PharMolix/UniProtQA huggingface dataset:
Protein: CYC_LITCT
Sequence: MGDVEKGKKIFVQKCAQCHTCEKGGKHKVGPNLYGLIGRKTGQAAGFSYTDANKNKGITWGEDTLMEYLENPKKYIPGTKMIFAGIKKKGERQDLIAYLKSACSK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: VIRA_SHISS
Sequence: MQTSNITNHERNDSSWMSTVKSTTEVSWNKLSFCDVLLKIITFGIYSPHETLAEKYSEKKLMDSFSPSLSQDKMDGEFAHANIDGISIRLCLNKGICSVFYLDGDKIQSTQLSSKEYNNLLSSLPPKQFNLGKVHTITAPVSGNFKTHKPAPEVIETAINCCTSIIPNDDYFPVKDTDFNSVWHDIYRDIRASNSNSTKIYFNNIEIPLKLIADLINELGINEFIDSKKELQMLSYNQVNKIINSNFPQQDLCFQTEKLLFTSLFQDPAFISALTSAFWQSLHITSSSVEHIYAQIMSENIENRLNFMPEQRVINNCGHIIKINAVVPKNDTAISASGGRAYEVSSSILPSHITCNGVGINKIETSYLVHAGTLPSSEGLRNAIPPESRQVSFAIISPDV
What is the function of this protein?
Alpha-tubulin-specific protease that is required for entry into epithelial cells and for subsequent intra- and intercellular spreading.  Contributes to bacterial entry into epithelial cells by inducing microtubule (MT) destabilization and the formation of membrane ruffles.  The membrane ruffling evoked by VirA results from the activation of host rac1, which is associated with the destruction of MT networks.  Creates a tunnel inside the host cell cytoplasm by breaking down the microtubule infrastructure.  This facilitates the bacterium's movement through the cytoplasm and also helps other bacteria move faster during the invasion of the eukaryotic cell.  Is absolutely required for virulence (By similarity).
What are the official names of this protein?
Cysteine protease-like VirA, Effector protein VirA.
What is the protein family that this protein belongs to?
Belongs to the protease EspG/VirA family.
What are the subcellular locations of this protein?
Secreted. Note=Translocated into the host cell via the type III secretion system (TTSS). Localizes in the cytoplasm of the infected cell (By similarity).
Protein: PURR_ECOLU
Sequence: MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
What is the function of this protein?
Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression.  PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
What are the official names of this protein?
HTH-type transcriptional repressor PurR, Pur regulon repressor, Purine nucleotide synthesis repressor.
Protein: PAT14_SOLTU
Sequence: MATTKSFLILFFMILATTSSTCAKLEEMVTVLSIDGGGIKGIIPAIILEFLEGQLQEVDNNKDARLADYFDVIGGTSTGGLLTAMITTPNENNRPFAAAKDIVPFYFEHGPHIFNYSGSIIGPMYDGKYLLQVLQEKLGETRVHQALTEVAISSFDIKTNKPVIFTKSNLAKSPELDAKMYDICYSTAAAPIYFPPHYFITHTSNGDIYEFNLVDGGVATVGDPALLSLSVATRLAQEDPAFSSIKSLDYKQMLLLSLGTGTNSEFDKTYTAQEAAKWGPLRWMLAIQQMTNAASSYMTDYYISTVFQARHSQNNYLRVQENALTGTTTEMDDASEANMELLVQVGETLLKKPVSKDSPETYEEALKRFAKLLSDRKKLRASKASY
What is the function of this protein?
Probable lipolytic acyl hydrolase (LAH), an activity which is thought to be involved in the response of tubers to pathogens.
What are the official names of this protein?
Patatin-14.
What is the protein family that this protein belongs to?
Belongs to the patatin family.
What are the subcellular locations of this protein?
Vacuole.
Protein: LPXA_SALPC
Sequence: MIDKSAFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVLKSHVVVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR
What is the function of this protein?
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, UDP-N-acetylglucosamine acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PER_DROER
Sequence: GGSGGSGSSGNFTTASNIHMSSVTNTSIAGTGGTGGTGTGTGTGTGTGTGTGTGTDTGTGTGTRNGTNSGTNSGTRTGTASSYRGGGGGAGGGGGVTIQHLTLTESLLNK
What is the function of this protein?
Essential for biological clock functions.  Determines the period length of circadian and ultradian rhythms; an increase in PER dosage leads to shortened circadian rhythms and a decrease leads to lengthened circadian rhythms.  Essential for the circadian rhythmicity of locomotor activity, eclosion behavior, and for the rhythmic component of the male courtship song that originates in the thoracic nervous system.  The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex.  Light induces the degradation of TIM, which promotes elimination of PER.  Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop.  Behaves as a negative element in circadian transcriptional loop.  Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).
What are the official names of this protein?
Period circadian protein.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, perinuclear region. Note=Nuclear at specific periods of the day. First accumulates in the perinuclear region about one hour before translocation into the nucleus. Interaction with Tim is required for nuclear localization (By similarity).
Protein: RSXA_ECOK1
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTMAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SCX3_ANDAM
Sequence: MNYLVMISLALLFMIGVESARDGYIAQPNNCVYHCIPLSPGCDKLCRENGATSGKCSFLAGSGLACWCVALPDNVPIKIIGQKCTR
What is the function of this protein?
Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission.
What are the official names of this protein?
Toxin Aam3, AamH3, Alpha-neurotoxin 3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Alpha subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: HSCA_ACTSZ
Sequence: MALLQIAEPGQSAAPHQHKLAIGIDLGTTNSLVATVRNGQAEILLDEKERPLTPSIVHYGDNVTVGYDAGELASRDPQNTIISVKRLIGRSLNDVQARYPNLPYRFVRSENGLPLLGTAQGNVSPIEVSGEILKKLTALAQHRLNGELLGVVITVPAYFDDAQRQSTKDAAKLAGLNVLRLLNEPTAAAIAYGLDSGREGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDTALGGDDFDHLIADWISEKSGIQPQDDQQKRLLIELAARTKIALTDKPQVSLSYQGWQGEMQREEFNGLISGLVKRSLMACRRALKDAGIGQSEVQEVVMVGGSTRVPFVRDQVGEFFQRRPLTSIDPDKVVALGAAIQADILVGNKPDNEMLLLDVIPLSLGIETMGGLVEKIIPRNTTIPVARAQEFTTFKDGQTAMSVHVVQGERELVGDCRSLARFTLRGIPPMAAGAAHIRVTYQVDADGLLSVTAMEKSTGVQSSIQVKPSYGLTDDEITQMLKASMENAKEDIGARMLAEQRVEARRVIEAVLSALLDDQDLLNDEELSTVKNALVSLDNLQQGTDTQAIKAGIKALDAATQEFAARRMDKSIRRALSGQSVDSL
What is the function of this protein?
Chaperone involved in the maturation of iron-sulfur cluster-containing proteins.  Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
What are the official names of this protein?
Chaperone protein HscA homolog.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RS17_VEREI
Sequence: MTEAQKSLKRTLIGKVVSDKRQKTVTVLVERRVKHELYGKIIARSSKYHAHDEKGEYKLGDMIEITESRPLSKTKNWVASRLVQKAGLL
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: SELO_XANC5
Sequence: MTHLHFDNRLRQQLPGDPEEGARRREVGAAWSSVLPTPVAAPYLIAHSAEMAQVLGLEAAEIASAQFAQVFGGNALYPGMQPWAVNYGGHQFGHWAGQLGDGRAISLGEAIGTDGGRYELQLKGAGPTPYSRGADGRAVLRSSIREFLCSEAMHHLGVPTTRALSLVGTGEAVVRDMFYDGHPQREPGAIVCRVAPSFIRFGNFELPSARGDIALLKQWVDFTIARDFPALAGAGEALYADWFAQVCERTAVMVAHWMRVGFVHGVMNTDNMSILGLTIDYGPYGWVDDYDPDWTPNTTDAQGRRYRFGTQPQVAYWNLGRLAQALAPLFADQALLQYGLDRFRDTYLACDRRDTAAKLGLAECRDEDLQLIDALRALMRESEMDMTLTFRGLIDLSPEHPDPAQLRDAFYDEDKRLVDAPQLQQWLQRYAARLQQDPLSPEERRARMRLANPRYVLRNYLAQQAIDRAEQGDPSGVQELLEVMRRPYDDQHGRDAFAARRPDWARDRAGCSMLSCSS
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: ISCR_CROS8
Sequence: MRLTSKGRYAVTAMLDVALNSESGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDAGQIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSDRQHNEAHRPTRAQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: VME1_IBVBC
Sequence: MPNETNCTLDFEQSVQLFKEYNLFITAFLLFLTIILQYGYATRSKVIYTLKMIVLWCFWPLNIAVGVISCTYPPNTGGLVAAIILTVFACLSFVGYWIQSIRLFKRCRSWWSFNPESNAVGSILLTNGQQCNFAIESVPMVLSPIIKNGVLYCEGQWLAKCEPDHLPKDIFVCTPDRRNIYRMVQKYTGDQSGNKKRFATFVYAKQSVDTGELESVATGGSSLYT
What is the function of this protein?
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
What are the official names of this protein?
Membrane protein, M protein, E1 glycoprotein, Matrix glycoprotein, Membrane glycoprotein.
What is the protein family that this protein belongs to?
Belongs to the gammacoronaviruses M protein family.
What are the subcellular locations of this protein?
Virion membrane; Multi-pass membrane protein. Host Golgi apparatus membrane; Multi-pass membrane protein. Note=Largely embedded in the lipid bilayer.
Protein: HSLU_PSET1
Sequence: MSAMTPREIVHELDQHIIGQAKAKKAVAIALRNRWRRMQLSDDLRNEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEIGYVGKEVETIIRDLVDVAIKMTREQQTKKFKHRAEEAAEERILDALLPPAKDQYGESQRDDSSSTRQTFRKKLREGQLDDKEIEIDLAQAQPNVEIMAPPGMEDMTNQLQSMFQNMGGDKRTKRKLKIKEAFKLLSEEEAAKLVNPEELKEQAIFAVEQNGIVFIDEIDKICKRGDSSGPDVSREGVQRDLLPLIEGCTVSTKHGMVKTDHMLFIASGAFQMAKPSDMIPELQGRLPIRVELEALTADDFKRILTEPHASLTEQQRELLKTEQVTIEFSDDAIERIAKAAWQVNEKTENIGARRLHTVMEKLMEEISYDASEQAGTSLVVDAAYVEKHLGALVEDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPC_RHOCB
Sequence: MTNILDRIKAYKLEEVAAAKARVSFADLEAQARAQAPCRGFAEALRKKSAQGYGLIAEIKKASPSKGLIRPDFDPPALARAYEDGGAACLSVLTDTPSFQGAPDYLIAARNACALPALRKDFLYDPYQVAEARAWGADCILIIMASVEDALAVELEAAATGWGMDVLIEVHDGAELDRALKWLKSPLLGVNNRNLKTFEVTLDVTRQLAPVILAEGRELVCESGIFTPADMAAMAAVGARRFLIGESLMRQADVAAATRALLAC
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: RSMA_VIBC3
Sequence: MRNDVHLGHKARKRFGQNFLNDPYIIDGIVSAINPKPGQNLVEIGPGLGAITEPVGREVDKFTVIELDRDLAERLRNHPELASKLTIHEGDAMRFDFKQLVKPNNKLRVFGNLPYNISTPLMFHLFEFHRDIQDMHFMLQKEVVNRLAAGPGTKAYGRLTVMAQYYCKVVPVLEVPPSAFVPPPKVDSAVVRLVPYEDLPHPATSLEWLDRVVREGFNQRRKTVRNCYKGLAEPETLETLGINPGMRPENLTLAQFVALANWLDATHKTHA
What is the function of this protein?
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase A, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SECA_FRAP2
Sequence: MLNLVQKIIGSRNDRFIKKVSKTVQKINSLEPEFEKLSDQELKAKTQEYKDRVAKGEALDNLLPEAFATVREAGKRTKNMRHYDVQLIGGIVLHQGKVAEMRTGEGKTLVATLPAYLNALTGNGVHVITVNDYLAKRDAELMSDIYEFLGLSVGVIVADLNPEQRRESYACDITYGTNNEFGFDYLRDNMAYDKEQQVQRSRNYVIIDEVDSILIDEARTPLIISGASDDSSEMYNLFNRLVPFLEKQEKEELDEDQEQKDFYVDEKSKNAYLTEKGYAKIESMLKKEGILEEDDNLYSPHNITKMHYLNACLRAHSLYQLNIDYIVRDQEIVIIDESTGRAMPGRRWSDGLHQAIEAKEGVKINAENQTMASITFQNFFKLYNKIAGMTGTADTEAFELHSIYGLEVIIIPTNKPLIRKDHHDEIYGSVREKFDAIVEDIKQRISKGQPVLVGTASIEASEVLSTLLKKKKIRHNVLNAKQHEKEASIIAMAGYPGNVTIATNMAGRGTDIILGGNLEVEIAQLEDPTPEEVAQIKAEWVKRNEVVKNAGGLCIIGSERHDSRRIDNQLRGRAARQGDPGESKFYLSMDDNLLRIFASQSMAERVKKGLKGGESLAFGFMSKVISKAQGKVESYHFDIRKNLLEYDNVVNTQRKVIYEQRQAFLDSDDVSEILADIRIDVAEQLFHDYVPAGSMHELWDLEGLEKALKSDFMIEIDLQKLYEEDDNLGEEDLKKFVREAIEFEFAEKTKNLEVGAVRQFEKFSLLQSLDSHWREHLSSIDHLRNSINLRGYAQKDPKNEYKKEAFELFSTMLDNFKYEVISSLAKIRIATEEETQRAQEEWKESMSEIKAEHESVIDNNQSEDDKEQEEAPKVQQVKREGPKIKRNDPCPCGSGKKYKQCHGKVVD
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: AIM11_YEAS2
Sequence: MIEEKKELKKRRVLQMARFYGAAAFTLITMRLISRAIKVRKCNVPSIFQQNYKLPPFSQRNEAMSALTYASAASIGTFSTLIFGFCWALDISTAREFVFKTREFMSLPQALETDTSMDEETSKLTKQLQDLLSSENNK
What are the official names of this protein?
Altered inheritance of mitochondria protein 11, Genetic interactor of prohibitins 8.
What is the protein family that this protein belongs to?
Belongs to the AIM11 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DEF1_CANTT
Sequence: MSTFRKSYKNQSKRFNNSHSNSSSTSVELTNLVEMFPDWEADELQGLLSENDNSLEIVIDLIVNNKVSKWEPIKKEKHKKKEKETEDHNSSTNGSTNSASTSSTAPSSDRKPYNKSKPQSSSTRPPKKQHANANYKKGGEKSAEKPKPTSTTSSTTTTPVQKETTPATNSWAAALSNDKPKKSVATTEESEPVEHAEEDGAKAQQEEQETVAELDNTTTTNGEQQEQQPEEETTQESQAPVEQAKPVLKEAAIPEPKQGSWASAITPKTVKPKAKPAPKPVSQPQPPKEEEEKEEKEPVVEEQVSEPVESIAEETVAEVSQSIPSEEPIESPVATATTTTAATTTEPSIVEQPQQQQQPQVVLPTSQQQVNSVGISFGSLSIQEESKDAEVPREEVIAEQTSQPEQTQQQQQQPIQDQQRYGLYNQQQTQQRYQQQQQSAYQQQPQQQQQQNQYSKQQQQQQQAPIQQQTAQQQYDYYNQFQQQYPQQTAQPGAQFGGYPGFDYSGYNQQAFAAASPAANHIATLGGSAGVGGGYGQYAQQAGSTDSSHSPITNQSTLQQQQAAAAALNAQQQQQQMPTPFGYPAYYNYYYNNPYFNAGGLGSTGFGAPQQGNQQGQQPTSSQGASQQGQAQPQVPSAGSQQGGASMGSNGFGGQQQYYNPNQFNNRYPGYSYPPQQQQQQQQPVQQNAGQSQQGSSQSASNSEGASDGQQSSSQGQQGQQGQGPQGVQQGQGQQPPVPQQHMMPQYGGYQQYPQYGYQDSNQYRGGWY
What is the function of this protein?
Recruits the ubiquitination machinery to RNA polymerase II for polyubiquitination, removal and degradation, when the transcription-coupled repair (TCR) factor RAD26 fails to efficiently displace stalled RNA polymerase II.  Also involved in telomere length regulation.  Binds DNA.
What are the official names of this protein?
RNA polymerase II degradation factor 1.
What is the protein family that this protein belongs to?
Belongs to the DEF1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: GPHR_CRIGR
Sequence: MSFLIDSSIMVTSQILFFGFGWLFFMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSSSRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIQLLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERRLLQTMDMIISKKKRMAVARRTMFQRGEVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVSSIRGLLITLTKFFYAISSSKSSNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITQVLGELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP
What is the function of this protein?
Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance (PubMed:18794847).  Plays a role in lymphocyte development, probably by acting as a RABL3 effector in hematopoietic cells (By similarity).
What are the official names of this protein?
Golgi pH regulator, Protein GPR89.
What is the protein family that this protein belongs to?
Belongs to the Golgi pH regulator (TC 1.A.38) family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Multi-pass membrane protein.
Protein: XYLA_RUEST
Sequence: MTTGFFGDVSKITFEGADSTNPLAFRHYNPDEVILGKRMEEHLRFATCYWHNFVWPGGDPFGGQTFDRPWFKDTMHAAKLKADVAFEMFTLLQSPYYCFHDADVRPEGANFAENTRNLNEIVDYFAQKQEETGVKLLWGTANLFSNARYMSGASTNPDPDVFAFSAATIKTCMDATHRLGGENYVLWGGREGYETLLNTDLAQEDQQMGRMLNMVVEYKHKIGFKGAILVEPKPQEPSKHQYDYDAATVYGFLKRHGLENEVKLNLEQGHAILAGHSFEHEIATAQALGIFGSIDMNRNDYQSGWDTDQFPNNTPEVALAYYHILKHGGFTTGGTNFDAKLRRQSIDAEDLLMAHIGGMDICARGFKAAAAMIEDGTLDQFVTDRYAGWQTDPAQDMLAGKLSLDEIAKRVEAEDINPKPRSGRQEYLENLINRFV
What are the official names of this protein?
Xylose isomerase.
What is the protein family that this protein belongs to?
Belongs to the xylose isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLPD1_MYCTU
Sequence: MLMPHSAALNAARRSADLTALADGGALDVIVIGGGITGVGIALDAATRGLTVALVEKHDLAFGTSRWSSKLVHGGLRYLASGNVGIARRSAVERGILMTRNAPHLVHAMPQLVPLLPSMGHTKRALVRAGFLAGDALRVLAGTPAATLPRSRRIPASRVVEIAPTVRRDGLDGGLLAYDGQLIDDARLVMAVARTAAQHGARILTYVGASNVTGTSVELTDRRTRQSFALSARAVINAAGVWAGEIDPSLRLRPSRGTHLVFDAKSFANPTAALTIPIPGELNRFVFAMPEQLGRIYLGLTDEDAPGPIPDVPQPSSEEITFLLDTVNTALGTAVGTKDVIGAYAGLRPLIDTGGAGVQGRTADVSRDHAVFESPSGVISVVGGKLTEYRYMAEDVLNRAITLRHLRAAKCRTRNLPLIGAPANPGPAPGSGAGLPESLVARYGAEAANVAAAATCERPTEPVADGIDVTRAEFEYAVTHEGALDVDDILDRRTRIGLVPRDRERVVAVAKEFLSR
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase 1.
What is the protein family that this protein belongs to?
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TATA_BURO0
Sequence: MGGLSIWHWLIVLLIVALVFGTKKLRNIGNDLGSAVKGFKDGMKEGETPADAQQLPRSGAVDVNAKETTRSDSNKA
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
Protein: HCAF_ECOLC
Sequence: MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTMRTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNCQVSETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQAVITSHNLSVLF
What is the function of this protein?
Part of the multicomponent 3-phenylpropionate dioxygenase.  Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol), respectively.
What are the official names of this protein?
3-phenylpropionate/cinnamic acid dioxygenase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.
Protein: G3P_STREQ
Sequence: MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGNFIKVSAERDPENIDWATDGVEIVLEATGFFAKKEAAEKPLHANGAKKVVITAPGGNDVKQLFSTLTTSILDGTETVISGASCTTNCLAPMAKALHDAFGIQKGLMTTIHAYTGDQMIVDGHRGGGDLRRARAGAANIVPNSTGARKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVVTLDKNVSVDEINAAMKAASNDSFGYTEDPIVSSDIVGVSYGSLFDATQTKVMEVDGSQLVKVVSWYDNEMSYTAQLVRTLEYFAKIAK
What is the function of this protein?
Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD.  The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH.  The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.
What are the official names of this protein?
Glyceraldehyde-3-phosphate dehydrogenase, GAPDH, NAD-dependent glyceraldehyde-3-phosphate dehydrogenase, Plasmin receptor, Plasminogen-binding protein.
What is the protein family that this protein belongs to?
Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CADF2_PLAF7
Sequence: MVSGVKVSDECVYEFNKLKIKHIHKYIIYRIENYEEVIVDFLEQDNSLKSYKDIIIDIRNNLKTTECRYIIADMPIPTPEGVLRNRIYFIFWSPDLAKSKEKMLYASSKEYLVRKINGIFKSLEITCDLEDFEDELRTIILNT
What is the function of this protein?
Not involved in actin polymerisation, instead functions to stimulate nucleotide exchange on monomeric actin and influence turnover of the small amount of cytosolic actin microfilaments.  Essential for erythrocytic schizogony (By similarity).
What are the official names of this protein?
Cofilin/actin-depolymerizing factor homolog 2.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton.