PharMolix/UniProtQA huggingface dataset:
Protein: RL36A_BOVIN
Sequence: MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L36a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL42 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHK_LACLA
Sequence: MTEYNSEAYLKKLDKWWRAATYLGAGMIFLKENPLFSVTGTPIKAENLKANPIGHWGTVSGQTFLYAHANRLINKYDQKMFYMGGPGHGGQAMVVPSYLDGSYTEAYPEITQDLEGMSRLFKRFSFPGGIGSHMTAQTPGSLHEGGELGYVLSHATGAILDQPEQIAFAVVGDGEAETGPLMTSWHSIKFINPKNDGAILPILDLNGFKISNPTLFARTSDVDIRKFFEGLGYSPRYIENDDIHDYMAYHKLAAEVFDKAIEDIHQIQKDAREDNRYQNGEIPAWPIVIARLPKGWGGPRYNDWSGPKFDGKGMPIEHSFRAHQVPLPLSSKNMGTLPEFVKWMTSYQPETLFNADGSLKEELRDFAPKGEMRMASNPVTNGGVDSSNLVLPDWQEFANPISENNRGKLLPDTNDNMDMNVLSKYFAEIVKLNPTRFRLFGPDETMSNRFWEMFKVTNRQWMQVIKNPNDEFISPEGRIIDSQLSEHQAEGWLEGYTLTGRTGAFASYESFLRVVDSMLTQHFKWIRQAADQKWRHDYPSLNVISTSTVFQQDHNGYTHQDPGMLTHLAEKKSDFIRQYLPADGNTLLAVFDRAFQDRSKINHIVASKQPRQQWFTKEEAEKLATDGIATIDWASTAKDGEAVDLVFASAGAEPTIETLAALHLVNEVFPQAKFRYVNVVELGRLQKKKGALNQERELSDEEFEKYFGPSGTPVIFGFHGYEDLIESIFYQRGHDGLIVHGYREDGDITTTYDMRVYSELDRFHQAIDAMQVLYVNRKVNQGLAKAFIDRMKRTLVKHFEVTRNEGVDIPDFTEWVWSDLKK
What are the official names of this protein?
Probable phosphoketolase.
What is the protein family that this protein belongs to?
Belongs to the XFP family.
Protein: TMCAL_STAS1
Sequence: MKSVALVTEYNPFHNGHLYHAQQSKSITNSDISIAIMSGNFVMRGQPAIYNKFTRAKMALRAVDLVVELPAYASVSAGQYFAKTAVQIADYLNVSHLSFGSESGNMDDFLSLAQSIDKIEQSPLFLEKLKEGKSYPRILSELITDNDLLSSPNNTLGLSYVRAIQTYAPSIQPWTISRFQSAHHDNEISHQTFASGTSIRQSLMNQTDLWKDVVPCEIHKHYERPHISIEDTFNYLKYAILSQDATSLAQIYTMSEGIENRILQTIEQATSFEHLMTLLKTKRYTYTHIQRLLMNILLNFKKHDEPASINAVRILGMSERGQQYLKQIKKSFPERNFVTQVNKQNANLFTNEIHATKIYNLISGQTANDFNTPVIRI
What is the function of this protein?
Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates.  First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.
What are the official names of this protein?
tRNA(Met) cytidine acetate ligase.
What is the protein family that this protein belongs to?
Belongs to the TmcAL family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DCM_ECO57
Sequence: MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENHWSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPAHHPHYAFRFIDLFAGIGGIRRGFESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFNEDIRDITLSHKEGVSDEAAAEHIRQHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRPAMFVLENVKNLKSHDQGKTFRIIMQTLDELGYDVADAEDNGPDDPKIIDGKHFLPQHRERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYRYAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMATGEKDFDDPLNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLLEPKIKQAVALRQQEAQHGRRSR
What is the function of this protein?
This methylase recognizes the double-stranded sequence 5'-CCWGG-3', methylates C-2 on both strands.
What are the official names of this protein?
DNA-cytosine methyltransferase, Probable type II methyltransferase M.Eco9331DcmP, M.Eco9331DcmP.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Protein: ACCA_SYNC1
Sequence: MQFYLDFEKPLVELEQKLSELRDYSTDEVDFSGEIQRLEKKAEKLRREIFSNLNRWQVTQLARHVNRPFTLDFVEHVFTDWFEVHGDRNFRDDPALVCGFARLDGQPCAVIGHQKGRDTKEKVYRNFGMPNPEGYRKALRVMQMAEQFGLPIFTFVDTPGAFPGIGAEERGQAEAIARNLREMAALKVPVIVTVTGEGGSGGALAVAVGNRVLMMENAVYSVISPEGCAAILWKDGAKGPVAAEALKLTAGDIQNLGCVIDEVIPEPLGGAHSDHKAAAEQVRICLKKHLDDLKDLSSDELREQRYQKLRAMTMVQE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha, ACCase subunit alpha, Acetyl-CoA carboxylase carboxyltransferase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the AccA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IMPX_YEAST
Sequence: MQKSILLTKPDGTQSNLHSIKTETPTTVEFDSEQMERGHRERGRSKKKRGERDSNVSSLSRSRSRASSRSRVREEEFLKWTVLRQDPSMRLRVVDVDSEEEGEGNDEDDDDGDGDDMDEEESDEEQVSDIENDLEIDEEFHYDLGMKVLPNFCTSINEVLDSSKPWIAKYEISIRGHENEDVSLEQLDGGYVRAMQLLTKGAGAEAGNQRSFILYTDLSSESTYALTYLMGAAVNQGDTVYIVHWEPSKPTDDSQMFANVARIRKHVMHLFDCVAGVLDDLDVVVLSLTHPYPKHLLNEMIHGLKPVALCCSLSVILSTLQNFVCSVPILAVRKKLKRAKRKGISE
What is the function of this protein?
Controls the nucleo-mitochondrial dependence of galactose, maltose and raffinose utilization.  Becomes essential in the absence of functioning mitochondria.
What are the official names of this protein?
Sugar utilization regulatory protein IMP2.
Protein: RL21_CORGL
Sequence: MYAIVKTGGKQYKVAEGDLVKVEKIEGEPGASVALTPVLLVDGADVTTAADKLASVSVNTEIVEHTKGPKIKILKYKNKTGYKKRQGHRQPLTVLKVTGIK
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: PROB_THET8
Sequence: MRPGLSAKRLVVKVGSAVLTGERGLDLEAMAEIARQVAALREEGREVVLVSSGAVAAGMRRLGLKERPKDMPKKQALAALGQPLLMAFWQEAFAPFGLPVAQVLLTAEDLSSRSRYLNAKATLRALLDLGAIPVINENDTVAFEEIRFGDNDQLSARVAALVEAGLLALLSDVDALYEEDPKKNPQARPIPEVESVEAVLAHAGEENPLGSGGMKSKLLAARIAGRVGIPTLLLPGKRPGVLLQALSGAPLGTYFHARRRYRGEKAWLFGLLRPKGELVLDRGAVRALKERGASLLPAGVKEVRGRFSRGEAVRLLSEEGEEVGVGLANYASEEIARIKGRRSAEIEAVLGYRYTEEVVHRDHLALKEEA
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_SALCH
Sequence: MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEPLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIVRFAEAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVDGGDLAFDREEIPLQPAGWQPEEDDTSLEALRLDVIEVK
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAPF_SHIFL
Sequence: MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLNPRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHISDQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR
What is the function of this protein?
Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
What are the official names of this protein?
Peptide transport system ATP-binding protein SapF.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VE7_HPV61
Sequence: MHGQVATIKDIVLEERPEVVDLHCNEQLLDSSESEEEDSVREQLVEQAQQAYRVVTTCGICKCPVRLVVQCGDADLKVLHELLLGDLSIVCPGCA
What is the function of this protein?
Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle.  Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.  E7 protein has both transforming and trans-activating activities.  Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes.  Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.  Also plays a role in the inhibition of both antiviral and antiproliferative functions of host interferon alpha.  Interaction with host TMEM173/STING impairs the ability of TMEM173/STING to sense cytosolic DNA and promote the production of type I interferon (IFN-alpha and IFN-beta).
What are the official names of this protein?
Protein E7.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E7 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus. Note=Predominantly found in the host nucleus.
Protein: RBL_PROMS
Sequence: MSKKYDAGVKEYRDTYWTPEYVPLDTDLLACFKCTGQEGVPREEVAAAVAAESSTGTWSTVWSELLTDLEFYKGRCYRIEDVPGDPEAFYAFIAYPLDLFEEGSITNVLTSLVGNVFGFKALRHLRLEDIRFPIAFIKTCGGPPNGIVVERDRLNKYGRPLLGCTIKPKLGLSGKNYGRVVYECLRGGLDLTKDDENINSQPFQRWRERFEFVAEAVKLAQQETGEVKGHYLNCTANTPEELYERAEFAKELDMPIIMHDYITGGFTANTGLANWCRKNGMLLHIHRAMHAVIDRHPKHGIHFRVLAKCLRLSGGDQLHTGTVVGKLEGDRQTTLGYIDNLRESFVPEDRSRGNFFDQDWGSMPGVFAVASGGIHVWHMPALLAIFGDDSCLQFGGGTHGHPWGSAAGAAANRVALEACVKARNAGREIEKESRDILMEAAKHSPELAIALETWKEIKFEFDTVDKLDVQG
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Carboxysome.
Protein: LPXC_VIBA3
Sequence: MIRQRTLKEIVKTTGVGLHSGRKVTLTLRPAAANTGIVYRRTDVNPPVDFPADPASVRDTMLCTALVNDEGVRISTVEHLNAALAGMGIDNIIVEVDAPEIPIMDGSASPFVYLLQQAGVETLNAAKRFIRIKKPIRFEDGDKWAEFVPFNGFRMDFEIEFNHPAIESDEQHLLFDFSSQGFVKEISRARTFGFMRDIEYLQSQNLCLGGSFDCAIVLDEYRILNEEGLRFENEFVTHKVLDAIGDLYMCGHAIIGEFRAYKSGHGLNNQLLRAVLADAEAWEWATFEEEVGSPVAFAEPGMVLA
What is the function of this protein?
Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.
What are the official names of this protein?
UDP-3-O-acyl-N-acetylglucosamine deacetylase, UDP-3-O-acyl-GlcNAc deacetylase, UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase.
What is the protein family that this protein belongs to?
Belongs to the LpxC family.
Protein: RL21_KORVE
Sequence: MYAVIRAGSKQFRVSPGDVIKVDSAPHSESGKLEIADVLAVSNGQGKFGSPENATVTAEILGDGRGDKILVFHYKRKKQYKKLQGHRQGFTALKITEINVDGEKFTIDDMPKKEAAPAKARRSTKKAAAAE
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: URE2_PARPJ
Sequence: MIPGELLIDDGEHELNAGRATVTVVVSNTGDRPVQIGSHYHFYEVNEALAFDREAARGFRLNIAAGTAVRFEPGQERTVELVELAGERIVYGFNGKVMGKL
What are the official names of this protein?
Urease subunit beta, Urea amidohydrolase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the urease beta subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAE1_SULIN
Sequence: MLVLGIESTAHTFGVGIAKDQPPYILANERDAFVPKEGGMKPGDLLKHHAEASGTILRRALEKANISINDINYIAVALGPGIGPALRVGATLARALSLKYNKKLVPVNHSIGHIEIGYLTTEAKDPLILYLSGGNTIITTFYKGRFRIFGETLDIALGNMMDVFVREVNLAPPYIINGKHAIDICSEKGSKLLKLPYVVKGQDMSFSGLLTAALRLVGKEKLEDICYSIREIAFDMLLEATERALALTSKKELMIVGGVAASVSLRKKLEELGKEWDVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVDEVDIPWRN
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1, tRNA threonylcarbamoyladenosine biosynthesis protein Kae1.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBACT_NITMO
Sequence: MNMRYTLMPERREGPVDPMPQSPSPSDEGGGPRRPETGSPDKDNLLKRMRKVDPKQAERYRQRTGE
What is the function of this protein?
May function as a protein modifier covalently attached to lysine residues of substrate proteins.  This may serve to target the modified proteins for degradation by proteasomes.
What are the official names of this protein?
Prokaryotic ubiquitin-like protein UBact.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-like protein UBact family.
Protein: FDNH_SHIFL
Sequence: MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKACQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMHCEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKCTLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEGVGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHYIGIGPNKEVDDDEEDHHE
What is the function of this protein?
Formate dehydrogenase allows the bacterium to use formate as major electron donor during anaerobic respiration, when nitrate is used as electron acceptor.  The beta subunit FdnH is an electron transfer unit containing 4 iron-sulfur clusters; it serves as a conduit for electrons that are transferred from the formate oxidation site in the alpha subunit (FdnG) to the menaquinone associated with the gamma subunit (FdnI) of formate dehydrogenase-N.  Formate dehydrogenase-N is part of a system that generates proton motive force, together with the dissimilatory nitrate reductase (Nar) (By similarity).
What are the official names of this protein?
Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit, Anaerobic formate dehydrogenase iron-sulfur subunit, Formate dehydrogenase-N subunit beta, FDH-N subunit beta.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: ACLA_ASPOR
Sequence: MDQPSPSAEDSQPERQSTGTRGTRFWAVFVSLCFASFVASLDITAITTALPTVTRELDGGENYVWIANSYTLASAVVQPLIGQISNIVGRRNPMIILMCLFALGSGICGGATSTGMMIAGRTVQGLGAGGILLLLEVIVCDLVPLRERAQYVGIALSTCALGISLGPLVGGALVQHATWRWVFYINLPCAGVALVALVLCLNVQHKREVSWGRALARVDWVGNTIFIAAICAIMYALVIGGSVHPWSSYQVLVPLVLGAFGWVLFHIFEASPYCLEPTMPPRLFRNRTSMTAYVLAFLAAMLMQWVVYFLTLFFQTVKGQSTTMSGVDVIPFTGFMIPSAIVGGAIMSKTGVYRPLHWAGFALLSICMGVFSTWDAGTPRAEWVILQCLVGLGHGLLLTSVLPAIQAALPESDNAAATSAYAFLRSFGFVWGVEIPAVVFNGQVDRFISRVHDATVRNKLAHGGAYSLAGTSFLSQLGDEADAVRSTYTDSLRTVWQVGMAFALLGFALVVVEKHIELRTTLETDFGLEGSENRAATSVEGVETGPVSKAQ
What is the function of this protein?
MFS efflux transporter; part of the gene cluster that mediates the biosynthesis of aspirochlorine (or antibiotic A30641), an unusual halogenated spiro compound with distinctive antifungal properties due to selective inhibition of protein biosynthesis, and which is also active against bacteria, viruses, and murine tumor cells (PubMed:25302411).
What are the official names of this protein?
MFS efflux transporter aclA, Aspirochlorine biosynthesis protein A.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: C124A_XENLA
Sequence: MPKKFQGENTKSAVARARKAEAKAVSDGKRQKEIEDAYWQDDDKHVARKGQRKEDKEKKRLEQLERKKESQRLLDEEDSKMKAKPTKPAAPSKVTRAEIEETLCKEEEHKATTEKPKTHLEMPLEENVNRRVLEEGEVEARTVEDAIAALSVGKELDRHPERRMKAAFAAFEEINMPLLKQENPNMRLSQLKHLLKKEWMKSPENPMNQQHAMYNSH
What is the function of this protein?
Required for proper progression of late cytokinetic stages.
What are the official names of this protein?
Coiled-coil domain-containing protein 124-A.
What is the protein family that this protein belongs to?
Belongs to the CCDC124 family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody.
Protein: VES_ECODH
Sequence: MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIAANGEFSLFPGMERIVTLLEGGEMLLESADRFNHTLKPFQPFAFAADQVVKAKLTAGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFDGRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
What are the official names of this protein?
Protein Ves.
What is the protein family that this protein belongs to?
Belongs to the Ves family.
Protein: PTFAH_ECOLI
Sequence: MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGMLAREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAASSDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIVASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVSRAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLTSDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSLMKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II FruAB PTS system is involved in fructose transport.
What are the official names of this protein?
Multiphosphoryl transfer protein, MTP, Diphosphoryl transfer protein, DTP, Phosphotransferase FPr protein, Pseudo-HPr.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RRF_LISMC
Sequence: MSKEVLSKSKEKMEKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAATPVNQMASISVPEARMLLITPYDKTILGEIEKAILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQKLTDESIKNIDSITKDKEAEILEV
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRM6_ASPFU
Sequence: MHSYIRPYQHVALRLPSELTKIVRLVPNTVVYLGKYGSFPANTIIGRPFYLTFEIIDVSGENNDNCLRIVPPAELHAETLIADGEGEGDDVEVNEEGIPIRTNREIVDDASTQKMTAEEIEALKKVSTGAGREIIEKLLESHSALDQKTAFSLAKYTLRKRKKFLKRFTVLPVDVSLLTNYMLEGKEAMKTMELRDESIGLIGCWGNVHHGGQSSFEGAVASKPNGRYLVIDETGGLVVAAMAERMGILYPHDQEDEDQELAEGSEENGERQQTNAMAQALARRRHMAASGNSITVIHANKQPSLSLLRYFGYDQDNPDESHPLYKHMKTVSWMQLLDPHADTIYANEPEVIPDETLATFKSNRRSAYYKKRSRWERVRRVVDEARAGNFDGLIVATLMEPASVLKHTVPLLAGSAPVVVYSPTVEPLTELADLYSTPRRTAYITRKREIIAQHSLQQSLQGQSQDNEKKPQEPDFSELDKDFALDPSLLLAPTIETSRVRAWQVLPGRTHPLMSGRGGAEGYIFHAIRVFPSHQNIQAAGNPSRKKRKVAAQQESATPAESGSGVDVEMQS
What is the function of this protein?
Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
What are the official names of this protein?
tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit trm6, tRNA(m1A58)-methyltransferase subunit trm6, tRNA(m1A58)MTase subunit trm6.
What is the protein family that this protein belongs to?
Belongs to the TRM6/GCD10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YWV3_CAEEL
Sequence: MFNFITFILFAVVCISYCHKSRGRRHFGDEYRINTPACDIVCEGQWKSEFHANFHKIYDTEYFEIPLDTAIVKNRANLKMFCSSTIQKYSCLRNECKIQRTPWSAEKHICVGHFDNFDRNINCLSLTDKYVQRECSNVCNSIKIEISQAEIDRMAEMDFSRQEKSEFVEQNKHCNVIACYQLCHEYIISKVCIDSAVAARSVVKSYYDSYLEREYTELNKDDQDELYSSFCRRVTPGQDENEFTANMTRYNNLTLDRMKNDIRSVFSILD
What are the official names of this protein?
Uncharacterized protein B0403.3.
What are the subcellular locations of this protein?
Secreted.
Protein: PFPB_RICCO
Sequence: MATPNSGRAASVYSEVQSSRIEHVLPLPSVLNHPFKIVQGPPSSAAGNPDEIAKLFPNLFGQPSAMLVPDVADSLDSNQQLKIGLVLSGGQAPGGHNVISGIFDYLQDRAKGSILYGFRGGPAGIMKCNYVQLTADYIHPYRNQGGFDMICSGRDKIETPEQFKQAEETAGKLDLNGLVVIGGDDSNTNACLLAENFRSKNLKTRVIGCPKTIDGDLKCKEVPTSFGFDTACKIYSEMIGNVMIDARSTGKYYHFVRLMGRAASHITLECALQTHPNITIIGEEVAAKKLALKDVTDYIVDVICKRADLGYNYGVILIPEGLIDFIPEVQNLIAELNEILAHDVVDEGGLWKKKLTSQSLQLFEFLPVAIQEQLMLERDPHGNVQVAKIETEKMLIQMVETELEKRKQQGTYKAHFKGQSHFFGYEGRCGLPTNFDSTYCYALGYAAGALLHSGKTGLISSVGNLGAPVAEWTVGGTALTSLMDVERRHGKFKPVIKKAMVELEGAPFKKFASLREEWALKNRYVSPGPIQFMGPGSDAASHTLLLELGSVA
What is the function of this protein?
Catalytic subunit of pyrophosphate--fructose 6-phosphate 1-phosphotransferase.  Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis.  Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis.
What are the official names of this protein?
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase subunit beta, PFP, 6-phosphofructokinase, pyrophosphate dependent, PPi-PFK, Pyrophosphate-dependent 6-phosphofructose-1-kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_METFK
Sequence: MSKNVVVIGTQWGDEGKGKIVDWLTDHAQGVVRFQGGHNAGHTLVIGQGASQKEYKLNLVPSGIVREGVNCYIGNGVVLDANHLLFEIDGLEKAGLEVRNRLKVSPGCPLILEYHVRLDKAREAAREPGRKIGTTGKGIGPTYEDKVARRALRVYDLFYPERFAEKLREVLDYHNFVLTKYLNAEAVDYQQQLDEALSKAPLLQPLVTDISAALYEANKAGQNLLFEGAQGTLLDVDHGTYPYVTSSNCISGQAAAGTGVGPSMLHYVLGITKAYTTRVGGGPFPSELDIETEDSPGFQMSDKGREIGTVTKRKRRCGWFDAAALRRSARINGLTGLCITKLDVLDGIKELNICTGYELDGKPVDLLPVGADDVARCQPVYETLPGWDESTFGISRWEDLPQNARNYLKRLEALCEVPVDIVSTGPERDETIVLRHPFGA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACES_MYXGL
Sequence: VPSPRPQNATVMVWIFGGGFAYGTSSLNVYDGRYLAQAEGAIVVSMNYRVGALGFLSLPGSPVPGNAGLFDQQLALRWVHGNIHRFGGNPQSVTLFGESAGSASVAPHLLSRHSQQFFQRAILQSGTLNAPWATVEDTEARRRAEALAQALGCPTDDDNELLNCLYARPPQEIVSKEGDVVIEPSIFRFPFVPVVDGHFIIDSPIVLLQQGIFKKTDLLLGVNRNEGSFFLIYGAPGFSKDHESLISREDFLENIPMIVPQGNEVSVDAIVLQYTDWLAQNDALKNRDAIEDIVGDYNVICPVVEMATRYAEFGNNVYFYFFNQRASNLPWPQWMGVI
What is the function of this protein?
Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
What are the official names of this protein?
Acetylcholinesterase, AChE.
What is the protein family that this protein belongs to?
Belongs to the type-B carboxylesterase/lipase family.
What are the subcellular locations of this protein?
Synapse. Secreted. Cell membrane; Peripheral membrane protein.