PharMolix/UniProtQA huggingface dataset:
Protein: FICD_DROVI
Sequence: MAKAKAKQEPQQQRQTLQATYRFVLFFIAGSLAAFAFHALTSSTGSLMGWRLRLHHLPTAHYLQTRDEFAVYSVDELNAFKEFYDKSISDSVGASFTEAEQTNIKEAMGALRLAQEMYMAGKDDKAARLFEHALALAPKHPEVLLRYGEFLEHNQRNIVLADQYYFQALCISPSNSEALANRQRTADVVQTLDERRLISLDEKRDALSAIHEANSALRRAKKEAYFQHIYHSVGIEGNTMTLAQTRSVLETRMAVDGKSIDEHNEILGMDLAMKYINASLVQKLEITLKDILELHRRVLGHVDPIEGGEFRRNQVYVGGHVPPGPGDLAILMQRFEHWLNSEHSSSLHPVNYAALAHYKLVHIHPFVDGNGRTSRLLMNTLLMRAGYPPVIIPKQQRSKYYHFLKLANEGDIRPFVRFIADCTEKTLDLYLWATSDLPQQIPMLIQTENEGHVLAQLQPHIAQSIPELHESGSGSGSGADPIRVP
What is the function of this protein?
Protein that can both mediate the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins (AMPylation), and the removal of the same modification from target proteins (de-AMPylation), depending on the context (By similarity).  The side chain of Glu-236 determines which of the two opposing activities (AMPylase or de-AMPylase) will take place (By similarity).  Acts as a key regulator of the unfolded protein response (UPR) by mediating AMPylation or de-AMPylation of Hsc70-3/BiP.  In unstressed cells, acts as an adenylyltransferase by mediating AMPylation of Hsc70-3/BiP at 'Thr-518', thereby inactivating it.  In response to endoplasmic reticulum stress, acts as a phosphodiesterase by mediating removal of ATP (de-AMPylation) from Hsc70-3/BiP at 'Thr-518', leading to restore HSPA5/BiP activity (By similarity).
What are the official names of this protein?
Protein adenylyltransferase Fic, De-AMPylase Fic.
What is the protein family that this protein belongs to?
Belongs to the fic family.
What are the subcellular locations of this protein?
Membrane; Single- pass membrane protein.
Protein: LPXK_VEREI
Sequence: MGALRPQPPRMPAGHVAPAYWQKRGLAAWALWPLAQLYRALVAARRGLYRAGWLKAQHPGRPVIVVGNVIAGGAGKTPVVIALARHLQARGLRVGVIARGHGRSRRDCRAVLPDSPASAVGDEPALIARHFANGPAVPVFVARRRISAARALLAAHPDTDVLLCDDGLQHLALRRDLEICVFNDQGLGNGFLQPAGPLREPWPRSVDFVLHAGAAPGGSPAPAFGVQRSLAPCALRSDGAAVPLARLQGQPLHALAAVARPGEFFAMLQARGLTLAHTEALPDHYDLQRWERMTDPRLTLICTEKDAVKLWPLHPDALAVPLVLHIDPGFFAALDAWLPARRAMPEIAPGSDAAAIIAGTEPTLPENHRPMDPKLLQLLVCPVTKGPLRYDRAAQELISRSARLAYPVRDGIPVLLENEARPLTDEELEQ
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the UPF0434 family.
Protein: MNHB1_STAS1
Sequence: MNRQKNNLIFQYSAVVIFFLIVMFGLSLFLAGHYTPGGGFVGGLLLSSALVIITVAFDIKTMRKIFPWDFKILIGIGLLFCLATPMASWFYNKNFFTHTPFEIPLGILPPMEMHTATFFDLGVMCAVVGTVMTIILSIGENE
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit B1, Mnh complex subunit B1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OGG1_SULIL
Sequence: MLRSLVQNPRVRARVLERVDEFRLNNLSNEEVWFRELTLCLLTANSSFISAYQALNCLGDKIYYANEEVIRSILKSCKYRFYNLKAKYIIMAREKVYGKLKEEITPLADSDQQLAREKLLNIKGIGMKEASHFLRNVGYFDLAIIDRHLIDFMRRIGAIGETNVKHLSKSRYISLESVLKSIALNLNISVGILDLFIWYKETNTIVK
What is the function of this protein?
Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA.  Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).
What are the official names of this protein?
8-oxoguanine DNA glycosylase/AP lyase.
What is the protein family that this protein belongs to?
Belongs to the type-2 OGG1 family.
Protein: RL32_PSET1
Sequence: MAVQKSKKSRARRGMRRSHDAISGPSLTVDQTSGETHRRHHVTADGYYKGVQVISK
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: FRS1L_HUMAN
Sequence: MARPPRQHPGVWASLLLLLLTGPAACAASPADDGAGPGGRGPRGRARGDTGADEAVPRHDSSYGTFAGEFYDLRYLSEEGYPFPTAPPVDPFAKIKVDDCGKTKGCFRYGKPGCNAETCDYFLSYRMIGADVEFELSADTDGWVAVGFSSDKKMGGDDVMACVHDDNGRVRIQHFYNVGQWAKEIQRNPARDEEGVFENNRVTCRFKRPVNVPRDETIVDLHLSWYYLFAWGPAIQGSITRHDIDSPPASERVVSIYKYEDIFMPSAAYQTFSSPFCLLLIVALTFYLLMGTP
What is the function of this protein?
Important modulator of glutamate signaling pathway.
What are the official names of this protein?
DOMON domain-containing protein FRRS1L, Brain protein CG-6, Ferric-chelate reductase 1-like protein.
What are the subcellular locations of this protein?
Cell membrane. Synapse.
Protein: ATPE_SYNE7
Sequence: MSLTVRVIAPDRTVWDAPAQEVILPSTTGQLGILPGHAPLLSALDTGVLRVRADKEWLAIAVLGGFAEVENNEVTVLVNAAERGDKIDLEEARAAFSQADERLKGVKEDDRQGKFQATQAYRRARARLQAAGGLVSV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein.
Protein: RL29_ALIF1
Sequence: MKAQDLREKNVEELNEELLNLLREQFNLRMQAATGQLQQTHTLKAVRRDIARVKTLLNEKAGA
What are the official names of this protein?
50S ribosomal protein L29.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
Protein: RS4E_ARCFU
Sequence: MIELHQKRLSAPKTYKIPRKVSKWVVKPSPGPHNKEAIPLLVLVRDFLELADTGREARRIISAGEILVDGVVRKDYKFPVGLFDVVTIPKLEKSYRILFDEKGRYIPKEVEDADLKLYKITNKTLVRGGKVQLNLFDGTNILGSNDYKTKDSILLRIPEKEVVDHLKFEEGALVMITGGTHAGEIGRIKSYKIVRSSAPNLVTVEGEERDITTIEDYVFVVGKKDSDKPVIDLGV
What are the official names of this protein?
30S ribosomal protein S4e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS4 family.
Protein: MACIR_PONAB
Sequence: MEVDINGESRSTLTTLPFPGAEANSPGKAEAEKPRCSSTPCSPMRRTVSGYQILHMDSNYLVGFTTGEELLKLAQKCTGGEESKAEAMPSLRSKQLDAGLARSSRLYKTRSRYYQPYEIPAVNGRRRRRMPSSGDKCTKSLPYEPYKALHGPLPLCLLKGKRAHSKSLDYLNLDKMIKEPADTEVLQYQLQHLTLRGGRVFARNNT
What is the function of this protein?
Regulates the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages.  The regulation of macrophage function is, due at least in part, to its ability to inhibit glycolysis.  May also play a role in trafficking of proteins via its interaction with UNC119 and UNC119B cargo adapters: may help the release of UNC119 and UNC119B cargo or the recycling of UNC119 and UNC119B.  May play a role in ciliary membrane localization via its interaction with UNC119B and protein transport into photoreceptor cells.
What are the official names of this protein?
Macrophage immunometabolism regulator.
What is the protein family that this protein belongs to?
Belongs to the UNC119-binding protein family.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium. Note=Localizes to the transition zone and proximal cilium in addition to being found throughout the cytoplasm.
Protein: TLR9_HORSE
Sequence: MGPCHGALQPLSLLVQAAMLAVALAQGTLPPFLPCELQPHGLVNCNWLFLKSVPHFSAAAPRDNVTSLSLLSNRIHHLHDSDFAQLSNLQKLNLKWNCPPAGLSPMHFPCHMTIEPNTFLAVPTLEELNLSYNGITTVPALPSSLVSLILSRTNILQLDPTSLTGLHALRFLYMDGNCYYKNPCGRALEVAPGALLGLGNLTHLSLKYNNLTTVPRSLPPSLEYLLLSYNHIVTLAPEDLANLTALRVLDVGGNCRRCDHARNPCVECPHKFPQLHSDTFSHLSRLEGLVLKDSSLYQLNPRWFRGLGNLTVLDLSENFLYDCITKTKAFQGLAQLRRLNLSFNYHKKVSFAHLTLAPSFGSLLSLQELDMHGIFFRSLSQKTLQPLARLPMLQRLYLQMNFINQAQLGIFKDFPGLRYIDLSDNRISGAVEPVATTGEVDGGKKVWLTSRDLTPGPLDTPSSEDFMPSCKNLSFTLDLSRNNLVTVQPEMFAQLSRLQCLRLSHNSISQAVNGSQFVPLTSLQVLDLSHNKLDLYHGRSFTELPRLEALDLSYNSQPFSMRGVGHNLSFVAQLPTLRYLSLAHNGIHSRVSQQLCSTSLWALDFSGNSLSQMWAEGDLYLRFFQGLRSLIRLDLSQNRLHTLLPCTLGNLPKSLQLLRLRNNYLAFFNWSSLTLLPNLETLDLAGNQLKALSNGSLPSGTQLQRLDVSRNSIIFVVPGFFALATRLRELNLSANALRTVEPSWFGFLAGSLEVLDVSANPLHCACGAAFVDFLLQVQAAVPGLPSRVKCGSPGQLQGRSIFAQDLRLCLDESLSWDCFGLSLLVVALGLAMPMLHHLCGWDLWYCFHLGLAWLPRRGWQRGADALSYDAFVVFDKAQSAVADWVYNELRVRLEERRGRRALRLCLEERDWLPGKTLFENLWASVYSSRKMLFVLAHTDQVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDARRSRYVRLRQRLCRQSVLFWPHQPSGQRSFWAQLGMALTRDNRHFYNQNFCRGPTMAE
What is the function of this protein?
Key component of innate and adaptive immunity.  TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms.  TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides.  Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.  Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity).
What are the official names of this protein?
Toll-like receptor 9.
What is the protein family that this protein belongs to?
Belongs to the Toll-like receptor family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome. Lysosome. Cytoplasmic vesicle. Cytoplasmic vesicle, phagosome. Cell membrane. Cytoplasm. Nucleus. Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist. Exit from the ER requires UNC93B1. Endolysosomal localization is required for proteolytic cleavage and subsequent activation. Intracellular localization of the active receptor may prevent from responding to self nucleic acid.
Protein: MNGB_HALH5
Sequence: MKKTAHIISHSHWDREWYMPFEGHRYYLIQLMDDLLELFATDPNFRSFHMDGQTIMLEDYLNIRPEKEAEVRKYIQDGRLVIGPWYILQDAFLTSAEANVRNLLYGIKDTETFGQKREQIGYFPDTFGIYGQAPQLLAQAGIRAAVFGRGVTPTGFNNQVQHDDYSSPFSELIWEAPDGSQVIGILLANWYSNGNEIPTDEDEAQTFWVKKLRDAERFASTSQLLFMNGCDHQPVQKDVTQAIKVAETLFPDVAFKHSNFHDYLTQIKEELPKELQKITGELRNQKTDGWSTLVNTASARIYLKQANDRCQTLLTNVLEPMCLLVENKSLHRDFSEYYWKLLMENHPHDSICGCSIDAVHREMKTRFEKVEAGATTFIAEQGKEIAAQINTLHDSEEAIPLVVLKTNGTSGKRVVRHKVAMKKIYFDEMDFRHIPDRLKEIVMPTYRLEFPNKGSVPIEVQDAGVRFGYDLPRDGFRRPYYARELEVTFSYDSDLYLGYECGFLVPVEEKQTEARKELIGDPSMNTLENEAMKVMIHRNGSYSILDKTTGFEYRHLGIYEDVGDIGNEYMFKASSDGVRYTTEACEASIRIIENNSLCATVEICQTLSVPAAADERLKEEQERLVWHPDRKAGRSKERTDITLRTELTLEQGAKGLKVNVNIDNTAKDHRMRALFPVERARGNHYADSIYEIVERPNTPDPKWQNPAFDHHMQRLVSLDNGEYGLTIATKGLHEYEIVSDSIAVTLLRSVGELGDWGLFETPEAQCFGQNEAQFVLLPHKGDVLSANVYVAAYDDPVEPTVIQTEQSMGPLPHATNLFQWSGEGLVLTACKPTMDGRGMILRWFNPKREGEALIVQSTHFLQIYRSTILEEQIEKLGTENVQIEVRPQEIVTLRFE
What is the function of this protein?
May hydrolyze 6-phospho-mannosyl-D-glycerate to mannose-6-phosphate and glycerate.
What are the official names of this protein?
Putative mannosylglycerate hydrolase, 2-O-(6-phospho-mannosyl)-D-glycerate hydrolase, Alpha-mannosidase mngB.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 38 family.
Protein: MURC_RHOP2
Sequence: MRLPREIGPIHFVGIGGIGMSGIAEVLCNLGYTVQGSDASESANVSRLREKGIQIHVGHKADNVAGADVLVVSTAIKRDNPELLAARAQRIPVVRRAEMLAELMRLKSCVAIAGTHGKTTTTSMVAALLDAGDFDPTVINGGIINAYGTNARLGAGDWMVVEADESDGTFLKLPADVAIVTNVDPEHLDHFKTFDAVQDAFRNFVENVPFYGFAVMCIDHPVVQALVGKIEDRRIITYGENPQADARLLELKPSGSGSTFKVAFRDRKAGTAHEIAELMLPMPGRHNALNATAAIAVAHELGLSDDTIRKALAAFGGVRRRFTKTGDWNGVTIIDDYGHHPVEIAAVLKAARQSTDGRVIAVVQPHRFTRLQSLFEEFCTCFNDADSVIVADVYPAGEAPIQGIDRDHFVLGLRAHGHRNVIPLQDSASLAGVVAGVAKSGDYVVCLGAGNITQWAYALPGELKALGG
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VIPR1_MOUSE
Sequence: MRPPSLPPARWLCVLAGALACALGPAGSRAASPHQECEYLQMIEKQRQQCLEEAQLENETTGCSKMWDNLTCWPTTPWGQVVVLDCPLIFQLFSPIHGYNISRNCTEEGWSQLEPGPYHIACGLNDRASSMDEQQQTEFYDAVKTGYTIGYSLSLASLLVAMAILSLFRKLHCTRNYIHMHLFMSFILRATAVFIKDMALFNNGETDHCSEASVSCKAAVVFFQYCVMANFFWLLVEGLYLHTLLAVSFFSERKYFWGYILIGWGVPSVFIMIWTIVRIHFEDFGCWDTIINSSLWWIIKGPILISILVNFILFICIIRILVQKLRPPDIGKNDSSPYSRLAKSTLLLIPLFGVHYVMFAFFPDNFKAQVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWSSKSQHPWGGSNGVSCSTQVSMLTRVSPSARRSSSFQAEVSLV
What is the function of this protein?
This is a receptor for VIP.  The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
What are the official names of this protein?
Vasoactive intestinal polypeptide receptor 1, VIP-R-1, Pituitary adenylate cyclase-activating polypeptide type II receptor, PACAP type II receptor, PACAP-R-2, PACAP-R2, VPAC1.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 2 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y367_BORBU
Sequence: MADLEKINKIKVAEHIVECFGGIKNIKNIDKDLTRIKILVDSNSLVKRDDLTKNDNIIGTIKSNELTEVVINFEIIEDVYNKILYMMNEQKQ
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
What are the official names of this protein?
Putative phosphotransferase enzyme IIB component BB_0367, Putative PTS system EIIB component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y4JL_SINFN
Sequence: MQGQDLAMLPEIRLMGDVDVAALSPLFRGMVMTVSYAETQGGIGLTASGAMNRKFVHWAAVHFDWPGHTSDDLYSVSKVLNEADMPPLLVVRDMLKHLRLLRRRKDVLVPTQRGRDFLVRPQAFFDLIATDYLYAYIHYGQTREAVRNRMRWWHVFLNLINMKAETGCSLDDLANELYPSESYPEPAEMTVETWAERSALRYDSFARCAGWDCCTKSARG
What are the official names of this protein?
Uncharacterized protein y4jL.
Protein: PTNC_SHIFL
Sequence: MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLGDMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPLAAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVALSVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAAFTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II ManXYZ PTS system is involved in mannose transport.
What are the official names of this protein?
PTS system mannose-specific EIIC component, EII-P-Man, EIIC-Man, Mannose permease IIC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ARNT2_PSEF5
Sequence: MTSRIQMHRTSPPPAYGTSAPPSGFTLGASTTSTLQRWALPLLLVAFGLFYLLPLTSHGLWIPDETRYAQISQEMLLSGDWVAPHFMGIRYFEKPIAGYWLIAIGQAVFGDNLFGVRIASALSTGLSVLLAYLITRRMWNDPRKSFAAALLYMSFGLIAGQAGYSNLDPQFTLWVNLSLVALWFALDGRSTRERLLAWAGLGVACGMGFMTKGFLAWLLPVLIALPYMIWQRRLGELVRYGLVAVLVAIGISLPWVLSIHAHEPDFWRFFFWHEHIRRFAADNAQHTRPWWFYLPLLVASSLPWAALLPGTFMQAWKDKRQAPTGFLLLWFLLPLAFFSLSRGKLPTYIMPCLLPLAVLMGSALIDRINAIQGRSIRINSLLNLLIGVAAMVALLYIQLTRPVYGHNEMLGLSLVFIMLMGWIIANLLPAARPLQYWPAPALGIWLLVALLPAGMPGFIVHNQMPDQFIKEHIEELRQTKTLLSNDLGAASALAWRLQRPEVTLYNTEGELKYGLAYADSAQRKVSMAEVGQWVSEARKQGSVGVVMRVKDVVESEEVALLPPGGKRYEEGNMLVLILPQSQP
What is the function of this protein?
Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A.  The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
What are the official names of this protein?
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2, 4-amino-4-deoxy-L-arabinose lipid A transferase 2, Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase, Undecaprenyl phosphate-alpha-L-Ara4N transferase 2.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 83 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: ENO_DESAH
Sequence: MTEIIDVKAREILDSRGNPTVEVDVVLACGVQGRAAVPSGASTGTREALEMRDQDASRFLGKGVLKAVANVNEVIAPEIIGFDTMDQAGLDRTMIDMDGTENKSRLGANAILGVSMAAARAAAKAAEIPLYRHIGGINARILPVPMMNIINGGAHAPNNLDIQEFMILPFGAPSLCEAVRMGAETFHTLKKILKKEGLSTAVGDEGGFAPNLKSNEEAIEFIIRAIEEAGYRPGKDIGIALDAAASEFYKNGKYVFESEGQVLTSEELVDYYESLVTRYALYSIEDGLAEQDWTGWQMMTKRLGDSLQIVGDDVFVTNPDIFRKGISEGIGNSILIKLNQIGTVTETLDTIQMAKESGYTTVISHRSGETEDTFIADLAVAVNAGQIKTGSLSRSDRVAKYNQLIRIEEALGMGGIFPEDLFV
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: MNMG_BORA1
Sequence: MNYPHEFDVIVVGGGHAGTEAALAAARSGAKTLLLTHNIETLGQMSCNPSIGGIGKGHLVKEVDALGGAMAIATDEAGIQFRILNSSKGPAVRATRAQADRVLYRKAIRHRLENQENLWLFQQSVEDLIVEGDKVVGAVTQIGLKFRGRAVVLTAGTFLNGLIHVGLQHYSGGRAGDPPANSLGQRLKELKLPQGRLKTGTPPRIDGRTINYSVLEEQPGDLDPIPVFSFMGSAALHPRQLPCWITHTNERTHDIIRGGLDRSPMYSGVIEGIGPRYCPSIEDKIHRFADKPSHQIFLEPEGLDTHEVYPNGVSTSLPFDVQYELIHSLPGLEHAHILRPGYAIEYDYFDPRGLKSSLETKAISGLFFAGQINGTTGYEEAAAQGLLAGINAARYASDREAWVPRRDEAYLGVLVDDLVTRGVTEPYRMFTSRAEYRLSLREDNADLRLTEIGRELGLVDDIRWDVFNRKRDAIQAEVQRLQSTWVNPRLLPEEPAQALLGKAIEREYALADLLKRPNISYEALMQARNGAGELLAGPGLLGDDVLAEQVEIQIKYAGYIERQRDEVQKHVVHEQQAIPADIDYDAVSSLSFEVRQKLKTHRPETVGQAARISGVTPAAVSLLLIHLKRLHYGKRAI
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AROQ_FRATW
Sequence: MDVLVINGPNLNLLGTRQPQFYGHKTLADINNDLLKIAKENNINIDFYQSNHEGQIIDKIQQTAAKIIIINPAAFTHTSVAIRDAFLAINKPFIEIHLSNIYNREEFRTKSFLSDIAYGCIFGFGPNGYTLALIEAINYINMKGE
What is the function of this protein?
Catalyzes a trans-dehydration via an enolate intermediate.
What are the official names of this protein?
3-dehydroquinate dehydratase, 3-dehydroquinase, Type II DHQase.
What is the protein family that this protein belongs to?
Belongs to the type-II 3-dehydroquinase family.
Protein: RL9_STRZT
Sequence: MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAVGELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAEELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: Y1522_AERHH
Sequence: MAGHSKWANIKHRKAAQDAKRGKIFTKLIREITTSARLGDADPANNPRLRAAVAAALTGNMTRDTINRAIQRGAGGGDGEQLETIVYEGYGPAGSAVMVECLTDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGLLTFVGVDEDALMDAALEAGADDVVTEEDGSIEVYTTPNDFGTVLDGLEAAGFKPQSAEVTMIPSTEAELDAETAPKLMRLIDMLEDLDDVQEVYHNGSISDEVAATL
What are the official names of this protein?
Probable transcriptional regulatory protein AHA_1522.
What is the protein family that this protein belongs to?
Belongs to the TACO1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KCY_LENED
Sequence: MPTIIDKLSDALHLHSHQSTFDSKVTVIFVLGGPGAGKGTQCARLVEDFSFSHLSAGDLLRAEQHREGSEYGQLIQTCIKEGSIVPMEVTVKLLENAMTATLAERRSGEGWTDGQGRFLIDGFPRKMDQAEKFEHDVGKATAVLFFSTTQEVMLDRLLERGKTSGREDDNVESIKKRFNTYKEQTMPVIEHYEKLGKVIEIDSSVSIEEVHQKTRSAVAKLLSGSTA
What is the function of this protein?
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP.  Plays an important role in de novo pyrimidine nucleotide biosynthesis.  Has preference for UMP and CMP as phosphate acceptors, but can also use AMP and dCMP to a lesser extent.  May play a role during the formation of basidiospores in the gill tissue.
What are the official names of this protein?
UMP-CMP kinase, Deoxycytidylate kinase, CK, dCMP kinase, Uridine monophosphate/cytidine monophosphate kinase, UMP/CMP kinase, UMP/CMPK.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic.
Protein: SPEE_YERPG
Sequence: MSQKELWYETLHANFGQYFSVENVLFREKTEHQDLVIFENPELGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGQAKKVLIIGGGDGAMLREVSRHKNIEQITMVEIDAGVVEFCRQYLPNHSAGAYDDPRFKLVIDDGVNFVNQTTEKFDVIISDCTDPIGPGESLFTSVFYEGCARSLNEGGIFVAQNGVCFLQQDEAVNSHNKLSHYFSDVSFYQAAIPTYYGGIMTFAWATQNPALRQLDLATLQNRFAQAGLACRYYNPAIHVGSFALPQYLLDALTTIPKVIGVDSSE
What is the function of this protein?
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
What are the official names of this protein?
Polyamine aminopropyltransferase, Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UD14_RABIT
Sequence: MVLGVWITLWRLVRLLLLLCVLPWAEGGKVLVVPMDGSPWLSLREVVRDVHARGHQVLVLGPEVTMHIKGEDFFTLQTYATPYSKEEFDQLMQRNYQMIFKPQHSLKTLLETMENLKKFSMLCSRSCWELLHNKPLIKHLNESSFDVVLTDPLDLCGALLAKYLSVPSVFLLRFILCDLDFEGTQCPNPSSYIPRMLTMNSDHMSFLQRVKNMLYPLMMKYTCHISYDPYASLASELFQREVSLVDILSHASVWLFREDFVLDYPRPIMPNMVFIGGINCANRKPLSQEFEAYVNASGEHGIVVFSLGSMVSEIPEKKAMEIADALGKIPQTVLWRYTGSRPSNLAKNTYLVKWLPQNVLLGHPKTRAFITHSGSHGIYEGICNGVPMVMLPLFGDQMDNAKRIETRGAGVTLNVLEMTSDDLANALKTVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAAPRPAAHDLTWYQYHSLDVIGFLLAIVLTVAFVTFKCCAFAWGKCFGKKGRVKKAHKSKVH
What is the function of this protein?
UDP-glucuronosyltransferase (UGT) that catalyzes phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase the metabolite's water solubility, thereby facilitating excretion into either the urine or bile.  Essential for the elimination and detoxification of drugs, xenobiotics and endogenous compounds.  Involved in the glucuronidation of calcidiol, which is the major circulating form of vitamin D3 essential for the regulation of calcium and phosphate homeostasis.  Also glucuronidates the biologically active form of vitamin D3, calcitriol, probably leading to its biliary transport and intestinal reabsorption.
What are the official names of this protein?
UDP-glucuronosyltransferase 1A4, UGT1A4, UDP-glucuronosyltransferase 1-4, UDPGT 1-4, UGT1*4, UGT1-04, UGT1.4.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: LPXD_WIGBR
Sequence: MLEIKLSDVSKIISAKLYGDKNFIIKGISSIEDSKPGYISFIYKNKFRKYLPSCKASAIILAKDNLPFCKQFALVVKDPYIAYVKLVKFMYVKKIPKYRIRSTAIVSKKAILGKNIYIGHNTVIESKVKLENNIIIGSGCFIGENTIIGSNTHLWDNTTIHHGTIIGNNCSIQSGSVIGSDGFGYANKNGSWIKIPHLGKVVIGNNVEIGSSTTIDRGSIDNTVIGNGVIIDNQCQIAHNVIIGENTAIAGGVVMAGSLIIGSNCIIGGASVINGHIIICDRVKITGMSMVMRSIKTPGIYSSGVPAQLNKKWKKNTALIMNINKIKKQIKEILKKYKKK
What is the function of this protein?
Catalyzes the N-acylation of UDP-3-O-(hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor.  Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase, UDP-3-O-(3-OHC14)-GlcN N-acyltransferase, UDP-3-O-(3-hydroxytetradecanoyl)glucosamine N-acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the transferase hexapeptide repeat family. LpxD subfamily.