PharMolix/UniProtQA huggingface dataset:
Protein: 3XYN2_VIBSX
Sequence: MKKLAKMISVATLGACAFQAHALDGKLVPDQGILVSVGQDVDSVNDYSSAMGTTPAGVTNYVGIVNLDGLSTDADAGAGRNNIVELANQYPTSALIVGVSMNGEVQNVANGQYNANIDTLIRTLGEFDRPVYLRWAYEVDGPWNGHNTEDLKQSFRHVYQRIRELGYADNISMVWQVASYCPTAPGQLGTWWPGDDVVDWVGLSYFAPQDCNWDRVNEAAQWARSHNKPLFINESSPQRYQLADLTYSTDPAKGTNRQAKTDQQIWSEWFEPFFQFMVDNQDILKGFTYINADWDSQWRWAAPYNEGYWGDSRVQVIPYIKQKWQETLSDPKFIRHSDELFAQLGYGNSDGGNGGDNGGDNGGDNGGETPENCTDDFNFNYVSDNEIEVYHVDKGWSAGWNYLCLDDYCLSGTKSNGAFSRSFSAQLGQTYKMTFKVEDITGQGQQIIDKTVTFTNQVCN
What is the function of this protein?
Catalyzes the hydrolysis of beta-1,3-xylan into oligosaccharides, mainly xylotriose and xylobiose with smaller amounts of xylotetraose, xylose, xylopentaose and xylohexaose.  Weakly active toward beta-1,3-xylotriose, yielding xylose and xylobiose.  Converts beta-1,3-xylotetraose into xylotriose, xylobiose and xylose.  Converts beta-1,3-xylopentaose into xylotetraose, xylotriose, xylobiose and xylose.  Does not hydrolyze xylobiose, p-nitrophenyl-beta-xyloside, beta-1,4-xylan, curdlan or carboxymethylcellulose.
What are the official names of this protein?
Beta-1,3-xylanase TXYA, Endo-1,3-beta-xylanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 26 family.
Protein: CHKA_HUMAN
Sequence: MKTKFCTGGEAEPSPLGLLLSCGSGSAAPAPGVGQQRDAASDLESKQLGGQQPPLALPPPPPLPLPLPLPQPPPPQPPADEQPEPRTRRRAYLWCKEFLPGAWRGLREDEFHISVIRGGLSNMLFQCSLPDTTATLGDEPRKVLLRLYGAILQMRSCNKEGSEQAQKENEFQGAEAMVLESVMFAILAERSLGPKLYGIFPQGRLEQFIPSRRLDTEELSLPDISAEIAEKMATFHGMKMPFNKEPKWLFGTMEKYLKEVLRIKFTEESRIKKLHKLLSYNLPLELENLRSLLESTPSPVVFCHNDCQEGNILLLEGRENSEKQKLMLIDFEYSSYNYRGFDIGNHFCEWMYDYSYEKYPFFRANIRKYPTKKQQLHFISSYLPAFQNDFENLSTEEKSIIKEEMLLEVNRFALASHFLWGLWSIVQAKISSIEFGYMDYAQARFDAYFHQKRKLGV
What is the function of this protein?
This isoform plays a key role in lipolysis of lipid droplets following glucose deprivation (PubMed:34077757).  In response to glucose deprivation, phosphorylated by AMPK, promoting localization to lipid droplets (PubMed:34077757).  Phosphorylation is followed by acetylation by KAT5, leading to dissociation of the homodimer into a monomer (PubMed:34077757).  Monomeric CHKA isoform 1 is converted into a tyrosine-protein kinase, which phosphorylates lipid droplet structural proteins PLIN2 and PLIN3, leading to lipolysis of lipid droplets (PubMed:34077757).
What are the official names of this protein?
Choline kinase alpha, CK, CHETK-alpha, Ethanolamine kinase, EK.
What is the protein family that this protein belongs to?
Belongs to the choline/ethanolamine kinase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. SUBCELLULAR LOCATION: [Isoform 1]: Lipid droplet. Note=Isoform 1 localizes to lipid droplets following phosphorylation by AMPK.
Protein: MPTA1_METAR
Sequence: MKFVQLPDVQASNPDVMVGLTRVGVTEVKKMVEITRSDKRPIILIPTFDIFVDLPSYRKGANLSRNLEAIDRTLEEALNQPVYRIEDLCVDVAKRLLETHEYASNAEVRMHGEYMMKKKSPKTGLECQEVYDIYADAIVVRGGIIRKTIGAKVIAMTACPCAQEISKETAFKKLAALGVADNVIAEFLDDMPMPTHNQRGVGTIKIESGNDVKVSIEAIIDIIENSMSSQMYELLKREDERYVVHSAHKNPKFVEDCVRTMAKNLVRKFPSLPDDAVITIEQVNEESIHRHNAFAERMATFGELKKEMLSNGPVL
What is the function of this protein?
Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
What are the official names of this protein?
GTP cyclohydrolase MptA 1, GTP cyclohydrolase IV 1.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase IV family.
Protein: RL25_FRACC
Sequence: MSAAMSEVRIAAEPRTEFGKGGARRTRRAGKVPAVLYGHGKPPRHIALPAHDLLHAFKTDAGTNVLLTLELAEGTELALAKDVQRHPIKGSFEHIDLVLVARGEKVVADIPVQVIGEPHPDTLVDQQVTTIAVKADATRLPGPIEVDITGLEPGTSILARQLVLPAGSELDADPDLVVVQCLAKRTNAQQEASLGETPVAEEAGVASASV
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: K1B24_MOUSE
Sequence: MWFLILFLALSLGGIDAAPPVQSRVVGGFKCEKNSQPWHVAVFRYNKYICGGVLLNPNWVLTAAHCYGNATSQYNVWLGKNKLFQREPSAQHRWVSKSFPHPDYNMSLLNDDIPQPKDKSNDLMLLRLSEPADITDAVKPIDLPTEEPKLGSTCLASGWGSITPTKWQKPNDLQCVFIKLLPNENCTKPYLHKVTDVMLCAGEMGGGKDTCAGDSGGPLICDGILHGITSWGPVPCGKPNAPAIYTKLIKFASWIKDTMAKNP
What is the function of this protein?
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
What are the official names of this protein?
Kallikrein 1-related peptidase b24, Glandular kallikrein K24, mGK-24, Tissue kallikrein 24.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein: RL10_ALISL
Sequence: MALNLQDKKAIVAEVNEAASGALSAVVADSRGVTVGAMTSLRKQAREAGVYMRVVRNTLARRAVEGTQYECLQDTFTGPSLLAFSNEHPGAAARLFKDFAKENKNFEIKAAAFEGAVTDADVLATLPTYDEAIARLMMCMKEASAGKLVRTIAAVRDQKEEAEA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: COLL4_MIMIV
Sequence: MANNVNLLYGLPQRVITLPANLIQSKSKIFIGNGDPNCIIGNNCDMYIDKNSNRIFYKCGCNWLLTGTIMGDNGFIGLRGSKGDTGNKGEIGDNGENGDIGQIGDNGSIGSKGIKGMNGFNGSKGIKGDKGTDGIKGDKGQDNFGSKGQKGETGSKGDDGIKGITGSKGFKGDPGTKGENGINGTKGLKGSQGDLGTKGDDGIKGIIGSKGIKGDPGNKGEDGIKGTNGLKGSKGETGSKGDDGTKGITGLKGTKGNSGSKGDDGDKGIQGLKGEFGTKGNVGDKGDTGINGEKGSDGDKGNKGLDGIKGDLGDDGIKGDKGIKGLKGDTGNSDKGDKGSKGDSNFSKGGIGDKGSKGDNGSKGESGDKGIFGLKGSKGDIGDKGEKGDLGDTGLKGSKGLKGSKGDKGLVNVKGENGFVGDLGSKGSKGDKGESGDKGDIGIKGDKGAKGVTGDKGDKGTKGFIGNVGFKGDTGDKGIIGDNGSKGIKGSSNNKGDKGDKGNTGDKGITNTKGIKGDKGIKGSKGDLGSVGEKGEKGTKGDIGTKGETGLKGIIGDKGELGSKGIKGLSESFIESFYQEIPGTFVSTVPDGAVFGYLSAAGGGGGGGGIELSSLAGGGGGGSGCFYLLPLTVYPGSQFTGTIGQGGSGSTISAVLATKGSDTVINYGTLTFIAHGGFPGSSTLELGGNGDTVTYPLPVTPAPGGTGGNMTNGSNGSTSIFMFSGAGGGASGLNSGFNGGNVGPYVGGTSSPQIAGGGGGASAFGNGGRGGNTTQAATKGEYGSGGGGGSEFSPSGSTNGGDGGDGFVRIDYFMVPR
What is the function of this protein?
May participate in the formation of a layer of cross-linked glycosylated fibrils at the viral surface thus giving it a hairy-like appearance.
What are the official names of this protein?
Collagen-like protein 4.
What are the subcellular locations of this protein?
Virion.
Protein: NKRF_MOUSE
Sequence: MEKILHMAEGIDIGEMPSYDLMLPKPSKGQKRYLSTYDGQNPPKKQAGSKFHVRARFEPVHFVASSSKAERQEDPYGPQTKDVNGRTHFASMPRNFYQDYTQDSFSIQDGNSQYCNSSGFIFTKDQPVATNMYFDSGNPAPSSTSQQANCQPAPEPPPSQMYPESLVAEKQYFIEKLTATIWKNLSNPEMTSGSDKINYTYMLTRCIQACKTNPEYIYAPLKEIPPADIPKNKKLLTDGYACEVRCQNIYLTTGYAGSKNGSRDRATELAVKLLQKRIEVRVVRRKFKHIIGEDLVVCQIGMLSYEFPPALKPPEDLVVLGKDASGQPIFNSSAKHWTNFVITENANDAIGILNNSASFNKMSIEYKYEMMPNRTWRCRVFLQDHCLAEGYGTKKTSKHAAADEALKVLQKTQPTYPSVKSSQCHSGSSPKGSGKKKDIKDLVVYENSSNPVCTLNDTAQFNRMTVEYVYERMTGLRWKCKVILESEVIAEAVGVKKSVKYEAAGEAVKTLKKTQPTVINNLKKGTVEDVISRNEIQGRSAEEAYKQQIKEDNIGNQLLRKMGWTGGGLGKSGEGIREPISVKEQHKREGLGLDVERVNKIAKRDIEQIIRNYARSESHSDLTFSTELTNDERKQIHQIAQKYGLKSKSHGVGHDRYLVVGRKRRKEDLLDQLKQEGQVGHYELVMPQAN
What is the function of this protein?
Enhances the ATPase activity of DHX15 by acting like a brace that tethers mobile sections of DHX15 together, stabilizing a functional conformation with high RNA affinity of DHX15.  Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity.  Also involved in the regulation of IL-8 transcription.  May also act as a DNA-binding transcription regulator: interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes.
What are the official names of this protein?
NF-kappa-B-repressing factor, NFkB-repressing factor, Transcription factor NRF.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL28_MYCCT
Sequence: MARRDALTGKSALSGQSRSHALNATKRKWNLNLQKVRVMDENGSVFNIKVSARTLRTLKKQEKIV
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: MED8_KLULA
Sequence: MTDTPSNTDPLQSAIAPDFSSVPTQALDALRMKFSQLTASLSKIRDEMSRAELPQWYTLQAQLTVTLSQLSSLTNTLDHYEETLDATVAYPLPSFPTTAHEGLITTLMRKKNIPEVDEWIKDAKETNGLDVDSLSDAEIKKLINKDKDITSWATKCLLDERAKHSYTGLYTTKERQTESIDDRDNLYTSSVSNVKTSRPFSVDKVLKFVNQGESY
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 8, Mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSB_MYCTA
Sequence: MTWPLPDRLSINSLSGTPAVDLSSFTDFLRRQAPELLPASISGGAPLAGGDAQLPHGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSGADTFGSDGGEK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PrcB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIS_BACSU
Sequence: MLQLNGKDVKWKKDTGTIQDLLASYQLENKIVIVERNKEIIGKERYHEVELCDRDVIEIVHFVGGG
What is the function of this protein?
Is the sulfur donor in the synthesis of the thiazole phosphate moiety of thiamine phosphate.
What are the official names of this protein?
Sulfur carrier protein ThiS, Thiamine biosynthesis protein ThiS.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein ThiS family.
Protein: PURA_YERPP
Sequence: MGKNVVVLGTQWGDEGKGKVVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVISIIGNGVVLAPDALMKEMTELEARGVPVRERLLLSEACPLILPYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVSDLFNKETFAIKLKEIVEYHNFQLVHYYKEAAVDYQKVLDDVLAIADILTAMVVDVSELLDNARKQGELIMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGIVKAYSTRVGAGPFPTELNDETGEFLRKQGNEYGATTGRSRRTGWLDIVAVRRAVQINSLSGFCMTKLDVLDGLKEVKLCVGYRMPDGREVDTTPLAAEGWEGIEPIYETMPGWSETTFGVKEHSKLPQAALNYIQRVEELTGVPIDIISTGPDRDETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NMDA1_DROPE
Sequence: MAGTDSPAAARFVYRCLLFAPAIVVGLLLPLTLPPIAAAQRHTASDNPSTYNIGGVLSNSESETYFHTIISHLNFDQQYVPRKVTYYDKTIRMDKNPIKTVFNVCDKLIENRVYAVVVSHEQTSGDLSPAAVSYTSGFYSIPVIGISSRDAAFSDKNIHVSFLRTVPPYYHQADVWLEMLSHFAYTKVIIIHSSDTDGRAILGRFQTTSQTYYDDVDVRATVELIVEFEPKLESFTEHLIDMKTAQSRVYLMYASTEDAQVIFRDAGEYNMTGEGHVWIVTEQALFANNTPDGVLGLQLEHAHSDKGHIRDSVYVLASAIKEMISNETIAEAPKDCGDSAVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREHQKKHVVGKFSYDSMRAKMRMNINDSEIIWPGKQNRKPEGIMIPTHLKVLTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNATDSTANEYCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYLLRNNSGAMTLRKEWTGLMGELVNERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHVVALVLYLLDRFSPFGRFKLSHSDSNEEKALNLSSAVWFAWGVLLNSGIGEGTPRSFSARVLGMVWAGFAMIIVASYTANLAAFLVLERPKTKLSGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANNYATAEQAIQDVKKGKLMAFIWDSSRLEYEASKDCELVTAGELFGRSGYGVGLQKGSPWTDSVTLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIIIEVIYKKHQVKKQKRLDIARHAADKWRGTIEKRKTIRASLAMQRQYNVGLNSTHPPGTISLAVDKRRYPRLGQRLGPERAWPGDAADVLRTRRPYELGKPGQSPKVMGATPAMLGRTRPQQNILPPRYSPGYTSDVSHLVV
What is the function of this protein?
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium.  Mediated by glycine.  This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning.  It mediates neuronal functions in glutamate neurotransmission.  Is involved in the cell surface targeting of NMDA receptors.  Plays a role in associative learning and in long-term memory consolidation (By similarity).
What are the official names of this protein?
Glutamate [NMDA] receptor subunit 1.
What is the protein family that this protein belongs to?
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density.
Protein: YOPR_BACSU
Sequence: MFNSEIKEKYLDTLSEGMVMQMRPIFAKAEITETLYNKDIYDFTSMQILELIRSFDQTTIGSVRRTLALLSLYIDWAISYKLSKGLTNLARTISEEELYECLGDKKLYITYSELEEMENQLVNYQSKAVLRLLFEGVSGLAHSELLSLTKKQVEDAMLNGNVLTLYDSKHGERKLKVSSECLVIALNAAQETKYKLKNGKAKGQTKEVFLVENDYVVKTKRTSNKGDGQASKFVITNLITDISEFFKINFLTPNTIVRSGHLYRAYQLYKEKGVIDNSVRYQIIDDFNLRVKSKYRAVYSMQDYINEEEVNKYYAEELGLKETTI
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YopR.
Protein: ALF1_STAAW
Sequence: MNKEQLEKMKNGKGFIAALDQSGGSTPKALKEYGVNEDQYSNEDEMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVEGKYTADYLADKGVVPFLKVDKGLAEEQNGVQLMKPIDNLDSLLDRANERHIFGTKMRSNILELNEQGIKDVVEQQFEVAKQIIAKGLVPIIEPEVNINAKDKAEIEKVLKAELKKGLDNLNADQLVMLKLTIPTEPNLYKELAEHPNVVRVVVLSGGYSREKANELLKDNAELIASFSRALASDLRAGQSKEEFDKALGDAVESIYDASVNKN
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: H1B_OLILU
Sequence: TYYELIKAAILALKERNGSSAQAIKKYILENNKIEFQQTFLR
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.
What are the official names of this protein?
Histone H1B.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PURT_SALPK
Sequence: MTLLGTALRPAATRVMLLGAGELGKEVAIECQRLGIEVIAVDRYPDAPAMHVAHRSHVINMLDGEALRHVITEEKPHYIVPEIEAIATDTLRELEGEGLNVVPCARATQLTMNREGIRRLAAEELGLPTSTYRFADSEASFHDAVAAVGFPCIVKPVMSSSGKGQSFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQQDGDYRESWQPQQMSELALKRAQEIARHVVLALGGHGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGMPIGAIRQYGPAASAVILPQLTSQNVTFDDVHAAVGAGVQVRLFGKPEIDGTRRLGVALATGENVEEAVIRAKKAASRVTVKG
What is the function of this protein?
Involved in the de novo purine biosynthesis.  Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR).  Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.
What are the official names of this protein?
Formate-dependent phosphoribosylglycinamide formyltransferase, 5'-phosphoribosylglycinamide transformylase 2, Formate-dependent GAR transformylase, GAR transformylase 2, GART 2, Non-folate glycinamide ribonucleotide transformylase, Phosphoribosylglycinamide formyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the PurK/PurT family.
Protein: TERS_BPP21
Sequence: MKVNKKRLAEIFNVDPRTIERWQSQGLPCASKGSKGIESVFDTAMAIQWYAQRETDIENEKLRKELDDLRAAAESDLQPGTIDYERYRLTKAQADAQELKNAREDGVVLETELFTFILQRVAQEISGILVRVPLTLQRKYPDISPSHLDVVKTEIAKASNVAAKAGENVGGWIDDFRRAEGS
What is the function of this protein?
Component of the terminase that processes and encapsidates viral genomes during virion assembly.  The terminase is composed of two small and one large subunits.  To initiate packaging, it binds a specific sequence, at the junction of adjacent viral genomes in the concatemeric DNA substrate.  Next, in a reaction stimulated by the presence of proheads and ATP but not requiring ATP hydrolysis, the terminase creates two nicks at a specific site, one on each stand.  Terminase then separates the cohesive ends in a reaction requiring ATP hydrolysis.  The heterotrimer remains bound to the left end of the genome to be packaged, forming a stable DNA-protein complex known as complex I.  In a reaction facilitated by a viral assembly catalyst, gpFI, complex I binds a prohead, a preformed head shell precursor, to form complex II.  In another packaging reaction requiring ATP hydrolysis, the DNA is translocated into the prohead until the next specific site on the concatemer reaches the packaging complex.  At this time the downstream specific site is cut and the heterotrimer undocks from the DNA-filled head to remain bound to the left end of concatemer's next genome.  The new heterotrimer-DNA complex I binds another prohead to continue the processive, polarized packaging of viral genomes.  The terminase is dependent upon host integration host factor (ihfA/ihfB) for these activities.
What are the official names of this protein?
Terminase, small subunit, Gp1.
What is the protein family that this protein belongs to?
Belongs to the terminase small subunit family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: RS8_SPIKU
Sequence: MMIDTIADMLTRIRNANQRLHKSVKMPSSKMKVRIAEILKKEGYVEDFKVSGDIKKDLTLTLKYKGKTKVISGLKRISKPGLRVYVTVEEVPQVLNGMGIAIISTNQGIMTDKAAKKAHLGGEVIAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: PLIGA_NOTAT
Sequence: MKSLQIICLLFVLVARGSCHSCEICHNFGKDCQSDETEECASAEDQCGTVLMEVSSAPISFRSIHRKCFSSSLCKLERFDINIGHDSYLRGRIHCCDEARCEAQQFPGLPLSFPNGYHCPGILGVFSVDSSEHEAICRGTETKCINLAGFRKERYPIDIAYNIKGCTSSCPELRLNRTHEEHGNGLIKVECTEASKITPSE
What is the function of this protein?
Inhibits the enzymatic activity of all phospholipase A2 tested, binding them with micromole to nanomole affinity.
What are the official names of this protein?
Phospholipase A2 inhibitor NAI, Notechis ater inhibitor, NAI, gamma-PLI.
What is the protein family that this protein belongs to?
Belongs to the CNF-like-inhibitor family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted in blood plasma.
Protein: TNAA_SHIB3
Sequence: MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDREDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFDTGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIKGLTFTYEPKVLRHFTAKLKEV
What are the official names of this protein?
Tryptophanase, L-tryptophan indole-lyase, TNase.
What is the protein family that this protein belongs to?
Belongs to the beta-eliminating lyase family.
Protein: HXAAB_TAKRU
Sequence: MTCPNNQAGNSFFVDSLINVRPDSGSYYQSNGVYLPPGSEFSYGLSGGSCFPGIGKRNEPSAQSVISSPAPYVQGMETWLEASRPCRVDQPRGQHMAQCSFSPNIKEESTYCLYESDKCPKGATVDDISYSASSCPVTSTFPVPGYFRLSQTYASSRHYHDAHPNTDHFTLQQSARPDSRSSHRQAASAEPEQRANREESPVCAPCVPVREEDSRLSSEGSSSPEPAETPSLECPEKSGKGDGKNETAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMTRENRIRELSNSFSFS
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein Hox-A10b.
What is the protein family that this protein belongs to?
Belongs to the Abd-B homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PYG_NEOYE
Sequence: MSIPLLKYSLSTQNQRVDGYEVSPGEEQPRAYNTDNLPSAVEMDEVIWAAYRQIFSEHQILSSTSDSNLESQLRFNQIRIKDFIRGLILSESFRKLNYDVNNNYRFVEICVQRILGRDVYNEREKLAWSVVIASKGLESFVNMLLDSDEYEENFGDSIVPYQRRRIIAQRSKGEMPFNLKTPRYGADFKEKFGMPQFIWQGPVRQFRPQEQRPKAGDPALFLGMVNDLALFK
What is the function of this protein?
Linker polypeptides determine the state of aggregation and the location of the disk-shaped phycobiliprotein units within the phycobilisome and modulate their spectroscopic properties in order to mediate a directed and optimal energy transfer.
What are the official names of this protein?
Phycobilisome rod-core linker polypeptide cpcG.
What is the protein family that this protein belongs to?
Belongs to the phycobilisome linker protein family.
What are the subcellular locations of this protein?
Plastid, chloroplast. Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: FLIW_BDEBA
Sequence: MIISTSRFGQVELKQEDVLTFTEGLLGFADLRKFVLLDDPNDEIFAWLQSCEAPAIAFPVLEPELFAPQYKATLTKGDMEALKLTAQDKARYFSIVTIPDDPTLMTANLKAPVVVNIEARTARQCVLQDNNLAIREPIFTKLQQRVVQNPAVAIKNQSTGIDVATKLHVVRDAEL
What is the function of this protein?
Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin.  Binds to flagellin and participates in the assembly of the flagellum.
What are the official names of this protein?
Flagellar assembly factor FliW.
What is the protein family that this protein belongs to?
Belongs to the FliW family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROQ_ALIFM
Sequence: MENSEKLANSKEVIAYIAERFPKCFILEGEAKPLKIGIFQDLAERLSDDPKVSKTQLRAGLRQYTSSWRYLHGVKPGASRVDLDGNPCGELEEEHIEHAKATLEESKAKVATRRKEQAKKAREEAKAKKTARAATPPKRRPQPAAKKVEQPVETRALNADEITVGNNVSVNMGKGNMPATIVEINKDDVRIRLSNGLQMVVKAENLRS
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_PSE14
Sequence: MISDDTDQFNPRDAKSPEAAKGKSAKRREARQMATQALYQWHMAGHALNEIEAQFRVDNDFSNVDGAYFRELLHGVATNKTEIDTALSPCLDLTIEELDPVELAVLRLSTFELLKRIDVPYRVVINEGIELAKVYGSTDGHKFVNGVLDKLAPRLREVEVKAHKR
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: HDFR_SALA4
Sequence: MDTELLKTFLEVSRTRHFGRAAEALYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTTAGEKLLPYAETLMNTWQAARKEVAHTSRHNEFSIGASASLWECMLNAWLGRLYQLQEPQSGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQLLGHFTLALYCSSPARKKSELNYLRLEWGPDFQQHETGLIAADEVPVLTTSSAELARQQLSALNGCSWLPVNWANEKGGLHTVADSATLSRPLYAIWLQNSDKYSLICDLLKTDVLDEQ
What is the function of this protein?
Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon.
What are the official names of this protein?
HTH-type transcriptional regulator HdfR, H-NS-dependent flhDC regulator.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.