PharMolix/UniProtQA huggingface dataset:
Protein: KU80_YEAST
Sequence: MSSESTTFIVDVSPSMMKNNNVSKSMAYLEYTLLNKSKKSRKTDWISCYLANCPVSENSQEIPNVFQIQSFLAPVTTTATIGFIKRLKQYCDQHSHDSSNEGLQSMIQCLLVVSLDIKQQFQARKILKQIVVFTDNLDDLDITDEEIDLLTEELSTRIILIDCGKDTQEERKKSNWLKLVEAIPNSRIYNMNELLVEITSPATSVVKPVRVFSGELRLGADILSTQTSNPSGSMQDENCLCIKVEAFPATKAVSGLNRKTAVEVEDSQKKERYVGVKSIIEYEIHNEGNKKNVSEDDQSGSSYIPVTISKDSVTKAYRYGADYVVLPSVLVDQTVYESFPGLDLRGFLNREALPRYFLTSESSFITADTRLGCQSDLMAFSALVDVMLENRKIAVARYVSKKDSEVNMCALCPVLIEHSNINSEKKFVKSLTLCRLPFAEDERVTDFPKLLDRTTTSGVPLKKETDGHQIDELMEQFVDSMDTDELPEIPLGNYYQPIGEVTTDTTLPLPSLNKDQEENKKDPLRIPTVFVYRQQQVLLEWIHQLMINDSREFEIPELPDSLKNKISPYTHKKFDSTKLVEVLGIKKVDKLKLDSELKTELEREKIPDLETLLKRGEQHSRGSPNNSNN
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Appears to have a role in recruitment of telomerase and CDC13 to the telomere and the subsequent telomere elongation.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  KU70, of the KU70/KU80 heterodimer, binds to the stem loop of TLC1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching.
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 2, ATP-dependent DNA helicase II subunit Ku80, High affinity DNA-binding factor subunit 2, Yeast Ku80.
What is the protein family that this protein belongs to?
Belongs to the ku80 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: OVOS1_HUMAN
Sequence: MHVHVCVCLCVCIYTSSCVCACVHMCMRDALLAEGRGGGLAAADDFLYLECCKCFSQESQIAMVCQERSQNETYEVKMNNDTEACRATLNLEERRSVAIRSRENVVFVQTDKPTYKPGQKDVNGIAQFFLDTYTFTYPNITLKDPQNNRIFQRQNVTSFRNITQLSFQLISEPMFGDYWIVVKRNSRETVTHQFAVKRYVLPKFEVTVNAPQTVTISDDEFQVDVCAYNFGQPVQGETQIRVCREYFSSSNCEKNENEICEQFIAQVQTNLDIFTLLCSSFLTVMQISEKTSVFITQLLGTVNFENMDTFYRRGISYFGQLKFSDPNNVPMVNKLLQLELNDEFIGNYTTDENGEAQFSIDTSDIFDPEFNLKVRHQRTEECYLPSWLTPQYLDAHFLVSRFYSRTNSFLKIVPEPKQLECNQQKVVTVHYSLNSEAYEDDSNVKFFYLNGNFSFPISISADLAPAAVLFVYTLHPSGEIVADSVRFQVDKCFKHKVNIKFSNEQGLPGSNASLCLQAAPVLFCALRAVDRNVLLLKSEQQLSAESVSSLYNMVPSIEPYGYFYHGLNLDDGKEDPCIPQRDMFYNGLYYTPVSNYGDGDIYNIVRVRSLRILENIIQTVRTNFPETWMWDLVSVSSSGSANLSFLIPDTITQWEASGFCVNGDVGFGISSTTTLEVSQPFFIEIASPFSVVQNEQFDLIVNVFSYRNTCVEVSYIWECLPGKVNITVVAESKQSSACPNEGMEQQKLNWKDTVVQSFLVEFLFLGDILGLALQNLVVLQMPYGSGEQNAALLASDTYVLDYLKSTEQLTEEVQSKAFFLSILGYQRQLSFKNSDGSYSVFWQQSQKGSIWLSALTFKTLERMKKYVFIDENVQKQTLIWLSSQQKTSGCFKNDGQLFNHALRNALFCLEAALDSGVTNGYNHAILAYAFALAGKEKQVESLLQTLDQSAPKLSKRYYWERERKPKTEEFPSFIPWAPSAQTEKSCYVLLAVISRKIPDLTYASKIVQWLAQRMNSHGGFSSNQVINVGLILIAARGEEGLFSKDQNTVTFSSEGSSEIFQVNGHNRLLVQRSEVTQAPGEYTVDVEGHGCTFIQIFRYTGIRNKSSMVVIDVKMLSGFTPTMSSIEEVNNRSLIFQHKDSYIEYKRADSFPFSVEQSNLVFNIQPAPAMVYDYYEKGRQATAMP
What is the function of this protein?
Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism.
What are the official names of this protein?
Ovostatin homolog 1.
What is the protein family that this protein belongs to?
Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: YI068_YEAST
Sequence: MLYVISELFFFLVYRYCFSNSNTNRLIKVGSRSTPLASMLRRYSCNISVACCTIFFLSELLTSFLHFNIPTSKSMRESQYTSRYFCQISNMLSIGSQLRSMKNSITVKFCVISVSLLSLPSSTLTKS
What are the official names of this protein?
Putative uncharacterized protein YIL068W-A.
Protein: RLMM_XANOR
Sequence: MSGLLCYCRQGFEPELAAELSARAAFVGIAGYARTQRNDGYVLFVCDEAAQLAAKLQWRELIFARQKLVVIAELKGIDPKDRITPILAALEGQQRFGDLWVEHPDSDAGKPLAGLARSFGNALRPALRKAGLLTDKPQPRQPRLHICFLDGDHALLAVADSADSAPWPLGIPRLKLLPEAPSRSALKLDEALLTLLTPEEREALVKPGMRAADLGAAPGGWTWVLTRQHVHVTSVDNGPLRAHVLETGLVEHLRADGFHWKPAQPLDWMVCDMVEQPRRVAERMATWVREGWCRNTIFNLKLPMKKRWDETRLCLELFEQQAEKSLIVRAKQLYHDREEITVLAMRG
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QCR2_DEBHA
Sequence: MLSRVSARSYSSAAQSIKLTAREAPGNLSTLSVVVNNAGSKAGKSGVAHLLSKYNFLNNEAKSALRFTRESELLGGIVSSDVTRDSIVLKTQFLKQDLPYFVEALGNVLTKTSFRDHELPETVLPAAKAQNAEAQGSNAFKAFESLHEISFRKGLGNPLYYDGTSPISVDEIKQFASEAYNTSNVSVFGSGVNEGDLKKFIGESAFSALPAGSSKTTPVELHNGKESRIRAAGGSVALIGVPIKTADFAKYEVLSAAIGSTYLPGSSAPLSQIPGAISKVLKYQDAGLFVICVCNSDAAVVAQGVKAAKKAVDSVSASDLSSATKAAELAVALQSRFESPVDVKIDASAAKSPAKLSEFNYVAVGNVDLLPYANEL
What is the function of this protein?
Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol.  In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
What are the official names of this protein?
Cytochrome b-c1 complex subunit 2, mitochondrial, Complex III subunit 2, Core protein II, Ubiquinol-cytochrome-c reductase complex core protein 2.
What is the protein family that this protein belongs to?
Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: CBP4_MOROL
Sequence: QQQQCRQGQQTHQRQRVCQARRPAIQRCCQQLRNIQVQCR
What is the function of this protein?
Chitin-binding protein (PubMed:21675945).  Has antifungal activity against C. krusei, C. albicans, C. tropicalis and C. parapsilosis (PubMed:28634471).  Has antinociceptive and anti-inflammatory activity in mice (PubMed:21675945).
What are the official names of this protein?
Chitin-binding protein 4, Mo-CBP4.
Protein: RLMH_LEVBA
Sequence: MNIKFVVVGKLKEKYFKQGIAEYAKRLSRFCKFSIVEVPDEKAPENLSQAEMDRVMAEEGERILAKIKDREYVYALAILGKERSSEAFAKEIKDLTTYGHSDITFVIGGSLGLTPAVLKRADTQISFGKFTLPHQLMRLVLTEQVYRAFMINEGSPYHK
What is the function of this protein?
Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase H, 23S rRNA (pseudouridine1915-N3)-methyltransferase, 23S rRNA m3Psi1915 methyltransferase, rRNA (pseudouridine-N3-)-methyltransferase RlmH.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase RlmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THA10_HUMAN
Sequence: MPARCVAAHCGNTTKSGKSLFRFPKDRAVRLLWDRFVRGCRADWYGGNDRSVICSDHFAPACFDVSSVIQKNLRFSQRLRLVAGAVPTLHRVPAPAPKRGEEGDQAGRLDTRGELQAARHSEAAPGPVSCTRPRAGKQAAASQITCENELVQTQPHADNPSNTVTSVPTHCEEGPVHKSTQISLKRPRHRSVGIQAKVKAFGKRLCNATTQTEELWSRTSSLFDIYSSDSETDTDWDIKSEQSDLSYMAVQVKEETC
What are the official names of this protein?
THAP domain-containing protein 10.
Protein: YL509_MIMIV
Sequence: MRILRYVSDLHLEYIDCIDGKSALNSLWDFKKDPNDIYYLALLGDIGNPFDKSIKKFFQKISPIYDKIFYVPGNHEYYNLNKPYRSIDDFNSQLKNMCQEFPNIILMNNEIYELDDISFIGSTLWSNISESKSNHISKSINDYHLIKKIDNNKLTKITIDDTNKWNTESIDYILNQLKNSIKPLIILTHHAPLFSDNILGNYTADPCYINSLNNEAFHNDLSKILNQPIIAWLYGHTHYTSKFIYNGIIIATNQLGYSHERNNFNPYAYIDIDQLLIDNL
What are the official names of this protein?
Uncharacterized protein L509.
Protein: PCY1A_HUMAN
Sequence: MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYDISEDEED
What is the function of this protein?
Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.
What are the official names of this protein?
Choline-phosphate cytidylyltransferase A, CCT-alpha, CTP:phosphocholine cytidylyltransferase A, CCT A, CT A, Phosphorylcholine transferase A.
What is the protein family that this protein belongs to?
Belongs to the cytidylyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Endoplasmic reticulum. Nucleus. Note=It can interconvert between an inactive cytosolic form and an active membrane-bound form.
Protein: MURE_TROWT
Sequence: MTLQGKPYRLSDLIKQTGVRLTDCSNQFSDRFVSGITQIAQSVERDDIFVAFQGKTRHGVEFLDQVQSCAAVLTDNKGRHIMQSDCLPTRSTPILVTDSPRSDLIVLAKRVYPIDDIRIFGITGTNGKTSTMHIAAKLLEMMGISCGISTTIGSSASESDSCLTTPELCQLYARIFTAKQARADFFALEASSHAINRGRLGDIVLEVAAFTNLTPEHMEEHKNMEAYYQAKKALFLNKRSNSAVINIDTPYGIRLFKETGCSASVISENTKYGLDHKLFWQASVRRVGLSFGFTLISPSGYRVESSISLLGKAFALNTCMAIVILCNLGIDIERIDSVLRKAGGLKMVLPGRMEVFQTGNSPRVIVDHGHTVDAVETALVAAKSITRGRLITIINADGQRDPSKRKHLGQLCGAYSDKLFITDGHSRFENPAEIRRMILDGVEGPRRQVEQIPSMTQAVLAAIDIARSDDTVLCSGFGDDPYLDVLGKKIPYSLRDEVRRGLERFAQGT
What is the function of this protein?
Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramyl-tripeptide synthetase, UDP-MurNAc-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y709_ACTP2
Sequence: MADVKKQSFQDMLDYVHLYRLKNKLHRETADNDRKIRDNQKRVLLLDNLNQYINDSMTVEDIRAIIANMRDDYENRVDDYMIRNAELSKQRREIRQKMAAHKTSASEKSEK
What are the official names of this protein?
UPF0265 protein APL_0709.
What is the protein family that this protein belongs to?
Belongs to the UPF0265 family.
Protein: BH148_ARATH
Sequence: MASLISDIEPPTSTTSDLVRRKKRSSASSAASSRSSASSVSGEIHARWRSEKQQRIYSAKLFQALQQVRLNSSASTSSSPTAQKRGKAVREAADRALAVSARGRTLWSRAILANRIKLKFRKQRRPRATMAIPAMTTVVSSSSNRSRKRRVSVLRLNKKSIPDVNRKVRVLGRLVPGCGKQSVPVILEEATDYIQALEMQVRAMNSLVQLLSSYGSAPPPI
What is the function of this protein?
bHLH transcription factor that binds DNA on specific sequence 5'-CANNTG-3' in target gene promoters (PubMed:24009530).  Negatively regulates brassinosteroid signaling (PubMed:20023194).  Together with BHLH148/RITF1, regulates the transcription of several genes involved in the detoxification of reactive oxygen species (ROS) generated by salt (NaCl) stress.  Confers tolerance to salt and to the oxidative stress-inducing reagents hydrogen peroxide H(2)O(2) and methyl viologen (MV) (PubMed:24009530).
What are the official names of this protein?
Transcription factor bHLH148, ATBS1 interacting factor 2, Basic helix-loop-helix protein 148, AtbHLH148, bHLH 148, Protein RSA1 INTERACTING TRANSCRIPTION FACTOR 1, AtRITF1, Transcription factor EN 143, bHLH transcription factor bHLH148.
What are the subcellular locations of this protein?
Nucleus.
Protein: NU2M_PANTR
Sequence: MNPLAQPIIYSTIFTGTLITALSSHWFFTWVGLEMNMLAFIPILTKKMSPRSTEAATKYFLTQATASMILLMAILSNSMLSGQWTMTNTTNQYPSLMIMMAMAMKLGMAPFHFWVPEVTQGTPLMSGLLLLTWQKLAPISIMYQISSSLNVNLLLTLSILSIMAGSWGGLNQTQLRKILAYSSITHMGWMMAVLPYNPNMTILNLTIYIILTTTAFLLLNLNSSTTTLLLSRTWNKLTWLTPLIPSTLLSLGGLPPLTGFLPKWVIIEEFTKNNSLIIPTIMAIITLLNLYFYLRLIYSTSITLLPMSNNVKMKWQFEHTKPTPFLPTLITLTTLLLPISPFMLMIL
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: ATP23_ASPCL
Sequence: MSESQPGASSTTSNKCDSGFIPGDDTFTQWRNIFSILMGKMTDEGKEQFRVARDLRNEAADCKRCEDQRDYLLQYSPVIRYLSDNIRQLGGDLHSHNIYCRRCTNRKAGGFDPEYGILLCANEMKDQGHLEDTMAHEMIHAYDHLRFKVDWSNNLRHAACTEIRASSLSGECRWAREFFRRGQWKFTQQHQECVRRRAILSVRARPGCKDEAHAEKVVNEVWDSCFRDTRPFDEIYR
What is the function of this protein?
Has a dual role in the assembly of mitochondrial ATPase.  Acts as a protease that removes N-terminal residues of mitochondrial ATPase CF(0) subunit 6 at the intermembrane space side.  Also involved in the correct assembly of the membrane-embedded ATPase CF(0) particle, probably mediating association of subunit 6 with the subunit 9 ring (By similarity).
What are the official names of this protein?
Mitochondrial inner membrane protease atp23.
What is the protein family that this protein belongs to?
Belongs to the peptidase M76 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Associates loosely with the inner membrane.
Protein: SART3_CAEEL
Sequence: MSDVDMESGSDDSGMEDLDEEIQKIKQKMIDDSQSVVLANQLLILLRKNGDFDELDIKRRQFVEWAPLNPLNWKNWIEDFQNRKPEPSVAEVEEMFEKALFDENDVTIWVERAMYAYKVANDKNKKEDFKFCRDVCSKALENLGTRYDSGGHIWLIFLEYEMSYLKNSMNAPDYQRLADQVFALFERALHCPTDQLEDVYVLAEQFCTEFKQHHKLEELKKTYNSTMRQKEQLSKFEELIQQEETKKQGLKQFFDHEKKSGIPSRIKMAHERLVSELDDDEEAWIAYGAWADIELKLPQVAVKVYSRALRHCPYSFVLHQQALLAFERDRRPNEEIDALWERARSNVINSAEEGRSLYRTYAFLLRRRIHLTGSSDYSPMAEVFDEGAALLREWFSMAWDTTADYRQMQAYFYASLMKNMDKCRNIWNDILASGFGRFAGKWIEAVRLERQFGDKENARKYLNKALNSVSDNINEIYMYYVQFEREEGTLAELDLVLEKVNSQVAHRAIRPQKKVSEKPAPAPKSKQDHIQKRTSGGEPIVKKVKGDDGGFKAPLPPSNAKSSSAVSSSNASSTPAPGSFAVQKAAPGTEDARTIFVSNLDFTTTEDEIRQAIEGVASIRFARKANSDLVHRGFAYVVMENDQKAQQALLKDRVPVKGRPMFISANDPEKRVGFKFSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHKDGKPKGIAFVDFDTEASAQKCVASGDKLMLRERELEVALSNPPVKKDKSHGKPAAIGASLEEDGPRKGHAAKLQLVPRAITNKTPQITARLDAMDVSEGTSTSQPLSNDQFRKMFMKN
What is the function of this protein?
U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery (PubMed:25753661).  Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:25753661).
What are the official names of this protein?
Nuclear RNA-binding protein sart-3, U4/U6 snRNA-associated-splicing factor.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm.
Protein: TBH1_DROME
Sequence: MLKIPLQLSSQDGIWPARFARRLHHHHQLAYHHHKQEQQQQQQQQQQQQAKQKQKQNGVQQGRSPTFMPVMLLLLMATLLTRPLSAFSNRLSDTKLHEIYLDDKEIKLSWMVDWYKQEVLFHLQNAFNEQHRWFYLGFSKRGGLADADICFFENQNGFFNAVTDTYTSPDGQWVRRDYQQDCEVFKMDEFTLAFRRKFDTCDPLDLRLHEGTMYVVWARGETELALEDHQFALPNVTAPHEAGVKMLQLLRADKILIPETELDHMEITLQEAPIPSQETTYWCHVQRLEGNLRRRHHIVQFEPLIRTPGIVHHMEVFHCEAGEHEEIPLYNGDCEQLPPRAKICSKVMVLWAMGAGTFTYPPEAGLPIGGPGFNPYVRLEVHFNNPEKQSGLVDNSGFRIKMSKTLRQYDAAVMELGLEYTDKMAIPPGQTAFPLSGYCVADCTRAALPATGIIIFGSQLHTHLRGVRVLTRHFRGEQELREVNRDDYYSNHFQEMRTLHYKPRVLPGDALVTTCYYNTKDDKTAALGGFSISDEMCVNYIHYYPATKLEVCKSSVSEETLENYFIYMKRTEHQHGVHLNGARSSNYRSIEWTQPRIDQLYTMYMQEPLSMQCNRSDGTRFEGRSSWEGVAATPVQIRIPIHRKLCPNYNPLWLKPLEKGDCDLLGECIY
What is the function of this protein?
Converts tyramine into octopamine, a neurotransmitter involved in ovulation and locomotion (PubMed:14623230, PubMed:14978721, PubMed:8656284).  Functions in an amine-mediated Bacc-dependent signaling pathway that negatively regulates acute ethanol sensitivity (PubMed:23142736).
What are the official names of this protein?
Tyramine beta-hydroxylase.
What is the protein family that this protein belongs to?
Belongs to the copper type II ascorbate-dependent monooxygenase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PG187_VACCC
Sequence: MNFQGLVLTDNCKNQWVVGPLIGKGGFGSIYTTNDNNYVVKIEPKANGSLFTEQAFYTRVLKPSVIEEWKKSHNIKHVGLITCKAFGLYKSINVEYRFLVINRLGVDLDAVIRANNNRLPKRSVMLIGIEILNTIQFMHEQGYSHGDIKASNIVLDQIDKNKLYLVDYGLVSKFMSNGEHVPFIRNPNKMDNGTLEFTPIDSHKGYVVSRRGDLETLGYCMIRWLGGILPWTKISETKNCALVSATKQKYVNNTATLLMTSLQYAPRELLQYITMVNSLTYFEEPNYDEFRHILMQGVYY
What is the function of this protein?
Essential serine/threonine-protein kinase that plays different role in the viral life cycle.  Phosphorylates the host small ribosomal protein RACK1 thereby customizing the ribosomes to a state optimal for viral mRNAs (which contain poly-A leaders) but not for host mRNAs.  Facilitates viral DNA replication by inhibiting host BANF1, a cellular host defense responsive to foreign DNA.  Phosphorylates host BANF1 on serine and threonine residues; this leads to BANF1 relocalization to the cytoplasm, loss of dimerization and impaired DNA binding activity.  Indeed, BANF1 activity depends on its DNA-binding property which is blocked by VPK1-mediated phosphorylation.  Required for viral intermediate genes expression, probably by inhibiting host BANF1.  Modulates cellular responses via host JUN by two different mechanisms, either by direct phosphorylation or by modulation of upstream JIP1-MAPK complexes.  Seems to participate in the accumulation/processing of late proteins and thus in virion maturation.  In addition, inhibits B12 repressive activity on viral DNA replication via a phosphorylation-dependent mechanism.
What are the official names of this protein?
B1 kinase, Serine/threonine-protein kinase 1, Vaccinia protein kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Poxviruses subfamily.
Protein: PLSB_SHIB3
Sequence: MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGMLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASRAIAKAVEDEAHSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPSHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLTIESATQGEG
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, GPAT.
What is the protein family that this protein belongs to?
Belongs to the GPAT/DAPAT family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: EFTU_CHLL2
Sequence: MAKESYKRDKPHVNIGTIGHVDHGKTTLTAAITSVLAKQGLALQRDFGSIDKAPEERERGITISTAHVEYQTKKRHYAHIDCPGHADYIKNMITGAAQMDGAILVVAGTDGPMPQTREHILLARQVNVPALVVFLNKVDIADPELLELVELELRELLTEYNFPGDDIPIIKGSALKALDGDPEGEKAIMELMDAVDEFIPEPVRDVDKPFLMPVEDVFSISGRGTVGTGRIERGRIKINEEVEIVGIKPTRKSVVTGIEMFQKLLDEGQAGDNAGLLLRGVDKTELERGMVIAKPGSIKPHTKFKAEVYILRKEEGGRHTPFFNGYRPQFYFRTTDVTGSVTLPEGVEMVMPGDNLSVEVELIVPIAMDEGLRFAIREGGRTVGAGSVTKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIHI_ALIF1
Sequence: MSRIKKARKPGMSSQPVVVTRNRTDRDVESREIKRKRKRKGLKAGARNAESNAEQARRNAQKKDPRIGSKKPIQLVVEAKQKTTKQERRLTNEQELAMLENDAQLMVLLDRLDSGENLGTGLQKYVDEKLARIEHLMGRLGLLDDEEPEEIEEFPEFAERKAKSDDDLLAEFDDFNMDDFK
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: AGALG_EMENI
Sequence: MTNSKARYVLEPVQVTGTTFALNGTTLSYQFHVDEPSADLRSDHFGGSISGPIPVDPEPIVDGWTGMPDRVRREFPDQGRGDFRVPAFRIRQAEGHTVSAFRYREHEIVPGKEVSASGLPGVFGDAHDATTLIVRLVDPYSDLAAELKYTVFPKYDTVVRSASITNKSNSDVTIESLASLSVDFPFDELEMIGLRGDWAREAHRLRRKVDYGVQSFGSTTGFSSHLHNPFVALVHPSTTESQGEAWGFSLIYSGSFTINVEKSSQGLTRVSIGPSQLSWTLKPGETFDSPECVAVYSSTGIGGMSRSLHGLYRKHLMKSKFATEDRPVLLNSWEGLYFHIDQDRMYRLAQEAAALGVKLLVMDDGWFGDEHPRTSDDAGLGDWIPNPARFPDGLTPLVNRITALKVANSQRNMRFGIWVEPEMVNPRSTLYQQHPDWVLHAGNYPRTEQRNQLVLNMSLPEVQEFIISAMSEILNAADITYVKWDHNRGLAETPSPCANHAYMLGAYRVFDVLTTRFPNVIWEGCASGGGRFDPGILQYFPQVWTSDDSDAVERIFIQFGTSLAYPASAMGGHISSVPNHQTGRTTPLTFRAHVAMMCGSFGLELDPAHLTDSERRDIPGLIALAEKISPIVVKGDLWRLALPEDSNWPAALFLSENRTQGVLFFFQLAPMVNHSLPRVRLQGLEDGALYRVDGEGPYSGSMLMNLGLQYSFRGDYGSRLAFIERE
What is the function of this protein?
Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides (By similarity).  Not active on paranitrophenyl-alpha-galactoside and raffinose.
What are the official names of this protein?
Probable alpha-galactosidase G, Melibiase G.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 36 family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS6_CHLL3
Sequence: MLAKRIIPCLDVRDGRVVKGINFEGLRDAGSILEQARFYNNELADELVFLDISASLESRRTTLEEVLKVSGEVFIPLTVGGGINSVERAREVFLHGADKVSVNTAAVKEPELISRIAEKYGSQAVVVAIDIKKVDGRYIVHTHSGKQPTAYEALEWALKVQELGAGEILLTSMDRDGTKEGYDNDSLALISTAVHIPVIASGGAGSLEHLYDGFTKGHADAALAASIFHFRQHSIREAKQYLRDRGITVRL
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_CORGL
Sequence: MANPRNEAALAELKARFAETDTVVLTEYRGLTVAQTTELRKALGFDVQYSVAKNTLVKIAANEAGVEGLDDLLTGPTAVAFIKGEAVDTAKVLKKFGEENKAFVVKGGYMDGNALTAEQVNAIAELDNRETTLAKLAGAMKGSLAKAAGLFNAPASQVARLAVALQDKKDA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.