PharMolix/UniProtQA huggingface dataset:
Protein: F16A1_PARP8
Sequence: MSLQRRTTLTKYLIEQQRENNNLPADLRLLIEVVARACKAISYHVSKGALGDALGTAGSENVQGEVQKKLDILSNEILLEANEWGGNLAGMASEEMEQFFPIPANYPKGEYLLVFDPLDGSSNIDVNVSIGTIFSVLRCPDGQQPTEQSFLQKGTQQVAAGYAVYGPQTVLVLTTGNGVNCFTLDRELGSWVLTQSDMRIPVETREYAINASNQRHWYEPVQQYIGELNAGKDGPRQADFNMRWIASMVADVHRILNRGGIFMYPADKRDPSKPGKLRLMYEANPMSFIVEQAGGAATNGEKRILDIQPKSLHERVAVFLGSKNEVDRVTRYHLEKKS
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 1 1, FBPase class 1 1, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 1.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL7_SALHS
Sequence: MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: PDGFB_FELCA
Sequence: MNRCWALFLSLCCYLRLVSAEGDPIPEELYKMLSDHSIRSFDDLQRLLHGDSVDEDRAELDLNSTRSHCGGELESLSRGRRSLGEAAGSPTVAEPAMIAECKTRTEVFEVSRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRLVQVRKIEIVRKRPVFKKATVTLEDHLACKCETVVAARPVTRSPGSSQEQRARTPQTRVTIRTVRVRRPPKGKHQKFKHTHDKKALKETLGA
What is the function of this protein?
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.  Potent mitogen for cells of mesenchymal origin.  Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta.  Required for normal blood vessel development, and for normal development of kidney glomeruli.  Plays an important role in wound healing.  Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
What are the official names of this protein?
Platelet-derived growth factor subunit B, PDGF subunit B, PDGF-2, Platelet-derived growth factor B chain, Platelet-derived growth factor beta polypeptide, Proto-oncogene c-Sis.
What is the protein family that this protein belongs to?
Belongs to the PDGF/VEGF growth factor family.
What are the subcellular locations of this protein?
Secreted. Note=Released by platelets upon wounding.
Protein: ISPG_PSESM
Sequence: MHGESPIKRRESRKIWVGSVPVGGDAPIAVQSMTNSDTNDVAATVAQINRLEAAGVDIVRISVPDMDAAEAFGRIKQLVKVPLVADIHFDYRIALRVAELGVDCLRINPGNIGREDRVRAVVDAARDRGIPIRIGVNAGSLEKDLQKKYGEPTPEALVESALRHVEHLERLNFKDFKVSVKASDVFMAVAAYRLLAKQIVQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEVKVGYDILKSLRLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPLDVAVIGCVVNGPGEAKEAHIGLTGGTPNLIYIDGKPAQKLTNDNLVDELERLIREKAAEKTAADASVIVRG
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: ATPE_HELHP
Sequence: MENLTLSIVTPYGSIYNGEVKYVVIPGSEGEFGVFPGHCNLLSLLKVGVIEFENLEGNKGLVAINWGHAQISDTDVNIIADGAVAIAGNTESEIVAAISDAKTLLKEASDDSALFGMVVSRVESDYKNFIK
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NADA_GEOSW
Sequence: MNVLEVMKRLDDMPESYKTMSMEEMEVRVRAIKERFGKRLFIPGHHYQKDEVIQFADATGDSLQLAQVAAQNSEAEYIVFCGVHFMAETADILTGDHQKVILPDMRAGCSMADMADITQVERAWPILQELFGDTILPLTYVNSTAAIKAFVGRRGGATVTSSNAKKMVEWAFTQKERIFFLPDQHLGRNTAYELGISLDEMAVWDPHTDRLEYKGDIKKVKVILWKGHCSVHENFTVRHIEYIRRTKPDMNIIVHPECSWDVVQQADYAGSTKYIIETIRNAPSGSKWAIGTEMNLVNRLMHEHPDKEIISLNPYMCPCLTMNRIDLPHLLWALESLERGEIVNQITVPPLIAKDAAQALARMLALA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2822_BORBU
Sequence: MPISKEVNLEEIIKQNVSKSKFAFRDNDVISNNIPNVKPIRSKMTIKQISVGLKYEYWIEFYSILDKKGLTASGFIRTLIMEYIEASKK
What are the official names of this protein?
Uncharacterized protein BBD22.
Protein: GUAA_AGRVS
Sequence: MTQTAHPDSVLIIDFGSQVTQLIARRVRETGVYCEIVPFQSSEEGFARLKPKAVILSGSPASALDEGSPRVPQVIFDSGLPIFGICYGQQTICAQLGGKVEAGHHREFGRAFLEIEQDCKLFEGLWSVGSRHQVWMSHGDRVTAIPPGFRVLATSSNAPFAFIADEARKYYAVQFHPEVVHTPDGAKLIQNFVHNIAGITGDWSMSAYRAKAVEQIRAQVGDKRVICALSGGVDSSVAALLIHEAVGDQLTCILVDHGLMRKNEAADVVAMFKEHYNLHLIHVDAIDRFVGELEGVSDPETKRKIIGRLFIETFEEEAKKLGGADFLGQGTLYPDVIESVSFSGGPSVTIKSHHNVGGLPDRMNMKLVEPLRELFKDEVRVLGKELGLPDSFIGRHPFPGPGLAIRCPGGVTREKLDILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: NS1_HBOC4
Sequence: MAFSAPVLRAFSQPTFTYVIKFPYNNWKEDEHLLWSLLAPGTESLMIQLKNCAPHPEDDPIREDILCSLADLHYGAVFAKACYIATSTLMGQKQRTLFPRCDIVCQSEIGSDFLHCHILVGGAGLSKRNAKISRATLLGLVMAELTQRCKLLLAHRPFEPAEATIYHELKRIEREAWSGHTGNWVQILQYKDKRGDLHAQPIDPLRFLKHYILPKNRLISPSSKPDVCTSPDNWFILADKTYSHTIINGLPLLERNRKAYLQELESEVIPGPSAMAFGGRGAWEQLPEVGEQRLITSNTSTAYKANKKEKLMLNLLDKCDELNLLVYEDLVSACPDLLLMLEGQPGGARLIEQVLGMHHIKVCAKHTALSFLFHLHPDQLLTSSNKALKLLLIQGYNPLQVGHAICCVLNKQMGKQNTICFYGPASTGKTNFAKAIVQGVRLYGCVNHLNKGFVFNDCRQRLIIWWEECLMHQDWVEPAKCILGGTECRIDVKHKDSVLLQQTPVIISTNHDIYSVVGGNTVSHVHAAPLKERVLQLNFMKQLPQTFGEISPSEIAELLQWCFNEYDCTLAGFKQKWNLDKVPNSFPIGDLCPTHSQDFTLHENGFCSDCGGYLPHSADDSVYTDVASETTSGDYDPGNLGDTDGEDSKSEASEVDYCPPKKRRVISATPPNSPVSGPSLSTFLDTWQSQPRDDDELRIYEEQASQFQKNTKSTSEREEAQLGESQEPQPEPDPTAWGEKLGVCSSQQPGQPPIVLYCFEDLRPSDEDEGENIGGD
What is the function of this protein?
Multifunctional protein which displays endonuclease and helicase activities required for initiating and directing viral DNA replication.  Also plays a role in viral packaging and transactivation of several promoters.  Binds site-specifically to 2-3 approximate tandem copies within the origins of replication (Ori), unwinds this hairpin region and nicks one DNA strand thereby initiating the rolling circle replication (RCR).  Becomes covalently attached to the 5' end of the nick and provides a 3'OH for priming DNA synthesis.  The helicase activity unwinds DNA in a 3'-5' direction on the longer strand.  Participates in the transcriptional regulation of several promoters.
What are the official names of this protein?
Initiator protein NS1, NS1, Non-structural protein 1, Non-structural protein NS1.
What is the protein family that this protein belongs to?
Belongs to the parvoviruses initiator protein NS1 family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: SMPX_BOVIN
Sequence: MSKQPVSNVRAIQANINIPMGAFRPGAGQPPRRKECTPEIEEGAPPTSDEEKKPIPGAKKLPGPAVNLSEIQNIKSELKYVPKAEQ
What is the function of this protein?
Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.
What are the official names of this protein?
Small muscular protein.
What is the protein family that this protein belongs to?
Belongs to the SMPX family.
Protein: GET2_ASHGO
Sequence: MSEVSEAEKRRILREKRKQKFSKGAGSARLHKITTQQPGGASGDSTVTSAEISDNEGSLQRGSNSGQSTREIDDLLAAMDPPIEPAEPLESAAPEVAFIQQLMKMQQGSATPPADEKAGGLFSPLLERLAEQEAGGAPVVSGEVGVHQFQVRQLKAYMLLLRWAILLPFIYYVMHPGTAHWLHTSRFLHFVMEPRNFFMVFTTFEVASISIYYQVLLTLERTNKVNSLSYSSKLVTWAGLVPDGMLPIDNLQGKVVVALHYWDILSMYLTDLSLCLVAAGLMKYYHAAP
What is the function of this protein?
Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum.  Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol.  The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.
What are the official names of this protein?
Golgi to ER traffic protein 2.
What is the protein family that this protein belongs to?
Belongs to the GET2 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Protein: ZTRF1_DANRE
Sequence: MSSMEERMELGVAAAPGSSSSGLGVGPVGGALDAGPGSAGLAGIQEESGVRRDGSVGEADPDAPPKKRVRLQEGEAGKLEERLYSVLCCTVCLDLPKASVYQCTNGHLMCAGCFIHLLADSRLKEEQATCPNCRCEISKSLCCRNLAVEKAVSELPSECSYCLKQFPRSGLDRHQTEECQDRVTQCKYKRIGCPWQGPFHELSAHEAECCHPSKTGMELMGILDEMDQSHRRELQLYNSIFSLLCFEKIGFTEVQFRPYRTDDFITRLYYETPRFTVLNQTWVLKARVNDSERNPNLSCKRTLAFQLILKSKVNSALECSFLLLKGPYEDIKIKPVIQHHVFSNDANETEYAPLPICDSVECNKLLAAKNINLRLFIFQIQK
What are the official names of this protein?
Zinc finger TRAF-type-containing protein 1, Cysteine and histidine-rich protein 1.
What is the protein family that this protein belongs to?
Belongs to the ZFTRAF1 family.
Protein: RSSA_DROYA
Sequence: MSGGLDILSLKEDDITKMLVATTHLGSENVNFQMEQYVYKRRADGVNILNLGKTWEKLQLAARAIVAIDNPSDIFVISSRPIGQRAVLKFAKYTDTTPIAGRFTPGAFTNQIQPAFREPRLLVVTDPNTDHQPIMEASYVNIPVIAFTNTDSPLRYIDIAIPCNNKSAHSIGLMWWLLAREVLRLRGTISRSVEWPVVVDLFFYRDPEEAEKEEAAAKELLPPPKIEEAVDHPVEETTNWADEVAAETVGGVEDWNEDTVKTSWGSDGQF
What is the function of this protein?
Required for the assembly and/or stability of the 40S ribosomal subunit.  Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.  Required during oogenesis and imaginal development.
What are the official names of this protein?
40S ribosomal protein SA, Protein stubarista.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=May associate with nascent RNP complexes within the nucleus.
Protein: VP3_ROT41
Sequence: MKVLALRHSVAQVYADTQVYTHDDTKDSYENAFLISNLTTHNILYFNYSVKTLEILNKSGIAAIEIQSLEELFTLIRCNFTYDYENNVVYLHDYSYYTNNEIRTDQHWITKTNIEEYLLPGWKLTYVGYNGNDTRGHYNFSFTCQNAATDDDIIIEYIYSEALDFQNFMLKKIKERMTTSLPIARLSNRVFRDKLFPLLVKKHKRVINVGPRNESMFTFLNFPSIRQFSNGPYLVKNTIKLKQERWLGKRVSQFDIGQYKNMMNVITTIYHYYNLYQEKPIIYMVGSAPSYWIYDVRQYSEFLFETWDPLDTPYSSIHHKELFFEKDIGKLKDNSILYIDIRTDRGNVDWKEWRKIVELQTINNLDLAYKYLATGKSKVCCVKLTAMDLELPVSAKLLHHPTTEIRSEFYLLLDIWDVNNVKRFIPKGVLYSFINNVITDNVFIQSPFKIRTSMSDYIVALYALSNDFNNRADIINLINNQKQSLITVRINNTFKDEPKVGFKNIYDWTFLPTDFDTTNAIVTSYDGCLGMFGLSISLASKPTGNNHLFILNGTDKYYKLDQFANHTGISRRSHQIRFSESATSYSGYIFRDLSNNNFNLIGTNVENSVSGHVYNALIYYRYNYSFDLKRWIYLHSIEKVDIEGGKYYEHAPIELIYACRSAKEFALLQDDLTVLRYANEIENYINKVYSITYADDPNYFIGIKFDNIPYTYDVKVPHLTFGVLYISDNMIPDVVKIMKSMKQELFGMDVTTSYTYMLSDGIYVANVSGVLATYFKMYNLFYKNQITFGQSRMFIPHITLSFRNNKTVRIETTKLRIKSIYLRKIRGDTMFDMSE
What is the function of this protein?
Counteracts the host innate immune response thanks to its phosphodiesterase that degrades the 5'-triphosphorylated, 2'-5' linked adenylate oligomers produced by the host cell IFN-inducible 2',5'-oligoadenylate synthetase (OAS).  The host RNaseL is therefore not activated.
What are the official names of this protein?
Protein VP3.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP3 family.
What are the subcellular locations of this protein?
Virion. Note=Attached inside the inner capsid as a minor component. There are about 11 to 12 copies per virion.
Protein: YIDC_PSEPK
Sequence: MDIKRTILIAALAVVSYVMVLKWNDDYGQAALPTQNTAASTVAPGLPDGVPAGNNGASADVPSANAESSPAELAPVALSKDLIRVKTDVLELAIDPVGGDIVQLNLPKYPRRQDHPNIPFQLFDNGGERVYLAQSGLTGTDGPDARASGRPLYAAEQKSYQLADGQEQLVVDLKFSDNGVNYIKRFSFKRGEYDLNVSYLIDNQSGQAWNGNMFAQLKRDASGDPSSSTATGTATYLGAALWTASEPYKKVSMKDIDKGSLKENVSGGWVAWLQHYFVTAWIPAKSDNNVVQTRKDSQGNYIIGYTGPVISVPAGGKVETSALLYAGPKIQSKLKELSPGLELTVDYGFLWFIAQPIFWLLQHIHSLLGNWGWSIIVLTMLIKGLFFPLSAASYRSMARMRAVAPKLAALKERFGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLALYWVLLESVEMRQAPWILWITDLSIKDPFFILPIIMGATMFIQQRLNPTPPDPMQAKVMKMMPIIFTFFFLWFPAGLVLYWVVNNCLSISQQWYITRRIEAATKKAAA
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CP11A_MESAU
Sequence: MLAKGLSLRSVLAKGCQPFLSPTWQSSVLATGGGANISTNSPRPFNEIPSPGDNGWLNLYHFWRENGTHRIHYHHMQNFQKYGPIYREKLGNKDSVYILDPEDAAQLFLSEGPYPERYLVPPWVAYHQYYKRPIGVLFKSSEAWKKDRLVLNQEVMAPEAIKNFVPLLEGVVQDFINVLHRRIKQQKSGNFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAIYQMFHTSVPMLNLPPELFRFFRTKTWKEHAAAWDMIFKKADDYTQTFYWDLRQKQEFSKYPGVLYSLLGGNKLPFKNIQANITEMLAGGVDTTSMTLQWSLYEMAHNLKVQEMLRAEVLAARRQAQGDMVKMVQLVPLLKASIKETLRLHPISVTVQRYLVDDLVLRNYRIPAKMLVQVANYAMGREPSFFPNPNKFDPTRWLEKSKNTTHFRYLSFGWGVRQCLGRRIAELEMTIFLINVLENFRIELQSLHDVGTKFNLILMPEKPILFNLQPLKKDLGTTTNR
What is the function of this protein?
A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones.  Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal.  Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule.  Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
What are the official names of this protein?
Cholesterol side-chain cleavage enzyme, mitochondrial, CYPXIA1, Cholesterol desmolase, Cytochrome P450 11A1, Cytochrome P450(scc).
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein. Note=Localizes to the matrix side of the mitochondrion inner membrane.
Protein: PSBD_POPDE
Sequence: MTIALGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLVFPCAYFALGGWFTGTTFVTSWYTHGWASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGFWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: ITB2_SHEEP
Sequence: MLPQRPQLLLLAGLLSLQSVLSQECTKYKVSTCRDCIESGPGCAWCQKLNFTGQGEPDSTRCDTRAQLLSKGCPADDIMEPKSLAETRQSQAGKQKQLSPEEVTLYLRPGQAAAFNVTFQRAKGYPIDLYYLMDLSYSMVDDLANVKKLGGDLLRALNDITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKECQPPFAFRHVLKLTDNSKQFETEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKSSNEFDYPSVGQLAHKLAESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSEDSKNVVELIKSAYNKLSSRVFLDHNTLPDTLKVAYDSFCSNGVSQVDQPRGDCDGVQINVPITFQVKVTATECIQEQSFTIRALGFTDTVTVRVLPQCECQCREASRDRSVCGGRGSMECGVCRCDAGYIGKNCECQTHGRSSQELEGSCRKDNSSIICSGLGDCICGQCVCHTSDVPNKKIYGQFCECDNVNCERYDGQVCGGDKRGLCFCGTCRCNDQHEGSACQCLKSTQGCLNLDGVECSGRGRCRCNVCQCDPGYQPPLCIDCPGCPVPCAGFAPCTECLKFDKGPFAKNCSAACGQTKLLSSPVPGGRKCKERDSEGCWMTYTLVQRDGRNRYDVHVDDMLECVKGPNIAAIVGGTVGGVVLVGILLLAIWKALTHLSDLREYHRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES
What is the function of this protein?
Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4.  Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL.  Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen.  Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain.  Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain.  Integrin ITGAM/ITGB2 is also a receptor for factor X.  Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1.  Contributes to natural killer cell cytotoxicity.  Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils.  Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.  Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages.  In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils.
What are the official names of this protein?
Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta.
What is the protein family that this protein belongs to?
Belongs to the integrin beta chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein.
Protein: TM205_XENLA
Sequence: MVAEGDPGNLVKIFHLLVLSASWGMQCWMTFVAGFVLIKGVPRHTFGLVQSKLFPYYNHIVLCCSFISLAIYAAYHPRELLSPSESVQISLFFTSLLVAALQARWFSPVTTKTMFKMHVIEREHSLGQGVGLSANKEGYQLLQEKDPKYKALRKRFMRYHGISSLCNLLCLLCNGANLVYIALLMPTL
What are the official names of this protein?
Transmembrane protein 205.
What is the protein family that this protein belongs to?
Belongs to the TMEM205 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: SUSF_BACTN
Sequence: MKKHLIYTGMFLAAIGFSACNEDFKDWADPQSNPQEESAGQLTATFTAGKDASIVMDAATADSVEIAKLSSTTAEEGSKIAVNSLTLNENHTIPFSMTEDHVFKVALAQLDSVTQEAYKSRASVVRELKISINASAVTPSGEGIQLVGNEVSITLQPATTPAVDPDGYYIVGDFTGWDGNSAQQMKKDALDENLYILEAEIESTSNFKIFPASAINGNDIDWTKALGSSVDGDDSGDNFVSWTNAGAINTALDGKIKISFDAFNYRFTVKDNSAPTELYMTGSAYNWGTPAGDPNAWKALVPVNGTKGTFWGIFYFAANDQVKFAPQANWGNDFGFVDAISQESKDLAGLSDEGGNLKVGIAGWYLVYVSVIGDDKVIEFEKPNVYLMGDTSYNGWDAQLVEQDLFTVPGTADGEFVSPAFLKDGAVRICVNPKAVSAGDWWKTEFIIFDGQIAYRGNGGDQAAVQGKTGQKVYLNFGNGTGRIE
What is the function of this protein?
Starch-binding protein present at the surface of the cell.  Mediates starch-binding before starch transport in the periplasm for degradation.  SusE and SusF do not constitute the major starch-binding proteins in starch degradation pathway.  Has lower affinity for starch compared to SusE.
What are the official names of this protein?
Outer membrane protein SusF, Starch-utilization system protein F.
What is the protein family that this protein belongs to?
Belongs to the SusF family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: TRPC_MYCBO
Sequence: MSPATVLDSILEGVRADVAAREASVSLSEIKAAAAAAPPPLDVMAALREPGIGVIAEVKRASPSAGALATIADPAKLAQAYQDGGARIVSVVTEQRRFQGSLDDLDAVRASVSIPVLRKDFVVQPYQIHEARAHGADMLLLIVAALEQSVLVSMLDRTESLGMTALVEVHTEQEADRALKAGAKVIGVNARDLMTLDVDRDCFARIAPGLPSSVIRIAESGVRGTADLLAYAGAGADAVLVGEGLVTSGDPRAAVADLVTAGTHPSCPKPAR
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: URE1_YERPG
Sequence: MPQISRQEYAGLFGPTTGDKIRLGDTNLFIEIEKDLRGYGEESVYGGGKSLRDGMGANNNLTRDNGVLDLVITNVTIVDARLGVIKADVGIRDGKIAGIGKSGNPGVMDGVTQGMVVGVSTDAISGEHLILTAAGIDSHIHLISPQQAYHALSNGVATFFGGGIGPTDGTNGTTVTPGPWNIRQMLRSIEGLPVNVGILGKGNSYGRGPLLEQAIAGVVGYKVHEDWGATANALRHALRMADEVDIQVSVHTDSLNECGYVEDTIDAFEGRTIHTFHTEGAGGGHAPDIIRVASQTNVLPSSTNPTLPYGVNSQAELFDMIMVCHNLNPNVPADVSFAESRVRPETIAAENVLHDMGVISMFSSDSQAMGRVGENWLRILQTADAMKAARGKLPEDAAGNDNFRVLRYVAKITINPAITQGVSHVIGSVEVGKMADLVLWDPRFFGAKPKMVIKGGMINWAAMGDPNASLPTPQPVFYRPMFGAMGKTLQDTCVTFVSQAALDDGVKEKAGLDRQVIAVKNCRTISKRDLVRNDQTPNIEVDPETFAVKVDGVHATCEPIATASMNQRYFFG
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMP_CAMJ8
Sequence: MNLEALCKEAGLSFYDDELVSENGRKIYRIYVQKEGGVNLDDCARLSEILSPIFDVEPPVNGEYFLEVSSPGLERKLSKIEHFAKSIGELVKITTNEKEKFEAKIIAVDDENITLENLENKEKTTINFNDIKKARTFVEW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_DICNV
Sequence: MTLWQAFILSLIQGITEFLPISSSGHLVITRELLHWQDAGVAFDAFTGLGTLTAVLFYYRKDVCSILYHWFRQFRHCDAPPAPEAKLGNQLIVATLPALLIGFMVKDHIDALTHRPLLIASTTMIFAIFLAAADFWGRKKLSLPETNYRQAFYYGLAQTLALVPGVSRSGITLTAGLAMHFSRESAARFSFLQSIPISAAAGGYGLWKLATNPSDFSWQLIALSYVTATLAAYVCIALFIRFLNTVGMMPHVIYRLLLGAYLFFVFM
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TTR15_CAEEL
Sequence: MRALLFTSVVLLALAFVEAKKQTITVKGTTICNKKRIQAEVTLWEKDTLDPDDKLASMQSNKEGEFSLTGSDDEITSISPYLIITHNCNVKKAGCKRVSEYLIPKEKIGGTYDMTYVTLDILSAKDKEKC
What are the official names of this protein?
Transthyretin-like protein 15.
What is the protein family that this protein belongs to?
Belongs to the nematode transthyretin-like family.
What are the subcellular locations of this protein?
Secreted.