PharMolix/UniProtQA huggingface dataset:
Protein: RNH2_NOVAD
Sequence: MVTIGVDEAGRGPLAGPVVAAAVVLCKPRPSGLDDSKKLSAARRAELEEKIKRRCRWAVGVVEPDEIDRLNIFGATMLAMTLAVGALCEQLAHDEDVGEVLVDGNLTPHGRRPEWCWPARPIVGGDALEPCISAASIIAKEHRDRLMREAALAHPHYGWERNAGYGTPEHLAALREHGPTPLHRRSFAPVAQLQLL
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS13_GEOUR
Sequence: MARIAGIDLPRNKRIEIALTYIYGIGRSTAQKILADAGVDSNTRSDNLTESEIARIRENIDKNVKVEGDLRRDISMNIKRLMDLGCYRGLRHRKGLPVHGQRTKTNARTRKGPARTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: METK2_DIACA
Sequence: MAAAADTFLFTSESVNEGHPDKLCDQISDAVLDACLAQDAESKVACETCTKTNLVMVFGEITTKANVDYEKIVADTCREIGFVSPDVGLDADNCKVLVYIEQQSPDIAQGVHGHLTKRPEDIGAGDQGHMFGYATDETPELMPLSHVLATKLGARLTEVRKNGTCAWLRPDGKTQVTVEYYNENGAMVPIRVHTVLISTQHDETVTNDEIAADLKEHVIKPVIPEKYLDENTIFHLNPSGRFVIGGPHGDAGLTGRKIIIDTYGGWGAHGGGAFSRKDPTKVDRSGAYIARQAAKSIVASGLARRCIVQISYAIGVPEPLSVFVDTYGTGKIHDREILKIVKENFDFRPGMIAIALDLKKGGNRYLKTAAYGHFGREDPDFTWEAAKTLKWEKPQA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine from methionine and ATP.  The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
What are the official names of this protein?
S-adenosylmethionine synthase 2, AdoMet synthase 2, Methionine adenosyltransferase 2, MAT 2.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS2_MYCCT
Sequence: MSREITREELSAAGVQYGHQTKRWNPKMKSYIYGVKNKNHIIDLEKTITHLNAAQKLLEFLGSKQQKILFVGTKRSGKNAVKEAALRSGNFYINNRWLGGTLTNLKTILIRIKALWEIEEEEKKGRLSLRTKKEQIKILKEKAKLEKALGGIKQMHKLPAAIVVVDPKGDEIAVKEAKKLNIPVIAICDTNADPDMVDYVIPGNDDLQESVNLIINILVEAYAEGAQIKMNPSVLRTVAPKREPRQINRPVMSSENQAEQQTSVANENVQMTNEPVVQVAEVEKPSEPKAE
What are the official names of this protein?
30S ribosomal protein S2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS2 family.
Protein: EFTU_BACC7
Sequence: MAKAKFERSKPHVNIGTIGHVDHGKTTLTAAITTVLAKAGGAEARGYDQIDAAPEERERGITISTAHVEYETETRHYAHVDCPGHADYVKNMITGAAQMDGGILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLSEYGFPGDDIPVIKGSALKALQGEADWEAKIIELMAEVDAYIPTPERETDKPFLMPVEDVFSITGRGTVATGRVERGIVKVGDVVEIIGLAEENASTTVTGVEMFRKLLDQAQAGDNIGALLRGVAREDIQRGQVLAKSGSVKAHAKFKAEVFVLSKEEGGRHTPFFANYRPQFYFRTTDVTGIIQLPEGTEMVMPGDNVEMTIELIAPIAIEEGTKFSIREGGRTVGYGVVATIVE
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor Tu, EF-Tu.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOLD_ECO55
Sequence: MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: MODC_PECAS
Sequence: MLQLDFHQQLGSLELHVQSELPANGITAIFGVSGAGKTSLINAVVGLTRPDGGRIVLNDHVLVDTQQRVFLPPEKRHIGYVFQDARLFPHYRVRGNLRYGMAEKMASQFDDIVNLLGIEHLLNRYPLTLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAKEVNIPILYVSHSLEEIVRLADHVVVLDKGKVKAQGLLEEVWASSALRPWLPKDEQSSILSVRVLAQHEHYAMTALALDDQQVWVGKVELAQDAVLRIRVNAADVSLVLQPPEKSSIRNVLRASVEECIDVDGQVEVKLAVGQQTLWSRITPWARDDLALHPGQMLYAQIKSVSITA
What is the function of this protein?
Part of the ABC transporter complex ModABC involved in molybdenum import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Molybdenum import ATP-binding protein ModC.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PLSX_STRPI
Sequence: MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIKQYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTGALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSFYAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVADVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLNYSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: APT_SPHAL
Sequence: MIALPPQPDLDLASLVRTIPDFPRPGIQFRDITTLIGDAVGFAESVRRLSACAAAYRPDLIVAVEARGFLFGAAMATAMGLGVVPVRKAGKLPGVTIGVDYELEYGTDRLELHEGAVLPGHRVVLVDDLLATGGTILATAALMRSVGAEVAAALFVIDLPDLGGSARLGAAGLRCETLIAFNGD
What is the function of this protein?
Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
What are the official names of this protein?
Adenine phosphoribosyltransferase, APRT.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR19_MARPO
Sequence: MTRSIKKGPFVADHLLKKIENLNLKKEKKIIITWSRASTIVPTMIGHTIAVHNGQEHLPIYITDRMVGHKLGEFAPTRTFRGHAKNDKKSRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1301_BRUA2
Sequence: MAKKKDTPGDGEFPGFSDTLQRTPKLEKPHYAGHRDRLKQRFRDAPDALADYELLELLLFRAIRRADTKPIAKALLNRFGSIAEVLAAPENLIAEIPGAGPTVALELKLVEAIAKRSARSTVMEREVLGSWDKVINYCTAAMAFETREQFRILFLDKKNKLIADEVQQTGTVDHTPVYPREVVKRALELSATAIILVHNHPSGDPTPSRADIDMTKQLVNAAKALNITVHDHVIIGKHGHASLRSLRLI
What are the official names of this protein?
UPF0758 protein BAB1_1301.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: BRE1_CAEBR
Sequence: MMKRNNEGIGGEGVANSPPDDTQQKRRRIQFEAVKMPAVQSVTELRSRTVAIQAAKLRQTVLIKNKRISDLERENERAKRRQLTDESNFLKVYNLFSELEKFIWAQTKDEFGEVKMTPSAPAGTDVQGMTSEQYHSFVDTAKGNLRIAFNSYAKARHDRTTETANFIARLKTLMADPKLNINDIHKELAAKTASLLAQIDKLQAEAHRVQSENHNLERKRRHMVDKNTLLESRIQEMEKLLEEAHFETEKQMRLACKYEARLILEHEAASGNATASSSATLNQSEKKMGSPGSPPSESTSREIEALRADRDEQAAIAARRLQELEDTNRKLQSMAQDISKLKMETQSSVPSDVITNSEEYRNLKKYYSLAIKEHERICKDLEDVTVERDQLRSVKENREKMMSEEHQKTIKEIQHQSEIHNTFYRVSHDSEVLRAEFETVKEEYNKTVKQSEWDEMKATVNTLRSLNKTMKSQMQRMKDREKASQKEHSAVKTELKTLKDQLEKSVLVPLEDSGNTSTEDANKIRAEYESLKREIRRIGAMDKQEKQRQLDREIQRHIADKVTELETLRKTNEALTNDEQTLSDELEVVCLTIEEEQERNAQLFMEKRDQEDRNLKMMNERMIQNQVQSRMREKLECLESKAQTDAQIAKMHEFEKKASDEVLNKLTENLQFKTSEVTRLSNMMEVHRKQTQELGFARDENQVKVDRCEAQLKQYQDLYGSKSREVEEAKFKRQRAEEELELVRVKYERAKRNDSAQTGDQVLQEANRQMKETLTCPSCKTRPKDCIMLKCYHLFCETCIKTMYDTRQRKCPKCNSNFGANDFHRIFI
What is the function of this protein?
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-117' of histone H2B (By similarity).  H2B 'Lys-117' ubiquitination gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (By similarity).  Involved in regulating stem cell proliferative fate (By similarity).
What are the official names of this protein?
E3 ubiquitin-protein ligase bre-1, RING finger protein rfp-1, RING-type E3 ubiquitin transferase bre-1.
What is the protein family that this protein belongs to?
Belongs to the BRE1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PI51B_CHICK
Sequence: MSSVTENGDVTAGKPNEEKTYKKTTSSAIKGAIQLGIGYTVGNLTSKPDRDVLMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQNPRTLLPKFYGLYCVQSGGINIRIVVMNNVLPRALKMNFTYDLKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDSETHSALMKTLQRDCRVLESFKIMDYSLLLGIHVLNSNVREKEGESSQNASDGKRPGGQKVLYSTAMESIQGPGKSGDSVVTETTNTMGGIPAKSHKGEKLLLFMGIIDILQSYRLMKKLEHSWKALVYDGDTVSVHRPSFYADRFLKFMNTRVFKKVQALRSSPSKKRCNSITALKATSQEIVSAVSQEWKDEKHSIITEGQSYSSLDEEVLGSRRRPDLVPSTPSLFEAASLATTVSSSSLNVDERYQRDQTMLYSSSKELPSSSTFTLEDSAIYLTSEQSTLETENDNASVLDVYL
What is the function of this protein?
Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4)P/PI4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2), a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility (By similarity).  PtdIns(4,5)P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3), diacylglycerol (DAG) or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3/PIP3) (By similarity).
What are the official names of this protein?
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta, PIP5K1-beta, PtdIns(4)P-5-kinase 1 beta, Phosphatidylinositol 4-phosphate 5-kinase type I beta, PIP5KIbeta, Type I phosphatidylinositol 4-phosphate 5-kinase beta.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cell membrane. Endomembrane system. Note=Associated with membranes.
Protein: Y1794_LISW6
Sequence: MDNGLFIVVTIFVVNILYVTIYTVRLLLTMKGYRYLAALSSVFEMIIYVVALSLVLDNLNNIANVLAYAIGFGVGVIVGMKIEERIALGYITVNVITKEYNLDLPNQIRDLGYGVTSWIASGRDGERMMLEILTQRKNERKLYKQIIEIDNGAFIVSSEPKQIHGGFWIKQVRK
What are the official names of this protein?
UPF0316 protein lwe1794.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: EPHB3_DANRE
Sequence: PLLVLDLIIQERGESFSHTVTAQHTSAKVEGLKAGTVYSVQVRARTVAGYGRYSNPVDFSTSLYVCPVSSSSTSMHLRRREELTTTTTGLKSREERFQKSDDPERSVQDLLPLIVGSASAGFVVILAMIVIAVVCLRRQRTGSELEYTEKLQQYVSPGVKVYIDPFTYEDPNEAVHEFAREIDISCVKIEEVIGAGEFGEVCRGRLKQAGRKETTVAIKTLKAGYTEHQRRDFLSEASIMGQFDHPNVIHLEGVLTRSCPVLIVTEFMENGALDSFLRLNDGRFTVTQLVGMLRGIAAGMKYLSDMNYVHRDLAARNVLVNSNLVCKVSDFGLSRFLDDNSSDPTYTSSLGGKIPIRWTAPEAIAFRKFTSASDVWSYGIVMWEVMSFGERPYWDMSNQDVMNAVEQDYRLPPPMDCPAVLHQLMLECWVKERNMRPRFGQIVSTLDKFLRNAASLKVLTSTHSGDLCRIGGTLPGHQRKSIGDAQDIKQQMSQTLPIRV
What is the function of this protein?
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling.  Generally has an overlapping and redundant function with EPHB2.  Like EPHB2, functions in axon guidance during development.  In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses.  May control other aspects of development through regulation of cell migration and positioning (By similarity).  May play a role in early pattern formation within the developing nervous system.
What are the official names of this protein?
Ephrin type-B receptor 3, EPH-like kinase 3, Tyrosine-protein kinase receptor ZEK3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Cell projection, dendrite.
Protein: MUTL_XANC5
Sequence: MAIRQLPEILINQIAAGEVVERPASVVKELVENALDAGATRVDIELEEGGVRLIRIRDNGGGIAPDELPLAVSRHATSKIASLDDLETVATLGFRGEALPSIASVSRFTLTSRRHDAEHGSALEIDGGRLGEVVPRAHAPGTTVEVRELFFNVPARRKFLRAERTELGHIEEWLRSLALARPDVELRVSHNGKPSRRYKPGDLYSDARLGETLGDDFARQALRVDHSGAGLRLHGWVAQPHYSRASTDQQYLYVNGRSVRDRSVAHAVKMAYGDVLFHGRQPAYVLFLELDPARVDVNVHPAKHEVRFREARLIHDFVYRTLQDALAHTRAGVTPNSIGSDGAGDPGATAGGLGNIAGSGVPNHGNAAGSSGSGYNYASWTPSQTPLGLRVDEARAAYSALYAPPPSSAQQSAGMPSMAGTGLPATAQDSGVPPLGYAVAQLHGIYILAENAEGLIVVDMHAAHERIGYERLKNAHDSIGLHAQPLLVPMTLAVGEREADTAEREAETLATLGFEITRAGPQSLHVRSIPALLANAEPEALLRDVLGDLREHGQSRRIASARDELLSTMACHGAVRANRRLTVPEMNALLRDMEATERSGQCNHGRPTWARFTLSDIDRWFLRGR
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is required for dam-dependent methyl-directed DNA mismatch repair.  May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
What are the official names of this protein?
DNA mismatch repair protein MutL.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutL/HexB family.
Protein: ACCC_HALH5
Sequence: MFKKVLIANRGEIAVRIIRTCQKLNIRTVAIYSEADVDSLHVKHADEAFLIGKPPVAESYLKVDTILEVAKQAGVDAIHPGYGLLSENARFARACVEAGISFIGPSPEVIERMGSKIAARTAMQTAGVPVIPGSDVALADEEEAVHLARKFGYPVMLKASAGGGGIGMQLVRNDEEMRKAFAGNQKRATSFFGDGTMFLEKAVENPRHIEVQIAADHHGHVVHLWERDCSIQRRHQKVVEEAPSPFVDEALREKIGQLAVKAAKAIDYRNLGTVECLVDGEKNIYFLEMNTRLQVEHPVTEEITGIDLVEWQLLIAAGEQLPYAQHEIPLQGHAIEVRIYAEDPVTFFPSPGMIKRFTLPEGEGIRHEYAISEGYKVTPFYDPMVAKLIVSADTRGEAIQRLGRALKQYEIEGIKTNIPMLKQVINHPVFQAGEATTAFVTNHLKVKTGRNP
What is the function of this protein?
This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
What are the official names of this protein?
Biotin carboxylase, Acetyl-coenzyme A carboxylase biotin carboxylase subunit A.
Protein: IPYR_YARLI
Sequence: MSTYTTRSIGAPNTLDYKVYIEKDGKPVSAFHDIPLYANAEKTILNMIVEVPRWTNAKMEISKDLALNPIIQDTKKGKLRFVRNCFPHHGYIHNYGAFPQTWEDPNHVHPETKAKGDNDPLDVCEIGETVGYTGQVKQVKVLGVMALLDEGETDWKIIAIDVKDPLASKVNDIEDVERHLPGLLRATNEWFRIYKIPDGKPENQFAFSGECKNKKYADEVIRECEEAWETLIAGKASDDKGISLENTTLENTPTFTASASIPEGQNLAPAPIDQSIDKWFYISGASV
What are the official names of this protein?
Inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RF2_RICPR
Sequence: MRAEIENYIKKIEQSLDLIWRSLDIEALTVRLTELEELTADPNLWNNNANAQTLLREKNNLEEKLNVFNKLKSNLKEILELEAMAEVENDLETLNQIEQDFKKLSIITAKFETECLFSGETDCNNCFLEINAGAGGTESHDWASIMMRMYLRFAERLGFKTKIINMINGEEVGIKSCTIRIIGKRAYGWFKTESGVHRLVRISPFNAAGKRMTSFASSWIYPEIDDDIAITIEDKDLRIDTFRSSGAGGQHVNTTDSAVRITHIPTNTVTQCQSDRSQHKNKAQAMKMLQAKLYKLEMQKRNENVDKQNANKTDNSWGHQIRSYVLQPYQIVKDLRTNYETSDTKGVLDGNLEDFVSASLSMNNSGNKT
What is the function of this protein?
Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
What are the official names of this protein?
Peptide chain release factor 2, RF-2.
What is the protein family that this protein belongs to?
Belongs to the prokaryotic/mitochondrial release factor family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GPPA_KLEP7
Sequence: MSSTSLYAAIDLGSNSFHMLVVREVAGSIQTLSRIKRKVRLAAGLNSDNTLSAEAMERGWQCLRLFAERLQDIPPTQIRVVATATLRLAVNAGEFLAKAQEILGTPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSLSMGCVTWLERYFADRSLTKENFDLAEAAAREVLLPVADVLRYHGWKVCVGASGTVQALQEIMMAQGMDERITLAKLQQLKQRAIQCGRLEELEIEGLTLERALVFPSGLAILIAIFSELNIQCMTLAGGALREGLVYGMLHLSVEQDIRSRTLRNIQRRFMIDTEQAQRVGGLASHLLSQLDGSWELDPLSRDLLLSACALHEIGLSVDFKRAPQHAAYLVNNLDLPGFTPAQKKLIATLLLNQTNAIDLSSLHQQNAVPPRVAEHLCRLLRLAILFASRRRDDLLPAIQLTAQDEQLTLILPGNWLDEHPLGREMVDQECQWQSYVHWILRVASGDTLK
What is the function of this protein?
Catalyzes the conversion of pppGpp to ppGpp.  Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the 'stringent response', an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities.
What are the official names of this protein?
Guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase, Guanosine pentaphosphate phosphohydrolase, pppGpp-5'-phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family. GppA subfamily.
Protein: XNI_PSYIN
Sequence: MISTLLIIDAMNLVRRIYAVQQKQHGDTPTALIATQSTTTNALKKLLRIHQPTHAICVFDSHAPSWRHQIYPEYKQGRKPIPELLKQGLPAIQEQFFDLGIDSLVTEEDEADDLIACLADKIAKQQQKCIIVSTDKGFYQLLNESIQLYDYFQNSFVIRQQVHQKMGISIQQLNDYWAITGISSSAIKGVEGIGSKGALSLLQQYGSLNNIFQQAEDSNNKLLTKIKSQQSNAILAKQLVTLKTDIKLGFNLKDLRYTDSTD
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: RNPA_YERPA
Sequence: MVKLAFPRELRLLTPSHFTFVFQQPQRAGTPQITILGRLNELGHPRIGLTVAKKHVKRAHERNRIKRLTRESFRLHQHALPSMDFVVLVKKGVADLDNRALTEALEKLWRRHCRQAPAS
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PSBF_IPOQU
Sequence: MTIDRTYPIFTVRWLAVHGLAVPTVFFLGSISAMQFIQR
What is the function of this protein?
This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Cytochrome b559 subunit beta, PSII reaction center subunit VI.
What is the protein family that this protein belongs to?
Belongs to the PsbE/PsbF family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: MNHF1_STAA9
Sequence: MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQLMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD
What is the function of this protein?
Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion.
What are the official names of this protein?
Na(+)/H(+) antiporter subunit F1, Mnh complex subunit F1.
What is the protein family that this protein belongs to?
Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMN_SPICI
Sequence: MTSIFGYPKEELQLDLVAHGFKKYLAEQIFDWIYVKNIYSFDEMTNISKTDRNKLQEYYTIEPLKIVVQQQSKDWTVKFLFQLADGYKIETVLMPQSYGNSVCVTTQVGCNMACTFCASGLLKKTRNLSTAEIVQQVMMVNRYLATTNERVSHIVVMGIGEPFDNFDNTLKFVNIINDPKGYQIGARHITISTCGLVPKIKQFAELKTQVNLAISLHAPNNTIRNQLMPINKAYPVEKLMDAVRYYIELTNRRVTFEYILIENVNDSRETALELAKLIRGLNAYVNLIPYNTVAENGHQRSTKINKFFETLQQQKINCIVRREFGHDIDAACGQLRAKNEGVIRK
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADF12_ARATH
Sequence: MANAASGMAVEDECKLKFLELKAKRNYRFIIFRIDGQQVVVEKLGSPQENYDDFTNYLPPNECRYAVYDFDFTTAENIQKSKIFFIAWSPDSSRVRMKMVYASSKDRFKRELDGIQVELQATDPSEMSLDIIKSRAL
What is the function of this protein?
Actin-depolymerizing protein.  Severs actin filaments (F-actin) and binds to actin monomers.
What are the official names of this protein?
Actin-depolymerizing factor 12, ADF-12, AtADF12.
What is the protein family that this protein belongs to?
Belongs to the actin-binding proteins ADF family.
Protein: YGEN_ECOLI
Sequence: MRKKIEMSLIKSPANGVVIKRKISDGLKEIVSLKEKILLETTAKIQSIEEKREEKFIQGYYDGYTKGIIDEMDNFIPLISLLCSELEKKRINMINDLKSILLKPSEEVDVFIKIFESWVTKLPSISGPVNLHIPTSFKDKSLEVESYFVDKSIWNVHITFHDDKRFVFFTDQFIAEFSPQEFVDNCEQYLINNHCFSPDKVNEICEQARHYLVEKMFETHSLDMNNSVLASPEDL
What are the official names of this protein?
Putative uncharacterized protein YgeN.
Protein: FAKD2_RAT
Sequence: MNNRAHTFLWGIRQFRTSIPRSRALRTYSLVFCKPEVIHSKRNPRNHLLNGFDEGLQPSVRYLFQDIFISKSVAGCTQTRGIIHAAGFKLDRILCPRRLSFDAKHSFVSDGTSDHDLMKTNFHHTSTEDVLTKKMRPTPVNYKKLAQECNSLSDVLDTFSKAPTFPGSNYFLAMWIIAKRISEDKRRFEKQLMFSHPAFNQLCEQMMREAKIMRYDHLLFSLNAIVKLGVPQNSLMVQTLLRTIQERISECDERCLSILSTALVTMEPCMNVNALRAGLRILVDQQVWNINDIFTLQTVMRCIGKDMKALKELGRFSVLNSRHMFEVLAAMDHRSVVLLNECSKIVIDNIHGCPFKVLISILQSCRDLRYQNEDLFKSIADYVATTFDIWKLKHVIFFLLSFETLGFRPPGLMDKLLEKVVQEPGSLTVKNIVSVLHVYSSLNHVHNVQNREFLEALASALTGCLHQISSESLLNAVHSFCMMNYFPLAPINQLIKENIIHELLTSGDTEKNIHKLHVLNTCLKLDESTYKCIHIPLPQLPLTASHPNEKLAEVLSRLLEGDGCFSRNVQLPHNYHIDFEIRMDTNRTQVFSFSEGDASSATNMQRVAVLCVPKSAYCLNSNHLRGLMAMKIRHLNVMGFHVILIHNWELKKLKMEDAVTFVRKKIYSDEALATTDESV
What is the function of this protein?
Plays an important role in assembly of the mitochondrial large ribosomal subunit.  As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.  May play a role in mitochondrial apoptosis.
What are the official names of this protein?
FAST kinase domain-containing protein 2, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the FAST kinase family.
What are the subcellular locations of this protein?
Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid. Note=Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.