PharMolix/UniProtQA huggingface dataset:
Protein: H3V2_DICDI
Sequence: MTSVNNNMTSRRNLVLREIKRQILWAWTDPKSYRMSVGAIHALRTAFECYMNIIMTDCAIMAAHGKRKTITDRDIAFHQYIKPFYLPRY
What are the official names of this protein?
Histone H3.v2.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
Protein: ENO_FLAJ1
Sequence: MSIIIKVHARQILDSRGNPTIEVDVVTENGVLGRAAVPSGASTGEHEAVELRDGGKAYLGKGVLNAVNNVNTVIAEELVGTSVFEQNTIDQLMIDLDGTPNKSKLGANAILGVSLAAAKAAANELGLPLYRYVGGVSANTLPVPMMNIINGGSHSDAPIAFQEFMIFPVKATSFTHAMQMGTEIFHSLKKVLHDRGLSTAVGDEGGFAPNLAGGTEDALDTIKLAVEKAGYTFGDEIMIALDCAASEFYVDGKYDYTKFEGETGKIRTSAEQADYLAELAAKYPIISIEDGMYEDDWDGWKALTEKIGNKVQLVGDDLFVTNVARLSTGIEKGIANSILVKVNQIGTLTETIAAVNMAKNAGYTSVMSHRSGETEDNTIADLAVALNCGQIKTGSASRSDRMAKYNQLLRIEEELGSTAYFPGLNAFKIK
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: TRMA_SALA4
Sequence: MTPEHLPTEQYEAQLAEKVARLQSMMAPFSGLVPEVFRSPVSHYRMRAEFRLWHDGDDLYHIMFDQQTKSRIRVDTFPAASQLINTLMKAMIAGVRDNHALRHKLFQIDYLTTLSNQAVVSLLYHKKLDEEWREAATALRDALRAQGLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALEVTKDSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKRYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLETLSQTHTVSRLALFDQFPYTHHMECGVLLTAR
What is the function of this protein?
Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).
What are the official names of this protein?
tRNA/tmRNA (uracil-C(5))-methyltransferase, tRNA (uracil(54)-C(5))-methyltransferase, tRNA(m5U54)-methyltransferase, RUMT, tmRNA (uracil(341)-C(5))-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
Protein: SXM1_YEAST
Sequence: MVQEQAILSCIEQTMVADAKIIKEAEQQLFEFQKQPGFTSFLLNIVSDDNFALNVRLSSAIYLKNKIHRSWDTKREDGIKADEKLSIKERLIETLVKNCENNHIRPILTETINGILVGQEDWDLAPIIKNLLSSGDASYIYPGLLLLFQLCKAHRWDMVGSRDYIDSVIEELFPIVEGIASNIGSQTDYRSNEILYLILKSFKYACLNNLPQYFSQPERIMSWVQLHLYLCSKPLPVEVMELDPADRSLDKRVKVNKWGFGNLNRFLQRYNKITKAITKEFIDYIFNTIVPIILREFFKDIEAWGNNSLWLSDSSLYFLISFLEKCVTIDQLYPLIEPHLQIIFENVIFPCLCANEQSIELLEDDQEEYTRRYFDINREGSTPDAASADFIFLIGSKRPEKLNNILPFINDIFTRFDANSSDINMAFKEEGALRTLSNLFSFIDEPSVLENIFGHFIVPLLSQDKYMFLVARSLETIALYSEEFKDMNILSQLFELTYTNFLNSNVLPVQIEAADAIKCLIVSNPQIHPAVSAHVPGMMEKLLKLSKIFEIDILSEVMEALVERFSDELSPFAKDLASNLVEQFLRIAQALVENPSETYSASDQEQEIQASGLLQTMTTMVMSMNKVPLIESLAPVVKFVVLHAQISFITEAVDLLDALTISSHLLYNQIAPPIWELLHDILDSFQTYAMDYFEAYSIFFETIVMTGFPQDQTYVQPLLEILSAKLESEVDYDIEHVMQILMYFALSMRDIPLFSKAIKVSTNDELGLDSKCIVKLGLANLFAKPIETLQIMENEGFTINFFTNWFNEKFYSVFAIKLQVLVILTLLKMPEVPNSVSPLLNNLTNKLVELTLSLPKAIRNRDAVTEGKSLEGDLTPEEEEEYFIECDDDMKETVLDQINVFQEVHTFFKNLQNEDAGKYEKIINYLDESKRDSLQVILEFVSQH
What is the function of this protein?
Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm.  Required for the nuclear import of ribosomal proteins (RPL11, RPL16, RPL25, RPL31A), the poly(A)-binding protein PAB1, the HO endonuclease or the tRNA and snRNA chaperone LHP1.  Indirectly involved in nuclear mRNA export through its PAB1 nuclear import activity.
What are the official names of this protein?
Importin beta SMX1, Suppressor of mRNA export mutant protein 1, karyopherin-108.
What is the protein family that this protein belongs to?
Belongs to the importin beta family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nuclear pore complex.
Protein: UNG_PHOV8
Sequence: MNVQIEESWKQHLAPEFEKDYFIRLTEFVRSEYQTATIYPPGRFIFNAFNLCPFDKVKVVIIGQDPYHGPGQAHGLCFSVNDGVPFPPSLQNIFKEIQSDLGAPIPTSGNLTRWANQGVLLLNATLTVRAHQAGSHQRRGWEEFTDAAIRVLAEQRENIVFILWGSYAQKKGAFIDRNKHLVLASAHPSPLSAYNGFFGNKHFSRTNEYLQAHGQTPIEW
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_ECO7I
Sequence: MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAMAKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQQVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNICTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLADLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRSEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: TILS_PSEAE
Sequence: MPAVPLESRLLQALAPWREAGGWCVAFSGGLDSTVLLHLLAQLARSEALPALSALHVHHGLQAAADGWPAHCQAVCRSLGIPLRVERVQVAVGGSIEQAARDARYRAFQANLGEGQVLLTAQHLDDQAETLLFRLLRGAGLRGLAAMPASRPLGGGRLCRPLLGVSRAELEAYAQAHRLDWVEDPSNQDPRFSRNYLRREIMPRLASHWPQAVAGMARCAAHLREAEDLLAELAAIDLRACRQPSELDWPDWLDLPRIALEPLRRLSAARQRNLLRAWLGQLTRLPDSDHWAGWESLRDAGDDADPIWRLESGELRRGAGRIWWLPADWRAAAGPFVWERPAHPLLLPGNGRLALLGEVPAGPLRVDYRRGGEVLALAGRGRRDLKRLLNEAGVPSFLRGRLPLLFRADELLAVANIPGLDSPREGGWRLSWSPPTNDPGLS
What is the function of this protein?
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner.  Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
What are the official names of this protein?
tRNA(Ile)-lysidine synthase, tRNA(Ile)-2-lysyl-cytidine synthase, tRNA(Ile)-lysidine synthetase.
What is the protein family that this protein belongs to?
Belongs to the tRNA(Ile)-lysidine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGSA_RICPR
Sequence: MRIDKNLPNYLTIARIMVIPVIILLFYINNSLARKLGALLFVLASITDFFDGYIARKYNLVTSFGKMFDPIADKLLVGCVTIMLLKKDNVDEIPCLLILAREFLVSGLREFLALVKVSVPVSRLAKLKTFLQMFALSILILGSKGSGIIYLDIVGEIILWIAAFLTIITGYSYFKACKTYF
What is the function of this protein?
This protein catalyzes the committed step to the synthesis of the acidic phospholipids.
What are the official names of this protein?
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, Phosphatidylglycerophosphate synthase, PGP synthase.
What is the protein family that this protein belongs to?
Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_NEOYE
Sequence: MTLQISAQVVKALRDKTGAGMMDCKKALQANNGNEEKALESLRQKGLASANKKSNRTAIEGLLESYIHTGGRIGVLVEVNCETDFVARRPEFQKLAKDIAMQIAASPNVEYVSTQDIPSEIINLEQRVEAGKDDLKNKPVDRIETIIEGRMKKRLKELSLLDQMFIRNQDISIEDLINQNIAVLGENIKIRRFVRFLLGGGEENLKVNFADEVADILNKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, chloroplastic, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: RM15_CHICK
Sequence: MSGNGVHGVHGALQLLRSLPKVSLANLRPNPGSKKPERRRGRGRYRGRKCGRGHKGERQRGNRPRLGFEGGQTPFYLSIPKYGFNEGHSCRRKYHPLSLQKLQYLIDLGRVDPTQPIDLTQLTNARGVTVQPLKRDYGVQLVEEGADIFAAKINIEVQRASELAIAAIEKNGGVVTASFYDPRSLEILIRPVPFFLRGQPIPKRMLPPEDLVRYYTDASNRGYLADPSKVAEARLELAKKYGYTLPDITKDELFKMLSTRKDPRQIFFGLAPGWIVNMADKKILKPTDERLLKYYSS
What are the official names of this protein?
39S ribosomal protein L15, mitochondrial, L15mt, MRP-L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: Y951_ENT38
Sequence: MFGGKGGLGGLMKQAQQMQEKMQKAQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKDMLEDLVAAAFNDAARRIDETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Ent638_0951.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: C2D1_CAEEL
Sequence: MNFNDIDNQMYGNLEEDAELLAELAAIQEEEMGRVSRPAAPARGAPPAARGRPAPAAPANVPGLDPRLLAAALADNHGDGGDEELEMDEDLLNELNGLVGGGGGGGAAPTVPTRAAPRAPGPSGPPPSASAPNSQLGHLKQLHVYYMKAHKSAEQAGEGPKARRYKRAVDKLVELIRAVERGKTIDESEIPVAPPNFSSAAAEPLPPPAPTAQPAHHPPAPPIRQAAHAAESSPPPIPQRKSSAPAPTAAAPPATKEPTDPKKAAIYRILHHRRDLHKQNARAAIADKDKESAKESVEMAKAFDQAIAALNECSADEMDMNDVPPSPPPYRKPAPPQPQAPPTSAGPLGFIEELQQRQQRFQKMAEKAKTEGNERKMKMNMRLAGQFDEAIKEAKRGKLVNVGELPSLPDMGPLPPQTAPGQAAPKLHQRPPPQEVGPLAPSGVEGKSRNQGQLEFLLERQAQFKQAAIHAKSRGDVEAAKKYLVEMKGFDKMIQAAQAGLPVSIKATPIPPQAQTASTTLQPRIQSAAASSSTGVENRGEKLSLLEKTLIEQVRSAETNQMRFTRLGDVGKVRLFEGWGKVAKQDLLLVREVAKRGLQVPKFHYEMRQIPSADLFPDLADDVIELTIVSCRDVPLPSGYETHHANLFIKYTFPAVVNDLPQTGKTKLIAGTASPDFGESIMLNIGSGKSRNSKLQRTFKRGGLKFEVFQKGGFMRSDKLLGTCEWKLEKLEHSAEMEESLPLKDGRKAVGGLLSAKVRIRQPIGDAKAQHIAQKWLILDN
What are the official names of this protein?
Coiled-coil and C2 domain-containing protein 1-like.
What is the protein family that this protein belongs to?
Belongs to the CC2D1 family.
Protein: HIS81_BACCR
Sequence: MRVKEQLLTLRAYVPGKNIEEVKREYGLSKIVKLASNENPFGCSARVTEALTSLASQYALYPDGYAFELRTKIAEHLGVKAEQLLFGSGLDEVIQMISRALLHEGTNVVMANPTFSQYHHHAVIEGAEVREVSLKDGIHDLDAMLEQVDEKTKIVWICNPNNPTGTYVEKQKLLSFLESVPKSALVIMDEAYYEYAEAEDYPQTLPLLEKYENLMVLRTFSKAYGLAAFRIGYAIGDAKLIGQLEVARLPFNTSTVAQSVALAALEDQAFLQDCVQKNAEGLNQYYAFCKEYNVFYYPSQTNFIFLKLGIPGNEAFERLMKKGYIVRSGAAFGIDDGIRITVGLKEENDEIIELLKELVNEQVQKEETYS
What are the official names of this protein?
Histidinol-phosphate aminotransferase 1, Imidazole acetol-phosphate transaminase 1.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: CATA1_SOLTU
Sequence: MDPSKYRPSSAYDTPFLTTNAGGPVYNNVSSLTVGPRGPVLLEDYYLIEKLATFDREKIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGAQTPVICRFSTVVHERGSPESIRDIRGFGVKFYNRGGNFDLVGNNVPVFFNRDAKSFPDTIRALKPNPKSHIQEDWRTLDFFSFLPESLHTFAFFYDDVCLPTDYRHMEGFGVHAYQLINKEGKAHYVKFHWKPTCGVKCMSEEEAIRVGGTNHSHATKDLYDSIAAGNYPEWKLFIQTMDPEDVDKFDFDPLDVTKTWPEDLLPLIPVGRLVLNRNIDNFFAENEQLAFNPGHIVPGIYYSEDKLLQTRIFAYADTQRHRIGPNYMQLPVNAPKCGHHNNHRDGAMNMTHRDEEVDYFPSRFDPCRPAEQYPIPACVLNGRRTNCVIPKENNSKQAGERYRSWESDRQDRYINKWVESLSDPRVTHEIRSIWISYLSQADKSCGQKVASRLTVKPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome. Glyoxysome.
Protein: QUEC_ECOLC
Sequence: MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPLMWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCSHCAACNLRANGLNHYLADKPTVMAAMKQKTGLR
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RL1_XANC5
Sequence: MAQSKRVKAITAAVVPGKTYAFEDAIKILKTATKAKFVESIDVAVRLGVDAKKSDQQVRGSTVLPAGTGKSVRVAVFAPAGAKADEALAAGAEAVGMDDLAEKMQAGDLNYDVVIATPDAMRVVGKLGTLLGPRGLMPNPKVGTVSANPGEAVKNAKSGQVRYRTDKAGIIHCTIGKASFDDEALKSNLQALLLDLVKAKPATSKGTYLQKVSVSSTMGPGVTVDQSSLSLK
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: P53_SHEEP
Sequence: MEESQAELGVEPPLSQETFSDLWNLLPENNLLSSELSAPVDDLLPYSEDVVTWLDECPNEAPQMPEPPAQAALAPATSWPLSSFVPSQKTYPGNYGFRLGFLHSGTAKSVTCTYSPSLNKLFCQLAKTCPVQLWVDSPPPPGTRVRAMAIYKKLEHMTEVVRRSPHHERSSDYSDGLAPPQHLIRVEGNLRAEYFDDRNTFRHSVVVPYESPEIESECTTIHYNFMCNSSCMGGMNRRPILTIITLEDSRGNLLGRSSFEVRVCACPGRDRRTEEENFRKKGQSCPEPPPGSTKRALPSSTSSSPQQKKKPLDGEYFTLQIRGRKRFEMFRELNEALELMDAQAGREPGESRAHSSHLKSKKGPSPSCHKKPMLKREGPDSD
What is the function of this protein?
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type.  Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process.  One of the activated genes is an inhibitor of cyclin-dependent kinases.  Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.  Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity).  However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity).  In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription.  Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression.  Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1.  LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation.  Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
What are the official names of this protein?
Cellular tumor antigen p53, Tumor suppressor p53.
What is the protein family that this protein belongs to?
Belongs to the p53 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Nucleus, PML body. Endoplasmic reticulum. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Interaction with BANP promotes nuclear localization. Recruited into PML bodies together with CHEK2. Translocates to mitochondria upon oxidative stress. Translocates to mitochondria in response to mitomycin C treatment (By similarity).
Protein: EFTS_THEFY
Sequence: MANYTAADVKRLRELTGAGMMACKKALEESGGDFDKAIEALRIKGAKDVGKRAERTAANGLIALAQDGDTSAVLLELNCETDFVAKNDKFQELAAELAGFVARTSPSDVPSLLSADYADGKTVSQVIEELSAVIGEKIELRRFAKVEGAYVASYMHKSDPDLPPTLGVLVELDKPNAEVAKDLAQQIAALAPKYISRDDVPADVVENERRIAKATAREEGKPEQALPKIVEGRLNGFFKDATLLGQPFVKDNKKTIQQVVDEAGVTVRRFVRFKVGQA
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YOT9_CAEEL
Sequence: MSSTAEEMAAAFEQTGGPDLTTGSGKRTKSDRVEHKHASQPGGDTRKVVQTASNGEAKRKEK
What are the official names of this protein?
Uncharacterized protein ZK632.9.
Protein: IMP17_NAUMA
Sequence: YYEEYVDGQGMVVR
What are the official names of this protein?
Uncharacterized protein IMPP17.
Protein: NU3M_SALSA
Sequence: MNLITTIIAITITLSAVLATISFWLPQMTPDAEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLTTPALTLAWSAAVLALLTLGLIYEWTQGGLEWAE
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 3, NADH dehydrogenase subunit 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: GLB4_TYLHE
Sequence: DTCCSIEDRREVQALWRSIWSAEDTGRRTLIGRLLFEELFEIDGATKGLFKRVNVDDTHSPEEFAHVLRVVNGLDTLIGVLGDSDTLNSLIDHLAEQHKARAGFKTVYFKEFGKALNHVLPEVASCFNPEAWNHCFDGLVDVISHRIDG
What are the official names of this protein?
Extracellular globin-2C, Erythrocruorin, Extracellular globin IIC.
What is the protein family that this protein belongs to?
Belongs to the globin family.
What are the subcellular locations of this protein?
Secreted.
Protein: KDSB_SALPB
Sequence: MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATIPWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDLERVRAEMR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADK_FINM2
Sequence: MNNNSKIINIYVNDNQKSLETALIVKDKLEQKGFKPTFDFDENALINLCIGGDGAFLRAVHKYEFSTIPFVGINTGHLGFYQEILIPNIDKFISDLINENYGIEKISLLESKTAIRNSSKTYTHKALNEFVVKSDDSSIVYLDVYIDDNHLESFAGDGIIVSTPSGSTAYNFSAGGSVLYHGLDGFQVTPLAPINSKAYRSLLNSLVVPSKSNVTLYFRDHNFDRKSSIVLADGLNRSYDNVDYVNFTYSDQYINKLVFLKDWYWLNIKDKFL
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYC4_ALIFS
Sequence: QEDIEAGKQKSATCTACHGQEGNST
What is the function of this protein?
Diheme, high potential cytochrome c believed to be an intermediate electron donor to terminal oxidation systems.
What are the official names of this protein?
Putative cytochrome c4, Cytochrome c551.
What are the subcellular locations of this protein?
Periplasm.
Protein: VPS50_CHICK
Sequence: MQKIKSLMTRQGLRSPQESVHDLSPIENLRFPTKEELRESWEEPTDPQAQQEIINSIEEVYFSNDAFDIVKYELERLPPVLSLQELEEYRDKLKQQQAAELERVTSLQNGLQLAAVICADGRRHLNIAKEGFTQTSLGLLANQRKRQLLIGLLKSLRTIKTLQRTDVRLSEMLEEEDYPGAIQLCLECQKAASTFKHYSCISELNSKLQDTLEQIEEQLDVALSKICKNFDINHYTKVQQAYRLLGKTQTAMDQLHMHFTQAIHNTVFQVVLGYVELCAGNTDTKFQKLQYKDLCTHITSDSYIPCLADLCKALWEVMLSYYRTMQWHENHDQDEAATVSSVSDGSSVVGTEENSFDRSYVKKKLEHGLSRIWQDVQLKVKTYLLGTDLSNFKYDDFIFVLDVISRLMQVGEEFCGSKSEVLQESIRKQSVNYFKTYHRTRLEELRMFLENETWELCPVKSSFDILQLHEFKFMVQSRSPSVSPSKQPASAISTTVTLFEQYCNGGNPFEIQADSKDDETEDVLASNGYESDEQEKSAYQEYDSDSDVPEELKRDYVDEQTGDAPMKSVSRETLRSRKKSDYSLNKGNAPILTNTTLNVVRLVGKYMQMMNILKPIAFDVIHFMSQLFDYYLYAVYTFFGRNDTFESTGLGLSSSRLRTTLNRIQESLIDLEVSADPTGTLTAAEERKEKVPSPHLSHLVVLTSGSSLYGLAERVVATESLVFLAEQFEFLQPHLDAVMPAAKKPFLQQFYSQTVSTANELRKPVYWIVAAKAIDYEQMLLLMANVKWDVKEIMSQHNVYVDSLLKEFEEFNRRLNEVSKRVRIPLIVSNILWEHCMRLANRTLVEGYANVKKCSNEGRALMQLDFQQFLMKLEKLTDIRPIPDKEFVETYIKAYYLTENDMERWIKEHREYSTKHLTNLVNVCLGSHINKKARQKLLAAIDDIDRPKR
What is the function of this protein?
Acts as component of the EARP complex that is involved in endocytic recycling.  The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
What are the official names of this protein?
Syndetin, Coiled-coil domain-containing protein 132, EARP/GARPII complex subunit VPS50.
What is the protein family that this protein belongs to?
Belongs to the syndetin family.
What are the subcellular locations of this protein?
Recycling endosome. Membrane. Note=Associates with membranes in an EIPR1-dependent manner.
Protein: GLYA_ACIRA
Sequence: MFANISIAEFDPELAQAITNEDARQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYGGCEYVDIIEQLAIDRAKELFGADYANVQPHAGSQANSAVYLALLNPGDTVLGMSLAHGGHLTHGAKVSFSGKTYNAIQYGLNPETGEIDYEEVERLALEHKPRMIVAGFSAYSQIVDWQRFRDIADKIGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRSGLILAKANEEIEKKLQSAVFPGNQGGPLVHAVAAKAICFKEAMAPEYKAYQQQVVKNAQAMAEVLIERGYDVVSGGTKNHLFLLSLIKQDITGKDADAWLGAAHITVNKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRDLASWIADILDSKGDEAVINTVKAKVEAVCAKFPVYAK
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IRC18_YEAST
Sequence: MKVQMIERIFLIQLCLLTVVLASSRAVVEFESTGTKLVNSLRVLAAYSQSSVCVDEKISGIERQIEEVKDMYGNHSFILKGLNGILNNKVNMLTREIQMETVGNNTFETETGKLTKGLNRAVNISPFKYIKKFKTVSTKKFESLLNKYDLVAKKGGELTEEQKKKKEVLSRISRVVAATTIEAGLAQGVVDLCITVTTSLCLVSASIGGVGFLIWLTIIYQALT
What is the function of this protein?
Involved in spore wall assembly.
What are the official names of this protein?
Outer spore wall protein 6, Increased recombination centers protein 18.
What is the protein family that this protein belongs to?
Belongs to the OSW4/6 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.