PharMolix/UniProtQA huggingface dataset:
Protein: RF2_HELP2
Sequence: MDNYTYSELLKSLQNKCDNIALIIKPEKIKQELERIEKEQEDPNFWQDVLKARDTNKEKVRLNRLLETYQKTKDSLDESVELFELAQNDNDEVTLSLLYEEAPTLEHSVQKVEIEIMLSGENDASNAIITIQPGAGGTESQDWASILYRMYLRWAERRGFKSEILDYQDGEEAGIKGVAFIIKGENAYGYLKNENGVHRLVRISPFDANAKRHTSFASVQISPELDDDIDIEIDEKDVRYDYYRASGAGGQHVNKTESAVRITHFPTGIVVQCQNDRSQHKNKASALKMLKSKLYELELEKQQNSTKNEEKSEIGWGHQIRSYVLAPYQQVKDARSNIAYSNVEAILDGDIDAILEGVLIAKA
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC2_RHORU
Sequence: EGDAAAGEKVSKKCLACHTFDQGGANKVGPNLFGVFENTAAHKDNYAYSESYTEMKAKGLTWTEANLAAYVKNPKAFVLEKSGDPKAKSKMTFKLTKDDEIENVIAYLKTLK
What is the function of this protein?
Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway.  However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
What are the official names of this protein?
Cytochrome c2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
Protein: ORN_DICNV
Sequence: MDKKNNLVWIDLEMTGLDPQHDEIIEIATIVTDAQLNILAEGPVIAVYQPEPILAQMDAWNQKHHGASGLIERVRQSSFNTLEAEAQTLSFLEQYSEKGRSPICGNSICQDRRFLSRLMPRLEAFFHYRNLDVSTIKELVARWYPEHYFHKNTTHQALQDIRDSIDELRHYRQRIFVNPS
What is the function of this protein?
3'-to-5' exoribonuclease specific for small oligoribonucleotides.
What are the official names of this protein?
Oligoribonuclease.
What is the protein family that this protein belongs to?
Belongs to the oligoribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRSA2_STRPQ
Sequence: MKQMNKLITGVVTLATVVTLSACQSSHNNTKLVSMKGDTITVSDFYNETKNTELAQKAMLSLVISRVFETQYANKVSDKEVEKAYKQTADQYGTSFKTVLAQSGLTPETYKKQIRLTKLVEYAVKEQAKNETISKKDYRQAYDAYTPTMTAEIMQFEKEEDAKAALEAVKAEGADFAAIAKEKTIAADKKTTYTFDSGETTLPAEVVRAASGLKEGNRSEIITALDPATSKRTYHIIKVTKKATKKADWKAYQKRLKDIIVTGKLKDPDFQNKVIAKALDKANVKIKDKAFANILAQFAKPNQKQPAQK
What is the function of this protein?
Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins.
What are the official names of this protein?
Foldase protein PrsA 2.
What is the protein family that this protein belongs to?
Belongs to the PrsA family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RS12_DICNV
Sequence: MATINQLVRKPRVKLVDKNNVPALQECPQKRGVCTRVYTTTPKKPNSAMRKVARTRLTNKYEVTAYIGGEGHNLQEHSLVLIRGGRVKDLPGVRYHIVRGALDTAGVKDRKKGRSKYGAKRPKA
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: MASY_DICDI
Sequence: MLRGIEIRGKVDKNVKSILTEECLTFLGELERRFGGIRKNLLQKRLDRQIDINNGILPSFLKDSDCKRATDKNWKCSSVPLEIQDRRVEITGPTDRKMVINALNSGAKVFMADFEDANCPNWENSIHGQQNMIDANNRTISFTSAEGRKYELNKQVAVLFVRPRGWHLNEDHLAIDGLSMSGSLFDFGCYIFHNHQILKNRNSNPYFYLPKMESHLEARLWNDVFVFSQNYLGMPIGTIKATVLIETILASFEMDEILYELRDHSAGLNCGRWDYIFSFIKKFQSYPDKMLPDRAKVTMTSPFMDSYVKLLIYTCHKRGVHAMGGMAAQIPIKNNEQANNAAMEKVRLDKQREVRAGHDGTWVAHPALIPIAMEQFNTHMKSQNQISYIPSSTAPNFEEIAKSLLSVDPVKPGDITEDGFRSNIVVGILYLEAWLNGNGCVPIHNLMEDAATAEISRSQIWQWIKHKAPLPDGKSFVTLQYYNRIFKEESDKLEKAHPNSKTLTDAIQIFNNLIVSPNFIDFLTPSCYKFVVDSERKTFSPKL
What are the official names of this protein?
Malate synthase.
What is the protein family that this protein belongs to?
Belongs to the malate synthase family.
Protein: APT_ECOLU
Sequence: MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFDLGGEQRLEKQGITSYSLVPFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YORC_TTV1K
Sequence: MLPLMAAISSSSLGIGTSSYSPRYTILSSLIVYTLMRKTRAPFLLSSSFFQSFSLYYKSSLLNSMLMLPLLLHIPYYVKHNKL
What are the official names of this protein?
Uncharacterized 9.4 kDa protein.
Protein: YCDX_ECOLI
Sequence: MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNSSFLHSRKGSEDNCREVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIAEFADL
What is the function of this protein?
Hydrolyzes p-nitrophenyl phosphate (pNPP) in vitro.  Involved in the swarming motility process.
What are the official names of this protein?
Probable phosphatase YcdX.
What is the protein family that this protein belongs to?
Belongs to the PHP family.
Protein: LEUD_MYCSS
Sequence: MEAFRTHTGIGVPLRRSNVDTDQIIPAVYLKRVTRTGFEDGLFAAWRNDPSFVLNLPPFDRGSVLVAGPDFGTGSSREHAVWALMDYGFRVVISSRFADIFRGNAGKAGLLAAEVNQNDVELLWKLIEQNPGLEITVNLQDRNIIAGTVMVPFTIDDYTAWRLLEGLDDIGLTLRKQSEIEDYERRRPSWKPRTLPV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: RL7A_NATPD
Sequence: MSVYVDFDVPADLEDDALEALEVARDTGSVKKGTNETTKAVERGNAELVFVAEDVSPEEVVMHLPEIATEKEIPYVFVGTQDDIGHAAGLQVGSAAAAIVDAGEANGEVEDIAEKVEELQ
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYTIP_HUMAN
Sequence: MSLQRLLQHSSNGNLADFCAGPAYSSYSTLTGSLTMDDNRRIQMLADTVATLPRGRKQLALTRSSSLSDFSWSQRKLVTVEKQDNETFGFEIQSYRPQNQNACSSEMFTLICKIQEDSPAHCAGLQAGDVLANINGVSTEGFTYKQVVDLIRSSGNLLTIETLNGTMILKRTELEAKLQVLKQTLKQKWVEYRSLQLQEHRLLHGDAANCPSLENMDLDELSLFGPLPGPGPALVDRNRLSSESSCKSWLSSMTMDSEDGYQTCVSEDSSRGAFSRQTSTDDECFIPKEGDDFLRRSSSRRNRSISNTSSGSMSPLWEGNLSSMFGTLPRKSRKGSVRKQLLKFIPGLHRAVEEEESRF
What is the function of this protein?
By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.
What are the official names of this protein?
Cytohesin-interacting protein, Cytohesin binder and regulator, CYBR, Cytohesin-associated scaffolding protein, CASP, Cytohesin-binding protein HE, Cbp HE, Pleckstrin homology Sec7 and coiled-coil domains-binding protein.
What are the subcellular locations of this protein?
Cytoplasm. Early endosome. Note=Recruited from the cytosol to endosomes by SNX27.
Protein: PNP_CHLTR
Sequence: MAFETFSVALDKDKTLIFETGKIARQASGAVLVKMNETWVFSSACAASLSEAVDFLPFRVDYQEKFSSAGRTSGGFLKREGRPSEREILVSRLMDRSLRPSFPNRLMQDIQVLSYVWSYDGKTLPDPLAICGASAALAISEVPQNCIVAGVRVGLVGGKWVINPTRDELSASKLDLVMAGTASAVLMIEGHCDFLTEEQVLEAIAFGQTYIAKICDAIEAWQKAIGKQKNFSAVLDMPEDVQNVVSDFIREKFEKALSFRDKEALEQASKELEESVIANLVQEENSDFSLLNVKAAFKTAKSNQMRALIQDLGIRVDGRTTTEIRPISIETPFLPRTHGSCLFTRGETQSMAVCTLGGENMAQRFEDLNGDGAARFYLQYFFPPFSVGEVGRIGSPGRREIGHGKLAEKALSHVLPETSRFPYIIRLESNITESNGSSSMASVCGGCLALMDAGVPIKAPVAGIAMGLILDRDQAIILSDISGIEDHLGDMDFKVAGTAKGITAFQMDIKIEGITHKIMEQALAQAKQGRSHILNLMTQVLASPKGTVSKYAPRIETMQINTSKIATVIGPGGKQIRQIIERSGAQVDINDDGVINIAASTQESINKAKELIEGLTGEVEVGKVYNGRVTSIATFGVFVEVLPGKEGLCHISELSKQKVDNISDFVKEGDKLAVKLLSINEKGQLKLSHKATLED
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOP2_CANAX
Sequence: MSESESDYFTDGSEDDFVPTSKKSTKKNASSKSKQPLGDATNSTVSSSRSSTPKPTNASETYQKLSQLEHILKRPDTYIGSVEKTKTEMWCFDAETESMVFKEVTIVPGLYKIFDEILVNAADNKIRDPSMKNIRVKIDAENNIIEVMNDGKGIPIEMHTKENMYIPELIFGNLLTSSNYDDDQKKVTGGRNGFGAKLCNIFSTQFEVETADLNMGKLYKQSWTNNMSNVSKPKITTLRTKKEYTKITFRPDLSKFDMDCLDNDLLSVLRRRVYDLCGTVKNCNIYLNDKRLNISSFKGYVEMYVKAIKERSPEPEPQDGTIKNFTTIVHEVFNDRWEVAFAVSDGSFNQVSFVNSIATTSGGTHVKYVSDQIINKLVETLSKKEKGKKKLMIKPQEVRDNMFLFINCLIENPAFTSQTKEQLTTKVSQFGGKDKFVANDNLINRILKTSIVDKIRAIANANEDKALQKADGSRKSRIKGQVNLVDANKAGTKDGHNCTLILTEGLSAMNLAVAGLSVVGRDYYGCFPLRGKLLNVREASADQISKNAEINSLKQIIGLQHKKVYTAENIKSLRYGHIMIMTDQDQDGSHIKGLIINFLETSFPGLLDIPGFLLEFITPIVKVTVKARGAGGKRVIPFYTMPEFEHWRDTEGKQCRWTQKYYKGLGTSTPMEAREYFTALDRHLKRFHALQGEDKDYIDLAFSKKKADERKEWLQGFLPGTHLDPEITEIPISDFINKEFILFSMSDNVRSIPSVLDGFKPGQRKVLYGCFKKKLRSEIKVAQLAGYVSENTGYHHGEQSLVQTIIGLAQNFVGSNNINVLKPNGSFGSRAAGGKDFSAARYIFTELSEITRKIFNPLDDPLYTYVQDDEQTVEPEWYLPVLPMILVNGAEGIGTGWSTNIPSYNPKDLVTNIRRLMNGEELQEMTPWYKGWGGDLEPMGPQKFKVSGRIEQIDSNTVEITEIPVKTWTNNVKEFLLSGFGNEKTQPWIKDMEEHHTTSIRFVVKLTDAEMQKSLRIGLLERFKLVSSLSLANMVAFDPMGRIKKYNDVLEIIKDFYYVRLEYYQKRKDYMTDNLQNQLLMLSEQARFIKMIIEKQLSVANKKKKQLVALLEEHNFTKFSKDGKPIKSSEELLTGDDADEEEETQEQEGDEDVGNTSVANIQEGEPEQAAHVPETIYSSYDYLLGMAIWSLTYERFMRIMQQRDQKEAELNALLSKSAKDLWNQDLDEFLAEFDKFLLRDEQERESLASNGKKKSTKRRAKATATKDQPNNKKVKVEPKEKKSTSAKPIVKKEASNEPQASSSSKPKEKDDILSFFSSSSSSAKKTTKPSGRATSNKEIETITLFSDDDDDEDIFNLNSSSSTKVKKEAKSRSATPAAEKSKKSKSSGKQSILDELEDLEILGNFDKPEPKERRTRETASTTKRNTKKKPVIIDSDDEDEDEEDDIVMSDGDDDDDFIVDE
What is the function of this protein?
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands.  Topoisomerase II makes double-strand breaks.
What are the official names of this protein?
DNA topoisomerase 2, DNA topoisomerase II.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECAM_DICDI
Sequence: MSINKILSSTYKITQRSNNNNILFNGLKINSFSLCNTKTNLFTNKTNINLYNNYSKSSKSGKKSKKDEDDEDGEIETSKTSKKSASSSSMENVLKELEKSFGKGTLMKLGSQFSTQKVEVIPSGSMGLDIALGVGGLPKGRVTEIFGPESSGKTTLALHVIAQAQKAGGNCTFIDAEHALNPQWAARLGVNLDELFVSQPDNGEQALEIVDSLLRSKTMSVIVVDSVAALVPRVEIEGEMGDSHLGVQARLMSQALRKLSPTLKDSNCVLIFINQIRMKIGVMFGNPEVTSGGNALKFFSSIRIDIRKVGTVKKGDDIIASQVKAKVVKNKLAPPFKEAIFDIDFQSGINKTGEIIDLAVAEGIIDKMGSWYSYNDIKLDQGREKTKYLLEKTQPNLLVEIENKLRDKLIKSKPLINQQQEEEGNDQTSDEFDIENDDEIIEEDIDDETIKK
What is the function of this protein?
Involved in DNA recombination ability.  Important for survival following exposure to DNA damaging agents.
What are the official names of this protein?
Mitochondrial DNA repair protein recA homolog, Recombinase A homolog.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: HEMO_MOUSE
Sequence: MARTAVALNILVLLGLCWSLAVASPLPTANGRVAEVENGTKPDSDVPEHCLDTWSFDAATMDHNGTMLFFKGEFVWRGHSGTRELISARWKNPITSVDAAFRGPDSVFLIKEDKVWVYPPEKKENGYPKLFQEEFPGIPYPPDAAVECHRGECQSEGVLFFQGNRKWFWDFATRTQKERSWSTVGNCTAALRWLERYYCFQGNKFLRFNPVTGEVPPRYPLDARDYFVSCPGRGHGRPRNGTAHGNSTHPMHSRCSPDPGLTALLSDHRGATYAFTGSHYWRLDSSRDGWHSWPIAHHWPQGPSTVDAAFSWDDKVYLIQGTQVYVFLTKGGNNLVSGYPKRLEKELGSPPGISLETIDAAFSCPGSSRLYVSSGRRLWWLDLKSGAQATWTEVSWPHEKVDGALCLDKSLGPNTCSSNGSSLYFIHGPNLYCYSSIDKLNAAKSLPQPQKVNSILGCSQ
What is the function of this protein?
Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
What are the official names of this protein?
Hemopexin.
What is the protein family that this protein belongs to?
Belongs to the hemopexin family.
What are the subcellular locations of this protein?
Secreted.
Protein: NADK_LIGS1
Sequence: MRVGIFSNNVRRSLEVKAALTRRFLERHFIIDDENPEVVVTIGGDGTLLSAFHKYIDMLDKIRFVGVHTGHLGFYTDWRDDEIDDLVISLQSDNGQSVSYPLLDVFVTYKDSNKRDVFTALNEATIRRISSTMVTDIFIGGEFFERFRGDGLCVSTPTGSTAYNKSLGGAVVHPTLDVLQLTEVSSINNRVFRTLSSPMIIAPKDWITIEPEGAADFILTVDSDSYHKLKIKEIKFKISKKKIHFAKYRHTHFWHRVQTAFIGDEDAD
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_LACTC
Sequence: MVNVVLGSQWGDEGKGKLVDLLVGKYDIVARAAGGNNAGHTIVVKGVKYDFHMLPSGLVNPNCQNLIGNGVVMHVPSFFAELEQLEAKGLTDARERLFISSRAHLVFDFHQRTDKLREAELSGASTDGKNIGTTGKGIGPTYATKASRSGLRVHHLVNDEPGAWEEFETKYRRLVQTRQQRYGDFEYDADAELARYKKYREELKPFVVDSVVFMHNAIRDNKKILVEGANALMLDIDFGTYPYVTSSNTGIGGVCTGLGLPPRVIDEVYGVVKAYTTRVGEGPFPTEQLNESGEKLQNIGAEFGVTTGRKRRCGWLDLVVLKYSTLINGYTSLNITKLDVLDTFKEIPVGVSYTLRGKKLDLFPEDLNVLGKVDVEYVTLPGWEQDITKITEYEDLPENAKKYLKFIEDFVGVPIEWVGTGPARESMVYKQVSK
What is the function of this protein?
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity).
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_FLAJ1
Sequence: MKYLITIVGPTAIGKTALSIALAQHFKCEIVSCDSRQFFKEMTIGTAVPSQEELNSAKHHFIQNKSIFENYTVGDYEKEALAKIEELFEANDFVILIGGSGLYVDAILKGFDEFPEIDPNVRAEVNTNYEKLGIEYLQEQLKNLDPEYYQKITLENPQTLQNPQRMMRFVEVCIGSQKPYSSFLNLKKNNRNFTPILIGLDADREIIYSRINQRVDIMMNEGLLKEAETLYPNKALNALQTVGYRELFSYFDGDFTLPFAIEEIKKNTRRFSKRQLTWFKRNENTKWFDYSTDRNEIIHYIVENLKSSI
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: SCX12_CENNO
Sequence: RDGYPLASNGCKFGCSGLGENNPTCNHVCEKKAGSDYGYCYAWTCYCEHVAEGTVLWGDSGTGPCRS
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.  This toxin binds, in vitro, to sodium channels and inhibits the inactivation of the activated channels.  Seems not toxic to mice, crickets and sweet-water shrimps.
What are the official names of this protein?
Alpha-toxin Cn12.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: CID2A_XENLA
Sequence: MVLESIARVIKVQLPAYLKRLPIPDSIAGFIRLTVSEWLRLLPFLGVLALLGYLAIRPFLLKKKQQKDSLINLKIQKENPKVVNEINIEDLHLAKAAYCRCWRSKTFPVCDGSHNKHNELTGDNVGPLILKKKEV
What is the function of this protein?
Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum.  Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity).
What are the official names of this protein?
CDGSH iron-sulfur domain-containing protein 2A.
What is the protein family that this protein belongs to?
Belongs to the CISD protein family. CISD2 subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein.
Protein: MIND_THEMA
Sequence: MGNVIVVTSGKGGVGKTTITANLGCALAKLGEKVCLIDADIGLKNLDIVLGLENRIVYTMIDVVNGKVSPQEALVKHKMLKNLYLLPASQIATKEMISPNDMKAIVKELIPHFDYIIIDSPAGIERGFRNAVAPAERVLVVTTPELPAISDADRVIGLLENFGFSDEKINVIINRFKPHMVKKGEMLTTDDIKHTLSLEIIAVIPDSEDIIVASNTGIPVSLNGNSRISKNFENLARRIRGEGVPLENDFVTVSKGLIDTLKDFFSKLKRG
What is the function of this protein?
ATPase required for the correct placement of the division site.  Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings (By similarity).
What are the official names of this protein?
Septum site-determining protein MinD, Cell division inhibitor MinD.
What is the protein family that this protein belongs to?
Belongs to the ParA family. MinD subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PUR9_PECCP
Sequence: MQQRRPIRRALLSVSDKAGIVEFAQALSHRGVELLSTGGTARLLADAGLAVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRDQDDAIMAQHDIKPIDIVVVNLYPFAQTVARENCTLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYSAIINEIDANEGSLTYETRFDLAIKAFEHTAAYDSMIANYFGALVPPYHGETDKPSGNFPRTLNLNYIKKQDMRYGENSHQQAAFYIEENIHEASVATSTQLQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPSGVAIGGSILDAYERAYKTDPTSAFGGIIAFNRELDEETAQAIISRQFVEVIIAPSASEAALKVTAAKQNVRVLTSGNWQQRVPGLDFKRVNGGLLIQDRDLGMVDASQLRVVTERQPSEQELRDALFCWKVAKFVKSNAIVYARDNMTIGIGAGQMSRVYSAKIAGIKAGDEGLEVKGSAMASDAFFPFRDGIDAAAAVGITCVIQPGGSIRDDEVIAAANEHGIAMIFTDMRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: Y1420_OCEIH
Sequence: MNGFTNKDFETFNINGLDERMEAIQTRIQPKFQQIGESLAEDLSKKTNNELYLHIAKHARRTVNPPNDTWLAIADNKRGYKKHPHFQVGVFDDHVFIWLALIYELPNKSKIASAYINHFDEVKNLPTSYVVSLDHTKKDAISLTDLNKSHLERFRDVKKAEFLIGKHIEKGDPILANGDELYQFIMDVFEQLLPLYQLAIDSRDE
What are the official names of this protein?
UPF0637 protein OB1420.
What is the protein family that this protein belongs to?
Belongs to the UPF0637 family.
Protein: Y589_METMA
Sequence: MTESDTKITLIGSRLAREGLEFIFKGEMPECKKCRLKNTCLNLEPGRRYKVVRIKSNDIHECFLHDSGVLAVDVSRAPITTSVESRKAVQGAKIMYEPAKCGKRECAEYETCHPEGLIKGDKCKIVEVLESLDSKCEAGISLKKVKLAW
What are the official names of this protein?
UPF0179 protein MM_0589.
What is the protein family that this protein belongs to?
Belongs to the UPF0179 family.
Protein: PSTB_SALTY
Sequence: MSMVETAPSKIQVRDLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMYSLYPEQRAEGEILLDGDNILTNTQDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQRLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NHAA_HELPH
Sequence: MNVKKTENALSLTLKNFIKSESFGGIFLFLNAVLAMVVANSFLKESYFALWHTPFGFQIGDFFIGFSLHNWIDDVLMALFFLMIGLEIKRELLFGELSSFKKASFPVIAAIGGMIAPGLIYFFLNADTPSQHGFGIPMATDIAFALGVIMLLGKRVPTALKVFLITLAVADDLGAIVVIALFYTTNLKFAWLLGALGVVLILAVLNRLNVRSLVPYLLLGVLLWFCVHQSGIHATIAAVILAFMIPVKIPKDSKNVELLELGKRYAETSSGALLTKEQQEILHSIEEKASALQSPLERLEHFLAPISGYFIMPLFAFANAGVSVDSSINLEVDKVLLGVILGLCLGKPLGIFLITFISEKLKITARPKGISWWHILGAGLLAGIGFTMSMFISNLAFTSEHKDAMEVAKIAILLGSLISGIIGALYLFALDKRAALKK
What is the function of this protein?
Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.
What are the official names of this protein?
Na(+)/H(+) antiporter NhaA, Sodium/proton antiporter NhaA.
What is the protein family that this protein belongs to?
Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLD_CHLPN
Sequence: MLLRGIPAAEKILQRLKEEISQSPTSPGLAVVLIGNDPASEVYVGMKVKKATEIGIISKAHKLPSDSTLSSVLKLIERLNQDPSIHGILVQLPLPKHLDSEVILQAISPDKDVDGLHPVNMGKLLLGNFDGLLPCTPAGIIELLNYYEIPLRGRHAAIVGRSNIVGKPLAALMMQKHPQTNCTVTVLHSQSENLPEILKTADIIIAALGAPLFIKETMVAPHAVIVDVGTTRVPADNAKGYTLLGDVDFNNVVTKCAAITPVPGGVGPMTVAMLMSNTWRCYQNFS
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: HMW3_MYCPN
Sequence: MTDKERAKLAKAYGKLAQKIQKSYPDINVVYGRDAKNKLHALYQDPETGNIFSLEKRKQLPADYPLFELDSDEPISFAPKIIPLTAFDGNNNEVIVQYDQVNNTFYDQDGNVLDVSGYRDGENIPLVDYLNYGGSTASADTTTSEPLSGEGYPDIDAGLPVVDPDATPEQQADQLFGLDPLPQAPDEYQDTTAPPAYDQTFDQATYDQQAYDQNYDPNAYYDQQAYDQSFDQQAYDQAYDANAYNTQNYDQAHDPNAYYDSQAYSDPDQASAVAPIEVAPLQPEPVAPVVEPTAVPIVESAPIVEVTPTVEPTPTPVVETAPVVEAPKVVEPTPTPVVEATPAPKVEPKVVEQPQPTPVTVEVDSPKVEIPKVVTAKVALQVAQPTPVPAVPKVAPQPTPAPVVVQPTAVVQPVVKAEPKVVTPTPAPQVVVTPQVATPKVTPKVVQTTPAVPPVVVQPEVVVQPIIRPTQPEPEWKPSPASVVEPQPCQSACVNNESGAITIHTTNRSLLLEKLASLGHLHDASTRTPLPHERYQLAPPSEYVATKYNEPLFNLPAIRNSWARFTRPTVESTPIASRFTGVTPMAVNYRNPASLNFDSLNSFGAYRSPSSFYPLRRPLELSSLRRNRSSFFNTHRFDLGSNYTSFTPRYRSPLRGGLSQRFPLRSSWSKEF
What is the function of this protein?
Component of the cytoskeleton-like structure which stabilizes the shape of the wall-less mycoplasma.  This cytoskeleton-like network of accessory proteins containing HMW proteins 1 to 5 allows the proper anchoring of cytadhesin proteins in the mycoplasmal membrane at the attachment organelle.  Essential for successful surface parasitism.
What are the official names of this protein?
Cytadherence high molecular weight protein 3, Accessory adhesin protein 3, Cytadherence accessory protein 3.
What are the subcellular locations of this protein?
Cell projection, attachment organelle membrane. Note=Localizes specifically to the attachment membrane.