PharMolix/UniProtQA huggingface dataset:
Protein: VPH_STRVI
Sequence: MRIIETHRDLLSRLLPGDTVGGLAVHEGQFHHVVIGSHRVVCFARTRAAADRLPGRADVLRALAGIDLGFRTPQPLSEGGAQGTDEPPYLVLSRIPGAPLEDDVLTSPEVAEAVARQYATLLSGLAAAGDEEKVRAALPEAPANEWQEFATGVRTELFPLMSDGGRERAERELAALDALPHLTSAVVHGDLGGENVLWETVDGVPRMSGVVDWDEVGIGDPAEDLAAIGASYGEELLGRVLALGGWADNGTAERISAIRGTFALQQALYAQRDGDEEELADGLSGYR
What is the function of this protein?
The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation.
What are the official names of this protein?
Viomycin phosphotransferase, Viomycin kinase.
What is the protein family that this protein belongs to?
Belongs to the aminoglycoside phosphotransferase family.
Protein: TES_FELCA
Sequence: MDLEAKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKTDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPKEVKEMEQFVKKYKSEALGVGDVKLPREMDTQGPNRMLLPGGDRSTTAAVGAMEGKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSACQELLVDMIYFWKNGKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDNILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKMMS
What is the function of this protein?
Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.  Plays a role in the regulation of cell proliferation.  May act as a tumor suppressor (By similarity).
What are the official names of this protein?
Testin.
What is the protein family that this protein belongs to?
Belongs to the prickle / espinas / testin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell junction, focal adhesion. Note=Detected along actin stress fibers.
Protein: UBID_SHIDS
Sequence: MDVMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLHRIPIMTCWPGDAAPLITWGLTVTRRPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
What is the function of this protein?
Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
What are the official names of this protein?
3-octaprenyl-4-hydroxybenzoate carboxy-lyase, Polyprenyl p-hydroxybenzoate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the UbiD family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: DNAJ_LEGPC
Sequence: MEQRDYYELLEVSRNASDAEIKKAYRRLAMKYHPDRNPGDTSAEEKFKEIQKAYNILSDKQKRAAYDQFGHAGVDPSMGGGPGGFGGFGGFGDVFEDIFENIFSGGRGHGRQSRGQRGADLQFNVQLTLEEAAIGKEVEITVPRHGTCTVCEGSGAKKGTSPKTCETCQGMGQVRIQQGFFSIQQTCPTCHGEGKIISDPCASCHGQGRVRESKKINVKIPAGVDNGDRVRLSGEGEAGVHGGGSGDLYVQISLKKHAIFERHENDLHCEVPISFATAALGGSIEVPTLEGRVTLKIPAETQTGKVFRLRSKGMKSVRGYGQGDLLCKVVVETPVNLSREQKELLNKLQDSLENAKGTHSPKTSSWFAGVKKFFEDMKF
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.  Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
What are the official names of this protein?
Chaperone protein DnaJ.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPE_ARTGO
Sequence: MQDLGIISPGLEEFRELAAHSRVIPVRLKVLADAETPIGLYRKLAQGQPGTFLMESAAVGGAWSRYSFIGSRSRATLTTKDGQAHWLGEPPAGVPVDGNPVDAIRDTIEALRTDRFDGLPPFTSGLVGFLGWETVRHWEKLTRPPEDDLQLPELALNLVTDMAVHDNMDGTVLLIANAINFDNSSERVDEAWHDAVARVKELLARISTPVLQPVSVLEPAALDFAASVQERWNEPEYLAALDRGKEAIVDGEVFQVVISRRFEMECGASPLDVYRVLRNTNPSPYMYIFSLEDAAGRQYSIVGSSPEALVTVTGEDVITHPIAGSRPRGKTVDADKALAEELLADQKERAEHLMLVDLSRNDLSKVCVAGSVDVTQFMEVERFSHIMHLVSTVVGRLAPTAKAYDVLKATFPAGTLSGAPKPRALRLLDELEPHRRGIYGGVVGYLDFAGDMDMAIAIRSALLREGRAYVQAGGGIVADSSNPAEAQETVNKAAAPLRAVHTAGSLHNITPDSVSAPDSVSSPDSVTEANS
What is the function of this protein?
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan.  In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate.  In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity).
What are the official names of this protein?
Anthranilate synthase component 1, AS, ASI.
What is the protein family that this protein belongs to?
Belongs to the anthranilate synthase component I family.
Protein: LBH_XENLA
Sequence: MSVFYPIHCTDYLRSAEMTEVIMNTQSMDEIGLSPRKDSYQIFPDPSDFERCCKLKDRLPSIVVEPTEGDVESGELRWPPEEFVVDEDKEGTCDQTKKENEQ
What is the function of this protein?
Transcriptional activator.
What are the official names of this protein?
Protein LBH, Cleavage 2 protein, XLCL2.
What is the protein family that this protein belongs to?
Belongs to the LBH family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: Y2323_STAA1
Sequence: MLYPIFIFILAGLCEIGGGYLIWLWLREGQSSLVGLIGGAILMLYGVIATFQSFPSFGRVYAAYGGVFIIMSLIFAMVVDKQMPDKYDVIGAIICIVGVLVMLLPSRA
What are the official names of this protein?
UPF0060 membrane protein SAHV_2323.
What is the protein family that this protein belongs to?
Belongs to the UPF0060 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: KDSB_SHEPW
Sequence: MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERASLAKGLTDIYVATDDDRIKDAVEGFGGKVVMTSAEAASGTDRIEDAITQLGLAEDDLVVNLQGDQPLIDPISIEQIISLFERHPGEFGMATLGFQITEEEELNDPKHVKLVFDNEFNALYFSRARIPFGRDTDDYPVYKHLGVYAYTRKFVQTFAKLPLGRLEDLEKLEQLRALEHGHKIKVAISAFDSPEVDTPEDIRICEARLAVD
What is the function of this protein?
Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus.
What are the official names of this protein?
8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase, CMP-8-amino-3,8-dideoxy-manno-octulosonate synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HNRPQ_HUMAN
Sequence: MATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKLYNNHEIRSGKHIGVCISVANNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAAQARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQFGKLERVKKLKDYAFIHFDERDGAVKAMEEMNGKDLEGENIEIVFAKPPDQKRKERKAQRQAAKNQMYDDYYYYGPPHMPPPTRGRGRGGRGGYGYPPDYYGYEDYYDYYGYDYHNYRGGYEDPYYGYEDFQVGARGRGGRGARGAAPSRGRGAAPPRGRAGYSQRGGPGSARGVRGARGGAQQQRGRGVRGARGGRGGNVGGKRKADGYNQPDSKRRQTNNQNWGSQPIAQQPLQGGDHSGNYGYKSENQEFYQDTFGQQWK
What is the function of this protein?
Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms.  Component of the CRD-mediated complex that promotes MYC mRNA stability.  Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes.  Isoform 1 binds to apoB mRNA AU-rich sequences.  Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself.  May be involved in translationally coupled mRNA turnover.  Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.  Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences.  Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins.  Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.  Upon interferon-gamma activation assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation; seems not to be essential for GAIT complex function.
What are the official names of this protein?
Heterogeneous nuclear ribonucleoprotein Q, hnRNP Q, Glycine- and tyrosine-rich RNA-binding protein, GRY-RBP, NS1-associated protein 1, Synaptotagmin-binding, cytoplasmic RNA-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm. Microsome. Endoplasmic reticulum. Nucleus. Note=The tyrosine phosphorylated form bound to RNA is found in microsomes (By similarity). Localized in cytoplasmic mRNP granules containing untranslated mRNAs (By similarity). SUBCELLULAR LOCATION: [Isoform 1]: Nucleus, nucleoplasm. Note=Expressed predominantly in the nucleoplasm. SUBCELLULAR LOCATION: [Isoform 2]: Nucleus, nucleoplasm. Note=Expressed predominantly in the nucleoplasm. SUBCELLULAR LOCATION: [Isoform 3]: Nucleus, nucleoplasm. Note=Expressed predominantly in the nucleoplasm.
Protein: LOLB_SHEAM
Sequence: MINLRRFTKFTLAGLTALSLLGGCSVTPKVALQPVSVENASDAKAWELKGKLLIRTNGDKVSANLFWLNTPDNAELRLTSMLGTTVLLLTQNRDGATLEVDGKRYSDLSPQRLLDGLSGFTLPIDALPFWITGQPMAGDEVEFDTLNRPKTIISADGEWTINISSWQTQSGAPVPRMLELTHASAVIKLQTNEWQALANATGSKGAR
What is the function of this protein?
Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
What are the official names of this protein?
Outer-membrane lipoprotein LolB.
What is the protein family that this protein belongs to?
Belongs to the LolB family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: XERC_CORGL
Sequence: MARSGRNAPPSGISGADAPSKLHTLIDDFCEHLDLVVGRSAATIRGYRSDLYAMADTIEDIDNFSLPTLRQWLGIAVDEGKSRATLARRTASVKAFSSWAQKNGHLKADEAARLISPKITRDLPKILGEQQAGDFVENAASTNEEEFLRDSAILELLYATGMRVAELCGIDLSDIDYDRKMVRVLGKGNKERVVPFGESAHKALRNWLDVRDEMTEDPKALFVGVRGQRINARQVRRIVDRAAKVTGVDHLSPHSLRHTAATHLLDGGADLRQVQELLGHSSMQTTQIYTHVSNKRLLEAFNKAHPRA
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYC_AYWBP
Sequence: MLQIYNSLTRKKEFFKPDHPPQINIYVCGPTVYNHLHLGNTRPLIFFDTVKRYLEMLKFKVYYVVNITDIDDKIIETSLKNQVLEKDLANKYIKSFNNLLETLNIQTINFKPQATQYINSMILYIQTLLDQGFAYFTDQGIYFRVSKITDYGKLKKQDLSQLKQNVRKQLDPQKEFPGDFILWKKTSQGITYPSPWFAGRPGWHTECATMIEQLFKLPLDIHGGGTDLKFPHHENEIAQTHAHSHQKLANFFMHVERLDYQNQKMSKSLGNIIWCKDLLKQYNPCIIKFLILSTHYRKPINFSYDLMEQTQQKYKKITYFLTKNNFYLKVNHFFCQTLDQDIMQLFHQLMQDDFATHKVIDLMEQIIKRAHQTQILDKLSQFQNSLLLILNTLVIAIPFNKPTKKDLQTYFLWQDARKCRDFIQADILRKQLLDKGFI
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YE87_SCHPO
Sequence: MDDLLNSVSFSNASNPHNAWGSENISNSNSAIPSITNDVSFSMEASVWKENALNLDTFNLKDINEKLDYTFGVVKPPKRISLASKDYIGITATSETNFRQLIRLGYNEKSLGELKQGTISRLLKEHMTLWNQERSNVNRKSNVLFCWSTAYQKQKRKTASYTNSPVTPPINDKNILLPEQSPLSNFSTTKISSINVPSDILDFSNLSSNEIPKDYSSSTALLNNTVAVKQDHKLSANTFLSSPVKLIERESNSCSTISINKEDEVVPKSPLSLDRKKVDEVEEHSSIAKLDSEEKIRETKKKNSSTSLSPDPTSDNFEWGSWVSSQDTSKNSSNLASASVDDVSEESQVEPNTLIFQNFSSPSTSLSAPKDTPAVIQSINTSFLNNERAGRGNIKTVDQNQLINRIVDKLPDLSYLVD
What are the official names of this protein?
Uncharacterized protein C9G1.07.
Protein: RECA_LISWE
Sequence: MNDRQAALDQALKQIEKQFGKGSIMKLGEHSDQNISTISSGSLALDIALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQAQGGTAAFIDAEHALDPAYAKNLGVNIDELLLSQPDTGEQALEIAEALVRSGAVDMLVIDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGAINKSKTIAIFINQIREKVGVMFGNPEITPGGRALKFYSTVRLEVRRAEQLKQGTDVMGNKTKIKVVKNKVAPPFRIAEVDIMYGEGISREGELVDMAAEVDVINKSGSWYSYKEERIGQGRENAKQYLKEHTDIRDEISQRVREEYEIDGANKEPLEETEETLSLLDDE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF2B_PYRCJ
Sequence: MDDEYLALLDRAYKLVSPKAQRRAEIPKIEVVNMPRKTIIQNFGAIAKRLNRDVYLMAKFFQKELAVPGTVEGDVFTLHGEKSPKVVEAVYERFIKYYVVCPVCNSIDTELRREGRIFVLHCLACGASTPVRPL
What is the function of this protein?
eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.
What are the official names of this protein?
Translation initiation factor 2 subunit beta, aIF2-beta, eIF-2-beta.
What is the protein family that this protein belongs to?
Belongs to the eIF-2-beta/eIF-5 family.
Protein: MEND_HALMA
Sequence: MTAPNVNTLWAETLVGELVAGGVDAVCLSPGSRSTPLTVAFAEHPDIEVFSHLDERSAAFFALGRARRTGEPTPLVCTSGTAAANYHPAVIEANQSGVPLLLLTADRPPELIDSGANQTVDQEKLYGDAVRWYRDMPEPEAEPRKVRMLRTTAARALAESTGSDPGPVHLNCRFRKPLEPTPMPEDDPAGVPADWAGGDNGAKIGRDGPFVTTSEGVETPDEQTVRRVQDALEAAERGLIVAGPADQGLSADSLERLAAATGFPVLADPLSDLRFGPHVDRLDVPVCGGYDGYLGSDSVDQWDDPDVVVRFGASPTSKPLRHYLRDADCQQFLVDPAGGWSEAEFTATNLLVANPDATADALAGETLGGVAASWREQFIRAEQTHWDAVTETASETYWEGGVLSDVTALAPDPATLFISNSMPIRDMDRFGGPRDADLTVLGNRGASGIDGITSTALGAGSATSDPLVLVTGDLAYYHDMNGLLALGRCAVDATVVLLNNDGGGIFHMLPIEDHPTFEDQFRTPHGLDFEPTEALYSLQFERVADRRQFRERFAESVQTDGTQVIEVRFDAGDSHAVRDQLTEQVAETLAGD
What is the function of this protein?
Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
What are the official names of this protein?
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, SEPHCHC synthase, Menaquinone biosynthesis protein MenD.
What is the protein family that this protein belongs to?
Belongs to the TPP enzyme family. MenD subfamily.
Protein: H10_HUMAN
Sequence: MTENSTSAPAAKPKRAKASKKSTDHPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK
What is the function of this protein?
Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures.  The histones H1. 0 are found in cells that are in terminal stages of differentiation or that have low rates of cell division.
What are the official names of this protein?
Histone H1.0, Histone H1', Histone H1(0).
What is the protein family that this protein belongs to?
Belongs to the histone H1/H5 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=The RNA edited version has been localized to nuclear speckles. During mitosis, it appears in the vicinity of condensed chromosomes.
Protein: PROB_ECO7I
Sequence: MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENGB_HALMA
Sequence: MFESRPDRDAEVVLIGRSNVGKSTLMREITGHTFDTGQRPGVTRSPNHFDWASADFVISDLPGFGFMKGVPEDVREEIKTDVVQYVERNAEHILVGILVVDGKSVIDIIDRHSGPDEIPHDVEMFHFLREVGVEPVVAVNKMDKVDDKDARLNELCDRLGLHPPWQQWQETIAPISAKHGSTEPLNEAVRHHLHEVQRDDLFQFF
What is the function of this protein?
Necessary for normal cell division and for the maintenance of normal septation.
What are the official names of this protein?
Probable GTP-binding protein EngB.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
Protein: NDUB8_GORGO
Sequence: MAVARARVLGVQWLQRASRNVMPLGARTASHMTKDMFPGPYPRTPEERAAAAKKYNMRVEDYEPYPDDGMGYGDYPKLPDRSQHERDPWYSWDQPGLRLNWGEPMHWHLDMYNRNRVDTSPTPISWHVMCMQLFGFLAFMIFMCWVGDVYPVYQPVGPKQYPYNNLYLERGGDPSKEPERVVHYEI
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial, Complex I-ASHI, CI-ASHI, NADH-ubiquinone oxidoreductase ASHI subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFB8 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: MSRB3_MOUSE
Sequence: MPPAAPSVARSREGGGIGQRRLVFPKSARRTLPCPIALCLGLCLAAAAATTTRASAAAFASAGDTTAMSAFNLLHLVTKSQPVAPRACGLPSGSCRDKKNCKVVFSQQELRKRLTPLQYHVTQEKGTESAFEGEYTHHKDPGIYKCVVCGTPLFKSETKFDSGSGWPAFHDVISSEAIEFTDDFSYGMHRVETSCSQCGAHLGHIFDDGPRPTGKRYCINSASLSFTPADSSEAEGSGIKESGSPAAADRAEL
What is the function of this protein?
Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine.
What are the official names of this protein?
Methionine-R-sulfoxide reductase B3, mitochondrial, MsrB3.
What is the protein family that this protein belongs to?
Belongs to the MsrB Met sulfoxide reductase family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Note=Not detected in the mitochondrion.
Protein: VE6_HPV48
Sequence: MEPQFPTDLDSYCKYFNISFFDLVLKCIFCKFSVSIVDLASFHNKRLSVIWRDNTPFACCTKCLRLTALYEKDNFFVCTAKSHLLTGLVKKELSDINIRCQHCYSFLDYLEKLYHLYNDVDFLLIRGTWRGVCRNCISHEGR
What is the function of this protein?
Plays a major role in the induction and maintenance of cellular transformation.  E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity.  Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1.  May also inhibit host immune response.
What are the official names of this protein?
Protein E6.
What is the protein family that this protein belongs to?
Belongs to the papillomaviridae E6 protein family.
What are the subcellular locations of this protein?
Host cytoplasm. Host nucleus.
Protein: RS19_ACIAC
Sequence: MTRSLKKGPFVDHHLLAKVEKAVATKDKKPVKTWSRRSMVLPEFIGLTIAVHNGKQHVPVYITDQMVGHKLGEFALTRTFKGHPADKKVQKK
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: NODI_RHILO
Sequence: MLKRKLGPEDLRRLETPAIERESHGQTSAKSSVPDSASTVAVDFAGVTKSYGNKIVVDELSFSVASGECFGLLGPNGAGKSTIARMLLGMTCPDAGTITVLGVPVPARARLARRGIGVVPQFDNLDQEFTVRENLLVFGRYFGMSTRQSEAVIPSLLEFARLERKADARVSELSGGMKRCLTMARALINDPQLIVMDEPTTGLDPHARHLIWERLRALLARGKTIILTTHFMEEAERLCDRLCVLEKGRNIAEGGPQALIDEHIGCQVMEIYGGDPHELLSLVKPHSQRIEVSGETLYCYAPDPDQVRTQLQGRAGLRLLLRPANLEDVFLRLTGREMEE
What is the function of this protein?
Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction.  Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide.  This subunit is responsible for energy coupling to the transport system.
What are the official names of this protein?
Nod factor export ATP-binding protein I, Nodulation ATP-binding protein I.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Lipooligosaccharide exporter (TC 3.A.1.102) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YO6_ADEG1
Sequence: MLLRQTGWVTALLREIVSTMMVAVTVTRHAFMRTTGDRTKGTDEGTCEKDTSKLIERRAIFTDIFSAIRKPVVKNLKSVFLRASIHGSKSYFIPGVIKSNLRER
What are the official names of this protein?
Uncharacterized protein ORF6.
Protein: VP7_ROTHA
Sequence: MYGIEYTTILTILISIILLNYILKTITNTMDYIIFRFLLLIALISPFVRTQNYGMYLPITGSLDAVYTNSTSGEPFLTSTLCLYYPAEAKNEISDDEWENTLSQLFLTKGWPIGSVYFKDYNDINTFSVNPQLYCDYNVVLMRYDNTSELDASELADLILNEWLCNPMDISLYYYQQSSESNKWISMGTDCTVKVCPLNTQTLGIGCKTTDVNTFEIVASSEKLVITDVVNGVNHNINISINTCTIRNCNKLGPRENVAIIQVGGPNALDITADPTTVPQVQRIMRINWKKWWQVFYTVVDYINQVIQVMSKRSRSLDAAAFYYRI
What is the function of this protein?
Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved.  Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors.  Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion.  This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7.
What are the official names of this protein?
Outer capsid glycoprotein VP7.
What is the protein family that this protein belongs to?
Belongs to the rotavirus VP7 family.
What are the subcellular locations of this protein?
Virion. Host endoplasmic reticulum lumen. Note=The outer layer contains 780 copies of VP7, grouped as 260 trimers. Immature double-layered particles assembled in the cytoplasm bud across the membrane of the endoplasmic reticulum, acquiring during this process a transient lipid membrane that is modified with the ER resident viral glycoproteins NSP4 and VP7; these enveloped particles also contain VP4. As the particles move towards the interior of the ER. cisternae, the transient lipid membrane and the non-structural protein NSP4 are lost, while the virus surface proteins VP4 and VP7 rearrange to form the outermost virus protein layer, yielding mature infectious triple-layered particles.