PharMolix/UniProtQA huggingface dataset:
Protein: TXA2_LATGE
Sequence: MLKLICIVFLVTVLTFVVGEDTLDPAEYGCPSDVDMAELTEKNEVCLRCEDFHKEGVAFTLCKTNCFTTEYYKNCVKDLEEAGKETEE
What is the function of this protein?
May increase the toxicity of alpha-latrotoxin and/or other venom components.  Is non-toxic to mice and to the cockroach Periplaneta americana.
What are the official names of this protein?
Alpha-latrotoxin associated low molecular weight protein 2, Alpha-latrotoxin-associated LMWP2, Latrodectin-2.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
What are the subcellular locations of this protein?
Secreted.
Protein: YO14A_YEAST
Sequence: MHAHFDRKILNFKPVTVNVIRYCLQFSFKAVTFLLI
What are the official names of this protein?
Putative uncharacterized protein YOR314W-A.
Protein: LGR5_MOUSE
Sequence: MDTSCVHMLLSLLALLQLVAAGSSPGPDAIPRGCPSHCHCELDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLPASLLHRLCFLEELRLAGNALTHIPKGAFTGLHSLKVLMLQNNQLRQVPEEALQNLRSLQSLRLDANHISYVPPSCFSGLHSLRHLWLDDNALTDVPVQAFRSLSALQAMTLALNKIHHIADYAFGNLSSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDEFPTAIKTLSNLKELGFHSNNIRSIPERAFVGNPSLITIHFYDNPIQFVGVSAFQHLPELRTLTLNGASHITEFPHLTGTATLESLTLTGAKISSLPQAVCDQLPNLQVLDLSYNLLEDLPSLSGCQKLQKIDLRHNEIYEIKGSTFQQLFNLRSLNLAWNKIAIIHPNAFSTLPSLIKLDLSSNLLSSFPVTGLHGLTHLKLTGNRALQSLIPSANFPELKIIEMPSAYQCCAFGGCENVYKISNQWNKDDGNSVDDLHKKDAGLFQVQDERDLEDFLLDFEEDLKALHSVQCSPSPGPFKPCEHLFGSWLIRIGVWTTAVLALSCNALVALTVFRTPLYISSIKLLIGVIAVVDILMGVSSAVLAAVDAFTFGRFAQHGAWWEDGIGCQIVGFLSIFASESSIFLLTLAALERGFSVKCSSKFEVKAPLFSLRAIVLLCVLLALTIATIPLLGGSKYNASPLCLPLPFGEPSTTGYMVALVLLNSLCFLIMTIAYTKLYCSLEKGELENLWDCSMVKHIALLLFANCILYCPVAFLSFSSLLNLTFISPDVIKFILLVIVPLPSCLNPLLYIVFNPHFKEDMGSLGKHTRFWMRSKHASLLSINSDDVEKRSCESTQALVSFTHASIAYDLPSTSGASPAYPMTESCHLSSVAFVPCL
What is the function of this protein?
Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle.  Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes.  In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal.  Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
What are the official names of this protein?
Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, Orphan G-protein coupled receptor FEX.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Note=Rapidly and constitutively internalized to the trans-Golgi network at steady state.
Protein: PGK_ACIB3
Sequence: MNFQRMTDLNLAGKRVLIREDLNVPVKNGVITSDARLRAALPTIKAALEKGAAVMVFSHLGRPVEGEPKPEQSLAPVAAYLTEALGQEVKLFTDYLDGVEVEAGQVVLLENVRFNPGEKKNNPELAQKYAALCDVFVMDAFGTAHRAEASTEGVARFAPVAAAGPLLAAELDALGRAMQTPEKPMVAIVAGSKVSTKLDVLNSLSGICDQLIVGGGIANTFLAAAGYNVGKSLYEADLVETAKQIAAKVSVPLPTDVVVADASQINFEDFLGSLAAAQAVIKKVEDVTANDMILDVGPETAKAFANILTTSKTILWNGPVGVFEVDQFGEGTKALSLAVAQSDAFSIAGGGDTLAAIDKYNVADQIGYISTGGGAFLEFVEGKTLPAVAVLLERA
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TERA_ALCSP
Sequence: MVFYGQPRNEDGSISFSAEGTNSVFTVDLSRLKPDVQKVAFTVTCDGSHTVSSLNHLSIQIESGNTSLISGQVELSGRQEAALILGEVYRRNGDWKFVFIAQGFNGGLKPLAEYYGVNVADEPAPVTPPPAPPAPPKVSLSKVSLTKEKPAISLAKKANFGEIRINLNWHRGSGSGGLLGGMFGSNKAIDLDLGAFVELADGYKSVVQALGNAFGNYHSEPYVQMQGDDRTGEALDGEWLHINGREWKEIRQVLIYAFIYQGVPSWDKTDGVVTLHVPEQPPIESRLTEGDNKRTLCAIARLVNENGSIRVERINQYFRGQEEMDRAFGWGFRWSRGSK
What is the function of this protein?
Not yet known.
What are the official names of this protein?
Tellurium resistance protein TerA.
Protein: LEUC_HALH5
Sequence: MAPKTIIEKIWDAHTVIGEEGKPSLLYIDLHMVHEVTSPQAFEGLRLAGRPVRRPDLTFATMDHNVPTVDRFNIQDQIARKQIETLEANCKEFGIEIAGLDSPNNGIVHVIGPELGLTQPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLWQSKPKTMEVRVTGELAPSVSAKDIILAVIAKYGVDFGTGHVIEFTGEAIRSLSMEERMTICNMSIEAGAKAGLISPDSVTFEYLRGRPNAPKGEAFDVAIQQWEALATDAGAVYDRVLTMNASEIEPMVTWGTNPAQGTGVSQVVPSPDDAKDENERRAIKQSLAYMGLEPGTPITEIAIQHVFIGSCTNSRLSDLRTAAELIKGRKVADGVRALVVPGSQQVKRAAEKEGLDEIFKEAGFEWRDSGCSMCLGMNPDTVPEGERCASTSNRNFEGRQGKGARTHLVSPQMAAAAAIAGHFVDVRTFQSEPQTV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: CYHR1_DROME
Sequence: MSVESSSSAVQQPPSSSNLPLLGDNQAVATTSSASSASSSSTSSSSSSVGGGNVVGVPLDTQGSGEPPAKKQLLDGGGGGATSSSGSSLLSSAAAASGMHEKLAHRISNALCCAVCLDLPKTAMYQCQMGHLMCAACFTHLLADGRLRDQIATCPNCRVEISKSTASRNLAVEKAASELPSECQFCNKEFPYKSLERHEQHECQERPTKCKYHRIGCQWRGPYHETNEHERNCLHPQKSGYEVMAALEAHDDRIKEEKKMFNTLIDLLSYEKIIFNDLQMKPYRTDEYVHKLFYETARFSAFNQQWVVKARINNSQRDPHQSNERTITYQLILKTKTSTPMSIHFFALKGPFSDMKVSTQIYKHEFTETSTESEYYVLPLPDGVGGSGSSECNRMLANKGINFRLLMFLLNK
What are the official names of this protein?
Zinc finger TRAF-type-containing protein 1 homolog, Cysteine and histidine-rich protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ZFTRAF1 family.
Protein: ZAPC_FERBD
Sequence: MYITPEPCWAWMYHHDEDKLALELGEDWLFLSPFSARHLIPDSLHGAAFSAQHADYYNDVLDRLRKQLPNSAPEVVQIALNLTAAHFFSLPMMPKSWFFQTSAHIAYACNGKLVELDTGSERARFAVVDGGEQSSLLMLLEQSLALGNKKTMKQFELIKVMNDRLSPCQSLKHRRIVAA
What is the function of this protein?
Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ.  Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ.
What are the official names of this protein?
Cell division protein ZapC.
What is the protein family that this protein belongs to?
Belongs to the ZapC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS8_BIFA0
Sequence: MTMTDPIADMLTRLRNASAAKHETVDMPYSKFKKNIAEILKREGYIADFTAKEARVGQTLEVTLKYGPHGERSIQGIKRVSKPGLRRYAKSDALPMPLGGLGIAIISTSSGLLTQKECLDRGIGGEIVAYVW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: NIP1_NICAL
Sequence: MAKKDGNQEEEISQMEEGNIHSASNSDSNVGFCSSVSVVVILQKLIAEAIGTYFVIFAGCGSVAVNKIYGSVTFPGICVTWGLIVMVMVYTVGYISGAHFNPAVTITFSIFGRFPWKQVPLYIIAQLMGSILASGTLALLFDVTPQAYFGTVPVGSNGQSLAIEIIISFLLMFVISGVATDDRAIGQVAGIAVGMTITLNVFVAGPISGASMNPARSIGPAIVKHVYTGLWVYVVGPIIGTLAGAFVYNLIRSTDKPLRELAKSASSLRS
What is the function of this protein?
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
What are the official names of this protein?
Probable aquaporin NIP-type, Pollen-specific membrane integral protein.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC 1.A.8.12) subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: IDLC_DROME
Sequence: MEELDITSVGQFQTLVRYNNPVLVVKHPDKKGGAPLTEIEMKRPQTAGALLDTKRETEEILNSILPPRCWEEDGQLWQQSVSSTPATRQDVINLQEMLDTRLQQTQARETGICPVRRELYSQCFDEIIRQVTINCSERGLLLLRIRDEIAMSMEAYETLYCSSVAFGMRKALQAHEEKEMLRDRVKTLELDKEALEEIIADMKLKQEQAERRNAELRASEEKKFTEEITFLKKTNAQLKAQLEGITAPKK
What is the function of this protein?
May play a dynamic role in flagellar motility.
What are the official names of this protein?
Putative inner dynein arm light chain, axonemal.
What is the protein family that this protein belongs to?
Belongs to the inner dynein arm light chain family.
What are the subcellular locations of this protein?
Cell projection, cilium. Dynein axonemal particle.
Protein: SYC_SACD2
Sequence: MSLTVYNTRTRKKEPFVPVNPQSIKMYVCGPTVYNLVHIGNARPVVVFDVLFRVLKTLYPEVVYARNITDIDDKIMKAAKENGESISALTARFTEAYIEDMAALHNLPPSIAPKATAHIEPMIAMVAALVEKGHAYEADGHVLFDVQSMKNYGKLSNRALEDMLDGARVEVADYKRYAGDFVLWKPSADDEPGWASPWGRGRPGWHLECSAMIETHLGNTIDIHGGGRDLIFPHHENELAQSECAHGGEEYVRYWMHNGYVNIDGEKMSKSLGNFRTVRDLLQQYHGETIRFALLSAQYRSELDFSVSLLDQSKAGLDTLYGALKNAPATSTDAVDLSDNAGYLALLDDLNTPQVIAELHRLAKIVNKNEGQEAAIAAAQLQALGGLLGLLQQEPEAWFKATTSGSSELSAEDIEQLIVERKDAKLAKNYARADEIRKELTEKGIALEDSASGTSWKRI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTQC_EUBLI
Sequence: MADWKNLTQAVGDLEEDDVMEILNDFVATNPTEAEAEEAVAACQAGMAVVGDLFEEGEYFVGDLIFAGELLTEAINVLKPVLGSGDTAVAGTILIGTAHGDLHDIGKNIFRSMAEAAGFQVTDLGIDVAIDTFVEKAKEIKPDIIGISGVLTLAIDSMKETSDALKAAGVDSKLIIGGNPVTKEACEYVGADDFTTNAAEGVKICQAWVG
What is the function of this protein?
Involved in the degradation of the quaternary amines L-proline betaine and L-carnitine (PubMed:31341018, PubMed:32571881).  Component of a corrinoid-dependent methyltransferase system that transfers a methyl group from L-proline betaine or L-carnitine to tetrahydrofolate (THF), forming methyl-THF, a key intermediate in the Wood-Ljungdahl acetogenesis pathway (PubMed:31341018, PubMed:32571881).  Acts as a methyl group carrier between MtpB or MtcB, and MtqA (PubMed:31341018, PubMed:32571881).  A methyl group from L-proline betaine or L-carnitine is first transferred to the corrinoid prosthetic group of MtqC by MtpB or MtcB, respectively, and then transferred from MtqC to THF by MtqA (PubMed:31341018, PubMed:32571881).
What are the official names of this protein?
Quaternary-amine-specific corrinoid protein, Corrinoid protein MtqC.
What is the protein family that this protein belongs to?
Belongs to the methylamine corrinoid protein family.
Protein: IL1BP_VACCW
Sequence: MSILPVIFLSIFFYSSFVQTFNAPECIDKGQYFASFMELENEPVILPCPQINTLSSGYNILDILWEKRGADNDRIIPIDNGSNMLILNPTQSDSGIYICITTNETYCDMMSLNLTIVSVSESNIDLISYPQIVNERSTGEMVCPNINAFIASNVNADIIWSGHRRLRNKRLKQRTPGIITIEDVRKNDAGYYTCVLEYIYGGKTYNVTRIVKLEVRDKIIPSTMQLPDGIVTSIGSNLTIACRVSLRPPTTDADVFWISNGMYYEEDDGDGNGRISVANKIYMTDKRRVITSRLNINPVKEEDATTFTCMAFTIPSISKTVTVSIT
What is the function of this protein?
May reduce the host inflammatory response by interacting with inteleukin-1 beta (Il1b) and thus decreasing the association between IL1B and its cellular receptor.
What are the official names of this protein?
Interleukin-1-binding protein, Protein B15.
What is the protein family that this protein belongs to?
Belongs to the interleukin-1 receptor family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL25_SHEB9
Sequence: MSYTIQAQTRTEIGKGSSRRLRHAGKVPAVIYGQGKEPVSIVFDHKDIINIQANADFYTSTLTIVVDGKEVGVRAQAMQRHVFKPLIEHVDFVYA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RS14_LEUMM
Sequence: MAKKSKIAKAQKREALVAKYADKRAALKAAGDYIGLAALPKDSSPVRVHNRDWIDGRPHAYMREFGMSRLNFRQLAHKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: YIDD_BACC2
Sequence: MKQIFIGIIRFYQKFISPMTPPTCRFYPTCSHYGLEAFQKHGALKGFWLTCKRILKCHPFHPGGFDPVPDKKDDKVNS
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PUR9_LACPL
Sequence: MTKRALLSVSDKQGLTDFAKGLVALDYELISTGGTKKALEAADIPVIGIEEVTGFPEMLDGRVKTLHPKVHAGLLARRDLPAHMAQLKAAGIQPIDMVVVNLYPFKATIQQPDVTQAEAIEQIDIGGPSMLRSAAKNFAAVLPIVDPADYEQILADLQTDAVTPALRQRLAAKVFQHTAAYDALIAQYLTTEEFPEKLTLTYDKKQALRYGENSHQKAAFYENALPTHFSITGAKQIHGKELSYNNIKDADAALRMVSEYQQPAVVAMKHMNPCGVGLGTTIEAAWDKAYEADSISIFGGIIALNRPVDLATAEKMHALFLEIIIAPSFDDDAFAILAKKKNLRLMTVDFEQTHTADKFETISVGGGLLRQEVDAAFETPADFTVVTVTQPTPAQLKALAFGQQVVKHVKSNAVVVTTADRTLGIGSGQMNRIDSTKIAIGKAMKQAGYENAILASDAFFPMDDCVEYAAQHGIRAIVQPGGSIRDKDSIAMADRYGIAMVTTGVRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: TRUB_CHLT2
Sequence: MELATESIEGVLLVDKPQGRTSFSLIRSLVRLIGVKKIGHAGTLDPFATGVMVMLIGRKFTRLSDIMLFEDKEYAAVAHLGTTTDTYDCDGKIVGRSKKVPTMDEVLTCTSYFQGEIQQVPPMFSAKKVQGKKLYEYARQGLSIERRFATVTVNLRLVKYEYPRLHFVVQCSKGTYIRSIAHELGNMLGCGAYLEELRRLRSGSFSIDQCIDGNLLDEPEFNVSPYLRDANGLILQPAPVL
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: YQI2_CAEEL
Sequence: MVRYSKLAFRQLVRVYDVDVCFTPMIYAKNFIESEKCRSSELSVCEGDSPLIVQFATDDPFVLSEAAEMVYKCSTGVDLNCGCPKHDVRSKGFGSALLSKPELLADMVRQTRARIPDPDFSVSLKIRINHDIEKTVDLCRKAEAAGVTHLTVHGRTPSQRAEPIDIQALRIVKDSVSVPIIANGGITTREEALFLAEQTGVDGIMAANGLLDNPALFAGHEHTPSDCVENFMRLSREYGLDWLLYHQHLQYMLRPVFSAQQRRVFNELNGRLAIDHFLNNLLDI
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
What are the official names of this protein?
Uncharacterized tRNA-dihydrouridine synthase-like protein C45G9.2.
What is the protein family that this protein belongs to?
Belongs to the Dus family.
Protein: QUEC_BURO0
Sequence: MIRTDAKDGALVLFSGGQDSATCVAWALERYQTVETLGFDYGQRHRVELECREGVREALKHRFPAWSDRLGDDHMIDLSVLGAISDTAMTRTIEIETTANGLPNTFVPGRNLMFMTIAAAIAYRRGLRVLVGGMCETDFSGYPDCRDDTMKALQVALNLGMDTRMVLETPLMWLDKAQTWQLAEQLGGEALVELIRVETHTCYVGERAELHDWGFGCGECPACKLRKRGYEAYLKGERVTEAPL
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: MGSA_CARHZ
Sequence: MMKVALIAHDDKKDDLLAFVKTHREFFARHELFATGTTGKIISENTGLTVHRFLSGPLGGDQQIGAMVAAGEIKLVIFFRDPLTAQPHEPDITALLRVCDVHNVPIATNWSSAELFLRALN
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: PCNA_HALLT
Sequence: MFKAIVGASTLQDALDSVSVLVDECKIRLNDEELSIRAVDPANVGMVDLTLEAAAFESYEADGGVIGVNLARLEDIAGMANSGDLIHLELNEETRKLHIEIDGLSYTLALIDPDSIRQEPDIPDLDLASEIVVEGAQINRGITAADMVSDHIRLRVDETDEAFFIEAEGDTDDVDLRLAREDLIALTAGPADSLFSLDYLKDMNKAIPSDAEVTIELGEEFPVKLHYGFAEGLGHVTFMLAPRIQSD
What is the function of this protein?
Sliding clamp subunit that acts as a moving platform for DNA processing.  Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
What are the official names of this protein?
DNA polymerase sliding clamp, Proliferating cell nuclear antigen homolog, PCNA.
What is the protein family that this protein belongs to?
Belongs to the PCNA family.
Protein: MANA1_BACSU
Sequence: MTTEPLFFKPVFKERIWGGTALADFGYTIPSQRTGECWAFAAHQNGQSVVQNGMYKGFTLSELWEHHRHLFGQLEGDRFPLLTKILDADQDLSVQVHPNDEYANIHENGELGKTECWYIIDCQKDAEIIYGHNATTKEELTTMIERGEWDELLRRVKVKPGDFFYVPSGTVHAIGKGILALETQQNSDTTYRLYDYDRKDAEGKLRELHLKKSIEVIEVPSIPERHTVHHEQIEDLLTTTLIECAYFSVGKWNLSGSASLKQQKPFLLISVIEGEGRMISGEYVYPFKKGDHMLLPYGLGEFKLEGYAECIVSHL
What are the official names of this protein?
Mannose-6-phosphate isomerase ManA, Phosphohexomutase, Phosphomannose isomerase, PMI.
What is the protein family that this protein belongs to?
Belongs to the mannose-6-phosphate isomerase type 1 family.
Protein: BIOD_BACHK
Sequence: MSGFFITATDTEVGKTVVAGALAGVFRELGYNIGVYKALQSGHVASNPEGDAARLKVLSGVPTKEDEICPYSIEEPLAPRLAMKRAGRAVTLKDIIHHYNERLKEFNSLFVEGAGGLAVPYTEDALVIDFAKELQLPLIVVARPTLGTVNHTVLTIAYAKANGLTVAGVILSGCKECEMERVQENKVMIEELSGVPVLGLLPFFEGEFTKEEVLESAKEYIMISKLEEFIRNESTVAHTSSN
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SHO1_CANDC
Sequence: MGFSLLNFTGDPFAISTVSFGIMSWVVAIAGAASSKQQTFPHFSWWGISYQIVIILIIFVLYANNNIELYKFTLVGLVSIAFIYTTNSTNNLIYNSNSPGNLCCAAGCILLSILNLIWILYFGGHPESPTNQFIDSFSIRGQGHEQLGSGSHNHNHNLNNANTNTNTNMPLGGGNGIIGKSELSPYDDRFASPINISGGTNQPTSESLRLASVGQMGNGPFSNTTGNPNLQQPLTGSFGGSTNHTPTNANTNTNTTTTNNNNNNTGYMTSSHLTGLENFSSPNVPNNGIGLTRDLTHNSNSLNNNSHNGATGSINNSNNTNKRNTIYTDSETGTGITFRYKAKALYSYDANPDDINEISFVKDEILEVDDIDGKWWQARRANGQVGICPSNYVKLLDT
What is the function of this protein?
Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.
What are the official names of this protein?
High osmolarity signaling protein SHO1, Osmosensor SHO1.
What is the protein family that this protein belongs to?
Belongs to the SHO1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PRMA_SALTY
Sequence: MPWIQLKLNTTGANAEELSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMKDVVAILEQHPLLGAGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDIPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDGLDLNGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEAMKADVVVANILAGPLRELAPLISVLPVEGGLLGLSGILASQAESVCDAYAELFTLDPVVEKEEWCRITGRKK
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK24_PHATC
Sequence: MPQKQKVNVKIGDSVTVISGFHKNETGEVLKINRKNGKIIVKGINFKFKHVKPTTENEIGEIKQFEAPLHHSNVKLNLKKVL
What is the function of this protein?
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L24, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SYS_PHOLL
Sequence: MLDPNILRNELGAVAEKLARRGYTLDVDTLRKQEERRKVLQVETETLQAERNSRSKAIGAAKARGEDIDPLRQEVNQLGEKLDTAKAELEKLQAEIRDLALSIPNIPDDSVPVGKDENDNLEVSRWGEPGKYDFEIQDHVSLGELTNGLDFAAAVKLTGSRFVVMKGQIARLHRALAQFMLNLHTEQHGYLETYVPYLVNHETLYGTGQLPKFGEDLFHTKPLEEEAESHYALIPTAEVPITNLVRGDILDENELPLKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQIVHPDESMDALEALTGHAEKVLQLLNLPYRKVLLCTGDMGFSACKTYDLEVWLPAQNTYREISSCSNMWDFQARRMQARFRGKEDKKTQLLHTLNGSGLAVGRTLVAVMENYQQADGRIEIPEVLRPYMGGLEYIG
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DTD_BACC2
Sequence: MRVVLQRSKKASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKISNLRIFEDESGKMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FIBR2_HEDJA
Sequence: ISGTSMSCPHVAGRAYVLDTSLRVYLLDTGLR
What is the function of this protein?
Serine protease.  Has fibrinolytic and fibrinogenolytic but no plasminogenolytic activity.  Cleaves after Arg and Lys residues.  Cleaves fibrinogen alpha chain, beta chain and gamma chain in that order.
What are the official names of this protein?
Fibrinolytic enzyme 2, NJF-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
Protein: RCF1_TALSN
Sequence: MADQADLLESPQFEEETSMQKFKRRLKEEPLIPLGCAATCYALYRAYRSGKAKDSVEMNRMFRARIYAQFFTLLAVVAGGMYYKTERKQRREFERKVEERKAQEKRDAWLRELEAREKEDKGWRERHAAVSEAANNPVGVSAVVAGKKEEEEKGVDGNVNQAPQEEGGVKRGTGILDAVKALVRGKKD
What is the function of this protein?
Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes.
What are the official names of this protein?
Respiratory supercomplex factor 1, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the RCF1 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: PEX8_PICAN
Sequence: MQPWYHKLGRQGRQLAEQWQTDAEPWGVATPTPLDYLFDELTAPKPSTTPDKVLSYLAYYYPKLKNENNVELLTLCFLRCPLFFNDAQLVSFSDNYRVIECFKYIMDKKFQISQPTLPFYRFYNALFGALAKVVADSACAWKVVPVAVGCLLSVDSRNDYDRYPEHFQLIATVDAKLVDMAAHTLERSMDGPLSNDLLCLNVVALSCVQDKLVDSQLLRILRVRSDILKILTELTFNSPYGLDNGRLLTKSNANTPIVVRHLNRISFLFTKLTSIHPKIVLLADDLDLILNRIQTFSESVLSIPNPSETQWSTLRVVLFAQVMMFEGIMARFFQINNHSLNSTVLPTLCRKILTTLFNFNFVVDRIGTGGFESYNFVYASCLSTLTSYDIPTAETLIKCWTSSVAFKKVDNSATERGKLLFDLQFIENVVNLVSDSLKFEFIIPIVQDLIGNAQDQAVLESAHSVMLKYFTSVDTYNEAQLVDYTNNVKHVGAQLIDYLTLSLDQFPARLSLSQVGIIVETLAKITFPDTAVHECDPELYRELLLLVYNRCLVATSEELPNVQAPPKTRHGAFTSLLIRILPLIPFDEYQSWLERTLSLAFRTVGDERTYLLDLLWDSILGTNRHYPQKGYVGIQWWYEHVNESQEKAKL
What is the function of this protein?
Essential for peroxisome biogenesis.  May play a role in triggering the protein import competence of individual peroxisomes.  It may interact with PEX10.
What are the official names of this protein?
Peroxisomal biogenesis factor 8, Peroxin-8, Peroxisomal protein PER1.
What are the subcellular locations of this protein?
Peroxisome matrix.