PharMolix/UniProtQA huggingface dataset:
Protein: RUVB_STRPG
Sequence: MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTRAGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: MTBC_ORYSI
Sequence: MACCGGGRGEGAAATESEAYLEGEAVREARELVAELCRHFYGQGWVTGTVGSITVKANDPALPLADQLIVMSPSGVQKERMVAEDMYVLSADGKVLSSPVSKPWPNKPPKCTDCAPLFMKAYLMRGAGAVIHSHGMETCIATMLDHGAKEFRMTHMEMIKGIKGHGYRDELVVPIIENTPYEYELTDSLAEAIAAYPKATAVLVRNHGIYVWGDSWINAKTQAECYHYLFDAAIKLYQLGIDWTTPEHGPINSAKRPRSVLSSSIPNGCPDSKSSKHCVVLDIEGTTTPISFVTDVMFPYARDNVRKHLTSTYSSDETKEDIKLLRIQVEEDLKNGIVGSVPIPPDDADKEEVINALVANVESMIKADRKITSLKQLQGHIWRTGFESKELQGVVFDDVPEALKHWHASGMKVYIYSSGSREAQRLLFGNTAYGDLRQYLCGFFDTTTGNKRETRSYFEISQSLGVDSPAQILFITDVFQEAVAAKSAGFEVIISIRPGNAPLPENHGFRTIKSFSEI
What are the official names of this protein?
Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: RL31_TRIEI
Sequence: MPKADIHPEWYPEAKVYCNGEVVMTVGSTQPEIHVDVWSGNHPYFTGTQKIIDTEGRVERFMRKYSKQEGSGSKSNKSKSTKSKKGKGKK
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: YR831_MIMIV
Sequence: MHSVYTKYTIILILLVIYQGLPTNTQVASRIFGVGSKSSGPLYRQLIDIYSYTYDNAVFIFEDLPIDVILTQVDYIDYVGLDRCISHEYEEIFNLVQFPLAGQAIVMTYNIPELANLDTRIVIDRQTLGKIWTGEISKWNHPDIIALNPTLNGTLPDKEIKLGYNDDGNVSISGIVQAALSSFYGNFATEFNNAGQLFANMSFANESRCVNIGPSSRERFDWVKNTTYSLTFVNYADVFNNTNPNISVMNMYNKAGNLVEPSLESVQFAMADFKDEYSNNNFALDVFDAPGNNSWPLSYVNYIVMSKRFFQLDCSRADVVLKFIAWVYTNTAASKALTQNQFYPLDNTLKKVSIDNIYIVKCNNVSVSEQQYLISFGGSTSIVPSWLTAFTSGSIVAKYYSTLSSNSIELLTTHGCDFAVTINGVDQKFYQEIEDLAVMPLAAFSIVPAYNIPEIVGKTLVLDIDVIVKIYLGEITNWNDTKIRNLNPEISNYLPNAIINVVVQNIESDINQIFTKFLSQESEIFSQEIGQTYNPDLSLFNSSVIFVDDIDGLGDELIDNKYSFGFWTDFGVRLLSRVQTVQMASLKINDDIIEPNYDTLKNAISSESNQIARSTNSNVWPITSMISIVYPETTMKNKDKAVAIAEFMYWTQYDPLAINSANNKGYYLASSDPQLRSVVLDLLKNFKFEDESVSSYANCIYQGSICSNFGTCIESACICNSSRTGTYCEKIITDSENNTLIIILATVIPIACIFGLLLLTLLIVIIFLLKHRNTTNNDWEIDFSELEIGETLGTGGYGEVYKSIWKGTEVAVKLISSKHVSKDMERSFFEEVKIMTSLRHPNVVLFMAASTKSPNMCIVMEFMSLGSLYDLLGNELIPEIPYALKIKMAYQASKGMHFLHSSGIVHRDLKSLNLLLDSKWNVKVSDFGLTKVKSELDKKKTNDNIIGTIHWIAPEILNDSTEVDYILADVYSFGIILWELLTREQPYKGMTPAAIAVSVIRDGMRPPISDEAVTAHSIEYIDLIKQCWHSDTIIRPTFLEIMTRLSNILGDSSNMTSGTSSSSLSSGGIGKSITDSKSSNSRSSVESSNTSNTFRGIDRHNSHPTGEVTVAFIDIISASKLWEYDPDGMCESTKMYNEIIRRVTKKYGGYESFISKDRNSGEGSFCLVFSDAIQAINSCEEMQLQLLNANWPKKILQHPAAAEEFDRTDQLIFRGLRVRMALHCGSVKISQDPMTRKYQYSGSTVNITGKITTLTHGGQIIVSENLYQKVNNDFTFITVGKIDIPDYPSKMTLYEIKFEILKNRFFGGITYVNYNDDTDSGTADDSNYDSGKIIDIDYMADIDKEDSFLTSANMCRWIINYDEISIGKQIGLGSYGIVFNGKWKGVDVAVKKFVKQKLSETQLLEFRAEMAFLSELKHSNIVTFIGACIKKPNICIVTEYMRMGNLRDVLKNPDIKITFANKLKLLYGAAMGIDYLHSSNPMIVHRDIKPANILVDEHFNVKIADFGFARIKEDNTTMTRCGTPCWTAPEVIRGEKYCEKADVFSFGVVMWEVLTGKEPFAECNFMKVSLDILEGGRPIIPSDCPHEFAKLIKKCWHAKAHKRPTMTEVVQQLMLITEQFDHKV
What are the official names of this protein?
Putative serine/threonine-protein kinase/receptor R831.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: 36014_ASFWA
Sequence: MLSLQTLAKKVVACNYLSSDYDYMLQRFGLWWDLGPIHLCNNCKQIFSYKHLQCFSEDDLCLEAALVKAVKSDNLELIRLFVDWGANPEYGLIRVPAVHLKRLCTELGGLTPVSEPRLLEILKEVAKLKSCAGVLLGYDMFCHNPLLETVTRTTLDTVTYTCSNIPLTGDTAHHLLTKFWFALALRHNFTKAIHYFYKRHKNHLYWRVACSLYFNNIFDIHELCREKEICISPNLMMKFACLRKKNYAAIYYCYRLGASLDYGMNLSIYNNNTLNMFFCIDLGATDFDRAQRIAHKTYMYNLSNIFLVKQLFSRDVTLALDVTEPQEIYDMLKSYTSKNLKRAEEYLTAHPEIIVID
What is the function of this protein?
Plays a role in virus cell tropism, and may be required for efficient virus replication in macrophages.  Inhibits also the host cGAS/STING-mediated type I interferon production by inducing host IRF3 degradation through the proteasome pathway.
What are the official names of this protein?
Protein MGF 360-14L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus MGF 360 family.
What are the subcellular locations of this protein?
Host cytoplasm.
Protein: PSK2_ARATH
Sequence: MANVSALLTIALLLCSTLMCTARPEPAISISITTAADPCNMEKKIEGKLDDMHMVDENCGADDEDCLMRRTLVAHTDYIYTQKKKHP
What is the function of this protein?
Promotes plant cell differentiation, organogenesis and somatic embryogenesis as well as cell proliferation.
What are the official names of this protein?
Phytosulfokines 2, AtPSK2.
What is the protein family that this protein belongs to?
Belongs to the phytosulfokine family.
What are the subcellular locations of this protein?
Secreted.
Protein: CTU2_VANPO
Sequence: MSDSHSHSDILLCQRCNKNHASVISRKEKFCTDCFRNFVSLKQRKQMMSDQYYQDIFKVMYKDKLRSEQDAHLQNLNSKILVPLSFGSSSLVMLDILNDTLLEQSITHRGKTGFTVDVIICFHDEQIQNQIKENVSKLINAKYKENNQKIKFHLVDINQFFDNSPHLQSLVLQETDFLIKSLNLKDQSIIEKKLTLSEILDQCSDRSTYQDLLAFVTKHAIKKYAFQHDFKAILWGHSMTRLADEVISLIVKGRGSAISSSLNTDDFDENYGNKFKNLYPLKDILLTEIDAYCYNSGLHNYLINYNIQDALLVNKINQNTDKIQTNSLKNKTINELARNYFEVIEGDYSNVISTVVRTGDKLAEPKSQENFKISKCNLCMQKIYSDPSQWITSITENKGHPLETDEEKENYQRWKNYNNDKLKNSEMDFFRLNEFVKENGSKACLCYGCTITLNTFKDKSVVWPVHDDKELNSVLEDYVLTDHEE
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln).  May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Cytoplasmic tRNA 2-thiolation protein 2.
What is the protein family that this protein belongs to?
Belongs to the CTU2/NCS2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMH_RHILW
Sequence: MTADTSLRPADHPAVKSGKVGVLLVNLGTPDGTDYTSMRRYLREFLTDRRVIEWSPWKWYPILFGVVLNTRPRKVGKAYELIWNKEKNESYLRTYTRNQSELMAEHLKDLATVKVDWAMRYGTPSIASRIEALKQEGCDRIVLFPLYPQYAAATTATVNDKAFQKLLSMRWQPALRTVPDYHDDETYIEALATSVEKHLATLDWKPEMLLASFHGIPMSYFKQGDPYYCQCQKTGRLLRERLGLTKENFMVTFQSRFGPEEWLQPYTDKTVEKLAQDGVKRIAVINPGFVSDCLETLEEIAEQAAHSFHENGGEKFAHIPCLNDGEDGMTVLEKVVRRELQGWI
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NRDR_BURVG
Sequence: MRCPFCRHEDTQVVDSRVSEDGAAIRRRRRCSACDKRFTTYERVELNLPAVVKKDGSRTEFDRRKIVASMQLALRKRPVAADAIDAAVARIEYQLLATGEREVRSEKLGELVMNELRGLDTIAYVRFASVYRRFEDVSEFADVIEEFRRASPSKPPRKR
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: PCP_VIBC1
Sequence: MKKVLMTGFEPFGGESINPALEAVKRLDGKKLDGGEVMICQVPVTRYESIDTVVNAIEQYQPDIVITVGQAAGRAAITPERVAINVDDFRIPDNGGHQPIDEPVILDGPDAYFTTLPIKAITSALHKASIPCQVSNTAGTFVCNHLFYGIQHYLRDKSVRHGFVHIPLLPEQDASGNQPTMSLDLIVEGLALLAQAVIDNESDVAITAGQIC
What is the function of this protein?
Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
What are the official names of this protein?
Pyrrolidone-carboxylate peptidase, 5-oxoprolyl-peptidase, Pyroglutamyl-peptidase I, PGP-I, Pyrase.
What is the protein family that this protein belongs to?
Belongs to the peptidase C15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AAEX_SHIF8
Sequence: MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFVWHPALFNTALYCCLFYLISRLFV
What are the official names of this protein?
Protein AaeX.
What is the protein family that this protein belongs to?
Belongs to the AaeX family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: OBG_BORRA
Sequence: MHLFKDSLNLIVSSGNGGAGCVSFLREKFKAKGGPDGGDGGRGGDVIFKVKSNLKTLSLYRNGQKLSASNGKSGMGLKKSGAAGSDLIIFVPPNTSIYDADSNCMLFELKNFNDEVVVLKGGRGGLGNVNFKSSTKRTPRFAQPGESGLTLNLRLELSLIADVGLVGLPNAGKSSLISKITASRSKVANYPFTTKIPHFGVVRVSYNDLIIADLPGIIEGASKGIGLGFEFLRHISKTQILVFLIDVSSNDFMSAYDILINELRVYDIGLLKKKRIIVASKLDLEGATENFNQLKSILSEERVLGISIYDNIGINELVSEFFSLAKI
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: U73E1_STERE
Sequence: MSPKMVAPPTNLHFVLFPLMAQGHLVPMVDIARILAQRGATVTIITTPYHANRVRPVISRAIATNLKIQLLELQLRSTEAGLPEGCESFDQLPSFEYWKNISTAIDLLQQPAEDLLRELSPPPDCIISDFLFPWTTDVARRLNIPRLVFNGPGCFYLLCIHVAITSNILGENEPVSSNTERVVLPGLPDRIEVTKLQIVGSSRPANVDEMGSWLRAVEAEKASFGIVVNTFEELEPEYVEEYKTVKDKKMWCIGPVSLCNKTGPDLAERGNKAAITEHNCLKWLDERKLGSVLYVCLGSLARISAAQAIELGLGLESINRPFIWCVRNETDELKTWFLDGFEERVRDRGLIVHGWAPQVLILSHPTIGGFLTHCGWNSTIESITAGVPMITWPFFADQFLNEAFIVEVLKIGVRIGVERACLFGEEDKVGVLVKKEDVKKAVECLMDEDEDGDQRRKRVIELAKMAKIAMAEGGSSYENVSSLIRDVTETVRAPH
What is the function of this protein?
May glycosylate diterpenes or flavonols in leaves.
What are the official names of this protein?
UDP-glycosyltransferase 73E1.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
Protein: Y912_HAEIN
Sequence: MNNKISVYDKDNFFELYQKLRANPISLNEIIEKPTMLSLLPNLKGKKLLDLGCGTGGHLQLYLERGAAKVIGTDLSEKMLEQAEKDLQKCGQFSGRFSLYHLPIEKLAELPESHFDVITSSFAFHYIENFPTLLSTIHDKLSSNGTLIFSQEHPITTCHKEGERWEKNDKKQQVAYRLNHYREEGKRNRNWFKQPFQTYHRTTATIINNLIHARFQIEQMEEPMLADQPQWHNEFKDLSHRPPLLFIKARKVEK
What are the official names of this protein?
Uncharacterized protein HI_0912.
Protein: HTPG_RICPR
Sequence: MTQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSNSELIAGDSNFKIIVKVDKDNGQIIIRDNGIGMNKEDLIENLGTIARSGTANFLKNLSGDSKKDNMLIGQFGVGFYSSFMVADKVTVTSRKAGESKVHTWESDGLGEYIVADSEQEFTRGTEIVLYIKKSETTFLDHFRLKHIVKSYSDHIAVPIYFCDEAGNNEIQLNSASALWTRPKSEITEDQYKEFYKSLSYAVDDPWVTLHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKKRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSEDLPLNISRESLQHNNVLEKIKNAITKRVLGELRKKKEELPEEYNKFWTNFGGALKEGLCEATTDHEKLLEVCIFRSALHNKMISIDEYIANFKEGQNTIYYLSGDNPDKLLSSPQIEGLLNKNIDVLLFTDTVDDFWVNVNSEYKGYAIKSATRSDIDVEQTTSQPKDKNTDSKKSDNEYKLLTDYFKEILGELVKEVKISKKLTLSPACLAVSDTAMDIRMERFLIEQKQIANASAKNLELNPKNKIIEKIFNDLKANNKNNNELVNLIFDQACILEGEPVADTGAFSKRLNDILQKAIL
What is the function of this protein?
Molecular chaperone.  Has ATPase activity.
What are the official names of this protein?
Chaperone protein HtpG, Heat shock protein HtpG, High temperature protein G.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y3475_ARATH
Sequence: MRLFLLLAFNALMLLETHGFTDETDRQALLQFKSQVSEDKRVVLSSWNHSFPLCNWKGVTCGRKNKRVTHLELGRLQLGGVISPSIGNLSFLVSLDLYENFFGGTIPQEVGQLSRLEYLDMGINYLRGPIPLGLYNCSRLLNLRLDSNRLGGSVPSELGSLTNLVQLNLYGNNMRGKLPTSLGNLTLLEQLALSHNNLEGEIPSDVAQLTQIWSLQLVANNFSGVFPPALYNLSSLKLLGIGYNHFSGRLRPDLGILLPNLLSFNMGGNYFTGSIPTTLSNISTLERLGMNENNLTGSIPTFGNVPNLKLLFLHTNSLGSDSSRDLEFLTSLTNCTQLETLGIGRNRLGGDLPISIANLSAKLVTLDLGGTLISGSIPYDIGNLINLQKLILDQNMLSGPLPTSLGKLLNLRYLSLFSNRLSGGIPAFIGNMTMLETLDLSNNGFEGIVPTSLGNCSHLLELWIGDNKLNGTIPLEIMKIQQLLRLDMSGNSLIGSLPQDIGALQNLGTLSLGDNKLSGKLPQTLGNCLTMESLFLEGNLFYGDIPDLKGLVGVKEVDLSNNDLSGSIPEYFASFSKLEYLNLSFNNLEGKVPVKGIFENATTVSIVGNNDLCGGIMGFQLKPCLSQAPSVVKKHSSRLKKVVIGVSVGITLLLLLFMASVTLIWLRKRKKNKETNNPTPSTLEVLHEKISYGDLRNATNGFSSSNMVGSGSFGTVYKALLLTEKKVVAVKVLNMQRRGAMKSFMAECESLKDIRHRNLVKLLTACSSIDFQGNEFRALIYEFMPNGSLDMWLHPEEVEEIHRPSRTLTLLERLNIAIDVASVLDYLHVHCHEPIAHCDLKPSNVLLDDDLTAHVSDFGLARLLLKFDEESFFNQLSSAGVRGTIGYAAPEYGVGGQPSINGDVYSFGILLLEMFTGKRPTNELFGGNFTLNSYTKSALPERILDIVDESILHIGLRVGFPVVECLTMVFEVGLRCCEESPMNRLATSIVVKELISIRERFFKASRTTWR
What are the official names of this protein?
Probable LRR receptor-like serine/threonine-protein kinase At3g47570.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: DCLK1_MOUSE
Sequence: MSFGRDMELEHFDERDKAQRYSRGSRVNGLPSPTHSAHCSFYRTRTLQTLSSEKKAKKVRFYRNGDRYFKGIVYAISPDRFRSFEALLADLTRTLSDNVNLPQGVRTIYTIDGLKKISSLDQLVEGESYVCGSIEPFKKLEYTKNVNPNWSVNVKTTSASRAVSSLATAKGGPSEVRENKDFIRPKLVTIIRSGVKPRKAVRILLNKKTAHSFEQVLTDITDAIKLDSGVVKRLYTLDGKQVMCLQDFFGDDDIFIACGPEKFRYQDDFLLDESECRVVKSTSYTKIASASRRGTTKSPGPSRRSKSPASTSSVNGTPGSQLSTPRSGKSPSPSPTSPGSLRKQRISQHGGSSTSLSSTKVCSSMDENDGPGEGDELGRRHSLQRGWRREESEEGFQIPATITERYKVGRTIGDGNFAVVKECIERSTAREYALKIIKKSKCRGKEHMIQNEVSILRRVKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTSKYTERDASGMLYNLASAIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATIVDGPLYTVCGTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYWDNVSDSAKELINMMLLVNVDQRFSAVQVLEHPWVNDDGLPENEHQLSVAGKIKKHFNTGPKPSSTAAGVSVIATTALDKERQVFRRRRNQDVRSRYKAQPAPPELNSESEDYSPSSSETVRSPNSPF
What is the function of this protein?
Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain.  May also participate in functions of the mature nervous system (By similarity).
What are the official names of this protein?
Serine/threonine-protein kinase DCLK1, Doublecortin-like and CAM kinase-like 1, Doublecortin-like kinase 1.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Protein: NDOR1_ASHGO
Sequence: MAATRIAILYGSETGTAQDFANILSHQLRRFHYKHTVCSIGEYSAQNILACQYLFVICSTTGQGALPQNARQSPQGKVEGTLWSVLKRSSLPPTLLDHLQVAFLGLGDSSYSKFNFAIRKLHNRIVGQLGAREIFPRLEADAIGLAGSNAGNGNGIELVYSEFEKRVLSFLNDQFPFMTVNGEQVPREPIATDIYLKPEYYLEASGNDKGTASVPCTFEGDSSVKYGTVVTNKRITATDHFQDVRQLVFSSQDGENYYPGDTVSIYPYNTDADVQAFIDTQQHWASIADVPLQIKTPTSARGICDGGLVSPLTLRNLLKYHCDIVSIPMRSFFMKTWTFAVDHERLPDGKDQLQQQRDKLREFAESEDMQDIYDYCNRPRRSILEVVQDFMSLRLPWEYILDYLPHIKPRFFSISSQPCNKDIELTIAIVRYKTILRRIRRGLCTNYISDLSEGSIIRYKVQYNDLLPAGKQDRPVIMISPGVGLAPMKCLIYAQLFNPMLLFFGNRYKDKDFLYADTLQKWADENRIKLFVCFSRSPDDSPGLKYVQDAVWENAREVARLITEENAVVYVCGSSGKMPVQVRLTLCEVLKKWGNFPDDKASEEYLKDMENSDRYLQETW
What is the function of this protein?
NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.  Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery.  In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins.  Positively controls H(2)O(2)-induced cell death.
What are the official names of this protein?
NADPH-dependent diflavin oxidoreductase 1, NADPH-dependent FMN and FAD-containing oxidoreductase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Note=Relocalizes to mitochondria after H(2)O(2) exposure.
Protein: TRFR_HUMAN
Sequence: MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANYSVALNYSVIKESDHFSTELDDITVTDTYLSATKVSFDDTCLASEVSFSQS
What is the function of this protein?
Receptor for thyrotropin-releasing hormone (TRH).  Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
What are the official names of this protein?
Thyrotropin-releasing hormone receptor, TRH-R, Thyroliberin receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PGK_TREPS
Sequence: MMLRTCKDVTMRGERVVVRVDFNVPMRDGMVQDDTRVTAAVPTLRYIIEQGPRHVVLISHLGDPTRDADKAEGNAKKDGCPFDRHAFINGKHRLKPVADCLAKKLGVPVHFAPSCVGQREFIEGLPDGSVVLLENVRFHPEETSGDAKVQEQFARELAQYGDIFVNDAFGTAHREHASTVVLPRLMRRRVAGLLIEREVRYLEPMVCNPKVPMVAVVGGAKVSSKIAVLESLLRTSTALIIGGGMAYTFLKAQGVGVGTSLVEDDFIDTARMLLQKAQSGGVSVVLPVDHVCASTFCADAQPVAVDDVHIPMHLMGMDVGPRTLEQYRAHLKGVSSVLWNGPVGVFEFDAFAHGTRVLAQLIAEATDAGATSVVGGGDSIAAVSKFGLASRMSHVSTGGGASLKLFEGKVLPGISCLET
What are the official names of this protein?
Phosphoglycerate kinase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLCD2_DANRE
Sequence: MELNSVILTTGSSVGFFKLVNYGLGKLPIPETARRNAWKWNNISTSFVHSLITGVWSVLCFCMHPQMAEDLIETHSVFSHALVSVSIGYFIYDFLDMVINQKIIHSWELLFHHVVVITCFGISVLTCRYVGFAVVALLVEINSVFLHLRQVLRMANLAKSTFYRVNSMINLGTYVVFRINTLAWMTRWLVLNRDLIPLFSYTIGSVGLAIMTAMNIVLFYRLMRSDFMKASREKELRKEKEKEKDM
What is the function of this protein?
Regulates the composition and fluidity of the plasma membrane (By similarity).  Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity (By similarity).  Does not appear to have any effect on LCPUFA synthesis (By similarity).
What are the official names of this protein?
TLC domain-containing protein 2.
What is the protein family that this protein belongs to?
Belongs to the TLCD family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYGB_BRASB
Sequence: MPDLLLELFSEEIPARMQAKAAEDLRRMVTDKLVAEGLVYEGAKAFATPRRLALTVHGIPARQADLKEERKGPRVGGPDAAIQGFLKATGLSSLEEATIQRDPKKGDFYVALIEKPGRATLDVLAEMLPVIVRTFPWPKSMRWGKRSEKPGALNWVRPLHAITATFGLETEEPDVVSFSVDGIEAGQTTYGHRFMAPAAISVRRFEDYEAKLLDAKVVLDPQRRKDTIVTDAKQLAFAQGYELVEDPVLLDEVSGLVEWPVVLMGSFDPEYLKVPAEVIRATIRNNQKCFVVRDPKTGGLAPKFILTANIEATDGGKTIIAGNERVIRARLSDAKFFYETDLKTRLEDRLPKFEQIVFHEKLGTQAARIARIEKLAAEIAPLVGADAAKTARAAKLAKADLLTEVVGEFPEVQGLMGKYYALAQGEDVSVAAACEEHYKPQGPGDRVPTDPVSVAVALADKLDTLVGFWAIDEKPTGSKDPYALRRAALGVIRLITENSLRLSLLQVAGSALAGLHVKSELDAGKLSADLLSFFADRLKVQLREQGARHDLVDAVFALGGQDDLLMVVRRVEALGKFLETDDGKNLLAGTKRASNILAIEEKKDKRKFDGAPDAALYRLDEEKALAKAIGEVGSEAGTAVAKEDFAAAMHAMAKLRPAVDAFFDKVKVNDDDAAIRENRLKLLNEIRNATRAVADFSKIEG
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSF1_CRYNB
Sequence: MYGDLALQLVNSSHRTTLSSTPQLPLPKYALPLILSICLETRQLGTSIASIAESHGQLSLTQDRGLVCNLTVQHLAARRNKRCMLAYLATRVGGIKERWWDAGGGLAYLLSPAASASVNPEADAPDLRSALSPQELDFLRGYNNLLLDYKSDFLDVLDLTAGIEKPPGEIMVDVRVVRDAGEVFLDSGERVDFRKGQRFRLERAQVERLIIQGYLEEV
What is the function of this protein?
The GINS complex plays an essential role in the initiation of DNA replication.
What are the official names of this protein?
DNA replication complex GINS protein PSF1.
What is the protein family that this protein belongs to?
Belongs to the GINS1/PSF1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MSS51_HUMAN
Sequence: MAPRSRRRRHKKPPSSVAPIIMAPTTIVTPVPLTPSKPGPSIDTLGFFSLDDNVPGLSQLILQKLNMKSYEEYKLVVDGGTPVSGFGFRCPQEMFQRMEDTFRFCAHCRALPSGLSDSKVLRHCKRCRNVYYCGPECQKSDWPAHRRVCQELRLVAVDRLMEWLLVTGDFVLPSGPWPWPPEAVQDWDSWFSMKGLHLDATLDAVLVSHAVTTLWASVGRPRPDPDVLQGSLKRLLTDVLSRPLTLGLGLRALGIDVRRTGGSTVHVVGASHVETFLTRPGDYDELGYMFPGHLGLRVVMVGVDVATGFSQSTSTSPLEPGTIQLSAHRGLYHDFWEEQVETGQTHHPDLVAAFHPGFHSSPDLMEAWLPTLLLLRDYKIPTLITVYSHQELVSSLQILVELDTHITAFGSNPFMSLKPEQVYSSPNKQPVYCSAYYIMFLGSSCQLDNRQLEEKVDGGI
What are the official names of this protein?
Putative protein MSS51 homolog, mitochondrial, Zinc finger MYND domain-containing protein 17.
Protein: RL24_CORJK
Sequence: MKIRKGDTVLVISGPDKGAKGKVIEAYPQRDKVLVEGVNRIKKHVANSAPERGAESGGIVTQEAPIHVSNVMVVDSDGNPTRIGYRFDEDGKKIRVSKRNGKDI
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MDTD_SALTY
Sequence: MTELPDNTRWQLWIVAFGFFMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFFAAIVLFTLGSLFCALSGTLNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTFVTLPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAMATFMLMPNYIIETRRFDLPGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLYLFHAKKNSGALFSLRLFRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQIVNRFGYRRVLVATTLGLALVSLLFMSVALLGWYYLLPLVLLLQGMVNSARFSSMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLLGMFGQQHIGIDSSATHHVFMYTWLCMAVIIALPAIIFARVPNDTQQNMVISRRKRSL
What are the official names of this protein?
Putative multidrug resistance protein MdtD.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. TCR/Tet family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SPEA_PROM0
Sequence: MTNFEPKKLKNVWTIEDSISTYNIDKWGDKYFSINSKGNISVTKDIKSENKIDLFKLVKELKSREINPPLIIRFNDILKDRINALHDSFFKAIKTYKYKNIYQGVFPVKCNQQKNVLEKIIDFGSQWNFGLEVGSKSELLIGLALLENHNSLLICNGYKDKKYIEIATLARKLGKNPIIVIEQRDEVKRIIQAVQELNATPLIGIRAKLSSKSSGRWGKSIGDNSKFGLSIPEIMLTIKELKEANLINEMKLLHFHIGSQISDIAVIKDALQEASQIYVELCKLGAPMQYIDVGGGLGIDFDGTKTSSNTSTNYSLQNYANDVIATIKDSCELNNIKHPTIISESGRAIISHCSVLIFNVLGTSHVSSKLQIFDKKNQQLIISNLLETYYELKKLKNKKINLSQIIELWNDAKKFKEDCLVAFRLGFLSLAERAYAEELAWACAKEISNNLNNDEINHPDLSEITETLASTYYANLSIFKSIPDSWAINQIFPIVPIHRHLEEPFCKGNFADLTCDSDGKLNNFIDDGKIKSLLNLHEPEKDKDYLIGIFMTGAYQEALGNLHNLFGSTNVVHIDINQDDSYKVKNIIKEDSKSEILQLLDYSSASLVESIRINTESAIDQKKLTIEEARKLMDQIEISLRKSSYLSE
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.