PharMolix/UniProtQA huggingface dataset:
Protein: MEND_ROSS1
Sequence: MTNRNIFYATTLVDELARAGLRFVCLAPGSRNTPLVLACARHPAIKVFSHLDERSAAFFALGLALATDTPAAVVCTSGSAAANFFPAIVEAHQAGVPLLALTADRPHELRDSGANQTIDQVKMFGGFVRWSVDLALPEATPPPVVVRSLRTLAARAMAIAGGEPPGVVHLNLPFRPPLEPTPVAGDITAPPDAAQPRQAGAPYTYCLTATRSGVPEAVIEQIASLLQQHERGLIVCGPRCPSGEFGALVSELADRTGYPALVDGVSGIRFGYPGVIGGYETFLFGEHSFPPPDVVVRFGAVPTSKWLNQYLDTAAPSAVIHVRAGGVWADDSHRVSHFIAADESAFIRALLPHLKERRGAWIQMFEEAEAQVWSAVEAALNDEPYFDGAAVYDAVSLLPEGAALFVGNSLPVRHLDQFGKPGARRIHAFANRGASGIDGNISTALGVGAGRPDTPMAAIVGDITFYHDMNGLLAVRRCGVPITIVLLNNDGGGIFHRLPINRFEPEFTDYFVTPHGLHFAHAAKMYGLDYVQVRDREAFRRAFRESIEARAATIIELRTDARADLARRPALMRSAKASDVRGL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: HISZ_BACAC
Sequence: MTKWKRANPNGTRDYLFEECTLIEEVEQKLRRTFLERGYEEIRTPTIEFYDVFAFQSRPIDEEKMYKFFDEKGRIIVLRPDMTIPLARVVGTQRCDTPLKVTYSGNVFRANESLAGKYNEIVQSGIEVIGIDNVRAEIECVISVIQSLQKLRVQSFTIEIGQVQLYKCIVKKLSIHEEEEKFLRTYIESKNYASLSNFIRDKKLDRCDETVKLLEKLPRLFGNLEVIEEAEKLASSNEMKMAITRVKEIYEAIEKLGYGSYISIDLGTIQHLDYYTGVIFKGYIYEIGEEIVSGGRYDELIGNFGEMLPAVGLAVQVNQIVKALQEQQEPYERKRIDIMIHYELNRLAEAERLRNLLQKDGKKVALSLFSNLNDTFQFARKNQIVTVVEAKSESLVEYVWKEKWVVQKEGETSCVTFKLR
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FLIP_BUCAP
Sequence: MENNVYSQIAPSIFKRIFDDTNIFHVMSSLFGMLLLVLILIWILKKISLLKINKNNYFIKTIDRMSLGPNESIVIIKIEEIKLVLGITKNHITHLYTLSSDVKDDVVDKKKEVILPTKNFNDSLKNFAKIFWKKTMFYRIIPLFFLFLFCPLVYADIPGPTSHILRDGSQTWSLPVQTLIFLTSLTFLPAFLLMMTSFTRIIIVFGLLRNALGTPYAPPNQILLGLALFLTFFIMSPTFDQVYKEAYLPFSQEKINMDEAIIKGAVPLKKFMLNQTRNSDLELFSKLAHISSYKNKDEIPMRILLPSFITSELKTAFQIGFTIFIPFLIIDLVVASVLMALGMMMVPPSTISLPFKLMLFVLVDGWQLLVTSLSQSFKI
What is the function of this protein?
Plays a role in the flagellum-specific transport system.
What are the official names of this protein?
Flagellar biosynthetic protein FliP.
What is the protein family that this protein belongs to?
Belongs to the FliP/MopC/SpaP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Bacterial flagellum basal body.
Protein: Y1149_HALH5
Sequence: MSNVYDKAQELKQALAESEEFKALKSLHTQIDQDDIAKRLLENFRQLQLDLQQKQMQGVQITEEEAQKAQQQFELVQQHELISKLMEEEQRLSVVIGDLNRIITEPLEEIYGNPNE
What are the official names of this protein?
UPF0342 protein BH1149.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: ATPB_CHRVO
Sequence: MSQGKIVQIIGAVIDVEFPRDAMPKVYDALKLVDADLTLEVQQQLGDGVVRTIAMGSSDGLKRGMAVANTGAPISVPVGAATLGRIMDVLGNPVDEAGPVATDARRAIHQAAPKFDELSAAADILETGIKVIDLLCPFAKGGKVGLFGGAGVGKTVNMMELINNIAKAHSGLSVFAGVGERTREGNDFYHEMKDSNVLDKVAMVYGQMNEPPGNRLRVALTGLTMAEHFRDEKDENGKGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGRLQERITSTKDGSITSIQAVYVPADDLTDPSPATTFAHLDATVVLSRDIASLGIYPAVDPLDSTSRQLDPLVVGDEHYTVARGVQSTLQRYKELRDIIAILGMDELSEEDKLVVARARKIQRFLSQPFHVAEVFTGSPGKYVPLRETIKGFKAILAGEYDHLPEQAFYMVGAIEEAAEKAKTLN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: FLVC2_MOUSE
Sequence: MVNESLNQEESNDRPAPESEFQMDTSYSTQPSGSIHPSVSGHPSVSGHPSVSGHPSVSIHPSVSIDPSVSVRPSSSALPSTLAQPSGLTHHSSLVREDSVIKVSKRRWVVVLVFSCYSLCNAFQWIQYGSINNIFMNFYGVSAFAIDWLSMCYMLTYIPLLLPVAWMLEKFGLRTIAITGSALNCLGAWVKLGSLEPHLFPVTMVGQVICSVAQVFILGMPSRIASVWFGADEVSTACSVAVFGNQLGIAIGFLVPPVLVPNIKDPEKLAYHISIMFYIIGGVATFLFILVIIVFKEKPKHPPSRAQSLSYALATTDASYLSSIVRLFKNLNFVLLVITYGLNAGAFYALSTLLNRMVILHFPGEEVNAGRIGLTIVIAGMFGAMISGIWLDKSKTYKETTLVVYIMTLVGMVVYTFTLNLNHLWIVFITAGTLGFFMTGYLPLGFEFAVEFTYPESEGVSSGLLNVSAQVFGIVFTISQGQIIDNHGTMFGNIFLCVFLALGSALTAFIKSDLRRQRANKDAPETKVQEEEEEEEGSNTSKVPVVSEAHL
What is the function of this protein?
Acts as an importer of heme.  Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism (By similarity).
What are the official names of this protein?
Feline leukemia virus subgroup C receptor-related protein 2, Calcium-chelate transporter, CCT.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y1045_ARATH
Sequence: MAQNKNLNLELSLSQYVEDDPWVLKKKLSDSDLYYSAQLYLPKQEMEHFVLPEMDHDLVRKLGAGVEVKVRDVDSVDDFYTVRLKVRNGQYYLGKGWGLIKNAKVLNTGDHIGLFWDKLTREVKFKHFKSQSITMHREAGTTSTQKNVLQKK
What are the official names of this protein?
B3 domain-containing protein At1g10455.
What are the subcellular locations of this protein?
Nucleus.
Protein: PSBN_LILSU
Sequence: METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: CA1E_CONRE
Sequence: GCCSDPRCRYRC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.
What are the official names of this protein?
Alpha-conotoxin-like Reg1e.
What is the protein family that this protein belongs to?
Belongs to the conotoxin A superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: FTSL_MOOTA
Sequence: MLAAPRELSYIPQPVVSSKQSPRSGLSNRRRESRARQKILLLGLVLMGFVIGLSLTFLTMQVLIKGYKIDSLKRELSTLQRENEQLQLEVARLKAPERVARVATTKLGMVEPKTEQIYYVPEQAGNGKQVQVATTEPSRPAVTGAAPGRQAWWVALAEALHQWLEPARQAGAGV
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: VPS71_SCHPO
Sequence: MFVTPIEHAVQKRKKQKQRSVVDPVTRERQLKRNLADLEKDNFSDIRFEIPKDLLQRRVLPISVRRILSSRKTFVNYLDETPNSRYNTCVAKPSYKPPRKFCNVCGYWGKYACQNCGTSYCSKGCEVIHSETRCMKVYA
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A. Z leading to transcriptional regulation of selected genes by chromatin remodeling.
What are the official names of this protein?
SWR1 complex subunit vps71.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: CYSI_ACIF5
Sequence: MSINDKALSDVERIKAESQGLRGTLRESLHNPVTGALAEDDVQVIKFHGIYQQDYRDLRAERHQQKLEPLYQFMARLRLPGGVLSGAQWLALGDIARTYGNASLRITSRQSIQFHGLLKPHLRPVLQALDRALLDTVSACGDVNRNVIASSAPQISAFHAEAYGWAQKIAEHLLPQSHAYHEIWLGGQQITAPEEDLLYGSTYLPRKFKIAIAVPPHNDVDVLTQDLGFIAIHEEGRLAGFNVCVGGGLGRSHNKPDTYSRLADVCGFCAPGQVLAIAEAVLITQRDHGDRSNRSHARLKYTVDRMGLDRFMEEVQQRTGFSLAPPRPFHFETSGDRFGWLENDDGTACLTLFIPGGRVADGDIPLLSGLDALARLHHGEIRLTCNQNLLIAGISPAERPVVETVLAEYGLNRLLNLAPVRAHAMACVALPTCPLAMAEAERYLPVFLDRIEALLAEVGLEGEALTVRMTGCPNGCARPYLAEIGLVGKAPGLYDLYLGGDRTGMRLNALYREALDEEALLDALRPLLKRFAGQRWAGETFGDFVRRQDLLPPDPGLPHTGRR
What is the function of this protein?
Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide.  This is one of several activities required for the biosynthesis of L-cysteine from sulfate.
What are the official names of this protein?
Sulfite reductase [NADPH] hemoprotein beta-component, SiR-HP, SiRHP.
What is the protein family that this protein belongs to?
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Protein: MEND_CORDI
Sequence: MTSSPELARAVAATLARHVTDVVICPGSRNSPLSLELIARDDIRVHTRIDERSAAFLALGLARSSKRHVAVVTTSGTAVANCAPAMIEAAYSHTPLIMVSADRPERLHGTGANQTIEQRGIFNVVDTDHVVDITDLNSISFARNVIHINVALDVPLVDVLPEVGDPVERVREVIEVDHGEVVLNLNERILVVAGDEAWEVPGLEDVPTIAEPSAPAPYHPVHPLAAQIFAHKEIKPEHIVVVGHPTLHRAVLSLLADVPVTVLTKTDTITGNPQAVGSRVKVTGELDKRWLQICEDASTLCADRVKEVLEGHGFTGLHVAAAVADTMAVGDTLFLGASNPVRDASLVGMPLGGVDIFAARGAAGIDGTVSQAVGVALDVQHRDATAIRADRTVALMGDVTFLHDVGGLLGARPENLTIVVANDDGCGIFETLEIGAPEFRPSFEQAFGTPHGVHIEAIAQAYGVNYLRAETLPELIEALIDTTDSAGFNIIEAVTTRSTRRDIDKALTL
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: RPOA_NEIMF
Sequence: MQNSTTEFLKPRQIDVNTFSATRAKVSMQPFERGFGHTLGNALRRILLSSMNGFAPTEVAIAGVLHEYSTVDGIQEDVVDILLNIKGIVFKLHGRSQVQLVLKKSGSGVVSAGDIELPHDVEILNPGHVICHLADNGQIEMEIKVEQGRGYQSVSGRQVVRDENRQIGAIQLDASFSPISRVSFEVEPARVEQRTDLDKLVLDIETDGSIDPEEAVRSAARILIDQMSIFADLQGTPVEEVEEKAPPIDPVLLRPVDDLELTVRSANCLKAEDIYYIGDLIQRTETELLKTPNLGRKSLNEIKEVLASKGLTLGSKLEAWPPVGLEKP
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: RIHA_ECO81
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVASGAVKPLMRNLIIADNVHGESGLDGPALPEPTFAPQNCTAVELMAKTLCESEEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: DNAK_LEPBJ
Sequence: MSKEKIIGIDLGTTNSVVSVMEGGDPVVIQNSEGARTTPSIVAFTAKGENLVGQFAKNQAITNAVNTIRSAKRFIGRRIGECESEMKHVSYKVIRSGNEGVKFETSAGEFTPQEISARVLMKMKQTAEDYLGQKVTKAVITVPAYFNDEQRQATKDAGRIAGLEVERIINEPTAAALAYGFDKKNVNSKIAVYDLGGGTFDISILELADGVFEVKSTNGDTHLGGDDFDMAIMEWMISEFKNQTGIDISADKNTVQRLKEAAEKAKIELSGTMSTQINLPFITADASGPKHLDMTLSRAKFDQLTKSLVDRTRIPCENALRDAGLKASDINEVILVGGSIRIPAVQELVKQIFGKEPNKSVNPDEVVAVGAAIQGGVLAGEVSDVLLLDVTPLSLGIETLGGVMTKLIERNTTIPTKKSQVFSTAADNQSAVSIHVLQGEREMASANRTLGRFDLIGIPPAPRGVPQIEVTFDIDANGIVHVSAKDLGTGKEQKIRIESSSGLSEDEIQKMVKDAEAHAAADKAQREVIEAKNELDTLAYSLEKTVNEAGDKIGASEKQLATDEVKRAREAIESNDKARMESAKASISKIASDIATKVYSQGAPGAEQAAGSTGPDQGQNDQGNSGNNGEKVVDADYTVVDDEKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: CH10_ANAPZ
Sequence: MNLAMLHDNVLVEALEDSNPNSPIQLPDSAKKKPTKGKVVSVGPGASNSDGKVTPMSVKVGDCVYYRQWAGNEIEFDGKKFIVMKESDIIAKEA
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOZ_PECAS
Sequence: MARVTVQDAVEKIGNRFDLVLVAARRARQLQTGGKDPLVPEENDKYTVIALREIEDGLINNQILDVRDRQEQQEQEAAEIQAVTAIAEGRR
What is the function of this protein?
Promotes RNA polymerase assembly.  Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
What are the official names of this protein?
DNA-directed RNA polymerase subunit omega, RNAP omega subunit, RNA polymerase omega subunit, Transcriptase subunit omega.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase subunit omega family.
Protein: GDF6_MOUSE
Sequence: MDTPRVLLWAIFLISFLWDLPGFQQASISSSSSSSTELDSTKDVGNRKEGKMQRTPQESAEGRTPPEHGLRQKDLRRRPPGQHQGQEPPGRGLRVVPHEYMLSIYKTYSIAEKLGINASFFQSSKSANTITSFVDRGLDDLSHTPLRRQKYLFDVSTLSDKEELVGAELRLYRQAPPTPWGLPARPLHLQLFPCLSPLLLDARTLDPQGPTQAGWEVFDVWQGLRPQPWKQLCLELRAAWGELDAGDTGARARGPQQPPPLDLRSLGFGRRVRPPQERALLVVFTRSQRKNLFTEMHEQLGSAEAAGAEGSWPAPSGSPDAGSWLPSPGRRRRRTAFASRHGKRHGKKSRLRCSRKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSMDPGSTPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGCR
What is the function of this protein?
Growth factor that controls proliferation and cellular differentiation in the retina and bone formation.  Plays a key role in regulating apoptosis during retinal development.  Establishes dorsal-ventral positional information in the retina and controls the formation of the retinotectal map (PubMed:23307924).  Required for normal formation of bones and joints in the limbs, skull, digits and axial skeleton.  Plays a key role in establishing boundaries between skeletal elements during development.  Regulation of GDF6 expression seems to be a mechanism for evolving species-specific changes in skeletal structures (PubMed:26774823).  Seems to positively regulate differentiation of chondrogenic tissue through the growth factor receptors subunits BMPR1A, BMPR1B, BMPR2 and ACVR2A, leading to the activation of SMAD1-SMAD5-SMAD8 complex.  The regulation of chondrogenic differentiation is inhibited by NOG (PubMed:12606286, PubMed:16049014).  Also involved in the induction of adipogenesis from mesenchymal stem cells.  This mechanism acts through the growth factor receptors subunits BMPR1A, BMPR2 and ACVR2A and the activation of SMAD1-SMAD5-SMAD8 complex and MAPK14/p38 (PubMed:23527555).
What are the official names of this protein?
Growth/differentiation factor 6, GDF-6, Bone morphogenetic protein 13, BMP-13, Growth/differentiation factor 16.
What is the protein family that this protein belongs to?
Belongs to the TGF-beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: FPG_DESHD
Sequence: MPELPEVETIRRSLSQHILERRIEEILIRWPGAVEGYEEKTFADAVRGLKFQSIERRGKYLLFTLEEGWSFIAHMRMTGRMVYHAQSQEPEKHTHVVLKLSSGEIHFTDTRKFGRLQLVRTEERLQQPSLARLGPEPLEEGFSAAELGRRLAPRKLAIKAALLDQTLVAGIGNIYADEALFRAGIAPERCANSLTKEEIEKLYPAICQVLEEGIAANGTSFRDYQDANGERGDFQKELKVYGRGGEPCKECGHTLVRIRLAGRSTVFCPCCQV
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PUR6_CHICK
Sequence: MAPAASELKLGKKVNEGKTKEVYELPDIPGCVLMQSKDQITAGNAARKDRMEGKAAISNTTTSCVFQLLQEAGIKTAFVRKQSDTAFIAAHCEMIPIEWVCRRIATGSFLKRNPGVKEGYKFYPPKIEMFYKDDANNDPQWSEEQLIEAKFSFAGLTIGKTEVDIMARSTQAIFEILEKSWQPQNCTLVDLKIEFGVNILTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEALQMVKRNFEWVAERVELLLKTKSQGRVVVLMGSTSDLGHCEKIKKACATFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVVNCPPLSSDWGAQDVWSSLRLPSGLGCPTTLSPEGAAQFAAQIFGLNNHLVWAKLRSNMLNTWISLKQADKKLRECTL
What are the official names of this protein?
Multifunctional protein ADE2.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily.
Protein: RELE2_CAUVC
Sequence: MAQVVWTWRALADLTAIRDYIGQFSPLAAQRMALRLKTAADSLAEYPERGRLATATLRELVVVPPYVIRYYVADGLVHIVRIRHAARL
What is the function of this protein?
Toxic component of a type II toxin-antitoxin (TA) system.  Its toxic effect is neutralized by coexpression with cognate antitoxin RelB2 but no other ParD or RelB antitoxin.
What are the official names of this protein?
Toxin RelE2.
What is the protein family that this protein belongs to?
Belongs to the RelE toxin family.
Protein: RS12_ACIET
Sequence: MPTINQLVRQGRTVEVVKSKSPAMENCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGSLDLQGVKDRKQARSKYGAKKPKAK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: RUTB_METEP
Sequence: MDADAPAGYRDPSGRHGAVTLPARPEPVAFDADATVLIVVDMQNAYATKGGYLDLAGFDVSATGPVIERIARAVAAARAAGIRVVWFQNGWDPDYVEAGGPGSPNWHKSNALKTMRRRPEMNQRLLAKGTWDYALVDALTPEPGDIVLPKPRYSGFYNTPLDSMLRARGIRTLVFTGIATNVCVESTLRDGYHREYFGIVLADATHQAGPPALQEGALRNIETFFGWVSDVAAFEAALSSDEARRIPA
What is the function of this protein?
Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate.  The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2.
What are the official names of this protein?
Ureidoacrylate amidohydrolase RutB.
What is the protein family that this protein belongs to?
Belongs to the isochorismatase family. RutB subfamily.
Protein: RL10_ENTCL
Sequence: MALNLQDKQAIVAEVSEVAKGALS
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: CCME_METNO
Sequence: MTRKQRRLMLIGVCGAVLAVALGLVLWAMRGTIVFFRSPSEIASQAVAPGVRFRLGGLVQEGSVQRGPDGRVAFVVTDNGATVPVRYQGLLPDLFREGQGVVAEGMLEPGGMFRADTVLAKHDETYMPREVADALKKQGHWQGEAKHPGGTAPAPQTASGEKPALRQQ
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE, Cytochrome c maturation protein E, Heme chaperone CcmE.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: DPOL_ADE12
Sequence: MLFSLTDTMDSSRLYALISRFRPSRAEIWTCRSRGTVTLSVLAFEDPNGSGNAAEEEEDERQLPSGIDFPICFLVRGRQVHLIQQIQPVQRCEHCARFYKHQHECSVRRRDFYFHHINSHSSNWWQEIHFFPIGSHPRTERLFITYDVETYTWMGAFGKQLVPFMLVMKLSGDDNLVKHALQLALELGWDQWEKDSTTFYCLTPEKMKVGQQFRTYRNRLQTSLATDLWMTFLQKNPHLSQWAQEENGLVALEDLSYEDLKRAPAIKGEPRFVELYIVGHNINGFDEIVLAAQVINNRLDVPGPFKISRNFIPRAGKILFNDITFALPNPHYKKRTNFLLWEHGGCDDQDFKYQYLKVMVRDTFALTHTSLRKAAQAYALPVEKGCCPYKAVNQFYMLGSYRADANGFPLEEYWKDKEEYLLNQELWKKKGEKNYNLIGETLNYCALDVLVTASLVEKLRSSYAQFVTDAVGLDAAHFNVFQRPTISSNSHAIFRQILYRAEKPQRTHLGPNILAPSHELYDYVRASIRGGRCYPTYIGVLKEPIYVYDICGMYASALTHPMPWGPPLNPYERALAVRQWQVALENYTCKIDYFDKNLCPGIFTIDADPPDENQLDVLPPFCSRKGGRLAWTNESLRGEVVTSVDLVTLHNRGWRLRLLSDERTTIFPTWKCLAREYVQLNIAAKERADRDKNQTLRSIAKLLSNALYGSFATKLDNKKIVFSDQMEESLMKEIAAGRLNIKSSSFIETDTLSTEVMPAFERVYSPNQLALVNSEAEESDEDQGPAPFYSPPPENCEHVTYTYKPITFMDAEEGDMCLHTLESSNPLINNDRYPSHVASFVLAWTRAFVSEWSEFLYEEDRGIPLKDRPLKSVYGDTDSLFVTEKGRRLMESQGKKRIKKYGGKLVFDPSCPELTWSVECETVCSYCGADAYSPESVFLAPKLYALKCLQCPHCGSTSKGKIRAKGHATEALSYDLMLKCYLAEAQGEDTRFSTSRLSLKRTLASAQPGAHPFTVTETTLTRTLRPWKDKTLVHLDAHRLVPYSNSQPNPRNEEVCWIEMA
What is the function of this protein?
Eukaryotic-type DNA polymerase involved in viral genomic replication.  DNA synthesis is protein primed, and acts in a strand displacement replication.  Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication.  The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: MURA_METI4
Sequence: MEKFIIKGGNPLEGKITISGSKNSALPILAATLLTPEECVIHRVPNLSDIRYMLEILKFLGAQVHYEKGTVRIKSKIVHSTAPYDLVRKMRASICILGPLIARCGQARVSLPGGCVIGDRPIDLHITGLQKLGADIEIIKGDVVAHGGILRGTSINLKGKYGSTVLGTDNVMMAACQAEGTTIIEGAACEPEVEDLAHFLSSMGAKISGMGTQQLIIEGVKELHGCEYTIITDRIEAGTFAVAAAMTKGNLLLEHAPVEHMGSVLEKLKDCGASIEIESQGIRVSRSGPLRAFEIVTAAYPGFPTDMQAQFCAMATVAEGTSKIVENIFPNRFMHISELKRLGAMIELSQNQALIHGTERLSGAPVMASDLRASAALVLAGLVAENTTEVHRVYHIDRGYEKIDEKLSSVGANITRVYSKI
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KRUP_TRICA
Sequence: ERTHTGEKPFECQECHKRFTRDHHLKTHMRLHTGERPYRCEHCDRQFVQVANLRRHLRVHTGERPYGCEHCSMK
What is the function of this protein?
Krueppel is a gap class segmentation protein.
What are the official names of this protein?
Protein krueppel.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.