PharMolix/UniProtQA huggingface dataset:
Protein: ECM33_YEAS6
Sequence: MQFKNALTATAILSASALAANSSTSIPSSCSIGTSATATAQADLDKISGCSTIVGNLTITGDLGSAALASIQEIDGSLTIFNSSSLSSFSADSIKKITGDLNMQELIILTSASFGSLQEVDSINMVTLPAISTFSTDLQNANNIIVSDTTLESVEGFSTLKKVNVFNINNNRYLNSFQSSLESVSDSLQFSSNGDNTTLAFDNLVWANNITLRDVNSISFGSLQTVNASLGFINNTLPSLNLTQLSKVGQSLSIVSNDELSKAAFSNLTTVGGGFIIANNTQLKVIDGFNKVQTVGGAIEFTGNFSTLDLSSLKSVRGGAKFDSSSSNFSCNALKKLQSNGAIQGDSFVCKNGATSTSVKLSSTSTESSKSSATSSASSSGDASNAQANVSASASSSSSSSKKSKGAAPELVPATSFMGVVAAVAVALL
What is the function of this protein?
Required for proper cell wall integrity and for the correct assembly of the mannoprotein outer layer of the cell wall.  Important for apical bud growth (By similarity).
What are the official names of this protein?
Cell wall protein ECM33, Extracellular mutant protein 33.
What is the protein family that this protein belongs to?
Belongs to the SPS2 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Secreted, cell wall. Note=Identified as GPI-anchored plasma membrane protein (GPI-PMP) as well as covalently-linked GPI-modified cell wall protein (GPI-CWP) in the outer cell wall layer.
Protein: THIB_SALTY
Sequence: MLKKYLPLLLLCAAPAFAKPVLTVYTYDSFAADWGPGPAVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLEAATQTKLFAKSGVANEAVKVPGGWKNDTFVPFDYGYFAFVYDKSKLKNPPKSLKELVESDQKWRVIYQDPRTSTPGLGLLLWMRKVYGDNAPQAWQKLAAKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHIIEEKKDNYAAANFSEGHYLQVEVAARTVASKQPELAEKFLKFMVSPAFQNAIPTGNWMYPVADVALPAGFESLAKPATTLEFTPQQVAAQRQAWISEWQRAVSR
What is the function of this protein?
Part of the ABC transporter complex ThiBPQ involved in thiamine import (PubMed:9535878).  Is also involved in thiamine pyrophosphate transport (PubMed:9535878).
What are the official names of this protein?
Thiamine-binding periplasmic protein.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PSD_RHOBA
Sequence: MKYYRNQDSYWWADADDPFLWRESLPFVRVGLAELIIMTLVSLVLAVIAGWFWWPLAVPFVLVAALVAWFFRNPRRKVPETIGTVVSPADGKLVEIVEVDDPIIGAAVRFGIFLSVFNVHANRIAMPGRVVRVRYRPGKFLNALRSESTKENENIDVELECPEIGGRIVRIRQITGQFARRIVCWARVGDVLQRGEMFGMIKLGSRTELVIPRDEALEIVAQVGEKVCAGSTVFARYQQG
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: RECF_BACP2
Sequence: MYIQSLALTSYRNYEHTELQFDNKVNVMIGENAQGKTNLMEAIYVLSMAKSHRTSNDKELIRWDQDYAKIEGRVIKKNGPLPMQLVISKKGKKGKVNHIEQQKLSHYVGALNTIMFAPEDLSLVKGSPQIRRRFLDMEIGQVSAVYLHDLSLYQKILSQRNHYLKQLQTRKQTDQAMLEVLTEQLIDAAAKVVKRRLTFTKQLEKWAQPLHFGISRELETLTLQYHTAIEVSEASDLSKIKNSYEESFQKLRDREIDRGVTLWGPHRDDLLFFVNGRDVQTYGSQGQQRTTALSLKLAEIDLIHEEIGEYPILLLDDVLSELDDYRQSHLLHTIQGRVQTFVTTTSVEGIDHATLKEAEIFRVASGKVID
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MME1_DROME
Sequence: MEEVEISTEKKSNPVKSFIAGGVGGMCNVLVGHPLDTIKVRLQTMPTPPPGQPPRYKGVIDCAARTFRYEGFRGFYRGISAPLVGVTPIYAVDFAVYAAGKRLFQTDDHIRLTYPQIFAAGALAGVCSALVTVPTDRIKVLLQTQTVSNGPLLYNGTIDTAAKLYRQGGIRSLFKGTCACILRDSPTGFYFVTYEFLQELARKKSANGKISTTSTILSGGTAGIVFWTLAVPFDVLKSRLQSAPEGTYKHGIRSVFRNLMATEGPKALFRGILPILLRAFPSTAAVFFGVELTNDLLKA
What is the function of this protein?
Mediates efflux of magnesium ions from mitochondria, suggesting a role in magnesium homeostasis.
What are the official names of this protein?
Mitochondrial magnesium exporter 1.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial carrier (TC 2.A.29) family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: ATP8_PHYMC
Sequence: MPQLDTSTWFLTILSVMLTLFTLLQPKISMHLYTPNPKPMPTKTQKQHSPWNTAWTKIYLPLL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: ADDA_STRPZ
Sequence: MLFNINEKGEPLVISFAPFLSPEAIKHLQENERCSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTFTVKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVLKQEVFSKLFSEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHDIELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDVTVSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAHFAIKILEENTDIRQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKTEQGKVILLKENFRSQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAKEIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRSPMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAYPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLILENFHERFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVATPKQAVNLMTIHKSKGLQFPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEEMRLLYVAMTRAEKKVYFIGKASKSKSQEITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRLQTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEPLLEPIGVDIIEKSSRSLSDFTLPHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYREAPFAILKLDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLMGGGKPEIVEV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddA nuclease domain is required for chi fragment generation; this subunit has the helicase and 3' -> 5' nuclease activities.
What are the official names of this protein?
ATP-dependent helicase/nuclease subunit A, ATP-dependent helicase/nuclease AddA, DNA 3'-5' helicase AddA.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddA subfamily.
Protein: RRF_BACC2
Sequence: MGQQVLKSSNEKMEKAVAAYSRELATVRAGRASSSVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_PROMS
Sequence: MTKERTFIAIKPDGVQRGYVSEILGRFEKKGFKLVGLKQLIPSKELAQNHYGVHRERPFFGDLVDFISSGPVVAMVWEGEGVILSARKLIGATKPLEAEPGTIRGDLAIDIGRNIIHGSDGEDTAKFEINLWFNEEELCEWETSDSKWRSEN
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPG_SYNC1
Sequence: MPELPEVETIRRGISPWVIDQKVVAVVVRQPRLRWPVPSNLSACLVGYAFSGVERRAKYLLLPNPAGCLLIHLGMSGSLRIVPSDTPPAAHDHVDIALESGRTLRLNDPRRFGAVLWIEGRPEDHALLAHLGPEPFAVEFTGAMLYARSRGRKLAVKNFIMDQRIVVGVGNIYASEALYRAGIHPMRAAGRVSRRRYAALAEAVRQVLTAAIEAGGTTLRDFTDENGRPGYFSQRLLVYGREGQPCVHCGRPIRCETIGQRSSYFCTRCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: P20D1_UNCRE
Sequence: MKSLILTTLALLPLVSCKPWVQLSHQTPISADRNLIPGAAEKSQLDKIIADSELLSLHRSLTEIESISSREGDVGDFLVDYLQKHGFTVEKQHVSSDGNEADKMKPSSFNVYAYPRSSPAPEIILTSHIDTVPPFIPYSLSLPKSSSTGSIDRRAIHISGRGTVDDKGSVACQIIAILSHLKSHPDARLGLLFVVGEETGGQGMHHFSRSPLNTSPPTFHTVIFGEPTENKLVSGHKGMLQFTVSVHGKPAHSGYPWLGRSAVSEILPILSKIDQLGDIPESEGGLPSSEKYGKTTLNIGFMEGGVATNVVPARAFARVAVRLAGGTVEQAKERITAAVRSASREYRADVRLWFFSGGGYPPIDLDTDVEGFDILAVNYGTDVPNLMIHDHDQPEDKKVKRYLYGPGSIFSAHGENEGLSVGDMEDAVEGYGRLIRAAVERGQRK
What are the official names of this protein?
Probable carboxypeptidase UREG_07869, Peptidase M20 domain-containing protein UREG_07869.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family.
What are the subcellular locations of this protein?
Secreted.
Protein: MATK_TRIRP
Sequence: MKEYRVYLERARSRQQDFLYPLIFREYIYGLAYSHNFNRSIFMENGGYDNKYSLLNVKRLITRMYQQNHLIISANDSNKNPFLGYNKNFYSQIISEGFAIIVEIPFFLQLSSSLEEAEIIKSYKNVRSIHSIFPFLEDKFTYLNYVSDIRIPYPIHLEILIQILRYWVKDVPFFHLLRLFLSHFCNWNCFIPTKKSISTFSKRNPRLFLFLHNFYVCEYESIFLFLRNKSSHLRLKSFSVFFERIFFYAKRKHLVEVFSKDFSYTLPFFKDPNIHYVRYQGKCILASKNVPFLMNKWKYYFIHLWQCFFDVWSQPRTININQLSEHSFQLLGYFSNVRLNRSVVRSQMLQNTFLIEIVSKKLDIIVPIIPLIRSLAKAKFCNVLGHPISKPVWADSSDFDIIERFLRICRNLSHYYNGSSKKKSLYRIKYILRLSCIKTLACKHKSTVRAFLKRSGSEELLEEFFTEEEEILSLIFPRDSFSLRRFHRNRIWYLDILFSNDLVNDE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: NPL4_HUMAN
Sequence: MAESIIIRVQSPDGVKRITATKRETAATFLKKVAKEFGFQNNGFSVYINRNKTGEITASSNKSLNLLKIKHGDLLFLFPSSLAGPSSEMETSVPPGFKVFGAPNVVEDEIDQYLSKQDGKIYRSRDPQLCRHGPLGKCVHCVPLEPFDEDYLNHLEPPVKHMSFHAYIRKLTGGADKGKFVALENISCKIKSGCEGHLPWPNGICTKCQPSAITLNRQKYRHVDNIMFENHTVADRFLDFWRKTGNQHFGYLYGRYTEHKDIPLGIRAEVAAIYEPPQIGTQNSLELLEDPKAEVVDEIAAKLGLRKVGWIFTDLVSEDTRKGTVRYSRNKDTYFLSSEECITAGDFQNKHPNMCRLSPDGHFGSKFVTAVATGGPDNQVHFEGYQVSNQCMALVRDECLLPCKDAPELGYAKESSSEQYVPDVFYKDVDKFGNEITQLARPLPVEYLIIDITTTFPKDPVYTFSISQNPFPIENRDVLGETQDFHSLATYLSQNTSSVFLDTISDFHLLLFLVTNEVMPLQDSISLLLEAVRTRNEELAQTWKRSEQWATIEQLCSTVGGQLPGLHEYGAVGGSTHTATAAMWACQHCTFMNQPGTGHCEMCSLPRT
What is the function of this protein?
The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome.  The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity).  Acts as a negative regulator of type I interferon production via the complex formed with VCP and UFD1, which binds to RIGI and recruits RNF125 to promote ubiquitination and degradation of RIGI (PubMed:26471729).
What are the official names of this protein?
Nuclear protein localization protein 4 homolog, Protein NPL4.
What is the protein family that this protein belongs to?
Belongs to the NPL4 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Endoplasmic reticulum. Nucleus. Note=Associated with the endoplasmic reticulum and nuclear.
Protein: CH10_STRCO
Sequence: MTTTSSKVAIKPLEDRIVVQPLDAEQTTASGLVIPDTAKEKPQEGVVLAVGPGRFEDGNRLPLDVSVGDVVLYSKYGGTEVKYNGEEYLVLSARDVLAIVEK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFR3B_MOUSE
Sequence: MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQAPEKEKENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAIIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGSKIIKEHEECMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSVHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPTYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLSQNLDGVVIEFLFRQSKISEVLGGSGYNSDRLCLPYIPQLTDEDRLSKRKSIGETISLQVEVESRNSPEKEERVPAEEITYETLKKAIVDSVAVEEQERERQRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISAAYGQPQNHSIPVYEMKFPDLCVY
What is the function of this protein?
Component of a complex required to localize phosphatidylinositol 4-kinase (PI4K) to the plasma membrane.  The complex acts as a regulator of phosphatidylinositol 4-phosphate (PtdIns(4)P) synthesis.  In the complex, EFR3B probably acts as the membrane-anchoring component.  Also involved in responsiveness to G-protein-coupled receptors; it is however unclear whether this role is direct or indirect.
What are the official names of this protein?
Protein EFR3 homolog B.
What is the protein family that this protein belongs to?
Belongs to the EFR3 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Cytoplasm, cytosol. Note=Palmitoylation anchors the protein to the plasma membrane. A small amount is observed in the cytosol.
Protein: YHAM_SALA4
Sequence: MFESKINPLWQSFILAVQEEVKPALGCTEPISLALAAAAAAAELDGTVERIDAWVSPNLMKNGMGVTVPGTGMVGLPIAAALGALGGDAKAGLEVLKDASAKAVADAKAMLAAGHVAVMLQEPCNDILFSRAKVYSGDSWACVTIVGDHTNIVRIETDKGVVFTQADNAQEEEKTSPLGVLSHTSLEEILAFVNAVPFDAIRFILDAARLNGALSQEGLRGSWGLHIGSTLAKQCDRGLLAKDLSTAILIRTSAASDARMGGATLPAMSNSGSGNQGITATVPVMVVAEHVGADDERLARALMLSHLSAIYIHHQLPRLSALCAATTAAMGAAAGMAWLIDGRYDTIAMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGIVAHNVEQSIANLCSLACRSMQQTDKQIIEIMASKAH
What are the official names of this protein?
UPF0597 protein YhaM.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: KDPC_ECOLC
Sequence: MSGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIREGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKLIAARVAALRAANPDASASVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIAKYSQQPLVKYIGQPVVNIVELNLALDKLDE
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: MDH_CHLT2
Sequence: MVSQTVSVAVTGGTGQIAYSFLFSLAHGDVFGLDCGIDLRIYDIPGTERALSGVRMELDDGAFPLLQRVQVTTSLHDAFDGIDAAFLIGSVPRGPGMERRDLLKKNGEIVATQGKALNTTAKRDAKIFVVGNPVNTNCWIAMNHAPRLLRKNFHAMLRLDQNRMHSMLSHRAEVPLSAVSQVVVWGNHSAKQVPDFTQALINDRPIAETIADRDWLENIMVPSVQSRGSAVIEARGKSSAASAARALAEAARSIYQPKEGEWFSSGVCSDHNPYGLPEDLIFGFPCRMLATGEYEVIPGLPWDAFIRGKMQISLDEILQEKASVSL
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 2 family.
Protein: RECX_ECO45
Sequence: MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDIWRNFAD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NTPPA_YERPA
Sequence: MTALYLASASPRRRELLALLDLPFEVLKTEVEEQRHPGESAQVYVQRLAQDKARAGVAVAPQDLPVLGADTIVVLNGQVLEKPRDKEHAQQILSALSGQKHQVMTAVALADRQNMLSAMVVTDVTFRVLSPLEISDYIATGEPMDKAGAYGIQGKGGCFVRAIAGSYHAVVGLPLVETHELLSHFIAQRNVRGIHDS
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_MYCMM
Sequence: MKVLAAMSGGVDSSVAAARMVDAGHDVVGVHLALSTAPGALRTGSRGCCSKEDASDARRVADVLGIPFYVWDFAERFKEDVIDDFVSSYARGETPNPCIRCNQRIKFSALYAKALALGFDVVVTGHYARLSEGRLRRAVDQDKDQSYVLAVLTAEQLRHAMFPIGDTPKPQIREEASRRGLAVADKPDSHDICFIPSGNTQTFLGERIGVRRGTVVDAAGAVLATHDGVHGFTIGQRKGLGIPGPGPDGRPRYVTAIDAETGTVRVGDVADLQVHALTGRAPIFTAGTAPTGPLECAVQVRAHGETTSAVAELVGDELSVRLHSPLRGVARGQTLVLYRPDPDGDEVLGSATITATSACSPVS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPF_STACT
Sequence: MFLKYCGFQTQDDIKYAVEQHIDAIGFIHYPKSKRHQSIDEIEILSNLVPDTIYRVAVVVNPTDDIINQLLSRTNINAIQFHGDEDREMLRWCKNKYPDVKIIKALPADDTLSKRIQQYKEEADLFIIDTPSIHYGGTGQSFDWQVLEEIQDVPYLVAGGMTKEKIQQFEALHLNAAGYDIASGIETNGSKDPMKMKEISEYIKGEKQI
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: C1D_MOUSE
Sequence: MAGEEMNEDYPVEIHESLTALESSLGAVDDMLKTMMAVSRNELLQKLDPLEQAKVDLVSAYTLNSMFWVYLATQGVNPKEHPVKQELERIRVYMNRVKEITDKKKAAKLDRGAASRFVKNALWEPKAKSTPKVANKGKSKH
What is the function of this protein?
Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5. 8S rRNA; this function may include MPHOSPH6.  Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA.  Can induce apoptosis in a p53/TP53 dependent manner.  May regulate the TRAX/TSN complex formation.  Potentiates transcriptional repression by NR1D1 and THRB (By similarity).
What are the official names of this protein?
Nuclear nucleic acid-binding protein C1D, mC1D, Small unique nuclear receptor corepressor, Sun-CoR, SunCoR.
What is the protein family that this protein belongs to?
Belongs to the C1D family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus, nucleolus. Note=EXOSC10 is required for nucleolar localization. Colocalizes with TSNAX in the nucleus.
Protein: CUTA_ECO24
Sequence: MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIPGATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTDYLSWLNASLR
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_ACTP2
Sequence: MRCPFCAAEETKVVDSRLAADGYQIRRRRECTSCKERFTTFESAELVVPYVIKNNGNRVPFDANKLRVSLSRALEKRPVSADDLEKAISKIIIQLQSTGEREVPSKLVGSLAMDALKQLDKVAYIRFASVYLSFDDIEEFTKEIEKLRE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PSD_SINFN
Sequence: MSLVETVRNTLVPVHKEGYRFIAIFFVVSLILGLLWEPLMWIGFLLTAWCAYFFRDPERMTPIDEDLVISPADGRVSSIATVTPPEELGLGSEPMLRISVFMNVFDCHVNRAPMSGTVRRIAYRAGSFLNAELDKASHDNERNGLVVETSHGAIGVVQIAGLVARRILCWTTENASLEGGERFGLIRFGSRVDVFLPEGAQPRVSVGQKAVAGETVIAEFGSSKGPLISRRA
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MIAA_PROMH
Sequence: MSEVKTQIKPKAIFLMGPTASGKTALAIALRQKLPVDLISVDSALIYRGMDIGTAKPDETEQSLAPHRLIDILDPALPYSAADFRKDALKAMEEITAAGRIPLLVGGTMLYFKALLEGLSPLPSANPEIRAEIEKKAAEQGWEAIHQELASVDPVAAKRIHPNDPQRLSRALEVYLISGKSMTELTQISGEALPYDVYQFAIAPKDRNVLHQRIEARFKQMLTCGFEDEVKSLYQRGDLHEDLPSIRCVGYRQMWSYLSGEIDYDEMVYRGICATRQLAKRQITWLRGWHDVHWLDSEDFEQSLNTVLQVVSA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.