PharMolix/UniProtQA huggingface dataset:
Protein: PUM2_XENLA
Sequence: MNVPCVVGMNEVAWQESRGIMHASSGQEALGVGVGMVPSGVSSAGQAHGNNPHAMPPGAPSAQVPLSGRSQDDATVGYFFQRQAGEQLNGYSNKHRWPTGDSIDAAVRSVDEMNHDFQALALESRGMGELLPAKKFWEHEDPAKDGQKGMFLADEWRENTWGASHHSMSQPIMVQRRPGQGFHGNHDVASVLSPRSESGGLGVSMVEYVLSSSPADKLDPRFRKGVFSVRDCELDGPEKGEQKCKASPFEEEKKRDLISADTDNVSKLNGRGLPNGIESDCKDFNRTPGSRQASPTEITERIGPNSISAEVLGQHQNPMSNKPLSDEFPSTESQNLDGMEQVGLHSLQFDYPGNQIQMDSAGAGVGLFDYNTQQQMFQRQNALTVQQLTAAQQQQQQFTLAAAQQPHLAGMFSTGLAPAAFVPNPYIISAGHPGADPYTTLAGPAVVSPQYYGIPWGVYPAGLFQQQAAAAAQAANSNNQQAATQASQGQQQVMRATSNQRPLTPNQAQQGQQPESLAAANQAQIFGQGLATSMPGYQLLTPTAYYDQTGALVVGPGARAGLAAQVRLVASAPVLLSPAAAQAATATGANSLTGATNGMFRQMGPQQQQQQQQQQHQQQQQQPNANLHSNSFYGNSTMSNNSQSSSLFSPGPGQPGSTSLGFGSSNSLGAAIGSAFGGFGSSVGNSAGSSGSRRDSLSASCDLYKRSSSSLAAIGQPYYNSLGFSSSPSPISMPLPSQTSGHSLTPPPSLSSHGSSSSLHLGGLTNGSGRYFSAAPGAEAKYRSAANTSSFFSSNSQLFPPSRLRYNRADIMPSGRSRLLEDFRNNRFPNLQLRDLMGHIVEFSQDQHGSRFIQQKLERASPAERQLVFSEILQAAYQLMTDVFGNYVIQKFFEFGSMDQKLALATRIRGHVLPLALQMYGCRVIQKALESISTDQQSEMVRELDGHVLKCVKDQNGNHVVQKCIECVTPQSLHFIIEAFKGQVYVLSTHPYGCRVIQRILEHCTPEQTLPILEELHQSTEQLVQDQYGNYVIQHVLEHGRSDDKSKIVCEVRGQVLVLSQHKFASNVVEKCVTHSSRTERAFLIDEICCQNDGPHSALYTMMKDQYANYVVQKMIDMAEPAQRKIIMHKIRPHITTLRKYTYGKHILAKLEKYYMKNSPDLGLLVGPSNGML
What is the function of this protein?
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets.  Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE).  Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of deadenylase complexes leading to translational inhibition and mRNA degradation (PubMed:21098481).  Also mediates deadenylation-independent repression by promoting accessibility of miRNAs.
What are the official names of this protein?
Pumilio homolog 2, Pumilio-2.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, P-body. Cytoplasmic granule.
Protein: ANMK_BACC1
Sequence: MYVAGVMSGTSLDGIDVALVHIEGSGVGSKVELIHFTTVPFRNDIKNEIQQVLSIKNSNVQLICSLNFKLGLCFAKAVKEVCKEANFSLEQLDLIGSHGQTIYHQPKPEGNMISSTLQIGEPAVIAYETNTTVISNFRTMDMAAGGQGAPLVPYSEIILYRHPTKNRLLQNIGGIGNVTVIPSQKSDQNVIAFDTGPGNMIIDEVCQRLFQLPYDQNGEIAEQGEVVDEILTYCMNHSFLKMNPPKSTGREQFGEEFVSQLLKRYEKHSKENILTTVTMFTASSIVHHYKEFILPYYEIDEVILGGGGSYNDTLVEMIRYGLKDEKCTIFIQEDIGYSSEAKEAIAFAILANETYHRNPSNVPSATGAMQSVVLGNITFPPIR
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: ZN513_RAT
Sequence: MPRRKQSHPQPVKCEGVKVDTEDSFDEGPGALVLESDLLLGQDLEFEEEEEEEEGDGHNDQLMGFERDSEGDSQGARPGLPYGLSDDESGGGRALSAESEVEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPPLPPRLLYSCRLCAFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHTGEKPYRCPHCPFACSSLGNLRRHQRTHTGPPTPPCPTCGFRCCAPRPTRPPSPTEQEGTMPRRSEDALILPDLSLHVPPGGTSFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQELEEGEGSRLGTAMCGRCMRGESGGGGSGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCPYASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNLKRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQKVHGHGGAGGPGLSAPEGWAPPHSPPSVLSTRGSAALGATGSRALHTDSP
What is the function of this protein?
Transcriptional regulator that plays a role in retinal development and maintenance.
What are the official names of this protein?
Zinc finger protein 513.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MATK_TRIEE
Sequence: MEELQLQGYLEKDGSRQQNFLYPLIFQEYIYTLAHDHGLNSSIFYEPMEIVGLGYDNKSSSVLVKRLITQMYQQNSLIYSMNDFNQNRFVGHNNSFYSNFYSQMVSEGFAVIVEIPFSLRLVPSSEEIQIPKSQNLRSIHSIFPFLEDKLSHLNYVLDILIPYPIHLEILVQILQCWIQDVPSLHFLRFFLHEFHNWNNLNLITPTKSISVFSKENKRLFWILYNSYVSEYEFLFVFLRKQSYYLRSTSSRAFLERTHFYVKIEHLIDVCHNHFQKILWFFKDSFMHYVRYKGKAILASRGTYLLIKKWKCYLVNFWQYNFHFWSKPYRIHINPFSNYSFYFLGYISSVLINPSAVKNQMLENFYLVDTLTQKFDTIVPVIPLIGSLSKAKFCTILGHPISKPIWAELSDSDIMDRFGRICRNLSHYHSGSSKKQSLYRIKYILRLSCARTLARKHKSTVRNLLQRLGSGLLEEFFTEEEQVISPIFPKTTLFPLHGSHRERIWYLDIIRINDLANYLDWS
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DER_GEOSL
Sequence: MILPIVAIVGRPNVGKSTLFNRLVGRRKAIVDDMPGVTRDRNYETVTRFDVPFILIDTGGFEPESSDRLLQQMREQSRLAMEEADVILFLMDGRAGLNPADVEVVEMLRRVDKPVFFVVNKVDGETLEVAASEFYSLGVDNLLTISAEHNRGVRDLMDEVVAALPQRTTSPEERNATKIAVVGRPNVGKSSLVNRLLGYERVVANPTPGTTRDSVDTWFTCNKKRYLLIDTAGIRRKGKTTQKIEKYSVVDSLRSIERADVVLIVLNAEEGVTEQDERIAGYAFEAGKACIFVVNKWDAIEKDNSSVGRFVDKIRTEFKYLAFVPIVFVSAKTGQRLNRIMEEVEKVMAQYVKRVTTSELNRIFSAAVESHHHPLVMGRRVKFYFATQVGTRPPTFVIFTNRPDGMHFSYERYLVNKFREAFDFTGTPLRLLFRGRER
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ATPG_AGRRK
Sequence: MPSLKDLKNRIASVKATQKITKAMKMVAAAKLRRAQEAAEAARPYSQRMGAVLANITAAVSDADGAPLLMTGTGKSDVHLLVVCTAERGLCGGFNSQIARFARDHVRKLLAEGKTVKIFTVGKKGYDILRREYASLIIERKELRDVKRVGFENADALGKRIIEMFEAGEFDVCTLFYSEFKSVISQVPTGLQLIPASAPAVVEEDAAHKGAVYEYEPDAASILADLIPRNISVQIFRALLENVAGEMGSKMSAMDNATRNAGEMINKLTLSYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: C560_BOVIN
Sequence: MAALLLRHVGRHCLRAHLSPQLCIRNAVPLGTTAKEEMERFWSKNTTLNRPLSPHISIYGWSLPMAMSICHRGTGIALSAGVSLFGLSALLVPGSFESHLEFVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLTISQLHQSGVAVLVLTVLSSVGLAAM
What is the function of this protein?
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
What are the official names of this protein?
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial, Integral membrane protein CII-3, QPs-1, QPs1, Succinate dehydrogenase complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b560 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: LPXA_PSEF5
Sequence: MSLIDPRAIIDPTAVLADDVEVGPWSIVGAGVEIGEGTVIGPHVILKGPTRIGKHNRIYQFSSVGEDTPDLKYKGEETRLVIGDHNVIREGVTIHRGTVQDRSETTLGDHNLVMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILSGFTLVHQYCHIGAHSFSGMGTAIGKDVPAFVTVFGNPAEARSMNFEGMRRRGFSEDAIHALRRAYKTVYRQGLTVDQALAELAEPAAQFPEVAVFRDSIQSSTRGITR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL28_METPB
Sequence: MSRRCELTGKAVQVGHLVSHSNRKTKCRFLPNLCNVTLQSDALNRRVRLRVTAHALRSVEHRGGLDAFLIKAREIELSQTARLLKRDIEKKIAETATPAAA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: NDK_CYAP4
Sequence: MERTFLAVKPDGVQRALVGEIIRRFEAKGFKLVGLKLMNVSKDLAEQHYGEHKEKPFFPGLVQFITSGPVVAMVWEGKGVVASARKIIGATNPLNSEPGTIRGDYGVDIGRNIIHGSDAVETAQREIALWFQPAELVSWEPTLTSWIYE
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDFT_CYBJA
Sequence: MGKLLQLALHPDELASIVQFKLFRKNENARNPATESAELIRCYELLNLTSRSFAAVIEELHPELRNVIMVFYLVLRALDTVEVDMSIENSVKLPVLRQFHEKLDTKDWTFDGNSPNEKDRCVLVEFDRILGQYHELKPQYQKVIKEITEKMGNGMADYIENENFNSNGLLTIEDYDLYCYYVAGLVGDGLTQLIVLAKFGNSELSVNKQLFKSMGLFLQKTNIIRDYEEDQVDGRAFWPKEIWGKYANELSDFMKPENQSQGLWCISELVCNALDHVIDVLQYLALVEEQTSFNFCAIPQVMAIATLELVFQNPQVLTQHVKIRKGTTVSLILESRTLEGCARIFRRYLRKIHHKSHPSDPNYLRLGITIGKIEQFLDGMYPHYVPKGITPQTTSIRTQVVKRLQLDEPMKRDIDEEILKTRILLLSLGVAVFGVVYGVVRII
What is the function of this protein?
Catalyzes the condensation of 2 two farnesyl pyrophosphate moieties to form squalene.  It is the first committed enzyme of the sterol biosynthesis pathway.  Required for the biosynthesis of ergosterol.
What are the official names of this protein?
Squalene synthase, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RR3_PLAOC
Sequence: MGQKINPLGFRLGTTQNHHSVWFAQPKSYSEGLQEDQKIRDCIKNYVQKNKRIPLVEGIARIEIQKRIDLIQVIIYMGFPKLLIEDRPRGIEELQINLQKEFNSMNRKLNIAITRIAKPYGQPNILAEYIAGQLKSRVSFRKAMKKAIELTEQTDTKGIQVQIAGRIDGKEIARVEWIREGRVPLQTIRAKIDYCSYTVRTIYGVLGIKIWIFVDEE
What are the official names of this protein?
30S ribosomal protein S3, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ESD4_ARATH
Sequence: MGAVAINRKRSDESFNFINQQSTNPLRNSPYFQASKKRRFSFAMSEDSGKPASSNPTISRISRYPDAKAPLRREIHAPSRGILRYGKAKSNDYCEKDANFFVRKYDDAKRSALEALRFVNKGKDFVDLGDEVEKEEVVSDDSSVQAIEVIDCDDDEEKKNLQPSFSSGVTDVKKGENFRVEDTSMMLDSLSLDRDVDNDASSLEAYRKLMQSAEKRNSKLEALGFEIVLNEKKLSLLRQSRPKTVEKRVEVPREPFIPLTEDEEAEVYRAFSGRNRRKVLATHENSNIDITGEVLQCLTPSAWLNDEVINVYLELLKERETREPKKYLKCHYFNTFFYKKLVSDSGYNFKAVRRWTTQRKLGYALIDCDMIFVPIHRGVHWTLAVINNRESKLLYLDSLNGVDPMILNALAKYMGDEANEKSGKKIDANSWDMEFVEDLPQQKNGYDCGMFMLKYIDFFSRGLGLCFSQEHMPYFRLRTAKEILRLRAD
What is the function of this protein?
Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMOs to their mature forms and deconjugation of SUMO from targeted proteins.  Cleaves precursors of SUM1 and SUM2, but not of SUM3 or SUM5.  Able to release SUM1 and SUM2 from conjugates, but unable to cleave SUM3.  Acts predominantly as an isopeptidase, cleaving SUMO-conjugated proteins better than SUMO peptides.  Plays an important role in the control of flowering time.
What are the official names of this protein?
Ubiquitin-like-specific protease ESD4, Protein EARLY IN SHORT DAYS 4, AtESD4.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus membrane; Peripheral membrane protein. Note=The nuclear envelope localization is independent of the presence of the nuclear pore anchor NUA.
Protein: KHSE_CARHZ
Sequence: MVCVLIPATSANLGPGFDAVGMALSFYNEVSLGPSPKELEIEVFGDGAELISRDKNNLVYVAITKIFERLGKTPRNLKLTLKNRVPLARGLGSSAAAIVGGLVAANAYLGNPLPKDELLRLATELEGHPDNVAPALLGGVVVSGFDRDKVKYLKLPVPEVEVVVAIPKFQLKTADSRQILPAEIPFSQAVLNVNRVSFLIAAFCLKKYEYLQIGMEDYLHQPYRSQLIPGFYQVVEEAKKAGAYGVALSGSGPTVIALAREGKAVGRAIEETFLNFGVEAEIIYTRPEERGAIDLINYKGEGDC
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MINE_SHESH
Sequence: MSLLDYFKSKKKPNTAVTAKERLQIIVAHQRGERDAPDYFPQMKQEIIEVIKKYVHIDPDQVTVQLDQNDDKLSVLELNVTLPEEK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: TIM10_GIBZE
Sequence: MSFLGMGRPQPTSEQKIAAVESEMRMMADTYNRLQQSCQKKCVPNDYREGELNKGESVCLDRCTAKFLDTSMKVSEIMQQQGQALGGQQGGGGMF
What is the function of this protein?
Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.  Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane.  Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity).
What are the official names of this protein?
Mitochondrial import inner membrane translocase subunit TIM10.
What is the protein family that this protein belongs to?
Belongs to the small Tim family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Protein: SYC_STRT1
Sequence: MIKIYDTMTRSLRDFVPLTENTVNMYVCGPTVYNYIHIGNARSTVAFDTIRRYFEYRGYTVNYISNFTDVDDKIIKAANEVGISTKELSDKFITAFMEDTAQLGIKPATQNPRVINYMDEIIAFVSILIDKGFAYVSEGDVYFRVTKSNNYAKLANKTLEDLEIGASGRTDAETDRKEDPLDFALWKAAKEGEISWESPWGPGRPGWHIECSVMATEILGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKTFANYWMHNGFVNVDNEKMSKSLGNFVTVHDMLKTVDGQVLRFFLATQQYRKPINFTEKAIHDAEVNLKYLKNTHSLPLTEEVSQAELQAYLDAFQAAMDDDFNTANGVTVLFDMAKWINSGNYDETVKDAFEKILQVFGIVFEEETLDEDIEKLIEERQAARANKDFATADRIRDELAAQGIKLLDTKEGVRWTRD
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TX13A_MANRB
Sequence: MKIIHVLLLVAVVAITMSPSIMAESVAEADKPGQAKKIGLFDQIDKAAAAFMKLFEG
What is the function of this protein?
Induces paralysis 1 hour after injection into blowflies (L. caesar) but does not appear to be lethal.
What are the official names of this protein?
U13-myrmicitoxin-Mri1a, U13-MYRTX-Mri1a.
What are the subcellular locations of this protein?
Secreted.
Protein: CYH2_MOUSE
Sequence: MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP
What is the function of this protein?
Acts as a guanine-nucleotide exchange factor (GEF).  Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6.  Activates ARF factors through replacement of GDP with GTP (PubMed:18042453).  The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity).  Involved in neurite growth (PubMed:25326380).
What are the official names of this protein?
Cytohesin-2, ARF nucleotide-binding site opener, Protein ARNO, PH, SEC7 and coiled-coil domain-containing protein 2, CLM2, SEC7 homolog B, mSec7-2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm. Cell projection. Cell projection, growth cone. Cell junction, tight junction. Cell junction, adherens junction. Note=Recruited to the cell membrane through its association with ARL4A, ARL4C and ARL4D. Requires also interaction with phosphoinositides for targeting to plasma membrane (By similarity). In differentiating neuroblastoma cells, colocalizes with CCDC120 in both neurite shaft and growth cone areas.
Protein: CARA_ASPOR
Sequence: MFAARLFKAMPARASAFPSVNASIQSRFMATVRNGRVAHERATFTIRDGPIFHGKSFGARSNISGEAVFTTSLVGYPESLTDPSYRGQILVFTQPLIGNYGVPSAEKDQHGLLKYFESPHLQAAGVVVADVAEQYSHWTAVQSLGEWCAREGVPAISGVDTRAIVTYLREQGSSLARITVGEEYDADQDEAFVDPEQIHLVRQVSTKAPFHVSAADPQCHVAVIDCGVKENILRSLVSRGASITVFPYDYPIHKVAHHFDGVFISNGPGDPTHCQETAYHLRRLMETSQVPIFGICLGHQLLALAIGARTIKLKYGNRAHNIPALDMSTGRCHITSQNHGYAVDASTLPSDWKPYFVNLNDSSNEGMIHKTRPIFSTQFHPEAKGGPLDSSYLFDIYLDSVRKYKASQSAFHPTRDSLPSPLLVDLLAKERVGVQPTIGMQNVAAAAAAA
What are the official names of this protein?
Carbamoyl-phosphate synthase arginine-specific small chain, CPS-A, Arginine-specific carbamoyl-phosphate synthetase, glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COBQ_XANP2
Sequence: MARALMFQGTGSDVGKSLLVAGLARAFTLRGLKVRPFKPQNMSNNAAVTADGGEIGRAQALQARAARVPLSVHMNPVLLKPQGETGAQVVVQGRVHGTAKAAAYQGMKPSLLPFVLDSFDRLKAEADLVLVEGAGSASEVNLRTGDIANMGFARAADVPVVVIGDIDRGGVIASLVGTKAVIDAADAALIKGFVVNRFRGDPSLFATGMELIARQTGWAALGLVPHFSEAIRLPAEDALALSAPPAPKPRARTRICVPILPHVSNFDDLDPLDAEPSVEVRRIRPHETLPVDTDLVLLIGSKATIADLAALKAEGLHHDILAFARRGGHVMGLCGGYQMLGETIADPDGIEGEAKIARGLGLLKVHTVLSPEKRLVEVAGVALDPAVAAPFSGYEMHMGVTAGADAEQPFAVLSDGRQDGARSASGRVSGTYVHGLFASDAFRSGLLGALGGAPSQAAYEQGVEETLDRLAAHLAAHLDLDLLFSLAR
What is the function of this protein?
Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide.  NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.
What are the official names of this protein?
Cobyric acid synthase.
What is the protein family that this protein belongs to?
Belongs to the CobB/CobQ family. CobQ subfamily.
Protein: AROG_YEAST
Sequence: MSESPMFAANGMPKVNQGAEEDVRILGYDPLASPALLQVQIPATPTSLETAKRGRREAIDIITGKDDRVLVIVGPCSIHDLEAAQEYALRLKKLSDELKGDLSIIMRAYLEKPRTTVGWKGLINDPDVNNTFNINKGLQSARQLFVNLTNIGLPIGSEMLDTISPQYLADLVSFGAIGARTTESQLHRELASGLSFPVGFKNGTDGTLNVAVDACQAAAHSHHFMGVTKHGVAAITTTKGNEHCFVILRGGKKGTNYDAKSVAEAKAQLPAGSNGLMIDYSHGNSNKDFRNQPKVNDVVCEQIANGENAITGVMIESNINEGNQGIPAEGKAGLKYGVSITDACIGWETTEDVLRKLAAAVRQRREVNKK
What is the function of this protein?
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
What are the official names of this protein?
Phospho-2-dehydro-3-deoxyheptonate aldolase, tyrosine-inhibited, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, DAHP synthase, Phospho-2-keto-3-deoxyheptonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the class-I DAHP synthase family.
Protein: TRMFO_LACPL
Sequence: MASIPTVNVIGAGLAGSEAAWHIANMGVNVRLYEMRPNKMTPAHHTAQFAELVCTNSLRANQLANAAGLLKAEMRQMDSIVMQAAEHHAVPAGGALAVDRDTFSAEITAAITALPNVEIINEEITSLPDGITVVATGPLTAASLAKSIQAFNDEDDLHFFDAAAPILTKDSIDMDKVYLKSRYDRGEAAYLNCPMTEAEFDVFYDALIHAEMAEAHDFENSDVFEGCMPIEVMAQRGRQTMLFGPLKPVGLEDPKTGKQPFAVVQLRQDDAAGDLYNIVGFQTHLKWGEQKRVFSLIPGLENVEFVRYGVMHRNTFMKSPKLLTPTYQTQQRPDLFFAGQMTGVEGYIESAASGIVAGTNAARLALGLEPVVFPTDTMMGAMAHYITHTSASNFQPMNANFGIMPKLKQRIRDKRERNTAISERALADLTTFKDETLTVNN
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FPPS_HUMAN
Sequence: MPLSRWLRSVGVFLLPAPYWAPRERWLGSLRRPSLVHGYPVLAWHSARCWCQAWTEEPRALCSSLRMNGDQNSDVYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFYSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK
What is the function of this protein?
Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones.  FPP also serves as substrate for protein farnesylation and geranylgeranylation.  Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.
What are the official names of this protein?
Farnesyl pyrophosphate synthase, FPP synthase, FPS, (2E,6E)-farnesyl diphosphate synthase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Geranyltranstransferase.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_SHIB3
Sequence: MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ETDC_HUMAN
Sequence: MDKELPKASPSEPALNIKKSGKSFKCKKPTKNVQVFLINRQLGRNRSDTDLSKWLWMLP
What are the official names of this protein?
Embryonic testis differentiation protein homolog C.
Protein: RLMN_DICT6
Sequence: MNNILSFDIDEIRDILRGWGEPSYRADQIFDWVYKKLILNPSSMTNLPKGLRQKIAEYFSFDIPKVVKITGEGNTKKYLLELEDGENIETVLISHKNRNTVCVSVQVGCAIGCKFCATGLVGLRRNLNTHEIVGQIILIQKELFEKGDRISNVVYMGMGEPLLNYDNVVKSIRIINREWGLNIGSKHITLSTIGIVPKIYQLGEEDLKVRLAISLHAPNNELRSKIIPINKEYPIEKLLESAFYYAEKTGRRVTFEYVLIKNFNDREEHAIELAGLLKNKPVHVNLIPWNKVPEYPWETSDLKDIFKFKKILSDAGINVTLRISYGSRIKAGCGQLRALYLKSKGELK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.