PharMolix/UniProtQA huggingface dataset:
Protein: RIMO_CLOD6
Sequence: MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIVNTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVGTGSYQNIDKILKELSEIHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCTYCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELLEELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRKTTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAYSREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDNVYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CYB_BALAC
Sequence: MTNIRKTHPLMKIINDAFIDLPTPSNISSWWNFGSLLGLCLIVQILTGLFLAMHYTPDTTTAFSSVTHICRDVNYGWIIRYLHANGASMFFICLYAHMGAGLYYGSHAFRETWNIGVILLFTIMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAIVHLIFLHETGSNNPTGIPSDMDKIPFHPYYTIKDILGALLLILTLLALTLFAPDLLGDPDNYTPANPLSTPAHIKPEWYFLFAYAILRSIPNKLGGVLALLLSILILAFIPMLHTSKQRSMMFRPFSQSLFWVLVADLLTLTWIGGQPVEHPYMIVGQLASILYFLLILVLMPVASLIENKLMKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SKP1B_ARATH
Sequence: MSTVRKITLKSSDGENFEIDEAVALESQTIKHMIEDDCTDNGIPLPNVTSKILSKVIEYCKRHVEAAEKSETTADAAAATTTTTVASGSSDEDLKTWDSEFIKVDQGTLFDLILAANYLNIKGLLDLTCQTVADMIKGKTPEEIRKTFNIKNDFTPEEEEEVRRENQWAFE
What is the function of this protein?
Involved in ubiquitination and subsequent proteasomal degradation of target proteins.  Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex.  The functional specificity of this complex depends on the type of F-box protein.  In the SCF complex, it serves as an adapter that links the F-box protein to CUL1.  SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis.  SCF(TIR1) is involved in auxin signaling pathway.  SCF(COI1) regulates responses to jasmonates.  SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling.  SCF(ADO1), SCF(ADO2), SCF(ADO3) are related to the circadian clock.  SCF(ORE9) seems to be involved in senescence.  SCF(EBF1/EBF2) may regulate ethylene signaling.  Plays a role during embryogenesis and early postembryonic development, especially during cell elongation and division.  Contributes to the correct chromosome segregation during tetrad formation.
What are the official names of this protein?
SKP1-like protein 1B, SKP1-like 2, UFO-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the SKP1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: TTF1_HUMAN
Sequence: MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLEKMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQGRWII
What is the function of this protein?
Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin.  Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription.  Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
What are the official names of this protein?
Transcription termination factor 1, TTF-1, RNA polymerase I termination factor, Transcription termination factor I, TTF-I.
What are the subcellular locations of this protein?
Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Note=May be localized to the nucleolus in an NPM1/B23-dependent manner. May be displaced from the nucleolus into the nucleoplasm in an CDKN2A/ARF-dependent manner. May shuttle back and forth from nucleoplasm to nucleolus.
Protein: EFTU_BURTA
Sequence: MAKEKFERTKPHVNVGTIGHVDHGKTTLTAAIATVLSAKFGGEAKKYDEIDAAPEEKARGITINTAHIEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLARQVGVPYIIVFLNKCDMVDDAELLELVEMEVRELLSKYDFPGDDTPIIKGSAKLALEGDKGELGEVAIMNLADALDTYIPTPERAVDGAFLMPVEDVFSISGRGTVVTGRVERGVIKVGEEIEIVGIKATAKTTCTGVEMFRKLLDQGQAGDNVGILLRGTKREDVERGQVLAKPGSITPHTHFTAEVYVLSKDEGGRHTPFFNNYRPQFYFRTTDVTGSIELPKDKEMVMPGDNVSITVKLIAPIAMEEGLRFAIREGGRTVGAGVVAKIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSL_BUCBP
Sequence: MNKNYNLSKIIFNDLISFYKTQLILIFMIFISALLIITIIHKTRLLTSQQEELDIIKKKQMPLNLEKYISTSRLKFKHEKIDT
What is the function of this protein?
Essential cell division protein.
What are the official names of this protein?
Cell division protein FtsL.
What is the protein family that this protein belongs to?
Belongs to the FtsL family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type II membrane protein. Note=Localizes to the division septum where it forms a ring structure.
Protein: GAR1B_HUMAN
Sequence: MLSSFPHRKTWRKSKKTVKVTRSYPTFPSLNAWEEFRGLLPVDGEPNPGAGLGVEEGLLCRVVHSPEFNLFLDSVVFESNFIQVKRGRNWRDVYKASNTMALGVTSSVPCLPLPNILLMASVKWHQGQNQTWNRPSIAPNIFLKRILPLRFVELQVCDHYQRILQLRTVTEKIYYLKLHPDHPETVFHFWIRLVQILQKGLSITTKDPRILVTHCLVPKNCSSPSGDSKLVQKKLQASQPSESLIQLMTKGESEALSQIFADLHQQNQLSFRSSRKVETNKNSSGKDSSREDSIPCTCDLRWRASFTYGEWERENPSGLQPLSLLSTLAASTGPQLAPPIGNSI
What is the function of this protein?
RAB2B effector protein required for accurate acrosome formation and normal male fertility.  In complex with RAB2A/RAB2B, seems to suppress excessive vesicle trafficking during acrosome formation.
What are the official names of this protein?
Golgi-associated RAB2 interactor protein 1B, Testis development protein NYD-SP18.
What is the protein family that this protein belongs to?
Belongs to the GARIN family.
What are the subcellular locations of this protein?
Golgi apparatus.
Protein: WSB2_MOUSE
Sequence: MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCVVKLVPWPLEEQFIPKGFEAKSRSSKNDPKGRGSLKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQAPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGERLRSLHHTQLEPTMDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRIWALELKAPVAFAPMTNGLCCTFFPHGGIIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
WD repeat and SOCS box-containing protein 2, WSB-2, SOCS box-containing WD protein SWiP-2.
Protein: CU01_LONON
Sequence: MRFLIAFVAILGYASASAIYPLAYGVNAGDAQAAAIDAAVAAQDHARAANEGQARAVEAAVQYNTDATRQVAEANRDLHETAYWNGVAATQNAVAAAQSQVAAANGAAAAVRAAHESGAYVTPYVAPYAGSYVNPYAASLVTPYGYGINGLGAVGSWCLRSRRLPCRCPRLVNT
What are the official names of this protein?
Cuticle protein 1, Lipocalin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: REP6_SCSVF
Sequence: MPTRQSTSWVFTLNFEGEIPILPFNESVQYACWQHERVGHDHLQGFIQFKSRNTTLRQAKYIFNGLNPHLEIARDVEKAQLYAMKEDSRVAGPWEYGLFIKRGSHKRKLMERFEEDGEEMKIADPSLYRRCLSRKMAEEQRCSSEWNYDLRPWQEEVMHLLEEEPDYRTIIWVYGPAGNEGKSTFARHLSLKDGWGYLPGGKTQDMMHLVTAEPKNNWVFDIPRVSSEYVNYGVIEQVKNRVMVNTKYEPCVMRDDNHPVHVIVFANVLPDLGKLSEDRIKLIRC
What is the function of this protein?
Initiates and terminates the replication only of its own subviral DNA molecule.  The closed circular ssDNA genome is first converted to a superhelical dsDNA.  Rep binds a specific hairpin at the genome origin of replication.  Introduces an endonucleolytic nick within the intergenic region of the genome, thereby initiating the rolling circle replication (RCR).  Following cleavage, binds covalently to the 5'-phosphate of DNA as a tyrosyl ester.  The cleavage gives rise to a free 3'-OH that serves as a primer for the cellular DNA polymerase.  The polymerase synthesizes the (+) strand DNA by rolling circle mechanism.  After one round of replication, a Rep-catalyzed nucleotidyl transfer reaction releases a circular single-stranded virus genome, thereby terminating the replication.  Displays origin-specific DNA cleavage, nucleotidyl transferase, ATPase and helicase activities (By similarity).
What are the official names of this protein?
Para-Rep C6, Rep6, Replication-associated protein of non-essential DNA C6.
What is the protein family that this protein belongs to?
Belongs to the nanoviridea/circoviridae replication-associated protein family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: TBC11_CAEEL
Sequence: MEDFKDFTEVTQFTNVQYLGCSQLVNNDNDNEMKALMKVLDEQKGAQTINVTLVVPHNISGTVKLIDAQGKVLSSFSLVNIRFCIRGESSTSQNNCFGISFTHKISVGEHNSSDILHQCHVFRTSKAETAAKALYSFSYAFSNKNVSSESNRLEFQFESILEVKENDGTVEKPSWKLCPQHNGVFKVRRDREKKIVVQLRQIDGFLLNIKKCFGMLLAAGRNLRHSDLQLLEMDRNATGTDSAVFVIEANWDPRVHMFEVLNTETPRDTRVFMTVAIDVIVSEISEPIRFSMEAMSRVFHEHERFYKTPQTVVSEEFTLVLEKSCDQSDPNDRKLTFISLESDSDRKRSKQNLGKSPSRMPTQLLHPTGDDESDCDEPLLSGSGKVSQECKEEHLEMWDQLIENWDQQSDRPQKISELVLDGIPDKLRGRVWQLLSNVRILAIDQPDLVEKYHIFLSQPCPSEQVIMRDIHRTFPAHDYFKESQGKGQQSLYKISKVYSLYDEEVSYCQGLSFLAASLLLHMPEEQAFCTLVKIMFNYGLRDLFKLGFDNLHLRFFQLTALLKDYIPDLSHHLEHIGIETHMYASQWFLTLFTAKFPLQMVFFILDLFLSQGMNTIFHISLALLDDAKTDLLQLDFEGTLKYFRVSLPRKYRTEASTKCLIHKAVKFRLNHSKLEVYENEYKRIKELERENEDPVLRMEKEIGRHQANTLRLERENDDLAHELVTSKIELRRKLDVAEDQIETSANAIERLTRQNMDILEENKNLMREYEQIKEMYRRDVLRLEENGSRAEKLLAEYKKLFSERSKRAENEREHFEVQKKAIIARISDCDKCWPAVCEWEKNRSPVHSASTPTGPDLLTKLEEREDHIKNLEIDLAQTKLSLVEAECRNQDLTHQLMAQSESDGKKWFKKTITQLKEVGSSLKHHERSNSSVTP
What is the function of this protein?
Rab GTPase activating protein for the small GTPases rab-6. 1 and rab-6. 2 (Probable).  Probably acts through rab-6. 1 and rab-6. 2 to play a role in microRNA-mediated gene silencing in different tissue types (PubMed:33826611).  Required for seam cell division and alae formation (PubMed:33826611).
What are the official names of this protein?
Rab GTPase-activating protein tbc-11, RabGAP tbc-11, TBC1 domain family member 11.
Protein: NUOD_BRUC2
Sequence: MAETQVRNFNINFGPQHPAAHGVLRLVLELDGEVVERVDPHIGLLHRGTEKLMEAKTYLQAVPYLDRLDYVAPMNQEHAYALAVERLLDIEVPKRGQLIRVLYSEIGRILNHLLNVTTQAMDVGALTPPLWGFEEREKLMVFYERACGARMHAAYFRPGGVHQDLPDQLIEDIGKWIDPFFTTLKNLDDLITPNRIFKQRNVDIGVVKLEDAWAWGFSGVMVRGSGAAWDLRKSQPYECYSEMEFDIPVGKNGDCYDRYLIRMEEMRQSARIMRQCVDLLLGKERVGPVSNTDHKIVPPKRGEMKRSMEALIHHFKLYTEGYHVPAGEVYAAVEAPKGEFGVYLVSDGSNKPYRCKLRAPGFAHLQAMDFLCRGHMLADVSAILGSLDIVFGEVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit D, NADH dehydrogenase I subunit D, NDH-1 subunit D.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: MDLA_BUCAP
Sequence: MRLFNQLKWYFIKEWKRYLGSIILLIIIAFLQLLPPKIIGILIDLIIKEKMSGFEILPWISIILLIAIIVYILRYLWRILLFGASYQLATELRVKFYSYLSKQSEIFFLKNRTGDLIARATNDVDRVVFAAGEGVLTLVDSSVMGISVLIVMITQISWLLTIISLIPMPIMAILIKKYGKKLHDTFRNAQSAFSLLNNQTQEILTSIRMIRAFGLEKNQLKKFNNIVNDTGKKNMEVAEIDARFDPVIYLSVAFSNLLAITAGGWLVWNNTITIGKLTSFIMYLGLMIWPMLALAWMFNIVERGSAAWDRIHSIINQNLYIEDGKKTIINMNGKLNINIDMFFYPKNKKPSLKNIYLSLNPGKTLGICGPTGAGKSTLLKLIQRQFKIHKGEILYNSSSLLELKIDYWRSKIGVVNQTSFLFSDSISNNISLGKPKASQKEIEKAAKLADIHKDIVCLPQGYNTQVGERGVMLSGGQKQRIAIARALLLNTEILILDDALSAVDGKTENNILKNLKKWKDKGYSLIIVAHRLSALIHADEIIVIKEGTIIQRGNHEKLIKEKNWYKSMYDHQKIQTEIENF
What are the official names of this protein?
Multidrug resistance-like ATP-binding protein MdlA.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Drug exporter-2 (TC 3.A.1.117) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NRFA_SHEPC
Sequence: MMKKMTGKSFALSALVAASFMAAGAMASDKTEPRNEVYKDKFKNQYNSWHDTAKSEELVDALEQDPNMVILWAGYPFAKDYKAPRGHMYAVTDVRNTLRTGAPKDAEDGPLPMACWSCKSPDVPRLIEEQGEDGYFKGKWAKGGPEVTNAIGCGDCHDKGSPKLRISRPYVDRALDAIGTPFSKASKQDKESMVCAQCHVEYYFEKTEDKKGFVKFPWDMGVTVEKMEVYYDSIQFSDWTHALSKAPMLKAQHPEYETWKMGIHGMNNVSCVDCHMPKVTSADGKKFTDHKVGNPFDRFEETCATCHSQTKEFLVGVTNERKAKVKEMKLKAEEQLVKAHFEAEAAWKAGATEEEMKPILTDIRHSQWRWDLAIASHGVAAHAPDEALRILGTSVNKAADARVKLAQLLGKKGITDPVAVPDISTKAKAQAVLGMDMKQLVEEKEAFKKNILPKWDEEAKKREATYK
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: SMXL5_ARATH
Sequence: MRTGGYTIQQTLTTEAASVLKHSLTLARRRGHAQVTPLHVAATLLSSRTSLLRRACIKSHPGFSTNYQFAPSRLQHHHHHNQNHPLQCRALELCFNVALNRLPTVPGPMFHGQPSLANALVAALKRAQAHQRRGCIEQQQQTQTHPQTQQTQLLAVKVELEQLVISILDDPSVSRVMREAGFNSTAVKSCVEDCSVSSVFYGGSAVGVFSSPNSPDQQQQHHNSINRLHHYQNPKDFNFINPNFPLWQTHFLNQSPDQNPLLLSSSASHHHQQQRLREIDLKLVVDVLMRKKTKKKNPVIVGDSISFTEGFVSELMAKLERGEIDQTGELKQTHFVKFHFSPMASKFMRREDVELNIKELRKKVLSLTTSGKNAIIFTGDLKWTVKEITNNNSGGINEISSSYSPLDHLVEEIGKLITECNDDGDDDDCKTRKVWVMGTASFQTYMRCQMRQPSLETLWALHPVSVPSSANLGLSLHATSGHEARNMSTVNATKSLSGYDKAEEEETISHVLSCCPECVTSFDREAKSLKANQDKLLPSWLQSHDADSSSQKDELMGLKRKWNRFCETLHNQTGQLSMMGNYPYGLPYGSSHESSKSTSLIDSLGLKPNQRATNSIAKFRRQNSCTIEFDLGGNEHEKGESINEAEDDKGNETVTLDLGRSLFRSDSVTDTRLKLSALVKALEESIPRQTVTMRLIAESLMDCVSKKKDSWIIIEGRDTTAKRRVARTVSESVFGSFESLVHIDLKKKGNESKASPATLLAYELKNPEKVVFLIEDIDLADSRFLKLLADRFEDKRRIKTGIDHRQAIFILTKEDSRNVRNRDSVLQIGLEITAQSPGKKRKPESDLSIENGFWMKKEVCSRQSSFNSSYLDLNIKAEDEEVEGEISPISSDLTGEEETEFSSSSNFLNRIQNRFVLNRSCEPGIEKGMITAAFREIFPEREEGGGVRFSVEDKLVEELYGIQNGAFERWLKEVFQTGLLTVKKGGKKDTGVIRMVFGGIVDNKGYGGGVGGYMATFLPNKVQVSKFE
What is the function of this protein?
May function in a transcriptional corepressor complex.
What are the official names of this protein?
Protein SMAX1-LIKE 5, AtSMXL5.
What is the protein family that this protein belongs to?
Belongs to the ClpA/ClpB family.
Protein: UBX2B_MOUSE
Sequence: MAEGGRAEPEEQERGSSRPRPPSARDLQLALAELYEDEMKCKSSKPDRSTPATCRSPRTPPHRLYSGDHKYDGLHIVQPPTGKIVNELFKEAREHGAVPLNEATRSSREDKTKSFTGGGYRLGNSFYKRSEYIYGENQLQDVQVLLKLWRNGFSLDDGELRPYSDPTNAQFLESVKRGETPLELQRLVHGAQVNLDMEDHQDQEYIKPRLRFKAFSGEGQKLGSLTPEIVSTPSSPEEEDKSILNAAVLIDDSMPTTKIQIRLADGSRLVQRFNSTHRILDVRDFIVRSRPEFATTDFILVTSFPSKELTDETVTLQEADILNTVILQQLK
What is the function of this protein?
Adapter protein required for Golgi and endoplasmic reticulum biogenesis.  Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis.  The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L.  VCPIP1 is also required, but not its deubiquitinating activity.  Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase.  Also, regulates spindle orientation during mitosis.
What are the official names of this protein?
UBX domain-containing protein 2B, NSFL1 cofactor p37, p97 cofactor p37.
What is the protein family that this protein belongs to?
Belongs to the NSFL1C family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol. Endoplasmic reticulum. Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes to centrosome during mitotic prophase and metaphase.
Protein: RL7_DESAH
Sequence: MADVTKDDVVEFIANMSVLELSELVKELEEKFGVSAAAPVAMMAAGGAADAGAAAEEQTEFDVILEAAGDKKIGVIKEVRAITGLGLKEAKALVDEAPKPVKEGIVKEEAEKIKAQLEAAGAQVSVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: DPOL_THES9
Sequence: MILDTDYITENGKPVIRVFKKENGEFKIEYDRTFEPYFYALLKDDSAIEDVKKVTAKRHGTVVKVKRAEKVQKKFLGRPIEVWKLYFNHPQDVPAIRDRIRAHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELTMLAFDIETLYHEGEEFGTGPILMISYADGSEARVITWKKIDLPYVDVVSTEKEMIKRFLRVVREKDPDVLITYNGDNFDFAYLKKRCEELGIKFTLGRDGSEPKIQRMGDRFAVEVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGKPKEKVYAEEIAQAWESGEGLERVARYSMEDAKVTYELGREFFPMEAQLSRLIGQSLWDVSRSSTGNLVEWFLLRKAYKRNELAPNKPDERELARRRGGYAGGYVKEPERGLWDNIVYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPEVGHKFCKDFPGFIPSLLGDLLEERQKIKRKMKATVDPLEKKLLDYRQRAIKILANSFYGYYGYAKARWYCKECAESVTAWGREYIEMVIRELEEKFGFKVLYADTDGLHATIPGADAETVKKKAKEFLKYINPKLPGLLELEYEGFYVRGFFVTKKKYAVIDEEGKITTRGLEIVRRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKLSKYEVPPEKLVIHEQITRDLRDYKATGPHVAVAKRLAARGVKIRPGTVISYIVLKGSGRIGDRAIPADEFDPTKHRYDAEYYIENQVLPAVERILKAFGYRKEDLRYQKTKQVGLGAWLKVKGKK
What are the official names of this protein?
DNA polymerase.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.
Protein: PLSY_ALBFT
Sequence: MRQQENFLESMQSFFPLAATLLGYLIGSLSFAVIVSRVMGLNDPRTFGSKNPGATNVLRSGSKTAAIVTLLLDAAKGWLPVMLVRWYGKPYGMEEGTMALVGLAAFIGHLYPVFFNFAGGKGVATALGVLLGLSPILALATGATWLIMAYFFRYVSLASLTAAVFVPVYYVFGDGMAWYLSKGVLAALCAMSLLLIYRHAENISRLIKGTESRLGKKARTERKS
What is the function of this protein?
Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA).  This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
What are the official names of this protein?
Glycerol-3-phosphate acyltransferase, Acyl-PO4 G3P acyltransferase, Acyl-phosphate--glycerol-3-phosphate acyltransferase, G3P acyltransferase, GPAT, Lysophosphatidic acid synthase, LPA synthase.
What is the protein family that this protein belongs to?
Belongs to the PlsY family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RS10_CHLTB
Sequence: MKQQKQRIRIRLKGFDQGQLDQSTANIVETAKRTGARVVGPIPLPTKREVYTVLRSPHVDKKSREQFEIRTHKRLIDILDPTGKTIDALKMLSLPAGVDIKIKAA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RF3_METCA
Sequence: MSELEFEIERRRTFAIISHPDAGKTTLTEKLLLFGGAIQLAGSVKGRKATRHATSDWMEMEKQRGISVTTSVMQFQHRDRIFNLLDTPGHEDFSEDTYRTLTAVDSALMVIDSAKGVEERTIKLMEVCRLRDTPILTFINKLDREGREPVELLDEVERVLNIQCAPITWPIGMGKRFKGVYHLYEDAIHLFSASHGDRIVKGEVVEGLNSPKLDELLGDIADELRMEIELVRGASHEFDPDAYRAGRQTPVFFGSAINNFGILELLDAFAEYAPPPQARQARERLVAPGEDKFSGFVFKIQANMDPAHRDRIAFLRVCSGRYTKGVRLFHVRSGKAMQVANAITFQADSRENVEEAYPGDIIGLHNHGTIQVGDTFTQGENLKFEGIPSFAPELFRRVVLKDPLRSKALQRGLQQLSEEGATQLFKPLRNNDLILGAVGVLQFDVTAFRLKAEYNVDCVYEAVPVTTARWVSCSDPKKLEEFKRKVHDNLAEDGSGYLVYLATSRVNLSLTEERWPEIRFSATREL
What is the function of this protein?
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2.  It binds guanine nucleotides and has strong preference for UGA stop codons.  It may interact directly with the ribosome.  The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.
What are the official names of this protein?
Peptide chain release factor 3, RF-3.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPG_HYDS0
Sequence: MIKRRKTREITLGTLKIGGNNPIVVQSMTSTKTHDIEATISQIDRLIKAGCEAIRVAVPAKEDAEALKEIVKYSEVPIIADIHFVPYMAFLSMEAGAHGIRINPGNINKKEIVRDIVLEAKKRNICVRLGVNSGSLEKHLLEKYGYPSAEALAESALNWSEFFESLGFYNFKVSIKGSDVIQNALANEIFAEKTDTPLHIGITEAGMGTQGIVKSSVGLGILLYKGIGDTIRVSLTDEPEKEVEVAYEILKSLGLKKKGIDIVSCPTCGRIEVNLPNVVKQVQEALKDKDLSIKVAIMGCAVNAIGEASHADVGLACMKGGALLFKNGKILKKVTEENMVSELLETIEKYYQEV
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: GSC_SAGLB
Sequence: MPASMFSIDNILAARPRCKDSVLPVAPSAAAPVVFPALHGDSLYGASGGASSDYGAFYPRPVAPGGAGLQAAVGGSRLGYNNYFYGQLHVQAAPVGPACCGAVPPLGAQQCSCVPTPPGYEGPGSVLVSPVPHQMLPYMNVGTLSRTELQLLNQLHCRRKRRHRTIFTDEQLEALENLFQETKYPDVGTREQLARKVHLREEKVEVWFKNRRAKWRRQKRSSSEESENAEKWNKTSSSKASPEKREEEGKSDLDSDS
What is the function of this protein?
Regulates chordin (CHRD).  May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis.  In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity).  Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals (By similarity).
What are the official names of this protein?
Homeobox protein goosecoid.
What is the protein family that this protein belongs to?
Belongs to the paired homeobox family. Bicoid subfamily.
What are the subcellular locations of this protein?
Nucleus.