PharMolix/UniProtQA huggingface dataset:
Protein: ARLR_STAA3
Sequence: MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGLDKALSHYYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITAKSDTYDKVAGLDYGADDYIVKPFDIEELLARIRAILRRQPQKDIIDVNGITIDKNAFKVTVNGAEIELTKTEYDLLYLLAENKNHVMQREQILNHVWGYNSEVETNVVDVYIRYLRNKLKPYDRDKMIETVRGVGYVIR
What is the function of this protein?
Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence.
What are the official names of this protein?
Response regulator ArlR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_CYTH3
Sequence: MSGIIGKKVGMTSVYDAVGNYVPCTVIEAGPCVITQIKTVETDGYKAVQLAFDDKKEKSTTKPLLGHFKKAGVSPKRKLVEFKGFENELTLGQSLAAQDVFVEGDFVDVVGTAKGRGFQGVVKRHGFGGVGGQTHGQHNRARHAGSIGACSFPARVFKGTRMAGRMGNNRVKIQNLQILKVYPEHNLLVVSGSVPGSKNSYVLIEK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y1796_ARCFU
Sequence: MLRFLEVVSEHIKNLRNHIDLETVGEMIKLIDSARSIFVIGAGRSGYIAKAFAMRLMHLGYTVYVVGETVTPRITDQDVLVAISGSGETTSVVNISKKAKDIGSKLVAVTGKRDSSLAKMADVVMVVKGKMKQERDEILSQLAPLGTMFELTAMIFLDALVAEIMMQKHLTEKDLEARHAVLE
What are the official names of this protein?
Uncharacterized protein AF_1796.
What is the protein family that this protein belongs to?
Belongs to the SIS family. PHI subfamily.
Protein: THIG_MOOTA
Sequence: MADELIIGDKALTSRLFIGTGKFASHEIMGQAVSQSGAQVVTVALRRVDLDNPQESELKFIPAGCVLMPNTSGARTAEEAVKIARIARAAGCGNWVKIEVVTDQRYLLPDNYETVKATEILAKEGFVVLPYMNPDLMVAKRLKEAGAAAIMPLGAPIGSNRGLKTREMIRILIEEIDLPIIVDAGIGKPSEAMEAMEMGAAAVLVNTAIATARDPVAMARAFSMAVEAGRMAYLAGLAPTREYAEASSPLTGFLV
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCP_IRV22
Sequence: MSMSSSNITSGFIDIATFDEIEKYMYGGPTATAYFVREIRKSTWFTQVPVPLSRNTGNAAFGQEWSVSISRAGDYLLQTWLRVNIPPVTLSGLLGNTYSLRWTKNLMHNLIREATITFNDLVAARFDNYHLDFWSAFTVPASKRNGYDNMIGNVSSLINPVAPGGTLGSVGGINLNLPLPFFFSRDTGVALPTAALPYNEMQINFNFRDWHELLILTNSALVPPASSYVSIVVGTHISAAPVLGPVQVWANYAIVSNEERRRMGCAIRDILIEQVQTAPRQNYVPLTNASPTFDIRFSHAIKALFFAVRNKTSAAEWSNYATSSPVVTGATVNYEPTGSFDPIANTTLIYENTNRLGAMGSDYFSLINPFYHAPTIPSFIGYHLYSYSLHFYDLDPMGSTNYGKLTNVFVVPAASSAAISAAGGTGGQAGSDYAQSYEFVIVAVNNNIVRIENSLVRNRRRWSREGPMVMVC
What is the function of this protein?
Major capsid protein that self assembles to form an icosahedral capsid.  Represents around 50% of the total virion protein mass (By similarity).
What are the official names of this protein?
Major capsid protein, MCP, P50.
What is the protein family that this protein belongs to?
Belongs to the NCLDV major capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: CCND2_RAT
Sequence: MELLCCEVDPVRRAVPDRNLLEDRVLQNLLTIEERYLPQCSYFKCVQKDIQPYMRRMVATWMLEVCEEQKCEEEVFPLAMNYLDRFLAGVPTPKTHLQLLGAVCMFLASKLKETIPLTAEKLCIYTDNSVKPQELLEWELVVLGKLKWNLAAVTPHDFIEHILRKLPQQKEKLSLIRKHAQTFIALCATDFKFAMYPPSMIATGSVGAAICGLQQDEEVNALTCDALTELLTKITHTDVDCLKACQEQIEAVLLNSLQQFRQEQHNGSKSVEDPDQATTPTDVRDVDL
What is the function of this protein?
Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition.  Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase.  Hypophosphorylates RB1 in early G(1) phase.  Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals.
What are the official names of this protein?
G1/S-specific cyclin-D2, Vin-1 proto-oncogene.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. Cyclin D subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Nucleus membrane. Note=Cyclin D-CDK4 complexes accumulate at the nuclear membrane and are then translocated into the nucleus through interaction with KIP/CIP family members.
Protein: RR14_ANGEV
Sequence: MAKKSLIEREKKRKILVQKYKFIRQSLKNEIKDASSLEEILAIHKELQSLPRNSAPTRLHRRCFLTGRPRSNYRDFGLSRHVLREMAHTCLLPGVTKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles.
What are the official names of this protein?
30S ribosomal protein S14, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: PA_I40A0
Sequence: MEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKLAAICTHLEVCFMYSDFHFINEQGESIIVELGDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFRQSERGEETIEEKFEITGTMRKLADQSLPPNFSCLENFRAYVDGFEPNGYIEGKLSQMSKEVNARIEPFFKTTPRPIRLPDGPPCSQRSKFLLMDALKLSIEDPSHEGEGIPLYDAIKCMRTFFGWKEPYVVKPHEKGINPNYLLSWKQVLAELQDIENEEKIPKTKNMKKTSQLKWALGENMAPEKVDFDDCKDVSDLKQYYSDEPELRSLSSWIQNEFNKACELTDSVWIELDEIGEDVAPIEHIASMRRNYFTAEVSHCRATEYIMKGVYINTALLNASCAAMDDFQLIPMISKCRTKEGRRKTNLYGFIIKGRSHLRNDTDVVNFVSMEFSLTDPRLEPHKWEKYCVLEIGDMLLRSAIGQVSRPMFLYVRTNGTSKIKMKWGMEMRRCLLQSLQQIESMIEAESSVKEKDMTKEFFENKSETWPIGESPKGVEEGSIGKVCRTLLAKSVFNSLYASPQLEGFSAESRKLLLIVQALRDNLEPGTFDLGGLYEAVEECLINDPWVLLNASWFNSFLTHALR
What is the function of this protein?
Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits.  The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching.  It consists in the hijacking and cleavage of host capped pre-mRNAs.  These short capped RNAs are then used as primers for viral mRNAs.  The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.
What are the official names of this protein?
Polymerase acidic protein, RNA-directed RNA polymerase subunit P2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses PA family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=PB1 and PA are transported in the host nucleus as a complex.
Protein: MURI_OENOB
Sequence: MDNRGIGYIDSGLGGLTVVREALKQLPNESVYFVGDEARMPYGPRPTVEIQKFTLQMADFLVKKHNIKALVVACNTATAQALPQLRAYLEIPVIGVISAGALAGINATRNLHVNVIGTQSTVESKAYYDQLIALNSDLVIEQKALPEFVQLVESDMAGTPKGKQIVYQAIHNWMEEKNDGKKSDTLVLGCTHFPILKKEIQAAVDKNVAVVDPASEEILQTAEIMRKNNAFHDSKNINHHEKDVFYTTGNIGRFSKFTREWLNKSNLTIKELHIDQKGLKE
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: PYRF_RHIFH
Sequence: MSTSARDRLIVGLDLPTIAEAERIVSTLGDDVAFYKIGYQLAFAGGLEFARDLAASGKKVFLDMKLLDIDNTVAKGVENIVRMGMSMLTLHAYPKAMKAAVDAAKGSDLCLLGVTVLTSMDAQDVIDAGYGSDPHTLVLRRAEQARAAGMGGIVCSAEEATAVRRIIGAEMAVVTPGIRPTGAEKGDQKRVMTPAEAIRAGSSHLVVARPIVKAADPLSASRAILAEMEGVLSA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: SUB5_ARTBE
Sequence: MTGFFTILSFSLAALSVTNAAQILSVPKGAEVVPNGYIVVMKDDTSQQDFSSHRVWISSIHHNMTRRGLDGAGVKQTYDFDHLRGYSGIFDEDTIKDISNDPKVAFVEPDAIISQHVVVQQRKAPWGLSRLSNRRGGRNYVFDSSAGSGVWAYVVDSGVDVRHAEFQGRAVWGSNLVDNKNSDGTGHGTHVAGTIAGKTYGIAKKAKVVAVKVLNSEGKGPTSGIIAGINWSIRHARKHGMLQKSVLNMSLGGTYSAGLNHATAQAIKAGMFVSVSAGNDNINSNGNSPASERSVCTIAASTENDGKASFSNWGPAVDLYAPGHNILSARPGGGSQTMSGTSMAAPHAAGVAAYLIAKEGIPGNRACLRLKQLSQPTIRNPGPDTTTRLLYNGSGR
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: ORYB_ORYSJ
Sequence: MAARAAAAAFLLLLIVGAATAAPDMSIISYNAEHGARGLEEGPTEAEARAAYDLWLAENGGGSPNALGGEHERRFLVFWDNLKFVDAHNARADERGGFRLGMNRFADLTNEEFRATFLGAKVAERSRAAGERYRHDGVEELPESVDWREKGAVAPVKNQGQCGSCWAFSAVSTVESINQLVTGEMITLSEQELVECSTNGQNSGCNGGLMDDAFDFIIKNGGIDTEDDYPYKAVDGKCDINRENAKVVSIDGFEDVPQNDEKSLQKAVAHQPVSVAIEAGGREFQLYHSGVFSGRCGTSLDHGVVAVGYGTDNGKDYWIVRNSWGPKWGESGYVRMERNINVTTGKCGIAMMASYPTKSGANPPKPSPTPPTPPTPPPPSAPDHVCDDNFSCPAGSTCCCAFGFRNLCLVWGCCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPLSVKALKRTLAKLNTA
What is the function of this protein?
Probable thiol protease.
What are the official names of this protein?
Oryzain beta chain.
What is the protein family that this protein belongs to?
Belongs to the peptidase C1 family.
Protein: SPEE_ECO27
Sequence: MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTNQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALPQYLQDALASQPS
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOB_CLOTE
Sequence: MVHPVQVGKRTRMSFSKIKEVCEMSNLIEVQLDSYEWFLQEGLQEVFDDINPIQDYTGNLSLEFVGYKLDMENIKYSVEECKERDATYAAPLKVSVRLINKETGEIKEQDVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDVSLDKSGKELFSATVIPNRGAWLEYETDSNDIIYVRIDKTRKLPISILIRALEYGSDLEIIDYFGEDERLKASIEKDNTKTKEEALLEIYKRLRPGEPPTVDSAMSLIGSLFFDAKRYDLSRVGRYKFNKKLALHLRIANQISAQDIVNPATGEIVVQEGEKIDRDKAIEIQNSGINSVDIQLDDKVLRVIGNNFVDIKSFVKFDIDDLNIKEYVHYPTLKEILDNYSDEEMIKEQIKKNINVLIPKHIIRDDIMSTISYEIGLPYGIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQDSITPQALINIRPVTASIKEFFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATYAKVNEYGFIETPYRKVDKATGVVTHDIIYMTADEEDHYLIAKANEILNDDGTFIDDKITVRDQEDVLVVPKEEVDFMDVSPRQLVSVATAMIPFLENDDASRALMGSNMQRQAVPLLKPEAPIVGTGIEYKAAVDSAVLPKAKKPGVVTYVSASEIRVKKDKPDSNGDVDKYKLLKFKRSNQGTCINQKPLVSKGDKVDTKTVLADGPSTDLGEIALGKNIRMGFITWEGYNYEDAMLISEELVREDVFTSIHIEEYEAEARDTKLGPEEITRDIPNVGEDALKDIDERGIIRIGAEVRSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGEAGIIVDVKVFTRENGDELSPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFLPDGRPLQICLNPLGVPSRMNIGQVLEVHLGLAASKLGWHVATPVFDGATEPEIVECLEKAGYEGDGKTVLYDGRTGEPFDNRVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRVKTYEAIVKGENIPEPGVPESFKVLIKELQALCLDVKVLNDDNEEIAIKELADDDMVELEVNIEGSEDYTEPKQPNDNYLEEEENKDKESDYDEDLNFDDLTKGLQLDDFNDEH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: DAPH_CLOAB
Sequence: MNYDLTNPYEIAKYIKEAKKTTPLKVYVNGNLGDCTADDIDCFGTDDFYILFGESDKISAFLESHGDKIKKFKIEQDRRNSAIPLIDMTKIDARIEPGAIIRDKVSIGKNAVIMMGAVINIGSEIGEGAMIDMNAVVGARGKIGKRAHIGAGAVIAGVLEPPSKSPCEIGDDVLIGANSVILEGVKIGANSVIAAGSVVVEDVPSGVVVAGTPARIIKEVDDKTKDKTQIMDDLRK
What is the function of this protein?
Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate.
What are the official names of this protein?
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, Tetrahydrodipicolinate N-acetyltransferase, THP acetyltransferase, Tetrahydropicolinate acetylase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. DapH subfamily.
Protein: PFKA_CALS4
Sequence: MKTIGILTSGGDAPGMNAAIRAVVRTGIYYGLKVKGIMRGFAGLVEDEVIDLGLSSVGDIIQKGGTILRTARCEEFKQKEVRKKAYETLQKHGIEGLVVIGGDGSFRGAQLLSEEWNVNTICIPGTIDNDIPCTDYTIGFDTACNTVIDAINKIRDTATSHERANIIEVMGRNSGYIALYAGVAGGAEMIILPEVEWSIDELCDKITYGIKRGKLHHIIVLAEGVMSAPELAKMIKERLPKLDLRYTILGHIQRGGAPTVMDRVLASQMGARAVELLLENKTKRVISIRNNQIVDDDIDEALSMKKEFNRKLYELSKILSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS10_ALIFM
Sequence: MQNQRIRIRLKAFDYKLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLTSPHVNKDARDQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: DNAK_THISH
Sequence: MGKIIGIDLGTTNSCVAVMEGDKAKVIENAEGARTTPSIVAFTEDGEVLVGQAAKRQAVTNPKNTLFAVKRLIGRRFEEPEVQKDIKLVPYEIFKADNGDAWVRVRDKKMAPPEISARVLQKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGKIAGLEVKRIINEPTAAALAYGLDKKRGDSKVAVYDLGGGTFDVSIIEIAEVDGEHQFEVLATNGDTFLGGEDFDMRLIDYLVEEFKKEQGIDLKGDPLAMQRLKESAEKAKIELSSSQQTDVNLPYITADASGPKHMNIKVTRAKLESLVEELIKRTIEPCKVALKDAGLSVSDIDDVILVGGQTRMPKVQDAVKNFFGKEPRKDVNPDEAVAVGAAIQAGVLGGEVKDVLLLDVTPLSLGIETLGGVMTKLIEKNTTIPTKATQVFSTADDNQTAVTVHVLQGEREMASANKSLGRFDLTDIPPAPRGVPQVEVMFDIDANGILNVSAKDKATGKQQSIVIKASSGLSDEEVERMVRDAEAHADEDKRFHELVAARNQADNLVHATEKSLKELGDQVEAGEKQAIESALSELREAMKGDNKDEIETRTQKLAEASGKLAERVYAKQSAEGGAGEGAGAEQASAQQDDVVDAEFEEVDDKKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CMOB_VIBCM
Sequence: MFNFANVYQQIAQHPQLQLWLNTLPQQLTDWQAKQHGDLDRWMRNLKKIPVGQPEVIDLKNAVAAHNHQPLAQGEQKKLEAVLKTFHPWRKGPYHLHGIHIDTEWRSDWKWDRLLPHISPLKNRLVLDVGCGNGYHMWRMLGEGAQQVFGIDPSELFLIQFEAVRKLLGDDQRVHLLPLGIEQMPELNAFDTVFSMGVLYHRRSPLDHLLQLKNQLVAGGELILETLVVEGDEHTVLVPFDRYAQMRNVYFFPSALALKVWLEKTGFVDVRIVDENITSLGEQRTTEWMTHNSLPDYVDPQDPSKTIEGYPAPRRAILIAKKP
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: ECFT_LEUMM
Sequence: MNNIMIGRFVPGDSWIHRLDPRTKMIGTFIFIFVMLWSTSWATYAWSAAFVVLAIRLTKQPFRLYWDGLKPIFWLILFTVVLQLFFTPGTPVLLHAGPLKVTIPGIINAIYVMIRFVLIILMSTILTLTTPPTSIANALESLLKPLKKIHVPVAELSLMLSIALRFVPLLMDETQKIMNAQKSRGMSFSTGGPIKRAKAIVPLLIPLFVGALQRALDLANAMEVRGFQDATQRTKYRVLSYGSNDRSAFIGLIGFTIIFIGINFFIK
What is the function of this protein?
Part of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates including 5-formyltetrahydrofolate, pantothenate and riboflavin.  Upon expression of the complex plus FolT in E. coli allows 5-formyltetrahydrofolate uptake; 5-formyltetrahydrofolate is not taken up in the absence of FolT or the EcfA1A2T complex.
What are the official names of this protein?
Energy-coupling factor transporter transmembrane protein EcfT, ECF transporter T component EcfT.
What is the protein family that this protein belongs to?
Belongs to the energy-coupling factor EcfT family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL18_AEDAE
Sequence: MGIDINHKWDRKVRRTKPKSLDVYLRLLVKLYRFLYRRTHKKFNKIILRRLFMSRTNQPPISLSRVAKLMKLRGKDENTIAVVVGTVTNDDRKLYCPKMNVCALRVTEKARERILKWGGKIYTFDQLALVAPTGKNTVLMQGERTAREAFTHFGRAPGVPHSNTRPYVQSKGRKYEKARGRRSSCGFKN
What are the official names of this protein?
60S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL18 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SKP_ECOLI
Sequence: MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSNTLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFEQDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQVK
What is the function of this protein?
Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm.  Required for the efficient release of OmpA from the inner membrane, the maintenance of its solubility in the periplasm, and, in association with lipopolysaccharide (LPS), for the efficient folding and insertion of OmpA into the outer membrane.
What are the official names of this protein?
Chaperone protein Skp, DNA-binding 17 kDa protein, Histone-like protein HLP-1, Seventeen kilodalton protein.
What is the protein family that this protein belongs to?
Belongs to the Skp family.
What are the subcellular locations of this protein?
Periplasm.
Protein: MIAA_LACP3
Sequence: MDKPAKRIVMIVGPTAVGKSDLGVYLAQQLHGEVINGDAYQIYRHMDIGTAKITPEEMQGVPHHLLDIADPTVAYSVAKFKKAATAMIDTVADRQQLPILVGGTGFYLNSLRLNLPLGGKAPPTAIRQRWQVALATNGQSWLWQQLAQRDPDAAQQIAPANTRRVIRALEVGELTGRRFSDQPQPAPLFSTLVIGLTTDRAVLYDRINARVDAMMQAGLLAEVEQLLKTVPADAQAMQAIGYKELVPYLHGQAELANCVALIKQHSRHFAKRQLTYFRNQMPTHWFDLVAHPEDKNAIVTLVQQWLKQR
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NDK_SHESH
Sequence: MAIERTFSIIKPDAVAKNHIGAIYNRFETAGLKIIASKMLHLSKEQAEGFYAEHSERPFFGALVEFMTSGPICVQVLEGENAVLANREIMGATNPAEAARGTIRSDFADSIDENAVHGSDAVASAEREIAYFFSTEELCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATB_PSEU2
Sequence: MFGISFSELLLVGLVALLVLGPERLPGAARTAGLWIGRLKRSFNAIKQEVEREIGADEIRRQLHNEHILSMEDEARKMFAPNQPSENSPEPANPPPAPAAAEAASPVHNQAAHHEIGPAQPAAPKTELSLEKTAKPADAGTPVPAPPAHDSSLPPRAP
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides.  TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
What are the official names of this protein?
Sec-independent protein translocase protein TatB.
What is the protein family that this protein belongs to?
Belongs to the TatB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: TM147_BOVIN
Sequence: MTLFHFGNCFALAYFPYFITYKCSGLSEYNAFWKCVQAGVTYLFVQLCKMLFLATFFPTWEGGIYDFIGEFMKASVDVADLIGLNLVMSRNAGKGEYKIMVAALGWATAELIMSRCIPLWVGARGIEFDWKYIQMSIDSNISLVHYIVASAQVWMITRYDLYHTYRPAVLLLMFLSVYKAFVMETFVHLCSLGSWTALLARALVTGLLALSTLALYVAVVNVHS
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes.  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions.  Also acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane.  Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity.  Regulates LBR localization to the nucleus inner membrane.
What are the official names of this protein?
BOS complex subunit TMEM147, Transmembrane protein 147.
What is the protein family that this protein belongs to?
Belongs to the TMEM147 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: MINE2_SYNWW
Sequence: MLDIINRLLGRENAGSRDIARERLRLVLIHDRASVSPNFLNALKEELIRVIREYMEIDEESLIVDLENEENSVALVANIPIRGFKRAANE
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor 2.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: RS19_BURP6
Sequence: MARSVKKGPFCDAHLLKKVEAAAASRDKKPIKTWSRRSTILPDFIGLTIAVHNGRQHVPVYISENMVGHKLGEFALTRTFKGHAADKKAKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.