PharMolix/UniProtQA huggingface dataset:
Protein: SECA_METSB
Sequence: MLGSFAKKIFGSANERRLKSYRPKVAAINALEPEWLKLSNEELAAKTVAFREELAQGKSLDDLLVPAFATVREAARRVLGQRHFDVQLIGGMVLHEGAIAEMRTGEGKTLVATLATYLNALAGKGVHVITVNDYLARRDAEWMGRVYQFLGLTTGIIVHGVDDGERARSYAADITYGTNNEFGFDYLRDNMKYELSQMVQRGHSFAIVDEVDSILIDEARTPLIISGPSDDKSELYNTIDKVMPRLQPEDFEVDEKQRSTNLTERGNEHIEDLLRAAGVEIEGSLYEAANVTIVHHVNQALRAHKLFQRDKDYIVRNGEVVIIDEFTGRMMPGRRYSEGLHQALEAKEHVQVQPENVTLASITFQNYFRLYSKLAGMTGTASTEADEFAEIYKLDVVDIPTNLPVCRLDEDDEVYRSAEEKLRAIVREIEAANAKMQPMLVGTTSIEKSEQLAEAMKSHGYKQIDFAEPRALDKLYAAARAEKPSKLFAVLNARFHEQEAYIVAEAGVPGAITIATNMAGRGTDIKLGGNVDMRVAQECADLEPGEARDAKDAQIRAEVDDFKAKAIAAGGLYIIGTERHESRRIDNQLRGRAGRQGDPGRSKFFLSLKDDLMRIFGSDRMESMLVKLGLKEDEAIVHSWINKALEKAQQKVEARNFDMRKNILKYDNVMNDQRKVVFEQRREMMAKPSLEEMIDDMRQGVVDDLIARHIPRDAYPEAWDSEGLREGVKTSLNIDLPIVEWAKEEGITEDDMRERLQKAADEAYAARVERNGVDVTRYVEKQIVLQALDHLWREHLLTLDHLRQVVGWRGMAQRDPLNEYKSEAFQLFDELIAQLREATTAQLSRVEVAFEPPPGENGFSGGMQEISGPQGGSSGGPIFQEALSAAAFAPPPLAPLEFSDESGSTATLARPAQSASRDEPAGGYAKVGRNQPCPCGSGKKYKHCHGALT
What is the function of this protein?
Part of the Sec protein translocase complex.  Interacts with the SecYEG preprotein conducting channel.  Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
What are the official names of this protein?
Protein translocase subunit SecA.
What is the protein family that this protein belongs to?
Belongs to the SecA family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50- 50.
Protein: RLMM_PASMU
Sequence: MNKLALYCRPGFEKELAAEISEKAAELGIFGFARVEENQGYVIFECYQTDDADRLAREIPFNQLIFARQMIVVSDLLTDLPVQDRISPIIQQYQAIAHQINLTYSTELLVETADTNEAKSLSAFCRKFTVPLRQALKKQGWLQGTRHHKQGLTLHILMLDSTQCYVGYSYNYNHSEHFMGIPRLKFPLDAPSRSTLKLEEAILTFLSREEEKKRLNEQMYAVDLGACPGGWTYQLVKRGLFVYAVDHGKMAASLHDTGRIEHCAEDGFKFQPPKRSKIDWLVCDMVEQPSRISQLILKWLVNGWCHETIFNLKLPMKKRYLEVKKCLQMIEESLEKQGFRYHIQAKHLYHDREEITVHIAVKSLD
What is the function of this protein?
Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
What are the official names of this protein?
Ribosomal RNA large subunit methyltransferase M, 23S rRNA (cytidine2498-2'-O)-methyltransferase, 23S rRNA 2'-O-ribose methyltransferase RlmM.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLPS_MYCTO
Sequence: MAVVSAPAKPGTTWQRESAPVDVTDRAWVTIVWDDPVNLMSYVTYVFQKLFGYSEPHATKLMLQVHNEGKAVVSAGSRESMEVDVSKLHAAGLWATMQQDR
What is the function of this protein?
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
What are the official names of this protein?
ATP-dependent Clp protease adapter protein ClpS.
What is the protein family that this protein belongs to?
Belongs to the ClpS family.
Protein: RPOC_XYLFA
Sequence: MKDLLNLFNQQRQTLDFDAIKIGLASPALIRSWSFGEVKKPETINYRTFKPERDGLFCAAIFGPIKDYECLCGKYKRMKHRGVVCEKCGTEVTLAKVRRERMGSIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFEAYVVTEPGLTPLERRQLLTEEQYLQARQEHADDFDATMGAEAVYELLRMIDLQSEMARLREEIVVTGSETKLKRLTKRIKLIEAFIESGNRPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLCRLLELSAPDIIVRNEKRMLQESVDALLDNGRRGRAITGTNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSARSVIIVGPNLRLHQCGLPKKMALELFKPFVFAKLQRRGLATTIKAAKKLVEREEAEVWDILEEVISEHPVVLNRAPTLHRQGIQAFEPVLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMSRALENKKGEGMVFANTSELKRAYDNSVVELHAKVKVRITEIETDDRGLRSKASLIVDTTVGRALLSEILPEGLPFVLVNTEMTKKNISRLINSSYRMLGLKDTVVFADKLMYTGYAYATRAGVSICIDDMLIPIEKKEILGEAEQEVLEIQEQYQSGLVTAGERYNKVVDIWSRTNERIAKAMMDTIGTEKVVNTDGEIVDQKSMNSLYIMADSGARGSPQQIRQLAAMRGLMVRPDGSIIETPIKANFREGLSVQEYFNSTHGARKGLADTALKTANSGYLTRRLVDVTQDLCVVQLDCGTAGGLTMTPIVEGGDVVEPLKDRVLGRVVAEDVFLPGNDDEPIVTRSTLLDEQWVAKLEEAGVQSVKVRSPITCESPFGVCALCYGRDLARGHLVNMGEAVGVIAAQSIGEPGTQLTMRTFHIGGTALSAAAVDNITVKTSGSVKFTNLKYVEHVNGTLVAVSRSGEISVLDTHGRERERYKLPYGATINVKDMAEVKSGQILANWDPHNHPIVSEVAGFVRFIDFVDGVTVIEKTDDLTGLSSREIADLKRRGSQGKDLRPLVRIVDKKGNDLTIPGTDLSAQYLLPPRSIVNLQDGAPVGIGDVVAKIPQEASKTRDITGGLPRVADLFEARRPKDPAILAERSGVISFGKDTKGKQRLIIKDADGSEHEELIPKYRQIIVFEGEHVTKGETIVDGEPSPQDILRLLGIEPLAAYLVKEIQDVYRLQGVKINDKHIEVITRQMLRKVEIVDQGNSKFLNGEQVERQRVIDENAKLIARNELPAKYNPVLLGITKASLATESFISAASFQETTRVLTEAAVRGTRDNLRGLKENVIVGRLIPAGTGQRYHSQRRYSSVGLTQSEMETLVGRSTSSGTEVTSPSKDAIPLGG
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: SYR_DESAH
Sequence: MKESIKQLILGGARRAFDKGLLKSDEFPGMEIEAPRHEAHGDFSTNFAMVSAATQKMAPRKIAEAVISCMDSDSVIEKTEIAGPGFINFFLANRAWYPTLDRIVKEDDRFGSSDFGAGKKVQVEFVSANPTGPLHVGHARGAAVGDAVANILSFAGFDVQREYYINDSGRQIRTLGLSVWLRLCQQLGREVEFPTDCYQGDYIKEIAADLHGKMGRELSEKDEAEAVSICAKFAAQVILSGIRADLVAFGVEYDQWFSEESLYASGRVQKAIEEFKARDVIYEKDGAQWFRTERYGDEKDRVVVRNNGITTYFASDIAYHMEKFDRGFDRVIDVWGADHHGYINRINAAIDASGRQSDQFDVILVQLVNLLRNGQPVAMSSRSGEFVTLKDIVDEVGKDAARFLFLSRSYDSGLDFDLEVAKQKTSDNPVYYVQYVHARIAGILMKAVSEKVLNEAEKPGAGNRELLVEPEEINLLKILAAFPETVEKSAATLHPHVIFTYLMGLASAFHGYYNRHKVITPDRELSRGRISLVFAVKTVIRNGLNLLGVSAPERM
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIG_ANASK
Sequence: MADTWSIGAHAFTSRLLVGTGKYPDFPTMQRALAASGAEVVTVAVRRLDLSKKGEESLLAWIPKGMKLLPNTAACFTAEEAIRTARLGRELEMGDLVKLEVIGDRRTLFPDVEGLIQAAKVLVKEGFTVLPYTNDDPVTAKKLEDAGCAAVMPLGAPIGSGLGLRNPYNLRIIMETVQVPVLVDAGVGTASDAALAMELGAVAVLMNTAIAEAKDPVLMAEAMRAGVEGGRKAFLAGRIPMKLHAAASSPMSGLIGS
What is the function of this protein?
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine.  Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS.  In vitro, sulfur can be provided by H(2)S.
What are the official names of this protein?
Thiazole synthase.
What is the protein family that this protein belongs to?
Belongs to the ThiG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL34_HAMD5
Sequence: MKRTFQPSVLKRNRSHGFRARMANKNGRQVLARRRAKGRTRLTVSH
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: MIAA_PSEA8
Sequence: MSSLPPAIFLMGPTAAGKTDLAMALADALPCELISVDSALIYRGMDIGTAKPSRELLARYPHRLIDIRDPAESYSAAEFRADALAAMAKATARGRIPLLVGGTMLYYKALLEGLADMPGADPEVRAAIEAEAQAEGWEALHRQLAEVDPESAARIHPNDPQRLMRALEVYRLGGVSMSDLRRRQSAEKADFDASGRNQLPYTVAQLAIAPEQRQVLHARIAQRFRQMLEQGFIAEVEALHARSDLHAGLPSIRAVGYRQVWDYLDGKLSYAEMTERGIIATRQLAKRQFTWLRSWSHLHWMDSLAGDNLPRALKYLKTVSILA
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.
Protein: UL13_GAHVM
Sequence: MDTESKNKKTTNGGENSNCSHSTRTPDKSIEERFYNWERRSRTTNRFGTTVNSRSYNMYFQGTHNTSRRHTYGNIHHRRRFSDNIRRCLRQLCMKRKTPAKKRSDKLVSRPSLPEHVFTLARIKNVTTFIFNVTSELHYSHIDLKEMPIYAGSGSYGVVKIFKKTDIAVKKVLECFKTELLMTLIAGECALRAKSTLRINNIIPLLAFSIPSKELVFPAYHMDMDSYYHRLARIDKTVQHWKAIEKTFMDLGKAVVFLNVSCGLTHLDIKCGNIFVNVTEGPNPILVDAVIGDFSLALLNTNSTILKSRFDVNISSDKIQSLKVCRGNIKPVFDLVLGHGQTQPCELMIKALNGVGFERRSTPLTSDEGVSIDMYALGQSLMEVILAAGMNFTHRFGISSNPLHFYYHRLMRADYLLDILAYRCMLYQHLFPMTPLTSKNGIPWERAEKIRLQLHSSRHRAEFDKYLEAYDITHRKLFDSLNIFPYLNNLLELAALYCHANPVARTADLLLWN
What is the function of this protein?
Multifunctional serine/threonine kinase that plays a role in several processes including egress of virus particles from the nucleus, modulation of the actin cytoskeleton and regulation of viral and cellular gene expression.
What are the official names of this protein?
Serine/threonine-protein kinase UL13 homolog.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
What are the subcellular locations of this protein?
Virion tegument. Host nucleus.
Protein: GPMB_ECO8A
Sequence: MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
What are the official names of this protein?
Probable phosphoglycerate mutase GpmB, PGAM, Phosphoglyceromutase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. GpmB subfamily.
Protein: DAPA_XYLFA
Sequence: MSLSGIITALVTPFDRDGAFDRDAWIRLLDLQLAGGVQGVVIAGSTGEAATLTDAEYDEMLCSAVVRVGGRVPVLAGTGLSGTAKTISQTKRAADNGAGYALVVTPPYIRPNQGGLKAHYLAVADQGGLPVVLYNVPSRTGCDLLPETVADLAGHPNIVGIKEACASRERVQALLALRRPGFTVFSGDDSSAARSMLDGADGLVSVASNVLPSAYRHLCDLARAGERGAIDLWNARLSDFHAFCGLDSNPIPIKALLQRIGIGYGLRLPLLPLSVCHHDIADHLADQVAALEALSSRKIVAA
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HISX_METTH
Sequence: MLMKITEFDYRRISELVERARLDVDDVLGPVADIISMVRDGGDDALRELTGRFDGVTVENFRVSREEIEEAHKNLEPGVKEALREAASNIEEFHRMQMPSGWMSEVRPGVMAGQLVRPIDSVGCYIPGGRAVYPSTILMTVIPARIAGVERIVCCTPPAQDGSVPDAVLVAADMAGASEIYRVGGAQAVAAMAYGTETIRPVDKIVGPGNIFVTAAKKLVYGEVDIDFPAGPSEVLIIADETASPEYIALEILAQAEHDPQAASVLVTDSRDLALEVKEMVHENIKYMERANIIRESLERYGMIVLTADIDEAVDFSNAYAPEHLVIMTDSPEETLEGIRNAGSIFLGELSPVAAGDYGSGTNHVLPTSGCARMYSGLSTESFIKKPTVQRITKEGLRNLQGTVLKLAEYEGLHAHAESFRRRLRD
What is the function of this protein?
Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.
What are the official names of this protein?
Histidinol dehydrogenase, HDH.
What is the protein family that this protein belongs to?
Belongs to the histidinol dehydrogenase family.
Protein: LOGL7_ORYSJ
Sequence: MGDGAEAAGATAASRFGTICVFCGSNAGRRRVFGDAALDLGHELVRRGVDLVYGGGSIGLMGLIARTVLDGGRRVVGVIPRALMAVEISGESVGEVIVVQDMHERKAEMARRSKAFIALPGGYGTMEELLEMITWCQLGIHDKPVGLLNVDGYYDPLLALFDKGEAEGFINSDCRQIFVSAPTASELLTKMEQYTRLHQEVAPATSWEISELGYGRTPGADQS
What is the function of this protein?
Cytokinin-activating enzyme working in the direct activation pathway.  Phosphoribohydrolase that converts inactive cytokinin nucleotides to the biologically active free-base forms (By similarity).
What are the official names of this protein?
Probable cytokinin riboside 5'-monophosphate phosphoribohydrolase LOGL7, Protein LONELY GUY-like 7.
What is the protein family that this protein belongs to?
Belongs to the LOG family.
Protein: COR2B_MOUSE
Sequence: MTVTKMSWRPQYRSSKFRNVYGKAANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKVVFKAPIREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRLRQLQLELKNLRNNPKNC
What is the function of this protein?
May play a role in the reorganization of neuronal actin structure.
What are the official names of this protein?
Coronin-2B.
What is the protein family that this protein belongs to?
Belongs to the WD repeat coronin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FMT_MYCBP
Sequence: MRLVFAGTPEPALASLRRLIESPSHDVIAVLTRPDAASGRRGKPQPSPVAREAAERGIPVLRPSRPNSAEFVAELSDLAPECCAVVAYGALLGGPLLAVPPHGWVNLHFSLLPAWRGAAPVQAAIAAGDTITGATTFQIEPSLDSGPIYGVVTEVIQPTDTAGDLLKRLAVSGAALLSTTLDGIADQRLTPRPQPADGVSVAPKITVANARVRWDLPAAVVERRIRAVTPNPGAWTLIGDLRVKLGPVHLDAAHRPSKPLPPGGIHVERTSVWIGTGSEPVRLGQIQPPGKKLMNAADWARGARLDLAARAT
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: OMPX_ECOL6
Sequence: MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF
What are the official names of this protein?
Outer membrane protein X.
What is the protein family that this protein belongs to?
Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpX family.
What are the subcellular locations of this protein?
Cell outer membrane; Multi-pass membrane protein.
Protein: CL056_MACFA
Sequence: MACPLQSGFPARTNSRLDVFLRRHLPPEAYDAVRAYEPCIVVSNSENHTLKYVVLSDRLIYLTENPPKSIRRVVALRDVVAIDLIDDYPEFLSSPDGEISQHIRIIYSSTVLKKECKKSKGVRKFLFPFHHTKANNEKVKEEKNGLAFWRIKEPRSLNESPLRDQQESSTPSKNSTLCPRPGVQKLSLHGQGAFRPLPSPSRRSSQSAPATGKAVSEPSCTTNTKEPQGLPDHNNSISEIPFKCSGNGNEFYLGNSLLDSPSQSNSNLEKKESELHLYVISTTSSIFLHLKSSWNNYNIKATLLQDPFYASKFSPAIGSQKPYRSEEKIKHFSQLKSELFLKDNSLRRILPLIMELKVAAQKNFILKRLFWKTSDLFYFLVNKLHEYLPESRDKNALQNQSQRVDELVACIEIIQTLVLMFRETETESSRLNTLAAKKGTLFNLLVILISEPQIPKSCPVFDIQLVADSALVRMSFDAKLQKLILEYTNTATALLYEILLVFQQGNLGLGSRKFAISWMMSFLQSCPPIITFVASIVKQVVRGLSASFQLLTPCQAVLLYQQFYILKSCLQHSRTLAEYIKNNYREEFRYFIHMPALQKRLPLCYPITQHTTQLFHEVLKLVE
What are the official names of this protein?
Uncharacterized protein C12orf56 homolog.
Protein: CYH2_CHLAE
Sequence: MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP
What is the function of this protein?
Acts as a guanine-nucleotide exchange factor (GEF).  Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6.  Promotes the activation of ARF factors through replacement of GDP with GTP.  The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane (By similarity).  Involved in neurite growth (By similarity).
What are the official names of this protein?
Cytohesin-2, PH, SEC7 and coiled-coil domain-containing protein 2.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm. Cell projection. Cell projection, growth cone. Note=Recruited to the cell membrane through its association with ARL4A, ARL4C and ARL4D. Requires also interaction with phosphoinositides for targeting to plasma membrane. In differentiating neuroblastoma cells, colocalizes with CCDC120 in both neurite shaft and growth cone areas.
Protein: YFIQ_BACSU
Sequence: MQIKEIFMIRCISCLSVVLLHIISMVLMLQAEALADISHTVDSFRTLLMFSTPAFIFISEFLLARSYPDGVPDGFLKKRGKVIFVPFLFIAAIDALLMTSAMGGEVTFLAFVQKYLANVFLGNFIGYFILVIFQFYMLHMMFHEYLKKASPKWVLSISFVVTAAYLGYFSAASPAPASEEGGAFPFFWVPFAGWLFYFCLAYYCGKEYKRFLALLNQYRWVVYGAAIASGALVVTVSYVGEIGMISSKRPDIMLYSTSMIFLCFHLFSKMKHVPKIMMFISNYSFSIYLLHAYFMIIGYVLLLNMPEIPAVPAVLLLFAVCTAGPIMTSWALNKFKYGYLFVGKIYQPKQKKVTVEVRDHAG
What are the official names of this protein?
Putative membrane-bound acyltransferase YfiQ.
What is the protein family that this protein belongs to?
Belongs to the acyltransferase 3 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MURA1_CALS4
Sequence: MKTKFVVEKSPPLKGTVKISGAKNSVLPIIAASLLSSDEVILEDIPSLEDVNVMIELIKNFGALCELDNGKLKIKVDIKDVEAPYELVKKMRASFLVMGPILAKLGHAKISMPGGCAIGARPIDLHLKGFQSLGADITIGHGYVEARAKKLTGKKIYLDFPSVGATENIMMAAVFADGVTVIENAAEEPEIVDLANFLNKMGANIKGAGTDTIRIEGVKELKGAEHTVIPDRIEAGTFMVAAAMTGGNVLIENVIVDHVRSVIAKLTECGVKITEEKGGLRVKGVKNYKAVDIKTLPYPGFPTDMQAQMMAMMTVAKGTSVIIETVFENRFMHVSELKRMGANIKIEGRSAMITGVDHLTGAEVKATDLRAGAALVLAGLIAEGRTEINDIYHVDRGYVKMEEKLRALGAKIYRK
What is the function of this protein?
Cell wall formation.  Adds enolpyruvyl to UDP-N-acetylglucosamine.
What are the official names of this protein?
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1, Enoylpyruvate transferase 1, UDP-N-acetylglucosamine enolpyruvyl transferase 1, EPT 1.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family. MurA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPP_SYMTH
Sequence: MSRVVVIDHPLIQHKLSIIRDKDTGPKEFRELVNEIAMLMAYEVTRDLPTEEVEVDTPIARARCRRLAGEKLGLIPILRAGLGMVQGILSLYPTARVGHIGLYRDPDTLKPVEYYCKLPTDLGERELLVLDPMLATGGSVVASLDLIKRQGGRRIKLLCLIAAPEGVQAVQEAHPDVDIYLAALDEMLNEHAYIVPGLGDAGDRLFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: DNAJ_LYSSC
Sequence: MEKRDYYEVLGLTKSATKDEIKKAYRKLSKQYHPDLNKEPGADEKFKEIAEAYEVLSDDQKKARYDQFGHEDPNAGFGGGFGGGGFGGFEDIFSSFFGGGGRRQDPNAPRKGDDLQYRMNIKFEEAIFGKETEIEIPKDETCETCHGSGAKPGTQPETCSTCNGAGQINQAVDTPFGRMMNRRSCTTCHGTGKIIKEKCSTCRGEGKVQKRKKIKVSIPAGVDDGQQIRVSGQGEPGINGGPAGDLYIMFRVQGHNDFERDGDDIYFELKLTFPQAALGDEIEVPTVHGKVKLRIPAGTQSGAQFRLKDKGVKNVHGYGMGNQYVTVKVMTPEKLTEKQKQLLREFAEISGDIPEEQGSSLFDKIKKKFQGE
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTNC_STRMK
Sequence: MQPRVILTDIEGTTSSISFVKNVLFPYARKALPAFVAEHGQQPEVRRWLDAVATEIGGACQDSLVAETLQGWIDQDRKHTALKALQGLIWDEGYRRGDYTAHFYPEVAPVLKGWHAAGLPLYVYSSGSVPAQKLFFGFSDAGDLSPLVSGWFDTEIGGKREADSYRRIVQAIGVPAGEIVFLSDVVEELDAAREAGLQTRLIDRLDDYPMPRIGQAANGHERVENFQQIQL
What is the function of this protein?
Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
What are the official names of this protein?
Enolase-phosphatase E1, 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
What is the protein family that this protein belongs to?
Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
Protein: RL22_BACAA
Sequence: MQAKAVARTVRIAPRKVRLVVDLIRGKQVGEAIAILNHTPKTASPVVEKVLKSAIANAEHNYEMDINSLVVEKVFVDEGPTLKRFRPRAMGRASQINKRTSHITVVVSEKKEG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: DNCH_SYNR3
Sequence: MRFGETDAAGVLHFQQLLRWCHEAYEESLERFGLEPATLFPTPGQQLNLLLPITHCSADFLAPLICGDPLAIALTPQWLDPTAFEVAYSFSSAGRPVARGLTRHQCIAAADRRRAPLPEGVQRWLQASVQT
What is the function of this protein?
Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis.
What are the official names of this protein?
1,4-dihydroxy-2-naphthoyl-CoA hydrolase, DHNA-CoA hydrolase, DHNA-CoA thioesterase.
What is the protein family that this protein belongs to?
Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily.
Protein: ILVC_BUCDN
Sequence: MNYFNTLNFRQKINQIKKCRFMEKKEFNKKNEILKNKKIVIVGCGSQGLNQGLNMRDSGLNISYALRKNSILKKNQSWINATKNNFLVGDYESLIPNADLVINLTPDKQHSNVVKELQKLMKKDACLGYSHGFNIVEKLRNIRKDITVIMVAPKCPGTEVREEYKRGFGVGTLIAVHNENDYSNMGLEVAKAWAFSTGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQTASLVCYEKLITTQNHPGYAGKLIQFGWETITESLKHGGITLMMDRLSNSSKIRAFKLSQEIKEFSQNLFQKHMDDIISGDFSSKMIQDWKNKDQNLLNWRYKTKNTSFEQSPDYDKKILEQEYYDHGILMVAILKAGIELSFETMIQSGIMEESAYYESLHELPLIANTIARKKLYEMNMVISDTAEYGNYLFSESAYPILKEFVKNINNTDLGSALPRNSVNNIELYNVNTMIRNHPIEIIGRKLRSYMKNMKTIIVG
What is the function of this protein?
Involved in the biosynthesis of branched-chain amino acids (BCAA).  Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate.  In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB).  In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
What are the official names of this protein?
Ketol-acid reductoisomerase (NADP(+)), KARI, Acetohydroxy-acid isomeroreductase, AHIR, Alpha-keto-beta-hydroxylacyl reductoisomerase, Ketol-acid reductoisomerase type 2, Ketol-acid reductoisomerase type II.
What is the protein family that this protein belongs to?
Belongs to the ketol-acid reductoisomerase family.
Protein: CAP14_ARATH
Sequence: MRRKMKLWRRVSGAIKDKLSLITATDEKFTAAVIKATSHNDVSMDIENVQFIYRYIQSNPSSFKPIIRAVSLRVEHTRNWTVALKCLMLLHGLFFSGIMTVDSIGRLPFDLSGFGRRKSRFSRTGRFNIFVRAYFMFLDERSILYYNKNMIRLEIIVKMQRIVDSLMRIKPIGETPLVIEAMEYVISEVVLINGHICRGFAGFLSDVQSNMLEISSAEADLAMNIVAKSLSQREKLFKYFEFCRGFGVTNAQETSNILRITESQMIVLDKLLHIAPELDWKAAKVTPVTAADMVDLVTSEERSNTPSDFLTF
What are the official names of this protein?
Putative clathrin assembly protein At2g01920.
What are the subcellular locations of this protein?
Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Colocalized with clathrin in the Golgi area.