PharMolix/UniProtQA huggingface dataset:
Protein: CLPR4_ARATH
Sequence: MEVAAATATSFTTLRARTSAIIPSSTRNLRSKPRFSSSSSLRASLSNGFLSPYTGGSISSDLCGAKLRAESLNPLNFSSSKPKRGVVTMVIPFSKGSAHEQPPPDLASYLFKNRIVYLGMSLVPSVTELILAEFLYLQYEDEEKPIYLYINSTGTTKNGEKLGYDTEAFAIYDVMGYVKPPIFTLCVGNAWGEAALLLTAGAKGNRSALPSSTIMIKQPIARFQGQATDVEIARKEIKHIKTEMVKLYSKHIGKSPEQIEADMKRPKYFSPTEAVEYGIIDKVVYNERGSQDRGVVSDLKKAQLI
What is the function of this protein?
Involved in plastid protein homeostasis.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit-related protein 4, chloroplastic, ClpR4, Protein HAPPY ON NORFLURAZON 5.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
Protein: LINC_SPHIB
Sequence: MSDLSGKTIIVTGGGSGIGRATVELLVASGANVAVADINDEAGEAVVAASGGKAAYFRCDIAQEEDVKALVAQTLAAFGGLDGAFNNAAIPQAGLPLAEVSLERFRQSMDINVTGTFLCMKYQILAMIERGTKGSIVNTASVAGVVGVPMHGEYVGAKHAVVGLTRVAAADYGKHGIRVNALVPGAVRTPMLQRAMDNDAGLEPYLNSIHPIGRFSEPHEQAQAAVWLLSDAASFVTGSCLAADGGFTAI
What is the function of this protein?
Catalyzes the dehydrogenation of 2,5-dichloro-2,5-cyclohexadiene-1,4-diol (2,5-DDOL) to 2,5-dichlorohydroquinone (2,5-DCHQ), a step in the degradation of gamma-hexachlorocyclohexane (gamma-HCH or lindane).
What are the official names of this protein?
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase, 2,5-DDOL dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: MURA_SHISS
Sequence: MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDKVSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVGEDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMHVPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRIYHIDRGYERIEDKLRALGANIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEF_PROMP
Sequence: MANNFSQLARKSKTNSPIEKVSKEQTGTPSLEIYKLGDDVLRENAKRISKVDNSIRNLAKDMLQSMYAAKGIGLAAPQIGIKKELLVIDVNFEDAAAEPLILINPEITDYGTTLNSYEEGCLSIPGVYLNVVRPSTIKLRFRDEMGRPRKMKADGLLARCIQHEMDHLNGVLFVDRVTSKEDLNKELIKEGFHQKDVIPIK
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase, PDF, Polypeptide deformylase.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: HIS4_PYRAE
Sequence: MIIPSIDIEGGRAVKRIRGQRGNYIFQGDPLELAARFRKAPLVHVVDLDGAEAGGLVNISVISKIAEILEGRCELGGGLRSLEAVERALSLCQYAVVGSLPFKNWPLFRRAAELYRDRLAVSLDYRGGEVLVGGWREKAASIAEAVRRLEEAGPYAAVIVTSVEVEGTGGGVKADIDVKSLKRIARRVFYAGGVRDCNDVERAYALGFDGVIVGYALYAGDLKKCANWY
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADI_SALCH
Sequence: MRQALPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPADAIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKALARVLVDVNKARTTRQRLTLFSRLRLRDLLPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWAEGKLAEEVMTTYVPPYKNPFTEDNNIRGTSTLADYAKLRPAFDRKHGSVTAANSTPLTDGAAAVILMTESRAKELGLRPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMADLTLFDMHEAFAAQTLANLQLLGSERFAREVLGRAQATGEVDDAKFNVLGGSIAYGHPFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, ACSs, Acetyl-CoA acyltransferase, Acyl-CoA ligase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MEND_SALRD
Sequence: MAHQSWSVLDAPNPTYLWTQLLVEELVRNGVHTFFVAPGSRSTPLTVAIARHPEAESVLHVDERGAAFAALGVGRAARGPAAWVTTSGTAVANGLPAAVEASVDGVPMLLLTADRPPELRDTGANQTIDQVKIFGDYVRWQADVPPPSDEVDPAYVLTTADQALHQTLRAPAGPVHVNCMFRKPLEPVETEASVAVPTAVDAWARGTEPYTHYPTPAPSPPGPEVDALAETVRGTEHGLVVAGRLDSAAAADATRRLATHLGWPLIPDLTSRLRRGGREQPEQVPYGDLVLTSAAFREGHPPRAVLQVGGRFASKRLRLFLRDSAPEVWAVVRPDPSRIDPDHRVTHHVEAAVPAAVDALVARLEEGPRGTTWRDDWAGASERVGAVVQAHVQESDALTDPLVAALLTEEMPSEHALVAASSMPVRDLNRHAAPGGTGGPAFANRGASGIDGTVATAAGIAEGRDGPVTLLIGDLALQHDLNGLALLQDRPVVAIVVNNDGGGIFHFLPIRKHDEFDPYFTTPHGHDFEHAAALFDLPYHRPDSPSALRSAYAQACRSGESALIEVRTDRATNRQVHDRLEASVERAVEEG
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: CLPP_LEGPL
Sequence: MPGYSDNIIRNASGLIPMVIEQTSRGERSYDIYSRLLKERIIFLLGEVEDHMANLVVAQLLFLESENPEKDISLYINSPGGVVTAGLAIYDTMQFIKPDVSTLCIGQAASAAALLLCAGADGKRFCLPNSRVMIHQPLGGYRGQATDIEIHARETLAVRERLNNIMAKHTKKTPDQIMRDTERDNFMSATQAMEYGLIDKVLYDRQIAGHSTDL
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit, Endopeptidase Clp.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM1_EHV1B
Sequence: MGSAQARQRLLAIFGQVQAYIFQVEMLKRCDPSALLPLVGSLKLNALTIRMLRRKLGGALIEQAQHQQTPLACALTMALEYAEVEGERVLRAVDDVNLAGPEGFFRATMRLDEPCEYHVRVHLDTYGGPIDAEVQFLHDAENFLKQLNYCHLITGFEAGLDALESVARFLTRTVGSGIVVPPELCDPTHPCSVCFEELCVTANQGEAVHRRLLECTCDHITRQMAVRVANIDIARHLPHALSVASERRAAAEAALRALEARRVQGHNGKSAGTEDPTQQVASRLLESHHVFKPASRCLYAVSELKFWLASTKHGDMGQPRAIDTFTENLETLDKQEKFFHLQAATVELALFGRTLDHFDRLFADQLLGLDVIDGMLVGSCAVSPDDHIEALIKACYTHHMSAPLLQRLTDPDTSNREALKQLLGRIGVDTDDGAGELGDALDVDLDNLGGAPPVNSTPCGEDALCRTVSEERPWDKLLERATADASQRRRMYAERLSKRSIASLGRCVREQRRELEKTLRVNVYGEVLLHTYVSSYNGFCARRGFCAAVSRAGTIIDNRSSTSAFDSHQFMKAALLRHPIDQSLMPSITHKFFELINGPVFDNAGHNFAQPPNTALYYSVENVGLLPHLKEELARFMITAAKGDWSISEFQRFYCFEGVTGVTATQRLAWKYIGELILAAAVFSSVFHCGEVRLLRADRTYPDSSGAQRCVSGIYITYEASCPLVAVLSAAPHGAIGAETVVIYDSDVFSLLYAVLQQLAPGSGAN
What is the function of this protein?
Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging.  Forms a tripartite terminase complex together with TRM2 and TRM3 in the host cytoplasm.  Once the complex reaches the host nucleus, it interacts with the capsid portal vertex.  This portal forms a ring in which genomic DNA is translocated into the capsid.  TRM1 carries an endonuclease activity that plays an important role for the cleavage of concatemeric viral DNA into unit length genomes.
What are the official names of this protein?
Tripartite terminase subunit 1.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae TRM1 protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=Found associated with the external surface of the viral capsid during assembly and DNA packaging, but seems absent in extracellular mature virions.
Protein: SRTD1_HUMAN
Sequence: MLSKGLKRKREEEEEKEPLAVDSWWLDPGHTAVAQAPPAVASSSLFDLSVLKLHHSLQQSEPDLRHLVLVVNTLRRIQASMAPAAALPPVPSPPAAPSVADNLLASSDAALSASMASLLEDLSHIEGLSQAPQPLADEGPPGRSIGGAAPSLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDNELWAPASEGLKPGPEDGPGKEEAPELDEAELDYLMDVLVGTQALERPPGPGR
What is the function of this protein?
Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors.  Stimulates E2F1/TFDP1 transcriptional activity.  Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
What are the official names of this protein?
SERTA domain-containing protein 1, CDK4-binding protein p34SEI1, SEI-1, p34(SEI-1), Transcriptional regulator interacting with the PHD-bromodomain 1, TRIP-Br1.
Protein: VATB1_CAEEL
Sequence: MAAVDVNQPITGHKSAIIRNYNTNPRLIYQTVCGVNGPLVILNDVKFPQFSEIVKITLPDGSKRSGQVLEISKNKAVVQVFEGTSGIDAKNTICEFTGDILRTPVSEDMLGRIFNGSGKPIDKGPPVLAEDFLDINGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSASGLPHNEIAAQIVRQGGLVQLPDRPHEQTNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRIALTSAEFLAYQCKKHVLVVLTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRDGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRLIYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIGKDVQAMKAVVGEEALSSDDLLYLEFLTKFEKNFITQGHYENRSVFESLDIGWQLLRIFPREMLKRIPESTLEKYYPRGGAKE
What is the function of this protein?
Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity).  V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (Probable).  Essential for the proper assembly and activity of V-ATPase (By similarity).  Required maternally for early embryogenesis and zygotically during morphogenesis (PubMed:22426883).  Specifically, involved in the clearance of apoptotic cell corpses in embryos (PubMed:22426883).  Also, during embryonic development, the V-ATPase is required to repress fusion of epidermal cells probably by negatively regulating eff-1-mediated cell fusion (PubMed:15866168).  In neurons, required for necrotic cell death by promoting intracellular acidification (PubMed:16005300).  Required for cell death induced by hypoxia (PubMed:16005300).  Required for acidification of synaptic vesicles and the release of neurotransmitters from adult neurons (PubMed:22426883).
What are the official names of this protein?
V-type proton ATPase subunit B 1, V-ATPase subunit B 1, Vacuolar proton pump subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
Protein: RL14_YERPE
Sequence: MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGIGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVILNNNSEQPIGTRIFGPVTRELRNEKFMKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: MTLD_BREBN
Sequence: MLAVHFGAGNIGRGFIGQLLQKAGYEIAFVDVNAALVDELNERKMYRVQLATTGKPESVVEGVRAINGQDVAAVAEAIATADLVTTAVGPNILPHIAGAIAAGITQRLTVHARPLNVIACENMIGGSEKLKEHVYEHLTESVQAQAAQWIGFPNAAVDRIVPLQQHADKLLVMVEPFFEWVVDSSQIVGEVPAIEGVTYVEDLAPYIERKLFTVNTGHAVIAYLGYQLGMKTIDEAMRDDRIVQATRGALQETGALLAAKYGFDPQVHGQYVEKILGRYTNPLLSDDIVRVARSPIRKLSQHDRLVGPALQCMEKGMNASYLGLAIAAALAFDYPEDAESARIQASLKEFGWENTLHNCTGIPAGHPLEEIVREQARRLKEWSGSH
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RSD_SALHS
Sequence: MLNQLENLTERVGGSNKLVDRWLDVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLLHAAKIWPLLEDNTQRIMDYYDTSLETAIDHDNCLEFQQALSDIGEALEARFVLEDKLIMLVFDAMHDGARVKRPA
What is the function of this protein?
Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA.  May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
What are the official names of this protein?
Regulator of sigma D.
What is the protein family that this protein belongs to?
Belongs to the Rsd/AlgQ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2AJ_BOVIN
Sequence: MSGRGKQGGKVRAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESQKTKSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.J, H2a/j.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ETV1_BOVIN
Sequence: MDGFYDQQVPYMVTNNQRGRNCNEKPTNVRKRKFINRDLAHDSEELFQDLSQLQETWLAEAQVPDNDEQFVPDYQAESLAFHGLPLKIKKEPHSPCSELGSACSQEQPFKFSYGEKCLYNVSAYDQKPQVGMRPSNPPTPSSTPVSPLHHASPNSAHTSKPDRAFPAHLPPSQPIQDSSYPMDHRFRRQLSEPCNSFPPLPTMPREGRPMYQRQMSEPNIPFPPQGFKQEYHDPVYEHNTMVGGAASQSFPPPLMIKQEPRDFAYDSEVPSCHSIYMRQEGFLTHPSRTEGCMFEKGPRQFYDDTCVVPEKFDGDIKQEPGMYREGPTYQRRGSLQLWQFLVALLDDPSNSHFIAWTGRGMEFKLIEPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPEALFSMAFPDNQRPLLKTDMERHINEEDTVPLSHFDESMAYMPEGGCCNPHPYNEGYVY
What is the function of this protein?
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' (By similarity).  Required for olfactory dopaminergic neuron differentiation; may directly activate expression of tyrosine hydroxylase (TH) (By similarity).
What are the official names of this protein?
ETS translocation variant 1.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: KEN_DROME
Sequence: MKEFQRMLMLQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSDCSTTVYFPDVNATYFKFLLDFLYSGQTCITSRDVNYLHDLLLLLQIKSDSWKTTDSAYLSSKCGGLRDRADRRKQQYTSPQNLEPDQTLKYEVDSVDESRNAADFSSAFNSNDNCESAAECERSGGHNNKEEDEDDCTHKDNKSDKDTDEIVNLSNAPPSGTSGSNSNISTSSNHQQQQHHHHHHHNHNNNNNNNNNNSSSSTINPVNLSLDLRTKSENSASRTLGSGSDHSGIDLAVTASESTKRKGLFFDSHKDVMKPLSDGSDINSSPENYVVTPHRKRRPGFHNTQSDNQPFTSYPHSLLEELRLAKSTTSPISGFGSEKNMLAHLEDGALNGDTLTPDRKHLLEAQRNRAQSPEIPMHLGPQFVYQWQSNQNAAMSAMPNLQSRLSSLSHISLNLDHPEGRSGSASGSGANLAGSNTHASSVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVITTTNGADTENRYSCCFCSMCFESVQELVRHLSGHHNNLLLTKNLRE
What is the function of this protein?
Transcription factor required for terminalia development.  Negative regulator of the JAK/STAT pathway: represses JAK/STAT-dependent expression of ventral veins lacking (vvl) in the posterior spiracles.
What are the official names of this protein?
Transcription factor Ken, Protein Ken and Barbie.
What are the subcellular locations of this protein?
Nucleus.
Protein: VIE1_BHV4D
Sequence: MASKDSDVRCVKCQSLKPTTPLTGQDRCARCVAINELKPWISTCNINPCYDGDLSESNETIEMMDINSCREDTPSDAESETRFMPFVAHSKQPKHTSKNPTKGEIQYFPVEKCKDIHRVENQSSIDEEGKQCWICRDGESLPEARYCNCYGDLQYCHEECLKTWISMSGEKKCKFCQTPYKVNRQLSLKRGLPGYWDRDDRFVFIAGFIGMGTILAGWIASFFYLLVVLCGKYFTYKDVMIVVGGLAIIQVVGLMFSLFMYFQIGNLLRQYINYMTETNIDPLRT
What is the function of this protein?
Controls the expression of later classes of genes and also of the IE genes (Potential).  E3 ubiquitin-protein ligase (Probable).  E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
What are the official names of this protein?
Probable E3 ubiquitin-protein ligase IE1, 32.7 kDa immediate early protein IE1, RING-type E3 ubiquitin transferase IE1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IPYR_WIGBR
Sequence: MNLNSVPAGEKLPNDIYAIIEIPTNSNPIKYEVDKKTGILFVNRFIPTSMFYPCNYGYINHTISLDGDPLDILVPTPYPVLHGSVIRCNPIGVLKMIDESGEDAKIIAMPHQKLLAGYNNNIKNIDDISNLMKSQISHFFEHYKDLEKKKWTKVISWEDVKSAEKEILSSFNRKKTLNI
What is the function of this protein?
Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DGTL1_CAUVC
Sequence: MSQAPYFVPRAPYAEDPSKSKGRRFKEDESRTRTPFARDRDRIIHTSAFRRLKEKTQVFVAHEGDNFRTRLTHTLEVAQVARSLATALGLDADLAETIALAHDLGHPPFGHAGEDELEIQMREYGGFDHNVQTFRVVTELEHRYPDFIGLNLTWETLEGVIKHNGPVTNKLGKPSWKAISKYDNEYELGLGTWASAEAQVAALADDIAYNNHDVDDGVTAGLFTLDDLMDVPLIGPILAAVKSERPDLDARLTHLEAVRRMIGAMVDDVMGETLHRAAASGVQSADDVRALDHALVAFSSDMAEDLARLRGFLYERMYRHWRVNRTRSQARRILGEMFALFLREPEVLPTVWFAKSQNRDEAGRARVVCDYIAGMTDRFAIEEHRKLFHLDVWN
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase-like protein.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 2 subfamily.
Protein: SDHE_YERPS
Sequence: MEIDNKARIHWACRRGMRELDISIMPFFEYEYDSLSDNEKQAFIRLLECDDPDLFNWLMNHGEPQDSELYQMVKLIQSRNKARGPVAM
What is the function of this protein?
An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins.  Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol.  Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well.
What are the official names of this protein?
FAD assembly factor SdhE.
What is the protein family that this protein belongs to?
Belongs to the SdhE FAD assembly factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUDC_SALTI
Sequence: MDRIIEKLESGWWIVSHEQKLWLPYGELPHGLAANFDLVGQRALRIGEWQGEPVWLVLQHRRHDMGSVRQVIDQDAGLFQLAGRGVQLAEFYRSHKFCGYCGHPMHPSKTEWAMLCSHCRDRYYPQIAPCIIVAIRREDSILLARHVRHRNGVHTVLAGFVEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPKELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYD
What is the function of this protein?
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA.  The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing.  Has preference for mRNAs with a 5'-end purine.  Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.
What are the official names of this protein?
NAD-capped RNA hydrolase NudC, DeNADding enzyme NudC, NADH pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. NudC subfamily.
Protein: CYB_ALCBU
Sequence: MTNIRKTHPLMKIINNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYAFLETWNVGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALALSILILVLVPLLHTSKQRSMMFRPISQCMFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVLMPMASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: MPRF_STAES
Sequence: MTQELKSKLLSFFKFIFATALFIFVIFTLYRELSHINFKETFIQFGKINRLWLVLLFAGGGLSLILLSLYDIILVKALKLKMPLIRVFRVSYIINALNSIIGFGGFIGAGVRAFVYKNYTNDTKKLVQYISIILVSMLTGLSLLSILVVLRIFNASHMIDEISWVRWILYIVALFLPIFIFYTVARPVDRNNRYMGVYCTVVSCVEWMAAATVLYFAALIVDIHISFMTFVGIFVIAALSGLVSFIPGGFGAFDLVVLLGLKSLGISEEKILLALVLYRFAYYFVPVMIALILSSFEFGNTAKKYLDNSKYFIPVKDFTSFLRSYQKDILAKVPSFSLAILIFLTSIIFFINNLTIVYDGLYDGNHFAYYIALAVQTSACLLLILNVRGIYKGSRRAIIYAFISIILIASATIYTYASFLLLSWLIIIFVLLILAYQRAQVLKRPLRFKKLAVMLLLSIFILYLNHILISGTLYALDVYHIEIDTSLLRYYFWMTIVIIMLLVGVIAWLFDYKYKCPHHSIDLTLCDAIIQKYGGNYLSHLVYSGDKDCFFNENKDSFIMYRYKSNALVVLGDPIGNTKSFESLLEAFYQFAEYQGYEIIFYQISDQYMPLYHNFGNQFFKLGEEAIIDLTTFTTSGKKRRGFRATLNKFDDLNINFEIIEPPFTQDFFDELKFVSDKWLDGRSEMHFSVGQFTQTYLSKAPIGVMRDHSGKMIAFCSLMPTYSNNAISVDLIRWLPELDLPLMDGLYLHMLLWSKEKGYKAFNMGMATLSNVGQLHYSYLRERMAGRVFEHFNGLYRFQGLRRYKEKYSPNWEPRFLVYQKHYSLWESMLKVMRVIRHK
What is the function of this protein?
Catalyzes the transfer of a lysyl group from L-lysyl-tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge.  LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms (bacteriocins).  In fact, the modification of anionic phosphatidylglycerol with positively charged L-lysine results in repulsion of the peptides (By similarity).
What are the official names of this protein?
Phosphatidylglycerol lysyltransferase, Lysylphosphatidylglycerol synthase, LPG synthase, Multiple peptide resistance factor.
What is the protein family that this protein belongs to?
Belongs to the LPG synthase family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RS21_DESAP
Sequence: MAEVRVGKNETLDSALRRFKRTCQRAGVFAEARKHEHYEKPSVKRKKKSEAARRRKRSF
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: KTHY_CHLTA
Sequence: MFIVVEGGEGAGKTQFIQALSKRLIEEGREIVTTREPGGCSLGDSVRGLLLDPEQKISPYAELLLFLAARAQHIQEKIIPALKSGKTVISDRFHDSTIVYQGIAGGLGESFVTNLCYHVVGDKPFLPDITFLLDIPAREGLLRKARQKHLDKFEQKPQIFHQSVREGFLALAEKAPDRYKVLDALLPTEASVDQALLQIRALI
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.