PharMolix/UniProtQA huggingface dataset:
Protein: PPIA_FELCA
Sequence: MVNPIVFFDIAVDGEPLGRVSFDLFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTEWLDGKHVVFGMVKEGMNIVEAMERFGSRNGKTSKKITIADCGQI
What is the function of this protein?
Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).  Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity).  Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity).  Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity).  In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity).  Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity).  Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity).  Plays an important role in platelet activation and aggregation (By similarity).  Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity).  Binds heparan sulfate glycosaminoglycans (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase A, PPIase A, Cyclophilin A, Cyclosporin A-binding protein, Rotamase A.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Nucleus. Note=Secretion occurs in response to oxidative stress in vascular smooth muscle through a vesicular secretory pathway that involves actin remodeling and myosin II activation, and mediates ERK1/2 activation.
Protein: ANMK_STRCO
Sequence: MRVIGLMSGTSYDAVEAAAADLELEGEALVMRPLGHLSAPYPDGLRDLIADSLPPAAATVRTVARLDTGIGQAFADVAVRAVRELCGGAAGLVVSHGQTLYHWVEDGAVRGTLQLGQPAWIAEATGLPVVSDLRGRDVAAGGQGAPLVAMTDVLAMAALPGVPAALNLGGIANVTVVAPGAEPLAFDTGPANALMDAAVRHFTGGAAAFDEDGRRAGAGRVDPGLLRVLLDDPYYGRPAPKSTGKEQFHLPYLLAALAAAPVAEPDDVLATLARLTAVTVADACRAHGVTRLVVSGGGARNPVLMGMIAEELPGVDLGSSDALGLPSDAKEALAFALLGFLTVNGLPGAIPSGTGARRASLLGSITPGREPLRLPEPAGEPPRVLRVVGGP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: FLJM_CAUVC
Sequence: MALNSINTNSGALIALQNLNSTNAELTQVQQRINTGKKIGSAKDNGAIWATAKNQSATAGSMNAVKDSLQRGQSTIDVALAAGDTITDLLGKMKEKALAASDTSLNTASFNALKSDFDSLRDQITKAASNAKFNGVSIADGTTTKLSFLANSDGSAFTVTAKTLTLGGLGLTATSSFTTAAAAKTMIGTIDTALQTATNKLASLGTSSTGLDTHLTFVGKLQDSLDAGVGNLVDADLAKESAKLQSLQTKQQLGVQALSIANQSSSSILSLFR
What is the function of this protein?
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
What are the official names of this protein?
Flagellin FljM.
What is the protein family that this protein belongs to?
Belongs to the bacterial flagellin family.
What are the subcellular locations of this protein?
Secreted. Bacterial flagellum.
Protein: TRPB_LISMO
Sequence: MTYQAPDENGFYGKFGGRFVPETLMKAVKELDEAYQASKTDPAFQKELNYYLKEYVGRETPLYFAEQLTAHAGGAKIYLKREDLNHTGAHKINNTIGQALLARQMGKQKVVAETGAGQHGVATATVAALFNMKCTIFMGEEDVKRQSLNVFRMELLGAKVVSVKAGSRTLKDAVNEALRFWVANVEDTHYIMGSVLGPHPFPEIVRDYQSVIGIEARKQHLEKEGKLPDAIVACVGGGSNAMGLFYPFVDDASVQMHGVEAAGHGLETEFHAATISKGEIGILHGAMMDVLQDENGQILEAFSISAGLDYPGIGPEHSFFRDLGRAAYHSVTDDEAVEAFQLLCRTEGIIPALESSHAISYAVKLASKMRPEESMVVCLSGRGDKDVNQLKERLEGQTND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: RL25_ANAPZ
Sequence: MDHEDMIKVDASVRERCGTGSARALRARGLIPAVIYGKNRDPINISLSQVDFLKKCRTFPIFSKLIELCIGEKKEYVITKDIQKHPVSGAIAHVDFQFVDQDAEMKMEVPLVFLNEQKCVGVKRGGVINILHRSLIIRCSPHHIPKSLEVDLIDVAIGHSLHVSDLKLPSTINVVMKEEDPVIATVVASGGGISEDAEEAAPASDIPEAGK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: RRF_DEIRA
Sequence: MADMKSIQADTREKMNKAIEAFENNLSVLRTGRANPGILKKIVVDYYGSQMPIDQVASITTPDPRTLVITPWDRGALNPIEKAIRDSDLGLNPNNKGDTIFISLPMLTEERRKDLVKNAKNYAEDARIAVRNLRKHALDEVKKVEGLGEDEIKRGEADVQKITDEYVARVESVFQKKEQEILG
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUD_PHOPR
Sequence: MLNVMDKFCWLYEKPTCQGQIKALPEHFIVKENLGFEFAGKGEHFMVKIRKVGENTKYVVNELAKACGVKSRDVSWAGLKDRHAVTEQWISVHLPGKADPDLTDFVAEHPGIEVLETTRHDKKLRPGDLVGNWFQIRLLDLTNPEELALKLEQVKMHGVPNYFGQQRFGHGGNNVIKARSWGNDEFRLRDKSKRSFYLSAARSWLFNMVLSTRIEQGSVNSLMVGDCLQNAGEDNCFLAESITEELQASIDKGLVNITAPLVGDNALPTAADAEAFELAIIANEPSLLKLICDNRMRHERRTLLLKPQEMEWQFDGNDVVLSFALPAGCFATSVVRELLVEQEGSTHANIDQ
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RNB_VIBCM
Sequence: MFQDNPLLAQLKQKIQETLPKKEGTIKASDKGFGFLEVDSKTSYFVPPPYMKKCMHGDKVVAFIRTENEREVAEPSELIEQSLTRFIGRVKLFKGKLNVAPDHPQLKKLSLKAKTKKGLNEADFQEGDWVVAHLVRHPLKGDDGFFVQISHKITDANDKIAPWWVTLAENDLPNSEPAGIDDWQLKDDADLVREDLTALPFVTIDGESTKDMDDALYAQQLPNGDFALTIAIADPTAYITPEDEMDKVARERGFTIYLPGRNIPMLPRDLADELCSLMENQVRPALCCSVTIRKDGVIGDDIRFFAANIKSHARLVYDHVSDWLETGSSEQWQPSEEIAQVVRDLYAFSQARANWRETHAVVFPDRPDYRFELSADNDVVAIHADMRRTANRLVEESMITANICAGKTLQTTFGFGVFNTHAGFKAEKMADVVELMAVNGAPNADAETLATVEGFAALRRWLATQETSYLDNRIRKYQSYSEIGNQPLPHFAMGLDVYATWTSPIRKYGDMINHRLLKAHILGKAPVQTPDETVGEELALHRKHHKIAERNVADWLYARTLADEPAKETRFQAEIFDINRPGMRVRLLENGAMAFIPGALILDNKERIECNGEDGTVLIDKEVVYKLGDVLEIVLTEVNQENRSLVGKPTQVFADLVSETQTSAEQPAEGAENNEPQV
What is the function of this protein?
Involved in mRNA degradation.  Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
What are the official names of this protein?
Exoribonuclease 2, Exoribonuclease II, RNase II, Ribonuclease II.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family. RNase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_PSEFS
Sequence: MSRVCQVTGKGPVTGNNISHANNKTRRRFLPNLQHHRFWVEEEKRFVRLRVSAKGMRIIDKRGITVVLAEIRAAGKI
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: GATC_OCEIH
Sequence: MAEISKDQVKHVAHLARLELDDEAVEKMSDELSAIIDFAEQLNELDTDSVEPTTHVLNLKNVMRKDEPKKWISQEDALRNAPDHKDGQIRVPSILE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: DPOL_HBVC2
Sequence: MPLSYQHFRKLLLLDDEAGPLEEELPRLADEGLNRRVAEDLNLGNLNVSIPWTHKVGNFTGLYSSTVPVFNPEWQTPSFPNIHLQEDIINRCQQYVGPLTVNEKRRLKLIMPARFYPNLTKYLPLDKGIKPYYPEHAVNHYFKTRHYLHTLWQAGILYKRETTRSASFCGSPYSWEQELQHGRLVFQTSTRHGDESFCSQSSGILSRSPVGPCVRSQLKQSRLGLQPQQGSLARGKSGRSGSIRARVHPTTRRSFGVEPSGSGHIDNSASSASSCLHQSAVRKTAYSHLSTSKRQSSSGHAVELHNIPPSSARSQSEGPIFSCWWLQFRNSKPCSDYCLSHIVNLLEDWGPCTEHGEHNIRIPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGSTHVSWPKFAVPNLQSLTNLLSSNLSWLSLDVSAAFYHIPLHPAAMPHLLVGSSGLPRYVARLSSTSRNINYQHGTMQDLHDSCSRNLYVSLLLLYKTFGRKLHLYSHPIILGFRKIPMGVGLSPFLLAQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLFTSVTNFLLSLGIHLNPNKTKRWGYSLNFMGYVIGSWGTLPQEHIVLKIKQCFRKLPVNRPIDWKVCQRIVGLLGFAAPFTQCGYPALMPLYACIQSKQAFTFSPTYKAFLCQQYLHLYPVARQRSGLCQVFADATPTGWGLAIGHRRMRGTFVAPLPIHTAELLAACFARSRSGAKLIGTDNSVVLSRKYTSFPWLLGCAANWILRGTSFVYVPSALNPADDPSRGRLGLYRPLLRLPFQPTTGRTSLYAVSPSVPSHLPDRVHFASPLHVAWKPP
What is the function of this protein?
Multifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids.  This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode.  Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid.  Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein.  Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome.  After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA).  The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
What are the official names of this protein?
Protein P.
What is the protein family that this protein belongs to?
Belongs to the hepadnaviridae P protein family.
Protein: GATC_THISH
Sequence: MSLSHDDVRKIAHLARLAVSDADVEAYARSLSSILDFVEQMEAVKTDHVAPMAHPQDTAQRLRDDAVSEADQRERFQSIAPAVEAGLYLVPKVIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: SODF_PSEAE
Sequence: MAFELPPLPYEKNALEPHISAETLEYHHDKHHNTYVVNLNNLIPGTEFEGKSLEEIVKSSSGGIFNNAAQVWNHTFYWNCLSPNGGGQPTGALADAINAAFGSFDKFKEEFTKTSVGTFGSGWGWLVKKADGSLALASTIGAGNPLTSGDTPLLTCDVWEHAYYIDYRNLRPKYVEAFWNLVNWDFVAKNFAA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (Probable).  Partially complements double sodA-sodB deletions in E. coli (PubMed:8244935).
What are the official names of this protein?
Superoxide dismutase [Fe].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: VP8_BTV11
Sequence: MLSGLIQRFEEEKMKHNQDRVEEPSQVRVDDTISQPPRYAPSAPMPSSMPTVALEILDKAMSNTTGATQTQKAEKAAFASYAGVARDDVRLRQIKRHVNEQILPKLKSDLSGLKKKRAIIHTTLLVAAVVALLTSVCTLSSDMSVAFKINGTKTEVPSWFKSLNPMLGVVNLGATFLMMVCAKSERALNQQIDMIKKEVMKKQSYNDAVRMSFTEFSSIPLDGLEMPLT
What is the function of this protein?
Facilitates viral particle release either by increasing plasma membrane permeability through a viroporin-like activity or by viral budding.
What are the official names of this protein?
Non-structural protein P8, Non-structural protein NS3.
What is the protein family that this protein belongs to?
Belongs to the orbivirus NS3 family.
What are the subcellular locations of this protein?
Host cell membrane; Multi-pass membrane protein. Host Golgi apparatus.
Protein: RRF2M_ASPFN
Sequence: MVAAPLLRAHQAARLQSVSTSRLGLNPHVIKSAGRLQLLRGSSFSTATSKWQAGVLDRTRNIGIIAHIDAGKTTTTERMLYYSGFTRRIGDVDEGSTVTDFLPAERARGITIQSAAITFHWPPQTAGDGNTTPQEPQTPRSASSHTVNLIDTPGHADFTFEVMRSLRILDGAVCILDGVAGVEAQTEQVWHQASTYRIPRIVYVNKLDRDGAAFGRTVREVASRLGGWPAVCQIPWFEGGNGRFTGIADAINLQGLRWEEGDGKSVKMFNLEQLASEEPQLAQELKRARVALVELLSEHDEAMVEKFFDCEEDHLAVPPNDILESLRRCLLEEQGRKIIPIFAGASFRNIGVQPLLDAVTNLLPSPPETPEPEVSIGGVKGGLRRLLSGDLLVEQGEKAASAKGKHKKKSAIQAESRNAIEKLQGCALAFKVVNDPKRGVLVYVRVYSGSLDRNSILYNTNLNVSERAPRLLKMYANDAVEVDSIPEGHIGVVAGLKHTRTGDTLVTYSGNKATPPEPLNTLQLRPITVPPPVFFASVEPHSLSEEKRLQESLAMLLREDPSLHVTVDEDSGQTLLSGMGELHLEIARDRLLNDLKAKASMGRIEIGYRECPLGASGPITKIFDKEIAGRKGKAGCTATVEPFDPEETTTEPDPSTLSIQTTDGNQIIIQAPGLEVEVNKKGIEESPLLPPGLDVHALRTALQNGCLAALARGPQFTFPMHGTRVTLTFNPAEHLFGNESTPSALSAAARLATSSALRDLPSGAGTSLMEPVMNVIISVDEASLGAVVHDISSSRGGHIISLDEETPLQTTGITSNPTDDLLPPIDPNKVYAPPDPFQSSTVGIDLPSSANRPRTITAKVPLKEMVGYLKHLRSLSAGRGTFVMSVDRFEKMSAPRQKAVLAELRGDFF
What is the function of this protein?
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.  Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
What are the official names of this protein?
Ribosome-releasing factor 2, mitochondrial, RRF2mt, Elongation factor G 2, mitochondrial, EF-G2mt, mEF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: GMHA_SALPK
Sequence: MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVSNDFGYDYIFSRYVEAVGREGDVLLGISTSGNSGNVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEIRVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROB_BURPS
Sequence: MITVNVDLGERAYPIHIGADLIGRTELFAPHIAGASVTIVTNTTVEPLYGDTLRAALAPLGKRVSTVVLPDGEAYKNWETLNLIFDGLLEQHADRKTTLIALGGGVIGDMTGFAAACYMRGVPFIQVPTTLLSQVDSSVGGKTGINHPLGKNMIGAFYQPQAVIADIGALSTLPDRELAAGVAEIVKTGAIADAAFFDWIEANVGALTRRDPDALAHAVKRSCEIKAGVVAADEREGGLRAILNFGHTFGHAIEAGLGYGEWLHGEAVGCGMVMAADLSVRTGHLDEASRARLCRVVEAAHLPTRAPDLGDARYVELMRVDKKAEAGAIKFILLKRFGETIITPAPDDAVLATLAATTR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GRPE_SHEDO
Sequence: MSTEPTNQDQAPIDEALTQEVAQDEASLMDELTQANFRVEELEQLLAESQAALAERKDVEMRAAAETQNIRTRAAKDVEQARKFALEKFANELLPVIDNMERALQGTNPEDEATKAIYEGVELTMKGFLTSVEKFGVKQVNPQGETFNPDHHQAIGMQPSPDFPANTVMMVMQKGYLLNDRLLRPAMVMVSQGGPSVDIEA
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_ALKOO
Sequence: MPTINQLVRKGRYVEEYKSTAPALQKGMNTLRKKATDISAPQKRGVCTSVKTVTPKKPNSALRKVARVRLTNGIEVTAYIPGIGHNLQEHSVVLIRGGRVKDLPGVRYHIVRGALDTAGVANRQQSRSKYGAKKPKAAKK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MURD_PARP8
Sequence: MFGEKFRDRQKPMVLVLGLGESGLAMARWCARHGCRLRIADTREVPPNLSALEAHGIEGNFVGGPFSEVLLEGVELVAISPGLSPLAADLVPLIATARERGIPVWGELEFFAQALKTLGESGYAPKVIAITGTNGKTTTTSLTGLLCERAGKKVAVAGNISPAALDKLTEAIDNTALPDVWVLELSSFQLETAHTFEPDAAVILNITQDHLDWHGGLDAYAAAKGKIFGKNTVRVLNRDDARVMTLASSEQSGAQLVTFGVNEPVRDGDYGLLRDNGMIWLVQAQDRDATDEPAPTRRRKSESTAPPDIGLKRLMPADALRIRGLHNATNALAAFALARAIGLPGAPLLHGLREYRGEPHRVELIASIEGVDYVDDSKGTNVGATVAALDGLAQRVVLIAGGDGKGQAFDPLAEPVTRWCRCVMLIGRDAPQIRAALEHTGIAITDHATLEEATRAASAVAQPGDAVLLSPACASFDMFKGYAHRAAVFRSTVEDIAAGRGTMI
What is the function of this protein?
Cell wall formation.  Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
What are the official names of this protein?
UDP-N-acetylmuramoylalanine--D-glutamate ligase, D-glutamic acid-adding enzyme, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_LEIXX
Sequence: MRSGVRLGIDVGTVRIGVSCSDLHGTLATPYETVARSGDAADRRRIAEIVTDLGVVEIIVGLPLALSGVHTASTADAVAFAEALVVEVGAPVRLVDERLSTVSAHSALRSSGKNAKSSRPVVDQAAATIILQHALDAERATSRPPGHPVEPRIGP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACTP_SALTY
Sequence: MKRVLTALAAALPFAAHAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFTEAMAVHPKGTAIMSPGGLVQDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPAYKDAAGALIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFRKGATEREELKVSKITVLVLGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMLGGWLGLLTAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGNREREQFRAQFIRSQTGFGVQQGRAH
What is the function of this protein?
Transports acetate.
What are the official names of this protein?
Cation/acetate symporter ActP, Acetate permease, Acetate transporter ActP.
What is the protein family that this protein belongs to?
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENO2_METCA
Sequence: MSKIVDILAREILDSRGNPTVQAEVILDSGAEGSAMVPSGASTGAREAIELRDGDASRYGGKGVLKAVENVRGPIKAALTGMDAADQAAIDRRLIELDGSDNKGVLGANAILAVSLATAHAAAADAKKPLYAYLNRSGEFLLPVPMMNIINGGAHADNSIDMQEFMILPVGAPSFREALRYGAEVFHALKKVLSDRGLATGVGDEGGFAPNLPSNEAAIGIILEAIEKAGYRPGEDICLGLDVASSEFYSDGIYTLASEGRRFTSEEFSDHLAAWVDKYPIVSIEDGMAENDWHGWGIHTDRLGRRIQLVGDDLFVTNPAILKQGIEARIANSILIKVNQIGTLTETLEAIHIARKAGYTSVVSHRSGETEGTTIADIAVATCTGQIKTGSLSRSDRIAKYNRLLKIEEELGDKARYGGRGAVKNLA
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase 2, 2-phospho-D-glycerate hydro-lyase 2, 2-phosphoglycerate dehydratase 2.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: SFTA_BACSU
Sequence: MSWLHKFFDLFLGESEEDAERETKPAQIPQQQEVHHPEGQLKRLEDPKIYYEYPKGKFRFPVVPDGYKNHDLRRRRTPSDEPKSAPRPSAAPYRERPRNEEEQHTYQAAEPAKKPFKPTNIPSPVYGFNQKPSVKKDVPKKPSETLNEPDKSVKEKVTLLSEEIERERGYPASDTQAHSKIESPFFPDTQFEKQPSGVLNRKDTEHDEALAKRPAEPSGNKVPFESGVQQPEKEEPFFPAEQAEEQTPPEMLTDTAAEGLSDSEVGREEPATAEEEQREQQPEKFEEPVFSAELDEEQTAPESQTEAVSEDEKAKEPSDSPVYNHHENAAEGAESPFVQEEQMDIRQEEPLFTDHEYSSEALAQAETVAKESEEPSESIINNHYDTLGEAQETKIDVQPDSHTELEKTEHMEQGSKSSTATLENRQEIRADKPREASEEPKKRPGVQEKRTEQSASSQKGPSVPFNVMMLKRDTHKQQKAEERRGSYVFPNVALLDVPPAQVQDDTAWIEEQRQLLDLTLKNFNVRANVVHVTQGPSVTRFEVHPEPGVKVNKITNLSDDIKLSLSAKDIRIEAPIPGKNTIGIEVPNRTSKVVDLRQMIRSSAFRTSKSPLTAALGLDISGNPVVIDLKKMPHGLIAGATGSGKSVCINTILVSLLYKADPSEVKVLLIDPKMVELAPYNKIPHLVSPVITDAKAATAALKWVVEEMERRYELFAHSGVRDIDRFNQLTAEHQMGEKLPYLVVIIDELADLMMVAPNDVEESIARIAQKARACGIHLLVATQRPSVDVITGLIKANIPTRIAFSVSSQVDSRTIIDIAGAEKLLGKGDMLFLENGSGKPVRLQGNFVSDREIDRVVSHVRSQMPPTYLFEQEELVRQGSALKEEDELFYEACEFVVEQNSASTSSLQRRFRIGYNRAARLIDMMEAEGMISEAKGSKPREVLITASDLINE
What is the function of this protein?
Required for the accurate completion of chromosome partitioning, in part by promoting efficient resolution of chromosome dimers, before the formation of the division septum.  Binds to DNA in a non-specific manner.  Shows ATPase activity.  Not required for cytokinesis.
What are the official names of this protein?
DNA translocase SftA, Septum-associated FtsK-like translocase of DNA.
What is the protein family that this protein belongs to?
Belongs to the FtsK/SpoIIIE/SftA family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Colocalizes with FtsZ at nascent division sites.