PharMolix/UniProtQA huggingface dataset:
Protein: RL14_FRACC
Sequence: MIQQESRLRVADNTGAREILCIRVLGGSGRRYAGIGDIIVGTVKDALPGAGVKRGDVVKAVVVRTTKERRRPDGSYIRFDENAAVLIRDGGDPRGTRIFGPVGRELRDKKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: CAR_SEGRC
Sequence: MTESQSYETRQARPAGQSLAERVARLVAIDPQAAAAVPDKAVAERATQQGLRLAQRIEAFLSGYGDRPALAQRAFEITKDPITGRAVATLLPKFETVSYRELLERSHAIASELANHAEAPVKAGEFIATIGFTSTDYTSLDIAGVLLGLTSVPLQTGATTDTLKAIAEETAPAVFGASVEHLDNAVTTALATPSVRRLLVFDYRQGVDEDREAVEAARSRLAEAGSAVLVDTLDEVIARGRALPRVALPPATDAGDDSLSLLIYTSGSTGTPKGAMYPERNVAQFWGGIWHNAFDDGDSAPDVPDIMVNFMPLSHVAGRIGLMGTLSSGGTTYFIAKSDLSTFFEDYSLARPTKLFFVPRICEMIYQHYQSELDRIGAADGSPQAEAIKTELREKLLGGRVLTAGSGSAPMSPELTAFIESVLQVHLVDGYGSTEAGPVWRDRKLVKPPVTEHKLIDVPELGYFSTDSPYPRGELAIKTQTILPGYYKRPETTAEVFDEDGFYLTGDVVAEVAPEEFVYVDRRKNVLKLSQGEFVALSKLEAAYGTSPLVRQISVYGSSQRSYLLAVVVPTPEALAKYGDGEAVKSALGDSLQKIAREEGLQSYEVPRDFIIETDPFTIENGILSDAGKTLRPKVKARYGERLEALYAQLAETQAGELRSIRVGAGERPVIETVQRAAAALLGASAAEVDPEAHFSDLGGDSLSALTYSNFLHEIFQVEVPVSVIVSAANNLRSVAAHIEKERSSGSDRPTFASVHGAGATTIRASDLKLEKFLDAQTLAAAPSLPRPASEVRTVLLTGSNGWLGRFLALAWLERLVPQGGKVVVIVRGKDDKAAKARLDSVFESGDPALLAHYEDLADKGLEVLAGDFSDADLGLRKADWDRLADEVDLIVHSGALVNHVLPYSQLFGPNVVGTAEVAKLALTKRLKPVTYLSTVAVAVGVEPSAFEEDGDIRDVSAVRSIDEGYANGYGNSKWAGEVLLREAYEHAGLPVRVFRSDMILAHRKYTGQLNVPDQFTRLILSLLATGIAPKSFYQLDATGGRQRAHYDGIPVDFTAEAITTLGLAGSDGYHSFDVFNPHHDGVGLDEFVDWLVEAGHPISRVDDYAEWLSRFETSLRGLPEAQRQHSVLPLLHAFAQPAPAIDGSPFQTKNFQSSVQEAKVGAEHDIPHLDKALIVKYAEDIKQLGLL
What is the function of this protein?
Catalyzes the ATP- and NADPH-dependent reduction of carboxylic acids to the corresponding aldehydes (PubMed:28719588).  Catalyzes the reduction of a very wide range of carboxylic acids, including benzoic acids, heterocyclic, phenylacetic, phenylpropanoic and fatty acid substrates (PubMed:28719588).
What are the official names of this protein?
Carboxylic acid reductase, CAR, ATP/NADPH-dependent carboxylic acid reductase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. Carboxylic acid reductase subfamily.
Protein: CX6B1_HUMAN
Sequence: MAEDMETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRVYQSLCPTSWVTDWDEQRAEGTFPGKI
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6B1, Cytochrome c oxidase subunit VIb isoform 1, COX VIb-1.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 6B family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: SPXH_BACSU
Sequence: MTNYQHELYFAHCHGHPKKPLEIYMFVDPLCPECWSLEPVIKKLKIRYGRFFTLRIIASASLTALNKKRKKHLLAEAWEKIASRSGMSCDGNVWFEQDQPLSSPYMAALAFKAAELQGRKAGMQFLRNMQESLFVSKKNITDENVLLEIAENTSLDLEEFKKDLHSQSAVKALQCDMKIAAEMDVSVNPTLTFFNTQHEDEGLKVPGSYSYDVYEEILFEMLGDEPKPSETPPLECFIEYFRFVASKEIALVYDLSLEEVEKEMKKLAFAKKVAKVEAKHGMFWKSLSTYSDEYQSCEK
What is the function of this protein?
Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions (PubMed:17908206, PubMed:19074380, PubMed:24942655).  Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP (PubMed:24942655, PubMed:27191337).  Is specific for Spx and does not enhance proteolysis by ClpCP protease (PubMed:19074380).  Probably binds 2 zinc ions (PubMed:19074380).
What are the official names of this protein?
ClpXP adapter protein SpxH.
What is the protein family that this protein belongs to?
Belongs to the SpxH family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Soluble under non-stress conditions and aggregates in response to stress conditions such as disulfide stress, heat and ethanol.
Protein: RL5_METM6
Sequence: MSFQEVWEKEPMKKPRIQKVTVNFGVGEAGDRLTIGAKVIEELTGQSPVRTLAKQTNPAFGIRKKLPIGLKVTLRGKNAEEFLGNAFTAFKTSGKVLYASSFDQVGNFSFGVPEHIDFPGQKYDPSIGIYGMDVCVTFEKSGYRVKSRKVKRSHIPKKHLVTKDEAIEYIQTKFDTEVVRE
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PPO_VICFA
Sequence: MTSISALSFISTINVSSNSKISHSSVYPFLQKQHQSSKLRKPKRQVTCSSNNNQNNPKEEQELSNIVGHRRNVLIGLGGIYGTLATNPSALASPISPPDLSKCVPPSDLPSGTTPPNINCCPPYSTKITDFKFPSNQPLRVRQAAHLVDNEFLEKYKKATELMKALPSNDPRNFTQQANIHCAYCDGAYSQIGFPDLKLQVHGSWLFFPFHRWYLYFYERILGSLINDPTFALPFWNYDAPDGMQLPTIYADKASPLYDELRNASHQPPTLIDLNFCDIGSDIDRNELIKTNLSIMYRQVYSNGKTSRLFLGNPYRAGDAEPQGAGSIENVPHAPVHTWTGDNTQTNIEDMGIFYSAARDPIFYSHHSNVDRLWYIWKTLGGKKHDFTDKDWLESGFLFYDENKNLVRVNVKDSLDIDKLGYAYQDVPIPWEKAKPVPRRTKVQKLVEVEVNDGNLRKSPTIFLVRQQSPRKYVTFPLVLNNKVSAIVKRPKKLRSKKEKEEEEEVLVIEGIEFYMNIAIKFDVYINDEDDKVGAGNTEFAGSFVNIPHSAHGHKNKKIITSLRLGITDLLEDLHVEGDDNIVVTLVPKCGSGQVKINNVEIVFED
What is the function of this protein?
Catalyzes the oxidation of mono- and o-diphenols to o-diquinones.
What are the official names of this protein?
Polyphenol oxidase A1, chloroplastic, PPO, Catechol oxidase.
What is the protein family that this protein belongs to?
Belongs to the tyrosinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid lumen.
Protein: YFIZ_BACSU
Sequence: MICKKASSKWIVLVCLIFILLTAVCASVVYGYTGTSWRQVYQAFTSFNGTNEHVIIKDVRLPRALVATVVGASLAAAGALMQALTKNPLASPGIFGINAGAGFFIVAGSFFLHIQSPQALVWSSFLGAAFTAAIVYAAGSLGREGLTPIKLTLAGAAMAAMFSSLTQGLLSVNELELAQVLFWLTGSVQGRSLDLLMTMFPYAAAALVICFFLGQKINLLVMGEDVAKGLGQKTGLLKFVMALCVVMLAGSAVAIAGPISFIGIIIPHFARFVVGNDYRWVLPFSAVLGAILLVCADIGARYIIMPQEVPVGVMTAIIGMPVFVYIARRGAKL
What is the function of this protein?
Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen.
What are the official names of this protein?
Probable siderophore transport system permease protein YfiZ.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL5_CLOK1
Sequence: MSLRLQEKYEKEVVPALMDKFGYKNIMQAPKLEKIVINMGVGEAKDNPKVLESAVNDLTIITGQKPVLTRAKKSIANFKLRENMAIGCKVTLRKQYMYEFADKLMNVALPRVRDFSGVSDKSFDGRGNYSLGIKEQLIFPEIEYDKIDKVRGMDIVFVTTANTDEEAKELLRLFGMPFAQK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RK23B_SORBI
Sequence: MDGIKYAVFTEKSLRLLGKNQYTFNVESGFTKTEIKHWVELFFGVKVVAVNSHRLPGKGRRMGPILGHTMHYRRMIITLQPGYSIPLLDRETN
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23-B, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: GLCM4_CAEEL
Sequence: MILNISVSLLIFLAFYGFSSDAKSLPCSEVKKEYGIVCRCNATYCDTIEPLGTVTSGKAVVYTTSRNGKRMNRSELKHTTSSTAKTKVYVNTTQSFQPVMGFGAAFTDAAGINMKMLPQTMQDQIIQQYFSDDGLGYVFGRVPMASTDFSTHEYSYDDVKFDFDLKNFNLTVEDLQYKIPFIKKAMTASGGKLKLFATPWSSPGWMKTSGRMVGAGELLGDQNGKYYQTWAQYFVKFFEAYHAQGIDFWSLTPQNEPTTGIDPLWKWQTLFFDASMERNFIKKLLGPALASSPVTKNLKIMINDDQRINLPHWPNVILTDPTAAQYVHGIAIHWYEDFIDPATVLTETHEKFPDYFLLATEACAGYFPADGPKLGSWSRAEQYANDLIKDMGNWVGGWVDWNYILDLQGGPNLAKNFVDSTIIVNATAQEYYKQPIWHVMAQFSKFVKPGAIRVGINIIEKSVDVEGLSFLNQDGTKTVVLLNKNEVLSFDVAISDVSAPNVIYDLTIQPNSLITIVYK
What are the official names of this protein?
Putative glucosylceramidase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 30 family.
Protein: NDK_HELP2
Sequence: MKQRTLSIIKPDALKKKVVGKIIDRFESNGLEVVAMKRLHLSVKDAENFYAIHRERPFFKDLIEFMVSGPVVVMVLEGEDAVAKNRDLMGATDPKLAQKGTIRADFAESIDANAVHGSDSLENAHNEIAFFFATRDL
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPMT_XANC5
Sequence: MDTNFWLERWQLGHTGFHQQEVLPLLQKHWHALDLPKEARVLVPLCGKTLDMHWLAAQGHRVLGVELSPLAVTQFFDEAGLQPQRHSSAAGEHFIAGPIEIICGDAFALDASALADCTAVYDRAALVALPAELRQHYLQTVYAPLPTHCHGLLITLEYPQAEKAGPPFSVDATHVHALFDSAWQVDQLEHRDILDQEPRFRDEGVTGLSTAVYRLQGR
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XPO5_MOUSE
Sequence: MEMEQVNALCEELVKAVTVMMDPSSTQRYRLEALKFCEEFKEKCPICVPCGLKLAEKTQIAIVRHFGLQILEHVVKFRWNSMSRLEKVYLKNSVMELIANGTLRILEEENHIKDVLSRIVVEMIKREWPQHWPDMLMELDTLFRQGETQRELVMFILLRLAEDVVTFQTLPTQRRRDIQQTLTQNMERILNFLLNTLQENVNKYQQMKTDSSQEAEAQANCRVSVAALNTLAGYIDWVSLNHITAENCKLVETLCLLLNEQELQLGAAECLLIAVSRKGKLEDRKRLMILFGDVAMHYILSAAQTADGGGLVEKHYLFLKRLCQVLCALGNLLCALLALDANIQTPINFGMYLESFLAFTTHPSQFLRSSTHMTWGALFRHEVLSRDPALLAVIPKYLRASMTNLVKMGFPSKTDSPSCEYSRFDFDSDEDFNAFFNSSRAQHGEVVRCVCRLDPKTSFQMAAEWLKYQLSASIDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEAMTFFLESVINQMFRTLDKEELPVSDGIELLQLVLNFEIKDPLVLSCVLTNVSALFPFVTYKPAFLPQVFSKLFSFVTFESVGESKAPRTRAVRNVRRHACSSINKMCRDYPDLVLPNFDMLYSHVKQLLSNELLLTQMEKCALMEALVLVSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRALSDIDSFIAYVGADLKSCDPAVEDPCGLNRARMSFCVYSILGVMRRTSWPSDLEEAKAGGFVVGYTPSGNPIFRNPCTEQILRLLDNLLALVRTHNTLYTPEMLTKMAEPFTKALDIVESEKTAILGLPQPLLEFNDHPVYRTTLERMQRFFGILYENCYHILGKAGPSMQQDFYTVEDLASQLLGSAFVNLNNIPDFRLRSMLRVFVKPLVLFCPSEHYETLISPILGPLFTYLHMRLSQKWHVINQRSILCGEDEIAEDNPESQEMLEEQLVRMLTREAMDLIMACCVSKKTADHTAAPTADGDDEEMMATEVAPSSVVELTDLGKCLMKHEDVCTALLITAFNSLTWKDTLSCQRATTQLCWPLLKQVMSGTLLADAVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEINKESLDQFDCKLLNPSLQKAADKRRKDHFKRLIAGCIGKPLGEQFRKEVHIKNLPWLFKKPKPMLETEVLDSEEGGLATIFEP
What is the function of this protein?
Mediates the nuclear export of micro-RNA precursors, which form short hairpins.  Also mediates the nuclear export of synthetic short hairpin RNAs used for RNA interference.  In some circumstances can also mediate the nuclear export of deacylated and aminoacylated tRNAs.  Specifically recognizes dsRNAs that lack a 5'-overhang in a sequence-independent manner, have only a short 3'-overhang, and that have a double-stranded length of at least 15 base-pairs.  Binding is dependent on Ran-GTP (By similarity).
What are the official names of this protein?
Exportin-5, Exp5, Ran-binding protein 21.
What is the protein family that this protein belongs to?
Belongs to the exportin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm.
Protein: SNW1_BOVIN
Sequence: MALTSFLPAPTQLSQDQLEAEEKARSQRSRQTSLVSSRREPPPYGYRKGWIPRLLEDFGDGGAFPEIHVAQYPLDMGRKKKMSNALAIQVDAEGKIKYDAIARQGQSKDKVIYSKYTDLVPKEVMNADDPDLQRPDEEAIKEITEKTRVALEKSVSQKVAAAMPVRAADKLAPAQYIRYTPSQQGVAFNSGAKQRVIRMVEMQKDPMEPPRFKINKKIPRGPPSPPAPVMHSPSRKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIADRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDEIRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNPRTSNEVQYDQRLFNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQNIYRPSKNLDKDMYGDDLEARIKTNRFVPDKEFSGSDRRQRGREGPVQFEEDPFGLDKFLEEAKQHGGSKRPSDSSRPKEHEHEGKKRRKE
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity).  Required in the specific splicing of CDKN1A pre-mRNA; the function probably involves the recruitment of U2AF2 to the mRNA.  May recruit PPIL1 to the spliceosome.  May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.  Involved in transcriptional regulation.  Modulates TGF-beta-mediated transcription via association with SMAD proteins, MYOD1-mediated transcription via association with PABPN1, RB1-mediated transcriptional repression, and retinoid-X receptor (RXR)- and vitamin D receptor (VDR)-dependent gene transcription in a cell line-specific manner probably involving coactivators NCOA1 and GRIP1.  Is involved in NOTCH1-mediated transcriptional activation.  Binds to multimerized forms of Notch intracellular domain (NICD) and is proposed to recruit transcriptional coactivators such as MAML1 to form an intermediate preactivation complex which associates with DNA-bound CBF-1/RBPJ to form a transcriptional activation complex by releasing SNW1 and redundant NOTCH1 NICD.
What are the official names of this protein?
SNW domain-containing protein 1, Nuclear protein SkiP, Ski-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the SNW family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL3_CLOPE
Sequence: MKKAIIGKKVGMTQIFDENGRVIPVTVVEAGPCVVVQKKTVETDGYDAIQVGFGELREKLVNKPRKGHFAKAGVSLRRTLKEFRMEDVANYNVGDEIKVDTFEIGDKVDVSGVSKGKGFQGTIKRWNASRGPMSHGSKFHRAPGSMGAASDPSRTFKNKRMPGHMGAKNTTVLNLEVVKIMPEKNIILIKGGIPGPNKGTVVIRNSVKA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: NU1M_SMICR
Sequence: MFILNLLLYIIPILLAVAFLTLIERKVLGYMQFRKGPNIVGPYGLLQPFADAVKLFTKEPLRPLTSSILMFILAPILALSIALTIWTPLPMPNSLLDLNLGLLFILSLSGLSVYSILWSGWASNSKYALIGALRAVAQTISYEVSLAIILLSVMLINGSFTLKTLSTTQENWWLIITTWPLAMMWYISTLAETNRAPFDLTEGESELVSGFNVDYAAGPFAMFFLAEYANIIAMNAITTILFMGSSLTLNLTHIDSITFMMKTLLLTMAFLWVRASYPRFRYDQLMHLLWKNFLPLTLALCLWYISLPIALSCIPPQL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 1, NADH dehydrogenase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YIM5_BPPH1
Sequence: MIDKIKKGYSLRELADYLDESDAIPKRGYKWHIASILVILKNPVLYGGFRWAGEILEGAFEGYISKKEFEQLQKMLHDRQNFKRRETSSIFIFQAKILCPNCGSRLTCERSIYFRKKDNKNVESNHYRCQHAP
What are the official names of this protein?
Uncharacterized immunity region protein 5.
Protein: TAP25_BPMD2
Sequence: MTNVFTIDAFREEVKKKYEPVTIGISEDVTVELKPLLKLGQKAREAVVEAVKEVEDIPDIDEDDEEAEELVDEYSLRICEIVAKVFRLIATKPKKLIAALDEEEDPRIRAELYATVLRTWMVETQLGESRALAELIDKFGGAILSDLSEYHGVDLRDLFRDEDPLSPRYVLNLVIHLPKTGAFYAERRGGQQYRGWDEDRYALADIYDAVQAGNHILLMANRDPKKPKPKAPKAYPRPDDFEKTTPKPGSFAAMVVAAKKAAREKREREEANAE
What is the function of this protein?
Promotes tail assembly by creating a scaffold for the tail tube proteins.  The tail assembly proteins Gp24 and Gp25 would wrap the linear tape measure protein to create a tail assembly scaffold.  It would allow polymerization of tail tube protein during which Gp24 and Gp25 are released and therefore are absent from the mature virion.  The tail assembly protein Gp25 is produced by a rare -1 ribosomal frameshift.  The ratio Gp24/Gp25 is important for proper tail assembly.
What are the official names of this protein?
Tail assembly protein Gp25, Gene 25 protein, Gp25.
What is the protein family that this protein belongs to?
Belongs to the L5likevirus tail assembly protein family.
Protein: FABA_RHIME
Sequence: MNTRQSSFSYEEILICGRGEMFGPGNAQLPLPPMLMFNRITDISETGGPNDKGYVRAEFDITPDLWFFPCHFMGDPVMPGCLGLDAMWQLTGFFLGWLGEAGKGRAISTGEVKFTGMVTPKTKLVEYGIDFKRVMRGRLVLGIADGWMKADGETIYKATDLRVGLFQEKAD
What is the function of this protein?
Necessary for the introduction of cis unsaturation into fatty acids.  Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP.  Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
What are the official names of this protein?
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA, Beta-hydroxydecanoyl thioester dehydrase, Trans-2-decenoyl-[acyl-carrier-protein] isomerase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MENG_BACLD
Sequence: MVQSKEQRVHGVFEKIYKNYDQMNSVISFKQHKKWRDKTMQLMNVPKGATALDVCCGTGDWTIALADAAGETGEIKGLDFSKNMLSIAEQKTESYSQIELIHGNAMELPFPDNTFDYVTIGFGLRNVPDYLTVLKEMARVVKPGGQVVCLETSQPEMFGFKQLYFLYFRFIMPMFGKLFAKSFKEYSWLQESAREFPGMKELAALFEEAGLKNVQYHPFTGGVAATHVGWKR
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).
What are the official names of this protein?
Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: C3H52_ARATH
Sequence: MDARKRGRPEAAASHNSNGGFKRSKQEMESISTGLGSKSKPCTKFFSTSGCPFGDNCHFLHYVPGGYNAAAQMTNLRPPVSQVSRNMQGSGGPGGRFSGRGDPGSGPVSIFGASTSKISVDASLAGAIIGKGGIHSKQICRETGAKLSIKDHERDPNLKIIELEGTFEQINVASGMVRELIGRLGSVKKPQGIGGPEGKPHPGSNYKTKICDRYSKGNCTYGDRCHFAHGESELRRSGIA
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 52, AtC3H52.
Protein: BUK_BACHK
Sequence: MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMVKKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG
What are the official names of this protein?
Probable butyrate kinase, BK, Branched-chain carboxylic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLO2_ACAM1
Sequence: MQIHRLPAFSDNYIFVLHDPGQNIAAVVDPADPQPVLKKLAELGAELVAIFNTHHHSDHVGGNRTLLQAFPNTVVYGGEQDRGRIPGQQHFLKEGDQVSFAHRRAEVYFVPGHTRAHIAYYFPPTTGEEWGELFCGDTLFAGGCGRLFEGTPAQMVDSLSKLRNLPETTRVWCAHEYTLKNLQFALTVDSDNSHLKNRFKQVQNARNLSQPTVPSDIGLEKQTNPFLRWDQPHLIIHTKSNTPVQCFARLRGMKDQF
What is the function of this protein?
Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
What are the official names of this protein?
Hydroxyacylglutathione hydrolase, Glyoxalase II, Glx II.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
Protein: Y1028_HAEIN
Sequence: MKLFNFKKLSMLIAGFTLVTSPALAEISLRFGYEAPRSDSQHSAAKKFNDLLMKKTKGEIKLKLFPDSTLGNAQTMISSVRGGTIDLEMSGSPNFTGLEPKLNVIDIPFIFKDREHVYKVLDGEVGQNLLKDLEKQGLKGLAFWDVGFRAFSNSKQTVTKPEHIKGLKVRTNQNPMYIEAFKLLGSNPVPMPLAELYTALETRAVDAQEHPIGIFWSSKLYEVQKYLSLTNHGYTPLIVVMNKAKFDSLLPALQTAIIEAAKEAGQFQRDLNVKNEQNIISKLRKQGVEVIEKINTEPFKTLIEEKVRKSFIEKHGDDLLKKVDALSE
What are the official names of this protein?
Uncharacterized protein HI_1028.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 7 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: FMT_HAEIN
Sequence: MKSLNIIFAGTPDFAAQHLQAILNSQHNVIAVYTQPDKPAGRGKKLQASPVKQLAEQNNIPVYQPKSLRKEEAQSELKALNADVMVVVAYGLILPKAVLDAPRLGCLNVHGSILPRWRGAAPIQRSIWAGDVQTGVTIMQMDEGLDTGDMLHKVYCDILPTETSTSLYNKLAELAPSALIDVLDNLENGKFIAEKQDGSQSNYAEKLSKEEAQLNWSLSAMQLERNIRAFNPWPIAYFSTEDKDGNAHTLKVYQAKVLPHQDKPAGTILSADKNGIQIATVDGVLNLLQLQSAGKKPMSAQDLLNGRAEWFTIGKVLA
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: AACUS_ASPA1
Sequence: MLNLAQLQSQTRELLAALKQLTEHCPSAVDGTTEGMIPGLSPWSTTGESGEATRARETVLKCLAKLQVSLAGPIDVLQHMASQTQLLACLQWLGEFQVPACIPLDGSASIKDVAELIGVPENHICRIVRMAITAGFLQEPELGHVAHSPLSAAFVTNPSYLDAAMFLARITTPAALNMPSITRQRTAGMCERVNQVEQNNNIINMVTSSTLDETALPRLERQWYAYLRFGTGNLCDTATDIISCLNSFQGTSATVVEVGARSLDRAMTLANRYPTLRFIIQIHLPSSASGSGKDEAKYDRTRAIRSHSQITVQYRTPGTPQQIQDAAVYIINFPLPFPGVSSCSISAQLETELRAHLQALRLSPAATLVLTAPALPERGARGTEVAVLTRIRDLSFLQLANDREPEISELINLLNGVGDSEGRFVVVKK
What is the function of this protein?
Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of the tetrahydroxanthone dimer secalonic acid D.
What are the official names of this protein?
Transcriptional coactivator AacuS, Secalonic acid biosynthesis cluster protein S.
What are the subcellular locations of this protein?
Nucleus.
Protein: TM196_PONAB
Sequence: MCTSGQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLALREHKPQLGDSSPFLLCGICGILCAKKKSGLVMILFSACCICGLIGGILNFQFLRAVTKKTSSLYPLHLASMSLACIGIGGCTLSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKRLRAIEITDLPSCPVVPPTPELPTRK
What are the official names of this protein?
Transmembrane protein 196.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.