PharMolix/UniProtQA huggingface dataset:
Protein: ISPF_PSEA6
Sequence: MNLRIGHGYDVHKFGDSGPITICGVKIDYEQGLLAHSDGDVALHALCDALLGALALGDIGGHFPDTDAQFKGADSRALLRHVMTLVNEHGYEIGNLDLTIVAQAPKMAPHIQAMRENIRQDVNAQLNQVNVKATTTEKLGFAGRKEGIACYAVVLLNKSIAA
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: H31_CHLRE
Sequence: MARTKQTARKSTGGKAPRKQLATKAARKTPATGGVKKPHRYRPGTVALREIRKYQKSTELVIRKLPFQRLVREIAQDFKTDLRFQSQAVLALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H3 type 1.
What is the protein family that this protein belongs to?
Belongs to the histone H3 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: GSA2_BACAH
Sequence: MKKFDKSIAAFEEAQDLMPGGVNSPVRAFKSVGMNPLFMERGKGSKVYDIDGNEYIDYVLSWGPLIHGHANDRVVEALKAVAERGTSFGAPTEIENKLAKLVIERVPSIEIVRMVNSGTEATMSALRLARGYTGRNKILKFIGCYHGHGDSLLIKAGSGVATLGLPDSPGVPEGVAKNTITVAYNDLESVKYAFEQFGDDIACVIVEPVAGNMGVVPPQPGFLEGLREVTEQNGALLIFDEVMTGFRVAYNCGQGYYGVTPDLTCLGKVIGGGLPVGAYGGKAEIMRQVAPSGPIYQAGTLSGNPLAMAAGYETLVQLTPESYVEFERKAEMLEAGLRKAAEKHGIPHHINRAGSMIGIFFTDEPVINYDAAKSSNLQFFAAYYREMVEQGVFLPPSQFEGLFLSTAHSDADIEATIAAAEIAMSKLKA
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase 2, GSA 2, Glutamate-1-semialdehyde aminotransferase 2, GSA-AT 2.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACYP_RHIEC
Sequence: MSDHNEAVRVRISGRVQGVGFRMWTRDEALRLGVTGWVRNEADGSVSALIAGADSAISAMIERLRRGPAGASVSGVETEVAQLENMPRDFRITG
What are the official names of this protein?
Acylphosphatase, Acylphosphate phosphohydrolase.
What is the protein family that this protein belongs to?
Belongs to the acylphosphatase family.
Protein: RUBR4_RHOER
Sequence: MNDYKLYQCAQCGFEYDEAVGWPEDGIEPGTRWDDIPEDWSCPDCGAAKSDFFMVEVERR
What is the function of this protein?
Involved in the hydrocarbon hydroxylating system, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase.
What are the official names of this protein?
Rubredoxin 4.
What is the protein family that this protein belongs to?
Belongs to the rubredoxin family.
Protein: PALY_MEDSA
Sequence: METISAAITKNNANESFCLIHAKNNNNMKVNEADPLNWGVAAEAMKGSHLDEVKRMVAEYRKPVVRLGGETLTISQVAAIAAHDHGVQVDLSESARDGVKASSEWVMESMNKGTDSYGVTTGFGATSHSRTKQGGALQKELIRFLNAGIFGNGTESNHTLPKTATRAAMLVRINTLLQGYSGIDFEILEAITKPLNKTVTPCLPLRGTITASGDLVPLSYIAGLLTGRPNSKAHGPSGEVLNAKEAFNLAGINAEFFELQPKEGLALVNGTAVGSGLASIVLFEANILAVLSEVLSAIFAEVMQGKPEFTDHLTHKLKHHPGQIEAAAIMEHILDGSSYVKAAKKLHEIDPLQKPKQDRYALRTSPQWLGPLVEVIRFSTKSIEREINSVNDNPLIDVSRNKALHGGNFQGTPIGVSMDNTRLALASIGKLMFAQFSELVNDFYNNGLPSNLSASRNPSLDYGFKGAEIAMASYCSELQYLANPVTTHVQSAEQHNQDVNSLGLISARKTNEAIEILQLMSSTFLIALCQAIDLRHLEENLKNSVKNTVSQVAKKTLTMGVNGELHPSRFCEKDLLKVVDREHVFAYIDDPCSATYPLSQKLRQVLVDHALVNGESEKNFNTSIFQKIATFEEELKTLLPKEVESARTAYESGNPTIPNKINGCRSYPLYKFVREELGTGLLTGENVISPGEECDKLFSAMCQGKIIDPLLECLGEWNGAPLPIC
What is the function of this protein?
This is a key enzyme of plant metabolism catalyzing the first reaction in the biosynthesis from L-phenylalanine of a wide variety of natural products based on the phenylpropane skeleton.
What are the official names of this protein?
Phenylalanine ammonia-lyase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LUTC_BACCQ
Sequence: MTGLIQNRESFLENIAKELGRARKTDGVKRPVWKNNVNKETLKNYSQEELLEVFKNQCTNIHTTVVETTNDRLREDIQKVIVENGGGPIMLSADERFDSYGLTSLFKEELPKQNVEVNVWDPEKKEENMRIAERANIGIAFSDYTLAESGTIVVQSHKGQGRSLHFLPTVYLAIIPRETLVPRITQAVEDMNKRVENGETVASCINFITGPSNSADIEMNLVVGVHGPLKAVYFIV
What is the function of this protein?
Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source.
What are the official names of this protein?
Lactate utilization protein C.
What is the protein family that this protein belongs to?
Belongs to the LutC/YkgG family.
Protein: NR4A2_XENTR
Sequence: MPCVQAQYGSSPQGASPASQSYTYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSFSTFMDNYNTSYDVKPPCLYQMPLSGQQSSVKVEDIQMHGYQQHGHLPPQSEEMMSHSGSVYYKPSSPPTSSTPGFPVQHSPMWDNHGSLHSFNQNYVATRGGHVPRLSLFSFKQSPPGTPVSSCQMRFDGHHVSMNPETSGAHHVIDGQTFAVPNPIRKQASMGFPGLQLGHASQLIDSQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQKCLVVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAVSSLDYSRFQANPEYQMNGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFSELHKQDQDLLFESAFLELFVLRLAYRSNPAEGKLIFCNGVVLNRLQCVRGFGEWIDSIVDFSSNLHSMNIDISAFSCIAALAVITERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
What is the function of this protein?
Transcriptional regulator which may play a role in the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons.
What are the official names of this protein?
Nuclear receptor subfamily 4 group A member 2.
What is the protein family that this protein belongs to?
Belongs to the nuclear hormone receptor family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RTC4_ZYGRC
Sequence: MGIEVGKRRLVYTTSRNNDRNLDFLKRRRIEDSSSSSDHEDNQRGSLSSSSSSEEDSDRDDSHVSLRQSVDDRDLEITKKREEILDTSEIKPIERQKKSYDDEQGDVDQICKWFMDRYKFPKILYASELLEKATPLLPIVRDMYRGLVDSHYKFEANEMRQSSQRAILSVQEFRNMDLTKFTAGYYGMKRQFQIGEVILQKYKSFLLRRQGDTMKWWGVSDFAHYVLAPEVLVSLCIKEMQLSDDVYDKNARERAYDIFVNTVKFGTLVADQSPLEPWEVTP
What is the function of this protein?
May be involved in a process influencing telomere capping.
What are the official names of this protein?
Restriction of telomere capping protein 4.
What is the protein family that this protein belongs to?
Belongs to the RTC4 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: MUKB_ECO55
Sequence: MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADCAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRAPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS
What is the function of this protein?
Plays a central role in chromosome condensation, segregation and cell cycle progression.  Functions as a homodimer, which is essential for chromosome partition.  Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes.  May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
What are the official names of this protein?
Chromosome partition protein MukB, Structural maintenance of chromosome-related protein.
What is the protein family that this protein belongs to?
Belongs to the SMC family. MukB subfamily.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: K1B21_MOUSE
Sequence: MRFLILFLALSLGEIDAAPPVQSRIVGGFNCEKNSQPWHVAVFRYNKYICGGVLLNPNWVLTAAHCYGNQYNVWLGKNKLFQHESSAQHRLVSKSFPHPDYNMSLMNDHTPHPEDDYSNDLMLLRLSKPADITDAVKPIDLPTEEPKLGSTCLASGWGSITPTKWQIPNDLQCGFIKPLPNENCAKAYIHKVTDVMLCAGEMGGGKDTCAGDSGGPLICDGVLQGITSWGSIPCAKPNAPAIYTKLIKFTSWIKDTMAKNP
What is the function of this protein?
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.  Displays trypsin-like substrate specificity and shows activity towards casein, gelatin, fibronectin and IGFBP3.
What are the official names of this protein?
Kallikrein 1-related peptidase b21, Glandular kallikrein K21, mGK-21, Tissue kallikrein 21.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Kallikrein subfamily.
Protein: TIG_THEFY
Sequence: MKTAVEELSPTRVKLTIEVPFEELDHAFDVTYKSLAKQVRIKGFRPGKAPAKLIDRYVGRGAVLTQAVNHAVPELYSEAVSKEEVPVLGPPEVEITRLEDGKELAFTAEVDVRPKFEVTDYEGIEVTVDDAEVTEEQVNERLEALRQRFATLIGVDRPAEQGDHVSIDLSASVDGKKLEDAQASGVSYEIGAGTLLQGLDEAIIGLSAGESATFTTTLVGGEHKGREADVTVTVHSVKLKELPELDDEFARLASEFDTIEELRASEAERLGELLRAQQLRQARDRVLEKLVDSIDIPLPESVIKQEADRRRELLDRQLSQSGLSKEAYLEAQEKTEEEFEAELTENATRAVKTGFVLDQLASQENLTASNEELTQYVVEQAQSMGISPDQLFQSLMQANQLQLVYVEVLRAKALDLVVSKAKITDESGNTIEPPTPVHTETITVASGDEETEESAAEQGETEK
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: S5A2_MOUSE
Sequence: MPIVCHQVPVLAGSATLATMGTLILCFGKPASYGKHSESVSSGVPLLPARIAWFLQELPSFVVSVGMLAWQPRSLFGPPGNVLLGLFSAHYFHRTFIYSLLTRGRPLSAVIFLKATAFCIGNGLLQAYYLVYCAEYPEEWYTDMRFSVGVFFFILGMGINIHSDCMLRQLRKPGEVIYRIPQGGLFTYVSGANFLGEIIEWMGYALATWSVPAFAFAFFTLCFLGMQAFYHHRFYLKMFKDYPKSRKALIPFIF
What is the function of this protein?
Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids.  It plays a central role in sexual differentiation and androgen physiology.
What are the official names of this protein?
3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, SR type 2, Steroid 5-alpha-reductase 2, S5AR 2.
What is the protein family that this protein belongs to?
Belongs to the steroid 5-alpha reductase family.
What are the subcellular locations of this protein?
Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: GATM_MOUSE
Sequence: MLRVRCLRGGSRGAEAVHYIGSRLGGSLTGWVQRTFQSTQAATASSRNSCAAEDKATHPLPKDCPVSSYNEWDPLEEVIVGRAENACVPPFTVEVKANTYEKYWPFYQKNGGLYFPKDHLKKAVAEVEEMCNILSMEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILMVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYDQNYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGLVLSNPDRPCHQIDLFKKAGWTIVTPPTPVIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGISTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYFD
What is the function of this protein?
Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.  Creatine plays a vital role in energy metabolism in muscle tissues.  May play a role in embryonic and central nervous system development.
What are the official names of this protein?
Glycine amidinotransferase, mitochondrial, L-arginine:glycine amidinotransferase, Transamidinase.
What is the protein family that this protein belongs to?
Belongs to the amidinotransferase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane.
Protein: UNAG_ANGJA
Sequence: MVEKFVGTWKIADSHNFGEYLKAIGAPKELSDGGDATTPTLYISQKDGDKMTVKIENGPPTFLDTQVKFKLGEEFDEFPSDRRKGVKSVVNLVGEKLVYVQKWDGKETTYVREIKDGKLVVTLTMGDVVAVRSYRRATE
What is the function of this protein?
Beta-barrel protein that binds unconjugated bilirubin with high affinity.  Excitation of the bilirubin-bound protein gives rise to green fluorescence, both under normoxia and hypoxia.  The apoprotein is not fluorescent.  Does not emit fluorescence in the presence of ditauro-bilirubin, urobilin or biliverdin.
What are the official names of this protein?
Bilirubin-inducible fluorescent protein UnaG, Unagi green fluorescent protein, UnaG.
What is the protein family that this protein belongs to?
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARG7_VIGRR
Sequence: MGFRLPGIRKTLSARNEASSKVLDAPKGYLAVYVGENMKRFVIPVSHLNQPLFQDLLSQAEEEFGYDHPMGGLTIPCSEDLFQHITSCLSAQ
What are the official names of this protein?
Indole-3-acetic acid-induced protein ARG7.
What is the protein family that this protein belongs to?
Belongs to the ARG7 family.
Protein: EFG2_HAHCH
Sequence: MKLQKLRNIGIIAHVDAGKTTLTERLLHFTGALHSMGEVHHGGTVTDHMVQERQRGITIASAAVTVGWRDHRINIIDTPGHIDFNIEVNRSLRVLDGAVVVFDSVAGVEPQSETNWRLADQYGVPRICLVNKMDRIGADYLRVVAMIRERLGAQPLVVHLPVFVEETYVGLIDLTTMSLHRWNADDGWKYSSEEITPEYQEQAAQYRAQLEETLVELDDELLEGWFNGATLQADDLKRLIRQGVVSGAFVPVLCASAFKNKGVQMVLDAVVDYLPSPQEVKGMETVDGAQIVDADVDGAFAALAFKVVNDKHGALTYVRVYRGTLQSGSRVLNTNVGQYERIGRIYEMHADRKVARDRIGAGDIVALVGMKHTQTGDTLCAPEAPLVLERINAPEPVMDIVIEPKSRQDQDRLGEALRAIVGEDPSLRLSTGAAGETLVSGMGELHLEIVVDRLQTDFDIAVTVGRPQVAYRETITQSAAVDYVYKKQKGGPGQFAEVRMRFEPIAGDGIEFESQIVGAAIPREYIPAVEDGVRQAARSGVLGGYPCGGFKAVLLDGAYHAQDSSQLAFSVAGREAFKEAMAQATPRLLEPVMAVEIVTPRDHVGDCIGDLMRRRGSILNQLDRGDACVINAEAPLAEMFGYIGDLRTMTAGRASFSMTFSHYAETPQGVADAVLNAD
What is the function of this protein?
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation.  During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively.  Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
What are the official names of this protein?
Elongation factor G 2, EF-G 2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GL119_ARATH
Sequence: MKVSMSLILITLSALVTIAKAYDPSPLQDFCVAIDDPKNGVFVNGKFCKDPKQAKAEDFFSSGLNQAGITNNKVQSNVTTVNVDQIPGLNTLGISLVRIDYAPYGQNPPHTHPRATEILVLVEGTLYVGFVSSNQDNNRLFAKVLNPGDVFVFPIGMIHFQVNIGKTPAVAFAGLSSQNAGVITIADIVFGSTPPINPDILAQAFQLDVNVVKDLEAKFKN
What is the function of this protein?
May play a role in plant defense.  Probably has no oxalate oxidase activity even if the active site is conserved.
What are the official names of this protein?
Germin-like protein subfamily 1 member 19.
What is the protein family that this protein belongs to?
Belongs to the germin family.
What are the subcellular locations of this protein?
Secreted, extracellular space, apoplast.
Protein: MSCL_PSEF5
Sequence: MGVLSEFKAFAVKGNVVDMAVGIIIGAAFGKIVSSFVGDVVMPPIGLLIGGVNFGDLAVTLKAAAGDTPAVVLAYGKFIQSIIDFVIIAFAIFMGVKVINRLKREEAVAPTLPPVPTKEEELLGEIRDLLKAQNNKP
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: EIF3C_CRYNB
Sequence: MSFFAKLQGSDSESSSGSESEESILSGSEGERQDKKLAAQKKQQKSKASMFLNSEESESEEESSDEDEEEMSDSDDERQAVANKFLNDAASSDEESEEEDKIIVLSAKDKRFAEMEAAIHSIQNAVKNTDWVLASSELDKLFRFIARHLVTIVASPIPAEGHIPPRFLETLVSLEADVAKTLAAEKSAPKKMAPAKAKAVNGIRQTLKKKSKEFDGVLKTYNEDPEAYTAAYEKANAAPAAPKPKKAAVTTPGEGEDDEFMTIGKGGKTLNLTADGVFKTLREIFEARGRKNTDRAETIKILTKLLEVSETTYQKIRVLLALVPARLDYSQHLVSIPQESWVTALQEFDQLISILIAEPDYLVQETVGEYDDLVERTPEVVDGKKQKVLIAGSLISLLESLDSELTKTLQHTDAHEKGDEYIDRLKHEAPLYTTIVKAQTLFEREQLSDNIARTVIRRLEHIYAKPDIIIEHFESKATQAAAGLKSEITPFDVKRDASGVIHDLAVFIYQSDAPVLRARAILYHIFNQALHGRYHQARDLLLMSHLQDTISHADVTTQILYNRAVMQVGLAAFRLGFIPECQTILSEMFSTLRQKELLAQSVQRYNIQLSPEQELLEKRRLLPFHMHLNVELLEAAYLTSCMLVEIPLLASVDTEEQRRRVTSKTFKRLLDMADRQAFMGPPENTRDHIIKASQALQAGEWEKARDLIVSIKVWSLLDNAAEVKDILAKKIQEEGLRTSLFTYAAYYDSLSLSHLASTFNLPVGRITSIISRMIYTDELAASLDQIDGVVIFHRVEQSEVQRLAQQLAERTASMLEQNEKTLDVKLGNQGQGQDRDTRAVGGEGGRQQGERRGGRGTYRGRGGRGGRGGFNQGLGTTMGRRVTAQ
What is the function of this protein?
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.  The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
What are the official names of this protein?
Eukaryotic translation initiation factor 3 subunit C, eIF3c, Eukaryotic translation initiation factor 3 93 kDa subunit homolog, eIF3 p93, Translation initiation factor eIF3, p93 subunit homolog.
What is the protein family that this protein belongs to?
Belongs to the eIF-3 subunit C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NU2M_AILFU
Sequence: MKPPIFIIIMTTVISGTMMVLISSHWLLIWIGFEMNMLAIIPILMKKFNPRAMEASTKYFLTQATASMILMLGIIINLLYSGQWTMLHTPNPMASNMMTIALTMKLGLSPFHFWVPEVTQGISLSSGMILLTWQKIAPLSVLYQMAPSINPNLLMSMAIMSMLVAGWGGLNQTQLRKILAYSSIGHMGWMTSITVYNPTLMHLNLVMYIMMTLGTFMLFMYNSSLTTLSLSYSWNKFPLTTLLILMLMLSLGGLPPLSGFIPKWMIIQELTKNNMIIIPTFMAIAALLSLYFYMRLTYTTALTMFPSMNNMKMKWQFENTKKITLLPPLIIMSTMLLPMTPMMLILY
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CYB_EMYBL
Sequence: MSTNLRKTHPLAKIINSSFIDLPSPSNISAWWNFGSLLGACLILQTTTGIFLAMHYSPDISLAFSSVAHITRDVQYGWLIRNMHANGASLFFMCIYLHIGRGLYYGSYLYKETWYTGTTLLLLTMATAFVGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVQWIWGGFSVDNATLTRFFAFHFLLPFAIMGLTMVHLLFLHETGSNNPTGLNSNTDKIPFHPYFSYKDLLGLTLMLALLLTLTLFSPNLLGDPDNFTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALMLSILVLFLMPTLHTSKQRTAQFRPLTQILFWSLIANLLVLTWIGGQPVENPFITIGQMASILHFSILLILMPIAGTIENKMLT
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: CEP2_EHV1B
Sequence: MMAAASDSCLSLWEGSASSPNRQLTPEAVNCLTEALTEDVAVLRLIRSDPRVKIFMAVSVLTPRLARFAPPPPKLTHTAKCAVIMIYLTRPKALALQPKQFHMLVTFNKASVYSLVVRVKTKPFPVGTQRFRAVFQDPEFIGLPSDIPDPAAENIPTEINDRLDVSNFATPAQPPKDKYDCCVLAPGVWWSNANKAIYFLQMDVALLALCPAGWKARGLGIILGRLLNHQEGCATCRFTEHSDPLNATADSVATPESCLCWAPCLWRKAHQRELTVEGDRYLFRVLFMDAVERVRLTGLRRSPKITANLADLVVGIGPHGQQIPVNNAGWKLVALDADISRLIVCGCYALRYICPPTNSKHQPSSPDEYA
What is the function of this protein?
Plays a critical role in cytoplasmic virus egress.  Participates in the final step of tegumentation and envelope acquisition within the host cytoplasm by directly interacting with the capsid.  Upon virion binding to target cell, a signaling cascade is triggered to disrupt the interaction with the capsid, thereby preparing capsid uncoating.
What are the official names of this protein?
Cytoplasmic envelopment protein 2.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae cytoplasmic envelopment protein 2 family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus. Note=Localizes in the host nucleus up to 18 hours postinfection, but at later times localizes to punctate, cytoplasmic structures.
Protein: Y013_BORBU
Sequence: MNNSVLTKKLFLLKILTNNIEGKITENFEEIDNEIKQKIEKAKNTKIYQKNENSKEPAKLPLENQNSKNILLNNSLQEKGINDQIIIYVNKNYLNEPSRDIITKWCKSINIYNYKIIDTIESLNLEISNKNPKAILSCEEIDFFLNQPLRIHIVRGIELRFKGIPLVFTYLPTNQIKNPELKKEIWQDLKIIKGIIKYG
What are the official names of this protein?
Uncharacterized protein BB_0013.
Protein: KITH_THEMA
Sequence: MSGKLTVITGPMYSGKTTELLSFVEIYKLGKKKVAVFKPKIDSRYHSTMIVSHSGNGVEAHVIERPEEMRKYIEEDTRGVFIDEVQFFNPSLFEVVKDLLDRGIDVFCAGLDLTHKQNPFETTALLLSLADTVIKKKAVCHRCGEYNATLTLKVAGGEEEIDVGGQEKYIAVCRDCYNTLKKRV
What are the official names of this protein?
Thymidine kinase.
What is the protein family that this protein belongs to?
Belongs to the thymidine kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CUC14_CONCL
Sequence: DLITNSYTRGKPRHVTSWRNLKTRDVCDSLVEGRCIHNGCQCDRSAPHGNCCDTDGCTSLWWCPKTKWD
What are the official names of this protein?
Conotoxin Cal12.1p4.
What are the subcellular locations of this protein?
Secreted.
Protein: NRDR_PERMH
Sequence: MKCPKCGSLNDKVVDTRQSKDGTVIRRRRECLDCGYRFTTYERFEEEKIVVKKKNGTTEPFNKDKIIRGIRLASKNRPVSEKQMVEIADEIEKYLLEEGKLVVESTEIGDLVQEKLKKIDPVSYLRFKSVYNEFQDIKDFEKALKEIEEKGE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.