PharMolix/UniProtQA huggingface dataset:
Protein: BPHA4_RHOJR
Sequence: MTSDIVVIGGGVAGVTAAQSLRSEGYDGRLVLIGKERELPYDRTALSKAVLAGDLADPPLLFPADWYDEWQIETVLDRTVLQVDVTRREVLLDGGPWLKVDRVLLATGASARVPSFSGSDLPGVATLRTADDVHRMRRDWEPGQRLVVVGGGLIGCEVATTARKLGLEVSILEASDELLQRVLGRRIGGWCRARLMELGISVVLNTGVAEFKGVDRITTVIGTDGRSFVADRAIVCVGAEPETAIAEQSGLACNRGILVNDSGGTAAEGVFAAGDVASWPLLTGGRRSLETYINSQREATAVASAMLGKAVHGPQLPLSWTEMAGHRIQMIGDIEGSGEYVMRGDPDDGPALLFRLSDGRVTAAVSVDAPRDFAMATRLVERGAQVGREVLGDTSMELRELNRAARERALIAE
What is the function of this protein?
Ferredoxin reductase component of the biphenyl dioxygenase system that catalyzes the stereospecific dihydroxylation of the aromatic ring of biphenyl, yielding a dihydrodiol compound.  Is likely involved in biphenyl degradation that allows growth of Rhodococcus sp.  strain RHA1 on biphenyl as the sole source of carbon and energy.  The dioxygenase system can also use naphtalene and 4-chlorobiphenyl (4-CB) as substrates, as well as some polychlorinated biphenyls (PCB) such as 2,2'-dichlorobiphenyl, 2,3-dichlorobiphenyl and 2,5,2'-trichlorobiphenyl.  It exhibits weak activity toward dibenzofuran and dibenzo-p-dioxin.  Electrons are transferred from NADH to the [2Fe-2S] cluster in BphA1 via FAD of BphA4 and [2Fe-2S] cluster of BphA3.
What are the official names of this protein?
Biphenyl 2,3-dioxygenase, ferredoxin reductase component, Biphenyl 2,3-dioxygenase, electron transfer component BphA4, Biphenyl dioxygenase system, ferredoxin--NAD(+) reductase component, BDO, ferredoxin reductase component.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase ferredoxin reductase family.
Protein: PER_DRONE
Sequence: SSTETPPSYNQLNYNENLLRFFNSKPVTAPVPVELDPPKVESSYVSSAREDARSTLSPVQGFEGSGGSGSSGNFTTGSNLHMSSVTNTSNAGTGTSGTGNSGDGGGGGAGDGPGSGAVPPVTLTESLLNKHNDEMEKFMLKNDRESRGWSGEKNKKSANDTLKMVEYSGPGPGHGHGIKRGGSHSWEGEANKPKQQLTLNAGGMPPLVDIHASSSSLSKCQTSVAGGGGGGGAGSASGTCGTGNNGAGGGGGSNAQSSTNQYTQSGLSCTQNINLWPPFSVGITTPTSVLSTHMAVAQSSFSPQHSLFPTFYYIPASIAASSPASGTSPNPRPHKHTHVHPSSEQPSTSQGAAATMPLQYMTGVMYPHPSLFYTHPAAAAATAMV
What is the function of this protein?
Essential for biological clock functions.  Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms.  Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system.  The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex.  Light induces the degradation of TIM, which promotes elimination of PER.  Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear at specific periods of the day. First accumulates in the perinuclear region about one hour before translocation into the nucleus. Interaction with Tim is required for nuclear localization (By similarity).
Protein: RF1_MYCLE
Sequence: MAQPVQSIDVLLIEHAELELALADPELHSNPAEARKAGRRFARLAPIVATHRKLISARDDLQTARELAAGDESFADEIAELESRIAELTTQLTDMLAPHDPHGPDDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWTVTVLDETTSDLGGYKDATLAISHKGASDGDAVDGVWSRMKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPEEIGEVHIDESDLRIDVYRSSGKGGQGVNTTDSAVRITHLPTGVVVTCQNERSQLQNKTRALQVLAARLQAMAEEQALANASADRASQIRTVDRSERIRTYNFPENRITDHRIGYKAHNLDQVLDGDLDALFDALSAADKQSRLQQV
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1536_HAEIN
Sequence: MDTSDNLARVGIRCSVRDLAPMVGNVPHFEQQQADYYNLFNLRRRKQPIQSAANFQNLFLIAALGSRGLTSAPLLGETLASIIYGEPLPISEGILHNLSANRAWVKKWLKGSKVE
What are the official names of this protein?
Uncharacterized protein HI_1536.
Protein: RGA3_SCHPO
Sequence: MIFRKSISKSPSSKGSTVCFRCGQAFQRRETPISFGGHMWHKDCFCCTKCDKGLEHSDQMLVQTSDGRPVCSSCAHTCTACRMRIKDYALMSGYDSYHRECFRCHDCRKQIIDSNFKRDNRTIFCNDCKQVRHPSRSSDESADYHNFEVDVTIKPTETKSSVESNKSLSIEIMSPQKPPLSPFGGSRDRLVSETPTNMSQAEGGNVPNDGQDSNLASNSADSLLPSAKNRSFSSFTSFESPMKYDDSFFPISPSISPLQKVNKQQQIESPTATFPLSKNTWKNRFHTFHKQSFTPVNDSSSSDSLKPTINEEALDDFAGSASPYKTMSLTDRAEPIVMNGHMRSLHNATSPFRPFSPSYRSSDTHSPRTRSPNVQTHKKTSSQPSDLSSFAQLLSPPQVLSPKPNGGGHKSFRHSHSLSETSQQTLVPSLGSNGEYHLPTNDHSSTPAQSERDSDVEELREQLENLTALTKKLSERLSSSTFDNSKFIRTEDKDTVRSAKLEICEKFFSFADVTDDPTLKDPKHQDLVAAANAYMAMLRESYGTEINNLLERRNELLDDYNNVQKILNESLEASVHLNTKNLELADLNNNLVKQIQHRVPPENQSNLEHTITTSSKNTTSSINPLTAVSSNSGQSSGRPGPLSPNLNVTTRIDIKGKKGSMHLQPRDVNRKVPFKSMHTKSKSADPVVGNEDRTQCDHVFHVNAIFKPSRCYICSESVWGSELRCFHCSISCHSRCLKRLFAESEHEKTMSETVSENSKWMPEMPTRMPPPGPSPTMFGRSLENQLKIEGSVLPQVIAMCVSCVDAHGLEVEGIYRISGSASQVRVLVDEFENGSIRMEHLTSDLFACTSVLKTYLHRLPEPVIPGTQYEELLEAEKIEKEEEKIERVVEVMKTLHPAHLSVFRFLIAHLGRVCKHAEKNLMNSKNVSTVFAPTLMRDKVNRFDLQHATKKSTALQFMLDNVDKILHNL
What is the function of this protein?
GTPase-activating protein for Rho-type proteins.
What are the official names of this protein?
Probable Rho-type GTPase-activating protein 3.
What are the subcellular locations of this protein?
Cell septum. Note=Cell poles and septum.
Protein: TMM98_RAT
Sequence: METVVIVAIGVLATIFLASFAALVVVCRQRYCRPRDLLQRYDSKPIVDLIGAMETQSEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTMGSGAKMKTSASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASEPDKSLPNPEGFLQEQSAI
What is the function of this protein?
Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination.  Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation.  The secreted form promotes differentiation of T helper 1 cells (Th1).
What are the official names of this protein?
Transmembrane protein 98.
What is the protein family that this protein belongs to?
Belongs to the TMEM98 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type II membrane protein. Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Note=Secreted by exosomes through a non-classical pathway.
Protein: TYSY_LACCA
Sequence: MLEQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTKKVPFGLIKSELLWFLHGDTNIRFLLQHRNHIWDEWAFEKWVKSDEYHGPDMTDFGHRSQKDPEFAAVYHEEMAKFDDRVLHDDAFAAKYGDLGLVYGSQWRAWHTSKGDTIDQLGDVIEQIKTHPYSRRLIVSAWNPEDVPTMALPPCHTLYQFYVNDGKLSLQLYQRSADIFLGVPFNIASYALLTHLVAHECGLEVGEFIHTFGDAHLYVNHLDQIKEQLSRTPRPAPTLQLNPDKHDIFDFDMKDIKLLNYDPYPAIKAPVAV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMNB_PSESP
Sequence: MANGEIISGFIAPHPPHLVYGENPPQNEPKSTGGWEQLRWAYERARASIEELKPDVLLVHSPHWITSVGHHFIGVDHLQGRSVDPIFPNLFRFDYSINFDVELSEACCEEGRKAGLVTKMMRNPRFRPDYGTITTLHMIRPQWDIPVVSISANNTPYYLSMEEGLGEMDVLGKATREAILKSGKRAVLLASNTLSHWHFHEEPVPPEDMSKEHPQTKIGYEWDMRMIELMRQGRMEEVFQLLPQFIEEAFAEVKSGAFTWMHAAMQYPNLPAELHGYGTVIGTGNAVVEWNLVKAGLARVAGKAA
What is the function of this protein?
Component of the 2-aminophenol 1,6-dioxygenase complex that catalyzes the ring fission of 2-aminophenol to produce 2-aminomuconic 6-semialdehyde.  AmnB seems to be the catalytic subunit of the complex.  The enzyme is also active toward 2-amino-p-cresol, 6-amino-m-cresol, 2-amino-m-cresol, 2-amino-4,5-dimethylphenol, 2-amino-4-chlorophenol, and catechol.
What are the official names of this protein?
2-aminophenol 1,6-dioxygenase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the LigB/MhpB extradiol dioxygenase family.
Protein: CYB_TAPTE
Sequence: MTNIRKSHPLIKIINHSFIDLPTPSNISSWWNFGSLLGMCLILQIITGLFLAMHYTSDTTTAFSSVAHICRDVNYGWIIRYLHANGASMFFICLFIHVGRGLYYGSYTFLETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVIVHLLFLHETGSNNPSGVSSDMDKIPFHPYYTTKDILGFLVLILMLLILVLFSPELLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALILSILILAIIPMLHTSKQRSMMFRPLSQCVFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLILVFMPLASAIENNFLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TIG_XANOR
Sequence: MQASIESTGNLERRLTFTLPQERLETHVGGRLRELARTTRIKGFRPGKVPTKVIEQRFGQQVRAEAMEGLLRETFDSAVREHSLRLAGNPRIDQGETDFDFVATFEVVPDFGDIDVTTLSVVRATAEVTDADIDQMIENLRLQRRIWNPVERGAQAGDLVALETWSQAGDERLPADGVETGSSVLGSGVMFDQIEKGLEGLTKGEEKTLSVDFPAEWRVPQLAGKTVQVHVKAVEVSEPVLPAVDKEFIKSFGVKSGDAEQFRADIRTNLERELKGALMNRLRREVGEQLIAAYAHVEMPPRLVENEARSMLAQQVEQVRRSGRDPGQVPADAHQGFMDAAAKRVLVGLLVGEVARRNELRLESRRVSDTLRLIASTYEEPEQVIEMYRNDPQLMNGLQSRVMEEQVIDWIAERAQHTEQSLSFQDAIRV
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: WALR_STAAB
Sequence: MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYEEEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTKPFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTHREFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEYIVTRRGVGYFLQQHE
What is the function of this protein?
Member of the two-component regulatory system WalK/WalR that regulates genes involved in cell wall metabolism, virulence regulation, biofilm production, oxidative stress resistance and antibiotic resistance via direct or indirect regulation of autolysins (By similarity).  Functions as a transcription regulator by direct binding to promoter regions (By similarity).
What are the official names of this protein?
Transcriptional regulatory protein WalR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPS_YERPA
Sequence: MSTAKLVKTKPSELLYTRNDVEEHVKVATIKRLNQMVIQFIDLSLITKQAHWNMRGANFVAVHEMLDGFRTALTDHLDTFAERAVQLGGVALGTAQVINDKTPLKSYPTNIHSVQEHLKALAERYAIVANDIRKAITEVEDENSADMFTAASRDLDKFLWFIESNIE
What is the function of this protein?
During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages.  It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction.  One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction.
What are the official names of this protein?
DNA protection during starvation protein.
What is the protein family that this protein belongs to?
Belongs to the Dps family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NFI_THEAC
Sequence: MLGSIACSMEFEDFDLYSYFYGLVKQIPEGYVTTYGDLAQALGDPIAARAVGYMLSINEDPDTIPCYRVVLHDGTVGNYTHPLGPMEKVRRLRADGIPVVDGMIENFDRYRFRDFKTDQPLRKMQQYQEYIARKYSESGAGEFRTVAAFDVSYEERRAFASMVIQDGSTIEAYVISDGINFPYIPGYLAFREFRFIKKLYRKADLLLIDGNGILHPRFAGLATHAGVLLDRASIGVAKHLTRSTRHQDIIYMQDRPVGVMIRKNMIVSPGNFIDVNGSADTVRKMWNDRYPWPLKLAHQLSTRHAETGGRVSEYSIESAHELH
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA (By similarity).
What are the official names of this protein?
Bifunctional methyltransferase/endonuclease.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBL4B_MONDO
Sequence: MWLTVKLLLGRRCLLQVSENEKVFMLKRLVSKQLHVPEKQQRLLFRGQVLADNKRLSDYCIGPNSTLNVIIRPLEKTSPETPSQPRSQSLWPQLNQILLKHFSPQDAENVLRRLREDHRKSLQRMNLDDLERISKVLVPEGKHSGATGSTRESKGDMEPRRNMKCNLAHKDGFKREKSPGK
What are the official names of this protein?
Ubiquitin-like protein 4B.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMYD5_HUMAN
Sequence: MAASMCDVFSFCVGVAGRARVSVEVRFVSSAKGKGLFATQLIRKGETIFVERPLVAAQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLPHPELCTVRKDLHQNCPHCQVMYCSAECRLAATEQYHQVLCPGPSQDDPLHPLNKLQEAWRSIHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKGQLELLRRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDTLELKPQDREQLDAFIDQLYKDIEAATGEFLNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIKPGEEICISYLDCCQRERSRHSRHKILRENYLFVCSCPKCLAEADEPNVTSEEEEEEEEEEEGEPEDAELGDEMTDV
What is the function of this protein?
Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3) which represents a specific tag for epigenetic transcriptional repression (By similarity).  In association with the NCoR corepressor complex, is involved in the repression of toll-like receptor 4 (TLR4)-target inflammatory genes in macrophages by catalyzing the formation of H4K20me3 at the gene promoters (By similarity).  Plays an important role in embryonic stem (ES) cell self-renewal and differentiation (By similarity).  Promotes ES cell maintenance by silencing differentiation genes through deposition of H4K20me3 marks (By similarity).  Maintains genome stability of ES cells during differentiation through regulation of heterochromatin formation and repression of endogenous repetitive DNA elements by depositing H4K20me3 marks (PubMed:28951459).
What are the official names of this protein?
Histone-lysine N-trimethyltransferase SMYD5, Protein NN8-4AG, Retinoic acid-induced protein 15, SET and MYND domain-containing protein 5, [histone H4]-lysine20 N-trimethyltransferase SMYD5.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily.
Protein: SSRB_CAEEL
Sequence: MKFSLFALLFVVVSCVDVGTQTRDAFILAHKQPLSTYAVENMDFVLEYGLYNVGDKPAQKVTIDDRHSFPTNSFDIVKGLLFVHFEQIPAGSNVTHSVVIRPRAFGFFNYTAAQVTYYTDNENHHVTLTNTPGEGYIYRQREYDRRFAPKYTYFLVFFLIVAPTTLGSFLLFQQSKARFPNVIKKKST
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit beta.
What is the protein family that this protein belongs to?
Belongs to the TRAP-beta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: RAB21_BOVIN
Sequence: MAAAGGGGAAAGRTYSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKVDLEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPGAARRGVQIIDDEPQAQSVGGGCCSSG
What is the function of this protein?
Small GTPase involved in membrane trafficking control (By similarity).  Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity).  As a result, may regulate cell adhesion and migration (By similarity).  During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis (By similarity).  Involved in neurite growth (By similarity).  Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion (By similarity).  Modulates protein levels of the cargo receptors TMED2 and TMED10, and required for appropriate Golgi localization of TMED10 (By similarity).
What are the official names of this protein?
Ras-related protein Rab-21.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Lipid-anchor. Golgi apparatus, trans-Golgi network. Golgi apparatus membrane. Early endosome membrane. Cytoplasmic vesicle membrane. Cleavage furrow. Cell projection, neuron projection. Note=Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm. During mitosis, in mid-telophase, localized in the ingressing cleavage furrow. In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (By similarity).
Protein: BTUF_YERPS
Sequence: MMPLGLFPLPRAAVVLLISLLTLPAQAAERVISLSPSTTELAYAAGLGDKLVAVSAYSDYPESAKKLEHVASWQGINVERILALKPDLILAWRGGNPQRPLDQLAALGIPIFYSDPTHIDQIASDLDKLAQYSPHPEQAHQAAEQFRQHVNTLRDRYARSQPKRTFLQFGTQPLFTSSGHTLQSEVVSLCGGENIFADSRVPWPQVSREQVMTRKPQVIVVSGTQSQVDNVSAFWLPQLVVPVIALNEDWFNRASPRILLAAQQLCQQMASIPTPVAESH
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Binds vitamin B12 and delivers it to the periplasmic surface of BtuC.
What are the official names of this protein?
Vitamin B12-binding protein.
What is the protein family that this protein belongs to?
Belongs to the BtuF family.
What are the subcellular locations of this protein?
Periplasm.
Protein: KAD6_RABIT
Sequence: MRLPNILLTGTPGVGKTTLGKELASRSGLKYVNVGDLAREGELYDGFDEEYNCPILDEDRVIDELDTQMRDGGVIVDYHGCDFFPERWFHIVFVLRTETSVLYKRLETRGYSEKKLNDNIQCEIFQVLYEEAMESYKEEIVHQLPSNKPEELEENISQILKWIEQWIKDHNS
What is the function of this protein?
Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.  May have a role in nuclear energy homeostasis.  Has also ATPase activity.  May be involved in regulation of Cajal body (CB) formation.
What are the official names of this protein?
Adenylate kinase isoenzyme 6, AK6, Coilin-interacting nuclear ATPase protein, Dual activity adenylate kinase/ATPase, AK/ATPase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. AK6 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.
Protein: DEOC_STAS1
Sequence: MNYAKYIDHTLLKPESTRNQIDKIIEEAKAFNFKSICINPTHVKYAAEQLKGSDVLVCTVIGFPLGASTTETKIFETKDAINKGASEVDMVINIGALKDGRFEDVQKDIEGVVGAANGKTVKVIIETCLLTDEEKVKASELSKVAGADFVKTSTGFAGGGATPEDVKLMKDTVGDDLEVKASGGVRNLEDFNHMLEAGATRIGASAGVEIVQGLESDSDY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_CORGL
Sequence: MPRSLKKGPFVDEHLLNKVDAQNEKGTKQVIKTWSRRSTILPDFIGHTFAVHDGRKHVPVFVDDAMVGHKLGEFAPTKTFKGHVKDDKKGRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PAL_HAEIN
Sequence: MNKFVKSLLVAGSVAALAACSSSNNDAAGNGAAQTFGGYSVADLQQRYNTVYFGFDKYDITGEYVQILDAHAAYLNATPAAKVLVEGNTDERGTPEYNIALGQRRADAVKGYLAGKGVDAGKLGTVSYGEEKPAVLGHDEAAYSKNRRAVLAY
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Peptidoglycan-associated lipoprotein, PAL, 15 kDa peptidoglycan-associated lipoprotein, PC protein, Outer membrane protein P6, OMP P6.
What is the protein family that this protein belongs to?
Belongs to the Pal lipoprotein family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y2087_METPB
Sequence: MTQCPFTPCADGLILAVRLTPRAGRTGLDGVRTEPDGRPILCLRVAAPPVEGAANAALTAFVAKSLGLRKSEVTLVSGETARTKRLHLSGDPQALAARATAWFGGDGPGS
What are the official names of this protein?
UPF0235 protein Mpop_2087.
What is the protein family that this protein belongs to?
Belongs to the UPF0235 family.
Protein: FKBP_CRYNB
Sequence: MGVTVENISAGDGKTFPQPGDSVTIHYVGTLLDGSKFDSSRDRGTPFVCRIGQGQVIRGWDEGVPQLSIGQKANLICTPDYAYGARGFPPVIPPNSTLKFEVELLKIN
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
FK506-binding protein 1, FKBP, Peptidyl-prolyl cis-trans isomerase, PPIase, Rapamycin-binding protein.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSAD_FRAT1
Sequence: MIVLGIESSCDETGLAIYDYSKKKLIADELYSQVKLHKKYGGVVPELASREHIAKLNLLAKKIFKETGLSFEDIDCIAYTAMPGLVGALMVGATFAKTLGLIHNIDTIAVHHLEGHLLSPLLDHNSNIEYPFVALLVSGGHTQLFEVKEFGEYSLLGESIDDAAGEAFDKTTKLLGMGYPGGVEVANLADQATDKSKYILPRPMKNKPNLDFSFSGLKTAVLNTWYDEQDQSLENKANLCYAFQDAAIDVLVSKCAKALQKTKNTRLVISGGVSANKLLRHQLDLLAKNRGYQIFFPPMKYCTDNGAMIALAGAYRYVNGFKDSNLEINVKARSPL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.