PharMolix/UniProtQA huggingface dataset:
Protein: EX7S_COXB1
Sequence: MPRKKTENFNFEASLNELTALVEKLEQGDLTLEESLQNFERGVGLVRSCQQALSDAEQKVKVLINQDGAETLVPFELETKTD
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 small subunit, Exodeoxyribonuclease VII small subunit, Exonuclease VII small subunit.
What is the protein family that this protein belongs to?
Belongs to the XseB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_PARP8
Sequence: MSLGLVGRKVGMTRIFTAEGDSIPVTVLDVSDNRVTQIKTVETDGYTAVQVAFGTRRASRVTKPLAGHLAKAGVQAGEILKEFQIDAAKAAELSSGAVIGVDLFEVGQKVDVQGTSIGKGYAGTIKRYNFSSGRASHGNSRSHNVPGSIGMAQDPGRVFPGKRMTGHMGDETVTVQNLEIARIDADRKLLLVKGAVPGAKGGKVFVTPAVKTRAVKGAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: Y397_STRS7
Sequence: MTAILVTGYRSFELGIFSEKDKRVAIIKKAIKRDLIAYLEEGVDWFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRATDFVKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFLSFERLNDIADE
What are the official names of this protein?
UPF0398 protein SZO_03970.
What is the protein family that this protein belongs to?
Belongs to the UPF0398 family.
Protein: METN1_YERPN
Sequence: MISIERLSKTYPQGGLPMVALEEVSLEIPTGSVFGIVGRSGAGKSTLIRCLNLLERPTSGRIQVDGRELTTLSDRELRLQRQNIGMIFQNFHLLHSRNVWDNIAVGLEIIGMPKAQRQQRVAELLDLVGLSDKAYAFPSQLSGGQKQRVGIARALAAKPSYLLSDEATSALDPETTASILALLSDINRQLGLTIVLITHELDVVKSICDNAALLETGRVVETGAIADLLSDPLSRLGRSLLPTCGPLSVSATPRAELTFFDTLAASPVLSALAQQHAVGVTLLGGGVEFIGGQRVGRLHVDFNRPEGGLNLAEVLQFLNDRGVRAELI
What is the function of this protein?
Part of the ABC transporter complex MetNIQ involved in methionine import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Methionine import ATP-binding protein MetN 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL2_TOLAT
Sequence: MAIVKCKPTSPGRRHVVKVVTPELHKGKPFAGLLEEKRKTGGRNNNGRITTRHIGGGHKQHYRLIDFKRNKDGIPAKIERLEYDPNRSANIALVLYADGERRYILAPKNLKAGDPIVSGVDAPIKAGNALPMRNIPVGTTVHAVEMKPGKGAQIARSAGASVQILAREGAYVTLRLRSGEVRKVLAECRATVGEVGNAEHMLRQLGKAGANRWRGIRPTVRGMAMNPVDHPHGGGEGRNKGIQPVSPWGTPAKGYRTRSNKRTDKYIVRRRNK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: INPA_EMENI
Sequence: MSHSMSSSSSSSSSSSSSRDEGQSRLNNVLSNIAKQCRTTSAQVQDVYPCTPLQQGLFALSLTSPGAYMAQHVFRLQPFVDQGRMKQAWNVVLQKHAILRTRIVMLGENAMQVVLKQSPEWRNCSDLRAYLDADQSITLQTGEPLTRWAISDTHLVWSAHHSVYDGFSVELILRDVATAYADGEIPPRPSFRQFIQRMFQQKQKSLTEAYWKKKTAHLDEVDTFPRLPASTYRPRPNSVYKHESSLAIDGPSGVTLSTIANAAWGLVQSSHLGSEQVSFGTTLSGRNANMPDIDKVVGPTLATVPVLLDVRSSQSVADFLQATQAYFTELIPHQHIGLQNLRRLNRATEAVCNFQTLFAFQPGMTETQGQSPYGHLLTAENKDKVEAAFYSYALTFQCSLAGTGIIKVLASYDDKIISSSQMKRLVFQFEHIVSQLISSNGSKRLSEIQLISPQDLDQLDIWKRKMESYEQLLPLDAIQRHIDTRPDATAVAAWDGTLSYVELDAFATRLATWLVHEQKVGPEIVIPICFDRSQWMIVSIFGVLKAGGAFLLLDPIYPENRLRYMIKMVNARTILVSESCRARFEGVPGAILAVNAAWFETHTHASIPMRELPVDRALYLVFTSGSTGQPKGVIVTHASYAASAAGHMPALGMNENTRQLFFASPAFDLSIYEILGSLMCGGTVCVPTEEDRNGSVAPVIRDMNVNLISLTSSYARHLRPEDVPRLETLALVGEPLARDVQRVWANRLTLINAYGPAECSVVSTVKRPVTLDSNPANIGTTVAGRAWVVHPKDHEILLPIGATGELLLEGDHLARGYLNDEEKTAAAYIFGPYWAPSPTPRRFYKTGDLVHFDEDGSIVFEGRKDSQVKIRGQRVEIAEIEHHLARLFPNAAGAAVDVFKHEYHVHLVAFLFCDKESWNSSDTPADILQRLGDVNVSTMSHIKQQLEQVMPHHMVPTRYQIWARMPTSLAGKLDRKALRKELGNQSTTVIELDETSTEFPVIDSTNKVALRLNHKILDLASEEKTTLDGRDFPLSILGLDSIQLITIVTFIRSEYGAKMTVETLYDLKLTVTGLAAMITSPHDRPAEAAPTLDLSKELQRVYRELTRRSESIKHKRKVFLTGATGLLGSQILRQLLADPSVQRVIVHVRANDAAKGMARVVSAATLAKWWSSSYANRVECWPGDLGMPQLGLQPEQWRMLCGTADAGAPITSVIHNGAAVQWQAPYQALKAVNVDSTVELLTAMAQWSEPGSFTFVSGGLKRSPGQDLESFMKSLEQANGYSQSKFVAEELVSRFAGHQSTHRVSIVRPGWVIGTEKDAVPNTDDFLWKLVQACIQIGAYPAEGGDLWLAVADAEEVATRILATTFAASGESPSVDNVEIGTTVSRFWELIKVQTGMELTQMSAEDWKQAAQDFAASQESEQTFLPVLAMLQDPQMEFGVQRPANGGPPSNVNAAIRSNIKTLVETGFLSDSSEVVIVED
What is the function of this protein?
Nonribosomal peptide synthase; part of the inp gene cluster that mediates the biosynthesis of fellutamide B, a mycotoxin that acts as a proteasome inhibitor (PubMed:18804170, PubMed:20952652, PubMed:27294372).  In the first step of fellutabmide B biosynthesis, inpC activates 3-hydroxydodecanoic acid to generate 3-hydroxydodecanoyl-AMP that is then loaded onto the T0 domain of inpB (PubMed:27294372).  The 3-hydroxydodecanoyl-S-phosphopantetheinyl-T0 is sequentially extended with L-Asn and L-Gln by the two CAT modules of inpB (PubMed:27294372).  The linear lipodipeptide from inpB is then transferred onto inpA for the addition of the third amino acid, L-Leu (PubMed:27294372).  Reductive releasing of the lipotripeptide by the TE domain of inpA produces (2S)-fellutamide B (PubMed:27294372).  InpF might be involved in the release and transfer of the lipodipeptide from inpB to inpA (PubMed:27294372).  The inp cluster-encoded proteasome subunit inpE confers resistance to internally produced fellutamides (PubMed:27294372).  The MFS efflux transporter inpD may contribute to fellutamide resistance as well (PubMed:27294372).
What are the official names of this protein?
Nonribosomal peptide synthase inpA, Fellutamide B biosynthesis cluster protein A, Inp cluster protein A, Interacting NRPS system protein inpA.
What is the protein family that this protein belongs to?
Belongs to the NRP synthetase family.
Protein: PANB_ECOL6
Sequence: MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFAEEGLNVMLVGDSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DERM_PIG
Sequence: QYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPSECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWMTTEYPGHYGEEMDMISYNYDYYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFANV
What is the function of this protein?
Seems to mediate adhesion by cell surface integrin binding.  May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment.  Enhances TGFB1 activity.  Inhibits cell proliferation (By similarity).  Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation.
What are the official names of this protein?
Dermatopontin, 22 kDa extracellular matrix protein, Dermatan sulfate proteoglycan-associated protein 22K, Tyrosine-rich acidic matrix protein, TRAMP.
What is the protein family that this protein belongs to?
Belongs to the dermatopontin family.
Protein: NP1L3_MOUSE
Sequence: MAEADPKMVTEPGAHGVAEEAMASTACDSGDESDSNSSSSTNSCSSSGSSSSGSSSSSSSSSSSSSSSSSSSSGSSGSSSNGSHLNRKKRVPEPSRRAQRRPSGKLFLDKLPQAVRNRVQALRNIQNECDKVDTLFLRAIHDLERKYAELNKPLYDKRFQIINAEYEPTEEECEWNSEEEFSGDEEMQDDTPNEMPPLEGEEEEESCNEKAEVKEEGTHVPEEVPEAKVEEEEAPKETPEVKTEEKDIPKEGAEEKAEEQESSKEIPEVKGEEKADSTDCIDIAPEEKEDVKEVTQANTENKDQPTEEFTPRAPAREAQKRVPETRPEEGVNIKRARKGKPKKEDPKGIPDYWLTVLKNVDKLGPMIQKCDEPILKFLSDVSLKFSNPGQPIGYTFEFHFLPNPYFRNELLMKTYIIRSKPDHYDPFFAWGWEIEECKGCKIDWRRGKDVTVTTTRSRPGITGEIEVQPRVVPNASFFNFFSPPEIPLIGKLEPREDAILDEDFEIGQILHDNVILKSIYYFTGEINDPYYHDFRDYGNRKYYK
What are the official names of this protein?
Nucleosome assembly protein 1-like 3, Brain-specific protein MB20.
What is the protein family that this protein belongs to?
Belongs to the nucleosome assembly protein (NAP) family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: IP5P1_ARATH
Sequence: MAEVRSRSRRTESNWATICCSAFSCLQLYWARIVLRKWFNVSASESDYSADSDDDYEDRSQEFDPISSGVTNPRVDTDGNVIYRPKLRRRNSETFRMQYIDTKAIRICAGTWNVGGRVPSSDLDIDGWLDTLEPADIYVLGLQEIVPLNAGNIFGMEDDQPALEWENLIRDALNRVQPRKLKIKSHSDPPSPSKFKQPEEVPYSVEDMFVETSHDACDGISSMDNKLNSVESTDVPIVSEDSLTNIDVLGSTNDNASCLPIQEYLQRQFSTPNTPDRSLSMQINSDSKREERFSYTERVGLSWPEPPLRLLNQYVSERRGSFKSVNLTITNLRKPSYVRIVSKQMVGVFLTIWVRRNLRKHISNLCVSTVGVGIMGYIGNKGSVSVSMSIYQTPFCFLCTHLSSGEKDTDQEKRNDDVREIHRRTQFLPHSLNANELPRSICNHERIIWLGDLNYRINLSYEKTHELIARKEWQRLVEYDQLSREMTKGNLFEGWSEGTLDFAPTYKYEIDSENYIGDDPESGKRRPAWCDRIIWNGKGMKLFNYRRNEIKLSDHRPVTATFLAEVEVLSPRKLQHALTLTYAEIQGLDA
What is the function of this protein?
Has phosphatase activity toward Ins(1,4,5)P3 and Ins(1,3,4,5)P4, but not toward Ins(1,4)P2, Ins(1)P (PubMed:11402208).  Seems to be involved in the abscisic acid (ABA) signaling pathway (PubMed:12805629).  Could also be able to hydrolyze PtdIns(4,5)P2 and PtdIns(3,4,5)P3 (PubMed:23658066).
What are the official names of this protein?
Type I inositol polyphosphate 5-phosphatase 1, At5PTase1.
What is the protein family that this protein belongs to?
Belongs to the inositol polyphosphate 5-phosphatase family.
Protein: UCRI_RHORU
Sequence: MAEAEHTASTPGGESSRRDFLIYGTTAVGAVGVALAVWPFIDFMNPAADTLALASTEVDVSAIAEGQAITVTWRGKPVFVRHRTQKEIVVARAVDPASLRDPQTDEARVQQAQWLVMVGVCTHLGCIPLGQKAGDPKGDFDGWFCPCHGSHYDSAGRIRKGPAPLNLPVPPYAFTDDTTVLIG
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
What are the official names of this protein?
Ubiquinol-cytochrome c reductase iron-sulfur subunit, Rieske iron-sulfur protein, RISP.
What is the protein family that this protein belongs to?
Belongs to the Rieske iron-sulfur protein family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS21_SYNJB
Sequence: MTQVTIGENEGIESALRRFKRQVSKAGILRDLRNHRHFETNLEKRKRKAVAVRRNRRKSMA
What are the official names of this protein?
30S ribosomal protein S21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: ARC_MYCTA
Sequence: MGESERSEAFGIPRDSPLSSGDAAELEQLRREAAVLREQLENAVGSHAPTRSARDIHQLEARIDSLAARNSKLMETLKEARQQLLALREEVDRLGQPPSGYGVLLATHDDDTVDVFTSGRKMRLTCSPNIDAASLKKGQTVRLNEALTVVEAGTFEAVGEISTLREILADGHRALVVGHADEERVVWLADPLIAEDLPDGLPEALNDDTRPRKLRPGDSLLVDTKAGYAFERIPKAEVEDLVLEEVPDVSYADIGGLSRQIEQIRDAVELPFLHKELYREYSLRPPKGVLLYGPPGCGKTLIAKAVANSLAKKMAEVRGDDAHEAKSYFLNIKGPELLNKFVGETERHIRLIFQRAREKASEGTPVIVFFDEMDSIFRTRGTGVSSDVETTVVPQLLSEIDGVEGLENVIVIGASNREDMIDPAILRPGRLDVKIKIERPDAEAAQDIYSKYLTEFLPVHADDLAEFDGDRSACIKAMIEKVVDRMYAEIDDNRFLEVTYANGDKEVMYFKDFNSGAMIQNVVDRAKKNAIKSVLETGQPGLRIQHLLDSIVDEFAENEDLPNTTNPDDWARISGKKGERIVYIRTLVTGKSSSASRAIDTESNLGQYL
What is the function of this protein?
ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle.  May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis.  Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
What are the official names of this protein?
Proteasome-associated ATPase, AAA ATPase forming ring-shaped complexes, ARC, Mycobacterial proteasome ATPase.
What is the protein family that this protein belongs to?
Belongs to the AAA ATPase family.
Protein: Y590_MYCPN
Sequence: MPITKATPLFLRYRLKGFVFLTLLLVQGVFTACAPAVPVNNKSVSAVQPEDKQALKPDPALGEYTSDLKFNTNFIPKKDDPFRPFYDLSFTLQFQDPYTATYGTGWLIDWKDNNQPNKFTAYIATNLHVADNLRNVNDYEFFNQFDYFDDPTESFTLGKFVDGNEIKQIVPDAMHEPSLVRIETSKLPKTAYTTTLFINDLGEYRLPAADFAVLESI
What are the official names of this protein?
Uncharacterized lipoprotein MPN_590.
What is the protein family that this protein belongs to?
Belongs to the MG067/MG068/MG395 family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RECA_SALA4
Sequence: MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPVYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGDNVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYNGEKIGQGKANATTWLKENPATAKEIEKRVRELLLSNQNATPDFAVDDSEGVAETNEDF
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH2_MYCA1
Sequence: MIRKSSGLRTLESALYRSGLGPVAGVDEVGRGACAGPLVVAACVLGPGKLESLAALDDSKKLTESVRERLFPVIRRYALAYHVVFIPPAEVDRRGVHVANIEGMRRAVAGLSLRPGYVLSDGFRVPGLAVPSLPVIGGDAVAACIAAASVLAKVSRDRLMVAMDAEHPGYGFADHKGYSTPAHSAALARLGPCPQHRHSFINVRRVANGSGGRVVADCKPDLPLQRDEGR
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IXTPA_BACHK
Sequence: MENMKQVVVATKNMGKVREFAELFERFDLEVKSLHDFPHIEEVEETGETFEENAILKADSLSRQLNAIVIADDSGLIVDALNGKPGVYSARFAGEPKDDQANIDKVLQELNEVAFEKRKARFYCALAVAFPEGDKKPVIVNGTCEGFILEQRRGENGFGYDPIFYVEEYKKAMAELSSDEKNAISHRGRALRKLEEKIPEWFLGE
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: NAGB_SALSV
Sequence: MRLIPLSTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPLTAYKALVEMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEGNVNHMWTISCLQLHPKAVVVCDEPSTMELKVKTLKYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: ODO1_EXISA
Sequence: MGESSNVHEKSQAFYGPNLGYIIELYEQYLEDPSSVDEETRRYFDEFGAPETSTPTEVPVSGPSFDLEKVVSATRLINDIRAFGHKAADIYPLKDHPREQELFELSRYDLTEEDLKQIPARLLSDDAPKPNASALELFRHLLDVYTGTVAIELRHLDDMEEKKWIRRQVEQGALQQTFSKEEKIELFKRLAETELFESFLHKTYVGQKRFSIEGLDAMVPLLDAMVGGLISSGSEHINIGMAHRGRLNVLAHVLGKPYEMIFAEFQHAPNKELIPSEGSIGINFGWSGDVKYHLGLDRKVVEQQKEVRLNLANNPSHLEFVGSVVEGYTRAAQDDRSEKGSAVQHDDLAASILIHGDAAFPGQGIVAETLNMTNLTGYRTGGTVHVIANNTIGFTTDPNDSRSTRYASDIAKGYEIPVFHVNADDPEACVAVAKLISEYRAKFHKDILVDLIGYRRYGHNEMDEPMNTNPVLYKAIKGHQSVRHVYAARLEEEGVMTKDEKAQIEQKIEEALKAARDLVPSEEEDADIVLPDAVHKGFPKVDTSVEREFLTQLNEELLNWPEGFGVFHKLQKVLDRRRDAFSEGGKIDWGHAETLAFASILSDGTPVRLSGQDSERGTFAQRNIMLNDVESGKKFSPLHELSTAKASFSVYNSPLSEGSVLGFEYGYNVFAQDTLVLWEAQYGDFANSAQVMFDQFISAGRAKWGQKSGLVMLLPHGYEGQGPEHSSARMERYLTLAGEKNWTVANLSSAAQYFHILRRQAEMLGKEEIRPMIIMTPKSLLRHPLATSPVEAFTEESFKPIVEQPGLGENTEKVERLVFCTGKMAIDLAEAVGKSEESLDFLHIVRVEEIYPFPVREIRDVISRYPNAREIVWVQEEPKNMGAWTYIEPRLEAVTTNRLDVRYIGRRRRSSPAEGNPTAHKQEQARIIREALSRDVVSSGAGTSTYQKDRK
What is the function of this protein?
E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
What are the official names of this protein?
2-oxoglutarate dehydrogenase E1 component, Alpha-ketoglutarate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the alpha-ketoglutarate dehydrogenase family.
Protein: YKI7_SCHPO
Sequence: MDQYRDLPKEDPDTAIEYESGVDEESSLKIEKFRVLIFGKDNSQDDLVKSVFNLSKLSEKEKMPFGIKCESEENPNFESYHSKVGKKSCKRFMRWLKANAFAEERDIDCIWYQLNLLDISDEDILCLQYLQGCLIPIVSIIYDFNEFLSPFTKSFLSKIGESNTITVKGMPLADVLVFRKKVLKLVSQLSFMTDRKELVYTTCLALEDDDAYTNFVSAQQEDSSCKFYGGILIGVSHCKYAAAGASYPLPIPASGLLAQKLAIGLLCKDIIKLWNLCPESSILTKEILLELPKASDVAKSIGKMILTSMFVPLWLLKGIWEAPATAKIIIGSIADVTLPVQRMYYFIKAGGKLDVPTIHAFYQHYKEFVRPKCLEHIAEITTFNVVTAFSSEAVYQEAIRLLDRFRYVSKSSEEDLIVPSFVVNDLITYD
What are the official names of this protein?
Uncharacterized protein C630.07c.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: TIG_RHOPT
Sequence: MQVKETVADGLKREFQVNVPAADIDAKIDEKLADLKDKVRLNGFRPGKVPTAHLKRVYGRSVAAETIDKLVRDTNDGIFSERGFRLATEPKITMPQDQKEIEDILEGKSDLTYTVAIEVVPAIELADFKSFSVEKPVVDVADSDVDEAIKRIADANRAYADKAEGAKAETGDRVTVSFKGTIDGVAFDGGTGEDIPVVIGSASFIPGFEDQLVGIAVGETRTIKVTFPANYASETLAGKPAEFETTATKLEAPQETTIDDEFAKTLGLESLDKLKEAAKARLGAEYAGASRLKVKRQLLDRLDEAHKFDAPPSLIEQEFEVMWRSINAEMQSTGKTFADENTTEDAAKEEYRKIADRRVRLGLVLSEIGEKNKIQVTDDEVSRAVIERARQMPGREKEVWDFYRSNPEALAQLRAPIYEDKVVDFILELANVTEKKVTREELYKDEDDKTAA
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: ARGR_CHLCH
Sequence: MNKQARHFKIREILQRHSVENQHDLLQLLREQGMSVAQATLSRDCAELGLMRVRVNGSYRMVVPDDNAGRIIKGLVGIEVLSINANETTVIIRTLPGRAHGVGSYLDQLKSPLVLGTIAGDDTVLVIPASVHNISSLIAYIHSNLSKT
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL8_CAEEL
Sequence: MGRRIRIQRKGAGGIFKSHNKHRKGASKLRPLDYAERHGYIKGLVKDIIHDPGRGAPLAIIAFRDPYKYKTVKTTVVAAEGMHTGQFIHCGAKAQIQIGNIVPVGTLPEGTTICNVENKSGDRGVIARASGNYATVIAHNPDTKKTRIRLPSGAKKVVQSVNRAMIGLVAGGGRTDKPLLKAGRSYHKYKAKRNSWPRVRGVAMNPVEHPHGGGNHQHIGHPSTVRRDASAGKKVGLIAARRTGRIRGGKPVKFTKEENV
What are the official names of this protein?
60S ribosomal protein L8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 6PGL_SCHPO
Sequence: MSVYSFSDVSLVAKALGAFVKEKSEASIKRHGVFTLALSGGSLPKVLAEGLAQQRGIEFSKWEVFFADERIVPLDDENSNYALCKKLIFDKFEGFDPKKIHTINPELLKENPIDPQNVADEYEKQLVHVFANSSTVKVPVFDLLLLGCGPDGHTCSLFPDHEVLQEDVAWVAPVTDSPKPPKDRITLTLPVVTHAQAIAFVTTGAGKKDILPIVIEDFTSKLPSALITRNNLTRTSWFVDDEASANLERSSLKVFPQ
What is the function of this protein?
Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
What are the official names of this protein?
Probable 6-phosphogluconolactonase, 6PGL.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein: CAZA2_MONDO
Sequence: MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEEQVLITEHGDLGNGKFLDPKNRVSFKFDHLRKEATDPRPYEGENAIESWRHSVETAMRAYVKEHYPNGVCTVYGKTIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA
What is the function of this protein?
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends.  Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity).
What are the official names of this protein?
F-actin-capping protein subunit alpha-2, CapZ alpha-2.
What is the protein family that this protein belongs to?
Belongs to the F-actin-capping protein alpha subunit family.
Protein: RK32_STIHE
Sequence: MAVPKKRTSKSKKNLRKNTWKKKVLKRAMRALFIAKLDLNNLQDNVATLEDSNETSS
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UB2FB_MOUSE
Sequence: MLTLASKLKWDEDLKGSQTSVSTSDSTRRFSMRDKLLVTEVAELEANLPWTCKVHFPDPNKLHCFQLTVSPDEGYYQGGNFQFEIEVPDAYNMVPPKVKCLTKIWHPNITETGEICLSLLREHSADGTGWAPTRTLKDVVWGLNSLFTDLLNFYDPLNIEAAEHHLQDKEDFRDKVDEYIRRYAR
What is the function of this protein?
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins.  The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.
What are the official names of this protein?
NEDD8-conjugating enzyme UBE2F-B, NEDD8 carrier protein UBE2F-B, NEDD8 protein ligase UBE2F-B, RING-type E3 NEDD8 transferase UBE2F-B, Ubiquitin-conjugating enzyme E2 F-B.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family. UBE2F subfamily.
Protein: RL17_AEDAE
Sequence: MGRYAKEPDNPAKSCKARGSNLRVHFKNTRETALAIKRMPLRRAQKFLKNVCEKKECVPFRRFNGGVGRCAQAKHWNTSVGRWPKKSAEFLLQLLKNAEANADYRGLDVDRLVVDHIQVNRAPCLRRRTYRAHGRINPYMSSPCHIELSLTEKEDVVTKAAENEPAKKKLSKKKLQRQKEKMMRNE
What are the official names of this protein?
60S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: AROE_SHISS
Sequence: METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFINTLNAFFRAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTDGVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAKLFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKGKTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKLLQQELSA
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.