PharMolix/UniProtQA huggingface dataset:
Protein: CHO2_EMENI
Sequence: MDRGLSTGTNQSGAGLRERAVTSQADLNVITENPTVTNASNGKDKAGKTFGRTPDGTVFTVPQTHDMVSQLLSPSEPKNLSDLVVLTILAGHIFLLWILPSGAKIPVFAVIYLFWRSCYNAGIGWLLHNQSHHKTLVRWAEKSQIFVNPATGKNPYPQLYHLIKRELEIKISKDYSFEEAPLEYNTWLVFRRLVDLILMCDFASYCLFAIACSRHPANESVLMTVIRWTSGIALVLFNLWVKLDAHRVVKDYAWYWGDFFYLIDQELTFDGVFEMAPHPMYSVGYAGYYGISLMAASYKVLFISIIAHAAQFAFLVLVENPHIDKTYNPPPPRKRTITEHDAASQRSQSPDTPNAPSVSEENVPNATTFSSPPPAVHNLLGFHNLDLHRITDTSSILVQFLMFSLTVLTPSTPWYQFLFVANAAIWRLWYSVGIGYLLNRQSNCKSWTRHFVKYGETPHEAWNQWKGTYHLSMVMCYASFISAVWKMYTLPSNWGYGLAILRHVLGAGLISLQIWTSVSIYESLGEFGWFYGDFFFDESPKLTYNGIYRFLNNPERVLGLAGVWGAVLITASGTVAFLAFLSHILSLGFIQFVERPHMQKLYGRSLRQDAGLVKSLKRSLPPSLRQLHGSVDKIFDESYEFIEEIIDTARPKLAAGVNTFVRDTTALFQKYPARVTISRIDADLAGYDLRDYSLTVEASQLPLDEGDLSKEGDNARTPLDRRGDLENLVFPYGTPVKVKWTAPLNHSKKDWIGLYKVTDNTSREVTRVSSQGRWVAVNEGFYDNLTCERGILISDVVVSTSQGDNGEKHDIATGEVVFSGDKLFWTQGVFEFRYHHNGKHNVMAISRPFEVRIPRFEEEDHFDMSQTAVETSLLPVIQNCFDRDPEIAPETPEEQYGSLVERDGKFAKRVVFAVHQMFGVEFAPEVVRSDGNVRNLAWRICNAKRVLAPYSMSRDGATTPTESKE
What is the function of this protein?
Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
What are the official names of this protein?
Phosphatidylethanolamine N-methyltransferase, PE methyltransferase, PEAMT, PEMT.
What is the protein family that this protein belongs to?
Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: F74A7_HUMAN
Sequence: MWRELRGCPGGDVETVQRLSRRRRGKSSEAVPEKTWRAQRMSQTRESSEAVPEKTWREFRGCPGEDVERAQRLRDCPGEDMETAQRLSARRRAESSEAVPEKTWRELKGCPQEDVERVQRLSLLLHLAVFLWIIIAINFSNSGVKSQSSTYLPSGKILK
What are the official names of this protein?
Protein FAM74A7.
What is the protein family that this protein belongs to?
Belongs to the FAM74 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: HIPK4_MOUSE
Sequence: MATIQSETDCYDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKNDAYRSRIIKNELKLLRCVRGLDPDEAHVIRFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLRALARLKELAIIHADLKPENIMLVDQTRCPFRVKVIDFGSASIFSEVRYVKEPYIQSRFYRAPEILLGLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQGLPKPHLLHAARKAHHFFKRNPHPDATNPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGGAVSRLSFPDREALAEHADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHEATRYYQLSLRGCRLSLQVDGKPPPPVIASAEDGPPYYRLAEEEETAGLGGVTGSGSFFREDKAPGMQRAIDQLDDLSLQEARRGLWSDTRADMVSDMLVPLKVASTSHRVPDSGPEPILAFYGSRLTGRHKARKAPAGSKSDSNFSNLIRLSQASPEDAGPCRGSGWEEGEGRTTSTEPSVIPQREGDGPGIKDRPMDAERPGPELFDPSSCPGEWLSEPEWTLEGIRGSRAQGLPAHHPHPHGPPRTTSFLQHVGGHH
What is the function of this protein?
Protein kinase that phosphorylates murine TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter.  May act as a corepressor of transcription factors (Potential).
What are the official names of this protein?
Homeodomain-interacting protein kinase 4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITPA_XENLA
Sequence: MAAAAGRSIVFVTGNAKKLEEVVQILGDKFPCKLVAKKIDLPEYQGEPDEISIQKCREAAKQIQGPVIVEDTCLCFNALGGLPGPYIKWFLEKIKPEGLHRMLEGFEDKSAIALCTFAYCNGNPDDTVLLFRGKTLGQIVLPRGPRDFGWDPCFQPDGFQQTYAELPKEVKNTISHRYRALKEMSDYFIQNGTKV
What is the function of this protein?
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives.  The enzyme does not distinguish between the deoxy- and ribose forms.  Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine triphosphate pyrophosphatase, ITPase, Inosine triphosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_NOCSJ
Sequence: MTTDSSPAPVRELLSVAMVTLGCARNEVDSEELAGRLEADGFRLVQDPAEADTVVVNTCGFVEAAKKDSVDTLLQAADLKARSEQGQGRTRAVVAVGCLAERYGKDLAASLPEADAVFGFDDYPDIAARLRSIVAGEAHEAHTPHDRRTLLPITPVERVLSTTPVPGHASGPASVRRRLDDGPTAALKLASGCDRRCSFCAIPAFRGSFLSRRPSDVLQEARWLADHGARELFLVSENSTSYGKDLGDLRLLETLLPELAAVDGVERVRVSYLQPAETRAGLIEAIASTPGVAPYFDLSFQHASAPVLRRMRRFGDPESFLALLAQVRGHAPAAGVRSNVIVGFPGETEQDLETLCDFLVAARLDVTGVFGYSDEDGTEAATYDGKLDDDEIRARVEHVSDLVEELTSQRAAERLGEQVEVLVERVEDGPGGRTVEGRAAHQGPEVDGATYLLDSDARVGDLVRAVVVGSEGADLDARPL
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PEAM2_ARATH
Sequence: MATPYKEERDIQKSYWMEHSSDLTVEAMMLDSKASDLDKEERPEVLSLIPPYEGKSVLELGAGIGRFTGELAQKAGEVIALDFIESAIQKNESVNGHYKNIKFMCADVTSPDLKIKDGSIDLIFSNWLLMYLSDKEVELMAERMIGWVKPGGYIFFRESCFHQSGDSKRKSNPTHYREPRFYTKVFQECQTRDASGNSFELSMVGCKCIGAYVKNKKNQNQICWIWQKVSVENDKDFQRFLDNVQYKSSGILRYERVFGEGYVSTGGFETTKEFVAKMDLKPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGLKCSVEFEVADCTTKTYPDNSFDVIYSRDTILHIQDKPALFRTFFKWLKPGGKVLITDYCRSAETPSPEFAEYIKQRGYDLHDVQAYGQMLKDAGFDDVIAEDRTDQFVQVLRRELEKVEKEKEEFISDFSEEDYNDIVGGWSAKLERTASGEQKWGLFIADKK
What is the function of this protein?
Catalyzes N-methylation of phosphomonomethylethanolamine and phosphodimethylethanolamine, the two methylation steps required to convert phosphomonoethanolamine to phosphocholine.  Unlike NMT1, NMT2 cannot utilize phosphoethanolamine as substrate in vitro.
What are the official names of this protein?
Phosphomethylethanolamine N-methyltransferase, AtPMEAMT, Phosphoethanolamine N-methyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. PEAMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELA_ECOLC
Sequence: MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLMLAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RTC5_LODEL
Sequence: MSCFKQDVYNCITPKTLSFVKSFLKQRSNDPAASTHLSSARVVEWNLNGIEVDSRARDELKAAVNILFRIMKYIGQFPFPKLSSKDDSEIISLTVQEFVIASVFISGRYRKLFGNDNGEIIWKFLFIALSHQSDMNFFEDDLDHLFTIPLKYPIEDGDSIAIKAQKVDWGGLEIIKKLSNLDMNQLQLQPSLFLNLTTLFLLTESIPNQKHNKMHDQFVHNLTTWKDFRKYSLDLLRYMNNDLSKDDLNSQTLSWSEFSLGMNNLLAPFVEVNLRKVVENNVLNISLPFFETSANSKMDGTGDEVPNGATTGTKTTMKENEGAGVEAQSKEETKVGNDVESSFGSKLVSISLIAYISSMLRGIGSTIEVTRFNAIKLFAGLEAGFSIRSLENKIYKWHAPTLLFVSGKRIKQRTIDTNRRYQEFDETYPKFFQANEDLLKSWQYTNDRITYCVLINQPWQNSNKKNFGDEKSLILSLEPRADYYTSLHSEILKGQLIYFNNSGMGLGFGNAQPLNKSNNKKYYPGDVSLTIESNLEFAVFRHLGSLSTNATTYFNRSRLPSTVAHEDFEDRFLITDLEVWGIGSKKELEEQQRQWKWEEQQAEARQSVNIRNMGEERAFLEMAGLVGNNGSGGSL
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 5.
What is the protein family that this protein belongs to?
Belongs to the RTC5 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_STAHJ
Sequence: MAKQPTALIILDGFANRESEHGNAVKQAHKPNFDRYYSKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIADGDFFENDVLNNAVQHVNEHDSALHVFGLLSDGGVHSHYQHLFALLELAKQKGLDKVYVHAFLDGRDVDQKSALKYIEETEAKFKSLGVGEFASISGRYYAMDRDKRWDREQKAYNAIRNFEGPAYASAKEGVEANYANDLTDEFVEPFIVEGQNNGINDGDAVIFFNFRPDRAAQLSEVFTNKAFDGFKVEQVKDLFYATFTKYNDNVDTEVVFEKVDLTNTIGEVAQNNNLKQLRIAETEKYPHVTYFMSGGRNEEFEGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELDKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMNGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVGQPSDMTGESLIKH
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: CH10_RAT
Sequence: MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGGKGKGGEIQPVSVKVGDKVLLPEYGGTKVVLDDKDYFLFRDGDILGKYVD
What is the function of this protein?
Co-chaperonin implicated in mitochondrial protein import and macromolecular assembly.  Together with Hsp60, facilitates the correct folding of imported proteins.  May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.  The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring.  In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per ring, followed by the binding of ATP and association with 2 heptameric rings of the co-chaperonin Hsp10.  This leads to sequestration of the substrate protein in the inner cavity of Hsp60 where, for a certain period of time, it can fold undisturbed by other cell components.  Synchronous hydrolysis of ATP in all Hsp60 subunits results in the dissociation of the chaperonin rings and the release of ADP and the folded substrate protein.
What are the official names of this protein?
10 kDa heat shock protein, mitochondrial, Hsp10, 10 kDa chaperonin, Chaperonin 10, CPN10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: LYSK_SULIK
Sequence: MQQEKELVKQKAKELLLDLLSIYTPSKNETNATKFFEKISNEFNLKLEILPDSNSFILGEGEILLASHVDTVPGYIEPKIENEVIYGRGAVDAKGPLISMIIAAWLLNEKGIKVMVSGLADEESTSIGAKELTLKNFNFKHIIVGEPSNGTDIVVEYRGSIQLDIMCKSTPEHSSSAKSNLIVDISKKIIEVYKQPENYDKPSIVPTIIRAGESYNVTPAKLYLHFDVRYAINNKRDDLINEIKDKFQECGLKIVDETPPVKVSINNPVVKSLTRALLKQNIKPRLVRKAGTSDMNILQKITTSIATYGPGNSMLEHTNQEKITLDEIYIGVKTYMLAIEELWQKS
What is the function of this protein?
Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
What are the official names of this protein?
[LysW]-lysine/[LysW]-ornithine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. LysK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLRX_ASPFU
Sequence: MKFSYSFVQVVTLLLSLSPSVEGFTRSRNDACKPNHPFRPLPPSQPRTKTCHVVSNGHGKDDSKNIMKALHKCNNGGKVVFDANKVYTVGTALDMTFLKHIDLEVLGKIQFTNDTDYWQANSFKHGFQNATTFFQLGGEDVNVYGGGTLDGNGQVWYDLYAEDALILRPILFGVIGLKGGTIGPLKLRYSPQWYQLVANSSDVIFDGIDISGYSSSKNEAKNTDGWDTYRSDNIVIQNSVINNGDDCVSFKPNSTNILVQNLHCNGSHGISVGSLGQYKGEVDIVQNVLVYNISMYNASDGARIKVWPGVSSAMSEDLQGGGGLGSVKNVTYNQMYIENVDWAIEVTQCYGQKNLTLCNEYPSNLTISDIHFKNFRGTTSGKRDPNVGTIVCSSPNVCSDIYAENIDVKSPKGTDNFVCTNVDKSLLDVNCA
What is the function of this protein?
Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates.
What are the official names of this protein?
Probable exopolygalacturonase X, ExoPG, Galacturan 1,4-alpha-galacturonidase, Poly(1,4-alpha-D-galacturonide)galacturonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: POL2_BAYMG
Sequence: MSTSSSRLFFDCGSLDWPNKSLFGDPTTRDVMDEHISSTWNAVIRRHMLAPNADAETILGRDGLPSAQFDAYGAMLPSFIQALNAPTTRLRISAPLSTAESILCADASHAPWLYMANSVCAYEATHLQPVQTFIAFNFAHGYCYLSLFIPLSFRITPENARSFSRFLEQLPDILGAYPTLASLYKTMLFAVRLFPEVLQAPIPIIAKRPGVLQFHVSDARGLPPSWFPMKCGSVASFIALITNNLNSDLLNGIVGSNGDGEHYTNWNSGHNHWIVNRFITVKDLHSSLKSALEVDLDTEGGRNAVLDLLLDLGVTNLVRREKRFPAYFQGAESVYLLLSCERVGNELVAVQDALQEPLANYTGKDLRALIINLGGLPSRHPEICYTRNIFENDNHLVWNFEFYRIASITKNAQIDRDVLSSSMANLFSDFVSESSNGEYRVKEPRPVTQYRVEHDEPVASGAPSAWWQVLVGITTAILGAIIFFLWRCFLRAKRVKFQAKDSFPWFTTSGDDDLPPPPGDSPSRPPGRSPDRVLPRTVVRDLSFNDDDDLHSVDLNEAGSRFGEVVSLIARGNLRELAGAIPESLSNLTLLQTSASGSGFYTMVALYLATLGDAITAFHEHNDASPATIQSLRTLELQLEARGLRFNEAGTPANLIQRGVKSSVGRALVRLTQSALLATGENFRTRMAATLERIAAERLNTLTAYDQRVIEMTTELLAAIKTALEVERSELTPHLANAEALLQVYNNLFSTDYASASLLALRREMILRSAEGRVGEQPTSASDAANEELVQRSMTKLDKEIELFQAQIDSQRRAVTITEASNLRENILQPINTVANIAMAGAFLRGGARHRMPGIPDVAAPMSNPFRAFSGRGHSLTTTRGAGLFRRPRV
What are the official names of this protein?
Genome polyprotein 2.
What is the protein family that this protein belongs to?
Belongs to the bymoviruses polyprotein 2 family.
Protein: RNPH_METRJ
Sequence: MRPSKRAADELRPVSLERAVSRYAEGSCLVSFGNTRVLCTASLEERAPPWLRGSGKGWVTAEYAMLPRATHERTRREVGSGKPSGRTQEIQRLIGRSLRAVTNLPAMGERQITIDCDVIQADGGTRTAAITGAWVALHDCFAWMRTRSIISVDPLRDHVAAVSCGLYKGTPVLDLDYAEDSAAETDANFVLTGRGGIVEVQGTAEMEPFTQEQLLELLGLARAGTERLVALQKEAIA
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: 3MGH_LISMH
Sequence: MDTIITNAFFENKTTIELARDILGMRLVHQTTNGKLSGLIVETEAYLGATDMAAHSFQNLRTKRTEVMFSSPGRIYMYQMHRQVLLNFITMPEGIPEAILIRAIEPEEQAKHLMEQNRGGKTGYELTNGPGKLTQALGLSMQDYGKTLFDSNIWLEEAKTPHLIEATNRIGVPNKGIATHFPLRFTVKGSPYLSAQRKSRILADIWE
What are the official names of this protein?
Putative 3-methyladenine DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
Protein: KPTA2_ARCFU
Sequence: MDLGICKRCGEFEGSCECGKGEVLLKSEDRKKVSKFLSGLLRHFGRDFGVRLDEDGWAELRDVLKILSERYGVGRKHVELIVKFDPKGRFELKNGRIRAKYGHSVEVRTDWSEGGEIPEKLYHATSPENLNSILKTGLLPMRRREVHMCSSPQEAIEVGKRHSSNPVLLEIDAKGLMQDGIEVRRKGKVYTVDFVPPKFIRVLSFDPRSPNPAKGY
What is the function of this protein?
Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P).  May function as an ADP-ribosylase (By similarity).
What are the official names of this protein?
Probable RNA 2'-phosphotransferase 2.
What is the protein family that this protein belongs to?
Belongs to the KptA/TPT1 family.
Protein: 3MG_MOUSE
Sequence: MPARGGSARPGRGALKPVSVTLLPDTEQPPFLGRARRPGNARAGSLVTGYHEVGQMPAPLSRKIGQKKQRLADSEQQQTPKERLLSTPGLRRSIYFSSPEDHSGRLGPEFFDQPAVTLARAFLGQVLVRRLADGTELRGRIVETEAYLGPEDEAAHSRGGRQTPRNRGMFMKPGTLYVYLIYGMYFCLNVSSQGAGACVLLRALEPLEGLETMRQLRNSLRKSTVGRSLKDRELCSGPSKLCQALAIDKSFDQRDLAQDDAVWLEHGPLESSSPAVVVAAARIGIGHAGEWTQKPLRFYVQGSPWVSVVDRVAEQMDQPQQTACSEGLLIVQK
What is the function of this protein?
Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
What are the official names of this protein?
DNA-3-methyladenine glycosylase, 3-alkyladenine DNA glycosylase, 3-methyladenine DNA glycosidase, ADPG, N-methylpurine-DNA glycosylase.
What is the protein family that this protein belongs to?
Belongs to the DNA glycosylase MPG family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion matrix, mitochondrion nucleoid. Nucleus.
Protein: DAAA_STAAN
Sequence: MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFTVTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHSFPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYAVKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYNIPFKEETFTVDFLKNADEVIVSSTSAEVTPVIKLDGEPINDGKVGPITRQLQEGFEKYIESHSI
What is the function of this protein?
Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine.  The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.  The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D-amino acid via a ping-pong mechanism.  This is an important process in the formation of D-alanine and D-glutamate, which are essential bacterial cell wall components (By similarity).
What are the official names of this protein?
D-alanine aminotransferase, D-amino acid aminotransferase, D-amino acid transaminase, DAAT, D-aspartate aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Protein: DSBB_PSYCK
Sequence: MLQLTTYRNLQVFLVIMTAIGMSFALFFLQRYMGFSPCPLCIFQRIGLMIMGGFALIAALFHPKSMVIRLLLWLGSLAGIGWAAIVAGRHVWLQHLPADQVPSCGPGLDYWLDTLPMQQVLKEVFAGSGECASIDWTFLGLSIPEQSLILFSILILTHLLILWRIVRPATPKPLAR
What is the function of this protein?
Required for disulfide bond formation in some periplasmic proteins.  Acts by oxidizing the DsbA protein.
What are the official names of this protein?
Disulfide bond formation protein B, Disulfide oxidoreductase.
What is the protein family that this protein belongs to?
Belongs to the DsbB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SERC_BACHK
Sequence: MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGNEKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTPPSFSIYVTKIVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPFTTPSEELNNEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYS_RICB8
Sequence: MLNIKWIRENQELFDDKLRQRFIEPMAKRIEELDGKKRKITNLIQEFQHARKVKSKILGNINPKSGEEFEGLQRDVKDINEKLEELEQDLNNNNELNELLNTLPNIPDEEVPYGIDESMNKLIRTHGEVDLNAQNKKQHFELGVKLDLMDFEQTAKISGARFVTLKGDLAKLERALANFMLDVHTGEFGFLEVSPPVLVRDNAMYNSGQLPKFADESFATTNGYRLIPTAEVSLVNMVADTIIPREKLPMRLVAYTPCFRSEAGSSGRDTRGMIRLHQFSKVELVSITTPEESKNEHEYMTNASETILQKLGLPYRTMLLCTGDMGFASQKTYDIEVWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSHDTTLVHTLNASGLPIGRTMVAILENYQNEDGSITVPDVLVNYMGGLQKITAYKE
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_NELNU
Sequence: MERGMRLFSSLVLVLLLVTATEMGPKVAEARTCESQSHRFKGACLSDTNCASVCQTEGFPAGDCKGARRRCFCVKPC
What are the official names of this protein?
Defensin-like protein, Gamma-thionin homolog.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: 3SX9_MICAT
Sequence: MRTLLLTLVVVTIVCLDLGNSLICYVTRDGKTATCPPGQKCEKYAVSASHTGHWFHRWHCTSTCHEGPYNVCCSTDFCNR
What is the function of this protein?
Neurotoxin.  Blocks muscular nicotinic acetylcholine receptors (nAChR).
What are the official names of this protein?
Three-finger toxin MALT0059C, 3FTx MALT0059C.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SDRD_STAAM
Sequence: MLNRENKTAITRKGMVSNRLNKFSIRKYTVGTASILVGTTLIFGLGNQEAKAAESTNKELNEATTSASDNQSSDKVDMQQLNQEDNTKNDNQKEMVSSQGNETTSNGNKSIEKESVQSTTGNKVEVSTAKSDEQASPKSTNEDLNTKQTISNQEGLQPDLLENKSVVNVQPTNEENKKVDAKTESTTLNVKSDAIKSNAETLVDNNSNSNNENNADIILPKSTAPKSLNTRMRMAAIQPNSTDSKNVNDLITSNTTLTVVDADNSKTIVPAQDYLSLKSQITVDDKVKSGDYFTIKYSDTVQVYGLNPEDIKNIGDIKDPNNGETIATAKHDTANNLITYTFTDYVDRFNSVKMGINYSIYMDADTIPVDKKDVPFSVTIGNQITTTTADITYPAYKEADNNSIGSAFTETVSHVGNVEDPGYYNQVVYVNPMDKDLKGAKLKVEAYHPKYPTNIGQINQNVTNIKIYRVPEGYTLNKGYDVNTNDLVDVTDEFKNKMTYGSNQSVNLDFGDITSAYVVMVNTKFQYTNSESPTLVQMATLSSTGNKSVSTGNALGFTNNQSGGAGQEVYKIGNYVWEDTNKNGVQELGEKGVGNVTVTVFDNNTNTKVGEAVTKEDGSYLIPNLPNGDYRVEFSNLPKGYEVTPSKQGNNEELDSNGLSSVITVNGKDNLSADLGIYKPKYNLGDYVWEDTNKNGIQDQDEKGISGVTVTLKDENGNVLKTVTTDADGKYKFTDLDNGNYKVEFTTPEGYTPTTVTSGSDIEKDSNGLTTTGVINGADNMTLDSGFYKTPKYNLGNYVWEDTNKDGKQDSTEKGISGVTVTLKNENGEVLQTTKTDKDGKYQFTGLENGTYKVEFETPSGYTPTQVGSGTDEGIDSNGTSTTGVIKDKDNDTIDSGFYKPTYNLGDYVWEDTNKNGVQDKDEKGISGVTVTLKDENDKVLKTVTTDENGKYQFTDLNNGTYKVEFETPSGYTPTSVTSGNDTEKDSNGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKDVKVILLNEKGEVIGTTKTDENGKYRFDNLDSGKYKVIFEKPTGLTQTGTNTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGKHTPVKPMSTTKDHHNKAKALPETGNENSGSNNATLFGGLFAALGSLLLFGRRKKQNK
What is the function of this protein?
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis.  Mediates interactions with components of the extracellular matrix such as host DSG1 to promote bacterial adhesion to host cells.  Contributes to the resistance to killing by innate immune components such as neutrophils present in blood and thus attenuates bacterial clearance.
What are the official names of this protein?
Serine-aspartate repeat-containing protein D.
What is the protein family that this protein belongs to?
Belongs to the serine-aspartate repeat-containing protein (SDr) family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor. Note=Anchored to the cell wall by sortase A (By similarity).
Protein: Y2275_STAAN
Sequence: MIHSRKLRLWLYLVLLAVFIGACGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKEGFRDEEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRNTRTTKGEFIVRELWEDKKGYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIEDFKFFVQYGDFKDINDYKDGDISYNPNVPSYSAKYQLSNNDYNVKQLRKRYDIPTKKAPKLLLKGDGDLKGSSIGHKNLEFIFIENKEENIYFTDSINFKPTE
What are the official names of this protein?
Uncharacterized lipoprotein SA2275.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.