PharMolix/UniProtQA huggingface dataset:
Protein: UBID_AERHH
Sequence: MKYKDLRDFIAQLEQSGQLKRISREIDPYLEMTEISDRTLRAGGPALLFENPKGYTMPVLTNLFGTPDRVAMGMGQPNVAALRQVGIWLSYLKEPEPPRGFKELMEKLPIFKQVLNMPTKRLSSAPCQQRVLEGEAVDLDQIPIQHCWPGDVAPLVTWGLTITRGPYKKRQNLGIYRQQKIGKNKLIMRWLDHRGGAIDFREWQEAHPGERFPVVVALGADPATILGAVTPVPDTLSEYAFAGLLRGSRTEVVKAVSCDLEVPASAEIVLEGYLEPGEMAPEGPYGDHTGYYNEVDEFPVFTITHMTMRKDAIYHSTYTGRPPDEPAVLGVALNEVFVPLLQKQFPEIVDFYLPPEGCSYRMAVVTIKKRYPGHAKRVMLGVWSFLRQFMYTKFVIVCDDDINARDWKDVIWAITTRMDPARDTTLIEHTPIDYLDFASPVSGLGSKMGLDATNKWPGETNREWGQPIVQDEAVKQKIDALWDELNILG
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: TPK_AMOLO
Sequence: MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDDLGERQAEVEKRFFPIVGKLLSG
What is the function of this protein?
Antimicrobial peptide with weak activity against Gram-positive and Gram-negative bacteria and against fungi (PubMed:19843479).  Has been tested against S. aureus (MIC=15. 0 ug/mL), B. pumilus (no activity detected), B. cereus (no activity detected), E. coli (MIC=30. 0 ug/mL), B. dysenteriae (MIC=60. 0 ug/mL), A. cacoaceticus (MIC=75. 0 ug/mL), P. aeruginosa (MIC=25. 0 ug/mL) and C. albicans (MIC=15. 0 ug/mL) (PubMed:19843479).  Also shows a weak hemolytic activity (PubMed:19843479).
What are the official names of this protein?
Temporin-ALk, Amolopin-n1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Temporin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MCMBP_DANRE
Sequence: MPTTHDWINNPLGVVDGLFAQSNSSPDWEKKVVEYFKEKLKLNDAHTWVPSLNDVPLHYLKPNSLVKFRCMVQDMFDPEFFMGVYEMNDPTSNSKQVKCGKYKDVTECGQVDFNSRNTVTSERQTFYCVPIPGESNWVKESYAGTSQARVVPSTSYVPNRHKRSYEEDDEMDTQCQQTKDISQGAQSSSESHGNTEPKRQETEAPSQDSSSSHCTSSLDLNFPLPGEKGPACLVKVYEDWDSFKLNDMLEVFGILSVDPALSVIADEREASSLLDPTEGMETMEEQRVHSPPASLVPRLHMLYAQPLAHNNPLLPSSPLENNADYLSCVLGELASVRAELLTFFTHILMGDSLAAEFLILHLISNVYSRRDVLPLGKFTLNLSGCPLSSPFTEHLFKVIQQLVPSSYRLSMSLHNMNTQRMVPRKDYTANRLVSGTLQLAKNTSLFLDETQLEQGQLDSTGVRNITALGNLISWQKVDYDFNYHQMEFPCNINVLIASEGRSLLPSDCQVHLRASLNPPNLEEYLSAVQVAQVPSQLNKYRVYLSVARALNYTISDEITKAVEEDFVDMRKDDPQSMSAEDLHRLLVVARLLSLSHGQNTLSRDGWMKAKQLEALRISRTQQQKCVNGNEP
What is the function of this protein?
Associated component of the mcm complex that acts as a regulator of DNA replication.  Binds to the MCM complex during late S phase and promotes the disassembly of the mcm complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA.  Can dissociate the mcm complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the mcm complex.  Required for sister chromatid cohesion (By similarity).
What are the official names of this protein?
Mini-chromosome maintenance complex-binding protein, MCM-BP, MCM-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MCMBP family.
What are the subcellular locations of this protein?
Nucleus. Note=Associates with chromatin.
Protein: ATPD_NATTJ
Sequence: MIIPKRYAEALFQLAKEREKINEITQSFNQLIERLRSNEEVFKLLSYPVVDIAEKKQVADELTADLEQEIRDYLKVLIDNKRTDELAEIHDTFLDLVRTEENRTLCEVKTPIPLDEDELKKIQDLLAQMSEGEVEIETTTDESIIGGIVVRIGDRVFDYSLKGQLNSLREQLKKTTITS
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: PUSH_ARATH
Sequence: MAVSFLRIPIPSRVFWYPTRLIRVTPALLRFSSSAAFQPSSTSLSPPSSDNFLADKWESYRKKKVVIRIGYVGTDYRGLQIQRDDPSIKTIEGELEVAIYKAGGIRDSNYGDLHKIGWARSSRTDKGVHSLATSISLKMEIPETAWKDDPQGTVLAKCISKHLPENIRVFSVLPSNRRFDPRRECTLRKYSYLLPVDVLGIKNSFTSDEIDYHITDFNEILKEFEGEYPFHNYTQRSRYRRKSEQKIKQRNGRPPREPKSIKASESEFREENHIEIGEEEEEKEVDGESDEHVVTPDSDNSQVYSRAKWLYEPDETDKISGAHFRKVFRCRSGKLENSLGFGFVEISIWGESFMLHQIRKMIGTAVAVKRELLPRDIIRLSLNKFTRIVLPLAPSEVLILRGNSFEVRRLPERPGMEATGESEEVEKEIEEFYRAVMVPQVSIFLDSEKSPWKEWVDHLDRNDGLIDEELEDVRKGWEEWKAAKPWMNLKKTEDDEEALSSVSVPIHQAL
What are the official names of this protein?
Putative tRNA pseudouridine synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: CAPSD_HBVC7
Sequence: MDIDPYKEFGASVEVLSFLPSDFFPSNRDLLDTASALDREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
What is the function of this protein?
Self assembles to form an icosahedral capsid.  Most capsids appear to be large particles with an icosahedral symmetry of T=4 and consist of 240 copies of capsid protein, though a fraction forms smaller T=3 particles consisting of 180 capsid proteins.  Entering capsids are transported along microtubules to the nucleus.  Phosphorylation of the capsid is thought to induce exposure of nuclear localization signal in the C-terminal portion of the capsid protein that allows binding to the nuclear pore complex via the importin (karyopherin-) alpha and beta.  Capsids are imported in intact form through the nuclear pore into the nuclear basket, where it probably binds NUP153.  Only capsids that contain the mature viral genome can release the viral DNA and capsid protein into the nucleoplasm.  Immature capsids get stuck in the basket.  Capsids encapsulate the pre-genomic RNA and the P protein.  Pre-genomic RNA is reverse-transcribed into DNA while the capsid is still in the cytoplasm.  The capsid can then either be directed to the nucleus, providing more genomes for transcription, or bud through the endoplasmic reticulum to provide new virions.
What are the official names of this protein?
Capsid protein, Core antigen, Core protein, HBcAg, p21.5.
What is the protein family that this protein belongs to?
Belongs to the orthohepadnavirus core antigen family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: PTC71_DROPS
Sequence: MAFMRSKPSLGSLARVAFRWCGPGVGLVNYSQEPYLVKAVQGKSKPRSPTLQSAMQPRAQAETIQAPKCFGEDSFFFSSTPKADVMGVADGVGGWRDRGIDAGRFSRDLMQRCFVHAQKPTFDGRNPRQLLSECYGEMKRKWKPILGSSTACVVAFNRSESALYTANLGDSGYVVIRNGSVLDRSEEQTHFFNMPFQLTVPPPDSNREMWFCDDPSEAVATRLLLQPDDLVLVATDGLFDNMPEQMLLEMLSKVQGVHEQKAIQEAVNRVVERAGALSINPIYKSPFCLRALENNVAYGGGGKPDDITVVLASVAMRQCNTVGDSNESKGSDLRPRLSFP
What are the official names of this protein?
Protein phosphatase PTC7 homolog fig, Fos intronic gene protein.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: RPO3_PYRFU
Sequence: MAGIEVQILEKKEDSIKFVLKGVHVSFANALRRTILGEVPTFAVDEVEFYENDSALFDEIIAHRLAMIPLTTPVDRFELDALELDDYTVTLSLEAEGPGIVYSGDLKSDDPDVKPVNPNIPIVKLAEGQRLVFNAYAKLGRGKDHAKWQPGFVYYKYYTIVHISKSIPEWKELKKLAKKRGLPVEETEEEVLVTTIKPFYIPKDFEEYEGKEIWEEIVPNTYIFTVETNGELPVEEIVSIALKILMRKADRFISELQKLTS
What is the function of this protein?
DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit Rpo3, DNA-directed RNA polymerase subunit D.
What is the protein family that this protein belongs to?
Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSTK1_HUMAN
Sequence: MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLPRKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRELWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL
What is the function of this protein?
Glutathione S-transferase that catalyzes the conjugation of glutathione to exogenous and endogenous compounds (PubMed:14709161, PubMed:14742434).  Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB) (PubMed:14709161).
What are the official names of this protein?
Glutathione S-transferase kappa 1, GST 13-13, GST class-kappa, GSTK1-1, hGSTK1, Glutathione S-transferase subunit 13.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Kappa family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: YOQU_BACSU
Sequence: MPNQEQIKRMNDINDLIKLIASIDHRTFYRKSKDRIAYFRFKKKLFFVDDYTGDDVYPYEMGYGSPNGFSHGGNMWQLVNSFRKFIITGKCGELRDYKEIWAYSYEGCMKIRQKAKEIGFIETVDYPYSFDEWMNTN
What are the official names of this protein?
SPbeta prophage-derived uncharacterized protein YoqU.
Protein: OMPC_ECOL6
Sequence: MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLGFKGETQVTDQLTGYGQWEYQIQGNAPESENNSWTRVAFAGLKFQDIGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGQNGSVSGENDPDFTGHGITNNGRKALRQNGDGVGGSITYDYEGFGVGAAVSSSKRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLDDNQFTRAAGINTDDIVALGLVYQF
What is the function of this protein?
(Microbial infection) Is not susceptible to CdiA-EC536-mediated toxicity, which uses OmpC-OmpF heterotrimers of some strains as its outer membrane receptor.  Mutagenesis of extracellular loops L4 or L5 of this protein confers susceptibility to the toxin.
What are the official names of this protein?
Outer membrane porin C, Outer membrane protein 1B, Outer membrane protein C, Porin OmpC.
What is the protein family that this protein belongs to?
Belongs to the Gram-negative porin family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CLIC4_RAT
Sequence: MALSMPLNGLKEEDKEPLIELFVKAGSDGESIGNCPFSQRLFMILWLKGVVFSVTTVDLKRKPAHLQNLAPGTHPPFITFNSEVKTDVNKIEEFLEEVLCPPKYLKLSPKHPESNTAGMDIFAKFSAYIKNSRPEANEALERGLLKTLQKLDEYLNSPLPGEIDENSMEDIKSSTRRFLDGDEMTLADCNLLPKLHIVKVVAKKYRNFDIPKGMTGIWRYLTNAYSRDEFTNTCPSDKEVEIAYSDVAKRLTK
What is the function of this protein?
Can insert into membranes and form poorly selective ion channels that may also transport chloride ions.  Channel activity depends on the pH.  Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions.  Promotes cell-surface expression of HRH3.  May play a role in angiogenesis (By similarity).
What are the official names of this protein?
Chloride intracellular channel protein 4, Intracellular chloride ion channel protein p64H1.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Membrane; Single-pass membrane protein. Cytoplasm. Cytoplasmic vesicle membrane; Single-pass membrane protein. Nucleus. Cell membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain. Present in an intracellular vesicular compartment that likely represent trans-Golgi network vesicles (By similarity).
Protein: HIS4_CHLCH
Sequence: MLIIPAIDIKDGKCVRLTRGDFSQKKIYLDNPSDMAIIWRKQNAKMLHIVDLDAALTGEMVNIAAISDIVANVDIPVQVGGGIRSVDAVKSYLDIGVARVIIGSAAVTNPKLVEELMHIYRPSQIVVGIDAENGVPKIKGWLESATMQDYELALRMKEMGIERIIYTDITRDGMMQGIGYESTKRFAEKAGMKVTASGGVTNSSDLHKLEGLRRYGVDSVIVGKALYECNFPCQELWYSFEDEISIDHNFSTARQKS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAP1S_MOUSE
Sequence: MAAVMAAPEAVEAPSSLLLLVVGGECGCPGLLAYVMEELERGVRSWEDVDPAVCSLDEQLKAFVSRHSATFSSIVKGQRSLHHRGETLETLVLLNPSDKSLCDELRNLLMDPAPHKLLVLAGPCLEETGELLLQTGGFSAHHFLQVLGDKEVQDALASAPAAPALTVSCPTFGDWALLGPVPGLQLRLNPPAQLPASEGLRAFLEYVAESLEPPSPFELLEPPAAGGFLRLARPCCYVFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHAGADSLPGLNSLLRRKLAEREAAAGPQGQHEERLRRLLSPALGVVFLNAREAASRLRGGEDEAVCARSLLRSLGIAPLPLQRGPQPSCPTVLFEKLGVGRLELFVLHPPPGDPAAPACALLVWQPAAPGDKVVRVLFPGRTPPARLLDGLQRLQHLPCLRRPVVTTHDLEAPSRANSQDSLASRDSARKEPVRGTVGSIANRSTVRREPALATRDQKKDTRSGPTQPTARDTRRSGPGVVNTKPRVSQNGPRAPVLAAPLTAPVAECPGEAENILESERPPAPSPTLSPAQSPPPTAPGNSPERLSLSPLRPEPAPDASPSATTPTLTTPSLPAELGSPHSTEVDESLSVSFEQVLPAGDPGLSLPLRLARRSTSPHDVDLCLVSPCEFSHRKPPPPASPGSSDSSARSQERPPETPPTSVSESLPTLSDSDPVPVADSDDDAGSESAARDPPPTPRVPPPLPDVPGICMVDPEALPPRARQPLNTTNPSRSRKAPARPSSASATPRAATVAAKTKGPAGDRNRPLSARSEPADRPGRVPLTRKPSVPKTVPKMASATRLSSGPSGRPAPLAAGSPVYLDLAYLPGGGAGHLDQNFFLRVRALCYVISGQGQRQEEGLRAVLDALLAGKRQWDLDLQVTLIPTFDSAVMHRWYEETHAQHQALGIRVLGSGSLVSMQDEAFPACKVEF
What is the function of this protein?
Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD).  Plays a role in anchoring the microtubule organizing center to the centrosomes.  Binds to DNA.  Plays a role in apoptosis (By similarity).  Involved in the formation of microtubule bundles.
What are the official names of this protein?
Microtubule-associated protein 1S, MAP-1S, BPY2-interacting protein 1, Microtubule-associated protein 8.
What is the protein family that this protein belongs to?
Belongs to the MAP1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle. Note=Detected in perinuclear punctate network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1. In interphase cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different stages of mitosis detected at the spindle microtubules. Detected in filopodia-like protrusions and synapses (By similarity).
Protein: EFTU_EIKCO
Sequence: MAKGKFERSKPHVNVGTIGHVDHGKTTLTAALTTILAEKFGGQAKA
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHEB2_BURPS
Sequence: MNIGIVNDLPLAVEALRRTIALRPEHRVLWVATDGAQALDFCVAQPPDLVLMDLVMPRIDGVSATRSIMERSPCAILIVTANVGANASYVYEAMGAGALDAVDTPTLEQGGSADPSQPLLAKIDQIGRLLATRMPLAAPAAAAPAPQGALPPLVAIGASAGGPTALTALLRRLPDDFPAALVIVQHVDQAFAIGMAQWLDGYSPLPVRIARQGSVPQAGEVLLAATNDHLHLTSRGVLAYTRRPEETPYRPSVDVFFHSVVDHWKGEAIGVLLTGMGRDGALGLKAMRTKGHYTIAQDEATSAVYGMPKAAAAIGAASAVLPLERIADQLISLVQRNRQRWR
What is the function of this protein?
Involved in chemotaxis.  Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli.  Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR.  Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
What are the official names of this protein?
Protein-glutamate methylesterase/protein-glutamine glutaminase 2.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLKA_THEKO
Sequence: MNWDGLYASAFERIRDNIGKVGNVLLAYNTNIDAIKYLEREDLERRIGAAGREEVLPYSEKLPKRIESVPQLLGSILWSIRRGKAAELFVESCSTRFYMRRWGWDELRMGGQVGIMANLLGGVYGVPVIAHVPQLSRLQAELFKDGPIYVPKVEGGKLKLVHPKEFKADEENCIHYIYEFPRGFRVFDFEAPRENRFIGSADDYNTNVVIRPEFEEHFGEIAEKTELAIISGLQALTEGNYREPFETIKEHLDVLEGKGIPAHLEFAFTPDETVRKEILGVLGKFWSVGLNEVELASIMDVMGEKTLAEKLLAHDPVDPIVVTKAMLKLAEKTGVRRIHFHTYGYYLALTDYRGEFVRDALLFAALAAAAKAKLGDVRNIDDVVKAMDVPVNEKAKGVEEALTKEYGMENGIAEVNGYQLAFIPTKIVAKPKSTVGIGDTISSSAFVGEFALR
What is the function of this protein?
Catalyzes the ADP-dependent phosphorylation of D-glucose to D-glucose 6-phosphate and glucosamine to glucosamine 6-phosphate.  Involved in chitin degradation.
What are the official names of this protein?
ADP-dependent glucose/glucosamine kinase, ADP-dependent glucokinase, ADP-GK, ADPGK, Glucosamine kinase, GlcN kinase.
What is the protein family that this protein belongs to?
Belongs to the ADP-dependent glucokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLYA_BRUA1
Sequence: MSQANAATKAYSDVFFNASLEDIDPEIFGAIRNELGRQRHEIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRYYGGCQYVDVVEELAIERAKKLFGAEFANVQPNSGSQMNQAVFLALLQPGDTFMGLDLNSGGHLTHGSPVNMSGKWFNVVSYGVRKDDHLLDMDEVARLARENKPKLILAGGTAYSRIWDWKRFREIADEVGAYLMVDMAHIAGLVAGGQHPSPVPHAHVCTTTTHKSLRGPRGGMILTNDADIAKKINSAVFPGLQGGPLMHVIAGKAVAFAEALKPEFKLYAKNVVDNARALAEELKSHGLDIVSGGTDNHLMLVDLRPKNATGKRAEAALGRANITCNKNGIPFDPEKPFVTSGVRLGTPAGTTRGFGVAEFKEIGSLIAEVLDGLKVANSDEGNAAVEQAVKEKVIALTGRFPMYGYQG
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAJ_CAMJ8
Sequence: MEISYYEILEITQSADKETIKKAYRKMALKYHPDRNQGDKEAEDKFKLVNEAYEVLSNDEKRAIYDRYGKDALKGGGFGSSSSGFGGFEDLGDIFSSFFGEGFGSSSRRRKSSNDEKIPSDFIVNLKLSFKEAVFGCKKNIDFTYKCSCKTCNGTGAKDGKLQTCPKCQGRGQVGVSQGFITFAQTCPDCQGSGEKASEKCSDCKGLGYNESKDSVELNIPEGIDTGMKLRVNAKGNILKNGTRGDMYVKIIAAEDDTFVRDDDDIYIEFPVFFTQAILGQSIKVPTIRGEATLNLPKGAKDGQRFVLEKEGVKDVHSSRIGNQIVQISIKFPTSLNDEQKELLEKLSESFGIKDGMHQEQKGLFEKIANWFKS
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPH_MARPO
Sequence: MNPLISAASVIAAGLAVGLASIGPGIGQGTAAGQAVEGIARQPEAEGKIRGTLLLSLAFMEALTIYGLVVALALLFANPFV
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, chloroplastic, ATP synthase F(0) sector subunit c, ATPase subunit III, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: KDSB_KLEP7
Sequence: MSFVVIIPARFASTRLPGKPLQDINGKPMIVHVLERARESGADRIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTIIVNIQGDEPMIPPAIVRQVAENLAASSSGMATLAVPIHDAEEAFNPNAVKVVMDAKGYALYFSRATIPWDRDRFAQSRETIGDSLLRHIGIYGYRAGFIRRYVSWAPSPLEQIEMLEQLRVLWYGEKIHVAVAAEVPGTGVDTPEDLERVRAELR
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MRD1_KLULA
Sequence: MSRVIVKGLPIYLKEDRLRDLIEKRLTQKHQSTDVQSYLSDVKLMKNRDGESRRFAFIGFRDEEDAFDCVNYFNGTFVDTSKIEVSMAKSFADPRVPQPMREKRREALKRLREREELLLADKKDSQKKQKSDSNNDGGKKHDIDAEIAKNKQLQEFINTMKPSSQVTSWETVQSSKTQGEDEEAADDEVGEMSSNPLLSQALALKGNSRDADEDTDMFKLPGNESDDEYVSLNGGSNNANTDEPEPQMMSLDTFDTAGPTSTDDMAKDEAVSDLDWLKNRRVRIKDGADTPVSKQQQQPDTEQQQPEETEVETSQESEEEKSLKKIRETGRLFLRNILYTATEDDFRKLFSPYGELEEVHIAVDTRTGQSKGFAYVLFKNADNAATAFVELDKQIFQGRLLHILPADAKKSHKLDEFDLKNLPLKKQRELKRKANSAQQTFSWNSLYMNQDAVLSSVADKLGMKKSELIDAENSSSAVKQALAEASVIGDVRKFFETRGVDLTKFAQLKNSERDDRVILVKNFPYGTTREEIAELFLPFGKLQRLLLPPSGTIAILQFRDVPAARAAFSKISYKRFKDGIIYLEKGPSDCFTRDAQGDELVESETDIQKATAKEAKISGADLLEAQSLPAADKDDHDDDDDDDDVQAGPTVSIFIKNLNFSTTSQQLTEKFKPFNGFVVAQVKTKPDPKQPGKTLSMGFGFAEFKTKEQANAVISAMEGTILDGHKLQLKLSHRQGTSTTNASSKKKKKNQGKIIVKNLPFEATRKDVFELFSSFGQLKSVRVPKKFDKSARGFAFVEFLLPKEAENAMDQLQGVHLLGRRLVMEFVEQDPEDVEQQIEKMTRKVKKQVNTTKIANMRNSGKRKIDLDEDDENDGLQG
What is the function of this protein?
Involved in pre-rRNA processing.
What are the official names of this protein?
Multiple RNA-binding domain-containing protein 1.
What is the protein family that this protein belongs to?
Belongs to the RRM MRD1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TUSE_BUCAI
Sequence: MNTDNKILYTYENLEKDSEGYLKKTKDWNIKLAEEIAKRENITLSSDHWKVIIFVRKFYFKFNITPSMRMLIKSIQKEIGKSKMNSIYLFKLFPKGPAKQASKIAGIPKPVKCL
What is the function of this protein?
Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.  Could accept sulfur from TusD (By similarity).
What are the official names of this protein?
Sulfurtransferase TusE, tRNA 2-thiouridine synthesizing protein E.
What is the protein family that this protein belongs to?
Belongs to the DsrC/TusE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METXA_GEOMG
Sequence: MSVGIVQEQSVTFDTELRLESGRILGPITLAYETYGELNADRSNAILVAHAWTGNAHLAGKNSEEDTKPGWWDAIVGPGRLLDTDRCFVICSNVIGSCYGSTGPASINPKTGKRYNLTFPVITVRDMVRAQALLLDHLGIDRLLTVLGGSMGGMQALEWATQFPDRIRSAIALATTSRPSPQAISLNAVARWAIFNDPTWKKGEYRKNPKDGLALARGIGHITFLSDESMWQKFGRRFNARDGLFDFFGQFEVERYLSYNGYNFVDRFDTNSFLYLAKALDLYDTAWGYESLEEAFSRVKAPIQFFAFTSDWLYPPYQTEEMATILRSLGKPVEYHLIESAYGHDAFLLEHETFAPMVREFLDKVERSE
What is the function of this protein?
Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
What are the official names of this protein?
Homoserine O-acetyltransferase, HAT, Homoserine transacetylase, HTA.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIDD_STAAT
Sequence: MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.