PharMolix/UniProtQA huggingface dataset:
Protein: PURA_SHIBS
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TASP1_HUMAN
Sequence: MTMEKGMSSGEGLPSRSSQVSAGKITAKELETKQSYKEKRGGFVLVHAGAGYHSESKAKEYKHVCKRACQKAIEKLQAGALATDAVTAALVELEDSPFTNAGMGSNLNLLGEIECDASIMDGKSLNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYRWAVDHGIPSCPPNIMTTRFSLAAFKRNKRKLELAERVDTDFMQLKKRRQSSEKENDSGTLDTVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCWAENTGAHNPYSTAVSTSGCGEHLVRTILARECSHALQAEDAHQALLETMQNKFISSPFLASEDGVLGGVIVLRSCRCSAEPDSSQNKQTLLVEFLWSHTTESMCVGYMSAQDGKAKTHISRLPPGAVAGQSVAIEGGVCRLESPVN
What is the function of this protein?
Protease responsible for KMT2A/MLL1 processing and activation (PubMed:14636557).  It also activates KMT2D/MLL2 (By similarity).  Through substrate activation, it controls the expression of HOXA genes, and the expression of key cell cycle regulators including CCNA1, CCNB1, CCNE1 and CDKN2A (By similarity) (PubMed:14636557).
What are the official names of this protein?
Threonine aspartase 1, Taspase-1.
What is the protein family that this protein belongs to?
Belongs to the Ntn-hydrolase family.
Protein: ODO1_STAAW
Sequence: MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLFSIIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPKLEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNTERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALVPMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPEDGSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDDTQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIGFTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDLVGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEMHSFIEQVQKELRQAHDKINKADKMDNPDMEKPADLALPLQADEQSFTFDHLKEINDALLTYPDGFNILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHRHAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEAQYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAAENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSGGFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIEALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDGEIHKLVQNKIIENALKNN
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: ATL57_ARATH
Sequence: METKHLRKLLQLYQACGGEQELTKTVQNVTSSPLTPTPPPQPPSALDSTMALTIFILLVALFFMGFFSVYFRHFADSSSSTVDISSMPRTRSSRMSPRRLSTSVVVSRPYSFRRGLDSQAVRSLPVYRYTKAAKQRNEDCVICLSDFEEGETVKVIPHCGHVFHVDCVDTWLSSYVTCPLCRSNQLFSDKDLGMQEPPDQDSAEEHDTCDGVDTCVRRCSSCSSLGQRTGLERSLSL
What are the official names of this protein?
RING-H2 finger protein ATL57, RING-type E3 ubiquitin transferase ATL57.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: URED_NOSP7
Sequence: MICNSQIAEGWHGKLNLVYADRQGATQLIYNQQQAPLKVQRPFYPEAEKVCHSVILHTAGGMVGGDRLSSNIHLQPQAQALITTAAASKIYRSNGLQARQTIQMQVDPGACLEWLPQETILFNDAIYRQDLRVELATGASWLGWEITRFGRSARGEKFLQGEWRSHTEIWQQSVPLWIDRQCLRGSEDIFHSPHGLAGKPIVGSLVWVGGAVSAEIVEKTRSLWNGEGEVGASRLQHGLLCRYRGSSTSEVRNWFIDVWQLLRVSFLNRGNCIPRVWQV
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNF7_RHIML
Sequence: MNAHNMRGPPGDLAKVVPGSRSGWNEGSRCRQADKGDGQCRNGGRDASEHVEARALFLNSNISSKARFSLRTPRVVPSSRCRRRRADAEARRRTAHARHDTNLRTGERCPNESPLLAAILADATNLGLSRRAAASQGVTATNSPGRRMPLSGSFHPIAHKQLVAAAYASNAVSMDGDIQQDNLNGFLTSEPAARGCGQGRRLASSRPCMMASFHRNQSFARAHRRPTPTRPD
What are the official names of this protein?
Uncharacterized protein ORF7 in nfe locus, ORFB.
Protein: MGR3L_YEAST
Sequence: MWKYLHRSVKNEGTVERLTNLNLFTNHRFKFYSTLKEQSFWRIPFKRRSKLQKWVLSTGIVSFIAFNIWWVYWPHHTFPKPVAKILRKGLHSEIKKEGANYQKSLEYYLEALEECKAENVDLLSDEYTGIEIKIGEMYEKLHMYNDATALYGDMLKKFYNELSKTTDKSTKRKFFLLKRDLQILVRFNEINKDSETNATLLIMHLLLAQREFLENSPEFKNVLSKSELLNNQQLDWKNFKGLPFIGKSKPDYQMHLNSKRKQELKIKEPESEQCVFMKELLTARDLYTRYCLNRSNLSGALNSKITTLEWMLLADSPLDDILLAQAELGSIFYLNSEKFEGSLYAIDNEPYKKSEPLELIRSRLQENQNSCLQYSADCYKSIISFANENQYPKVAMESEMDQRILKALSLAHYGIGVINLHKGRLRASKKELKKAIRISEMIRFNELIEEAQRELKKVDGTPI
What are the official names of this protein?
Protein MRG3-like.
What is the protein family that this protein belongs to?
Belongs to the MGR3 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NS3B_BC133
Sequence: MDYVSLLNQFWQKQIKSYKETPSQYHYLYPPRFFYKPVLGNLQHPTKWCCTIKFYEYSAQATECTKASAKQDAARLICEQLQAAGLLNGMELRFRSSASDIFGQNRYDASKSYFFSKTA
What is the function of this protein?
Induces host cell G0/G1 arrest and apoptosis.
What are the official names of this protein?
Non-structural protein 3b, ns3b, Accessory protein 3b.
What are the subcellular locations of this protein?
Host nucleus, host nucleolus. Host mitochondrion.
Protein: RS19_PHEZH
Sequence: MTRSVWKGPFVDGYLLKKAEAAQSSGRKDVIKTWSRRSTIMPQFVGLTFGVHNGHKHVPVLISEDMVGMKLGEFAPTRFFPGHAADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: RAVR2_MOUSE
Sequence: MAARGGGAGGAGSGSGPSAGTAGEAAEPALRPGEVAALHPQEVAARLQRMRRELSNRRKILVKNLPQDSSSQEVHELLQDYELKYCYVDRNKRTAFVTLLNGEQAQSAIQRFHQFSFRGRELTVQLQPTDALLCITNLPISFTLEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFAAKARLELLGRQMGASALFAQWMDVNLLASELIHSKCLCIDKLPSDYSDSEELLQLFSGIHKPVFCQLAQDEGSHGGGFAVVEYSTAEHAEEVQQVADGITIKGSQVQLSFCAPGAPGRSTLAVLIAAQRAMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQLCGRAMKPVLGVAPSLSHLLSPSLPSAILHFSKAQQSSAVGNTSSLILQNLSPLPLIQQQLMKFDNAHTNNKPGLLGEPPAMVLQPALAIGPPLPLKTDLGHHGEAHKTSNLIPPQTTLAAGLGMLPFFSNQLPAGQAGPGRGTTQEKQSASVSISEASFSGSQHYLQTFPGLPAGGPLTGNQKTPQSQPKGTEVASKNQTSLLGEPPKEIRLSKNPYLNLASVLPSVCLSTAGKGMPPKTGIASNILDAISQGSESQHALEKCIAYSPSIEDYAQASSLRNEKRGSSYLISAPEGGPVELAGQHPQDTGVSYTETYLKKKRVY
What is the function of this protein?
May bind single-stranded nucleic acids.
What are the official names of this protein?
Ribonucleoprotein PTB-binding 2, Protein raver-2.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=May shuttle between the nucleus and the cytoplasm.
Protein: Y1354_XANCB
Sequence: MIVSGLSGSGKSVALKTFEDLDYYCSDNLPVELLPDFVRSRLRGNPLGDQRLAVGIDVRSRSDLTQLAQWRQAAQEYGIEARLLFFEASDEALLKRYADTRRRHPLSQLGLALPEAITRERELTAPLRAQADAIIDTSALNVHQLRRRVVTEFALGNSDRLSLLFESFAYKRGVPAEADFVFDARVLPNPHWDPELRPLTGRDAGVRDYLDKEPDVIRYSAQIVDLLDTWLPRLRNDTRSYVTIAFGCTGGKHRSVYLAERMARHAREQGWPEVATFHREQD
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein xcc-b100_1354.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: NUOB1_CHLSY
Sequence: MAEIDPTQLELERQGILLTTVNRFYNWGRRSSIWPMAFGLACCAIEMMAFGLSRYDVARFGAELFRASPRQADLMIVAGTVTKKMAPQVVRLYNQMAEPRYVISMGACATSGGPFRDGYNVLRGIDLLIPVDVYVPGCPPRPEALLHALMTLQEQIDRQKLGRVRWYGSGDKPQTGDFPVPTFGAKGLEIDGKLVDPVGGLPLLSPYTSPSHGEHRSGQIEHPEVVRQFPIMDPEVELENALKARGIAPEIAADDLKRSVVNDA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ENGB_PHOPR
Sequence: MTELTVNQPLNYRNTGFITSAPDIRHLPQDTGVEIAFAGRSNAGKSSALNRITDQKGLARTSKTPGRTQLINMFEVTQGCNLIDLPGYGFAQVPLELKIKWQKALGEYLQKRECLKGLVVLMDIRHPMKDLDQQMIFWAIESRLPVLVLLTKADKMKSGARKAQLLKVRESSKSFGGDVQIELFSSLKGIGLDQVRRKLDTWFGPELERQLMLAAAENGETYTGESLSDKSDD
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: ULAF_SALPA
Sequence: MQKLKQQVFDANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSGVAYETMKVDDMVVVDMDGKVVEGRYRPSSDTATHLALYQRYPSLGGVVHTHSTHATAWAQAGMAIPALGTTHADYFFGDIPCTRALSEEEVQGEYELNTGKVIIETLGEVEPLHTPGIVVYQHGPFAWGKDAHDAVHNAVVMEEVARMAWIARGINPGLNPIDDYLMNKHFMRKHGPNAYYGQK
What is the function of this protein?
Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate.  Is involved in the anaerobic L-ascorbate utilization.
What are the official names of this protein?
L-ribulose-5-phosphate 4-epimerase UlaF, L-ascorbate utilization protein F, Phosphoribulose isomerase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: HOA_BACC3
Sequence: MRRNSERPVRITEVCLRDGSHVMKHQFTEEQVRFVTRALDEAGMHYIEVSHGDGLGGSTLQYGKSLVNEMKLIEAAVDECKQAQIAVLLIPGIGTIHELKQAANIGAKLVRVATHVTEADVSAQHIQFARELGMEVCGFLMMAHSASVEKLVEQGKLMESYGAEAVYVTDSAGALLPHEVRERIRALRQSLNIEIGFHGHNNLSVAVANTITAIEEGATRIDGSVRCLGAGAGNAQTEVLLAVLDRMGYKLDIDLYKMMDVAEEVVAPLLPVPQEIQKGSLVMGYAGVYSSFLLHAERAAQRFNVDARDILIELGKRKVVGGQEDMILDVAAELAKIKMEV
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: HEM6_AROAE
Sequence: MGAPDSRVVRQHLLDLQSGIVAVLERFDGGRFREDAWQRPAGGGGITRVIEEGRFFERGGVNFSHVIGGAMPASATAHRPDLAGRTFEAMGVSLVLHPRNPYCPTVHMNVRFFIASHPEAAVPPPAAAPVWWFGGGMDLTPYYPYEEDVRNFHRACRAAVLPWGGEPEYRRLKEWCDRYFFLKHRNEPRGVGGLFFDDLGADGKTDFDAAFGLARSVGDAFLDAYLPIIERRRDVAYGERERDFQAYRRGRYVEFNLVFDRGTLFGLQSGGRTESILMSLPPVVKWRYDWQPEPGSAEARLYDEFLAPRDW
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, CPO, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS5_CAEEL
Sequence: MADNWGSENVVADAAPATEAPEVALFGKWSLQSVNVSDISLVDYIPVKEKSAKYLPHSAGRFQVRRFRKAACPIVERLANSLMMHGRNNGKKLMTVRIVKHAFEIIYLLTGENPVQVLVNAVINSGPREDSTRIGRAGTVRRQAVDVAPLRRVNQAIWLLCTGAREAAFRNVKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSNR
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (By similarity).  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (By similarity).
What are the official names of this protein?
40S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: FABZ_MARMS
Sequence: MMDVNEIRQYLPHRYPFLLVDRIVEINLNDSIIAYKNVTINEPFFNGHFPNHPVMPGVLIIEAMAQAAGVLGFKSMDKKPEDGSIYYFVGADNARFKRPVVPGDRLQLEAKIIAEKRGIWKFECRATVDGQLACSATIMCADRKI
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CMAS2_MYCLE
Sequence: MVPSQSHPAKTPRKQLKPPIEAVQSHYDRSNEFFKLWLDPSMTYSCAYFERPDLTLEEAQRAKRDLALSKLGLEPGMTLLDIGCGWGSTMLHAIEKYDVNVIGLTLSANQLAHNKLKFAEIDHTRTDRTKDVRLQGWEQFDEPVDRIISLGAFEHFADGAGDAGFERYDSFFKMCYDVLPDDGRMLLHTIIVPDAKETKELGLTTPMSLLRFIKFILTEIFPGGRLPKISQVDHYSSNAGFTVERYHRIGSHYVPTLNAWAAALEAHKDEAIALQGRQIYDTYMHYLTGCSDLFRDRYTDVCQFTLVK
What is the function of this protein?
Catalyzes the formation of trans cyclopropanated ketomycolate or methoxymycolate through the conversion of a double bond to a cyclopropane ring at the proximal position of an oxygenated mycolic acid via the transfer of a methylene group from S-adenosyl-L-methionine.  In the absence of MmaA2, CmaA2 has a non-specific cis-cyclopropanating activity and is able to catalyze the conversion of a double bond to a cis cyclopropane ring at the distal position of an alpha mycolic acid.  Cyclopropanated mycolic acids are key factors participating in cell envelope permeability, host immunomodulation and persistence (By similarity).
What are the official names of this protein?
Cyclopropane mycolic acid synthase 2, CMAS, Cyclopropane-fatty-acyl-phospholipid synthase, CFA synthase, Cyclopropane fatty acid synthase, Mycolic acid methyltransferase, MA-MT, S-adenosylmethionine-dependent methyltransferase, AdoMet-MT, SAM-MT.
What is the protein family that this protein belongs to?
Belongs to the CFA/CMAS family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_ECO5E
Sequence: MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: MDTA_ECO8A
Sequence: MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQQSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPEEKATSREYAKKGARS
What is the function of this protein?
The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate.
What are the official names of this protein?
Multidrug resistance protein MdtA, Multidrug transporter MdtA.
What is the protein family that this protein belongs to?
Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RU2A_DEBHA
Sequence: MRLTSQVLSDAPTIINPEKQVTLSLRSLKIPYLENLGITKDTYEVIDLTDNELIELSNFPRLKNLKVLLVGNNNITGINDDKLPNNLPHLQSISFIHNNISKFSDVRILCRFKNLSNITFIENPITDSPNYRYFIVWLIPTLKVLDFSKVKQKELVKAKELFGESIDDPSELALSMLEDISTTESRKNQISSKDIRNLQDVGKKLTDEDKAKLLQELETADSVEDIERIERALHNGHM
What is the function of this protein?
Involved in pre-mRNA splicing.
What are the official names of this protein?
U2 small nuclear ribonucleoprotein A', U2 snRNP A'.
What is the protein family that this protein belongs to?
Belongs to the U2 small nuclear ribonucleoprotein A family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ENY2A_SALSA
Sequence: MSKDSKMRATINQKLTEMGERERLKELLRAKLTECGWRDQLKALCKDVIKEKGLEHATVEDLVVEITPKGRVLVPDSVKRELLQRIRAFLAQHAT
What is the function of this protein?
Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes.  The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histones.  The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription.  The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket).  TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery (By similarity).
What are the official names of this protein?
Transcription and mRNA export factor ENY2-1, Enhancer of yellow 2 transcription factor homolog A.
What is the protein family that this protein belongs to?
Belongs to the ENY2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: GUF1_SCHPO
Sequence: MSIFRLSRTFSLETCLKSSSFKIRWRFFSVSYASRKLASEDNKPSIQEVVRGIPQNRVRNWAVIAHIDHGKSTLSDCILKLTGVINEHNFRNQFLDKLEVERRRGITVKAQTCSMIYYYHGQSYLLNLIDTPGHVDFRAEVMHSLAACEGCILLVDASQGIQAQTLSNFYMAFSQNLVIIPVLNKVDLPTADVDRTLIQVQQTFDIPMSKPILVSSKTGKNVEQILPEIIQKIPPPKGSENAPLRCLLIDSWYNSYQGVIGLVRIMEGFIKKGGKVMSVNTGRKYEVQQVGIMYPDMTEVSRLRAGQVGYIIWNMKNIDEAIVGDTYSTIGSNVEALPGFSIPQSMVYVGAFPLDGSDYERLNDNIEQLALNDRAINVQKENSSALGMGWRLGFLGTLHLSVFIDRLKDEYGKELLITSPTVPYRIKYKNGREEVISNPNLFPTNHQGISELLEPTVDATIITPSEYLGDVIKLCESCRGLQKDCTYMSESRCMIKYQLPLAHLVEDFFGRLKGTTSGFATLDYEESDYVPADLVRLSIFMSGKSVDALCSIVHRSLALQRGREWIQRLKPLVPKQLYEVILQAVIDNRVVARESISALRKNVTAKCYGGDVTRKQKLLNKQKEGKKRLKSVGNVSIDKSVFYEFLTKKQSN
What is the function of this protein?
Promotes mitochondrial protein synthesis.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Binds to mitochondrial ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Translation factor guf1, mitochondrial, Elongation factor 4 homolog, EF-4, GTPase guf1, Ribosomal back-translocase.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RAP94_VACCC
Sequence: MDSKETILIEIIPKIKAYLLDANISPKSYDDFISRNKNIFVINLYNVSTITEEDIRLLYTTIEQNIDADDQTLVAIFSYIGYKFEQAVKEEISTSLSFNDKNTTDEMTYNLYDLFFNTLDMYLRQKKISILVNDDVRGDVIVSYKNSDLVSSFNAELEPEIKKIPFNMKNLLPYLEKNLDQLRFSKKYLDFAYLCRHIGIPISKKKYNVRYVFLYKIDGLSIPIIIKDFLDVKYVYLENTGKIYKNSFSEDHNNSLSDWGKVIIPLLKDRHLYSYIFLSSYHLHSYYTDLIARDEPVFVKRKKLDIIEIDEPEAWKRDVRVEFAPCEHQIRLKEAMKVDANYFTKINNFANEFIYYEDGVAYCRVCGINIPIFNLDAADVIKNTVIVSTFNKTIFLSEPYSYFVHSQRFIFNIIMSFDNIMKSQTWVMKYNINRLILNFLIDINSRRQEYEKKFSSEIKRGLFFLRLSANLFESQVSSTELFYVSKMLNLNYIVALVIILNSSADFIVSYMTSKNKTVEESTLKYAISVVIYDFLVKTRICEKGSLDTIVLFTDVYTSIMPEELDLHFQRITLELRKLVSIQRSALEPNYDVESRGEELPLSALKFFDTSTIIVKTMAPVHTCVEQKIVAPTPSVEPTDASLKNFKELTCDEDIKILIRVHDTNATKLVIFPSHLKIEIERKKLIIPLKSLYITNTLKYYYSNSYLYVFRFGDPMPFEEELIDHEHVQYKINCYNILRYHLLPDSDVFVYFSNSLNREALEYAFYIFLSKYVNVKQWIDENITRIKELYMINFNN
What is the function of this protein?
DNA-directed RNA polymerase-associated factor required for the transcription of viral early genes as well as for transcription termination.  Within minutes after virus entry, recruits the core RNA polymerase, the early transcription factor (ETF) and other enzymes needed for transcription initiation, elongation, and termination thereby allowing synthesis of early mRNAs which are extruded through pores in the core particle.  Recruits the multifunctional OPG102 protein, with poly(A) polymerase-stimulatory, cap nucleoside-2'-O-methyltransferase, and transcription elongation activities.  Interacts with nucleoside triphosphatase I/OPG123, a DNA-dependent ATPase required for the termination of early transcripts.  Acts as a transcription termination factor by binding, together with the capping enzyme/VTF, to the termination motif 5'-UUUUUNU-3' in the nascent mRNA.  Involved as well in the packaging of RNA polymerase and other components needed for early transcription in assembling virus particles.
What are the official names of this protein?
RNA polymerase-associated transcription-specificity factor RAP94, Protein H4, RPO-associated protein of 94 kDa.
What is the protein family that this protein belongs to?
Belongs to the poxviridae protein RAP94 family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome.
Protein: DDL_SYNFM
Sequence: MSTEKLTVALLSGGASAEREVSLKSGEQVFNALDKQRYLVLRYDPAHDLTRLAADAEKIDVALIILHGRMGEDGTIQGLLESLGIPYQGSGVLGSAVAMNKILSKQLYIHAGLPVAPHLVADRREPPDLDTVADRLGLPVVVKPEHEGSSIGLSIVRNRDQLAAAVETGWQYDRRCLIEKYVHGIEITGGVLGNDHLQALPLIEIIPGEAYEFFDYKAKYTPGASREICPARLSDTITAKAQEYARKAHQALCCKGYSRTDMIVSGNDIFILETNTIPGMTATSLFPQAAAVAGISFSALLDRLIELALED
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: C81E8_MEDTR
Sequence: MTTFYLSLIISLFFLIITLKVFFNTSRKFKNLPPGPQCLPIIGNLHQLKQPLHHTFHTLSQKYGQIFSLWFGSRLVVVVSSLTIAQECFTKNDIVLANRPHFLTGKYIGYNNTTVAQSPYGDHWRNLRRILSIEILSSHRLNSFLEIRRDEIMRLIQKLAQKSYNGFTEVELRPMFSEMTFNTIMRMVSGKRYYGNDCDVSDVEEARLFRGIIKEVVSLGGANNVGDFLGFLRWFDFDGLEKRLKKISKRTDAFLQGLIDEHRFGKRNSNTMIDHLLTQQQSQPEYYTDQIIKGLMVVMLLAGTDTSSVTIEWAMSNLLNHPEIMKKAKNELDTHIGHDRQVDEHDISKLPYLQSIVYETLRLHAAAPLLVPHLSSEDFSLGGYNIPQNTILMVNAWVIHRDPNLWSDPTCFKPERFEKEGEVNKLLSFGLGRRACPGENLSQRTEGLTLGLLIQCFEWKRIGEEKIDMVEAKGITAGKKTSLNAMCKVRHPLKINDVF
What is the function of this protein?
Probable monooxygenases exhibiting no activity with isoflavones such as formononetin, biochanin A, pseudobaptigenin, daidzein, genistein, isoformononetin and prunetin, or with flavonoids including naringenin, liquiritigenin, apigenin, luteolin, or kaempferol.
What are the official names of this protein?
Cytochrome P450 81E8.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.