PharMolix/UniProtQA huggingface dataset:
Protein: RPOB_VIBPA
Sequence: MVYSYTEKKRIRKDFGTRPQVLDIPYLLSIQLDSFDKFIEQDPEGQYGLEAAFRSVFPIQSYNGNSELQYVSYRLGEPVFDVKECQIRGVTYSKPLRVKLRLVIFDKDAPAGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARVIPYRGSWLDFEFDPKDNLYVRIDRRRKLPASIILRALGKSTEEILDIFFEKVNFEVKDQTLLMELVPDRLRGETASFDIESNGKVYVEQGRRVTARHIRQLEKDGVDHIEVPVEYIVGKVASKDYINEATGEIIVNANQEISLEALANLSQAGHKALEVLFTNDLDHGPFMSETLRIDSTVDRISALVEIYRMMRPGEPPTKEAAEALFESLFFSEERYDLSTVGRMKFNSSIGREDAQEQGTLDETDIIEVMKKLIAIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDAVMPQDLINAKPISAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHVTHYGRLCPIETPEGPNIGLINSLSAFARCNEYGFLETPYRRVVDGVVTDEVDYLSAIEEGQFVIAQANAKLNEDGTFADELITARQKGESGLHPREHAQYMDVATNQVVSIAASLIPFLEHDDANRALMGANMQRQAVPTLKADKPLVGTGIERNVAVDSGVTAVAKRGGVIQSVDASRIVVKVNEEELVPGEAGIDIYNLTKYTRSNQNTCINQRPCVMPGEPVARGDVLADGPSTDLGELALGQNMRIAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELTCVARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPNSVSGTIIDVQVFTRDGVEKDKRALEIEQMQLKEAKKDLTEEFQILEGGLLNRVKAVLIEGGYSEAKLDATDRKKWLELTLEDDALQTQLEQLAEQWDELKADFDKKFETKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPVEDMPYDEKGQPVDIVLNPLGVPSRMNIGQILEVHLGLAAKGIGDKINQMVKEQQELAKFREFLQKVYDLGDTRQKVDIASLSDDEVRTLIKNLRGGLPIATPVFDGAPEASIKALLELADLPTSGQLTLFDGRTGDAFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHSMEPGMPESFNVLLKEIRSLGINIELEDEE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: RL6_STRPF
Sequence: MSRIGNKVITMPAGVELTNNNNVITVKGPKGELTREFNKNIEIKVEGTEITVVRPNDSKEMKTIHGTTRANLNNMVVGVSEGFKKDLEMKGVGYRAQLQGTKLVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGKGIRYVGEYVRLKEGKTGK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: MED10_KLULA
Sequence: MVEQNLEKLQTDLVETEQRLAAIIDSFIELGVYVYDFPGTEDSMQGMVTNMQRNVDRMKQLNQQANDPESQLQNFLVPLDVLQYIEDGRNPDVYTREFVEAIRRSNQYQRAKIHGLNKLRDSLAEKIIDELPELQPHVESIIARTSPQRTDPISPSIVDKP
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 10, Mediator complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y088_MYCPN
Sequence: MHWIFKKEPNISVQQNPTKENVSDVSMIEINNLTALERDEKVETEDINTNVIANTYTVQANVPTAFQTSETNSNTVTNVPKSPELISIQRLERLKNRYTFL
What are the official names of this protein?
Uncharacterized protein MPN_088.
Protein: RL10_BURMA
Sequence: MPLNREDKQAVVAEVAAQVAKAQTVVLAEYRGIAVGDLTTLRAKAREQKVYLRVLKNTLARRAVEGTPFAPLAEQMTGPLIYGISEDAIAAAKVVHDFSKSNDKLVIKAGSYDGKVMDKAGVQALASIPSREELLSKLLFVMQAPVSGFARALAALAEKKQAEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: AXEP_FLAJ1
Sequence: MKLILREYNLKLKHTFTISRESIDFQPSLIVELQSEGFSGFGEATSNPYYNITVPMMMQDLEKIRSIIEDTENETPDVFWAKIHPYLKNDMFALCALDLAYNDLYARKKGKKLYELWNYTTERNPMTDYTIGIASIDKMVSKMQELPWPIYKIKLGTKEDIEIVKELRKHTNAVFRIDANCGWGVEETINNSVELKKLGVEFLEQPMKADNWEGHKEVFKHSVLPVIADESCIIEEDVAKCFNHFHGVNVKLVKCGGLTPGKRMIEEAKKLGLRTMVGCMTESTVGISAIAHLLPQLDYVDMDGALLLAEDIATGVTIKDGVVSYSNLNGTGVTLL
What is the function of this protein?
Catalyzes the epimerization of D-Ala-D-Ala to D-Ala-L-Ala.  Has broad substrate specificity and catalyzes the epimerization of a variety of dipeptides containing an N-terminal Ala followed by Ser, Thr, Val, Met, His, Phe or Trp (in vitro).
What are the official names of this protein?
L-Ala-D/L-amino acid epimerase, L-Ala-L-Xxx epimerase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family.
Protein: RS2_SHESA
Sequence: MTTVSMRDMLQAGVHFGHQTRYWNPKMKPFIFGARNGVHIINLEHTVPMFNEALAFISNVASKKGKVLFVGTKRAAGEAIKEAAISCDQYYVDHRWLGGMLTNWKTVRQSIKRLKELESQSVDGTFDKLTKKEALMRTRELEKLEKSLGGIKNMGGLPDVLFVIGADHEHIAIKEANNLGIPVVAVVDTNSAPDGVNYIVPGNDDAMRAIRLYTTSVAAAANAGRGQDLAVQAEQDGFVEAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: DHPON_PAENI
Sequence: MTVTSQVKPEDEMLNWGRLILDGVSYSDMVGARDRPKEITWFDYWMSLANEYEQEAERKVALGHDLSAGELLMSAALCAQYAQFLWFDERRQKGQARKVELYQKAAPLLSPPAERHELVVDGIPMPVYVRIPEGPGPHPAVIMLGGLESTKEESFQMENLVLDRGMATATFDGPGQGEMFEYKRIAGDYEKYTSAVVDLLTKLEAIRNDAIGVLGRSLGGNYALKSAACEPRLAACISWGGFSDLDYWDLETPLTKESWKYVSKVDTLEEARLHVHAALETRDVLSQIACPTYILHGVHDEVPLSFVDTVLELVPAEHLNLVVEKDGDHCCHNLGIRPRLEMADWLYDVLVAGKKVAPTMKGWPLNG
What is the function of this protein?
L-nicotine is used as a growth substrate.  Plays a role in nicotine catabolism by cleaving a C-C bond in 2,6-dihydroxypseudooxynicotine.
What are the official names of this protein?
2,6-dihydropseudooxynicotine hydrolase.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily.
Protein: RL3_FRATF
Sequence: MSLGLVGRKCGMTRIFTEDGVSIPVTVVQVEPNKVTQVKTVEKDGYNAIQVTTGFKKRSNVNKPMAGHYAKASVEPGRGLWEFTVDAAAEYQVGSSFDATMFEAGQKVDVRGVSKGKGFQGGVKRHNFATQDATHGNSLSHRVHGSTGQNQTPGRVFKNKKMAGHLGNENVTIQSLEVVRVDAENGLLLLKGGIPGSVGGDIIVTPAVKS
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: HNF6_MOUSE
Sequence: MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVGHRGSHLPPAHPRSMGMASLLDGGSGGSDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSGSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSLDKWQDEGGSNSGSSSSSSSTCTKA
What is the function of this protein?
Transcriptional activator.  Binds the consensus sequence 5'-DHWATTGAYTWWD-3' on a variety of gene promoters such as those of HNF3B and TTR.  Important for liver genes transcription.  Stimulates the expression of Onecut3 in the developing endoderm.
What are the official names of this protein?
Hepatocyte nuclear factor 6, HNF-6, One cut domain family member 1, One cut homeobox 1.
What is the protein family that this protein belongs to?
Belongs to the CUT homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATPG_GEOUR
Sequence: MASLKSIKKRIVSVKNTRQITKAMKMVSAAKLRRAQENVVAARPYAKKLGEVLERLSKSQDVDGSPLMEKRQGGKALLIIVSSDRGLCGGFNANICKAAERFAKERGSEFTELSMMTIGRKGYEFLKNRHKIYKNYANIFGTLNYQTAALIARELIDGYLAEEYDEVYLLFNAFKSVMTQDITLEQLLPVTPEVAAEEEYAPEYIYEPSKAALLDELLPKHIEVQMFKAMLESVASEHGARMTAMDSASKNASEMIGKLTLQYNRARQAAITTELMEIISGSESIKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PVK1_BLADU
Sequence: GSSGLIPFGRT
What is the function of this protein?
Mediates visceral muscle contractile activity (myotropic activity).
What are the official names of this protein?
Periviscerokinin-1, BlaDu-PVK-1, PVK-1.
What is the protein family that this protein belongs to?
Belongs to the periviscerokinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: YIDC_CHLL2
Sequence: MDRNSVTGLALIALIMIVWLQFMSPDKKSVQPDNRPKAQTTATVSQEKTEAPAALRSDTFGVFAEASTGAEELVTVDNELFTMTLSSKGATIKSVVLKNHLDGQLKPFDLVSSHDKGALSLLFLNVEGKKIDTRELYFRLVSQEKKQTLSGKKIAVVRYRLDINPQQAIDIVYRFSGNSYKVDYDVKLTGFDNALAGNEYQLQWDGGLAYSEKNREDESHNALAGAFLGGSLVKIDASKENQTYREEQSGEAGWVAVRNKYFVAALIPGSKTEGIYLEGKKGSGHFEEYLASLKMSVPSTEKVASNHFSLYIGPLDYNTVKTLDANLEKIMDFGWDWLTRPFAEYVILPVFTWMNGFISNYGLIIIIFALLIKLVTYPLSMASTKSMKKMAALQPMLKELQEKYKDNPAKLQSELGRIYKEAGVNPLGGCLPVVLQMPLLFAMFYVFRSSIQLRHHGFLWAKDLSVPDSILDFGFSIPVYGDHIAVFPILMGVTVFIQQKITPTTQSNDQMKMMLYIFPVTMLLFFNNLPAGLGLYYLMFNVFSVAQQFYINSTTSTDDVPKAALEAASAAVASKKKKGSSKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.  Aids folding of multispanning membrane proteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: Y306_CHLMU
Sequence: MYPVEYPPPLYSSCKHILSLTAKQLKTKAFVVFSASLSLIIGLITGCCLLFASPPAFITSGICLALLVSVISFFGCRKLIPYGIQRLISYTKSLPALSDSLIDFLKTESTSISSLLPDPKLKNCFKGTSSEYKKFFFDHPETLLSSAFMDWTPQIGPSAPQQTKTIVLSHYCLPFSLTLSTLDFETLHTYIVKSNKLRCHVGYAHQLPPANPVIRQARQGVLQQLYNTGTETFFIPIQESALLQQEELFKTLFRHYVQIIERNLSSRVLLLEPLKTPVHTHKARTLESLALFCALEYLCYTTLGDWGTKELDPTPPLDYKDFFTILIKKQCPASNMRISSPARPMNATKLTTIVLSGLEEEDKLGLLGQMQPFLFTAEIAHPQRFEATLIQNVLDDIA
What are the official names of this protein?
Uncharacterized protein TC_0306.
What is the protein family that this protein belongs to?
Belongs to the chlamydial CPn_0129/CT_036/TC_0306 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y6928_PSEAB
Sequence: MRIWIDADACPKAAKELVCKFALKRKLEVWMVAGQPQVKPPFACVRLVVVESGMDAADDYLVEQAEPGDLAICSDVPLADRLIKKQVAALDPRGREFDARNMGDKLAMRNLMADLRDQGQMGGGQAPYAERDRQAFANALDRLLTRLQREADLRASQPHR
What are the official names of this protein?
UPF0178 protein PA14_69280.
What is the protein family that this protein belongs to?
Belongs to the UPF0178 family.
Protein: PSB1_KORCO
Sequence: MLMKGTTTVGVKFKNGVIVASDKRATSGTFVASKSAVKTLKITDYAVATISGLVADGQYLVNNVRTIADLYSLDTERPLSVRGIARILAFLLRRYRPYFLLAQLIVGGVDREGAHLFNVDPFGTLTEEDYLATGSGSPVAISVIESGYSPDMDRESALRLVISSMTAALSRDAATGDGIDVVVIDDRGVNFLSREEISDLVREVLR
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta 1, 20S proteasome beta subunit 1, Proteasome core protein PsmB 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: POLG_RHDVB
Sequence: MAAMSRLTGMTTAILPEKKPLNFFLDLRDKTPPCCIRATGKLAWPVFPGQNGKEGPLKTCNKCGKWLNGFGYFGLEDLGDVCLCSIAQQKHKFGPVCLCNRAYIHDCGRWRRRSRFLKHYKALNKVIPCAYQFDESFSTPVFEGEVDDLFVELGAPTSMGFMDKKLLKKGKKLMDKFVDVDEPCLTSRDASLLDSIASDTTIRAKLEEEYGVEMVQAARDRKDFMKNLRLALDNRPANPVTWYTKLGNITEKGKQWAKKVVYGACKVTDPLKTLASILLVGLHNVIAVDTTVMLSTFKPVNLLAILMDWTNDLAGFVTTLVRLLELYGVVQATVNLIIEGVKSFWDKVVCATERCFDLLKRLFDTFEDSVPTGPTAGCLIFMAFVFSTVVGYLPNNSVITTFMKGAGKLTTFAGVIGAIRTLWITINQHMVAKDLTSIQQKVMTVVKMANEAATLDQLEIVSCLCSDLENTLTNRCTLPSYNQHLGILNASQKVISDLHTMVLGKINMTKQRPQPVAVIFKGAPGIGKTYLVHRIARDLGCQHPSTINFGLDHFDSYTGEEVAIADEFNTCGDGESWVELFIQMVNTNPCPLNCDKAENKNKVFNSKYLLCTTNSNMILNATHPRAGAFYRRVMIVEARNKAVESWQATRHGSKPGKSCYSKDMSHLTFQVYPHNMPAPGFVFVGDKLVKSQVAPREYKYSELLDLIKSEHPDVASFDGANRFNFVYPDAQYDQALLMWKQYFVMYGCVARLAKNFVDDIPYNQVHISRASDPKIEGCVEYQCKFQHLWRMVPQFVLGCVNMTNQLGTPLTQQQLDRITNGVEGVTVTTVNNILAFHSQTTLINPSFLKLIWAVRKHLKGLSGVTKVAQFIWRVMTNPVDAYGSLVRTLTGAATFSDEPVSTTIICSNCTIQIHSCGGLLVRYSRDPVPVASDNVDRGDQGVDVFTDPNLISGFSWRQIAHLFVEVISHLCANHLVNLATMAALGPVATKAFQGVKGKTKRGRGARVNLGNDEYDEWQAARREFVNAHDMTAEEYLAMKNKAAMGSDDQDSVMFRSWWTRRQLRPDEDQVTIVGRGGVRNEVIRTRVRQTPKGPKTLDDGGFYDNDYEGLPGFMRHNGSGWMIHIGNGLYISNTHTARSSCSEIVTCSPTTDLCLVKGEAIRSVAQIAEGTPVCDWKKSPISTYGIKKTLSDSTKIDVLAYDGCTQTTHGDCGLPLYDSSGKIVAIHTGKLLGFSKMCTLIDLTITKGVYETSNFFCGEPIDYRGITAHRLVGAEPRPPVSGTRYAKVPGVPDEYKTGYRPANLGRSDPDSDKSLMNIAVKNLQVYQQEPKLDKVDEFIERAAADVLGYLRFLTKGERQANLNFKAAFNTLDLSTSCGPFVPGKKIDHVKDGVMDQVLAKHLYKCWSVANSGKALHHIYACGLKDELRPLDKVREGKKRLLWGCDVGVAVCRAAVFHNICYKLKMVARFGPIAVGVDMTSRDVDVIINNLTSKASDFLCLDYSKWDSTMSPCVVRLAIDILADCCEQTELTKSVVLTLKSHPMTILDAMIVQTKRGLPSGMPFTSVINSICHWLLWSAAVYKSCAEIGLHCSNLYEDAPFYTYGDDGVYAMTPMMVSLLPAIIENLRDYGLSPTAADKTEFIDVCPLNKISFLKRTFELTDIGWVSKLDKSSILRQLEWSKTTSRHMMIEETYDLAKEERGVQLEELQVPAAAHGQEFFNFVCKELERQQAYTQFSVYSYDAARKILADRKRVVSVVPDDEFVNVMEGKARTAPQGEAAGTATTASVPGTTTDGLDPGVVATTSVVTAENSSASIATAGIGGPPQQVDQQETWRTNFYYNDVFTWSVADAPGSILYTVQHSPQNNPFTAVLSQMYAGWAGGMQFRFIVAGSGVFGGRLVAAVIPPGIEIGPGLEVRQFPHVVIDARSLEPVTITMPDLRPNMYHPTGDPGLVPTLVLSVYNNLINPFGGSTSAIQVTVETRPSEDFEFVMIRAPSSKTVDSISPAGLLTTPVLTGVGNDNRWNGQIVGLQPVPGGFSTCNRHWNLNGSTYGWSSPRFADIDHRRGSASYPGSNATNVLQFWYANAGSAVDNPISQVAPDGFPDMSFVPFNGPGIPAAGWVGFGAIWNSNSGAPNVTTVQAYELGFATGAPGNLQPTTNTSGAQTVAKSIYAVVTGTAQNPAGLFVMASGVISTPNANAITYTPQPDRIVTTPGTPAAAPVGKNTPIMFASVVRRTGDVNATAGSANGTQYGTGSQPLPVTIGLSLNNYSSALMPGQFFVWQLTFASGFMEIGLSVDGYFYAGTGASTTLIDLTELIDVRPVGPRPSKSTLVFNLGGTANGFSYV
What is the function of this protein?
Capsid protein VP60 self assembles to form an icosahedral capsid with a T=3 symmetry, about 35 nm in diameter, and consisting of 180 capsid proteins.  A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry.  The capsid encapsulate VP2 proteins and genomic or subgenomic RNA.  Attaches virion to target cells by binding histo-blood group antigens, inducing endocytosis of the viral particle.  Acidification of the endosome induces conformational change of capsid protein thereby injecting virus genomic RNA into host cytoplasm (By similarity).
What are the official names of this protein?
Genome polyprotein, p254.
What are the subcellular locations of this protein?
[Capsid protein VP60]: Virion. Host cytoplasm.
Protein: NU6M_MYTED
Sequence: MSVMIMCVSLMSVFSIVLIAKQPISLGLVLLSGSMIACVEIALEVSSLLGFLLFLTYVSGVMVLFLYVLSIYPNEVYRFNLEFVMIVSSCCAMMGLVGLMNYEYVEISGSIIFKVYGWSKGVKPMYPNSSRFAVCDVSGVVFVYKNHSAFAKSKMSSS
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion membrane; Multi-pass membrane protein.
Protein: RS4_YERE8
Sequence: MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQPPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGANLLQLLEGRLDNVVYRMGFGATRAESRQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAVKMEGVFKRIPERTDLSADINEHLIVELYSK
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
Protein: RSMH_CALS4
Sequence: MEYVHKSVLLKETIEHLNINPEGIYVDGTLGGGGHSEEILKRLTTGKLIAIDRDEEAILAAKERLKDYKNVIYIKDNFKNIKEILRNLGIEKVDGILLDLGVSSYQLEEVERGFSYMKDAPLDMRMDKTSPFSAYDVVNRYSEKELERVIREYGEEKWASRIAKFIVEERKKGDIKTTSQLVEIIKKAIPASARRTGPHPAKRTFQAIRIEVNEELKDLDRALEDMVEVLRGKGRIAVITFHSLEDRIVKNTFKKLENPCTCPPGLPCTCGKQPVIKIITKKPILPSKEEVEENPRSRSAKLRVAEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRAG1_HUMAN
Sequence: MHQTLCLNPESLKMSACSDFVEHIWKPGSCKNCFCLRSDHQLVAGPPQPRAGSLPPPPRLPPRPENCRLEDEGVNSSPYSKPTIAVKPTMMSSEASDVWTEANLSAEVSQVIWRRAPGKLPLPKQEDAPVVYLGSFRGVQKPAGPSTSPDGNSRCPPAYTMVGLHNLEPRGERNIAFHPVSFPEEKAVHKEKPSFPYQDRPSTQESFRQKLAAFAGTTSGCHQGPGPLRESLPSEDDSDQRCSPSGDSEGGEYCSILDCCPGSPVAKAASQTAGSRGRHGGRDCSPTCWEQGKCSGPAEQEKRGPSFPKECCSQGPTAHPSCLGPKKLSLTSEAAISSDGLSCGSGSGSGSGASSPFVPHLESDYCSLMKEPAPEKQQDPGCPGVTPSRCLGLTGEPQPPAHPREATQPEPIYAESTKRKKAAPVPSKSQAKIEHAAAAQGQGQVCTGNAWAQKAASGWGRDSPDPTPQVSATITVMAAHPEEDHRTIYLSSPDSAVGVQWPRGPVSQNSEVGEEETSAGQGLSSRESHAHSASESKPKERPAIPPKLSKSSPVGSPVSPSAGGPPVSPLADLSDGSSGGSSIGPQPPSQGPADPAPSCRTNGVAISDPSRCPQPAASSASEQRRPRFQAGTWSRQCRIEEEEEVEQELLSHSWGRETKNGPTDHSNSTTWHRLHPTDGSSGQNSKVGTGMSKSASFAFEFPKDRSGIETFSPPPPPPKSRHLLKMNKSSSDLEKVSQGSAESLSPSFRGVHVSFTTGSTDSLASDSRTCSDGGPSSELAHSPTNSGKKLFAPVPFPSGSTEDVSPSGPQQPPPLPQKKIVSRAASSPDGFFWTQGSPKPGTASPKLNLSHSETNVHDESHFSYSLSPGNRHHPVFSSSDPLEKAFKGSGHWLPAAGLAGNRGGCGSPGLQCKGAPSASSSQLSVSSQASTGSTQLQLHGLLSNISSKEGTYAKLGGLYTQSLARLVAKCEDLFMGGQKKELHFNENNWSLFKLTCNKPCCDSGDAIYYCATCSEDPGSTYAVKICKAPEPKTVSYCSPSVPVHFNIQQDCGHFVASVPSSMLSSPDAPKDPVPALPTHPPAQEQDCVVVITREVPHQTASDFVRDSAASHQAEPEAYERRVCFLLLQLCNGLEHLKEHGIIHRDLCLENLLLVHCTLQAGPGPAPAPAPAPAPAAAAPPCSSAAPPAGGTLSPAAGPASPEGPREKQLPRLIISNFLKAKQKPGGTPNLQQKKSQARLAPEIVSASQYRKFDEFQTGILIYELLHQPNPFEVRAQLRERDYRQEDLPPLPALSLYSPGLQQLAHLLLEADPIKRIRIGEAKRVLQCLLWGPRRELVQQPGTSEEALCGTLHNWIDMKRALMMMKFAEKAVDRRRGVELEDWLCCQYLASAEPGALLQSLKLLQLL
What is the function of this protein?
Catalytically inactive protein kinase that acts as a scaffold protein.  Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth (By similarity).  Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism (By similarity).  Acts as a critical coactivator of Notch signaling (By similarity).
What are the official names of this protein?
Inactive tyrosine-protein kinase PRAG1, PEAK1-related kinase-activating pseudokinase 1, Pragmin, Sugen kinase 223, SgK223.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Nucleus. Note=Colocalized with NOTCH1 in the nucleus.
Protein: SPEH_METM7
Sequence: MKQLGKHIILELWGCENQALDDQPGIEKMLVDAVKACGATLICVKTHKFSPQGVTGVAVLSESHISIHTWPELGYAAMDVFTCGEHVAPHDTIPEIQKFLKPEKIDVMDIKRGIIEVDEVKE
What is the function of this protein?
Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
What are the official names of this protein?
S-adenosylmethionine decarboxylase proenzyme, AdoMetDC, SAMDC.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.
Protein: CAPSD_BPMR2
Sequence: MEQTQKLKLNLQHFASNNVKPQVFNPDNVMMHEKKDGTLMNEFTTPILQEVMENSKIMQLGKYEPMEGTEKKFTFWADKPGAYWVGEGQKIETSKATWVNATMRAFKLGVILPVTKEFLNYTYSQFFEEMKPMIAEAFYKKFDEAGILNQGNNPFGKSIAQSIEKTNKVIKGDFTQDNIIDLEALLEDDELEANAFISKTQNRSLLRKIVDPETKERIYDRNSDSLDGLPVVNLKSSNLKRGELITGDFDKLIYGIPQLIEYKIDETAQLSTVKNEDGTPVNLFEQDMVAITCNYACSIAYR
What is the function of this protein?
Assembles to form an icosahedral capsid.
What are the official names of this protein?
Putative major capsid protein, Putative major head protein.
What is the protein family that this protein belongs to?
Belongs to the HK97 phage major capsid protein family.
What are the subcellular locations of this protein?
Virion. Note=Forms the icosahedral capsid shell.
Protein: RS8_HYPBU
Sequence: MVMLDTLANAMAAIVNAEMRAKPEVIIMPASKLIANVLRVMQREGYIGEFEYIDDGRWGKIRVRLLGRINKAGVIKPRFSVKYKDLIRMPDWLRKYLPSRDIGILIISTSQGVMSHREAIQRRIGGVLLAYVY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: ADD_CLOP1
Sequence: MNLLNLPKIELHCHLDGSLRVETAIELAKKEGVKLDSYEYDKVKELLVIPKECNSLEDYLNRFALPVKLLQRAENLERVAFELMEDASKENVKYIEIRFAPLLHLEKGMTQKEVIESVIKGIRKAEELYDIKGNLILSCLRHHSIDSVYEVIEEGKNFIGKGVVAIDLAGGELENFVKPYEEVMKLARKAGFRVTIHAGETGYGKNVRDAIELLGAERIGHGLFIFNDEEAYNLVKEKGVTLEMCPKSNIDTKGVNKYEEHPIYKYHKDNIKVNLSTDNRTVSNINLTEEFENVHKTFNIDFEDYKKIYLNSVEASFCSEELKEKLKLSIII
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.
What are the official names of this protein?
Adenosine deaminase, Adenosine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
Protein: AROA_ZYMMO
Sequence: MTRPVHACPLVSRKAPPLSGKVHVPGDKSISHRALMLSALAVGESFVEGLLEGEDVLATAEAMRSMGADIRKDEKGCWHIHGVGVGSLLQPQNALDMGNSGTSTRLLMGVVASHPITATFIGDASLSKRPMGRISTPLSLMGARFSAAEGNRLPMTVTGLYPAIPIEYRLPVASAQVKSAILLAGLNTPGITRVIEPVPTRDHSERMLKGYGANLSVEENDGVRIISIHGEAELKPQHIIVPGDPSSAAFLVVAGLIVPGSDLIVENVGLNPTRSGLYTMLKAMGGQIEYLNPREVGGEPVADLSVKYSHLKAIDVPPSIVPSMIDEFPILFIAAAMAEGKSTLQGLAELRVKESDRIAVMAEGLKALGVSLEEKEDGLIIEGSAGEGLGQKGKMVSIAAHLDHRIAMSFAVAGLVSEGGVTIDDRRPIMTSFPVFGQLFKELGAEFEMGLVK
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.