PharMolix/UniProtQA huggingface dataset:
Protein: LGUL_BRAOG
Sequence: MAENADLVEWPKKDKRRFLHVVYRVGDLDRTIQFYTECFGMKVLRKRDVPEEKYSNAFLGFGPETSNFVVELTYNYGVSSYDIGTGFGHFAISTQDVSKMVEAVRAKGGNVTREPGPVKGGGSVIAFVKDPDGYTFELIQRGPTPEPLCQVMLRVGDLDRAVKFMEKALGMRLLRRIERPEYNTIGMMGYAEEYESIVLELTYNYGVTEYTKGNAYAQIAIGTDDVYKSAEVVKIVNQELGGKITREAGPLPGLGTKIVSFLDPDGWKQVLVDNEDFLKELE
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
What are the official names of this protein?
Putative lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: H43_MAIZE
Sequence: MSGRGKGGKGLGKGARKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVRKIFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H4.3, HM4.
What is the protein family that this protein belongs to?
Belongs to the histone H4 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: LYSC_SYRRE
Sequence: KVYGRCELAAAMKRLGLDNYRGYSLGNWVCAAKFESNFNTHATNRNTDGSTDYGILQINSRWWCNDGRTPGSRNLCHISCSALLSSDITASVNCAKKIVSDRNGMNAWVAWRNRCKGTDVNAWIRGCRL
What is the function of this protein?
Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
What are the official names of this protein?
Lysozyme C, 1,4-beta-N-acetylmuramidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MENC_SHIB3
Sequence: MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALRLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: NDUF6_BOVIN
Sequence: MAASTLGSAWGPLRLGVPGLCRRRPPRGLWARARRLSEPVASGRSVAAGSGLGASGTDRYCLELLRKRDYEGYLCSLLLPAESRSSAFALRAFNVELAQIKDSVSEKTIGLMRMQFWKKTVDDIYSDNPPHQPVAIELWKAVRRHNLTKRWLMKIIDEREKNLDDKAYRNIQELENYAENTQSSLLYLTLEILGIKDLHADHAASHIGKAQGIVTCLRATPYHGSRRRVFLPMDICMLHGVSQEDFLRKSQDRNVRDVVYDVASQAHLHLKHARSFHRSIPVKAFPAFLQTVALEDYLKKIQQVDFDLFHPSLQRKNTLLPLSLYIQSWRKRY
What is the function of this protein?
Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages.  May play a role in the biogenesis of complex I subunit MT-ND1.
What are the official names of this protein?
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6.
What is the protein family that this protein belongs to?
Belongs to the NDUFAF6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Note=Peripherally localized on the matrix face of the mitochondrial inner membrane.
Protein: SYW_NOSS1
Sequence: MGKQRVLSGVQPTGNLHLGNYLGAIRNWVEIQDQYDNFFCVVDLHAITVPHNPATLAADTYAIAALYLACGIDLKYSNIFVQSHVSAHSELAWFLNCITPLNWLQDMIQFKEKAVKQGENVGAGLLIYPVLMAADILLYQADKVPVGEDQKQHLELTRDIVNRFNHQFAKDKPVMKLPEPLIRKEGARVMSLTDGTRKMSKSDPSELSRINLLDPPDQIANKIKRCKTDPVKGLTFDDPERPECNNLLTLYMLLSGKKKEEVAAECQDMGWGQFKPLFTETAINALKPIQEKYQEITADKGYLESVLRDGREKAETVANQTLADVKAALGYSAPV
What is the function of this protein?
Catalyzes the attachment of tryptophan to tRNA(Trp).
What are the official names of this protein?
Tryptophan--tRNA ligase, Tryptophanyl-tRNA synthetase, TrpRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1564_METJA
Sequence: MEVIIKAKVKPTEDKYKVKKAILNIFPKAKLTFIEKDNEFGEWEGKTKSVEKLKELLRSQSILDAARMVLEKGMTENATKFYLNKQAAYVGAVNFDIDTHGGIFVKILADENEDIMKIIKDIAPRTKGGVIINEDELEEEEEKEDSEEIKEGHKEENNLKIKVIDNSSGD
What are the official names of this protein?
UPF0201 protein MJ1564.
What is the protein family that this protein belongs to?
Belongs to the UPF0201 family.
Protein: O164_CONLE
Sequence: MKLTCMMLVAVLFLTAWTFVTANVSRNGLENLFPEERHEMMNPNAAKLNNRDCVKAGTACGFPKPEPACCSSWCIFVCT
What are the official names of this protein?
Conotoxin Leo-O4.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O1 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DDL_CERS1
Sequence: MAGQSGRTFPRVAVLMGGASTEREVSLSSGHSCSAALRDAGYEVTEVDAGPDLARVLAELSPDAVFNALHGRWGEDGCVQGLLEWLRIPYTHSGVLASALAMDKARAKEVFAAAGLPVTQSVLATPEEVRARHILPPPYVVKPNAEGSSVGVYIVHEDANGPPQLAADMPQDLMVETYVPGRELTVTVMGDRVLAVTDILSDGWYDYDAKYRPGGSRHIVPADLPAEITEACHDIALRAHRALGCRGISRSDLRWDEARGLAGLILLETNTQPGMTPTSLSPEQAAHCGYSFPEFCAWLVEDASCSR
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
D-alanine--D-alanine ligase, D-Ala-D-Ala ligase, D-alanylalanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the D-alanine--D-alanine ligase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EX7L_CARHZ
Sequence: MALFIVTVSELTDYIAEKFEKDDWLNQVAVEGELSNCKFSQGHLYFTLKDERAELKGVMYKGRASALPFIPQDGQKVIVFGQVAVYKKRGIYQIYAEMIEPLGIGALYLKFEQTKEKLRDKGYFAEERKKKLPRYPEKIGIVTSKNGAAIRDILTTIKKRWPKATLYLVPVAVQGDEAPGQIVKALNLLNRYKLCEVIILARGGGSFEELAAFNEETVADAIYASNIPVVTGIGHETDTSIADMVADRRAPTPTGAAVEATPNLVEIWNNLREQRQKMVKALANYFQREQKNLEFQERRILRAYEKLITDKSREVTEGLERLLRSFKTTFQQEKNRLSLLKEKLILLSPYLRHKQQKEKLEELKERLFLRCAELLKRNQAVLIQQSLRLRTSVKNLVLQKNLVLSSYEERLKLLNPLKILNRGYAVVFDFEGRVVTSVNNLPERFKIKFSDGEALAKALGKNIIEGDKNDDL
What is the function of this protein?
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
What are the official names of this protein?
Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease VII large subunit, Exonuclease VII large subunit.
What is the protein family that this protein belongs to?
Belongs to the XseA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CHBG_YERPP
Sequence: MEKLLIVNADDFGLCKGQNYGIIDAFRNGVVSSTTAMMNSVDINHAAELSAQYPALPVGMHFVLTFGRPLTAMPSLTDANGELGKWLWQRAGAGTLDLNEIAQELECQFERFSAVFGRPPTHIDSHHHVHMLPQIYPLVAAFAREKSLPLRIDRHEVQQHGLTLDNPRSSEWFNAGFYGENLSEPSFLQLLEHADQQGVNSLEIMCHPAFIDQTLMTSGYCYPRLTELAILTSPTLKPAIAQRGYRLGSFLDC
What is the function of this protein?
Involved in the degradation of chitin.  ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose.  Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF.  Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the inducer of ChbR and the substrate of ChbF.
What are the official names of this protein?
Chitooligosaccharide deacetylase, COD, Chitin disaccharide deacetylase, Chitobiose deacetylase, Chitobiose-6P deacetylase, Chitotriose deacetylase, Chitotriose-6P deacetylase.
What is the protein family that this protein belongs to?
Belongs to the YdjC deacetylase family. ChbG subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACKA_CLOAB
Sequence: MKNLVINCGSSSIKYQFIDMKDETVLAKGLVERIGIKGSVITHKVNGEKYVTETPMEDHKKAIKLVLDALLNDEYGVIKNIDEISAVGHRIVHGGEKYANSVLIDEDVMKSIEDCVSLAPLHNPPHIIGINACKELMPNVPMVAVFDTAFHQTIPDYAYMYAIPYEYYDKYKIRKYGFHGTSHKYVSRTAAEFIGKKVEDLKMVVCHMGNGASITAVENGKSVDTSMGFTPLGGLAMGTRSGDMDPAVVTFLMDKLNINASEVNNLLNKKSGIEGLSGISSDMRDIKKGNYVDKDPKAMLAYSVFNYKIKQFIGSYTAVMNGLDCLVFTGGIGENSFENRREICKNMDYLGIKIDDKKNDETMGIPMDISAEGSKVRVLVIPTNEELMIARDTKDIVGKLK
What is the function of this protein?
Catalyzes the formation of acetyl phosphate from acetate and ATP.  Can also catalyze the reverse reaction.
What are the official names of this protein?
Acetate kinase, Acetokinase.
What is the protein family that this protein belongs to?
Belongs to the acetokinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IL4_RAT
Sequence: MGLSPHLAVTLFCFLICTGNGIHGCNDSPLREIINTLNQVTEKGTPCTEMFVPDVLTATRNTTENELICRASRVLRKFYFPRDVPPCLKNKSGVLGELRKLCRGVSGLNSLRSCTVNESTLTTLKDFLESLKSILRGKYLQSCTSMS
What is the function of this protein?
Participates in at least several B-cell activation processes as well as of other cell types.  It is a costimulator of DNA-synthesis.  It induces the expression of class II MHC molecules on resting B-cells.  It enhances both secretion and cell surface expression of IgE and IgG1.  It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.  Positively regulates IL31RA expression in macrophages.  Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
What are the official names of this protein?
Interleukin-4, IL-4, B-cell IGG differentiation factor, B-cell growth factor 1, B-cell stimulatory factor 1, BSF-1, Lymphocyte stimulatory factor 1.
What is the protein family that this protein belongs to?
Belongs to the IL-4/IL-13 family.
What are the subcellular locations of this protein?
Secreted.
Protein: NAGB_STRSY
Sequence: MKIHVVNNQVEGATVALDILREKLNGGTKVLGLATGSSPLEFYRLIRESDLDFSDVTSVNLDEYVGLGEESDQSYIHFMKENLFNTKPFKQSYLPNGLATDVVAETERYNKILAEHPVDFQILGIGRNGHIGFNEPGAPFDGQTHLVELAPSTIEANARFFDNPEDVPKQAISMGIANIMAAKTIVLMAYGQEKADAIKATVEGAVTEDVPASVLQNHDNVILILDQAAASKLV
What is the function of this protein?
Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
What are the official names of this protein?
Glucosamine-6-phosphate deaminase, GlcN6P deaminase, GNPDA, Glucosamine-6-phosphate isomerase.
What is the protein family that this protein belongs to?
Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
Protein: AAEB_PECAS
Sequence: MKTSSLTGSLFFTTPKFARLRFAFKLSFAIVLSLFLGFHLQLETPRWSVLTAAIVAAGPAFAAGGEPFSGAIRHRGMLRIIGTFIGCIGALVIIIATVRAPVVMLMLCCIWAGLCTWVSSLVKVENAYIFGLAGYTALIIIVSTQGTPLLTPQFAVERCSEIVLGIVCAILADLLFSPRSIKQDVDRSIGELLVDQYRLLQLSMSGTEKEAIDAAWHALVRKTTALSGMRSSLMLESSRWQNSNRRLTSLHTQSLMMITQACETYLILQDVPTPVKSSLKMVLDQPVESLRDVHCRVKALRHLIAADSRDVPPTLIDWVGAATRYLLLAKGVQANGRLNTIEADVLNSDVEIKAPSAETHHAMINGLRTGVATALGCLFWLSTGWTSGSVCMVMIAVVTSLAMRLPNPQMMAKDFLFGTIYALPLGALMFMFIMPSTQQSMLLLCLSLGGMAFFLGLEVQKRRLGSLGALASTINILVLDNPMTFNVSQFLDSAIGQIIGCFLALMVIMLIRDNTKAHTGRTLLNRFVYGAVSALTTNRARRKENHLPALYQQLFLLLNRFPDDIAKYRLALWLIIMHQRLRTLDIPQNAALSAFHRQIRATAEQVISARRDATRSRYFAQLLDELERYQQMLTEQQLPPSVTAPVGRLTGILRDYQHALSN
What is the function of this protein?
Forms an efflux pump with AaeA.  Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell.
What are the official names of this protein?
p-hydroxybenzoic acid efflux pump subunit AaeB, pHBA efflux pump protein B.
What is the protein family that this protein belongs to?
Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: KIF4A_HUMAN
Sequence: MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALKYLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEWKPTKLVKVSRKNIQGCSCKGWCGNKQCGCRKQKSDCGVDCCCDPTKCRNRQQGKDSLGTVERTQDSEGSFKLEDPTEVTPGLSFFNPVCATPNSKILKEMCDVEQVLSKKTPPAPSPFDLPELKHVATEYQENKAPGKKKKRALASNTSFFSGCSPIEEEAH
What is the function of this protein?
Iron-sulfur (Fe-S) cluster binding motor protein that has a role in chromosome segregation during mitosis (PubMed:29848660).  Translocates PRC1 to the plus ends of interdigitating spindle microtubules during the metaphase to anaphase transition, an essential step for the formation of an organized central spindle midzone and midbody and for successful cytokinesis (PubMed:15297875, PubMed:15625105).  May play a role in mitotic chromosomal positioning and bipolar spindle stabilization (By similarity).
What are the official names of this protein?
Chromosome-associated kinesin KIF4A, Chromokinesin-A.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Chromokinesin subfamily.
What are the subcellular locations of this protein?
Nucleus matrix. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Midbody. Chromosome. Note=Associates with chromosomes at all stage of mitosis (PubMed:11736643, PubMed:15297875, PubMed:15625105). Chromatin localization is dependent on iron-sulfur cluster binding (PubMed:29848660). In anaphase, associates with the mitotic spindle midzone (PubMed:15297875). In telophase and cytokinesis, co-localizes with CIAO2B at the spindle midzone and midbody (PubMed:29848660, PubMed:15297875). Co-localizes with PRC1 in early mitosis and at the spindle midzone from anaphase B to telophase (PubMed:15297875, PubMed:15625105). Does not localize to the nucleolus (PubMed:11736643).
Protein: MURC_RHILO
Sequence: MKMPQTIGLVHFIGIGGIGMSGIAEVLHNLGYKVQGSDQADSANVQRLRDKGIECFVGHKAENLGDAEVVVVSTAIKKTNPELKAAREKLLPIVRRAEMLAELMRFRQAVAIGGTHGKTTTTSMVATLLEAGGLDPTVINGGIINAYGTNARMGDGEWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGSFDKVREAFRQFVENVPFYGFGVMCTDHPEVQALVGRIEDRRVITYGENAQADVRFTNHRMAGATSEFDVVIRDRKTGSQSTISGLRLPMPGRHNVSNATAAIAVAHELGLSGEAIKKGLSSFAGVKRRFTHTGSWNGVDVFDDYGHHPVEISAVLKAARSATKGRVIAIAQPHRFTRLHDLFNEFSACFNDADTVIVAPVYAAGEDPIDGVSSDELVSRIRAGGHRDARYIEGPTAIAPIIRGLAKPGDFVVFLGAGNITQWAYALPKELAAS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COAD_RUBXD
Sequence: MNIAICPGSFDPITTGHLDIIRRASKLFDHVVVAVGSNLRKQPRLSAAERARLIEKVTADLENVSVEVMEGLLVDFAREQGARVVVKGLRAVSDFESEFEQAQLNRTLYPELETVFIMSASQHSFLSSSAVREIAALGGDVRGLVPDGILETVRQIYSRSDGKI
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ER6L2_HUMAN
Sequence: MQPGSAPPPGRMDPSAPQPRAETSGKDIWHPGERCLAPSPDNGKLCEASIKSITVDENGKSFAVVLYADFQERKIPLKQLQEVKFVKDCPRNLIFDDEDLEKPYFPNRKFPSSSVAFKLSDNGDSIPYTINRYLRDYQREGTRFLYGHYIHGGGCILGDDMGLGKTVQVISFLAAVLHKKGTREDIENNMPEFLLRSMKKEPLSSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTVLHGNRKDNELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEVMKALKCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSGTYFKKQFSDPVEHGQRHTATKRELATGRKAMQRLAKKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVTLILQSSEPCTCRSGQKRRNCCYKTNSHGETVKTLYLSYLTVLQKVANHVALLQAASTSKQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNRDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERLKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQIYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGIHNLFKFRSQGSCLTKDILEREGQVEAGIMTATTWLKEGPPAHKLEMPRQPDCQECRGTEQAAEPLAKEACDLCSDFSDEEPVGATGIKTAKNKAPDSSKASSSPGQLTLLQCGFSKLLETKCKAVEDSDGNTASDDESSDEQPTCLSTEAKDAGCEKNQDSLGTSKHQKLDNILNPKEKHIFYKSEKILEQNISSKSDEKKIKNTDKHCILQNVTESEDSDVICPTQYTTERFPDNSIRFKPPLEGSEDSETEHTVKTRNNDNSRNTDDKRNGIISKKLSPENTTLKSILKRKGTSDISDESDDIEISSKSRVRKRASSLRFKRIKETKKELHNSPKTMNKTNQVYAANEDHNSQFIDDYSSSDESLSVSHFSFSKQSHRPRTIRDRTSFSSKLPSHNKKNSTFIPRKPMKCSNEKVVNQEQSYESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAAHDVFELKQFSQLPANIAVCSSKTYKEKVDADTLPHTKKGQQPSEGSISLPLYISNPVNQKKKKVYHTNQTTFIIGETPKGIRRKQFEEMASYFNSSSVNEFAKHITNATSEERQKMLRDFYASQYPEVKEFFVDSVSQFNNSSFEKGEQRTRKKSDKRESLIKPRLSDSETLSFKDSTNKISQVCSLKTYKRKSVKFQNHISYREEVFFNDAETKKSPVSSTQEIDSGKNSQASEDTVTSRSLNSESETRERRLENTMKDQQDLTRTGISRKEPLLKLENKKIENPVLENTSVISLLGDTSILDDLFKSHGNSPTQLPKKVLSGPMEKAKQRPKDFWDILNEQNDESLSKLTDLAVIETLCEKAPLAAPFKRREEPATSLWKSNEKFLWKKFSPSDTDENATNTQSTT
What is the function of this protein?
May be involved in early DNA damage response.
What are the official names of this protein?
DNA excision repair protein ERCC-6-like 2, DNA repair and recombination protein RAD26-like.
What is the protein family that this protein belongs to?
Belongs to the SNF2/RAD54 helicase family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mitochondrion. Note=Colocalizes with NEK6 in the centrosome. In response to DNA damage, translocates from the cytosol to mitochondria and nucleus in a reactive oxygen species (ROS)-dependent manner.
Protein: IMP4_SCHPO
Sequence: MLRRAVRERRQFIYKRNQELQEAKLNEKRRALRKALEGNKELNKDLQEDSQLQKDYKYDESRATQEETETNLDDEYHRLGEREPKVLVTTSREPSSRLAQFAKEVRLLIPNSYRLNRGNIVVGSLVEAARANDITDIVILHEHRGIPDGLVISHLPYGPTLSFSLHNVVLRHDIPNTGTMSEAYPHLIFENLTSKLGKRVKTALSALFPPDPKDTTPRVVTFANTDDYISFRHHIYAKTGPKQIILSEAGPRFEMKLFEITLGTVDMVDADVEWKLKPYQRHKRDVLAE
What is the function of this protein?
Component of the U3 small nucleolar ribonucleoprotein.  Required for the early cleavages at sites A0, A1 and A2 during 18S ribosomal pre-RNA processing (By similarity).
What are the official names of this protein?
U3 small nucleolar ribonucleoprotein protein imp4, U3 snoRNP protein imp4.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: THIM1_CLOBL
Sequence: MKNKNVIQKMREKIPLIHCITNYVTINDCANILLSFGASPAMCEAYDEVYDFVSISSALYINLGTLTKEQETAAVLASISAKNHNVPVVIDPVGCPAIKRKVEVINRIAEVGRIDIIKGNIGEIKFLAGMDSETRGVDSLDNGENALNACTQLAKKYNCIVAATGQKDFVSDGKRGSVIKNGTEMLTKVTGAGCMLGALCAATCANFEDKLVSTTAAILSMNIAGEKAYEKAQLPGSFRIALIDNIYMISDEEIWERGNVEWK
What is the function of this protein?
Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ).
What are the official names of this protein?
Hydroxyethylthiazole kinase 1, 4-methyl-5-beta-hydroxyethylthiazole kinase 1, TH kinase 1, Thz kinase 1.
What is the protein family that this protein belongs to?
Belongs to the Thz kinase family.
Protein: GLPO_MYCPN
Sequence: METRDVLIVGGGVIGCATAYELSQYKLKVTLVEKHHYLAQETSHANSGVIHTGIDPNPHKLTAKYNILGKKLWLNTYFKRLGFPRQKIRTLIVAFNEMEREQLEVLKQRGIANQINLEDIQMLSKEETLKLEPYVNPEIVAGLKIEGSWAIDPVLASKCLALAAQQNKVQICTNTEVTNISKQVDGTYLVWTNNETTPSFKVKKIIDAAGHYADYLAHLAKADDFEQTTRRGQYVVVTNQGELHLNSMVFMVPTIHGKGVIVSPMLDGNFLVGPTALDGVDKEATRYITKDAPCMLTKIGKHMVPSLNINNALISFAGSRPIDKATNDFIIRVAHNDPDFVILGGMKSPGLTAAPAIVREAVRLLNWKLTKKPNWNGKYNLPWI
What is the function of this protein?
Catalyzes the oxidation of glycerol 3-phosphate to dihydroxyacetone phosphate (DHAP), with a reduction of O2 to H2O2.  The formation of hydrogen peroxide by this enzyme is crucial for cytotoxic effects of M. pneumoniae on host cells.  Is involved in the metabolism of glycerol and is essential for glycerol utilization; glycerol is one of the few carbon sources that can be utilized by M. pneumoniae for growth (PubMed:19028882).  To a lesser extent, is also able to use glyceraldehyde 3-phosphate (GAP), an intermediate in the glycolysis pathway, as a substrate (but the structure of the product has not been elucidated).  Therefore, in the absence of glycerol, GAP may serve as a substrate in the GlpO reaction to supply H2O2 during mycoplasma infection (PubMed:25712468).  Does not show any dehydrogenase activity with NAD(+) (PubMed:19028882).
What are the official names of this protein?
Glycerol 3-phosphate oxidase, GlpO, L-alpha-glycerophosphate oxidase.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Lipid-anchor. Note=Is present predominantly in the cytoplasm, but a few proteins can also be detected at the cell surface.
Protein: CEBPE_RAT
Sequence: MSHGTYYECEPRGGQQPLEFSGGRAGPGELGDMCEHEASIDLSAYIESGEEQLLSDLFAMKPTPEARSLKGPGTPSFPHYLPADPRPFAYPSHTFGPDRKALGPGIYSNPGSYDPRAVAVKEEPRGPEGNRGTGRGSYNPLQYQVAHCGQTAVHLPPTLAAPGQPLRVLKAPVAAAAPPCSPLLKAPSPAGPSHKGKKAVNKDSLEYRLRRERNNIAVRKSRDKAKRRIMETQQKVLEYMAENERLRSRVDQLTQELDTLRNLFRQIPEAASLIKGVGGCS
What is the function of this protein?
Transcriptional activator.  C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers.  Required for the promyelocyte-myelocyte transition in myeloid differentiation.
What are the official names of this protein?
CCAAT/enhancer-binding protein epsilon, C/EBP epsilon, C/EBP-related protein 1.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. C/EBP subfamily.
What are the subcellular locations of this protein?
Nucleus.