PharMolix/UniProtQA huggingface dataset:
Protein: PSD12_PONAB
Sequence: MADGGSERADGRIVKMEVDYSPTVDQRLPECAKLAKEGRLQEVIETLLSLEKQTRTASDMVSTSRILVAVVKMCYEAKEWDLLNENIMLLSKRRSQLKQAVAKMVQQCCTYVEEITDLPIKLRLIDTLRMVTEGKIYVEIERARLTKTLATIKEQNGDVKEAASILQELQVETYGSMEKKERVEFILEQMRLCLAVKDYIRTQIISKKINTKFFQEENTEKLKLKYYNLMIQLDQHEGSYLSICKHYRAIYDTPCIQAESEKWQQALKSVVLYVILAPFDNEQSDLVHRISGDKKLEEIPKYKDLLKLFTTMELMRWSTLVEDYGMELRKGSLESPATDVFGSTEEGEKRWKDLKNRVVEHNIRIMAKYYTRITMKRMAQLLDLSVDESEAFLSNLVVNKTIFAKVDRLAGIINFQRPKDPNNLLNDWSQKLNSLMSLVNKTTHLIAKEEMIHNLQ
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
What are the official names of this protein?
26S proteasome non-ATPase regulatory subunit 12, 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit p55.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit p55 family.
Protein: CDC6G_HALMA
Sequence: MATFTRDTEIFRNEDMLREDYQPDSITAREDEISTYMAALQPIVNGAQPRNIFLYGKTGVGKTAVSRYLLKQLQRDTDQYDDVDLSLCWLNCTNLSSSYQVAVNLVNQLRPRDDRISTTGYPQQRVFDILYEELDQIGGTILLVLDEIDHIGSDDEILYEIPQARSNGYLSEAKPGVIGISNDFGFRDNLSPKVKDTLCEEEIHFSPYNAPELRAILEERVTGAMYDDAVDDAVIALCAAIAAQDTGSARQALDILYKSGEIARTNGEERLTEDHVHQAREKLEQSQVEHGMRELTKHGHLALVAMLQLAFEQETPARIRDVYPLYRRIAEGSNVDPLVRRRMHDHLADLAMLGILGRQMKNEGRAGGHYYQYEFDVGLDIVGDVVRDFDSIALPTSVATQIT
What is the function of this protein?
Involved in regulation of DNA replication.
What are the official names of this protein?
ORC1-type DNA replication protein 7.
What is the protein family that this protein belongs to?
Belongs to the CDC6/cdc18 family.
Protein: RL18_THERP
Sequence: MRFQFKRRLSPRKRRHLRVRAKVFGTPERPRLNVFRSNKHIYAQIIDDTRGHTLVAASTLEKEVRERFPDPHPKIEEARIVGQVVGERALAKGITRVVFDRGGYKYHGRVKALADGARAAGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: Y1047_MANSM
Sequence: MLCAIYKSKKKEGMYLYVAKRDYFDEVPETLKMAFGTPNFVMLFNLLGEKKLVRAENQEVLKHIQEQGFYLQMPPKQESLFEQFKAEQKAKQTKNKTALKVR
What are the official names of this protein?
YcgL domain-containing protein MS1047.
Protein: KGX1A_CENMA
Sequence: DRDSCVDKSRCAKYGYFQECTDCCKKYGHNGGTCMFFKCKCA
What is the function of this protein?
Blocks human Kv11. 1/KCNH2/ERG1 potassium channels (reversible, IC(50)=3. 4 nM) (PubMed:34201318).  At high toxin concentrations, block of Kv11. 1/KCNH2/ERG1 macroscopic current is almost complete (PubMed:34201318).  Does not accelerate the kinetics of the closing process and has no effect on the activation and inactivation kinetics of the Kv11. 1/KCNH2/ERG1 channels (PubMed:34201318).
What are the official names of this protein?
Potassium channel toxin gamma-KTx 1.10, CmERG1.
What is the protein family that this protein belongs to?
Belongs to the ergtoxin family. Gamma-KTx 1 subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDD_CHLCH
Sequence: MSIWKIINAIPIVLIRLYRTFLSPLLGPSCKYVPTCSSYALEAFERHNFFYALWLTIWRILRCNPFSKGGYDPVPPLQGTQQSSSHHQESSHHG
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: RASF5_MOUSE
Sequence: MASPAIGQRPYPLLLDPEPPRYLQSLGGTEPPPPARPRRCIPTALIPAAGASEDRGGRRSGRRDPEPTPRDCRHARPVRPGLQPRLRLRPGSHRPRDVRSIFEQPQDPRVLAERGEGHRFVELALRGGPGWCDLCGREVLRQALRCANCKFTCHSECRSLIQLDCRQKGGPALDRRSPESTLTPTLNQNVCKAVEETQHPPTIQEIKQKIDSYNSREKHCLGMKLSEDGTYTGFIKVHLKLRRPVTVPAGIRPQSIYDAIKEVNPAATTDKRTSFYLPLDAIKQLHISSTTTVSEVIQGLLKKFMVVDNPQKFALFKRIHKDGQVLFQKLSIADYPLYLRLLAGPDTDVLSFVLKENETGEVEWDAFSIPELQNFLTILEKEEQDKIHQLQKKYNKFRQKLEEALRESQGKPG
What is the function of this protein?
Potential tumor suppressor.  Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T-cell receptor or chemokine stimulation to integrin activation.  Isoform 2 stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1.  Together with RAP1A may participate in regulation of microtubule growth.  The association of isoform 2 with activated RAP1A is required for directional movement of endothelial cells during wound healing (By similarity).  May be involved in regulation of Ras apoptotic function.  The RASSF5-STK4/MST1 complex may mediate HRAS and KRAS induced apoptosis.
What are the official names of this protein?
Ras association domain-containing protein 5, New ras effector 1, Regulator for cell adhesion and polarization enriched in lymphoid tissues, RAPL.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Note=Isoform 2 is mainly located in the perinuclear region of unstimulated primary T-cells. Upon stimulation translocates to the leading edge and colocalizes with ITGAL/LFA-1 in the peripheral zone of the immunological synapse. Isoform 2 is localized to growing microtubules in vascular endothelial cells and is dissociated from microtubules by activated RAP1A (By similarity).
Protein: PROB_LEPIC
Sequence: MKPERNSLSEKIRNAEKIVIKVGSARLSGLPSEVNDFLFQLVSDIRHLRDLGKKVILVSSGAIARGRLLLSELPSTISSGDSLAEKQALAAMGQNRLVNLYDSFFSKVNLSIAQILFGVLDLESKEGYKNLKNTFTQLVEWGILPVVNENDSVATEEVKFGDNDMLSALVSLIVEADLLIILTGVDGFLKEEKVVPFLEKISKEDLGLAGGPSGPGTGGMFTKLKSAGLLSEAGIPTAILNGKKMHVIREFLEKNSIGTLVAPSGNRVFSEEDVKEIIRKNRNGNGGNSL
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: URE1_PSEP1
Sequence: MSRISRQAYADMFGPTVGDRVRLADTALWVEVEKDFTIYGEEVKFGGGKVIRDGMGQGQMLAAEAMDLVLTNALIIDHWGIVKADIGIKHGRIAVIGKAGNPDVQPGVNVPVGPGTEVIAAEGKIVTAGGVDSHIHFICPQQVDEALNSGVTTFIGGGTGPATGTNATTCTPGPWYLARMLQAADSLPINIGLLGKGNASRPDALREQIGAGAVGLKLHEDWGSTPAAIDCCLGVAEEMDIQVAIHTDTLNESGCIEDTLAAIGDRTIHTFHTEGAGGGHAPDIIRAAGQANVLPSSTNPTLPYTINTVDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDMGAFAMTSSDSQAMGRVGEVVLRTWQVAHQMKLRRGPLAPDTPYSDNFRVKRYIAKYTINPALTHGIGHEVGSVEVGKLADLVLWSPAFFAVKPALVLKGGMIVTAPMGDINGSIPTPQPVHYRSMFGALGAARHATRMTFLPQAAMDRGLAEALNLRSLIGVVNGCRRVRKPDMVHNTLQPLIEVDAQTYQVRADGELLVCEPASELPLAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CX21A_CONPU
Sequence: FELLPSQDRSCCIQKTLECLENYPGQASQRAHYCQQDATTNCPDTYYFGCCPGYATCMSINAGNNVRSAFDKCINRLCFDPGH
What are the official names of this protein?
Conotoxin p21a.
Protein: HEM3_EUGGR
Sequence: MYCGRYETIGETRGNSLNVFIGAAAGFVAAVALINSGLATSFYSTPVRAVPQVIVPSSLAASSQLPVVPKETNIQVNSAQILYPDSTVKGQERTITILGVCSFLSASLFYIWKQFGMKARTTKPADLQEVSGGRIWSLASTTGSNIGAGKTVRVATRKSPLAMWQAEFIQSELERLWPGITVELQPMSTRGDKILDSPLAKVGGKGLFVKELETALLENRSDIAVHSTKDVPMELPEGLVLGVICKRHDPCDAIVFPKGSNLKSLEDLPHGARVGTSSLRRQCQLLLKRPDLKFLELRGNVNTRLAKLDSGDYDAIILAAAGLKRLGFSDRVLPGETNIIDPNVMCPAAGQGALSIELRTNDPEIAALLEPLHHIPDAVTVACERAMNRRLNGGCQVPISGFAQLKDGQLRMEARVGSVTGKGPLIIQSKTFRLPWSGRTWPQLQKESEALGVEVADMLLADGAQAYLDEAYASRTLGWA
What is the function of this protein?
Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
What are the official names of this protein?
Porphobilinogen deaminase, chloroplastic, PBG, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase.
What is the protein family that this protein belongs to?
Belongs to the HMBS family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RL14_STRM5
Sequence: MIQMQSYLDVADNSGAKQVMCFKVLGGSKRRYAGIGDIIKVTVKDAIPRGKVKKGEVYDAVVVRTRKGVRRADGSLIRFDGNAAVLLNSKQEPIGTRIFGPVTRELRSEKFMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: DAPF_SHEB2
Sequence: MIQFTKMHGLGNDFMVVDGVTQNVFFSPEQIRRLADRNFGIGFDQLLLVEPPYDPDLDFHYRIFNADGTEVEQCGNGARCFARFVRNKGLTNKSKIRVSTSSGKMTLRLERDGTVTVNMGVPILEPSQIPFKAKKPEKTYLLQTPMQTFLCGAASMGNPHCVLDVEDVASASVAEIGAMLTKHERFPRGVNVGFMQVVDSGHIKLRVYERGAAETLACGTGACAAVVVGQVQGKLGQQVRVDLPGGTLTINWEGEGKPLWMTGPAQHVYDGQIQL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TGT_VIBCM
Sequence: MKLKFELKKKNGNARRGQLIFERGTVQTPAFMPVGTYGTVKGMTPEEVKETGAQILLGNTFHLWLRPGQEVMKMHGDLHDFMNWQGPILTDSGGFQVFSLGDIRKITEEGVHFRNPVNGDKIFMDAEKSMEIQKDLGSDIVMIFDECTPYPATHDEAKKSMEMSLRWAKRSRDHFDKLENPNNLFGIVQGGVYEDLRDVSVKGLTEIGFDGYAVGGLAVGEPKEDMHRVLEHTCPQLPEDKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTGGVIKIRNAAHKTDTTPLDPHCDCYTCKNYSKSYLHHLDRCNEILGARLNTIHNLRYYQRLMESIRKAIDEDRFDQFVAEFYARRNREVPPLQKDKA
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: MED8_DICDI
Sequence: MNGVDINSNLDSIKAKAEDIRNLLLTTSTGNWEDILGHFVVLSGEYGSLVREVNNIYDSVAVFPEQVTGDPNLIPNLLRTKLSPELETKNRDIINQYVSKNSTHYDPGNQEENIPPLKLHIKSFNDRIDKVDQEFENKIQQISKHKLTKPSASHDTAILKDILSITMLGSGIKINAQQQLAQQQQQQATINALQQQQRLLNAQQQQQQQQQPQALYKLPATNTANTSTNTPSSTIVINSPSPGGIHHNVPTPPTNLNAAGTRTSPPNVQQYVNSPPPQQQQQQQINTVIGTPNTIPTTPTATVSTAATYKPVASPQQQVTSKQVPIQSTNKPLPQQQPSIQIQPQQSIVQMVQNVLPNTTSPPVNNNNQSPINSGIGGGQFKPSAINIANANSGTSTIQQQIQLQQQQLQQQIQLQQQLAQQQQQNQQNQQNQQNQQNQQNQQIHQHIQHLTPQQQAQLQQQMLQQQQLQQQFQQQQLSQQLLQQQQLHQQQQPNQTIQNPFHNFQANNFRVQNPTNFNPPQNQ
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.  May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 8, Putative mediator complex subunit 8.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 8 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPL_BACFR
Sequence: MLLSVLLQAAAAGVGLSKLGAALGAGLAVIGAGIGIGKIGGSAMEGIARQPEASGDIRMNMIIAAALVEGVALLALVVCLLVLFL
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y3086_XANC5
Sequence: MLLPIPDVLSPAQLSQLRAQLDVADWADGRITAGHQSAQAKDNAQLPEDSAVAREAGALVLEALARSSTFFSAVLPRRIYPPLFNRYSGGQSFGYHVDNAIRYDRSRGGADPVRTDVSATLFLSDPDSYDGGELVIEDTYGTQSVKLPAGHLVIYPGTSLHRVMPVTRGARVACFFWTQSMLRDAAQRRLLFELDVSIRRLTQDTPGHPSLIQLTGVYHNLLRQWADV
What are the official names of this protein?
PKHD-type hydroxylase XCV3086.
Protein: Y576_STRP2
Sequence: MNETQIQRETRQVVEDVLEKTNLKQGALFVLGLSSSEVLGGQIGKESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFGLEIVSVHPTLHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHAHVTALTSRPKLIGGARAHYPQDAIRKF
What are the official names of this protein?
UPF0340 protein SPD_0576.
What is the protein family that this protein belongs to?
Belongs to the UPF0340 family.
Protein: THIC_BRASO
Sequence: MNIRSNPDTTLPAVTTGPLPSSRKIYAVPDSAPDLRVPLREIILSEAASEPNLPVYDTSGPYTDPSVTIDVNAGLPRNRIAWVLERGGVEEYVGRDIKPEDNGNVGADKAAKAFTAHHKPLRGLDGHKITQLEFARAGIVTKEMIYVAERENLGRKVQLERAEAALADGESFGASVPAFITPEFVRDEIARGRAIIPCNINHAELEPMIIGRNFLTKINANIGNSAVTSSVEEEVDKMVWAIRWGADTVMDLSTGRNIHTTREWILRNSPVPIGTVPIYQALEKCNGDPVALTWELYKDTLIEQCEQGVDYFTIHAGVRLQYIHLTASRVTGIVSRGGSIMAKWCLAHHKESFLYTHFDEICDIMRKYDVSFSLGDGLRPGSIADANDRAQFAELETLGELTKIAWDKGCQVMIEGPGHVPMHKIKINMDKQLKECGEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGCAMLCYVTPKEHLGLPDRNDVKTGVITYKIAAHAADLAKGHPAAQLRDDALSRARFEFRWTDQFNLGLDPDTAKSFHDETLPKEAHKVAHFCSMCGPKFCSMKITQDVRDYAATLNDPATVGMTISGTIEDGMAQMSAKFKEMGGSVYLDAEKVKESNKALS
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: LEXA_STAAS
Sequence: MRELTKRQSEIYNYIKQVVQTKGYPPSVREIGEAVGLASSSTVHGHLSRLEEKGYIRRDPTKPRAIEIVSDQTNDNINMEETIHVPVIGKVTAGVPITAVENIEEYFPLPEHLTSTHNSDIFILNVVGDSMIEAGILDGDKVIVRSQTIAENGDIIVAMTEEDEATVKRFYKEKNRYRLQPENSTMEPIYLDNVAVIGKVIGLYREM
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: LOLB_SHIF8
Sequence: MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEITYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: Y1092_STAES
Sequence: MVQTVYKNSDQTVFEDAKALFQLNKNILLKGPTGSGKTKLAETLSNVMKLPMHQVNCSVDLDTESLLGFKTIHTNEEGHQEIVFIDGPVIKAMKEGHILYIDEINMAKPETLPILNGVLDYRRQLTNPYTGEVIKAAPGFNVIAAINEGYVGTLPMNEALKNRFIVIEVDYIDGDILKTVIKEQSKLQDEQLIQHIVKFNEDLRTMTKQGQISEEAASIRALIDLSDLATVMPIERAVQRTIIDKLEDEREQQAILNAIELNF
What are the official names of this protein?
Uncharacterized protein SE_1092.
What is the protein family that this protein belongs to?
Belongs to the CbbQ/NirQ/NorQ/GpvN family.
Protein: Y2920_ARATH
Sequence: MLVSLIPELPLENPFQDATDRFYVLPRLIGTVSNMVWPIKILRVAMETTQDLGACDATFYVRYTDSCQARTGEDADRVAIVRRIWDEQFDVFKIVGRTESYRSLGNGESTTSRETVVHCSKDIDSMEQSDMHDGFDGYVGLYSELTNLGSWLVVIHLNMLIRIVNPIAC
What are the official names of this protein?
UPF0725 protein At2g19200.
What is the protein family that this protein belongs to?
Belongs to the UPF0725 (EMB2204) family.
Protein: RR17_EMIHU
Sequence: MVAKEKIGTVVSDKMLNTRIVAVSDRVSHKNYGKVITRTKRYVAHDIESNSKIGDKVKIQETRPISKSKNWILVSILEKSST
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DBPA_BORBU
Sequence: MIKCNNKTFNNLLKLTILVNLLISCGLTGATKIRLERSAKDITDEIDAIKKDAALKGVNFDAFKDKKTGSGVSENPFILEAKVRATTVAEKFVIAIEEEATKLKETGSSGEFSAMYDLMFEVSKPLQKLGIQEMTKTVSDAAEENPPTTAQGVLEIAKKMREKLQRVHTKNYCTLKKKENSTFTDEKCKNN
What is the function of this protein?
Binds to decorin which may mediate the adherence of B. burgdorferi to collagen fibers in skin and other tissues.
What are the official names of this protein?
Decorin-binding protein A.
What is the protein family that this protein belongs to?
Belongs to the decorin-binding protein family.
Protein: GELS_HOMAM
Sequence: MVPAFEGAGAVEGLTIWRIENFEVVPYPKEKYGQFYQGDSYIVLYTRDVNGNLSWDLHFWLGSETSQDEAGTAAIKTVELDDQLGGVPVQHREVEGHETSLFLSRFKKGVRYLKGGVASGFHHVDPDAPYPARLFHVKGRRNIRIRQVEVGVGSMNKGDCFILDCGSQVYAYMGPSSRKMDRLKAIQAANPVRADDHAGKAKVIVIDETASGSEAGESSPGLGGGSPDDVADEDTGVDDSAFERSEVNVVTLHHIFEDGDGVIQTNMIGEKPLLQSMLDSGDCFLLDTGVGVYVWIGSGSSKKEKVKSMELAAGYMEKKGYPTYTNVQRVVEKAEPAVFKAYFKTWREPQEQIGLGRVFTQRQMSAVSATETDFDVSSLHAEKRRLLQKNAGPAFALCPIMVLARRNLGPLRTLKLEPVDESTHGFFFGGDSYVLKYIYEVNGNERYILYFWQGCASSQDEKASSAIHTVRLDNELCGKAVQVRVVQGYEPAHFLRIFKGRMVIFLGGKASGFKNVHDHDTYDVDGTRLFRVRGTCDFDTRAIQQTEVAGSLNSDDVFVLETPGKTYLWIGKGASEEEKAMGEKVVELVSPGRDMVTVAEGEEDDDFWGGLGGKGDYQTARDLDRPLLYPRLFHCTISPAGCLRVNEMSDFAQEDLNEDDVMVLDSGDEVYVWVGQGSDDQEKEKAFTMAENYIKTDPTERTLDATVILRINQGEEPAAFTSIFPAWNPDMWQKGLVSYDDMKAQVPETNAAVE
What is the function of this protein?
Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping).  It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed.
What are the official names of this protein?
Gelsolin, cytoplasmic, Actin-depolymerizing factor, ADF.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DAPA_METS3
Sequence: MNFEGTYVAMVTPFTDDGNIDEEGFRSNINYLIDKGVTGLLGAGTSGESATLTHEEHRKVVEILIDEVGGRVETVAGSGSNSTHEAIELTKSAEELGADAALVITPYYNKPQQHALIKHYQAISDATDIPIIAYNVPSRTGVDMSVETIVELAKIDGVDAVKEASGSVNKVSKLYKALTKEGLEEDFNILSGEDGLTLPIMALGGTGVISASANVDPKRMVLMVDSILNDDYTRAQELHYEMIDVIDALFIESNPVPAKTAMNIMGLPAGPLRAPLTDMKDENVEILKNALKEADLI
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RGAP7_ARATH
Sequence: MEASLAALERPRGSASNTVFKSGPLFISSKGLGWTSWKKRWFILTRTSLVFFKNDPGTLPQKGGEVNLTLGGIDLNNSGSVVVREDKKLLTVLFPDGRDGRAFTLKAETFEDLYEWKTALEQALAQAPNAALIMGQNGIFRAETNEAIEGREKRPLKSLVVGRPILLALEDIDGSPSFLEKALQFIEKYGTKIEGILRQSADVEEVERRVQEYEQGKTEFTFDEDPHVVGDCIKHVLRELPSSPVSASCCTALLEAYRIESKEARISSLRSAIAETFPEPNRRLLQRILKMMHTISSHSHENRMNPNAVAACMAPLLLRPLLAGECDLEDDFDGGEDNSAQLLAAANAANNAQAIITVLLEDYGSIFDEENIQRCSISTESHIGNSGPDDSSDDDNNMKNGYHNADNEVEPVTDDDNDRALSGKMSESSGCTGSDLYEYKGFVADDSDIESPRDTNGPRCNSNIRTDHLMRNPFVNSTDQQAGEQIGDDPTKYGVNSCLAHVSESYQQSGTGLNVPTHGNTLAAPGLESPSAKSVNKGTPSSVHAKRATFWGRGSARKISTDGSFDSSGEDELAIQRLETTKNELRQRIAKEARGNAILQASLERRKQALHERRLSLEQDVSRLQEQLQAERDLRAALEVGLSMSSGQFSSHGVDSKTRAELEEIALAEADVARLKQKVAELHHQLNQQRQTHFGSFSDARDTHQYLQNHNPQKRFLQQDFDSTLAYVNHERKQRHEENVLGAEWRNSKGAGSFGVGNSRQPSRKQIPESTNTTDSKISEESGKISVDKLSSIDSPSIPSTSRVLDITEYPRLNHPSAAASAALVELTTRLDFFKERRSQLMEQLQNLDLNYGGSSSQDFIHRPSSPPWN
What is the function of this protein?
Acts as a GTPase activator for the Rac-type GTPase by converting it to an inactive GDP-bound state.
What are the official names of this protein?
Rho GTPase-activating protein 7, Rho-type GTPase-activating protein 7.
Protein: GET2_CLAL4
Sequence: MSELSAEEKRKLLRERRQAKMAQGKATDRLNNILSQGSSVKSSNVTSVLDKPEKATTTVMDLPSRETQSPTPLHDDPEVPDITSLLKEKENEAPDMEAMLQQILGGSGAHTGPGNDGGANFLQEMMKAMAEDPSGGSTAEESSYQSQLSQYHAYEQKQWKARFLVVRWIIHTLNFVYHYIASGYKLSASPYAFVRAQAVDSHVRTFFTAFLTVEVAVISAYFLVMSQPKFKDFSRENLVSRILSMASAVVPAVGRYQPLVTRALVYWNGASIFVGDLMLMVFYFGITSVLGN
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: XERC_PSEPG
Sequence: MERQLEAYCAHLRNERQVSEHTLLGYRRDLDKVIAYCKEHGIADWQALQIQQLRQLIARLHHHGQSSRSLARLLSAVRGLYRYLNREGLCQHDPATGLSAPKGERRLPKVLDTDRALQLLDGGVDDDFIARRDQAILELFYSSGLRLSELTNLDLDHLDLAAGLVQVLGKGGKARVLPVGRKAREALQAWYRLRGIGNPRDRAVFITRQGNRISPQAVRLRVKAAGERELGQHLHPHMLRHSFASHVLESSQDLRAVQELLGHADISTTQIYTHLDFQHLAAVYDSAHPRAKRSKGNDS
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.