PharMolix/UniProtQA huggingface dataset:
Protein: EFNA1_HUMAN
Sequence: MEFLWAPLLGLCCSLAAADRHTVFWNSSNPKFRNEDYTIHVQLNDYVDIICPHYEDHSVADAAMEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEGHSYYYISKPIHQHEDRCLRLKVTVSGKITHSPQAHDNPQEKRLAADDPEVRVLHSIGHSAAPRLFPLAWTVLLLPLLLLQTP
What is the function of this protein?
Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development.  Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells.  Plays an important role in angiogenesis and tumor neovascularization.  The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly.  Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2.  Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation.  Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK.  Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.
What are the official names of this protein?
Ephrin-A1, EPH-related receptor tyrosine kinase ligand 1, LERK-1, Immediate early response protein B61, Tumor necrosis factor alpha-induced protein 4, TNF alpha-induced protein 4.
What is the protein family that this protein belongs to?
Belongs to the ephrin family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI-anchor. SUBCELLULAR LOCATION: [Ephrin-A1, secreted form]: Secreted.
Protein: RTCA_PSEF5
Sequence: MKQDVVELDGAIGGGQVLRSALSLSMLTGKTLRIHNIRARRSRPGLLRQHLTAVLAAAQVCGARSTGAELGSQVLSFEPGPIRGGDYRFAIGTAGSCTLVLQTLLPALLRAPQPSRVSISGGTHNPLAPPVDFLQQAWLPQLRRMGGRVELQLLRHGFVPAGGGELEAFIQPSELQPLHLQERGALLGSRAWALSAGLPEHVAERELRRVHDRLQLPREQLTPVLLDEEYGPGNVLLLEFAFEHLTELFCGFGQNSLRAEKVADGAIDQARDWLDSGAAVAEHLADQLLLPMALAGGGSFTTPCMTEHLQSNIRVIEAFLPVRIEARPLSEQVLQVQCHALS
What is the function of this protein?
Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA.  The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product.  The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
What are the official names of this protein?
RNA 3'-terminal phosphate cyclase, RNA cyclase, RNA-3'-phosphate cyclase.
What is the protein family that this protein belongs to?
Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MFNA_METM5
Sequence: MEEQDILNELRKYRSQDLKYEEGYILGSMCTKPHPIARKISEMFFETNLGDPGLFNGTSKLEKEVVSMLGSILHNNNAFGYIISGGTEANLTAMRAFKNISKSKDKKQNIIIPETAHFSFDKARDMMDLNVVRPPLTEYFTMDVKFIRDYVEDSKNEISGIVGIAGCTELGSIDNIYELSKIAVENDILLHVDAAFGGFVIPFLDDKYKLKGYNYDFDFSLNGVSSITIDPHKMGLAPISAGGILFRDNTFKKYLDVDAPYLTEKQQATLIGTRSGVGVASTWGIMKLLGIEGYENLVNESMEKTKHLVKKAREYGFETAIDPVMNIVALKDENKQDTCMKLREENWYVSVCRCVEALRIVVMPHLEIEHIDGFLESLSNTKKY
What is the function of this protein?
Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis.  Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis.
What are the official names of this protein?
Probable L-tyrosine/L-aspartate decarboxylase, TDC/ADC.
What is the protein family that this protein belongs to?
Belongs to the group II decarboxylase family. MfnA subfamily.
Protein: RL331_STRP6
Sequence: MRVKINLECSECGSNNYLTSKNKSSHPEKIKVPKYCPKERKVTLHVET
What are the official names of this protein?
50S ribosomal protein L33 1.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: NU4C3_SYNP2
Sequence: MAPDFPWLTAIIALPALSTLLIPLLPDKEGKTVRWYALIVGLVDFALMCFAFWQHFDPQATEFQLAESYRWLPSLGIQWSVAVDGISAPLVLLAGFVTTLAMFSAWQVNQRPRLFYALMLLLYSAQIGVFVAKDLFLFFLMWEIELIPVYLLVCIWGGKRRRYAAMKFLLYTAAASIFILVAALALSLNLPGGPNFDLGAIAQQDYPLGLQMWLYAGLLVSFGVKLAIFPLHTWLPDAHGEASSPVSMLLAGVLLKMGGYGLMRFNMELLPDAHVRFAPLLVILGVVNIVYGAFSSFGQTNMKRRLAYSSVSHMGFVLIGIASFTDLGINGAMLQMLSHGLIASVLFFLAGVTYDRTKTMVLAEVGGLGQVMPKVFAMFTVGALASLALPGMSGFVGELSVFVGLASSDTYSATFRTITVFLAAVGVILTPIYLLSMLREMFYTREMDLSCDLGQPTNVAIAGNAPVCFGNDCVLPSNAIYEDARPREIFIATCFTVLIIGVGLYPKLLMQMYDAKTQTLNTSVRQAQAIAKQPSEPIAALQAPELTMPH
What is the function of this protein?
NDH-1 shuttles electrons from NAD(P)H, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase chain 4 3, NAD(P)H dehydrogenase I, chain 4 3, NDH-1, chain 4 3.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4 family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Multi-pass membrane protein.
Protein: MSCL_BARBK
Sequence: MLKEFKQFALKGNMVDLAVGVIIGSAFGGLVNSVVNDIFMPIIGLITGGIDFSNMFIQLAGDKKATLLAAKEAGATLSYGNFITLLINFLIISWILFFLVKGMNKMTQKQEEVEKPKEMSPEGKLLTEIRDLLAAQKE
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PPIF_RAT
Sequence: MLALRCGPRLLGLLSGPRSAPLLLSTTRTCSDGGARGANSSSQNPLVYLDVGADGQPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPAFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGKTSKKIVITDCGQLS
What is the function of this protein?
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding (By similarity).  Involved in regulation of the mitochondrial permeability transition pore (mPTP) (PubMed:8567677, PubMed:9309684, PubMed:9820802).  It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated (PubMed:8567677, PubMed:9309684, PubMed:9820802).  In cooperation with mitochondrial p53/TP53 is involved in activating oxidative stress-induced necrosis (PubMed:8567677, PubMed:9309684, PubMed:9820802).  Involved in modulation of mitochondrial membrane F(1)F(0) ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels (PubMed:8567677, PubMed:9309684, PubMed:9820802).  Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis (PubMed:19228691).
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase F, mitochondrial, PPIase F, Cyclophilin D, CyP-D, CypD, Cyclophilin F, Rotamase F.
What is the protein family that this protein belongs to?
Belongs to the cyclophilin-type PPIase family.
What are the subcellular locations of this protein?
Mitochondrion matrix.
Protein: RL22_STRPJ
Sequence: MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTPNKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINKRTAHITVAVAEK
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: ARCH_ARCFU
Sequence: MKYRFIDHTADIAFEVYGSNLRELFENAALAFYDAFVDTSGIGIEREVGVECEGEDVEITLYRWLNELLYLFDTEFFAAKDVEVEVEEGDGVKASGKLRGGRFSAEMVKVEPKAITLHKFRVEKTDKGYVAFVVVDI
What is the function of this protein?
Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB.  Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation.  Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity).
What are the official names of this protein?
Protein archease.
What is the protein family that this protein belongs to?
Belongs to the archease family.
Protein: YDGU_ECOLI
Sequence: MVGRYRFEFILIILILCALITARFYLS
What are the official names of this protein?
Uncharacterized protein YdgU.
Protein: RHMD_PARP8
Sequence: MAMPSIRHVRAFVVRGGGADYHDQADGHWIDDHISTPMARYPEYRQSRQSFGINVLGTLVVEIEASDGTVGFAVTTGGEIGAFIVEKHLARFLEGQLVTDIEKMWDQMYFSTLYYGRKGVVLNTISGVDLALWDLLAKVRKEPVYQLLGGPVRDELQFYATGARPDLAKEMGFIGGKLPLQHSPAEGEEGLRKNIDKLAEMRGRVGGDFWLMYDCWMSLDVTYATKLAKAAHEHGLKWIEEALPPDDYWGYAELRRNVPRGMMVSTGEHEATRWGFRMLLEMGCCDLIQPDVGWCGGITELVKISALADAHNVLVVPHGSSVYSYHFVVTRHNSPFAEFLMMAPKADQVVPMFTPLLLDEPVPVNGRMRVPDTPGFGVRLNPECKLERPYQH
What is the function of this protein?
Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR).
What are the official names of this protein?
L-rhamnonate dehydratase, RhamD.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. RhamD subfamily.
Protein: RHAB_SALTY
Sequence: MTFRHCVAVDLGASSGRVMLARYDSKHRTLTLREIHRFVNCLQKTDGFDTWDIDSLEKDIRLGLKKVCNEGILIDSIGIDTWGVDYVLLDKQGQRVGLPVSYRDNRTTGIMPQALVQIGKSEIYRRSGIQFLPFNTIYQLRALTKQQPELTAQVAHALLMPDYFSYRLTGEMNWEYTNATTTQLVNINTDDWDDTLLAWTGAKKSWFGRPSHPGNVIGDWICPQGNRIPVVAVASHDTASAVIASPLANKHSAYLSSGTWSLMGFESKMPYTTDEALAANITNEGGAEGRYRVLKNIMGLWLLQRVLKERRITDLPALIAQTEALPACRFLINPNDDRFINPDDMRAEIQAACRETDQPVPVSDAELARCIFDSLALLYADILHEQANLRGEKFTQLHIVGGGCQNSLLNQLCADACGIRVMAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSANYDLTTYIPNPDSEIARHVAQFQPKRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: IOLG_PSEF5
Sequence: MSLQLGVIGTGAIGQDHIRRCSQTLQGCRVVAVTDIDPQQAARVLAGLTLEAEVYPDGHALIQAPEVQALLVTSWGPSHEEFVLAAIAAGKPVFCEKPLAVTAAGCRRIVEAEIAQGRRLVQVGFMRPYDAGYQALKAVVDSGRIGEPLMLHCAHRNPRVGENYKTDMAITDTLIHELDVLRWLLADDYVSVQVLFPRKTGKAHAQLRDPQIVLLETARGTRIDVEIFVNCQYGYDIQCEVVGESGIARLPEPPQVQLRSAASLSSAILMDWKERFIAAYDVELQAFVDGVRAGRVGGPSAWDGLAAAVAADACIEAQQSGAIVPISLPQRPALYA
What is the function of this protein?
Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose).
What are the official names of this protein?
Inositol 2-dehydrogenase, Myo-inositol 2-dehydrogenase, MI 2-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the Gfo/Idh/MocA family.
Protein: LGT_CAMJR
Sequence: MEFWQHIYSNFNVIAFSIFGLKVHWYGIMYVIALLLALLLAKFFVRKFQLDINEKHLDSYFIWVEIGVILGARLGYILIYDANTMYYITHPWQIFNPYINGEFVGIRGMSYHGAIIGFLIATLLFCKKYKANPWIFLDLVALSVPLAYVFGRIGNFLNQELFGRITNVPWGIYVDGVLRHPSQLYEAFLEGIVVFIIVYLARFKQSFQGELILVYAGAYSLARFICEFYREPDFGIGFVLWGMSMGQILSFIMFITALLVYICIKFKKVNI
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: T1SD_MYCPN
Sequence: MEAPKFVNNACPIPNLNLSRTEEIELDFPPLQIQQKIATILDTFTELSAELSAELSAELSAELSAELSAELSAELSAELSAELSAELSAELSAELSAELSAELSAELSAELRERKKQYAFYRDYLLNQENIRKIYGANIPFETFQVKDICEIRRGRAITKAYIRNNPGENPVYSAATTNDGELGRIKDCDFDGEYITWTTNGYAGVVFYRNGKFNASQDCGVLKVKNKKICTKFLSFLLKIEAPKFVHNLASRPKLSQKVMAEIELSFPPLEIQEKIADILFAFEKLCNDLVEGIPAEIELRKKQLDYYQNFLFNWVQEQKKNSLSTNLN
What is the function of this protein?
The specificity (S) subunit of a type I restriction enzyme; this subunit dictates DNA sequence specificity.  The M and S subunits together form a methyltransferase (MTase) that probably methylates A-2 on the top strand and A-3 on the bottom strand of the sequence 5'-GAN(7)TAY-3'.  As the bacterial DNA is methylated on this sequence and this is the only type I methylase in the genome, it is probably responsible for all of the methylation on this site in the genome.  The R subunit has multiple frameshifts and is probably not expressed in this bacteria.
What are the official names of this protein?
Type I restriction enzyme MpnII specificity subunit, S protein, Type I specificity subunit S.MpnII, S.MpnII, Type-1 restriction enzyme specificity subunit MpnII.
What is the protein family that this protein belongs to?
Belongs to the type-I restriction system S methylase family.
Protein: HSE1_PHANO
Sequence: MFRAQSNIFDDVVVKATDENLTSENWEYILDVCDKVGSSDTGAKDAVAAMIKRLAHRNANVQLYTLELANALSQNCGIQMHKELASRSFTDAMLRLANDRNTHQAVKAKILERMGEWSEMFSRDPDLGIMEGAYMKLKTQNPNLRAPSKPQKTQISDSDRQKEEEELQMALAMSIKESKGATPSAAKANAPQESNAGSSSQAAPAPQPVQPGTTAATVSRVRALFDFQPSEPGELQFKKGDIIAVLESVYKDWWKGSLRGNTGIFPLNYVEKLQDPTREELEKEAQTEAEVFAQIRNVEKLLALLSTNTQAGGGDGRDNEEITELYHSTLAIRPKLIELIGKYSQKKDDFTQLNEKFIKARRDYESLLEASMSQPPQPSYGSRPPYGYNAPPPSNYTGYPPSSPPPQQYGYGAGAPPQGSAPQYPPVGANPAFFMVPPAGEQRPQQQTPQPGPPSDPYSLPQGRVPIGGRPQSYAPQELATAHYDSPVDNRHSFAGPSQPQGAPSAPQGYEYPPSQAPPGYPPQQGAPLQGPPPGQQNPYEQISSPPTHQQPPSDPYSQPPPQVGHGYPPQQPAHAPPAPPGASSSPAPAQGYLPYRPPGQAPSAPPVGGGGDEGFYR
What is the function of this protein?
Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB).
What are the official names of this protein?
Class E vacuolar protein-sorting machinery protein HSE1.
What is the protein family that this protein belongs to?
Belongs to the STAM family.
What are the subcellular locations of this protein?
Endosome membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: KADA_SULIM
Sequence: MKIGIVTGIPGVGKTTVLSFADKILTEKGIPHKIANYGDYMLNTALKEGYVNSRDEIRKLQIEKQRELQALAARRIVEDLSLLGDEGIGLIDTHAVIRTPAGYLPGLPRHVIEVLSPKVIFLLEADPRIILERQKRDNSRARADYSDTTVINEVIQFARYSAMASAVLVGASVKVVINQEGDPSIAASDIINSLM
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase.
What is the protein family that this protein belongs to?
Belongs to the archaeal adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PFS2_GIBZE
Sequence: MAYEPRGDHGGGGGGQGQDGAFVKVRGRRPVTDYGATITHWQHDRAPGYKGGYTGEAERPSASYIVDMLPPAARVTKAADSIPIKHLHSSLNKIKHPINVVRWTPEGRRLLTASTSGEFTLWNGTGFNFETIMQAHDSAIRALEYSHSDDWLISADHDGAVKYWQPNFNNVQSINAHTDPIRDLAFSPSDSKFVTASDDSTLKIFDFALGQMESKLEGHGWDAKSVDWHPTKGLLVSGSKDHLVKLWDPRTSRCLTTLHGHKSTITKVLFEKVRGACLATSARDQTARVFDLRMMRDICLLKGHEKDISTLTWHPVHPNLLSTGGMDGSLFHYLLDSPNPPPGQSFTVAPYDSPDPTTVPAQSVWPTHKVPYAHDYAIWSLDWHPLGHILASGSNDRITRFWSRARPGDAEVFQDRYHIGEAAAEAQGTWDRRGGRRQRQEEEQQEMEDEMDALVDQDAPKAGVPGLPGIPGLPLGGLPGLGSAVPPPPIPGVGAGGPPPPLPFPLPGLNGSLPPPPLPGLDPNNPPDPAQLLELMKKAGVPLPPPGALPPGLLPPGGIPPPPGGFGMPIPPPPMSALEAEKAENVRRRAPLPSQEDSLRHEQRQGKYTRAR
What is the function of this protein?
Required for 3'-end cleavage and polyadenylation of pre-mRNAs.  Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity).
What are the official names of this protein?
Polyadenylation factor subunit 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: APCB_SYNY4
Sequence: MQDAITAVINSADVQGKYLDGAAMDKLKNYFASGELRVRAASVISANAATIVKEAVAKSLLYSDVTRPGGNMYTTRRYAACIRDLDYYLRYATYAMLAGDASILDERVLNGLKETYNSLGVPISSTVQAIQAIKEVTASLVGADAGKEMGVYLDYICSGLS
What is the function of this protein?
Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex.  Allophycocyanin has a maximum absorption at approximately 650 nanometers.
What are the official names of this protein?
Allophycocyanin beta chain.
What is the protein family that this protein belongs to?
Belongs to the phycobiliprotein family.
What are the subcellular locations of this protein?
Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=Forms the core of the phycobilisome.
Protein: PANB_SYNAS
Sequence: MSTQSKGRKITTSVIRGMKKKGEKITMLTAYDYAMASLLDEVGVEMLLVGDSLGMVVLGYESTLPVTMNDMLHHTRAVSRGANNAMVVADLPFMSYQCSVEEAVRNAGRFLQEAGAHAVKLEGGREIAESVKRMTVSGIPVVGHLGLTPQSVQQFGGFKVQGKGDAAAQRIMEDAKIIEEAGAFSVVLECVPAPLAQRITDDLAIPTIGIGAGAGCDGQVLVVNDMLGIYERFTPKFVKKYANLSDNIRGAVKQYIEEVKNGTFPDQDHSFL
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RECX_PSEAE
Sequence: MAIVLDTPVAVRRAAMDLLARREHGRAELSRKLRQRGASAELIDPALDRLAEEGLLDESRYLESFIASRARSGHGPLRIREELAQRGLPRADIERALGACEVDWSAQLREVWRRKFARLPQDAREKAQQGRFLAYRGYSMESISRLLNGRSDD
What is the function of this protein?
Modulates RecA activity.
What are the official names of this protein?
Regulatory protein RecX.
What is the protein family that this protein belongs to?
Belongs to the RecX family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: THIC_HALSA
Sequence: MSTQLQHARDGTVTDAMRRVADREGRDPEVVREAVADGHAVIPANHHHDALDPMIIGRDFATKVNANIGNSDTTGDIDDELEKLHTAVHYGADTVMDLSTGENLDGIRTANIDNSPVPVGTVPIYEAVTRVEDVTDITPDLLIDVVEKQAKQGVDYMTLHAGVLAEHLPLTDDRTTGIVSRGGSILSQWMTEHGEQNPLYTHYDELCEILQAHDVTISLGDGLRPGSVADASDDAQFAELDTLGELTRRAWDHGVQAMVEGPGHVPMDQIRANVDRQQEVCDGAPFYVLGPLVTDIAPGYDHITSAIGATEAARAGAAMLCYVTPKEHLGLPDAEDVRDGMAAYRIAAHAGDVAAGKPGARDWDDALSEARYNFDWNRQFDLALDPERAQAFHDQTLPGDNYKDARFCSMCGVDFCSMRIDQDARDAGDDADDMTELTTETDLSESAAAEVNRPPTGTHDAPAAEQAPSPGDDDDD
What is the function of this protein?
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
What are the official names of this protein?
Phosphomethylpyrimidine synthase, Hydroxymethylpyrimidine phosphate synthase, HMP-P synthase, HMP-phosphate synthase, HMPP synthase, Thiamine biosynthesis protein ThiC.
What is the protein family that this protein belongs to?
Belongs to the ThiC family.
Protein: XGPT_SHIDS
Sequence: MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR
What is the function of this protein?
Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi.  To a lesser extent, also acts on hypoxanthine.
What are the official names of this protein?
Xanthine-guanine phosphoribosyltransferase, XGPRT, Xanthine phosphoribosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSTC_METJA
Sequence: MKTMEIKKLLRKIDEFKIITLPAIFVVFILFVLILGFYFFNALPAIERYGIDLFITNVWKAAEEPAKEVYGLAAPIWGSIYTATIAVLIALPLSICYAIFVNDYAPKRLKYPLIVISDIMAGLPTIIYGIWGAFILVPLLRDHIMKFLYEHFSFIPLFDYPPLSGYCYLSAGILLGIMVTPFAAAIIREAYAMIPSVYKEGLVALGATRYETTKVLIKYIRPAIISGLILAFGRALGETVAVSLVIGNSFNLTYKLFAPGYTISSLIANQFGNAVLYEYMTSVLYSAGLVLFVIGLVVNIIGIYYLKRWREHVSH
What is the function of this protein?
Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.
What are the official names of this protein?
Probable phosphate transport system permease protein PstC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYI_EHRRW
Sequence: MCIVKTLHLITHVMKEYNSQFTEGSDFSLIEEQILEFWKENNIFKKSIENRDEKRRFIFYDGPPFANGLPHYGHLLTGFIKDTVARYKTMAGFRVDRRFGWDCHGLPAEMLAEKELGVSGKLAIEKFGIEKFNNYCRNSVMKFSREWKQYIDRQSRWVDFENDYKTMNLSFMESIMWSFYQLWQKGLIYESIKIVPYSWACQTPLSNFETRIDNAYRQKTSKTVTLAFELLDAPKSLIVDNITAYKILVWTTTPWTLPCNLALAISPNIKYCGAIINKEMYIFSRAYLKNFEDHCRKNNIEYLIHNGDICYLSLEYLSYKPVFNYFIDIKNAFKVLVADFVVEDEGTGIVHMAPGFGEDDFILCKKQGIPDIDDKDTSKLLATICPIDDGGKFTERISDFVNMHVFDTNDQIISILKAKNLCFKTDQYLHNYPHCWRTDTPLIYRAMSSWYVEVTKIKNRMIDLNKDVNWIPSHIRSGQFGKWLENAKDWAISRNRFWGTPLPVWKSDNPNYPRVDVYGSIKKVFDDIKALEEDFDIPIDDLHRPYIDNLVRPNPDDPTGKSMMRRVTDVFDCWFESGSMPYAQLHYPFENKELFENYFPADFITEYVAQTRGWFYTLFVLSTALFDKPPFKNCICHGVVLDTQGQKLSKRLNNYADPMEIFKQYGSDAMRFLMLSHTVSYGGDLLLDKDGVMVRDVIRNVIKPMWNSYNFFTIYADIDKVNARVISDLDEVDNIMDKYIMCECISTIQSIFNAMEEFDQSVGNYGYNIKAACNSIVQFFEVLNNWYIRRCRSRFWSSEITKDKVNAYNTLYTVMYYMVKVSAPFLPAITEAIWQKLNFQEEESVHLSLLPNIEHITLKDEDQKNIQYMKLIINICGCVLSIRNVRNIRVRQPLNKITIYSYNNNDLFNLPVKYQNILLDEINVKSIVFKSNIEDIASFQLKLNFPELGKRIPEKMKNLISLLKSNQWKILENGQLMLGIREGEHYILEDNEYTLNLKVHSEFASTITLGPNLLGVLVLDNTLTDELIMEGIARDIVRIIQQSRKDNKFNVSDKIDVVICTQDKMVKNSVQAWYEYIVQQTLSLSLVIYENLDANNVAEYCKTTMKDRNLTLFIKKL
What is the function of this protein?
Catalyzes the attachment of isoleucine to tRNA(Ile).  As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities.  One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
What are the official names of this protein?
Isoleucine--tRNA ligase, Isoleucyl-tRNA synthetase, IleRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF859_ASFM2
Sequence: MYAGFYVAVHPWLETQSLHKVGHTGNLAARLHDGSYTTCFTDEWKYCFTLETPTKKDAQKIEAGVLYCAQFFRVKNKELLCLLPEKIKQLAEDVAKCLDISYTLCDSPTYEMNDSTIVVEPSLPSDPLISKEKLRHLVIIPVEDEDHFADDVLFFSTDETRTAIEDRLYQKEAANMGYQELQRSGRAILQMACRCGKTRVAYLILSNYLQGKVLYLVPGLSLLRQTLEKLYLYGISLKNVLLVGSDQTRIVLNHDNIEMTTNPVFIAKRIQEASSLLVIATYQSSTLLVDDFDLIISDECHRICGEWEIRPFTHVLLNFKKGHRLFLTATPRYDTPLSMKNRDLFGGVAFRYYLREGIEAGYVNDFELQMVAAPKLAHQLSNREETTKQIIVKQIIMALAYLKTNITSPKMLVFTRDIKQAKELYAELVDLGVYALIAHSTLPRQVILKTFTEFCSSKEPVILLNCRLFQEGVEVPELNAVFFAAPRHSPRDIIQSICRPLNKQVQKPHATIFLPLEVNTENVCLDKFSSIIPFADALASEDPRFYEHLLNPSEVAYPINWIGAHGSVSELLHLARHAIRYGTQGKIDRLTRSERLPWKAAFAELKRTVEICCRYPKINDGFHFGGATLRFDTWYKWVIKSYLQYKNKEPSSLEPYQVSDLESLQDWTTRGVGGPYPWEESMAFLETWLAQNKGELVAIDIHQGGWIGLDATPMERLSGVLTTVSQRDGRSYGKNKKLRPKKGFMIPPQQAEDLDRIFGKHNLKWRKDRVNGFLKEDEHGNYTGEPTCIQEAYRTFKEYVKTNPEYIEKYWPGYAKGKHKHQELPHIWESGLAPPRYKAFKDGNKQLIQRSPKKKDVKN
What are the official names of this protein?
Probable helicase A859L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus helicase A859L family.