PharMolix/UniProtQA huggingface dataset:
Protein: SCBT_MESMA
Sequence: MKAALLLVIFSLMLIGVLTKKSGYPTDHEGCKNWCVLNHSCGILCEGYGGSGYCYFWKLACWCDDIHNWVPTWSRATNKCRAK
What is the function of this protein?
This toxin increases the peak sodium current, slows down the inactivation of sodium channels (Nav), and prolongs the action potential of dorsal root ganglion neurons, which indicates that it behaves as a classical alpha-toxin.  It binds to mammal brain and insect sodium channels, but with a different manner.  This peptide may bind to a distinct receptor site on mammal brain sodium channels, which is unconnected with that for BmKAS (a beta-toxin), BmKIT2 (a beta-toxin) or BmK I (an alpha toxin).  In contrast, the receptor site for BmKabT on insect sodium channels might be closely related to that for the beta-insect depressant toxin BmKIT2.  Possesses potent toxicity in mice but induces only paralysis in cotton bollworm.
What are the official names of this protein?
Toxin BmKBT, BmK BT, BmKabT, BmK abT.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: LUXE_PHOLE
Sequence: MSTLLNIDATEIKVSTEIDDIIFTSSPLTLLFEDQEKIQKELILESFHYHYNHNKDYKYYCNIQGVDENIQSIDDIPVFPTSMFKYSRLHTADESNIENWFTSSGTKGVKSHIARDRQSIERLLGSVNYGMKYLGEFHEHQLELVNMGPDRFSASNVWFKYVMSLVQLLYPTTFTVENDEIDFEQTILALKAIQRKGKGICLIGPPYFIYLLCHYMKEHNIEFNAGAHMFIITGGGWKTKQKEALNRQDFNQLLMETFSLFHESQIRDIFNQVELNTCFFEDSLQRKHVPPWVYARALDPVTLTPVEDGQEGLMSYMDASSTSYPTFIVTDDIGIVRHLKEPDPFQGTTVEIVRRLNTREQKGCSLSMATSLK
What is the function of this protein?
Acyl-protein synthetase activates tetradecanoic acid.  It is a component of the fatty acid reductase complex responsible for converting tetradecanoic acid to the aldehyde which serves as substrate in the luciferase-catalyzed reaction.
What are the official names of this protein?
Long-chain-fatty-acid--luciferin-component ligase, Acyl-protein synthetase.
What is the protein family that this protein belongs to?
Belongs to the LuxE family.
Protein: DF230_ARATH
Sequence: MRSVIWFIVSYTLMLLVLRGGKEVEAEKLCTTIGDLDGKCSQDGEKLCMRYMTDQSKKKFLSCTCNNVVMLHKYKHYCECQSHCTPKQT
What are the official names of this protein?
Putative defensin-like protein 230, Putative S locus cysteine-rich-like protein 24, Protein SCRL24, SCR-like protein 24.
What is the protein family that this protein belongs to?
Belongs to the DEFL family.
What are the subcellular locations of this protein?
Secreted.
Protein: NDC80_YARLI
Sequence: MNASAHKKRLSMMPGTSSASRPSMAGLPQRNNPPPQREPATPAVSELMRSSRRSMAFGRNPRQSSFGLVPQTPMAPMHTRDPRPVRDRHYQQQISQQIYEYLVTNHFEQETRHPLNQRTLSNPTQKDFKTMFEWIFRRIDPGYPFHKSIENEVHAVLRAAKYPWLDSITKSQIVAVGGQSWAYFSGMLHWMVELNTTIEKYHNHDYSGDDGPSLVDEIFNRHARESYFAYLQGDDRFARPDAELCLAEENAEFQEILAEQRAQNPLPEGEDDELDEELSRLEAKWGKIEEAKLLGKNLADDIVKLGAFVDARKEHNARYASQMSQATAEEDNVTSEVESLSRQKLKLQQTIQDQGLSPAELDKLHLDMERQQKALNSLDEIIDEGRQVVSNKESTALAVFDALDRVIKEYTSSVLSYNAWVASDNDLPEIPESVYLIDLREPLSEENLGRHPSVILGGVDPRNQIRPEIVRICNMVTSKVKALQEEALRLQEEIETNQEKLVSQKRHIGELEAKSRRLRETRNALEDSASMNENENSQNTERLENQFVQAQSETALAQSQLKGLQVRLQDAEHERNKLSVEVQQARERLSQDILKQAEVMVAFKAMVQTKLQDFEMFVRANVEEEIRGDHN
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein NDC80.
What is the protein family that this protein belongs to?
Belongs to the NDC80/HEC1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: DRTS_TRYBB
Sequence: MLSLTRILRKKIPVHELAGKISRPPLRPFSVVVASDEKGGIGDGGTIPWEIPEDMQYFRRVTTNLRGKNVKPSPSKRNAVVMGRKTWDSLPPKFRPLSNRLNVVLSRSATKEQLLAGIPDPIKRAEAANDVVAVNGGLEDALRMLVSKEHTSSIETVFCIGGGTIYKQALCAPCVNVLQAIHRTVVRPASNSCSVFFDIPAAGTKTPEGLELVRESITDERVSTGAGGKKYQFEKLVPRNSEEEQYLNLVGRIIDEGCTKCDRTGVGTRSLFGAQMRFSLRNNRLPLLTTKRVFWRGVCEELLWFLRGETNAKLLSDKGIHIWDGNGSRAFLDSRGLTDYDEMDLGPVYGFQWRHFGADYISCKVDSEGKGVDQIANIVKSLIENPDDRRMICTAWNPAALPRMALPPCHMMAQFYVSNGELSCMLYQRSCDMGLGVPFNIASYALLTFLMAKASGLRPGELVHTLGDAHVYSNHVEPCRKQLKRVPRPFPFIVFKQDKEFLEDFQESDIEVIDYSPYPVISMEMAV
What is the function of this protein?
Bifunctional enzyme.  Involved in de novo dTMP biosynthesis.  Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP (By similarity).
What are the official names of this protein?
Bifunctional dihydrofolate reductase-thymidylate synthase, DHFR-TS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidylate synthase family.
Protein: PURNU_MYCTO
Sequence: MLASTRHIARGDTGNVSVRIRRVTTTRAGGVSAPPFDTFNLGDHVGDDPAAVAANRARLAAAIGLPGNRVVWMNQVHGDRVELVDQPRNTALDDTDGLVTATPRLALAVVTADCVPVLMADARAGIAAAVHAGRAGAQRGVVVRALEVMLSLGAQVRDISALLGPAVSGRNYEVPAAMADEVEAALPGSRTTTAAGTPGVDLRAGIACQLRDLGVESIDVDPRCTVADPTLFSHRRDAPTGRFASLVWME
What is the function of this protein?
Purine nucleoside enzyme that catalyzes the phosphorolysis of adenosine and inosine nucleosides, yielding D-ribose 1-phosphate and the respective free bases, adenine and hypoxanthine.  Also catalyzes the phosphorolysis of S-methyl-5'-thioadenosine into adenine and S-methyl-5-thio-alpha-D-ribose 1-phosphate.  Also has adenosine deaminase activity.
What are the official names of this protein?
Purine nucleoside phosphorylase MT2208, Adenosine deaminase MT2208, S-methyl-5'-thioadenosine phosphorylase MT2208.
What is the protein family that this protein belongs to?
Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.
Protein: DNLJ_NITSB
Sequence: MIKNYQEYKEAVEKLKRWAYAYYVLDNPEVPDEVYDKLYREVEEYEKAHPDQIDPTSPTQRIGAEPAKEFKKIKHLSKMWSMEDVFNQREMHEWLERVYKNAGRKDLQFYIEPKFDGASLNLIYENGLLKSAATRGDGEVGEDVTANAKTIPSIPLGIDYKGLIEIRGEVVIRKDDFEKLNHERALKGESTFANPRNAAAGSLRQLDPKVTAQRKLYFYPWDIGYNTLNFKYQHEKMDFVYQQGFIKPFKRAICENEEEIQQLYEEFSKERDKLPVMLDGMVVKVDEIALHEILGYTVKYPRWMVAYKFPAVEKMTRIIDIVPQVGRTGVITPVAILEPVEIEGVVVERATLHNYAEIERKDIRIGDMVIVIRSGDVIPEVTKVLTQYRTGKEKKVERPKVCPVCGQPVLDEGILIKCQNLSCPARVVNSIIYFASKQCLDISGLGEATVKLLYEKGLVKDVVDLFKLKKEDLLRLPGFAEKKAQNLIDATQSVKGVECWRFVNALGIEHIGEVASKKLCEKFGLDWYKAPKEKLYEIEGFGPEMVRSIEEFVEVNKEKIEKLIELLQPTEPKKEEEVENSPLAHKTVVLTGEMKLPRSKIKELLERAGAHVTNSVSHHTDYVFYGENPGSKFQKAQQLGVPLLPEEKMWELLKEAGIEA
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: MOCO2_AEDAE
Sequence: MEFEQEYTAEEALNIEKEFTRLKGKHYMDHAGTTLYAESQIRAVHDMLAQNLFCNPHSSPLTGKLLQQVRHRLLRFFNTSPSDYSLVFTSGATASLKLVAESFRFRPPDEPESSPDEGAFVYLRDNHTSVLGMRSVVGTERIDPLEPEELLRHLKVSARCSGGTKPSLLVFPAQNNFNAAKYPLDLVEEIQQNGLSGYDDERFYVCLDAASYVSTNFLDLGRYRPDFVCMSFYKIFGYPTGLGALLIRNGSEDVLDKKYYGGGTIKIMLSGQNLHLKHDDLVTRFEDGTQPFLSIISLLEGMNTIQRLIPAANGYRPMERISKHVFSLAKYCYRKLGTLQHANGKKAILFYSDTRYETRDRQGGIVTFNVLKDDGSHLGFSEFAKFAGQHQIYVRTGCFCNAGSCQKHLGLTDEDILMFYEMGKVCGDDTDMIEGRPTGTVRVSFGYMNKKEDVNRLVDMINDCFVSKAVSNVAMVSPIRNVIKNEGIALKAIYLYPIRSCGGYRITAAWPLTERGLKYDREFTIVDSNGNPLMRNKHAEMSTIHPKIDPSLNFLILTHPFMEDLILKIRKLPTEFNDGESIDLGDAAAAWISKALRMPKLRLLRTSATDRKPPHKLLMINWDAMKTLSDDEGVESDATMSWLVDHFRGSLIVEGKAEEDLQGWKEVKIGKKRFKVQANCSRCPMIHVDQSGEAIPADSLKAIANVFTKKIPLGVHLTAVDEGFPEGVLECGSILEPVRQSDSPKAHIIKDSVSTRYNFLVK
What is the function of this protein?
Sulfurates the molybdenum cofactor.  Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
What are the official names of this protein?
Molybdenum cofactor sulfurase 2, MCS 2, MOS 2, MoCo sulfurase 2, Molybdenum cofactor sulfurtransferase 2, Protein maroon-like 2, Ma-l 2.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
Protein: GRCA_VIBCH
Sequence: MIQGIQITKAANDDLLNSIWLLDSEKNEARCVAALKGFEADQVVSINDLGQFESREVAIEAAPRIEGGQHLNVNVLKRETLEDAVAHPEKYPQLTIRVSGYAVRFNSLTAEQQRDVIARTFTESL
What is the function of this protein?
Acts as a radical domain for damaged PFL and possibly other radical proteins.
What are the official names of this protein?
Autonomous glycyl radical cofactor.
Protein: RIR2_IIV3
Sequence: MEYEHLWLTAYGCLAVVGAVVVYCAIKQSLVTNWWFYGSIYPQVKLMADRTTFKPFEYPGCYDKWDTHEHAHWSFKELNMQDDVHDWHNRLSEAEKTFLVQILRFFTQGDVDVAVGYVQYLQLFQQPEVRMMLFSFGAREAMHIASYSHLISTLNLPDVTYQEFLKYKAMKDKHEFVFNSRFKSTTVGRFFNYLLFGYDTHLEEIAVKIALFSAFIEGVQLFSSFIMLLNFTRHGLMKKMGQIIQWSIADETHHTNSMMELFSTLVVENKSHIRLGVLEARVRDTARKIVQLEDGFIDLAFSMGEMRQLTADDVKSYIRYITNRRLQTMGYLPLYSVVENPLPWVEDLLNAPSHTNFFENKPTEYAKASLTGDWPW
What is the function of this protein?
Ribonucleoside-diphosphate reductase holoenzyme provides the precursors necessary for viral DNA synthesis.  Allows virus growth in non-dividing cells.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity).
What are the official names of this protein?
Probable ribonucleoside-diphosphate reductase small subunit 048L, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
Protein: NINL_HUMAN
Sequence: MDEEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPELCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQSLDFSVDEKVNLLELTWALDNELMTVDSAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLEPQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWSPDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHYQDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLALRHHSHLQQIRREAEAELSGELSGLGALPARRDLTLELEEPPQGPLPRGSQRSEQLELERALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQALPKDGLVAGSGQEGTRGLLPLRPGCGERPLAWLAPGDGRESEEAAGAGPRRRQAQDTEATQSPAPAPAPASHGPSERWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQEASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVRLVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV
What is the function of this protein?
Involved in the microtubule organization in interphase cells.  Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly.  May play a role in ovarian carcinogenesis.
What are the official names of this protein?
Ninein-like protein.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Note=In interphase cells, NINL is transported to the centrosomes by the dynein-dynactin motor complex (PubMed:16254247). During centrosome maturation, PLK1 directly phosphorylates NINL resulting in its release into the cytoplasm (PubMed:16254247).
Protein: EF1A_IGNH4
Sequence: MSKKEKPHMNLIVIGHVDHGKSTLVGHLLYELGFVDEKTLKMLEEEAKKRGKESFKYAWLLDKLKEERERGVTIDLTFMKFETPKYYFTIIDAPGHRDFIKNMITGASQADAAILVVSARPGEFEAGMSAEGQTREHILLAKTMGIDQIIVAVNKMDATEPPWSEKRYKQIVETLKKFMKGLGFKVDEIPFVPVSAWTGDNIIKRSENMPWYKGPTLVEALDNLKPPSVEKWAKLPLRIPIQDVYSITGVGTVPVGRVETGVLKVGDKVVFMPPGVGGEVRSIEMHHEKIEQAMPGDNIGFNVRGVSKNDIKRGDVAGHPENPPTVADQFTARVFVIWHPSAIAVGYTPVIHAHTASVASRIIEIKQKIDPRTGKVIEENPSFLKPGDAAVVVFKPLKPMVIEKFQEFQPLGRFAMRDMGKTVGIGIVTDVKPAKVEIKMKK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha, EF-1-alpha, Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VHUU_METMP
Sequence: MVDEAKLNLIEIVLRAYDPUYSCAAHMIVKDEQGKVLLEVKKEE
What are the official names of this protein?
F420-non-reducing hydrogenase vhu subunit U.
What is the protein family that this protein belongs to?
Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
Protein: NTPP_MYCSJ
Sequence: MTTRVVLGSASSGRLKVLRQAGIEPLVVVSGVDEDAIVAALGAAAPPDQVVCALAAAKAASVVESLPTEVATDCVVIGCDSMLQLDGRLTGKPGTPAAARAQWQQMAGRSGELYTGHCLVRVRDGVAGRREVEAAATTVRFGTPPPADLAAYVDSGEPLGVAGAFTLDGLGGWFLDGVDGDPSNVIGLSLPLVRRMLDRLDLSVPALWTR
What is the function of this protein?
Nucleoside triphosphate pyrophosphatase.  May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
What are the official names of this protein?
Nucleoside triphosphate pyrophosphatase, Nucleotide pyrophosphatase, Nucleotide PPase.
What is the protein family that this protein belongs to?
Belongs to the Maf family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAGP_ECOLI
Sequence: MPAPVVLILAAGRGECFLASGGNTHKCIGWRQSPEVAPYRWPFEENGRTFDLAIEPQITTNDLRLMLRLALAGGGITIATQETFRPYIESGKLVSLLDDFLPQFPGFYLYFPQRRNIAPKLRALIDYVKEWRQQLA
What are the official names of this protein?
Putative LysR family substrate binding domain-containing protein YagP.
What is the protein family that this protein belongs to?
Belongs to the LysR transcriptional regulatory family.
Protein: SRKA_ECOLI
Sequence: MNNSAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYENRVYQFQDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFYFAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLFEDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDLDDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVYYLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY
What is the function of this protein?
A protein kinase that (auto)phosphorylates on Ser and Thr residues (PubMed:17302814).  Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species.  Protects cells from stress by antagonizing the MazE-MazF TA module, probably indirectly as it has not been seen to phosphorylate MazE, MazF or MazG (PubMed:23416055).  Probably involved in the extracytoplasmic stress response (PubMed:9159398).
What are the official names of this protein?
Stress response kinase A, Serine/threonine protein kinase YihE, Serine/threonine-protein kinase SrkA.
What is the protein family that this protein belongs to?
Belongs to the SrkA/RdoA protein kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN665_PONAB
Sequence: MGEAFYTVKLERLESHDTEGLSFQEVQKNTYDFECPWKDDEGNSKRVLTLQKENLPGRRDQRDRRAAGNRLIENQLGVSFQSHLPELQQFQGEGKIYEYNQVEKSLSNRGKHYKCDECGKVFNQNSRLTSHKRIHTGEKPYRCNECGKAFTVRSNLTIHQVIHTGEKPYKCNECGKVFSQPSNLAGHQRIHTGEKPYKCNECGKAFRAHSKLTTHQVIHTGEKPYKCNECGKCFTQNSHLASHRRIHTGEKPYKCNECGKAFSVRSSLTTHQTIHTGEKPYKCNECGKVFRHNSYLTKHRRVHTGEKPYKCNECGKAFSMHSNLTKHQIIHTGEKPFKCNECVKVFTQYSHLANHRRIHTGEKPYRCDECGKAFSVRSSLTTHQAIHTGEKPYKCNDCGKVFTQNSHLASHRGIHSGEKPYKCDECGKAFSQTSQLARHWRVHTGEKPYKCNECGKAFSVHSSLTTHQTIHTGQKPYKCNDCGKVFRHNSYLAVHQRIHTGEKPYKCNECGKAFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEKPYRCNECGKAFSVRSTLTTHMAIHTGDKPYKCNECGKVFTQNSNLAKHRRIHSG
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 665.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: APAH_AGGAC
Sequence: MATYLIGDLHGCYDEFQMLLERVRFDPAQDTLYLTGDLLARGDNSLACLRLVKSLGNAARTVLANHDLHFISTALGVKKIKPRDRVDAIFAAEDFFELVNWLRCQPLLIHNPAQNFVLVHAGISPDWDLTAAKVCANEVENVLRHGNYRYLVENMYAEQPDRWSPHLQGLDRLRYSINVLTRMRFCYLDHRLDFACKLSIKDAPKALAPWFALDNPLYQTGNIVFGHWASLVDETTPPNIYGLDTGCVWGNRLTMLRWEDKQYFTQSAVKKSNAF
What is the function of this protein?
Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.
What are the official names of this protein?
Bis(5'-nucleosyl)-tetraphosphatase, symmetrical, Ap4A hydrolase, Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase, Diadenosine tetraphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Ap4A hydrolase family.
Protein: VATC_ASCSS
Sequence: MSEFWVISAPGDKTPQQTYERLQKATMGSGQNLSNCYKFSIPELKVGTLDSLIGLTDDLGKLDTFCEGVCRKVASYMGEVLEDQKDKLSSNLSAGEGTLVNFMHRFQWNMAKYPTKQPIKSLTEILSKVVTQVDTDLRSKSQAYNNLKSSLQNMERKATGSLLLRNLSQIVKKDDFIDGSEYLRTVIVAVPVALFGEWEKNYESLADYVAPKSSRLLTQDEEYGLFATSIFKKVYEEFKYNCSRYKFFVREFNFNEQDSVVRQDQINKIASEKRKMLGPLLRWLKVNFSEVFTAWIHIKALRVFVESVLRYGLPVNFQAVVLDPPKKNRKRLRDVLNNLYCKLDSTGLTNVDAEDSVPGLSLGMQEYYPYVFYKVILDFESRSF
What is the function of this protein?
Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).  Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity).
What are the official names of this protein?
V-type proton ATPase subunit C 2, V-ATPase subunit C 2, Vacuolar proton pump subunit C 2.
What is the protein family that this protein belongs to?
Belongs to the V-ATPase C subunit family.
Protein: PGK_MYCGA
Sequence: MINYNKKTLKDVDLKDKTVIVRVDFNVPIKDNKVIDDTRIVQALDTIKYLIEQNCKIVLLSHLSRIKSLEDISSKKKSLRPVYENLKTKLNNVKFLEENVGYDVVEAVKQLKHQEVLLLENTRYNDVDNQGEVVKKESKNSPELGRFWASLADVFVNDAFGTSHRAHASNVGIAANISQSCIGFLVQKELEALSKLTNNPQRPFVVILGGAKVSDKLKVIESLLKSADQILIGGGMVNTFNKAKGYHIGKSLFEPEMLETAKKILAEDKDNKIILATDQMVTKASTITDIKTAPAGKCVFAKDEAENEDFEALDIGDESIKTFKSYIAKAKSIFWNGPLGVFENPNYERGSYEIAKAISESDSYSVIGGGDSAAAANQFKLADKFSFVSTGGGASLTFMEQTVLPGIEAIQSK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARPU_BPO12
Sequence: MLLPEIDEKATVKRCKRKLREYPRWREIAHDSAEQKITQEFTFMPRGGSGVNKPVENIAVRRVDALSELEAIEQAVNGLYRPDYRRILIEKYLAYPPQPNWKIAQAIGFERTAFQELLKHSILAFAELYRNGQLVVER
What is the function of this protein?
May be involved in the regulation of muramidase export.
What are the official names of this protein?
Putative autolysin regulatory protein ArpU.
Protein: HUTG_RHOOB
Sequence: MMENLLIPPPPWTGRMDGTSSHHLRWHQAVTPLQDGVEPGACVFIGFSSDEGVERNKGRRGASRGPDALRSALSSMALAEPLRAYDAGTVAVTDNRLEAGQEALGAVVAATLDAGQFPVVLGGGHEVAFGTYLGLAQASVRTPGKRIGILNLDAHFDLRSDPVPSSGTPFRQILEREHAAGTTLQYSVLGISQPSNTTALFDTARGYDVRYLLDDECSVSDRHRVAVFVSEFLSDVDLVYLTIDLDVLPAAVAPGVSAPAAYGVPAETIQFVCDAIAASGKLAVVDVAELNPSFDIDNRTARTAARFIHRIVTKRIPIVR
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: CALRL_PAROL
Sequence: MVVLILLCDITKFFVEGSLGSNETEHQHPTNVYHDVGVTRDKIVTAQFECYQKIMKDSTHSRQEPLCNRTWDGWLCWDDTKAGVISEQHCPDYFQDFDPSEMVTKICADTGDWFLHPVSNRTWSNYTRCNQHTNEVRVTAMNLFYLALIGHGLSLTSLLISLGIFFHFKSLSCQRITLHKNLFFSFVLNSVITIVLLTAVANNQEVVQSNPTSCKVSQFIHLYLFGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYLLGWGFPLIPATIHAVARSYYYNDNCWISSKTSLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESSLYMKAVRATLILVPLLGIQYVLLPYKPEGRVSSEIYDYIMHILMHYQGLLVATIFCFFNGEVQAVLRRHWNQYNIQFGSSIGNHSDALRSASYTASSITEVQGCYSIDGHTEHMNGKGCHEADASILKSDNPFA
What is the function of this protein?
Receptor for calcitonin-gene-related peptide (CGRP) (By similarity).  Receptor specificity may be modulated by accessory proteins.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity).
What are the official names of this protein?
Calcitonin gene-related peptide type 1 receptor, CGRP type 1 receptor, Calcitonin receptor-like receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PCHE_PSEAE
Sequence: MDLPPDSRTALRDWLTEQLADLLGEPLADVRALADDDDLLGCGLDSIRLMYLQERLRARGSTLDFAQLAQRPCLGAWLDLLACADRLSAPATVALPTAQDRDQPFELSSVQQAYWLGRGAGEVLGNVSCHAFLEFRTRDVDPQRLAAAAECVRQRHPMLRARFLDGRQQILPTPPLSCFDLQDWRTLQVDEAERDWQALRDWRAHECLAVERGQVFLLGLVRMPGGEDRLWLSLDLLAADVESLRLLLAELGVAYLAPERLAEPPALHFADYLAHRAAQRAEAAARARDYWLERLPRLPDAPALPLACAPESIRQPRTRRLAFQLSAGESRRLERLAAQHGVTLSSVFGCAFALVLARWSESAEFLLNVPLFDRHADDPRIGEVIADFTTLLLLECRMQAGVSFAEAVKSFQRNLHGAIDHAAFPALEVLREARRQGQPRSAPVVFASNLGEEGFVPAAFRDAFGDLHDMLSQTPQVWLDHQLYRVGDGILLAWDSVVGLFPEGLPETMFEAYVGLLQRLCDSAWGQPADLPLPWAQQARRALLNGQPACATARTLHRDFFLRAAEAPDADALLYRDQRVTRGELAERALRIAGGLREAGVRPGDAVEVSLPRGPQQVAAVFGVLAAGACYVPLDIDQPPARRRLIEEAAGVCLAITEEDDPQALPPRLDVQRLLRGPALAAPVPLAPQASAYVIYTSGSTGVPKGVEVSHAAAINTIDALLDLLRVNASDRLLAVSALDFDLSVFDLFGGLGAGASLVLPAQEQARDAAAWAEAIQRHAVSLWNSAPALLEMALSLPASQADYRSLRAVLLSGDWVALDLPGRLRPRCAEGCRLHVLGGATEAGIWSNLQSVDTVPPHWRSIPYGRPLPGQAYRVVDTHGRDVPDLVVGELWIGGASLARGYRNDPELSARRFVHDAQGRWYRTGDRGRYWGDGTLEFLGRVDQQVKVRGQRIELGEVEAALCAQAGVESACAAVLGGGVASLGAVLVPRLAPRAEGSMDLPAAQPFAGLAEAEAVLTREILGALLEAPLELDDGLRRRWLDWLADSAASALPSLDEALRRLGWQAAGLTAMGNALRGLLAGEQAPAALLLDPWLAPQAVAARLPDGREALARLLEALPTPAAGERLRVAVLDTRAGLWLDQGMASLLRPGLELTLFERSRVLLDAAATRLPERIVVQALDDGLLPAEHLGRYDRVISFAALHAYEASREGLALAAALLRPQGRLLLVDLLCESPLALLGAALLDDRPLRLAELPSLLADLAAAGLAPRCLWRSERIALVEALAPGLGLDAAALQAGLEQRLPQAMRPERLWCLPSLPLNGNGKVDRRRLAESMTRALGECRHEPSAEEPLEAHEQALAECWEAVLKRPVRRREASFFSLGGDSLLATRLLAGIRERFGVRLGMADFYRQPTLAGLARHLQVQTVEIEETQLEEGVL
What is the function of this protein?
Involved in the biosynthesis of the siderophore pyochelin (PubMed:9846750, PubMed:11208777).  Accepts salicylate activated by PchD at the first peptidyl carrier domain (ArCP), and activates and fixes one molecule of cysteine at the second peptidyl carrier domain (PCP1) via a thioester linkage to the phosphopanthetheine moiety (By similarity).  Then catalyzes the condensation reaction between the salicylate bound to the first site and the cysteine bound to the second site, and the cyclization of the cysteine to form the salicyl-thiazolinyl-S-PCP1 intermediate at the second site (By similarity).  When this intermediate is released by the action of a thioesterase, it produces the antifungal antibiotic dihydroaeruginoic acid (Dha or hydroxyphenyl-thiazolinyl-carboxylate) (PubMed:11208777).
What are the official names of this protein?
Pyochelin synthase PchE, L-cysteine--[L-cysteinyl-carrier protein] ligase, Nonribosomal peptide synthase PchE.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.