PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_NOSS1
Sequence: MAADFAASVILDTALSVSGLTDYLRLLLEHDEQLRQVWVVGEVSSTNHHRSGLFFTLQDPDGSAAIKCVVWSSQVPKLAQLPVAGEQLIVLGSIRLYPQRGEYQLSVWQAVPAGVGLQALRYQQLKNRLLAEGLFDPQRKRSLPIHPQTIAVVTSPTAAAWGDIQKTLKHRYPGLHVLFSPATVQGEQAPESIVKAIARVEKDGRAEVLILSRGGGAVEELACFNDERVVRAVAECSIPVVTGIGHQRDESLVDLVADVCVHTPTAAAEKVVPSLAELSNQHRQRIIALHQVLLHTQTSAENQLQTLRNRLQNLRLDRHLQQEAQKLNWQRQRLLQLTMGRSQQAKQHLELLRQKLISLDPKSVLQRGYAVVRQENGAIARSADELAVGNELFIQLAQGEVKAKVIEVEQRQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA_RHIME
Sequence: MIQKNWQELIKPNKVEFASSGRTKATLVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIPGVREDVTDIVLNIKEIAIKMDGDDAKRMVVRKQGPGVVTAGDIQTVGDIEILNPNHVICTLDEGAEIRMEFTVNNGKGYVPADRNRSEDAPIGLIPVDSLYSPVKKVSYKVENTREGQVLDYDKLTMSIETDGSVTGEDAIAFAARILQDQLSVFVNFDEPQKETEEEAVTELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEVPSWPPENIEDLAKRYEDQY
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: MINE_PSEP1
Sequence: MNLFDFFRGRQKQTSASVAKERLQIIVAHERGQRSEPDYLPALQKELLEVIRKYVNIGNDDVHIELENQGSCSILELNITLPDR
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: CC1_BUNCI
Sequence: GLRDFNVAVRASNGKYWTRRPESGTLV
What are the official names of this protein?
Cationic protein C1.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: SPT4_GIBZE
Sequence: MSSSNYVTTGQARNLRACMICSIVMTSQRFQNEGCPNCEEFLHLQHSPDQIESCTSQVFEGVITLANPTKSWIAKYQRLDSYVPGMYAIKVSGQLPDDVRSTLEDEYRIQYIPRDGTEVENDA
What is the function of this protein?
The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing.  This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4, Chromatin elongation factor SPT4.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Centromere and heterochromatin.
Protein: PVHB_TALVA
Sequence: MGNKMTKRISHFNIENAIIPGEVSASAHVPGENNIFPKYSSNINDRTWEIWCCEGINHEGAGVMFGFQRAAFNKKMGGGWRVQIIAVWPDGKNWYKALALPESIFEESMASGDITSVWKTADNSTNVSFTYHKVDNKIDVVVCIPGVATGKASFQGQPGDSGLSTSPSLGPYVSYMRPVGRADMTSDMIFHFPDDGTTRQISFSDGHGGFDRYWGEKLWLSIQSESYFMRAFLGPYVIQIIRLVSTEELGKQQWPIARLFHQGKLVCAPQRCGSPDEQGISQDTLVMSKVHDSDTGALSAEFHDKSTGYDLTFVEAGNARRRWTFTVRHQTKIWSLPIGPKGGNSGFVEHVCGGLAGETCEGLGVSGQIVY
What is the function of this protein?
Diels-Alderase; part of the gene cluster that mediates the biosynthesis of varicidin A, an antifungal natural product containing a cis-octahydrodecalin core (PubMed:30609896).  The PKS module of pvhA together with the enoylreductase pvhC catalyze the formation of the polyketide unit which is then conjugated to L-isoleucine by the condensation domain of the NRPS module (PubMed:30609896).  Activity of the Dieckmann cyclase domain (RED) of pvhA results in release of an acyclic tetramate (PubMed:30609896).  The cytochrome P450 monooxygenase pvhE then catalyzes the oxidation of the C21 methyl group to a to carboxylate group (PubMed:30609896).  The methyltransferase pvhD then further methylates the pvhE product (PubMed:30609896).  The Diels-Alderase pvhB is able to catalyzes Diels-Alder cycloaddition using both pvhE and pvhD products as substrates to form the decalin ring, yielding varicidin B and A, respectively (PubMed:30609896).
What are the official names of this protein?
Diels-Alderase pvhB, Varicidin biosynthesis cluster protein B.
What is the protein family that this protein belongs to?
Belongs to the Diels-Alderase family.
Protein: PSF2_ASPFU
Sequence: MAFPLPRGITPPEIAFLAEMEMVTILPRQRLEGLELLGGQVEPLLPPRRASLPLWLALLLKRQRRANILPPAWLHPEPLSLILEIETQHHEYENAFSPPPPLPGQPSVRDRNRGQRPIARARHTPDGQRYFPSPPFLPQNIAQDNAHPSEPPSLPYHWLEVGNMLLDAASDDLVDPDQIRRLLKELREVRMAKIRSGVDVLDAAATGGGGVALTGVGAMEIGESRGFVTGVVDGLRKIGASKEQARREQMAEEMANGGYDATQDDEDEMEF
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein psf2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: END4_SALHS
Sequence: MKYIGAHVSAAGGLANAPARAAEIGATAFALFTKNQRQWRAAPLTPQVIDDFKIACEKYHFSAAQILPHDSYLINLGHPVSEALEKSRDAFLDEMQRCEQLGLTLLNFHPGSHLMQIAQEDCLARIAESINIALAQTEGVTAVIENTAGQGSNLGFEFEQLAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPEACEKTFAEFGKIVGFQYLRGMHLNDAKSAFGSRVDRHHSLGEGNIGHDAFRWIMQDARFDGIPLILETINPDIWAEEIAWLKAQQIAEAVA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: MUTL_STRA1
Sequence: MSKIIELPDILANQIAAGEVVERPSSVVKELVENAIDAGSSQITIEVEESGLKKIQITDNGEGMTSEDAVLSLRRHATSKIKSQSDLFRIRTLGFRGEALPSIASISLMTIKTATEQGKQGTLLVAKGGNIEKQEVVSSPRGTKILVENLFFNTPARLKYMKSLQSELAHIIDIVNRLSLAHPEVAFTLINDGKEMTKTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEISGYVSLPELTRANRNYITLLINGRYIKNFLLNRSILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKERELMSLISSAISESLKQYDLIPDALENLAKTSTRSVDKPIQTSFSLKQPGLYYDRTKNDFFIDADTVSEPIANFTNLDKSDGSVDNDVKNSVNQGATQSPNIKYASRDQADSENFIHSQDYLSSKQSLNKLVEKLDSEESSTFPELEFFGQMHGTYLFAQGNGGLYIIDQHAAQERVKYEYYREKIGEVDNSLQQLLVPFLFEFSSSDFLQLQEKMSLLQDVGIFLEPYGNNTFILREHPIWMKEEEVESGVYEMCDMLLLTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARHLLDQLAQCKNPYNCPHGRPVLVNFTKADMEKMFKRIQENHTSLRDLGKY
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PEN6_ARATH
Sequence: MWRLKIGAKGGDETHLFTTNNYTGRQTWEFDADACSPEELAEVDEARQNFSINRSRFKISADLLWRMQFLREKKFEQKIPRVEIGDAENITYKDAKTALRRGILYFKALQAEDGHWPAENSGCLFFEAPFVICLYITGHLEKILTLEHRKELLRYMYNHQNEDGGWGIHVEGQSAMFCTVINYICLRILGVEADLDDIKGSGCARARKWILDHGGATYTPLIGKAWLSILGVYDWSGCKPIPPEVWMLPTFSPFNGGTLWIYFRDIFMGVSYLYGKKFVATPTPLILQLREELYPQPYDKILWSQARNQCAKEDLYYPQSFLQEMFWKCVHILSENILNRWPCNKLIRQKALRTTMELLHYQDEASRYFTGGCVPKPFHMLACWVEDPDGDYFKKHLARVPDYIWIGEDGLKIQSFGSQLWDTAFSLQVMLAYQDVDDDDDEIRSTLIKGYSFLNKSQLTQNPPGDHRKMLKDIAKGGWTFSDQDQGWPVSDCTAESLECCLVFGSMPSELIGEKMDVERLYDAVNLLLYFQSKNGGITVWEAARGRTWLEWLSPVEFMEDTIVEHEYVECTGSAIVALARFLKEFPEHRREEVEKFIKNAVKYIESFQMPDGSWYGNWGVCFMYGTFFAVRGLVAAGKTYQNCEPIRKAVQFILETQNVEGGWGESYLSCPNKKYTLLEGNRTNVVNTGQALMVLIMGGQMERDPLPVHRAAKVLINSQLDNGDFPQEEIMGVFKMNVMVHYATYRNIFTLWALTYYTKALRVPLC
What is the function of this protein?
Multifunctional enzyme that converts oxidosqualene to lupeol, bauerenol, alpha-amyrin, taraxasterol, psi-taraxasterol, multiflorenol, alpha-seco-amyrin and beta-seco-amyrin.
What are the official names of this protein?
Seco-amyrin synthase, Alpha-seco-amyrin synthase, Beta-seco-amyrin synthase, Pentacyclic triterpene synthase 6, AtPEN6.
What is the protein family that this protein belongs to?
Belongs to the terpene cyclase/mutase family.
Protein: RF3_ECO55
Sequence: MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APGM_METM7
Sequence: MKAVIFIMDGLGDRPNKDGNTPLKEAKTPIMDKMAKDGICGLMNAVDVGVRPGSDTAHLAILGYDPYTTYTGRGPFEACGVGVTVKPGDIAFRCNFSSVDENFIVTDRRAGRIENTSELEKELDGLKIDDVEIIFKESGGYRAALVLRGPGLSDRISDADPKKEGKRVKEIHPLDDSKEAKKTAEIVNRLLKIAYEKLDKHPVNEERRKQNLPVANMIVPRGVGQVPEIMPFTEKTGLKGACIAGTGLIKGIAKMVGLDVIDVEGCDGTPNSDLMAKACAIVETLKNYDFILVNVKGADEAGHDGNYELKKEIIERIDEMLDYITKNISKDEVYFVISGDHSTPIEEMDHSADPLPIVIWGKSVRVDDVEKFDEFSTHKGGLNWIKGTNIMPILMDLMSIAKKYGA
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, aPGAM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
Protein: TRUD_PYRAR
Sequence: MREAPPFDKALGMYYYVTDTCPSGGVIKKSPEDFVVEEVLADGTVVAVGGVELRPRVGGWTWIHVVKRNVDTIRLMIRLAKALGVSPREVSVGGIKDTRAVASHIISVRGAVKGLPEIPGVKFLGMWSMDRPMSPSEIYGNRFTIVLRDVERVDCAVEALEALKSAAVPNYYGYQRFGTIRPVSHLLGRALLRKSPEEFFDAMFCKIFEHESAAAKKARELACRGEYQKALETFPRRFVEERAFLRRLAQGYDMWNAIMGIPLQILRIYVEAAQSYLFNRFLSARLELGPLDKPLEGDLVEVGGQVAYYAEGLGGDVVLPVAGAGVRMPRGKVGEALLKVMKEEGVDPAAFLKMPRGLKAYGSYRRARLEVGDFSYAVRGRDVELRFVLPRGSYATVLLREAVKPAEPYRHGF
What is the function of this protein?
Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.
What are the official names of this protein?
Probable tRNA pseudouridine synthase D, tRNA pseudouridine(13) synthase, tRNA pseudouridylate synthase D, tRNA-uridine isomerase D.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruD family.
Protein: RL36_WOLTR
Sequence: MKVKGSLKSHRNRDKNCKVVKRGGRIYIINEIKPRCKTRQGS
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: VSP2_BOTJA
Sequence: MVLIRVLANLLILQLSYAQKASELIIGGRPCDINEHRSLALVKYGNFQCSGTLINQEWVLSAAHCDGEKMKIHLGVHSKKVPNKDKQTRVAKEKFFCLSSKNYTKWDKDIMLIRLDSPVKNSAHIAPISLPSSPPIVGSVCRIMGWGTISTSKVILSDVPHCANINLLNYTVCRAAYPELPATSRTLCAGILQGGKDTCVGDSGGPLICNGQFQGIVSWGSDVCGYVLEPALYTKVSDYTEWINSIIAGNTTATCPP
What is the function of this protein?
Thrombin-like snake venom serine protease that clots fibrinogen (FGA) by releasing only fibrinopeptide A.  Also releases bradykinin from bovine low-molecular-mass kininogen (KNG).
What are the official names of this protein?
Thrombin-like enzyme KN-BJ 2, SVTLE, Kinin-releasing and fibrinogen-clotting serine protease 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS9_METMA
Sequence: MVKVINSSGKHKTATARATVMKGTGKVRINKIPLELYTPELAMMKISEPLLIAGKDVVSGLDINVDVRGGGIVGQANAVRTAVARGIVEWTNDTTIRDNFAAYDRNLLVSDSRQKEAKNFGGPGARSKYQKSYR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: UTP11_RAT
Sequence: MAAAFRKAVKSRQREYRERSQPGFRKHLGLLEKKKDYKLRADDYRKKQEYLKALRKKALEKNPDEFYYKMTRVKLQDGVHIIKETKEEVTPEQLKLMRTQDVKYIEMKRVAEAKKIERLKSELHLLDFQGKQQNRHVFFFDTKKEVEQFDVAAHLQTAPELVDRVFNRPRIETLQKEKVKGVTNQTGLKRIAKERQKQYNCLTQRIEREKKLFVIAQKIQTRKDLMDKTQKVKVKKETVNSPAIYKFQSRRKR
What is the function of this protein?
Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.  Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
Probable U3 small nucleolar RNA-associated protein 11, U3 snoRNA-associated protein 11, UTP11-like protein.
What is the protein family that this protein belongs to?
Belongs to the UTP11 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RAB6D_HUMAN
Sequence: MSAGGDFGNPLRKFKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSLIPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTEGGSDVIITLVGNKTDLADKRQVSIEEGERKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDIKLEKPQEQTVSEGGCSCYSPMSSSTLPQKPPYSFIDCSVNIGLNLFPSLITFCNSSLLPVSWR
What are the official names of this protein?
Ras-related protein Rab-6D, Rab6-like protein WTH3DI.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
Protein: MINC_CALS4
Sequence: MVREPVKIQGTKEGLVIVVDEDVDIEVLKERIVDRIEKSLKFFEGATLNVRVKNSKFKDEELEDLKDFILKNYGVEIFIKKFQEKHIKNVTDDEIFNGLEEGITKFHRGTVRSGQVVKYYGNLVIIGDVNPGGLVQAAGNIVVTGTLRGIAHAGFTGNKEAFIVASSLKAMQLRIANIISRAPDKEEEVEYPEIAVVRKNKIIVRPLYHLSDLW
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: ISPE_ECO57
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGANLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PGLB_CAMLR
Sequence: MKLQQNFTDNNSIKYTCILILIAFAFSVLCRLYWVAWASEFYEFFFNDQLMITTNDGYAFAEGARDMIAGFHQPNDLSYFGSSLSTLTYWLYSILPFSFESIILYMSAFFASLIVVPIILIAREYKLTTYGFIAALLGSIANSYYNRTMSGYYDTDMLVLVLPMLILLTFIRLTINKDIFTLLLSPVFIMIYLWWYPSSYSLNFAMIGLFGLYTLVFHRKEKIFYLTIALMIIALSMLAWQYKLALIVLLFAIFAFKEEKINFYMIWALIFISILILHLSGGLDPVLYQLKFYVFKASDVQNLKDAAFMYFNVNETIMEVNTIDPEVFMQRISSSVLVFILSFIGFILLCKDHKSMLLALPMLALGFMALRAGLRFTIYAVPVMALGFGYFLYAFFNFLEKKQIKLSLRNKNILLILIAFFSISPALMHIYYYKSSTVFTSYEASILNDLKNKAQREDYVVAWWDYGYPIRYYSDVKTLIDGGKHLGKDNFFSSFVLSKEQIPAANMARLSVEYTEKSFKENYPDVLKAMVKDYNKTSAKDFLESLNDKDFKFDTNKTRDVYIYMPYRMLRIMPVVAQFANTNPDNGEQEKSLFFSQANAIAQDKTTGSVMLDNGVEIINDFRALKVEGASIPLKAFVDIESITNGKFYYNEIDSKAQIYLLFLREYKSFVILDESLYNSSYIQMFLLNQYDQDLFEQITNDTRAKIYRLKR
What is the function of this protein?
Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (GalNAc(2)GlcGalNAc(3)Bac(NAc)(2) in eubacteria, where Bac(NAc)(2) is di-N-acetyl bacillosamine) from the lipid carrier undecaprenol-pyrophosphate to an asparagine residue within an Asp/Glu-Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation.
What are the official names of this protein?
Undecaprenyl-diphosphooligosaccharide--protein glycotransferase, Protein glycosylation B.
What is the protein family that this protein belongs to?
Belongs to the STT3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MOAC_GLAP5
Sequence: MNTFTHINQNGEANMVDVSAKQDTVREARAEAFVTMNPETLQMIISGNHHKGDVFATARIAGIQAAKRTWELIPLCHPLLLSKVEVQLEALPEKNQVRIESLCKLSGKTGVEMEALTAASAAALTIYDMCKAVQKDMVIEQVRLLSKSGGKSGDFVAKS
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: TRIP4_MOUSE
Sequence: MAVAGAAYREPLVHWCTQQLQKTFALDVSEEIIQYVLSIENAEEIREYVTDLLQGNEGKKGQFIEDLITKWQKNDQEFISDSFQQCLRKDEILDGQRSVDQLKRSRRKGRNKQEVPAFPEPDVAVEVKTPLDLAKAQESNNSVKKKTRFVNLYTREGQDKLAVLLPGRHPCDCLGQKHKLINNCLVCGRIVCEQEGSGPCLFCGSLVCTNEEQDILQRDSNKSQKLLKKLMSGAETSGKVDVSTKDLLPHQESRMKSGLEKAIKHKEKLLEFDRTSIRRTQVIDDESDYFASDSNQWLSKVEREMLQKREEELRELRHASRLSKKVTIDFAGRKILEDENPLAEYHSRLDETIQAIASGTLNQSLVTLDRSCEEPLGVLVNPNMYQASPQWVDNTGSTPQKKTSLSAGPRLEPSLHQHQLRIQDQEFQEGFDGGWCLSMHQPWASLLVRGIKRVEGRSWYTPHRGRLWIAATGKRPSPQEVSELQATYRLLRGKDVEFPNDYPSGCLLGCVDLIDCLSQKQFQEQFPDISQESDSSFVFICKNPQEMVVKFPIKGNPKIWKLDSKIHQGAKKGLMKQNKAV
What is the function of this protein?
Transcription coactivator which associates with nuclear receptors, transcriptional coactivators including EP300, CREBBP and NCOA1, and basal transcription factors like TBP and TFIIA to facilitate nuclear receptors-mediated transcription.  May thereby play an important role in establishing distinct coactivator complexes under different cellular conditions.  Plays a role in thyroid hormone receptor and estrogen receptor transactivation (By similarity).  Also involved in androgen receptor transactivation (PubMed:12077347).  Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1.  Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B.  May play a role in the development of neuromuscular junction (By similarity).  May play a role in late myogenic differentiation (PubMed:27008887).  Also functions as part of the RQC trigger (RQT) complex that activates the ribosome quality control (RQC) pathway, a pathway that degrades nascent peptide chains during problematic translation (By similarity).
What are the official names of this protein?
Activating signal cointegrator 1, ASC-1, Thyroid receptor-interacting protein 4, TR-interacting protein 4, TRIP-4.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Cytoplasmic under conditions of serum deprivation. Colocalizes with NEK6 in the centrosome.
Protein: PSF2_XENLA
Sequence: MDASEVEFLAEKEQVTVIPNFSLDKVYLIGGDLGPFNPSLPVEVPLWLAINLKQRQKCRIVPPEWMDVEKLEAIRDQERREETFTPMPSPYYMELTKLLLNHAADNIPKADEIRTLVKDTWDTRIAKLRLSADSFVKGQEAHAKLDNLTLMEINTIGTFFTESLNHMYKLRTSLQNPEEGQSQDY
What is the function of this protein?
Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks.  GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
What are the official names of this protein?
DNA replication complex GINS protein PSF2, GINS complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromatin.
Protein: ATPG_POLAQ
Sequence: MASTKEIRSKIKSVQNTRKITKAMEMVAASKMRRAQERMRNARPYAEKIREIVANLSKANPEFRPAYMEAREVKKVGTILVTTDKGLCGGLNTNVLRFITNQVRDLQEKNIEIVYTAIGSKGLQFLNRSKAKLISQTIQIGDTPHMDVLIGAIIAQLEAFERGEIDAVYLAYNRFVNAMKQEPVLEKLLPLEPAALVPEDKAGNSWDYIYEPDAESILNGLLKRYVEAMIYQAVTENMASEQSARMVSMKAASDNAKNVIGELQLEYNKTRQAAITKELSEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PEPX_STRP8
Sequence: MRYNQFSYIPTSLERAAEELKELGFDLDLQKTAKANLESFLRKLFFHYPDSDYPLSHLIAKNDMDALSFFQSEQELSKEVFDLLALQVLGFIPGVDFTEADAFLDKLAFPIHFDETEIIKHIHHLLATRCKSGMTLIDDLVSQGMLTMDNDYHFFNGKSLATFDTSQLIREVVYVEAPLDTDQDGQLDLIKVNIIRPQSQKPLPTLMTPSPYHQGINEVANDKKLYRMEKELVVKKRRQITVEDRDFIPLETQPCKLPIGQNLESFSYINSYSLNDYFLARGFANIYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNRRATAYTSHSKTHQVRADWANGLVCTTGKSYLGTMSTGLATTGVDGLAMIIAESAISSWYNYYRENGLVCSPGGYPGEDLDVLTELTYSRNLLAGDYLRHNDRYQELLNQQSQALDRQSGDYNQFWHDRNYLKNAHQIKCDVVYTHGLQDWNVKPRQVYEIFNALPSTINKHLFLHQGEHVYMHNWQSIDFRESMNALLCQKLLGLANDFSLPEMIWQDNTCPQNWQERKVFGTSTIKELDLGQELLLIDNHYGEDEFKAYGKDFRAFKAALFEGKANQALVDILLEEDLPINGEIVLQLKVKSSENKGLLSAQILDYGKKKRLGDLPIALTQSSIDNGQNFSRESLKELPFREDSYRVISKGFMNLQNRNNLSSIETIPNNKWMTVRLPLQPTIYHLEKGDTLRVILYTTDFEHTVRDNSNYALTIDLSQSQLIVPIASN
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FB190_ARATH
Sequence: MERQKKKDMDFLTEDLWEIILARLPLKSIITTPKLVCKVWKSIIESRCFRDLFQSLHQNSHHSSWSLMCRGCETEIMSHYGSDNWNLNHSLGYYISSFLTDKFENYNEARVVSYTDVGLILVHRVSSQSFYVANPVSRQCVEILPSQKLDCFWILGIATRVENGVVLGYKVVLLKPNFTFLIYSSETGLWSLNSDTFPFSYISQEFNNPISLNGSLYWLAHGSEYQDFIVSIDFYVVDSRSDRCRATPFPDLDKVPKFRRTCTTSQGCLMYMNIFSIPKVDGNLEDKLCVWRLESWQWRLVFEISLDSIKTGFDYIPLGTDPFDAKTVYLWSRKCLLSINLHNGDIVLHKDVEHSSAGRILNSVDCPRDMTYILESNFASFVLPQWMHPFPSTVRSV
What are the official names of this protein?
F-box protein At3g28330.