PharMolix/UniProtQA huggingface dataset:
Protein: TERT_TETTS
Sequence: MQKINNINNNKQMLTRKEDLLTVLKQISALKYVSNLYEFLLATEKIVQTSELDTQFQEFLTTTIIASEQNLVENYKQKYNQPNFSQLTIKQVIDDSIILLGNKQNYVQQIGTTTIGFYVEYENINLSRQTLYSSNFRNLLNIFGEEDFKYFLIDFLVFTKVEQNGYLQVAGVCLNQYFSVQVKQKKWYKNNFNMNGKATSNNNQNNANLSNEKKQENQYIYPEIQRSQIFYCNHMGREPGVFKSSFFNYSEIKKGFQFKVIQEKLQGRQFINSDKIKPDHPQTIIKKTLLKEYQSKNFSCQEERDLFLEFTEKIVQNFHNINFNYLLKKFCKLPENYQSLKSQVKQIVQSENKANQQSCENLFNSLYDTEISYKQITNFLRQIIQNCVPNQLLGKKNFKVFLEKLYEFVQMKRFENQKVLDYICFMDVFDVEWFVDLKNQKFTQKRKYISDKRKILGDLIVFIINKIVIPVLRYNFYITEKHKEGSQIFYYRKPIWKLVSKLTIVKLEEENLEKVEEKLIPEDSFQKYPQGKLRIIPKKGSFRPIMTFLRKDKQKNIKLNLNQILMDSQLVFRNLKDMLGQKIGYSVFDNKQISEKFAQFIEKWKNKGRPQLYYVTLDIKKCYDSIDQMKLLNFFNQSDLIQDTYFINKYLLFQRNKRPLLQIQQTNNLNSAMEIEEEKINKKPFKMDNINFPYYFNLKERQIAYSLYDDDDQILQKGFKEIQSDDRPFIVINQDKPRCITKDIIHNHLKHISQYNVISFNKVKFRQKRGIPQGLNISGVLCSFYFGKLEEEYTQFLKNAEQVNGSINLLMRLTDDYLFISDSQQNALNLIVQLQNCANNNGFMFNDQKITTNFQFPQEDYNLEHFKISVQNECQWIGKSIDMNTLEIKSIQKQTQQEINQTINVAISIKNLKSQLKNKLRSLFLNQLIDYFNPNINSFEGLCRQLYHHSKATVMKFYPFMTKLFQIDLKKSKQYSVQYGKENTNENFLKDILYYTVEDVCKILCYLQFEDEINSNIKEIFKNLYSWIMWDIIVSYLKKKKQFKGYLNKLLQKIRKSRFFYLKEGCKSLQLILSQQKYQLNKKELEAIEFIDLNNLIQDIKTLIPKISAKSNQQNTN
What is the function of this protein?
Catalytic component of telomerase, an essential ribonucleoprotein enzyme that copies new telomeric repeats onto chromosome ends by repetitively synthesizing the short telomere-repeat sequence 5'-TTGGGG-3' using an RNA template component TER (PubMed:10944124, PubMed:15696174, PubMed:17322903, PubMed:20713447, PubMed:16462747).  TERT is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme (PubMed:10944124, PubMed:15696174, PubMed:17322903, PubMed:20713447, PubMed:16462747).
What are the official names of this protein?
Telomerase reverse transcriptase, Telomerase catalytic subunit, Telomerase subunit P133.
What is the protein family that this protein belongs to?
Belongs to the reverse transcriptase family. Telomerase subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: GDL5_ARATH
Sequence: MNFSLLSTMLMALSSVCLFFVGYAQQFSGSVAVSALFAFGDSILDTGNNNNLNTLSKCNFFPYGRNFIGGKATGRFGNGRVFSDMIAEGLNVKKLLPAYRDPNLSKNDLPTGVCFASGGSGLDERTARSQGVIWVPDQVKDFKEYIMKLNGVVRDKRKVNAIISNAVYLISAGNNDLAITYPTLMAQYTVSTYTDLLVTWTDNLLKSLYAMGARKFAVLGTLPLGCLPGARHTGGNFGNICLVPINQVAAIFNQKLSAKLNNLHTILPGAKFVYVDMYNPLLNLINNPRASGFIDVADGCCCMPTSPVPCPDASQYVFWDFAHPSEKSYMTIAPKIIEGIKKNLA
What are the official names of this protein?
GDSL esterase/lipase At1g23500, Extracellular lipase At1g23500.
What is the protein family that this protein belongs to?
Belongs to the 'GDSL' lipolytic enzyme family.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPF_CHLT3
Sequence: MRIGIGIDIHQLVEGRKLIIGGVEIPYEKGLKGHSDADVLLHAISDALLGAAALGDIGKHFPDTDPAYKGIDSQLLLKHVRKLLETHGYKPVNVDSMLLLEKPKIAPHVQKMRENIAACLEVDVDAISVKATTNEKIGYVGRGEGALAHAVCLIEKI
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: NU4M_ONCMY
Sequence: MLKILIPTLMLFPTIWLSPAKWLWTTSIAQSLIIALASLSWLKWSSETGWSSSNLYLATDPLSTPLLVLTCWLLPLMILASQSHLSPEPLNRQRAYISLLVSLQTFLVLAFGATEIIMFYVMFEATLLPTLIIITRWGNQTERLNAGTYFLFYTLAGSLPLLVALLLMQNDNGTLSMFTLQYTQPLHLLTWGDKLWWAACLLAFLVKMPLYGVHLWLPKAHVEAPIAGSMILAAVLLKLGGYGMMRMMVMLDPLTKELAYPFIVLALWGIIMTGSICLRQTDLKSLIAYSSVGHMGLVAGGILIQTPWGFTGAIILMIAHGLASSALFCLANTSYERTHSRTMLLARGMQMILPLMTTWWFVASLANLALPPLPNLMGELMIITSMFNWSYWTLILTGLGTLITASYSLYLFLMTQRGPLPSHIIALEPTHTREHLLIILHLIPIVLLILKPELMWGWCF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4, NADH dehydrogenase subunit 4.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: YNG2_CANAL
Sequence: MDTSTVLEKYTQDLSNLPLEVRHLLEEIKSKDVQVSEARKRYQTRDHQLHKFIRTNGTLTKHPKEDQLYSKIEEDMKLVQKLQKEKILLANTALFLISKHLYHFETDIAKLERDELLPPLEHPIELTEVSKDEYAKSLNGFSDSASATPTPRNGSSATPVAETVKKIQKKKLSVKGASSSSAQSSSASRQVKRLRSEEIEDPLPYEGGSLAFNGNVAMSINSAADANGPNGEDADNNLYCFCQRVSFGEMIGCDNEDCKYEWFHWSCVGITSPPKDDEIWYCPDCASKMEKRKKKRKN
What is the function of this protein?
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair.  Involved in cell cycle progression and meiosis (By similarity).
What are the official names of this protein?
Chromatin modification-related protein YNG2, ING1 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the ING family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NADA_HELPJ
Sequence: MPTDNDLKTSIVELLRDLDALLVAHFYQKDEIVELAHYTGDSLELAKIASQSDKNLIVFCGVHFMGESVKALAFNKQVIMPKLSCCSMARMIDSHYYDRSVHLLKEYGVKEFYPITYINSNAEVKAKVAKDDGVVCTSRNASKIFNHALKQNKKIFFLPDKCLGENLALENGLKSAILGINSPEEIKNADVVCYNGFCSVHQLFKLEDIEFYRQKYPDILIAVHPECEPSVVSNADFSGSTSQIIEFVEKLSPHQKVAIGTESHLVNRLKAKRNHQNTFILSSTLAFCPTMNETTLKDLFEVLKAYKNHRAYNAIELKDEVARLAKLALTKMMELS
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROL_ECO55
Sequence: MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQVISEIRSALAQTINC
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase 2, SK 2.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family. AroL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBB_APUAP
Sequence: VQWTAEEKQLITGLWGKVNVADCGAEALARLLIVYPWTQRFFASFGNLSSATAVIGNPMVRAHGKKVLTSFGEAVKNLDSIKSTFAQLSELHCDKLHVDPENFRLLGDILIIVLAAHFSKDFTPEAQQAWAKLVRAVAHALARKYH
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: DEF_MICDP
Sequence: MPSEIAVEKKKLKNPPLQLHYLGDRVLRQPAKRIAKVDDELRQLIRDMLQTMYSKDGIGLAAPQVGIHKQLIVIDLEPDNPANPPLVLINPTIKQVSKEICVAQEGCLSIPNVYMDVKRPEVVEIAYKDENGRPKTLKATDLLARCIQHEMDHLNGVVFVDRVDNSLTLAQELSKNGFSYQAVKPVA
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: TRPD_DECAR
Sequence: MTPQAALQRVIEHREIFHDEMVSLMRQIMSGEVTPVMIAAIITGLRVKKETIGEIAAAASVMRELATPVKVPYDRHFVDIVGTGGDAAHTFNISSTAAFVVAAAGGKVAKHGGRSVSSSSGAADVLEALGANIMLSPEQVAACIDETGFGFMFAPNHHTAMKHVAPVRREMGVRTIFNILGPLTNPAGAPNTLMGVFHPDLVGILVRVMQRLGAERVLVVHGKDCLDEISLGAATMVGELNNGEIREYEIHPEDYGLQMQSLRNLRVGSAAESREMLLGVLGNQPGPAREIVCLNAGAALYVANVADSIGDGIVRAREAIASGAARAKLDQFINATKKFA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: SH3L1_MOUSE
Sequence: MVIRVYIASSSGSTAIKKKQQDVLCFLEANKIGFEEKDIAANEENRKWMRENVPEDSRPSTGYPLPPQIFNECQYRGDYDAFFEARENNAVYAFLGLTAPPGSKEAEAQANQQA
What is the function of this protein?
Appears to function as an adapter protein that bridges proteins together or proteins with mRNAs.  May function as a ubiquitin ligase-substrate adapter.  Additionally, associates with translating cytoplasmic ribosomes and may promote the expression of specific mRNAs.
What are the official names of this protein?
Adapter Sh3bgrl, SH3 domain-binding glutamic acid-rich-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the SH3BGR family.
Protein: RL16_CHLL3
Sequence: MLMPKRVKYRKTQRGRMKGNAGRGTSVAFGSFGLKAIEPAWITSRQIEAARVAMNRYMKRDGKIWIRIFPDKPVSKKAAETRMGSGKGSPEFWVAVVKPGRIMFEADGVPMEVATEAFRLAAKKLPIKTRFIVRPDYEA
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: REXO4_CRYNJ
Sequence: MDKKKAPGQTVASSNWLQLQSTLSTITKEKDVSNSKAHNSRSSQSPSSSLRSSSRIQRKSKHSQGVGQYMGRVEVASTAKTTVSQLRKGKVISNEPCILLEAFSDSPLLHELRHMVLGNHLLSESQKEPGQYLAIDCEMVGVGPNGMENTLARVSIVNYHGAVILDTFVQPREPVTDYRTWISGVKQSDLLGAPQFDEVNKQVANLLHDKILIGHAIDNDLKVLMLTHPGPLTRDTQKYKPLQEIAKNKRPGLKKLSELLLGVQIQTGAHSSVVDARVAMALYRLHKKEWERSVWRQTEAYRSISSVNKPEHVLGKRGHDEKEAEDGEETAGESKRKNRKKSGNGGGRQQFPGGGRKGISSGLDVIVRRNGQRVDENGRGDGTSRRKAGRGEISTFTGGESWWEQPAA
What is the function of this protein?
Exoribonuclease involved in ribosome biosynthesis.  Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5. 8S rRNAs (By similarity).
What are the official names of this protein?
RNA exonuclease 4.
What is the protein family that this protein belongs to?
Belongs to the REXO4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RUVB2_DROME
Sequence: MAETEKIEVRDVTRIERIGAHSHIRGLGLDDVLEARLVSQGMVGQKDARRAAGVVVQMVREGKIAGRCILLAGEPSTGKTAIAVGMAQALGTETPFTSMSGSEIYSLEMSKTEALSQALRKSIGVRIKEETEIIEGEVVEIQIERPASGTGQKVGKVTLKTTEMETNYDLGNKIIECFMKEKIQAGDVITIDKASGKVNKLGRSFTRARDYDATGAQTRFVQCPEGELQKRKEVVHTVTLHEIDVINSRTHGFLALFSGDTGEIKQEVRDQINNKVLEWREEGKAEINPGVLFIDEVHMLDIECFSFLNRALESDMAPVVVMATNRGITRIRGTNYRSPHGIPIDLLDRMIIIRTVPYSEKEVKEILKIRCEEEDCIMHPDALTILTRIATDTSLRYAIQLITTANLVCRRRKATEVNTEDVKKVYSLFLDENRSSKILKEYQDDYMFSEITEEVERDPAAGGGAKRRVEGGGGDAQPMEH
What is the function of this protein?
Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.
What are the official names of this protein?
RuvB-like helicase 2, Dreptin, Drep, Reptin.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CM32_CONAA
Sequence: MMSKLGVLLIICLLLFPLTAVPLDGDQPADRPAERMQVDIPTEHHPMFGAVRGCCGAWACMAGCRPCCG
What is the function of this protein?
Mu-conotoxins block voltage-gated sodium channels (Nav).
What are the official names of this protein?
Mu-onotoxin-like Am3.2.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M family.
What are the subcellular locations of this protein?
Secreted.
Protein: RETO_ESCCA
Sequence: MENKTPIFFSLSIFLSLLNCALGGNDLLSCLTFNGVRNHTVFSADSDSDFNRFLHLSIQNPLFQNSLISKPSAIILPGSKEELSNTIRCIRKGSWTIRLRSGGHSYEGLSYTSDTPFILIDLMNLNRVSIDLESETAWVESGSTLGELYYAITESSSKLGFTAGWCPTVGTGGHISGGGFGMMSRKYGLAADNVVDAILIDANGAILDRQAMGEDVFWAIRGGGGGVWGAIYAWKIKLLPVPEKVTVFRVTKNVAIDEATSLLHKWQFVAEELEEDFTLSVLGGADEKQVWLTMLGFHFGLKTVAKSTFDLLFPELGLVEEDYLEMSWGESFAYLAGLETVSQLNNRFLKFDERAFKTKVDLTKEPLPSKAFYGLLERLSKEPNGFIALNGFGGQMSKISSDFTPFPHRSGTRLMVEYIVAWNQSEQKKKTEFLDWLEKVYEFMKPFVSKNPRLGYVNHIDLDLGGIDWGNKTVVNNAIEISRSWGESYFLSNYERLIRAKTLIDPNNVFNHPQSIPPMANFDYLEKTLGSDGGEVVI
What is the function of this protein?
Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack.  Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
What are the official names of this protein?
Reticuline oxidase, Berberine bridge-forming enzyme, BBE, Tetrahydroprotoberberine synthase.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle. Note=Found in cytoplasmic vesicles that are highly specific and unique compartments serving only alkaloid biosynthesis. The protein composition of these vesicles reveals the presence of only about 20 separable proteins.
Protein: RL25_LAWIP
Sequence: MDNLKTLVVQKRLDLGKGPNRRLHKKNLIPGIFYTSSGKNIPIQLPELPFTKIFSEVGRTTVFNLKIESDKENITHPVIIWELQYYPVKNRFMHVDLYGVELNKPIKIVVPLEFTGTAKGTKVGGKLETYREQLTLIANPLDIPSKITLDISDLDIGKSIYVADLKLPEGVKTSYDTNYAIVSVIMPGGNTATEQEG
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: GET1_ASPFC
Sequence: MLSLILTIFFVHVAIYLVNTVGATTIDTLLWILYLKLPTSTSRNARQQSRLKREVVQLKREMNNTSSQDEFAKWAKLRRKHDKAMDEYEAMNKKLTAQKTSFDWSVKIARWLSTNGLKIFLQFYYSKTPVFALPAGWFPFYVEWVLSFPRAPRGSVSVQVWNSVCATAIAVMAEIVTSMLLQLRSRSASPASTAKAQKAQ
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Acts as a membrane receptor for soluble get3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.
What are the official names of this protein?
Protein get1, Guided entry of tail-anchored proteins 1.
What is the protein family that this protein belongs to?
Belongs to the WRB/GET1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ADH_SCACA
Sequence: MFIAGKNIIFVAGLGGIGLETSREIVKSGPKNLVILDRAPNPAAIAELQALNPKVTVSFYLYDVTVPQSETVKLLKTIFAKLKTIDLLINGAGILDDHQIERTIAVNFTGTVNTTTAIMEFWDKRKGGPGGVVANICSVTGFNSIYQVPVYSASKAAALSFTSSIAKLATITGVTVYSINPGITDTTLVHKFNSWLDVEPHVAEKLLAFPTQTSLACAKNFVKAIEANKNGAIWKLDLGRLDEIEWTKHWDSGI
What are the official names of this protein?
Alcohol dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: P54_ASFL6
Sequence: MDSEFFQPVYPRHYGECLSPTSTPSFFSTHMYTILIAIVVLVIIIIVLIYLFSSRKKKAAAAIEEEDIQFINPYQDQQWAEVTPQPGTSKPAGATTASAGKPVTGRPATNRPATNKPVTDNPVTDRLVMATGGPAAAPAAASAHPTEPYTTVTTQNTASQTMSAIENLRQRNTYTHKDLENSL
What is the function of this protein?
Inner envelope protein involved, through its interaction with host dynein, in the intracellular microtubule-dependent transport of viral capsid toward viral factories (By similarity).  Seems to induce caspase-3 activation and apoptosis (By similarity).  Plays a role in virion morphogenesis by recruiting and transforming the host ER membranes into the precursors of the viral envelope (By similarity).  Involved in virus attachment to the host cell (By similarity).
What are the official names of this protein?
Inner membrane protein p54, pE183L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus envelope protein p54 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass membrane protein. Host cytoplasm, host cytoskeleton. Host endoplasmic reticulum membrane. Note=Detected mainly on membrane-like structures within viral factories. Present in mature extracellular virions. Host DYNLL1 and viral p54 interact at the microtubular organizing center (By similarity). Found in the inner envelope of the virus (By similarity).
Protein: URP2_BOVIN
Sequence: MAGMKTATGDYIDSSWELRVFIGEEDPEAESLTLRVTGESHIGGVLLKIVEEIKRKQDWSDHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAMVAICRLLSIRHPEEMSLLRAPEKEKKKKKEKEPEEEVYDLTKVVLVGGVAPASFRGMPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLLDKTQLHSRWLDSSRCLMQQGIKAGDTLWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYHINKLSQSGEVDEPAGTDSGLDDLDLALSNLEVKLEGSAPTDMLDSLTTIPELKDHLRIFRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGEPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYSSEVQAILAFLSLQRTGGGGGGSGNHPQGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLSEAQLRFIQAWQSLPDFGISYVVVRFKGSRKDEILGIANNRLIRIDLSVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQLTGGHEAF
What is the function of this protein?
Plays a central role in cell adhesion in hematopoietic cells.  Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3).  Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells.  Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs).
What are the official names of this protein?
Fermitin family homolog 3, Kindlin-3, Unc-112-related protein 2.
What is the protein family that this protein belongs to?
Belongs to the kindlin family.
What are the subcellular locations of this protein?
Cell projection, podosome. Note=Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells.
Protein: ANMK_COLP3
Sequence: MINNKTVAEGRYYIGLMSGTSADGIDLALVDFTDKGQQPRLVASFYQSYSAIIADKITSLYQPGSNEIDRAFHLDVELAQLFSQAINALLNQEKLTPEDIIAIGNHGQTIRHRPSGDNPFTLQIGCCQTLATLTGIRVVGQFRRKDMALGGQGAPLVPIFHQQLFTQTTAANFVVNIGGIANITFLPTRDSNQAVLGFDTGPGNALLDDWFTKHHPNSDDCFDKNGAWATTGQVIPLLLEQLMQDDYINSAAPKSTGREYFHLEWLEQQLTAFKEATHSQHETVINHNADIQATLLAFTAQSISDAIMALTAQGKVYLCGGGVHNKALVEALSSRLTASDTVFEINTMQALNIDGDILEAMAFAWLAYAFDQGLDSNLPAVTGASASCTLGSAFLP
What is the function of this protein?
Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P.  Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.
What are the official names of this protein?
Anhydro-N-acetylmuramic acid kinase, AnhMurNAc kinase.
What is the protein family that this protein belongs to?
Belongs to the anhydro-N-acetylmuramic acid kinase family.
Protein: RNC_YERPE
Sequence: MNPIVINRLQRKLGYTFQQQELLLQALTHRSASSKHNERLEFLGDSILSFVIANELYRRFPRVDEGDMSRMRATLVRGNTLAEMAREFDLGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIHTIERLILEWYHSRLEEISPGDKQKDPKTRLQEYLQGRHLPLPSYLVVQVRGEAHDQEFTIHCQVSGLNEPVIGTGSSRRKAEQAAAEQALKQLELE
What is the function of this protein?
Digests double-stranded RNA.  Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S).  Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon.  Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
What are the official names of this protein?
Ribonuclease 3, Ribonuclease III, RNase III.
What is the protein family that this protein belongs to?
Belongs to the ribonuclease III family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBIE_PECAS
Sequence: MASEQEKTADFGFRTVAKDEKEVMVAEVFHSVAAKYDLMNDLMSFGIHRIWKRFTIECSGVRRNQRVLDLAGGTGDLTAKFSRMVGEGGEVILADINASMLKVGREKLRNKGIIDNINYVQANAEALPFPDDFFDCITISFGLRNVTDKNKALRSMYRVLKPGGRLLVLEFSKPVIKQLSTIYDAYSFHILPRIGEAVASDAGSYRYLAESIRMHPDQETLKGMMSDAGFDSVNYFNLTGGIVALHRGFKF
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: RSMG_ZYMMO
Sequence: MTREEALLWLDQHIGISRETVEKLDAFVACLHAEMAHQNLIARSTVDDLWGRHIIDSAQLLPLARKEAAFNKKASPKSWLDLGSGAGFPGIIIAILSEMAVTLVESRRKRVEFLEKAAEAAGTPVTILGQRLENIEPQAFDIITARAFAPLDKLWRLAFPFSHNESLWLLPKGQNARTELEETRKLWQGDTRIEGSVTDPQSAIIVATHIHPKKQKTGKKT
What is the function of this protein?
Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase G, 16S rRNA 7-methylguanosine methyltransferase, 16S rRNA m7G methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAND_ECOL6
Sequence: MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GYAR_PYRFU
Sequence: MKPKVFITRAIPENGINMLEEEFEVEVWEEEREIPREKLLEKVKDVDALVTMLSERIDQEVFENAPRLRIVANYAVGYDNIDVEEATRRGIYVTNTPDVLTNATADHAFALLLATARHVVKGDKFVRSGEWKRKGIAWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAKGFNMRILYYSRTRKSQAEKELGAEYRPLEEVLKESDFVILAVPLTKETMYMINEERLKLMKPTAILVNIARGKVVDTKALIKALKEGWIAGAGLDVFEEEPYYNEELFSLDNVVLTPHIGSATFEAREAMAELVARNLIAFKRGEIPPTLVNKEVIKIRKPGFNEQ
What are the official names of this protein?
Glyoxylate reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPL_STAAN
Sequence: MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGSNQSAEQSAQAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDEYRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
What is the function of this protein?
Required for the development of induced thermotolerance.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpL.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family. ClpL subfamily.