PharMolix/UniProtQA huggingface dataset:
Protein: COBQ_COREF
Sequence: MAAGPAFLIAGTTSDAGKSVITAGLCRAFARAGLRVAPFKAQNMSNNSAVTSDGGEIGRAQALQALACGLEPSVEFNPILLKPGPDNRARLVIRGREQGDVGAGDYIRHRHDLRGIAAAQLESLRERFDIVVCEGAGSPAEINLRATDVANFGLAQAAQLAVYIVGDIDRGGVLAHLFGTHAIISDEDRALIRGFVINKFRGHQELLEPGLVQLEELTGVETKAVIPFIDDIWIDAEDSLQSPVGRMVGPGGRHPLGTQRLSVAAIRLPRMLGVTDVEALAVEPGVTVTWVDDVDAVWDSDLVIIPGTTATVADLAWLRHRGLDRALGERATRGMPILGIGGGYQMMATTITDEGDSPSSVAGLALFDVHIALTPHNIMVNHGDGSYEVHHGQVRHHGEQTWIEGEGARREALFGTHRHGYLQDDPARRRFLTEVATHAGKPGFLVSPDTSFHGVRLQQLDRIADVLEEHWDLDQLLDEVSRPANAANTPETR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: MTNB_XANC5
Sequence: MNATTAPLPYSTTRLHELAHLLIANIRELAHAGWTPATSSNFSHRLDEQHAAITVSGRDKGRLVEENIMVVDFDGLAVGRPLRPSAETLLHTQLYRRFPEIGCVLHTHSPVQTIASRLYAGSGVIRLEGYELLKAFDGNTTHETAVEVPVFANTQDMQVLAAQVDALLDKQSMWGYLIEGHGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRGTR
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
Protein: DBP10_CANGA
Sequence: MVKNLKRKERDEHESDSDEEIDIAGNLVADGSDSESDDSSDGSDEEVQDVIEYSSDEEEPAKPAKAVKKKVEDKSFPSLELSDDEDEKKKVDNDDDDVNAYFSVNTDAKSKHKKGSFASFGLSKLILVNISKRGFRQPTPIQRKTIPLILQNRDIVGMARTGSGKTAAFVLPMIEKLKTHSSKIGARAIILSPSRELAMQTHSVFKEFSRGTHLRSVLLTGGDSLEDQFGMMMTNPDVIIATPGRFLHLKVEMNLDLKSVEYAVFDEADRLFEMGFQEQLNELLAALPSSRQTLLFSATLPTSLVDFAKAGLVNPVLVRLDAESKISDNLEMLFLSTKNDEREANLLYILQEVIKLPLATPEQIKQLNDNKADDSDESAEEDEDKKRRKRKSFNRKAMPKANELPSEKATVVFVPTRHHVEYLSNLLKDCGYLVSYIYGALDQHARKSQLYNFRIGLTSILVVTDVAARGVDIPMLANVVNYSLPASSKIFIHRVGRTARAGNRGWAYSIVSENELPYLLDLELFLGRKILLTPMYEALERLSKEKWVAEGNDETLFQSPKISYTSRMVLGSCPRLDIEALSELYNNLMKSNFDLDMAKKTALKAEKLYFRTRTSASPESLKRSKEIISSGWDEQNVLFGKNLEKEKNAFLEKLQNRRNKETVFEFTRNPEDEMANLMHRRRRAIAPIQRKAKERKELLEKERMAGLTHALEDEILKGDDAEVGYTVTEDTLKAFEDADTILAEQENASKKKKKTFRDPNFFLSHYAPANEIQDKQLELSGGFINEAAQSAYDLNSDDKVQVHKQTATVKWDKKRKKYVNMNGIDNKKYIIGESGQKIAASFRSGKFDEWSKARKLAPLKTGANESSIPSNLLVDPTRGPGKSGSKLPNGKFKHKLEKAPRLPDKKRDDYHKQKKKVESALERGIAVKGYNNAPAFKSELKSVAQIRKDRKTKENRHAKNARPSKKRKF
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: IL33_PONAB
Sequence: MKPKMKYSTNKISTAKWKNTASKALCFKLGKSQQKAKEACHVYFMKLRSGLMIKKEACYFRRETTKRPSLKTDRKHKRHLVLAACQQQSTVESFAFGISGVQKYTRALHDSSITGISPITEYLASLSTYNDQSVTFALEDESYEIYVEDLKKDEKKDKVLLSYYESQRPSSESGDGVDGKMLMVTLSPTKDFWLHANNKEHSVELHKCEKPLADQAFFVLHNRPSNCVSFECKTDPGVFIGVKDNHLALIEVDSSENLGTENILFKLSET
What is the function of this protein?
In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets.  This form is rapidely lost upon angiogenic or pro-inflammatory activation (By similarity).
What are the official names of this protein?
Interleukin-33, IL-33.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family. Highly divergent.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Secreted. Note=Associates with heterochromatin and mitotic chromosomes. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10; it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion.
Protein: CLP1_ASPCL
Sequence: MSLPGLELSQTSAEREFVSAPPTQISLSKGSEWRFEVAFGTAIRVKLLSGTAELFGTELAASQTYAFSGTKAAIYTWHGCTLEVGAGDTISTIDGLGSAGMNGGAVRGYGAGGCQSEYTAEETPMVEYANVHFALEAMRQEAKATGKDGPRVLILGPENAGKTSLAKILTAYATKVGRQPIVVNLDPAEGMLSVPGSLTATAFRTMMNVEEGWGSSPMSGPSAIPVKLPLVYFYPLQNPLEAGASVYRPIVSRLALSVTGRMAEDEDTRETGIIVDTPGILSQGKAGSLEVINHIVTEFAINTILVIGSERLYSTMMRSYDNKPTASASAAASDERITVVKLSKSGGCVDRDAAFMKAVRESQIRTYFFGNPIPSTASAALSASASSTTNVTLSPHAQQLDFDSLAVYNYTISLPDEDEDEYDPSQLGTGDTFIPGGSNEAERAEPQQAEDSSFTPSMPGLAGSSGEDATSAANSAVPLKKVPRPAPTVLANSLLAITHAAPSAPSSEIRDASIMGFLYVADVDSEKGKIRVLAPIGGRVPPRAIVWGKKWPGEVVGLVG
What is the function of this protein?
Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
What are the official names of this protein?
mRNA cleavage and polyadenylation factor clp1.
What is the protein family that this protein belongs to?
Belongs to the Clp1 family. Clp1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: THO4B_ARATH
Sequence: MSGGLDMSLDDIIKSNRKPTGSRGRGGIGGGNNTGGRGGSGSNSGPSRRFANRVGARTAPYSRPIQQQQAHDAMWQNDVFATDASVAAAFGHHQTAVVGGGSSIETGTKLYISNLDYGVSNEDIKELFSEVGDLKRYGIHYDRSGRSKGTAEVVFSRRGDALAAVKRYNNVQLDGKLMKIEIVGTNLSAPALPILATAQIPFPTNGILGNFNENFNGNFNGNFNGNFRGRGRGGFMGRPRGGGFGGGNFRGGRGARGRGGRGSGGRGRDENVSAEDLDAELDKYHKEAMETS
What is the function of this protein?
Export adapter involved in nuclear export of spliced and unspliced mRNA.
What are the official names of this protein?
THO complex subunit 4B, ALYREF homolog 2, AtALY2.
What is the protein family that this protein belongs to?
Belongs to the ALYREF family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: PWAPL_MYTGA
Sequence: MNVYFILFLGVFAFIEVNCKSRKSKSLGTCPKLDVSTVCVVDYKFNCLFQKQCPSGYRCCTYGCNRRCAAVTVNKKHLGSCRNSSGKKGKRCKKDKSCKRHEKCCNKRCRRVRKKIAPVRTLSKNSSNSFSFLMKLISINR
What are the official names of this protein?
Perlwapin-like protein.
What are the subcellular locations of this protein?
Secreted.
Protein: RECA_KLEP3
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPVYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFFGELVDLGVKEKLIEKAGAWYSYNGDKIGQGKANAITWLKENPAAAKEIEKKVRELLLNNQDSTPDFAVDGNDAEETEQDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CVN4A_DANRE
Sequence: MEKRGDVILGVEDESGQPVSALSILSLLERVSTIIDGVQASQQRMEERQQQLEGSVSAVQSELLKLARDHGATATTVDKLLQKARRVSTHVKEVRSRVEKQNVRVKKVETTQDELLTRNKFRVVIYQGEKEVPSVAVTKTPKGAGLAELEVEPDEYDIPADLSSDEEYMVVEDAESSRGARLKQSGLKGIENIKAAFSKENMNKTREKTRENLSKTKESLSKTGQTLGTKFNTLGEKIVPPEQREKIKQSSERLKENIAKKAPTKESFKIKLKKERTVAEGQEGAEAEPAVTPPKGRKSSPDVTYTEVVTENKREGPVSEEGATRIHED
What is the function of this protein?
Induces rhoa activation and activates nppa transcription and myofibrillar organization through the rho/rock signaling pathway.
What are the official names of this protein?
Caveolae-associated protein 4a, Muscle-related coiled-coil protein a, Muscle-restricted coiled-coil protein.
What is the protein family that this protein belongs to?
Belongs to the CAVIN family.
What are the subcellular locations of this protein?
Cytoplasm, myofibril, sarcomere. Cytoplasm. Membrane, caveola. Note=Localizes in the caveolae in a caveolin-dependent manner.
Protein: ACPH_RABIT
Sequence: MERQVLLSEPEEAAALYRVLSRQPALSAACLGPDVTTQYGGRYRTVHTEWTQRDLERMENIRFCRQYLVFHDEDSVVFAGPAGSSVETRGELLSRESPSGTLKAVLRKAGGTGPGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPKAESFFQTKALDVSAGEDETARPKKPDQAVKGDQFVFYEDWGESMVSKSTPVLCVLDVESGNISVLEGVPENVSPGQAFWAPGDTGVVFVGWWHEPFRLGIRFCTNRRSALYYVDLTGGKYELLSDDSLAISSPRLSPDQCRIVYLRYPSLVPHHQCSQLCLYDWYTKVTSVVVDIVPRQLGENFSGIYCSLLPLGCWSADSQRVVFDSAQRSRQDLFVVDTQTGSVTSLTAGGSGGSWKLLTIDQDLMVAQFSTPSLPPSLKVGFLPPAGKEQSVSWVSLEEAEPIPDIHWGIRVLQPPPEQENAQYAGLDFEAILMQPGSPSDKTQVPMVVMPHGGPHSSFVTAWMLFPAMLCKMGFAVLLVNYRGSTGFGQDSILSLPGNVGQQDVKDVQFAVEQVLREERFDTGRVALMGGSHGGFLSCHLIGQYPETYGACVARNPVTNIASMMGSTDIPDCAKSCRCVVEAGFPYSNDCLPDLSVWADMLDKSPIKYIPQVKTPLLLMLGQEDRRVPFKQGIEYYRALKARSVPVRLLLYPKSTHALSEVEVESDSFMNAVLWLRTHLGT
What is the function of this protein?
This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus (By similarity).  It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser (By similarity).  Also, involved in the degradation of oxidized and glycated proteins (By similarity).
What are the official names of this protein?
Acylamino-acid-releasing enzyme, AARE, Acyl-peptide hydrolase, APH, Acylaminoacyl-peptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase S9C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PMM_CANAL
Sequence: MSFANKQDPKTLVLFDVDGTLTPARLTISEEMKKTLEKLREKVVIGFVGGSDLSKQVEQLGPNVLNDFDYCFSENGLTAYKLGKELASQSFINWIGNEKYNKLVKFILRYLSDIDLPIRRGTFIEFRNGMINVSPIGRNASTQERNDYEKFDKQHHIRETMVEALKKEFPDFGLTYSIGGQISFDVFPTGWDKTYCLQHVEDEHFENIHFFGDKSYKGGNDYEIYNDPRTIGHAVNSPDDTIRILNETFKLQ
What is the function of this protein?
Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
What are the official names of this protein?
Phosphomannomutase, PMM.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic PMM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_NEOSM
Sequence: MLDHLEIAGRNFSSRLIVGTGKYKNFDETVKAIEASGAEVVTVALKRVNITDNKRESLQDYLDPKKYTYLPNTAFCFTAGEAVRHLALAREIGGWNLVKVEVFSEKEFLYPDMRETLKAVKILAGEGFHVMPYCNDDPIMCKRLEESGAVAIMPLAAPIGSGLGIQNLFNLKVIVKQSSVPVIVDAGVGTPSDAVIAMEAGCDGVLINTSIAKARFPVQMAKAMKHAVRAGRLGYLAGRMLPQQFASPSSNSSGIV
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_FRASN
Sequence: MSLLAVGLNHRTAPTSLLELAAVSADDAPKVLHDLVGADHLSEAVLLSTCNRTEIYAEVETFHGGLADISDQLSRVCGVPLTDLASHLYVHHEARAVSHLFSVVCGLDSMLVGETQILGQVRAAFRLAQAAEVTSGTLANLFQTALRVGKRAHTETSIDAAGASIVSVGVRMAAFDLQARRPDMLVAPVASPGCDPGDAVEALLRPELTAPVEVAGPAPLAGARVLIIGAGAVGSLAAQTVRRAGAGDVVVANRTAARAARVADLHDARAVGLAEIAHEVGRADLVISSTGASGLVVGHDAVRASLAGRGARPLVFLDLALPRDIDPAVRELPGVTLIDIEALRVALDGAQVAHDVEAVRALVTTEVAGFLDRRRAERVAPTVVALRAHAAAVVRDELERLRTRLPDLDNREWDMVSGTVRRVVDKLLHAPTVRVQQLAEAPGGDSYAEALRELFDLPRDVPAIVSAPDLDLVERT
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: PVK22_CELBM
Sequence: GSSGLISVPRV
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2 type 2, PVK-2 type 2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: LADH_METMP
Sequence: MFIDGKWIIREDIDVFDPYTLENIEKITALDREETKNAIEVTEKHKEIMKNLSPSKRYKILMKVAEHLSSKKDFFAKTISIDVGKPIKQSKIEVDRTLTALKLSAFYAKELRGETINSENGLIFTKKEPLGVIGAITPFNFPLNLATHKIGPAIATGNSVVLHPSSKAPIVAIYLTKIIEHVLKQMDIPRGVFNLATGNGEIVGDEISKNDNVNMVSFTGSVEVGESISKNAKMKKVTLELGGNNPMIVLKDSDIKLAAKSAVKSKFLNAGQVCISVGQVLVEEEVVETFTKYVIEETKKLILGNPLDKNTDIGPLISPESALRIENLIKQSVSEGGELLIGGNRQNSLISPAVINIDEENILSKIETFGPILPILTVKDSEEAVNIANNSKYGLQAGLFTNNINNAMKIADELEYGGIMINSSPTFRKDNMPFGGVKKSGLGREGIKYTVEEMSETKTVVIHNI
What is the function of this protein?
Involved in F420 biosynthesis through the oxidation of lactaldehyde to lactate.
What are the official names of this protein?
Lactaldehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: IF3_STAA3
Sequence: MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3186_SHEB9
Sequence: MSAVTLQQGDLLLNLYIQPKASRDQIVGLHGDELKVAITAPPIDGKANAHLSKYLAKTFKVPKSDIHIMKGELGRHKQIRVIDPKIIPSIITELMGQTS
What are the official names of this protein?
UPF0235 protein Sbal195_3186.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: NEU2_HUMAN
Sequence: MPDTMLPACFLGLLAFSSACYFQNCPRGGKRAMSDLELRQCLPCGPGGKGRCFGPSICCADELGCFVGTAEALRCQEENYLPSPCQSGQKACGSGGRCAAFGVCCNDESCVTEPECREGFHRRARASDRSNATQLDGPAGALLLRLVQLAGAPEPFEPAQPDAY
What is the function of this protein?
Has a direct antidiuretic action on the kidney, it also causes vasoconstriction of the peripheral vessels.  Acts by binding to vasopressin receptors (V1bR/AVPR1B, V1aR/AVPR1A, and V2R/AVPR2) (PubMed:18174156).
What are the official names of this protein?
Vasopressin-neurophysin 2-copeptin, AVP-NPII.
What is the protein family that this protein belongs to?
Belongs to the vasopressin/oxytocin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RR5_THAPS
Sequence: MSTEFNQVNKLKKTPRRNDNLNEAKFVERLIKISRVTKVTKGGKKLSFRAVVVIGDENGKVGVGVGKAEDVVNAFKKAKTDGRKNLIDVPITKSLSIPHAVIGDLGACKIIMRPSIEGSGVIAGGAVRTVLEVAGIKNVIAKQLGSDNLLNNARTAIVALESLTTLDEVKRKRYHKSVL
What is the function of this protein?
With S4 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1374_METJA
Sequence: MRVEIIFLGCGGGRWATITQKKATGGFRIHTNELRMHVDPGPGAIVRLNELKISPWRTNALFISHCHPDHYTDGEIIVEAITQGMTKKRGVFLGSLSVVEGFGEYEYVVSKYHQSKLEEVRVLYPGDSAELYDTTIKATHTKHGDPFGIGFRLSTIYGDIGYTSDTEFIPQLIEDFDGVRILIANIVRKKNERIKGHLCSNDAIDLINSMNKKPELLIMNHMGVKMTNPQIEAEYISQNTGIEVIPARLGLKVELLNGKYKYQLIK
What are the official names of this protein?
Uncharacterized protein MJ1374.
Protein: RS14_CHLPN
Sequence: MAKKSSVAREAKRRRLVEANFKKRSDLRKIVKSLSVSEEEKENARISLNKMKRDTSPTRLHNRCLLTGRPRGYLRKFAISRICFRQMASMGEIPGVIKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: MTAB_TREPA
Sequence: MFSVRIETLGCRLNHVESESLAALFLQEGFAVCRGNTSTAPVVLCVINTCTVTSKAEQKARRLVRLLLRTYPTAIALVTGCYAQLEPASLEAMDDRVLAFPGKQKDALSLLPSCLRALLVQRGPAPIDQYVCGMRALLASLKKKIISLELTSEFPSQTHMPTRNALPQLTGVPHAPRVSVSSFSEPTAVPRFALYAPRFLFHSRASIKVQDGCNSGCAFCRIRFARGRAVSLETHEVIGRVQALEARGMSEVVLTGVNLSQYRSGSIDFAGLLELIVQETHTIHIRISSLYPESVTSAFLRAIAHTRVSPHFHLSVQSGSDRVLRRMRRAYTRADIYQAVSDLRSVREEPFLGCDIIVGFPGETEEDFADTQRMCKTLRFAGIHVFPFSARPGTEAFAMDAKVPQRIAGERVAAMQQLAEKNYRAYLEYWNGRELCAVVEQSVARVLTENYLSLPIIERGGVAASAGSHVRIRVHNEGAILL
What is the function of this protein?
Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
What are the official names of this protein?
Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB, tRNA-t(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MtaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOS_MOUSE
Sequence: MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTQSAGAYARAGMVKTVSGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEASTPESEEAFTLPLLNDPEPKPSLEPVKSISNVELKAEPFDDFLFPASSRPSGSETSRSVPDVDLSGSFYAADWEPLHSNSLGMGPMVTELEPLCTPVVTCTPGCTTYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL
What is the function of this protein?
Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor.  On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex, at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling (By similarity).  Has a critical function in regulating the development of cells destined to form and maintain the skeleton.  It is thought to have an important role in signal transduction, cell proliferation and differentiation.  In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A.  This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.
What are the official names of this protein?
Protein c-Fos, Cellular oncogene fos, FBJ osteosarcoma oncogene, Transcription factor AP-1 subunit c-Fos.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Fos subfamily.
What are the subcellular locations of this protein?
Nucleus. Endoplasmic reticulum. Cytoplasm, cytosol. Note=In quiescent cells, present in very small amounts in the cytosol. Following induction of cell growth, first localizes to the endoplasmic reticulum and only later to the nucleus. Localization at the endoplasmic reticulum requires dephosphorylation at Tyr-10 and Tyr-30 (By similarity).
Protein: GRPE_SYNJB
Sequence: MAPEDTYPELQEEEIDVEAELEKLILEDSEAEAGTSSGETAAEPSPDPGEALKQLQHELEVVRQQLKEKEDAYLRLYADFENYRRRTQREKEEFSQKERQKFVLEILPVVDSFERAQQQLKLETDRERELHNSYQSVYRLLVECLKKMGVSRMKSVGQPFDPNLHEAIARQPSPDYPEDVVAVEYQPGYKLGDLVIRHAMVAVSAGSPSSEPSPPAQATIEAGPENTPASPQNPQPS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL31B_NEIMF
Sequence: MKPNIHPDNYRTVLFFDSSANEGWLIRSCAETHGKTMVWTDGKEYPLFSLDTSSASHPVYTGKQRNVNTEGRASKFNQRFQSVMSSFRKDK
What are the official names of this protein?
50S ribosomal protein L31 type B.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
Protein: GRCR2_DROME
Sequence: MAAITSNVSRLEPMRGISIIIESPEVATATPPPATTTATAEAEAATKQVAPTAKSNSNTEMSLKSQAAGMLLAFGDTAATAKDNLETSYDTAAKSTAAPETNKIYPQLLLRIGGEIAGATASAEAAASAATAAAATATSPTIISCNGEIAASQAAATAADTAATLQHNNTVKIQIESQGQQRTLGKQISVVKLNEGVEEMQQHMCYLVDTSGQYSPCETLDSGTGSDLENHPQQQQQPQQVRSPQLELHLQTTRLMVNEEADHKHSPLETPSPVPKRAYSLTDDSEECDESSNSSLSCDSLHSGGLLPTTLLRDIRFRERASGPLVTKINGRPLQFETDGYYTFHVREHENFRSFGSNSSTEYEAQHFTDEQPGEDFVGFRDIRTAGKLAGNSTIKSAKGTVRGVKNRVRNGVATFLQLQQPNVKNYMEKDVGKVVLYTTSMGIIRDTYAKCANVKKILRTLLIKFEERDIFMSVEYQQEMRERMQDETIRVPQLFVEGQLIGDANIVERLNESGELRQLLRPYKSIATAYTCQTCGGYRMLPCPACNGSKKSMHRNHFTAEFVALKCMNCDEVGLIKCPNC
What are the official names of this protein?
Glutaredoxin domain-containing cysteine-rich protein CG12206.
What is the protein family that this protein belongs to?
Belongs to the GRXCR1 family.
Protein: PRL_CAMDR
Sequence: LPICPSGAVNCQVSLRDLFDRAVILSHYIHNLSSEMFNEFDKRYAQGRGFMTKAINSCHTSSLSTPEDKEQAQQIHHEDLLNLVLRVLRSWNDPLYHLVTEVRGMQEAPDAILSRAIEIEEQNKRLLEGMEKIVGQVHPGVKENEIYSVWSGLPSLQMADEDTRLFAFYNLLHCLRRDSHKIDNYLKLLKCRIIYDSNC
What is the function of this protein?
Prolactin acts primarily on the mammary gland by promoting lactation.
What are the official names of this protein?
Prolactin, PRL.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: CHEB2_GEOMG
Sequence: MRKIRVVVIDDSAFNRRAIIKMLESMPEVVVAGYANDGEEGIRKVIDLKPDLVTLDLEMPKMDGFTLLRIIMGYCPTPVIVISAKSDDEKVFKALELGAVDFVAKPSQGISEELLTITDDIQQKVRGVFSLNMKEIIRREKVEVLAPPPVAPKKAEAEPRRVVPCRLDVVAIGSSTGGPPAIQRILSSFREALPLAIVISQHMPAGFTRTFAERLNRLSVFEVKEAADGDTVWPGRVLIAPGGHNMVFEKSSGSVVVRVRKPSPEDRYIPSVDAMLASCAEVFGPRTLGVVLTGMGNDGSRGVRAIKGAGGQALAEAESSAVVFGMPREAIATGVVDKVVPLDLIAREIRMRCGVATDLD
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCBK_SHIFL
Sequence: MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNNLHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTRKPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRAGGVGYYPRSNFVHIDTGPARHW
What are the official names of this protein?
Uncharacterized protein YcbK.
What is the protein family that this protein belongs to?
To H.influenzae HI_1666.