PharMolix/UniProtQA huggingface dataset:
Protein: PRGR_MACSY
Sequence: MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFQGSQTSDTLPEVSATPISLDGLLFPRPCQGQDPLDEKTQDQQSLSDVEGAYSRAEATRGTGGSSSRPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGGKAGDSSGTAAAHKVLPRGLSPSRQLLLPASGSPHWSGAPVKPSPQPAAVEVEEEDGSESEDSAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTTMDFTHVPILPLNHALLAARTRQLLEEESYDGGAGAASAFAPPRSSPSASSTPVAVGDFPDCAYPPDAHPKDDAYPLYGDFQPPALKIKEEEEGAEVSARSPRSYLVAGANPAAFPDFPLGPPPPLPPRAPPSRPGEAAVTAAPAGASVSSASSSGSTLECILYKAEGAPPQQGPFAPPPCKAQGAGGCLLPRDGLPSTSTSASAAAAGAAPALYPALGLNGLPQLGYQAAVLKEGLQQVYPPYLNYLRPDSEASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRALDAVALPQPVGIPNESQALSQRFTFSPGQDIQLIPPLINLLVSIEPDVIYAGHDNSKPDTSSSLLTSLNQLGERQLLSVVKWSKLLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK
What is the function of this protein?
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcriptional activator of several progesteron-dependent promoters in a variety of cell types.  Involved in activation of SRC-dependent MAPK signaling on hormone stimulation.
What are the official names of this protein?
Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases (By similarity).
Protein: INSI2_PAPAN
Sequence: MAEGETESPGPKKCGPYISSVTSQSVNLMIRGVVLFFIGVFLALVLNLLQIQRNVTLFPPDVIASIFSSAWWVPPCCGTASAVIGLLYPCIDRHLGEPHKFKREWSSVMRCVAVFVGINHASAKVDFDNNIQLSLTLAALSIGLWWTFDRSRSGFGLGVGIAFLATLVTQLLVYNGVYQYTSPDFLYVRSWLPCIFFAGGITMGNIGRQLAMYECKVIAEKSHQE
What is the function of this protein?
Oxysterol-binding protein that mediates feedback control of cholesterol synthesis by controlling both endoplasmic reticulum to Golgi transport of SCAP and degradation of HMGCR.  Acts as a negative regulator of cholesterol biosynthesis by mediating the retention of the SCAP-SREBP complex in the endoplasmic reticulum, thereby blocking the processing of sterol regulatory element-binding proteins (SREBPs) SREBF1/SREBP1 and SREBF2/SREBP2.  Binds oxysterol, including 22-hydroxycholesterol, 24-hydroxycholesterol, 25-hydroxycholesterol and 27-hydroxycholesterol, regulating interaction with SCAP and retention of the SCAP-SREBP complex in the endoplasmic reticulum.  In presence of oxysterol, interacts with SCAP, retaining the SCAP-SREBP complex in the endoplasmic reticulum, thereby preventing SCAP from escorting SREBF1/SREBP1 and SREBF2/SREBP2 to the Golgi.  Sterol deprivation or phosphorylation by PCK1 reduce oxysterol-binding, disrupting the interaction between INSIG2 and SCAP, thereby promoting Golgi transport of the SCAP-SREBP complex, followed by processing and nuclear translocation of SREBF1/SREBP1 and SREBF2/SREBP2.  Also regulates cholesterol synthesis by regulating degradation of HMGCR: initiates the sterol-mediated ubiquitin-mediated endoplasmic reticulum-associated degradation (ERAD) of HMGCR via recruitment of the reductase to the ubiquitin ligase RNF139.
What are the official names of this protein?
Insulin-induced gene 2 protein, INSIG-2.
What is the protein family that this protein belongs to?
Belongs to the INSIG family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: NCAP_VSIVG
Sequence: MSVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKGLDGVLPDGVSDASRTRADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDSKYTPDDSTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK
What is the function of this protein?
Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases.  The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication.  Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA.  In contrast, when associated with RNA, it is termed N.  During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity).
What are the official names of this protein?
Nucleoprotein, NP, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the vesiculovirus nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm. Note=The nucleocapsid is synthesized in the cytoplasm, and is subsequently transported via microtubules to the cell periphery.
Protein: NTPPA_OLEA2
Sequence: MNVDGPFTASCPVVLASGSPRRQEFLRAMGVPFSVDTAGASEPEPVEGEAAVAYARRAACAKTLPVARRHAAACVIGADTVVALDGVIMGKPAGHAHALSMLRALAGARHEVVSACCICLPGNAQEPVVLHAVTSVWMHRWDDAALKAYIATGEPADKAGAYGIQGIGAFLVSRIDGSWSNVVGLPLTELLTELQRRGVVVPSGAQTAEQDGHAPDVRD
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
dTTP/UTP pyrophosphatase, dTTPase/UTPase, Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YhdE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASNA_SALNS
Sequence: MKTAYIAKQRQISFVKLHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAEVHKQFGLAPFLPEQIQFVHSQELLSRYPDLDAKGRERAIAKELGAVFLVGIGGKLSDGHRHDVRAPDYDDWSSASELGYAGLNGDILVWNPVLEDAFELSSMGIRVDADTLMRQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAQVRESIPAIL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_PARD8
Sequence: MADLKAFAEQLVNLTVKEVSELATILKEEYGIEPAAAAVAVAGPAAGGAAAAAEEKTSFDVVLKAAGANKLAIVKLVKELTGLGLKEAKDMVDSAPSAIKEGIAKADAEAMKKQLEEAGAEVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: ACEK_SHIBS
Sequence: MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQLAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRYGEMLF
What is the function of this protein?
Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue.  This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon.  When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
What are the official names of this protein?
Isocitrate dehydrogenase kinase/phosphatase, IDH kinase/phosphatase, IDHK/P.
What is the protein family that this protein belongs to?
Belongs to the AceK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y8558_DICDI
Sequence: MTIIKSISIIADKSISKTNFIKINNENDSIVIMYTNNQKISKSRGQILDSHIVVNPLIDFNLIF
What are the official names of this protein?
Putative uncharacterized protein DDB_G0271918.
Protein: CAF17_USTMA
Sequence: MITRRALVDPLARQPLKTSTNILRAASIIPRCTFGSTASSAAADKTSSTWKLAKVPHRGVVQVSGRDTVKLLQGLVSNDVKALDSTTLTHQPPNMVYAGFMNPQGRMLADVFIHRQPANQDGSPRWLLDIDSRTLPSLVAFIKKFKLRSKVKLTDLSTDYHVVQAWDSNSQAPPTIAEKLSIDPRSPSIGYRGVLSAAEILDVAAAASTVDGLEYTLHRITNGVAEGALDFPQASSLPLENNLDYMHGVDFRKGCYVGQELTARTHHTGVVRKRIVPLSFYLAGTPPPASIHDVDPAFPHQLPTHLAEIRSKPISTASEAATKPARGKAAGKFTSGVYNVGLACLRLEQVRRWADSSSADPNSKHDALEFSVLSADGETTLLARPWIPSWWPHDQPVPSDQDT
What are the official names of this protein?
Putative transferase CAF17, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the GcvT family. CAF17 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: ODO1_RICCN
Sequence: MGEDFKKTGYLFGGNAVFVEELYKQYLANPASVDQTWQEFFAGIKDNNTLLNKSTAKIIIPDEIKKESLNNNLSSEDLNSLKAKEMINAYRKHAHYLANLDPLGLELRKTKNDLKLNIETFGLDSGQLEENINITDEFVGTWNCKLSELVTKFDKVYTGSIGVEFEQIENVAGKNWLYNKLESEVTFSSEDKKTILNDLVEVEGFEQYLHTKFPGAKRFSIEGGDASIVAMSKAIDLSMHQGVSEIVIGMAHRGRLNTLTKVVGKPYKAVIADFISGSVFPDELNVSGDVKYHLGYSSDRTLEDKKIHLSLADNPSHLEAVNPIVAGKVRAKQDILGDTKRSKVKAILVHGDAAFCGQGVVAESLSMSPLAAYDIGGILHFVINNQLGFTANAADTRASRYSTEFAKIIAAPILHVNGDDIEAVLKATNIAVEYRQKFGKDVVVEIICYRKYGHNEGDEPMYTQGKMYNIIKNKLTPGNIYANELVKSGVIDNNYFAKLKEEFKAKLDKEYEQAKSYKQEAHFLGGLWQGISRTRTQATITGISKKTLHDLGTKLCEIPKDFAVNPKLVKLFEARKATLTADQPIDWATAEQLAFASLLASGTNIRLTGQDSGRGTFSHRHSVLHNQIDGTTYIPLNNLSKEQAKYEVADSNLSEYAVLGFEYGYSLANPKNLVLWEAQFGDFANGAQIIFDQFISSSETKWLRMSGLVVLLPHAFEGQGPEHSSARLERFLQLAAENNMYVTYPTTPASIFHLLRRQILDDTRKPLIVMSPKSLLRHKYAVSKLDELGENTTFLPVLDEVTKVDTNNITKVILCSGKVYYDLFEMRGNNSNIAIIRLEQLYPFEKKLVASLLKKYNRTQEFIWCQEEPKNMGTWCYIVSHLNDALKEAGIKNEFKYVGREESASPAVGSLQVHNKQQEKLLRTALGI
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: RS9_CALS4
Sequence: MATIQYYGTGRRKEAVARVRLMPGKGNIIINNKSLEEYFPLETLRYTVKQPLILTETIDKFDVYVKVSGGGLSGQAGAIRHGIARALVKADAELRPILKKAGFLTRDPRMKERRKYGLKKARKAPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: COAX_MYCBT
Sequence: MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTGTAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAYDRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHTVDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FH21A_ARATH
Sequence: MSPVEISGADAVVSPPMRGRVPLPPPPPPPPPPMRRRAPLPPPPPPPMRRRAPLPPPPPPAMRRRVLPRPPPPPPPLPMFDAEVLCCCYPPTRVRREAPLPPPPLIFVGAPPPTCALKGIVCCFPCPSKKKSSLKRFNWVKITRALPGSLWDELQIQQVCHGDIEDEQILCAIELDVSEIETFFSLGAAKPEKDPLIDLRRATDTELTLMLLNIRLPADMMAAIMAMDESVLDDDEIRGLINLFPTKENMELLMSYTGGKWTLEKWEQYFQELRKVLRVESKLRVFYFKIQFSTKITQFKKRLNVVNSACEEVCSSQKLKEIMKKITCLGNTSNQGTGRGVTVGFNLDSLCVKSMHNFCKVLASEASDLLDVHKDLQSLESASKKQLKSLAEEMQDIIRDLEKLNQELTAAETDGPDSQVFRNVCWFCSYGYFDQPWI
What are the official names of this protein?
Putative formin-like protein 21a, AtFH21a.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-II subfamily.
Protein: EFG_STAA2
Sequence: MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETHEGASQMDWMEQEQDRGITITSAATTAAWEGHRVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAAPIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAVAETSDELMEKYLGDEEISVSELKEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVIDYLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDPYVGKLTFFRVYSGTMTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGEKNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVIIGGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKSSAQVQGKFSRQSGGRGQYGDVHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLIDVKAKLYDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVTSRRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSIAEDIIKKNKGE
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ROK_BACSU
Sequence: MFNEREALRLRLEQLNEAEVKVIREYQIERDKIYAKLRELDRNGSPSEIKKDFRSEKKPDSLPVLAELAAQEIRSYQPQSQQQSVQPQLQSISSLPAGIPDGTTRRRRGTARPGSKAAKLREAAIKTLKRHNAAIKSSELQKEIEKESGLEIPNMTTFMQSLIKMYPEVKKPYRGQYILEGEIESAESANE
What is the function of this protein?
Repressor of comK, the master regulator of competence development (PubMed:11849533).  Overexpression seems to be lethal (PubMed:11849533).  Represses at least 20 genes that specify membrane-localized and secreted proteins, including some that encode products with antibiotic activity (PubMed:15743949).  Binds to many AT-rich sites in the chromosome, many of which are known or thought to derive from horizontal gene transfer; helps keep mobile element ICEBs1 quiescent in the genome (PubMed:21085634).  Binds to its own promoter and is thus probably autoregulatory (PubMed:21085634).
What are the official names of this protein?
Repressor Rok.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Not uniformly distributed in the nucleoid, it forms several clusters (PubMed:21085634).
Protein: NUOD_RICTY
Sequence: MTNKTITLNLGPQHPATHGVLRLILEMDGEVVNNADPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEHAFALAVESLLECSVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYERVSGSRMHANYFRPGGVAEDLPEKLLEDINKFIEQFPSKLNDIENLLNENRLWKQRLVDIGVVSQKDAMDWGFSGPMLRGSGIAWDLRKSNPYDVYDEMDFEVPVGKNGDCYDRYLVRILEMYESIKIIKQCIAKMPKGQVKTDNPKLTPPTREKMKESMEAMIHHFKLYTEGYDVPIGETYKAVEAPKGEFGVYLYSQGGNKPYRCRIKAPGFAHLQGLNFMSKGHLISDVITIIATLDIVFGEIDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MURA_HALOH
Sequence: MGKFLIKGGNPLKGKIKVSGAKNAALPIITAALLADTPSKLIDIPHLRDVTNLCNILEKMGAGVEFENNIVSIDPTTLTEAEADPELARKLRASYYILGVLLAKEGWARTSLPGGCNIGNRPIDLHLKGFKALGADVKLDHGIVEVKANKLKGARIYLDYPSVGATINIMLAATRAEGKTVIENAAREPEIVDLANYLTVMGAKIKGVGTDIIKIEGVDSLKGAEHRIIPDRIEAGTYMIAAALNKGDVFVDNVLAEHLKSLIAKLKEMGIQIKEEISGIKVVSNDKLKAVDVKTLPYPGFPTDLQSQIMVLLTQAEGTSLVIETVWENRFMHVDELKRMGADIKIDGHSALIKPSQLTGAEVTATDLRAGAALILAGLVAEGETEVRNINHVERGYEDIEEKLSGIGADIRKVK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSD_PINMS
Sequence: MDVMNFLLNLVVPPAGLLMLAFAWPSLAFFRACEWALRIIYGEDMEGKVVIITGASSGIGEQIAYQYAKRRANLVLVARREHRLRSIREKARTLGAKNVLVIAADVVKEEDCKRFIDETINQYGHLDHLVNNAGLGHSFLFEEASDTSGFAHMMDINFWGSVYPTFFALPHLRRRNGRIIVNASVEGWLPMPRMSLYNAAKAAVVSFYETLRIEIGGAIDITIATPGWIESDMTRGRFMTEEGEVLFKEEPREMYVGPYPVAYTEECARTIVSGACKGQRYVRFPMWYNVFFLYRVFVPDLLDWTYRLLFLNHFITTASKDHTLHDFKGARKKLLITPTSLQLLHHQQHQSPKSSE
What is the function of this protein?
Has dehydrogenase activity against corticosterone (11 beta-hydroxysteroid) and estradiol (17 beta-hydroxysteroid) in the presence of NADP(+).  May be involved in signal transduction regulated by various sterols.
What are the official names of this protein?
11-beta-hydroxysteroid dehydrogenase, 17-beta-hydroxysteroid dehydrogenase, Steroleosin.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Lipid droplet. Membrane; Single-pass type II membrane protein. Note=Surface of oil bodies. Exists at a monolayer lipid/water interface.
Protein: SECA_AGRVS
Sequence: MVSLGGIARKIFGSSNERRIRGNKPRVAAINALEDSIKALSDAELAAKTEEFKGELAKGKTLDDILIPAFAVAREASRRALGMRPFDVQLIGGMILHENAIAEMKTGEGKTLVATLAVYLNALSGKGVHVVTVNDYLASRDAAIMAKLYSFLGLTTGVIVHGMNDDERREAYACDITYATNNELGFDYLRDNMKYERGQMVQRGHNYAIVDEVDSILVDEARTPLIISGPLDDRSDLYTTIDAFIPMLSAEDYEIDEKQKSANFSEVGTEKLENLLKDAGLLKGVSLYDVENVAIVHHINNALKAHKLFQRDKDYIVRNDEIVIIDEFTGRMMPGRRYSEGQHQALEAKEKVTIQPENQTLASITFQNYFRMYSKLAGMTGTANTEAEEFQDIYGLSVIEVPTNLPILRIDEDDEVYRTFEEKFKAIIEEIKASASRNQPVLVGTTSIEKSELLATMLRQSGFTDFSVLNARYHEQEAYIVSQAGVPGAVTIATNMAGRGTDIQLGGNIDMRLERDLEGMEPGPERDAKEQAIREEVKALKEKALAAGGLYVIATERHESRRIDNQLRGRSGRQGDPGRSKFYLSLQDDLMRIFGSDRMDSMLQKLGLKEGEAIVHPWINKALERAQKKVEARNFDIRKNLLKYDDVLNDQRKVIFEQRVELMDAEDLTETIDDMRHELIDTIVRTHIPEKAYAEQWDVAGLKTAMTGILNLDLPIEDWAQEEGIAEDDIVERVKKAADEVMAEKTERFGPEIMAYIERSVLLQTIDNLWREHIVNLDHLRSVVGFRGYAQRDPLQEYKAEAFELFQALLANMREGVTAQMMRVEIVREAPPEPTLPIMHGHHEDPQTGQDEFAAADGIVAPENRNPADPSTWGKVGRNEMCPCGSGKRFKHCHGALLA
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: FIXI_RHILV
Sequence: MSCCTMDAESVLALSTTSFSAEEVRLASQPLGEGLRQLDLSVSDVHCGGCISTIERALLTLPFVKTARVNLTARRVTCVYQEEIEARATDPSKILGEINSAGYRAHLFTPSAPESDKTRNQLLLAIGVSGFAAPNIMLLSVSVWSGADAATRDMFHWISAMIAAPALVYAGRFFFKSAWNALRHGRTNMDVPISVTVSLSYAVSLWETVHHGEHAWFDASVSLLFFLLIGRTLDHIMREKARAAINGLARLAPRGALLINPDGSRRYIAVEEIAAGDEISIAAGERVPVDGIVVSGESDLDLSIVTGESSPVTVASDSEVSSGAMNLTGSLVLRATRIAKNSLLSEIIGLMEAAEGGRARYRRIADRAATLYSPVVHLLALVSFLAWGFLGGDWKQAMLVAVAVLIITCPCALGLAVPVVQVVAAGELFRKGIMVKDGSALERLAETDTVAFDKTGTLTMGSSRLVRVDAMDESAAAIARGLAAHSRHPLSRALVRDTETAPISFDRVTEIPGGGLEARNGADIYRLGNAAFACGTSFVPRTADSPFSEVVLSKNGVDLARFFFDDTLRPGACEAIDRLDAAGLETLIVSGDRQTVVDNTAHALGIDRALGSLTPKQKVEECQRLNGEGRRVLMVGDGINDAPALAAAHVSMAPATASDIGRQAADLVFFIDRLDAVPEAIAVARRSASLIRQNFALAIGYNVLAVPIAIAGLATPLIAAVAMSTSSIIVVTNALRLNGFGKRPDMHIRRGIGRSAEVKAA
What is the function of this protein?
FixI is a pump of a specific cation involved in symbiotic nitrogen fixation.  The four proteins FixG, FixH, FixI, and FixS may participate in a membrane-bound complex coupling the FixI cation pump with a redox process catalyzed by FixG.
What are the official names of this protein?
Nitrogen fixation protein FixI, E1-E2 type cation ATPase FixI.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYS_BACCQ
Sequence: MLDIKFLRTNFEEVKAKLQHRGEDLTDFGRFEELDTRRRELLVQTEELKSKRNEVSQQISVLKREKKDAEALILEMREVGEKVKDLDNELRTVEEDLERLMLSIPNIPHESAPVGETEDDNVVARTWGEVKEFAFEPKPHWDLATDLGILDFERAGKVTGSRFVFYKGAGARLERALISFMLDLHTDEHGYEEVLPPYMVNRASMTGTGQLPKFEEDAFRIESEDYFLIPTAEVPVTNMHRDEILNKDQLPIRYAAFSSCFRSEAGSAGRDTRGLIRQHQFNKVELVKFVKPEDSYEELEKLTNDAERVLQLLELPYRVMSMCTGDLGFTAAKKYDIEVWIPSYGTYREISSCSNFEAFQARRANIRFRREPNGKPEHVHTLNGSGLAIGRTVAAILENYQQEDGTIIIPEVLRPYMGGKTVIK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPCS_ORYSJ
Sequence: MAVYIAREATKLWRKVCAEIAVELQLLFEKWRLLLAGLVFQYIHGLAARGVHYLHRPGPLLQDLGFMALPELGQDKGYVSESVFTFIFISFLLWSFHPFIYHSKRFYTVLLWRRVLAFLVASQFLRIITFYSTQLPGPNYHCREGSKMATLPPPHNVLEVLLINFPRGVLFGCGDLIFSSHMIFTLVFVRTYHKYGSKRLIKILAWLMAIIQSLLIIASRKHYSVDVVVAWYTVNLVVFFIDNKLPEMPDRTNGSSLLPVTAKDKDGRTKEELHKLEKDCKMKEEFHKLLNGNTVDSTDRRQRVQMNGKHGEDINHTLSDATPNGT
What is the function of this protein?
Catalyzes the transfer of the phosphorylinositol group from phosphatidylinositol (PI) to phytoceramide, an essential step in sphingolipid biosynthesis.  May play an important role in modulating plant programmed cell death (PCD) associated with defense by promoting sphingolipid metabolism and regulating ceramide accumulation.
What are the official names of this protein?
Phosphatidylinositol:ceramide inositolphosphotransferase, Inositol-phosphorylceramide synthase, IPC synthase, Protein ENHANCING RPW8-MEDIATED HR-LIKE CELL DEATH 1, Sphingolipid synthase.
What is the protein family that this protein belongs to?
Belongs to the sphingomyelin synthase family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein.