PharMolix/UniProtQA huggingface dataset:
Protein: KMO_XANCP
Sequence: MSAAASPRSLTLIGAGLAGCLLAILLSRRGWQITLYERRGDPRIKGYESGRSINLALAERGRHALRQAGAEDAVMAKAVMMRGRMIHPVSGEPQLQRYGRDDSEVIWSIHRAALNVTLLDLAEQAGARVHFYRRLHTVDFDAGYARFIDDRDDQPHEIHFQALVGSDGAGSALRAAMQRKAPVGEHIAFLDHSYKELEIPPRADGGFRIERNALHIWPRGRYMCIALPNDGGTFTVTLFLPNEGMPSFATTRSGDEALALFARDFPDALPLIPQLKEHWEEHPPGLLGTLTRERWHLDGRAVLLGDAAHAMVPFHGQGMNCAFEDCVALAEQLDAHSDLSEAFAAFEAARRDDAAAIQQMALENYLEMRDRVGDAQFLLQRALEQQLQARWPTRFVPHYTMVTFLRTRYAIALARSEIQREILLEATHGHTDLSRIDWVALETVVHARLEPLEGAH
What is the function of this protein?
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn).  Required for synthesis of quinolinic acid.
What are the official names of this protein?
Kynurenine 3-monooxygenase, Kynurenine 3-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
Protein: RIBBA_BACAA
Sequence: MFHRIEEALEDLKQGKVVIVCDDENRENEGDFIALAEYITPETINFMITHGRGLVCVPITEGYAERLQLEPMVSHNTDSHHTAFTVSIDHVSTTTGISAHERATTIQQLLNPASKGADFNRPGHIFPLIAKEGGVLRRAGHTEAAVDLAQLCGAEPAGVICEIINEDGTMARVPDLLQCAKQFDIKMITIEDLIAYRRHHETLVTREVEITLPTDFGTFQAIGYSNSLDTKEHIALVKGDISTGEPVLVRVHSECLTGDVFGSCRCDCGPQLHAALAQIEREGKGVLLYMRQEGRGIGLLNKLRAYKLQEEGFDTVEANEKLGFPADLRDYGIGAQILKDLGLQHLRLLTNNPRKIAGLQGYDLTVTERVPLQMPAKEENKTYLQTKVNKLGHLLNL
What is the function of this protein?
Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
What are the official names of this protein?
Riboflavin biosynthesis protein RibBA.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the GTP cyclohydrolase II family.
Protein: CHEB3_BURTA
Sequence: MTEFSSKERYTMIRVLVIDDSATMRILLKKLIDKNEHMECVGVAPNPVAAQELLRETRPDVITLDIEMPKMNGLDFLDRIMRLMPVAVIMISTLTEAGSESALRALELGAIDFIAKPKLDFAEGVQAYAEEIYRKIETAGRAKVKKLTRDVPPVRMDAEPPAKPLLAEAGKDGRVVAVGASTGGTEAVKELLLSLPADCPPLLIAQHMPEPFMRSLAKRLDLLCAMRVKMAEDGETLRRGCVYIAPGHSNLTIDATAAGYVCRIVRNAGEAQSDSSVDELFRSVAAAAGARGVGIVLTGSGSDGAAGARAMMAAGAFNIAQDAETSVVYSMPDAAIAACGINEVLPLEKIAGKLMELDGA
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 3.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOKC_BACSU
Sequence: MDNRKMLLRQKLKINKQKSLRVTLMSTLPRDMATTIEDCSLITSPELERILDKVQKKWNFELHKNDFAIKYSEHRKEYSWEYEVINHVQQTKLPDEQVYLYLGIEDSPIFLINGNWIIENFNFLWEQINNSDLWIIDFNFKYGVLVSRYGGYLDHDPNPNEIIYAVTEWGI
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YokC.
Protein: QUEA_GEOUR
Sequence: MQLNDFDYYLPTELIAQQPAQNRDASRLMTLDRVNGELNETIISEIAALFRDGDLLVINDTRVIPARLLGKKESGGRVEVFLVRRLLEPGEVWQCLIKASKSPKPGSLIILSEGVVARVLERSELDTWAVSFSPVEGFLDRLERIGSMPLPPYIRRSAGDDDRERYQTVFARAKGAVAAPTAGLHFTDALLQKIRQQGVEIAPLTLHVGLGTFMPVRVDDLKDHRMHREYYFIPEATARAVNARKNDGGRVVALGTTTTRALEHAAAGNGSVQPGEGEADIFICPGYTFKVVDALITNFHLPKSTLLMLVSALAGKDRLFNAYNEAVNRNFRFFSYGDAMFIY
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRAY_BACSU
Sequence: MLEQVILFTILMGFLISVLLSPILIPFLRRLKFGQSIREEGPKSHQKKSGTPTMGGVMIILSIIVTTIVMTQKFSEISPEMVLLLFVTLGYGLLGFLDDYIKVVMKRNLGLTSKQKLIGQIIIAVVFYAVYHYYNFATDIRIPGTDLSFDLGWAYFILVLFMLVGGSNAVNLTDGLDGLLSGTAAIAFGAFAILAWNQSQYDVAIFSVAVVGAVLGFLVFNAHPAKVFMGDTGSLALGGAIVTIAILTKLEILLVIIGGVFVIETLSVILQVISFKTTGKRIFKMSPLHHHYELVGWSEWRVVVTFWAAGLLLAVLGIYIEVWL
What is the function of this protein?
Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
What are the official names of this protein?
Phospho-N-acetylmuramoyl-pentapeptide-transferase, UDP-MurNAc-pentapeptide phosphotransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 4 family. MraY subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NHAA1_SHEDO
Sequence: MQSNKMTKETKNVLQRGLENIHHPVSNFIRAQTTSSLFLLFATIIALWWANSDYAQSYQALIHTQLGFFIGDFELKASLKHIINDGLMVIFFFLLGLEIKREVIAGELAQAKNRRMLIICAMGGMVCPALIYSGFNWSLDSQIGWGIPMATDTAFALGVLTMVRKHIPSSLVAFIVGLAIVDDVGAILVIAIFYTQEISLMHLLSACALIGFLGVANYAGVRQPLFYFIIGVAAWWAMLKSGVHPTVAGVTIALTIPAQPKLASGKWLEKAKSIISAIQNKSKNMDVLGNKGHHEQVLKVRDFAERASTPLRRWEDALDLPVVLFILPLFALANAGVVINLSSFIESVQHPVGLGIISGLILGKLIGISGACWFALKFNIGCLPDKVDLNHVIGASLIAGIGFTMSTFIATLGFGDQDTALHVAKTSILLASVLTAILGLLYLRFVSTKA
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA 1, Sodium/proton antiporter NhaA 1.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IRLD_DICDI
Sequence: MGPKKGKRSHSKNHHHHNNGNNNNNNNSGGGSSSDILYTYSQDTRILLFKVILTQNEEIICMVIQIAYGLPGLPKISDISRDLGILILKLPNRTIRELELFLESKNIYFREDQHINYLNEIPQPTTTTTSPPPPPPPSSISTTTTTTTATAIEIESSSGLTSNITDSTEIQLDSTTTDTKTTSTTSTTTNNSSDSNNNNNNNNNNNSNNILNFPFNCQNKSKQKRPISKEESFNKMVQYNFDLGKIFDEFTREVLLDDLKNDLKIDNIPIDNISISPTPIISPVFQEYDLFLMDSFIILCGQLDNVKLTLEEFKDYYKKYKLLNQYIEDFKDNLINDFLVTVEILASWYIPQKDYSIVKFINCFGEMLDSTIIESFSYIFNKTIKKEDDWSISFIQAALGSNEEFKRQVMCLNDELIQDRYDQSLYSIMHPIKFDNVREFILIYSRDENYFEPQEFWYLICKYDAIAITQHIINNNIAEEDLSKRSGKTYNSNLSENPLEINPLSLLEICSANFSHKIASILFQFYDFKDSMPTRFSLRGVFKPTTTTTTTTTTTTTTTTTIDKDEKDKENNNNNVISQQFQYFRVLDVNCYFNDVIKKRAPIFIDLMTQSNIYLNTEVGEGSDENVDTHESIYSFQNSTEYLAINSNSIHRLKRSSISLLSKVLEFNDRDTLISLLKNLTQGGCTLCKDLIDEKQLLITISRPQYHQSIQILHQNGYTIIPKYQLRDPYIFFAGSKQILQYLLEIHTNSLSETIDIRHWIQAIMSAGQYSSETEFFQYYPKIQELSLRDKYSRTLNILELQYILGHIEGIEFLLEKYLDFTKPYHLDNQELLEIFDVTFVQKKDIRTEESLKAEKDLLEQEENEKKRLKEKRKKEEKEKKKQQNLKQKSLITNNTTTTTTTTPIPITVPIPTQTQTPTQTPTQTPIPTPIPTTPIPTTPIPIPIQLTPTTPKTPKTPKTPKTPTTPKTPITPKTPKNSTLDKQTISTPKTPPPLSVNTTPITPSPPPQTIATTITTTTTTPKTTKTTTTSKIPTLIIELNKYDISIGKFKFSRKDEFIIGRGSNGTLVFKGIWNDRIPVAIKQMHKAFNPLISKEIEVLITLTNKNCNNIVRYIDQEEDDMFVYLGLTLCNGSLQNLVEKDLEINLISTSNNENNNNNKLKNFIGSELRLLELIKDIVYGIQFLHQQGIVHNDLNPRNILIKDDRFIISDLGLSKMEVTSSYSFTMHAPTGQEGFHPAEVLLEKRKTKSVDIFSMGCILFYLMTGGQHPFGDKFFRMANILTDKPILEPLKHNLVACDLISQMISKNESDRPTTENILLHPFFWNHEKKVKFIDASLNLFKDSNGLFTSKLNKLINQFQDTDGVNTTSTPFLSKPWNQLIDPTLIEHITNKQNQLSGGSSIGNNNNNSLTLSGKKFYFYDYSQVKDLVRCIRNTIQHHKEIQRLISQSPSSSNKQEVLDCLESQELVLSYFEEKVPDLLLFLYQKFKKHLDSKSLIYFNDLIIK
What are the official names of this protein?
Probable serine/threonine-protein kinase irlD, Inositol-requiring protein-like protein kinase D.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: UVRC_MYCLE
Sequence: MPDPATYRPATGSIPVEPGVYRFRDPYGRVIYVGKAKSLRSRLASYFADVANLHPRTRQMVTIAAKVEWTVVNTEVEALQLEYNWIKEFDPRFNIRYRDDKSYPVLAVTLGEEFPRLMVYRGPRRKGVRYFGPYSHAWAIRETLDLLTRVFPARTCSPGVFKRHKQIDRPCLLGYIDKCAAPCVGRVGAEQHSQIVADFCDFLSGKTDRYARDLERKMSAAAEQLDFERAARLRDDLFALKRAMEKQAVVFGDGTDADVVAFAYDELEVAVQVFHVRGGRVRGQRGWIVEKSDDPGDTGEEQLVEQFLAQFYGEQAELDFVADESANPVPREVLVPCLPSNADELASWLSGLRGSRVALRVPRRGDKRALAETVQRNAKEELQQHKLKRASDFNSRSAALQNIQDTLGLSYAPLRIECVDISHVQGTDVVGSLVVFEDGLPRKSDYRHFGIRKAAGNGRSDDVASIAEVTRRRFLQHLHDQNDTNLLSPEGKSHRFAYPPNLYVVDGGAPQVNAASTVLEELGIIDVAVIGLAKRLEEVWVPFEPYPVIMPRNSEALFLLQRVRDEAHRFAITYHRSKRSKRMTASALDSVPGLGAHRRKALVTHFGSIARLKDATVEQITAVPGIGVATATAVLEALRPDSSEASE
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYR_LACPL
Sequence: MDYKQLVAAALAPALPDLTQEAILDKIEQPKTSKQGDLAFPTFTLAKTLHKAPQMIASDIVEKVDSSDFEKVVAMGPYVNFFFKKDAFAADILNQVLSNGGHFGDAKLGEAGQVPIDMSSPNIAKPISMGHLRSTVIGNSLANILSKLDYQPVKINHLGDWGTQFGKLITAYKMWGSEAEVKADPINNLLKYYVRFHKEDVDHPEMDDEAREWFKKLENGDEEATHLWSWFRSESLKAFKKIYQRLDIDFDSFKGEAFYNDKMQEVVDILEDKHLLQESQGAEVVDLSKYDLNPALIKKSDGATLYITRDLAAAIYRKRTYDFVQSLYVVGNEQTNHFKQLKAVLTEMGFDWADQIHHIPFGLITSGGKKLSTRSGRVILLDKVLDDAVALAHEQIEAKNPDLPNKDEVADAVGIGAVVFHDLKNERMNSFDFNLEEVVRFEGETGPYVQYAHARAESILRKAGSPEIAATEQTLSDPAAWDTLKLLSEFPATVVRASTEYEPSVIAKYAIHLAKAYNKYYANTKILVEDDELNARLALVKSVSIVLKEALRLLGVKAPDEM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSB_YERPN
Sequence: MSGWRKIYYKLLNLPLKLLVKSKVIPADPVSELGLDPSRPILYVLPYNSKADLLTLRAQCLAQDLPDPLIPLEIDGVQLPSHVFIENGPRVFRYYVPKQESVKLFHDYLDLHRNNPALDIQMLPVSVMFGRSPGREGHGTPHLRVLNGVQKFFAVLWLGRDSFVRFSTTVSLRRMASEHGTDKTIAHKLARVARMHFSRQRLAAVGPSLPARQDLFKKLLASKAIEKAVADEARSKKISHEKAQQNAITLMEEIAANFSYEAVRLSDRVLSWTWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFTRGYSVEYFVEGGRSRTGRLLEPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGAIKEKENLLQMLRGLRKLRNLGQGYVNFGEPLPLTTYLNTHVPQWRDAIDPIEAQRPSWLTPAVNDLANQIMVRINNAAAANAMNLCSTALLASRQRSLTREQLLEQLDCYLQLMRNAPYAKDTTVPDKTPEELLNHALNMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIQHLLILPSLIASMVMYHRRITRTELLHKISMIYPMLKAELFLHYSKEQLPETLDTLIDELARQQLICDKGSELVLNPARIRPLQLLAAGVRETLQRYAITLSLLSATPSINRGALEKESRIMAQRLSVLHGINAPEFFDKAVFSTLVATLREEGYISDSGDAIQEHTLEVYNMLSALMTPEVKLTIESVSMPAETSNQPEAPETPEPEGKTES
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: 080R_IIV3
Sequence: MDNETSTPDIFQWCVSPFSKITLKRSMEQRDIVEFRIDATILRQIFHHGFPDLSFNLMVITTDRKVFLLERTESFHYPRVVERIKRGQECTKLVETLYQAERDAVRRLTAEADIVPLAAVKQDDDRPESIYIFPGGHCNGNEPVLSTLLREFREETTIPLKTTELRFHATKVYGIWIHDFAVGKTFKNFVFPVKINLSSAAIRDRFRETRHTRNPTFVDIGKSHRQSLLDLVIKVQKIMIL
What are the official names of this protein?
Putative hydrolase 080R.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
Protein: HUTU_BRUA4
Sequence: MSNPRHNEREVRSPRGDELNAKSWLTEAPLRMLMNNLDPDVAERPHELVVYGGIGRAARTWDDFDKIVATLKTLNEDETLLVQSGKPVGVFRTHKDAPRVLIANSNLVPHWATWDHFNELDKKGLAMYGQMTAGSWIYIGAQGIVQGTYETFVEAGRQHYDGNLKGKWILTGGLGGMGGAQPLAAVMAGACCLAVECDETRADFRLRTRYVDEKTHSLDEALAKIDEWTKAGEAKSIALIGNAAEIYPELVKRGVRPDIVTDQTSAHDPVHGYLPIGWTVAEWRAKQESDPKGVAKAARASMKVQVQAMLDFWNAGIPTVDYGNNIRQMALEEGLENAFDFPGFVPAYIRPLFCRGVGPFRWAALSGDPEDIAKTDAKVKELLPDNKHLHNWLDMAKERIEFQGLPARICWVGLGDRHRLGLAFNEMVRNGELKAPIVIGRDHLDSGSVASPNRETEAMKDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHSGMVICCDGTEDADQRIGRVLWNDPATGVMRHADAGYDIALDWAKQQGLRLPAILGN
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS11_STRZT
Sequence: MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSSAGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAGLEVTAIRDVTPVPHNGARPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: PYRG_METHJ
Sequence: MKYIFVTGGVMSGLGKGITAASIGRLLKNRGYQVTAVKIDPYLNIDAGTMNPAQHGEVFVLHDGGEVDLDLGNYERFLDIELNSSHNITTGKVYRMVIDKERRGDYLGQTVQIIPHITDQIKDCIRSAAEEKVFDGKPADICIVEVGGTVGDIESMPFLEAVRQMRSELATADRALVHVTLMPSDSMGDLKTKPTQHSIKALRELGIFTDIIVGRSERPLNSHTKKKLSSLCDIPQNGIISAATAPDIYQVPMELEKEGMADVLCQLLQLRKDGADPEWYRIVTREYTHRITIGIVSKYGKEDVYLSIKEALRHAGRKLSTEVSIRWLDAERVEPADLRECDGVLIPGGFGVRGIEGKINAIRLCREERIPLLGLCLGFQLSVVEFARNVLGIADACSSECGDGTAVITILPEQEGVENLGGTMRLGDCPVEIKSGTIAYKLYRQHEIIERHRHRYEVDPAYISRLEDAGLIFSGRNGNRMEIAEIEDHPFFFATQFHPEFRSRPTSPSPPFLGFVEACLKNRGKGE
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: ERBB_AVIER
Sequence: MKCAHFIDGPHCVKACPAGVLGENDTLVRKYADANAVCQLCHPNCTRGCKGPGLEGCPNGSKTPSIAAGVVGGLLCLVVVGLGIGLYLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTIYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDMEDIVDADEYLVPHQGFFNSPSTSRTPLLSSLSATSNNSATNCIDRNGQGHPVREDSFVQRYSSDPTGNFLEESIDDGFLPAPEYVNQLMPKKPSTAMVQNQIYNFISLTAISKLPMDSRYQNSHSTAVDNPEYLNTNQSPLAKTVFESSPYWIQSGNHQINLDNPDYQQDFLPTSCS
What is the function of this protein?
The v-erbB oncogene transforms avian fibroblasts and erythroblasts in culture and induces sarcomas and erythroleukemias in chickens.  It is a truncated and mutated version of the receptor for epidermal growth factor.
What are the official names of this protein?
Tyrosine-protein kinase transforming protein erbB.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
Protein: CLL4_ARATH
Sequence: MKTTPGLRIFKPIIPHTPKPDSRIYVEDAWTMLKPAIRAIFLDEPQDFACSGLFNAVNKSWCEKSSGEALYKLILEECEIYISAAIQSLESQCDTDPSLFLSLLEKCWLDFRRKLQFLCSIAGGEGQTVGPHSVWDLGSELSPKHLFSAQKVRDKLLSIILQLIRDQRSFMSVDMTQLKNTTRPVMSVHMTQLNNLRGLFYGQSLYKSPFFKKPFIDCAVEFYSAEAMQFKEQSDIPLYLKRVEYVA
What are the official names of this protein?
Putative cullin-like protein 4.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: HPCH_SALPK
Sequence: MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEARNAVAATRYPPAGIRGVGSALARASRWNRIPDYLHLANDAMCVLVQIETREAMSNLASILDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEALAKRYLELGALFVAVGVDTTLLARGAEALAARFGAEKNLSGASGVY
What is the function of this protein?
Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde.
What are the official names of this protein?
4-hydroxy-2-oxo-heptane-1,7-dioate aldolase, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, HHED aldolase, 4-hydroxy-2-ketoheptane-1,7-dioate aldolase, HKHD aldolase.
What is the protein family that this protein belongs to?
Belongs to the HpcH/HpaI aldolase family.
Protein: YL279_MIMIV
Sequence: MKSKIYFKFTTEKDEIDGVYKDGLNIYKTSNTITNISSDNKKEGITYLDPSKSARCLYRDAKYLRIVRLHKDTVSVKQDYLNDNGRFWADKLYLGKRFELSDPFTIMYMIKMGYNVRERDDYMLEWACAGNFTEVARYLLKIGANPGTNKYACFESAVRNGNYDMVKLLLENIPGSDKFYYKMLEVFKNKSRYCGPEISKLFFNYVRDCDIDYIIRHDTQKLYVLEDTEFVKSLVGRGLGIGKFIDRTEPKFDKYYLECVVRGFLDTMKYFDTIDTTIVTRNQQQLIEKAVLSKNLDVFKYLEQNIDVGPMIDDLILKCMKIDLFVFVKYMIEKYNVINVLDTNKLIENISLCCNMEMIEYMTNLTGISIPETQGLLTNACQYNNSELVKYLLEKGANVNEFNGKPLREAIKNNNKDIIKNLMDYSPDISLDNYAAIRESFATFPEIAKKLAVGISIEKLHEIIFDQKIS
What are the official names of this protein?
Putative ankyrin repeat protein L279.
Protein: VLN2_ORYSJ
Sequence: MSSAKPVLDPAFQGVGQKPGTEIWRIQDFKPVPLPKADYGKFYNGDSYIVLQTTCSKGGGAYLFDIHFWIGKDSSQDEAGTAAIKTVELDTMLGGRAVQHRELQGYESDKFLSYFKPCIIPLEGGFASGFKTPEEDKFETRLYICKGKRAIRVKEVPFARSSLNHDDVFILDTEKKIYQFNGANSNIQERAKALEAIQHLKETYHNGVCDVAIVDDGKLQAESDSGEFWVLFGGFAPIGKKAICDDDVVLETTAPKLYSINNGQLKLEDTVLTKSILENNKCFLVDCGSDLFIWVGRLTQVEERKAASAAVEEFIATQNRPKTTRVTRVIQGYENHTFKSKFESWPVNSAGSAGAEEGRGKVAALLKQQGVDIKGASKSSAPVDEEVPPLLEGDGKLEVYCVNGSAKTALPKEELGKFYSGDCYIVLYTYHSGDKREEFYLTYWIGKDSIPEDQEMAFQTANSIWNSLKGRPILGRIYQGKEPPQFIALFQPMVILKGGISSGYQKFVEEKGLKDETYSGDGIALFRISGTSIHNNKVLQVDAVSSNLSPTDCFVLQSGNSMFTWIGNASSYEQQQWAAKVAEFLKPGVAVKHCKEGTESSAFWFALGGKQNYTSRNATHDVVREPHLYTFSLRNGKLEVTEIFNFSQDDLLTEDMMVLDTHGEVFVWMGQCVDAKEKQKAFEIGQKYAEHAAAFESLSPDVPLYKVVEGNEPCFFRTYFSWDNTRSVIHGNSFQKKLSLLFGMRSESGSKSSGDGGPTQRASALAALSSAFNPSSQKNKGNDRPKSSDGGPTQRASAMAALTSAFNPSAKPKSPPQRAGQGSQRAAAVAALSNVLTAEGSSQSPRIGDADTAELTPSAASPLSEGASEFSADKDAPGDGALSEGGRTEPDVSVEQTANENGGETTFSYDRLISKSTNPVRGIDYKRRETYLSDSEFQTVFGITKEEFYQQPGWKQELQKRKHDLF
What is the function of this protein?
Ca(2+)-regulated actin-binding protein (By similarity).  Binds actin microfilaments (MFs).  Involved in actin filament bundling, severing and capping.  Caps the barbed end of actin filaments and is able to sever them in a calcium-dependent manner.  May regulate cell expansion in developing organs.  Required for the regulation of plant architecture via the modulation of polar auxin transport and root gravitropism (PubMed:26486445).
What are the official names of this protein?
Villin-2.
What is the protein family that this protein belongs to?
Belongs to the villin/gelsolin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: THIO_CHLAA
Sequence: MAKPIEVHDSDFAEKVLKSKTPVVVDFWAPWCGPCRVIAPILDKLAGEYAGRLTIAKVNTDDNVQYASQLGIQGIPTLVIFKDGREVGRLVGARPEAMYREIFDKVLAMA
What is the function of this protein?
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
What are the official names of this protein?
Thioredoxin, Trx.
What is the protein family that this protein belongs to?
Belongs to the thioredoxin family.
Protein: NEP1_CAEEL
Sequence: MSHEYDTVAPPNAKRMKTDNQLEDKKILYVVLEGCSLETAKVGGEYAILSSDKHANFLRKQKKDPADYRPDILHQCLLNLLDSPLNRAGKLRVFFRTSKNVLVDVSPQCRIPRTFDRFCGLMVQLLHKLSIRAAETTQKLMSVVKNPVSNHLPVGSRKMLMSFNVPELTMANKLVAPETDEPLVLIIGGIARGKIVVDYNDSETKISNYPLSAALTCAKVTSGLEEIWGII
What is the function of this protein?
S-adenosyl-L-methionine-dependent pseudouridine N(1)-methyltransferase that methylates a pseudouridine in 18S rRNA.  Involved the biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.  Has also an essential role in 40S ribosomal subunit biogenesis independent on its methyltransferase activity, facilitating the incorporation of ribosomal protein S19 during the formation of pre-ribosomes.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase nep-1, 18S rRNA (pseudouridine-N1)-methyltransferase, Ribosome biogenesis protein nep-1.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: GDX_KLEOX
Sequence: MSWIVLLIAGLLEVVWAIGLKYTHGFTRLTPSIITIAAMIVSIAMLSWAMRTLPVGTAYAVWTGIGAVGAAITGILLLGESASPARLLSLGLIVAGIIGLKLSTH
What is the function of this protein?
Guanidinium ion exporter.  Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons.
What are the official names of this protein?
Guanidinium exporter.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. Gdx/SugE subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PLF4_BOVIN
Sequence: ESSFPATFVPLPADSEGGEDEDLQCVCLKTTSGINPRHISSLEVIGAGTHCPSPQLLATKKTGRKICLDQQRPLYKKILKKLLDGDES
What is the function of this protein?
Released during platelet aggregation.  Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.  Chemotactic for neutrophils and monocytes.  Inhibits endothelial cell proliferation.
What are the official names of this protein?
Platelet factor 4, PF-4, C-X-C motif chemokine 4.
What is the protein family that this protein belongs to?
Belongs to the intercrine alpha (chemokine CxC) family.
What are the subcellular locations of this protein?
Secreted.
Protein: DER_STAA2
Sequence: MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYSSGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEMVAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVVSHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEYSYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDKRVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERTRLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEPPTFVVFVNDVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: BIOD_STAEQ
Sequence: MNIFVTGTNTDIGKTYVTKYLYKALRTRGYRVCIFKPFQTEEIGGGRYPDLEIYKNECDLDYDVTSLYTFKDPVSPHLAFKIERHQQLNHQTMIDKLESLKAQFDMILIEGAGGIAVPIYEYSDHFYMTTDLIKDTSDFIVSVLPSKLGAINDAIVHQKYIDHQELPPNVLIMNNYTDSAIEQDNLHTIEKLIHKSVYTLGHQATQESFSEAFIQRIIGGSNG
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCTA_BORA1
Sequence: MIEVDQSAGAPVRKHKFYQILYVQVLVAIVIGVLLGYFKPDLGEAMKPLGDGFIKLVKMIIAPVIFLTVTTGIAAMSDLKKVGRVAGKAMVYFLVFSTLALIIGMVVSHIVQPGAGLHIDPASLDQKSVAGYVTKAHDSTITGFLLNIIPATMLSPFVGGDILQVLFVAVLFGLSLAMVGPRAQPITDFFNALSAPVFKLVAILMKAAPIGAFGAMAFTIGKYGIKSIVNLAMLVGTFYATSVLFVVVVLGMVARYNGFSIIKLVRYIREELLLVLGTSSSEAALPTLMEKMERAGCSKSVVGLVVPTGYSFNLDGTNIYMTMAALFIAQACDIPLSLGDQILLLLVAMLSSKGAAGVTGAGFITLAATLSVVPTVPVAGMALILGVDRFMSECRALTNLVGNATASIVVARWEGELDKTALHVALNSDGELPSTDPTSPARQGH
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.