PharMolix/UniProtQA huggingface dataset:
Protein: PLE4_PSEAM
Sequence: MKFTATFLMMFIFVLMVEPGECGWGSIFKHGRHAAKHIGHAAVNHYLGEQQDLDKRAVDEDPNVIVFE
What is the function of this protein?
Antimicrobial peptide.
What are the official names of this protein?
Pleurocidin-like peptide WF4.
What is the protein family that this protein belongs to?
Belongs to the pleurocidin family.
What are the subcellular locations of this protein?
Secreted.
Protein: DEF1_VIBVU
Sequence: MSVLQVLTFPDDRLRTVAKPVEKVTPEIQKIVDDMIETMYDEEGIGLAATQVDIHQRIVVIDISESRNEPMVLINPEILEKRGEDGIEEGCLSVPGARALVPRAAEVTVKALDRDGHEFTLEADDLLAICIQHELDHLQGKLFVDYLSPLKRKRIQDKLAKIKRFNEKQR
What is the function of this protein?
Removes the formyl group from the N-terminal Met of newly synthesized proteins.  Requires at least a dipeptide for an efficient rate of reaction.  N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
What are the official names of this protein?
Peptide deformylase 1, PDF 1, Polypeptide deformylase 1.
What is the protein family that this protein belongs to?
Belongs to the polypeptide deformylase family.
Protein: QUEF_HELPJ
Sequence: MTPESNLKSLGAKTPYIFEYNSDLLEAFPNPNPNLDPLITLECKEFTSLCPITSQPDFGVIFIRYIPKDKMVESKSLKLYLFSYRNHGSFHESCINTILLDLVQLLEPKYLEVYGDFVSRGGIAIKPFVNYAIKEYQDFKEKRLLDAK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPMA_YERP3
Sequence: MAVTKLVLVRHGESQWNNENRFTGWYDVDLSEKGRSEAKAAGKLLKDEGFTFDFAYTSVLKRAIHTLWNILDELDQAWLPTEKTWKLNERHYGALQGLNKSETAEKYGDEQVKQWRRGFAITPPALEKSDERFPGHDPRYAKLTDAELPTTESLALTIERVIPYWNDVIKPRIASGERVIIAAHGNSLRALVKYLDDLGEDEILELNIPTGVPLVYEFDENFKPIKHYYLGNADEIAAKAAAVANQGKAK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: AROB_SALTY
Sequence: MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELTSGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLAIGKSEVRGGVSHEVVLSAIADCQQA
What is the function of this protein?
Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
What are the official names of this protein?
3-dehydroquinate synthase, DHQS.
What is the protein family that this protein belongs to?
Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMF_SHEFN
Sequence: MAQLNTNFINHIEKELPAHLSLQEFIAYCDKPLRKSIRVNTLKISTAQFVHIMTSAGWQLSPVPWCADGFWIEGKDDIQLGNAIEHIQGLFYIQEASSMLPPTALFSNDNTAEIVLDVASAPGSKATQIAALMNNSGLLVANEYSASRVKVLHANVLRMGASHTALTHFDGRVYGEYLYESFDAILLDAPCGGEGTVRKDPLALKHWDIDDVTAIGETQKDLIESAFLALKPGGILVYSTCTLSQLENQHICYHLQQTYPDAVEFESLAELFDGADKACTEEGFLHVWPQIYDSEGFFVAKIRKKASVERVKKQPKLQKNFPFNPANEKQKAELTQYFYDSFCLELPSDDVIMLRDDEYWLFPAQFMPFIGKMRFQRIGIKLADAMKKGYKAKHEAVIALSAATHNPAKTMELSAAQAQDFLMGRDIATSTFDQPTQQQLAIMPQGEMLVSYHKVVLGVVKHLGHRLKNNLPRDLVRDNVNLYL
What is the function of this protein?
Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase F, 16S rRNA m5C1407 methyltransferase, rRNA (cytosine-C(5)-)-methyltransferase RsmF.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESXB_STAAW
Sequence: MGGYKGIKADGGKVDQAKQLAAKTAKDIEACQKQTQQLAEYIEGSDWEGQFANKVKDVLLIMAKFQEELVQPIADHQKAIDNLSQNLAKYDTLSIKQGLDRVNP
What is the function of this protein?
Virulence factor that is important for the establishment of infection in the host.  EsxB is required for EsxA synthesis as well as secretion (By similarity).  Mediates together with EsxA the release of S. aureus from the host cell.  Inhibits also host cytokine production and thus modulates dendritic cell-mediated immunity (By similarity).
What are the official names of this protein?
Type VII secretion system extracellular protein B, Ess extracellular protein B.
What is the protein family that this protein belongs to?
Belongs to the WXG100 family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESAT-6 secretion system (Ess) / type VII secretion system (T7SS).
Protein: PACMP_HUMAN
Sequence: MAASGGTKKAQSGGRRLREPSSRPSRRARQRPRRGALRKAGRFL
What is the function of this protein?
Micropeptide that acts as a regulator of DNA repair both by preventing KLHL15-mediated ubiquitination and degradation of RBBP8/CtIP, and by promoting the poly-ADP-ribosyltransferase activity of PARP1 (PubMed:35219381).  Prevents KLHL15-mediated ubiquitination of RBBP8/CtIP by competitively blocking the association between KLHL15 and RBBP8/CtIP (PubMed:35219381).  Recruited to DNA damage sites via association with poly-ADP-ribose chains, and enhances the poly-ADP-ribosyltransferase activity of PARP1 (PubMed:35219381).
What are the official names of this protein?
Poly-ADP-ribosylation-amplifying and CtIP-maintaining micropeptide, PAR-amplifying and CtIP-maintaining micropeptide.
Protein: Y857_METJA
Sequence: MPKTIKLTKTIALKSKPLTKTKIKIIENTIESYKEVLSIALDFGLKNNRKSHRKIREGIYEEIKSKLPKLPTHYIYTASQDASTRIKSFIAMKKRDKAYTSKPKIKNISLWLDDVLTNYRDFKNNIEKLFLIDKEGKKTLHLRLSTPNGRIVIPLKPHKQFFKLLNEGWGIKAGFKLRLNKEDGTITVLIPLEKEITINDSYKTVYALDFNLDNITYGNFENIELIKTDLGKLTEKYSNIMTNIQEKFSFKGIHKQDKPLKRKGFILLKNSVGG
What are the official names of this protein?
Uncharacterized protein MJ0857.
Protein: CYSG_ACTPJ
Sequence: MNYLPIFVDLKNRPVLVVGGGHIAVRKIDALLKAGASVKVVAEKLHSSLQSLTDEGKVEWIAKTFEANQVTNSYLVIAATDDNALNQLVFETAESQQRLVNVVDDQPRCSYIFPSIIDRSPVQIAISSGGAAPVLIRLLREKLEALIPPNLGAMADIATRWRSAVKTQFPQLTQRRRFWEKLFTHQSFQRLTENHQIEQAEALVEAELHNNNPVLGEVSLVGAGPGDAGLLTLKGLQTIQQADVVLYDALVSEAVLELVRRDADKVFVGKLAGKHSVKQEDTNQLLVKYAKQGKRVVRLKGGDPFVFGRGGEELEILKAENIPFSIVPGITAALGATAYAGIPLTHRDHAQTAMFITGHLKPDGNRLKWETLAQGNQTLVVYMGTIKAAELSAELQKHGKPSDTPVAIISNGTLPNQQVQTGVLSELAELAEKAPTPALIVIGEVVKLQKDLAWFGKEAVQFVSTQETLWQKPTLQNKETHWKQAA
What is the function of this protein?
Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1.  Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin.  Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
What are the official names of this protein?
Siroheme synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the precorrin methyltransferase family.
Protein: BUK_CLOP1
Sequence: MAYKLLIINPGSTSTKIGVYEGEKEILEETLRHSAEEILKYDTIFDQLDFRKEVILKVLKEKGIDINELDAVVGRGGMLKPIEGGTYEVNEAMVEDLKIGVQGPHASNLGGILSNEIAKEIGKRAFIVDPVVVDEMEDVARLSGVPELPRKSKFHALNQKAVAKRYAKEHNTSYEDVNLIVVHMGGGVSVGAHRKGRVIDVNNALDGDGPFSPERAGGVPSGELLEMCFSGKYSKEEVYKKLVGKGGFVAYANTNDARDLIKLSQEGDEKGSLIFNAFIYQIAKEIGSMAVVLDGEVDAIVLTGGIAYSDYVTNAINKKVKWIAPMVVYGGEDELLALAQGAIRVLDGVEEAKIYK
What is the function of this protein?
Catalyzes the conversion of butyryl-CoA through butyryl phosphate to butyrate.
What are the official names of this protein?
Butyrate kinase, BK.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPD_CHLTE
Sequence: MRQQEILQKLLEGHDLSRQEMETCMNSIMENRFTDAGTGAILALLQKKGATPAEVIGACASIVSKSTPVTLDQQAVDTCGTGGDHTGTFNISTAAAFIACGAGIPIAKHGNRSITSKCGSADVLEALGYQVDLPPCATEELFRETGFAFLFAPLYHPSMKAVAAIRKELGIKTIFNMLGPIINPAGVRRQLIGVFDPSVMDIYAEVLLLNGCEHAMLVHGSTGNSMGLDEPSVCGPTSMIELHQGQIIRHTVEPEDFGLGRWDIGELAGGDSHVNAQIIREILDGSAPQAKIDAALFASAITCYVSGKASCIDEGMSLSKGSLETCEALDKMNLIIKTNQRLAQKCASATN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: PUR5_METSB
Sequence: MTDETKLTYADAGVDIDAGNAMVEAIKPLVRATRRRGADAEIGGFGGLFDLKAAGFTDPILVAANDGVGTKVRIAIETGAHDTIGIDLVAMCVNDLIVQGAEPLFFLDYYASGKLDGAAAAAVVKGIANGCIEAGAALIGGETAEMPGLYAGADYDLAGFAVGAVERGALLPRSDIAAGDVLLGLASSGAHSNGFSLIRKIVAAQKLGWDAPAPYAPGQSLGAALLTPTRIYVKTLLPLLRAQAGIKGLAHITGGGFPDNLPRVLPQGLGVEVDLSAIAVPPVFAWLAEAGHVSAAEMLRTFNCGVGMALICAEADAGALLASLRAAGEQPVALGRVTPAGAERVTYSGRLSL
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL18A_METJA
Sequence: MAKIFRITGIMSKKGKDPLYFRKEYKALKPEDALEILYSEFGGRYKVKRSRIKILNIEEIKPEDVTDPVLKKLVTA
What are the official names of this protein?
50S ribosomal protein L18Ae, 50S ribosomal protein L20e, 50S ribosomal protein LX.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
Protein: LSPA_BORDL
Sequence: MNINRNRLVSNLIFISILVFFDQWSKYLVVTYVRLGTEYLSFFGDLFKIIHVRNTGVLFSLGSNIDSSLKNLFFLIIPIIILVFVFSFSLKENNKVSRFALILILSGGIGNIIDRLFRPLGVVDFLDVKFFGIFGLQRWPTFNFADSYVVVGMIVFIIYDLFTKDKSTNL
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS10_LISMC
Sequence: MAKQKIRIRLKAYDHRILDQSAEKIVETAKRSGASVSGPIPLPTEKSIYTVLRAVHKYKDSREQFEMRTHKRLIDIVNPTPQTVDSLMRLDLPSGVDIEIKL
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RF1_AMOA5
Sequence: MIDKLEAIEKKYEEVSKQIVDPSIMADMKQYASLNKTYKELSKIVDVYTVYKSNLANLESAKTLLSIEKDAAFRDLAKEEIDSLELQKTQLEEDLKFLLLPKDPNDSKNVILEIRAGTGGDEAGIFAGDLFRMYSRFAEKMQWKLSIIEEVESTSGGYKEIICSIAGEGAYGMLKYESGVHRVQRVPATETQGRIHTSAASVVVLPEMDEVEVDLDMNDIRKDTFCSSGPGGQSVNTTYSAIRLTHIPTGIVVSCQDEKSQIKNLEKALKVLRARLYEQELKKQQDAIGAERRSMVKSGDRSDKIRTYNFPQGRVTDHRIGYTIHNLPAVMDGAVGDLIEALQLADNAERLQQGA
What is the function of this protein?
Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
What are the official names of this protein?
Peptide chain release factor 1, RF-1.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SELU_ECOSE
Sequence: MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQRSHIVQSWLYAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQQQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAR
What is the function of this protein?
Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2-selenouridine (Se2U-RNA).  Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
What are the official names of this protein?
tRNA 2-selenouridine synthase.
What is the protein family that this protein belongs to?
Belongs to the SelU family.
Protein: GAL1_CLOAB
Sequence: MDIINMLDEKFKNIFKRHYENVFFSPGRVNLIGEHTDYNGGHVFPCALTIGTYGLVARRNDNKVLAYSLNFDNLGVIEFSLDDLKKCKKDDWANYVKGVIDTFNKHGHNIENGFEILFYGSIPNGSGLSSSASIEVLTGIILNDLFKLNINMVEIVKMCQEAENSFIGVNCGIMDQFSIGMGKKDCAILLDCSTLEYSYSKLNMTGYKIVIANTNKKRGLADSKYNERRSECEAALKELQKVKNINSLGELTEAEFEELKDIISDPVKLRRARHAVYENQRTLKAVVSLNNNDLKTFGKLMNESHISLRDDYEVTGIELDTLVSLALESKGVIGSRMTGAGFGGCTVSIVKEDYVDEFIESIKAKYTEKIGYEPSFYIVNIADGAKKIN
What is the function of this protein?
Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
What are the official names of this protein?
Galactokinase, Galactose kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. GalK subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HIS6_KORVE
Sequence: MLKRRIIACLDVRDGRVVKGVNFVNLRDAGSPAEMAGAHAKAGADEIVLLDITATYEGRGTLLETVRKTAAELFIPFTVGGGIRTLDDARAVFDCGADKLAINSAAIADPDLITKIAARFGSQAVVLAIDARRTGSRWEVFKTGGRTGTGLDAEQWAAEGEKRGAGEILLTSMDCDGTQTGFDCELTAAIASRVSIPVIASGGAGTAEHFVDVFQRGHADAALAASIFHFGVHDVNELKRTLSAAGIPVRLEC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL162_MIMIV
Sequence: MSNQLPIHDDLIVYMMQFLDDCSKRKFISTCRFLLELQSRIYYDDEVYVYNEVQHLSYSEFFKRLYYYAGIISSNINFIPQNIEYLQIYRDVSIEDLFEKNAEKLGSIKYLDIDEIDTGKINKLKNNPNSIKTLFVSNEQNILNLLIPSINKLYIHYHSNLDLNLSFSKLTRITFHIGFNKSTDFMFPESLEYLDLGDKFNTPLTPNSLPKNLKHLYLGYKYNYPIENCLPYGLKHLIFGHLFTQKIKNAIPETVTHLCMGGRFYRKVKGYLPKNLIHLEFGWGFNKPLLGEIPNVEYLKTGSSFEYPICDDSNPSKITHLIVGSKINKSDYVLPRNLKTLILDLDYDDPTILFKIPNSVTNLVIVNSTSIDLGSFDLNCYDHVTHLTLNTFVKGSLKYFHNVDTLILDQYFSTSLHNFLPNNLKHLYIENEIYKKQKQFIETNVIIHTFKSSWFSETEDKFLSKFWYGESKYDFIDKIIEYHKKYDNNKFIQKPLVESIIPIKQNSNHDCGLYCPFSKDY
What are the official names of this protein?
Putative FNIP repeat-containing protein L162.
Protein: ATPA_MESH2
Sequence: MNKDINIAAIIKNEIENFEGKIQNHDIGKVIIVGDGVALVSGIEKVKFGELVEFENNVLGIALNLEQDLIGVVIMASENSVFQGSIVRRTKSVISITVGDQLLGRVVNALGIPIDGKAELDNSLKSAIFTNAPSIMDRKSVDRGLKTGILAIDSLVPIGKGQRELIIGDRQTGKTTIAIDAILNQKGKNVYCVYVAIGQKNSSVAQIVSLLEKKGAFEYTTVILAGASELSPLQYLAPYSGAAIAEYWMNKKKDVLIIYDDLSKHAIAYRTLSLLLRRPPGREAFPGDIFYQHSYLLERSAQLSNDKGGGSITALPIIETQAGDISAYIPTNVISITDGQIFLRDSLFNSGQKPAIDIGLSVSRVGSAAQTNLMKWASSSLKLNLAQYNELKAFAQFGSDLGPSSQLILDRGNKIYEILKQENQYPLTERQQIMLLILIRENLIDSLEQKSIPLFKSAFLKYCDSEPKFRDKIEKMDYNRVLEPNNLAGILKDITDFIEKFNLGNVF
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: GCH1_BACC1
Sequence: MAKVNLEQIEHAVRLILEAIGDDPNREGVLDTPKRVAKMYAEVFSGMHEDPKEHLHKVFGEDHEELVLVKDIPFYSMCEHHLVPFYGVAHVAYIPQGGKVTGLSKLARTVDTIARRPQLQERITSTVANSIMEVLEPHGVMVVVEAEHMCMTMRGVKKPGAKTVTTAVRGVLENDAAARSEILSFIKTK
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: PTH2_MOUSE
Sequence: MLSKFLTMEYLVHPGTLSLAAGVACGMCLGWGLRSHLGMFPQNSTSEANRDTETGTEASILGESGEYKMILVVRTDLKMGKGKVAAQCSHAAVSAYKQTQRRSPQVLKEWEYCGQPKVVVKAPDEDTLIQLLTHAKTLGLTVSLIQDAGRTQIEPGSRTVLGIGPGPVELIDEVTGHLKLY
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase 2, mitochondrial, PTH 2.
What is the protein family that this protein belongs to?
Belongs to the PTH2 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RIMM_BACTN
Sequence: MIKKEEVYKIGLFNKPHGIHGELQFTFTDDIFDRVDCDYLICLLDGIFVPFFIEEYRFRSDSTALVKLEGIDTAERARMFTNVEVYFPVKHAEEAEDGELSWNFFVGFRMEDVRHGELGEVVEVDTATVNTLFVVEQEDGEELLVPAQEEFIVEINQEKKLITVELPEGLLNLEDLEED
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROB_BURM9
Sequence: MRSIIADSKRLVVKVGSSLVTNDGRGLDHDAIGRWAAQIAALRGAGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFAEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDTLVILTDQPGLFTADPRKDPGATLVAEASAGAPELEAMAGGAGSSIGRGGMLTKILAAKRAAHSGANTVIASGRERDVLVRLAAGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVDKLTAGGKSLLPIGVVAVQGVFARGEVIACVDDTGREVARGITNYSSAETKLIQRKPSGEIETVLGYMLEPELIHRDNLVLV
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GM4D_YERE8
Sequence: MKKALITGITGQDGSYLAEFLLEKGYQVHGIKRRSSSFNTSRIDHIYQDPHEVNPHFFLHYGDLTDTSNLIRLVKEIQPDEIYNLGAQSHVAVSFESPEYTADVDAMGTLRLLEAVRINGLEHKTRFYQASTSELYGLVQEIPQRETTPFYPRSPYAVAKMYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIALGLEDCLYLGNMDSLRDWGHAKDYVRMQWMMLQQDQPEDFVIATGKQITVREFVRMSAKEAGIEIEFSGKGIDEIATISAISDEYATSAKVGDIIVRVDPRYFRPAEVETLLGDPSKAKEKLGWVPEITVEEMCAEMVAGDLQQAKQHALLKANGFDVSITLES
What is the function of this protein?
Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
What are the official names of this protein?
GDP-mannose 4,6-dehydratase, GDP-D-mannose dehydratase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
Protein: SYE_LACLA
Sequence: MNKKIRVRYAPSPTGLLHIGNARTALFNYLFARHHGGDFIIRIEDTDRERHVEDGERSQLENLRWLGMDWDESPETHENYRQSERLPLYQKYIDQLLTEGKAYYSYKTPEELEADHAKQEAAGIAPHYINEYAGMSDDEKAAYIAERKAQNIEPVVRISVDEKAIYKWNDIVKGDIEFEGKNIGGDWVIQKRDGYPTYNFAVVVDDHDMQISHVIRGDDHIANTPKQLVVYDALGWEAPQFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYMSDAIFNFIALLGWNPGGEKEIFSREELIELFDEHRLSKSPAAFDQKKLDWLDNEYIKNADFAKVFELTKPFLVAANRFDERAEELVKLYQPQMKSADEIVELTDLFYGDFPELTDEAREMLAAETTPLALSTFRAKLAELPENDFTVENIFPLFKATQKETGVKGKMLWMPIRIAASGSMHGPELPETIALLGKEKVLAHLDAALNK
What is the function of this protein?
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
What are the official names of this protein?
Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KUP_STRA5
Sequence: MQHVNHSSFDKASKAGFIIALGIVYGDIGTSPLYTMQSLVENQGGISSVTESFILGSISLIIWTLTLITTIKYVLVALKADNHHEGGIFSLYTLVRKMTPWLIVPAVIGGATLLSDGALTPAVTVTSAVEGLKVVPSLQHIFQNQSNVIFATLFILLLLFAIQRFGTGVIGKLFGPIMFIWFAFLGISGLLNSFAHPEVFKAINPYYGLKLLFSPENHKGIFILGSIFLATTGAEALYSDLGHVGRGNIHVSWPFVKVAIILSYCGQGAWILANKNAGNELNPFFASIPSQFTMHVVILATLAAIIASQALISGSFTLVSEAMRLKIFPQFRSTYPGDNIGQTYIPVINWFLFAITTSIVLLFKTSAHMEAAYGLAITITMLMTTILLSFFLIQKGVKRGLVLLMMIFFGILEGIFFLASAVKFMHGGYVVVIIAVAIIFIMTIWYKGSKIVSRYVKLLDLKDYIGQLDKLRHDHRYPIYHTNVVYLTNRMEEDMIDKSIMYSILDKRPKKAQVYWFVNIKVTDEPYTAEYKVDMMGTDFIVKVELYLGFKMRQTVSRYLRTIVEELLESGRLPKQGKTYSVRPDSNVGDFRFIVLDERFSSSQNLKPGERFVMLMKSSIKHWTATPIRWFGLQFSEVTTEVVPLIFTANRGLPIKEKSELTTTGD
What is the function of this protein?
Transport of potassium into the cell.  Likely operates as a K(+):H(+) symporter.
What are the official names of this protein?
Probable potassium transport system protein Kup.
What is the protein family that this protein belongs to?
Belongs to the HAK/KUP transporter (TC 2.A.72) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL10A_CAERE
Sequence: SGSIRLKHIPRPSMKVCVFGDQHHLDEAAAGNIPAMSADDLKKLNKQKKLIKKLAKSYDAFIASESLIKQIPRILGPGLNKAGKFPSVVTHGESLQSKSDEIRATVKFQMKK
What are the official names of this protein?
60S ribosomal protein L10a.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: H2A_ACRFO
Sequence: MSGRGKGKAQGTKSKSRSSRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKSRIIPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLPKKTEKKQH
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: PSB_METVM
Sequence: MDTMKGTTTVGLICDDAVILATDKRASMGNLIADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRALIAEARLYKMRTGKNISPRACATLLSNILHSSRMFPFLTQIIIGGYDLTDGPKLFSLDPLGGMNEEKTFTSTGSGSPIAYGVLEAEYDRDMSIEEGLKLALKALKSAMERDTYSGNGVSVAVITKEGVKLLSDEEITKLLGNDKSKTKKKSTRRRKKSK
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.