PharMolix/UniProtQA huggingface dataset:
Protein: CLPX_BACCN
Sequence: MFKFNDEKGQLKCSFCGKTQTQVRKLVAGPGVYICDECIELCTEIVQEELAKDEEVEFKDVPKPIEIREILDEYVIGQDNAKKALAVAVYNHYKRINSNSKIDDVELAKSNIALIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEPIIKRRLGEKVIGFGSEKKNAEVNEKHVLSHVLPEDLLRFGLIPEFIGRLPVIANLEPLDEDALVDILTKPKNALVKQFQKLLELDDVELEFEEGALIEIAKKAIERKTGARGLRSIIEGLMLDVMFELPSRKDIEKCILTRETVANNAPPKLVLQDGTVLDTKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: NDK_FRATO
Sequence: MTKQRTLSIIKPDAVEKNVIGEIYSRFEKAGLRIIAAKMKHLSKAEAEGFYAVHKDRPFFSALVEFMISGPVMIQVLEGENAIAKNRELMGATNPKEAKAGTIRADFADSIDANAVHGSDAEDTAAQEIRYFFSDTEIFG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS4_SHEDO
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKLETAPGQHGARKPRLSEYGTQLREKQKVRRIYGVLEKQFRNYYKEAARLKGNTGENLLQLLETRLDNVVYRMGFGATRAESRQLVSHKTVLVNGRVVNIPSFKVSANDVVSIREKSRTQARIKASLEVAAQREKPTWVEVDNTKMEGAFKRLPERSDLSADINEQLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MSRA_XANCB
Sequence: MLGIGAFKQRMPRSGEALPGRTQALPLHNTHLINGHPLRGEFTGLAQVQFGLGCFWGAERKFWNVPGVYTTAVGYAGGKTPNATYSEVCSGQTGHTEAVLVVYDAQAVSFEQLLRTFWESHDPTQGMQQGNDVGTQYRSAIYCSTQAQYDAAIASRDAYQQQLTAAGYGDITTEILYPAPTFYYAEDDHQQYLAKHPNGYCGLGGTGVSCPIGLDA
What is the function of this protein?
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation.  Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrA, Protein-methionine-S-oxide reductase, Peptide-methionine (S)-S-oxide reductase, Peptide Met(O) reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrA Met sulfoxide reductase family.
Protein: PSBL_PROM5
Sequence: MQVNENPNKVPVELNRTSLYLGVLSVLVLGILFSSYFFN
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization.
What are the official names of this protein?
Photosystem II reaction center protein L, PSII-L.
What is the protein family that this protein belongs to?
Belongs to the PsbL family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: HOA_STRCO
Sequence: MNPPTVTVHDSTLRDGQHAVRHQLDADQIRAYAVAADTAGVPVLEVGHGNGIGASSRQVGLSKTDDATMLTTAREAMPHSRLATLMLPGWATSTDLRSAIRHGVDIVRVAAHCTEADVTERHLGVIRDLGAEAQGVLLMSHLAAPDELAAQCQRMVGYGAQAVCIFDSAGTYLPEDVTARITAITTAVDVPVAFHGHNNLGMAVANSLAAVRAGARVLDACARGFGAGAGNTQLEVLVAVLERYGHPTGIDLRLVAQAADLAERTLMPAPPTIDSTSLVSGLAGVFSGFKKPVLAAAQRAGVSPWDVFVELGRRRVLAGQEDLIPDAINTLTSMGERP
What are the official names of this protein?
4-hydroxy-2-oxovalerate aldolase, HOA, 4-hydroxy-2-keto-pentanoic acid aldolase, 4-hydroxy-2-oxopentanoate aldolase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
Protein: LCMT1_ASPFU
Sequence: MSASQIPNLNTLRRGGGRGRLRGRGGFETGAPSEDRHGSRGLAAQDRVVQGTDNDASVSRLSAVEIGYLEDPFAKVLTPPGSGTRRLPIINRGTYVRTTAIDRLVARFLEGPSQTKKQIISLGAGSDTRVFRLLSSRSSASSSDLIYHEIDFSANTAAKIKFIRAAPLLQRTLGLGSAQNVAIPDSGDALHSPTYHLHPVDLRTLAASGSATTSRSPSSPNPAEKDQPPCPLQGVDPTLPTLLISECCLVYLSPREAADVVDYFTKTLFPASVPLGLIIYEPIRPDDAFGRTMVANLATRGIQLQTLHEYASLEAQRRRLREHGLHSGQAAADIDFIWERWVSEAEKERVARLEMLDEVEEWQLLARHYCVAWGWTSGAGEDTTVFDGWKEIDGQTGD
What is the function of this protein?
Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
What are the official names of this protein?
Leucine carboxyl methyltransferase 1, Protein phosphatase methyltransferase 1, [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. LCMT family.
Protein: Y1177_CLOBB
Sequence: MQKDVEYIELLDEQGEQIKFKVITYFQIDEINGEYVVVTPAENDECDEAFVLKVISDEDGNETLVSIEDEKEFDLVEEAYNLVMSEQD
What are the official names of this protein?
UPF0473 protein CLL_A1177.
What is the protein family that this protein belongs to?
Belongs to the UPF0473 family.
Protein: THIG_CITBB
Sequence: MTQTNDKLVIAGREFDSRLMVGTGKYADFQQMVRAIEVSGAQIITVAVRRVNISDRSKESLLDHIDLKKYTLLPNTAGCYTAEDAIRTCRLAREAGLSDFVKLEVLGDEKTLYPNNEELLKAAKVLLAEGFTVLPYTSDDPIICKKLEDMGCAAVMPLGAPIGSGLGIRNPYNIQIILESVKVPVIVDAGVGTASDAAIAMELGCHGVLMNTAIAGAKDPVAMAEAMNCAVRAGRLAYLAGRIPRKLYASASSPLAGLIG
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_METPB
Sequence: MAKKSSVEKNNHRKELVKRFAEKRKALLAIANDESREMEERFEARLKLAELPRNSSATRIRNRCEMTGRPRAYYRKLGISRVALRELGNRGLIPGLVKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: PTHP_STAAW
Sequence: MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNLKSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK
What is the function of this protein?
P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes.  Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources.  P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity (By similarity).
What are the official names of this protein?
Phosphocarrier protein HPr, Histidine-containing protein.
What is the protein family that this protein belongs to?
Belongs to the HPr family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_RHOCS
Sequence: MTRSVWKGPFVDGYLLKKAEKARASGRNEIIKIWSRRSTILPQFVGLTFGVYNGQKFLPVLVTENMIGHKFGEFSPTRTFYGHAADKKAKRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: LOLD_XANOR
Sequence: MNEIREAVVQTPEQATAVIRAEALAKTYAEGKMRTPVFDGLDLSVATGETVAIVGASGAGKSTLLHLLGGLDIPTAGEVYVAGERMSALSDAQRGKLRNQSLGFVYQFHHLLPEFTALENVMMPVLLSGKNVAVAKGQALQLLESVGLGHRIDHKPSELSGGERQRCAVARALVNKPGCVLGDEPTGNLDDKTAGTVFELMLELNRAQRTSLVLVTHDRGLARRLDRVLELHQGKLRELAPSAV
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: Y903_SYNY3
Sequence: MALALFDISDQPINTQPLISALQCDQAGALVTFAGWVRNHNDGKQVDSLEYQVYRELAINEGFKIIAEAKEKYDLHQAIAVHRSGHLKIGETAVWVGTVASHRQAAFQGTQYVIDQIKLRLPIWKKEHYFDYPATWVYCCHHHGS
What are the official names of this protein?
Uncharacterized protein slr0903.
What is the protein family that this protein belongs to?
To M.jannaschii MJ0717.
Protein: NBLA2_SYNY3
Sequence: MINNEAFNLSLEQKFQLQCLQQEYQELDREQTVNYLLETMQQIMVRDNLIRDLMKNSLLP
What are the official names of this protein?
Phycobilisome degradation protein NblA homolog 2.
What is the protein family that this protein belongs to?
To Synechococcus PCC 7942 NblA and some, to chloroplast ycf18.
Protein: U85A2_ARATH
Sequence: MGSHVAQKQHVVCVPYPAQGHINPMMKVAKLLYAKGFHITFVNTVYNHNRLLRSRGPNAVDGLPSFRFESIPDGLPETDVDVTQDIPTLCESTMKHCLAPFKELLRQINARDDVPPVSCIVSDGCMSFTLDAAEELGVPEVLFWTTSACGFLAYLYYYRFIEKGLSPIKDESYLTKEHLDTKIDWIPSMKNLRLKDIPSFIRTTNPDDIMLNFIIREADRAKRASAIILNTFDDLEHDVIQSMKSIVPPVYSIGPLHLLEKQESGEYSEIGRTGSNLWREETECLDWLNTKARNSVVYVNFGSITVLSAKQLVEFAWGLAATGKEFLWVIRPDLVAGDEAMVPPEFLTATADRRMLASWCPQEKVLSHPAIGGFLTHCGWNSTLESLCGGVPMVCWPFFAEQQTNCKFSRDEWEVGIEIGGDVKREEVEAVVRELMDEEKGKNMREKAEEWRRLANEATEHKHGSSKLNFEMLVNKVLLGE
What are the official names of this protein?
UDP-glycosyltransferase 85A2.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: BGAL_YERPG
Sequence: MQLSLPQILSRRDWENPQITQYHRLEAHPPFHSWRDVESAQKDRPSPQQQTLNGLWSFSYFTQPEAVPEHWVRCDLAEAKPLPVPANWQLHGYDAPIYTNIQYPIPVNPPRVPDLNPTGCYSRDFTLEPSWLASGKTRIIFDGVSSAFYLWCNGQWVGYSQDSRLPAEFDLTPYLQAGSNRIAVLVLRWSDGSYLEDQDMWRMSGIFRDVKLLHKPEIHLRDIHIMTHLSPEFTSANLEVMAAVNIPSLQLNDPQVTGSYQLRVQLWLADKLVASLQQPLGTQAIDERGPYTDRTQLVLRIDQPLLWSAEQPTLYRAVVSLLNHQQELIEAEAYDVGFRQVAIHQGLLKINGKAVLIRGVNRHEHHPQTGQAIDEESLLQDILLMKQHNFNAVRCSHYPNHPLWYRLCDRYGLYVVDEANIETHGMQPMSRLSDDPSWFSAFSERVTRMVQRDRNHPCIIIWSLGNESGHGATHDALYRWIKTNDPTRPVQYEGGGANTLATDILCPMYARVDEDQPFPAVPKWSIKKWIGLPNESRPLILCEYAHAMGNSFGGFARYWQAFRQYPRLQGGFIWDWVDQSLTHHNDHGQPYWAYGGDFGDTPNDRQFCMNGLVFPDRSPHPSLYEAQCAQQFFQFSLLSTTPLVINITSEYLFRESDNEQLYWRIMLEGESVLEGSQPLNLSPESSQCYRLAEKLPTLNKPGQLWLNVEIRQPKETPWSPAQHRSAWHQWRLPQPLFSPSSDLTNATAHYAPQLQHNLQLQHDLQLQQDEQHIKVTYQQQCWQFSRQTGRLAQWWVADKPMLLRPLQDQFVRAPLDNDIGISEATHIDPNAWVERWKKAGMYQLQQRCLSLHVDHLSHSVQISAEYGYEFEQEPLLHSHWVYRFDRHGRMTIDVNVRIATSLPAPARIGMCCQLADISPTVEWLGLGPHENYPDRQLAAQYGHWSLPLEQMHTAYIFPSENGLRCNTHTLNYGRWTLTGDFHFGISRYSTQQLMVTSHQHLLEPEEGTWLNIDGFHMGVGGDDSWSPSVHIDDILTRETYQYQICWQYKV
What are the official names of this protein?
Beta-galactosidase, Beta-gal, Lactase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 2 family.
Protein: COXZ_CERSP
Sequence: MSLSPHQKTAGGLVLVVAVMGAASFAAVPFYNWFCRVTGFAGTTAVATEAPAEVLDRTVKVRFDASREAGMPWEFRPLQREMKLKIGETGLAFYEAYNPTDRTVAGTASYNVTPDAAGGYFAKIACFCFTEQVLAPGERVEMPVTFYVDPAIIDDPDGRYVRQITLSYTFHETALTEEQAALAAESATDVN
What is the function of this protein?
Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I.
What are the official names of this protein?
Cytochrome c oxidase assembly protein CtaG.
What is the protein family that this protein belongs to?
Belongs to the COX11/CtaG family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: NUDI_SALPC
Sequence: MRQRTIVCPLIQNDGCYLLCKMADNRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLILSDITPWTFRDDIRVKTYADGRQEEIYMIYLIFDCVSANRDICINDEFQDYAWVKPEELALYDLNVATRHTLALKGLL
What is the function of this protein?
Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP).
What are the official names of this protein?
Nucleoside triphosphatase NudI, Nucleotide diphosphatase NudI, Pyrimidine deoxynucleoside triphosphate diphosphatase, dCTP diphosphatase, dTTP diphosphatase, dUTP diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudI subfamily.
Protein: SOMA_LEPOS
Sequence: MASGFLLCPVLLAVFFMSPVEVGAFPLYSLFTNAVIRAQHLHQLAADIYKDFERTYVPEEQRQSSKSSPSAICYSESIPAPTGKDEAQQRSDVELLRFSLALIQSWISPLQTLSRVFSNSLVFGTSDRIFEKLQDLERGIVTLTREIDEGSPRIAAFLTLTYEKFDTNLRNDDALMKNYGLLACFKKDMHKVETYLKVMKCRRFVESNCTL
What is the function of this protein?
Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes.  Implicated as an osmoregulatory substance important for seawater adaptation.
What are the official names of this protein?
Somatotropin, Growth hormone.
What is the protein family that this protein belongs to?
Belongs to the somatotropin/prolactin family.
What are the subcellular locations of this protein?
Secreted.
Protein: QUEA_BACHK
Sequence: MDINLFDFHLPEELIAQVPLEERETSRLMVLDRETGDIEHKHFTDILSYLHEGDCLVLNETKVMPARLHGVKEDTGAHIEVLLLKQEEGDKWETLVKPAKRVKEGTVISFGEGKLKATCTGTADQGGRQLEFSYDGIFYEILDELGEMPLPPYIKETLEDRDRYQTVYAKEIGSAAAPTAGLHFTEELLEKLKQKGVELAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAALLNRVKENGGRIITVGTTSTRTLETIATDHDGKLCAASGWTDIFMYPGYEFKAIDGLITNFHLPKSTLIMLVSAFANRDNVLHAYNEAVKEKYRFFSFGDAMFVASHAKMGNK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDC_LEPIN
Sequence: MEDRQTRLFLALILSMGIWMGVNYFFFPNTSTKKNTETKQTQSDKTSENTKQQITSGKTKESNSADPVVQKEKITPFDTKKSFIVTDSYIVEFSSLGGKISKFYMKDFTGPNGELIQVARKNPETVVVDGKSYQAVELSRDKGFDFNFSDSLVEISDSPWNYIQFSLTEDKINHSISFSAVSPDRSYQLKKEFRFYPSENYFKLSISIINFSKEKLSFASQKNVRYLRTFGSLGPYPKDRPLSDRDTANFFRFYYLGGSFQDTLDGSSSVGFWSSVGNFFTGNSGTDESFSIKTDKESGVDFAGTGSRYFIAVADPLDHKPHGIVLDNRPKNESGAVLVYDNILLNPGENYNLDFASYIGIRESEGMAFKNPELDPSQSKNSPFVGLSSDLNKSFNQGITTPFRNGIIWILKQIYRFTIPNYGWSIIIFAILFKLVFYPLNQKQADSMKKMQELSPQLKTINEKFANDPKMRQQKTMELYKKNNVNPVGGCLPMVIQIPIFIALYTAFSDTIDLWNSPFLWVKDLSEPDVIWTSPAIPYFTQTGIGLNLLALLMVGTQVFQTRMTSVSMDPNQKMLMYVMPVMMLYIFWNMPSGVTLYWTFQNVLSIGQQWITNHLKKTEEKKKAKV
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEL_TORDE
Sequence: MINFSLLTSIVLLASKVVGVSPSYNGLGLTPQMGWNNWNTFACNVSEDLLLSTVDRIAALGLRDIGYHYVILDDCWSDGRDSDGMLVPDSTKFPNGMKHVADYLHGKDFLFGMYSSAGEYTCAGYAGSLDHEEDDAAFFAKNEVDYLKYDNCYNRGQFGTPETSFNRYRAMSEALNKTERPIFYSLCNWGQDLTFYWGSGIANSWRISGDITAEFDRPDSRCPCDGDEYDCPYAGFHCSIMNILNKAAPMGQNAGVGGWNDLDCLEVGVGNLTDDEEKAHFSMWAIVKSAMVIGADVRNLKPSSFSIYSQASVLAINQDPAGAPAIRVWRRYVPETDQHGQGEVQLWSGPLDNGDRVVALLNGGAKERPMVAYLEDIFIDSFVGSEELSSTWNVYDLWANRIDDSTASQILVGNRTANGLLYNATQLSYADGLKANDTRLFGEKVGTIEPYGLLNVTVPAHGVGLFRLRRESRK
What are the official names of this protein?
Alpha-galactosidase, Alpha-D-galactoside galactohydrolase, MELt, Melibiase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 27 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MND1_BOVIN
Sequence: MSKKKGLSAEEKRTRMMEIFYETKDVFQLKDMEKIAPKEKGITTMSVKEVLQSLVDDGMVDCERIGTSNYYWAFPSKALHARKRKLEVLDSQLSEGNQKYANLQKSIEKAKVGRHETEERTMLAKELSSLRDQREQLKAEVEKYRECDPQVVEEIRQANQVAKEAANRWTDNIFAIKSWAKRKFGFEENKIDKNFGIPEDFDYID
What is the function of this protein?
Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.  Stimulates both DMC1- and RAD51-mediated homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks (By similarity).
What are the official names of this protein?
Meiotic nuclear division protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the MND1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPO10_METAR
Sequence: MIPVRCFTCGKVISEVWEEYKARVEERKMNLQHGEVLKVGDILDDLGVERYCCRRMLLSHVELVDVLAPYQ
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit N.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACH1_YARLI
Sequence: MSAVLKQRIRYKPYLDKIRTAAQCVDLFGAKPNQYIGWSGFTGVGAPKVVPDAVSKHVEENNLQGHENWRYNLFVGASAGMEIESRWANNNMIARRSPHQVGKPIAAAINEGRTDFFDKHLSMWAQDLTYGFYTRDKKENSLDIAVIEATAITEDGHLIPGPAVGASPEIVHMADKIIIELNTKTPSFEGLHDINMPVLPPFRQPYQITDVSQKMGTPYIPLDPSKVVAIVESEFADVVGANSPADEGSKAIAANLIELFQQEVKAGRLPENLLPLQSGIGNIANAVVEGLADASFKDLNVWTEVLQDSFLDFFESGNLNFATATSIRLTEDGFKRFFDNWDEFSKKLLLRSQVVSNNPEIIRRLGVIAMNTPVEVDIYAHANSTCVNGSKMLHGLGGSGDFLRNAKLSIMHTPSARPSKTDPLGISCIVPFATHIDQTEHDLDIVVTEQGLADLRGLSPKERSREMINKCAHPSYRDQLLAYVEQAEFECAKSRSLHEPHVLKNAFKMHTNLAENGTMRLDKW
What is the function of this protein?
Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation.
What are the official names of this protein?
Acetyl-CoA hydrolase, Acetyl-CoA deacylase, Acetyl-CoA acylase.
What is the protein family that this protein belongs to?
Belongs to the acetyl-CoA hydrolase/transferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGD_BACSU
Sequence: MFNNQMLGVIDETTYKHSLQDLTAQRSLGAIPFAGRYRLIDFMLSNMVNADIRSVAIFPKYRYRSLMDHLGAGKEWDLHRKKDGLFFFPSPHLHHEYDEFGSFRQFSDHLDYFHRSTQQYAVISNSHTVCNIQFQYVLKRHQEVGCDVTEVFQDGQSLQIYIMSTTLLKDLIYGHSEKGYKTIQEAVEKESSALTICPYEYSGYAAVIDSVEKYYTHSMELIQPRFWQQVFLPQQPIYTKVKDEPPTKYGKHSTVKNSLVANGCVLEGEVENCILFRAVHVGKGTKLKNCIIMQKTQIGEDCLLEQVISDKDVKIGKATEAAGTAEQPLVLRKGLVQGELMNS
What is the function of this protein?
Required for the synthesis of glycogen.
What are the official names of this protein?
Glycogen biosynthesis protein GlgD.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: SSUB2_PSEF5
Sequence: MTAQQPPRLLQGIPLAVRKLQKTFGSRQVLREIDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLDQPSAGELLAGSAPLSAAIEDTRLMFQEARLLPWKKVIDNVGLGLKGNWRPQALQALEAVGLADRAQEWPAALSGGQKQRVALARALIHQPRLLLLDEPLGALDALTRIEMQQLIERLWQQHGFTVLLVTHDVSEAVAIADRVILIEDGEVGLDLHVELPRPRVRGSHRLAALETEVLNRVLSLPGSPPEPEPVSPLPTQLRWAL
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CRCB_ACIAC
Sequence: MLLNIAVICLAACVGALMRWGFALWLNPGGLIPWGTLAVNLIGGYCIGIALAVFTSRPDIDPAWRLLVITGFLGTLTTFSSFSGEVVTMLMQQRFGLAFGTIALHLGGSLALTWAGMRSALWWLAR
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DMR18_CRYX8
Sequence: MSTTYIPYRLDGKVALVTGSGRGIGAAIATQLGRLGAKVVVNYANASEAAEKVVSEIKSFGTDAVAFKADVRQVAQTAKLMDDAVAHFGSLDIVCSNSGVVSFGHIGEVTEEEFDRVFSLNTRGQFFVAREAYRHLNNGGRIILMSSNTAKDFSVPKHSLYSGSKGAIDSFVRVFSKDCGDKKITVNAVAPGGTVTDMFHDVSQHYIPGGEKYTAEERQEMAAHASPLTRNGFPVDIARVVGFLASNEAEWVNGKILTVDGGAA
What is the function of this protein?
Short chain dehydrogenase/reductase; part of the gene cluster that mediates the biosynthesis of the dimeric xanthones cryptosporioptides (PubMed:30996871).  The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase dmx-nrPKS (Probable).  The atrochrysone carboxyl ACP thioesterase dmxR1 then breaks the thioester bond and releases the atrochrysone carboxylic acid from dmx-nrPKS (Probable).  Atrochrysone carboxylic acid is decarboxylated by the decarboxylase dmxR15, and oxidized by the anthrone oxygenase dmxR16 to yield emodin (Probable).  Emodin is then reduced to emodin hydroquinone by the oxidoreductase dmxR7 (Probable).  A-ring reduction by the short chain dehydrogenase dmxR18, dehydration by the scytalone dehydratase-like protein dmxR17 and probable spontaneous re-oxidation, results in overall deoxygenation to chrysophanol (PubMed:30996871).  Baeyer-Villiger oxidation by the Baeyer-Villiger monooxygenase (BVMO) dmxR6 then yields monodictylactone in equilibrium with monodictyphenone (PubMed:30996871).  In the case of the cryptosporioptides biosynthesis, monodictylactone is reduced at C-12 to an alcohol (by the short chain dehydrogenases dmxR12 or dmxR8) and hydroxylated at C-5 by dmxR9, yielding the electron-rich aromatic which could eliminate H(2)O to form the ortho-quinonemethide, followed by tautomerisation to paraquinone and complete the formal reduction to produce the 10-methylgroup (Probable).  Conjugate addition of C-4a-OH to the resulting paraquinone by the monooxygenase dmxR10 then gives cyclohexadienone, which is then reduced at C-5 by the short chain dehydrogenase dmxR3 to give the dihydroxanthone (Probable).  The 6,7-epoxide in the cryptosporioptides could be introduced by the cytochrome P450 monooxygenase dmxL3 (Probable).  The highly reducing PKS dmxL2 manufactures butyrate, which is further carboxylated by dmxL1 to form ethylmalonate (PubMed:30996871).  It is not yet clear whether the carboxylation occurs while the butyrate is attached to the ACP of dmxL2, but this unusual fungal metabolite could then be esterified to O-5 by the O-acetyltransferase dmxR13 (PubMed:30996871).  Finally, dimerization performed by dmxR5 gives the observed dimers cryptosporioptides A, B and C as the final products of the pathway (PubMed:30996871).
What are the official names of this protein?
Short chain dehydrogenase/reductase dmxR18, SDR dmsR18, Dimeric xanthone biosynthesis cluster protein R18.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.