PharMolix/UniProtQA huggingface dataset:
Protein: AUSB_PENBI
Sequence: MAIGPKPESIIGSYDHPPQAEAQTEVKSAAINGDTSPVSRLKDFATDPWLTSTDQPQPDSTTNVPYSLPDSTQDARILIVGAGYGGLLFAVRLLQSGFTLEDILLVDSAGGFGGTWYWNRYPGLMCDIESYIYMPLLEETKNIPSQKYVSGEELRTHAERIAEKWKLGARTLFRTTVSDLTWDDNKMQWIATASFSSNEKKQGSCTYTINADFAILANGTLSKPKVPDLPGIDDYTGRIFHTARWDYDYTGGSPAIPAMDRLRTKKVGVIGTGSTAVQVIPQLARWAGELTVFQRTPGAVGLQENRETDHAWWRDNVQLAGPEWQRKRCENFNAFITNPYRASLEEEDLVKDGWTKHPSFSVALGGARNLQADFLDLAKKIDKERREIGQQHINSTVRNPATAEALFNPTYGWCKRPCFHQGYFETYNRENVRLVSTPGQGITKFTINGIMWGDKEFELDLIVLATGYDLGSLCPANRARLSIHGRGGLSMSQKWASGPATLHGVMTRGFPNLFFPGTSQAGVTANQSYMFDRAAEHIAYIIQNARPRTAASAVNLKVLVEPSLEAEELWAMETVSRARAFAATKTCSAGSYTISARLGESVDESQMARHMPWGEGMASYVKILEEWRKKGDMDGLEVVYD
What is the function of this protein?
FAD-binding monooxygenase; part of the gene cluster A that mediates the biosynthesis of the fungal meroterpenoid acetoxydehydroaustin (PubMed:29076725).  The first step of the pathway is the synthesis of 3,5-dimethylorsellinic acid by the polyketide synthase ausA (By similarity).  3,5-dimethylorsellinic acid is then prenylated by the polyprenyl transferase ausN (By similarity).  Further epoxidation by the FAD-dependent monooxygenase ausM and cyclization by the probable terpene cyclase ausL lead to the formation of protoaustinoid A (By similarity).  Protoaustinoid A is then oxidized to spiro-lactone preaustinoid A3 by the combined action of the FAD-binding monooxygenases ausB and ausC, and the dioxygenase ausE (By similarity).  Acid-catalyzed keto-rearrangement and ring contraction of the tetraketide portion of preaustinoid A3 by ausJ lead to the formation of preaustinoid A4 (By similarity).  The aldo-keto reductase ausK, with the help of ausH, is involved in the next step by transforming preaustinoid A4 into isoaustinone which is in turn hydroxylated by the P450 monooxygenase ausI to form austinolide (By similarity).  The cytochrome P450 monooxygenase ausG then modifies austinolide to austinol (By similarity).  Austinol is further acetylated to austin by the O-acetyltransferase ausP, which spontaneously changes to dehydroaustin (PubMed:29076725).  The cytochrome P450 monooxygenase then converts dehydroaustin is into 7-dehydrodehydroaustin (PubMed:29076725).  The hydroxylation catalyzed by ausR permits the second O-acetyltransferase ausQ to add an additional acetyl group to the molecule, leading to the formation of acetoxydehydroaustin (PubMed:29076725).  Due to genetic rearrangements of the clusters and the subsequent loss of some enzymes, the end product of the Penicillium brasilianum austinoid biosynthesis clusters is acetoxydehydroaustin (PubMed:29076725).
What are the official names of this protein?
FAD-binding monooxygenase ausB, Austinoid biosynthesis clusters protein B.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.
Protein: UVRC_STAAM
Sequence: MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDKLCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOA_CHLPD
Sequence: MDQTLSSFGNVFAFLALGIVFVAGGYLTARMLRPSRPNPAKNSTYECGEEAVGSAWVKFNIRFYVVALIFIIFDVEVVFLYPWATVFKSLGVFALVEVLVFAGILILGLVYAWVKGDLDWVRPEPKVPQMPVMPDRKAEGGRA
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit A, NADH dehydrogenase I subunit A, NDH-1 subunit A, NUO1.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PQQE_XANC5
Sequence: MSIAPPPLSVLLELTHRCPLACPYCSNPIALAALREEMDTAGWRSLLQQAADMGVLQAHFSGGEPMLRKDLPELVAHARALGLYSNLITSGVAGGEPMLDQLQAAGLEHVQLSVQDVDAAGADRIAGYRNSLSKKREFAAAVRARGLPLTINAVLHRHNAERVPGMIALALEWQAERIEVAHTQYDGWGLRNRAALMPSREQLLATIDAVETARRQLGDRLAIDFVTPDYYARQPKPCMGGWGQRFVNISPRGDVLPCHAAETIDGLRFDNLRERSLADIWNNGEAFVRFRGTAWMPEVCQGCPKREIDWGGCRCQALALSGDAATLDPVCERSPIHAQVRATAEQESASPAPAFIYRRPERPAAATADPLE
What is the function of this protein?
Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
What are the official names of this protein?
PqqA peptide cyclase, Coenzyme PQQ synthesis protein E, Pyrroloquinoline quinone biosynthesis protein E.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. PqqE family.
Protein: YKUU_BACSU
Sequence: MAERMVGKQAPRFEMEAVLASKEFGKVSLEENMKNDKWTVLFFYPMDFTFVCPTEITAMSDRYDEFEDLDAEVIGVSTDTIHTHLAWINTDRKENGLGQLKYPLAADTNHEVSREYGVLIEEEGVALRGLFIINPEGELQYQTVFHNNIGRDVDETLRVLQALQTGGLCPANWKPGQKTL
What is the function of this protein?
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.  Plays a role in cell protection against oxidative stress by detoxifying peroxides.
What are the official names of this protein?
Putative peroxiredoxin YkuU.
What is the protein family that this protein belongs to?
Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_CLOBM
Sequence: MRIDVLTLFPEMFSIFNHSIIGRAIENEFLKINTVNIRDYTINKHKKVDDYPYGGGAGMVMAAQPIVDSIKTVKKENKGKVIFLGPKGKTFNQDLAKELAREEELIFLCGHYEGIDERAYEYIDMEISLGDFVLTGGEMACIPIVDSICRLLDGVLGSSESYEDESFYNGLLEYPQYTRPAIYEGKAVPKVLLSGHHENIKKWRKAKSLIITNKVRPDLFKKYKLTEEDKKILKDFNKKL
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL13_METBF
Sequence: MTVIDANGLILGRLASTVAKQLLSGDEEIYIVNAEKAVISGSRATTLKEYRETRERGSTEFGPYFPKRPDRILKRTIRGMLPYKRARGRDAMSRLKVYVGVPTELKDTETITIADADMRLLSSSKYIELGEVSQKMGSKF
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: GCST_THEP1
Sequence: MKRTPLFEKHVGLGAKMVDFAGWEMPLYYTSIFEEVMAVRKSVGMFDVSHMGEFLVKGPEAVSFIDFLITNDFSSLPDGKAIYSVMCNENGGIIDDLVVYKVSPDEALMVVNAANIEKDFNWIKSHSKNFDVEILNISDTTALIAFQGPEAQETLQELVEDSLEEIAYYSFRKSIVAGVEALVSRTGYTGEDGFELMLEAKDAPKVWDALMNLLRKIDGRPAGLGARDVCRLEATYLLYGQDMDESTNPLEVGLSWVVKLDKDFVGKEALLKAKEKVERKLVALELSGKRIARKGYEVLKNGERVGEITSGNFSPTLGKSIALALVSKSVKVGDQLEVAFPGGKLVEALVVKKPFYRGSVRREV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: NU3M_PAROL
Sequence: MSLLMTIITITALLSTILAIVSFWLPQISPDHEKLSPYECGFDPMGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLPTPLLTFTWATAVLFLLTLGLIYEWIQGGLEWAE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: HEM1_MYCGI
Sequence: MSVLLFGVSHRSAPVSVLEQLSTDESDQAKIIAEVLRSSLVTEAMVLSTCNRVEIYAVVEAFHGGLSVIGQVLSDHSGMSLQDLTKYAYVRYAEAAVEHLFAVASGLDSAVVGEQQVLGQVRRAYASAESNHTVGRTLHELSQRALAVGKRVHSETGIDRAGASVVSVALDVAEKKVGPLAGRSAVVVGAGSMGALAATQLARAGIERIHVVNRSLPRGKRLAENIRGYGIAAEAYPFDHLPPLLTDADIVVSCTGAVRPVVSLADVHRGLAHVREPKDLVICDLGMPRDVDAAVAGLPGVFVIDMDRILREPTAKTATSDADAARSIVATEVANYLAGQRVAEVTPTVTALRQRAADVVEAELLRLDNRLPGLDSSHRDEVANTVRRVVDKLLHAPTVRVKQLASAPGGDSYAEALRELFELDQHAVDAVAGSELGAVSGDELAAPAIDLDLTE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: HIS3_BORPA
Sequence: MNTEPTWMAEVVFDENGLIPAIAQDAETGQILMVAWMNREALAETAATGRAVYWSRSRQRLWRKGEESGHAQDVHELRLDCDGDVILLKVHQNGGIACHTGRASCFYRRLEGTASQAEWITIDPVLKDPELIYK
What is the function of this protein?
Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
What are the official names of this protein?
Phosphoribosyl-AMP cyclohydrolase, PRA-CH.
What is the protein family that this protein belongs to?
Belongs to the PRA-CH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PARMW
Sequence: MPTIQQLIRTERSRLKAKTKSPALKSCPERRGVCTRVYTSTPKKPNSALRKVARVRLTSGFEVTAYIGGVGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGTLDTAGVKDRRQSRSKYGAKTPKE
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: S38A8_XENTR
Sequence: MEELARESISLLGKSGLEGGTPSLSSMGAIFIMLKSALGAGLLNFPWAFNKVGGMHTAIMVELVSLIFLISGLVILGYASSLSKHSTYQGVVKDLCGPAIGKLCGICYIINLFMICVAFLRVVEDQLEKLCDSIHSNNTLYAMSEVSQSWYMDPRFAITVLCLVIILPLSIPKEISFQKYTSILGTLAACYLTVMIIIKYYVMEHPVLIKHEFSSNAASWASMFSVVPTICFGFQCHEACVTIYSSMKNKCLSNWAAVSVVSMLICLLIYSFTGIYGSLTFGEAVAADILMSYPGNDVAVIIARLLFTISIITIYPIILLLGRCVIQEAWLNHREKSLFVTLTYERCVRVVITVLWILVTLLIALFVPDISEVISVIGGISAFFIFIFPGLCLVCAVESEPMNTKAKSCLTAWGAISVVCGAFVFGQSTTIAVMEIIAKF
What is the function of this protein?
Putative sodium-dependent amino acid/proton antiporter.
What are the official names of this protein?
Putative sodium-coupled neutral amino acid transporter 8, Solute carrier family 38 member 8.
What is the protein family that this protein belongs to?
Belongs to the amino acid/polyamine transporter 2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MSHR_PRECO
Sequence: MPVQGSQRRLLGSLNSTPTATPKLGLAANQTGAQCLEVSIPDGLFLSLGLVSLVENVLVVAAIARNRNLHSPMYCFICCLALSDLLVSGSNMLETAVILLLEAGALAARAAVVQQLDNVIDVITCSSMLSSLCFLGAIAMDRYISIFYALRYHSIVTLPRARGVVAAIWVASILFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIAQLHKRQRPAHQGVGLKGAATLTILLGIFFLCWGPFFLHLTLIVLCPQHPTCSCIFKNFNLFLALIICNAIIDPLIYAFRSQELRRTLKKVLLCSW
What is the function of this protein?
Receptor for MSH (alpha, beta and gamma) and ACTH.  The activity of this receptor is mediated by G proteins which activate adenylate cyclase.  Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
What are the official names of this protein?
Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASTC_ECO8A
Sequence: MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAPLPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVGTHGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVSRGSS
What is the function of this protein?
Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate.  Can also act as an acetylornithine aminotransferase.
What are the official names of this protein?
Succinylornithine transaminase, Succinylornithine aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily.
Protein: RIHA_ECO55
Sequence: MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPAFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWTPAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
What is the function of this protein?
Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively.
What are the official names of this protein?
Pyrimidine-specific ribonucleoside hydrolase RihA, Cytidine/uridine-specific hydrolase.
What is the protein family that this protein belongs to?
Belongs to the IUNH family. RihA subfamily.
Protein: EUTC_SALAR
Sequence: MDQKQIEEIVRSVMASMGQDVPQPVAPSTQEGAKPQRAAPTATESCALDLGSAEAKAWIGVENPHRADVLTELRRSTAARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNRYLTRPDMGRRLSQEAIDALKSQCVMNPDVQVVISDGLSTDAITANYEEILPPLLAGLKQAGLKVGTPFFVRYGRVKIEDQIGELLGAKVVILLVGERPGLGQSESLSCYAVYSPRVTTTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: THSA_AERPE
Sequence: MAATGYPVLILKEGTQRTYGREALRANILAARVLAEMLKSSLGPRGLDKMLVDAFGDITVTNDGATIVKEMEIQHPAAKLLVEVAKAQDAEVGDGTTSVVVLAGALLEKAEKLLDENLHPTIIIEGYTKAMEEALRLVDEAAVPVEVEDDSVLRRIAETTLASKFVGTGPERDKIISMVIDAIRTVAEKRPDGGYEVDLDYVKIEKKKGGSLLDSKLVRGIVLDKEVVHPAMPKRVENAKILVLDAPLEVQKPELTTKIRVTDIEKLESFLEEETRMLRDMVEKIAATGANVVITQKGIDEVAQHFLAKKGILAVRRVKRSDIEKVAKATGAKIVTSLRDLKPEYLGYAELVEERKVGEDKMVFIEGAKNPKSVTILLRGANDMLLDEAERNIKDALHGLRNILREPKIVGGGGAVEVELALKLKEFARTVGGKQQLAIEAYAEALETIPTVLAESAGMDALEALLKLRSLHSQGYKFAGVNVLEGKIEEDMTKINVYEPVLVKKQVIKSASEAAISILKIDDVIAAAPPKKKEKKGKTGEEEEEEGGGSKFEF
What is the function of this protein?
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.
What are the official names of this protein?
Thermosome subunit alpha, Chaperonin subunit alpha, Thermosome subunit 1.
What is the protein family that this protein belongs to?
Belongs to the TCP-1 chaperonin family.
Protein: HISZ_BORBR
Sequence: MGNWLLPEGLADVLPAEARRIEELRRELLDLYRTYGFELVAPPLVEYIDSLLSSTGSDLNLRTCKLVDQLSGRTLGVRADMTSQVTRIDAHLLNRAGVTRLCYCGSVLHARPADLLSSRELLQIGAEIYGHAGFEADLEIIQLVMDTLATAGVRNARLDLCHSGVMRAIFDADPQASRHAGDLCTLLREKDVPGLAELASRVDGLGEDTVRALQALATLYGGPEIIARARRELPAVPGMAQALDALQALVDAMPGVTLSVDLADVGGYGYHSGVTFAVYGEDWHDALVRGGRYDDVSRAFGRARPATGFSLDLRKLAAGLTPAEPARAVRAPWGQDPALTDAVRRLRRSGEIVVQVLPGHEQGLDEFVCDRELALQDGAWTVRTL
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_DICNV
Sequence: MSAEIINGKEIAAEIRREIKQETAQFIAATGVRPGLAVILVGNDPASEVYVRNKGIQAEEVGFLSQIYRLPAQTTQAELLAKIVALNNDPQICGILVQLPLPAHLNAEIVLNTIDPNKDVDGFHPLNIGRLWAGEPCSVPCTPLGCSLILKRYFGDSLAGKKALIIGRSNIVGKPMAALLLQQHATVTIAHSKTPDVPALCRQADIVIAAVGQPELVKGDWIKSGAVVLDVGINRIAVGDKTKLVGDVAFESAKEVAAAITPVPGGIGPMTIACLLKNTLTLAKAIQQSGK
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: ROCA_BACAA
Sequence: MVVAYKHEPFTDFSVEANKLAFEEGLKKVESYLGQDYPLIIGGEKITTEDKIVSVNPANKEELVGRVSKASRELAEKAMQVADETFQTWRKSKPEMRADILFRAAAIVRRRKHEFSAILVKEAGKPWNEADADTAEAIDFMEYYGRQMLKLKDGIPVESRPIEYNRFSYIPLGVGVIISPWNFPFAIMAGMTTAALVSGNTVLLKPASTTPVVAAKFMEVLEEAGLPAGVVNFVPGNGSEVGDYLVDHPRTRFISFTGSRDVGIRIYERAAKVNPGQIWLKRVIAEMGGKDTIVVDKEADLELAAKSIVASAFGFSGQKCSACSRAVIHEDVYDHVLNRAVELTKELTVANPAVLGTNMGPVNDQAAFDKVMSYVAIGKEEGRILAGGEGDDSKGWFIQPTIVADVAEDARLMKEEIFGPVVAFCKAKDFDHALAIANNTEYGLTGAVISNNRDHIEKAREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLALHMQAKTTSETL
What are the official names of this protein?
1-pyrroline-5-carboxylate dehydrogenase, P5C dehydrogenase, L-glutamate gamma-semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family. RocA subfamily.
Protein: Y3986_XANOM
Sequence: MLHYAMIFFVIAIIAAVLGFSGIAGAATNIAWILFVVFLILAVISMFRRGKV
What are the official names of this protein?
UPF0391 membrane protein XOO3986.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LPXD_CUPTR
Sequence: MQTPTLGQLATENGAQVVGDPDLAITGLAPLDQAGPGELSFLSNPLYLQQALDAKAGAVIVSAADLERVRAEGKADGRNWLVARNPYVCFARVAQRFDRAANTDARTGIDARATVAPDAVVPASCYIGPNVVIEAGARLGERVRILANGYVGAHAQIGDDALLYANVSVYHHCVVGARAILHSGVVIGADGFGFAPDISASGVEYVKIPQTGRAVLGDDVEVGANTAIDRGAMADTVIEDGCKIDNQVQIAHNVRVGAHTVIAGCAAVSGSTRIGRFCVIGGAANFAGHLTIADRTTVSGGTSITKSITKPGGHFTSVFPFLPHGEWERNAAIVRGLSKLRERVVALERRLRGQAAGSQPSQD
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: GLMU_MYCTU
Sequence: MTFPGDTAVLVLAAGPGTRMRSDTPKVLHTLAGRSMLSHVLHAIAKLAPQRLIVVLGHDHQRIAPLVGELADTLGRTIDVALQDRPLGTGHAVLCGLSALPDDYAGNVVVTSGDTPLLDADTLADLIATHRAVSAAVTVLTTTLDDPFGYGRILRTQDHEVMAIVEQTDATPSQREIREVNAGVYAFDIAALRSALSRLSSNNAQQELYLTDVIAILRSDGQTVHASHVDDSALVAGVNNRVQLAELASELNRRVVAAHQLAGVTVVDPATTWIDVDVTIGRDTVIHPGTQLLGRTQIGGRCVVGPDTTLTDVAVGDGASVVRTHGSSSSIGDGAAVGPFTYLRPGTALGADGKLGAFVEVKNSTIGTGTKVPHLTYVGDADIGEYSNIGASSVFVNYDGTSKRRTTVGSHVRTGSDTMFVAPVTIGDGAYTGAGTVVREDVPPGALAVSAGPQRNIENWVQRKRPGSPAAQASKRASEMACQQPTQPPDADQTP
What is the function of this protein?
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc).  The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
What are the official names of this protein?
Bifunctional protein GlmU.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transferase hexapeptide repeat family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_OENOB
Sequence: MAQITAALVKELREKTSAGIMDAKKALVETNGNMEKAIDVLKERGVAKAAKKADRVAAEGMTDVIEAGNTAAIIELNSETDFVASNEKFLNLLHLTAKVILEHKPADLKAALAIPVEEGTLNDQIVQTSAHTGEKITLRRFNVVEKNDNQTFGVYSHMGGQISVITLLENSDSTTAKDIAMHIAAIAPKYLSREDVPKDVVEHEKSIQMKADDLGNKPDNIKEKIVEGRLGKFLDELALLNQPFVKGEGESVAEYLKKQGATIKSFIRYQVGEGIEKQESNLADEVAKQING
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_LEIMA
Sequence: MVAESKAANPMREIVVKKLCINICVGESGDRLTRASKVLEQLCEQTPVLSRARLTVRTFGIRRNEKIAVHCTVRGKKAEELLEKGLKVKEFELKSYNFADTGSFGFGIDEHIDLGIKYDPSTGIYGMDFYVVLGRRGERVAHRKRKCSRVGHSHHVTKEEAMKWFEKVHDGIIFQAKKKKKMIRRRRR
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y4257_PSEU2
Sequence: MERFFENAMYASRWLLAPIYFGLSLGLLALCLKFFQEIFHVIPNIFSLAEADLILVLLSLIDMALVGGLLVMVMISGYENFVSQLDIDEDKEKLNWLGTMDSSSLKMKVAASIVAISSIHLLRVFMDATNIKPEYLMWYVIIHMTFVISAFAMGYLDKVTKH
What are the official names of this protein?
UPF0114 protein Psyr_4257.
What is the protein family that this protein belongs to?
Belongs to the UPF0114 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.