PharMolix/UniProtQA huggingface dataset:
Protein: COPZB_DICDI
Sequence: MDETVYQIKAIIVLDNNGKRLCSCFYDPPGTPITPLTEKDKFEKLIFEKCKTSNCELEIIDNKVVIGSKQSDVWIFVVGNSLNSNELALLDVLNTLISLFKKACATDESIMITKKTFLENYALIRLYIDEIVSDGIIFEVDEETILNRVPIADNAAQSLNEAIEMAKEKAKGFGFGFL
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).  The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity).
What are the official names of this protein?
Probable coatomer subunit zeta-B, Zeta-B-coat protein, Zeta-B COP.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURB_LEGPH
Sequence: MSITGMDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGGFSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRRGEIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAARLIESCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCA_ACIB3
Sequence: MKKATQSKAWTTVQIARHPERPQFLDYVGEIFTEFDALHGDRLFGDDGAMVGGLARFDGQPVMVIGQHRGRSTREKLKHNFGMCNPEGYRKSQRLLDMAERFNLPVFTFIDTMGAYPGVGAEERGQAEAIATSLAQLSSLKVPVIATVLGEGGSGGALGIGVADRVIMLSHSIYSVISPEGCASILWKTAEKAAQASEALGLTADKLQSLGIVEYVVDEGEGAHLDPERVMQNLKVVLKQALDELLPMDANERCEARYQRLMKFGSENLGMAS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_FRASN
Sequence: MAGMKIKKGDTVQIVTGKDRGLKGKVIRAIPDQNKVVVEGANRVTRHTRVQQSSRGSQSGGIVTQEAPIHVSNVMIVDPSDGRPTRVGYRFNDDGTKVRISRRTGAEL
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS5_SALPB
Sequence: MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNGRVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEGTGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKSVEEILGK
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: NTPP_PROMA
Sequence: MLILASASQARRNLLEQLSIKYAVMVSHIDEGKYNSQNVKELVQALSFAKTESVVSEYIFNCRKENKALAILGCDSLFEFDGEILGKPRNKSEAICRLEKFSSKSGILHTGHCLMYRQNLNNKVIGKSFDGIICDVVSTRINFSELSNVEITKYVETGEPINCAGGFAIDGKGAVFIKSIEGCYSNVIGLSLPWLRYALNKAGMSLWK
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPC3_MOUSE
Sequence: MAGTVRTACLLVAMLLGLGCLGQAQPPPPPDATCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLLQSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVSLYILGSDINVDDMVNELFDSLFPVIYTQMMNPGLPESVLDINECLRGARRDLKVFGSFPKLIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKPCGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQYVQKNGGKLTTTIGKLCAHSQQRQYRSAYYPEDLFIDKKILKVAHVEHEETLSSRRRELIQKLKSFINFYSALPGYICSHSPVAENDTLCWNGQELVERYSQKAARNGMKNQFNLHELKMKGPEPVVSQIIDKLKHINQLLRTMSVPKGKVLDKSLDEEGLESGDCGDDEDECIGSSGDGMVKVKNQLRFLAELAYDLDVDDAPGNKQHGNQKDNEITTSHSVGNMPSPLKILISVAIYVACFFFLVH
What is the function of this protein?
Cell surface proteoglycan (By similarity).  Negatively regulates the hedgehog signaling pathway when attached via the GPI-anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins (PubMed:18477453, PubMed:23665349).  Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation (PubMed:18477453).  Positively regulates the canonical Wnt signaling pathway by binding to the Wnt receptor Frizzled and stimulating the binding of the Frizzled receptor to Wnt ligands (By similarity).  Positively regulates the non-canonical Wnt signaling pathway (PubMed:15537637).  Binds to CD81 which decreases the availability of free CD81 for binding to the transcriptional repressor HHEX, resulting in nuclear translocation of HHEX and transcriptional repression (PubMed:23665349).  Inhibits the dipeptidyl peptidase activity of DPP4 (By similarity).  Plays a role in limb patterning and skeletal development by controlling the cellular response to BMP4 (PubMed:10964473).  Modulates the effects of growth factors BMP2, BMP7 and FGF7 on renal branching morphogenesis (PubMed:11180950).  Required for coronary vascular development (PubMed:19733558).  Plays a role in regulating cell movements during gastrulation (By similarity).
What are the official names of this protein?
Glypican-3.
What is the protein family that this protein belongs to?
Belongs to the glypican family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Protein: Y223_LAWIP
Sequence: MKSCEIGQQGESAAALFLYNKGMSILERNWRKGRFEIDLVCQDIKTLVFVEVRTRKAKGMLLPEQTLTISKRCNIIHSAQLYLMDKKDWSMPCRFDVICIISKKTTLELEHYKNVFEFYEIMDSSNTSWQPW
What are the official names of this protein?
UPF0102 protein LI0223.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: PRMA_PSYA2
Sequence: MAWQQLHLQCEKDNVDLAEALLLEAGALSIALDDAGDQPLFEPLPGESPLWDEVILTGLFDATTEAGTSHVIEQFSHEIAAQVQASRTWVSAVDDKDWEREWMSNYKPIECANDLWIVPNWLTPPNPEATNIIMDPGLAFGTGYHATTRLCLDWLTEQDLKDKVVIDYGCGSGILGIAALLLGARHVYAVDIDPQAVLATNQNAARNSVDNRLQAFLPEDFTIFCQQQDIPAVEVMVANILAKPLIGLAPYFATLMASKSRIVLAGLIESQTEQVTEAYQPYFALDPKHAFTAQEDQHWQRLSGTFTG
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_PROM2
Sequence: MDLEAKLHEIRKPIMVLGTSSGAGKSLTVTAICRILKNLGEEPIPFKGQNMSNNAWIDWEGGEMAYSQALQAFACGINPSAEMNPILLKPQGNSTSEVIHLGKSIGTTTAQNYYKDWFIPGWEVIKKSLKSIYELNPNCRLIIEGAGSPVEMNLIHRDLTNLRVAKYLNANCLLVTDIERGGVFAQIIGTLELMKPEERKLIKGIIINRFRGDLSLFEDGKKWIENKTQIPVIGIIPWLNDSFPPEDSLDLIEKKSLSKNHEIKVGIIKLPSISNFSDFDPLENEETILIEWIRKSKNLSTYDFIILPGSKQTIKDQKFLENSGLSQDIRDYSNNEGNIIGICGGLQMLGTTLEDPYFKEGAKNYSEQKINGIGLLPLKTTFFKKKLTRQINTKSIWPCQSQINGFEIHNGQTILDDSQSSLKINPIFEDLDLGWFKENNKGGTIAGTYIHGIFENDSWREQYINLIRKSKNLPILNKKSISYKKKRESIIDNLANEFHKHLNLTSFLS
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: PABP5_PONPY
Sequence: MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRRC
What is the function of this protein?
Binds the poly(A) tail of mRNA.  May be involved in cytoplasmic regulatory processes of mRNA metabolism.  Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein 5, PABP-5, Poly(A)-binding protein 5.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBH_MAIZE
Sequence: MATQTVEDSSRPKPKRTGAGSLLKPLNSEYGKVAPGWGTTPFMGVAMALFAIFLSIILEIYNSSVLLDGILTN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein H, PSII-H, Photosystem II 10 kDa phosphoprotein.
What is the protein family that this protein belongs to?
Belongs to the PsbH family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single- pass membrane protein. Note=PSII is more abundant in mesophyll cells than bundle sheath cells.
Protein: BTC_HUMAN
Sequence: MDRAARCSGASSLPLLLALALGLVILHCVVADGNSTRSPETNGLLCGDPEENCAATTTQSKRKGHFSRCPKQYKHYCIKGRCRFVVAEQTPSCVCDEGYIGARCERVDLFYLRGDRGQILVICLIAVMVVFIILVIGVCTCCHPLRKRRKRKKKEEEMETLGKDITPINEDIEETNIA
What is the function of this protein?
Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members.  Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
What are the official names of this protein?
Probetacellulin.
What are the subcellular locations of this protein?
[Betacellulin]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Probetacellulin]: Cell membrane; Single-pass type I membrane protein.
Protein: PPK1_MYCPA
Sequence: MMRHDRNVTEIDAETRPDENLWHSGDSAVGAPPAATPAAMTDLPEDRYLNRELSWLDFNARVLALADDNSLPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPRKQLALIGEHTQRIATRHARVFLDSVRPALAEEGIHIVTWADLDQAERDELSTYFTEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVMVRQTEDGGQHFARVKVPNNVDRFVELAAPRAGAEGENRGVVRFLPMEELIAAFLPLLFPGMEIVEHHAFRITRNADMEVEEDRDEDLLQALERELARRRFGPPVRLEIADDMTEGMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYDLDRPALKDPAFVPDTHPAFADRESPKSIFATLREGDVLVHHPYDSFSTSVQRFIQQAAADPNVLAIKQTLYRTSGDSPIVRALIEAAEAGKQAVALVEIKARFDEQANIRWARALEQAGVHVVYGLVGLKTHCKTCLVVRREGSAIRRYCHIGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKVSYRNLLVAPHGIRTGIIERVEREIAAHRERGQGRIRLKMNALVDEQVINSLYRASQAGVRVEVVVRGICALRPGVQGYSENIFVRSILGRFLEHSRIIHFRNINEFWIGSADMMHRNLDRRVEVLAQVKDPKLTAQLDELFESALDPSTRCWELGPDGQWTPSPQEGHTVRDHQVSLMERHRSP
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: IF1_PSE14
Sequence: MSKEDSFEMEGTVVDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVRVELTPYDLSKGRITYRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IFNA_FELCA
Sequence: MALPSSFLVALVALGCNSVCSLGCDLPQTHGLLNRRALTLLGQMRRLPASSCQKDRNDFAFPQDVFGGDQSHKAQALSVVHVTNQKIFHFFCTEASSSAAWNTTLLEEFCTGLDRQLTRLEACVLQEVEEGEAPLTNEDIHPEDSILRNYFQRLSLYLQEKKYSPCAWEIVRAEIMRSLYYSSTALQKRLRSEK
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha, IFN-alpha.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROD_STRZP
Sequence: MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQVAPAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKDVFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNYTRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKIREILDEA
What is the function of this protein?
Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type I DHQase, Type I dehydroquinase, DHQ1.
What is the protein family that this protein belongs to?
Belongs to the type-I 3-dehydroquinase family.
Protein: PANB_BDEBA
Sequence: MKTILDFHDKKSKKQKISMITCYDYSFARIVADSDIDCILVGDSLAMVMLGHSTTLDVSASVMAHHTAAVVRGAGDKFVIADLPFMSYRKGLTANMTAVEKVMKAGAHAVKLEGAAGNLKLVRHLVDSGVPVMGHLGLTPQSVNQLGGFKVQGRDEKAQKKILEAALQLQDAGAFSVVLECVPSKLAKEITAALEIPTIGIGAGVDCDGQVLVLQDMLGMNQGFKPKFVKTYLDGFNTIKGALNQYHQEVSTEIFPSEKESYS
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CINAL_MYCTU
Sequence: MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGSQVIDPVGTAPGLVVPGRPAVMVLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVTRFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGAVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: CITG_STRPQ
Sequence: MTKAVLTSISQLALKALLYEVSLSPKPGLVDRFDNGAHDDMSFMTFIDSMIALSPFFQAYIETGFAYAKEEPLLLFNRLRQLGQKAEETMFCATQGINTHKGLNFSMALLLGATGAYLARTPHLMTDLGRFSKEDTLAICRLVKPMTAHLIQTDLGHLNTKKEFTYGEQLFVTYGIKGPRGEASEGFTTLTDHALPYFRQMISQNDPETSQLRLLVYLMSIVEDGNLIHRGGIEAWKGVKADMRLLLQQDLSTTDLRLALSSYNQCLINQHLSPGGAADLLALTFYFAFLEKLL
What are the official names of this protein?
Probable 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase, 2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthase.
What is the protein family that this protein belongs to?
Belongs to the CitG/MdcB family.
Protein: RL22_MAGSA
Sequence: MGKKPADRVLADTEAKAFLASIRTSPRKLNLVAESIRGLKADVALNALTFSKRRIAVEVRKVLQSAIANAENNHQLDVDRLYVAEAFVGKAMVMKRWKARARGRVGRIEKPFSNLTVIVRERAEAAGE
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ERG3_ORYSJ
Sequence: MVQGTLEVLLVGAKGLENTDYLCNMDPYAVLKCRSQEQKSSVASGKGSDPEWNETFMFSVTHNATELIIKLMDSDSGTDDDFVGEATISLEAIYTEGSIPPTVYNVVKEEEYRGEIKVGLTFTPEDDRDRGLSEEDIGGWKQSS
What is the function of this protein?
May play a role in plant defense signaling (Probable).  Does not bind to phospholipids in a Ca(2+)-dependent manner in vitro (PubMed:21756975).
What are the official names of this protein?
Elicitor-responsive protein 3, OsERG3, 16 kDa phloem protein, RPP16.
What are the subcellular locations of this protein?
Cytoplasm. Note=Does not translocate to plasma membrane upon fungal elicitor or calcium treatment.
Protein: RL24_SORC5
Sequence: MKRLRVGDLVQVISGKEEGKQGRITKILADEDRVVVEGLNTVTRHQRPTPRNQEGGKITKEAPIHASKVMPVDPATGKPTRVKVRVGEDGKKTRVGKSGSAIGVG
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RL25_GEOUR
Sequence: MEERVLNVELRTKTGKGISRQLRRNNFIPGVVYGKGMESVPVSLSTKELSTAIAGEGGRNHLLTLKGGGGLDGQMVIVAELLQDCLKGTPRHVDLHKINMADKVRVKVPVNLVGSAVGVKEGGLLDFAMHEIEIECFPTHIPEHIDVDVTELTIGHSLHIGDIKELPGIKVLGDATVSVVSILGKVKEEPVVDA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: ARGB_PSEF5
Sequence: MTIERDAAANTAKVLSEALPYIRRYVGKTLVIKYGGNAMESEELKTGFARDIVLMKAVGINPVVVHGGGPQIGDLLKRLSIESHFVDGMRVTDAQTMDVVEMVLGGQVNKDIVNLINRHGGSAIGLTGKDAELIRAKKLTVTRQTPEMTTPEIIDIGHVGEVVGINTDLLNLLVKGDFIPVIAPIGVGANGESYNINADLVAGKVAEALKAEKLMLLTNIAGLMDKSGKVLTGLSTQQVDELIADGTIYGGMLPKIRCALEAVQGGVGSSLIIDGRVPNAILLEIFTDTGVGTLISNRKRP
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDH_CHESB
Sequence: MARHKIALIGSGMIGGTLAHLVGLKELGDVVLFDIAEGIPQGKGLDIAESAPVEGFDAKFLGTNDYAAIEGADVCIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPNAFVICITNPLDAMVWALQKFSGLPKSHVVGMAGVLDSARFRYFLAEEFKVSVEDVTGFVLGGHGDSMVPLIRYSTVAGIPIPDLVKMGWTTQEKIDQIVQRTRDGGAEIVGLLKSGSAFYAPASSAIAMAEAYLKDKKRVLPCAAHVSGQYGVKDLYVGVPTVIGAGGVERIIEIDLNKTEQKMFENSVASVEGLCKACGDIAPSLKN
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: Y564_NOCSJ
Sequence: MADSSFDIVSKIDRQEVDNALGQTAREIATRFDFKGTGASIEWQGEHAIEISASADDRASAVLDVFKTKLVKRDVSLKVLDASEPRQSGQQSKIAIALKEGISSEDAKKISKLIRDEGPKGVKAQIQGDELRVSSKKRDDLQAVIALVKQQDYDFAVQFTNYR
What are the official names of this protein?
UPF0234 protein Noca_0564.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: THAS_MOUSE
Sequence: MEVLGLLKFEVSGTIVTVTLLVALLALLKWYSMSAFSRLEKLGIRHPKPSPFVGNLMFFRQGFWESQLELRERYGPLCGYYLGRRMHVVISEPDMIKQVLVENFSNFSNRMASGLEPKMVADSVLLLRDRRWEEVRGALMSSFSPEKLDEMTPLISQACELLVAHLKRYAASRDAFNIQRCYCCYTIDVVASVAFGTQVDSQNSPEDPFVQHCRRASTFCIPRPLLVLILSFPSIMVPLARILPNKNRDELNGFFNTLIRNVIALRDQQAAEERRRDFLQMVLDAQHSMNSVGVEGFDMVPESLSSSECTKEPPQRCHPTSTSKPFTVDEIVGQAFLFLIAGHEVITNTLSFITYLLATHPDCQERLLKEVDLFMGKHPAPEYHSLQEGLPYLDMVISETLRMYPPAFRFTREAAQDCEVLGQRIPAGTVLEIAVGALHHDPEHWPNPETFDPERFTAEARLQRRPFTYLPFGAGPRSCLGVRLGLLVVKLTILQVLHKFRFEASPETQVPLQLESKSALGPKNGVYIKIVSR
What is the function of this protein?
Catalyzes the conversion of prostaglandin H2 (PGH2) to thromboxane A2 (TXA2), a potent inducer of blood vessel constriction and platelet aggregation.  Cleaves also PGH2 to 12-hydroxy-heptadecatrienoicacid (12-HHT) and malondialdehyde, which is known to act as a mediator of DNA damage.  12-HHT and malondialdehyde are formed stoichiometrically in the same amounts as TXA2.  Additionally, displays dehydratase activity, toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE) producing 15-KETE and 15-HETE.
What are the official names of this protein?
Thromboxane-A synthase, TS, TXA synthase, TXS, Cytochrome P450 5A1, Hydroperoxy icosatetraenoate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: APT_AERHH
Sequence: MNPETLKFIEASIKTIPDYPKPGILFRDITSLIENADAFKATIDLLANHYRDQGITKIVGTEARGFIFGAPVAYAMGLGFVPVRKPGKLPRAVIEESYALEYGTDTLQLHTDAIVPGDKVLVVDDLLATGGTVDATVKLIRRAGGEVVDAAFIISLPSLGGDARLTAAGVKVVSLVELPGE
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.