PharMolix/UniProtQA huggingface dataset:
Protein: KAD_MICLC
Sequence: MTRMLLMGPPGSGKGTQATRIADKLGIVPISTGDIFRHNVKSMTPLGVEAKRYIDNGDFVPDEVTNRMVADRIAQADAEHGFLLDGYPRTKGQVEALDAMLAEAGQSLSAVVELEVPDEELVERLLKRAEIEGRADDTQEVIEHRLDLYHRETESVIQEYVERGIVARVDGTGQIDDVTERLLQAVYSVRSATGSLPVIQPGAES
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COQ42_CAEBR
Sequence: MSAQKLYGSHVPLAPLSRILLGIGSAATAITDPRRGDMVAAMGETTAVGPVLENIRRRMESDKIGKKLLMEKPRISNETIDRKWLAQLPDGTLGKHYSNFLERLNTSPDARPTVKYIDNLEHLYVMQRYRETHDFTHIALEQKTNMLGGSSSEIF
What are the official names of this protein?
Protein coq-4.2.
What is the protein family that this protein belongs to?
Belongs to the COQ4 family.
Protein: CBR2_MOUSE
Sequence: MKLNFSGLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKECPGIEPVCVDLGDWDATEKALGGIGPVDLLVNNAALVIMQPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMINRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVLTDMGKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLLSDRSASTSGGGILVDAGYLAS
What is the function of this protein?
May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism.
What are the official names of this protein?
Carbonyl reductase [NADPH] 2, Adipocyte protein P27, AP27, Lung carbonyl reductase, LCR, NADPH-dependent carbonyl reductase 2.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: H2A_DROHY
Sequence: MSGRGKGGKVKGKAKSRSNRAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: CRCB1_STRCO
Sequence: MTVPRTGRPGGIRAAAPSRSGWRTQAPVVAVVALGGGTGAAARYAASLWWPTPAGGFPWTTFGVNAVGCAVIGVFMVVITEVRPAHRLVRPFFGTGVLGGFTTFSTYAVDSRSLFADGRLPTGLAYLAATPLAALTAVWLAAWAARRVLKWRQS
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 1.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: UBIE_CERS5
Sequence: MNDETSNTTHFGFRTVPEGEKAGMVHGVFTRVASKYDIMNDLMSGGIHRLWKDAMMDWLAPRPGQKLLDVAGGTGDISFRFLKRAPGAHATVCDMTESMLVEGRQRADAAQMADRLDWVVGDAMALPFASNTFDVYTISFGIRNVTRVQDALNEAFRVLKPGGRLMVLEFSQLPNPAMQWAYDRYSFNVIPVMGQIVANDRDSYQYLVESIRKFPDQETFAGMIRKAGFGLVKYRNLSMGIAALHSGWKI
What is the function of this protein?
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
What are the official names of this protein?
Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE, 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, Demethylmenaquinone methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
Protein: 1A_CMVFN
Sequence: MATSSFNINELVASHGDKGLLATALVDKTAHEQLEEQLQHQRRGRKVYIRNVLGVKDSEVIRNRYGGKYDLHLTQQEFAPHGLAGALRLCETLDCLDSFPSSGLRQDLVLDFGGSWVTHYLRGHNVHCCSPCLGIRDKMRHAERLMNMRKIILNDPQQFDGRQPDFCTQPAADCKVQAHFAISIHGGYDMGFRGLCEAMNAHGTTILKGTMMFDGAMMFDDQGVIPELNCQWRKIRSAFSETEDVTPLVGKLNSTVFSRVRKFKTMVAFDFINESTMSYVHDWENIKSFLTDQTYSYRGMTYGIERCVIHAGIMTYKIIGVPGMCPPELIRHCIWFPSIKDYVGLKIPASQDLVEWKTVRILTSTLRETEEIAMRCYNDKKAWMEQFKVILGVLSAKSSTIVINGMSMQSGERIDINDYHYIGFAILLHTKMKYEQLGKMYDMWNASSISKWFAALTRPLRVFFSSVVHALFPTLRPREEKEFLIKLSTFVTFNEECSFDGGEEWDVISSAAYVATQAVTDGKILAAQKAEKLAEKLAQPVSEVSDSPETSSQTPDDTADVCGREREVSELDSLSAQTRSPITRVAERATAMLEYAAYEKQLHDTTVSNLKRIWNMAGGDDKRNSLEGNLKFVFDTYFTVDPMVNIHFSTGRWMRPVPEGIVYSVGYNERGLGPKSDGELYIVNSECVICNSESLSTVTRSLQAPTGTISQVDGVAGCGKTTAIKSIFEPSTDMIVTANKKSAQDVRMALFKSSDSKEACTFVRTADSVLLNECPTVSRVLVDEVVLLHFGQLCAVMSKLKAVRAICFGDSEQIAFSSRDASFDMRFSKIIPDETSDADTTFRSPQDVVPLVRLMATKALPKGTHSKYTKWVSQSKVKRSVTSRAIASVTLVDLDSSRFYITMTQADKASLISRAKEMNLPKTFWNERIKTVHESQGISEDHVTLVRLKSTKCDLFKQFSYCLVALTRHKVTFRYEYCGVLNGDLIAECVARA
What is the function of this protein?
Involved in the virus replication.  Contains a helicase domain and a methyltransferase domain.  The methyltransferase domain is probably involved in viral RNA capping.  Involved in the formation of ER membrane spherular invaginations in which RNA replication complexes form (By similarity).
What are the official names of this protein?
Replication protein 1a.
What is the protein family that this protein belongs to?
Belongs to the bromoviridae replication protein 1a family.
What are the subcellular locations of this protein?
Host endoplasmic reticulum membrane; Peripheral membrane protein.
Protein: LEPA_LEPBA
Sequence: MNERQKFTRNFSIIAHVDHGKSTLADRLLEIGLVTDKRTQKNQILDSMDIERERGITIKANNASFDYHAKDGNIYHLNLIDTPGHVDFTYEVSRSLAACEGVLLIVDASQGVEAQTLANLYLAMDLDLRIIPVINKIDLPSADIDKCKLMIEESLGLNPEEAIPISAKTGLNVQEVLEAICYLLPPPVGDVDAPLKALIYDSFFDTYMGVVAKVRLYDGRLKKGEMIHMMNIGRQFTVTEVGINRLSMVACEELQAGDVGYVVAGMKKMGDAKTGDTITHANRQTAEDVKGFKDAKPMVFAGLFPINGEDFDALVDAIEKLKLNDSALTFERENSAALGFGFRVGYLGLLHMEIVQERLEREFNLALITTAPSVKFRITTTKDEVIEVDNPSKWPDPILIGKSEEPFVKATIIAPESYVGNIMSLVIEKRGIHLDTVYLSKDKLQLTYELPLAELIFEFYDKLKSYTKGYASLDYEEVGYRDSKLVRMDILVNGEPVDALSSIVHKTKAEERGRVIIEKLKDLIPRHQFMIPLQAAIGSKVVARESISALRKNVTAKCYGGDISRKKKLLEKQKEGKKRMKQIGNVEIPQEAFLSILKTGD
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ALDR_RABIT
Sequence: MATHLVLYNGAKMPILGLGTWKSPPGQVTEAVKTAIDLGYRHIDCAHVYQNENEVGVALQEKLKEQVVKREELFIVSKLWCTSHDKSLVKGACQKTLNDLKLDYLDLYLIHWPTGFKHGSEYFPLDAAGNVIPSDTDFLDTWEAMEGLVDEGLVKSIGVSNFNHLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIADKHKKTTAQVLIRFPMQRNLVVIPKSVTPARIAENFQVFDFELSSEDMTTLLSYNRNWRVCALVSCASHKDYPFHAEF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols.  Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and xenobiotics substrates.  Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia.  Reduces steroids and their derivatives and prostaglandins.  Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal.  Catalyzes the reduction of diverse phospholipid aldehydes such as 1-palmitoyl-2-(5-oxovaleroyl)-sn -glycero-3-phosphoethanolamin (POVPC) and related phospholipid aldehydes that are generated from the oxydation of phosphotidylcholine and phosphatdyleethanolamides.  Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls).
What are the official names of this protein?
Aldo-keto reductase family 1 member B1, Aldehyde reductase, Aldose reductase, AR.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ALLA_SHIF8
Sequence: MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALVEILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDLSTLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
What is the function of this protein?
Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate.  Involved in the anaerobic utilization of allantoin as sole nitrogen source.  Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate.
What are the official names of this protein?
Ureidoglycolate lyase, Ureidoglycolatase.
What is the protein family that this protein belongs to?
Belongs to the ureidoglycolate lyase family.
Protein: Y448_RICPR
Sequence: MSEIITNINDSIEKIKKIEEITEISAAVQGKIIDIKNVDSRLDTLNKNIVILDPIQQYLQSEEYIISTLEVLASHIISEVVENKDVQKLVDNLHINLEQITKLIPSAADKLKFDIARAEAALKGFVLPLNNGGPFDELSLMGIKDKEEIFAGPIRATKKALIAISGNSIPKEQYANAIKDKAMEILKQDPNNTPDKLEQYEKFIIQGDKNQKFNKDSNQFIPRVNKLSQIEFKELQKAATDTVHKISSRLEKNNSISKQLEQIVLIANSSGIKKSKVIIKKLNKLDSTYLSENSTKIATALKDINDKGASLWEKFKQIFTGRNYLEERLSQLVDKHITLSDGYVVKTINDRIFSNALTNPEIAVGLTKFLNKNKDKVTTNPEFKNLIPITGEHIIVQPQQVNNLNLAELRKINPITFDKTIFEDSIKLRNSNRKYPQTTPNIATKNQEAVRSKG
What are the official names of this protein?
Uncharacterized protein RP448.
Protein: TRMJ_CROS8
Sequence: MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNASIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVSEATHAPVAIVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAWLASQDAQTPAPGEEETPYPLVDDLERFYGHLEQVLLSTGFIRPNHPGQVMNKLRRLFTRARPESQELNILRGMLASIESSRNEKP
What is the function of this protein?
Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
What are the official names of this protein?
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ, tRNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase, tRNA Cm32/Um32 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GCSP_LEPBJ
Sequence: MNSTLQNRNRTNLERVSTDPLDTFPRRHIGPDSQQVDKMLKSLGLSSLEELVDKAVPAGIRLKKEPDLPKASTEHKILQDLKNIASQNQIFRSYIGAGYNACIIPGVIQRNILENPGWYTAYTPYQAEISQGRLEALLNFQTMIIDLTGLEISNASLLDEGTAAAEAMFLAYSIRKNEIAKKFFVSELCHPQTIDVVVTRANPLGIEIVIGNHESVELNEDFFGVLLQYPATDGKIIDYTSFIQRAHNVGAISTVAADLLALTLLKSPGEMGADIAVGSSQRFGLPLGFGGPHAGYFATKDEFKRSMPGRLIGVSKDSQGNPGLRLSLQTREQHIRRDKATSNICTAQVLLAVISSMYAVYHGPEGLKDIATRIHKFTSILADALKSSGFTISNDTFFDTITIQAGAKAKDILNRARSERINLREYKDGRIGIALDETVNSDDIKDLFKIFEVKNTDIEKLFSNSGNISDSFKRSTSYLTHPVFQSFHTETKMLRYIRKLESRDLSLTTSMIPLGSCTMKLNATTEMYPVTWPEFGAIHPFAPSEQTKGYKIIFEQLEKWLCEITGFAGVSLQPNAGSQGEYAGLLAIRRYHESRKETHRNVCLIPISAHGTNPASAAMAGFKVVVVSCDQNGNVDLEDLKIKAEEHKNDLAALMITYPSTHGVFEESVKEICQIVHSRGGQVYMDGANMNAQVGLTSPGEIGADVCHLNLHKTFCIPHGGGGPGVGPIGVAKHLVPFLPGHVLVDNTTGNEHGAVSAAPWGSASIVLISWIYIALMGSEGLTNATRISILNANYIAKRLEKAYPVLYKGKNGFVAHECILDVRPFKKSAEIEVEDVAKRLIDYGFHAPTMSFPVPGTLMIEPTESESLEELDRFCEAMLLIHQEILDVQNGTLDKIDNPLKNSPHTAAMTTSDRWDHLYPKERAAYPAPWSRDHKFWPFVGRVDNVYGDRNLVCSCLPVESYQ
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
What are the official names of this protein?
Glycine dehydrogenase (decarboxylating), Glycine cleavage system P-protein, Glycine decarboxylase, Glycine dehydrogenase (aminomethyl-transferring).
What is the protein family that this protein belongs to?
Belongs to the GcvP family.
Protein: RIBJ_TRYB2
Sequence: MLPSFTRKPADHPIGYLVALSGLLMQLMSYGIDNSYSIFSEDMHNDPSLGFPSITAISLGNSVSLGLSPAFGVLAGFCVDRLPPRFMMALSTILLFTGLWISSTLAANIYVVTFTYCLFASIGTACMLSPGAAATSSWFNRYQGLAMGINFAGGGIGSAIIPPLAGKWVVAYGWRKAFQLMSIFCAIGVLATALSARRREPKRDDSSADDETREGNKSGNGSLVRRSNEPATVGGEGAANNGHNEGKEDVREMGRKNGSHTNTSKVPPNGRGVGTNQQNGNDGEGLDVTEQSQRNNTFASAIDVDMDTSMDADEPQVIRSLHTHKLTPWELFLSMFTLPFMGNFLCWFIYSWAFYSLIYAAVPYISSMGKPGTVYAGVPPIPTDVAATLFTFYGVFQVVGSVLVGWLASLVTAEFAYVFCATVGGIGCGLLALGRSYVAFALLLCIIGFCMAGMFAVMPTLIATHLYGPNLGFYFGAVFLAGVVGGFVAPPMQATIQLRNNGSYAFVCVVMSVSMTLSALVCYATLWRSKRSGIVLAARKTKLVEIM
What is the function of this protein?
Transporter involved in riboflavin (vitamin B2) uptake.  Also transports FMN and FAD.
What are the official names of this protein?
Riboflavin transporter RibJ, Riboflavin/flavin transporter.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. RibJ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RET4_XENLA
Sequence: MERKVLGLLIALGFLGSCLAEKNCRVDNFEVMKDFNKERYAGVWYAVAKKDPEGLFLLDNIAANFKIEDNGKTTATAKGRVRILDKLELCANMVGTFIETNDPAKYRMKYHGALAILERGLDDHWVVDTDYTTYAITYACRRRNLDGTCRDSYSFVFSRDINGLPSESQRIVRRRQEQLCLDRKYRVVVHNGYCETN
What is the function of this protein?
Retinol-binding protein that mediates retinol transport in blood plasma.  Delivers retinol from the liver stores to the peripheral tissues.  Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane.
What are the official names of this protein?
Retinol-binding protein 4, Plasma retinol-binding protein, PRBP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Lipocalin family.
What are the subcellular locations of this protein?
Secreted.
Protein: GIT2_MOUSE
Sequence: MSKRLRSSDVCADCNGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTAWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCREDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLIEIQYELTDRLAFYLCGRKPDHKSGQHFLIPQRADSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQGSPLSRSKDNVELILRTVSTQHSTESQDNDQPDYDSVASDEDTDVETRASKANRQKLQTLQSENSSLRRQATASACQVQTGSDHKDTASHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEASHPEESRTRLQPFPTHIGRSALVTSSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTACDPEPDDTGSTRKGRQRSMLWQGDGLLPDTAEPHSVPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDTVRTSLRLLTSSAYRLQSECRKALPGDSSLPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENSS
What is the function of this protein?
GTPase-activating protein for ADP ribosylation factor family members, including ARF1.
What are the official names of this protein?
ARF GTPase-activating protein GIT2, ARF GAP GIT2, Cool-interacting tyrosine-phosphorylated protein 2, CAT-2, CAT2, G protein-coupled receptor kinase-interactor 2, GRK-interacting protein 2.
Protein: CIN_DROME
Sequence: MESITFGVLTISDTCWQEPEKDTSGPILRQLIGETFANTQVIGNIVPDEKDIIQQELRKWIDREELRVILTTGGTGFAPRDVTPEATRQLLEKECPQLSMYITLESIKQTQYAALSRGLCGIAGNTLILNLPGSEKAVKECFQTISALLPHAVHLIGDDVSLVRKTHAEVQGSAQKSHICPHKTGTGTDSDRNSPYPMLPVQEVLSIIFNTVQKTANLNKILLEMNAPVNIPPFRASIKDGYAMKSTGFSGTKRVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQLDKNGQESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLILSKPKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLEDLQFRIHCGRVNIKPGKPMTFASRKDKYFFGLPGNPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDFSLDSRPEFVRASVISKSGELYASVNGNQISSRLQSIVGADVLINLPARTSDRPLAKAGEIFPASVLRFDFISKYE
What is the function of this protein?
Catalyzes two steps in the biosynthesis of the molybdenum cofactor.  In the first step, molybdopterin is adenylated.  Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
What are the official names of this protein?
Molybdenum cofactor synthesis protein cinnamon.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the MoeA family.
Protein: ETFA_PONAB
Sequence: MFRAAAPGQLRRAASLLRFQSTLVIAEHADDSLAPITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCKVAGIAKVLVAQHDVYRGLLPEELTPLILATQKQFNYTHICAGASAFGKNLLPRVAAKLEVAPISDIIAIKSPDTFVRTIYAGNALCTVKCDEKVKVFSVRGTSFEAAATSGGSASSEKASSTSPVEISEWLDQKLTKSDRPELTGAKVVVSGGRGLKSGENFKLLYDLADQRHAAVGASRAAVDAGFVPNDMQVGQTGKIVAPELYIAVGISGAIQHLAGMKDSKTIVAINKDPEAPIFQVADYGIVADLFKVVPEMTEILKKK
What is the function of this protein?
Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase.  It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).  Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism.
What are the official names of this protein?
Electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF.
What is the protein family that this protein belongs to?
Belongs to the ETF alpha-subunit/FixB family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: MURA_ACIF5
Sequence: MDKLLLRGNGPLRGELRISGAKNAALPCLAATLLAREPVRLCNIPHLRDITTTLELLSTLGARVLVDGQLGIEVDPRPVHSVVAPYELVKTMRASILVLGPLLARHGSAEVSLPGGCAIGSRPVSVHLSGLQALGAEITVEDGFVKAQAARLRGTRIVMEMVSVTGTENLLMAATLAEGRTILENAAREPEIVDLARCLSAMGARISGAGTSVIEIEGVAELHGAEHSVVPDRIETGTYLVAAAMTGGDICLKRTDAGLLESVLLKLKEAGAEVTTGADTIRIRMKRRPRAVDVRTAPFPAFPTDMQAQFMAMNCIAEGSSVVTETIFENRFMHVSELQRLGADINADGKTAVVRGVQRLRGAPVMATDLRASASLVLAGLVAEGETLIDRIYHLDRGYEVIEEKLSALGADIRRISNTRSVA
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HRD3A_ARATH
Sequence: MRILSYGIVILSLLVFSFIEFGVHARPVVLVLSNDDLNSGGDDNGVGESSDFDEFGESEPKSEEELDPGSWRSIFEPDDSTVQAASPQYYSGLKKILSAASEGNFRLMEEAVDEIEAASSAGDPHAQSIMGFVYGIGMMREKSKSKSFLHHNFAAAGGNMQSKMALAFTYLRQDMHDKAVQLYAELAETAVNSFLISKDSPVVEPTRIHSGTEENKGALRKSRGEEDEDFQILEYQAQKGNANAMYKIGLFYYFGLRGLRRDHTKALHWFLKAVDKGEPRSMELLGEIYARGAGVERNYTKALEWLTLAAKEGLYSAFNGIGYLYVKGYGVDKKNYTKAREYFEKAVDNEDPSGHYNLGVLYLKGIGVNRDVRQATKYFFVAANAGQPKAFYQLAKMFHTGVGLKKNLEMATSFYKLVAERGPWSSLSRWALEAYLKGDVGKALILYSRMAEMGYEVAQSNAAWILDKYGERSMCMGVSGFCTDKERHERAHSLWWRASEQGNEHAALLIGDAYYYGRGTERDFVRAAEAYMHAKSQSNAQAMFNLGYMHEHGQGLPFDLHLAKRYYDESLQSDAAARLPVTLALASLWLRRNYADTVLVRVVDSLPEVYPKVETWIENVVFEEGNATILTLFVCLITILYLRERQRRQVVVVADPVAADVAQPLDADVAQHLAAFPR
What is the function of this protein?
Component of the endoplasmic reticulum (ER) quality control system called ER-associated degradation (ERAD) and involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins.  Functions as an ERAD substrate-recruiting factor that recognizes misfolded proteins for the HRD1 E3 ubiquitin ligase complex.  Targets the misfolded LRR receptor kinase BRI1.
What are the official names of this protein?
ERAD-associated E3 ubiquitin-protein ligase component HRD3A, AtSel1A, Protein EMS-MUTAGENIZED BRI1 SUPPRESSOR 5.
What is the protein family that this protein belongs to?
Belongs to the sel-1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Single-pass membrane protein.
Protein: H_BPCHP
Sequence: MSFAENVGRFIGNSVNSVGSVIGDGLKGFNSTQSISSAKQANLLNNLPLPSLDNVLNIGMFGGLASGLLSYRAAKKQNKVMQDIANRQMAFQERMSSTAVRRHVEDLKKAGLNPLLALGGSASTPQGAFYSPVNPMESGLNSAISVADKVFDYQRLAHADFQGRLNSAMSVVQLASAVQDYKRNYGKFGEVAYWFDRYAGKLLPAMLFYLFRKHPVGRAVSAANSGYAVAKGAKGVNFKFSNMSSTAVQRHNSRYNVSKGWRR
What is the function of this protein?
Probably triggers with protein G the injection of the phage DNA into the host upon conformational changes induced by virus-host receptor interaction.
What are the official names of this protein?
Minor spike protein H, H protein, Pilot protein, Protein VP2, VP2.
What is the protein family that this protein belongs to?
Belongs to the microviridae H protein family.
What are the subcellular locations of this protein?
Virion.
Protein: RS17E_SACS2
Sequence: MGNIYTKDIKRIVKEIYDRYKDEIKDDYNTNKQIVIRYVDVKSKKVRNRIAGYLTRYYKIMKEKETSPAEEKEEISEEI
What are the official names of this protein?
30S ribosomal protein S17e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eS17 family.
Protein: NUOK_SHIBS
Sequence: MIPLQHGLILSAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit K, NADH dehydrogenase I subunit K, NDH-1 subunit K.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: H2B2E_MOUSE
Sequence: MPELAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIANEASRLAHYNKRSTITSREIQTSVRLLLPGELAKHAVSEGTKAVTKYTSAK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B type 2-E, H2B-clustered histone 21, H2b 613.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: TRPD_ANADE
Sequence: MIQHAIAKLLEGEDLSRAEAAQVMTEIADGGATPAQSGAFLAALRMKGETVEEIAGAADVMRQRADRVRVSRDVFIDTCGTGGDGRHTFNISTTAAFVAAGAGVCVAKHGNRAVSSRSGSADVLAALGVNVDADKETVERCIEEVGIGFLFAVRLHPAFKAIAGVRRELGVRTIFNLLGPLANPAGARHQVLGVYEARWVPVLGGVLAALGAAHAFVVHGEGLDEIAVTGMTHVCEVKDGAVERYTIRPEDLGLPRRDAAELAGGDAAANARIVTHVLEGQQGGPRDAVLANAAAALVCAGAATDLRDGVARAARSIDSGAAREKLRQLVAATTVPA
What is the function of this protein?
Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
What are the official names of this protein?
Anthranilate phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the anthranilate phosphoribosyltransferase family.