PharMolix/UniProtQA huggingface dataset:
Protein: SPDE_COFAR
Sequence: MADAVNSNSKEEAAQLPDGVSSVIPGWFSEISPMWPGEAHSLKVEKILFQGKSDYQNVMVFQSSTYGKVLVLDGVIQLTERDECAYQEMIAHLPLCSIPSPKKVLVIGGGDGGVLREVARHLSVEQIDICEIDKMVVDVSKQFFPDVAVGFEDPRVVLHIGDGVAFLKAVPEGTYDAIIVDSSDPIGPAQELFEKPFFESVAKALRPGGVVCTQAESIWLHMHIIEDIVANCRQIFKGSVNYAWTTVPTYPSGVIGFMLCSTEGPPVDFKHPINPIDANDGRSKTMKPLKFYNSEIHSAAFCLPSFAKKVIDSKAN
What are the official names of this protein?
Spermidine synthase, SPDSY, Putrescine aminopropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the spermidine/spermine synthase family.
Protein: TAL_BUCA5
Sequence: MNQLSALKQFSIIVADTSDIKSICKYQPEDATTNPSLILQAVSSNTNQNFVDQAVQYAKKKGGLYKDQIINASDKILVDLGIEILKKIPGYISSEVDARLSFSTEASILKAKKIIDLYEEQGISRNRVLIKLAATWECIKAAEELKKDSILCNLTLLFSFAQARACAESNVFLISPFVGRIYDWYISQNLLSKSFLGKDPGVISVCKIYEYYKKYGYKTIIMGASFRNIQQILYLSGCDRLTISPVLLKELESNTAKIDRNLAPPSFISVPPVALSEEEFRWEHNQDAMAVQKLSDGIRNFGKDQLRLEKIFSKKI
What is the function of this protein?
Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
What are the official names of this protein?
Transaldolase.
What is the protein family that this protein belongs to?
Belongs to the transaldolase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZNTD_DICDI
Sequence: MGISLSVLDIKIISTTVLFILSLLAGIAPYWMRNLNNSSRYLSWSNTFAGGVFFGAGMLHLFATADEDLQPYVQKYNYPFAALCLCVGFLITLFLELIINSIFIKSNTFASLHGHSHSHVHLSHGHSHHGKDNGSNGNPGSGVGIGMGSVGALNSKKNKTTSPTITPTTPSEGTTTTTTTTTATTAATAKEIVLEDEDEDEEKDIMDEIIIPDDYDENDDEQIYKKKQSKCARTKFRKFIDTIPTFSSTSTSSTSSSTKISEKQRLLDSSNSYYYNQNKYKGIIGSHIDIDKSGSGVGGFSNNNNNNNNNNNNNNKNNNNNNNNNFRTEIIIQPISTTSNNSVHHYPSSSVNYHPFITTTTTTCSNDNSNSNNNNSSNNNSSSANITPNTNKILSSSKSLSYRYNGDDEEPDIIIDYDDIDYNQEGRTRGNSLGSDSNVHNERIVLINSGIGNSGNIGSNNNNNNNGGGGGGGGNSNIDYNDNEENNNNNNKIESEILIKDTTTDSIKNMKGGEHQHQHLHQQEIIVVTKKSNILLPFILVIALSIHSLFEGLAMGVQSSEIRVFDILIAIFAHKILASFALGISTITSSNEKPSFLKLFLLVFVFSLTSPIGSILGMVIVGSGVTGSMVPPILQGIASGTFLYVAVVEIIPKELSHDSNDILIKSFLLLLGFSGMAVVAIWV
What is the function of this protein?
May transport divalent cations (By similarity).  May participate, with dstA, in the regulation of the differentiation of stalk cells during development.
What are the official names of this protein?
Protein zntD.
What is the protein family that this protein belongs to?
Belongs to the ZIP transporter (TC 2.A.5) family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: RK5_STIHE
Sequence: MTQRLSKLYFEQISPKLIEKFSYKNMHQVPRVEKIVINRGVGEAAQSNKVLESSLKELNLISGQKGIITRSKKAIAGFKIREKVPVGVFVTLRGDRMYSFLDRLINLALPRIRDFQGISAQSFDKYGNYSLGLEEQLMFPEIEYDKIDQLRGMDISIVTNARNSEEGLALLKEFGLPFKS
What is the function of this protein?
Binds 5S rRNA, forms part of the central protuberance of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L5, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ACP_CROS8
Sequence: MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELVMALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: STX3_CAEEL
Sequence: MPRDRLKELQEKATVNTIHAYNYDPPARKYDVESQPLINQDADFEMFLERCSNIRGGLKSLEEDYDAVVQLHGALLSTPGADSENSNKLKSHNQMFFSKAEQIKNSLKILSEETSRIPTTACGIMRAKSDQVKSIYKTFENIMLNFNREQDEYKEKAKRKIVDYLKIRNMQLSDEEIENAVSSGNLSEVTKGVMLALNEKKALYDEVKSRADELKNLERQMGELAQMFHDLHIMVVSQAKMVDSIVNSVENATEYAKQARGNVEEARNLQKRARKMKVCIIIGSIIAVLILILFIQSAVCHFTPIC
What is the function of this protein?
Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity).  Acts in the intestine to regulate anterior body muscle contractions (aBOC) and the expulsion steps during the defecation motor program (DMP).
What are the official names of this protein?
Putative syntaxin-3.
What is the protein family that this protein belongs to?
Belongs to the syntaxin family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type IV membrane protein.
Protein: DCYD_SALTI
Sequence: MPLHHLTRFPRLELIGAPTPLEYLPRLSDYLGREIYIKRDDVTPIAMGGNKLRKLEFLVADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPDAQLQTLATRIEAQGFRPYVIPVGGSSALGAMGYVESALEIVQQCEEVVGLSSVVVASGSAGTHAGLAVGLEHLMPDVELIGVTVSRSVAEQKPKVIALQQAIAGQLALTATADIHLWDDYFAPGYGVPNDAGMEAVKLLANLEGVLLDPVYTGKAMAGLIDGISQKRFNDDGPILFIHTGGAPALFAYHPHV
What is the function of this protein?
Catalyzes the alpha,beta-elimination reaction of D-cysteine and of several D-cysteine derivatives.  It could be a defense mechanism against D-cysteine.
What are the official names of this protein?
D-cysteine desulfhydrase.
What is the protein family that this protein belongs to?
Belongs to the ACC deaminase/D-cysteine desulfhydrase family.
Protein: AT7L3_HUMAN
Sequence: MKMEEMSLSGLDNSKLEAIAQEIYADLVEDSCLGFCFEVHRAVKCGYFFLDDTDPDSMKDFEIVDQPGLDIFGQVFNQWKSKECVCPNCSRSIAASRFAPHLEKCLGMGRNSSRIANRRIANSNNMNKSESDQEDNDDINDNDWSYGSEKKAKKRKSDKNPNSPRRSKSLKHKNGELSNSDPFKYNNSTGISYETLGPEELRSLLTTQCGVISEHTKKMCTRSLRCPQHTDEQRRTVRIYFLGPSAVLPEVESSLDNDSFDMTDSQALISRLQWDGSSDLSPSDSGSSKTSENQGWGLGTNSSESRKTKKKKSHLSLVGTASGLGSNKKKKPKPPAPPTPSIYDDIN
What is the function of this protein?
Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination.  Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879).  The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription.  Required for nuclear receptor-mediated transactivation.  Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972).  Regulates H2B monoubiquitination (H2Bub1) levels.  Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583).
What are the official names of this protein?
Ataxin-7-like protein 3, SAGA-associated factor 11 homolog.
What is the protein family that this protein belongs to?
Belongs to the SGF11 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: YL908_MIMIV
Sequence: MRRTCCLFNSLDSTTRIVPNAIRINHTNSMSLRTSTVSTSTKMFTKHAKNRIGNSIRLRDELYQNYLKNYKKIQLYKKSQPPKKIEYEFVLDILFYGSCAIVFYAICEKIHDRKIRRSLVKEDFSDYPYHGL
What are the official names of this protein?
Uncharacterized protein L908.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RL15_ACIB5
Sequence: MTLRLNELAPAEGAKREHRRLGRGIGSGVGKTGGRGIKGQKSRKSGGVRPGFEGGQTAIYRRLPKFGFTSQIALKTAEVRLSELSKVEGDIVSLETLKAANVVRRDQIRARIVLSGEITRAFTVQGVALTKGAKAAIEAAGGKVEE
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL15 family.
Protein: RNPA_MARMS
Sequence: MTEYCFPRHVRLLNAGDYQSVFNDTSSKVFAGEFLLLARKRDDDQTRLGLIVSKKTDKRAVGRNRIKRLVRDSFRHHKIPLSGLDIVFLARHGIKELENADLHNRLDKAWDQLAKKALKPTQNKKRDQSRQK
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: CORZ_DROER
Sequence: MLRLLLLPLFLFTLSMCMGQTFQYSRGWTNGKRSFNAASPLLTTGHLHRGSELGLSDLYDLQEWTSDRRLERCLSQLQRSLIARNCVPGSDFNANRVDPDPESSAHPRLGNINNENVLYSSANVPTRHRQSNELLEELSAAGGASAEPNVFGKH
What is the function of this protein?
Cardioactive peptide.  Corazonin is probably involved in the physiological regulation of the heart beat.  Clock (Clk) and cycle (cyc) proteins negatively regulate Crz transcription in a cell-specific manner (By similarity).
What are the official names of this protein?
Pro-corazonin, Crz, De-Crz.
What is the protein family that this protein belongs to?
Belongs to the corazonin family.
What are the subcellular locations of this protein?
[Corazonin]: Secreted. SUBCELLULAR LOCATION: [Corazonin precursor-related peptide]: Secreted.
Protein: GLMM_BIFA0
Sequence: MPRMFGTDGVRGLANRDLTAQLALDLGDAAVRVLGDDGGRETNRHRALIGRDTRVSGDFLSHALAAGMSAGGFDVIDAGIIPTPGVAFLTSVLNVEMGAVISASHNPMPDNGIKFFARGGFKLPDTKEDEIEAVLGQDWERPTGAGVGRVSHDTTTATNLYIDHLVSAIAPEGNEQPLKGLKVVADCANGATSVVAPEALRRAGADVIVINASPDGYNINKNAGSTHPESMQAMVRASGADLGVAFDGDADRCLAADAEGNMVNGDQIMGILARAKKREGKLNHDTLVVTVMSNLGLKLALKEMGIDTVQTNVGDRYVLEEMLRGDYSLGGEQSGHVINREFATTGDGTLTALTLCNEVVKSGKSLKELAADFPQLPQQLINVPNVDKMAAKTNKAVLEAVAREEELLGDTGRVLLRPSGTEPLVRVMAEAATQEQADEVTARLAQIVADELAL
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: RLME_BRUC2
Sequence: MSKAGGNKGGSRTGGRGGAGSSNLHVRVKKKAGTIKESSRRWLERHLNDPYVHKSRQDGYRSRAAYKLIEINDRYNLLKKGQKIIDLGAAPGGWSQIAARIVGSTDENPQVVGIDYLHVDPLPGVILLEMDFLDDEAPQKLMDALGDKPDLVISDMAAPTTGHRRTDHLRTVHLCEVAADFAVSVLKPGGHFLTKTFQGGTENELLALLKQKFRSVHHVKPPASRAESVELYLLARDFKG
What is the function of this protein?
Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase E, 23S rRNA Um2552 methyltransferase, rRNA (uridine-2'-O-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABPL_LITCT
Sequence: MAFSGIWNVYSQENYEPFLKAVGVPDDIIKVAKDIKPVIEIQQNGNDFVVTLKTPKNSQSNSFTVGQEAEITSAGGKKFKVTVNLEGGKLICKSDTFSHIQEVNGDEMVEQITIGSTTLIRKSKRS
What is the function of this protein?
Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm.  May be involved in intracellular lipid transport (By similarity).
What are the official names of this protein?
Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_GLUDA
Sequence: MPGRSRRRRELDRTEKREFVASLAAVFAETSMVVVTRNDGLTVADATILRQRVRAAGATYKVAKNRLANLALAGTRFEGISPLLKGPTALSWSADPVAVAKVLVEFAKTNEKLVLLGGALGTQTLNVDGVKALAELPSLDTLRAQLVGLISTPATRIAGVLQAPAGQLARVFGAYAKKDEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: P2C80_ARATH
Sequence: MSATALSRLNPVSQFGFQRIVAGKSKSFFSNSGQRRLFSDSSRFRQAMAASGSLPVFGDACLDDLVTTCSNGLDFTKKRSSGGSFTINCPVASMRLGKRGGMMKNRLVCHYSVVDPLEKSRALFGTLSKSVHTSPMACFSVGPAHELSSLNGGSQESPPTTTTSLKSLRLVSGSCYLPHPEKEATGGEDAHFICDEEQAIGVADGVGGWAEVGVNAGLFSRELMSYSVSAIQEQHKGSSIDPLVVLEKAHSQTKAKGSSTACIIVLKDKGLHAINLGDSGFTVVREGTTVFQSPVQQHGFNFTYQLESGNSADVPSSGQVFTIDVQSGDVIVAGTDGVYDNLYNEEITGVVVSSVRAGLDPKGTAQKIAELARQRAVDKKRQSPFATAAQEAGYRYYGGKLDDITAVVSYVTSS
What are the official names of this protein?
Probable protein phosphatase 2C 80, AtPP2C80.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
Protein: SPI2A_VACCC
Sequence: MKGENVFISPASISSVLTILYYGANGSTAEQLSKYVETEENTDKVSAQNISFKSINKVYGRYSAVFKDFFLGKIGDKFQTVDFTDCRTIDAINKCVDIFTEGKINPLLDEPLSPSN
What are the official names of this protein?
Putative serine proteinase inhibitor 2 homolog first part.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Poxviruses subfamily.
Protein: PCP_STRP3
Sequence: MKILVTGFDPFGGEAINPALEAIKKLPATIHGAEIKCIEVPTVFQKSADVLQQHIESFQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPIRVDGKAAYFSTLPIKAMVAAIHQAGLPASVSNTAGTFVCNHLMYQALYLVDKYCPNAKAGFMHIPFMMEQVVDKPNTAAMNLDDITRGIEAAIFAIVDFKDRSDLKRVGGATH
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTNP_BACSU
Sequence: METMKIGNITLTWLDGGVTHMDGGAMFGVVPKPLWSKKYPVNEKNQIELRTDPILIQKDGLNIIIDAGIGYGKLTDKQKRNYGVTQESNVKPSLAALGLTVADIDVIAMTHLHFDHACGLTEYEGERLVSVFPNAVIYTSAVEWDEMRHPNIRSKNTYWKENWEAVAGQVKTFEDTLTITEGITMHHTGGHSDGHSVLICEDAGETAVHMADLMPTHAHRNPLWVLAYDDYPMTSIPQKQKWQAFAAEKDAWFIFYHDAEYRALQWEEDGSIKKSVKRMKR
What is the function of this protein?
Probable hydrolase that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus.  Thus, serves as a defensive strategy against competing bacteria.  The putative target for YtnP may be a gamma-butyrolactone termed A factor, which is the quorum-sensing signaling molecule that positively regulates streptomycin production and development of aerial hyphae in S. griseus.
What are the official names of this protein?
Probable quorum-quenching lactonase YtnP.
What is the protein family that this protein belongs to?
Belongs to the metallo-beta-lactamase superfamily.
Protein: MDH_CITBB
Sequence: MARKKIALIGGGQIGGVLAQLAALRELGDVVMFDIVEGLPQGKMLDIAEVGSVDGFDCNLKGTNSYEDIKGADVVIVTAGLPRKPGMSRDDLIEVNSKIMTSVAEGIKANAPNAFVIVISNPLDAMVTLCQKITGFPYNRVIGQAGVLDSARFKTFIAWELGVSVKDVNAMTLGGHGDDMVPLVRYASVNGIPVMELLEKKYKDKAKAKEVMEAMVKRTRGAGGEVVALLKTGSAFYSPASSAIQMAESILKDQKRVLPTCAHLNGEFGVKGFYVGVPCVLGENGVEQILEFELDAEEQAMMDKSVAAVKELVGSMK
What is the function of this protein?
Catalyzes the reversible oxidation of malate to oxaloacetate.
What are the official names of this protein?
Malate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. MDH type 3 family.
Protein: CYP8_YEAST
Sequence: MKSFFLYLYVAFMFSCITALPLPVDNKRASSDSLDLKKKYAPDPPITHNVNIGIVFTDPESSEEAGRLITIDLYGTMVPKTVMTFCQYVDSVKDRLASRHSYSPERDFDKILPNGAIEGSSVSSSSIEETEMLAPKLPEENHSLIHDRPGRVSMIKDDKGLKFIIETSETPLEGESVVFGQVTAGLKDLMDKLANVKTDENGKPEQPITIGYISSQEHRIQHAKEAHEKYLQRLQDYQNGDLEKGITLKNYLYQGSQRKLEDAKYNQLHHPLPKIMLGISVLLLFYVLAKYRKRIFNRSSKIVSIRED
What is the function of this protein?
PPIases accelerate the folding of proteins.  It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase CYP8, PPIase CYP8, Rotamase CYP8.
Protein: IORF_CVMA5
Sequence: MESSRRPLGLTKPSVDQIIKIEAEGISQSRLQLLNPTPGVWFPITPGFLALPSSKRERSFSLQKDKECLLPMESPLQSKRDIGIDTTAVLLKHLMGSRSNYCPDGIFTILAQGPMLEPVMETALKVSSGLQTAKRTPIPALILSKGTQAVMRLFLLGLRPARYCLRAFMLKALEGLHLLADLVRGHNPVGQIIALEAVPTSASLPLL
What is the function of this protein?
Structural protein that is not essential for the viral replication either in tissue culture or in its natural host.  Confers a small growth advantage.
What are the official names of this protein?
Protein I, Accessory protein N2, N internal ORF protein, IORF, Protein in nucleocapsid ORF.
What is the protein family that this protein belongs to?
Belongs to the coronavirus I protein family.
What are the subcellular locations of this protein?
Virion.
Protein: PYRB_PSEAE
Sequence: MPTDAKRPLQLNDQGQLRHFISLDGLPRELLTEILDTADSFLEVGARAVKKVPLLRGKTVCNVFFENSTRTRTTFELAAQRLSADVISLNVSTSSTSKGETLTDTLRNLEAMAADMFVVRHSDSGAAHFIAEHVSPNVAVINGGDGRHAHPTQGMLDMLTIRRHKGNFEQLSVAIVGDILHSRVARSNMLALKTLGCPDIRVIAPRTLLPIGLEEQYGVRVFTNADEGLKDVDVVIMLRLQRERMQGGLLPSEGEFFKLYGLTEKRLKLAKPDAIVMHPGPINRGVEIESAVADGAQSVILNQVTYGIAIRMAVLSMAMSGQNTQRQLEQEDAE
What are the official names of this protein?
Aspartate carbamoyltransferase, Aspartate transcarbamylase, ATCase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: Y6073_MYCS2
Sequence: MAGNSQRRGAVRKPGTKKGPTVGSGGVRRRGLEGRGATPPAHMRPNHPAAKKARAAAKAQQQRAGRKADETELVLGRNPVLECLRAKVPATALYVALGTDADERVTESVQIAADRGISILEVPRTDLDRMSNHGLHQGLGLQVPPYAYAHPDDLLATARADAAPALLVALDNISDPRNLGAIVRSVAAFAGHGVVIPQRRSASVTAVAWRTSAGAAARVPVARATNLNRTLKSFADAGLQIVGLDAGGDTTLDELDATGPTVVVVGSEGKGLSRLVREHCDAIVSIPMAGPTESLNASVAAGVVLAEIARQRRS
What are the official names of this protein?
Uncharacterized tRNA/rRNA methyltransferase MSMEG_6073/MSMEI_5913.
What is the protein family that this protein belongs to?
Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
Protein: DCDB_SALTO
Sequence: MLLSDRDLAAEIKAGTLALEPFDPALVQPSSIDVRLDKLFRVFNNHLYTHIDPSRQQDDLTSAVEVPDGEPFVLHPGEFVLASTLEVISLGDQLAGRLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNVANLPIMLWPGMKIGQLCIFRLCSPAEHPYGSAVYGSRYQGQRGPTPSRSWQSWRTWPTR
What is the function of this protein?
Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.
What are the official names of this protein?
dCTP deaminase, dUMP-forming, Bifunctional dCTP deaminase:dUTPase, DCD-DUT.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: EPN1_HUMAN
Sequence: MSTSSLRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASSAAVGSGPPPEAEQAWPQSSGEEELQLQLALAMSKEEADQPPSCGPEDDAQLQLALSLSREEHDKEERIRRGDDLRLQMAIEESKRETGGKEESSLMDLADVFTAPAPAPTTDPWGGPAPMAAAVPTAAPTSDPWGGPPVPPAADPWGGPAPTPASGDPWRPAAPAGPSVDPWGGTPAPAAGEGPTPDPWGSSDGGVPVSGPSASDPWTPAPAFSDPWGGSPAKPSTNGTTAAGGFDTEPDEFSDFDRLRTALPTSGSSAGELELLAGEVPARSPGAFDMSGVRGSLAEAVGSPPPAATPTPTPPTRKTPESFLGPNAALVDLDSLVSRPGPTPPGAKASNPFLPGGGPATGPSVTNPFQPAPPATLTLNQLRLSPVPPVPGAPPTYISPLGGGPGLPPMMPPGPPAPNTNPFLL
What is the function of this protein?
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).  Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity).  Regulates receptor-mediated endocytosis (PubMed:10557078, PubMed:10393179).
What are the official names of this protein?
Epsin-1, EH domain-binding mitotic phosphoprotein, EPS-15-interacting protein 1.
What is the protein family that this protein belongs to?
Belongs to the epsin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein. Nucleus. Membrane, clathrin-coated pit. Note=Associated with the cytoplasmic membrane at sites where clathrin- coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145 (By similarity).
Protein: SECB_IDILO
Sequence: MAEEQQANGAAAENQQQQVQFAIQRIYAKDISFETPSSPAIFRKEWKPDLKLDLNVKHEKIEDGVYEVVLTLTATNKVEDDVAFLCEVHQAGIFTIGEEVQDGQLAHMLGSFCPNILFPYARECVSNLVNRATFPQLNLAPVNFDAIFQRHMQQQAEQAQGQQTADA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y213_ATV
Sequence: MDEKRVYITMYIKFAQKVLSLLSLKYASQKSVETYLYMFLYFGLGLRRNVTTLSLSQFDAKNLRFYPRPYAIYNDSPLYMIVPRHLVDIIVLYTRRFKIGLDQPLFRDIERPSVYERKIFEITGILPQDLVNACIATMIEYSKNPKQVARLLYLNKVYLDFIVRKLGFKLTNDFKLMTADGRILEPSPEVLHPFLYLAKKTKQQQEQGAGSLA
What are the official names of this protein?
Uncharacterized protein ORF213.
Protein: T23O_DROMO
Sequence: MSCPYASNGNEHDDGAIPLSNEVGKIYGEYLMLDKLLDAQCMLSMEDKRPVHDEHLFIITHQAYELWFKQIIFEFDSIRDMLDAEVIDETKTLEIVKRLNRVVLILKLLVDQVPILETMTPLDFMDFRKYLAPASGFQSLQFRLIENKLGVLTEQRVKYNQKYTDVFGNDKKALHAIRDSEDSPSLLTLVQRWLERTPGLEEDGFNFWAKFQQSVDQFLAAQVQSAMLEPVERAKNYRLMDIEKRREVYRSIFDPAVHDALVKRGDRRFSHRALQGAIMITFYRDEPRFSQPHQLLTLLMDIDSLITKWRYNHVIMVQRMIGSQQLGTGGSSGYQYLRSTLSDRYKVFLDLFNLSTFLIPREAIPPLDETIRRKLIHKSV
What is the function of this protein?
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine.  Catalyzes the oxidative cleavage of the indole moiety.
What are the official names of this protein?
Tryptophan 2,3-dioxygenase, TDO, Protein vermilion, Tryptamin 2,3-dioxygenase, Tryptophan oxygenase, TO, TRPO, Tryptophan pyrrolase, Tryptophanase.
What is the protein family that this protein belongs to?
Belongs to the tryptophan 2,3-dioxygenase family.
Protein: PTC1_LEPLD
Sequence: GLVNGLLSSVLGGGQGGGGLLGGIL
What is the function of this protein?
May play an immunomodulatory role in frog skin in response to microbial pathogens, since it increases the production of the pro-inflammatory cytokines TNF-alpha, IL-1 beta, IL-12, and IL-23 by mouse peritoneal macrophages and has no effect on the production of the anti-inflammatory cytokine IL-10 (PubMed:24073891).  It is not known whether stimulation of cytokine production arises from a non-specific interaction of the peptide with the macrophage membrane or from interaction with a specific receptor (Probable).  Shows a low activity in stimulating insulin release from rat BRIN-BD11 beta cells, and acts without loss of integrity of the plasma membrane (PubMed:19428765).  Shows a marked affinity for both neutral and anionic membranes models (PubMed:24073891).  Does not show antibacterial (E. coli and S. aureus) (PubMed:19428765).  Does not show hemolytic activity against human erythrocytes (PubMed:19428765).
What are the official names of this protein?
Plasticin-L1, PTC-L1.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Plasticin subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Forms a helical membrane channel in the target.
Protein: NDK_DINSH
Sequence: MAIERTLSIIKPDATKRNLTGKINAKFEDAGLRIVAQKRIHLTKAQAGVFYAVHAERPFYDELCEFMASEPVVVQVLEGEGAIAKNREVMGATNPADAAPGTIRAEFAESVGENSVHGSDAPETAAVEIAYFFSGLELVG
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.