PharMolix/UniProtQA huggingface dataset:
Protein: SRS11_HUMAN
Sequence: MSNTTVVPSTAGPGPSGGPGGGGGGGGGGGGTEVIQVTNVSPSASSEQMRTLFGFLGKIDELRLFPPDDSPLPVSSRVCFVKFHDPDSAVVAQHLTNTVFVDRALIVVPYAEGVIPDEAKALSLLAPANAVAGLLPGGGLLPTPNPLTQIGAVPLAALGAPTLDPALAALGLPGANLNSQSLAADQLLKLMSTVDPKLNHVAAGLVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKECSVEKGTGDSLRESKVNGDDHHEEDMDMSD
What is the function of this protein?
May function in pre-mRNA splicing.
What are the official names of this protein?
Serine/arginine-rich splicing factor 11, Arginine-rich 54 kDa nuclear protein, p54, Splicing factor, arginine/serine-rich 11.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family.
What are the subcellular locations of this protein?
Nucleus. Note=Colocalizes with spliceosome components.
Protein: NANK_ESCF3
Sequence: MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALREALAALVSPLQAHAQQVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTDLPTIAINDAQAAAWAEYQGLEGDITDMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLADPHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADAKAIFKRVGQGDEQAQQLIHRSARVLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL
What is the function of this protein?
Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P.
What are the official names of this protein?
N-acetylmannosamine kinase, ManNAc kinase, N-acetyl-D-mannosamine kinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family. NanK subfamily.
Protein: MODC_ECOL6
Sequence: MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDADKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMAKSMVNQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLEEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NDF4_MOUSE
Sequence: MAKMYMKSKDMVELVNTQSWMDKGLSSQNEMKEQERRPGSYGMLGTLTEEHDSIEEDEEEEEDGDKPKRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIETLRLARNYIWALSEVLETGQTLEGKGFVEMLCKGLSQPTSNLVAGCLQLGPQSTLLEKHEEKSSICDSTISVHSFNYQSPGLPSPPYGHMETHSLHLKPQPFKSLGDSFGSHPPDCSTPPYEGPLTPPLSISGNFSLKQDGSPDLEKSYNFMPHYTSASLSSGHVHSTPFQTGTPRYDVPVDLSYDSYSHHSIGTQLNTIFSD
What is the function of this protein?
Probably acts as a transcriptional activator.  Mediates neuronal differentiation.  Required for the regulation of amacrine cell fate specification in the retina.
What are the official names of this protein?
Neurogenic differentiation factor 4, NeuroD4, Helix-loop-helix protein mATH-3, mATH3, Protein atonal homolog 3.
What are the subcellular locations of this protein?
Nucleus.
Protein: MNTP_XANC8
Sequence: MSPLSIVLLGFAMSTDAFAAAIGKGAAMRRPRWRDAVRAGLVFGCIEAITPVIGWMLGRAASDYLAAFDHWIAFGLLGALGAHMIVAGLRNESEVDEALRDTPKRYGLLALAATGFATSIDAMAVGVSLAFLDVHIGVVAAVVGLCTLSMVTAGVMLGRALGALIGKRAEILGGVILILIGSTILYEHLSGAA
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LRP_SALTY
Sequence: MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNAAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
What is the function of this protein?
Mediates a global response to leucine.  Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons.  For example it is regulator of the branched-chain amino acid transport genes.
What are the official names of this protein?
Leucine-responsive regulatory protein.
Protein: SYC_STAS1
Sequence: MITLYNTLTRQKETFEPIEPGKVKMYVCGPTVYNYIHIGNARPAINYDVVRRYFEYQGYEVVFVSNFTDVDDKLIKRSKELDESVETIADRYIDAFYEDVGALNVKKATSNPRVMNHMDDIINFIKDLVDEGYAYESGGDVYFRTRKFQDYGKLSHQSLNDLKVGARIEQGEQKEDALDFTLWKQAKPGEISWESPFGEGRPGWHIECSVMAYHELGATIDIHAGGTDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFVLVHDIIKQIDPDVLRFFMISVHYRSPINYNMELVEAAKSGLERVRNSYQAIEEREAIATDIEAQSDYIAEIDKILEQFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTKVLGRFKEVYQIFSDVLGVPLKGKDSDELLDEEVEALIEERNNARKDKDFARADEIRDQLKEQNIILEDTPQGVRFKRG
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECR_STRP3
Sequence: MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSNEDVNDFAKNLLAAKRELTYCSICGNLTDDDPCHICTDTSRDQTTILVVEDAKDVSAMEKIQEYHGYYHVLHGLISPMNGVGPDDINLKSLITRLMDGKVSEVIVATNATADGEATSMYISRVLKPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: RL10_FRATN
Sequence: MALRIEDKKAIVAEVAEQVSSALSAAVADYRGLTVNEMTSLRKQARESGVYLRVVRNNLARLAIKGTEFECLADALKGPLVLALSKDEPGAAAKLFKNFQKDHNAFEVKNLAMSGELFGPEKLDDFAKLPTREEALATLLNVMQAPVTKFVRTLNEIPSQAVRVFAAVGDSK
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: RNH_PECCP
Sequence: MRKQVEIFTDGSCLGNPGPGGYGALLRYKQHEKPLSAGYRLTTNNRMELMAAIAALETLTTECDVVLCTDSQYVRQGITSWIHNWKKRGWKTADKKPVKNVDLWQRLDTAIQRHSVRWEWVKGHAGHPENERCDELARAAAGAPTLDDTGYQAE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_SHEPC
Sequence: MELVLKDAQSALEVSETTFGRDFNEALVHQVVVAYAANARQGTRAQKTRAEVTGSGKKPWRQKGTGRARAGSVKGPIWRGGGVTFAAKTQDHSQKVNKKMYRGALKSILSELVRQERLVVVESFGVEAPKTKELKAKLKAMNLEDVLIVTAEVDENLFLAARNLYKVDVRDVAGLDPVSLIAFNTVLVTADAVKQIEEMLA
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: MNHC2_STAAT
Sequence: MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIMSMGTYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKEDEIEGLRGEDDAK
What are the official names of this protein?
Putative antiporter subunit mnhC2, Mrp complex subunit C2, Putative NADH-ubiquinone oxidoreductase subunit mnhC2.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISPE_ACIBT
Sequence: MIRVPSPAKLNLFLHITGRRENGYHELQTIFQLIDLYDWMTFTPISEDEIQIEGLGEVQLEQNLIYRAAQILRPHAQNPCGLHIKIEKNIPMGAGLGGGSSNAATTLIVLNQLWQCGLTEEQLAQFGVKLGADVPIFIYGLNAWAEGIGEHLSFIDLDQKQFIVLKPDCFISTQLLFSQKTLTRDSKPTTFCAYQLEPSNFGNNFEPLARELYPEVEEAMQYLDQFGHAKLTGTGACVFAEVTDEMNVDDILKHAPCKAYLVHSLKESPLRHFKVAS
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: EF1B_ARTSA
Sequence: MANIDLKAEKGQEQLNELLANKSYLQGYEPSQEDVAAFNQLNKAPSDKFPYLLRWYKHISSFSDAEKKGFPGIPTSASKEEDDDVDLFGSDEEDEEAEKIKAERMKAYSDKKSKKPAIVAKSSVILDIKPWDDETDMAEMEKLVRSVQMDGLVWGAAKLIPLAYGIKKLSIMCVVEDDKVSIDELQEKISEFEDFVQSVDIAAFNKV
What is the function of this protein?
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.
What are the official names of this protein?
Elongation factor 1-beta, EF-1-beta.
What is the protein family that this protein belongs to?
Belongs to the EF-1-beta/EF-1-delta family.
Protein: EX7L_YERPN
Sequence: MSQSSASSIFTVSRLNQTVRELLEREMGQIWLTAEISNFSQPASGHWYFTLKDDRAQVRCAMFRNSNRRTTFRPQNGQQVLVRASITLYEPRGDYQLIAESMQPAGDGLLQQQFEQLKQQLAAEGLFDQSHKQPLPHPAKQVGVITSASGAALHDVLHVLQRRDPSLPVIIYPTSVQGVDAPLQIVRAIQLANLRAECDVLIVGRGGGSLEDLWSFNDERVARAIFNSHIPIVSAVGHETDVTIADFVADLRAPTPSAAAELVSRNQIELVRQIQGQQQRMEMAMDYYLAQRNQQFTRLEHRLQQQHPHLRLARQQTLLLKLQRRLEESAQTQIRLLSKRTERLQQRLQQVQPQGQIHRYNQRVQQQEYRLRQAVERQLNGYRQRFGIACSQLEAVSPLATLARGYSVTQTPAGALLKTTKQVQAGDKLTTRLQDGWVESEITQVTVAKKSRQKKVVTQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMOA_SHESW
Sequence: MNTSQDTIYAQPNEHISDFQFDNRVAGVFSDMIRRSVPGYTQIINTIGDFADRFVMPNTQIYDLGCSLGAATLSIRRQIQGRQCRIIAVDNSESMVARCQENLNAYVSDTDVDLVCGDIRDIDIQNASLVVLNFTLQFLPPEDRETLIAKIYQGLNPGGMLVLSEKIRFDDAPIQTLLEEQHLDFKRANGYSELEISQKRSALENVMKPDTLTTHQQRLTRQGFSHFSLWFQCFNFASMVAIK
What is the function of this protein?
Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
What are the official names of this protein?
Carboxy-S-adenosyl-L-methionine synthase, Cx-SAM synthase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
Protein: NDHH_SYNJA
Sequence: MPMIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEAITVNAVEKLAGIPVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVGGVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGIGVISKQDAINWGLSGPMLRACGVNWDLRKVDHYECYDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANFKIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.  Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase subunit H, NDH-1 subunit H, NDH-H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RADB_METS3
Sequence: MKVLANFEDNHKIPTNSGIDNLLDGGVEKGTVTQIFGPPGSGKSNISLVLAVNVAKQGKKVVYVDTEGGISINRIKQIAGEDFPKIVNNIIVFEPTSFLEQNENLKTIELWIRKHHDDVDLCVLDSAVALYRVDDMKSSRLNKELGKQMGILAKIARNYDVAVVLTNQIYSSFDDDNKDVVKAVGGTILQYWSKTIIQLERNDEFNKRVATLKRHRSIGEGKQATFKIVERGII
What is the function of this protein?
Involved in DNA repair and in homologous recombination.  May regulate the cleavage reactions of the branch-structured DNA.  Has a very weak ATPase activity that is not stimulated by DNA.  Binds DNA but does not promote DNA strands exchange.
What are the official names of this protein?
DNA repair and recombination protein RadB.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic RecA-like protein family. RadB subfamily.
Protein: OAT_EXISA
Sequence: MSKTHDVIELTEKFGAHNYHPLPIVISEAKGIWVTDPEGNRYMDMLSAYSAVNQGHCHPKIIQALKDQADKITLTSRAFYNDQLGRFYDKVVTLTKKQMVLPMNTGAEAVETAVKTARRWAYDVKGIPGQAEIIVCSGNFHGRTMAAVSMSTEAEYQRGFGPLLPGFKVVPYGDIDAFEAAITENTAAFIVEPIQGEAGIIIPPAGYLKRASELCKEHNVLFVADEIQSGLGRSGKWFAIEWEDVTPDMYILGKALGGGVFPISCVAADQEILSVFNPGSHGSTFGGNPLASAVSVAALEVLEEENLPERSLELGTYFMDRLKSIDNPMIRDVRGRGLFIGIELTESARPYCEALKERGLLCKETHETVIRLAPPLVITKEELDQAFEAIEAVLAPAAIS
What is the function of this protein?
Catalyzes the interconversion of ornithine to glutamate semialdehyde.
What are the official names of this protein?
Ornithine aminotransferase, OAT, Ornithine--oxo-acid aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX17_RAT
Sequence: MGAQPSRRRMTEAQHMALAELPPELLLQVLSHVPPRALVTRCRPVCRAWRDLVDGPSVWLLQLARDRSAEGRALYALAQSCPADRNGHDDFPLCALARFCLLAPLGRNLIYNSCGEQGFRGWEVEHGGNGWAVEKNLTMVPGAPSQTCFVTSFEWCFKRQLVDLVKEGVWQELLDSAQIEIYIADWWGARENCGCIYRLRVRLLDEHENEVVKFSASPNPVLQWTERSCRQVSPDCSLNPGLLQGLSRLH
What is the function of this protein?
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.  Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides.  Also recognizes sulfated glycans.  Does not bind high-mannose glycoproteins (By similarity).
What are the official names of this protein?
F-box only protein 17.
Protein: TRPA_STAAS
Sequence: MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGPVIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDTGVYGLIIPDLPYELSQRLKQQFSHYGVKIISLVAMTTDDKRIKDIVSHAEGFIYTVTMNATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIVKRFKSNTREEIIKYLQSIQQTLNN
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: STS1_NEOFI
Sequence: MNSLVATPPVPPHFYEYSRLSSPHPMSTPTHTPTNRKRKADDDGNDHDGRMSASPTNSPAFTPRSLPAPRSFKRSRPNVSGRPLSLPRLLETLDTDALRGILRSMCERHPALADEVIHTSPRPSVSSALQVLRNYQSTLQNSFPLGGNPESDYAYNRVRQPLGNLLDALSDFTPHFLPPHETQASVSLSYLDGATDIIHALPRWHSPQNNIERDSAYDEICKAWILVIREAAKRGGGIQLQYGGWDQKLAKHNQNAGGRLQAAVNELGNSLGWMHGPDSQGYGSSTGGDLVSVREQLLSGTYGLGTPVKVGPW
What is the function of this protein?
Involved in ubiquitin-mediated protein degradation.  Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates.  Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity).
What are the official names of this protein?
Tethering factor for nuclear proteasome sts1.
What is the protein family that this protein belongs to?
Belongs to the cut8/STS1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RPN1_PIG
Sequence: MEAPAVCLLPLLLLLWAWAPAPGRASPEALPLVNEDVKRTVDLSSHLAKVTAEVVLAHAGSSSSPRAASFLLALEPELEARLAHLGVQVKGEDEEENNLEVRETKIKGKRGRFFTVTLPVALDPGAKISVTVETVYTHVLQPYPTQITQSEKQFVVFEGNHYFYSPYPTKSQSMRVKLASRNVESYTKLGNPTRSEDLLDYGPFRDVPPYSQDTFKVHSENNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGISSIRSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRFPLFGGWKTHYIVGYNLPSYEYLYNLGDQYALKMRLVDHVFDEQVIDSLTVKIILPEGAKNIQVDSPYEISRAPDELHYTYLDTFGRPVIVAHKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFFTVIVYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRIGLYRHFDETINRYKQSRDVSTLNSGKKSLELEHKALTSEVALLQSRLKTEGSDLCDKVSEMQKLDAQVKELVLKSAVEAERLVAGKLKKDTYIENEKLISGKRQELVTKIDHILDAL
What is the function of this protein?
Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (Probable).  N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).  All subunits are required for a maximal enzyme activity (By similarity).
What are the official names of this protein?
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, RPN-I, Ribophorin-1.
What is the protein family that this protein belongs to?
Belongs to the OST1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Endoplasmic reticulum membrane; Single- pass type I membrane protein. Melanosome.
Protein: NU2C1_LACSA
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSLIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITSLLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATIGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATMKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNDGYASMITYMLFYISMNLGTFACIVLFGLRTGTENIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLYLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIIAIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 A, chloroplastic, NAD(P)H dehydrogenase, subunit 2 A, NADH-plastoquinone oxidoreductase subunit 2 A.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: RL28_ACISJ
Sequence: MARVCEVTGKKPMVGNNVSHANNKTKRRFLPNLQYRRFWVESENRWVRLRVSSAALRLIDKNGIDSVLADMRARGQA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: LIPA_FRATT
Sequence: MKEISGIKVKVESGSKYTTDHGFHAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVKSITKKHKLSTVCEEARCPNINECWSHGTATIMLMGSVCTRACKFCSVDTGNPKGWLDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTPDFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSPNVLTKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRKVGLEKGFLEVASGPMVRSSYRADRVFKRNNLDL
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ERPA_BURMA
Sequence: MNAVTESAATTEMPAPFVFTDAAADKVKQLIDEEGNPDLKLRVFVQGGGCSGFQYGFTFDEEVNEDDTVLNKNGVVLLVDAMSYQYLVGAEIDYKDDLNGAQFVIKNPNATTTCGCGSSFSV
What is the function of this protein?
Required for insertion of 4Fe-4S clusters.
What are the official names of this protein?
Putative iron-sulfur cluster insertion protein ErpA.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
Protein: OMPA_NEIMH
Sequence: MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNYQLQLTEAQAANGGASGQVKVTKVTKAKSRIRTKISDFGSFIGFKGSEDLGDGLKAVWQLEQDVSVAGGGATQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAIDPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPIQNSKSAYTPAYYTKDTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSGSDQAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKTKNSTTEIAATASYRFGNAVPRISYAHGFDFIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF
What is the function of this protein?
Serves as a slightly cation selective porin.  Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity (By similarity).
What are the official names of this protein?
Major outer membrane protein P.IA, PIA, Protein IA, Class 1 protein.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: WECF_ECOL5
Sequence: MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPKLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.
What are the official names of this protein?
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase, 4-alpha-L-fucosyltransferase, TDP-Fuc4NAc:lipid II Fuc4NAc transferase, Fuc4NAc transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 56 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL28_PROMP
Sequence: MSRVCELTGAKANNGMAVSHSHIRTKKLQQVNLQKRRLWWQEGKKWVNIKISTKALKSIQKVGLDKVAKTNGVDLNKF
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: ARC_MYCSJ
Sequence: MSESQRHEAREDGFTTPHESGLSSEDAAELEELRREAAALREQLENAVGPQSGLRSARDVHQLEARIDSLAARNAKLMDTLKEARQQLLALREEVDRLGQPPSGYGVLLASHEDDTVDVFTSGRKMRLTCSPNIDVKALKQGQTVRLNEALTVVEAGTFEAVGEISTLREILSDGHRALVVGHADEERIVWLAEPLVSVEHLPDNEVAGPELDDDRPRRLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYSDIGGLTRQIEQIRDAVELPFLHKDLYREYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAREAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIFSKYLTEELPVNEDDLAEFGGDRSLTIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKYAIKSVLETGQKGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSANRAIDTESNLGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Mycobacterial proteasome ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.