PharMolix/UniProtQA huggingface dataset:
Protein: DUT_METSB
Sequence: MSEPLTIGIKRLPHGADLPLPAYQSAGAAGLDLLAAIAPGSKLTLEPGERRLVPTGLVLQIPPSHEGQLRPRSGLALKAGVTVLNAPGTIDSDYRGEVGVLLINFGAEPFEIARGERIAQLIIAPVTRAVLVETDGLEATARGAGGFGSTGAAAIGETRR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: GNRR2_CHLAE
Sequence: MSAGNGTPWGSAVGEEAWAGSGVAVEGSELPTFSTAAKVRVGVTIVLFVSSAGGNLAVLWSVTRPQPSQLRPSPVRTLFAHLAAADLLVTFVVMPLDATWNITVQWLAGDIACRTLMFLKLMAMYSAAFLPVVIGLDRQAAVLNPLGSRSGVRKLLGAAWGLSFLLALPQLFLFHTVHRAGPVPFTQCVTKGSFKARWQETTYNLFTFCCLFLLPLIAMAICYSRIVLSVSSPQTRKGSHAPAGEFALRRSFDNRPRVCLRALRLALLILLTFILCWTPYYLLGLWYWFSPTMLTEVPPSLSHILFLFGLLNAPLDPLLYGAFTFGCRRGHQELSIDSSKEGSGRMLQQEIHALRQQEVQKTVTSRSAGETKGISITSI
What is the function of this protein?
Receptor for gonadotropin releasing hormone II (GnRH II).  This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
What are the official names of this protein?
Gonadotropin-releasing hormone II receptor, GnRH II receptor, GnRH-II-R, Type II GnRH receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS11_XANP2
Sequence: MAKEATRVKRRERKNIASGVAHVNASFNNTMITITDAQGNTISWSSAGAMGFKGSRKSTPYAAQVAAEDAARKAAEHGMRTLEVEVSGPGSGRESALRALQAAGFLVTSIRDVTPIPHNGCRPRKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RIMO_NITEC
Sequence: MTAASSLHPPAIPRVGFVSLGCPKATVDSERILTCLRAEGYLISPNYADADLVVVNTCGFIDSAVAESLETIGEALTENGKVIVTGCLGAKEDVIRQAHPSVLAVTGPQATEEVMAAIHHHLPKPHDPYLDLVPPQGIKLTPKHYAYLKISEGCNHHCTFCIIPSMRGDLVSRPVGGVLQEAQSLVEAGVKELLIISQDTSAYGVDIKYRTGFWQGRPVRTRITELANALGEFGIWVRLHYVYPYPHVDELIPLMAEGKLLPYLDIPFQHANKRILKLMKRPANSENVLVRIQQWRKTCPDIALRSTFIVGFPGETEAEFEELLAFLEEAQLDRVGAFTYSPVKGAAANVLPDHVPPEIQQERLERLMQQQEIISKQRLAVKKGQQLRVLVDTVDEEGAIARSYADAPEIDGVVYINDASTLKPGDWADVRVTDTDIHDLWTEKI
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_NOCFA
Sequence: MTVAVRVIPCLDVDAGRVVKGVNFQNLRDAGDPVELAATYDAQGADELTFLDVTASTGDRGTMIDVVTRTAEQIFIPLTVGGGVRTVEDVDRLLRAGADKVSVNTAAIARPEVLREMSERFGSQCIVLSVDARTVPDGQPDTPSGWEVTTHGGKRGTGIDAVEWAERGAELGVGEILLNSMDADGTKTGFDLPMIRAVRAAVSIPVIASGGAGAVEHFAPAVQAGADAVLAASVFHFGDLTIGQVKDSLRDAHLVVR
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OFOB1_SULTO
Sequence: MAAFKPQWNDWCPGCGNFGILNAEQQAIVELGVDTKNVVVVSGIGCSGKIPHFFRTPISGVHTLHGRAIAFATGIKLSNPDLVVIVNGGDGDLLGIGAGHFVAAGRRNVDMVVILHDNGVYGLTKGQASPTLKRGEKPKSLPRPNINDAVNPIALAISSGYTFVARGYAYDVKHLKELIKSAIKHKGLALIDVLQPCPTYNDINTKEWYDKRIYKLDTLPDWDPVVKKPEEVNEKIKRAIDKSLEWGDRIPIGIFYQNELVPSYEERIKANSPAYLDYTPAKQLIEKEGKLTTIIDPLLKEREVD
What is the function of this protein?
Catalyzes the coenzyme A-dependent oxidative decarboxylation of different 2-oxoacids such as 2-oxoglutarate, pyruvate and 2-oxobutyrate to form their CoA derivatives.
What are the official names of this protein?
2-oxoacid:ferredoxin oxidoreductase 1, subunit beta, OFOR1.
Protein: YQGF_ACIAD
Sequence: MPDSMSHQMIMAFDFGTQKMGIAIGQAAIESSTPLALFPMKDGIPDWNQLLKIVKEWQPTLFLVGLPLNMDDSESELSARARKFARRLRHQTNITTWMVDERLTTREARDELESYQEQGRAKKIAADSIAASLLIQSWYRAPQGVQP
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HSF_XENLA
Sequence: MDPHGTCGGSNVPAFLAKLWTLVEDPDTDPLICWSPEGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPYFIRGQEQLLENIKRKVNTMSATKSDEVKVRQDSVGKLISDVQSMKGKQESIDGRLLSMKHENEALWREVASLRQKHTQQQKVVNKLIQFLVSLVQSNRILGVKRKIPLMLNDSSTGHSPPKYSRQYSLEHVPSSTSYPVSGFTDSSAGPIISDVTELPESSPSPSPCPSLEASPSPVILIKTEPLTPSQSPEQSPAPPKLDDTPISPSTFIDSILLETETSVCPGGNKNDEMSESHPPEPCLSVACLDNISLSRQMSEVSRLFPTSCSSVPGRAEPPGLDMAVAELNDHVDNIDFNLDTLQNLLNGQSFSVDTSALMDLFSPSLGIPDLSLPDPDSSLASVSSTPIYTCVV
What is the function of this protein?
DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription.
What are the official names of this protein?
Heat shock factor protein, HSF, Heat shock transcription factor, HSTF.
What is the protein family that this protein belongs to?
Belongs to the HSF family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SYI_DESHD
Sequence: MDYRNTLNLPETDFPMRGNLPQREPEILQKWEEEDIYATVQKARAGRPKFVLHDGPPYANGDIHLGHALNKVIKDIIVKYKTMAGFDAPYVPGWDTHGLPIEQQVIKKLGVNRHAVSVVEFRRMCKEYAKKYISIQKEQFKRLGVRGDWQNPYLTLEKEYEAAQIGVFGKMARKKYIYKGLKPVYWCPSCETALAEAEIEYAEKTSHAIYVKFPVKEGKGVLTDENTFVIIWTTTPWTLPANLAITLHEEFSYVQVQVEKEHWLVAEGMLESLRSLWNLELPVEKRFVGKELEGVICKHPFIERDSVLILGEHVTLEAGTGCVHTAPGHGEEDFNVGKKYGLPVLCPVDHQGKFTAEGGAYAGMKVDKANPVIIEDLKNLHALVHEDKIKHSYAHCWRCNNPIIYRATEQWFASIDGFRKAALEEIDKVQWIPSWGKDRIYNMIADRGDWCISRQRTWGVPIPIFYCEDCGKEIISDETIAKVQEIFREEGSDAWFLRPAAELLPEGFTCACGGKSFRKETDIMDVWFDSGTSHTSVLMERKELAWPADLYMEGSDQHRGWFNSSLSTSVAAYGKAPYKAVLTHGFLVDEKGRKMSKSLGNGVDPLQVTKEMGADILRLWVCAADYKNDVAVSPRIMKQMSEAYRKIRNTLRFLLSNLNDFDPAKDRVAYKDLPEIDRWALLQLGKVTQRVLQGYEKYEFHWVYHSVHNFCAVELSAIYLDIVKDRLYVEGKNSTLRRASQTVLYDVLNALVRLMAPVLTYTADEIWPYVPGVPAGSHVQTEEMPEALPQWLDEALEKKWDTLLAVRSEVTKALEKARQDKLINHPLTAQVDLYPNAELEGFLRGIPNLSEIFIVSAVQLHSAGEEKPEGLSMAEDLAGFGIAVNSAAGEKCERCWIYDTGVGENQEHPTLCPRCASVVSHL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSID_ECOL6
Sequence: MRLFNWRRQAALNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAALFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVLGSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGTVSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPALAIFLTVLAFNLLGDGLRDALDPKIKG
What is the function of this protein?
Part of the ABC transporter complex GsiABCD involved in glutathione import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Glutathione transport system permease protein GsiD.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CYML5_MELLF
Sequence: GSAIACGESCFKFKCYTPGCSCSYPICKKD
What is the function of this protein?
Probably participates in a plant defense mechanism (Potential).  Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) (By similarity).
What are the official names of this protein?
Cyclotide mela-5.
What is the protein family that this protein belongs to?
Belongs to the cyclotide family. Moebuis subfamily.
Protein: KDPA_SALA4
Sequence: MAAQGFLLIASFLLILLVLAKPLGSGLARLIAAVPLPGVAGVERILWRTLGITDHEMNWRQYLLALLTLNLLGLGILFCLLFWQEWLPLNPQRLPGLSWDLALNTAVSFVTNTNWQAYSGESTLSYFSQMAGLTVQNFLSAATGIAVVFALIRAFTRQNVHTLGNAWQDLVRITLWILFPVALIIALFFIQQGVPQNLSAYQPITTLEGAKQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNLAQMLAIFLIPAALCFAFGEAAGDRRQGRALLWAMSFIFVVCVAVVMWAEVQGNPHLLAAGADSSVNMEGKETRFGVLASSLFAVVTTAASCGAVNAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMLLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKMTALAILVTPMLVLLGSALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKVQPASQGTLATHGALFIGLLIGTVLLVGALTFIPALALGPVAEHFSLP
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
What are the official names of this protein?
Potassium-transporting ATPase potassium-binding subunit, ATP phosphohydrolase [potassium-transporting] A chain, Potassium-binding and translocating subunit A, Potassium-translocating ATPase A chain.
What is the protein family that this protein belongs to?
Belongs to the KdpA family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPF_RICCN
Sequence: MISKINFVKMHGLGNDFVIVNKRDLSSSYDLSQLAKNMAERHTGIGCDQFIIYEEHNDFYEMIIYNIDGSSAKLCGNATRCLAKLIYLDTGKQDITVMVGNKKLLCNVNDENNISVNVGSVSFNEAWMPSRDKVWEFAERYMIDLKETICVDIGNPHVVIFSKLEPQDQKIVGERLQAKELFADGVNVNFAEVKDNKIYLSVWERGAGLTLACGSGACGSFAAGLKRGFIHSPSTIVFKHGNLTMKEENGNIIMQGAATLVARGEYYCEQ
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GHRA_KLEP3
Sequence: MEIIFYHQTFDTPFWIRELEKQLPGARVREWKAGDNQPADYALVWHPPVEMLQGRALKAVFALGAGVDSILSKLRDHPDMLPLSIPLFRLEDTGMGRQMQEYAVSQVLHWFRRFDDYQALKLASRWQPLPEYRADEFTVGIMGAGVLGAKVAESLQPWGFPLRVWSRSRKSWPQVQSFAGQAELGEFLQGTRVLINLLPNTAETAGIINQTLLAQLPDESYVLNLARGVHVVEEDLLAALNSGKLKGAMLDVFSREPLPQESPLWAHPRVAMTPHVAAVTRPMEAITYIAETISRLERGEPVSGQVDRQRGY
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively.
What are the official names of this protein?
Glyoxylate/hydroxypyruvate reductase A, 2-ketoacid reductase.
What is the protein family that this protein belongs to?
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_PECAS
Sequence: MAKQSMKAREVVRVKLAEKYRAKREELKAIISGVNSSDEDRWDAVLKLQTLPRDSSPSRQRNRCRQTGRPHAFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RL26A_YEAST
Sequence: MAKQSLDVSSDRRKARKAYFTAPSSQRRVLLSAPLSKELRAQYGIKALPIRRDDEVLVVRGSKKGQEGKISSVYRLKFAVQVDKVTKEKVNGASVPINLHPSKLVITKLHLDKDRKALIQRKGGKLE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L26-A, L33, Large ribosomal subunit protein uL24-A, YL33.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: SETD7_MOUSE
Sequence: MDSDDEVVEEAVEGHLDDDGLPHGFCTVTYSSTDRFEGNFVHGEKNGRGKFFFFDGSTLEGYYVDDALQGQGVYTYEDGGVLQGTYVDGELNGPAQEYDSDGRLIFKGQYKDNNRHGVCWIHYPDGGSLVGEVNEDGEMTGEKIAYVYPDQRTALYGKFIDGEMLEGKLATLMATEEGRPHFEVTSGSSVYHFDKSTSSCISSDALLPDPYESERVYVADSLISSAGEGLFSKVAVGPNTVMSFYNGVRITHQEVDSRDWALNGNTLSLDEETVIDVPEPYNHVSKYCASLGHKANHSFTPNCVYDLFVHPRFGPIKCIRTLRAVEAEEELTVAYGYDHSPPGKSGPEAPEWYQVELKAFQATQQK
What is the function of this protein?
Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3 (By similarity).  H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation (By similarity).  Plays a central role in the transcriptional activation of genes such as collagenase or insulin (PubMed:12711597).  Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription (By similarity).  Has also methyltransferase activity toward non-histone proteins such as CGAS, p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins (PubMed:35210392).  Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II (By similarity).  Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation (By similarity).  Monomethylates 'Lys-491' of CGAS, promoting interaction between SGF29 and CGAS (PubMed:35210392).
What are the official names of this protein?
Histone-lysine N-methyltransferase SETD7, Histone H3-K4 methyltransferase SETD7, H3-K4-HMTase SETD7, SET domain-containing protein 7, SET7/9.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET7 subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: DAPE_RHIME
Sequence: MFPTDPVSNLAALIRCPSVTPAEGGALAALEAMLAPVGFKVDRVVAKEPGTPDIENLYARTGGEGPHLMFAGHTDVVPVGDEAAWSRPPFSAAIAEGEMYGRGAVDMKGGIACFVAAVARHIEKHGAPKGSISFLITGDEEGPAINGTVKLLEWAAARGERWDACLVGEPTNPDCIGDMIKIGRRGSLSGRITVHGVQGHAAYPHLADNPVRSILQIAQALMDPPFDDGTENFQPSNLEVTTIDVGNTAVNVIPAKASAAFNIRFNDRWTAESLMAEIVARLDRAAAGSALRPGRAPARYEIVWNERPSHVFLTRNNALIDSLSGAVEAVTGRQPQLSTTGGTSDARFIKDYCPVVEFGLVGKTMHMVDERVALADLETLTGIYETFIARWFGHAAA
What is the function of this protein?
Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
What are the official names of this protein?
Succinyl-diaminopimelate desuccinylase, SDAP desuccinylase, N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. DapE subfamily.
Protein: YBEY_WOLSU
Sequence: MIDFDNQTDTNLDITLLESIATFLSPREVELILLDDEAMRKINQEHRGIDKSTDVLSFPLEGGDFLPLGSILLSIDRVRAEAELRGHSIEAEAALLFIHGMLHLLGYDHEYDQGEQRFKEEELITRFGLPSSLIVRTEEL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDB23_PANIM
Sequence: GKVWDWIKSAAKKIWSSEPVSQLKGQVLNAAKNYVAEKIGATPT
What is the function of this protein?
Disrupts cell membranes through formation of pores.  Strong antimicrobial activity against Gram-positive bacteria B. subtilis, S. epidermidis, E. faecalis and S. aureus.  Less active against Gram-negative bacteria P. aeruginosa and E. coli.  Has no antifungal or hemolytic activity.
What are the official names of this protein?
Pandinin-1, Pin1, Non-disulfide-bridged peptide 2.3, NDBP-2.3, Non-disulfide-bridged peptide 3.4, NDBP-3.4.
What is the protein family that this protein belongs to?
Belongs to the non-disulfide-bridged peptide (NDBP) superfamily. Long chain multifunctional peptide (group 2) family.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the prey.
Protein: ATP8_BOSMU
Sequence: MPQLDTSTWLTMILSMFLTLFIIFQLKISKHNFYYNPELTSTKMLKQNTPWETKWTKIYLPLLLPL
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  Part of the complex F(0) domain.  Minor subunit located with subunit a in the membrane (By similarity).
What are the official names of this protein?
ATP synthase protein 8, A6L, F-ATPase subunit 8.
What is the protein family that this protein belongs to?
Belongs to the ATPase protein 8 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: SDF2B_DROPE
Sequence: MLRQFLFSTASRRLVRPMIAPHRSASSSLDKTEFTTPSQIVDYDDPPHLPVPEYPLRPDEPLETRKQRLLYQSRKRGMLENDLLLSTFVAKHLRDFSAAQTAQYDDLINGVSNDWDIFYWATETKPTPPQYDTEIMRMLKQHVKNEERVQRIRQPDL
What is the function of this protein?
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
What are the official names of this protein?
Succinate dehydrogenase assembly factor 2-B, mitochondrial, SDH assembly factor 2-B, SDHAF2-B.
What is the protein family that this protein belongs to?
Belongs to the SDHAF2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PER3_BETPN
Sequence: NLAPLDLQTPTAFDNNYYK
What is the function of this protein?
Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress.  These functions might be dependent on each isozyme/isoform in each plant tissue.
What are the official names of this protein?
Peroxidase 3.
What is the protein family that this protein belongs to?
Belongs to the peroxidase family. Classical plant (class III) peroxidase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GUAA_BACAA
Sequence: MIILKKQHDTIIVLDFGSQYNQLIARRIREFGVYSELHPHTITAEEIKAMNPKGIIFSGGPNSVYGEGALHCDEKIFDLGLPIFGICYGMQLMTQQFGGTVERANHREYGKAVLKVENESKLYANLPEEQVVWMSHGDLVTGLPEGFVVDATSESCPIAGMSNEAKNLYGVQFHPEVRHSEHGNDLIKNFVFGVCGCSEGWNMENFIEVELEKIRETVGDKKVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFHMNVIKVDAKERFMNKLKGVEDPEQKRKIIGNEFIYVFDDEASKLEGMDFLAQGTLYTDIVESGTATAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRVLGSELGIPDEIVWRQPFPGPGLGIRVLGEITEEKLEIVRESDAILREEIIKAGLDREIWQYFTALPGMRSVGVMGDERTYDYTVGIRAVTSIDGMTADWARIPWDVLEKISVRIVNEVKHVNRIVYDVTSKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: FSQD_ASPFU
Sequence: MLRASASGAKCAVKLIVPLHRGFIVRSDIIPLRLRDSEYVESAVSFAEPLQTYSGKKVAISSRSDLTTYFAAAAAGLILRQGSTHASDAGSQALFQMVESDLANRLSFPWIQPGTPRRRTLALVDANSSHPQDGLGFYRAARELGINVVVLENAGHWLEDPAQAHWREAFIPTRLTNPPEEDVGDHILASLRAYGKPVDGIVTFADSFWYYIARIAHEIGVETAPPDSMRIATNKFLTSKYVGHDAYLASNVDEALRIAKEVALPYPLIVKPCDGWSSEGVSRVESPDAFPAAVKSIDTSRHGTEFVMEPYCDGPEVDVNLVLLDGEVLFAEICDDLPKSADVNGLTVGSLTNFHELYSVYPSALPSKELELLIHSFVDTLLRLGIRNGVMHLEGRVQNSSMEYREQNRMMHLQPRAPQATRPEPSAWLIEINPRPLGMTGSHIIESTYGIDYWGLAAVLGVGDKDRARALSQPYRDGPQYTCVMVFIPADFPPSSQGIFDTDDICADLLARRPDLAQHISRCATLVRRGQKVAHPTTGRHTFLAYFNVFSRAGREEALDLARQVREEVRYSFL
What is the function of this protein?
ATP-grasp enzyme; part of the gene cluster that mediates the biosynthesis of the isoquinoline alkaloids fumisoquin A, fumisoquin B and fumisoquin C; as well as small amounts of fumipyrrole as a shunt metabolite (PubMed:25582336, PubMed:27065235).  The products of the cluster lead to a brown coloration and are important for growth and conidiation (PubMed:25582336).  The nonribosomal peptide synthetase-like protein fsqF, which lacks a canonical condensation domain, is required for addition of a serine-derived dehydroalanine moiety to activated tyrosine but is not essential for the subsequent steps leading to isoquinoline formation (PubMed:27065235).  A different enzyme, most likely the ATP-grasp enzyme fsqD, is responsible for activation of tyrosine (Probable).  Three additional enzymes encoded by the fsq cluster, the N-methyltransferase fsqC, the phenol 2-monooxygenase fsqG and the FAD-dependent oxidase fsqB, catalyze the formation of the isoquinoline ring system in the fumisoquins (PubMed:27065235, PubMed:30194285).  FsqB converts the fspF thiolation domain-bound (2S,4S,5S)-2-amino-6-(3,4-dihydroxyphenyl)-4-hydroxy-5-(methylamino)hexanoyl into isoquinoline (PubMed:27065235, PubMed:30194285).  The cyclization most likely proceeds via a two-step mechanism, beginning with FAD-dependent oxidation of the methyl group to an iminium species followed by electrophilic attack on the deprotonated phenol (Probable).
What are the official names of this protein?
ATP-grasp enzyme fsqD, Fumipyrrole biosynthesis protein C, Fumisoquins biosynthesis protein D.