PharMolix/UniProtQA huggingface dataset:
Protein: AROE_SULIN
Sequence: MLEEINYDTKLFGLIGKNIKYTLSPYIHNFSFTTLGINAVYLVFDLDEMKFNRIINGLLEIAEGLNVTIPYKEEVMKYLDNTDTYSTRIQAVNTIYKKGGYNTDYLAIKNLVRKKIGNMSGYECYVYGAGGAAKAAAFALSELGCSSISIVNRTNLRANELVELLNKNGYNASIKENCNSTSNIVVVNSTPNPSVVPENCIQKSELVIEFVYKPVETELIKNAKKYSIKYIDGLEILVNQAVEAEKIWFNKSVSDEKIIEYLYARKLVW
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: RS4_ACIBY
Sequence: MARYIGPKCKLSRREGTDLQLKSGVKPFDVKTKKANKAPGQHGQARGGKQSEYSLQLREKQKVRRIYGVLERQFSNYYKEAARVKGATGENLLKLLESRLDNVVYRMGFGSTRAEARQLVSHRSITLNGRRVNIASIQVKAGDVIAVHEGAKQQLRIKNAIELAAQRGIPAWIEVDHSKLEGTFKAAPDRSDLPAEINESLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: WZYE_SALAR
Sequence: MNLMQFSGLLVVWLLSTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAACFYGVYYVTYKTRLRKRVVDVTRKPLFTMNRVETHLTWVILMGIALVSVGIFFMHNGFLLFRLHSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGLNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYHNIDFQGLAPIVRDFYVFIPTWLWPGRPSIVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFLVVFGASLLVAKLLFWLFDSAGLIHKRTTSLPQAQVERKL
What is the function of this protein?
Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units.
What are the official names of this protein?
Probable ECA polymerase.
What is the protein family that this protein belongs to?
Belongs to the WzyE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ADDB_CLOTE
Sequence: MSLKFIYGRSGSGKSYYCFQDIKRKIEENSDKKLILLVPEQFSFQSEKNLINYIGERAVSRAEVLSFKRMAYRVFNEVGGVTHRYMNESGKNMLLYSILNELTGELKIFNNAANKNGFVSTLSDIITEFKRYNLTPEMIKEYLEVAEEREDNILKGKLQDIYLIYSKFQDSIRKKFIDEEENLTILADKLKESKYFDGAYIWVDEFFNFTPQEYLVLEELLLKAEKVNITLCTGGLNEGERIDNLDLFLPVKNTEEKILEFVKRNNIKYEKPIKLNCDPCYRFKNSKELSHMEKNLFAFPYKIHEKYTEDICVFQALNEYSEIEYTARDIIKLVRDNGFRYKDIAVITGDLEGYQSLIKAVFTEYGIPYFIDKKVEGDNNPLVIFILSSLEVLNKNWNYESVFRYLKAGLVDIKREEIDIIENYVLANGIRGKRWIEEKDWDYKILYGFNLTEEKEEEEEEKLKKINEIRRKITEPLIEFHNNIKGEITPKKMCLELYNFLEKMNISSKIESWIKYFKERNRLDKINEYKQIWDVAIGLMEQLVEVMKEEKLNSRTLENIFKSGFEQYELGIIPPSLDQVLVSSTKRLRSHEIKALYIVGTNDGVFPSVLDENGILSDLERENLRETGLEVAKDTKSTAFEEQFLMYVTLTTMSDYLRISYPIANEEGKTLRPSIVISRLRKIFPNLCEKSNVIKEEGDIEKISSPKPTFNEFISQLRVKEEGLELSSIWLSVYDWFMNNKEWKEKFINISQGFNHTNYAEIVDTRRVRKLYGSKLNMSVSRLEKFSQCPFAYFIRYGMNAKERKIYKVSTPDIGTLMHDVVESFSRHIEGKNISWEEIDRELCESFVSTMVDEKIKDMKGSILNSSPRYKHMTNRIKDILSKSMEVISQQISRGDFKPSAYELAFGFNGDFPPISIELSSGEKVNLIGRIDRVDKLENEDGTFIRIIDYKSGKQDFNLSDIYYGLQIQLLVYLDALLQEIEDSAKKEVNPAGILYFNMDDPLISTKKEITKEEAEKEILKKLKLKGLVLKDANIIKAMDNLISGYSDIISVRVNKDGSPSKNSSVADLEDFQLLRDYVRKLIVELCEEMLEGNISIKPYKKNNYTPCGFCDYSAICQFDTSIKGSQYRFINDKKDDEVLQCIREEMKED
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: TSAD_TREPS
Sequence: MNVLGIETSCDETAVAIVKDGTHVCSNVVATQIPFHAPYRGIVPELASRKHIEWILPTVKEALARAQLTLADIDGIAVTHAPGLTGSLLVGLTFAKTLAWSMHLPFIAVNHLHAHFCAAHVEHDLAYPYVGLLASGGHALVCVVHDFDQVEALGATIDDAPGEAFDKVAAFYGFGYPGGKVIETLAEQGDARAARFPLPHFHGKGHRYDVSYSGLKTAVIHQLDHFWNKEYERTAQNIAAAFQACAINILLRPLARALQDTGLPTAVVCGGVAANSLLRKSVADWKHARCVFPSREYCTDNAVMVAALGYRYLIRGDRSFYGVTERSRIAHFSKRGGDRLAAQRSAASQPLF
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLSA_PHOPR
Sequence: MKPTKELLAGILDEVRPLIGQGKVADYIPALAGISATKLGIAVCYNDGEIIQAGDTQERFSIQSISKVMSLTLAMSLYEPEEIWRRVGKEPSGHAFNSMIQLELENGIPRNPFINAGALVVSDLLHSRLAAPQYRMLELVRKLSCNPHLTYDKAVAASEMQHSDRNASIAYLMRSFGNFENEVMPVLTNYFSYCSLNMSCIDLARTFSYLANKGLPLGAKKTIISQTQSKQMNALLATCGLYDGAGEFAYRVGMPGKSGVGGGIVAIVPGEMSITVWSPELDPSGNSLAGTAALELLAERIGRSIF
What are the official names of this protein?
Glutaminase.
What is the protein family that this protein belongs to?
Belongs to the glutaminase family.
Protein: DNAA_CUPMC
Sequence: MQDFWQAAAAQLERELTPQQFKTWIKPLAPVAFDEEAHALRIAAPNRFKLDWVKSQFSGRITALACEYWETQVSVHFVLDPAASGRAAAYTQQAMQQGQDAPAAMGTAMGAGHAPYPGMAGMAGGQSYGPAGAQVPGAHPNQMAGYPDYPSQSNGAPAGYGGAAGGQTPYSQSQQSAQGRGAAPTGHPLQGNSAAHLPDMGEIDVAQMDPAEASARSYRVPSPQPAAPAGAQQQSDTVHERSRLNPILTFDNFVTGKANQLARAAAIQVANNPGKSYNPLYLYGGVGLGKTHLIHAIGNFMLMENPRARIRYIHAEQYVSDVVKAYQRKAFDEFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEALIANRAQVIITSDTYPKEITGIDDRLISRFDSGLTVAIEPPELEMRVAILMKKAAAENVSVPEEVAFFVAKHLRSNVRELEGALRKILAFSNFHGKDITIDVTREALKDLLTVQNRQISVENIQKTCADFYNIKVADMYSKKRPANIARPRQIAMYLAKELTQKSLPEIGELFGGRDHTTVLHAVRKIAEERSKDAQLNHELHVLEQTLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_GEOMG
Sequence: MSEITDVYAREILDSRGNPTLEVEVFLESGVMGRAAVPSGASTGEREALELRDGDKSRYLGKGVLKAVDNVNNIIAEQIIGMEATDQIGIDQRMLDLDGTEYKSNLGANAILGVSLAVAKAAAEEVGLPLYQYIGGSNAKELPLPMMNILNGGAHADNNVDIQEFMIMPAGAKSFAEALRMGAEIFHALKGVLKGKGYNTAVGDEGGFAPNLKSNEEALEVIMDAIQKAGYKPGEEVLLALDVASSELFNDGVYTLENEAEPKKTPAQMVDFYENLVNKYPIVSIEDGMAENDWDGWKLLTDRLGKRIQIVGDDLFVTNPRILKEGIQKGIANSILIKLNQIGSLTETLDAIEMAKRAGYTCVISHRSGETEDTTLADLSVAVNAGQIKTGSLCRTDRVAKYNQLLRIEDELDTTALFRGKDVFYNIRK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TPS1_XANST
Sequence: MEVKQEVLRPVSNFKPSIWGDQFLVYDEKEEDATVAQLIECLKEEVRKEIMVALDDRNKHANLLKLVSDIQRLGISYCFKQEIEQALGHIYDVYGDEWEGGSLSIWFRLLRQQGFFVSCDIFKKYKNNDGTFKDSLTRNVEGMLELYEAAYLRVRGEVILDDALAFTKGQLEKITKDPLQWNCNLSLSKHIKEALERPIWKRLPRLEVVRYIPFYEQQDSHNESLLRLAKLEFNRLQSLHKRELSQLSKWWKDFEPTKNLHYVRDRLVELYFWVLGVYFEPQYSRSRIFLTKVIKIATVLDDTYDNYGVYDELEIFTDAIDRWSITCIDALPDYMKFIYKILLDTYGEMEEIMASEGKAYQVYYAKEALKELSRNYMIEAKWTNEGYEPTLKEHETVSFITAGYQMLTPSSFVGMGETVTEEPFKWALTFPPLIKSASVVSRIMDDIIGHKEEGKRKHVVSTVECYMKEHDVTEEYVYDLFKERVEDAWKDMNLELLTCENIPLALKMRTINLARVIESIYKYDDNLKNVGAEIQDNIKSCFIISMSI
What is the function of this protein?
Sesquiterpene synthase involved in the biosynthesis of volatile compounds (PubMed:26858282).  Mediates the conversion of (2E,6E)-farnesyl diphosphate (FPP) into germacrene D, (-)-(E)-beta-caryophyllene and beta-copaene (PubMed:26858282).
What are the official names of this protein?
Sesquiterpene synthase TPS1, Beta-caryophyllene synthase, Beta-copaene synthase, Germacrene D synthase, Terpene synthase 1, XsTPS1.
What is the protein family that this protein belongs to?
Belongs to the terpene synthase family. Tpsa subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IOLD_LISIN
Sequence: MTEKTIRLTTAQALVKFLNQQYIEVDGESAPFVDGIFTLFGHGNVVGIGQALEENPGHLKVYQGKNEQGMAHAAIAYAKQKNRKRIYACSTSAGPGSANLITAAGTAFANNLPVLFLPADTFATRQPDPVLQQLEHESSTAITTNDGFQAVSKYFDRVQRPEQLMSALIRAFEVMTNPVSAGPATICIAQDTEGEAFDYPVTFFQKRIHYLNRQIPTKRELTEAAKLIKASQTPVIIVGGGARYSDARKELIALSEQNDIPLVETHAGKSTVEFSFKNNLGGTGILGTLAANKIIHEADLVIGIGTRYTDFTTSSKTAFNPATKFININVSRMQTYKLDAFQVVGDAKATLIELTPLLKGYKTQFGDKISTYKKEWLKERTRLQHTKFNRDNFAPEIKNQFDQTTLNEYADSLQTEFTQTEALITINDTVAPDSIVVCSAGSLPGDLQRLWNPAVPNTYHLEYGYSCMGYEINGALGAKMAASDNQEVYSIVGDGSFCMSHSELLTSLQYGKKINIMLFDNSGFGCINNLQMANGSDSFFCEFRDNNNQIMQVDYAKIAEGYGAKVYKANTKEDLVNALEDAKKQTKTTLIDMKVLPKTMSEGYLNWWNVGVSEVSNKESITRAYEAKQINLKKARLY
What is the function of this protein?
Involved in the cleavage of the C1-C2 bond of 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy-glucuronate (5DG).
What are the official names of this protein?
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase, THcHDO hydrolase.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family.
Protein: VATL_KALDA
Sequence: MSSTFSGDETAPFFGFLGAAAALVFSCMGAAYGTAKSGVGVASMGVMRPELVMKSIVPVVMAGVLGIYGLIIAVIISTGINPKAKSYYLFDGYAHLSSGLACGLAGLSAGMAIGIVGDAGVRANAQQPKLFVGMILILIFAEALALYGLIVGIILSSRAGQSRAD
What is the function of this protein?
Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase.  V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.  Necessary for the crassulacean acid metabolism.
What are the official names of this protein?
V-type proton ATPase 16 kDa proteolipid subunit, V-ATPase 16 kDa proteolipid subunit, V-type H(+)-ATPase 16 kDa subunit, Vacuolar proton pump 16 kDa proteolipid subunit.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase proteolipid subunit family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein. Note=Tonoplast.
Protein: TTLL3_XENTR
Sequence: MAHHTAVNPDRLKHAKALVEKAIKQKKIFAIHGPYPVIRSCLRSRGWVEKKFPKSGKAKQKKEKASDEDMEDDDGDGSSNDDDDGENSDEEENGDPDGTCDLMSRLLRNEDPNFFWTTKRDAVDCRFLKKDQMLNHYAKAGSFTTKVGLCLNLRNLHWFDDADPDSFFPRCYRLGAEDEKQSFKEDFWHTAARSILKRVANRRDICSPAATGGAKASHREPGANNGAQLLAKRGSRKRAESVPVQIILTALEACERYLNSLEHNDIDMETEATPAMTDTQWEEFLHGYYQVIHDGATIEHSEYYVDQCSEVLHKLEAVNPQLDIEGGRNIWIVKPGAKSRGRGIICMDRLEEILKLVDCDPMIVKDGKWVVQKYIERPLLIFGTKFDVRQWFLVTDWNPLTIWFYKECYVRFSSQPFSLENLDTSIHLCNNSIQKHYENSQSRHPLVPTDNMWSSRQLQVHLHKLGAPHAWEAVIVPGMKAAIIHAMQSAQDIVEYRKSSFELYGADFMFGENFHPWLIEINASPTMAASTTVTSRLCAEVQEDTLRIVLDRKLDRNCDIGAFELIYKQCAVDIPQYLGINLLVEGSMVKKPRQLQQPNPNGAFNLSIVQSNKRSVSLLNAKTSGSNPGVGSQDSVKVAVPTRTAPAVMGNDFWTSRTHGTIGRAKTTAAGKENKAAEGGQRNSVMVELVRLPSKRALEQSKEGTNPRQRLFPAPKSCTLEKPIRVRQPIRLKNGGFVDLKFTSLDSGQVQLLRNMKTGMTDPNKMPCLFCKGPSSLTGLHAMCSCSRAGKQAAKPTCLKLSKRIIIGKFHGSSAALSARGTAILTSLLP
What is the function of this protein?
Monoglycylase which modifies alpha- and beta-tubulin, adding a single glycine on the gamma-carboxyl groups of specific glutamate residues to generate monoglycine side chains within the C-terminal tail of tubulin.  Not involved in elongation step of the polyglycylation reaction (PubMed:28576883).  Preferentially glycylates a beta-tail peptide over the alpha-tail, although shifts its preference toward alpha-tail as beta-tail glutamylation increases (PubMed:28576883).  Competes with polyglutamylases for modification site on beta-tubulin substrate, thereby creating an anticorrelation between glycylation and glutamylation reactions (PubMed:28576883).  Together with TTLL8, mediates microtubule glycylation of primary and motile cilia, which is essential for their stability and maintenance (By similarity).
What are the official names of this protein?
Tubulin tyrosine ligase 3, Tubulin--tyrosine ligase protein 3.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme.
Protein: RNY_STRMU
Sequence: MLNILLTLVFSLIGLVIGYAVISARLKKAKETAELTLLNAEQDAVNARSKAEMDAEHIKKTAERESKAYKKELLIEAKEEARKYREEIEKEFKSERQELKQMDARLTERAASLDRKDENLSSKEQLLDSKEQSLSDKSRHIDERELQVKQLEVKKAEELEKIASLSQEQARGIILSETEKNLAHDIANRIKEAEREIKDRTDKTAKDLLAQAMQRLAGDYVAEQTITTVHLPDDSMKGRIIGREGRNIRTLESLTGIDIIIDDTPEVVVLSGFDPIRREIARMTLEALIQDGRIHPARIEELVEKNRLEMDNRIREYGEAAAFEIGAPNLHPDLIKLMGRLQFRTSYGQNVLRHSVEVGKLAGLLASELGENVDLARRAGFLHDIGKAIDREVEGSHVEIGTEFARKYKENPVVINTIASHHGDVEAQSVIAVLVAAADALSSARPGARNESMENYIKRLRDLEEIATSFDGVQNSYALQAGREIRIMVQPEKLSDDDVTILAHKVREKIENNLDYPGNIKVTVIRELRAIDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: NOGG_CHICK
Sequence: MDHSQCLVTIYAAAVLLGLRLQQGSCQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLMGGHFDPNFMAMSLPEDRLGVDDLAELDLLLRQRPSGAMPGEIKGLEFYDGLQPGKKHRLSKKLRRKLQMWLWSQTFCPVLYTWNDLGSRFWPRYVKVGSCYSKRSCSVPEGMVCKPAKSVHLTILRWRCQRRGGQRCTWIPIQYPIIAECKCSC
What is the function of this protein?
Inhibitor of bone morphogenetic proteins (BMP) signaling.  Controls somitogenesis by sequestering the BMP-4 activity which in turn differentiates distinct subtypes of the mesoderm along the mediolateral axis.
What are the official names of this protein?
Noggin, cNoggin.
What is the protein family that this protein belongs to?
Belongs to the noggin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNZ_UNCHF
Sequence: MSLSNSSKVSVLISLLEKSRDLDYIGEAINQLEHSLQCAYFAQRSGADNEMVLAALLHDLGHYCNDTSFEDMGGYGVWQHEKVGADYLRGLGFSERVACLIEGHVAAKRYLVSSKASYLKNLSDASRKTLEYQGGPMDEGERRLFEEREDFKDCLKIRAWDEKGKQTDLKVPGPEHYRKMMEEHLSENQN
What is the function of this protein?
Involved in the degradation of the organophosphonate 2-aminoethylphosphonic acid (2-AEP) (Probable).  Catalyzes the cleavage of the carbon-phosphorus bond of (2-amino-1-hydroxyethyl)phosphonic acid to yield glycine and phosphate through an oxidative mechanism (PubMed:22564006, PubMed:24198335, PubMed:24706911).  It reacts stereospecifically with the R-enantiomer of (2-amino-1-hydroxyethyl)phosphonic acid and is also able to use (R,R)-2-amino-1-hydroxypropylphosphonate as substrate (PubMed:24706911).
What are the official names of this protein?
2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming), Di-iron oxygenase, Nonheme iron-dependent oxygenase.
Protein: CEDA_ECOK1
Sequence: MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVWMLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQENEVEE
What is the function of this protein?
Activates the cell division inhibited by chromosomal DNA over-replication.
What are the official names of this protein?
Cell division activator CedA.
What is the protein family that this protein belongs to?
Belongs to the CedA family.
Protein: RL29_SINMW
Sequence: MKAADVRALSADQLKEELAKLKKEQFNLRFQKATGQLEKSSRIDEVRKDIARIKTIARQKAAEAKA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: PROB_SHIB3
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYSK_STAES
Sequence: MAQKPVDYVTQIIGNTPVVKLRNVVDDDAADIYVKLEYQNPGGSVKDRIALAMIEKAEREGKIKPGDTIVEPTSGNTGIGLAFVCAAKGYKAVFTMPETMSQERRNLLKAYGAELVLTPGSEAMKGAIKKAKELKEEHGYFEPQQFENPANPEIHELTTGPELVEQFEGRQIDAFLAGVGTGGTLSGVGKVLKKEYPNVEIVAIEPEASPVLSGGEPGPHKLQGLGAGFVPDTLNTEVYDSIIKVGNDTAMDMARRVAREEGILAGISSGAAIYAAIQKAKELGKGKTVVTVLPSNGERYLSTPLYSFDN
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: ACRR_ECOLI
Sequence: MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE
What is the function of this protein?
Potential regulator protein for the acrAB genes.
What are the official names of this protein?
HTH-type transcriptional regulator AcrR, Potential acrAB operon repressor.
Protein: ACUK_SORMK
Sequence: MPDDVGPAEAEVSGAVSESDNEYDETEATTKDDDEKMAERSAASEGVETNGDQKKKYDPKDPLRPRRKKARRACYACQRAHLTCGDERPCQRCIKRGLAEACQDGVRKKAKYLHDAPPEALRPVLGPNYNPAAAVSVRNGHRHPSNAGSDAGSSVGTFFSQSTQYPVFSSAATQLGSIPENLPFPQQSPVSPTFQASGNPQLGSIGVNSVSSPMNSFPPALFDPSNPAIFNFNLEGLNFGSQYGAMEFGMLGHMSSGAAETPPRDPSISQQGTAGDVGFNPSGVFGNGLNQFDKVYDNNTGLMSDFLTLDAHSSGLYSQGNLQHGLPHAYAIPAGPTSLQSPSTENNSPQPTGFGFESPTTTNYTGVPGAGGNQPGSQQSRTQKPKTPALGKLGPQSVLGKRQRDPSSIYEAVKEPFQYVASFHKLISLLQNRFSGASTISIVRSLASIRPSFMSCMKTLNRADLIFMEKSFQRALFEHEEFMHQSPSPAIACRRTGEIAGVNKEFTALTGWTKDVLLGKTLNLNANMGGTNSDTLSVSSKGGRGGIVGTTPRLKPLNPEQGPNADGQQQQSQQQKEQPQPVFLAELMDEASVTQFYEDYAQLAFTHSRGTVVRKCRLLKYRTQENMDAAAAAASSVPTTAGGSGSSNGTVVNGGPDSSPAGKTERERSTGANVASNSILSNRVAKIDGEHGISKLERDGKLECSYTWTIKRDVFDIPMIIMINFLPCYYRSHNQLAV
What is the function of this protein?
Transcription factor which regulates nonfermentable carbon utilization.  Activator of gluconeogenetic genes (By similarity).
What are the official names of this protein?
Transcription activator of gluconeogenesis SMAC_06113.
What is the protein family that this protein belongs to?
Belongs to the ERT1/acuK family.
What are the subcellular locations of this protein?
Nucleus.
Protein: BMP6_RAT
Sequence: MPGLGRRAQWLCWWWGLLCSCGPPPLRPPLPVAAAAAGGQLLGAGGSPVRAEQPPPQSSSSGFLYRRLKTHEKREMQKEILSVLGLPHRPRPLHGLQQPQSPVLPQQQQSQQTAREEPPPGRLKSAPLFMLDLYNSLSKDDEEDGVSEGEGLEPESHGRASSSQLKQPSPGAAHSLNRKSLLAPGPGGSASPLTSAQDSAFLNDADMVMSFVNLVEYDKEFSPRQRHHKEFKFNLSQIPEGEAVTAAEFRVYKDCVVGSFKNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWASEEGWLEFDITATSNLWVVTPQHNMGLQLSVVTRDGLHINPRAAGLVGRDGPYDKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQDVSRGSSASDYNSSELKTACKKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGCH
What is the function of this protein?
Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation (By similarity).  Also plays an important role in the regulation of iron metabolism by acting as a ligand for hemojuvelin/HJV (By similarity).  Initiates the canonical BMP signaling cascade by associating with type I receptor ACVR1 and type II receptor ACVR2B.  In turn, ACVR1 propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target.  Can also signal through non-canonical pathway such as TAZ-Hippo signaling cascade to modulate VEGF signaling by regulating VEGFR2 expression (By similarity).
What are the official names of this protein?
Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VGR-1.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: RUTB_AGRRK
Sequence: MSAVTAAGYQAPQERSQSVTLPARPEPITLKPSETAVVVVDMQNAYSTEGGYVDLAGFDIAGAKGTIANIKKTLDAARAAGVQVIYFQNGWDKDYVEAGGPGSPNYHKSNALKTMRQRPELQGQLLAKGTWDYAIVDELQPQPGDILVPKTRYSGFFNTNMDSVLRARGIRNLVFVGIATNVCVESSLRDAFHLEYFGVMLEDATHHLGPDFIQQATVYNVEKFFGWVATVNDFCATVSQAAPTEA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: PABP_ASPNC
Sequence: MSADVSTTPAAENVNGAAEASPAPAAAAPSATTPEVTAVENSTPAPAANQPHSASLYVGELDPSVTEAMLYELFSSIGQVASIRVCRDAVTRRSLGYAYVNYNNTADGERALEDLNYTLIKGKPCRIMWSQRDPALRKTGQGNVFIKNLDSAIDNKALHDTFAAFGNILSCKVAQDEFGNSKGYGFVHYETAEAANNAIKHVNGMLLNDKKVFVGHHISKKDRQSKFEEMKANFTNVYIKNLDSEIDDDEFRKMFEKFGEITSATLSRDQEGKSRGFGFVNFSTHESAQAAVEEMNDKEIRSQKLYVGRAQKKHEREEELRKQYEAARLEKASKYQGVNLYVKNLTDDIDDEKLRELFGPYGTITSAKVMRDTNVERDQSPDSAGKEKEADKENDKEATPEAEKAEKAEEKPSESSEEKDKEAKKSDKKPFGKSKGFGFVCFSSPDEASKAVTEMNQRMVNGKPLYVALAQRKDVRRSQLEASIQARNTIRQQQAAAAAGMPQPYMQPAVFYGPGQQGFIPGGQRGMAFPPQPGMVMGIPGGRPGQYPGPFPGQQGGRGMGPNQQIPPNFAQGIPMGMQGPGGIPNGMGYPQMAQVQFGRGAGGRGQVPGMPMGQGMRGGPGYGQGRGAPVQQGQMRPGQGGRGQNAAAPAGPQEGAAGGVNAQTLGAAPPAQQKQMLGEALYPKIQAQQPELAGKITGMLLEMDNTELLSLTRKPCAPRSMRPLAFTMST
What is the function of this protein?
Binds the poly(A) tail of mRNA.  Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation.  In the nucleus, involved in both mRNA cleavage and polyadenylation.  Is also required for efficient mRNA export to the cytoplasm.  Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation.  In the cytoplasm, stimulates translation initiation and regulates mRNA decay through translation termination-coupled poly(A) shortening, probably mediated by PAN (By similarity).
What are the official names of this protein?
Polyadenylate-binding protein, cytoplasmic and nuclear, PABP, Poly(A)-binding protein, Polyadenylate tail-binding protein.
What is the protein family that this protein belongs to?
Belongs to the polyadenylate-binding protein type-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.