PharMolix/UniProtQA huggingface dataset:
Protein: FRPD1_MOUSE
Sequence: MEELDGSLSQTRKAHRIEQMVARWLRRSRDSSARAKVAAADGPPGNPAQALTPVRHTVTLDKDVLLQNYGFHISETLPLTVVAVTAGGSAHGKLFPGDQILQMNNELAEDLSCERAADILRETEDALSITVVRCTSGVPKSSFLTEEKRARLKSNPVKVHFAEEVLVSGHSQGNSLLCMPNVLKVYLENGQTKAFKFEANTTVKDIILTVKEKLSIRSIEYFALALEEQYSISRLHLLHEEELVQQVVEREESQDSRCLFRVSFVPKDPLDLLKEDPVAFEYLYLQSCSDVLQERFAVEMKCNSALRLAALHIQERIYACAQPQKISLKYIEKDWGIENFISPTLLRNMKGKDIKKAISFHMKRNQNLLEPRQKQLISAAQLRLNYLQILGELKTYGGKVFNATLMLQDRESYIALLVGAKYGISQIINSKLNIISTLAEFANISRVELTEESEKVSMVKVYLQDVKVLTLLLESSSAKDLACLIAGYYRLFVDPANSVFHWSGNRRPTHRVSAEEGYESRACSDSEESSEVDCVLEPLSDRCLVKLSLCRPFAREEQPPGDSPTPEATRRGPSTCGASSMTDSAESEASDSANTESRGCRTSGSSESMDALEEDDLDACSSSGTSFFHFGPPGFSKGLETNSQEENSRVETSGFLCLLDLGQNANPQCQKIDGPQGLASEACSWGPELSMGRLDPRLYEGSRTDYYNLCSSISPGSHLSDSGSESTASRQGAAPPQWCQQGWMEAQSGSMLESLGLPALPPLAFEGGSSDEEYYDAADKLTPPDTLSGPRAADPSAMRLQSQSRTRGSEESLHPGPEGGEPSRQGGVKKYAKSLRKRRSFLQTDHTSQVSFPLEASASQENTDDVCYYDREPYLTLTAPSPTVSSLQDMQGEPGLLETKALGLLASLRETKSTNPASRIMEMEPETMETKSVIDSRVSSISAIRLRIDPSNTENPVTTDGSSASIPHSPHHSNPGSSSPQAAQVRPFPIVSPDQDPGGTTPKELTAEPEDSTFPLSSDHPNPDNPGPHHVSQGDTSELGEVRSEIGSESFLINHVQEVIPQITGPLCPGDGPTSGECEVNSEETALAADEVQGQLSLDSDREVMHRNGPSLFQKGSGKDLGDSKGDRLDNVPQALDVRAPAGEINSSLCSEPPATGTGQTSSDSEGENREAQEQELLTELDLAPDFLLPSAFPPETIKAEQLDRVIGEDSVPVSTSQQVCVHTVPSLPKLSPCQEEPRSADSGHGSPAESKGDDSPIICLPPERSFLCFAPESHPEGSTSLSRVTSFSFAGINEVAPAEIGIEHCRCQFSYATCFRGLQPETEEEDGDPQTHPAAPLTSPPSAGSQVTLPWRAARAYSCTTPLSRKSHIWPEFCSRALRQLKTTPTNAPEGFVQLTESLLELQDILEASWGVGNKHPPDKCTLHFSESRSRLCMGSQKLLASCQHVIRMDQSPEEMQGAVRVTFQHLVQLAGLCFQFTDCSRCSTRHREVAGNLRDVVYTYHQFVEAAKLTCERGYHDFSVKLLARQCTALTAAVFCLTQKFRASTAL
What is the function of this protein?
Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.
What are the official names of this protein?
FERM and PDZ domain-containing protein 1.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Found both in the cytoplasm and associated with the cell membrane.
Protein: MUTS2_CLOAB
Sequence: MNEKSLRVLEYFKIKDGIKKYISTSAAKKLIDELEPYGSLYEVKEHIEETKEAFELLMKKGAPPFEGAYDVTEAVSMAEKGFSLAPGQLLKVGSMLRCARKFKEYISHKEEEESYRIIEDICSGIIPLKNIEDNIFNAIIGEEEISDKASTALYSIRRSLKDKNASIKDKVNAMMRSYSKYLQENLYTIRGERYVIPVKAEYKAQVPGLVHDQSSTGATLFIEPMGLVNLNNEIKELMLKEKAEIERILRELSALIYKSIVAVKNNEKIVTELDFIFAKAKYASSINATAPHVNDKGVIDIVMGRHPLIDPAKVVPLNIYMGREFTSLVITGPNTGGKTVTLKTTGLLEVMAMSGLMIPARENSTISFFKEVYADIGDEQSIEQSLSTFSSHMTNIVRIIDDADEDSLVLFDELGAGTDPTEGAALAISILEALRKRGTKIVATTHYSELKAYALKTENVENASVEFDVETLRPTYRLLIGIPGKSNAFEISKRLGLSDYIIEEARKGISKDTLEFEDLIQNLQTRSVKAEENLRKAEFLKEQAEKFKEKYEEKVSSITETREKALHEGRREAKKIIEEAKSEADKILKDMREMERLGYSSEARQRLQESRQKLKEKLNNAEESLNISERDQGEALKSVKEGEEVFIPSLNMKGIVISTQDSKGEVGIQAGIMKINVKLKDLRKTNNNPISKKEKAVKKREARLNLKSVAQSIDLRGLDSEEAIYKTDIYLDEAYMAGLGSVTVIHGKGTGVLRNAINTMLKKNSHVKSYRLGNFGEGGTGVTVVELK
What is the function of this protein?
Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.
What are the official names of this protein?
Endonuclease MutS2.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
Protein: EIF3H_DROAN
Sequence: MANRGGRHARNEESDNTINYVQCDGLAVMKMVKHCHEESSNMDLAQGALLGLVVDKCLEITNCFPFPKSGDETMDEEMYQLTVMRRLRRVNVDHLHVGWYQSSDVGNSLSLALLESQYHYQTSIEESVVVVYDTQKSSRGFLCLKAYRLTPQAIQMYKDGDFTPEAFRTLKVGYESLFAEIPIVIKNSPLTNIMMSELNELLPEDKGHNFLDLGTASVLENHMRSLIERVDELYQEAVRYNKYQQVVFKQDTEKHRALAKLAAENAVRTSKGEPTVPEEEVIKQFRPMPVPARLTATITSGQINTHAQHIAQFCSQSLAKLFITESLQNAKEAKETK
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit H, eIF3h, Eukaryotic translation initiation factor 3 subunit 3.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_BORHD
Sequence: MKITILSLFPSIITPFFENSIMKKVVDRGIISYEVISIRDFSDDKHKRCDDIPYGGGAGMVLKAPPISAALEYVNAKSKTTIFVSPSGLKYTQKLAYDLSKKSELVIICGRYEGLDQRVIDLYVDLEVSVGDYVLSSGEVAALVIIDSVYRLLDGAINPSSLLEESFSFDCGLLEYPHYTRPYEFKGLEVPDVLLSGHHEEIKKWRFIKSVEKTKKNRYDLYLKYLEMIGENDGFSKKN
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y270_MYCPN
Sequence: MQYTVLIPLFIFIGAMVLFGFSFQKKQPQRRIVQILFLAYCVDFLALIIAVMMLTFLSYDDLMLGVLIPVLILSIIMFFVMIIAHYPLMKRLFGH
What are the official names of this protein?
Uncharacterized protein MG131 homolog.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: FUS4_GIBM7
Sequence: MLTIATLHVALQVFGAFSPSHAAAVTLEHRSARDGNSVAVPANWDVYGYLFNVTVGSPPQNITMLSDMTWMAPFVRSGRCLGQFNPELCVAQGQSFFNEHNSTTFANTTFAQATWPVTAFAPNFTVDYGRDKFCIGEICNKDTLMQVSDFPYPGSVVPVIPFGGIFGLAPTPEAITATSEPVNFQAWKNGKMGPLVGWHTCEVLKSAATCQGGDAQLVFGGTDTTMYSAKKLQSYEIQNPEWLSDAFYPSTPPRSNYWSTSLTGMWIRTDKLSKNYAVPFKAVKTAKRTPPLAVVDEGSEGLGAPLSLNGYKYLVRHIKSAKLASKAIVQNIQQQGSSGYNTADQDWYTVACDGLHEYPDLVYQLDGRKKYTISAGDYVTKLTDMPGSVCYLNINVWKYGRTENGDARVVLLGRAFLKRKYLVLNFEDRSFGLAPLRTG
What is the function of this protein?
Secreted aspartic protease; part of the gene cluster that mediates the biosynthesis of the mycotoxin fusarin C (PubMed:22652150).  Within the cluster, FUS1, FUS2, FUS8 and FUS9 are sufficient for fusarin production (By similarity).  The other FUS cluster members are not essential for fusarin C biosynthesis (By similarity).
What are the official names of this protein?
Secreted aspartic protease FUS4, Fusarin biosynthesis protein 4.
What is the protein family that this protein belongs to?
Belongs to the peptidase A1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: FOXL2_HUMAN
Sequence: MMASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
What is the function of this protein?
Transcriptional regulator.  Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination.  Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity).  Has apoptotic activity in ovarian cells.  Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity).  Is a regulator of CYP19 expression (By similarity).  Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity).  Is a transcriptional repressor of STAR.  Activates SIRT1 transcription under cellular stress conditions.  Activates transcription of OSR2.
What are the official names of this protein?
Forkhead box protein L2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SUT3_ORYSI
Sequence: MAVDMELDGGGDGKGKAPPQISLSGLFLACMVAGGVQYGWALQLSLLTPYIQTLGIPHALTSVMWLCGPIAGLIVQPCVGLYSDKCTSSLGRRRPFILTGCIIICISVIVIGFSSDIGYALGDATEDCKVYRGPRYHAAAAFILGFWLLDFSNNTVQGPARALMADLSGRHGPSAANAIFCSWMALGNILGYSSGSTNDWHKWFPFLMTRACCEACANLKAAFLVAVVFLGLSTAVTMVFAREVALDPVAAAKRNEGEASGPLAVFKGMKNLPVGMPSVLIVTGLTWLSWFPFILFDTDWMGREIYHGRPDGSPAEVTAFQEGVRQGAFGLLLNSIVLGISSFLIEPMCRRLGARAVWVMSSAVVCVAMAAVSVLSAWSLGDFGGSVQDAARAPAEEGGVRASALALFVFLGLPFAVLCSVPFAVTAQLTASRGGGQGLCTGVLNISIVVPQMAIALGAGPWDELFGEGNIPAFAMASVFAAAAAAAGVVLLPKVSVRSVSMAGGH
What is the function of this protein?
Responsible for the transport of sucrose into the cell, with the concomitant uptake of protons (symport system).  May also transport other glucosides (By similarity).
What are the official names of this protein?
Sucrose transport protein SUT3, Sucrose permease 3, Sucrose transporter 3, OsSUT3, Sucrose-proton symporter 3.
What is the protein family that this protein belongs to?
Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2.4) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: GCH1L_STRP6
Sequence: MKAKILIDAYEAFCPLDLSMEGDVKGLQMGSLDKDIRKVMITLDIRESTVAEAIKNEVDLIITKHAPIFKPLKDLVSSPQRDILLDLVKHDISVYVSHTNIDIVPGGLNDWFCDLLEIKEATYLSETKEGFGIGRIGTVKEQALEELASKVKRVFDLDTVRLIRYDKENPLISKIAICGGSGGEFYQDAVQKGADVYITGDIYYHTAQEMLTEGLFAVDPGHHIEVLFTEKLKEKLQGWKEENGWDVSIISSKASTNPFSHL
What are the official names of this protein?
GTP cyclohydrolase 1 type 2 homolog.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
Protein: POB3_CRYNJ
Sequence: MSTVTFENIFHGDSADLGKLRFNPVGFGWKAYQSEDNNPTTYNGSDIRHATWFRVARHFQLRLGMRNSEKPRISFDGFKRDDLDKIKRTLQEYFNITLETRDTSLKGWNWGEAQVKGSDLVFQVQGKTAFDVPLSQVANSNIAGKYEVALEFNPPSNYKFDPKDLNKRPPDEMVEMRFYIPGKSMKKAGSDAGSGGEETELDEEGNEVSAADAFHSLIKEKADIGAVVGDSIVVFEDCLILTPRGRFSIEVYADSIRLVGKSTDHRVPFTSIHRIFLLPKLDDLHVQLVLGLDPPIRQGATRYPFLVAQWPKDEVVNAELNLTDEELAQYPDLEKTYEATTFQVVSRVLKALTGKKVTPPGSLRNAQGLNGIRANVKAVQGELYFLEKGLIFISKQPILIDFSKTDSISFSRVGGGVASARTFDMRVVSKTGGADHVFSAINKQEVGPISSFLQSKNIRLKNEMEEAIVDIDEPFSDDDEEMESPSEDERPSKAKNDKSKTKPVKKAADDDEDESDDEDFEDESSDGGSPSESDSDDDSGMASDASDPMMEELRKKTQAKRTKAKETSGSGSEDEKPKKKKAKKDDDE
What is the function of this protein?
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes.  The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair.  During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure.  It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II (By similarity).
What are the official names of this protein?
FACT complex subunit POB3, Facilitates chromatin transcription complex subunit POB3.
What is the protein family that this protein belongs to?
Belongs to the SSRP1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: COX2_DROME
Sequence: MSTWANLGLQDSASPLMEQLIFFHDHALLILVMITVLVGYLMFMLFFNNYVNRFLLHGQLIEMIWTILPAIILLFIALPSLRLLYLLDEINEPSVTLKSIGHQWYWSYEYSDFNNIEFDSYMIPTNELMTDGFRLLDVDNRVVLPMNSQIRILVTAADVIHSWTVPALGVKVDGTPGRLNQTNFFINRPGLFYGQCSEICGANHSFMPIVIESVPVNYFIKWISSNNS
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YQEJ_ECOLI
Sequence: MIDYKKNLLFILVFISGFILFTVYSYTAEKMIYNETCTANWVIFNDQGRANLTIDFMYNKKNKTGTVALSGTWQQGNRESKSIRRNIEYTWIENYDTAHLTSKKVNKFEIMDQVDDDRLAQLIPDFYVFPEKSVSYNILKQGKHAFILSIGNRAIMHCAR
What are the official names of this protein?
Uncharacterized protein YqeJ.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: SYK_THEP3
Sequence: MSNSNDNIWNNTEELNELLRIRREKLNILRSMGIEPYGIDRFERTNLSSDIKNDYENFEGKVVTLAGRIMSKRSHGKASFADIQDRDGRIQIYVKYDTVGEKNYEIFKILDIGDIIGVTGEVFKSKTGEITIRVTDFKLLSKSLQILPEKWHGLKDPDLRYRQRYTDLIINPEVKEVFLKRTKIIKAIREFLDNRGFLEVETPILHTIAGGAAARPFITHHNALDIDMYLRIALELHLKRLIVGGLEKVYEMGRVFRNEGMDIRHNPEFTLLELYEAYTDYYGMMELTEQLFAYVAQKVNGITKIVYQGTEIDLTPPWKRITMVDAIKEYVGVDFNEVKTDEEAIEIAKKLNLETKEGMKKGEVIALVFDELVEQHLIQPTFVMDYPVEISPLAKRKHDNPAFTSRFEAFIYGREVANAFSELNDPIDQKERFLEQLKQREAGDEEAHMMDEDFINALEVGMPPTGGLGIGVDRLVMFMTDAYSIRDVILFPTMKPKND
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RFCL_METST
Sequence: MKWVEKYAPKKLGDVLGNAKAKAQIEVWANKWSKGVPQKPLLLMGPPGIGKTTIAHLVGKEYFSETIEVNASDKRSYDIIKSSIGEAAQTRSLFHSGYKLLIMDEVDGISGRDDSGGARAVNETIKNSKQPIILMANDAYSKRLTSIKPKCQGIKFTKVHTNSINAQLKRICAREDIEYDSEALYTLSKESNGDLRSAITSLEAIVDNDKKITKDSLSVIAKKDGEQNIFDTVVAVLKSKNPEHVAEAMRVNTQPPFLIELIAENIPREYERTNEIVKAYEMISLADVNLGRAFRTQNYTYWKYAFLFMGRGVAAAKKQTYKKFSRIITPTIYTKLSKSRKNRNLKEQVTQKMSLKLHTSPKELEKQLVFYEELFKDNEQAYDLKQYFKLTDDEVKLFRSRKIPASVEKKRLTKLRKEQELEEKEIQKQKIIDAKKVELKEESKNKKEIKVKTKKDTVEDSSKTKSTTKSKKTSKSTPTKKVTKTKKSSNSTTKNKTESPKNSSKTSSKTSVDDKKTSKKNNKKKSRQTTLFDF
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.
Protein: Y2836_SHESH
Sequence: MILYLHGFDATSPGNHEKMRQLQFIDKDVRLVSYSTLHPKHDMQHLLNEVSRQLQQSDDSDPIIIGVGLGAYWAERIGFLNGIRSVLINPNLNPQENMVGRIDRPEEYADIAGKCVSEFRGKNQGKALVILSRKDQVNDNQSVSEQLGGFYQICWDEEQPHKFPVLASHLPQINLFKQA
What are the official names of this protein?
UPF0227 protein Ssed_2836.
What is the protein family that this protein belongs to?
Belongs to the UPF0227 family.
Protein: RL24_SALRD
Sequence: MVMLNKTITSAKSAGEDREAGYVGKVLKVFPDEQRVIVEGVNVRVFHEKPSRSNREGGRTEREAPIHVSNVNPIDSNGESTRIGRKKVEDPDTGRSRWVRYAKTTGEELDD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: YP010_HUMAN
Sequence: MAAKSTQDSLPRDTGEPSALPVQGRAEGRSSEGRKERTAECALRGKQASEPALRKRNFLPGPNSDTVRPAAETELVPCSLRHPRQDLCGEHPSFPVMQPSLETQAKPERDRAVLIPPKGPWPPAQGLAMRTHCPTGPPSKAYCRGGSSSTSRNQVASLAYRTQNTAASQPRQPGGRGKEDTAGYGSCSPRSLAV
What are the official names of this protein?
Putative uncharacterized protein FLJ32790.
Protein: DMSC_HALSA
Sequence: MADDDTTARRPVLSSFGTLGRGWLGVLALLLVIGLGAWAYQLQHGLIETGMRNVFSWGLYIMLFVLFVGLSAGGLILSSAPKFFHSQRYEGFARLGVLVSLGCIIVAGLLILPDIGRPDRIYQFVTSPDFRSPMVWDFGIVMLYGALNVWYLWLLTRRDLAARGSRLSLWVSDSAAGRDRDRTLMFWTAVCALPAAVALHSVTGWIFATQVGRGDWFSPLVAPVFIAKALVSGLGLLLVVSILADRFTAFTADRGELTSLGKLLGIFLAFHVVYLLAAERLPHAWAHHFGFWAITSNFLIGDTVYFWLWTGLGGAVPLLLLATPSLRRRTAVIFTASVLAVFGTLFEGIRLVFTGYQRVNINAAPGIATGGEYAGLTTDAWATAGTYTPTAVEIAVTVGVISIGALIVMAGLRYLPLQRAAPDAAYATDGGDRTQ
What is the function of this protein?
Dimethyl sulfoxide (DMSO) reductase catalyzes the reduction of dimethyl sulfoxide (DMSO) to dimethyl sulfide (DMS) during anaerobic respiration; it can also use trimethylamine N-oxide (TMAO) as terminal electron acceptor.  Subunit C is proposed to be a membrane anchoring subunit.
What are the official names of this protein?
Putative dimethyl sulfoxide reductase membrane subunit C, DMSO reductase subunit C.
What is the protein family that this protein belongs to?
Belongs to the NrfD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PPAC_LACPL
Sequence: MSKELVFGHQNPDTDAIVAAKAFSYYENKMGADTEAVALGEPNEETQFVLDYFDEPALRVITKASDEVDSVMLVDHNEPQQSVSDIADVTVSHVVDHHRIAGFDTAQPLFYRAEPLGCCSTVIYKLFKENDIEIPAKLAGLMLSAIISDTLLLKSPTTTETDVAVVKDLAKIADIDYETYGLAMLKAGTNLDSKTEKELIDADAKSFEMAGKTVRVAQINTVDLDDVFKRQAALEAAAKDENASDGYDLFLILATNILDSNSELLVVGNPTEPVEKAFGKTIANNRLSLPGVVSRKKQVVPQLTDAFNA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MUKF_VIBCM
Sequence: MSEFTQDTVQKPIDELVTWVKQYDFSLNLPTERLAFLLAIAVLSNERFDEELGEGELHDAFAIVTRLFAESGEASAFRANNAINDLVKQRLLSRFTSEMTEGASIYRLTPLAIGITDYYVRHREFSKLKLSIQLSMVADEMAKAVESAQQGGSVAHWRKNVFGVLKYSVSEIFDRIDLNQRVMDEQQQSVKEQIADLLNKDWRDAINNCEALLSETSATLRELQDTLQAAGDELQTQILDIQECVYGDLELDFIEETLSALQMKLDRITSWGQQSIDLWIGYDRHVHKFIRTAIDMDQNRAFSQRLRQSMNDYFEQPWYLTYADAERLSDLRDETLTLRDEEVTGHVPTEVEYEELQQVNDELAQRIGDMLKVHKEQGAAIDLALVLRDYLASHPRTHHFDLARMVVDQAVRLGYSESDYRAIQPDWTAINDFGAKVQANVIDRY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: ISD11_SCHPO
Sequence: MSVSKQHVVRLYRNILKTSKLFPYTYREYTIRRTRDKFKELKVESDPAKFEQGIKDSEKLLEIIQRQSIINGMYNKRNLVVEGIDDTAEGEVKKSFENASQS
What is the function of this protein?
Required for mitochondrial iron-sulfur (Fe-S) protein biosynthesis.
What are the official names of this protein?
Protein isd11.
What is the protein family that this protein belongs to?
Belongs to the complex I LYR family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TCP4_RAT
Sequence: MPKSKELVSSSSSGSDSDSEVEKKLKRKKQVVPEKPVKKQKPGESSRALASSKQSSSSRDDNMFQIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL
What is the function of this protein?
General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery.  May be involved in stabilizing the multiprotein transcription complex.  Binds single-stranded DNA.  Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).
What are the official names of this protein?
Activated RNA polymerase II transcriptional coactivator p15, Positive cofactor 4, PC4, SUB1 homolog, p14.
What is the protein family that this protein belongs to?
Belongs to the transcriptional coactivator PC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL18_FRATT
Sequence: MDKKTARLSRSKRTRIKLRELGHTRLCVYRTPRHVYAQVISGDGSTVLVAASTVEKDVKAKCKYTGNVESAAIVGEIIADRCKEKGISQVAFDRSGYKYHGRVKALVEAAREHGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: RNPH_FRACC
Sequence: MIRADGRRPDELRQVTILRGWQEHAEGSALISAGRTRVLCAASVTTGVPRWRKGSGLGWVTAEYSMLPRATDTRNDRESVRGRISGRTHEISRLIGRSLRACIDLKALGENTIAIDCDVLLADGGTRTAAITGAYVALVDAARWLGRPDAIITSVSAVSVGVVKGEAMLDLAYSEDSTADTDMNVVCTGADGFVEVQGTAEGTPFDRTMLDSLLDLAVRGCAQLTAIQTEALRGPVPAGPPRPGGAR
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: CH10_CERSK
Sequence: MAFKPLHDRVLVRRVQSDEKTKGGLIIPDTAKEKPAEGEVVSCGEGARKDSGELIAMSVKAGDRVLFGKWSGTEVTIDGAELLIMKESDILGILS
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMI_HELHP
Sequence: MKTILVITDGIGYSDKTQYNAFYHAKKPTYDYLFKNVPYGMIDTFGLSVGLPQGQMGNSEVGHMCIGSGRVLYQDLVRISRAIEYDEIKDNPALVEVTQQSAVVHLCGLLSDGGVHSHIVHLKALAQILSTQGKRVYLHLITDGRDVLPKSALNYLADIESICEDNVSIASVSGRFYAMDRDKRWDRVQKAYESIALGKNPTNLSPKEYIQSQYDEGIFDEFLTPVSFGGFQGMNDDESFVFVNFRSDRAREIVDCLGNPQFKEFKRERYVKLHIATMTEYDATFPYPILFPKQNVQNTLAEVISSHRLKQFHTAETEKYAHVTFFLNGGREEAFIGEERVLIPSPNVKTYDLQPQMNASAVGDAVIKAVEQGYDFVVVNFANGDMVGHTGNLEAAIKAVEAVDKELGRIVESAQKHHYALFITSDHGNCEEMKDEKGNMLTNHTVGQVWCFGMIEGVSKIENGGLNNIAPSVLKAMNLPIPPEMDKPLF
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-independent phosphoglycerate mutase, BPG-independent PGAM, Phosphoglyceromutase, iPGM.
What is the protein family that this protein belongs to?
Belongs to the BPG-independent phosphoglycerate mutase family.
Protein: RL24_BUCAT
Sequence: MALKLRRNDSVVILTGKDKGKTGIIKNILSLNQVIVKGLNLIKKHQKPVPSQNKSGGIIEKEAPIHISNIAILNPESNKADRIGFRFEEGRKVRFFKSTGKTIQ
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.