PharMolix/UniProtQA huggingface dataset:
Protein: PSBA_TETOB
Sequence: MTAILAKNEASSLWARFCEWITSTENRLYIGWFGVIMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAVVPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFFLGICCYMGREWELSYRLGMRPWIAVAYSAPVAAATAVFIIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANEGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVLNTWADIINRANLGMEVMHERNAHNFPLDLASVEAPSVNA
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ORF3_HEVCT
Sequence: MEMPPCALGLFCFCSSCFCLCCPRHRPVSRLAVAAGKRGAAVVSGVTGLILSPSPSPIFIQPTPSHLTFQPPPGLELALGSQSVHSAPLGVTSPSAPPLPPVVDLPQLGLRR
What is the function of this protein?
Small multifunctional phosphoprotein involved in virion morphogenesis, egress and counteracting host innate immunity.  Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway.  Acts also as a viroporin and forms ion conductive pores allowing viral particle release.  Impairs the generation of type I interferon by down-regulating host TLR3 and TLR7 as well as their downstream signaling pathways.  Down-regulates the phosphorylation of host IRF3 via the interaction with host SIRP-alpha, thereby inhibiting IFN-I expression.  Interacts with host microtubules.
What are the official names of this protein?
Protein ORF3, pORF3.
What is the protein family that this protein belongs to?
Belongs to the hepevirus ORF3 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The N-terminal region seems to associate with the cytoskeleton probably via one of its hydrophobic regions.
Protein: LPTD_VIBVU
Sequence: MQHFSRTFLAASIATALFAPYAQAEAILNNSVQEMPTTDQCLVDAEKNDANAEIVIQADNLQAINGDKAIYSGDVEVTQGNKKITAESVTLHQQENIVVAEGNVTFNDGEVKASSSKVTNNMTSETFSLENTEYQFLCQQGRGQAAYIAKTGQAVYELEDGSITSCPADDNAWRLVASSIEVDQNEETATFYHPRFEVLDVPVFYAPYLTLPIGNTRKTGFLFPSVNYGSSDGLEIEVPFYWNIAPNYDLTLTTLYMQQRGVKQDADFRYLSDGWGAGELKGEYLPGDEKYNDEDRWGYQYKHDGIINKQWLVSLDYSQVSDIDYFRDLSSDLGNREDGQLMQQGKVAYRSDFWDMSLQVRDFQILLQDNNQPYRLLPQVKFNFYTPLLGNYLNFDVKSELTQFDIQDASKPNALRAHVEPGLTIPLSTSWATWTTEARLLATYYQQDLDRLTDPTLKSQLDETVARVIPEYRSHARIYLEREAKLFEGYTQSLEPQIQYLYVPEEEQGNIYNYDTTLLQTDYYGLFRSRKYSSIDKIAAANQLSYGASTRFFDDEYKERLNISFGQIYYIDKKTKLTGNQEETSNYSSWAVETDFNYEDFLFYHGGIQYDIDLNAMQLANSTLEYQFTDGFIQGNYRYVTKDYIEDTISFDELDKITRKGISQAGIVGAYNINRHWSASGQYYYDLTEEIDLEWMASLRYQSDCWYIGFTYTNQLVKWRNDVVGGDSNNPVYDTNISVNFGIQGFATKNKAETAAKELDSTDNAITYGRPFYLNN
What is the function of this protein?
Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
What are the official names of this protein?
LPS-assembly protein LptD.
What is the protein family that this protein belongs to?
Belongs to the LptD family.
What are the subcellular locations of this protein?
Cell outer membrane.
Protein: CYB6_ARATH
Sequence: MSKVYDWFEERLEIQAIADDITSKYVPPHVNIFYCLGGITLTCFLVQVATGFAMTFYYRPTVTEAFASVQYIMTEANFGWLIRSVHRWSASMMVLMMILHVFRVYLTGGFKKPRELTWVTGVVLGVLTASFGVTGYSLPWDQIGYWAVKIVTGVPDAIPVIGSPLVELLRGSASVGQSTLTRFYSLHTFVLPLLTAVFMLMHFLMIRKQGISGPL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: VIF_FIVT2
Sequence: MSDEDWQVSRRLFAVLQGGVYSAMLYISSLPEMEQDKCKRSFKKRLSEKETGFIFRLRKAEGIRWSFHTRDYYIGYVREMVAGSSLPDSLRLYVYISNPLWHQSYRPGLTNFNTEWPFVNMWIKTGFMWDDIESQNICKGGEISHGWGPGMVGIVIKAFSCGERKIKITPVMIIRGEIDPTEWCGDCWNLMCLKYSPPNTLQRLAMLACGKEAKEWRGCCNQRFVSPFRTPCDLEVVQNKPKRNLLWTGEL
What is the function of this protein?
Determines virus infectivity.
What are the official names of this protein?
Virion infectivity factor.
What is the protein family that this protein belongs to?
Belongs to the feline lentivirus group Vif protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: SSRP_STAA2
Sequence: MAKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGSANLKDSYAQVKNGEMYLNNMHIAPYEEGNRFNHDPLRSRKLLLHKREIFKLGEQTREIGYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVKRDVARDMKARY
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: GATC_RHOCS
Sequence: MSLDKATVAKIAHLARIRVPEEEQEHLAQELNGILGWVEQLGEVDTDGVQPITSNVAQTLRRRQDVVTDGGYPEKVVANAPEGAEHFFAVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: YJGA_SHIB3
Sequence: MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKEGNKPPKSARQIFQYLRELAENEE
What are the official names of this protein?
UPF0307 protein YjgA.
What is the protein family that this protein belongs to?
Belongs to the UPF0307 family.
Protein: PP4RL_HUMAN
Sequence: MAEIPLYFVDLQDDLDDYGFEDYGTDCDNMRVTAFLDIPGQDNLPPLTRLEKYAFSENTFNRQIIARGLLDIFRDFGNNEEDFLTVMEIVVRLSEDAEPTVRTELMEQIPPIAIFLQENRSNFPVVLSEYLIPIVVRYLTDPNNQIICKMASMLSKSTVERLLLPRFCELCGDRKLFQVRKVCAANFGDICHAVGQEATEKFLIPKFFELCSDAVWGMRKACAECFTAVSHSSSPGVRRTQLFPLFIRLVSDPCRWVHQAAFQSLGPFTSTFANPSRAGLYLREDGALSIWPLTQDLDSGFASGSPAPSSGGNTSPASLTRSAKPVRSEPELPVEGTSAKTSDCPHSSSSSDGPAESPVESCVSAGAEWTRVSPETSACSKLSDMNDLPISSYPGSDSWACPGNTEDVFSHFLYW
What is the function of this protein?
May be a regulatory subunit of serine/threonine-protein phosphatase 4.
What are the official names of this protein?
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like.
Protein: RNFE_PASMU
Sequence: MDQQSTLANTSTPSVWKTLFWQGVWKNNSTLVQLLGLCPLLAVSNSVTNALGLGIATLFVLICSNTVVSLFRKQIPHEIRIPIYVMIIATTVTVVQLLMNAYTYSLYQSLGIFIPLIVTNCIVIGRAEAFASKNPLSHAMFDGFAMGLGMCLSLVFLGAIREILGNGTLFDGIEHLLGDWAKGLRIELFHLDSHFLLAILPPGAFIGLGLILAIKNVIDQRNKA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit E, Rnf electron transport complex subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOA_THEFY
Sequence: MLIAQRPTLTEEPISEFRSKFILEPLEPGFGYTIGNSLRRTLLSSIPGAAVTSIRIEGVEHEFTTVPGVKEDVTEIILNLKGLVVSSEHDEPVLMYLRKQGPGVVTAADIAPPAGVEVHNPEMHIATLNSKGKLEMEMTVERGRGYVSAAQNKQPGQEIGRIPIDSIYSPVMRVTYKVEATRVEQRTDFDRLILDVWTKPAIRPRDAVASAGKTLVELFGLARELNVDAEGIDMGPSPTDAALAADLALPIEDLNLTVRSYNCLKREGIHTVGELVARTEQDLLDIRNFGAKSIEEVKQKLSDMGLALKDAQGGFDPGSAAGSYGSDHDQSYVETEQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RL28_GRAFK
Sequence: MSRVCELTGKRAMVGNNVSHAMNKTKRKFNANLVKKRFFLPEEDRWVTLKVCTSALKDINKKGISAVIKEAKAKGFLQK
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: M4H37_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGLAKVLAEKYANGKRTAEDHEVMKRLEAIMRDLDSLDYPEEASERETRGFNQDEIAKEKRILGPVLGLVGNALGGLIKKIG
What is the function of this protein?
Maximin-H3 shows antibacterial activity against both Gram-positive and Gram-negative bacteria.  It shows also antimicrobial activity against the fungus C. albicans.  Shows strong hemolytic activity.
What are the official names of this protein?
Maximins 4/H3 type 7.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PERL_MESAU
Sequence: MKVLLRLPALLASLTLLQMAASTRNATRTATIRETVDEVKVQVNKAFLDSRDRLKTDMSNLAPTVRHLSGYLKQAKGRTRTAIRVGQVWEQSLKRLRRMVPLTNVTGQGLDLTSLSWEVGCGHPAPTVTCNISNPYRTITGDCNNRKNPELGSANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPQPRDVSNQVLDYLNEEEILDQNRSLLFMQWGQIVDHDLDFAPETEMGSDNYSKAQCDELCIQGDNCFPIMFPKGDPKLKTQGKCLPFFRAGFVCPTSPYQSLAREQINALTSFMDASMVYGSEPSLANRLRNLSSPLGLMAVNEEVSDHGRPLLPFVNVKPSPCEVINRTAGVPCFLAGDSRASEQILLATSHTLFLREHNRLARELSRLNPQWDGEKLYQEARRIMGALIQIITFRDYLPILLGDELQKWIPPYQGYKETVDPRISNVFTFAFRFGHLEVPSTVSRLDENYQPWGSEPELPLHKLFFNTWRVVKDGGIDPLVRGLLAKKAKLAHQDKMMTGELRNMLFQPNHTVHGFDLAAINIQRCRDHGQPGYNSWRAFCGLSQPKTLEELSAVLRNEVLAKKLMDLYGTPDNIDIWLGAIAEPLVRRGRVGPLLTCLLGQQFQRIRDGDRFWWENPGVFTEKQRDSLQKMSFSRLVCDNTGINKVPLNPFQPNSYPHSFVDCSAIEKLDLTPWASVKK
What is the function of this protein?
Heme-containing oxidoreductase which catalyzes the conversion of thiocyanate (SCN(-)) into antimicrobial agent hypothiocyanous acid (OSCN(-)) in the presence of hydrogen peroxide (H2O2).  Also involved in the conversion of iodide (I(-)) into hypoiodite (IO(-)) in the presence of H2O2 (By similarity).  Responsible for the inactivation of a wide range of micro-organisms and hence, important component of defense mechanism.  May be implicated in airway host defense against infection (By similarity).  May contribute to maintaining an appropriate H2O2 cellular level, therefore protecting cells from H2O2-caused injuries and inflammation (By similarity).
What are the official names of this protein?
Lactoperoxidase, LPO, Lacrimal gland peroxidase.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. XPO subfamily.
What are the subcellular locations of this protein?
Secreted. Cytoplasm. Note=Secreted by the lacrimal gland into tears.
Protein: O5AK2_HUMAN
Sequence: MTLGNSTEVTEFYLLGFGAQHEFWCILFIVFLLIYVTSIMGNSGIILLINTDSRFQTLTYFFLQHLAFVDICYTSAITPKMLQSFTEEKNLMLFQGCVIQFLVYATFATSDCYLLAMMAVDPYVAICKPLHYTVIMSRTVCIRLVAGSYIMGSINASVQTGFTCSLSFCKSNSINHFFCDVPPILALSCSNVDINIMLLVVFVGSNLIFTGLVVIFSYIYIMATILKMSSSAGRKKSFSTCASHLTAVTIFYGTLSYMYLQSHSNNSQENMKVAFIFYGTVIPMLNPLIYSLRNKEVKEALKVIGKKLF
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 5AK2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PHR4A_XENLA
Sequence: MEDRSEEGGDHSEMPSAPSTPPSKRKSKFAGFGKFFKPWKWRKRKSSDSFRETSEVLERKISTRKPREELIKRGLLVEVPEEDGSIPSESPPLRNGHMSVEPANPPEDSGGLKRKTRPDSTGPRPKSGETTVQPCATAEVAPLEPHATAEVSPVQPQASAEVTPVQPLPVSEVAPMQPLPVNEVAPMQPLPVNEVAPKQPHHVSEVASVVSRPTSEVAPVQKVSRDFSKQPLLPPKRPLSISTSVTQESAVAGQKSDSSNRLQSSAPVPTPRTIHPPASSKQPPVPPPKPQNRNSNPLMAELSLALAGSPLSPAGSRPSPPLPPKRAMPPSTDAVTNKENALGPASLPPTPANEIITPSPPSPPASSHIPVSNPPVPPLTLAPPYTEVEKEQSASPIPLHIRIQQALNSPQPLPLLDSSQRAQSLLFMQNDMGPSEEGTRVRSLPVTIELLKVPDDEDDESLEDESLSPESSESHTSKVYIGDVPSVTVIPSYLPTCVQEEEEGGVSDTDSEGPVLYRDDEEEEEEEETSALANKVKRKDTLAMKLSGRMASEDSNSEFPQRSREEWNQIRQDIGTQLNRRLSQRPTAEELEQRNILQKNEADRLAEKKEIKRRLTRKLSQRPTVAELVERKILRFNEYVEATDAHDYDRRADKPWTRLTPADKAAIRKELNEFKSTEMAVHAESKHFTRFHRP
What is the function of this protein?
Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development.  Acts as an activator of PP1.  During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina.  Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway (By similarity).
What are the official names of this protein?
Phosphatase and actin regulator 4-A.
What is the protein family that this protein belongs to?
Belongs to the phosphatase and actin regulator family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, lamellipodium.
Protein: MDM10_YEAS6
Sequence: MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIHLQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLENFMRNSTDIPLQDATETYRQLQPNLNFSVSSGNTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLNPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDINSNSRATKLLHENVPDLNLAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRKIDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTRGFQESLSDDEKNDNAISISATDTENGNIPVFPTKFGIQFQYST
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: DNAA_PROM5
Sequence: MQATNPIWAEVQQLLQKNLSKPSFETWIRPAKFNCFENGLLTLITPNNFTSDWLRKNYSETIEKAAEEICGHNVKVIFKSENNVNNNSNIPDTVSQQSIKSQTRSISTSQGNNTNNRTKKSHSLNIRYVFKRFVVGPNSRMAHAAALAVAESPGREFNPLFICGGVGLGKTHLMQAIGHYRVEIDPEAKVLYVSTETFSSDLIQSIRKDGMHVFKNKYRSVDLLLIDDIQFLEGKEYTQEEFFNTFNALYEAGKQIVIASDRPPSQIPKLQERLISRFSMGLIADIQPPDIETRMAILQKKAEQERMNLPRDLVQFIAGRFSSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVIKKVSDFFSVTAEELVSSSRRKPVSQARQIGMYLMRQGTNLSLPKIGDEFGGKDHTTVMYAIEQVEKKLSSDPNVASQVQKIKDLLQIDSRKNL
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSHC_ARATH
Sequence: MEIAISYKPNPLISSSTQLLKRSKSFGLVRFPAKYGLGATRKKQLFRVYASESSSGSSSNSDGGFSWVRLAQSIRLGAERIGEKIGESVKTEIGFDSEEASGRVNEYVARVKDSVHKGHHELTRFKNETVPSFIDWNKWEHWKDIRNWDGKRVAALFIYAFALLLSCQRVYVAIQAPRVERERRELTESFMEALIPEPSPGNIEKFKRNMWRKATPKGLKLKRFIEAPDGTLVHDSSYVGENAWDDDLETTEGSLKKIIGRNARIQTEAKKKLSQDLGVSGEIGDSVGNWRERLATWKEMLEREKLSEQLNSSAAKYVVEFDMKEVEKSLREDVIGRTSETEGTRALWISKRWWRYRPKLPYTYFLQKLDSSEVAAVVFTEDLKRLYVTMKEGFPLEYIVDIPLDPYLFETICNAGVEVDLLQKRQIHYFMKVFIALLPGILILWFIRESAMLLLITSKRFLYKKYNQLFDMAYAENFILPVGDVSETKSMYKEVVLGGDVWDLLDELMIYMGNPMQYYEKDVAFVRGVLLSGPPGTGKTLFARTLAKESGLPFVFASGAEFTDSEKSGAAKINEMFSIARRNAPAFVFVDEIDAIAGRHARKDPRRRATFEALIAQLDGEKEKTGIDRFSLRQAVIFICATNRPDELDLEFVRSGRIDRRLYIGLPDAKQRVQIFGVHSAGKNLAEDIDFGKLVFRTVGFSGADIRNLVNEAAIMSVRKGRSYIYQQDIVDVLDKQLLEGMGVLLTEEEQQKCEQSVSYEKKRLLAVHEAGHIVLAHLFPRFDWHAFSQLLPGGKETAVSVFYPREDMVDQGYTTFGYMKMQMVVAHGGRCAERVVFGDNVTDGGKDDLEKITKIAREMVISPQSARLGLTQLVKKIGMVDLPDNPDGELIKYRWDHPHVMPAEMSVEVSELFTRELTRYIEETEELAMNALRANRHILDLITRELLEKSRITGLEVEEKMKDLSPLMFEDFVKPFQINPDDEELLPHKDRVSYQPVDLRAAPLHRS
What is the function of this protein?
Probable ATP-dependent zinc metallopeptidase.
What are the official names of this protein?
ATP-dependent zinc metalloprotease FTSH 12, chloroplastic, AtFTSH12.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the peptidase M41 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein; Stromal side.
Protein: Y219_BARQU
Sequence: MRDMMSMMKKAKEIQEKMQQIQEEMTNLQMIGTAGGGLINVTLNGKNTITAIKIDPSLLKPEESEILEDLIMAAHNDAKTKIEIAMEEKTKSMTAGLPLPSGFKFPFS
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BQ02190.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: AGAL_THEMA
Sequence: MEIFGKTFREGRFVLKEKNFTVEFAVEKIHLGWKISGRVKGSPGRLEVLRTKAPEKVLVNNWQSWGPCRVVDAFSFKPPEIDPNWRYTASVVPDVLERNLQSDYFVAEEGKVYGFLSSKIAHPFFAVEDGELVAYLEYFDVEFDDFVPLEPLVVLEDPNTPLLLEKYAELVGMENNARVPKHTPTGWCSWYHYFLDLTWEETLKNLKLAKNFPFEVFQIDDAYEKDIGDWLVTRGDFPSVEEMAKVIAENGFIPGIWTAPFSVSETSDVFNEHPDWVVKENGEPKMAYRNWNKKIYALDLSKDEVLNWLFDLFSSLRKMGYRYFKIDFLFAGAVPGERKKNITPIQAFRKGIETIRKAVGEDSFILGCGSPLLPAVGCVDGMRIGPDTAPFWGEHIEDNGAPAARWALRNAITRYFMHDRFWLNDPDCLILREEKTDLTQKEKELYSYTCGVLDNMIIESDDLSLVRDHGKKVLKETLELLGGRPRVQNIMSEDLRYEIVSSGTLSGNVKIVVDLNSREYHLEKEGKSSLKKRVVKREDGRNFYFYEEGERE
What is the function of this protein?
Hydrolyzes the short-chain alpha-galactosaccharides raffinose, melibiose and stachyose.
What are the official names of this protein?
Alpha-galactosidase, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 36 family.
Protein: MELK_HUMAN
Sequence: MKDYDELLKYYELHETIGTGGFAKVKLACHILTGEMVAIKIMDKNTLGSDLPRIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPELIQGKSYLGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLRLSSFSCGQASATPFTDIKSNNWSLEDVTASDKNYVAGLIDYDWCEDDLSTGAATPRTSQFTKYWTESNGVESKSLTPALCRTPANKLKNKENVYTPKSAVKNEEYFMFPEPKTPVNKNQHKREILTTPNRYTTPSKARNQCLKETPIKIPVNSTGTDKLMTGVISPERRCRSVELDLNQAHMEETPKRKGAKVFGSLERGLDKVITVLTRSKRKGSARDGPRRLKLHYNVTTTRLVNPDQLLNEIMSILPKKHVDFVQKGYTLKCQTQSDFGKVTMQFELEVCQLQKPDVVGIRRQRLKGDAWVYKRLVEDILSSCKV
What is the function of this protein?
Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation.  Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622.  Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1.  Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis.  Plays a key role in cell proliferation and carcinogenesis.  Required for proliferation of embryonic and postnatal multipotent neural progenitors.  Phosphorylates and inhibits BCL2L14, possibly leading to affect mammary carcinogenesis by mediating inhibition of the pro-apoptotic function of BCL2L14.  Also involved in the inhibition of spliceosome assembly during mitosis by phosphorylating ZNF622, thereby contributing to its redirection to the nucleus.  May also play a role in primitive hematopoiesis.
What are the official names of this protein?
Maternal embryonic leucine zipper kinase, hMELK, Protein kinase Eg3, pEg3 kinase, Protein kinase PK38, hPK38, Tyrosine-protein kinase MELK.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
Protein: RL15_WOLPM
Sequence: MNNAVKLNSIFTKLSKKKKPKLLGRGIGCGKGKTSGRGHKGQKARSGVSINGFEGGQQSIYTRLPKRGFKPIRRSIYSIINVGDIQRLMEAKKIVKDSVIDKERLYKLGFIKSIKDKIKLLNKGKLSEKFVFHVDFASEAAKKSVASVGGSVEILS
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: CLPP_BURMA
Sequence: MASQAPRDFEAQALGLVPIVVETSGRGERSYDIYSRLLKERIVFMVGEVNDQTANLVVAQLLFLESENPDKDISLYINSPGGSVSAGMAIYDTMQFVKPDVSTLCMGLAASMGAFLLASGAKGKRYALPNARVMIHQPLGGARGQASDIEIQAREILYLRDRLNHLLAHHTGQDVERIARDTDRDNFMSSEDAKAYGLIDHVSTKRP
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCGN_SALTI
Sequence: MADTLMSDTPFWQRKTLDEMTDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRHYERRFEFEPDCIKLTRENLPDFEWLPMTCAYRLLAEGKPLPTWHPLQTGSKAAMHGERISVRHIAVKESEVRDWQDHILNKPSWAE
What are the official names of this protein?
UPF0260 protein YcgN.
What is the protein family that this protein belongs to?
Belongs to the UPF0260 family.