PharMolix/UniProtQA huggingface dataset:
Protein: INDY1_DROME
Sequence: MATETTKMIYTPPPLDIKMEIEIGEQPQPPVKCSNFFANHWKGLVVFLVPLLCLPVMLLNEGAEFRCMYLLLVMAIFWVTEALPLYVTSMIPIVAFPIMGIMSSDQTCRLYFKDTLVMFMGGIMVALAVEYCNLHKRLALRVIQIVGCSPRRLHFGLIMVTMFLSMWISNAACTAMMCPIIQAVLEELQAQGVCKINHEPQYQIVGGNKKNNEDEPPYPTKITLCYYLGIAYASSLGGCGTIIGTATNLTFKGIYEARFKNSTEQMDFPTFMFYSVPSMLVYTLLTFVFLQWHFMGLWRPKSKEAQEVQRGREGADVAKKVIDQRYKDLGPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLLNSKDIRNSMPTIFVVVMCFMLPANYAFLRYCTRRGGPVPTGPTPSLITWKFIQTKVPWGLVFLLGGGFALAEGSKQSGMAKLIGNALIGLKVLPNSVLLLVVILVAVFLTAFSSNVAIANIIIPVLAEMSLAIEIHPLYLILPAGLACSMAFHLPVSTPPNALVAGYANIRTKDMAIAGIGPTIITIITLFVFCQTWGLVVYPNLNSFPEWAQIYAAAALGNKTH
What is the function of this protein?
Cation-independent electroneutral transporter (not associated with membrane depolarization) of a variety of tricarboxylic and dicarboxylic acid-cycle intermediates.  There is also small, but detectable, transport of monocarboxylics.  Transport is through the epithelium of the gut and across the plasma membranes of organs involved in intermediary metabolism and storage.  Affinity for substrates is citrate > succinate > pyruvate.  Fumarate, a-ketoglutarate, and glutarate are also transported, but not lactate.  Transport mechanism that is not coupled to Na(+), K(+), or Cl(-).  Function is shown in Xenopus oocytes and human retinal pigment epithelial (HRPE) cell lines.
What are the official names of this protein?
Protein I'm not dead yet, INDY transporter protein, drIndy.
What is the protein family that this protein belongs to?
Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
What are the subcellular locations of this protein?
Basolateral cell membrane; Multi-pass membrane protein. Note=Basolateral membrane of cells in the midgut.
Protein: UBC_PIG
Sequence: MQIFVKTLTGKTITLEVEPSDTIENVKGKIQEKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGF
What is the function of this protein?
Exists either covalently attached to another protein, or free (unanchored).  When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains).  Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B.  Linear polymer chains formed via attachment by the initiator Met lead to cell signaling.  Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed.  When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity).
What are the official names of this protein?
Polyubiquitin-C.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin family.
What are the subcellular locations of this protein?
[Ubiquitin]: Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein.
Protein: PCL7_YEAST
Sequence: MELSSPSKKTTTSPINIPGGNRDNLIIGPHSHSFKTDPFSSNNSSLLSKISTNPSLESPFSSKSLLDCSPVQAVKKSLESEAKTHSLDEETNEQTDVKILNIADFPTDELILMISALLNRIITANDETTDVSQQVSDETEDELLTPILAFYGKNVPEIAVVQYLERIQKYCPTTNDIFLSLLVYFDRISKNYGHSSERNGCAKQLFVMDSGNIHRLLITGVTICTKFLSDFFYSNSRYAKVGGISLQELNHLELQFLILCDFKLLVSVEEMQKYANLLYKFWNDQ
What is the function of this protein?
Cyclin partner of the cyclin-dependent kinase (CDK) PHO85.  Together with cyclin PCL6, controls glycogen phosphorylase and glycogen synthase activities in response to nutrient availablility.  The PCL7-PHO85 cyclin-CDK holoenzyme has GLC8 kinase activity and phosphorylates and inactivates the phosphatase PP1-2 inhibitor GLC8, causing activation of PP1-2, which then dephosphorylates and activates glycogen phosphorylase.  PCL7-PHO85 also phosphorylates MMR1 and YJL084C.
What are the official names of this protein?
PHO85 cyclin-7, PHO85-associated protein 1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family. PHO80 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPRA_MYCSJ
Sequence: MPVRILVVDDDRAVRESLRRSLSFNGYSVELAQDGVEALDLIANNRPDAVVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTSPDEGPDSPALTFLDLTLDPVTREVTRGSRQISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYIGYLRRKTEASGEPRLIHTVRGVGYVLRETPP
What is the function of this protein?
Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host.  Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity).
What are the official names of this protein?
Response regulator MprA, Mycobacterial persistence regulator A.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIMO_RHOPS
Sequence: MQQAAAPKISFVSLGCPKALVDSERIITRLRAEGYELARQHDGADLVIVNTCGFLDSAKQESLAAIGEAMAANGKVIVTGCMGAEPEQIEAAYPGVLSITGPQQYESVLEAVHRAKPALHNPHLDLVPEQGIRLTPRHYAYLKISEGCNNRCSFCIIPKLRGDLVSRSADDVLREAEKLVAAGVKELLVISQDTSAYGVDLKYAESPWKDRTVRAKFIDLARELGELGAWVRLHYVYPYPHVDEVIGLMAEGKVLPYLDIPFQHASPDVLKLMKRPAAQDKTLDRIKRWRADCPDLALRSTFIVGFPGETERDFEFLLDWLDEAEIDRLGAFKYEPVAGAPSNALPDQISAEVKQERWNRLMARQQVISARRLKRKVGTRQQIIIDEVGPTVAKGRSKADAPEIDGSVYLSSRRPLRVGEIVTAKIDRADAYDLHGTVAGF
What is the function of this protein?
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
What are the official names of this protein?
Ribosomal protein S12 methylthiotransferase RimO, S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. RimO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSHD_THECD
Sequence: MDERALVFSDGLTDPQISQVLALAEAATRHDGVAPLSEQALLTLRAGRSRSLLSLEDGVIAGYAHLDPAPDGAGASGEVVVHPGRRRRGHGRALLRALRERARGPLRVWAHGDLAPAAALAAAEGMARVRVLLQMRRPLQDSPLPEVTVPDGVTIRTFEPGRDETAWLRVNGRAFADHPEQGAWTLEDLRARQAEPWFDPAGLFLAERDGRLIGFHWTKVHPDPIGEVYVVGVDPSAQGLGLGRVLTLIGLHHLRDRGLPAVMLYVDESNRPALRLYESLGFTRYAVDVMYQSPPPH
What is the function of this protein?
Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
What are the official names of this protein?
Mycothiol acetyltransferase, MSH acetyltransferase, Mycothiol synthase.
What is the protein family that this protein belongs to?
Belongs to the acetyltransferase family. MshD subfamily.
Protein: STX2_RAT
Sequence: MRDRLPDLTACRKSDDGDNAVIITVEKDHFMDAFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANRIRGKLKAIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGRTTTDEELEEMLESGKPSIFISDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVVVAVIAVLALIIGLTVGK
What is the function of this protein?
Essential for epithelial morphogenesis.  May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
What are the official names of this protein?
Syntaxin-2, Epimorphin.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Membrane; Single-pass type IV membrane protein.
Protein: CTR2_PIG
Sequence: MIPCRATLSFARCLIRRKVVTLDSLEDSKLCRCLSTMDLIALGVGSTLGAGVYVLAGEVAKADSGPSIVVSFLIAALASVMAGLCYAEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTLDELLNKQIGQFFRTYFKMNYTGLAEYPDFSAVCLILLLAGLLSFGVKESAWVNKVFTAVNILVLLFVMVAGFVKGNVANRKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATCFYAFVGFDCIATTGEEVRNPQKAIPIGIVTSLLVCFMAYFGVSAALTLMMPYYVLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLLGSMFPLPRILFAMARDGLLFRFLARVSKRQSPVAATLTAGVISAVMAFLFDLKALVDMMSIGTLLAYSLVAACVLILRYQPGLSYEQPKYCPEKEALGSCASAASKSKSQVTVLPEWGFSLRAFFSPSLLPTKQSASLVSFLVGFLAFLILGLSILTTYGVHAIARLEAWSLALLVLFLVLCVAVVLTIWRQPQNQQKVAFMVPFLPFLPAFSILVNIYLMVQLSADTWIRFSIWMALGFLIYFAYGIRHSLEGNSRDEDEDEDTHSNNVHTAAEEKSAIQANDHHQRHLSLPFIFHEKTSEC
What is the function of this protein?
Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine).  May play a role in classical or alternative activation of macrophages via its role in arginine transport.
What are the official names of this protein?
Cationic amino acid transporter 2, CAT-2, CAT2, Low affinity cationic amino acid transporter 2, Solute carrier family 7 member 2.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SPEF1_BOVIN
Sequence: MAGSVDEEALHQLYLWVDNIPLSRPKRNLSRDFSDGVLVAEVIKFYFPKMVEMHNYVPANSLQQKLSNWSHLNRKVLNKLNFSVPEDVMRKIAQCAPGVVELVLIPLRQRLEERQRRRKQGIGSLQELAPQDGTDYMDVGLSQKARGEGVPDPQGRGQLREGRLPVPRPPGDSQALQSDPSFILQIAEKEQELLASQETVQVLQMKVRRLEHLLQLKNVRIEDLSRRLQQAERKQR
What is the function of this protein?
Microtubule-associated protein involved in the stabilization of microtubules along the axis of migration during radial intercalation.  Promotes the establishment and stabilization of an axis of microtubules required for the active migration of cells into the outer epithelium (By similarity).  Microtubule-associated protein that promotes microtubule bundling and stabilizes microtubules against depolymerization in response to cold shock (By similarity).  Essential for ciliary central apparatus formation which requires both its microtubule-binding and bundling activities and for ciliary localization of HYDIN and SPAG6 in ependymal cilia (By similarity).  Binds actin in intestinal epithelial cells (IECs), essential for IECs survival and contributes to formation of filopodia and lamellipodia in migrating IECs (By similarity).  Regulates planar cell polarity signaling pathway and asymmetric microtubule accumulation in ciliated epithelia (By similarity).
What are the official names of this protein?
Sperm flagellar protein 1.
What are the subcellular locations of this protein?
Cytoplasm. Cell projection, cilium, flagellum. Cytoplasm, cytoskeleton, cilium axoneme. Apical cell membrane. Basolateral cell membrane. Cytoplasm, cytoskeleton, stress fiber. Cell projection, microvillus. Cell projection, lamellipodium. Cell projection, filopodium. Note=Present in the tails of developing and epididymal sperm, internal to the fibrous sheath and around the outer dense fibers of the sperm flagellum. Also found at the apical tip of cilia. Colocalizes with TJP1 and CGN at sites of cell- cell contact in intestinal epithelial cells (By similarity).
Protein: UBID_PSEA7
Sequence: MTFKDLRDFIAQLEQRGALKRIQVPISPVLEMTEVCDRTLRAKGPALLFEKPTGFDMPVLGNLFGTPERVALGMGAEDVGALREIGTLLAQLKEPEPPKGFKDAWAKLPMYRKVLSMAPKVLKDAPCQEVVEEGDDVDLGRLPVQTCWPGDVGPLITWGLTVTRGPNKERQNLGIYRQQVIGRNKVIMRWLSHRGGALDYREWCQKHPGQPYPVAVALGADPATILGAVTPVPDTLSEYAFAGLLRGHRTELVKCRGSDLQVPASAEIVLEGVIHPGEMADEGPYGDHTGYYNEVDRFPVFTVERVTRRQKPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDIDARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPVSGLGSKMGLDATHKWPGETSREWGRAIVKDEAVTRRIDELWSSLGID
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CCA1_CANGA
Sequence: MFKAIRRVFTMIPRIQLTEKETRICNLLKDYTAHYNSLHYGQEPLTLRITGGWVRDKLLGQGSHDLDIAINIMSGEEFATGLNGYLLEHFDKYGVKPHSIHKIDKNPEKSKHLETATTKLFDVEVDFVNLRSEEYTEDSRIPTTQFGTPEEDALRRDATLNALFYNIQQDAVEDFTKRGWQDLQDGVLRTPLPARQTFLDDPLRVLRLIRFASRFNFNIEAGVLKEMHDPEINEAFNNKISRERIGVEMEKILVGPNPILGLKLIQRTHLENVIFLWHGDQSVIEYNRKNWPQTKDVEDIYKKGIFNHHLKNFIHHYKDFLSRYLKLRQAIETKDKSFQQNFLLASILIPMADLKIIALPKKKLNNTLPVSESIVREGLKFNKASSIVVARCVENIAAYNSMVEKYLQSGDLKRSEVGTFLRELRGDWEIVHYVSLMDQYLKYISRKDNVVNIIDKYDRFWNYIQEQNLQDSDKMVPIIDGKRMVKILETKPGPWLGKINDEVILWQFDHPQGTEQELISFIKSILPNYLQ
What is the function of this protein?
This enzyme carries out synthesis of the tRNA CCA terminus without the direction of a template using the multiple accepting and donating subsites within its active site.
What are the official names of this protein?
CCA tRNA nucleotidyltransferase, mitochondrial, CCA-adding enzyme, tRNA CCA-pyrophosphorylase, tRNA adenylyltransferase, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
What are the subcellular locations of this protein?
Mitochondrion. Cytoplasm. Nucleus.
Protein: MOBA_CERSP
Sequence: MRLFGLILAGGEGRRMGGTDKASLTLGGRPLVTWVAERLGPQVEELAISANGDPARFAGLGLPVLRDEHPQGPLSGVLAGLRWAAAAGADALVTAPVDTPFVPGDLAPRLWLAGEGACAVAEAGGRVHPACGLWPVAVAEDLAAWLAAGEARVMGFAARHGAARAGFPDENAFLNLNAPEDLARAESLLRKDA
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_METST
Sequence: MPVINFTYEELFEQLGEELPKDELINILPMISSDVESYDDVEVKAEFFPNRPDYYSVEGIVRSLKGYLELEKGIPEYDVKKTDTTITVDSELENIRPYVACCMIKNVKIDDNQLRNIMEFQEHLHWVIGRDRKKVAIGIHDLDKVEGPFYYKAGNPNETSFIPLESRENLTLNEILENHEKGEKYAKLLKEFDKYPLIVDGNGNIMSMPPIINSELTKLTTKTTNLFIDVTGTDINAVTNALNIIAANLSENGATIETIEVNYPYHDNKTYPDFEPKIIDVHTKTAQEYIGIDLTADKIVETLEKTRFNATKINEETVRVTVPRYRIDILHEVDIIENIALGYGFNELPAQLPDFATVANPDSKRQFDQILEQVMIGLSFTEIKSLMLTSETQHYTKLRKEVEEDRVTVAQPITQDRTMIRKSLINSLLEFLEDNKHEELPQKIFEIGDVAYINENAETKMVTVKKLAAAQISSVANFTTIKSIVESFVANMGFEMELEDHDDSAFIKGRCAKFTTKPLNKNTPFTFKGYFGEIHPEVLTNFELEYPVIAFEVEFSEVE
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPX_SYNPW
Sequence: MAKFDAHLKCSFCGKSQEQVRKLIAGPGVYICDECIDLCNEILDEELIDSQGGSRQGAEPSRKAGAAQARKSTKPAPTLASIPKPQDIKAFLDQQVVGQEAAKKVMSVAVYNHYKRLAWQGDGKGETEETATRLHKSNILLIGPTGCGKTLLAQTLAEMLDVPFAVADATTLTEAGYVGEDVENILLRLLQKADMDVDLAQRGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKMLEGTVANVPPQGGRKHPYQDCIQIDTSQILFICGGAFVGLDDVVQKRMGRNAIGFMPTEGRGRGKATRDLQAAQVLRHLEPDDLVRYGLIPEFIGRMPVSAVLEPLDEHALESILTEPRDALVKQFRTLLSMDNVQLEFEPSAIEAIAQEAHRRKTGARALRGIVEELMLDLMYELPSRKDASSFTITRAMVEEHTGGKVLPLPGSERQQESA
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: THIG_MARMS
Sequence: MSSLFIAGHEFHSRLFTGTGKYASADAMMDSLTASESELVTLSLRRMDLKNQTDNILKPLQQQRIKLLPNTSGARTAKEAVFAAELAREALETNWVKLEIHPDPRYLMPDGMETLLAAEELIKKGFVVMPYVHADPVLCKRLEEVGCQCVMPLGSPIGSNMGLASRPFLEIIIEQSTVPVIIDAGIGAPSDAALALEIGADAVLVNTAMAVARQPAKMGKAFRLAVEAGRMAYESGLGERRVQAQATSPLTDFLGALS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNP2_METAC
Sequence: MKRLLPSLRTKKRYLAFELISEEPAGRGDIVKEVISSASSLLGDITTSDCDIRVLGFEAGKGIIQCSHTRVKETRAALATLTRVNGKRATLHVLGASGTVKKATEKFLKDYTVFEPEIHEKRDSRKTPGKVD
What is the function of this protein?
Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.
What are the official names of this protein?
Ribonuclease P protein component 2, RNase P component 2, Pop5.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LEU1_ALIB4
Sequence: MDKNKIIVFDTTLRDGEQSPGCSMNTEEKIKVALQLEKLGVDVIEAGFAAASPGDFDAVSRIAQIIKNSSICSLARAVDNDIKQAGLAVQSAAKSRIHTFIATSPIHMQYKLKMSGDEVIKRAIRAVEYAKTFVDDVEFSLEDAGRSEIPFMKEVMDAVIGAGAKTINLPDTVGYRLPTELGAMVKELSAYAGDRAIISVHNHNDLGLATANTLAAVLNGARQIEVTINGLGERAGNSALEEAVMAIKTRKDAFGDLYTTINTPEIYATSRLVATITGVEPQQNKAIVGKNAFAHESGIHQDGVLKHQETYEIMKPEDVGVIKDSTLILGKHSGRAAFRDKIVQLGFDKVSDDELNAAFERFKVLADNKKEISDEDVRMLITDEALNHDKTYDLIGLQISDCTNGVPTAAVAIKYKDEIIKDAAIGDGTMDAIFKTIDRITGFSGELKDYKVISVTEGKDALAKVTTRVSFDETSPAFVGHGLSIDTMLATAKAYIGALNSYLSQKKRLSKSSEHQV
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: MNMG_LACDB
Sequence: MKTYVSNEYDVIVVGAGHAGCEAALASARMGEKTLLLTISLDMVAFMPCNPSVGGPAKGTVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQADKWDYHEEMKRTIENTPNLTLRQAVVDDLIVEDGECRGVVTNTGARYRAKSVVLTTGTAARGRIFIGELNYSSGPNNTIPAIKLSESLERLGFKLRRFKTGTPPRVNRHTIDYSKTEEEPGDKEPRHFSFTSRDEDYLTDQTSCWMTYTNPKTHEIINENLDRSPMFSGDIVGVGPRYCPSIETKVVRFADKDRHQIFLEPEGRKTEEIYVGDFSTSMPEEVQLEMLHTVAGLEKVEMMRPGYAIEYDVVDPWQLTHTLETKRIKHLYTAGQMNGTSGYEEAAGQGLIAGINAALSAEGKPAFTLGRDEAYIGVLIDDLVTKGTEEPYRLLTSRAEYRLLLRHDNADLRLTEKGHDLGLIDDDRYAEFLAKKELIQEDLDRLGEITVHPTIAVNEYLAGLGQTDLNGGVKADVFLRRPRVTVEDVERLTGQKLAGDRYVKEQVEIDIKYAGYIKKQEIQVARLRRQEAKKIPKDIDYDQIEGLATEAREKLAKIRPETLAQAERISGVNPADLAILSVYVQNGKYAKVQK
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: S35F3_HUMAN
Sequence: MKKHSARVAPLSACNSPVLTLTKVEGEERPRDSPGPAEAQAPAGVEAGGRASRRCWTCSRAQLKKIFWGVAVVLCVCSSWAGSTQLAKLTFRKFDAPFTLTWFATNWNFLFFPLYYVGHVCKSTEKQSVKQRYRECCRFFGDNGLTLKVFFTKAAPFGVLWTLTNYLYLHAIKKINTTDVSVLFCCNKAFVFLLSWIVLRDRFMGVRIVAAILAIAGIVMMTYADGFHSHSVIGIALVVASASMSALYKVLFKLLLGSAKFGEAALFLSILGVFNILFITCIPIILYFTKVEYWSSFDDIPWGNLCGFSVLLLTFNIVLNFGIAVTYPTLMSLGIVLSIPVNAVIDHYTSQIVFNGVRVIAIIIIGLGFLLLLLPEEWDVWLIKLLTRLKVRKKEEPAEGAADLSSGPQSKNRRARPSFAR
What is the function of this protein?
Mediates thiamine transport.
What are the official names of this protein?
Solute carrier family 35 member F3, Thiamine transporter SLC35F3.
What is the protein family that this protein belongs to?
Belongs to the SLC35F solute transporter family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PSTB_GEOMG
Sequence: MNTKVKIDKLNVHFGQTHAVKDVSIDVPENTVTAIIGPSGCGKSTMLRSLNRMHDLFPNARVTGKVLLDGNDIYDRKVDPVSIRRRVGMVFQKPNPFPAMSIYDNVVAGYKLNGRVKKSDADEIVETSLRRVALWDEVKDRLKSNSMELSGGQQQRLCIARTIAVQPEVILMDEPASALDPISTLKIEELIEELTEKYTIIIVTHNMQQAARVSDYTAFFYMGDLVEWGETKKLFTTPEKKQTEDYITGRFG
What is the function of this protein?
Part of the ABC transporter complex PstSACB involved in phosphate import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphate import ATP-binding protein PstB, ABC phosphate transporter, Phosphate-transporting ATPase.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: GCSPB_BACC3
Sequence: MKNQDQALIFEVSKEGRIGYSLPKLDVEEVKLEDVFESDYIRVEDAELPEVSELDIMRHYTALSNRNHGVDSGFYPLGSCTMKYNPKINESVARFAGFANIHPLQDEKTVQGAMELMYDLQEHLIEITGMDTVTLQPAAGAHGEWTGLMLIRAYHEANGDFNRTKVIVPDSAHGTNPASATVAGFETITVKSNEHGLVDLEDLKRVVNEETAALMLTNPNTLGLFEENILEMAEIVHNAGGKLYYDGANLNAVLSQARPGDMGFDVVHLNLHKTFTGPHGGGGPGSGPVGVKADLIPYLPKPILEKTENGYHFNYDRPEAIGRVKPFYGNFGINVRAYTYIRSMGPDGLRAVTEYAVLNANYMMRRLAPFYDLPFDRHCKHEFVLSGRRQKKLGVRTLDIAKRLLDFGYHPPTIYFPLNVEECIMIEPTETESKETLDGFIDKMIQIAKEVEENPEVVQEAPHTTVIKRLDETMAARKPVLRYAKPAPVQV
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Probable glycine dehydrogenase (decarboxylating) subunit 2, Glycine cleavage system P-protein subunit 2, Glycine decarboxylase subunit 2, Glycine dehydrogenase (aminomethyl-transferring) subunit 2.
What is the protein family that this protein belongs to?
Belongs to the GcvP family. C-terminal subunit subfamily.
Protein: PROQ_AERS4
Sequence: MENTEKLKNSKEIVAYLVEKFPACFIAEGEAKPLKIGIFQDLAERLADDARVSKTMLRSALRQYTSSWRYLHGLKAGQARVDLDGNPGELLTEEHIEHAKQALKESKERVFASRRTNNKEEKAKQPRRPAPRKADAAAKSDKPKAAPKAVVADAPLVKVDAANLKVDQGVRVVLGKSPVPATIKEVTKDDVQVQLQTGMMLQVKFEHLVL
What is the function of this protein?
RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.
What are the official names of this protein?
RNA chaperone ProQ.
What is the protein family that this protein belongs to?
Belongs to the ProQ family.
What are the subcellular locations of this protein?
Cytoplasm.