PharMolix/UniProtQA huggingface dataset:
Protein: PCRC_DECAR
Sequence: MIKILALATLLISGFLPGVTVAQQAEYLGFRACTKCHDSQGETWRASAHAKAFDSLKPNAKSEAKTKAKLDPKKDYTQDKNCVGCHVTGYGEPGGFVSGASLDDMKTLVGVTCESCHGAGGKFRNLHGEASDRLKNQGETSERKQLVTAGQNFDMEKACARCHLNFEGSTKHDAKAPFTPFSPSVGSKYQFDFQKSVMTTGAGNPIHTHFKLRGVFKGDPVPAVRAKLQEDAPEPE
What is the function of this protein?
Component of the perchlorate reductase that catalyzes the reduction of perchlorate to chlorite and allows anaerobic growth on perchlorate as the sole electron acceptor.  The gamma subunit may be responsible for electron transfer to the beta subunit PcrB (Probable).
What are the official names of this protein?
Perchlorate reductase subunit gamma, Perchlorate reductase heme subunit.
What are the subcellular locations of this protein?
Periplasm.
Protein: DNAJ_HYPNA
Sequence: MSKRDYYEVLGVERGVDEKALKSAYRKLAMKYHPDQNAGDTAAEDKFKEVGEAYAILSDPQKRAAYDRYGHGAFENGGMGGGSPFGGQGGNPEDIFQDLFSQVFGAGGFAGGRRRSGPQRGADLRYDLEITLEEAFYGKDETIHVPQAVACRPCEGTGAAPGTKPETCETCGGHGRVRAQQGFFTMERTCHICQGRGQIIRKPCKTCGGHGQVKEERKLQVKIPAGVESGMRIRLSGEGEPGTSGGPKGDLYIFVEVVEHDIFERDGPNLYCRAPVPMTTAALGGEIDIPTIDGGRARVAIPEGAQTGRKLRLRSKGMPSVRANGQTGDLYVEMFVETPQNLTARQKDLLRQFCDCSGADCHPESEGFLGKIKRFWGGEGDEKRPV
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RD21L_AILME
Sequence: MFYTHVLMSKRGPLAKIWLAAHWEKKLTKAHVFECNLEITIEKILSSKVKIALRTSGHLLLGVVRIYNRKAKYLLADCNEALLKMKMTFRPGLVDLPKENFEAAYNAITLPEEFHDFDTQNVNAIDVSEHFTQNQSKPEEITLREDYSNDLLFQAGSFGEETEILRRHSFFDDNILLNSSGPLVEHSSGSIAGEKPLFYDSEDGFGDEGAAGEMIDNLLQDDQNILLEDSHLNREISLPPEPPDTIVVEPDNPEYIRLPENGKMDETLSNEEEGFTLDPIDVSDIAEKRKAKKRKLLIDPIKEISSKIMHKQLTSFMDTLMVLELAPPTQRLMMWKKKGGVDTLLSTAAQDLTHAELKMLFTKCFLSSGFKFGRKLMQKESVREEVGSKNIVETSVMEELNFQQDLNQSKTWKDVIDGSKCSSHEDINKNINSEQDIVEMVSSGTEESSSMNAILAQEIENCTVELESSGNEQNIETERWNRRILQTLNSLRESNKMGMQYFSLMKLCRNSDRKQAAAKFYSFLVLKKQQAIELSQSDPYADIIATVGPMFYKM
What is the function of this protein?
Meiosis-specific component of some cohesin complex required during the initial steps of prophase I in male meiosis.  Probably required during early meiosis in males for separation of sister chromatids and homologous chromosomes.  Replaces RAD21 in premeiotic S phase (during early stages of prophase I), while RAD21 reappears in later stages of prophase I.  Involved in synaptonemal complex assembly, synapsis initiation and crossover recombination between homologous chromosomes during prophase I (By similarity).
What are the official names of this protein?
Double-strand-break repair protein rad21-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the rad21 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=In meiotic chromosomes, localized along axial elements in early meiosis: detectable on the axial elements in leptotene, and stays on the axial/lateral elements until mid pachytene. It then disappears and is replaced with RAD21. Compared to REC8, has mutually exclusive loading sites on the chromosomes: REC8 and RAD21L form distinct cohesin-enriched domains along the axial elements.
Protein: HSLO_STRSV
Sequence: MDKIIKTISENGSFRAYVLDSTETVRTAQEKHQTQASSTVALGRTLIASQILAANEKGQTKITVKVLGTSSLGAIITVADTEGNVKGYVQNPGVDIKKTATGEVLVGPFVGQGEFLVITDYGTGNPYNSMTPLISGEIGEDLAFYLTESQQTPSAVGLNVLLDENDKVKVAGGFLVQVLPGAKEAEIARFEKRIQEMPAISRLLESDDHIEALLAAIYGNEPYKRLSEEEIRFQCDCNKERFMNALATLPKADLEEMRDQDQGAEIVCQFCQTAYHFDQNDLEELIRDKS
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDIA4_CAEEL
Sequence: MMFDRRFFALVVLLCVSAVRSTEDASDDELNYEMDEGVVVLTDKNFDAFLKKNPSVLVKFYAPWCGHCKHLAPEYEKASSKVSIPLAKVDATVETELGKRFEIQGYPTLKFWKDGKGPNDYDGGRDEAGIVEWVESRVDPNYKPPPEEVVTLTTENFDDFISNNELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTMKIIRNGRRFDYNGPREAAGIIKYMTDQSKPAAKKLPKLKDVERFMSKDDVTIIGFFATEDSTAFEAFSDSAEMLREEFKTMGHTSDPAAFKKWDAKPNDIIIFYPSLFHSKFEPKSRTYNKAAATSEDLLAFFREHSAPLVGKMTKKNAATRYTKKPLVVVYYNADFSVQYREGSEYWRSKVLNIAQKYQKDKYKFAVADEEEFAKELEELGLGDSGLEHNVVVFGYDGKKYPMNPDEFDGELDENLEAFMKQISSGKAKAHVKSAPAPKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDATINDAPSQFAVEGFPTIYFAPAGKKSEPIKYSGNRDLEDLKKFMTKHGVKSFQKKDEL
What are the official names of this protein?
Probable protein disulfide-isomerase A4, ERp-72 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein disulfide isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: TRMB_CYTH3
Sequence: MARKKLMRFKWNEEVHNLFQPEKENYKAYKGKWHEYFKNDNPVILEVGCGRAEYTTGLAALFPENNYIGLDIKGARLWKGSSLSIETGLTNTAFIRTKLQNLEEFFEPGEVKGIWITFPDPKPRESEAKLRLSGLRFMNIYRRLMPAGGKVFFKTDNRVLFDHTLEVLTDQTLKIKDLVFTHDLYQSPLLAEHYGIQTTYEKTYLNQGVQINYLKFEFLPL
What is the function of this protein?
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine(46)-N(7))-methyltransferase, tRNA(m7G46)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
Protein: HIS1_SALPA
Sequence: MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYLTLRRLDFGGCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQQLIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POL_VILV1
Sequence: MAKQGSKEKKGYPELKEVIKATCKIRVGPGKETLTEGNCLWALKTIDFIFEDLKTEPWTITKMYTVWDRLKGLTPEETSKREFASLQATLACIMCSQMGMKPETVQAAKGIISMKEGLQENKEAKGEKVEQLYPNLEKHREVYPIVNLQAGGRSWKAVESVVFQQLQTVAMQHGLVSEDFERQLAYYATTWTSKDILEVLAMMPGNRAQKELIQGKLNEEAERWVRQNPPGPNVLTVDQIMGVGQTNQQASQANMDQARQICRQWVITALRSVRHMSHRPGNPMLVKQKNTESYEDFIARLLEAIDAEPVTDPIKTYLKVTLSYTNASTDCQKQMDRTLGTRVQQATVEEKMQACRDVGSEGFKMQLLAQALRPQGKAGHKGVNQKCYNCGKPGHLARQCRQGIICHHCGKRGHMQKDCRQKKQQGKQQEGATCGAVRAPYVVTEAPPKIEIKVGTRWKKLLVDTGADKTIVTSHDMSGIPKGRIILQGIGGIIEGEKWEQVHLQYKDKIIRGTIVVLATSPVEVLGRDNMSELGIGLIMANLEEKKIPITEVRLKEGCKGPHIAQWPLTQEKLEGLKEIVDRLEKEGKVGRAPPHWTCNTPIFCIKKKSGKWRMLIDFRELNKQTEDLAEAQLGLPHPGGLQRKKHVTILDIGDAYFTIPLYEPYRQYTCFTMLSPNNLGPCVRYYWKVLPQGWKLSPSVYQFTMQKILRGWIEEHPMIQFGIYMDDIYIGSDLGLEEHRGIVNELASYIAQYGFMLPEDKRQEGYPAKWLGFELHPEKWKFQKHTLPEITEGPITLNKLQKLVGDLVWRQSLIGKSIPNILKLMEGDRALQSERYIESIHVREWEACRQKLKEMEGNYYDEEKDIYGQLDWGNKAIEYIVFQEKGKPLWVNVVHSIKNLSQAQQIIKAAQKLTQEVIIRTGKIPWILLPGREEDWILELQMGNINWMPSFWSCYKGSVRWKKRNVIAEVVSGPTYYTDGGKKNGRGSLGYIASTGEKFRIYEEGTNQQLELRAIEEACKQGPEKMNIVTDSRYAYEFMLRNWDEEVIRNPIQARIMELMHNKEKIGVHWVPGHKGIPQNEEIDRYISEIFLAKEGRGILQKRAEDAGYDLICPQEISIPAGQVKRIAIDLKINLKKDQWAMIGTKSSFANKGVFVQGGIIDSGYQGTIQVVIYNSNNKEVVIPQGRKFAQLILMPLIHEELEPWGETRKTERGEQGFGSTGMYWIENIPLAEEEHNKWHQDAVSLHLEFGIPRTAAEDIVQQCDVCQENKMPSTLRGSNKRGIDHWQVDYTHYEDKIILVWVETNSGLIYAERVKGETGQEFRVQTMKWYAMFAPKSLQSDNGPAFVAESTQLLMKYLGIEHTTGIPWNPQSQALVERTHQTLKNTLEKLIPMFNAFESALAGTLITLNIKRKGGLGTSPMDIFIFNKEQQRIQQQSKSKQEKIRFCYYRTRKRGHPGEWQGPTQVLWGGDGAIVVKDRGTDRYLVIANKDVKFIPPPKEIQKE
What is the function of this protein?
Catalyzes viral DNA integration into the host chromosome, by performing a series of DNA cutting and joining reactions.
What are the official names of this protein?
Gag-Pol polyprotein.
What is the protein family that this protein belongs to?
Belongs to the retroviral Pol polyprotein family.
What are the subcellular locations of this protein?
[Matrix protein p16]: Virion. SUBCELLULAR LOCATION: [Capsid protein p25]: Virion. SUBCELLULAR LOCATION: [Nucleocapsid protein p14]: Virion.
Protein: GBRB1_HUMAN
Sequence: MWTVQNRESLGLLSFPVMITMVCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH
What is the function of this protein?
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain.  Functions also as histamine receptor and mediates cellular responses to histamine.  Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site.  Functions as ligand-gated chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit beta-1, GABA(A) receptor subunit beta-1.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: FUCK_SALTI
Sequence: MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVTTFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFISSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAEHDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPETPWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGGGSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV
What is the function of this protein?
Catalyzes the phosphorylation of L-fuculose.
What are the official names of this protein?
L-fuculokinase, L-fuculose kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RL36_MYCMM
Sequence: MKVNPSVKPICDKCRVIRRHGRVMVICSDPRHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: PILG_PSEAE
Sequence: MEQQSDGLKVMVIDDSKTIRRTAETLLKKVGCDVITAIDGFDALAKIADTHPNIIFVDIMMPRLDGYQTCALIKNNSAFKSTPVIMLSSKDGLFDKAKGRIVGSDQYLTKPFSKEELLGAIKAHVPSFTPVDAVS
What is the function of this protein?
Plays an essential role in both cAMP-dependent and independent regulation of twitching motility (PubMed:28583947).  Regulates the cAMP-independent coordination of type IV pilus (T4P) biogenesis and retraction that plays a role in surface and host cell adhesion, colonization, biofilm maturation, virulence, and twitching (PubMed:20345659, PubMed:28583947).  In addition, phosphorylated PilG is necessary for cAMP production via regulation of the adenylate cyclase CyaB.  Acts therefore as a response regulator of the chemosensory system/Chp system (PubMed:20345659, PubMed:27354279).
What are the official names of this protein?
Protein PilG.
Protein: SURE_MOOTA
Sequence: MLILVTNDDGINAPGIKALSRSLARVGRVAVVAPEKERSAIGHGITMHKPLRATEVTWEGPVEMALAVNGTPADCVKLALDALLDEEPSLVVSGINMGANLGTDVLYSGTVSGALEGCINGRPSLAVSLAGEGGVDFSFAADFTSRLAGVIIKRGLPAGTLLNLNIPCLPPGEIKGLAITRLGRRRYCNTITRRLDPRGRAYYWLAGEVEDLDQEPDTDIGALGQGRISITPLHLDLTNYSYQQELAAYLSFLWPGQGNR
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KHDR2_HUMAN
Sequence: MEEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGKKEDEEKKYLDVISNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLVPDYNDEIRQEQLRELSYLNGSEDSGRGRGIRGRGIRIAPTAPSRGRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVPTPRARGAPTVPGYRAPPPPAHEAYEEYGYDDGYGGEYDDQTYETYDNSYATQTQSVPEYYDYGHGVSEDAYDSYAPEEWATTRSSLKAPPQRSARGGYREHPYGRY
What is the function of this protein?
RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion.  Binds both poly(A) and poly(U) homopolymers.  Phosphorylation by PTK6 inhibits its RNA-binding ability (By similarity).  Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer.  Can regulate alternative splicing of NRXN1 in the laminin G-like domain 6 containing the evolutionary conserved neurexin alternative spliced segment 4 (AS4) involved in neurexin selective targeting to postsynaptic partners.  Regulates cell-type specific alternative splicing of NRXN1 at AS4 and acts synergystically with SAM68 in exon skipping.  In contrast acts antagonistically with SAM68 in NRXN3 exon skipping at AS4.  Its phosphorylation by FYN inhibits its ability to regulate splice site selection.  May function as an adapter protein for Src kinases during mitosis.
What are the official names of this protein?
KH domain-containing, RNA-binding, signal transduction-associated protein 2, Sam68-like mammalian protein 1, SLM-1, hSLM-1.
What is the protein family that this protein belongs to?
Belongs to the KHDRBS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DTX1_XENLA
Sequence: MSRPGVLLPVNGHNFGSQGGPPRVVVWEWLNEHGRWRPYTATVCHHIENALREDGRGRVALGQVDAQLTPYVIDLQTMHQYRQDTGTIRPVRRNFFEPSSAPGKGIVWEWENDAGSWTPYDTEICIAIQNAYEKHHPYLDLTTLGFCYLVHFHSMCQVNRQTHRKRRLRRRMDLAYPLTMGSIPKSQSWPVGSGSGLPCSCPQCLLVNSTRAASNAILASQRIKVPSGPPPALPPPPPPPIHPSGLRQSNTYSGGAAGWGRTGEGMRSTGGIRNGSGFSRSQSVPGAAPYPGQNNLNRPGEQRTSGSSSRASIPPGVPALPVKNLNGSGPVHPALAGMTGILMCAAGLPVCLTRAPKPILHPPPVSKEDIKPVSGVSGICRKTKKKHLKKSKNPEEVVRRYIQKVKSPPDEDCTICMERLVTASGYDGVLSHRGIRAELVGKLGKCNHMYHVLCPVAMYNNGNKDGSLQCPTCKAIYGEKTGTQPPGKMEFHVIPHSLPGFSDCKTIRIVYDIPSGMQGPEHPNPGKKFTARGFPRHCYLPDNDKGRKVLRLLLAAWERRLIFAIGTSSTTGESNTVVWNEIHHKTEFGSNLTGHGYPDPNYLDNVLTELHRQGVMEERSLPY
What is the function of this protein?
Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations.  Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context.  Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
What are the official names of this protein?
E3 ubiquitin-protein ligase DTX1, Protein deltex-1, xDtx1, RING-type E3 ubiquitin transferase DTX1.
What is the protein family that this protein belongs to?
Belongs to the Deltex family.
Protein: SECY_MICLU
Sequence: MLKAIARIVRTPDLLRKIAFTLGLIAVYRMGDFVPATGVDYPAVQQCLAAGNAQGGLYSFVNMFSGGALLQVSVFALGIMPYITASIIVQLLRVVIPRFEQLHQERRRGQATLTQYTRYLTLALALLQATTMASLARTGALLGCSLPLLRDGSILTVLLVVIALTTGCLIVMWFGERITENGVGNGMSLLIFTSIAAGFPAGLGQVVQTQGWRVFAIVMGIGLLTMLAIVFVEESQRRIPVQYAKRQIGSRTVGGSSTYIPVKVNMANVIPVIFASSVLMLPGILIQFNTPQDGSAPAPWITWLSRYFGSGDHPVYMALYFLLIIGFTYFYVSITFNPVEISDNMKRYGGFIPASAPAGPTERYLQYVISRITFVVGALYLGIVAMIPLIAFAVIGTSQNFPLGGTSILIMVGVGLQTVKQVSAQMEQRHYEGLLR
What is the function of this protein?
The central subunit of the protein translocation channel SecYEG.  Consists of two halves formed by TMs 1-5 and 6-10.  These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back.  The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug.  The plug probably moves laterally to allow the channel to open.  The ring and the pore may move independently.
What are the official names of this protein?
Protein translocase subunit SecY.
What is the protein family that this protein belongs to?
Belongs to the SecY/SEC61-alpha family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LIPA_FRAAA
Sequence: MSAVAPEGRPLLRLEARNAQTPIERKPPWIRTRMRTGPEYSDVKGLVRAAGLHTVCEEAGCPNIYECWEDREATFLIGGDVCTRRCDFCQIDSGRPTPLDRDEPRRVAESVRTMGLRYATVTGVARDDLADGGSWLYGETVRQIHALSAGTGVEVLIPDFGGRADQLDEVFGAAPEVLAHNLETVPRIFKRIRPAFRYERSLDVLRQARAAGLVTKSNLILGLGETAEEIHAAMRDLHAAGCELLTVTQYLRPTPRHHPVERWVRPEEFLDWERVGAELGFSGVMSGPLVRSSYRAGRLYQQAITARGEGHTAASDLPKSVLETSHTQ
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA1_SYNAS
Sequence: MISVMAPGSEKTGKVETILKKRVLLAISGGVDSSVAALLLKEEGYEVAGVTMCLGVREEENKVRCCGREAIEDARGVCEILGIPHYVLDYAPLLETCVIDKFVREYRLGRTPNPCIDCNRYLKFGHLLDSARTMGFDYLATGHYAKIERKESRWILKKAKDLVKDQTYFLYPIPVAALEHILFPLADRTKDEVREIARQALLPIAEKPESQDLCFVTQDSYRDFLQEQGCPVHPGPIVDRSGRVLGEHSGTVFYTIGQRHGLGISSPFPLYVVAIDVAGNSVIVSGKEDVYAQGLVAGEMNWLTPERPQEAEARIRHRKRTCSCRIVPEGDRIRVYFAEDQDAVTPGQAVVLYQEDEVLGGGVIEEALHYAN
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA 1.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPX6_HUMAN
Sequence: MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFAGKHVLFVNVAAYUGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLKYVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIRWNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH
What are the official names of this protein?
Glutathione peroxidase 6, GPx-6, GSHPx-6.
What is the protein family that this protein belongs to?
Belongs to the glutathione peroxidase family.
What are the subcellular locations of this protein?
Secreted.
Protein: ARAD_GEOSE
Sequence: MLEELKQAVLEANLQLPQYRLVTFTWGNVSGIDRERGLVVIKPSGVAYDKLTIDDMVVVDLTGNVVEGDLKPSSDTPTHLWLYKQFPGIGGIVHTHSTWATVWAQAGKGIPALGTTHADYFYGEIPCTRPMTNEEIQGAYELETGKVITETFRFLDPLQMPGVLVHGHGPFAWGKDPANAVHNAVVLEEVAKMAARTYMLNPNAKPISQTLLDRHYLRKHGANAYYGQ
What is the function of this protein?
Involved in the degradation of L-arabinose.  Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5-phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: MNMA_MYCLB
Sequence: MKVLAAMSGGVDSSVAAARMVDAGHDVVGVHLALSTVSGTLRTGSRGCCSKEDVSDARRVADVLGIPFYVWDFAEKFQEDVIDNFVSAYARGETPNPCVQCNQRIKFSALSVRALMLGFDTVATGHYARLSGGRLRRAVDRGKDQSYVLAVLTAQQLRHAAFPIGDTLKRQVRAEAARRGLLVADKPDSHGICFIPSGNTRAFLSECIGIRRGSVVDADGTVLAEHDGVHGFTVGQRKGLGIVGPGPNGRPRYVTAIDADTATVYVGDAADLGVHTLIGRAPVFTAGAAPLGPVQCVVQIRAHGETAVAVVELIGDELFVRLCEPLRGVARGQTLVLYRLDPDGDEVLGSATIASMSA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_SHEB9
Sequence: MAKVPSRSPRKRVRKQVADGMAHIHASFNNTIVTITDRQGNALSWATSGGSGFRGSRKSTPFAAQVAAERAGAAAQDYGLKNLEVFVKGPGPGRESAIRALNAVGYKITNITDVTPIPHNGCRPPKKRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: FOXN5_XENLA
Sequence: MYLRFANRKPYEKLHLSTALEDWDMSEELKLSITADQYFAGADDKVERYTLRRQHSTELSPTRSEEGDFQECKFRPSLWLVVDPNLVIPCPEWINRIPPAPELTSPPLQLQRQLSVEYSTVEDSEDEAPTSCSDLMTDDDNDDSYNPCQPKNKHKRAKCLGKKMRVQKGLTELESWARPPLNYCNLISLALRNSEDGCLNVQQIYSFVRDHFPFFRIAPDGWKNTVRHNLCFSSSFEKSSGWVCADGHRRSCLWKLTRQGRRKFRNEMHALSDDLLHVLRRSMKKPALMELMFGM
What are the official names of this protein?
Forkhead box protein N5.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZN593_DICDI
Sequence: MGRYSGHGGTHTKKKQYKRARSTKNRAKDIDQIFDEIQPETIDKFSKFEVDPDLPGMGQNYCIHCSKHFVTNEDLQSHIKGKPHKIRVKELKTKPYSLAESQIPVDNGVKLNRDANGVPTTTDVTGTIKKSTTTTTTTTTV
What is the function of this protein?
Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome.
What are the official names of this protein?
Zinc finger protein 593 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZNF593/BUD20 C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: PER41_ARATH
Sequence: MSSVINVLFVVLVFVPSIYSAPPPNLTKDYYQKTCPDFNKIVRETVTPKQGQQPTTAAGTLRLFFHDCFMEGCDASVLIATNSFNKAERDDDLNESLPGDAFDIVTRIKTALELSCPGVVSCADILAQATRDLVTMVGGPFYEVKLGRKDGFESKAHKVKGNLPLANQSVPDMLSIFKKNGFTLKELVALSGGHTIGFSHCKEFSNRIFPKVDPELNAKFAGVLKDLCKNFETNKTMAAFLDPVTPGKFDNMYFKNLKRGLGLLASDHILFKDPSTRPFVELYANNQTAFFEDFARAMEKLGRVGVKGEKDGEVRRRCDHFNKLNV
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 41, Atperox P41.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.