PharMolix/UniProtQA huggingface dataset:
Protein: DNAE2_PSEPF
Sequence: MNQGYAELHCLSNFSFQRGASSALELFQRAKKHGYQALAITDECTLAGIVRAWQAAKSVELPLIIGSEIRIENGPKLVLLVENIEGYQALCGLITQARRRTQKGQYQILREDFSEPLPGLLVLWVPEAVDEVEEGRWLKQTFGERLWLAVQLHRGQNDQQRLAALLSLADELQIPAVASGDVHMHARGRRALQDTMTAIRHHVPVAEAGLRLHPNGERHLRSLDVLRELYPQTLLDESLKLARRCTFDLGELRYQYPKELVPEEHSASSWLRHLTEQGIAWRWPKGAQPKVLKQIDDELELIAELGYESYFLTVHDVVRFAREQKILCQGRGSAANSAVCFALGITEIDPDRTTLLFERFMSRERNEPPDIDVDFEHERREEVLQYVFRRYGRRRAALTAVVSTYHASGAIRDVAKALGLPPDQINALADCCGHWSDETPPVERLREGGFDPESPLLHRVLSLTGQLIGFPRHLSQHPGGFVISEQPLDTLVPVENAAMADRTIIQWDKDDLDAVGLLKVDILALGMLSAIRRCFDLLRRHRHQDLSLATIPPEDRPTYDMISRADTIGVFQIESRAQMSMLPRLRPQTFYDLVIEVAIVRPGPIQGGMVHPYLRRRNKEEEETYPSPELEVVLKRTLGVPLFQEQVMQIAIVAADYSPGEADQLRRSMAAWKRHGGLEPHKERLAAGMKKNGYSPEFAAQIFEQIKGFGSYGFPESHAASFALLTYASCWLKCHEPAAFACALINSWPMGFYSPDQILQDARRHHLQIRPVDVRASDWDCSLEPIAGEQPAIRMGLRMIKGFREEDARSIEKARARGAFADVADLGERAGLDSRAQALLADAGALRGLAGHRHRARWEVAGVQKQLGLFAGLPSQEEPDVLLPTPSVSEDLFTDYATLGTTLGPHPLTLLRNELRARRCRSSRDLLEVEHGRPVSVAGLVTGRQRPGTASGVTFVTLEDEFGNVNVVVWRDLAERQRQVLVGSQLLKVDGRWEREGEVRHLIAGRLSDLTPLLNGIRVQSRDFH
What is the function of this protein?
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS).  It is not the major replicative DNA polymerase.
What are the official names of this protein?
Error-prone DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DER_STRT2
Sequence: MTLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYTSAEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAGIAMTEADVIVFVVSGKEGVTDADEYVARILYKTNKPVILAVNKVDNPEMRADIYDFYSLGLGDPYPVSSVHGIGTGDVLDAIVGNLPTEVEEENPDIIRFSLIGRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTNFVDSEGQEYTMIDTAGMRKSGKVYENTEKYSIMRSMRAIDRSDVVLMVINAEEGIREYDKRIAGFAHEAGKGIIIVVNKWDTIKKDNHTVANWEADIRDQFQFLSYAPIVFVSAKTKQRLNKLPEMIKRISESQNRRISSAVLNDVIMDAIAINPTPTDKGKRLKIFYGTQVSVKPPTFVIFVNEEELMHFSYMRFLENQIRQAFGFEGTPIHLIARKRK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: PLSY_SHEON
Sequence: MSQLSLTLLMIVAAYLAGSVSSAVLVCRMRGLPDPRSQGSGNPGATNVLRIGGASSAAMVLFFDMLKGALPTYLAYLMGIDAISLGLIAIAACLGHIYPVFFGFKGGKGVATAFGAMAPIGDDLAICLMASWVVLVLISRYSSLAAIITALLAPLYTWWLDDRFTIPVAMLSTLIIIRHKDNIKRLLKGEESKVSRKRRPKIP
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PROA_VIBCH
Sequence: MDLTVLGKAAKAASFQLATASTAQKNQALASMADQLEAQSASILAANAKDIALGREAGLSDAMLDRLLLNESRLQAIANDVRNVIKLNDPVGSEIDSRVLENGMSLARRRVPLGVVGVIYEARPNVTIDIAALCLKTGNAAILRGGKETFFSNMELVKVIQSALDKAGLPAASVQYIEKPDRELVTQLLKMDDYVDMIIPRGGAGLHKMCKENSTVPVIIGGFGISHIFVDESADLDKSVAVIENAKVQRPSACNALDTLLVHQAIAKPLLDKLIAKLNGKVAFVAEPKAKALMSSAAELRDAQAGDFDTEWLSYTLGVKVVQDVQEAIEHMREHNASHSDAIMTNDLYNAELFVNTAGSAAVYVNASTRFTDGAQFGLGAEVAVSTQKLHARGPMGLEELTSYKWVGKANYLSRS
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASP_AERSO
Sequence: MKQTSLALAITALLSTLPSALVQANEGCAPLTGKESGMDIGRSSTERCLPGANPLQDQQWYLLNSGQDGFSARGGIAGNDLNLWWAHRTGVLGQGVNVAVVDDGLAIAHPDLADNVRPGSKNVVTGSDDPTPTDPDTAHGTSVSGIIAAVDNAIGTKGIAPRAQLQGFNLLDDNSQQLQKDWLYALGDSNASRDNRVFNQSYGMSVVDPRSANSLDQSQLDRLFEQQTLKAQGAAYIKAAGNGFNKIAAGGYVLNRTGNGPKLPFENSNLDPSNSNFWNLVVSALNADGVRSSYSSVGSNIFLSATGGEYGTDTPAMVTTDLPGCDMGYNRTDDPSTNRLHGNSQLDASCDYNGVMNGTSSATPSTSGAMALLMSAYPDLSVRDLRDLLARSATRVDAKHQPVMVSYTSSTGKVRDVKGLEGWERNAAGMWFSPTYGFGLIDVNKALELAANHQPLPPLVQLPWQKINVTGSAAAIADVGNSPTSSTTRIATPLTVEAVQVMVSLDHQRLPDLLIELVSPAGTRSILLSPFNSLVGQSLDQQQLGFVRTKGLRDMRMLSNKFYGESAQGTWRLEVTDVANGTRQVSLLNRETRERTTLTERNNRQPGKLISWSLRVLGHDANRS
What is the function of this protein?
Exhibits serine protease activity (PubMed:11092244, PubMed:12153115, PubMed:16487335, PubMed:18067862, PubMed:18462393, PubMed:19654332).  Preferentially cleaves the peptide bond following two basic residues, one of which is Lys, but does not recognize the bond following a single basic residue (PubMed:16487335).  Probable potent virulence factor that cleaves various host plasma proteins, including prekallikrein, prothrombin and fibrinogen (PubMed:16487335, PubMed:17142774, PubMed:18067862, PubMed:18462393, PubMed:19654332).  ASP induces vascular leakage and reduction in blood pressure by activating the host plasma kallikrein/kinin system (PubMed:12153115, PubMed:16487335, PubMed:17142774).  It affects the host coagulation system during infection through activation of prothrombin to alpha-thrombin and degradation of fibrinogen, which impairs plasma clottability (PubMed:18067862, PubMed:18462393).  It also hydrolyzes the complement component C5, releasing the C5a anaphylatoxin, which causes the formation of pus and edema (PubMed:18714034).  In addition, degrades its external chaperone ORF2 after the secretion of the ASP-ORF2 complex (PubMed:25784551).
What are the official names of this protein?
Aeromonas extracellular serine protease, ASP, Lys-Lys/Arg-Xaa endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family. Furin subfamily.
Protein: P56_BPPZA
Sequence: MVQNDFLDSYDVTMLLQDDNGKQYYEYHKGLSLSDFEVLYGNTVDEIIKLRVDKIS
What is the function of this protein?
Inhibits the host uracil-DNA glycosylase (UDG), an enzyme which removes uracil residues from DNA by the base excision repair.  Interacts with host uracil-DNA glycosylase and prevents the latter from binding to DNA.  Since the viral DNA polymerase efficiently incorporates dUMP into DNA, the virus needs to prevent the deleterious effect caused by host UDG when it eliminates uracil residues present in the viral genome.
What are the official names of this protein?
Protein p56.
What is the protein family that this protein belongs to?
Belongs to the phi29likevirus protein p56 family.
Protein: OCTN2_HUMAN
Sequence: MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRCRVPDAANLSSAWRNHTVPLRLRDGREVPHSCRRYRLATIANFSALGLEPGRDVDLGQLEQESCLDGWEFSQDVYLSTIVTEWNLVCEDDWKAPLTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLVGMGQISNYVAAFVLGTEILGKSVRIIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLLVALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQDLSSKKQQSHNILDLLRTWNIRMVTIMSIMLWMTISVGYFGLSLDTPNLHGDIFVNCFLSAMVEVPAYVLAWLLLQYLPRRYSMATALFLGGSVLLFMQLVPPDLYYLATVLVMVGKFGVTAAFSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTLFLPESFGTPLPDTIDQMLRVKGMKHRKTPSHTRMLKDGQERPTILKSTAF
What is the function of this protein?
Retained in the ER, unable to perform carnitine uptake.
What are the official names of this protein?
Organic cation/carnitine transporter 2, High-affinity sodium-dependent carnitine cotransporter, Solute carrier family 22 member 5.
What is the protein family that this protein belongs to?
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
Protein: CMC17_EIMAC
Sequence: HAASPRGRPQQRSSRHGAEGPDTTRRGSCCSSSSSCCRPSTPRHPHNHECKRQLLLLGALLGLPSNTMKYVLVQKKKKK
What are the official names of this protein?
EAMZP30-47 protein.
What are the subcellular locations of this protein?
Membrane. Cell membrane. Cytoplasmic vesicle, secretory vesicle, rhoptry. Note=Surface membrane and internal rhoptries.
Protein: SCRK1_ORYSJ
Sequence: MAGRSELVVSFGEMLIDFVPTVAGVSLAEAPAFVKAPGGAPANVAIAVARLGGGAAFVGKLGDDEFGRMLAAILRDNGVDDGGVVFDAGARTALAFVTLRADGEREFMFYRNPSADMLLTHAELNVELIKRAAVFHYGSISLIAEPCRSAHLRAMEIAKEAGALLSYDPNLREALWPSREEARTKILSIWDQADIVKVSEVELEFLTGIDSVEDDVVMKLWRPTMKLLLVTLGDQGCKYYARDFRGAVPSYKVQQVDTTGAGDAFVGALLRRIVQDPSSLQDQKKLEEAIKFANACGAITATKKGAIPSLPTEVEVLKLMESA
What is the function of this protein?
Fructokinase that may play an important role in maintaining the flux of carbon towards starch formation.  May also be involved in a sugar-sensing pathway.
What are the official names of this protein?
Fructokinase-1, Fructokinase I, OsFKI.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family.
Protein: PDX1_PHAVU
Sequence: MEGEGSRVVALYDGNGAITETKKSPFSVKVGLAQMLRGGVIMDVVNADQARIAEEAGACAVMALERVPADIRAQGGVARMSDPQLIKEIKRAVTIPVMAKARIGHFVEAQILEAIGIDYVDESEVLTLADDANHINKHNFRIPFVCGCRNLGEALRRIREGAAMIRTKGEAGTGNIIEAVRHVRSVMSDIRVLRNMDDDEVFTFAKSIAAPYDLVMQTKQLGRLPVVHFAAGGVATPADAALMMQLGCDGVFVGSGVFKSGDPAKRARAIVQAVTHYSDPEILAEVSCGLGEAMVGINLSDTNVERFANRSE
What is the function of this protein?
Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia.  The ammonia is provided by PDX2.  Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.  Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PDX1, PLP synthase subunit PDX1, pvPDX1.
What is the protein family that this protein belongs to?
Belongs to the PdxS/SNZ family.
Protein: MENH_BACSU
Sequence: MGTVNITVSDGVRYAVADEGPNASEAVVCLHGFTGSKQSWTFLDEMLPDSRLIKIDCLGHGETDAPLNGKRYSTTRQVSDLAEIFDQLKLHKVKLIGYSMGGRLAYSFAMTYPERVSALVLESTTPGLKTLGERRERIMRDRKLADFILRDGLEAFVAYWENIPLFSSQQRLAEDIRYRIRSGRLRNNKIGLANSLTGMGTGSQPSLWSRVEEIDVPVLLICGEWDEKFCAINQEVHKMLPSSRIEIVPKAGHTVHVEQPRLFGKIVSEFLTSI
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
Putative 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: EX7S_SHISS
Sequence: MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDTSLPPFTPDNE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REX_STRSU
Sequence: ASSKEIAEAIGIDSATVRRDFSYFGELGRRGFGYNVKELMDFFADILNDTSITNVMLVGVGNMGRALLHYRFHERNKMKIVMAFEADDNPAVGTTDENIPIHAISEIKERISEANSQTAILTVPSVKAQEVTDILVEAGVKGILSFSPVNLSVPKDVVVQYVDLTSELQTLLYFMRKG
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KLEG1_ECOLX
Sequence: MRHSSLTPRGKSWPCSAPPWPSSRTGWACLPRRCASRRRWRAGRPCSTTRTGPRFARARWIPTTGDRRGRRPQRHRPSTRREQIFSR
What are the official names of this protein?
Putative protein KleG.
Protein: ARGR_LISMC
Sequence: MNKGHRHIIIRELITSNEIDTQEDLVELLLERDVKVTQATVSRDIKELHLVKVPTQTGGYKYSLPADNSFNPHQKLKRALIDCFIGIDNVQFMIILKVMPGNGNSVGALIDNLDWPEKAGTICGDDTCLIICRSEENAKTLTDRFIDML
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPT2_DANRE
Sequence: MDFDSVLSIASQNQGLSSLPKRYSLKTGPPKKDLKVGGVNSAAVQAFLKKKAVEQKNKEQQDKKAKEDLLAKRVELKSDRKARAMASRTKDNFRGYNGIPVIDQPKKRQSKGSSTEEQQSSTKYEGGDYDDEDNFDYEGTDSESEPSRPVKPQAISRPEYSNRVENKPKKLSAPARPASSSMNFADLLKLAEKKQFEPVELKVVKKTEERLRTAEEIRELEMERRVKKLDKGKDVRSDKNSGQKDSRSQTSSNPQKKHVDRDGKNGRFPRPSEEKHQSSSTSKKPKLQASSERTPTSAKLHGDRSNSGSSGALNSKSAMKNGASFQAKQAPPRPSQGQRPATPSDLTPRKGNVSLTQAKSSISGSCPPGAARPGQGPHKNSAHGRPSNFSTSGPSQKPANPGKLSRPGSNAPPRPGGSGVVRPFTGDPSKQPRPGGNLQSQQFPGSSRASLNGPKRMERGVSGSQINRMSSGPGRSQCTVVSETISTKNITPRPGMVQRPPGPQGPRTVIGPSGHRILVKPSGPALPPITSSYKRKFEDEEEYDSEMDDFIDDEGEDQDEISKHIREIFGYDKNKYKDESDYALKFMESSWKEQQKEEARSLRMAVLEDEEEERRELEEMQRKNAKKRK
What is the function of this protein?
Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin.  Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription.  Binds DNA and histones and promotes nucleosome assembly (in vitro).  Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (By similarity).  Modulates RNA polymerase 1-mediated transcription (By similarity).  Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (By similarity).
What are the official names of this protein?
Protein SPT2 homolog, SPT2 domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the SPT2 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: HBA_THEGE
Sequence: VLSPDDKKHVKDAWGKVGEHAGQYGAEALERMFLSFPTTKTYFPHFDLSHGSDQVKKHGKKVADALTLAVGHVDDMPQALSKLSDLHAHKLRVDPVNFKLLSHCLLVTLAAHLPAEFTPAVHASLDKFLASVSTVLTSKYR
What is the function of this protein?
Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1.  Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling.
What are the official names of this protein?
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: LPXD_AZOSB
Sequence: MFRLDELAARLGGDVVGDPATTVRRVATLEQAGEGDLSFLANPKYVGRLKSSHASAIIVADSARSLLGEKAGIVTRDPYLYFARVAQLFNPPEAVAPGVHPLADVAVAVPASVAVAAGASIGAGVELGEDVVIGAGSSIGAGVRIGAGTRLAPRVVIYPGCVIGTNCLIHAGAVIGSDGFGFAREKSGAWVKIPQVGRVVIGDDVEIGANTTIDRGALDDTVIGNGVKIDNQIQIGHNVRIGDYTAIAGCVGIAGSTQIGARCMIGGQAGIIGHLTIADDVVISAGTLVTKSIHKPGVYTANLPVQPHADWVKNFAHLRHLDSLAARIRALEQSPDHPESA
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: YCIB_YERPA
Sequence: MKQLLDFLPLVVFFIFYKMYDIFVASGALIVATLVALAFTWLKYRKVEKMTLVTAAMVLVFGTLTLAFHSDLFIKWKVTVLYVLFALALLVSQWVMKKPLIQRMLGKELTLPDKVWSTLNLSWAIFFLVCGLLNIYVAFWLPQDIWVNFKVFGLTALTLIFTLISGVYIYRHMPEEQKKS
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRG_RHOP2
Sequence: MARYIFITGGVVSSLGKGLASAALGALLQARGYKVRLRKLDPYLNLDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFTGRPATRQDNITTGRIYQDILTKERRGDYLGATIQVVPHVTNAIKDFIVDSNDGYDFVLVEIGGTVGDIEGLPFFEAIRQIKNDLPRGDVIYIHLTLLPYIPSAGELKTKPTQHSVKELRSIGIQPDILLCRTDRPIPKEERRKLGLFCNVRESAVIEARDADSIYAVPEAYHAAGLDDEVLAAFAIAAEQPPALERWHQINERIRNPEGAVTIAIVGKYTGMKDAYKSLIEALSHGGIANKVQVKLDWIESEVFENEDPAPFLEHVNGILVPGGFGQRGAEGKIKAAQFARERDVPYFGICFGMQMAVIEAARNLAGIEQANSTEFGPTAEPLVGLMTEWLRGNELERRSNAGDLGGTMRLGAYPAALKRGSRVSKIYGDVLEISERHRHRYEVNTAYKDRLEQHGLRFSGMSPDGVLPEIVEYEDHPWFIGVQFHPELKSRPFEPHPLFSSFIEAALVRSRLV
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: HIS1_PSEE4
Sequence: MLTIALSKGRILDDTLPLLAEAGIVPTENPDKSRKLIIPTTQDDVRLLIVRATDVPTYVEHGAADLGVAGKDVLMEYGGQGLYEPLDLQIAQCKLMTAGVTGAPEPKGRLRVATKFVNVAKRYYAEQGRQVDIIKLYGSMELAPLINLADKIIDVVDTGNTLRANGLEPQELIATISSRLVVNKASMKMQHARIQSLIDTLRNAVESRHRG
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_FRATM
Sequence: MARLKDYYQKKLVAKLKTELGLDNIMEVPAIKKITLNMGVGDAAKDKKIMTFALNDLTAIAGQKPVVTKSKKSIAGFKIRDGWPIGAKVTLRGDRMYEFLDRLITIAIPRIRDFRGLSAKSFDGRGNYSLGMREQISFPEIDYDKVDSIRGLDISITTTAKNDDQGRALLKAFGFPFKS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: YPI_BPPRD
Sequence: MTENIISWNVANWVTVILMALAGYAVLALAAKVINNRAQEPA
What are the official names of this protein?
Putative uncharacterized 4.5 kDa protein in genes IX-XX intergenic region, ORFi.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: DMBT1_PIG
Sequence: MGTSAVILEICLLLSQVLTTVSSTTQTESTTEDRTQITETAFWETQTINSVSESDLPGTHASSFHTEEPLTTIAAEGTEWDLALRLVNGGDRCQGRVEILYQGSWGTVCDDSWDTNDANVVCRQLGCGWAVSAPGSARFGQGLGPILLDDLRCSGHETYLWSCPHSGWKTHNCGHQEDAGVICSGAQRSSTVIPDWWYTTTRSQTAHIRSTIPAWWHPTTTTAARTEWDLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAVSAPGSARFGQGSGPILLDDLRCSGHETYLWSCPHSGWNTHNCGHHEDAGVICSDAQRSSTVIPDWWYTTTPSQTAHIRSTIPAWWHPTTTTAARTEWDLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAVSAPGSARFGQGSGPILLDDLRCSGHETYLWSCPHSGWNTHNCGHHEDAGVICSDAQRSSTVIPDWWYTTTPSQTWWHPTTTTAASPSSPCGGFLTSASGTFSSPSYPGLYPNNANCVWEIEVNSGYRINLGFNNLQLEVHINCIYDYIEIFDESPGSNTSLGKICNHTSQIFTSSYNRMTVRFRSDGSVQKPGFSAWYNSFPRDASLRLVNSNSSYPSCAGRVEIYQGGRWGTVCDDGWDIQDAQVVCRQLGCGNAVSAPGNAYFGPGSGPITLDDVACSGTESTLWQCRNRGWFSHNCGHSEDAGVICSVPAFTTTPPATNYSCGGFLSQAAGGFNSPFYPGNYPNNANCVWDIEVQNNYRVTVVFRDVQLESGCNFDYIEVFDGPYRSSPLLARVCNGASGSFTSSSNFMSIRFISDVSVTRAGFRANYYSSPSSGSTRLHCLQNHMQASVSTSYLQSLGYSARDLVIPGWEWSYQCQPQITSTQVTFTIPYSSCGTIQRVDNDTITYSNSLRAAVSSGIIKRKKDLNMYVSCRMLQNTWVNTVYIANDTLEVQNVQYGNFDVNISFFTSSSFLYPVRSSPYYVDLNQNLYLQAELLHANASLALFVDTCVASPYPNDFTTLTYDLIRSGCVKDETYQSYSQPSPRIVRFKFSSFHFLSRFPSVYLQCKMVVCRAFDSSSRCRRGCVVRSKRDVGSYQEKVDVVLGPIQLQTLHAEKRSLDQPAVDLEEKASAQGSYDGAAISAGIFLVVVLAVAAFTLGRRGRAADGQPLISKT
What is the function of this protein?
May play roles in mucosal defense system and cellular immune defense.  May play a role in liver regeneration.  May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage.  May function as a binding protein in saliva for the regulation of taste sensation.  May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract.  Required for terminal differentiation of columnar epithelial cells during early embryogenesis.  Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens.  Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity.  Inhibits cytoinvasion of S. enterica.  Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis.  Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell (By similarity).
What are the official names of this protein?
Deleted in malignant brain tumors 1 protein, Hensin.
What is the protein family that this protein belongs to?
Belongs to the DMBT1 family.
What are the subcellular locations of this protein?
Secreted. Cytoplasmic vesicle, secretory vesicle membrane; Single-pass membrane protein; Lumenal side. Note=Localized to the lumenal aspect of crypt cells in the small intestine. In the colon, seen in the lumenal aspect of surface epithelial cells (By similarity). Formed in the ducts of von Ebner gland and released into the fluid bathing the taste buds contained in the taste papillae (By similarity).
Protein: MRAY_CHLTE
Sequence: MLYYILRYINELYSLPGMGVIEYLTFRASAAAITALLIIIFAGQRFIRFLKSKFVEPIKEEAPPEHRKKKDVPTMGGLMIIFAIEVSAFLWAKIDDPHVWLIMLAVFWMGLIGFIDDYQKVVLKVKGGLAGHYKLIGQVTLGLVIGFYTWNDPVFSVLLSDTTVPFFKKLSVDYGIFYIPVVIFIITAVSNAVNLTDGLDGLAAGNAAIVTFALGVFAYLCGNAVYSGYLSIPFISGAGEVAVVSMAIVMACVGFLWFNSSPAEVFMGDTGSLSLGSAIAVIALMIKQELLLPVLAGVFFVETLSVSMQVAWFKISKKLYGEGRRIFLMAPLHHHFQLKGWAEQKIVIRFWIISILLFLTSLMTLKLR
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.