PharMolix/UniProtQA huggingface dataset:
Protein: UBP11_YEAST
Sequence: MLLNPDQILNLVRKVYEVDIKQFYSQLRLKNLRGLLDHAAHLFNVYLRDLEINQEMEALTAFIIGCYYLYLIIPQSLQFQTRNNLYSSYAKLKNDYQDEHVMGYVLKVVRDESTVIVDRYLAESNGICRTIKRKRAYSLPLRPLPVHMASLSIHNKFDGSLHEIPNELTKPTNDNSKEDIVRESNQIASSNKLEAGSEVAYYTSKEALSKPSYLKLSTGKDALFKTLSSPATAPPVHSLEVSSQIRDSSQDSSSSLSKVEKPKEEEGKIEAIESSAPKAYNLPVIEDSNDLLSELSITGLQNPCNTCYINSIIQCLFGTTLFRDLFLTKKYRLFLNTNKYPKEVQLSRSIYVLFKKMYLNGGRAIIPNRFLKMCKKLRPDLNIPDDQQDTQEFLLIVLARIHEELSNENVVKYYPDLVSYDANALQVNPSKYEKWYERNVITDGLSPIDHIYRGQLENILKCQRCGNSSYSYSTFYVLSLAIPKLSLYSFTSKSRKIKLEDCINLFTGDEELSGDNAWDCPNCRITDSKSKKEEITSQKKKSTIFGFHSRSRSKSPHHHHHHHHSSDDSTKNAKKRNSKKLTTIKSLDFIVLPPILVIHLSRFYYDLTKKNSTVITYPLILNIILKNGKVIRYKLYGTVNHSGNLINGHYTSVVNKEKSHEIGLNRQVWVTFDDDYIQQHRKDRNNFEAGKTEMSSDEVYVLFYERMDEENYEEEFC
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 11, Deubiquitinating enzyme 11, Ubiquitin thioesterase 11, Ubiquitin-specific-processing protease 11.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: DHYS_THEVO
Sequence: MDRKELLSKPVQDLRIDGNTTLSNLMAQFSNIGGFTAAKLYEAHSIISDMFLEDNTTFLSFPADIISTGLRGLINDVVKRKLVDVIITTSGTLDHDIARTFGKYYCGSFNYSDVELREININRLGNVLVPDESYGELIEEKVMEQLEKLYSIKKEWATVDLIKEIGLSINNESSILYNAAKNDIPIFVPGITDGSFGSQLWSFYEQHHDFKINLLEDEHRLSDIIFDAKKTGAIMVGGGISKHHTIWWNQFRDGLDYAVYITTAQEYDGSLSGAKLEEAISWKKVRPNARFVNIYGDATVIMPILMAPFL
What is the function of this protein?
Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
What are the official names of this protein?
Probable deoxyhypusine synthase, DHS.
What is the protein family that this protein belongs to?
Belongs to the deoxyhypusine synthase family.
Protein: NTPPB_COLP3
Sequence: MKTLVLGSTSPFRKTILEKLQLPFHCAKPNVDETEQKNESPQALVERLAIEKAKAVSSEYPNALIIGSDQVAVCEEEILGKPHNFDNAVVQLNKFSGKSITFYTGLCVYDSEKDKTIALVEPFIVHFNQLSQKDIANYLNAEQPYNCAGSFKSEGLGICLFSKLEGDDPNTLIGLPLIKLVGLLKQHGIDVLAEQSKLTV
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP).  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
7-methyl-GTP pyrophosphatase, m(7)GTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Maf family. YceF subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_ACIBS
Sequence: MALLIEDKKQIVAEVSEVASKAFAAVVADYQGLSVEQLTTLRVEARKLGVTTRIVRNTLAKRAFQGTQFDILNDNLVGPTILGFSTSEDDMGAAARLFEEFAKTNKAFELKAAAFDGKVYQGADVSVIANLPNQEKALTMLASVLQAPISKLGRLITALKEKNESEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: PURS_METTH
Sequence: MKFMVEVRIRLKKGMLNPEAATIERALALLGYEVEDTDTTDVITFTMDEDSLEAVEREVEDMCQRLLCNPVIHDYDVSINEMEG
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurS, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit III, FGAR amidotransferase III, FGAR-AT III, Phosphoribosylformylglycinamidine synthase subunit III.
What is the protein family that this protein belongs to?
Belongs to the PurS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIM_AGRRK
Sequence: MQNPTTTPGSLLTAMRANPPLVQCITNFVAMNIAANVMLAAGASPAMVHAEEEAGEFAAISGALTINIGTLSTGWLAGMTSAAQAANKAGKPWVLDPVAHYATSFRRRSVAQLLELQPTIIRGNASEIIALAGGTSRGQGVDSRDPVELAEEAAVQLAQKHRTIVAVTGATDFVTDGNKASRIEGGSPLMPQVTALGCSLTCLVGAFAATRPDHPLDATVAALAAFAVAGERAGRQVDGPGSFSWRFLDALAALDEKAIDSEARVISL
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase, 4-methyl-5-beta-hydroxyethylthiazole kinase, TH kinase, Thz kinase.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: MTEF4_MOUSE
Sequence: MASLGRQVPEWHRLLALSWACLVRQTPHLREQKQMSPSLSCKLTTVPGRGSFQEFSSITPQKYMQEPENRTRLVQCLHEEQKPCVDPESLEPEKVIRSLQDMGFAEAHIHSLFSIQPSVHPQQLLGIVSELLLLGLNPEPVFNALKKNPQLLKLSSMQMKRRSSYLRKLGLGEGKLKRVLSVCPEVFTMHQRDIDRVVKVLREKCLFTAQHITDVLHRCPTVLQEDPNELEYKFQYAYFRMGLTHLDIVRTNFLQYSITKIKQRHIYLERLGRYQTPDKKGQTQIPNPSLRNILRVSEAEFLARTACSSVEEFQVFKKLLDQEEEEESESHASEEEEEEEEEEELL
What is the function of this protein?
Regulator of mitochondrial ribosome biogenesis and translation.  Binds to mitochondrial ribosomal RNAs 16S, 12S and 7S (By similarity).  Targets NSUN4 RNA methyltransferase to the mitochondrial large ribosomal subunit.
What are the official names of this protein?
Transcription termination factor 4, mitochondrial, Mitochondrial transcription termination factor 4, mTERF domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the mTERF family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NUOI_ECOUT
Sequence: MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDGKDKGEAENEAKPIDVKSLLP
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y4437_DICDI
Sequence: MTINNSNIQTDLPNSENCDLKNETLNIYFNEPIPIIKHCTNKDTPTNINNNNNNNNNNNNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNNNNNNNINFSCNHILPQSALNSGICANSNPTIFLDKFKIIDLRPSGSGAKKGHGFPTIAPMEISHLINENEFSKFMKSFNRVFNYFFLLLFNVVFLIAGIIFPIFISRISILWAVVGSVGIFIIGGIFYCCINKYINGKRVGFISII
What are the official names of this protein?
Putative uncharacterized transmembrane protein DDB_G0292500.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL7_NITWN
Sequence: MADLQKIVDDLSALTVLEAAELAKLLEEKWGVSAAAAVAVAAAPGAGGGAPAAEEKTEFTVVLAAAGDKKIEVIKEVRAITGLGLKEAKDLVEGAPKPVKEGVAKDEAEKIKAQLEKAGGKVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RECO_LIMRD
Sequence: MARVTTQFTGIIMYRQDYRERDLLVKMLTDKIGPAMFFVKNAKKRGFRMTADILPFTHGTYIGSLDENGLSFINTASDTSQYKKIASDISKNAYVTYILALVDSAFNDGRSIGGWFKQVAAALDLIEKGLDEQIITNVIETQLLVAFGVAPVWDRCVVCGRNDLALDFSEQYGGMLCQNHWSLDEHRLYLDRKTAYYLQQFATINLQKLNSIRINPATKRRLQQVLDTLYDNEVGLNLKAKRFIKQMNKWEQNIGKLSMND
What is the function of this protein?
Involved in DNA repair and RecF pathway recombination.
What are the official names of this protein?
DNA repair protein RecO, Recombination protein O.
What is the protein family that this protein belongs to?
Belongs to the RecO family.
Protein: APAG_SHEHH
Sequence: MSQLTSSVRVDVKTEYIETQSSPDEDKYLFSYTITIHNLGSDDVTLKRRHWCITDSNGRKSEVHGTGVVGETPTIKPNSSYKYTSGTVLETPLGVMEGSYTMVDSNGDEFKAPISAFRLSIPGLLH
What are the official names of this protein?
Protein ApaG.
Protein: DEOD_STRPI
Sequence: MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRNMFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRELVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFYSNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEERQNTFTDMMKVGLETLIAE
What is the function of this protein?
Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
What are the official names of this protein?
Purine nucleoside phosphorylase DeoD-type, PNP.
What is the protein family that this protein belongs to?
Belongs to the PNP/UDP phosphorylase family.
Protein: FBCD1_MOUSE
Sequence: MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR
What is the function of this protein?
Acetyl group-binding receptor which shows a high-affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts.  Can facilitate the endocytosis of acetylated components (By similarity).
What are the official names of this protein?
Fibrinogen C domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: NIKR_ANAD2
Sequence: MLERIGISLEDGLLEQFDKLIAEKGYVNRSEAIRDLIRDALVQRAFTESSGREERVAVVTLVYDHDSSSLAQKLAHIQHENHRAVVSALHVHMDPHNCLEVLVLRGRGKDVVAMGESLVATRGVKYGKLVPATAGHDLG
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: GRXC4_ARATH
Sequence: MTMFRSISMVMLLVALVTFISMVSSAASSPEADFVKKTISSHKIVIFSKSYCPYCKKAKSVFRELDQVPYVVELDEREDGWSIQTALGEIVGRRTVPQVFINGKHLGGSDDTVDAYESGELAKLLGVSGNKEAEL
What is the function of this protein?
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase.  Reduces low molecular weight disulfides and proteins (By similarity).
What are the official names of this protein?
Glutaredoxin-C4, AtGrxC4.
What is the protein family that this protein belongs to?
Belongs to the glutaredoxin family. CPYC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRB_NOCSJ
Sequence: MKRHLLSAGDLSRDDAELVLRTAAELRELADRPIKKLPALRGRTVVNLFFEDSTRTRISFEAAAKRLSADVINFAAKGSSLSKGESLKDTALTLEAMGADAVVVRHGASGAPHRLAHSGWVRSSVVNAGDGTHEHPTQALLDAFTMWRHLGQGKEQSLDGRRIAIVGDVLHSRVARSNALLLKTLGAEVTLVAPPTLLPVGIDTWPVETSYDLDAVLPKADAVMMLRVQRERMSGGFFPTAREYSRRYGLDGRRMATLQDHTIVMHPGPMVRGMEITADVADSDRSVIVEQVTNGVAVRMAVLYLLLGGSEPAVSTSSTNEAEE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: CING_DANRE
Sequence: MSSLSADRKPPLDYGVQIRFIKDLDDAGGGFPDKSRLANGVGGVSNGTSSPSKYGVAVRVQGISGQPYVVLQDGEKGDSYGVQLKTQPQIQSAPPVVSQTSPYNTLLLGQREGARTPQGSYNPTDQPSSPDEDFGSPLRRPPGDGQAGTQGEAEPRTTERFTPSALAPKLDKKDNDAFNEAGLRKVKQNGIGSSLNGTGLNGSFPPPSSAQDEDQAPAIDTKSLAPINKLISRFGGGGGGSGDILNSEAQTRPRLDNRVRSQSADALNKPSEEASSTSPTINPYAPNTSATVPKLNSTKPSSTGSLGRDATSVAKVAAIPNFKPLAFNQSPKLFAPKEAPPAVPKKPVTPDLIKSQTTSIENGNGEDDQTKQAIYNILKEGSIEKEEAIKRKASLIHERFCGVKAPQISVTDSNMKTELEQAFGRNTQLQQQLDKSRRELQENQDQMVELRMDREGAESRLRQQEDQLAQLQEELRRTLENSPQSDSMQLDLLTVQAELSESQLLRQKLEDTLRQRERELTALKGALKDEVASHDKEMEALREQFSQDMDALRHSMETVSQSQLEIEEERQKVNASILAMEEELEGYKEQSEQWKKQFSSANQELLKAQQGKRELEEKLLAVVKQTDETDSNSVMKELQQCRDSLKKAQSELEKQKAETLKKQEELKSATRASEKRETELKAEIDRLINQLKKEKEELSKAIEKTQQPLVSDQTKDPESNLELQEANARLRERIARMTRLHSSVPDSSSSDALEEENRSLKTQLEESRRAASRLGVEKEELNRRLEEREREREALRRGKSDLEEQKRLLDRSLDKINKEMESMMGDSRQSVQVLQSQLEEFRDRSRRELQDAQRLSKDRLVELQRAQALLKTTQEEVSRVKKELLSCTEERDSTQLDKELLSSRLKNMETELQTDRSSQTDRSREIRLLEDKVKTLEIELDEEKSGAELLNERITRCREQVDQLRSELMQERSARHDLEMDKSALERQIKELKSRIADMGTQSRPSAGVTMLENKVQELEDRLRSEEREKNTIQAAQRRLDRKLKDVTATLDQERNQHAEQRDQLSLRVKALKRQLDESEGEVERLEGVRRKVLRELEEQRELQAALQAKVNAMDNELRKIQQSRRSTLGSTLSSDEEDNYSDTKSITSILTDSPLQTTSC
What is the function of this protein?
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.  Note=Localizes to the apical junction complex composed of tight and adherens junctions.
What are the official names of this protein?
Cingulin.
What is the protein family that this protein belongs to?
Belongs to the cingulin family.
What are the subcellular locations of this protein?
Cell junction, tight junction.
Protein: BNL2B_EBVA8
Sequence: MRPGRPLAGFYATLRRSFRRMSKRSKNKAKKERVPVEDRPPTPMPTSQRLIRRNALGGGVRPDAEDCIQRCHPLEPALGVSTKNFDLLSLRCELGWCG
What are the official names of this protein?
Uncharacterized protein BNLF2b.
What is the protein family that this protein belongs to?
Belongs to the lymphocryptovirus BNLF2B family.
Protein: CAPP_PROM0
Sequence: MESFRQIKNNNVDLISNNDPLDKNRLLIEDLWESVLREECPDDQAERLIQLKELSYSKQIDGNSSKTFKNEIVDIVNSMDLAESIAAARAFSLYFQLVNILEQRVEEDRYIQSFTNKDVQKSPDNLDPFAPALARQNAPVTFRELFYRLRKLNVPPGKLEELLQEMDIRLVFTAHPTEIVRHTIRHKQTRVANLLKKIQIEQFLTKDEKISLKTQLKEEVRLWWRTDELHQFKPSVLDEVDYSLHYFQQVLFNAMPQLRGRITEALTENYPDVQLPPESFCNFGSWVGSDRDGNPSVTPDITWRTACYQRQLMLDRYIVATSNLRDQLSVSMQWSQVSSSLLESLETDRVKFPEIYEARATRYRSEPYRLKLSYILEKLRLTQERNNLLADSGWKFDFEGEIDNKNIDKVENLYYKSVNEFTYDLELIKNSLISTDLTCDSVNNLLTQVHIFGFSLASLDIRQESTRHSDAIQELTNYLDLSVQYDQMSEEEKIKWLIDELNTKRPLIPSDVNWTKTTEETFSVFKMVKRLQQEFGSRICHSYVISMSHSASDLLEVLLLAKEMGLLDQDSQKSKLLVVPLFETVEDLQRAPEVMEKLFKLDFYKSLLPKVGESFKPLQELMLGYSDSNKDSGFVSSNWEIHRAQIALQNLSSRNNILLRLFHGRGGSVGRGGGPAYQAILAQPSGTLKGRIKITEQGEVLASKYSLPELALYNLETVTTAVIQNSLVNSRLDATPEWNQLMSRLAETSRSHYRKLVHENPDLLNFFQEVTPIEEISKLQISSRPARRKKGAKDLSSLRAIPWVFGWTQSRFLLPSWFGVGTALSAELNSDPQQIELLRVLHQRWPFFRMLISKVEMTLSKVDLEVARYYVDTLGSKENKDSFDNIFEVISKEYNLTKSLILEITGKNKLLESDRDLKSSVSLRNKTIIPLGFLQVSLLRRLRDQTRQPPISEFLIDKDESRRAYSRSELLRGALLTINGIAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: ATPG_SPIOL
Sequence: MACSLSFSSSVSTFHLPTTTQSTQAPPNNATTLPTTNPIQCANLRELRDRIGSVKNTQKITEAMKLVAAAKVRRAQEAVVNGRPFSETLVEVLYNMNEQLQTEDVDVPLTKIRTVKKVALMVVTGDRGLCGGFNNMLLKKAESRIAELKKLGVDYTIISIGKKGNTYFIRRPEIPVDRYFDGTNLPTAKEAQAIADDVFSLFVSEEVDKVEMLYTKFVSLVKSDPVIHTLLPLSPKGEICDINGKCVDAAEDELFRLTTKEGKLTVERDMIKTETPAFSPILEFEQDPAQILDALLPLYLNSQILRALQESLASELAARMTAMSNATDNANELKKTLSINYNRARQAKITGEILEIVAGANACV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, chloroplastic, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: THIG_PSEPW
Sequence: MSNVRSDKPFTLAGRTFQSRLLVGTGKYRDMEETRLAIEASGAEIVTVAVRRTNLGQNPGEPNLLDVLPPDRYTILPNTAGCYDAVEAVRTCRLARELLDGHNLVKLEVLADQKTLFPNVIETLKAAEVLVKDGFDVMVYTSDDPIIARQLAEAGCIAVMPLAGLIGTGLGICNPYNLQIILEESKVPVLVDAGVGTASDATIAMEMGCEAVLMNSAIAHAQQPVLMAEAMKHAIVAGRMAYLAGRMPKKLYASASSPLDGLIK
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_BEII9
Sequence: MAREGEGGGRGGREERDSEFVDRLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGYGHGKAREVPEAIRKATESAKRALIRVPLREGRTLHHDVNGRHGAGRVVLRAAPAGTGIIAGGPMRAVFETLGMHDVVAKSQGSSNPYNMIRATFDALQREDSPRAVAARRSLKVSVLQGRRLGGDTETAAEG
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: DHI1L_MACFA
Sequence: MKVLLLTGLGALFFAYYWDDNFDPASLQGARVLLTGASAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGVPAGTRARTPQATRWLMQVNFLSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDSFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRGVTRVKAAPGPKAALAVIRGGATRAAGVFYPWRFHLLCLLRRWLPRPRAWFIRQDLNVTAAAAA
What are the official names of this protein?
Hydroxysteroid 11-beta-dehydrogenase 1-like protein, 11-beta-hydroxysteroid dehydrogenase type 3, 11-DH3, 11-beta-HSD3.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_SHEB9
Sequence: MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTNIYVATDDDRIKAAVEGFGGKVVMTSPDAASGTDRINDAINQLGLKDDDLVINLQGDQPLIDPTSIEQVISLFERHPGEFEMATLGFEIVNKAELDDPMHVKMVFDNNNYALYFSRSRIPFGRDTQDYPVYKHLGVYAYTRKFVQAFAALPLGRLEDLEKLEQLRALEYGHKIKIAISAFDSIEVDTPEDIRKCEQRLAVD
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MGSA_BACAH
Sequence: MKIALIAHDKKKDDMVSFAYAYKPIFEQHELFATGTTGLRIMEATGLVVTRYQSGPLGGDQEIGAMIAKNDLDMVIFFRDPLTAQPHEPDVNALLRLCDVYAIPLATNMASAEMLMHALERGDLDYRKLRK
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: CAPP_SALPA
Sequence: MNEQYSALRSNVSMLGKVLGETIKDALGEHILDRVETIRKLSKSSRAGNEANRRELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPDLNDATIKKAVESLSLELVLTAHPTEITRRTLIHKMGEINNCLKQLDNTDIADYERHQVMRRLRQLIAQSWHTDEIRKQRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVDFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIHVLVSELSMVDATPELLALVGEEGASEPYRYLMKKLRARLMATQSWLEARLKGEELPKPAGLLTQNEQLWEPLYACYQSLQACGMGIIANGELLDTLRRVKCFGVPLVRIDIRQESTRHTEALGEITRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWEPSNDTREVLETCKVIAEAPKGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNADDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLEGGLRVTEQGEMIRFKYGLPEVTVSSLSLYTSAILEANLLPPPEPKDSWRHIMDELSVISCETYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFSKADLWLADYYDQRLVAKTLWPLGKELRDLLEEDIKVVLAIANDSHLMADLPWIAESIQLRNVYTDPLNVLQAELLYRSRLTEEQGKSPDPRVEQALMVTIAGVAAGMRNTG
What is the function of this protein?
Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, PEPC, PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
Protein: E4PD_SALA4
Sequence: MTVRIAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRHEREQLFVGDDVIRILHERTLADLPWRELGVDVVLDCTGVYGNREHGEAHIAAGAKKVLFSHPGSNDLDATVVFGVNQNQLRAEHRIVSNASCTTNCIIPVIKLLDDAYGIESGTVTTIHSAMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLAAGITRIFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKASEVNQLLQKAAQGAFHGIVDYTESPLVSIDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMAAVGFRLDASASTKL
What is the function of this protein?
Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.
What are the official names of this protein?
D-erythrose-4-phosphate dehydrogenase, E4PDH.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_MALP2
Sequence: MEIKMKNNFETVIGIEVHVVLSSKTKMFSSSKSSHTDPKNTNISPIDLGHPGTMPLPNKRCIEKAIVLAKALDMEIEKNISFDRKNYFYQDLPKGFQITQQFHPIGKNGKIYLDENNFVDIERIHLEEDTAKQTKEDDGTILLDYNRSGIPLIEIVTKPCIKSSTEAGLFLKKLRRILTFNDISDAKMEEGSLRVDVNISVKPIGSKEFGTRVEIKNINSINNVEKAIEYESNLQAEQILKQEEVLMATKRFNDKTLTTEFMRLKTTNVDYHYMVEPNIFVRKISDDFITDVIKNNYTDIKSIEADLLKNNVSQEFINLLMDDYELFQKFKFINDEIKDCNEVIKWLCVEFVGSLNKVNLKLKDATDFQLNQLLKMMKYLLKDASINAKQGKEIVKLLIETNKDIDTLIEENNFKQITDKNVLRPILEKYVEANKPMLDQYDSRPERVEKFFIGMVMKDTNGQANPNVVTEIFNEILKLNK
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: LAG3_CAEEL
Sequence: MDDLSEFFVIEEMFISEPSVAGMKPSTSKTTHSPPPEEPTAPFVNDNLPNPEDEPTIGDLNAFHSGEELHRQRSELARANYEKARPEMIANQRAVTAHLFNRYTEDEERKRVEQQKNKEAMNASTSAPTSSRNGGQSVENRKRRNDVVVAPPTSEEEWKRAQQQHWMGQQQPQMQFQMQQQYHSQQQQYIMMQQQHHHMTGMQQIHHQMPSTSSADSIRSVPTPASSMHQPSPAEMRNGCGMSRNATMDMTCSPMSGGQPIVDENNLAVPEGEWFDKLALAVAEQYNVDTILGPDTYDTFLAELDFSSSESPTKQSPMEMNGDRMPSTAPPPAQNPQHIAQLQQQQNKMRLMQQQQQEMQRIEQQRRQQIMQQQQQQQQQEHQRQQMLLQQQQQQQQMQQHHQMNGGGQFATQAHQQAAYMQQMQRMEQIRHQQQQAQQHQQAQQQHQQQAQHHQMGYGIPNGYPQQMHMHPPAYGAHHMPQPTAFANIN
What is the function of this protein?
glp-1/Notch and lin-12/Notch proteins promote signaling by recruiting lag-3 to target promoters, where it functions as a transcriptional activator, probably as part of a complex with a Notch intracellular domain (NICD) and the transcription regulator lag-1 (PubMed:10830967, PubMed:10884418, PubMed:16530045).  Involved in the p53-mediated germ-cell apoptotic response to DNA damage, perhaps acting as a transcriptional activator (PubMed:17317671).  May regulate phosphatase lip-1 mRNA transcription downstream of glp-1 (PubMed:16319922).
What are the official names of this protein?
Protein lag-3, Abnormal cell lineage protein 3, Abnormal germline proliferation protein 3.
What are the subcellular locations of this protein?
Nucleus.