PharMolix/UniProtQA huggingface dataset:
Protein: TKT1_VIBVY
Sequence: MPSRKHLANAIRALSMDGVQKANSGHPGAPMGMADIAEVLWRGHLNHNPSNPEWADRDRFVLSNGHGSMLIYSLLHLSGYELSIDDLKNFRQLHSKTPGHPEYGYAPGIETTTGPLGQGITNAVGMAMAEKALAAQFNKEGHDIVDHFTYVFMGDGCLMEGISHEACSLAGTLGLGKLIAFWDDNGISIDGHVEGWFSDDTPKRFEAYGWHVIPAVDGHNAEAINAAIEAAKADPRPTLICTKTIIGFGSPNKSGSHDCHGAPLGAEEIAAAREFLGWEHPAFEIPADVYAEWDAKAAGAAKEAAWNAKFDAYAAAYPAEAAEFKRRVNGELPAQWEEKANQIIADLQANPANIASRKASQNALEAFGKMLPEFMGGSADLAPSNLTMWSGSKSLEASDFSGNYIHYGVREFGMTAIMNGIALHGGFVPYGATFLMFMEYARNAMRMAALMKVQNIQVYTHDSIGLGEDGPTHQPVEQIASLRLTPNMSTWRPCDQVESAVAWKLAIERKDGPSALIFSRQNLAQQPRSAEQVADIAKGGYILKDSDGKPELILIATGSEVELAVKAAEQLTAEGKKVRVVSMPATDAFDKQDAAYRESVLPSDVTARIAIEAGIADFWYKYVGFDGRIIGMTTFGESAPADQLFEMFGFTVENVVNTAKELLA
What is the function of this protein?
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
What are the official names of this protein?
Transketolase 1, TK 1.
What is the protein family that this protein belongs to?
Belongs to the transketolase family.
Protein: COXX_NOCFA
Sequence: MLADRFTGSGLPSRLMRRVLAYIALTKPRVIELLLVATIPTMLLADRGHIDIRLILATLFGGWMGAASANTLNCVADADIDKVMKRTAKRPLARDAVPTRNAFVFGVVLGLASFAWLWWQANLLSGALVVATILFYVFVYTLGLKRRTSQNVVWGGAAGCMPALVGWSAVTGTIGWPALALFGVIFFWTPPHTWALAMRYKEDYRAAGVPMLPVVATERTVTKQIVIYTWLTVLTTLALVPATGVIYAAVALVAGAWFLLMAHQLYAGVRRGESVKPLRLFLQSNNYLAVVFCGLAVDSVLGWDTIGSFFG
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LDHB_ANAPL
Sequence: MATLKEKLMTPVAAASAVPSSKITVVGVGQVGMACAVSILGKGLCDELALVDVLEDKLKGEMMDLQHGSLFLQTHKIVADKDYAVTANSKIVVVTAGVRQQEGESRLNLVQRNVGVFKGIIPQIVKYSPNCTILVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDTARFRYLMAERLGIHPTSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPAMGTDKDSENWKEVHKQVVESAYEVIRLKGYTNWAIGLSVAELCETMLKNLCRVHSVSTLVKGTYGIENDVFLSLPCVLSASGLTSVINQKLKDDEVAQLKKSADTLWSIQKDLKDM
What is the function of this protein?
Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+).
What are the official names of this protein?
L-lactate dehydrogenase B chain, LDH-B, Epsilon-crystallin.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_LEPIN
Sequence: MSDIFRFDTEEQTLTKEKIKLKKPSKYRVIILNDDFTPMEFVVWILQMVFHRSRAESQQIMLKAHITGKALCGVYSHDVARTKVAQVQQLAEQHGYPLHCTMEVEEGEEES
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: ATL4_RAT
Sequence: MELWLGRLWLYVMLLLLLLQLCQDQELLGPSLQTPSEEDQVPEGLWGPWGRWASCSQPCGVGVQRRSRTCELHPALSLPPRPPRHPEAPQPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPGMFGYGRVPFALPLHRSRRLAHKPGQPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRTSSAPSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQLSRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTPECSGESEQMRACSQEPCPPEQPDPRALQCAAFDSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGSLDICVAGHCLSPGCDGILGSGRRPDGCGVCGGDGSTCRLVSGNLTDRGGPLGYQKILWIPAGASHLRISQFRPSSNYLALRGPGGRSIINGNWAVDPPGSYAAVGTVFQYNRPPREEGKGETLSAEGPTTQPVDVYMIFQEDNPGVFYQYVTSAAPESPSTMPPALQLQPEMLRGEPLLPSAPRPVRAPGTLQRQARIPQVPPPTHVRTAMGSSAGYWKQVGHSECSASCGKGVWRPIFLCVSRESGEELDEQSCAVGARPPASPESCHRPPCPPYWEAGEWTSCSRSCGPGTQHRQLLCRQEFGGGGSSVPPERCGHLPRPNITQSCQLRLCGHWEISSPWSQCSVRCGRGQRSRQVRCVGSNGHEVGKQECASGPPPPPSREACDMGPCTTAWFYSDWSSKCSAECGTGIQRRAVVCLRSGETLQGDPEAGSTEQGCPLRSRPPDMRACSLGPCEKTWRWYTGPWSECSSECGSGTQHRDIICVSKLGTKFNVTSPSNCSHLPRPPALQPCQGQACEDQWFSTLWSPCSQSCQGGVQTREVQCLSSNHTLSSRCPPHLRPSRKRPCNSQPCNQRPDDQCKDSSPHCPLVVQARLCVYPYYTATCCRSCAHVLEQSQLEPA
What is the function of this protein?
Positive regulation of apoptosis.  May facilitate FBN1 microfibril biogenesis (By similarity).
What are the official names of this protein?
ADAMTS-like protein 4, ADAMTSL-4.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Colocalizes with FMN1 microfibrils in the eye ECM.
Protein: PETD_POPAL
Sequence: MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTVVALWLGIGATLPIDKSLTLGLFQIDSI
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 4, 17 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family. PetD subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CAT_CLOBU
Sequence: MNFNLIDINHWSRKPYFEHYLNNVKCTYSMTANIEITDLLYEIKLKNIKFYPTLIYMIATVVNNHKEFRICFDHKGSLGYWDSMNPSYTIFHKENETFSSIWTEYNKSFLRFYSDYLDDIKNYGNIMKFTPKSNEPDNTFSVSSIPWVSFTGFNLNVYNEGTYLIPIFTAGKYFKQENKIFIPISIQVHHAICDGYHASRFINEMQELAFSFQEWLENK
What is the function of this protein?
This enzyme is an effector of chloramphenicol resistance in bacteria.
What are the official names of this protein?
Chloramphenicol acetyltransferase, CAT.
What is the protein family that this protein belongs to?
Belongs to the chloramphenicol acetyltransferase family.
Protein: SYS_CHLMU
Sequence: MLDIRLIRKEPKECEARLQKKDPSISLERLLDLDKNVRQLKADSESLLARRKALSGQIHKAKVANEDATPLIQGVNAIADQLVAFEKTLQEQEALLLDLMARLPNYPDEDVPVSPDKSGNKIIKSHGEIPTFTFPPKHHVQLNEKLQILDFKLPAKTSGSGWPAYKNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYYRVEDGEQSLFLIPTAEVVLNGFHSQEILNEQDLPLYYAAFTPCFRREAGAGGSHERGLVRVHQFHKVEMFAFTTPEQEEIAYQKMIGIVEEILSELQLPYQLSLLSTGDMSFTAKKTIDAEVWLPGQQAFYEVSSISKCGDFQSRRSETRYRDAQGKLHFVNTLNGSGLATPRLLVAILENYQQEDGSVVIPHALRPYMNNQEILLPKTDR
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBA_PSINU
Sequence: MTATLERRESASLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLASIEAPLVNG
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.
What are the official names of this protein?
Photosystem II protein D1, PSII D1 protein, Photosystem II Q(B) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: INSL5_PANTR
Sequence: MKGSIFTLFLFSVLLAISEVRSKESVRLCGLEYIRTVIYICASSRWRRHLEGIPQAQQAETGNSFQLPHKREFSEENPAQNLPKVDASGEDRLWGGQMPTEELWKSKKHSVMSRQDLQTLCCTDGCSMTDLSALC
What is the function of this protein?
May have a role in gut contractility or in thymic development and regulation.  Activates RXFP4 with high potency and appears to be the endogenous ligand for this receptor (By similarity).
What are the official names of this protein?
Insulin-like peptide INSL5, Insulin-like peptide 5.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: VATL2_YEAST
Sequence: MSTQLASNIYAPLYAPFFGFAGCAAAMVLSCLGAAIGTAKSGIGIAGIGTFKPELIMKSLIPVVMSGILAIYGLVVAVLIAGNLSPTEDYTLFNGFMHLSCGLCVGFACLSSGYAIGMVGDVGVRKYMHQPRLFVGIVLILIFSEVLGLYGMIVALILNTRGSE
What is the function of this protein?
Proton-conducting pore forming subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:1837023, PubMed:9030535).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:1837023, PubMed:9030535).
What are the official names of this protein?
V-type proton ATPase subunit c', V-ATPase subunit c', Proteolipid protein VMA11, Trifluoperazine resistance protein 3, V-ATPase 16 kDa proteolipid subunit 2, Vacuolar proton pump c' subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: ATPB_CYTH3
Sequence: MANIGKITQIIGPVVDVGFEGEYALPQILDALEVTRPDGQKVILECQQHLGEDRVRTIAMDSTDGLTRGMEVKTYGMPISMPVGEDIRGRLYNVVGDAIDGIPSGVAANRMSIHRQAPKFEDLSTNTEVLFTGIKVIDLLEPYVKGGKIGLFGGAGVGKTVLIMELINNIAKAYAGLSVFAGVGERTREGNDLLREMIESNVIRYGDEFKHSMEKGEWDLSKVDATELLKSQATLVFGQMNEPPGARARVALAGLTVAEYFRDGDGQGQGRDILFFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTKRGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLNRKISELGIYPAVDPLDSTSRILSPEILGSEHYDCAQRVKEILQRYKELQDIIAILGMDELSEEDKQAVHRARRVQRFLSQPFHVAEQFTGLKGELVNIKDTIKGFNMIMDGALDHLPEAAFNLVGSIEQAIAKGEKLVADSKK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SRTXD_ATREN
Sequence: CTCKDMTDKECLYFCHQDIIW
What is the function of this protein?
Vasoconstrictor activity.  These toxins cause cardiac arrest probably as a result of coronary vasospasm.  May act by displaying agonistic activities towards endothelin-1 and -2 receptors (EDNRA and EDNRB).
What are the official names of this protein?
Sarafotoxin-D, SRTX-D, S6D.
What is the protein family that this protein belongs to?
Belongs to the endothelin/sarafotoxin family.
What are the subcellular locations of this protein?
Secreted.
Protein: ACCD_DINSH
Sequence: MNWISNYVRPTINSLFSRREVPENLWRKCPECGTMLFHRELSDNLFVCISCDHHMAITPRQRFEALFDGGVFSEVKVPAPIADPLQFKDQKKYPERMKSAVKATGEPEAMLVAEGEIGRTPIVAAAQDFSFMGGSMGMYVGNAIIAAAERAVALKRPLILFSAAGGARMQEGILSLMQMPRTTVAVQMLKEAGLPYIVVLTHPTTGGVTASYAMLGDVQIAEPNALICFAGPRVIEQTIREKLPEGFQRAEYLLDHGMLDRVTHRMKLRDELIRITRMLLGLGPAIVGDLPAPDPAPATPEPQKAAPSAPAQDKPGAGRS
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_BIFLS
Sequence: MANIKSQKKRVLTNEKAHLRNVAVKSGLKTAIRATREAIAAGDKAAAEAAYKVAAQKLDKAAGAGVIHRNQAANRKSGLAVAINAL
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: L_MABVM
Sequence: MQHPTQYPDARLSSPIILDQCDLLARSLGLYSHYSHNPKLRNCRIPHHIYRLRNSTALKTFLQNCSILTVPFHSIWDHILTSIQYDAINHVDDFKYLLPSELVKYANWDNEFLKAYLNKILGLDHVFSASARSQCEDFSPKENPYYWGMLLLVHLSQLARRIKGQRGSLRSNWKFIGTDLELFGIADFVIFKVPVKTIIRNAVSLQASKPGLRIWYRDQNLTPYLCDDEFIVSVASYECFIMIKDVFIERYNTWEICARAWLEDSDGADYPPLDVLGELYNQGDQIIAMYLEDGFKLIKHLEPLCVSCIQTHGIFTPRKYWFQSQMIKSYYDELHDLNLKLQISDNKAECAQNFIKTIVQAKLTPQQYCELFSLQKHWGHPVLYNDVALDKVKKHAQSTKILKPKVMFETFCVFKFIVAKNHYHSQGSWYKTTHDLHLTPYLRQHIVSNSFPSQAEIYQHLWEWYFVEHEPLFSTKIISDLSIFIKDRLTAVNQECWDSVFDRSVLGYNPPVRFQSKRVPEQFLGQADFSLNQILEFAEKLEYLAPSYRNFSFSLKEKELNIGRTFGKLPYRVRNVQTLAEALLADGLAKAFPSNMMVVTEREQKEALLHQASWHHNSASIGENAIVRGASFVTDLEKYNLAFRYEFTRHFIDYCNRCYGVKNLFDWMHFLIPLCYMHVSDFYSPPHCVTEDNRNNPPDCANAYHYHLGGIEGLQQKLWTCISCAQITLVELKTKLKLKSSVMGDNQCITTLSLFPIDAPNDYQENEAELNAARVAVELAITTGYSGIFLKPEETFVHSGFIYFGKKQYLNGVQLPQSLKTMARCGPLSDSIFDDLQGSLASIGTSFERGTSETRHIFPSRWIASFHSMLAINLLNQNHLGFPLGFNIDISCFKKPLTFSEKLIALITPQVLGGLSFLNPEKLFYRNISDPLTSGLFQLKNALEFLEKEELFYILISKKPGLADASDFVMNPLGLNVPRSKEIITFLRQTVRENITITSQNRIINSLFHIGSDLEDQRVCEWLLSSNPVMSRFAADIFSRTPSGKRLQVLGYLEGTRTLLASRTISLTTEGTMLMKLRELTRNRWKSWFSYIDALDDDLSESLEKFTCTVDVANFLRAYSWSDVLKGKRLIGATLPCLLEQFEVKWINLSEDLREQFNLSSDSKSTINLLPYDCKELRLEGSNDTELNYVSCALDRKVVQKHPSVNRLAWTIGNRAPYIGSRTEDKIGYPPLRVNCPSAALKEAIEMVSRLLWVTQGTADREKLLIPLLNSRVNLDYQTVLNFLPTHYSGNIVHRYNDQYGQHSFMANRMSNTSTRAIISTNTLGKYAGGGQAAIDSNIIFQNTINLGVAVLDIALSLAKLSSASNVTFRLMLNKCCTRHVPSEYLYFDKPLDVDLNKYMDNELVYDNDPLCSGIKGRLGRVSRSTLSLSLNVSDIGSYDFPTIAAWTLGETIVGSIFSDESSQSTDPISSGCTKTFVTHFLVYPVESIFYAFGANLIVESLSLSRIKSIKNLSDLTFLISSTIRNLSHRSLRILQSTFRHELVLTRLAHHIPLISLMLGGSAGEKSSSDAVRLFLTASYQNFINNFSCLMKKGQSSLPVWLYFPSEGQQLKPILKILQRLSDLLSPDKIQKRKILADTCCPIGSFWVYPSKSTRTNHYYASLNYWRDKANKVKNTPFSHLINCSFPEFSSHTSSVSSNQQVTNSKYIVYPENITEINARTRLINYGSTALQGMDTKMPLSEQNLVENCRPSEGIRFKDNQKITKHDQRCEREESSPQQMFPEDNMQTPAHIHSSSPFQILIKSLDAHEDFDASKIILNSEINNLNLTEYTLNTKLLTTPTRTEILDTSPLQSSRYSSTSRERSLLSREQASYLYVDCSNIPSISLDPGFRSMSDQNQVQMLINTYKRDLHACFDSNQFCRFTGVVSSMHYKLYDLLPPGKLKKAICLAEGEGSGARLLLKWKETDYLFFNTLATDSQQEAEILSGRVIPRMLYNIDRLSALLESRRLILNNLTIQITDITNPLWLDSVIQYLPEDSDILTMDAETTKDETREQLYKTIVNIWTRTSPNIPKISIIKVFLLDYEGTLFLMKNAIQYYGQVQLKKPYSSNAKNSEWYLCCGKRRIQRLQIDFSDQVGIFLICKAMSRQRQAIPYWLKHIEKNYPASLHEFFLTLGFPSLESSFCHRYTIPFSEGKALFHKVQSYVRQGKQHLHSLMLDYENNSPLLDLRNHFICSLRGKITKYYNDILKLNLVIKAVEKGKNWSQLVEILPNMHSVCIVHVDHECSGCEKRLLLKLDFIRNTKIAEQKLLNRVIGYILFFPFGLFKSGSLRA
What is the function of this protein?
RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA.  The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N).  The replicase mode is dependent on intracellular N protein concentration.  In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
What are the official names of this protein?
RNA-directed RNA polymerase L, Protein L, Large structural protein, Replicase, Transcriptase.
What are the subcellular locations of this protein?
Host cytoplasm. Virion.
Protein: ALG3_ARATH
Sequence: MAGASSPASLRASRSRRLGKETNRSDLFKKPAVPFAFALILADAILVALIIAYVPYTKIDWDAYMSQVSGFLGGERDYGNLKGDTGPLVYPAGFLYVYSAVQNLTGGEVYPAQILFGVLYIVNLGIVLIIYVKTDVVPWWALSLLCLSKRIHSIFVLRLFNDCFAMTLLHASMALFLYRKWHLGMLVFSGAVSVKMNVLLYAPTLLLLLLKAMNIIGVVSALAGAALVQILVGLPFLITYPVSYIANAFDLGRVFIHFWSVNFKFVPERVFVSKEFAVCLLIAHLFLLVAFANYKWCKHEGGIIGFMRSRHFFLTLPSSLSFSDVSASRIITKEHVVTAMFVGNFIGIVFARSLHYQFYSWYFYSLPYLLWRTPFPTWLRLIMFLGIELCWNVYPSTPSSSGLLLCLHLIILVGLWLAPSVDPYQLKEHPKSQIHKKA
What is the function of this protein?
Required for N-linked oligosaccharide assembly.  Adds the sixth mannose residue in an alpha-1,3 linkage onto the dolichol-PP-oligosaccharide precursor dolichol-PP-Man(5)GlcNAc(2).
What are the official names of this protein?
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, Alpha-1,3-mannosyltransferase ALG3, Asparagine-linked glycosylation protein 3, AtALG3, Not56-like protein.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 58 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: Y3839_XANOR
Sequence: MPAARQQRGAGVEAAARALLEQAGLRLVVGNANYRGGELDLVMRDGQSLVFVEVRYRRDDRFGGGAASVDWRKRRKLVLAAQLFLGAHPALAALPCRFDVVDASGEPPVLHWIRDAFRADDC
What are the official names of this protein?
UPF0102 protein XOO3839.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: UCRIA_NOSS1
Sequence: MAQFSESVDVPDMGRRQFMNLLTFGTVTGVALGALYPVVNYFIPPAAGGAGGGTTAKDELGNDVSVSKFLESHNVGDRTLVQGLKGDPTYIVVESKEAITDYGINAVCTHLGCVVPWNAAENKFKCPCHGSQYDATGKVVRGPAPKSLALSHAKTENDKIVLTSWTETDFRTGEEPWWS
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex iron-sulfur subunit 1, Plastohydroquinone:plastocyanin oxidoreductase iron-sulfur protein 1, ISP 1, RISP 1, Rieske iron-sulfur protein 1.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein. Note=The transmembrane helix obliquely spans the membrane in one monomer, and its extrinsic C-terminal domain is part of the other monomer.
Protein: ILVC_ECOBW
Sequence: MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNGQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: MMP12_HUMAN
Sequence: MKFLLILLLQATASGALPLNSSTSLEKNNVLFGERYLEKFYGLEINKLPVTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPDVHHFREMPGGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTTVGNKIFFFKDRFFWLKVSERPKTSVNLISSLWPTLPSGIEAAYEIEARNQVFLFKDDKYWLISNLRPEPNYPKSIHSFGFPNFVKKIDAAVFNPRFYRTYFFVDNQYWRYDERRQMMDPGYPKLITKNFQGIGPKIDAVFYSKNKYYYFFQGSNQFEYDFLLQRITKTLKSNSWFGC
What is the function of this protein?
May be involved in tissue injury and remodeling.  Has significant elastolytic activity.  Can accept large and small amino acids at the P1' site, but has a preference for leucine.  Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.
What are the official names of this protein?
Macrophage metalloelastase, MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ARL1_BOVIN
Sequence: MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSEMANSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ
What is the function of this protein?
GTP-binding protein.  Can activate phospholipase D with very low efficiency.  Important for normal function of the Golgi apparatus (By similarity).
What are the official names of this protein?
ADP-ribosylation factor-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Membrane; Lipid-anchor.
Protein: INT11_HUMAN
Sequence: MPEIRVTPLGAGQDVGRSCILVSIAGKNVMLDCGMHMGFNDDRRFPDFSYITQNGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICPILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVLGAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCRERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKANHYYKLFIPWTNQKIRKTFVQRNMFEFKHIKAFDRAFADNPGPMVVFATPGMLHAGQSLQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQVLEVKMQVEYMSFSAHADAKGIMQLVGQAEPESVLLVHGEAKKMEFLKQKIEQELRVNCYMPANGETVTLPTSPSIPVGISLGLLKREMAQGLLPEAKKPRLLHGTLIMKDSNFRLVSSEQALKELGLAEHQLRFTCRVHLHDTRKEQETALRVYSHLKSVLKDHCVQHLPDGSVTVESVLLQAAAPSEDPGTKVLLVSWTYQDEELGSFLTSLLKKGLPQAPS
What is the function of this protein?
Catalytic component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.  Mediates the snRNAs 3' cleavage.  Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).
What are the official names of this protein?
Integrator complex subunit 11, Int11, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, RC-68.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: DEOB_LISW6
Sequence: MPDKFKRVHVVVMDSVGIGEAPDAAKFGDFDVDTFGHIAKHVGGLNMPEMGKLGLSNIREIDGIKKAEKPLAYYTKMQEASNGKDTMTGHWEIMGLYIDTPFRVFPDGFPDDLINQIEEKTGRKVIGNKPASGTEIMAELGEEHVKTGALIVYTSADSVLQIAAHEDVVPLEELYEICEFCREITLDDPYMLGRIIARPFVGEPGAFVRTPNRHDYALKPFKPTVMDALKDGGKDVIAIGKISDIFDGEGVTESIRTKSNMDGMDQFIAVLDKDFNGMSFLNLVDFDALFGHRRDPQGYADALVDFDGRLVEVMEKLTEDDLLIITADHGNDPTYTGTDHTREFVPLLVYSPRFKNGGSELELRKTFADLGATVADNFDVKMPEYGKSFLKDLK
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.