PharMolix/UniProtQA huggingface dataset:
Protein: E3GL_ADE06
Sequence: MRYMILGLLALAAVCSAAKKVEFKEPACNVTFKSEANECTTLIKCTTEHEKLIIRHKDKIGKYAVYAIWQPGDTNDYNVTVFQGENRKTFMYKFPFYEMCDITMYMSKQYKLWPPQKCLENTGTFCSTALLITALALVCTLLYLKYKSRRSFIDEKKMP
What is the function of this protein?
Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface.  Also delays the expression of class I alleles that it cannot affect by direct retention.  Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes (By similarity).
What are the official names of this protein?
Early E3 18.5 kDa glycoprotein, E3-19K, E3gp 19 kDa, E19, GP19K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae E19 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: DBLOH_HUMAN
Sequence: MAALKSWLSRSVTSFFRYRQCLCVPVVANFKKRCFSELIRPWHKTVTIGFGVTLCAVPIAQKSEPHSLSSEALMRRAVSLVTDSTSTFLSQTTYALIEAITEYTKAVYTLTSLYRQYTSLLGKMNSEEEDEVWQVIIGARAEMTSKHQEYLKLETTWMTAVGLSEMAAEAAYQTGADQASITARNHIQLVKLQVEEVHQLSRKAETKLAEAQIEELRQKTQEEGEERAESEQEAYLRED
What is the function of this protein?
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway.  Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).  Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases.  Isoform 3 attenuates the stability and apoptosis-inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway.  Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation.  Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance.
What are the official names of this protein?
Diablo IAP-binding mitochondrial protein, Diablo homolog, mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase, Smac.
What are the subcellular locations of this protein?
Mitochondrion. Note=Released into the cytosol when cells undergo apoptosis.
Protein: RS3_STAAS
Sequence: MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINVIEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQVSGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: YJZI_SCHPO
Sequence: MTEQNIDIKRELKDESPIGQSPHLENDGRPSLMSRYSYSSIEEVSKEGYQWFKHQSVFLKFSLIVLLFSLMFSLTFGSLLGLISLALGFPSVGYRYVLLPILNALLNRLRLNSSGLK
What are the official names of this protein?
Uncharacterized membrane protein C338.18.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: TALA_ECOLI
Sequence: MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase A.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_MARMS
Sequence: MANSAGSKKRARQAVKSRAHNGSLRSMVRTYLKKVDAAIEAGNQADAQAAYVLATSKLDKAADKGLYHKNKAARHKSRLSAKIKALA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: FAOMT_VITVI
Sequence: MSSSSHRGILKTEALTKYLLETSAYPREHEQLKGLREATVEKHKYWSLMNVPVDEGLFISMLLKIMNAKKTIELGVFTGYSLLATALALPQDGKIIAVDPDKEAYQTGVPFIKKAGVEHKINFIQSDAMSVLNDLIADGKEEGTLDFAMVDADKENYLNYHELLLKLVRVGGIIAYDNTLWFGSVARSEEEEMMDFERAGRVHLMKLNKFLASDPRVELSHLSIGDGVALCRRLY
What is the function of this protein?
Mediates O-methylation of anthocyanins.  Anthocyanins are major pigments in grapes: at ripening initiation in red grapevine berries, the exocarp turns color from green to red and then to purple due to the accumulation and extent of methylation of anthocyanins.  Catalyzes both 3' and 5' O-methylation of anthocyanins, with a preference for glycosylated substrates.  Active on both anthocyanins and flavonols in vitro.  Most active with delphinidin 3-glucoside but also acts on cyanidin 3-glucoside, cyanidin, myricetin, quercetin and quercetin 3-glucoside.  Not able to methylate flavan type skeletons with chiral centers, such as catechins or dihydroquercetin.
What are the official names of this protein?
Flavonoid 3',5'-methyltransferase, Anthocyanin-O-methyltransferase, VvAOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. CCoAMT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_PROMS
Sequence: MSKLFDSRLADVIRKPVITEKATNALDLNQYTFEVDHRAAKPQIKAAVEALFSVKVIGVNTMNPPRRTRRVGKFSGKRSQVKKAIVRLAEGDKIQLFPES
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: HOSC_YEAST
Sequence: MTAAKPNPYAAKPGDYLSNVNNFQLIDSTLREGEQFANAFFDTEKKIEIARALDDFGVDYIELTSPVASEQSRKDCEAICKLGLKAKILTHIRCHMDDAKVAVETGVDGVDVVIGTSKFLRQYSHGKDMNYIAKSAVEVIEFVKSKGIEIRFSSEDSFRSDLVDLLNIYKTVDKIGVNRVGIADTVGCANPRQVYELIRTLKSVVSCDIECHFHNDTGCAIANAYTALEGGARLIDVSVLGIGERNGITPLGGLMARMIVAAPDYVKSKYKLHKIRDIENLVADAVEVNIPFNNPITGFCAFTHKAGIHAKAILANPSTYEILDPHDFGMKRYIHFANRLTGWNAIKARVDQLNLNLTDDQIKEVTAKIKKLGDVRSLNIDDVDSIIKNFHAEVSTPQVLSAKKNKKNDSDVPELATIPAAKRTKPSA
What is the function of this protein?
Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate.  Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.
What are the official names of this protein?
Homocitrate synthase, cytosolic isozyme, HCS.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRAAH_MYCTO
Sequence: MAISFRPTADLVDDIGPDVRSCDLQFRQFGGRSQFAGPISTVRCFQDNALLKSVLSQPSAGGVLVIDGAGSLHTALVGDVIAELARSTGWTGLIVHGAVRDAAALRGIDIGIKALGTNPRKSTKTGAGERDVEITLGGVTFVPGDIAYSDDDGIIVV
What is the function of this protein?
Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate.  Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions (By similarity).
What are the official names of this protein?
Putative 4-hydroxy-4-methyl-2-oxoglutarate aldolase, HMG aldolase, Oxaloacetate decarboxylase, OAA decarboxylase, Regulator of ribonuclease activity homolog, RraA-like protein.
What is the protein family that this protein belongs to?
Belongs to the class II aldolase/RraA-like family.
Protein: KAE1_AERPE
Sequence: MPPKRDGEVLVLGIESTAHTFGVGIVSTRPPIVRADVRRRWTPREGGILPREVAEFFSLHAGEAVAEALGEAGVSIADVDAVAVALGPGMGPALRVGATVARALSAKYGKPLVPVNHAVAHVEAARFTTGLRDPVALYVAGGNTTVVSFVAGRYRTFGETLDIALGNLLDTFAREAGIAPPYVAGGLHAVDRCAEGGGFVEGIPYVVKGQDVSFSGILTAALRLLKRGARLSDVCYTLREVAFSSVVEVTERCLAHTGKRQATLTGGVAANRVLNEKMSLMAGLHGAVYRPVDVRLSGDNGVMIALTGLAAYLHGVIIDPGEAYIRQRWRIDEVDIPWYPWLPGDPPPG
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSIE_YERPE
Sequence: MAKNSRSQWIAKNLQRLLNVGLIMLAAILVVFLVKETIHLGKVLFLSNQETSSYMLIEGIVIYFLYFEFIALIVKYFESGYHFPLRYFIYIGITAIIRLIIVDHENPIDTLIYSGSILVLVVTLYLANTERLKRE
What are the official names of this protein?
Protein PsiE homolog.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NUDI_ECOHS
Sequence: MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSANREVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: RPOZ_ESCF3
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: QUEA_ALISL
Sequence: MQVSDFHFELPDELIARYPQPERTASRLLHLNGNSGELHDGQFTDVLDLVQHGDLVVFNNTRVIPARMFGVKASGGKLEVLVERVLDDHSVLAHVRCSKSPKPGNQLWLGENQEYEAEMVARHDTLFEIRFTSEKKVLDILDEIGHMPLPPYIDRPDEDADKERYQTVYNEKPGAVAAPTAGLHFDTDILEKMKAKGVEFAYVTLHVGAGTFQPVRVDNILDHHMHSEYAEVSQEVVDAIKATKARGGRVISVGTTSVRSLESAAQHALKQGTELAPFFDDTEIFIYPGYEFQVVDALVTNFHLPESTLIMLVSAFAGYDNTMKAYDQAVNHQYRFFSYGDAMFITKKTS
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUTA_YERP3
Sequence: MSDSDAMTDPNAVSYSNAIVVLCTAPDEASAQNLAAQVLGEKLAACVTLLPGATSLYYWEGKLEQEYEVQLLFKSNTDHQQALLTYIKQHHPYQTPELLVLPVRDGDKDYLSWLNASLL
What is the function of this protein?
Involved in resistance toward heavy metals.
What are the official names of this protein?
Divalent-cation tolerance protein CutA.
What is the protein family that this protein belongs to?
Belongs to the CutA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFP_ACIC1
Sequence: MATTNDLKNGMTLDLDGELWNVVEFQHVKPGKGPAFVRTKLKHVLTGKVVDKTFNAGVKVDVATVDKRTMQYLYREGDSFVFMDTETYDQYHIPAQTVGDAANFLLENAEAVVALHEGTPLYVELPAAVELTITYTEPGVQGDRSTGGTKPATLETGAQIQVPLFITTGEKVKVDTRTGEYLGRANS
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPDA_RHOPS
Sequence: MSAFNSISVLGGGAWGTALALTAARAGRSVTLWEHDPGHAQHLEQTRESRFLPGVMLEPSIKVTRDLAEAARAEALLLVVPAQVLRSVATSLQPLIAARTPLIACAKGIEHGTHRFMTEIIAECAPNAIPAILSGPSFAADVARGLPTAVTIAASDAAIAQALAQAMNSGSFRPYHSTDVRGVELGGATKNVMAIAAGIVAGRKLGASALAAMTTRGFVELVRFGKAYGARIETMHGLSGLGDLTMCCSTPQSRNFSFGMALGRGESIDEAAHGKLAEGYYTAPVLLEMAQAKGVEMPISTAVAAILQGQLGVDAAIEGLLTRPLKAEE
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RN139_PONAB
Sequence: MAAVGPPQQQVRMAHRQVWAALEVALRVPCLYIIDAIFNSYPDSSQSRFCIVLQIFLRLLGIFVSSIVLILSQRSLFKFYMYSSAFLLAATSVLVNYYASLHIDFYGAYNTSAFGIELLPRKGPSLWMALIVLQLTFGIGYVTLLQIHSIYSQLIILDLLVPVIGLITELPLHIRETLVFTSSLILTLNTVLVLAVKLKWFYYSTRYVYLLVRHMYRIYGLQLLMEDTWKRIRFPDILRVFWLTRVTAQATVLMYILRMANETDSFFISWDDFWDLICNLIISGCDSTLTVLGMSAVISSVAHYLGLGILAFIGSTEEDDRRLGFVAPVLFFILALQTGLSGLRPEERLIRLSRNMCLLLTAVLHFIHGMTDPVLMSLSASHVSSFRRHFPVLFVSACLFILPVLLSYVLWHHYALNTWLFAATAFCVELCLKVIVSLTVYTLFMIDGYYNVLWEKLDNYVYYVRSTGSIIVFIFGVVMFGNGAYTMMFESGSKIRAFMMCLHAYFNIYLQAKNGWKTFMNRRTAVKKINSLPEIKGSRLQEINDVCAICYHEFTTSARITPCNHYFHALCLRKWLYIQDTCPMCHQKVYIEDDIKDNSNVSNNNGFTPPNETPEEAVREAAAESDRELNEDDSTDCDDDVQRERNGVIQHTGAAAEEFNDDTD
What is the function of this protein?
E3-ubiquitin ligase; acts as a negative regulator of cell proliferation through mechanisms involving G2/M arrest and cell death.  Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER).  Affects SREBP processing by hindering the SREBP-SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression.  Involved in the sterol-accelerated degradation of HMGCR.  This is achieved through binding to INSIG1 and/or INSIG2 at the ER membrane.  In addition, interaction of RNF139 with AUP1 facilitates interaction of RNF139 with ubiquitin-conjugating enzyme UBE2G2 and ubiquitin ligase AMFR, leading to ubiquitination of HMGCR.  The ubiquitinated HMGCR is then released from the ER by the complex into the cytosol for subsequent destruction.  Required for INSIG1 ubiquitination.  May be required for EIF3 complex ubiquitination.
What are the official names of this protein?
E3 ubiquitin-protein ligase RNF139, RING finger protein 139, RING-type E3 ubiquitin transferase RNF139, Translocation in renal carcinoma on chromosome 8 protein.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LEUC_CALS8
Sequence: MSKPMTMSQKILAYHAGKEYVEPGDLIFANVDLVLGNDVTTPVAIKEFEKIGVDKVFDKDKITIVPDHFTPNKDIKSAQQCKMVREFAKKYDITNYFEVGEMGIEHALLPEKGLVVPGDLVIGADSHTCTYGALGAFSTGIGSTDMACAMATGKCWFKVPEAIKFVLYGKKTGWTSGKDIILHIIGMIGVDGALYKSMEYTGEGLKSLSMDDRFTIANMAIEAGAKNGIFEVDEKTIEYVKQHSTKPYKIFKADEDAEYSEVYEIDISKIRPTVAFPHLPENTKTIDEITEKIYIDQVVIGSCTNGRIEDLRIAAKILKGRKVKKGLRCIIFPATQNIYKQALKEGLIEIFIDAGCVVSTPTCGPCLGGHMGILAEGERALATTNRNFVGRMGHPNSEVYLSSPAIAAASAVLGYIGSPEELGMKGDEE
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: PER70_MAIZE
Sequence: MASSSFTSLSVMVLLCLAAAAVASAQLSPTFYSRSCPRALATIKAAVTAAVAQEARMGASLLRLHFHDCFVQGCDGSVLLNDTATFTGEQTANPNVGSIRGFGVVDNIKAQVEAVCPGVVSCADILAVAARDSVVALGGPSWRVLLGRRDSTTASLALANSDLPAPSLDLANLTAAFAKKRLSRTDLVALSGAHTIGLAQCKNFRAHIYNDTNVNAAFATLRRANCPAAAGNGDGNLAPLDTATPTAFDNAYYTNLLAQRGLLHSDQQLFNGGATDGLVRTYASTPRRFSRDFAAAMIRMGNISPLTGTQGQIRRACSRVN
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 70, Plasma membrane-bound peroxidase 2b, pmPOX2b.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MUTL_ECO45
Sequence: MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASISSVSRLTLTSRTAEQQEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKFLRTEKTEFNHIDEIIRRIALARFDVTISLSHNGKIVRQYRAVPEGGQKERRLGAICGTAFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQACEDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQLETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAVREPVAPRYSPAPASGSRPAASWPNAQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLERDGNISLLSLPVAERWLRQAQLTPGEVPVCAQPLLIPLRLKVSGEEKSALEKAQSALAELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLMSEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: MOBA_METTH
Sequence: MSELDSVAVLCGGRGRRMGSDKGLLLMDDRPFIEIITAKLLGHFSDVLVVLRDTDQAGTYRGILDDRVRILTDELPGAGPLGGIYTALGNISGDAALFLPCDAPLVTDEFLVNMKECFRRLGDSCDAIVPWGDDGPEPLHAVYSARVRGTVEALLSKNKRRVGTLIESINSCRIAAIRLDPTLQSFRNFNRPEDLRI
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABG_STAAS
Sequence: MKMTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKAKYITGQTIHVNGGMYM
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
What are the official names of this protein?
3-oxoacyl-[acyl-carrier-protein] reductase FabG, 3-ketoacyl-acyl carrier protein reductase, Beta-Ketoacyl-acyl carrier protein reductase, Beta-ketoacyl-ACP reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: LR74A_RAT
Sequence: MDDDDIEPLEYETKDETEAALAPQSSEDTLYCEAEAAPSVEKEKPTREDSETDLEIEDTEKFFSIGQKELYLEACKLVGVVPVSYFIRNMEESCMNLNHHGLGPMGIKAIAITLVSNTTVLKLELEDNSIQEEGILSLMEMLHENYYLQELNVSDNNLGLEGARIISDFLQENNSSLWKLKLSGNKFKEECALLLCQALSSNYRIRSLNLSHNEFSDTAGEYLGQMLALNVGLQSLNLSWNHFNVRGAVALCNGLRTNVTLKKLDVSMNGFGNDGALALGDTLKLNSCLVYVDVSRNGITNEGASRISKGLENNECLQVLKLFLNPVSLEGAYSLILAIKRNPKSRMEDLDISNVLVSEQFVKVLDGVCAIHPQLDVVYKGLQGLSTKKTVSLETNPIKLIQNYTDQNKISVVEFFKSLNPSGLMTMPVGDFRKAIIQQTNIPINRYQARELIKKLEEKNGMVNFSGFKSLKVTAAGQL
What are the official names of this protein?
Leucine-rich repeat-containing protein 74A, Leucine-rich repeat-containing protein 74.
Protein: GSA_SOYBN
Sequence: MAVSAITGARLTLGMSLSSSTRSRTVAMAVSIDPKTDNKLTLTKSEEAFAAAKELMPGGVNSPVRAFKSVGGQPIVIDSVKGSRMWDIDGNEYIDYVGSWGPAIIGHADDQVLAALGETMKKGTSFGAPCLLENTLAELVIDAVPSIEMVRFVNSGTEACMGALRLARAYTGREKIIKFEGCYHGHADPFLVKAGSGVATLGLPDSPGVPKAATFETLTAPYNDTEAIEKLFEANKGEIAAVFLEPVVGNAGFIVPKPDFHSFLRKITKENNTLLVFDEVMTGFRLSYGGAQEYFGITPDITTLGKIIGGGLPVGAYGGRRDIMEKVAPAGPMYQAGTLSGNPLAMTAGIETLQRIKEPGTYEYLDKITGELVEGIIEAGKRAGHAICGGHIRGMFGFFFTEGPVYNFADAKKSDTAKFARFFWGMLAEGVYLAPSQFEAGFTSLAHTSDDIKKTIAAAEKVFREI
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CENPU_CHICK
Sequence: MSSKKRTKRNRAGDEYKEHKGRSHPRRKFLPPEEPDVSRISKVAGVNQLEELCDSFDQPLHSTAVDACGEEHSENESSGYVPAPQRTNAERSEKMLLETPEGDVHEFSQSGSVREPLMENLNAPNTTRSEVKKKRPSKKSSSDSSVNSPSSVQLWCPNKLKRSSRDITELDVVLAEFEKIAANYRQSIESKACRKAVSAFCSAFEDQVTDLITEVQELKNTKKKNAKVVADIKKKRQRLMQVREKLSRTEPQLIKLQKEYAEVEERRSSLRQVVQFLTDLKELQQDYLDYREENPRKKVVYGASSLPALLVESRRILQAERHFQNINRKLEYALEVQRGKLAKEH
What is the function of this protein?
Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.  Required for maintenance of sister chromatid adhesion during mitotic checkpoint activation.
What are the official names of this protein?
Centromere protein U, CENP-U, Centromere protein p50, MLF1-interacting protein, centromere protein of 50 kDa, CENP-50.
What is the protein family that this protein belongs to?
Belongs to the CENP-U/AME1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes to the centromeres throughout the cell cycle.
Protein: KDSA_KLEP7
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEASQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFIEGGNDKVILCDRGANFGYDNLVVDMLGFGVMKKASNNSPVIFDVTHALQCRDPFGAASGGRRAQVSELARAGMAVGIAGLFIEAHPDPDHAKCDGPSALPLDKLEPFLKQMKAIDDLVKSFDELDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.