PharMolix/UniProtQA huggingface dataset:
Protein: SECA_HAEIN
Sequence: MSILTRIFGSRNERVLRKLKKQVVKINKMEPAFEALSDDELKAKTQEFRDRLSGGETLQQILPEAFATVREASKRVLGMRHFDVQLIGGMVLTNRCIAEMRTGEGKTLTATLPCYLIALEGKGVHVVTVNDYLARRDAETNRPLFEFLGMSVGVNIPGLSPEEKRAAYAADITYATNSELGFDYLRDNLAHSKEERFQRTLGYALVDEVDSILIDEARTPLIISGQAENSSELYIAVNKLIPSLIKQEKEDTEEYQGEGDFTLDLKSKQAHLTERGQEKVEDWLIAQGLMPEGDSLYSPSRIVLLHHVMAALRAHTLFEKDVDYIVKDGEIVIVDEHTGRTMAGRRWSDGLHQAIEAKEGVDVKSENQTVASISYQNYFRLYERLAGMTGTADTEAFEFQQIYGLETVVIPTNRPMIRDDRTDVMFENEQYKFNAIIEDIKDCVERQQPVLVGTISVEKSEELSKALDKAGIKHNVLNAKFHQQEAEIVAEAGFPSAVTIATNMAGRGTDIILGGNWKAQAAKLENPTQEQIEALKAEWEKNHEIVMKAGGLHIIGTERHESRRIDNQLRGRSGRQGDPGSSRFYLSLEDGLMRIYLNEGKLNLMRKAFTVAGEAMESKMLAKVIASAQAKVEAFHFDGRKNLLEYDDVANDQRHAIYEQRNHLLDNDDISETINAIRHDVFNGVIDQYIPPQSLEEQWDIKGLEERLSQEFGMELPISNWLEEDNNLHEESLRERIVEIAEKEYKEKEALVGEDAMRHFEKGVMLQTLDELWKEHLASMDYLRQGIHLRGYAQKDPKQEYKKESFRMFTEMLDSLKHQVITALTRVRVRTQEEMEEAERARQEMAARINQNNLPVDENSQTTQNSETEDYSDRRIGRNEPCPCGSGKKYKHCHGSRVARQ
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CH60_XANCH
Sequence: MAAKDIRFGEDARTRMVRGVNVLANAVKATLGPKGRNVVLEKSFGAPTITKDGVSVAKEIELADKFENMGAQMVKEVASKTNDNAGDGTTTATVLAQALIREGAKAVAAGMNPMDLKRGIDQAVKAAVVELKNISKPTTDDKAIAQVGTISANSDESIGNIIAEAMQKVGKEGVITVEEGSGLENELDVVEGMQFDRGYLSPYFINNQQSQSADLDDPFILLHDKKISNVRDLLPVLEGVAKAGKPLLIVAEEVEGEALATLVVNTIRGIVKVVAVKAPGFGDRRKAMLEDMAVLTGGTVISEEVGLALEKATIKDLGRAKKVQVSKENTTIIDGAGDTAAIESRVGQIKTQIEDTSSDYDREKLQERVAKLAGGVAVIKVGASTEIEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRALVAVGELKGANEDQTHGIQIALRAMEAPLREIVANAGEEPSVILNKVKEGSGNYGYNAANGEFGDMVQFGILDPTKVTRSALQNAASIAGLMITTEAMVADAPKKDEPVMPAGGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_PROM3
Sequence: MTDRCLASINAALTDSDPAIAGLIDQERQRQETHLELIASENFTSQAVMQAQGSVLTNKYAEGLPHKRYYGGCEHVDAIEELAIERARRLFGAAWANVQPHSGAQANFAVFLALLQPGDTIMGMDLSHGGHLTHGSPVNVSGKWFKVVHYGVEPDSQQLDMEAVRQLALKERPQLIICGYSAYPRTIDFAAFRSIADEVGAYLLADMAHIAGLVAAGVHPSPIAHCDVVTTTTHKTLRGPRGGLILCRDADFGRKFDKAVFPGSQGGPLEHVIAAKAVALGEALQPEFHAYSCQVVANAQVLAGRIQERGIAVVSGGTDNHLVLLDLRSIGMTGKVADLLVSDVNITANKNTVPFDPESPFVTSGLRLGTAALTTRGFDEEAFREVADVIADRLLKPQDESIKAQCLERVRQLCGRFPLYRGSL
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDRP_STRA1
Sequence: MEDQLTIFIISDSLGETAKAIAKACLSQFPGHDDWHFQRFSYINSQERLEQVFEEASQKTVFMMFSLVDVALASYAQKRCESEHYAYVDLLTNVIQGISRISGIDPLGEPGILRRLDNDYFKRVESIEFAVKYDDGRDPRGILQADLVIIGISRTSKTPLSMFLADKNIKVINIPLVPEVPVPKELRMIDSRRIIGLTNSVDHLNQVRKVRLKSLGLSSTANYASLERILEETRYAEEVMKNLGCPIINVSDKAIEETATIILEILKTNGQVAKNL
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RSL4_ARATH
Sequence: MDVFVDGELESLLGMFNFDQCSSSKEERPRDELLGLSSLYNGHLHQHQHHNNVLSSDHHAFLLPDMFPFGAMPGGNLPAMLDSWDQSHHLQETSSLKRKLLDVENLCKTNSNCDVTRQELAKSKKKQRVSSESNTVDESNTNWVDGQSLSNSSDDEKASVTSVKGKTRATKGTATDPQSLYARKRREKINERLKTLQNLVPNGTKVDISTMLEEAVHYVKFLQLQIKLLSSDDLWMYAPLAYNGLDMGFHHNLLSRLM
What is the function of this protein?
Transcription factor involved in the regulation of root hair elongation (PubMed:20139979, PubMed:27251390, PubMed:27452638).  Is sufficient to promote postmitotic cell growth in root-hair cells and is a direct transcriptional target of RHD6 and RSL1 (PubMed:20139979).  Involved in the regulation of root hair elongation in response to low phosphate (PubMed:27251390, PubMed:29651114).  Controls root hair cell growth by regulating the expression of genes encoding proteins involved in cell signaling, cell wall modification and secretion (PubMed:27452638).
What are the official names of this protein?
Transcription factor RSL3, Basic helix-loop-helix protein 54, AtbHLH54, bHLH 54, ROOT HAIR DEFECTIVE 6-LIKE 4, Protein RHD SIX-LIKE 4, Transcription factor EN 114, Transcription factor bHLH54, bHLH transcription factor bHLH054.
What are the subcellular locations of this protein?
Nucleus.
Protein: RFC4_ORYSJ
Sequence: MDASSSSAPDLADAYDIPWVEKYRPTRVADVGGNSDAVARLQDIARDGNMPNLILSGPPGTGKTTSILSLAHELLGPSYREAVLELNASDDRGLDVVRNKIKMFAQKKVTLQPGRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFSRLSDQEILGRLMIVVAAEKVPYVPEGLEAIIFTADGDMRQALNNLQATVSGFRFVNQENVFKVCDQPHPLHVKNMVKNVLDGKFDEACSALKQLYDLGYSPTDIITTLFRVIKNYDMAEYLKLELLKETGFAHMRICDGVGSFLQLSGLLAKFALVRETAKAS
What is the function of this protein?
May be involved in DNA replication and thus regulate cell proliferation.
What are the official names of this protein?
Replication factor C subunit 4, OsRFC4, Activator 1 subunit 4.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family.
What are the subcellular locations of this protein?
Nucleus.
Protein: GSTU4_ARATH
Sequence: MAEKEEDVKLLGFWASPFTRRVEMAFKLKGVPYEYLEQDIVNKSPLLLQINPVYKKVPVLVYKGKILSESHVILEYIDQIWKNNPILPQDPYEKAMALFWAKFVDEQVGPVAFMSVAKAEKGVEVAIKEAQELFMFLEKEVTGKDFFGGKTIGFLDLVAGSMIPFCLARGWEGMGIDMIPEEKFPELNRWIKNLKEIEIVRECIPPREEQIEHMKKVVERIKSA
What is the function of this protein?
May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides.
What are the official names of this protein?
Glutathione S-transferase U4, AtGSTU4, GST class-tau member 4, Glutathione S-transferase 22.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Tau family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: T217B_HUMAN
Sequence: MNVRMFSLMVGIFSVLNTTQFFIFDLNQKTHICYEAKFSIYVDSKSELVTWTLFHRANISTGLSLTTIIIGCFLFYCIHKNIYMGLLIYAMWIITYELINFSIVLLLNGIIKDHFKTLSYLHWIFQISHMLLHFFCLPFIVKHAYNLYKESQTVGRKRRHRLCSTIAVNS
What are the official names of this protein?
Putative transmembrane protein 217B.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RUTA_CAUSK
Sequence: MEIGVFIPIGNNGWLISEAAPQYMPSFALNKEIVQKAEKYGFDFALSMIKLRGFGGKTQFWEHNLESFTLMAGLAAVTDRIKIFATAATLTLPPAIVARMASTIDSIAPGRFGINLVTGWQKAEYDQMGLWPGEQHYTDRYNYLAEYATVLRELLETGVSDFKGKYFQMTDCRVSPHPKDTKLICAGSSNEGLAFTAQYADYSFALGKGTNTPTAFGGVNDRLKAAADKTGRDVASYILFMIIADETDEAAMAKWQAYRAGADQEALAWLTNQAAPNAAAGATTNTAQLAAPESAVNLNMGTLVGSYENVARMLDEVAAVEGTAGVLLVFDDFVAGVENFGTKIQPLMTSRAGV
What is the function of this protein?
Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide.  The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN.  Requires the flavin reductase RutF to regenerate FMN in vivo.
What are the official names of this protein?
Pyrimidine monooxygenase RutA.
What is the protein family that this protein belongs to?
Belongs to the NtaA/SnaA/DszA monooxygenase family. RutA subfamily.
Protein: VATE_YEAST
Sequence: MSSAITALTPNQVNDELNKMQAFIRKEAEEKAKEIQLKADQEYEIEKTNIVRNETNNIDGNFKSKLKKAMLSQQITKSTIANKMRLKVLSAREQSLDGIFEETKEKLSGIANNRDEYKPILQSLIVEALLKLLEPKAIVKALERDVDLIESMKDDIMREYGEKAQRAPLEEIVISNDYLNKDLVSGGVVVSNASDKIEINNTLEERLKLLSEEALPAIRLELYGPSKTRKFFD
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:8416931).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:8416931, PubMed:2145285).
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E, V-ATPase 27 kDa subunit, Vacuolar proton pump subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RL31_ECOSM
Sequence: MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRDVATGGRVDRFNKRFNIPGSK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: F210A_XENTR
Sequence: MHLLRTLLLRSNTSNISLLTKCAFRACPLQKWPVSLRSGCQVSVLPTQQKKWLHSQPKQQDSSTKTPVHDLPSGSQHQSEESSPSAKSSISTDTSIVAETDPLQDQSIGLLKRFKKTFKQHGKVLIPVHLVTSSFWFGSFYYAAMKGVNVVPFLEFIGLPDVIVNILKNSQGGNALTAYAMYKIATPARYTVTLGGTSLSVKYLRKYGYLSTPPLVKDYFQDRMEETKELFTEKMEETRDIISGKMEETKDRISEKLQETKDRVAFRKKKNEEM
What is the function of this protein?
May play a role in the structure and strength of both muscle and bone.
What are the official names of this protein?
Protein FAM210A.
What is the protein family that this protein belongs to?
Belongs to the FAM210 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein. Mitochondrion. Cytoplasm.
Protein: GSTT4_RAT
Sequence: MGLELYMDLLSAPCRAVYIFARKNGIPFDFQFVDLLKGHHHSKEYIEINPLRKVPSLRDGKFILSESVAILCYLCRKYSAPSHWYPPDLHMRARVDEFMAWQHTAIQVPMSKILWIKLIIPMITGEEVPTERLDKTLDEVNKNIKQFEEKFLQDKLFITGDHISLADLVALVEMMQPMGTNHNVFISSKLAEWRMRVELAIGSGLFWEAHDRLVKLPSWDCSTLDPSIKMKICEFLQKYK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
What are the official names of this protein?
Glutathione S-transferase theta-4, GST class-theta-4.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Theta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_SHIB3
Sequence: MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVINMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: FIS_SHIFL
Sequence: MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN
What is the function of this protein?
Activates ribosomal RNA transcription.  Plays a direct role in upstream activation of rRNA promoters.
What are the official names of this protein?
DNA-binding protein Fis.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Fis family.
Protein: RL18_BREBN
Sequence: MFTKADKNKARKKRHLRIRKRVIGTTIRPRLNVFRSSKHIYAQLIDDATGVTLVSASSLDKELGLNNGANVEAATAVGTLIAKRAQEKGATEVIFDRGGYIYHGRIKALAEAAREAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: TM35B_MOUSE
Sequence: MSFRVGVLRVLLGVFFALTGAAKLFQVSAPVSQQMRALFEQFAEVFPLKVFGYQPDPISYQTAVGWLELLAGLLLVVGPPVLQEISNVLLILLMMGAVFTLVVLKEPLSTYVPAAVCLGLLLLLDSCHFLARTKGAVRCPSKKIPPAHGN
What are the official names of this protein?
Transmembrane protein 35B, ZMYM6 neighbor protein.
What is the protein family that this protein belongs to?
Belongs to the DoxX family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYLS_METMA
Sequence: MDKKPLNTLISATGLWMSRTGTIHKIKHHEVSRSKIYIEMACGDHLVVNNSRSSRTARALRHHKYRKTCKRCRVSDEDLNKFLTKANEDQTSVKVKVVSAPTRTKKAMPKSVARAPKPLENTEAAQAQPSGSKFSPAIPVSTQESVSVPASVSTSISSISTGATASALVKGNTNPITSMSAPVQASAPALTKSQTDRLEVLLNPKDEISLNSGKPFRELESELLSRRKKDLQQIYAEERENYLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDNDTELSKQIFRVDKNFCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTMLNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGDLELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSESYYNGISTNL
What is the function of this protein?
Catalyzes the attachment of pyrrolysine to tRNA(Pyl).  Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
What are the official names of this protein?
Pyrrolysine--tRNA ligase, Pyrrolysine--tRNA(Pyl) ligase, Pyrrolysyl-tRNA synthetase, PylRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_SHEB5
Sequence: MAKEDNIEMQGTILETLPNTMFRVELENGHVVIAHISGKMRKNYIRILTGDKVTVQLTPYDLTKGRIVFRAR
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMG9_HUMAN
Sequence: MSESGHSQPGLYGIERRRRWKEPGSGGPQNLSGPGGRERDYIAPWERERRDASEETSTSVMQKTPIILSKPPAERSKQPPPPTAPAAPPAPAPLEKPIVLMKPREEGKGPVAVTGASTPEGTAPPPPAAPAPPKGEKEGQRPTQPVYQIQNRGMGTAAPAAMDPVVGQAKLLPPERMKHSIKLVDDQMNWCDSAIEYLLDQTDVLVVGVLGLQGTGKSMVMSLLSANTPEEDQRTYVFRAQSAEMKERGGNQTSGIDFFITQERIVFLDTQPILSPSILDHLINNDRKLPPEYNLPHTYVEMQSLQIAAFLFTVCHVVIVVQDWFTDLSLYRFLQTAEMVKPSTPSPSHESSSSSGSDEGTEYYPHLVFLQNKARREDFCPRKLRQMHLMIDQLMAHSHLRYKGTLSMLQCNVFPGLPPDFLDSEVNLFLVPFMDSEAESENPPRAGPGSSPLFSLLPGYRGHPSFQSLVSKLRSQVMSMARPQLSHTILTEKNWFHYAARIWDGVRKSSALAEYSRLLA
What is the function of this protein?
Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (PubMed:19417104).  Is recruited by release factors to stalled ribosomes together with SMG1 and SMG8 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required for the efficient association between SMG1 and SMG8 (PubMed:19417104).  Plays a role in brain, heart, and eye development (By similarity).
What are the official names of this protein?
Nonsense-mediated mRNA decay factor SMG9.
What is the protein family that this protein belongs to?
Belongs to the SMG9 family.
Protein: NMT1_ASPPA
Sequence: MSTDKITFLTNWHATPYHAPLYLAQSKGYFKEEGLKVALLEPNDPSDVTEIIGSGKVDMGFKAMIHTLAAKARNFPVTSIGSLLDEPFTGVVYLKDSGITEDFRSLKGKKIGYVGEFGKIQIDELTKYYGMTADDYTAVRCGMNVTKAIIRGDIDAGIGLENVQMVELAEWLASQNRPRDDVQIVRIDQLAELGCCCFCSILYIANDAFLAANPEKVQKFMRAVKRATDYVLAEPAAAFEEYVDMKPIMGTPVNRKIFERSFAYFSRDLKNVSRDWAKVTNYGKRLGILDADFQPNYTNQYLSWTLDADSTDPLGDQKRMAELQKEVACEGGFKRLQVASSA
What is the function of this protein?
Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway.  Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP).  The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme.  The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.
What are the official names of this protein?
4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase, HMP-P synthase, Hydroxymethylpyrimidine phosphate synthase, Thiamine pyrimidine synthase.
What is the protein family that this protein belongs to?
Belongs to the NMT1/THI5 family.
Protein: TFF3_CANLF
Sequence: MEARVLWLLVVVLVLGSSSLAVAYQGLATNLCEVPPKDRVDCGYPEITSEQCVNRGCCFDSSIHGVPWCFKPLQDTECRF
What is the function of this protein?
Involved in the maintenance and repair of the intestinal mucosa.  Promotes the mobility of epithelial cells in healing processes (motogen) (By similarity).
What are the official names of this protein?
Trefoil factor 3, Intestinal trefoil factor.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Cytoplasm.
Protein: TRAF4_ECOLX
Sequence: MSRFQRLTKYVAIGGGAALLLAGAAYLAGAKVNTTKSIPVGLYWKSNAPVEKGAYVMFCPPQVGVFSDAKERGYIAGGFCPGDYGYMMKRVLAAKGDEVAITDAGVRVNGGLLPHSALIKADPSGRPLPRYQSDSYTLGTAEVLLMSDVSDTSFDGRYFGPVNRSQIITVIRPVLTW
What is the function of this protein?
Required for donor-specific phage sensitivity.  May be involved in pilus assembly.
What are the official names of this protein?
Plasmid transfer protein TraF.
What is the protein family that this protein belongs to?
Belongs to the peptidase S26C family.
What are the subcellular locations of this protein?
Periplasm.
Protein: CMOB_DICNV
Sequence: MNAALRKWHRAVTLLPALSVYDETAQRVFTAAYDRRHKSFEDWLTAIAQLPLIEPRAVHLNQAVVTAEGAGDEIAIETLLKALMPWRKGPFSLCGVSLDCEWRSDFKYQRLLDAGFSVSGKKVLDVGTGNGYFLYRFLGSGAQCAVGVDPSWLYFAQFLALQKFFQQNRAVYLPTTLDDLSLEGFDCVLAMGVLYHRRDPLAFLAQLRNAVVCGGDLVIETLVVDGDAQTVYMPKQEYVGMHNVWFLPSIAALCRWLERLNFRIELCSEAVETTINEQRRTRWVNSFSLADFLQRAPSAPPPKRAFVIAKRL
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: COAD_PROMH
Sequence: MKNKAIYPGTFDPITYGHIDILTRAAGMFDTVLLAIAASARKNPMFSLEERVALAKEVTQHLPNVEVVGFCELMANFAKKQQATILIRGVRSVSDFEYEWQLANMNRHFAPDLDSVFLLPSQNLSFVSSSLIKDVARHDGDVSTFLPEVVATAMLQKLGKR
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_CAMDR
Sequence: MTNIRKSHPLLKIMNDAFIDLPAPSNISSWWNFGSLLGVCLIMQILTGLFLAMHYTSDTTTAFSSVAHICRDVNYGWIIRYLHANGASMFFICLYIHVGRGLYYGSYTFSETWNVGMVLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVAVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGALLLMLALLILVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAFIPALHTSKQRSMTFRPISQCLFWVLVADLLTLTWIGGQPVEPPFIMIGQVASILYFSLILILMPVAGIIENRILKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RPPH_PSEAB
Sequence: MIDSDGFRPNVGIILANEAGQVLWARRINQEAWQFPQGGINDRETPEEALYRELNEEVGLEAGDVRILACTRGWLRYRLPQRLVRTHSQPLCIGQKQKWFLLRLMSDEARVRMDITSKPEFDGWRWVSYWYPLGQVVTFKREVYRRALKELAPRLLARD
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: FMT_BARHE
Sequence: MVLRLSFMGTPDFSVPILQALLDAGHDIAAVYSQPPRPAGRRGLKLIPSPVQNLAKAKSIPVFTPQTLKTAEQQTKFTELAVDVAIVVAYGLLLPKTILETPRFGCFNAHASLLPRWRGAAPIQRAIMAGDKETGMTIMKMDEGLDTGPIALSCAIPITDNTTTNELAHKLSHIGADLMIEMLSALEKGQLKLTAQSGENITYASKIKKEETRIDWTKPAEFIHRYIRALSPFPGCWCNMNIAGREERVKILGSRLTTRPSLEIGRIEKGPDSLLIHCGQGCLEVTYLQRSGGKVLECATFLQGAHISAVF
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: MEPA_SALEP
Sequence: MKKTAIALLAWFVSSASLAATPWQKITHPVPGAAQSIGSFANGCIIGADTLPVQSDNYQVMRTDQRRYFGHPDLVMFIQRLSHQAQQRGLGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRWSQAQLLRPQALDLVSRDGKHVVPSRWSSDIASLIKLAAQDNDVTRIFVNPAIKQQLCLDAGNDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVL
What is the function of this protein?
Murein endopeptidase that cleaves the D-alanyl-meso-2,6-diamino-pimelyl amide bond that connects peptidoglycan strands.  Likely plays a role in the removal of murein from the sacculus.
What are the official names of this protein?
Penicillin-insensitive murein endopeptidase, D-alanyl-D-alanine-endopeptidase, DD-endopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M74 family.
What are the subcellular locations of this protein?
Periplasm.