PharMolix/UniProtQA huggingface dataset:
Protein: ISPF_ROSDO
Sequence: MDIRLGNGFDVHAFGPGDHVTLCGVKIPHGQGLVGHSDADVAMHTVTDAIYGALAMGDIGQHFPPSDPQWKGAASDIFLKHAVAQASEQGFEINNVDCTLICEFPKIGPHAQAMREAMARIMGMALSRISVKATTSERLGFTGRGEGIACIATAALVRA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: ISPE_ECO8A
Sequence: MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: LAAT1_MOUSE
Sequence: MVWRTLGASNFSTCPNGSVQWIWDVFGECAQDGWDEASVGLGLVSILCFAASTFPQYIKACKTGNMDQALSLWFLLGWIGGDSCNLIGSFLADQLPLQTYTAVYYVLADLMMLTLYFHYKFKKRPSPLSAPINSVLLFILGTVCITPLLSSTDPVAVPREGFRGRTLLSVEPGNKPFTKKEVIGFVIGSASSLLYLLSRLPQIRTNFIRQSTQGISYSLFALVMLGNTLYGLSVLLKNPEVGQSEGSYLLHHLPWLVGSLGVLLLDTIISIQFLVYRSHETAAASEREPLLPS
What is the function of this protein?
Amino acid transporter that specifically mediates the pH-dependent export of the cationic amino acids arginine, histidine and lysine from lysosomes.
What are the official names of this protein?
Lysosomal amino acid transporter 1 homolog, PQ-loop repeat-containing protein 2, Solute carrier family 66 member 1.
What is the protein family that this protein belongs to?
Belongs to the laat-1 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: PRVA_TRISE
Sequence: PMTKVLKADDINKAISAFKDPGTFDYKRFFHLVGLKGKTDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIGADEFAKMVAQA
What is the function of this protein?
In muscle, parvalbumin is thought to be involved in relaxation after contraction.  It binds two calcium ions.
What are the official names of this protein?
Parvalbumin alpha.
What is the protein family that this protein belongs to?
Belongs to the parvalbumin family.
Protein: ZAPB_SALHS
Sequence: MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLTQEVQSAQHQREELERENNSLKEQQSGWQERLQALLGRMEEV
What is the function of this protein?
Non-essential, abundant cell division factor that is required for proper Z-ring formation.  It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle.  Its recruitment to the Z-ring requires functional FtsA or ZipA.
What are the official names of this protein?
Cell division protein ZapB.
What is the protein family that this protein belongs to?
Belongs to the ZapB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to the septum at mid-cell, in a FtsZ-like pattern.
Protein: XYLB_ARTS7
Sequence: MTLVAGIDSSTQSCKVVIRDADTGVLIRSSRASHPDGTEVDPEFWFDALQEAIAQAGGLDDVAAISVGGQQHGMVALDATGAVIRPALLWNDNRSA
What is the function of this protein?
Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.
What are the official names of this protein?
Xylulose kinase, Xylulokinase.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: RPPH_SHELP
Sequence: MIDSDGFRANVGIIICNRFGQVMWARRFGQHSWQFPQGGVDEGESAEQAMYRELYEEVGLRPEHVQVLTSTRSWLRYRLPKRLIRQDSKPLCIGQKQKWFLLQLKSQESAIDLAASGHPEFDDWRWVSYWYPVRQVVSFKRDVYRKVMKEFAPTALPFQAQENTQGGRRRGRRR
What is the function of this protein?
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
What are the official names of this protein?
RNA pyrophosphohydrolase, (Di)nucleoside polyphosphate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. RppH subfamily.
Protein: YJIX_ECOL6
Sequence: MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSYEEFFRERQNARYGGDGKGGMRCC
What are the official names of this protein?
Uncharacterized protein YjiX.
What is the protein family that this protein belongs to?
To E.coli YbdD.
Protein: Y2132_NATPD
Sequence: MELTWYGHSTWHVSVGSTDLLIDPFFGNPKTDLEPSDLDSPDYVLLTHGHEDHVAHAGAFSDATLVATPELVGYAEDNFGFEDAVGGMGMNLGGSVECGDAWVTMTRADHSNGIETGYETSAGMPAGFVVSESEPQRASDAANTAFYHAGDTSLMVEMREVIGPYLEPDFAALPAGDHFTMGPEQAAIAADWLGADYAAPMHYDTFPPIEIDTDEFVDALNATGADAEAVVLDGDESFTLG
What are the official names of this protein?
UPF0173 metal-dependent hydrolase NP_2132A.
What is the protein family that this protein belongs to?
Belongs to the UPF0173 family.
Protein: TTLL5_HUMAN
Sequence: MPIVMARDLEETASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHADAILTKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESSRRNPFQKPQRCRPLSASDAEMKNLVGSAREKGPGKLGGSVLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRMTADGAPELKIESLNSKAKLHAALYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGFLRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLKRASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVNMENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSSSGPTATLQKIPNTHLSSVTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSAAHIYSQKLSRPSSAKAGSCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQVTNLNLATGIINRSSASAPPTLRPIISPSGPTWSTQSDPQAPENHSSSPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYHPTAGSYQLQFALQQLEQQKLQSRQLLDQSRARHQAIFGSQTLPNSNLWTMNNGAGCRISSATASGQKPTTLPQKVVPPPSSCASLVPKPPPNHEQVLRRATSQKASKGSSAEGQLNGLQSSLNPAAFVPITSSTDPAHTKI
What is the function of this protein?
Polyglutamylase which modifies tubulin, generating polyglutamate side chains on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of tubulin.  Preferentially mediates ATP-dependent initiation step of the polyglutamylation reaction over the elongation step.  Preferentially modifies the alpha-tubulin tail over a beta-tail (By similarity).  Required for CCSAP localization to both polyglutamylated spindle and cilia microtubules (PubMed:22493317).  Increases the effects of transcriptional coactivator NCOA2/TIF2 in glucocorticoid receptor-mediated repression and induction and in androgen receptor-mediated induction (PubMed:17116691).
What are the official names of this protein?
Tubulin polyglutamylase TTLL5, SRC1 and TIF2-associated modulatory protein, STAMP protein, Tubulin--tyrosine ligase-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the tubulin--tyrosine ligase family.
What are the subcellular locations of this protein?
Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Nucleus. Cytoplasm. Note=Localized to the base of the connecting cilium between the basal body and the adjacent daughter centriole of the cilium. In osteosarcoma cells, found in both cytoplasm and nucleus in the absence of steroid but located exclusively in the nucleus in the presence of steroid.
Protein: Y1459_SYNY3
Sequence: MNFLLTNDDGIDAPGIEALYEALGKRGVWVAPKNQHSGCGHKVTTDQAIAVEQRGKNRYAVDGTPADCTRLGVVHFYPEVDWVIAGINAGGNMGIDSYLSGTVAAVREAAILGHKAIAISHWINKPRTINWAWASHWANAVFNTLWQQDLPPQHFWNVNLPHWQSGDPEPEVIFCEPSRDPLPVAFTIEGSNFFYRGEYSQRPRQPGSDIDVCFSGNIAITQLRV
What is the function of this protein?
Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.
What are the official names of this protein?
Putative 5'-nucleotidase alr3139, Nucleoside 5'-monophosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the SurE nucleotidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCH1_DEHMC
Sequence: MFDEQAIKQSVQNILVAIGEDPDREGLKETPRRVAQMYTELFSGMNQDPAEVLRVGYELGHREMVIIKDIPFYSMCEHHLLPFSGVVHIGYIPNIDGRVVGISKLARVVEIYAKRPQIQERMATQIADAIMDGLKCDGVAVVIEAEHMCMVMRGIKKPGSRVITSALRGSFHKSPAARAEFLSLIQHKG
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: CBPA_ECOSM
Sequence: MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFSRQFQHGDGQSFNAEDFDDIFSSIFGQHARQSHQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTLKVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFEPRKDWGKA
What is the function of this protein?
DNA-binding protein that preferentially recognizes a curved DNA sequence.  It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock.  Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK.  Its activity is inhibited by the binding of CbpM.
What are the official names of this protein?
Curved DNA-binding protein.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: PE2R3_MOUSE
Sequence: MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
What is the function of this protein?
Receptor for prostaglandin E2 (PGE2); ligand binding can activate several distinct signaling cascades, resulting in activation or inhibition of adenylate cyclase.
What are the official names of this protein?
Prostaglandin E2 receptor EP3 subtype, PGE receptor EP3 subtype, PGE2 receptor EP3 subtype, Prostanoid EP3 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ASF1_DICDI
Sequence: MSHIRLTQVLIHNNPSSFNSPFIFDISFECVSPIKEDLEWKVIYVGSADNEKNDQVLDSILLGPVAVGQNQFVFEVDPPDANKIPKDDLLGVTVVFLICAYKGEDFIRVGYYVNNDYFEQELKDNPPETPDLSKIQRNVMDDKPVVTGFPIQWN
What is the function of this protein?
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.  Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly (By similarity).
What are the official names of this protein?
Histone chaperone asf1, Anti-silencing function protein 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the ASF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CRUM3_CANLF
Sequence: MASPGLGLLLALGLPLLPARWGRAWGQTLDPHVNENGTITPSAPGSGSNGALSQEAITAIIVVFSLLAAVLLAVGLVLLLRKLREKRQTQGTYRPSSEEQFNHAAEARAPQDSKETVRGCLPI
What is the function of this protein?
Involved in the establishment of cell polarity in mammalian epithelial cells (By similarity).  Regulates the morphogenesis of tight junctions (By similarity).  Involved in promoting phosphorylation and cytoplasmic retention of transcriptional coactivators YAP1 and WWTR1/TAZ which leads to suppression of TGFB1-dependent transcription of target genes such as CCN2/CTGF, SERPINE1/PAI1, SNAI1/SNAIL1 and SMAD7 (By similarity).
What are the official names of this protein?
Protein crumbs homolog 3.
What are the subcellular locations of this protein?
Apical cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Note=Localizes primarily to the apical membrane with a small fraction in the upper part of tight junctions of epithelial cells.
Protein: ANDR_LITCT
Sequence: MEVHIGLGGVYKQPPGKMIRGAFENLFLSVREALQGERRSAASLDTSSPISACVHPHPTWNEPSTWTEVRGTPWREPQGAQPDPPPCSPRSQAPQFTLSSCTTELKEILGEQGGMPEEGNSESASKEGYPESISDSAKEICKAVSVSLGLSMEALEHLSAAGEWQRGDCMFAGPPHHTMGAQTCQVAEEDKSDTSFSQYREGAFRRAGQSTYSAGKAPEDGSSLPTEDKEQPCTDMALSEPGSLRSRGMEVMPSLTLYKPTAFMEDASAYPGRDYYSFQMALAPHGRIKVESPIEFAGSAWGGPSRYSEFPGFSHCGPSANWHSLFEEGQATASYTDSSLYSYPRSHVPAGPDGEFSAEAWYPATAMLGRVHMAVPMRPRMTHGWTATLGIRRRLGWTGVESTFYPIDYYFPPQKPCLSCEDEASGCHYEALTCGSCKVFFKRAAEGNQKYLCASRNDCTIDKFRRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKAQEELEGSPGQSEGREMPPNMSIPQLEGYSCQPIFLNVLEAIEPMVVCSGHDNNQPDSFALLLSSLNELGERQLVHVVKWAKALPGFRNLHVNDQMTVIQYSWMGLMIFAMGWRSFKNVNSRMLYFAPDLVFNEYRMHKSRMYSQCVRMRHLSQEFGWLQVTPEEFLCDEGPSALSIIPVEGLKDQKCFDELRMNYIKELDRVISCKRNNPASSSPRFFNLPKLLGSVQPIDVNLVQFTFGLFGKAQMVSVDFPEMMSEIISVQVPKILSGRVKPLYFHSS
What is the function of this protein?
Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.  Transcription factor activity is modulated by bound coactivator and corepressor proteins.
What are the official names of this protein?
Androgen receptor, bfAR, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR3 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: NIKO_RHOCB
Sequence: MTPAFELQGVQFAYKGVPALNGLDLTLPLGRRTALLGANGSGKSTLLRLLDGLQFPAAGRISAFGTPLTEAMFTDEAAAIAFRRRVGFVFQNPEVQLFCPSVFDELAFGPLQLHWPKERIRARVARAIAQFGLGPLAGRPPHRLSGGEKKRVALASVLILDPEVLLLDEPTAALDPQATDDIAALLETEFGARNPGRTLIFSSHDLDLVARIADHVVVLEAGKVAAAGPAAEVLARTALLRRARLLPGFDGTAP
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex NikMNQO involved in nickel import.  The complex confers nickel uptake upon expression in E. coli; can also transport cobalt with a very low affinity.  Presumably responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikO, Energy-coupling factor transporter ATP-binding protein NikO, ECF transporter A component NikO.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RS16_YERP3
Sequence: MVTIRLARGGAKKRPFYQVVVTDSRNARDGRFIERVGFFNPIASGQAEALRLDLDRIEHWIGLGATVSDRVSVLIKDAKKAA
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: TRI52_HUMAN
Sequence: MAGYATTPSPMQTLQEEAVCAICLDYFKDPVSISCGHNFCRGCVTQLWSKEDEEDQNEEEDEWEEEEDEEAVGAMDGWDGSIREVLYRGNADEELFQDQDDDELWLGDSGITNWDNVDYMWDEEEEEEEEDQDYYLGGLRPDLRIDVYREEEILEAYDEDEDEELYPDIHPPPSLPLPGQFTCPQCRKSFTRRSFRPNLQLANMVQIIRQMCPTPYRGNRSNDQGMCFKHQEALKLFCEVDKEAICVVCRESRSHKQHSVLPLEEVVQEYQEIKLETTLVGILQIEQESIHSKAYNQ
What is the function of this protein?
(Microbial infection) Exhibits antiviral activity against Japanese encephalitis virus (JEV).  Ubiquitinates the viral non-structural protein 2 (NS2A) and targets it for proteasome-mediated degradation.
What are the official names of this protein?
E3 ubiquitin-protein ligase TRIM52, RING finger protein 102, Tripartite motif-containing protein 52.
What is the protein family that this protein belongs to?
Belongs to the TRIM/RBCC family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytosol. Nucleus.
Protein: QUEF_BACC7
Sequence: MAGRLDEDLKDVTLLGNQNTKYLFEYSPEILEVFDNNHPNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPEQRMVESKSLKLYLFSFRNHGDFHEDCMNVIMNDLIKLMDPRYIEVWGKFTPRGGISIDPYCNYGRPGTKYEQMADYRMMNHDLYPETIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_RHIME
Sequence: MRDTSPFYITTAISYPNGKPHIGHAYELIATDAMARFQRLDGREVFFLTGTDEHGQKMQQTAKKEGISPQELAARNSAEFQNMARLLNASNDDFIRTTEQRHHEASQAIWMRMGEAGDLYKDSYAGWYSVRDEAYYQENETELRGDGVRYGPQGTPVEWVEEESYFFRLSAYQDKLLKHYEENPDFIGPAERRNEVISFVKSGLKDLSVSRTTFDWGIKVPNDPSHVMYVWVDALTNYVTATGCLTDPTGPRAKFWPANIHVIGKDIIRFHAVYWPAFLMSAGLPLPKRVFAHGFLLNKGEKMSKSLGNVVDPFNLVEHFGLDQIRYFFLREVSFGQDGSYSEEGIATRINSDLANGIGNLASRSLSMIVKNCDGQVPLCGPLTDEDKAMLAAADSLIGTAREEMGKQLIHRALAAIIAVVSETDRYFAGQEPWALKKTDPSRMATVLYVTAEVVRQVAILLQPFMPESAGKLLDLVAVPTDRRDFAHLGEAGRLVSGTPLEAPKPVFPRYVAPEA
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLA0_MAIZE
Sequence: MAIKRTKAEKKIAYDKKLCSLLDEYTKVLIALADNVGSKQLQDIRRGLRGDSVVLMGKNTLIRRCIKVYAEKTGNHTFDPLMDLLVGNVGLIFTKGDLKEVREEVAKYKVGAPARVGLVAPVDVVVPPGNTGLDPSQTSFFQVLNIPTKINKGTVEIITPVELIKKGEKVGSSESALLAKLGIRPFSYGLQVTSVYEDGSVFSPEVLDLSEEDLIEKFATGVSMVASLSLAISYPTLAAVPHMFINGYKNVLAVAVETDYSYPHADKIKEYLKDPSKFAVAAPVAAGDSGASAAPKEEEKAAEPEEESDEEMGFSLFDD
What is the function of this protein?
Ribosomal protein P0 is the functional equivalent of E. coli protein L10.
What are the official names of this protein?
60S acidic ribosomal protein P0.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: URE1_BURCJ
Sequence: MTLRLSRRAYAEMFGPTTGDRVRLADTELLIEIERDFTTYGEEVKFGGGKVIRDGMGQSQRVAADVPDTVITNAVILDHWGIVKADIAIKHGRIAAIGKAGNPDIQPGVTIAIGAATEVIAGEGLIVTAGGIDTHIHFISPQQIDEALASGVTTMLGGGTGPATGTNATTCTPGPWHMERMLQAADGWPINLGFLGKGNASLPQPLVEQIAAGAIGLKLHEDWGTTPAAIDNCLSVADDTDTQVAIHTDTLNEAGFVESTVAAFKGRTIHTYHTEGAGGGHAPDILKVCGEMNVLPSSTNPTRPYTINTLDEHLDMLMVCHHLDPSIAEDLAFAESRIRRETIAAEDILHDLGALSMLSSDSQAMGRVGEVIIRTWQTAHKMKVQRGALPEDTARNDNFRAKRYVAKYTINPALTHGIAHEVGSIEPGKWADLVLWEPAFFGIKPSMILKGGMIALAQMGDPNASIPTPQPVHYREMFATRGGALARTSLTFVSQMAADAGIAERYGLAKRIVPVRNCRNVTKADMIHNAWRPSISVDPETYDVIADGQLLTCEPATVLPMAQRYFLF
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEXA_ANOGA
Sequence: MKLLILAVAISLAVLASGSYVPSTKFEAKYADKEFLFKQKFFFEVLRNIHLPLKYDEYIPYTKTWVSDETKYNDFAQVAEFFDYYKTGAFLEKGELFSIYNEQYLRQTYAVFTFLYNSADWDTYYKNMIWARDNINEGMFIYVLHLTVMHRPDLQGIVLPAIYEIYPYYFFNTDVIRTINYKKLYDPKFGFYGNGKYNVVYANYTATYPMDYYNNFYTEEYLNYYTEDIGLNACYYYFMMDYSFLLGGDKFGLIKDRRGELYWYMHQMLLARYNLERMSNYMGTVKPLVWRFPLKTGYFSLLSYWNGVPFKSRDYNYMISDESYFKLDWINAWEAKIRKIIEDGFFVKEDGTRINLRLPESVEFFGNLLNSNVDSVDANYVGYIEVFSRLLLSGNDFNAYKVWPSALMQFETSLRDPVFYQLYERFMDLYYYFKRFLPSYTYEELNFNGVVIKDVTFDKLMTYFDYFDSDVSNVLPMQSTDKYFDYAVFARQRRLNHKPFSYTMNVMSDYTGKAIIRAFVGPKFDRFFDLQFYKKYFFEIDQYLVDFTAGKNTFVRNSRDFYWSVKDRTMYTDLYKKIMLGYNGQEKFALDMSEAHCGFPDRLILPKGWTSGMPMQFYFIITPYTAKTYEQGYQYDKTFTCGVESGMRFYDSLPFGYPFDRVINFNYFYTKNMYFKDVFIFHTEEMKMNQRY
What is the function of this protein?
Larval storage protein (LSP) which may serve as a store of amino acids for synthesis of adult proteins.
What are the official names of this protein?
Hexamerin-1.1, HEX-1.1, AgHex-1.1, AgHexA.
What is the protein family that this protein belongs to?
Belongs to the hemocyanin family.
What are the subcellular locations of this protein?
Secreted, extracellular space. Note=Minor constituent of late larval hemolymph.
Protein: DAPF_RUTMC
Sequence: MLINFVKMHGLGNDFMMVDNLAGDITFNAEQIANLANRHLGIGFDQLLLVETSNTKNVDFRYVIYNADGLEVEQCGNGARCFAFFVSKKGLSNNNPIVVETRSGIINLYLNDDNTVRVDMGKPSFNPADILLLVPQQSTYYQIEGFDLGAVSIGNPHCVMLVEDVNTVDVSSIALRIQQSELLPNQANIGFMQILNTHEINLRVYERGSGETLACGSGACAAVVYGVEQGLLKENVVAHLNGGDTLIEYIQGGHVFLSGPVQFVFEGKVEI
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_RHILO
Sequence: MSAPRVSFVSLGCPKALVDSERIITRLRAEGYEIARKHDGADLVVVNTCGFLDSARDESLNAIGSALSENGRVIVTGCLGAEPDVIREKHPNVLAITGPQAYESVMAAVHEAAPPSHDPYIDLLPPQGVKLTPRHYAYLKISEGCNNRCTFCIIPALRGDLVSRPAADVLREAEKLAKAGVKELLVISQDTSAYGIDIKYQTSMFGDREVRAKFLDLSEELGKLGIWVRMHYVYPYPHVADVIPLMAEGKILPYLDIPFQHASPQVLKNMRRPAHGEKTLERIRGWRDVCPDLAIRSTFIVGFPGETDEDFEMLLDWLDEAKIDRAGCFKYEPVKGARSNDLGLEQVPQDVKEARWHRFMQRQQKISATQLAKKVGKRLPVLIDEAHGTSAKGRTKYDAPEIDGSVHIQSRRPMRAGDIVTVKIERADAYDLYGSAV
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_NAUPA
Sequence: MIAALRGNIFEKDGGKILLDVNNVIYELNVSMITFSSVNDKGLFYITEIIKENEYTLYGFADKNEKKLFDSLIKLNGVGPKVALAICSTYTPQTFMDIIANHDINALKKIPGIGPKSAKRILMEMGEFEVVFEEQNPVFNQALSALESLGFNKNDIVKALNGIKSDNLEETIKLALKKLSKDIK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.