PharMolix/UniProtQA huggingface dataset:
Protein: UBIG_SALDC
Sequence: MNTEKPSVAHNVDHNEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYITERSGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIEVEYVQETVEEHAAKHAQQYDVVTCMEMLEHVPDPQSVVHACAQLVKPGGEVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLSWVDETVLKEQHITGLHYNPITNTFKLGPGVDVNYMLHTRAKKA
What is the function of this protein?
O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.
What are the official names of this protein?
Ubiquinone biosynthesis O-methyltransferase, 2-polyprenyl-6-hydroxyphenol methylase, 3-demethylubiquinone 3-O-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
Protein: SYPL2_HUMAN
Sequence: MSSTESAGRTADKSPRQQVDRLLVGLRWRRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGAMVRCNNEAKDVSSIIVAFGYPFRLHRIQYEMPLCDEESSSKTMHLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHNLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANISVLFGFINFFLWAGNCWFVFKETPWHGQGQGQDQDQDQDQGQGPSQESAAEQGAVEKQ
What is the function of this protein?
Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes.
What are the official names of this protein?
Synaptophysin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the synaptophysin/synaptobrevin family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein. Note=Triad junction, the junctional complex between the transverse tubule and the sarcoplasmic reticulum.
Protein: MNTP_BACHK
Sequence: MTFEQLIPLIIMAFALGMDAFSVSLGMGMMALKIRQILYIGVTIGIFHIIMPFIGMVLGRVLSEQYGDIAHFAGAILLIGLGFYIVYSSILENEETRTTPIGISLFVFAFGVSIDSFSVGLSLGIYGAQTIITILLFGFVSMLLAWTGLFIGRHAKGMLGTYGEIVGGIILVGFGLYLLFPI
What is the function of this protein?
Probably functions as a manganese efflux pump.
What are the official names of this protein?
Putative manganese efflux pump MntP.
What is the protein family that this protein belongs to?
Belongs to the MntP (TC 9.B.29) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL35_ECOL5
Sequence: MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TRUA_CLOK5
Sequence: MKNIKLVIEYDGTNYSGWQRQYNAITIQQRLEEAIEKATGEFSPVIGSSRTDAGVHARGFVCNFFTASKIPTSNIKMVLNTLLPEDIAVLDSKEVDSSFHSRYFTTGKEYSYTIVTGDRPPVIGRQYVYYFRRKLDIEKIKNSCEYFIGTHDFSAFKKKGSTARSSIRTIKELTVLKEKNIIKFNIVGDGFLYNMVRIIIGTLLEVGLGRFSIEYVKYILESKDRAKAGKPVPAKGLCLEKVFY
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: NADK_CALS8
Sequence: MIVGVFANFQKELSKEILDKIVSVLKNEKIDWVLMNEKNKDSVKVNFLITIGGDGTLLNVVEKVAKENLPVLGINCGRVGYLTEEVADNIHFAIKKIIDNDYFIEERHLVEAHFKDKIFYALNDICLARSTFNIIDLSLYIDEVFAQEYRSDGIIIATATGSTAYSLSAGGPIVEPQLGVMVVTPICPHSLSSRSLVLGDDRVVKIKSESDEVLVVSDGRVADTLKKGEYLECKISSKKLKLVRLKKKNFYEVLREKIKE
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_MYCBO
Sequence: MTVGLGMPQPPAPTLAPRRATRQLMVGNVGVGSDHPVSVQSMCTTKTHDVNSTLQQIAELTAAGCDIVRVACPRQEDADALAEIARHSQIPVVADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVGEVAKAAGAAGIPIRIGVNAGSLDKRFMEKYGKATPEALVESALWEASLFEEHGFGDIKISVKHNDPVVMVAAYELLAARCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSRGIGDTIRVSLSAPPVEEVKVGNQVLESLNLRPRSLEIVSCPSCGRAQVDVYTLANEVTAGLDGLDVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVRGEVIKTVPEAQIVETLIEEAMRLAAEMGEQAPGATPSGSPIVTVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: TRPB_STAAT
Sequence: MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGGGSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQVQLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERGLAND
What is the function of this protein?
The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
What are the official names of this protein?
Tryptophan synthase beta chain.
What is the protein family that this protein belongs to?
Belongs to the TrpB family.
Protein: HLDE_PELPD
Sequence: MDRKSIESIFNRIRTANCLVIGDLMLDEYLWGKAERISPEAPVQVVDVVREEMRLGGAGNVVNNLVELGAEVTVCSVVGDDDNGQALLEAFGRRGVATDAIFLDATRRTSRKTRVVAAHQQIVRIDRESRVPLSAEVERRVSDWITANAGGFDVILLSDYQKGVLTPGVISATLAAARPGAIPVLVDPKGTDFSRYSGATLLTPNRREAEAASGIAIHDIESLVRAAGVIMERVGLEHLLITRSEEGMSLFSRSAAPMHIPTVAREVFDVSGAGDTVLASLAAGMAAGMEMIEAARLANITAGIAVAKLGTSTVAPAEIINAVALAHSDSDSKIKNRDVLAVLIEAEKARGKRIVFTNGCFDLLHAGHVKYLQKARTLGDLLVLGLNSDASVRRLKGEKRPLIGEQERAHILAALDCIDYVVIFEEDTPLELIAALKPHILAKGGDYTPEGVVGRELVESYGGRVELVSFVDGKSTTNIIERVLERYS
What is the function of this protein?
Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
What are the official names of this protein?
Bifunctional protein HldE.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the cytidylyltransferase family.
Protein: RSMA_HALSA
Sequence: MTAPRDPDALIRRAGRPNPDFDQHFLIDDRVLDRIPTYADGFDRGHVLEIGAGTGALTDRLLSVADRVTAVERDESYASFLREEFADAIAAGDLDVVAGDALAVDLPAFTCAVSNLPYGVASEVTFRLLPAGKPMVLMYQLEFAERMAADPGTSEYGRLSVATQHYADVSIVETVPAAAFDPQPRVESAVVRVTPRDPDYVVADEAFFLSFVKALFTQRRKTTRNAIRNTAHISGLDDPDAVVAAVDDDVLGTRPGSLSPATFAALANVAWGVETAPGPDPQ
What is the function of this protein?
Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle.  May play a critical role in biogenesis of 30S subunits.
What are the official names of this protein?
Probable ribosomal RNA small subunit methyltransferase A, 16S rRNA dimethyladenosine transferase, 16S rRNA dimethylase, S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYA_RHIWR
Sequence: MTSTNDIRRSFLDHFAKEGHELVPSAPLVPHNDPTLMFVNAGMVPFKNVFTGLEKRPYSTATSSQKCVRAGGKHNDLDNVGYTARHHTFFEMLGNFSFGDYFKERAISLAWSLITGTWGIPADRLTVTVFHTDDEAFDLWKKIGMPDSRIIRIPTSDNFWSMGDTGPCGPCSEIFYDHGAHIPGGPPGSPDEDGDRFVEIWNLVFMQYEQVDKETRIDLPRPSIDTGMGLERIAAVLQGVHDNYDTDTFKALIAASGELTRTATNGDFKASHRVIADHLRASGFLVADGVLPANEGRGYVLRRIMRRAMRHAHLLGAAEPLMHRLVPSLVAEMGAAYPELVRAQPLIEETLKLEETRFRQTLANGLRLLDEATGAMKPGDVLPGAVAFKLYDTFGFPYDLTEDALRAQDLGVDRSGFDAAMAEQKAAARAAWKGSGEKASDEVWFDIAEEFGGTEFTGYVSEEGDGQLLAIVKDGQRVAEAKAGDEVVLVTNQTPFYGESGGQMGDAGRITGDDGLEIAVEDTAKPLGRVHAHRGTVVSGSVRTGDALHLVVDGDRRTRIRANHSATHLLHAALRNRLGSHVTQKGSLVAADRFRFDFSHPKALTPEDIAAIEAEVNRHIRENDEVTTRLMTPDAAIEAGAMALFGEKYGDEVRVLSMGKAGRDLGAKSYSVELCGGTHVSALGDIALFKIISESAVSSGVRRIEALTGEAARQWLTQRDEKLKEAAAALKTAPDDVPARIAVLVEERRKLERELAEAKKALALGGGSKAEAAGPEDVAGVKFLPQVVDGLDPKGLRGLVDDAKASLGSGVSVIVAVNDGRASVAAGVTADLVDRISAVDLVKAAVAALGGQGGGGRPDMAQGGGPDGDKAADAVAAVRDALAKVPA
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_RUBXD
Sequence: MISEEQVRHVAELARLGLTDEEVARMGGQLGAILDSIEKIRELDLEGVPPTANPLNLTNVFRPDEPRESLRREEALAVAPETADGMFAVPRID
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MATK_SACOF
Sequence: MQKFEGYSEKQKSRQHYFVYPLLFQEYIYAFAHDYGLNGSEPVEIFGCNNKKFSSILVKRLIIRMYQQNFLINSVNYPNQDRLFDHRNYFYSEFYSQILSEGFGIVVEIPLSLGQLSCPEEKEIPKFQNLQSIHSIFPFLEDKFLHLHYLSHIEIPYPIHLEILVQLLEYRIQDVPSLHLLRFFLHYYSNWNSLITSMKSIFLLKKENQRLFRFLYNSYVSEYEFFLLFLRKQSSCLRLTSSGTFLERIIFSGKMEHFGVMYPGFFRKTIWFFMDPLMHYVRYQGKAILASKGTLLLKKKWKSYLVNFSQYFFYFWTQPQRIRLNQLTNSCFDFLGYLSSVPINTLLVRNQMLENSFLIDTRMKKFNTTVPATPLVGSLSKAQFCTGSGHPISKPVWTDLSDWDILDRFGRICRNLFHYYSGSSKKQTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSVFLEEFFTEEEQVFSLMFTKTIHFSFHGSQSERIWYLDIIRINDLVNPLTLN
What is the function of this protein?
Usually encoded in the trnK tRNA gene intron.  Probably assists in splicing its own and other chloroplast group II introns.
What are the official names of this protein?
Maturase K, Intron maturase.
What is the protein family that this protein belongs to?
Belongs to the intron maturase 2 family. MatK subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: DLTC_BACMK
Sequence: MAEFKEQVLDILEEVCENDIVKENLDVQLFEEGILDSFAVVSLLVEFQERLEIEVSISDFDRDEWATPNMVIKKLEEIR
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS6_DESAL
Sequence: MRRYETIFISDPDLPEDNRATLFEKMQGLIAEHDGYIAFFDEWGARKLAYEVKKKKRGYYVLMDFCAEGSLIAEMERIMRIDDRILKFLTIQTEEEVDLDAVKEQVAKAKAEKEAAQKAAAEKAEAARLEAEKAAEEEAAKAAEAQAKEAPAAEAPAEEAPAAEAPAEAPAEEPAEEPKSDEEDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: Y2012_CERSK
Sequence: MAGHSKWANIQHRKGKQDKLRSKMFSKLAKEITVAAKMGDPDPDKNPRLRLAVKAAKAVSMPKDVIERAIKKSQGGDAEDYSEIRYEGYGPNGIAIIVETMTDNVNRTASNVRSYFTKYGGNLGTTGSVSFMFDRVGEITYKPEAGDADTVMMAAIEAGAEDVESDEEGHWIYCGDTSLNEVSEALEKVLGESEEAKLVWKPQNRTNVDLETAQKLMKLIDALEEDDDVQTVTGNFDIPEDVAAKLDA
What are the official names of this protein?
Probable transcriptional regulatory protein RSKD131_2012.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OCAT2_MOUSE
Sequence: MSEKPKVYQGVRVKMTVKELLQQRRAHQATSGANLSGSSGLHLPDTTMPSSAGLYFEPEPTSSTPSYFQTREFSTCVSCEEIPSCLDQIFESYLQTDTLPEPLLNSAQIAPHYFPESCQVAPFCHNQSLIPGSPSDSSSLSGSFDCSYSPTQLPSYTPENYSSPPSLDSLHSSLPEEGYFCQHWPSHPQYNHSSPATPSSVCYYASCEAEHLDALRTTEFFSYSGMDCADFAPPVATTGDFYKRETSCDACYS
What is the function of this protein?
Transcriptional coactivator that specifically associates with POU2F3.  This complex drives the development of tuft cells, a rare a rare chemosensory cells that coordinate immune and neural functions within mucosal epithelial tissues.
What are the official names of this protein?
POU Class 2 homeobox-associating factor 3, Protein OCA-T2.
What is the protein family that this protein belongs to?
Belongs to the POU2AF family.
Protein: RL19_DESPS
Sequence: MSIIIDRINQEQMRQDHPDFRPGDTVAVHIRIIEGSKERVQLFQGVVIKRQKGTMDASYTVRKISHGVGVEKTFALHNPRIEKIEVITRGRVRRSRLYYLRDLRGKAARIRERSLRR
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: UBID_SHEPC
Sequence: MSFKDLRSFIDHLEANGELKRISYPVDPHLEMTEIADRVLRAKGPALLFENPKNHHMPVLANLFGTPKRVAMALGKDDPLALREVGELLAFLKEPEPPRGFKDAIAKIPMFKQALNMPPKTVRNPPCQQIIKTGDEVDLTQLPIQHCWPGDVAPLVTWGLTITKGPRKSRQNLGIYRQQLLGKNKLIMRWLSHRGGALDFADFKEQFPGERYPVVVALGADPVTILGAVTPVPDSMSEYAFAGLLRGERTEVCKALSCDLEVPATSEIILEGYIDPEELAEEGPYGDHTGYYNETDKFPVFTVTHITQRKDAIYHSTYTGRPPDEPAMLGVALNEVFVPILRKQYPEIVDFYLPPEGCSYRMAVISIRKQYPGHAKRVMMGAWSFLRQFMYTKFIVIVDEDVNCRDWQDVIWAITTRMDPKRDTVMIENTPIDYLDFASPVAGLGSKMGLDATNKWEGETNREWGTPIVMDPKVKQKIDSIWDELGIDDSPTL
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DUT_EHV4
Sequence: MASATNLADNIVVVECSNGWEARAEADGRLLVLINNHTVELSAGLGSAGEFYSVLTDVGVRVACSSGYAIVLAQISGLPHVGREPGNFSNITFTGNLANYYTAYGIVDSGYRGVVKAVQFANGVNTVVPPGCMSLGLVLVKLSTETINVTNINLTENGRSPRVNIFYDYFAPKRDEDAGYDISAQTNATIEPDESYFVELPIVFSSSNPAVTPCIFGRSSMNRRGLIVLPTRWVTGRTCCFFILNINKYPVYITKGQRVAQLVLTEDIDEALIPTNVNYNTPFPTYSPTGAVKHNPTPILWKFTEAFDHDAPSSARSEGGFGSTGL
What is the function of this protein?
Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: PSBI_PANGI
Sequence: MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly.  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein I, PSII-I, PSII 4.8 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the PsbI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: AFTIN_HUMAN
Sequence: MEPDIIRMYSSSPPPLDNGAEDDDDDEFGEFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPSNHFMPIHEFSENVDSLTSFKSIKNGNDKDITAELSAPVKGQSDVLLSTTSKEIISSEMLATSIDGMERPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVVHQNKQLESCNGEKPPCLEILTNGFAVLETVNPQGTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAEEFADFATFSKKERIQLEEIECAVLNDREALTIRENNKINRVNELNSVKEVALGRSLDNKGDTDGEDQVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSGVQSKAWSLVDSADNSEAIRREQCKTEEKLDLLTSKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQSPNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINEDDFGDFGDFGSASGSTPPFVTGTQDSMSDATFEESSEHFPHFSEPGDDFGEFGDINAVSCQEETILTKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLKNGQEGEIGHFDSVPNIQDDCNGFQDSDDFADFSSAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATESHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSKGAVASGHLQESATSVQTALLNRLERIFEACFPSILVPDAEEEVTSLKHLLETSTLPIKTREALPESGELLDVWTELQDIHDAHGLRYQWGGSHSNKKLLSSLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEPTKEPLKPLSAAEKIASIGQTATMSPDMNTCTSDQFQESLPPVQFDWSSSGLTNPLDASGGSTLLNLDFFGPVDDSSSSSSTTIPGVDPELYELTTSKLEISTSSLKVTDAFARLMSTVEKTSTSTRKPKREEHLSEEAIKVIAGLPDLTFMHAKVLMFPATLTPSTSSQEKADG
What is the function of this protein?
Component of clathrin-coated vesicles (PubMed:15758025).  Component of the aftiphilin/p200/gamma-synergin complex, which plays roles in AP1G1/AP-1-mediated protein trafficking including the trafficking of transferrin from early to recycling endosomes, and the membrane trafficking of furin and the lysosomal enzyme cathepsin D between the trans-Golgi network (TGN) and endosomes (PubMed:15758025).
What are the official names of this protein?
Aftiphilin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Co-localizes with AP1G1/AP- 1 in the cytoplasm (PubMed:14665628, PubMed:15758025). Recruited to the perinuclear region by AP1G1/AP-1 (PubMed:15758025).
Protein: VP2_CAV26
Sequence: MHGNGGQPAAGGSESALSREGQPGPSGAAQGQVISNERSPRRYSTRTINGVQATNKFTAVGNPSLQRDPDWYRWNYNHSIAVWLRECSRSHAKICNCGQFRKHWFQECAGLEDRSTQASLEEAILRPLRVQGKRAKRKLDYHYSQPTPNRKKVYKTVRWQDELADREADFTPSEEDGGTTSSDFDGDINFDIGGDSGIVDELLGRPFTTPAPVRIV
What is the function of this protein?
May act as a scaffold protein in virion assembly.  May also play a role in intracellular signaling during viral replication (By similarity).
What are the official names of this protein?
Dual specificity protein phosphatase VP2.
What is the protein family that this protein belongs to?
Belongs to the gyrovirus protein VP2 family.
Protein: MSCL_BORBR
Sequence: MSKATGFIKEFRDFAVKGNAIDLAVGVIIGAAFGKIVDSLVKDVVMPLVNFILGGSVDFSNKFLVLSMPDGYTGPMTYADLTKAGANVLAWGNFITIIINFVLLAFVIFWMVKAIYSARRKEEAAPEAPAAPPEDVTVLREIRDLLKDKQGS
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: BETA_BRUSU
Sequence: MEADFVIIGSGSAGSAMAYRLSENGRYSVIVIEYGVPDVGPLIQMPAALSFPMNMETYDWGFSSEPEPHIGGRSLVTPRGKVLGGSSSINGMVYVRGHACDFDHWSQSGARGWAYADVLPYFKRMENSQGGQEGWRGTNGPLYVQRGKRDNPLFHAFVEAGHQAGFEVTDDYNGEKQEGFGPMEQTIHNGRRWSAANAYLKPALKRPNVKLVKGFARKIVLEGKRAVGVEIEAGRTFSTIRARREVIIAASSINSPKLLMLSGIGPAAHLKEHGIDLVADRPGVGQNLQDHLEVYIQQECTQPITLYSELNLFSKARIGVEWLLFKTGDGATNHFESAAFVRSKAGVEYPDIQYHFLPVAIRYDGKAAAQSHGFQAHVGPMRSKSRGSVTLRSANPREKPVIKFNYMSHEDDWADFRHCVRLTREIFGQAAFDPYRGAEIQPGAHVQTDDEIDNFIREHVESAFHPCGTCKMGAVDDPMAVVDPECRVIGVEGLRVADSSIFPRITNGNLNGPSIMVGEKASDHILGRTPLARSNQEPWINPRWQVSDR
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: RIR2_SCHPO
Sequence: MGLEHLEEFSYPKEHGEEVEYDSEQGVRKIYVKSIKETFNFDNVSEEEKQEGGDYYLGKKEDELDEVVLRPNPHRFVLFPIKYHEIWQFYKKAEASFWTAEEIDLSKDLVDWDNKLNADERYFISTVLAYFAASDGIVNENLLERFSSEVQIPEARCVYGFQIMIENIHSETYSLLLDTYIREPKEKQRHFDAILTMGSIKAKAKWALRWINDEDSTYAIRLVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELICRDEGLHTDFACLMFSHLKHRPGRKVVEAIIVEAVDIEKEYFTDALPVSLLGMNKDLMCQYIEFVADRLLVALGNDKYYNVTNPFDFMENISLAGKTNFFEKKVSDYQIAGVMSGTKRAEKDDHTFTIDEDF
What is the function of this protein?
Provides the precursors necessary for DNA synthesis.  Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
What are the official names of this protein?
Ribonucleoside-diphosphate reductase small chain, Ribonucleotide reductase small subunit.
What is the protein family that this protein belongs to?
Belongs to the ribonucleoside diphosphate reductase small chain family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Localization to the cytoplasm is CSN- and checkpoint-dependent and is required for an efficient DNA damage response.
Protein: YVEF_BACSU
Sequence: MKKPVLKPFASLEIKVDPPITIGETSLGLR
What are the official names of this protein?
Uncharacterized protein YveF.
Protein: CCME2_XANOR
Sequence: MNPQRRRRLWWVLALLLAGGLATTLVSMALQRNVAYLYTPSEVLRGDAGENSRFRLGGMVEKGSFQRASGALEAHFRVTDGDAQLPVSYDRILPDLFREGQAVVATGRMQSGVFVAEDVLAKHDETYMPKEVADKMGSAHRKHDVPAAANQGGALR
What is the function of this protein?
Heme chaperone required for the biogenesis of c-type cytochromes.  Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH.
What are the official names of this protein?
Cytochrome c-type biogenesis protein CcmE 2, Cytochrome c maturation protein E 2, Heme chaperone CcmE 2.
What is the protein family that this protein belongs to?
Belongs to the CcmE/CycJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein; Periplasmic side.
Protein: VP3_BTV10
Sequence: MAAQNEQRPERIKTTPYLEGDVLSSDSGPLLSVFALQEIMQKVRQVQADYMTATREVDFTVPDVQKILDDIKTLAAEQVYKIVKVPSISFRHIVMQSRDRVLRVDTYYEEMSQVGDVITEDEPEKFYSTIIKKVRFIRGKGSFILHDIPTRDHRGMEVAEPEVLGVEFKNVLPVLTAEHRAMIQNALDGSIIENGNVATRDVDVFIGACSEPIYRIYNRLQGYIEAVQLQELRNSIGWLERLGQRKRITYSQEVLTDFRRQDTIWVLALQLPVNPQVVWDVPRSSIANLIMNIATCLPTGEYIAPNPRISSITLTQRITTTGPFAILTGSTPTAQQLNDVRKIYLALMFPGQIVLDLKIDPGERMDPAVRMVAGVVGHLLFTAGGRFTNLTQNMARQLDIALNDYLLYMYNTRVQVNYGPTGEPLDFQIGRNQYDCNVFRADFATGTGYNGWATIDVEYRDPAPYVHAQRYIRYCGIDSRELINPTTYGIGMTYHCYNEMLRMLVAAGRDSEAAYFRSMLPFHMVRFARINQIINEDLHSVFSLPDDMFNALLPDLIAGAHQNADPVVLDVSWISLWFAFNRSFEPTHRNEMLEIAPLIESVYASELSVMKVDMRHLSLMQRRFPDVLIQARPSHFWKAVLNDSPEAVKAVMNLSHSHNFINIRDMMRWVLLPSLQPSLKLVLEEEAWAAANDFEDLMLTDQVYMHRDMLPEPRLDDIERFRQEGFYYTNMLEAPPEIDRVVQYTYEIARLQANMGQFRAALRRIMDDDDWVRFGGVLRTVRVKFFDARPPDDILQGLPFSYDTNEKGGLSYATIKYATETTIFYLIYNVEFSNTPDSLVLINPTYTMTKVFINKRIVERVRVGQILAVLNRRFVAYKGKMRIMDITQSLKMGTKLAAPTV
What is the function of this protein?
The VP3 protein is one of the five proteins (with VP1, VP4, VP6 and VP7) which form the inner capsid of the virus.
What are the official names of this protein?
Core protein VP3, Major inner capsid protein.
What is the protein family that this protein belongs to?
Belongs to the orbivirus VP3 family.
What are the subcellular locations of this protein?
Virion.