PharMolix/UniProtQA huggingface dataset:
Protein: AROQ_CLOB6
Sequence: MNNILVINGPNLNLLGKREPDMYGNITLENINQKIKLHFKNEDLKIDFFQSNEEGKIIDKIIESQKKYNAIVINPAAYSHYSIAILDAMRSINIPAVEVHLSNIYKREEYRKKSVTAEASLGVISGFGYYGYIMAIEFILNNLVREK
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: CYSJ_VIBPA
Sequence: MSFQKNEYSHKNVSEDNNGQGGNPPIASPLNDQQFNSLQQTVSELSSQQLAWVSGYFWGLAQHQPSAAATPIAQAAAAVSAKPAGKLTIIFASQTGNAKGVAEALEQEAKAEGIAVELFDASDYKGKNLAKETHVIIVASTNGEGEAPDNAIELHEFLQSKKAPKLSNLQYGVIALGDSSYEFFCQTGKDFDTYLAKLGATSFIERIDCDVDYEAAAEEWRKNALGKVKETLSSGNEAEIVQLPVGQAAASHSQYNKQNPYTATLLTSQKITGRDSGKDVRHIEIDLDGSGLTYQPGDALGVWYENSSELASDILGKVGLSGVETVDVDGESLSIHSALVSKFEITTSNPQLVAKFAELSGSKKLQKLAEDKDKLREYSANTQIVDVFAEKKTKLTADELVGLLRRLTPRLYSIASSQAEVDEEVHLTVGLVEYDHNDEKRYGGASSFLAQRLEEGGDVKVFVEHNNNFKLPEDDTTPIIMVGPGTGIAPFRSFIQERENRDAEGKNWLFFGDRTFTQDFLYQVEWQKYLKSGVLSRLDVAFSRDQVEKVYVQHRILENAAQVWQWIQDGAYIYVCGDATRMAKDVHDALVIVAEQEGKMPRDDAEQFINDLRKAKRYQRDVY
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.  The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
What are the official names of this protein?
Sulfite reductase [NADPH] flavoprotein alpha-component, SiR-FP.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Protein: SUMT_BACSU
Sequence: MGKVYIVGAGPGDPDLLTIKALKAIEKADVILYDRLVNKEILQYAKEQADLIYCGKLPDFHTMKQETINRFLVKYAQKGKMVVRLKGGDPFVFGRGGEEAECLSENGIPFEIIPGITSGIAAAAYAGIPVTHRDAGSNVAFVTGHYKKEEDFEEKWKALATGIDTLVIYMGIKNVQQIERKLLENGRDGSTPAAFIHWGTTDKQKSVFCTVDTLSETVIKENITNPSLIVIGNVVNYHYKLEWFESELKKQDLSEAL
What is the function of this protein?
Catalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1.  It is a step in the biosynthesis of both cobalamin (vitamin B12) and siroheme.
What are the official names of this protein?
Uroporphyrinogen-III C-methyltransferase, Urogen III methylase, S-adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT, Uroporphyrinogen III methylase, UROM.
What is the protein family that this protein belongs to?
Belongs to the precorrin methyltransferase family.
Protein: YKHA_BACSU
Sequence: METPETRFCKESKVVKTSRVFPLDTNNHNTLFGGKLMSYIDDIASISAARHCRRETVTASMDSVDFLKPIGQKDSVCLESYVTWVGTSSMEVFVKVIKEHLMTGERELAATSFLTFVALDSNGKPVPVPRVVPETEEEIMLHNTAVQRANERKNRKRHSQALANALGTDKPW
What are the official names of this protein?
Uncharacterized acyl-CoA thioester hydrolase YkhA.
What is the protein family that this protein belongs to?
Belongs to the acyl coenzyme A hydrolase family.
Protein: PROB_BIFA0
Sequence: MQTPSQEEVRRAVAAARTVVVKVGSSSLTQPSGHLDVDKLNALVGAIAQVRMLGGNIVLVSSGAIAAGFGPLGFESRPTDVATQQATASVGQGLLMAQYEMAFGRYGIRVGQLLITAEDTMQPRQYRNARRTMAKLLELGVVPIVNENDALASNEIRFGDNDRLSALIANMVRADALILLTDVDALYTAPPSEPGSHRIGFVPNITELLDQVRVGGSESGVGTGGMVTKLEAARMAAVSGIPAVLTAARNAGPALMGDEVGTAFAPVKQRGSARRLWIKFAAHPRGVLVADSGAAKAVRGGRASLLAAGVLESRGDFAAGDPVWIDDEAGNHLARGLAGYDSEEIPNMLGRNTAQLRRLLGEEYAHPLVHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGS1_ARATH
Sequence: MASGCALHGGCPSDYVAVAISVICFFVLLSRSVLPCLIHKAPRTNSSSFWIPVIQVISSFNLLFSIMMSVNLLRFRTKHWWRYCYLWAVWIEGPLGFGLLMSCRITQAFQLYFIFVKKRLPPVKSYIFLPLVLLPWIFGAAIIHATKPLNDKCHMGLQWTFPVAGLHALYVLALIAFTRAVRHVEFRFDELRDLWKGILVSATSIVIWVTAFVLNEIHEEISWLQVASRFVLLVTGGILVVVFFSISSNQPLLSQISLKKRQNFEFQRMGQALGIPDSGLLFRKEEFRPVDPNEPLDKLLLNKRFRHSFMEFADSCYAGETLHFFEEVYEHGKIPEDDSIRRIYMARHIMEKFIVAGAEMELNLSHKTRQEILTTQDLTHTDLFKNALNEVMQLIKMNLVRDYWSSIYFIKFKEEESCHEAMHKEGYSFSSPRLSSVQGSDDPFYQEHMSKSSRCSSPG
What is the function of this protein?
Glucose-regulated GTPase-accelerating protein (GAP) for the GTP-bound self-activating heterotrimeric G alpha protein GPA1.  Cooperates with G beta-gamma dimers to maintain an unactivated but fully functional pool of GPA1.  Phosphorylation-dependent endocytosis of RGS1 physically uncouples the two proteins, resulting in signal activation.  Free AGB1 is essential, but not sufficient, for RGS1 endocytosis.  Modulates cell proliferation, abscisic acid (ABA) and drought stress signal transduction by acting in a hexokinase-independent glucose-signaling pathway (PubMed:26528314).  Involved in the shapes of leaves, the development of floral buds, the elongation of stems, siliques, and hypocotyls, the time of flowering and the regulation of guard-cell K(+) and anion channels.  Important for the kinetics of voltage activation of inward K(+) current but not for the current amplitude.
What are the official names of this protein?
Regulator of G-protein signaling 1, AtRGS1.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=accumulates at the nascent cell plate during cytokinesis.
Protein: CODY_STAEQ
Sequence: MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPREYTEELMNVKQTESNIDIDNELTVFPPENREVFLNSRTTIFPILGGGERLGTLVLGRVQDDFNENDLVLGEYAATVIGMEILREKHNEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKDKFLDELEKK
What is the function of this protein?
DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability.  During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion.
What are the official names of this protein?
Global transcriptional regulator CodY.
What is the protein family that this protein belongs to?
Belongs to the CodY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1727_PSEAE
Sequence: MLISSYNQVLVAFSLIVAILASYTALDMAGRVTLAKGREALSWLIGGAFAMGFGIWSMHFVGMLAFSLPIPLGYDLGLTLLSLLLAVGSSAFALWLVCQAELPWQRLALGALLMGSGIAAMHYTGMAALLMMPGIVYDPLWLGLSILIAVIASGAALWIAFRLRHGSRRIVLVRAGAALVMGCAIVGMHYTGMAAAQFPLGSFCGAAGRGIDNGWLAVLVIVITLAVIAIALIVSVLDSRLEARTSVLATSLARANRELIQLALHDNLTKLPNRMLLDDRLEQAIQQAIRDDRRFAVLFMDLDGFKAVNDAYGHHLGDLLLIEVAERIRANVRAQDTIARLGGDEFVLLIEAREPADAATLAEKLVKRISQPYQISRHEVRISASIGIALYPGDGQTRHELMINADAAMYHAKDQGRNGYCFFESSMNANAQEQLQLLHDLRQALERRQLVLHYQPKVLAPNGPMIGVEALLRWEHPQHGLITPGQFLPLAEKTGLIVQIGEWVLDEACRQMRLWLDGGHADWNIAVNLSALQFAHAGLVDSVRNALLRHSLEPSHLILEVTESTAMRDADASLVILEQLSAMGVGISIDDFGTGYSSLLYLKRLPASELKIDRGFINELAHDSDDAAIVSAIVALGRTLNLKIVAEGVETEAQQEFLTRLGCNSLQGFLLGRPMPAEQLLASVA
What are the official names of this protein?
Uncharacterized signaling protein PA1727.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1179_ACAM1
Sequence: MKIWVDADACPNAIKEILYRAARRVKIHLTLVANQYINPPASDYIDAVQVPAGFDGADNHIVEHLQAGDLVITADIPLAAAVIEKLGHALNPRGELYTQNNMRERLSMRNFMEEMREGGLVTGGPPALNQRDRQLFANQLDRFLAKHHQPPA
What are the official names of this protein?
UPF0178 protein AM1_1179.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: AROQ_PSEU2
Sequence: MATILVLHGPNLNLLGTREPGVYGTITLPQINQDLEQRARDAGHHLMYLQSNAEYELIDRIHAARGEGVDFILINPAAFTHTSVAIRDALMGVSIPFIEVHLSNVHKREPFRHHSYFSDVAVGVICGLGASGYRLALEAALEQLAASAKP
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RS8_RHORT
Sequence: MALSDPIGDMLTRIRNGQRARKSSVMAPASTMRANVLDVLIREGYIRGYEKVDVRKGIAELRVELKYHEGEPVIREIARVSTPGRRVYSKIKDLPKVYNGLGISILSTPRGVMSDHEARQANVGGEVLCRVF
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PDE11_MOUSE
Sequence: MAASRLDFGEVETFLDRHPELFEDYLMRKGKQELVDKWLQRHTSGQGASSLRPALAGASSLAQSNAKGSPGIGGGAGPQGSAHSHPTPGGGESAGVPLSPSWASGSRGDGSLQRRASQKELRKSFARSKAIHVNRTYDEQVTSRAQEPLSSVRRRALLRKASSLPPTTAHILSALLESRVNLPQYPPTAIDYKCHLKKHNERQFFLELVKDISNDLDLTSLSYKILIFVCLMVDADRCSLFLVEGAAAGKKTLVSKFFDVHAGTPLLPCSSTENSNEVQVPWGKGIIGYVGEHGETVNIPDAYQDRRFNDEIDKLTGYKTKSLLCMPIRNSDGEIIGVAQAINKVPEGAPFTEDDEKVMQMYLPFCGIAISNAQLFAASRKEYERSRALLEVVNDLFEEQTDLEKIVKKIMHRAQTLLKCERCSVLLLEDIESPVVKFTKSFELMSPKCSADAENSFKESVEKSSYSDWLINNSIAELVASTGLPVNVSDAYQDPRFDAEADQISGFHIRSVLCVPIWNSNHQIIGVAQVLNRLDGKPFDDADQRLFEAFVIFCGLGINNTIMYDQVKKSWAKQSVALDVLSYHATCSKAEVDKFKAANIPLVSELAIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQEILTEVEILAVIVGCLCHDLDHRGTNNAFQAKSDSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTEFFELVRKGDYDWSITSHRDVFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERSELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQALVKVNAKLKPMLDSVAANRRKWEELHQKRLQVSAASPDPASPMVAGEDRL
What is the function of this protein?
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP (PubMed:15800654).  Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (By similarity).
What are the official names of this protein?
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, cAMP and cGMP phosphodiesterase 11A.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CIDA_STAA9
Sequence: MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFLFYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIGTCIVALSSGYIAEKMSVKHKHRKGVDAYE
What is the function of this protein?
Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation.  Inhibited by the antiholin-like proteins LrgAB.  In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.  When a cell is stressed by the addition of antibiotics or by other factors in the environment, the CidAB proteins possibly oligomerize within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability.  These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and/or regulating their activity by a possible change in the cell wall pH that results from loss of membrane potential.
What are the official names of this protein?
Holin-like protein CidA.
What is the protein family that this protein belongs to?
Belongs to the CidA/LrgA family. CidA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SIA8C_PANTR
Sequence: MRNCKMARVASVLGLVMLSVALLNLSLISYVSLKKENIFATPKYASPGAPRMYMFHAGYRSQFALKFLDPSFVPITNSLTQELQEKPSKWTFNRTAFLHQRQEILQHVDVIKNFSLTKNSVRIGQLMHYDYSSHKYVFSISNNFRSLLPDVSPIMNKHYNICAVVGNSGILTGSQCGQEIDKSDFVFRCNFAPTEAFQRDVGRKTNLTTFNPSILEKYYNNLLTIQDRNNFFLSLKKLDGAILWIPAFFFHTSATVTRTLVDFFVEHRGQLKVQLAWPGNIMQHVNRYWKNKHLSPKRLSTGILMYTLASAICEEIHLYGFWPFGFDPNTREDLPYHYYDKKGTKFTTKWQESHQLPAEFQLLYRMHGEGLTKLTLSHCA
What is the function of this protein?
Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages.  Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids.  Displays preference for substrates with alpha-2,3-linked terminal sialic acid.  It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.
What are the official names of this protein?
Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase, Alpha-2,8-sialyltransferase 8C, Alpha-2,8-sialyltransferase III, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3, Sialyltransferase 8C, SIAT8-C, Sialyltransferase St8Sia III, ST8SiaIII.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 29 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: NYX_HUMAN
Sequence: MKGRGMLVLLLHAVVLGLPSAWAVGACARACPAACACSTVERGCSVRCDRAGLLRVPAELPCEAVSIDLDRNGLRFLGERAFGTLPSLRRLSLRHNNLSFITPGAFKGLPRLAELRLAHNGDLRYLHARTFAALSRLRRLDLAACRLFSVPERLLAELPALRELAAFDNLFRRVPGALRGLANLTHAHLERGRIEAVASSSLQGLRRLRSLSLQANRVRAVHAGAFGDCGVLEHLLLNDNLLAELPADAFRGLRRLRTLNLGGNALDRVARAWFADLAELELLYLDRNSIAFVEEGAFQNLSGLLALHLNGNRLTVLAWVAFQPGFFLGRLFLFRNPWCCDCRLEWLRDWMEGSGRVTDVPCASPGSVAGLDLSQVTFGRSSDGLCVDPEELNLTTSSPGPSPEPAATTVSRFSSLLSKLLAPRVPVEEAANTTGGLANASLSDSLSSRGVGGAGRQPWFLLASCLLPSVAQHVVFGLQMD
What are the official names of this protein?
Nyctalopin.
What is the protein family that this protein belongs to?
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: CYDE_METJA
Sequence: MVSIMNKNELITEILKNEVVKALGCTEVGLIGYTVAKAKPEDLYSIKEIKLILDKGTFKNAFSVGVPNTNKFGILPAVVGGLLGREENKLEVFKDIKYDEKLEEFIENKLKIEVIDSDVYCKVIIKANKVYEAETKGSHSGKSLSDDLKNAYKSLTLKDFIDYIEDIPEEVIKIIKETIETNKNLSTPEVPEDFISLDLKDEILNHMLKKTVSAVYNRMIGINKPAMAIAGSGNMGLTATLPIIAYDEIKGHDEEKLTKSITLSALTTIYSAYHSSYISAMCGCVNRGGIGAVSGLSYYIFGFDRIEESIKSFTANLPGIVCDGGKIGCALKIASGVFAIYLSLFSKVPYTNGIVGKDFKECIENIGKIGKAMKPVDDEIIEILKNKK
What is the function of this protein?
Catalyzes the cleavage of L-cysteine to form 2-aminoprop-2-enoate and sulfide.  The former then spontaneously hydrolyzes to pyruvate and NH(3).  May be responsible for the production of sulfide required for the biosynthesis of iron-sulfur centers in this archaea.  Is very specific for L-cysteine, with no activity being detected with D-cysteine, L-homocysteine, 3-mercaptopropionate (cysteine without the amino group), cysteamine (cysteine without the carboxylate), or mercaptolactate (the hydroxyl analog of cysteine).
What are the official names of this protein?
L-cysteine desulfidase, L-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the L-cysteine desulfidase family.
Protein: RPRML_HUMAN
Sequence: MNATFLNHSGLEEVDGVGGGAGAALGNRTHGLGTWLGCCPGGAPLAASDGVPAGLAPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLVQERRPSKDVGAAILGLY
What are the official names of this protein?
Reprimo-like protein.
What is the protein family that this protein belongs to?
Belongs to the reprimo family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MURB_METC4
Sequence: MTAHSLIDAIRAAAPDLRGRLLENQSLADLTWFRVGGPAQVLFSPADEADLSAFLAALDPSVPVTVIGLGSNLIVRDGGIPGVTIRLGGKAFGSVEIDGETIRSGTAVPDMRLAKAAAEASLDGLAFFRGIPGSVGGALRMNAGAHGGETTDVLVEVRGIDRKGEVHRFTHAEMGFRYRHSSAPDDVIFTGATFRGRPGDREAIEAEMERVTAAREAAQPIRERTGGSTFKNPEGGKAWQLIDAAGCRGLIRGGAQVSEMHCNFLINRGGATAADIEGLGEEVRRRVREHSGFELHWEIKRIGVEASPA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEP_ASPNC
Sequence: MHGLRLVCSIGTLPLVILAYPAASLHTTSAAVDLDSLRLTSNSEYVNSVHVDTNRSVAVSAEEHYTDTAARLVQNIVPGASFRLIDDHFVGDNGVAHVYFRQTLHGIDIDNADFNVNIGKDGLVLSFGHSFFTGALPSSHLDNTNVLSPEAALRGARDAIQLPLTIDNVSTEAAEGRNEYIFREAVGAVSDPKAKLVYLVKPEGTLALTWRIETDMYEHWLLTYIDAETTTVHGVVDYVADATYQVYPWGTNDPAEGHRTIVTDPWDLSASAYTWISDGRDNYTTTRGNNAIAHWNPTGGGSYLYNLRPSDPNLNFQWPYSPNMSPPRSYINASIVQLFYTANAYHDLLYTLGFTESAGNFQWNNSAHGGRDKDYVILNAQDGSGFSNANFATPPDGIPGRMRMYIWIESTPSRDGSFDAGIVIHEYTHGVSNRLTGGSHNAGCLSALESGGMGEGWGDFMATAIRIKPNDTRTTSYTMGAWADNDKCGVRDYPYSTSFTENPLNYTSVNTMNGVHAIGTVWATMLYEVLWNLIDKYGKNDGSRPVFRNGVPTDGKYLMMKLVVDGMALQPCNPNFVQARDAILDADIVLTGGKNRCEIWRGFAKRGLGQGAAHSSLNWMRRGSTLLPTGC
What is the function of this protein?
Secreted metalloproteinase that allows assimilation of proteinaceous substrates.
What are the official names of this protein?
Extracellular metalloproteinase mep, Elastinolytic metalloproteinase mep, Fungalysin mep.
What is the protein family that this protein belongs to?
Belongs to the peptidase M36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACADM_RAT
Sequence: MAAALRRGYKVLRSVSHFECRAQHTKPSLKQEPGLGFSFELTEQQKEFQTIARKFAREEIIPVAPDYDKSGEYPFPLIKRAWELGLINTHIPESCGGLGLGTFDACLITEELAYGCTGVQTAIEANSLGQMPVIIAGNDQQKKKYLGRMTEQPMMCAYCVTEPSAGSDVAGIKTKAEKKGDEYVINGQKMWITNGGKANWYFVLTRSNPDPKVPASKAFTGFIVEADTPGIHIGKKELNMGQRCSDTRGITFEDVRVPKENVLIGEGAGFKIAMGAFDRTRPTVAAGAVGLAQRALDEATKYALDRKTFGKLLVEHQGVSFLLAEMAMKVELARLSYQRAAWEVDSGRRNTYFASIAKAFAGDIANQLATDAVQIFGGYGFNTEYPVEKLMRDAKIYQIYEGTAQIQRLIIAREHIEKYKN
What is the function of this protein?
Medium-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation, an aerobic process breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats (PubMed:3968063).  The first step of fatty acid beta-oxidation consists in the removal of one hydrogen from C-2 and C-3 of the straight-chain fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA (PubMed:3968063).  Electron transfer flavoprotein (ETF) is the electron acceptor that transfers electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity).  Among the different mitochondrial acyl-CoA dehydrogenases, medium-chain specific acyl-CoA dehydrogenase acts specifically on acyl-CoAs with saturated 6 to 12 carbons long primary chains (PubMed:3968063).
What are the official names of this protein?
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, MCAD.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: BTUB_SHIF8
Sequence: MIKKASLLTACSVTAFSAWAQDTSPDTLVVTAIRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDGVRLNLAGVSGSADLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEISAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFLSKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAGVDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIYYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
What is the function of this protein?
Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space.  It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
What are the official names of this protein?
Vitamin B12 transporter BtuB, Cobalamin receptor, Outer membrane cobalamin translocator.
What is the protein family that this protein belongs to?
Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: EFG_METEP
Sequence: MPRTHAIEDYRNFGIMAHIDAGKTTTTERILYYTGKSHKIGEVHEGAATMDWMEQEQERGITITSAATTCFWRDKRLNIIDTPGHVDFTIEVERSLRVLDGAVCVLDGNQGVEPQTETVWRQADKYDVPRVVFVNKMDKIGADFFKCVADIIGRVAGKPVCLQLPIGAESSFKGVIDLIKMKAIVWSGEALGANFSEEEIPADLADQAVEYRTKMIEACVELDDDAMTAYLDGVEPDEETLRKLVRKAVQLRAFHPVLCGSAFKNKGVQPLLDAVVDYLPSPADRGEIKGLDFKTEEEVVRHPTDSDPFSMLAFKIMDDPHVGTITFCRVYSGKVESGANVINSSRDKKERVGRMLLMHANNREDVKEAFAGDIVALAGLKDTRTGDTLCDPKDAVILEKMEFPEPVIEIAVEPKSKADQEKLGIALSKLAAEDPSFRVSTDQESGQTILRGMGELHLDIKVDILRRTYKVDANIGQPQVAYREKLTRRQEIDYTHKKQTGGTGQFARVKFVVEPNEPGAGFAFESKIVGGAVPKEYIPGVEKGLNSVLGAGVLAGFPVVDVKVELIDGAYHDVDSSALAFEIASRAAFREALQKGGSVLLEPVMKVEVVSPEEYTGSVIGDLNSRRGQIQGQDMRGNANVINAMVPLANMFGYVNQLRSFSQGRANFTMQFDHYEEVPRGEADKVIAKYA
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_BURP1
Sequence: MTVKLTIDCMGGDHGPSVTVPAAVKFVRSHPDAHLMLVGIESAIRAQLKKCKALGEPALSVVPATEVVAMDDPVEVALRKKKDSSMRVALNHVKEGAAQACISAGNTGALMAVSRYVLKTLPGIERPAIAFALPNPTGYTMMLDLGANVDCEPQHLLQFAEMGHALVAALEGKERPTIGLLNIGEEVIKGNETIKRAGELLRASTLNFRGNVEGNDIYKGTVDVIVCDGFVGNVALKTSEGLAQMLADIIKEEFSRSLLSKLMAILALPVLLRFKKRVDHRQYNGAALLGLRSLVIKSHGSADAYAFEWAIKRGYDAVKNGVLERLSRAMAENAAPLGESGRDANGAGQASPSAGQPAEPSAALSSKT
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: ATPE_LACSA
Sequence: MTLNLCVLTPNRIVWDSEVKEIILSTNSGQIGVLPNHAPIATSVDIGILRIRLNDQWLTMALMGGFARIGNNEITVLVNDAEKSGDIDPQEAQQTLEIAEAALRKAEGKRQTIEANLALRRARTRVEAINAIS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.