PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_GEODF
Sequence: MDRTAAQLRIQELHREINRHNYLYYVEDRPEITDAEYDLLLRELQQLEKEFPDLVTADSPTQRVGAAPLDKFNQVSHRLPMLSLENAFNEGEMRDFDERIKRYLGLPMAKEIEYVCEPKMDGLAVELIYEEGSLTFGSTRGDGYVGEDVTQNLKTVKSIPLRLHCSPPPSLVEVRGEVYLGLAPFQKLNMDREEAGLPPFANPRNAAAGSLRQLDPRITARRPLSIFCYAPGLVEGYEFTSQSQMLATLPQWGLPVNPLIKKVAGIDAVLAYYREIGETRESLPYEIDGVVIKVDSFDLQRDLGEKTRSPRWAIAWKFPPRQAVTVVEDIVPQVGRTGVITPVAHLKPVEVSGVMVSRATLHNWEEMEKKDIRKGDTVVVERAGDVIPAVVKVMTEKRLEGAELLAVPAACPECGSEIVKIPGEVAIRCLGLTCPAQIRETIIHFASRHAMDIEGMGDKYVEQLLRLELVKTVADLYYLTKKDFMRFERMGDKLAENLLNAIEASKHRELSRFIFALGIRHVGEHTAKLLASAFGSVEHLEKATEEELLSIREVGPQVAQSVRTFFRNPANREVIERMFAAGVRPAVEEKRLGGRFTGKTFVFTGALTRFTRDDAKNMVENEGGHAAGSVSKKTDYVVAGAEAGSKLDKARQLGVNVLTEDEFLKMLEG
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: HEM1_YERPG
Sequence: MTLLALGINHKTAPVSLRERVTFSPESMDQALNSLLQQPLVQGGVVLSTCNRTELYLSVEQQENLHEQLTAWLCNYHKLSPDDVRQSLYWHHGNDAVRHLMRVASGLDSQVLGEPQILGQVKKAFAESQRGQSLSSELERLFQKSFSVAKRVRTETEIGASAVSVAFAACSLARQIFESLSELHVLLVGAGETIELVARHLREHQVKHMIIANRTRERAQSLASEVGAEVITLPEIDARLADADIIISSTASPLPIIGKGMVERALKTRRNQPMLFIDIAVPRDIEPEVGKLSNAYLYSVDDLQAIIQHNMAQRQAAAVQAESIVQQESMNFMTWLRAQGAVETIRDYRSQAEQVRSEMTAKALVAIEQGANVEQVINELAYKLTNRLIHAPTKSLQQAASDGDMERLQLLRDSLGLDQH
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: TRH_SHEEP
Sequence: QHP
What is the function of this protein?
Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
What are the official names of this protein?
Thyrotropin-releasing hormone, TRH, Protirelin, TSH-releasing factor, Thyroliberin, Thyrotropin-releasing factor, TRF.
What is the protein family that this protein belongs to?
Belongs to the TRH family.
What are the subcellular locations of this protein?
Secreted.
Protein: RPSB_CORDI
Sequence: MTSPSDVEASTETVDRGSRRNQTNDNPSADLVRVYLNGIGKTALLNAEDEVELAQTIEVGLYAEYLLENSQEPLTRAMKRDLKVLVKEGRKARSHLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYSKGFKFSTYATWWIRQAITRGMADQSRTIRLPVHLVEQVNKLSRIKREMYQQLGREATNEELAEESGIEESKIEMLLRQSRDPVSLDMPVGADEEAPLGDFIEDSEATDAESAVVASLRHSDIRTVLDTLEQREQDVIRLRYGLDDGVPRTLDQIGRQFGLSRERVRQIEREVMSKLRDGARAEKLRAYAQ
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
What are the official names of this protein?
RNA polymerase sigma factor SigB.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family.
Protein: Y1025_PSEF5
Sequence: MLMVISPAKTLDYETPPVTQRFTQPQYLDHSQELIQQLRELTPAQISELMHVSDKIGGLNAARFGSWTPAFTPDNAKQALLAFKGDVYTGLNAETLSEADFDYAQQHLRMLSGLYGLLRPLDLMQPYRLEMGTKLANARGKDLYAFWGTRISEWLNEALAEQGDDLLLNLASNEYFSAVKRTALNARIINTEFKDLKNGQYKIISFYAKKARGLMSRFVIQERINDPAQLKQFDVQGYRFSAEQSKADNLVFLRDHAPE
What are the official names of this protein?
UPF0246 protein PFL_1025.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: SYI_CHLTR
Sequence: MDNEDKISISAKEEKILSFWKEQDIFQKTLDNREGCPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYASMDGHYVPRRFGWDCHGVPVEYEVEKSLGLTEPGAIERFGVANFNEECRKIVFRYADEWKYFVDRIGRWVDFSATWRTMDLSFMESVWWVFRSLYDQGLVYEGTKVVPFSTKLGTPLSNFEAGQNYKEVDDPSVVVKFALQDNQGFLLAWTTTPWTLVSNMALAVHPELTYVRIKDKESGDEYILGQESLPRWFPDRESYEWIGQLSGKSLVGQSYEPLFPYFQDKKELEAFRILPADFIEESEGTGIVHMAPAFGEADFFACQEHNVPLVCPVDNQGCYTAEVKDFVGEYIKSADKGIARRLKNENKLFYQGTVRHRYPFCWRTDSPLIYKAVNSWFVAVEKVKSKMLKANESIHWTPEHIKQGRFGKWLEGARDWAISRNRYWGTPIPIWRSDDGELLVIGSIQELEALSGQKIVDLHRHFIDEIEINQNGKSFRRIPYVFDCWFDSGAMPYAQNHYPFERAEETEACFPADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKNVIVNGIILAEDGNKMSKRLNNYPSPKMIMDAYGADALRLYLLNSVVVKAEDLRFSDKGVESVLKQVLLPLSNALAFYKTYAELYGFDPKETDNIELAEIDRWILSSLYSLVGKTRESMSQYDLHAAVNPFVDFIEDLTNWYIRRSRRRFWDAEDSADRRAAFSTLYEVLVVFSKVIAPFIPFIAEDMYQQLRGETDPESVHLCDFPHVVLEKILPDLERKMQDIREIVALGHSLRKEHKLKVRQPLQNVYIVGSKERKEALAQVGSLIGEELNVKDVHFCSETPEYVTTLIKPNFRTLGKKVGNRLPEIQRALAGLPQEQIQAFMHKGQMVVSLGEETISLDKEDITVSWASAEGFVARSSASFVAVLDCQLTEPLIMEGIARELVNKINTMRRNRKLHVSDRIAIRLHAPVIVQEAFALHKEYICEETLTTSVSVIDYKEGEEWDINGHAVSFVLERVER
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MB12A_XENLA
Sequence: MENSSTPITGLAWISSVTLCPKTYNMIVATVEGASANFVKGFNQKSAVYLGYSTVPEGLEQVITDIQMLNEKTVLPVGYAFIGEHLDPKISVPKKKRLCVKQMPMHTAETAVCEIKLSMKSKQFGAPYERIGEISGLVFWCRKGSVSAPKPTPKPRNITSGIKGLSLDSNTAVQPVRRASAPNPDAGQAVPLSNGKWGLSENAIYDSSNIYGISAIDGIPFTIHPMFENTINNSSVAASDFRDLHIKTLSEIESEYNYGFVVEKTAAARIPPRLR
What is the function of this protein?
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.  Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (By similarity).
What are the official names of this protein?
Multivesicular body subunit 12A, ESCRT-I complex subunit MVB12A, Protein FAM125A.
What is the protein family that this protein belongs to?
Belongs to the MVB12 family.
What are the subcellular locations of this protein?
Cytoplasm. Endosome. Late endosome membrane; Peripheral membrane protein. Note=Colocalizes with F-actin.
Protein: PPK1_NEIMA
Sequence: MPEQNRILCRELSLLAFNRRVLAQAEDKNVPLLERLRFLCIVSSNLDEFFEVRMAWLKRENKLHPRRRLDNGKMPSETIADVTEAARSLIRHQYDLFNNVLQPELARESIHFYRRRNWTGAQKKWIEDYFDRELLPILTPIGLDPSHPFPRPLNKSLNFAVELDGTDAFGRPSGMAIVQAPRILPRVVPLPSELCGGGHGFVFLSSILHAHVGKLFPGMNVKGCHQFRLTRDSDLTVDEEDLQNLRAAIQNELHDREYGDGVRLEVADTCPAYIRDFLLAQFKLTAAELYQVKGPVNLVRLNAVPDLVNRPDLKFPTHTPGRLKALGKTASIFDLVRQSPILLHHPYQSFDPVVEMMREAAADPDVLAVKMTIYRTGTRSELVRALMKAALAGKQVTVVVELMARFDEANNVNWAKQLEEAGAHVVYGVFGYKVHAKMALVIRREDGVLKRYAHLGTGNYHQGTSRIYTDFGIITADEQITADVNTLFMEITGLGKPGRLNKLYQSPFTLHKMVIDRIARETEHAKAGKPARITAKMNSLIEPTVIEALYRASAAGVQIDLIVRGMCTLRPGVKGLSENIRVRSIIGRQLEHARVYCFHNNGADDTFISSADWMGRNFFRRIETAAPITAPELKKRVIREGLEMALADNTHAWLMQPDGGYIRAAPAEGESEADLQNDLWTLLGG
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).
What are the official names of this protein?
Polyphosphate kinase, ATP-polyphosphate phosphotransferase, Polyphosphoric acid kinase.
What is the protein family that this protein belongs to?
Belongs to the polyphosphate kinase 1 (PPK1) family.
Protein: TIDC1_MOUSE
Sequence: MGAPPPAPRSRLCGAWGPFPRVFAAGAVAADSPGFVEDREQRSGVSDPGSLESGWDRLRQLFAKDEQQRFSKEIDYIYRAAVSAGIIGWAYGGIPAFIYAKKRYIEQSQAEIYHNRFDAVQSAHRAATRGFIRYGWRWSWRTAVFVTIFNTVNTGLTVYRNKDAMSHFAIAGAVTGGLFRINLGVRGLVAGSIIGALLGAPMGSLLMALEKYSGETVQERRQKEWKALHEQRLEEWRSSLQVTELLPMEIESGLEKIQPEGDAQRIEELLSLPRNPSSPHQQSKH
What is the function of this protein?
Chaperone protein involved in the assembly of the mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).  Participates in constructing the membrane arm of complex I (By similarity).
What are the official names of this protein?
Complex I assembly factor TIMMDC1, mitochondrial, Translocase of inner mitochondrial membrane domain-containing protein 1, TIMM domain containing-protein 1.
What is the protein family that this protein belongs to?
Belongs to the Tim17/Tim22/Tim23 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: MNMA_CUTAK
Sequence: MKVLAAMSGGVDSAVAAARLVEAGHDVTGVHLALSRNPRSHREGSRGCCSLEDSFDARRAADRLGIPFYVWDFSDRFVAEVIDPFIAEYRAGRTPNPCLRCNERIKFAALLERGLDLGYDAVATGHYARTKVVDGVTKLYRSVDPGKDQSYVLAVLNQDQLSHSLFPLGNSLKMNVRQEAAALGLSVADKPDSNDICFIPDGDTPGWLSEKIGSADGEIRDESGALVGHHNGYHHFTIGQRRGLRLGVPAPDGKPRYVLDIEPVNNTVVVGGAEGLTVHHIEAIRPVWCSSEPVETWHGQAQVRAHGDPVPAIISAVPGGVAVELEDSLRGVAPGQAAVFYDGDLVVGSATICGTDRAGVKAEQAA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL44_CANTR
Sequence: MVNIPKTRNTYCKGKGCRKHTIHKVTQYKAGRASLFAQGKRRYDRKQSGYGGQTKQVFHKKAKTTKKIVLKLECTVCKTKKQLPLKRCKHIELGGEKKQKGQALQF
What are the official names of this protein?
60S ribosomal protein L44, 60S ribosomal protein L41.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
Protein: COX3_RHIST
Sequence: MIEMYDRNYIYNMTTKIMNRSVQAHPFHLVEASPWPIAVSFSLLVVTLSGVMTFQGYSNGLFLLTLGFISLVSTMTLWFKDISREGTFQGHHTFAVQKGLSLGFVLFVVSEVFFFISIFWAFFHSALAPTVELGAHWPPAGIETLNPWEVPLLNTVILLSSGATVTYAHHANPSNRAGVIYGLIATIVLATVFTGFQGFEYYNAPFTFSDGVYGSTFYMATGFHGIHVLVGTIFLTVGLFRVLSYHLTDHHHLGFEQAILYWHFVDVVWLFLFISVYWWGG
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 3, Cytochrome c oxidase polypeptide III.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 3 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: YAAI_SHISS
Sequence: MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNDLALKLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
What are the official names of this protein?
UPF0412 protein YaaI.
What is the protein family that this protein belongs to?
Belongs to the UPF0412 family.
Protein: PHAF_RHIME
Sequence: MELAVVWSVLVAQTMLALAMAFALYRMARGPRAQDRILGLDTLYINAMLMLITFGIRTANTVYFETALIIAVIGFASSIALAKFLMRGEVIE
What is the function of this protein?
Part of a K(+) efflux system which is required for the adaptation of R. meliloti to alkaline pH as well as for the infection process during symbiotic nodule development.
What are the official names of this protein?
Probable K(+)/H(+) antiporter subunit F, pH adaptation potassium efflux system protein F, Pha system subunit F.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CYC_ARATH
Sequence: MQVADISLQGDAKKGANLFKTRCAQCHTLKAGEGNKIGPELHGLFGRKTGSVAGYSYTDANKQKGIEWKDDTLFEYLENPKKYIPGTKMAFGGLKKPKDRNDLITFLEEETK
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: RPN12_YEAST
Sequence: MPSLAELTKSLSIAFENGDYAACEKLLPPIKIELIKNNLLIPDLSIQNDIYLNDLMITKRILEVGALASIQTFNFDSFENYFNQLKPYYFSNNHKLSESDKKSKLISLYLLNLLSQNNTTKFHSELQYLDKHIKNLEDDSLLSYPIKLDRWLMEGSYQKAWDLLQSGSQNISEFDSFTDILKSAIRDEIAKNTELSYDFLPLSNIKALLFFNNEKETEKFALERNWPIVNSKVYFNNQSKEKADYEDEMMHEEDQKTNIIEKAMDYAISIENIV
What is the function of this protein?
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.  Necessary for activation of the CDC28 kinase.
What are the official names of this protein?
26S proteasome regulatory subunit RPN12, Nuclear integrity protein 1.
What is the protein family that this protein belongs to?
Belongs to the proteasome subunit S14 family.
Protein: GLPK_HALH5
Sequence: MTKKYILALDQGTTSSRAILFNEAGEIIGIEQKEFQQIFPKPGWVEHDANEIWASVLSVIAGVLLKTNVEAKEIAAIGITNQRETAVVWEKESGRPIYNALVWQSRQTAGICERLRAEGFSEMVTEKTGLLIDPYFSGTKVRWILDHVDGAQERAERGELLFGTIDTWLIWKLSGGKAHVTDYSNASRTLLYNIYEQCWDDELLKMLNVPRAMLPDVRPSSEVYAETVSYHFFGEEIPIAGAAGDQQAALFGQACFEKGMAKNTYGTGCFMLMNTGNQGVKSKHGLLTTIAWGLDGKVEYALEGSIFVAGSAIQWLRDGLRMMKSAKESEGYATKVTSADGVYVVPAFVGLGTPYWDSDVRGAVFGLTRGTSKEHFIRATLESLAYQTKDVLQAMEADSGISLKTLRVDGGAVANNFLMQFQSDLLGVSVERPTVQETTALGAAYLAGLAVGFWTSKEEITNNWNLEQKFSAEMEETDRAKLYEGWQKAVRAAQAFK
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: SEPF_LATSS
Sequence: MAGKFSFSNFFGMTEDEDYSTDLQGTKTTDEVSPTSRPDNIISMTAAGNAKMNKIVLCEPRIYSDAKKVGKHLLENKAVIVNFTRIEGAQASRIIDFLTGTVFAINGEIQRVGEQIFLCTPPNYEIDGNLSDIIDQNDFDSEVN
What is the function of this protein?
Cell division protein that is part of the divisome complex and is recruited early to the Z-ring.  Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments.  Its function overlaps with FtsA.
What are the official names of this protein?
Cell division protein SepF.
What is the protein family that this protein belongs to?
Belongs to the SepF family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the division site, in a FtsZ-dependent manner.
Protein: MURA2_STAAM
Sequence: MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKALGADIWTETV
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2, Enoylpyruvate transferase 2, UDP-N-acetylglucosamine enolpyruvyl transferase 2, EPT 2.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YAII_ESCF3
Sequence: MTIWVDADACPNVIKEILYRAAERMQLPLILVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEPGDLVITADIPLASEVLAKGAAALNPRGERYSEATIRERLTMRDFMDTLRASGIQTGGPDALSPRDRQHFAAELDKWWLEAKRKKESM
What are the official names of this protein?
UPF0178 protein YaiI.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: ENO_SYNWW
Sequence: MSTIVDVFAREVLDSRGNPTVEVEVFLEDGTMGRAIVPSGASTGAHEAVELRDGDSKRYLGKGVLQAVDNVNMIIAPEVIGMDATAQIDIDQLMIDLDNTPNKAKLGANAIMGVSLATARAAATHLAIPLYQYIGGVNAREIPVPMMNILNGGKHADNNVDIQEFMIVPSGAPNFAEGLRMGVEVYHSLKKVLNNKGLGSGVGDEGGFAPNLPSNEAALDLILEAIAAAGYQAGSDINLALDVAATELFKDGKYHLASSGQVLSSSEMVDFYAQMLEKYPLISLEDGLAEDDWDGWKQLTERLGSKIQLVGDDLFVTNSQRLARGIEEGVCNSILIKVNQIGTLSETLNTIEMARRAGYTCVISHRSGETEDSTIADIAVATNAGQIKTGAPARSDRVAKYNQLLRIEEELDVFAVYRGIKAFKR
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PSRP_ECO8A
Sequence: MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSRCGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Phosphoenolpyruvate synthase regulatory protein, PEP synthase regulatory protein, PSRP, Pyruvate, water dikinase regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PSRP subfamily.
Protein: ATPMK_BOVIN
Sequence: MAGPEADAQFHFTGIKKYFNSYTLTGRMNCVLATYGSIALIVLYFKLRSKKTPAVKAT
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain.  F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk.  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.  ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria.
What are the official names of this protein?
ATP synthase membrane subunit K, mitochondrial, ATP synthase membrane subunit DAPIT, mitochondrial, Diabetes-associated protein in insulin-sensitive tissues, Up-regulated during skeletal muscle growth protein 5.
Protein: MINC_THENN
Sequence: MIDFKMTKEGLILLIRDYQNLEEVLNEITSRVTQMGGFFAKGDRISLMIENHTKHSQDIPKIVSRLRELGLEVSQILVGSTIEGKENDVRVESRTTVESTGKVIKRNIRSGQTVVHSGDVIVFGNVNKGAEILAGGSVVVFGKAQGNIRAGLNEGEQAVVAALDLQTSLIQIAGFITHSKGEENVPSIAHVKGNRIVIEPFDRVDFERSE
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: DMS4_PHAJA
Sequence: ALWKDMLSGIGKLAGQAALGAVKTLV
What is the function of this protein?
Has antimicrobial activity.
What are the official names of this protein?
Dermaseptin-J4, DRS-J4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DNSL1_HUMAN
Sequence: MHYPTALLFLILANGAQAFRICAFNAQRLTLAKVAREQVMDTLVRILARCDIMVLQEVVDSSGSAIPLLLRELNRFDGSGPYSTLSSPQLGRSTYMETYVYFYRSHKTQVLSSYVYNDEDDVFAREPFVAQFSLPSNVLPSLVLVPLHTTPKAVEKELNALYDVFLEVSQHWQSKDVILLGDFNADCASLTKKRLDKLELRTEPGFHWVIADGEDTTVRASTHCTYDRVVLHGERCRSLLHTAAAFDFPTSFQLTEEEALNISDHYPVEVELKLSQAHSVQPLSLTVLLLLSLLSPQLCPAA
What are the official names of this protein?
Deoxyribonuclease-1-like 1, DNase X, Deoxyribonuclease I-like 1, DNase I-like 1, Muscle-specific DNase I-like, XIB.
What is the protein family that this protein belongs to?
Belongs to the DNase I family.
What are the subcellular locations of this protein?
Endoplasmic reticulum.
Protein: TIO_ATHV3
Sequence: MANEPQEHEEGKPFFPPLGDSGEEGPPNIPQDPTPGTPPGPINSKNEDYPPPLENPGPNKSEGPPDGSGNSSPPVTMLVKNNGDRTKQDVSESGGNNSAPNSVESKHTSSSSSAGNGNETKCPDEQNTQECITTIYIPWEDAKPKLMGLVKLDSSDSEEERSPFNKYPKNYKKLRVDMGENWPPGIPPPQLPPRPANLGQKQSATSKNGPQIILREATEVESQQATDGQLNHRVEKVEKKLTCVICLLIGILVLLILLFMLGFLFLLMK
What is the function of this protein?
Transforms host T-cells, inducing T-cell lymphomia in the host.  Activates at least SRC and LCK tyrosines kinases, thereby activating signaling pathway transforming host T-cells.  Human T-cells transformed ex vivo display a IL2 indenpendent growth phenotype.
What are the official names of this protein?
Protein tio.
What are the subcellular locations of this protein?
Host cell membrane; Single-pass membrane protein. Note=Associated with plasma membrane, presumably via its putative transmembrane domain.
Protein: KUP_ACIBC
Sequence: MQNTAKKATLPATALAALGVVFGDIGTSPLYALKESFHAAHGLGIQPENVLGILSIIFWCLMLIISIKYVAIVMRADNNGEGGIMALLALNLRKAKIADNKKIYMIAIGFIGASLFFGDGIITPAISVLSAVEGLSIATDVFDPFIMPIAIAIIVTLFLVQKHGTAFVGKFFGPITLVWFLSLGILGIHSVIQTPVVLGMFSPHWAIQFIYHHPIMTFFVMGAVVLTVTGGEALYADMGHFGPVPIRLAWFFVVLPCLVLNYAGQGALLLRDPAAIENPFYLLVPQWALYPMIIMATMATVIASQAVISGVFSLARQAIQLGYLPRLSIKHTSESEEGQIYVPFLNWLLLIAIIILILIFKTSSNLASAYGLAVTLTMLCDTILVAVFIYSAWKWSLPKVLLLIIPFFILESVLVGATSLKILSGGWVPLLIGAIAVTILMTWKRGRELTFAKLEHDTLSLDLFVKSIGNSVHWVPGDAVFMTGTPNVVPHAMLHNIKHNKVLHQRNILVTVVIEDVPFVAPEERITTETLAEHFFRIKIFYGFKDEMNVPKALMQAYEQLGLEYDLMHISFFISRDRIVHSVGDGMSPWREKLFISMQRNTSPVSDFYQIPTNRVVELGSQIEI
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SP2AB_BACAH
Sequence: MRNEMNLQFSALSQNESFARVTVAAFIAQLDPTMEELTEIKTVVSEAVTNAIIHGYEGNAEGVVYISVILEEAMVKLTIRDEGIGIFNLDEARQPLFTTKPELERSGMGFTIMENFMDEVEVISNESFGTTIHLTKYLSNSNALCN
What is the function of this protein?
Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F).  Phosphorylates SpoIIAA on a serine residue.  This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
What are the official names of this protein?
Anti-sigma F factor, Stage II sporulation protein AB.
What is the protein family that this protein belongs to?
Belongs to the anti-sigma-factor family.