PharMolix/UniProtQA huggingface dataset:
Protein: HIS6_CAUVN
Sequence: MLKTRIIPCLDVKDGRVVKGVNFVSLRDAGDPVEQARAYDAAGADELMFLDITASSEGRGLILDVISRTAEVCFMPVSVGGGVRQVSDMRRLLLAGADKVSVNTAAVENPDLIAGGADAFGSQCVVVAIDAKAREDGSGWNVWTYGGRKDTGIDVVEWAAKVVERGAGEILLTSMDRDGAKIGYDIPLLQAVTGAVNVPVIASGGAGKTEHLIEAAREGHAAAVLAASIFHFGEISIGEAKQAMADAGIPVRLDALKGAA
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UTP17_SCHPO
Sequence: MEGPNSMEVGSLEVKKNDKDPWSKTAYLGGRLVSKIPAVYSNDNKFVFLTYDTFIGIFSLITGDCINRIFFPNNLANLLPVAVLLSPENAFELYVIFQSGYVCVHDWSNSELLRTMEISTRVHAASFSGKLLFAVTDTPASDSASSQDRFTLYALSPSTSKEGSSILIPTFVSKFNEFLALDSSLRDNNLATVAVITTDKAIFSLNVPKKKRSQRWIHREHLFNMPQKLTNVSLCGSACAVSDDEGKIHVINDISNEKFNPQILHWHANPLNGLSWALNGEYLLSGGQEGVLVLWQMETSHRQFLPRLGSSILSIATSHDSDSYALHLGDNSLVVIRAVDLAEQIHVSGINSFESKYLTSTGPKNTSKQLQGLVQFSSVSPNGELLLMSSSSFNGHSVSVQEYDLTKDSTIRKFEAARYSYSSVSKNSDDATSLDNGHVGSVAVTSSRNGLYIATIDTWCTNIIDEQQRNVKQTALKFWQFDSVQKTWVLMTRIDNPHGNLEVVTALKMMTSSNRFITVGTDATLRIWALLPGSSAWKCVAIHHFANTHSQASIKQRYGFSKALTCSLDDSIIGFGYGSCMHFINSETLEEISTVDLPHGGQLENAQFLNAEHCVIISQRRLLVWNVISASVQWTLASKFTGLLASSSSGNDFAVIDFNSSYSRLIIFSPDSPKIQSIHIFKTLPVALHYLHGGFVVLDNKSIIHVYAGDLTTKIPSAQLSIDNTSRSLLGDFQKRNVPLLNLENPISGSQGLHYKRLTTDMIHNLFNVPSNSPVNMQAIYNTFSKMAVGEPMESLGTQIATLNTE
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs) (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 17, U3 snoRNA-associated protein 17, U3 protein 17 required for transcription.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: IAA21_ORYSJ
Sequence: MAPPQERDYIGLSPAAAAALATELRLGLPGTAEEAESEGGGGGGTDAAPLTLELLPKGGAKRGFADAIVGGPAGQRREAAGGKAAAAAAEAEEEEEKKKAQAPAAKAQVVGWPPIRSYRKNTMAMSQPALKGKDDGEAKQAPASGCLYVKVSMDGAPYLRKVDLKMYKNYKELSLALEKMFSCFTVGHGESNGKSGRDGLSDCRLMDLKNGTELVLTYEDKDEDWMLVGDVPWRMFTDSCRRLRIMKGSDAVGLAPRATDKSKNRN
What is the function of this protein?
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations.
What are the official names of this protein?
Auxin-responsive protein IAA21, Indoleacetic acid-induced protein 21.
What is the protein family that this protein belongs to?
Belongs to the Aux/IAA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RU2A_EMENI
Sequence: MRLTVELIQNSLSYINPLKDRELDLRDNDISSLGNFPFFPRLRMLLLARNRVRQIQPSLANSIPGLTTLVLTANNIAELADLDPLRNLTKLTHLVLLENPVTRKEYYRLWIIWRIPSVRFLDYQKVKDAERAKAAELFGTATEPTALASKILGVKSRTFDIPSGGAADQPPPEKRLRVKLTDSERKRIEKMIREAKSLQEITRLERELNEGRIPGGALDGAGNDGDQMQL
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
U2 small nuclear ribonucleoprotein A', U2 snRNP A'.
What is the protein family that this protein belongs to?
Belongs to the U2 small nuclear ribonucleoprotein A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FGF14_MOUSE
Sequence: MAAAIASGLIRQKRQAREQHWDRPSASRRRSSPSKNRGLFNGNLVDIFSKVRIFGLKKRRLRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQVMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKAGVTPSKSTSASAIMNGGKPVNKCKTT
What is the function of this protein?
Probably involved in nervous system development and function.
What are the official names of this protein?
Fibroblast growth factor 14, FGF-14, Fibroblast growth factor homologous factor 4, FHF-4.
What is the protein family that this protein belongs to?
Belongs to the heparin-binding growth factors family.
What are the subcellular locations of this protein?
Nucleus.
Protein: AROK_ALIF1
Sequence: MAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFLDSDTVIEERTGADIAWVFDVEGEEGFRKREEGVINDLTQEQGIVLATGGGSVISKESRNRLSARGVVVYLETTIEKQLARTQRDKKRPLLQTDEPREVLEALAKERNALYEEVSDYVVRTDDQSAKVVANQIIQMLEER
What is the function of this protein?
Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
What are the official names of this protein?
Shikimate kinase, SK.
What is the protein family that this protein belongs to?
Belongs to the shikimate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JHD1_EMENI
Sequence: MISATSFVTAIGSRPPRYRTPSPPRRAVEPISPCSTADYRTYRASREISASATSDHVRSTPTDKRPSPADVPASHRSGHGRSSSTIDTLATIALATSPTFTPLTHRPPSDKSNTTLSMFPPETEPVERPAKRPRSERDESSYTQHRSNAFSIARPPAISDSMKTDAELLLNFARPTNLYPPIPSSKRANTDDSYHNHTFHTQAQIKERNASTYWVTNHENVIFNHSAMHNIPPSRMRSQSDGSAAISRPVIEGLRPNTSSSTLPPLAFQEEADSGDRHWDMERKPVLEESQVDFCKPDETVPILSQSQPLKKELDADSNGSSQASCATCNLVRIPVDNEDQDVTWISCDGCKRWFHIVCAGFKNDRETRTVDKFICKTCRPIHGQTTFVRKSSRVRTSIDYAGLNQGLVKSATDSLEHHYIEPIKQNKIRFLPENFPRMRPELVTAEYFEKGNGMTEPIVIPAEFNTHATIPPTNPEFDALVQDAPSQEMFDELLDHLPNVDHETVIDCGQNQLDMVIPQGLTVRTVSELYGPEERVEVIDVKSQHGEDKRWTMQKWADYYESTGDKVVRNVISLEVSQSKLGRLIRRPKIVRDLDLQDAVWPEELKAVGNFPKVQFYCLMSVADCYTDFHIDFGGSSVYYHILKGKKTFFFIPPKDKHLKKYEEWCNSPAQDYTFLGDQTKECYRVDLSEGDTMLIPSGWIHAVWTPENSLVIGGNFLTRLNYGMQIKIAKIEKETKVPMKFRYPFFQKIQWYAVLKYLEEDPVPQSVLAAFSQDENYRFHRKYPIYYEFGERANTEPKGSPYHNSRFYSQAELEGLPDLAKYLLRTALIAGSYLVEGVTADTRNAVKRSIPAMPGEPIDVIRTFGVWIAWKRGNEKAAHWTRPGVVESNAKLSLAEKRPAGRPSRRSERNADNQRTYAERQAVQRLSERPAVDIQKDSAPGDESVAPLANNSPPAATSGIPVPVMNEDTSQKHKTASRGSGLGPKRVACDACRKRRIRCHHKEENNGASGSQMTVSTSSLGHHTPTAQDAASALNSLAAIASGAGFQNGLHSIKGMDRMDASANFATSISATPHGVTLKVGDGSPDGLNSAKKGRSKACDDCRKSKRRCIHDEYGRIDPIKAQERSKPRATSLAKRPRVHEEAAPSSANKRLKQESTSPVAQPVHSSHMDTETPTRAQDSVENGVLDQYPRKSNTQHADGLPAEKALLPDQSSYASPPAFQADAVATKELPATVSKPAAVLVSPPTSLADEMDIHDQVDAGGEHVSVIYTPSSGSRQSSRQPRQVERYMPEVHFAKTAKSTTTTPQTTRRSSFGSSGRKTTPGLSSGSKKSGSRPSSSHGKKSLSPSVEKKAERHAISSAPFGQHGRGSKSEHGTSDVDPDAESLRLIREIQEQEFGLRRRAGRA
What is the function of this protein?
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code.
What are the official names of this protein?
JmjC domain-containing histone demethylation protein 1, [Histone-H3]-lysine-36 demethylase 1.
What is the protein family that this protein belongs to?
Belongs to the JHDM1 histone demethylase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS16_CANAX
Sequence: MSTQSVQTFGKKKTATAVAHVKAGKGLIKINGSPITLVQPEILRFKVYEPLTLVGLDKFQGIDIRVKVTGGGHVSQVYAIRQAIAKGLVAYHQKYVDEASKNELKKIFASYDKTLLVADSRRMEPKKFGGRGARARFQKSYR
What are the official names of this protein?
40S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: FETA_CANLF
Sequence: MKWVVSFFSIFLLNFSESRTMHRNAYGIASILDSSQCSAEMNLVDLATIFFAQFVQEATYKEVSKMVKDILTVIEKSTGSEQPGGCLENQLPAFLEEICHEKEISEKYGLADCCSQREEERHNCFLAHKKAAPPSIPPFQVAEPVTSCKAYEENRDMFMNRYIYEIARRHPFLYAPTILSLAAHYGKIIPLCCKAENAVECFQTKTSLITKELRESSLLNQHICAVMRNFGPRTFRAITVTKLSQKFSKANFTEIQKLVLDVAHIHEECCRGNVLECLQDGEKIMSYICSQQDILSSKIADCCKLPILELGQCIIHAENDGKPEGLSPNLNRFLEERDFNQFSSREKDLFMARFTYEYSRRHTKLAVPVVLRVAKGYQELLEKCSQSENPLECQDKGEEELEKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTPPELMAFTRKMATAAATCCQLSEDRQLACGEGAADLIIGQLCIRHEETPINPGVGQCCSSSYANRRPCFSSLVVDETYIPSPFSADKFIFHKDLCQAQGVALQTMKQQFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEACFEEEGPKLISKTRAALGV
What is the function of this protein?
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin.
What are the official names of this protein?
Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin.
What is the protein family that this protein belongs to?
Belongs to the ALB/AFP/VDB family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDPA_ECOLC
Sequence: MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQAASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y081_BUCBP
Sequence: MDKLYVLVGFILMNILKKVFLSTIFVSIIFCLGILFLVKSNLGLRTIFFLSHYLVPELEVDQLIGTLNNFKLINVKYKSKNILLTIKVLQLNFIVHIFKKFYIDVNLVTCKNVNFFIKNINDVNFKTNGVFPLNLKSKFFSYFFIFFKDIRFYNFTANVDGVELFTNFFSSKGYWNKQFLELEFFKTDVVSINNFYCFDSTNNYCRFNSRNFLVCCRQYLKMLFNYFKKGNFDTFVNIDIANFSCNKIYLEDNKNISISKFFINFRIFKNSVNIKRLFFVFRRMFKVRINGFININQNYINLTINCVNKNEIYGSSSNIKIIIHGLWLSILKINFYIDKININFLIKRILMPEKLIFKCKLRLSNLNSYIHRKNFSYLNNFKLEIFTNSSEYFFQSYSVLNIKDVFPIKFCLLGIGNYKNIFLKLIKFRIFQKKILCNYEWKYCSNRDLVQKFLLNKFFDNLKKTKLLINIKKIILNNDFNEKILLLSSNFLNIRDKYIFTDVHIISGKNSFSMRSDFNSFLNLNVFFSIKDLKFFFPNFDGKFDIDVKIFRSINYYHAICKFIGNKLDFNIFKIVNIKFLIDINSKDFLNTIFLSVTKLFFGNLYVNHVFFKIKNEHDKRYLATICLSSYNNFMRLILDKYFNINVFIQTNVLRKINYFKFYLDSNVNKTVFALISYLFSNYYKKININYVSFFKHSIKSKFVKFLNKFIYVKQIF
What are the official names of this protein?
Uncharacterized protein bbp_081.
What is the protein family that this protein belongs to?
To E.coli YtfN.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PUR5_PROM2
Sequence: MDYKTSGVDIEAGREFVSEIKQAVEGTHTSNVIEGIGGFGGLFRIPIDSFKKPVLVSGTDGVGTKLELAQSKNFHFEVGIDLVAMCINDIITSGAKPLFFLDYIATGKLDKKQLLRVVQGISHGCGENNCSLLGGETAEMPGFYSKNKYDLAGFCVGIVDEDKLINGKKVSENDLIIALKSNGVHSNGFSLVRKIIQNNNQIEKEFEKVSHLSFYDELLKPTKIYNNVIGQILSEDIEIKAMSHITGGGIPENLPRCIPSDFIPYINTNSWEIPILFEFLKKIGSIPEKDFWNTFNLGVGFCLIIDKQFKDRIYNICKDHDIDSWEIGKIVRKDNATISKFLPEILT
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_SORC5
Sequence: MAKKVTGYVKLQLPAGKANPSPPVGPALGQHGVNIMAFCKDFNSRTAAQGDLIIPVVITVYSDRSFTFIMKTPPASVLLKKAAGLETKKKPGAGSKEPNKVKVGKVTQKQLKELAQLKMQDMNTTNLESAMRSMAGTARSMGIDVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: SYA_HALLT
Sequence: MSDLEAEYRLDYFEEEGFERKECPSCGAHFWTRDADRELCGEPPCEDYSFIDDPGFPEAYSLSEMREAFLSFFEEHGHERIDPYPVAANRWRDDVLLTQASIYDFQPLVTSGQTPPPANPLTISQPCIRMQDIDNVGKTGRHTMAFEMMAHHAFNTREEVAEDEYAYHGEVYWKDETVEYCDKLFESLGADLEDITYIEDPWVGGGNAGPAIEVIYKGAELATLVFMCMERDPDGDYEMKDGHTYSFMDTYIVDTGYGLERWTWMSQGTATVYEAVYPDAIDFLKENAGIEHTEAEQKLVHRAAKLSGRLDIDDVDDVEAARGEIADRLDVDVNRLRELVEPLESIYAIADHSRTLAYMFGDGIVPSNVGTGYLARMVLRRTKRLVDEIGIDAPLDELVDMQAERLGYENRDTIREIVRTEERKYRKTLERGSRKVESLADEYAGTDEPIPTEVLLELYDSHGIQPDMVADIAAERGATVDVPDDFYALVADRHEEADGDEAAAERDDRFDDLPETEKLFYDDQGRTEFEAVVLDVFELEEGYDVVLDQTMFYPEGGGQPADRGQLTAGETTVDVVDVQERNGVVLHRTDADPGKGEFVRGQVDGDRRDRLRAHHTATHLIGHAAREVLGNHVRQAGAQKGIDSSRLDIRHFERITREQVKEIERVANALVRDDVPVRQEWPDRNEAESEHGFDLYQGGVPPGTNIRLIHVGDEDVQACAGTHVERTGEIGAVKVLKTEPVQDGVERIVFAAGGAAVEATQRTEDALYDAARALDVDPLDVPETAERFFEEWKGRGKEIESLKEELAAARASGGADAEEVEIGGVTAVIQRLDGDADELRATANAHVDDGKVAVVGSGADGSASFVVGVPDGVDVNAGQVVSELAARVGGGGGGPPDFAQGGGPDADALDDALDAAPDVLRSLQEA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLYB_ASPOR
Sequence: MRVTAILTLATIAIASPTKVLNSRNELARRQATEGCSIGYCTQNGGTTGGAAGDTVTVTDLASLTEAAESETPLTIIVSGNIEGSAKIRVASDKTIYGETGSSITGVGFYIRQVSNVIMRNLKIGQVLADNGDAIGIDESTNVWVDHCDLSGDLSAGKDDLDGLLDITHAAEWVTVSNTYLHDHWKASLVGHSDSNADEDTGHLHITYANNYWYNINSRAPSIRFGTVHIINNYWDSLLGTGVNCRMDAQVLIQSSAFSNCPDEAIFFADSDYTGYAVVDDVDLGGSTNSVPEGTLTASSLPYDAIEALGSAQIAATIPETAGQKL
What is the function of this protein?
Pectinolytic enzyme consist of four classes of enzymes: pectin lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase.  Among pectinolytic enzymes, pectin lyase is the most important in depolymerization of pectin, since it cleaves internal glycosidic bonds of highly methylated pectins.  Favors pectate, the anion, over pectin, the methyl ester (By similarity).
What are the official names of this protein?
Probable pectate lyase B.
What is the protein family that this protein belongs to?
Belongs to the polysaccharide lyase 1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MAL1_DROVI
Sequence: MEEGERWREGHVYQRSSETRKPTNYDRPDSPVTHYVSDTHIVGTLMDELEVETGLITTILIATFNEMRRSHKPNELDDNINWWRHEVFYQIYPRSFKDSDGDGIGDLKGITSKLQYFVDTGITAIWLSPIYKSPMVDFGYDISDYRDIQPEYGTLEDFDALIAKANQLGIKVILDFVPNHSSDEHEWFKKSAAREPGYEDFYVWEDGIPGDNETRLPPNNWVSVFSGSAWQWHEERQQFYLRQFTKGQPDLNYRNPAVVQAMDEVLLYWLQKGVAGFRIDAVIYIYEDEQLRDEPLSGSTSDPNSVDYLEHIYTRNLPECYGLIQHWRQLLDNYTADNPGPVRIMMTEGYADLSLLMNYYEDEDGVQGAHFPFNFDFITELNANSAAPDFVYFIQRWLTYMPPGHSANWVMGNHDNPRVASRYGVGTVDAMNMLMMTLPGIGITYYGEELGMVDYRDISWNDTVDQPACDAGLDNYKWVSRDPERTPMQWSDEKNAGFSTGDSTWLPVHPNYQELNLLTQQEATYSHYKVYQSLIKLRQSRVLRDGSFTAQALNRNVFAIKRELRGQPTLLTVINVSNRTQQVDVSNFIDLPNRLTLLVVGVCSQHRVSERLKPAEVKLSPHEGLVIQLKAR
What are the official names of this protein?
Maltase 1.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: CAS1_HALVD
Sequence: MTKANHHIFADGELSRKEGTLRIDTLEGETKYLPVESIDALYLHGQISFNTRALGLLNKHGVPVHIFGWKDYYRGSYLPKRSQLSGNTVVEQVRAYDNTERRLRIGHRIIEASIHNMRANLQYYSGRRGDFDSVVETLRELKTAVSDTQRIDELRAVEGDARKRYYDCFDSILEAPFRLAKREYNPPSNETNALISFLNGMVYTSCVSAIRKTALDPTVGFVHEPGERRFTLSLDIADIFKPILADRLVFRLVNRKQITTDDFETELAGCLLTEQGRLTVLEEFERSLDQTVQHPRLKRKVSFKTLIQTDVYSLKKHLLTGEPYHATEKWW
What is the function of this protein?
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids).  CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids.  CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).  Acts as a dsDNA endonuclease.  Involved in the integration of spacer DNA into the CRISPR cassette.  Plasmid targeted by CRISPR locus P1 transform wild-type cells very poorly (PubMed:22767603).
What are the official names of this protein?
CRISPR-associated endonuclease Cas1.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated endonuclease Cas1 family.
Protein: SYM_CAMJE
Sequence: MRYITTPIYYVNDVPHLGHAYTTIIADTLARFYRLQGHETRFLTGTDEHGQKIEEAAKLRNSTPQEYADKISFEFKKLWDEFEITYDIYARTTDTRHIEFIKAMFLKMWQKGDIYKDEYEGHYCISCESFFTQSQLINDCSCPDCGKQTRILKEESYFFKLSKYQDKILQWYEEKDPILPKNKKNELINFVQNGLKDLSITRTSFDWGIKLPQEINDDKHIIYVWLDALFIYVSSLDFQNKGENAKFWPAHVHLVGKDILRFHAIYWPAFLMSVDLPLPKFIGAHGWWTKEGEKMSKSKGNVVKPKEVVDAYGSEAFRYFLLREVPFGNDGDFSENMLINRINAELSNEFGNLLNRIIGMSTKYSQGNISKEGVLKFYNAELNQAKEHLNLAVEFLENLQCNRYLEELFKALSVANLAISKYEPWSLIKENKHEQANALVALCANILAKTSLLLSPTLPKSSQKVALALNFEISSANYTKMILDNELLDFKANPCEALFPKVEKALLKQEIKEEPKKEESPKIKIDDFAKIEIKVAKVLDCQNIEGSEKLLKFQLELDDKEIRQVLSGIAKYYKASDLIGKQVCVISNLKKAKIFGHESDGMILSAKSGDKLVLIAPEQLVQNGSLVG
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPPA_ECO55
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVENEWYLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: RSMH_RALP1
Sequence: MTTQTSTGLRHQTVLLDEAVDALIWRDDGIYIDGTFGRGGHSRRILERLGPGGRLVAFDKDPAAITEAGTVEDARFAIEHDSFAQMAQCLDARGIERVAGVLLDLGISSPQIDEGERGFSFRMDGPLDMRMDTTRGITAAQWLAEADERDIARVIRDYGEERFAVQIAKAIVARRGQSGDRGPLDRTSELAALVAQAVKTREKGQDPATRTFQALRIHVNQELADLETGLKAAFDRLEQGGRLVVISFHSLEDRIVKRFMQALARPEQSAAPELRRAPLRAHELPAPQLRLLGRVKPSEAEVSANPRARSAIMRVAERC
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROA_SYNR3
Sequence: MGSVCLSGGGSLHGSVRVPGDKSISHRALLFGAIATGTTTIEGLLPAEDPLSTAACLRAMGVTVSAIDSSGVVRVEGVGLDGLQEPAQVLDCGNSGTTMRLMLGLLAGRHGRHFVLDGDGSLRRRPMARVAQPLAQMGAEIGGREGGNKAPLAIAGQTLSGGTIRTPVASAQVKSALLLAGLTAKGSTTVIEPALSRDHSERMLRAFGAELISEPHAAEGPTAIVRPGAELHGQHVVVPGDISSAAFWLIAALVVPGTELTIENVGINPTRTGILDVLEQMGAPLEVLNQRDVAGEPVADLRVRYSPLKAFEIGGELIPRLVDEIPILSVAALCAEGTSVMRDAAELRVKETDRLAVMARQLRAMGAELEETTDGMVIPGGQRLTGAQVDSETDHRVAMSLAVAALIASGDTSIDQSEAAAVSYPSFWDELARLQRS
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TPS6_ARATH
Sequence: MVSRSYSNLLELASGDSPTFGRMNRQIPRIMAVAGIMSNIDNDSKDTDLSPKDRIIIVANELPIRAQRRVDGNGSGSSSSSTCCSKGWNFSWDENSLLLQLKDGLGDEAIEVIYVGCLKEEIPLNEQEEVYQILLESFKCVPTFLPLDLYTRYYHGFCKQQLWPLFHYMLPLSPDLGGRFDRTLWQAYVSVNKIFADRIMEVINPEDDFVWIHDYHLMVLPTFLRKRFNRVKLGFFLHSPFPSSEIYKTLPIREELLRALLNSDLIGFHTFDYARHFLSCCSRMLGLTYESKRGYIGLEYYGRTVSIKILPVGIHMGQLQSVLSLPETERKVGELIERYGRKGRTMLLGVDDMDIFKGITLKLLAMEQLLMQHPEWQGKVVLVQIANPARGKGKDVKEMQAETYSTVKRINETFGRPGYDPIVLIDAPLKFYERVAYYVVAECCLVTAVRDGMNLIPYEYIVSRQGNEKLDKILKLEANNRNKKSMLVVSEFIGCSPSLSGAIRVNPWNVDAVADAMDSALEVAEPEKQLRHEKHYKYVSTHDVGYWARSFLQDLERSCGEHGRRRCWGIGFGLSFRVVALDQSFRKLSMEHIVSAYKRTKTRAILLDYDDTLMPQGSIDKRPSSKSIDILNTLCRDKGNLVFIVSAKSRETLSDWFSPCEKLGIAAEHGYFLRLRKAVEWENCVAAVDCSWKQIAEPVMELYTETTDGSTIEDKETALVWSYEDADPDFGSCQAKELLDHLESVLANEPVTVKRGQNYVEVKPQGVSKGLIARRMLSMMQERGTLPEFVLCIGDDRSDEDMFEVICSSTEGPSIAPRAEIFACTVGQKPSKAKYYLDDTTEIVRLMHGLASVTDQITPV
What is the function of this protein?
Regulates plant architecture, shape of epidermal pavement cells and branching of trichomes.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6, Trehalose-6-phosphate synthase 6, AtTPS6.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the trehalose phosphatase family.
Protein: FA9_RABIT
Sequence: GVSVSHASKKITRATTIFSNTEYENFTEAETIRGNVTQRSQSSDDFTRIVGGENAKPGQFPWQVLLNGKVEAFCGGSIINEKWVVTAAHCIKPDDNITVVAGEYNIQETENTEQKRNVIRIIPYHKYNATINKYNHDIALLELDKPLTLNSYVTPICIANREYTNIFLNFGSGYVSGWGRVFNRGRQASILQYLRVPFVDRATCLRSTKFTIYNNMFCAGFDVGGKDSCEGDSGGPHVTEVEGTSFLTGIISWGEECAIKGKYGVYTRVSWYVNW
What is the function of this protein?
Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
What are the official names of this protein?
Coagulation factor IX, Christmas factor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_STAAE
Sequence: MTKFIFVTGGVVSSLGKGITASSLGRLLKDRGLNVTIQKFDPYLNVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTAGKVYSHVLKKERRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFIEAIRQIRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMTQDLKDKIALFCDINKESVIECRDADSLYEIPLQLSQQNMDDIVIKRLQLNAKYETQLDEWKQLLDIVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFAKDIDIRWIDSSEVTDENAAEYLADVDGILVPGGFGFRASEGKISAIKYARENNVPFFGICLGMQLATVEFSRNVLGLEGAHSAELDPATPYPIIDLLPEQKDIEDLGGTLRLGLYPCSIKEGTLAQDVYGKAEIEERHRHRYEFNNDYREQLEANGMVISGTSPDGRLVEMVEIPTNDFFIACQFHPEFLSRPNRPHPIFKSFIEASLKYQQNK
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.