PharMolix/UniProtQA huggingface dataset:
Protein: DMC1B_ORYSI
Sequence: MAPSKQYDEGGQLQLMDAERIEEEEECFESIDKLISQGINSGDVKKLQDAGIYTCNGLMMHTKKSLTGIKGLSEAKVDKICEAAEKLLSQGFMTGSDLLIKRKSVVRITTGSQALDELLGGGIETLCITEAFGEFRSGKTQLAHTLCVSTQLPIHMHGGNGKVAYIDTEGTFRPERIVPIAERFGMDANAVLDNIIYARAYTYEHQYNLLLGLAAKMAEEPFRLLIVDSVIALFRVDFSGRGELAERQQKLAQMLSRLTKIAEEFNVAVYITNQVIADPGGGMFITDPKKPAGGHVLAHAATIRLMLRKGKGEQRVCKIFDAPNLPEGEAVFQVTSGGIMDAKD
What is the function of this protein?
Recombinase that may participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).  Exhibits DNA-dependent ATPase activity when bound to single-stranded DNA (ssDNA).  Mediates renaturation of homologous complementary strands as well as assimilation of single strands into homologous supercoiled duplexes leading to D-loop formation (By similarity).  Binds circular single-stranded DNA (ssDNA) and circular double-stranded DNA (dsDNA) in vitro (By similarity).  Catalyzes DNA homologous renaturation and DNA strand exchange.  The rates of these activities are dependent on the state of ATP hydrolysis (By similarity).  Forms helical filaments along ssDNA and dsDNA, and promotes strand exchange between ssDNA and dsDNA with long DNA substrates of several thousand base pairs.  The presence of the replication protein A is not required for this activity (By similarity).  Seems to be required for homologous pairing and subsequent chromosome segregation during male meiosis (By similarity).  May be not directly required for homologous pairing during male meiosis.  Required for synaptonemal complex assembly and crossover formation.  Functions redundantly with DMC1A (By similarity).
What are the official names of this protein?
Meiotic recombination protein DMC1 homolog B, OsDMC1B, RiLIM15B.
What is the protein family that this protein belongs to?
Belongs to the RecA family. DMC1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KDSA_SHEFN
Sequence: MDQKIIQLSNNVQVANDKPFVLFGGMNVLESRDLAMSIAEHYVEVTQKLGIPYVFKASFDKANRSSVNSYRGPGMEEGLRIFEEIKSTFNVPMITDVHEIHQCAPVAEVVDIIQLPAFLARQTDLVVAMAKTGAVINVKKPQFLAPHEMRHIITKFNEAGNDNIILCERGSSFGYNNLVVDMLGMDEMKQTGYPVIFDATHALQRPGGRADSAGGRRAQATELARSGMALGLAGLFIEAHPDPDNAKCDGPCALPLHLLEKYLTQMKAVDELVKSFEFIDTSK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_ECOHS
Sequence: MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEDA_ECO57
Sequence: MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK
What are the official names of this protein?
Protein DedA, Protein DSG-1.
What is the protein family that this protein belongs to?
Belongs to the DedA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEUC_ALCBS
Sequence: MAGKTLYDKLWDAHLVAEREDGSALIYIDRQIIHEVTSPQAFEGLRLAGRQPWRTSASVATIDHNVPTTPFNSAADITDETSRIQVQTLENNTREFGITEFGIGDVRQGIVHVMAPEQGAVVPGMTVVCGDSHTSTNGALACLAHGIGTSEVEHVLATQTLVAKKMNNMRVSVEGELGPGVTAKDVVLHIIGVIGTAGGTGYALEFAGSAMRSLSMEGRMTVCNMAIEAGARAGMVAVDDVTIDYVKGRPFAPKGADWDKAEAYWRTLVSDADAQFDQQVDIDAADIKPQVSWGTSPEMVVPVDAHLPDPAAETDEVKRSGMTRAYEYMGLTPGMPVTEIKVDRVFIGSCTNSRIEDLRAAAEVAKGRQKAGSVKQVLVVPGSGLVKQQAEKEGLDKIFVEAGFEWREPGCSMCLAMNPDRLEAGEHCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAVAGHFVDIRELDQA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: MIAB_MYCA9
Sequence: MTSTATSGESAVRTYQVRTYGCQMNVHDSERVSGLLDAAGYVKAPEGTDADIVIFNTCAVRENADNKLYGNISHLAPRKAANPNMQIAVGGCLAQKDREGMLAKAPWVDVVFGTHNIGSLPALLERARHNNEAQVEIVEALEHFPSALPATRESAYAAWVSISVGCNNTCTFCIVPSLRGKEIDRRPGDILGEVQALVDQGVLEVTLLGQNVNAYGVNFADPEIPRDRGAFAELLRACGRIDGLERVRFTSPHPAEFTDDVIEAMAQTPNVCPQLHMPLQSGSDRILKAMRRSYRSERFLSIIDKVRSAMPDAAITTDIIVGFPGETEEDFQQTLEVVRRARFSSAFTFQYSIRPGTPAAKLPDQLPKAVVQERYDRLIALQESVTLEENQKQIGRMIEVLIATGEGRKDGETARMSGRARDGRLVHFRPQGHVDGALRPGDIITVDVTGAAPHHLIADDGVRSHRRTRAGDAHEAGKKPSTPGIGLGMPAIGAPKTERIEVAGCGL
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYE2_ALKEH
Sequence: MTPTNVKTRFAPSPTGRMHLGNLRTALFNALLARSRGGRFLLRLEDTDESRSSGAHAQTLMADLRWMGLHWDEGPEAGGEAGPYHQSERGAVYERYYRALEAADQAYPCFCTERELELSRKAQRAAGKPPRYAGTCAHLTAEERERRRAEGRRPTLRFRVPAEETVVFHDLVRGEQRFPTDEIGDFIIRRADGTAAFFFCNAVDDALMGVSHVLRGEDHLTNTPRQLLLLRALDLPQPEYGHINLITGDDGAPLSKRNGSLSVAELREAGWLPEAVLNYLARLGHHYTGEVESQLLDLQGLADAFRTDALGRAPARFDRHQLSHWQQLAVHRADEATLAPWLERLDDAVPADRRRALLAAVRDNILFPDDLAAWGQRVFGPLPALAPDTEAVIRDAGPAFYEAALAELETTAGDFPALAKAVRKATGAKGRQLFMPLRAALTGLCRGPELGPVYALMPVDIARCRLEQARELAATTP
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase 2, Glutamyl-tRNA synthetase 2, GluRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJGA_BACSU
Sequence: MKRNRWIYAVFTILIIGLGLGSRAFSSVLPDTLNTYLGDSLWAAMIFTGCGFLFRKLKTMITGIISLSFCFVIEFSQLYHAEWIDQIRDTSLGGLVLGYGFLWSDIEAYTIGIAACAAIELLVLGIKKRRCM
What are the official names of this protein?
Uncharacterized membrane protein YjgA.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTNB_SCHPO
Sequence: MDDFLKKDLGCLRSGDLKKCGELICEICRDLYTSGWVTGTGGGITIRSGDAIVIAPSGVQKERMELHHLFVMSLITREYMRMPALRLKPSQCTPLFLAVYTLRDAYACIHTHSQEAILLSTLFADSDHFSATGFEVLSYIPKGSKNNGFHKPTDKIKIPFINNTAHESDLHDSLQEAINLYPDTCAVIVRDHGIYCWGDTWQDTKMNTEAVEFLFQAYLRRRRLQKPE
What is the function of this protein?
Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
What are the official names of this protein?
Methylthioribulose-1-phosphate dehydratase, MTRu-1-P dehydratase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. MtnB subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MTH2_HAEAE
Sequence: MKEYKTIDLFAGIGGIRLGFEAFGCKNVFSSEWDKYAQSMYEVNFGEKPFGDINDISPSDIPDHDILLAGFPCQPFSIAGKGLGFADTRGTLFFNIEAILKAKKPKAFLLENVKRLTTHDNGNTFKVINDKLNKLGYTVYHKVLNTLDFGLPQKRERIYIVGFLDKLHFEFPKPIGKYEELSNILESDDVVPNNYFLSDELKRKRLSSITKDVPYPSIWHENISGNVSALPYSCALSVGGSYNYLVVNGVRRLTGPEMLRLQGFPDTFEINIPYSQVRKVAGNSVSVPVIRAIAGSMINSLNMATRKIYQAIQLSLLD
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-RGCGCY-3', methylates C-? on both strands, and protects the DNA from cleavage by the HaeII endonuclease.
What are the official names of this protein?
Type II methyltransferase M.HaeII, M.HaeII, Cytosine-specific methyltransferase HaeII, Modification methylase HaeII.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: AROE_CLOBJ
Sequence: MYTTGLIGKNINYSESPEIHNNYYKKNNIPFFYKIFNLKQDQIDDFIKNLHKNNIKGFNVTIPYKETILQYLNDIVYPADKIGAVNTVAVQEDKLIGYNTDYIGFIKSLQYYNIQVKNFKCLIIGSGGSAKCIYYALKELNARDICIVSRNPEKARLKFEKKVKILNIKDENKLDRYDLIVNCTPIGGPNLKEQKPIELKEIKKNCVVYDLNYTPKRSKLLKEAKENGAFIINGEKMLIFQAYSAIGLWCLNGIKGGR
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: LSRK_PHOLL
Sequence: MNQRRSANPSGKYLMALDAGTGSVRAVIFDLEGNQIAAGQAEWIHQPVPDVPGSMEFDLATNWQLVCQCIRQALKTAQLPASAIQGVASCSMREGIVLYNRNGEPIWACANVDARSSQEVSELKALYDSTFEYDVYRCSGQTLALGAMPRLLWLAHHRPDIYHQATALTMISDWLANMLSGELAVDPSNAGTTGMLDLVSRDWRPDLLEMAGLRSDILSPVKETGTLLGYVTEKAAVQCGLNIGTPVIMGGGDVQLGCLGLGVVKPAQTAVIGGTFWQQVVNLPEPVTDPNMNTRINPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAERLGVDTYSLLEDMAARVPAGAYGVIPIFSDVMRFKAWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLDLISAFSAVKPDSLVFAGGGSKGKLWSQILSDVTGLPVRVPMVKESTALGCAIAAGVGVGLYDAMGATGEKLVRWQHEYQPNPEHCEVYQKAKQDWQAIYADQLTLVDHGLTTSLWKAPGL
What is the function of this protein?
Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon.  Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
What are the official names of this protein?
Autoinducer-2 kinase, AI-2 kinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_CAMC1
Sequence: MEITAQMVKELRESTGAGMMDCKKALGEANGDMEKAVDILREKGLGQAAKKADRLASEGLVSVEVCSKCKKATISEINSETDFVARNPQFQALAKDTTAHIQSSGIKTVEELNTSTLNGVKFEEYFKTQIATIGENLVVRRFETISADDKGVVNGYVHSNGRVGVLIGAACESAEVANKAAEFIRNLCMHAAAMKPSVISYKDLDKDFVEKEFIALRAELEKENEELKRLGKPLHHIPEYASRCQIGEAELAKATKAIEEELKAEGKPEKIWDKIIPGKIERFYADNTVLDQRLTLLGQFYVMDDKKTIEQVIEEKSKELGGKIEIVKYVRFELGEGLEKKVDDFAAEVAAQIG
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_EULFL
Sequence: MNNIRKNHPLMKIMNNSFIDLPAPSNISSWWNFGSLLGACLALQIITGLFLAMHYTADTTTAFSSVAHICRDVNYGWIIRYLHANGASMFFLCLFIHIGRGLYYGSFTLTETWNMGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVLVHLLFLHETGSNNPLGTSSDSDKIPFHPYYTIKDLLGLLLLVLLAMMLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALISSILILAIIPTLHMAKQRSMLFRPLSQCLFWTLTADLFVLTWIGGQPVEYPFITIGQVASILYFTLILILMPMVSLIENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y6527_BACAN
Sequence: MQPYTTVKDEAHVKALTHVPRNKDENGSAFHGVTFLKQLTMDNPNHKNVEIWLNNSFIESNNPNKIDLQSNGWYRYTGEQDLSKVVSILLYINDSLSSSDVAKMNLVYGTHKNGFGDQYVSKTVVNTSVDYKLSPISNQVRYTIVANANIGLRKIRIDTAPAESGLPVTVRLDKDIVYEDSSKDEITVNLYDKADNRLVGSKVYTIGELPEEIKFKVDRKFLKKKSKRNYEVRFEKINKESIFVAEGKNKVDTDGYTSSEETVKANSKESTELKYKGVIMTEREVGKEMEVFHETLTIPLKQLPKQKTGYGFELKTEASYNNELAVPYDIKVGALIDKKLIDSHLNYEQKEGNTYVPLEETNKNISSDKRNNDFTFELPHVNVEQKTGALFTDQQVKDKDSRIKNALKDGKRKLYAPIWADLGDYNIFVKSELPIGANKVNFEVTQPLHVYAFMYGTIGSDTLKDDEILVEPVDPRNPFSNGKPSGWSDEDVAWLKR
What are the official names of this protein?
Uncharacterized protein pXO2-28/BXB0027/GBAA_pXO2_0027.
Protein: Y3228_ARATH
Sequence: MHYSQTSSFGGNHTEIAKIIHKFLQPRVKQYPLWNPPSREYMSRAMACQICEVTINEMDTLLICDACEKAYHLKCLQGNNMKGVPKSEWHCSRCVQAFNGKPFPPTYGRATRAVATTTAKMPFRAAGVLSSSAKKIGPMDIKANQQKPIVSTFSRLQNTGLVSGAATTSQFESASVNAKTTASAAKTTNIGSQGSKENVACGANSPAPVSLTETPNRTGIASTISVINNGLISKPLTPVGTMSSTSPLPVVNQLPVNATSNASPSTPITASLVAQAPTVTQNGDGSSTASGTADHSILNADITTQVHTLTVTSSSNSQQAVSHSEVAKATEDAAPLENVSECEKPSESTSHPDSLNDKTISENVQESSKDAKVDSEACQNHPTASPATVVPDQDSTITAAPSVTQEDSAFNTEKTPPQPLSVSSNYDSQTEKETPNVQDSVHNVPGDSEKGKGLNGLDDRHQEQPSEPEFYKSDSVKEENAA
What are the official names of this protein?
PHD finger protein At3g20280.
Protein: UL95_SHV21
Sequence: MFNLVELAVKGNPELKKRYSQGLDLAIAMSENIPDQFKLIETPTNSFLLISNVMPEDSRPWHTQIQKCLDFSNLHLPKLNKLNKICTGYDHREDTVKKLEAVPPYLVYDSEEWKLALQINKDSLIYSAIEMLADPKNWQGLYPIDPLPYIWLLFYGKKSFCASSDCIYFKKYNVPGPMLLPPHMYRPDKNISSFISHVCQYVKNLYEEVSEPINLEIVPFDNCRIKEAVEELKQIDLPVAYLSNLCLLCTLHRQNMSASRGSGDMCGYIVLGGEGEKYITTNIISKRCTVSGDCLIVPSYNISLLMQNMEINYEQQ
What are the official names of this protein?
Gene 34 protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL95 family.
Protein: RL11_SALTO
Sequence: MPPKKKLVKTFTLQLPAGQATPAPPVGPALGQHGVNIMEFCKSYNAQTESQRGDIVPAEISVYEDRTFTFVLKTPPAARLLIKAAGVAKGSGVPHMEKVGQVSRAQLREIAEKKMADLNANDLDQAEKIIAGTARSMGLNVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL32_XYLFT
Sequence: MAVQKSRVTPSRRGQRRSHDALAAKKLSIDPTSGEVHIRHHVTADGYYRGKKVIAIKASVVEED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ZN813_PONAB
Sequence: MALSQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLDISSKCMMKEFLSTAQGNREVFHTGTLERHESHHIGDFCFQETDKDIHNLEFQWQEDERNGHEVLMTEIKKLTGSTDQYNQSHARNKPIKDQLGSSFYSHLPELHIFQTQGKIDNQVEKSINNASSISTAQRISCRPKTHISNNYGNNFLNSLLLTQKQEVRMREKSFQYNESGKAFNYSSLLRKHQIIHLGEKQYKCDVCGKVFNRKRNLACHRRCHTGEKPYRCNECGKTFSQTYSLTCHRRLHTGEKPYKCEECDKAFSFKSNLKRHRRIHAGEKPYKCNECGKTFSQTSSLTCHRRLHTGEKPYKCNECGKTFSWKSSLTCHHRLHTGEKPYKCNECGKTFSQELTLKCHRRLHTGEKPYKCNECGKVFNKKANLARHHRLHSGEKPYKCTECVKTFSRNSALVIHKAIHIGEKRYKCNECGKTFSRISALVIHTAVHTGEKPYKCNECGKGFYRKAHLVCHHRLHTGEKPYKCNECGKVFNRKTHLAHHHRLHTGDKPYKCNECGKVFNQKAHLARHHRLHTGEKPYKCTECGKVFNQKANLARHHRLHTGEKPYKFSECGTVLN
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 813.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SURE_ACIB3
Sequence: MNILIANDDGVFAPGIQALADALKPLGRVVVVAPESERSGFSSALTLDRPLRPIQIAEDVWAVNGTPADCVYLSMNGLFDFEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAIAVSLAGPDVRSYDHKDDYAQAAKWVHDFIAKGLPALPPRHIFNINIPDVPQLKGTQITYQGRRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPQRIASQIQSDFFAVANGFVSVTPIQMDATNYAVLEDLQASLG
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_NITMU
Sequence: MSFKVSRQTYAELMGPTTGDRIRLADTELMIEIEKDFTTYGEEVKFGGGKVIRDGMGQSQHNHDQVMDTVITNAVIIDHWGIVKADVGLKNGRIAEIGKAGNPDIQPNVTMSIGAATEIIAGENMILTAGGIDSHIHFISPQQAEDAMMNGITTMLGGGTGPAAGTAATTCTPGPWHIHSMLRASDGMVMNTGFYGKGNVSLPTPLEEQILAGACGLKLHEDWGSTYAAIDNCLAVADKYDVQVAVHTDTINEGGYLENTIAAMKDRTIHTFHTEGAGGGHAPDIIAVVGQENVLPSSTNPTRPYTINTLDEHLDMLMVCHHLHANIPEDLAFAESRIRKETIAAEDILQDMGAISMMSSDSQAMGRIGEVVLRTWQTAHKMKIQRGTLQEDTSKNDNFRVKRYIAKYTINPAITHGISHALGSVEVGKYADLVLWRPAFFGVKPSVILKGGMIAASLMGDPNASIPTPQPVHYRYMFGGYGGGIKTSCFTFVSQAALAAGLVDQLKLDKNLIEVKNTRNLRKKDMIHNSATPKMEVDPETYEVRADGQLLTCGAEDVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SENP1_MOUSE
Sequence: MDDTADGVKMDAGEVTLVNHGSTFRTHRPPQSGFPEEQLLLSDQQSLPFRQGTLDGSFTCSTRSPAYRPDYHSDNPSSDSFLGSGDVRTFGQSANGQWRNSTPASGSAPQKPRNSRSLCLETRKTSSGLSNTFVGKSNHHCHMSAYEKSFPIKPAPSPSWSGSCRRSLLSPKKTQRRHFSTAEETVQEEEKEIYRQLLQMVTGKQFCVAKPTTHFPLRLSRCLSSNKNSLKDSLLRNGNSCASHVIGSDTSSSGSASILTAQEQLSHSAHSLSSGTPDVAFGSKDSDPHHHLAAPHQPNSLPASNTQSEGSDSVILLKVKESQTPASSPTFFQAELWIKELTSVYDSRARERLRRIEEQKALALQLQNQRLQEQEHAVLDSVELHLRVPLEKEIPVTAAQETRKKSHQLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGFPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRRKSITYYDSMGGINNEACRILLQYLKQESVDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
What is the function of this protein?
Protease that catalyzes two essential functions in the SUMO pathway (PubMed:15923632, PubMed:29499132).  The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins.  The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein.  Deconjugates SUMO1 from HIPK2 (By similarity).  Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity (By similarity).  Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity (By similarity).  Deconjugates SUMO2 from MTA1 (By similarity).  Deconjugates SUMO2 from MTA1 (By similarity).  Deconjugates SUMO1 from METTL3 (By similarity).  Desumoylates CCAR2 which decreases its interaction with SIRT1 (By similarity).  Deconjugates SUMO1 from GPS2 (PubMed:29499132).
What are the official names of this protein?
Sentrin-specific protease 1, SUMO-1 protease 2, SuPr-2, Sentrin/SUMO-specific protease SENP1.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Shuttles between cytoplasm and nucleus.
Protein: CBPM_SALAR
Sequence: MANITVTFTITEFCLHTGVTEEELNEIVGLGVIEPYEDDNANWQFDDRAASVVQRALRLREELALDWPGIAVALTLLEENSRLREENRQLLLRLSRFISHP
What is the function of this protein?
Interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA.  Together with CbpA, modulates the activity of the DnaK chaperone system.  Does not inhibit the co-chaperone activity of DnaJ.
What are the official names of this protein?
Chaperone modulatory protein CbpM.
What is the protein family that this protein belongs to?
Belongs to the CbpM family.
Protein: SYS_VEREI
Sequence: MLDILLLRKDPASAIARLETRQKPQPFLNLSAFQALEAERKTLQTRTEELQSRRNQLSRQIGISLGQGDPGSADTARAQVAASKLELAQSAARLEQIQAELQTMLEAVPNLPHDSVPVGADASGNIELRRWGQPASPAFALKDHVDIGRPLGLDLDLGVKLSGARFAVMKGQIARLHRALAQFMLDVQTGEHGYTECYVPYAVNAESLKGTGQLPKFESDLFSTKKGGQDGEPVPDNTALYLIPTSEVPLTNFVRGLVLTEAELPIRLTAHTPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVHPATSYQALEEMTGHAEALLQKLGLPYRVMSLCTGDMGFGAAKTYDLEVWLPAQNSYREISSVSNCEAFQARRLQARFKNAQGKNEPVHTLNGSGLAVGRTLVALLENYQQADGSVTIPPALRPYMAGIAALRP
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COPB_DROPS
Sequence: MSQVPCYTIINSPDLEVPNEMQLKQDLEKGDTNHKIETLKKVIKLLLNGERYPGLIMTIIRFVLPVQDHTIKKLLLIFWEIVPKTSGDGKLLQEMILVCDAYRKDLQHPNEFLRGSTLRFLCKLKEPELLEPLMPAIRACLDHRHSYVRRNAVLAIFTIYKNFDWLVPDGPELIANFLDTQQDMSCKRNAFLMLLHADQERALNYLASCIDQVHSFGDILQLVIVELIYKVCHANPAERSRFIRCIYNLLNSSSNAVRYESAGTLITLSLAPTAIKAAASCYIELIVKESDNNVKLIVLDRLIAMKENENMEKVMQDLVMDVLRVLAAPDIEVRRKALALAMDLVYSRNIGEMVLVLKKEVAKTHNVEHEDTGKYRQLLVRTLHTCSIKFPDVAATVIPVLVEFLSDTNELAAADVLIFIREAIQKFPALSGLIIEHLIEAFPQIKSSKIHRAAVWILGEYVEGPQIIEVIDAIQQTLGDVPMVEAEQRRLSGDPTEEQSQQQGSATGGVSGDGSSSTTTSTSNAINKVTSDGTYATQSAYSLAPVAKVEKRPPLRQYLMDGDFFIGAALSATLTKLALRYVELQPDSSAQNRLTTRVMLIMSSILHLGKSGFPSKPITNDDTDRIFICLRTLSERTPEAVSVFMHYCREALGKMLDAQHDEDQRVLKEKQRATAKVQPDDPVLFAQLSNGRDNQLGENVFESSLNQALAGTKTAQLSDISSPNNKLNKVTQLTGFSDPVYAEAYVNVNQYDIVLDVLIVNQTNDTLQNCTLELATLGDLKLVERPHPVVLAPHDFCNIKANVKVSSTENGIIFGNIVYDTALNTNVVVLNTIHIDIMDYIIPASCTDTEFRQMWQDFEWENKVTVNTSFTDLHEYLRHLLKSTNMKCLTPEKALSGQCGFMAANMYAKSIFGENALANLSIEKPVDDPDSKVTGHIRIRAKSQGMALSLGDKISSSQKQSVQAA
What is the function of this protein?
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.  Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.  Required for limiting lipid storage in lipid droplets (By similarity).
What are the official names of this protein?
Coatomer subunit beta, Beta-coat protein, Beta-COP.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. Present within the clusters of tubulo-vesicular structures of Golgi membrane and cis-Golgi membranes.