PharMolix/UniProtQA huggingface dataset:
Protein: BTUD_VIBC3
Sequence: MIRVNSLQVDSRLLPLSLQANAGEVWHVIGPNGCGKSTLLAALAGMIPFSGSVQVGGLNVSQASLSELARHRAYLAQNDKPSFQLHVFQYLALSVPANVALERSEVASEIDQISRLLNIDDKLHRSIHQLSGGEWQRVRLAGSCLQVSPVLNPSARLLIWDEPAAPLDIAQESLLYRLIERMAGQGLTVIMANHDLNRTLRHADQVLLLSRGVLYRAGSAKEVLTQEVLQSVFGTSIRRVELEGHPHLLFD
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Vitamin B12 import ATP-binding protein BtuD, Vitamin B12-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Vitamin B12 importer (TC 3.A.1.13.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUOD_GEOTN
Sequence: MLRTEEMILNVGPQHPSTHGVFRLILKIDGEIIQEATPVIGYLHRGTEKIAEGLQYTQIIPYTDRMDYLSAMTNNYVLCHAVETMMGIEVPERAEYLRVLAMELGRIASHLVWWGTYLLDLGATSPFLYAFREREMIINLLNELSGARLTFNYMRIGGVKWDAPDGWIDKVKQFVPYMREKLAGYHDLVTGNEIFRERVTGVGRYTKEEAISYSLSGVNLRSTGVKWDLRKDEPYSVYDRFDFDVPVREGGDCLARYECRMAEIEQSLRIIEQACEQFPADGPIMGKLPRIIKAPPGETFVRIEAPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENLANVIAILGSIDIVLGEVDG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: GMHA_MYCTA
Sequence: MCTARTAEEIFVETIAVKTRILNDRVLLEAARAIGDRLIAGYRAGARVFMCGNGGSAADAQHFAAELTGHLIFDRPPLGAEALHANSSHLTAVANDYDYDTVFARALEGSARPGDTLFAISTSGNSMSVLRAAKTARELGVTVVAMTGESGGQLAEFADFLINVPSRDTGRIQESHIVFIHAISEHVEHALFAPRQ
What is the function of this protein?
Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
What are the official names of this protein?
Phosphoheptose isomerase, Sedoheptulose 7-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GmhA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DABA_STAEQ
Sequence: MLQSDINELVNQAKRVITPLSPISTFAARNPWEGLEDASFDQVARWLKSVRDVDIYPNASTIHRAISNKEIDLKVFEERLDENRAHYNNRSLSDSDINTYIQRAKNLKTIEEGYFNTKDNEKLEKWVQTNFKDYKKKEDVIAQSASVFTKEGTRLIDILNAHMIKWSKLYVDDFQSSWTMPKREKGFYHAWQRLVKHDPLFTKKQRLTLAHLPNQATEAIEYAFQELGVKEEHRQSYIESHLLSLPGWAGIMYHRSQTQSNDAYLLTDYVAIRLSIEMVLLNDHHTTLLKKSIYLQKKLEQIRYLLFNIQMNVEQWLNLSSKKQQAYIELGTRFSPFYFKKLWLDAWEETHERRLVDEIYRVPTEDTDQAKAKVQLAFCIDVRSEPFRRHLESEGPFETIGIAGFFGLPIQKEVLDEQFAHPSLPVMVEPAYRIKEYADQHEMKIYNQQQHTLTSMFYNFKLMKNNVLPSLLLPELSGPFLSIATIANTIFPKKAKRIVHRFSQKWLRKPTGKLTIQREQDAYSKLPIGFTLEEQIQFSKKALQLMDLTDDFAPLIVLCGHGSESHNNPYHASLECGACGGASSGFNAKLLAVMCNQENVRRGLLMEGIDIPRHTVFIAAEHQTSVDELEYIYVPPLTTEAQNAFDELKHVMPKVCYKANLERLASLPNINNTDHNPNAEAHRHASDWSEVRPEWGLARNAEFIIGKRQITQNSNLEGRAFLHNYDWTKDEDGEILNTIISGPALVAQWINLQYYASTVAPHYYGSGSKTTQTVTSGVGVMQGNASDLMYGLPWQSVMMNDKEAYHAPIRLLIVIQAPDAYIQRLLKHHNHFRQKVDHQWIRLASIDENNSWKDW
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TMPC_TREPA
Sequence: MREKWVRAFAGVFCAMLLIGCSKSDRPQMGNAGGAEGGDFVVGMVTDSGDIDDKSFNQQVWEGISRFAQENNAKCKYVTASTDAEYVPSLSAFADENMGLVVACGSFLVEAVIETSARFPKQKFLVIDAVVQDRDNVVSAVFGQNEGSFLVGVAAALKAKEAGKSAVGFIVGMELGMMPLFEAGFEAGVKAVDPDIQVVVEVANTFSDPQKGQALAAKLYDSGVNVIFQVAGGTGNGVIKEARDRRLNGQDVWVIGVDRDQYMDGVYDGSKSVVLTSMVKRADVAAERISKMAYDGSFPGGQSIMFGLEDKAVGIPEENPNLSSAVMEKIRSFEEKIVSKEIVVPVRSARMMN
What is the function of this protein?
Binds purine nucleosides and may play a role in purine nucleoside uptake.  May be part of an ABC-type nucleoside uptake system.  Has highest affinity for guanosine, followed by inosine and adenosine.  Has very low affinity for cytidine and does not bind thymidine.
What are the official names of this protein?
Membrane lipoprotein TmpC, Membrane protein C, 35 kDa antigen, Lipoprotein TpN35, Purine nucleoside receptor A, PnrA.
What is the protein family that this protein belongs to?
Belongs to the BMP lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RTN1A_XENLA
Sequence: MQASADSTRMECLWSNWKCQAIDLLYWRDIKQTGIVFGSVLLMLFSLIQFSVVSVMAYLALAALSATISFRIYKSVLQAVQKTDEGHPFKSYLDMEISLSQEQIQKYTDCLQVYTNSIAKELRRLFLVQDLVDSLKFAVLMWLLTYVGALFNGLTLLIMAVVSMFSLPVVYDKYQAQIDQYLGLVRTNMNTIMTKIQAKIPGTKQKE
What is the function of this protein?
Inhibits amyloid precursor protein processing, probably by blocking BACE1 activity.
What are the official names of this protein?
Reticulon-1-A, RTN1.1, xRTN1, XRTN1-C.1.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus. Note=Mainly localized to the endoplasmic reticulum with some expression in the nucleus and polysome fractions.
Protein: PUR5_SINFN
Sequence: MSQSGKNGLTYSDAGVDIDAGNLMVEKIKPHVRSTRRPGADGEIGGFGGLFDLKAAGFTDPVLVAANDGVGTKLKIAIDANKHDTVGIDLVAMCVNDLVVQGAEPLFFLDYFATGKLDPDQGAAIVAGIAAGCREAGCALIGGETAEMPGMYSGGDYDLAGFAVGAAERGQLLPAGGIAEGDVILGLASSGVHSNGYSLVRKIVSLSGLAWDAPAPFGEGTLADLLMTPTRIYVKPLLKAIRATGAIKALAHITGGGFPENIPRVLPKHLAAEIDLDAIKPPAVFSWLAKTGGVAANEMLRTFNCGVGMIAVVPAEEADRVAAVLAGEGETVFRLGRMVARQDGAPGTIYKGSLAL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NNRE_SCHPO
Sequence: MSISCLSASAAKALDAELMSAGAFSIDQLMELAGLSVSQAVYREYPPSQYSQVLICCGPGNNGGDGLVAARHLWQYGYKPTVYYPKPSSPELYKRLCKQLDDLDIPVVKSHDSNHFSQLLRDSKLVVDSIFGFSFKGPVRDPFGSILAAIVESKIKVLSVDAPSSWEIDEGPQKEGPLKDFDPDTLISLTAPKPCSKFYKGKHYLGGRFVSKVITKKFNLSLPPYPGIDQVVDITNKPLSMV
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity).  May have a role in meiosis.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, Meiotically up-regulated gene 182 protein, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus.
Protein: YBEY_STRSY
Sequence: MYIEMIDETGQVSAQMQEQITELLQFAAEKIGKQNKEMAVTFVDNKRVHEVNLEYRGIDRPTDVVSLEYKPESEIVFDEEDLLDNPELAEMMEDFDAYIGELYISIDKAREQAEDYGHSYEREMGFLAVHGFLHINGYDHYTPEEEAEMLGLQEEILTAYGLTRE
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBF_SYNS9
Sequence: MSQAPMATTPRNYPIFTVRWLALHTLGIPTVFFLGALAAMQFIRR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS20_COPPD
Sequence: MANTISAERRIRLTKKETAYNRYWRTTMKTYVKRAKKAIESGDREAAEAAVLKAQSVIDKVAVKGVIHKNEAARRKSRLMKLFNQKFQ
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RNH_SYNFM
Sequence: MRGRRRMPETPAIRKHVEIFADGACRGNPGPGGWGAVLRYHGKEKELSGYAEYTTNNQMELAAVIQALRALKEPCRVTITTDSRYLRDGISLWIHKWKQNGWKTRVKTDVRNKELWIALDEACLPHEIDWQWVKGHSGHPENERCDALARAAIDRHLREAATEE
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OGG1_RAT
Sequence: MLFSSSLSSSMRHRTLTSSPALWASIPCPRSELRLDLVLASGQSFRWREQSPAHWSGVLADQVWTLTQTEDQLYCTVYRGDKGQVGRPTLEELETLHKYFQLDVSLTQLYSHWASVDSHFQSVAQKFQGVRLLRQDPTECLFSFICSSNNNIARITGMVERLCQAFGPRLVQLDDVTYHGFPNLHALAGPEVETHLRKLGLGYRARYVCASAKAILEEQGGPAWLQQLRVASYEEAHKALCTLPGVGTKVADCICLMALDKPQAVPVDIHVWQIAHRDYGWQPKTSQTKGPSPLANKELGNFFRNLWGPYAGWAQAVLFSADLRQQNLSREPPAKRKKGSKKTEG
What is the function of this protein?
DNA repair enzyme that incises DNA at 8-oxoG residues.  Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA.  Has a beta-lyase activity that nicks DNA 3' to the lesion.
What are the official names of this protein?
N-glycosylase/DNA lyase.
What is the protein family that this protein belongs to?
Belongs to the type-1 OGG1 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells.
Protein: PDXH_GLUOX
Sequence: MSDIPLIDLKADPFALFAAWVSDAEKSEPNDPNAMAVATATPDGRPSVRMLLLKGVDERGFVFYTNLESRKGRELLANPHVALLFHWKSLRRQIRIEGPVEAVSAAEADAYFASRSRMSRLGAIASDQSRPLDDRSTFEERLKAVDEKYGDGPIPRPANWSGFRVLPEAIEFWQDRPYRLHDRAVWTRDGNGWNVTRLYP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: PSBK_PROM9
Sequence: MLILFNTFAELPEAYKAFAPTVDVLPLIPLFFFLLVFVWQAAVGFK
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: S38A2_BOVIN
Sequence: MKKAEMGRFNISPDEDSSSYSSNSDFNYSYPTKQAALKSHYADVDPENQNFLLESNLGKKKYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAFGMVGKLTASGSITMQNIGAMSSYLFIVKYELPLVIQALMNIEDTNGLWYLNGDYLVLLVSLVLILPLSLLRNLGYLGYTSGLSLLCMMFFLIVVIFKKFQISCPAEIAFLVNETVNSSLTQPATFLPDMGFNRTESDSCQPRYFIFNSQTVYAVPILTFSFVCHPAILPIYEELKGRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYGHVESELLHTYSSVMETDILLLIVRLAVLVAVTLTVPVVIFPIRSSITHLLCASKEFSWWRHSVITVSILVFTNLLVIFVPNIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMKSVQKIGAMFFLLSGIVVMTGSMALIVLDWVHNAPGGGH
What is the function of this protein?
Symporter that cotransports neutral amino acids and sodium ions from the extraccellular to the intracellular side of the cell membrane.  The trasnport is pH-sensitive, Li(+)-intolerant, electrogenic, driven by the Na(+) electrochemical gradient and cotransports of neutral amino acids and sodium ions with a stoichiometry of 1:1.  May function in the transport of amino acids at the blood-brain barrier (By similarity).  May function in the transport of amino acids in the supply of maternal nutrients to the fetus through the placenta (By similarity).  Maintains a key metabolic glutamine/glutamate balance underpinning retrograde signaling by dendritic release of the neurotransmitter glutamate (By similarity).  Transports L-proline in differentiating osteoblasts for the efficient synthesis of proline-enriched proteins and provides proline essential for osteoblast differentiation and bone formation during bone development (By similarity).
What are the official names of this protein?
Sodium-coupled neutral amino acid symporter 2, Amino acid transporter A2, Protein 40-9-1, Solute carrier family 38 member 2, System A amino acid transporter 2, System A transporter 1, System N amino acid transporter 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Note=Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes. May localize to an endosomal compartment. Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal.
Protein: RS19B_YEAST
Sequence: MAGVSVRDVAAQDFINAYASFLQRQGKLEVPGYVDIVKTSSGNEMPPQDAEGWFYKRAASVARHIYMRKQVGVGKLNKLYGGAKSRGVRPYKHIDASGSINRKVLQALEKIGIVEISPKGGRRISENGQRDLDRIAAQTLEEDE
What is the function of this protein?
Required for proper maturation of the small (40S) ribosomal subunit.  Binds to 40s pre-ribosomal particles, probably required after association of NOC4 but before association of ENP1, TSR1 and RIO2 with 20/21S pre-rRNA.
What are the official names of this protein?
40S ribosomal protein S19-B, RP55B, S16a, Small ribosomal subunit protein eS19-B, YS16B.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS19 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_BRASB
Sequence: MLNSLDLEGRPEDTRVVVAMSGGVDSSVTAALLKSEGYDVVGITLQLYDHGAATHRKGACCAGQDIHDARNVAERLGIPHYVLDYEDRFRESVIDNFAASYASGETPVPCIECNRAIKFGDLLKTARELGASVLATGHYVASRRLADGSRALVCAADADRDQSYFLFATTREQLDYLRFPLGDMTKPEVRELARRFGLEVADKHDSQDICFVPTGRYTDIIGKLRPNAMEPGEIVDLNGRVLGAHQGIANYTIGQRKGLGIAAGAPLYVVKLDVATRRVVVGPREALRTHRITLREVNWIGDGVLDAAVRDGLELFVRVRSTRPPQPAWLRGADGQYEVELVAGEEGVSPGQACVFYDAASGRARVLGGGFIQSAVAESRTTAGLVRPQRVAEPVRG
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNC_HELPJ
Sequence: MKNKRSQNSPYVTPDNPYLTLEKALGYSFKDKRLLEQALTHKSCKLALNNERLEFLGDAVLGLVIGELLYHKFYQYDEGKLSKLRASIVSAHGFTKLAKAIALQDYLRVSSSEEISKGREKPSILSSAFEALMAGVYLEAGLAKVRKIIQNLLNRAYKRLDLEHLFMDYKTALQELTQAQFCVIPTYQLLQEKGPDHHKEFEMALYIQDKMYATAKGKSKKEAEQQCAYQALQKLKEAK
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COC1B_CONCL
Sequence: MKLTCVLVVLLLLLPYGDLITNNYIRGAARKVTPWRRNLKTRDVCDSLVGGHCIHNGCWCDQDAPHGNCCDTDGCTAAWWCPGTKWD
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels.  This toxin reversibly blocks voltage-gated sodium channel in cephalopods (tested on squid giant-fiber-lobe neurons) with an inhibitor constant (Ki) of 15 nmol/l, with no alteration in the voltage dependence of sodium conductance or on the kinetics of inactivation.  Has no effect on sodium channels of the two gastropod S. luhuanus and A. californica (which are not natural prey).
What are the official names of this protein?
Mu-conotoxin cal12b, Conotoxin Cal 12.1.1b, Conotoxin CalTx 12.1.1B.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: NEP_I03A1
Sequence: MDPNTVSSFQDILVRMSKMQLTSSSEDLNGMITQFESLKLYRDSLGETVMRMGDFHSLQIRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRAFSFQLI
What is the function of this protein?
Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs).  Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell.  Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain.  This domain is believed to allow recognition of RNPs bound to the protein M1.  Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized.  Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane.  May down-regulate viral RNA synthesis when overproduced.
What are the official names of this protein?
Nuclear export protein, NEP, Non-structural protein 2, NS2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses NEP family.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: NUDC_YERPE
Sequence: MELQLTGKESGWWIVSHENKLWLPKGELPQGNAANWSLQGTTARQIGEWQGQSVWLIRQMMPSGMGSVRQLLDVDRGLFQLAGRGVQLAEFYRSHRFCGYCGHEMHASRTEWASLCNHCRERYYPQIAPCVIVAIRRGDEILLAQHVRHRGGINTVLAGFVEVGETLEQAVSREVLEESNIHIKNLRYVTSQPWPFPHSLMMAFMADYDSGELCHDPKELLNAGWYRYDQLPLLPPPGTVARRLIEDTVVLCREHSDLSQ
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: PEP_DROME
Sequence: MVSVKVNGNPQNRLVNNAKVNGNMAFRGNQNRNRNFGGGNNNYGGPMGANRMGGMNMSPWESQNPGGGQFGNNMRQGGGQMNAQAINLANNLLNNLFRNQNPPSLLDLPRGGGGMGNRNQRGGPMVSRGGGAGNRLNNRRGQGGGFQNRGATGSGPKPPPKQGGGGIRKQNAFDRAKKLLAKNANQNKKKEPTPGEKKIESPTKESPYASVPNDMFYCHLCKKHMWDANSFENHIKGRTHLMMREGIEESYRLKANMIRQEAKIAEQLKSIEFDRLKRMGKSKQRQLDYCTMCDLNFHGHISTHRKSEGHLQLKKFLHPKCIECNKEFATRIDYDTHLLSAEHLKKAAENNTKVGERKRQTLPISTEEEETRDLRLPQKRKKKPVKKEGEAADGEAKKEGAGDGEGAEGDEAEGEEAKEGEEAADETKEGDELNESQEEEEVALPVDPEDCILDFNDGDEIPSEVDTRLPKYNWQRAVGPGLISKLECYECSVCSKFFDTEVTAEIHSRTATHHRNFLKFINEKSSDTKIAQKRAAAALEENERKKRKVEEAEAPAAEGAAEETTEGAEGELYDPSEATGDDEDVEMVDDNAEGEGEGEGDEEAEAEVEEDGAGQDNGEEEMEAQEEEGQEGEQEPEPEPAPVQTPAPAEPAPPAKTPAKTPTKAAAPAAVASPAAAATSADASPSPAKKATPARAAAGAKATPQRQRARGRYNRY
What is the function of this protein?
May play a role in the process of early and late gene activation, or possibly in RNA processing, for a defined set of developmentally regulated loci.
What are the official names of this protein?
Zinc finger protein on ecdysone puffs.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=It is associated with the active ecdysone-regulated loci on polytene chromosomes, and on some heat shock-induced puffs. Its distribution pattern follows the changes of puffing patterns in the developmental program, or following heat shock.
Protein: EX7S_STRPJ
Sequence: MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKELQATLDKAEKTLVKVMQEDGTESDFE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CCA_VIBC3
Sequence: MQIYLVGGAVRDQLLQLPVYDRDWVVVGSSPQAMLAAGFQAVGKDFPVFLHPNSKEEHALARTERKTGVGYTGFACHYAPDVSLEDDLLRRDLTINAMAQDNSGQLIDPYGGQRDLAAKVLRHVSPAFVEDPLRVLRVARFAAKLHHLGFTVAEETMQLMAKIVQSGELQHLTAERVWQEWHKSLSTNHPEVFLQVLRDCGALAVVLPEIDRLFGVPQPEKWHPEIDTGIHTLMVAKQAAQLSDSLPVRFAAQVHDLGKGVTPPSEWPSHKLHCHTGLNIIESLCERIRVPNEFRDLALAVCAQHSNIHRADELKPTTKLKVLGLLDVWRKPERLEQVLLCCEADHRGRLGLENEPYPQREIFLRAYQAALGVAVQAVIADGFHGKQIKEELDKRRVSAIEAL
What is the function of this protein?
Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template.  Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.  Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities.  These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
What are the official names of this protein?
Multifunctional CCA protein.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
Protein: TATA_CAUVN
Sequence: MGSMSWIHWVIVLGIVALLFGGRGKLSSIMGDAAKGIKAFKDGLKDESSSEVADNKAKSALPRTEAEAEELRKS
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.