PharMolix/UniProtQA huggingface dataset:
Protein: TEG3_EHV1B
Sequence: MSFSARSRRQRLQLEEAYQREMIFKMHTLDLVREGVNKRSPAFVRAFTSAKEASLDLDRYMQAHSRVGRVEQNARALAQRVEAQAAVGEILDRHRRFLHPDFIDNFDSREDSIVEREERLGDVLSDINCDGGGGEVGDPQEWLGHEDEALLMRWMLEEAPRVSTRIAADPHSPRSTCPAPRKAPEDARCGARKPGEVNNYTPSAQPRSQETTVDHLASPDEGTRLGDRTRDLEHHSTAPMRTHPNVLASERRRLGVVHQREKSSESQESATRSKAIVGQEDQKWLGGIPPLSDEELQVDMGIPTMNGPIYPDYHRTA
What is the function of this protein?
Contributes to the nuclear transport of the viral transcriptional activator VP16 during the early phase of infection.  Therefore, participates indirectly in the regulation of the immediate-early gene expression.  Additionally, seems to be important for efficient nuclear targeting of capsids (By similarity).
What are the official names of this protein?
Tegument protein UL14 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL14 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: GPMI_HALH5
Sequence: MSKKPVALIILDGFAMRDEAKGNAVAQANKPNFDRYWNQYPHALLKADGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNLSIREGEFFENETFLNAMNHVKEKGSSLHIYGLVSDGGIHSHINHLYALLELAKREQVERVYIHGFLDGRDVGPTSAESYLVDLEAKMKELGVGELATLHGRYYAMDRDKRWDRVEKSYRAMVYGEGPAYSSALDVIKDSYENSIHDEFVIPSVITNEDGSPVATIEDDDAIIFFNFRPDRAIQMSQVFTNKDFRGFDRGEKLPQNVYYVCLTHFSETVQGDVAFKPTNLDNTLGEVLAQQNYKQLRIAETEKYPHVTFFFSGGREEPFPGEERILIDSPKVATYDLKPEMSAYEVTDALLNEIEADKHDVIILNFANPDMVGHSGMLEPTIKAVEAVDECLGKVVDAILAKGGAAVITADHGNADEVVTLEGKPMTAHTTNKVPVIVTEEGLNLREDGILADLSPTVLDLLGGKQPAEMTGKTLIK
What is the function of this protein?
Essential for rapid growth and for sporulation.  Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: COX6_NEUCR
Sequence: MASFFRTAVRGPSAGLFRAVARPQPIAARVSLFSTSSRFRSEHHEETFEEFTARYEKEFDAVQDVFELQRNLNNAFAYDLVPSPSVLAAALKAARRVNDFPTAVRVFEGIKAKVENKGQYEQYLAELKPLREELGITLKEDLYPEEAN
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of Cox2 and heme A of Cox1 to the active site in Cox1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 6, mitochondrial, Cytochrome c oxidase polypeptide VI, Cytochrome c oxidase subunit Cox6.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 5A family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: G6PI1_STRCO
Sequence: MSDTPKLNQRPEWTALADHAKGTLPHPDLRELFAQDPGRAERYVVRVGDLRIDYSKHLVTDETLALLQELAAATGVSGLRDAMFRGERINITEDRAVLHTALRAPRDAVIEVDGENVVPQVHAVLDKMAGFADRVRSGEWTGHTGRRIRNVVNIGIGGSDLGPAMAYEALRAFTDRSLTLRFVSNVDGADLHEAVRDLDPAETLFIIASKTFTTIETITNATSARSWLLDGLGGDEKAVAKHFVALSTNAEKVADFGIDTANMFEFWDWVGGRYSFDSAIGLSLMIAIGPDRFREMLDGFRIVDEHFRNAEAPANAPLLLGLLGVWYGDFLGAQSHAVLPYSHYLSKFTAYLQQLDMESNGKSVDREGNPVQWQTGPVVWGTPGTNGQHAYYQLIHQGTKLIPADFIGFARPVDELSEELKAQHDLLMANFFAQTQALAFGKTPDEVRAEGVPEELVPHKTFRGNHPTTTVLAAELTPSVLGQLIALYEHKVFVQGAIWNIDSFDQWGVELGKVLAKRVEPALTEGADVPGLDPSTAALVAAYRELKEVH
What is the function of this protein?
Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
What are the official names of this protein?
Glucose-6-phosphate isomerase 1, GPI 1, Phosphoglucose isomerase 1, PGI 1, Phosphohexose isomerase 1, PHI 1.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAX_CHICK
Sequence: MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQANYPAADSSLYTNPKGSTISAFDGGSDSSSDSEPDEPQSRKKLRMEAS
What is the function of this protein?
Transcription regulator.  Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'.  The MYC-MAX complex is a transcriptional activator, whereas the MAD-MAX complex is a repressor (By similarity).
What are the official names of this protein?
Protein max, Myc-associated factor X.
What is the protein family that this protein belongs to?
Belongs to the MAX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAA_SHIBS
Sequence: MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: MC3R_MOUSE
Sequence: MNSSCCLSSVSPMLPNLSEHPAAPPASNRSGSGFCEQVFIKPEVFLALGIVSLMENILVILAVVRNGNLHSPMYFFLCSLAAADMLVSLSNSLETIMIAVINSDSLTLEDQFIQHMDNIFDSMICISLVASICNLLAIAIDRYVTIFYALRYHSIMTVRKALTLIGVIWVCCGICGVMFIIYSESKMVIVCLITMFFAMVLLMGTLYIHMFLFARLHVQRIAVLPPAGVVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFKEILCGCNSMNLG
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  This receptor is mediated by G proteins which activate adenylate cyclase.  Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain (PubMed:19036988).
What are the official names of this protein?
Melanocortin receptor 3, MC3-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CCHL_CANAW
Sequence: MGWFWADKPSQDTVKATSSFTTPSACPIDHSKLASSSPTCPVKLNNDNDEVLNPLNNMPMAISSERAPGQRIKLSTERTISTIPRGESEDQGLWEYPSPQQMLNAMLSKGKGDGVPEDAVESMVEVHNFLNEGAWQQILTWEDQYTQQTKVEPRLKKFTGRPHDLSPKARMYLWLGQLFPETFNTIPPFDRHDWTVLRSCGRNQGWKEVRYVIDYYGAPDDEETGMPAFMLDTRPALDNLTNARDRFTHWAYPLWKKAMGEVRD
What is the function of this protein?
Lyase that probably catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
What are the official names of this protein?
Holocytochrome-c synthase, Cytochrome c heme lyase, CCHL.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-type heme lyase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: PFDB_THEGJ
Sequence: MQNIPPQVQSMLAQLESYQQQLQLLVQQKQKVQLELNEAKKALEEIEKLPDDAVIYKTVGTLIVKTEKAKAVEELKEKVETLEVRLNALERQEKKLNEKLKELTAKIQASLKPPVAG
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit beta, GimC subunit beta.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_SOLUE
Sequence: MPILQVIVLAVVQGLTEFLPISSTAHLYLTSWLLGWQIEGLDFDIALHIGTLLAVLIFFARDWLQIIAQGFGIRREGDRELNHNHMLLWLLLIGTVPVGIAGLLFNKQAEGAWRNPFVMGFMLIVVGVLMWIAENAGRQQRDLSSLDLADTLAIGTAQALAVVPGTSRSGVTITAGLFRSLTRESAARFSFLLSTPAIGAAAAKAIWDMHKKGGGLHGMLHADFLVGVAVSAITGCIVIAWFLHYLRRNGLRPFVYYRILFGIIVLALAFIRRPA
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TRYA_DROER
Sequence: MLKIVILLSAVVCALGGTVPEGLLPQLDGRIVGGSATTISSFPWQISLQRSGSHSCGGSVYSANIIVTAAHCLQSVSASSLQVRAGSTYWSSGGVVAKVAAFRNHEGYNANTMVNDIAVIRLSSSLSFSSSIKAIALATYNPANGAAAAVSGWGTQSSGSNSIPSQLQYVNVNIVSQSKCASSAYGYGSEIRNTMICAAASGKDACQGDSGGPLVSGGVLVGVVSWGYGCAYSNYPGVYADVAVLRSWVISTANSI
What are the official names of this protein?
Trypsin alpha.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: RHAA_PECCP
Sequence: MSTPIETAWQLAKARYASLNIDVEAALEQLDQIPVSMHCWQGDDVAGFENTGGPLTGGIQATGNYPGKASTPDELRADLEQAFALIPGPKRLNLHAIYLESAQPVARNEIAPEHFRTWVEWAKRHQLGLDFNPTCFSHPLSADGFTLSHPDEKVRRFWIEHCQASRRISAYFGRELGTPSVMNIWVPDGMKDLTIDRLAFRQRLLSALDEIIAEPLDQAHHIDAVESKLFGIGAESFTVGSNEFYLGYAASRGTALCLDAGHFHPTEVISDKISSAILYVPRLLLHVSRPVRWDSDHVVLLDDETQAIAHEIVRHKLLNRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTETLRKLEQNGDYTARLALLEEQKSLPWQAVWEHYCQCHDVIPGSEWLQQVRQYEETILTQRQG
What is the function of this protein?
Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
What are the official names of this protein?
L-rhamnose isomerase.
What is the protein family that this protein belongs to?
Belongs to the rhamnose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U496N_ARATH
Sequence: MGIKVSSKIKRILASTGYIPIFIFKYRYYFYFFYCKFARKFVTKKIIILKLSSIGTASGSSNPKDGADVDVREEYANAFRTESYNHFWTRVVQLSRKKSAVSSSSSSPPIESSSTSARLMSYRLFAHNLLDPDLNTITRILDVSRVGRHTRTLLSDYFLETANAFLLCTQLLKNIHHLRSKYESLKPKFHSENHNSLALIDQFTEISKWFDPFISSGSRIQLIRSGCLYLLKRLESRRDKTRAKLKLINGLTHSSGLLVLALTTTLIVTIASHAFALFLAAPTLLASQFKPAGLRNKLTKTAARLDVAAKGTYILSRDLDTISRLVTRINDEVNHVRAMAEFWVGRGSGRVRGSEEVARELKRCEESFSEELDELEEHIYLCFMTINRARNLLVKEILDSDDPPNCSFAPKSKKKL
What are the official names of this protein?
UPF0496 protein At3g49070.
What is the protein family that this protein belongs to?
Belongs to the UPF0496 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RFX1_CANAL
Sequence: MSSDQTPQNRNRGGDDSYNPRLQQQTSQIPSTGPDQGQQRERSQEQESDHEHQQAQQHLHQFQQSNLTPSTTAFPSSTSIPTFSKQDQGYHNQFSSPQSSYRKIGNFAQSSNAPFLNEPHPIYATNYQQNVPSQSQFQFDYSSPYIGQSQSQSQSQSQAQPQPHPQPQTYQQLPHYSQASVSSLPPTYQAFHSMHEASSADNDSATNITTPQKRKKQKRSESVTPNTGENELKQLALRSSNIPLSELAQKVKQLENDSTTTSVSLEQSKMKENKETQRQLFGMVWLLNSCDLAPTAVIPRNRIYARYVQVCADNNLAPVSPASFGKLVKILYPNITTRRLGMRGQSKYHYCGIKLTGDENMQSQLLNYQQKQKHQSQEQYNQQAQVGSSTSSAGLAGHQSPMSSCNSSVSYEESPGPIISRAHTPSFSPINTPTISMSKSLNDQLPSISHMKFIPNLFYLLNSNVATSSNPHEPIQLPSIYPYLSKDADHDIADTLYSLYKVHVNSIFEALRYMQLKKLFSSFSTFNNILTAPVLKLYTTESLAEWVMKCDLIMYKKMIRMLSKLQLQLLIPQEQLLQLKQIADGYIKTLSTSLINSKVSQNFVMMKLKLAKHFVNLLNRLIKVIETGQPASRILNDDNEKNTMTQDWMKLDIHGIICREMPCNDNNIDTLTYILTGEVVNLIKVKSDNEQAPTMSDFANYISNLPSRFPEVNTRLFLLLASNLLTTCLREISLSGGEGFGAWWIVRCWIDEYLAWSFEVGGFFQDDLQEIVAQQQLNVQLPPPSLSSLPQTQQQNPVIQEETGTQEESLGNIDLLETSFDFDAKTSQPYQQPSHTESLLNFETNIDNLLN
What is the function of this protein?
Transcription factor involved in DNA damage responses, morphogenesis, and virulence.
What are the official names of this protein?
Transcriptional regulator RFX1.
What is the protein family that this protein belongs to?
Belongs to the RFX family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CP132_MYCTO
Sequence: MATATTQRPLKGPAKRMSTWTMTREAITIGFDAGDGFLGRLRGSDITRFRCAGRRFVSISHPDYVDHVLHEARLKYVKSDEYGPIRATAGLNLLTDEGDSWARHRGALNSTFARRHLRGLVGLMIDPIADVTAALVPGAQFDMHQSMVETTLRVVANALFSQDFGPLVQSMHDLATRGLRRAEKLERLGLWGLMPRTVYDTLIWCIYSGVHLPPPLREMQEITLTLDRAINSVIDRRLAEPTNSADLLNVLLSADGGIWPRQRVRDEALTFMLAGHETTANAMSWFWYLMALNPQARDHMLTELDDVLGMRRPTADDLGKLAWTTACLQESQRYFSSVWIIAREAVDDDIIDGHRIRRGTTVVIPIHHIHHDPRWWPDPDRFDPGRFLRCPTDRPRCAYLPFGGGRRICIGQSFALMEMVLMAAIMSQHFTFDLAPGYHVELEATLTLRPKHGVHVIGRRR
What are the official names of this protein?
Putative cytochrome P450 132.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
Protein: RTM2B_ARATH
Sequence: MAARQQQKGTGFGVQYEDFVPKSEWKDQPEATILNIDLTGFAKEQMKVTYVHSSKMIRVTGERPLANRKWSRFNEVFTVPQNCLVDKIHGSFKNNVLTITMPKETITKVAYLPETSRTEAAALEKAAKLEEKRLLEESRRKEKEEEEAKQMKKQLLEEKEALIRKLQEEAKAKEEAEMRKLQEEAKAKEEAAAKKLQEEIEAKEKLEERKLEERRLEERKLEDMNLAEEAKLKKIQERKSVDESGEKEKILKPEVVYTKSGHVATPKPESGSGLKSGFGGVGEVVKSAEEKLGNLVEKEKKMGKGIMEKIRRKEITSEEKKLMMNVGVAALVIFALGAYVSYTFCSSSSSSSSPSSSSSSTKPE
What is the function of this protein?
Seems to not be involved in heat resistance (By similarity).  Unable to mediate restriction of long-distance movement of the pathogenic tobacco etch virus (TEV) without causing a hypersensitive response or inducing systemic acquired resistance.
What are the official names of this protein?
Inactive protein RESTRICTED TEV MOVEMENT 2, Inactive restricted tobacco etch virus movement protein 2.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Present in sieve elements.
Protein: THIC_ACIET
Sequence: MNAPDKFASLLALTREPFPASTKSYLAGSQPGLRVPVRDIQLTNGEVVSVYDTSGPYTDPAVQIDVRKGLASVRGEWIAARGDTEGYEGRVRKALDDGQKAEDGDRLAQLRAEAAALQRQPLRARSGANVTQMHYAKKGIVTPEMEYVALRENGRREWMQQYMQDAAREQRLAGNPLGASIPKIITPEFVRDEVARGRAIIPANINHPEVEPMAIGRNFKVKINANIGNSAVTSSIEEEVEKLVWAIRWGADNVMDLSTGKNIHTTRDWIVRNSPVPIGTVPIYQALEKVGGIAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLAYIQLTAARRTGIVSRGGSIMAKWCMAHHKESFLYTHFEDICDIMKAYDVAFSLGDGLRPGCASDANDEAQFAELHTLGELTQIAWKHDVQTMIEGPGHVPMHMIQANMTEQLKTCHEAPFYTLGPLTIDIAPGYDHIASAIGAAMIGWMGTAMLCYVTPKEHLGLPDRDDVKQGIIAYKIAAHAADVAKGHPGARARDDALSQARFDFRWQDQFNLGLDPDTAKEYHDETLPKDSAKVAHFCSMCGPKFCSMKITQEVREFAQQGLQSKAEEFNRTGGELYVPIHRAD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: PEPL_MOUSE
Sequence: MHSLFRKRNKGKYSPTVQTRSISNKELSDLIEQLQKNADQVERNIVDTEAKMQSDLARMQEGQLPEHRDAALQNVSDSEKLLYVLEADSAIAKHMKHPQGDMIAEDIRQLKERVTNLRGKHKQMYSLAVKEADPRVNWDTLVDEKLDKLSSQSFGTDLPLVDSQVEQHNIFHNEVKAIGPHLAKDKEQNSELQAKYQKLLTASQARQQHLSSLQDYMQRCTNELYWLDQQAKGRMQYDWSDRNLDYPSRRRQYENFINRNLEAKEERINKLHTEGDQLLTAEHPGRNSIEAHMEAVHAEWKEYLNLLICEESHLKYMEDYHQFHKDMKDAQELLRKVDSDLNQKYSPDFKDRYQIELLLRELDDQEKALDKYEDVVRGLQRRGQQVVPLKYRRETPLKPIPVEALCDFESDQGLISRGYSYTLQKNNGESWELTDSTGKKLAAPAVCFIIPPTDPEALALADSLGSQYRSVRQKATGSKHALQQRHEVLRTENPGDASDLQGRQLLAGLDKVASDLDRQEKAITGILRPPLEQGRAIEDSAERAKGLKNITNELLQIEPEKTQCTAECEAFVQALPASGTAPLLKTRVEDTNQKYERLVWLLEAAQEKVDVANRLENSLQRGRELLASYENRLIQDDTMPESGHVLDRKRQELEAMASELQAHKSLLGEVGKNLQVAKQCSSSLASRFQEHCPDLERQEAEVHKLNQRFNNLSQQVERRAQSLQSARAAYDEYCSGYNRVLQFLAKTPSYEPQETDSLGQMETKLKNQKNLLDELASREQEVQKVYADSQQYQQAVKDYELEAEKLRSLLDLENGRNSHVNKRARLQSPAAKVKEEEAALAAKFTEVNAINRQRLQNLEFALNLLRQQPEAGVTHETLQGGKLSSGMEETWKIKKELEEEIERRQQLENEVKSAQEEIQTLKDQGPQESLVRKEVLKKVPDPALEESFQQLQQTLAEEQHKNQLLQEELGALQLRLQALEQETRDGGQEYVVKEVLRIEPDRAQEDEVLQLREELEALRRQKGAREAEVLLLQQRVAALAAEKSRVQEKVTEREVVKLQNDPQLEAEYRRLQEEHQREGTLREKQEEELSFLQAKLRRLEKERAMAEGKITVKEVLKVEKDAAVEREVNDLTRQYEDEAAKARSGQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKFRGAEEQLKSYQSELEALRNRGPQVEVKEVTKEVIKYTTDPETEQELQRLREEIMDKTRLIERCDLEIYQLKQEIQALKDTKPQVQTREVVQEILQFQEDPQTKKEVESLRIQLSEEQKKQVDLEGERASQEEKIKRKEEELAQQRKERVVRQEVVQYEDEPDLRAEVTAFTNSIDAELRQIDKLHVELRRLQHRRAELERQLEELERERQARRAAELEVQRLQQRLAALEQEEAKTGEKVTHTQKVVLQQDPQQTREHALLRAQLEEERHRRQLLEGELEPLRRKLAALEKAEIKEKVVFSESVQVEKGDTEQEIQRLKKSLEEESQSKRELDSEVTRLEAKLSELEFYNSKSSKELDFLREENHKLQLERQNLQLETRRLQSEIEMAATETRDLKNITTIDSGTHLNSRLWSLEKELDDLKKMSKDKDLEIDELQRRLGSVAVKREQRENHLRRSIVVIDPDTGRELSPEEAHRAGLIDWKMFVKLRSQECDWEEISVKGPNGESSVIHDRKSGKKFSIEDALQSGRLTAAQYDRYVNKDMSIQELAVLVSGQK
What is the function of this protein?
Component of the cornified envelope of keratinocytes.  May link the cornified envelope to desmosomes and intermediate filaments.  May act as a localization signal in PKB/AKT-mediated signaling.
What are the official names of this protein?
Periplakin.
What is the protein family that this protein belongs to?
Belongs to the plakin or cytolinker family.
What are the subcellular locations of this protein?
Cell junction, desmosome. Cytoplasm, cytoskeleton. Cell membrane. Cytoplasm.
Protein: SCX1_CENBC
Sequence: KDGYPMDNKGCKIACVINNQYCETECVTVLKGKKGYCYFWKLACYCEGLPNWAKVWDRATNKCRA
What is the function of this protein?
Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing.
What are the official names of this protein?
Toxin Cbi1.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: TCPG_XENLA
Sequence: MMGRPVLVLSQNMKRESGRKVQSGNINAAKTIADIIRTCLGPRAMMKMLLDPMGGIVMTNDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEQFLEQQMHPTVIISAYRKALDDMVNTLKEISTPVDTNDRELMLKIINSAINTKAIKLWADMACGIALDAVKTVELEENGRKEIDIKKYAKVEKIPGGIIEDSCVLRGVMVNKDVTHPKMRRLIKNPRIILLDCSLEYKKGESQTEIEITREEDFARILQMEEEYIQQVCEDIIRLKPDVVITEKGISDLAQHYLVKANITAVRRVRKTDNNRIARACGARIASRTDELREEDVGTGAGLFEIKKIGDEYFTFITDCKDPKACTIVLRGASKEILAEVERNLQDAMQVCRNVVIDPYLVPGGGASEMSVAHILTEKSKTMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRILTSLRAKHTQEGCQTWGVDGEAGVLADMKELGIWEPLAVKLQTYKTAVETAILLLRIDDIVSGHKKKGEDHGRQPAAAPEAPQQAE
What is the function of this protein?
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis.
What are the official names of this protein?
T-complex protein 1 subunit gamma, TCP-1-gamma, CCT-gamma.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_SYNS3
Sequence: MARIAGVDIPRDKRIEVALTYIYGIGSTRAKTILTKAGVNPDIRVKDLEDNDVQKLRNATESFTIEGDLRRQEGMALKRLQDIGCLRGRRHRMSLPVRGQRTRTNARTRRGARKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: TCPR1_RAT
Sequence: MPTSMLWAVDLFGRVYTLSTAGQYWELCKDVQLEFKRVSAATQCCWGIACDNQVYLYVCSSDVPIRHREEAYENQRWNPMGGFCEKLLPSDRWSWSDVSGLQHRPLDGVALPSPYWEWESDWYVDENFGGEPTEKGGWTYAMDFPATYTRDKKWNSCVRRRKWIRYRRYKSRDTWAKIPSKDDPKELPDPFNDLSVGGWEITEEPVGRLSVWAVSLQGKVWYRENVSHPNPEGSSWSLVDTPGEVVQISCGPHDLIWATLWEGQALVREGICRNNPKGNSWSIVEPPGSENGIMHVSAGVSVVWAITKDRKVWFRRGVNSHNPCGTSWIEMVGEMTMVNVGLNDQVWGISCEDRAVYFRQGVTPSELSGKTWKAIVVGRESDRSHSGSSSSLLSAGCFFGEEVRGSGTESAPSDTDASSEVERQGPERSLPKESLDNSRNLKGSSSKGHESTRNTEDPMENACLAEGQAKAPKTSGPDECHGPAPTPAELPWTNIDLKEPKKASNQPAAGFPETSGLSSLGLFPMGMEEPYGADDHPLWAWVSGGGCAVEAGSALKWFTVQSGLSPSVQTLSLSITPAQTAAWRKQIFQQLTERTKRELESFRHYEQAVEQSVWVKTGALQWWCDWKPHKWVDVRVALEQFTGHDGARDSILFIYYVVHEEKKYLHVFLNEVTVLVPVLNEAKHSFALYTPERTRQRWPVRLAATTEQDMNDWLTLLSLSCCESRKVHGRPSLQAIWSVTCKGDIFVSEPSPDLEAHEHLLPCDQMFWRQMGGHLRIIEANSRGVVWGIGYDHTAWVYTGGYGGGCFQGLASSTSNIYTQSDVKSVYIYENQRWNPVTGYTSRGLPTDRYMWSDVTGLQECTKAGTKPPSLQWTWVSDWYVDFSVLGGTDQEGWQYASDFPASYHGYKTMKDFVRRRCWARKCKLVTSGPWLEVAPIALSDVSIIPESADANGRGHNIALWAVSDKGDVLCRLGVSELNPAGSSWLHVGTDQPFASVSIGACYQVWAVARDGSAFYRGSVSPSQPAGDCWYHIPSPPKQKLTQVSVGQTSVYALDENGNLWYRAGITPSYPQGSSWEHVSNNVRKVSVGPLDQVWVIANKVQGSHGLSRGTVCRRMGVQPREPKGQGWDYGIGGGWDHISVRANATRAPRNMSRDQEAHGPGPVCC
What is the function of this protein?
Tethering factor involved in autophagy.  Involved in autophagosome maturation by promoting the autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes.  Also involved in selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure biogenesis and maturation (By similarity).
What are the official names of this protein?
Tectonin beta-propeller repeat-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the TECPR1 family.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by the fusion between autophagosomes and lysosomes (By similarity).
Protein: TRPA_ECO57
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADTLELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPKKMLAALKAFVQPMKAATRS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: NU3M_AVACL
Sequence: MNLSLTLMTDVALALLLVMIAFWLPQLNIYTEKYSSYECGFDPMGSARLPFSMKFFLVAITFLLFDLEIALLLPLPWASQTTNLKLMLTMALLLISILAAGLAYEWSQKGLEWEE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YA034_YEAST
Sequence: MAAVHLYIISFTALMISSTSEMGGYPKCSVNIEVDLIVGADMVVLIVLTQFQRVITQLPNKCQLIFNASYLPFLFTRTIKISKVERQQGERSKMAMKSKIELKLIHKGSHFYIQLPI
What are the official names of this protein?
Putative uncharacterized protein YAL034C-B.