PharMolix/UniProtQA huggingface dataset:
Protein: OBG_MYCLE
Sequence: MPRFVDRVVIHTWAGSGGNGCASIHRSKFKPLGGPDGGNGGRGGSVVFVVDPHVHTLLDFHFRPHITAPSGKQGMGNNRDGAAGADLEVKVPDGTVVLDEDGRLLADLVGAGTRFQAAAGGRGGLGNAALASRTRKVPGFALLGEQGESRDLTLELKSVADVGLIGFPSAGKSSLVSVISAAKPKIADYPFTTLVPNLGVVSVGEHAFTVADVPGLIPGASAGRGLGLDFLRHIERCAVLVHVVDCTSVEPGRDPILDIAALEAELAAYTPTLQGDTTLGDFAERPRAVVLNKIDVPDARELAEFVCDNIAAERGWPVFSVSTVTRENLQSLIFGLWQMISAYHAARSEPAPGRSLIRPVPVDDSGFTVEPDGQGGFVVTGTRPERWIHQTNFDNAEAVGYLADRLARLGVEDELLRVGAQPGCTVSIGGMTFDWEPQKPAGHPVAMSGRGTDARLESTDPVGTAERKVARHQRHKHGG
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VG09_GAHVM
Sequence: MVNRRNYNYSMINQTCRVRNPARKARARLVLLQTGTWIFVPFPINVPVANIIHVPNTNIFVLTSSMILYFFRRFLFSRSASTSKSIYFASMRFREVLSVCLSPWSLWTRSKALISASPHFSPSSAHSASVFPCPASSATPARPSAPFPPWGAGATQDAVSPSCSASNSITPCRSCTRGRAKRAVRAERQGWLWVEDEKQIAVVGHEWREGAICDAERVKLCYKEKRWVGNIIKQPKWYIKTKNTYTVTPPIRRRSSKRLTTGTRRCRSIQVSLFCDLLSYTAAFRPTRASRTATRGHKKLRFLYGWAYRLLELSRDVYANEQCERVSVRTANQ
What are the official names of this protein?
Uncharacterized gene 9 protein.
Protein: GCH3_METVS
Sequence: MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHKGLAFYTRFDNIIAITNGIDLETHRRIQNSIKNRYPFTVSMAIASAETPYDAQKLATEKLQEYGSAQDEVRKEVLDIANEFVSNGYVQLAHVDINDITGTLTDLETAYDTYLSVQMTKLKLMEELKKYNSMGFFIGGDNFMCPCNGMNEKDFQCMFEDIMESSGIELKAGIGIGKTAEDASNLADIGLEIIREGKTDLQVYKLKQATGETKSSPYNYMCPI
What is the function of this protein?
Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP.  Also has an independent pyrophosphate phosphohydrolase activity.
What are the official names of this protein?
GTP cyclohydrolase III.
What is the protein family that this protein belongs to?
Belongs to the archaeal-type GTP cyclohydrolase family.
Protein: QUEC_SYNP6
Sequence: MAKAVVLLSGGLDSATAAAQAIADGYEAIALSFRYGQRHVRELEAARSVAAALGINQHFFVDVNIAQWGGSSLTDAAEPLPGSGVVAGEIPSTYVPGRNTVFIALALSLAEAQQASAIYLGINAVDYSGYPDCRPDYLAAFQQLASLSSKVGVEGQAPQLVAPLIHDHKVDIVRRAVVLGVPIPATWSCYAGGAEACGRCDSCRIRDRALIEAGYPEWATAIGRSLVSLQP
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RL13_DEIGD
Sequence: MKTFVPKNNEQNWVVVDAAGVPLGRLATLVASRIRGKHRPDFTPNIIQGDFVVVVNAEKVVLTGNKLDGKVYTRYTGYQGGLKTETARQALAKHPERVIEHAVFGMLPKGRQGRALHSRLKVYAGTTHPHAAQKPQQLEVRTALEVK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: Y1610_DICDI
Sequence: MDKNNNNNNSNGGHENLFKDLQNQKRVQNPSFSSGQSRTVPSISARGVAPISSSSSSSSISTTNNTTTTTTSGTGSTSSPVSKGVPLIPIGASRFKQQPSTDVWRSARGQQLSESLWSSFKQALQNSQNSQQSLSQSLSQSHSTNSEINNILLEFVKHYNSEYDKWNVEMGVDYANTKVYGIKLYCTPVLDIQTTLYLTRQLCSYVLNLSKALTDDNLDIPDGLHFICLINILSRSPLNSTLLHQENALAHPFQAARLASYKLSSFRDKNNPSFTKWWPYLKVLLANCCQIATNFVHDKQNLSFNSLRYGNVNNNNNSNNNNNIVNSTSLSSGSLLSNGGGISTSEPEISPSTSPLTGTTPTSPSSSWSSSSITNHQIQHQILMQQQQQQQAQQQHTQQYFNTIGQSSSYSYTNVINGVSTNNSTITATTTSNFLIQHIFKLGTISILMDSLQFFNDFFKTLQPKDSEDSFRLLIIDTLGILISGNGGLTTTTTTTTTTTTTTATSTNTTPNTIINNTTINNSGLTNSINNNNGGNNNLNKLKEPGNEIKTIINCIGMKAYIKTSKKVTSLQNEFQFQLHVIRVIKELISNNLNNAKYFNSHRGFEKIQEVILWVTQCFKPTDSHTFTDESCLDFDTSMPAQELSALLIGATSSNSSNNLPNLTNSISSPSHSSSSSSSTTTNINNSNNNTATATTTTSNVIIPPTMYDSLNSVLNSLKYTTYSEKSSSLIKSPPIIVKRSKVVQLSQLFQVLHSFSFTLVPFSKIQTNSSSSSGNLNYNIYSSSSASFINNNNNNNNCNISSPTNQSVNNNNNNNNNNNNNNNNNNNNNNNNVLPRSNSSYSIFRRGDSLNTIIDINQDNNNSNSNSNNSSTLDILNNSQDTIVDNNNGSNIDFEATITTNTTTVVTATVNLTNNNNNNNNNNNNMIDGNTEVTGGSAHNSWSSYTNINEQFQQLSLTSSTTATGSSPTSPTAFQYQSKPIDKMFVNTLLIETIFEKLFSQLNLSALNENHSTTSSLPISQNLSDDSSNTNTNNNNTSFGKIYISDNLQQNPNTDKSLSCGKIFNKIKNSTPELQLQIIEYLIKLVIENPYCLPILRRFNLWELIFSDNFYYSSPQATLNDDDIEYLLNSTTTTTTSSSTNISEEQLKKRKLYLFNGLRLGCLGLIQFFSTFNNRDNFEEICIILTEMRKSLLKSPASVIELCQLLINITKSNPQGTIQSLIKLRIFQQIPQMIQVLFKYEQASNSQFGLLHKKARNIIFSYLGQLIVHEELSYHAVVEKELIDVLFLLLRKVETKTFSITQIFFLMKLNVSSSSPSVTTLLSSSSQVLNSYQQQQQQPQQQSSQPQQQSSQPQQIPQSQLQQQNQTQSLQSSSLSSTSLLLTSQHQQPSTSLLSTSQFSSSSSLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQLLQQTQQQQQQQQQQQQQQVQTPSSPQTLASLLGNSSSNTLTSSSSTLSLNESSTLSRLPTSNNLSELYRTYISELSMIKEETSCTYDFKFD
What are the official names of this protein?
Putative uncharacterized protein DDB_G0281251.
Protein: NECT3_DANRE
Sequence: MALTMTAHFLRNNPIQLGLNLRVLLMLSFVSGLVYGSQVIVPPKVNAVLGKNVTLSCRVQVDTNLSLTQSSWERKLPNGWVTLAVYNPMFGISIPPDYERRLSFRSPSALDATIMLEDVGFADIGVYTCKVATFPLGNTQASTTVSVLVEPKVYVSAGSSALIDGGNETTVATCIAERARPPADVSWETNLYGMSEAHMQEDANGTTTTQVHYIWQPSRHAQGHTLTCVVKHPALQSDFRIPYIINVQFAPDILVLGYDGDWYVGRENVQLKCRAKANPPAQHFRWIRLDGEMPNGAERVNNTLVFTRPLQKNDSGVYRCEVANDIGLHSRDIRIRIQDPPSTTTMPPTTPVRLLTADISATAPGNKQRALITSPTLAPLHEGSLGTIVGGAVGGALFLLLLLILAGVYYQRQRRTFRGDYYTKQYHGPSDMQKAPQPHELQQVYSKGSPDTKLKSNQDNGTIYPDKDREEWGDFDRERSPNGRSRALREAGQLNHHNHQNHEHGFHSNHHTGHPQSYSPAHHIQRSSLQPQPRRYPAPQVMSNGSPYLPEDCYDNEYVSHTDGSMISRREWYV
What is the function of this protein?
May play a role in cell-cell adhesion.
What are the official names of this protein?
Nectin-3-like protein, Nectin cell adhesion molecule 3, Poliovirus receptor-related protein 3-like.
What is the protein family that this protein belongs to?
Belongs to the nectin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YOBD_ECOSM
Sequence: MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LPXB_PROM3
Sequence: MVRLLISTGEVSGDLQGSLLIQALQREVERRSLPLELMALGGPRMQASGAELLADTAPMGAIGLWEALPLVLPTLRLQSRVDHVLKQRPPDAVVLIDYMGANVRLGHKLRRWFPRVPIIYYIAPQEWAWRFGDGGTTQLLSFTDRILAIFPVEAEFYAQRGAKVTWVGHPLLDTVSVLPDRQLARERLGLKSGQRLLLLLPASRQQELRYLMPTLAKAAALLQQRDPSLEVIVPAGLASFETSLQKALEAAAVRGRVLSAQQADELKPMLYAAADLALGKSGTVNMELALRGVPQVVGYKVSRITAFVARHFLRFRVDHISPVNLLLKERLVPELLQDEFTAEALVQAAIPLLEDPAQRHEMLEGYWRLRQTLGVPGVTDRAAKEILDLTKP
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: YJN2_YEAST
Sequence: MSIISSWLLVSIICLTTSIVTKLQAAGVTTHLFYLTRGAPLSLKENYYPWLKAGSFFPDALYSCAPSNKDWSDFAEFTHWPNFLMIAVSYWQQKYGQNDRLRGTHGSLALKSFLIGVFTHQIVDVSWHSLVTDYRMHGLLRVLSETEFDGDIETAHTFLDVMGEFLTLNNVIRDSNNNENWDFLTRSDWKLPREEDLMEIIRNAGLSKEKLSYAELEFCVKRGMAAAISEGYLFRSQRNQLLTNIYSTSPRANDLILNHWLGGQSNLVAMLQRCVPFFETLFHDENTNEAQAEELRLCANLPPVSQKRINARPLVSSLKARKGNSHIVVSPMKSFSDFGTSLTMGKFREDNKDYLAVSAPLEDTVGAIYIVPWDILTVARKEDFSILQPITAMYGSKVGTYKASDVDYLLVSQPGTCTIDFYFKGVKILTIKDETTEEAHQLQFAVTGNFYDDKIPDLVVSSPSYGANETGIATFIPGSSIISYLTNSDKYQVVDISTFKGVINLDGYPMKIPFQHFGATIQISDTTDKQKLIYITCQSLGTVFVYSSNDLHDLSIPIYYITKNGVIPAKDSDHVEWHIIPSKEHGMFGAAIYSWNFEGMSFVAVSQPMFDTVFIYIEKSGQIEFFLKLVLKIKTKSDSIPDEFGSSLLFNDEEKKLYVSSPGSFDARGSIWKISMDELLKAGNDPKRKTLLINNLRHLMLINPDKSSKGVSNFGNSMILGPQNHLIVGIPQYGYGNFDHMQLTGRILVL
What are the official names of this protein?
Uncharacterized protein YJL132W.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MT_BARBB
Sequence: MDPCDCSKTGTCNCGATCKCTNCQCTTCKKSCCSCCPSGCSKCASGCVCKGNSCDSSCCQ
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: DAPB_MANSM
Sequence: MTLKLAIVGAGGRMGRQLIQAVQAAEGVELGAAFERKGSSLIGADAGELAGLGELGIKVAEDLAAEKDKFDIIIDFTRPEGSLEHIKFCVANNKKLILGTTGFDDAGKQAIGKAAEKTAIVFASNYSVGVNLVFKLLEKAAKVMGDYSDIEIIEAHHRHKVDAPSGTALSMGEHIAKTLGRDLKVNGVFSREGITGERKRTDIGFSTIRAADVVGEHTVWFADIGERVEISHKASSRMTFANGAVRAAKWLANKQIGLFDMTDVLDLNNL
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SG1D4_HUMAN
Sequence: MRLSVCLLMVSLALCCYQAHALVCPAVASEITVFLFLSDAAVNLQVAKLNPPPEALAAKLEVKHCTDQISFKKRLSLKKSWWK
What is the function of this protein?
Seems to be involved in the regulation of chemotactic cell migration and invasion.
What are the official names of this protein?
Secretoglobin family 1D member 4, IFN-gamma-inducible secretoglobin, IIS.
What is the protein family that this protein belongs to?
Belongs to the secretoglobin family. Lipophilin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KGUA_MESH2
Sequence: MKVKMSKLIILSGPSGVGKGTIESLLLKNKNLLIKLAISATTREKRRDEINGVNYFFLTVQEFKEKIENDEFIEWSCHFNNYYGTLKSQIKFIQSQNFIPLLEIDTTGAKNIIENYKNKGELSQLLTIFILPPSIESLKNRIQKRLTETNIQINQRLEKAKAEIKIKNLFKFQVVNDNLEECVAQIEKIISKEIQKT
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_THEGJ
Sequence: MAIRIYNTLTRQKEEFKPLHEGEVRMYVCGPTVYDYPHLGHARTYIAFDVIRRYLEHKGYTVLMVMNFTDIDDKIIKRANETGEDPKELAEKFLRIFLEDMKALKVKPADIYPRVTEHMQDIISFIKKLQEKGYAYEGSDGVYFEVRKFKDYGKLSKIKLEDLVKGARVEPGEGKRNPEDFALWKKAKPGEPKWESPWGEGRPGWHIECSTMSSKYLGESFDIHGGGNDLIFPHHENEIAQSEACFGHEWVHYWMHTGFLMVNGEKMSKSLGNFVTVRELLKRYNPEVIRLFVLQRHYRSPLDYSEEGIEHAKNNLERLYNTLENIRVAMSKAEISFRWDEPEFRAYEAIRDARKKFYEAMDDDFNTAEALKAVFEVSNAINRYLTEVEKPKESILRKAWEFFKDVGEVFGLFEDYFKEQKAENDEELINLLVEVRAQLRKEKKFDLADKIREELRKLGIQLEDTPQGTVWKRIKV
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMH_MYCAP
Sequence: MTKIKIVAVGSLSPKFKSLDEEYAKQVGHFCSLSLSELKEFSEEKNIEVKKEKETKLILDALMPNSKVILLSLKGKQIDSIAFSKLIEMNTNQSFTFIIGGSDGVCEEHFESAQKLSFSQMTFPHQLFRIMLIEQIYRAFMILNNSKYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHS_COLP3
Sequence: MTVQSNNKLASQVCEACHVDAPKVSDEELKELIGLIPDWVPQVRDNVMMLEREYKFKNYKLAWAFANKVSELAESEFHHPSILLEWGKVTVTWWTHSIGGLHKNDFICAAKTDQLGD
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: PYRF_DESVM
Sequence: MAELVIALDYPTMDAALATARALRGATDTAGDAGGRLWMKVGLELFTASGPEVVARLKDMGFPVFLDLKFHDIPNTVRGAVRSAVATGADMCNIHLPGGERMCRAAVEGLAEGAAARGHGAAPILLGVTVLTSVAPGELPGGADPSAEAARLAVCGREWGLGGVVCSGYEAAGIKQRCGRDFICLTPGIRPAAPQRSGSGDDDQRRVMTPAEAVRAGSDYLVVGRPVTGAAGPDGPAEAARRILAEMRGA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RPOZ_NITHX
Sequence: MARVTVEDCIDKVDNRFDLVLLAAHRARMISSGSQLTIDRDNDKNPVVSLREIAEQTISPEDMREELVHSLQKFVEVDEPEPDTVPLIGSAGASVDADDTEVAVERMTEEELLKGLEGLAPREEQPEEDE
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: TWME_TALWO
Sequence: MTPTTLPTSQRAVQQDGNGKLHVANNAAIPSLLPGHVLVKTYAVALNPSDYKIQKNFPIPGAYVGIDFSGTVVQVANDVDSINPGTEVFGAAFTFSSAHRLANGAFAEYVRVRADLLFRIPSEQQCQNDGDLTLFKAATLGTAMSTCLLSLWSPDALGLVGKPEEPVLSEKPIPVLVYGGSTSVGTIAIQLLKLSGYDPIATCSPRSFDLVRSRGASNVFDYSSADVALKIKTHTGGRLKYALDCISDVASVATCYAAIQRPGGRYVSLEYIPDELLAQRRAVRPNFVLSAELYGEEIVLGEEAYDRPANREKHQLAVQNVGMLQRLIDSGGLKTHPTEEIEGGLEGVVKGLVALAGGGHPRKLVAVV
What is the function of this protein?
Trans-enoyl reductase; part of the gene cluster that mediates the biosynthesis of wortmanamides A and B, reduced long-chain polyketides amidated with a specific omega-amino acid, 5-aminopentanoic acid (5PA) (PubMed:29343058).  The PKS modules of TwmB are involved in the synthesis of the polyketide backbone, whereas the non-canonical C domain of TwmB is a bonafide condensation domain that specifically selects 5PA and catalyzes amidation to release polyketide chain (PubMed:29343058).  The C domain clearly prefers C16 and C18 fatty acyl substrates, which is consistent with simultaneous formation of both octaketide and nonaketide acyl amides wortmanamides A and B (PubMed:29343058).  Because TwmB lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase TwmE (PubMed:29343058).  The roles of the remaining enzymes have still to be clarified (Probable).
What are the official names of this protein?
Trans-enoyl reductase TwmE, Wortmanamides biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
Protein: CCAC_AMPCA
Sequence: XFENERGVADPVGFFDPLGFTADGSVENFKKLAQTEIKHGRVAMLATMGYITQEITGKLPGYLSPSTGVKYDDDINGVLGLIKIVPAGLWGIMIFYAALSLA
What is the function of this protein?
The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated.
What are the official names of this protein?
Caroteno-chlorophyll a-c-binding protein.
What is the protein family that this protein belongs to?
Belongs to the light-harvesting chlorophyll a/b-binding (LHC) protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: PYRD_PSYCK
Sequence: MSYALLRPFLFNMDPEHAHEMTLSLLDKAHKARVLGLVYGQSMQPTDCMGLQFSNPVGLAAGLDKNGDYIDALAELGFGFIEVGTVTPKPQAGNDRPRLFRLKQADAIINRMGFNNEGVDYLIENVQRCKYKGNIGINIGKNAATPVEKAADDYVYCLERVYPHASYITVNISSPNTANLRDLQSGEALTHLLDAIKNRHSQLATEYGFYVPLVLKVAPDLDPIQVDYISQQLLDFEIDGLIATNTTLSRVGVEDLPDGDQAGGLSGRPVSHISTQILQQFSDQLDGKVALIGVGGIDSGAKAVKKIEAGADMVQLYSGLIYKGPGLVQSCIQSIGGYYDAMEN
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PSDE_HUMAN
Sequence: MDRLLRLGGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLNKPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVVKEMLELAKNYNKAVEEEDKMTPEQLAIKNVGKQDPKRHLEEHVDVLMTSNIVQCLAAMLDTVVFK
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  The PSMD14 subunit is a metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains within the complex.  Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation.  Also involved in homologous recombination repair by promoting RAD51 loading.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 14, 26S proteasome regulatory subunit RPN11, 26S proteasome-associated PAD1 homolog 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M67A family. PSMD14 subfamily.
Protein: PNP_ACIC1
Sequence: MADHDVHTAEAVIDNGSFGVRTVRFETGRLARQAGGSAVAYLGDTMVLSATTASKEPREQFDFFPLTVDVEERLYAAGRIPGSFFRREGRPSEEAILTCRLIDRPLRPSFVKGLRNEVQVVVTVLAVDPEHLYDVVAINAASMSTLLAGLPFSGPIGGVRMAHIDGTWVAFPTYSELERATFDMVVAGRVLPDGDVAIMMVEAEATEETIPLIREGAPAPTEEVVAGGLEAAKPFIRTLCAAQSELAARAAKPVTEFPLFRDYEDDVYDAVAATVRDDVARALTIAGKQEREAALDEVANTALGRLGERFAGREKEILAALRALTKKLVRERIIREKVRIDGRGLTDIRPLTAEVGIVPRVHGSALFERGETQILGVTTLNMLRMEQQLDTVSPRTKKRYMHHYNFPPYSTGEVGRVGSPKRREIGHGALAERALIPVLPSREEFPYAIRQVSEAIGSNGSTSMGSVCASTLSLLNAGVPLRAPVAGIAMGLISDTVDGETHYVTLTDILGAEDAYGDMDFKVAGTRDFVTALQLDTKLDGIPASVLAAALPQAREARLTILDVMAKAISEPAPMSPYAPRIITIKIPVDQIGAVIGPKGKIINQIQDDTGAEITIEDDGTIYIGATEGTAAEAARAAISAIANPQLPEVGERYLGTVVKATPFGVFVSLLPGKDGLLHISELRKMAGGRRVENVEDVLKVGDKIQVEIRDIDARGKLSLVPVDVPGAVLAEDAGAGESAASGGAPRSAGGPQPREHQGPGRPRGRGGDHGGEGRQRTRRRH
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_ALBFT
Sequence: MAAKLSFSDLWSDVCAVRDRSPLVHSITNLVVINFNANVLLAAGASPVMAHAHEEVADMVGIAQALVLNIGTLDPYWIESMQLALRAAAKRGIPVVLDPVGAGATKYRNEAIEQLLMTSLPTVVRGNGSEIMSVAGSAAQTRGVDSSAAATDALGAAQSLVQRTQGVVCVSGQIDHILDASHRWAQLSNGHAWMTRITGVGCSATALIGAFCAVQPDAWRATVAAMALLGVVGEVAAEKVIARGKGVGSLQMALLDELQLLDQGTFEQRLKLEVAQW
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: METK_PELUB
Sequence: MSNLKNFLFTSESVSEGHPDKVSDRISDMVVDSFLSGDPFSRVACETLTTTNKVVLAGEVRGPSIKEEDLIQKVRECIKDIGYDQDGFTWREATKIESHLHAQSADIAMGVDSSSNKDEGAGDQGIMFGYACNETEELMPAPIHYSHKILRLMAEDRKSGKLKNIEPDSKSQVTFEYVDGKPTKVKSVVISSQHSADVDQAKVRELLKPYLLKSIPEKFLKDFNEEELYINPTGNFVIGGPDGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPTKVDRSAAYAARYIAKNIVASNIAEKCLIQLAYAIGVSKPLSIYVDLFDNDLEKNKFVTEKISENFDLSPRGIREMLGLNKPIYEKTAAYGHFGRVPEANGSFSWEKTDKKDVFSK
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPG_SALA4
Sequence: MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRVELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVLVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRT
What is the function of this protein?
Rhomboid-type serine protease that catalyzes intramembrane proteolysis.
What are the official names of this protein?
Rhomboid protease GlpG, Intramembrane serine protease.
What is the protein family that this protein belongs to?
Belongs to the peptidase S54 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GREA_STRGC
Sequence: MAEKTYPMTLAEKEKLEKELEELKLVRRPEVVERIKIARSYGDLSENSEYEAAKDEQAFVEGQISSLETKIRYAEIVDSDAVAKDEVGIGKTVTIQEVGETEKEVYIIVGSAGADAFAGKVSNESPIGQALIGKKKGDIATVETPVGSYDVKILKVEKTK
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: MFNA_METM7
Sequence: MDEQDILKELRKYRSQDLKYEEGYILGSMCTKPHPMARKISEMFFETNLGDPGLFKGTSKLEKEVVSMLGGILHNNNAFGYIISGGTEANLTAMRAFKNISKSKDKQQNIIIPETAHFSFDKARDMMDLNVVRPPLTEYFTMDVKFIRDYIEDSKNEISGIVGIAGCTELGSIDNIYELSKIAVENDILLHVDAAFGGFVIPFLDDKYKLKGYNYDFDFSLNGVSSITIDPHKMGLAPISAGGILFKNNTFKNYLDVDAPYLTEKQQATLIGTRSGVGVASTWGIMKLLGIDGYKKLVNESMEKTMHLVKKAREYGFETAIDPVMNIVALKDEDKHDTCMKLREENWYVSVCRCVEALRIVVMPHLEIEHIDGFLESLSNTKKY
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: Y2030_CLOP1
Sequence: MNNDLQPIVLVDEEGIETTFNVVTKLDIEEKEYFLLSPEGEEDVVIAMQVVQDEDGEETLAPVENDFEIEMIEEAYATLFAEEE
What are the official names of this protein?
UPF0473 protein CPF_2030.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.