PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_MYCPN
Sequence: MKLQIKPPNNFAEFVGKQEIINQIQLSIKASRINKAQLDHILLYGPPGVGKTTLARLIASEMNTKLQIIQGGHLQRPSDFLNAVSLIKKGDVLFVDEIHAVAPSVMELMFPVMDDFRVQVLIGKDFNSKMVEMKVNPFTWIGATTQFGKIINPLEDRFGMILNIDYYSNQEIERIVSIYGEQMELELKPEEITQITQHSKQTPRIAIRIVKRLFEQKIVNKKIDLAALFKSLMIYKNGLQSIDVQYLKALNGQYEPQGIKSICSMLGIDKSTVENKIEPFLLRENMIQKTKKGRIITRTGRNYLTSC
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: GPSB_STAAS
Sequence: MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQKMADMNNEVVKLSEENHKLKKELEELRLRVATSRPQDNKSFSSNNTTTNTSSNNVDILKRISNLEKAVFGK
What is the function of this protein?
Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome.  Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression.  Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed.  Also contributes to the recruitment of PBP1 to the division complex.  Not essential for septum formation.
What are the official names of this protein?
Cell cycle protein GpsB, Guiding PBP1-shuttling protein.
What is the protein family that this protein belongs to?
Belongs to the GpsB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Shuttles between the lateral wall and the division site in a cell cycle-dependent manner.
Protein: UTP18_SCHPO
Sequence: MEKDTEELELENAVFGNINNFSSFLDKENETFDVMMNEAPELSEDNDAQEDELEKLEDAELFMFDTGSADGAKDSVPLDIIAGDNTVKEDEEASNEIPSIWEDSDDERLMISLQDHSRLRKLRQYEDEDMVNGLQYARRLRTQFERVYPVPEWAKKQDVTEEEDEFNALSEKSVIPKSLKSLFKSSVSYINQSSKLLAPGTINIKRLKDANFQAPSHSGIRCMSIHPYFPLLLTCGFDRTLRIYQLDGKVNPLVTSLHLRSSALQTALFHPDGKRVIAAGRRKYMYIWDLESAQVQKVSRMYGQENFQPSMERFHVDPTGKYIALEGRSGHINLLHALTGQFATSFKIEGVLSDVLFTSDGSEMLVLSYGAEVWHFNVEQRSVVRRWQVQDGVSTTHFCLDPSNKYLAIGSKSGIVNIYDLQTSNADAAPKPVTTLDNITFSINSMSFSQDSQVLAIASRGKKDTLRLVHVPSFSVFRNWPTSATPLGRVTCLAFGKGGELCVGNEAGRVGLWKLAHYD
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.
What are the official names of this protein?
Probable U3 small nucleolar RNA-associated protein 18, U3 snoRNA-associated protein 18.
What is the protein family that this protein belongs to?
Belongs to the WD repeat UTP18 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TYSY2_BACAM
Sequence: MKQYKDLCRHVLENGEKKGDRTGTGTISTFGYQMRFNLQGGFPMLTTKKLHFKSIAHELLWFLKGDTNVRYLQENGVRIWNEWADENGELGPVYGSQWRSWRGADGETIDQISRLIHDIKTNPNSRRLIVSAWNVGEIDRMALPPCHCLFQFYVADGKLSCQLYQRSADVFLGVPFNIASYALLTMMIAHVTGLEPGEFVHTFGDVHIYQNHVEQVNLQLTRDVRPLPKLRFARNVDSIFDFAFEDFIIEDYDPHPHIKGAVSV
What is the function of this protein?
Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product.  This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
What are the official names of this protein?
Thymidylate synthase 2, TS 2, TSase 2, Thymidylate synthase B, TS B, TSase B.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_BIFLD
Sequence: MTRLRIDLAYDGGGFYGWAKQPNLRTVQGTIEDALHKVLRVPTDDAAEPLRLTVAGRTDTGVHASHQVAHLDVSDEVLNRCVGHMTIPVTEALTRRLKAVLPSDIVIHGIAVAPVGFDARFSALERTYVYRVADRSSEVDPRLRGCVLTVDEALDLELMNRAASLTIGLHDFGSFATPNPGGTTIREVKTAYWRRVPITPLVPDEMASHEAYRTPSLESGLVVFTIVADAFARNMVRSLVGSCIKVGSGRKSLEWFAGKMAEPVREGSSGPIAPQGLTLEHIAYPADDQLAARAEAIRAVRTL
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: GLP1_CITSI
Sequence: TDPGHLQDVXVAINDPKXGVFVNRK
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: ALL13_CARMA
Sequence: EYDDMYTEKRPKVYAFGL
What is the function of this protein?
May act as a neurotransmitter or neuromodulator.
What are the official names of this protein?
Carcinustatin-13.
What is the protein family that this protein belongs to?
Belongs to the allatostatin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GPDA_BACCN
Sequence: MTKITVIGAGSWGTALAMVLADNGHDVRIWGNRPELMDEINTKHENKRYLPGITLPSTIVAYSSLEEALVDVSTVLLVVPTKAYREVLQDMKKVISGPMTWIHASKGIEPGTSKRISEMIEEEIPEHLIRDVVVLSGPSHAEEVALRQATTVTSAAKRMEAAEEVQDLFMNHYFRVYTNPDIIGVELGGALKNIIALAAGITDGLGLGDNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTGMGDLIVTCTSVHSRNWRAGNMLGKGHSLEEVLDSMGMVVEGVRTTKAAYELAEKMEVEMPITAALYDVLFNGKNVKDAVGSLMGRVRKHEVEAIPDLSR
What are the official names of this protein?
Glycerol-3-phosphate dehydrogenase [NAD(P)+], NAD(P)H-dependent glycerol-3-phosphate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HN_NDVK
Sequence: MDRAVSQVALENDEREAKNTWRLIFRIAILLLTVVTLATSVASLVYSMGASTPSDLVGIPTRISRAEEKITSALGSNQDVVDRIYKQVALESPLALLNTETTIMNAITSLSYQINGAANNSGWGAPIHDPDFIGGIGKELIVDNASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHSHSHQYLALGVLRTTATGRIFFSTLRSISLDDTQNRKSCSVSATPLGCDMLCSKVTETEEEDYNSAVPTLMAHGRLGFDGQYHEKDLDVTTLFEDWVANYPGVGGGSFIDGRVWFSVYGGLKPNSPSDTVQEGKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRIQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRILTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFNAFTRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHTLRGVFGTMLDSEQARLNPASAVFDSTSRSRITRVSSSSTKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKNDGVREARSG
What is the function of this protein?
Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins.
What are the official names of this protein?
Hemagglutinin-neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the paramyxoviruses hemagglutinin-neuraminidase family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein.
Protein: YP177_YEAST
Sequence: MSSDVAGVKKSSSSSSSTSSPFMFSMLLMFSRSISSTIKISANRILLCCTSSFSTTSGFFKIESNRLTSRSSSGIFSRTACNRSCGNCFSISAVLSFCVAPLCCKSTGRFSSAIYLLIFRSTR
What are the official names of this protein?
Putative uncharacterized protein YPR177C.
Protein: Y657_HAES1
Sequence: MNGRLLEIVACPICQGRLKYDSENEQLICHFDHIAYPIKQGIPILLSDQAISLSTSLTNPEQQNQ
What are the official names of this protein?
UPF0434 protein HS_0657.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: ACP1_CAEBR
Sequence: MRVLFYVFPFVIFALSQAQLISVHVIFRHGARAPVLNVTSEEAKSYFYRGLGQLTDVCIEQAKLIGKVLKDRYVNTFVDARMLPTQLLFRSSPVERCLMTIQTVGNTMFVNSTPPVQTVAKPDDFLLVPKLDCAFQIDEWTNFFNLTENDKKQAKKNPWFISEKALRRATAASQTLQQRSDENLPALILEKDAGLAVPSWFNEEAYKESLTVFYKALAVMSSVGEYKSSKGIRVKTGLLLDKILNDIQEKVRCHEKNQKGHISCDRHKLQVFSTHDLLILPFLDALGIREAALGEDLPPKFLSAIIIETMLLDDIPFVKVFYRGDPRDITLRDMTGLVRNCPPNQALCPVNLFTSCCGEFITADPRRECYEEKADQQLHNWTMTTVSWILIGISAFLLIILIIMSYLAVRYKNRSVVTIKKVCLEN
What are the official names of this protein?
Putative acid phosphatase 1.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PEPT_SALEP
Sequence: MDKLLERFLHYVSLDTQSKSGVRQVPSTEGQWKLLRLLKQQLEEMGLVNITLSEKGTLMATLPANVEGDIPAIGFISHVDTSPDFSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGVAEIMTALAVLKGNPIPHGEIKVAFTPDEEVGKGAKHFDVEAFGAQWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGTAKGVMVNALSLAARIHAEVPADETPETTEGYEGFYHLASMKGTVDRAEMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCHITPEMKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEKAVQVIVRIAELTAKRGQ
What is the function of this protein?
Cleaves the N-terminal amino acid of tripeptides.
What are the official names of this protein?
Peptidase T, Aminotripeptidase, Tripeptidase, Tripeptide aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMSD_ECOLI
Sequence: MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWETQWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWSTRFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR
What is the function of this protein?
Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system.  May be part of a chaperone cascade complex that facilitates a folding-maturation pathway for the substrate protein.
What are the official names of this protein?
Tat proofreading chaperone DmsD, DMSO reductase maturation protein, Twin-arginine leader-binding protein DmsD.
What is the protein family that this protein belongs to?
Belongs to the TorD/DmsD family. DmsD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein. Cytoplasm. Note=Mainly cytoplasmic under aerobic conditions, and found in the inner membrane under anaerobic conditions.
Protein: RS7_BACMK
Sequence: MPRKGPVAKRDVLPDPMYNSKLVTRLINKMMVDGKKGKSQTILYNAFEIVRERSDKEPMEVFEQALKNIMPVLEVRARRVGGANYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEERLAYEILDASNNAGAAVKKREDTHKMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SYGB_SHIFL
Sequence: MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRPVHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKAVSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRLNRLTMLEKLRELFLRVADISLLQ
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VATB_PYRAE
Sequence: MLTPVVSYTTVREVKGPLIVIEKTRGVSYGEVGEVIGPDGEPRRVQVIEVGTDYAVAQVLGGTLGLPAKGSTVRFYGKTLKIPVSEQLIGRILDGKGQPRDHMPLPPPEDFRDVNGEPLNPYSREYPEEPIETGISAIDGLYTLVRGQKLPIFSGTGLPHNLMAAQVVRQATVRGSEEEFAVVFVGVGIKTEEALFFMDEFRKTGALRRAVAVLNLASDPVAERILAPRVGLTIGEYLAWQLGYHVLVVITDMTNYCEGLRELSSGRGELPGRRGYPGYMYTDLATIYERAGRARGRRGSVTQFPILTMPHDDITHPIPDLTGYITEGQLVLSRAMWGKGIYPPFDVIMSLSRLAKDAIGEGKTREDHKDVANTLIAAYSKALEIRNLATLVGERNLGWRERRYLRFADAFEQRFIKQGYYERRSFEETLDIGWDVLSILPEDELTNARPQITQKFYRRHIFESVQL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The archaeal beta chain is a regulatory subunit.
What are the official names of this protein?
V-type ATP synthase beta chain, V-ATPase subunit B.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RS12_STAAE
Sequence: MPTINQLVRKPRQSKIKKSDSPALNKGFNSKKKKFTDLNSPQKRGVCTRVGTMTPKKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: LEPA_WOLPP
Sequence: MNNIRNFAIIAHIDHGKSTLADRLIEECNGLETREMTNQVLDSMDIERERGITIKAQTVRLNYTANNGNKYCLNLMDTPGHVDFSYEVSRSLAACEGSLLVVDSSQGVEAQTLANVYKAIDNNHEIIVVLNKVDLPAADPERIKLQIEEVIGIDATESILISAKTGLGIKDVLEAIVTKLPAPQGDTNAPLQAILVDSWYDPYLGVVILVRVKNGVLKKGMRIVMMSNNATYQVDNIGIFTPKKVMTGELSAGEVGFITASMKEVADCKVGDTITEEKRPCSKALPGFKEVHPVVFCSIFPNNTDDFKYLREALEKLHLNDASFTFDAETSNALGYGFRCGFLGMLHLEVIQERLEREFDLDLTATAPSVIYKVETQNGKVLNIHNPSDMPDPTKIEIVEEPWITATIMVPDQYLGEILSLCEERRGEQQDLSYVGNTTTALLKYKLPLSEVVFDFYDRLKSISKGYASLDWEISDYQESQIDKLSFLVNGEPVDALACIVHKSRAEKRGREICARLKDLIPRQQYKIAIQAAVGGKIIARETINPYRKDVTAKLYGGDVTRRMKLLEKQKKGKKRLHSVGNINIPQNAFIEALKIND
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: NU4LC_BRADI
Sequence: MMFEHVLFLSVYLFSIGIYGLITSRNMVRALICLELILNSINLNLVTFSDLFDSRQLKGDIFAIFVIALAAAEAAIGLSILSSIHRNRKSTRINQSNFLNN
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic, NAD(P)H dehydrogenase subunit 4L, NADH-plastoquinone oxidoreductase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: YUAL_ECOLI
Sequence: MLHSDQGVQYKSNKYKILLCRYEAMQSMSRRGNYLDNSPMGRVFRRFKSKWLAKGGYGDFSHAVRDIKQ
What are the official names of this protein?
Uncharacterized protein YuaL.
Protein: LPXD2_FRATH
Sequence: MYSLDFLASKLDGEVKGDKNVEIKKIATLSQAGEGDISFCTNPKYLKALSETKASAVLITEEVLEFCNTNAVVLSNPYMALAKVMELFDKSPRPDGKIHSKAVIAASAIIGENVTIGANAVVGENVVIGDNVYIGACATIDNGTKIGNDTLIKSNVSIAHDVVIGTGCIIHQNAVIGCDGFGNARDEDGSWTKIPQLGRVIIEDDVEIGSGTTVDRGAIDDTIIKKGARIDNLVQIAHNVVIGRNTALAGVTAVAGSTTIGDNCLIGGQSAITGHISICDNTIIGGASNIGKSITKPGMYYAAFEAKPRIQWGRFVAKLAKIDTLITKVKQLEEKIK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-acylglucosamine N-acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
Protein: PRMA_SINFN
Sequence: MSEIRLFVTTTEKQAAAILDVMSVNFEEEGYAVATMEIDEKRDVWEASVYMMADEEESVKSRLADALAADFSHLPIEREVLPEIDWIAKSLEGLAPVRAGRFVVHGSHDRDKVKTGEIAIEIDAGQAFGTGHHGTTAGCLEMLACVARSRRVRNVLDLGTGSGVLAIAAWKLLHVPGLATDIDPVATRVASDNARRNGVVDGLTFATAPGFHSTAFGTHGPFDLVIANILARPLMKMAPELVAHIAPGGSVILSGILAEQRWKVLAAYNGQRLKHVQTIWKNGWVTIHLTK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPOL_ADECT
Sequence: MSLVQGHGTSGLFTEPPNPINQQESSGPSLPAQDAAQAFASSPRAGATSTIVNPPKRKYKGAVVVQRATLSISAVLDNGQCVEIKYHSNLASALTNLCNTNLYDLPACLNRPITAHNLPALIEEAAAPYSLICYYQRGTVRRVEFQAEVPLLSFPLKFLVKQGKVFLIKDISQMQKCEFCGSFFKVTHTCALRRRDFYFHHVAAHSADWWEKISFTPIGAPPNTERLFIVYDVETYTWHGKFGKQLVPFMLVFQLLGDDHLVNVAKTLATEQNWEIWNGKEQDTLYYCITPEKRAIGVKFKKFRDTLQQHIAASLWSHVICQNPQLQEKATTLGLESPEELTPDQLKKFKLKGNPRFIEVYAVGHNITGFDEILLAAQVVSTRAEIPPVFEICRNFMPRAGRLLFNDITYSLPNPSYVPAKSYEHWEQGQVLASDLKSQYIKFMVRDTFSLTHTSLKNAAKAYSLTVSKGCCPYQAVNEFYMLGSYQQDADGFPDLKYWKDQEEYSFNKDLWIKEKKGAYDIIQQTLDYCALDVQVTAQLVNKLIESYQIFIKNSVNLPETSFNVFQRPTISSNSHAIFKQILYKAEKPNTHHLSTILMAPSNEMYEYVRLSIRGGRCYPTYIGVLQEPVFVYDICGMYASALTHPFPAGSPLNPYERALAIKAYEQKMLNHKTISYFDKDLLPGIFTIDADPPAEEFLDVLPPFCSRKGGRLCWTNEPLRGEIATSIDVITLHNRGWKVTLIPDTRTTVFPEWKCLAREYVQLNISAKEEADKSKNQTMRSIAKLLSNALYGSFATKLDNKKTVFSDQIESNIAKEIASGAYVVKSSSYIETDNLCAEIMPEFVVAYPPVNSDVRQLAPPSCSEEDPTKDPLAEAPFMHNFSMTSYHYKPIMFIDAEDDDFCLHTLEKSTPLIANNRYPSQIASFVLAWTRAFVSEWSQFLYENDAGTPLENRVLKSVYGDTDSLFTTMEGYKLMEEKGKKRLKKNGGKLVFDPSNPELTWLVECETQCEKCGSDAYSSESVYLAPKLYALKDTTCPKCHHVGKGKLRAKGHATSTLSYDVLKACYYADMQQGSDVFKTSRMSLRRTLTSVQAHVQPFTVTETTLTRKLRPWKDKTLHALDMHRLIPYSRKHPNPRNTETTWMELQWMT
What is the function of this protein?
Eukaryotic-type DNA polymerase involved in viral genomic replication.  DNA synthesis is protein primed, and acts in a strand displacement replication.  Assembles in complex with viral pTP, DBP, host NFIA and host POU2F1/OCT1 on viral origin of replication.  The polymerase covalently transfers dCMP onto pTP, thereby initiating complementary strand synthesis.
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: CHAC2_MOUSE
Sequence: MWVFGYGSLIWKVDFPYQDKLVGYITNYSRRFWQGSTDHRGVPGKPGRVVTLVEDPGGSVWGVAYKLPVGKEEEVKTYLDFREKGGYRTTTVIFYPKDSTTKPFSVLLYIGTCDNPNYLGPAPLEDIAEQIFNAAGPSGRNTEYLFELADSVRKLVPEDADEHLFSLEKLVKERLEGK
What is the function of this protein?
Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide (PubMed:27913623).  Acts specifically on glutathione, but not on other gamma-glutamyl peptides (By similarity).
What are the official names of this protein?
Putative glutathione-specific gamma-glutamylcyclotransferase 2, Gamma-GCG 2, Cation transport regulator-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: PSD_NITMU
Sequence: MQTASLSVFPQYLLPKHALTLLAGRIANAEAGNLTTLLIRWFVWRYGVNMNEAINPDIRSYRTFNEFFTRPLLLENRPISDADYVCPADGVISQLGVISGDQIFQAKGHNYSAAALLGGDTRLAEKFYGGNFATLYLSPRDYHRVHMPVDARVSRMIYVPGDLFSVNAKTVRGVPGLFARNERVICIFESEFGPFALVLVGATIVGSVATVWHGVVNPRDSEGARDVQEWRYDSADLVLKKGDEMGRFQLGSTVVMLFPKNEIAFNPAWAPGRTIRFGETMATKADPAK
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: INS1_HUSDA
Sequence: HVSKAAANQHLWCGAHLVEALYLVCGERGFFYTPNKVGIVEQCCHSPCSLYDLENYCN
What is the function of this protein?
Insulin decreases blood glucose concentration.  It increases cell permeability to monosaccharides, amino acids and fatty acids.  It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver (By similarity).
What are the official names of this protein?
Insulin-1.
What is the protein family that this protein belongs to?
Belongs to the insulin family.
What are the subcellular locations of this protein?
Secreted.
Protein: AROB_ACIBY
Sequence: MQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLGKTVATCILPDGEKYKDIQHLNLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRGVYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQVVLADMAQLNTLPERELSAGLAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKEQGERALLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRANLPISCPQIPLDDFLGYMAHDKKVLNGQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_STAAS
Sequence: MRNDLETLKHIIDSSNRITFFTGAGVSVASGVPDFRSMGGLFDEISKDGLSPEYLLSRDYLEDDPEGFINFCHKRLLFVDTKPNIVHDWIAKLERNQQSLGVITQNIDGLHSDAGSQHVDELHGTLNRFYCNACHKSYTKSDVIDRTLKHCDNCGGAIRPDIVLYGEMLDQPTIIRSLNKIEHADTLVVLGSSLVVQPAAGLISNFKGDNLIIINKDRTPYDRDATLVIHDDMVSVVKSLMTE
What is the function of this protein?
NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form.
What are the official names of this protein?
NAD-dependent protein deacetylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class U subfamily.
What are the subcellular locations of this protein?
Cytoplasm.