PharMolix/UniProtQA huggingface dataset:
Protein: DNAK_BACCN
Sequence: MSKIIGIDLGTTNSCVAVMEGGEPKVIPNPEGNRTTPSVVAFKNDERQVGEVAKRQAITNPNTIMSIKRHMGTDYKVEIEGKKYTPQEISAIILQNLKASAEAYLGEPVTKAVITVPAYFNDAERQATKDAGRIAGLEVERIINEPTAAALAYGLEKQDEEQKILVYDLGGGTFDVSILELADGTFEVISTAGDNRLGGDDFDQVIIDYLVAEFKKENNIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFISAGAAGPLHLELNLTRAKFEELSANLVERTLEPTRRALKDAGLSASDLDKVILVGGSTRIPAVQEAIKRETGKEPYKGVNPDEVVALGAAVQGGVLTGDVEGVLLLDVTPLSLGIETMGGVFTKLIERNTTIPTSKSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPPAPRGIPQIEVTFDIDANGIVNVRAKDLGTNKEQAITIQSSSGLSDEEVERMVKEAEANADADQKRKEEVELRNEADQLVFQTDKVVKDLEGKVDAAEVAKATEAKDALKAAIEKNDLDEIRAKKDALQEIVQQLTVKLYEQAQAAAGAQQAEGAQGNAGAKNDNVVDAEFEEVKEDK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: PLST_RAT
Sequence: MDEMATTQISKDELDELKEAFAKVDLNSNGFICDYELHELFKEANMPLPGYKVREIIQKLMLDGDRNKDGKISFNEFVYIFQEVKSSDIAKTFRKAINRKEGICALGGTSELSSEGTQHSYSEEEKYAFVNWINKALENDPDCRHVIPMNPNTDDLFKAVGDGIVLCKMINLSVPDTIDERAINKKKLTPFIIQENLNLALNSASAIGCHVVNIGAEDLRAGKPHLVLGLLWQIIKIGLFADIELSRNEALAALLRDGETLEELMKLSPEELLLRWANFHLENSGWQKINNFSADIKDSKAYFHLLNQIAPKGQKEGEPRIDINMSGFNETDDLKRAESMLQQADKLGCRQFVTPADVVSGNPKLNLAFVANLFNKYPALTKPENQDIDWTLLEGETREERTFRNWMNSLGVNPHVNHLYVDLQDALVILQLYERIKVPVDWSKVNKPPYPKLGANMKKLENCNYAVELGKNQAKFSLVGIGGQDLNDGNPTLTLAVVWQLMRRYTLNVMEDLGEGQKATDDIIVNWVNGTLSEAGKSTSIQSFKDKTISSSLAVVDLIDAIQPGCINYDLVKTGNLTEEDKHNNAKYAVSMARRIGARVYALPEDLVEVKPKMVMTVFACLMGRGMKSV
What is the function of this protein?
Actin-bundling protein.
What are the official names of this protein?
Plastin-3, T-plastin.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1737_BRUAB
Sequence: MSDDITSEAQTIAVGQLRAFIERIERLEEEKKTIGDDIKEVYAELKGSGFDSKVVRTIIRLRKKEDHERQEEEAMLQLYMDALGMS
What are the official names of this protein?
UPF0335 protein BruAb1_1737.
What is the protein family that this protein belongs to?
Belongs to the UPF0335 family.
Protein: ATP6_CHLT3
Sequence: MIYLHNKRKGMLKRLSALIVIGLLMNLPAVFASGGEHAEAAHGDAAHAEAAHGGGAHHDPEKLDAIHHVIDGHEFDFEPFGIVHLPKIEVGGFDISLTRHVVMMWIAAAILLLIMFGVGNQYKKMTKNQAPKGMANLMEVLVDFIRLDVAKQNIGHGYERFMPFLLTIFFFILVCNLIGLVPYSATATGNINVTATLAIFTFLVTQASAIRAHGIGGFLAHLTGGTHPLMWIIMVPVEFIGLFTKPFALTVRLFANMTAGHIVIISLLGLIFVFKTYMIAPVSVAFALFIYLLEILVAFLQAYIFTLLSALFIGMAVAHEDHGDEAHGHAPSH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: M1015_BOMMX
Sequence: MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGALLSAGKSALKGLAKGLAEHFASGKRTAEDHEVMKRLEAVMRDLDSLDYPEEATERETRGFNQEEIANLFTKKEKRILGPVLGLVGNALGGLLKNLG
What is the function of this protein?
Maximin-H15 shows antimicrobial activity against bacteria and against the fungus C. albicans.  Shows strong hemolytic activity (By similarity).
What are the official names of this protein?
Maximins 10/H15.
What is the protein family that this protein belongs to?
Belongs to the bombinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DXR_CLOBH
Sequence: MKNITILGATGSIGTQTLDVIRREKEELKLVAISANKSDKKVIEIIKEFKPKYAVLMEENAFKIVEDFCIDNKIDTKVLKGMEGMIYISTLEEVNTVVTSVVGMIGLVPTIKAIESGKDIALANKETLVVAGELVISKAKEHNVNILPVDSEHGAIFQCLRGNKKEEVKNIIVTASGGPFRGKKKEELIDVKPEHALKHPKWNMGRKISIDSATLMNKGLEVIEAHFLFGVDYENIKVVVHPQSIVHSMVEYKDGSVIAQMATPDMKLPIQYALNYPNRKESQIEPLDFYKISNLTFEKPDMDTFLPLKLAYEAGKKGGVMPAILNGANEVAVDLFLKGKIEFLQIGDLLQECMNKFYKSMEATLENVISVDKEVREYLGKKYDI
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: ENV_MCFF
Sequence: MEGPAFSKPLKDKINPWGPLIILGILIRAGVSVQHDSPHQVFNVTWRVTNLMTGQTANATSLLGTMTDAFPKLYFDLCDLIGDDWDETGLGCRTPGGRKRARTFDFYVCPGHTVPTGCGGPREGYCGKWGCETTGQAYWKPSSSWDLISLKRGNTPRNQGPCYDSSVVSSGIQGATPGGRCNPLVLEFTDAGKKASWDGPKVWGLRLYRSTGIDPVTRFSLTRQVLNIGPRLPIGPNPVITGQLPPSRPVQIRLPRPPQPPPPGAASIVPETAPPSQQPGTGDRLLNLVDGAYQALNLTSPDKTQECWLCLVAGPPYYEGVAVLGTYSNHTSAPANCSVASQHKLTLSEVTGQGLCVGAVPKTHQALCNTTQKTSDGSYYLAAPAGTIWACNTGLTPCLSTTVLNLTTDYCVLVELWPKVTYHSPDYVYTQFEPGARFRREPVSLTLALLLGGLTMGGIAAGVGTGTTALVATQQFQQLQAAVHNDLKEVEKSITNLEKSLTSLSEVALQNRRGLDLLFLKEGGLCAALKEECCFYADHTGLVRDSMAKLRERLNQRQKLFESGQGWFEGLFNRSPWFTTLISTIMGPLIVLLLILLFGPCILNRLVQFVKDRISVVQALVLTQQYHQLKPIEYEP
What is the function of this protein?
The transmembrane protein (TM) acts as a class I viral fusion protein.  Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state.  During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.  The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.  Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm (By similarity).
What are the official names of this protein?
Envelope glycoprotein, Env polyprotein.
What are the subcellular locations of this protein?
[Transmembrane protein]: Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. SUBCELLULAR LOCATION: [Surface protein]: Virion membrane; Peripheral membrane protein. Host cell membrane; Peripheral membrane protein. Note=The surface protein is not anchored to the viral envelope, but associates with the virion surface through its binding to TM. Both proteins are thought to be concentrated at the site of budding and incorporated into the virions possibly by contacts between the cytoplasmic tail of Env and the N-terminus of Gag (By similarity). SUBCELLULAR LOCATION: [R-peptide]: Host cell membrane; Peripheral membrane protein. Note=The R-peptide is membrane-associated through its palmitate.
Protein: FADB_SERP5
Sequence: MLYQGETLQLHWLDNGIAELVFNAPGSVNKLDTRTVASLGEALAVLEKQTELKGLLLRSTKAAFIVGADITEFLSLFAAPAEKLQEWLNFANAIFNRLEDLPVPTISAINGYALGGGCECILATDFRVASPDARIGLPETKLGIMPGFGGSVRLPRLLGNDSALEIIAAGKDVSAKDALKVGLVDAVVAPEKLVEAALKMLQQAIEGKLDWRAYRQPKLEPLKLSPIEAAMSFTTAKGMVMQTAGKHYPAPMTAVKTIEAAARLGRDEALKLETASFVPLARSKEARALVGIFLNDQFVKGQAKKLAKGIEAPKQAAVLGAGIMGGGIAYQSALKGVPVVMKDISDKSLTLGMNEAAKLLNKQLERGKLDGMKMAQVLSTIQPTLDYAGIERAQVIVEAVVENPKIKAAVLSEVEGLIGENTVLASNTSTIPINHLAKSLKRPQNFCGMHFFNPVHRMPLVEIIRGEQTSDSTIAAVVAYASRMGKTPIVVNDCPGFFVNRVLFPYFAGFSMLLRDGADFRQIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPERMGKDYRDAIDVMFDNQRFGQKNQLGFYRYSQDNKGKPRKDNDEQTDVLLAEVSQPRQTISDEEIIARMMIPMINEVVRCLEENIIASPAEADMALVYGIGFPPFHGGAFRYLDTLGTANYVELAQRYAHLGALYQVPAGLRAKAEHNESYYPVAAPLSDVSTGQPA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: RL29_BURVG
Sequence: MKASELLQKDQAALNKELADLLKAQFGLRMQLATQQLTNTSQLKKVRRDIARVRTVMTQKANQK
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RSMH_CHLTE
Sequence: MDYQDYHEPVLARESVSLLVTLPGIYIDGTLGGGGHSLQLLRHLQTLNGDSLLVGIDQDTHALEAAGKKLGEFGDRRRLVRGNFGMVKELVEPMMRGAGNGLPVMGFLLDLGVSSFQIDTPERGFSYLKDGPLDMRMDPDGPLTAADIVNGYEEAALAKLFFRYGEEPLGGRIARAIVSARSSAPLTTTGELAEVIRAACPRKDLAIKTLSRIYQALRIEVNDELGVLEQALEDGFELLSSGGRFAVISYHSLEDRIVKRFFAAKTSADWGPKGLALREPLKPAEAVLVVRKPLEATAEEISRNPRSRSARLRVIQKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NQOR_SHISS
Sequence: MSVKARILVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMPPQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
What are the official names of this protein?
NAD(P)H dehydrogenase (quinone), Flavoprotein WrbA, NAD(P)H:quinone oxidoreductase, NQO.
What is the protein family that this protein belongs to?
Belongs to the WrbA family.
Protein: RUTC_ECO26
Sequence: MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLEIIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
What is the function of this protein?
Involved in pyrimidine catabolism.  Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously.  RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions.
What are the official names of this protein?
3-aminoacrylate deaminase RutC, 3-AA deaminase.
What is the protein family that this protein belongs to?
Belongs to the RutC family.
Protein: 227L_IIV6
Sequence: MNQLNQFILIFLLLIVILFIFFLIPKKEPEIKTFAYEVPIRYSNPRSLYSLPKWKTFYGRNWL
What are the official names of this protein?
Uncharacterized protein 227L.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: FKBP4_CRYNJ
Sequence: MPLAMNLWSLTLLPGQQYPTYVRRDFQITNAALGEELRSKDGRSVVKVTHNPISQSMLESDDEWSDEDEDEEILSEEDDGEMEVEEVKQKKGKKAEKVEEEDSEEEDEDESDFEDELEETNVLCSLTAGKTEQASLNLTFVRGEVVVFEVTGDNVVHLMGNYIQQDEDSDDESDSDFDGEDDYSELYGSDDDLELDSEEEAAVAKITEIPDEPTPKTKKALPAADKKPVPEAKPAQKRKAEELESPAKEDAALSKAQKKKLAKKAKVEGEKAEEKPAAAAVAEKPATKKEAKAPQKKTLPSGLIIEDIKIGDGPVAKTGKRLGMRYIGKLTNGKQFDANTSGKPFSFVLGKGEVIRGWDEGLAGMAVGGERRLTIPAALAYGNQKIPGIPKNSTLKFDVKLVSIN
What is the function of this protein?
PPIase that acts as a histone chaperone.  Histone proline isomerase that increases the rate of cis-trans isomerization at prolines on the histone H3 N-terminal tail.  Proline isomerization influences H3 methylation thereby regulating gene expression.
What are the official names of this protein?
FK506-binding protein 4, Histone proline isomerase, Peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: TAL_STRPD
Sequence: MKFFLDTANVAAIKAINELGVVDGVTTNPTIISREGRDFETVIKEICDIVDGPISAEVTGLTADAMVEEARSIAKWHDNVVVKIPMTTEGLKATNILSKEGIKTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGTDAYQLISDLREIIDLYDFQTEIIAASIRTTAHVEAVAKLGAHIATIPDPLFAKMTQHPLTTNGLKTFMEDWASFKK
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Probable transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 3B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIR1_GIBZE
Sequence: MSALTKIREGLAREDNTHVAGTLAPHEKEIHETPEVVSEVGPDHDKEATAGAINPDDKGNDSDVPSEDVQNGVKEIQAITLTWGKGSLAALLCLIWTLFLISGFRGSFYLVLVPYVTSEWSAHSLMTTIPIVSDAMTAACYIPMAKALDVWGRAEGFLLMSGFATLGLILMAVSQNLATFCAAQVFYSVGWGGMIYAVGVLAADASNLRNRGLAFAFTSSPYMITAFAGSKAAAAFVIDVKNWRWGFGWIALVLPCVTIPLFLVLKVNLRKAFKNGTVTKTTRNRGFFGSIWWAFNEFDVIGIFLFGGGLVVFLLPFNLAGHAPNGWSTGYIIAMIIVGFCTLIFFGVWEYWLAPVPFLQGRFLLDRSVVAACMIDLTYQVSYYTWNYFFTSFLQVVVNLGPAEAGYVNSTFQVVSGVLLFIVGFLIRKTGFYKWTFYFAVPIYIFALGLMIHFRAPNQYVGYIIMCEIFISIGGAVFILVMQLAVLAAVAHQYVAAALATLYVAGGVGGAVGGAISGAIWTNSFIPQLIKRLPESEVANATLIAGSIVNQLAYPVDSPARLAIQESYGFAQIRMLAAGVGIASLFFIWVPMLRNIDVKKLKQTKGLVL
What is the function of this protein?
Major facilitator transporter involved in extracellular siderophore uptake (PubMed:20507510).  Gibberella zeae produces extracellular coprogen-type siderophores as well as the intracellular siderophore ferricrocin (PubMed:17056706).  The role of extracellular siderophores is to supply iron to the fungus during plant infection, and the intracellular ferricrocin is required for intracellular iron distribution and storage with a crucial role in ascus and ascospore development (PubMed:17056706, PubMed:17043871, PubMed:17601875).
What are the official names of this protein?
MFS siderochrome iron transporter 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYP_DEHM1
Sequence: MRYSRLFGKTQREIPSDAETISHQLLLRSGMIAQLTAGVYSFMPLAWRSIQKIENIIRQEMNKSGCQELAMPVLQPVEIWQQSGREAPFGQTLFHLKDRKDRNLVLGPTHEEVITDLASRYIQSYRDLPQRLYQIQTKFRDEPRPRGGLIRVREFIMKDMYSFDASPEGLDESYQTMKQAYENVYRRCGLESMVIDADSGAIGGKASHEFMIVAESGEDSIIYCPKCNYAANAEKAVFKKKTLPKEPPKDLEEVATPGQKTISEVAAFLSLKPENTLKAVFYMADGKFVMAVIRGDLDINEIKLKNLLKCNDLRLAEDSEVKAAGIAAGFASPVGLKNSLTVADDSVENGSNFVAGANKDGFHLKNVNFGRDFKADKMADIALAAEGAACPFCDGTFASKRGVEVGHIFKLGTFLSERFGANFTDAEGISHPIIMGCYGMGVGRLLAAAIEQNHDEKGIIWPMPIAPYQIYICGLFLDNPAVSQAAEKIYTELEAQGVEVLFDDRELTAGVKFNDADLLGIPLRLTISPRNLDKGGVELKLRRNKESELVPLESIMERVITCIKSQSDL
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LECA_CANBL
Sequence: ADTIVAVELDTYPNTDIGDPSYPHIGIDIKSVRSKKTAKWNMQNGKVGTAHIIYNSVGKRLSAVVSYPNGDSATVSYDVDLDNVLPEWVRVGLSATTGLYKETNTILSWSFTSKLKSNSTHETNALHFMFNQFSKDQKDLILQGDATTGRDGNLELTRVSSNGSPQGSSVGRALFYAPVHIWESSAVVASFDATFTFLIKSSDSHPADGIAFFISNIDSSIPSGSTGRLLGLFPDAN
What is the function of this protein?
D-mannose/D-glucose-binding lectin (PubMed:24865454).  Has anti-inflammatory activity in animal models when applied intravenously (PubMed:24865454).  Has antinociceptive activity in mice when applied intravenously (PubMed:19705102).
What are the official names of this protein?
Lectin alpha chain, CboL.
What is the protein family that this protein belongs to?
Belongs to the leguminous lectin family.
Protein: THII_STRP2
Sequence: MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYSQVKVTADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKEGMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAYLSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPGALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIREVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTFDISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAEKDEVDDLIDNLL
What is the function of this protein?
Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor.  Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate.  This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway.  The sulfur is donated as persulfide by IscS.
What are the official names of this protein?
Probable tRNA sulfurtransferase, Sulfur carrier protein ThiS sulfurtransferase, Thiamine biosynthesis protein ThiI, tRNA 4-thiouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HXK_BRUMA
Sequence: MLGLLTITSVFRNWRNSLQRKEDYDECHMRGINNENEISGKSEKNFKLDEPPISLETVMAEFKLSNETLRRMMAHMSRNMDKGLEGGPENSTISMLPSFVPELPNGTEEGRFIAMDLGGTNLRVMLMDIKPGEELKTEQFNTRIPNWAMRGTGEQLFDYITKCLAEFLIEKGIENDGLPVGFTFSYPCDQKSLRSATLLRWTKGFETTGVVGEDVVELLEQSIARRGDIKVEVVALINDTVGTMVAAAHESGGECHIGVIIATGTNASYMEDTSKIKYGLSKAIAAYNYPEMIIDTEWGGFGDRSEADYILTQYDKIVDSRSEHPGVNTFDKLVGGKCMGEVVRVVLEKLTRARVLFNGKGSDALFQQDSFPTKYISEILRDESGSYVHTRDILGELGIDHYSFSDMLLLREVCVVVSRRSANLGAAAIACVLNRVRKQNMVVGIDGSTYKYHPFFDFWVHDKLKELVDPGLKFKLLQTADGSGKGAALITAIVARLKKRNLKQQQQQQQQQQQHVTMVEQNVVEQIAETKGSREQFMNGNQKINLVTNDIPIYDSFNGDIENGVIHLSTDH
What is the function of this protein?
Active against glucose, fructose, mannose, maltose and galactose.
What are the official names of this protein?
Hexokinase, BmHK.
What is the protein family that this protein belongs to?
Belongs to the hexokinase family.
Protein: TRUA_BACSV
Sequence: MNNYKLMIQYDGGRYKGWQRLGNGENTIQGKIETVLSEMVGRKIEIIGSGRTDAGVHALGQVANVKLSENFTVKEVKEYLNRYLPHDISVTEVTLVPDRFHSRYNAKDKTYLYKIWNEDYTHPFMRKYSLHIEKKLHIDNMVKASQLFVGEHDFTAFSNAKSKKKTNTRTIHSITIQDNQGFIDIRVCGDGFLYNMVRKMVGTLIEVGLGEKEPEQVLTILESKDRSQAGFADATGLYLEGISF
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NIKR_BRUA2
Sequence: MQRITITIDDDLMAALDRMIEIKGYQNRSEALRDLARTGLQQASLEEGQMEACVGVLSYTYDHSARDLSKKLTNTHHDHHNISVASMHVHLDHDRCLEVSILKGKTDDVRHFADHVKAERHVTHGTLAVLPL
What is the function of this protein?
Transcriptional regulator.
What are the official names of this protein?
Putative nickel-responsive regulator.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory CopG/NikR family.
Protein: CXE18_ARATH
Sequence: MATDSQPNQKLTLPLKTRIALTVISTMTDNAQRPDGTINRRFLRLFDFRAPPNPKPVNIVSTSDFVVDQSRDLWFRLYTPHVSGDKIPVVVFFHGGGFAFLSPNAYPYDNVCRRFARKLPAYVISVNYRLAPEHRYPAQYDDGFDALKYIEENHGSILPANADLSRCFFAGDSAGGNIAHNVAIRICREPRSSFTAVKLIGLISIQPFFGGEERTEAEKQLVGAPLVSPDRTDWCWKAMGLNRDHEAVNVGGPNAVDISGLDYPETMVVVAGFDPLKDWQRSYYEWLKLCGKKATLIEYPNMFHAFYIFPELPEAGQLIMRIKDFVDERVASLSA
What is the function of this protein?
Carboxylesterase acting on esters with varying acyl chain length.
What are the official names of this protein?
Probable carboxylesterase 18, AtCXE18.
What is the protein family that this protein belongs to?
Belongs to the 'GDXG' lipolytic enzyme family.
Protein: RHAS_ECO55
Sequence: MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
What is the function of this protein?
Activates expression of the rhaBAD and rhaT operons.
What are the official names of this protein?
HTH-type transcriptional activator RhaS, L-rhamnose operon regulatory protein RhaS.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPTV1_VOLCA
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTVELDGKVIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLAEIDRYASENVNKLLVGNKSDLTGKKVVDYQAAKAFADEIGIPFLETSAKNATNVEQAFMTMAAEIKNRMASQPVPPKPGGPVVRPTEGKPINNKSSSCC
What is the function of this protein?
Protein transport.  Probably involved in vesicular traffic (By similarity).
What are the official names of this protein?
GTP-binding protein yptV1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ZN219_HUMAN
Sequence: MEGSRPRAPSGHLAPSPPAFDGELDLQRYSNGPAVSAGSLGMGAVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPGPASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSLRAGEGRPNGEGAEPGPGRSFGGFRPLSSALPARARRHRAEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPSSGAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRPPQADASPPYARVPSGETPPSPSQEGEEGSGLSRPGEAGLGGQER
What is the function of this protein?
Transcriptional regulator (PubMed:14621294, PubMed:19549071).  Recognizes and binds 2 copies of the core DNA sequence motif 5'-GGGGG-3' (PubMed:14621294).  Binds to the HMGN1 promoter and may repress HMGN1 expression (PubMed:14621294).  Regulates SNCA expression in primary cortical neurons (PubMed:19549071).  Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with SOX9 (By similarity).  Plays a role in chondrocyte differentiation (By similarity).
What are the official names of this protein?
Zinc finger protein 219.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: H3_PSAMI
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTELRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3, embryonic.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.