PharMolix/UniProtQA huggingface dataset:
Protein: MT_CAIMO
Sequence: MDPQDCTCAAGDSCSCAGSCKCKNCRCRSCRKSCCSCCPAGCNNCAKGCVCKEPASSKCSCCH
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals.
What are the official names of this protein?
Metallothionein, MT.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 1 family.
Protein: GLPE_ENT38
Sequence: MDQFECINVEEAHQKMHQGKAVLVDIRDPQSYAMGHTPGAFHLTNDTLGTFMRDNDFETPVMVMCYHGNSSKGAAQYLLQQGYDAVYSVDGGFDAWHRHFPAEVEHAFGG
What is the function of this protein?
Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
What are the official names of this protein?
Thiosulfate sulfurtransferase GlpE.
What is the protein family that this protein belongs to?
Belongs to the GlpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RASG_DICDI
Sequence: MTEYKLVIVGGGGVGKSALTIQLIQNHFIDEYDPTIEDSYRKQVTIDEETCLLDILDTAGQEEYSAMRDQYMRTGQGFLCVYSITSRSSFDEIASFREQILRVKDKDRVPMIVVGNKCDLESDRQVTTGEGQDLAKSFGSPFLETSAKIRVNVEEAFYSLVREIRKDLKGDSKPEKGKKKRPLKACTLL
What is the function of this protein?
Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
What are the official names of this protein?
Ras-like protein rasG.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: CYF_CAPBU
Sequence: MQTRNTFSWIREEITRSISVSLMIYIITWASISGAYPIFAQQNYENPREATGRIVCANCHLANKPVDIEVPQTVLPDTVFEAVVKIPYDMQLKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEMKEKIGNLSFQNYRPNKKNILVIGPVPGQKYSEITFPILAPDPATNKDVHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATAGGIISKILRKEKGGYEITIVDASNGREVIDIIPRGLELLVSEGESIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFLGSVVLAQIFLVLKKKQFEKVQLSEMNF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome f.
What is the protein family that this protein belongs to?
Belongs to the cytochrome f family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: HSBP1_MOUSE
Sequence: MAETDPKTMQDITLVVETLLQQMQDKFQIMSDQIIGRIDDMSSRIDDLEKNIADLMTQAGVEELDPENKIPTAQKS
What is the function of this protein?
Negative regulator of the heat shock response.  Negatively affects HSF1 DNA-binding activity.  May have a role in the suppression of the activation of the stress response during the aging process (By similarity).
What are the official names of this protein?
Heat shock factor-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the HSBP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KTHY_NITHX
Sequence: MTEAAPKVGLLRGRFITFEGGEGSGKSTQINILAERLNAAKLRAIVTREPGGSPGAEIIRHLVLSGMGKLLGAYAETLLFAAARDDHVHTVIKPALEQGIWVLCDRFADSTRAYQGRLGDVLPGVLNALERVTIGDLKPDLTVILDVPVEIGMQRAAVRRGSGAPDRFEAEDVAFHQKLRDAYRDIAASDPQRCVVIDANADVNTVAAGVWAALRDRVLVADSSTKVTRA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: PUR5_PSEA8
Sequence: MSSKQPSLSYKDAGVDIDAGEALVERIKGVAKRTARPEVMGGLGGFGALCEIPAGYKQPVLVSGTDGVGTKLRLALNLNKHDSIGQDLVAMCVNDLVVCGAEPLFFLDYYATGKLNVDVAATVVTGIGAGCELAGCSLVGGETAEMPGMYEGEDYDLAGFCVGVVEKAEIIDGSRVQAGDALIALPSSGPHSNGYSLIRKIIEVSGADIEQVQLDGKPLADLLMAPTRIYVKPLLQLIKQTGAVKAMAHITGGGLLDNIPRVLPDNAQAVIDVASWNRPAVFDWLQEQGNVDETEMHRVLNCGVGMVICVAQSDAEKALEVLRAAGEQPWQIGRIETCGADAERVVLNNLKNH
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SSRD_BOVIN
Sequence: MAALASLGALALLLLSGLSCCSEACVEPQITPSYYTTSDAVISTETVFIVEISLTCKNRVQNMALYADVSGKQFPVTRGQDVGRYQVSWSLDHKSAHAGTYEVRFFDEESYSLLRKAQRNNEDVSVIPPLFTVSVDHRGTWNGPWVSTEVLAAAIGLVIYYLAFSAKSHIQA
What is the function of this protein?
TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
What are the official names of this protein?
Translocon-associated protein subunit delta, TRAP-delta, Signal sequence receptor subunit delta, SSR-delta.
What is the protein family that this protein belongs to?
Belongs to the TRAP-delta family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: FABH_ROSDO
Sequence: MTLRAVVTGVGHYLPDRIVPNSEFEKTLDTNDEWIRARSGIERRHFAAEGETTASMAAAASRAALSMAGAEAQDVDAIIVATSTADLTFPSAATMVQAELGMTRGFAFDVQAVCAGFVFALSNANALILSGQARRVLVIGAEAFSRIMDWTDRSTCVLFGDGAGAVLLEAQDGTGTSADRGILSTDLNSDGRHKDLLYVDGGVSTGTTGYLRMQGNQVFRHAVEKLAATATTALERAGVSASDVDWVVPHQANIRIIQGTAKKLGVSMDRVVVTVQDHGNTSAASIPLALSVGHARGQIKQGDLVVTEAIGGGLAWGAVVLRW
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_DECAR
Sequence: MQFELNAQARTLQGTGASRRLRHAAKVPGIVYGGAAAPQSIEVDHNDLLLKLKKEAFHSSIINLIIDGKKEQVLLRDTQVHAYKPLVLHVDFQRVDATHELHVKVPLHFVNEEVAPGVKLNGGLVNHVMTEVDIQCLAGDLPEFIEVDLSSLKIGGSIHLSQLKLPKGVKIVHHTADDSVVVGIVGKGGASEEAAEGEAAAAE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: COPB_DANRE
Sequence: MTAAENVCYTLINVTNDSEPPSEVSLKTDLEKGEIKAKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGKLLQEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKESELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVHTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPTHERVLQDLVMDILRVLTTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVTEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDTNEAAAADVLEFVREAIQRFDNLRPLIIEKMLEVFHAIKTVKIYRGALWILGEYCSTKEDIQSVMTEVRRSLGEIPIVENELKKEAGEVKPEEEVTAAPAPKLVTEMGTYVTQSALSTSRPSKKEEDRPPLRGFLMDGDFYVAASLATTLTKVALRYVALAEDKRRQNSFVAEAMLIMATVLHLGKSSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRRSLSHMLAVRLEEEKLSQKKESEKRNVTVQADDPISFMQLTAKNEMASKEDQFQLSLLAAMGNTQRKEATDPLASKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPASCTDAEFRQMWAEFEWENKVTVNTNITDLNDYLLHILKSTNMKCLTPEKALSGICGFMAANLYARSIFGEDALANVSIEKPIHLGVDAPVNGHIRIRAKSQGMALSLGDKINLSQKRTAS
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity).
What are the official names of this protein?
Coatomer subunit beta, Beta-coat protein, Beta-COP.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
Protein: CHS1_SINAL
Sequence: MVMGTPSSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKDNPNMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDADISAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDDVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSVEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
What is the function of this protein?
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
What are the official names of this protein?
Chalcone synthase 1, Naringenin-chalcone synthase 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.
Protein: RBL_VANST
Sequence: NYYTPDYETKGTDILAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEEHQFIAYVAYPLDLFEEGSVTNLFTSIVGNVFGFKALRALRLGDLRIPPSYSKTFMGPPHGIQVERDKLNKYGRPFLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKAQSETGEVKGHYLNATAGTCEEMFKRAIFARELGAPIVMHDYLTGGFTANTSLAYYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHFHSGTVVGKLEGERDITLGFVDLLRDDYIDKDRSRGIYFTQDWVSMPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALVACV
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site (By similarity).
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CH60_SALPB
Sequence: MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQSIITEGLKAVAAGMNPMDLKRGIDKAVAAAVEELKALSVPCSDSKAIAQVGTISANSDETVGKLIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALIRVASKIADLKGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKSDAPDLGAAGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_BIFLO
Sequence: MSDFVDRVTVHVKGGDGGNGSAGIRREKYKPLAGPNGGNGGDGGSVVFVADRNATSLLDYRFMPHRVAGSGTMGLGDNKDGSKGEDLILPVPCGTVVFEARGEQGKAKHPGAQLADLRHEGDRCVVAQGGAGGLGNIALANKTRRAPGFALLGELGEERDVILELKSIADVALVGFPSAGKSSLIAAMSSAKPKIADYPFTTLVPNLGVVIAGDSRYTIADVPGLIPGASEGKGLGLEFLRHIERTEIIAHVIDCATLEPDRDPMSDYHALENELALYADKLELPLGAIPIPERPRIVILNKIDVPEAKELAEFVRPEFEKLGLKVFEISTASHEGLKELNFALSALVHEMREEVANREQAEEEARVVIKPLETKGRRPRRADEGGSALEFTVERRELGNGEVFFEVRGVKPERWVMQTNFDNDEAVGYLADRLAKLGVEDELRRKGAHPGDEVRIGRGARMVEFDWDPTISAGAEMLDGSNLGARGKDLRLEELDPRTHRRSNAERRAQYHEMMDARAAVRDAMMAERKAGHWADPTVDDDRHDETSLFGHGESSEDGETEE
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_ECO55
Sequence: MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMRVASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGASAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRERAQILADEVGAEVIALSEIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLLVDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMAWLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAPTKSLQQAARDGDNERLNILRDSLGLE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: YFAA_ECOLI
Sequence: MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIAGDLLSGKKRWQASFGLEERTAEKTPVRQRIVVSARWLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGIAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
What are the official names of this protein?
Uncharacterized protein YfaA.
Protein: DUT_SALHS
Sequence: MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: MURA1_STAS1
Sequence: MAQEVIKIRGGQTLKGEVNNHGAKNSAVAIIPAAILAEDKVTIEGLPEISDVETLVSLLGDLNIKTELDGMTLNVDPNEIENAPLPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAKIDESSSTSMKIEADKLTGANIFLDIVSVGATINIMLAAVRAEGQTVIENAAKEPEVVDVANFLTSLGADIKGAGTSTIKINGVEHLHGSHHQVIPDRIEAGTYMCIAAACGEDITINNIIPTHVEPLTVKLKELGVDIQVGDDSAVIQRSTPYASVDIKTLVYPGFATDLQQPITPLLFMADGVSFVTETIYPARFRHVDELKNMGADISADNGTATIKPSKLTGAEVYASDLRAGACLIVAGLLAEGVTTIYNVKHIYRGYTNIVSTLKSLGADIWTEEV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DKSA_ECOL6
Sequence: MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRILEAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG
What is the function of this protein?
Transcription factor that acts by binding directly to the RNA polymerase (RNAP).  Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters.  Also required for regulation of fis expression.
What are the official names of this protein?
RNA polymerase-binding transcription factor DksA.
What is the protein family that this protein belongs to?
Belongs to the DksA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOD_XANC8
Sequence: MSEYRQATDAFASNPVESKQEIRNYTMNFGPQHPAAHGVLRLILEMDGETVVRADPHIGLLHRGTEKLAESKPFNQSVPYMDRLDYVSMMCNEHAYVRAIESLMGIEAPERAQYIRTMFDEITRIKNHLMWVGSNALDLGAMAVMLYAFREREELMDVYEAVSGARMHAAYYRPGGVYRDLPDRMPKYKESRWHKGGALTKLNAAREGSMLDFLENFTDTFPSRVDEYETLLTENRIWKQRTVDVGIISPDLARAWGMTGPMLRGSGIEWDLRKKQPYAKYDAVDFDVPVGTNGDCYDRYLVRVAEMRESNRIIKQCVKWLKANPGPVMVTNFKVAPPSREGMKDDMEALIHHFKLFSEGYCVPAGETYCAVEAPKGEFGCYLMSDGANKPFRVHLRAPGFAHLSSMDAVVRGYLLADVVAMIGTYDLVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ATPF2_GLUOX
Sequence: MTVDWWTIGLQVINVSVLIWLLSRFFWRPICAVISRRQQEIAAQLAQVTDGQKQLEADRAAVKEARSSFEQERARIVQQAQQEAQSERQAILAKAQQDAAALEAGAKQSIAQEEAENQARWRSDAAALSCDIAGQLLAQTGCCRPARETLFDRLLKAIATLPDRERLSLRDGFTFATATAPSPDERQAYESALMTAVGEHPVITWAVDPALVEGFAVKTPYLTVASNWQADLVRIREGLSHAGH
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 2, ATP synthase F(0) sector subunit b 2, ATPase subunit I 2, F-type ATPase subunit b 2, F-ATPase subunit b 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: GPI13_YEAST
Sequence: MDEKTIKKSILSSSNDEKIIYKSRIKKFQKNHKFYIILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFAIPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEIARNDREWSQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKYQKVFLQTCEELWAKFDYYSIATGITLLATSLVLLISITKLIPSIVVNQMVPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMRLGETLADYWSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKRQSTTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGGYHSAVLIIFTRLASMITICREEQGEYCIPTFNNQNNSSWWVLGLCFLMIFILPACITGYYNLTSSYQAAAPIWINVFLKGILGLNFVYWSLTSLENNSAVIAIPFLRDVTIFKFTLARIIAGFSLIASNVGWLMGPLCIKLNIHNTDVKSHEATILGYTNIYGSEFFLLVINVLISILLFNKPLAQLSYFLMCNQLLSILEIIDLLKLKENIIGPIALGLLSYQHFFTTGHQATIPSVQWDIGFMLSEKVTFPFTQIAIILNTFGPHILVSLSVALLTLWSQPPDVLKPQTLLGRIVSNCGILLTYNTILCLSSFIWVTHFRRHLMVWKIFCPRFIFASLSLIVTQLVVTFGTIAFASGRLIKHINDIFWK
What is the function of this protein?
Involved in glycosylphosphatidylinositol-anchor biosynthesis.  Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.  Involved in cell wall biosynthesis.
What are the official names of this protein?
GPI ethanolamine phosphate transferase 3, Glycosylphosphatidylinositol-anchor biosynthesis protein 13.
What is the protein family that this protein belongs to?
Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL34_THEFY
Sequence: MSKRTYQPNNRRRARTHGFRLRMRTRAGRAIIAARRRKGRKALTVSH
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: EI2BB_DICDI
Sequence: MEKQAEKQLEKQLESFILHLKRKTVVGSYQVSRASAELLRQWVHKGKWGNAKSLIDQIKIIGKKLMNAQPLEFCIGNIVRRVLFIIREEYLTFFRNKKNGLNNDDYDDDDFETTTSNNNNNNNNNNINSSSNINKNNKYSNVMLQDDPIDDQEDIDFTETFPRLKAAIMDSINELIDELEGLHRNVAEQAIEHIHSNETIMTLGCSRTVEEFLKEAARKRSFKVIVVETAPSLEGQKTAISLSKASIDTTLITDSAVFAMMSRVNKVIIGTHAVMANGGLIATSGTHTLAVAAKYHSVPIVVCTGLYKLCPLYAYDQDTFNNFGSPGEYLKFEEAEFLENVHSYNPTFDYVAPDLVSLFITNIGGHNPSYIYRLLQEYYDARDILEDE
What is the function of this protein?
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
What are the official names of this protein?
Translation initiation factor eIF-2B subunit beta, eIF-2B GDP-GTP exchange factor subunit beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family.
Protein: LRP8_CHICK
Sequence: MCRPALARLLLLQLLLLKLYLGKGAMKECDKDQFQCRNERCIPAVWACDEDNDCSDNSDEADCPKKTCAETDFACDNGHCIPDRWKCDGEEECSDGSDESEAACTKQVCPAEKISCGDLSNKCIPSSWRCDGQKDCESGIDEAGCAPACSPDEFQCSNKTCISINFVCDGYNNCGDGSDEKKCSPLTCSPNEFQCNNSVCIPQLWVCDNQADCEDHSDESIERCGYDAKAFNTCAAHEFQCGNGECILLNWKCDGDEDCKDKSDEQDCPLVTCRPDEFQCGDGTCIHGAKQCDKVHDCPDNSDEAGCVQESACESPSKFQCKSGECIDGGKVCDLHRDCRDWSDEPLKECGINECSLNNGGCSHICKDLKIGYECECPPGYKLLDKKTCGDIDECENPDACSQICINYKGDYKCECYEGYEMDTLSKNCKAVGKSPYLIFTNRHEVRKIDLVKRDYSRIIPMLKNVVALDVEVATNRIYWCDLFYRKIYSAYIDKASDTAEQVILIDSQLNSPEGVAIDWVHKNIYWTDSGNKTISVATADGSRRRTVFNSDLSEPRAIAVDPTRRFMYWSDWGDKAKIEKAGLNGVGRQVLVSDNIEWPNGITLDLLNQRLYWVDSKLHSLSCIDFNGSNREVLISSIDDLSHPFGLAVFEDRVFWTDLENEAIFSANRLSGLDISVLAENLNNPHDIVVFHELKQPKAPDSCELSPQPNGGCEYLCLPAPHISPRSPKFTCACPDNMWLGPDMKKCYKELPTTPATVEVPTTTTSHPAATSTVTVTGSANTTTAVIPRAVSEATTAIPSSHSTTSLLIDSEMTTGNSNLSQHYSNNGQGFDSTVTAAVIGIVIPVVVIGLLCMGGYLIWRNWKRKNTKSMNFDNPVYRKTTEEEDEDEIHIGRTAQIGHVYPARVALSLEDDGLP
What is the function of this protein?
Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands.  Also binds alpha2-macroglobulin.  LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail.  Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons.  LRP8 has higher affinity for Reelin than VLDLR.  LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development.  Not required for endocytic uptake of SEPP1 in the kidney which is mediated by LRP2 (By similarity).
What are the official names of this protein?
Low-density lipoprotein receptor-related protein 8, LRP-8, Apolipoprotein E receptor 2, Protein LR8B.
What is the protein family that this protein belongs to?
Belongs to the LDLR family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: DCD_SALCH
Sequence: MRLCDRDIEAWLDEGRLSITPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLPDGEAFYLHPGELALAVTFESVTLPPDLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.