PharMolix/UniProtQA huggingface dataset:
Protein: NRAM_I72A8
Sequence: MNPNQKIITIGSVSLTIATICFLMQIAIQVTTVTLHFKQYECDSPANNQVMPCEPIIIERNITEIVYLTNTTIEKEICPKLVEYRNWSKPQCKITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPGKCYQFALGQGTTLDNKHSNDTIHDRTPHRTLLMNELGVPFHLGTRQVCIGWSSSSCHDGKAWLHVCVTGYDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTKILFIEEGKIVHISPLSGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINVKDYSIDSSYVCSGLVGDTPRNNDRSSNSYCRNPNNEKGNHGVKGWAFDDGNDVWMGRTISEDSRSGYETFKVIGGWSTPNSKLQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGREQETRVWWTSNSIVVFCGTSGTYGTGSWPDGADINLMPI
What is the function of this protein?
Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates.  Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release.  Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface.  These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell.  Otherwise, infection would be limited to one round of replication.  Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors.  May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells.  Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport.  May additionally display a raft-association independent effect on budding.  Plays a role in the determination of host range restriction on replication and virulence.  Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication.
What are the official names of this protein?
Neuraminidase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 34 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type II membrane protein. Note=Preferentially accumulates at the apical plasma membrane in infected polarized epithelial cells, which is the virus assembly site. Uses lipid rafts for cell surface transport and apical sorting. In the virion, forms a mushroom-shaped spike on the surface of the membrane.
Protein: RS27_CANAL
Sequence: MVLVQDLLHPSPATEAKQHKLKTLVQQPRSFFMDVKCQGCLNITTVFSHAQTAVTCDSCSTVLCTPTGGKAKLTEGCSFRRK
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
40S ribosomal protein S27.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS27 family.
Protein: MUTL_PSEA8
Sequence: MSEAPRIQLLSPRLANQIAAGEVVERPASVAKELLENSLDAGSRRIDVEVEQGGIKLLRVRDDGRGIPADDLPLALARHATSKIRELEDLERVMSLGFRGEALASISSVARLTMTSRTADAGEAWQVETEGRDMQPRVQPAAHPVGTSVEVRDLFFNTPARRKFLRAEKTEFDHLQEVIKRLALARFDVAFHLRHNGKTIFALHEARDELARARRVGAVCGQAFLEQALPIEVERNGLHLWGWVGLPTFSRSQPDLQYFYVNGRMVRDKLVAHAVRQAYRDVLYNGRHPTFVLFFEVDPAVVDVNVHPTKHEVRFRDSRMVHDFLYGTLHRALGEVRPDDQLAPPGATSLTEPRPTGAAAGEFGPQGEMRLAESVLESPAARVGWSGGSSASGGSSGYSAYTRPEAPPSLAEAGGAYKAYFAPLPAGEAPAALPESAQDIPPLGYALAQLKGIYILAENAHGLVLVDMHAAHERITYERLKVAMASEGLRGQPLLVPESIAVSEREADCAEEHSSWFQRLGFELQRLGPESLAIRQIPALLKQAEATQLVRDVIADLLEYGTSDRIQAHLNELLGTMACHGAVRANRRLTLPEMNALLRDMEITERSGQCNHGRPTWTQLGLDELDKLFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: PSAC_SACOF
Sequence: MSHSVKIYDTCIGCTQCVRACPTDVLEMIPWDGCKAKQIASAPRTEDCVGCKRCESACPTDFLSVRVYLGPETTRSMALSY
What is the function of this protein?
Apoprotein for the two 4Fe-4S centers FA and FB of photosystem I (PSI); essential for photochemical activity.  FB is the terminal electron acceptor of PSI, donating electrons to ferredoxin.  The C-terminus interacts with PsaA/B/D and helps assemble the protein into the PSI complex.  Required for binding of PsaD and PsaE to PSI.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.
What are the official names of this protein?
Photosystem I iron-sulfur center, 9 kDa polypeptide, PSI-C, Photosystem I subunit VII, PsaC.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: MURA_YERE8
Sequence: MDKFRVQGRTRLSGEVTISGAKNAALPILFAALLAEDPVELQNVPKLKDIDTTIKLLSQLGVKIERDAASGSVFVDASGVDEFCAPYDLVKTMRASIWALGPLVARFGKGQVSLPGGCAIGARPVDLHITGLEQLSAEIKLEEGYVKASVNGRLKAAHIVMDKVSVGATVTIMSAATLAEGTTVIENAAREPEIVDTANFLNTLGAKITGAGTDRITIEGVARLGGGVYRVLPDRIETGTFLVAAAISGGKVVCRQTRPDTLDAVLAKLREAGADIEVGDDWISLDMHGKRPKAVTLRTAPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAHAEIESNTVICYGVEQLSGAQVMATDLRASASLVLAGCIADGVTIVDRIYHIDRGYEGIEDKLRALGAKIERVKGE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: 14331_MAIZE
Sequence: MASAELSREENVYMAKLAEQAERYEEMVEFMEKVAKTVDSEELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEEGRGNEDRVTLIKDYRGKIETELTKICDGILKLLETHLVPSSTAPESKVFYLKMKGDYYRYLAEFKTGAERKDAAENTMVAYKAAQDIALAELAPTHPIRLGLALNFSVFYYEILNSPDRACSLAKQAFDEAISELDTLSEESYKDSTLIMQLLRDNLTLWTSDISEDPAEEIREAPKRDSSEGQ
What is the function of this protein?
Is associated with a DNA binding complex to bind to the G box, a well-characterized cis-acting DNA regulatory element found in plant genes.
What are the official names of this protein?
14-3-3-like protein GF14-6.
What is the protein family that this protein belongs to?
Belongs to the 14-3-3 family.
Protein: MMPA_CAUVC
Sequence: MIGFLIMLVSLLFVLSVVVTVHELGHYWAARACGVAIERFSIGFGAPLISWRDKRGVEWCVASIPLGGYVRFAGDENAASVPDQNDLDAMRNEIRRREGDDAVNRYFHFKPVWQRAFIAVAGPMANFILAILVFAVILVSFGAQKTSTTVGEVVAGTPAAAAGFKPGDVILKADNRQIRSFQDIQGYVALRANMPIDFAVERDGRTVHLTATPRLVERQNEISGRVKVGELGLRSAPGGRFERSSLLSAIPDATVEVWDMIKTIAFYLGRLLMGQLPADQISGIIGIGHTAGAVTNGVVEQAPNGKALAIGLIYSQFWLIASLSVSIGFMNLLPIPVLDGGHLVMYAYEAVAKRPLRAEFQAAGFRAGLALILGFMLFAAWNDLNRYDVFKFIGGLFT
What is the function of this protein?
Involved in the regulated intramembrane proteolysis (RIP) of the short isoform of PodJ protein (PodJS), during the swarmer-to-stalked transition.  The cleavage occurs near or within the single transmembrane of PodJS thereby releasing the N-terminal segment into the cytoplasm for subsequent degradation.  It contributes to preserve asymmetry in the next cell cycle through sequential degradation.
What are the official names of this protein?
Metalloprotease MmpA, Membrane metalloprotease A.
What is the protein family that this protein belongs to?
Belongs to the peptidase M50B family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RPOB_CLOB1
Sequence: MVHPVQVGKRTRMSFSRLKEVGQMPNLIEVQLDSYDWFLKEGLQEVFDDINPIQDYTGNLNLEFVGYKLDLDSIKYSVEECKERDSTYAAPLKVKVRLLNKETGEIKEQEVFMGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYYDMTVDKTGSKLFSATVIPNRGAWLEYETDSNNIIYVRIDKTRKLPITILARALGYGTDAEIIEFFGEDERLKATIEKDNTKTREEALLEIYKRLRPGEPPTVDSAESLIESLFFDAKRYDLSRVGRYKFNKKLAIHLRITNQIADQDIVNPQTGEILVQKGEKIDKDKAIEIQNCGINEVYIKIDDKSFKVIGNHFVDIHSLVPFDISDLNIKEYVFYPVLKEILDNYADEESIKEEIRKNIYRLIPKHIIREDIYATINYELALSYDIGYKDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVKERMTIQDQEVITPQALINIRPVAASIKEFFGSSQLSQFMDQTNPLSELTHKRRLSALGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLATFAKVNEYGFIETPYRRIDPKNKRATNDIVYMTADEEDLYVIARSDEPIDENGYFIDDKVTVRAKEEVLVVPVSEVEYMDISPRQLVSVATAMIPFLENDDASRALMGSNMQRQAVPLLKPQAPIVGTGIEYKAATDSGVLPKAKNAGTVVYVSADEIRVRRDSDGGIDKYKLLKFKRSNQGTCINQRPIVSKGEVVAKETLLADGPSTDLGEIALGKNILMGFITWEGYNYEDAMLISEQLVKEDVFTSIHIEEYEAEARDTKLGPEEITRDIPNVGEEALKDIDERGIIRIGAEVRSGDILVGKVTPKGETELTAEERLLRAIFGEKAREVRDTSLRVPHGEAGIIVDVKIFTRENGDELPPGVNKLVRCYIAQKRKISVGDKMAGRHGNKGVISRVLPEEDMPFLPDGRPLQICLNPLGVPSRMNIGQVLEVHLGLAASKLGWHIATPVFDGAIESDIVDCLRKAGYSEDGKTVLYDGRTGEPFDNRVTVGYMYILKLAHLVDDKIHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEILTVKSDDVVGRVKTYEAIVKGENIPEPGVPESFKVLIKELQALCLDVKVLNDDNQEIKLKESVDEDADELEVNIEGTENQPEEKEEKEKEDSDEYDDLREEDVEPDLEELSLDDLDLDDFGDEH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: BIP_KLULA
Sequence: MFSARKSSVGWLVSSLAVFYVLLAVIMPIALTGSQSSRVVARAAEDHEDYGTVIGIDLGTTYSCVAVMKNGKTEILANEQGNRITPSYVSFTDDERLIGDAAKNQAASNPKNTIFDIKRLIGLQYNDPTVQRDIKHLPYTVVNKGNKPYVEVTVKGEKKEFTPEEVSGMILGKMKQIAEDYLGKKVTHAVVTVPAYFNDAQRQATKDAGAIAGLNILRIVNEPTAAAIAYGLDKTEDEHQIIVYDLGGGTFDVSLLSIENGVFEVQATAGDTHLGGEDFDYKLVRHFAQLFQKKHDLDVTKNDKAMAKLKREAEKAKRSLSSQTSTRIEIDSFFNGIDFSETLTRAKFEELNLALFKKTLKPVEKVLKDSGLQKEDIDDIVLVGGSTRIPKVQQLLEKFFNGKKASKGINPDEAVAYGAAVQAGVLSGEEGVEDIVLLDVNALTLGIETTGGVMTPLIKRNTAIPTKKSQIFSTAVDNQKAVRIQVYEGERAMVKDNNLLGNFELSDIRAAPRGVPQIEVTFALDANGILTVSATDKDTGKSESITIANDKGRLSQDDIDRMVEEAEKYAAEDAKFKAKSEARNTFENFVHYVKNSVNGELAEIMDEDDKETVLDNVNESLEWLEDNSDVAEAEDFEEKMASFKESVEPILAKASASQGSTSGEGFEDEDDDDYFDDEL
What is the function of this protein?
Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER.  Is required for secretory polypeptide translocation.  May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.
What are the official names of this protein?
Endoplasmic reticulum chaperone BiP, Immunoglobulin heavy chain-binding protein homolog, BiP.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: ABCG8_MOUSE
Sequence: MAEKTKEETQLWNGTVLQDASQGLQDSLFSSESDNSLYFTYSGQSNTLEVRDLTYQVDIASQVPWFEQLAQFKIPWRSHSSQDSCELGIRNLSFKVRSGQMLAIIGSSGCGRASLLDVITGRGHGGKMKSGQIWINGQPSTPQLVRKCVAHVRQHDQLLPNLTVRETLAFIAQMRLPRTFSQAQRDKRVEDVIAELRLRQCANTRVGNTYVRGVSGGERRRVSIGVQLLWNPGILILDEPTSGLDSFTAHNLVTTLSRLAKGNRLVLISLHQPRSDIFRLFDLVLLMTSGTPIYLGAAQQMVQYFTSIGHPCPRYSNPADFYVDLTSIDRRSKEREVATVEKAQSLAALFLEKVQGFDDFLWKAEAKELNTSTHTVSLTLTQDTDCGTAVELPGMIEQFSTLIRRQISNDFRDLPTLLIHGSEACLMSLIIGFLYYGHGAKQLSFMDTAALLFMIGALIPFNVILDVVSKCHSERSMLYYELEDGLYTAGPYFFAKILGELPEHCAYVIIYAMPIYWLTNLRPVPELFLLHFLLVWLVVFCCRTMALAASAMLPTFHMSSFFCNALYNSFYLTAGFMINLDNLWIVPAWISKLSFLRWCFSGLMQIQFNGHLYTTQIGNFTFSILGDTMISAMDLNSHPLYAIYLIVIGISYGFLFLYYLSLKLIKQKSIQDW
What is the function of this protein?
ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane (PubMed:16352607, PubMed:16867993, PubMed:18402465).  Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:12444248, PubMed:14504269, PubMed:14657202, PubMed:25378657).  Plays an important role in preventing the accumulation of dietary plant sterols in the body (PubMed:12444248, PubMed:14657202).  Required for normal sterol homeostasis (PubMed:12444248, PubMed:14657202).  The heterodimer with ABCG5 has ATPase activity (PubMed:16352607, PubMed:16867993).
What are the official names of this protein?
ATP-binding cassette sub-family G member 8, Sterolin-2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Protein: TM129_XENTR
Sequence: MESPEVTFTLAYVVFSVCFVFTPNEFHSAGITVQNLLSGWLGSEDVAFVHYHIRRSTATLLTHSLLPMGYFIGMCFAAPEKELYNVYKAADGWKVFVLITVLLPVTTSILAFYWSQKRWGNHPLAKTLAHHALPQSSWRAVASSINTEFRRIDKFATGAPSARVIVTDTWVMKVTTYRVDVAQQQDIHLTVTDSRQHELSPDSNTPVQFITIRVASVNPRVKPFDIRLNSTEYGELREKLHAPIRNAANVVIHQTLSDMFLETFKSLVEANQVYELSSNQELEPCIGCMQTNANIKLVKYCQEANEGECQQCYCRPMWCLTCMGKWFASRQDQQHPETWLSSHVPCPTCRAKFCIVDVCIVR
What is the function of this protein?
E3 ubiquitin-protein ligase involved in ER-associated protein degradation, preferentially associates with the E2 enzyme UBE2J2.
What are the official names of this protein?
E3 ubiquitin-protein ligase TM129, RING-type E3 ubiquitin transferase TM129.
What is the protein family that this protein belongs to?
Belongs to the TMEM129 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: SSB1_TROWT
Sequence: MDATVTVVGNLTADPELRYTATGAAVVNMTIASTPRMYDRQSGEWKDGEPLFLRGILWREYAINAAASLAKGMRVVAVGKLKQRNYETREGDRRTSVELEIDEIGPTLRYATAKCSRATQAGHGVSPDPWADSQGSQGIDSHTTRSEEITENAKNGEGAGKNELNKKVLVGDNVSYEDFDSDEVPF
What are the official names of this protein?
Single-stranded DNA-binding protein 1, SSB 1.
Protein: HIS8_SYNAS
Sequence: MNAKGESMLSRRLEALTPYVPGEQPRDRKYLKLNTNENPWPPSPRIEALLREYDPDQLRLYPDPWSLSLRQKIARKYSVDVDNIFVGNGSDEILSFVWYAFFDGLYGKLVFPQFTYSFYPVYCDFYEIPYRRIPLRPDFTLDLEAMIENGGEPSCGMAFPNPNAPTGIALTLKQIEDLLNRYPTDRVVVIDEAYIDFGGESAVGLIDRYANLLVARTFSKSFSLAGLRLGYALGSPELIRALFVTKDSFNSYTVGRLTQTIGEIAIEDEAWFAEKIARIIEARDFFSEELKGQGWQVLPSKANFVFVRKPGLTGQTIYETLKERGILVRYFNVEGIRDFVRVTIGKREDMARLLEELKRLF
What are the official names of this protein?
Histidinol-phosphate aminotransferase, Imidazole acetol-phosphate transaminase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
Protein: YR811_MIMIV
Sequence: MDNQAVVDLAIVVDATGSMGTFLSSLSESLQQIVQIIDITNVIQNINIIMYRDYCDSVITASSGWVSKIDDLIPFIRGLRASGGGDTPEAGKTAANNLLDVVKNNTIVIWYADAPPHHKSNARDNFAREINTLIGSDKIFDWIELCDTLAARNIIVYPIINRHHFDTSSFYVAMSTITGGKTLYLESTNEKIITQTTIKLLLSLMGCDNEFKSGVKELVYGSEFNRSSILDENNNAGYLPGTRSSILVNTVDLQVQTHPWLITNLRSLVSLFNADSHYKDKIFAVFKSLMKPTSVLSLTYNTIFATFWRLICRTYDDPRKEVLKEQMSVVLENLKKTNREDHVVVTEWISDSYNQTYEVNDIIKTKAVSKVPALVLDTTRFYLPQEILELSRTCNAKVLSTVVDMLSSIRLIEKEEDLPKTNEQELDSKGRPIPLKYIPLSLPNKYLFSILPHLIAPGSNFSLRPSMILATVAYITNNQILKDRAKNHLEYHKGKWIDQSLPENYTGGFINLMLRVPEFLTDEEISFFKFYQKVFGLLINGSTELDIDMPFTPYKKVCNDFKRECDHCHHIRSFTLLTIDDDGKYKCGLCHSPADDDTDTLNRVYTIISCDTPGETGMTISKDTTLGPSSKEHQDDYHSVYLECKSCLCHYALVNVDKMNVTPKCYGCRFDVYLPNVKCIICTNKYVDPAKIYSDNSETFVCPQCVSDPRSSIDILKVKFKDIYLQNKSTIHSLVGFEMPSDINVFGGHSIFSIKDKINILDHTENPTSLVFNRKFMLNAPIVIIEMLKWINSGSAEKGLCMICFNEFSKSNLRQICGRKVCQSVACYDCMKSWYGENKVGDLIHVNALTCPFCKQCPMFNILAAFNRQVCAMVRTNNSFDIDWWYGWCLKCFQPKKVVEKECSEDAPQLGGKFICEECSNVKPENSKECPNSLCKIPIIKDGGCNHMECTACKKHFCWLCANVSYETSEETYDHLYKIHGGAFEYDQDD
What are the official names of this protein?
Putative ariadne-like RING finger protein R811.
Protein: MUTS_NITMU
Sequence: MSQSSKARLSTDPTVFEAVLNNHTPMMQQYLRIKAQHPDMLMFYRMGDFYELFFDDAEKAAKLLDITLTRRGTSAGEPIKMAGVPYHAAEQYLAKLVKLGESVVICEQVGDPATSKGPVERQVTRIITPGTLTDAALLEDKRDSALLALLVHESTLGLAWLNLAAGQFSVMETSVNNLTAELERLKPAEILLPESLNLAGINDRVIQEKLCVKHLPAWQFDTAAAVRNLSRQFGTHDLSGFGCEDLDVSLGAASALLDYTRLTQGASIGHIKGLRVEREDTYLRMDATTRRNLEISETIRGDAAPTLLSLLDTCSTNMGSRLLCHWLHHPLRDRGLIQNRLNGVSFLMGEAGSGPCLSVRDCLKRVTDIERITARIALKSARPRDLSGLRDSLKRLPAVNNAVAGTATTSSGGSDVSAHVAALIHSMAPDNALVALLEKSLKEEPEVMLRTGGVIADGYDAELDELRAIHNNCDEFLLQLETREKARTGIANLKVEYNRLHGFYIEVTHAHTEKIPDDYRRRQTLKNAERYITPELKAFEEKALSAQSRALEREKLLYGELLDMLSQYIDHLQQVARSVAELDVLATFAERALALDYSLPLFTSDSVIEIQAGRHPVVEKQVDSFIANDVQLGARTGGRRQMLVITGPNMGGKSTYMRQVALIALLAHCGSFVPARSALIGPLDQLFTRIGASDDLAGGRSTFMMEMTEAANILHNATAQSLVLMDEVGRGTSTFDGLALAFAIARYLLEKNRSYTLFATHYFELTRLAEEFAQVANVHLRAVEHKHHIVFLHAVNEGPASQSYGLQVAALAGVPDPVIRTARRYLLKLEQEALSNQPQGDLFSRDDLFWKQDRMPEGSVDKNDSAPEHPVLALLRTIVPDDLSPKQALEQLYGLKKAAEKE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: GSPM_DICCH
Sequence: MNELRRRWQVMSQRERLMALACGGLVVLCLLYYLIWAPWQESVRQWQMTVERERQTVRWMQQQPPRFRRRKVRGGRXPVAISANGIGAQSAVRYGITVLRMQPQESQVSVTLARSDFNNLLHWLAELEQKNGVITQGIDVTAVPNSPGIVEVTRLSLERVL
What is the function of this protein?
Inner membrane component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm.  Plays a role in the complex assembly and recruits OutL resulting in a stable complex in the inner membrane (By similarity).  Provides thus a link between the energy-providing OutE protein in the cytoplasm and the rest of the T2SS machinery (PubMed:11266368).
What are the official names of this protein?
Type II secretion system protein M, T2SS protein M, General secretion pathway protein M, Pectic enzymes secretion protein OutM.
What is the protein family that this protein belongs to?
Belongs to the GSP M family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: PUR2_PYRAB
Sequence: MRVLLVGGGGREHAIGEALARGGAELYVVSKHKNPGLARISRDYGISKETDVEKVVRFARMWNVDLAFIGPEAPLEAGIVNALEREGIPTVGPTKEAARLETNKAWAREFMERNDIPGRKLFKVFDDVEEMKAWIDEYGKPVVVKPLGLTGGKGVKVVGYQLKDNEEAKEYAEYLIKKDGKVLIEERTDGVEFTFQVFSDGRNVIPMPLVQDYPHAYEGDVGPITGGMGSYSCSNHILPFITKEDWKMALRTLEETIKAMRKEGYPYKGILYGQFMLSREGPVIIEYNARFGDPEAINVLSILEDNLVEIAEGIVKGRVRGAKFQEKATVVKYLAPKGYPENPIRGAEIMVNEEAIKEEGAKIVYASVDENMKLLGSRALAMVGVADTLEEAEKIAEAGIRHVRGPVFYRKDVGTKESIEKRIRTMKELGKEFEPNSC
What are the official names of this protein?
Phosphoribosylamine--glycine ligase, GARS, Glycinamide ribonucleotide synthetase, Phosphoribosylglycinamide synthetase.
What is the protein family that this protein belongs to?
Belongs to the GARS family.
Protein: SYH_FRAP2
Sequence: MSKLTIIRGFNDILPQESCKWQFLESKIKSILDKYNYDEVRLPVLEKSELFHRSVGETSDIVSKETYDFVDRSGESLTLRPEGTAGCVRMVIENSLANRGQTQKLWYSGPMFRYERPQKGRYRQFYQLGVEAYGYDNIAIDLEILTISWNLFRELGISECVKLELNSLGSSSNRQEYTKALLEYLKPYHAQLDEDSIKRLDKNPLRILDSKNEQTQQVLANAPKLIDFIDEDSLTRFEQTCEYLDNLGVNYQVNQKLVRGLDYYSGLVFEWVTDRLGAQAAVCAGGRYDNLIESLGGQKAGAIGFAIGLERLLLLLESEGKLPIEDDKSDVFFILDNNQLHRSLLLVENVRQELPALKIDMDLKFGSFKSQFKKADKSDAKIAVIIGQDELLQQAVGVKYLQQDKQQEQIPLNKLINFLEKIAI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y1287_LACJO
Sequence: MAEQILVTTTENIPGRKYEIIGEVFGVTTQSKNAIRDFGAGLKSIVGGEIKAYTSMLTESRDQSIARLRQNASEMGANAVVMMRFDSGSIAGDMQSVVAYGTAVKFID
What are the official names of this protein?
UPF0145 protein LJ_1287.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: MFS11_PONAB
Sequence: MSPESKKLFNIIILGVAFMFMFTAFQTCGNVAQTVIRSLNSTDFHGSGYTSMAIIYGVFSASNLITPPVVAIVGPQLSMFASGLFYSMYIAVFNQPFPWSFYTASVFIGIAAAVLWTAQGNCLTINSDEHTIGRNSGIFWALLQSSLFFGNLYVYFAWQGKTQISESDRRTVFIALTVISLVGTVLFFLIRKPDSENVLGEDESSDDQDMEVNESAQNNLTKAVDAFKKSFKLCVTKEMLLLSITTAYTGLELTFFSGVYGTCIGAINKFGAEEKSLIGLSGIFIGIGEILGGSLFGLLSKNNRFGRNPVVLLGILVHFIAFYLIFLNMPGDAPIAPVKGTDSSAYIKSSKEVAILCSFLLGLGDSCFNTQLLSILGFLYSEDSAPAFAIFKFVQSICAAVAFFYSNYLLLHWQLLVMVIFGFFGTLSFFTVEWEAAAFVARGSDYRSI
What are the official names of this protein?
UNC93-like protein MFSD11, Major facilitator superfamily domain-containing protein 11.
What is the protein family that this protein belongs to?
Belongs to the unc-93 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RISB_SHESR
Sequence: MNVVQGNIEAKNAKVAIVISRFNSFLVESLLEGALDTLKRFGQVSDENITVVRVPGAVELPLAARRVAASGKFDGIIALGAVIRGGTPHFDFVAGECNKGLAQIALEFDLPVAFGVLTTDTIEQAIERSGTKAGNKGGEAALSLLEMVNVLQQLEQQL
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: RS14_ACTP7
Sequence: MAKQSMIARDVKRAKLADKFYAKREELKKIISDANSSDEDRWAAVLKLQTLPRDSSPSRQRNRCRQTGRPHGVLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: Y4794_BACC2
Sequence: MGFPKEGEKVQIHSYKHNGSIHRMWEETTILKGTQSLVIGANDRTVVTESDGRTWITREPAICYFHANYWFNVIGMLREDGVYYYCNLSSPFAYDSEALKYIDYDLDIKVYPDMTYTLLDEDEYEKHSQIMQYPPVIDTILKRNVAHLTQWIHQRKGPFAPDFVDMWYERYLMYRN
What are the official names of this protein?
UPF0374 protein BCG9842_B4794.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: ILVC_PROM5
Sequence: MTQLFYDTDADLSLLNNKTIAIIGYGSQGHAHALNLKDSGMDVIVGLYKGSKSESKAINDGLEVFTVSEACEKADWIMILLPDEFQKDVYIKEIEPNLKEGKILSFAHGFNIRFGLIKPPSFVDVVMIAPKGPGHTVRWEYQNGQGVPALFAVEQDYSSNARSLAMAYAKGIGGTRAGILETNFKEETETDLFGEQAVLCGGLSELVKSGFETLVEAGYQPELAYFECLHEVKLIVDLMVKGGLSQMRDSISNTAEYGDYVSGKRLINSDTKKEMQKILKDIQDGTFAKNFVEECDRDKPLMTKLRAENSQHEIEKVGKGLRAMFSWLK
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 1, Ketol-acid reductoisomerase type I.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.