PharMolix/UniProtQA huggingface dataset:
Protein: ATPG_CHESB
Sequence: MPSLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQEAAEAARPYAERMDAVLANVSASISGADAPPLMAGTGKDDVHLVVVCTADRGLAGSFNSQIARLAREHIRKLQANGRQVKIITVGKKGYDLLRRDFGKLVIDRIELREVKQIGFANADAIAKKVIGLFEAGEFDVCTLIYSRFKSVISQIPTEQQIIPAAVPQAEGESTGAIYEYEPDAGAILADLIPRNIAVQIFRALLENAAGEMGAKMTAMDNATRNAGEMINKLTITYNRQRQAQITKELIEIISGAEAL
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ROT1_KLULA
Sequence: MRVLIPLSLFAVAVSGQNSDLEGTWSSKSNQVFTGPGFYDPIEELLIEPALPGISYSFTADGYFEEAMYQVSGNPQDPKCPVAVLIFQHGTYEVKDDGQLVLTPIEVDGRQLLSQPCDDEGVSTYSRYYQAESFKSYLVQLDTYYGKQSLQLYGSDGAPLQPLFLAYKPPVMLPTITLNPTASDDAQPTSNAKRDLISHVRRSIENRHKTNAVKKTAPNIEKYWWGSLALIGVGSIAFLLS
What is the function of this protein?
Required for normal levels of the cell wall 1,6-beta-glucan.  Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity).
What are the official names of this protein?
Protein ROT1.
What is the protein family that this protein belongs to?
Belongs to the ROT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: CYC_GINBI
Sequence: ATFSEAPPGDPKAGEKIFKTKCAZCHTVZKGAGHKQGPNLHGLFGRQSGTTAGYSYSTGNKNKAVNWGZZTLYEYLLNPKKYIPGTKMVFPGLKKPZZRADLISYLKQATSQE
What is the function of this protein?
Electron carrier protein.  The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase.  Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
What are the official names of this protein?
Cytochrome c.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space. Note=Loosely associated with the inner membrane.
Protein: MRP_RAT
Sequence: MGSQSSKAPRGDVTAEEAAGASPAKANGQENGHVKSNGDLTPKGEGESPPVNGADEAAGATGDAIEPAPPSQEAEAKGEVAPKETPKKKKKFSFKKPFKLSGLSFKRNRKEGGGDSSASSPTEEEQEQGEISACSDEGTAQEGKAAATPESQEPQAKGAEASAVSKGGDAEEEAGPQAAEPSTPSGPESGPASASAENE
What is the function of this protein?
Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation.  When unphosphorylated, induces cell migration.  When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration.  May be involved in coupling the protein kinase C and calmodulin signal transduction systems.
What are the official names of this protein?
MARCKS-related protein, Brain protein F52, MARCKS-like protein 1, Macrophage myristoylated alanine-rich C kinase substrate, Mac-MARCKS, MacMARCKS.
What is the protein family that this protein belongs to?
Belongs to the MARCKS family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Cell membrane; Lipid-anchor. Note=Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca(2+)/calmodulin. Colocalizes with F-actin at the leading edge of migrating cells.
Protein: COLA_CLOPE
Sequence: MKKNLKRGELTKLKLVERWSATFTLAAFILFNSSFKVLAADKKVENSNNGQITREINADQISKTELNNEVATDNNRPLGPSIAPSRARNNKIYTFDELNRMNYSDLVELIKTISYENVPDLFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTYTADDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQDGVVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTNSVIYNTKGYDAKNTEFYNRIDPYMERLESLCTIGDKLNNDNAWLVNNALYYTGRMGKFREDPSISQRALERAMKEYPYLSYQYIEAANDLDLNFGGKNSSGNDIDFNKIKADAREKYLPKTYTFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFMRVVQNDKALEEGNPDDILTVVIYNSPEEYKLNRIINGFSTDNGGIYIENIGTFFTYERTPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYGSWDFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSLLNNIDNLDVPLVSDEYVNGHEAKDINEITNDIKEVSNIKDLSSNVEKSQFFTTYDMRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKGEKTLEPGRYYLSVYTYDNQSGTYTVNVKGNLKNEVKETAKDAIKEVENNNDFDKAMKVDSNSKIVGTLSNDDLKDIYSIDIQNPSDLNIVVENLDNIKMNWLLYSADDLSNYVDYANADGNKLSNTCKLNPGKYYLCVYQFENSGTGNYIVNLQNK
What is the function of this protein?
Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens additionally digest collagen to aid in host colonization.  Has both tripeptidylcarboxypeptidase on Gly-X-Y and endopeptidase activities; the endopeptidase cuts within the triple helix region of collagen while tripeptidylcarboxypeptidase successively digests the exposed ends, thus clostridial collagenases can digest large sections of collagen (By similarity).
What are the official names of this protein?
Collagenase ColA, 120 kDa collagenase, Microbial collagenase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M9B family. Collagenase subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RUNX1_HUMAN
Sequence: MRIPVDASTSRRFTPPSTALSPGKMSEALPLGAPDAGAALAGKLRSGDRSMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKITVDGPREPRRHRQKLDDQTKPGSLSFSERLSELEQLRRTAMRVSPHHPAPTPNPRASLNHSTAFNPQPQSQMQDTRQIQPSPPWSYDQSYQYLGSIASPSVHPATPISPGRASGMTTLSAELSSRLSTAPDLTAFSDPRQFPALPSISDPRMHYPGAFTYSPTPVTSGIGIGMSAMGSATRYHTYLPPPYPGSSQAQGGPFQASSPSYHLYYGASAGSYQFSMVGGERSPPRILPPCTNASTGSALLNPSLPNQSDVVEAEGSHSNSPTNMAPSARLEEAVWRPY
What is the function of this protein?
Isoform AML-1L interferes with the transactivation activity of RUNX1.
What are the official names of this protein?
Runt-related transcription factor 1, Acute myeloid leukemia 1 protein, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit.
What are the subcellular locations of this protein?
Nucleus.
Protein: GIMA5_HUMAN
Sequence: MGGFQRGKYGTMAEGRSEDNLSATPPALRIILVGKTGCGKSATGNSILGQPVFESKLRAQSVTRTCQVKTGTWNGRKVLVVDTPSIFESQADTQELYKNIGDCYLLSAPGPHVLLLVIQLGRFTAQDTVAIRKVKEVFGTGAMRHVVILFTHKEDLGGQALDDYVANTDNCSLKDLVRECERRYCAFNNWGSVEEQRQQQAELLAVIERLGREREGSFHSNDLFLDAQLLQRTGAGACQEDYRQYQAKVEWQVEKHKQELRENESNWAYKALLRVKHLMLLHYEIFVFLLLCSILFFIIFLFIFHYI
What is the function of this protein?
Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity).  Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus.  Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation (PubMed:29382851).  Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity).  May promote the survival of mature T lymphocytes upon cytokine withdrawal (By similarity).  May regulate Ca(2+) homeostasis by modulating lysosomal Ca(2+) stores, preventing its accumulation in the absence of T cell activation (By similarity).  May play a role in mitochondrial DNA segregation in hematopoietic tissues (By similarity).  Is a regulator of liver endothelial cell homeostasis (By similarity).
What are the official names of this protein?
GTPase IMAP family member 5, Immune-associated nucleotide-binding protein 5, Immunity-associated nucleotide 4-like 1 protein, Immunity-associated nucleotide 5 protein, IAN-5, hIAN5, Immunity-associated protein 3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.
What are the subcellular locations of this protein?
Lysosome membrane; Single-pass type IV membrane protein. Endosome, multivesicular body membrane; Single-pass type IV membrane protein. Endosome membrane; Single-pass type IV membrane protein. Note=The mitochondrial localization originally reported was observed with C-terminally tagged protein and was not confirmed in later publications.
Protein: PCP_YERPE
Sequence: MRRVLITGFEPFGGERINPSWEVVKQMNDLMMGGVRIVARQLPCAFGEALTALNTAIDDVQPVLVLAIGQAGGRADITIERVAINVDDARIPDNLGNQPVDQPIIQEGPAAYFTRLPIKAMVQGIREAGIPASVSQTAGTYVCNHVMYGLLHRLNQFNNEVKGGFIHIPYLPEQAVDHPGAPSMSAQSVLVALELAISIALQIEHDLHITGGAVH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DEOC_BACC1
Sequence: MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDDELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_RICCN
Sequence: MLKSNNASETAAHKVGDKTAKKVFFRRRKGCPLSVPNAPVIDYKNPELLIKFVSEGGRMLPSRITNVCAKKQRKLNNAIKIARILALLPFVFQAK
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: VF79_ASFK5
Sequence: MNKTIEYQKEFLKENNQLLNIPIKKNILKEILQNDEQDTIITNCITKEVSINLDLIKNPKVLYSIYIMVVEYLKSINIT
What are the official names of this protein?
Uncharacterized protein D79L, pD79L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus D79L family.
Protein: DAPAT_CHLFF
Sequence: MRRNSNFSSLETNYLFSSIRQKIRSFREKHPEISIIDLSIGDTTQPLHASVIDTFSTSVRKLGNPKTYRGYGPELGLPALKEKLSEVCYRGKVSPEEIFISDGAKTDIFRLFSLFGPGKTIAVQDPSYPAYIDAAILAGARKIVKLPCTKETDFFPVIPQEENIDIFCLCSPNNPTGTVLNREQLKELIDYANSHGSIILFDAAYSAFISDPSLPTSIFEIPEARFCAIEINSFSKSLGFAGVRLGWNIVPKDLKYSDGSLIIRDWERFLCTTFNGASLPVQEAAIAGASLFPNLEAISKYRYNSSLLREALQKAEFVVHGGEHAPYLWVEVPSMIPDEDFFDFFLYQYHIAITPGKGFGSCGTGYVRFSSLGKSENIVAACQRLSQTSVYDRTVLSL
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.
Protein: MISP3_HUMAN
Sequence: METPIEREIRRSCEREESLRRSRGLSPGRAGRELVELRVRPVLNLPGPGPALPRALERARAGAQMQRDIEREAHRQAALARPAVPEPRARSPPQPLGELKRFFEAAAGSGSSAGAGDGAGPQRLPEPGGRPRSAVQGGCRVLGSAPPPFTPSLLEQEVRAVREREQELQRQRRSVYGTAEFKEPTPSLTASRGDGKLVVIWPPRRKVSENGLEQEERKP
What are the official names of this protein?
Uncharacterized protein MISP3, MISP family member 3.
What is the protein family that this protein belongs to?
Belongs to the MISP family.
Protein: GALA_RAT
Sequence: MARGSVILLAWLLLVATLSATLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEVEEGRLGSVAVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEQS
What is the function of this protein?
Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3.  This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
What are the official names of this protein?
Galanin peptides.
What is the protein family that this protein belongs to?
Belongs to the galanin family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL7_PSYWF
Sequence: MALSREDVLNAIAEMSVMDIVELISEMEEKFGVTAAAAVAAAPAAAAAGAAAAEEKDEFDVILASFGDKKVGVIKAVREATGLGLKEAKELVEGAPAPIKEGANKVEAEELKKKLEEAGATVELK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: RX106_HYAAE
Sequence: MSVRYAGLLLAAVAVSAHINEVNSIVFPGSLHIDNRNGHVQRDLRSADNGNEERNAILETLSNHLASAFGYLWTKEAQEMTNSAWSALRNKESSLPLYSEGVAREYIETAALNTLTAEHRLARAEAYMVSMIVALRGVENPESLRNSADNLQQFLINVWKTGKKQPAQVFELLEHVPYEEGNASLVNDSKFAIWMAYMGKTFDHQFKNWADVQHNEQLRIEGDKEKKGGPDYVEGTESRGKKRGQTEAPDLEPGLTPKQKRLKRMELQRVKKILLNINLMGIGRS
What is the function of this protein?
Secreted effector that suppresses pathogen-associated molecular pattern (PAMP)-triggered immunity (PTI) in host plants (PubMed:22072967, PubMed:30156022).  Binds to RCD1 and SRO1 transcription co-regulators to attenuate transcriptional activation of salicylic acid (SA)-induced defense genes and alters plant growth responses to light (PubMed:30156022).  Suppresses SA signal transduction but not SA levels (PubMed:30156022).
What are the official names of this protein?
Secreted RxLR effector protein 106.
What is the protein family that this protein belongs to?
Belongs to the RxLR effector family.
What are the subcellular locations of this protein?
Secreted. Host nucleus. Note=Co-opts the host cell's nuclear import system via its bipartite nuclear localization signal.
Protein: HJURP_HUMAN
Sequence: MLGTLRAMEGEDVEDDQLLQKLRASRRRFQRRMQRLIEKYNQPFEDTPVVQMATLTYETPQGLRIWGGRLIKERNEGEIQDSSMKPADRTDGSVQAAAWGPELPSHRTVLGADSKSGEVDATSDQEESVAWALAPAVPQSPLKNELRRKYLTQVDILLQGAEYFECAGNRAGRDVRVTPLPSLASPAVPAPGYCSRISRKSPGDPAKPASSPREWDPLHPSSTDMALVPRNDSLSLQETSSSSFLSSQPFEDDDICNVTISDLYAGMLHSMSRLLSTKPSSIISTKTFIMQNWNSRRRHRYKSRMNKTYCKGARRSQRSSKENFIPCSEPVKGTGALRDCKNVLDVSCRKTGLKLEKAFLEVNRPQIHKLDPSWKERKVTPSKYSSLIYFDSSATYNLDEENRFRTLKWLISPVKIVSRPTIRQGHGENRQREIEIRFDQLHREYCLSPRNQPRRMCLPDSWAMNMYRGGPASPGGLQGLETRRLSLPSSKAKAKSLSEAFENLGKRSLEAGRCLPKSDSSSSLPKTNPTHSATRPQQTSDLHVQGNSSGIFRKSVSPSKTLSVPDKEVPGHGRNRYDEIKEEFDKLHQKYCLKSPGQMTVPLCIGVSTDKASMEVRYQTEGFLGKLNPDPHFQGFQKLPSSPLGCRKSLLGSTAIEAPSSTCVARAITRDGTRDHQFPAKRPRLSEPQGSGRQGNSLGASDGVDNTVRPGDQGSSSQPNSEERGENTSYRMEEKSDFMLEKLETKSV
What is the function of this protein?
Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres.  Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres.  Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer.  Directly binds Holliday junctions.
What are the official names of this protein?
Holliday junction recognition protein, 14-3-3-associated AKT substrate, Fetal liver-expressing gene 1 protein, Up-regulated in lung cancer 9.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Chromosome, centromere. Note=Localizes in centromeres during late telophase and early G1, when CENPA nucleosomes are assembled. Localizes to nucleolus during S phase, nucleolus site being often related to storage.
Protein: PG076_VACCC
Sequence: MLVVIMFFIAFAFCSWLSYSYLRPYISTKELNKSR
What is the function of this protein?
Component of the entry fusion complex (EFC), which consists of 11 proteins.  During cell infection, this complex mediates entry of the virion core into the host cytoplasm by a two-step mechanism consisting of lipid mixing of the viral and cellular membranes and subsequent pore formation.
What are the official names of this protein?
Entry-fusion complex protein OPG076, EFC protein OPG076, Protein O3.
What is the protein family that this protein belongs to?
Belongs to the orthopoxvirus OPG076 family.
Protein: METJ_SHIBS
Sequence: MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
What is the function of this protein?
This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.
What are the official names of this protein?
Met repressor, Met regulon regulatory protein MetJ.
What is the protein family that this protein belongs to?
Belongs to the MetJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMN6_SHEWM
Sequence: MAFTFKQFHIDDHGCGMPVSTDGVLLGAWAPLSKAENLLDIGAGSGLLSLMAAQRSEAQITAVELDDTAFHACNKNFIASKWQSRLNLVYASVQEFCNQHTDGNNAQFDHIICNPPYFKGGTQSSNRLRAQARHTDSLTFHALLEVITKLLAATGTASLILPSQSMTPFIEEVEKSELWMNQLTNISDSRFKAPHRHLFTLKHKATKLAEDDTVITNNLCIKEPDASYTPEMIALITGFYLKY
What is the function of this protein?
Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).
What are the official names of this protein?
tRNA1(Val) (adenine(37)-N6)-methyltransferase, tRNA m6A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOC2B_DROYA
Sequence: MDHVKLVNDPIDIAHIHQLLADEGCGASSVFVGTTRDNFQGKKVVSLAYEAYDSMALKEMNKICSDLRSKWPDLKHIVIYHRLGTVPVCEASVVIAASSPHRSEALESVSFAIDQLKTRVPIWKKEIYEGDYDSEWKENKESIRPKKSQSAFNYAACPCKVEESHDVPRTLVQIRVNDAELTKRLECFVNRKRDEINSQNVIDFKSSFVNSDKDFSDSCARTQSTIIKQEQSNSHLKVRRVNNRCGPQQMEMRPNYELELNKLMGSRDGQTDPSKEMRKSLPNSRLQAIESYMCLTTDNEENIFSRIKKVENRLLQLESISPEYRHFTKLEPSSMEPPPPKKIRKKSYSAQELSAFIQKIKDGSEFT
What is the function of this protein?
Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin.  Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated Mocs2A into precursor Z to generate a dithiolene group.
What are the official names of this protein?
Molybdopterin synthase catalytic subunit, Molybdenum cofactor synthesis protein 2 large subunit, Molybdenum cofactor synthesis protein 2B, MOCS2B.
What is the protein family that this protein belongs to?
Belongs to the MoaE family. MOCS2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSIE_SALPK
Sequence: MMPLSRSRLEFIATILQNVLNLGLLTLGLILIVFLGKETVHLADALFVPEQASKYELVEGLVIYFLYFEFIALIVKYFKSGLHFPLRYFVYIGITAIVRLIIVDHKTPMDVLLYSAAILLLVITLWLCNSNRLRRE
What are the official names of this protein?
Protein PsiE.
What is the protein family that this protein belongs to?
Belongs to the PsiE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DI3L1_MOUSE
Sequence: MLQKREKVLLLRTFQGRTLRIVREHYLRPSVPCNSPLCPQPAACRNDGKLLAAEVTHYVIPDWKVVQDYLEVLEFPELKGVIFMQTACQAVQHQRGRRQYNKLRNLLKDARHDCVLFANEFQQHCYLPREKGEAMEKWQTRSIYNSAVWYYHHCEDRMPIVMVTEDEEAIQKYGSETEGVFVISFKNYLDNFWPDLKAAHDLCDSILQSRRERETESQETHGKEYPEHLPLEVLEAGIKSGRYIQGILNVNKHRAQIEAFVRLHGASSKDSGLVSDILIHGSKARNRSIHGDVVVVEMLPKSEWKGRTAALGENDSDDKASGESPSEPMPTGRVVGILQKNWRDYVVTFPSKEEVQSQGKNAQKILVTPWDYRIPKIRISTQQAEALQDFRVVVRIDSWEATSVYPNGHFVRVLGRIGDLEGEIATILVENSISVVPFSEAQMCEMPVNTPENPWKVSPKEEQERKDLRTTHLVFSIDPKGCEDVDDTLSVRTLNNGNLELGVHIADVTHFVAPNSYIDVEARTRATTYYLADRRYDMLPSILSADLCSLLGGVDRYAVSVMWELDKTSYEIKKVWYGRTIIRSAYKLFYEAAQELLDGNFSIVDDIPELKALDKQSQQAKLEELVWAIGKLTDIARHIRAKRDRCGALELEGVEVRVQLDDKKNIRDLIPKQPLEVHETVAECMILANHWVAKKIWESFPHQALLRQHPPPHQEFFSELRECAKAKGFFIDTRSNKTLADSLDSANDPKDPLVNKLLRSMATQAMSNALYFSTGSCAEEEFHHYGLALDKYTHFTSPIRRYSDIVVHRLLMAAISKDKKMEIKENLFSNKNLEELCRHINNRNRAAQRSQKQSTELFQCMYFKDRDAETEERCIADGVIYSIRTNGVLVFIPRFGIKGAAYLKNKDSLVISCGPEGSSEWKPGSLQRSQNKIISTTAGGQSVTFHLFDHVTVRISVQASRCHSDTIRLEIVSNKPYMIPNTELCHQSSLLKSELVKEVTRSVEEAQLAQEVKGKVIQEEHQEYCQTKGRSLYTLLEEIRDLALLDVSDSCAM
What is the function of this protein?
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  It seems to be involved in degradation of histone mRNA.
What are the official names of this protein?
DIS3-like exonuclease 1.
What is the protein family that this protein belongs to?
Belongs to the RNR ribonuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CAPSD_PMMVS
Sequence: MAYTVSSANQLVYLGSVWADPLELQNLCTSALGNQFQTQQARTTVQQQFSDVWKTIPTATVRFPATGFKVFRYNAVLDSLVSALLGAFDTRNRIIEVENPQNPTTAETLDATRRVDDATVAIRASISNLMNELVRGTGMYNQALFESASGLTWATTP
What is the function of this protein?
Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA.
What are the official names of this protein?
Capsid protein, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the virgaviridae capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: NDNF_XENLA
Sequence: MKLCRWYIALFLLPVCLQSQKLPTRDEELFQMQIRDKALFHDSSVIPDGAEISGYLFRDNPKRYFFVVEEDNTPLSVIVTPCDAPLEWKLTLQELPEEASGEGSGEPEPLEEQKQQIVNEEGTELFSYKGNDVEYFVSSSSPSGLYQLELISTEKDTHFKVYATTTPESDQPYPELPYDPRVDVTSLGRTTITLAWKPTPTSSVMKQPIQYCVVINKEHNFKSICAVEAKMIADDAFMMAPKPGIDFNPFDFAHFGFQSDNSAGKDRNFMPKVSSSKMLRQITKPKVDIQKFCIGNKNIFTVSDLKPDTQYYFDVFAVNAVTNMSTAYVGTFARTKEEAKQKTVELKDGKVTDVFIKRKGTKFLRFSPVSSHQKVTFSVHSCLDAIQIQVRRDGKLLLSQSVEGVRQFQLRGKPKAKYLIRLKGSKKGASMLKILATSKFNKQPFPSLPEDTRIKAFDKLRTCSSATVAWLGTQERNKFCIYKKEVDDDYTEEHKKRDQNQCLGPDTRKKSEKVLCKYFHSQNIHKAVTTETIKGLQPGKSYMLDVYVMGHAGHSVKYQSKIVKTRKFC
What is the function of this protein?
Secretory protein that plays a role in various cellular processes.  Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus.  Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system.  May also act through the regulation of growth factors activity and downstream signaling (By similarity).  Also regulates extracellular matrix assembly and cell adhesiveness (By similarity).  Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (By similarity).
What are the official names of this protein?
Protein NDNF.
What are the subcellular locations of this protein?
Secreted.