PharMolix/UniProtQA huggingface dataset:
Protein: BIOD_RHIWR
Sequence: MTRAIVVTATDTDVGKTVFSAGLAGLLDGCYWKPVQAGLADGTDSDTVRRLSGLPDDRILPEAYRLETPASPHHAAAIDNVVIDPALLAPPPCDRRLVIEGAGGLLVPLAGGLLFADIFAGWRFETVVVARTALGTINHSLLTIEALRARDIPILGIAFIGDPQEESERTIAAIGGVRRLGRLPRLDPLDAGTLAAAFAAAFSPEDFAP
What is the function of this protein?
Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
What are the official names of this protein?
ATP-dependent dethiobiotin synthetase BioD, DTB synthetase, DTBS, Dethiobiotin synthase.
What is the protein family that this protein belongs to?
Belongs to the dethiobiotin synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y799_STAAW
Sequence: MAKKAPDVGDYKYGFHDDDVSIFRSERGLTENIVREISNMKNEPEWMLDFRLKSLKLFYKMPMPQWGGDLSELNFDDITYYVKPSEQAERSWDEVPEEIKRTFDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEEKGIIFKDTDSALQENEELFKKYFASVVPAADNKFAALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLIIADEGASVHYVEGCTAPVYTTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRTFVYENGNMEWVDGNLGSKLTMKYPNCVLLGEGAKGSTLSIAFAGKGQVQDAGAKMIHKAPNTSSTIVSKSISKNGGKVIYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYNEVFNDQISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAVEMNRLIKFEMEGSIG
What are the official names of this protein?
UPF0051 protein MW0799.
What is the protein family that this protein belongs to?
Belongs to the UPF0051 (ycf24) family.
Protein: YIDC_STAS1
Sequence: MKKKALLPLLLGVMVFLAGCDYSKPENRDGFFYNTFYVPMDNVIHWLGTSFNNDYGLAIVVLVLVIRIVLLPFMLSNYKNSHMMREKMKVAKPDIDAIQEKVKRSRTQEEKMAANSEMMEVYKKYDMNPMKSMLGCLPILIQMPIIMGLFFVLKYPSSGGFTEHPYFLWFNLAKPDIWITIIAGILYFLQAYVSSKSMPAEQRQMGYMMMVISPIMIVWISFSSVSALGLYWSVSAAFLIVQTQVANMYYSKLAQREVAPMIEAMEKNKAEASGKGKNTQVVSKKNKKK
What is the function of this protein?
Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane.  Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins.
What are the official names of this protein?
Membrane protein insertase YidC, Foldase YidC, Membrane integrase YidC, Membrane protein YidC.
What is the protein family that this protein belongs to?
Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HISZ_PSYA2
Sequence: MLPDGVADVLFEDAHKQEVLRHQLTQQLITHGYQLVSPPMIEFTESLLSGASEDLKRQTFKIIDQLTGRLMGIRADITPQILRIDAHHGGDGIARYCYAGDVIHTLPSGLFGSRTPLQLGAEIFGCESIAADIELIDVLFSMINSLDMSAVLHVDLGHVTIFKRLAELAALSASDTEQLMQLYANKNLPELKQVCQVLPMGSDFYTLARFGHDIANLLGRLSENAQQDTKIVTAIDELQRLKAHLQVQWQCAVSIDVTELSGYHYHTGIVFNGYINSETQPLVRGGRFDGMKSNQLATNQPRQATGFSMDVSRLLAHTQLDAPFIVLIDYDAFNNLDSAQRQLLLQQVASLRQQGYRVTMPLTAEDMPVGLTHRLSLADNQWRLHAV
What is the function of this protein?
Required for the first step of histidine biosynthesis.  May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
What are the official names of this protein?
ATP phosphoribosyltransferase regulatory subunit.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEPL1_CAEEL
Sequence: MYTRFGPPIVFLISCYALILCGTVDALPRAPYFNDDINKTTTTSEDKTVGNTVVEEEKKTYTVGDSEGYQEASRLLQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKWRESTFDLTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRRFDDLKEYMSIIDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQNTDPRIVTNYILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRKYFDANAKNTTLDMITDLQEAFRNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWRNNFYYRRLLEPVNRFEFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGENIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW
What is the function of this protein?
Probable cell surface protease.  Required to control the neuronal innervation of pharyngeal pumping.
What are the official names of this protein?
Neprilysin-1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M13 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type II membrane protein.
Protein: Y2116_PSEAE
Sequence: MPEPTFHELAQLPPPVLRQLIRRGDYTGHTSGLGQRHLQANLVILQKSWADEFLRFCALNPRACPLLDVSEPGSPHFARLGADIDVRSDLPRYRVHRRGQEPVEVSDIGTFWEADFVAFAIGCSFSFEQALLDAGIGLRHLELGRNVTMYRSSIATRPSGRLAGPTVVSMRPLKAAEAIRAIQVTSRFPMTHGAPLHLGDPALIGIRDLARPDYGDPVPLAADEIPLFWACGVTPQAVLAEVQPELYISHAPGHMLVSDRLYDEL
What are the official names of this protein?
Putative hydro-lyase PA2116.
What is the protein family that this protein belongs to?
Belongs to the D-glutamate cyclase family.
Protein: TDH_XANAC
Sequence: MKALVKREANKGIWLEQVPVPTPGPNEVLIKLEKTAICGTDLHIYLWDEWSQRTIEPGLTIGHEFVGRVAELGSAVTGYQIGQRVSAEGHIVCGHCRNCRGGRPHLCPNTVGIGVNVNGAFAEYMVMPASNLWPIPDQIPSELAAFFDPYGNAAHCALEFDVIGEDVLITGAGPIGIIAAGICKHIGARNVVVTDVNDFRLKLAADMGATRVVNVSKTSLKDVMADLHMEGFDVGLEMSGNSRAFNDMLDCMYHGGKIAMLGIMPRGAGCDWDKIIFKGLTVQGIYGRKMYETWYKMTQLVLSGFPLHKVLTHQLPIDDFQKGFDLMEEGKAGKVVLSWN
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 4CL1_TOBAC
Sequence: MPMETTTETKQSGDLIFRSKLPDIYIPKHLPLHSYCFENISEFSSRPCLINGANDQIYTYAEVELTCRKVAVGLNKLGIQQKDTIMILLPNSPEFVFAFMGASYLGAISTMANPLFTPAEVVKQAKASSAKIIITQSCFVGKVKDYASENDVKVICIDSAPEGCLHFSELTQSDEHEIPEVKIQPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENANLYMHSEDVLMCVLPLFHIYSLNSILLCGLRVGAAILIMQKFDIAPFLELIQKYKVSIGPFVPPIVLAIAKSPIVDSYDLSSVRTVMSGAAPLGKELEDAVRTKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFDIKSGACGTVVRNAEMKIVDPDTGCSLPRNQPGEICIRGDQIMKGYLNDPEATTRTIDKEGWLHTGDIGFIDEDDELFIVDRLKELIKYKGFQVAPAEIEALLLNHPNISDAAVVPMKDEQAGEVPVAFVVRSNGSAITEDEVKDFISKQVIFYKRVKRVFFVETVPKSPSGKILRKDLRARLAAGVPN
What is the function of this protein?
Carboxylate--CoA ligase that may use 4-coumarate as substrate.  Follows a two-step reaction mechanism, wherein the carboxylate substrate first undergoes adenylation by ATP, followed by a thioesterification in the presence of CoA to yield the final CoA thioester.
What are the official names of this protein?
4-coumarate--CoA ligase 1, 4CL 1, 4-coumaroyl-CoA synthase 1.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
Protein: NAC71_ORYSJ
Sequence: MECGGALQLPPGFRFHPTDDELVMYYLCRKCGGLPLAAPVIAEVDLYKFNPWDLPERAMGGEKEWYFFSPRDRKYPNGQRPNRAAGTGYWKATGADKPVGSPRAVAIKKALVFYAGKPPKGVKTNWIMHEYRLADVDRSAAARKLSKSSHNALRLDDWVLCRIYNKKGVIERYDTVDAGEDVKPAAAAAAAKGGRIGGGGGAAAMKVELSDYGFYDQEPESEMLCFDRSGSADRDSMPRLHTDSSGSEHVLSPSPSPDDFPGGGDHDYAESQPSGGCGGWPGVDWAAVGDDGFVIDSSLFELPSPAAFSRAAGDGAAFGDMFTYLQKPF
What is the function of this protein?
Transcription activator that binds to the promoter of the stress response gene LEA19.  Involved in tolerance to abiotic stresses.
What are the official names of this protein?
NAC domain-containing protein 71, ONAC071, OsNAC5.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y148_ARCFU
Sequence: MEAARGWDEEVMKWLAVAICLAMVGMAVMPAFQPLNLAFELYYGHHESLPITAASAAYEGIVITATLAAAAATAELVHLLLQQFL
What are the official names of this protein?
Uncharacterized protein AF_0148.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: YI046_YEAST
Sequence: MMCVCIPKKKLMDWRVYYIYSYVVCLYMCGSDCACICVLACVVQCVCFNVEMRL
What are the official names of this protein?
Uncharacterized protein YIL046W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: NDRG1_MOUSE
Sequence: MSRELHDVDLAEVKPLVEKGESITGLLQEFDVQEQDIETLHGSLHVTLCGTPKGNRPVILTYHDIGMNHKTCYNPLFNSEDMQEITQHFAVCHVDAPGQQDGAPSFPVGYMYPSMDQLAEMLPGVLHQFGLKSVIGMGTGAGAYILTRFALNNPEMVEGLVLMNVNPCAEGWMDWAASKISGWTQALPDMVVSHLFGKEEIHNNVEVVHTYRQHILNDMNPSNLHLFISAYNSRRDLEIERPMPGTHTVTLQCPALLVVGDNSPAVDAVVECNSKLDPTKTTLLKMADCGGLPQISQPAKLAEAFKYFVQGMGYMPSASMTRLMRSRTASGSSVTSLEGTRSRSHTSEGPRSRSHTSEGSRSRSHTSEDARLNITPNSGATGNNAGPKSMEVSC
What is the function of this protein?
Stress-responsive protein involved in hormone responses, cell growth, and differentiation.  Acts as a tumor suppressor in many cell types.  Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis.  Required for vesicular recycling of CDH1 and TF.  May also function in lipid trafficking.  Protects cells from spindle disruption damage.  Functions in p53/TP53-dependent mitotic spindle checkpoint.  Regulates microtubule dynamics and maintains euploidy (By similarity).  Has a role in cell trafficking notably of the Schwann cell and is necessary for the maintenance and development of the peripheral nerve myelin sheath.
What are the official names of this protein?
Protein NDRG1, N-myc downstream-regulated gene 1 protein, Protein Ndr1.
What is the protein family that this protein belongs to?
Belongs to the NDRG family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cell membrane. Note=Mainly cytoplasmic but differentially localized to other regions. Associates with the plasma membrane in intestinal epithelia and lactating mammary gland. Translocated to the nucleus in a p53/TP53-dependent manner. In prostate epithelium and placental chorion, located in both the cytoplasm and in the nucleus. No nuclear localization in colon epithelium cells. In intestinal mucosa, prostate and renal cortex, located predominantly adjacent to adherens junctions. Cytoplasmic with granular staining in proximal tubular cells of the kidney and salivary gland ducts. Recruits to the membrane of recycling/sorting and late endosomes via binding to phosphatidylinositol 4-phosphate. Associates with microtubules. Colocalizes with TUBG1 in the centrosome. Cytoplasmic location increased with hypoxia. Phosphorylated form found associated with centromeres during S-phase of mitosis and with the plasma membrane (By similarity).
Protein: Y2348_ARCFU
Sequence: MKSRSRKSVILQDYYRGDSNIEVAGYDTIRGNSLIDYIHKALRAYDIEGMKGFDRVRSEIPYSMKAVIGVLQALARIRLDPSRKNDREANRAAEILEHLRMLDEKLERWGVK
What are the official names of this protein?
Uncharacterized protein AF_2348.
Protein: TWS1B_XENLA
Sequence: MKPSFLHIPAAALLLCSLWILPIHCCNKALCASDVSKCLIQELCQCRPTDGNCSCCKECMLCLGTLWDECCDCVGMCNPRNYSDTPPTSKSTVEELHEPIPSLFRALTEGDTQLNWNIVTFPVVEELSHHENLVSFLETVNQPQQQNVSVQVSHSNEKEHMCTVVYFDDCMSIHQCKVSCESMGASKYRWFHNACCECVGPECIDYGSKTVKCVNCMV
What is the function of this protein?
Involved in dorsal-ventral patterning, permitting peak BMP signaling by antagonizing the residual anti-BMP activity of the cleavage products of chrd.  Functions to promote the formation of ventral mesoderm by increasing the activity of bmp7 and other BMPS.  Seems to antagonize BMP signaling by forming ternary complexes with chrd and BMPs, thereby preventing BMPs from binding to their receptors.  In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of chrd, which releases BMPs from ternary complexes.  May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation.
What are the official names of this protein?
Twisted gastrulation protein homolog 1-B.
What is the protein family that this protein belongs to?
Belongs to the twisted gastrulation protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: PYRG_ACIC1
Sequence: MAARQQTKHLFVTGGVASSLGKGLTASSLGNLLKARGLRVTMQKLDPYLNVDPGTMNPFQHGEVFVTDDGAETDLDIGHYERFLDTDLNGSANVTTGQIYSSVIAKERRGEYLGDTVQVIPHITNEIKDRIRGMAGRDVDVVITEIGGTVGDIESLPFLEAARQIRHEVGRDNVFFLHVSLLPYIGPSGELKTKPTQHSVAALRQVGITPDAIVCRADRPIPPNVKKKVSLMCDVDEEAVISAVDAPSIYDIPKVLHAEGLDAYVVRRLGLPFRDVDWTQWDELLRRVHDPANRVTIALVGKYVDLPDAYLSVIEALRAGGIANDAGVDVRWVASDTCETPGGAAKALQNVDGVVVPGGFGVRGIEGKLGALRYTRENGIPTLGLCLGLQCMVVEFARNVIGLAGANSTEFDPATPYPVIATMADQMEVVAGRRDMGGTMRLGSYPAILAPETLVHELYGCLEVRERHRHRYEVNNAYRQQLEAAGLVISGTSPDGQLVEFVELPRSVHPFYVATQAHPELRSRPTRPHPLFTGLIRAALLHRCPPIPLDTEPVPTAR
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: PSD_ESCF3
Sequence: MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDSEPAPLPAEEIEAEHDASPLVDDKKDQV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: MOB1_SCHPO
Sequence: MFGFSNKTAKTFRVRKTEAGTKHYQLRQYAEATLGSGSLMEAVKLPKGEDLNEWIAMNTMDFYTQINMLYGTITEFCTAASCPQMNAGPSYEYYWQDDKIYTKPTRMSAPDYINNLLDWTQEKLDDKKLFPTEIGVEFPKNFRKVIQQIFRRLFRIYAHIYCSHFHVMVAMELESYLNTSFKHFVFFCREFGLMDNKEYAPMQDLVDSMV
What is the function of this protein?
Has a role in promoting the onset of septum formation during the latter stages of mitosis.
What are the official names of this protein?
Maintenance of ploidy protein mob1.
What is the protein family that this protein belongs to?
Belongs to the MOB1/phocein family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Spindle pole body throughout mitosis, relocates to the medial ring during interphase.
Protein: RL27_PSEPF
Sequence: MAHKKAGGSTRNGRDSEAKRLGVKMYGGQVIKAGNIIVRQRGTQFHAGYGVGMGKDHTLFAKIEGVIKFEVKGAFGRRYVSVVAA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: OSPC3_SHIFL
Sequence: MKIPEAVNHINVQNNIDLVDGKINPNKDTKALQKNISCVTNSSSSGISEKHLDHCADTVKSFLRKSIAAQSYSKMFSQGTSFKSLNLSIEAPSGARSSFRSLEHLDKVSRHYLSEIIQKTHPLSSDERHLLSIIINSDFNFRHQSNANLSNNTLNIKSFDKIKSENIQTYKNTFSEDIEEIANHDFVFFGVEISNHQETLPLNKTHHTVDFGANAYIIDHDSPYGYMTLTDHFDNAIPPVFYHEHQSFFLDNFKEVVDEVSRYVHGNQGKTDVPIFNTKDMRLGIGLHLIDFIRKSKDQRFREFCYNKNIDPVSLDRIINFVFQLEYHIPRMLSTDNFKKIKLRDISLEDAIKASNYEEINNKVTDKKMAHQALAYSLGNKKADIALYLLSKFNFTKQDVAEMEKMKNNRYCNLYDVEYLLSKDGANYKVLEYFINNGLVDVNKKFQKVNSGDTMLDNAMKSKDSKMIDFLLKNGAILGKRFEI
What is the function of this protein?
ADP-riboxanase effector that inhibits host cell pyroptosis (PubMed:23684308, PubMed:34409271, PubMed:34671164).  Acts by mediating arginine ADP-riboxanation of host CASP4/CASP11, blocking CASP4/CASP11 autoprocessing (PubMed:34671164, PubMed:35338844, PubMed:35568036).  This prevents CASP4 activation and ability to recognize and cleave GSDMD, thereby inhibiting LPS-induced pyroptosis (PubMed:34671164).  ADP-riboxanation takes place in two steps: OspC3 first catalyzes ADP-ribosylation of target Arg, and then initiates a deamination to remove one N-omega group (PubMed:34671164).  Independently of its ADP-riboxanase activity, acts as an inhibitor of calcium signaling by inhibiting host calmodulin, preventing activation of the JAK-STAT signaling pathway in response to interferon-beta (PubMed:35568036).  Mechanistically, acts by binding to the apo form of calmodulin, preventing calcium-binding and ability to activate host CaMK2 (CAMKII), which is required to stimulate the JAK-STAT signaling pathway in response to interferon-beta (PubMed:35568036).
What are the official names of this protein?
Arginine ADP-riboxanase OspC3.
What is the protein family that this protein belongs to?
Belongs to the OspC family.
What are the subcellular locations of this protein?
Secreted. Host cytoplasm. Note=Secreted via the type III secretion system (TTSS).
Protein: TEAN2_HUMAN
Sequence: MDKFVIRTPRIQNSPQKKDSGGKVYKQATIESLKRVVVVEDIKRWKTMLELPDQTKENLVEALQELKKKIPSREVLKSTRIGHTVNKMRKHSDSEVASLAREVYTEWKTFTEKHSNRPSIEVRSDPKTESLRKNAQKLLSEALELKMDHLLVENIERETFHLCSRLINGPYRRTVRALVFTLKHRAEIRAQVKSGSLPVGTFVQTHKK
What are the official names of this protein?
Transcription elongation factor A N-terminal and central domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TCEANC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DAZL_DANRE
Sequence: MVQGVQLPVCLICGLYSQDIQKHRQGFPSSLKLSNGYILPEGKMTPNTLFVGGIDMKVDENEIREFFAKYGSVKEVKIITYRGGICKGYGFVYFSEDVDIQTIVDQPISFKGKKLKLGPAIMKERSSRSVSSPMIGPSQWVNPTPYMYCSCCPPGLAPPSPVFSGGNQYMQPYSYSSPPGIMVPQVPMNYAQTTYAYQYPLPQWCGEQRTRLVNQNFVDCGVQTLLTLM
What is the function of this protein?
RNA-binding protein involved in gametogenesis in both males and females (PubMed:12296827).  Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and promoting the translation of key transcripts (PubMed:12296827).  Establishes oocyte polarity through interaction with Bucky ball (BUC) (Probable).  Interacts with Bucky ball (BUC) mRNA to mediate Balbiani body formation and oocyte polarity during early oogenesis (By similarity).
What are the official names of this protein?
Deleted in azoospermia-like, DAZ-like protein, zDazl.
What is the protein family that this protein belongs to?
Belongs to the RRM DAZ family.
Protein: PUR9_LACLA
Sequence: MSKRALISVSDKEGIVEFAKEIRELGWEIISTGGTKAVLDQEEIPNIAIDEVTGFPEMMDGRLKTLHPLIHGALLGRRDLESHMKSMTEHHISPIDLVVVNLYPFKETLLAGGSQAEMIEKIDIGGPSMLRSAAKNHASVTVVCDPNDYEKVLTELSVKGETSLSFRQQLAAKVFRHTASYDALIAQYLTEEFPVENVKPEKLTLTYDLKQGMRYGENPQQNADFYESGIPTTYSIAQSKQIHGKELSYNNVRDADAALQIARDFEEPTVVALKHMNPCGIGTATDIEKAWDYAYEADPVSIFGGIIVLNREVTLATAQKMSKIFLEIIIAPSYSKEALEVLSKKKNIRLLTVDFSKKEASEKEALVTGVLGGLLVQNQDVIVENPKEWTVATKVQPTDRQMEAMKFAWKAVKFVKSNGIIVTNDHQTLGVGPGQTNRVGSVKIALEATADKSVELQENAVLGSDAFFPFADNIDEIAKAGIKAIVQPGGSVRDQEVIDACDKYGIAMVFTGLRHFRH
What are the official names of this protein?
Bifunctional purine biosynthesis protein PurH.
What is the protein family that this protein belongs to?
Belongs to the PurH family.
Protein: TRPD_PELPB
Sequence: MPQKKLLQKLLAGEDFSQEEMILCMNNIMDGLFSEMVIAALLALLQKKGVTPTETAGAYYSLMEKAVTIELDENAVDTCGTGGDHAGTFNISTTASIIANSAGVRIAKHGNRSVTSSCGSADVLEALGFTIDLPPEATKELFQESGFAFLFAPLYHPSMKRVAPVRRELGIRTIFNILGPLINPARAKRQLVGVFNRELMELYTEVLLQTGARRAMIVHAMTAEGIALDEPSLNGPTHIVEIHRGTVTEHTVYPEDFGLARHSLSEIQGGERDENARIIRQILDGSAPAAHRDAALFTTAMACYVSGKARCIDDGLDIAREALESGKSEKKFNEILKINAELSRKYRSVVN
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.
Protein: Y2683_SULIA
Sequence: MKIKDAVNMIRWKYREKIDDYVVIIIDRLTENGLKEISFSEIDDVDNNYLYLKSEENTVIPLHRVLMIKRKSDNALIWKR
What are the official names of this protein?
UPF0248 protein M1627_2683.
What is the protein family that this protein belongs to?
Belongs to the UPF0248 family.
Protein: VAS1_CAEEL
Sequence: MRVLFAVFSLIMACQAYDAVLFSNSREIGGTPAAKLVESATAEEPVVFIVNPDFTLGQFSVKANAYTSEPSADYLAKSVKNSNFHESQYFSHQIEATQAQWLSSADQYSAGSPIYIIYGEEWTSMEQLAEQLISKIDNSVGIITSTDAVAHEKSSRVKRVATDEFNSDSENSAAAEANGGFPFPLVIPPYNQTFYSVKPTNGHSCLFYLEGLTVVVEQKKEKVLYYANAYIPGSNFTWAYSETDVTCPNGTIGDFIFKIHLTLENDITGMQGTSKKAFTMKKGDKIDFDLTFTGDLFGYWALNKASASNLAISGYDPYKSASVDGSKVVNGSATQYTKLNSVAGWSLACGQSQAVFFPTNEQSVRIGVALMNTQIQLFNYQNPEKWVESAHFTLQTEDCTGTFSSGSWMGIVSALVLIAGLMFGYVMLQSVQTMDRFDDPKQRQIVINVRE
What is the function of this protein?
Accessory subunit of the proton-transporting vacuolar (V)-ATPase protein pump, which is required for luminal acidification of secretory vesicles (By similarity).  In the germline, required for the trafficking of the receptor RME-2 to the oocyte cell membrane where it regulates the uptake of yolk proteins (PubMed:22768351).  Also, plays an essential role in osmoregulation in the embryo, probably by regulating the proper formation of the eggshell (PubMed:22768351).
What are the official names of this protein?
V-type proton ATPase subunit S1, V-ATPase subunit S1, V-ATPase Ac45 subunit.
What is the protein family that this protein belongs to?
Belongs to the vacuolar ATPase subunit S1 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YBMA_SCHPO
Sequence: MEKASKNKESGVKKANNSFLQNFGVNTAGKENESTSLPRLPKSEDESIPKQSIKSKNKKKTQHFLSDAFESLKRQEIDTNEKEVIVSAPITSKPAQVFYSKKLERKDEGIRKWEKDPFAPISVKSGAWKKPYTKVPEVSINKATSKRTDLINDKPIVIPIPRASTSTLYFGKHNKPTSENRKGPIGIPTEEILTSQNTQAMLHKLFENNVLDNVKDDSMQRQSSFIPGMHIRLLDHQVQGLTWLKSRETVSKSSASGGILADDMGLGKTIQMIALILSHPLPKKKHSIKSTLVVAPLSLIKQWESEVQTKSKLTAIVYHGASRYKLLKVIHEYDVVITTYQILVSEWVSHNTTGTDGKSPTEAKSYEKKKPSLFAFYWWRIILDEAHTIKNKSSKSALACCALQGINRWCLTGTPLQNNVDELYSLVKFLHINPFNDQSVWKDQISLPLCQGEENLVFKRLRMLLSVIMLRRTKTLLEANAGKDGTGGALKLSKRLVYKVICKFEESERDFYSNLARNMERTMSNFVNSGKLGKNYTNILCLLLRLRQACNHPQSLNFQFEQDVDAFNALDGAANTNKLASDQDVDDLANLLETVEIGSRKKSFCTICMAELPPDFHEKKCKDCSRNFKELDKGIQDPNDKTLYKSSKIREILKILSLDEQEEDDTVRGLRKTIIFSQFTTFLDIIDLHLRKAGIGFVRYDGRMNNRAREKSLDLLRSDSGTQVLLCSLKCGALGLNLTCASRVILCDVWWNPAIEEQAIDRVHRIGQRRDVLVYKLVVENTIEEKIVELQNLKRDLAKQALGDGKKSVFTSKKLTLNDLLFLFNKRAAA
What are the official names of this protein?
Uncharacterized ATP-dependent helicase C582.10c.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y3086_VIBC1
Sequence: MFGKGGMGNLMKQAQQMQDRMQKLQEEIANMEVTGESGAGLVKVTITGSHSVRRVEIDESLMEDDKEMLEDLIAAAFNDAARRVEETQKEKMASVTGGMQLPPGMKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein VIBHAR_03086.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: RS5_MYCPN
Sequence: MTDQNQKANQGNGLQTTNLQAHAQRKHNLRPSSEGIKKAVSKKEGGGHNRNNQNRRFQKPAFKSEFEERIVKLKRISKTTKGGRNMRFSVLVVVGNRKGKIGYGIAKALEVPNAIKKAIKAAHNSLHTIEIHKGSIYHEVIGRSGASRVLLKPAPQGTGIIAGGAIRAIIELAGYSDIYTKNLGRNTPINMIHATMDGILKQLSPRRVAILRNKNLNEL
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: VG42_BPMD2
Sequence: MAQANVVLPAPNGKLTEELMGLAIHKLSQLGTIEGDEIGVYTADVPEGRPPGFYFEFRANIIPYLGRR
What are the official names of this protein?
Gene 42 protein, Gp42.