PharMolix/UniProtQA huggingface dataset:
Protein: TRIC_SULTO
Sequence: MFYNFLLYLVIHVNYALDALTFNKFLSLDGIVSWPMIIKDRVYFLSDHEGISNLYSVNLEGKDLTKHTNFTEYYCRNASSDGRRIVFQNSGDIYLYDPEKQELKLLDIDLPTDRKKKQGKFVEVLDYTTEAIANDKYLSLISRGKVFLMRHWDGPAVQLGEKQGVRYKQIQLLPNGDTVVLDTNDDKLTFLSKDGSIKKLNVDLGRIERIKVSPDGKKILISNNRLELWLYEVDTTNLRLIDKSEYDVISQMDWHPDNEWFAYTFPESYSTQSIKLAHISGKVIRITSPYGYDFSPSFDPDGRYLYFLSARHLDPTNDKVIFNMSFQRVIKPYLVVLSNTYSPFNQSLEETTSDKKVEIEGIEDRVIPFPVDEDYYIRIEGAKNNKVFLFSLPIKGYRYPGETLGKLEVFDLDSKTKELYADNVKSFSLTIDKGKILILFKDSIRLFDVNTKPDLNATGKKGGIVDLSRIKVYVDPEREWKQMFREAWKLMQQNYWKPDGLKDWESVLLKYEKLIDRISTRYELSDLIQEMQGETKTSHSYEMPYDYDTAEPLPIGGLGADYEYDKENKCYKIARIYVGDPTNENERSPLRDPGVQLNIGDCIKAVDGEEVKYNILSYLVNKDQVVLDVITKGKTKRVTVKLLKDEKFLIYRYWVEKNRQYVHEKSKGKLGYVHIPDMMYQGFAEFYRLFLSEFHREGLIVDVRFNRGGFISGLILEKLLLKRMGYVVRRNGKELPHPFFSSPGVIVAITNQYAGSDGDIFSYLFKKYKLGILIGRRTWGGVIGINVRDRLADNSAVSQPEFAVHFHDIGLKIENYGVDPDIEVDIKPEDYANGRDPQLDTAIELALKQLEEKS
What is the function of this protein?
Degrades oligopeptides in a sequential manner.
What are the official names of this protein?
Putative Tricorn-like protease C-terminal subunit.
What is the protein family that this protein belongs to?
Belongs to the peptidase S41B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRB_CLOBK
Sequence: MNQFKVISKFNPTGDQPKAIKSIAKGIEKREKFQTLIGVTGSGKTFTMANIIEKVQKPTLVLAHNKTLAAQLCSEFREFFPNNAVEYFVSYYDYYQPEAYVAQSDTYIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGNPEEYKKLTISLREGMEKDRDEIIKKLVEIQYERNDIDFSRGTFRVKGDVLDIFPASSSSKAVRVEFFGDEIDRIKEFDVLTGETITKLKHISIFPASHFATSKDRLEVAIKDIEEELEERVKELVSQDKILEAQRLKQRTNFDIEMMREVGYCTGIENYSRVLDGRAKGTPPQTLLDYFPQDFLLFIDESHVTLPQVKAMQAGDKSRKDSLVEYGFRLPCAYDNRPLTFKEFENKLNQVVFVSATPAKYELEYSTNTAEQVIRPTGLLDPEIIVKPVKGQIDDLYTSIQETIKRGFRILVTTLTKKMAEDLTDYLKEMGVKTRYLHSDIDTIERMKIIHDLRKGEFHVLVGINLLREGLDIPEVALVTILDADKEGFLRSETSLIQTVGRAARNSESKVIMYGDVITKSMEKTIKETNRRRKIQMEYNEEHGIVPKTIIKDIREVIQISDIAEERKEYDNLNEALKSYNNDIDKLIEKYEEEMKEAAQNLQFEKAAHLRDVIYKLKKDKETEL
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HOS3_YEAST
Sequence: MSSKHSDPLERFYKQFQAFVQNNPNVISAARAAAQIPESAKAVVVLSPYSLQHVFPREWVTKSYRKTIVERPERLLASSMGISAAITMYPSLFTLKSSHQRKGSLMAPHVLKVHGSSWPAELIELCQMADAKLLKGEIEVPDTWNSGDIYLSSKTIKALQGTIGAIETGVDSIFKGPSAEHISNRAFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTYNVTHVVVLDFDLHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMHDINSFPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTKYRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTSMQRHSVNVPTSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAICSGVFAHLIGLQNQDWVKEWGSEQVVKEIVRGCKPAWKPYKTKRAKDVIRIWAEEVIRLGRAMIPEFDDIIFKDAVNSAPSNSLLKATVEPASTSTIAQRIIRSHRSNASPEKELHENKPRSTEKQEQREIRSDTKVKQLSSNNRAAETQIPFLQQEFSSEDEDEEYVYDEELNKTFNRTVEDITIDDISRHLETLEIEKKGDEDSDHELKEKNWKNSHQRRLQGNGMYKIPSNTKPHRIRQPQNANTPTYDDSDISMISHVSRKHTTRSGGRW
What is the function of this protein?
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).  Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.  Histone deacetylases act via the formation of large multiprotein complexes (By similarity).
What are the official names of this protein?
Histone deacetylase HOS3.
What is the protein family that this protein belongs to?
Belongs to the histone deacetylase family. HD type 1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y4106_PSEAE
Sequence: MTLIDNAAGLGLRRGLLPQLLAMAPGAVDFLECAPDNWIGVGGAFGADLERLVERIPLTCHGLSLSLGGSTPLDAAFIEQTRRFLVRHRVALYSEHLSYCSDDGHLYDLLPLPFTEAAVRHVAARIREAQERLERRIAVENISYYAAPYREMSEIEFVNAVLDEADCDLLLDVNNLFVNACNHGYDALDFLVRLPPGRVAAYHVAGHYDEAPDLKIDTHGAAVKPGVWALLGAAYRRFGVRPTLLERDFNYPPLGELLLEVEQIRQWQRDEGRRHG
What are the official names of this protein?
UPF0276 protein PA4106.
What is the protein family that this protein belongs to?
Belongs to the UPF0276 family.
Protein: NCF1C_HUMAN
Sequence: MYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENHQGTLTEYCSTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIADYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
What is the function of this protein?
May be required for activation of the latent NADPH oxidase (necessary for superoxide production).
What are the official names of this protein?
Putative neutrophil cytosol factor 1C, NCF-1C, Putative SH3 and PX domain-containing protein 1C.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KPBB_HUMAN
Sequence: MAGAAGLTAEVSWKVLERRARTKRSGSVYEPLKSINLPRPDNETLWDKLDHYYRIVKSTLLLYQSPTTGLFPTKTCGGDQKAKIQDSLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQDPRPTTCLHSVFNVHTGDELLSYEEYGHLQINAVSLYLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNTDAALLPCISYPAFALDDEVLFSQTLDKVVRKLKGKYGFKRFLRDGYRTSLEDPNRCYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVQEYQDLLTPVLHHTTEGYPVVPKYYYVPADFVEYEKNNPGSQKRFPSNCGRDGKLFLWGQALYIIAKLLADELISPKDIDPVQRYVPLKDQRNVSMRFSNQGPLENDLVVHVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQQELVKAYLQLGINEKLGLSGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVFLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAALKKGIIGGVKVHVDRLQTLISGAVVEQLDFLRISDTEELPEFKSFEELEPPKHSKVKRQSSTPSAPELGQQPDVNISEWKDKPTHEILQKLNDCSCLASQAILLGILLKREGPNFITKEGTVSDHIERVYRRAGSQKLWLAVRYGAAFTQKFSSSIAPHITTFLVHGKQVTLGAFGHEEEVISNPLSPRVIQNIIYYKCNTHDEREAVIQQELVIHIGWIISNNPELFSGMLKIRIGWIIHAMEYELQIRGGDKPALDLYQLSPSEVKQLLLDILQPQQNGRCWLNRRQIDGSLNRTPTGFYDRVWQILERTPNGIIVAGKHLPQQPTLSDMTMYEMNFSLLVEDTLGNIDQPQYRQIVVELLMVVSIVLERNPELEFQDKVDLDRLVKEAFNEFQKDQSRLKEIEKQDDMTSFYNTPPLGKRGTCSYLTKAVMNLLLEGEVKPNNDDPCLIS
What is the function of this protein?
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.  The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
What are the official names of this protein?
Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the phosphorylase b kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: RBFA_BACAA
Sequence: MKLRANRVGEQMKKELGDIISRKIKDPRVGFVTVTDVQVSRDLQIATVYISVLGDEEQKENTLKGLAKAKGFIRSEIGQRIRLRKTPEISFEFDESIGYGHRIDTLLHEINKEGKREE
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes).  Required for efficient processing of 16S rRNA.  May interact with the 5'-terminal helix region of 16S rRNA.
What are the official names of this protein?
Ribosome-binding factor A.
What is the protein family that this protein belongs to?
Belongs to the RbfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SRP19_ARATH
Sequence: MDSGTINIKKWVVIYPVYINSKKTVAEGRRISVSKSCENPNCIEISDCCKHLKLPSAVEIDKAYPRDFMQVGRVRVQLKREDGTLLNPAITSRKHLMQKIAELVPRHPERVKKQEAQKAKKQEPQATTSTSGTSSKSGKGGKKKR
What is the function of this protein?
Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) (By similarity).  Binds directly to 7SL RNA (By similarity).  Mediates binding of SRP54 to the SRP complex (By similarity).
What are the official names of this protein?
Signal recognition particle 19 kDa protein, SRP19.
What is the protein family that this protein belongs to?
Belongs to the SRP19 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: SYR_ECO45
Sequence: MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGNYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALASDRLGVAMPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVGDWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGLDTLGIETVERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCEM_SALTY
Sequence: MRTLRIGIVGLGGIAQKAWLPVLTNTAGWTLQGAWSPSRDKALRICESWRIPYVDSLANLASSCDAVFVHSSTASHYAVVSELLNAGVHVCVDKPLAENLRDAERLVALAAQKKLTLMVGFNRRFAPLYRELKTRLGTAASLRMDKHRTDSVGPHDLRFTLLDDYLHVVDTALWLAGGEARLASGTLLTSESGEMCYAEHHFSADKLQITTSMHRRAGSQRESVQAVTDGGLYDVTDMREWREERGQGILIKPIPSWQTTLEQRGFVGCARHFIDCVQNQTVPETAGEQAILAQRVVEALWRDAISE
What are the official names of this protein?
Putative oxidoreductase YceM.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: PTXC_STUST
Sequence: MSSHYDVQALPAEQREHILRGFGLGWWRQLGQVAIVFGVVLLACWYVGLLDATTLLNGLPSIATLAGEAMPPDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARNTAPHPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVGKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLRKHFK
What is the function of this protein?
Probably forms part of a binding-protein-dependent phosphite transporter.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Phosphite transport system permease protein PtxC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
Protein: GRGG_PENSQ
Sequence: MTGFAEIIISPASFIYFPLLILVGHALIFILNTLRPKAFPPGPRGLPGLGNLLQVDRIFPFLTYGKWAKDYGSDTPLGVKKGATNVVVLNSSRLVRELFEKRGAVYSDRPWQFMNNTWIFKDDLKAAIFQNSSPWLTSWRRDFNKNFGPAAITRLRPIYEAETARLLVKLLEAPTASGKDLEAILVCWMMSVPCLGVCGRRPDSMGDHGFEIKQFRHCSDEYATLVAPNAGDLFPFLRYLPEFFGMAEWKERARAVREAVLNTGTQFLSAAREQRAALDEGKSIAWESVLAKMLREQREKNDDMFTVTDMGNTAFHIVSAATNTSLAVFSIMLLILAKDPQLQQRVRNEVLEVSGGATPTATDLSSLKYTEAFWNEVHRWRPVAPQGVAHAPSQDDIYNGHRIPKGTAIIMNVWNIHHSEEDYDEPEEFIPERFLQHPLGLRSDHTLDAAHLEASASRVTWDFGAGRRICPGMHSAKHSLLLGLAKVLWAFDILPPEGKEIDLSLETGFVQEIALHPKELNVVLKLRDGRTKQDLMDHYSQTYAAEAEVMGWKDGLYQ
What is the function of this protein?
Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of gregatin A, a fungal polyketide featuring an alkylated furanone core (PubMed:32275405).  The PKS grgA synthesizes C11 and C4 polyketide chains in the presence and absence of the trans-enoyl reductase grgB, respectively (PubMed:32275405).  The polyketide transferase grgF is then responsible for the fusion of the two carbon chains to produce the furanone skeleton of gregatin A (PubMed:32275405).  Next, the cytochrome P450 monooxygenase grgG performs the oxidative cyclization to furnish the gregatin scaffold and leads to the formation of desmethylgregatin A.  In this transformation, grgG initially abstracts a hydrogen atom from C-8 to generate a substrate radical, from which one electron is transferred to the iron-heme center to yield a carbocationic species.  Heterocyclization along with double-bond isomerizations provides desmethylgregatin A with the furanone ring.  Alternatively, grgG might provide hydroxylation at the C-8 radical, which is followed by dehydration to give the cyclized desmethylgregatin A (PubMed:32275405).  Finally, the O-methyltransferase grgD methylates the carboxyl group of desmethylgregatin A to provide gregatin A (PubMed:32275405).
What are the official names of this protein?
Cytochrome P450 monooxygenase grgG, Gregatin A biosynthesis cluster protein G.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: LSD1_SCHPO
Sequence: MMDLSSKDALSDVLKDTHAQSSDPSLWAIFGHQSSDNVHEGGNESVSVEQEIFDLSQLSERPVSETVSKASIPTNINGLSQVKPSALEKSQEVLSLQKLPIKGRRPAGRRGRPALNTSNSLERNGTRYVSAEAPISVKSSIPAIPRVTFERLCYESAIASNLPPNALSPLEAEMLSEILENPTWLSLYLSIRNGICYLWHRNPTLYVSFNEALGIVREKKAFPLASLAFEFLSRNGHINYGCIYIISSLKLDESLSQKTVAIIGAGMAGISCARQLTNLFAQYEQDFLSRGEKPPRIVIYEASERLGGHIYTHMVPLSDNEVSEKSSLATTVNATNECMVNLLTDSLIGMPTLDSDPLYIISSQQLSLDAVHTRNREFILHDIENGRIDTEHVQRIFRLFDALLFYFNASASKQPLHSLITPPEQEFIQKLDQIGWYISIEAFPLQIKDTLSEFLGNSANTLTSLLHLTVLDLKIFEWFKEYLSQSLSVSLENVYPGSIPNLNLLLGENVASYSFKHGMADMLNSLASTPSPLPILFDQCVHTVKLEDNTVNLSFVNETTVSVDKVVICIPMDKLNTHLITFEPPLEEKKLKAIDRCHFTNVKKVILIFKTQFWEPNISIFGSLPQDSGRNFIFNDCTRFYEHPTLSVFVKVEGIDFMKDDDIVNGIVSQLKKVYKPKSEAINPIRTIISNWENNSYTNHSSYQISNLFLEEDYAILSEPIDNTVFFASEAISQKNSGSIRGAFDSGILAARDVLASLIGNVVLPNTLVIEENLEQPRKTYGTKRNAQQALGKEGERENKEKRISYHTEYLRLRQKRLDKEQQECDLLIAELLGPSPVPPSRPSANPYLLYQKTQWHVCKTLADQDKQRVTGDPEARATKNEIRAKLGKTWRALDSLGKQPWVDEINARRANYSTRLEEYQRQINSYNVRVAQIKSEHQRRCESQPIPEDEAKLKLLAEQEDEHLHPEKEGMSVENSDDDYHDDLDYEDSISEVFPDNFS
What is the function of this protein?
Catalytic component of the SWM histone demethylase complex that specifically demethylates H3K9me2, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.  Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed.  Has a role in regulating heterochromatin propagation and euchromatic transcription.  Also has a gene activating role.
What are the official names of this protein?
Lysine-specific histone demethylase 1.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFEB_ECOL5
Sequence: MQYEDENGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGTLSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKADLERLFRLLTQRFAFLTQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKMTRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANPDSQNAKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDKQTGAPLGMLHEHDVPDYASDPEGKVIALDSHIRLANPRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKPIGGGYFFALPGVKDANDYLGSALLRV
What is the function of this protein?
Involved in the recovery of exogenous heme iron.  Extracts iron from heme while preserving the protoporphyrin ring intact.
What are the official names of this protein?
Deferrochelatase, Peroxidase EfeB.
What is the protein family that this protein belongs to?
Belongs to the DyP-type peroxidase family. EfeB subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: RSXC_SALPA
Sequence: MLKLFSAFRKDKIWDFDGGIHPPEMKSQSNGTPLRQVPLAPRFVIPLKQHIGAEGELCVSVGDRVLRGQALTRGRGRMLPVHAPTSGTVIAIAPHSTAHPSALAELSVIIDADGEDRWIEREGWSDYRAHSREALIERIHQYGVAGLGGAGFPTGVKLQGGGDKITTLIINAAECEPYITADDRLMQDCAAQIVEGIRILAHILQPREVLIGIEDNKPQAISMLRAVLADAHDISLRVIPTKYPSGGAKQLTQILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVVDGEPITERVVTLTGEAISRPGNVWARLGTPVRHLLNDAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSVTEMGAPQEEKSCIRCSACADACPADLLPQQLYWFSKGQQHDKATAHHIADCIECGACAWVCPSNIPLVQYFRQEKAEINAIRLEEKRAAEAKARFEARQARLEREKAARLARHKSAAVQPAAKDQDAIAAALARVKEKQAQATQPVVIQAGSLPDNSAVIAAREARKAQARAKQAAHPMADSAISGDDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQAGSEPAEPVDPRKAAVEAAIARAKARKQEQQTVSEPVEPADPRKAAVAAAIARVQAKKAAQQQVVNED
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rsx electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VPR_SIVGB
Sequence: MGQKRDEQVSEDQGPPREPYNQWLADTMEEIKEEARKHFPLIILNAVSEYCVQNTGSEEEACEKFITLMNRAIWVHLAQGCDGTFRERRPQLPPSGFRPRGDRL
What is the function of this protein?
Stimulates gene expression driven by the HIV-2 LTR.  Prevents infected cells from undergoing mitosis and proliferating, by inducing arrest or delay in the G2 phase of the cell cycle.  Cell cycle arrest creates a favorable environment for maximizing viral expression and production (By similarity).
What are the official names of this protein?
Protein Vpr, R ORF protein, Viral protein R.
What are the subcellular locations of this protein?
Virion. Host nucleus.
Protein: PNP_RHIWR
Sequence: MFDTKKVEIQWGGQTLTLETGRVARQADGAVLATLGETVVLCAVTAARSVKEGQDFFPLTVHYQEKYFSSGRIPGGFFKRERGATEKETLVSRLIDRPIRPLFPEGFYNEINVIAQVLSYDGENEPDILAMIAASAALTISGVPFMGPIGAARVGYKDGEYLLNPTDADVAAGDLDLVVAATHDAVMMVESEAKELSEEVMLGAVMFAHKASQDVIKAIIKLAEKSAKDPWEMAPQADLSAAKTKLKKLVGKDITAAYKLTNKSARSSALNEARAKAKEAFADATPQDQMAAIKLVKKLEAEIVRTAILKDGRRIDGRDTRTVRPIVAEAHFLPRAHGSALFTRGETQSISTCTLGTKESEQMIDGLNGLRYEHFMLHYNFPPYSVGEVGRFGAPGRREVGHGKLAWRALHAVLPTKEEFPYTIRLTSDITESNGSSSMATVCGGSLAMMDAGVPIKRPVSGIAMGLILEGKDFAVISDILGDEDHLGDMDFKVAGTSEGITTMQMDIKIAGITEEIFKTALLQAKEGRAHILGEMAKALDHTRTELSAHAPRIETMSVPKDKIRDIIGTGGKIIREIVATTGAKVDIDDDGTVKISSSDTAQIEAARNWIIGIVAEPEVGKIYTGKVVNLVDFGAFVNFMGGKDGLVHVSEIKNERVEKVADALSEGQEVKVKVLEIDNRGKVRLSMRVVDQETGEELPDTRPPREERPRGDRGDRGDRGPRRDGDRRREGGDRGPRRDRGDRGDRPRRERSEGGDEGPAPDFAPAFLTRDDD
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LAS2_MACFA
Sequence: MAKSKTKHRLCSRESSVSSLLASCSLSDSNSSNSDGSYHYKDKLYRSASQALQAYIDDFDLSQMYPGTSTGKINIDEDFTNMSQFCNYIYKPNNAFENLDHKKHSNFISCRRQTINDIDSMSLTTDDLLRLPADGSFSYTYVGPSHRTNKKNKKCHGRLGSSDVEKNPNFQGPSTPVGDKIELLILKAKRNLEQCTEELPKSMKKDDSPCSLDKLEAERSWENIPVTFKSPIPVNSDDSPQQTSRAKSATGVLEDFLNNDNQSCTLSGGKHHGPVEALKQMLFNLQAVQERFNQNKATEPKEEIKQVSEDDFSKLQLKERQF
What is the function of this protein?
Might play a role in cell proliferation.
What are the official names of this protein?
Lung adenoma susceptibility protein 2 homolog.
What are the subcellular locations of this protein?
Secreted.
Protein: CRBL_VESTR
Sequence: FLPILGKILGGLL
What is the function of this protein?
Mast cell degranulating peptide.  Induces the chemotaxis of neutrophils.
What are the official names of this protein?
Vespid chemotactic peptide T, VESCP-T, Ves-CP-T.
What is the protein family that this protein belongs to?
Belongs to the MCD family. Crabrolin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_ALISL
Sequence: MSDNLKIGLQYLTPKHALTRLAGKLASAKMGWLTTAVIKWFIKQYNVEMSEAKNPDPEAYSTFNNFFVRELEDGARPINDDENVISHPADACVSQFGPITDGQLVQAKGHVYSAQELLGGDAELAEEFIGGEFATLYLSPRDYHRVHMPCDATLRKMVYVPGDLFSVNPLTAENVPNLFARNERVVCIFDTEFGPMAQVLVGATIVGSIETTWADTVTPPTGPAVKTWHYPLSGDDVICFKKGEEMGRFKLGSTVINLFAPNSITFDESMKNGVPTRLGTPFAHIAK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MACB_MARN8
Sequence: MSPRPLIELQDITRSFGEGELAVPVLKGIDLKIWPGEFVAIMGPSGSGKSTLMNILGCLDQPSAGQYRFNGRDVSALDRDELARLRRDAFGFVFQSYNLLPGMTARENVEIPAIYAGMAPAERHARAERLLTGLGLGERLSHRPAQLSGGQQQRVSIARALMNGGQLIFADEPTGALDSKSSQEVIRLLTDLSRQGHTIILITHDPDVAKVARRQIRIADGELVEDTGAEMPSAQIPETDQNGRRHSRLGDWQEALKSAVRSLHSNLFRTALTLLGIVIGVASVITMLAIGEGARKDVVDRISTMGSDLLLVRPGGPDQRGGRWSVTTLVPSDFKAINEIEGVLAAIPELTGGQTLRYSNRDHSAEINATSFRFPVARQWPVVEGTFFSAQDEASYAAVAVLGKTTANALFPDESPLGKHLMVNNVLFQVIGVMDEKGASPMGQDQDDVVFVPYTTGSLRIFGQTHLRNITVAVADIDRMDEIEALIHDTLMARHGIEDFTIRNMASLIETISETQNTLTWLLGSIAAISLLVGGIGVMNIMLVSVTERTREIGIRMATGARAWNILQQFLTEAWLVSAIGGLIGVVIGIAATRIIGSLGTPIHMTLLPMALAFGCAFATGLLFGFLPARKAAHLDPVHALASE
What is the function of this protein?
Part of the tripartite efflux system MacAB-TolC.  MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation.  Confers resistance against macrolides.
What are the official names of this protein?
Macrolide export ATP-binding/permease protein MacB.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DAPEL_LIGS1
Sequence: MTLQENELIKIRRDLHQIPEIGLEEYETSDYLLKIINGLPQENLEIKRWKTAILVHLNGENKNYTIGYRTDIDGLPVEEKTGLPFSSKHEGRMHACGHDIHMTVALGVLSYFASHRPKYNMTFIFQPAEENASGGMKLYQSGELDEWMPDEIYALHDNPQLPAGTIGCRKGTLFAGTCEIHVKFIGKSGHAAYPHQANDMVVAGAQFVNQIQTIVSRNVDPIQSVVVTLGHFSAGTTGNVISGVCQIDGTIRALTQENNLLIQKRVRTIAEGIAHSFDCELEIDLHQGGYYPVENDDNTTEAFINYMKNEDDVDFVETLPAMTGEDFGYLISKIPGTMFWLGVDSPYSLHSEYLAPKEESIMLGVNAITGYLKNRQESLNK
What is the function of this protein?
Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate.
What are the official names of this protein?
N-acetyldiaminopimelate deacetylase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. N-acetyldiaminopimelate deacetylase subfamily.
Protein: TX24A_MACGS
Sequence: MKVFSFTVVVVMILSLSAFVLAGDEGDVMKKIVAMEEAVEERACLAEYQKCEGSTVPCCPGLSCSAGRFRKTKLCTK
What is the function of this protein?
Inhibits Kv11. 1/KCNH2/ERG1, Kv1. 1/KCNA1 and Kv1. 3/KCNA3 voltage-gated potassium channels and Nav1. 7/SCN9A voltage-gated sodium channels (PubMed:29483648).  In vivo, intracranial injection into mice causes lack of coordination for 10 min, followed by fast recovery.
What are the official names of this protein?
U11-hexatoxin-Mg1a, U11-HXTX-Mg1a, Neurotoxin magi-10.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 02 (plectoxin) family. 04 (U16-lycotoxin) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFPL_KLEP3
Sequence: MPRANEIKKGMVLNYNGKLLIVKNIDIQSPSARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRFVDFSYVDGNEYVFMDKEDYTPYTFTKEQIEEELQFIPEGGMPDMQVLTWDGQLLALELPQTVDLEIIETAPGIKGASASSRTKPATMSTGLVIQVPEYLTTGEKIRIHIEECRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.