PharMolix/UniProtQA huggingface dataset:
Protein: MIRO_DROME
Sequence: MGQYTASQRKNVRILLVGDAGVGKTSLILSLVSEEYPEEVPPRAEEITIPANVTPEQVPTSIVDFSAVEQSEDALAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEAEAEGDTQREPIRKPIVLVGNKIDLIEYSTMDSVLAIMEDYPEIESCVECSAKSLHNISEMFYYAQKAVLHPTSPLYMMEEQELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQKNVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRPPLKIPPGSSTELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFSTCPAAPWSYSTDIRKSCPINETTGWVTLHGWLCRWTLMTLIDVVKTMEYLAYLGFNVHENDSQLAAIHVTRERRIDLAKRQSSRSVYKCHVIGPKGSGKTGMCRGFLVEDMHKLIGKEFKTNVVNCINSVQVYGQEKHLILRDIDVRHALDPLQPQEVNCDVACLVYDSSNPRSFEYVARIYIKYYAESKIPVMIVGTKCDMDERRQDYLMQPSEFCDKYKLLPPHLFSLKTNKKELYTKLATMAAFPHLRQFGLMTEDPKLWLKAGLGVAAATMLGFIVLKTISAAGAHTR
What is the function of this protein?
Mitochondrial GTPase involved in mitochondrial trafficking (PubMed:16055062, PubMed:16717129, PubMed:22396657).  Forms an essential protein complex with Milt that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria (PubMed:16717129).  Required for axonal transport to synapses within nerve terminals (PubMed:16055062, PubMed:22396657).  Required presynaptically but not postsynaptically at neuromuscular junctions (NMJs) (PubMed:16055062).  Also involved in the regulation of mitochondrial dynamics by promoting drp1-mediated mitochondrial fission during high calcium conditions, and negatively regulating fission during normal conditions (PubMed:27716788).
What are the official names of this protein?
Mitochondrial Rho GTPase, Miro, dMiro.
What is the protein family that this protein belongs to?
Belongs to the mitochondrial Rho GTPase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein.
Protein: HAS1_YEAST
Sequence: MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKMGFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVITPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQNTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLARISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDKRFLLLFSFLKRNQKKKIIVFLSSCNSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVDWIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPENKIANVQSQLEKLIKSNYYLHQTAKDGYRSYLQAYASHSLKTVYQIDKLDLAKVAKSYGFPVPPKVNITIGASGKTPNTKRRKTHK
What is the function of this protein?
ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis.  Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
What are the official names of this protein?
ATP-dependent RNA helicase HAS1, Helicase associated with SET1 protein 1.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: H10_XENTR
Sequence: MTENSAAAPAGKPKRSKASKKATDHPKYSDMILAAVQAEKSRSGSSRQSIQKYIKNHYKVGENADSQIKLSIKRLVTSGTLKQTKGVGASGSFRLAKADEGKKPAKKPKKEIKKAASPKKAAKPKKAAKSPAKAKKPKVAEKKVKKPAKKKPAPSPKKAKKTKTVKAKPVRASRVKKAKPSKPKAKASPKKSGRKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.  The histones H1. 0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division (By similarity).
What are the official names of this protein?
Histone H1.0, Histone H1(0), Histone H5.
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: ACP_MARMM
Sequence: MSDVLERVSKIVIEHLDVEAEKVTDKASFIDDLGADSLDNVELVMAFEEEFDIEIPDDAAEHIQTVGDAVKFISEKVG
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPRB_MYCTA
Sequence: MWWFRRRDRAPLRATSSLSLRWRVMLLAMSMVAMVVVLMSFAVYAVISAALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYSDVNAMLVNPGQSIYTAQQPGQTLPVGAAEKAVIRGELFMSRRTTADQRVLAIRLTNGSSLLISKSLKPTEAVMNKLRWVLLIVGGIGVAVAAVAGGMVTRAGLRPVGRLTEAAERVARTDDLRPIPVFGSDELARLTEAFNLMLRALAESRERQARLVTDAGHELRTPLTSLRTNVELLMASMAPGAPRLPKQEMVDLRADVLAQIEELSTLVGDLVDLSRGDAGEVVHEPVDMADVVDRSLERVRRRRNDILFDVEVIGWQVYGDTAGLSRMALNLMDNAAKWSPPGGHVGVRLSQLDASHAELVVSDRGPGIPVQERRLVFERFYRSASARALPGSGLGLAIVKQVVLNHGGLLRIEDTDPGGQPPGTSIYVLLPGRRMPIPQLPGATAGARSTDIENSRGSANVISVESQSTRAT
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  In response to environmental signals MprB acts as both a membrane-associated protein kinase that undergoes autophosphorylation and subsequently transfers the phosphate to MprA, and a protein phosphatase that dephosphorylates phospho-MprA (By similarity).
What are the official names of this protein?
Signal transduction histidine-protein kinase/phosphatase MprB, Mycobacterial persistence regulator B.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EFTS_BRASO
Sequence: MANITAAMVKDLRESTGAGMMDCKAALTETGGDMQAAQDWLRKKGLSKAAKKAGRVAAEGLIGALTSGKKGVVVEVNSETDFVARNEHFQGLVKMIAQVALDVGADVEKIKAAKVGSITVEAAIADSIATIGENQSLRRAAALEVSEGVVASYVHGAVIEGAGKLGVIVALESPGKTDELAALGRQLAMHVAAANPQAIDAAGLDPEVVKREKDVLSDKYRQQGKPENVIEKIVESGLKTYYKEVTLLEQAFIHDSGKSVAQALKEAEGKVGGPIKVAGFVRYALGEGIEKEETDFAAEVAAASGKK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMB_SALCH
Sequence: MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQWQRIIDANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAVFLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPAQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSETGTPDQPGQQNLPGGEEGDGFFYAKLIKK
What is the function of this protein?
Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase B, 16S rRNA m5C967 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmB.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DUS3_CANAL
Sequence: MITPEKRTLDEPEVGSESKKPNNSTHVKGVAAIKAEYLVPTSSLTVVEYDDDEAEGGDREGESKPRNKKKQKGQNHKRDLKQKKDIIKLCPSLIDPEDDRICQVGADKCRFHHDIASYLESKPQDIDGICPVFEALGYCPTGIKCRWLKSHYNPETSKLIKDGDKMETAKTTNYEVNHIDKDQKMEMQKKKYFFKISQPVIKYLDSRIQNEANLAKQKEERKDNEASYVEAPFTIAEKKKLYLRNAKIVSPLTTVGNLPYRRLMKTLGADVTYSEMALSVPLIQGHNPEWALPKAHVSEYPGFGVQIASSKHWAAAKAAEAIYRNTTHVSELNLNCGCPIDLLYKQGQGSALLDQPSKLLRILSGMNASSGDIPVTVKIRTGIKEGKNTAVNLVSRVLEEGNAAAITLHGRSRQQRYSKEADWNYIAEVGTVVKNWNEQQKEDKEGRDRDPVYFVGNGDVYSHEDWYEHVNTDGIDSVMVARGALIKPWIFEEVEAQQYLDKSSSERLDILGKFAKYAIEHWGSDEYGVGLSRRFMCEFLSFTHRYIPVGIMERLPPKLNERPPKWVGRNDLETLLASTDYKDWIKITEMFLGKATDDFQFTPKHKSNAYENK
What is the function of this protein?
Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.  Specifically modifies U47 in cytoplasmic tRNAs (By similarity).  Catalyzes the synthesis of dihydrouridine in some mRNAs, thereby affecting their translation (By similarity).
What are the official names of this protein?
tRNA-dihydrouridine(47) synthase [NAD(P)(+)], mRNA-dihydrouridine synthase DUS3, tRNA-dihydrouridine synthase 3.
What is the protein family that this protein belongs to?
Belongs to the Dus family. Dus3 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDE_CRODO
Sequence: GLKEPVQPQVSCRYRCNETFSRMASGCSCDDKCTERQACCSDYEDTCVLPTQSWSCSKLRCGEKRIANVLCSCSEDCLEKKDCCTDYKTICKGETSWLKDKCASSGATQCPAGFEQSPLILFSMDGFRAGYLENWDSLMPNINKLKTCGTHAKYMRAVYPTKTFVNHYTIATGLYPESHGIIDNNIYDVNLNLNFSLSSSTARNPAWWGGQPIWHTATYQGLKAATYFWPGSEVKINGSYPTIFKNYDKSIPFEARVTEVLKWLDLPKAKRPDFFTLYIEEPDTTGHKYGPVSGEIIKALQMADRTLGMLMEGLKQRNLHNCVNLILLADHGMEEISCDRLEYMANYFDNVDFFMYEGPAPRIRSKNVPKDFYTFDSEGIVKNLTCRKPKQYFKAYLSKDLPKRLHYANNIRIDKVNLMVDQQWMAVRDKKFTRCKGGTHGYDNEFKSMQAIFLAHGPGFNEKNEVTSFENIEVYNLMCDLLKLKPAPNDGTHGSLNHLLKNPFYTPSPAKEQSSPLSCPFGPVPSPDVSGCKCSSITELEKVNQRLNLNNQAKTESEAHNLPYGRPQVLQNHSKYCLLHQAKYISAYSQDILMPLWSSYTIYRSTSTSVPPSASDCLRLDVRIPAAQSQTCSNYQPDLTITPGFLYPPNFNSSNFEQYDALITSNIVPMFKGFTRLWNYFHTTLIPKYARERDGLNVISGPIFDYNYDGHFDSYDTIKQHVSNTKIPIPTHYFVVLTSCENQINTPLNCLGPLKVLSFILPHRPDNSESCADTSPENLWVEERIQIHTARVRDVELLTGLNFYSGLKQPLPETLQLKTFLPIFVNPVN
What is the function of this protein?
Hydrolyzes ADP with high activity.  Shows weak or no activity on 5'-AMP, 5'-GMP, 3'-AMP, ATP, cAMP, and cGMP (By similarity).  Is devoid of monophosphatase and proteinase activities (By similarity).  Inhibits ADP-induced platelet aggregation and is cytotoxic to human keratinocytes (PubMed:33636276).  Kinetic parameters indicated a higher affinity for the substrate bis(p-nitrophenyl) phosphate compared to others snake venom PDEs (PubMed:33636276).  Is recognized by the crotalid antivenom produced by the Instituto Butantan (PubMed:33636276).
What are the official names of this protein?
Venom phosphodiesterase CdcPDE, PDE.
What is the protein family that this protein belongs to?
Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
What are the subcellular locations of this protein?
Secreted.
Protein: GBG10_HUMAN
Sequence: MSSGASASALQRLVEQLKLEAGVERIKVSQAAAELQQYCMQNACKDALLVGVPAGSNPFREPRSCALL
What is the function of this protein?
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems.  The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.  Interacts with beta-1 and beta-2, but not with beta-3.
What are the official names of this protein?
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10.
What is the protein family that this protein belongs to?
Belongs to the G protein gamma family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: NGRN_HUMAN
Sequence: MAVTLSLLLGGRVCAAVTRCGFATRGVAGPGPIGREPDPDSDWEPEERELQEVESTLKRQKQAIRFQKIRRQMEAPGAPPRTLTWEAMEQIRYLHEEFPESWSVPRLAEGFDVSTDVIRRVLKSKFLPTLEQKLKQDQKVLKKAGLAHSLQHLRGSGNTSKLLPAGHSVSGSLLMPGHEASSKDPNHSTALKVIESDTHRTNTPRRRKGRNKEIQDLEESFVPVAAPLGHPRELQKYSSDSESPRGTGSGALPSGQKLEELKAEEPDNFSSKVVQRGREFFDSNGNFLYRI
What is the function of this protein?
Plays an essential role in mitochondrial ribosome biogenesis.  As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
What are the official names of this protein?
Neugrin, Mesenchymal stem cell protein DSC92, Neurite outgrowth-associated protein, Spinal cord-derived protein FI58G.
What is the protein family that this protein belongs to?
Belongs to the neugrin family.
Protein: TCL1A_HUMAN
Sequence: MAECPTLGEAVTDHPDRLWAWEKFVYLDEKQHAWLPLTIEIKDRLQLRVLLRREDVVLGRPMTPTQIGPSLLPIMWQLYPDGRYRSSDSSFWRLVYHIKIDGVEDMLLELLPDD
What is the function of this protein?
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3.  Promotes nuclear translocation of AKT1.  Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
What are the official names of this protein?
T-cell leukemia/lymphoma protein 1A, Oncogene TCL-1, Oncogene TCL1, Protein p14 TCL1.
What is the protein family that this protein belongs to?
Belongs to the TCL1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Note=Microsomal fraction.
Protein: GATA_DICNV
Sequence: MSDLHHKTVAELATLLHNKTLSSVELTQHFLSRIQQYNPKLNAYICTTADRALADAKASDERRQKGAAHSPLDGIPMGHKDLFCTKGIATTAGSKMLERFIPSYTATVVARLEAAGSVLTGKLSMDEFAMGSSNERSYFGAVYNPWDEQRIPGGSSGGSAAAVAARLIPYATGSDTGGSVRQPAAYCGITGIKPTYGTCSRWGMIAYASSLDQAGVLAKTAQDCALILNEMAGHDPKDSTSNPKALTQFDHELNRDLDGITIGLPSNYLAGLDAKIAEKLQQTAALYEKLGATIKEITLSATDVAIASYYLISSAEASSNLERFDGVHYGYRCANPKDLSDLYERSRSEGFGAEVKRRIMIGTYALSAGYYDAYYEQARRGRRAILNSFLQAFKECDVILGPTTPTTAYPLGSKVDDPVAMFLGDLYTVSANLAGLPALSHPAGFIDGLPVGCQLIGAHFSEPQLLNLAHRFQQETDFHQQIPEHYR
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: RS18_METEP
Sequence: MAFGAGGGGGGRRPFFRRRKSCPFSGENAPKIDYKDVKLLSRYVSERGKIVPSRITAVSAKKQRELAQAIKRSRFLGLLPYVIK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: PSBF_PHYPA
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGAISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: TM45B_BOVIN
Sequence: MANFKGHALPGSFFLIVGLWWSLKYPLKYFYQKEKSNQLTHHYQRLEIIEAAIRTLFAVIGILVEQFVPDGPHLHLYHEDHWVKLMNWQHSTMYLFFAVSGIMDMLTYLITHVPLGLDRLVMALAAFNEGFLFYYHVRDRPPLDQHIHSLLLYTVFGGALSLAVEVVLRDNIVLELFRTSLLLLQGTWFWQIGFVLFPPFGGPEWDQNSHDNIMFVTMCFCWHYLAALCILAASYSLVYCFLTRVKRPEDREVIGIQKLRSDHTYRKALLSGSDEE
What is the function of this protein?
Plays a role in innate immunity.
What are the official names of this protein?
Transmembrane protein 45B.
What is the protein family that this protein belongs to?
Belongs to the TMEM45 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSAI_CHAGL
Sequence: MAASFLPSILVPLVGLVFPAIAIASLFIYIEQDEII
What is the function of this protein?
May help in the organization of the PsaL subunit.
What are the official names of this protein?
Photosystem I reaction center subunit VIII, PSI-I.
What is the protein family that this protein belongs to?
Belongs to the PsaI family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PGK_BACCQ
Sequence: MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGAKVILASHLGRPKGQVVEELRLTPVAARLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKNDAELAKEFAALADIFVNDAFGAAHRAHASTAGIADYLPAVSGLLMEKELDVLGKALSNPDRPFTAIIGGAKVKDKIGVIRHLLDKVDNLIIGGGLAYTFVKALGHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATTKIVGIDSIPSNWEGVDIGPKTREIYADVIKNSKLVVWNGPMGVFEMTPFSQGTKAVGQALADAEGTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLEFMEGKELPGVVCLNDK
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VP2_POVLY
Sequence: MGGVLSLLFNISEIAAELSLSTGFTVDAILTGEAFAAVSTEAAWLIEIEAVDLAGLSTLEALSLTGLTTEQFSLLSAIPTALNNAIGIGVFFQTVSGASAVVAAGVTTFGYSKEVPVVNMALVPWFPQVDYLFPGFTSFSYYLNAVLDWGESLFHAVGREVWRHLMRQATLQIGQATRAVAVRSTNELSHTLAQIAENARWALTSGPVHIYSSVQDYYRYLPARNPIQLRQEYRNRGEPPPSRADFEYQENREGQRARRELGYDEPRSGQYVEHYTAPGGAHQRVTQDWMLPLILGLYGDITPTWEVELNKLEKEEDGPSKKKARRSMQKNMPYSRSRPQAPSKRRSRGARSKNRA
What is the function of this protein?
Structural protein that resides within the core of the capsid surrounded by 72 VP1 pentamers.  Following virus endocytosis and trafficking to the endoplasmic reticulum, VP2 and VP3 form oligomers and integrate into the endoplasmic reticulum membrane.  Heterooligomer VP2-VP3 may create a viroporin for transporting the viral genome across the endoplasmic reticulum membrane to the cytoplasm.  Nuclear entry of the viral DNA involves the selective exposure and importin recognition of VP2 or VP3 nuclear localization signal (shared C-terminus).  Plays a role in virion assembly within the nucleus (By similarity).
What are the official names of this protein?
Minor capsid protein VP2, Minor structural protein VP2.
What is the protein family that this protein belongs to?
Belongs to the polyomaviruses capsid protein VP2 family.
What are the subcellular locations of this protein?
[Isoform VP2]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane. SUBCELLULAR LOCATION: [Isoform VP3]: Virion. Host nucleus. Host endoplasmic reticulum. Host endoplasmic reticulum membrane.
Protein: RLI1_ORYSI
Sequence: MLQDIMNTKKIKLHDCHFGSPLCDPSPAPHLLSSAAAAGLSFHPGLVSSAAQHQQHGAGGWLHEEYYAPRSSPPSSLLAQTCVGSNATAFYAAENLPQFDFPALGTAAAAAAKAPFRSSESELYRPVDPLLLRADHSVRTYYVRPQKRDSGERTPLPPPSQQQHQDRIHGLFAGAPTTRLLSGEPKIHLFPPQVAAKPILPAMDAPSLQNQMENQLTRNCIGAATPVTPTGNLAGSGAPSKTRIRWTQDLHERFVDCVNQLGGADKATPKGILKLMNSDGLTIYHIKSHLQKYRIAKYMPASSEGKQLEKRATGNDMQNLDPKTGMQITEALRVQLDVQRRLHEQLEIQRNLQLRIEEQGKRLQKMFEDQLKASRSVMEPQELDDVVAFAAGDGDDDAFDDVDVQLLAVAGSGYDDAGFQSKIS
What is the function of this protein?
Transcription factor binding to specific DNA sequences of target genes promoters, such as the motif R1BS 5'-NAKATNCN-3' and the motif P1BS 5'-GNATATNC-3' to trigger their expression (By similarity).  Nitrate-induced component involved in modulating phosphate (Pi) response and homeostasis together with PHR2; activates directly the expression of Pi starvation-induced (PSI) genes upon nitrate disponibility, thus triggering the nitrate-induced phosphate response (NIPR) promoting Pi uptake activity (By similarity).  Involved in the shoot architecture; regulates positively leaf inclination by affecting lamina joint cell elongation via the direct promotion of ILI4/BU1 and BC1 genes expression, especially in response to phosphate (Pi) availability (By similarity).  Regulates both brassinolide (BL) biosynthesis and signaling by directly activating BL-biosynthesis and signaling genes (By similarity).
What are the official names of this protein?
Myb family transcription factor RLI1, Protein HIGHLY INDUCED BY NITRATE GENE 1, Protein REGULATOR OF LEAF INCLINATION 1.
What is the protein family that this protein belongs to?
Belongs to the MYB-CC family.
Protein: MOAC_ECOL5
Sequence: MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEADD
What is the function of this protein?
Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
What are the official names of this protein?
Cyclic pyranopterin monophosphate synthase, Molybdenum cofactor biosynthesis protein C.
What is the protein family that this protein belongs to?
Belongs to the MoaC family.
Protein: DXS_DESHY
Sequence: MGILAKIEQPRDLKGLTYPELEQLAQEIRAEMIDVVSANGGHLAPNLGVVELTLALHRVFDSPKDKIIWDVGHQSYVHKLVTGRQKEFKSLRLYKGLSGFPKRCESPHDCFETGHSSTSISAAVGFAKARDLRKEKNQVVAVIGDGAMTGGMAFEALNHAGHTKTNMIVVLNDNEMAIAQNVGAMSSYLNRLRTDPRYDRSKDEIENLLKRIPGIGSKMAKAAEKAKDSLKYLLVPGLLFEEMGFTYLGPVNGHDQIALEQVFEQAKMVKEPVLVHVLTQKGRGYEPSEKNPALFHGVGPFNKVTGEVIKKPAPPTYTQVFGETLCELAEKDPRITAITAAMPSGTGLNLFAQKFPDRFFDVGIAEQHAVTFSAALAFGGMKPVVSIYSTFYQRAYDQVLHDVCLPHANVVMAIDRAGVVGDDGPTHHGVFDISFLRVIPNLVFMAPKDENELRHMLYTSLQLDGPVALRYPRSVGQGVELTEELRELPVGKAEILQEGKDITLIGVGPMVYTCLAAAVELRHRGVEATVINLRYINPLDRESILRYARMTKRIITVEDHMLAGGMGSAVMEVLGDEGLTDVVVERLGYDEYVDQGAISLLHQGYGLSVVGILKAAERLKVLQRIEGRSSV
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: ADDL_STRCO
Sequence: MERVRDVSELPKAHLHLHFTGSMRPTTLLELADKHGVRLPETLTEALGRGESPKLRATDERGWFRFQRLYDAARSCLQTPEDIQRLVREAAEEDLRDGSGWLEIQVDPTSYAPRLGGLIPALEIILDAVETTVRDTGIGMRVLVAANRMKHPLDARTLARLAVRYAERGVVGFGLSNDERRGMARDFDRAFAIARDGGLLSAPHGGELTGPASVRDCLDDLEADRIGHGVRAAEDPRLLKRLADRQVTCEVCPASNVALGVYEKPEDVPLRRLFEAGVPMALGADDPLLFGSRLAAQYEIAREHHGFTDAELAELARQSVRGSAAPEEVKGKLLAGVDDWLVA
What is the function of this protein?
Putative nucleoside deaminase.  May catalyze the hydrolytic deamination of adenosine or some similar substrate and play a role in purine metabolism (By similarity).
What are the official names of this protein?
Putative adenosine/adenine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Protein: TRM5_BOVIN
Sequence: MRSLLKQFAFSRRLLKVESCRITESASLILLPWASLIQKLNRVPVIFLLDQRKRFSTMPEIETNHRDSELFSPPSEVRGMTELDRTAFKKTVTIPVLKVRKEVVNKLMRSLKRAALQRPGIKRVIEDPEDGEGRLIMLDPYKMFTVDSFEKEELSILKQLNVNPQISKYNLDLTYENFKSEEILRAVLPEGQDVTSGFSRVGHIAHLNLRDHQLPYKHLIGQVMIDKNPGITSAVNKINNIDNTYRNFEMEVLSGEENMMTKVRENNYTYEFDFSKVYWNPRLSTEHSRITELLKPGDVLFDVFAGVGPFAIPAAKKKCTVFANDLNPESHKWLLHNCKLNKVDQKVKVFNLDGRDFLQGPVREELMQQLGPLSKERKHSVHIVMNLPAKAIEFLSAFKALLEGQPCGSELLPIVHCYSFSKDANPAKDVQQRAATVLGISLEAYSSVHLVRNVAPNKEMLCITFRIPAAILYKNQTVNRDNHEGPPLKRQRTDKDF
What is the function of this protein?
Involved in mitochondrial tRNA methylation (By similarity).  Specifically methylates the N1 position of guanosine-37 in various tRNAs.  Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside.  This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.
What are the official names of this protein?
tRNA (guanine(37)-N1)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase, tRNA methyltransferase 5 homolog.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cytoplasm. Note=Predominantly in the mitochondria and in the nucleus.
Protein: RL33_WOLPP
Sequence: MAKKNASLLVKLVSTATKTTKTGEEKLTGYFCVKKRNPKNLPKKLEFRKYDPVVRRHVLFKEEKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.