PharMolix/UniProtQA huggingface dataset:
Protein: SYT_LACAC
Sequence: MSFSVTLPDGSKKEFDKAVSVKEVASSIATSLGKAAVGAKVNGQVKPLDYEIDSDVEIAIITDKDEEGLDILRATAAFAFEAVAKKKYPELRLGQHVADEGGFYVDTDKKDQIKVTELPELEKAMEKLIKSGQPIEHVVMDKSELEEMFKDDPFKSDLLKKIDSDKVDAYKLGDFVDFGFDALLPNTGKIKHFKLLSVAGAYWLGKSSNPMLQRIFGTAFFKEAALKEDLKRRAEIKERDHRTIGRDLDLFFVDPKVGAGLPYWMPKGATIRRVVERYIIDREVADGYKHVYTPVLMNLDAYKTSGHWAHYRDDMFPPMDMGDGEMLELRPMNCPSHIQIYKHHIRSYRDLPLRVAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVELDQVQSEFAKILKLIMDVYRDFDITDYYFRLSYRDPKNTDKYFANDEMWERSQKMLKGAMDDLGLDYVEAEGEAAFYGPKLDIQTKTALGNDETMSTIQLDFMLPERFGLTYVGKDGEEHRPVMVHRGIVGTMERFIAYLTEIYKGAFPTWLAPVQAEIIPVNNEAHGEYAEKVRQELAKRGFRVEVDDRNEKMGYKIRESQTQKVPYTLVLGDEEMKNGSVNVRRYGTDEEISKSLDDFINEIDADVKSYSREN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN367_DANRE
Sequence: MADSKHQVIFCNDSPKRVLVSVIKTTPIKPRTTADSLMPTSPGFSDFMVYPWRWGENAHNVTLGPGSGSGAASPTRTSSSPAEADPLSCPEHLKDGIRRGRPRADTVRELINEGENSTSRIRCNICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPFVCSEKACGSRFTHANRHCAKHPYARLKREEPTGGPGKSQGADNKAVAEWLTKYWQTREQRSPVPGKAKPQNKSPLEDQEQQDPLDFLPSDEGEEEEQEEEKNAPSGGVVTARRRLQEQRERLHGALALIELANNLSA
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Zinc finger protein 367.
What is the protein family that this protein belongs to?
Belongs to the krueppel C2H2-type zinc-finger protein family.
What are the subcellular locations of this protein?
Nucleus.
Protein: EFMT3_MOUSE
Sequence: MASSRTDPETEPESVFPREIRLFTDSYSESSRFCFCGHELSITQNFGSRLGVAARVWDAALSLCDYFESQNVDFRGKKVIELGAGTGIVGILAALQGGDVTITDLPVALEQIQDNVHANVPPGGRARVCALSWGIDQHVFPGNYDLVLGADIVYLEPTFPLLLGTLRHLCGPHGTIYLASKMRAEHGAETFFRRLLPQHFHLELAQRDEDVNVNIYRARHREVAPAGQHPFC
What is the function of this protein?
Protein-lysine methyltransferase that selectively mono-, di- and trimethylates 'Lys-165' of the translation elongation factors EEF1A1 and EEF1A2 in an aminoacyl-tRNA and GTP-dependent manner (By similarity).  EEF1A1 methylation by EEF1AKMT3 is dynamic as well as inducible by stress conditions, such as ER-stress, and plays a regulatory role on mRNA translation (PubMed:28108655).
What are the official names of this protein?
EEF1A lysine methyltransferase 3, Methyltransferase-like protein 21B, Protein-lysine methyltransferase METTL21B.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. METTL21 family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Protein: RACB_DICDI
Sequence: MQSIKLVVVGDGAVGKTCLLISYTSNSFPTEYVPTVFDNYSANVMVDNKTVSLGLWDTAGQEDYDRLRPLSYPQTDVFLICFAIISQTSYTNVKSKWWPEVTHHCPNCTIILVGTKCDLREDKESLEKLREKHQQPLTFQQGEQMAKEIKAFCYMECSALTQKGLKQVFDEAIKAVIFPDRDKATNKKNSKCSIL
What are the official names of this protein?
Rho-related protein racB.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rho family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: ADRO_YEAST
Sequence: MSFVQIRHISSQINRKTVSIVGSGPSGFYTAYHLLKKSPIPLNVTIWEKLPVPFGLSRYGVAPDHPEVKNCEETFTTCAEEFSSPTNQKHKFSFVGGITIGKEILLKELLDNQDAVILSYGCTGDRKLNIPGELGTKGVFSSREFVNWYNGHPDFAKDKRFTDFDWSKVSKVGIIGNGNVALDITRVLISNQIDEIWENTDISSLALNLLRRAPVKDVKLIARRDFVHSKFTNKELRELWELEKYGIRGRIDPKFFQKEMFDPSKYDRAFNRRVEMCSEYLKPFNERSKKNYKKAPPPSSGYDKFWELDYLKTPLKINRDDFGAINSLSLCNNRLNEDNSLQPLKDVNNIMTYKVDLLITSLGYAGVPMPEFSKLSIGFDKDHIANKQGRVLTSSGEIFPHLYASGWIRKGSQGVIASTMQDAFEVGDRVIQDLVVSGALSLENSIDLSNIKHTTWKDWERINKKELLRGKKEHKTRSKFLTFEELWNGVEGI
What is the function of this protein?
Adrenodoxin reductase transfers electrons from NADPH to adrenodoxin, which subsequently donates them to the cytochrome P450 forms.
What are the official names of this protein?
Probable NADPH:adrenodoxin oxidoreductase, mitochondrial, AR, Adrenodoxin reductase, Ferredoxin--NADP(+) reductase, Ferredoxin reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 1 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein.
Protein: PFD4_CAEBR
Sequence: MATQAKVSAEDQALLNKFARSYQLQTQLKAECKEMKTLVENINEATDEVLLLDDEDSASIPCRIGSCFVHFNSDSLNEHLEAKKASTETVLAEKTNELETITAEMERIKKVLYGKFGDQINLDAEE
What is the function of this protein?
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it.  Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.  Appears to play a non-essential role (By similarity).
What are the official names of this protein?
Probable prefoldin subunit 4.
What is the protein family that this protein belongs to?
Belongs to the prefoldin subunit beta family.
Protein: KDSA_ALIF1
Sequence: MQNQKTVKIGNIDVANDKPFTLFAGMNVLESRDLAMQICEKYVEVTDRLGIPYVFKASFDKANRSSVHSYRGPGMEEGLKIFQELKDTFGVKIITDIHTEAQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFMSPDQVGNIIDKFSECGNENIILCERGSCMGYDNLVVDMLGFGVMKKASNGSPIIFDVTHSLQNRDPSGKASGGRRSQTVELAKAGLATGIAGLFIEAHPNPDKALCDGPSALPLDQLEPFLKQMKSLDDLIKGFEHIDIK
What are the official names of this protein?
2-dehydro-3-deoxyphosphooctonate aldolase, 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase.
What is the protein family that this protein belongs to?
Belongs to the KdsA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: INSB8_ECOLI
Sequence: MPGNSPHYGRWPQHDFTSLKKLRPQSVTSRIQPGSDVIVCAEMDEQWGYVGAKSRQRWLFYAYDSLRKTVVAHVFGERTMATLGRLMSLLSPFDVVIWMTDGWPLYESRLKGKLHVISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ
What is the function of this protein?
Absolutely required for transposition of IS1.
What are the official names of this protein?
Insertion element IS1 8 protein InsB.
What is the protein family that this protein belongs to?
Belongs to the transposase 27 family.
Protein: FADA_AERS4
Sequence: MKDVVIVDCIRTPMGRSKGGAFRNVRAEDLSAHLMSSILLRNPNLDPNEIEDIYWGCVQQTLEQGFNIARNAALLAGIPKQVGAVTVNRLCGSSMQALHDASRAIQVGDGDIFIIGGVEHMGHVPMSHGVDFHPGMAKSVAKASGMMGLTAEMLGKLHGISRQQQDEFAARSHRRAYAATVEGRFAREIVGLEGHDASGARFFYDYDEVIRPETTVETLSQLRPVFDPVNGTVTAGTSSALSDGASAMLVMSADRAKALGLTPRVRVRSMAVAGCDAAIMGYGPVPATQKALKRAGLTIGDIDLVELNEAFAAQSLPCVKDLGLLDVAEEKVNLNGGAIALGHPLGCSGSRISTTLIHLMEEKDANLGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_BACAC
Sequence: MAITAQMVKELREKTGAGMMDCKKALTETNGDMEKAIDFLREKGIAKAAKKADRIAAEGLTFIETNGNDGLILELNSETDFVAKNEGFQTLIKELAAHLLANKPANVEEAMAQTMENGKKVEEHINEAIAKIGEKLTLRRFEIVSKTDADAFGAYLHMGGRIGVLTVLEGSTDEAAAKDVAMHIAAVNPKYIDRDAVTAEEVEHERQVLTQQALNEGKPEKIVAKMVEGRLGKFFEEICLLDQAFVKNPDMKVRQFVESKGGTLKGFVRYAVGEGIEKREDNFAEEVMNQVKGSN
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CDD_MYCPN
Sequence: MKVDLDWVHHKLQEVVNHAYTPFSKFKVACMLVANNQAFYGVNIENASYPVTLCAERSAIANMVTSIGKATIDYVFVYFDTKTPTNSPCGMCRQNIFEFATDKTQLFCIEKDKSFKQFTIPEILKGGFRSYEQ
What is the function of this protein?
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
What are the official names of this protein?
Cytidine deaminase, CDA, Cytidine aminohydrolase.
What is the protein family that this protein belongs to?
Belongs to the cytidine and deoxycytidylate deaminase family.
Protein: AROE_PELUB
Sequence: MKKTFLVIGNPIKHSLSPKLHNYWIKKYKINATYEKNLLDHSEIEDLIFNIRKEKIHGLNITVPFKKMIIPFLDELSEEAEISQSVNTIYKRDNKIIGDNTDIEGFKLSLEKTEQNVKNKKALILGAGGVVSSIIIALKKIQIEKIYLSNRTELKAIELKKHFPEIEIIKWGETIDFDMIINATSIGLKEEDEININYQKISKDKFFYDVIYNPPETNFLKNAKKYGGITKNGKMMFIYQAQKAFFIWHKIVPEVDSETINLLDV
What is the function of this protein?
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids.  Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
What are the official names of this protein?
Shikimate dehydrogenase (NADP(+)), SDH.
What is the protein family that this protein belongs to?
Belongs to the shikimate dehydrogenase family.
Protein: MRAZ_BORPA
Sequence: MFQGSSALTLDAKGRISIPTRHRDALMDRAEGRLTLTRHPDGCLLVYPRPEWEEKRAQIAAFPMSARALQRLLLGNAQDVDIDGSGRVLIAPELRNASGMTRDVMLLGMGAHFELWDAASLARREAEDLAQGMPDVLNQFSF
What are the official names of this protein?
Transcriptional regulator MraZ.
What is the protein family that this protein belongs to?
Belongs to the MraZ family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: K1A_HETHE
Sequence: MKFQMIAAVLLIAFCLSVVVTARMELQDDEDMKNGSFQKRRTCIDTIPKSRCTAFQCKHSMKYRLSFCRKTCGTC
What is the function of this protein?
Inhibits voltage-gated potassium channels (Kv) with higher potency for Kv1. 1/KCNA1 and Kv1. 3/KCNA3.
What are the official names of this protein?
Kappa-thalatoxin-Hhe2a, Kappa-TATX-Hhe2a, Kappa1.3-thalatoxin-Hh1a, Kappa1.3-TATX-Hh1a, Kappa1.3-TLTX-Hh1a, Potassium channel peptide toxin hh-k, HhK.
What is the protein family that this protein belongs to?
Belongs to the sea anemone type 1 potassium channel toxin family. Type 1a subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst.
Protein: ELN_BOVIN
Sequence: MRSLTAAARRPEVLLLLLCILQPSQPGGVPGAVPGGVPGGVFFPGAGLGGLGVGGLGPGVKPAKPGVGGLVGPGLGAEGSALPGAFPGGFFGAGGGAAGAAAAYKAAAKAGAAGLGVGGIGGVGGLGVSTGAVVPQLGAGVGAGVKPGKVPGVGLPGVYPGGVLPGAGARFPGIGVLPGVPTGAGVKPKAQVGAGAFAGIPGVGPFGGQQPGLPLGYPIKAPKLPAGYGLPYKTGKLPYGFGPGGVAGSAGKAGYPTGTGVGPQAAAAAAKAAAKLGAGGAGVLPGVGVGGPGIPGAPGAIPGIGGIAGVGAPDAAAAAAAAAKAAKFGAAGGLPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGVGVPGALSPAATAKAAAKAAKFGARGAVGIGGIPTFGLGPGGFPGIGDAAAAPAAAAAKAAKIGAGGVGALGGVVPGAPGAIPGLPGVGGVPGVGIPAAAAAKAAAKAAQFGLGPGVGVAPGVGVVPGVGVVPGVGVAPGIGLGPGGVIGAGVPAAAKSAAKAAAKAQFRAAAGLPAGVPGLGVGAGVPGLGVGAGVPGLGVGAGVPGPGAVPGTLAAAKAAKFGPGGVGALGGVGDLGGAGIPGGVAGVVPAAAAAAKAAAKAAQFGLGGVGGLGVGGLGAVPGAVGLGGVSPAAAAKAAKFGAAGLGGVLGAGQPFPIGGGAGGLGVGGKPPKPFGGALGALGFPGGACLGKSCGRKRK
What is the function of this protein?
Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely.  Molecular determinant of the late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).
What are the official names of this protein?
Elastin, Tropoelastin.
What is the protein family that this protein belongs to?
Belongs to the elastin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, extracellular matrix. Note=Extracellular matrix of elastic fibers.
Protein: RS9_METCA
Sequence: MAQTQYYGTGRRKSAIARVYTRTGTGQIRINDKSLEEYFGRKTDRMIVMQALEAVEMTDKLDVNVKVIGGGPSGQAGAIRHGLARALIELDEAMRPVLRKAGYVTRDAREVERKKVGLHKARRRPQYSKR
What are the official names of this protein?
30S ribosomal protein S9.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS9 family.
Protein: RS7_BUCCC
Sequence: MPRRRIIGQRKILPDPKFSSELLAKFINILMINGKKSIAENIVYSALHQLSIKVKKKELDIFIAALDNVKPVVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIIDAARKRIDRSMSIRLTNELLDALENKGAAVRKREEVHKMADANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: 3SOC7_MICCO
Sequence: MKTLLLTLVVVTIVCLDFGYTIVCYKRHASDSQTTTCLSGICYKKITRGSSRPEMGCGCPQSSRGVKVDCCMRDKCNG
What are the official names of this protein?
Alpha-neurotoxin homolog 7, NXH7, Alpha-neurotoxin homolog 3, NXH3.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Short-chain subfamily. Orphan group XII sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: US9_SUHVR
Sequence: MPTAAPADMDTFDPSAPVPTSVSNPAADVLLAPKGPRSPLRPQDDSDCYYSESDNETPSEFLRRVGRRQAARRRRRRCLMGVAISAAALVICSLSALIGGIIARHV
What is the function of this protein?
Essential for the anterograde spread of the infection throughout the host nervous system.  Together with the gE/gI heterodimer, US9 is involved in the sorting and transport of viral structural components toward axon tips.
What are the official names of this protein?
Envelope protein US9 homolog, 11 kDa protein.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae envelope protein US9 family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type II membrane protein. Host Golgi apparatus membrane; Single-pass type II membrane protein. Host smooth endoplasmic reticulum membrane; Single-pass type II membrane protein. Host cell membrane; Single-pass type II membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN), maybe through an interaction with PACS-1 sorting protein.
Protein: PURA_SHEFN
Sequence: MGKNVVVLGTQWGDEGKGKIVDLLTEQAKYVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRDNVKCIIGNGVVVAPDALMKEINMLKGRGVPVEERLLISEACPLILPFHCALDIAREKARGNQAIGTTGRGIGPAYEDKVSRRGLRIGDLFNAELFATKLQEVMKYHNFMLTEYYKVEAVDYQQTLDDALAIADYLKSMCTDVSEMLDVARKAGEPILFEGAQGTLLDIDHGTYPFVTSSNTTAGGVATGSGFGPRHLDYVLGIMKAYTTRVGAGPFPTELANEIGDYIGEKGQEFGATTGRKRRPGWLDAVAMRRAVQINSVSGFCLTKLDVLDGLKEVKICVGYQYADGTVSKVTPLAAEGYDLVTPIYETMPGWSETTFGATTIEQLPPAAINYIKRLEELLETPIDIISTGPDRNETMILVNPFK
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP6_PICGU
Sequence: MERCDGVMFAARYDPEDGKRESVSEDTESERESESGSESESESEKETESESEKETESESESETGNTGKTGETRKSIGLESVSDSDSDSGSQSRSDSDVEMKEVDASNSNIVSDSSKHKSVLKKLRTSLSAQKAENSTSNSDSDESSVPTHDLAPLPQPALPRDQRLTATTNHIGNLDWLATPIYASTTETVPFSSFGLSSSMVKNLQSNGFSSAFSVQVSVLKLLLPDMESQAIRPDIGGDLLVNAATGSGKTLGYAIPIIESLRNRIVPRVRAIVLVPTKPLISQVKATFAMLSKNTNLSVVSLRSDISINDEAQRLQVVPDIIVSTPGRLVEHLTNGHINLKSLRYLVIDEADRLLNQSFQNWCETLMSRIDSNPISELDQTWRPSVQKLVFSATLTTDAGRLSMLKLQRPRLIIVNDRHELVNELFTVPATLQEYKLSLGSARSSAKPLVLAKFLMSEQKLVNTLVFAKSNEASLRLCRLLQLLFRVFGLDVTVSYLNSTNNAASTRAKILKDFANQTVHILVVTDLIARGIDIATITNVINYDLPNSSRDYVHRVGRTARANQDGEAYTMCFGKGETKWFTQLVREVSRQTEVKDVEKGFRDLVSREDEAKYDTCLEELQRQVFEGV
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase DBP6.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX51/DBP6 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AUTS2_HUMAN
Sequence: MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDGFAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSESASGESKGFHRSSSRERLSDSSAPSSLGTGYFCDSDSDQEEKASDASSEKLFNTVIVNKDPELGVGTLPEHDSQDAGPIVPKISGLERSQEKSQDCCKEPIFEPVVLKDPCPQVAQPIPQPQTEPQLRAPSPDPDLVQRTEAPPQPPPLSTQPPQGPPEAQLQPAPQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLSAYNSSSLSLNSLSSSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTPTLQPPAHSHHPNMFAPPTALPPPPPLTSGSLQVAGHPAGSTYSEQDILRQELNTRFLASQSADRGASLGPPPYLRTEFHQHQHQHQHTHQHTHQHTFTPFPHAIPPTAIMPTPAPPMFDKYPTKVDPFYRHSLFHSYPPAVSGIPPMIPPTGPFGSLQGAFQPKTSNPIDVAARPGTVPHTLLQKDPRLTDPFRPMLRKPGKWCAMHVHIAWQIYHHQQKVKKQMQSDPHKLDFGLKPEFLSRPPGPSLFGAIHHPHDLARPSTLFSAAGAAHPTGTPFGPPPHHSNFLNPAAHLEPFNRPSTFTGLAAVGGNAFGGLGNPSVTPNSMFGHKDGPSVQNFSNPHEPWNRLHRTPPSFPTPPPWLKPGELERSASAAAHDRDRDVDKRDSSVSKDDKERESVEKRHSSHPSPAPVLPVNALGHTRSSTEQIRAHLNTEAREKDKPKERERDHSESRKDLAADEHKAKEGHLPEKDGHGHEGRAAGEEAKQLARVPSPYVRTPVVESARPNSTSSREAEPRKGEPAYENPKKSSEVKVKEERKEDHDLPPEAPQTHRASEPPPPNSSSSVHPGPLASMPMTVGVTGIHPMNSISSLDRTRMMTPFMGISPLPGGERFPYPSFHWDPIRDPLRDPYRELDIHRRDPLGRDFLLRNDPLHRLSTPRLYEADRSFRDREPHDYSHHHHHHHHPLSVDPRREHERGGHLDERERLHMLREDYEHTRLHSVHPASLDGHLPHPSLITPGLPSMHYPRISPTAGNQNGLLNKTPPTAALSAPPPLISTLGGRPVSPRRTTPLSAEIRERPPSHTLKDIEAR
What is the function of this protein?
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.  PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:25519132).  The PRC1-like complex that contains PCGF5, RNF2, CSNK2B, RYBP and AUTS2 has decreased histone H2A ubiquitination activity, due to the phosphorylation of RNF2 by CSNK2B (PubMed:25519132).  As a consequence, the complex mediates transcriptional activation (PubMed:25519132).  In the cytoplasm, plays a role in axon and dendrite elongation and in neuronal migration during embryonic brain development.  Promotes reorganization of the actin cytoskeleton, lamellipodia formation and neurite elongation via its interaction with RAC guanine nucleotide exchange factors, which then leads to the activation of RAC1 (By similarity).
What are the official names of this protein?
Autism susceptibility gene 2 protein.
What is the protein family that this protein belongs to?
Belongs to the AUTS2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytoskeleton. Cell projection, growth cone. Note=Detected both in cytoplasm and nucleus. Colocalizes with RAC1 at actin-rich growth cones. Detected on the promoter region of actively transcribed genes.
Protein: RNY_CAMC5
Sequence: MIEVLIGLGAGVAGVGAGYLYAKKINDANYNIFLEQAKAKAKAIEYEAELTLKNSKISVQEAEFEAKKRYDDKTTKLQKEYSQKFDELNKKEQILLNEQELLNENKELFEKDRNEAKLTYEEGLNLKATYQSKVQEALKVLEHAAGLTEDEAREVVLKKVEEKSRADIAHIVRKHEEEAKREAKKRVNYILAQATSRFAGEFAAERLINVVNIKNDELKGRIIGKEGRNIKTLEMVLGVDIIIDDTPHAIILSSFNLYRRAIATRVIELLVEDGRIQPARIEDLHKKVTEEFEQSIQEEGENIVIDLGLSKIHPEITKLIGKLKFRASYGQNALAHSLEVAHLAGIIAAETGGDEKLAKRAGLLHDIGKALTHEFEGSHVDLGAEICKRYKEHPVVINAIYAHHGHEEATSIESAAVCAADCLSAARPGARREVLESFLKRVEEVENIAKSKDGIKQAYAINAGREIRVIANAKLINDDEAVLVAKEIAKEIEEKVQYPGEIKVSVIRETRAVDYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: CRTDH_NONDD
Sequence: MKNAIVIGAGIGGLAAALRLRHQGYSVTIFEKNDYAGGKLHAIEKDGYRFDLGPSLFTLPHLVENLFALFPEEIIDFGYKSKAISFHYFWDDGTLFKASTDSSQFIEDASKVFKEEKSTIKKYLAKSKSKYELTKSLFLEKSLHKATTYFSLDTVKAIVHAPFLGLNNTLNDENSKFKNPKLTQLFNRYATYNGSSPYQTPGIMTMIPHLELGLGTYYPDGGMHRISQSLFELAQKVGVKFRFRESVTNITTSKNKVTGVETKNGSYLSDLVVSNMDIVPTYRNLMKDVPAPEKTLSQERSSSALIFYWGIDREFPELDLHNILFSEDYKTEFEHIFEHKTLAQDPTVYINITSKESSNDAPAGHENWFVMINAPGDYGQDWEQLVEESKKQIIAKIKKCLHVDISKHITTEYILTPQGIEKNTSSYRGALYGAASNNKFAAFLRHPNFNGKIKNLYHVGGSVHPGGGIPLCLLSAQITADLIQKEQ
What is the function of this protein?
Catalyzes the introduction of a C-3,4 double bond into 1'-hydroxy-gamma-carotene and rhodopin (1-hydroxylycopene) to yield 1'-hydroxytorulene and (3E)-3,4-didehydrorhodopin, respectively (By similarity).  Can also use 1-hydroxy-all-trans-1,2-dihydro-neurosporene, 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene and 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene (By similarity).  Probably involved in the synthesis of myxol, a gamma-carotene derivative (Probable).  May use FAD as a proton acceptor (Probable).
What are the official names of this protein?
1-hydroxycarotenoid 3,4-desaturase, 1'-hydroxy-gamma-carotene 3,4-desaturase, 1-hydroxycarotenoid 3,4-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the carotenoid/retinoid oxidoreductase family.
Protein: RL13_CLOK1
Sequence: MKSYIAKAEQIERKWYVVDAAGKPLGRVASQVASVLRGKHKPIFTPHVDTGDFVIVINSEKVLLTGKKLDQKMLRHHSLYPGGLKETPYREALNKKPEFVFQEAVRRMLPKGVLGRKMLKKLKVYRGTEHNNEAQKPEVLELKY
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: CCM1_LACTC
Sequence: MLGRRLAGAKPQSGALFKRFVVIPASSKARRRRRDVGGIRKNVSVEELELDKALDLRDPKELEFKLRQLREFTKNLATQIRVADDLVKKEAAQKELGNKSKEEDTADAASVILGTHNHHDRYQRRSLLQGEDLSSIILSVSHQVKKLLPEAILKRINDDELVLRSLINHRNSDWNAIISKLDQSPEKLDGVSQRALKNYILSKAKNLSLGSIRKADAMLLSNINHDLTKFNTSMYEFLFYNLSNLKPSQDPSSKYNNEVYTVMESLLDRYDEAQKVIAGKNVAIEAQEGIMPKVEMNQFILNCCIKFASKLLDVSKMNRFLTKFNRDYHILPNKENYTVIAQFYTKLGLHDKAWDIFATMKFLSADHKPDAKTYTCMLSLCNKEKNYAKAIDLFNEMIDLKVDPTPETLNALVKTLATVSGDPVASEGKAESLRLLAWKYLHQNEDLVNLRSGNFEDTILAMMSLCAYDGDAGLARALYFKYITTRFKSNFESWRMRQGDHSSVDYKKVWASTLNPFLFNYLMLAYANYSPGKLPLLLGFEQGAVTRRNLINNVDYLYKFQNDEAGPRAKLPMLPLADISEPSQILLESRAVWQFNLEFGGLCDLRISPLGSSKVLKDLAASAESIEDFSFQVLHQIALWKTQIVNHNALNPKSIMTYLTIPLKLGEKKEFLLRMSEFSYEQQTFEQHISSLYMNTKQQLLTARPGSSTHLTHSEIKKQPSSQTSFNEESSLAFLSSMKHKIIRNSSIYELTMKAAIRFQDQALATKAWESRGSYRKTLAFQNLPVAERTKKDAAFASLMVDFFTQQQMYTDAMGIIMASQRHISWRYPMVKRLHRKLVELEDTRSIKILMEIVNKRSKSDSSAEAVTSLG
What is the function of this protein?
RNA-binding protein involved in the specific removal of group I introns in mitochondrial encoded transcripts.  Maintains the stability of the small subunit mitochondrial 15S rRNA and thus the expression of the mitochondrial genome (By similarity).
What are the official names of this protein?
Mitochondrial group I intron splicing factor CCM1.
What is the protein family that this protein belongs to?
Belongs to the CCM1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: RS3_CHRVO
Sequence: MGQKIHPTGFRLAVNKNWSSKWFASSQNFPEMLKQDIEVREFLKKRLGHASVGRVTIERPAKSARITIHSARPGVVIGKKGEDIEVLKQELQKRLGVPVHVNIEEVRKPELDAQIIADGIASQLEKRVMFRRAMKRAMQNAMRLGAEGIKIMSSGRLNGIDIARSEWYREGRVPLHTLRADVDYATSEAKTTYGIIGIKVWVYKGELKPGQVQATPAAPEKKMRKGARNAAAN
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.