PharMolix/UniProtQA huggingface dataset:
Protein: ASD_ARATH
Sequence: MVKMGEVWTNTGSALASLVFIYTIFERFFPYRLREHFEPLAQSLIGFIYPYIQITFHEYSGERFKRSDVYDAIQSYLSKDSSSRAKKLTANTIKGNKSIILSMDDHEEITDEFQGVKVWWQSKKHQSESRAISFYPKADESRFYMLKFHRRDREVITKKYLNHVISEGKTIEVKNRERKLYSNNPSQNWSGYKQTKWSHVTFEHPATFDTLAMEYKKKEEIKNDLIKFSNSKDYYKKIGKAWKRGYLLFGPPGTGKSTMIAAMANLLEYDVYDLELTTVKDNTELRRLLIETSGKSIIVIEDIDCSLDLTGQRKQKKDEEEDEDETSPIEKQMKKDQGENKGSKVTLSGLLNFIDGLWSACGGERIIVFTTNFIDKLDPALIRKGRMDKHIEMSYCGFEAFKVLANNYLDAKEEDDNELFDEIKRLLEVEEIKMTPADVGENLLKKSEVETKEICLKRLIEALKEEKEEAKRRIEDEEKKKKEEEEIKRKKREEKKIKKEEKEEKEENETTMKD
What is the function of this protein?
Required to regulate morphology and anatomy during seed maturation.
What are the official names of this protein?
AAA-ATPase ASD, mitochondrial, AAA-ATPase 1, Protein ATPASE-IN-SEED-DEVELOPMENT.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family. BCS1 subfamily.
What are the subcellular locations of this protein?
Mitochondrion membrane; Single-pass membrane protein.
Protein: GTHB1_TRITC
Sequence: MQLVVMAAVLAVAGVGQGCRFGCHLTNISFPVDSCGITEFIYTTICAGHCYHEDPVYIGHDDWAEQKICNGDWTYEVKHLQGCPVAVTYPVARNCECTACNAGNTYCGHFHGYIPSCL
What is the function of this protein?
Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Gonadotropin subunit beta-1, GTH-I-beta, Gonadotropin beta-I chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit beta family.
What are the subcellular locations of this protein?
Secreted.
Protein: 104K_THEPA
Sequence: MKFLILLFNILCLFPVLAADNHGVGPQGASGVDPITFDINSNQTGPAFLTAVEMAGVKYLQVQHGSNVNIHRLVEGNVVIWENASTPLYTGAIVTNNDGPYMAYVEVLGDPNLQFFIKSGDAWVTLSEHEYLAKLQEIRQAVHIESVFSLNMAFQLENNKYEVETHAKNGANMVTFIPRNGHICKMVYHKNVRIYKATGNDTVTSVVGFFRGLRLLLINVFSIDDNGMMSNRYFQHVDDKYVPISQKNYETGIVKLKDYKHAYHPVDLDIKDIDYTMFHLADATYHEPCFKIIPNTGFCITKLFDGDQVLYESFNPLIHCINEVHIYDRNNGSIICLHLNYSPPSYKAYLVLKDTGWEATTHPLLEEKIEELQDQRACELDVNFISDKDLYVAALTNADLNYTMVTPRPHRDVIRVSDGSEVLWYYEGLDNFLVCAWIYVSDGVASLVHLRIKDRIPANNDIYVLKGDLYWTRITKIQFTQEIKRLVKKSKKKLAPITEEDSDKHDEPPEGPGASGLPPKAPGDKEGSEGHKGPSKGSDSSKEGKKPGSGKKPGPAREHKPSKIPTLSKKPSGPKDPKHPRDPKEPRKSKSPRTASPTRRPSPKLPQLSKLPKSTSPRSPPPPTRPSSPERPEGTKIIKTSKPPSPKPPFDPSFKEKFYDDYSKAASRSKETKTTVVLDESFESILKETLPETPGTPFTTPRPVPPKRPRTPESPFEPPKDPDSPSTSPSEFFTPPESKRTRFHETPADTPLPDVTAELFKEPDVTAETKSPDEAMKRPRSPSEYEDTSPGDYPSLPMKRHRLERLRLTTTEMETDPGRMAKDASGKPVKLKRSKSFDDLTTVELAPEPKASRIVVDDEGTEADDEETHPPEERQKTEVRRRRPPKKPSKSPRPSKPKKPKKPDSAYIPSILAILVVSLIVGIL
What are the official names of this protein?
104 kDa microneme/rhoptry antigen, p104.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor. Note=In microneme/rhoptry complexes.
Protein: ACATN_RAT
Sequence: MSPTISHKDNSRQRRSGMFGHALDMKSGPLPPGGWDDNHQDSVGGEGDREVLLGDVGPGDFPKAKRSYRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYFKNFGRRKSWLVPTQYILGIFMIYLSTQVDRLLGNIDGRTPDVVALTVTFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKETREASVVKEETQGITDTYKLLFSIIKMPAVLAFCLLILTSKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLLISKYTAGPQPLNIFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIIVLLSYALHQVTLYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPEAIELCKKLGGSCVTALDGYYVESIVCVLIGFGWWFFLGPKFKKLQDEGPSSWKCKRTN
What is the function of this protein?
Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides.  Negatively regulates BMP signaling (By similarity).
What are the official names of this protein?
Acetyl-coenzyme A transporter 1, AT-1, Acetyl-CoA transporter 1, Solute carrier family 33 member 1.
What is the protein family that this protein belongs to?
Belongs to the SLC33A transporter family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: PSBJ_IPOPU
Sequence: MADTTGRIPLWIIGTVTGLLVIGLIGIFFYGSYSGLGSSL
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein J, PSII-J.
What is the protein family that this protein belongs to?
Belongs to the PsbJ family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PAFA_ACIFD
Sequence: MPRLARRIYGIENEYGITCTQRGQRRLSPDEVARYLFRRVVSWGRSSNVFLENGARLYLDVGSHPEYATPECDSLSDLVAHDKAGERILESLAHSAEAKMREEGIRGDVFLLKNNTDSAGNSYGCHENYLTVRVDDLTRLVEVLIPFLVSRQIIAGAGKVLLTSRGPLYAVSQRAEHIWEGVSSATTRSRPIINTRDEPHADAERYRRLHVIVGDSNMSQWATYLKVGAMAIVLRLLEEEVVLRDLTLENPIRAIREIAHDTELERTVRLVNGRELTGLEIQEAYFERAERYHERIGLPADEARALDMWREALKALRANDHEALFGKVDWVTKLTLIEAFRARHQLPLSHPQVSLLDLQYHDISRERGLFARLEAKGRVPRIVDDETIERAVDEPPATTRAALRGRFIRAAKEAHRDYTVDWVHLKLNDQAQRTVMLKDPFASEDERVDRLLTSI
What is the function of this protein?
Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation.  This tagging system is termed pupylation.  The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.
What are the official names of this protein?
Pup--protein ligase, Proteasome accessory factor A, Pup-conjugating enzyme.
What is the protein family that this protein belongs to?
Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.
Protein: Y388_MYCPN
Sequence: MSNFFEKYINGFIETLDQIDAADFQRIQHDFDPNQFPYDWVVERVSDVKDYLLNPRDFSDVETFKSTMRAKIKHFYACYSSKIPFFLFTSFVLAIFNSVGQYVKYHCDLDFTNPDAVTIFFREKALND
What are the official names of this protein?
Uncharacterized protein MG269.1 homolog.
Protein: CYB_PARBE
Sequence: MTNIRKTHPLMKIVNNSFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFMETWNIGVLLLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIVAALAGVHLLFLHETGSNNPSGLSSDSDKIPFHPYYTIKDILGVLILILALSLLVLFSPDLLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLALVPFLHTSKQRSMMFRPISQCLFWLLVADLFTLTWIGGQPVEHPFIIIGQLASILYFMLILVLMPIASLVENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TAGL3_MOUSE
Sequence: MANRGPSYGLSREVQEKIEQKYDADLENKLVDWIILQCAEDIEHPPPGRAHFQKWLMDGTVLCKLINSLYPPGQEPIPKISESKMAFKQMEQISQFLKAAEVYGVRTTDIFQTVDLWEGKDMAAVQRTLMALGSVAVTKDDGCYRGEPSWFHRKAQQNRRGFSEEQLRQGQNVIGLQMGSNKGASQAGMTGYGMPRQIM
What are the official names of this protein?
Transgelin-3, Neuronal protein NP25.
What is the protein family that this protein belongs to?
Belongs to the calponin family.
Protein: RL17_AEDAL
Sequence: MGRYAKEPDNPAKSCKARGSNLRVHFKNTRETALAIKRMPLRRAQKFLKNVCEKKECVPFRRFNGGVGRCAQAKHWNTSVGRWPKKSAEFLLQLLKNAEANADYRGLDVDRLVVDHIQVNRAPCLRRRTYRAHGRINPYMSSPCHIELSLTEKEDVVSKAAENEPAKKKLSKKKLQRQKEKMMRNE
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: PANK4_MOUSE
Sequence: MAERGASGGGSGGDSLDKSITLPPDEIFRNLENAKRFAIDIGGSLTKLAYYSTVQHKVAKVRSFDHPGKDVEQDHEPPYEISVQEEITARLHFIKFENTYMEACLDFIRDHLVNTETKVIQATGGGAYKFKDLIEEKLRLKVDKEDVMTCLIKGCNFVLKNIPHEAFMYQKDSDPEFRFQTNHPNIFPYLLVNIGSGVSIVKVETEDRFEWIGGSSIGGGTFWGLGALLTKTKKFDELLQLASRGRHANVDMLVQDIYGGAHQTLGLSGNLIASSFGKSATADREFSKEDMAKSLLHMISNDIGQLACLYAKLHGLDRVYFGGFFIRGHPVTMRTITYSINFFSKGEVQALFLRHEGYLGAIGAFLKGAEQDNPNQYSWGENYAASSGLMSTSPELCPTQRARSGTFDLLEMDRLERPLVNLPLLLDPSSYVPDTVDLTDDALARQYWLTCFEEALDGVVKRAVASQPESMDAVERAEKFRQKYWGKLQTLRHQPFAYGTLTVRSLLDTREHCLNEFNFPDPYSKVKQKENGLALKCFQSVTRSLDSLGWEERQLALVKGLLAGNVFDWGAKAVSDVLESDPQFGFEEAKRKLQERPWLVDSYTKWLQRLKGPPHKCALIFADNSGIDIILGVFPFVRELLFRGTEVILACNSGPALNDVTYSESLIVAERIAAMDPIICTALREDRLLLVQTGSSSPCLDLSLCTSRTTTCMVLPFAMWVLWTKLKSLVEKCLSPLSILLACSVLSAKSRLDKGLAVLVRERGADLVVIEGMGRAIHTNYHALLRCESLKLAVVKNAWLAERLGGQLFSVIFKYEVPTK
What is the function of this protein?
Phosphatase which shows a preference for 4'-phosphopantetheine and its oxidatively damaged forms (sulfonate or S-sulfonate), providing strong indirect evidence that the phosphatase activity pre-empts damage in the coenzyme A (CoA) pathway.  Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms.  Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein.  May play a role in the physiological regulation of CoA intracellular levels.
What are the official names of this protein?
4'-phosphopantetheine phosphatase, Inactive pantothenic acid kinase 4, mPanK4.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the damage-control phosphatase family. Phosphopantetheine phosphatase II subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAX_CLOK5
Sequence: MILVLDVGNTNIVLGVYDDRELISVWRLSTDSKRTADEYGVQVIDLFLQSKLKPEDITGSIISSVVPTIMYSLEHMIIKYFQVSPIIVGPGVKTGINVKYDNPREVGADRIVNAVAAHEIYNRSLIIIDFGTATTFCAVTSAGDYLGGAICPGIKISSSALFEMAAKLPRVEIIRPQNIIGKNTVSSMQSGIVYGYIGQVDYIVKKMKMEMMDLGEEEPLVIATGGLAKLINEGTKSIDIIDSVLTLTGLRLIYEKNKE
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGB_PORPU
Sequence: MLTNTERVKVLSDVTILQKFSSRIIVIKYGGAAMKNQKLKDHVISDLVFLSFIGLRPILVHGGGPEINFWLDQLKILPKFENGVRVTDQPTMDIVEMVLVGRVNKDLVASINKQGGKSVGLSGKDGLLITSRPSDKPNLGFVGEVQNVDTNLLEILINNNYIPVIASVAADKQGQSYNINADTVAGEIAARLNAEKLILLTDTPGILRNASDATTLISHLSIQEARDLTKTAVISGGMIPKVNCCIRSLAQGVASAHILDGRIDHALLLEILTDQGIGSMLVV
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
What are the official names of this protein?
Acetylglutamate kinase, N-acetyl-L-glutamate 5-phosphotransferase, NAG kinase, NAGK.
What is the protein family that this protein belongs to?
Belongs to the acetylglutamate kinase family. ArgB subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: EFG_CAMHC
Sequence: MARKTPLHMVRNIGIAAHIDAGKTTTSERILFFTGISHKIGETHEGTATMDWMDQEKERGITITSAATTCFWRDHQINLIDTPGHVDFTIEVERSMRVLDGAVAVFCSVGGVQPQSETVWRQANKYHVPRIAFVNKMDRVGANFYNVEKQIKDRLKANPVPLQIPIGAEDNFKGVVDLIQMKALVWESDEPTNYVVKDIPADLQDKAKEYHDKLVEAVAETDEKLMEKFFDGVELSIDEIKKGIKTATLSLNIVPMLCGTAFKNKGVQPLLDAVVDYLPAPDEVPNIKGQYENGKEVSVESTDDGEFAALGFKIATDPFVGQLTFVRVYRGVLASGSYVYNAGKGKKERVGRILRMHSNKREEIKELYAGEIGAVVGLKDTLTGDTLASEKDPVILERMEFPDPVISVAVEPKTKADQEKMGIALQKLAQEDPSFRVATDEESGQTIISGMGELHLEIIVDRMLREFKVEAEVGKPQVAYRETIRKTVEQEYKYAKQSGGRGQYGHVFLRLEPMEPGGENYEFVNDIKGGAVPKEYIPAVDKGCQEAMQSGVLAGYPVVDIKVTLFDGSYHEVDSSEMAFKLAASMGFKEGARKANAVILEPMMKVEVETPEEYMGDVIGDLNKRRGQVNNMSDRGGNKIIDAFCPLAEMFGYSTDLRSQTQGRATYSMEFDHYDEVPRNVSEEIIKKRNG
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G, EF-G.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: F16P2_SACHY
Sequence: MDHAADAHRTDLMTITRHVLNEQSRNPESRGDFTILLSHIVLGCKFVASAVNKAGLAQLIGLAGETNVQGEEQKKLDVLSNEVFVKALVSSGRTCVLVSEEDEETTFVDPKLRGKYCVCFDPLDGSSNIDCGVSIGTIFGIYMIKDKDNVTLSDVLQPGKDMLAAGYCMYGSSCTLVLSTGTGVNGFTLDPSLGEFILTHPDIKIPKKGKIYSVNEGNAKNWDVPVAKFVEKCKYPKDGSPPKSLRYIGSMVADVHRTLLYGGVFLYPADQKSPNGKLRVLYEVFPMSFLMEQAGGQSFTGKERALDLVPTKIHERSPIFLGSYDDVEEIKALYAEQAKSSSA
What are the official names of this protein?
Fructose-1,6-bisphosphatase, cytosolic, FBPase, D-fructose-1,6-bisphosphate 1-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EIF2A_SCHPO
Sequence: MSQKSQFAYRSSKSIGLVNASENYASPPKFEAISEPARNACYSPNGKLFAYATATQVVINDTESGAKLTQLPAANTYELGFSPLGKYLSTWERPGKEADGTPKQNMKVWNTETGQLVFSFVQRNQTGWNLQYTCDESLAARLVTNEVHFYETGNMSKGPIAKLRVEGISDFALSPGQNHAVAVFIPEKKGAPASVRTYSIPNFNSPLSQKTFFKADKVQFKWNALGTSLLVLTQTEVDKSNKNYYGETNLYLLGITGQFDCRVDLDREGPIHDVCWNADSKEFGIVYGYMPAKTAIFDNRANVVSIIPPAPRNTLIFSPNSRYILLAGFGNLQGSIDIFDAANNMKKITTVEAANCTYCEFSPDSQFLLTAVTSPRLRVDNSIKIWHITGAPMFYEEFNELYQAFWRPRPLNPTLLQNALTSASLPSPPTPHASASKLAAKPSVKPAGAYRPPGARGQNSTFSYRREEIDVMSSGSANKHVNSSRQRVVPGATPVIDGNKKNNKKTKPAVKQVAQPTAEVSDEKKIRSLCKKLRAIDDLKSRLNNNEKLEATQVKKIESEGKVLAELKALGWTPDA
What is the function of this protein?
Functions in the early steps of protein synthesis of a small number of specific mRNAs.  Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits.  In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.
What are the official names of this protein?
Eukaryotic translation initiation factor 2A, eIF-2A.
What is the protein family that this protein belongs to?
Belongs to the WD repeat EIF2A family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TOXPH_AMAPH
Sequence: RVFHLFDYPPLNTGDLQLKAKIKPFIFTSNNSFLSYNDVTVKHNDVPAGDPFKASAVIKDTNPNPYIAAGVTAILNDVLGRFAVPLMNDLKTGKTDGWDLMMKYDKHSTRSYMALAYTPSDHLNLPKKPLPTDVINWLETFDK
What is the function of this protein?
Cytotoxic L-amino acid oxidase with high oxidase activity towards DL-methionine and L-methionine, L-phenylalanine, DL-norleucine, L-isoleucine, L-arginine, L-tyrosine, and DL-leucine.  Shows relatively low activity towards DL-lysine and L-lysine, DL-asparagine, DL-valine, L-histidine, DL-threonine, DL-thryptophane, and L-glutamic acid; and no activity towards L-cysteine, L-glycine, L-proline, L-oxyproline, DL-serine, and DL-aspartic acid.  Does not use benzylamine, ethanolamine, diethylamine, meta- and para-phenylendiamine, ortho-, meta- and para-aminophenols, or putrescin as a substrate.  Acts as a toxin by inducing chromatin condensation, as well as DNA and nucleus fragmentation, which are typical for apoptosis (PubMed:20121947).  Probably induces cell damage indirectly via the generation of free radicals and oxidant agents that can trigger cell impairment and apoptosis by a caspase-independent pathway (PubMed:20121947).
What are the official names of this protein?
Cytotoxic L-amino-acid oxidase, Toxophallin.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
Protein: HIS4_CHLSY
Sequence: MEIIPAIDIKDGRCVRLYQGDFAQMTVYADDPVAVARSWEAQGATRLHLVDLDGARAGHPQNVDAILAITQAVQIPVQLGGGLRREQDVESALALGVERVIIGTAAIAETDLVARLLDRFGEQIVIGIDARNGLVATDGWTVTSSVKATVLAEQMANLGARRIIYTDISRDGALSGPNFAALSELITPHGPAIIASGGIASIDHVRQLAQLGVEGAIIGKALYVGAVKLAEAMAVAHMTNV
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAT_PSYWF
Sequence: MTSQKIVKRLGKTSIVPPHGSDELKPLLLEGEALSQALHNAKNLPKITLSSRERGDLIMLGIGGFTPLDGFMNQADWQGVVDEMTLKTGANKGLFWPIPITLSTSKEQADSLAPGDEVALVAEDGEIMGVITVEETYTIDKAHECQQVFTTTEEEHPGVKQVMEQGEVNVAGAVKVFSQGEFPTLYPEIYKTPAETRKLFEEKNWQTIAAFQTRNPMHRSHEYLAKIAIEICDGVMIHSLLGALKPGDIPAEVRQEAIKTLIDNYFKKDTVIQAGYPLDMRYAGPREALLHALFRQNYGCSHLIVGRDHAGVGDYYGPFDAQAIFDEIDKDAMLTQPLKIDWTFWCNACQAMASTKTCPHDAEHHVKVSGTKLRKALSEDQEVPENFSRPEVLQILRNYYESIAKEDRAEVKLVGASAQ
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: TGM1_RAT
Sequence: MEGPRSDVGRWGRSPWQPTTPSPEPEPEPEPDRSSRSRRGGGRSFWARCCGCCSCGNRADDDWGPEPSGSRSRGTSSRGGGSRGGDSRGRDSRGGRRPESRGSGVNAAGDGTIREGMLVVNGVDLLCSRSDQNRREHHTDEFEYDELILRRGQPFHIILFLNREYESSDRIALELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVTKTNGHNLTLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAINSNMREDITHIYKHPEGSEAERKAVEKAAAHGSKPNVYATRDSAEDVAMQVEAQDAVMGQDLTVSVVLTNRGSSRRTVKLHLYLCVTYYTGVSGPTFKETKKEVVLAPGASDTVAMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPITLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPSSGGRGFSEAVGDSRSGENIPMAFRGGA
What is the function of this protein?
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.  Responsible for cross-linking epidermal proteins during formation of the stratum corneum.  Involved in cell proliferation (By similarity).
What are the official names of this protein?
Protein-glutamine gamma-glutamyltransferase K, Epidermal TGase, Transglutaminase K, TG(K), TGK, TGase K, Transglutaminase-1, TGase-1.
What is the protein family that this protein belongs to?
Belongs to the transglutaminase superfamily. Transglutaminase family.
What are the subcellular locations of this protein?
Membrane; Lipid- anchor.
Protein: VEXIN_PONAB
Sequence: MMHQIYSCSDENIEVFTTVIPSKVSSPARRRAKSSQHLLTKNVVIESDLYTHQPLELLPHRGDRRDPGDGRRFGRLQTARPPTAHPAKASARPVGISEPKTSNLCGNRAYGKSLIPPVPRISVKTSASASLEATAMGTEKGAVLMRGSRHLKKMTEEYPALPQGAEASLPLTGSASCGVPGILRKMWTRHKKKSEYVGATNSAFEAD
What is the function of this protein?
Required for neurogenesis in the neural plate and retina.  Strongly cooperates with neural bHLH factors to promote neurogenesis.
What are the official names of this protein?
Vexin.
What is the protein family that this protein belongs to?
Belongs to the vexin family.
What are the subcellular locations of this protein?
Cell membrane. Nucleus. Note=Nuclear localization is essential for its function in neurogenesis.
Protein: RL11_KARMG
Sequence: MLKTIKKIIKLQIKGGLANPAPPIGPALGSAGVNIMDFCKQYNFSTQKSKGKLLPVIITIYNDKSFSFIIKEPPVSKQLLELCKLDKGSKESNKIKVGKITLAKIESIAKNKIIDMNCFNIKSAISMVAGTARSMGIEIL
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: CH60_SHEPA
Sequence: MAAKEVLFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLDKSFGAPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVTEGLKAVAAGMNPMDLKRGIDKAVVAAVAELKNLSQECSDTKAIAQVGTISANSDESIGEIIATAMERVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELESPFILLVDKKVSNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDIAILTGGTVIAEEIGLELEKATLEDLGTAKRVIITKDDTTIIDGNGEETQIKARVAQIKIQAEESTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVAGGGVALVRVASKIGELDVINEDQKHGVIIALRAMEAPLRQIAANAGEEGSVVANNVKNGTGNYGYNAGNDTYGDMLEMGILDPTKVTRSALQFASSIAGLMITTECMVAEVKEDAADMGGMGGMGGMGGMGGMM
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: P4H_MIMIV
Sequence: MKTVTIITIIVVIIVVILIIMVLSKSCVSHFRNVGSLNSRDVNLKDDFSYANIDDPYNKPFVLNNLINPTKCQEIMQFANGKLFDSQVLSGTDKNIRNSQQMWISKNNPMVKPIFENICRQFNVPFDNAEDLQVVRYLPNQYYNEHHDSCCDSSKQCSEFIERGGQRILTVLIYLNNEFSDGHTYFPNLNQKFKPKTGDALVFYPLANNSNKCHPYSLHAGMPVTSGEKWIANLWFRERKFS
What is the function of this protein?
May catalyze the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in the 6 collagen-like proteins of Mimivirus.
What are the official names of this protein?
Putative prolyl 4-hydroxylase, 4-PH, Procollagen-proline,2-oxoglutarate-4-dioxygenase.
What is the protein family that this protein belongs to?
Belongs to the P4HA family.
What are the subcellular locations of this protein?
Virion.
Protein: LRC32_HUMAN
Sequence: MRPQILLLLALLTLGLAAQHQDKVPCKMVDKKVSCQVLGLLQVPSVLPPDTETLDLSGNQLRSILASPLGFYTALRHLDLSTNEISFLQPGAFQALTHLEHLSLAHNRLAMATALSAGGLGPLPRVTSLDLSGNSLYSGLLERLLGEAPSLHTLSLAENSLTRLTRHTFRDMPALEQLDLHSNVLMDIEDGAFEGLPRLTHLNLSRNSLTCISDFSLQQLRVLDLSCNSIEAFQTASQPQAEFQLTWLDLRENKLLHFPDLAALPRLIYLNLSNNLIRLPTGPPQDSKGIHAPSEGWSALPLSAPSGNASGRPLSQLLNLDLSYNEIELIPDSFLEHLTSLCFLNLSRNCLRTFEARRLGSLPCLMLLDLSHNALETLELGARALGSLRTLLLQGNALRDLPPYTFANLASLQRLNLQGNRVSPCGGPDEPGPSGCVAFSGITSLRSLSLVDNEIELLRAGAFLHTPLTELDLSSNPGLEVATGALGGLEASLEVLALQGNGLMVLQVDLPCFICLKRLNLAENRLSHLPAWTQAVSLEVLDLRNNSFSLLPGSAMGGLETSLRRLYLQGNPLSCCGNGWLAAQLHQGRVDVDATQDLICRFSSQEEVSLSHVRPEDCEKGGLKNINLIIILTFILVSAILLTTLAACCCVRRQKFNQQYKA
What is the function of this protein?
Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19750484, PubMed:19651619, PubMed:22278742).  Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (PubMed:22278742).  Able to outcompete LTBP1 for binding to LAP regulatory chain of TGF-beta (PubMed:22278742).  Controls activation of TGF-beta-1 (TGFB1) on the surface of activated regulatory T-cells (Tregs) (PubMed:19750484, PubMed:19651619).  Required for epithelial fusion during palate development by regulating activation of TGF-beta-3 (TGFB3) (By similarity).
What are the official names of this protein?
Transforming growth factor beta activator LRRC32, Garpin, Glycoprotein A repetitions predominant, GARP, Leucine-rich repeat-containing protein 32.
What is the protein family that this protein belongs to?
Belongs to the LRRC32/LRRC33 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell surface.