PharMolix/UniProtQA huggingface dataset:
Protein: TIG_HERAR
Sequence: MATAVETLDKLERRITITVPVAEVQTEVEKRLKVRARTVKAPGFRAGKVPMKMVAQQYGYQIENEVLNDKVGQAFGEATSENKLRVAGYPKIEAKNDDVAEGTLAFNATFEIYPEIKVGDLASAEVEKTIVEVSDAEIDKTIDILRKQRVHYHVKGEQSAHGDGGSDLTAKNSDRVTIDFVGTINGVEFQGGKAEGYAFVLGEGRMLAEFEAGTIGLKVGESKTFPLSFPADYHGADVAGKTAEFTITLKQIEWAHMPEVDAEFAKSLGIEDGDLEKMRADVKQNLEREVSNRVKARTKDSVMDALIKISEFDVPKVLIDQETQRLMESTRQDMAQRGMKVSDLPFPPELFTEQAERRVRLGLILAEVVKANELQAKPEQVKAQVEEFAQSYEDPTQVLKYYFSDRSRLAEVEALVLEENVVNYVLGKAKVADKSVAFDELMGNNAQG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: FAPR_HALH5
Sequence: MKRKKQDRQRHLKETIDANPFITDEALADRFGVSIQTIRLDRMELSIPELRERIKDVAQKQLDEVKALPMEEVFGEIVDLQLDERAISILDVKKEHVFSRTGIARGHYLFAQANSLAVAIIDDDLALTAKATIRFTRQVKAGERVVAKAEVQKVERDRTLVVVNSFVEQELVFSGDFLMYRSAQEQ
What is the function of this protein?
Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism.
What are the official names of this protein?
Transcription factor FapR, Fatty acid and phospholipid biosynthesis regulator.
What is the protein family that this protein belongs to?
Belongs to the FapR family.
Protein: ABP20_PRUPE
Sequence: MPQATMIFPILFTFFLLLSSSNAAVQDFCVADLAAPEGPAGFSCKKPASVKVNDFVFSGLGIAGNTSNIIKAAVTPAFVAQFPGVNGLGISIARLDLAVGGVVPFHTHPGASEVLIVAQGTICAGFVASDNTPYLQTLEKGDIMVFPQGLLHFQVNGGEAPALAFASFGSASPGLQILDFALFKNDLPTEVIAQTTFLDAAQIKKLKGVLGGTN
What is the function of this protein?
Probable receptor for the plant growth-promoting hormone auxin.
What are the official names of this protein?
Auxin-binding protein ABP20.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast. Secreted, cell wall.
Protein: DNJ5_CAEEL
Sequence: MSSFDDPEKHFLGNLLEDDPGSSVTSATSPFAGINGSTSTALTSQVPTVGPVMCPTELSMSNAWPEPPPPYSPRHESWGLPSNANTTLLGSSSLTSSNWFPFTDQKETSSNEILSSLNLAAGSSSPALPSTPSRVPHHPSSQVHHFHHNLHHHTHTHNVQVQNHYFGAPPPGLESFGPTRTSSTSSSQIYDAIPNPSWNYTGLSNINADSNVLFSDWKNKNSSQTSPVSTVVSESSISSNLETRPVHPPLSPSEVVEIAKEKKNVSKSYAEHLSKSTAGTQKKGAPIGAEKKQKQELAKKMSNQLPIESIATRIVVKGQPHSAPVVSRMPFSYRDVAARSDHTSSSNHPNHQPDELQRKELSSADLKLNDSKAVRTKNNDHRETGKTRNTIDPTDFNKKNRVDNEFQKINNRKNKKEKAVTEVAAPVIFEGVHPVDSSSRYDVLKNLESPNQSYHEKKSANGRPPLIQKIFSRSSSPADDIIDTEEEDPHRVRSSSTHVHQNGNGQVKKDQRKRVAQVNQRRRKGRKEEPSWLQNAFSTFVDVLFFVWGYACFGLQWTLLLIVEVCQKIADIFVTFGKSLWAGTCKGLRNVILAFVYLCFFVVFAIKSVVVRLLTFINMIGAEESDETVEEQDWGCKKEIPIATNATEFADRLSRETIRDAYSVFGLRSDCSDDDIKRNYKRLAALVSPDKCTIDAADQVYELVDVAFSAIGYKDSRSEYTLENLKNNEVHEQLISVWNDMTKAVEEARNTIFCDCENTHFRVATSISPSQARSCKRCGVKHPAKQNDIWVEKRHLGLTSTYYTCTDNVVYDITSWATCKSQRAMLKNMRAHTHNVQYRLLSPMFKNSDFDAQSQYYNSSYPSSSTDARFLSDLQEEYSTLLRQRSLAQISFKNCEPREEDRSRRAANRRQKRWR
What are the official names of this protein?
DnaJ homolog dnj-5, DnaJ domain protein 5.
Protein: RL31_SHIB3
Sequence: MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRDVATGGRVDRFNKRFNIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PYRG_STRM5
Sequence: MTPLIFVTGGVVSSLGKGIAAASLAAILEARGLKVTMMKLDPYINVDPGTMSPFQHGEVYVTDDGAETDLDLGHYERFVRTRLSRKNSVTTGRIYENVIRKERRGDYLGATVQVIPHITDEIRRCIDEATEGYDVALVEIGGTVGDIESLPFLEAIRQVRTERGPEKALFMHLTLVPYIGAAGELKTKPTQHSVKELRSIGIQPDVLLCRSEQAVPDSERRKIAQFTNVSERAVISVPDVDVLYRIPSGLHAQGLDEIVVNQLKLADKVGPVDLSMWEDAVDATLHPLDEVTIAVVGKYVDHQDAYKSVGEALKHGGLRQRTKVNLKWLEAQDLEGTDMAALADVDGILVPGGFGDRGFEGKVLTSKFAREQQVPYFGICYGMQAAVVDYARNVVGLEGANSTENDRQSPNPVIGLITEWRTATGDVEKRDDKSDLGGTMRLGLQEQRLKPGTLARELYGKDVVAERHRHRYEFNNRYRTQLEDAGLVIAGKSMDDTLVEVVELPRDAHPWFLACQAHPEFLSTPRDGHPLFIGFIRAARERKAGGKLLQEVRA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: TPIS_METMA
Sequence: MGSPFILLNYKTYIQGTGKGAVDIAKACKTVSEESGIEIAVAPQLPDIYRVASEVELSVFSQHMDGIGAGSFTGHVFGKCIKEAGAFGTLINHSERRLTLAEIEASLKAAKEFGLRAIICTNNVPTTAAAAALVPDYVAIEPPELIGSGIPVSKADPEVVSGSVEAVSKINPDVKVLCGAGISKGEDLRAALDLGSQGVLLASGIVKASDPKAALEDLIRLV
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTI_SHEON
Sequence: MSWDQVWIDVNVATMDPSISAPYGAITHAAIAVKDGKIAWLGPRSELPAFDVLSIPVYRGKGGWITPGLIDAHTHLVFAGNRANEFELRLKGATYEEIARAGGGIISTVNACREADEAALFELGRQRLNALAKEGVTTVEIKSGYGLDTETELKILRVARELGKHHHVDVKTTFLGAHAVPPEYKGNSDGYVDLIINKMLPAVIKENLADAVDVFCENIAFNLEQTERVLSAAKAAGLQVKLHAEQLSNMGGSELAARLGAKSVDHIEYLDEAGVKALSESGTCAVLLPGAFYFLRETQKPPIDLLRQYGVPMVLASDFNPGSFPICSTLLMLNMGCTLFRLTPEEALAGLTLNAAKALGIEDKVGSLVVGKQADFCLWNIATPAQLAYSYGVNPCKDVVKNGKLVHQ
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YP55_ECOLX
Sequence: MKAVGRGATPLGGWEAALAAGWGSRRGGTPLRRPIILRGTLGRFAAFFDTRL
What are the official names of this protein?
Uncharacterized 5.5 kDa protein in replication origin region, ORF1.
Protein: YQGF_ORITB
Sequence: MIINSISEFLQAADIKKQILGIDFGEKKVGVAISNIEHTVAMPLQTILATNQDRVNKIQEIAVAYNIGAIVIGLPFKLDGTETSQTHRVKDFANKLANKLLLPIFLCDERLTSKAANNLLKIGNIKRKVRNAIDDRVAASIILEGALKRMQNSKSYF
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUTS2_FINM2
Sequence: MDKKTLNTLEYNEIKNKIEKLCKSKLGKSIANKLEPMIEEDEIRQSLDETYEAMSMIYKFSNPPIYEIINVKASIMHVSKGGYIVPEVLLKIGQILNSVHDIKRYAGESDENYENCPMIMAMMDSLVEEPDLVATINNAIISEDEISDNASRNLARIRQTKRQKTENIRDKINSILSSNDQALQENIVTMRDDRYVIPVKVSHKSSFKGIVHDHSSSGQTVYIEPMEVVELNNELRMLEAEEREEIIRILKEISDRVYDVKDSIFVDQDVLSKLDFIFAKAKYAIEIDATNPKLNTNGYFNFKNARHPLLDKKKVVPISIYLGDDYNTLVITGPNTGGKTVTLKTVGLITLMAQSGILIPVDENSEVAIFDNIFTDIGDEQSIEQSLSTFSAHMKNIVHIVNNITFNSLVLFDELGAGTDPTEGAALAIAILRIFLYKSIRTIATTHYSQLKIFALTEKYVKNGSVEFDVNTLSPTYKLRIGIPGKSNAFEISRRLGLDDDIINNAKEILSQEDKDFEDVLSDIESKKKQIDEDKQRQLELKEDLLKLRDRYEKEIEKTKLEKEKIINEAKENANEIYMRAKEESRELINKLKFLEKESDARTVANDVENKFNKRIKKSSNKKLLNETSKKQKLQLGDEVEILGIEQQGTIVSEPDKKGDLLVQVGILKINANVKNLKKIKEKEVIQSSKSIKSIIKNKANSDIKSEIDLRGKNIEEAIYELDKYIDDCVIVGLKKVNIIHGKGTGMLRKGIREYLRSDKRVKKIEDAGYNEGGLGATFIYLK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: UREG_BURP1
Sequence: MNAPRFAAPARRTKKLPPLRVGIGGPVGSGKTTLLEMLCKGMRERYDLVAITNDIYTKEDQRLLTIAGALPEARIMGVETGGCPHTAIREDASINLEAVERMLVRFPDADIVFIESGGDNLAATFSPELSDLTIYVIDVAGGEKIPRKGGPGITKSDLLVINKTDLAPLVGANLEVMASDTRKMRGERPYVMCNLKALDGVADVIAFIENKGLLTV
What is the function of this protein?
Facilitates the functional incorporation of the urease nickel metallocenter.  This process requires GTP hydrolysis, probably effectuated by UreG.
What are the official names of this protein?
Urease accessory protein UreG.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_BUCAP
Sequence: MNQTIKHISVMKKELIESLKIKKNGIYIDGTFGMGGHALSILKTIGREGRLYAIDRDPNSVFIGNQIKDKRFHIIHSNFSKILNYAKYNNIIGKVNGILFDLGTSSLQIENEKRGFSFKKNGPLDMRMNPHAGISASEWLFKSDINKIYFVLKNFGEERFSKRIAYAIKDYCKKKKINNTFELVDIIKKATPIKNKFKHPAKRTFQAIRIYINQELEEIKKGLENSLKILKPGGRLSIISFHSLEDRIVKNFMMKYSKKATVPYGLPITENKLETLRICKLKIINRIFPTQKEIEKNPRARSSVLRTAELKE
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUPG_BACSU
Sequence: MYFLLNLVGLIVIMAVVFLCSPQKKKIKWRPIITLIVLELLITWFMLGTKVGSWAIGKIGDFFTWLIACASDGIAFAFPSVMANETVDFFFSALLPIIFIVTFFDILTYFGILPWLIDKIGWVISKASRLPKLESFFSIQMMFLGNTEALAVIRQQLTVLSNNRLLTFGLMSMSSISGSIIGSYLSMVPATYVFTAIPLNCLNALIIANLLNPVHVPEDEDIIYTPPKEEKKDFFSTISNSMLVGMNMVIVILAMVIGYVALTSAVNGILGVFVHGLTIQTIFAYLFSPFAFLLGLPVHDAMYVAQLMGMKLATNEFVAMLDLKNNLKSLPPHTVAVATTFLTSFANFSTVGMIYGTYNSILDGEKSTVIGRNVWKLLVSGIAVSLLSAAIVGLFVW
What is the function of this protein?
Involved in the uptake of the purine ribonucleosides inosine and guanosine.
What are the official names of this protein?
Purine nucleoside transport protein NupG.
What is the protein family that this protein belongs to?
Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM6_SYNS9
Sequence: MVRALIRRVLGRQENDQSTPQLELPPTDSRDRARSMVMGLQDEICAGLEALDGEGRFQEESWVRPEGGGGRSRVMREGRVFEQGGVNFSEVQGNELPPSILKQRPEAKGHPWFATGTSMVLHPRNPYIPTVHLNYRYFEAGPVWWFGGGADLTPYYPFLDDARHFHRTHQQACNSVHPNLHKVFKPWCDEYFYLKHRNETRGVGGIFYDYQDSRGTLYKGQDPTGAAAKVSSELGATPLSWEQLFSLGQANGRAFLPSYAPIVEKRHATSYGDRERDFQLYRRGRYVEFNLVWDRGTIFGLQTNGRTESILMSLPPLVRWEYGYTAEAGSREALLTDLFTTPQDWLGDPSLEERCRPHQAIN
What is the function of this protein?
Involved in the heme and chlorophyll biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_STAA9
Sequence: MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFDLVEQRSGRDALEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: GATC_BORBU
Sequence: MKDIHLKNSLKLSLVTLSRESEDKFISKFEKVIKLVNKISNFEVQINFNANKKKISTLREDKVEFSLSIEAIKKLSNSFLDGYFSSPKILE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: COX11_BOVIN
Sequence: MGGLWRPAWRRVVFCGWSWSHLGRPTRAAERAEPCLRPGRSGPAGTEQGLRRLGTWRRPSPAEQPARRPKSTNPYTRSQEEDWRRRNKTVLTYMAAAAVGMLGASYAAVPLYRLYCQTTGLGGSAVAGHASDQIENMVPVKDRIIKITFNADVHASLQWNFRPQQTEIYVVPGETALAFYKAKNPTDKPVIGISTYNVVPFEAGQYFNKIQCFCFEEQRLNPQEEVDMPVFFYIDPEFAEDPRMVNVDLITLSYTFFEAKEGHTLPVPGYNSNQQLSPASNL
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein COX11, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side.
Protein: MSRQ_SALSV
Sequence: MRLTAKQITWLKVCLHLAGFLPLLWLFWAINHGGLSADPVKDIQHFTGRTALKFLLATLLVSPLARYAKQPLLIRTRRLLGLWCFVWATLHLTSYALLELGIHNLALLGSELISRPYLTLGIISWLVLLALTLTSTQFAQRKLGKRWQTLHNVVYLVAILAPIHYLWSVKILSPQPVIYAALALALLALRYRKFRQWWR
What is the function of this protein?
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons.  Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms.  MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal.  MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.
What are the official names of this protein?
Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ, Flavocytochrome MsrQ.
What is the protein family that this protein belongs to?
Belongs to the MsrQ family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UVRD1_MYCBO
Sequence: MSVHATDAKPPGPSPADQLLDGLNPQQRQAVVHEGSPLLIVAGAGSGKTAVLTRRIAYLMAARGVGVGQILAITFTNKAAAEMRERVVGLVGEKARYMWVSTFHSTCVRILRNQAALIEGLNSNFSIYDADDSRRLLQMVGRDLGLDIKRYSPRLLANAISNLKNELIDPHQALAGLTEDSDDLARAVASVYDEYQRRLRAANALDFDDLIGETVAVLQAFPQIAQYYRRRFRHVLVDEYQDTNHAQYVLVRELVGRDSNDGIPPGELCVVGDADQSIYAFRGATIRNIEDFERDYPDTRTILLEQNYRSTQNILSAANSVIARNAGRREKRLWTDAGAGELIVGYVADNEHDEARFVAEEIDALAEGSEITYNDVAVFYRTNNSSRSLEEVLIRAGIPYKVVGGVRFYERKEIRDIVAYLRVLDNPGDAVSLRRILNTPRRGIGDRAEACVAVYAENTGVGFGDALVAAAQGKVPMLNTRAEKAIAGFVEMFDELRGRLDDDLGELVEAVLERTGYRRELEASTDPQELARLDNLNELVSVAHEFSTDRENAAALGPDDEDVPDTGVLADFLERVSLVADADEIPEHGAGVVTLMTLHTAKGLEFPVVFVTGWEDGMFPHMRALDNPTELSEERRLAYVGITRARQRLYVSRAIVRSSWGQPMLNPESRFLREIPQELIDWRRTAPKPSFSAPVSGAGRFGSARPSPTRSGASRRPLLVLQVGDRVTHDKYGLGRVEEVSGVGESAMSLIDFGSSGRVKLMHNHAPVTKL
What is the function of this protein?
DNA-dependent ATPase, acting on dsDNA with a 3'-ssDNA tail, unwinding with 3'-to 5'-polarity.  Also highly efficient on nicked DNA.  Involved in the post-incision events of nucleotide excision repair (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase UvrD1, DNA 3'-5' helicase UvrD1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. UvrD subfamily.
Protein: RL7_SHEFN
Sequence: MSITKDQMLEAFAAMSVMEVVELIEAMEEKFGVSAAAAVVSGGGDAVAAEEQTEFDVVLTSFGENKVAVIKALRSATGLGLKEAKTMAESSPIAVKEAVSKEEAATLKADLEAAGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: LIRA4_HUMAN
Sequence: MTLILTSLLFFGLSLGPRTRVQAENLLKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTAYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRSPPRCSQEANSRKDNAPFRVVEPWEQI
What is the function of this protein?
Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354).  Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades (PubMed:16735691, PubMed:19564354, PubMed:24586760).  Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells (PubMed:26172439).  Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+) (PubMed:16735691, PubMed:19564354).  Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells (PubMed:24586760).
What are the official names of this protein?
Leukocyte immunoglobulin-like receptor subfamily A member 4, CD85 antigen-like family member G, Immunoglobulin-like transcript 7, ILT-7.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DKC1_CAEEL
Sequence: MGKKDKRSKLEGDDLAEAQQKGSFQLPSSNETAKLDASQWPLLLKNYDKLNVRTNHYTPHVEGVSPLKRDIKNYISSGFFNLDKPSNPSSHEVVSWIKRILRCEKTGHSGTLDPKVSGCLIVCIDRTTRLAKSQQGAGKEYICIFKLHEEVEDDRKVKQALEKLTGALFQRPPLISAVKRQLRIRTVYENKFIEYDPAQQMGIFNCICESGTYVRTICVHLGLILGCGGQMQELRRNRSGICDENENMVTMHDVLDAQYLLDTQKDESYMRHIVRPLEALLTQHKRVVVKDSCINAICYGAKILIPGILRYDDDIEVGKEIVIMSTKGEAICIAIAQMNTSTIASVDHGVVAKSKRVIMERDVYGRKWGLGPVASKKKQMVKDGLLDKFGKPNDTTPKSWAKEYVQTSTKKEVKKEETPDEEEEEAPKKKSKKSKKQESSDSDSD
What is the function of this protein?
Plays a central role in ribosomal RNA processing.  Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA.  This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1.  Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs (By similarity).
What are the official names of this protein?
Putative H/ACA ribonucleoprotein complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: CWC22_USTMA
Sequence: MPSRERSPSSGLGFQSDSSRSSPPDAGVTAHKRKRSPTRSVSSRSTSSRSPSRSRSPPPRSRRRRRSSRDRSQSSNSDESTEERKNTTRAREALEQNAKTLEIAAKGEALRSTLAQLSATKSGGAYVPPARLKALMAEAAAADPGSVEYQRMSWDALKKSITGLVNKVAVENIKSIVPELFGGANLIRGRGLYCRSIMRAQALSLSFTPVFAALTAIVNTKLPMIGELLAVRLVSQFRRSFKRNDKAVCNSTAMFLAHLVNQRVVHEVLALEILVLLLEKPTDDSVEIAVGFMREVGAFLTEEAPKANNSIFDRFRAVLYEGEISKRVQYMIEVLSQVRREGFKENPRIPDALDLVEEDDQITHRISLDDQLNIEEGLNVFKMDPEFVENEERYRSIKAEILGENSDSDKTGSEADSESGSSSDDSSDDEAGEGPDDAQRQLEIHDRTETNLINLRRTIYLTIMSSLDFEESVHKLLKLEVPEGQDIELCNMIVECCSQERTYSKFYGNMGERFCKLHRKWADTFAQSFSNYYDTIHRYETNRLRNIARFFGHLFSTDSISWASMSVIHMNEEDTTSSSRIFVKIMFQEMQQQLGLKELAERFKEPSLQENWKGLFPTDNPKSTRFSINYFTSIGLGVLTEEMREYLKNAPKLLLAQRQAALAARGSDNSDSDSSSVLSSSTGSRSRTSYSSYSRSSRSYSSGSGSYSSRSRSSRSYSSRSYSSRSYSSRSRSRSRSRSRSRSRSRSRSRSRSRSRSPSEHQRHGRRRARSASYSSYSSRSRSSSSSSSRSRSRSRSRSRSFSRSLTPRGSYSRSCSRSPVPRRRAPRSRSRSADPRKRSSRRSPSVSSYSGSETDDSISRSPSPRAGYVDRRSHRHSRSASPARR
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
Pre-mRNA-splicing factor CWC22.
What is the protein family that this protein belongs to?
Belongs to the CWC22 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PASI_ECOL6
Sequence: MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTKNKVGIYSRPAKLSDIVHDGDRVEIYRPLIADPKELRRQRAEKSANK
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Unlike the case in E. coli K12 high level expression of this protein abrogates the toxic effects due to overexpression of the cognate toxin PasT.
What are the official names of this protein?
Persistence and stress-resistance antitoxin PasI, Antitoxin PasI, UPF0125 protein PasI.
What is the protein family that this protein belongs to?
Belongs to the UPF0125 (RnfH) family.
Protein: RSMH_HAEIE
Sequence: MNSENSFSSSEHITVLLHEAVNGLALKENGIYIDGTFGRGGHSRFILSQLSSNGRLIAVDRDPRAIAEAHKIQDLRFQIEHNSFSHIPEICDKLNLVGKIDGILLDLGVSSPQLDEAERGFSFMKDGPLDMRMDTTQGLSAEEWLKQVSIEDLTWVLKTFGEERFAKRIATAIVDFNKSAVKNSTEFLSRTSQLAELISQAVPFKDKHKHPATRSFQAIRIFINSELDELESLLNSALDMLAPEGRLSIISFHSLEDRMVKHFMKKQSKGEDIPKGLPLREDQIQRNQKLRIIGKAIQPSDAEIQANPRSRSAILRVAERI
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_ACTP2
Sequence: MKRTFQPSVLKRARTHGFRARMATKNGRQVLARRRAKGRKSLSA
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: FETP_HAEIN
Sequence: MARTVFCEYLKKEAEGLDFQLYPGELGKRIFDSVSKQAWGEWIKKQTMLVNEKKLNMMNAEHRKLLEQEMVNFLFEGKDVHIEGYVPPSN
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: CRCB1_MYCTO
Sequence: MPNHDYRELAAVFAGGALGALARAALSALAIPDPARWPWPTFTVNVVGAFLVGYFTTRLLERLPLSSYRRPLLGTGLCGGLTTFSTMQVETISMIEHGHWGLAAAYSVVSITLGLLAVHLATVLVRRVRIRR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.