PharMolix/UniProtQA huggingface dataset:
Protein: RSGA_THENN
Sequence: MILRRRGIVLSFHSNMVTVEDEETGERLLCKLRGKFRLQNLKIYVGDRVEYTPDGTGSGVIENVLHRKNLLVKPHVANVDQAILVVTVKMPETSTYIIDKFLVLTEKNELETVLVINKMDIYDEEDLEKVKELERIYSKLYPIVKTSAKTGMGIEELKKYLKGKISTMAGLSGVGKSSLLNAINPGLKLRVSEVSQKLQRGRHTTTSAQLLRFDFGGYVVDTPGFANLEIGDIEPEELKYYFKEFNEKQCFFSDCNHIDEPECGVKEAVENGEIAESRYENYVKMFHELLGRGKS
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PBPA_NEIGO
Sequence: MIKKILTTCFGLFFGFCVFGVGLVAIAILVTYPKLPSLDSLQHYQPKMPLTIYSADGEVIGMYGEQRREFTKIGDFPEVLRNAVIAAEDKRFYRHWGVDVWGVARAAVGNVVSGSVQSGASTITQQVAKNFYLSSEKTFTRKFNEVLLAYKIEQSLSKDKILELYFNQIYLGQRAYGFASAAQIYFNKNVRDLTLAEAAMLAGLPKAPSAYNPIVNPERAKLRQKYILNNMLEEKMITVQQRDQALNEELHYERFVRKIDQSALYVAEMVRRELYEKYGEDAYTQGFKVYTTVRTDHQKAATEALRKALRNFDRGSSYRGAENYIDLSKSEDVEETVSQYLSGLYTVDKMVPAVVLDVTKKKNVVIQLPGGRRVALDRRALGFAARAVDNEKMGEDRIRRGAVIRVKNNGGRWAVVQEPLLQGALVSLDAKTGAVRALVGGYDFHSKTFNRAVQAMRQPGSTFKPFVYSAALSKGMTASTVVNDAPISLPGKGPNGSVWTPKNSDGRYSGYITLRQALTASKNMVSIRILMSIGVGYAQQYIRRFGFRPSELPASLSMALGTGETTPLKVAEAYSVFANGGYRVSSHVIDKIYDRDGRLRAQMQPLVAGQNAPQAIDPRNAYIMYKIMQDVVRVGTARGAAALGRTDIAGKTGTTNDNKDAWFVGFNPDVVTAVYIGFDKPKSMGRAGYGGTIAVPVWVDYMRFALKGKQGKGMKMPEGVVSSNGEYYMKERMVTDPGLMLDNSGIAPQPSRRAKEDDEAAVENEQQGRSDETRQDVQETPVLPSNTDSKQQQLDSLF
What is the function of this protein?
Cell wall formation.  Synthesis of cross-linked peptidoglycan from the lipid intermediates.  The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).  Essential for cell wall synthesis.
What are the official names of this protein?
Penicillin-binding protein 1A, PBP-1a, PBP1a.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the transpeptidase family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein.
Protein: CLS1_BACCR
Sequence: MKKPIVQLLLIFTIVSIVLFLLNTSYISLYTFVGALWSITIVGISFVIFIENRSPQSTLAWFLVLALLPIIGVLLYAIFGRSRWRRKKHLHRSEEQRKLFREILEGRRLELLLTVPLNERSIHLTEVIQKFGGGPAADRTTTKLLTNGDQTFSEILRAIEQAKHHIHIQYYIYKSDEIGTKVRDALIQKAKDGVIVRFLYDGLGSNTLRRRFLQPMKEAGIEIVEFDPIFSAWLLETVNYRNHRKIVIVDGEIGFTGGLNVGDEYLGRSKKFPVWRDSHLKIEGKALYKLQAIFLEDWLYASSGLNTYSWDQFMNRQYFPGKEISNAEGAVQIVASGPSSDDKSIRNTLLAVMGSAKKSIWIATPYFIPDQETLTLLRLSAIAGIDVRILYPGKSDSIISDQASQSYFTPLLKAGASIYSYKDGFMHAKIVLVDDTIATIGTANMDVRSFELNYEIISVLYESKTVHDIKRDFEEDFKHSTEIKWNSFQKRSIKKRILESFMRLISPLL
What is the function of this protein?
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
What are the official names of this protein?
Cardiolipin synthase 1, CL synthase 1.
What is the protein family that this protein belongs to?
Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PSAC_RHDSA
Sequence: MSHSVKVYDTCIGCTQCVRACPCDVLEMVSWDGCKAGQIASAPRTEDCIGCKRCETACPTDFLSVRVYLGGETTRSMGLAY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: OTCC_RHIET
Sequence: MSFNLRNRSLLTVQDYTPREFRYLLDLARDLKRAKYARTEQEHLKGKEICLIFEKTSTRTRCAFEVACSDQGANVTYLDPSGSQIGHKESFKDTARVLGRMYDAIEYRGSAQKGVETLAKYAGVPVYNGLTDEYHPTQMIADVMTMREHSDKPIAEIKYAYVGDTRSNMGHSLLIVGCLLGMDVRICGPRSLWPSEEYMKIAKVLQQASGARLLVTEDPREAVKDVDFIHTDVWVSMGEPKEVWRERIKLLTPYQVNQDLMKATGNPQTKFMHCLPAFHDTETTLGKQIAEDYGMDNGLEVTNDVFESEANVAFEQAENRLHTIKALLVATLGD
What is the function of this protein?
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
What are the official names of this protein?
Ornithine carbamoyltransferase, catabolic, OTCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MCA1_ARATH
Sequence: MYPPPPSSIYAPPMLVNCSGCRTPLQLPSGARSIRCALCQAVTHIADPRTAPPPQPSSAPSPPPQIHAPPGQLPHPHGRKRAVICGISYRFSRHELKGCINDAKCMRHLLINKFKFSPDSILMLTEEETDPYRIPTKQNMRMALYWLVQGCTAGDSLVFHYSGHGSRQRNYNGDEVDGYDETLCPLDFETQGMIVDDEINATIVRPLPHGVKLHSIIDACHSGTVLDLPFLCRMNRAGQYVWEDHRPRSGLWKGTAGGEAISISGCDDDQTSADTSALSKITSTGAMTFCFIQAIERSAQGTTYGSLLNSMRTTIRNTGNDGGGSGGVVTTVLSMLLTGGSAIGGLRQEPQLTACQTFDVYAKPFTL
What is the function of this protein?
Cysteine protease that cleaves specifically after arginine or lysine residues.  Does not cleave caspase-specific substrates.  Acts as a positive regulator of cell death.  Required for both oxidative stress cell death response and hypersensitive cell death response mediated by immune response.
What are the official names of this protein?
Metacaspase-1, AtMC1, Metacaspase 1b, AtMCP1b, Protein LSD ONE LIKE 3.
What is the protein family that this protein belongs to?
Belongs to the peptidase C14B family.
Protein: FSCN2_HUMAN
Sequence: MPTNGLHQVLKIQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDGRWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRSRRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVAANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRGRRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVCHHRGSNQLDTNRSVYDVFHLSFSDGAYRIRGRDGGFWYTGSHGSVCSDGERAEDFVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY
What is the function of this protein?
Acts as an actin bundling protein.  May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis.
What are the official names of this protein?
Fascin-2, Retinal fascin.
What is the protein family that this protein belongs to?
Belongs to the fascin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell projection, stereocilium.
Protein: ATPA_SYNE7
Sequence: MVSIRPDEISSIIRQQIEQYSQDVKVENVGTVLQVGDGIARIYGLQQVMSGELVEFEDGTTGIALNLEEDNVGAVLMGEGRNIQEGSTVKATGKIAQIPVGDALVGRVVSPLGAPLDGKGEIAATENRLIESPAPGIIARRSVHEPMQTGITAIDAMIPIGRGQRELIIGDRQTGKTAIAIDTILNQKGEDVICVYVAIGQKASSVANIIEVLRERGALDYTVVVAANASEPATLQYLAPYAGAAIAEYFMCKGKATLVIYDDLTKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSDALGGGSMTALPVIETQAGDVSAYIPTNVISITDGQIFLSSDLFNSGLRPAINVGISVSRVGSAAQTKAIKKIAGTLKLELAQFDELAAFAQFASDLDKATQNQLARGQRLRELLKQPQFSPLILAEQVAVVYAGVKGLIDEIPVNQVTAFVSELRSYLKTSKPEFIEKVQSSKQLDDAAEALLKEAIAEVKKNILAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: HEMA_I76AK
Sequence: MLSIVVLLLLMAEGSSQNYTGNPVICMGHHAVANGTMVKTLTDDQVEVVTAQELVESQNLPELCPSPLRLVDGQTCDIVNGALGSPGCDHLNGAEWDVFIERPSAVDTCYPFDVPDYQSLRSILANNGKFEFIAEEFQWSTVKQNGKSGACKRANINDFFNRLNWLVKSDGNAYPLQNLTKINNGDYARLYIWGVHHPSTDTEQTNLYKNNPGRVTVSTKTSQTSVVPNIGSRPLVRGQSGRISFYWTIVEPGDLIVFNTIGNLIAPRGHYKLNNQKKSTILNTAVPIGSCVSRCHTDKGSLSRTKPFQNISRIAIGDCPKYVKQGSLKLATGMRNIPEKASRGLFGAIAGFIENGWQGLIDGWYGFRHQNAEGTGTAADLKSTQAAIDQINGKLNRLIEKTNEKYHQIEKEFEQVEGRIQDLEKYVEDTKIDLWSYNAEFLVALENQHTIDVADSEMNKLFERVRRQLRENAEDKGNGCFEIFHKCDNNCIESIRNGTYDHDIYRDEAINNRFQIQGVKLTQGYKDIILWISFSISCFLLVALLLAFILWACQNGNIRCQICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SYI_CLONN
Sequence: MYNKIETSGNFVNMEEKIAKLWKDKDVIQKSFDRNEDGEYFTFYDGPPTANGKPHVGHVLTRVMKDLIPRYKVMKGYKVLRKAGWDTHGLPVELEIEKKLGISGKPQIEEYGVEKFVKECKDSVFKYTSLWKDMSEKLGFWVDMDNPYVTYHNTYIESVWWALKTMWEKDLLYKGHRVTPYCPRCGTALSSHEVAQGYKDVKEATAFVKFKVKGEENKYILAWTTTPWTLPSNVALAINKAYDYVEVEQNGEHLILAKDLAEKVLEGEYKVVKEFKGEELVGTEYEQLFKFEVPDKKAFYVVHADYVTLTDGTGIVHTAPAYGEDDNMTGKKYDLPLINLVDGEGKFVDSVTPWKGMFVKKADPKILEFMKENGSLYKSEKFTHSYPHCWRCDTPLLYYPKDSWFVRMTSLRDKLLENNNKINWNPDNIRTGRFGKFLENVIDWGISRDRYWGTPLPIWECECGHRECIGSIEELKEKGINVPDDIELHKPYIDGVKLTCPHCGKEMTRTNEVIDCWFDSGSMPFAQHHYPFENKEVFEKTFPAQFISEAVDQTRGWFYSLLAISTALFDTNSYENCIVLGHVLDKHGLKMSKSKGNVVDPFDVLQNEGADATRWHFYTASAPWLPTRFSEDDVKETQRKFLSTLWNVYSFYVLYAELDQFNPLEYKDFVSENVMDKWILSKLNTLIKTVEEDLDNYKITEAALELEDFVDELSNWYVRRNRSRFWSTELTDDKIGAYKTLYTVLTTIVKVAAPFVPFMAEEIYQNLVVNLDKDAIESVHLCTWPEYDLSVVDNELEGQMDLAYKIVKLGRSARNGANIKNRQPLSEMLISTKSLPDYYGDIIKEELNIKKVEFGADLSKYVNFEIKPNLPVLGKAYGRYIPAIRKAISSMDQMELAQNINNGKSVFINVDGLDEQIELTENNLLVAMQGLEGFAFAGSSGVGVILETTITEELREEGFVREILSKVQNLRKESGFEVADKIKLYFAGNETLEVVIKKFEEHIKKETLAVLISYNEDREYVDSKINGEELKIAVEKQD
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SUFS_SALNS
Sequence: MTFPVEKVRADFPILQREVNGLPLAYLDSAASAQKPNQVIDAESAFYRHGYAAVHRGIHTLSAQATESMENVRKQASRFINARSAEELVFVRGTTEGINLVANSWGTENIRAGDNIIISEMEHHANIVPWQMLCERKGAELRVIPLHPDGTLRLETLAALFDDRTRLLAITHVSNVLGTENPLPDMIALARQHGAKVLVDGAQAVMHHAVDVQALDCDFYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMISTVSLTQGTTWAKAPWRFEAGTPNTGGIIGLGAAIDYVTSLGLDKIGDYEQMLMRYALEQLAQVPDITLYGPAQRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAWYGVPAMCRASLAMYNTHEEVDRLVAGLTRIHRLLG
What is the function of this protein?
Cysteine desulfurases mobilize the sulfur from L-cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules.  Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation.  Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine.  Selenocysteine lyase activity is however unsure in vivo.
What are the official names of this protein?
Cysteine desulfurase, Selenocysteine beta-lyase, SCL, Selenocysteine lyase, Selenocysteine reductase.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NOX5_HUMAN
Sequence: MNTSGDPAQTGPEGCRGTMSAEEDARWLRWVTQQFKTIAGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTISAAHWLTAPAPRPRPRRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAASAHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLLLLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGKVQVFFCGSPALAKVLKGHCEKFGFRFFQENF
What is the function of this protein?
Calcium-dependent NADPH oxidase that generates superoxide.  Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa.  May play a role in cell growth and apoptosis.  Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
What are the official names of this protein?
NADPH oxidase 5.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. SUBCELLULAR LOCATION: [Isoform v2]: Endoplasmic reticulum. SUBCELLULAR LOCATION: [Isoform v5]: Endoplasmic reticulum.
Protein: DDL_STRP3
Sequence: MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFIKTQQFSEKPSESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLRMPYIGTNVMSSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVETLARLTFPIFVKPANMGSSVGISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDFYDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLNELNTMPGFTQWSMYPLLWENMGLAYPDLIEELVTLAQEIFDQRESHLI
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTG_LEGPL
Sequence: MFDDLSNYRPANPALWQGRKDTANQERFFQKITFIDNQNELMTKDKKTIFLGFASDAGIKRNLGRTGAKLGPDQIKTQLAKLPCHNNKHYVDLGNVICENDELELSQSQFAQIVHFCHENGHQICAFGGGHEIAWAHYQGLSSLYPKLGVINFDAHFDLRPYKKGELGNSGTPFSQIATYCEEKKMPFHYCCIGVQKFGNTPSLFEKAKKLNVSYLSAEDLYEQSQAWQIAFLDDFILNLDHIYLTICLDVLAECYAPGVSAPQALGLSPWQIMPLLKYLIQSGKVVSLDIAELSPPLDSELKTARLAALIIAELLDTN
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: TLX1_MOUSE
Sequence: MEHLGPHHLHPGHAEPISFGIEQILNSPDQGGCMGPNSRLQDGDYGLGCLVPGAYTYGGGGSAAGAGAGGTGAYGAGGPGGPGGPAGGGGGACSMGPLPGSYNVNMDLAGGPGPGGDGGGGGAARRALSAAGVIRVPAHRPLAGAVAHPQPLATGLPTVPSVPAVPGVNNLTGLTFPWMESNRRYTKDRFTGLPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQNRRTKWRRQTAEEREAESEQANRILLQLQQEAFQKSLAQPLPADPLCVHNSSLFALQNLQPWSDDSTKITSVTSVASACE
What is the function of this protein?
Controls the genesis of the spleen.  Binds to the DNA sequence 5'-GGCGGTAAGTGG-3'.
What are the official names of this protein?
T-cell leukemia homeobox protein 1, Homeobox TLX-1, Homeobox protein Hox-11.
What are the subcellular locations of this protein?
Nucleus.
Protein: TCF20_MOUSE
Sequence: MQSFREQSSYHGNQQSYPQEVHSSSRIEEFSPRQAQMFQNFGGAGGGSSGTGSSSSGRRGTAAAAAAMASETSGHQGYQGFRKEAGDFYYMAGNKDTVAAGTPQPPQRRPSGPVQSYGPPQGSSFGNQYASEGHVSQFQAQHSALGGVSHYQQDYTGPFSPGSAQYQQQASSQQQQQQQQQQQQQQQQQQQQVQQLRQQLYQSHQPLPQTTGQPASGSSHLQPMQRPSTLPSSAGYQLRVGQFGQHYQSSASSSSSSSFPSPQRFSQSGQSYDGSYSVNAGSQYEGHNVGSNAQAYGTQSNYSYQPQSMKNFEQAKIPPGNQQGQQQQQQQPQPQQQQPQQQQQQQQQQQHPPQHVMQYTNAATKMPLQSQVGQYNQPEVPVRSPMQFHQNFSPISNPSPAASVVQSPSCSSTPSPLMQSGENLQCGQGNVPMSSRNRILQLMPQLSPTPSMMPSPNSHAAGFKGFGLEGVPEKRLTDPGLSSLSALSSQVANLPNTVQHMLLSDALTPQKKTSKRPSSSSKKADSCTNSEGSSQPEEQLKSPMAESLDGGCSSSSEDQGERVRQLSGQSTSSDTTYKCGASEKAGSSPTQGAQNEAPRLSTSPATRDEAASPGAKDTSLSSEGNTKVNEKTVGVIVSREAMTGRVEKSGGQDKGSQEDDPAASQRPPSNSGVKEISHTSLPQPDPPGGGSKGNKNGDNNSSNHNGEGNGPSSHSAVGPSFTGRTEPSKSPGSLRYSYKESFGSAVPRNVSGYPQYPSGQEKGDFGSHGERKGRNEKFPSLLQEVLQGYHHHPDRRYPRSAQEHQGMASGLEGTARPNILVSQTNELASRGLLNKSIGSLLENPHWGPWERKSSSTAPEMKQINLSDYPIPRKFEIEPPSSAHEPGGSLSERRSVICDISPLRQIVRDPGAHSLGHMGTDARIGRNERLNPSLSQSVILPGGLVSMETKLKSQSGQIKEEDFEQSKSQASFNKKSGDHCHPTSIKHETYRGNASPGAAAHDSISDYGPQDSRSTPMRRVPGRVGSRETMRGRSSSQYHDFAEKLKMSPGRSRGPGGDPHHMNPHMTFSERANRSSLHAPFSPNSESLASAYHTNTRAHAYGDPNTGLNSQLHYKRQMYQQQQEEYKDWASSSAQGVIAAAQHRQEGPRKSPRQQQFLDRVRSPLKNDKDGMMYGPPVGTYHDPSTQEAGRCLMSSDGLPAKSMELKHSSQKLQESCWDLSRQTSPAKSSGPPGMSNQKRYGPPHEPDGHGLAESAQSSKPSNVMLRLPGQEDHSSQNPLIMRRRVRSFISPIPSKRQSQDVKNSNADDKGRLLHPSKEGADKAYNSYSHLSHSQDIKSIPKRDSSKDLPNPDNRNCPAVTLTSPAKTKILPPRKGRGLKLEAIVQKITSPNIRRSASANSAEAGGDTVTLDDILSLKSGPPEGGTVATQEAEMEKRKCEVVSDLVSVTNQESNVEKPLPGPSEEWRGSGDDKVKTEAHVETASTGKEPSGTMTSTASQKPGGNQGRPDGSLGGAAPLIFPDSKNVAPVGILAPEANPKAEEKENDTVMISPKQESFPPKGYFPSGKKKGRPIGSVNKQKKQQQQPPPPPQPPQMPEGSADGEPKPKKQRQRRERRKPGAQPRKRKTKQAVPIVEPQEPEIKLKYATQPLDKTDAKNKSFFPYIHVVNKCELGAVCTIINAEEEEQTKLVRSRKGQRSLTPPPSSTESKVLPASSFMLQGPVVTESSVMGHLVCCLCGKWASYRNMGDLFGPFYPQDYAATLPKNPPPKRSSEMQSKVKVRHKSASNGSKTDTEEEEEQQQQKEQRSLAAHPRFKRRHRSEDCGGGPRSLSRGLPCKKAATEGSSEKTVSDTKPSVPTTSEGGPELELQIPELPLDSNEFWVHEGCILWANGIYLVCGRLYGLQEALEIAREMKCSHCQEAGATLGCYNKGCSFRYHYPCAIDADCLLHEENFSVRCPKHKPPLPCPLPPLQNKTAKGSLSTEQSERG
What is the function of this protein?
Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression.  It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator.
What are the official names of this protein?
Transcription factor 20, TCF-20, Nuclear factor SPBP, Stromelysin-1 PDGF-responsive element-binding protein, SPRE-binding protein.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL18_METST
Sequence: MARGATYKVQFKRRREGKTNYNKRYKLVDLDKTRMVVRITSNHTITQLVKIGENGDETLVSATSKNLKEFGWLGNGKNTSAAYLTGYLFGKKALNEGYDETILDIGVQPSIKGTKIYAVLKGALDAGLYIPHNDSILPEDSRIRGEHIAQYAESMDDDEKNAKFANYIRCGLSPEEIPDHFESVKNKIDEATQ
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: FH11_ORYSJ
Sequence: MMRHCRREWLLALCLISVQLLIPTGCEGVLVAASNMSPPALTPLLINQVDQLVEHAWVKCGLDKRTLEDVRRHFNYNHVLAILRRMSGQDIKDTSPDIDGGTSVLSLERRDAILNCLSKQNFMSIAGQDGLKILSADYIKALIASLRTDLAQESSTTKSIPEQAGKPVPGKTSTPKPVNKPTDSVSSPPDRSYKSAPTEKENPPTKSVAEKKKDSSGMPNAFIGLSIAGIALMAHLCLCCFMCHGTSSSDLRDDKPLLTLNPSNLSAASKSSQGNPIDVNKLGVVSLKSEAGQNGDVKLISKEGTNNVNVVHPVSSVSESTLMPPPEGANNVNMVHPEGANNMNVVHPEGANNVNMVHPEGANNVNVNMVHPVGSLSESTPMQPPVMPPPIPKLLSPPAPQAPMPPLKASPVPPPEPSPPPAPKAAPPPPPPKSTGPGPPRPPPPAMPGSSKTRPPPPLKPGAKVGAVENSNEAKTKLKPFFWDKVTANPARSMVWDHLKSGSFQFNEQLMENLFGYNSTDKSSDTKKDLSSKDATQLIRILDPKKAQNLAISLRALGVSPQEVCSAVKEGSELPSDLIQTLIRWSPSNDEELRLRLYSGELFQLGPAEQFLRVIIDIPYIFQRLDALLFMANLPEEASNVKQSFATLEVACQELRNSRLFMKLLEAVLKTGNRMNVGTFRGGAQAFRLDTLLKLSDVKGTDGKTTLLHFVVQEIIRSEGVRAERAAKEQNSGVSSVKTDDLGDKSEQTEDGYKQLGLKVISSLGDELQDVRKAAILDADQLTMSVASLGHKLMKTNEFLNMDMKSLDEDSGFHRKLTHFVQQSQTDITFLLEEEKKMRLLVKDTVDYFHGSAGKDEGLRLFVIVRDFLAMLDKVCKEVKEASKVAPVKAKAKQPSQSLQSFRDPRVNLFPAIQHLRADSSSSSSDDES
What are the official names of this protein?
Formin-like protein 11, OsFH11.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SX17A_XENTR
Sequence: MSSPDGGYASDDQNQGKCSVPIMMTGLGQCQWAEPMNSLGEGKLKSDAGSANSRGKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKALTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRMKRADTGFMHMAEPPESAVLGTDGRMCLESFSLGYHEQTYPHSQLPQGSHYREPQAMAPHYDGYSLPTPESSPLDLAEADPVFFTSPPQDECQMMPYSYNASYTHQQNSGASMLVRQMPQAEQMGQGSPVQGMMGCQSSPQMYYGQMYLPGSARHHQLPQAGQNSPPPEAQQMGRADHIQQVDMLAEVDRTEFEQYLSYVAKSDLGMHYHGQESVVPTADNGPISSVLSDASTAVYYCNYPSA
What is the function of this protein?
Transcription activator.  Binds to the DNA sequence 5'-AACAAT-3'.  All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in function.  In addition, the sox17 proteins have distinct but overlapping roles in later gut development.  Acts downstream of vegt-signaling in endoderm differentiation to induce a range of endodermal genes both directly (including endodermin and dhh/chh) and indirectly.  Also represses wnt-responsive genes to inhibit wnt/beta-catenin signaling (By similarity).
What are the official names of this protein?
Transcription factor Sox-17-alpha, Sox17alpha, tSox17alpha.
What are the subcellular locations of this protein?
Nucleus.
Protein: RECA_BORAP
Sequence: MSKLKEKREKVAVSIERSSKEEAVELARVQIEKTFGKGSLIKMGESPVGKGIKSISSGSIVLDEALGIGGYPRGRIIEIFGPESSGKTTLTLQAIAEVQKEGGIAAFIDAEHALDPVYAKALGVNVAELWLSQPDTGEQALEIAEHLIRSGGIDLIVVDSVAALTPKLEIDGEMGDSQIGLQARLMSKALRKITGILSKSNTCIMFINQIRMRIGIMFGNPETTTGGNALKFYASLRLEVRKVEQITRSGSSDDVIGNKIRVKIVKNKVAPPFRKVELVIYFGKGISREAGILDAAIKHNLIQKTGSWYSLGDNKLGQGRESVIEYLSKEVELTNDLDKRLRKVIFNNFDQEDVSFIEYKENESE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SFSA_SALSV
Sequence: MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQSGAFICVNTLRANQLTKEAIQENRLPALAGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSAQKMELNEPVPITL
What is the function of this protein?
Binds to DNA non-specifically.  Could be a regulatory factor involved in maltose metabolism.
What are the official names of this protein?
Sugar fermentation stimulation protein A.
What is the protein family that this protein belongs to?
Belongs to the SfsA family.