PharMolix/UniProtQA huggingface dataset:
Protein: RNPA_CORGB
Sequence: MLPAQHKLNSSMQFRTVMRKGRRAGSKTVVVHLWDSAESLDGTEKQGEVASFGGPRFGLVVSKAVGNAVVRHRTSRRLRHICASIVEKSPELLSPTHHVVIRALAGAGNAPSAELERDIRYGLGKTSRVRTNK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: TRPV1_HUMAN
Sequence: MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFPVDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEIARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKTKGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTADNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQEPECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLNRLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEILSVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVASMVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIEDGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVFIILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKAFRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRSSRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK
What is the function of this protein?
Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli.  Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons.  Involved in mediation of inflammatory pain and hyperalgesia.  Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL.  Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state.  Mild extracellular acidic pH (6. 5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel.  Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin.  Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects.  Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis.
What are the official names of this protein?
Transient receptor potential cation channel subfamily V member 1, TrpV1, Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, Vanilloid receptor 1.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell projection, dendritic spine membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Mostly, but not exclusively expressed in postsynaptic dendritic spines.
Protein: LEU1_SHEPA
Sequence: MSNRVIIFDTTLRDGEQALAASLTVKEKLQIALALERLGVDVMEVGFPVSSPGDFESVQTIAKTIKNSRVCALSRALEKDIDAAAQALSVAEQFRIHTFISTSTIHVESKLKRSFDQVLEMAVGAVKYARRFTDDVEFSCEDAGRTPIDNLCRMVEEAIKAGARTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDQAVISVHCHDDLGLSVANSITAVQHGARQIECTVNGIGERAGNCSLEEIAMILSTRKGELGLETGINAKEIHRTSSLVSQLCNMPVQANKAIVGANAFTHSSGIHQDGMLKAQNTYEIMTPESIGLNRNNLNMTSRSGRHVIKHRMSELGYGEQDYNMDVLYEEFLTLADKKGQVFDYDLEALAFMEAQAETDDHYKLQQLVVHSDSTEGSATATVKVAVNGETITEAATGNGPVDAAYKAVARASGCEINISSYQLSAKGEGQNALGQVDITAKYREQNFHGVGLATDVVEASAKALVHVMNLTWRADKVADCKQRIQQNKRELGGV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: RL27_SALPB
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKRFGGEAVLAGSIIVRQRGTKFHAGTNVGCGRDHTLFAKADGKVKFEVKGPKNRKYISIVAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: FRIML_TREBE
Sequence: MDSQVRQNYHRDCEAAVNRMINMELFASYSYTSMAFYFSRDDVALPGFAHFFKENSDEEREHADKLLTFQNSRGGRIFLQDIKKPERDEWGSGLDALQSSLQLEKNVNQALLDLHKIASDHTDPHMCDFLETHYLNEQVESIKKLGDFITNLSRMDAVKNKMAEYLFDKHTMGGKN
What is the function of this protein?
Stores iron in a soluble, non-toxic, readily available form.  Important for iron homeostasis.  Has ferroxidase activity.  Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).
What are the official names of this protein?
Ferritin, liver middle subunit, Ferritin M.
What is the protein family that this protein belongs to?
Belongs to the ferritin family.
Protein: EFTU_PECAS
Sequence: MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGSARAFDQIDNAPEEKARGITINTSHVEYDTPARHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPFMIVFMNKCDMVDDEELLELVEMEVRELLSQYDFPGDDIPVIRGSALKALEGEAEWEAKIIELAGYLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIVKVGEEVEIVGIKDTVKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQVLAKPGSIKPHTQFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVIA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RDRP_TVCV
Sequence: MAQFQQTIDMQTLQAAAGRNSLVNDLASRRVYDNAVEELNARSRRPKVHFSKAVSTEQTLIATNAYPEFEISFTHTQSAVHSLAGGLRSLELEYLMMQVPFGSLTYDIGGNFSAHLFKGRDYVHCCMPNLDVRDIARHEGHKEAIYSYVNRLKRQQRPVPEYQRAAFNNYAENPHFVHCDKPFQQCELTTAYGTDTYAVALHSIYDIPVEEFGSALLRKNVKTCFAAFHFHENMLLDCDTVTLDEIGATFQKSGDNLSFFFHNESTLNYTHSFSNIIKYVCKTFFPASQRFVYHKEFLVTRVNTWYCKFTRVDTFTLFRGVYHNNVDCEEFYKAMDDAWHYKKTLAMLNAERTIFKDNAALNFWFPKVRDMVIVPLFDASITTGRMSRREIMVNKDFVYTVLNHIKTYQAKALTYANVLSFVESIRSRVIINGVTARSEWDTDKAILGPLAMTFFLITKLGHVQDEIILKKFQKFDRTTNELIWTSLCDALMGVIPSVKETLVRGGFVKVAEQALEIKVPELYCTFADRLVLQYKKAEEFQSCDLSKPLEESEKYYNALSELSVLENLDSFDLEAFKTLCQQKNVDPDMAAKVVVAIMKSELTLPFKKPTEEEISESLKPGEGSCAEHKEVLSLQNDAPFPCVKNLVEGSVPAYGMCPKGGGFDKLDVDIADFHLKSVDAVKKGTMMSAVYTGSIKVQQMKNYIDYLSASLAATVSNLCKVLRDVHGVDPESQEKSGVWDVRRGRWLLKPNAKSHAWGVAEDANHKLVIVLLNWDDGKPVCDETWFRVAVSSDSLIYSDMGKLKTLTSCSPNGEPPEPNAKVILVDGVPGCGKTKEIIEKVNFSEDLILVPGKEASKMIIRRANQAGVIRADKDNVRTVDSFLMHPSRRVFKRLFIDEGLMLHTGCVNFLLLLSQCDVAYVYGDTKQIPFICRVANFPYPAHFAKLVADEKEVRRVTLRCPADVTYFLNKKYDGAVMCTSAVERSVKAEVVRGKGALNPITLPLEGKILTFTQADKFELLEKGYKDVNTVHEVQGETYEKTAIVRLTSTPLEIISSASPHVLVALTRHTTCCKYYTVVLDPMVNVISEMEKLSNFLLDMYRVEAGVQYQLQIDAVFRDSNLFVQTPKSGDWRDMQFYYDALLPGNSTILNEFDAVTMNLRDISLNVKDCRIDFSKSVQLPKEQPIFLKPKIRTAAEMPRTAGLLENLVAMIKRNMNAPDLTGTIDIEDTASLVVEKFWDSYVDKEFSGTNEMTMTRESFSRWLSKQESSTVGQLADFNFVDLPAVDEYKHMIKSQPKQKLDLSIQDEYPALQTIVYHSKKINAIFGPMFSELTRMLLERIDSSKFLFYTRKTPAQIEDFFSDLDSTQAMEILELDISKYDKSQNEFHCAVEYKIWEKLGIDEWLAEVWKQGHRKTTLKDYTAGVKTCLWYQRKSGDVTTFIGNTIIIAACLSSMIPMDKVIKAAFCGDDSLIYIPKGLDLPDIQAGANLMWNFEAKLFRKKYGYFCGRYVIHHDRGAIVYYDPLKLISKLGCKHIRDVVHLEELRESLCDVASNLNNCAYFSQLDEAVAEVHKTAVGGSFAFCSIIKYLSDKRLFRDLFFV
What is the function of this protein?
Is a methyltransferase active in RNA capping and an RNA helicase.  Methyltransferase displays a cytoplasmic capping enzyme activity.  This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus.  Helicase region probably exhibits NTPase and RNA unwinding activities (Potential).  It also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.  May mediate silencing suppression through either inhibition of HEN1-mediated siRNA or siRNA demethylation (By similarity).
What are the official names of this protein?
Replicase large subunit, 183 kDa protein, RNA-directed RNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the ssRNA positive-strand viruses RNA-directed RNA polymerase family.
Protein: TOLB_SHEB9
Sequence: MKILAKWLALAVLLCTTPAKAALDIVITEGVDAARPIAVMPFVWQGPGAAPQAIADVVMSDLVRSGTFKPLDELGLPQRNIGTVAQFQANSWSSVGAEALVLGTVKPYGTDQYLVSFDLIDLVKAQNQALKGPVSATEFLMDSRQTVISAAQFRQYGHRISDIVYEKLTGIRGAFLTRISYVVVNHTQKAPYQLMVADYDGVNEQMLLRSPEPLMSPTWSPDGRRLAYVSFENKKAEIFVQDLYTQVRTKVSSFPGINGAPAFSPDGKSLAITLSKDGQPEIYIIDIATKAIKRITNHYAIDTEPSWYPDGKSLIFTSERGGRPQIYRVELSSGKVSRETFEGEWNLGGSITPDGRSMIFVNRTNGKFNIARMDLSTRFMQVLTSTRLDESPSVAPNGTMVIYGTTYQGKQVLAAVSTDGRFKARLPAGQGEVKSPSWSPFL
What is the function of this protein?
Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
What are the official names of this protein?
Tol-Pal system protein TolB.
What is the protein family that this protein belongs to?
Belongs to the TolB family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RNPA_ECO5E
Sequence: MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVANLDNRALSEALEKLWRRHCRLARGS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: RPOC2_CAPBU
Sequence: MAERANLVFHNKVIDGTAIKRLISRLIDHFGMAYTSHILDQVKTLGFQQATATSISLGIDDLLTIPSKGWLVQDAEQQSWILEKHHHYGNVHAVEKLRQSIEIWYATSEYLRQEMNPNFRMTDPFNPVHMMSFSGARGNASQVHQLVGMRGLMSDPQGQMIDLPIQSNLREGLSLTEYIISCYGARKGVVDTAVRTSDAGYLTRRLVEVVQHIVVRRTDCGTIRGISVSPRNKNRMMSERIFIQTLIGRVLADDIYIGSRCVAFRNQDLGIGLVNRLITFGTQSISIRTPFTCRSTSWICRLCYGRSPTHGDLVELGEAVGIIAGQSIGEPGTQLTLRTFHTGGVFTGGTAEHVRAPYNGKIKFNEDLVHPTRTRHGHPAFLCYIDLSVIIESEDIIHSVTIPPKSFLLVQNDQYVESEQVIAEIREGTYTFHFKERVRKYIYSDSEGEMHWSTDVSHAPEFTYSNVHLLPKTSHLWILSGGSCGSSLILFSIHKDQDQMNIPFLSAERKSISSLSVNNDQTSQKFFSSDFADKKKLGISYYSELNGNLGTSHYNFIYSAIFQENSDLLAKRRRNRFLIPFQSIQEQEKEFIPHSGISVEIPINGIFRRNSIFAFFDDPRYRRKSSGILKYGALKADSIIQKEDMIEYRGVQKFKTKYEMKVDRFFFIPEEVHILPESSAIMVQNYSIIGVDTRLTLNIRSQVGGLIRVERKKKRVELKIFSGDIHFPDKTDKISRHSGILIPPGRGKTNSKESKKFKNWIYVQRITPTKKKFFVLVRPVATYEIADSINLATLFPQDLFREKDNIQLRVFNYILYGNGKPTRGIADTSIQLVRTCLVLNWDQDNKNSALEAVRAFFVEVSTKGLIRDFIRIGLVKSHISYIRKRKNSPDSGFISADHMNPFYPISPKAGILQQSLRQNRGTIRMFLNRNKESQSLLILSSSNCFRMGPFNHVKYHNVINQSIKKNTLITIKNSSGPLGTATQISNFYSFLPLLTYNQISLIKYLQLDNFKYIFQVINSYLIDENGRIFNLDPYSNVVLNPFKLNWYFLHQNYHHNYCEETSTIISLGQFFCENVCIAKKEPHLKSGQVLIVQRDSVVIRSAKPYLATPGAKVHGHYREILYEGDTLVTFIYEKSRSGDITQGLPKVEQVLEVRSIDSISLNLEKRIKGWNKCITRILGIPWGFLIGAELTIVQSRISLVNKIQKVYRSQGVQIHNRHIEIIVRQITSKVLVSEEGMSNVFLPGELIGLLRAERTGRALEEAICYRAVLLGITRASLNTQSFISEASFQETARVLAKAALRGRIDWLKGLKENVVLGGVIPAGTGFNKGLVHCSRQHTNILLEKKTKNLALFEGDMRDILFYHREFCESSISKSDFSRI
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta'', PEP, Plastid-encoded RNA polymerase subunit beta'', RNA polymerase subunit beta''.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family. RpoC2 subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: FCR1_CANAX
Sequence: MSDDHSIHSHTQGLHHIKKKRVGKACDSCRIKKTKCDGKKPCNRCTLDNKICVFTEKKKTKEKKHPSGYVELLEARLDILTRSLEKLIELSRPHLQFIDDIITEEKSVDQEKSSPASSTPNSSSSDHHDDVEEQNSTGVVAPINKVVSYLIKEQGLLKNIPLEWEQGTEIAANFDPNRNLKSSSRLFAEHKGEAFIGSPVTSPQQMPTSNPFRRTSMFKEELESPSSDHYNESIFSQSVDEPYIKKEPNSAQFSKGTFSPQQQQLQQQQQMLNQFSLNTSRDISDIESDSSNKEDGLNSGSVSPPTSNYRSFSLFSDSNGEPILGKTSSLTSLTNKYENHSLSSPQTAINPVFNNSTTGPILTTLRRNSSSHSQKTLGSIQLQQKPRGSVHKPVRNHSRVSSFDKRMESTATAAATVAAVSGSVQLSQNTTPQNLPHLDNSQNNNYLRDNGMNNIGAGSVGGGLTFGAPSFTQPLSPSDDAIVYPTNQFTNRPATVSTFGGGLDVLVDNSLDPFFNI
What is the function of this protein?
Transcription factor that acts as a negative regulator of fluconazole resistance in C. albicans.  Also confers fluconazole resistance in S. cerevisiae by activation of the PDR5 gene.
What are the official names of this protein?
Fluconazole resistance protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: PRR5_MOUSE
Sequence: MRTLRRLKFMSSPSLSDLGKREPGAAGTDERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFILNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPTLQAIFYPVQGKEPSVRQLALLHFRNTITLSVKLEDALARSHARVPPAIAQMLLVLQGVHESRGVTEDYLRLETLIQKVVSPYLGTYGLYSNEGPCTHSCILEKRFLRRSRSGDILAKNPVVRSKSYNTPLLNPVAEHEAEGTAASGTSIRRHSVSEMTSCPEPQGFVDTPGQGPSGTFRSSPTPHSGPCPSRLYPPAHSPEQGPGHGSPSTSSPETLVDQILESADSDSEGIFIDFGRGSRSSVSDFEAPGGRPSVV
What is the function of this protein?
Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals.  mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive.  mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors.  mTORC2 promotes the serum-induced formation of stress-fibers or F-actin.  mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation.  mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'.  mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'.  PRR5 plays an important role in regulation of PDGFRB expression and in modulation of platelet-derived growth factor signaling.  May act as a tumor suppressor in breast cancer (By similarity).
What are the official names of this protein?
Proline-rich protein 5, Protein observed with Rictor-1, Protor-1.
What is the protein family that this protein belongs to?
Belongs to the PROTOR family.
Protein: PHIPL_BOVIN
Sequence: MEVPRLDHALNSPTSPCEEVIKNLSLEAIQLCDRDGNKSQDSGIAEMEELPVPRNIKISNITCDSFKISWEMDSKSKDRITHYFIDLNKKENKNSNKFKHKDVPTKLVAKAVPLPMTVRGHWFLSPRTEYTVAVQTASKQVDGDYVVSEWSEIIEFCTADYSKVHLTQLLEKAEVIAGRMLKFSVFYRNQHKEYFDYIREHHGNAMQPSVKDNSGSHGSPISGKLEGIFFSCSTEFNTGKPPQDSPYGRYRFEIAAEKLFNPNTNLYFGDFYCMYTAYHYVILVIAPVGSPGDEFCKQRLPQLNSQDNKFLTCREEDGMLVYHHAQDVILEVIYTDPVGLSLGTVAEITGHQLMSLSTANAKKDPSCKTCNISVGR
What is the function of this protein?
May play a role in the development of the central system.
What are the official names of this protein?
Phytanoyl-CoA hydroxylase interacting protein-like.
What is the protein family that this protein belongs to?
Belongs to the PHYHIP family.
Protein: SELA_PSEP1
Sequence: MSNSLASDTPRLPSIDTLLRHPACLPLIDRHGRDAVLNTLRQLLDDLREPARNGELGSAELAPEILLGRSGERLALQQRSQVRRVFNLTGTVLHTNLGRALLPEEAIEAMQTAARYPLNLEFDLATGKRGDRDDLIEGLIRELTGAEAVTVVNNNAAAVLLALNSLGARKEGIISRGELIEIGGAFRIPDIMARAGVKLHEVGTTNRTHARDYEAAIGPRTGLLMRVHCSNYSIQGFTTQVPTAELARIAHQHQLPLLEDLGSGSLLDLTRWGLPAEPTVRQALADGADIVTFSGDKLLGGPQAGIIVGHKDLITRIKKNPLKRALRVDKITLAALEAVLALYRNPDRLAERLPSLRLLTRSQAEIQAQAERLAPELQARLGEQWAIRVEPALGMIGSGSQPVARLPSAALCLRPQVSKKLRGRSLHVLERALRDLPVPVLGRIDDDALWLDLRQLDDEAQWLAQLPALQLGPVQ
What is the function of this protein?
Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
What are the official names of this protein?
L-seryl-tRNA(Sec) selenium transferase, Selenocysteine synthase, Sec synthase, Selenocysteinyl-tRNA(Sec) synthase.
What is the protein family that this protein belongs to?
Belongs to the SelA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNPA_PROM2
Sequence: MALPKDMRLKGHRTFNYIHKNSTIYHGKLMTFKVARSNPEILFTHKLTNNSNKFRMAIAISKKVSKKAVERNKLRRILQEWLLTNIKKINNHKPYWLLVNLKFGDFCNDKSRLLEEFQNLMFKSHLIK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: ARLY_PYRAE
Sequence: MSFYRSWIGGTGDLVKKYTSSIKDDVELAEEVVRVMKGHVAHLVEIGSIPKEAGERIIKALEEVDASELLKEEFEDVHEALEKWLIDKLGEEIGGWVGLGRSRNDHVAAAIRLAALRKTERLKEEACRLRCALAKRALEYADCPMPSFTHFQPAQVITFGHYLLAIDELLAEFLHILRGVEDLLNRSPLGAGPAGGVRTPLDRRRLAELVGFKEVVENALYASGSRFFALALASAVVSFLAELSRAVDDFIRWNSPVVGYVNSPDSHVSTSSIMPHKRNLVTLEVLRARIAEALGHFAAMSALVMKVGMGYSLDLQEATRHLWAVLNIATEGMAVFRDFIENMAFNCEKSRKDAEAYFTTSSDTAEDEALKGVPFRKAYFQLASAIKAGTARLLTINEALKRPVYGSANTEEVKRAASRRLALCRPKPL
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMI_SALTI
Sequence: MTESTFPQYPRLVLSKGREKSLLRRHPWVFSGAVSRLEGKANLGETIDIVDHQGKWLARGAWSPASQIRARVWTFDKTESIDIAFFTRRLRQAQQWRDWLAKKDGLDSYRLIAGESDGLPGVTIDRFGHFLVLQLLSAGAEYQRAALISALQTCYPDCAIYDRSDVAVRKKEGMALTQGPVTGELPPALLPIEEHGMKLLVDIQGGHKTGYYLDQRDSRLVTRRYVENQRVLNCFSYTGGFAVSALMGGCRQVVSVDTSQDALDIARQNVELNQLDLSKAEFVRDDVFKLLRAYREHGEKFDVIIMDPPKFVENKSQLMGACRGYKDINMLAIQLLNPGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
What is the function of this protein?
Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase I, 23S rRNA m5C1962 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RlmI.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RlmI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STHA_ESCF3
Sequence: MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQGFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTHPRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEMSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTDSLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALVKGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMNVGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
What is the function of this protein?
Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation.
What are the official names of this protein?
Soluble pyridine nucleotide transhydrogenase, STH, NAD(P)(+) transhydrogenase [B-specific].
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTLA_LACCA
Sequence: MMATKEEISMVGFALVAYAGDARTAAVHALDAAEAGDFDKANELVEKAQQDINEAHNQQTQLLSQEAGGAEMDVTFIMVHGQDTLMTTMLLIDETRYMIRMFKRIKELENKQ
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II LacEF PTS system is involved in lactose transport.
What are the official names of this protein?
PTS system lactose-specific EIIA component, EIIA-Lac, EIII-Lac, FIII-Lac, Lactose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DXS_NOCFA
Sequence: MGVLSRVDTPEDVRRLNVAELRELAEEIREFLVRKVAATGGHLGPNLGVVELTIALHRVFDSPADPLIFDTGHQAYVHKILTGRKDRFDDLRKQGGLSGYPSRAESPHDWVESSHASAALSYADGLAKAFALGGQDRHVVAVVGDGALTGGMCWEALNNIAAAPDRPVVVVVNDNGRSYAPTIGGLADRLTALRTQPAYEHALDAGKRLLKSIPRVGESAYSMVHAVKAGIKDAVSPQELFSDLGLKYVGPVDGHDVVAMESALRRAKDFGGPVVVHAVTQKGRGYEHAENHVADQMHACDPIDPLTGRPLGGAKARGWTSVFSEELIEHARRRSDIVAITAAMPGPTGLSAFGERFPDRMFDVGIAEQHAMASAAGLALGGMHPVVAIYSTFLNRAFDQLLMDVALLKQPVTVVLDRAGITGPDGASHNGMWDLSLLGIIPGIRVAAPRDAATLREELGEALAVTDGPTVLRFPKGSVAEDLTAVERIDGVDVLRAADPESAVRTQRGDVLIVAVGPFARIGLAAAELLAPEGVSVTVVDPRWVLPVSDTVVKLAENYRLVVTLEDSGLHGGIGSTVSARLRSVGLDVPTRDLGVPQQFLDHASRDQVLEQLGLTPTDVARRIAGWLDAR
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: 034R_IIV6
Sequence: MKQNLLILLSLLLVVVAIMWWLYEKKKEVPLPPPTPPTPPTPTGVPFLPMYAGLSSPVQYNPADYLYGWEKYPHGPAWSFGDRVPYAEAKNALGGHFGGGLYSPRDPILESKLGGVYIGNDLYTVGGVGGDGHW
What are the official names of this protein?
Uncharacterized protein 034R.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: TGT_ECO55
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: TAL_VEREI
Sequence: MNQLDALKQFTTVVADTGDFKQLAQFQPQDATTNPSLILKAVQQPEYAPLLQDTVARCKGRTMDDIIDRLLVRFGCEILAIIPGRVSTEVDARLSFDTYASITRAERIIDLYQAEGIDIDRVLIKIAATWEGIKAAEKLEQRGIHTNLTLLFSFAQAVACGQARVQLISPFVGRIYDWHKKQAGAHWDEAAAAGANDPGVRSVTQIYNHYKHFGIATEVMGASFRNLGQITALAGCDLLTIAPELLARLVASAAPLQPALDAEAAKGMALPAVNYDEAGWRYALNEDAMATEKLAEGIRAFAADAVKLEQLILASG
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.