PharMolix/UniProtQA huggingface dataset:
Protein: RAGP2_ARATH
Sequence: MADILDSRPHAFSIKLWPPSLPTRKALIERITNNFSSKTIFTEKYGSLTKDQATENAKRIEDIAFSTANQQFEREPDGDGGSAVQLYAKECSKLILEVLKKGPVAKVAARELISEDSVSPRETFFDISKGKRAFIEAEEAEELLKPLKEPGNAYTKICFSNRSFGLGAARVAEPILASLKDQLKEVDLSDFVAGRPELEALEVMNIFSDALQGSILSSLNLSDNALGEKGVRAFGALLKSLSSLEELYLMNDGISKEAAQAVSELIPSTENLRVLHFHNNMTGDEGALAIAEVVKRSPLLENFRCSSTRVGSKGGIALSEALEHCTHMEKLDLRDNMFGTEAGVSLSKTLSSFKHMTELYLSYLNLEDEGAIAIVNALKESASPIEVLEMAGNDITVEAASAIAACVAAKQDLNKLNLSENELKDEGCVQIANCIEEGHSKLQYIDMSTNYIRRAGARALAHVVVKKEAFKLLNIDGNIISEEGIEELKEIFKKSPELLGALDENDPDGEEDDDDEEDEEDEENEGNGNGELESKLKNLEVNQED
What is the function of this protein?
GTPase activator for the nuclear Ras-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state.
What are the official names of this protein?
RAN GTPase-activating protein 2, AtRanGAP2, RanGAP2.
What is the protein family that this protein belongs to?
Belongs to the RNA1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, phragmoplast. Note=Localized in patchy areas at the nuclear envelope of interphase cells. During mitosis, associates with mitotic spindles at the anaphase. Associated to the microtubular phragmoplast and the surface of the daughter nuclei at the telophase.
Protein: SPIKE_CVM4
Sequence: MLFVFILLLPSCLGYIGDFRCIQTVNYNGNNASAPSISTEAVDVSKGLGTYYVLDRVYLNATLLLTGYYPVDGSNYRNLALTGTNTLSLTWFKPPFLSEFNDGIFAKVQNLKTNTPTGATSYFPTIVIGSLFGNTSYTVVLEPYNNIIMASVCTYTICQLPYTPCKPNTNGNRVIGFWHTDVKPPICLLKRNFTFNVNAPWLYFHFYQQGGTFYAYYADKPSATTFLFSVYIGDILTQYFVLPFICTPTAGSTLLPLYWVTPLLKRQYLFNFNEKGVITSAVDCASSYISEIKCKTQSLLPSTGVYDLSGYTVQPVGVVYRRVPNLPDCKIEEWLTAKSVPSPLNWERRTFQNCNFNLSSLLRYVQAESLSCNNIDASKVYGMCFGSVSVDKFAIPRSRQIDLQIGNSGFLQTANYKIDTAATSCQLYYSLPKNNVTINNYNPSSWNRRYGFNDAGVFGKSKHDVAYAQQCFTVRPSYCPCAQPDIVSACTSQTKPMSAYCPTGTIHRECSLWNGPHLRSARVGSGTYTCECTCKPNPFDTYDLRCGQIKTIVNVGDHCEGLGVLEDKCGNSDPHKGCSCANDSFIGWSHDTCLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVATGVCVRYDLYGITGQGVFKEVKADYYNSWQALLYDVNGNLNGFRDLTTNKTYTIRSCYSGRVSAAYHKEAPEPALLYRNINCSYVFTNNISREENPLNYFDSYLGCVVNADNRTDEALPNCDLRMGAGLCVDYSKSRRARRSVSTGYRLTTFEPYMPMLVNDSVQSVGGLYEMQIPTNFTIGHHEEFIQIRAPKVTIDCAAFVCGDNAACRQQLVEYGSFCDNVNAILNEVNNLLDNMQLQVASALMQGVTISSRLPDGISGPIDDINFSPLLGCIGSTCAEDGNGPSAIRGRSAIEDLLFDKVKLSDVGFVEAYNNCTGGQEVRDLLCVQSFNGIKVLPPVLSESQISGYTAGATAAAMFPPWTAAAGVPFSLNVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQEGFDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILTRLDAVEAKAQIDRLINGRLTALNAYISKQLSDSTLIKFSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAPYGLCFIHFSYVPTSFKTANVSPGLCISGDRGLAPKAGYFVQDNGEWKFTGSNYYYPEPITDKNSVVMISCAVNYTKAPEVFLNNSIPNLPDFKEELDKWFKNQTSIAPDLSLDFEKLNVTFLDLTYEMNRIQDAIKKLNESYINLKEVGTYEMYVKWPWYVWLLIGLAGVAVCVLLFFICCCTGCGSCCFRKCGSCCDEYGGHQDSIVIHNISAHED
What is the function of this protein?
Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis.
What are the official names of this protein?
Spike glycoprotein, S glycoprotein, E2, Peplomer protein.
What is the protein family that this protein belongs to?
Belongs to the betacoronaviruses spike protein family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Note=Accumulates in the endoplasmic reticulum-Golgi intermediate compartment, where it participates in virus particle assembly. Some S oligomers are transported to the host plasma membrane, where they may mediate cell- cell fusion.
Protein: NLHAP_HALAA
Sequence: MFRYLSKRQWILLLLGILFVVAGYFILPVSVPLIIALITALFLNPAVRWMQFRFRLNRKMAVTIVFLLFVIMIGLLGTYAVTRAVTQLVELADNAPSYINQINNVLINWQNNMNSFTQNMPSEFVDKVSVELQNTIDTTTQTLSQKLQLSNIAAFAAKIPEYLISFLVYLIALFLFMLELPRLKDKMHGNFTESTSEKVKFMNARLSYVVFGFLKAQFLVSIVIFVVCLIGLFWITPEVAIVMSLIIWIVDFVPIIGSIVILGPWALYMLIVGDIAMGGQLAMLAIILLAIRRTVEPKVMGRHIGLSPLATLIAMYIGLQLIGLMGFILGPLLVIAFNSAKEAGIIRWNFKL
What is the function of this protein?
Catalyzes the pH-dependent efflux of sodium and lithium in exchange for external protons.
What are the official names of this protein?
Sodium-lithium/proton antiporter, Na(+) (Li(+))/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SURE_NATTJ
Sequence: MKVLLTNDDGIYAPGIFAMAKEIASRDEFEAVVVAPDREQSATGHAITVHKPLRVNNVKKLGEKLEIPFYSVNGTPSDCVKLAVESVMDEKPDLVISGINRGANLGTDVLYSGTVSGAMEAAILNIKSIAVSLVDYDYEDYSTAASYTAYIANIIKDNPEEFENGTLLNVNVPAVEANQLKGVKITRQGFRQYENIFEKRFDPRGKAYYWMAGKVIEDTSDIKTDVASVKENYVSVTPIKYDLTDYNLYNSLSNWEFDD
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
5'-nucleotidase SurE, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MED4_CRYNJ
Sequence: MAHTTPRSHPPPHSLLQNLTTQSLLLSHLFTLIASPPNPNTSTQTQLNQVYSALQLSTLDLSGLVKEVGHHQEAYRRLVEKKNEVAGLEMRVRGLVKRLEEGRKELEGMIDQGERSLEDIEKSEREPVPAKTLMAHAQSLSKHSSAPVSSLLAPVDKAQYAPWPTEMSMRMGLLFQLEGSMSGMGERGVVGEEQKAPQKVEERREHVEHEESDRRYDPNAVFQLDLNSDESDED
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 4, Mediator complex subunit 4.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXH_CUPNH
Sequence: MTQLADLRRSYVLGSLSETDVAPDPMSQFKRWFDEAVTAKLPEPNAMTLATVDADGQPSARIVLLKGIDDRGFTFFTNYESRKGLDLAANPRAALLFHWVQLERQVRVEGRVEKVSDDESDAYFATRPLGSRVGAWASAQSREVPGRDVLEQREQEYRSKFGENPPRPPHWGGYRLVPTALEFWQGRPSRLHDRIAFRLQPGGDWQIVRLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: TIG_WOLSU
Sequence: MNLQTQKINSANATAKGTLEKALLEEKLDKLSKDAAKNLKVDGFRKGKVPAGVIKARYGEKLQEDAEREALQELLDAALKDLGAEPSQLIGDPRITEYNKHDNGIDVEVKIGLAPEITLQESLTYVPGFELPSVSEEEINTRLMELAKAKAPLAPAPEGKALENGDFAKIDFEGFLGEEAFEGGKAEDYMLQIGSKSFIPGFEDQLIGMKAGEKRDIQVKFPENYGSEKLAGQEATFKIALKEIQVKAPQEPSDEFAKSVLPEEPEANLNLLKEKIKEQIATEKKVELYNSELKTKLVDNLVEALAFDLPELVVEQEIDLVFRNTLSSLSKEEIEALRNDQEAVKAKREEHRESATRSVKVTFIVDALAKKEGIAVQDNELIQTIYYESMAMGQDPKAMLEYYKNNNLLPAVRMAMLEDKLLTHLLDQKIKG
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: PHAX_MOUSE
Sequence: MALEAGDMEEGQLSDSDSDMTVVPSDRPLQMAKVLGGGSAACAPVSHYRTVKHVDSSEESLDSDDDCSLWKRKRQKCHNTPPKPEPFPFGPSGQKTALNGGKKVNNIWGAVLQEQNQDAVATELGILGMEGSIDRSRQSETYNYLLAKKLAKKESQEYTKELDKDLDEYMHGDKKPGSKEDENGQGHLKRKRPVRDRLGNRVEMNYKGRYEITEEDAPEKVADEIAFRLQEPKKDLIARVVRILGNKKAIELLMETAEVEQNGGLFIMNGSRRRTPGGVFLNLLKNTPSISEEQIKDIFYVENQKEYENKKAARKRRTQLLGKKMKQAIKSLNFQEDDDTSRETFASDTNEALASLDEAQEGPGETKLDAEEAIEVDHPQDLDIF
What is the function of this protein?
A phosphoprotein adapter involved in the XPO1-mediated U snRNA export from the nucleus.  Bridge components required for U snRNA export, the cap binding complex (CBC)-bound snRNA on the one hand and the GTPase Ran in its active GTP-bound form together with the export receptor XPO1 on the other.  Its phosphorylation in the nucleus is required for U snRNA export complex assembly and export, while its dephosphorylation in the cytoplasm causes export complex disassembly.  It is recycled back to the nucleus via the importin alpha/beta heterodimeric import receptor.  The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.  Its compartmentalized phosphorylation cycle may also contribute to the directionality of export.  Binds strongly to m7G-capped U1 and U5 small nuclear RNAs (snRNAs) in a sequence-unspecific manner and phosphorylation-independent manner.  Also plays a role in the biogenesis of U3 small nucleolar RNA (snoRNA).  Involved in the U3 snoRNA transport from nucleoplasm to Cajal bodies.  Binds strongly to m7G-capped U3, U8 and U13 precursor snoRNAs and weakly to trimethylated (TMG)-capped U3, U8 and U13 snoRNAs.  Binds also to telomerase RNA (By similarity).
What are the official names of this protein?
Phosphorylated adapter RNA export protein, RNA U small nuclear RNA export adapter protein.
What is the protein family that this protein belongs to?
Belongs to the PHAX family.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleoplasm. Nucleus, Cajal body. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm. Shuttles between the nucleoplasm and Cajal bodies.
Protein: Y1189_GLUDA
Sequence: MTDSSHDGVPAPRRILLVTGLSGAGKSSILRILEDLGYEVIDNPPLGMMDEIVTRAEQPVAIGVDSRTRGFDAAAVLAALGRLRVNPDLQAELIYATAEESVLLRRYTATRRRHPLAMRGTVKEGIEAEIELTARLRAAADMVIDTSDLPPPELRQVVEMRFAPRHDRMAEGLTVALMSFAFPAGLPREADMVFDARFLRNPYYDPDLSVRNGLDQAVADYVASDPDYPRFLDQIDGMLGLVLPRFVREGKKYATIAIGCSGGRHRSVTLVEALARRLAAKNLAEPGGTCDSPGKPAHIEKGAAPTDVQSGGADAQGAWPIIVMHRELARQGRSSWRWASRPREHAADVVEGQYSS
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein GDI1189/Gdia_1902.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: RL30_THEAC
Sequence: MLAVIRIRGRTGIKEDIADTAHLMRLNRINHLVLLNENEVVKGMLQKVKDYVTWGEIDLDTLELLLKNRLLFRGRKHLTEEELKEKTGFTSYRDLAQALIDGKIKPSEIADAVPVIRLNPPKGGYEAIRKSYRSGGSSGYRGSDINQLIRRMIISGVDLNGKREN
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: ALGG_AZOVI
Sequence: MNVQRKLASTQLKPVLLGVLLATSAWSQAAPPEQARQSAPPTLSSKQYSVTSASIEALKLDPPKLPDLSGYTHAAVEAKIRRKPGGRIAAAMLQQTALKDFTGGSGRLREWIVRQGGMPHAIFIEGGYVELGQLARQLPANQFAETTPGVYVARVPIVVAPGATLHIGKNVKELRLSEERGAFLVNDGKLFITDTKLVGWSEKNNAPSAYRGPESFWAFLVSWGGTETYISRRPVASLGYNTSKAYGVSITQYTPEMHKRLKRPRPTGWLIDSVFEDIYYGFYCYEADDVVLKGNTYRDNIIYGIDPHDRSERLVIAENHVYGTKKKHGIIVSREVNNSWIINNRTHDNKLSGIVLDRNSEHNLVAYNEVYQNHSDGITLYESSNNLIWGNRLINNARHGIRMRNSVNIRIYENLSVVNQLTGIYGHIKDLSSTDRDFKLDPFDTKVSMIVVGGQLTGNGSSPISVDSPLSLELYRVEMLAPTKSSGLTFTGILEDKQEEILDLLVRRQKAVLIDPVVDLAQAEL
What is the function of this protein?
Catalyzes the epimerization of beta-D-mannuronate to alpha-L-guluronate during the synthesis of the linear polysaccharide alginate (PubMed:8830682).  In addition, is part of a periplasmic protein complex that protects alginate from degradation by AlgL by channeling the newly formed alginate polymer through a scaffold that transfers the alginate polymer through the periplasmic space to the outer membrane secretin AlgE (By similarity).
What are the official names of this protein?
Mannuronan C5-epimerase AlgG, Poly(beta-D-mannuronate) C5 epimerase.
What is the protein family that this protein belongs to?
Belongs to the D-mannuronate C5-epimerase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: LUXS_PECAS
Sequence: MPLLDSFTVDHTRMAAPAVRVAKTMKTPHGDNITVFDLRFCRPNIEVMPERGIHTLEHLFAGFMRDHLNGDGVEIIDISPMGCRTGFYMSLIGTPDEQRVAESWKAAMSDVLKVTDQRKIPELNEYQCGTYDMHSLKEAQEIAQHIVDHDIGINQNDDLALPKDKLAELHI
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: NAGB_SERP5
Sequence: MRLIPLKDTAQVGKWAARHIVQRINAFKPTAERPFVLGLPTGGTPLEAYKHLIAMHKAGEVSFKHVVTFNMDEYVGLPQEHPESYHTFMYRNFFDHVDIPSENINLLNGNAPDVDAECRQYEAKIKSYGKINLFMGGVGIDGHIAFNEPASSLASRTRIKTLTEDTRIANSRFFGGDVSLVPKFALTVGVGTLLDAEEVMILVTGHAKAQALEAAVEGNINHMWTISCLQLHAKAVVVCDEPSTMELKVKTVKYFRELEAESVKSL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: CSRA_EXISA
Sequence: MLVLKRKQGEAIHIGDDVTLTVLAIEGDQVKLGIDAPRHIDIHRHEVYIQMQEENESARNSANLMKQMIQKQSEA
What is the function of this protein?
A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation.  Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
What are the official names of this protein?
Translational regulator CsrA.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: E13D_HORVU
Sequence: IGVCYGIIANNLPPRREVVQLYRSKGITNMRIYSVQPQAIRALHGSGIRLMLGTTNNDVAVLAGSLSAATSWVHANVKPYHSAGVTIRYIAVGNEITGGAAQSILAAMRNLNKALAAARLGGIKVSTAVRFDVITNSFPPSSAVFAQPYMVDIARHLASTNAPLLANVYPYFAYSGNPRDIKLNYATFQPGATPVRDAGNGLIYTNLFNAMVDAMYAALEKAGAPSVRVVVSESGWPSAGGFAATPENARAYNQGLIDHVAHGTPKKPGHMEAYVFAMFNENQKPGLETERHFGLFYPNKRPVYHINFAGGRLAPVNHTNSHGFGGH
What is the function of this protein?
May provide a degree of protection against microbial invasion of germinated barley grain through its ability to degrade fungal cell wall polysaccharides.
What are the official names of this protein?
Glucan endo-1,3-beta-glucosidase GIV, (1->3)-beta-glucan endohydrolase GIV, (1->3)-beta-glucanase isoenzyme GIV, Beta-1,3-endoglucanase GIV.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 17 family.
What are the subcellular locations of this protein?
Vacuole.
Protein: S15A2_RAT
Sequence: MNPFQKNESKETLFSPVSTEEMLPRPPSPPKKSPPKIFGSSYPVSIAFIVVNEFCERFSYYGMKAVLTLYFLYFLHWNEDTSTSVYHAFSSLCYFTPILGAAIADSWLGKFKTIIYLSLVYVLGHVFKSLGAIPILGGKMLHTILSLVGLSLIALGTGGIKPCVAAFGGDQFEEEHAEARTRYFSVFYLAINAGSLISTFITPMLRGDVKCFGQDCYALAFGVPGLLMVLALVVFAMGSKMYRKPPPEGNIVAQVIKCIWFALCNRFRNRSGDLPKRQHWLDWAAEKYPKHLIADVKALTRVLFLYIPLPMFWALLDQQGSRWTLQANKMNGDLGFFVLQPDQMQVLNPFLVLIFIPLFDLVIYRLISKCRINFSSLRKMAVGMILACLAFAVAALVETKINGMIHPQPASQEIFLQVLNLADGDVKVTVLGSRNNSLLVESVSSFQNTTHYSKLHLEAKSQDLHFHLKYNSLSVHNDHSVEEKNCYQLLIHQDGESISSMLVKDTGIKPANGMAAIRFINTLHKDLNISLDTDAPLSVGKDYGVSAYRTVLRGKYPAVHCETEDKVFSLDLGQLDFGTTYLFVITNITSQGLQAWKAEDIPVNKLSIAWQLPQYVLVTAAEVMFSVTGLEFSYSQAPSSMKSVLQAAWLLTVAVGNIIVLVVAQFSGLAQWAEFVLFSCLLLVVCLIFSVMAYYYVPLKSEDTREATDKQIPAVQGNMINLETKNTRL
What is the function of this protein?
Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides (PubMed:8639691, PubMed:26320580).  Transports the dipeptide-like aminopeptidase inhibitor bestatin (PubMed:8639691).  Can also transport the aminocephalosporin antibiotic cefadroxil (By similarity).  Also able to transport carnosine (By similarity).  Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs).  Probably acts by mediating transport of bacterial peptidoglycans across the plasma membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).
What are the official names of this protein?
Solute carrier family 15 member 2, Kidney H(+)/peptide cotransporter, Oligopeptide transporter, kidney isoform, Peptide transporter 2.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MTGA_PASMU
Sequence: MSKLKKTKHPFPCFSIWQQFKRKLYRTFALFLVLFLSSVVLFRFVPVPFSAYMLQQKIGYLFEGNLSSTIHYQWVPLEQISQSMQLAVIASEDQRFATHYGFDWDAIQSALQHNQRGKRIRGGSTISQQTAKNLYLWHGQSWLRKAIEMPTTLVLETLWSKKRILEVYLNIAEFGPNIFGVEAASQHYFRKPAKQLSNAEAALLAAVLPNPIIFKVNKPSAYVKKRQQHIQRQMGLLGKQHLSQLD
What is the function of this protein?
Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.
What are the official names of this protein?
Biosynthetic peptidoglycan transglycosylase, Glycan polymerase, Peptidoglycan glycosyltransferase MtgA, PGT.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 51 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: CYOA_PSEPU
Sequence: MSKKRYPRLFGILPFLGMLLLSGCNWTLLDPKGQVGIEQKNLILIATGLMLLVVIPVIIMTVVFAWKYRASNKAATYTPDWSHSTKIEAAVWIIPILIIIALGYFTYHSTHKLDPYRPLDSDVKPVQIDVVALDWKWLFIYPEQGIATVNKIVFPANTPVNFRVTSDAVMNSFFIPGLGGQIYAMAGMTTKLHLIANENGEFDGISANYSGAGFTGMKFKATATSQEDFDKWVAEVKQSPKKLDKAEYEALAKPSENNPVALYSEASPDQFQLIVDKYEGMNRGRPSHEEAGSKDLATTKGVESSMQPAAGAEE
What is the function of this protein?
Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E. coli that predominates when cells are grown at high aeration.  Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron (By similarity).
What are the official names of this protein?
Cytochrome bo(3) ubiquinol oxidase subunit 2, Cytochrome o ubiquinol oxidase subunit 2, Cytochrome o subunit 2, Oxidase bo(3) subunit 2, Ubiquinol oxidase polypeptide II, Ubiquinol oxidase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: GLPR_HALVD
Sequence: MLPAERKRRIVELVSDSDGRSVESLSDHLGYSKATIRRDLRELEDRGLIERSHGGAVPVTSVGREQTYGQKEVQNLEGKRAIADRAVEELAEGQVVFFDAGTTTMEVARKVPKDGTILGVTNSPRLAIELNEEDNEVKLTGGTLRRRTKALVGPTAESFMERTNFDLLFLGTNALDVESGLTTPNEDEARMKELMVEKAAKVVLVADLSKLGRRSFVQFASLEEIDLFITDGTLDADSREEIESAGVTVVDGVAR
What is the function of this protein?
Transcriptional repressor of genes encoding both fructose and glucose metabolic enzymes such as phosphofructokinase (PFK) or 2-keto-3-deoxy-D-gluconate kinase (KDGK) during growth on glycerol.  Required for the glycerol-mediated repression of pfkB-specific transcripts, but not needed for the high-levels of the pfkB-specific transcript present when cells are grown on fructose.
What are the official names of this protein?
HTH-type transcriptional regulator GlpR.
Protein: ACPS_ANASK
Sequence: MILGLGLDVVEVARIQRILAGPPARAERFLARVFAPSERAYCDARQDRATRYAARFAAKEAAVKALGTPEGVRWLDLVVERGSGAPSLALDGLAADAARRLGVARVHLTLTHDAGVAVAAVILEGTGP
What is the function of this protein?
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.
What are the official names of this protein?
Holo-[acyl-carrier-protein] synthase, Holo-ACP synthase, 4'-phosphopantetheinyl transferase AcpS.
What is the protein family that this protein belongs to?
Belongs to the P-Pant transferase superfamily. AcpS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBA_PSEPK
Sequence: MPVVFVAASKLPTPFATFTMHGFLDEATGREHVVLSLGDIADGQPVLGRLHSECLTGDALFSQRCDCGSQLEAALQAIAREGRGVLLYLRQEGRGIGLLNKIRAYELQDGGADTVEANERLGFAADQRDYAICLPMLEHLGVKSLRLMTNNPRKVKALTDMNIVVAERVPLHTGHNPHNRYYLATKAGKLGHMLGNEHQGEVPQA
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
GTP cyclohydrolase-2, GTP cyclohydrolase II.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase II family.
Protein: Y928_AQUAE
Sequence: MEFVVKETDGDTLYKLVLGLVVPRPIGWVSTISKDGILNIAPFSFFNVVNDEPPVLMISVSNRDDNTLKDTVKNVLDTKEFVVNMVSEEVFEKMLITGEEFPPEVNEFEKAGLTPETSKFVKAPRIKEAKVSFECKLYKYVPVYDMHVIFGEALLIKVEDTILDENLNVNYEKYRPIGRLGGKYYVKAFGECKLKV
What are the official names of this protein?
Uncharacterized protein aq_928.
What is the protein family that this protein belongs to?
Belongs to the flavoredoxin family.
Protein: SENP7_MOUSE
Sequence: MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLSKLRGSECWWTRSLRNKVICLDHKKPKAARGCPPKGLPKRHLRVMLTNVLWTDLGREFRKTLPRKDANLCAPSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERTPRVILTDIRQTELGRKYLKIPPVTEASLSDTANLKSEQLSSSSDGSLESCQSVNHHKSFLSESGPKPSRTGDVPAKEAACGGQKQGDDGGVTPEMAAPHPKDFNTGNKGCDYLEEGTSNKNTSYSYSEMDHTPVSRKRKKRGRSNFHDSHNSKTSLDKPTEHTKEEENDSSVSRKLEESGEDSHQDPAPPEGLAPESLESEATNLRSFAAGQEPDASAASGRASSPNKSLESSASSEVSENSSVAVKGEALTLKEASPPGGSSEESQLLISAEPIVVSSDEEGPVEHKNSVILKLQPPHEIMSENQGTSDPQLSELTLGACESVQVTSELFPYNPDVENISCIKSNSEMDLKLDFIFTCVYIGKIKGTPKGCVTFTKKYIKIPFQVSTNEISLTVDTARLKRFGLWESKDEDHSKRSHAILFLWLSSDYLQDIQTQLENPMLSQQSKANEFIFLELNSSISQREELKLKDIMMEISTKNGNLHLSCPLPWVQALPLFQDLSPQEISFLHYYYASASALPTAAGADMKKKSVSQPSNSDTIKPTYTFLHKQSSGCYSLSITSSPEEEWQEVRNTGPVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDCPQTVSQQFQGQQSQHDHKMTDNDPHTTSTVSTSAEDSQSTEVNMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGGSC
What is the function of this protein?
Protease that acts as a positive regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS (PubMed:28095500).  Desumoylation of CGAS promotes DNA-binding activity of CGAS, subsequent oligomerization and activation (PubMed:28095500).  Deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1 (By similarity).  Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains (By similarity).  Has very low efficiency in processing full-length SUMO proteins to their mature forms (By similarity).
What are the official names of this protein?
Sentrin-specific protease 7, SUMO-1-specific protease 2, Sentrin/SUMO-specific protease SENP7.
What is the protein family that this protein belongs to?
Belongs to the peptidase C48 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GDT14_ORYSI
Sequence: MARRVSTTRLLLLLLLVAAAAAAAAGDQEDPRGGGDNGTARLDRRTKMFLHAARASDGGATGMEKAGLGLFDAFFASLSMILVSEIGDETFIIAALMAMRHPKSTVLSGALSALVVMTILSTGLGRIVPNLISRKHTNSAATVLYAFFGLRLLYIAWRSDSKASQKKEIEEVEEKLEAGQGKSTFRRIFSRFCTPIFLESFVLTFLAEWGDRSQIATIALATHKNAVGVAVGATLGHTICTSFAVVGGSMLASKISQGTVATIGGLLFLGFSLSSYFYPPL
What are the official names of this protein?
GDT1-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the GDT1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.