PharMolix/UniProtQA huggingface dataset:
Protein: TRPA_THEP1
Sequence: MKGFIAYIPAGFPDLETTRKILIALNELGITGVEIGVPFSDPVADGPVIQLAHSVALRNGVTMKKILEMLGEISVDYDLYLMSYLNPIVNYPEGKEKLLDELKKLGVKGLIIPDLPLREVKNVNIAYPIVPFVAPNTKDEEIEFINSVQAPFVYYISRYGVTGEREDLPFADHIKRVKERIKLPLFVGFGISRHEQVEKVWEIADGAIVGSALVRIMEESPKDEIPKKVVEKVKELLGK
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: ACPS_GEOSL
Sequence: MIFGTGIDIVDITRFDRLVEEGNVRLFERLFTPHEMEYCAGKARSSQHYALRFAAKEAFLKACGLGLREGMTWHDVEVVNDTLGKPELKLHGKALKLATDLSLSRTFVSLSHDGAYAVALVVLERP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7S_LISW6
Sequence: MATKKKTFEEAIAELETIVEALENGSASLEDSLDMYQKGIELTKLCQDKLQTAEKRMAKVVTDTGEEIPFEADGE
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_LACDA
Sequence: MFVKTGDKVKVIAGSEKGKEGTVLSVNVKENRVVVKGVNMIKKATKASASNANGGVVETEGSIHASNVKVIAKAESNKD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: RS8_CARRP
Sequence: MVMITLINNIIRLINSYNSGKNICICIYSKISMLLLGILIEKKIIKSFFVLLFKNKKKIFVIIKTIILIKLFSKPSNKRYIKNKYLKKIEFNNGLIISTNIGLLTIRECLKLKIGGKIFFSII
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: RSME_TREPA
Sequence: MNIVLFEQEEVVHGCAVLSFRDSRFCHIKRVLKLSAGACFKAGIINGVKGSARISLATEKYLVAVFEKLEYEDCALFPLHLVIGFPRPIQLRRILRDVSSLGISSIHLVGTELGERSYLDSGLAHMEKMHTYLIRGLEQAGGTKLPLITVSESVRTFCSQHTHILGDSTHQKLILDTKNTLTDLGSAALRGDVLWIAIGSERGWTESERLLFSAMGFRAVDMGRRTLRTETAACAACAVVLANAHAWKRKIPRPGKRSSPISRKNP
What is the function of this protein?
Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA.  Acts on the fully assembled 30S ribosomal subunit (By similarity).
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase E, 16S rRNA m3U1498 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RsmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_ECODH
Sequence: MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQRNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSF2_CANAL
Sequence: MVLPKNLQGNLMPSEITFLAENELITILPRYSIKKIDLIGTSIPNLRAMRRELVPLWVALILKSQDKCSIVPPKWLTVAYLKERYEDEIRKPLQFSDLPWNWLELSKILLEKAPDDLSDPVDQLRSVIQDLRETRLVKSKKGLKELNESNIQLNGLSLLEINELRPFVIPVMNKLRQLYDTTQSNTINADDQDMEDASDDEDV
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.  Has a role in chromosome segregation (By similarity).
What are the official names of this protein?
DNA replication complex GINS protein PSF2.
What is the protein family that this protein belongs to?
Belongs to the GINS2/PSF2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYFB_PROMA
Sequence: MKVSLSWLNELVDIHCDVEELADSLSMAGFEVEELIDLSASLEGIVTGYVIDISPHPNADKLSVCKVDIGKSEAIQIVCGAKNIRSGIHVLVATEGTYLKDIDLTIKTSHLRGQISQGMICSLSELGLPPNNDGIAILEEMNIAIPKIGVCPKKQLGLDEIIFDLAITANRPDGLSMVGIAREVSAINNTKLKLPAIDLLHKDYKEFDHNVESKKFASRNEVYSLNLIDNLNGNNDSSEEVKSRLRNAGINSINAIVDLTNYTMLEQGQPLHAFDADLLCELTGKEVTINDFGIRKAKTGENLIGIDGIDYSLSSKVDVITCSNIIIAIAGIIGGKNSCVNKETRKIWLEAALFSPSSVRISSREIGKRTESSTRFEKGISPEITISSVERCLNLLTKTFDCQILEKWINRELVIEEQLLLLRREKINKTLGKVVEHKTNINAGDNSNNIDKSGESQINTLRNIDDHEIEQSLISLGCKLQKDVKGWLVEVPANRKLDLKREIDLIEEISRLIGYDRFDSNLPNPLRPGGLTPKQKIERKVRESLTSVGFQEVVTLSLVAKDQYSKNQVAISNPLLSETSHLRTNLWQEHLNICQRNMAYEQKGCWIYEIGKIYNIDSGRINETSLLCGALVGNKSIGQWQTETKNSSLDYFQSRGILHSALNSLNINITDEKLDENQLLHPGKSSMLKLEGKELGFFGELHPSKLSDLNIDYPIYIFELNFNLILQSSTRKNKLNISFKQFPTVPSMERDIALLVDNNIQSLDISNLIIKTGRPLVEDAYLIDRYEGDNIPKGKVSQAFRIRYRKNKDTLKEEEVSPIHDKIREKLKVEFSAELRS
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPB34_MYCTO
Sequence: MELAARMGETLTQAVVVAVREQLARRTGRTRSISLREELAAIGRRCAALPVLDTRAADTILGYDERGLPA
What is the function of this protein?
Antitoxin component of a possible type II toxin-antitoxin (TA) system.  The cognate toxin is VapC34 (By similarity).
What are the official names of this protein?
Putative antitoxin VapB34.
Protein: RRF_BORT9
Sequence: MEEYKALLDEKMSKVLLSLESEYKSLRTGRINSSLFDKVLVDYYGEKTPLTRVANVSIPEARLIVIQPWDKSLLSKIEQAILSSDLSMNPSSDGAVLRIKVPVLTVERRKEIVKQAKKIAEEYKVAARNVRQELNSKAKKQEKDSQITEDDLRRILDDIQRDTNSYIKKIDEIFDLKTKEIMEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATE_CLOBJ
Sequence: MSNLENLTSKIIEDANKEAEKLLSEAKKEENKIVNEKVKKGEKVKEQIIEKSKGEAKTKAERVISNTQLKVRNNKLEAKQEMINKVFDEAVIKLQNLPQEEYLNFIKNSILSLDIEGDEEIIVSPNDKNKIDISFILTLNNKLKAKGKKDLLKISNENRNIKGGFILYKNGIEINNSFEALVDSLRDELEQEIIEALFS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
V-type proton ATPase subunit E, V-ATPase subunit E.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase E subunit family.
Protein: AROA_HALLT
Sequence: MDVNVTSSTVRGTTRAPPSKSYTHRALLAAGYSDGATVRSPLVSADTKATARAVTAFGGAVEPESGERFDDADALVVDGFDGRPAVPDDVIDCANSGTTMRLVTAAAALADGTTVLTGDESLRSRPQGPLLEALGDLGVRAESTRGNGQAPLVVSGPLAGGEVAIPGNVSSQYVTALLMAGAVTEEGVEIDLTTPLKSAPYVDITLELLDDFGIEATPVGDGGDALDGAAGAAGFVVDGGQSYAPAGGSYTVPGDFSSISYLVAAGAVAAEPGEPVRIEGAVPSAQGDSAIVEIVERMGADIEWDREAGVITVRRSELSGVEVDVGDTPDLLPTIAALGAVADGDTRIMNCEHVRYKETDRVSAMAEELEKLGAKTTEEPDTLTVHGSESDLRGASVDGRADHRIVMALAVAALVAEGTTTIRGGEHVDVSFPNFFDAMADLGIAVERDGAGE
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTHT_METTF
Sequence: MNMDIASFFSGAGGLDLGFTKAGFNIVFANDNWKGCWKTFEKNHGIKINKKPIEWLKPSEIPDVVGFIGGPPCQSWSLAGSMCGADDPRGKTFYAYVDLVKEKDPLFFLAENVPGIVSRTHLPEFKRLVNSFIDIGYNVEYKVLNAKDYGVPQDRKRVFIVGYREDLNLKFEFPKPLNKKVTLRDAIGDLPEPKPALEKNRSNGENLEVPNHEYMTGTFSSRYMSRNRVRSWDEVSFTIQAGGRHAPCHPQANKMIKVGPDKFIFDPESPKPYRRLSVRECARIQGFPDDFIFYYKNVADGYTMVGNAVPVKLAEELAKKIKKDLEGVLN
What is the function of this protein?
A methylase that recognizes the double-stranded sequence 5'-GGCC-3', methylates C-3 on both strands, and protects the DNA from cleavage by the MthTI endonuclease.
What are the official names of this protein?
Type II methyltransferase M.MthTI, M.MthTI, Cytosine-specific methyltransferase MthTI, Modification methylase MthTI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: GREA_STRPQ
Sequence: MAEKTYPMTLTEKEQLEKELEELKLVRRPEIVERIKIARSYGDLSENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVIVQEVGTTDKDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVRIESPAATYDVEIISVEKTN
What is the function of this protein?
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus.  GreA releases sequences of 2 to 3 nucleotides.
What are the official names of this protein?
Transcription elongation factor GreA, Transcript cleavage factor GreA.
What is the protein family that this protein belongs to?
Belongs to the GreA/GreB family.
Protein: PARP2_MOUSE
Sequence: MAPRRQRSGSGRRVLNEAKKVDNGNKATEDDSPPGKKMRTCQRKGPMAGGKDADRTKDNRDSVKTLLLKGKAPVDPECAAKLGKAHVYCEGDDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKTGQHSLVTCSGDLNKAKEIFQKKFLDKTKNNWEDRENFEKVPGKYDMLQMDYAASTQDESKTKEEETLKPESQLDLRVQELLKLICNVQTMEEMMIEMKYDTKRAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALVEACNEFYTRIPHDFGLSIPPVIRTEKELSDKVKLLEALGDIEIALKLVKSERQGLEHPLDQHYRNLHCALRPLDHESNEFKVISQYLQSTHAPTHKDYTMTLLDVFEVEKEGEKEAFREDLPNRMLLWHGSRLSNWVGILSHGLRVAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAQGLLRGKHSTKGMGKMAPSPAHFITLNGSTVPLGPASDTGILNPEGYTLNYNEFIVYSPNQVRMRYLLKIQFNFLQLW
What is the function of this protein?
Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair (PubMed:10364231, PubMed:12065591).  Mediates glutamate, aspartate or serine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units (PubMed:12065591).  Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage (By similarity).  Mediates glutamate and aspartate ADP-ribosylation of target proteins in absence of HPF1 (By similarity).  Following interaction with HPF1, catalyzes serine ADP-ribosylation of target proteins; HPF1 conferring serine specificity by completing the PARP2 active site (By similarity).  PARP2 initiates the repair of double-strand DNA breaks: recognizes and binds DNA breaks within chromatin and recruits HPF1, licensing serine ADP-ribosylation of target proteins, such as histones, thereby promoting decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand breaks (By similarity).  HPF1 initiates serine ADP-ribosylation but restricts the polymerase activity of PARP2 in order to limit the length of poly-ADP-ribose chains (By similarity).  Specifically mediates formation of branched poly-ADP-ribosylation (By similarity).  Branched poly-ADP-ribose chains are specifically recognized by some factors, such as APLF (By similarity).  In addition to proteins, also able to ADP-ribosylate DNA: preferentially acts on 5'-terminal phosphates at DNA strand breaks termini in nicked duplex (By similarity).
What are the official names of this protein?
Poly [ADP-ribose] polymerase 2, PARP-2, mPARP-2, ADP-ribosyltransferase diphtheria toxin-like 2, ARTD2, DNA ADP-ribosyltransferase PARP2, NAD(+) ADP-ribosyltransferase 2, ADPRT-2, Poly[ADP-ribose] synthase 2, pADPRT-2, Protein poly-ADP-ribosyltransferase PARP2.
What is the protein family that this protein belongs to?
Belongs to the ARTD/PARP family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Recruited to DNA damage sites.
Protein: APAG_PSEF5
Sequence: MSDPRYQVDVSVVTRFLADQSQPEQNRFAFAYTITVQNNGSLPAKLLSRHWVITDGDGHVEEVRGAGVVGQQPLIAAGKSHTYSSGTVMTTRVGNMQGSYQMLAEDGKQFDAVIAPFRLAVPGALH
What are the official names of this protein?
Protein ApaG.
Protein: RL23_STRPM
Sequence: MNLYDVIKKPVITEKSMIALEAGKYTFEVDTRAHKLLIKQAVEAAFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAAEAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y083_STAAC
Sequence: MKRLNKLVLYISFLILVISFTAGCGIGKEAEVKKSFEKTLSMYPIKNLEDLYDKEGYRDDEFDKNDKGTWIIGSEMVVQPKGERMKSKGMVLYMNRNTKTTTGKYIVSETLHDEDGRPKSKDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYGSFKDLSKYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYKIPTNKAPKLLLKGSGDLKGSSVGYKDIEFTFVEKKGENTFFTDSLHLEPSEDK
What are the official names of this protein?
Uncharacterized lipoprotein SACOL0083.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: U95_HHV6Z
Sequence: MSSNLEDLLWQQILSMDPAELLSDNAISSTCDENIAAGHHFTQSPHVEMSVQSTTSAGHTGVMTTQSQFSNGVRDQNRESLSTLTGLSLESINNQINVQPTQMTFQPISPPMQGQNYVYSNNMINPIKPRSIIKSHGHSMGEMSFADHSLYVNAQPPVQQPQLKSLVGMHPCMTATSQGKYQTNKTVGPPSISASQITTGNAGIRPGEYQSVHNQSSVNGSKSYEITTASGDEWILTTPGGQSWTLKRNPPNPPNNRTNSVVNKAQQVSHAQPYVSGSSDGFYQGAALQSCAYVNTPGFTPVCETQNMNNSQATQLSASMNCINALQTTMDAIVTSTSKPVGAVSNNRGANFGMGGMENYMDNNSPWNQYCKVQDIVSQNCSQGKVVSSTPGIAPNLMKGNGLNVYGHVGCVDAAISDKQGGTANVASSLLNPEHQDWMRVTGTSTNLLNNINAETKMENYGFPENGNVHGAVNTALPLTLSSGQPYTSVPQHGACEGNGTIPVVQICSPNTAFKAHYSLLGTVDENNPLSVRESIQDTSFSNGCAPQLSSPGGNPTIIAHSMIGNNGTPNKDVCKPTPSLRAIKKLNFDYDDRGENIGFPSKLAALLSMGENMSKMDNPCYGTSLAQFEESHQQNASEGKISIADLEFSEEDDVLSSAASVSCNDNCVMKIGASQQGTTVADLQQGFKQQMNGEFSMFAVDGNIKTQEMSNDCASNVTDNACAIRQNKRMHCEIGISEDGRVREEEKCSDVAIHVPRKSARIHNMKSEGVTCGMCVTAADSTRQDASGGSSSGTKKGEKLQGLWKGYQDDDDSELTELSDTDSDNDVQNCHGVRKTGSKTYSSVFFNPDYRQAKRLLADIPYRRWIPDTFNMEEHEGPFLPIVTRPPTVFMGGRRRRTYLRRSVTSIGPLSKLTYFKELLQSYVLRNSNCYLSIGWPAKHRVYIMSEEKLGYNHIPTLREMFPLPPGWMIVLGIVGSETPAALYKHMVVLLCENKWVLLHNYRDSKHELYFAASDLKQFMEEGLSRCDCIYYEKSVPYGVAMEDSVREFLRNSKTFQSLMEYRKNMHGSTWTFNGMPGRLGDRVIHICNPELVNSIPADEAIRYEGKPLYFFAFVTTFKSHPGSKANVLIAADKNLGIYGYHKGRPRIRYLCKNVQAFFRAGVRKMYLDYEIPSKTLLAVSEDDYLCILQKAPCLLLKPAVFRKTFSQEGK
What are the official names of this protein?
Uncharacterized protein U95.
Protein: MX_STRP9
Sequence: MARQQTKKNYSLRKLKTGTASVAVALTVLGAGFANQTEVRAEGVNATTSLTEKAKYDALKDENTGLRGDQTKLVKKLEEEQEKSKNLEKEKQKLENQALNFQDVIETQEKEKEDLKTTLAKATKENEISEASRKGLSRDLEASRAAKKELEAKHQKLEAENKKLTEANQVSEASRKGLSNDLEASRAAKKELEAKYQKLETDHQALEAKHQKLEADLPKFQRPSRKGLSRDLEASREANKKVTSELTQAKAQLSALEESKKLSEKEKAELQAKLDAQGKALKEQLAKQTEELAKLRAEKAAGSKTPATKPANKERSGRAAQTATRPSQNKGMRSQLPSTGEAANPFFTAAAATVMVSAGMLALKRKEEN
What are the official names of this protein?
Virulence factor-related M protein.
What is the protein family that this protein belongs to?
Belongs to the M protein family.
What are the subcellular locations of this protein?
Secreted, cell wall; Peptidoglycan-anchor.
Protein: YQGF_MANSM
Sequence: MLMGICALAFDFGTKSIGCAVGQSITGTAQALPAFKAQNGIPNWDSIEKCLKEWKPDILVVGLPLNMDGTEQEFTSRARKFANRLHGRFGVKVELQDERLTTTEARTEIFQRGGYKALNKSKVDGISAALILESWFERHS
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SA1B2_ARATH
Sequence: MDGDELTEQETALYDRQIRVWGAGAQRRLSKSHVLVSGIKGTVAEFCKNIVLAGVGSVTLLDDRLVTTEVFNANFLILPDENAYVGKTVAEICCDSLKDFNPMVHVSIEKGDLSTLGVDFFEKFDVVVIGYSSRATKKAVNEKCRNLAKDVAFYTVDCRGSCGEIFVDLQNYKYTKKKLDETVECELTFPSFEEAVSVPWKPMPRRTAKLYFAMRVIELFEETEGRKPGECSLSDLPRVLKLKKELCEGNSVSENHIPDILLERLVSNNTEFPPACAIIGGILGQEVIKVISGKGEPLKNFFYFDAEDGKGVIEDLSHKL
What is the function of this protein?
The dimeric enzyme acts as an E1 ligase for SUMO1 and SUMO2.  It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.  Functionally redundant with its paralog SAE1A (By similarity).
What are the official names of this protein?
SUMO-activating enzyme subunit 1B-2, SUMO-activating enzyme subunit 1-2, Ubiquitin-like 1-activating enzyme E1A.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DHPS_STAAW
Sequence: MTKTKIMGILNVTPDSFSDGGKFNNVESAINRVKAMIDEGADIIDVGGVSTRPGHEMVSLEEEMNRVLPVVEAIVGFDVKISVDTFRSEVAEACLKLGVDMINDQWAGLYDHRMFQIVAKYDAEIILMHNGNGNRDEPVVEEMLTSLLAQAHQAKIAGIPSNKIWLDPGIGFAKTRNEEAEVMARLDELVATEYPVLLATSRKRFTKEMMGYDTTPVERDEVTAATTAYGIMKGVRAVRVHNVELNAKLAKGIDFLKENENARHNLS
What is the function of this protein?
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
What are the official names of this protein?
Dihydropteroate synthase, DHPS, Dihydropteroate pyrophosphorylase.
What is the protein family that this protein belongs to?
Belongs to the DHPS family.
Protein: PNP_PELPD
Sequence: MEHVVDVEFGGKMVTISTGKMAKQANGAVVVKSGDTMVLVTAVAQKEAKEGQDFFPLTVNYTEKAYAGGKIPGSFFRREARPSDPETLTCRLIDRPIRPLFPENFLNDTQIIATVVSADKDHDPRILSMLGASAALEVSDIPFQGPIAGVKVGRVDGRLICNPTADELELSDMEIVVAASRDAIIMVEGEARFVSEDDMLDAIFFGHAAVQPVLEAQEKLKQLAGVAKRDVPPPVVDQALLARVRELASERMSAAVKIKSKQERHNQIDLITAETTASLAAEFEGNEKQIRAFLGDLEYECVRADVLNSGVRIDGRDTVTIRPIATEAGLLPRTHGSALFTRGETQALVVTTLGTSSDEQRMDSLYGEYRKRFLLHYNFPPFSVGETSFRLGPGRREIGHGMLAERALSAILPKHDDFPYTIRIVSETLESNGSSSMAAVCGGCMSLMDAGVPISAPVAGIAMGLIKEGEKVAILSDILGDEDHLGDMDFKVAGSSDGITALQMDIKIGGVTREIMQKALAQAREGRLHILGKMAETLGAPRPEMSSFAPRITTIWVKTDKIRDVIGTGGKNIRNITETTGVTVDIEDTGRINIASTSKEACDLAIQMIRGLTDEAEEGKLYMGIVKKIMDFGAFVEILPGTDGLVHISELDTKRVKTVTEVLNEGDRVLVKCIGVDKNGKVKLSRKEALGLNPDGTPATDAPAGE
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RBL_COLPU
Sequence: TKASVGFKAGVKDYKLTYYTPDYVTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYNIEPVAGEEHQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAERIYKSQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKAIKFEFPAMDTL
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CET1_CANAL
Sequence: MNVGSILNDDPPSSGNANGNDDNTKIIKSPTAYHKPSVHERHSITSMLNDTPSDSTPTKKPEPTISPEFRKPSISSLTSPSVAHKPPPLPPSSSSVGSSEHSSARSSPAITKRNSIANIIDAYEEPATKTEKKAELNSPKINQSTPVPKLEEHENDTNKVEKVVDSAPEPKPKKEPQPVFDDQDDDLTKIKKLKQSKKPRRYETPPIWAQRWVPPNRQKEETNVDDGNEAITRLSEKPVFDYTTTRSVDLECSITGMIPPSSITRKIAEWVYANFSNVEEKSKRNVELELKFGKIIDKRSGNRIDLNVVTECIFTDHSSVFFDMQVEEVAWKEITKFLDELEKSFQEGKKGRKFKTLESDNTDSFYQLGRKGEHPKRIRVTKDNLLSPPRLVAIQKERVADLYIHNPGSLFDLRLSMSLEIPVPQGNIESIITKNKPEMVREKKRISYTHPPTITKFDLTRVIGNKTEDKYEVELEAGVMEIFAAIDKIQKGVDNLRLEELIEVFLNNARTLNNRLNKIC
What is the function of this protein?
First step of mRNA capping.  Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
What are the official names of this protein?
mRNA-capping enzyme subunit beta, mRNA 5'-phosphatase, mRNA 5'-triphosphate monophosphatase.
What is the protein family that this protein belongs to?
Belongs to the fungal TPase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL17_RICRS
Sequence: MRHKIKGRKLNVTSSHRQAMLANMAVALVTHEQIKTTLPKAKELRPYIETLITKAKKADLMVRRSVLSKIKDKTAVEKLINILGTRYKDRPGGYTRIIKAGFRYGDLAPIAYIEFVDRDINAKGNIQQDANEEIKN
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: IF2_STRSY
Sequence: MSKKRLNEIARELGVSSKEVVAKAQELGFEVKSHASSVDEASAKRLAESFGGQKSEATKVAAKVSKPEKVDETPKVETAKVEKAKETQPVVKEEVAASAVQSASHRPQSRNFKAEREARAKEQAAKRAQNQGKGGQAKSDQDRRDNRQLGQGRSNNERNDRRDNRRDQRPEERKDNRFGDRRDNRDNRRQDNRSGRLARFEQREAAKPAGPKIDFKARAAALKAEQNAEYARTSEERFRQAQEAKKQPKKPKEIKFEEPVVESKPFVKPALVASVPEQVAETTVDTRRKKQARPDKKRDFNSDEEDGPRKQQRNRNSQNQVRNQRTSNWNNNKKNKKGKANQPAKPVTERKFHELPTEFEYTAGMTVAEIAKRIKREPAEIVKKLFLMGVMATQNQSLDGDTIELLMVDYGIEAKEKVEVDNADIERFFVEEGYLNEEEMTERPPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKITFLDTPGHAAFTSMRARGASVTDLTILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVISTAWGGESEFVEISAKFNQNIDELLETVLLVAEIQELKADPTVRAIGTVIEAHLDKGKGAVATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKTAGPSTPVSITGLNETPMAGDHFAVYEDEKSARAAGEERAKRALLKQRQATQRVSLENLFDTLKAGEVKSVNVIIKADVQGSVEALASSLQKIEVEGVRVNIVHSAVGAINESDITLAEASNALVIGFNVRPTAEARSQAEADDVEVRLHSIIYKVIEEMEDAMKGMLDPEYEEKIIGEAIIRETFKVSKVGTIGGFMVVRGKVTRDSSVRVIRDGVVVFDGKLASLKRYKDDVKEVGNAQEGGLMIENYNDLKVDDTIEAYIMEEIKK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.