PharMolix/UniProtQA huggingface dataset:
Protein: Y973_HAEIN
Sequence: MTINLTKFSLTILVALTLTACGSSGGSGDSQSAHTPSTSIHTQNNSTPNKNTSTPPVNVSNANNLEIKNNDKTGGAFIISGEDGHVTLKKVDITTNSDLNVLYIDGTKIPLSSPSIKSNGWLNIRSGTGKVSIDGIETSRDLKVCCGKYTDTRIGKVLSKNKNEDTYFFYNGNLTRNMPVGGTVNYNTGDSILSSYHDELGDTDEAVGTSQFSADFVNKKLTGSLSVNEKKLNINADISGNTFSGTTQSDAFKSQGIAEGKFYGENAKELGGLVKANDNSWSGAFAAKK
What are the official names of this protein?
Uncharacterized protein HI_0973.
Protein: PORIM_RAT
Sequence: MALCARAALLLGALQVLALPGAVAQETYAQGSPSGNHSVPLLTANVNVTENTTMQVVSNQTSQISTVKPSSVLPKNVTAATVRPATIKVSTPGVSPHVTPSASKSTPKTSASPNSTQTSASMTTTAHSSLLTSVTVSATTHPTKGKGSKFDAGSFVGGIVLTLGVLSILYIGCKMYYSRRGIRYRSIDEHDAII
What is the function of this protein?
Implicated in oncotic cell death, characterized by cell swelling, organelle swelling, vacuolization and increased membrane permeability.
What are the official names of this protein?
Porimin, Transmembrane protein 123.
What is the protein family that this protein belongs to?
Belongs to the CD164 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RL7_MICLU
Sequence: MNKEQILEAIKAMTVLELNDLVKAIEEEFGVTAAAPVVAGGAAAAAEEKTEFDVVLASAGAEKIKVIKVVREITGLGLKEAKEVVDNAPKALKEGVSKDEAEEIKAKLEEVGASVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12, MA1/MA2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PRP2_SOYBN
Sequence: MASLSSLVLLLAALILSPQVLANYENPPVYKPPTEKPPVYKPPVEKPPVYKPPVENPPIYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPVYKPPVEKPPIYKPPVEKPPVYKPPYGKPPYPKYPPTDDTHF
What is the function of this protein?
This is a developmentally regulated putative cell wall protein.
What are the official names of this protein?
Repetitive proline-rich cell wall protein 2.
What is the protein family that this protein belongs to?
Belongs to the plant proline-rich protein superfamily. ENOD12 family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ATG15_NEUCR
Sequence: MLPSGKRKADAFSCTSAARVTAKLALSFLALSTTPLVNAFSYEEPNAQIVLPIDASPIKPLLPEPPAPAEHKFTLRHIYHHGTYEHPTLHRKKDVPAQNADVWLAADDEYGQERIGTLKARSSPVRIQRLADRRPSVVDPMVAYARQQGYASVLSPEAWTMDEVAGPDITDKDTIISLALMAADAYVQTPDGADWEDVGAPFNRSLDFGWEGDGLRGHVFADETNSTIVIGLKGTSVAVFDGDGTTTNDKVNDNLFFSCCCAQQGPWTWHQVCDCATGTYSCNNTCVVQALRQENRYYQAGRELYANVTELYPDANVWIVGHSLGGAMSSLLGLTYGDPVVTFEAVPEALPAKRLGLPIPPGSDPDAPQTREYTGAFHIGHTADPVYVGTCNGATATCAIGGYAMESACHTGRECVYDTVGDLGWRVGIGTHKIRVVISDVLRKYEKVPECKFTPECRDCGNWKMYESNGTETTTTSSTPTSTSMTRTRTETCKTPGWWGCLDETTTTTGMATTTTSEMPTTSTTTCHTPGWFGCKDKTTTSTASTTTTPIATTATTTTTSSTTCLTPGKFWGCYDKTATTDIGSPSTSTELTITSAPALPSSVLTPSATATPPEGQPDDSGKRCRGRTWYGVCKDYEGGEGPVNDL
What is the function of this protein?
Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies.  Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles.  The intravacuolar membrane disintegration by atg15 is critical to life span extension (By similarity).
What are the official names of this protein?
Putative lipase atg15, Autophagy-related protein 15.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. Lipase family.
What are the subcellular locations of this protein?
Endosome, multivesicular body membrane; Single-pass type II membrane protein. Prevacuolar compartment membrane; Single-pass type II membrane protein. Note=From ER, targeted to vacuolar lumen at the MVB vesicles via the Golgi and the prevacuolar compartment (PVC).
Protein: WECF_SALPC
Sequence: MTVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLHFYGSKKVLAQAVIAKAKANRRQRFFFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGELLYFPTRMDPSLNAMAKERQRAGKLTILVGNSGDRSNQHIAALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQAGLALFSAENLQILSEKMEFDAYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SPC29_YEAS8
Sequence: MDYSNFGNSASKKFQDDTLNRVRKEHEEALKKLREENFSSNTSELGNKKHYRAQERMSSPLHRLSPTGKSDDRKVKSPLDDKLRRQLREGNTRLPPPPFSSYGMPPTNRSNLDRIRRRTSSPVRTDKFASQNVIDDQRLEIKYLERIVYDQGTVIDNLTSRITRLESFILNSISDRGDKNFASLEHSRSFSGFPTNKTYGLQMGGLYENDMPYRRSSDNINKEGAREDRSSQIHIENESTEDILKILSSSFHN
What is the function of this protein?
Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication.  Links the central plaque component SPC42 to the inner plaque component SPC110 (By similarity).
What are the official names of this protein?
Spindle pole component 29.
What is the protein family that this protein belongs to?
Belongs to the SPC29 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: PP2B_ASPFU
Sequence: MEDGTQVSTLERVIKEVQAPALSTPTDEMFWSPEDPSKPNLQFLKQHFYREGRLTEEQALWIIHAGTQILRSEPNLLEMDAPITVCGDVHGQYYDLMKLFEVGGDPSETRYLFLGDYVDRGYFSIECVLYLWALKIWYPNSLWLLRGNHECRHLTDYFTFKLECKHKYSERIYEACIESFCALPLAAVMNKQFLCIHGGLSPELHTLEDIKSIDRFREPPTHGLMCDILWADPLEEFGQEKTGDYFVHNSVRGCSYFFSYPAACAFLEKNNLLSIIRAHEAQDAGYRMYRKTRTTGFPSVMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCTPHPYWLPNFMDVFTWSLPFVGEKITDMLIAILNTCSKEELEDETPTSVSPSAPSPPLPMDVESSEFKRRAIKNKILAIGRLSRVFQVLREESERVTELKTAAGGRLPAGTLMLGAEGIKQAITNFEDARKVDLQNERLPPSHEEVIKRSEEERRAALERAQQEADNDTGLATVARRISMSAGSGRSRRQRDAARETREA
What is the function of this protein?
Calcium-dependent, calmodulin-stimulated protein phosphatase.  This subunit may have a role in the calmodulin activation of calcineurin.
What are the official names of this protein?
Serine/threonine-protein phosphatase 2B catalytic subunit, Calmodulin-dependent calcineurin A subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2B subfamily.
Protein: RRF_JANMA
Sequence: MTVADAKKTADQKMQKSIETLKADLAKVRTGRAHTGILDHVMVEYYGNPTNLSQVANVTLIDARTIGVQPFEKKMVAVVEKAIREADLGLNPATQGELIRVPTPPLTEERRKEMVKLVKSEAEDAKIAVRNIRRDANESLKKLVKEKACSEDEERRAQDEIQKLTDKFVIEIDKLVVEKEKEVLTV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_DICTD
Sequence: MANTKSAIKRIKISERNRIRNRVRLGKIKFYTKQFLKFLNENNIEEAKKILPEVISAIDKAAQKGTLHKNTAARKKSKLMKLLNQKLSANLSS
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: AROB_KLEP7
Sequence: MERLTVTLGERSYPITIAAGLFNDPASFLPLKSGDQAMLVTNETLAPLYLDTVRSVLEQSGVNVDSVILPDGEQYKSLAVMDTVFTALLQKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFWQPVSVVVDLNCLKTLPKRELASGLAEVIKYGVILDGEFFSWLENNIDALLALDDTAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFRAQDTQRIIDLLKRAGLPVRGPQEMSAQAYLPHMMRDKKVLAGEMRLVLPLAIGSSELRGGVPHDVVLGAIADTQQAQQ
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNLJ_MYCGE
Sequence: MMDVKLKIQQLVNLIKNYDYHYYVLSEPLIDDFEYDMLYKSLQQLEKDHPDLIQIDSPTQRVGGEAVKGFKKLNHNSPMLSLENAFSTKEIANFIDNINFQTNSKNEFVVEPKIDGVSISLTYKNGVLVHALTRGDGSVGEDVLNNVKTIKSIPLTIPFTKTIEIRGEIFVDKKTFLAINNQLEKPFANARNLAAGTIRNLNSEITAQRKLRALFYYIPNGLEESITTQTMVLEQLKQWKFPVSDTIRVFQNKFQLINYLEAFDKKREQLTFNLDGLVIKLNSLLFYQQLGATSKSPRWAIAFKFSPKFVQTKLTAVLITIGRTGRVNYTAKLESVNLDGTKVTAATLHNFDYIKTKDIRINDTVVIYKAGEIIPKVLKVNLEKRKNDTIIIQEQKYCPSCNSKLVKIVDEVDQYCTNETCKERNIQLINYFVSKTAMDINGLNINTITKLYEHNLVRSIVDLYDLKDKKNQVLKLDLKIGDKLFNKLVDNIENSKQKGMARLLTGLGIKHVGNVLAKNLANHFKNIKALQHASLENLISLNDVGITVAESLYNWFHDPNHLQLIEQLELRQVKTDQLPLKINFETNSIYFQKRFLITGSFNISRDQIKDLLSAKFDCQFASEVKPTVDFVIAGNKPTLRKINHAKELNIPIINEAIWT
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: CYC3A_DESAF
Sequence: MFKHTLIALTLLAAATLFSLPAFSQEDMTHVPTDAFGKLERPAAVFNHDEHNEKAGIESCNACHHVWVNGVLAEDEDSVGTPCSDCHALEQDGDTPGLQDAYHQQCWGCHEKQAKGPVMCGECHVKN
What is the function of this protein?
Exchanges electrons specifically with the basic cytochrome c3.
What are the official names of this protein?
Acidic cytochrome c3.
What are the subcellular locations of this protein?
Periplasm.
Protein: MED1_PONAB
Sequence: MKAQGETEESEKLSKMSSLLERLHAKFNQNRPWSETIKLVRQVMEKRVVMSSGGHQHLVSCLETLQKALKVTSLPAMTDRLESIARQNGLGSHLSASGTECYITSDMFYVEVQLDPAGQLCDVKVAHHGENPVSCLELVQQLREKNFDEFSKHLKGLVNLYNLPGDNKLKTKMYLALQSLEQDLSKMAIMYWKATNAGPLDKILHGSVGYLTPRSGGHLMNLKYYVSPSDLLDDKTASPIILHENNVSRSLGMNASVTIEGTSAMYKLPIAPLIMGSHPVDNKWTPSFSSITSANSVDLPACFFLKFPQPIPVSRAFVQKLQNCTGIPLFETQPTYAPLYELITQFELSKDPDPIPLNHNMRFYAALPGQQHCYFLNKDAPLPDGRSLQGTLISKITFQHPGRVPLILNLIRHQVAYNTLIGSCVKRTILKEDSPGLLQFEVCPLSESRFSVSFQHPVNDSLVCVVMDVQDSTHVSCKLYKGLSDALICTDDFIAKVVQRCMSIPVTMRAIRRKAETIQADTPALSLIAETVEDMVKKNLPPASSPGYGMTTGSNPMSGTTTPTNTFPGGPITTLFNMSMSIKDRHESVGHGEDFSKVSQNPILTSLLQITGNGGSTIGSSPTPPHHTPPPVSSMAGNTKNHPMLMNLLKDNPAQDFSTLYGSSPLERQNSSSGSPRMEICSGSNKTKKKESSRLPPEKPKHQTEDDFQRELFSMDVDSQNPIFDVNMTADTLDTPHITPAPSQCSTPTTYPQPVPHPQPSIQRMVRLSSSDSIGPDVTDILSDIAEEASKLPSTSDDCPAIGTPLRDSSSSGHSQSTLFDSDVFQTNNNENPYTDPADLIADAAGSPSSDSPTNHFFHDGVDFNPDLSNSQSQSGFGEEYFDESSQSGDNDDFKGFASQALNTLGVPMLGGDNGETKFKGNNQADTVDFSIISVAGKALAPADLMEHHSGSQGSLLTTGDLGKEKTQKRVKEGNGTSNSTLSGPGLDSKPGKRSRTPSNDGKSKDKPPKRKKADTEGKSPSHSSSNRPFTPPTSTGGSKSPGSSGRSQTPPGVATPPIPKITIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSSASTSRKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSHSRPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLKHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIRPLPEYSTEKHKKHKKEKKKVKDKDRDRDRDKDRDKKKSHSIKPESWSKSPISSDQSLSMTSNTILSADRPSRLSPDFMIGEEDDDLMDVALIGN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  Acts as a coactivator for GATA1-mediated transcriptional activation during erythroid differentiation of K562 erythroleukemia cells (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 1, Mediator complex subunit 1, Peroxisome proliferator-activated receptor-binding protein, PBP, PPAR-binding protein.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 1 family.
What are the subcellular locations of this protein?
Nucleus. Note=A subset of the protein may enter the nucleolus subsequent to phosphorylation by MAPK1 or MAPK3.
Protein: ARGP_SALPB
Sequence: MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD
What is the function of this protein?
Controls the transcription of genes involved in arginine and lysine metabolism.
What are the official names of this protein?
HTH-type transcriptional regulator ArgP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: BKRB1_MOUSE
Sequence: MASQASLKLQPSNQSQQAPPNITSCEGAPEAWDLLCRVLPGFVITVCFFGLLGNLLVLSFFLLPWRRWWQQRRQRLTIAEIYLANLAASDLVFVLGLPFWAENVGNRFNWPFGSDLCRVVSGVIKANLFISIFLVVAISQDRYRLLVYPMTSWGNRRRRQAQVTCLLIWVAGGLLSTPTFLLRSVKVVPDLNISACILLFPHEAWHFVRMVELNVLGFLLPLAAILYFNFHILASLRGQKEASRTRCGGPKDSKTMGLILTLVASFLVCWAPYHFFAFLDFLVQVRVIQDCFWKELTDLGLQLANFFAFVNSCLNPLIYVFAGRLFKTRVLGTL
What is the function of this protein?
This is a receptor for bradykinin.  Could be a factor in chronic pain and inflammation.
What are the official names of this protein?
B1 bradykinin receptor, B1R, BK-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y014_SYNY3
Sequence: MEWNESLLRLTVAFVLGSTLGIERQWRQRMAGLRTNTLVAIGAALFVIVSVLTNHDSSPTRIPAQIVSGIGFLAGGVILKEGLTVKGLNTAATLWCSAAVGTLCGQGLFSEAVLGSMMVLVANIALRPLSTFINHQPMHSTELECHYLCHLVCRGDEEANVRRILLDSLAEIKNIKLRSLRSHDLDEFNHFVEVEAAIICTARKDKFLEAVISKLSLNPSVKSVSWQALEQESG
What are the official names of this protein?
Uncharacterized protein slr0014.
What is the protein family that this protein belongs to?
Belongs to the MgtC/SapB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOB_LACH4
Sequence: MLNGHVVNYGKHRTRRSFSRIKEVLKLPNLTDVQTESYKWFLDKGIKEVFDDIMPISDFSGKLSLEYEGYKLQKPKYTVDEARDHDATYAAPMRVTLKLTNQETGEIKTQDVFFGDLPLMTESGSFIVNGAERVIVSQLVRSPGVYYTGDYDKNGRQIFGTTVIPNRGAWLEYETDAKNVSFVRVDRTRKLPLTVLIRAMGIGSDSDIIDMFGQSDTLQFTLDKDVHKNPADSRVAEAIKDIYERLRPGEPKTTDSSRSLLYARFFDPRRYDLAPVGRYKINKKLSLKNRLYGQTLAETLADPDTGEIIAKKDTVVTHEVMDKLAPYLDRDDFKMVTYQPSKEGVLPDPITVQEIKVYSKVDPEREVKLMSNGHIAEDVKHLTPADVLASINYFFALQDKIGTTDDIDHLGNRRIRRVGELLQNQFRIGLARMERVVRERMSIQDPLTVTPQQLINIRPIVASIKEFFGSSQLSQFMDQHNPLGELTHKRRMSALGPGGLTRDRAGYEVRDVHYTHYGRLCPIETPEGPNIGLINSLASYAIINKYGFIETPYRRVSWKTHKVTDKIDYLTADEEDNYIIAGANTPLNDDGSFKSDVILARQKEDNVEVTPDKIDYMDVIPKQVVSVASACIPFLENDDSNRALMGANQQRQAEPLINPHGSLVGTGMEYRAAHDSGAALIAKAAGTVEYVDANEIRIRREDGTLDKYTLEKYRRSNNSKSYNQTPNVKLGDHVDVSDVIANGPTMDHGELALGQNPLIAFMTWNMYNYEDAIMLSERLVKDDVYTSISIEDYESEARDTKLGPEEITRELPNIGEDALKDLDADGIVRVGAEVHDGDILVGKVTPKGVTELSAEERLLHAIFGEKAHEVRDTSLRVPHGGGGIVQDVKVYTREAGDELSPGVNTMVRVYIAQKRKIQVGDKMSGRHGNKGTVAAVVPEEDMPYLPDGTPVDICLNPMGVPSRMNIGQLLELHLGAAARQLGIHVATPVFAGANENDVWDTVRQAGIDKDGKTVIYDGRTGEPFHNRVSVGVMHYLKLTHMVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDVVGRVKAYEAIVKGERIPKPGVPESFRVLVKELQSLGLDIRVLDMNHNEIELRDMDEDSSEHLNIDSLSRMAEEQEKKKLAEETGKSGDKKENKKDADKPVAPADESDDKVSK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DXR_SERP5
Sequence: MKQLTILGSTGSVGTSTLAVVRENPDRFAIKALVAGRNVAVMAQQCIEFRPAYAAMADEGAARELRILLAENGIATEVMAGEQAACELAALDDVDQVTAAIVGAAGLLPTLAAIRAGKQVLLANKESLVTCGRLFMDAVQQSKTQLLPLDSEHNAIFQSLPESIQRQLGYSSLESHGVSRIVLTGSGGPFRTTPLEQFTAMTPDQACAHPNWSMGRKISVDSATMMNKGLEYIEARWLFNASAEQMEVILHPQSVIHSMVRYTDGSVLAQLGTPDMRTPIAHAMAYPQRVNSGVEALDFCRIGSLTFAEPERERYPCLYLAIEAFDAGQAATTALNAANEVAVAAFLQEQIRFTDIAAVNQKVVERLSLQEPSCIDAVLEIDRQAREVAVGLVKSLHN
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: CATK_MOUSE
Sequence: MWVFKFLLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDASLASFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGESWGNKGYALLARNKNNACGITNMASFPKM
What is the function of this protein?
Thiol protease involved in osteoclastic bone resorption.  Displays potent endoprotease activity against fibrinogen at acid pH.  May play an important role in extracellular matrix degradation (By similarity).  Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed:12782676).
What are the official names of this protein?
Cathepsin K.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
What are the subcellular locations of this protein?
Lysosome. Secreted. Apical cell membrane; Peripheral membrane protein; Extracellular side. Note=Localizes to the lumen of thyroid follicles and to the apical membrane of thyroid epithelial cells.
Protein: H18G1_CYRHA
Sequence: MKLSIIIIATSLVIAVVAFPSKDSKAIENDKTEQRMEIVVQETARACSKQIGDKCKRNCECCGKTVVCGTIYVGGKEVNQCMDKTSDNAILNGLGKGMNFMENTFSFCV
What is the function of this protein?
Putative ion channel inhibitor.
What are the official names of this protein?
Hainantoxin-XVIII-7, HNTX-XVIII-7.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 25 family. F7 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPB11_SCHPO
Sequence: MNQPERYELIELMGLPKVTYELDSKSPNAAVVTLEKEDHTLANMLANQLLSDERVLFAGYKVPHPLNHNFILRVQTVEDCSPKQVIVDAAKSLITHLEEIKVNFMREWELKMISVEGVEMEFS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.  Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs.  Pol II is the central component of the basal RNA polymerase II transcription machinery.  It is composed of mobile elements that move relative to each other.  RPB11 is part of the core element with the central large cleft (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase II subunit RPB11, RNA polymerase II subunit B11, DNA-directed RNA polymerase II 14.1 kDa polypeptide.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MDTG_ECOSM
Sequence: MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQLGVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMGLAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPMAGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNPKLILSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAPRLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQTLLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAVYSWNSLRRRRIPQVSN
What is the function of this protein?
Confers resistance to fosfomycin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtG.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UBIE_RICM5
Sequence: MNQTNFGLKKVDYTKKQGLVNNVFSNVADKYDLMNDLMSLGLHRLWKDEFIRQIPNLNSHILDVASGSGDIALKLAKKARDRVNNISLTLSDINEEMLKQAKKKAIDLNLFQNLKFTVASAEELPFPDDSFDYYTIAFGIRNVPDINKALKEACRVLKPMGKFICLEFSKVKEGYIKDFYKFYSFNIIPSIGQMIVGNKEAYEYLVESIELFPSQDEFRIMIKDAGFEEVGYKNLSGGIVAIHSAYTR
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: SYT_PROM3
Sequence: MPIITLPDGNKKKFDQPVTIMEVAESLGPGLAKAAIAGRVNGVLLDTCIPIEKDSEVNIITAKDQDGIETIRHSFAHLIGHAVKQLYPEAKMAIGPVIEDGFYYDIAYDQPFTPKDLEAIEARMKELVKLDYDVNVEIVSREEAHKEFEKRCEPYKIEIVDEIPENEIIKLYRHQEYTDMCRGPHVPNTRHLRTFKLMKVSGAYWRGDSNKTMLQRIYGTAWGSSKELKAYLKRLEEAEKRDHRRIAKQMSLFHTQEEAPGMIFWHAKGWAIYQVLEQYIRETLSLHAYQEIRTPQVVDRSLWEKSGHWEKFKDDMFTTTSENREYAIKPMNCPCHVQIFNQGLKSYRDLPIRLAEFGSCLRNEPSGSLHGLMRVRNFVQDDAHIFCTELQVQEEVSKFIDLVFEIYRSFGFDSVLIKLSTRPEKRVGSDEIWDKSEKALSDALDAKGLAWDLLPGEGAFYGPKIEFSLKDCLGRVWQCGTIQVDFSMPERLGASYVAEDSQRRTPVMLHRAILGSFERFIGILIEHYAGRMPVWLAPVQVAVMGITDRNAQTCQDVCKKLSALEYRTEVDLRNEKIGFKVREHTLQRVPFLIIIGDKEQQSGEVAVRTREGKDFGSMPLNSFISLLDEAIALKGRSGVS
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASA1_VERA1
Sequence: MGITLPSHDRLPRAPCTPTSSARTMPETPHPRTILRGHKAQVHALAFVGNNDRLASGDAEGYVALWDLTIMRPTAVWQPHDNAILGIQGWGADRIITHGRDHKLAVWKLATSDEANLSKKLPLDDTSEPRPQPWLLHLIDVNTMNFCAFAACVPTDPPPAGDDPELLLAVPNTLASESIDIYHLPTQTRRHTVKSPGQNGMVMALALVPQGDSLTLLAGYENGVTTAMHLSAASGTWNTTYRTQPHSQPVLSLDVSPDGLSFVTSSADAVVARHPVPPPAGMEVLEQPLKVVNTKHSGQQSLRFRDDGRVFATGGWDAMVRVYSGKTMKEVAVLKWHEVGCYAVAFASALKAPQAAGGVEERDGTVVRRAGEVSVRERRIAHAEAAHWLAAGSKDGKISLWDIF
What is the function of this protein?
Component of the ASTRA complex involved in chromatin remodeling.
What are the official names of this protein?
ASTRA-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat ASA1 family.
What are the subcellular locations of this protein?
Nucleus.