PharMolix/UniProtQA huggingface dataset:
Protein: ENLYS_LAMBD
Sequence: MVEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTDYSDHPRKLVTLNPKLKSTGAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIDV
What is the function of this protein?
Endolysin with transglycosylase activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles.  Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.
What are the official names of this protein?
Endolysin, Lysis protein, Lysozyme, Transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 24 family.
What are the subcellular locations of this protein?
Host cytoplasm. Note=The endolysin is cytoplasmic, but can reach the periplasmic space with the help of the holins which disrupt the host cell membrane.
Protein: RF2_MYCVP
Sequence: MDPDRQADIAALDATLTTVERVIDVDGLRGRIEQLEKDASDPQLWDDQARAQKVTSDLSHAQGELRRIEELRGRLEDLPVLYELAAEEGGSDEVAEADAELTKLREDIEAMEVRTLLSGEYDEREALVTIRSGAGGVDAADWAEMLMRMYIRWAEQHKYPVEVFDTSYAEEAGIKSATFAVHAPYAYGNLSVEQGTHRLVRISPFDNQNRRQTSFADVEVLPVTETTDHIEIPEGDVRVDVYRSSGPGGQSVNTTDSAVRLTHIPTGIVVTCQNEKSQLQNKVSAMRVLQAKLLERKRLEERAEMDALKGDGGSSWGNQMRSYVLHPYQMVKDLRTEYEVGNPSAVLDGDIDGFLEAGIRWRNRKDDE
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECF_GEOSW
Sequence: MFLTHLSLKNYRNYESETIEFANNVNIILGENAQGKTNMMEAIYVLAMAKSHRTTNDKDLIRWDEDYAKIEGKAMKKNGALSLELIISKKGKKAKCNHIEQQRLSQYVGHLNIVMFAPEDLNLVKGSPQVRRRFVDMEIGQVSPVYIHDLSQYQKLLQQRNHYLKMLQTREQQDETVLDILTEQLIPLAAKITLKRYEFLLLLQKWAAPIHHEISRGLETLQIQYRPSVDVSEKIELSRIIEAYSEKFATIKEREIQRGMTLAGPHRDDIAFSVNGKDVQIFGSQGQQRTTALSIKLAEIELIFSEIGDYPILLLDDVLSELDDFRQTHLLDTIRKKVQTFVTTTSIEGIEHDIIKEAAIYKVHSGHITAPLCD
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TUSA_VIBVY
Sequence: MSFNPELATKTLEAEGLRCPEPVMMVRKTIRTMQDGEVLLVKADDPSTTRDIPSFCRFMDHQLIAAQTDELPYQYLIKKGL
What is the function of this protein?
Sulfur carrier protein which probably makes part of a sulfur-relay system.
What are the official names of this protein?
Sulfur carrier protein TusA.
What is the protein family that this protein belongs to?
Belongs to the sulfur carrier protein TusA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_METRJ
Sequence: MNALDLPKAPHETRVVVAMSGGVDSSVVAGLLKRQGFDVVGVTLQLYDHGAASHRKGACCAGQDIHDARAAAEHLGIPHYVLDYEDRFRDEVIEKFAESYLAGETPIPCVECNRTVKFRDLLGLARDLDADALATGHYVASRALPGGGRALHRALDPARDQSYFLYATTAEQLDFLRFPLGEMEKTETRALAKELGLSLAEKPDSQDICFVPQGRYSDVIARLRPDAARPGEIVDLDGHVLGRHDGIVHYTVGQRKGLGLSGPEPLYVVRLEPDAARVVVGPRTALATTRIRLSDLNWLGEGPAEAVRDLPVAVRVRSTRPPRPATLTVGPDGAVEVVLAEPEDGVSPGQACAIYADDGPRARVLGGGTIRRVDALSARPREAA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPT3_BOVIN
Sequence: MDEKPSTRKSPEFCSLRYGLALIMHFSNFTMITQRVSLSIAIIAMVNRTQQPGLFNTSTERPLAFTFNHSNRSIKEFNTAEVSVYEWSPETQGIIFSSINYGIILTLIPSGYLAGIFGAKQMLGAGLLISSLLTLFTPLTADFGVILVIVIRTVQGMAQGMAWTGQFTIWAKWAPPLERSKLTSIAGSGAAFGSFIILCVGGLISQALGWPFIFYIFGSIGCVCCLLWFTVIYDDPLHHPCISIREKEHIVSSLAQQSSSPRRSVPIKSMVRCLPLWAIFMGFFSHFWLCTIIITYLPTYISSVLHVNIRDSGVLSSLPFIAAASCTILGGQLADFLLSRNLLRLITVRKLFSSLGLLLPSLCAVALPFVASSYTTTIILLILIPGTSNLCDSGFIINTLDVAPRYASFLMGISRGFGLIAGIISSTATGFLISQDSVSGWRNVFFLAAAVNMFGLVFYLTFGQAEIQHWAKERTLTRL
What is the function of this protein?
Important for the resorption of phosphate by the kidney.  May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (By similarity).
What are the official names of this protein?
Sodium-dependent phosphate transport protein 3, Na(+)/PI cotransporter 3, Sodium/phosphate cotransporter 3, Solute carrier family 17 member 3.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: YSCQ_YERPE
Sequence: MSLLTLPQAKLSELSLRQRLSHYQQNYLWEEGKLELTVSEPPSSLNCILQLQWKGTHFTLYCFGNDLANWLTADLLGAPFFTLPKELQLALLERQTVFLPKLVCNDIATASLSVTQPLLSLRLSRDNAHISFWLTSAEALFALLPARPNSERIPLPILISLRWHKVYLTLDEVDSLRLGDVLLAPEGSGPNSPVLAYVGENPWGYFQLQSNKLEFIGMSHESDELNPEPLTDLNQLPVQVSFEVGRQILDWHTLTSLEPGSLIDLTTPVDGEVRLLANGRLLGHGRLVEIQGRLGVRIERLTEVTIS
What is the function of this protein?
Component of the Yop secretion machinery.
What are the official names of this protein?
Yop proteins translocation protein Q.
What is the protein family that this protein belongs to?
Belongs to the FliN/MopA/SpaO family.
Protein: RL32_XANC5
Sequence: MAVQKSRVTPSRRGQRRSHDALTAKQLSTDPTSGEIHLRHHITADGYYRGKKVIATKSSAVQED
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: ESPL_MYCTU
Sequence: MSMDELDPHVARALTLAARFQSALDGTLNQMNNGSFRATDEAETVEVTINGHQWLTGLRIEDGLLKKLGAEAVAQRVNEALHNAQAAASAYNDAAGEQLTAALSAMSRAMNEGMA
What is the function of this protein?
Probably plays a role in host phagosome maturation arrest (PubMed:20844580).
What are the official names of this protein?
ESX-1 secretion-associated protein EspL.
Protein: RAE1E_MOUSE
Sequence: MAKAAVTKRHHFMIQKLLILLSYGYTNGLDDAHSLRCNLTIKDPTSADLPWCDVKCSVDEITILHLNNINKTMTSGDPGKMANATGKCLTQPLNDLCQELRDKVSNTKVDTHKTNGYPHLQVTMIYPQSQGQTPSATWEFNISDSYFFTFYTENMSWRSANDESGVIMNKWKDDGDLVQQLKYFIPQCRQKIDEFLKQSKEKPRSTSRSPSITQLTSTSPLPPPSHSTSKKGFISVGLIFISLLFAFAFAM
What is the function of this protein?
Acts as a ligand for KLRK1.
What are the official names of this protein?
Retinoic acid early-inducible protein 1-epsilon, RAE-1-epsilon.
What is the protein family that this protein belongs to?
Belongs to the NKG2D ligand family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: KAP0_MOUSE
Sequence: MASGSMATSEEERSLRECELYVQKHNIQALLKDSIVQLCTTRPERPMAFLREYFERLEKEEARQIQCLQKTGIRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV
What is the function of this protein?
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
What are the official names of this protein?
cAMP-dependent protein kinase type I-alpha regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the cAMP-dependent kinase regulatory chain family.
What are the subcellular locations of this protein?
Cell membrane.
Protein: PYRR_ACTSZ
Sequence: MEKIIIDEDQFMRTISRISHEIIEKHKNLNDLVIVGIKRRGAEIAELVKRKINELTGSRIPSIDLDITFYRDDLEYAEPNSQSPVYNGSSDFISVQNKTVILVDDVLFTGRTIRAALDALVDFGRASKVELVIFVDRGHRELPIRADYVGKNVPTSRSEKVQVRTMKFDGCYEVALLSK
What is the function of this protein?
Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
What are the official names of this protein?
Bifunctional protein PyrR.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
Protein: GRAG_MOUSE
Sequence: MPPILILLTLLLPLRAGAEEIIGGHEVKPHSRPYMAFIKSVDIEGKKKYCGGFLVQDDFVLTAAHCRNRSMTVTLGAHNIKAKEETQQIIPVAKAIPHPAFNRKHGTNDIMLLKLESKAKRTKAVRPLKLPRPNARVKPGDVCSVAGWGKTSINATKASARLREAQLIIQEDEECKKLWYTYSKTTQICAGDPKKVQAPYEGESGGPLVCDNLAYGVVSYGINRTITPGVFTKVVHFLPWISTNMKLL
What is the function of this protein?
This enzyme is probably necessary for target cell lysis in cell-mediated immune responses.
What are the official names of this protein?
Granzyme G, CTL serine protease 1, MCSP-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Granzyme subfamily.
What are the subcellular locations of this protein?
Cytolytic granule.
Protein: SURE_HELAH
Sequence: MKKILLTNDDGYHAKGIKALEQALEKMAEIYVVAPKHEKSACSQCITITTPLRAEKIKGKEGRHYRIDDGTPSDCVYLAINELFKHVSFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNIFTKGYPLKGRKLLNVNIPNCSLQEYKGECITPKGYRVYKKEVHRRTDPKNESYFWLGLHPLEWQKRENEERFSDFDAVVSNHVSITPLNLDLTSYSDLKSLESWHRGMLK
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_PEDPA
Sequence: MSQLKVTLIKSAAHRLPKQRTIVKELGLGRVNSSVVLPNNEATRGAIFHIAHLIEVEEVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: RPOC_SHESM
Sequence: MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEENYLDALEEYGDEFEAKMGAEAVLELLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLMEAFHTSGNKPEWMILKVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMYFMSVAEVEKAYATGAAELHARVKVRITETVIGDNGERTEQRRIVDTTVGRALLSQILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRYATISGASVGIDDMVIPAEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVAVDVMYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEVIVRSVITCDTDFGVCAACYGRDLARGHLINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKLHNAKYVTNTDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEASVEAGDIIANWDPHTHPIITEVAGSIKFVDMIDGVTMTRQTDELTGLSSIVILDVGQRGSAGKEMRPMIRLVGADGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDALARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGEHYEEMIPKWRNLNVFEGEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCVITSAGDSEFLEGEQVEVSRVKIANRELVEQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAGTGYAYHKTRNDARAKKDEPVVVNKITASEAEQNLADLLNLAGSQD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: MIAB_ANADF
Sequence: MTDLVSLSPKPASAPGTRPAAARKVYVHTFGCQMNASDSDRMIELLGRHAFARAETPDDADLILLNTCAVREKAEQKLLSALGRYREVKARRGALIAVSGCVAQQEKDRLLARVPYVDFVFGPDNIGKLPEMVARAERERFAETGWMDSQDYVFPQADPEAARGRPTAFVTAMKGCDNVCAFCIVPHTRGREVSRAFPEIVAECASLAEVGVREVTLIGQNVNSYAGGCTFAELLRRVAAVPGIARIRFTTSHPHDLSDALVAVFRDEPKVMPHFHLPVQSGSDAVLARMRRDYTVAEYLDRFDRLRAARPGIAITTDFIVGFPGEGEADFEGSLALLERARFEQSFSFLFSPRPKTVANLRLGTAPEWQEIPRAVAVERLERLQAAQRRIAAAALAAELGKVVEVLVEGASDEPGERLGRTPENRVVHLAADEAGAPTGALVRARITRAGGSSLSGTPA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PAI1_RAT
Sequence: MQMSSALTCLTLGLVLVFGKGFASPLPESHTAQQATNFGVKVFQHVVQASKDRNVVFSPYGVSSVLAMLQLTTAGKTRQQIQDAMGFNISERGTAPALRKLSKELMGSWNKNEISTADAIFVQRDLELVQGFMPHFFKLFRTTVKQVDFSEVERARFIINDWVERHTKGMISDLLAKGAVNELTRLVLVNALYFNGQWKTPFLEASTHQRLFHKSDGSTISVPMMAQNNKFNYTEFTTPDGHEYDILELPYHGETLSMFIAAPFEKDVPLSAITNILDAELIRQWKSNMTRLPRLLILPKFSLETEVDLRGPLEKLGMTDIFSSTQADFTSLSDQEQLSVAQALQKVKIEVNESGTVASSSTAILVSARMAPTEMVLDRSFLFVVRHNPTETILFMGQLMEP
What is the function of this protein?
Serine protease inhibitor.  Inhibits TMPRSS7.  Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU).  As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots.  As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.  Acts as a regulator of cell migration, independently of its role as protease inhibitor.  It is required for stimulation of keratinocyte migration during cutaneous injury repair.  It is involved in cellular and replicative senescence (By similarity).  Plays a role in alveolar type 2 cells senescence in the lung (By similarity).  Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis (By similarity).
What are the official names of this protein?
Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1.
What is the protein family that this protein belongs to?
Belongs to the serpin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PTCA_LACLM
Sequence: MTDKYENPTSDDYMGVVMGIIMSGGNAKGLAFQAIQQAKDGKFAEAESSLNEASEQLREAHDVQTDLLTRLAQGEKIGWNLYMVHAQDHLMNAITFKDLAVEVVGQERRLQALENK
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity).  Involved in galactose transport with PtcB and Lmg_0963 (PubMed:30123211).
What are the official names of this protein?
PTS system galactose-specific EIIA component.
Protein: NTM2G_HUMAN
Sequence: MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPSPGPTHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTLILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNAGPWPQGAHGEGSLAPSQAKARPDDSCKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAAKFLEFEAEEEMQIQKSQWMKGPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPPRPAETKVPEEIPPEVVQEYVDIMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGMTSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKRLLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHRPTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRPLFGSPSPAEKTPHPGPGLRVSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ
What are the official names of this protein?
NUT family member 2G.
What is the protein family that this protein belongs to?
Belongs to the NUT family.
Protein: SYFA_YERPY
Sequence: MPHLAELVAKAKAAVEDAQDIAALDLVRVEYLGKKGHLTLQMTSLRELPAEERPAAGAVINQAKQEVQEALNARKEKLESAVLNARLAAETIDVSLPGRRMENGGLHPVTRTIERIETFFGELGFSVESGPEIEDDYHNFDALNIPAHHPARADHDTFWFDATRLLRTQTSGVQIRTMQEQQPPIRIIVPGRVYRNDYDQTHTPMFHQMEGLIVDRDISFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEIYSGFAFGMGMERLTMLRYGVTDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGE_ECO81
Sequence: MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASCGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTALRPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYDAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
What is the function of this protein?
Catalyzes the hydrolysis of the amide bond of N(2)-acetylated L-amino acids.  Cleaves the acetyl group from N-acetyl-L-ornithine to form L-ornithine, an intermediate in L-arginine biosynthesis pathway, and a branchpoint in the synthesis of polyamines.
What are the official names of this protein?
Acetylornithine deacetylase, AO, Acetylornithinase, N-acetylornithinase, NAO.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20A family. ArgE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECE_STAEQ
Sequence: MAKKESFFKGVKSEMEKTSWPTKEELFKYTIIVVSTVIFFLVFFYALDIGINALKQLFLG
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CAPPA_FLATR
Sequence: MANRNVEKLASIDAQLRLLVPGKVSEDDKLVEYDALLLDKFLDILQDLHGEDLKEAVQQCYELSAEYEGKHDPKKLEELGSLLTSLDTGDSIVIAKAFSHMLNLANLAEELQIAYRRRIKLKSGDFADEANATTESDIEETFKRLVHKLNKSPEEVFDALKNQTVELVLTAHPTQSVRRSLLQKHGRIRNCLAQLYAKDITPDDKQELDEALHREIQAAFRTDEIRRTPPTPQDEMRAGMSYFHETIWKGVPKFLRRVDTALKNIGINERFPYNAPLIQFSSWMGGDRDGNPRVTPEVTRDVCLLARMMTSNMYFSQIEDLMIEMSMWRCNSELRVRAEELYRTARKDVKHYIEFWKRIPPNQPYRVILGDVRDKLYNTRERSRHLLVDGKSDIPDEAVYTNVEQLLEPLELCYRSLCDCGDHVIADGSLLDFLRQVSTFGLSLVKLDIRQESDRHTEVLDAITQHLGIGSYREWSEEKRQEWLLAELSGKRPLIGPDLPKTEEVKDCLDTFKVLAELPSDCFGAYIISMATSTSDVLAVELLQREYHIKHPLRVVPLFEKLADLEAAPAAMTRLFSMDWYRNRIDGKQEVMIGYSDSGKDAGRFSAAWQLYKTQEQIVKIAKEFGVKLVIFHGRGGTVGRGGGPTHLALLSQPPDTINGSLRVTVQGEVIEQSFGEEHLCFRTLQRFCAATLEHGMNPPISPRPEWRELMDQMAVVATEEYRSVVFKEPRFVEYFRLATPELEFGRMNIGSRPSKRKPSGGIESLRAIPWIFSWTQTRFHLPVWLGFGAAFKHAIQKDSKNLQMLQEMYKTWPFFRVTIDLVEMVFAKGNPGIAALNDKLLVSEDLRPFGESLRANYEETKNYLLKIAGHKDLLEGDPYLKQGIRLRDPYITTLNVCQAYTLKRIRDPNYHVTLRPHISKEYAAEPSKPADELIHLNPTSEYAPGLEDTLILTMKGIAAGMQNTG
What is the function of this protein?
Forms oxaloacetate through the carboxylation of phosphoenolpyruvate (PEP).  Catalyzes the first step of C4 photosynthesis.
What are the official names of this protein?
C4 phosphoenolpyruvate carboxylase, C4 PEPC, C4 PEPCase, ppcA, Photosynthetic PEPCase.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SM30_STRPU
Sequence: MRGFVYVLVCVLALASFSRAQLPGAGGPVLPGGGPTIGPVNPDPTRTEVCAKFWVQEGNSCYLFDSGAFLRQVAASRPVVVNNQDGLFQAAANMYCGQMHPNASLVTVNSLEENNFLYEWAVRMMIEPEPVWIGLHAGPTGQWQWYSGEPVTYTNWERMTPPIAEPGLGAMIFDADIIAQMFNNQVEITPQWVPEQAINDRHALICEYHPSGMTAAAAAPTNAPTFPPMTTAPPMAATTRGPVMFQNNPRNLVNSLTGGRFGGSLLHEIPRRQRMRPSNYRKNPYFGIQP
What is the function of this protein?
Matrix protein of the sea urchin embryo spicule.  The function of the matrix proteins is to direct crystal growth in certain orientations and inhibit growth in others.
What are the official names of this protein?
30 kDa spicule matrix protein.
Protein: MNMA_HYDS0
Sequence: MIIAVGMSGGVDSSVAAYLLKEQGHDVIGVTLRFYKEECKENARVCCSPKDVQDARIVCDMLGIPHITLDWENLFKERVIDYFIKSYKTGLTPNPCAICNKDVKTAFLGFYLKQTADIDFLATGHYVIKEEGKIKRAKEKDQSYFMALVPKQSLDYLMFPVGYMTKQEIRDIAKKINLPVANKIESQDVCFLKGMDLEDYLSQFIDMTQGDIVHIATQKTLGKHKGIHRYTIGQRHGLGVSYHKPLYVVEKDIEKNILYVGEKEYLLKDAITLKDYNKLEDFEKDNMYIQIRYNSKPIPIKHIEENKDNVIIFLKEPATQVAKGQVGAIYFGDILLGGGIIS
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEBF_SALPC
Sequence: MNKRGALLSLLLLSASVSAFAASTESKSVKFPQCEGLDAAGIAASVKRDYQQNRIVRWADDQKKVGQADPVAWVNVQDVVGQNDKWTVPLTVRGKSADIHYQVIVDCKAGKAEYKPR
What are the official names of this protein?
Protein YebF.
What is the protein family that this protein belongs to?
Belongs to the YebF family.
What are the subcellular locations of this protein?
Secreted.
Protein: TAT_HV1SC
Sequence: MDPVDPRLEPWKHPGSQPKAACTSCYCKKCCFHCQVCFTTKGLGISYGRKKRRQRRRAPQDSQTHQVSLPKQPASQARGDPTGPKESKKKVERETETDPVD
What is the function of this protein?
Extracellular circulating Tat can be endocytosed by surrounding uninfected cells via the binding to several surface receptors such as CD26, CXCR4, heparan sulfate proteoglycans (HSPG) or LDLR.  Neurons are rarely infected, but they internalize Tat via their LDLR.  Through its interaction with nuclear HATs, Tat is potentially able to control the acetylation-dependent cellular gene expression.  Modulates the expression of many cellular genes involved in cell survival, proliferation or in coding for cytokines or cytokine receptors.  Tat plays a role in T-cell and neurons apoptosis.  Tat induced neurotoxicity and apoptosis probably contribute to neuroAIDS.  Circulating Tat also acts as a chemokine-like and/or growth factor-like molecule that binds to specific receptors on the surface of the cells, affecting many cellular pathways.  In the vascular system, Tat binds to ITGAV/ITGB3 and ITGA5/ITGB1 integrins dimers at the surface of endothelial cells and competes with bFGF for heparin-binding sites, leading to an excess of soluble bFGF.
What are the official names of this protein?
Protein Tat, Transactivating regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the lentiviruses Tat family.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host cytoplasm. Secreted. Note=Probably localizes to both nuclear and nucleolar compartments. Nuclear localization is mediated through the interaction of the nuclear localization signal with importin KPNB1. Secretion occurs through a Golgi-independent pathway. Tat is released from infected cells to the extracellular space where it remains associated to the cell membrane, or is secreted into the cerebrospinal fluid and sera. Extracellular Tat can be endocytosed by surrounding uninfected cells via binding to several receptors depending on the cell type.
Protein: MDH2_RHOPB
Sequence: MSRKKIVLAGAGQIGGTLAHLAMLHRLGDVTLLDVNANPPKGKALDLSHAAAVEGCDAVLTGTADQADIAGADVVIVTAGVPRRPGVDRDALLAINLPVMESIGTAIGRYCPDAFVICITNPLDAMVWALRRFSGLPPARVVGMGGVLDSARLRSFLAEALGVSVTEVQAMTLGGHGDDMVPLVRQATVGGVPLPALVKMGWITQQAIDDIVQRTRTGGAEVVNLLWTSSAYYAPASAAIAMATSYLGDQKRVFAASAALSGQYGVDGLHVGVPVMIGAGGIEKIIELEFDDEEQRQFTRSVAAVAALVEDCKRLHRGLA
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.