PharMolix/UniProtQA huggingface dataset:
Protein: DSE_HUMAN
Sequence: MRTHTRGAPSVFFIYLLCFVSAYITDENPEVMIPFTNANYDSHPMLYFSRAEVAELQLRAASSHEHIAARLTEAVHTMLSSPLEYLPPWDPKDYSARWNEIFGNNLGALAMFCVLYPENIEARDMAKDYMERMAAQPSWLVKDAPWDEVPLAHSLVGFATAYDFLYNYLSKTQQEKFLEVIANASGYMYETSYRRGWGFQYLHNHQPTNCMALLTGSLVLMNQGYLQEAYLWTKQVLTIMEKSLVLLREVTDGSLYEGVAYGSYTTRSLFQYMFLVQRHFNINHFGHPWLKQHFAFMYRTILPGFQRTVAIADSNYNWFYGPESQLVFLDKFVMRNGSGNWLADQIRRNRVVEGPGTPSKGQRWCTLHTEFLWYDGSLKSVPPPDFGTPTLHYFEDWGVVTYGSALPAEINRSFLSFKSGKLGGRAIYDIVHRNKYKDWIKGWRNFNAGHEHPDQNSFTFAPNGVPFITEALYGPKYTFFNNVLMFSPAVSKSCFSPWVGQVTEDCSSKWSKYKHDLAASCQGRVVAAEEKNGVVFIRGEGVGAYNPQLNLKNVQRNLILLHPQLLLLVDQIHLGEESPLETAASFFHNVDVPFEETVVDGVHGAFIRQRDGLYKMYWMDDTGYSEKATFASVTYPRGYPYNGTNYVNVTMHLRSPITRAAYLFIGPSIDVQSFTVHGDSQQLDVFIATSKHAYATYLWTGEATGQSAFAQVIADRHKILFDRNSAIKSSIVPEVKDYAAIVEQNLQHFKPVFQLLEKQILSRVRNTASFRKTAERLLRFSDKRQTEEAIDRIFAISQQQQQQSKSKKNRRAGKRYKFVDAVPDIFAQIEVNEKKIRQKAQILAQKELPIDEDEEMKDLLDFADVTYEKHKNGGLIKGRFGQARMVTTTHSRAPSLSASYTRLFLILNIAIFFVMLAMQLTYFQRAQSLHGQRCLYAVLLIDSCILLWLYSSCSQSQC
What is the function of this protein?
Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues.  Plays an important role in the biosynthesis of the glycosaminoglycan/mucopolysaccharide dermatan sulfate.
What are the official names of this protein?
Dermatan-sulfate epimerase, DS epimerase, Chondroitin-glucuronate 5-epimerase, Squamous cell carcinoma antigen recognized by T-cells 2, SART-2.
What is the protein family that this protein belongs to?
Belongs to the dermatan-sulfate isomerase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Microsome membrane; Multi- pass membrane protein.
Protein: MURC_PHOV8
Sequence: MDVNTLKSVYFIGAGGIGMSALVRYFLSKGKKVGGYDRTPSELTEKLIEEGAAIHYEESTELITDAFRDPATTLVVYTPAVPDTHKEFTYFRENGFEIHKRSQVLGMLTHAGKGLCVAGTHGKTTTSTMTAHLLHQSHVGCNAFLGGISKNYGTNLLLSDSSEYMVIEADEFDRSFHWLSPYISVITATDPDHLDIYGTKEAYLESFRKYTSLIQPGGALIVRKGIELQPALQNGVKLYTYSQEEGDFHAENIRIGNGEIFFDYVSPLGNIPNIQLGVPVSINIENGVAAMALAQMSGLTDEEIKRGMASFRGVDRRFDFKIKNDKVVFLSDYAHHPSEIKQSILSMRALYRDKKLTAVFQPHLYTRTRDFYKDFADSLSLLDEVILVDIYPAREQPIPGVTSKLIYDHLRPGIEKSMCKKEEILDVLSKKDIEVLITLGAGDIDNYVPQICGLLNKK
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_RHOCS
Sequence: MANHKSAEKRIRQIKKRTEINRARISRIRTFVKKVELAIASGDKAAANEAFREAQPELMRGATKGVLHRNTVSRKLSRLNQRIKALGA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: RS19_CLOBB
Sequence: MSRSTKKAPFVHEGLLKKIEEMNASGDKKVVKTWSRSSTIYPQMIGHTIAVHDGRKHVPVYLSEDMVGHKLGEFVLTRTYRGHVADKTSKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: AP4S1_HUMAN
Sequence: MIKFFLMVNKQGQTRLSKYYEHVDINKRTLLETEVIKSCLSRSNEQCSFIEYKDFKLIYRQYAALFIVVGVNDTENEMAIYEFIHNFVEVLDEYFSRVSELDIMFNLDKVHIILDEMVLNGCIVETNRARILAPLLILDKMSES
What is the function of this protein?
Component of the adaptor protein complex 4 (AP-4).  Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection.  They control the vesicular transport of proteins in different trafficking pathways (PubMed:10066790, PubMed:10436028).  AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.  It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons.  AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (Probable).
What are the official names of this protein?
AP-4 complex subunit sigma-1, AP-4 adaptor complex subunit sigma-1, Adaptor-related protein complex 4 subunit sigma-1, Sigma-1 subunit of AP-4, Sigma-4-adaptin, Sigma4-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein.
Protein: RL14E_METS5
Sequence: MAIIEVGRICVKLSGREAGSKCVIVDIIDNNFVLVTGPKSISGVKRRRVNISHLEPTDKTVEIGKGASDQEVEAKLKEQGLVDFMKEKVKVKIPVI
What are the official names of this protein?
50S ribosomal protein L14e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL14 family.
Protein: FABP2_CAEEL
Sequence: MSSKFLILLAFCGATLVAAEQLPEKFYGTFDLDHSENFDEYLTAKGYGWFTRKLVTFATFKKVFAKNANKNLFDYSNLTSKKDVFYKNVQIGSKFEGEGLDNTKHEVTFTLKDGHLFEHHKPLEEGESKEETYEYYFDGDFLIQKMSFNNIEGRRFYKRLP
What is the function of this protein?
May play a role in sequestering potentially toxic fatty acids and their peroxidation products, or it may be involved in the maintenance of the impermeable lipid layer of the eggshell.
What are the official names of this protein?
Fatty acid-binding protein homolog 2, Lipid-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Secreted. Note=From muscle into the perienteric fluid.
Protein: MTNC_STRM5
Sequence: MQPRVILTDIEGTTSSISFVKNVLFPYARKALPAFVAEHGQQPEVRRWLDAVATEIGGACQDSLVAETLQGWIDQDRKHTALKALQGLIWDEGYRRGDYTAHFYPEVAPVLKGWHASGLPLYVYSSGSVPAQKLFFGFSDAGDLSPLVSGWFDTEIGGKREADSYRRIVQAIDVPAGEILFLSDVVEELDAAREAGLQTRLIDRLDDYPLPRTGQAANGHERVENFQQIQL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: YDJB_BACSU
Sequence: MLNIKSDRIMTSDPQKFTVDGVRFFQQYLNKIRPDAMEIDNLIINSDIIKEDLIVHVSKMIDRLALYDLHRKRSIDKHFSAAFTVDINDREEFYSANIADVSIDLNESSGV
What are the official names of this protein?
Uncharacterized protein YdjB.
Protein: POLG_BECN1
Sequence: MAPVVSRDRHRHKIPKPHQPAPPHRCTVWCPEDCGWYVGRCSCPKSCQREGWDDFFVADKVKPPSYVASKTSVADVVDWLLEEDPATDGPSEFDLTQFFQAYTDKSHQIHRDYAPDQLAQALDMAYILSVDPPDIKLPEYEATRFTHDTSYKGKLPRWLRVYGFKSRELAKKAITNIKGGAHWAKGLFKQAWDTLPGWSEVEAYFKAFFAGIITGVEDALSKSPSSVWTSLKLTPLLYIWRNINECSDIPVILGAFWATLELYNIPSKVYDLVSTALGPMVQDLARRVINIIKGDGNGPKQEGGRPSFSIPGVLLATFLSAIILGSMPSDGIIKKVLRGCATAAGLVGGFNAVKSIITTVQGASACKDVKKLASQLMCVTTMAATVSTRGERQVLASMLNDLNESVRERLVDPAFAALVPQLSAMSSKIMELSTINAAALSAARKRVPAKIVVLCGPPGHGKSVAAHKLAKMLNPNEPSIWNPFSDHHDEYTAEDVVIIDETPAEPGQWVEDLIAMGSNSPFVPNYDRVENKTRCFDSKYVLITTNHNPLINPTHSRAAALARRLTWVYVNSPDVADFLRQHPGVAPPATLFKADCSHLNFDIHPYNSIGTTAVVGHNGTTPLPRAKRTSLEGLCKHIKDLPDREGPPDGVPERMVLVAPDKGTARFVEAVINTYHNSGLVAQPAAWDTTPQKYQLAVTWQGSTSSVVGQRWDCNPQTPFVAPHFTRNMFKRVLGTEVPEYHLLAYACRITSSSLGDKSLPVPNPTVVINDPSPTRLALALMRHLKNPIASGLRVVWDLFRGCATGPKRLFTWALSQEWNPMPVTTAFTFPAGTVILHTAGGVRVVVLPPGPQFGLTEVTHLADHSGQDDPVVPDMFGQTWTELLWRLLKVIGTFLANYGVAIAGLTLSIAAFKTANKSTRNDRQGWLSGSGVALSDEEYDEWMKYSKKKGKKINADEFLQLRHRAAMGNDDDDARDYRSFYTAYQLGREGNNCEDLPLHPAVGPTTGGGYYVHIGNGVGITLKHVASGEDVIKELGNDLVKIRARHHKMGDPAMVVGEGAPVKFVTGHLVVDARNESVVFDQTRLSVVRVKVPGLETQRGYCGLPYVNSAGHVVGLHQGSYGVGDKVFTPITDAPAASPDTIMWRGLECTRSDIVTHLPHGTKYSISPGMREEAHKCTHQPASLGRNDPRCNQTQVAMVVKALTPYTSAPAIEKLDPCMVAAITEVRTAIQSLTPKGGFRPLTFAAAWQSLDLSTSAGALAPGKTKRDLCDPDTGMPAGKYREMLLAAWSRAGTGTPLDHTYIVALKDELRPVEKVAEGKRRLIWGADARVALIASAALTPVANALKTVTNLLPIQVGVDPSSANCVSSWVGRLQRHDHCLELDYSKWDSTMSPVIINIAIDILCNTCGSDSLRMAVAQTLKSRPTALVEGVSVPTKSGLPSGMPFTSQINSIVHWILWSATVRKCSLPLHIGSVNELAPFLTYGDDGLYTIPSHLTKSIDEIISTLKGYGLSPTAPDKGANVEIKRTSFTYLSGPVFLKRRIVLTPGGHRALLDLTSLARQPVWVNGPRRSVWNHEAQPIEIDAETRTIQLQNVLIELAWHQPQDFDHVLALVVKSAEASGLTIPRYSQEEARAIYDGRYYGIQHVSLPNNSDLIREGNMSDNKSTPEQQHESSRAMDAGATGAAAAAPAPPVAAAPASGLVGALVAEPQSGPSAEQWRTAYTLFGTVSWNANAGPGTILTVGRLGPGMNPYTQHIAAMYGGWAGGMDIRITIAGSGFIGGTLAVAAIPPGVDPESVNVLRMPHVLIDARGGVPLEVTLEDIRTSLYHPMGDTNTASLVIAVMTGLINPLGTDTLSVTVQLETRPGRDWVFFSLLPPTAGVASADPSQLLTRVALATSPEVRFGTGVLGILGLPSNPSVNRVYDVQSRTRGWSFPIPSSSVFMGDARNVEHNRRVMVQSSAPNNPLSDVFPDGFPDFVPQSDTEPDGGAVIAGQVLPHPGDNDNFWRLTPVVRGNTTAAINTIPERFNQVYFINLADEEAVSAATEELRFNGIQGIFGQRTNARAVQVMQGYVPRAEHIIRPAGFAGVGPQGPNVPIGFAGTMPNFNATASGADDLVPVWGPTLVHTASLLAGTTYELAENSMYVFSVSTSTSTFELGMLANGTWLGPAQLAGTGITWTEVLSVTYMGMRFAYNPLSGQGIGGESRRL
What is the function of this protein?
Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 35 nm in diameter, and consisting of 180 capsid proteins.  A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry.  The capsid encapsulate VP2 proteins and genomic or subgenomic RNA.  Attaches virion to target cells inducing endocytosis of the viral particle.  Acidification of the endosome induces conformational change of capsid protein thereby injecting virus genomic RNA into host cytoplasm (By similarity).
What are the official names of this protein?
Genome polyprotein.
What are the subcellular locations of this protein?
[Capsid protein]: Virion. Host cytoplasm.
Protein: DCUP1_ORYSJ
Sequence: MISATATAAFLAAAPASSSSCTTHRRRSGLPAISASLATASSTEEPLLVRAARGEDGLPRPPAWMMRQAGRYMAEYQALAKRHPSFRERSETTELIVEITLQPWRAFAPDGVILFSDILTPLPAIGVPFDISDSKGPVIQSPVRSEEQVRELTPIDFEKLRFVGESLKILRTEIDGQAALLGFVGAPWTIATYVVEGGMTNTYTNIKSMCHTAPNVLRGLLSHLADAISEYIIYQVNSGAQCIQIFDSWGGQLPPHVWEQWSKPYIKQIVNKIKIECPNVPLVLYINGNGGLLERMTDTGVDVIGLDWTVDMADGRRRLGNKISVQGNVDPAFLFSPLPVLTDEIHRVVKSAGPKGHILNLGHGVLVKTPEEAVAHFFDVTRSLRYDTLFQGCVTEVLEPVA
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase 1, chloroplastic, UPD1, URO-D1.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: IXTPA_CORGL
Sequence: MKLLLASNNAKKLKELQRILDQAGLDSVELLALRDVEAYDEPIEDGRTFADNAQIKARAGVTHTGIATIADDSGIAVEELNGMPGVLSARWSGAHGNDTANNELLLAQMEHVPDERRNAAFVSVCVLALPDGQEFVQEGRWEGQLLRGPKGENGFGYDPLFIPAEEIDGQGRSSAELSAEEKDALSHRGQALRGLVEKIAQVAAAS
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: BETB_YERPA
Sequence: MSRYGLQKLYINGAYTDSTSGDTFDAVNPANGECIAQLQAANAQDVDKAVAAAKQGQPVWAAMTAMERSRILRRAVDILRDRNDELAAIETADTGKPLSETRSVDIVTGADVLEYYAGLIPALEGQQIPLRGSAFVYTRREPLGVVAGIGAWNYPLQIALWKSAPALAAGNAMIFKPSEVTSLTALKLAGIYTEAGLPAGVFNVLTGSGDQVGQMLTEHPGIAKVSFTGGIASGKKVMANAAGSTLKDVTMELGGKSPLIIFADADLDKAADIAMMANFYSSGQVCTNGTRVFVPQALQAAFEQKIVERVKRIHIGDPSDERTNFGPLVSFQHRDSVMRYIDSGKREGATLLIGGYSLTEGALAHGAYVAPTVFTHCRDDMQIVREEIFGPVMSILSYQSEEEVIRRANDTEYGLAAGVVTQDLNRAHRVIHQLQAGICWINTWGESAPEMPVGGYKHSGVGRENGISTLEHYTQIKSIQVELGSFNSVF
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid.
What are the official names of this protein?
Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: LACE_RHIRD
Sequence: MDYSRLLKRSVSAALTAAALLCSTAAFAGEVTIWCWDPNFNVAIMKEAAERYTAKHPDTTFNIVDFAKADVEQKLQTGLASGMTDTLPDIVLIEDYGAQKYLQSFPGSFAALTDKIDFSGFAKYKVDLMTLEGQVYGVPFDSGVTGLYYRTDYLEQAGFKPEDMQNLTWDRFIEIGKEVKAKTGHEMMALDANDGGLIRIMMQSGGQWYFNEDGSLNITGNAALKAALETQARIVNERVAKPTSGSNDGIRALTSGDVASVLRGVWITGTVKSQPDQAGKWALTAIPKLNIEGATAASNLGGSSWYVLEASAEKDEAIDFLNEIYAKDLDFYQKILTERGAVGSLLAARTGEAYQKPDDFFGGQTVWQNFADWLVQVPAVNYGIFTNELDTAVTANFPALVKGTPVDEVLKAIEDQAAGQIQ
What is the function of this protein?
Part of the binding-protein-dependent transport system for lactose.
What are the official names of this protein?
Lactose-binding protein, LBP.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: NUDT6_RAT
Sequence: MWWASRARWLFSALLDVGGVGLRARRRTASSGLEITGSCGGELQGELDRFGGISVHLSRHRTLHRLDAAAFRRLLQAAIQQWRAEGRIAAWLHIPILQSHFIAPAASLGFCFHHAEPHLSTLTLWLGEGPSRLPGYATHQVGVAGAVFDVSTRKVLVVQDRNKLKNMWKFPGGLSEPGEDIGDTAVREVFEETGVKSEFRSLLSIRQQHRSPGAFGMSDMYLICRLQPRSFTINFCQQECLKCEWMDLESLARTKHTTPITSRVARLLLYGHREGFDKIDLSMEELPAVYTGLFYKLYHRGLPERYKAEMGTD
What is the function of this protein?
May contribute to the regulation of cell proliferation.
What are the official names of this protein?
Nucleoside diphosphate-linked moiety X motif 6, Nudix motif 6, Protein GFG.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family.
What are the subcellular locations of this protein?
Nucleus. Mitochondrion. Cytoplasm. Note=Subcellular location depends on the isoform.
Protein: RS18_ALCBS
Sequence: MARFYRRRKFCRFTAEGVEYIDYKDLDTLKAYITETGKIVPSRITGTKARYQRQLASAIKQARFLALLPYSDSHDN
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TRPF_GLOVI
Sequence: MRVKICGFTDPGQAQAAARLGVHALGFVCVPGTPRYVDAARLREIAAALPPFTFKVGVFVDAPVEAMRAAVEAGELQGVQLHGEESPETCAHLARTLPGILRIKALRVREPADLEKIALYVDAIEAVLLDAWHPTQAGGTGRTLDWKALQGFCPALPWMLSGGLRADNLAQALDILTPDAVDLSSGVENGVPGQKDLSKITQILHIAQGNTGQRRPPLCDGT
What are the official names of this protein?
N-(5'-phosphoribosyl)anthranilate isomerase, PRAI.
What is the protein family that this protein belongs to?
Belongs to the TrpF family.
Protein: CC018_MOUSE
Sequence: MNSRVPATQSWFSSHLPTTEPDLEPATAAEGSTTETATLSPETTSFNDTRIPDVAGGAAGVGTMLLSFGIITVIGLAVAMVLYIRKKKRLEKLRHQLMPMYNFDPTEEQDELEQELLEHGRDAASMQAAASLQVTQGKSTLPSQGPLQRPSRLVFTDVANAIHA
What are the official names of this protein?
Uncharacterized protein C3orf18 homolog.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ERS1_SCHPO
Sequence: MGKVSANNQSGFFKFYIDTALLLNAEFISSFTNCINSEYNGKVKISYSSSSQQFKVIVYEEHKREAFSLFEEIVQKLKRESTVYKKPRLDIHPFGQLHYDFTTLLNFQRYLDLGYGIEDVKIKENEDIVKSKVGKKPTSSDFYIPCLIKPKIITPFEWEGNFKQVIYSPTVYNGSFKRLFYLPDNNDLLKEFAHATNTKYKASLKDNKIVVLANNDQDINAMLEKMKHIENLVSQKVYEYPEETLVYAGKIAPCQLKFLKLKFENEILYTAMHTTSIFKSVFNILGSFYTMRLLRNKHDGDSYELVPVFAKNPSKTPPCNDNFKIFSDDIKLIGCKIFAGVSLNFSSPKPAHRFYELNKTSSNLSIPVLQKPSNFHSSSTELSDNSIHQGRRAVDPVVNQNNPSNFEEMIMNKLNKLPTIDKQILGTSSLTHFQDKTTAIEHSINKSNSKQPPRFKFQLPPRPTSNTLPLEPEEELVTRYSVSSDGNTVDEAITKQSQTFQLVNSNEFNEVNANDVHKSLRQNCAKLDFDDSKSKNLLSVECLELDKGSDCSTPKSGSLTPSIDMKFLRLQDEKMDDLGDNYYTILMSSNPVSSYGVGSLYLFQPKIVCSEKYINHEEIDNMNLKSLHRWLSRSLHVLQSFSGEIELNLEFGVILYPNISSDVSACSHGFMNIYKDLNLPRSYFADCITKSVSNIDSLLNTPVKILFGRTEYTYPLIEHEVLDSKNYFVFKGSLLFTDDKRNKTEDSTVFFSMICSSKLDQFAFYKDSKQSSTCTINFPLALWDSRLRIETKVPLNDAILTEFSKSIRFRNVNKDLLLVFGNMEDRVIIHSVTRINENSVPFNKNLLPHSLEFILKCSKVKSYDISPSSINSKEAFVCLDRSKESKPIESCFSLSIQSVYMQSQFKYNNSIRAGETAPWKLANKQFIGGAITENVSDLYTAAIIMVNQLGGIHPTI
What is the function of this protein?
Involved in RNAi-dependent heterochromatin formation and centromeric silencing.  Required for the conversion of centromeric pre-small interfering RNA transcripts into small interfering RNAs, histone H3 'Lys9' methylation, and the recruitment of the RITS complex to centromeric sequences.
What are the official names of this protein?
RNA-silencing factor ers1.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body.
Protein: RL35_UREPA
Sequence: MAKIRQKTKRAVAKRFSITKNGKLKRKHAYRSHLALGRSTKAKRHLRKDAIMSTSDTKRYTQCL
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: FPG_COLP3
Sequence: MPELPEVEVCRLGISPHVIAQEVSEVIIRNKRLRWPIPDEVCSAVGLPVLKVERRAKYLLLRFSTGTLLLHLGMSGTIRVIEQDTPVAKHDHFDLVFKHGKSLRLNDPRRFGAVLWLANDEDELGLLAKLGPEPLSDDFAEGYLFSKAKNRKVPIKTFLMNNHVVVGVGNIYANEALFQAGILPTAKAKDIDEHRMNSLTAIIKKVLSAAIAQGGTTLKDFTQADGRPGYFAQSLMVYGRAGEACVTCKTKLQEIRQSNRSSVFCPSCQQD
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: PPID_CANAL
Sequence: MTATPVYFDISCNGKPKGRVVFKLYDDVVPKTAANFRSLCTGDKGISPKSGKPLSYKDSIFHRVIKDFMCQGGDFTAPSDHLGTGGESIYGEKFEDENFKLNHNKPFLLSMANSGPNTNGSQFFITTVPTPHLDGKHVVFGEVIEGKSIVRQLERSEKGANDRPVEDWKIADCGELPANYEPVASGADDGTGDTYEEILTDNDTIDINNPQSVFAAVSKIKDIGTKLLKEGKLEKSYEKYTKANSYLNDYFPEGLSPEDLSTLHGLKLSCYLNAALVALKLKHGKDAIAAANNALEVEQIDDKSKTKALYRKGMGYILVKDEEQAQKILEEALELEPNDAAIQKGLQEAKHNIKLRRDKQKKAMAKFFS
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase D, PPIase D, Rotamase D.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ASTER_CANLF
Sequence: MSTNNMSDPRRPNKVLRYKPPPSECNPALDDPTPDYMNLLGMIFSMCGLMLKLKWCAWVAVYCSFISFANSRSSEDTKQMMSSFMLSISAVVMSYLQNPQPMTPPW
What is the function of this protein?
Component of the multi-pass translocon (MPT) complex that mediates insertion of multi-pass membrane proteins into the lipid bilayer of membranes (PubMed:36261528).  The MPT complex takes over after the SEC61 complex: following membrane insertion of the first few transmembrane segments of proteins by the SEC61 complex, the MPT complex occludes the lateral gate of the SEC61 complex to promote insertion of subsequent transmembrane regions (PubMed:36261528).  Within the MPT complex, the PAT subcomplex sequesters any highly polar regions in the transmembrane domains away from the non-polar membrane environment until they can be buried in the interior of the fully assembled protein (PubMed:36261528).  Within the PAT subcomplex, WDR83OS/Asterix binds to and redirects the substrate to a location behind the SEC61 complex (PubMed:36261528).
What are the official names of this protein?
PAT complex subunit Asterix, Protein WDR83OS homolog.
What is the protein family that this protein belongs to?
Belongs to the Asterix family.
Protein: RL32_TRIL1
Sequence: MAVPKKKTSKSRKNMRRAHDFLTAPSLSVCPQCKSPKMPHRACPSCGTYKGKEVAGAAKQA
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: AROC_MYCBO
Sequence: MLRWITAGESHGRALVAVVEGMVAGVHVTSADIADQLARRRLGYGRGARMTFERDAVTVLSGIRHGSTLGGPIAIEIGNTEWPKWETVMAADPVDPAELADVARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTVARAFLRQALGVEVLSHVISIGASAPYEGPPPRAEDLPAIDASPVRAYDKAAEADMIAQIEAAKKDGDTLGGVVEAVALGLPVGLGSFTSGDHRLDSQLAAAVMGIQAIKGVEIGDGFQTARRRGSRAHDEMYPGPDGVVRSTNRAGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGDEAVAIHQRSDVCAVPAAGVVVETMVALVLARAALEKFGGDSLAETQRNIAAYQRSVADREAPAARVSG
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: O19_CONST
Sequence: MKLTCMMIAAVLFLTTWTFVTADDSRYGLKNLFPKARHEMKNPEASKLNKREGCSSGGTFCGIHPGLCCSEFCFLWCITFID
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav).
What are the official names of this protein?
Omega-conotoxin-like 9.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RPOC_PSE14
Sequence: MKDLLNLLKNQGQVEEFDAIRIGLASPEMIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVALAKVRRERMAHIELASPVAHIWFLKSLPSRIGLLMDMTLRDIERVLYFESYVVIDPGMTTLEKGQLLNDEQYFEALEEFGDDFDARMGAEAVRELLHAIDLEHEIGRLREEIPQTNSETKIKKLSKRLKLMEAFQGSGNLPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLSAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIFGKLEMRGLATTIKAAKKMVERELPEVWDVLAEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTREAINAKGEGRVFADLQEVDRVFRAGEAALHAKVKVRIHETVNDRDGGSVKNTRIVDTTVGRALLFQVVPAGLSYDVVNQPMKKKAISKLINQCYRVVGLKETVIFADQLMYTGFAYSTISGVSIGVNDFVIPDEKARIIDAATEEVKEIESQYASGLVTQGEKYNKVIDLWSKANDEVSKAMMSNLSKEKVIDRHGVEVDQESFNSMYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLSVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEVDCGTEHGLLMTPHIEGGDVVEPLGERVLGRVIARDVFKPGTEDVIVPAGTLVDEKWVEFIELNSIDEVIVRSPISCETRYGICAKCYGRDLARGHQVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRTSAADSVQVKNGGTVRLHNLKHVERVDGHLVAVSRSGELAIADDFGRERERYKLPYGAVISVKEGDKVDAGSIVAKWDPHTHPIVTEMKGTVTYVGMEEGITIKRQTDELTGMTNIEVLDAKDRPAAGKDIRPAVKMVGLDGKDLLLPGTDVPAQYFLPANALVGVADGAQIAIGDVIARIPQETSKTRDITGGLPRVADLFEARRPKEASILAEVSGTIAFGKETKGKRRLVITPNDGSDPYEELIPKWRHLNVFEGEQVNRGEVISDGPSDPHDILRLLGVSALAKYIVNEIQDVYRLQGVKINDKHIETILRQMLRKVEIAESGDSSFIKGDQMELTHVLVENERLSTEDKFVSKFTRVLLGITKASLSTESFISAASFQETTRVLTEAAVTGKRDYLRGLKENVVVGRLIPAGTGLAYHSERKRRREMDKPTRVSASEVEAALTEALNSSGN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.