PharMolix/UniProtQA huggingface dataset:
Protein: DCC1_DICDI
Sequence: MTPNDDDDTKVITFSSDYPDTDYRFLEANQEILDQIKNNKKLVIKGSLTDEAVLCTDDKTFTIRAGHTSNSMLLVSKDTNKIKVALQYHLELTEIQPKLNVLKDLLYSKAIDNSLDFEDDENLLGFSFDEIIDRIQSSEKEIQQYLLKLNTLIYKNRYIVLSENYEFKILELILSEATIGAWKLDNIPIDKCIENIRAPEFIIKHCLQLYSKQKSPTNSGGGGEEIKGGGGDDNNDENICSLDFNKVCIFRAKQLLTLSNKSNMKFEDFMDNWKDTLPIEIQPNFSMLKGIAILIPSSSTNPKEKSVKFINESILPTIPKARFKELFQISTRWSIDDIEPFIKSTIPPGNSLEQFILTYSRPITTSTGEKMIVTRF
What is the function of this protein?
Loads PCNA onto primed templates regulating velocity, spacing and restart activity of replication forks.  May couple DNA replication to sister chromatid cohesion (By similarity).
What are the official names of this protein?
Probable sister chromatid cohesion protein DCC1.
What is the protein family that this protein belongs to?
Belongs to the DCC1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: THB_LITCT
Sequence: MPSSMSGYIPSYLDKDELCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIAVGMATDLVLDDSKRLAKRKLIEENREKRRKDELQKTLVQKPEPTPEEWELIQVVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSQFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGVSLSSFNLDDTEVALLQAVLLMSSDRPGLSSVERIEKCQEGFLLAFEHYINYRKHNVAHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED
What is the function of this protein?
Nuclear hormone receptor that can act as a repressor or activator of transcription.  High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
What are the official names of this protein?
Thyroid hormone receptor beta, Nuclear receptor subfamily 1 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family. NR1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: SFT2C_HUMAN
Sequence: MADLHRQLQEYLAQGKAGGPAAAEPLLAAEKAEEPGDRPAEEWLGRAGLRWTWARSPAESAAAGLTCLPSVTRGQRLAAGGGCLLLAALCFGLAALYAPVLLLRARKFALLWSLGSALALAGSALLRGGAACGRLLRCEEAPSRPALLYMAALGATLFAALGLRSTLLTVLGAGAQVAALLAALVGLLPWGGGTALRLALGRLGRGAGLAKVLPV
What is the function of this protein?
May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
What are the official names of this protein?
Vesicle transport protein SFT2C, SFT2 domain-containing protein 3.
What is the protein family that this protein belongs to?
Belongs to the SFT2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PNG6_ASFB7
Sequence: MDCWTIREKNYSYIILSILVILLIWYLILNYCRSKKNAVTNNMPPPAYTVSSSCSQ
What are the official names of this protein?
Uncharacterized membrane protein pNG6.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: PSII_DICDI
Sequence: MKIIFNLLILFSLVNFINSQSTTQATTLKLEGTIYDQYPYYDNNFEPIAGSLTTRLVQNAINTTTRTPTLNTLLPFTTTNVMGRMVTPSLFQYFYQPNKNAPLTNNSGANFPIPMTVNLTLNPSTGTYVYDNQFFFPIDYQGFDTNPFYRNYTDGTDYHNFHFCLKINTRFTYTGNEVFYFVGDDDVWVFINDQLVIDLGGLHEAAGKNIDLTTLGLTKNKDYTFDFFYCERHTTKSTIRIETSIQAYCPFYDYCGVCYGDGSTCCDPVVNCNDGDLCTIDSCPPRDTIIPAGFSISDLCQHAPVSCPSIDMCTNNTCDSKSGQCTPTSIKCDDKSSQCLTLKPCDPSSGCLYTSSCTSAHNPCNTGACSNGQCQTKSNSTCAAELGNDPCKVYYCDINSGCVSQPLCKQGPDSCEQNVCNAGVCTIKKLDPSVCSCGCVLNKCQKNNCVTASNGTSVCSPLPLDEIDDGNPCTDDHCDETTGLITHNITTKCTGCMKCNTTTGSCSPTNNECQDGNECTDNICVAAATNINQGECSNKTVSCPTTDKCLVYTCDTNKGCVSKPVVCPNSGNCQVGVCDSVKGCTLVPRVCNSTAFCLVSQCDEAIGCITFEKRCSPDNSKCQSGVCVNATATEPGKCKSVDYDPKPFICQTGAIVSTAVVASVVVVGAVVLGAAIFAGKKGYDHWKANQGQVFASSNANPLYQQSNNGGENALFEAPQ
What are the official names of this protein?
Protein psiI.
What is the protein family that this protein belongs to?
Belongs to the prespore-cell-inducing factor family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: RECR_LACP3
Sequence: MQYPEPISKLIDSYMRLPGIGAKTATRLAFYTIDMNKDDVTAFAKSLVAAKEDLHYCSICGNITDEDPCAICRDKSRDQSTILVVEQPKDVMSIDRAQDYHGLYHVLHGVLSPIEGRGPEDLNIESLLKRLKANKAVKEVIIATNATPEGEATAQYLARLIKPAGIKVTRLAHGLSVGSDIEYADEMTLMKAVEGRTEL
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SYY_RICCN
Sequence: MRFIEEFINKGYFHQCTDLDRLTAITKETKIAAYIGFDCTATSLHIGSLMQIMILRLLQQHGHKPIVIIGGGTSKIGDPTWKDEVRKILSKEDIAKNAEGIKKSLSKFIKFGDGKSDAIMLDNAEWLDSFNYLDFLRDFGSYFSVNRMLTMDSVKLRLEREQHLSFLEFNYMLLQAYDFYYLSKHYNCSLQLGGSDQWGNIVMGADLIRKISGKEVFGMTTPLLTTSSGAKMGKTAAGAVWLNEDLLSPYDYYQYWRNCEDADIVRFAKLYSEFTQEELNRFESLAAEDINAAKKQLAYELTKLCHSEQAAKSALETAVKIFEEGQIDENLPTVVLEQEVLQAGISAYELFHEAGLATSKSEARKLIRGNGAKINDRLVEDENMIINTNFLLDKKVIKLSAGKKKHILVRV
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRMD_BACP2
Sequence: MKIDFLTLFPEMFEGVLHSSILKKAQEKEAVSFNVVNFREYSDHKHKTVDDYPYGGGAGMVLKAQPVFDAVEDLTNKASKKPRIILVCPQGERYTQKKAEELAKEEHLMFICGHYEGYDERIREHLVTDEISIGDFVLTGGELPAMMIADSVVRLLPHVLGKEASHIEDSFSTGLLEHPHYTRPADYKGLKVPDVLLSGNHAKIEEWRRKESLKRTYTRRPDLIDSCKTLTEEEKRWLWQLHND
What is the function of this protein?
Specifically methylates guanosine-37 in various tRNAs.
What are the official names of this protein?
tRNA (guanine-N(1)-)-methyltransferase, M1G-methyltransferase, tRNA [GM37] methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNA methyltransferase TrmD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL35_BORAP
Sequence: MANKMKTRKSAKKRYSFTVNGKVKYKKQNLRHILTKKSSKRKRNLRKSGNLSCFEVKRIKTLLPYD
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: RL5_PARUW
Sequence: MSRLKKRYLADVKPELQKKFAYKNLMQVPGLVKVVINMGIAEASKDKNSIQDCVKEMTMLSGQKPVITKAKKAISNFKLREDQPIGVKVTLRGQRMFDFIDRFVNIVCPRIRDFRGFPSKCDGMGNYTLGLDDQQIFPEINLDEVKRTQGMHITFVTSAKTDEECVELLRLLGIPFKNLPISVAA
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: ENOPH_SCLS1
Sequence: MEAKPRVKVVLLDIEGTVCPISFVKDVLFPYALAALPETLSTEWDSSSFLPYRSAFPPEHSSTPEALLSHVRDLMAQDLKIPYLKSLQGYLWLRGYESGTLKCPLFPDVYPAMKKWKENGAKICIYSSGSVAAQKLLWRYTAEGDLRGCIWNGVDGAEEIEGGYWDTVNAGLKQESTSYEKIAKANRALGEVGEWLFLSDNVKEVRAAKESGMKSFVVVREGNADVSVEEKNRQVLITSFREVEAMVEVTGESA
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: KTHY_SYNSC
Sequence: MTGRFIVLEGIDGCGKTTQIQHLLEWLPNSGLMPKGAAVVCTREPGGTPLGRSIRELLLHTSDQEAPAPTAELMLYAADRAQHVETLIRPALERGDWVISDRFSGSTLAYQGYGRGLDRDLIQRLEQIATAGLQPDITLWLRLSVQESLQRRLGDKEDRIEAEGAAFLERVAQGFAQLAEHRSWCAVAADQSASAVRAALERQLQEHLA
What is the function of this protein?
Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.
What are the official names of this protein?
Thymidylate kinase, dTMP kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate kinase family.
Protein: DNAA_BACMK
Sequence: MENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEDIDLPSVKQKHAHDESNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDMNADLAAEALKNIIPNSIPRIISISDIQKAVGGVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKHVEEVKDILK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATF_LACTC
Sequence: MLKVSARHAPVLRLPRRFYAQKTRVVIGPRLKNLDEIKEYLGKPTWSVEKYLQSSSNGETQPPSRETVEKLLKLSGLPNENVEMFQATLGKQLAFINKVQSLPVDESLDPSHARIIDRNSEALDYESLSCSVEQQETEKDSKMGEVGGSWDGTGLAAISENGFYVLREGLLKNRK
What is the function of this protein?
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria.  The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).  Required for proper protein synthesis within the mitochondrion.
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial, Glu-AdT subunit F.
What is the protein family that this protein belongs to?
Belongs to the GatF family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: RS15_PROM5
Sequence: MTLDTAEKQKLIESHQVHPTDTGSVEIQVAMISERITKLSEHLQGNIHDYASRQGLLKMIGKRKRLLSYIKGKDPKNYQDLIKKIGIRG
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: PGK_CHLTA
Sequence: MDKLSIRDLSLEGKKVLVRVDFNVPIKDGKILDDVRIRSAMPTIHYLLKQDAAVILVSHLGRPKGGVFEEAYSLAPIVPVLEGYLGHHVPLSPDCIGEVARQAVAQLSPGRVLLLENVRFHKGEEHPDEDPSFAIELAAYADFYVNDAFGTSHRKHASVYRVPQLFPDRAAAGFLMEKELEFLGQHLLVEPKRPFTAILGGAKMSSKIGVIEALLSCVDHLVLAGGMGYTFLRAINRQVGNSLVEESGIPLAKKVLEKAQALGVKIHLPVDAKVAKQCDSGEDWRELSIQEGIPEGLAGFDIGAQTIELFSKVIQESATIFWNGPVGVYEVPPFDQGSKAIAQCLASHSSAVTVVGGGDAAAVVALAGCASQISHVSTGGGASLEFLEKSSLPGTEILSPAQS
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ITAV_BOVIN
Sequence: MAFPPRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVESPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSHRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSKNIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPKVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSSLHNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQKASGDFQTIKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRPTGLNAVPSQILEGKWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAVLYRARPVITVNAGLEVYPSILNQENKTCPLPGTDLKVSCFNVRFCLKADGKGALPTKLDFQVELLLDKLKQKGAIRRALFLHNRSPGHSKNMTISRGGQMQCEELIAYLRDESEFRDKLTPITIFMEYWLDYRTAADATGLQPILNQFTPANVSRQAHILLDCGEDNVCKPKLEVSVDSDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNSEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSYKVDLAVLAAVEIRGVSSPDHIFLPIPNWKYKENPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNNNTLLYILQYDIDGPMNCTSDMEINPLRIKISNSQTSEKNDTVGGQGDRNHLITKRDLTLNEGDVHTLGCGIAECLKIVCQVGRLDRGKSAILYVRSLLWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDIFNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENGEGNSET
What is the function of this protein?
The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, TGFB1 and vWF.  They recognize the sequence R-G-D in a wide array of ligands.  Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing (By similarity).  ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling.  ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling.  ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling.  ITGAV:ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling.  ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling.  ITGAV:ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.  ITGAV:ITGB3 binds to IL1B and this binding is essential for IL1B signaling.  ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.  ITGAV:ITGB3 and ITGAV:ITGB6 act as receptors for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (By similarity).  Integrin alpha-V/beta-6 or alpha-V/beta-8 (ITGAV:ITGB6 or ITGAV:ITGB8) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity).  ITGAV:ITGB3 acts as a receptor for CD40LG (By similarity).
What are the official names of this protein?
Integrin alpha-V, Vitronectin receptor subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the integrin alpha chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell junction, focal adhesion.
Protein: RK32_ANGEV
Sequence: MAVPKKRTSKSKKRIRKSVWREKTKKIASKAFSLAQSILTNRSKSFYYTTNEKISESTE
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: MAGT1_HUMAN
Sequence: MAARWRFWCVSVTMVVALLIVCDVPSASAQRKKEMVLSEKVSQLMEWTNKRPVIRMNGDKFRRLVKAPPRNYSVIVMFTALQLHRQCVVCKQADEEFQILANSWRYSSAFTNRIFFAMVDFDEGSDVFQMLNMNSAPTFINFPAKGKPKRGDTYELQVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNKTGWAFAALCFVLAMTSGQMWNHIRGPPYAHKNPHTGHVNYIHGSSQAQFVAETHIVLLFNGGVTLGMVLLCEAATSDMDIGKRKIMCVAGIGLVVLFFSWMLSIFRSKYHGYPYSFLMS
What is the function of this protein?
May be involved in Mg(2+) transport in epithelial cells.
What are the official names of this protein?
Magnesium transporter protein 1, MagT1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1, Oligosaccharyl transferase subunit MAGT1, Implantation-associated protein, IAP.
What is the protein family that this protein belongs to?
Belongs to the OST3/OST6 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: LUBX_LEGPH
Sequence: MGYRIEMATRNPFDIDHKSKYLREAALEANLSHPETTPTMLTCPIDSGFLKDPVITPEGFVYNKSSILKWLETKKEDPQSRKPLTAKDLQPFPELLIIVNRFVETQTNYEKLKNRLVQNARVAARQKEYTEIPDIFLCPISKTLIKTPVITAQGKVYDQEALSNFLIATGNKDETGKKLSIDDVVVFDELYQQIKVYNFYRKREMQKNQIQPSVSSGFGFFSLNFLTSWLWGTEEKKEKTSSDMTY
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway.  Acts in conjunction with host E2 ubiquitin-conjugating enzymes UBE2D1 (UBCH5A) or UBE2D3 (UBCH5C), and mediates polyubiquitination of host kinase CLK1.
What are the official names of this protein?
E3 ubiquitin-protein ligase LubX, Legionella U-box protein, RING-type E3 ubiquitin transferase LubX.
What are the subcellular locations of this protein?
Secreted. Host cell. Note=Secreted via type IV secretion system (T4SS), and delivered into the host cell.
Protein: RISB_ECOLC
Sequence: MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: PSB4_ARATH
Sequence: MTTFSVPIDNGDSMKIAEEESQRTLYPYVTGTSIVAIKYKDGVLMASDMGGSYGSTLRYKNIERVKAIGKHSLLGASGEISDFQEILRYLDELTLNDNMWDDGNSLGPKEIHNYLTRVMYNRRNKFNPLWNTLVLGGVKNGKSYLGMVSMIGVSFEDDHVATGFGNHLARPILRDEWHADLSFEDGVKLLEKCMRVLLYRDRSAINKLQIAKITEEGVTVSQPYSLKTYWEFSSFHNPTAGAAGSW
What is the function of this protein?
Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.  The proteasome has an ATP-dependent proteolytic activity.
What are the official names of this protein?
Proteasome subunit beta type-4, 20S proteasome beta subunit G-1, Proteasome component H, Proteasome subunit beta type-7.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: COBT_XANAC
Sequence: MRSDWIFGACAVPDARMRSAALARQEQLTKPPGALGRLEHLAVQLAAWQRTERPGAQRVWIAVYAADHGVAAEGVSAFPQAVTGEMVRNFARGGAAIAVLARELGARLEVVNLGVVNDPGDLPRVRRAWIAPSSANICEQPAMTATQLRDAIAAGADSIAQARSCDTQLFVGGEMGIGNTTSAAALACALLSQFPQAMAGAGTGLDAEGIAHKATVITRALALHADASSPLERLRRLGGFEIAALVGAYIAAAQAGIPVLVDGFITTAAALVATRLNPGVREWLLFGHRSQERGHAALLRALDAEPLLQLDLRLGEASGAAVAIPLLRSACALHNGMATFAEAGVSDA
What is the function of this protein?
Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
What are the official names of this protein?
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, NN:DBI PRT, N(1)-alpha-phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CobT family.
Protein: PEBPH_CAEEL
Sequence: MVVLVTRSLLPALFFASRAPFAAATTSARFQRGLATMAAEAFTKHEVIPDVLASNPPSKVVSVKFNSGVEANLGNVLTPTQVKDTPEVKWDAEPGALYTLIKTDPDAPSRKEPTYREWHHWLVVNIPGNDIAKGDTLSEYIGAGPPPKTGLHRYVYLIYKQSGRIEDAEHGRLTNTSGDKRGGWKAADFVAKHKLGAPVFGNLFQAEYDDYVPILNKQLGA
What are the official names of this protein?
Phosphatidylethanolamine-binding protein homolog F40A3.3.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylethanolamine-binding protein family.
Protein: CALM1_BRAFL
Sequence: MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGFISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVTMMTSK
What is the function of this protein?
Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+).  Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
What are the official names of this protein?
Calmodulin-1, CaM 1.
What is the protein family that this protein belongs to?
Belongs to the calmodulin family.
Protein: GPAA_ASPFC
Sequence: MGCGMSTEDKEGKARNEEIENQLKRDKMMQRNEIKMLLLGAGESGKSTILKQMKLIHEGGYSRDERESFKEIIYSNTVQSMRVILEAMESLELPLEDARNEYHVQTIFMQPAQIEGDSLPPEVGNAIGALWRDTGVQECFKRSREYQLNDSAKYYFDAIDRIAQPDYLPTDQDVLRSRVKTTGITETTFIIGDLTYRMFDVGGQRSERKKWIHCFENVTTILFLVAISEYDQLLFEDETVNRMQEALTLFDSICNSRWFVKTSIILFLNKIDRFKEKLPVSPMKNYFPDYEGGADYAAACDYILNRFVSLNQAEQKQIYTHFTCATDTTQIRFVMAAVNDIIIQENLRLCGLI
What is the function of this protein?
G-protein complex alpha subunit that plays a role in conidiation and regulation of the biosynthesis of secondary metabolites such as dihydroxynaphthalene (DHN)-melanin, via interaction with the G protein-coupled receptor gprM.
What are the official names of this protein?
G-protein complex alpha subunit gpaA, Guanine nucleotide-binding protein subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the G-alpha family. G(q) subfamily.
Protein: RPOB_SORBI
Sequence: MLRNGNEGMSTIPGFSQIQFEGFCRFINQGLAEELEKFPTIKDPDHEIAFQLFAKGYQLLEPSIKERNAVYESLTYSSELYVSARLIFGFDVQKQTISIGNIPIMNSLGTFIINGIYRIVINQILLSPGIYYRSELDHKGISIYTGTIISDWGGRSELAIDKKERIWARVSRKQKISILVLSSAMGSNLREILDNVSYPEIFLSFPNAKEKKRIESKEKAILEFYQQFACVGGDLVFSESLCEELQKKFFQQKCELGRVGRRNMNRRLNLDIPQNNTFLLPRDVLAATDHLIGMKFGTGILDDDDMNHLKNKRIRSVADLLQDQFGLALGRLQHAVQKTIRRVFIRQSKPTPQTLVTPTSTSILLITTYETFFGTYPLAQVFDQTNPLTQTVHGRKVSCLGPGGLTGRTASFRSRDIHPSHYGRICPIDTSEGINVGLTGSLAIHARIDHWWGSIESPFYEISEKAKEKKERQVVYLSPNRDEYYMIAAGNSLSLNQGIQEEQVVPARYRQEFLTIAWEQIHVRSIFPFQYFSIGGSLIPFIEHNDANRALMSSNMQRQAVPLSRSEKCIVGTGLERQTALDSRVSVIAEREGKIISSDSHKILLSSSGKTISIPLVAHRRSNKNTCMHQKPRVPRGKSIKKGQILAEGAATVGGELALGKNVLVAYMPWEGYNFEDAVLISERLVYEDIYTSFHIRKYEIQTDTTSQGSAEKITKQIPHLEEHLLRNLDRNGVVRLGSWVETGDILVGKLTPQIASESSYIAEAGLLRAIFGLEVSTSKETSLKLPIGGRGRVIDVKWIQRDPFDIMVRVYILQKREIKVGDKVAGRHGNKGIISKILPRQDMPYLQDGTPVDMVFNPLGVPSRMNVGQIFESSLGLAGDLLKKHYRIAPFDERYEQEASRKLVFSELYEASKQTKNPWVFEPEYPGKSRIFDGRTGDPFEQPVLIGKSYILKLIHQVDEKIHGRSTGPYSLVTQQPVRGRAKQGGQRIGEMEVWALEGFGVAHILQEILTYKSDHLIARQEILNATIWGKRVPNHEDPPESFRVLVRELRSLALELNHFLVSEKNFRVNREDV
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, PEP, Plastid-encoded RNA polymerase subunit beta, RNA polymerase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACMSD_HUMAN
Sequence: MKIDIHSHILPKEWPDLKKRFGYGGWVQLQHHSKGEAKLLKDGKVFRVVRENCWDPEVRIREMDQKGVTVQALSTVPVMFSYWAKPEDTLNLCQLLNNDLASTVVSYPRRFVGLGTLPMQAPELAVKEMERCVKELGFPGVQIGTHVNEWDLNAQELFPVYAAAERLKCSLFVHPWDMQMDGRMAKYWLPWLVGMPAETTIAICSMIMGGVFEKFPKLKVCFAHGGGAFPFTVGRISHGFSMRPDLCAQDNPMNPKKYLGSFYTDALVHDPLSLKLLTDVIGKDKVILGTDYPFPLGELEPGKLIESMEEFDEETKNKLKAGNALAFLGLERKQFE
What is the function of this protein?
Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS).  ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders.  In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite.  ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
What are the official names of this protein?
2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, Picolinate carboxylase.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.