PharMolix/UniProtQA huggingface dataset:
Protein: RB40L_HUMAN
Sequence: MSAPGSPDQAYDFLLKFLLVGDRDVGKSEILESLQDGTAESPYSHLGGIDYKTTTILLDGQRVKLKLWDTSGQGRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHAPGVPKILVGNRLHLAFKRQVPREQAQAYAERLGVTFFEVSPLCNFNIIESFTELARIVLLRHRLNWLGRPSKVLSLQDLCCRTIVSCTPVHLVDKLPLPIALRSHLKSFSMAKGLNARMMRGLSYSLTTSSTHKRSSLCKVKIVCPPQSPPKNCTRNSCKIS
What is the function of this protein?
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
What are the official names of this protein?
Ras-related protein Rab-40A-like, Ras-like GTPase.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm. Mitochondrion.
Protein: C3H59_ORYSJ
Sequence: MAAAAASPSPATPPRILLAGDANGRLHQLFKRVTSVNQSTGPFHALLCVGQFFSPDAGDGDGGGGGEVADYLEGRAAVPIPTYFTGDYGPAAPRLLAKAASSARGFSPGGIQICPNLFWLRGSARFTLHGLSVVYLSGRKGPGGPGCYSQDDVDALRALAEEPGIVDLFLTNEWPAGVVNGVDTSNAPSQISDPHGYDPVVAELVAEIKPRYHIAGSKGVFYAREPYVSDSAAHVTRFIGLANVGNKEKQKFIHAISPTPASTMSSVDIHARPPNTTLSPYISPAKSVPVEETPKRPAEDADLQYWRYDVKKQRHGEAGGNRLCFKFTSSGSCPRGSKCNYRHDEEAREHYNRNVCFDFLNKGKCEKGPECRFAHSLSDEGAVRDTKPRSERRRVESSCWFCLSSPDVESHLVISIGEGYYCALAKGPLVPNHVLVIPVEHCSSTLKMPVEAEAELGRYKDALAKYFEKQGKIAIYFEWVSQQSRHANLQAVPVPLSKASSVKKIFHLAAQRLGFEFSVVNPDGDANRARELLRSECDSKSSLFYVELPEGSVLLHLVDSNEKFPAQFGREVLAGLLSMADRADWRNCKVSKEEEIQMVDDFKQGFREFDPAE
What are the official names of this protein?
Zinc finger CCCH domain-containing protein 59, OsC3H59.
Protein: SUTA_PSEAB
Sequence: MSEEELEQDELDGADEDDGEELAAADDGEADSSDGDEAPAPGKKAKAAVVEEELPSVEAKQKERDALAKAMEEFLSRGGKVQEIEPNVVADPPKKPDSKYGSRPI
What is the function of this protein?
Causes widespread changes in gene expression, and plays a direct role in the regulation of genes encoding ribosomal components.  Associates with chromosomal DNA through interaction with RNA polymerase.  Contributes to biofilm formation and secondary metabolite production.  Important during transitions to and from the survival state.
What are the official names of this protein?
Transcriptional regulator SutA, Survival under transitions A.
Protein: TRUB_BLOFL
Sequence: MQRYVNFFDKNRRDVHGLLLLDKPTGFSSSFFLNKIKKLFYAKKVGYIGTLDPIATGMLPICFGKATKFASYLLNSDKRYRVLVKLGESTDTFDASGVIIRIADVQCNKEKIEECLKSFLGTSLQIPPMFSSLKYQGLPLYKYARRGVNIPRKSRTIHVYSLYCLNQLNSIIELEIHCSKGTYVRSIVNDIGEYLGCGAHIISLRRLMVGQYIASMMVNIKTIESIFFDKDLNDLEVLDKLDNLLISTETIMCSF
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: RS9_VIBCH
Sequence: MAENQYYGTGRRKSSAARVFIKPGSGNIVINKRSLEEYFGRPTSCMVVKQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRPVLRAAGYVTRDARRVERKKVGLRKARRRPQFSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RLMN_STRP1
Sequence: MKPSIYSLTRDELIAWAVERGQKQFRATQIWDWLYKKRVQSFEEMTNISKDFVSILNDSFCVNPLKQRVVQESADGTVKYLFELPDGMLIETVLMRQHYGHSVCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMLVQKYFDDRKQGERVSHVVVMGIGEPFDNYKNVMCFLRVINDDNGLAIGARHITVSTSGLAHKIRDFANEGVQVNLAVSLHAPNNDLRSSIMRVNRSFPLEKLFSAIEYYIEKTNRRVTFEYIMLNEVNDSIKQAQELADLTKTIRKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDVLKKNGVNCVVRQEHGTDIDAACGQLRSKTMKKDREKVTATK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADA_YERPA
Sequence: MSEIFDVNAAIYPFPARPVPLDTNEKAFYREKIKTLLKQRDAVLVAHYYTDPEIQALAEETGGCVADSLEMARFGNNHPASTLLVAGVRFMGETAKILNPEKKVLMPTLNAECSLDLGCPVDEFTAFCDSHPDRTVVVYANTSAAVKAKADWVVTSSIAVELIEHLDSLGEKIIWAPDRHLGSYVQKKSGADVLCWQGACIVHDEFKTQALARMKALYPDAAVLVHPESPQAVVDMADAVGSTSQLIQAAKTLPQKTLIVATDRGIFYKMQQACPDKELFEAPTAGEGATCRSCAHCPWMAMNGLRAIAEGLEQGGVMHEIHVDEELRQQALIPLNRMLDFANQLKLQVKGNA
What is the function of this protein?
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
What are the official names of this protein?
Quinolinate synthase.
What is the protein family that this protein belongs to?
Belongs to the quinolinate synthase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BGLA_ASPTN
Sequence: MKLSILEAAALTAASVVSAQDDLAYSPPYYPSPWADGHGEWSNAYKRAVDIVSQMTLTEKVNLTTGTGWELERCVGQTGSVPRLGIPSLCLQDSPLGIRMSDYNSAFPAGINVAATWDKKLAYQRGKAMGEEFSDKGIDVQLGPAAGPLGRSPDGGRNWEGFSPDPALTGVLFAETIKGIQDAGVIATAKHYILNEQEHFRQVGEAQGYGFNITETVSSNVDDKTMHELYLWPFADAVRAGVGAVMCSYNQINNSYGCQNSLTLNKLLKAELGFQGFVMSDWSAHHSGVGAALAGLDMSMPGDISFDSGTSFYGTNLTVGVLNGTIPQWRVDDMAVRIMAAYYKVGRDRLWTPPNFSSWTRDEYGFAHFFPSEGAYERVNEFVNVQRDHAQVIRRIGADSVVLLKNDGALPLTGQEKTVGILGEDAGSNPKGANGCSDRGCDKGTLAMAWGSGTANFPYLVTPEQAIQNEVLKGRGNVFAVTDNYDTQQIAAVASQSTVSLVFVNADAGEGFLNVDGNMGDRKNLTLWQNGEEVIKTVTEHCNNTVVVIHSVGPVLIDEWYAHPNVTGILWAGLPGQESGNAIADVLYGRVNPGGKTPFTWGKTRASYGDYLLTEPNNGNGAPQDNFNEGVFIDYRRFDKYNETPIYEFGHGLSYTTFELSGLQVQLINGSSYVPTTGQTSAAQAFGKVEDASSYLYPEGLKRISKFIYPWLNSTDLKASTGDPEYGEPNFEYIPEGATDGSPQPRLPASGGPGGNPGLYEDLFQVSVTITNTGKVAGDEVPQLYVSLGGPNEPKRVLRKFERLHIAPGQQKVWTTTLNRRDLANWDVVAQDWKITPYAKTIFVGTSSRKLPLAGRLPRVQ
What is the function of this protein?
Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass.  Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).
What are the official names of this protein?
Probable beta-glucosidase A, Beta-D-glucoside glucohydrolase A, Cellobiase A, Gentiobiase A.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 3 family.
What are the subcellular locations of this protein?
Secreted.
Protein: VPS3_ARATH
Sequence: MSKSRAVVELTARFDLGGDDKIRALSLSPISDSQTLVYLGTYSGSLILLSLDTLTNTVSRLASVSLSPSPVESIFVLGEERGRVLALCNGYLFLLDSLLSQPAKRLGGLLKGINVIAKRVRGRDSSSTDLLPSEISTDSSSSKKFLQLLGAGNLVSDVRGNDSRHERVQQGHYVFAVAIGERMLLIELQCAEKEGLSGSFVVLKEILGIGGIKTLVWLDDYVIAGTVKGYSLISCVTGLSGVIFTLPDVSGPPLLKLLCKEWKVLLLVDNVGVVVDTNGQPIGGSLVFRRRPDSVGELSFYLVTVGDGKMEIHQKKSGACVQSVSFGPQGCGPSLLAADEAGDGNLLVVTTLSKLIFYRRVPYEEQIKDLLRKKRYRETISLVEELDSQGEISKDMLSFLHAQIGYLLLFDLRFEEAVNQFLKSEKMEPSEVFPFIMRDPNRWSLVVPRNRYWGLHPPPAPFEDVVDNGLMAIQRANFLRKAGMDTPVDEEFFSDPPSRADLLDSAIKNITRYLEISREKGLTLPVREGIDTLLMLLYRALNRVEDMENLASSGNNCVVEELETLLTESGHLRTLAFLYATKGMGAKALAIWRLFTKNYSSGLWQDSDDLVPYLHDNELIRLSGKEAAAAEAARILEEPCDPELALQHLSWIADVNPLFAIQVLTSDKRTEELSPEQVIQAIDPKKVEIIQRYFQWLIEERDYTDPQLHTSYALSLARSALECVEVQNGIQEADVPNGSEAHDSNVGSISLFEVDVRERLQAFLQSSDLYDPEEILELVEGSELWLEKAILYRRIGKETLVLQILALKLEDCAAAEQYCVEIGRPDAFMQLLDMYLDPQNGKEPMFKAAVRLLHNHGESLDPLQVLDKLSPDMPLKLASDTILRMLRARVHHHRQGQIVHNISRALDVDSRLARLEERSRHMQINDESLCDSCYARLGTKLFAMYPDDTIVCYKCYRRLGESKSVTGRDFKRDVLIKPGWLVNR
What is the function of this protein?
Essential protein required during embryogenesis.  Believed to act as a component of the putative class C core vacuole/endosome tethering (CORVET) endosomal tethering complexes.  CORVET is required for vacuolar transport of SYP22.  Involved in root development (PubMed:29463724).  Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway (By similarity).
What are the official names of this protein?
Vacuolar sorting protein 3.
What is the protein family that this protein belongs to?
Belongs to the TRAP1 family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Co-localizes with VAMP727, VPS18, RABG3F and RABF2B at cytoplasmic punctate structures.
Protein: LEXA_ALCBS
Sequence: MSSKLTDRQQQVLDCIRECLKDNGMAPTRAEIADIMGFQSKNAASDHLRALERKGYIKLHSDRSRGIQLLDHAYWGEEELPVVGKVAAGIPIEAIENVERTVPVPQGLFKQRPTYLLKVQGDSMVDAGIFDGDLIAVRKSNVARSGEIVVARIDEEVTVKTLKLNKSSATLLPANEAYEPIKVPADQLIIEGIFVGLIRDPNSF
What is the function of this protein?
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA.  In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
What are the official names of this protein?
LexA repressor.
What is the protein family that this protein belongs to?
Belongs to the peptidase S24 family.
Protein: SYK_BACMK
Sequence: MDNMNHEELNDQLLVRREKLHNLREQGIDPFGKRFERTNSTTDLVSLYGEFSKEELEEKEITVSIAGRIMTKRGKGKAGFAHIQDLQGQVQIYVRKDTVGDEEYELFTTADLGDLVGIEGKVFKTNVGELSVKAIGFTLLTKSLRPLPDKYHGLKDVEQRYRQRYLDLITSMESRETFVTRSKIIREMRRYLDDNGYLEVETPMMHAIAGGASARPFTTHHNALDMELYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYNDIMKLTENMVAHIAKKVLGTTTIQYGDYEINLEPEWTRLHMVDAIKQHSGADFWNPMSVEEARELAKEHNVEIKNTMEVGHIINEFFEQKVEDKLIQPTFIYGHPVEISPLAKKNDEDPRFTDRFELFIVAREHANAFTELNDPIDQKERFEAQLKEREQGNDEAHMMDDDYIEALEYGMPPTGGLGIGIDRLVMLLTNAPSIRDVLLFPAMRHKQD
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LRAT1_BOVIN
Sequence: MGNQLDRITHLNYSELPTGDPSGIEKDELRVGVAYFFSDEEEDLDERGQPDKFGVKAPPGCAPCPESPSRHHHHHHHHHLLHQLVLNETQFSAFRGQECIFSKVSGGPQGADLSVYAVTALPALCEPGDLLELLWLQPAPEPPAPAPHWAVYVGGGQIIHLCQGEIRQDSLYEAGAANVGRVVNSWYRYRPLVAELVVQNACGHLGLKSEEICWTNSESFAAWCRFGKREFKAGGEVPAGTQPPQQQYYLKVHLADNKVHTARFHSLEDLIREKRRIDASGRLRVLQELADLVDDKE
What is the function of this protein?
May play a role in cell morphology and motility.
What are the official names of this protein?
Protein LRATD1, LRAT domain-containing 1, Protein FAM84A.
What is the protein family that this protein belongs to?
Belongs to the LRATD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS20_ALKCK
Sequence: MPNIKSAIKRVKTNEKRRAQNAAQKSALRTAVKHFETAAANGDVEKAQAAFVEASKKLDKAATKGLIHKNAASRQKSRLAKKLNGLSA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
Protein: IHFA_VIBPA
Sequence: MALTKAELAENLFDKLGFSKRDAKETVEVFFEEIRKALESGEQVKLSGFGNFDLRDKNERPGRNPKTGEDIPITARRVVTFRPGQKLKARVENLKKEQ
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: TXP1_PARSR
Sequence: YCQKWMWTCDSARKCCEGLVCRLWCKKII
What is the function of this protein?
Potent and specific blocker of Kv4. 2/KCND2 (IC(50)=5 nM) and Kv4. 3/KCND3 (IC(50)=28 nM) potassium channels (PubMed:10051143).  Acts by altering the gating properties of these channels (PubMed:10051143).  Also shows moderate inhibition on human voltage-gated sodium channel Nav1. 7/SCN9A activation (IC(50)=423 nM) (PubMed:25026046).
What are the official names of this protein?
Kappa-theraphotoxin-Ps1a, Kappa-TRTX-Ps1a, PaTx1, Phrixotoxin-1.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 30 (phrixotoxin) family.
What are the subcellular locations of this protein?
Secreted.
Protein: HIS2_CAUVN
Sequence: MSQRLTDVLQRLAATIEARKGGDPSVSYTAKLLNDPALAAKKLGEEAVETVIAAVAQGSDALAAESADLLYHWLALMAASGVSLDAVAEKLEAREGTSGIAEKASRA
What are the official names of this protein?
Phosphoribosyl-ATP pyrophosphatase, PRA-PH.
What is the protein family that this protein belongs to?
Belongs to the PRA-PH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: D107A_PANTR
Sequence: MPGAMKIFFFIFAALILLAQIFQARTAIHRALISKRMEGHCEAECLTFEVKTGGCRAELAPFCCKNRKKH
What is the function of this protein?
Has antibacterial activity.
What are the official names of this protein?
Beta-defensin 107A, Beta-defensin 7, BD-7, DEFB-7, cBD-7, Defensin, beta 107, Defensin, beta 107A.
What is the protein family that this protein belongs to?
Belongs to the beta-defensin family.
What are the subcellular locations of this protein?
Secreted.
Protein: IHOG_DROPE
Sequence: MSPLTSSLLLFSLLTSSLEAIPVLQPSFPPSSPSPAPSPGVRILRAPESIVAPLGDEVVFECETSLQPEGFEWSYRRWPNAANSNGSVGASRFKYLKSGNGKLNVTQETAISRLRVLVRPDTVGEYRCIGWFGPLVVTSTTARLELANTSVKGRQETHLQWRVAPGNSVLWSCGQQVHSNPSASWSYYRNGVEIKPELAATNGNLFLTNVSTASAGKYTCLATNPASGARIEISSSMVLEVLSGRGSQNKAPHLLSGQPTSQAVTIREGSTLLLLCPGVGSPTPTAVWSSPDVVEAIHNKRTRVLNHGLEISNVQGHDTGTYICYLDNGVRPTLEHFINVTVEVPPRITRPPWADLTNEGERMQLECEATGVPAPELYWLLNGESSINDTEAEQLPNGYLVLHSVQKRHAGYVQCFARNRLGEQSAGTLLQVNPKQIQSEPRETGSGGGFGSHRSMKPVNHGQKPTKMIPPSPPNVTRLSDESVMLRWHVPRNDGLLILFFKVQYRMISEGKRKNWQTTNDNIPYGKPKWNSELGKSFTASVTDLKPQRTYRFRILAVYSNNDNKESNTSAKFYLQPGAALEPMPVPELLEIEEYSETAVVLHWRLDSDADEHLITGYYAYYRPSSSAGEYYKATIEGAHARSFQIATLEAATIYEFKLQSFSAVSASEFSALKQGRTQRPRASTTEEPTIQGIGDRDTTSHNQPSHNETVSMSPMLTGTIGGGALLLILLVSAFLCMCRRRSPRGRGQTQNKPRMAELREDFVPLGSCSPNKQRQRTRHIHITLNPLAQQQQQQLDEKNPPGLETDNDMAYFQRQPTYEYDPGLRRMSSSSLRRSQRTLERAGGANSGGNNGGNNNNLNQSSEAGTADGPCMQSSSKPGRVIMKRPRLSSRSENLSSGSLNSVGV
What is the function of this protein?
Mediates response to the active Hedgehog (Hh) protein signal in embryos, functioning upstream or at the level of patched (ptc).
What are the official names of this protein?
Interference hedgehog.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. IHOG family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: REX_STAHJ
Sequence: MAHNKSKIPRATLKRLPLYYRFVNTLKSKGIDRVNSKAISEALNIESATIRRDFSYFGELGKKGYGYNIDSLLEFFKTALSDSDNIHIALVGVGNLGRALLTYNFSIHDEMTITEAFDIDEQIVGTEIGDVSVHHMNDLKKVLNAQNINVVILTTPEEAAQRVANQLVEADIQGILNFTPARIEVPNTVQVHHIDLGIELQSLLFFMKNYSN
What is the function of this protein?
Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
What are the official names of this protein?
Redox-sensing transcriptional repressor Rex.
What is the protein family that this protein belongs to?
Belongs to the transcriptional regulatory Rex family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FDFT2_ARATH
Sequence: MGSLSTILRHPDELYPLLKLKLAITKAQKQIPLEPHLAFCYSILHKVSKSFSLVIQQLGTELRNAVCVFYLILRALDTVEDDTSVPVEIKVPILIAFHRHIYDGDWHFSCGTKEYKLLMDQFHHVSAAFLKLEKGYQEAIEDITKRMGAGMAKFICKEVETIDDYDEYCHYAAGLVGLGLSKIFIASELEILTPDWKQISNSTGLFLQKTNIIKDYLEDINERPKSRMFWPREIWGKYVDKLEDFKNEEKATKAVQCLNEMVTNALNHVEDCLKSLASLRDPAIFQSCAIPQIVAIGTLALCYNNVQVFRGVVRLRRGLIAKVIDRTKTMDDVYGAFYDFSCMLQTKVDNNDPNAMKTLNRLETIKKFCKENGGLHKRKSYVNDETQSKAIFVVMFVLLLAIVVVYLKANQCK
What are the official names of this protein?
Inactive squalene synthase 2.
What is the protein family that this protein belongs to?
Belongs to the phytoene/squalene synthase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LGB3_VICFA
Sequence: MGFTQQQEALVNSSWESFKQNPSYSVLFYTIILEKAPAAKGMFSFLKDSAGVVDSPKLQAHAEQVFGMVRDSAIQLQATGEVVLKNGSLGAIHIQKGVVDPHFVVVKEALLKTIKEASGDKWSEELSIAWEVAYDGLATAIKKAMS
What is the function of this protein?
Provides oxygen to the bacteroids.  This role is essential for symbiotic nitrogen fixation.
What are the official names of this protein?
Leghemoglobin 49, VfLb49.
What is the protein family that this protein belongs to?
Belongs to the plant globin family.
Protein: FOLD_METB6
Sequence: MVTILDGKAVSEKRLELLKETISESGLYPRLATVIVGSDPASQMYVRMKHRACERVGIGSVGIEIPGDATTQNVLESVTRLNRDTDINGILIQLPLPKRVDTERVIAAVNTEKDVDGFHPTSLGLLMSGRPRFAPCTPKGIMNLLAEYHITVAGARAVVAGRSIDVGRPMAALLTNADATVTICHSRTRDLPAELRQADILVSAVGKAHFITPEMVKPGAVVIDVGINQLNGKLVGDVDFEAVKEVASAITPVPGGVGPMTIATLMENTFAAAAMRMP
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: TPIS_BACCE
Sequence: MRKPIIAGNWKMNKTLSEAVSFVEEVKGQIPAASAVDAVVCSPALFLERLVAATEGTDLQVGAQNMHFEKNGAFTGEISPVALSDLKVGYVVLGHSERREMFAETDESVNKKTIAAFEHGLTPIVCCGETLEERESGKTFDLVAGQVTKALAGLTEEQVKATVIAYEPIWAIGTGKSSSSADANEVCAHIRKVVAEAVSPEAAEAVRIQYGGSVKPENIKEYMAQSDIDGALVGGASLEPASFLGLLGAVK
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).
What are the official names of this protein?
Triosephosphate isomerase, TIM, TPI, Triose-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the triosephosphate isomerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_CORU7
Sequence: MISSLRGDVIDKGLDYVVIECGGVGYRCLATGDTLATLRRGESAFVLTSLVIRDDAHTLYAFSTSEQRETFGILQKVSGVGARLAMGVMSVLQPADIARAVEEGDIKTLQQAPGVGKRLAERMAVDLKGKFPALEATSGQATIGDIAATGNDTALQSQVVEALVGLGFTEAKAATAVKKILEEQNGTTDPSSVLREALQRLSGQKR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: LEUD_ECO7I
Sequence: MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIASYEEKQPAFMR
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TPS1A_ASPNG
Sequence: MPSLENPTFQNEARLLLVSNRLPITIKRSDDGRYDFSMSSGGLVSGLSGLSKSTTFQWYGWPGLEVPEEEIPVVKERLKQEYNAVPVFIDDELADRHYNGFSNSILWPLFHYHPGEITFDESAWEAYKEANRLFAKAVAKEVQDGDLIWVHDYHLMLLPEMLREEIGDSKENVKIGFFLHTPFPSSEIYRILPVRNELLLGVLHCDLIGFHTYDYTRHFLSACSRLLGLTTTPNGIEFQGKIIACGAFPIGIDPEKFEEGLKKEKVQKRIAMLEQKFQGVKLMVGVDRLDYIKGVPQKLHALEVFLSDHPEWVGKVVLVQVAVPSRQDVEEYQNLRAVVNELVGRINGKFGTVEFMPIHFLHKSVNFDELIALYAVSDACIVSSTRDGMNLVAYEYIATQKKRHGVLVLSEFAGAAQSLNGSIIINPWNTEELAGAYQEAVTMSDEQRALNFSKLDKYVNKYTSAFWGQSFVTELTRISEHSAEKFHAKKASFSDNNSENGEPSNGVETPAQEQVAQ
What is the function of this protein?
Synthase catalytic subunit of the trehalose synthase complex that catalyzes the production of trehalose from glucose-6-phosphate and UDP-alpha-D-glucose in a two step process.
What are the official names of this protein?
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 1, Trehalose-6-phosphate synthase, UDP-glucose-glucosephosphate glucosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 20 family.
Protein: ARGC_PECAS
Sequence: MLNTLIVGASGYTGAELALYLNRHPQMNITALMVSAQSVDAGKLISDLHPQLKGIIDIPVKPLTDAEEAAKGVDVVFLATDHKVSHDLAPIFLAAGCTVFDLSGAFRVQDAEFYRRYYGFEHQHTDWLAKAVYGLAEWRAESVKQAQLIAVPGCYPTAAQLALKPLLDAQLLNSAQWPVINAVSGVSGAGRKASLTSSFCEVSLQPYGIFNHRHEPEISTHLGTPVIFTPHLGNFARGILETITCRLQPGVTQQDVAEAYHNAYHDKPLVRLYDKGVPALKSVVGLPFCDIGFAVDGEHLIVVATEDNLLKGAAAQAVQCMNIRFGFPETQSLI
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL6_THEON
Sequence: MPIDAWVREEVEIPEGVEVTIERNVVKVRGPKGELERELKYPGVQIFTEDGKVVIYKEFPRKKDIAIARTFKAHIANMIKGVTEGFTYKLKVVYSHFPMTVKVQGDEVVIENFLGEKNPRRAKILPGVTVKVMGSEVIVEGIDKEAVGQTAANIEQATRITKWDRRVFQDGIYIVEKAGKPIKF
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: SFGH1_ECOSM
Sequence: MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAGNEKLPVLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIHNELPDLVMQHFPATTRKSISGHSMGGLGALVLALRNPDEYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKEAWLDYDPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNMR
What is the function of this protein?
Serine hydrolase involved in the detoxification of formaldehyde.  Hydrolyzes S-formylglutathione to glutathione and formate (By similarity).
What are the official names of this protein?
S-formylglutathione hydrolase FrmB, FGH.
What is the protein family that this protein belongs to?
Belongs to the esterase D family.
Protein: COQ4_PLAKH
Sequence: MYNFVKIFRSNFIDINAANKLEIFLKTILRIYKTPARTHLLAHAADISAIYAVREIYNYMKNDEEGRIILKEKPLLIRQDIQFNELKKLPKNTLGYKYMEFLETYKLHAHDREVSHFFTDLNYSYILTRYRQIHDIGHVVYNLNISIESEAALKVIELVQTKLPITALAILIAPLMTPLYRFQYIFKDSIPSNFLTPNFDYTYNDAYNYVDELSIKQYEYNLTDYFHVDKRDDQKFYSKMYQYYLDNINNSSAVRGSIIYGFENKSNNDIIYDHPNREYIFLKNLKKKHLLFQYKPRKNLLRELYPWAYMAGVSTTKPLHSIHIEKWLDKDIDLFRRTYNISPLPDHLNLMAGIN
What is the function of this protein?
Component of the coenzyme Q biosynthetic pathway.  May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis.  Required for steady-state levels of other COQ polypeptides.
What are the official names of this protein?
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial, Coenzyme Q biosynthesis protein 4 homolog.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: YCIY_ECOUT
Sequence: MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILNKQRNSLLFAIYNI
What are the official names of this protein?
Uncharacterized protein YciY.
What is the protein family that this protein belongs to?
Belongs to the YciY family.