PharMolix/UniProtQA huggingface dataset:
Protein: VP3_ROTH6
Sequence: MKVLALRRSVAQVYADTQIYTHDETKDDYENAFLISNLTTHNILYLNYSVKTLQILNKSGIAAVEIQKMDELFTLIRCNFTYDYIEDIVYLHDYSYYTNNEIRTDQHWVTKTNIENYLLPGWKLTYVGYNGNDTRGHYNFSFKCQNAATDDDAIIEYIYSNELDFQNFILKKIKERMTTSLPIARLSNRVFRDKLFKTLVSDYSKVVNVGPRNESMFTFLDHPSIKQFSNGPYLVKDTIKLKQERWLGKRLSQFDIGQYKNMLNVLTTLYQYYDMYHEKPIIYMVGSAPSYWIHDVRQYSNLKFETWDPLDTPYSDLHHKELFYISDVTKLKDNSILYVDIRTDRESIDWKTWRKIVEEQTINNLNIAYRYLSTGKAKVCCVKMTAMDLELPISAKLLHHPTTEIRSEFYLIMDIWDSKNIKRFIPKGVLYSYINNIITENVFIQQPFKLKTLRNEYVVALYALSNDFNNREDVIKLVNNQKNALITVRINNTFKDEPKVGFKDIYDWTFLPTDFETNESIITSYDGCLGMFGLSISLASKPTGNNHLFILSGTNKYFKLDQFANHMSISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYSFDLKRWIYLHSTNKASIEGGRYYEHAPIELIYACRSAREFARLQDDLTVLRYSNEIENYINKVYSITYADDPNYFIGIKFKNIPYEYDVKVPHLTFGVLNISDSMVPDVIAILKKFKSELFRMDITTSYTYMLSDEIYVANVSGVLSTYFKLYNAFYKEQITFGQSRMFIPHITLSFSDKKVVRIDSTRLNIDFIYLRKIKGDTVFDMAE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: SYK_STRPN
Sequence: MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQELKDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEENYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETIYRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFITHHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVDFWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVSPLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATGIDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y257_BUCAP
Sequence: MHISMFDFSIYIKFFVSLCALVNPIGMIPIFTTMTNHQSHLERKKTNLVANFSAFIILLISLFAGNSILNAFGISINSFRIAGGILIISIAFSMISGKFTKNNKTSKEKNQENISVVPLAMPLIAGPGAISSTIVWSTYYSTWSDFLGCSIAIFLFAFVCWLCFRAAPCVVEILGKTGINIITRIMGLLLMSLGIEFLSIGIKSIFSALLH
What are the official names of this protein?
UPF0056 membrane protein BUsg_257.
What is the protein family that this protein belongs to?
Belongs to the UPF0056 (MarC) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: AMPA_ACTPJ
Sequence: MEFSVKNGSVEKQRTACLVVGVYEPRRLSAAAEQLDKLSEGYISTLLRRGDLEGKAGQTLLLHNVPNVPADRVLLVGCGKERELTERQYKQIIQKMVQAVSETGSMEVVCFLTELHVKGRTSYWNVRFAIEAIQESLYSYNDFKSIKPEVRREFRRVIFNVANRKDLADAERALEQGKAISTGVAFAKNVANCPPNVCNPAYLAELAKGLAAEYDNIRTTVIDEAEMAALGMNAYLAVSRGSQNPAYLSVIEYKNHPNPDAKPIVLVGKGLTFDSGGISIKPSDSMDEMKYDMGGAASVYGTMKALAEMKLPLNVIGVLAGCENMPDGNAYRPGDILTTMNGLTVEVLNTDAEGRLVLCDTLTYVERFEPELVIDMATLTGACMIALGAHNSGLMSTSNVLANDLLNAAEQADDKAWRLPLGEEYQEQLKSNFADLANIGGRLGGAITAGQLLSNFTKKYVWAHLDIAGTAWKSGVAKGATGRPVSLLSQFLINKANNQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPEL3_CHLAE
Sequence: MVRISKPKTFQAYLDDCHRRYSCAHCRAHLANHDDLISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIHCENCKTTLGWKYEQAFESSQKYKEGKYIIELNHMIKDNGWD
What are the official names of this protein?
Protein yippee-like 3.
What is the protein family that this protein belongs to?
Belongs to the yippee family.
Protein: MATK_OENAR
Sequence: MEEFPGYFELDRSRQHDFLYPLIFRESIYALAHDHGLNRNRSTLFENEVDYDKKYSLIIVKRLITRMYQRNHLIISANGSVQNPFWGHNKNLYSKILSEGFAVIVEIPFSLRVLSSFERKEKDIAKSPTLRSIHSIFPFLEDQFSHLDYLSHVLIPYPIHLEIAVQTLRYWVKDASSLHLLRIFLHEYWNSFSTPKKHITLFLKGNSRFFLFLYNSYVCEYESIFLFIRNQSSHFQSTSSGVFFERILFYVKIDHLVEVFVGTDFLDIRSFFKDPNMHYVRYQGKSILASKDTPLLMNKWKYYLVNLWQYHFSVWSQPGRININQLGKYSLDFLGYFSNVQLKSSVVRNQTLENSFLINNAMKKLETTVPILPLIGSLSRAKFCNALGHPISKPTRTDSSDSDIIDRFVRICRNLSHYHSGSSKKKSLYRIKYILRLSCVKTLARKHKSSVRAFLKRLGSELGDEFLTEEGVVLAVIFPKASGRLYRGRIWYLDIPCINDWVGDAEGSIFTK
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RBL_GAREL
Sequence: VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVVGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPVAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAINKAQAETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREACKWSPELAAACEVWKAIKFEF
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ATG15_KLULA
Sequence: MKPGIKISKRYSARNASVITVLLLLIYLIYINKETIQTKYQGSRINHDSGGDSTKDKTHTFTIKEIHFRPLDEKTQSYGSLQVTPEFVNMAKSEFEQNVAVASGDNEDLYDKQLWSASIKSNPWTHQFTLKQGSIKMKRMVNRDPDYVESFLDYAHENPEMARKVHLDWVDESVLAPNVTDKETVISLALMSSNAYVRLPYEGDWRNLSDWNNDLNPDLSVGIGWDSDGVRGHIFSNDDSSVIVIALKGTSAQGLPGSGEDETTDNDKLNDNVLFSCCCARVSYLWKTACDCYVKSYTCDEKCLEQELVRKDRYYQAVLDIYRSVVTAHPNSAIWITGHSLGGALASLLGRTFGAPAVAFEAPGELLATKRLHLPMPPGLPAYQEGVWHIGHTADPIFMGTCNGASSSCSIAGYAMETSCHSGKVCVYDVVTDKGWHVNMLNHRIHTVIDGILTDYDTVAKCKTPDACHDCFNWNYVKGRDVPKKHKSSSSTASSTSAETSTLTVGPSPPEKTTTSCIGRNWIGICTEYGI
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase ATG15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: END4_YERPB
Sequence: MKFVGAHVSAAGGVDQAVIRAHELEATAFALFTKNQRQWRAAPLAEDVIEKFKLACEKYGYTSAQILPHDSYLINLGHPVTEALEKSREAFIDELVRCQQLGLSLLNFHPGSHLLQIDEDQCLARIAESINIALDATEGVTAVIENTAGQGSNLGFKFEHLAAIIERVEDKSRVGVCIDTCHAFAAGYDLRTEEDCEHTFAALGKIVGFQYLRGMHLNDAKSEFNSRVDRHHSLGEGNIGKTVFSYIMRDSRFDNIPLILETVNMDIWAEEIAWLKSQAEIEPSL
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: LMBD2_REOVL
Sequence: MANVWGVRLADSLSSPTIETRTRHYTLRDFCSDLDAVAGKEPWRPLRNQRTNDIVAVQLFRPLQGLVLDTQFYGFPGIFSEWEQFIKEKLRVLKYEVLRIYPISNYNHERVNVFVANALVGAFLSNQAFYDLLPLLVINDTMINDLLGTGAALSQFFQSHGEVLEVAAGRKYLQMKNYSNDDDDPPLFAKDLSDYAKAFYSDTFETLDRFFWTHDSSAGVLVHYDKPTNGNHYILGTLTQMVSAPPHIINATDALLLESCLEQFAANVRARPAQPVARLDQCYHLRWGAQYVGEDSLTYRLGVLSLLATNGYQLARPIPKQLTNRWLSSFVSQVMSDGVNETPLWPQERYVQIAYDSPSVVDGATHYGYVRRNQLRLGMRVSALQSLSDTPAPIQWLPQYTIEQAAVDEGDLMVSRLTQLPLRPDYGSIWVGDALSYYVDYNRSHRVVLSSELPQLPDTYFDGDEQYGRSLFSLARKIGDRSLIKDTAVLKHAYQAIDPNTGKEYLRAGQSVAYFGASAGHSGADQPLVIEPWTQGKISGVPPPSSVRQFGYDVAKGAIVDLARPFPSGDYQFVYSDVDQVVDGHDDLSISSGLVESLLDSCMHATSPGGSFVMKINFPTRTVWHYIEQKILPNITSYMLIKPFVTNNVELFFVAFGVHQQSALTWTSGVYFFLVDHFYRYETLSTISRQLPSFGYVDDGSSVTGIEMISLENPGFSNMTQAARVGISGLCANVGNARKLISIHESHGARVLTITSRRSPASARRKARLRYLPLVDPRSLEVQARTILPSNPVLFDNVNGASPHVCLTMMYNFEVSSAVYDGDVVLDLGTGPEAKILELIPPTSPVTCVDIRPTAQPSGCWNVRTTFLELDYLSDGWITGIRGDIVTCMLSLGAAAAGKSMTFDAAFQQLVKVLTKSTANVLLIQVNCPTDVIRTIKGYLEIDQTNKRYRFPKFGRDEPYSDMDSLERICRAAWPNCSITWVPLSYDLRWTKLALLESTTLSSASVRIAELMYKYMPVMRIDIHGLPMEKQGNFIVGQNCSLTIPGFNAQDVFNCYFNSALAFSTEDVNSAMIPQVTAQFDANKGEWSLDMVFSDAGIYTMQALVGSNANPVSLGSFVVDSPDVDITDAWPAQLDFTIAGTDVDITVNPYYRLMAFVRIDGQWQIANPDKFQFFSSSTGTLVMNVKLDIADRYLLYYIRDVQSRDVGFYIQHPLQLLNTITLPTNEDLFLSAPDMREWAVKESGNTICILNSQGFVPPQDWDVLTDTISWSPSLPTYVVPPGDYTLTPL
What is the function of this protein?
Outer capsid protein involved in mRNA capping.  Catalyzes the last 3 enzymatic activities for formation of the 5' cap structure on the viral plus-strand transcripts, namely the RNA guanylyltransferase, RNA-7N- and RNA-2'O-methyltransferase activities (By similarity).
What are the official names of this protein?
Outer capsid protein lambda-2, Lambda2, Lambda2(Cap).
What is the protein family that this protein belongs to?
Belongs to the orthoreovirus lambda-2 protein family.
What are the subcellular locations of this protein?
Virion.
Protein: ACTS_PONAB
Sequence: MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, alpha skeletal muscle, Alpha-actin-1.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FAH2A_HUMAN
Sequence: MLVSGRRRLLTVLLQAQKWPFQPSRDMRLVQFRAPHLVGPHLGLETGNGGGVINLNAFDPTLPKTMTQFLEQGEATLSVARRALAAQLPVLPRSEVTFLAPVTRPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSIVGPYDEVVLPPQSQEVDWEVELAVVIGKKGKHIKATDAMAHVAGFTVAHDVSARDWQMRRNGKQWLLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFYPGDVILTGTPPGVGVFRKPPVFLKKGDEVQCEIEELGVIINKVV
What is the function of this protein?
May have hydrolase activity.
What are the official names of this protein?
Fumarylacetoacetate hydrolase domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the FAH family.
Protein: GLO2_PSEA8
Sequence: MIQIDALPAFNDNYIWLLQDATSRRCAVVDPGDAKPVEAWLAAHPDWRLSDILVTHHHHDHVGGVAALKELTGARVLGPANEKIPARDLALEDGERVEVLGLVFEIFHVPGHTLGHIAYYHPAETPLLFCGDTLFAAGCGRLFEGTPAQMHHSLARLAALPANTRVYCTHEYTLSNLRFALAVEPDNAALRERFEEATRLRERDRITLPSEISLELSTNPFLRVSEKSVKKKADQRSGQQNRTPEEVFAVLRAWKDQF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: YCF4_SOLBU
Sequence: MTWRSDDIWIELITGSRKISNFCWALILFLGSLGFLLVGTSSYLGRNLLSFFPPQQIIFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGKNRRIFLRFLIKDIQSVRIEVKEGIYARRVLYMDIRGQGSIPLTRTDENLTPREIEQKAAELAYFLRVPIEVF
What is the function of this protein?
Seems to be required for the assembly of the photosystem I complex.
What are the official names of this protein?
Photosystem I assembly protein Ycf4.
What is the protein family that this protein belongs to?
Belongs to the Ycf4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: QUEC_BACLD
Sequence: MKQEKAIVVFSGGQDSTTCLLWALRQFQEVEAVTFQYNQRHKQEIEVAKKIAAKLGVKHHLLDMELLNQLAPNALTRDDIEIEAKEGELPSTFVPGRNLVFLSFASILAYQVGARHIITGVCETDFSGYPDCRDEFVKSCNVTVNLAMERPFVIHTPLMWLNKAETWELADELDALDFVKNETLTCYNGIIADGCGECPACKLRANGYNEYMKMKKERA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RADA_SULIK
Sequence: MSNEVEQKKSIKTINDLPGISQTVINKLIEAGYSSLETLAVASPQDLSVAAGIPLSTAQKIIKEARDALDIRFKTALEVKKERMNVKKISTGSQALDGLLAGGIETRTMTEFFGEFGSGKTQLCHQLSVNVQLPPEKGGLSGKAVYIDTEGTFRWERIENMAKALGLDIDNVMNNIYYIRAINTDHQIAIVDDLQELVSKDPSIKLIVVDSVTSHFRAEYPGRENLAVRQQKLNKHLHQLTRLAEVYDIAVIITNQVMARPDMFYGDPTVAVGGHTLYHVPGIRIQLKKSRGNRRIARVVDAPHLPEGEVVFALTEEGIRDAEE
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  Binds and assemble on single-stranded DNA to form a nucleoprotein filament.  Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
What are the official names of this protein?
DNA repair and recombination protein RadA.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family.
Protein: APOA1_PHOVI
Sequence: MKAVVLTLAVLFLTGSQARHFWQQDEPQSPWDRVKDLATVYVDVVKDGGRDYVAQFEASALGKQLNLKLLDNWDSLSSTVAKLREQIGPVTQEFWDNLEKETEVLRQEMNKDLEEVKKKVQPYLDEFQSKWHEEVELYRQKVAPLGAELREGARQKLQELQEKLSPLGEELRDRARTHVDALRAQLAPYSEQLRERLAARLQALKEGGGATLTEYHAKASEHLSALREKAKPALEDLRQGLMPVLESFRASLLAAVDEATKKLNAQ
What is the function of this protein?
Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).  As part of the SPAP complex, activates spermatozoa motility (By similarity).
What are the official names of this protein?
Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A1/A4/E family.
What are the subcellular locations of this protein?
Secreted.
Protein: OSB12_DICDI
Sequence: MSTETETHLGESKRVILSSLIKQLSPNKEIKHMVLPCFLLQPRSTLESFTDMFTYIDELYKINEIDDEGERFLQFVKFYLTGWHTRPKGICKPFNPVIGEEFECFWSNNKNEDLPHIDELIEDNNSDVGVFKAEQISHHPPLSAYVFYNKFQKILVNGNICPSYVKFMGNSAESHLQGILEFNFFKWNECFECTLPTVGVKGIILGKLSPFTCGDIEIKSKNSKYSCKLEFLFKGLFGSSKNINGIKGTILYDNKPIYKVRGNWDKQIFIKKINEIAGTHGGSSSGSHTNSTERCLMDVSLLKNSKEKYTKPIEQQPPNSSYHLWELVTKNINNNNDKETAEEKAKIEEKQRKEESERREKGILWEPKEFHFKENPNNEYKTTFYYNDIPKLFDNLQSKPIQ
What are the official names of this protein?
Oxysterol-binding protein 12, OSBPl.
What is the protein family that this protein belongs to?
Belongs to the OSBP family.
Protein: MT1_DROAN
Sequence: MPCPCGSGCKCASQATKGSCNCGSDCKCGGDKKSACGCSK
What is the function of this protein?
This protein binds cations of several transition elements.  It is thought to be involved in detoxification processes.
What are the official names of this protein?
Metallothionein-1, MT-1.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 5 family.
Protein: YFCN_ECO24
Sequence: MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKISEVPVKRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPKEYGGDAALLVLIEVEEWLPPELP
What are the official names of this protein?
UPF0115 protein YfcN.
What is the protein family that this protein belongs to?
Belongs to the UPF0115 family.
Protein: TRUB_ECO24
Sequence: MSRPRRRGRDINGVLLLDKSQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLFIRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: CTHB5_CONVC
Sequence: MVMPLVLSLALTPPPLCHATLVDPRTTLQCHVRSYTFRATKPPIVNENGDPVTCQGDVRVSSCWGRCDSSEIGDYKMPFKISNHPVCTYTGRVSRTVRLSQCAGYPDPTVQVFDATGCACQFCNSETQLCEKLNG
What are the official names of this protein?
Thyrostimulin beta-5 subunit.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: NPY_PAROL
Sequence: MHPNLVSWLGTLGLLLWALLCLSALTEGYPVKPENPGDDAPAEELAKYYSALRHYINLITRQRYGKRSSPEILDTLVSELLLKESTDTLPQSRYDPSLW
What is the function of this protein?
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
What are the official names of this protein?
Pro-neuropeptide Y.
What is the protein family that this protein belongs to?
Belongs to the NPY family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEA_LEVBA
Sequence: MAYTLDDFDYDLPHELIAQTPIKQRDTSRLLVLDHQANTLEDKHFYDILDELHAGDAVVMNNSRVMPARLYGIKPETGGHVEVLLLHNVEGDVWETLMKPAKRLRVGTTVTFGDGQLTATVTEEREDGIRLIEFHYDGIFMEILEQLGETPLPPYIKEKLDDPDRYQTVYAKENGSAAAPTAGLHWTQELLDQVAAKGVKLVYITLHVGLGTFRPVEEANIEDHKMHSEFYRLDEAAAATLNEVRANGGRIIATGTTSIRTLETIGTKFKGEIKPDSGWTDIFIKPGYQWQVVNAFITNFHLPKSTLVMLVAAFTGRDQILNAYHHAIEEKYRFFSFGDAMFIK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZHX1_PANTR
Sequence: MASRRKSTTPCMVLASEQDPDLELISDLDEGPPVLTPVENTRAESISSDEEVHESVDSDNQQNKKVEGGYECKYCTFQTPDLNMFTFHVDSEHPNVVLNSSYVCVECNFLTKRYDALSEHNLKYHPGEENFKLTMVKRNNQTIFEQTINDLTFDGSFIKEENAEQAESTEVSSSGISISKTPIMKMMKNKVENKRIAVHHNSVEDVPEEKENEIKPDREEIVENPSSSASESNTSTSIVNRIHPSTASTVVTPAAVLPGLAQVITAVSAQQNSNLIPKVLIPVNSIPTYNAALDNNPLLLNTYNKFPYPTMSEITVLSAQAKYTEEQIKIWFSAQRLKHGVSWTPEEVEEARRKQFNGTVHTVPQTITVIPTHISTGSNGLPSILQTCQIVGQPGLVLTQVAGTNTLPVTAPIALTVAGVPSQNNIQKSQVPAAQPTAETKPATAAVPTSQSVKHETALVNPDSFGIRAKKTKEQLAELKVSYLKNQFPHDSEIIRLMKITGLTKGEIKKWFSDTRYNQRNSKSNQCLHLNNDSSTTIIIDSSDETTESPTVGTAQPKQSWNPFPDFTPQKFKEKTAEQLRVLQASFLNSSVLTDEELNRLRAQTKLTRREIDAWFTEKKKSKALKEEKMEIDESNAGSSKEEAGETSPGDESGAPKSGSTGKICKKTPEQLHMLKSAFVRTQWPSPEEYDKLAKESGLARTDIVSWFGDTRYAWKNGNLKWYYYYQSANSSSMNGLSSLRKRGRGRPKGRGRGRPRGRPRGSKRINNWDRGPSLIKFKTGTAILKDYYLKHKFLNEQDLDELVNKSHMGYEQVREWFAERQRRSELGIELFEENEEEDEVIDDQEEDEEETDDSDTWEPPRHVKRKLSKSDD
What is the function of this protein?
Acts as a transcriptional repressor.  Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA.  May link molecule between DNMT3B and other co-repressor proteins (By similarity).
What are the official names of this protein?
Zinc fingers and homeoboxes protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZHX family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalized in the nucleus with DNMT3B.
Protein: Y1467_BACCQ
Sequence: MAKIGVENSLTDVQQALQQQGHEVITINSEHDAQGCDCCVVTGQDSNMMGIADTSIKGSVINAHGLTTDEICQQVESRI
What are the official names of this protein?
UPF0180 protein BCQ_1467.
What is the protein family that this protein belongs to?
Belongs to the UPF0180 family.
Protein: CSTP1_HUMAN
Sequence: MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTEYFNSVCQGTHILFREFSFVQATPHNRVSFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKAARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYEDLLSGKNPNTVIVPTSSSGQHRQRPALGGAGTLEGVEASLFYQCLENLCDRHKYSCPPPALVKEALSNVQRLTFYGFLMALSKHRGINQALGALPDKGDLMHDPAMDEELERLLAQVPGLVNSVTASPEASCLPSRTPPRVGSPWRPLHHSRKVDGESDGSTEETDESET
What is the function of this protein?
Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly (PubMed:34782749).  Regulates the assembly and stability of the TPGC and thereby modulates polyglutamylation of the microtubule, which antagonizes MAP4 binding (PubMed:34782749).
What are the official names of this protein?
Centriolar satellite-associated tubulin polyglutamylase complex regulator 1.
What is the protein family that this protein belongs to?
Belongs to the CSTPP1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Cytoplasm, cytoskeleton. Note=Associated with microtubules.
Protein: LYSAC_SALTY
Sequence: MSQQGLEALLRPKSIAVIGASMKPHRAGYLMMRNLLAGGFNGPVLPVTPAWKAVLGVMAWPDIASLPFTPDLAILCTNASRNLALLDALGAKGCKTCIILSAPTSQHEELLACARHYKMRLLGPNSLGLLAPWQGLNASFSPVPIKQGKLAFISQSAAVSNTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFVSAARSASRNKPILVIKSGRSPAAQRLLNTSAGMDPAWDAAIQRAGLLRVQDTHELFSAVETLSHMRPLRGDRLMIISNGAAPAALALDELWSRNGKLATLSEETCLQLRQALPAHIDIANPLDLCDDASSEHYVKTLDILLASQDFDALMVIHSPSAAAPGTESAHALIETIKRHPRGKFVTLLTNWCGEFSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLRETPALPSNLTSNTAEAHNLLQRAIAEGAASLDTHEVQPILHAYGLHTLPTWIASDSAEAVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTASEVQQAANAIFDRVKMAWPQARIHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEGGVEWRPEEQAVVALPPLNMNLARYLVIQGIKQRKIRARSALRPLDIVGLSQLLVQVSNLIVDCPEIQRLDIHPLLASASEFTALDVTLDIAPFDGDNESRLAVRPYPHQLEEWVEMKNGDRCLFRPILPEDEPQLRQFIAQVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRMDNAEEILGVTRAISDPDNVDAEFAVLVRSDLKGLGLGRRLMEKLIAYTRDHGLKRLNGITMPNNRGMVALARKLGFQVDIQLEEGIVGLTLNLAKCDES
What is the function of this protein?
Acetylates and inactivates the acetyl-CoA synthase (Acs).  Can also acetylate other central metabolic enzymes in response to environmental changes.
What are the official names of this protein?
Peptidyl-lysine N-acetyltransferase Pat, Protein lysine acetyltransferase.
What is the protein family that this protein belongs to?
In the central section; belongs to the acetate CoA ligase beta subunit family.