PharMolix/UniProtQA huggingface dataset:
Protein: ARGB_ECOL6
Sequence: MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRQLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTNEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_SYNPW
Sequence: MAIVSSNAASQRPRPDRGPDRVPNRVVDGARQAEDDRDPGRVGAKEDSLRPKRLADYIGQRELKQVLGIAVQAAVGRGEALDHVLLYGPPGLGKTTMAMVLAEELGVTCRITSAPALERPRDIVGLLVTLQPKDLLFIDEIHRLSRVAEELLYPAMEDRRLDLTVGKGSTARTRALDLPPFTLVGATTRAGALSSPLRDRFGLIQRLEFYGLEDLQAIVERAAGLLDLDLSAAACTEIARRCRGTPRIANRLLRRVRDVACVRACAGRIDQALVDEALTLHRVDGRGLDASDRRLMELLLQSHGGGPAGLDTLAAALGEDPATLESVVEPYLLQLGFLQRTPRGRVVTAAGRGHLGWPYPQEQAA
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: CLL2_ARATH
Sequence: MDSRRMSRPRQIKFEEGWSNIQKGITKLIRILEGEPEPTFYFSECFKLYTIIYDMCVQRSDYSQQLYEKYRKVIEDYTIQTVLPSLREKHDEDMLRELVKRWNNHKIMVKWLSKFFVYIDRHLVRRSKIPIPSLDEVGLTCFLDLVYCEMQSTAKEVVIALIHKEREGEQIDRALVKNVLDIYVENGMGTLEKYEEDFESFMLQDTASYYSRKASRWTEEDSCPDYMIKVEECLKMERERVTHYLHSITEPKLVEKIQNELLVMVTKNRLENEHSGFSALLRDDKKNDLSRIYRLYLPIPKRLGRVADLFKKHITEEGNALIKQADDKTTNQLLIELHNKFIVYVIECFQNHTLFHKVRVLFMCVYLFQQYYIE
What are the official names of this protein?
Putative cullin-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the cullin family.
Protein: GUAA_HAMD5
Sequence: MIKNIDRHRILILDFGSQYTQLLARRIREMGVYSELWPWDVAAERIQAFHPQGIILSGGPESATENDTPRAPDIIFTLGVPVLGICYGMQTMAIQLGGTVSNTHQGEFGYAPLALKNKNALIDGLEDFVNANNEPCLKVWMSHADKVTKLPEHFTCIASTETCPIAIMAHPEKHFYGVQFHPEVTHTLQGQSLLKRFVLQICQCEPLWTPRNIIDQTLSELKDQIGDDQVILGLSGGVDSAVTAILLHRAIGKSLTCVFVDNGLLRLNESQQVLNIFQDQFGLNIIHVSAANRFMNALKGIQDPEKKRKVIGRVFVDIFDEQAAKQKGVKWLAQGTIYTDLVESAASGTAKSHLIKSHHNVAGLPKEMKLGLIEPLKELFKDEVRQLGLELGLPNAMLHRHPFPGPGLGVRVLGEVKQEYCDLLRQADAIFIQELQKAELYQKVSQAFAVFLPIRSVGVMGDGRKYEWVIALRAIETVDFMTAHWAELPYDLLGRVSNRIINEVKGISRVVYDISGKPPATIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: MURI_TREPA
Sequence: MSDRREQFQYAFLDSGIGGLPYAHALRVRVPEASLVYVADRVYFPYGNKSSAQIIARASAVLQKVQTNFSPHIVVLACNSMSVNALEFLRAQVSVPVVGVVPAIKQAVACSHKKHIGVLATQCTITHPYTACLRAQFGAGCVFQMRADARLIECLERGLIFEVEDMQREAVARSVMPFQEAGVDVLVLACTHFVHVRHLFQDCVGTSCTVVDSLEGVVRRTLRLCPPQSQLRGNAACYVTGARDAVCAARYARYAQHFGLRWAGFLDV
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: NOP56_PONAB
Sequence: MVLLHVLFEHAVGYALLALKEVEEISLLQPQVEESVLNLGKFHNIVRLVAFCPFASSQVALENANAVSEGVVHEDLRLLLETHLPSKKKRVLLGVGDPKIGAAIQEELGYNCQTGGVIAEILRGVRLHFHNLVKGLTDLSACKAQLGLGHSYSRTKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYGYHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEELTMDGAKAKAILDASRSSMGMDISAIDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPASTVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEVPTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAMVQAEEAAAEITRKLEKQEKKRLKKEKKRLAALALASSENSSSTPEECEETSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKSFSKEELMSSDPEETAGSTSIPKKKKSSPKGETVNDPEEAGHRSGSKKKRKFSKEEPVSSGPEEAAGKSSSKKKKKFHKASQED
What is the function of this protein?
Involved in the early to middle stages of 60S ribosomal subunit biogenesis.  Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles.  Required for the biogenesis of box C/D snoRNAs such U3, U8 and U14 snoRNAs.  Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit.  During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
What are the official names of this protein?
Nucleolar protein 56, Nucleolar protein 5A.
What is the protein family that this protein belongs to?
Belongs to the NOP5/NOP56 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm. Nucleus, nucleoplasm.
Protein: CCO_MYCTO
Sequence: MTTAQAAESQNPYLEGFLAPVSTEVTATDLPVTGRIPEHLDGRYLRNGPNPVAEVDPATYHWFTGDAMVHGVALRDGKARWYRNRWVRTPAVCAALGEPISARPHPRTGIIEGGPNTNVLTHAGRTLALVEAGVVNYELTDELDTVGPCDFDGTLHGGYTAHPQRDPHTGELHAVSYSFARGHRVQYSVIGTDGHARRTVDIEVAGSPMMHSFSLTDNYVVIYDLPVTFDPMQVVPASVPRWLQRPARLVIQSVLGRVRIPDPIAALGNRMQGHSDRLPYAWNPSYPARVGVMPREGGNEDVRWFDIEPCYVYHPLNAYSECRNGAEVLVLDVVRYSRMFDRDRRGPGGDSRPSLDRWTINLATGAVTAECRDDRAQEFPRINETLVGGPHRFAYTVGIEGGFLVGAGAALSTPLYKQDCVTGSSTVASLDPDLLIGEMVFVPNPSARAEDDGILMGYGWHRGRDEGQLLLLDAQTLESIATVHLPQRVPMGFHGNWAPTT
What is the function of this protein?
Catalyzes the oxidative cleavage of several carotenoids and apocarotenoids in vitro.
What are the official names of this protein?
Carotenoid cleavage oxygenase, CCO, Carotenoid 13,14/15,15'-oxygenase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
Protein: RL5_PSEPG
Sequence: MARLKEIYRNEIAPKLKEELKLSNVMEVPRVTKITLNMGLGEAIGDKKVIEHAVADLEKITGQKPVVTFARKSIAGFKVREGWPIGVKVTLRSDKMYEFLDRLLAISLPRVRDFRGLNAKSFDGRGNYSMGVKEQIIFPEIDYDKIDALRGLDITLTTTARSDDEGRALLRAFKFPFRN
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: PDXY_PSEAE
Sequence: MPRTPHLLAIQSHVVFGHAGNAAAVFPMQRIGINVWPLNTVQFSNHTQYGRWTGQVLPPEQIPALVDGIAGIGELGNCDAVLSGYLGSAAQGRAILDVVARIKQANPRALYLCDPVMGHPEKGCIVAPEVSDFLLEEAAAVADYLCPNQLELDSFCDRQPNSLADCVEMARSLLARGPRAILVKHLNYPGKAGDTFEMLLVAADQAWHLQRPLLAFPRQPVGVGDLASGLFLSRLLLGDDLRNAFEFTGAAVHEVLLETQACGSYELELVRAQDRIAHPRVRFDAVRL
What is the function of this protein?
Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxal to PLP.
What are the official names of this protein?
Pyridoxal kinase PdxY, PL kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxY subfamily.
Protein: PYRF_STAHJ
Sequence: MKDLPIIALDFESATKVNTFLDQFDEPLFVKIGMELFYQAGPDLIKSIKSRGHDIFLDLKLHDIPNTVEKAMEGLGKLDVDLVNVHAAGGTDMMKAAVRGLHKYSNDTKIIAVTQLTSTTEEMLRNEQNIQTTIEEAVLNYATLTQQAGLDGVVCSPLEAELLTNKLGSNFLKVTPGIRPQGAAVDDQKRITTPEDAKQLGATHIVVGRPITQSENPVESYHTIKESWLG
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: NUOCD_SALNS
Sequence: MVNNMTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATRTGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMMPQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEVLTFKPEDWGMKRGTDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENFDFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: LPXB_ECO55
Sequence: MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDFNITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVPCRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: DER_FRATM
Sequence: MSFLVAIVGRANVGKSTLFNVLTNSHDALVFDFEGVTRDRQYGQAKYDDLDYLVVDTGGISDKDVGFDEFMAKQSQIAIDEANLVFFVVDGRSGLTTGDEYVASLLRQKDKKVVVVVNKVDGTDEEAAMAEFYSFGFDKVFAISAAHRRNTQKLVDKFLKKPLNEYYQDYTQTQEHKEQQRHGIHFSLIGRPNVGKSTLTNRMLGEDRVVVFDMPGTTIDSVSIPFERHGQKYTIVDTAGVRKRGKVKQTLEKFSVIKTLQAIQDSNVVVAVVDARQGISDQDLSLIHFAIKNGRALVLAVNKWDGMTEEDRIQVKQDLKRKLFFLQDYVDIHFISALHGTNVGHVFESIDTAYACANKKITTADATCLMQLAVEAHSLPMVGKFRIKLKYAHVGGHNPPVIVIHGNQVSRLPNSYKRYLENFFREALDFRGTPIVFEFKQSENPFADRKNKRSKDEGSKSKKVK
What is the function of this protein?
GTPase that plays an essential role in the late steps of ribosome biogenesis.
What are the official names of this protein?
GTPase Der, GTP-binding protein EngA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
Protein: ARGJ_NITEU
Sequence: MPVNIPPLLPEQLLPIPGLSLGTAEASIKRPGRKDILVITLAENTRVAGVFTRNRFCAAPVTVARSHLTGSLPIRALVINTGNANAGTGQSGIDHAHATCASLARLIGCQTQQVLPFSTGVIMEPLPVEKIITHLPQALANLAPDNWFAAAQAIMTTDIVPKGVSRQIQINGTTVTITGIAKGSGMIHPNMATMLGYIATDAAVTQPLLDDLVRYATDRSFNCVTVDGDTSTNDALILMATGQAGNTPITVSTDPAFISLQAAITEVAALLAQMIVRDGEGATKFITVQVESGKTREECTKVAYAIAHSPLIKTACFASDPNLGRILAAIGYAGIEDLDVNLVQLYLGNILVAEHGGRAASYREEDGQRIMQAPEITIQVKLNRGNASTTVWTCDLSYDYVKINADYRS
What is the function of this protein?
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
What are the official names of this protein?
Arginine biosynthesis bifunctional protein ArgJ.
What is the protein family that this protein belongs to?
Belongs to the ArgJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OADB1_SALTI
Sequence: MESLNALLQGMGLMHLGAGQAIMLLVSLLLLWLAIAKKFEPLLLLPIGFGGLLSNIPEAGMALTALESLLAHHDAGQLAVIAAKLNCAPDVHAIKEALALALPSVQNQMENLAVDMGYTPGVLALFYKVAIGSGVAPLVIFMGVGAMTDFGPLLANPRTLLLGAAAQFGIFATVLGALTLNYFGLIAFTLPQAAAIGIIGGADGPTAIYLSGKLAPELLGAIAVAAYSYMALVPLIQPPIMRALTSEKERKIRMVQLRTVSKREKILFPVVLLLLVALLLPDAAPLLGMFCFGNLMRESGVVERLSDTVQNGLINIVTIFLGLSVGAKLVADKFLQPQTLGILLLGVIAFGIGTAAGVLMAKLLNLCSKNKINPLIGSAGVSAVPMAARVSNKVGLESDAQNFLLMHAMGPNVAGVIGSAIAAGVMLKYVLAM
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
What are the official names of this protein?
Oxaloacetate decarboxylase beta chain 1.
What is the protein family that this protein belongs to?
Belongs to the GcdB/MmdB/OadB family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RPOA_PSEA6
Sequence: MSGSVTEFLKPRLVEIDNVSPTRAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDVIEILLNLKGLAVRLEGKTEATLTLVKSGAGPVLAGDIQHDGDVEIVNPSHVLCTLTGEAELSMRIKVEMGRGYVPASTRRSSEEDDRPIGRLLVDASFSPVSRISYNVESARVEQRTDLDKLIIDMETNGTIDPEEAIRRSATILAEQLDAFVELRDMSEPVEKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIQYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPESIAEKD
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha, RNAP subunit alpha, RNA polymerase subunit alpha, Transcriptase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: ST6B1_PANTR
Sequence: MADKSKFIEYIDEALEKSKETALSHLFFTYQGIPYPITMCTSETFQALDTFEARHDDIVLASYPKCGSNWILHIVSELIYAVSKKKYEYPEFPVLECGDSEKYQRMKGFPSPRILATHLHYDKLPGSIFKNKAKILVIFRNPKDTAVSFFHFHNDVPDIPSYGSWDEFFRQLMKGQVSWGSYFDFAINWNKHLDGDNVKFILYEDLKENLAAGIKQIAEFLGFFLTGEQIQTISVQSTFQAMRAKSQDTHGAVGPFLFRKGEVGDWKNLFGEIQNQEMDEKFKECLAGTSLGAKLKYESYCQG
What is the function of this protein?
Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of thyroxine.  Involved in the metabolism of thyroxine (By similarity).
What are the official names of this protein?
Sulfotransferase 6B1, ST6B1, Thyroxine sulfotransferase.
What is the protein family that this protein belongs to?
Belongs to the sulfotransferase 1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: EZRA_BACVZ
Sequence: MELVIGLLVILLALFAAGYFFRKKIYTEIDRLESWKIEILNRSIVEEMSKIKHLKMTGETEEFFERWREEWDEIVTAHLPKVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESNIEGILREISDLVTSEEKSRGEIEQVRERYSKARKNLLAYSHLYGELYNSLETDLDEIWSGIKEFEEETESGNYIKARKVLLEQDRRLDQLQTYIDDVPKLLADCKQTVPNQIAKLKDGYREMTEKGYKLEHIQIEKELDTLTNQVKRAENALLEELDVDEASAILQLIDETIQSMYEQLEGEVEAGQSVLSKMPELIIAYEKLEEEKDRTKTETELVKESYQLTAGEIGRQHAFEKQLETIGRLLEQAREKLDGEHVAYSLLIEEVEAIEKQLEEAQKEHAEYRENLQALRKEELQARETLMHLRKTISDTARMLQKSNVPGIPEQVKDKLETANHHIEETVSQLEELPLNMEEAAKHLDEAEKVVEEVSEEAEDLVIQVKLIERIIQYGNRFRSQNHILSEQLKEAERLFYAYSYNEAYEMAADAVEKAAPGAVKKIKADQSAS
What is the function of this protein?
Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation.  Inhibits FtsZ ring formation at polar sites.  Interacts either with FtsZ or with one of its binding partners to promote depolymerization.
What are the official names of this protein?
Septation ring formation regulator EzrA.
What is the protein family that this protein belongs to?
Belongs to the EzrA family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein. Note=Colocalized with FtsZ to the nascent septal site.
Protein: GLUQ_XANOR
Sequence: MPSPSYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGASERQLRTLTAFGLHSDLPVIRQSERDAAYTAAINRLLETGQAFECSCSRADLAGMGGIHHACVAPLGARRAVRLRVPPQSPVGFDDALHGRVLQDVYADVGDVVLRRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQMLLQRALGVPQPRYLHLPLMLDGDGRKLSKSHGAPALDDTDPLPALHAAWAGLGQRPDALPRRATVTTLLQQAVRHFSPQLLPRQRQRDRATCAYERQRD
What is the function of this protein?
Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp).  Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.
What are the official names of this protein?
Glutamyl-Q tRNA(Asp) synthetase, Glu-Q-RSs.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
Protein: DUT_RHOPT
Sequence: MTQKITVSIRHLPHGEGLPLPEYQTAHAAGLDLIAAVPQDAPLTLQPGRYVLVPTGLTIALPENYEAQVRPRSGLAAKHGVTVLNAPGTIDADYRGEIGVLLINHGTEPFAIRRGERIAQMVIAPVSRAQFVAVEALPESGRGAGGFGSTGR
What is the function of this protein?
This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
What are the official names of this protein?
Deoxyuridine 5'-triphosphate nucleotidohydrolase, dUTPase, dUTP pyrophosphatase.
What is the protein family that this protein belongs to?
Belongs to the dUTPase family.
Protein: AATC2_HUMAN
Sequence: MPTLSVFMDVPLAHKLEGSLLKTYKQDDYPNKIFLAYRVCMTNEGHPWVSLVVQKTRLQISQDPSLNYEYLPTMGLKSFIQASLALLFGKHSQAIVENRVGGVHTVGDSGAFQLGVQFLRAWHKDARIVYIISSQKELHGLVFQDMGFTVYEYSVWDPKKLCMDPDILLNVVEQIPHGCVLVMGNIIDCKLTPSGWAKLMSMIKSKQIFPFFDIPCQGLYTSDLEEDTRILQYFVSQGFEFFCSQSLSKNFGIYDEGVGMLVVVAVNNQQLLCVLSQLEGLAQALWLNPPNTGARVITSILCNPALLGEWKQSLKEVVENIMLTKEKVKEKLQLLGTPGSWGHITEQSGTHGYLGLNSQQVEYLVRKKHIYIPKNGQINFSCINANNINYITEGINEAVLLTESSEMCLPKEKKTLIGIKL
What are the official names of this protein?
Putative aspartate aminotransferase, cytoplasmic 2, Glutamate oxaloacetate transaminase 1-like protein 1, Transaminase A-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IPDB_RHOJR
Sequence: MSETITEVTRAEYCAIACADIFSGAGEIMASPMATLPLIGARLARLTTEPDLLITDGEALIFADTPAVGAKAPIEGWMPFRKVFDVVASGRRHVVMGANQIDRHGNQNLSAFGPLQQPTRQMFGVRGAPGNTINHPTSYWVGKHTSRVFCDTVDIVSGVGYDQIDPENPAYRFHHLHRVVSNLGVFDFGGPDHTFRALSLHPGVTADQVADNTSFEVAGLADAGVTREPTDEELRLIREVLDPRSLRDREVSV
What is the function of this protein?
Involved in the final steps of cholesterol and steroid degradation (PubMed:28377529, PubMed:29581275).  Opens the last steroid ring of cholesterol by catalyzing the hydrolysis of (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) to 6-methyl-3,7-dioxodecanedioyl-CoA (MeDODA-CoA) (Probable) (PubMed:29581275).
What are the official names of this protein?
Cholesterol ring-cleaving hydrolase IpdB subunit, (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase beta subunit, COCHEA-CoA hydrolase beta subunit.
What is the protein family that this protein belongs to?
Belongs to the 3-oxoacid CoA-transferase subunit B family.
Protein: REPZ_ECOLX
Sequence: MAGLKNTPYNAVHWSQLAPEEQIRFWEDYEAGRATTFLVEPERKRTKRRRGEHSTKPKCENPSWYRPERYKALKGQLGHAYNRLVKKDPVTGEQSLRMRMSRHPFYVQKRTFVGRKYAFRPEKQRLLDAIWPVLVSFSDAGTHTVGMSVTRLAEEISPKDSEGHVIPELEVTVSRLSRLLAEQVRFGVLGVSEETMWDREHRQRLPRYVWITPAGWQMLGVDMVKLHEQQQKRLRESEIRQQLIREGVLREDEDISVHAARKRWYLQRSQDALKKRREKAAASKRANRLKKLPVDQQIYEMAEYLRKRLPPDEAYFCSDDHLKRLAIRELRQLELTLAAPPPH
What is the function of this protein?
Probably functions as an initiator for the IncI1 ColIb-P9 replicon.
What are the official names of this protein?
Replication initiation protein, Replication-associated protein.
Protein: ATPB_FLAPJ
Sequence: MSKVIGKVSQIIGPVVDVVFNGKDVELPKIYDSLEITKKDGTLLVLEVQSHIGENTVRTISMDSTDGLSRGYEVVGTGNPIKMPIGADVYGRLFNVIGDAIDGLGNLPKDGDNGMSIHRQAPRFEDLSTSSEVLFTGIKVIDLIEPYSKGGKIGLFGGAGVGKTVLIQELINNIAKGHGGLSVFAGVGERTREGNDLLREMLESGIIKYGDDFMHSMENGGWDLSKVDMPGMRESKATFVFGQMNEPPGARARVALSGLSIAEYFRDGAGSDQGKDVLFFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGAMQERITSTNKGSITSVQAVYVPADDLTDPAPATTFAHLDATTVLSRKIAELGIYPAVDPLDSTSRILTPQILGDEHYDCAQRVKEILQKYKQLQDIIAILGMEELSEEDKLSVSRARRVQRFLSQPFHVAEQFTGLKGVLVDIKDTIKGFNMIIDGELDHLPEAAFNLKGTIEEAIEAGEKMLAEA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CHEB2_LEPIC
Sequence: MNYEAIVIGVSAGGINAMKTILPTLPTQFGIPIVIVQHIGARSDGEWFRILEKLCNIKIKEAEEKEEIKSGMVYVAPPNYHLLIEKDKTFSFSIGERVNFSRPSIDVLFETASEVYEDKLIGVILTGANSDGAQGLKKIKENGGLAVVQDPLTAEIALMPRSAIEATSVDYVLSLEKIAELFIRLDQNNLEQR
What is the function of this protein?
May be involved in chemotaxis.
What are the official names of this protein?
Putative protein-glutamate methylesterase/protein-glutamine glutaminase.
What is the protein family that this protein belongs to?
Belongs to the CheB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDPA_PSEPG
Sequence: MPIRHCIVHLIDKKPDGSPAVLHARDSELAASDAIENLLADLNDSYNAKQGKAWGFFHGESGAYPLSGWLKQYLDEEKDFTAFSRVAVEHLQKLMEESNLSTGGHILFAHYQQGMTEYLAIALLHHSEGVAVNAELDVTPSRHLDLGQLHLAARINLSEWKNNQNSKQYISFIKGKNGKKVSDYFRDFIGCQEGVDGPGETRTLLKAFSDFVESEDLPEESAREKTQTLVEYATTQTKLGEPVTLEELSSLIDEDRPKAFYDHIRNKDYGLSPEIPADKRTLNQFRRFTGRAEGLSISFEAHLLGDKVEYDEAAGTLIIKGLPTTLVDQLKRRKD
What are the official names of this protein?
Nucleoid-associated protein PputGB1_0980.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YL082_MIMIV
Sequence: MATSIDLVEAERRYRTICSSWNECITFQQHQAAVEEYKELHQLLFPSSCQYIPGWLTPEQREAKKQAEIAKKLRKLELKEEFKFLIDSALSKSLTKISDQDINDLPWTFMSTLNGLVNPGKFGISNIFAGQKDISVQSKEKFELHVRRALDETFHWCIFPEKLDDFTKTFSEKLSFRLKYS
What are the official names of this protein?
Uncharacterized protein L82.
Protein: RFCL_METS3
Sequence: MLWTDKYRPKTLDEVVGNNKEKALIQKWVDNWKAGNPQKPLLLVGPPGIGKTTLAQAIAREFSEYIELNASDKRSQDVIKSTIGESSSSKSLFGDDYKLLILDEVDGIHGTNDRGGVRAIGDIIKKAKHPMILIANDFYSKRIASLKTKCDVLKMSKVRSPSINKLLKQIAINEGIKANPAALKELAKKSNGDMRSAINTFQALANQNEVLELSDIENITTKDDRSTIINGVTAVLKSKNPNHVKKALMVEEDPTLVMEYIAENIPREYTKKKEIKKAYENIAKADLYFGRARSSRYYGYWKYATDFMGVGVSDAKDETYKKFTRITSPTVFTLMGRNRGKRNLRDRIAEKMSQKLHISHSVAISMFPYLEIMFENNELAWEISDFLGFEEDEIKRFRTRKIPKKVIEKMEKQKAQKRVEQRDARAQEIQDGLMATIPPQKEVKEEPTEEIQEEVVDEIKEETVEEIQEESQKEVEEKPKKKTDKQVSLFNF
What is the function of this protein?
Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.
What are the official names of this protein?
Replication factor C large subunit, RFC large subunit, Clamp loader large subunit.
What is the protein family that this protein belongs to?
Belongs to the activator 1 small subunits family. RfcL subfamily.