PharMolix/UniProtQA huggingface dataset:
Protein: GBG12_PONAB
Sequence: MSSKTASTNNIAQARRTVQQLRLEASIERIKVSKASADLMSYCEEHARSDPLLIGIPTSENPFKDKKTCIIL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ARAP3_HUMAN
Sequence: MAAPQDLDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVPKPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPTPALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPYASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEISVVSAADTPDKKEHLVLVETGRTLYLQGEGRLDFTAWNAAIGGAAGGGGTGLQEQQMSRGDIPIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCLPRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGYISVFDIDSDQVAQIDLEVSLITTWKDVQLSQAGDLIMEVYIEQQLPDNCVTLKVSPTLTAEELTNQVLEMRGTAAGMDLWVTFEIREHGELERPLHPKEKVLEQALQWCQLPEPCSASLLLKKVPLAQAGCLFTGIRRESPRVGLLRCREEPPRLLGSRFQERFFLLRGRCLLLLKEKKSSKPEREWPLEGAKVYLGIRKKLKPPTPWGFTLILEKMHLYLSCTDEDEMWDWTTSILKAQHDDQQPVVLRRHSSSDLARQKFGTMPLLPIRGDDSGATLLSANQTLRRLHNRRTLSMFFPMKSSQGSVEEQEELEEPVYEEPVYEEVGAFPELIQDTSTSFSTTREWTVKPENPLTSQKSLDQPFLSKSSTLGQEERPPEPPPGPPSKSSPQARGSLEEQLLQELSSLILRKGETTAGLGSPSQPSSPQSPSPTGLPTQTPGFPTQPPCTSSPPSSQPLT
What is the function of this protein?
Phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein that modulates actin cytoskeleton remodeling by regulating ARF and RHO family members.  Is activated by phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) binding.  Can be activated by phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4,5)P2) binding, albeit with lower efficiency.  Acts on ARF6, RAC1, RHOA and CDC42.  Plays a role in the internalization of anthrax toxin.
What are the official names of this protein?
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, Centaurin-delta-3, Cnt-d3.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, lamellipodium. Cell projection, ruffle. Note=Cytoplasmic, and associated with F-actin-rich membrane ruffles and lamellipodia.
Protein: CML6_ORYSJ
Sequence: MESHLNEQQISDFRDAFSLFDKNNDGCISREELATVLTRLGMAPSQEDLQDMIVAVDEDGNGTIEFDEFLAIMKKKLYENDKGDDEEELRKAFRIFDKDDNGFISRNELSMVMASLGEEMTEDEIDDMMKAADSNNDGQVDYEEFKRVMMSTWNITEIFKPHVTIWRYKP
What is the function of this protein?
Potential calcium sensor.
What are the official names of this protein?
Putative calmodulin-like protein 6.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: Y144_ADEG1
Sequence: LTPIISVQFKPPPTRDFPVVVEKGFEKRAHYFRGFINSGHAQIQKGQTHHHGHMTFAWRQGLDTDTIRHRILNVHIGPCIYSVPPPLDRSHESPEEFFPPQNRNRGGGPKAQIQRHPPEALEKTTH
What are the official names of this protein?
Uncharacterized 14.4 kDa protein.
Protein: DDX46_PONAB
Sequence: MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAMENIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEEVDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGITVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSATFPRAMEALVRRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKFDETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSAPAPTAGNAEKLEIAKRLALRINAQKNLGIESQVDVMQQATNAILRGGTILAPTVSAKTIAEQLAEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISEYSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSYQPTNKGRYKVL
What is the function of this protein?
Plays an essential role in splicing, either prior to, or during A complex formation.
What are the official names of this protein?
Probable ATP-dependent RNA helicase DDX46, DEAD box protein 46.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily.
What are the subcellular locations of this protein?
Nucleus speckle. Nucleus, Cajal body. Membrane; Lipid- anchor. Note=Present in Cajal bodies (CBs) and nuclear speckles.
Protein: GLYA_ECODH
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERIKGKVLDICARYPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NODJ_BRADU
Sequence: MDDGYASVMPANAYNWTAVWRRNYLAWRKVALASLLGNLADPITNLFGLGFGLGLIVGRVEGTSYIAFLAAGMVAISAMTSATFETLYAAFARMDVKRTWEGILFTQLTLGDIVLGELVWAASKSVLAGTAIGIVAATLGYASWTSVLCAIPTIALTGLVFASLAMVVISLAPTYDYFVFYQSLVLTPMVFLCGAVFPTSQMPDSFQHFAGLLPLAHSVDLIRPVMLERGADNAALHVGALCVYAVLPFFASIALFRRRLLR
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit encodes the transporter (By similarity).
What are the official names of this protein?
Nodulation protein J.
What is the protein family that this protein belongs to?
Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: AROQ_CAUSK
Sequence: MVKPIHVLSGPNLNLLGTREPEIYGKDTLDDVRARCKARAAVRGLSVVFRQSNHEGALIDWVQEARTEACALVINPAGYGHTSIALLDALKTLNIPVIECHLSNPAAREDFRRHTYVSLAATGIVSGFGAASYELAIEAAAGLVGAN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: TUSC_VIBVU
Sequence: MSQLTYLFRTAPHSHSSGREGVDALLAASAYCEAISVVFIGDGVYQLLAGQQTASILCKDYAPMFKLFDLYDIEHVYVCQQSLQQRGLTSEDLLIEVEVVDTAQLQGVLHNSAQLLSF
What is the function of this protein?
Could be part of a sulfur-relay system.
What are the official names of this protein?
Protein TusC homolog.
What is the protein family that this protein belongs to?
Belongs to the DsrF/TusC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRF_ALIFM
Sequence: MKDQKVIVALDYDNQADALTFVDKIDPSSCRLKVGKEMFTLFGPEFVKELHKRGFSVFLDLKFHDIPNTCSKAVRAAAEMGVWMVNVHASGGERMMSASREILEPYGSDRPLLIGVTVLTSMEQQDLAGIGLDIAPQEQVKRLAALTKNSGLDGVVCSAQEASMLKADLGKEFQLVTPGIRPAGADVGDQKRIMTPVDAITAGSDYLVIGRPITQAENPSQVLNEINLSLASVL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: RS4_NITMU
Sequence: MARNLDPKCRQCRREGEKLFLKGEKCFTDKCAIERRNYAPGQHGQKSGRLSDYGVQLREKQKLRRIYGVLERQFRNGYELAERQRGVTGENLLQLLECRLDTVSYRMGFGASRSEARQIVRHNGILVNGRRINIPSYQVKPGDVIEVAEKAKNHLRIKASVEAAEQRHFPEWLEVDTKAMKGTFKNKPERSDLPSSINESLVIELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: CLPP_STRZJ
Sequence: MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQSMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACP_BORBZ
Sequence: MDNDEIFSKVRSIISEQLDKKEDEITTDSRFVEDLNADSLDIYELLYLLEEAFDDKIPENEANEFETVGDVVNFIKKRKG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4JR_SINFN
Sequence: MKTLIVEDNPKKRASLVEYYSSEFPSDDLEVTSALISGLRVARDTKPEFIILDMTLPNYSPDENKGSRIELMPFAGREFVMRVNRMSIKTKVIIVSMFETFGVAPRLITLNSLDAELRDRYPNVFVEAVHYSQAQADWKTAIKNARLSLDR
What are the official names of this protein?
Uncharacterized protein y4jR.
Protein: RPOB_SINAL
Sequence: MINAKKMLGDGKEGTSTIPGFNQIQFEGFYRFIDQGLIEELSKFPKIEDIDHEIEFQLFVETYQLVEPLIKERDAVYESLTYSSELYVSAGLIWKTNRNMQEQRIFIGNIPLMNSLGTSIVNGIYRVVINQILQSPGIYYQSELDHNGISVYTGTIISDWGGRLELEIDKKARIWARVSRKQKISILVLSSAMGSNLREILENVCYPEIFLSFLTDKEKKKIGSKENAILEFYQQFSCVGGDPIFSESLCKELQKKFFHQRCELGRIGRRNINWRLNLNIPQNNIFLLPRDILAAADHLIGMKFGMGTLDDMNHLKNKRIRSVADLLQDQLGLALARLENVVKGTIGGAIRHKLIPPTQNLVTSTPLTTTYESFFGFHPLSQVLDRTNPLTQIVHGRKLSYLGPGGLTGRTANFRIRDIHPSHYGRICPIDTSEGINVGLIGSLSIHARIGDWGSLESPFYELVEKSKKAQIRMLFLSPSQDEYYMIAAGNSLALNRGIQEEQVVPARYRQEFLTIAWEEVHLRSIFPFQYFSIGASLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQVALDSGVPAIAEHEGKILYTDTEKIILSGNENTLSIPLIMYQRSNKNTCMHQKPQVPRGKCIKKGQILADGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISECLVYGDIYTSFHIRKYEIQTHVTTQGPERITKEIPHLEGRLLRNLDKNGIVMLGSWVETGDILVGKLTPQVAKESSYAPEDRLLRAILGIQVSTSKETCLKLPIGGRGRVIDVRWVQKKGGSSYNPEIIRVYISQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGRPVDMVFNPLGVPSRMNVGQIFECSLGLAGSLLDRHYRIAPFDERYEQEASRKLVFSELYEASKQTANPWVFEPEYPGKSRIFDGRTGDPFEQPVIIGKPYILKLIHQVDDKIHGRSSGHYALVTQQPLRGRSKQGGQRVGEMEVWALEGFGVAHILQEMLTYKSDHIRARQEVLGTTIIGGTIPKPEDAPESFRLLVRELRSLALELNHFLVSEKNFQINRKEV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: POTA_OCEIH
Sequence: MKNNQPIIQFKNVSKQFDNDPLVLDHVSFTIEKGKFYTLLGPSGCGKTTILRLIAGFTEASSGDIIFEGKRINHIPANKRPINTVFQDYALFPHLNVYENVAFGLRIKKLKKSMIDEKVKEALSFVNLVGYENREIKDMSGGQRQRVAIARAIVNEPAVILLDEPLSALDLKLRYQMQYELRELQQRLGITFIFVTHDQEEALAMSDEIFVLNKGKIQQSGTPNDIYDEPINRFVADFIGESNITKATMIEDYLVEFAGKQFTCVDMGMNANEPVEVVIRPEDMEITSVEQGMISVTVHTQLFRGVHYEITCLDSEGNEWLVQSTKKAIVGEQIGLRFHPEDIHVMRFNESEADFDRRLDSYSEGETDGE
What is the function of this protein?
Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Spermidine/putrescine import ATP-binding protein PotA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GGAG_FLV
Sequence: MSGASSGTAIGAHLFGVSPEYRVLIGDGGAGPSKSLSEVSFSVWYRSRAARLVILCLVASFLVPCLTFLIAEAVMGQTVTTPLSLTLDHWSEVRARAHNQGVEVRKKKWITLCEAEWVMMNVGWPREGTFSLDNISQVEKKIFAPGPHGHPDQVPYITTWRSLATDPPSWVRPFLPPPKPPTPLPQPLSPQPSAPLTSSLYPVVPKPDPPKPPVLPPDPSSPLIDLLTEEPPPYPGGHGPPPSGPRTPAASPIASRLRERRENPAEESQALPLREGPNNRPQYWPFSASDLYNWKSHNPPFSQDPVALTNLIESILVTHQPTWDDCQQLLQALLTGEERQRVLLEARKQVPGEDGRPTQLPNVIDETFPLTRPNWDFATPAGREHLRLYRQLLLAGLRGAARRPTNLAQVKQVVQGKEETPAAFLERLKEAYRMYTPYDPEDPGQAASVILSFIYQSSPDIRNKLQRLEGLQGFTLSDLLKEAEKIYNKRETPEEREERLWQRQEERDKKRHKEMTKVLATVVAQNRDKDREENKLGDQRKIPLGKDQCAYCKEKGHWVRDCPKRPRKKPANSTLLNLED
What is the function of this protein?
Plays a role in viral particle release.  Presumably acts by facilitating the fission of the virion bud at the cell surface.
What are the official names of this protein?
Glyco-Gag protein, Gross cell surface antigen, glycosylated Pr80 gag, gPr80 Gag, gag-gPr80.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein.
Protein: RNH2_PHOV8
Sequence: MLLPYLNKDLIEAGCDEAGRGCLAGSVYAAAVILPVDFKNELLNDSKQLTEHQRYALREIVEREALAWAVGVVTPEEIDEINILNASFLAMHRAVDQLKIRPQHLLIDGNRFKKYQDLPHTTVVKGDGKYLSIAAASILAKTYRDDYMNELHKEYPFYDWNSNKGYPTKKHRAAIREHGTTPYHRMTFNLLGTDPQLEIPF
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APAH_PSEFS
Sequence: MATYAVGDLQGCLEPLKCLLDRVAFDPAKDRLWLVGDVVNRGPESLETLRYLYSLRDSLVCVLGNHDLHLLAASNTIERLKKGDTLREILEAPDRAELLDWLRRQKIMHYDQGRNMALVHAGIPPQWTLKKALKCAAEVESALADDTLYTAYLDGMYGNDPVKWDNDLTGVARLRVITNYFTRMRFCTAEGKLDLKSKEGADTALPGYKPWFAHKERKTRDTKIVFGHWAALEGKCDEPGVFALDTGCVWGGAMTLMNIDTGERYSCQCESPLPVTLPATAKP
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: SYE_METI4
Sequence: MNKMIPRVRFAPSPTGFLHVGGARTALFNWLYARHFKGTFILRIEDTDQSRNTPQALSVIFDNLSWLGLDWDEGPLPDGSSKGQFGPYFQSQRKEIYNEYCNRLIAKELAYIKDEAVYFRMPRKRIIVSDLICGDIYFDCSLEKDFVIRRKDGSFVFHLVNVVDDLEMQISHVIRGEDHLSNTPKHIALFEALGMSPPLYAHIPLILNPSGTKMSKRDKGSSVQEYIDEGFLPQAFRNYLCLLGWSLKENREIFGIEEAIAKFDLPQIHRSNARFNHQKLLWINGEYMRSLPLDELYPHAFFWLKKAGLIDQNTDCSFLKQAVGIVREKVKTGKELVEWMKPLLSDTLQYDEAVVQQYLDDKGKEILREALPYLEEVSSFQAKELEAIIKNLSLKMGRKTADYIHRLRVALTGRTVGPSLYPMLEVLGKQKVLNRLYKVVGPKE
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_PROM2
Sequence: MMNILLINGPNLNLLGTREPEIYGNKTLIDIEKDLTKVAKEKSINIECFQSNHEGEIVDKIHDSVKSIQGILINAGAFTHTSISIRDALIGSKIPFVELHISNIFSREDFRKESFLTDKAIGIISGFGISSYFLALEGIIGYLNGKN
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: ILVD_AZOVD
Sequence: MPDYRSKTSTFGRNMAGARALWRATGMKDEDFKKPIIAVANSFTQFVPGHVHLKDLGQLVAREIEKAGGVAKEFDTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADALVCISNCDKITPGMLMASLRLNIPVVFVSGGPMEAGKTKLSQHGLDLVDAMVIAADSSASDEKVEAYERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTIVATHADRRELFLQAGRTIVDLCRRYYQEGDESVLPRAIASRAAFENAMTLDIAMGGSTNTILHLLAAAQEAEVDFDLHAIDALSRQVPQLCKVAPNTPKYHIEDVHRAGGIVAILGELARAGLLNTEVATVHSKTLGEAIEKWDVRVNRDQAVHTFFKAGPAGIPSQEAFSQSERWDSLDLDRAEGCIRDLEHAFSTEGGLAVLYGNIALDGCVVKTAGVDESILVFEGTAKIFESQDAAVKGILGDEVKPGDVVVIRYEGPKGGPGMQEMLYPTSYLKSKGLGKQCALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVEDGDKILIDIPNRSINLLVSDEELKARRLHQDHKGWKPAAPRARKVSTALKAYALLATSADKGAVRNKALLDE
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: ARGC_SYNP2
Sequence: MSSSEKVSVGIVGASGYGGMQLVRLLSDHPQVELTYLGGNSSAGKPYAELYPHVGHRIKMIVEPIDLDVIASRCQVVFLGLPNGLACDLAPQLIERGCKVLDLSADYRFKDLDTYQAWYKTERTDQDTNAIAVYGLPELYRDDIRRAQLVGCPGCYVTASLLALAPLFKQGLIQPETAIIDAKSGTSGGGRQGKINLLLAEADASLGAYGVASHRHTPEIEQICSKLASQDIRVQFTPHLIPMPRGILATVYATLRDPGLVRDDLLTIYSAFYRAAPCVEVLPNGVYPQTKWACGTNLCYLGIEVDHRTGRVIVMSAIDNLLKGQSGQAVQCMNIMLGWEETAGLPQLAFYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU6M_TACAC
Sequence: MMYFIYLLSVMLVLSFMAFASNPSPIYGGLSLVLSGGVGCGIIVSLGGSFLGLIVFLVYLGGMLVVFGYTAAMATEEYPETWVDYTVVLNLAIMVGMLGVVWYEFFEEVDLGVGYDLLDLGGMEVLGGDFNGVSLLYACGGWELVFSGWILFLTIFVVLEVTRGEH
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EFP_STRM5
Sequence: MATAGMNDVKNGMKILVNNEPAVISETEFIKPGKGQAFTRVRYRFIKSGRTVEMTMKATDDVEVADVVDTNMDYMYSDGEYWHFMDPETFEQVQADKAGMGGAEKWLKGEESCIVTLFNGSPIFVQPPNFVELKITETDPGVRGDTSGGGGKPATLETGAVVRVPLFVNQDEIIKVDTRSGEYSSRVK
What is the function of this protein?
Involved in peptide bond synthesis.  Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome.  Modification of Lys-34 is required for alleviation.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_ECOK1
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLK
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: CATB_DICDI
Sequence: MNKKLEQLEKFKTNDKNPVYSTTNTGVSLSDDANSLKAGPRGPTLLEDFVLREKITHFDHERIPERIVHARGTGAHGYFLSYKDHSKLTKADFLSKQDKKTPVFIRISTVQGPRGSADTVRDVHGFAVKFYTDEGNYDLVGNNMPVFFIQDASSFPDFVHAVKMEPQNEMPTGGSAHDTFYDFCGLKPESAHSVLWVMSDRGIPISLRHQQGFGVHSYRFINQEGKSTFVKLHWKPLSGTCSLLWDEAQKIAGKDCDYHRRRFWEDIESGDFPQWELGAQLLDEDLQKKFDFDILDPTKLIPEELTPVIPLGRMVIDRNPDNFFAETEQVAFCVSHVVPGIDFSNDPLLQGRIFSYLDTQLSRLGGPNFNEIPINRPVCPFANNQRDGIHRMTINKGGASYFPNSIDKGYPLLKEPSANKGGFRPYPENISGTKSYDRSETFEDHFSQATMFWNSMSQHEKNHIIAAYTFEISKCSRPEVRTRYVNNILVNIDSVLAEKVAKNLGVKIEPTSTKPIKKIMVKPSPALSQPNLLSGDIVSRRISVIIEKGVDYDDVINFKDDMEKRGAMVMLVSSTLAQVECSGGEMLSPKGTIIGNPSIFFDAVYVPKSTEEATKILSDDGNFLHYILEAFKHLKTIAFGGSVSVIKELLRLPQDHGLLLGNGYKDITEQFFYSLAHHRVWERESKVSKIPA
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.  Its accumulation in prespore cells affords the spores protection from oxidation during prolonged dormancy.  Required for normal developmental timing, possibly through a regulatory role in differentiation and morphogenesis.
What are the official names of this protein?
Catalase-B.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Cytoplasm.