PharMolix/UniProtQA huggingface dataset:
Protein: CSRA1_COXBU
Sequence: MLVLTRTNGQAIKIGNEGEITVTVLEVRGNQVRMGIDAPKHIAVHREEIYQRIQEEKPKAPPILEEVE
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA 1, Carbon storage regulator 1.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DOSC_SHIFL
Sequence: MEMYFKRMKDEWTGLVEQADPLIRAKAAEIALAHAHYLSIEFYRIVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIGIPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDSSASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKVLLDSDLGSSLPLSQADFGLWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRILNNRSLRVKFLLQIRNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDVDKFKEINDTWGHNTGDEILRKVSFLSQKRLVKSKILGAGSSRKLAVS
What is the function of this protein?
Globin-coupled heme-based oxygen sensor protein displaying diguanylate cyclase (DGC) activity in response to oxygen availability.  Thus, catalyzes the synthesis of cyclic diguanylate (c-di-GMP) via the condensation of 2 GTP molecules.  Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria (By similarity).
What are the official names of this protein?
Diguanylate cyclase DosC, DGC, Direct oxygen-sensing cyclase.
Protein: MTC6_LODEL
Sequence: MFNLIKIFFLVSLLSKWVFCDESNNSNYNTNTSNTTSNTTSSSISASTINITESINTDVINVAVRTQRDVSKPIPIDQVGVAGISLNSVFDNQGYTADSLAELTNLLQLGTQVVLLTLYWNEFTSVWQLCPAPFPQNVTYYLNSLVNVTWNNNTYLCEYGFTTNDIMDTIFEYLQSSNTVFNVYFMHLLLNLKSIHYEKSNKTIDLENIYAPNSRTNIIGNTTLYDTVAPLSPYIFTPDVLESYQNSEANSTQSNYQQFYAQSNYTFPSLDSVLFLEVKRLLVNVVNNDLVDSRRVYSITLRDRSNIFFNNTMPSTTLDTAEADAFCDRVLNSANDIETFNNLSLYTHFRYVTDNNKKRFTMKGVRRYVKCGLSPVFNASSYQVTNDSFAQTSNQSYYPTANESLLDVEVAFEAFIPYNFWSFAPGQPIMNETTRGNVLSSDANVAYKCVAMNPDGWTVEDCYTEYQYACKNITSPNDWFISTRSRRSYFDIDNDACPDGYNFSLPRLSIEMAALYNVIKKENAEYPVWIDLNDITISTCFVSGGPYAQCPYQKTVTTKKFIRMIAPSSIVALVILFLIFLENLFRKNQLQTNRKKYWKKVLSEHYAKHEQEGVPS
What is the function of this protein?
May be involved in telomere capping.
What are the official names of this protein?
Maintenance of telomere capping protein 6.
What is the protein family that this protein belongs to?
Belongs to the MTC6 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: OST48_PONAB
Sequence: MEPSTAARAWALFWLLPPLLGAVCASGPRTLVLLDNLNVRETHSLFFRSLKDRGFELTFKTADDPSLSLIKYGEFLYDNLIIFSPSVEDFGGNINVETISAFIDGGGSVLVAASSDIGDPLRELGSECGIEFDEEKTAVIDHHNYDISDLGQHTLIVADTENLLKAPTIVGKSSLNPILFRGVGMVADPDNPLVLDILTGSSTSYSFFPDKPITQYPHAVGKNTLLIAGLQARNNARVIFSGSLDFFSDSFFNSAVQKAAPGSQRYSQTGNYELAVALSRWVFKEEGVLRVGPVSHHRVGETAPPNAYTVTDLVEYSIVIQQLSNGKWVPFDGDDIQLEFVRIDPFVRTFLKKKGGKYSVQFKLPDVYGVFQFKVDYNRLGYTHLYSSTQVSVRPLQHTQYERFIPSAYPYYASAFSMMLGLFIFSIVFLHMKEKEKSD
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).  Required for the assembly of both SST3A- and SS3B-containing OST complexes (By similarity).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, DDOST 48 kDa subunit, Oligosaccharyl transferase 48 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the DDOST 48 kDa subunit family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: Y1282_RICCN
Sequence: MLIMKKLLLIAATSATMLSSSVSFAEGMDHEWYLRIDTGAAMFNEEKDKATGVKLKSNTTVPVALGIGYYISENFRADLTLGTIIGGKLKKSGAATNAPFTRTNISASHKPTITRLLINGYVDLTNFDMFDVFAGAGVGSALVKEKITYNGITGLSSNTKNRTNISYKLTLGTSAQIADGVKVELAYSWIDDGRTKSKNVIYQGTSVPTGGMHYQSHNLTAGIRFDI
What are the official names of this protein?
Uncharacterized protein RC1282.
What is the protein family that this protein belongs to?
To R.conorii RC1281.
Protein: TAL_HAEIE
Sequence: MTTQLDSLRNMTVVVADTGDIDAIKKYQPQDATTNPSLILSASALPQYAPLIDEAVAYAKAQSNDKAQQLIDAEDKLAVNIGLEILKIVPGRISTEVDARLSYDTQATVEKARKLIALYNAAGISNDRILIKIASTWQGIRAAEILEKEGINCNLTLLFSEAQARACAEAGVYLISPFVGRILDWYKANSDKKEYAPAEDPGVISVTKIYNYYKEYGYNTVVMGASFRNVGEITELAGCDRLTIAPALLKELQENSTALVRKLEYKGEVKAKPQPLTEAEFYWQHNSDAMAVEKLAEGIRKFAIDQEKLETMLSAEL
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_LACP3
Sequence: MQCPHCHHNSSRVVDSRPTDGGRAIRRRRECENCGFRFTTFERVEQTPLLVIKKNGTREEFNREKILKGLIRAAEKRPVTMEQMQSIVDSVENQLRAIGENEVSSQAIGEFVMSKLADVDDVAYIRFASVYRQFKDMSVFMQELQDMMKKEKTKK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: YD537_YEAST
Sequence: MFSRWMEDKGVSRVTSSNLRFSLIETSAALVIKSSVKPILIAASDFMEQGTTIIPSCWKDPDEMHAETSRTEYVLVAKAATSCGSQSVSYFIVAAPHFEITKWVSTLNSFSTCRSLIPSATPVAPVIATTILFGLGGEVDALVTSFDSLCVRKDGEVVMVLPSKGKLAKMPVVLKKAILVLLGNRSISTQLKLLNALDSVD
What are the official names of this protein?
Putative uncharacterized protein YDR537C.
Protein: US14_HCMVA
Sequence: METVSTQRETASSETERTREAASAETTDATFRSLEEGSTISSRYSETASTVSEDAVCWLRRTAIVMRVYGLLTLETAFSVLISALVWLGYPSLGYKCSDDPSPLLLSCTPVLVLGALELTDHRHPSNGLVFALYVALLSFTTAGLNLCATAPIGISSLILTWTLFVACNGVAWEHRLSSVWRDALFTSTLLTVMVSVLASTYTWLHKTLLCLYTVFVGCILAVLFQDVRYIATKMPVSHVIRSSLILYATETLIYHTTLLMLTPVVWSARWDQMFSYLAKLGTYHHYLIDNGTLSVILNTTTATFQSKAA
What are the official names of this protein?
Uncharacterized protein HVLF4.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US12 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: ISPE_PSEA7
Sequence: MAVRLSLPAPAKLNLFLHILGRRADGYHELQTLFQFLDHGDELHFETREDGQVRLHTEIAGVPHDGNLIVRAARVLQEASGSTQGVDIWLDKRLPMGGGIGGGSSDAATTLLALNHLWNLGWDEDRIAALGLRLGADVPVFTRGRAAFAEGVGEKLTPVDIPEPWYLVVVPQVLVSTAEIFSDPLLTRDSPAIKVRTVLEGDSRNDCQPVVERRYPEVRNALILLNKFVSARLTGTGGCVFGSFPNKAEADKVSALLPDHLQRFVAKGSNVSMLHRKLETLV
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: TOP2_IIV6
Sequence: MATSNHKKQYTTLSDIDHVLLRPEVIIGSTVPMEQTEYVVDENFSEILEKQVFVSEALIRIFVEVLANAVDNIHRSKGSSTPCKSIKIKIEDDGTTMIHNDGQVIKISKEENDGIEINGKKCSVYNHELVFGHLRSSSNYDDTVVRQTSGKNGLGVKCTNILSKSFKVIGVDPENKKKFVQEWTNNMKETSGPKVTTSSSKTGYTEVIYCPDFERLGNFSSDIIGIFRKHVLDVAMLASSEGVSVYFNDKKLPIKKFSDYTKLFKLEKESISITEEDGSSEVTIAFVERDGKKKPISFVNGLFTKHGGQHVDGWTKPFFANLLSVLNKPSKTYKDLKLSLKDVTPYFRFFVKSTVDKPQFDCQNKNMLKSPCLKYTIPDKIITKVCKWTSVQELKQSSFEKLLKGKDNNIIKTLNDKKRRPKVSVKEYDPANKAGTTLSEKCTLIVCEGLSAKTYAVAGISTGISFTGTDTKKGRDWFGILPLRGKFLNVRNANNDKMIKNTVVTDLVNAMGLTFGMDYSTQKSRKSLNYGSIIIIPDPDEDGIHIEGLVLNFFHHHFSSLFNPVVPNLKDFPFISSMKIPIIKVIEKPLKGRREIEFFTHEAFHKFKNENKWHKNHEIKYFKGLGTTKHEDVPKIFGKKMVVFNIDDNAHENMEKAFKDEEADERKEWLKQYNPNARTFDLDSPNKILQLNISTFINEELIKFSIEDCKRSLPHLIDGLKESQRKVIFGLKQWNGKNNIKVAQLGAFVAQKTDYKHGEQNLFDTIIKMAQTFVGANNIPLLEEDGQFGTRLSGGKDAASPRYIFVNQPPILNKIFRPEDDPILNYTLDGEPVFYAPVIPLICINGSVGVGTGFSCNIPMFNPSEIIDGLKQWINMREQGEKYVFKYKPWYKGFTGKIEKNGSGRYISYGTLSNEASNNGMYQYTVSELPINMWTDKFKEMCDQYRESNLIKTCDNYSEVTTVNFKISSEHELTIENLKLRSYIHTSNMVMFDHEGKIHKYETLNGIMQRFCKERIKIYEKRRQYMLQKLNKSLTISENKKRFMEDVMNQKIKILLQEDEVVHQQLLDMNYYKDDEGEFDYLLNMNIGGFRKKNVDKLISKIDDLKKDIMWYTNTNEGQMWLKDILELEPFI
What is the function of this protein?
Can introduce negative superhelical turns into double-stranded circular DNA.
What are the official names of this protein?
DNA topoisomerase 2, DNA topoisomerase II.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
Protein: COXX_GEOSL
Sequence: MTRQDLVLFRPRLALLNGIAAVAGHALVPDAAHATLWVALAGVAILAAGGSALNQVLERDLDRLMERTRQRPLPRGDLSPAMATALGCACIGTGLLVLAAGGPVPPLLGAVALAWYLAVYTPLKRRTSLALAIGAVSGALPPVIGWTLAGGAPGDYRIILLAGIFFLWQVPHFWLFQRRHADDYRRAGIPLFTPGAGRLGPSFHVRLWLGALAASVLLLPAFGLMAPRMAPWIAAVPLLLLPVCRPRSEATLFSCLNAFPPLMALALLLR
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPQY_MYCT3
Sequence: MDGRQVVRARRWCATAAVALMTASTVAACGSDSGEIVISYYTPANEAATFTAVAQRCNAELGGRFRIEQRSLPREADAQRLQLARRLTGNDRSLDVMALDVVWTAEFAEAGWALPLSEDPAGLAEADATTNTLPGPLETAKWNGELYAAPITTNTQLLWYRADLMDEPPATWDEMLSEAARLHAQGGPSWIAVQGKQYEGLVVWFNTLLESAGGQVLSDDGQRVTLTDTPEHRAATVKALEIIKAVATAPGADPSITQTDENTARLALEQGRAALEVNWPYVLPSLLENAIKGGVGFLPLNENPALRGSINDVGTFAPTDEQFDLALNASKEVFGFARYPGVRPDEPARVTLGGLNLAVASTTRHKAEAFEAVRCLRNEENQRLTSIEGGLPAVRTSLYDDPQFQAKYPQYEIIRDQLINAAVRPATPVYQAMSTRMSATLAPISQIDPERTADELAEQVQQAIDGKGLIP
What is the function of this protein?
Part of the ABC transporter complex LpqY-SugA-SugB-SugC, which is highly specific for uptake of trehalose.  Involved in the recycling of extracellular trehalose released from trehalose-containing molecules synthesized by M. thermoresistibile.  Trehalose uptake is essential for virulence (By similarity).  Binds deuterated trehalose with similar high affinity to trehalose, trehalose analogs including galactotrehalose, 4-azido-4-deoxy-trehalose, 6-azido-6-deoxy-trehalose, 3-azido-3-deoxy-trehalose and mannotrehalose in the order of decreasing affinity, respectively, and 2-azido-2-deoxy-trehalose and kojibiose (alpha1,2-glycosidic bond) with very low affinity.  Does not recognize single glucose, 6-amino-6-deoxy-trehalose, trehalose-6-phosphate, nigerose (alpha1,3-glycosidic bond), maltose (alpha1,4-glycosidic bond), isomaltose (alpha1,6-glycosidic bond) or glycerophosphocholine.  Decreased recognition of alpha,beta-trehalose and almost no recognition of beta,beta-trehalose.  Substrate specificity indicates a strict requirement for an alpha1,1-linked disaccharide (PubMed:33476646).
What are the official names of this protein?
Trehalose-binding lipoprotein LpqY, Extracellular solute-binding protein, SugABC transporter substrate-binding protein LpqY, SugABC transporter SBP LpqY.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
Protein: RTC1_CANTT
Sequence: MSSSTNGHSQSNFAKFAFNIYGTLSTTSSSTPQSHEISPSPSSSLSSSRSRRNKQSFRAATGHRLTYQCDKETISLSQLNYPLQVGGYGTELHSIVIGGKNYLRLLCISESQQRIIDDINLLESKSIYNSRVGSKLININTIKTYESTIATGLSNGVVSVYKISPNGQGKQTGRFSDHKRTINSLDFIESENQLLSGSQDGTIKLWDLRSSSSKPSITIQASMRSDPIRACQYSPHSSVKNKMCVLSVHDSGALCKFDLRSTGGNGNIYSPEKKWNLHTGPALSLHIHPEKEYVITGGRDQRISVFNYGEGQSNSSTPENTIITYGPVLKVRWSSYSNISQSGDEFEEAQSSLSPSKINPLYNYDIACSYLNDDPTVAIYNLSRKYVPKQIIHSKKPIQNFIWARNGHRDRNIWTLTKSNTFNSYNLDQIDEYDVSRPLDDLNNVAVAWDNNGNFSMANQDKYDFELDDNDIYDRPEGSSEAEVASHGMDPEESGNAIHFHNSATTSPVEKAALARSYTHNPMSAIQLPTKSPLPIGRNGTGFLGHDMSLPNISTRPKLTRNTSQTTQDSSVSYGSAYPIPQSANSNTTLHMKRNIISNSTKSSNTSAYVIPVVLPIVSNDEFVFKKLSSEYLVKLPDGFTMIDVCLLNASTAASVNSNRTCQVWRLLAVSLQEHFDSQKAPMTIEELEKQQMEQNENEEGVPNATVESATDSMPAKSVSSVLGNFVESYKTNSSFGTGSQINKPGKSVKSRTSSGVNLMDKINLASRTSSFSKTSFKFKEKEGVDEDGVPEDKEKQERGKAEDQETENDKKSIHSNQEPIVIRTTRHSKVEDLDDENLNIANSMAMKSSPTSVGISLPSSHTFSSSIASSPQPIRGQIPPKQQLATTRESPVHNWLDQKKNELFRGRNVVPAISGLSLALKSSNNGDEKLLTRAWKFKNLLRKSLDYAMLQGDVIFCSTAAILFYEFAEDTISEYEYLEWVSLYIDILQKKKLFVTAINILNSTAGSIKSKLQKIYSVDLDLRFYCSNCETLLVNEKSQMSQKGEFGYWYCDECNKLQSKCVYCNEPCKGLAVVVGLKCGHQGHFGCLKEWFIQDENMECPGGCDYQIL
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat RTC1 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: VAPB_RAT
Sequence: MAKVEQVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGVIDAGASLNVSVMLQPFDYDPNEKSKHKFMVQSMFAPPDTSDMEAVWKEAKPEDLMDSKLRCVFELPAENAKPHDVEINKIMPTSASKTEAPVAAKPLTSPLDDAEVKKVMEECRRLQGEVQRLREESRQLKEEDGLRARKALPSNSPMAALAASGKEEGLSARLLALVVLFFIVGVIIGKIAL
What is the function of this protein?
Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity.  Involved in cellular calcium homeostasis regulation.
What are the official names of this protein?
Vesicle-associated membrane protein-associated protein B, VAMP-B, VAMP-associated protein B, VAP-B.
What is the protein family that this protein belongs to?
Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Protein: TNMD_MOUSE
Sequence: MAKNPPENCEGCHILNAEALKSKKICKSLKICGLVFGILALTLIVLFWGSKHFWPEVSKKTYDMEHTFYSNGEKKKIYMEIDPITRTEIFRSGNGTDETLEVHDFKNGYTGIYFVGLQKCFIKTQIKVIPEFSEPEEEIDENEEITTTFFEQSVIWVPAEKPIENRDFLKNSKILEICDNVTMYWINPTLIAVSELQDFEEDGEDLHFPTSEKKGIDQNEQWVVPQVKVEKTRHTRQASEEDLPINDYTENGIEFDPMLDERGYCCIYCRRGNRYCRRVCEPLLGYYPYPYCYQGGRVICRVIMPCNWWVARMLGRV
What is the function of this protein?
May be an angiogenesis inhibitor.
What are the official names of this protein?
Tenomodulin, TeM, mTeM, Chondromodulin-1-like protein, ChM1L, mChM1L, Chondromodulin-I-like protein, Myodulin, Tendin.
What is the protein family that this protein belongs to?
Belongs to the chondromodulin-1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein. Nucleus envelope.
Protein: PLSY_STRZT
Sequence: MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNTFRILGKKAGMATFVIDFFKGTLATLLPIMFHLQGVSPLIFGLLAVIGHTFPIFAGFKGGKAVATSAGVVFGFAPVFCLYLAVVFFGTLYLGSMISLSSVTASIAAVIGVLLFPLFGFILNNYDPLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DHAS_BUCAP
Sequence: MTKSVGIIGWRGMVGSVLLKRMQEENDFSKIIPYFFSTSQSGQDGPIINNILSKNLKDAYNINLLQEMDIIITCQGSSYTEKIYPKLRNNNWQGYWIDAASTLRMEKDATIILDPVNLNVINNALDKGIKTFVGGNCTVSLMLMALGGLFVNNLIDWVFVSTYQAASGAGSRYVIELLKQMGSLYNVVSKDLLDKSYSVLDIEKKVTQESRSKNFPLENFSVPLATSLIPWIDVEMKNGQSREEWKGQAETNKILNLKKKVLIDGTCVRISSIRCHSQSFLIKLNKDISLENIKKIIVNHNQWVDVIPNNMQKTLCNLTPSAVTDTLNIPIGRLRKLNIDDRYLSAFTVGDQLLWGAAEPLRRMLNLLVNI
What is the function of this protein?
Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
What are the official names of this protein?
Aspartate-semialdehyde dehydrogenase, ASA dehydrogenase, ASADH, Aspartate-beta-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aspartate-semialdehyde dehydrogenase family.
Protein: HEM3_STAS1
Sequence: MRKLVVGSRRSKLALTQSRQFIDKLKAIDPSLEIEIKEIVTKGDLIVDKQLSKVGGKGLFVKEIQNELFNHGIDMAIHSLKDVPSVIPDGLTLGCIPDRENPYDAYIAKNHVPLNELPDNSIVGTSSLRRGAQILAKYPKLQIKWIRGNIDTRLNKLETEDYDAIILAAAGLKRMGWSDDIVTSYLDKETLIPAIGQGALGIECRSDDETLLSLLSKVHNQDVADCVTAERTFLTRMNGSCQVPIGGYATKEADGTIEFTGLIMSPDGKERYQHTVRGTDPVALGEEVTKVLNEQGAYEIIKALNEEQ
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
Protein: SYK_XANC8
Sequence: MTEQTPTPQLPADENSLIAERRAKLGALRGQGIAYPNDFVRTHFAGDLQAEFAEAETWTAEALEAADRSVKLAGRLMAKRVMGKASFAQIQDESGRVQLFLQGNVLGDAYTAFKGWDVGDIVAVEGGLTRTKTGELSVKATALRLLTKSLRPLPDKWHGLSDVEQRYRQRYVDLIVTPEAREVFIKRSKIIRAIRAWLDARRFLEVETPMMHYIPGGATAKPFTTHHNALDLDLYLRVAPELYLKRLVVGGLERVYEINRNFRNEGVSTRHNPEFTMLELYEAYATYHEIMDLTEQVIRDTAQGVLGTTQVSWDGADIDLAPAFRRWRMDEAVRHHNPEISAADCTDRAALLRHCERLKIKVKPSYGWGKLLLEIFESTVEHTLVQPTFITDHPVEVSPLARASDTEPGYTDRFELFINGKELANGFSELNDPEDQAARFQAQVQAKDGGDDEAMHYDADYIRALEYGMAPTGGLGIGIDRLVMLLTGSTSIRDVLLFPYMRPEA
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RON4_TOXGO
Sequence: MAIKNTLTGSGLLVLLTLACGTTVQSSPPTPAPRMYPNMNERPLSAESRLTPGTYRSELHIDLKSPQKTASQSSLAPTGDNNSKVESIIAGSDTTPRSAEGTSESPPVPQLGTPPRPAPRRSKGEGERQPPTAAPRTSRSVDTGSGSDASTEQQAGGQKVVTPIPASKGIYPSLDELRRSQESNVDAGSGTSTNEGGGTSEGPQVPQSGIPPRTGRRRAKARNRKRHPTPASRESSSEDENQPPTTASRPSNGEGESQPPTAAPRTSRSVDTGSGSDASTEQQAGGQKVVTPIPASKGIYPNLDELRQTQEGEESAPQPADVTWFSMSVPMGVVDRRVSRALKEQFFQFLQHLSADYPKQVQTVYEFLGWVADKLPENEEEVQMFIDALNTTEAMVGKAARWIFKAIPERERETIYSSFYQMFRDKLPKKFFETAEGMNPDVGQYFSAEEPVAVTPEIPAKSEEDSEAAETPTPLRRQANVAAQVLHPLPAKGVTRREWIPWPKMQNAISKAHGPLTRVPEWTPVTGSCALGDGYTDIDVTKATTDVLFRITLLILQQIRRKKTERGKLEDDQALVALCSAAGAFVDAWQHQQQALILEDPGTPKAHAQLIERLRNAGKYFMKSYDETTGESDHQQWKKNKAEVSKLGKSALMKSCVKYIKASGDVATRPFDSGTAKYPSRSLYGGIANTLETPFADSEAVAKAVHDYAKEHKKPEKLVGLCGALQISGYFKKCFSDAGRLSSVSFFHQHVDGASVLVRTLARERPIGRHALSQAICDPNISAQYFEGAFRLFSSTVSQEWEKENLFAQLASWTGKEMVLAPSLEEQAAVPPAQPAYETVYGDEEDRIYRIHVSGRHSSPQEVLYVGGIPSTVKPQQVHVLGPTVSDESRRMIHPVRHRSRTAPSSEAASTAAESSDEDPLPAENATAFLGVTPQEEESDAYKHTLDFDAVSPRKNKNKENRISAPLKQSDTLIEESTSKTSEL
What are the official names of this protein?
Rhoptry neck protein 4, Tg65.
What are the subcellular locations of this protein?
Secreted. Parasitophorous vacuole membrane. Note=Located prominently at the junction of the body and neck portion of the rhoptry organelle in tachyzoites and bradyzoites. Upon infection, associates with the parasitophorous vacuolar membrane (PVM).
Protein: TM45B_RAT
Sequence: MANFKGHALPGSFFLIFGLWWSVKYPLKYFHQKGLKKNRLSLQQQRIEIIEGAVKALFAVIGILAEQFVPDGPHLHLYHENQWTKLMNWQHSTMYLFFGVSGIIDMLTYLYFNIVPLGLDRVVLAMAVFVEGFLFYFHVHGRPPLDQHIHSLLLFSLFGATISICLEVILRDNIVLELFRTTLLILQGTWFWQIGFVLFPPFGTPEWDQKDMDNVMFITMCFCWHYLVALCITAINYSLVYCFLTRVRRRAEGEIIGIQKLKSDHTYQSTLLSGSDEE
What is the function of this protein?
Plays a role in innate immunity.
What are the official names of this protein?
Transmembrane protein 45B.
What is the protein family that this protein belongs to?
Belongs to the TMEM45 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: HUTI_SHEPW
Sequence: MSWDQVWIDINIATMSPNISEPYGAIRDAALAVKDGKIAWIGKRCDLPEFDVLATPIYKGKNGWLTPGLIDAHTHLVFAGNRANEFELRLQGASYEEIARNGGGIISTVNACREADEAELFELGRQRLNALAKEGVTTVEIKSGYGLDIETELKILRVARELGKHHHVDVKTTFLGAHAIPPEYKNDSDAYVDLVINEMLPQVIAENLADAVDVFCENIAFSLAQTERVLTAAKNAGLDIKLHAEQLSNLGGSEMAAKLGAKSVDHIEYLDEDGVKALSESGTCATLLPGAFYFLRETQLPPIELLRQYKVPMVVASDYNPGSSPLCSSLLMLNMACTLMRLTPEEALAGMTRNAAKALGIEAEVGVLETGMTADFCLWNISTPAELSYTYGVGSCIEVVKNGRLVHQ
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHER_VIBAN
Sequence: MTAITISDQEYRDFSRFLESQCGIVLGDSKQYLVRSRLSPLVAKFKLTSLSDLLRDVVTGRNRELRVAAVDAMTTNETLWFRDAYPFTVLAERLLPEVAANKRPIKIWSAASSSGQEPYSMAMTVLETQQRKPGMLPSVAITATDISASMLDMCKAGIYDNLALGRGLSPERRKIFFEDAGDGRMKIKDNVKRLVNFRPQNLMESYALLGKFDIIFCRNVLIYFSPDMKSKVLNQMASSLNPGGYLLLGASESLTGLTDKFEMVRCNPGIIYKLK
What is the function of this protein?
Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
What are the official names of this protein?
Chemotaxis protein methyltransferase.
Protein: RSMB_ENT38
Sequence: MKKQNLRSMAASAIEKVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLPQQEWLISKLMSRPMTGKQRTIHYLIMVGFYQLLHTRIPPHAALAETVEGAVVIKRPQLKGLINGVLRQFQRQQEELLAEFADSDKRFLHPEWLLKRLQKAYPSKWEAIVEANNQRPPMWLRVNRNHHTRDEWLALLETAEMNGFTHDAYPDAIRLASPAPVQALPGFEQGWVTVQDASAQGCMTYLEPQNGDHILDLCAAPGGKTTHILEIAPKASVMAVDVDEQRLSRVYDNLKRLGMKAEVKQGDGRTPGEWCGDEQFDRILVDAPCSATGVIRRHPDIKWLRRDRDINELAQLQSEILDAVWPHLKPGGTLVYATCSVLPEENSQQIAAFLKRTSNATLRTTGTPDKPGVQNLPGAEDGDGFFYAKLIKE
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_PHEZH
Sequence: MALPEFSMRQLLEAGAHFGHQTHRWNPKMDKYIFGARSNIHIIDLSQSIPLLHQALVKVREVAAGGGRILFVGTKRQASEPIATAAKRCAQYYVNHRWLGGTLTNWRTVSNSIARLRELESVLGGEGQGRSKKELLQLTRERDKLELSLGGIKDMGGIPDLMFVIDTNKEAIAIQEARKLNIPVIAILDTNCNPDGITYPIPGNDDAARAIQLYCDLMADAILDGLAAGQAASGVDLGASEAPVEPTLARELAPEAPAPEAPAEEAPAAEAAPAAEAAPAAEAAPAEASSEEQAG
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.