PharMolix/UniProtQA huggingface dataset:
Protein: IGLC7_HUMAN
Sequence: GQPKAAPSVTLFPPSSEELQANKATLVCLVSDFNPGAVTVAWKADGSPVKVGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCRVTHEGSTVEKTVAPAECS
What is the function of this protein?
Constant region of immunoglobulin light chains.  Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes.  In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells.  Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268).  The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.  Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen.  The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
What are the official names of this protein?
Immunoglobulin lambda constant 7, Ig lambda-7 chain C region.
What are the subcellular locations of this protein?
Secreted. Cell membrane.
Protein: RS18_STRT1
Sequence: MAQQRRGGFKRRKKFDYIAANKIEYVDYKDTELLSRFVSERGKILPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: RL27_MYCBO
Sequence: MAHKKGASSSRNGRDSAAQRLGVKRYGGQVVKAGEILVRQRGTKFHPGVNVGRGGDDTLFAKTAGAVEFGIKRGRKTVSIVGSTTA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: IBPB_ECODH
Sequence: MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
What is the function of this protein?
Associates with aggregated proteins, together with IbpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress.  Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE.  Its activity is ATP-independent.
What are the official names of this protein?
Small heat shock protein IbpB, 16 kDa heat shock protein B.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PHNC1_RHOP5
Sequence: MLRIDNLDKRYKTGDLALKGVSLHIGAGDIVGLIGPSGAGKSTLIRCVNRLVPPTGGSIRLGDTELTRLGGADLRRARRRIGMIFQEFALIERLTVMENVLSGRLGYVGFWASWFRRFPQADVQRAFALLARVGLSDQVDKRADALSGGQRQRVGIARALAQDPELLLIDEPTASLDPKTSRQVMRLITELCAERRLAAIVNIHDVALAQMFLPRIVGLRAGEVVYDGPASGLTPDVLTSIYGEEDWSKTSDDVEIVDAAPRAADLSAPLKLDPALARL
What is the function of this protein?
Part of the ABC transporter complex PhnCDE involved in phosphonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Phosphonates import ATP-binding protein PhnC 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: ACTG_TRIVU
Sequence: MEEEIAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
What are the official names of this protein?
Actin, cytoplasmic 2, Gamma-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: DXS_PROMS
Sequence: MLLSELSHPNQLHGLTVSQLEEIACQIRERHLQVVSTSGGHLGPGLGVVELTLALYQTLDLDFDKVVWDVGHQGYPHKLITGRFSQFDSLRQQNGVAGYLKRSESKFDHFGAGHASTSISAALGMAIARDRKGENYKCVAVIGDGALTGGMALEAINHAGHLPNTPLVVVLNDNDMSISPPVGALSSYLNKVRVSPPLQFLSDSVQESVKNIPLIGKDIPEELKNIKGSVRRLSVPKVGAVFEELGFTYMGPIEGHDIANLIKTFNAAHKLKRPVLVHVVTTKGKGYPYAEADQVGYHAQSAFDLTTGKSIPSKKPKPVSYSKIFGQTLLKICEQDSKVIGITAAMATGTGLDILQKNIPDQYIDVGIAEQHAVTLAAGMSCDGLKPVVAIYSTFLQRAFDQLIHDVGIQNLPVSFVLDRAGIVGADGPTHQGQYDISYMRSIPNFVLMAPKDESELQRMLITSINHNGPTALRIPRGSGLGVAVMDEGWEPMNIGEAEILEEGEDILIIAYGSMVASAIETAKILKNMNINACIVNARFVKPLDKNLIMPLASRIQKVVTMEEGTLIGGFGSAIVELFNDNEINIPVYRIGIPDVLVDHASPDQSKEKLGLLPDQMADKIIKKFKLVI
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: YAJQ_ECOUT
Sequence: MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKNFRD
What are the official names of this protein?
UPF0234 protein YajQ.
What is the protein family that this protein belongs to?
Belongs to the UPF0234 family.
Protein: ZAPD_YERPP
Sequence: MSDLTSTILFEHPLNEKMRTWLRMEFLLQQLESHRSLDNIANALTFFRTASDLIDVLERGEVRTDLLKELERQQQKLQQWADIPGVDVSLVDSLRNQLKSRAAVLMSAPRIGQSLKEDRLISVVRQRLSIPGGCCSFDLPTLHVWLHQPSEQRDQHINKLLASLAPLHQSLTIILDLIRQSCPLRSQISLNGFFQDNAGGADLLRLRLPLDPQLYPQISGHKTRYAIRFLALDSENGTVPARLSFELACC
What is the function of this protein?
Cell division factor that enhances FtsZ-ring assembly.  Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
What are the official names of this protein?
Cell division protein ZapD, Z ring-associated protein D.
What is the protein family that this protein belongs to?
Belongs to the ZapD family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Localizes to mid-cell in an FtsZ-dependent manner.
Protein: MSRB_BRUSU
Sequence: MKYQKSAEAIAKLSAEQYRVTQENGTERPGTGEYLYNKEPGIYVDIVSGEPLFASSDKYESHCGWPSFTKPIERANVTELTDMSHGMVRTEVRSAHGDSHLGHVFPDGPVDRGGLRYCINSASLRFVPKDRMEAEGYGDYLDQVEG
What are the official names of this protein?
Peptide methionine sulfoxide reductase MsrB, Peptide-methionine (R)-S-oxide reductase.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
Protein: FMT_PELUB
Sequence: MTKKIVFMGTPFFAVPILKSLYEKNYIIPAVYTQPPKKSQRGQKINKSPIQIVAEDYNIDCRTPDTLKTNKEEYEYLKQLDLDLVIVVAYGQIIPKEYLNLAKKGFINIHASLLPKWRGAAPIQRSIMNLEKETGISIMKIGEKLDTGPVGNIYRIKIKDSDNAETISTKLSILASEKIIENVENIFEDKLTFKEQDDTSATYASKIEKSEGEIKWNDNAESIIGKINGLYPSPGAFFIFKDERYKILKAELGNKSGEIGEVMSNDLEISCGNQKSIKIIEIQRQGKKPQNINEFVLGSQIIKGSRITNV
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: XGPT_YERE8
Sequence: MSEKYVVTWDMLQIHARKLASRLLPADQWKGIIAVSRGGLVPAGILARELGIRYVDTVCIASYNHDNQGELKVLKRAEGDGEGFIVIDDLVDTGGTAKAIREMYPKAHFVTIFAKPAGRPLVDDYEVDIPQGTWIEQPWDMAVTFVAPLSAK
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: EBA3_ELIME
Sequence: MKKIFFAQCSILLLMLGSCSKMTEDMTPESVNKEASVKSATALAGSNGVCIAYYITDGRNPTFKLKDIPDKVDMVILFGLKYWSLQDTTKLPGGTGMMGSFKSYKDLDTQIRSLQSRGIKVLQNIDDDVSWQSSKPGGFASAAAYGDAIKSIVIDKWKLDGISLDIEHSGAKPNPIPTFPGYAATGYNGWYSGSMAATPAFLNVISELTKYFGTTAPNNKQLQIASGIDVYAWNKIMENFRNNFNYIQLQSYGANVSRTQLMMNYATGTNKIPASKMVFGAYAEGGTNQANDVEVAKWTPTQGAKGGMMIYTYNSNVSYANAVRDAVKN
What is the function of this protein?
Endohydrolysis of the di-N-acetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins.  Hydrolyzes bi- and triantennary glycans.  The presence of a core-bound fucose greatly augments endo F3 activity on biantennary and, presumably, triantennary oligosaccharides.
What are the official names of this protein?
Endo-beta-N-acetylglucosaminidase F3, Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase F3, Endoglycosidase F3, Mannosyl-glycoprotein endo-beta-N-acetyl-glucosaminidase F3.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 18 family.
What are the subcellular locations of this protein?
Secreted.
Protein: DAPF_PELUB
Sequence: MDIKAFKMDGLGNDFVIIDQRSQDFNLDKDQIIKICDRSFIGCDQLILIKKNKEIDANVEFFNSDGSISGACGNGTRCVADLLSKESGKKEITLLTTSGSLKSKILGNNLVETEIGIPKVNWQEIPLSKQLDTQDLKIEIIDRNNTKHIGGIAINVGNPHIIFFVDDIEAFDLKNIGPKIENHPLFPEKCNVTLAKVINRNLIKVKVWERGAGLTKACGTAACATAVAANINNLVEKTTDIEFVLGSLTISIDERNSIHMKGPVSDIKNINIKL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF4E_BOVIN
Sequence: MATVEPETTPTPNPPPTEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETVLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENREAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
What is the function of this protein?
Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.  In addition to its role in translation initiation, also acts as a regulator of translation and stability in the cytoplasm (By similarity).  Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression: in the complex, EIF4E mediates the binding to the mRNA cap.  Component of a multiprotein complex that sequesters and represses translation of proneurogenic factors during neurogenesis (By similarity).  In P-bodies, component of a complex that mediates the storage of translationally inactive mRNAs in the cytoplasm and prevents their degradation (By similarity).  May play an important role in spermatogenesis through translational regulation of stage-specific mRNAs during germ cell development (By similarity).
What are the official names of this protein?
Eukaryotic translation initiation factor 4E, eIF-4E, eIF4E, mRNA cap-binding protein.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic initiation factor 4E family.
What are the subcellular locations of this protein?
Cytoplasm, P-body. Cytoplasm. Cytoplasm, Stress granule. Nucleus. Note=Interaction with EIF4ENIF1/4E-T is required for localization to processing bodies (P-bodies). Imported in the nucleus via interaction with EIF4ENIF1/4E-T via a piggy-back mechanism.
Protein: METK_BRARP
Sequence: METFLFTSESVNEGHPDKLCDQISDAVLDACLEQDPDSKVACETCTKTNMVMVFGEITTKATVDYEKIVRDTCRSIGFISDDVGLDADKCKVLVNIEQQSPDIAQGVHGHFTKRPEDIGAGDQGHMFGYATDETPELMPLSHVLATKIGAKLTEVRKNGTCRWLRPDGKTQVTVEYYNDNGAMVPVRVHTVLISTQHDETVTNDEIARDLKEHVIKPIIPEKYLDDKTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSGKDPTKVDRSGAYIVRQAAKSVVANGMARRALVQVSYAIGVPEPLSVFVDTYGTGLIPDKEILKIVKESFDFRPGMMTINLDLKRGGNGRFLKTAAYGHFGRDDPDFTWEVVKPLKWDKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, Methionine adenosyltransferase, MAT.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LACG_STRZJ
Sequence: MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWYTAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAECHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNEIGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHALPTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDLREEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRRVAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDDGRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERYPKKSAHWYKKVAETQIID
What are the official names of this protein?
6-phospho-beta-galactosidase, Beta-D-phosphogalactoside galactohydrolase, PGALase, P-beta-Gal, PBG.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 1 family.
Protein: LGUL_RAT
Sequence: MAEPQPASSGLTDEAALSCCSDPDPSTKDFLLQQTMLRIKDPKKSLDFYTRVLGLTLLQKLDFPSMKFSLYFLAYEDKNDIPKDKTERTAWAFSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYEACKRFEELGVKFVKKPDDGKMKGLAFVQDPDGYWIEILNPNKMATII
What is the function of this protein?
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione (PubMed:8719777).  Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B (By similarity).  Required for normal osteoclastogenesis (By similarity).
What are the official names of this protein?
Lactoylglutathione lyase, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase.
What is the protein family that this protein belongs to?
Belongs to the glyoxalase I family.
Protein: Y1540_CLOP1
Sequence: MAIFRDQAENHVEHDRSIEDRRRHRQLVEKSIKENLGDILSEESIIGETKNKKYKIPIRGIKEYQFIYGANNKGVTTGTGEERRGDRISSDKRKAISNNKAGNQEGKDIYETEITLEELMDYIVEDLDLPNLDRKKYSEIIVESAAKKRGYQKYGVRPRLAKKKTVMCKIARKQGKKRALREIGEEAEIGRFPFREDDLRYYKVKKHPKKESNAVMIFIMDVSGSMDNTKKYLARSFFFVLSRFIRRKYNNVAFEFISHTTTAKNVNEYEFFHKGESGGTYISSGINAAIDLIKEKYNPGVWNIYPFYASDGDNWSEDNEKAMEAVNEISDLSNMFGYIELLPSTYSTTMFYRFKKEISKKNFVSVTVKEKKDLWNAIKYMLSEELQEKNKE
What are the official names of this protein?
UPF0229 protein CPF_1540.
What is the protein family that this protein belongs to?
Belongs to the UPF0229 family.
Protein: RSMH_PROM5
Sequence: MQTDLSNSSLFNHKSVMTDEILYSIDQYPFISDNKLTAIDATLGGGGHSYQLLKKYPDLKIIGLDHDPIARESALNKLEEFKSRIEIIPSNFSNFEPKEKVSFVIADLGVNSNQIDSPERGFSFQKDGPLDMRMNPLIKMNAENLIETLSEKDLADLIFKFGDERLSRKISRKIKKDLKEKGKYSGTKDLAYSIAGCFPPKQRYRKIHPATRTFQALRIAVNNEIEALEKFLKIAPDWLLTGGIISIISFHSIEDRLVKNSFKGDYRLKNLTKKPITPNKKEIENNKRSRSAKLRIAQLK
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MURA_PECCP
Sequence: MDKFRVQGPTRLAGEVTISGAKNAALPILFAALLAEEPVEIQNVPKLRDIDTTMKLLGQLGARVERNGSVHVDASNVNVFCAPYDLVKTMRASIWALGPLVARFGQGQVSLPGGCAIGARPVDLHIYGLEQLGAQIVLEEGYVKATVDGRLKGAHIVMDKVSVGATVTIMSAATLAEGTTIIENAAREPEIVDTANFLNTLGAKISGAGSDKITIEGVARLGGGVYRVVPDRIETGTFLVAAAVSRGQIICRNTRPDTLDAVLAKLREAGAEIEIGEDWISLDMHGKRPKAVTVRTSPHPGFPTDMQAQFSLLNLVAEGTGVITETIFENRFMHVPELIRMGAQAEIESNTVICHGVDKLSGAQVMATDLRASASLVLAGCIAEGVTIVDRIYHIDRGYDRIEDKLRALGANIERVKEHE
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Enoylpyruvate transferase, UDP-N-acetylglucosamine enolpyruvyl transferase, EPT.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HTPX_THEKO
Sequence: MGLVMWLRTGVLMAILTGLLMGIGYLFGGPNVAFIMFLFSMFFNFITYWYSDRIVLSWYNARIVDEYEAPELYAIVRDLAQRAGLPTPRVAIIPSETPNAFATGRDPKHAVVAVTQGLLRILNRDELEGVIGHELTHIKNRDILIGTVAAAMAGAIMQLAYWARWIAIFGGFNRDRDDGGDIIGAILVAILAPIAAMLIQAAISRSREFLADEGGARISGKPHALASALMKIEQAVNYRPMREGNPATAHMFIVNPFRGMSIANLFSTHPPTEARIERLRKIAEEMGIYF
What are the official names of this protein?
Protease HtpX homolog.
What is the protein family that this protein belongs to?
Belongs to the peptidase M48B family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LUXG_VIBHA
Sequence: MLCSIEKIEPLTSFIFRVLLKPDQPFEFRAGQYINVSLSFGSLPFSIASCPSNGAFLELHIGGSDISKKNTLVMEELTNSWGCGNMVEVSEARGKAWLRDESVKPLLLVAGGTGMSYTLSILKNSLAQGFNQPIYVYWGAKDMENLYVHDELVDIALENKNVSYVPVTEISTCPQYAKQGKVLECVMSDFRNLSEFDIYLCGPYKMVEVARDWFCDKRGAEPEQLYADAFAYL
What is the function of this protein?
Probable flavin reductase in the luminescent systems of different marine bacteria.
What are the official names of this protein?
Probable flavin reductase.
What is the protein family that this protein belongs to?
Belongs to the Fre/LuxG FAD/NAD(P) flavoprotein oxidoreductase family.
Protein: LIPA_RHIEC
Sequence: MVTILDTINPDAKRVRHPEKAHRPDTEVMRKPDWIRVKAPTSKGYAETRAIVKEHKLVTVCEEAGCPNIGECWDKKHATFMIMGEICTRACAFCNVATGKPNALDMDEPENVAKAVREMGLSHVVITSVDRDDLEDGGAEHFEKVIWAIRSASPATTIEILTPDFLKKPGALERVVAAKPDVFNHNMETVAGNYLTVRPGARYFHSIRLLQRVKELDPTMFTKSGIMVGLGEERNEVLQLMDDLRTADVDFLTIGQYLQPTRKHHKVESFVTPEEFKSYETVAYSKGFLMVASSPLTRSSHHAGDDFARLRAAREKKLLMAAE
What is the function of this protein?
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
What are the official names of this protein?
Lipoyl synthase, Lip-syn, LS, Lipoate synthase, Lipoic acid synthase, Sulfur insertion protein LipA.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. Lipoyl synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AHL10_ARATH
Sequence: MSGSETGLMAATRESMQFTMALHQQQQHSQAQPQQSQNRPLSFGGDDGTALYKQPMRSVSPPQQYQPNSAGENSVLNMNLPGGESGGMTGTGSEPVKKRRGRPRKYGPDSGEMSLGLNPGAPSFTVSQPSSGGDGGEKKRGRPPGSSSKRLKLQALGSTGIGFTPHVLTVLAGEDVSSKIMALTHNGPRAVCVLSANGAISNVTLRQSATSGGTVTYEGRFEILSLSGSFHLLENNGQRSRTGGLSVSLSSPDGNVLGGSVAGLLIAASPVQIVVGSFLPDGEKEPKQHVGQMGLSSPVLPRVAPTQVLMTPSSPQSRGTMSESSCGGGHGSPIHQSTGGPYNNTINMPWK
What is the function of this protein?
Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs).
What are the official names of this protein?
AT-hook motif nuclear-localized protein 10, AT-hook protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: SNP23_HUMAN
Sequence: MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNKCCGLCVCPCNRTKNFESGKAYKTTWGDGGENSPCNVVSKQPGPVTNGQLQQPTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLIDS
What is the function of this protein?
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.
What are the official names of this protein?
Synaptosomal-associated protein 23, SNAP-23, Vesicle-membrane fusion protein SNAP-23.
What is the protein family that this protein belongs to?
Belongs to the SNAP-25 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cell membrane; Lipid-anchor. Synapse, synaptosome. Note=Mainly localized to the plasma membrane.
Protein: ATPB_FUSBL
Sequence: MTMATTVSKGKVTQVIGAVVDVQFEGVLPAILNALETTNNGKKLILEVAQHLGENTVRCIAMDATEGLVRGAPVSDSGTPISVPVGNATLGRILNVVGEPIDERGPIAATEKRAIHQKAPDFQSQSTESQILVTGIKVIDLLAPYSKGGKIGLFGGAGVGKTVLIQELINNIAKVHSGYSVFAGVGERTREGNDLYHEFIESGVINIDDLEKSKVALVYGQMNEPPGARARVALTGLTLAEQFRDQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGQLQERITSTKAGSITSVQAIYVPADDLTDPAPATSFAHLDATTTLSRAISELGIYPAVDPLDSTSRLMDPQILGEEHYNTARAVQGILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAQVFTGSPGVQVPLDKTIASFKAVVAGEYDHLPEAAFYMVGDIEEAKAKAAKLAAAAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: VIRB8_BARHE
Sequence: MKHSLRTLWRLRVKINEFNEYIKEARSFDIDRMHGMRQRMRIAMALTVLFGLMTIALALAVAALTPLKTVEPFVIRVDNSTGIIETVSALKETPNDYDEAITRYFASKYVRAREGFQLSEAEHNFRLVSLLSSPEEQSRFAKWYAGNNPESPQNIYQNMIATVTIKSISFLSKDLIQVRYYKTVRELNDKENISHWVSILNFSYINAQISTQDRLINPLGFQVSEYRSDPEVIQ
What is the function of this protein?
The type IV secretion system VirB/VirD4 is a major virulence determinant for subversion of human endothelial cell (HEC) function.  VirB-dependent changes of HEC include massive cytoskeletal rearrangements, a pro-inflammatory activation by nuclear factor NF-kappa-B, inhibition of early and late events of apoptosis, leading to an increased cell survival, and, at high infection doses, a cytostatic or cytotoxic effect, which interfers with a potent VirB-independent mitogenic activity.  These changes of HEC require the T4S coupling protein VirD4 and at least one of the effector proteins BepA-G.
What are the official names of this protein?
Type IV secretion system protein virB8.
What is the protein family that this protein belongs to?
Belongs to the virB8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: RS17_METLZ
Sequence: MAKNIGLNVAVPEKDCDDVNCPFHGSLPVRGQVITGKVVSERMQGTVVVERNFLHKVQKYDRYEKRSSKIHAHMAPCLNAKIGDEVKIAECRPLNKTTSYVVVEVIKE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.