PharMolix/UniProtQA huggingface dataset:
Protein: QUEC_PSEA6
Sequence: MVQKVVVIFSGGMDSFTVLNMAVKEGYEVHALSFNYGQRHSKELDYASRACITLGVAHKIIDISAINELIGGSSLTSDVDIPEGHYAEESMKSTVVPNRNMILLSMAVGYAVSLDANKVYYGAHSGDHDIYPDCRPEFVERMNDVCAIANYEKVEIVSPFLYQSKIDILTAGLNMGLDYNLTWTCYNGREKACGKCGACQERLEAFDKNNAQDPLEYE
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: DJLA_ALIF1
Sequence: MQIFGKILGGFFGFLFGGFFGAALGIFIGHQFDKAKRMANSGFTFQTGGASQTQRQAEFFHAAYAVMGHVAKAKGQVTREEIQLASMMMDRMNLSDEQKREAQEAFREGKESDFPLRETLRNIRSITGGRYDLLQFFLELQIAAAIADGDIHPSERDVLHIVAEELGFSAEQLEKRLRMQEAAFRFQQGGGFSGHQSGGSHQQGQWQQASSASQLKDAYNLLGISEDADPKTIKRAHRKLMNEHHPDKLVAKGLPPEMMNMAKEKAQEIQAAYDLIKKEKGIK
What is the function of this protein?
Regulatory DnaK co-chaperone.  Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway.  The colanic acid capsule may help the bacterium survive conditions outside the host.
What are the official names of this protein?
Co-chaperone protein DjlA.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type III membrane protein.
Protein: ACKA_DEIDV
Sequence: MLTLVLNCGSSSVKFALLDLSANLTLLSGLAERLGSTGAVATLSRGENRRSVPVPDGSYAGAFEVVRAELGALGVREQVRAVGHRVVHGGERFSAPALIDAKVMAAIRACVPLAPLHNPANIAGIEAAQEAFGQLPHVAVFDTAFHQTMPDVAFRYAVPESWYAQHGVRRYGFHGTSHAYVAAEAARMLGMPLDALNLVTAHLGNGCSVAAVQGGRSIDTSMGLTPLEGLIMGTRSGDVDPGLHEFMARQAGLSLTQVTAALNKESGLSGLSGGLGSDMRELEAAAGRGHTGARLAVAAFVYRLAKGVAGMAVALGHLDALVFTGGIGENSATIRAATLERLGVLGFRLDQQANAQAVRGQPGLISAAGSVPALVVNTNEELSIARQTRQVLAAQTGDQA
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HORM1_XENLA
Sequence: MATAQMHRNKVNSVALPSRVATETQSLILVKRLLAVSVSCITYLRGLFPEYAYGTRYLDDICVKILREDKSCPGSTQLVKWMLGCYDALQKKYLRMVMLAIYTDPEDPQTVTECYQFKFKYTASGPVMDFVSNNSNSVSTCSDAKKTSILLIRKLYILMQNLGPLPNDVCLTMKLFYYDEVTPADYQPPGFKEGTCEGLMFEGEPMYLNVGEVATPFHVLKVKVTTEKERMENIEKSIFKKQASKQPQTDEEKPDLSINDDLAQDNNGDRKRDDIETLKVEDLNLTCQEDGNLQSDDSQNSALADSQEKTSQAAPPAFGRKTRSGRIFQKPDLELKNQKESARASKGNQQARKPEKRSQSFEITGSQEDPAVAKRRKFSEPRTPLN
What is the function of this protein?
Plays a key role in meiotic progression by ensuring that sufficient numbers of processed DNA double-strand breaks (DSBs) are available for successful homology search, promoting synaptonemal-complex formation independently and playing key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint.
What are the official names of this protein?
HORMA domain-containing protein 1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis.
Protein: PP4R1_MOUSE
Sequence: MADLSLLQEDLPEDADGLDVDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENVFNRQMVARSLLDTLREVCDDERDCIAVLERISRLADDSEPTVRAELMEQVPHIALFCQENRPSIPYAFSKYLLPIVVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIDLTAPDSNDDVKTEAVAIMCKMAPMVGKDITERLILPRFCEMCCDCRMFHVRKVCAANFGDICSVVGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSCATCQEIRRTKLSALFINLISDPSRWVRQAAFQSLGPFISTFANPSSSGQCFKDESKSSEDSSAEDKDRMRDNDVVEEEHRRPEDAPSDLSAPHSSARLESLEGCAAKTPGHSAGDVPAPVDSSLLCTLSSESPQEAASNDENGRKPDTNSKSASRPDAGTSSPEATPLDQDMFNSFHFWRTPLPKIDLDKELQQDPEERLSPERTGDVPAAPLPGPPNITMATRKELEEMIENLEPHMDDPDVKAQVDVLSAALRASSLDAHEETGGVEQRSELQDEVCVSELPDCNISHDTCVPLISAAEENAEATPDYVHGGADVSPGDGFSPDEDRRPKVQDVVPQALLDQYLSMTDPSRAQTVDTEIAKHCAYSLPGVALTLGRQNWHCLRETYETLASDMQWKVRRTLAFSIHELAVILGDQLTAADLVPIFNGFLKDLDEVRIGVLKHLHDFLKLLHIDKRREYLYQLQEFLVTDNSRNWRFRAELAEQLILLLELYSPRDVYDYLRPIALNLCADKVSSVRWISYKLVSEMVKKLHTATPPTFGVDLINELVENFGRCPKWSGRQAFVFVCQTVIEDDCLPMDQFAVHLMPHLLTLANDRVPNVRVLLAKTLRQTLLEKEYFLASASCHQEAVEQTIMALQMDRDSDVKYFASIHPSSTKLSEDAMSTASSTY
What is the function of this protein?
Regulatory subunit of serine/threonine-protein phosphatase 4.  May play a role in regulation of cell division in renal glomeruli.  The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3 (By similarity).
What are the official names of this protein?
Serine/threonine-protein phosphatase 4 regulatory subunit 1.
Protein: R37A2_ARATH
Sequence: MAKRTKKVGIVGKYGTRYGASIRKQIKKMEVSQHSKYFCEFCGKYGVKRKAVGIWGCKDCGKVKAGGAYTMNTASAVTVRSTIRRLREQIEG
What are the official names of this protein?
60S ribosomal protein L37a-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL43 family.
Protein: VKT4_CYRSC
Sequence: MGIARILSAVLFLSVLFVVTFPALLLADHHDGRIDTCRLPSDRGRCKASFERWYFNGRTCAKFIYGGCGGNGNKFPTEKACMKRCAKA
What is the function of this protein?
Toxin that shows weak activity against voltage-gated potassium channels (Kv), and no activity against serine proteases (PubMed:24418069).  The recombinant toxin shows a weak inhibition on Kv1. 1/KCNA1 (59. 2% inhibition at 10 uM) (PubMed:24418069).
What are the official names of this protein?
Kunitz-type kappaPI-theraphotoxin-Hs1e, KappaPI-TRTX-Hs1e, Huwentoxin HW11c4, Kunitz-type serine protease inhibitor HWTX-XI-IS4.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 02 (native) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: Y3657_BACCQ
Sequence: MAMRFLNIGYGNIVSAHRIIAIVSPESAPIKRTVQEAREHNALLDATYGRKTRAVIVMDDGHVVLSPIQPETIAHRLNNKEELSEEG
What are the official names of this protein?
Putative regulatory protein BCQ_3657.
What is the protein family that this protein belongs to?
Belongs to the RemA family.
Protein: FK104_ARATH
Sequence: MVTFWAETAASAATTSKGEPPSKKRKTNPSPPPSLLSLPDVLILNCLSRIPKSYYPKLSIVSKTFRDLIISIDLNHARFHHKTQEHFFHVCLKLPDRPLPSWYTLWIKPQGFDDKEEEKKKKKKSTLVQVPSSYASQTPLLVVGIDSDVYAFKQCYPPSRVMFVRNKECVIWRNAPDMTVARANPVAYVFDRKIYVMGGCAETESANWGEVFDPKTQTWEPLPVPSPELRFSSMIRKIEMIQGKFYVRSNDSKDSVYDPIREKWNVAAKPQLNDSRCSVGNVWYSCRPNSFLWFDNEIKNWRLIKGLSSLNHSCRSGLIETVCYDGNLLLLWDKPTKPRRRVCEDKYICCALISFNKRKNGQVWGKVEWSNVVLTVPSSYRFLRSTVIRT
What are the official names of this protein?
F-box/kelch-repeat protein At4g39753.
Protein: XDH1_ARATH
Sequence: MGSLKKDGEIGDEFTEALLYVNGVRRVLPDGLAHMTLLEYLRDLGLTGTKLGCGEGGCGACTVMVSSYDRKSKTSVHYAVNACLAPLYSVEGMHVISIEGLGHRKLGLHPVQESLASSHGSQCGFCTPGFIMSMYSLLRSSKNSPSEEEIEECLAGNLCRCTGYRPIVDAFRVFAKSDDALYCGVSSLSLQDGSTICPSTGKPCSCGSKTTNEVASCNEDRFQSISYSDIDGAKYTDKELIFPPELLLRKLTPLKLRGNGGITWYRPVCLQNLLELKANYPDAKLLVGNTEVGIEMRLKRLQYQVLISVAQVPELNALNVNDNGIEVGSALRLSELLRLFRKIVKERPAHETSACKAFIEQLKWFAGTQIRNVACIGGNICTASPISDLNPLWMASRAEFRITNCNGDVRSIPAKDFFLGYRKVDMGSNEILLSVFLPWTRPLEYVKEFKQAHRRDDDIAIVNGGMRVFLEDKGQQLFVSDASIAYGGVAPLSLCARKTEEFLIGKNWNKDLLQDALKVIQSDVVIKEDAPGGMVEFRKSLTLSFFFKFFLWVSHNVNNANSAIETFPPSHMSAVQPVPRLSRIGKQDYETVKQGTSVGSSEVHLSARMQVTGEAEYTDDTPVPPNTLHAAFVLSKVPHARILSIDDSAAKSSSGFVGLFLAKDIPGDNMIGPIVPDEELFATDVVTCVGQVIGVVVADTHENAKTAAGKVDVRYEELPAILSIKEAINAKSFHPNTEKRLRKGDVELCFQSGQCDRVIEGEVQMGGQEHFYLEPNGSLVWTVDGGSEVHMISSTQAPQKHQKYVSHVLGLPMSKVVCKTKRIGGGFGGKETRSAFIAAAASVPSYLLNRPVKLILDRDVDMMITGHRHSFLGKYKVGFTNEGKILALDLEIYNNGGNSLDLSLSVLERAMFHSDNVYEIPHVRIVGNVCFTNFPSNTAFRGFGGPQGMLITENWIQRIAAELNKSPEEIKEMNFQVEGSVTHYCQTLQHCTLHQLWKELKVSCNFLKARREADEFNSHNRWKKRGVAMVPTKFGISFTTKFMNQAGALVHVYTDGTVLVTHGGVEMGQGLHTKVAQVAASAFNIPLSSVFVSETSTDKVPNASPTAASASSDMYGAAVLDACEQIIARMEPVASKHNFNTFTELVSACYFQRIDLSAHGFHIVPDLGFDWISGKGNAFRYYTYGAAFAEVEIDTLTGDFHTRAADIMLDLGYSLNPAIDVGQIEGAFVQGLGWVALEELKWGDAAHKWIKPGSLLTCGPGNYKIPSINDMPFNLNVSLLKGNPNTKAIHSSKAVGEPPFFLASSVFFAIKEAIKAARTEVGLTDWFPLESPATPERIRMACFDEFSAPFVNSDFYPNLSV
What is the function of this protein?
Key enzyme involved in purine catabolism.  Catalyzes the oxidation of hypoxanthine to xanthine and the oxidation of xanthine to urate.  Regulates the level of ureides and plays an important role during plant growth and development, senescence and response to stresses.  Possesses NADH oxidase activity and may contribute to the generation of superoxide anions in planta.
What are the official names of this protein?
Xanthine dehydrogenase 1, AtXDH1.
What is the protein family that this protein belongs to?
Belongs to the xanthine dehydrogenase family.
Protein: EFTU_RICCK
Sequence: MAKAKFERTKPHVNIGTIGHVDHGKTSLTAAITIVLAKTGGAQATAYDQIDAAPEEKERGITISTAHVEYETKNRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLAKQVGVPAMVVFLNKVDMVDDPDLLELVEMEVRELLSKYGFPGDEIPIIKGSALQALEGKPEGEKAINELMDAVDSYIPQPVRATDKPFLMPIEDVFSISGRGTVVTGRVESGIIKVGEEIEIVGLKDTQKTTCTGVEMFRKLLDEGQAGDNIGVLLRGTKREEVERGQVLAKPGSIKPHDKFEAEVYVLSKEEGGRHTPFTNDYRPQFYFRTTDVTGTIKLPADKQMVMPGDNATFTVELIKPIAMQEGLKFSIREGGRTVGAGVVTKINN
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBK59_ARATH
Sequence: MMISDLPHDLESEILSRVPAKSLAKWKTTCKRWYALFRDPSFVKKNFDKAGGREMIVLMNSRVYSNSVNLQGINNRFDPSMEVTGKLIKLNDSKGVDISAIFHCDGLILCTTTESTGLVVWNPCTGEIRCIKPRIFYRCNDRYALGYGNSKSSCHSYKILRSCCYYVDQNLSLMAAEFEIYDFSTDSWRDLGDITRDMIVYSSGVSLKGNTYWVSGSKEKGFFMRYFDFSKEVFGRLPLPYQSFNANHTAALSAVGNEKIAVLQQKILAMSDEMRIWVTNKIDEAKDLSWSNFLLTVDYGKFNLPCLVNVTSFLLDEENKVAVCSDVDTKDGLRSRIYIVGKDFYKEVFKDTRGSDNNWPLLLCYVPSLVSIQENIPNKAEENEIKGG
What are the official names of this protein?
F-box/kelch-repeat protein At3g17530.
Protein: H4_EIMTE
Sequence: MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEEIRGVLKVFLENIIKDSVTYTEHARRKTVTAMDIVYSLKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: NDAD_ALCXX
Sequence: MSQSDSQPFDLLLAGGTLIDGSNTPGRRADLGVRGDRIAAIGDLSDAAAHTRVDVSGLVVAPGFIDSHTHDDNYLLRRRDMTPKISQGVTTVVTGNCGISLAPLAHANPPAPLDLLDEGGSYRFERFADYLDALRATPAAVNAACMVGHSTLRAAVMPDLQRAATDEEIAAMRDLAEEAMASGAIGISTGAFYPPAARATTEEIIEVCRPLSAHGGIYATHMRDEGEHIVAALEETFRIGRELDVPVVISHHKVMGQPNFGRSRETLPLIEAAMARQDVSLDAYPYVAGSTMLKQDRVLLAGRTIITWCKPFPELSGRDLDEVAAERGKSKYDVVPELQPAGAIYFMMDEPDVQRILAFGPTMIGSDGLPHDERPHPRLWGTFPRVLGHYARDLGLFPLETAVWKMTGLTAARFGLAGRGQLQAGYFADLVVFDPATVADTATFEHPTERAAGIHSVYVNGAPVWQEQAFTGQHAGRVLARTAA
What is the function of this protein?
Has a wide specificity; hydrolyzes N-acyl derivative of neutral D-amino acids.
What are the official names of this protein?
D-aminoacylase, N-acyl-D-amino-acid deacylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. N-acyl-D-amino-acid deacylase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL11_PSEAB
Sequence: MAKKIQAYIKLQVKAGQANPSPPVGPALGQHGVNIMEFCKAFNAKTQGQEPGLPTPVIITVYSDRSFTFETKSTPAAVLLKKAAGITSGSARPNSQKVGTVTRAQLEEIAKTKQADLTAADLDAAVRTIAGSARSMGLNVEGV
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RECR_RHIWR
Sequence: MSSPEIETLTQALAKLPGLGPRSARRAVLHLLKKREAALGPLLRALEAVNDKLTSCHVCGNVDTGDPCGICADPRRDARMLCVVEEVADLWALDRSRLFPGRFHVLGGRLSALEGIRPEDLSIDLLIGRIAAGGIDEVVLAMNATLEGQTTAHYIADRLESFPVRLTQLAHGLPVGGELDYLDEGTLAQALRARRPVS
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: MURA_FERNB
Sequence: MGSIIVERSKLSGEVEISGAKNSALPLLAAALLTEEEVTLYKVPVLSDVETMIDILRTTGKDVFFDKHKGIVKISGKISITHIQYELVRKMRASFNVLGPIAALVGEASTPLPGGCAIGARPVDFHLEGLKKIGFEISFDHGEIRAKRGKKEEESVVYLPFPSVGATEHIMSTAAILPGKTIIENAAMEPEIIDLQNLLNKMGAKVYGAGTSKIIVEGVEKLHGCEHTIIPDRIEAGTYIIGILATKGEGIVKNIIPEHLEALWFVLEKTGAIIKKGENEVEVKSPDKWYGCDINVLPYPGFPTDLQPQILVYLSLADGSSTVTENVFKTRFAHVAELVRMGANMKIIENTVFINGVEKLYGTTVMGTDLRATAALVIAGLAAEDRTEVTSVEHIFRGYENVIEKFSKLGASIKYIPGGVPEI
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YDIO_BACSU
Sequence: MTNFILNENKQLSLAIEDENIENFYIDGTDLVRKIIRRSGSGVTSRVPVLSTQDLENKNLHELYDESWLRMKNRPNTELTTESINIADLFSGCGGLSLGVWEACRALGINPRFSFACDLNEAALSVYEKNFSPDFSLNESIEKHINGELGAPLTVEEQRIKDKVKKIDFILAGPPCQGHSDLNNHTRRKDPRNALLMRVSRVIELFQPSSVLVENVPGIIHDKSGSFKEFKNHLKTQGYYFDEIVLNAEKLGVSQARRRYFIFASKTPVSSLNQINEFYSTNSRPISWAISDLVENVGDDIFNTASEHSLENKRRIEYLFENNLFELPNSERPDCHRLKPHSYKSVYGRMYWDRPAPTITRGFGSTGQGRFVHSLLKRTITPHEAARIQFFPDFFNFGDLRRRQYQDVIGNAVPSKLSYLLALHQLR
What is the function of this protein?
A methylase, recognizes the double-stranded sequence 5'-YTCGAR-3', methylates C-3 on both strands, and protects the DNA from cleavage by the BsuMI endonuclease.
What are the official names of this protein?
Type II methyltransferase M1.BsuMI, M1.BsuMI, BsuMI modification methylase subunit YdiO, Cytosine-specific methyltransferase M1.BsuMI.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: PCDBE_HUMAN
Sequence: MEIRGALDLRKRQVLIFLVLLGLSRAGTESAHYSVAEETEIGSFVANLARDLGLGVEELSSREARVVSDDNKKYLHLDLLTGNLLLNEKLDRDELCGSTEPCVLHFQVVLENPLQFFRFELCVKDINDHSPTFLDKEILIKISEGTTVGATFLMESAQDLDVGSNSLQNYTISPNSHFYIKIPDSSDRKIYPELVLDRALDYEQEAELRLTLTAVDGGSPPKSGTTLVLIKVLDINDNAPEFPQSLYEVQVPEDRPLGSWIATISAKDLDAGNYGKISYTFFHASEDIRKTFEINPISGEVNLRSPLDFEVIQSYTINIQATDGGGLSGKCTLLVKVMDINDNPPEVTISSITKRIPENASETLVALFSILDQDSGDNGRMICSIQDNLPFFLKPTFKNFFTLVSEKALDRESQAEYNITITVTDLGTPRLKTEYNITVLLSDVNDNAPTFTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDRHLPLASLVSINADNGHLFALRSLDYEALQEFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRCSVPEGPFPGHLVDVSGTGTLSQSYQYEVCLTGGSGTNEFKFLKPIIPNFQVHDTGRNMGEIENFRNSFGLNIQ
What is the function of this protein?
Potential calcium-dependent cell-adhesion protein.  May be involved in the establishment and maintenance of specific neuronal connections in the brain.
What are the official names of this protein?
Protocadherin beta-14, PCDH-beta-14.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: ACP_SALPC
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YEBF_SHIDS
Sequence: MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIAASVKRDYQQNRVARWADDQKIVGQADLVAWVSLQDIQGKDDKWSVLLTVSGKSADIHYQVSVDCKAGMAEYQRR
What are the official names of this protein?
Protein YebF.
What is the protein family that this protein belongs to?
Belongs to the YebF family.
What are the subcellular locations of this protein?
Secreted.
Protein: DRTS_TRYCR
Sequence: MSLFKIRMPETVAEGTRLALRAFSLVVAVDEHGGIGDGRSIPWNVPEDMKFFRDLTTKLRGKNVKPSPAKRNAVVMGRKTWDSIPPKFRPLPGRLNVVLSSTLTTQHLLDGLPDEEKRNLHADSIVAVNGGLEQALRLLASPNYTPSIETVYCIGGGSVYAEALRPPCVHLLQAIYRTTIRASESSCSVFFRVPESGTEAAAGIEWQRETISEELTSANGNETKYYFEKLIPRNREEEQYLSLVDRIIREGNVKHDRTGVGTLSIFGAQMRFSLRNNRLPLLTTKRVFWRGVCEELLWFLRGETYAKKLSDKGVHIWDDNGSRAFLDSRGLTEYEEMDLGPVYGFQWRHFGAAYTHHDANYDGQGVDQIKAIVETLKTNPDDRRMLFTAWNPSALPRMALPPCHLLAQFYVSNGELSCMLYQRSCDMGLGVPFNIASYALLTILIAKATGLRPGELVHTLGDAHVYSNHVEPCNEQLKRVPRAFPYLVFRREREFLEDYEEGDMEVIDYAPYPPISMKMAV
What is the function of this protein?
Bifunctional enzyme.  Involved in de novo dTMP biosynthesis.  Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP.
What are the official names of this protein?
Bifunctional dihydrofolate reductase-thymidylate synthase, DHFR-TS.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the thymidylate synthase family.
Protein: QUEC_KINRD
Sequence: MDRPAVVLLSGGLDSTTVLAIAKSQGFTPYALSFAYGQRHAVELDAARRVATALGAAGHVIATIDLTVFGGSALTADIAVPKHDTVEDLQADIPITYVPARNTIFLSYALAYAEVVGAGDIFIGVNALDYSGYPDCRPEYVDAFQAMGRLATRAGVQGTELTIHAPLMQMTKADIVRAGLALGVDYGMTSSCYDPDAAGHPCGHCDSCLLRLNGFAEAGSTDPLPYRGA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RIMP_AQUAE
Sequence: MEINREEIEKKVKEIVEPVIRGMGFKLFDVEFKPEGRGWVLRIIADKEGGITIKDCEEISRKVSALLDVEDIIPFSYLLEITSPGLTRPLTKVEHYDFFKGRLVKLILKEPIEGKREVVGYIEDVKNGIIDIREKEKGKVLHIPFSAIAKGRLEIEGW
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HNRPK_BOVIN
Sequence: METEQPEETFPNTETNGEFGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGPERILSISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPQSTDRVVLIGGKPDRVVECIKIILDLISESPIKGRAQPYDPNFYDETYDYGGFTMMFDDRRGRPVGFPMRGRGGFDRMPPGRGGRPMPPSRRDYDDMSPRRGPPPPPPGRGGRGGSRARNLPLPPPPPPRGGDLMAYDRRGRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGPIITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSEDRIITITGTQDQIQNAQYLLQNSVKQYADVEGF
What is the function of this protein?
One of the major pre-mRNA-binding proteins.  Binds tenaciously to poly(C) sequences.  Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences.  Can also bind poly(C) single-stranded DNA.  Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression.  When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction.  As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53.  This interaction is necessary for the induction of apoptosis, but not cell cycle arrest (By similarity).  As part of a ribonucleoprotein complex composed at least of ZNF827, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation (By similarity).
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein K, hnRNP K.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleoplasm. Cell projection, podosome.
Protein: RS7_SACEN
Sequence: MPRKGPAPKRPLHADPVYSSPLVTQLVNKVLVDGKRSLAERIVYAALEGCRDKTGTDPVVTLKRALDNVKPTLEVRSRRVGGATYQVPIEVRAGRSTTLALRWLVTYSRQRREKTMVERLMNELLDASNGLGASVKKREDTHKMAESNKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RM04_EMENI
Sequence: MHRQSVVRLSRQLGAFPLVELPPPYLAPSLHFPLNRSSVQTSNFSSTAPAAGHGKDLNKSRAVSAIHRTGPRFKLGASKYPLPKPVSPEKLEKRESTPDHGLWGFFPKDRSALSTPEYDNAHGRSWSIQELREKSWEDLHSLWWVCLKEKNRIATSNLERKRLKAGYGEWEANQRLRTIRVTQLNIKHVLRERWYAWEDAQNLYKKGYRPQNEDTEESA
What are the official names of this protein?
54S ribosomal protein L4, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YD210_YEAST
Sequence: MSQQQGYYQQGPPQQGYYQQGPPQQGYYQQGPPQQGYPQQQPVYVQQGQPKEESCLDSCLKCLCCCFLLELVCDN
What are the official names of this protein?
Cysteine-rich and transmembrane domain-containing protein YDR210W.
What is the protein family that this protein belongs to?
Belongs to the CYSTM1 family.
Protein: RL14_SYNJB
Sequence: MIQQQTMLTVADNTGARKMMCIRVLGSSGRRYASLGDVIIGVVKDALPNMPVKKSDVVKAVVIRTVDTVRRPDGMCIRFDDNAAVIINNDGNPRGTRVFGPVARELREKNFTKIISLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: Y204_PICTO
Sequence: MDRDDELDEIRRRKMAEYQNMMQERAYEEEQKKAAAEEEARRQQILRQILSPEARERLSRLKLVRPDLVENVENQLIQLAGMGRINKVISDNELKSILLRLTENRHETRIERR
What are the official names of this protein?
DNA-binding protein PTO0204.
What is the protein family that this protein belongs to?
Belongs to the PDCD5 family.
Protein: 708C1_FAGES
Sequence: MMGDLTTSFPATTLTTNDQPHVVVCSGAGMGHLTPFLNLASALSSAPYNCKVTLLIVIPLITDAESHHISSFFSSHPTIHRLDFHVNLPAPKPNVDPFFLRYKSISDSAHRLPVHLSALSPPISAVFSDFLFTQGLNTTLPHLPNYTFTTTSARFFTLMSYVPHLAKSSSSSPVEIPGLEPFPTDNIPPPFFNPEHIFTSFTISNAKYFSLSKGILVNTFDSFEPETLSALNSGDTLSDLPPVIPIGPLNELEHNKQEELLPWLDQQPEKSVLYVSFGNRTAMSSDQILELGMGLERSDCRFIWVVKTSKIDKDDKSELRKLFGEELYLKLSEKGKLVKWVNQTEILGHTAVGGFLSHCGWNSVMEAARRGVPILAWPQHGDQRENAWVVEKAGLGVWEREWASGIQAAIVEKVKMIMGNNDLRKSAMKVGEEAKRACDVGGSSATALMNIIGSLKR
What is the function of this protein?
UDP-glucose-dependent glucosyltransferase catalyzing the C-glucosylation of 2-hydroxyflavanones (2-hydroxynaringenin, 2-hydroxyeriodictyol and 2-hydroxypinocembrin) and phloretin (PubMed:25142187).  No activity with flavanones, flavones or flavonols (PubMed:25142187).  Exhibits C-glycosylation activity toward 2',4',6'-trihydroxyacetophenone and phloretin using UDP-glucose as sugar donor (PubMed:32699169).  Can use UDP-galactose as sugar donor, but catalytic efficiency is 14-fold lower toward UDP-galactose than toward UDP-glucose (PubMed:32699169).
What are the official names of this protein?
UDP-glycosyltransferase 708C1, C-glucosyltransferase a, FeCGTa, UDP-glucose:2-hydroxyflavanone C-glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.