PharMolix/UniProtQA huggingface dataset:
Protein: BARA_ECO57
Sequence: MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYIALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG
What is the function of this protein?
Member of the two-component regulatory system UvrY/BarA involved in the regulation of carbon metabolism via the CsrA/CsrB regulatory system.  Phosphorylates UvrY, probably via a four-step phosphorelay (By similarity).
What are the official names of this protein?
Signal transduction histidine-protein kinase BarA.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RHOAA_DANRE
Sequence: MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDSKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELQKMKQEPVKPEEGRDMANRINAFGYLECSAKTKEGVREVFEMATRAALQAKKRGKKNACALL
What is the function of this protein?
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
What are the official names of this protein?
Rho-related GTP-binding protein RhoA-A.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: SCRK_STRMU
Sequence: MSKLYGSIEAGGTKFVCAVGDENFQILEKVQFPTTTPYETIEKTVAFFKKFEADLASVAIGSFGPIDIDQNSDTYGYITSTPKPNWANVDFVGLISKDFKIPFYFTTDVNSSAYGETIARSNVKSLVYYTIGTGIGAGTIQNGEFIGGMGHTEAGHVYMAPHPNDVHHGFVGTCPFHKGCLEGLAAGPSLEARTGIRGELIEQNSEVWDIQAYYIAQAAIQATVLYRPQVIVFGGGVMAQEHMLNRVREKFTSLLNDYLPVPDVKDYIVTPAVAENGSATLGNLALAKKIAAR
What are the official names of this protein?
Fructokinase.
What is the protein family that this protein belongs to?
Belongs to the ROK (NagC/XylR) family.
Protein: EST2E_RAT
Sequence: MAQTRAWKSIMPLESLPGWLNAVVWGLLLLFCQVQGQDSASPIRNTHTGQVRGSFVHVKDTKSGVHTFLGIPFAKPPIGPLRFAPPEPPEPWSGVRDGTSHPAMCLQNIDGLNLENLKIKMSRSPVSMSEDCLYLSIYTPAHTHKDSNLPVMVWIHGGGLCWGMASTYDGSMLAAIEDVVVVTIQYRLGILGFFSTGDEHARGNWGYLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGISVSSHVVSPMSQGLFHGAIMESGVALLPNLISNTSEVIYTMVANLSGCEPVDSEALMSCLREKSEEEMLAINNIVRTISGVVDGKFLPRHPLELLASVDFHPVPSIIGINSDEYGWIIPMLHPDSTMKEINRETMRAVLKNTAVQMMLPPECSDLLMEEYMGDTEDSKTLQIQFNEMMGDFIFVIPALQVAHFQRSHAPVYFYEFQHQSNFLKDIRPPHVKADHGDELPYVIGYLFWDMKFVFTEEEKLLSRKMIKYWANFARHGNPNSEGLPYWPALDHDEQYLQLDIQPVVGRALKARRLKFWTKTLPQKIQELKGSQDNHTEL
What is the function of this protein?
Carboxylesterase that catalyzes the hydrolysis of pyrethroids pesticides.  Hydrolyzes trans-permethrin at a rate about 22-fold higher than cis-permethrin.  Also hydrolyzes trans-cypermethrin (By similarity).  Hydrolyzes retinyl esters (PubMed:12230550).
What are the official names of this protein?
Pyrethroid hydrolase Ces2e, Carboxylic ester hydrolase.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Microsome.
Protein: RM47_BOVIN
Sequence: MAAASLAVFCRRVSAALKASTSLISSQTLASTGCRFSLSLLTKNTPNVTSFHQCRLLQTTLSRRGLEEFFDDPKNWGEEKVKSGASWTCQQLRNKSNEDLHKLWYVLLKERNMLLTLEQEAKRQRLPMPSPERLEKVVDSMDALDKVVQEREDALRLLQTGQEKPRPGAWRRDIFGRIIWHKFKQWPIPWYLNKRYNRKRFFAMPYVERFVRLRIEKQARIKARKISLTQKKEKFLQKKFPHLSEAQKSSAA
What are the official names of this protein?
39S ribosomal protein L47, mitochondrial, L47mt, MRP-L47.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL29 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RL31_GLOC7
Sequence: MPKADIHPTWYPEAKVICNGEVVMTVGSTQPEIHVEVWSGNHPFYTGTQKMIDTEGRVDRFLRKYGMIDKNKKKNQASDAKEK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: PSBT_CEDDE
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKGGK
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: BIOD_AFIC5
Sequence: MSTRLVVSGTDTDVGKTVFSAALAGALDADYWKPVQAGRDDGTDALRVARLSGLPPERILPERYILNTPASPHYAARIDGITIDTNDLTPPPAKDRPLVIEGAGGLMVPINEDTLFIDVFARWKLPLVLCARTTLGTINHSLLSIEAVKRRDIPLVGIAFIGEDYAESERIICKIGGVRHLGRLPPLSPLTPEALRAAFITSFNLSDFTA
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_GEOUR
Sequence: MSKEEAIEVEGTVIEPLPNAMFKVKLENDHIVLAHISGKMRKYFIKILPGDKVTVELSPYDLTRGRITYRAK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3591_METAC
Sequence: MLTETEGRVAVKLARKTIETLLLGGRVPGPRDAGTDLPPVFGENRGVFVTLTEKGMLRGCIGHPYPDSTLEQAIIDSAISAAVRDPRFPPVGGEELESLIVEVTILTQPEKINAPPKELPDKVEIGKHGLIVKQGYCQGLLLPQVAPENEMDSIDFLGHTCMKAGLSPDAWAKGAEVYCFEGQIFKEKEPEGEVIEEKF
What are the official names of this protein?
Protein MA_3591.
Protein: RS18_THIDA
Sequence: MGGKSGGKFAGKRRDSGNRGLFKRRKFCRFTAEKVVEVDYKDVDVLKEFIAENGRIIPARITGTKAHYQRQLGTAIKRARFLALMPYTDLH
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RS18_PSEAE
Sequence: MARFFRRRKFCRFTAEGVKEIDYKDLNTLKAYVSETGKIVPSRITGTKAKYQRQLATAIKRARYLALLPYTDSHGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: TX30_ANDCR
Sequence: MKIIFLVLMMILSEVYSDRDGYPVHDGTNCKYSCDIREKWEYCTPLCKRRNAKTGYCYAFACWCIGLPDEVKVYGDDGIFCKSG
What is the function of this protein?
Toxin with unknown target.  In vivo, induces severe neurotoxic events in mice such as excitability and convulsions, leading to the death of the animals within a few minutes after injection (PubMed:22819772).  Exerts very strong cytotoxic effect on a mouse brain tumor cell line (BC3H1) (IC(50)=5 mg/ml).  It exerts its effects by inducing a stronger necrosis than apoptosis in BC3H1 cells (PubMed:24055552).
What are the official names of this protein?
Toxin Acra3.
What is the protein family that this protein belongs to?
Belongs to the long (4 C-C) scorpion toxin superfamily. Sodium channel inhibitor family. Beta subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: GGAG_MLVMN
Sequence: LGDVPGTSGAVFVARPESKNPDRFGLFGAPPLEEGYVVLVGDENLKQFPPPSEFLLSVWNRSRAARLVCCSIVLCCLCLTVFLYLSENMGQTVTTPLSLTLDHWKDVERIAHNQSVDVKKRRWVTFCSAEWPTFNVGWPRDGTFNRDLITQVKIKVFSPGPHGHPDQVPYIVTWEALAFDPPPWAKPFVHPKPPPPLPPSAPSLPLEPPLSTPSRSSLYPALTPSLGAKPKPQVLSDSEGPLIDLLTEDPPPYRDPRPPPSDGDGNSGEATPAGEAPDPSPMASRLRGRREPPVADSTTSQAFPLRTGGNGQLQYWPFSSSDLYNWKNNNPSFSEDPGKLTALIESVLITHQPTWDDCQQLLGTLLTGEEKQRVLLEARKAVRGDDGRPTQLPNEVDAAFPLERPDWEYTTQAGRNHLVQYRQLLLAGLQNAGRSPTNLAKVKGITQGPNESPSAFLERLKEAYRRYTPYDPEDPGQETNVAMSFIWQSAPDIGRKLERLEDLKNKTLGDLVREAERIFNKRETPEEREERIRRETEEKEERRRTEDEQKEKERDRRRHREMSKLLATVVSGQRQDRQGGERRRSQLDRDQCAYCKEKGHWAKDCPKKPRGPRGPRPQTSLLTLDD
What is the function of this protein?
Seems to be important for efficient replication in vivo.
What are the official names of this protein?
Glyco-Gag protein, Gross cell surface antigen, glycosylated Pr80 gag, gPr80 Gag, gag-gPr80.
What are the subcellular locations of this protein?
[Nextended-MA-p12]: Host cell membrane; Single-pass type II membrane protein. SUBCELLULAR LOCATION: [CA-NC]: Secreted.
Protein: FOGC_ASPRC
Sequence: MAEQTETSTAGYNYVSYGTEQHPIAGLSRVVRHITGHDSEGRSVFLSTDIGDHHRTLGEKQAISNIIYSTNQTPVELNGNHDIEFARNTEPGLHVKDGSVARLIDFAPGVESPLHRAVSLDYGVVIEGVFKMVLDSGEERIMRPGDISVQRATAHKWINVTGNGTLPGRMLFVLLDCNDVYVNGKKMEGYLGTLAKDYEGRSS
What is the function of this protein?
Cupin-domain-containing oxidoreductase; part of the gene cluster that mediates the biosynthesis of flavoglaucin and congeners (including aspergin, dihydroauroglaucin and auroglaucin), prenylated salicylaldehyde derivatives carrying a saturated or an unsaturated C-7 side chain (PubMed:32134669).  The PKS fogA releases the carboxylic acid (8E,10E,12E)-3,5,7-trihydroxytetradeca-8,10,12-trienoic acid as its product, as well as derivatives with one and two double bonds (PubMed:32134669).  FogA is indeed able to reduce the initial triketide, thus being at least partially responsible for the differently saturated heptyl side chains of flavoglaucin congeners (PubMed:32134669).  The oxidoreductases fogB, fogC and fogD modify the nascent polyketide in fogA-bound form and, together, fogA, fogB, fogC and fogD are necessary for the formation of the aromatic core and the cyclized PKS products are released as salicyl alcohols (PubMed:32134669).  In particular, fogB is responsible for oxidation of a hydroxyl group or reduction of remaining double bond(s) at the C-7 residue whereas fogD is probably involved in the reductive release of the modified PKS products (PubMed:32134669).  The cytochrome P450 monooxygenase fogE is then responsible for the hydroxylation at C-3 of the benzene ring (PubMed:32134669).  The fogE products are substrates of the prenyltransferase fogH and the prenylated benzyl alcohols are subsequently oxidized by the fogF to produce the final aryl aldehydes flavoglaucin and congeners (PubMed:32134669).  The short-chain dehydrogenase fogG does not seem to be involved in the biosynthesis of the prenylated salicylaldehyde derivatives (PubMed:32134669).
What are the official names of this protein?
Cupin-domain-containing oxidoreductase fogC, Flavoglaucin biosynthesis cluster protein C.
What is the protein family that this protein belongs to?
Belongs to the virC family.
Protein: GATA_ROSS1
Sequence: MTLLHQLTLSDAREALMRGEITSVELTDALLARIAAVEPQVRAFLTIDAEGARAQAQAADARRAAGDTSPLLGIPLGIKDVISTQGVRTTCASKMLENYVPVYDATAVARLKAAGAVLIGKLNCDEFAMGSSTENSAFQQTRNPWNLERVPGGSSGGSAAAVAAGEAPATLGTDTGGSIRQPAALCGITGLKPTYGRVSRYGLVAFASSLDQIGPMARTVRDCAIILRVIAGADPFDATCTDHPVPDYEAALTGDIRGLRIGVPREYFVAGMQPEVESAVRVAIDVLRDQGAEVREISLPHTPYALPVYYLIAPAEASANLARFDGVRYGLRVPGESYFDELERTRGAGFGPEVRRRIMLGTYALSAGYYDAYYKRAQQVRTLIRRDYQQAFEQVDVIAAPTTPTVAFPIGAHSDDPLAMYLEDVCTLPLNLAGLPGLVVPCGFAAGLPIGLQLIGRAFDEETLLRIGDAYQRVTDWHTRMPDLPVE
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: LPXH_ECO57
Sequence: MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRTKVHKPWLQTLFLALPLFVRKRIAVRMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
What is the function of this protein?
Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom.  Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine diphosphatase.
What is the protein family that this protein belongs to?
Belongs to the LpxH family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MIAA_PSEA7
Sequence: MPSLPPAIFLMGPTAAGKTDLAMALADALPCELISVDSALIYRGMDIGTAKPSRELLARYPHRLIDIRDPAESYSAAEFRADALAAMAEATARGRIPLLVGGTMLYYKALLEGLADMPGADPEVRAALEAEARAEGWEALHRQLAEVDPESAARIHPNDPQRLMRALEVYRVGGVSMSELRRRQSAEKADFDASGRNQLPYTVAQLAIAPEQRQVLHARIAQRFRQMLEQGFIAEVEALHARSDLHAGLPSIRAVGYRQVWDYLDGKLSYAEMTERGIIATRQLAKRQFTWLRSWSHLHWMDSLAGDNLPRALKYLKTVSILA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: CSM5_MYCTO
Sequence: MNTYLKPFELTLRCLGPVFIGSGEKRTSKEYHVEGDRVYFPDMELLYADIPAHKRKSFEAFVMNTDGAQATAPLKEWVEPNAVKLDPAKHRGYEVKIGSIEPRRASRGRGGRMTRKKLTLNEIHAFIKDPLGRPYVPGSTVKGMLRSIYLQSLVHKRTAQPVRVPGHQTREHRQYGERFERKELRKSGRPNTRPQDAVNDLFQAIRVTDSPALRTSDLLICQKMDMNVHGKPDGLPLFRECLAPGTSISHRVVVDTSPTARGGWREGERFLETLAETAASVNQARYAEYRAMYPGVNAIVGPIVYLGGGAGYRSKTFVTDQDDMAKVLDAQFGKVVKHVDKTRELRVSPLVLKRTKIDNICYEMGQCELSIRRAE
What is the function of this protein?
This subunit might be involved in maturation of a crRNA intermediate to its mature form.
What are the official names of this protein?
CRISPR system Cms protein Csm5, CRISPR type III A-associated protein Csm5.
What is the protein family that this protein belongs to?
Belongs to the CRISPR-associated Csm5 family.
Protein: CDGI_ECOLI
Sequence: MIQSTRISMGLFFKYFLSLTKIDPGQNYISLPSIKSSTHIALLFMVSMGTQKLKAQSFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNAVIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVIIHKPINGSTLIQTKSNDVSIFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYNADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLASLCCNLLLLTLDEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLTNIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQQSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTISIGTVFSTGDTRNISLVMTEADKALREAKSEGGNKVIIHHI
What is the function of this protein?
Catalyzes the synthesis of cyclic-di-GMP (c-di-GMP) via the condensation of 2 GTP molecules.
What are the official names of this protein?
Probable diguanylate cyclase CdgI, DGC.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CD2_HUMAN
Sequence: MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN
What is the function of this protein?
CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types.  CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
What are the official names of this protein?
T-cell surface antigen CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y3376_MYCTO
Sequence: MSISAVVFDRDGVLTSFDWTRAEEDVRRITGLPLEEIERRWGGWLNGLTIDDAFVETQPISEFLSSLARELELGSKARDELVRLDYMAFAQGYPDARPALEEARRRGLKVGVLTNNSLLVSARSLLQCAALHDLVDVVLSSQMIGAAKPDPRAYQAIAEALGVSTTSCLFFDDIADWVEGARCAGMRAYLVDRSGQTRDGVVRDLSSLGAILDGAGP
What is the function of this protein?
Able to hydrolyze geranyl diphosphate (GPP), farnesyl diphosphate (FPP) and geranylgeranyl diphosphate (GGPP) to respectively yield geraniol, farnesol and geranylgeraniol.
What are the official names of this protein?
Phosphatase MT3486.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: ARGC_BRASO
Sequence: MSIRVGIVGISGFGGGEAMRLIAGHPAFEPVYAAGEGSAGQRLSERFPGVPAKLADLVIEKWDPSRLPQLDVLFASLPTGASRDALARIPREVKIVDIGGDHRYADGWTYGLADVWPEAIAGKTRIANPGCFPAAALTALAPLLADRLIAPENIVIDAKTGISGAGRGGGAGFGYAESNENLIPYGLLKHVHMPEIESTIARISGGSAAGLVFTPHLVPMTRGILATIYARGRATSDQCLDAARSFYAGRAFVRVTDKPPQTKWATGSNLAFVSYAADPDRNLVIALGVVDNLGKGAAGQAVQNANLMCGLPETAGLEGAPVWP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOA1_FRATF
Sequence: MSNNNSKLEFVPNIQLKEDLGAFSYKVQLSPVEKGMAHILGNSIRRVLLSSLSGASIIKVNIANVLHEYSTLEDVKEDVVEIVSNLKKVAIKLDTGIDRLDLELSVNKSGVVSAGDFKTTQGVEIINKDQPIATLTNQRAFSLTATVSVGRNVGILSAIPTELERVGDIAVDADFNPIKRVAFEVFDNGDSETLEVFVKTNGTIEPLAAVTKALEYFCEQISVFVSLRVPSNGKTGDVLIDSNIDPILLKPIDDLELTVRSSNCLRAENIKYLGDLVQYSESQLMKIPNLGKKSLNEIKQILIDNNLSLGVQIDNFRELVEGK
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit alpha 1, RNAP subunit alpha 1, RNA polymerase subunit alpha 1, Transcriptase subunit alpha 1.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase alpha chain family.
Protein: GPPA_ECOUT
Sequence: MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLTVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVAANFFDQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIDQESQWQSYVHWPLEVH
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: KTHY_ALCBS
Sequence: MSGRFITLEGGEGAGKSSNLVWLAEALRAEGKTVMVSREPGGTALAESIREVLLAPSNEVMADDTELLLVFAARAQHLEQKIRPALARGEWVLCDRFLDATWAYQGAGRGLDSAAIAALEALVIRDTRPDMTILFDVPVEVGMARAGKRAALDRIEQEDRAFFDRIRQCYLARAAQEPNRFRTVDASQPLESVQQQLARIVEEMQAWP
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: MGDG3_ARATH
Sequence: MMKVVSPRTRSDSITEKVFRRVYSNFNISTVEDEYIHRQRSSDYEKESRLRKRGLEDKEEVMEMEQMGAERIKTVLILMSDTGGGHRASAEAIRDAFKIEFGDDYRIIIKDVWKEYTGWPLNDMERQYKFMVKHVGLWSVAFHGTSPKWIHKSYLSALAAYYAKEIEAGLMEYKPDIIISVHPLMQHIPLWVMKWQGLHKKVIFVTVITDLNTCHRTWFHHGVSRCYCPSKEVAKRALVDGLDDSQIRVFGLPVRPSFPRTILNKNELRKELEIDLNLPAVLLMGGGEGMGPVQKTALALGDSLYNSKESNPIGQLIVICGRNKVLASTLASHEWKIPVKVRGFETQMEKWMGACDCIITKAGPGTIAEALICGLPIILNDYIPGQEKGNVPYVVDNGAGVFTRSPKETAKIVADWFSNNKEELKKMSENALKLSQPEAVFDIVKDIHHLSQQQQRIPLFNEFSY
What is the function of this protein?
Involved in the synthesis of monogalactosyldiacylglycerol, the major structural component of photosynthetic membranes and in the chloroplast envelope biogenesis.  Can use both prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2-diacylglycerol species, but operates with some preference for the eukaryotic one.  Plays a minor role in galactolipid synthesis in chloroplasts (PubMed:11553816).  Is essential for membrane lipid remodeling in phosphate-starved roots (PubMed:18808455, PubMed:31201686).  Acts as the major factor involved in digalactosyldiacylglycerol (DGDG) biosynthesis in phosphate-starved roots (PubMed:18808455).  Does not seem to be required for plant growth under nutrient-sufficient conditions (PubMed:18808455).  Required for membrane lipid remodeling in plants grown in acidic conditions (PubMed:31201686).
What are the official names of this protein?
Monogalactosyldiacylglycerol synthase 3, chloroplastic, AtMGD3, MGDG synthase type C.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 28 family.
What are the subcellular locations of this protein?
Plastid, chloroplast outer membrane.
Protein: COAD_STAAT
Sequence: MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKEGTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELRLTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.