PharMolix/UniProtQA huggingface dataset:
Protein: KIB3_ARATH
Sequence: MSDSDGKNMEGRFEAAYIVDLVRLILERLSFVDFHRARCVSSTWYVASKSVIGVTNPTTPWIILFPNKNVENNGSCKLFDPHENKTYIIRDLGFDMSTSRCLASSGSWFLMFDHRADFHLLNLFTRERILLPSLESIDGERYMRFKRPISGSHIEIDKAVLWVDDKSRDYFVFCNLSSYVAYHHKRGDDNNSWKVLQPIKHQGCVDMVFKESKLYMISAHQCLTVFDFSGGVSPVEMECASFGSSVCVNRFHMKYFSNLAVTLSGEVLIIVGGKMDSSPEAKCVFTVNKMDPKSSEFTVLIKSIGDEALLLDLGITVPAKDGVMRDCIYFSNDQYHRCCGISLRDGYNADRICVYQIGSDYVVQEFEHLTTSSTKLFKDARWFFPTFGDKCCFHLWILHPVILQAKKLQKSNLKGTKPVTREKTTIVNNVDGTTTQREKTTKGKNMIGKK
What is the function of this protein?
Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.  Required for brassinosteroid (BR) signal transduction.  Mediates ASK7/BIN2/SK21 inactivation both by competing with substrate binding (e. g.  BZR1) and by promoting its ubiquitination and subsequent proteasomal degradation.
What are the official names of this protein?
F-box protein KIB3, Protein KINK SUPPRESSED IN BZR1-1D 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: DGTP_SALSV
Sequence: MASIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKEQNRLEEYGLDALTGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTHDRCVVSSLRLQEGEENLNDIRRKVRQDICHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGPVPDSHRYLMKKPGYYLSEEKYIARLRKELQLAPYSRFPLTWIMEAADDISYCVADLEDAVEKRIFSVEQLYHHLYHAWGHHEKDSLFELVVGNAWEKSRANTLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPQIFAGTFNQALLEDASGFSRLLELYKNVAVEHVFSHPDVEQLELQGYRVISGLLDIYQPLLSLSLNDFRELVEKERLKRFPIESRLFQKLSTRHRLAYVEVVSKLPTDSAEYPVLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVEQ
What is the function of this protein?
dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs.
What are the official names of this protein?
Deoxyguanosinetriphosphate triphosphohydrolase, dGTP triphosphohydrolase, dGTPase.
What is the protein family that this protein belongs to?
Belongs to the dGTPase family. Type 1 subfamily.
Protein: T255A_MOUSE
Sequence: MHQSLTQQRSSDMSLPDSMGAFNRRKRNSIYVTVTLLIVSMLILTVGLAATTRTQNVTVGGYYPGVILGFGSFLGIIGSNLIENKRQMLVASIVFISFGVIAAFCCAIVDGVFAARHIDLKPLYANRCHYVPKTSQREAEEVITSSSKITPSTRALRNLTQAVKEVNCPQLSRGLCTPRIRGNTCFCCDLYNCGNRVEITGGYYEYIDVSSCQDIIHLYHLLWSATILNIVGLFLGIITAAVLGGFKDMNPTLPALNCSVENAHPTVSYYARPQVASYNTYYHSPPHLPPYSAYDFQHSGVFPSSPPSGLSDEQEPQSPSPSPSYMWSSSAPPRYSPPYYPPFEKPPPYSP
What are the official names of this protein?
Transmembrane protein 255A, Protein FAM70A.
What is the protein family that this protein belongs to?
Belongs to the TMEM255 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: Y1339_STAAS
Sequence: MNELEFVTKHRRHLHQHPELSLHEFETTAYIKAFLDSLNIKYDCPLETGVIAYLEGNGSHTIAYRADIDALPILEENDVPYRSQSDHVMHACGHDGHTTALMLFVQRCKDMQDAGQLPQNVVFIFQPAEETGGGANRLIKAGAFDKYPIEAVFGIHVNPFADEGIAVIRDEEITASATEYRFFLTGLSSHVADKEQGHSCGEALQHVLTQISQIQQFHLNGLKRNIVHIGHFKAGEAINTVPSNGYLEGTIRTYDIDDLTIVKNQMHKIAESVKLLFNVDCEVKFAEGYPPTINSPKLRTQIEDALIKADLNVYDKPTPFLFGEDFSFYGQQLAPAYFVFIGTRNEDKGFVTGLHTSHLNFDEKVLINVVNFYENLLNNYKEV
What are the official names of this protein?
Uncharacterized hydrolase SAS1339.
What is the protein family that this protein belongs to?
Belongs to the peptidase M20 family.
Protein: POTE1_CHICK
Sequence: MPVQVLKIIKGKPETQLPSHLQREDLKHLQTGLDHTNKYFQGIVILSYPLTKLGDGTDFFKIVLQDDTCSRINSINVLMYGKMAEDCAKLIRNGDTFIVAGFKVAESPTAREDGRHACHLQVSEESGSAIFICTQPSITPFSEATSPSVAPKYVYTPLNCLKDGTVVNLYGIVKFFKPPYISKGTDYCSVVTLVDQSNVKLTCTLFNGNLDSLPKIYKNGDIVRFHRVKIREYNGQMQGITSAGFASLTFDGTVGAPVVPRASSKVYTFVDEEQKTVEELRIWAASNLSVSGPEAKLSDVKPMMFFDLTCQLVGKAKVDGSSFLLKVWDGTKCPYPTWKVPVEAKELEGDRVLLHHLRNLTVDVLVYDNHVQLAKSLKTGSFLRIYSIHTKQASAKNEDMSSHIEFHLHGGTCYGRGIGILPENNPDVEELKSFLECVELTDSQNMESVSSLELGDTFDSYTDLESPLQRCQQLSATVLTDHQDMSNTVLKTVLNSSAPQQYRIRAKLRSFKPQKLYQSVKLHCSKCNTLQEVPNGDAIDFILQGCAATAPNPELQSMSWYESVVWTTEEDQGRKITIHFVKHYEMLQRPENTLLMIEGGTLKEIWKLTRRFKCVIPVKSKEDDLELLDLSAPFLLQGNIKYYGCKKCSTPKSIKNLSSLAEKREPSWEPTEIAQVLGIEPLQYVFVMKFTLVDGTGVLNAYLFDYEKFFQIPASEILTNSFLQQKMEMTMNTLSPPGRKLDDLPWLECFIKSYNVADGMKHQVYYQIFDTTVAEDVV
What is the function of this protein?
Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini.  Is a component of the double-stranded telomeric DNA-binding TRF1 complex that is involved in the regulation of telomere length by cis-inhibition of telomerase.  Also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus.  Binds to at least two telomeric single-stranded 5'-TTAGGG-3' repeats (G-strand).  Its activity is TERT dependent but it does not increase TERT activity (By similarity).
What are the official names of this protein?
Protection of telomeres protein 1, cPot1, POT1-like telomere end-binding protein.
What is the protein family that this protein belongs to?
Belongs to the telombin family.
Protein: TLCD5_HUMAN
Sequence: MALALCLQVLCSLCGWLSLYISFCHLNKHRSYEWSCRLVTFTHGVLSIGLSAYIGFIDGPWPFTHPGSPNTPLQVHVLCLTLGYFIFDLGWCVYFQSEGALMLAHHTLSILGIIMALVLGESGTEVNAVLFGSELTNPLLQMRWFLRETGHYHSFTGDVVDFLFVALFTGVRIGVGACLLFCEMVSPTPKWFVKAGGVAMYAVSWCFMFSIWRFAWRKSIKKYHAWRSRRSEERQLKHNGHLKIH
What are the official names of this protein?
TLC domain-containing protein 5, Transmembrane protein 136.
What is the protein family that this protein belongs to?
Belongs to the TLCD5 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PVK2_PHYPD
Sequence: GASGLIAFPRL
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-2.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: FADX_TRIKI
Sequence: MGGGEGIEVRSGSSSTKLAFGERITHAKPPFSISQIKKAIPPHCFQRSLYRSFSYVIFDFIFASTFYHIAATNFHRLPHPLHYLAWPLYWFCQGSVFTGLWVIAHECGHRAFSDYQLVDDVVGFLLHTSFLIPYFSFKISHRRHHSNTASLERDEVFVPKPKAKMPWYFKHLTNPPARVLIIFITLTLGWPMYLAFNISGRFYERFTSHFDPNSPIFSENEWLQVHISNAGIVAVWYLLYKLAAAKGIAWVIRMYVVPVTIMNAFVVLITSLQHTHPSFPYYDSTEWNWLRGNLVTLDRDYGILNKVFHNITDTHVVHHLFPSMPHYNAMEATRAVKQVLGEYYHFDGTPIFKAAWREFRECIYVEPDNDEGASSSSKGVFWFRNKL
What is the function of this protein?
Converts a single cis double bond at position 12 of linoleate incorporated into phosphatidylcholine into conjugated 11-trans and 13-cis double bonds (PubMed:12464604).  16:2(9Z,12Z), 18:3(9Z,12Z,15Z) and 18:2(9Z,12Z) are substrates for the conjugase to form trans-Delta(11) and cis-Delta(13) double bonds (PubMed:12464604).  No activity on the cis-Delta(9) double bonds of oleic and palmitoleic acids (PubMed:12464604).
What are the official names of this protein?
Bifunctional fatty acid conjugase/Delta(12)-oleate desaturase, TkFAC, Delta(12)-oleate desaturase, Linoleoyl-lipid Delta(12) conjugase (11E,13Z-forming).
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DAPAT_METJA
Sequence: MESYIQNLFAERIGGKKFGKEDVIYKFEKIKRAKQEAMKRHPDMELIDMGVGEPDEMADPEVIRVLCEEAKKWENRGYADNGIQELKDAVPPYMEKVYGVKDIDPVNEVIHSIGSKPALAYITSAFINPGDVCLMTVPGYPVTATHTKWYGGEVYNLPLLEENDFLPDLESIPEDIKKRAKILYLNYPNNPTGAQATKKFYKEVVDFAFENEVIVVQDAAYGALVYDGKPLSFLSVKDAKEVGVEIHSFSKAFNMTGWRLAFLVGNELIIKAFATVKDNFDSGQFIPIQKAGIYCLQHPEITERVRQKYERRLRKMVKILNEVGFKARMPGGTFYLYVKSPTKANGIEFKTAEDFSQYLIKEKLISTVPWDDAGHYLRLAACFVAKDENGNPTTEEKYEDMVLEEFKRRLEGMDLEFE
What is the function of this protein?
Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis.  Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E. coli.
What are the official names of this protein?
LL-diaminopimelate aminotransferase, DAP-AT, DAP-aminotransferase, LL-DAP-aminotransferase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDL27_ARATH
Sequence: MDRISQLSDDLLLQILSFIPGKDVVATSLLSKRWQSLWMLVSELEYDDSYHTGDYKSFSQFVYRSLLSNNAPVIKHLHLNLGPDCPAIDIGLWIGFALTRRLRQLKINIRTSSNDASFSLPSSLYTSDTLETLRLINFVLLDVPSSVCLPSLKVLHLKTVDYEDDASLPSLLFGCPNLEELFVERHDQDLEMDVTFVVPSLRRLSMIDKNYGQCDRYVIDVPSLKYLNITDDAVYDVRQIENMPELVEAHVDITQGVTHKFLRALTSVRQLSLCLSLSEVMCPSGIIFSQLVHLNLSTVVKGWWDLLTSMLQDSPKLQSLKLIDKQHESGLCGIETPIGWKLPSSVPECLLFSLEAFEWIGYKGRRGDREVATYVLKNAACLRTAKFSPESTDVGEKYHMLKELASVPTASTSSKLLFD
What are the official names of this protein?
F-box/FBD/LRR-repeat protein At4g26340.
Protein: LYG_TAKRU
Sequence: MPYGKIEDIKTSGASDVTAAQDGLKEGGWKSSHRMAEIDSNRMENYRTIINEAGRQCDVDPAVIAGIISRESRAGNQLINGWGDHGKAFGLMQIDVTPPPNGGGHTPVGTWDSLEHLIQATEILVEFIERIKTKFPRWNADQHLKGALAAYNKGEKNVESYASVDAKTTGKDYSNDVVARAQWYKSNMGF
What are the official names of this protein?
Lysozyme g, 1,4-beta-N-acetylmuramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 23 family.
Protein: RP18_FOWPN
Sequence: MSLFNTNAYLPVVIQPHELNLDLMDNIKKAVINKYLHKETSGFMAKKIQIVEDTPMPLAELVNNEIVVHVTCNIDYKYYKVGDIVSGILTITDESDISVVCSDLICKIRSDSGTVSYDNSKYCFIKNGKVYANESTVTVMLKEAQSGMESSFVFLGNIIEK
What is the function of this protein?
Part of the DNA-dependent RNA polymerase which catalyzes the transcription of viral DNA into RNA using the four ribonucleoside triphosphates as substrates.  Responsible for the transcription of early, intermediate and late genes.  DNA-dependent RNA polymerase associates with the early transcription factor (ETF) thereby allowing the early genes transcription.  Late transcription, and probably also intermediate transcription, require newly synthesized RNA polymerase (By similarity).
What are the official names of this protein?
DNA-directed RNA polymerase 18 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the poxviridae DNA-directed RNA polymerase 18 kDa subunit family.
What are the subcellular locations of this protein?
Virion. Note=All the enzymes and other proteins required to synthesize early mRNAs are packaged within the virion core along with the DNA genome. This is necessary because viral early mRNAs are synthesized within minutes after virus entry into the cell and are extruded through pores in the core particle (By similarity).
Protein: RL24_STRPJ
Sequence: MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKHQRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MINE_CLOB6
Sequence: MDLFKFFSKQSSKDVAKERLKLILIQDRNSISPDVLESIREDMLKVISKYIEIDNEDVDIKMSSVEEIEGMSPALIASIPIKRIKKK
What is the function of this protein?
Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites.  This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.
What are the official names of this protein?
Cell division topological specificity factor.
What is the protein family that this protein belongs to?
Belongs to the MinE family.
Protein: FZD8_XENLA
Sequence: MESLSLSLLLLVSWLQGSQCAAAKELSCQEITVPLCKDIGYNYTYMPNQFNHDTQDEAGMEVHQFWPLVVIHCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERARAGCAPLMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYYNRTEQTTAAPSHPEPPKPPARSVPKGRTRVEPPRSRSRATGCESGCQCRAPMVQVSNERHPLYNRVRTGQIPNCAMPCHNPFFSPEERTFTEFWIGLWSVLCFASTFATVSTFLIDMERFKYPERPIIFLSACYLLVSTGYLIRLIAGHEKVACSRGELDLEHIIHYETTGPALCTLVFLLIYFFGMASSIWWVILSLTWFLAAGMKWGNEAIAGYSQYFHLAAWLVPSIKSIAVLALSSVDGDPVAGICFVGNQNLDNLRGFVLAPLVIYLFIGSMFLLAGFVSLFRIRSVIKQGGTKTDKLEKLMIRIGIFSVLYTVPATIVVACFFYEQHNRQGWEVAHNCNSCQPEMAQPHRPDYAVFMLKYFMCLVVGITSGVWIWSGKTLESWRAFCTRCCWGSKATGGSMYSDVSTGLTWRSGTGSSVSCPKQMPLSQV
What is the function of this protein?
Receptor for Wnt proteins.  Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.  A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase.  Both pathways seem to involve interactions with G-proteins.  May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.  Activation by Wnt8, Wnt5A or Wnt3A induces expression of beta-catenin target genes.  Displays an axis-inducing activity.
What are the official names of this protein?
Frizzled-8, Fz-8, Xfz8.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor Fz/Smo family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: AIM21_KLULA
Sequence: MEQVIPKVPERPRRRITRSEEPEQLRSESEFEREKSGSKDSELDLPPVPKTRPNRKPLASSSAHASSDDVSVKPEPQIQAQLQPEAVIETEPTVEHPIVDELEAKLPVEQPVLDEVELDEPVTQEVEPSGELLPEESTIKESLEEQIIDDFADEPVEEECKEVASPELIGDEAIQDEELEKPVKEEPIIQTDDKTLAEAIVPSVCEESEADIAEEPKETPEDASEAVVEAAREESSEVSPEASPEVPPEKTQVSVDQLSSTANLTEGAKEAPKEEQKETSEATSEETPEDSSVNAKPLFKEVTPGNVSSKEAIPSNTSPKEGSPATQKKKQGKSPPVPKKPSSKIAAFQQMFQNQQLQPEHTPSPKEPAAPKTGGFSGNRAQFAQNLNGMIALPGMAQLTPALAKRLGVSTSSDDAETGAEVETKNTKDEAELPKVPARSKKTRGPHKRLPKTVASIEKVETKSTSNISVVKAWTISFKPDLPERADDQPMEAELTAGEAIAPSEPAGLEDVEAEDLNEASPEEPLQIISESGNSDESEIQHTSDPSIAQNVEHEEEVHEEAEAAPEAEPEAEEIALDTEESNPTAFIAETYDEDTEVETPTA
What is the function of this protein?
Involved in mitochondrial migration along actin filaments.
What are the official names of this protein?
Altered inheritance of mitochondria protein 21.
What is the protein family that this protein belongs to?
Belongs to the AIM21 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.
Protein: SSPI_BACMK
Sequence: MSFNLRGAVLANVSGNSQDQLQETIVDAIQSGEEKMLPGLGVLFEVIWKNADENEKHEMLGTLEQGLKK
What are the official names of this protein?
Small, acid-soluble spore protein I, SASP I.
What is the protein family that this protein belongs to?
Belongs to the SspI family.
What are the subcellular locations of this protein?
Spore core.
Protein: SERC_STUST
Sequence: MSKRAFNFCAGPAALPEAVLQRAQAELLDWQGRGLSVMEMSHRSDAYVAIAEKAEQDLRDLMAIPSDYKVLFLQGGASQQFAEIPLNLLPEGGVADYVDTGIWSRKSIEEARRFGNVNLAASAKPYDYFAISGQNDWQLSDNAAYLHYASNETIGGLQFDWVPELGDTPLVVDMSSDILSRAIDVSKFGLIYAGAQKNIGPSGLVVVIVRDDLLGKARSSCPTMLDYKIAADNGSMYNTPATFSWYLSGLVFEWLKEQGGVEVMEQRNRAKKELLYGFIDASEFYTNPIAENARSWMNVPFRLADERLDKAFLAGADARGLLNLKGHRSVGGMRASIYNAVGLDAVEALVAYMAEFEKEHG
What is the function of this protein?
Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
What are the official names of this protein?
Phosphoserine aminotransferase, Phosphohydroxythreonine aminotransferase, PSAT.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
Protein: HCP3_CAEEL
Sequence: MADDTPIIEEIAEQNESVTRIMQRLKHDMQRVTSVPGFNTSAAGVNDLIDILNQYKKELEDDAANDYTEAHIHKIRLVTGKRNQYVLKLKQAEDEYHARKEQARRRASSMDFTVGRNSTNLVDYSHGRHHMPSYRRHDSSDEENYSMDGTNGDGNRAGPSNPDRGNRTGPSSSDRVRMRAGRNRVTKTRRYRPGQKALEEIRKYQKTEDLLIQKAPFARLVREIMQTSTPFGADCRIRSDAISALQEAAEAFLVEMFEGSSLISTHAKRVTLMTTDIQLYRRLCLRHL
What is the function of this protein?
Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:10524621).  Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation (PubMed:11402065, PubMed:14522947, PubMed:16273096, PubMed:16950114, PubMed:16950115, PubMed:12080088, PubMed:15767665).  May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity).  Might promote cleavage furrow stability during cytokinesis (PubMed:23684975).  Not required for chromosome segregation during meiosis (PubMed:16273096).
What are the official names of this protein?
Histone H3-like centromeric protein hcp-3, CENP-A homolog, CeCENP-A, Holocentric chromosome-binding protein 3.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Chromosome, centromere, kinetochore. Note=Requires knl-2 and lin-53 for chromatin localization (PubMed:17339379, PubMed:26904949). Co-localizes with hcp-6 at prophase, metaphase, and anaphase chromosomes (PubMed:12080088, PubMed:15767665).
Protein: MFNA_METTP
Sequence: MYTFPEKGLSEDMVTDLLKEMRSRDCPYDRLLSTMCTRPHPVAVRAYSMFLETNLGDPGLFPGTAEIERRVVGILGSLLGCSDATGYVSTGGTESNIQAVRAARNSSGRRDGNIVVPRSAHFSFDKIADLLNLEVRKAELDESLRVDVGDVERLIDDRTVCLVGIAGTTEFGQVDPIGDLSELAIENGIPLHVDAAFGGFVLPFLEKDCMWDFRAEGVQSITIDPHKMGMSPIPAGGLIFRSSDPLRRLETETYYLTVSRQASLTGTRSGAAAAATYAVIMHLGIDGYRKVVRRCMDMTEHLVSEARAMGIEPVIEPVMNVVALRVDDPPGVRRALLERGWHVSMTREPKALRLILMPHMTDENLDLFLSDLEDVLISLRRGG
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: CIA2B_HUMAN
Sequence: MVGGGGVGGGLLENANPLIYQRSGERPVTAGEEDEQVPDSIDAREIFDLIRSINDPEHPLTLEELNVVEQVRVQVSDPESTVAVAFTPTIPHCSMATLIGLSIKVKLLRSLPQRFKMDVHITPGTHASEHAVNKQLADKERVAAALENTHLLEVVNQCLSARS
What is the function of this protein?
Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004, PubMed:22678362, PubMed:22678361, PubMed:29848660).  As a CIA complex component and in collaboration with CIAO1 and MMS19, binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins (PubMed:23891004, PubMed:29848660).  As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD (PubMed:20797633).  Together with MMS19, facilitates the transfer of Fe-S clusters to the motor protein KIF4A, which ensures proper localization of KIF4A to mitotic machinery components to promote the progression of mitosis (PubMed:29848660).
What are the official names of this protein?
Cytosolic iron-sulfur assembly component 2B, MSS19-interacting protein of 18 kDa, Mitotic spindle-associated MMXD complex subunit MIP18, Protein FAM96B.
What is the protein family that this protein belongs to?
Belongs to the MIP18 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody. Note=In mitosis, localizes to the spindle during metaphase and the spindle midbody during telophase (PubMed:29848660). Co-localizes with KIF4A to the spindle midzone and midbody during telophase and cytokinesis (PubMed:29848660).
Protein: RL35_LIMF3
Sequence: MPKMKTKSAAAKRFKRTAKGGFKSGNSFTSHRFHGKTKKQRRQLRGLSMMDKSNVKRYKKMIPAK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: PLSX_PHOPR
Sequence: MTGLTVALDAMGGDFGPQVIVPAAVQALLQYPELKIKLYGDHSAITAQLSLLNQHSYSRISIIHSDLVIADETRPSHALRRSQGTSMRMALDAVSDGEADACVSAGNTGALMALSRYTLKQLPGVDRPALVSAIPTHGLNKTWLLDLGANVSCDADTLFQFAVMGSVLAEQSLTSKPRVALLNIGEEEIKGNDLVKRCAEMLSNSPDIHYIGYIEGDQLYAGKADVIVCDGFVGNVSLKTSEGVANLFINSFKQTISTNPMKRLLAKWLFRDLFVSLKKLNPDQYNGASLLGLRGIVVKSHGRADTAAFANAIGEAVHEVKRQIPTKISDRLEEVLLERHY
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: NFUA_SALDC
Sequence: MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYALQSQINPQLAGHGGRVSLMEITDEGYAILQFGGGCNGCSMVDVTLKEGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
What is the function of this protein?
Involved in iron-sulfur cluster biogenesis.  Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins.  Could also act as a scaffold/chaperone for damaged Fe/S proteins.
What are the official names of this protein?
Fe/S biogenesis protein NfuA.
What is the protein family that this protein belongs to?
Belongs to the NfuA family.
Protein: ARRC_PIG
Sequence: MSRVFKKTCSNGKLSIYLGKRDFVDHVDMVEPIDGVVLVDPEYLKGRKMFVMLTCAFRYGHDDLDVIGLTFRKDLYVQVQQVVPAEPTSPQVPLTVLQERLLHKLGDNAYPFNLQMVVNLPCSVTLQPGPDDTGKACGIDFEVKSFCAENLEEKVSKKDSVRLVIRKIQFAPVEPGPGPWAQTVRRFLLSAQPLQLQAWMDREVHYHGKPISVNVSINNSTNKVIKKIKISVDQITDVVLYSLDKYTKTVFIQEFTETIAANSTFSKSFEVTPLLADNCEKQGLALDGKLKHGDTNLASSTILRPGMDKELLGILVSYKVRVNLMVSCGGILGDLTASDVGVELPLILMHPKPSNEAASSEDIVIEEFARQEPGGREESQEALAAEGDEGS
What is the function of this protein?
May play a role in an as yet undefined retina-specific signal transduction.  Could bind to photoactivated-phosphorylated red/green opsins (By similarity).
What are the official names of this protein?
Arrestin-C, Cone arrestin, cArr, Retinal cone arrestin-3.
What is the protein family that this protein belongs to?
Belongs to the arrestin family.
What are the subcellular locations of this protein?
Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment.
Protein: RS9_CAMJ8
Sequence: MATTYATGKRKTAIAKVWVKPGSGKISVNGVDLNTWLGGHEAIKLKVVQPLLVTKQETSMDIKATTLGGGYSAQAEALRHGISRALAAMDADFRALLKPKGLLTRDSRTVERKKYGRRKARRSPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: ATPG_PSECP
Sequence: MGAQIRVYRQKISSTTSMRKIFKAMELIATSRIGKARARVAASLPYANAITRAVSAVASQSEIDHPLTTEPEQIRRAAVLVITSDRGLAGSYSASVLKQAEGLNELLHAEGKEVKTYLVGRKSQAYFDFRNREYARVWTGGTDAPEFGTAREIGAALLADFAADFEDGGVDEIHVVYTRFKSMVTQEPTVIRLLPLEVVEEEAASESDLLPLYEFEPETEQVLDALLPRYIESRLFAAMLQAAASELAARQRAMKSAGDNATDLIKKYTRLRNTARQAEITQELSEIVAGADALAS
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.