PharMolix/UniProtQA huggingface dataset:
Protein: SPT4A_MOUSE
Sequence: MALETVPKDLRHLRACLLCSLVKTIDQFEYDGCDNCDAYLQMKGNREMVYDCTSSSFDGIIAMMSPEDSWVSKWQRVSNFKPGVYAVSVTGRLPQGIVRELKSRGVAYKSRDTAIKT
What is the function of this protein?
Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates mRNA processing and transcription elongation by RNA polymerase II.  DSIF positively regulates mRNA capping by stimulating the mRNA guanylyltransferase activity of RNGTT/CAP1A.  DSIF also acts cooperatively with the negative elongation factor complex (NELF complex) to enhance transcriptional pausing at sites proximal to the promoter.  Transcriptional pausing may facilitate the assembly of an elongation competent RNA polymerase II complex.  DSIF and NELF promote pausing by inhibition of the transcription elongation factor TFIIS/S-II.  TFIIS/S-II binds to RNA polymerase II at transcription pause sites and stimulates the weak intrinsic nuclease activity of the enzyme.  Cleavage of blocked transcripts by RNA polymerase II promotes the resumption of transcription from the new 3' terminus and may allow repeated attempts at transcription through natural pause sites (By similarity).
What are the official names of this protein?
Transcription elongation factor SPT4-A, DRB sensitivity-inducing factor small subunit 1, DSIF small subunit 1, Transcription elongation factor SPT4 1.
What is the protein family that this protein belongs to?
Belongs to the SPT4 family.
Protein: RSMH_STRPF
Sequence: MTKEFHHVTVLLHETVDMLDIKPNGIYVDATLGGSGHSAYLLSKLSEQGHLYCFDQDQKAIDNAQVTLKSYIDKGQVTFIKDNFRHLKARLTALGVDEIDGILYDLGVSSPQLDERERGFSYKQDAPLDMRMDRQSLLTAYEVVNTYPFNDLVKIFFKYGEDKFSKQIARKIEQARAIKPIETTTELAELIKAAKPAKELKKKGHPAKQIFQAIRIEVNDELGAADESIQDAMELLALDGRISVITFHSLEDRLTKQLFKEASTVDVPKGLPLIPEDMKPTFELVSRKPILPSHSELTANKRAHSAKLRVAKKIRK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VPE_RICCO
Sequence: METHKSLLFFTNYVLFLVFTLSFLPIPGLLASRLNPFEPGILMPTEEAEPVQVDDDDQLGTRWAVLVAGSMGFGNYRHQADVCHAYQLLRKGGLKEENIIVFMYDDIAKNELNPRPGVIINHPQGEDVYAGVPKDYTGEHVTAKNLYAVLLGDKSAVQGGSGKVVDSKPNDRIFLYYSDHGGPGVLGMPNLPYLYAMDFIEVLKKKHAAGGYKKMVIYVEACESGSIFEGIMPKDVDIYVTTASNAQESSWGTYCPGMEPSPPPEFTTCLGDLYSVAWMEDSESHNLKKETVKQQYSSVKARTSNYNTYAAGSHVMQYGNQSIKADKLYLFQGFDPASVNFPPNNAHLNAPMEVVNQRDAELHFMWQLYKRSENGSEKKKEILQQIKDAIKHRSHLDSSMQLIGDLLFGPKKASAILKSVREPGSPLVDDWGCLKSMVRVFETCCGSLTQYGMKHMRTFANICNAGVSHTSMEEACNAACSGHDAGQWHPTNQGYSA
What is the function of this protein?
Asparagine-specific endopeptidase involved in the processing of vacuolar seed protein precursors into the mature forms.
What are the official names of this protein?
Vacuolar-processing enzyme, VPE.
What is the protein family that this protein belongs to?
Belongs to the peptidase C13 family.
Protein: HPRT_LEIDO
Sequence: MSNSAKSPSGPVGDEGRRNYPMSAHTLVTQEQVWAATAKCAKKIAEDYRSFKLTTDNPLYLLCVLKGSFIFTADLARFLADEGVPVKVEFICASSYGTGVETSGQVRMLLDVRDSVENRHILIVEDIVDSAITLQYLMRFMLAKKPASLKTVVLLDKPSGRKVEVLVDYPVITIPHAFVIGYGMDYAESYRELRDICVLKKEYYEKPESKV
What is the function of this protein?
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate.  Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine.  Plays a central role in the generation of purine nucleotides through the purine salvage pathway (By similarity).
What are the official names of this protein?
Hypoxanthine-guanine phosphoribosyltransferase, HGPRT, HGPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSPP_TRIST
Sequence: MVLIRVLANLLILQLSYAQKSPELVVGGDECNINEHRSLVAIFNSTGFFCSGTLINQEWVVTAAHCDSNNFKMKFGAHSQKVLNEDEQIRNPKEKFICPNKKNNEVLDKDIMLIKLDSSVSNSEHIAPLSLPSSPPSVGSVCRIMGWGSITPTKVTYPDVPYCANINLLDDAECKPGYPELLPEYRTLCAGIVQGGKDTCGGDSGGPLICNGQFHGIVSYGAHPCGQSLKPGIYTTVFDYNDWIKSIIAGNTAATCPP
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease PA, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS4_LIMF3
Sequence: MSRYTGPSWRLSRRLGVSLSGTGKELARRPYAPGDHGNDRRGKLSEYGTQLREKQKLRFMYGMTERQFSNLFVRAGKIKEGTHGTNFMVLLERRLDNMVYRLGLATTRRQARQLVNHGHITVDGKRVDIPSYEVKVGQVIAVREKSKNLDVIKGAVEAVVARPAYVEFDADKLEGKLTRLPQREDMNADIDEALIVEFYNK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: MURR_CITK8
Sequence: MLYLAKMRNAEGELTENEQKIASFLLAHVSELKTVSSRNLAKQLEVSQSSIVKFAQKLGAKGFTELRMALIEEYSVNREKKHDTALHLHSTITSEDSLEVIARKLNREKMFALEETCSLMDFDRLKQVINLISKARLIQITGVGGSALVGRDLSFKLMKIGYRVACEVDTHVQATIAQALQEGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLTDSPLRRLADYTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGMVQLNDVESLRMIERSSELINLLGRS
What is the function of this protein?
Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc).  Binds to two adjacent inverted repeats within the operator region.  MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator.
What are the official names of this protein?
HTH-type transcriptional regulator MurR, MurPQ operon repressor.
Protein: RTNLN_ARATH
Sequence: MAVFGYEMDEHRASSSRRRRSLYHNLGGGRFADIMFWKNKKESGTILGVFTLIWFLFEVVEYPFITFLCQILLLFIFIFLIWSYIGSSQLIQSKPPSINDLRISESNWRFLFNKINWFIIKLYDISSGKDFRLLFLAVVSLWILSVVGNYFSSLTLLYIVFVGLETIPMLYEQYEEELTYAASKSGRDMKKLLNKFNSKVINKIPKAQAKTRRTM
What are the official names of this protein?
Reticulon-like protein B14, AtRTNLB14.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: CYB_ANTSW
Sequence: MTNLRKTHPLMKIINHSFIDLPAPSNISAWWNFGSLLGVCLIIQILTGFFLAMHYTSDMLTAFSSVAHICQDVNYGWLVRNLHANGASMFFMCLFLHVGWGIYYGSYLYKETWNIGVILLLTEMATAFVGYVLPWGQMAFWGATVITNLLSAIPYIGTTLAEWIWSGFAVDKATLTQFFTLHFILSFIVMALAIVHLLFLHETGSNNPSGINPDSDKIPFHPYYTIKDTLGLLFLFLTLLLLALFSPDSLGDPDNFSPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLASILVLLIIPFLHTANQRSMMFRPISQTLFWILTANLITLTWIGGQPVEQPFIIIGQVASMSYFLLILVLMPLAGLFENYMLKPKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: DAO1_TOBAC
Sequence: MATTKQKVTAPSSSTAPCCPSTSILRREATAAVAGVGDGLQNWNNVPSVDDKQKKTASSALASLASTEPLSSNTSTKGIQIMTRAQTCHPLDPLSAAEISVAVATVRAAGETPEVRDGMRFIEVVLLEPDKSVVALADAYFFPPFQSSLMPRTKGGSLIPTKLPPRRARLIVYNKKTNETSIWIVELNEVHAAARGGHHRGKVISSNVVPDVQPPIDAQEYAECEAVVKSYPPFRDAMRRRGIDDLDLVMVDPWCVGYHSEADAPSRRLAKPLVFCRTESDCPMENGYARPVEGIYVLVDVQNMQIIEFEDRKLVPLPPADPLRNYTAGETRGGVDRSDVKPLHIIQPEGPSFRISGNYIEWQKWNFRIGFTPREGLVIHSVAYLDGSRGRRPIAHRLSFVEMVVPYGDPNDPHYRKNAFDAGEDGLGKNAHSLKRGCDCLGYIKYFDAHFTNFTGGVETTENCVCLHEEDHGMLWKHQDWRTGLAEVRRSRRLTVSFVCTVANYEYAFYWHFYQDGKIEAEVKLTGILSLGALQPGEYRKYGTTILPGLYAPVHQHFFVARMNMAVDCKPGEAHNQVVEVNVKVEEPGKENVHNNAFYAEETLLRSELQAMRDCDPFSARHWIVRNTRTVNRTGQLTGYKLVPGPNCLPLAGPEAKFLRRAAFLKHNLWVTQYAPGEEFPGGEFPNQNPRVGEGLASWVKQDRPLEESDIVLWYIFGITHVPRLEDWPVMPVEHIGFVLQPHGFFNCSPAVDVPPPSACDSESRDSDVTETSVAKSTATSLLAKL
What is the function of this protein?
Involved in putrescine catabolism in peroxisomes (PubMed:24287136).  May also be involved in the biosynthesis of pyridine alkaloid natural products, leading mainly to the production of anabasine, anatabine, nicotine and nornicotine, effective deterrents against herbivores with antiparasitic and pesticide properties (neurotoxins); nornicotine serves as the precursor in the synthesis of the carcinogen compound N'-nitrosonornicotine (NNN) (PubMed:16656744).  Oxidizes preferentially non-N-methylated amines (PubMed:24287136).
What are the official names of this protein?
Diamine oxidase [copper-containing] 1, peroxisomal, NtDAO1, Copper methylamine oxidase, N-methylputrescine oxidase 2, peroxisomal, NtMPO2.
What is the protein family that this protein belongs to?
Belongs to the copper/topaquinone oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: CYC6L_NOSS1
Sequence: MQKFLKLVLVTFLFLISTLTPPANAENTINGEQIFSVHCAGCHINGSNIIRRGKNLQKKTLKKYGMDSLEAIEAIVTNGKNNMSAYKDRLSEQEIQDVAAYVLEQAEKGWR
What are the official names of this protein?
Cytochrome c6-like.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family. PetJ subfamily.
What are the subcellular locations of this protein?
Cellular thylakoid lumen.
Protein: MVP_CAMVW
Sequence: MDLYPEENTQSEQSHNSENNMQIFKSENSDGFSSDLMISNDQLKNISKTQLTLEKEKIFKMPNVLSQVMKKAFSRKNEILYCVSTKELSVDIHDATGKVYLPLITKEEINKRLSSLKPEVRRTMSMVHLGAVKILLKAQFRNGIDTPIKIALIDDRINSRKDCLLGAAKGNLAYGKFMFTVYPKFGISLNTQRLNQTLSLIHDFENKNLMNKGDKVMTITYIVGYALTNSHHSIDYQSNATIELEDVFQEIGNVQQSEFCTIQNDECNWAIDIAQNKALLGAKTKSQIGNSLQIGNSASSSNTENELARVSQNIDLLKNKLKEICGE
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier.  Acts by forming tubules structures that increase the size exclusion limit (SEL) of plasmodesmata, thereby allowing viral ribonucleocapsids to spread directly to neighboring cells (By similarity).
What are the official names of this protein?
Movement protein, Mov, Cell-to-cell transport protein.
What is the protein family that this protein belongs to?
Belongs to the caulimoviridae movement protein family.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Note=Assembles in tubules that are embedded within modified plasmodesmata.
Protein: CSTF1_MOUSE
Sequence: MYRTKVGLKDRQQLYKLIISQLLYDGYISIANGLINEIKPQSVCAPSEQLLHLIKLGMENDDTAVQYAIGRSDTVAPGTGIDLEFDADVQTMSPEASEYETCYVTSHKGPCRVATYSRDGQLIATGSADASIKILDTERMLAKSAMPIEVMMNETAQQNMENHPVIRTLYDHVDEVTCLAFHPTEQILASGSRDYTLKLFDYSKPSAKRAFKYIQEAEMLRSISFHPSGDFILVGTQHPTLRLYDINTFQCFVSCNPQDQHTDAICSVNYNPSANMYVTGSKDGCIKLWDGVSNRCITTFEKAHDGAEVCSAIFSKNSKYILSSGKDSVAKLWEISTGRTLVRYTGAGLSGRQVHRTQAVFNHTEDYILLPDERTISLCCWDSRTAERRNLLSLGHNNIVRCIVHSPTNPGFMTCSDDFRARFWYRRSTTD
What is the function of this protein?
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs (By similarity).  May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (By similarity).
What are the official names of this protein?
Cleavage stimulation factor subunit 1, CF-1 50 kDa subunit, Cleavage stimulation factor 50 kDa subunit, CSTF 50 kDa subunit, CstF-50.
What are the subcellular locations of this protein?
Nucleus.
Protein: PIGP_ARATH
Sequence: MLSLNQEVHGPKTSEVYGFVGSISIVVATVIFLIWGYVPDKFLESIGIYYYPSKYWAMAMPMYSMVTLLVALVFYIGLNFMSTSKPTSLNTLFDDYSREDVNFLPLMKNGEDRPIDPISDIDITRINDLMFDSHLAK
What is the function of this protein?
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
What are the official names of this protein?
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P.
What is the protein family that this protein belongs to?
Belongs to the PIGP family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PDRP_GEOSM
Sequence: MYHVYLLSDATGETVERVARAALTQFRDVDIRLRRMGQIRNREDILRALDEVDRAPGIIFYTLVNTELAQFVRNEVEARQLEAVDLITPLLYKLAEFLEMRPQKLPGLQYEMNSEYYRRMEAVDFTVKQDDGQEPRNLHKADIVLIGVSRSSKTPLSMYLAHKGYKVANVPIIQGIDPPGELEEVEPERVVGLIIDTQRLVDIRSARLRNLRQSPRGSYADYRQVEEELSYCRRFYRAHPAWLVIDVTNKSVEESAAEILSRLHGDIRHD
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: ODBB_DICDI
Sequence: MLRGNNIKKVNSLLVRSFHSTVGNRSGGPSTPINYPSLEIENAGEKQKMNLFQAINNGMDIAMQKDSKAVVFGEDVGFGGVFRCTVGLRDKYGASRVFNTPLCEQGIAGFAIGLAAQGATPIAEIQFADYIFPAFDQIVNEAAKYRYRSGGQFDCGSLTIRSPYGAVGHGGHYHSQSPESYFGHTPGLKVVIPSTPIEAKGLLLASIREKDPVIFFEPKLMYRSAVEEVPIGDYEIPLGKARIVKEGKDITIIGWGAQMRVLLQAVNMAEEKLGISCELIDLRTIQPWDVETVVESVKKTGRVVISHEAPKTGGWAAEISATIQERCFLHLEAPIQRVCGYDTPFPLIFEKFYVPDHLKNFESIKKTMVY
What is the function of this protein?
The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).  It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
What are the official names of this protein?
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial, 3-methyl-2-oxobutanoate dehydrogenase, Branched-chain alpha-keto acid dehydrogenase E1 component beta chain, BCKDE1B, BCKDH E1-beta.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: PDXJ_PORGI
Sequence: MTRLSVNVNKIATLRNARGGNVPDVLRVALDCERFGAQGITVHPRPDERHIRRSDVYDLKKALTTEFNIEGNPDERFIRLIEEIRPEQVTMVPDAPDVLTSNAGWDVARNYDHLCRLVERFHAWGIRTSIFIDTDLDNISWAAKTGTDRIELYTEPYAAAYHKDMAAAVQPYVKASVHAHSLGLGINAGHDLNLDNLRYFAERLPYLDEVSIGHALIADALYLGLEETIRQYRDQLAL
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSXB_SALCH
Sequence: MNTIWIAVGALTLLGLVFGAILGYASRRFAVEDDPVVEKIDAILPQSQCGQCGYPGCRPYAEAVGLQGEKINRCAPGGEAVMLKMAELLNVEPQPCDGEEQQAAPVRMLAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTHCIELRPVNETPDSWKWDLNTIPVRIIPVEQHA
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit B, Rsx electron transport complex subunit B.
What is the protein family that this protein belongs to?
Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane.
Protein: RL5_SINMW
Sequence: MAKSAYEPRLKKEYVERIRKAIQEQFSYANEMQIPRLDKIVINMGVGEATGDSKKPTVAAADLAAIAGQKPVITRARNSIAGFKLREGMPIGAKVTLRGVRMYEFLDRLINIALPRVRDFRGLNPKSFDGRGNFAMGIKEHIVFPEINYDKVDQMWGMDIIVCTTATNDDEARALLKEFNFPFRQ
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: VKT5_OXYMI
Sequence: MSSGGLLLLLGLLTLWEVLTPVSSKDRPKFYELPADIGPCEDFTGAFHYSPREHECIEFIYGGCEGNANNFNTLEECET
What is the function of this protein?
Serine protease inhibitor.
What are the official names of this protein?
Kunitz-type serine protease inhibitor microlepidin-5.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family.
What are the subcellular locations of this protein?
Secreted.
Protein: CWH43_YEAST
Sequence: MLIINGKIIPIAHTICAFSAFFAALVTGYSLHFHKIVTNAHYTYPDEWFPSVSATIGDRYPERSIFQILIALTAFPRFLLLLGHYYLNQSKVCFLVGVLRTVSCGGWVYITSTDDHDIHDIFMITYIVLTLPWDIMITRYSSPLTSKNKGLTATIFFGTLFPMIYWYIQHSVQQRAGAYSIYAYFEWSLILLDIAFDAFAYADFKKIDIVLAFNEKPGNTSFFQIRDSSPINYGEEKSSELQKSGEKKVEKEKPVARSATGSYFRFDSFFYLLTNIFNGFLFWSNVTSLLCSIWHFPLWYMGISGYEAAILGYLGPIFLYLPFVSEAFTQYGVLLGGIIAIGAYIVQMPELRLISVAVGTSITVATFVQNLRYITNAETSFSFALTWLLGLVASVILKMGFYTNNPTWVILDERNGGYNKTALVLTVLFGMLSPYVNSINFEGKRNAQAKSASLIGKLFLAVGFGSLLFGIHQLLTDSSTTIYWAWEGYNESHGPLPWPWGALTCTVMLFASLSSVKFMGKPLVPCLLLLISTAVLSARSITQWPKYIFGGLLYAIAMLWLVPSYFSALGQVQNIWVYVLSFSVYIIFVLAHVWVVAYAFVPMGWVLREKIETVLAFSSTFIIIGALTCKNLNIQLVTMGKKFFIYVFFFAVALLSLTARFVYDIRPTGIPQPYHPDSQLITAGIWTIHFGLDNDMWASEDRMINLIKDMELDVVGLLETDTQRITMGNRDLTSKLAHDLNMYADFGPGPNKHTWGCVLLSKFPIVNSTHHLLPSPVGELAPAIHATLQTYNDTLVDVFVFHSGQEEDEEDRRLQSNYMAKLMGNTTRPAILLSYLVVDPGEGNYNTYVSETSGMHDIDPSDDDRWCEYILYRGLRRTGYARVARGTITDTELQVGKFQVLSEQALVEHSDSMYEYGHMSEPEYEDMKFPDKFLGEGERGHFYHVFDEPRYYL
What is the function of this protein?
Involved in the maintenance of cell wall integrity.  Required for the replacement of the diacylglycerol moiety by ceramides during GPI-anchor maturation.
What are the official names of this protein?
Protein CWH43, Calcofluor white hypersensitive protein.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the PGAP2IP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Concentrates to the bud tip of small budded cells and to the neck of dividing cells.
Protein: PLSB_ECO55
Sequence: MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIESATQGEG
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: DHE3_CHICK
Sequence: CZAADKEDDPNFFKMVEGFFDRGASIVEDKLVEGLRTRQSMEQRRHRVRGILRIIKPCNHVLSVSFPIKRDDGZWEVIEGYRAQHSHQRTPCKGGIRYSLDVSVDEVKALASLMTYKCAVVDVPFGGAKAGVKINPKNYTDEDLEKITRRFTMELAKKGFIGPGVDVPAPNMSTGEREMSWIADTYASTIGHYDINAHACVTKPGISQGGIHGRISATGRGLFGHIENFIENASYMSILGMTPGFGDKTFAVQGFGNVGLHSMRYLHRFGAKCVAVGEFDGSIWNPDGIDPKELEDYKLQHGTIMGFPKAQKLEGSILETDCDILIPAASEKQLTKANAHKVKAKIIAEGANGPTTPQADKIFLERNIMVIPDLYLNAGGVTVSAFZZKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPVVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYVNAIEKVFKVYNEAGLTFT
What is the function of this protein?
Mitochondrial glutamate dehydrogenase that converts L-glutamate into alpha-ketoglutarate.  Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle.
What are the official names of this protein?
Glutamate dehydrogenase 1, mitochondrial, GDH 1.
What is the protein family that this protein belongs to?
Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion. Endoplasmic reticulum.
Protein: CATA1_SOLLC
Sequence: MDPSKYRPSSAYDTPFLTTNAGGPVYNNVSSLTVGPRGPVLLEDYYLIEKLATFDREKIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGAQTPVICRFSTVVHERGSPESIRDIRGFAVKFYTREGNFDLVGNNVPVFFNRDAKSFPDTIRALKPNPKSHIQENWRILDFFSFLPESLHTFAFFYDDVCLPTDYRHMEGFGVHAYQLINKEGKAHYVKFHWKPTCGVKCMSEEEAIRVGGTNHSHATKDLYDSIAAGNYPEWKLFIQTMDPEDVDKFDFDPLDVTKTWPEDLLPLIPVGRLVLNRNIDNFFAENEQLAFNPGHIVPGIYYSEDKLLQTRIFAYADTQRHRIGPNYMQLPVNAPKCGHHNNHRDGAMNMTHRDEEVDYLPSRFDPCRPAEQYPIPSCVLNGRRTNCVIPKENNFKQAGERYRSWEPDRQDRYINKWVESLSDPRVTHEIRSIWISYLSQADKSCGQKVASRLTVKPTM
What is the function of this protein?
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
What are the official names of this protein?
Catalase isozyme 1.
What is the protein family that this protein belongs to?
Belongs to the catalase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: Y2723_MYCTO
Sequence: MGASGLVWTLTIVLIAGLMLVDYVLHVRKTHVPTLRQAVIQSATFVGIAILFGIAVVVFGGSELAVEYFACYLTDEALSVDNLFVFLVIISSFGVPRLAQQKVLLFGIAFALVTRTGFIFVGAALIENFNSAFYLFGLVLLVMAGNLARPTGLESRDAETLKRSVIIRLADRFLRTSQDYNGDRLFTVSNNKRMMTPLLLVMIAVGGTDILFAFDSIPALFGLTQNVYLVFAATAFSLLGLRQLYFLIDSLLDRLVYLSYGLAVILGFIGVKLMLEALHDNKIPFINGGKPVPTVEVSTTQSLTVIIIVLLITTAASFWSARGRAQNAMARARRYATAYLDLHYETESAERDKIFTALLAAERQINTLPTKYRMQPGQDDDLMTLLCRAHAARDAHM
What are the official names of this protein?
Uncharacterized membrane protein MT2795.
What is the protein family that this protein belongs to?
Belongs to the TerC family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MIAB_BAUCH
Sequence: MNLKLHIKTYGCQMNQYDSSKIVDLLKNTHKYQLTDIAEEADILLLNTCSIREKAQEKLFHQLGRWRRLKKINPNLIIGVGGCVASQEGSNIRERANYVDIIFGPQTLHRLPEMINHVRITRSPVIDISFPEIEKFDCMPKPQAKGPTAFVSIIEGCDKYCSYCVVPYTRGIEVSRPCEDILLEINNLADQNVREIHLLGQNVNAYRGTRYGGGTCTFAELLRLVAAINGIDRIRFTTSHPIEFTDDLIDVYRDTPELVSFVHLPVQSGSDRILALMKRGHTVLEYKSIIRKLYAVRPSIQISSDFIVGFPGETEEDFRQTMNLISEVNFDMSFSFIYSPRPGTPAANMVDIVSQDEKKQRLYILQECIRKQAMKFSQAMKGTVQCILVEGTSRKNIMHLSGRTENNRVVNFIGNNGMIGQFVNVEIIDVYSNSLRGELISNQEKKYTLSA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.