PharMolix/UniProtQA huggingface dataset:
Protein: COX1_OSPRO
Sequence: MFITRWLFSTNHKDIGTLYLLFGAWAGMVGTALSLLIRAELGQPGTLLGDDQIYNVIVTAHAFVMIFFMVMPIMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSTVEAGAGTGWTVYPPLAGNLAHAGASVDLAIFSLHLAGVSSILGAINFITTIINMKPPALTQYQTPLFVWSVMITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGHPEVYILILPGFGMISHIVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVDTRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPALLWALGFIFLFTIGGLTGIVLANSSLDIVLHDTYYVVAHFHYVLSMGAVFAIMGGFVHWFPLFTGYTLNDLWAKIHFSIMFVGVNMTFFPQHFLGLSGMPRRYSDYPDAYTTWNIISSIGSFISLTAVILMVFIIWEAFASKREVATVELTTTNIEWLYGCPPPYHTFEQPVFVKV
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 1, Cytochrome c oxidase polypeptide I.
What is the protein family that this protein belongs to?
Belongs to the heme-copper respiratory oxidase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SYH_OPITP
Sequence: MATFQSLPGFREFYPDALARRNHIFRLWRQTAVAFGFAEYDAPVLEPLELYKTKSGDEIEAQLFSFTDKGGREVALRPEMTPTVCRMVGAKANALKRPIKWFSIAEYYRYERAQKGRERAFFQFNADLFAEPGPEAEIELIALLTQCLKAFGLTEQDFYIRLSDRNLWFFYLEALGLDEPRIRAVLSAVDKFEKVGDDAFKPYAEQFGPLDLALKQRVLEFLQIKTLASLEQTLAPLGGEKLAARLGDWRKLLDGLAAMGLSPFIEVDLGVVRGLAYYTGFVFEAFDRKGELRAIAGGGRYNDLVKKLGGPDLPAVGFAIGDVTLGLLLDARGLMPAFVQASDVYCVIGGAAERQAAFADVNALRAAGFKVDYPLKDVPFGKQFKLAADSGAKLALIYGPDELAKNVVKLRDLTTRTETDVPREQVQAMVRDFFSTD
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEAP1_MOUSE
Sequence: MQPEPKLSGAPRSSQFLPLWSKCPEGAGDAVMYASTECKAEVTPSQDGNRTFSYTLEDHTKQAFGVMNELRLSQQLCDVTLQVKYEDIPAAQFMAHKVVLASSSPVFKAMFTNGLREQGMEVVSIEGIHPKVMERLIEFAYTASISVGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLDPSNAIGIANFAEQIGCTELHQRAREYIYMHFGEVAKQEEFFNLSHCQLATLISRDDLNVRCESEVFHACIDWVKYDCPQRRFYVQALLRAVRCHALTPRFLQTQLQKCEILQADARCKDYLVQIFQELTLHKPTQAVPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQQNCTC
What is the function of this protein?
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that regulates the response to oxidative stress by targeting NFE2L2/NRF2 for ubiquitination (PubMed:9887101, PubMed:12682069, PubMed:15282312, PubMed:15367669, PubMed:15581590).  KEAP1 acts as a key sensor of oxidative and electrophilic stress: in normal conditions, the BCR(KEAP1) complex mediates ubiquitination and degradation of NFE2L2/NRF2, a transcription factor regulating expression of many cytoprotective genes (PubMed:9887101, PubMed:12193649, PubMed:14764894).  In response to oxidative stress, different electrophile metabolites trigger non-enzymatic covalent modifications of highly reactive cysteine residues in KEAP1, leading to inactivate the ubiquitin ligase activity of the BCR(KEAP1) complex, promoting NFE2L2/NRF2 nuclear accumulation and expression of phase II detoxifying enzymes (PubMed:12193649, PubMed:20498371, PubMed:22014577, PubMed:29590092).  In response to selective autophagy, KEAP1 is sequestered in inclusion bodies following its interaction with SQSTM1/p62, leading to inactivation of the BCR(KEAP1) complex and activation of NFE2L2/NRF2 (PubMed:20421418, PubMed:20173742, PubMed:24011591).  The BCR(KEAP1) complex also mediates ubiquitination of SQSTM1/p62, increasing SQSTM1/p62 sequestering activity and degradation (PubMed:28380357).  The BCR(KEAP1) complex also targets BPTF and PGAM5 for ubiquitination and degradation by the proteasome (By similarity).
What are the official names of this protein?
Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2.
What is the protein family that this protein belongs to?
Belongs to the KEAP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Mainly cytoplasmic (PubMed:17903176). In response to selective autophagy, relocalizes to inclusion bodies following interaction with SQSTM1/p62 (PubMed:20495340, PubMed:20421418, PubMed:20173742).
Protein: RS8_BIFLS
Sequence: MTMTDPIADMLTRLRNASAAKHETVDMPYSKFKANIAEILKREGYIKDFTAKEAKVGQTLEVTLKYGPNGERSIQGIKRISKPGLRRYAKSDSLPMPLGGLGIAIISTSSGLLTQKECLDRGIGGEIVAFVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NDK_SHEPC
Sequence: MAIERTFSIIKPDAVAKNHIGAIYNRFETAGLKIVAAKMLHLTKEQAEGFYAEHSERGFFGALVAFMTSGPIMVQVLEGENAVLAHREILGATNPAQAAPGTIRADFAESIDENAAHGSDAVESAAREIAYFFSAEELCPRTR
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_EHRRG
Sequence: MRFTLSWLMQYLDTDASLDFIISKLSDIGLEVDSVDCKKHLQSFVVVEVIDVVPHHAADKLKVCQVYDGVQTFQVVCGASNVKVGMKSVLAYVGSVIPKNQTVIKVAKLRGVDSYGMLCSRDELGITENDSTDEGIIELSDNTYNVGESFFSCDPVIELNITPNRGDCLGVYGIARDLAAAGVGKLKSVNFCDITFDNTCYISPIEICLEVQGVVKGVYIKGIRNCETPKWLKEYLFSCGVKSISCVVDIINYIMLSFNRPLHIYDADKIAGKLVFRKIDDQIEFFALNDKKYLLGKENIIAVDLANRIHSIVGVIGSEYSKCLFDTENIFLECAWFDPVDIALSSRKIKLSTDSSYRLERFVDPEFLQDGLKLATKMILEYCGGSPSSIVSVQNYVHNDILLNFSPDSVRNIGSVSITRDEIFDFLCNIGCVVKNHDCDIWIVIPPSWRSDLKHSFDLVEEVLRLYGYDKILENPIPISNIEFPDNLHNKLRSVLLSQGMMEVVTWSFTNLEFAKKFGYDSDIMLIDNPINNNMNLMRPSVLLNLLQVISENQAYGNNDAAIFEIGQIYNINSVCGDNNYVVSGVRYGDNLPRNFYKTDRSVDIFDVKSDFFKVLQEMNIGYDSVDLVRSTKSYLHPMKSADVYFNNILIGYFGELHPSIVHLYEIKRPIVCFEVFLYKIPVVDLTRKEFVELRYQSVKRDFAFLVSKNVNIQCLIEVAKKTNVQLIEDVSIFDIYEGNGIDKGMLSVALSVTFRSVDHTLNDQEIKDASDLIISAISKGFNGILRSC
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SMCO3_HUMAN
Sequence: MAQSDFLYPENPKRREEVNRLHQQLLDCLSDSFDVTNKLTEVLNMHLGCRLASIEMKRDGTIKENCDLIIQAIMKIQKELQKVDEALKDKLEPTLYRKLQDIKEKETDKIAIVQKVISVILGEATSAASAVAVKLVGSNVTTGIINKLVTVLAQIGASLLGSIGVAVLGLGIDMIVRAILGAVEKTQLQAAIKSYEKHLVEFKSASEKYNHAITEVINTVKHQMK
What are the official names of this protein?
Single-pass membrane and coiled-coil domain-containing protein 3.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ST14_SOLTU
Sequence: MFVLSTAMACLVYIYIYIYDEEKKRELKVRNKMTNLLFFQFLLLTTASSLTHISAQTVPPPPPPPTSAATPPSRAAQEFLDAHNKARSEVGVGPLTWSPMLAKETSLLVRYQRDKQNCSFANLSNGKYGGNQLWASGTVVTPRMAVDSWVAEKKFYNYENNSCTGDDKCGVYTQIVWKKSIELGCAQRTCYEGPATLTVCFYNPPGNVIGEKPY
What is the function of this protein?
May protect the outer tissues of the pistil from pathogen attack.
What are the official names of this protein?
STS14 protein.
What is the protein family that this protein belongs to?
Belongs to the CRISP family.
Protein: VSGP_EBOSB
Sequence: MEGLSLLQLPRDKFRKSSFFVWVIILFQKAFSMPLGVVTNSTLEVTEIDQLVCKDHLASTDQLKSVGLNLEGSGVSTDIPSATKRWGFRSGVPPQVVSYEAGEWAENCYNLEIKKPDGSECLPPPPDGVRGFPRCRYVHKAQGTGPCPGDYAFHKDGAFFLYDRLASTVIYRGVNFAEGVIAFLILAKPKETFLQSPPIREAANYTENTSSYYATSYLEYEIENFGAQHSTTLFKINNNTFVLLDRPHTPQFLFQLNDTIQLHQQLSNTTGKLIWTLDANINADIGEWAFWENKKISPNNYVEKSCLSKLYRSTRQKTMMRHRRELQREESPTGPPGSIRTWFQRIPLGWFHCTYQKGKQHCRLRIRQKVEE
What is the function of this protein?
Viroporin that permeabilizes mammalian cell plasma membranes.  It acts by altering permeation of ionic compounds and small molecules.  This activity may lead to viral enterotoxic activity.
What are the official names of this protein?
Pre-small/secreted glycoprotein, pre-sGP.
What is the protein family that this protein belongs to?
Belongs to the filoviruses glycoprotein family.
What are the subcellular locations of this protein?
[Small/secreted glycoprotein]: Secreted. SUBCELLULAR LOCATION: [Delta-peptide]: Secreted.
Protein: ALF1_STAEQ
Sequence: MNKEQLEKMTHGKGFIAALDQSGGSTPKALKEYGVNEDQYSNEDEMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVEGKYTGDYLADKGVVPFLKVDKGLAEEKNGVQLMKPIDDLDATLNRANERHIFGTKMRSNILELNEQGIKDVVEQQFEFAKKIIAKGLVPIIEPEVNINAKDKSEIEKVLKAEIKKGLDSLNDDQLVMLKLTIPTEANLYKDLADHPNVVRVVVLSGGYSRDEANKLLKDNDELIASFSRALASDLRASQSQEEFDKALGDAVDSIYDASVNKN
What are the official names of this protein?
Fructose-bisphosphate aldolase class 1, Fructose-bisphosphate aldolase class I, FBP aldolase.
What is the protein family that this protein belongs to?
Belongs to the class I fructose-bisphosphate aldolase family.
Protein: AROB_RHIME
Sequence: MTSHVMPTAERKVRVDLAERSYDILIGPGLIAAAGKEIASRLKGRKMAVITDENVAPRYLEPLMASLGESGIEAVSLILPAGEKTKSFEHLIPVCEAILGARIERNDAVIALGGGVIGDLTGFAAGIVRRGSRFIQIPTSLLAQVDSSVGGKTGINSAHGKNLIGVFHQPDLVLADTAALDTLSPREFRAGYAEVAKYGLIDKPEFFEWLEKNWQAVFAGGPARIEAIAVSCQAKADVVAADERENGRRALLNLGHTFGHALEAATDYDSKRLVHGEGVAIGMVLAHEFSARMNLASPDDARRVEAHLKTVGLPTRLADIPGALPPADRLMEAIAQDKKVKGGKLTFILTRGIGQSFVADDVPSSEVLSFLTEKHPR
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECBL_MYCTO
Sequence: MTDRTDADDLDLQRVGARLAARAQIRDIRLLRTQAAVHRAPKPAQGLTYDLEFEPAVDADPATISAFVVRISCHLRIQNQAADNDVKEGDTKDETQDVATADFEFAALFDYHLQEGEDDPTEEELTAYAATTGRFALYPYIREYVYDLTGRLALPPLTLEILSRPMPVSPGAQWPATRGTP
What is the function of this protein?
Chaperone component of an atypical, type II toxin-antitoxin chaperone (TAC) module, probably required for antitoxin HigA1 to neutralize its cognate toxin HigB1.
What are the official names of this protein?
SecB-like chaperone MT2006.
What is the protein family that this protein belongs to?
Belongs to the SecB-like family.
Protein: MBTB_MYCSS
Sequence: MEAVVTSSQTVRAEVAELLGIEESALDPDADLIASGLDSIRMMSLSGRWRKQGIDVRFAAMAANPTVAAWTRLVGERTAESPGAATQSGDTAASAGDPDAPFPLAPIQHALWVGRNELTELGGVAAHLYVEFDGAGVDPERLRTAAAALAARHPMLRVDILGDGMQRISDRDLPVKVTDLRHLDVADAEQQLEVIRHAKSHQLLEGEVLELALTLLPDGRTRLHVDLDMQAADAVSYRNFMADLAALYRGAQLPELQYTYRQYRSAFTATPAPTVDEDRRWWTERIPDLPEPPALPLVPRAEQRDPRRGTRRWHFLDTDIRDRLFAAARARGITPAMAFAASYAGTLARWSTSRHFLLNLPMFGREPFHPDVDKLVGDFTSSLMLDVDFTEAHTPAQRARVMQEALHTSAEHATYSGLSVLRDLSRHHGSPSLAPFVFTSALGLGDLFAGDVTDQFGTPVWHISQGPQVLLDAQVTPFDGGLLVNWDVREDAFRPGVIDAMFAYQLAELERLAADDAAWDAADPPAVPPAQRAVRDAVNDTGARRSDDALHDGFFRTAAHTPDATAVIGSTGTLTYAELRERVLAVTGALQVAGIKPGDTVAVMGPKCADQVTALLAIHAAGAVYVPIGADQPADRADSILQTAGVRMALACGDEPPTFLPALTIAEAVRVGSRVHGVTPATVEPDRVAYVLFTSGSTGAPKGVEVTHAAAMNTLEFINDHFGIGPSDRSLALSTLEGDLSVLDVFGMLRAGGSLVVVDEAQRRDPDSWARLIAEHSVTVLHWMPGWLEMLLEVGGALPSVRVVPTGGDWVRTEMVRELRRAAPGVRFAGLGGATETAIHNTICEPGELPREWSAVPFGRPLPNNACRVVAADGADCPDWVPGELWVGGRGIARGYRGRPDLTAERFVVHDGRTWYRTGDLVRYLPDGQIDFVGRADHRVKISGYRIELGEVEAALRRIAGVEAAVAAVLTAPGDGRGEQLAAIVRASSPAVTVDELTRRMAELVPPHMVPSHIALVEAVPFTVGGKIDRRAVTAELTRSMAERANAQAPTYRVPSTALERALADIVSTVLDRDSVGADDDFFELGGDSVLATQAVARIREWLDSPGVMVTDIFAARRVGALARRLVDHESGSDRLEGVAELYLEVADMNSADVASALHSTSAQASR
What is the function of this protein?
Involved in the initial steps of the mycobactin biosynthetic pathway.  Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores (By similarity).
What are the official names of this protein?
Phenyloxazoline synthase MbtB, Mycobactin synthetase protein B.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family. MbtB subfamily.
Protein: CSEC_STRAW
Sequence: MRGNLRRPGPAGTAGPGRTGIRTSADGGRARPRTGAGTGVRAGVRSGVVGVGAGIRTGVRWKISAAIALVGALVALALSLVVHNAARVSMLDNARDLADERIQVAERMYEAGRAQSFGVKLDDPAIPRDLMMKVTQGRRATYVADGPHGVPDIWAAVPLKDGRVLSLHTRFTDRSADIMKDLDQALIIGSIAVVFGGSALGVLIGGQLSRRLRKAAAAANQVAQGERDVRVRDAIGGVVRDETDDLARAVDAMADALQQRIEAERRVTADIAHELRTPVTGLLTAAELLPPGRPTELVRDRAQAMRTLVEDVLEVARLDGASERAELQDIMLGEFVSRRVAAKDADIEVRVVHESEVTTDPRRLERVLFNLLANAARHGKPPIEVSVEGRVIRVRDHGPGFPEELLADGPRRFRTGSTDRAGHGHGLGLTIAAGQARVLGARLTFRNVRPAGAPGDVPAEGAVAVLWLPEHAPTNTGSFPMLPLSGG
What are the official names of this protein?
Sensor protein CseC.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL36_STRPG
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: DCTA_PARXL
Sequence: MKKPIHKVLYVQVIVAIIIGIGLGHFYPDLAVDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMEDMKKVGRVGGKALLYFEIVSTFALVLGLIATHVLKPGVGFNIDPATLDGKAVASYAAKAHGQTTVDFLMHIIPDTLVSAFAQGEILQILLIALLFGAVLATAGEKGKVVTGFIDGLSHVLFGIVRIITKLAPIGAFGAMAFTIGKYGIGSLLPMLKLIGTFYLTSVVFVVVVLGIIARAVGFNILRFVAYIKEEMLIVLGTSSSEAALPQLMLKLERLGCSRSVVGLVVPTGYSFNLDGTNIYMTMAVLFIAQATNTDLTWTQQLTLLAVTMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRSKLNAALRGDVAIKEPAGV
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLA3_TRIAB
Sequence: GFDCPFGWSSYEGYCYKVYNKKMNWEDAESFCREQHKRSHLVSFHSSGEVDFVVSKTFPILRYDFVWMGLSDIWKECTKEWSDGARLDYKAWSGKSYCLVSKTTNNEWLSMDCSRTRYPVCKFXG
What is the function of this protein?
Potent platelet activator that aggregates platelets via both GPIbalpha (GP1BA) and GPVI (GP6).  Induces a tyrosine phosphorylation profile in platelets that resembles this produced by collagen, involving the time dependent tyrosine phosphorylation of Fc receptor gamma chain (FCGR1A), phospholipase Cgamma2 (PLCG2), and LAT.
What are the official names of this protein?
Snaclec alboaggregin-A subunit beta, Alboaggregin-A subunit 3, AL-A subunit 3.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: FTHS_CLOPE
Sequence: MKNDIEIAQSAKMEPIINIAKKIGLGEDDIELYGKYKCKISLDAIKKLENNKDGKLVLVTAINPTPAGEGKSTVTVGLGQALNKIGKNTVIALREPSLGPVFGIKGGAAGGGYAQVVPMEDINLHFTGDMHAITSANNLLCAAIDNHIHQGNLLRIDSRRIVFKRVMDMNDRALRNIVVGMGGKINGFLREDGFMITVASEIMAILCMASDLEDLKERMGNILIAYNLDGEPVYAKELEVQGAMALLMKDAIKPNLVQTLENTPAIIHGGPFANIAHGCNSIIATKTALKMSDITITEAGFGADLGAEKFLDIKCRYGNLNPDCVVLVATIRALKHHGGVKKDELNISNVDALNKGMKNLEKQIENIKAYGVPVVVAINKFITDSDEEVKAIEDFCKNIGVEVSLTEVWEKGGEGGIDLANKVIKTMETEPSNFKMIYDSEESIKDKILKIVQTIYGGKGVNYTPQALKQIAEIEKFNLDKLPICMAKTQYSLSDNPSLLGRPENFDITVKEVRVSNGAGFIVVLTGDVMTMPGLPKVPAANRMDIKDNGEIVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: RF1_XANC8
Sequence: MTPTLRRKLEALAERREELQHLLSDPEVVSNNDKFRSLSRELSQLEPVALAMQEEARAKADLSAAEAMRNDPEMRELAEEEILAAQARLDELDAQLALLLVPRDPRDEGNLFLEVRAGTGGDEAAIFAGDLFRMYARYAERQGWKVEIESDSPGEHGGYKEVVARVVGRGAYSRLKFESGTHRVQRVPATESQGRIHTSAATVAIIPEADDVEEIVINPADLKVDTFRSSGAGGQHVNKTESAIRITHVPSGVVVECQTERSQHANRDKAMKRLKAQLVEAERSKAAAAKAQTRKLQVGSGDRSQRIRTYSFPQGRITDHRVEGLTLYDLPNIIEGDLDALIARLLHEHQADELARLSEGT
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCUP_MYCLB
Sequence: MSTRRELLESPYLAAVSGRKPCRVPVWFMRQAGRSLPEYRALRERYSMLAACFEPEVACEITLQPLRRYDVDAAILFSDIVVPLCAAGIDLDIVPDVGPVIGDPVRTATDIHAMKPLEPQAIQPIFQAISLLVAALGDVPLIGFAGAPFTLASYLVEGGPSRNHPRTKAMMLAEPASWHTLMDKLTDLTLGFLLGQIDAGVDAIQVFDSWAGTLSLSDYRQYVLPHSARIFATVAEHGVPMTHFGVGTADLLGAMSAAVRSGEKPGHQAVVGVDWRTSLTDAAARVEPCTALQGNLDPVVLLAGWPAVERVARTVVDDGRRAVVAGAAGHVFNLGHGVLPETDPGVLSELVSFIHSL
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_PARXL
Sequence: MPTAYKRVLLKLSGEALMGDDAFGINRATIERMVADVAEVVRLGTQLAVVIGGGNIFRGVAGGAAGMDRATADYMGMLATMMNALALQDAMRHAGIEARVQSALRMDQVVEPYIRPRAIRQLEEGKVVIFAAGTGNPFFTTDTAAALRGSEIGAEVVLKATKVDGVYSADPKKDPSATRYTTISFDEAIGRNLQVMDATAFALCRDQKLPIRVFSIVKPGALKRIVQGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGPS1_DICDI
Sequence: MIKRALAPIVQPQRLFAALMVIGGGGRSATTTTTTTTKACGNGSSQSPPSTPLLSSKSSTITSNKKSAIPSSHLYIPKKSTLDSRQIGNYSREYSTSSSSSSKKSIFNDTYLNDLFWQLSSQGPAFEVNPNNIDFIQEPIDFYNHLIDGVKRSKKRITMASLYLGTSKQEIELVKEMKLAMERNKELKIHILLDGLRGTRIGLDKESSATILGELLSLYSDRVTISMYHTPDLNGILKKVLPPRINETIGVQHIKTYIFDDDLLLSGANLSKDYFTNRQDRYVLIRSTSTVSNYFNEIVEIIGSLSLHVDKDNRNQLLLSSGSIDPVTQSNEFKNLAYTKLSTLLKSHSYYPSNSNSNSSVDSPFDCNNINNGETTWIFPTIQMGPFNIRQDEVVTSHIFESVPNDSKFFITSPYFNLTENYLNLILTGKPKLDIITCSPQANGFYGSKGLSSAVPDCYAIIEKRFLQRVQDTDNGDRISVQEYIRDKWTYHAKGLWIQVKNQQHPSITLIGSPNFGSRSVEKDLEAQIILITQNKQLQQKMENEKNYLWTDTQNANLELFEKRKVSLMVRFLVYIFGNYL
What is the function of this protein?
Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
What are the official names of this protein?
Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase 1, PGP synthase 1.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
Protein: SAHH_PSEPF
Sequence: MSAVITPADFNDYKVADISLAAWGRRETIIAESEMPALMGLRRKYASEQPLKGAKILGCIHMTIQTAVLIETLVALGAEVRWSSCNIFSTQDQAAASIAAAGIPVFAWKGETEEEYEWCLEQTILKDGQPWDANMILDDGGDLTELLHKKYPQVLDRVHGVTEETTTGVHRLLDMLAKGELKIPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSAQSLRQEGMIVKVSEVDPICAMQACMDGFELVSPFIDGINDGTEASIDKALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGAGSFDPQNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIFLFGQKYADLSPAQKAERLTVEVLPKKLDEEVALEMVRGFGGVVTQLTKQQADYIGVTVEGPFKPHAYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR5_ARCFU
Sequence: MPKFDYAKAGVDIREEERAIKSLASVIKHVRSGFGRPILTSHYAGVIDCGDFGITITTDGVGSKILVAEKMRKFDTIGIDCVAMNVNDLLAIGSEPLAMVDYIAIEKPDEWIMAEIAKGLEEGCRIANITLLGGETATLPEIIRGFDLAGTAIGWVKKDAIITGEKIEEGDVIFAIPSSGIHSNGLTLARKVVEAAGLSYHDKFGDKTIGEELLTPTRIYMEILDVLRECEVHGLAHITGSGLLKLKRLKNMKYVIDKPLKPQEIFRFIQKLGEVEEAEMYRTFNMGMGFMVILPEDEADKLKKLCEGRVVGYVEKGEGVYVKDLRLDA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_STRA5
Sequence: MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNYIRILVGDRVTVEMSPYDLTRGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NA1G2_STIGI
Sequence: MNRLIILVFAAVFLTLASAEVSEDVNMAKRGVPCRCDSDGPHVRGNTLTGTVWVFGCPSGWHKCQKGSSTCCKQ
What is the function of this protein?
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation during signal transduction.
What are the official names of this protein?
Delta-stichotoxin-Sgt2a, Delta-SHTX-Sgt2a, Gigantoxin II, Gigt II, Gigantoxin-2.
What is the protein family that this protein belongs to?
Belongs to the sea anemone sodium channel inhibitory toxin family. Type I subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: UBIC_PSEA6
Sequence: MQKTISHAFPLGDVTWSNQGRLSIPNAHLESWLLNTGSLTQRLQTRCNDFKVQLVSQRQELATPAEYIQLGVSKMSQQKENWQVREVILHGDNQPWVFARSIIPQALCEADFLELGDKPLGHLIFNDDRFKRQPFQLMCLQPDEAFLHEYGLPPLTEIWGRRSVFCYQQYAMMVAELFLPKAPAYRDSNFDR
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Probable chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.