PharMolix/UniProtQA huggingface dataset:
Protein: POTC_MYCGE
Sequence: MKKHFKNLIKNSYFFLLITLIYLPLLIVVLVSLNGSSSRGNIVLDFGNVLNPNPDSKSAYLRLGETDFATPLINSIIIGVITVLVSVPIAVISAFALLRTRNALKKTIFGITNFSLATPDIITAISLVLLFANTWLSFNQQLGFFTIITSHISFSVPYALILIYPKIQKLNPNLILASQDLGYSPLKTFFHITLPYLMPSIFSAVLVVFATSFDDYVITSLVQGSVKTIATELYSFRKGIKAWAIAFGSILILISVLGVCLITLQKYLREKRKEIIKIRQWKNS
What is the function of this protein?
Required for the activity of the bacterial transport system of putrescine and spermidine.
What are the official names of this protein?
Spermidine/putrescine transport system permease protein PotC homolog.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL35_SACD2
Sequence: MSKAKTHSGAAKRFKKTASGYKHKHAFKSHILTKMTTKRKRQLRGTSLLNAADKPAVDRMLRAN
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: TRPD_FRATW
Sequence: MISLKSIVDKLYNLEDLSYQESYQLFDYFIKGQIELPLQTSILTALKLKKETSIEIAAAVEALFDNTKEFPKIKGDLAGIVGTGGDGFNTINISTTAAIVAATAGYKVAKHGGRSVSSKSGSFDLLESFGVNIELAPDQTKQCLELYNLGFLFVPFYSDGFRHIKEARTILKTRTIFNILGPLINPARPNKVVIGVYSKDLILPMAKTLVNLGIDRAVVVYGSGLDEVAIHDDTYVAEIQNNQIIEYKVSPVDFGIDTYAIKDLEGGLPEQNREIIKQILLGKGKEAHNAAVAVNVAMLMKLYDKDDLKQNTQEVLEIIKSGKCFNILQQVINYSNK
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: HUTI_BRASO
Sequence: MAQRFDRIWQNARLATLGEGRPGLGVIEHGVVASRAGRIAFAGPQSDFAADADAPERIDCEGRWITPGLIDCHTHLVYGGDRAHEFELRLAGASYEEIARAGGGIVSTVAATRAASEAELIASALPRLDALLAEGVTTIEIKSGYGLETATELRQLSAARALGEQRPVSVRTSFLGAHALPVEAGGDKERYIDLVCNEMLPAVAQSGAADAVDAFMETIAFSPEQTSRVFAAAKTLGLPVKLHADQLSNLGGAALAAGFGALSADHLEHTDEVGAVAMARSGTVAVLLPGAYYFIRETQKPPVELFRKHGVKLALATDCNPGSSPLTSLLLTMNMAATLFRMTVDECIAGVTREGARALGLLADTGTLEPGKWCNLAIWDIGRPAELVYRLGFNPLHQRVWRGR
What is the function of this protein?
Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate.  It is the third step in the universal histidine degradation pathway.
What are the official names of this protein?
Imidazolonepropionase, Imidazolone-5-propionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. HutI family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_CITBB
Sequence: MKVRASVKKICVKCKIVKRKGIVRVICETPKHSQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: MNMA_BORBR
Sequence: MPSNPTRKGRVVVGMSGGVDSSVTAWLLKQQGYEVVGLFMKNWEDDDDSEYCSTRQDLLDAASVADLVGVEFEYVNFAAEYKDRVFAEFLREYSAGRTPNPDVLCNAEIKFKAFLDHAMALGAEHIATGHYARVRTVETPAGPRHQLLKALDDTKDQSYFLHRLNQVQLARTLFPLGELRKTEVRRIAHEIGLHNAAKKDSTGICFIGERPFREFLNRYLPSEPGPILTPEGQRVGTHHGLSFYTLGQRKGLGVGGVKGRQRDDGTAEAWYAARKDLARNVLYVVQGHDHPWLLSAQLQAQDASWIAGEPPAAGAYGAKTRYRQADAACRLDQAGGERFALAFEQAQWAVTPGQSAVLYDGEVCLGGGIII
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PARI_HUMAN
Sequence: MAVFNQKSVSDMIKEFRKNWRALCNSERTTLCGADSMLLALQLSMAENNKQHSGEFTVSLSDVLLTWKYLLHEKLNLPVENMDVTDHYEDVRKIYDDFLKNSNMLDLIDVYQKCRALTSNCENYNTVSPSQLLDFLSGKQYAVGDETDLSIPTSPTSKYNRDNEKVQLLARKIIFSYLNLLVNSKNDLAVAYILNIPDRGLGREAFTDLKHAAREKQMSIFLVATSFIRTIELGGKGYAPPPSDPLRTHVKGLSNFINFIDKLDEILGEIPNPSIAGGQILSVIKMQLIKGQNSRDPFCKAIEEVAQDLDLRIKNIINSQEGVVALSTTDISPARPKSHAINHGTAYCGRDTVKALLVLLDEEAANAPTKNKAELLYDEENTIHHHGTSILTLFRSPTQVNNSIKPLRERICVSMQEKKIKMKQTLIRSQFACTYKDDYMISKDNWNNVNLASKPLCVLYMENDLSEGVNPSVGRSTIGTSFGNVHLDRSKNEKVSRKSTSQTGNKSSKRKQVDLDGENILCDNRNEPPQHKNAKIPKKSNDSQNRLYGKLAKVAKSNKCTAKDKLISGQAKLTQFFRL
What is the function of this protein?
Required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability.  Antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure.  Binds single-strand DNA and poly(A) homopolymers.  Positively regulate the poly(ADP-ribosyl)ation activity of PARP1; however such function may be indirect.
What are the official names of this protein?
PCNA-interacting partner, PARI, PARP-1 binding protein, PARP1-binding protein, PARPBP.
What is the protein family that this protein belongs to?
Belongs to the PARI family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Localizes to chromatin in response to S phase arrest but not in mitosis. Targeted to chromatin via its interaction with PCNA.
Protein: CLPX_COLP3
Sequence: MTDIKSGGDNGKLLYCSFCGKSQHEVRKLIAGPSVFVCDECVELCNDIIREEISEISPKESKEALPSPIEIRESLDEYVIGQDHAKKVLAVAVYNHYKRLRNGDNHNGIELGKSNILLIGPTGSGKTLLAQTLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVVEQRNHTGTGIGFGAEVRGKDQEISLTDRLADVEPQDLVKYGLIPEFIGRLPVLATLRELDEAALIQILQEPKNALTKQFTALFDMENVELEFRSDALHAIARKAMDRKTGARGLRSIVEAVLLDTMYELPSMENVSKIVVDENTIKGESKPIVIYDSKQEQAASE
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RL28_PARDP
Sequence: MSRVCELTGKGPMSGNNVSHANNKTRRRFLPNLNEVSLLSEKLGRSYQLRISAAALRSVDHRGGLDAFLAKAKDAELSDRALKIKRELAKA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: KDSA_CITK8
Sequence: MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKVITDVHEASQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFHEGGNDKVILCDRGANFGYDNLVVDMLGFSVMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVTELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQIKAIDDLVKSFGELDTEH
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PIP_LEVBA
Sequence: MDIQEEYMPFRAYQTYYRVVGDLRSPLTPLLLLHGGPGSTHNYFEAFDQLAMATGRPIVMYDQLGCGRSSIPTDPHLWQAATWVAELRALRAYLKLDCVHLLGQSWGGMLALIYLCDDQPRGIQSVILASTLSSAHLWAREQHRLIQFMSTTDQAAIHQAEMTGDFTTPAYLAANERFMIQHATGPITEQTPEFLRRSKRLGTAAYTTAWGPNEYFPTGTLRDYDYTAKLAQLPYPTLVTSGVNDLCTPLVAKTMVDQLPHAEWTLFPHSRHMAFIDEPAAYQARLTQWLAAHDEVTDD
What is the function of this protein?
Releases the N-terminal proline from various substrates.
What are the official names of this protein?
Proline iminopeptidase, PIP, Prolyl aminopeptidase, PAP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S33 family.
What are the subcellular locations of this protein?
Cell envelope.
Protein: PRO_ADE02
Sequence: MGSSEQELKAIVKDLGCGPYFLGTYDKRFPGFVSPHKLACAIVNTAGRETGGVHWMAFAWNPRSKTCYLFEPFGFSDQRLKQVYQFEYESLLRRSAIASSPDRCITLEKSTQSVQGPNSAACGLFCCMFLHAFANWPQTPMDHNPTMNLITGVPNSMLNSPQVQPTLRRNQEQLYSFLERHSPYFRSHSAQIRSATSFCHLKNM
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: SECA_SHEON
Sequence: MFGKLLTKVFGSRNDRTLKGLQKVVNKINALEADYEKLTDEQLKAKTAEFRERLAAGASLDSIMAEAFATVREASKRVFEMRHFDVQLLGGMVLDSNRIAEMRTGEGKTLTATLPAYLNALTGKGVHVITVNDYLARRDAENNRPLFEFLGLTVGINVAGLGQQDKKDAYNADITYGTNNEFGFDYLRDNMAFSPQERVQRPLHYALIDEVDSILIDEARTPLIISGAAEDSSELYIKINTLIPNLIRQDKEDSEEYVGEGDYTIDEKAKQVHFTERGQEKVENLLIERGMLAEGDSLYSAANISLLHHVNAALRAHTLFERDVDYIVQDGEVIIVDEHTGRTMPGRRWSEGLHQAVEAKEGVRIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFQHIYGLDTVVVPTNRPMVRKDMADLVYLTANEKYQAIIKDIKDCRERGQPVLVGTVSIEQSELLARLMVKEKIPHQVLNAKFHEKEAEIVAQAGRTGAVTIATNMAGRGTDIVLGGNWNMEIDALENPTPEQKAKIKADWQLRHDAVVAAGGLHILGTERHESRRIDNQLRGRAGRQGDAGSSRFYLSMEDSLMRIFASDRVSGMMKKLGMEEGEAIEHPWVSRAIENAQRKVEARNFDIRKQLLEFDDVANDQRQVVYAQRNELMDAESIADTIQNIQDDVISAVIDQYIPPQSVEELWDVPGLEQRLHQEFMLKLPIQEWLDKEDDLHEESLRERIITSWSDAYKAKEEMVGASVLRQFEKAVMLQTLDGLWKEHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFQQLLNTLKHDVISVLSKVQVQAQSDVEEMEARRREEDAKIQRDYQHAAAEALVGGSDEDDAIAAHTPMIRDGDKVGRNDPCPCGSGRKYKQCHGKLS
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: CP51_MIMIV
Sequence: MLFELSIGAIIGFLTLYLLKRFNESKNFITPDNLKKIPIVEGAVPVLGHGPAFSKDIMQFMKNCYKKYGSVFQLKIFRTNMVVLCDRKLSEEFFKSRENDMSLYDVLNRLFFGLAFSDKPDSLEFIIKMVKKTITIRYDDFAPKIMDEAQRLTKIMRESHSGKKLDMIPEIIKFVSRTSARCFIAMDIDDEFYDALNKFTNLLNKIVVLTYFVPHWLLNATLNRFMLRKYRMRMTKLLENEIEKYRTDLNKSDSLLFRKCVDHIDPETGATLTNQDIGDIVVCLLYVSSENTSLLATNCLIDLTLNPKYWDLIKSECSAMIALGDYKNLFKAPLLNSIVMESARLNSHVFALARKPKTVNRIGDYFVADNVDTISLCEPALMKFEIASDVYANPNSYDPVRFMAPRNEPKDSGHVMNWGKGVHECPGKQFAIYEVKAAIAYIVTNFERFEFNHNDLKINYFSPSAMCEKNISVEFIPSQQNIHNIVYKDRTYIVEHIKCNETSAWLIYNALDRQQQREYYQYTYEISTDSQEHKLIEKAGPHKPFPIAYDKLVYTGQSNCMTPTKWYDFASDIWELLTENYAELGFPIYDDKIRNFVPNSFYGQLYSVESIMPTHRDQHVDYGLSISIGSNCEFVIEDKTILLPSGSVLIGDFSKISHSVSKIFHEKPDHLSDFEFFNRVRFSAQIRSIDPDVQPLMTTQEFLDMISEY
What is the function of this protein?
Catalyzes the 14-alpha demethylation of obtusifoliol to 4 alpha-methyl-5 alpha-ergosta-8,14,24(28)-trien-3 beta-ol.
What are the official names of this protein?
Probable lanosterol 14-alpha demethylase, CYPLI, Cytochrome P450 51, Cytochrome P450-14DM, Cytochrome P450-LIA1, Sterol 14-alpha demethylase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane.
Protein: FTSZ_HELPY
Sequence: MVHQSEMENYNIGQASIEEVSDPAYKGAKIVVIGVGGGGSNMIKHLVEYGVHQDVTPIATNTDGQHLKNNPAPVKILLGKESTGGLGAGGIPDIGRKAAEESANEIKEAIKDAKLVIISTGLGGGTGTGATPTIVKIAKEVGALTIAIVTKPFKYEGNQKRKRAEEGLKELEQSSDSILVIPNDKILLTMKKNASTTECYREVDDVLVRAVSGISTIITKPGNINVDFADLKSALGFKGFALMGIGEATGEESAKLAVQNAIQSPLLDDASIEGAKSIIVFFEHHPDYPMMAYSQACDFIQDQAHQDVDVKFGQHTSDNIPIDHVRVTIIATGAERNSGGASLESIATPSQPVVKQTRKVGNGEYLKIPTEEELSIPTTMRIQQD
What is the function of this protein?
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site.  The regulation of the ring assembly controls the timing and the location of cell division.  One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells.  Binds GTP and shows GTPase activity.
What are the official names of this protein?
Cell division protein FtsZ.
What is the protein family that this protein belongs to?
Belongs to the FtsZ family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Assembles at midcell at the inner surface of the cytoplasmic membrane.
Protein: IF6_TRYCR
Sequence: GTTFRTSIAENALVGSYAVVNNKGCMVHPKTPAQDMDEIASLLQVPVVAGTINRGNAAIGSGLVVNDWAAFCGLNTTATEITVVERIFQLRRDLGGGRANLLQQLRDTLVDELA
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  May also be involved in ribosome biogenesis (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: RPOC_STAAM
Sequence: MIDVNNFHYMKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFGPTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIPSRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFRDYYDKYPGQFVAKMGAEGIKDLLEEIDLDEELKLLRDELESATGQRLTRAIKRLEVVESFRNSGNKPSWMILDVLPIIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSVIAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDVLEEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHVPLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFNNTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEEQNKKILATSVGKIIFNEIIPDSFAYINEPTQENLERKTPNRYFIDPTTLGEGGLKEYFENEELIEPFNKKFLGNIIAEVFNRFSITDTSMMLDRMKDLGFKFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQFNRGLITEEERYNAVVEIWTDAKDQIQGELMQSLDKTNPIFMMSDSGARGNASNFTQLAGMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRRLVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEIIIRPDELITPEIAKKITDAGIEQMYIRSAFTCNARHGVCEKCYGKNLATGEKVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEARNPKGQAVITEIEGVVEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEIGQPVQRGEVLTEGSIEPKNYLSVAGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSLVDIHNFTDANREAFKHRKRPATAKPVLLGITKASLETESFLSAASFQETTRVLTDAAIKGKRDDLLGLKENVIIGKLIPAGTGMRRYSDVKYEKTAKPVAEVESQTEVTE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: Y1245_BRUA4
Sequence: MLYYALVFLVVALVAGALGFGGIAGASAGIAQILFFVFLALLVISLIASAIRKA
What are the official names of this protein?
UPF0391 membrane protein Oant_1245.
What is the protein family that this protein belongs to?
Belongs to the UPF0391 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CG121_PHANO
Sequence: MAHVRTFTLPHYEAYPVHVALFKDVKNPSYLKSQLLEANPAFDYAFLDAAMVARLGIAWWSHAAANDRPQILSPTHLLSTTFITIHALCTHRQKTRTPHSELVFRLSPNNNIGESYKKFGISDTTTHLIAVKLPLKSSDAEAKEWLVDGEITNESVSQHLGSVVEGTSVEISEKGEELGQWCDIDKIRKVYKLGDGSAKKGKKGAAVNGDGAEKEGEKKQMEVVILGTIALKS
What is the function of this protein?
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.  CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex.  The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation.  The complex is required for efficient recruitment of transcriptional coactivators.  CGI121 is not required for tRNA modification (By similarity).
What are the official names of this protein?
EKC/KEOPS complex subunit CGI121.
What is the protein family that this protein belongs to?
Belongs to the CGI121/TPRKB family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: SYY_STRPG
Sequence: MNIFEELKARGLVFQTTDEQALVKALTEGQVSYYTGYDPTADSLHLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKETVLEWSDKIKGQLSTFLDFENGDNKAELVNNYDWFSQISFIDFLRDVGKYFTVNYMMSKDSVKKRIETGISYTEFAYQIMQGYDFYELNDKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMTVPLITDSTGKKFGKSEGNAVWLDADKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDEIAEIETQFNAARHERLAQKILAREVVTLVHGEEAYKQALNITEQLFAGNIKNLSANELKQGLSNVPNYHVQSEDSLNLVDMLVTAGISPSKRQAREDVQNGAIYINGDRVQDLDYQLSNDDKTDDQLTVIRRGKKKYAVLTY
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WECG_YERPA
Sequence: MEPNTVIPKYNVRGFEIWGFRDMAQVLDHLLGSGPVKTGTLVAMNAEKLLKAEDDTALCELIKNAEYLYADGISMVRAIRRKYPQAELSRVAGADLWEALMQRAGQQGTPVFLVGGKPDVLAETEAKLRAQWNVNLVGSQDGYFTPEQREALFARIAASGAAIVTVAMGSPKQEIFMRDCRKFYPDALYMGVGGTYDVFTSHVKRAPKIWQNMGLEWLYRLLAQPSRIRRQLKLLKFVGYYYSGRL
What is the function of this protein?
Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in enterobacterial common antigen (ECA) synthesis.
What are the official names of this protein?
UDP-N-acetyl-D-mannosaminuronic acid transferase, UDP-ManNAcA transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 26 family.
Protein: SYD_SHEPA
Sequence: MRSHYCGDVNKSHVGQEVTLVGWVNRSRDLGGVVFLDLRDREGIVQVVYDPDLPEVFDVASTLRSEFCVQIKGLVRARPDSQINADMRTGEVEILGLELTILNSSAPLPINMDKNQHNTEEQRLKYRYLDLRRPEMADRIVFRSKVTSAVRRFLDGNGFLDIETPILTKATPEGARDYLVPSRTYKGQFFALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIETSFMTSAQVMDKTEEMVRGLFKELLNVDLGEFPKMTFEEAMRRFGSDKPDLRNPLELIDVADIVKEVEFAVFNGPANDPEGRVAVLSIPGGAKLSRKQLDEYAKYVTIYGAKGLAWMKVNDLAQGMEGIQSPVLKFLSEDVVNALLERTGAQTGDLILFGADKANIVAEAMGALRLKAGEDFDLLQGEWKPLWVVDFPMFERTSDGGLHAMHHPFTAPSNMTPEELEANPIGAISDAYDMVLNGCELGGGSVRIHDSKMQSAVFRILGINDEEASEKFGFLLEALRYGTPPHAGLAFGLDRIIMLMTGASSIRDVMAFPKTTTAACPLTNAPGFANPVQLAELGVSVVEAEPKADAKDTE
What is the function of this protein?
Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
What are the official names of this protein?
Aspartate--tRNA ligase, Aspartyl-tRNA synthetase, AspRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_XYLFA
Sequence: MARIAGVNLAIQKHVWIGLQSIYGIGRTRSRKVCDAANVAIYTKIRDLSEPEIERLRVEVGKYVIEGDLRREVGMAIKRLMDLNCYRGLRHRRGLPLRGQRTRTNARTRKGPRKAIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: NADC_RAT
Sequence: MDPEGLQFLLPPASLAALANSWLQEDCPGLNFASLVTGSAPAQAVLWAKSPGVLAGRPFFDAIFTQLNCQVSWLLPEGSKLVPVVKVAEVRGPAHHLLLGERVALNTLARCSGIASAAATAVEVATSTGWAGHVAGTRKTTPGFRLVEKYGLLVGGAECHRYDLGGLVMVKDNHVVAAGSMEKAVLKARQAAGFPLKVEVECSSLKEALQAAEAGADLVMLDNFKPEELHPTAATLKAKFPNVSVEASGGVTLDNLPQFCGTNIDVISLGMLTQAAPALDFSLKLYAEGDIPVPHARRS
What is the function of this protein?
Involved in the catabolism of quinolinic acid (QA).
What are the official names of this protein?
Nicotinate-nucleotide pyrophosphorylase [carboxylating], Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase, QPRTase.
What is the protein family that this protein belongs to?
Belongs to the NadC/ModD family.
Protein: STU1_EMENI
Sequence: MDYKARDILSVLKNVNLSVDAKVTHLLGLKSDIKQKNVPEKAVPVIFECLRHAIASPFHALYSAGFSTLGHFLKRLYIQEHHQLVAAMSDRILPTLVDRMGDNKDRIRQQTTHALADLWEGAGPQIENLVLSVGFQGKNPFQKQTCLNLLSIAFTRSEITAAYAEATAKEYLPQIISFVEDADPTVRQGARALLVQMFIGERDSSKHELKRALEQYKVRPSHAREILAGIGLDPELYDESHSSRQHSIQQRAPSRAATASRAPSRAGISRAPSRAAISRAASRADISRAPSRADTFDERSGSTTTHVDSSSAADDGAPVLHHPKPVRTSPVTGGMIAASDNRIAVTDSIPANDFDSPKQKNTLRTNASKASGMVNAPAGHAAAPSALGHAVEKAKRAVEPLDIEPYDLSSSQELDRLQATMAPWFEGRETEMNFQRREEYTILIRRITHGNAPQRWPTAYLGFVKMTLPFVFITANSVRTSLQTAGLRAVQSLARVNKERLDSSIHIVLQNVLKLCANAKGITSQNSNLTIVAILENVTCNQRVLNQITGAAKDKNQNMRIFSAGWLEIIIDGQNRHKTHAEGVNSIAACIQEGVEDAKEDIRRAYRHTFFRFSSVWPARAKKILDAVSPKTQKLIEKDMLKMSEDPFVSNSGSSATGLFSSTPARAAAKGVTTEKGKASIAVPKAMSSPKLASRSTQPVTTKTNTLQKKPTSTLSSAPMRPGAAKPRPATAAGFQLKKKENESPRKKQTPSRVPEPGLDTPITRRRQNSDPTQNESPTKSGWVAHAADDHHIGPLTIPKRRSTRDTETPRAKASKQADIEVEMDDKNYDGRADEIVQEKVNETVYETVDEMVDERANERVDEYFDEHVDERIDEMVREKVDEKVDEEVDEKVDEKVDEKVDEKVDEKADEKVDEKVDEKVNEKVDSAADDNLQEEVAEKRSMSLSDEIIASAQRPSDEVKERSSEAERASMGKGGSPRPEREYVDSTIVSESPLPKRAVSLWSQNSINAHGILLKGIERIQTRTMATDGYRKLQGLIQHHPDLFADEEQFAVLLIGLLDELAEQTPPSKSVLSLGTVSDHKTQVLFTVKYMFENFKKFFAPHYPGTVVALLEAEKSAEMGGHLIKAIENFIDDIVNASRAHYEIIGAVVTHLGPAVQNEAGPTEHRMLRKGLDVITHGLTSMKEREWELPPDQLERLGEFVRQVMTLPSVALKRRIFALCIALRELVDNEERFWELVGSKTKGVDGLLFYYRTRQEAQAA
What is the function of this protein?
Microtubule binding protein that promotes the stabilization of dynamic microtubules.  Required for mitotic spindle formation (By similarity).
What are the official names of this protein?
Protein stu1.
What is the protein family that this protein belongs to?
Belongs to the CLASP family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle.
Protein: RL32_PROM5
Sequence: MAVPKKKKSKSKRNHRHAVWKGKAALAAQKAISLGKSVLTGKAQGFVYPIDEEEESEE
What are the official names of this protein?
50S ribosomal protein L32.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
Protein: CYAY_BURM1
Sequence: MSDTEYLTRAEAVLAAVERTVDAANDGDHDIDLERNGSVLTLTFENGSKIIVNLQPPMKEVWIAAKAGGFHYRYVDGAWRDTRTGTEFFAALSEYATQQAGLPITFTA
What is the function of this protein?
Involved in iron-sulfur (Fe-S) cluster assembly.  May act as a regulator of Fe-S biogenesis.
What are the official names of this protein?
Iron-sulfur cluster assembly protein CyaY.
What is the protein family that this protein belongs to?
Belongs to the frataxin family.
Protein: RL10_KORVE
Sequence: MAVTKAKKIEVTEKLTEDFKKANHAIVGTFNKLTVSKDYELRKAVRSVGGKYSVVKNTLAERAAKGTKIEDAVKGLAGVTSVAFTDGDPVQLAKVLSKYAKDNPEYEFKAGVVDGKVIKLADIDALANMPSKEELYSKLLFLISAPAQRLVTVMNATGRDLAVVLNQGVEKQKFSGGEAPAQ
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.