PharMolix/UniProtQA huggingface dataset:
Protein: NSMA3_DANRE
Sequence: MAASALQQPSYLLANLKADWTNKPLHQRCHELCKIIDDYPAKELHAIFPWLVECVFGSLDGILTGWNLRFLQARSAEYSIAMEFLDPSGPMMKLVYKLQAEEYKYEFPISYLPGPIKSSIHAGVLPDCPLFHNKIQFPMSGLLFLNPFEYYMFNFASSLIAPKNYPQGQHGSSSDSAYFVLVDTYLKYFLPTEGNVPPSPFSDTRGTVASPAPRSTNVPYVGYGGHSTSLLKRHITHQSSVNADPAAQEIWRSETLLQVFVEMWLHHYSLEMYQKLQSPQVKEPFMPSEEHVLVVRLLVKHLHTFSSSLKPESISSSPSAHSHSSPLEELKRVVVQRFVQQKLYVFLQHCFGHWPLDASFRAVLETWLSYIQPWRYTGDKNNTQTDGPNRTVPDKWASFVQENLLLYTKLFQGFLNRAMRTDLVNAKNALMVFRVAKVFAQPSLSEMIQKGEQLFLEPEHAILQRHNRVFLTPSHGGSFLSARQPMGTDNVFKVKSHVYSLEGQDCQYNLMFGPDQRKNVLKLIQIIAQARQTAKRISDHSTEMAANNSFLSWFGVGSPDHNSTFTGGEMDEMGGEGVKKTHEFLDKALDYLCQIFRLNAGQLSQLISNVASVDNNGASKQLPDCIPSENGLVLTDLGRLQIINGLRRFEIEYQGDPELQPIRSYENAFLVRLLFQISSFINERLGEHMEVLCSRQDFLGSVGRHYLSSSSAVVEQRRKSPVTRQMRDRPQRARLSLRALASYRTLLTLLLLYMLFALLSFGLFSSTGLILIISFLYELLSNFFHEKLKTH
What is the function of this protein?
Catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide.  It has a relevant role in the homeostasis of membrane sphingolipids, thereby influencing membrane integrity, and endoplasmic reticulum organization and function.  May sensitize cells to DNA damage-induced apoptosis.
What are the official names of this protein?
Sphingomyelin phosphodiesterase 4, Neutral sphingomyelinase 3, nSMase-3, nSMase3, Neutral sphingomyelinase III.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Nucleus envelope. Cell membrane, sarcolemma.
Protein: HIS7_CHLPB
Sequence: MPQKKHNRVRSAKVLRKTSETDISVEVDLDGSGSSTVDSGVTFLDHMLTNFSKHSGIDIALRCKGDTGIDDHHSVEDIAIVMGSAILEALGDKKGIHRYGWAIIPMDEALARCSLDLGGRSYCVFHAPFSRAEINGFSTEMVEHFFVSLSRTLQANLHLRVLEGSNTHHKIEALFKAFAYAMKQAVHIIGTDIPSTKGMI
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBCX_PICPA
Sequence: MSAEKRLLQEYRSILKEQRQKGSASTLSSNGILDLKPVSEDNFYKWTAKLKGPTDTGYQDAFWELQIDIPSNYPTQPPKFTFIVSDDIPRNRRQRQTNQIQDDDEFEGAEKEVLRHCYRMPHPNIAFNTGEICLDILQAKWTPAWTLSSALTAIVLLLNDPEPLSPLDIDMANLMKINDLKAYNSLIEYYVGRYSIEEEVYILN
What is the function of this protein?
Catalyzes the covalent attachment of ubiquitin to other proteins.  Essential for peroxisome biogenesis.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2-24 kDa, E2 ubiquitin-conjugating enzyme PEX4, Peroxin-4, Ubiquitin carrier protein, Ubiquitin-protein ligase.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RL6_KOCRD
Sequence: MSRIGRLPISVPAGVEVSVDGSAVSVKGPKGTLTHTVSAPITVVVEDGTVQVSRPNDERESRSLHGLTRSLIANMIQGVSEGYTKQLEIVGTGYRVQAKGADLEFALGYSHPVPFSAPDGITLSVEGNNKVTVSGIDKQQVGQVAAKIRSLRLPDPYKGKGVRYAGEQIRRKAGKAGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: DHMA_MYCMM
Sequence: MDVVRTPDARFQNLVGYPFAAHYVDVAATDTPHLRMHYIDEGPADGPPIVLLHGEPTWSYLYRTMIPPLAAGGYRVLAPDLIGFGRSDKPTRIADYTYLRHVEWVKSWFEELRLAEATLFVQDWGSLIGLRVAAEHGDAIARLVVANGFLPTARGRTPTAFHIWRAFARYSPVLPAGRLVAAGTVRKVPPAVRAGYDAPFPDKSYQAGARAFPQLVPISPDDPAVAANRAAWDALGRWEKPFLAIFGERDPLLGRADRPLIKHIPGAAGQPHARINANHFIQEDSGPELAERIISWQ
What is the function of this protein?
Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons.
What are the official names of this protein?
Haloalkane dehalogenase.
What is the protein family that this protein belongs to?
Belongs to the haloalkane dehalogenase family. Type 1 subfamily.
Protein: NADD_CLAMS
Sequence: MTTAATPRLRIGVMGGTFDPIHNGHLVAASEVQQHLQLDEVIFVPTGQPWQKQTVTDGEHRYLMTVIATAANPRFTVSRVDIDRAGTTYTIDTLRDIRRTHPDAELFFITGADAIQQILGWKDVAELWDLAHFVAVTRPGHDLTESGLPHADVRLLEVPALAISSTDCRARVGRGFPVWYLVPDGVVQYISKHHLYRSPL
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: MYL6_BOVIN
Sequence: MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG
What is the function of this protein?
Regulatory light chain of myosin.  Does not bind calcium.
What are the official names of this protein?
Myosin light polypeptide 6, 17 kDa myosin light chain, LC17, Myosin light chain 3, MLC-3, Myosin light chain alkali 3, Myosin light chain A3.
Protein: RL1_COREF
Sequence: MSKNSKAYREAAAKIDAGREYTPLQAAELVKETSSKNFDASVDVAIRLGVDPRKADQLVRGTVSLPNGTGKTVRVAVFAAGEKATEAEAAGADFVGTDELVERIQGGWTDFDVAIATPDQMAKIGRIARVLGPRGLMPNPKTGTVTNDVAKAIEEVKGGKISFRVDKASNLHAAIGKASFDAKALAENYGALIDELLRIKPSSSKGIYLKKITMSSTTGPGVAVDTHITKNYTAEA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: Y822_STAA3
Sequence: MAKKAPDVGDYKYGFHDDDVSIFRSERGLTENIVREISNMKNEPEWMLDFRLKSLKLFYKMPMPQWGGDLSELNFDDITYYVKPSEQAERSWDEVPEEIKRTFDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEEKGIIFKDTDSALQENEELFKKYFASVVPAADNKFAALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLIIADEGASVHYVEGCTAPVYTTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRTFVYENGNMEWVDGNLGSKLTMKYPNCVLLGEGAKGSTLSIAFAGKGQVQDAGAKMIHKAPNTSSTIVSKSISKNGGKVIYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYNEVFNDQISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
What are the official names of this protein?
UPF0051 protein SAUSA300_0822.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: DNAJ1_SYNY3
Sequence: MPGDYYQTLGVTRDADKDEIKRAYRRLARKYHPDVNKEPGAEEKFKEINRAYEVLSEPEIRQRYDQFGEAGVSGGGAQGFDVGNMGDFADIFETIFGGFGGGMGGQQRGRRRANGPTRGDDLRLDLQLTFQEAIFGGEKEIRIPHLESCQVCEGTGAKPGTGVKTCGTCNGAGQVRRATRTPFGSFAQVSACPTCNGSGEVIEQKCEACNGVGRKQETKKLKITIPAGVDDGTRLRVGKEGDAGLRGGPAGDLYVFLMVETDKHFVREGMNIRSNLEVSYLQAILGCRLEVDTVDGKAELTIPAGTQPNTVLTLENKGVPKLGNATIRGDHLITVKVQIPTRINSEERELLERLATIKGESHGKGGLEGFLGGLFHK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ 1.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_SYNP2
Sequence: MSAYLLTAPAKINLYLEILGDRPDGFHELVMVMQTIGLYDRIEVRQNRSGDINLYCQHPEVPLTASNIAYRAAQLMMTRFADIYARVGGGVDITIEKNIPVAAGLAGGSTDGAAVLVGLNLLWDLGLTQPELQTLAAELGSDVPFCIGGGTVIATGRGEILDPLPDLDGIPIVLAKYSNIAVSTPWAYQTYRAQFGEHYLQDAASWRTRMTQIHAGGLIKAIQQKNIQAIAHELHNDLEKVVLPEFPQVQQLRDCFTKHGAIGTMMSGSGPSVFALCETLAQAQALKVQVAQELNDPALDLWVTHIASPGIQADFR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: NIFA_BRADU
Sequence: MLHIPSSSERPASQPEPERAPPGEPSHESALAGIYEISKILNAPGRLEVTLANVLGLLQSFVQMRHGLVSLFNDDGVPELTVGAGWSEGTDERYRTCVPQKAIHEIVATGRSLMVENVAAETAFSAADREVLGASDSIPVAFIGVPIRVDSTVVGTLTIDRIPEGSSSLLEYDARLLAMVANVIGQTIKLHRLFAGDREQSLVDKDRLEKQTVDRGPPARERKQLQAHGIIGDSPALSALLEKIVVVARSNSTVLLRGESGTGKELVAKAIHESSVRAKRPFVKLNCAALPETVLESELFGHEKGAFTGAVSARKGRFELADKGTLFLDEIGEISPPFQAKLLRVLQEQEFERVGSNHTIKVDVRVIAATNRNLEEAVARSEFRADLYYRISVVPLLLPPLRERRSDIPLLAREFLRKFNSENGRSLTLEASAIDVLMSCKFPGNVRELENCIERTATLSAGTSIVRSDFACSQGQCLSTTLWKSTSYGKTDPAAPMQPVPAKSIIPLAETAPPPQAVCEPGSLAPSGTVLVSGARMADRERVVAAMEKSGWVQAKAARLLGLTPRQVGYALRKYGIEIKRF
What is the function of this protein?
Required for activation of most nif operons, which are directly involved in nitrogen fixation.
What are the official names of this protein?
Nif-specific regulatory protein.
Protein: SPEH_SYMTH
Sequence: MAYSTYGRHITMDLREVAFEKLNDVRFLKEVMYEAAAQCGATVVGESFVQFSPQGVTGVLVLSESHLSIHTYPEEGFAAIDCYTCGYTVDPAVACDYLKAALGGRVVGYRALRRGSGAIEDLTTLHLAAANN
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: IHFB_BRASB
Sequence: MIKSELVQRIAEHNPHLYQRDVENIVNAILDEIVAALARGDRVELRGFGAFSVKHRPARAGRNPRTGAHVPVDQKSVPFFKTGKEMRERLNRDNPAGAADTDD
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: RNY_CHLAA
Sequence: MTELLWAVVALLAGLAGGAGIGVYWANNGVSSLVQRKAAEARLLIEEARSQQKEILLQAKDEALRIRNEAEAELRESRQSLQKQEERLQRKEENIDRKLEGIERRERLIQQRERQIEQLTQEAERLKRQQAQELERISQLSREEARSIILAEVERETREDAARRIRELEQQTKEEADKIARKIIGLAIQRCASDYVAEMTVSTVNLPSEELKGRIIGREGRNIRAFEQITGVDIIVDDTPEAVTLSCHDPVRREVARVALLKLLKDGRIHPSRIEEVVHKTQLEIEQIMREEGERVAYEANVQGLHPDLIKLLGRLKYRTSYGQNVLQHSLECALLAAHMAAELGANVNIAKTAALLHDIGKAVDHEVQGPHALIGAEIARRLGRSAAIVHAIAAHHYDEEPQTVEAFLVIAADAISGARPGARRETLDLYIKRLEALETVATSFPGVQRAFAVQAGREVRVMVQPDQIDDLASIHLARNVAKKIEESLQYPGQIKVTIIRETRAVDYAR
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: Y1169_HAEIN
Sequence: MYPLFETLCIENGKIQNINLHQVRYERSLREYYGKSAVKIFNLFSLIQLPTPLQNQLIRCRIDYNAETTQIQYFEYQRKIYRTFQPVICDDIEYSLKYSDRSLINTLFAQRGACDEIMIIKNGKVTDCSIGNLIFRQGKKWYTPDTPLLLGTQREKLLQEGKIQERTIFQEDIVNFDEIKIINAMNGL
What are the official names of this protein?
Uncharacterized protein HI_1169.
Protein: PYNE_ASPNC
Sequence: MSKPTIAFLGATGGCINACLAHTLQTGYHAVALARTPSKLTALLRTQNIDQETLDSRLRIVTGDATDPEAVKSTLLLQPGFPTDPTTSASSPTPTLVSHIISGIGATGNFRGWCFEFDQPHICEEATRALLTALRNIYATYPEFMLPANVKSRPLLTVLSGMGVDPSQKQMDVPFLLRRVYHGLLHVPHADKWVMEEMLAKREAREFFRGVITVRPGSLLTGDHMLGSGYGYEKVRVGTEREEPSVGWTIPRADVGEWVFREVVVMGGGRWVDEKVTLTCW
What is the function of this protein?
Oxidase; part of the gene cluster that mediates the biosynthesis of pyranonigrins, a family of antioxidative compounds (PubMed:24106156, PubMed:26414728).  The first step of pyranonigrins biosynthesis is performed by the hybrid PKS-NRPS synthetase that condenses 6 malonyl-CoA units to an acetyl starter unit, to form a 1,3,5-trioxotetradecane-6,8-dienyl-ACP (PubMed:24106156).  The enoyl reducrase (ER) domain of pynA is likely to be functional during the first two rounds of polyketide chain extension, to generate the saturated C-C bonds of the alkyl side chain (Probable).  PynA subsequently forms the amide bond between the acyl chain and L-serine (PubMed:24106156, PubMed:26414728).  Although pynA has a terminal reductase domain, it appears to require the thioesterase pynI for the release of the straight-chain intermediate from pynA via the formation of a tetramic acid pyranonigrin J (PubMed:26414728).  The methyltransferase pynC then coverts pyranonigrin J to pyranonigrin I via N-methylation (PubMed:26414728).  The FAD-dependent monooxygenase pynG catalyzes an epoxidation-mediated cyclization to form the dihydro-gamma-pyrone moiety, followed by pynD-catalyzed oxidation of the alcohol to the ketone and enolization to yield the characteristic tetramic acid-fused gamma-pyrone core of pyranonigrin H (PubMed:26414728).  Pyranonigrin H is substrate of pynH for dehydration-mediated exo-methylene formation from the serine side chain to produce pyranonigrin E, before the oxidase pynE reduces the exo-methylene of pyranonigrin E into a pendant methyl to form pyranonigrin G (PubMed:26414728).  The FAD-linked oxidoreductase pynB performs the reverse reaction and converts pyranonigrin G back to pyranonigrin E (PubMed:26414728).
What are the official names of this protein?
Oxidase pynE, Pyranonigrin biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the avfA family.
Protein: UPP_SULIA
Sequence: MPLYVIDKPLTLHILTQLRDKNTDQINFRKNLVRLGRILGYEIANTLDYEIVEVETPLGARTKGIDITDLNNIVIINILRAAVPLVEGLLKAFPKARQGVIGASRVEVDGKEVPKDMDVYIYYKKIPNIRAKVDNVIIADPMIATASTMLKVLEEVVRANPKRIYIVSIISSEYGANKILSKYPFIYLFTVTIDPELNNKGYILPGLGDAGDRAFG
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: IF_RAT
Sequence: MAWLSFYLLNVLWAVAGTSTRAQRSCSVPPDQQPWVNGLQLLMENSVTESDLPNPSILIAMNLASTYNLEAQKLLTYQLMASDSADLTNGQLALTIMALTSSCRDPGSKVSILQKNMESWTPSNLGAESSSFYGPALAILALCQKNSEATLPIAVRFAKTLMMESSPFSVDTGAVATLALTCMYNRIPVGSQENYRDLFGQALKVIVDNISLRIKADGIIGDIYSTGLAMQALSVTPEQPTKEWDCEKTMYTILKEIKQGKFQNPMSIAQILPSLKGKTYLDVPQVTCGPDHEVPPTLTDYPTPVPTSISNITVIYTINNQLRGVDLLFNVTIEVSVKSGSVLLAVLEEAQRRNHMFKFETTMTSWGLIVSSINNIAENVKHKTYWEFLSGKTPLGEGVAYYIPFNYEHITANFTQY
What is the function of this protein?
Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum.  After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity).
What are the official names of this protein?
Cobalamin binding intrinsic factor, Gastric intrinsic factor, Intrinsic factor, IF, INF.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic cobalamin transport proteins family.
What are the subcellular locations of this protein?
Secreted.
Protein: PLSY_PSEPG
Sequence: MFWLLALLAYLLGSLSFAIVLSRLSGSPDPRSSGSGNAGATNMLRLAGRKLAILTLLGDLCKGLLPVLLARAAGLDLHAQAWVGVCAVLGHLFPLYFRFQGGKGVATAAGMLMGLYFPAALLAIGAWLLTFYLTRTSSLAALIATPLTLPLLAWREPEALLPITVLTAMIVWRHRKNLRDLFAGRERHF
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PAND_THEP1
Sequence: MLNIYLKSKIHMAKITRKEVYYEGSIEVDEELMEKAGISEGEVVLVVNVNNAARFVTYVIKGKRGSREINLYGAAARLGEEGDRVIIMAFTFSDKPVKAKTIVLNEKNEIIQEK
What is the function of this protein?
Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
What are the official names of this protein?
Aspartate 1-decarboxylase, Aspartate alpha-decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the PanD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_AYWBP
Sequence: MKFNNKKNTFKKRRKVCFFTENKVTKIDFKDIELLQRFITDRGRILSRRVTNTSARWQRQLAIAIKRARHMALIPFIQQ
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ILVD_SYNAS
Sequence: MRSDIMKKGLEKAPHRSLFKAMGYTDEEIARPLIGVVNAANEIIPGHIHLDRIVEDVKAGIRMAGGTPVEFPAIGICDGIAMGHLGMKYSLASRELIADSTEAMVMAHPFDGLVLVPNCDKIIPGMLMAALRLNIPSIFVSGGPMLAGRLDGKSVDLISVFEGVGAVKAGKMTEEQLKALEDCACPGCGSCSGMYTANSMNCVTEALGLGLPGNGTIPAIHAARRRLAKEAGVRIMDLVSKNIRPRDIATLDAFKNALAVDMALGCSTNTVLHIPAIAHEAGIRLDLDLFNEISARTPNLCHLSPAGPHHIEELDAAGGIQAVMKVISKLGVIQESALTVSGRTVGENLEKARVLNEEVIRPLDRAYRQEGGIAILRGNLAPDGAVVKQSGVLPEMMINEGTARVFDSEDEAIAAILGGKIVAGDIVVIRYEGPKGGPGMREMLSPTSAIAGMGLDTSVALLTDGRFSGGTRGAAIGHISPEAAEGGPIALIREGDWIAINIPEKTLTLKVDPEELEKRKQEWKPKASQNLTGYLARYARLVTSASTGAIFKD
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: PYRB_ALIF1
Sequence: MTNSLYQKHIISIPELSRQELELIVETAGKIKKEPQPDLLKNKIVASCFFEASTRTRLSFETAIQRLGGSVIGFDTAGNTSLAQKGETLADSVQIITSYADAYVMRHPQEGAARLASEFSNGTPVINAGDGANQHPTQTLLDLYTIYETQGRLDNLNVAFVGDLKYGRTVHSLTQALAKFEGIKFFFIAPEVLAMPDYICEELDELGIEYQLVESMDDAIPELDILYMTRVQKERFDESEYAHIKSAYILSAENLQPARENLKVLHPLPRVDEIDTDVDATPHAYYFQQAENGVYARQALLALVLNETL
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: SP2AB_CLOB8
Sequence: MSDNKMSIEFVSKSENEAFARVAVAAFVAQLDPTIDEINDVKTAVSEAVTNSIIHGYENREDGLVRIEAEINEDQVTIAIIDKGIGIDNIEQAMEPLYTSRPDLERSGMGFTVMETFMDALEVDSEKGNGTKVVIKKKFNVVS
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.
Protein: LDH2_LACLC
Sequence: MKITSRKVVVIGTGFVGTSIAYSMINQGLVNELVLIDVNQDKAEGEALDLLDGISWAQENVIVRAGNYKDCENADIVVITAGVNQKPGQSRLDLVNTNAKIMRSIVTQVMDSGFDGIFVIASNPVDILTYVAWETSGLDQSRIVGTGTTLDTTRFRKELATKLEIDPRSVHGYIIGEHGDSEVAVWSHTTIGGKPILEFIVKNKKIGLEDLSNLSNKVKNAAYEIIDKKQATYYGIGMSTARIVKAILNNEQVILPVSAYLRGEYGQEGVFTGVPSVVNQNGVREIIELNIDAYEMKQFEKSVSQLKEVIESIK
What is the function of this protein?
Catalyzes the conversion of lactate to pyruvate.
What are the official names of this protein?
L-lactate dehydrogenase 2, L-LDH 2.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: APOA2_NEOSC
Sequence: MKLLALAVLLLAVCSLEGAFVRRQAEEPNLQSLVAQYFQTMTDYGKDLVEKAKGPELQAQAKAYFEKTQEQLTPLVKKAGTDLINFLSNFMDLRTQPATQ
What is the function of this protein?
May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.
What are the official names of this protein?
Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2.
What is the protein family that this protein belongs to?
Belongs to the apolipoprotein A2 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HTPG_BURCH
Sequence: MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDPNLRIRIGYDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGDFTIDAIERAQRGTTITLHLREGEDDLLSSHRLKSIIQKYSDHIALPILMRKEEWDQEKGEMVLKDEDETVNQASALWTRSKSDVTDEQYTQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWGAFGQVLKEGLGEDHANRERIAKLLRFASTHGDTDAQDVSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHEFDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLTDSPSCLVADDNDMSGYLQRMLKAAGQNAPAMQPILEINPEHALVKQLNADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y373_CHLFF
Sequence: MEKIPYAILEKGSLLLASPDTDQGVFARSVILLCEHSLNGSFGLILNKTLGLELADDIFSFDKVTNNNIRFCMGGPLQANQMMLLHSCSEIPEQTLEICPSVYLGGDLSFLQEIAASDAGPMINLCFGYSGWQAGQLEREFLDGNWFLAPASYDYVFMDNPENLWSKILKDLGGKYASLSTVPENLFLN
What are the official names of this protein?
UPF0301 protein CF0373.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: NDK_WIGBR
Sequence: MKIEQTLSIIKPNIISNNFIGNIINRLEQAKLYIIASKMIKLSWKEAVSFYIEHKNKSFFSDLINFMISHPIIVQILEGENAIKRNREIMGNTNPKIALAGTLRSDFSNDIIKNGVHGSDSEESADREIKFFFKKDRIFSRI
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y047_CHLPN
Sequence: MTIVGFFRFVLEGILTMYHFQKIRMTLTTQGFVLNKSLRKDYELWFVYGSCPESKVKLQTSSHKWL
What are the official names of this protein?
Uncharacterized protein CPn_0047/CP_0727/CPj0047/CpB0048.