PharMolix/UniProtQA huggingface dataset:
Protein: EX7L_CLOTE
Sequence: MYIKVLSVTDINNYIKNTMDNDFILNNASIRGEISNFKIHSSGHVYFSMKDQWSKINCVMFRSAAKGLKFLPEDGMKIIANGRISAYVKDGSYQLYCDKLELEGLGELYIAFEKLKNKLEKEGLFKEECKKSLPQYAKKIGVITSETGAAIRDIINVATRRNKNCEILIYPSLVQGTNASSDIIKGIKELNKVKDLDVIILARGGGSIEELWVFNDEELAREIFKSKVPIITGVGHETDFTIADFVSDKRAPTPSAAAEIAIKDLQELNSRLENYKNALNYYVLNNLKEKYNKLDRLKLSMEGNSPERIIINEYNKIDFIINKLNSYIKIEVDKRKEELSRMSILLSSNNPLNILNKGYSVIQDGTGKVINTIKELDKEKKVTINLKDGKKEYQIQ
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL20_BURCM
Sequence: MPRVKRGVTARARHKKIIKLAKGYRGRRNNVYRIAKQAVMRAGQYAYRDRRNKKRVFRALWITRINAAVRQHDMTYSVFINGLKKASIELDRKVLADMAVFDKAAFAAIVQQVKAAVAA
What is the function of this protein?
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit.  It is not involved in the protein synthesizing functions of that subunit.
What are the official names of this protein?
50S ribosomal protein L20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL20 family.
Protein: TDH_BURM9
Sequence: MKALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTVGVGVNREGAFAEYLAIPAFNAFKIPPEISDDLAAIFDPFGNATHTALSFNLVGEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLELARKMGATRAVNVSRESLRDVMADLHMTEGFDVGLEMSGVPSAFTSLLESMNHGGKVALLGIPPAQTAIDWNQVIFKGLEIKGIYGREMFETWYKMVAMLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVILDWADA
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: XERD_ECOL6
Sequence: MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRGLTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLASPKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDISLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQMTRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates.  The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.  In the complex XerD specifically exchanges the bottom DNA strands (By similarity).
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_PASMU
Sequence: MNDKDHFSSPAHITVLLNEAVAGLALKEKGIYIDGTFGRGGHSRLILSRLADNGRLIAIDRDPRAIAEAKTIQDPRFHIEHRSFSDIPRICERLNLVGKVDGILLDLGVSSPQLDEAERGFSFMKDGPLDMRMDTTQGLSASEWLQQVSEQDLAWVLKTFGEERFAKRIAQAIVNYNKQALQHGTEPLSRTLQLAELIANAVPFKDKHKHPATRSFQAIRIFINAELDELESVLKSAVQVLAPQGRLAIISFHSLEDRMVKHFMRKQSKGEDIPKGLPLRDDQIQRTQTLKVIGKAIMPTEQEQQQNPRSRSAVLRVAEKL
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y2304_CLOB1
Sequence: MHYCNKDIGSFGETIAVDYIKNCGYIILERNFRCKLGEIDIIAKDKNFIVFIEVKTRYSYIYGSPSEAITFRKQNKIYKTAQLYIIKKAIHNKFYFRFDVIEVILNTLNSNYSVKLIKNAFQI
What are the official names of this protein?
UPF0102 protein CLB_2304.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: TBC3B_HUMAN
Sequence: MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
What is the function of this protein?
Acts as a GTPase activating protein for RAB5.  Does not act on RAB4 or RAB11 (By similarity).
What are the official names of this protein?
TBC1 domain family member 3B.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor. Note=Associated with lipid rafts.
Protein: YBEY_SULSY
Sequence: MKNKTQKNRILINKEVYSKEITKKFLKDITEKILSELNLNNVEISITLTDNERIREINKEWRGKDKPTDVLSFPQDETIGYKYRLLGDVIISLPYAKAQAEEIGLTLREEVLRLLVHGILHLLGYDHETNEEDAKIMFDLQDKIFDKLTCEL
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTG_STAAC
Sequence: MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSMPSGVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEELIDTQKEFAMLAAKSIANHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDTRAEQQSTSGTSFRQILEEDENTDYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLSHVSPTIKDMIERFVHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIPSDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK
What is the function of this protein?
Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.
What are the official names of this protein?
Formimidoylglutamase, Formiminoglutamase, Formiminoglutamate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the arginase family.
Protein: DAPB_CHLCH
Sequence: MKFTLIGNGRMGQQVAHIINNSSAHSIAAILDVDATITPEVFHGSDAIIDFTVRHAFLENLPAMVASGVPIVVGTTGWDDVQADVRQQIAAANTSLLYSANFSLGVNIFMRIVREAARMIEPFSHFDIALTEQHHTGKADFPSGTALRTAQMVLAANSRKTSIVRELADGNKLTPNELHVASLRLGTIFGKHSAFIDSETDDIEISHTAKSRSGFAAGAVEAAAWLALRHTTAPGFYTMDDFLDEKLGK
What is the function of this protein?
Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate reductase, HTPA reductase.
What is the protein family that this protein belongs to?
Belongs to the DapB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YJJQ_ECOLI
Sequence: MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDLTLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLMCPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERKVLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELNLPSVYGDAAEWNTAELRREMSHS
What are the official names of this protein?
Putative transcription factor YjjQ.
Protein: CXA8_MOUSE
Sequence: MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHHVRMEEKRKDREAEELCQQSRSNGGERVPIAPDQASIRKSSSSSKGTKKFRLEGTLLRTYVCHIIFKTLFEVGFIVGHYFLYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVAFVSLFLNIMEMSHLGMKGIRSAFKRPVEQPLGEIAEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLSAKPFSQFEEKIGTGPLADMSRSYQETLPSYAQVGVQEVEREEPPIEEAVEPEVGEKKQEAEKVAPEGQETVAVPDRERVETPGVGKEDEKEELQAEKVTKQGLSAEKAPSLCPELTTDDNRPLSRLSKASSRARSDDLTI
What is the function of this protein?
Structural component of eye lens gap junctions (PubMed:1325220).  Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells.  They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity).  Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (PubMed:1325220).
What are the official names of this protein?
Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70.
What is the protein family that this protein belongs to?
Belongs to the connexin family. Alpha-type (group II) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: SYS_STRGC
Sequence: MLDLKRIRTDFDTVAAKLATRGVDAATLNQMKTIDKERRDLLVKVEELKAERNTVSAEIAQAKRNKENADDKIAAMQKLSAEVKNLDATLAELDAKLTEFTTTLPNIPHESVPVGADEDENVEVRRWGTPRQFDFEAKAHWDLGEDLDILDWERGAKVTGARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYMVNHDSMFGTGQYPKFKEDTFELSDTNFVLIPTAEVPLTNYYRDEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTVAAILENYQNEDGSVTIPEVLRPYMGGLEVIAPK
What is the function of this protein?
Catalyzes the attachment of serine to tRNA(Ser).  Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
What are the official names of this protein?
Serine--tRNA ligase, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GBRG4_CHICK
Sequence: MPAMVLLLCLALGPALRSARCESTEEYDYDYLSINKTWVLTPKAQETDATQILNSLLKNYDNKLRPDIGIKPTFIDVDIYVNSIGPVSVIQMEYTIDIFFAQTWYDRRLRFNSTLKALTLNTNMVSRIWIPDTFFRNSKRADSHWITTPNQLLRIWNDGKVLYTLRLTIEAECLLQLQNFPMDTHSCPLVFSSYGYPREEIVYRWRRYSIEVSDQRTWRLYQFDFTGLRNTSEVLRTGAGEYMVMTVSFDLSRRMGYFAIQTYIPCILTVVLSWVSFWIKRDSTPARTSLGITTVLTMTTLSTISRKHLPRVSYITAMDLFVSVCFIFVFAALMEYATLNYLVGNKKPLEHSSRKARLPPAGAQVMPSFTAINININNIMHWPPEIEEDEDDDPGSPCLEGKECERFFCCIEDCQTGMWREGRVRIHISRLDSYSRVFFPTAFLLFNIVYWIAYLYL
What is the function of this protein?
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
What are the official names of this protein?
Gamma-aminobutyric acid receptor subunit gamma-4, GABA(A) receptor subunit gamma-4.
What is the protein family that this protein belongs to?
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG4 sub-subfamily.
What are the subcellular locations of this protein?
Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein: EFTU_FERIS
Sequence: MAKVTFVRTKPHMNVGTIGQIDHGKTTLTAAITKYCSFFGWADYTPYEMIDKAPEERARGITINITHVEYQTEKRHYAHIDCPGHADYIKNMITGAAQMDGAILVLAATDGPMPQTREHVLLARQVNVPAMIVFINKVDMVDPELVDLVEMEVRDLLSKYEFPGDEVPVVRGSALKAIEAPNDPNDPAYKPIKELLDAMDTYFPDPVREVDKPFLMPIEDVFSITGRGTVVTGRIERGVIKPGVEAEIIGMSYEIKKTVITSVEMFRKELDEAIAGDNVGCLLRGSSKDEVERGQVLAKPGSITPLKKFKANIYVLKKEEGGRHTPFTKGYKPQFYIRTADVTGEIVDLPAGVEMVMPGDNVEMTIELIYPVAIEKGMRFAVREGGRTVGAGVVSEIIE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FBX16_MOUSE
Sequence: MMAFAPPKSIDGPKMQTKMSTWTPLNHQLLNDQVFEERRALLGKWFDKWTDSQRRRILTGLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSVYIFSFLDPRSLCRCAQVSWYWKSLAELDQLWMLKCLRFNWYISFSPTPFEQGVWKKHYIQMVRELHVTKPKTPPKDEFTTADVQPIPGNSPDEKQSPSLAFRSSSSLRKKNNPGEKELPPWRSSDKHPTDIIRFNYLDNCDPELFRLGRRKRSEVTPDFKRQLRDKKNKLQDRARLRKAQSLISLSSPPKVPVRLAWPLHLPVAPSDREAATEALLEHLQKHPGLQSPSPRLQSQS
What is the function of this protein?
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
What are the official names of this protein?
F-box only protein 16.
Protein: ISPD_ACIBC
Sequence: MRHLHHQTSQTKLWAVIPAAGSGSRFSKTELKQYQYIQDATVIEHTVKRLSQLPLTGYVLAIGKQDTFASTLSFQDKHKAHFCNGGVERVHSVLNALNYLSQIADEDDWVLVHDAARPCVTFECLNTLVKNAIETNQSAILAIPVRDTLKQVNQEQQIDKTVSRELLWQAQTPQIAKIGILKKAIETALKNNLTITDEASALESIGESVLVVMGRSDNIKITYPDDLELARLILQSQN
What is the function of this protein?
Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, MEP cytidylyltransferase, MCT.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
Protein: SYH_SCHPO
Sequence: MFVFTKNLFTTKFSSSLLNWRFLRTMADSLVDINERITSQGNLVRSLKSQGASKEDIDKEVAKLLQLKNLKLGGSEVSGKKKDTSFTLKTPKGTKDWCDKDVVLREHIFSTVTEIFKRHGGVTLDTPVFELKEILSGKYGEDSKLIYDLKDQGGELCSLRYDLTVPFARWLAMNPKVTSIKRFHIAKVYRRDQPAMTKGRMREFYQCDFDIAGNYDPMIPDSEALKVLVEALDALEVGNYTIKLNHRKILDGIFTVCGVPDDKIRTISSAVDKLDKLPWEDVRREMVVEKGLKEEVADKIKEYVLLKGDRSLLDKLEADSLLSSNSSAVAAFNDMRLLFDYLEAFGVLDRFSFDMSLARGLDYYTGIIYEAVTEASAPKIKSSAEKKKSADPEADRSNDDSIGVGSIAAGGRYDNLVGMFAAKKNAKIPCVGISLGLERIFSILRSKIPDEDIRANDVDVFVMAFGGGKEWTGFLKERMSVCKDLWANGIKAEFLYKVKPKPRQQFDAADKFDVPFAVILGQDEFAKGSVRIKQMGLKENSDEGQLVPREEMVSVLKKLLKYD
What is the function of this protein?
Catalyzes the aminoacylation of histidyl-tRNA in both the cytoplasm and the mitochondrion.
What are the official names of this protein?
Histidine--tRNA ligase, mitochondrial, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm.
Protein: VKTN1_CYRHA
Sequence: MGIARILSAVLFLSVLFVVTFPTLLSADHHDGRIDTCRLPSDRGGCKASFERWYFNGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA
What is the function of this protein?
Serine protease inhibitor that inhibits trypsin and blocks voltage-gated potassium channels (Kv).
What are the official names of this protein?
Kunitz-type U15-theraphotoxin-Hhn1n, U15-TRTX-Hhn1n, Kunitz-type serine protease inhibitor hainantoxin-XI-14, HNTX-XI-14.
What is the protein family that this protein belongs to?
Belongs to the venom Kunitz-type family. 01 (intermediate) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PHNX_ALISL
Sequence: MQDSPVQAVIFDWAGTIVDFGSFAPTSIFVEAFKSGFNFDINLAEAREPMGLGKWQHIEAVGKLPSVNQRWHQQFGHAMTSEEIDHIYATFMPLQKAKVADHAEPILNAIDVVNDLKDKGIKIGSCSGYPREVMDILIPAAAKYGYHPDYVVATDDLPQGGRPAAFMALKNAIELGVTNVSTCIKVDDAAPGIDEGHNAGMWTVGLLLSGNEAGLTYEEYQAADAETLSVAREKARLKLQKSTPHYLIDTIADLPEVIADIETRLLAGERP
What is the function of this protein?
Involved in phosphonate degradation.
What are the official names of this protein?
Phosphonoacetaldehyde hydrolase, Phosphonatase, Phosphonoacetaldehyde phosphonohydrolase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. PhnX family.
Protein: YRF17_YEAST
Sequence: MEIENEQICTCIAQILHLLNSLIITFLDDDKTETGQSFVYIDGFLVKKHNNQHTIVNFETYKNKMKVSDRRKFEKANFDEFESALNNKNDLVHCPSITLFESIPTEVRSFYEDEKSGLIKVVKFRTGAMDRKRSFEKIVVSVMVGKNVQKFLTFVEDEPDFQGGPIPSKYLIPKKINLMVYTLFQVHTLKFNRKDYDTLSLFYLNRGYYNELSFRVLERCYEIASARPNDSSTMRTFTDFVSGTPIVRGLQKSTIRKYGYNLAPYMFLLLHVDELSIFSAYQASLPGEKKVDTERLKRDLCPRKPTEIKYFSQICNDMMNKKDRLGDILHIILRACALNFGAGPRGGAGDEEDRSITNEEPIIPSVDEHGLKVCKLRSPNTPRRLRKTLDAVKALLVSSCACTARDLDIFDDNNGVAMWKWIKILYHEVAQETALKDSYRITLVPSSDGVSVCGKLFNREYVRGFYFACKAQFDNLWEELNDCFYMPTVVDIASLILRNREVLFREPKRGIDEYLENDSFLQMIPVKYREIVLPKLRRDTNKMTAALKNKVTVAIDELTVPLMWMIHFAVGYPYRYPELQLLAFAGPQRNVYVDDTTRRIQLYTDYNKNGSSEPRLKTLDGLTSDYVFYFVTVLRQMQICALGNSYDAFNHDPWMDVVGFEDPDQVTNRDISRIVLYSYMFLNTAKGCLVEYATFRQYMRELPKNAPQKLNFREMRQGLIALGRHCVGSRFETDLYESATSELMANHSVQTGRNIYGVDSFSLTSVSGTTATLLQERASERWIQWLGLESDYHCSFSSTRNAEDVVAGEAASSDHHQKISRVTRKRPREPKSTNDILVAGQKLFGSSFEFRDLHQLRLCHEIYMADTPSVAVQAPPGYGKTELFHLPLIALASKGDVKYVSFLFVPYTVLLANCMIRLSRCGCLNVAPVRNFIEEGCDGVTDLYVGIYDDLASTNFTDRIAAWENIVECTFRTNNVKLGYLIVDEFHNFETEVYRQSQFGGITNLDFDAFEKAIFLSGTAPEAVADAALQRIGLTGLAKKSMDINELKRSEDLSRGLSSYPTRMFNLIKEKSEVPLGHVHKIWKKVESQPEEALKLLLALFEIEPESKAIVVASTTNEVEELACSWRKYFRVVWIHGKLGAAEKVSRTKEFVTDGSMRVLIGTKLVTEGIDIKQLMMVIMLDNRLNIIELIQGVGRLRDGGLCYLLSRKNSWAARNRKGELPPIKEGCITEQVREFYGLESKKGKKGQHVGCCGSRTDLSADTVELIERMDRLAEKQATASMSIVALPSSFQESNSSDRCRKYCSSDEDSDTCIHGSANASTNATTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSSTNATTTASTNVRTSATTTASINVRTSATTTESTNSNTSATTTESTDSNTSATTTESTDSNTSATTTASTNSSTNATTTASTNSSTNATTTESTNASAKEDANKDGNAEDNRFHPVTDINKESYKRKGSQMVLLERKKLKAQFPNTSENMNVLQFLGFRSDEIKHLFLYGIDVYFCPEGVFTQYGLCKGCQKMFELCVCWAGQKVSYRRMAWEALAVERMLRNDEEYKEYLEDIEPYHGDPVGYLKYFSVKRGEIYSQIQRNYAWYLAITRRRETISVLDSTRGKQGSQVFRMSGRQIKELYYKVWSNLRESKTEVLQYFLNWDEKKCREEWEAKDDTVFVEALEKVGVFQRLRSMTSAGLQGPQYVKLQFSRHHRQLRSRYELSLGMHLRDQLALGVTPSKVPHWTAFLSMLIGLFCNKTFRQKLEYLLEQISEVWLLPHWLDLANVEVLAADNTRVPLYMLMVAVHKELDSDDVPDGRFDILLCRDSSREVGE
What is the function of this protein?
Catalyzes DNA unwinding and is involved in telomerase-independent telomere maintenance.
What are the official names of this protein?
Y' element ATP-dependent helicase protein 1 copy 7.
What is the protein family that this protein belongs to?
Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily.
Protein: ATPA_WOLSU
Sequence: MQADEISSIIKERIDNFELDVNVAETGKVMAFADGVAKVYGLKNVMSYEMVEFDTGDRGLASNLEESSVGVVVLGAGKNIKEGTSVKRLGKLMKVPAGDALMGRVVNGMGEPVDGKGAIETTEYRFVEEKAPGIMQRKSVHEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTVAIDTIINQKGQDVVCIYVAIGQKESTVAQVVRKLEEHGAMEYTIIVNAPASDSAAMQFLAPYTGVTMGEYFRDNARHALIIYDDLSKHAVAYREMSLILRRPPGREAFPGDVFYLHSRLLERAAKVSDELGAGSLTALPIIETQAGDVAAYIPTNVISITDGQIFLETDLFNSGVRPAINVGLSVSRVGGAAQIKATKQVAGTLRLDLAQYRELQAFAQFASDLDESSRKQLERGQRMVEILKQPPYAPLPIERQVVVIFAGAKGYMDDISVTKITKFEAELYPFIEAKYPQIFEDIRTKKMIDKETEETLSKALEEFKTVFVA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: TRMD_BACSU
Sequence: MKIDFLTLFPEMFEGVLGSSILQKAQEKDAVQFQVVNFREYSDNKHNTVDDYPYGGGAGMVLKPQPVFDAVEDLTSKAAAAPRIILVCPQGERFTQKKAEQLAKEEHLLFICGHYEGYDERIREHLVTDEISIGDFVLTGGELPAMMIADSVVRLLPGVLGKEASHIEDSFSTGLLEHPHYTRPADYKGLKVPETLLSGNHAKIEEWRNKESIRRTYLRRPDLLKDHPLTEQQRKWISEWEKE
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBH_AQUAE
Sequence: MTKKEIAEEIYDRLIRDYNVKIQKKEVYNLVSEVFTIIQECLLKGEKVKISGFGTFVVKTRKPKKGMNIKKREIVEVPERKIVLFKPSKNFIKS
What is the function of this protein?
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
What are the official names of this protein?
DNA-binding protein HU.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: Y2204_STAAM
Sequence: MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDSRILEALVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
What are the official names of this protein?
Uncharacterized hydrolase SAV2204.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily.
Protein: MED18_HUMAN
Sequence: MEAPPVTMMPVTGGTINMMEYLLQGSVLDHSLESLIHRLRGLCDNMEPETFLDHEMVFLLKGQQASPFVLRARRSMDRAGAPWHLRYLGQPEMGDKNRHALVRNCVDIATSENLTDFLMEMGFRMDHEFVAKGHLFRKGIMKIMVYKIFRILVPGNTDSTEALSLSYLVELSVVAPAGQDMVSDDMKNFAEQLKPLVHLEKIDPKRLM
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
What are the official names of this protein?
Mediator of RNA polymerase II transcription subunit 18, Mediator complex subunit 18, p28b.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 18 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MMP9_CANLF
Sequence: MSPRQPLVLVFLVLGCCSAAPRPHKPTVVVFPGDLRTNLTDKQLAEEYLFRYGYTQVAELSNDKQSLSRGLRLLQRRLALPETGELDKTTLEAMRAPRCGVPDLGKFQTFEGDLKWHHNDITYWIQNYSEDLPRDVIDDAFARAFAVWSAVTPLTFTRVYGPEADIIIQFGVREHGDGYPFDGKNGLLAHAFPPGPGIQGDAHFDDEELWTLGKGVVVPTHFGNADGAPCHFPFTFEGRSYSACTTDGRSDDTPWCSTTADYDTDRRFGFCPSEKLYAQDGNGDGKPCVFPFTFEGRSYSTCTTDGRSDGYRWCSTTADYDQDKLYGFCPTRVDSAVTGGNSAGEPCVFPFIFLGKQYSTCTREGRGDGHLWCATTSNFDRDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYSFTEGPPLHEDDVRGIQHLYGPRPEPEPQPPTAPPTAPPTVCATGPPTTRPSERPTAGPTGPPAAGPTGPPTAGPSEAPTVPVDPAEDICKVNIFDAIAEIRNYLHFFKEGKYWRFSKGKGRRVQGPFLSPSTWPALPRKLDSAFEDGLTKKTFFFSGRQVWVYTGTSVVGPRRLDKLGLGPEVTQVTGALPQGGGKVLLFSRQRFWSFDVKTQTVDPRSAGSVEQMYPGVPLNTHDIFQYQEKAYFCQDRFYWRVNSRNEVNQVDEVGYVTFDILQCPED
What is the function of this protein?
Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration (By similarity).  Could play a role in bone osteoclastic resorption (By similarity).  Cleaves KiSS1 at a Gly-|-Leu bond (By similarity).  Cleaves NINJ1 to generate the Secreted ninjurin-1 form (By similarity).  Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments.  Degrades fibronectin but not laminin or Pz-peptide (By similarity).
What are the official names of this protein?
Matrix metalloproteinase-9, MMP-9, 92 kDa gelatinase, 92 kDa type IV collagenase, Gelatinase B, GELB.
What is the protein family that this protein belongs to?
Belongs to the peptidase M10A family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: ECHD1_BOVIN
Sequence: MELKQEMASLLKTSPNAVKKRLLHQIGLSLYNTSHGFHEEEVKKKLEQFPGGSIDLQKENSGIGILTLNNPSKMNAFSGVMMLQLLEKVIELENWTEGKGLIIRGAKNTFSSGSDLNAVKALGTPEDGMAVCMFMQNTLTRFMRLPLISVALVQGRALGGGAEVTTACDFRLMTTESEIRFVHKEMGIIPSWGGATRLVEIIGGRQALKVLSGALKLDSEKALNIGMVDDILPSSDETECLKEAQEWLQQFIKGPPEVIRALKKSVSSCKELCLEEALQRERDILGTVWGGPANLEAVARKGKFNK
What is the function of this protein?
Decarboxylates ethylmalonyl-CoA, a potentially toxic metabolite, to form butyryl-CoA, suggesting it might be involved in metabolite proofreading.  Also has methylmalonyl-CoA decarboxylase activity at lower level.
What are the official names of this protein?
Ethylmalonyl-CoA decarboxylase, Enoyl-CoA hydratase domain-containing protein 1, Methylmalonyl-CoA decarboxylase, MMCD.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.