PharMolix/UniProtQA huggingface dataset:
Protein: TIP39_MOUSE
Sequence: METCQMSRSPRERLLLLLLLLLLVPWGTGPASGVALPLAGVFSLRAPGRAWAGLGSPLSRRSLALADDAAFRERARLLAALERRRWLDSYMQKLLLLDAP
What is the function of this protein?
Plays a role as a potent and selective agonist of PTH2R resulting in adenyl cyclase activation and intracellular calcium levels elevation.  Induces protein kinase C beta activation, recruitment of beta-arrestin and PTH2R internalization.  May inhibit cell proliferation via its action of PTH2R activation.  Neuropeptide which may also have a role in spermatogenesis.  May activate nociceptors and nociceptive circuits.
What are the official names of this protein?
Tuberoinfundibular peptide of 39 residues, TIP39, Parathyroid hormone 2.
What is the protein family that this protein belongs to?
Belongs to the parathyroid hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNC1_PSE14
Sequence: MTLRLSGIELRHSDGTLALRGLDLNIAGGERVAIIGPSGAGKTTLLNLLASALPPSAGQLEVLGADPWQLSSKRRQRLRSRIALVHQAPPLPARQRVITAVSAGKLGQWGLGKSLLNLLHPLDVSGTREVLARLDLADKLFERCQQLSGGQLQRVGIARALYQAPELLLADEPVSAMDPRLADHTLALLCQHAIEHHVTLVASLHAVELALAHFPRIIGVRDGQIHFDLAANEVDRQHLDTLYANEQLSPQPAPDVSETPWTPRC
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: BC11B_MOUSE
Sequence: MSRRKQGNPQHLSQRELITPEADHVEATILEEDEGLEIEEPSSLGLMVGGPDPDLLTCGQCQMNFPLGDILVFIEHKKKQCGGLGPCYDKVLDKSSPPPSSRSELRRVSEPVEIGIQVTPDEDDHLLSPTKGICPKQENIAGPCRPAQLPSMAPIAASSSHPPTSVITSPLRALGVLPPCFPLPCCGARPISGDGTQGEGQMEAPFGCQCELSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEPGPASTSLTPRLTIPPPLGPETVAQSPLMNFLGDSNPFNLLRMTGPILRDHPGFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMRLNPMAIDSPAMDFSRRLRELAGNSSTPPPVSPGRGNPMHRLLNPFQPSPKSPFLSTPPLPPMPAGTPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELPGDLKAADGDFRHHESDPSLGPEPEDDEDEEEEEEELLLENESRPESSFSMDSELGRGRENGGGVPPGVAGAGAAAAALADEKALALGKVMEDAGLGALPQYGEKRGAFLKRAGDTGDAGAVGCGDAGAPGAVNGRGGAFAPGAEPFPALFPRKPAPLPSPGLGGPALHAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSSENGSLRFSTPPGDLLDGGLSGRSGTASGGSTPHLGGPGPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS
What is the function of this protein?
Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals (PubMed:12717433).  Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (By similarity).  Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes (PubMed:16809611).  Tumor-suppressor protein involved in T-cell lymphomas.  May function on the P53-signaling pathway.  Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.
What are the official names of this protein?
B-cell lymphoma/leukemia 11B, BCL-11B, B-cell CLL/lymphoma 11B, COUP-TF-interacting protein 2, Radiation-induced tumor suppressor gene 1 protein, mRit1.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_BACMK
Sequence: MTKGILGRKIGMTQVFAENGELIPVTVIAANPNVVLQKKTTETDGYNAIQLGFEDKREKLTNKPEQGHTAKASTTPKRFIREIRDADVDGLEVGQEVKVEVFAAGEIVDVTGISKGKGFQGVIKRHGQSRGPMSHGSRYHRRPGSMGPVAPNRVFKGKKLAGRMGGDQVTIQNLEIVQVDTERNLLLVKGNVPGAKKSLVVVQGAVKVSK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CCA_BURM9
Sequence: MKIYAVGGAIRDALLGLPVRDRDYVVVGATPEQMAAQRFRPVGKDFPVFLHPDTHEEYALARTERKTAAGYHGFQFYYAPDVTLEQDLVRRDLTINAMAREVSPDGALVGPVVDPFGGQADLRAKLFRHVGDAFVEDPVRILRVARFAARFAEFAVAPDTAALMRAMVDAGEVDALVPERVWQELARGLMEAKPSRMFAVLRECGALARILPEIDALFGVPQRADYHPEVDTGVHVMMVIDHAAKQGYSLPVRFAALTHDLGKATTPADVLPRHIGHEGRSVDLLKPLCERLRVPNECRDLALVVAREHGNLHRVMEMGAAALVRLLERADALRKPARFAEALQASEADARGRLGLETKPYPQAERLRQALVAARAVDAGAIAQGLAGEPAKIKDAVHRARVRAVAQAVGVAD
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: RRAA_ECO57
Sequence: MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE
What is the function of this protein?
Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity.  Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.  Modulates RNA-binding and helicase activities of the degradosome.
What are the official names of this protein?
Regulator of ribonuclease activity A.
What is the protein family that this protein belongs to?
Belongs to the RraA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_ECOLI
Sequence: MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNMIGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.  Contacts the A site tRNA.
What are the official names of this protein?
30S ribosomal protein S19, Small ribosomal subunit protein uS19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RSSA_PICST
Sequence: MSLPASFDLTPEDAKLLLAANVHLGSKNVQVHNKPYVYKTRPDGVNVINIGKTWEKIVLAARIIAAVPNPSDVAVCSSRTFGQRAVLKFAAHTGATPIAGRFTPGNFTNYITRSFKEPRLVVVTDPRTDAQAIKESSYVNIPVIALTDMDSPSEYVDVAIPCNNKGKHSIGLIWWLIAREVLRLRGIIPDRTTEWSVMPDLYFYRDPEEIEQNAAEEAKTTEDVEEAAPVDADEWTGETEEVDWAESGATPAVEDAAASNW
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
What are the official names of this protein?
40S ribosomal protein S0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METN1_SALTY
Sequence: MIKLSNITKVFQQGTRTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTEGSVQVGGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPKEEIKRRVTELLDLVGLGDKHDSYPANLSGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQARLKASPETDSVPMLRMEFTGQSVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQEETQAAIAWLQDHHVKVEVLGYV
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: LST4_CANGA
Sequence: MGERFEGLENLNDECKVKLFGCRMRAPGSGTGGHESIEYRLLILEENAEMVCRQRYRTILDYSSRGHGSMGLKHDEMTNGNVSAPFITASELRQYIYGSPIRSKTRVTEDKFRIIPNSRQLLITRVFYPRRTSMNLHGTFPKNYQSSDRRVSITMCLPSYLLADISDSWADIDGWLTQTERHLMATSFHVVETQDNFVTLVNKLLIPALRSCHEIPRLFLYPQDNIDFIHTWFKDVFNWIELKEGTKLSFLPFLIAKTLIEYRDDPQESECHRIVITSGNLVIANKLVFILGGLLKPRYDGEMKIMITPVSTPTPSNHLMPPSMNGSNESSYHSSSNSHTPSKLKIPATINEHRPSRPRYSSTENIHVQSRTMDIPIVKSDQSPFSTSRGWKIPSSYRSATSSVSISSDESLAEVIQPSSLKSTTSIPFQNFSSSLSNQLYSSSYGSWFNGSITGSFTNSNPLSNGTSNMATFSSSFKKNNISSIFQSNSPTAGTDSWERPENNTGLNPNITLQRTASNSSLRHMLTPYQQQLISPSTNSEYDEYPWFGATNNAGGATVGTSSETVGSQQPVLLQGAHMDTTTLLDSIRTSNNNGAYTFPLKNVGFDRDCSSLDHHKLLTSCFEEIFEGDIDANKVTTMVPCSDIAVHIHSKQEDSEGVTSHPRVVIDVDIPGTTISKYPEELLPRYTMYLSHFNPFFKLQAIPATNEIENKIVHGLKRDFISEKCDVSKTLFISMRSRSIKEIVVRKTTSINTPSNSSNQDPRNKSKGSMLKQKIKKVFSNGTCTGRVTPVLNNCVAFVEAALMSAMSLYSDPTIDKKYRDERILKIFLAVAHYNVDEV
What is the function of this protein?
Involved in extracellular amino acid uptake.  Required for the protein trafficking from the Golgi to the plasma membrane (By similarity).
What are the official names of this protein?
Protein LST4.
What is the protein family that this protein belongs to?
Belongs to the LST4 family.
Protein: FLIE_BRUA4
Sequence: MYDSIMSISARNALSRLSETVAEKGVGSTSAPQAVPAAPGASFGEVLSQMTDSVGQKLQTAEATSIQGIKGDAPVRDVVSSVMEAEQSLQTAIAIRDKIVQAYLEISRMPI
What are the official names of this protein?
Flagellar hook-basal body complex protein FliE.
What is the protein family that this protein belongs to?
Belongs to the FliE family.
What are the subcellular locations of this protein?
Bacterial flagellum basal body.
Protein: PAND_PROMH
Sequence: MLRTMLQGKLHRVKVTQADLHYEGSCAIDQDFMDAAGILENEAIDIYNVDNGERFSTYAICAERGSGIISVNGAAARRAAVGDRLIICSYVQIPDSDARSHKPNIAYFEGDNEMKRIAKAVPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CNGA1_MOUSE
Sequence: MKTNIINTWHSFVNIPNVIVPAIEKEIRRMENGACSSFSDDDNGSLSEESENEDSFFRSNSYKRRGPSQREQHLPGTMALFNVNNSSNKDQEPKEKKKKKKEKKSKADDKNENKKDPEKKKKKEKEKEKKKKEEKTKEKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMIIARACFDELQSDYLEYWLIFDYVSDVVYLADMFVRTRTGYLEQGLLVKDRMKLIEKYKANLQFKLDVLSVIPTDLLYIKFGWNYPEIRLNRLLRISRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVYYSISKAIGFGNDTWVYPDVNDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVLDSEYIFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQSRVDAIKQYMNFRNVSKDMEKRVIKWFDYLWTNKKTVDEREVLRYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGRQILMKDGLLDINIANMGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIETEFSALEEPGGESELTESLQD
What is the function of this protein?
Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway.  When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.
What are the official names of this protein?
cGMP-gated cation channel alpha-1, Cyclic nucleotide-gated cation channel 1, Cyclic nucleotide-gated channel alpha-1, CNG channel alpha-1, CNG-1, CNG1, Cyclic nucleotide-gated channel, photoreceptor, Rod photoreceptor cGMP-gated channel subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA1 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CH10_RHOE4
Sequence: MASVNIKPLEDKILVQANEAETTTASGLVIPDTAKEKPQEGTVVAVGEGRVNEQGNRIPVDVKEGDTVIYSKYGGTEIKYAGQEYLILSARDVLAVVSK
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SCO21_RICCN
Sequence: MRNNKNQMYIIKIFIALAMITGIIFLCLLYSSLTPSKLKIGVKTSNMDDSPKIKFTLIDQEGKKFDSTHLQGHLSLIYFGTTYSLYDNQTLKRVEDIIKILKKENILVQVVFITLDSEHDTSEVLKKYLEKIDDNFIGLTGRVEDIEQLADQFKVFFYTSKIFDVKTNKYELQHSNFVYLISSQGKFLKHYYLGLPKNG
What are the official names of this protein?
SCO2-like protein RC0042.
What is the protein family that this protein belongs to?
Belongs to the SCO1/2 family.
Protein: PRIB_SHEPC
Sequence: MTTNSLVLSGTITRSRRFKSPAGIAHSVIMLEHKSQRYEADMLRNVYVQIQVILSGPRFESVADNLKAGVEVQVQGFMTLQQGRNGQNRLVIHAENVELKT
What is the function of this protein?
Binds single-stranded DNA at the primosome assembly site (PAS).
What are the official names of this protein?
Primosomal replication protein N.
What is the protein family that this protein belongs to?
Belongs to the PriB family.
Protein: SLX4_ASHGO
Sequence: MDLRRAERNLKILGDANSDEDMPVAHSVEETQGQALFSESDEADAEEDAAESPQSGVGGRTTTAESGGEEHREQVFLSTQVQGRIDEFEATEGARRQFRQLVTGFTYAQEDGEANAGGRTAKRVPKVRRTRRNNTKVRSLTEFNTENFERLRKEDRARSLLTMLSGKTQKVNNLLRGLQQERSRERAFHGCSVYNEGEWREIVRLLHERLPKATRSDVACIKSYVYGDGLDETPWCASHARPPDCPAQSQERQGTCGPGDDELRIFTLSQLLEDQSASEDVIPDSMDAGDAVSLGSPQPQAGLSQHSFCPDSTATSPLRPPATPLTRAPASPLPVRVYTAPASPLDYIPDSEDDPYVLQGPSQARSPPSLLEVRRTLKNIGVRPGRSAAAVRKAAAAVARIEAASDAASLGTASDADRRSALFLRMTALVRRSPRLLAHIYCLRPVALDDLRAVLEADDDFIALLDDSLIRQWADFTGICVKNDTSDSQRPPQPLESQ
What is the function of this protein?
Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA (By similarity).
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PLSX_RUBXD
Sequence: MRIAVDALGGDNAPQEIVAGALAAARRLPGVEILLVGEPGAVEPLLERAPGNVSLRPSGGAVRMDEEPAAALRSRPDASVAVAARLVRSGEADALFSAGNTGAAVAASLLYIGRIGGCRRPAIATVLPFSHPTLLLDVGATVSCRAQDLLNFAILGSVFARRYLETEGAPRVGLLNVGEEPGKGHDLAREAHRLLAASPQVEFAGNVEGRDLGSGRADVVVTDGFTGNAVLKTAEGVARECLRLVREALLGSLAGRVAALAARPRLLAVRDRVDPENYGGSFLLGVRGAVVIGHGNSTARGVENALAGIARAGGGLVAELEATLARQRAASGREGA
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: LIPA_CUPPJ
Sequence: MSDALIASSSEAPQSPAEQYDPTRKQKSADKTARIPIKIVPAEKLKKPDWIRVKAATGNSRFYEIKDILRANNLVTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDVNEPGNLARTIAQLKLNYVVITSVDRDDLRDGGAQHYVDCISQTRELSPATRIEVLVPDFRGRLDKALDILQACPPDVMNHNMETVPRLYKQARPGADYAHSLKLLQEFKRRNPNVPTKSGLMVGLGETDEEILEVMRDMRAHDIDMLTIGQYLAPSNHHLPVLRYVHPDTFKMFEEEAYKMGFTHAAVGAMVRSSYHADQQAHQAGFA
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CFA45_CHLRE
Sequence: MPQTPPRSGGYRSGKQSYVDESLFGGSKRTGAAQVETLDSLKLTAPTRTISPKDRDVVTLTKGDLTRMLKASPIMTAEDVAAAKREAEAKREQLQAVSKARKEKMLKLEEEAKKQAPPTETEILQRQLNDATRSRATHMMLEQKDPVKHMNQMMLYSKCVTIRDAQIEEKKQMLAEEEEEQRRLDLMMEIERVKALEQYEARERQRVEERRKGAAVLSEQIKERERERIRQEELRDQERLQMLREIERLKEEEMQAQIEKKIQAKQLMEEVAAANSEQIKRKEGMKVREKEEDLRIADYILQKEMREQSLAAEKERIAKEKEMETARLRAMQERAADKQSELDELRARRYQEAKEREWRQKERAYAERQASMQQELANARTAQQASKLKQKAEMARLEHDEFMRVLDVNRAKEYDELQQTVNAMTLNSKYKEELLAQIQANEERRKRERSHYLEEGARLREAAEKERQLLLQIKDRKLGELESAGVPGKYRAELEKMKIRS
What are the official names of this protein?
Cilia- and flagella-associated protein 45, Flagellum-associated protein 45.
What is the protein family that this protein belongs to?
Belongs to the CFAP45 family.
What are the subcellular locations of this protein?
Cell projection, cilium, flagellum.
Protein: RM17_DICDI
Sequence: MYHGQKLAKLGRESHHRMLMLRTMVTQLIRHERIKTTLAKAKALRKEADRIITIAKRNTRLSHSLVYSYVTDKQVIPKLFKELRLRFGDRPGGYTRVLKAGSRLSDRSKMAYIEYVENDLVPLRDYKANNSKFAVIRKPTPQGTVFNFEEKETGKIYSSAISLNNRFKRLEQLKKQSTSSSN
What are the official names of this protein?
Probable 39S ribosomal protein L17, mitochondrial, L17mt, MRP-L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL2_TROWT
Sequence: MAVRKSNPLTPARRGMSFSDFAEITRATPHKSLLSKLSKTGGRNNHGRITARHIGGGHKRRYRLVDFRRSDKDGVKAKVAHIEYDPNRTARIALLHFLDGAKRYILAPSGLKQGDVVESGSSADIRPGNSLCIRDIPVGTILHAVELRPGQGAKLARSAGSSVRLSAKDGDFAILKLPSGEIRMVSLSCRATIGEVGNGQRLNVSLGKAGRSRWCGVRPSVRGVAMNPVDHPHGGGEGKTSGGRHPVSPWGRPEGKTRRANKPSDRFIIRRKSRKRR
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: CNPD3_COLP3
Sequence: MTITEPYSPNNQPITFAQITDSHLFSSVDGLHHGHNVLANLKKVLLSICDNPSIKYIIFTGDLTQDHTEQSYQNFVDCVLECHITVPIYYLAGNHDEPKLLDKYFSASPFQADKEINLSHWQVQLVDSKSATPAGYVGEQALVKLKDAIQKNKNQLLMMHHHPIDVGYFIDKHGLQNKDAFWQVINSYDNIKAIACGHVHGDMTLTNAITSPINEPVVLYTCPATSIQFDPTVDGVAALSKGPGYRLFSLYADGQLNTEVVML
What are the official names of this protein?
Probable cyclic nucleotide phosphodiesterase CPS_4178.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase class-III family.
Protein: DBP5_COCIM
Sequence: MASENTTETPSVPAGGPLAARISRPEGDANPPSTEAEKPAAEDDSGKGPSIPQVDGASEDQRGSELQDSEFDVNVKLSDLQADPNNPLYSIKSFEELGLAEPIQMGLSKMNFRRPSKIQERALPLLMANPPTNMIAQSQSGTGKTAAFVLNILSRLELTPEKQKSPQALVLAPSRELARQIVGVIQAMGTFVEGLFVATAVPMEMNRNQRVEASIVVGTPGTVQDLIKKRLFNTQHLRVLVLDEADNMLDQQGLGDQCIRVKSLLPRTIQVVLFSATFPDFVVRYAHKFAPNSNQLTLKHEELTVEGIKQLYLDCESDEHKYEILVKFYGLLTIGSSIIFVKTRASAAEIERRMVAEGHTVVSLTGGIEGQKRDEIIDRFRNGTAKVLITTNVLARGIDVSTVSMVINYDIPELHLPGAARRMADAQTYLHRIGRTGRFGRVGVAVSFVSNQEEWQMLQDIQKYFSTNIERVDTRDWDDVEKKVKKIIKPSAVAR
What is the function of this protein?
ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus.  May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex.  May also be involved in early transcription (By similarity).
What are the official names of this protein?
ATP-dependent RNA helicase DBP5.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX19/DBP5 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils.
Protein: BETA_PARP8
Sequence: MAAKEYDYIIIGAGSAGNVLATRLTEDRDVTVLLLEAGGPDYRFDFRTQMPAALAYPLQGRRYNWAYETDPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNALDYDGWAERKGLENWTYLDCLPYFRKAETRDAGANDYHGGDGPVHVTTSKRGVNPLFEAMVEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTANGRRASTARGYLDQARPRPNLTIVTYATTDRILFSGKRAQGVVYLDGQAQITAHARREVLLCSGAIASPQILQRSGVGPGGWLRDLDIPVVLDLPGVGQNLQDHLEMYMQYECKEPVSLYPALLLRNQPAIGIEWMLKGTGIGASNHFEAGGFIRTRDDDPWPNIQYHFLPVAINYNGTNAIKMHGFQAHVGSMRSPSRGRVKLRSRDPREHPSILFNYMAEALDWREFRDAIRITREIIAQPALDRFRGRELSPGAELQSDAQIDAFVRARAETAYHPSCSCAMGYDDMAVVDGEGRVHGLEGLRVVDASIMPRITTGNLNAPTIMLAEKIADRIRGRAPLARSTAPYYVANGAPARGAKHVEHAPAPSVAAHTH
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: SKOR2_MOUSE
Sequence: MASSPLPGPNDILLASPSSAFQPDALSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPSAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAATGGAGPGAGGPGGGCVAGVGVGASAGAGAAAGTKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFGLCHKKEDAGTAAEALGGAGAGSAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGDSPALLRQAFLDLAEPGGAGGSAEAAPPPGQPPPVVANGPGSGPPATGGTGARDTLFESPPGGSGGDCSAGSTPPAEQGVTSGTGSASSGAGSVGTRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGTPHSAPAHHHHHHHHPHHHHHHPPQPPSPLLLLQPQPDEPGSERHHPAPPPPPPPPPLAPQPHHRGLLSPEGTSCSYPSEDSSEDEEDEEEEQEVDVEGHKPLEGEEEEDGRDPEDEEEEDEETRVLLGDSLVGGGRFLQGRGLSEKGSGRDRTTPAVGAFPLALNSSRLLQEDGKLGDSGGSDLPAPPPPPLAPQKASSSGGSRPGSPVHHPSLEEEPSYKDNQKPKENNQVIISTKDDNFSDKNKGHGFFITDSDSSGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEFQVLKGNTSFPVFNNFQDQMKRELAYREEMVQQLQIIPYAASLIRKEKLGAHLSKS
What is the function of this protein?
Acts as a TGF-beta antagonist in the nervous system (By similarity).  Exhibits transcriptional repressor activity.
What are the official names of this protein?
SKI family transcriptional corepressor 2, Fussel-18 homolog, LBX1 corepressor 1-like protein, Ladybird homeobox corepressor 1-like protein, Transcriptional corepressor Corl2.
What is the protein family that this protein belongs to?
Belongs to the SKI family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: LIPM_BACSU
Sequence: MQKETWRFIDSGNASPAFNMALDEALLYWHSEKKIPPVIRFYGWNPATLSVGYFQNIKKEINFEAVHKYNLGFVRRPTGGRGVLHDQELTYSVIVSEEHPEMPATVTEAYRVISEGILQGFRNLGLDAYFAIPRTEKEKESLKNPRSSVCFDAPSWYELVVEGRKVAGSAQTRQKGVILQHGSILLDLDEDKLFDLFLYPSERVRERMQRNFKNKAVAINELIEKRVTMDEARKAFKEGFETGLNIHLEPYELSQEELDFVHHLAETKYASDEWNYKR
What is the function of this protein?
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation.  Is also able to catalyze the reverse reaction.  Octanoyl-CoA can also act as a substrate although very poorly.  Does not display lipoate protein ligase activity, despite its sequence similarity to LplA.
What are the official names of this protein?
Octanoyltransferase LipM, Octanoyl-[acyl-carrier-protein]:[GcvH] N-octanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the octanoyltransferase LipM family.