PharMolix/UniProtQA huggingface dataset:
Protein: TRUA_BURP6
Sequence: MRIALGIQYDGAAFCGWQSQPHGKTVQDALERSLAEFAQTSLHTTVAGRTDTGVHGLGQVVHFDTDLDRADFSWVRGTNAFLPPTVAVQWAKPMPDTFHARFAAFERTYYYALYVHPVRSPMLAGRAGWVHTPLDVDAMREAAAHLVGEHDFSAFRSSECQAKSPVKHLYQIGIRPDGDFIHFRFRANAFLHHMVRNLMGCLVAVGRGRYPSSWLAEVLESRDRDCAAPTFMPEGLYLAHVGYPAEFAVPPAQLGSVPWSSVWADLDGRT
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: RUXF_DICDI
Sequence: MSKIEALAPKPFLYDLKGKKIAVRLKWGGMEYRGILASVDSYMNLQLAATEEWIDGANKGPLGEVLIRCNNVLFVRGIDDEQQQSQQQQQE
What is the function of this protein?
Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.  Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes.  Is also a component of the minor U12 spliceosome.
What are the official names of this protein?
Small nuclear ribonucleoprotein F, snRNP-F, Sm protein F, Sm-F, SmF.
What is the protein family that this protein belongs to?
Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Protein: AMER2_XENTR
Sequence: MDLHYDCAESPAAEQPSGKINKTAFKLFGKRKSGSGMPTIFGVKNKGDSKGTGKIGMVRSKTLDGLADVVLESNKKEEPCTEAGAGQLNPEKSPKVLTINADVSSNSSVAKSHSFFSLLKKNGKSENVRGEQAEQKAGSRQKRGLKGLFNSMRWSKKDKSYKDDKEGASESQPGLILPSSLTASLECIKEETQKPLCEKGKSTEDIPADVPLAEHSGDVNTSAEENSLKASEESPCSALITEQPQLEDAPLAQLQENLCQLPQPEVETLQNNKDEHVTGCGDVIADQDDDGGSSMGSKLVPGNGKKVMSKKNTNIVAYQGGGEEMASPEQVDETYVQELFSMIPPSEGASEKTEKVNGTTQASREVKCSDSAQDRNAIKPSKLKQVPVYRKERGDQNSKANEKRQCLRNSDEGYWDSPTPGQEEEEPRSVGKQALARDSCSGDALYDLYTDPDESIAKAQVEEPPLSHSHSKPLSPVTTSCPVKTASSNKESKIPISIKHLPVHTTNQGTDSSSGSATGHPHPVKSELPRTKIPVSKVLVRRVSNKAITETAAGKRAIHDPARKHH
What is the function of this protein?
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning.  Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity).
What are the official names of this protein?
APC membrane recruitment protein 2, Amer2, Protein FAM123A.
What is the protein family that this protein belongs to?
Belongs to the Amer family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2.
Protein: LACC_STAA2
Sequence: MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTRVLAQVGEPVLASGFIGGELGQFIAKKLDHADIKHAFYNIKGETRNCIAILHEGQQTEILEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPVILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEWIIVSLGAQGAFAKHNHTFYRVNIPTINVLNPVGSGDSTVAGITSAILNHENDHDLLKKANTLGMLNAQEAQTGYVNLNNYDELFNQIEVLEV
What are the official names of this protein?
Tagatose-6-phosphate kinase, Phosphotagatokinase.
What is the protein family that this protein belongs to?
Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
Protein: LEPA_RICPR
Sequence: MNNQKYIRNFSIIAHIDHGKSTLADRLIEYCGGLNAREMSQQVLDSMDIERERGITIKAQTVRLVYKAKNGNTYYLNLMDTPGHVDFAYEVSRSLAACEGSLLVVDSTQGVEAQTLANVYQAIANDHLIVPVLNKIDLAASEPDYVKTQIEDIIGIDASEAVLISAKNGIGIDSVLEAIINKLPAPKESSTDILKALLVDSWYDPYLGVVILVRIIDGALRKNMRVKMMRTNSVYTVEHVGFFTPKKHISDVLYAGEIGFFTASIKRVSDCKVGDTITDEKKSCEQALPGFKPNIPVVFCGFYPTDSAEFEHLKDSLAKLRLNDASFEYEMESSSALGVGFRCGFLGLLHLEIIQERLSREFDLDLITTAPSVIYKINMLDGQNLEIHNPADLPDLQKIASMEEPWIKATIIVPDEFIGTVLSLCTEKRGIQLDHSYISNRAKIVYKLPLNEIVYDFYDRLKSCSKGYASFEWQMDVYELSDLVNLRILVNGEVVDALSTIVHRSRAEQRGRALCIRLKDLIPRQQIDIAIQASVGSRIIARETIKALRKDVLSKCYGGDISRKRKLLEKQKAGKKKMRQYGNIEIPQSAFIAALQIGGE
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: CU81_CONCL
Sequence: MKLLLTLLLGSALMCITLADECGLGTHRPVKEVIDNVRTMYYCDCRAGDAERSITVSRCDDNNQKQDDVILTYCGLEQTTGCNTNPYTAAKHDSSGDKPQFYCSCLNYKYEQSHSDYRHWTIRCYMGNICD
What is the function of this protein?
Probable neurotoxin with unknown target.  Possibly targets ion channels.
What are the official names of this protein?
Conotoxin Cal8.1, Conotoxin CalMKLL-1.
What are the subcellular locations of this protein?
Secreted.
Protein: ILVC_ACIF5
Sequence: MKVFYDNDADLALIQKKKVAIIGYGSQGHAHALNLKDSGVSVVVGLRKDSSSWEKAGKAGLEVKEVAAAVAAADVVMILTPDEGQGALYRDEIAPNIRQGAALVFAHGFNIHFGQIHPRADLDCFLVAPKGPGHLVRSTYTQGGGVPSLIAVHQDASGNATNIALSYAKANGGTRAGVIETSFREETETDLFGEQAVLCGGATALVQAGFETLVEAGYAPEMAYFECMHELKLIVDLMYEGGISNMRYSISNTAEYGDLTRGPRVVNADTKAEMKKILTEIQNGQFAREFILENQSGKPTMQAMRRIGAEHPIEVVGSKLRSMMTWIGQSRIVDRSRN
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: DNAK3_THEVB
Sequence: MRSRSNGMGKIVGIDLGTTNSVIAVLEGGKPVVIANAEGSRTTPSVVAFGKDGERLVGQLARRQAVLNPQNTFYAVKRFIGREYSELTAESKRVPYTIRRDESGKVRIKCPRLQREFAPEEISAMVLRKLVEDASRYLGEPVTDAVITVPAYFNDSQRQATRDAGRIAGLNVRRIINEPTAAALAYGLDRQQEQTILVFDLGGGTFDVSILEVGDGVFEVKATSGDTQLGGNDFDKLIVDWLAEDFLAKEGIDLRRDRQSLQRLTDAAEKAKIELSGLLETNIDLPFVTATAEGPKHIETTLSRRQFEDLSQGLLQRLRYPVEQALMDAHLTPSQIDAVVLVGGATRMPMVQDLVRQMIGREPKQNVNPDEVVAVGAAIQAGILAGDVKDILLLDVTPLSLGVETIGGVTKVLIPRNTTIPVRRSDIFSTSENNQSQVEIHVVQGERELAAHNKSLGRFKLTGIPPAPRGVPQIQVSFDLDANGLLQVVALDRFSGREQSVVIQGASTLSEEEIQQMLLDAESNAAGDRQRRARIEKRNRSQDLINRAERQLREAAQEFGYQFAAEQRRGIEALVRQLQEAIRNEDDRQIDLTYAALEERLYDFIRQLRLREEEAEDDEEVFKLPNLREAVNKGLDVVRGRERRRDDDEDEWAEPPRTRRSRSYSQRADSAPWDDWDDDW
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein dnaK3, HSP70-3, Heat shock 70 kDa protein 3, Heat shock protein 70-3.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: MATK_HOTPA
Sequence: MEEFKRYLELDRSQQHDFLYPLIFQEYIYALAHDHSLTTSSSLELEKAGYENNSSLLIVKRLIIHLITQMDHFGFFTNYSSQNPFLGHNTTLYSQILLEGFVVVVEIPFSIRIISSLDLEGKEIVKSHNFRSIHSIFPFLEDKFSHLNYVLDLLIPHSIHLEILVQTFRYWVKDASSLHLLRTFLHKYHNWTNLITPKKSRFSFSKQNKRFLFFFSNFHVYEYESILAFLRNQSSHLHSKSYRPFLDRIYFYEKRDHFVKVFTKYFQAILWSFKDPFMHYVRYQGKALLASKGTFLLMNKWNYYLVNFWQCYFYMWSQPGRIHINKLSNHYLELLGYLSSVGLNSSMVRNQMLENSFLIANVSKKFDMIVPIIPLIRSLSKAKFCNLLGHPISKPVWADLSDSDIIDRFGSIYRNISHYYSGSSKKMSLYRIKYIIKLSCARTLARKHKSTVRAFLKRVGSELLEEFFFEDEFIFSLTFPKASSSSGGLYRTRIWYLDIFCIHDLANYE
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: YFAS1_ASPFU
Sequence: MRRTLFVLFVVAFCFIGSVIANLSLPPGFSLRKRLPRSLVDILHLRHEQGLRDDTELRNWLSKQQPAMNKMFSSSSRENGSEKPVVSDVLPKNRAINIFASLTRQFEPIESRLNDSSKNITVLAPRNSAIQSLPRKPWENPEDYEKFGGVSAYEGQEGEDRAKQNLQRFVEAHIIPASPWREGEEMETLGGEKLKWIKKGDKIYIQPGNVEVDNIAETVINGELWILNSVLNYR
What are the official names of this protein?
FAS1 domain-containing protein AFUA_8G05360.
What are the subcellular locations of this protein?
Vacuole.
Protein: IF3_HALH5
Sequence: MSKDMLVNEGIRAREVRLIGANGDQIGVKSKAEALDMARNVNLDLVCVAPNAKPPVCRIMDYGKYRYEQQKKDKEARKKQKTINVKEVRLSPTIEDHDFNTKLRNARKFLSKGDKVKAAIRFRGRAITHSEIGRNVLERLAKECEDIAIVEAKPKMEGRSMFLVLAPKTDK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
Protein: RL10A_SPOFR
Sequence: MSSKVSRDTLYECVNAVLQASKDKKRNFLETVELQIGLKNYDPQKDKRFSGTVKLKYIPRPKMQVCVLGDQQHCDEAKSLTVPCMDAEALKKLNKNKKLVKKLAKKYDAFLASESLIKQIPRLLGPGLNKAGKFPGLLSHQESMTQKIDEVKATIKFQMKKVLCLSVAVGHVDMTPDELAQNVHLSINFLVSLLKKHWQNVRSLHMKSTMGPPPKLY
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: RL15_PSEAE
Sequence: MQLNDLRSAPGARREKHRPGRGIGSGLGKTGGRGHKGLTSRSGGKVAPGFEGGQQPLHRRLPKFGFVSLKAMDRAEVRTSELAKVEGDVVSLQTLKDANLINQHVQRVKVMLSGEVGRAVTLKGIAATKGARAAIEAAGGKFED
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RIBA_HAEIN
Sequence: MAKIQLVAQANLPTEYGIFKMVGFEFPDTKKEHVALVMGDISNADEPVLARIHSECLTGDALHSLKCDCGFQLATALKQIQEEGRGVLIYHREEGRGIGLINKIRAYSLQDKGMDTIEANLALGFKADERNFEVCADMFELLGVKKVRLMTNNPEKVETMKKAGINVVERVPLNVGENRYNTKYLDTKAKKMGHYIVHNNDEQHLMTCPHCQEEII
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: IMAND_ENT38
Sequence: MTPVIIKNIECFITRPDRHNLVTVRVTTEQGITGHGCATFQQRPLAVKTLVDEYLQPLMIGRDANNIEDLWQMMNVNAYWRNGPLMNNAISGVDMALWDIKGQLAGMPLYQLFGGKSRDAIPAYSHASGETLEALFASVDALIAQGYRHIRCQLGFYGGTPSALHAPDNPTPGAWFDQQEYMSNTVEMFHALREKYGWKLHILHDVHERLFPQQAVQLAKQLEPFQPYFIEDILPPQQSAWLEQVRQQSCVPLALGELFNNPAEWHDLIVNRRIDFIRCHVSQIGGITPALKLAHLCQAFGVRLAWHGPGDMTPIGVAVNTHLNIHLHNAAIQEFIPRSATTNDVFPGAPEVKEGFVYPPVQPGIGVGFNEALALAHPVLYRPHEWTQSRLPDGTIHTP
What is the function of this protein?
Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding.  May have evolved a divergent function.
What are the official names of this protein?
D-galactonate dehydratase family member Ent638_0932.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily.
Protein: ALGQ_PSEAE
Sequence: MLESCRNAQERWGGVHQLIDRWLHERQQLVQAFDALSGIQAPAPNAEELQHFCQLLLDYVSAGHFEVYEQLTAEGKAFGDQRGLELAKQIFPRLEAITESALNFNDRCDNGDCREGACLIAELKVLRQQLHERFELEDCLIEVLHNAHSQSGAEGSAVPV
What is the function of this protein?
The promoter for a critical alginate biosynthetic gene, AlgD, encoding GDP-mannose dehydrogenase, is activated only under conditions reminiscent of the cystic fibrosis lung (i. e.  under high osmolarity), and at least two regulatory genes, AlgP and AlgQ, have been implicated in this activation process.
What are the official names of this protein?
Transcriptional regulatory protein AlgQ, Alginate regulatory protein AlgR2.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
Protein: IF12_BURMA
Sequence: MAKDDVIQMQGEVIENLPNATFRVKLENGHVVLGHISGKMRMHYIRIFPGDKVTVELTPYDLSRARIVFRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1 2.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_RUEPO
Sequence: MALERTFSIIKPDATRRNLTGKINAKFEEAGLRIVAQKRIHMTKEQAGVFYGVHAERPFYDELCEFMSSAPVVVQVLEGENAIAKNREVMGATNPADAAPGTIRAEFAESVGENSVHGSDAPETAAVEIAYFFSGIELVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSS8_RAT
Sequence: MALRVGLGLGQLEALFVLLLIGLLQSRIGADGTEASCGAVIQPRITGGGSAKPGQWPWQVSITYNGVHVCGGSLVSNQWVVSAAHCFPREHSKEEYEVKLGAHQLDSFSNDIVVHTVAQIISHSSYREEGSQGDIALIRLSSPVTFSRYIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYNINAVPEEPHTIQQDMLCAGYVKGGKDACQGDSGGPLSCPIDGLWYLAGIVSWGDACGAPNRPGVYTLTSTYASWIHHHVAELQPRVVPQTQESQPDGHLCNHHPVFNLAAAQKLSRPILFLPLSLTLGLFSLWLEH
What is the function of this protein?
Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates.  Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G) (By similarity).
What are the official names of this protein?
Prostasin, Channel-activating protease 1, CAP1, Serine protease 8.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. SUBCELLULAR LOCATION: [Prostasin]: Secreted, extracellular space. SUBCELLULAR LOCATION: [Prostasin light chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus. SUBCELLULAR LOCATION: [Prostasin heavy chain]: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.
Protein: BCHD_HELMO
Sequence: MKVNTLPLAAITGQEAVKLALTLAAVDPGLKGVAIAGRRGTGKTVLARGLRHLLPPIDQLEGCPCHCNPAEPHSWCNRCRERFTEESGLSDSEVPVVQRNAPFSEVPLGATEDRLLGAIDVEQSLAGGVRAWQPGLLGEANRGVLYIDQLNLLDDGLVNSLFDAMSGTCRLEREGISVQYPSNFVLIGTYDPDEGGLRGHLADRIAMHVSSGVIVDLEQRLEIMRRQELFSEAPEDFFDLYNDEQEQTLRRIEKARTVLPQVTISEAQTLYLIGQSLKRGVPGHRADLFSVRLAKAHAAWQGRTAVEPIDLAVAVEFVIKPRQTVDLPDEEEQMQPPPPPPPPPPPPEPDKPDDPETPPDEAPKDEQTLQLPEEFFFDAEEVPMEDELLSLQNKVQRQARGGAHGKQKSLERGRYARALLPPPGKNSRVAVDATLRAAAPYQRQRRESGQYGDRQVIVTNSDIRAKQFVRKSGALIIFVVDASGSMAFNRMSSAKGAVSVLLNEAYVNRDKVALIIFRGQQAETLVPPTRSVELAKKRFDQVPVGGGSPLAGAIAQAIEVGVNSIGSDVGQVIITLITDGRGNVPMDPQAGPKNREQLNEEILALSRLVPENGFSMLVIDTANKFTSTGFAKKIADAAFAQYYYLPKMTAASLAETVKSGVHALRK
What is the function of this protein?
Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.
What are the official names of this protein?
Magnesium-chelatase 67 kDa subunit, Mg-chelatase subunit D, Mg-protoporphyrin IX chelatase.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunits D/I family.
Protein: S39AC_MOUSE
Sequence: MCFWTNLSVWMILLSHSLSLVSSTETGKTLTQNNSRAGSQGLLEVLRVLSAGDHWSLNHPQSLIKILLERTGCPQRTDWTQGDCKLCLEADALLLTAGGNLEDELREEVVQRVSLLLLYYIIHQEEICSSKLNMSNREYEFYLHSLLGLRQDEDSYFLSEKETDDILAFTRKYFGTSSSQCMETKILQRESGIQGSNGADEKTLPQLAATIIALSLQGVCLGRKALPSPDDFTEYIFSFLNSTNTLHLSEIEQLLNMLTTRRTCAKEDKYLHQYQRKQNTEEHSLRDPKTSTAMDKESDDHSPSWDQACFSARQLVEIFLQNHSSLSISKEDFKQLSPGIIQQLLSCSCQMPKDQQAKPPPTTLEKYGYSTVAVTLLTLGSMLGTALVLFHSCEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAEFGHFHESQSPIWKLLGLLGGIHGFFLIEKCFILLVSPNTKGLPLVNEHVGHTHHLGLNPELNDQSSGGKSISTIQLKGPEDSQTTVLPIGNVPASNRNGKTISLLAIMILVGDSLHNFADGLVIGTAFSSSLESGVTTTIAILCHEIPHEMGDFAVLLSSGLSVRTAILMNFLSALTAFAGLYIGLSVSADPRVQDWILTVTAGMFLYLSLVGMLPEMTHVQTQRPWMTFLLQNVGLVLGWFSLLLLAVYEQNIKI
What is the function of this protein?
Uniporter that promotes Zn(2+) import from the extracellular space to the cytoplasm across the cell membrane (PubMed:23716681, PubMed:35065654).  The transport activity is temperature dependent (PubMed:23716681).  May play a role in neurulation and neurite extension (PubMed:23716681).  May play a key role in maintaining intracellular zinc content at levels that reduce the inhibitory effects of rises in oxidative stress on spermatogonia and spermatozoa viability during spermatogenesis (PubMed:35065654).
What are the official names of this protein?
Zinc transporter ZIP12, Solute carrier family 39 member 12, Zrt- and Irt-like protein 12, ZIP-12.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SLYA_ECOHS
Sequence: MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG
What is the function of this protein?
Transcription regulator that can specifically activate or repress expression of target genes.
What are the official names of this protein?
Transcriptional regulator SlyA.
What is the protein family that this protein belongs to?
Belongs to the SlyA family.
Protein: TAT3B_XENLA
Sequence: MARSVVLVDCHWHLTASEFDHDIGSVLEDAKTIGLCALVAVAEHSGEFEKVIELSRRNAGLVFPCLGVHPVQGSATGPQRSATLQDVEDALPMIEQYRDELVAIGEVGLDFTPRIACTDDQKEEQRNVHSRSAGRPTINLLRDQGAEKVLLHAFDGKPSVAMEGVKAGFYFSIPPSIIRSEQQKLVKQLPLENMCLETDSPALGPEKQVRNEPKNILHSAEYIARVKGISLEEVIEITTKNALKVFPRLCHVLPK
What is the function of this protein?
Putative deoxyribonuclease.
What are the official names of this protein?
Putative deoxyribonuclease tatdn3-B.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL27_THET8
Sequence: MAHKKGLGSTRNGRDSQAKRLGVKRYEGQVVRAGNILVRQRGTRFKPGKNVGMGRDFTLFALVDGVVEFQDRGRLGRYVHVRPLA
What is the function of this protein?
Found on the solvent side of the large subunit.
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: GATA_ROSCS
Sequence: MTPLYQLTVAQAREMLARGEISSLELTDALLTRIAAVEPKVRAFLVVDAAGARAQARAADARRAAGDASPLLGIPMGIKDVISTQGLRTTCASKMLENYTPVYDATAVARLKAAGAVILGKLNCDEFAMGSSTENSAFQQTRNPWNLERVPGGSSGGSAAAVAAGEAPAALGTDTGGSIRQPAALCGITGLKPTYGRVSRYGLVAFASSLDQIGPMARTVRDCAIVLRVIAGADPFDATCTDYPAPDYEAALTGDIRGLRIGVPREYFVAGMQPDVEAAVRTAIEVLREQGAEVCEISLPHTPYALPVYYLIAPAEASANLARFDGVRYGLRVPGESYFDELERTRGAGFGPEVRRRIMLGTYALSAGYYDAYYKRAQQVRTLIRRDYQQAFEQVDVIAAPTTPTVAFKIGAHTDDPLAMYLEDVCTLPLNLAGLPGLVVPCGFAEGLPIGLQLIGRAFDEESLLRVGDAYQRVTDWHTRMPEVREDGSA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: MORF8_ARATH
Sequence: MATHTISRSILCRPAKSLSFLFTRSFASSAPLAKSPASSLLSRSRPLVAAFSSVFRGGLVSVKGLSTQATSSSLNDPNPNWSNRPPKETILLDGCDFEHWLVVVEPPQGEPTRDEIIDSYIKTLAQIVGSEDEARMKIYSVSTRCYYAFGALVSEDLSHKLKELSNVRWVLPDSYLDVRNKDYGGEPFIDGKAVPYDPKYHEEWIRNNARANERNRRNDRPRNNDRSRNFERRRENMAGGPPPQRPPMGGPPPPPHIGGSAPPPPHMGGSAPPPPHMGQNYGPPPPNNMGGPRHPPPYGAPPQNNMGGPRPPQNYGGTPPPNYGGAPPANNMGGAPPPNYGGGPPPQYGAVPPPQYGGAPPQNNNYQQQGSGMQQPQYQNNYPPNRDGSGNPYQG
What is the function of this protein?
Involved in organellar RNA editing.  Required for the processing of numerous RNA editing sites in mitochondria and plastids (PubMed:22566615, PubMed:23818871).  Binds to the plastid RARE1 factor, a pentatricopeptide repeat-containing protein involved in RNA editing (PubMed:22566615).
What are the official names of this protein?
Multiple organellar RNA editing factor 8, chloroplastic/mitochondrial, RNA editing-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the MORF family.
What are the subcellular locations of this protein?
Mitochondrion. Plastid, chloroplast. Note=Dual targeting to mitochondria and chloroplasts.
Protein: SPIT1_MOUSE
Sequence: MAGRRLARASISAVGVWLLCALGLQATEAELPSAPAELPGGAACLSRFTSGVPSFVLDTEASVSNGATFLGSPTARRGWDCVRSCCTTQNCNLALVELQPDGGEDAISACFLMNCLYEQNFVCKFAPKEGFINYLTQELYRSYRELRTRGFGGSRIPRIWMGIDLKVQLQKPLVLNEADNTDWHLLQGDSDVRVERKRPEEVELWGLKEGTYLFQLTRTDSDQPEETANLTITVLTAKQTEDYCLASYKVGRCRGSFPRWYYDPKEQICKSFTFGGCLGNKNNYLREEECMLACKDVQGISPKRHHPVCSGSCHATQFRCSNGCCIDGFLECDDTPDCPDGSDEATCEKYTSGFDELQNIHFLSDKGYCAELPDTGFCKENIPRWYYNPFSERCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREGSIPTVGSAEVAIAVFLVICIIVVLTILGYCFFKNQRKEFHSPLHHPPPTPASSTVSTTEDTEHLVYNHTTQPL
What is the function of this protein?
Inhibitor of HGF activator.
What are the official names of this protein?
Kunitz-type protease inhibitor 1, Hepatocyte growth factor activator inhibitor type 1, HAI-1.
What are the subcellular locations of this protein?
Secreted.
Protein: RS6_AERS4
Sequence: MRHYEIVFMVHPDQSEQVPGMIERYTGAITTAGGTIHRMEDWGRRQLAYPIDKLHKAHYVLMNVEAEQAVIDELETNFRFNDAVIRNMIMRTKHAVTEVSPMAKAKEERFVRRDDERREDTVEAASSEE
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: NHAA_BACFN
Sequence: MTVLRSMKDFSSMNITASILLFVTAIAAAVIANSPAASVYQEFLSHELHFRIGGFNLLSHAGHNLTMIEFINDGLMTIFFLMVGLEIKRELLVGELSSFRKAALPFIAACGGMVVPVVIYSMVCAPGTEGGQGLAIPMATDIAFSLGVLSLLGKRVPLSLKIFLTAFAVVDDIGGILVIAIFYSSHVAYEYLLWAALLYVLLYFIGKKGATNKIFFLVVGVVIWYLFLQSGIHSTISGVILAFVIPAKPQLNVGTYIERIRRIISTFPEMGANNIVLTNQQIAKLKEVESASDRVISPLQSLEDNLHGAVNYLVLPLFAFVNAGVMFSGEGEVIGGVTLAVALGLLAGKFLGIYSFTWLAVKSGLTPMPLGMNWKNISGVALLGGIGFTVSLFIANLSFGSAHPVLLNQAKLGVLSGTVMAGILGYLVLHWVLPKRR
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.