PharMolix/UniProtQA huggingface dataset:
Protein: HMT1_BRAOT
Sequence: MGLEKKSALLEDLIEKCGGCAVVDGGFATQLEIHGAAINDPLWSAVSLIKDPELIKRVHMEYLEAGADVVVTSSYQATIPGFLSRGLSMEESESLLQKSVKLAVEARDRFWDKVSKTSGHSYNRALVAASIGSYGAYLADGSEYSGSYGEDVSLDKLKDFHRRRIQVLVEASPDLLAFETIPNKLEAQACVELLEEENVQIPAWICFTSVDGENAPSGESFQECLETLNKSNNICAVGINCAPPQFMDNLIRKFSKLTQKAIVVYPNSGEVWDGKAKKWLPSQCFGDAEFEMFATKWRDLGAKLIGGCCRTTPSTIKAISRDLKRR
What is the function of this protein?
Catalyzes methyl transfer from S-methylmethionine to homocysteine.  The highest preference is for DL-homocysteine >> DL-cysteine.  Has no selenocysteine methyltransferase activity.
What are the official names of this protein?
Homocysteine S-methyltransferase 1, BoHMT1.
Protein: RL33_LACCB
Sequence: MRNNIILGNNETGERIYLTSKNKRNTPDRLQLKKYSPKLRKRVVFTEVK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: SLAP_AERSA
Sequence: MFKKTLIAAAIVVGSAAPAFADVVISPNDNTFVTTSLASVTKQPVLDFSTAQQNLTLNFSEVGDLKNNGFIVLEIQGEGQFNDAEIRQWLSNGFWRRPFTGLLVNPNDHGNFANSGEVNDVRKFFKIISDGTQLTIVHTIDSNGKRLRLALASDVEETINFADAEVELKLNLANQAFKLTSGSQGTVALTAGALWNASYTADPVATKPLFKLGKLFQLSLTNAGKATALVSEGFLKLNIGDANISATDFAITNVTTNQTIQRDKVNLTLTGDVSAFKKDANGNLVNKAGASIGWKAAADGQSATAVLGAGNMAGGVQNALAAFGTLYVAADNTVPVPAVNFNVKAEIQGDSQATYNYFKDELADLFILTRDGMKFDTITTGTTSANLIHIRDVSNILPTEGGKIFVTITEYADHAANGRGEGTVLVTRKALSVTLPSGGAVTLKPADVAADVGASITAGRQARLVFEVETNQGEVAVKKSNAEGVDIQNGTRGTAPLVDFTL
What is the function of this protein?
S-layer protein.  The S-layer is a paracrystalline mono-layered assembly of proteins which coats the surface of bacteria.  This S-layer, also called A-layer, confers virulence to the bacterium infecting salmonid and non-salmonid fish.  It binds specifically to laminin and fibronectin.
What are the official names of this protein?
S-layer protein, A-layer protein, Cell surface virulent A protein, A-protein, Tetragonal surface virulence array protein.
What are the subcellular locations of this protein?
Secreted, cell wall, S-layer. Note=This bacterium is covered by a S- layer with tetragonal symmetry. Tethered to the outer membrane by interaction with O-side chain of the LPS.
Protein: THIE_LIMRJ
Sequence: MIFDPKMLQVYLVGGTQDVHNDVVKFLEKVELAMKSGITAFQYREKGNSKLRPNERVDLGLELRTLCTHYGIPLIVDDDYELAQQINADGVHVGQNDTKIEQVSVAVGHQMFIGYSCNTPEQVERANTMDFIDYIGCGPVFPTKSKSDADTAIGINRLERLNMISERPVVAIGGIDEENMKVVHDTGVAGLAVISLVFDSKDLVATVKKMKNLYK
What is the function of this protein?
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).
What are the official names of this protein?
Thiamine-phosphate synthase, TP synthase, TPS, Thiamine-phosphate pyrophosphorylase, TMP pyrophosphorylase, TMP-PPase.
What is the protein family that this protein belongs to?
Belongs to the thiamine-phosphate synthase family.
Protein: MAN12_PENCI
Sequence: MRLPVSFPLTVLSLLGSTIAHPYGETEAVLRSEPKSNQAKADAVKEAFQHAWNGYMKYAFPHDELTPVSNGHADSRNGWGASAVDALSTAVIMGKADVVNAILEHVADIDFSKTSDTVSLFETTIRYLAGMLSGYDLLQGPAKNLVDNQDLIDGLLDQSRNLADVLKFAFDTPSGVPYNNINITSHGNDGATTNGLAVTGTLVLEWTRLSDLTGDEEYAKLSQKAESYLLKPQPSSSEPFPGLVGSSININDGQFADSRVSWNGGDDSFYEYLIKMYVYDPKRFETYKDRWVLAAESTIKHLKSHPKSRPDLTFLSSYSNRNYDLSSQHLTCFDGGSFLLGGTVLDRQDFIDFGLELVDGCEATYNSTLTKIGPDSWGWDPKKVPSDQKEFYEKAGFYISSGSYVLRPEVIESFYYAHRVTGKEIYRDWVWNAFVAINSTCRTDSGFAAVSDVNKANGGSKYDNQESFLFAEVMKYSYLAHSEDAAWQVQKGGKNTFVYNTEAHPISVARN
What is the function of this protein?
Involved in the maturation of Asn-linked oligosaccharides.  Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
What are the official names of this protein?
Mannosyl-oligosaccharide alpha-1,2-mannosidase, Man(9)-alpha-mannosidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 47 family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDPC_RHILO
Sequence: MLKQIRPAIVMIVFFTVLTGLVYPLGMTGIAQALFPRQANGSLIEKDGKVIGSELIGQAFASDKYFHGRPSAAGNGYDAGASGGSNLGPTNPKLIERIKGGAEKLKAENPNQPVPMDLVTTSGSGLDPQISPEAAYFQVPRVAKARGIDEAKVKALVDGQVEGRELGFMGEPVVNVLALNLALDAAK
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
What are the official names of this protein?
Potassium-transporting ATPase KdpC subunit, ATP phosphohydrolase [potassium-transporting] C chain, Potassium-binding and translocating subunit C, Potassium-translocating ATPase C chain.
What is the protein family that this protein belongs to?
Belongs to the KdpC family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: NCAP_PI1HW
Sequence: MAGLLSTFDTFSSRRSESINKSGGGAIIPGQRSTVSVFILGPSVTDDADKLLIATTFLAHSLDTDKQHSQRGGFLVSLLAMAIRSPELYLTTNGVNADVKYVIYNIERDPKRTKTDGFIVKTRDMEYERTTEWLFGPMINKNPLFQGQRENADLEALLQTYGYPACLGAIIVQVWIVLVKAITSSAGLRKGFFNRLEAFRQDGTVKSALVFTGDTVEGIGAVMRSQQSLVSLMVETLVTMNTSRSDLTTLEKNIQIVGNYIRDAGLASFMNTIKYGVETKMAALTLSNLRPDINKLRSLVDIYLSKGARAPFICILRDPVHGEFAPGNYPALWSYAMGVAVVQNKAMQQYVTGRTYLDMEMFLLGQAVAKDADSKISSALEEELNVTDTAKERLRHHLTNLSGGDGAYHKPTGGGAIEVAIDHTDITFGAEDTADRDNKNWTNNSNERWSNHSINNHTITISGAEQLEEETNDEDITDIENKIARRLADKKQRLSQANNKQDANSDADYENDDDATAAAGIGGI
What is the function of this protein?
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases.  The nucleocapsid (NC) has a helical structure.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, NP, Protein N.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses nucleocapsid family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: SECA_RHOPS
Sequence: MIGAFARKLFGSSNDRRIKAYQARVAAINALEPDVAALSDEALRARTDQFRAELAAGKTLDDLLIPAFATVREAAKRTLGQRHFDVQLIGGMVLHEGDIAEMKTGEGKTLVATLACYLNALAGKGVHVVTVNDYLASRDAGWMGQIYAFLGMSTGVIVHGLDDSQRQKAYACDITYGTNNEYGFDYLRDNMKYRLEDMAQRGHFFAIVDEVDSILIDEARTPLIISGPLDDRSEFYNTIDTFIPRLDKSDYDVDEKQRSVALTEAGMEKIETLLRDAGQLKGESLYDIENVSVVHHINQALRAHTLFQRDKDYIVRNDEVVIIDEFTGRMMQGRRYSEGLHQALEAKEHVTVQPENQTLASITFQNYFRMYGKLAGMTGTAATEADEFYDIYKLEVVEIPTNVTIARLDEDDEVYRTQTEKYAAILAEVERANKRLQPVLVGTASIEKSEVLADVLLKSGYKQIDFGDPKALEKLYAAARAGKPAKLFAVLNARFHEQEAYIVAEAGVPGAITIATNMAGRGTDIKLGGSLEMRIQQETADITDEAEKAARIEQIKADIERFRQIVLNAEDEVEIEPAKGNKPAKTAKRPGGLYIIGSERHESRRIDNQLRGRSGRQGDPGRSKFFLSLEDDLMRIFGSGKLDTMLTRLGLKEGEAIIHPWINKALEKAQQKVEARNFDIRKNLLKFDDVQNDQRKVIFDQRIELMKEDSVVETVTDMRHTFIEDLVSKHVPEHAYAEQWDVAGLKEELNRVVGLDIPVDEWAKEEGIADEELLVRLEKVFDEHMAAKVAQWGPDVMRYAEKSILLQTLDHLWREHLVMLDHLRQVIGLRGYGQRDPLQEYKSEAFNLFQEMSAHLREAVTAQLMRVEIIPPEQPRELPPMEVHKMDPNTGEDEMQFANVSLAPADTVEKSERDPNRPESWGKVGRNEDCPCGSGKKYKHCHGRYA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CCR4_DEBHA
Sequence: MNIPKYQQAQVQGQQPNLQAQQILLQQLQQGQSQQSQPSIGGSGSAGQFSQQDIYNDNIAQQGLYQNSYQRPVQAQQPPQLQNIHQQQQFFPQQFSSQQQNQPQASSLQQYQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQIHLPQQYQQSQGQQVPHQPPHIQQQQFFNQQAAALQQQQQQQQQQQQQQQQPAQKLNSINIENPNSIYWQHQQQLCQLSRNANIPHYYARQYAANSRKNKNPYSDVKTVSLIDATRSIVSALNEQENSKSNPGSATNSALLQNKKLAQDLDDDHLQEEQRMRQKTQGRQLWCQLDLSGQGLVNLSPKLFQYDFLESLYLNNNKLTSVPPIVNKLRSLRTLDLSHNRINEVPSELGMCFNLRYLYLFDNNIKTLPNEFGNLIELLFLGIEGNPIDLKIANLVAEKGTKELIAYLRDLKPSFSKPPPRQWLLLEDDGEIIDPINNPDAYTNDNNNSDTNDTFTMMSYNTLCQHYATTKMYKYTPSWALEWGFRRAALQEEVLHFKSDLVCMQEVETRTFHEFWVPVMQGFGYKGVFFNKTRSKTMSESDSKKVDGCATFYKTDKFELLHKQNFEYNSVCMGSDKYKKTKDLFNRFMNKDNIALITYFNHIQTGEKILFVNTHLHWDPAFNDVKTLQVGILLEELRTIMKKYHHTNSIDEIKNASMVICGDFNSTKENAVYQLFSTGAVSNHEDLEGRDYGKFTDEGFRHSFKLKSAYDHVGELPFTTISPAFTDAIDYIWYSTPTLQVKGLLGKIDEEYSSHCIGFPNAHFPSDHIPLVTKFQIKKSGGNKKPDFKPDFKPDFKSGSSRKT
What is the function of this protein?
Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity).  Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity).
What are the official names of this protein?
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4, Carbon catabolite repressor protein 4, Cytoplasmic deadenylase, Glucose-repressible alcohol dehydrogenase transcriptional effector.
What is the protein family that this protein belongs to?
Belongs to the CCR4/nocturin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PAX9_MACMU
Sequence: MEPAFGEVNQLGGVFVNGRPLPNAIRLRIVELAQLGIRPCDISRQLRVSHGCVSKILARYNETGSILPGAIGGSKPRVTTPTVVKHIRTYKQRDPGIFAWEIRDRLLADGVCDKYNVPSVSSISRILRNKIGNLAQQGHYDSYKQHQPTPQPALPYNHIYSYPSPITAAAAKVPTPPGVPAIPGSVAMPRTWPSSHSVTDILGIRSITDQVSDSSPYHSPKVEEWSSLGRNNFPATAPHAVNGLEKGVLEQEAKYGQAPNGLPAVGSFVSASSMAPYPTPAQVSPYMTYSAAPSGYVAGHGWQHAGSTPLSPHNCDIPASLAFKGMQAAREGSHSVTASAL
What is the function of this protein?
Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.
What are the official names of this protein?
Paired box protein Pax-9.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_HAPGR
Sequence: MTNIRKNHPLMKIMNSSFIDLPAPSNISSWWNFGSLLGACLALQIITGLFLAMHYTADTMTAFSSVTHICRDVNYGWVIRYLHANGASMFFLCLFIHIGRGLYYGSFTLSETWNVGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVMVHLLFLHETGSNNPLGTSSDSDKIPFHPYYTIKDLLGLMFLILLTMTLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILAIIPMLHTAKQRSMTFRPLSQSVFWVLTADLFILTWIGGQPVEHPFITIGQMASILYFSLILIIMPMASLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS13_VARPS
Sequence: MARIAGINIPPHKHAEIGLTAIFGIGRTRARQICEASGIEYSKKIKDLTDADLEKIRDQIALFTIEGDLRRETTMNIKRLMDIGCYRGFRHRRGLPMRGQRTRTNARTRKGPRKAAQSLKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ABCF1_PIG
Sequence: MPKGPKQQPPEPEWIGDGESTSPTDKVVKKGKKDKKTKKTFFEELAVEDRQAGEEEKVLKEKEQQQQHQQQQQKKKRDTRKGRRKKDVDDDDGEEKELMERLKKLSVPASDEEEEAPAPVPRGGKKNKGGNVFAALIQDQSEEEEEEEKHPPKPAKPEKNRINKAVSQEQQPGPKGRKGKEEKSKGKAKPQNKFAALDDEEEQDEEEIKEKEPPKQGKEKAKKAEQMEYERQVASLKAANAAENDFSVSQAEMSSRQAMLENASDIKLEKFSISAHGKELFVNADLYIVAGRRYGLVGPNGKGKTTLLKHIANRALSIPPNIDVLLCEQEVVADETPAVQAVLRADTKRLKLLEEERRLQGQLEQGDDTAADRLEKVYEELRATGAAAAEAKARRILAGLGFDPEMQNRPTQKFSGGWRMRVSLARALFMEPTLLMLDEPTNHLDLNAVIWLNNYLQGWRKTLLIVSHDQGFLDDVCTDIIHLDAQRLHYYRGNYMTFKKMYQQKQKELLKQYEKQEKKLKELKAGGKSTKQAEKQTKEALTRKQQKCRRKNQDEESQEAPELLKRPKEYTVRFTFPDPPPLSPPVLGLHGVTFGYEGQKPLFKNLDFGIDMDSRICIVGPNGVGKSTLLLLLTGKLTPTRGEMRKNHRLKIGFFNQQYAEQLRMEETPTEYLQRGFNLPYQDARKCLGRFGLESHAHTIQICKLSGGQKARVVFAELACREPDVLILDEPTNNLDIESIDALGEAINEYKGAVIVVSHDARLITETNCQLWVVEEQSVSQIDGDFDDYKREVLEALGEVMVSRPRE
What is the function of this protein?
Required for efficient Cap- and IRES-mediated mRNA translation initiation.  Not involved in the ribosome biogenesis (By similarity).
What are the official names of this protein?
ATP-binding cassette sub-family F member 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
Protein: AROK_STAAN
Sequence: MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRILRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP8_LODEL
Sequence: MPQSFKELGVAKWLSESLEAMKIHSPTSIQSACIPEILKGRDCIGGAKTGSGKTIAFAALMLTQWSQDPFGIFGLILTPTRELALQIAEQFAALGALMNIKVCVVVGGEDFVKQTLELQKKPHFVIATPGRLADHILNSGEETVSGLRRIKYLVLDEADRLLSNSFGSDLQRCFTILPPSEKRQTLLFTATVTDAVKALKDKPRAEGKLPVFLHQVDAGVDQIAIPKTLSTMYVFVPSYVKEAYLTSILKLPKYEESTAVVFVNRTMTAEVLRRMLRKLEFKVASLHSEMPQTERTNSLHRFKAGAARILIATDVASRGLDIPTVELVVNFDIPADPDDFIHRVGRTARAGRKGDAISIIGEKDIERIESIEERINKKMELLEGVDDDKVINDSLQKATTAKREAMLDMDKESFGERRKVNKKKRAVEEPSGKRQQKKVKKVKS
What is the function of this protein?
ATP-binding RNA helicase involved in 40S ribosomal subunit biogenesis and is required for the normal formation of 18S rRNAs through pre-rRNA processing at A0, A1 and A2 sites.  Required for vegetative growth (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP8.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX49/DBP8 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: COW1_CONAO
Sequence: MGKLTILVLVAAILLSTQVMVQGDRDQPADRNAVPRDVNPGRARRKLMKVLRESECPWKPWCG
What is the function of this protein?
Its target is unknown, but this toxin may modulate voltage-activated calcium channels (Cav) or calcium-dependent potassium channels (KCa).
What are the official names of this protein?
Contryphan-Ar2, Ar1260, Ar1304.
What is the protein family that this protein belongs to?
Belongs to the O2 superfamily. Contryphan family.
What are the subcellular locations of this protein?
Secreted.
Protein: EMTA_ECOK1
Sequence: MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQIKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSDRKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
What is the function of this protein?
Murein-degrading enzyme.  May play a role in recycling of muropeptides during cell elongation and/or cell division.  Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain.
What are the official names of this protein?
Endo-type membrane-bound lytic murein transglycosylase A, Peptidoglycan lytic endotransglycosylase.
What is the protein family that this protein belongs to?
Belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: ORML3_DANRE
Sequence: MNVGTAHSEVNPNTRVMNSRGIWLSYVLGIGLLHIILLSIPFVSVPVVWTLTNLIHNMCMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIILYFLTSFYTKYDRVHFVINTISLLTVLIPKLPQFHGVRLFGINKY
What is the function of this protein?
Negative regulator of sphingolipid synthesis.
What are the official names of this protein?
ORM1-like protein 3.
What is the protein family that this protein belongs to?
Belongs to the ORM family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: KAD_HYDS0
Sequence: MILVLLGPPGSGKGTQGALLKSELSFEHISTGDMLRAEVSKKSPLGLKAEEYMKQGLLVPDDLIIAMIKNILTEAPHKNYVFDGFPRNVNQAEAFETMLNTMRLQVDKVFYFDLEDDVIIKRLSGRRVCPKCGATYNIYYQKPKNDTLCDNDATPLIQRDDDKEEVIVNRLRVYKEQTFPLIEYYKYKNKLFVVSADGTQEEVFEKLKSML
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF3_STRZT
Sequence: MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVKGKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMAVDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILGIASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDDIELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGEIVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNVTQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVSAKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAEVVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDVELEEKM
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_NITOC
Sequence: MARKTPIERYRNIGIMAHIDAGKTTTTERILYYTGVSHKLGEVHDGAATMDWMEQEQERGITITSAATTCFWSGMARQFPEHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFCAVGGVEPQSETVWRQANKYKVPRLAFVNKMDRQGADFLRVVGQIRSRLGANPIPIQIPIGAEENFEGVVDLIKMKAIHWDKSSMGMAFEEKEIPGNLQASCDEYREKMIEAAAEASEELMERYLEEGQLPLDDIVKGLRIRTLNGEIVPALCGSAFKNKGVQAMLDAVLSYMPSPVEVPPIKGVQKDETEGERHASDEEPFAALAFKIASDPYVGNLTFFRVYSGVLSSGDTVYNAASGNRERIGRLLQMHSNSREEIKDVMAGDIAAAVGLKNVTTGDTLCDPNHIILLERMEFPEPVISVAIEPKTKGDQERMSIALGKLAREDPSFRVRTDEESGQTIIAGMGELHLDIIVDRMRREFKVEANVGAPQVAYRETIRRSIEQEGKFVRQSGGRGQYGHVWLKLEPQERGKGYEFVNKIVGGTVPKEFIPAVDKGIKEQTENGVIAGYPVVDIKATLYDGSYHDVDSSEMAFKIAGSMAFKEGVQKANPVLLEPIMKVEVVTPEEYMGDVMGDLNRRRGMVQGMEDSLSGKIIRAEVPLAEMFGYATDLRSATQGRANYTMEFSKYNEAPSNIAGAIIKKSQ
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_SULDN
Sequence: MGMPSGQELLIILAIVVLLFGAKKIPELAKGIGKGIKNFKAEMKNEDDDTEVKSASTEAPKKVESAEEVASKESSKTPTQA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: LEUC_SHIFL
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAALVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: GPDA_STRA5
Sequence: MTKQKIAVLGPGSWGTALAQVLNDNGHEVRLWGNVVEQIEEINTNHTNQRYFKDITLDSKIKAYTNLEEAINNVDSILFVVPTKVTRLVAKQVANLLKHKVVLMHASKGLEPGTHERLSTILEEEISEQYRSDIVVVSGPSHAEEAIVRDITLITAASKDIEAAKYVQKLFSNHYFRLYTNTDVVGVETAGALKNIIAVGAGALHGLGYGDNAKAAIITRGLAEITRLGVQLGADPLTFSGLSGVGDLIVTGTSVHSRNWRAGDALGRGEKLEDIEKNMGMVIEGISTTKVAYEIAQNLNVYMPITEAIYKSIYEGANIKDSILDMMSNEFRSENEWH
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCS22_FRACC
Sequence: MSDARIVAVGVEEEFHILDLTTRQLVPRAEEVLRRLDGDSFSPELLKSVVETNSQPTADLLELRTNLLDLRRRLAEVTGELGLGPAAAGTVPIVDMDLLDVSRDDRYEQMTEDYQIVAREQLICGAQVHVDVADRDLAMAVVAWTAPWLPMLLALSASSPFWMGADSGYASMRTLVWQRWPTAGVAGSFRTAAEYDQLVADLIKSGVISDPGMVYFDVRPSAHLPTVELRICDACPDVDNVILIAGLFRALVCQAIEEIEAGGQAPPPRAELLRAATWRAARSGLEGDLVDILGAGPIPAQAMLRRLLTEVRPQLERFDDWELIDNLAEQAVGRGSSAHRQRRAFARRGLLTDVADLVLAETRDVPPAGAAAALGSAPAVSASDQIAPRLLERYQPTGYDEIVDARGAVRPQYRAVMRTLERLGPGILDERVGTREAEQNDRGIVFRASGDSASRPFPFDLVPRIIAADDWTTLTTGLSQRVRALEAFLHDIYGERAAVADGIVPAWVVNDAPSLRHGGRAVGPDAIRVTVAGIDLVRGGDGGWLVLEDNLRVPSGIAYAMEGRRLAESVLPELGPPAGILRLDGIPALLHEALVAAAPAAATGDPAVAVLTGGKTDAAYFEHSLLAEKMGVALVEPADLLVDDNDVVYRIDGSRRCRVDVLYRRMDEDDLFGALGAAGTPLGLPLLRAIRARRVGIANALGNGVGDDKVVYAYVPRMVTYYLGEQPVLDDVPTYVCGDPEQCEHVLDNLDQLVVKPVDGYGGSGVVIGPHAEPYRLTEVRERILANPRQWIGQELVSLSTHPTWHDSHLEPCAVDLRVFVYAGREPRVVPAALSRVAPPGSLIVNSSQGGGSKDTWIPRR
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2-2, Gamma-glutamylcysteine synthetase 2-2, GCS 2-2, Gamma-GCS 2-2.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.