PharMolix/UniProtQA huggingface dataset:
Protein: SYP_PHOPR
Sequence: MRTSNYLLSTLKETPNDAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLRKVENIVRQEIDNAGAVEILMPVVQPFELWEETGRSEKMGPELLRFTDRHSRPFVLSPTAEEVVTSLVRNEISSYKQLPLNLYQIQTKFRDERRPRFGVMRAREFSMMDAYSFDIDKEGLEKSYQAMHDAYCKAFDRMGLEYRPVLADSGAIGGSGSQEFHVLAESGEDLIAFSSDSDYAANIEKAEALAPTAELAAATQEMELVDTPNAKTIAELVEQHGLAIEKTVKTLFVKASDEIDADIVALIIRGDHELNEVKAENLPQVASPLEMAEEAEIRALIGAGPGSLGPVGLELPFIVDRTVAIMSDFGAGANVDGKHYFGINWGRDVELAQVEDLRNVVEGDLSPCGQGTIQLKRGIEVGHIFQLGTNYSKKMNCNVLGPDGKSATLEMGCYGIGVSRIVASAIEQNNDENGIIWPTALAPFQVAIVPMNMAKSEEVKAAAESLYAELTAAGIEVLFDDRKERPGVMFKDIELIGIPHTIVIGNRSLENGEMEYKDRRDGNKVAVPVADVVEMIKQKLA
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALIS2_ARATH
Sequence: MMEVEGSMNRAPDQSSFLRSRRSKALYQFKQQKLPACKPVLTPISVITVFMLMGFVFIPIGLITLRASRDAIEIIDRYDVECIPEEYRTNKLLYITDSSIPKNCTRYLKVQKYMKAPIFIYYQLDNYYQNHRRYVKSRSDQQLLHGLEYSHTSSCEPEESSNGLPIVPCGLIAWSMFNDTFTFSRERTKLNVSRNNIAWKSDREHKFGKNVYPINFQNGTLIGGAKLDPKIPLSDQEDFIVWMRAAALLSFRKLYGRIEEDLEPGKVVEVNLMNNYNTYSFSGQKKLILSTSNWLGGRNDFLGITYLVVGSSSIVISIIFMLLHLKNPRPYGDNSWNKKSLSS
What are the official names of this protein?
Putative ALA-interacting subunit 2, AtALIS2.
What is the protein family that this protein belongs to?
Belongs to the CDC50/LEM3 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: TPM03_CRAGI
Sequence: NSARGFDTVNEKYQECQTKMEEAEKTASEAEQEIQSLNRRIQLLEEDMERSEERLQTATEKLEEASKAADESERNRKVLENLNNASEERTDVLEKQLTEAKLIAEEADKKYDEAARKLAITEVDLERAEARLEAAEAKVLELEEELKVVGNNMKSLEISEQEASQREDSYEETIRDLTQRLKDAENRATEAERTVSKLQKEVDRLEDELLAEKERYKAISDELDQTFAELAGY
What is the function of this protein?
Tropomyosin, in association with the troponin complex, plays a central role in the calcium dependent regulation of muscle contraction.
What are the official names of this protein?
Tropomyosin, Allergen Cra g 1.03.
What is the protein family that this protein belongs to?
Belongs to the tropomyosin family.
Protein: GSPN_AERSA
Sequence: LQANRQYLFQGSLKPGPELPEEMKQGLPFLGQPDGQGRFPLRYQGRI
What is the function of this protein?
Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
What are the official names of this protein?
Type II secretion system protein N, T2SS protein N, General secretion pathway protein N.
What is the protein family that this protein belongs to?
Belongs to the GSP N family.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: PURNU_STAAM
Sequence: MNDNFKKQPHHLIYEELLQQGITLGITTRGDGLSDYPKNAFNMARYIDDRPYNITQHQLQLAEEIAFDRKNWVFPIQTHENKVACITKDDIGTNIDTLTDALHGIDAMYTYDSNVLLTMCYADCVPVYFYSTKHHFIALAHAGWRGTYTEIVKEVLKHVNFDLKDLHVVIGPSTSSSYEINDDIKNKFETLPIDSANYIETRGRDRHGIDLKKANAELLNYYGVPKENIYTTAYATSEHLELFFSYRLEKGQTGRMLAFIGQQ
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase SAV1187, Adenosine deaminase SAV1187, S-methyl-5'-thioadenosine phosphorylase SAV1187.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: RL1_METS3
Sequence: MTQEVLEAVKEAKEQSKPRNFTQSVDMIVNIRDLDVKKPENRFNEEVTLPNGRGKEVKIGVIADGELIVQAKDAGVALVINKADLEELGKDRKAAKKAANSVDFFIAQADMMPLVGRFLGPILGPRNKMPKPVPASIKLDPLLERLQSTVKVGIKQQPAIQIIVGSQDMSDEDLAENIETVLTVLDRHLDKGRNQIKSMFIKTTMGPIVRVI
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PETG_ARATH
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: FENR_STRGC
Sequence: MSELYDITIVGGGPVGLFAAFYAHLRQAKVKIIDSLPQLGGQPAILYPEKKILDVPGFTNLTGEELTQRLIEQLETFQTEICLNETVLDIVKGEEGFTITTSKAKHQTKTIIIAMGGGAFKPRALELDDAESYSNLHYHVSNINQYAGKKVVVLGGGDSAVDWALAFEKIAETSLVHRRDNFRALEHSVEELKASSVEIKTPFVPSRLVGENGKITHLEISQVKGEESQLLPLDHLFVNYGFKSSVGNLKNWGLELNRHKILVNSKQETSVPGIYAAGDCCSYEGKIDLIATGLGEAPTAVNNAINHIYPDQKVQPKHSTSL
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: TBB2A_HUMAN
Sequence: MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEAAGNKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETYSIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATADEQGEFEEEEGEDEA
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin beta-2A chain, Tubulin beta class IIa.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RAC3_ORYSJ
Sequence: MASSASRFIKCVTVGDGAVGKTCMLICYTSNKFPTDYIPTVFDNFSANVVVDSTTVNLGLWDTAGQEDYNRLRPLSYRGADVFVLAFSLVSRASYENIMKKWIPELQHYAPGVPIVLVGTKLDLREDKHYLLDHPGMIPVTTAQGEELRKQIGAAYYIECSSKTQQNVKGVFDAAIKVVIQPPTKQREKKKKKSRQGCSMMNMFRGRKMSCFKS
What is the function of this protein?
Inactive GDP-bound Rho GTPases reside in the cytosol, are found in a complex with Rho GDP-dissociation inhibitors (Rho GDIs), and are released from the GDI protein in order to translocate to membranes upon activation.
What are the official names of this protein?
Rac-like GTP-binding protein 3, OsRac3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Peripheral membrane protein. Note=Associated with the membrane when activated.
Protein: NDPA_ECO8A
Sequence: MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELHRVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGFVLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETNPESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADRSTLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGGN
What are the official names of this protein?
Nucleoid-associated protein YejK.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PURT_SALCH
Sequence: MTLLGTALRPAATRVMLLGAGELGKEVAIECQRLGIEVIAVDRYPDAPAMHVAHRSHVINMLDGEALRHVITEEKPHYIVPEIEAIATDTLRELEDEGLNVVPCARATQLTMNREGIRRLAAEELGLPTSTYRFADSEASFHDAVAAVGFPCIVKPVMSSSGKGQSFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQQDGDYRESWQPQQMSELALKRAQEIARHVVLALGGHGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGMPIGAIRQYGPAASAVILPQLTSQNVTFDDVHAAVGAGVQVRLFGKPEIDGTRRLGVALATGENVEEAVIRAKKAASRVTVKG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: SH3R1_HUMAN
Sequence: MDESALLDLLECPVCLERLDASAKVLPCQHTFCKRCLLGIVGSRNELRCPECRTLVGSGVEELPSNILLVRLLDGIKQRPWKPGPGGGSGTNCTNALRSQSSTVANCSSKDLQSSQGGQQPRVQSWSPPVRGIPQLPCAKALYNYEGKEPGDLKFSKGDIIILRRQVDENWYHGEVNGIHGFFPTNFVQIIKPLPQPPPQCKALYDFEVKDKEADKDCLPFAKDDVLTVIRRVDENWAEGMLADKIGIFPISYVEFNSAAKQLIEWDKPPVPGVDAGECSSAAAQSSTAPKHSDTKKNTKKRHSFTSLTMANKSSQASQNRHSMEISPPVLISSSNPTAAARISELSGLSCSAPSQVHISTTGLIVTPPPSSPVTTGPSFTFPSDVPYQAALGTLNPPLPPPPLLAATVLASTPPGATAAAAAAGMGPRPMAGSTDQIAHLRPQTRPSVYVAIYPYTPRKEDELELRKGEMFLVFERCQDGWFKGTSMHTSKIGVFPGNYVAPVTRAVTNASQAKVPMSTAGQTSRGVTMVSPSTAGGPAQKLQGNGVAGSPSVVPAAVVSAAHIQTSPQAKVLLHMTGQMTVNQARNAVRTVAAHNQERPTAAVTPIQVQNAAGLSPASVGLSHHSLASPQPAPLMPGSATHTAAISISRASAPLACAAAAPLTSPSITSASLEAEPSGRIVTVLPGLPTSPDSASSACGNSSATKPDKDSKKEKKGLLKLLSGASTKRKPRVSPPASPTLEVELGSAELPLQGAVGPELPPGGGHGRAGSCPVDGDGPVTTAVAGAALAQDAFHRKASSLDSAVPIAPPPRQACSSLGPVLNESRPVVCERHRVVVSYPPQSEAELELKEGDIVFVHKKREDGWFKGTLQRNGKTGLFPGSFVENI
What is the function of this protein?
(Microbial infection) Plays an essential role in the targeting of HIV-1 Gag to the plasma membrane, this function is dependent on it's RING domain, and hence it's E3 ligase activity.
What are the official names of this protein?
E3 ubiquitin-protein ligase SH3RF1, Plenty of SH3s, Protein POSH, RING finger protein 142, RING-type E3 ubiquitin transferase SH3RF1, SH3 domain-containing RING finger protein 1, SH3 multiple domains protein 2.
What is the protein family that this protein belongs to?
Belongs to the SH3RF family.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Cell projection, lamellipodium. Golgi apparatus, trans-Golgi network. Note=Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network.
Protein: PURA_PSYWF
Sequence: MGKNVVVLGSQWGDEGKGKIVDLLTEKASAVARFQGGHNAGHTLVVDGKKTVLHLIPSGILRDDVTCFIGNGVVLSPEALLIEMKELEDNNVPVRERLKISPNCPLIMPYHIALDQAREAKRGSGKIGTTGRGIGPAYEDKVARRAIKLADLFRPDLEEKLRNLIEYHNFQLTQYYKVDAIDFDTTFALCQQWRDELKELVCDVTEALNQLRLAGKNLMFEGAQGTLLDIDHGTYPFVTSSSVTAGGVSTGTGIGPLYLDYVLGITKAYTTRVGSGPFPTELFDDVGAHLAKVGHEFGATTGRARRCGWFDAEALRRAVVLNSLSGICLTKLDVLDGLDEIRIGVGYDIPESEFAAAHDGEFYETVTPKYETLPGWKGSTVGITNYDDLPEEAKAYIKRIEQLIDCPVDIISTGPDRDETIVLRDPYDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_AZOPC
Sequence: MAQINRKLYSSMYGITTGDIVTLGDTNLKIQVEKDYTTYGEECVFGGGKVIRDGMGQASGFCDEEVLDMVITNALIIDYKGIYKADIGIKNGKIKGIGKAGNPHIQPGVSPTLIIGTITEVVSGEGRILTAGAIDTHVHYISPQQADEALASGITTFVGGGTGPATGTYATTCTPGWYLRKMMEATDNIPINFGFLGKGNSSKSKALEGQIKAGALGLKLHEDWGSTPSVIDTSLKVADEYDVQICIHTDSINECGYIEDTLCAIDGRTIHAYHVEGAGGGHAPDIMKACEYANILPSSTTPTNPYSLNTIDEHLDMLMVCHHLDFNNPEDISFAQSRIRQQTIGAEDFLHDMGAISIFTSDSQAMGRIGEVICRTWQIASRMKEIRGFLSEDQMTGNDNYRVRRYIAKYTINAALAHGLSHIVGSVEKGKLADLVLWRPEFFGTKPDIVIKGGMIAYAQMGDPNASIPTPEPYISRPMYGAFGNAASATSCLFISEASIEAIKGYGLNKMLTVVKGCRVISKNDLKLNNYMPCIDIDSKTFEVSIDGVLISVKPAKKLPLAQLYNLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GUAAB_METTH
Sequence: MLNPSDFIEEAVEEIRSTVGNEKAIIALSGGVDSSVASVLAGRAIGDNLTAVFVDHGLLREGEAEYVRKTFSERLNFRYIDASEEFLKELEGVTDPEEKRKIIGRVFIEVFERVAEEIGARYLVQGTIAPDWIESEGQIKSHHNVALPHGLVLEIVEPIRELYKDEVREIGLELGLPREMIQRQPFPGPGLAVRIVGEITREKIEICRRANAIVEEEVVESGLHESLWQYFAVLTDTMVTGVKGDVRDFGYLVVIRMVESLDAMTASVPELPWDLIKRISKRITAEIPEVTHVALSVSDKPPSTIEFA
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing] subunit B, GMP synthetase.
Protein: GLMM_SALPK
Sequence: MSNRKYFGTDGIRGRVGNAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSASFTGPMPTPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDDVEEAIEAEMEKEITCVDSAELGKASRIVDAAGRYIEFCKGTFPNELSLNGLKVVVDCANGATYHIAPNVLRELGATVIAIGCEPNGVNINEEVGATDVRALQARVLVEKADLGIALDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKLQEKGWRIGAENSGHVILLDKTTTGDGIVAGLQVLAAMVRNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLENDAVKAVTADVEATLGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTAFAHRIADAVKAV
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RPOZ_BURO0
Sequence: MARITVEDCLKQIPNRFELALAATYRARQLAQGHTPKIESRDKPTVVALREIAAGQVGVEMLKKVPV
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: ERA_CAUVC
Sequence: MTDTTSKTRAGFAAIIGAPNAGKSTLVNRMVGAKVSIVTQKVQTTRFPVRGVAIEGDTQIVLVDTPGIFSPRRRLDRAMVRAAWAGSEEAEATVHLVDVQAELASRADKATPGEYRSAQDVQTIIEGLKAADRKVILALNKIDGIKRDTLLAVAKDFFDTGVYSDVFMISASTGAGVEDLTAKLVSMMPEGPWLYPEDQTADLPARLLAAEITREKVYLRVHEELPYAATVETTAFEERKDGSVRIEQTILVEREGQRVIVIGKGGQTLKWIGQASREELCDILDRKVHLFLHVKVKENWAEERGLFSDIGLDFDV
What is the function of this protein?
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange.  Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
What are the official names of this protein?
GTPase Era.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein.
Protein: FTSK_BIFLO
Sequence: MARTASSNSTKPRKSKDNGSTHDGETKVQPELDLEPEPLWKKILLAIPRAFGSGVRAVTGVGEYDPAYRRDGLCFLLLVLAVLFCASEWFRVSGPFGQLLHAIAAGVLGLMSVVLPVLLAAVAFRLMRNSGKGSNNPRVVTGWVLLMWSICSIIDVAIAADHTGFDITILQSAGGLFGFFLGSPLAWGLSNVFAIIIFVVVGLFSLLMITGTHVTDLPEDARKIAAKIQRKPYVPMGQETDGSASQFPNEVRVGDTTLAFADGVPSHDGDDDGSDNDQAGDARPSLFARLFGRKSKTEDDKTLDKYAADDPFDRAASQHGATAETPVVDPMTGEIIGARTIASSSYDGRPHLSSPAPAADADDGDASRTRVITSGQTVAMPGGGAVDDPWAPSAAQAGTVALAGAAGAMGAAGAAGAAAAAAATGAYAGADADGSGVGQGVPNTGGQPNATAGNDTDDDANRPYQLPDLNLLTKGQPHAMRTPANDRVIRALTSTFEQFNVDAKVVGFLRGPSVTQYEVELGPGVKVEKVTNLQRNIAYAVASSDVRILSPIPGKSAIGIEIPNEDREIVHLGDVLRSDKAVGDPNPMLSGIGKDVEGHFVTADLTKMPHLLVAGATGSGKSSFINSMLTSIIMRATPEQVRLIMVDPKRVELSAYAGIPHLLTPIITDPKKAAQALEWVVKEMDARYSDLEFFGFRHVKDFNEAVRAGKVHAPAGSQRKVAPYPYILVVVDEMADLMMVAKNDVESSIQRITQLARAAGVHLVLATQRPSVDVVTGLIKANIPSRLAFATSSATDSRVILDTVGAETLIGQGDALFLPMGSAKPIRVQGSWVSESEIRKAVEFVRTQRKPKYREDIEQMAKEAEKKDSMEPDEEIGDDMDVLLQAAELVVTSQFGSTSMLQRKLRVGFAKAGRLMDLLESRGVVGPSEGSKAREVLVQPQDLPQVLAFIRGETSSLEATAPQQPELGE
What is the function of this protein?
Essential cell division protein that coordinates cell division and chromosome segregation.  The N-terminus is involved in assembly of the cell-division machinery.  The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region.  Required for activation of the Xer recombinase, allowing activation of chromosome unlinking by recombination (By similarity).
What are the official names of this protein?
DNA translocase FtsK.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Located at the septum.
Protein: DEFI8_BOVIN
Sequence: MEYDEKLARFRQVHLNPFNKQQHEQGAGEEAPGITSQARLPELPPGEPEFRCPERVMDLGLSEDHFARPVGLFLASDVQQLRQAIQECKQVILDLPEHSEKQKDAVVRLIHLRLKLQELKDPNEDEPNIRVLLEHRFYKEKSKSVKQTCDKCNTVIWGLIQTWYTCTGCYYRCHSKCLNLISKPCVRSKVSHQAEYELNICPEAGLDSQDYRCAECRAPISLRGVPSEARQCDYTGQYYCSHCHWNDLAVIPARVVHNWDFEPRKVSRGSMRYLALMMSRPVLRLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCREAMAARLLLQLQDRQHFVENDEMYSVQDLLDTHTGRLGCSLAETHTLFAKHIKLDCERCQAKGFVCELCREGDVLFPFDSHTSVCADCSAVFHRDCYYDNSTTCPRCARLTLRKQSLFREPGPDLDA
What is the function of this protein?
Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts.  Involved in bone resorption.
What are the official names of this protein?
Differentially expressed in FDCP 8 homolog, DEF-8.
What is the protein family that this protein belongs to?
Belongs to the DEF8 family.
Protein: LDH_LACLN
Sequence: MKITSRKVVVIGTGFVGTSIAYSMINQGLVNELVLIDVNQDKAEGEALDLLDGISWAQENVIVRAGNYKDCENADIVVITAGVNQKPGQSRLDLVNTNAKIMRSIVTQVMDSGFDGIFVIASNPVDILTYVAWETSGLDQSRIVGTGTTLDTTRFRKELATKLEIDPRSVHGYIIGEHGDSEVAVWSHTTIGGKPILEFIVKNKKIGLEDLSNLSNKVKNAAYEIIDKKQATYYGIGMSTARIVKAILNNEQVILPVSAYLRGEYGQEGVFTGVPSVVNQNGVREIIELNIDAYEMKQFEKSVSQLKEVIESIK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase, L-LDH.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPE_COLP3
Sequence: MALLTVNLNVVSAEESLFSGSIKSLQITGSEGELGIMPGHAPLLTSLKPGMALITKADGTEEVIYLSGGMLEVQPNNVTVLADVATRAADLDEEAALAAKQRAEDNMNAHGGDVDYAAVAAELARAVAQLRVIQATSKHS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PTH_VIBC3
Sequence: MSQPIKLLVGLANPGPEYAKTRHNAGAWVVEELARIHNVTLKNEPKFFGLTGRLLINSQELRVLIPTTFMNLSGKAIAALANFYQIKPEEIMVAHDELDLPPGVAKFKQGGGHGGHNGLKDTISKLGNNKEFYRLRLGIGHPGHKDKVAGYVLGKAPAKEQECLDAAVDESVRCLEILMKDGLTKAQNRLHTFKAE
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_SYNR3
Sequence: MSHRLLFVGPPGAGKGTQAERLAANHGLLHLSTGDLLRAEVKAGSELGKEAEAVMNRGELVSDALVLAIVRSRLQSHSGGWLLDGFPRNLAQAEALDALLSELNQPLQSVLLMELDDDELVQRLLARGRADDNEEVIRHRLSVYREQTAPLINHYEQRGQLKRVVSTGTIEAVAEQITAALA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NKG2F_PANTR
Sequence: MNKQRGTYSEVSLAQDPKRQQRKLKGNKSSISGTKQEIFQVELNLQNASSDHQGNDKTYHCKGLLPPPERLTAEVLGIICIVLMATVLKTIVLIPCIGVLEQNNFSLNRRMQKACDCGHCPEEWITYSNSCYYIGKERRTWEEGVCWPVLQRTLICFL
What is the function of this protein?
May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells.
What are the official names of this protein?
NKG2-F type II integral membrane protein, NK cell receptor F, NKG2-F-activating NK receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: RECO_ALISL
Sequence: MEEGLQRCFVLHRRPYSESSLILDVFSEEYGRLSIISKGARSKRSNLKGVLQAFTPLLMKWSGKGSMRTLRQAETISLAIPLTGINLYSALYINELVVRVIEQETPYPALFLDYLTALTELAQTKNPEPALRRFELALLSSLGYGVDFLHCAGSGEMVSPEMTYRYREQKGFMASIRHDPLMSFKGDELIAISERRFITPEQLKAAKRFTRIALKPYLGGKPLKSRELFLPRTRSILK
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: GCSH_EDWI9
Sequence: MSNVPTELKYTASHEWVRAEENGVFCVGITDHAQSLLGDMVFVDLPEVGAHIDTGAECAVAESVKAASDIYSPLAGEIVAINGSLEEAPEQVNAAPYDEGWLFRIRADDPAEFAALLSAEGYLAALDE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: CPFC2_BACAN
Sequence: MKKKKIGLLVMAYGTPDSLDEVEAYYTHIRHGRKPSEEALQDLIGRYKAIGGISPLAKITKEQAHKLTDSMNNMFTEYEFNCYLGLKHTAPFIEDAVEEMKRDGIEQAISIVLAPHYSTFSIKAYNERAIRLSEEIGGPVIKPIDQWYDEPKFISYWADQIKETFTKIEDKEKAVVIFSAHSLPEKIIAAGDPYVEQLQHTADLIAAAANIQNYTIGWQSAGNTPDPWIGPDVQDLTRDLFEEYRYESFIYCPVGFVAEHLEVLYDNDYECKVVTDELNAAYFRPNMPNAQSTFIDCLATIVSRKMKEIVDKELILNNN
What is the function of this protein?
Involved in coproporphyrin-dependent heme b biosynthesis.  Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.
What are the official names of this protein?
Coproporphyrin III ferrochelatase 2.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.