PharMolix/UniProtQA huggingface dataset:
Protein: MIAA_STRP8
Sequence: MTKIKIVVIVGPTAVGKTALGISLAKAFNGEIISGDSQQVYRQLDIGTAKATQEEQEAAVHHLIDIREVTESYSAYDFVQDAQKAISDIVSRGKLPIIVGGTGLYLQSLLEGYHLGGQVDQEAVKAYRNELEQLDDHDLYERLQVNNITIEQVNRRRAIRALELAQFADELENAETAYEPLIIGLNDDRQVIYDRINQRVDRMLENGLLEEAKWLYEHYPTVQASRGIGYKELFPYFVGEMTLAEASDQLKQNTRRFAKRQLTWFRNRMAVSFTAITAPDYPQVVHDRVRDFLGQKEKS
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: ATPE_PANGI
Sequence: MTLNLCVLTPNRTVWDSKVNEIILSTNNGQIGVLPDHASIATAVDIGILRIRLNDQWLTMALMGGFARIGNNEITVLVNDAEKSSDIDSQEAQQTLEIAEANLRKAEGKRQKIEANLALRRARTRVETINAISELVGVPE
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, chloroplastic, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein.
Protein: RN222_MOUSE
Sequence: MSEGGSKDSSGSECPVCYEKFRDLDGASRTLSCGHVFCHDCLVKYLLSTRVDGQVQRTIVCPICRYVTFLSKKSSRWPSMLDKSSQTLTVPVGLPSTPSPDRGGHTNPLVISHQVWRQSSSQGSQVPLDLLPSLPRESQIFIISRHGMPLGEQDSVLPRRSLAEISEASPAPSATRSFCCRSRALLLITLIAVVAVVAAILPWVLLVRKQA
What are the official names of this protein?
RING finger protein 222.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: GLNE_BORPE
Sequence: MSSAPPFAAALAWSGHLRRRLDAHPDLAAWLANACAHPVSANVLAAWQAELSGPDAPEVLPVEQCRGMLRKLRERVFLTLIVRDLGGQADLEEVVGAMTVLADIAVGTAYRSVAAELAAVHGLPREQSTGDPQEMLIVGMGKLGGRELNVSSDIDLVMLYGDEGETDGPRRISNHEFYGRLTRRMMPVLSEVDADGQVFRTDLRLRPDGDAGPLAWSLDALEHYLIGQGREWERYAWLKARLMPAQAFADSNPDAQARQLESLRVPFVYRKYFDFDALAALRALRERIRQDWQRRALARNGVDSANNIKLGDGGIREIEFIVQLSQLIRGGRMPALQRRGLLEALHAERAAGLVPEGDAQKLEAAYRFLRRTEHALQYREDEQTHLLPADPAQRAALAAALGYEPAAFERTLAEHRAFVSQTFRNAFRLAGMGEEDDSPAPARTHANGHAMRPHAGALHDIEERLAGQIQRDFPEHAEDLLRRTETLLGSHRVRSLPDSSRHRLEALLPAALTAATQTSAPMDAALRLFDLIETIAQRSAYLALLAEYPDTLARVARMVAASPWAAQYLTQHPLLLDSLIDWRTLFEPLDFAQVAHQLAADLDACRLPDGEPDIERQMNLMRDVQRQASFQLLAQDLEGELTVEKLADQLSALADLLLAETIRRVWPLVNRRPGAEPHLAVIAYGKLGGKELGYASDLDLVFLFDDDREDAAELYAKLGRRMTSWLSTMTSSGRLYEVDLRLRPDGNAGLLAVSLEAFEQYQRSHAWPWEHQALTRARYAAGDTEAGARFERIRADILVMPRDVQALRGEVLGMRDKISAGHPNRSELFDVKHDRGGMVGVEFVTQYLVLCHAATHRVLVNNLGNIALLRLAGEAGLIPAPLALAAGDAYRTLRRAQHQLRLKGVDKARVPPGQLAAERATVCELWQTVLQDGTIAQAEVK
What is the function of this protein?
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia.  When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity.  Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity.  The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.
What are the official names of this protein?
Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme, ATP:glutamine synthetase adenylyltransferase, ATase.
What is the protein family that this protein belongs to?
Belongs to the GlnE family.
Protein: UBIM_PONAB
Sequence: MQLFVRAQKLHTLEVTGQETVAQIKAHVASLEGIAPEDQVVLLAGAPLEDEATLGQCGVEALTTLEVAGRMLGG
What are the official names of this protein?
Ubiquitin-like protein FUBI.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
Protein: YH82_CAEEL
Sequence: MFVGPHRCFLISLIVYTLTVTTSSARLILEDTTVRSEEDSGPSCPVLADEPVGEVMERICDMCHELSSHSRPNMRVECRADCFTTDAFRECLKLFTPRRHTRHLRQKY
What are the official names of this protein?
Uncharacterized protein ZC168.2.
What is the protein family that this protein belongs to?
Belongs to the arthropod CHH/MIH/GIH/VIH hormone family.
Protein: YME3_ACIFR
Sequence: MTTKRKVEVFSAGCPSCQTAIELVNRLACGSCEVSILDMNDINVAKRARDLGVRSVPAVAINGQLASCCSGSGIEEQALRWPRQA
What are the official names of this protein?
Uncharacterized 9.0 kDa protein in mobE 3'region, ORF 8.
Protein: Y1116_STAS1
Sequence: MDKKDYKKFYLIREDVLPESVVKTLKIKEVLKNDPSLSIFEAVKQFDLSRSAFYKYRDTIFPIDEKIESTREFTLILYVNDIVGMLAEVLNTLSNLDLSILTIHQSIPMEGRATITLSLDATSTDLEIDDVMEALRIVDHVSKVELISMTI
What are the official names of this protein?
UPF0735 ACT domain-containing protein SSP1116.
What is the protein family that this protein belongs to?
Belongs to the UPF0735 family.
Protein: PTPB_STAAW
Sequence: MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVSNYVEDLVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAHFGLQNHVFTLHEYVKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC
What is the function of this protein?
Dephosphorylates the phosphotyrosine-containing proteins.
What are the official names of this protein?
Low molecular weight protein-tyrosine-phosphatase PtpB, Phosphotyrosine phosphatase B, PTPase B.
What is the protein family that this protein belongs to?
Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
Protein: Y2789_STAA8
Sequence: MIHSKRLRLWLYLVLLAVFIGACGMKKEESSKDKQIKENFNKTLSLYPTKNLEDFYDKEGFRDQEFEKGDKGTWIIHSKMTIETNGKNMESRGLVLYVDRNTRTTKGEFIVRELWEDKKGYSRSKEKEYPVKMEHNKIIPTKPIADDKLRKEIENFKFFVQYGDFKDINDYKDGDISYNPNVPSYSAKYQLSNDDYNVKQLRKRYDIPTKKAPKLLIKGDGDLKGSSIGHKNLEFTFIENKEENIYFTDSINFKPTE
What are the official names of this protein?
Uncharacterized lipoprotein SAOUHSC_02789.
What is the protein family that this protein belongs to?
Belongs to the staphylococcal tandem lipoprotein family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: US11_HCMVM
Sequence: MNLVMLILALWAPVAGSMPELSLTLFDEPPPLVETEPLPPLPDVSEYRVEYSEARCVLRSGGRLEALWTLRGNLSVPTPTPRVYYQTLEGYADRVPTPVEDISESLVAKRYWLRDYRVPQRTKLVLFYFSPCHQCQTYYVECEPRCLVPWVPLWSSLEDIERLLFEDRRLMAYYALTIKSAQYTLMMVAVIQVFWGLYVKGWLHRHFPWMFSDQW
What is the function of this protein?
Participates in the inhibition of the host immune response.  Redirects newly synthesized major histocompatibility complex (MHC) class I heavy chains via the SEC61 translocon to the cytosol where they undergo proteasome-dependent destruction.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
What are the official names of this protein?
Membrane glycoprotein US11.
What is the protein family that this protein belongs to?
Belongs to the cytomegalovirus US6 family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Single-pass type I membrane protein.
Protein: AMPP3_LEPMJ
Sequence: MTRTMVVTVRFCTFLINVDDEWDANPWLPEQVSLDPRPPLKHRPKLNFDMSAFSSRGMRLARTLQRRYTRRPLPTYQQPTPFTFRILPAEDREWCSISTMAIAENYEDVLKGKYPAKEHARKVAKWIIEKGGDKNGTIYLEAQKQKLNEDNDGEAPFRQRRYFFYLSGCELPDSYLTYEIPNDRLTLFIPPVEPEEVIWSGLPMSVDEAKAKYDIDDCKTTRDINAHLTSTSESAQSTIYAIPEQVSDNITFLSYKDKEFKQLKPAIEYCRVTKTDYEIALIRKANEISTAAHIAVMKAASKAKNECELEAVFLKSCVERNAKNQAYHSIVAAGENGATLHYVNNAAPISEQNLLLLDAGCEVDCYASDITRTFPIKGHFNEESLAIYKIVLDMQHQCINALKAGVLWDSIHELAHKIAIKGLLDLGILKGDADAIFKARASVAFFPHGLGHYLGMDTHDTGGNANYADKDVMFRYLRVRGTLPERSVITVEPGIYFCRFIIEPYLKDEEKKQFFDEKVLEKYWSVGGVRIEDNILITKEGIENLTPTPKEVDEITALVQSA
What is the function of this protein?
Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides.
What are the official names of this protein?
Probable Xaa-Pro aminopeptidase PEPP, Aminoacylproline aminopeptidase, Prolidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M24B family.
Protein: EDNRA_SHEEP
Sequence: METFWLRVSFWVALVGGVISDNPESYSTNLSIHVDSVTTFRGTELSFVVTTHQPTNLALPSNGSMHNYCPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFEQNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYKGAQHRTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDTNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCYQSKSLMTSVPMNGTSIQWKNPEQNNHNTERSSHKDSIN
What is the function of this protein?
Receptor for endothelin-1.  Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.  The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity).
What are the official names of this protein?
Endothelin-1 receptor, Endothelin receptor type A, ET-A, ET-AR.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MANI_THEFU
Sequence: MTLWTARAAHRAWLDAEARRLVDFAAAADHPEHGFAWLDGSGAPLPEQGVHTWITCRVTHVAALAHLEGIPGASALADHGLRALAGPLRDPEHDGWFTALDSRGTVADSRKEAYQHAFVLLAAASATVAGRPGARELLDAAAAVIEQRFWEEETGRCRESWDAAWHADEPYRGANSNMHLVEAFLAAFDATGDRVWAERALRIAHFFVHEVAAPRDWRLPEHFTPDWQVVADYNTDDRAHPFRPYGVTVGHVLEWARLLVHVEAALPDPPSWLLADAEAMFAAAVARGWSVDGTEGFVYTLDYDDTPVVRSRMHWVVAEAISAAAVLGQRTGDERYEHWYRTWWDHAATYFVDTVQGSWHHELDPTLAPPPGGTWSGKPDVYHAYQATRLPLLPLAPSLAGALATVG
What is the function of this protein?
Catalyzes the reversible isomerization of D-mannose to D-fructose.  Shows weaker activity on D-lyxose, but cannot use N-acetyl D-glucosamine.
What are the official names of this protein?
D-mannose isomerase.
What is the protein family that this protein belongs to?
Belongs to the N-acylglucosamine 2-epimerase family.
Protein: DLDH_RAT
Sequence: MQSWSRVYCSLAKKGHFNRLSHGLQGASSVPLRTYSDQPIDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYHLAHGKDFASRGIEIPEVRLNLEKMMEQKRSAVKALTGGIAHLFKQNKVVHVNGFGKITGKNQVTATTADGSTQVIGTKNILIATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKLVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGIGIDMEISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSVEAASGGKAEVITCDVLLVCIGRRPFTQNLGLEELGIELDPKGRIPVNTRFQTKIPNIFAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGKSEEQLKEEGVEFKVGKFPFAANSRAKTNADTDGMVKILGHKSTDRILGAHILGPGAGEMVNEAALALEYGASCEDVARVCHAHPTLSEAFREANLAASFGKPINF
What is the function of this protein?
Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex).  The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion.  A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.  In monomeric form may have additional moonlighting function as serine protease (By similarity).  Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction (By similarity).
What are the official names of this protein?
Dihydrolipoyl dehydrogenase, mitochondrial, Dihydrolipoamide dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Nucleus. Cell projection, cilium, flagellum. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly localizes in the mitochondrion. A small fraction localizes to the nucleus, where the 2- oxoglutarate dehydrogenase complex is required for histone succinylation.
Protein: UBIC_SALDC
Sequence: MSHPALTRLRALRYFDAIPALEPHLLDWLLLEDSMTKRFEQQGKRVSVTLIREAFVGQSEVEEASGLLPSESRYWLREILLCADGEPWLAGRTVVPESTLCGPEQVLQHLGKTPLGRYLFTSSTLTRDFIEIGRDATLWGRRSRLRLSGKPLLLTELFLPASPLY
What is the function of this protein?
Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.
What are the official names of this protein?
Chorismate pyruvate-lyase, CL, CPL.
What is the protein family that this protein belongs to?
Belongs to the UbiC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHLH_ORYSJ
Sequence: MSSLVSTPFTTATGVQKKLGAPVPLHSFLLSRRQPAAGAGRGRAAAAAIRCAVAGNGLFTQTKPEVRRVVPPEGDASRRGVPRVKVVYVVLEAQYQSSVTAAVRELNADPRRAAGFEVVGYLVEELRDEETYKTFCADLADANVFIGSLIFVEELALKVKDAVEKERDRMDAVLVFPSMPEVMRLNKLGSFSMSQLGQSKSPFFQLFKRKKNSGGFADSMLKLVRTLPKVLKYLPSDKAQDARLYILSLQFWLGGSPDNLQNFLKMIAVSYVPALKGADIKYDDPVLFLDAGIWHPLAPTMYDDVKEYLNWYGTRRDTNDKLKDPNAPVIGLVLQRSHIVTGDDGHYVAVIMELEAKGAKVIPIFAGGLDFSGPTQRYLVDPITGKPFVNAVVSLTGFALVGGPARQDHPKAIAALQKLDVPYIVALPLVFQTTEEWLNSTLGLHPIQVALQVALPELDGGMEPIVFAGRDPRTGKSHALHKRVEQLCTRAIRWAELKRKTKEEKKLAITVFSFPPDKGNVGTAAYLNVFNSIYSVLQDLKKDGYNVEGLPDTAEALIEEVIHDKEAQFNSPNLNVAYRMNVREYQSLTSYASLLEENWGKPPGNLNSDGENLLVYGKQYGNVFIGVQPTFGYEGDPMRLLFSKSASPHHGFAAYYTFVEKIFQADAVLHFGTHGSLEFMPGKQVGMSDACYPDSLIGNIPNIYYYAANNPSEATVAKRRSYANTISYLTPPAENAGLYKGLKQLSELISSYQSLKDTGRGPQIVSSIISTAKQCNLDKDVPLPEEGVELPPNERDLIVGKVYAKIMEIESRLLPCGLHVIGEPPSAIEAVATLVNIASLDRPEDEIYSLPNILAQTVGRNIEDVYRGSDKGILADVELLRQITEASRGAITTFVERTTNNKGQVVDVTNKLSTMLGFGLSEPWVQHLSKTKFIRADREKLRTLFTFLGECLKLIVADNELGSLKLALEGSYVEPGPGGDPIRNPKVLPTGKNIHALDPQAIPTTAALKSAKIIVDRLLERQKVDNGGKYPETIALVLWGTDNIKTYGESLAQVLWMIGVRPVADTFGRVNRVEPVSLEELGRPRIDVVINCSGVFRDLFINQMNLLDRAVKMVAELDEPEEMNYVRKHAQEQARELGVSLREAATRVFSNASGSYSSNVNLAVENASWTDEKQLQDMYLSRKSFAFDCDAPGAGMREQRKTFELALATADATFQNLDSSEISLTDVSHYFDSDPTKLVQGLRKDGRAPSSYIADTTTANAQVRTLSETVRLDARTKLLNPKWYEGMMKSGYEGVREIEKRLTNTVGWSATSGQVDNWVYEEANATFIEDEAMRKRLMDTNPNSFRKLVQTFLEASGRGYWETSEENLEKLRELYSEVEDKIEGIDR
What is the function of this protein?
Involved in chlorophyll biosynthesis.  Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX.  The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step.  May be involved in the plastid-to-nucleus retrograde signaling.
What are the official names of this protein?
Magnesium-chelatase subunit ChlH, chloroplastic, Mg-chelatase subunit H, Mg-protoporphyrin IX chelatase subunit ChlH.
What is the protein family that this protein belongs to?
Belongs to the Mg-chelatase subunit H family.
What are the subcellular locations of this protein?
Plastid, chloroplast stroma. Plastid, chloroplast membrane; Peripheral membrane protein; Stromal side. Plastid, chloroplast membrane; Peripheral membrane protein; Cytoplasmic side. Note=Predominantly associated with the chloroplast envelope. Spans the chloroplast envelope and its N- and C- termini are exposed to the cytosol (By similarity).
Protein: FTSP_SHIDS
Sequence: MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRRGQPLFMTVQRAHWSFTLGTRASVWGINGSYLGPTIRVWKGDDVKLIYSNRLTENVSMTVAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGMWLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQSPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPGERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTDSLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADEPQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNSQTLEMADRGSIGQLLVNPVP
What is the function of this protein?
Cell division protein that is required for growth during stress conditions.  May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
What are the official names of this protein?
Cell division protein FtsP.
What is the protein family that this protein belongs to?
Belongs to the FtsP family.
What are the subcellular locations of this protein?
Periplasm. Note=Localizes to the division septum.
Protein: NUOI_CHESB
Sequence: MSALAQAAKSLLLKEFFGAVVLSMRQFFAPKATLNYPHEKGPLSPRFRGEHALRRYPNGEERCIACKLCEAICPAQAITIEAGPRRNDGTRRTVRYDIDMVKCIYCGFCQEACPVDAIVEGPNFEFATETREELYYDKDKLLANGDRWERELARNIALDAPYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PHS_SHEB5
Sequence: MTALSNMKCEACQADAPKVTDEELAELIRMIPDWGVQVRDGVMQLERIYKFKNFKLAMAFTNKLADLAEEEFHHPGIFTEWGKVTVTWWSHSIKGLHKNDFIMAAKTDQLLV
What are the official names of this protein?
Putative pterin-4-alpha-carbinolamine dehydratase, PHS, 4-alpha-hydroxy-tetrahydropterin dehydratase, Pterin carbinolamine dehydratase, PCD.
What is the protein family that this protein belongs to?
Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
Protein: FABH1_STRCO
Sequence: MSKIKPSKGAPYARILGVGGYRPTRVVPNEVILEKIDSSDEWIRSRSGIETRHWAGPEETVAAMSVEASGKALADAGIDASRIGAVVVSTVSHFSQTPAIATEIADRLGTDKAAAFDISAGCAGFGYGLTLAKGMVVEGSAEYVLVIGVERLSDLTDLEDRATAFLFGDGAGAVVVGPSQEPAIGPTVWGSEGDKAETIKQTVSWDRFRIGDVSELPLDSEGNVKFPAITQEGQAVFRWAVFEMAKVAQQALDAAGISPDDLDVFIPHQANVRIIDSMVKTLKLPEHVTVARDIRTTGNTSAASIPLAMERLLATGDARSGDTALVIGFGAGLVYAATVVTLP
What is the function of this protein?
Essential enzyme that catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III 1, Beta-ketoacyl-ACP synthase III 1, KAS III 1, 3-oxoacyl-[acyl-carrier-protein] synthase 3 1, 3-oxoacyl-[acyl-carrier-protein] synthase III 1.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL5_ECOSE
Sequence: MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: DTD_BACC1
Sequence: MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAERLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_LEPIN
Sequence: MEVKSAKELKRISKELQENFLNRWKLLNLEQDKDRLKSLTEKAEDPNLWNNPEEARLVSQKKNELEKKLNPWFTIQQDILDFPDLVDLTLDEKGENGVGELSSEYNRLQEKFEELELLGALKNPEDLKPAFLNIHPGAGGTESQDWAEMLLRMYTRYFEKKGYQYSLIDVQAGDGAGIKNATLHVIGDFAFGFLKGENGVHRLVRISPFDANKRRHTSFVSVHVSPEIDDDIDIKIEEKDIRVDVYRSSGAGGQHVNTTDSAVRITHMPSGIVVACQNERSQIKNRDTAFKMLKARLYELEQEKAKEELEKKSGEKKDIAWGSQIRSYVFHPYNLVKDHRTDHETGNVAAVMDGDIEPFILAYLKTL
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL1_AZOC5
Sequence: MAHQGKRVRAANEGIDRLKLYPLDEALALLKARTTAKFDETIEVAINLGVDPRHADQMVRGVCNLPNGSGRTVRVAVFARGAKADEAKAAGADIVGAEDLLETIQGGTIEFDRCIATPDLMPLVGRLGKVLGPRGLMPNPKVGTVTMDVKGAVAAAKGGAVEFRVEKAGIIHGGIGKASFPADKLAENIRAFVDAVVKAKPTGAKGTYVQRVAVSSTMGPGIKVDTASVVTA
What is the function of this protein?
Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.
What are the official names of this protein?
50S ribosomal protein L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL1 family.
Protein: PDXH_PSEMY
Sequence: MTQTLADMRRDYTRDGLSEAQAPLDPFTLFRQWFDDAVKTEQLPVEPNAMTLATVDEDGRPHCRVLLLKGLDERGFTFFSNYESAKGRQLAARPYAAMTFFWPSLERQVRIEGRVERVTPAESDGYFQVRPLGSRIGAWASPQSRVIRDRAELENLLAETEKRFLNQAPHCPPHWGGYRLLPERIEFWQGRPSRLHDRLDYRLQGEAWIRQRLAP
What is the function of this protein?
Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
What are the official names of this protein?
Pyridoxine/pyridoxamine 5'-phosphate oxidase, PNP/PMP oxidase, PNPOx, Pyridoxal 5'-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxamine 5'-phosphate oxidase family.
Protein: FADD_HUMAN
Sequence: MDPFLVLLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLRELLASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTKIDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNLVADLVQEVQQARDLQNRSGAMSPMSWNSDASTSEAS
What is the function of this protein?
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors (PubMed:7538907, PubMed:23955153, PubMed:19118384, PubMed:20935634, PubMed:16762833, PubMed:24025841).  The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation (PubMed:7538907, PubMed:19118384, PubMed:20935634, PubMed:16762833).  Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (PubMed:16762833).  Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (PubMed:21109225).
What are the official names of this protein?
FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity.