PharMolix/UniProtQA huggingface dataset:
Protein: FHI2B_MOUSE
Sequence: MLSRLGALLQEAVGAREPSIDLLQAFVEHWKGITHYYIESTDENTPAKKTDIPWRLKQMLDILVYEEKQQASSGEAGPCLEYLLQHKILETLCTLGKAEYPPGMRQQVFQFFSKVLSQVQHPLLHYLSVHRPVQKLLRLGGTVPGSLTEKEEVQFTSVLCSKIQQDPELLAYILEGKKIIGKKKTARESTAPPKDIAGYRDKDCPHSDALNRDPGLDKEHCGVPALSIHLPAETEGPENGPGESNLITSLLGLCKSKKSRLALKAQENILLLVSVASPAAATYLTQSTSCCMAIAEHLCQLYRSMPACLDPADIATLEGISWRLPSAPSDETAFPGKEALAAFLGWFDYCDHLITEAHTVVADALAKAVAEKLFVETLQPQLLHVSEQSILTSTALLTALLRQLRSPALLQEAMTFLLGTDQHPAAIEDSPHTLGTHLIMHCDHLSDEISIATLRLFEELLQKPHEQAIRSLVLQNLEGRLYVARGSPEPESYEDTLDLEEDPYFTDGFLDSGLQPSTKPPPAPATSSDGKTAVTEIVNSFLCLVPEEAKTSAFLEENGYDTYVHDAYGLFQECSSRVAHWGWPLGPAPLDSHEPERPFFEGRFLQVLFDRIARILDQPYSLNLQVTSVLSRLALFPHPHIHEYLLDPYISLAPGCRSLFSVLVRVIGDLMQRIQRVPQFSGKLLLVRKQLMGQVPGEHLDHQTLLQGVVVLEEFCKELAAIAFVKFPPHGPYLNFSPPPEGQV
What is the function of this protein?
Able to activate MAPK/ERK and TGFB signaling pathways (By similarity).  May regulate the activity of genes involved in intestinal barrier function and immunoprotective inflammation (PubMed:31862898).  May play a role in cell proliferation (By similarity).
What are the official names of this protein?
FHF complex subunit HOOK-interacting protein 2B, Retinoic acid-induced protein 16.
What is the protein family that this protein belongs to?
Belongs to the FHIP family.
Protein: ISPG_NOCFA
Sequence: MTSTIGLGMPTAPAAVLAPRRKTRQLMVGSVGVGSDHPVSVQSMTTTKTHDVNATLQQIAQLTASGCDIVRVACPRQEDADALATIAKKSQIPVIADIHFQPRYIFAAIDAGCAAVRVNPGNIKEFDGRVKEVAKAAGAAGIPIRIGVNAGSLDKRMLEKYGKATPEALVESALWEASLFEEHGFGDIKISVKHNDPVIMVEAYRQLAAQCDYPLHLGVTEAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPVEEVKVGTQILQSLNLRPRKLEIVSCPSCGRAQVDVYTLANEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGQVIKTVPEHQIVETLIEEAMRIAEEMGEQAGSGEPVVTVS
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: PRP31_DANRE
Sequence: MSLADELLADLEEAGEEDGLYPGGEEGESDGEPGERQVDGGLEDIPEEMEVDYSSTESVTSIAKLRHSKPFAEIMDKISHYVGNQRKNSEVSGPVEADPEYRLIVAANNLTVEIDNELNIIHKFVRDKYSKRFPELESLVPNALDYIRTVKELGNNLEKCKNNETLQQILTNATIMVVSVTASTTQGTMLGDDELQRLEEACDMALELNQSKHRIYEYVESRMSFIAPNLSIIVGASTAAKIMGVAGGLTNLSKMPACNLMLLGAQRRTLSGFSSTSLLPHTGYIYHCDVVQTLPPDLRRKAARLVSAKCTLASRVDSFHESADGKVGYDLKEEIERKFDKWQEPPPVKQVKPLPAPLDGQRKKRGGRRYRKMKERLGLTEIRKHANRMTFAEIEDDAYQEDLGFSLGQLGKSGSGRVRQAQVNDSTKARISKSLQRTLQKQSMTYGGKSTVRDRSSGTSSSVAFTPLQGLEIVNPQAAEKKVAEANQKYFSNMAEFLKVKREKEDKV
What is the function of this protein?
Involved in pre-mRNA splicing as component of the spliceosome.  Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome.
What are the official names of this protein?
U4/U6 small nuclear ribonucleoprotein Prp31, Pre-mRNA-processing factor 31.
What is the protein family that this protein belongs to?
Belongs to the PRP31 family.
What are the subcellular locations of this protein?
Nucleus. Nucleus speckle. Nucleus, Cajal body. Note=Predominantly found in speckles and in Cajal bodies.
Protein: VP2_ROTWI
Sequence: MAYRKRGVKRENLLQQNERLQEKEIENNTDVTMENKNNNRKQQLSDKVLSQKEEIITDVQDDIKIVDEVKKSSKEESKQLLEILKTKEDHQKEVQYEILQKTIPTFEPKESILKKLEDIRPEQAKKQMKLFRIFEPRQLPIYRANGEKELRNRWYWKLKKDTLPDGDYDVREYFLNLYDQILIEMPDYLLLKDMAVENKNSRDAGKVVDSETASICDAIFQDEETEGVIRRFIADMRQQIQADRNIVNYPSILHPIDHAFNEYFLNHQLVEPLNNEIIFNYIPERIRNDVNYILNMDMNLPSTARYIRPNLLQDRLNLHDNFESLWDTITTSNYILARSVVPDLREKELVSTEAQIQKMSQDLQLEALTIQSETQFLAGINSQAANDCFKTLIAAMLSQRTMSLDFVTTNYMSLISGMWLLTVIPNDMFLRESLVACELAIINTIVYPAFGMQRMHYRNGDPQTPFQIAEQQIQNFQVANWLHFINNNRFRQVVIDGVLNQTLNDNIRNGQVINQLMEALMQLSRQQFPTMPVDYKRSIQRGILLLSNRLGQLVDLTRLLSYNYETLMACITMNMQHVQTLTTEKLQLTSVTSLCMLIGNTTVIPSPQTLFHYYNVNVNFHSNYNERINDAVAIITAANRLNLYQKKMKSIVEDFLKRLQIFDVPRVPDDQMYRLRDRLRLLPVERRRLDIFNLILMNMDQIERASDKIAQGVIIAYRDMQLERDEMYGFVNIARNLDGYQQINLEELMRTGDYGQITNMLLNNQPVALVGALPFVTDSSVISLIAKLDATVFAQIVKLRKVDTLKPILYKINSDSNDFYLVANYDWIPTSTTKVYKQIPQPFDFRASMHMLTSNLTFTVYSDLLSFVSADTVEPINAIAFDNMRIMNEL
What is the function of this protein?
Inner capsid protein that self-assembles to form an icosahedral capsid with a T=2 symmetry, which consists of 120 copies of VP2, with channels at each of its five-fold vertices.  This capsid constitutes the innermost concentric layer of the viral mature particle.  It encapsidates the polymerase VP1, the capping enzyme VP3 and the genomic dsRNA, thereby defining the core.  The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus.  Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels formed by VP2 N-termini.  VP2 is required for the replicase activity of VP1 polymerase.  Probably recruits a copy of a VP1-VP3 complex, potentially along with a segment of plus-strand RNA, as a decamer of VP2 assembles.  May activate the autoinhibited VP1/RNA complex to coordinate packaging and genome replication.
What are the official names of this protein?
Inner capsid protein VP2.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP2 family.
What are the subcellular locations of this protein?
Virion. Note=Inner capsid protein. Also found in spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: FH9_ARATH
Sequence: MQNFWFAIFFFLLTCAPPSPLSYASTVTLSRRLLYDYESPLPLPLSPISPPFFPLESSPPSPPPPLPPTPPTTFAVFPTFPANISALVLPRSSKPHHTSPTLLLPALSAVLVIATVIGLALFLYGRHRGQTRHLKNSHCSSSNTSSYGDEQSHITTNFNMAATTSPSEVFYLNTEESDHIRTGGTFFLKQDSPEIRPLPPLPPRSFHHNNYETEVNEEDEEEEEDVFFSPMASLPGSANSSPSHSCSSSCSGWVSPARSFSITMSPPNPRYSDATNLQSPSPERLRVRKNYNGNGSSSLRMFSFWNQNMGFGFPRISSASTSPDRGFIRTPLSSLYSSVSTSPDGLFRKFLDSSPPIWNDFSRNVKSVLLSHTASSRRDFVINIGESSSQQSKVPALPPPTRPPPLVPPSQPFVVQNDVKKQSFSDQPPKQLHWERLRSSSSKLSKEMVETMFIANSSNPRDLPIQNQVLDPRKAQNIATLLQLLNLSTKDVCQALLDGDCDVLGAELLECLSRLAPSKEEERKLKSFSDGSEIGPAERFLKELLHVPFVFKRVDALLFVANFHSEIKRLRKSFSVVQVACEELRNSRMFSILLEAILKTGNMMSVRTNRCGDADAFKLDTLLKLVDVKGLDGRSSLLHFVVQEMMKSEGSVRALEGIRNLNTELSNVKKSADIEYGVLRSNVSRICQGLKNIEALLLLSEESGSYGDQWLKFKERMTRFLKTAAEEIVKIKIRESSTLSALEEVTEQFHGDASKEGHTMRIFMIVRDFLSVLDQVCKEMGD
What is the function of this protein?
Might be involved in the organization and polarity of the actin cytoskeleton.
What are the official names of this protein?
Formin-like protein 9, AtFH9.
What is the protein family that this protein belongs to?
Belongs to the formin-like family. Class-I subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PDXJ_GEOSL
Sequence: MAKLGVNIDHVATIRQARGGVEPDPVAAAAIAEFAGADGITVHLREDRRHIQDRDLRLLRQTVKTKLNLEMAATDEMVGIALSVKPDMCTLVPERRQELTTEGGLDVRVGMQALADAIGRLQDGGIVVSLFIDPDADQVKASSKVGADYIEIHTGTFAEAREWKKEQAELERIENAIKLGTKLGLGINAGHGLNYTNVRKVAALGGIEEFNIGHSIISRAVFTGLDRAVRDMVDLVKYA
What is the function of this protein?
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
What are the official names of this protein?
Pyridoxine 5'-phosphate synthase, PNP synthase.
What is the protein family that this protein belongs to?
Belongs to the PNP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JIL1_DROME
Sequence: MSRLQKQNYEILSGTSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNSNSETMTNGKKSKLNTEGSGSGSGKTLNYNNNNNNNNSISATNGQYTNSSSKTTSASARDYTYRETISPPTPPSPPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDEPNGIEIDESSSSLSKAKSNNAAAAAAAAAAAAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPSRIRLFRGYTYVAPEHLEQMRRDNHCEIQYFNTGLQNIPCRPDDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKFRPSEVDALISCALDTTNHKNIVSYHGTFREKCETWIVMEYLSGPELTASIRMDEDSCREIFLQLVMAVRHIHSKHFIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILDSEWLQYGSNDPDVDIILPQQMVVDLSEDTMEQPTGGMFDDQQQLEFMHDKSAEDEGITLVSEPMDTTVATHESRRNAAAFSSVVAPTTDDEIVHERFDPAFEVQADFYGFDENAPPLPLPEEYYSELPLPEEDRQYIPPPPALIPVEPETTFRRPRTRQQRRTESQLVQPVSVATYEDSKASLRVLMQQLPPPGDNVVARIPKRTHRVVRTLPPTFGTTKREENFYGFSKTAISWRKTRASWRHFCLLINGVQQVLKVRFKKARRVYCLPHIKEEKLDHAYEKPLTFPRPKAQLKRTKREPKVPRPPTRVQPERARAMRQLYQFQ
What is the function of this protein?
Phosphorylates 'Ser-10' of histone H3.  May regulate gene expression by establishing or maintaining the structure of more open chromatin regions.  Also required for normal polytene chromosome structure, for oogenesis and for viability throughout development.  Regulates the structure of polytene chromosomes in salivary glands.  May phosphorylate 'Ser-1' of histone H2A.
What are the official names of this protein?
Chromosomal serine/threonine-protein kinase JIL-1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Associates with chromosomes throughout the cell cycle. Localizes to interband regions along the polytene chromosomes and is enriched almost two-fold on the male X chromosome compared to the autosome.
Protein: ATPF1_NITWN
Sequence: MLAEPETWVAIAFLLLMGVFAYVGVHRTVLSALDRRSARIKNELDDARRLKDEAAKLLADYKARHASAEREAQDIIASARAEAERIAAEAKAKMEDFVARRTKSAEGKIASAEAQAIADVRAAAADAAVAAASSILSNSVKGQLADELLVQGVSEVRSKLN
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b 1, ATP synthase F(0) sector subunit b 1, ATPase subunit I 1, F-type ATPase subunit b 1, F-ATPase subunit b 1.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: FPG_AZOC5
Sequence: MPELPEVETVRRGLLPVLQGAVIESAEARRPDLRWPLPEGFAERLTGRRVEAVGRRAKYLLADLDGGEVLIVHLGMSGSIRIEGAQVKGRPAGFYHPRGEPGTHDHVVFHLAGGATVTFNDPRRFGAMLLVPYDQLDSHPLLSSLGPEPLGNTFHADYLAQACAGRRTNLKAALLDQKVVAGLGNIYVSEALHRAGLSPRRMASTLASASGAPNVRTERLVTAIRDVLREAIQAGGSSLKDHRQVNGELGYFQHNFKVYDREGEPCPTLRCKGHVQRIVQAGRSTFFCATCQR
What is the function of this protein?
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents.  Acts as DNA glycosylase that recognizes and removes damaged bases.  Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG).  Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.  Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
What are the official names of this protein?
Formamidopyrimidine-DNA glycosylase, Fapy-DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase MutM, AP lyase MutM.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: RS13_YERPG
Sequence: MARIAGINIPDQKHTVIALTAIFGIGKTRSQAICVAAGIAEHVKISELSEEQIEKLRDEVAKYVVEGDLRREVTLSIKRLMDLGTYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: GATB_STRPM
Sequence: MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNANTNVIDWSFPGVLPVMNKGVIDAGIKAALALNMDIHKEMHFDRKNYFYPDNPKAYQISQFDEPIGYNGWIEIKLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMRSPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEQFGTKTELKNLNSFSNVRKGLEFEVERQAKLLRSGGVIRQETRRYDEANKGTILMRVKEGAADYRYFPEPDLPLYEIDDAWIDEMRAQLPQFPAQRRAKYEEELGLSAYDASQLTATKALSDFFETAVSLGGDAKQVSNWLQGEVAQFLNAEGKTIEEIRLTPDNLVEMIAIIADGTISSKMAKKVFVHLAKNGGSARAYVEKAGLVQISDPAVLVPIIHQVFADNEAAVADFKSGKRNADKAFTGFLMKATKGQANPQVAQQLLAQELQKLRD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: RL22_PSE14
Sequence: MEVAAKLSGARISAQKARLVADQIRGKKVGEALNLLAFSSKKAAEILKKVLESAVANAEHNEGADVDDLKVSTVFVNEGRSLKRIMPRAKGRADRIVKRSCHITVKVADK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: GATA_RALPJ
Sequence: MTASTIKALSAQLAAKEVSAEELARHYLSRIEAGAHLNAFTHVDAEATLAQARAADARIAAGNAAPLTGVPIAHKDVFVTRGWRATAGSKMLGNYVSPFDATVVERLGAAGMVTLGKTNMDEFAMGSSNENSAFGAVKNPWNLEHVPGGSSGGSAAAVAADLAPAATGTDTGGSIRQPASFSGITGIKPTYGRVSRYGMIAFASSLDQGGPMARTAEDCALLLSAMAGFDPRDSTSLEPGRGGDVEDFGRLLGQPLQGADAARPLAGLRIGLPKEYFGEGLADDVRTTVRAALAELEKLGATLVDISLPKTELSIPTYYVIAPAEASSNLSRFDGVRYGHRAAEYRDLADMYRKSRAEGFGWEVKRRILVGAYVLSHGYYDAYYLQAQKIRRIIAQDFQNVLAGANRQCDVIMGPVAPTVAWKLGEKTSDPVQMYLADIFTLSTSLAGLPGMSVPAGFGANGLPVGLQIIGNYFEEARMLQIAHAFQQATDWHHRQPAA
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit A, Glu-ADT subunit A.
What is the protein family that this protein belongs to?
Belongs to the amidase family. GatA subfamily.
Protein: NUOI_BRUMB
Sequence: MASIAQAAKSLLLKEFASAFALSMRQFFAPKATLNYPHEKGPVSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFATETREELYYDKDKLLANGDRWEREIARNIAMDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CLPX_BACVZ
Sequence: MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGSDNKAADLEKEELLSKVLPEDLLRFGLIPEFIGRLPVIASLEQLDETALVEILTKPKNALVKQYKKMLELDDVELEFEDEALSEIAKKAIERKTGARGLRSIIEGIMLDVMFDLPSRDDIEKCVITGATVADGEAPRLVLKDGTVVGQDKTSA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: CLPS_VIBCH
Sequence: MSKNFEWISPDFDLLEKEKTAVKPPSMYHVVLNNDDYTPMDFVIEILERFFSMDIERATQVMLKVHYEGKAICGTFTAEVAETKVAQVTMYSRENEHPLLCTMEQA
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: EX7S_STRP3
Sequence: MSKTKTFEENLQDLETIVNKLENGDVPLEEAISEFQKGMLLSKELQKTLQAAEKTLVKVMQADGTEVDMDD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS19_BORAP
Sequence: MARSIKKGPFIEKSLYQKVLSSFGSEKRVVIKTYSRSSTIIPEMVSLTISVYNGKTFIPIYITEDLVGHKLGEFSPTRIFRGHAKSDKKGRK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: FRDA_SHEON
Sequence: MFTRKIQKTALAMLISGAMAGTAYAAPEVLADFHGEMGGCDSCHVSDKGGVTNDNLTHENGQCVSCHGDLKELAAAAPKDKVSPHKSHLIGEIACTSCHKGHEKSVAYCDACHSFGFDMPFGGKWERKFVPVDADKAAQDKAIAAGVKETTDVVIIGSGGAGLAAAVSARDAGAKVILLEKEPIPGGNTKLAAGGMNAAETKPQAKLGIEDKKQIMIDDTMKGGRNINDPELVKVLANNSSDSIDWLTSMGADMTDVGRMGGASVNRSHRPTGGAGVGAHVAQVLWDNAVKRGTDIRLNSRVVRILEDASGKVTGVLVKGEYTGYYVIKADAVVIAAGGFAKNNERVSKYDPKLKGFKATNHPGATGDGLDVALQAGAATRDLEYIQAHPTYSPAGGVMITEAVRGNGAIVVNREGNRFMNEITTRDKASAAILQQKGESAYLVFDDSIRKSLKAIEGYVHLNIVKEGKTIEELAKQIDVPAAELAKTVTAYNGFVKSGKDAQFERPDLPRELVVAPFYALEIAPAVHHTMGGLVIDTKAEVKSEKTGKPITGLYAAGEVTGGVHGANRLGGNAISDIVTYGRIAGASAAKFAKDN
What is the function of this protein?
Catalyzes fumarate reduction using artificial electron donors such as methyl viologen.  The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO).  This enzyme is essentially unidirectional (By similarity).
What are the official names of this protein?
Fumarate reductase flavoprotein subunit, Flavocytochrome c, FL cyt.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: DYR_NEIGO
Sequence: MLKITIIAACAENLCIGAGNAMPWHIPEDFAFFKVYTLGKPVIMGRKTWESLPVKPLPGRRNIVISRQADYCAAGAETVASLEVALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPEIDRTHWREAERTERRVSSKGVAYTFVHYLGK
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).
What are the official names of this protein?
Dihydrofolate reductase.
What is the protein family that this protein belongs to?
Belongs to the dihydrofolate reductase family.
Protein: RSGA_CLONN
Sequence: MEGIILKGIGGFYYVKTEERVYECKARGKFRNKKLTPMVGDRVIITPNDNNYGAIEEICTRDNYLIRPQVANISQAFIVFALKNPDVNLDLLNKFLIQCELKNIKSIVCFNKIDLYGDYENHEAVKMVSDAGYDYIFLKAKEETNLDELKSKLKGNINVFCGPSGVGKSTILNKLVGKEVMETGIISERLKRGKHTTRHSELVEVNNGFVVDTPGFSTLDLKFDSKEELKDYFREFYEYKDQCKFNGCLHHKEPKCGVKDAVNNEEINKDRYEFYVKTLEEIIQGGRNKW
What is the function of this protein?
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit.  Helps release RbfA from mature subunits.  May play a role in the assembly of ribosomal proteins into the subunit.  Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.
What are the official names of this protein?
Small ribosomal subunit biogenesis GTPase RsgA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MOTI_CAVPO
Sequence: MLSRKAVAALLLVHVTAMLASQTEGFVPIFTYSELRRTQEREQNKRLRKSLRVQQRSKAAGRLEPQEVMEEEENGVIKLTAPVEIGVGLSSRQLEKHRAVLEALLSEALPPPSLVFGGQRPVTAAWE
What is the function of this protein?
Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
What are the official names of this protein?
Promotilin.
What is the protein family that this protein belongs to?
Belongs to the motilin family.
What are the subcellular locations of this protein?
Secreted.
Protein: TOM34_MOUSE
Sequence: MAPKVSDSVEQLRAAGNQNFRNGQYGEASALYERALRLLQARGSADPEEESVLYSNRAACYLKDGNCTDCIKDCTSALALVPFSIKPLLRRASAYEALEKYALAYVDYKTVLQIDNSVASALEGINRITRALMDSLGPEWRLKLPPIPVVPVSAQKRWNSLPSDNHKETAKTKSKEATATKSRVPSAGDVERAKALKEEGNDLVKKGNHKKAIEKYSESLLCSSLESATYSNRALCHLVLKQYKEAVKDCTEALKLDGKNVKAFYRRAQAYKALKDYKSSLSDISSLLQIEPRNGPAQKLRQEVNQNMN
What is the function of this protein?
Plays a role in the import of cytosolically synthesized preproteins into mitochondria.  Binds the mature portion of precursor proteins.  Interacts with cellular components, and possesses weak ATPase activity.  May be a chaperone-like protein that helps to keep newly synthesized precursors in an unfolded import compatible state (By similarity).
What are the official names of this protein?
Mitochondrial import receptor subunit TOM34, Translocase of outer membrane 34 kDa subunit.
What is the protein family that this protein belongs to?
Belongs to the Tom34 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: PORED_MESAU
Sequence: MASWVGTELSALNPLRTLWLALAAAFLLALLLQLAPAGLLPNCALFQDLIRYGKTKLSGPRRPAVCRAFDVPKRYFSHFYVVSVLWNGFLLWFLSRSLFLGAPFPNWLRALLRTLGSTQFRALEMESKASQMLVGELALSAFLVLVFLWVHSVRRLFECFYISVFSNAVMHVVQYCFGLVYYVLVGLTVLSQVPMDDKNVYMLGKNLLLPARWFHVLGMMMFLWSSAHQYECHVILSNLRRNKKGAIVHCQHRIPFGDWFEYVSSANYLAELMIYISMAVTFGFHNFTWWLVVAYVFFCQALSAFFNHKFYKSTFVSYPKHRKAFLPFLF
What is the function of this protein?
Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol.  Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation.  Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.  Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
What are the official names of this protein?
Polyprenol reductase, 3-oxo-5-alpha-steroid 4-dehydrogenase 3, Steroid 5-alpha-reductase 3, S5AR 3, SR type 3.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.