PharMolix/UniProtQA huggingface dataset:
Protein: PTH_ACTP2
Sequence: MSQIKLIVGLANPGTKYEDTRHNAGEWLINEIARQFNVSLKEEAKFFGKVAKINAAGGEVRLLVPTTFMNLSGKAVGALANFYRIKPEEILVAHDELDLPPGVAKIKQGGGHGGHNGLKDIIASLGNSNNFYRVRIGIGHPGSKELVAGYVLGKPSPQDQEKINAAVDEAGRCVDLLLKDGITKATNRLNAFKA
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GLGB_THEFY
Sequence: MTARPAVRQPAGLPCPQPCNRYGYPMTNALLAEIDALVAGTHHNPHALLGAHPGPEGVWVRALRPLARSVHVLLANGSRVELPHLHKGVFAGVVPGAEVPDYRLVVRYDDGTELTVDDPYRHLPTLGELDIHLIQEGRHEELWRVLGAHTKRFPSVLGDTEGTAFTVWAPNARGVRVIGDFNHWDGTGHPMRSLGSCGVWELFIPGVGDGTRYKYQVLGADGVWREKADPVAFATQAPPETASVVFTSRYTWQDDEWLTQRAAADLHRKPMSIYEVHLGSWRPGLSYRELADQLVDYVRELGFTHVEFLPVAEHPFGGSWGYQVTSYYAPTARFGSPDDFRYLVDRLHQAGIGVFLDWVPAHFPKDDWALSRFDGTALYEHPDPRRGIHPDWDTLIFNYGRTEVRNFLVANALFWLEEFHIDGLRVDAVASMLYLDYSRESGQWEPNAYGGRENLDAIDFLRELNATAYRRNPGIAMIAEESTAWPGVTRSTDTGGLGFGFKWNMGWMHDTLSYLQHDPVHRQYHHNEVTFSMVYAYSENYVLPLSHDEVVHGKRSLLYKMPGNEWQRCANLRALLAYMWAHPGKQLLFMGNEIAQGDEWSHDAGVQWWLLRYPHHAGMRRLVADLNRLYRNTRALWSQDTVPEGFTWLDGGDASGNTLSFLRWGDDGSVLACLVNFSGRPHPERRVGLPYAGRWREILNTDAVLYGGSGVSQPGIIEASEETPWQGQPASALVTYPPLGVSWLVFDGT
What is the function of this protein?
Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
What are the official names of this protein?
1,4-alpha-glucan branching enzyme GlgB, 1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase, Alpha-(1->4)-glucan branching enzyme, Glycogen branching enzyme, BE.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
Protein: TEG3_GAHVM
Sequence: MFAVSAMRRRRRRILAECRTREAVYKERTLELLSQGVETDDPEFIEVFTSARNAHSDYKAQLRSNMRLEATDRKTKIIQRHIDEQLDRRLILDINRKLLNPKLQLQLDQTEEAILEKEDILAQTIDDITLNDSITNTDELDEESEALLTKWILNQKTKKRPTVAKTAIAPTAHGLQTKVSRNVFITGKDDLVQPTDLGQPSTHEVITCTSRERIIHPDGIHTEIYTTEDVSPTILDDVSDSCV
What is the function of this protein?
Contributes to the nuclear transport of the viral transcriptional activator VP16 homolog during the early phase of infection.  Therefore, participates indirectly in the regulation of the immediate-early gene expression.  Additionally, seems to be important for efficient nuclear targeting of capsids (By similarity).
What are the official names of this protein?
Tegument protein UL14 homolog.
What is the protein family that this protein belongs to?
Belongs to the alphaherpesvirinae HHV-1 UL14 protein family.
What are the subcellular locations of this protein?
Virion tegument. Host cytoplasm. Host nucleus.
Protein: PIPB2_SALTI
Sequence: MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILQHIINFFTCGGIRRRNETQYQELIETMAETLKSSMSDRGAPLPENIILDDVDGCRVEFNLPGENNEAGQVIVRVSKGDNSETREIPLASFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLTGANLTAENLCDADLSGADLEGAILFMADCDGANFKGANLSGASLGDSNLTNACLEDSIMCGATLDRANLTGANLQHTSLLGCSMVECNCSGANMDHANVSGSTLIRADMSGATLKGATIMAAIMEGAVLTRANLQKASFTATNLDGADLSEANLRNTSFKDCTLTDLRTEDATMSTSTQTLFNVFYSENI
What is the function of this protein?
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues.  Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells.  Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane.  Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery.  Required for virulence, but not for intracellular survival and replication in phagocytic cells (By similarity).
What are the official names of this protein?
Secreted effector protein PipB2, Type III effector PipB2.
What are the subcellular locations of this protein?
Secreted. Host membrane. Note=Secreted via the type III secretion system 2 (SPI-2 TTSS), and delivered into the host cell.
Protein: E41L1_MOUSE
Sequence: MTTETGPDSEVKKAQEETPQQPEAAAAVTTPVTPAGHSHPETNSNEKHLTQQDTRPAEQSLDMDDKDYSEADGLSERTTPSKAQKSPQKIAKKFKSAICRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPCSFVTHALLGSYAVQAELGDYDAEEHVGNYVSELRFAPNQTRELEERIMELHKTYRGMTPGEAEIHFLENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRSNFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPASVSENHDAGPEGDKREDDAESGGRRSEAEEGEVRTPTKIKELKPEQETTPRHKQEFLDKPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWDRERRLPSSPASPSPKGTPEKASERAGLREGSEEKVKPPRPRAPESDMGDEDQDQERDAVFLKDNHLAIERKCSSITVSSTSSLEAEVDFTVIGDYHGGAFEDFSRSLPELDRDKSDSETEGLVFAQDLKGPSSQEDESGGLEDSPDRGACSTPEMPQFESVKAETMTVSSLAIRKKIEPEAMLQSRVSAADSTQVDGGTPMVKDFMTTPPCITTETISTTMENSLKSGKGAAAMIPGPQTVATEIRSLSPIIGKDVLTSTYGATAETLSTSTTTHVTKTVKGGFSETRIEKRIIITGDEDVDQDQALALAIKEAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES
What is the function of this protein?
May function to confer stability and plasticity to neuronal membrane via multiple interactions, including the spectrin-actin-based cytoskeleton, integral membrane channels and membrane-associated guanylate kinases.
What are the official names of this protein?
Band 4.1-like protein 1, Erythrocyte membrane protein band 4.1-like 1, Neuronal protein 4.1, 4.1N.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: LARC_GEOKA
Sequence: MKILYLDCFSGISGDMMVGALVDAGVPSEKIEVELKKLSLSGYKLQWGKVVKKGISATKFDVIIQESIEGGHHHQSHHAHRHYSDIIDMIRRSELSEEVKQRAGQIFHCIAVAEAKIHGIPVENVHFHEVGAVDSIVDIVATAIALTELHIDYIISAPIPLGHGSIRCAHGVYPVPAPATLEILQGVPVVSNHLPFELTTPTGAGIVKSQVNSYGPLPSMKISAIGYGAGTRDLPDQPNVLRVVIGEETRITSSGPSLFHSKEETVYILECQLDDMPGEALGYVMDGLFQKGALDVFYTPVFMKKNRPGVLLTVLTSATHVEQCEQFMLKETTTLGIRKDIWVREVLERDVVTVATSYGNIRVKQAIHKGKVIRQMPEYEDVKEAALTHQVAFLDVYAEAAEQARRRIKGE
What is the function of this protein?
Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex).  Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor.  Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes.
What are the official names of this protein?
Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein, P2TMN nickel insertion protein, Nickel-pincer cofactor biosynthesis protein LarC.
What is the protein family that this protein belongs to?
Belongs to the LarC family.
Protein: CMOB_TOLAT
Sequence: MIDFASFYQVIAKSRLSHWLHTLPAQLNAWENSERHGNLPKWQRVLTKLEHYQSSHVNLSDRVEIGQPGEISAGETRKLENLLQHFHPWRKGPFYLFGIHIDTEWRSDWKWDRVLPHISPLKDRYVLDVGCGSGYHLWRMRGEGAELAVGIDPAALFLCQFTAVKQLGGNDPQVHFLPLGIQELPPLRAFDTVFSMGVLYHRRSPIDHIYQLKDQLRDGGELVLETLIVDGDENTVLVPDDRYAQMNNVWFLPSPAAMIKWLKKCGFQDVRMVDEDVTTTDEQRKTEWMQNDSLAQYLMPDDPTRTIEGYPAPKRAVFVATRGSED
What is the function of this protein?
Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
What are the official names of this protein?
tRNA U34 carboxymethyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
Protein: ATPB_YARLI
Sequence: MVLPRLIPRLSRSAFKVAQANNRVFNAPFRGMASSAGVGSGKIRTVIGAVVDVQFEQDNLPAILNALTIDRGEGNKLVLEVAQHLGENTVRTIAMDGTEGLVRGTSVADTGAPITIPVGRGTLGRIINVCGEPIDERGPIEATKFLPIHADPPTFAEQSTTAEVLETGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGFSVFCGVGERTREGNDLYREMKETGVINLEGESKVTLVFGQMNEPPGARARVALTGLTIAEYFRDEEGQDVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGALQERITTTQKGSVTSVQAVYVPADDLTDPAPATTFAHLDATTVLSRGISELGIYPAVDPLDSKSRLLDIDVVGQEHYDVASNVQQTLQAYKSLQDIIAILGMDELSEQDKLTVERARKIQRFLSQPFTVAEVFTGIEGRLVSLKDTVRSFKEILDGKHDALPEAAFYMVGGIEEVVAKAEKLAAESK
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27373333).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (PubMed:27373333).  Subunits alpha/ATP1 and beta/ATP2 form the catalytic core in F(1) (PubMed:27373333).  Rotation of the central stalk against the surrounding alpha/ATP1(3)beta/ATP2(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta/ATP2 subunits (PubMed:27373333).
What are the official names of this protein?
ATP synthase subunit beta, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: HOXF_CUPNH
Sequence: MDSRITTILERYRSDRTRLIDILWDVQHEYGHIPDAVLPQLGAGLKLSPLDIRETASFYHFFLDKPSGKYRIYLCNSVIAKINGYQAVREALERETGIRFGETDPNGMFGLFDTPCIGLSDQEPAMLIDKVVFTRLRPGKITDIIAQLKQGRSPAEIANPAGLPSQDIAYVDAMVESNVRTKGPVFFRGRTDLRSLLDQCLLLKPEQVIETIVDSRLRGRGGAGFSTGLKWRLCRDAESEQKYVICNADEGEPGTFKDRVLLTRAPKKVFVGMVIAAYAIGCRKGIVYLRGEYFYLKDYLERQLQELREDGLLGRAIGGRAGFDFDIRIQMGAGAYICGDESALIESCEGKRGTPRVKPPFPVQQGYLGKPTSVNNVETFAAVSRIMEEGADWFRAMGTPDSAGTRLLSVAGDCSKPGIYEVEWGVTLNEVLAMVGARDARAVQISGPSGECVSVAKDGERKLAYEDLSCNGAFTIFNCKRDLLEIVRDHMQFFVEESCGICVPCRAGNVDLHRKVEWVIAGKACQKDLDDMVSWGALVRRTSRCGLGATSPKPILTTLEKFPEIYQNKLVRHEGPLLPSFDLDTALGGYEKALKDLEEVTR
What is the function of this protein?
Subunits alpha and gamma of HoxS constitute an NADH--oxidoreductase.
What are the official names of this protein?
NAD-reducing hydrogenase HoxS subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the complex I 51 kDa subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LPXK_STUS1
Sequence: MSVAERLQRAWYQGHPALCLLAPLELLYRRVVEARRRRFLEDPNTSYRAPVPVVVVGNITVGGTGKTPLILWLIEHCQRRGLRVGVVSRGYAAEPPTLPWRVRAEHPAQHCGDEPLLIVQRTGVPLMIDPDRARAVRALLQQEPLDLILSDDGLQHYRLARDLELVLIDAARGLGNGRCLPAGPLREPPERLGEVDAVLFNGAAADTVEGYAFSLQPVGLVELSTGRRWPLDHYPAGQQLHAVAGIGNPQRFFDTLETLHWRPIPHAFADHADYSPEQLKFSPELPLVMTEKDAVKCRAFAPPGWSYLQVQAVPSTAFVTWFDDQLARLLPDLS
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: ARIR_ECOLI
Sequence: MLEDTTIHNAITDKALASYFRSSGNLLEEESAVLGQAVTNLMLSGDNVNNKNIILSLIHSLETTSDILKADVIRKTLEIVLRYTADDM
What is the function of this protein?
Probably a connector protein for RcsB/C regulation of biofilm and acid-resistance, providing additional signal input into the two-component signaling pathway.  May serve to stimulate biofilm maturation, via the Rcs phosphorelay.  Regulates expression of genes involved in acid-resistance and biofilm formation, including the RcsB/C two-component system.  May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition.  Also confers resistance to H(2)O(2).  Overexpression at 28 and 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression.  Both of these effects require RcsB; AriR probably acts upstream of the RcsB/C system to stimulate the activity and not transcription of RcsB/C.  5-fluorouracil reduction in biofilm formation requires this protein.
What are the official names of this protein?
Probable two-component-system connector protein AriR.
What is the protein family that this protein belongs to?
Belongs to the AriR family.
Protein: HFB2A_ARATH
Sequence: MNSPPVDAMITGESSSQRSIPTPFLTKTFNLVEDSSIDDVISWNEDGSSFIVWNPTDFAKDLLPKHFKHNNFSSFVRQLNTYGFKKVVPDRWEFSNDFFKRGEKRLLREIQRRKITTTHQTVVAPSSEQRNQTMVVSPSNSGEDNNNNQVMSSSPSSWYCHQTKTTGNGGLSVELLEENEKLRSQNIQLNRELTQMKSICDNIYSLMSNYVGSQPTDRSYSPGGSSSQPMEFLPAKRFSEMEIEEEEEASPRLFGVPIGLKRTRSEGVQVKTTAVVGENSDEETPWLRHYNRTNQRVCN
What is the function of this protein?
Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
What are the official names of this protein?
Heat stress transcription factor B-2a, AtHsfB2a, AtHsf-22, Heat shock factor protein 6, HSF 6, Heat shock transcription factor 6, HSTF 6.
What is the protein family that this protein belongs to?
Belongs to the HSF family. Class B subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: GLGC_RIPO1
Sequence: MKKVLAIILGGGAGTRLYPLTKLRAKPAVPLAGKYRLIDIPLSNCINSEILKIYVLTQFNSASLNRHLTRTYNFTGFSDGFVEVLAAQQTAENPKWFQGTADAVRQYLWAFQEWDIDEYLILSGDHLYRMDYRDFIQRHRETGADITLSVVPIDEERASSFGLMKIDDHGRVVDFSEKPKGDELKQMQVDTTVLGLTPEQAKESPYIASMGIYVFKKEVLAQLLEENPDQTDFGKEIIPFSAKDYNLQAYLFKGYWEDIGTIKAFYEANLALNRQPSPRFSFYNEEYPIYTRSRYLPPTKALNCTITESMVSEGCILKDCRIHNSILGIRTRIEANCTIEDTMLMGADYYESPSLRESKAQEGKIPMGIGEGSTIRRAIVDKNARIGRNVTIVNKENIDESNQEESGFYIRNGIVVILKNATIADGTVI
What is the function of this protein?
Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen.  Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.
What are the official names of this protein?
Glucose-1-phosphate adenylyltransferase, ADP-glucose pyrophosphorylase, ADPGlc PPase, ADP-glucose synthase.
What is the protein family that this protein belongs to?
Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
Protein: ALGB_PSEAE
Sequence: METTSEKQGRILLVDDESAILRTFRYCLEDEGYSVATASSAPQAEALLQRQVFDLCFLDLRLGEDNGLDVLAQMRVQAPWMRVVIVTAHSAVDTAVDAMQAGAVDYLVKPCSPDQLRLAAAKQLEVRQLTARLEALEDEVRRQGDGLESHSPAMAAVLETARQVAATDANILILGESGSGKGELARAIHTWSKRAKKPQVTINCPSLTAELMESELFGHSRGAFTGATESTLGRVSQADGGTLFLDEIGDFPLTLQPKLLRFIQDKEYERVGDPVTRRADVRILAATNRDLGAMVAQGQFREDLLYRLNVIVLNLPPLRERAEDILGLAERFLARFVKDYGRPARGFSEAAREAMRQYPWPGNVRELRNVIERASIICNQELVDVDHLGFSAAQSASSAPRIGESLSLEDLEKAHITAVMASSATLDQAAKTLGIDASTLYRKRKQYGL
What is the function of this protein?
Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes.  Positive regulator of the alginate biosynthetic gene AlgD.
What are the official names of this protein?
Alginate biosynthesis transcriptional regulatory protein AlgB.
Protein: ISPF_BIFLO
Sequence: MGSVGVLIGQGFDAHRFAPAGSGRELWIAGLYWPVPDSCSEADAAKYEGIEGDSDGDVAAHALIDALLAAARLGDIGSLFGVGADAHGAGMHGIDMLQEVVAHLASNGYTPASASVAIIGNRPKIGTRRAEAEAALSAAVGCPVSVTATTTDHMGFTGHGEGIAAIANALVEKI
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: PDE2A_MOUSE
Sequence: MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPQPCADSLQDALLSLGAVIDIAGLRQAARDALSAVLPKVETVYTYLLDGESRLVCEDPPHELPQEGKIREAVISQKRLSCNGLGPSDLLGKPLARLVAPLAPDMQVLVIPLLDKETGSVAAVILVHCGQLSDSEEQSLQVVEKHALVALRRVQALQQRRPEAVQNTSVDASEDQKDEKGYTDHDRKILQLCGELFDLDATSLQLKVLQYLQQETQATHCCLLLVSEDNLQLSCKVIGDKVLGEEVSFPLTMGRLGQVVEDKQCIQLKDLTSDDVQQLQNMLGCELQAMLCVPVISRATDQVVALACAFNKLGGDFPTSSFTDEDEHVIQHCFHYTGTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVATTGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNFANFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMHAFSVSHFCYLLYKNLELSNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDLQKMAEVGYDRNNRQHHRLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPVNGCCSLEG
What is the function of this protein?
Regulates mitochondrial cAMP levels and respiration (PubMed:21724846).  Involved in the regulation of mitochondria morphology/dynamics and apoptotic cell death via local modulation of cAMP/PKA signaling in the mitochondrion, including the monitoring of local cAMP levels at the outer mitochondrial membrane and of PKA-dependent phosphorylation of DNM1L (PubMed:28463107).
What are the official names of this protein?
cGMP-dependent 3',5'-cyclic phosphodiesterase, Cyclic GMP-stimulated phosphodiesterase, CGS-PDE, cGSPDE.
What is the protein family that this protein belongs to?
Belongs to the cyclic nucleotide phosphodiesterase family. PDE2 subfamily.
What are the subcellular locations of this protein?
[Isoform PDE2A1]: Cytoplasm. SUBCELLULAR LOCATION: [Isoform PDE2A2]: Mitochondrion matrix. Mitochondrion inner membrane. Mitochondrion outer membrane. SUBCELLULAR LOCATION: [Isoform PDE2A3]: Cell membrane; Lipid-anchor.
Protein: GP149_RAT
Sequence: MSFFLSNLTNDSRLWKVSHNSTDLMNSPETLTLSLFCLICLMTLVALVGSIFSLVSLLTMQYRTVVSMLVTSWSVDDLLSVLSVAIFMVLQWPREAPGYFQSLCTTSALLYMCQGLSSNLKATLIVFYNFYTMHRTVVSQSSSWRSGQVLGVALTVWAVSLLLASLPLCGWGVFVRTPWGCLTDCSSPYVLLLFAVYASAFGLLAVLSVPLTHQLLCSEEPPRLHANYQEISRGASTPGTPAAGGRVLCLLPEDVEIPALPGTGSSLSSDMVFAPGQPAASSAGAGKRENLWTPRGSSSFPVSLAQKRFALILALTKVILWLPMMIHMVVKHVVGFQSLPVDMLSFLLTLLASTVTPVFVLSKRWAHLPCGCIINCQPDTYSVAFDGKKSKRKGFEFNLSFQQSYGLYKMTHADYYDDDDENPISYHNPKKYECEATKEPREDNHGVFNTITVEISTTPPLDSATLTGVNKCTNTDIPEPKQAVSEEKGAFSIKTECAINYGEATSFEGPERRLSHEETQKPDLSDWEWCRSKSERTPRQRSGGGLAIPICAFQGTVSLQAPTGKTLSLSTYEVSAEGQKITPPSKKIEVYRSKSVGHEPNSEESPSTFADTNVKIHLEVLEICDNDEALDTVSIISNISQSSTKVRSPSLRYSRKENRFVSCDLGETASYSLFLPTSDPDGDINISIPDTVEAHRQNSRRQHQDRDGYQEEIQLLNKAYRKREAESKGN
What is the function of this protein?
Orphan receptor.
What are the official names of this protein?
Probable G-protein coupled receptor 149, Induced early in differentiating astrocytes gene protein.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: NUOI_BURP1
Sequence: MTAIQQFFKTFFLTELLKGLALTGRYTFKRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPALAITIESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKDMLLAVGDRYEKEIAAAKAADARYR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit I, NADH dehydrogenase I subunit I, NDH-1 subunit I.
What is the protein family that this protein belongs to?
Belongs to the complex I 23 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CBIN_NOSS1
Sequence: MNQSKQSLSNWLLIGGVIALAVLPLIFVRDAEFTGADSQAEKAISEVKPGYEPWFKPLFEPPSGEVESLLFSSQAALGAGIIGYAVGLYKGRSQQQRHKE
What is the function of this protein?
Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
What are the official names of this protein?
Cobalt transport protein CbiN, Energy-coupling factor transporter probable substrate-capture protein CbiN, ECF transporter S component CbiN.
What is the protein family that this protein belongs to?
Belongs to the CbiN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PSH1_YEAST
Sequence: MGDELHNRLLHQNDGTKDAILYKIIESLVCSICHDYMFVPMMTPCGHNYCYGCLNTWFASNTQKELACPQCRSDITTIPALNTTLQQYLSFILEKLRDQNDESFKKLLTTKTKEENDYKNDKEKDTLFDKVFKNSALAVADDSDDGITRCSNCHWELDPDEVEDGNVCPHCNARIRNYAGGRDEFDEEEYSEGELDEIRESMRRRRENRFASTNPFANRDDVSSEDDDSSEEEPMREHIPLGRWARSHNRSIAVDAVDDEDDEEEDEEEEEEMDSDLKDFIEDDEDDEDEDGSRRNLVLSALKNRHVIITDDEEEEQRRHATEEEDRDSDFYEHNDDGFVSGDSLDEDQKEVTRIQSSSDSEDRSLSYSGSSDVKDNNDDNTEELDDPQPKRQKRFRVVLGDSDDE
What are the official names of this protein?
RING finger protein PSH1, POB3/SPT16 histone-associated protein 1.
What are the subcellular locations of this protein?
Nucleus.
Protein: MIAB_LEPIN
Sequence: MSVLEQEKKSGKVYIETYGCQMNEYDSGIVSSLMRDAEYSTSSDPENSDIIFLNTCAIRENAHAKIYNRLQSLGYLKKRNPNLVIGVLGCMAQNLGDDLFHQELPLDLVVGPDNYRSLPELIQRIRKGENSISLTRLSKIETYDEIEPRVVNGIQAFVTIMRGCNNFCTFCVVPYTRGRERSRDPKSIVREVQDLVQKGIRQITLLGQNVNSYKEQDTDFAGLIQMLLDETSIERIRFTSPHPKDFPTHLLQLMSENPRFCPNIHLPLQAGNTRVLEEMKRSYSKEEFLDVVKEIRNIVPDVGITTDIIVGFPNETEEEFEDTLAVVREVQFDMAFMFKYSEREGTMAQRKLPDNVPEEVKSARLTKLVDLQTSISHEQNRARIGRVYSILIENISRKSEKQLCGRTPCGRMTVFPLPQETNVSGMIGSTVSVQIESATSATLKGRILA
What is the function of this protein?
Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
What are the official names of this protein?
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase, (Dimethylallyl)adenosine tRNA methylthiotransferase MiaB, tRNA-i(6)A37 methylthiotransferase.
What is the protein family that this protein belongs to?
Belongs to the methylthiotransferase family. MiaB subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_PHOLL
Sequence: MQVLSSLKTAKTRHPDCKIVSRRGRLYVICKSNPRFKAVQGKKKRR
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GGLO1_ARATH
Sequence: MAFWLSLIFFCFCTFASSTPPDDPVKCESGNNMCTVTNSYGAFPDRSICEAAKVEYPKTEAELVSIVAAATRAGQKVRVVTRYVHSIPKLVCTDGKDGVLISTKFLNNVVGTNPEAKTLTVESGVTLRQLIGEAAELELALPHAPYWWGLTVGGLMGTGAHGSSLWGKGSAVHDYVSEIRMVSPGLASDGYVKVRVLSETIDPDEFRAAKVSLGVLGVISQVTFQLQPMFKRSLTFVMQNDSDFGDQAVTFGEKHEFADFLWLPSQGKVVYRMDDRVPVNTSGNGLFDFFPFRPQLSVALAIIRSLEESEESSGDANDKCARAEQITSFLFSISYGVTNNGMEFTGYPVIGKQNHMMSSGTCLDSHQDGLITSCPWDPRIKGQFFHQTAFSIPLTRVKGFINDIKALVKIEPKSLCALERSNGILIRYVTSSPAFLGKEEKALDFDLTYYRSKDDPLAPRLYEDFIEEIEQMAIFKYNALPHWGKNRNLAFDGVIRKYKNANTFLKVKERFDPLGLFSTEWTNQILGLKGNVTIVKEGCALEGLCVCSDDAHCAPKKGYLCRPGKVYTKARVCTHVKSVNGYDDHTKFNLMFNRI
What is the function of this protein?
May be involved in the biosynthesis of ascorbic acid.
What are the official names of this protein?
Probable L-gulonolactone oxidase 1, AtGulLO1.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: YIDD_CLOBK
Sequence: MKNLLICIIKMYRKYISPLKRPSCRFYPTCSQYSLEAIEKYGALKGTLISIKRILKCHPFNKGGYDPVK
What is the function of this protein?
Could be involved in insertion of integral membrane proteins into the membrane.
What are the official names of this protein?
Putative membrane protein insertion efficiency factor.
What is the protein family that this protein belongs to?
Belongs to the UPF0161 family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein; Cytoplasmic side.