PharMolix/UniProtQA huggingface dataset:
Protein: MLTF_PHOPR
Sequence: MLSNNPLITKFRELFTVALVLALLSGCQWQDDNLTDLEKIRESGVIRVGTLNNQLSYYIGNDGPTGLDYELAQRFAQKLGVKLEMQPMFTLSGLFPTLERGGIDVVAAGLTISKDRIENYHAAPAYYYASQIVVYKNGQWRPRKPADLALNKGTLSVVKGSSHEKHLIKLKEIHPDLTWESIEETDSDELLRLVAKGELDFTIADSVDVALSQRIHPDVAIAMELTEDEPIAWFVNKSTDDSLYALLIEFFGEIKQSGELAQLEEKYFGHVGSFDYVDTRAFLRAIESKLPRWESLFKKYSNEFDWRLIAALSYQESHWNPQAVSPTGVRGMMMLTLPTAKSVGVKNRLDPEQSIRGGAEYLRKMISRVPDSIESHEKVWFALASYNVGFGHMMDARRLTHKQGGNQDTWTDVKQRLPLLRQRKYYQQSRYGYARGDEALNYVENIRRYYQSIIGYEQAHSHDYDSDDVQVVDGLQTITLPPVPPRQANVDGSLNNEAAISSAEKTIEDPGPSQ
What is the function of this protein?
Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product.  Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus.  Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
What are the official names of this protein?
Membrane-bound lytic murein transglycosylase F, Murein lyase F.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transglycosylase Slt family.
What are the subcellular locations of this protein?
Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane.
Protein: MAP1_TREPA
Sequence: MIRIKTPEQIDGIRASCKALARLFDVLIPLVKPGVQTQELDAFCQRFIRSVGGVPAWFSEGFPAAACISINEEVIHGLPSARVIQDGDLVSLDVGINLNGYISDACRTVPVGGVAHERLELLRVTTECLRAGIKACRAGARVRAVSRAVYAVAARHRFGVVYEYCGHGVGLAVHEEPNIPNVPGLEGPNPRFLPGMVVAIEPMLTLGTDEVRTSADGWTVVTADGSCACHVEHTVAVFADHTEVLTEPTEVERTG
What is the function of this protein?
Removes the N-terminal methionine from nascent proteins.  The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).  Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
What are the official names of this protein?
Methionine aminopeptidase, MAP, MetAP, Peptidase M.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
Protein: CLOA_CLAFS
Sequence: MLLLWLYQALPTSLTRILLTAGLCVPCALVIHGIYNLYFHPLRNVPGPKLGALTDLYAFYWNWIRGVGYSKQFDRWHKHYNSSVIRIGPNDVHTTQVELYDVIHKAGSTWLKDKSFYKHFGGLDAMIDPREYRTYRTHLAPLYSQRAVDGLVSKMDDDLAICGQKTTKMAENGKAVNMARVLTTLSTSMILYNLFSMDISLWECNDYHPFLEAFEHIMAQIWLFLSYPRLATCLSLIPGTSLARLAPSWTTFMNSCAAWCDEDARKQRASDDQSIRDSHSKRYYALKHTDANDKKSIIPAPLDELFSFIAGGTDTTAYTTGCAFFYILSSPSVCRKLVKELDENASFIRNGLDYHKIQTLPYLNAVIKETLRISVPVPGCLPRVVPEGGITVGSFHLPAGTALSITQQAISLNQDIFPSPLCFSPERWIGPAAAGLDKWNVAFGRGSRQCIGTTLAYLELRCVVAYFFSRFDMTLTAKNGDGHRWVDRFVAVNLDTVEVLVLSDRWSGARY
What is the function of this protein?
Inactive cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fungal ergot alkaloid (PubMed:17720822).  DmaW catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan (By similarity).  The second step is catalyzed by the methyltransferase easF that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of 4-dimethylallyl-L-abrine (By similarity).  The catalase easC and the FAD-dependent oxidoreductase easE then transform 4-dimethylallyl-L-abrine to chanoclavine-I which is further oxidized by easD in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde (By similarity).  Agroclavine dehydrogenase easG then mediates the conversion of chanoclavine-I aldehyde to agroclavine via a non-enzymatic adduct reaction: the substrate is an iminium intermediate that is formed spontaneously from chanoclavine-I aldehyde in the presence of glutathione (By similarity).  Further conversion of agroclavine to paspalic acid is a two-step process involving oxidation of agroclavine to elymoclavine and of elymoclavine to paspalic acid, the second step being performed by the elymoclavine oxidase cloA (PubMed:17720822).  However, cloA does not encode a functional enzyme indicating that C. fusiformis terminates its ergot alkaloid pathway at elymoclavine (PubMed:17720822).
What are the official names of this protein?
Inactive cytochrome P450 monooxygenase cloA, Ergot alkaloid synthesis protein cloA, Inactive clavine oxidase, CLOA.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSBN_EUGGR
Sequence: FKIISFLSTIFLGFFIISTTIYSIYMGFGPMSRKLKDPFEEHEN
What is the function of this protein?
May play a role in photosystem I and II biogenesis.
What are the official names of this protein?
Putative protein PsbN.
What is the protein family that this protein belongs to?
Belongs to the PsbN family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: NSS_BUNL8
Sequence: MMSHQQVQMDLILMQGIWTSVLKMQNYSTLLQLGSSSSMPQRPRLLSRVSQRGRLTLNLESGRWRLSIIIFLETGTTQLVTTILPSTDYLGI
What is the function of this protein?
Inhibits host transcriptional machinery, by producing modifications to the phosphorylation state of the C-terminal domain (CTD) of RNA polymerase II.  Inhibits phosphorylation at serine 2 in the heptapeptide repeat (YSPTSPS) of the CTD of RNA polymerase II, suggesting that the elongation step of transcription and/or 3'-end processing is prevented.  Inhibition of host transcription machinery leads to shut off of host cell protein synthesis and inhibition of the host innate immune response.  NSs also seems to be involved in the nuclear relocalization of host PABP1 (By similarity).
What are the official names of this protein?
Non-structural protein NS-S.
What is the protein family that this protein belongs to?
Belongs to the orthobunyaviruses NS-S protein family.
Protein: YNCI_ECOLI
Sequence: MSIQSLLDYISVTPDIRQQGKVKHKLSAILFLTVCAVIAGADEWQEIEDFGHERLEWLKKYGDFDNGIPVDDTIARVVSNIDSLAFEKMFIEWMQECHEITDGEIIAIDGKTIRGSFDKGKRKGAIHMVSAFSNENGVVLGQVKTEAKSNEITAIPELLNLLYLKKNLITIDAMGCQKDIASKIKDKKADYLLAVKGNQGKLHHAFEEKFPVNVFSNYKGDSFSTQEISHGRKETRLHIVSNVTPELL
What are the official names of this protein?
Putative transposase YncI.
What is the protein family that this protein belongs to?
Belongs to the transposase 11 family.
Protein: ABDA_AEDAE
Sequence: MSNPFDRVVCGDFAGPNGCPRRRGRQTYTRFQTLELEKEFHFNHYLTRRRRIEIAHALCLTERQIKIWFQNRRMKLKKELRAVKEINEQARREREEQDKMKNDSLKSAQQHHNSQKQQEQTIVGSQQSSGGGGGGGGGGGSSSLGSHLHHPSIVAQNDLKLGLGSMGVGVGVGGNLSMMGGLDNKTNQDILKARGSLVRESFFTVNETILRLRWTTREYVIVALFYPVAASSLLLKFRD
What is the function of this protein?
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
What are the official names of this protein?
Homeobox protein abdominal-A homolog.
What is the protein family that this protein belongs to?
Belongs to the Antp homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PDXH_NEIMA
Sequence: MDLHNIREDYSKRELSEGDCADNPIEQFERWLDEAVRAQVNEPTAVNVAAVDGRGRPNSRMVLLKEVNSEGFVFFTNYHSRKGRSLDAHPFAAMTFFWPELERQVRVEGRVERLAEKLSDEYFESRPYQSRLGAWASAQSEVIPNKAVLVAKAAAVGLKHPLHVPRPPHWGGYIVIPDLIEFWQGRPSRLHDRIQYRLLDGGWIRERLSP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: KHSE_ZYMMO
Sequence: MAVYTSVSDEEVSSFLDLYPDSGRLLSIKGITEGVENSNYLITTDVRSYILTLYEKRVNPEELPFFMALTDHLAAENLPVPKAWKSRDGKQIQTLAGRPACLIEFLQGRWTPTPNAEQTRATGEMLGKMHKSLTHFSENRKNSLDLENWHILAEKCGFEAMNQIEAHMGDEVKKELDYLDKFWPKDLPRSVIHADLFPDNVLFEGDSLKGVIDFYFACTEVRAWDLAITYSAWCFDQEDHFLADHAKALIKGYHQSFALTEEERAAFIVLLRGAALRFLLTRAWDWVNTPPDALVVPKDPRDFFKRLRFYREASLESLGF
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the pseudomonas-type ThrB family.
Protein: HEMH_CHLPN
Sequence: MTTPAYLLANFGGPRHAKDLQEFLISLLTDRDVTGTFLPRVLHRHLFTFIAKKRVPKVLPQYQSLQNWSPIYFDTETLAKTLSEILRAPVIPFHRYLPSTHEKTLLALRTLHTRHVIGIPLFPHFTYSVTGSIVRFFMKHVPEIPISWIPQFGSDSKFVSLITCHIRDFLQKLGILEKECCFLFSVHGLPVRYISQGDPYSKQCYESFSAITTNFKQSENFLCFQSKFGPGKWLSPSTAQLCQNIDTDKPNVIVVPFGFISDHLETLYEIERDYLPLLRSRGYRALRIPAIYSSPLWVSTLVDIVKENSTVVAEELIKSGKKHTGIR
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN620_HUMAN
Sequence: MFQTAWRQEPVTFEDVAVYFTQNEWASLDSVQRALYREVMLENYANVASLAFPFTTPVLVSQLEQGELPWGLDPWEPMGREALRGICPGDEARTEKEGLTPKDHVSKETESFRLMVGGLPGNVSQHLDFGSSLEQPQGHWIIKTKSKRRHFTDTSARHHEAYEVKNGEKFEKLGKNISVSTQLTTNQTNPSGQISYECGQCGRYFIQMADFHRHEKCHTGEKSFECKECGKYFRYNSLLIRHQIIHTGKKPFKCKECGKGLSSDTALIQHQRIHTGEKPYECKECGKAFSSSSVFLQHQRFHTGEKLYECNECWKTFSCSSSFTVHQRMHTGEKPYECKECGKRLSSNTALTQHQRIHTGEKPFECKECGKAFNQKITLIQHQRVHTGEKPYECKVCGKTFSWCGRFILHQKLHTQKTPVQA
What is the function of this protein?
May be involved in transcriptional regulation.
What are the official names of this protein?
Zinc finger protein 620.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: NUOK_PSEPF
Sequence: MPAIPLEHGLAVAGILFCLGLVGLMVRRNILFVLMSLEVMMNASALAFIVAGARWAQPDGQIMFILVISLAAAEASIGLAILLQLYRRFHTLDIDAASEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPLB_CLOAB
Sequence: MENMFRRVIFEKKALDYPMGRDILRQFENTDIEIRYSETGRITGIPGKDEAQSFFEGKNTLVVGVRRELDFQTCKPSANYQLPIVSGCAAMCEYCYLNTHGGKKPYVKINVNLDDILSKAGEYIEKRKPDITVFEGAAISDPVPVERYSGALKKAIEYFGKNEYSRFRFVTKYADISELLAVQHNNHTTIRFSINTPRVIKNYEHRTSSLEDRIESAYNILNSGYKTGFIVGPVFLYENWKKEYEELLKKASDKLGDKELEFEIISHRFTTSAKNKILKVFPNTKLPMDDEARKFKFGQFGYGKYVYDKDDMQEIKEFFINNINLYFNKATIKYII
What is the function of this protein?
Involved in repair of UV radiation-induced DNA damage during spore germination.  Can repair thymine dimer 5-thyminyl-5,6-dihydrothymine (known as spore photoproduct (SP)) by in situ monomerization of SP to two thymines.
What are the official names of this protein?
Spore photoproduct lyase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. SPL family.
Protein: FADA_ACIBC
Sequence: MATLNPRDVVIVDGVRSAMGKSKNGMFRNVRADSLSAELVRALVARNQFDVNEVEDLIWGCVNQTLEQGMNIGRNIGLLAGLPKTVAGQTVNRLCGSSMQAIHTAAAQIATNQGDIFIIGGVEHMGHVGMMHGIDLNPEASKHYAKASNMMGLTAEMLGRMNGITREEQDAFGVESHRRAWAATQEGRFKNEIIGVEGHDANGFKILCDIDEVIRPDANLEAFKALKPVFDPKGGSVTAATSSALSDGASAMLLMSAERAQALGLKPRAVIRSMAVAGCDAAIMGYGPVPATQKALKRAGLSIADIQTVELNEAFAAQGLSVLKGLGLYDKQDIVNLNGGAIALGHPLGCSGARITTTLLNVMEQQDTQIGLATMCIGLGQGIATVIERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMAA_MOUSE
Sequence: MTISTLLLSPNRRLLTCLSRVPSPWLLHSSHPAPGPPGALPNCFGHHCTKRVLLSDGFRRTLCVQATLKDHTEGLSDKEQRFVDRLYTGLVKGQRACLAEAITLVESTHTRKRELAQVLLQRVLALQREQELRNQGKPLTFRVGLSGPPGAGKSTFIECFGKMLTEQGHRLSVLAVDPSSCTSGGSLLGDKTRMIELSRDMNAYIRPSPTSGTLGGVTRTTNEAIVLCEGGGYDIILIETVGVGQSEFAVADMVDMFVLLLPPAGGDELQGIKRGIIEMADLVVITKSDGDLIVPARRIQAEYVSALKLLRRRSEVWRPKVIRISARSGEGITEMWDTMREFQHQMLASGELAAKRQTQHKVWMWNLIQENVLEHFKTHPSIREQIPLMERKVLSGALSPGRAADLLLKAFKSRH
What is the function of this protein?
GTPase, binds and hydrolyzes GTP (By similarity).  Involved in intracellular vitamin B12 metabolism, mediates the transport of cobalamin (Cbl) into mitochondria for the final steps of adenosylcobalamin (AdoCbl) synthesis (By similarity).  Functions as a G-protein chaperone that assists AdoCbl cofactor delivery from MMAB to the methylmalonyl-CoA mutase (MMUT) (By similarity).  Plays a dual role as both a protectase and a reactivase for MMUT (By similarity).  Protects MMUT from progressive inactivation by oxidation by decreasing the rate of the formation of the oxidized inactive cofactor hydroxocobalamin (OH2Cbl) (By similarity).  Additionally acts a reactivase by promoting the replacement of OH2Cbl by the active cofactor AdoCbl, restoring the activity of MMUT in the presence and hydrolysis of GTP (By similarity).
What are the official names of this protein?
Methylmalonic aciduria type A homolog, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: ATPG_EHRCR
Sequence: MANLKALLLRIKSVKSIQKTTKVMQMISAAKLHRVQQKLENAKKHLLELSSIVDYVPSDGVHNCASIAKKERVLLVVMSSDRGLCGNFNNLIVKFTKSYVEKLESSNKEVKLIFFGKKAYDMMYSQYSDKILNVFSNTKSITDFLYFKLFVYNSGIDFDQFDNVMILFNKFYTTILQKPDAQQLIPCNLGIPMLLKEVYQYEPTYVDVLSTISLGYVLNLMYIAFLENSASEHCSRMVAMESANRNTKDMLNRLALEYNRSRQASITTDLIEIISGFESLN
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HSLO_HAES1
Sequence: MIYQTDNDKLYRYLFKDRAVRGEWVRLNKTFTDTLNSHEYPRIVRNLLGEMMVATNLLTATLKFKGNITIQIQGNGPLKLLLVNGSDSQQIRALARLQDDVYDDMTLSELVGNGILVITIAPTNGERYQGVIALDKPTIAECLEDYFIRSEQLQTQLLIRSGEYEGKPVAAGLLLQIMPDGTGSQEDFEHLATLAATVKDEELFGLTAENLLYRLYHEETVEIYPPSAVEFHCGCSLERSGSALLLISDDEIENILTEHGGSIDMQCECCGTHYFFDKKTIEKLKA
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H16E1_CYRHA
Sequence: MNTVRVTFLLVFVLAVSLGQADKDENRMEMLEKTEQGKSYLDFAENLLLQKLEELEARLLEEDSEESRNSRQKRCIGEGVPRDENDPRCCSGLVCLKPTLHGIWYKSYYCYKK
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U11-theraphotoxin-Hhn1e, U11-TRTX-Hhn1e, Hainantoxin-XVI-5, HNTX-XVI-5.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 14 (magi-1) family. 01 (HNTX-16) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: WH16_STRCO
Sequence: MTDQQVRIVSLGDIAPNRRRGGDLRALLTPTTAGSTSGFMGVAIVQPGDRIAEHYHPYSEEFVYVTEGALEVDLDGVPHSLGTGQGLLIPQDMRHRFRNAGDVEARLVFHLGPLAPRPELGHVDTEDAEGNALPCDGAHAGHAAGHERPAPAAEVVS
What are the official names of this protein?
16.7 kDa protein in whiE locus, WhiE ORF II.
What is the protein family that this protein belongs to?
Belongs to the SchB/CurC family.
Protein: SRC30_ARATH
Sequence: MRRYSPPYYSPPRRGYGGRGRSPPPPPPRRGYGGGGGGGGRRGSSHGSLLVRNIPLDCRPEELREPFERFGPVRDVYIPRDYYSGQPRGFAFVEFVDAYDAGEAQRSMNRRSFAGREITVVVASESRKRPEEMRVKTRTRSREPSGSRDRSHGRSRSRSISRSRSPRRPSDSRSRYRSRSYSPAPRRRGGPPRGEEDENYSRRSYSPGYEGAAAAAPDRDRNGDNEIREKPGYEAEDRRRGGRAVSRSPSGSRSRSVEVSPR
What is the function of this protein?
Involved in intron recognition and spliceosome assembly (Probable).  Probably active at the 5' splice sites.
What are the official names of this protein?
Serine/arginine-rich SC35-like splicing factor SCL30, At-SCL30, AtSCL30, SC35-like splicing factor 30, Serine/arginine-rich splicing factor 30.
What is the protein family that this protein belongs to?
Belongs to the splicing factor SR family. SCL subfamily.
What are the subcellular locations of this protein?
Nucleus speckle.
Protein: SNIP1_HUMAN
Sequence: MKAVKSERERGSRRRHRDGDVVLPAGVVVKQERLSPEVAPPAHRRPDHSGGSPSPPTSEPARSGHRGNRARGVSRSPPKKKNKASGRRSKSPRSKRNRSPHHSTVKVKQEREDHPRRGREDRQHREPSEQEHRRARNSDRDRHRGHSHQRRTSNERPGSGQGQGRDRDTQNLQAQEEEREFYNARRREHRQRNDVGGGGSESQELVPRPGGNNKEKEVPAKEKPSFELSGALLEDTNTFRGVVIKYSEPPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQYRLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYVLLHESSDTSEIDRKDDEDEEEEEEVSDS
What is the function of this protein?
Required for pre-mRNA splicing as component of the spliceosome (PubMed:29360106).  As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable).  Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding.  Involved in the microRNA (miRNA) biogenesis.  May be involved in cyclin-D1/CCND1 mRNA stability through the SNARP complex which associates with both the 3'end of the CCND1 gene and its mRNA.
What are the official names of this protein?
Smad nuclear-interacting protein 1, FHA domain-containing protein SNIP1.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFTU_LEPBA
Sequence: MAKEKFDRSKPHLNIGTIGHVDHGKTTLTAAITTTLAKLVGGKNKAIAYDQIDNAPEEKARGITIATSHQEYETPNRHYAHVDCPGHADYVKNMITGAAQMDAAILVVSATDGAMPQTKEHILLARQVGVPYIVVYLNKADMLAADERDDMVEMVKEEIKDLLNKYNFPGDKTPFISGSALKALEGEDSDLGMKSILKLMEAVDTYVPNPTRIVDKPFLMPVEDVFSITGRGTVATGRVEQGVLKINDEIEIVGIRDTTKSVVTGIEMFRKLLDQAEAGDNIGALLRGTKKEDIERGQVLAKPGTITPHRKFKAEVYVLTKDEGGRHTPFFNNYRPQFYFRTTDITGVCNLPGGMEMVMPGDNVTMSIELIHPIAMDQGLKFAIREGGRTIGSGVVAEIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_LIMRJ
Sequence: MEARDIILRPVVTEASMAGMDNKRYTFDVDLRATKTQVKNAVEEIFGVKVVKVNIMNVKGKLKRQGRYEGYTKRRRKAIVTLSADSNEIKLFNDNNEN
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: Y2524_BACCN
Sequence: MAMRFLNIGYGNIVSAHRIIAIVSPESAPIKRTVQEAREHNALLDATYGRKTRAVIVMDDGHVVLSPIQPETIAHRLNNKEDLSEEG
What are the official names of this protein?
Putative regulatory protein Bcer98_2524.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: FA2H_MOUSE
Sequence: MAPAPPPAASFTPAEVQRRLAAGACWVRRGASLYDLTSFVRHHPGGEQLLLARAGQDISADLDGPPHRHSDNARRWLEQYYVGELRADPQDPTENGAVASAETQKTDPALEPQFKVVDWDKDLVDWQKPLLWQVGHLGEKYDEWVHQPVARPIRLFHSDLIEAFSKTVWYSVPIIWVPLVLYLSWSYYRTLTQDNIRLFASLTREYSMMMPESVFIGLFVLGMLFWTFVEYVIHRFLFHMKPPSNSHYLIMLHFVMHGQHHKAPFDGSRLVFPPVPASLVIAFFYVFLRLILPETVGGIIFAGGLLGYVLYDMTHYYLHFGSPHKGSYLYNMKAHHVKHHFEYQKSGFGISTKLWDYFFHTLIPEEAHPKMQ
What is the function of this protein?
Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis (PubMed:15658937, PubMed:16998236, PubMed:22517924).  FA2H is stereospecific for the production of (R)-2-hydroxy fatty acids (PubMed:22517924).  Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath (PubMed:15658937, PubMed:18815260).  Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier (By similarity).  Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis (PubMed:21628453).  Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins (PubMed:22517924).
What are the official names of this protein?
Fatty acid 2-hydroxylase, Fatty acid alpha-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the sterol desaturase family. SCS7 subfamily.
Protein: Y3954_PSEA6
Sequence: MESKVIWSDVLRSWLPKANIFVRMFVNHCQRDGITVSAGHLAYVSLLSLVPFIMVFFTILSAFPAFSEVRGDIEALIFGNFIPTSGDQIQGYVAEFVGNASKMGAIGILSLVVVALLLISNIDKTLNRIWQAKSERPIIFTFAIYWMILTLGPLLIGLSVIMSSYLVAFANSAEAYTMGATTAMLKIVPFIASVCAFFILYMIVPNKRINPRHALVGAFMGALLFELSKKGFSFYITHFPSYQMIYGAMAVIPILFVWVYLSWIVVLLGAELTHVIEVFFHEESKENFTQVDEDDPQSPA
What are the official names of this protein?
UPF0761 membrane protein Patl_3954.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.