEPCLPNGEKPNFGEGSKSHSKKKNNDHVLPNGEKPNFFNEKSSKKATKPKEKKPLITEDTYAGSSFHSSPAALNLPKPSFKTSPKTNDAKQHTTEPNYHVNPQVNTPPQHSVNVPPQHPVTTYPAGNGVPNIPTVPSNPTAFPPRNHYAQPGFSYYATPQGYINYQYPQVPPPPPPQGGVYPMVAPQYQQQPQQHPQQHPQPQPQPQQLPQQHRPHHLPAIAAPQQGHRISFNELLGSSKS
What is the function of this protein?
mRNA-binding protein which stimulates mRNA decapping.
What are the official names of this protein?
Enhancer of mRNA-decapping protein 1.
What is the protein family that this protein belongs to?
Belongs to the EDC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG25_MILVL
Sequence: MSQFKDKSILKSNEVPEEMFTCISGSTDTNSEMKTVISKEKNEEKSLVKTKNKVNRIRLFLNYHVKELPIMDHSIAERNSEMMKTVMRYKTSYREVTRFLIGSWLLFAEKLIPPFNMKAIIIIETDQELVDVADFEGIEILLGNNIQSCLDSFYMRFYKEDLILYNTANELLLLIDNFKIPKYFAKLDMNQVRLKKIIEKKYMSLIKAGKL
What are the official names of this protein?
Uncharacterized 25 kDa protein.
Protein: TRMB_ACIF2
Sequence: MEEALKTSHRAIRSFVLRQGRITAAQTRAVAEYLPARQIDAHAEWRDPWNNQRPLMLEIGFGNGEHLAAIAAQRPTWGCIGIEVHTPGVGSLLLQLVEAGTDNVRIVHDDAVTWLKTLPDAILRCIIIQFPDPWPKKRQQKRRLIQPDFAAVLCRLLQPGGELQLATDWADYAGQMLTVLNATPGLQNADADNGYVFRPDNRILTRFERRGQRLGHAVYDLCYRRIP
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: PUR9_STRE4
Sequence: MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGVVTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNLYPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELASTGSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENPQQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHMNPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGYSKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIVVTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQATGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: S22AJ_MOUSE
Sequence: MAFQDLIIQIGSLGRFQILHMIFVLICHALSAPHTLLENFTAAIPSHRCWVPILDNDTASDNGSRILSQDDLLRISIPLDSNLRPDKCRRYIQPQWHLLHLNGTFPTVTEPDTEPCVDGWVYDQSTFLSTTVTQWDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDKFGRKLIFTCSLLKMAITETCVAFAPSFLIYCSLRFLSGIFSSTLRTNSALLILEWTSPKFQALVMALIFIASGVGQTLLGGLAFAFRNWHHLQLALSVPMFLLLIPTRWLSESARWLIMANKPQKSLKELKKAACVNRIKNSGDALTLEVVKTIMKEELEAAQTKPSPLDLFRTPNLRKRICLLSFVRFVSVMSLLGLLINIQYLSNNVFLLQCLYGVVCIPANVLGNFSMNYMGRRMTQLIFMSVLGISILAVVFLPQEMQILRVFLSTLGGAISSASITSTLVHANELVPTIIRATALGVVGIAGSAGGALSPLLMILTTYSASLPWIIYGILPFLGGLVALLLPETKNQPLPDSIQDIENKRKSSKEAKKDVVAKVTPL
What is the function of this protein?
Sodium-independent organic anion transporter which shows high specificity for estrone sulfate, dehydroepiandrosterone sulfate, and the mycotoxin ochratoxin A (OTA) (PubMed:15068970, PubMed:16150593).  Transport of OTA is strongly inhibited by estrone sulfate and probenecid, and to a lesser extent by 2,4-dichlorophenoxyacetic acid (2,4-D) and salicylate (PubMed:15068970).  Transport of estrone sulfate is inhibited by various steroid sulfate conjugates including dehydroepiandrosterone sulfate, alpha-naphthyl sulfate, beta-estradiol sulfate, 4-methylumbelliferyl sulfate and p-nitrophenyl sulfate (but not minoxidil sulfate) (PubMed:16150593).
What are the official names of this protein?
Solute carrier family 22 member 19, Organic anion transporter 5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
What are the subcellular locations of this protein?
Apical cell membrane; Multi-pass membrane protein.
Protein: RM11_YEAST
Sequence: MLQLRFMPGWVPRNGFFGLKETIGTVHKRFYALASEQPSRKTVKPLDSRKTFLIDTYKHLMENSSMIFFVHYNNLSKTEDHHFRFKIKQTGGKLTKVRNNLFEVYLRNSHLPDPCGFVKRKEQNWKHPLLPLLKGPTATITYEDTNPQQVAKLLKVLQSAQDKLMVIGAKVENEVLNVEKINTFKTLPTKPEMQSQLVSVLQMLSGLGLVRTLENSSNALYLTLKSHNDNQKPKEDVESTTDAESKGSK
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
54S ribosomal protein L11, mitochondrial, Mitochondrial large ribosomal subunit protein uL10m, YmL11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: 6PGD3_ARATH
Sequence: MESVALSRIGLAGLAVMGQNLALNIADKGFPISVYNRTTSKVDETLDRASNEGKLPVAGQYSPRDFVLSIQRPRSVIILVKAGAPVDQTISALSEYMEPGDCIIDGGNEWYQNTERRIVEAEKKGLLYLGMGVSGGEEGARNGPSLMPGGSFTAYNNVKDILEKVAAQVEDGPCVTYIGEGGSGNFVKMVHNGIEYGDMQLISEAYDVLKNVGGLSNDELAEIFTEWNRGELESFLVEITSDIFRVKDDYGDGELVDKILDKTGMKGTGKWTVQQAAELSVAAPTIAASLDCRYLSGLKDERENAAKVLEEAGLKEDIGSASRGVDKKRLIDDVRQALYASKICSYAQGMNLLRAKSLEKGWDLNLGEMARIWKGGCIIRAVFLDRIKKAYQRNPNLASLVVDPDFAKEMVQRQAAWRRVVGLAISAGISTPGMCASLAYFDTYRRARLPANLVQAQRDLFGAHTYERTDRPGAYHTEWTKLARKSQ
What is the function of this protein?
Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
What are the official names of this protein?
6-phosphogluconate dehydrogenase, decarboxylating 3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the 6-phosphogluconate dehydrogenase family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Cytoplasm, cytosol.
Protein: Y3130_YERPA
Sequence: MKRTKNINQETFRKSWRSYRLAPVALAVSAVFMLAGCEKTDETVSLYQNADDCSQANPSQSAECTTAYNTALQEAVKTAPKYATREDCVAEFGESQCTQAPAQAGMVPTSSSETTAAAPQQSGSMWMPLMAGYMMGRMMGGGASQPLFTSKAPNSPANGKFVDASGKNFGAATTGRTMTVPKTALAPKPAVTKTITRGGFGESVAKQSSMQRSAATSSKTTTRSMGG
What are the official names of this protein?
UPF0441 protein YPA_3130.
What is the protein family that this protein belongs to?
Belongs to the UPF0441 family.
Protein: H32_PETCR
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVAALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3.2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: HEM3_SHESA
Sequence: MSENRIRIATRKSPLAMWQAEFVKAELERVHPGIVVELLPMSTKGDVILDTPLAKVGGKGLFVKELEVAMLEDQADIAVHSMKDVPVDFPEGLGLEVICEREDPRDAFVSNLYKSISELPLGATVGTSSLRRQCQLRASRPDLIIKDLRGNVGTRLAKLDNGEYDAIILAAAGLIRLKLSERIASFISAEESLPANGQGAVGIECRTNDERVKALLAPLEHLETRYRVIAERAMNTRLEGGCQVPIGAFAEIHGDEMTLRGLVGNPDGSEIIEGVITGPKTEATKLGVALAEELLSKGAKSILDAVYAKA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: ASPA_ACAM1
Sequence: MNTNHIRQVVIVGGTHGNERIGLYLVKKFNQDSSLLFRPNLTTNCLIGNPQACKENQRYIETDLNRCFIKADLDNHLLGRHEEKQAKVLHEQLGPKGNSENFLLDLHSTTANMGLTLILVNDHPFNLHLAAYLTHHNPQVRVYRWTQENQENAFVSSLCQLGFAIEVGPIPQGILLASLFKETETLIHQTLDYLEQVNRGASPPLPKTLTLFQHLEVVDYPKTSNGELAGMIHPQLQGRDYQPLNPGDPIFLTFEDQTLFYEGCSTVWPIFINEAAYYEKGIAMCLTHKQDISLK
What are the official names of this protein?
Probable aspartoacylase.
What is the protein family that this protein belongs to?
Belongs to the AspA/AstE family. Aspartoacylase subfamily.
Protein: HBB_AQUCH
Sequence: VHWTAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFASFGNLSSPTAIIGNPMVRAHGKKVLTSFGEAVKNLDNIKNTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFTKDFSPDCQAAWQKLVRAVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LPXH_ECOUT
Sequence: MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHHQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CDC37_CAEEL
Sequence: MPIDYSKWKDIEVSDDEDDTHPNIDTPSLFRWRHQARLERMAEKKMEQEKIDKEKGTTSKKMEELEKKLAAADVTDKSDIQKQIDEVKAQEEAWRKKEAELEEKERLEPWNVDTIGHEAFSTSRINKITEKKPQAPKTDEEDTHAMSTFFETHESLLEKMAVLKNGAKSTELFLAEHPHMASEYTANWLTIEALNAAIDFNEEKMKTMAEQCIIIQYLLELSKSLNAVATNTTVQKQFFKKFEAAEPVYMKHYQDEVKAFEDRLRTRAQTKRDAAMEEAEAEEKAERMKSAPGGIDPQEVFEQLPEEMRKCFEAHDIEALKGVAQKMDEEVFKYHFDRCIASGLWVPGKADDDDDDEEAAPAEEEPTTSS
What is the function of this protein?
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (By similarity).  Inhibits daf-21/Hsp90 ATPase activity (PubMed:23569206).
What are the official names of this protein?
Probable Hsp90 co-chaperone cdc37, Cell division cycle-related protein 37, Hsp90 chaperone protein kinase-targeting subunit.
What is the protein family that this protein belongs to?
Belongs to the CDC37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_STRA3
Sequence: MGKFQVISHPLIQHKLSILRRTTTSTKDFRELVDEIAMLMGYEVSRDLPLEDVEIQTPVATTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGMYRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGAASIKFVCLVAAPEGVAALQEAHPDVDIYTAALDEKLNEHGYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: RNH2_RHOPA
Sequence: MIRDTKQPIKVPAKPASRSGGKAKTVKPKTVKPKAVKAADGKAASAKASTSKAAVSKTSAKAAAAKPASAKGLKGVIAMAPPSFRRERALIKRGIWPIAGCDEAGRGPLAGPVVAAAVVLDPKRVPKGLDDSKRLSAEKREALFEEICATAQVSVVYASPERINRDNILRASLWALTRAVHALPDLPRHVFVDGRDRLATQCDCEAVIGGDGLIASIAAASIIAKVSRDRLMCKLAEQCPGYGFEQHKGYGVPEHLDALARLGPTVHHRRFFAPVAAAWQKIEGAPQPQIRDLFEADVTVEATA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IML2_YEAS7
Sequence: MFRVFGSFGSKGNQSSGEEQSTKTKQVLKQANDFEIALKAMDFVLDDRTDEGLNLLKKAEMETGSDQTILTLARGVIEFLQATLSFETEEMKRAAITLGKAEQMSWKSKQNAEKTNFRSSSIYPPGTVYAVTYTESCLLHALLMLFSESMMEAAKALLKLRRAYTMLQDIMVTVKKAERSKNSSSPSPSEKSQESCGSFVSAETTFISVDIPYKLSSEDKSNPLLLEFAEKIYTMRMGRLSGAHIGNTPSFHRLRDDLGLQTTPSQASDRHSVSDDFDLEQATIDEFIHSGANLCYGILQVVLSLLPPAIGAVLSIVGFKGSREEGLRLVWKAIKERNVHGCIGLLGLMFYYDGPFQFTDADFDIPPNDNGSRALNKSRTNDSSLLPGYMDSATLLHPGKILEDALLKARALFPNSALWLLNEAKMLAGKGRLRDSLALMDSIDVNSIRMRQVKSLMVFERAILLVNLHEYNRAADDLISLLDISDWSHALYTYFAGCCYLENWRMTQLGLLNDGKEQFYKERARELIFDAPSLLGKKTFKSKNLPLDRFMLRKVQQFNNMQKKLNLQEPLDSIATSPVHELAYFYNGYNRMTENDLILTKKMLTEYHNPAIDSEDPDQELIRNLLLSLTLRRLGDAERGLALLDDIVLPKIFYIQNGKVKYFKKTEDPWAYPAALYERALFCWKLGGMESLNECREWLLRAQNYAADYELSTRIGMKIKAALDRVENALA
What is the function of this protein?
Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins.  Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing.
What are the official names of this protein?
Inclusion body clearance protein IML2, Increased minichromosome loss protein 2.
What is the protein family that this protein belongs to?
Belongs to the IML2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localized exclusively in cytoplasmic inclusion bodies under protein folding stress conditions.