PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_SALPB
Sequence: MLSSQTSSIFTVSRLNQTVRLLLEQEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIAESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQHKQPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANARGECDVLIIGRGGGSLEDLWSFNDERVARAIFANRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEIVSRNQQELLRQIQSAQQRLGMAMDYYLANRSRRFTQIFHRLQQQHPQLRLARQQTALERLRQRMGFALEARIKQATQRQQRVSQRLSQQNPQPRIHRAQSRIQQLEYRLTENIRSRLSEQRERFGNAVTHLEAVSPLATLARGYTVSTTTNGKVLKKIKQVKAGDIMTTRLEDGWLESEVKSVTPGT
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RINT1_HUMAN
Sequence: MLPAGEIGASPAAPCCSESGDERKNLEEKSDINVTVLIGSKQVSEGTDNGDLPSYVSAFIEKEVGNDLKSLKKLDKLIEQRTVSKMQLEEQVLTISSEIPKRIRSALKNAEESKQFLNQFLEQETHLFSAINSHLLTAQPWMDDLGTMISQIEEIERHLAYLKWISQIEELSDNIQQYLMTNNVPEAASTLVSMAELDIKLQESSCTHLLGFMRATVKFWHKILKDKLTSDFEEILAQLHWPFIAPPQSQTVGLSRPASAPEIYSYLETLFCQLLKLQTSDELLTEPKQLPEKYSLPASPSVILPIQVMLTPLQKRFRYHFRGNRQTNVLSKPEWYLAQVLMWIGNHTEFLDEKIQPILDKVGSLVNARLEFSRGLMMLVLEKLATDIPCLLYDDNLFCHLVDEVLLFERELHSVHGYPGTFASCMHILSEETCFQRWLTVERKFALQKMDSMLSSEAAWVSQYKDITDVDEMKVPDCAETFMTLLLVITDRYKNLPTASRKLQFLELQKDLVDDFRIRLTQVMKEETRASLGFRYCAILNAVNYISTVLADWADNVFFLQLQQAALEVFAENNTLSKLQLGQLASMESSVFDDMINLLERLKHDMLTRQVDHVFREVKDAAKLYKKERWLSLPSQSEQAVMSLSSSACPLLLTLRDHLLQLEQQLCFSLFKIFWQMLVEKLDVYIYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHIKEACIVLNLNVGSALLLKDVLQSASGQLPATAALNEVGIYKLAQQDVEILLNLRTNWPNTGK
What is the function of this protein?
Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER.  May play a role in cell cycle checkpoint control (PubMed:11096100).  Essential for telomere length control (PubMed:16600870).
What are the official names of this protein?
RAD50-interacting protein 1, RAD50 interactor 1, HsRINT-1, RINT-1.
What is the protein family that this protein belongs to?
Belongs to the RINT1 family.
What are the subcellular locations of this protein?
Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: RL16_THEVB
Sequence: MLSPKRTKFRKQQRGRMTGVASRGNSIHFGDYALQALEPAWITARQIEAGRRAMTRYIRRGGKIWIRIFPDKPVTMRPAETRMGSGKGSPEYWVAVVKPGRIMYEIAGVTEEVAREAMRLAAYKMPIKTRFLVRNQEEQQQEG
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: ACATN_HUMAN
Sequence: MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALTVAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGSSSWKCKRNN
What is the function of this protein?
Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318).  Negatively regulates BMP signaling (PubMed:25402622).
What are the official names of this protein?
Acetyl-coenzyme A transporter 1, AT-1, Acetyl-CoA transporter 1, Solute carrier family 33 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC33A transporter family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RS18_GLUOX
Sequence: MSETITPDVHEVNPAARRTAVGARRPFYRRRKSCPFSGPNAPKIDYKDVRLLSRFLSERGKIVPSRITAVSAKKQRELAQAIKRARFLALLPYVVN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PYRG_BORPD
Sequence: MTKYVFVTGGVVSSLGKGIAAASLAAILESRGLQVTLLKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFISAKMHKVNNFTTGQIYESVLRKERRGDYLGKTVQVIPHITNEIQDFIARGADAAWNGATDVAIVEIGGTVGDIESLPFLEAARQMSLRLGRNNAAFVHLTLVPFIASAGELKTKPTQHSVQKLREIGIYPNLLLCRADRPIPDDERAKISMFSNVPLDAVISVWDADSIYKIPAMLHKQGVDNIVCEALGLTPPPADLSMWDNLVDALEHPTHQLTIGMVGKYVDLTESYKSLSEALVHAGIHTRSKINIEYIDSEDIETRGTDQLKHLDAILVPGGFGKRGTEGKIAAIRYARENGVPYLGICLGMQLAVIEFARHVAGLGGANSTEFDPSAPHPVVALITEWMDREGKVEKRDATSDLGGTMRKGAQRCPVKPGTRAQAIYGDDVNERHRHRYEVNNVYVPRLEEAGMVISARTPTENLPEMMELPDHPWFVGVQFHPEFTSTPRDGHPLFSSFIEAAIANHARKEA
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: CHED_RALPJ
Sequence: MIEFGKRATPQSAADAVRGDSGMASGMSAGAMATLAQSAASTHAYYDTTFSRRAMKVLPGEYSVTTEDLMLVTVLGSCVSACVRDKTLGIGGMNHFMLPSRNEGESILSPSMRYGTHAMEVLLNQLYKAGAKRERLEIKVFGGAAVLAGMSTLDVGERNGKFVLEFLRNEGLTVAAKDLFDVHPRKVYFVPSTGQIMVRKLRSQNSAAELDSEAQYASKLSKSITTKPASRLQLFT
What is the function of this protein?
Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.
What are the official names of this protein?
Probable chemoreceptor glutamine deamidase CheD.
What is the protein family that this protein belongs to?
Belongs to the CheD family.
Protein: MLTF_SHEDO
Sequence: MIKYLYVILLGLLLSGCQPAEVVEIEASPKAQKRTVLKVGTLYGPQIYVNNSQGETGFDYEMANRFADYLGVSLEMIPFTDRKQLFKALKDNDIDIIAAGIAKTPGRGEQFKMGPTLYKVNQVLVYREGTPEPKDIGTLSGEITVMSNSSSVNTLTQLQKDYPELLWNQVNDKDNEELFALIAKGELNYTISDSNSLLINQRFLPELRAGMILEEKIEVVWLLPPKNSDKLMSQLLAFWHNEQRAGTLEHLNEKYFGHVKRFDYVDTRAFIRAIDNVLPAYRSLFETYSGELDWRKLAAASYQESHWNPNARSKTGVRGMMMLTQPTASYVGVSDRTDAEQSIRGGAIYLKDMIERLPESISDSQRIWFALAAYNIGMGHVEDARRLAVSMDMDPDAWRDVKKVLPLLQQRKYYKQTRYGYARGSQAVHYVDSIRRYYDTLVWVDNQTKKMEVIEAPVEILADKVDANDNIKQSLASDSKTNNTLKPKLGAGQP
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: CKAP2_MOUSE
Sequence: MAESRKRFLGRAARNPLPVTRDLQLPPTRRDQPAFREQRKQKLKEYLLIRKTVFPYKQENQISRDQKMITSEDRVQEGKKVVKLKTEVADKENIESTVEKNCIPLKAGEVTSSEIHNSKDNVQAVQLLSTRDDLPGQTVTLDPACHHKDNKKMQMTAEKPKQDSNVSKKRVLGYYHGQIVQSKINSFRKLPSVKGESLTTTKKLPTTVSKAMKAQSEPANTVSVKASTTAAATKFADAKPVSTASKDTLVRPPIRSLHSSSHGAAKQGLSRPLANVTVRKGMLDKESHRSEPVVSVVKAGSSQAPSRSIASKDAARTDSSNTRLMVKPKDTDQRRYTIAGASVHRSAQLKDTTAERKAQMTEWRTGKGKGLKRPPHSVVTQAEPKGQSENPVGSFWTTMAEEDEQRLFTEKVNKTISECLNLINEGCPKEEILATLNDLIHNIPDAKKLVKYWICLVRIEPITSPIENIISIYEKAILAGAQPIEEMRHIIIDILTTKSQEKVNLGENIEEAHATKEPIQEVNADANVGSGKPGEENEHHGKVEVYEDDQDNKIKDPDLTTPDSKTEAGCIIRYNVSSTPRLQSMKKMQHDKNSTLKELKFLTPVRRSRRIQDKTSRLPAMLKDHDPSVSSLEQLSELGGDAFVCRPNAALCPLFFETDVAEEE
What is the function of this protein?
Possesses microtubule stabilizing properties.  Involved in regulating aneuploidy, cell cycling, and cell death in a p53-dependent manner.
What are the official names of this protein?
Cytoskeleton-associated protein 2.
What is the protein family that this protein belongs to?
Belongs to the CKAP2 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Contrary to the ectopically expressed protein, endogenous CKAP2 does not colocalize with microtubules in G1, S and early G2. At late G2 and prophase after separation of duplicated centrosomes, colocalizes with gamma-tubulin and centrosome-proximal microtubules. From prometaphase through anaphase B, colocalizes with mitotic spindle poles and spindle microtubules. During cytokinesis, absent from midbody microtubules (By similarity).
Protein: RCKA_DICDI
Sequence: MKTSKDSSNSNSNNNNNNNNNNNNNNNNNNGLNGTYSSKSLSPPTSPKQMSGNSIISNSTGNLSSGSGSGSSSGGNKKFINRSFNTFIDFIKKPARRNSKAHNTPPPYPEVDTGFGYFLELDSKPPKPFDEKDDPIHNSTGSTDSWEGDLNSSGGGGKQPQQTQQQSSGENLNNSSDRNNNSNENNQIVDDNSNVFNKGVVVQTVPMTEIGLFPVSLMMAQQRAEHPINVEDIESDVQTCSIPNSKPLYSSLGCSTNSSNSGSSISAPNITFQSFGISPVNNNNNNNNNSNNNSNSNSNSNSNSNNNNNNNNNNNNNNNNNNNNNNNNNSTVNSNNSSLNNSPRYLNSSSSPRSMQHLSSKITTTTTTTTTTTTTTSDDNNGNTNNNISNNNNIINNSNNNSNSNNNNNNNINNTNHKFKTMEKYFSSKENFPIPFPKLKDELGVIIENSSNKGYVGGNKGSEDRRKKIEQKKKQVPAPEMKATKEKFIETITDPTTLNSFRSFMENTQSNENLEFFLEVKRFNTIQDQVLLKHTCDDIWRRFFDDLAVTQLCVESSLKKLINNRRENPTHSMFNEVLDLLLDDIVCDAFRNYISSPFNPEWKSEFKKKFTNNTYSTTTQPINNFNNTNNNNNNNCSTPPNNYSSSPIKQSNINNNNNNASSSNIASSSNVNNNNNNSNGSNTSSSHHRERLDNIKGNRERVDSNGKERSIDNKDILSLLESNLSNHSNSSSNSNGKDKDKDKDKNENTTDNSNNNNNSNNNLNNLIIKNNFNNILQSPQIVSKINEIFKDSNNSQLSISITLDNDEDPTIFHLDESDMESLIEEVVKDNISVHTEISYSDVSIHKWIASGSSGRVYNGQYKGKDVAIKVLGPEVCVHFDLNEFKREVALMSIFKHDNLARCLGAGQYDDKYFHLTEYCHNGSLFSYLRDQRNNISFGQRLHFALGIARGMRYLHSMSIIHRDLKSMNILLTKRLKIKIVDFGTSRVANKYNMTTHVGTQAWMAPEIFTSRTYTNKVDVYSYAIILFEIFTRKSAYDENANINIPNMVMKGERPELPKDMQTSISNIIKKCWQQKPSNRPSFIKIVAYLESIIYPSVSNSLGLVASTSFSSSALWSGQILAQPKN
What is the function of this protein?
Serine/threonine kinase involved in negative regulation of chemotaxis.
What are the official names of this protein?
RGS domain-containing serine/threonine-protein kinase A, RGS domain-containing serine/threonine-protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane. Note=Translocates very rapidly to the plasma membrane upon stimulation by chemoattractant, but no polarized localization to the leading edge in aggregating cells.
Protein: RPOA_STAHJ
Sequence: MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRILLSSLPGAAVKYIEIEGVLHEFSAIDNVVEDVSTIIMNIKKLALKIYSEEDKTLEIDVRDEGEVTASDITHDSDVEVLNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLPIGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKILTEHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQELADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RUVC_ECOLU
Sequence: MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQMSESRLNLARGRLR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: RIMO_ALIB4
Sequence: MKFSTQKPKKTLHMVSLGCTKNLVDSEVMLGRLSDYQLTDDAQNADVIIVNTCGFIDSAKQESINTILSLHEDRKNESVLVMAGCLSERYKEELQKELPEIDVFTGVGDYDRIDELVNEKRSNFTSEVFLASETNERVITGSSYHAYVKLSEGCNQACSFCAIPSFKGKLHSRTLQSLVKEVKALVAKGYVDFSFVSQDSSSFLRDLDIKNGLELLVEEVEKIEGIKTARILYLYPSTTTLSLIDKIADSKVFVNYFDMPLQHITPSMLKIMKRGKGVEQLNELMNHMKSKPNSFVRTTFIAGHPGETEDDFEALCNYVENFKFDRANVFSYSDEEGTTAETRTDKVEQELIDERAEVLGEIISQTTQESLESEVGKTFEVYIDGESEEHEYLLSARKTIWAPSIDGEIYINDNELSEGEQIKFGQIYTVKITELVGDKLLATVIK
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFG_LEPBJ
Sequence: MSTAVAEFKPSEKLLKTRNIGISAHIDSGKTTLTERILFYTNRIHAIHEVRGKDGVGAKMDSMDLERERGITIQSAATYCQWKNHTINIIDTPGHVDFTVEVERSLRVLDSAILVLCGVAGVQSQSITVDRQMRRYNVPRVAFINKLDRTGANPFRVIEQLKEKLKHNAVPVQIPIGLENDLKGVVDLVTMKAYYFEGKDGMDIQEKEIPDDLKELANKKHEELLDAASMFSDELTEALLEGTPTEEMIKKAIRTGTIELKMTPVFMGSAFKNKGVQKLLDGVLDYLASPVDVKNKALDQNNNEEMIVLESNYEKPLVCLAFKLEDGRYGQLTYVRVYQGKLSKGMTIYNMSNNKKHNVGRLCRMHSDEMEDIDSAEAGDIIALFGIDCASGDTFTDGKLKVSMESMFVPAPVISLTIEAKESKHLNNLAKALNRFTKEDPTFQTHVDPESGQTIIKGMGELHLEVYIERMKREYGVELITGAPQVAYRETITSKADFDYTHKKQTGGQGQFGRVAGYMEPIPLEETLDYDFVNKVVGGAIPREYIQSVDKGFKSCLERGSLIGFPIIGVRCVINDGAYHDVDSSDMAFQIAGRYAFRQGFNKANPQILEPIMKVEVDGPSEFQGAILGSLNQRRGMILNTTEEDAYCKTEAEVPLADMFGYSTVLRSSTQGKAEFSMEFSRYAPVPRNVAEELMKKYKVNNKDED
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_YERE8
Sequence: MLKIADTTFTSRLFTGTGKFATAELMLEALRASGSQLITMAMKRVDLQAGNDAILAPLRQLGVRLLPNTSGAKTAQEAVFAARLAREALGTHWVKLEIHPDVKYLLPDPIETLKAAEILVKEGFVVLPYCGADPVLCKRLEEAGCAAVMPLGAPIGSNLGLRTRDFLQIIIAQAKVPVVVDAGIGAPSHALEAIELGADAVLVNTAIAVARSPVKMAHAFRLAVESGELACQAGLGNRQFDRAIATSPLTGFLSQLEEENHV
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLMM_BRUAB
Sequence: MTRKFFGTDGIRGQANSFPMTPEIAMKVGMAVGYIFRRKGQASRAVVGKDTRRSGYMLEKALVAGFTAAGMDVFLLGPIPTPAVAMLCRSLRADIGVMISASHNPFYDNGIKLFGPDGFKLSDQIELQIEAMIEGDMTPFLASHGDVGRAKRVDGDIYRYIEFAKRTLPRNISLNGLRVVVDCANGAGYKVAPAALWELGAEVITINNEPNGININEDCGSTHPIGLMKKVHEVRADVGIALDGDADRVLLVDENGTVIDGDQLMAVIAESWAASNRLEGGGIVATVMSNLGLERFLADRNLTLARTKVGDRYVVEHMREHGFNVGGEQSGHIVLSDFATTGDGLISALQILAVAQEQNKPISDVCRKFQPVPQLLKNVRTTGGKPLENKRVKSAIDEAKERLGGQGRLVIRPSGTEPLIRVMAEGDDRGLVEKVVNDIIDVISSESSAAA
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: AVRP3_PSESH
Sequence: MKIGTQATSLAVLHNQESHAPQAPIAVRPEPAHAIPEIPLDLAIRPRTRGIHPFLAMTLGDKGCASSSGVSLEDDSHTQVSLSDFSVASRDVNHNNICAGLSTEWLVMSSDGDAESRMDHLDYNGEGQSRGSERHQVYNDALRAALSNDDEAPFFTASTAVIEDAGFSLRREPKTVHASGGSAQLGQTVAHDVAQSGRKHLLSLRFANVQGHAIACSCEGSQFKLFDPNLGEFQSSRSAAPQLIKGLIDHYNSLNYDVACVNEFRVS
What is the function of this protein?
Cysteine protease avirulence protein, which is essential during infection of plant cells from cultivar-specific of beans and Arabidopsis thaliana.  The autocleavage of the protein is required for virulence function.  May act by affecting the plant defense system.  In plants lacking R3 or RPS5 resistance genes, it probably impairs the plant defense system and leads to the bacteria multiplication.  In contrast, in plants containing the R3 or RPS5 protein, it is unable to induce disease symptoms, explaining its avirulence name.  The 7 kDa product is required for the type-III translocation from Pseudomonas strains to the plant, but are partially dispensable for effector recognition following in planta expression.  In infected plants, it acts by cleaving the PBS1 protein, which leads to resistance or disease, depending on the presence or absence of RPS5, respectively (PubMed:11952132, PubMed:17277084).  Targets the Arabidopsis kinases PBS1, BIK1, PBL1, PBL2, PBL3, PBL5, PBL7, PBL9 and PBL11 for cleavage in vitro (PubMed:20413097).  Can block recognition of AvrB avirulence factor by plant cells by cleaving Arabidopsis RIPK kinase and suppressing Arabidopsis RPM1 activation.  Cannot block AvrRpm1-induced activation of RPM1 (PubMed:25625821).
What are the official names of this protein?
Cysteine protease avirulence protein AvrPphB.
What is the protein family that this protein belongs to?
Belongs to the peptidase C58 family.
What are the subcellular locations of this protein?
Secreted. Host membrane. Note=In infected plant cells, it is membrane-associated.
Protein: MACIR_MOUSE
Sequence: MEVDINGDSRSTLTTLPLPVAEGSSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEDSKGEAMPALRAKQLDTGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKPLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMNIKEPADTEVLQYQLQHLTLRGDRVFARNNT
What is the function of this protein?
Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages.  The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis.  May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B.  May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells.
What are the official names of this protein?
Macrophage immunometabolism regulator.
What is the protein family that this protein belongs to?
Belongs to the UNC119-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium. Note=Localizes to the transition zone and proximal cilium in addition to being found throughout the cytoplasm.
Protein: GLGA_ECO5E
Sequence: MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTVHNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
What is the function of this protein?
Synthesizes alpha-1,4-glucan chains using ADP-glucose.
What are the official names of this protein?
Glycogen synthase, Starch [bacterial glycogen] synthase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
Protein: EXOW_RHIME
Sequence: MAKLTVVIPYYQKEPGILRRALASVFAQTLEDFHVLVIDDESPYPIADELAGLAQEERERITVIRQPNGGPGGARNTGLDNVPADSDFVAFLDSDDVWTPDHLLNAYQSMTRFDADCYWASITGGDAFYYHFGVADLEKSETVTRLSESPLVVELPELQDVMLKNWSFLHMSCMVIGRKLFEKVRFEATLKLAAEDVLFFCDCVLASKRVVLCDAAGAVRGEGLNIFHSIDNDSPQFLKQQFNTWVALDTLEGRYRNRPKAMEAIRSYKHTARRQALWSQARRIKRRKLPQFDLLARWLWRDPRLIGSAAELAVGKLSR
What is the function of this protein?
Glycosyltransferase required for the synthesis of succinoglycan (EPS I).  Needed for the addition of the seventh sugar (glucose), catalyzes the formation of a beta-1,3 linkage between the seventh and eighth sugar.
What are the official names of this protein?
Succinoglycan biosynthesis protein ExoW.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MUTL_YERPN
Sequence: MPIQILPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDIDIERGGAKLIRIRDNGCGISKDDLALALARHATSKISSLEDLEAILSMGFRGEALASISSVSRLILTSRTAEQSEAWQAYAEGRDMAVTIKPAAHPVGSTLEVLDLFYNTPARRKFMRTEKTEFGHIDEVVRRIALARFDVAINLNHNGKLIRQYRAAPDPAQHERRLASICGPAFLQHALAIAWQHGDLNIHGWVADPAASHTLSEMQYCYVNNRMMRDRLINHAIRQAYQDRLNDAQQPAYVLYLDIDPHQVDVNVHPAKHEVRFHQARLVHDFIYQAVTAVLQQTNAPILNISEEGEVDAPRWQQENRVAAGTNKYAQPEAAKSSAAEQAVARERSSARERAAPAYKEDHPYQKQQGELYRQLLQPSAAAKPATSPAAIPASSVSSPSIPVQRITQAEEPLHGDNYSFGRVLTVFPPCYALIEYQGGVALLSLAVAERWLKQAQLSPPEEGLRPQPLLIPLKITLDKNEIAACQNHEKLLITMGIELSVEQGRATLRAVSLPLRQQNLQKLIPELLGYLSQHEEISPDTLATWLARHLGSEHEVWNVSQAIQLLTEVERLCPQLVQSPPAGLLQPIDIKAALATLTHE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.