PharMolix/UniProtQA huggingface dataset:
Protein: ADEC_DESHY
Sequence: MNDKDLKKLTAKSLGREKAELVLKNAQVINVFSEEILVRDVAVGDGMIVGVGQYQGREEVDLSGKYLCPGFIDAHLHLESTLVAPPELIHSALQWGTTTFIIDPHEVVNVAGEEGLDYMLEQTEGLAANVFVMLPSCVPAVPFEENGGVFTAEKMEPYLANPRVLGLGEVMDYVSVIGAEEEMVKKLRLFRERIKDGHAPYLQDKQLAAYALAGIKTDHECIDYAYALEEIRNGMQVLIREGSGARNLAAIVRGIRENNLDTGNFSFCTDDKHINDIQREGHISYNIKKSIALGLPPLKAIKMATLNTARCYNLTELGAVAPGYQADFVILDSLEEVAVHAVYHKGKKVEREKKIDIKPCSEQLRRTVHLPALSAEDLKLAVPDSPSSLIQMSEGQITTKHVRDVLPARDGCFVPNAQYNKVVVVERHKGTGHFAVAPVLGFNLGQGAIATSVSHDSHNVVAIGDNDESILLALQELQRVQGGYTMIREQRVLATLPLPIMGLISDAGHQAVESMLNTMVGYAHEMGVPASIHPFIALSFIALPVIPEIRITTRGLYDAVEQKFIRYIP
What are the official names of this protein?
Adenine deaminase, Adenase, Adenine aminase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
Protein: AROC_SYNC1
Sequence: MNRLRYLTAGESHGPSLTAIIEGMPANLELNEGDINRDLARRQLGYGRGGRMLIEKDKVNFTSGVRWGKTLGSPITLSIQNRDWENWGKKMSPVAEDFVEGMAITHPRPGHADLTGVIKYRQDDARNILERSSARETAARVAVGALCKKFLADLGMSVLGYVSELGGVCADASLEDYHERFALSEESPCRTFDAEAEQRMIKAIDRAKEDGDSLGGVVEVAVLGAPVGLGSYVQWDRRLDGRLAYAMMSIQAFKGVEIGLGFEAGRRPGSQVHDEIFHQGDEFVRKTNRAGGLEGGMTNGAPIIVRGAMKPIPTLYQPLQTVDFRTKDAFAAVVERSDVCAVPAAAVVAEAVVAIEMAQAMLEKFGGDAMEEVKQNLQAYGEYVQRF
What is the function of this protein?
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis.  This reaction introduces a second double bond into the aromatic ring system.
What are the official names of this protein?
Chorismate synthase, CS, 5-enolpyruvylshikimate-3-phosphate phospholyase.
What is the protein family that this protein belongs to?
Belongs to the chorismate synthase family.
Protein: PPAC_STAEQ
Sequence: MTKTFIFGHKNPDTDAISSALIMADFEQQTGNTEAKAYRLGEISAETQFALDHFNVEAPELLNEDLKGQDVILVDHNEFQQSADTISNATIKHVIDHHRISNFETAGPLYYRAEPVGCSATILYKMYKERGFEIKPEIAGLMISAIISDSLLFKSPTCTKEDVDAAQALKDIANVDLEAYGLEMLKAGASTTDKSAETLVNMDAKSFNMGDYVTRIAQVNTVDIDEVLDRKEEFEKVMLEMSANEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFKVQLDDGMAFLSGVVSRKKQVVPQITEVLTQ
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y793_THEVB
Sequence: MASTFSFDIVSDFDWQELVNAVDQTGREIKARYDLKDTQTALELTKEGLTIHTDSEFTLNSVQTILQQKAAKRQLSLKIFDYGPVEAAGGQRVKQLIKLRRGIPSELAKEISKLIRNEFKKVQASIQGDVVRVSAKSKDDLQAVIQRLKTQDYPVPLQFTNYR
What are the official names of this protein?
UPF0234 protein tll0793.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: EFGM_MOUSE
Sequence: MRLLRVAAALGRGPFPRVPAVLGWQGKQADWKTRRWCSSGPVPNEKIRNIGISAHIDSGKTTLTERVLYYTGRIATMHEVKGKDGVGAVMDSMELERQRGITIQSAATYTMWKDININIIDTPGHVDFTIEVERALRVLDGAVLVLCAVGGVQCQTMTVSRQMKRYNVPFLTFINKLDRMGSNPSRALQQMRSKLNHNAAFVQIPIGLEGDFKGIIDLIEERAIYFDGDFGQIVRYDEIPAGLRAAAADHRQELIECVANSDEQLGELFLEEKIPSVSDLKRAIRRATLSRSFTPVFLGSALKNKGVQPLLDAVLEYLPNPSEVQNYAILNQNDSKEKTKILMNPQRDDSHPFVGLAFKLEAGRFGQLTYVRNYQGELKKGSTIYNTRTGKKVRVQRLVRMHADMMEDVEEVYAGDICALFGIDCASGDTFTNKDNSDLSMESIHVPEPVISIAMRPSNKNDLEKFSKGIGRFTREDPTFKVHFDPESKETIVSGMGELHLEIYAQRMEREYGCPCITGKPKVAFRETIVAPVPFDFTHKKQSGGAGQFGKVIGVLEPLPPEDYTKLEFSDETFGSNVPKQFVPAVEKGFLDACEKGPLSGHKLSGLRFVLQDGAHHMVDSNEISFIRAGEGALKQALANGTLCIIEPIMSVEVIAPNEFQGTVFAGINRRHGVITGQDGIEDYFTLYADVPLNNMFGYSTELRSCTEGKGEYTMEYCRYQPCSPSTQEELINKYLEATGQLPVKKGKAKN
What is the function of this protein?
Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.  Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
What are the official names of this protein?
Elongation factor G, mitochondrial, EF-Gmt, Elongation factor G 1, mitochondrial, mEF-G 1, Elongation factor G1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: NQRE_ALIFM
Sequence: MEHYISLLVKSIFIENMALSFFLGMCTFLAVSKKVKTSFGLGVAVVVVLTIAVPVNNLVYTYLLKENALVAGVDLTFLSFITFIGVIAALVQILEMILDRFFPPLYNALGIFLPLITVNCAIFGGVSFMVQRDYNFAESVVYGFGSGIGWMLAIVALAGIREKMKYSDVPPGLRGLGITFITVGLMALGFMSFSGVQL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: CUTI2_FUSVN
Sequence: MKFFALTTLLAATASALPTSHPVQELEARQLGGGTTRNDLTNGNSASCADVIFIYARGSTETGNLGTLGPSIASKLESAFGRDGVWIQGVGGAYRATLGDNSLPRGTSSAAIREMLGLFQQANTKCPDATLIAGGYSQGAALGAASVEDLDSAIRDKIAGTVLFGYTKNLQNHGRIPNFPADRTKVFCNTGDLVCTGSLIIAAPHLTYGPDARGPAPEFLIEKVRAVRGSA
What is the function of this protein?
Catalyzes the hydrolysis of complex carboxylic polyesters found in the cell wall of plants (By similarity).  Degrades cutin, a macromolecule that forms the structure of the plant cuticle (By similarity).  Allows pathogenic fungi to penetrate through the cuticular barrier into the host plant during the initial stage of fungal infection (By similarity).
What are the official names of this protein?
Cutinase 2, Cutin hydrolase 2.
What is the protein family that this protein belongs to?
Belongs to the cutinase family.
What are the subcellular locations of this protein?
Secreted.
Protein: OBG_STRM5
Sequence: MKLVDEAEIEVFAGNGGNGCIGFRREKFIPLGGPDGGDGGAGGSVYIRADENLNTLVDFRHDRIFKAQRGENGMGRQAYGKGGEDLTITVPVGTVIINVATDEIIGDLTQHGDRLLVAQGGRGGLGNMHFKSSTNRSPRQALPGEPGEERTLKLELKLLADVGLLGFPNAGKSTLIRAVSAATPKVADYPFTTLYPNLGVVKVENYRSFVIADIPGLIEGAADGAGLGAQFLRHLQRTRLLLHLVDISPMEGGVEGISPVEQVRAIERELEKHDPELLQKPRWLVLNKADLMFEDEAKAAAEQIVAELGWKEPWFLVSALGREGTFPIMSRIMAFFDRQKEDELEARNAL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FA83E_HUMAN
Sequence: MAASQLAALEGVDSGPRVPGASPGFLYSEGQRLALEALLSKGAEAFQTCVQREELWPFLSADEVQGLAAAAEDWTVAKQEPSGMAEGATTTDVDAGSLSYWPGQSEQPAPVLRLGWPVDSAWKGITRAQLYTQPPGEGQPPLKELVRLEIQAAHKLVAVVMDVFTDPDLLLDLVDAATRRWVPVYLLLDRQQLPAFLELAQQLGVNPWNTENVDVRVVRGCSFQSRWRRQVSGTVREKFVLLDGERVISGSYSFTWSDARLHRGLVTLLTGEIVDAFSLEFRTLYAASCPLPPAPPQKPSVIGGLQRGRSPHRVSRRRSVAPASPPPPDGPLAHRLAACRVSPATPGPALSDILRSVQRARTPSGPPARPSRSMWDLSRLSQLSGSSDGDNELKKSWGSKDTPAKALMRQRGTGGGPWGEVDSRPPWGGALPLPPAHRLRYLSPARRRFGGDATFKLQEPRGVRPSDWAPRAGLGGQP
What is the function of this protein?
May play a role in MAPK signaling.
What are the official names of this protein?
Protein FAM83E.
What is the protein family that this protein belongs to?
Belongs to the FAM83 family.
Protein: CNE1_USTMA
Sequence: IEQFTSDWSERWSTSQASKFQREDDTEAFKYDGVWSVEEPEVFPGLAGDAGLVLKSKAKQHAISHLFDSPIDPKGKPLVVQYEVKLQKGLSCGGAYIKLLSATEAGVTPDEFSDKTPYTIMFGPDKCGQTNKVHFIFRHKNPKTGEFEEKHVKYPAYPKLAKTSTLYTLVVQPDQSFEIFINNESKKKGSLLEDFEPPVNPPTEIDDPEDEKPADWVDQARIFDPKATKPEDWDEDAPLEIPDQDAVKPDGWLEDEPLTIPDPDAQKPEEWDDDEDGEWFAPSIPNPKCEAAAGCGEWVRPVIRNPAYKGKWTAPLIDNPEYKGVWEPRTIANPNYFEDKSPADFNPIGGVGFELWTMDEDILFDNIYIGHDPSQAKAFAAETFDQKIKIEQRQEDKETAAKAAEDGAGFVGQVRSHVNTFIGRARQDPIGAIKEMPQVAGGLGAAFAGLLGLVGLVGGVLGGGSKVKVTTKDGKKVDAPTAAKGKAKEVTEKVKATGVQAKDAVTKRTNAAAAKVDDAANDE
What is the function of this protein?
Endoplasmic reticulum (ER) chaperone that functions to stabilize non-native glycoproteins and retain them in the ER until they are properly folded or targeted for ER associated degradation (ERAD) (Probable).  Is essential for avoiding plant defense responses in cells with defective N-glycoproteins processing (PubMed:24280385).  With co-chaperone DNJ1, coordinately functions during the tunicamycin-induced unfolded protein response (UPR) (PubMed:26487566).  During biotrophic development, the UPR-associated function of DNJ1 appears to be more important than that of CNE1 (PubMed:26487566).
What are the official names of this protein?
Calnexin.
What is the protein family that this protein belongs to?
Belongs to the calreticulin family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: WTF25_SCHPO
Sequence: MKNNYTSLKSPLDEEDELKTDHEIDLEKGPLPEYDSEEEGALPPYSDHALVNNPLNTHRENHSYGTTDNSSPLLIILLISFTSIILFNAPAFCYLKYKDAFFKNYGAAEWTLFGFWCLVCTLALIFLTYFYETWSKACGKGIKHFLKNWRNMIFAFCKSSLFCLVLLKAENKLSSHLGDQRWGWKCSASAFTFMAVSSILIFIAETVEPGSCSTDLVKRTLAFYGYEIRQHVNEDATILLREMNPESEA
What is the function of this protein?
Acts as a suppressor component of the dual wtf meiotic drive system, and can suppress but not confer meiotic drive by compatible poisons (By similarity).  Wtf meiotic drive systems promote unequal transmission of alleles from the parental zygote to progeny spores by encoding a poison and an antidote from the same locus; the poison is trans-acting and forms toxic aggregates in all spores within an ascus, wherease the antidote is spore-specific and targets aggregates for degradation by the vacuole (By similarity).  Meiotic drive by wtf systems therefore lead to poisoning of all progeny that do not inherit the dual poison/antidote allele, or express a compatible antidote (By similarity).
What are the official names of this protein?
Meiotic drive suppressor wtf25.
What is the protein family that this protein belongs to?
Belongs to the WTF family.
What are the subcellular locations of this protein?
Spore membrane; Multi-pass membrane protein. Vacuole membrane; Multi-pass membrane protein.
Protein: ATPD_PSYA2
Sequence: MADLSTLARPYAKAAFDYANENGAVNEWEDFLFVAATVVNDKSFSTWLDNPAVSAEHKSAALVDLYDTQVASANDSAFKQLLDATKGVRPDSNASYPKVSVAFSNFVKQLSEQERLALLPEVYEHYRRHKAVSLKQLDAYVTSAYPLTDDQRDMLQARLAASLNASVVIHESVDASLLAGVTIKVGDKVIDDSMRGKLQQLKTQLTA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: THIG_BART1
Sequence: MLNLYGREFSSRLMLGTAQYPSPAILRDAICKSGTEIITVSLRRESAGGKQGGQFWQFLQELDITILPNTAGCYTVKEAVTTAYLARDLFKTSWIKLEIIGNADTLQPNVFSLIEAAKILNSEGFHIFAYTTDDLIVAEKLLDVGCRVIMPWCAPIGSAKGPHHIDGLRSIRAYLPDVTLIVDAGIGRPSHAAVAMELGYDAVLLNTAVAKAGDPILMAEAFSKAIQAGRMGYKAGILEARNVAVPSTPVIGKAVF
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXPA_SHIF8
Sequence: MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACVREEIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALVLVGLAGSELIRAGKQYGLTTREEVFADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWATVAAQTVCLHGDGEHALAFARRLRATFAKKGIVVAA
What is the function of this protein?
Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
What are the official names of this protein?
5-oxoprolinase subunit A, 5-OPase subunit A, 5-oxoprolinase (ATP-hydrolyzing) subunit A.
What is the protein family that this protein belongs to?
Belongs to the LamB/PxpA family.
Protein: Y2139_SACEN
Sequence: MSEEQTGIEVAVVSGLSGAGRSTAAKCLEDLGWFVVDNLPPELIATMVELGARSSGAITRVAVVMDVRSRAFTEDLGSVIKDLDARGYKPKVLFLEATDEVLIRRFEQVRRGHPLQGEGRLADGIAAERSLLSRLRSEADLVLDTTALSVHQLRAKIEDAFGTEASTRTRVTVLSFGYKYGLPMDADLVMDCRFLPNPFWIPELREFNGLDEEVRNYVLGQEGAEEFLVNYQQLLRLVGAGYHREGKRYLTLALGCTGGKHRSVALVEELARRLADDEGMMVKTVHRDLGRE
What is the function of this protein?
Displays ATPase and GTPase activities.
What are the official names of this protein?
Nucleotide-binding protein SACE_2139.
What is the protein family that this protein belongs to?
Belongs to the RapZ-like family.
Protein: NADK_BIFLS
Sequence: MAKRNAVVVTHTRLRQTGTVVAEAVSQLRVAGFEVTIIDNTEAPDFGVQPPCVSDDTEIVVVLGGDGTILRAAELVHCTQVPILGVNMGHVGFLAEFESFQIDEAIRRVATHDYSIDERMIAHVDVWLPGATKPIEDWALNDITLERADRGKMVELSIRVDDVEMNSFGADGVIVSTPTGSTAYAFSAGGPVMWPNVKALQLIPLAAHALFARPLIIGSGSTFTIDILDDSMSEGWICCDGRRQRALPQGTRVMVRESRDTLRLARLSGMPFTNRLVSKFDLPVVGWREHARNEASSQPLHHGHTFPAAAYAAGVAGDAGVAGTEPDKPGERDGKAGA
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS12_PSE14
Sequence: MATINQLVRQPRKRIVEKSDVPALQNCPQRRGVCTRVYTTTPKKPNSALRKVCRVRLTNGFEVSSYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHTVRGSLDTSGVKGRNQGRSKYGTKKPK
What is the function of this protein?
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone.  Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together.  The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S12.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS12 family.
Protein: LONP2_ASHGO
Sequence: MGLFGKDRGERIAEFPCYLLETGTHLVPLPGILYNLVIERTYGERILGQFRGIGEAVDGALTGAGEAAEVPGRVAEVMKAFQERYDSGDKTQAVYICLVTEAAAGRHIGCIARLTGARAEGGELSVLLRGLVRAVVGQPVPSRRNEMWNGSVTVLDDAQRVATWGARQLDFARQGVFGAFEELDAGIGTFTARFKSSQKRGADGAAHLLTLSPLANTLFFHFSRSSFERSWKILRTMMHGFRDAKKDIRTAMDMLSVADLTVGLLPTTTAQRLEFLQAEDPAARIKTFVRHMQQLLEVFGSLYRATEYVHDRFETHGPIAKSQLIANQLRSLRFYIDDIKRNKPESGPGGRSRRLLPRPASGNSAAAGEEDDSEDSELVAIKRYVDEIEVKGVHADGVKMLKKDYRSLSKMHVQSTEYQMLRNYFDFIMGIPFGIYVSTPEIDLVASSRKLDNDHYGLVQVKKRLLEYLCVLKLSANSPGVTADAGAIEDGSATKRAVVYENKAQEQRKTKVPFLLLVGPPGVGKTSVAKSVADVLGRRFQRISLGGIHNEAEIRGHRRTYVGAMAGMIVNALCKAGCMNPLILLDEIDKVLSVPAGAGASRLNGDPGAALLEVLDPEQNHTFTDHYVGFPVDLSQVLFFCTANDLSGMSEPLVDRMEVIHIEGYTYEEKIAIGRHFLLPKQIRLNSFDMTGINLSLTDDAWRTVVVDYTREAGVRNLDRQLGAIVRGKIVEYVENNMSGSGDDVVTQKNLPKFLGLPPHSLREEVTQTTSFAEKYGVVHGLSYNSDGTGGVLVFEVIRSGDSRDKRLTVQTTGNLGTVLSESVSIATSLVKSLLARHVVHSSADDTSVAEFFRSECHLHVPFGAVPKDGPSAGAAISLALLSLALKRPVDPALCVTGEITLRGKILPVGGVKEKLLAAQLQGMGLALVPRGNRNDLVELAEDNAETQQRLLADPALPELATLQHKLGMAVHYCSDFRDLVLHAWPTADNLWHACEDSSVRPQL
What is the function of this protein?
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix.  Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
What are the official names of this protein?
Lon protease homolog 2, peroxisomal.
What is the protein family that this protein belongs to?
Belongs to the peptidase S16 family.
What are the subcellular locations of this protein?
Peroxisome matrix.
Protein: SYL2_METS5
Sequence: MITIPSHEFTDLLNEISKKWQEEWSKNRIFEADPKDQKKFFTTVAFPYPNSPFHLGHGRTYVTGDVYARFMRMKGYNVLFPMGFHFTGTPIITMADDVAKGDKDLLDIFQNIYEIPADVIPKLSDPLFMANYFKEDIKAAMREIGLSIDWRREFTTIDPQFSAFIVWQFSKLQKKGYVVKDTHPVGWCPVHNLPVGMHDTKGDMEPEIGEYVVIFFESKMGALAAATLRPETIFGAVAVWVNPKATYTVAEIWGKKVIVSEKAAEKLKFQTDVKVLEKVSGSDLLKIVAINPITGKEIPILPADFVDPTTATGVVMSVPAHAPFDYFYLKKAKVGIEPIPVVAVEGQGDAPAKDLVESSHPKNDADLKKLTEQLYRLEFNKGLMRSDILRLVKDELRAELSVVAGKQVPEARKMVTDILIQRKAGTKMLEIMNKPVYCRCGNEVVVKILQDQWFLDYGNPEWKAKAKKLLDSMRVIPEETRKDFEYALDWLQKRACARTRGLGTPLPWDKKWIIESLSDSTIYMAYYTLSHKIKEFGLHPSQLTEETWDYIMLGEGDVKAISERNKIGVDALQELRRHFTYWYPLDLRHSGPDLIPNHLSFFIFNHAGIFPENLWPRGVAVNGFILYEGKKMSKSLRNIVPLRKAIRTYGADVIRIALSSLVDMSSDANFTEAGARAIADNLKRFYELMQMQDGSTIDGTPEKWLRSKLHRLVRDVTPLMESMRFREVINELLFNLSSYINEYLEMVRSESREYNRDVIREVVETWTKLMAPFAPHLTEEMWHQLGHNTFLSLESWPTPDNSKINDQIELEHEYHKLLIEDIRAILNVYKGKPSSVLLYVHDGSLNQVVKSALDVLNSGGTMKDFMQKNTPKSKEEARVLQRIMQYVTEMPETVKKLIYSNVNEMEVTRKGVPLLRYKLNLEIEVLAYTQEVKQKLNKDALPYRPAILVK
What are the official names of this protein?
Leucine--tRNA ligase 2, Leucyl-tRNA synthetase 2, LeuRS 2.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COMA_CONMR
Sequence: MMSKLGVLLCIFLVLFPMATLQLDGDQTADRHADQRGQDLTEQQRNSKRVLKKRDWEYHAHPKPNSFWTLV
What is the function of this protein?
May act as a neurotoxin.
What are the official names of this protein?
Conomarphin-Mr3, Conomarphin, Marmophine, Mr-1.
What is the protein family that this protein belongs to?
Belongs to the conotoxin M superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ZCHC9_MOUSE
Sequence: MTRWARVTTSNSKRPLSATSWEDMKKGSVERADQSLPNRKQCQSSRLPLRNDSPQAKRKKNKKKKEYLNEDVNGFMEYLKQNSQVLHNGQLIAADSQEVREEIAVALKKDSRREGRRLKRQAAKKNAMVCFHCRQPGHGIADCPAVLESQDMGTGICYRCGSTEHEMSKCRANVDPALGEFPFAKCFVCGEMGHLSRSCPDNTKGVYADGGSCKLCGSVEHFKKDCRENQNSDRIITVGRWAKGMSADYEDVLDVPKLQKPKTKVPKVVNF
What is the function of this protein?
May down-regulate transcription mediated by NF-kappa-B and the serum response element.
What are the official names of this protein?
Zinc finger CCHC domain-containing protein 9.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Note=Expressed throughout the nucleus and concentrated mainly in the nucleolus.
Protein: NRDR_AZOVD
Sequence: MHCPFCSAHDTKVIDSRLVAEGDQVRRRRECQACGERFTTFETAELVMPRVIKQDGSRQPFDEDKLRAGMQRALEKRPVSVERLEAAIGRIKHELRATGEREVKSRVLGELVMAELRKLDEVAYIRFASVYRRFQDLNEFREEIERLSREPSKP
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: VA5_VESMC
Sequence: NNYCKIKCLKGGVHTACKYGSLKPNCGNKKVVSYGLTKQEKQDILKEHNDFRQKIARGLETRGNPGPQPPAKNMKNLVWSDELAYIAQVWANQCQYGHDTCRDVAKYQVGQNVALTGSTAAVYNDPVKLVKMWEDEVKDYNPKKKFSENNFLKIGHYTQMVWANTKEVGCGSIKYIQENWHKHYLVCNYGPSGNFQNEELYQTK
What are the official names of this protein?
Venom allergen 5, Allergen Ves m V, Antigen 5, Ag5, Cysteine-rich venom protein, CRVP.
What is the protein family that this protein belongs to?
Belongs to the CRISP family. Venom allergen 5-like subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: EFP_AQUAE
Sequence: MATEIDINRIQKDIFIEHKGEPYRVLDYEHVKPGKGQAFVRVKAKNMLTGNVTELTFKASDRIPLADFEQVYATYSYNDGENYYFMNTQTYDMIAVPKEKIEEEAKFLKEGMEVIVFLYKGQPIGIELPKHVELQVVETEPAFKGDTQAGGTKPAKLETGAVIQVPFFVKEGDIVKVDTRTGSYVERVKEAK
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity).
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PUR8_HUMAN
Sequence: MAAGGDHGSPDSYRSPLASRYASPEMCFVFSDRYKFRTWRQLWLWLAEAEQTLGLPITDEQIQEMKSNLENIDFKMAAEEEKRLRHDVMAHVHTFGHCCPKAAGIIHLGATSCYVGDNTDLIILRNALDLLLPKLARVISRLADFAKERASLPTLGFTHFQPAQLTTVGKRCCLWIQDLCMDLQNLKRVRDDLRFRGVKGTTGTQASFLQLFEGDDHKVEQLDKMVTEKAGFKRAFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPYKRNPMRSERCCSLARHLMTLVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTILNTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKAGGSRQDCHEKIRVLSQQAASVVKQEGGDNDLIERIQVDAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVYPLLKPYESVMKVKAELCL
What is the function of this protein?
Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
What are the official names of this protein?
Adenylosuccinate lyase, ADSL, ASL, Adenylosuccinase, ASase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
Protein: RL20_SINFN
Sequence: MARVKRGVTAHAKHKKTLKAAKGFYGRRKNTIRAAKAAVDRSKQYAYRDRKVNKRNFRALWIQRINAAVREFGLTYGRFIDGLNKAGIEVDRKVLSDMAIHEPAAFGALVEASKKALAYLKEAGTANEFESAVR
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: VPS27_ASPFU
Sequence: MAGWFSSTSPLDEQVERATSSSLEDMALNLEISDLIRSKSVQPKEAMRSLKRRLENRNPNVQIATLKLTDTCVKNGGSHFLAEIASREFMDNLVSLLTTEGAPLNTDVKEKMLELIQDWAMAAQGRMDLNYLGETYRKLQNEGFRFPPKNEISGSMLESSAPPEWIDSDVCMRCRTPFSFMNRKHHCRNCGNVFDAQCSSKTLPLPHLGILQPVRVDDGCYVKLTSKSSLPSNLSDRSAFKNHSITKANAMEPRGARAEGGFDDDLRRALQLSLEEAQSKGSSGYVPSTRINDEPAKTTTQTNHEEEEDADLKAAIEASLRDMEEHKKKHAAALKSNAAATDSSTRDSAAATPLPKNPYELSPVEVENIHLFAALVDRLQHQPPGTILREPQIQELYESIGALRPKLARSYGETMSKHDTLLDLHAKLSTVVRYYDRMLEERLSSAYSQHSLGYATAPGGSPYPNIYPTMPSHIPEGKTGAENFYYGNPVADRAPPVGNTYGYPHSSRDIREPTAAPSGPISSGVYNQPGQAVPQNPPWNGNAPSVASPQPSAPSTPFPNNSSGYPGPSASTQYYASAPHPEQDSNAYSGPRPGETDVSHQSSPNMRRDSYYQSAGAPVTARASAPEQSPPTDQGQSPAYMQYGDSHSAQSTGQPTHQHQPTAPPPQSYYFQHQPPQSAPLPTHSQTPGAPYGTYPGGDVSPIGAPAPAVHYQPAAQTKPAVEESLIEL
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 27.
What is the protein family that this protein belongs to?
Belongs to the VPS27 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.