PharMolix/UniProtQA huggingface dataset:
Protein: GPN3_GIBZE
Sequence: MSKFGAMVMGPAGAGKSTFCAALITHLNLNRRSAFYINLDPAAESFEHEPDLDIKELISLKDAMEEVGLGPNGGLIYCFEFLMENLDWLTDALEGLTEEYLIIIDMPGQIELYTHVPILPALVKFLSQPGSLDVRMAAVYLLEATFVVDRAKFFSGTLSAMSAMLMLEVPHINILSKMDLVKGQVKKKDLKRFLTPDVGLLDDDPVEHTRRIAEGQDAEDDESKAPDEKDQVMKGASFRRLNRAVAGLIESFSMINYHKLDVTNEDSVAAILSYIDDCIQFHEAQDPKEPHDDEETEEFEG
What is the function of this protein?
Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII).  May act at an RNAP assembly step prior to nuclear import.
What are the official names of this protein?
GPN-loop GTPase 3.
What is the protein family that this protein belongs to?
Belongs to the GPN-loop GTPase family.
Protein: ACCD_BEII9
Sequence: MNWISNVVPPKIRSFLRRDTPENLWIKCPESGELVFHKDLEANLFVIPGSGYHMYIAPKPRLDALFDEGVYETIPTPEVPLDPLKFRDVKRYTDRIKEYRQKTGAPDAVKLAYGKLQGLDAVVAVQDFAFLGGSLGMAAGEAVITGMQQALERQAPFIIFTASGGARMQEGMFSLMQMPRTTLMVQALREARLPYIVVLTHPTTGGVSASYAMLGDIQVAEPGAVIGFAGARVIEQTIHEHLPEGFQRAEYLQAHGMVDMVVRRHDLPAVLARLCAFLTNSPRRAPIPA
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_CHLSY
Sequence: MEELIAIVGPTAVGKTELAVAWARRINGEIVSADSRQIYRWMDIGTAKPSPEEQAQAPHHLIDIRDPDQPFSLAEFCDLATAAIADIRGRGRIPLLVGGTGQYLAAFLEGWQVPRVAPQPDLRAELELIAAREGPAVLHARLAAVDPVAASRIPPTNVRRVVRALEVYLVSGEPISRLQERKEPPFRPRTIWLHRPRAELYARADARIERMIAAGLVEEVAGLLARGYDWSLPAMSSLGYIQFRPYFTGEADLPTCIERLRFDTHAFIRRQEMWFRRLPNLEIWTPDHPSWREITA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: NUOL_BUCBP
Sequence: MNFVYLVVLCPLVSFCLLLFFIDYLPKMLVKKIGIVSIFISMIITFYSLFDFLNCGKQCVFYIPLWVWISIDYLKIDFNFMLDGLSITMLTMTTSIGFLIHLFSSWYIKLQDEYTRFFSYMNLFIASMVLLLLADNLLVMYIGWEGVGLCSYLLVGFYYSKINSGYAAIKGFIITRIGDIFLILAIFFIYKNFGTLNFRELKLIFETTNVVENFKFLNYVSLFLLIAAIAKSAQVPLQTWLIDAMAGPTPASALIHSSTMVTAGVYLIARMNFLFSLSPIILYILGIISCLTIIMSCLSALVQKNIKCILAYSTMGQVGYMFLALAMKEWTLAINHLVTHAIFKTLLFLSAGAVIILLNNEKNIFNMGGLRKKFPMLYFSFLIGGASLASFPILTSGFYSKGNILFSALENNYYLFLVLGLLGSVLTSIYTFRMIFLVFCGAQKYRAHYVFFSRTLANTLPLLILILLSTVIFVLIHLPLSSVFSKTTPSFLINNNKLLFEIGCSVLSLLGMFISYYLFLVNRMLVDLLLNTKLGNFIYNFWYDSWGFNSLYNILCVNPYLYVAKRLKHDPINIFMSIPITFCFFVSKNLKYIHNGYLRVYVFSIMFGLFLFILMAIRLYK
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit L, NADH dehydrogenase I subunit L, NDH-1 subunit L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 5 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: IF2_ACTP7
Sequence: MSDNEIKNEAPKKLSLQRRTKTTVADGKVQVEVRKSRKIDTAAVKKAQEEAALKAKQEAEAKAQAEKTAAEQAKAEAEAAKKAEGAKVEATKKSAPAVPVMPNSKPKAAAPKAEQPKQEKALDPEKEAKKKEEAELRRKQEELARQKAEMEAKRAAENARRLAEIAREEAAENGEEFEDDRFTSSYAREADRDNDRRSEANRGRGKGGVNKAKKGDREDKNERNADRRNQKDVKGKGKNAKKGSALQQAFTKPVQVNKADVVIGETITVAELANKMAVKATEIIKTMMKMGEMVTINQVIDQETAQLVAEEMGHKVILRNENELEDAVMEDRDVDAEKVTRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVETEDGKMITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTIEAIQHARAAGAPIVVAVNKIDKPEANPDRVEQELLQHEVVSEKFGGDVQFVPVSAKKGLGIDDLLEAILLQSEVLELTAVKEGMASGVVIESYLDKGRGPVATILVQSGTLNKGDIVLCGFEYGRVRAMRDENGKEVDSAGPSIPVEVLGLSGVPAAGDEATVVRDEKKAREVALFRQGKFREVKLARQQKAKLENMFSNMTAGDVAELNVIVKADVQGSVEAICQSLAELSTDEVKVKVVGSGVGGITETDATLAAASNAIMVGFNVRADASARRVIEAENIDLRYYSIIYELLNEIKAAMSGMLQPEFKQEIIGLAEVRDVFRHPKFGAIAGCMVTEGVVKRNNPIRVLRDNVVIFEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVKVGDQIEVFEVVEVKRSI
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YNBA_ECOLI
Sequence: MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLLTGLLLMLAAQPILFLLLPIVLFIRMALNALDGMLARECNQQTRLGAILNETGDVISDIALYLPFLFLPESNASLVILMLFCTILTEFCGLLAQTINGVRSYAGPFGKSDRALIFGLWGLAVAIYPQWMQWNNLLWSIASILLLWTAINRCRSVLLMSAEI
What are the official names of this protein?
Inner membrane protein YnbA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YABA_BACC4
Sequence: MEKKDIFESVSSMEEQIGHLYKQLGELKQHLAELLEENQHIKMENNNLRHRFEEVQNKEKQKTQKRKEVKPKTDIGEGYDNLARLYQEGFHICNLHYGSVRKEGDCLFCLSFLNKK
What is the function of this protein?
Involved in initiation control of chromosome replication.
What are the official names of this protein?
Initiation-control protein YabA.
What is the protein family that this protein belongs to?
Belongs to the YabA family.
Protein: TSR1_PONAB
Sequence: MAAHRPGTLKQQNKAHKGGRHRGRGSAQRDGKGRLALKTLSKKVRKELSRVDQRHRASQLRKQKKEAVLAEKRQLGGKDGPPHQVLVVPLHSRISLPEAMQLLQDRDTGTVHLNELGNTQSFMLLCPRLKHRWFFTSARPGDLHIVLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGISGLPLKKQIDARKKLSKAVEKRFPHDKLLLLDTQQEAGMLLRQLANQKQQHLAFRDRRAYLFARAVDFVASEENNLVGTLKISGYVRGQTLNVNRLLHIVGHGDFQMKQIDAPGDPFPLNPRGIKPQKDPDMAMEICATDTVDDMEEGLKVLMKADPDRQESLQAEVIPDPMEGEQTWPTEEELSEAKDFLKESSKVVKKVPKGTSSYQAEWILDGGSQSGGEGDEYEYDDMEHEDFMEEESQDESSEEEEEEYETMTIGESVHDDLYDKKIDEEAEAKMLEKYKQERLEEMFPDEVDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPQDYARIFQFQNFTNTRKSIFKEVEEKEVEGAEVGCYVTLHVSEVPVSVVECFRQGTPLIAFSLLPHEQKMSVLNMVVRRDPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKLQRFLTADMALVATVYAPITFPPASVLLFKQKSNGMHSLIATGHLMSVDPDRMVIKRVVLSGHPLKMFTKMAVVRYMFFNREDVLWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFNGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWLKSEISSTVPQGGME
What is the function of this protein?
Required during maturation of the 40S ribosomal subunit in the nucleolus.
What are the official names of this protein?
Pre-rRNA-processing protein TSR1 homolog.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: RL3_KOSOT
Sequence: MKGIIGRKLGMTTIYEDGKALGVTVIKAGPCTVVQKKTAAGGEYNAIQLGFEELSPERAKKLLTKPILKKFEAAKVKPHRILKEIRVENPDEYNVGDVIDAGIFKEGELVDVTGWTKGRGFTGAMKRWNFGGGEVTHGSKFHRELGSVGNHTEPAKIWKGKKMPGRYGNERVTVLNVKVVKVDAENGLIAIHGAVPGARGGLVIIRAAKRPRK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: RNZ_PHOV8
Sequence: MEKFEVHILGCGSALPTTRHFATSQVVNIREKLFMIDCGEGAQMQLRKSKLKFTRLNHIFISHLHGDHCFGLMGLISTFGMLGRTATLYIHCHAELERLLTPQLDFFCKGMSYKVVFQTFDPGKAEIIYDDRSLTIETIPLRHRIPTCGFLFSEKQIPAHIRRDMIDFYEIPVYELNRIKNGADYTLPDGKIVPNNKLTIPSALPRRYAYCSDTIYLPHIIEQIYGVDLLFHEATFAQSEQARAKETFHTTASQAGEIARTAKVKQLLIGHFSARYEDESILLQEASDIFPNTLLARETLKISIESIKP
What is the function of this protein?
Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity.  Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.
What are the official names of this protein?
Ribonuclease Z, RNase Z, tRNA 3 endonuclease, tRNase Z.
What is the protein family that this protein belongs to?
Belongs to the RNase Z family.
Protein: SYH_CHLTE
Sequence: MTQFQGVKGTRDIFPDEISRWHYVEGVVHSVAALYGFSEIRTPVFEYTELFQRGIGATTDIVGKEMFTFLPDPNGRSLTLRPEMTAGVMRACLQKNLLSQAPVHKLWYISDLFRKERPQAGRQRQFTQFGAELLGVSNPAAVAEVLTLMMQVFETLGLHGLRLRINSLGDLDDRARYREALRAYFQPYEADLDELSKERLKKNPLRILDSKNPALQEMIMGAPRLYHSLKPESVAEFEQVLAYLDDRQIAYNVDHLLVRGLDYYCHTAFEVTSSELGAQDAIGGGGRYDGLARELGASADLPAVGFAVGMERLMIVMEKQGLFATLNPHGPLVSVIIQQKELAGHAMQVAFHLRKAGIKTEIDLAERSMKAQMRDANRMGSAYALFVGQSEFESGIYALKNLVTSEQTSLDLDAIIEVLREPAARESLRP
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBP16_EMENI
Sequence: MQEKPTTVAAYAAGASLAAVALFYVFGPNYTIDGDEAGGNRKKSIVGLSNPANDCFINSVLQALAGLGDLRLYLIRELHRRELDGPEIYNQLPGPEEADQLREKRPDRIRELQQGTITRALKEMLDRLNERPIYKKTISARAFIQALEFAYRTRISRNQQDAQEFLQIVAERLSDEYHAGVKARQRAEKSIEFNPYQEREEAPSEIEVRLDDGTENGLPAIIDTKLKEIDNEYGFPFEGKLESQIECQFCHYKYKPNQTSFVNLTLQVPQRSSTTLNACFDGLLKTEYIDDFRCDKCRLLHAIEVKSNALVKAGSATDRQRLEAEIEKIQLALSSDPENALDGVTLPPAELAPKRRIARHMRITVFPKIIAIHLSRSMFDRSGSTKNAAKVAFPERLPLGGILSQKWFKLLAIVCHKGSHNSGHYESFRRNHLYPPYSTPSVFSSYAQSRAASENPSRVASPRLPASSSSTEPPALNISPPASTSTNSPLSLTPDSPSRPPSATDLKSPRPTTSSSRVSFQSTHSSSKQTISPTSAARNSSSLDTARLSSPASRSSLAERNASATDTEASASASLASRIRRRRKTADRWWRISDEKIKECKTSDVLGMQKEVYLLFYEIEKSGS
What are the official names of this protein?
Ubiquitin carboxyl-terminal hydrolase 16, Deubiquitinating enzyme 16, Ubiquitin thioesterase 16, Ubiquitin-specific-processing protease 16.
What is the protein family that this protein belongs to?
Belongs to the peptidase C19 family.
Protein: LPXD_BRUMB
Sequence: MADPIFFKPSRELTIGDVADFTGASLRDPKLAPRSVERLASLKDAGEGALVFVEGKKNVSSLVGLKAAGVLCTESLADSVPSGIAVLVSRHPHRDFSAVGRMLFPASVRPESWLGETGISPAAFIHPTAQIEDGATVEAGAVIGSGVTIGAGTLIAATAVIGQNCQIGRNSYIAPGVSVQCAFIGNNVSLHPGVRIGQDGFGYVPGAAGLDKVPQLGRVIIQDNVEIGANTTVDRGSLDDTVIGEGTKIDNLVQIAHNVRIGRFCLVAAHCGISGSCVIGDQTMLGGRVGLADHLIIGSRVQVAAASGVMNDIPDGERWGGIPARPIKQWFRDIANIRSIGQSRKDASSDE
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: RS14Z_SPICI
Sequence: MAKKSLKVKQQCHPKFKVRGYTRCGNCGRPHAVLHKFDLCRLCFRNLASKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: H2A1N_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-N.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ENO_UREPA
Sequence: MKIINLLAYQILDSRGQPTVAVKLFLENDQSVIAMVPSGASTGAKEALELRDGDVNYFFNKSVKLAIQNINNIIRPHLINKNVLNFFELDNLLINLDGTENKSKLGANALLGVSIAIVKAGAIAASKPLYQYIKEDLMHNYDVNYYAPIPLMNFINGGAHADNDLDIQEFMIVPLNAISFSQAIQIGSEIFHQLDKLLKSNHLSTTKGDEGGFAPMLKNNYVTLELLVHAIKKAHYLPSKTQGVCLALDVAASELYENGKYFFKKSSSHNITLEQTSFSSDEWIKYWSKLVSMFPIISIEDCFEENDWNSFALFLKNNPHIQVVGDDLYCTNLKYLQKGIDFKATNAILIKPNQIGTISETLDVIKFAQKNNINTIISHRSGETEDTFIADLAIGVGAGQIKTGSLSRSERIAKYNRILEIEQELKDKLIYEPSKFFKFR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RECF_CHLTA
Sequence: MRVLSLFLKDFRNYTDLRLELGPEMNSIFGLNAQGKTNLLEALYILSLGRSFRTSRLTDAIRFGASHFFIEAVFSHKEVFHTLSIQVDKKGKKILFDGAPITKLSELVGLFPVILFSIKDIAIIEGSPSERRRFLDLLLAQASDKYTEHISLYHKALDQRNASIKAQNQKAISAWNSPLIAYGSLVAFLRNECTKKLNTIFQTLWDNTLKETLSLRYESSLITEESPTLNDIASNYYEQLRIANTKDLDLGYTMVGPHRDELLLTINDLPVAKFSSEGQKHSLLAVLRFAECVYLQEEFCIHPILCMDDIHACLDQQRLDQLLQLSNSLGQVVTTSTICPDHRSTTSCIFHVTQAQVSLVAPQSL
What is the function of this protein?
The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility.  RecF binds preferentially to single-stranded, linear DNA.  It also seems to bind ATP.
What are the official names of this protein?
DNA replication and repair protein RecF.
What is the protein family that this protein belongs to?
Belongs to the RecF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOH_ECO8A
Sequence: MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFLGLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.  This subunit may bind ubiquinone.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit H, NADH dehydrogenase I subunit H, NDH-1 subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 1 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MINC_CUPMC
Sequence: MSQKKSPRFELRSGNVDALLLALNTADLDAVRDDLLSRFESTPDFFSDDVVALDLRRLEGTGALALDRVIDTLATLKARAIGVVARADQRDWAGGFGLPLLDSQSRRGGKDEAPKEKAGKPEATAASGQTDAEAAGNTGKGKDSEGAAVNGKASEIAEIMAAANAASAPRAIPTLLIDKPLRSGQQIYAQGDVVILDLVSYGAEVIAEGNIHIYAPLRGRALAGVKGNPDARIFCTCLEPELISIAGIYRTAEQTLPADVLGKSAQVRLADEKLILEPLRMK
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: RL7A_AERPE
Sequence: MSKPIYVRFEVPEDLAEKAYEAVKRARETGRIKKGTNETTKAVERGLAKLVVIAEDVDPPEIVMHLPLLCDEKKIPYVYVPSKKRLGEAAGIEVAAASVAIIEPGDAETLVREIVEKVKELRAKAGV
What is the function of this protein?
Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
What are the official names of this protein?
50S ribosomal protein L7Ae, Ribosomal protein L8e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL8 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y035_BRUSI
Sequence: MRDMMGMMKQAKELQAKMKAMQDEIATMEASASSGGGLVTVTLSGKGTLSALKIDPSLMKEDEVEILEDLIIAAHNDAKAKLEAAMAEKTQSLTAGLPIPPGFKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein BSUIS_A0035.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RAE1E_ARATH
Sequence: MAVAPARARSDYDYLIKLLLIGDSGVGKSCLLLRFSDDTFTTSFITTIGIDFKIRTVELDGKRIKLQIWDTAGQERFRTITTAYYRGAMGILLVYDVTDESSFNNIRNWMKNIEQHASDSVNKILVGNKADMDESKRAVPTSKGQALADEYGIKFFETSAKTNQNVEQVFLSIAKDIKQRLTESDTKAEPQGIKITKQDANKASSSSTNEKSACCSYV
What is the function of this protein?
Involved in membrane trafficking from the Golgi to the plasma membrane.
What are the official names of this protein?
Ras-related protein RABE1e, AtRABE1e, Ras-related protein Rab8E, AtRab8E.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Golgi apparatus membrane. Cell membrane; Lipid-anchor.
Protein: RCNA_CITK8
Sequence: MGEFSTLLQQGNAWFFIPSAILLGVLHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAATLSHTAVVWLIALGGMYVSRAFTAESVEPWLQLVSAIIILSTAFWMFWRTWKGERDGLANRLPAHTHHHHDHEHHHHDHDHDHHHDHQHVHISLKGLTDGSHAWQDAHERAHATDIQRRFHDREVTNGQILLFGLTGGLIPCPAAITVLLICIQLKAFTLGATMVLCFSIGLALTLVAVGVGAAISVQQAAKRWSGFNTLARKAPYFSSILIGLVGLYMGMHGYLGIIR
What is the function of this protein?
Efflux system for nickel and cobalt.
What are the official names of this protein?
Nickel/cobalt efflux system RcnA.
What is the protein family that this protein belongs to?
Belongs to the NiCoT transporter (TC 2.A.52) family. RcnA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IL9_HUMAN
Sequence: MLLAMVLTSALLLCSVAGQGCPTLAGILDINFLINKMQEDPASKCHCSANVTSCLCLGIPSDNCTRPCFSERLSQMTNTTMQTRYPLIFSRVKKSVEVLKNNKCPYFSCEQPCNQTTAGNALTFLKSLLEIFQKEKMRGMRGKI
What is the function of this protein?
Multifunctional cytokine secreted mainly by T-helper 2 lymphocytes and also mast cells or NKT cells that plays important roles in the immune response against parasites (PubMed:29742432).  Affects intestinal epithelial permeability and adaptive immunity (PubMed:29742432).  In addition, induces the differentiation of specific T-cell subsets such as IL-17 producing helper T-cells (TH17) and also proliferation and differentiation of mast cells.  Mechanistically, exerts its biological effects through a receptor composed of IL9R subunit and a signal transducing subunit IL2RG.  Receptor stimulation results in the rapid activation of JAK1 and JAK3 kinase activities leading to STAT1, STAT3 and STAT5-mediated transcriptional programs.  Induction of differentiation genes seems to be mediated by STAT1 alone, while protection of cells from apoptosis depends on STAT3 and STAT5.
What are the official names of this protein?
Interleukin-9, IL-9, Cytokine P40, T-cell growth factor P40.
What is the protein family that this protein belongs to?
Belongs to the IL-7/IL-9 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PITM1_MOUSE
Sequence: MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGNGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRIVDTIDIVRDAVAPGEYKAEEDPRLYRSAKTGRGPLADDWARTAAQTGPLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWIELSMADIRALEEETARMLAQRMAKCNTGSEGPEAQTPGKSSTEARPGTSTAGTPDGPEAPPGPDASPDASFGKQWSSSSRSSYSSQHGGGVSPQSLSEWRMQNIARDSENSSEEEFFDAHEGFSDSDEVFPKEMTKWNSNDFIDAFASPTEVEGVPDPTVMATKGIEDGARAPRDSEGLDGAGDLVVEACSVHALFLILHSGSILDSGPGDTNSKQADVQTLSTAFEAVTRVHFPEALGHVALRLVPCPPICAAAYALVSNLSPYSHDGDSLSRSQDHIPLAALPLLATSSSRYQGAVATVIARTNQAYAAFLRSSEGTGFCGQVVLIGDGVGGILGFDALCHSASAGPGSRGSSRRGSMNNEMLSPEVGPVRDPLADGVEVLGRASPEPSALPAQRTFSDMANPDPDGSQNSLQVASTATSSGEPRRASTASCPPASSEAPDGPTNAARLDFKVSGFFLFGSPLGLVLALRKTVMPALEVAQLRPACEQIYNLFHAADPCASRLEPLLAPKFQAIAPLAVPRYQKFPLGDGSSLLLADTLQTHSSLFLEELEMMVPSTPTSASGAFWKGSELGNEPASQTAAPSTTSEVVKILDRWWGNKRIDYSLYCPEALTAFPTVTLPHLFHASYWESADVVAFILRQVIEKERPQLTECEEPSIYSPAFPREKWQRKRTQVKIRNVTSNHRASDTVVCEGRPQVLNGRFMYGPLDVVTLTGEKVDVYVMTQPLSGKWIHFGTEVTNSSGRLTFPVPSERALGIGVYPVRMVVRGDHTYAECCLTVVSRGTEAVVFSIDGSFTASVSIMGSDPKVRAGAVDVVRHWQDSGYLIVYVTGRPDMQKHRVVAWLSQHNFPHGVVSFCDGLTHDPLRQKAMFLQSLVQEVELNIVAGYGSPKDVAVYAALGLSPSQTYIVGRAVRKLQAQCQFLSDGYVAHLGQLEAGSHSHAPSGPPRAALAKSSYAVAAPVDFLRKQSQLLRSRGPSQVDREGPGTPPTTLARGKTRSISLKLDSEE
What is the function of this protein?
Catalyzes the transfer of phosphatidylinositol (PI) between membranes (By similarity).  Binds PI (PubMed:10400687).  Also binds phosphatidylcholine (PC) and phosphatidic acid (PA) with the binding affinity order of PI > PA > PC (By similarity).  Regulates RHOA activity, and plays a role in cytoskeleton remodeling (By similarity).  Necessary for normal completion of cytokinesis (By similarity).  Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus (By similarity).  Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus (By similarity).  Required for protein export from the endoplasmic reticulum and the Golgi (By similarity).  Binds calcium ions (By similarity).
What are the official names of this protein?
Membrane-associated phosphatidylinositol transfer protein 1, Drosophila retinal degeneration B homolog 1, RdgB1, Mpt-1, Phosphatidylinositol transfer protein, membrane-associated 1, PITPnm 1, Pyk2 N-terminal domain-interacting receptor 2, NIR-2.
What is the protein family that this protein belongs to?
Belongs to the PtdIns transfer protein family. PI transfer class IIA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets. Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis.