PharMolix/UniProtQA huggingface dataset:
Protein: PSTB_CHRVO
Sequence: MTTMTSTASKLEVRDLNFFYGNFHALKGIQLEIAPRKVTAFIGPSGCGKSTLLRTFNRMYELYPGLRAEGEIMLDGQNILGRDIDVNLLRAKVGMVFQKPTPFPMSIYDNITFGVKLYEKLSKGEMEDRVEWALRKAALWDEVKDKLKQSGNSLSGGQQQRLCIARAVASKPEVLLLDEPTSALDPISTAHIEELIHELKEDYTIAIVTHNMQQAARVSDYTAYMYLGELVEFGNTDTIFTTPQKKATEDYITGKFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PNO1_KLULA
Sequence: MVAPTALKKSDVSEGTVPVTTTSRIVGVDNTEKIDEDDDDADVLIDQDGDAMLVDEENNEESNKKKEDAGVVLDAEGKPRFTSAASSAQTKVKLESRKVSVPPHRMTPLKNNWSKIYPPLVDHLKLQVRMNLKTKSVELRTHPKHTTDPGALQKGADFIKAFTLGFDLDDSIALLRLDDLYIETFEIKDVKTLQGDHLSRAIGRIAGKDGKTKFAIENATRTRIVLADSKIHILGGFTHIRMARESVVSLILGSPPGKVYGNLRTVASRLKERY
What is the function of this protein?
Required for small ribosomal subunit (SSU) synthesis.  Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species (By similarity).
What are the official names of this protein?
Pre-rRNA-processing protein PNO1.
What is the protein family that this protein belongs to?
Belongs to the PNO1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus.
Protein: TBA_ZYMTR
Sequence: MREVISLNVGQAGCQIANSCWELYCLEHGIQPDGYLTEERKAAEDDDGFSTFFSETGNGKYVPRTIYADLEPNVVDEVRTGTYRSLFHPELMITGKEDASNNYARGHYTVGKELIDQVLDKVRHVADNCSGLQGFLVFHSFGGGTGSGFGALLMERLSVDYGKKCKLEFCVYPAPQVATSVVEPYNSILTTHTTLEHSDCSFMVDNEAIYDICRRNLGIERPNYENLNRLIAQVVSSITASLRFDGSLNVDLNEFQTNLVPYPRIHFPLVAYAPIVSAAKAAHEANSVQEISMSCFEPNSQMVKCDPRNGKYMATCLLYRGDVVPKDVHQAVATLKTKRTIQFVDWCPTGFKIGICYQPPQNVPNGDLAKVNRAVCMLSNTTAIAEAWSALSHKFDLMYSKRAFVHWYVGEGMEEGEFSEAREDLAALERDYEEVAADSAEGDEGGEAEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DIRA2_MACFA
Sequence: MPEQSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQFPAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDMESIPIMLVGNKCDESPSREVQSSEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVIM
What is the function of this protein?
Displays low GTPase activity and exists predominantly in the GTP-bound form.
What are the official names of this protein?
GTP-binding protein Di-Ras2, Distinct subgroup of the Ras family member 2.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Di-Ras family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: CSL4_SCHPO
Sequence: MNLVLPGQVVARGAPNGEGTVKRGDYIISTRTGIFDPEKNSVTYPRKVEETAVLPNVGSIVLARVSRINARQATVNISVVDDVCTKDEFQGVIHVQDIRATEKNKVKVQNSFRPGDIVRALVISLGDGSSYFLTTARNDLGVIFAQSSETGEQMFPVDYQHMQTKSGYTEMRKCAKPILDE
What is the function of this protein?
Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.  In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and cryptic unstable transcripts (CUTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm.  In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and in RNA surveillance pathways, preventing translation of aberrant mRNAs.  The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes (By similarity).
What are the official names of this protein?
Exosome complex component csl4.
What is the protein family that this protein belongs to?
Belongs to the CSL4 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Cytoplasm.
Protein: LPXM2_SHIFL
Sequence: MKKYKSEFIPEFKKNYLSPVYWFTWFVLGMIAGISMFPPSFRDPVLAKIGRWVGRLSRKARRRATINLSLCFPEKSDTEREIIVDNMFATALQSIVMMAELAIRGPEKFQKRVFWKGLEILEEIRHNNRNVIFLVPHGWSVDIPAMLLAAQGEKMAAMFHQQRNPVIDYVWNSVRRKFGGRLHSREDGIKPFIQSVRQGYWGYYLPDQDHGPEYSEFADFFATYKATLPIIGRLMNISQAMIIPLFPVYDEKKHFLTIEVRPPMDACIASADNKMIARQMNKTVEILVGSHPEQYIWVLKLLKTRKSNEADPYP
What is the function of this protein?
Catalyzes the transfer of an acyl chain from an acyl-[acyl-carrier-protein] (ACP) to a Kdo(2)-(acyl)-lipid IV(A) to form a Kdo(2)-lipid A.
What are the official names of this protein?
Lipid A biosynthesis acyltransferase 2, Kdo(2)-lauroyl-lipid IV(A) acyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: HIS4_STAEQ
Sequence: MIDLWPAIDLINSTSVRLTEGKYDSKEKMEKSVEDSIRFYSQFKCVKRIHIVDLIGAKAKEVKEFDYIRSLRKLTTKPIEVGGGIRSKQTIENYIHSGIDYCIVGTKGIQDIEWLTHMTHQFPNKLYLSVDAFGEKIKINGWKEDAKLNLFDYVAKIEHLPLGGVIYTDISKDGKLSGPNFDLTGRLALYTSLPVIASGGIRHQEDLFRLESLNVHAAIVGKAAHLDEFWEGLS
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACO11_MOUSE
Sequence: MIQNVGNHLRRGFASMFSNRTSRKSISHPESGDPPTMAEGEGYRNPTEVQMSQLVLPCHTNHRGELSIGQLLKWIDTTACLSAERHAGCPCVTASMDDIYFDHTISVGQVVNIKAKVNRAFNSSMEVGIQVVSEDLCSEKQWSVCKALATFVAHRELSKVKLKQVIPLTEEEKTEHGVAAERRRMRLVYADTIKDLLTHCVIQDDLDKDCSNMVPAEKTRVESVELVLPPHANHQGNTFGGQIMAWMENVATIAASRLCHAHPTLKAIEMFHFRGPSQVGDRLVLKAIVNNAFKHSMEVGVCVEAYRQEAETQRRHINSAFMTFVVLDKDDQPQKLPWIRPQPGEGERRYREASARKKIRLDRKYLVSCKQAEVALSVPWDPSNQVYLSYYNVSSLKTLMAKDNWVLSVEISEVRLYILEEDFLSFHLEMVVNVDAAQVFQLLSDLRRRPEWDKHYRSVELVQQVDEDDAIYHVISPALSGNTKPQDFVILASRRKPCDNGDPYVIALRSVTLPTHHETPEYQRGETLCSGFCLWREGDQMTKVSYYNQATPGFLNYVTTNVSGLSSEFYNTFKACESFLLDNRNDLAPSLQTL
What is the function of this protein?
Has an acyl-CoA thioesterase activity with a preference for the long chain fatty acyl-CoA thioesters hexadecanoyl-CoA/palmitoyl-CoA and tetradecanoyl-CoA/myristoyl-CoA which are the main substrates in the mitochondrial beta-oxidation pathway.
What are the official names of this protein?
Acyl-coenzyme A thioesterase 11, Acyl-CoA thioesterase 11, Acyl-CoA thioester hydrolase 11, Adipose-associated thioesterase, Brown fat-inducible thioesterase, BFIT, Palmitoyl-coenzyme A thioesterase.
What are the subcellular locations of this protein?
Mitochondrion matrix. Cytoplasm.
Protein: LOLD1_CAUVC
Sequence: MTNVIEARGIEKVFHNGDEETRVLKGIDLTLGQGELAAMVGASGSGKSTLLSIIGLLLRPTAGTLSISGERVDDLSERMRARFRNQRLGFVFQFHHLLPDFTAMENVAFPAAAPGGGISRAMRTRARDLLARVGLEDRIDFPAARLSGGQKQRVAIARALMNRPDLIIADEPTGNLDRESADRVLDLMREVNREEGATFLICTHDDGVAARCGRRLTLSDGRLTSNVRDPGGFS
What is the function of this protein?
Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA.  Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
What are the official names of this protein?
Lipoprotein-releasing system ATP-binding protein LolD 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: IPAD_SHIDY
Sequence: MNITTLTNSISTSSFSPNNTNGSSTETVNSDIKTTTSSHPVSSLTMLNDTLHNIRTTNQALKKELSQKTLTKTSLEEIALHSSQISMDVNKSAQLLNILSKTEYPINKDARELLHSAPKEAELDGYEMISHRELWAKIANSINDINEQYLKVYEHAVSSYTQMYQEFSAVLSSLAGWISPGGNDGNSVKLQVKSLKDALTTLKKNYEDKPLYPATNTVSEQEANKWLTELGGTIGTVSAKNGGYVVSINMTPIYNMLNRLDNLGGNGEVVLDNAKYQAWNAGFSAEDETMKNNLQTLVQKYSNANSIFDNLVKVLSSTISSCTDTDKLFLHF
What is the function of this protein?
Required for bacterial invasion of host cells.  Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes.  These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm.  Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in the presence of this signal (By similarity).
What are the official names of this protein?
Invasin IpaD, 37 kDa membrane antigen.
What is the protein family that this protein belongs to?
Belongs to the invasin protein D family.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the type III secretion system (TTSS). Localizes to the tip of the external secretion needle that is part of the TTSS apparatus (By similarity).
Protein: SECB_DINSH
Sequence: MADETTNGAAAPADQQQQPVMPTLKIMAQFIRDMSFENIAAQKGVQGEGQPDIQVQVNLDAKKRTVEKQFEVAIKLNINAKTKESGDMIFGLELDYAGIFFIDNVPDEQMHPFLLIECPRMIFPFVRRIVSDVTRDGGFPPLNLDQIDFVALYRQEIARRAAAQQAAPSAEV
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLD8_HUMAN
Sequence: MATHALEIAGLFLGGVGMVGTVAVTVMPQWRVSAFIENNIVVFENFWEGLWMNCVRQANIRMQCKIYDSLLALSPDLQAARGLMCAASVMSFLAFMMAILGMKCTRCTGDNEKVKAHILLTAGIIFIITGMVVLIPVSWVANAIIRDFYNSIVNVAQKRELGEALYLGWTTALVLIVGGALFCCVFCCNEKSSSYRYSIPSHRTTQKSYHTGKKSPSVYSRSQYV
What is the function of this protein?
Tight-junction protein required for paracellular chloride transport in the kidney.  Mediates recruitment of CLDN4 to tight junction in the kidney.  Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-8.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. Note=Localizes to tight junctions in all 3 segments of the epididymis, in the caput found in the lateral margins of principal cells, and in the corpus at the interface between basal and principal cells.
Protein: RL2_FUSNN
Sequence: MAIRKMKPITNGTRHMSRLVNDELDKVRPEKSLTVPLKSAYGRDNYGHRTCRDRQKGHKRLYRIIDFKRNKLDVPARVATIEYDPNRSANIALLFYVDGEKRYILAPKGLKKGDIVSAGSKAEIKPGNALKLKDMPVGVQIHNIELQRGKGGQLVRSAGTAARLVAKEGTYCHVELPSGELRLIHGECMATVGEVGNSEHNLVNIGKAGRARHMGKRPHVRGAVMNPVDHPHGGGEGKNSVGRKSPLTPWGKPALGIKTRGRKTSDKFIVRRRNEK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: PSTB_GRABC
Sequence: MVSTVSQVSRTASHDAGGSAAAGLAAMAASRVMVESQPKIAVRNLDFYYGSHKALKSISLDVHERQVLGMIGPSGCGKSTLLRILNKMYALYPGQRAEGEVLLDGENVLGKDVDVNVLRSRVGMVFQKPTPFPMSIYENIAFGIRLHEKLSKAEMDERIEWSLTRAALWSEVKDRLHTAAAGMSGGQQQRLCIARTIAVKPEVILLDEPTSALDPISTLKIEELVDELKRDFTIAIVTHNMQQAARCADRVAFFYMGELVEVGTALDMFTNPREQRTQEYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ASTB_PSEPG
Sequence: MKSYEVNFDGLVGPTHNYGGLSYGNVASQSNSQQGSNPREAARQGLAKMKALADMGFKQGVLAPQERPDVAALRRLGFSGSDAEVIQRAAADAMPLLVASCSASSMWVANAATVSPSADTADGRVHFTAANLNCKYHRSIEHPTTSRVLGAMFNNEKHFAHHPALPAVAQFGDEGAANHTRFCSAYGEAGVEFFVYGRSAFDSRYPAPQKYPARQTLEASQAVARLHGLSDDGVVYAQQNPAVIDQGVFHNDVISVGNGEVLFYHEDAFLETDAVLGQLRAKLASKGGNFQAICVPRAAVTVEDAVRSYLFNSQLLSRDDGSMLLVVPEECRNNERVWAYLGQLTSQGGPVNEVKIFDLKQSMQNGGGPACLRLRVALKETELAAVNQGVIMTASLYDTLLQWVDRHYRDRLGEADLADPQLLVECRTALDELTQILKLGSVYPFQRQP
What is the function of this protein?
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
What are the official names of this protein?
N-succinylarginine dihydrolase.
What is the protein family that this protein belongs to?
Belongs to the succinylarginine dihydrolase family.
Protein: AOF_DANRE
Sequence: MTANAYDVIVIGGGISGLSAAKLLVDSGLNPVVLEARSRVGGRTYTVQNKETKWVDLGGAYIGPTQNRILRIAKQYGVKTYKVNEEESLVHYVKGKSYPFKGPFPPMWNPFAYMDYNNLWRTMDKMGMEIPKEAPWRAPHAEEWDKMTMQQLFDKICWTRSARRFATLFVNVNVTSEPHEVSALWFLWYVKQCGGTMRIFSTTNGGQERKFAGGANQISEGMARELGDRVKLSRAVCSIDQTGDLVEVRTVNEEVYKAKYVILAIPPGLNLKIHFNPELPPLRNQLIHRVPMGSVIKCMVYYKENFWRKKGYCGSMVIEEEDAPIGLTLDDTKPDGSVPAIMGFILARKSRKLANLTRDERKRRICEIYARVLGSEEALYPVHYEEKNWCEEEYSGGCYTAYFPPGIMTQFGRVLREPVGRLYFAGTETATEWSGYMEGAVQAGERASREVMCAMGKLHASQIWQSEPESMDVPARPFVTTFWERNLPSVGGFLKFMGVSSFLAAATAAGLVACKKGLLPRC
What is the function of this protein?
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:15621520, PubMed:16917825).  Preferentially oxidizes serotonin and tyramine (PubMed:15621520, PubMed:16917825).  Also catalyzes the oxidative deamination of kynuramine to 3-(2-aminophenyl)-3-oxopropanal that can spontaneously condense to 4-hydroxyquinoline (By similarity).
What are the official names of this protein?
Amine oxidase [flavin-containing], Monoamine oxidase, MAO, Z-MAO.
What is the protein family that this protein belongs to?
Belongs to the flavin monoamine oxidase family.
What are the subcellular locations of this protein?
Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.
Protein: CB078_MOUSE
Sequence: MSENSQSSPFFGTESTLHPSLPLLSNSIQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMGNAYLNPHAGTTMLTVLTEQGQISTSTPSYPGALKWDCTGSTHGREDALQEFNMKLIDQDTTLSSLAVTNQSDKILDPNVIVPFHPTLSSSFVQITPSQMPNQGYSLAPSYQEGSQVYYYEHNNLGPLIAGEFGQCLKAHGSVSYPGSQTSVLQPEMVMVLKEIQPRNIQMPLFTSAFSYSTSAQSMPDNGLPVVQMETSLGLPPSGQTHCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSEFLALPPAPSLEQPENKTMPEIKEGTKENQDRPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENENGSSFNFKDITRLEADIQLPQLLNTLTDIDQDQSCETWTVTSGPSDQVRKNKHKSFELLEGAPQAKFQHWDLVEGEGAGGVAGASERAIDNMAKQPEGKAPKGPPSKNRKARKQEQERPSGPQNKSKKTEELKQSRNTAKAEENLSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKTEKKTGISSFRGLRTFTINKDPGPGSGTVTTTVLNMPCEGQFPPKSPGKVQRAESSIDKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRTTTVQPHSHSAQPTTLRPAQPPPVSSSLIASAKPAPPISSSSTGPNVTNPNQSSAVPHLVTSRPVPYRASSHTSFQRELVSAARNKVPSPPKPQTKYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRQAQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM
What are the official names of this protein?
Uncharacterized protein C2orf78 homolog.
Protein: MURI_DEIRA
Sequence: MPPVSFAAASDPAPRSALPIGVFDSGAGGLSVLAELQRALPQEDVLYLADTAHVPYGARSDEDIRDLTARAVAELVRRGVKAVVVACNTASAFSLTHLRERFELPIIGLVPAVKPAVAATKSGVVGVLATPGTLRGTLLADVIRQWAEPAGVRVMQAVSTELVPLVEAGKADSPEARVVLRDVLEPLAEAGADQLVLGCTHYPFLAGSIRAEFGDTFALVDSGAAVARHTRNVLSRGGLLRGGDRTGEVSYLTTSDPAHLRALLMTLRPGGADGASLPDPPSPRIELTTT
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: JAP2_RANJA
Sequence: FGLPMLSILPKALCILLKRKC
What is the function of this protein?
Antibacterial activity against the Gram-negative bacterium E. coli and the Gram-positive bacterium S. aureus.
What are the official names of this protein?
Japonicin-2.
What are the subcellular locations of this protein?
Secreted.
Protein: ISPD_CLOPE
Sequence: MGKVVSVILAGGKGKRMGAEVSKQFIEINGKPIIYYTLKAFEECKGIDEIILVLPKDEIDYFKREIEPRFDFKISKIIEGGKERQDSVYNALNSIGDCDIVLIHDGARAFVSNKIIEDGIKYSREFGAAAPGVMPKDTIKVKNLEGFSVDTPNRASLVAVQTPQCFKYNLIKKGHNKVKNEKIQVTDDTMIVELLGEKVYLFEGDYKNIKVTTPEDLILAEHFVK
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: GLHA_HYPMO
Sequence: MFWTRYAGASILLFLMLIHLGQVYPRNDITNFGCEECKLKENNIFSKPGAPVYQCMGCCFSRAYPTPLRSKKTMLVPKNITSEATCCVAKEVKRVLVNDVKLVNHTDCHCSTCYYHKS
What is the function of this protein?
Shared alpha chain of heterodimeric glycoprotein hormones.  These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.  Involved in gametogenesis and steroidogenesis.
What are the official names of this protein?
Glycoprotein hormones alpha chain, GTH-alpha, Gonadotropin alpha chain.
What is the protein family that this protein belongs to?
Belongs to the glycoprotein hormones subunit alpha family.
What are the subcellular locations of this protein?
Secreted.
Protein: LPLA_SCHPO
Sequence: MLEAVTNPKSSLATFSKQLNGLLQAKVVVCKSVNPYFNLALENYLYENSTAKHCLLLYTNSPSVIIGRNQNPWVEANVKLCRDNFVNIIRRKSGGGTVFHDFGNLNYSVLMNREEFSHTENASIMIQALRNLGVHARLNQRHDIVLAQSQRKISGSAYKISRNRCYHHGTMLLNSDLEGVREYLRSPSTGILSKGVSSTRSPVSNTKLLKAEFIKQVISCFLLHKSHSTTTKPLSKPRASSKRLYDIEPKSVITLEQNDLLGVPSILKAVNELQSWEWTFGQTPSFKQHLESTELSVSMDISVVHGRLEKVIFSTPNATLEHELSSIPWTGLCYESGFANTFLISGIHSKEAISILKWISDSI
What is the function of this protein?
Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.
What are the official names of this protein?
Putative lipoate-protein ligase A.
What is the protein family that this protein belongs to?
Belongs to the LplA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTSE_BACSU
Sequence: MIEMKEVYKAYPNGVKALNGISVTIHPGEFVYVVGPSGAGKSTFIKMIYREEKPTKGQILINHKDLATIKEKEIPFVRRKIGVVFQDFKLLPKLTVFENVAFALEVIGEQPSVIKKRVLEVLDLVQLKHKARQFPDQLSGGEQQRVSIARSIVNNPDVVIADEPTGNLDPDTSWEVMKTLEEINNRGTTVVMATHNKEIVNTMKKRVIAIEDGIIVRDESRGEYGSYD
What is the function of this protein?
Part of the ABC transporter FtsEX involved in sporulation.  May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation.  Acts upstream of the histidine kinases KinA, KinB and KinC, the RapA phosphatase and the Spo0A sporulation protein.
What are the official names of this protein?
Cell division ATP-binding protein FtsE.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is localization dependent on FtsZ.
Protein: HIS8_XANOR
Sequence: MSTSSILHLVREDLRAFAGYSSARTSALQGDVWLNANESAWGNPADPSASTRRYPDPQPQGLRSALAALYGCAPEQLLIGRGSDEAIDLLVRGLCVPERDAVLVTPPVFGMYAVCARLQNAPLVDVPLVDVPDGFHADIPAIVAAALASNAKLVFLCSPSNPAGSAIALDQIEPALQALQGKALVVVDEAYGEFSEVPSAVGLLARYDNLAVLRTLSKAHALAAARIGTLIANAELIAVLRRCQAPYPVPTPCAAMAEQALSAPALEVTRRRIAEVRSERARVHKALVQLPGVRQVYPSQGNFLLVRFDDAEAAFQALLEAGVVVRDQRAVPRLSDALRITLGTHEQNERVLSALQRTQEAAA
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: DEOB_ANASK
Sequence: MNRRLVILVADSAGCGALPDAAAYGDAGSDTLGNTSRAVGGLSLPVLGRMGLGHVTAIQGVPPDPAPTAFHGRMAERSEGKDTTTGHWEMMGVVLRQGLRTFPGGFPPEIVEAFVRETGAPGVLGNTVASGTVIIQELGEEHQRTGKPIVYTSADSVFQVAAHTDTVPLETLYAWCRTARRILDPWRVARVIARPFVGAPGKYARTYDRKDFSMPPPATTVLERLVEAGVPVVGVGKIPDIFDRRGITEEIHTAGNADGLARTAALLDRVDRGLVFVNLVDFDMLYGHRNDPAGYARALEELDRALPAILDRLGPGDLLALTADHGCDPTTPSTDHSREHVPLLVYAPGRGGGDLGTRTTFADLGATVAEYFGVRSDVGTSFLAEVTR
What is the function of this protein?
Phosphotransfer between the C1 and C5 carbon atoms of pentose.
What are the official names of this protein?
Phosphopentomutase, Phosphodeoxyribomutase.
What is the protein family that this protein belongs to?
Belongs to the phosphopentomutase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIF2A_MOUSE
Sequence: MATANFGKIQIGIYVEIKRSDGRIHQAMVTSLNEDNESVTVEWIENGDTKGKEIDLESIFSLNPDLVPDEDIEPSPELPPPSSSSKVNKIVKNRRTVAAVKNDPPPRDNRVVGSARARPSQLPEQSSSAQQNGSVSDISPVQAAKKEFGPPSRRKSNCVKEVEKLQEKREKRRLQQQELREKRAQDVDATNPNYEIMCMIRDFRGSLDYRPLTTADPIDEHRICVCVRKRPLNKKETQMKDLDVITIPSKDVVMVHEPKQKVDLTRYLENQTFRFDYAFDDSAPNEMVYRFTARPLVETIFERGMATCFAYGQTGSGKTHTMGGDFSGKNQDCSKGIYALAARDVFLMLKKPNYKKLELQVYATFFEIYSGKVFDLLNRKTKLRVLEDGKQQVQVVGLQEREVKCVEDVLKLIDIGNSCRTSGQTSANAHSSRSHAVFQIILRRKGKLHGKFSLIDLAGNERGADTSSADRQTRLEGAEINKSLLALKECIRALGRNKPHTPFRASKLTQVLRDSFIGENSRTCMIATISPGMASCENTLNTLRYANRVKELTVNPAAAGDVHPIMHHPPSQIDDLETQWGVGSSPQRDDLKLLCEQNEEEVSPQLFTFHEAVSQMVEMEEQVVEDHRAVFQESIRWIEDEKALLEMTEEVDYDVDSYATQLEAILEQKIDILTELRDKVKSFRAALQEEEQASKQINPKRPRAL
What is the function of this protein?
Plus end-directed microtubule-dependent motor required for normal brain development.  May regulate microtubule dynamics during axonal growth.  Required for normal progression through mitosis.  Required for normal congress of chromosomes at the metaphase plate.  Required for normal spindle dynamics during mitosis.  Promotes spindle turnover.  Implicated in formation of bipolar mitotic spindles.  Has microtubule depolymerization activity (By similarity).
What are the official names of this protein?
Kinesin-like protein KIF2A, Kinesin-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. MCAK/KIF2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Lysosome. Note=Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1 (By similarity). Associated with lysosomes in NIH3T3 cells.