PharMolix/UniProtQA huggingface dataset:
Protein: DNJ20_ARATH
Sequence: MKCYKSSSILSTNHHPFFYKQQPISSLQPTSIPTTISYPTRTRFSSTRIQSRLTHDDPVKQSEDLSFYDLLGVTESVTLPEIKQAYKQLARKYHPDVSPPDRVEEYTDRFIRVQEAYETLSDPRRRVLYDRDLSMGFSFSFSGRRQNRYDQEVVEEKSEWKAKWQTQLSGLRRRSNQKDNNTMSWAARMRRQQQESS
What is the function of this protein?
Plays a continuous role in plant development probably in the structural organization of compartments.
What are the official names of this protein?
Chaperone protein dnaJ 20, chloroplastic, AtDjC20, AtJ20.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family. C/III subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RS11_MYXXD
Sequence: MADEINTSAAASTGAEGEAPAAKKSKRKGKKNILNGVVHIQSTFNNTIITITDVSGNVISWSSAGARGFKGSRKSTPFAAQVAAGDAAAKAMEHGLKNVSVFVKGPGAGRESALRALAAAGLKINLIRDVTPIPHNGCRQPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PETN_THAPS
Sequence: MDIISLGWAGVMTMFTFSLALVVWGRNGF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein.
Protein: CYB_VIRFL
Sequence: MALNLRKNHPLLKIVNDSLIDLPTPSNISTWWNFGSLLGICLVTQIVTGLLLATHYTADTSLAFNSVAHMCRNVQFGWLIRNLHANGASFFFICIYLHIGRGLYYGSYLNKETWNVGVILLLTLMATAFVGYVLPWGQMSFWGATVITNLFSAIPYIGQTLVEWAWGGFSVDNPTLTRFFALHFLLPFVIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYTIKDILGFALMLTSLVALALFSPNLLGDPENFTPANPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASILVLFLMPLLHTSKQRSMTFRPLSQILFWVLVANLLVLTWIGSQPVEQPFIIIGQLASLSYFTIILVLFPIAGVLENKLLKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MINE_CHLAD
Sequence: MSFLNGLFGRKRDSSAELAKQRLLTVLIDDRYKLTPEMMAQMKADLAEVLKRYLPAIDAEQIEVTLSRGEAHDLLKADVPLRRTSEGPSNR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: MC5R_PANTR
Sequence: MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPRASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSCFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  This receptor is a possible mediator of the immunomodulation properties of melanocortins.
What are the official names of this protein?
Melanocortin receptor 5, MC5-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMG_ACIC5
Sequence: MPLIEQYDVVVVGAGHAGCEAAMAAARMGLRTALFTLNLDLIAQMSCNPAVGGIAKGHLVREVDALGGIMGELADAVGIQFRLLNTSRGPAVWSPRAQCDKQQYRVKMREVLESQPNLYIKQAEAVDVVVEDARVTGIRLRDGRTIRAGATVITTGTFLNGLIHCGEERIPAGRSGEPPSVLLGESLKQLGLRGCRLKTGTPPRLDGRTIDWARFEEQPGDADPTPFSFRTKTLPMRQISCHIAYTTPETLRLIRENVHRSPMYSGQIEAIGPRYCPSIEDKVVKFPDKDRHQFFLEPEGLNTHEVYVNGMSTSLPMEVQYEIVRSIPGLENAEMLRPGYAIEYDAIDPTELDRSLRVKKFEGLYLAGQINGTSGYEEAACQGIMAGINAALSVRDDAPFTLNRTEAYTGILIDDLISKGTNEPYRMFTSRAEFRLHLRIDNADRRLTPYGRRLGLIHDEAWADYEAKQARAVTLEKLLATRKIKDVTPLAPALAQAGITDAASLAGQTYAQLLKRPEMSIEALWTVIRAEVAEGEAASLFAPWFTNAEEASQPLPAFVRNELKSVETEIKYAGYLDQQRKSMEKLKKAETRVIPEWFDYASVSGLSREMQEKLVRVRPQTIGQASRIPGVTPAALSLINVYIEIQGKRLAKGGHPVQV
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYSY_STRPB
Sequence: MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFAEYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRTIGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVRRVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMFAKHFGWKIGKFFYFVNNLHIYDNQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPS52_CANLF
Sequence: MAAAATMAAAARELLLRAGTSDMEEEEGPLGGGPGLQEPLPLGELDISSDEFILDEVDVHIQANLEDELVKEALKTGVDLRHYSKQVELELQQIEQKSIRDYIQESENIASLHNQITACDAVLERMEQMLGAFQSDLSSISSEIRTLQEQSGAMNIRLRNRQAVRGKLGELVDGLIVPSALIMAILEAPVTEPRFLEQLQELDAKAAAVREQEARGTAACADVRGILDRLRVKAVTKIREFILQKIYSFRKPMTNYQIPQTALLKYRFFYQFLLGNERATAKEIRDEYVETLSKIYLSYYRSYLGRLMKVQYEEVAEKDDLMGVEDTAKKGFFSKPSLRSRNTIFTLGTRGSVISPTELEAPILVPHTAQRGEQRYPFEALFRSQHYALLDNSCREYLFICEFFVVSGSAAHDLFHAVMGRTLGMTLKHLESYLTDCYDAIAVFLCIHIVLRFRNIAAKRDVPALDRYWEQVLALLWPRFELILEMNVQSVRSTDPQRLGGLDTRPHYITRRYAEFSSALVSINQTVPNERTMQLLGQLQVEVENFVLRVAAEFSSRKEQLVFLINNYDMMLGVLMERAADDSKEVESFQQLLNARTQEFIEELLSPPFGGLVAFVKEAEALIERGQAERLRGEEARVTQLIRGFGSSWKSSVESLSQDVMRSFTNFRNGTSIIQGALTQLIQLYHRFHRVLSQPQLRALPARAELINIHHLMVELKKHKPNF
What is the function of this protein?
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).  The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD.  Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 52 homolog.
What is the protein family that this protein belongs to?
Belongs to the VPS52 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome. Note=Localizes to the trans-Golgi network as part of the GARP complex, while it localizes to recycling endosomes as part of the EARP complex.
Protein: Y1544_PORGI
Sequence: MLILLSCAKTIGIPKRLPSHLTTTSPIFDEQTTKIALAASSCDIKELSRLLRINRKLAEENHRRWQHFFEDDSPTAPAALAYTGMVFKKLAPANFNADDWLYASEHLLITSFLYGLLRPSDMIRPYRMEGFAHLGAPVEDEVFNFWRPYLTDFLIEKVREKGGELCFLASEEMKMLFDWKRVEQAVRVVTPLFKVPQPDGGLKQIVIYTKMARGLMTAHLLTRRCRHVEEMQLFSPEGFIFRPELSDESNYLFVME
What are the official names of this protein?
UPF0246 protein PG_1544.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SECY_ARCFU
Sequence: MDSVIRALQPYFERIPSVERPKGHVHFREKFGWTAAILLLYFILSNVPVFGLSPESIDIFAAYRALFAGSTGSIIALGIGPIVTASIILQLLVGAGIIKLDLTNPEDRAAYQDFQRFLVFVMIAVEAIPQIAGGLLKPDLNLAAQLGVSPGIISFLIFIQLFIGGVLIVYMDEVVSKWGIGSGVSLFILAGIAQSIVVGLFNWVIPPNSAMPAGIIPRWIWIAQNYPLDQLFTGSGLAFLLIQGGILALITTAAIILLVVFFEGTRVEIPLAHAVARGARGRFPIKLIYASVLPMIFVRALQANVVALGQVLHARGVTIFGEFVNGKAVSGLMFFLQPVSSPYDWIPSLVKSQGAAFAAIPDWMIYLHLLIDALILVVGGIIFAWFWVETSGMDARTVASQIAKSGMQVPGFRKSPQVLERVLSRYIPKVTILGGAIIGILTLVANMLGTIGNVSGTGLLLAVSIAYRFYEDLAKEQLTEMHPLIRRMLGEEA
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY, Protein transport protein SEC61 subunit alpha homolog.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y921_BACHK
Sequence: MIVTTTSGIQGKEIIEYIDIVNGEAIMGANIVRDLFASVRDVVGGRAGSYESKLKEARDIAMDEMKELAKQKGANAIVGVDVDYEVVRDGMLMVAVSGTAVRI
What are the official names of this protein?
UPF0145 protein BT9727_0921.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: TCEA1_TULGE
Sequence: MSVASFFSSLPARPFGYKDGRGRTGMVPTTDIGRRMVKPPVLACRPIESNTYHGSVTSVFLTKSSRSPSPSLSPTPTALDDEIVLDLKPFLIIYKSGRIERFLGTTVIPACPEVATKDVVIDPATGVSVRLYLPNVVDLPSKKLPVLVYFHGGGFVIENTGSPNYHNYLTLLAAKAGVLIVSINYRLAPEYPLPASYDDCMAGFNWVVSHSAGPALEPWLAQHGDFSQILLSGDSAGGNVTHYVAMRADAGVIEGVAIVHPYFLGSEPVGNEINDPANIEFHDKLWRLAAPDTEGLDDPLINPVAPGAPSLAGLKCKRAVVFVAGNDFLVERGRMYYEALVKSGWRGEAELVQHEGVGHVFHLSDYSGDISVAMMTKLIAFLKGE
What is the function of this protein?
Lactone-forming carboxylesterases, specifically catalyzing intramolecular transesterification, but not hydrolysis.  Involved in the biosynthesis of tulipalins, defensive chemicals that show antimicrobial activities against a broad range of strains of bacteria and fungi.  Substrates are 6-tuliposide A > 6-tuliposide B.
What are the official names of this protein?
Tuliposide A-converting enzyme 1, chloroplastic, TgTCEA1.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: TNFB_RAT
Sequence: MTPLGRLHLLRVLSTPPVFLLGLLLALPLGAQGLSGVRFSASRTAHQPPQKHLTHGLLKPAAHLVGYPSKQNSLLWRANTDRAFLRHGFSLNNNSLLIPTSGLYFVYSQVVFSGESCSPRAIPTPIYLAHEVQLFSSQYPFHVPLLSAQKSVYPGLQGPWVRSMYQGAVFLLSKGDQLSTHTDGISHLHFSPSTVFFGAFAL
What is the function of this protein?
Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (By similarity).  In its heterotrimeric form with LTB binds to TNFRSF3/LTBR.  Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
What are the official names of this protein?
Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1.
What is the protein family that this protein belongs to?
Belongs to the tumor necrosis factor family.
What are the subcellular locations of this protein?
Secreted. Membrane. Note=The homotrimer is secreted. The heterotrimer is membrane- associated.
Protein: Y390_STRS2
Sequence: MKNNSIKTVVATGIGAALFVVIGHLINIPTFVPNTSIQLQYAVQSLLAVVFGPVVGFLVGFIGHTLKDSLTYGPWWSWILASGVFGLVVGLTKKRLRIQEGIFEGKDILFFNLVQIAANVLAWGVIAPVLDILIYSEAANKVFAQGLVAGIANSITIAIAGTLLLVVYAKSQTKTGSLSKD
What are the official names of this protein?
UPF0397 protein SSU98_0390.
What is the protein family that this protein belongs to?
Belongs to the UPF0397 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CSW_DROVI
Sequence: WFHGNLSGKEAEKLILERGKNGSFLVRESQSKPGDFVLSVRTDDKVTHVMIRWQDKKYDVGGGESFATLSELIEHYKRHPMVETCGTVVHLRQPFNATRITAAGINARVEQLVKGGFWEEFESLQQDSRDTFSRHEGYKDENRLKNRYHDHTRVKLQDVERSAPGAEYINANYIRLPTDGDLYNMSSSSESLNSTVAACPACTAAQTQRNCPNCHLLNKTCVKCAVKSATLPTNCATCNRKSDSLSKHKRSESMSASANASAAGTGPGTPTAAGNTSAAAALNGCLAVLLKKHCGDASPPPSTTSSCSGPLTGSLLNGEGNQFKTYIATQGCLANTKTDFWNMIWQENTRVIVMTTKEIERGKTKCERYWPDEGQCKQFGHAKVHCIKENSTNDYTLREFLFSWRDKPERRIYHYHFQVWPDHGVPADPGCVLNFLQDVNTKQSSLAQAGEKPGPICVHCSAGIGRTGTFIVIDMILDQIVRNGLDTEIDIQRTIQMVRSQRSGMVQTEAQYKFVYYAVQHYIQTLIARKRAEEQSLQVGREYTNIKYTGEIGNDSQRSPLPPAISNLSLVSCKSAVAEPLTAAAAAAAVAANAGNKHAAKLQPPLPPLGASNNNNSSGNSGSYCNSSSSTSTAQHNGVVSSSNNCSSGSGSANSSNANGNGNILGNGSNMRKSNFYSDSLAALKLQQQQLHDAATAAAAAALASAAAPAATTTAASASAAAAAAAAAKYKNIPKDMNSLRQPHAAYVAAAPALPPPPTPPRKT
What is the function of this protein?
Required in all receptor tyrosine kinase signaling pathways.  Functions downstream of the receptor tyrosine kinase torso, acting in concert with D-Raf via tailless.  Also functions downstream of Egfr (epidermal growth factor receptor) and btl (fibroblast growth factor receptor).  The SH2 domain suggests that csw effects its role by mediating heteromeric protein interactions.  Maternally required for normal determination of cell fates at the termini of the embryo.  Required for cell fate specification of the ventral ectoderm, in the developing embryonic CNS and for embryonic tracheal cell migration.  Functions during imaginal development for proper formation of adult structures such as eyes, aristae, L5 wing vein and the tarsal claw (By similarity).
What are the official names of this protein?
Tyrosine-protein phosphatase corkscrew.
What is the protein family that this protein belongs to?
Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 143BA_XENLA
Sequence: MDKSELVQKAKLSEQAERYDDMAASMKAVTELGAELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGNDKRQQMAREYREKVETELQDICKDVLDLLDRFLVPNATPPESKVFYLKMKGDYYRYLSEVASGDSKQETVASSQQAYQEAFEISKSEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKSAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGEEADNVEGDN
What is the function of this protein?
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.  Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.  Binding generally results in the modulation of the activity of the binding partner (By similarity).
What are the official names of this protein?
14-3-3 protein beta/alpha-A.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROC_CHRVO
Sequence: MSGSSMGRLFTVTSFGESHGPGIGCVVDGCPPGLALSEADIQLELDRRKPGTSRHVTQRREPDTVEILSGVYEGKTTGTPIALLIRNTDQRSKDYGNIADTFRPGHADYCYWHKYGTRDPRGGGRSSARETAVRVAAGAIAKKWLNEKYGIVIRGHMTQIGEVAIPFKSWEHVGGNPFFSADPDIVPRLEEYMDSIRKSLDSIGARLRVVADNVPVGWGEPVFDRLDADIAYAMMSINAVKGVEIGAGFGCVTQKGSEHGDELTPRGFASNHAGGVLGGISTGQQIDVSIAIKPTSSIAQPRRSINKQGEAVTMETHGRHDPCVGIRATPIAEAMLALVLIDHALRHRAQCGDVRVETPRIAGHIG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: RUTC_ECOCB
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINETYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: RSMA_PROMH
Sequence: MNNRVHQGHFARKRFGQNFLTDSYIIESIVESIYPQPGEAVIEIGPGLGALTEPVGERMDKMTVVEIDRDLAARLEVHPTLKDKLTIIQQDAMTIDFAQLAKERQQPLRVFGNLPYNISTPLMFHLFSFADAISDMTFMLQKEVVNRLVASHGSKTYGRLSVMAQYHCQVIPIIEVPPSSFKPAPKVDSAVVRLIPYKEKPYPVTDIAMLSRITSQAFNQRRKTLRNSLGGLLTAEDMLALDIDPTARAENISVEQYCKVANWLSSQQQHAE
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: END4_SHIBS
Sequence: MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEHLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: SCAF_BPAR1
Sequence: MLKEQLIAEAQKIDASVALDSIFESVNISPEAKETFGTVFEATVKQHAVKLAESHIAKIAEKAEEEVEKNKEEAEEKAEKKIAEQASKFLDHLAKEWLTENKLAVDKGIKAELFESMLGGLKELFVEHNVVVPEESVDVVAEMEEELQEHKEESARLFEELNKRDAYINYVQREVALSESTKDLTESQKEKVSALVEGIDYSDAFSSKLSAIVEMVKKSNKDESTITESINTPDTEEAGLNFVTEAVEDKSAQGAEDIVSVYAKVASRF
What is the function of this protein?
Cleavage product of Gp22 that is incorporated into the mature phage head.
What are the official names of this protein?
Capsid assembly scaffolding protein, Gene product 22, gp22, Head morphogenesis protein, Major prohead-scaffolding core protein Gp22, Scaffold protein.
What is the protein family that this protein belongs to?
Belongs to the T4likevirus capsid assembly scaffolding protein family.
What are the subcellular locations of this protein?
[Internal peptide VII]: Virion.
Protein: YME2_ASPNC
Sequence: MMRIPYRAVVPRATLLHARFSRPPAVPSLTKAFIVSRRTSSHASFIETGHIDVKDDEGLVFVNNIFPSKLQWLLQGPLSGNKTYEEALKRINRPHLAASDPLHIIRRVFPQSLNVDIREVIPRFREGGAFVKYVRKDGVRDNDIVTAVQHHLEHNPIRPWFNPFQQVKVAHVHGRPWIEDLYRIPSQRLRVEFLPGSVDGAATELTTETLYSFFRRYGKLRDIERQPTDSKIAPRYAFVSFTRQKYAVMAKNCMHGFTIPEEEGGGKSGTRIKIKYERKIKFSVIKDWILNHPRIVIPAIAALIAAITVTIFDPIRTFFIEMKIKATLQTEENSVLQWIRNQANKANIIYFGRQRTDPRRLTAIWEDRQGDIKQLQSWLMENAETFIVIHGPRGTGKRELVLDRALENYKYKVVIDCKQIQDAKGDTAKIARAASQVGYRPVFSWMNSMSSFIDLAAQGMIGTKAGFSETLDAQLSKIWQNTATALKRVALSNRKKDDKEAHLSDEEYLEAHPEQRPVVVIDNFLHNATESSVVYDKITEWAAGLTTGNIAHVVFLTTDVSFSKPLSKALPNSVFRTISLGDCSLDVGRKFVLSHLEHGAKDGANSGQNMEEVGDLGTLDSCIEVLGGRVTDLEFMARRIESGETPRAAVNRIIEQSASEILKMFVFDPDIESKQWSHEQAWHLIKTLAHSQDGTLPYNQVLLSDLFKENGETTLRALEQAELIAISSVNGCPDAVKPGKPVYRAVFKRLTENKTLSSRLDLDIVKQLLSSENKSIGKYEQELQVLGSLPKQPRELSARIQWLLQKVASSQNKISQYEHESAILQKVLRREH
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: RL6_METFK
Sequence: MSRVAKNPVAIPAKVEVVLSSDNIAVSGPLGKLSLPLSGDVAIERDGDNLTFAAASESQHARAMSGTLRSLVFNMVTGVSQGFTRKLTLLGVGYKAQAQGANLNLDLGFSHPVSHKMPDGVTVQTPSPTEIVLTGADKQVVGQVAAQIRAYRAPEPYKGKGVRYADEVVIIKETKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: HIS82_NITOC
Sequence: MTKDRVAQWIRPEIQRLSAYRVADAADLIKLDAMENPYTWSPELIEAWLERLRQVSVNRYPDPQARSLKLRLRQYLALPEDMEMILGNGSDELIQMVLLAVAGPGRSVVAPEPTFVMYRQIAALLGLQYQGVALREDFSLDLPAMLQVIRERVPAVVFIAYPNNPTGNLFSAEELQAIIEASPGLVIVDEAYSVFAGETFMPRLEDYDHLLVMRTLSKIGLAGLRLGMLMGNPAWIKELEKVRLPYNINQLTQVSAEFALEQPGGLDEQARLICKARAQLQRALQQLPGIQVYPSDANFILFRTPPHQAEAIFTAIKERGVLIKNLSGQGGLLTDCLRVTVGTADENHAFLKALKAGRKN
What are the official names of this protein?
Histidinol-phosphate aminotransferase 2, Imidazole acetol-phosphate transaminase 2.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: CMOB_HELP2
Sequence: MLICNDKFNPKTLLEEIMALRPWRKGPFKISQIKIDSEWDSSIKWDLVKNATPLKDKIVADVGCNNGYYLFKMLEYKPKSLVGFDPGVLVKKQFEFLAPFFDKEKKIIYESLGVEDLHEKYPNAFDVIFCLGVLYHRKSPLEALKALYHALKIKGELVLDTLIIDSPLDIALCPKKTYAKMKNVYFIPSVSVLKGWCERVGFENFEILSVLKTTPKEQRKTDFILGQSLEDFLDKTDPSKTLEGYDAPLRGYFKMLKPSKR
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: RECR_NITOC
Sequence: MSLFGLSLGRLLEALRCLPGVGPKSAQRMAFHLLESDREGGRHLAQALLEALDKMTHCQTCRILSETDLCSLCADSRRDRGQLCVVEMPSDVQAIEQATSYSGRYFVLMGHLSPLDGVGPEALGMDLLAKRLDTDQIREVILATNLTVEGEATAYYISELAQTRGITTTRIAHGVPLGGELEFIDSNTLSHAFQSRRHL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.