PharMolix/UniProtQA huggingface dataset:
Protein: IF1_LACP3
Sequence: MAKDDVIEIQGTVTDTLPNAMFKVKLENGAEILAHVSGKIRMHYIRILPGDKVTVELSPYDLTKGRITYRFK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_NOVAD
Sequence: MPSNSPAPDAPLAVVLLSGGLDSMVCAGLAQEQGFRVLALTIDYNQRHRVELDAARAIAARLGVERHVILPLDLRQFGGSALTADIAVPKDGVGDDIPVTYVPARNLIFLSLALAWAEAAGSKDLFIGVNALDYSGYPDCRPEFVAGFEDLARIATKVGSEGGTVTVHAPLQHLKKSEIAREAARLGLEAGDSWSCYDPLPDGRACGVCDSCRLRRAGFEEAGLNDGTRYGGG
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: SYH_MALP2
Sequence: MVIKKPRGTYDLFGEEIEVFNKINDVLKTISNTYNCHEIKTPIFEHKELYIRNIGESSDIVTKEFYDFKDKSDRELALRPENTVGVIRSVVENKLLYTNPFPLKFYYLGPMFRYERPQSGRNRQFYQFGIEFIGVKNILNEIEGILFALDILKKLNITNWKLKVNYIGSIETREKWINSLKKYFNKYKDELSEDSKNRIEKNPLRILDDKVDGSKSFVKSCPKIEEFLTKEEKEESDNFIKCLKTIVNEFEFDSTLVRGLDYYSGPVFEIVSQSNKLTGQSTIIGGGRYTKLTKELGDNDYICFGFALGMERLMLAYRDENQFLSNNSVDVYIASIGSVESELVAMNFANQLRNLNYRVEVNFDLKKIDKQFKNSNKYNPKIILIYGDEDHKNKQVTLKNQKTLENKVIKLNELNNKIKEFFESDK
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF6_PHLPR
Sequence: MSWQTYVDEHLMCEIEGHHLASAAILGHDGTVWAQSADFPQFKPEEITGIMKDFDEPGHLAPTGMFVAAAKYMVIQGEPGAVIRGKKGAGGITIKKTGQALVVGIYDEPMTPGQCNMVVERLGDYLLKQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity).
What are the official names of this protein?
Profilin-6, Pollen allergen Phl p 12, pollen profilin variant 3.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: PAN3_HUMAN
Sequence: MNSGGGLPPPSAAASPSSSSLAAAVAVVAPPGVGGVPGGAAVGVKLKYCRYYAKDKTCFYGEECQFLHEDPAAGAAPGLGLHSNSVPLALAGAPVAGFPPGAVAGGGAGPPPGPKKPDLGDPGTGAAAGGGGSSGGLDGPRLAIPGMDGGALTDTSLTDSYFSTSFIGVNGFGSPVETKYPLMQRMTNSSSSPSLLNDSAKPYSAHDPLTSPASSLFNDFGALNISQRRKPRKYRLGMLEERLVPMGSKARKAKNPIGCLADRCKSGVPINMVWWNRVTENNLQTPNPTASEFIPKGGSTSRLSNVSQSNMSAFSQVFSHPSMGSPATAGLAPGMSLSAGSSPLHSPKITPHTSPAPRRRSHTPNPASYMVPSSASTSVNNPVSQTPSSGQVIQKETVGGTTYFYTDTTPAPLTGMVFPNYHIYPPTAPHVAYMQPKANAPSFFMADELRQELINRHLITMAQIDQADMPAVPTEVDSYHSLFPLEPLPPPNRIQKSSNFGYITSCYKAVNSKDDLPYCLRRIHGFRLVNTKCMVLVDMWKKIQHSNIVTLREVFTTKAFAEPSLVFAYDFHAGGETMMSRHFNDPNADAYFTKRKWGQHEGPLPRQHAGLLPESLIWAYIVQLSSALRTIHTAGLACRVMDPTKILITGKTRLRVNCVGVFDVLTFDNSQNNNPLALMAQYQQADLISLGKVVLALACNSLAGIQRENLQKAMELVTINYSSDLKNLILYLLTDQNRMRSVNDIMPMIGARFYTQLDAAQMRNDVIEEDLAKEVQNGRLFRLLAKLGTINERPEFQKDPTWSETGDRYLLKLFRDHLFHQVTEAGAPWIDLSHIISCLNKLDAGVPEKISLISRDEKSVLVVTYSDLKRCFENTFQELIAAANGQL
What is the function of this protein?
Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover.  PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP).  PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex.  Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.  PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
What are the official names of this protein?
PAN2-PAN3 deadenylation complex subunit PAN3, PAB1P-dependent poly(A)-specific ribonuclease, Poly(A)-nuclease deadenylation complex subunit 3, PAN deadenylation complex subunit 3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. PAN3 family.
Protein: Y648_CITK8
Sequence: MSKSLNIIWQYLRAFVLIYACLYAGIFIASLLPITIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFLVVSWSSHIVHGERKVLGQKGSKK
What are the official names of this protein?
UPF0299 membrane protein CKO_00648.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TFS2_DROME
Sequence: MSVEEEVFRIQKKMSKMASDGTGQDQALDLLKALQTLNINLDILTKTRIGMTVNELRKSSKDDEVIALAKTLIKNWKRFLASPAPTTPNNSSAKEGSSNNSSASKSTSAAKSSSSISGKDKSSSSSSSKDKEKKGSTSSSQTSFPSGGMTDAVRIKCREMLATALKIGEVPEGCGEPEEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQTRSADEPMTTFVMCNECGNRWKFC
What is the function of this protein?
Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.  The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes.  Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
What are the official names of this protein?
Transcription elongation factor S-II, RNA polymerase II elongation factor DMS-II, TFIIS.
What is the protein family that this protein belongs to?
Belongs to the TFS-II family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TM181_HUMAN
Sequence: MGAAPSPTQASSRGGGPGPPAPTRAVSSSSRARGGALSALGPSPARPLTTSPAPAPPPRSRPARQQPDPQCWEKRGGAGGDTKGGAAGPGPGRLRGMDAEYPAFEPPLCSELKHLCRRLREAYRELKEDLTPFKDDRYYRLAPMRLYTLSKRHFVLVFVVFFICFGLTIFVGIRGPKVIQTSAANFSLNNSKKLKPIQILSNPLSTYNQQLWLTCVVELDQSKETSIKTSFPMTVKVDGVAQDGTTMYIHNKVHNRTRTLTCAGKCAEIIVAHLGYLNYTQYTVIVGFEHLKLPIKGMNFTWKTYNPAFSRLEIWFRFFFVVLTFIVTCLFAHSLRKFSMRDWGIEQKWMSVLLPLLLLYNDPFFPLSFLVNSWLPGMLDDLFQSMFLCALLLFWLCVYHGIRVQGERKCLTFYLPKFFIVGLLWLASVTLGIWQTVNELHDPMYQYRVDTGNFQGMKVFFMVVAAVYILYLLFLIVRACSELRHMPYVDLRLKFLTALTFVVLVISIAILYLRFGAQVLQDNFVAELSTHYQNSAEFLSFYGLLNFYLYTLAFVYSPSKNALYESQLKDNPAFSMLNDSDDDVIYGSDYEEMPLQNGQAIRAKYKEESDSD
What is the function of this protein?
Mediates action of cytolethal distending toxins (CDT), which are secreted by many pathogenic bacteria.  Expression level of TMEM181 is rate-limiting for intoxication.
What are the official names of this protein?
Transmembrane protein 181.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RL30_HALMA
Sequence: MHALVQLRGEVNMHTDIQDTLEMLNIHHVNHCTLVPETDAYRGMVAKVNDFVAFGEPSQETLETVLATRAEPLEGDADVDDEWVAEHTDYDDISGLAFALLSEETTLREQGLSPTLRLHPPRGGHDGVKHPVKEGGQLGKHDTEGIDDLLEAMR
What is the function of this protein?
This is one of 5 proteins that mediate the attachment of the 5S rRNA onto the large ribosomal subunit, stabilizing the orientation of adjacent RNA domains.
What are the official names of this protein?
50S ribosomal protein L30, Hl16, Hl20, Hmal30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: TSAD_ONYPE
Sequence: MNILSIETSCDETSCAVTQNGKKVLSNVVFSQIKDHQIFGGVVPEIASRKHIQFMTLVLQQALKEANLTPQEIDLVAVTQGPGLVGSLLVGINAANVFAYTYQKPLLGVNHLLGHIYSAQIEHEINFPALVLLVSGGHTDLFYLTDHLQIKPLGTTLDDAVGEVYDKIAKNLNLPYPGGPLIDQLAQQGKDTYHLVRPYLKNDNLNFSFSGLKSTLVNLVMKQNLKDINIPDL
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction (By similarity).
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOBD_SALPC
Sequence: MTITDLLLILFIAALLAYALYDQFIMPRRNGPTLLSIALLRRGRVDSVIFVGLVAILIYNNVTSHGAQMTTWLLSALALMGFYIFWIRTPRIIFKQRGFFFANVWIEYNRIKEMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLIENQ
What are the official names of this protein?
UPF0266 membrane protein YobD.
What is the protein family that this protein belongs to?
Belongs to the UPF0266 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: NNRD_CANAW
Sequence: MLRNKSQKELLHLSRQLIQPLLPNFHKGQAGKIVVIGGNEDYTGAPFFASHSAALVGADLSHVICEKAAGPVIKSYSPDLMIHPYLMDLDNPHLNLNNSELEKLKNLPIDEIIKTNDNAVLNKLIDELILPKVTSLLNRIDIVVVGPGFGRDPLMLKSLIRIIEEVKVLNLPIILDADSLYLVSLSPKIIANYPKAIITPNVVEFQRIAKALSIDVDLSESNKDKLIDQTIEVSRKLGDIIVFRKGEHDLIVKSSKFLINEITGSNKRVGGQGDTLTGAIATLVNWSNNYILRLWDNQVDLDQEDANLLACFAASSVVRNASSKAFNKYGRSMQTSNVHEYLHESFTELFGDSIFRTSNI
What is the function of this protein?
Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP.  Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
What are the official names of this protein?
ATP-dependent (S)-NAD(P)H-hydrate dehydratase, ATP-dependent NAD(P)HX dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NnrD/CARKD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GAT22_ARATH
Sequence: MGSNFHYTIDLNEDQNHQPFFASLGSSLHHHLQQQQQQQQHFHHQASSNPSSLMSPSLSYFPFLINSRQDQVYVGYNNNTFHDVLDTHISQPLETKNFVSDGGSSSSDQMVPKKETRLKLTIKKKDNHQDQTDLPQSPIKDMTGTNSLKWISSKVRLMKKKKAIITTSDSSKQHTNNDQSSNLSNSERQNGYNNDCVIRICSDCNTTKTPLWRSGPRGPKSLCNACGIRQRKARRAAMATATATAVSGVSPPVMKKKMQNKNKISNGVYKILSPLPLKVNTCKRMITLEETALAEDLETQSNSTMLSSSDNIYFDDLALLLSKSSAYQQVFPQDEKEAAILLMALSHGMVHG
What is the function of this protein?
Transcriptional regulator that specifically binds 5'-GATA-3' or 5'-GAT-3' motifs within gene promoters (PubMed:22102866, PubMed:25077795).  Involved in the modulation of chloroplast development, growth and division in a cytokinin-dependent manner (PubMed:22102866, PubMed:22811435).  Repressor of the gibberellic acid (GA) signaling pathway that regulates flowering and modulates greening, in a SOC1-dependent manner (PubMed:20844019, PubMed:23739688, PubMed:25077795).  Prevents the accumulation of SOC1 during flowering (PubMed:23739688).  Promotes chlorophyll biosynthesis throughout the plant, by regulating chlorophyll biosynthetic genes (e. g.  HEMA1 and GUN4) and chloroplast localized glutamate synthase (e. g.  GLU1) (PubMed:18417639, PubMed:20844019, PubMed:21453984, PubMed:22102866, PubMed:23878229, PubMed:25077795).  Involved in the regulation of sugar-sensing genes (e. g.  HXK1, HXK2, STP13 and PLT6) (PubMed:18417639).  Regulator of germination, senescence, elongation growth and flowering time (PubMed:20844019, PubMed:22102866, PubMed:23878229).  Influences also leaf starch content (PubMed:22102866).
What are the official names of this protein?
Putative GATA transcription factor 22, Protein CYTOKININ-RESPONSIVE GATA FACTOR 1, Protein GNC-LIKE, AtGNL.
What is the protein family that this protein belongs to?
Belongs to the type IV zinc-finger family. Class B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CHRD1_DANRE
Sequence: MSLMCYNKGCGQRFDLEKNSDDACTYHPGVPVFHDALKGWSCCKRRTTDFSDFLSIAGCTKGPHNQEKPAEPVKPEVKSSLDKNDVKPKYDEFIIQAPKPLESIQRPSPDEPFSILQSKISPSLKQALEKLKLTEENAHEIKEEDSDEIKIGTSCKNGGCCKTFAGQASDDETCLYHAGVPIFHEGMKYWSCCKRKTSDFNTFLSQEGCTRGKHQWKKKDAGKKVVPCRFDWHQTGSQVIISIYAKNSVPELSLVEGNSTVLKIHIIFEGEKEFEKQISLWGVIDPSKSLVNMMATKIEIVLKKAEPMSWARLDLPPVAPPKEKEKEKDVDSEDECDDDED
What is the function of this protein?
Regulates centrosome duplication.
What are the official names of this protein?
Cysteine and histidine-rich domain-containing protein 1, CHORD domain-containing protein 1, Morgana.
Protein: LEXA_LEIXX
Sequence: MSNENQTPRGTRRRKNLSEKQLAILDVIQRSVSQRGYPPSMREIGDAVGLSSLSSVTHQLNQLELSGYLRRDPNRPRALEILIDLPSAAAPDFESQTPVGDAAMVPLVGRIAAGVPITAEQQVEEVFPLPRQLVGNGELFMLKVVGESMIDAAICDGDWVVVRAQNTAENGDIVAAMLDEEATVKVFRQRDGHTWLLPRNSNFEPILGDFSQILGKVVAVLRAV
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: PEPX_STRZJ
Sequence: MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRFFFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDVFRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLATFSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKASDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDYFLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVKADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGGYPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYLLNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSIDFRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQAIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSSTNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKGYLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNTDYHLTVDLAQSMLTLPC
What is the function of this protein?
Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.
What are the official names of this protein?
Xaa-Pro dipeptidyl-peptidase, X-Pro dipeptidyl-peptidase, X-prolyl-dipeptidyl aminopeptidase, X-PDAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F219A_DANRE
Sequence: MMEEIDRFQVPPVNPEMKLLQDPAETSTIENETAPREPESVAINYKPSPLQVKIEKQRELARKGSVKNGTVGSPVNQQPKKNNVMARTRLVVPNKGYSSLDQSPDEKPLVALDTDSDDDFDMSRYSSSGYSSAEQINQDLNIQLLKDGYRLDEIPDDEDLDLIPPKSVNPTCMCCQATSSTACQIQ
What are the official names of this protein?
Protein FAM219A.
What is the protein family that this protein belongs to?
Belongs to the FAM219 family.
Protein: MDM10_YEAS1
Sequence: MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIHLQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLENFMRNSTDIPLQDATETYRQLQPNLNFSVSSGNTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKRLNPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTPSKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFGHISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPISDELVDINSNSRATKLLHENVPDLNLAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRKIDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTRGFQESLSDDEKNDNAISISATDTENGNIPVFPTKFGIQFQYST
What is the function of this protein?
Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria.  Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange.  MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex).  Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins.  Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins.  May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway.  Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
What are the official names of this protein?
Mitochondrial distribution and morphology protein 10, Mitochondrial inheritance component MDM10.
What is the protein family that this protein belongs to?
Belongs to the MDM10 family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Multi-pass membrane protein. Note=The ERMES/MDM complex localizes to a few discrete foci (around 10 per single cell), that represent mitochondria- endoplasmic reticulum junctions. These foci are often found next to mtDNA nucleoids.
Protein: YJB6_SCHPO
Sequence: MKGFFLIAGFLLFARALCASWNVEEGTLQLSSQDLESENAYDLKFSQIQSSTVYELTGDETLNLKFTCILNGTGAIPHQAHLLLSDTEHPTLAVIYPASVSQGGVASLELRLFDIPTSLLRSDSTLTAKLLVASFGETIPFSLPLGQLSINVPPSLYHKAEFSPLDELSPKEVILHTFSPPPKRANYFLSICFSVSVVVSLIGLLGVWQKLLPKSNVYSVSSSSFARTFGFASLAVAEILLFIYWTSLSIFQFGAYAAGVAIMCGIAAKSL
What are the official names of this protein?
Uncharacterized protein C553.06.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RNFC_HAEI8
Sequence: MADVLSRFNSGKLWDFKGGIHPPEMKSQSNSQPLRHLPLGTDFYIPLKQHLGTTGNLLIKEGDYVLKGQALTKGDGLRMLPVHAPTSGTIKSIKPYVATHPSGLDEPTIHLQADGLDQWIERNPIDDFSTLSPEQLIHKIYQAGIAGLGGAVFPTAAKIQSAEQKVKLLIINGAECEPYITCDDRLMRERADEIIKGIRILRYILHPEKVVIAIEDNKPEAISAIRTALQGANDISIRVIPTKYPSGATKQLIYLLTGIEVPSGARSSSIGVLMQNVGTMFAIKRAIINDEPLIERVVTLTGNKIAEKGNYWVRLGTPISQILSDAGYQFDKHFPIFAGGPMMGLELPNLNAPVTKLVNCLLAPDYLEYAEPEAEQACIRCSSCSDACPVNLMPQQLYWFARSEDHKKSEEYALKDCIECGICAYVCPSHIPLIQYFRQEKAKIWQIKEKQKKSDEAKIRFEAKQARMEREEQERKARSQRAAQARREELAQTKGEDPVKAALERLKAKKANETEPTQIKTLTSEKGEVLPDNTDLMAQRKARRLARQQAASQVENQEQQTQPTDAKKAAVAAAIARAKAKKLAQTNSTSEAISNSQTAENEVEKTKSAVEKTEENSTALDPKKAAVAAAIARAKAKKLAQANSTSEAISNSQTAENEVEKQIVR
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit C, Rnf electron transport complex subunit C.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: KDSD_ECOL6
Sequence: MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEKMFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIAISNSGESSEITALIPVLKRLHVPLICITGCPESSMARAADVHLCVKVAKEACPLGLAPTSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPHVKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRRLSIADVMTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV
What is the function of this protein?
Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO), a unique 8-carbon sugar component of lipopolysaccharides (LPSs).  Catalyzes the reversible aldol-ketol isomerization between D-ribulose 5-phosphate (Ru5P) and D-arabinose 5-phosphate (A5P) (By similarity).
What are the official names of this protein?
Arabinose 5-phosphate isomerase KdsD, API, L-API.
What is the protein family that this protein belongs to?
Belongs to the SIS family. GutQ/KpsF subfamily.
Protein: CXAT3_CONMI
Sequence: MPKLEMMLLVLLILPLSYFSAAGGQVVQGDWRGDGLARYLQRGDRDAQGCQVVTPGSKWGRCCLNRVCGPMCCPASHCYCIYHRGRGHGCSC
What is the function of this protein?
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them.  This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes (By similarity).
What are the official names of this protein?
Alpha-conotoxin-like Ml20.3.
What is the protein family that this protein belongs to?
Belongs to the conotoxin D superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DCL1_ASPFU
Sequence: MAEQISLVDVSSSVSLRGEDSSNVALLRDVFLPDVAASDPAESSVDVQDEHSSDDSDNENEVFPKQNDFSQRRRIQNAQFEALLSKCTDADSNEAFDRAPIALSDGELSIAHLVKKQDLGNGMLDPREYQIELFERAKTQNTIAVLDTGSGKTLIAVLLLRHTILNELDDRANGKTHRVSFFLVDSVTLAYQQAAVLRNNIDQNVAHFFGAMGTDLWDKRTWDKHLQRNMVIVCTAEILNQCLLNSYVRMDQINLLIFDEAHHAKKDHPYARIIRDSYFKAQPSQRPRVFGMTASPIDTKGDITEAATRLETFLDSRIATTSKITLLREVVSRPIEKVWAYNRLEPPFATELYKLMDTRYGNIKVLEGVYRFAWNASSELGKWCSDRAWWHALADDVLPKLEGNINKLIESNTMKAEHGAVFKDIIRIREASETVKNYFFTDPELPGELSPKVQRLRMELSKHFNDTTGTKCIVFTQKRYTAKILNELFTVLNIPNLRPGVLIGVRPGDIGGMNITFRQQFLALVKFRTGEINCLFATSVAEEGLDIPDCNLVIRFDLYRTLIQYVQSRGRARHCTSTYAIMVEKDNAEHEGRLKEIREAENIMRRFCEILPEDRILHGNDHDLDSFLQEEEGRRTFTVKSTGAKLTYHSAIAILARYASSLQYEKETVPQVTYVVTIASNAYVCEVILPEKSPIRGLTGSPAMRKAVAKRSAAFDTCLLLRKNRLLDGYFNSIYHRRLPAMRNAKLAITCKRTNAYDMLLKPSIWAKQRTTPTETFYGIHMSLLPSKPLSRDHRPILLLTREKLPEFPAFSIYLDEDVETKVLSYPLKHGLQISVDKLQSLTVFTLRIFRDIFHKVYEHEVQKMPYWLAPAEAIDGRGSGKNPRDCIDWDTVSFVHNNDEITFTRNLNPESLVNRFIFDNWDGRFRYFTVAVADTLQPSDPPPPSVPRRRYMNNIMNYTLSLSKNSRARFLSSCDWNQPVLQAELVRLRRNLLDKMTTQEKEMQTECFICAEPLRISALPPSIVSTCLAFPAIISRLDSYLIALEACDELELVIRPDFALEAFTKDSDNTEEHRGQQIHFQRGMGKNYERLEFLGDCFLKMATSIALFSQNPNDDEFDYHVNRMCLICNKNLFNTAIKKQIYRYIRSRGFSRHIWYPDGLTLLHGKDHSTKLLSEGKHALGEKTIADVCEALIGASLLSGGPEHRFDMATKAVSALVDSPSHRVSCWKEYITLYTLPKYQTEKHRGSEDDLARHVEEELGYHFTYPRLLASAITHPSLPSTWGYRVPCYQRLEFLGDSLLDMVCVEDLFRRFPDRDPQWLSEHKMAMVSNKFLGALSVKLGFHRRIMAFSNPLQAQITHYVEEIETAQAESQGAVDYWVVAKDPPKCLPDMVEAYLGAIFVDSKFDFQVIEAFFERQIKPFFEDMSIYDTFANKHPTTFLHNKLTNEYGCTNYCLKAGELPTIDGAPATVLAAVIVHGNVISEARSSSSRYAKITASEKALAVLDGLLPSEFCQKYRCDCKETKNSSSVVEIGTAI
What is the function of this protein?
Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway.  Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS).  Part of a broad host defense response against viral infection and transposons (By similarity).
What are the official names of this protein?
Dicer-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Dicer subfamily.
Protein: SUBT_BACS9
Sequence: MKRSGKIFTTAMLAVTLMMPAMGVSANEGNAAAEGNEKFRVLVDSVDQKNLKNAKQQYGVHWDFAGEGFTTDMNEKQFNALKKNKNLTVEKVPELEIATATDKPEALYNAMAASQSTPWGIKAIYNNSSITQTSGGGGINIAVLDTGVNTNHPDLRNNVEQCKDFTVGTTYTNNSCTDRQGHGTHVAGSALADGGTGNGVYGVAPDADLWAYKVLGDDGSGYADDIAAAIRHAGDQATALNTKVVINMSLGSSGESSLITNAVNYSYNKGVLIIAAAGNSGPYQGSIGYPGALVNAVAVAALENKVENGTYRVADFSSRGYSWTDGDYAIQKGDVEISAPGAAIYSTWFDGGYATISGTSMASPHAAGLAAKIWAQYPSASNVDVRGELQYRAYENDILSGYYAGYGDDFASGFGFATVQ
What is the function of this protein?
Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides.
What are the official names of this protein?
Subtilisin.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.