PharMolix/UniProtQA huggingface dataset:
Protein: YM085_YEAS8
Sequence: MEFYLSSDCASLARYVSKVVYLEDNDIAHIYDGELHIHCSKIGSEDFLFRTVQKLELELSKIKKGPYDNFMQKEIYEQCETTKNVMRGRVDAFTNRVVLGGLENWLTELRRAKRIIMIASKSSFHSCLAARPIFEELMEVPVNVELALDFVDRNCCIFRNDVCIFVSRSGETTDTINALNYCIKKEAVTIGVVNCSGSSISRFTHCGVHTNTGPEKGIATTKSYTSQYIALVMIALWMSEDLVSKIERRKEIIQALTIVPSQIKEVLELEPLIIELCDKKLKQHDTFLLLGRGYQFASALEGASKMKEISYVHSESILTDELGHRVLAVASDNPPIIAFATKDAFSPKIASCIDQIIERKGNPIIICNKGHKIWEQDKQKGNVVTLEVPQTVDCLQGILNVIPLQLISYWLAIKKDIGVDLPRDSAMSAPDI
What are the official names of this protein?
Uncharacterized protein EC1118_1M3_2531g.
Protein: VE1_BPV2
Sequence: MANDKGSNWDSALGCSYLLTEAECESDKENEEPGAGVELSVESDRYDSQDEDFLDNASVFQGNHLEVFQALEKKAGEEQLLNLKRKVLGSSENSSGSEASETPAKRQKAGAKRRLFSENEANRVLTPLQVQGGEWRQGFNEDQAISHRLLQLVKSKNATVFKLGLFKSLFLCSFHDLTRLFKNDKTTNQQWVLAVFGIAEVFFEASLELLKKQCSFVQMQKRSHEGGTCAVYLLCFNTAKSRETVRNLMANMLNVREECLLMQPPKIRGLSAALFWFKSSLSPATLKHGALPEWIRAQTTLHDSLATEKFDFGTMVQWAYDHKYAEESKIAYEYALAAGSDSNARAFLATNSQAKHVKDCATMVRHYLRAETQALSMPAYIKTRCKLATGEGSWKSILTFFNYQNIELITFINALKLWLNGIPKKNCLAFIGPPKTGKSMLCNSLIHFLGGSVLSFANHKSHFWLASLADARAALVDDATHACWRYFDTYLRNALDGYPVSIDRKHKAAVQIKAPPLLVTSNIDVQAEERYLYLHSRVQTFRFEQPCTDESGEQPFTITDADWKSFFVRLWGRLDLVDEEEDSEEDGDSMRTFTCSARNTNAVD
What is the function of this protein?
ATP-dependent DNA helicase required for initiation of viral DNA replication.  It forms a complex with the viral E2 protein.  The E1-E2 complex binds to the replication origin which contains binding sites for both proteins.  During the initial step, a dimer of E1 interacts with a dimer of protein E2 leading to a complex that binds the viral origin of replication with high specificity.  Then, a second dimer of E1 displaces the E2 dimer in an ATP-dependent manner to form the E1 tetramer.  Following this, two E1 monomers are added to each half of the site, which results in the formation of two E1 trimers on the viral ori.  Subsequently, two hexamers will be created.  The double hexamer acts as a bi-directional helicase machinery and unwinds the viral DNA and then recruits the host DNA polymerase to start replication.
What are the official names of this protein?
Replication protein E1, ATP-dependent helicase E1.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E1 protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: DA_DROME
Sequence: MATSDDEPMHLYEVFQNCFNKIANKQPTGTVGADRGGGGGYHSPYGSLGVENGMYPSDFNSMHDTVNGGNNRYANASTVDQYFDSAAAGSGGAWCQPQMSSANSYMGQSAYQNSGPLSGHSIDQQQQQVHQADGLGMGGGGGGGVGADGMHCPVTTGLPPISSFRPTSGGIGGPGAGQQAPVNVNVNPPAVFNSPQAHNHNHTVQAQHSALSTAGPLGHHSLNHTPHAHSHTLPLPHALPHGHTLPHPHHSQQNSPAVQSSDAFSGAGASVKVAGAGNSSAAALRQQMYMPADQSISSFGSNPSTPVNSPPPLTQSVVGGGGEPSVSGGSGWGHSVLNGGPSSSYASEMVPVSSLHTMASVFQGVRMEERLDDALNVLRNHCEPEMLAGVNQSLASIDNIDALTSFVPNSPSHLGSGGNSGSVSNTSNAALVHEVLALGAAAAAGTSGQSVGGAGSLASLKLDRSASTSLPKQTKKRKEHTAISNSVPAGVSTTSSLTSLDISDTKPTSSIESSNSGLQQHSQGKGTKRPRRYCSSADEDDDAEPAVKAIREKERRQANNARERIRIRDINEALKELGRMCMTHLKSDKPQTKLGILNMAVEVIMTLEQQVRERNLNPKAACLKRREEEKAEDGPKLSAQHHMIPQPQQVGGTPGSSYHSQPAQLVPPSSQTISTMTISLPVNQANNGLPPHLQQQQQQQSQLGHAQLPQ
What is the function of this protein?
Daughterless/Achaete-scute complex heterodimers act as transcriptional activators of neural cell fates and are involved in sex determination.
What are the official names of this protein?
Protein daughterless.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL27_ANOFW
Sequence: MLRLDLQFFASKKGVGSTKNGRDSIAKRLGAKRADGQFVTGGSILYRQRGTKIYPGLNVGRGGDDTLYAKVDGIVRFERMGRDRKKVSVYPVVKEA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: Y1487_TREDE
Sequence: MSGHSKWATIKHAKGAADAKRGQLFTKFIKEISIAAKMGGGDPATNPRLRTAVLKARAANMPKDNIERAIKKGTGELGAVNYEELLYEGYGPGGVAVLVEVLTDNKNRTAASVRNIFTKSGGNLGATGSVAYMFNRKGVIEYDAEVVSEEAIMEAALEAGAEDIATEDGVITVTTDPNDFASVLEALQEKGFESVSAAVSMVPDTYVALDADTTQKALKMIDKLEEDDDVQTVSSNIEIPEGFEMPE
What are the official names of this protein?
Probable transcriptional regulatory protein TDE_1487.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTH_SYNSC
Sequence: MATDLKLVVGLGNPGAKYAGTRHNIGFMALELLGERSGFSFRQQAKLHGLAADTGVGEQRLRLLMPQTYMNDSGRAIRAALDWFGLEPHQLLVLVDDMDLPLGRLRLRAQGSAGGHNGLRSTIQHLGTQAFPRLRIGIGAPAENPAERRVRTVSHVLGPFSKVEQPCVGAVLDAVLDGIQRLQRQSFERAGTWINGFRYDLEPVD
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOB_ECO57
Sequence: MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAWKNPHERDMSYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEFYGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMTPDTDEYYNAAAL
What is the function of this protein?
Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
What are the official names of this protein?
Biotin synthase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Biotin synthase family.
Protein: YME2_PICGU
Sequence: MIRTFATIANRGPGIRLATLAASRNLGYSSGGRISSVRIEKLRFSPFRSSTSLRYTSDIQHVMQEADSLDVNNSVSNTGVLDYDRKNAVVLYFDHIYPFSVSRYSWKQYFTLLFPVNRCSEDDIRERVMNLSSTEKEPLPKDVRILELVPMRRDGGVFVKFQLPATMSARELVGLICQNTKENEQAYGERFLVGPLNKIWNHFPRCFQVKGTPWIEDLRRFPSVKLSVKFEGERLTEEELYVLFRRYGLIIDIAPGSGTEPAVIHFRKIRSAICAKNCVTGITLNSGNTVVHIQYLPLKRVNYITDFIGNHQRIAIPIILALLATAAVFIFDPIREWFIMQNVSHRHALDSYKDNKFLKLVSLPYEQVRRWIDSGYDYFDSKFGCDEEDEFGGEKGEAPNDLWSERYEKVKQLKLWIYENINTFIIVRGPKGSGKEELVLEHTLRDDPILGNKLLYIDCEALVKSRSDNALIEATAQQLGYFPVFTWTNSISQFVDLGVQGLTGQKSGLSESKETQLKNMFGLTSSAIRKLALQDYAKYKKSVLRQRRRQQGDSTSEDILSEDEYLSQHPERKPVIVIDKFAGRADGDQDFIFKMISEWSAQLVQSNLAHVIILTHDVGSMSHLTSALPNQVMKSISLSDASQRSARHYVLNQLNKESQAQVNELDSCLEPLGGRMLDLQAFVRRMRSGEAPGDALEEMVSQASEQITTFFLSASSTQNSWSTAQVWLLIKLLAKQESISYETLCHDPLFKSPDSLSILSTLEKHDLISLISDKGVLNTVSTGRPLYKAAFRSLVEDPKIFRIYEEDLYNKLIALENAKIAKLEDEFAKLASVDARLVRNRLDYVSNKIVASTDKITDYEEKISGLSSKKSSWF
What is the function of this protein?
Plays a role in maintaining the mitochondrial genome and in controlling the mtDNA escape.  Involved in the regulation of mtDNA nucleotide structure and number.  May have a dispensable role in early maturation of pre-rRNA (By similarity).
What are the official names of this protein?
Mitochondrial escape protein 2.
What is the protein family that this protein belongs to?
Belongs to the YME2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: GLGA_NOSP7
Sequence: MRILFVAAEAAPIAKVGGMGDVVGALPKFLREMGHDVRIFLPYYGFLPDKMEIPKEPIWRGSAMFQEFAVYESVLPGTDVPLYLFGHPVFLPRRIYSGDDEDWRFTFFSNGAAEFAWNYWKPDIIHCHDWHTGMIPVWMHQDPDITTVFTIHNLAYQGPWRWYLEKITWCPWYMQGHNTMAAAVQFANKVNTVSPTYAEQIKTPAYGETLEGLLSFISGKLSGIINGIDTEVYNPEDDKYIAQTFTTETLDKRKANKIALQEEVGLEVNSKAFLIGIVTRLVEQKGIDLILQILDRFLSYTDAQFVLLGTGDRYYETQMWQLASRFPGRMATYLLYNDALSRRIYAGTDAFLMPSRFEPCGISQMMSLRYGSVPIVRRTGGLVDTVSHHDPENAAGTGYCFDRYEPLDLFTCMIRAWEGFRFKPQWQELQKRGMSEDFSWYKSAKEYVKLYRSIYGLPEEEETPKPELVLNEAVTNSKS
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: SYY_STREM
Sequence: MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIKEQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTVNYMMSKDSVKKRIETGISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAELKQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAREDLQNGAIYLNGERLQDLDYSLSTADRIDNQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y759_PYRIL
Sequence: MRFDPSEIGEVLEMLLFRELDIRAVTLSVNTLPAIRPTVGDTLAALEETLEPLLKRLRPAVERVASRLGVKIVTVRLAVSPISIMLEPIGKAEAAVEIAKHLDGLAEKHGVDMVGGFSAFVHAGVSRGDAALMEALPEALNSTRRLAGFLNVASTATGVNMDAVRAAAEAVLKMEPHAAARFAATANMPEDVPFMPGAYHGLGLPDAVVNIAVSGPGVIEAVVRNMPNADVRTLHDAIKRAAFKITRLGELVGREVAKELGVPFGSVDLSVAPSPKVGDSVAAILEAVGLPRVGAPGTLFALALFVDAVKKGGAMATSTIGGLSGAFIPVSEDVVMAEAAREGALTFDTLKSTLAVCNTGIDMAGIPGDAPPDAVAALIADVMAVAVALDKALGVRLVPIPGAKPGDVYDLGGLYGRVVVMDLGKYRDIPLARRKGTAPPAVERLKKG
What are the official names of this protein?
UPF0210 protein Pisl_0759.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: RECF_STRP3
Sequence: MWIKELELKHYRNYDQLLASFSSGLNVFIGNNAQGKTNFLEAIYFLSLTRSQRTRADKELIHFDHSTVSLTGKIQRISGTVDLEINLSDKGRVTKINALKQAKLSDYIGTMMVVLFAPEDLQLVKGAPSLRRKFIDIDLGQIKPVYLSELSHYNHVLKQRNSYLKSAQQIDAAFLAVLDEQLASYGARVMEHRIDFINALEKEANTHHQAISNGLESLSLSYQSSVVFDKKTNIYQQFLHQLEKNHQKDFFRKNTSVGPHRDDLAFYINGMNANFASQGQHRSLILSLKMAEVSLMKALTGDNPILLLDDVMSELDNTRQTKLLETVIKENVQTFITTTSLDHLSQLPEGIRIFHVTKGTVQIDSDIH
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPE_BURO1
Sequence: MSATLALTEQLIARASVTPDDQHCQQIMTERLAALGFECETIASHGVTNLWAVKRGTDGRDGKLLAFAGHTDVVPTGPLEQWTSPPFVPAHRDGKLYGRGAADMKTSLAAFVVASEEFVAAHPDHRGAIAFLITSDEEGPATDGTVKVVELLQERGERLDYCIVGEPTSTAELGDVVKNGRRGSMSGELVIKGVQGHIAYPHLAKNPIHLLAPALAELAAEQWDAGNEYFPPTTWQVSNLHAGTGATNVIPGHADLLFNFRFSTASTVEGLQARVHAILDKHGLEYTLKWSVSGLPFLTPRGELSGALEHAIRTETGITTELSTTGGTSDGRFIARICPQVIEFGPPNGSIHKIDEHIEVRFVDPLKNVYRRALEQLIA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: RRF_PSEE4
Sequence: MINDIKKDAQERMGKSIEALGRNLASIRTGRAHPSILDSVKVPAWGSDMPLNQVAAITVEDARTLKIVAHDKNLSAAIEKAILTSDLGLNPSSAGTTIRVPMPALTEETRKGYTKQASSVAEDAKVAVRNVRRDALADLKKLTKDKEISEDEERRAADEIQKLTDKFVAEIDAAFKAKEKDLLAV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_STRP1
Sequence: MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYETASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIQNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAKCQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAKTFIALGASRLGTSRIIKIVKNEATKTDSY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAUB_SHISS
Sequence: MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFARRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS
What is the function of this protein?
Part of the ABC transporter complex TauABC involved in taurine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Taurine import ATP-binding protein TauB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IMQC_ASPFN
Sequence: MIENLRKRSTIEVEWRKQPVHMDIDLDQVDNPEAYPITVSVETSKDGSDPGLLWQPMHAERDSIVKETIHAKYVLGCDGARSWIRQRLGVSFIGDLTDSTWGVMDIVPKTSFPDIRKVAVIHSSKGTVMSVPREDKLVRFYIQIDAVNPNAASGLARRDLKVEDLLDAARAIMFPYTMEAAECAWWSAYRVGQRVANEFARHDRIFLAGDSVREYCLEVIRCQ
What is the function of this protein?
FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of imizoquins A to D, tripeptide-derived alkaloids that serve a protective role against oxidative stress that are essential for normal germination (PubMed:29182847).  ImqB is a canonical three-module NRPS that assembles the tripeptide backbone of the imizoquins via condensation of Trp, Tyr, and Leu-derived precursors (PubMed:29182847).  N-methylation by imqF and phenol oxidation by imqC, followed by cyclization via the FAD-dependent oxidase imqH carry out the three-step transformation of L-tyrosine into tetrahydroisoquinoline (PubMed:29182847).  Importantly, this sequence requires the presence of a free amine in the tyrosine moiety, indicating that isoquinoline formation occurs prior to peptide bond formation (PubMed:29182847).  The imidazolidin-4-one ring of imizoquins could form following additional oxidation of the methyl-derived bridgehead carbon by imqH (PubMed:29182847).  Lastly, O-methylation by imqG and leucine hydroxylation by imqE complete biosynthesis of the imizoquins (PubMed:29182847).
What are the official names of this protein?
FAD-dependent monooxygenase imqC, Imizoquin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the PheA/TfdB FAD monooxygenase family.
Protein: HIS4_BIFLS
Sequence: MSLTLLPAVDVRDGKAVRLRQGESGSETDYGSPFEAARTWVEAGAEWIHLVDLDAAFGTGNNRDQLREIVHELGDRVNIELSGGVRDDASLDAALEAGAARVNIGTAALENPDWTASVIKKYGDRVAVGLDVRGHTLAARGWTREGGDLFETMKFLDSVGCSRYVVTDVAKDGMMSGPNIQLLREVAERTDAKVTASGGISKLDDLRAIKELAEIGVDSAILGKSLYARAFTLQEALAVAK
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROK_CALS4
Sequence: MKNIVLTGFMGTGKTTVGKKVATTLHFNFIDTDKLVEKMAGMSVAEIFEKHGEEYFRKLEKAAVIKASRLKNHVIATGGGVVLNPSNIVQLRKNGVIILLKARPEVILRNISKTKDRPLLAVEDPEKRIRELLEEREPFYRFADYTIDVSDKTIEEVAEEVIRAYIKLKGR
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURC_PSEF5
Sequence: MVENQKAMPQPEMRRIRRIHFVGIGGVGMCGIAEVLLNLGYQVSGSDLKASPVTERLESFGAQIFIGHRAENAANADVLVVSSAVNTSNPEVATALERRIPVVPRAEMLAELMRYRHGVAVAGTHGKTTTTSLLASVFAAGGLDPTFVIGGRLNAAGTNAQLGTSRYLIAEADESDASFLHLQPLVAVVTNIDADHMATYDGDFNKLKKTFVDFLHNLPFYGLAVMCLDDPVVREILPQVKRPTVTYGFSEEADVRAINVRQQGMQTFFTVLRRDREPLDVSVNMPGNHNVLNSLATICIATDEGISDEAIVQGLSGFQGVGRRFQVYGELPVEGGNVMLVDDYGHHPTEVAAVIKAVRGGWPERRLVMVYQPHRFSRTRDLYDDFVQVLADANVLLLMEVYPAGEEPIPGADSRQLCHSIRQRGQLDPIYIERGVDLAPLVKPLLRAGDILLCQGAGDIGGLAPKLLGSPLFAGAVAAGKGAK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP2_PSEPK
Sequence: MSQSPSLHQLQELNPFLRRHLGPDATEQQAMLNALGIASRNELIEQTVPPDIRLNRPLDLPAALDEQAALAKLAGYAEQNQVWTSLIGMGYHGTITPTVILRNVLENPGWYTAYTPYQPEIAQGRLEALLNFQQMVIDLTGLPLANASLLDEATAAAEAMALAKRVARNKSNAFFADEHCHPQTLSVLKTRAEGFGFELIVDSVDNLAKHSVFGALLQYPDTHGEVRDLRPLIDQLHSQQALACVAADLLSLVVLAPPGELGADVVLGSTQRFGVPMGYGGPHAAYFACRDDYKRAMPGRIIGVSRDARGNTALRMALQTREQHIRREKANSNICTAQVLLANIAGFYAVYHGPEGLQRIAQRVHRLTFILAAGLEAKGIKRLNQHFFDTLTLNVGGAQAAIIESAEAAHINLRILGRGHLGVSLDETCTEQTVLRLLDIFLGVDHGLEITALDQLALPEGIPASLVRRTPFLAHPVFNLHHSETEMLRYLKQLENKDLALNQSMIPLGSCTMKLNATSEMIPITWPGFAQLHPFAPAAQAAGYKAMIDELESWLCAITGFDAICMQPNSGAQGEYAGLMAITRYHCSRHQPMRTLCLIPSSAHGTNPASAQMAGMEVVIVDCDNDGNVDLADLKAKAHAAGERLSCLMITYPSTHGVYEEGIREICDVVHQYGGQVYMDGANLNAQVGLARPADIGADVSHMNLHKTFCIPHGGGGPGMGPIGIRAHLKPFVASHPVVPVPGLDPNNSAVSAAPWGSASILPISWMYIAMMGPQLADASEVAILSANYLASQLGAAFPVLYRGRNQRVAHECILDLRPLKALTGISEEDVAKRLMDYGFHAPTMSFPVPGTLMVEPTESESKAELDRFVEAMLAIRAEIDEVQQGNWPAENNPLKHAPHTLADVLGVWDRPYSLEQAVAPSAHVRQHKYWPAVNRVDNVYGDRNLFCACVPVEAYR
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (By similarity).
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating) 2, Glycine cleavage system P-protein 2, Glycine decarboxylase 2, Glycine dehydrogenase (aminomethyl-transferring) 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: ABC3G_MACNG
Sequence: MKPQFRNTVERMYRGTFFYSFNNRPILSRRNTVWLCYEVKTRGPSMPTWGTKIFRGQVYSKAKYHPEMRFLRWFSKWRQLHHDQEYKVTWYVSWSPCTRCANSVATFLAKDPKVTLTIFVARLYYFWKPDYQQALRILCQKRGGPHATMKIMNYNEFQDCWNKFVDGRGKPFKPRNNLPKHYTLLQATLGELLRHLMDPGTFTSNFNNKPWVSGQHETYLCYKVERLHNDTWVPLNQHRGFLRNQAPNIHGFPKGRHAELCFLDLIPFWKLDGQQYRVTCFTSWSPCFSCAQEMAKFISNNEHVSLCIFAARIYDDQGRYQEGLRTLHRDGAKIAMMNYSEFEYCWDTFVDRQGRPFQPWDGLDEHSQALSERLRAILQNQGN
What is the function of this protein?
DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility.  After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA.  The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells.  Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA (By similarity).
What are the official names of this protein?
DNA dC->dU-editing enzyme APOBEC-3G, Deoxycytidine deaminase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, P-body. Note=Mainly cytoplasmic, small amount are found in the nucleus.
Protein: ACD10_MOUSE
Sequence: MLVRRLFQPSTLHWAWRTTALNHPLGRHQGGLRWTHSGGRSYRAVIFDTGGVLVPSPGTVAVGWEVQNHVPSGTIVKAFIRGGDSGPWIRFIKGEITTEHFLEEFGRLCSEIAKTSVPVSSYFSLLTSEQVTKQFPVMTQAISQIRAKGLQTAVLTNNFHLSSGESFLPLDRKQFDVVVESCLEGICKPDPRIFQLCLQRLSLQPSEAIFLDDLGSNLKVAASLGIHTIKVDRPETAVKELEALLGFPLHLGVPNTRPVRKTMAIPQDALEKYLKGLLGTHSTGPMELLQFDHGQSNPTYYIRLADRQLVLRKKPSGTLLPSAHAIEREFRIMKALANAGVPVPTVLDLCEDSSIIGTPFYLMEYCPGIIYKDPSLPGLEPSRREAIYTAMNQVLCRIHSVDLQATSLDSFGKQGDYIPRQVQTWTKQYRAAETSSIPAMERLIQWLPLHLPRQQRTTLVHGDFRLDNLIFHPEKAEVLAVLDWELSTLGDPFADVAYSCLAYYLPSSFPILRGFRDQDVTKLGIPTVEEYFRMYCLNMGIPPIDNWNFYMAFSFFRVAAILQGVYKRSLTGQASSATAQQSGKLTESMAELAWDFATKEGFRVFKEMPATKTLSRSYHAWAGPRSPRTPKGVRGHSTVAAASPSHEAKGGLVISPEGLSPAVRKLYEQLVQFIEQKVYPLEPELQRHQASADRWSPSPLIEDLKEKAKAEGLWNLFLPLETDPEKKYGAGLTNVEYAHLCEVMGMSLYASEIFNCSAPDTGNMEILVRYGTEEQKARWLVPLLEGRIRSCFAMTEPQVASSDASNIEASIKEEDGCYVINGHKWWTSGILDPRCKLCVFMGKTDPQAPRHQQQSMLLVPMDSPGITVIRPLSVFGLEDPPGGHGEVRFKDVRVPKENILLGPGRGFEIAQGRLGPGRIHHCMRLIGYSERALALMKTRVMSRTAFGKPLVEQGTILADIARSRVEIEQARLLVLKAAHLMDVAGNKTAALDIAMIKMVVPSMAYHVIDRAIQAFGAAGLSSDYPLAQFFGWARALRFADGPDEVHQLTVAKMELKNQSRMQEPAVPRV
What is the function of this protein?
Acyl-CoA dehydrogenase only active with R- and S-2-methyl-C15-CoA.
What are the official names of this protein?
Acyl-CoA dehydrogenase family member 10, ACAD-10.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA dehydrogenase family.
Protein: ROK1_CANGA
Sequence: MDIFRVLTRGASINKKANQKGKTVDYSTADTDNDKVDNKQVEKQLNRELDFFRNKKIVSKVETAKAKLEDSVEDSHQQDNNDDVTEVAYDVKITTKEQASALRKSYKGNITGEDIPLPIGSFEDLISRFSLDKRLLNNLIENHFTEPTPIQCEAIPLCLNGRDLLACAPTGSGKTLAFLIPLLQQIIEEKNFSGVKGLIISPTKELATQIFNECVKLSKRIYLDKKRPLQVAILSKSLGAKLRNKVISDKKYDLIISTPLRLIDVVKNEALDLSNVKHLIFDEADKLFDKTFIEQTDDILNSCTDPSMRKSMFSATIPSSVEETANSIMNDPVRVIIGHKEAANTNIEQKLIFCGNEEGKLIAIRQLVQQGEFKPPIIIFLESIARAKALYHELMYDRINVDVIHAERTAIQREKIIERFKTGELWCLICTDVLARGIDFKGVNLVINYDVPTTAQAYVHRIGRTGRGGRSGKAVTLYTKLDSVAIKPIINVMKQSGCEVEGWMNNISKITKREKEAIKKGKSHKERDQISTVPKVERLKRKKKQDMIRASKRRQLESNAIESAD
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase ROK1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL30_EXISA
Sequence: MAKLAITLTRSTIGRPEGQRVTVRTLGLRKMHQTVVVPDNVAMRGMINKVSHLVTVKEINE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: SYE1_PARL1
Sequence: MSGAPVVRFAPSPTGSLHVGNARAALFNFLFARKNSGKFMLRMDDTDDERSTVEFAAGIEEDLTWLGLRHDLFARQSDRLAAYEAAAAKLKADGRLYPAYETAAELDRKRKRQMARGLPPVYDRAALALTDEDRAKLEAEGRKPHWRFRLDRVHTAFDDLVQGAVEVDGASLSDPVLIREDGRFLYTLPSVVDDIDFAVTHVIRGSDHITNTGVQIQIIRALGAEPPVYAHYSLLNGPEGKPLSKRDDAARFSLRALRDAGFEPMALNSLLARLGTPDAVEPCLSLDELAARFDISRLGRADIRFDPADLAKVNTACLHLMSYEEAKPRLAALGCDLGEAFWEAIKPNLILFSDAADWARVVEGPVEPVIENPDFAAAAAAALPPEPWDESTWALWTDAVKQATGAKGKALFMPLRLALTGLTHGPELKNLLPLIGRERASARLGGLTR
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 1, Glutamyl-tRNA synthetase 1, GluRS 1.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.