PharMolix/UniProtQA huggingface dataset:
Protein: PDEA_ECOLI
Sequence: MFVEHNLIKNIKIFTLAFTLTVVLIQLSRFISPLAIIHSSYIFLAWMPLCVMLSILFIFGWRGVVPVLCGMFCTNLWNFHLSFLQTAVMLGSQTFVVLCACAILRWQLGTRWRYGLTSRYVWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDADAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLGKEKRAFTLSWLAALSVLLLLLCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLNYNQNFLQGVETEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLLPNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSICRTLLPLMQENEKLYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGRFDGNQETLQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYAQPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATHPCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYHISPQAVILEITEEQAFSNAESSMYNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRSITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD
What is the function of this protein?
Phosphodiesterase (PDE) that catalyzes the hydrolysis of cyclic-di-GMP (c-di-GMP) to 5'-pGpG.
What are the official names of this protein?
Probable cyclic di-GMP phosphodiesterase PdeA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KAD1_ARATH
Sequence: MARLVRVARSSSLFGFGNRFYSTSAEASHASSPSPFLHGGGASRVAPKDRNVQWVFLGCPGVGKGTYASRLSTLLGVPHIATGDLVREELASSGPLSQKLSEIVNQGKLVSDEIIVDLLSKRLEAGEARGESGFILDGFPRTMRQAEILGDVTDIDLVVNLKLPEEVLVDKCLGRRTCSQCGKGFNVAHINLKGENGRPGISMDPLLPPHQCMSKLVTRADDTEEVVKARLRIYNETSQPLEEYYRTKGKLMEFDLPGGIPESWPRLLEALRLDDYEEKQSVAA
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis, adenine nucleotide metabolism and plant growth.
What are the official names of this protein?
Adenylate kinase 1, chloroplastic, AK 1, AtPADK1, ATP-AMP transphosphorylase 1, ATP:AMP phosphotransferase, Adenylate monophosphate kinase 1, AMK1.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma.
Protein: CDC37_HUMAN
Sequence: MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQVAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEYEEEERKKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKASEAKEGEEAGPGDPLLEAVPKTGDEKDVSV
What is the function of this protein?
Co-chaperone that binds to numerous kinases and promotes their interaction with the Hsp90 complex, resulting in stabilization and promotion of their activity (PubMed:8666233).  Inhibits HSP90AA1 ATPase activity (PubMed:23569206).
What are the official names of this protein?
Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37.
What is the protein family that this protein belongs to?
Belongs to the CDC37 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APT_STRTD
Sequence: MKLEDYIATIENYPKEGVTFRDISPLMADGNAYSYAIREIVQYATDKKIDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPRKVISVDYEKEYGVDTLCMHADAIKPGQRVLIVDDLLATGGTVKATIEMIERLGGVVAGCAFLIELDGLNGREAIEGYDAKVLMNFPG
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TBC20_HUMAN
Sequence: MALRSAQGDGPTSGHWDGGAEKADFNAKRKKKVAEIHQALNSDPTDVAALRRMAISEGGLLTDEIRRKVWPKLLNVNANDPPPISGKNLRQMSKDYQQVLLDVRRSLRRFPPGMPEEQREGLQEELIDIILLILERNPQLHYYQGYHDIVVTFLLVVGERLATSLVEKLSTHHLRDFMDPTMDNTKHILNYLMPIIDQVNPELHDFMQSAEVGTIFALSWLITWFGHVLSDFRHVVRLYDFFLACHPLMPIYFAAVIVLYREQEVLDCDCDMASVHHLLSQIPQDLPYETLISRAGDLFVQFPPSELAREAAAQQQAERTAASTFKDFELASAQQRPDMVLRQRFRGLLRPEDRTKDVLTKPRTNRFVKLAVMGLTVALGAAALAVVKSALEWAPKFQLQLFP
What is the function of this protein?
GTPase-activating protein specific for Rab1 and Rab2 small GTPase families for which it can accelerate the intrinsic GTP hydrolysis rate by more than five orders of magnitude (PubMed:23236136).  Involved in maintaining endoplasmic reticulum structure (PubMed:24891604).
What are the official names of this protein?
TBC1 domain family member 20.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL14_BACAN
Sequence: MIQQESRLKVADNSGARELLTIKVLGGSGRKYANIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKSGARRPDGSYIKFDENAAVIIKDDKSPRGTRIFGPVARELRDSNFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y904_XANC8
Sequence: MDLPDVAAVQHESRQLDLASSAAELHGGLCGWLSGGGADSADWLARILADTAQVAPAQGGALDQMRQATVAQLEDRDFAFELLLTEDGAPLPARTDALFDWCRAFLGGFGLAAQQRPALSEEGEEALQDLARLAQASSDDFDTAEEDDTALAEIEEFVRVAVLLLHGDCVMGPRFRQRLN
What are the official names of this protein?
UPF0149 protein XC_0904.
What is the protein family that this protein belongs to?
Belongs to the UPF0149 family.
Protein: NADB_ARATH
Sequence: MAAHVSTGNIHNFYLAGQVYRGQAFSWSSASTFMANPFKEPSWSSGVFKALKAERCGCYSRGISPISETSKPIRAVSVSSSTKYYDFTVIGSGVAGLRYALEVAKQGTVAVITKDEPHESNTNYAQGGVSAVLCPLDSVESHMRDTMVAGAHLCDEETVRVVCTEGPERIRELIAMGASFDHGEDGNLHLAREGGHSHCRIVHAADMTGREIERALLEAVLNDPNISVFKHHFAIDLLTSQDGLNTVCHGVDTLNIKTNEVVRFISKVTLLASGGAGHIYPSTTNPLVATGDGMAMAHRAQAVISNMEFVQFHPTALADEGLPIKLQTARENAFLITEAVRGDGGILYNLGMERFMPVYDERAELAPRDVVARSIDDQLKKRNEKYVLLDISHKPREKILAHFPNIASECLKHGLDITRQPIPVVPAAHYMCGGVRAGLQGETNVLGLFVAGEVACTGLHGANRLASNSLLEALVFARRAVQPSTELMKRTRLDVCASEKWTRPVVATARLLGDEVIAKIIALTKEVRRELQEVMWKYVGIVRSTIRLTTAERKIAELEAKWETFLFEHGWEQTVVALEACEMRNLFCCAKLVVSSALARHESRGLHYMTDFPFVEESKRIPTIILPSSPTTASWSSRRLQNISSSSLIDC
What is the function of this protein?
Catalyzes the oxidation of L-aspartate to iminoaspartate.  Can complement nadB-deficient E. coli mutant.  Plays a role in stomatal immunity.
What are the official names of this protein?
L-aspartate oxidase, chloroplastic, Protein FLAGELLIN-INSENSITIVE 4.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PETG_ADICA
Sequence: MVEALLSGIVLGLIPITLAGLFVTAYLQYRRGDQLDIR
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PCKA_ENT38
Sequence: MRVNDLTPQDLKAYGINDVQELVYNPDYDTLYQEELNPALEGYERGVLTNTGAIAVDTGIFTGRSPKDKYIVRDDTTRDTLWWADKGKGKNDNKPLSQETWQHLKGLVTQQLSGKRLFIIDAFCGANADTRLSVRFITEVAWQAHFVKNMFIRPTDEELQDFEPDFIVMNGAKCTNPQWKEQGLNSENFIAFNLTERIQLIGGTWYGGEMKKGMFSVMNYLLPLQGIASMHCSANVGEEGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIRLSAEAEPDIFHAIRRDALLENVTVRADGTVDFDDASKTENTRVSYPIYHIDNIVKPVSKAGHASKVIFLTADAFGVLPPVSRLTASQTQYHFLSGFTAKLAGTERGVTEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAIIDGSLDDAETFTLPMFDLAIPTKLPGVDTHILDPRNTYGSPEQWQEKAEALAKLFIENFEKYTDTPAGAALVSAGPR
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACS_LACSL
Sequence: MKTEKKVLDELSLHASAKMGARDVESSMNADSTPVLASVAVSMELLPTASVLYSDVAGCFKYSAKHHC
What is the function of this protein?
Inhibits the growth of selected species of the genera Lactobacillus, Pedicoccus, and Leuconostoc.
What are the official names of this protein?
Bacteriocin lactocin-S.
Protein: CINAL_SHEB5
Sequence: MKLEMICTGEEVLAGQIVDTNAAWFASTMMEHGVEIQRRVTVGDRLEDLIAVFQERSLHADVILVNGGLGPTSDDMSALAMAKAKGEPLVENVEWRERLEEWFTRNNREMPLSNLKQAMLPASAVMVDNPVGTACGFRVKLNRAWLFFTPGVPFELKHMVTEQFVPFIRDEFNLDSKVALKKLLTIGQGESALADKLEPLELPEGITIGYRSSMPHIEIKIFARGEKAIAVLPRVAGHIKMVLGTAVVAEDKATLAEEIHYKLLNSGLTLSVAESCTGGMITSQLVDFSGSSSYLQHGLVTYSNESKVRVLGVNPSTLDDHGAVSIATVEEMAKGARQILDSDYALATSGIAGPDGGTDEKPVGTVAIALATRGGVYSQMIKLPRRSRDLVRSLSAAVAYDMLRRELLAEAVIVDYQSIGRFSK
What are the official names of this protein?
CinA-like protein.
What is the protein family that this protein belongs to?
Belongs to the CinA family.
Protein: PER5_VITVI
Sequence: MSSKRVTWLSLTWVLVFLCLSVELEAQLQVGFYRTSCGLAEFIVKDEVRKGFIRDSGVAPGLVRMHFHDCFVRGCDGSVLIDSTPSNTAEKDSPANNPSLRGFEVIDSAKARLEAVCKGVVSCADIVAFAARDSVEITGGLGYDVPAGRRDGRISLASEASTNLPPPTFTVDQLTQFFSNKGLTQDEMVTLSGAHTIGRSHCSSFSNRLYNFNGTSGQDPTLDPQYAASLKTQCPQGSTNTNLVVPMNPSSPSITDVGYYVDVLRNRGLFTSDQTLLTDTTTATQVRQNAGNPFLWKNKFASAMVKMGQLGVLIGEAGQIRANCRVINS
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 5.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TVP23_PHANO
Sequence: METAQTAPAPGSLSWKLSSHPITLLTFLFFRISSLLVYLLGMRLLSSNFVLIFIVTILLLAMDFYYLKNIAGRRLVGLRWWNEVDGATGDGRWVFESADPESREQNATDKRFFWMALYVQPVLWVVMAVVALFGFNFIWLTLVAIALVLTITNTLAFSRCDKFSQASGFASNAMYGSGLARNLAGGLVSNWFRR
What is the function of this protein?
Golgi membrane protein involved in vesicular trafficking.
What are the official names of this protein?
Golgi apparatus membrane protein TVP23.
What is the protein family that this protein belongs to?
Belongs to the TVP23 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi- pass membrane protein.
Protein: RFAG_ECOLI
Sequence: MIVAFCLYKYFPFGGLQRDFMRIASTVAARGHHVRVYTQSWEGDCPKAFELIQVPVKSHTNHGRNAEYYAWVQNHLKEHPADRVVGFNKMPGLDVYFAADVCYAEKVAQEKGFLYRLTSRYRHYAAFERATFEQGKSTKLMMLTDKQIADFQKHYQTEPERFQILPPGIYPDRKYSEQIPNSREIYRQKNGIKEQQNLLLQVGSDFGRKGVDRSIEALASLPESLRHNTLLFVVGQDKPRKFEALAEKLGVRSNVHFFSGRNDVSELMAAADLLLHPAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIADANCGTVIAEPFSQEQLNEVLRKALTQSPLRMAWAENARHYADTQDLYSLPEKAADIITGGLDG
What is the function of this protein?
Involved in the addition of the first glucose residue to the lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core biosynthesis protein RfaG, Glucosyltransferase I.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
Protein: PDUC_SALTY
Sequence: MRSKRFEALAKRPVNQDGFVKEWIEEGFIAMESPNDPKPSIKIVNGAVTELDGKPVSEFDLIDHFIARYGINLNRAEEVMAMDSVKLANMLCDPNVKRSEIVPLTTAMTPAKIVEVVSHMNVVEMMMAMQKMRARRTPSQQAHVTNVKDNPVQIAADAAEGAWRGFDEQETTVAVARYAPFNAIALLVGSQVGRPGVLTQCSLEEATELKLGMLGHTCYAETISVYGTEPVFTDGDDTPWSKGFLASSYASRGLKMRFTSGSGSEVQMGYAEGKSMLYLEARCIYITKAAGVQGLQNGSVSCIGVPSAVPSGIRAVLAENLICSSLDLECASSNDQTFTHSDMRRTARLLMQFLPGTDFISSGYSAVPNYDNMFAGSNEDAEDFDDYNVIQRDLKVDGGLRPVREEDVIAIRNKAARALQAVFAGMGLPPITDEEVEAATYAHGSKDMPERNIVEDIKFAQEIINKNRNGLEVVKALAQGGFTDVAQDMLNIQKAKLTGDYLHTSAIIVGDGQVLSAVNDVNDYAGPATGYRLQGERWEEIKNIPGALDPNEID
What is the function of this protein?
The 1,2-PD-specific bacterial microcompartment (BMC) concentrates low levels of 1,2-PD catabolic enzymes, concentrates volatile reaction intermediates thus enhancing pathway flux and keeps the level of toxic, mutagenic propionaldehyde low.
What are the official names of this protein?
Propanediol dehydratase large subunit, Diol dehydratase large subunit, DDH large subunit, Propanediol utilization protein PduC.
What is the protein family that this protein belongs to?
Belongs to the diol/glycerol dehydratase large subunit family.
What are the subcellular locations of this protein?
Bacterial microcompartment. Note=Probably located inside the BMC shell.
Protein: TETM_NEIME
Sequence: MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLHLRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLRTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYTPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT
What is the function of this protein?
Abolishes the inhibitory effect of tetracyclin on protein synthesis by a non-covalent modification of the ribosomes.
What are the official names of this protein?
Tetracycline resistance protein TetM, Tet(M).
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. TetM/TetO subfamily.
Protein: PAK_DROME
Sequence: MSSEEDKPPAPPVRLTSNRGGNERSGGGVGVGGGGLGGGGMGDVPPDMRPLPKEPDDSDRKKKTLKSKIKGSKPSHTDSKPNISYPTNFEHTVHVGFDAVTGEFTGMPEAWARLLMNSNISKQEQKKNPQAVLDVLKWFDNTTKQRPSSKYMTNAITTHSGSSLSRVSSSSPSSTPTDSELHGSNSGGNLIGVQLGSMTLGPNANNVAVAGQILGNHYQQQQQHLLQQQQPLLHQNHNQHHMGISQSHSYNFVGHTVSSSTSQHSSANEDDMLGPQHPQQQPPPPPVASRPERTKSIYTRPIEDLQPAIIPMPVAPATTPATPLQNHRTPGGISAPAASPMMHNNATTTLDKNKNNANLYTPEPTVAQVSAGGPSSQVAGNQIAVPQAAVAPAATPNTRAANAKKKKMSDEEILEKLRTIVSVGDPNRKYTKMEKIGQGASGTVYTAIESSTGMEVAIKQMNLSQQPKKELIINEILVMRENKHPNVVNYLDSYLVSEELWVVMEYLPGGSLTDVVTETCMDEGQIAAVCREVLQALEFLHANQVIHRDIKSDNILLGLDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMVEGEPPYLNENPLKALYLIATNGKPEIKEKDKLSSAFQDFLDQCLEVEVDRRASALDLLKHPFLKLARPLASLTPLIMAAKEATKGN
What is the function of this protein?
Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes.  May be required for the formation of dendritic spines and excitatory synapses (By similarity).  During muscle embryogenesis, promotes proper muscle morphogenesis, as well as guidance and targeting of subsets of myotubes (PubMed:18996366).
What are the official names of this protein?
Serine/threonine-protein kinase Pak.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion.
Protein: CBIT_SULIN
Sequence: MEWKYVIPGIPDNFFERDEEIPMTKEEIRALALSKLRIRKGDMILDIGCGTGSVTVEASLLVGSTGKVYGVDKEEKAINLTRRNAEKFGVLNNIVLIKGEAPEILFTINEKFDRIFIGGGSEKIKEIISASWEIIKKGGRVVIDAILLETVNNAISAMENIGFINLEITEVIIAKGMKTKVGTAMMTRNPIFIISGEKQ
What is the function of this protein?
Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
What are the official names of this protein?
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating).
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Archaeal-type CbiT family.
Protein: RISB_POLSJ
Sequence: MFGAEKGSTDKLDGRKFSIGIVQARFNESVTNALAEACKQELAALGVEEKNIKHVKVPGALEVPCALQAMAESDKYDALIALGCIIRGETYHFELVANESGSAVTRLALDYQLPIANAILTTENLAQAEARQIEKGRDAARVAVEMANLLDELA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: LPXH_VIBCM
Sequence: MHTLFISDLHLSPKHPDITASFIQFMREEAIKADALYVLGDLFDFWIGDDDPTTFAEQIKSEFRQLTQQGVPCYFTKGNRDFLVGKRFAQQTGVQLLPDEAVIDLYGQKAVVLHGDTLCTQDTRYLEFRAKVHQPWLQRLFGLLPFALKQKLVRKIQSDIRDDKQHKSMMIMDVTPSEVIAVMHRYNVDLMIHGHTHRPAIHSIQTDDQTLKTRIVLGDWYSQSSILVYSKLTGYSLLSRPLINIE
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RSXC_SALA4
Sequence: MLKLFSAFRKDKIWDFDGGIHPPEMKTQSNGTPLRQVPLAPRFVIPLKQHIGAEGELCVSVGDRVLRGQALTRGRGRMLPVHAPTSGTVIAIAPHSTAHPSALAELSVIIDADGEDRWIEREGWSDYRAHSREALIERIHQYGVAGLGGAGFPTGVKLQGGGDKITTLIINAAECEPYITADDRLMQDCAAQIVEGIRILAHILQPREVLIGIEDNKPQAISMLRAVLADAHDISLRVIPTKYPSGGAKQLTQILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVVDGEPITERVVTLTGEAVSRPGNVWARLGTPVRHLLNDAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSVTEMGAPQEEKSCIRCSACADACPADLLPQQLYWFSKGQQHDKATAHHIADCIECGACAWVCPSNIPLVQYFRQEKAEINAIRLEEKRAAEAKARFEARQARLEREKAARLARHKSAAVQPAAKDQDAIAAALARVKEKQAQATQPVVIQAGSLPDNSAVIAAREARKAQARAKQAAHPVADSAISGGDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEAVDPRKAAVEAAIARAKARKQEQQAGGEPAEAVDPRKAAVEAAIARAKARKQEQQTGSEPAEPVDPRKAAVEAAIARAKARKQEQQTGSEPAEPADPRKAAVAAAIARVQAKKAAQQQVVNED
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rsx electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MENH_SALHS
Sequence: MMLHAQHMPGQPGAPSLVFLHGFSGDCREWQPVGEQFHGCSRLYIDLPGHGGSTAIPVGGFADVIRLLRATLISYNILKFWLVGYSLGGRVAMMAACQGIPGLCGLVVEGGHPGLQNEQARAERRLSDGRWAERFRREPLTEVFHDWYQQPVFASLTAQQRQTLTALRSQNNGETLAAMLEATSLAAQPDLREALNALAFPFYYLCGERDSKFRALAQEVAATCHVIRNAGHNAHRENPAGVVDSLAQILRL
What is the function of this protein?
Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
What are the official names of this protein?
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SHCHC synthase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MenH family.
Protein: NRDR_AFIC5
Sequence: MRCPSCGSLDTQVKDSRPTEDSSVIRRRRVCLTCNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVETERLEKMVSTIVRELESSGEAEISSEMIGEIVMENLRQLDDVAYVRFASVYRNFREAKDFETVLGELSDEGLPTNVRK
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: MTRB_BACVZ
Sequence: MNSKHSSDFVVIKAVEDGVNVIGLTRGTDTKFHHSEKLDKGEVIIAQFTEHTSAIKVRGNALIQTAYGEMNSEKK
What is the function of this protein?
Required for transcription attenuation control in the Trp operon.  This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination.  Binds the leader RNA only in presence of L-tryptophan.
What are the official names of this protein?
Transcription attenuation protein MtrB, Trp RNA-binding attenuation protein, TRAP, Tryptophan RNA-binding attenuator protein.
What is the protein family that this protein belongs to?
Belongs to the MtrB family.
Protein: RHLB_ECOSM
Sequence: MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHADAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLCAIQVVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEYIEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLTRPRTGNGPRRTGAPRNRRRSG
What is the function of this protein?
DEAD-box RNA helicase involved in RNA degradation.  Has RNA-dependent ATPase activity and unwinds double-stranded RNA.
What are the official names of this protein?
ATP-dependent RNA helicase RhlB.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. RhlB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_SYNWW
Sequence: MKTYVAKPAEVDRKWYVIDASDKTLGRLSSEVASILRGKHKPIFTPHVDTGDFVIVINAAKIKLTGDKLNQKKFRHHTGYPGGLREMDYRTLLQKRPEKAIEAAVQGMLPHNRLGRSMIKKLKVYSGSEHPHQAQKPELRELKG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: MURC_STAA3
Sequence: MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVILFMGAGDIQKLQNAYLDKLGMKNAF
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS1_ECOUT
Sequence: MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
What are the subcellular locations of this protein?
Cytoplasm.