PharMolix/UniProtQA huggingface dataset:
Protein: NCAP_LYCVW
Sequence: MSLSKEVKSFQWTQALRRELQGFTSDVKAAVIKDATSLLNGLDFSEVSNVQRIMRKERRDDKDLQRLRSLNQTVHSLVDPKSTSKKNVLKVGRLSAEELMTLAADLEKLKAKIMRTERPQASGVYMGNLTAQQLDQRSQILQMVGMRRPQQGASGVVRVWDVKDSSLLNNQFGTMPSLTMACMAKQSQTPLNDVVQALTDLGLLYTVKYPNLSDLERLKDKHPVLGVITEQQSSINISGYNFSLGAAVKAGAALLHGGNMLESILIKPSNSEDLLKAVLGAKKKLNMFVSDQVGDRNPYENILYKVCLSGEGWPYIACRTSVVGRAWENTTIDLTNEKLVANSSRPVPGAAGPPQVGLSYSQTMLLKDLMGGIDPNAPTWIDIEGRFNDPVEIAIFQPQNGQFIHFYREPTDQKQFKQDSKYSHGMDLADLFNAQAGLTSSVIGALPQGMVLSCQGSDDIRKLLDSQNRRDIKLIDVEMTKEASREYEDKVWDKYGWLCKMHTGVVRDKKKKEITPHCALMDCIIFESASKARLPDLKTVHNILPHDLIFRGPNVVTL
What is the function of this protein?
Encapsidates the genome, protecting it from nucleases.  The encapsidated genomic RNA is termed the nucleocapsid (NC).  Serves as template for viral transcription and replication.  The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses.  Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation.  Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
What are the official names of this protein?
Nucleoprotein, Nucleocapsid protein, Protein N.
What is the protein family that this protein belongs to?
Belongs to the arenaviridae nucleocapsid protein family.
What are the subcellular locations of this protein?
Virion. Host cytoplasm.
Protein: CH602_MYCBO
Sequence: MAKTIAYDEEARRGLERGLNALADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPLGLKRGIEKAVEKVTETLLKGAKEVETKEQIAATAAISAGDQSIGDLIAEAMDKVGNEGVITVEESNTFGLQLELTEGMRFDKGYISGYFVTDPERQEAVLEDPYILLVSSKVSTVKDLLPLLEKVIGAGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLQDMAILTGGQVISEEVGLTLENADLSLLGKARKVVVTKDETTIVEGAGDTDAIAGRVAQIRQEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVTLLQAAPTLDELKLEGDEATGANIVKVALEAPLKQIAFNSGLEPGVVAEKVRNLPAGHGLNAQTGVYEDLLAAGVADPVKVTRSALQNAASIAGLFLTTEAVVADKPEKEKASVPGGGDMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL 2, 60 kDa chaperonin 2, 65 kDa antigen, Antigen A, Cell wall protein A, Chaperonin-60 2, Cpn60 2, Heat shock protein 65.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Secreted, capsule. Cell surface. Secreted, cell wall.
Protein: FSX1_UNCAX
Sequence: MRRAALILAFVLFIGLSSATVTSADSITYNSGTSEFFDGDVFAIEVTADQSTDEIDIYLGASELSEKTDGEVNQDLSIEFTHQDSKLKYSTSTSDELRDIVTLTTYYEDGFDTEQDAIDAIKSDCYDLNQNGNGSGRYSRYYSVTSPVYDYEIYCFQKNEKLATPAYIDNPDEIFTAKAELQAGDKTIQSATLSNGDAGDGTVTDLGDSKISWNGNLDLGASEPENSRVIALYSNDFENGWRIGNKQSYEDYKTFIGGGDAYDLLIDWQDGTYTASEVEDELVNTDANQAVEEASSSTTDLVNAKVKDSSLDTGSFVYDTPELLSYPSFTVYVDAGENGYIEVTKPTGDPDIISTSSTEIKEGDEGTVTATVENVGDGEGEFSGRLSSCGEGFSIVDDQNTKNVGAGESVTYSFDVAFSSVSSESKEISGSCTFEVNGVESSDSTSVSVTGIQQSECNPGDQRREKNENDRWEIYTCQDNGLTYEYDVTCAEDEKAVAQGDNQFSCEKQDDDSGGGDNTGSDSGLFSNLFGGSGSGDLLTQVHTALSILAGLVAGFFGYRGARWIHGETDIKGGFKLESRNVSRVKRGSPVAGIVGAVLGFVVGYGVASVFHPVVQIIVVLGIAVGLYYFR
What is the function of this protein?
Exhibits fusogenic activity (PubMed:35794124).  Mediates cell-cell fusion in mammalian cells when present in both cells (bilateral fusion) (PubMed:35794124).
What are the official names of this protein?
Fusexin 1, Fsx1.
What is the protein family that this protein belongs to?
Belongs to the HAP2/GCS1 family. Fusexin 1 subfamily.
Protein: Y2730_ACIET
Sequence: MPFDARTRPLTAPQARVLATLLEKSRTVPDSYPLTLNSLLAGCNQKSSRDPVMQLTESEVQQALDELRQQTLVLEIGGARVARWEHNFTRGVGVPDQSAALLGLLMLRGPQTAGELRINAERWHRFADISSVEAFLDELQSRSDDKGGPLVTLLPRAPGAREPRWAHLLCGPVDASPVQMASASPASRSEEDGALAQRVQALEDEVAALRATVQRLCEQLGVAEH
What are the official names of this protein?
UPF0502 protein Dtpsy_2730.
What is the protein family that this protein belongs to?
Belongs to the UPF0502 family.
Protein: 3SA8_NAJHA
Sequence: LKCHKLVPPFWKTCPEGKNLCYKMYMVSTLTVPVKRGCIDVCPKNSALVKYVCCNTNKCN
What is the function of this protein?
Shows cytolytic activity on many different cells by forming pore in lipid membranes.  In vivo, increases heart rate or kills the animal by cardiac arrest.  In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity.
What are the official names of this protein?
Cytotoxin 8, Toxin CM-7.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Type IA cytotoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane.
Protein: DPO3A_MYCPN
Sequence: MFVNLHTNSYYNFLNSTLSPQKLVDLAVQDQQVAVCLTDPNLFGATEFFLACQKAHIKPLIGLSVTVRHYEQNVNLLVIAQTNRGYQNLMCLALVKDQPDLQLEPFLDGNVVIICTQTELRLNTANPVYLAHGLSGRYPKIAVTQKPVKCQNTNKDLTLLLTLKQISQINSEHFQPLEWKLSRSLNEIQLDPPLLQQLRHQPFLSQKAAQQIFSEEELGNLQKLVEQSQWDLTKLKASSLQVSHNDAQMLSEQCQLALTEFLKLNPQLNKQLYEERLAKELEIINSLHFASYFLVVSDLVQFAHNNDILIGPGRGSAVGSLVAFLLKITQIDPVANNLIFERFISRHRQGLPDIDIDIMETKRDLVIDYVMQKYGREQCAQIVTFQKFKTRSALRDVGKVFNHIEGAEDLLGKLPKDKSLLELDVNGVTDPVLQLSLKSFRLLWEVAREIINFPRQPSIHASGVVIVTEPLITTIPLMVGNNNNYVTQVSMDWLEWYNLNKFDLLGLINLTMIHEVVQAVKPKEVSVQQFLQQIPLDDEATFTNLTNQATLGVFQLESFGMKKVLKQIKPHNLHDLAIVLALYRPGPQDNINTFIANRNLGFDTSDIDPRILPILKETYGVLIFQEQVINIAKTVANYSLETADSFRRAISKKNLQVIQDNMRSFYEGALANNFSLKAATTIFNYIQRFAGYGFNLSHALGYALLSYWTAWLKTHYFEQFNLWWLNHEQGKKEKQKQLLNEFISSGYEICPPLINKAKSDFSVQDKKLYLGFKLINGIGDKQAHALEHVQEVLKQNPNLSLIATVNLCLSKTVGGLELKDITLLQQAGCFNCFNYTVDFNLAKSFWVQSNHELFPKIPLDQPPVINWKSFGF
What is the function of this protein?
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria.  This DNA polymerase also exhibits 3' to 5' exonuclease activity.  The alpha chain is the DNA polymerase (By similarity).
What are the official names of this protein?
DNA polymerase III subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-C family. DnaE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_DAMPY
Sequence: MTNIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFLHVGRGLYYGSYTFLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPTGISSDADKIPFHPYYTIKDILGALLLILALMLLVLFAPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILVLMPLLHTSKQRSMMFRPISQCVFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLLILVVMPTASTIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y1380_NEIMF
Sequence: MFGKAGLGGLMKQAQQMQENMKKAQAKLAETEIEGEAGNGLVKITMTCAHEVRKIDISPDLIQEAADDKEMLEDLILAALKSARGKAEETANKTMGAFTQGLPPGVGDFFR
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein NMC1380.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS182_FRAAA
Sequence: MRKPKKKVCVFCKDKVEYIDFKDTSLLRKYISDRGKIRARRVSGNCSQHQRDVATAVKNSREMALLPYTASAR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: FETP_BURM7
Sequence: MARMIHCAKLGKEAEGLDFPPLPGELGKRLYESVSKQAWQDWLKQQTMLINENRLNMADPRARQYLMKQTEKYFFGEGADQASGYVPPAQG
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: PEX6_DICDI
Sequence: MIGLFKDEWFNISILNDNLFLKRYCYESNNNNNNNNTLYTIIVPFDKSINPSQFDPSTINDYFIFLYKNTKKINLNSINKLQYKSNKKEILVSFDITYIHNSNNNNNNNNNKLKSVLISNSCSKKLNLFNNDIVHLKPIKKKLTVLQRVVLLANDNESFIESSNPSESSSSTTTINSKYLVNEEFRNYLVENSILFQSPNNIVIENHQKHKSFSYKVLECFPLLQGTVSNSTTIIIISPDDKILNTLPSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKEEEVEEEEVEVEEEEKDNKLKLNNNLRLSNFIIHPIINISNNTTTKNEDIGDSNNLFHFTPSSKGILSNNKKFINISQLKSIPTEIDFEFDISKEYDYLVDCLVSLNTLKSLNLFNGSWIKIKNITNNNNNNNNKEYEIAIRIFSITSSLKLKDQVLYLPPISIFNLNIDYKNFLKLSNYEIISNQFELILLKSNKPNINNNNNNDSFPINYPTANRIKISRIKNQNSSGYKSYSHQLEKYFQKKRLLKQNDIIVISTKVNNEEELINSNNSNNNNNYNNNNNNNNNNNLVYFKVEIILCNQFENINGNQIYLIDKNTTSIIQEGSSNSMVPSKIESFYWRGGDQEESKDNSMVPLELIYENEFKTIVDLISPFLMGDKFSFDFNCTLLLNGPQGVGKRTLLNRVAKQMGIHVYEVDCYKLYDFVESKKDWNIRNVLEQASNSTPTLLILKNFEVLEQTAQSMQQEKKESNLSQTLINILKDINDSNTSNINSNKYPLIITVTVNSMDELSNKVRNWFKHEITLNSPDENQRFKILKYLTKNLPIDIGNTVSIKNLSIRTASFLNSNLRALIQRSSINALKRVLSIQQMMNDEIKPIEIYNCGFLVMGDDIQKSLSEMQEYQSSSIGAPKIPNVSWDDVGGLANVKSEIMDTIQLPLEHPHLFASGIGKRSGILLFGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEKNIREIFNKARQAKPCVIFFDELDSLAPSRGNGADSGGVMDRVVSQLLAELDGMQKSSDVFIIGATNRPDLLDSSLMRPGRLDRLLYLGISSEKENQFKILQALTRKFNLADDVDLRKVVENCPMNLTGADFYALASDAMSNAFHERITASINGEINEEEQNQKLIVYQNHFIKAVNSLVPSVSLDELEYYHKVQKQFSGNNKS
What is the function of this protein?
Component of the PEX1-PEX6 AAA ATPase complex, a protein dislocase complex that mediates the ATP-dependent extraction of the PEX5 receptor from peroxisomal membranes, an essential step for PEX5 recycling.  Specifically recognizes PEX5 monoubiquitinated at 'Cys-11', and pulls it out of the peroxisome lumen through the PEX2-PEX10-PEX12 retrotranslocation channel.  Extraction by the PEX1-PEX6 AAA ATPase complex is accompanied by unfolding of the TPR repeats and release of bound cargo from PEX5.
What are the official names of this protein?
Peroxisomal ATPase PEX6, Peroxin-6, Peroxisomal biogenesis factor 6.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
What are the subcellular locations of this protein?
Cytoplasm. Peroxisome membrane.
Protein: HEMA_I86A1
Sequence: QKLPGNDNSTATPCLGHHAVPNGTLVETITNDQIEVTNATELVQSSSTGRICDSPHRILDGKNCTLIDALLGDPHCDGFQNEKWDLFIERSKAFSNCYPYDVPDYASLRSLVASSGTLEFINEGFNWTGVTQSGGSYACKRGSVNSFFSRLNWLYESEYKYPALNVTMPNNGKFDKLYIWGVHHPSTEKEQTNLYVRASGRVTVSTKRSQQTVIPNIGSRPWVRGLSSRISIYWTIVKPGDILLINSTGNLIAPRGYFKIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNKITYGACPRYVKQNTLKLATGMRNVPEKQTRGIFGAIAGFIENGWEGMVDGWYGFRHQNSEGTGQAADLKSTQAAIDQINGKLNRLIEKTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFEKTRKQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLLCVVLLGFIMWACQKGNIRCNICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: DCUP_SULNB
Sequence: MSKIFVDACLGKETPYTPVWMMRQAGRYLPEYMKVRAEAGNFLNLCHDPEKACEVTLQPVDIVGVDAAILFSDILVIPDEMGMDLSFVKGEGPKFSDPIKTQADVDRLIGGEEAAGKLTYVYDTIKLIKERLAEDKALIGFTGAPWTLATYMIEGQGTKTYNICKKMMYSDPELLHNILAKVTEVVKYYMEKQIEAGIDVVQIFDSWASAIEPGKYDEFSWKYMVEIADYLKSKYPDTPIIMFPKGIPAFIERGLVYGNFDVFGVDWGTPMALAKEKLGDQYVLQGNMEPCRLYSKEATTECVEAIQKVMGGKRHIFNLGHGILPDVPVENAKHFVNECHRVSGKK
What is the function of this protein?
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
What are the official names of this protein?
Uroporphyrinogen decarboxylase, UPD, URO-D.
What is the protein family that this protein belongs to?
Belongs to the uroporphyrinogen decarboxylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ULAR_SHIBS
Sequence: MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSENSLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQLEAQGVSILRV
What is the function of this protein?
Represses ulaG and the ulaABCDEF operon.
What are the official names of this protein?
HTH-type transcriptional regulator UlaR.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXO_MYCTO
Sequence: MTINYQFGDVDAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQAAGNNMAQTDSAVGSSWA
What are the official names of this protein?
ESAT-6-like protein EsxO.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family. ESAT-6 subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Probably secreted via the ESX-5 / type VII secretion system (T7SS).
Protein: DSDX_ECOL6
Sequence: MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMMGMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSADVIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPPHPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLKVRDEKTLPSLGATLFTVLLPIALMLVKTIAELNMARESGLYTLLEFIGNPITATFIAVFVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVILSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTFLLSFII
What is the function of this protein?
Protein that allows transport of D-serine across the inner membrane, does not transport D-alanine nor probably glycine.  Is probably a H(+) symporter, as CCCP inhibits transport.  Transports D-serine more efficiently than CycA.
What are the official names of this protein?
D-serine transporter DsdX, D-serine-specific permease.
What is the protein family that this protein belongs to?
Belongs to the GntP permease family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: IDHP_PIG
Sequence: ARAAARHYADQRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVVDRAGTFKIVFTPKDGSSAKQWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTDFDKYKIWYEHRLIDDMVAQVLKSSGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIHGLSNVKLNEHFLNTSDFLDTIKSNLDRALGRQ
What is the function of this protein?
Plays a role in intermediary metabolism and energy production (PubMed:14512428).  It may tightly associate or interact with the pyruvate dehydrogenase complex (PubMed:14512428).
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], mitochondrial, IDH, ICD-M, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: MELC_BACSU
Sequence: MRAARTKSMRIITLLAAIVACAHFIPFYILLTTSLKAKGDYSSKWIFPADISFHNFSEAWERASLGNSFINTMIITGFSALLLIIFGSLAAYPLARRETKLNKAVFALLISIMIIPPLTSMVPLYRMVVDAGMVNTHAIAIFINTAAYMPLTVFLYSGFIRSTIPKELVEAARIDGAGMLKIFFTIVFPLLKPITATICIISCVFIWNDYQFAIFFLQDQKVQTLTVAMAGFFGENANNLHLVAAAALMAMLPMVVLFLALQKYFIAGLSSGAVKG
What is the function of this protein?
Part of the ABC transporter complex MelEDC-MsmX involved in melibiose, raffinose and stachyose import.  Probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Melibiose/raffinose/stachyose import permease protein MelC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPIA_SHEB8
Sequence: MTQDEMKKAAGWAALKYVEKDSIVGVGTGSTVNHFIDALATMKADIEGAVSSSEASTQKMKALGIPVYDLNSVDRLSVYVDGADEINDHMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVDILGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGVVTDNGNVILDVYNLKILNPKELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTAK
What is the function of this protein?
Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
What are the official names of this protein?
Ribose-5-phosphate isomerase A, Phosphoriboisomerase A, PRI.
What is the protein family that this protein belongs to?
Belongs to the ribose 5-phosphate isomerase family.
Protein: YEGS_ECOSM
Sequence: MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALGGVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALINDGLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQNFHIEILPAALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_SYNY3
Sequence: MPKYDSHLKCSFCGKSQEQVRKLIAGPGVYICDECVELCNDILDEELLDVPPASTGERDGTGQKQKKSGQPRRRLTLEELPKPTAIKQYLDEYVIGQDEAKKVLSVAVYNHYKRLNLLERNQEIDPGDAVELQKSNILLVGPTGSGKTLLAQTLAKILEVPFAVADATTLTEAGYVGEDVENILLRLLQVADLDVEEAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSNILFICGGAFVGLEKVIEQRFGKKSMGFVRPGEGPSKEKRTADVLRQAEPDDLVKFGLIPEFIGRIPVMACLNPLDEDALIAILTQPRNAIVKQYQTLLGMDHVELDFQPDAVRAIATEAHRRKTGARALRGIVEELMLDVMYELPSREDLTHCLITREMVEKRSTAELLLHPSSLPKPESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CAZ_DROME
Sequence: MERGGYGGGSGQGYNNFAVPPPNYQQMPNKTGNYNEPPPNYGKQGGGYDSGSGHRGSGGSGNGGGGGGSWNDRGGNSYGNGGASKDSYNKGHGGYSGGGGGGGGGGGGGSGGNDMITQEDTIFVSGMDPSTTEQDIETHFGAIGIIKKDKRTMKPKIWLYKNKETGASKGEATVTYDDTNAAQSAIEWFDGRDFNGNAIKVSLAQRQNNWNKGGGGGGGGGGRGGFGGRRGGGGGGGGGGGGGGRFDRGGGGGGGRYDRGGGGGGGGGGGNVQPRDGDWKCNSCNNTNFAWRNECNRCKTPKGDDEGSSGGGGGGGYGGGGGGGGYDRGNDRGSGGGGYHNRDRGGNSQGGGGGGGGGGGYSRFNDNNGGGRGGRGGGGGNRRDGGPMRNDGGMRSRPY
What is the function of this protein?
May participate in a function common to the expression of most genes transcribed by RNA polymerase II.
What are the official names of this protein?
RNA-binding protein cabeza, P19, Sarcoma-associated RNA-binding fly homolog.
What is the protein family that this protein belongs to?
Belongs to the RRM TET family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PUR1_STAAR
Sequence: MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIVVSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPLLYHFYDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKESLRKIKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQDIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKMLAQESPVKADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQGVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFPSFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVESFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHYFDSEGNLNV
What is the function of this protein?
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
What are the official names of this protein?
Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPATase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Protein: ECM14_ASPTN
Sequence: MRSLLSIILILVASAALIAAVPAGSSITPPPPIEPVQLLSSQPSDSKRPWIRLRDWIIESIWGIPKSRSPGFPSKDAAGRAPPSQVLARYGSDVVLRFQLRDQQEAEALAQATDILFLDVWASTSEFVDIRLAQEVIPSLLGLLPDSLRTAYTPLIDNLSEMIYTSYPTRRPVGLENQPGFSSSIRQSQQFGDLFFRDYQPLSVIVHWMRLMSSMFSSHVRLINVGVSYEGREIPALRLGTSGPNTQDTPRKTVLMVGGSHAREWISTSTVTYVAYQLIAKYGKSRAVTRLLEEFDWVFVPTLNPDGYVYTWESDRLWRKNRQPTSLRFCPGIDLDRAWSFEWDGERTRTNPCSENYAGDEPFEGLESAQLAQWALNETQHHNAEIVAFLDLHSYSQQILYPFSFSCSTMPPTLESLEEVAMGLAKTIRQTTQEVYDVTSACEGIVTAQEQKASKRFFPVGGSSGGSALDWFYHQLHTIYSYQIKLRDRGSYGFLLPSEHIVPTGKEMYNVALRLGQFLVGESAQDIDWSADLMDAPGTSDDGRETDVDLNRDGAGEEGVDSELDAVDEEWELIDWEDEHTYELRK
What is the function of this protein?
Inactive carboxypeptidase that may play a role in cell wall organization and biogenesis.
What are the official names of this protein?
Inactive metallocarboxypeptidase ecm14.
What is the protein family that this protein belongs to?
Belongs to the peptidase M14 family.
What are the subcellular locations of this protein?
Vacuole. Secreted.