PharMolix/UniProtQA huggingface dataset:
Protein: NSP1_ROTHW
Sequence: MATFKDACYYYKRINKLNHAVLKLGVNDTWRPSPPTKYKGWCLDCCQHTDLTYCRGCTMYHVCQWCSQYGRCFLDDEPHLLRMRTFKNEITKDDLKNLIDMYSTLFPMNQKIVCKFINNTKQHKCRNECMTQWYNHLLMPITLQSLSIELDGDVYYVFGYYDNMNSVNQTPFSFTNLIDMYDKLLLDDVNFVRMSFLPTSLQQEYAIRYFSKSRFISEQRKCVNDSHFSINVLENLHNPSFKVQITRNCSELLLGWNEACKLVKNVSAYFDMLKTSRIEFYSVSTRCRIFTQHKLKMASKLIKPNYITSNHRTSATEVHNCKWCSVNNSYTVWNDFRVKKIYDNIFSFLRALVKSNVNIGHRSSQEKIYEYVEDVLNVCDNEKWKTSIMKVFNCLEPVELDNVKYVLFNHEINWDVINVLVQSIGKVPQILTLKNVITIIQSIIYEWFDIRYMRNTPMVTFTIDKLRRLHTELKTAEYDSGISDVE
What is the function of this protein?
Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7.  Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities.  Recognizes the host NF-kappa-B regulator BTRC through the presence of a DSGXS motif in the C-terminal substrate recognition domain.
What are the official names of this protein?
Non-structural protein 1, NSP1, NCVP2, Non-structural RNA-binding protein 53, NS53.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP1 family.
What are the subcellular locations of this protein?
Host cytoplasm, host cytoskeleton.
Protein: H2B8_CHICK
Sequence: MPEPAKSAPAPKKGSKKAVTKTQKKGDKKRRKTRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2B 8, H2B VIII.
What is the protein family that this protein belongs to?
Belongs to the histone H2B family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL24_CITBB
Sequence: MLGKKLHVKKNDTVVVIAGKDRSKSGKVISIHPKKDGVIVEGVNVVKRHQKPRGSEQGGILEKEAPVHISNVMLLCGKCNKPVRTKTTVLEDGKKARCCVKCGESFDK
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: METL5_CAEEL
Sequence: MPDKKTLWMLNELEGFEKPKIKLEQYATSSELAVSMMEMIDETIGFEGKKLIDIGCGCGMLMTTAATMYELETVLGVDIDDEALKICSRNLETAEVQDRCELLQADILDPESDLPRGTFDVAVINPPFGTKNNAGIDMQFVQIGLQMVRPGGSVFSLHKSSTRDYILKNAKKWDGVGAECCAEMRWQLPATYKFHKQKAVDIAVDLIHFKKLDS
What is the function of this protein?
Catalytic subunit of a heterodimer with TRMT112/C04H5. 1, which specifically methylates the 6th position of adenine in position 1717 of 18S rRNA.
What are the official names of this protein?
rRNA N6-adenosine-methyltransferase metl-5, Methyltransferase-like protein 5.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
Protein: TAGA_VIBCH
Sequence: MVVRYSLLMKVSFAILIFLVGCNENATSSNDQYLTDPDISEQTKKPSRPIIDEKNKGVTDTSVTIEWDKIECEKNFSHYNVIVYRKDRIEDVITIRTRNNSVFIDDLKPNSQYSIDVSSCLHSACSESAKIEFITLNEIDYYHTTEIEKNVYGSLEGEVRFVQTHVISPEGRKNEPEIITGRDALILFKPSIKNSSSILMKIYSEDGLTSKVVMKSPSMLPKTDQPIDIDENNKVVSYSNSYWSAEIPWNKMKSGMSLHFEDENGNLGIIESERIKFSAPSELIIQNIDLGMLYKPRGRNIVIKELERTAVDYFQKVPVSKLIFSDYTPIHFEKITLPNGTVYTEKSADIGGWHQGDMREAVGKALVSTGINNANLGIVASSGYSQQYNRLTNHITAHTNIGYYNNGVVVHGGSGGGGIVTLENTLHNEWSHELGHNYGLGHYVAGGTSHGPDTSWGWDGYYKRFIANFDWKRSPQSNIRPDNQEVVKPFMDKYTYLWDAMSGGYDHQNGIISRYTLHHPYVARIIQDWLKNGAVVINNDYMVWDELKNIYVYKGTNFKVPIKKGVPVVTILGVYDPDKINPSQLYPPTYSNYGNIFDLEKPRSESSLKGWQYVKDVNYLDRVNTHWHTMLVNRKEEKICRFSYLSPKGKKFEFLGYEDIENKICTGGRSIHYLEDGKKNPIESKYNDYFLLSIDGDGEISYVPDSTIGESKICSLKMSGTVYGAGFIKGNSCRQIDGVFMNGFQWAFTLNQSGVNSTYTWSNECVLKIKDKDNNIESISIPNYRIEKNQSNKIHLNISREKPIIDINVYCGEHELTSIKVSDNPDIKLLKGPIIVGQEHGYTSYEPKLPSGWFKHYDNFEPKNEINHELGKMRVNDNDEYICRFNFSDSDREMKFVGYVSQLSESKYICTGGSEIYYKKNEINIELSSKENDFEWLSVRDKNLVGSKIEFDNNKTLCVLDNRSFYGAGYLDENNRCTQDRQIHWSNGKQWLFSTYKTMTYH
What are the official names of this protein?
ToxR-activated gene A lipoprotein.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: PYRH_STRSY
Sequence: MMKPKYERILIKLSGEALAGERGVGIDLKTVQEMAKEIQEVAESGIQIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLKQLGVDTRVQTAIAMQSVAEPYIRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILMAKNGVDGVYNADPKKDANAVKFNELTHREVISRGLKIMDATASTLSMDNDIDLVVFNMNEPGNIKRVVFGEPIGTTVSNSSEEK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRO_ADEE2
Sequence: MGSTETELKRILSDLNVTPLLLGTYDKRFPGFVSKAKPCPIVNTAFGETGGEHWIAMAWYPPNNSFYMFDPFGFSDQKLKQIYDFEYQGLLRRSALTSSKDRCVQLIRSTDTVQGPNSAGCGLFGGLFLKSFACNPARPRNGNPIIDIVRGVPNERFTDPSSLPILYRNQENMYAFLENNSPYFVSHEREIKRKTAFDYIQ
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: CH10_ACET2
Sequence: MNIRPLGDRVVVKMVETEETTKSGIVLPGSAKEKPQVAEVVAVGPGTVVDGKEVKMEVKVGDKVIISKYAGTEVKFDGQEYTILRQNDILAVVE
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CSRA_THISH
Sequence: MLILTRRVGETLMIGDQVSVTVLGVKGNQVRIGINAPKDVAVHREEIYERIKNEGDEGQATGGN
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TAM_YERPY
Sequence: MQDWDPDLYRQFEAERTRPATDLLAHITITSPQFISDLGCGPGNSTELLHRRFPDAQLVGIDHSQAMLASAQQRLPHCTFIEADIHQWRPSQPQNLIYANASLQWLTDHPHLFPSLLSQLAPRGVLAVQMPDNLDQPSHRAMREVAENGPWQQTLQEAGATRAKVLSANHYYDLLAPHAERVDIWRTTYYHPMPSAQAIVDWLRATGLRPYLAPLTEAMQLAFLQNYLAIIDKAYPARTDGRRLLAFPRLFIVAHAQR
What is the function of this protein?
Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.
What are the official names of this protein?
Trans-aconitate 2-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. Tam family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROA_LIMRD
Sequence: MNQDLIAIGKRAQNAANKLALMNTATKNKALLQLADDLIKNKNQIIAANQQDLAAATQMPTKFTDRLMVNSQRIADMANGLRTIADLNDPTSQIDKGWITKDGLQILQRRVPLGVIGIIFEARPNVTVDATGLTFKSGNAVILRGGKEAIQTNTALVKILRESLQSQHLPVDAVQLITDTSHAIADEMMNLTDYIDVLIPRGGRALIQRVVTTATVPVIETGAGNCHIYIDKDADLTMATNITVNAKVQRPSVCNAAEKLLIHRDIAAKFLPVIAKALMEHGVQLRGDETACQLVSTIRPVTEEDWDTEYNDLIMAVKIVDSLDDAISHINHYSTHHSESIITNNITRGRYFQQAINSACVYVNASTRFTDGGEFGFGAEIGISTQKLHARGPMGLQQLTTIKYEITGNGQIRK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate.  The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
What are the official names of this protein?
Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, GSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the gamma-glutamyl phosphate reductase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NSP4_ROTBU
Sequence: MEKLTDLNYTLSVITLMNSTLHTILEDPGMAYFPYIVSVLTVLFTLHKASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVVKEMRRQLEMIDKLTTREIEQVELLKRIHDKLMIRTVDEIDMTKEINQKNVRTLEEWENGRNPYEPKEVTAAM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: LEU1_THENN
Sequence: MRRIKIFDTTLRDGEQSPGASMSVEEKVEMALMLEDLGVDLIEAGFPVSSPVQFEAVKRVAEAVQRPIVVGLARCVEKDIDAAYEALKDRPKDKRMIHVFIATSPIHRKYKLRMEKEEILERVRKYVTYARQFFDLVEFSAEDASRTEVPFLIEVYRTAIESGATTINVPDTVGYALPDEFGELIRTLKEGVPGIENVDLSVHCHNDLGLAVANSIAAVQNGATQVEVTLNGIGERAGNCALEEFVMALKVRKDRLPYETGIRTELIYPASRLLTHITGLIPARNKPIVGENVFLHESGIHQDGVLKHRETYEIMKPSDIGRSSETLVLGRHSGKHALRKKLESYGIKLDDETFQKVFEKFTELADRKKEVYDDDLFSIVSEVLKEPLNGYRLVHFHVHTGNTLLPTAAVVLQVGNEKKEAAETGNGPVDAIFKAIDKALGLQPKLEEYIIQAVGTGKNAQGEVKLTLKIDGELYSGRGVSTDIVEASAIAYINAINKYLIAKGLLRKNGGVE
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: ASNA_YERPY
Sequence: MKKQFIQKQQQISFVKSFFSRQLEQQLGLIEVQAPILSRVGDGTQDNLSGSEKAVQVKVKSLPDSTFEVVHSLAKWKRKTLGRFDFGADQGVYTHMKALRPDEDRLSAIHSVYVDQWDWERVMGDGERNLAYLKSTVNKIYAAIKETEAAISAEFGVKPFLPDHIQFIHSESLRARFPDLDAKGRERAIAKELGAVFLIGIGGKLADGQSHDVRAPDYDDWTSPSAEGFSGLNGDIIVWNPILEDAFEISSMGIRVDAEALKRQLALTGDEDRLELEWHQSLLRGEMPQTIGGGIGQSRLVMLLLQKQHIGQVQCGVWGPEISEKVDGLL
What are the official names of this protein?
Aspartate--ammonia ligase, Asparagine synthetase A.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: METK_PELPB
Sequence: MSQTRYFFTSESVSEGHPDKVADQISDAVLDDFLRQDSSSRVACETFVTTGQVIVGGEVTTKGIVDIQTIARKVVTEIGYTKSEYMFEANSCGVLSALHSQSPDINRGVDRKEEIADEFDRVGAGDQGMMFGYACTETPVLMPAAIQFAQHLMKKLAEIRKEGKIMTYLRPDAKSQVTLEYENEVVKRVDAVVVSTQHDPEPEGVSEAAWQEVIKNDIIENVIKVVIPADLIDENTKFHINPTGRFVIGGPHGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAARHVAKNIVAAGLADKCTVQVSYAIGVARPVSIYINTHDTAKHGLNDAQIQEKAELIFDLRPAAIIKRFSLNKPEGWCYQQTAAYGHFGRDIFPWEKTEKVGELKSALNLA
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATB_BACC7
Sequence: MNLETIIGLEVHVELKTNSKIFSASPTEFGAEPNTQTSVIDLGYPGVLPTLNKEAVNFAMKAAMALNCEIATETKFDRKNYFYPDNPKAYQISQFDKPIGENGWIEIEVDGKKKRIGITRLHLEEDAGKSTHTADGSLVDYNRQGMPLIEIVSEPDMRTPEEAYAYLEKLKSIIQYTGVSDCKMEEGSLRCDANISLRPVGQEKFGTKAELKNLNSFTYVQKGLEFEQARQEKELLSGGIIQQETRRYDEATKKTILMRVKEGSDDYRYFPEPDLVELYIDDEWKEAVRASIPELPDARKARYVAELGLPAYDAHVLTLTKEMSDFFEATVADGADAKLTSNWLMGEVLAYLNKQQKELKDVALTPAGLSKMVQLIEKGTISSKIAKKVFNELIEKGGDPEEIVKAKGLVQISDEGTLRKVVTEILDNNEQSIEDFKNGKDRAIGFLVGQIMKATKGQANPPLVNKILLEEINKR
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: MURQ_STAAC
Sequence: MMENSTTEARNEATMHLDEMTVEEALITMNKEDQQVPLAVRKAIPQLTKVIKKTIAQYKKGGRLIYIGAGTSGRLGVLDAAECVPTFNTDPHEIIGIIAGGQHAMTMAVEGAEDHKKLAEEDLKNIDLTSKDVVIGIAASGKTPYVIGGLTFANTIGATTVSISCNEHAVISEIAQYPVEVKVGPEVLTGSTRLKSGTAQKLILNMISTITMVGVGKVYDNLMIDVKATNQKLIDRSVRIIQEICAITYDEAMALYQVSEHDVKVATVMGMCGISKEEATRRLLNNGDIVKRAIRDRQP
What is the function of this protein?
Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.
What are the official names of this protein?
N-acetylmuramic acid 6-phosphate etherase, MurNAc-6-P etherase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase.
What is the protein family that this protein belongs to?
Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
Protein: AIM14_KLULA
Sequence: MDASSLVKRGSSTHYANLPYGYYVLGVIVFYTIFLIVMRWLIPSRYTKVSPWKNKLLQSIRTASPCFHMPLLLLLVFVPFIHKYSLVAYISLYLKRLGRLSYVLVILNVLLTLRPANPILGYHYLDLIPLHKWLSRFVTVIGIIHGIGFIVKWSLDPKVSMISKATKLFNFIGVIAFVPLFILMFASVRIWRRYSYRSFYVIHQLGQWAMVFLVPIHARPRVTVPYFFILLALYIWRGISYIYYSTTVNVTQRVKDDTSLTYVKLDRSAIRDWLPGSHLRLSKYKKKNPLYWLMPTQPYTIASLPDESQIDLIIRENLTPYVVVGEYTVVDVYSTVPPSLLYDSQRVAIVVGGSGISFGLSIFKYLQTRNLDYLKFIWLIREREDMHILNHCNFETNDLEVYVTRSLPPDDTQTKSMNANGSSEFDDIDFELETMDESGALLTNDSKSPSLVHFGRRLDWQVDLAQFIESHALQNSWLVCCGPESLLTDGERYAKQNYCNFVKEFYDI
What is the function of this protein?
Probable cell surface metalloreductase.  May be involved in iron or copper homeostasis (By similarity).
What are the official names of this protein?
Probable metalloreductase AIM14.
What is the protein family that this protein belongs to?
Belongs to the ferric reductase (FRE) family. AIM14 subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: METXS_AROAE
Sequence: MIQPQSVGAVVPQRAHFAEPLPLRSGDALPEYELLYETYGELNAARSNAVLVCHALSGSHHVAGHYADDPGNIGWWDNLVGPGKPLDTRKFFVIGVNNLGGCHGTTGPASINPASGKPWGADFPFVTVEDWVAAQARLADRLGIERFAAVVGGSLGGMQALSWTLQYPERIGHAVLVASAPRLTAQNIAFNEVARQAILSDPDFHGGHYYEHGVVPARGLKLARMLGHITYLSDDAMADKFGRTLRHGKAVYSYDVEFEIESYLRYQGDKFAGFFDANTYLLTTKALDYFDPAFEHGGILRAALARASADFLVVSFSTDWRFSPARSREIVYSLLHNRRNVSYAEIESDAGHDSFLLDDAHYHELLAAYFDRIEV
What is the function of this protein?
Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
What are the official names of this protein?
Homoserine O-succinyltransferase, HST, Homoserine transsuccinylase, HTS.
What is the protein family that this protein belongs to?
Belongs to the AB hydrolase superfamily. MetX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUOB_RICAE
Sequence: MKNNFYQEDELLSNELSNRGFLLTKVDDVIGWARANSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMTEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLMQLQKKIKRTTGFKYDARQTH
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B, NADH dehydrogenase I subunit B, NDH-1 subunit B.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: VSP1_CROAT
Sequence: MVLIRVLANLLILQLSYAQKSSEPIIGGDECNRNEHRFLALVSSDGNQCGGTLINEEWVLTAAHCEGNKMKIHLGVHSKKVPNKDKQTRVAKEKFFCVSSKNYTFWDKDIMLIRLDRPVSNSEHIAPLSLPSSPPSVGSVCRIMGWGTISPTKVILPDVPHCVNINLLNYSVCRAAYPEYGLPATSRTLCAGILEGGKDTCVGDSGGPLICNGQFQGIASWGSPNCGYVREPALYTKVFDHLDWIQSIIAGNTDATCPFVNF
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease catroxase-1, SVSP, Catroxase I.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: ATPF_ARTS2
Sequence: MNQTIISAATEGTNPLVPNPWEMGVVLAGFAVLFYIVVKFVVPMFEKTFAERAEAIEGGIAKAEKAQAEASAALEEYKQQLTDARAEANRIREEARAEGAQILADLKEKAAAESARITAHAHAQIESERQAAVVSLRAEVGTLATTLASRIVGESLSDDARAARVVDRFLADLENQNAGAAK
What is the function of this protein?
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
What are the official names of this protein?
ATP synthase subunit b, ATP synthase F(0) sector subunit b, ATPase subunit I, F-type ATPase subunit b, F-ATPase subunit b.
What is the protein family that this protein belongs to?
Belongs to the ATPase B chain family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: PECM_DICD3
Sequence: MKLKDFAFYAPCVWGTTYFVTTQFLPADKPLLAALIRALPAGIILILGKNLPPVGWLWRLFVLGALNIGVFFVMLFFAAYRLPGGVVALVGSLQPLIVILLSFLLLTQPVLKKQMVAAVAGGIGIVLLISLPKAPLNPAGLVASALATMSMASGLVLTKKWGRPAGMTMLTFTGWQLFCGGLVILPVQMLTEPLPDLVTLTNLAGYLYLAIPGSLLAYFMWFSGLEANSPVIMSLLGFLSPLVALLLGFLFLQQGLSGAQLVGVVFIFSALIIVQDISLFSRRKKVKPLEQSDCVIK
What is the function of this protein?
Involved in pectinase, cellulase, and blue pigment regulation.
What are the official names of this protein?
Protein PecM.
What is the protein family that this protein belongs to?
Belongs to the EamA transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NECA1_MOUSE
Sequence: MEDSRETSPSSNNSSEELSSTLQLSKGMSIFLDILRRADKNDDGKLSFEEFKAYFADGVLSGEELHELFHTIDTHNTNNLDTEELCEYFSQHLGEYENVLAALEDLNLSILKAMGKTKKDYQEASNLEQFVTRFLLKETLNQLQSLQNSLECAMETTEEQTRQERQGPSKPEVLSIQWPGKRSSRRVQRHNSFSPNSPQFNVSSPALLEEDNQWMTQINRLQKLIDRLEKKDLKLEPLEEEIIEENTKPHIMLVQRQMSVTEEDLEEFQLALKHYVESASAQSGCLRISIQKLSNESRYMIYEFWENSSVWNRHLQTNYSKTFQRSNVDFLETPELTSTMLVPASWWILNNN
What are the official names of this protein?
N-terminal EF-hand calcium-binding protein 1, EF-hand calcium-binding protein 1.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O52E5_HUMAN
Sequence: MLHTNNTQFHPSTFLVVGVPGLEDVHVWIGFPFFAVYLTALLGNIIILFVIQTEQSLHQPMFYFLAMLAGTDLGLSTATIPKMLGIFWFNLGEIAFGACITQMYTIHICTGLESVVLTVTGIDRYIAICNPLRYSMILTNKVIAILGIVIIVRTLVFVTPFTFLILRLPFCGVRIIPHTYCEHMGLAKLACASINVIYGLIAFSVGYIDISVIGFSYVQILRAVFHLPAWDARPKALSTCGSHVCVMLAFYLPALFSFMTHRFGHNIPHYIHILLANLYVVFPPALNSVIYGVKTKQIREQVLRILNPKSFWHFDPKRIFHNNSVRQ
What is the function of this protein?
Odorant receptor.
What are the official names of this protein?
Olfactory receptor 52E5.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ISA2_SCHPO
Sequence: MLMKSRVNLLFKGPFFFRERCFQTLLNPVIAIRQLSHGSLRNSRSCRIDAKSNTLTKEIFPKINNEFKIKNRFYSSKLANDQFTLQEQCDEKGIPFILYVKDSAKKQLEKIAERKPEENSVLRVTVDGGGCHGYQVSFRMDNKIGNADTVFVRGKARVVADNISLPLISGSEIEYTNELIGSSFQLLNNPRAKTSCGCNVSFDVE
What is the function of this protein?
Involved in the assembly of mitochondrial and cytoplasmic iron-sulfur proteins.  Probably involved in the binding of an intermediate of Fe/S cluster assembly (By similarity).
What are the official names of this protein?
Iron-sulfur assembly protein 2.
What is the protein family that this protein belongs to?
Belongs to the HesB/IscA family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL18_VIBA3
Sequence: MDKKASRIRRATRARRKIAELGATRLVVHRTPRHVYAQVISANGSEVIAAASTVEKAIREQVKNTGNVDAAKAVGKAVAERALEKGVASVAFDRSGFQYHGRVAALAESAREAGLKF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: MNMA_BORGP
Sequence: MKIAVLLSGGVDSSIALYKVINKGYTNIKCYYLKIWLEDELSYIGNCPWQEDLNYVEAVCNKFNIPYEIINFQKEYYNKVVIYTIEELKNGNTPSPDIFCNQRIKFGAFFEKINEQYDLVVTGHYARIQIKEKKFFLKQAKDKIKDQSYFLSHLSQEQMSKLYFPLGTLFKSEVRQIAKSINLPNKDRKDSQGICFLGKIKYNEFIKYHLGEKKGNIVEKETGKIIGIHNGYWFFTVGQRRGIKLSNGPWFVIEKDLEKNIIYISHNENYLKQAKRKFLVHEIHWINGMPSDFENFKIKIRHGEKKYSCKLRLITNNLIEIFLNKKDHGISPGQFAIFYKNTECLGGAKIFKIIE
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.