PharMolix/UniProtQA huggingface dataset:
Protein: DABA_AZOC5
Sequence: MLMTTPGSPLPSPDVLLEAANRAARAIPPLWPLASSVAVNPFLGQTGEPLATAASRLRRVAGIPLTMPRSWYADRLRSGEIAEEDLRAAFESAPAALRPKTFASLKRAVQSERPEPHAIPTLADLARDVAGIDWPAIVNDRISHWASSYFDEGQALWAKGQQGAAYSAWRIIATHDLTPEIAGLEGFAQSVADAPANAEDAIIACVARLGLCGPALESYFHRLLTTLGGWSQLARYRLWQAELTGNTDASVTDLLTIRLIWEAALLRKFGPVVEAQWKAAIAAYAEPVSATPEDVVDAILQEAAERAAQWRLGACLTGTSPARVADGRPTLQMAFCIDVRSEVFRRALESLDPGIRTLGFAGFFGLGIGHRRFGSDVVEARLPVLLKPGIFTCSGEATPAVTSSDLAARITARVERAWGRFKLAAISSFAFVEAAGPIYVAKLLRDGLGLKRHAAPNDPAPRPTSALDLDTRLTMAVSILKAMSLTRGFARLVLLAGHGANVVNNPHASALHCGACGGYSGEVNARLLASVLNDREVRADLAERGIIVPEDTLFLAALHDTTTDDVNIYAADHASAAHAEDVDQAERWLKSAGILARGERALRLPRAKQGQDIPHRARDWAELRPEWALAGCQAFIAAPRARTAGHDLAGRAFLHDYDWRRDDGFGVLELILTAPVVVASWISLQYYGSTVAPDVFGAGNKLLHNVTGGIGVVEGNGGLLRAGLPWQSVHDGERLTHEPLRLSVLIEAPREAIARILERHPEVRALFDNLWLHLFALDDKGRMAWRYTGDLQWETCVGDEHADEHSVREVA
What is the function of this protein?
Part of an energy-coupled inorganic carbon pump.
What are the official names of this protein?
Probable inorganic carbon transporter subunit DabA.
What is the protein family that this protein belongs to?
Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: MC1_PINRA
Sequence: MAAPRSSAKSAALFAILLIVAAVQAEDCSNAMDKLAPCTSAVGLSSNGVKPSSECCDALKGTSTSCVCKSVRAVISLPAKCNLPALTCSGSR
What are the official names of this protein?
Male-cone protein 1, PRMC1.
What is the protein family that this protein belongs to?
Belongs to the A9/FIL1 family.
What are the subcellular locations of this protein?
Secreted.
Protein: RL5_MYCAP
Sequence: MNLKQKYLTDVVPALMKQYGYKSIMQVPRLEKIVLNMTAGKEVTNSKAIEEVLNELTQISGQKPFQTRAKKSNASWKLREGMAMGGKVTLRRDRMWDFLEKFINVAMPRIRDFRGANPKAFDGRGNYSFGVKEEIIFPEIEFDKIRRIKGLDVQIITSVNNDKEARSLLELIGMPFSKGEK
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: HPS4_HUMAN
Sequence: MATSTSTEAKSASWWNYFFLYDGSKVKEEGDPTRAGICYFYPSQTLLDQQELLCGQIAGVVRCVSDISDSPPTLVRLRKLKFAIKVDGDYLWVLGCAVELPDVSCKRFLDQLVGFFNFYNGPVSLAYENCSQEELSTEWDTFIEQILKNTSDLHKIFNSLWNLDQTKVEPLLLLKAARILQTCQRSPHILAGCILYKGLIVSTQLPPSLTAKVLLHRTAPQEQRLPTGEDAPQEHGAALPPNVQIIPVFVTKEEAISLHEFPVEQMTRSLASPAGLQDGSAQHHPKGGSTSALKENATGHVESMAWTTPDPTSPDEACPDGRKENGCLSGHDLESIRPAGLHNSARGEVLGLSSSLGKELVFLQEELDLSEIHIPEAQEVEMASGHFAFLHVPVPDGRAPYCKASLSASSSLEPTPPEDTAISSLRPPSAPEMLTQHGAQEQLEDHPGHSSQAPIPRADPLPRRTRRPLLLPRLDPGQRGNKLPTGEQGLDEDVDGVCESHAAPGLECSSGSANCQGAGPSADGISSRLTPAESCMGLVRMNLYTHCVKGLVLSLLAEEPLLGDSAAIEEVYHSSLASLNGLEVHLKETLPRDEAASTSSTYNFTHYDRIQSLLMANLPQVATPQDRRFLQAVSLMHSEFAQLPALYEMTVRNASTAVYACCNPIQETYFQQLAPAARSSGFPNPQDGAFSLSGKAKQKLLKHGVNLL
What is the function of this protein?
Component of the BLOC-3 complex, a complex that acts as a guanine exchange factor (GEF) for RAB32 and RAB38, promotes the exchange of GDP to GTP, converting them from an inactive GDP-bound form into an active GTP-bound form.  The BLOC-3 complex plays an important role in the control of melanin production and melanosome biogenesis and promotes the membrane localization of RAB32 and RAB38 (PubMed:23084991).
What are the official names of this protein?
BLOC-3 complex member HPS4, Hermansky-Pudlak syndrome 4 protein, Light-ear protein homolog.
Protein: PYRG_CAMJE
Sequence: MKQTKYIFVTGGVLSSLGKGIAAASIATLLKNSGLKVSILKADPYINVDPGTMSPFEHGEVFVTDDGAETDLDLGHYERFLDESLSQDNNFTTGRVYQSVIEKERRGEYLGKTIQVIPHIVGEIKDRIKKAGEGKDILIVEIGGTVGDIEGLPFLEAIRALRLEVGKNNAMNIHLTLVPFIKAAGELKTKPTQHSVGELRRIGISPDMIICRSEKALDRDLKDKIAISCGVEKNCVIESVDAASIYQIPLNFLKQDILSPIAEILDLKNLKPNMENWDSLVKRVIAPSNEVKIAFVGKYVDLKESYKSLTEAIIHAGAALDTKVELKWVDSEKLENMESSEVFKDVSGILVAGGFGYRGVEGKIKAIQYARENKIPFLGICLGMQLALVEFARNVLKLKDVNSSEFNEKCQNPVVYLIDEFMDTNGEKQIRTAKTPLGGTMRLGAYKCDIKEKSLLAKVYNEVKSVKERHRHRYEANPKYRADFEKYGLIVSGESKGLIEAVELNCHPFFLAVQFHPEFTSRLEHVNPVICSFIKAAINYEDN
What is the function of this protein?
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.  Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
What are the official names of this protein?
CTP synthase, Cytidine 5'-triphosphate synthase, Cytidine triphosphate synthetase, CTP synthetase, CTPS, UTP--ammonia ligase.
What is the protein family that this protein belongs to?
Belongs to the CTP synthase family.
Protein: RING1_DROME
Sequence: MTSLDPAPNKTWELSLYELQRKPQEVITDSTEIAVSPRSLHSELMCPICLDMLKKTMTTKECLHRFCSDCIVTALRSGNKECPTCRKKLVSKRSLRADPNFDLLISKIYPSREEYEAIQEKVMAKFNQTQSQQALVNSINEGIKLQSQNRPQRFRTKGGGGGGGGGGNGNGAANVAAPPAPGAPTAVGRNASNQMHVHDTASNDSNSNTNSIDRENRDPGHSGTSAASAITSASNAAPSSSANSGASTSATRMQVDDASNPPSVRSTPSPVPSNSSSSKPKRAMSVLTSERSEESESDSQMDCRTEGDSNIDTEGEGNGELGINDEIELVFKPHPTEMSADNQLIRALKENCVRYIKTTANATVDHLSKYLAMRLTLDLGADLPEACRVLNFCIYVAPQPQQLVILNGNQTLHQVNDKFWKVNKPMEMYYSWKKT
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-118' of histone H2A, thereby playing a central role in histone code and gene regulation.  H2A 'Lys-118' ubiquitination gives a specific tag for epigenetic transcriptional repression.  Polycomb group (PcG) protein.  PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development.  PcG proteins are not required to initiate repression, but to maintain it during later stages of development.  PcG complexes act via modification of histones, such as methylation, deacetylation, ubiquitination rendering chromatin heritably changed in its expressibility.  May play a role in meiotic sister chromatid cohesion.
What are the official names of this protein?
E3 ubiquitin-protein ligase RING1, RING-type E3 ubiquitin transferase RING1, Sex comb extra protein, dRING protein, dRING1.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Colocalizes with ubiquitinated histone H2A. Colocalizes with Pc, Pcl, Psc, ph at many sites on polytene chromosomes. Colocalizes with ORD on the chromatin of primary spermatocytes during G2 of meiosis.
Protein: GCS2_ECO8A
Sequence: MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNEITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPHFIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKDYLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKMGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: AACS_RAT
Sequence: MSKLARLEREEIMECQVMWEPDSKKDTQMDRFRAAVGTACGLALGNYDDLYHWSVRSYSDFWAEFWKFSGIVCSRMYDEVVDTSKGIADVPEWFRGSRLNYAENLLRHKENDRVALYVAREGREEIAKVTFEELRQQVALFAAAMRKMGVKKGDRVVGYLPNSAHAVEAMLAAASIGAIWSSTSPDFGVNGVLDRFSQIQPKLIFSVEAVVYNGKEHGHLEKLQRVVKGLPDLQRVVLIPYVLPREKIDISKIPNSMFLDDFLASGTGAQAPQLEFEQLPFSHPLFIMFSSGTTGAPKCMVHSAGGTLIQHLKEHVLHGNMTSSDILLYYTTVGWMMWNWMVSALATGASLVLYDGSPLVPTPNVLWDLVDRIGITILGTGAKWLSVLEEKDMKPMETHNLHTLHTILSTGSPLKAQSYEYVYRCIKSTVLLGSISGGTDIISCFMGQNSSIPVYKGEIQARNLGMAVEAWDEEGKTVWGASGELVCTKPIPCQPTHFWNDENGSKYRKAYFSKYPGVWAHGDYCRINPKTGGIVMLGRSDGTLNPNGVRFGSSEIYNIVEAFDEVEDSLCVPQYNRDGEERVVLFLKMASGHTFQPDLVKHIRDAIRLGLSARHVPSLILETQGIPYTINGKKVEVAVKQVIAGKTVEHRGAFSNPESLDLYRDIPELQDF
What is the function of this protein?
Converts acetoacetate to acetoacetyl-CoA in the cytosol.  Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids.
What are the official names of this protein?
Acetoacetyl-CoA synthetase.
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent AMP-binding enzyme family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: OBG_CLOBL
Sequence: MFIDTAKIFVKSGKGGDGSISFRREKYIAFGGPDGGDGGKGGNVVLVVDPNMTTLLDFTYKRKYKAEPGGNGAGSKCFGKNGKDLHIKVPMGTIVKDAETDKIMADLSKPEDSYVVAKGGRGGKGNCRFTTPTRQAPDFAEPGMPEEERWIKLELKLLADVGLIGFPNVGKSTLLSVVSKARPKIANYHFTTLKPNLGVVSIEGVNNFVIADIPGIIEGASEGVGLGLDFLRHVERTRVLIHVIDISSVEGRDPYDDFLKINDELKRYSVKLYDRPQIIAANKSDMLFDEEKFEEFKTKVEKHGYNKVFKISAATKQGVDDLMKEAARLLSTIPVTDLEISEEDRFIEEEKRFTYSIRKEDNTYIVEGSFVDRLLNAVNVNDPDDLRYFHKVLKNKGVMEELMEMGIEDGDVVRLNDFEFDFLL
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YL342_YEAST
Sequence: MNVFMPIRVFLYSYVIINSLLSSFFHQYRPLFIKNGAAFGVSNSEKICVTLIVNELI
What are the official names of this protein?
Uncharacterized protein YLR342W-A.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ALR_CLOTE
Sequence: MFKHLRPVWAEIDLDKLVYNMQQIKNICKGREIIAVVKADAYGHGALDIAPILLENGATRLAVAVLNEAIELRRGGIDAPIMVLGFTPDSLIETSLKYNIEQTVYSYEIAKEISEVAVKSNRVAKIHIALDTGMGRIGFLPDKESIDKIYKLSKLPNIQIEGIFSHFASADEQDKTYTKLQFNKFLWVCNSLEERGIDIKIRHIANSAAIIDMPELHLEGVRPGIIMYGYYPSSEVNKGKLDLKPVMSLKTTIVHIKNMEKGKYISYGREFKTEKESIIATLPVGYADGYSRSLYDKGGKIILKEQLAPLVGRICMDQCMIDVSHIEDVKIGDEVILMGENKGIKMTAEEIGNLLGTINYEVTCMISKRVPRVYIRDGNIVGIRNYV
What is the function of this protein?
Catalyzes the interconversion of L-alanine and D-alanine.  May also act on other amino acids.
What are the official names of this protein?
Alanine racemase.
What is the protein family that this protein belongs to?
Belongs to the alanine racemase family.
Protein: GLMM_VIBCH
Sequence: MSDKRRYFGTDGVRGKVGQYPITPDFVLKLGWAAGRVLAKQGTRKVIIGKDTRISGYMLESALEAGLAAAGLKATFTGPMPTPAVAYLTQTFRAEAGIVISASHNPYYDNGIKFFSYEGTKLPDDIELAIEAELDKDIECVESAELGKASRMVDAAGRYIEFCKSTFPSKLSLSGLKLVVDCANGATYHIAPNVFRELGAEVIAMGVEPNGLNINDQVGATDVRALQKRVVEEHAHLGLAFDGDGDRIIMVDHLGNKVDGDQIAYIIARDALRRGELKGGVVGTLMTNLGMENGLKQLGIPFVRAAVGDRYVMEKLLEKGWKIGAENSGHVILLDKVTTGDAIVAGLQVLASVVGSEMTLHELAKGMTLYPQVLENVRFAGDNNPLEADAVKAAVSEVEAELGSKGRVLLRKSGTEPLIRVMVEGEDETLVKQSALKIAQAVKDNC
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RIC1_ORYSJ
Sequence: MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDSYLESYISTIGVDFKIRTVEQDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLNEIDRYASENVNKLLVGNKCDLAENRVVSYEAGKALADEIGIPFLETSAKDATNVEKAFMTMAGEIKNRMASQPATNASKPATVQMRGQPVAQQSSCCS
What is the function of this protein?
Possesses GTPase activity.
What are the official names of this protein?
Ras-related protein RIC1.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ATXR6_ARATH
Sequence: MVAVRRRRTQASNPRSEPPQHMSDHDSDSDWDTVCEECSSGKQPAKLLLCDKCDKGFHLFCLRPILVSVPKGSWFCPSCSKHQIPKSFPLIQTKIIDFFRIKRSPDSSQISSSSDSIGKKRKKTSLVMSKKKRRLLPYNPSNDPQRRLEQMASLATALRASNTKFSNELTYVSGKAPRSANQAAFEKGGMQVLSKEGVETLALCKKMMDLGECPPLMVVFDPYEGFTVEADRFIKDWTIITEYVGDVDYLSNREDDYDGDSMMTLLHASDPSQCLVICPDRRSNIARFISGINNHSPEGRKKQNLKCVRFNINGEARVLLVANRDISKGERLYYDYNGYEHEYPTEHFV
What is the function of this protein?
Histone methyltransferase that specifically monomethylates 'Lys-27' of histone H3 (H3K27me1).  Has higher activity on nucleosomes containing H3. 1 than H3. 3.  Involved in the formation of constitutive heterochromatin and the silencing of heterochromatic elements.  May act as a positive regulator of the G1-S transition.  Influences which sets of rRNA gene variants are expressed or silenced.  Up-regulated by E2FB.
What are the official names of this protein?
Histone-lysine N-methyltransferase ATXR6, Protein SET DOMAIN GROUP 34, Trithorax-related protein 6, TRX-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: RL14_CLAM3
Sequence: MIQQESRLKIADNTGAKEILTIRVLGGSGRRYAGLGDVIVATVKDAIPGGNVKKGEVVKAVIVRTKKETRRPDGSYIKFDENAAVILNSNGEPRGTRIFGPVGRELRDKKFMKIISLAPEVI
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NIKD_SHISS
Sequence: MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAATLGILPAGVRQTAGEILADGKAVYPCALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHAVTRSLVSAHLALYGMELAS
What is the function of this protein?
Part of the ABC transporter complex NikABCDE involved in nickel import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Nickel import ATP-binding protein NikD.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PYRF_SHISS
Sequence: MTLTASSSSRAVTNSPVVVALDYHNRDDALSFVDKIDPRDCRLKVGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASGGARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQKCGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYMVIGRPVTQSVDPAQTLKAINASLQRSA
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: CINP_MOUSE
Sequence: MEAKTLGIATPRKPVLSVSARKLKDNAADWHNLILKWDSLSDKGFTTASSIANLKVSLLSKEKVELESSSPASMEEEEKTNLDYDKGLEALCEELQAILDGLTKIQMKMEKLSSTTKGICELENYHYREESSRPPLFHTWPTAFFYEVSRRLSEAYKKELLLKHTIGAELAHTADRNLSLTYLSMWLHQPYIESNSKLQLESMLLETGHRAL
What is the function of this protein?
Component of the DNA replication complex, which interacts with two kinases, CDK2 and CDC7, thereby providing a functional and physical link between CDK2 and CDC7 during firing of the origins of replication.  Regulates ATR-mediated checkpoint signaling in response to DNA damage.  Also involved in the cytoplasmic maturation steps of pre-60S ribosomal particles by promoting the release of shuttling protein RSL24D1/RLP24 from the pre-ribosomal particles.  Promotes maturation of pre-60S ribosome together with SPATA5, SPATA5L1 and C1orf109.
What are the official names of this protein?
Cyclin-dependent kinase 2-interacting protein.
What is the protein family that this protein belongs to?
Belongs to the CINP family.
What are the subcellular locations of this protein?
Nucleus. Note=Binds to nuclear under G1 conditions, and dissociates from chromatin with the start of DNA replication.
Protein: UL56_HHV1E
Sequence: MASEAAQPDAGLWSAGHAFADPPPPYDSLSGRNEGRLSLLIWTPPRTHLHRTLLGPCRPCQFRQPPPERARRRSGAAHALPPSEPLGAPGAAPNDVRSAGVLALAGYWQPPSFFRKPGLWPHPTSQGTSCRASRCTPRLCRTTPQPMPLSWPFVRPNSRPGLWRPTTSDERLTRARGGLLGSIRASCTGPNAARGSYDHAPYRREGCCGVVGRHAVFGVVAIVVVIILVFLWR
What are the official names of this protein?
Protein UL56.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae UL56 family.
Protein: NAGB_SALPK
Sequence: MRLIPLSTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGTPLTAYKALVEMHKAGEVSFKHVVTFNMDEYVGLPKEHPESYHSFMHRNFFDHVDIPAENINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIKTLTHDTRVANSRFFDGDVNQVPKYALTVGVGTLLDAEEVMILVLGHQKAQALQAAVEGNVNHMWTISCLQLHPKAVVVCDEPSTMELKVKTLKYFNELEAENIKGL
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: SYC_LACLA
Sequence: MKIYNTYSRQLEDFQPIEPGKVKMYVCGPTVYNYIHVGNARSVVAFDLVRKYLEFRGFEVQYISNFTDVDDKIINGAKAANMTTTDFSERYIAAFYEDTDALNVKRASQNPKATEFIEAMIEFIQELVDKEFAYVSQGDVYFRVSKSKDYAKLANKNLADLLAGASGRTDEETKLKESPADFALWKSAKADEVSWQAPWGAGRPGWHIECSVMSTSLLGETIDIHGGGADLEFPHHTNEIAQSEAKTGQKFVNYWMHNGFVNVDGEKMSKSLGNFTTVHELLQVVNPQILRFFLATTHYRRPVNFTDDALTEAENNIKKIENAYRHLDEQAESNLSALTTFRNDFVAAMDEDFNIANGMTVFYDFVSWVNKGNGGPEVKEFFDQVLEILGIKFKFEQSLDSEIEAMIEARQLAREVRDFAKSDEIRDALKAQGIVLEDTKDGVRWHRE
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQGF_HELP2
Sequence: MILACDVGLKRIGIAALLNGVVLPLEAILRHNRNQASRDLSDLLREKNIQVLVVGKPNESYADTNVRIEHFIKLVDFTGEIVFINEDNSSIEAYDNLEHLGRKNKRLATKDGRLDSLSACRILERYCQQVLKNH
What is the function of this protein?
Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
What are the official names of this protein?
Putative pre-16S rRNA nuclease.
What is the protein family that this protein belongs to?
Belongs to the YqgF nuclease family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTOX_SALDC
Sequence: MKYDLIIIGSGSVGAAAGYYATRAGLKVLMTDAHMPPHQQGSHHGDTRLIRHAYGEGEKYVPLMLRAQTLWDELSTHNEEPIFVRSGVVNLGPADSAFLANVARSAQQWQLNVERLDATALMTRWPEIRVPDNYIGLFEADSGFLRSELAITTWLRLAREAGCAQLFNSQVSHIHHDDNGVTIETSEGSYHASKALISAGTWVKALVPELPVQPVRKVFAWFKADGRYSTKNRFPAFTGEMPNGDQYYGFPAENDELKIGKHNGGQLIQAPEERKPFAAVASDGAEAFPFLRNVLPGIGGCLHGAACTYDNSPDENFIIDTLPGHENTLVITGLSGHGFKFAPVLGEIAADFALGKTSSFDLTPFRLSRFSQ
What is the function of this protein?
Catalyzes the oxidative demethylation of N-methyl-L-tryptophan.
What are the official names of this protein?
N-methyl-L-tryptophan oxidase, MTOX.
What is the protein family that this protein belongs to?
Belongs to the MSOX/MTOX family. MTOX subfamily.
Protein: COAD_SODGM
Sequence: MTNKAIYPGTFDPLTNGHLDLVTRAAKMFDVVVLAIAASPSKRPLFDLNERVALATQVTAHLPNVKVTGFSDLMADFARQQQANILIRGVRAMTDVDYEMPLAKMNRHLMPALETVFMLPAEAWSYISSTLVKEVALHGGDVDHFLPAPIAKEVRARLHP
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF3_MOUSE
Sequence: MSDWKGYISAVLRDQRIDDVAIVGHSDNRCVWASRPGGLLAAISPQEVGVLTGPDRHTFLQTGLSVAGRRCCVIRDYLLAEGDGVLDARTKGLDGRAICVGHTPRALLVLMGRRGVHGGILNKTVHDLIGGLREQCS
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  Binds to poly-L-proline, phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol 4-phosphate (PtdIns(4)P).  Slightly reduces actin polymerization.  May be involved in spermatogenesis.
What are the official names of this protein?
Profilin-3, Profilin III.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus.
Protein: MFPA_MYCTU
Sequence: MQQWVDCEFTGRDFRDEDLSRLHTERAMFSECDFSGVNLAESQHRGSAFRNCTFERTTLWHSTFAQCSMLGSVFVACRLRPLTLDDVDFTLAVLGGNDLRGLNLTGCRLRETSLVDTDLRKCVLRGADLSGARTTGARLDDADLRGATVDPVLWRTASLVGARVDVDQAVAFAAAHGLCLAGG
What is the function of this protein?
Might be involved in fluoroquinolone resistance (PubMed:15933203).  Inhibits ATP-independent DNA relaxation, ATP-dependent DNA supercoiling and ATP-dependent decatenation by endogenous gyrase, 50% inhibition occurs at 2 uM; inhibition is abolished if GyrA is mutated (Asp-87 to Gly or His) (PubMed:19060136).  Also inhibits fluoroquinolone-promoted dsDNA cleavage (PubMed:19060136).  Increases fluoroquinolone (ciprofloxacin or moxifloxacin) inhibition of gyrase supercoiling activity in a concentration-dependent manner (PubMed:19060136).  Inhibits DNA relaxation and supercoiling by E. coli gyrase (PubMed:15933203).  Forms a structure that exhibits size, shape and electrostatic similarity to B-form DNA; it may bind to DNA gyrase which is postulated to protect it from fluoroquinolones (PubMed:15933203).
What are the official names of this protein?
Pentapeptide repeat protein MfpA, MfpAMt.
What is the protein family that this protein belongs to?
Belongs to the pentapeptide repeat protein family.
Protein: LEUC_ECO55
Sequence: MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRTHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: WNT2_STRPU
Sequence: SGSCTSQVCWNAMPKLRQISEALLKSHIQAYHMMYSKRSLKLRPLQERNRNPSKTDIVYLTPDYCEPNKRHGSLGTHGRRCNKTSTGVNGCRLMCCGRGYQTMLRHVTESCHCRF
What is the function of this protein?
Ligand for members of the frizzled family of seven transmembrane receptors.  Probable developmental protein.  May be a signaling molecule which affects the development of discrete regions of tissues.  Is likely to signal over only few cell diameters.
What are the official names of this protein?
Protein Wnt-2.
What is the protein family that this protein belongs to?
Belongs to the Wnt family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix.
Protein: APT_PROMH
Sequence: MTANAQQLQFIKDSIETIPDYPKEGILFRDITTLLDNPAAYQATIDLLVEHYQGQGITKVVGTEARGFLFGAPVALRLGVGFVPVRKKGKLPRETLSETYDLEYGTDTLEIHKDSITDKDKVLMVDDLLATGGTIEATARLIRRLGGTVTEAAFIICLPDLGGIERLEKEGIHSFTLVNFPGH
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.