PharMolix/UniProtQA huggingface dataset:
Protein: GLYR1_HUMAN
Sequence: MAAVSLRLGDLVWGKLGRYPPWPGKIVNPPKDLKKPRGKKCFFVKFFGTEDHAWIKVEQLKPYHAHKEEMIKINKGKRFQQAVDAVEEFLRRAKGKDQTSSHNSSDDKNRRNSSEERSRPNSGDEKRKLSLSEGKVKKNMGEGKKRVSSGSSERGSKSPLKRAQEQSPRKRGRPPKDEKDLTIPESSTVKGMMAGPMAAFKWQPTASEPVKDADPHFHHFLLSQTEKPAVCYQAITKKLKICEEETGSTSIQAADSTAVNGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQQTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVYRAYIH
What is the function of this protein?
Cytokine-like nuclear factor with chromatin gene reader activity involved in chromatin modification and regulation of gene expression (PubMed:23260659, PubMed:30970244).  Acts as a nucleosome-destabilizing factor that is recruited to genes during transcriptional activation (PubMed:30970244, PubMed:29759984).  Recognizes and binds histone H3 without a preference for specific epigenetic markers and also binds DNA (PubMed:20850016, PubMed:30970244).  Interacts with KDM1B and promotes its histone demethylase activity by facilitating the capture of H3 tails, they form a multifunctional enzyme complex that modifies transcribed chromatin and facilitates Pol II transcription through nucleosomes (PubMed:23260659, PubMed:30970244, PubMed:29759984).  Stimulates the acetylation of 'Lys-56' of nucleosomal histone H3 (H3K56ac) by EP300 (PubMed:29759984).  With GATA4, co-binds a defined set of heart development genes and coregulates their expression during cardiomyocyte differentiation (PubMed:35182466).  Regulates p38 MAP kinase activity by mediating stress activation of MAPK14/p38alpha and specifically regulating MAPK14 signaling (PubMed:16352664).  Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664).  The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664).
What are the official names of this protein?
Cytokine-like nuclear factor N-PAC, NPAC, 3-hydroxyisobutyrate dehydrogenase-like protein, Glyoxylate reductase 1 homolog, Nuclear protein NP60, Nuclear protein of 60 kDa, Nucleosome-destabilizing factor, hNDF, Putative oxidoreductase GLYR1.
What is the protein family that this protein belongs to?
Belongs to the HIBADH-related family. NP60 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Found in actively RNAPolII-transcribed gene bodies.
Protein: MEND_CYTH3
Sequence: MQAIYDIPEILFQHGVTDVVLSPGSRCAPLSIAFSRHKKLQIKVVPDERSAAFIALGMSLQTQKPTVLICTSGSALYNYAPAIVEAYYQRVPLIVLSADRPPEWIDQNDGQTIRQQEIYGKHSKAFFQLSAEHELPDTQWETYRKVNEAVSISEAYPKGPVHINIPFREPFYPKGEIMFSGSPTVIKREQPLHTLSDEQWKSIQHKLDSYKKILFVGGQHLYDESLRLKIGNIKAPFIGEVVSNLHGVRNVIHTHDTLLTSIPLTDLEELKPDLVISFGGALLSKWLKQFIRSNESIDHWYVGPDVTTPDVFQHLCQIIPVQLNEFLSKTTIASNTQEQFVQRWIQQQTHIIPAIREFNTKEKVFNEFTAVFDVLNHLPAFAKLHLANSMSVRYANTLGISQRNAEVFANRGTSGIDGVISTAYGYALKTSQLVTIITGDLAFFYDRNAFWNNYKPSNLRVVLLNNHGGGIFRMIDGPSALPELDELFETKQTLSARYLATEHGLEYTLCKNLNGLNQALESFFQPSMFGKILEIETDSVKNTEVFKRFKKTIQQSYLS
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: GBP4_MOUSE
Sequence: MTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGWSHTGKSYLMNCLAGQNHVSGTLPTSQRFPSGLHRAVSDQGHLDVVHAPPHQARALVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFVYNSMNTINHQALEQLHYVTELTELIRAKSSPNPHGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDEYLENALKLIPGNNPRIQASNSARECIRRFFPNRKCFVFEWPTHDIELIKQLETISEDQLDPTFKESAMAFASYIFTYAKIKTLREGIKVTGNGLGTLVTTYVDAINSGAVPCLDDAVTTLAQRENSVAVQKAASHYSEQMAQRLSLPTDTIQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELLREKNGLFLLKNEEASDKYCQEELDRLSKDLMDNISTFSVPGGHRLYMDMREKIEHDYWQVPRKGVKASEVFQNFLQSQAIIESSILQADTALTAGQKAIAEKHTKKEAAEKEQDLLRQKQKEHQEYMEAQEKRNKENLEQLRRKLEQEREQLIKDHNMMLEKLTKEQKTFREEGYKTQAEELRREIHQLGHNIKEMKQNGDSLVESILRSWFSFISPPSESEKAISSVLSLLRKKDRL
What is the function of this protein?
Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens (PubMed:18025219).  Negatively regulates the antiviral response by inhibiting activation of IRF7 transcription factor (PubMed:22095711).
What are the official names of this protein?
Guanylate-binding protein 4, GTP-binding protein 4, GBP-4, Guanine nucleotide-binding protein 4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Golgi apparatus membrane. Note=Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus.
Protein: Y9240_DICDI
Sequence: MEKNYIFENSIYKDENENDNEDDQYYNNNSSNNDEIINEEYLIKKREKIETLFLYQNFQIVITELINLLYKLYSNNNNNNNNNSPLLSSIFNTNNEENNENPTTTTISLSNKIFESFSKCYHSCQNDTNCQCRWIMELLIQSLYEVGKPSDALKLVNRFYQDGISNTPINILILSIHLLVYLKSYNESKVIIIEALKRNRNEFKSDQYEQLIELLIFHVMFRMNEINESISLLQNDSYLSDWKKNGFIKALYEMVQIREFEEKNQRELQLKRETEKLQQQNQQQQQQQLEKQLINEQQQHQQQQELNNSSQPQQEQEQLPIKTQSNISIIKDIINESIHEILSIRDLKSLKLAINRVLFAVKRVSNSRNNNNNNNNNNNNLINTKTLKQQQQQKLNSNNKRQFGIKNVQQQQQQPYRNSQQYQQYRQNNRSILNSNNNNNNNNSSTANWGGLKQLLSNTFSFNRV
What are the official names of this protein?
Putative uncharacterized protein DDB_G0287573.
Protein: TRP4_PYRAP
Sequence: TPASGFFGMR
What are the official names of this protein?
Tachykinin-related peptide 4, TKRP-4.
What are the subcellular locations of this protein?
Secreted.
Protein: BACD3_HUMAN
Sequence: MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRIHIKRPDDRAHLHQ
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex.  The BCR(BACURD3) E3 ubiquitin ligase complex mediates the ubiquitination of target proteins, leading to their degradation by the proteasome (By similarity).
What are the official names of this protein?
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3, hBACURD3, BTB/POZ domain-containing protein KCTD10, Potassium channel tetramerization domain-containing protein 10.
What is the protein family that this protein belongs to?
Belongs to the BACURD family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PURA_HELPG
Sequence: MADVVVGIQWGDEGKGKIVDRIAKDYDFVVRYQGGHNAGHTIVHKGVKHSLHLMPSGVLYPKCKNIISSAVVVSVKDLCEEISAFEDLENRLFVSDRAHVILPYHAKKDAFKEKSQNIGTTKKGIGPCYEDKMARSGIRMGDLLDDKILEEKLNAHFKAIEPFKEAYGLGENYEKDLREYFKTYAKKICPFIKDTTSMLIEANQKGEKILLEGAQGTLLDIDLGTYPFVTSSNTTSASACVSTGLNPKAINEVIGITKAYSTRVGNGPFPSEDATPMGDHLRTKGAEFGTTTKRPRRCGWLDLVALKYACALNGCTQLALMKLDVLDGIDAIKVCVAYERKGERLEAFPSDLKDCMPIYQTFKGWEKSVGVRKLEDLEPNAREYVRFIEKEVGVKIGLISTSPEREDTIFL
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_LEPIC
Sequence: MSNLTARVIPCLDIKDGRVVKGVNFVNLVDAGDPVESAAIYEENLADELCFLDITASSDRREILLHLVERIAEKIFIPFTVGGGIRTVDDVKAVLEKGADKVSINTAAFQNPKLLTYSSEIYGSQCIVCAIDVKHEKERDRYEVFLHGGRTATGREALDWAQEAAEKGAGEILLTSMDRDGTRNGFDIHLLKNFSSSLGIPIIASGGAGNPEHMVEAILRGKADAVLAASIFHFGEYSIRETKKAMEEMGISVRLD
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUL5_HUMAN
Sequence: MATSNLLKNKGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHAVCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTALLKAYIVEWRKFFTQCDILPKPFCQLEITLMGKQGSNKKSNVEDSIVRKLMLDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIGVRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAPSYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVEALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSLMDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEKYVEQLLTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVNDATIFKLELPLKQKGVGLKTQPESKCPELLANYCDMLLRKTPLSKKLTSEEIEAKLKEVLLVLKYVQNKDVFMRYHKAHLTRRLILDISADSEIEENMVEWLREVGMPADYVNKLARMFQDIKVSEDLNQAFKEMHKNNKLALPADSVNIKILNAGAWSRSSEKVFVSLPTELEDLIPEVEEFYKKNHSGRKLHWHHLMSNGIITFKNEVGQYDLEVTTFQLAVLFAWNQRPREKISFENLKLATELPDAELRRTLWSLVAFPKLKRQVLLYEPQVNSPKDFTEGTLFSVNQEFSLIKNAKVQKRGKINLIGRLQLTTERMREEENEGIVQLRILRTQEAIIQIMKMRKKISNAQLQTELVEILKNMFLPQKKMIKEQIEWLIEHKYIRRDESDINTFIYMA
What is the function of this protein?
(Microbial infection) Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein.
What are the official names of this protein?
Cullin-5, CUL-5, Vasopressin-activated calcium-mobilizing receptor 1, VACM-1.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: YQGF_ECOK1
Sequence: MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNIIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1489_CARHZ
Sequence: MEIKFINIGFGNIVSANRIISIVSPESAPIKRIISEARDKGMLIDATYGRRTRAVIIMDSDHVILSAVQPETVAHRLNTKENQEENF
What are the official names of this protein?
Putative regulatory protein CHY_1489.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: KAD_STAAN
Sequence: MNIILMGLPGAGKGTQASEIVKKFPIPHISTGDMFRKAIKEETELGKEAKSYMDRGELVPDEVTVGIVKERISEDDAKKGFLLDGFPRTIEQAEALNNIMSELDRNIDAVINIEVPEEELMNRLTGRRICESCGTTYHLVFNPPKVEGICDIDGGKLYQREDDNPETVANRLSVNIKQSKPILDFYDQKGVLKNIDGSKDISDVTKDVIDILDHL
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_NITOC
Sequence: MLLWPAPAKLNLFLHIIGRREDGYHLLQTAFQFVDYCDWLEFRPSADGRIEHLSPLPGVPVEHDLVYRAALLLQQRTACSQGVEVRIRKHLPMGGGLGGGSSDAATTLVALNHLWETGLSISQLAQLGLELGADVPVFIYGRAAWAEGVGEQLQPLELPEPWYLIVTPAVQVSTREVFIAPELTRDCKPMTISGLLAGEGENVCEPVVRGLYPVVADALDWLSQFSPARMTGTGSSIFAAFDGKSQALAALACMPSHWQGIVAKGCNYSLLLDCLEKTGC
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RSMH_CLOBA
Sequence: MEFKHISVLLNECLDALDIKDNGIYVDCTLGGAGHSSHILERLSNEGLLIGIDQDRDALKAAKERLKRFENVKYVHSNFYDIDNILQNLDIPKVDGILMDLGVSSYQLDEGARGFSYMKDAPLDMRMNRDNDFSAYEIVNEYSEDELYKIIRNYGEERFAKRISNCIVNRRSDKPIETTMELVDIIKAAIPAKARREGPHPAKRTFQAIRIEVNSELKILNQTIEDGVNRLKPGGRMAIITFHSLEDRIVKLKFRELNDPCTCPREFPMCICGKKPSVRLVSRKGIEPTKEEVEENPRSRSAKLRIIEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCR2_MOUSE
Sequence: MKLLSRAGSFSRFYSLKVAPKVKTSAAPGGVPLQPQDLEFTKLPNGLVIASLENYAPLSRIGLFVKAGSRYEDSNNLGTSHLLRLASSLTTKGASSFKITRGIEAVGGKLSVTATRENMAYTVEGIRSDIEILMEFLLNVTTAPEFRRWEVAALRSQLKIDKAVAFQNSQTRIIENLHDVAYKNALANPLYCPDYRMGKITSEELHYFVQNHFTSARMALVGLGVSHSVLKQVAEQFLNMRGGLGLAGAKAKYRGGEIREQNGDNLVHAAIVAESAAIGNAEANAFSVLQHLLGAGPHIKRGNNTTSLLSQSVAKGSHQPFDVSAFNASYSDSGLFGIYTISQAAAAGEVINAAYNQVKAVAQGNLSSADVQAAKNKLKAGYLMSVETSEGFLSEIGSQALAAGSYMPPSTVLQQIDSVADADVVKAAKKFVSGKKSMAASGNLGHTPFLDEL
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c (By similarity).  The 2 core subunits UQCRC1/QCR1 and UQCRC2/QCR2 are homologous to the 2 mitochondrial-processing peptidase (MPP) subunits beta-MPP and alpha-MPP respectively, and they seem to have preserved their MPP processing properties.  May be involved in the in situ processing of UQCRFS1 into the mature Rieske protein and its mitochondrial targeting sequence (MTS)/subunit 9 when incorporated into complex III (By similarity).
What are the official names of this protein?
Cytochrome b-c1 complex subunit 2, mitochondrial, Complex III subunit 2, Core protein II, Ubiquinol-cytochrome-c reductase complex core protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RS8_HYDCU
Sequence: MSMSDPIADMLTRIRNGQIAGHSNVVMPSSKVKVAVAKVLTGEGYVSSYSVSDKNGKSELSVDLKYFEGQPVIEMLKRVSRPGLRVYKNKDELPKVIGGLGVAVVSTSKGIMSDRDARKAGIGGEIICYIA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: CLPP_SULDN
Sequence: MSYIPYVVEKTARGERSYDIYSRLLKDRIIMLSGEVNDAVASSIVAQMLFLEAEDPEKDIYFYINSPGGVVTAGMAIYDTMNYIRPDVATICVGQAASMGAFLLSSGAKGKRYALPHARIMIHQPLGGAQGQATDIAIQAKEILRMKEELNAILAKNCSQSIKKVEKDTDRDNFMSAEESKEYGMIDEVLLKKSKE
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BRDOS_HUMAN
Sequence: MSGRVPLAEKALSEGYARLRYRDTSLLIWQQQQQKLESVPPGTYLSRSRSMWYSQYGNEAILVRDKNKLEVSRDTGQSKFCTIM
What are the official names of this protein?
Putative uncharacterized protein BRD3OS, BRD3 opposite strand protein, Long intergenic non-protein coding RNA 94, Non-protein coding RNA 94.
Protein: DNJC3_CHICK
Sequence: MVSAAASAGRLGSALPFLLVLLDLQYQGAECGINAEVEKQLEMGKKLLAAGQLADALSHFHAAIEGDSDNYIAYYRRATVYLAMGKSKAAIRDLSKVVELKQDFTSRLQRGHLLLKQGKFDEAEDDFKNVLKSNPSNNEEKEAQTQLTKSDELQRLYSQALSAYRQEDYEAAIPLLDEILAVCVWDAELRELRAECYIKEGEPSKAISDLKAAAKLKSDNTEAFYKISRIYYQLGDHELSLSEVRECLKLDQDHKQCFSLYKQVKKLNKQIESAEEFIREGRYEDAISKYDSVMKTEPDVPVYATRAKERICHCLSKNQQATEAITVCTQVLQLEPTNVNALKDRAEAYLLEDLYEEAIKDYETAQANSENDQQIREGLERAQRMLKQSQKRDYYKILGVKRNARKQEIIKAYRKLASQWHPDNFQSEEEKKKAEKKFIDIAAAKEVLTDPEMRRKFDAGEDPLDAESQQGGGNPFHRNWNTWQGFNPFGSGGGPFTFKFHFS
What is the function of this protein?
May be involved in the unfolded protein response (UPR) during ER stress.
What are the official names of this protein?
DnaJ homolog subfamily C member 3.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: ISPT_BORBR
Sequence: MALSSTQAIPETGDIPRHVAIIMDGNGRWATRRHLPRTAGHAKGVHAVRRVVEACGRRGVRYLTLFAFSSENWRRPADEVSLLMRLFVQALEREVDKLQDQGVRLHVVGDLSAFEPKLQELIAQAQERTEHNDRLHLTVAANYGGRWDILQATRAMLRADPGLAQDPDRIDEARLAEHLSMAWAPEPDLFIRTGGEQRISNFLVWQLAYAEFYFTEQFWPDFGADELDAAFEWYRTRERRFGRTSAQLRGGAKR
What is the function of this protein?
Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
What are the official names of this protein?
Isoprenyl transferase.
What is the protein family that this protein belongs to?
Belongs to the UPP synthase family.
Protein: LEPA_NITHX
Sequence: MSDELRKRGTTPIANIRNFSIVAHIDHGKSTLADRLIQMTGGLSDREMAGKEQVLDSMDIERERGITIKAQTVRLNYHAKDGKDYIFNLMDTPGHVDFAYEVSRSLAACEGSLLVVDASQGVEAQTLANVYQALDNNHEIVPVLNKVDLPAAEPDKVKQQIEDVIGIDASDAVMISAKTGLGVPDVLEAIVTRLPPPQGDRDATLKALLVDSWYDVYLGVVVLVRIVDGVMKKNSRIRMMGTNAAYDVERVGFFTPKMQQVDELGPGEIGFITAAIKEVADTRVGDTITDDRKPITEMLPGFKPAIPVVFCGLFPVDADDFETLRTAMGKLRLNDASFSFEMETSAALGFGFRCGFLGLLHLEIIQERLSREFDLNLIATAPSVIYKMKLTDGGEIEIHNPIDMPDVVKIAEIAEPWIEATILTPDDYLGSVLKLCQERRGSQKELTYVGSRAMVRYDLPLNEVVFDFYDRLKSVSKGYASFDYHLTDYKVADLVKMQILVNGEPVDALSMLVHRTRAEGRGRAMVEKMKELIPPHMFQIPIQAAIGGKVIARETVRALRKDVTAKCYGGDITRKRKLLEKQKEGKKKMRQFGKVDIPQEAFIAALKVDG
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KDSA_SALG2
Sequence: MKQKVVNIGDIKVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGNDKVILCDRGANFGYDNLVVDMLGFSVMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRGQVTELARAGMAVGLAGLFLESHPDPANAKCDGPSALPLAKLEQFLTQIKAIDDLVKSFDELDTEN
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLP3B_ARATH
Sequence: MDPDTVKSTLSNLAFGNVLAAAARDYKKEVLANEKAQGSRPVNEEVDLDELMDDPELEKLHADRIAALRREVEKREAFKRQGHGEYREVSEGDFLGEVTRSEKVICHFYHKEFYRCKIMDKHLKTLAPRHVDTKFIKMDAENAPFFVTKLAIKTLPCVILFSKGIAMDRLVGFQDLGAKDDFSTTKLENLLVKKGMLSEKRKEEDEEDYEYQESIRRSVRSSANVDSDSD
What is the function of this protein?
Tubulin-binding protein involved in microtubule formation.
What are the official names of this protein?
Thioredoxin domain-containing protein PLP3B, Phosducin-like protein 3B.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CAPSD_AMVLE
Sequence: MSSSQKKAGGKAGKPTKRSQNYAALRKAQLPKPPALKVPVVKPTNTILPQTGCVWQSLGTPLSLSSFNGLGARFLYSFLKDFVGPRILEEDLIYRMVFSITPSHAGTFCLTDDVTTEDGRAVAHGNPMQEFPHGAFHANEKFGFELVFTAPTHAGMQNQNFKHSYAVALCLDFDAQPEGSKNPSFRFNEVWVERKAFPRAGPLRSLITVGLFDEADDLDRH
What is the function of this protein?
Capsid protein.  Binds to the to the 3' end of the nonpolyadenylated viral RNA and is involved in viral RNA translation initiation.  Probably binds RNA and plays a role in packaging.
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the alphamovirus/ilarvirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: MU165_SCHPO
Sequence: MLEKGEHIEYPNTPPLHSPPESHTFSSQTDDSYFHKPSSTGLFATLVADTNSSVPSASRSPESIASSQSNDSAAIPSYRRKRRKVRKPEIVKPTLRKRGRKPKNISTLEHDKSKPVISSLIDEDANLSQIKARKSVLESRFSRLEEAFRDFYIKNLEKTEDLIRTDSHFVLNKELLSFRNDYEHRRKHYEKYSQCLNKQLDHFFSYKVTTVHKSYQRFATLLRRHLLDKTAKRYHDLCEKRPYKYITTDLLSPSLTCFASDILQTVPEYTSSQSSPVLLPATPSIVTNKQMMDDLTLCNV
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 165 protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: YE19_YEAST
Sequence: MKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVISVMVGKNVQKFLTFVEDEPDFQGGPIPSNKPRDGLHVVSSAYFEIQ
What are the official names of this protein?
Uncharacterized protein YER189W.
Protein: SYG_BACCZ
Sequence: MYSMEQVVNLAKHRGFVFPGSEIYGGLANTWDYGPLGIELKNNVKKAWWKKFIQESPYNVGLDAAILMNPKTWIASGHVGNFNDPMIDCKKCKARHRADKLIEDALDAKGIEMVVDGLTFDQMADLMKEHEVKCPDCGSEEFTEIRQFNLMFKTFQGVTESSTNEIFLRPETAQGIFVNFKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFTFRTREFEQMELEFFCKPGEDLEWFAFWRETCKNWLLSLGMTEESMRLRDHGEEELSHYSNATTDIEFKFPFGWGELWGVASRTDFDLKRHMEHSNEDFNYIDPQTNERYVPYCIEPSLGADRVTLAFLCDAYEEEQLENDSRTVLRFHPALAPYKAAILPLSKKLSEGATEVFAELAKDFMVDFDETGSIGKRYRRQDEIGTPFCITYDFDSVEDKAVTVRDRDTMEQVRMPISELKGFLEKKIQF
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBA_DRYME
Sequence: VLTEEDKSRVRAAWGPVSKNAELYGAETLTRLFTAYPATKTYFHHFDLSPGSSNLKTHGKKVIDAITEAVNNLDDVAGALSKLSDLHAQKLRVDPVNFKLLGHCLEVTIAAHNGGPLKPEVILSLDKFLCLVAKTLVSRYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit alpha-A, Alpha-A-globin, Hemoglobin alpha-A chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.