PharMolix/UniProtQA huggingface dataset:
Protein: NDK_BARBK
Sequence: MAIERTFSMIKPDATRRNLTGAITKMLEDTGLRVIASKRVWMSRREAEGFYAVHRERPFFEELVEFMSSGPTVVQVLEGENAIMKNREVMGATNPADAEMGTIRKVHALSIGENSVHGSDSPETAKTEIAYWFSDTEIVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: REDM_ECOLX
Sequence: MQHLPAPIHHARDAVQLPVAIDYPAALALRQMSMVHDELPKYLLAPEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPFVQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNKRTGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFSMPESDAVTMLKNRHA
What is the function of this protein?
This resolvase acts at the RfsF equivalent resolution sequence of pColBM-CL139.
What are the official names of this protein?
Resolvase, Protein D.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family.
Protein: TRMD_MYCMS
Sequence: MKFSIITLFPKIINSYIEESIIKRAINKQAIKIEIIDLRNFSTLSHNQVDDYQYGGGSGMVLMIEPLIKAIESVKTTKSIVLLTTPQGKTLNQSIVKTYANNYEHIIIVCGHYEGYDERVLDYIDDEISIGDYVITGGELASLILVDSISRLLPNVIKQESHENESFENNLLDHPVYTKPYEFRNKKVPDVLLSGHHQNIKKWREEQQVIKTLKKRPDLIDITKLNRHQLEIYKKMKGEQ
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABH_NEIG2
Sequence: MQYAKISGTGSYLPANRVSNDDLAQKVDTSDEWITARTGIKFRHIAAENEKTSDLAAEAARRALADAKLNINDIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAYIKSGMAKNALVIGAETFSRIVDWNDRTTCVLFGDGAGAVVLSASDKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAVKMLSKIADDVIEEAGYTAEQIDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSAASIPLALDAGIRSGQIKRGQNLLLEGIGGGFAWGAVLLQY
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UVRC_HELP2
Sequence: MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRVQMMVKQIAFLETILVENEQDALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKKNCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKKCLEMIENKDRLIKELELKMERLSSKLRFEEALIYRDRIAKIQKIAPFTCMDLAKLYDLDIFAFYGTSNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLNACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDTSHHANSQCVGGMVVYENNAFQKNSYRLYHLKGSDEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGSFVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNLKQIALLKEKGIGEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRN
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  UvrC both incises the 5' and 3' sides of the lesion.  The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
What are the official names of this protein?
UvrABC system protein C, Protein UvrC, Excinuclease ABC subunit C.
What is the protein family that this protein belongs to?
Belongs to the UvrC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2564_MYCTU
Sequence: MGGLTISDLVVEYSSGGYAVRPIDGLSLDVAPGSLVILLGPSGCGKTTLLSCLGGILRPKSGSIKFDDVDITTLEGAALAKYRRDKVGIVFQAFNLVSSLTALENVMVPLRAAGVSRAAARKRAEDLLIRVNLGERMKHRPGDMSGGQQQRVAVARAIALDPQLILADEPTAHLDFIQVEEVLRLIRSLAQGDRVVVVATHDSRMLPLADRVLELMPAQVSPNQPPETVHVKAGEVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVLFHLPRSATVRARSDATAVGYTAQAFRERLGVTRVADLIEHRELASE
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein Rv2564.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: PXPA_THEON
Sequence: MKVDLNSDLGESFGRYKLGLDEEVMKYITSANVATGWHAGDPLVMRKTVRLAKEKGVAVGAHPGYPDLLGFGRRYMKLTPEEARNYILYQIGALHAFTKAEGMELQHVKPHGALYNALVKDEELARAVIEGITDFDRRIIFVMLSGSRPAEIAEEMGLKVAHEVFADRAYNPDGTLVLRGKPGAVIHDKELIAERVVSMVKDGGVKAINGEWIELRADTICVHGDNPKAVEIAAYIRRVLEDEGINVVPMGEFIR
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: PSBC_PORPU
Sequence: MKVFVLGWLLKINLMKTLYSQRRFYHVETPFNTNVGVGGRDIESTGFAWWSGNARLINVSGKLLGAHVAHAGIMVFWTGAMTLFEVAHFVPEKPLYEQGLILIPHLATLGWGVGPGGEIFNTYPYFVVGVVHLISSAVLGFGGLYHSLIGPDTLEESFPFFGYDWRDKNKMTTILGIHLVLLGIGAFLLVIKSLFVGGVYDTWAPGGGDVRFVSNPTLNPLVIFGYVLKSPFGGDGWIVSVNNMEDLIGGHVWIGIICIAGGIWHILTKPFAWARRAFVWSGEAYLSYSLGALSIMGLTASNFVWYNNTAYPSEFYGPTGPEASQAQAFTFLVRDQRLGANVASSQGPTGLGKYLMRSPSGEIIFGGETMRFWDLRAPWVEPLRGPNGLDLNKIKNDIQPWQERRAAEYMTHAPLGSLNSVGGVATEINSVNYVSPRSWLTTSHFFLGFFLFIGHLWHAGRARAAAAGFEKGINRENEPVLSMRPLD
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  It binds chlorophyll and helps catalyze the primary light-induced photochemical processes of PSII.  PSII is a light-driven water:plastoquinone oxidoreductase, using light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.
What are the official names of this protein?
Photosystem II CP43 reaction center protein, PSII 43 kDa protein, Protein CP-43.
What is the protein family that this protein belongs to?
Belongs to the PsbB/PsbC family. PsbC subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: SCC4_NEMVE
Sequence: MAVILSVDPCYAGLVGLAEGFRTSNPPRIRECIQCLQAILQFNPPPATQAKTHLQIGRILQQYTKNDDLARRTLEKAVSAELGHGYEEISFEASSILSLVYKDQGQYPLAKQVLRQALEITSGENLYFWQFRLFFQLAEVHACDNEFTASVEVLEMGERIAEQCGSQYMRYNIRHSHNCIIIVLLIMKDVNRVSNILMSTGSFLERWQGQSYQRESLVVFHLLLRVWQLLSVGQAKTVRPYLKQLQQSIQNLTTMTFEGMQPGPNVYEAEKFEWLPREHLCVLVYLVTVMHSMYAGYMDKVLKYSAKALNQVERLKVTSPSALVSVFQLMLLEHTIMCRVVQGQPAHAIKEISQVYQTLKHENCLVRAHKPILHTLLGLYAMSMNLMEQATTHFNIAFKTADNPVLANFVGLNLSIIYIRAGESKQIELSSVMSSIHPSNMATNSHSLQAGYYYVCALRAFFQTRIQDAKKYLRESLKIANAEDLNRLTACSLVLLGHTFLASGNPQEALNMVLPATQLSGKIPDNYIQLWAAGLLRDLYGMLGQPVQASESFHKHHSITKQLIENHMQARKLPEHGLTEWTGAVSPTKSSTIPPQQSFQTWSQPGPSRLS
What is the function of this protein?
Required for association of the cohesin complex with chromatin during interphase.  Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity).
What are the official names of this protein?
MAU2 chromatid cohesion factor homolog, Cohesin loading complex subunit SCC4 homolog.
What is the protein family that this protein belongs to?
Belongs to the SCC4/mau-2 family.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Note=Binds to chromatin from the end of mitosis until prophase.
Protein: ALB1_DEBHA
Sequence: MPSRNSINKPKDKLQRNSHASSIGKKRSARARNGIVTKSSTPRYETDSNAAPKATESKAIALYNGATTPTGVIINNTLSNKRSKKIARNKKYIAKRNEKLNIDLLADQEQMEVDEETEKEEQTKAKNQTKLDKIKEVLWAAVEDRVSEGLKVSSGTDGNGTTLGVQAF
What is the function of this protein?
Involved in proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.  Accompanies the pre-60S particles to the cytoplasm (By similarity).
What are the official names of this protein?
Ribosome biogenesis protein ALB1.
What is the protein family that this protein belongs to?
Belongs to the ALB1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PFKA_LISIN
Sequence: MKRIAILTSGGDAPGMNAATRAVVRKAIYEGLEVYGINYGFLGLVNGDIRKLELGSVGDLLHRGGTFLYSARYPEFATEEGQLKGIEQLKKHQIDGLVVIGGDGSYHGAEALTKRGFPTIGIPGTIDNDISGTDFTIGFDTALNTVLDALDKIRDTATSHERTFIIEVMGRDAGDIALWSGLAGGAEAIIVPEESFNMDDVVDRLNKGRERGKKHSIIVVAEGVMSGNEFAKQLAEYGDYHARVTVLGHVQRGGSPTAFDRVLASRLGARSVELLLENRGGLAVGIRENRIVENNIGEILKEKHTLDQKLFDLASILSI
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCIB_HAES1
Sequence: MKQLLEFIPLILFFAVYKLQGIQAAAITLIIATLIQLMILKLKYGKIEKQQLIMGSAVVFFGSLSAYFNELEFLKWKVTVVYALFSLILLVSQYGFKKPLIQQLLGKEIQLPTYVWHNLNLGWAVFFLLCMLINLYISQYLSDDIWVDFKTFGILGMTLIATLVTGVYIYRYLPKSEQE
What is the function of this protein?
Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.
What are the official names of this protein?
Inner membrane-spanning protein YciB.
What is the protein family that this protein belongs to?
Belongs to the YciB family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: E2F1_DROME
Sequence: MSKFFVNVAPINNSNSSSSHTTTSSNTQRHQQHQQHYGGSGTTGHTMVARRLNYDLHGGTTSINNNNNIVIKNESVDLDYDHVLSSSDSNSNGGVAAHLRDHVYISLDKGHNTGAVATAAAAATAGHTQQQLQQQHHHQNQQQRKATGKSNDITNYYKVKRRPHAVSDEIHPKKQAKQSAHHQTVYQKHTASSAPQQLRHSHHQLRHDADAELDEDVVERVAKPASHHPFSLSTPQQQLAASVASSSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWRCGQSMVSQERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVLPNTKLPREIYVKAENSGEINVFLCHDTSPENSPIAPGAGYVGAPGAGCVRTATSTRLHPLTNQRLNDPLFNNIDAMSTKGLFQTPYRSARNLSKSIEEAAKQSQPEYNNICDIAMGQHHNLNQQQQQQQQQLLQQPEEDDVDVELNQLVPTLTNPVVRTHQFQQHQQPSIQELFSSLTESSPPTPTKRRREAAAAAIAAGSSTTATTTLNSHNNRNHSNHSNHSNHSSSNNSKSQPPTIGYGSSQRRSDVPMYNCAMEGATTTSATADTTAATSRSAAASSLQMQFAAVAESNNGSSSGGGGGGGGYGSIAGAGANADPHQPYSHDRNSLPPGVADCDANSNSSSVTLQGLDALFNDIGSDYFSNDIAFVSINPPDDNDYPYALNANEGIDRLFDFGSDAYGP
What is the function of this protein?
Transcriptional activator that binds to E2f sites.  Required for wild-type growth in mitotic and polytene tissues, Contributes to the expression of replication genes at the G1-S transition and Cyclin E.  Activates cell proliferation in wing imaginal disk, which requires expression of vg.
What are the official names of this protein?
Transcription factor E2f1, dE2F.
What is the protein family that this protein belongs to?
Belongs to the E2F/DP family.
What are the subcellular locations of this protein?
Nucleus.
Protein: IPI1_SCLS1
Sequence: MGSSARKKKEKKKDFQKTKLRVGKTKAKADNFTDTSFKSKSIVVNQQSLTTSAPSNVVQFTHYLSLASSSKSDTQRKDALSFLTTQLSSQPVNEAIPLPTAVILPKLLPLILDGNASVRSQLLKFLRLLPPADIGDRVESALLYTRAGMTHLATEIRVDALAVLEWLLQVAGDDVVSCPGGWVKTLKSFMSMIGWTTSSATSKWSSASRVSFGISRASFEKSGKTLPRQLLVLSQFLKAGLVEPDTAAQPTTSDNHFPLFDVERHMIPSRANAYAHLNLFGSSRDEEGEMYIDREDRQRVFHKRFQADVVTGVEHAKREAGEAGRAAAVLTKVLRDGMNDYSGVDDTQ
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein ipi1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RPOB_CAUVN
Sequence: MAQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQRETRPGLRRDEGVEAVFKSVFPIKDFNERAVLEYVSYEFEEPKYDVEECIQRDMTFAAPLKVKLRLIVFETEEETGARSVKDIKEQDVYMGDIPLMTDKGTFIVNGTERVIVSQMHRSPGVFFDHDKGKTHASGKLLFAARVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLYALGMDGEEILTTFYDVVPFEKRSGGWATPYKPERWRGVKPEFPLVDADTGEEVAPAGTKITARQAKKFADGGLKTLLLAPEALTGRYLARDAVNMATGEIYAEAGDELDVTSIQALADQGFSTIDVLDIDHVTVGAYMRNTLRVDKNAIREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDAERYDLSSVGRVKMNMRLEQDVSDEVRILRKEDVLAVLKVLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRMERAIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATHARVNKYGFIESPYRRVKDGKPQDEVVYMSAMEESKHVIAQSNIKVAEGEIVEDLVPGRINGEPTLLQKETVDLMDVSPRQVVSVAAALIPFLENDDANRALMGSNMQRQAVPLVQSDAPLVGTGMEAVVARDSGAVVIAKRTGVVEQIDGTRIVIRATEETDPARSGVDIYRMSKFQRSNQSTCINQRPLVKVGDRIVAGDIIADGPSTELGELALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIGAEVQPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVAGTIVDVRVFNRHGVDKDERALAIERAEIDRLGKDRDDEFAILNRNISGRLKELLIGKVALSGPKGLSRGEITAEGLAQVASGLWWQIALEDEKAMGELESLRRLFDENRKRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISRILPIEDMPFLADGTHVDVVLNPLGVPSRMNVGQIFETHLGWACANLGKQITNLLEDWQQGGQKQALVERLTEIYGPDEELPDTEEGLVELARNLGKGVPIATPVFDGARMDDIEGHLEMAGVNKSGQSILFDGLTGEQFKRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: CYSH_BACMK
Sequence: MLTYETWKENSVSFSEEDETKGALSVLSWAYNEYKDEIVYACSFGVEGMVLLHLINQVNPSAKVVFLDTNVHFQETYELIKKVRERFPSLNIIEKQPELTLDEQAKLHGEKLWESNPNLCCSIRKILPLEKSLAAEKAWISGLRREQSETRKHTQFINQDRRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGDGGNSRDGRWAGKMKTECGLHFQ
What is the function of this protein?
Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.
What are the official names of this protein?
Adenosine 5'-phosphosulfate reductase, APS reductase, 5'-adenylylsulfate reductase, Thioredoxin-dependent 5'-adenylylsulfate reductase.
What is the protein family that this protein belongs to?
Belongs to the PAPS reductase family. CysH subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GSA_ROSCS
Sequence: MKTYRSESLFAEARSLFPGGVNSPVRAFRAVGGAPRFIARGEGAFLVDVDGNRYIDYVLSWGPLILGHAHPNVVAAIAEQAAHGTSFGAPTELESELARLITQAMPSVEMVRFVSSGTEAAMSALRLARAATRRDKVIKFAGCYHGHFDGFLVQAGSGVATLGLPDSPGVTAATAASTLTAPYNDLDAVESLLKANPGEVAAIAVEPVAGNMGLVLPQPGFLEGLRRLADEHGALLIFDEVMTGFRVGYGGAQGKYGITPDLTCLGKVIGGGLPAAAYGGRRDLMELIAPAGPVYQAGTLSGNPLAMAAGAATLRAIRAPGVFEQLERAAAMLCSGFEHAAAEADIALRTAYAGSMWGFFFTDEPVVDYVSAKKSDTQRYAQFFHAMLERGIYLAPAQFEASFVSLAHSDALIQETIAAAADALRSIQNAARKG
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARPC4_BOVIN
Sequence: MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF
What is the function of this protein?
Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF).  The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility.  In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA.  The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
What are the official names of this protein?
Actin-related protein 2/3 complex subunit 4, Arp2/3 complex 20 kDa subunit, p20-ARC.
What is the protein family that this protein belongs to?
Belongs to the ARPC4 family.
Protein: GGT_PSEUA
Sequence: MKNQTFSKALLATALSCALFNVHAASQAPVGAENGMVVTAQHIASKVGVEVLKSGGNAIDAAVAVGYALAVVYPAAGNIGGGGFMTIQLADGRKTFLDFREKAPLAATANMYLDKDGNVIKGASTTGYLAVGVPGTVSGMEYAREKYGTKTRQQLISPAITLADKGFVLEQGDVDMLWTSTKDFEKDRANSGAIFMNKGQPFQPGERLVQKDLARTLRLISAKGTDGFYKGEVADKLVASMKAGGGIITQADLDQYKTRELAPVECDYRGYHVVSAPPPSSGGVVICEIMNILEGYPMKELGYHSAQGVHYTIEAMRHAYVDRNSYLGDPDFVKNPLAHLLDKDYAAKIRAAINPQKAGISQEIKPGVPPHEGSNTTHYSIVDKDGNAVSVTYTLNDWFGAKVMANGTGVLLNDEMDDFTSKVGVPNMYGLIQGEANAIGPGRRPLSSMSPTIVTKDGKTVMVVGTPGGSRIITATLLTMLNMIDYGMNLQEAVDAPRFHQQWMPESTNIEAFALSPDTQKILESWGQKFAGPQPANHIAAILVGAPSLGGKPIGKNRFYGANDPRRNTGLALGY
What are the official names of this protein?
Glutathione hydrolase proenzyme, Gamma-glutamyltranspeptidase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyltransferase family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL5_BORBR
Sequence: MSRLQEFYKSKVVADLQAKFGYKCVMEVPRITKITLNMGVSEAVADKKVIEHAVSDLTKISGQKPVVTKTRKAIAGFKIRENYPIGCMVTLRGQRMYEFLDRLVAVALPRVRDFRGISGRAFDGRGNYNIGVKEQIIFPEIEYDKIDALRGLNISITTTAKTDDEAKALLTAFSFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RS24_SULIA
Sequence: MESQAKVKISDKAEGIIERDVQNAVIGRREISLKVYHMGSGTPSRKDIIKAIIQAFASQENLVVVRKISTSYGAGISNVKLHIYKSREILEKIEPKYLLDRDAGTKQKKGGSKGGQGAKG
What are the official names of this protein?
30S ribosomal protein S24e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS24 family.
Protein: PETN_PROM4
Sequence: MLFTFAWASLAAIFTFSIAMVVWGRNGDGTIDF
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.
What are the official names of this protein?
Cytochrome b6-f complex subunit 8, Cytochrome b6-f complex subunit PetN, Cytochrome b6-f complex subunit VIII.
What is the protein family that this protein belongs to?
Belongs to the PetN family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Single-pass membrane protein.
Protein: RS3_THEGJ
Sequence: MAIERYFIKEGVKEMLIDEYLEKELRRAGYGGIDIKKTPLGTKVIIFAASPGYVIGRGGRRIRELTRILERQFGLENPQIEVEEIKNPYLNAKVQAVRLAQALERGIHFRRAAYSAIRAIMRNGARGVEIRLSGKLTGERAKSVRFYQGYLAKVGNPAETLVSKGYAQALLKLGVIGVKVAIMPPDARLPDEIEVKEIVEEEVSGNEAQ
What is the function of this protein?
Binds the lower part of the 30S subunit head.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: MT1_COLGL
Sequence: MSGCGCASTGTCHCGKDCTCAGCPHK
What are the official names of this protein?
Metallothionein-like protein CAP3.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 8 family.
Protein: RS11_CLOP1
Sequence: MAAQKVKKTRRRKERKNVEHGAAHIQSTFNNSIVTLTDAKGNALAWASAGGLGFKGSRKSTPFAAQMAAETAAKAAMEHGLKSVEVYVKGPGAGREAAIRSLQAAGLEVTLIKDVTPIPHNGCRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: RUVC_RICCN
Sequence: MIILGIDPALGSLGWAVVAKETAQLKYLASGIIRTNSKDAIHHRLAFINSTLEKVILEYQPNMVAIEETFVNTNSVTSLKLGYARGAIMSLIGRYNLDMREFKPNTVKKTVTGYGHAEKDQMLHMIKLLLSGTALITNSDEADAVAIAYTCLVTKNY
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: YBJQ_ECO27
Sequence: MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTAVKTRR
What are the official names of this protein?
UPF0145 protein YbjQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: UBE3B_HUMAN
Sequence: MFTLSQTSRAWFIDRARQAREERLVQKERERAAVVIQAHVRSFLCRSRLQRDIRREIDDFFKADDPESTKRSALCIFKIARKLLFLFRIKEDNERFEKLCRSILSSMDAENEPKVWYVSLACSKDLTLLWIQQIKNILWYCCDFLKQLKPEILQDSRLITLYLTMLVTFTDTSTWKILRGKGESLRPAMNHICANIMGHLNQHGFYSVLQILLTRGLARPRPCLSKGTLTAAFSLALRPVIAAQFSDNLIRPFLIHIMSVPALVTHLSTVTPERLTVLESHDMLRKFIIFLRDQDRCRDVCESLEGCHTLCLMGNLLHLGSLSPRVLEEETDGFVSLLTQTLCYCRKYVSQKKSNLTHWHPVLGWFSQSVDYGLNESMHLITKQLQFLWGVPLIRIFFCDILSKKLLESQEPAHAQPASPQNVLPVKSLLKRAFQKSASVRNILRPVGGKRVDSAEVQKVCNICVLYQTSLTTLTQIRLQILTGLTYLDDLLPKLWAFICELGPHGGLKLFLECLNNDTEESKQLLAMLMLFCDCSRHLITILDDIEVYEEQISFKLEELVTISSFLNSFVFKMIWDGIVENAKGETLELFQSVHGWLMVLYERDCRRRFTPEDHWLRKDLKPSVLFQELDRDRKRAQLILQYIPHVIPHKNRVLLFRTMVTKEKEKLGLVETSSASPHVTHITIRRSRMLEDGYEQLRQLSQHAMKGVIRVKFVNDLGVDEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEFVGKMLGKAVYEGIVVDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSIKRYDGDITDLGLTLSYDEDVMGQLVCHELIPGGKTIPVTNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDNAEIDLEDLKKHTVYYGGFHGSHRVIIWLWDILASDFTPDERAMFLKFVTSCSRPPLLGFAYLKPPFSIRCVEVSDDQDTGDTLGSVLRGFFTIRKREPGGRLPTSSTCFNLLKLPNYSKKSVLREKLRYAISMNTGFELS
What is the function of this protein?
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
What are the official names of this protein?
Ubiquitin-protein ligase E3B, HECT-type ubiquitin transferase E3B.
Protein: RL29_BURP6
Sequence: MKASELLQKDQAALNKELSDLLKAQFGLRMQLATQQLTNTSQLKKVRRDIARVRTVLTQKANQK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.