PharMolix/UniProtQA huggingface dataset:
Protein: XNI_ECO81
Sequence: MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGVQPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDMHIDGNLQQLRLVR
What is the function of this protein?
Has flap endonuclease activity.  During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment.
What are the official names of this protein?
Flap endonuclease Xni, FEN.
What is the protein family that this protein belongs to?
Belongs to the Xni family.
Protein: PHTF2_HUMAN
Sequence: MASKVTDAIVWYQKKEFLSVATTAPGPQQVLPGYCQCSLKDQGLFIQCLIGAYDQQIWEKSVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLVRGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGVISDLLGFNLKLWKIKS
What are the official names of this protein?
Protein PHTF2.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: EF112_ARATH
Sequence: MHSGKRPLSPESMAGNREEKKELCCCSTLSESDVSDFVSELTGQPIPSSIDDQSSSLTLQEKSNSRQRNYRGVRQRPWGKWAAEIRDPNKAARVWLGTFDTAEEAALAYDKAAFEFRGHKAKLNFPEHIRVNPTQLYPSPATSHDRIIVTPPSPPPPIAPDILLDQYGHFQSRSSDSSANLSMNMLSSSSSSLNHQGLRPNLEDGENVKNISIHKRRK
What is the function of this protein?
Probably acts as a transcriptional activator.  Binds to the GCC-box pathogenesis-related promoter element.  May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity).
What are the official names of this protein?
Ethylene-responsive transcription factor ERF112.
What is the protein family that this protein belongs to?
Belongs to the AP2/ERF transcription factor family. ERF subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: HUTU_PHOLL
Sequence: MTAQNSKFRSVGIRAPRGTQLTAKSWLTEAPLRMLMNNLDPEVAENSYELVVYGGIGRAARNWECYDKIIETLKELEDDETLLIQSGKPVGVFKTHSNAPRVLIANSNLVPHWATWEHFNELDAKGLAMYGQMTAGSWIYIGSQGIVQGTYETFVEAGRQHYNGNLQGRWVLTAGLGGMGGAQPLAATLAGACSLNIECQQSRIDFRLRTGYVDEQAKDLDDALTRIEKYTQEGKAISIALCGNAAEILPELVRRGVRPDLVTDQTSAHDPLNGYLPKNWSWEEYRQRAISAPEEVIKAAKSSMVEHVKAMLIFQQQGIPVFDYGNNIRQMAYEVGVENAFDFPGFVPTYIRPLFCRGIGPFRWVALSGDPQDIYKTDAKVKELLPDDQHLHHWLDMARERISFQGLPARICWVGLGQRAKLGLAFNEMVRSGELSAPIVIGRDHLDSGSVASPNRETESMCDGSDAVSDWPLLNALLNTASGATWVSLHHGGGVGMGFSQHAGMVIVCDGTDEAAERIARVLHNDPATGVMRHADAGYEIAIHCAKEQGLDLPMLNTK
What is the function of this protein?
Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.
What are the official names of this protein?
Urocanate hydratase, Urocanase, Imidazolonepropionate hydrolase.
What is the protein family that this protein belongs to?
Belongs to the urocanase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPC24_YEAST
Sequence: MSQKDNLLDNPVEFLKEVRESFDIQQDVDAMKRIRHDLDVIKEESEARISKEHSKVSESNKKLNAERINVAKLEGDLEYTNEESNEFGSKDELVKLLKDLDGLERNIVSLRSELDEKMKLYLKDSEIISTPNGSKIKAKVIEPELEEQSAVTPEANENILKLKLYRSLGVILDLENDQVLINRKNDGNIDILPLDNNLSDFYKTKYIWERLGK
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Kinetochore protein SPC24.
What is the protein family that this protein belongs to?
Belongs to the SPC24 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: PHZB2_PSEAE
Sequence: MLDNAIPQGFEDAVELRRKNRETVVKYMNTKGQDRLRRHELFVEDGCGGLWTTDTGSPIVIRGKDKLAEHAVWSLKCFPDWEWYNIKVFETDDPNHFWVECDGHGKILFPGYPEGYYENHFLHSFELDDGKIKRNREFMNVFQQLRALSIPVPQIKREGIPT
What is the function of this protein?
Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control.  PhzB2 (operon phzA2B2C2E2F2G2) has a role in the biosynthesis of the phenazine during both planktonic growth and biofilm development, and in host infection during biofilm development.
What are the official names of this protein?
Phenazine biosynthesis protein PhzB2.
What is the protein family that this protein belongs to?
Belongs to the PhzA/PhzB family.
Protein: Y2600_YERPE
Sequence: MKTKLNELLEFPCSFTYKVMGIAEPQLVDQVVEVVQRHAPGEYTPQVKPSSKGNYHSVSITITATHIDQVETLYEELGNLELVKMVL
What are the official names of this protein?
UPF0250 protein YPO2600/y1174/YP_1113.
What is the protein family that this protein belongs to?
Belongs to the UPF0250 family.
Protein: H13L1_CYRHA
Sequence: MKTAIFTVVLALAVFAVLSFGWEANEKALSEEFTELIHEKEAASETEARECRYFWGECHDHMPCCDWLVCRYKWLITYNICVWNRTFPEK
What is the function of this protein?
Ion channel inhibitor.
What are the official names of this protein?
U7-theraphotoxin-Hhn1j, U7-TRTX-Hhn1j, Hainantoxin-XIII-12, HNTX-XIII-12.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 13 (Hntx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SUB1_TRIEQ
Sequence: MGVFRFISISLAAVSAANAAQILSMPHAQTVPHSYIVMMKDDTSDDDFNHHQSWLQSTHTHNITRRATIQNAGMRHKYNFRKMKGYSGIFDEETIKDIAKDPKVMFVEPDTIISVNGKVEQSNVPSWGLARISNSQPGANSYVYDSSAGEGITVYSVDTGVDINHEDFEGRAIWGSNQVNDGDDRDGSGHGTHTSGTMVGKEFGIAKKAKLVAVKVLGNDGSGPTSGIVAGINWCVEHARQNGGNDKAVMNMSLGGSSSSALNRAAAQAVEQGMFLSVAAGNENQDARSSSPASEPSVCTVGSSAEDDSRSSFSNWGPALDLFAPGSNIISARPGGGSQSMSGTSMAAPHVAGLAAYLMALEGISGGAVCDRLKELGSSSITDVGPGTPTNVLISNGGAKGGNPKPAPGPSPNPSQPSEPQQPAPSQPGEPGESFPGEPFPGEPFPGEPFPGESSPGESAPAPAPMPPSPQHPHTPYPGGDNFDFDGYWKKYFGGEHWRKMFGSFWN
What is the function of this protein?
Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity.
What are the official names of this protein?
Subtilisin-like protease 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S8 family.
What are the subcellular locations of this protein?
Secreted.
Protein: IXTPA_LEPIC
Sequence: MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKENALIKAKELFYLTKIPSIADDSGICVSALKDEPGVYSARFGGPELNDEGRALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGIYGFGYDPIFIFPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: RL17_OLEA2
Sequence: MRHRKSGRKLNRSSSHRSALFRNMAKSLLTYGKIRTTEAKAKELRGVVEPLITLALRNDLHARRQAYKVLGSHQLVKRLFDEIGPKFVGVPGGYTRVLKLGAPRPGDNAPMAVIELTRLGDAEAAAKEAPAKEVAEEKAAKPAKKAAPKKAEKEEAEDAAEA
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: AMPA_ECO27
Sequence: MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_ACICJ
Sequence: MSLDHATVRRIAKLARIRLDEEEVPRLAGELNAILGYVEQLAEVDVEGVAPLSGGAQMALRMREDEVTDGRYPDRVLANAPERIGDFFAVPKVVE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C, Asp/Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: MVP_RDVA
Sequence: MDTETLCLITADSGKVYGILKAIFGDESEIVKKLIDFDVSIRVVPLNLGLLNIFRDNAADLDNADLMKRRFGNTMGSRIVEAYRRSQDSKYKRNVCKTTGLLVCLFGGGLGLSREADKHKKFVEGKSHNILSVEMLKRALSIGGQNVDANKISSFWFATYTIFTTVYSPRLRYQAGSSKRIIALSESRNQYRSNLFWDLRDDSSHEVMSMVHVLSALFASALTAYISTRVAHELTQGNDERESLNNVLVWLKTLTFEPSTIALIAYIWLVSPTDAQATITIGSVMESESSDDFPDIVKILSYTSNTMLPVQLLEDGRTAYCSVADGYTTHTTALTLITDYNSSHMSDKFGVLINIVKFEHAYALHYVHHKPRDGKEMTITSPSSEMMFTSVVVTPLSSYPLIHARNAVIDWLRTFVHMFPDSGSLVIPADSYTWIHNLAQDMFPWVRLSTTLDIRDDHYFQVLCDCLSLEHDSRNHTKVEKLIKYMKASVYNFTSEARGNMLLAITVYK
What is the function of this protein?
Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding.  The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier (By similarity).  Increases virus accumulation and symptom severity.
What are the official names of this protein?
Movement protein, Non-structural protein 6, Pns6.
What are the subcellular locations of this protein?
Host cell junction, host plasmodesma. Host cytoplasm. Note=Constituent of spherical cytoplasmic structures, called virus factories, that appear early after infection and are the site of viral replication and packaging.
Protein: VPS70_YEAST
Sequence: MRMIQRERKREKEEGQLKERTVVNMADPDDNEAEATGLQQYSGETTRDDNEESMNDSFTLTSRNRGRSNTISSIVSGYEIMKEHMDKEKFMYLILASLLLYMGFVAAFAPRTSLSRDFRRFHSSRLTNAEVYRIYLNSLQQENRAKEHVYKYAGYMSNGASDSSTFKYTLDEFLDMGYKPKVEKYYPWIGEPVDTNVAPLENGKVVYEASMIEDRVKGDPASHARKRQKGFHQYSKNGSVTARYVFCNYGSISDYKLLLKKNIDIEDKIHIVRSGKILPGLKVKNAELYGASSVIIYTDPFDDGKVTEENGFLHYPYGPARNPSYIRRDSVNYFSDTPGDPTTPGYPSKDSDTEHMSPVGRVPRIPSVPMSARDVQPILERLNGRGFQIGPGSNIKDFGSFTGPSSSIDKVHLHNELTYNIKEMSSVEVSIPGIFTEGEIIIGAHRDSLASSSAGDANSGSAILLEIARGMSKLLKHGWKPLRPIKLISWDGERSGLLGSTDYAEAHAAILRRRALVYLNLDNAISGTNFHCKANPLLQDVIYEAAKLTEFNGHEDWSLFDHWKYTSNATISLLDGLSSYTSFQYHLGVPAAHFQFNANDTSGAVYHSNSVFDSPTWLEKFTNSDYKLHNTMAMFVGLTTLMLSENELARFNTHVYLKKIYNWYIAWHSNLSSAFPQDDEVNSLAKRVLDLLKVATQEDSIQFDQQNGILYKECREALPVWAFYKKIKSYIKLQRSNSKSKQIDQLFITHRGLKDREWMKYSLLAPSKFEGSVGEVLPGLHEGLADIDRNEVIQWLTILLSQFSNVRYLLQ
What is the function of this protein?
Involved in vacuolar protein sorting.
What are the official names of this protein?
Vacuolar protein sorting-associated protein 70.
What is the protein family that this protein belongs to?
Belongs to the peptidase M28 family. M28B subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: YOHJ_SALSV
Sequence: MSKSLNIIWQYIRAFVLIYACLYAGIFLASLLPITIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAISTLVVFVVVSWSSHLIHGERKVVGQKGTKK
What are the official names of this protein?
UPF0299 membrane protein YohJ.
What is the protein family that this protein belongs to?
Belongs to the UPF0299 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEU1_BURA4
Sequence: MTDKLIIFDTTLRDGEQSPGASMTKEEKIRIAKHLERMKVDVIEAGFAASSNGDFDAIHTIAGLVKDSTICSLARANDKDIQRAADALKPANSARIHTFIATSPLHMEKKLRMTPDQVFEQARLAVRFARKFTDNVEFSPEDGSRSDLDFLCRVLEAVIAEGATTINIADTVGYGVPELYGNLVKTLRERIPNSDKAIFSVHCHNDLGMAVANSLAGVKIGGARQVECTINGLGERAGNTSLEEIVMAVKTRKDYFGLDVGLDTTQIVPTSKLVSQITGFVVQPNKAVVGANAFAHASGIHQDGVLKARDTYEIMRAEDVGWTANKIVLGKLSGRNAFKQRLQELGVSLDSETELNAAFMRFKDLADRKSEIFDEDIIAIVSEESALAQEQEHYKFVSLSQRSETGEQPQAKVVFALDGKEVTGEARGNGPVDATFNAIEGEVGSGSELLLYSVNAITTGTQAQGEVTVRLSKSGRIVNGVGTDPDIVAASAKAYIAALNKLHSKDDKLNPQRS
What is the function of this protein?
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
What are the official names of this protein?
2-isopropylmalate synthase, Alpha-IPM synthase, Alpha-isopropylmalate synthase.
What is the protein family that this protein belongs to?
Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
Protein: FABZ_COXB1
Sequence: MNVMNITDIKKYIPHRYPFLLIDRVIKIEKDKSLVAIKNVTVNEPFFTGHFPVRPVMPGVLIIESLAQAAGILIVKSLNLPEGHKDIYFFAGVDNARFKRVVEPGDQLTLEVKVLKVHRGLWKFEGKATVDDQLACKAELMTIKG
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RPOC_ACIAC
Sequence: MKSLLDLFKQFTPDEHFDAIRIGMASPEKIRSWSFGEVKKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIDLAAPCAHIWFLKSLPSRLGLVLDMTLRDIERVLYFEAYVVTDPGMTPLKKFGIMSEDDHDAKRKEYGDEFIAKMGAEGIKDLLEGIDIDLEIEKLRGDLTGSEVKVKKNAKRLKVLEAFKKSGIKPEWMVLDVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNSRLRRLLELKAPEIIARNEKRMLQEAVDSLLDNGRRGKAMTGANKRALKSLADMIKGKSGRFRQNLLGKRVDYSGRSVITVGPTLKLHQCGLPKLMALELFKPFIFSRLEQMGIATTIKAAKKEVESGTPVVWDILEEVIKEHPVMLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSVEAQMEARTLMLASNNVLFPASGEPSIVPSQDVVLGLYHATRDKINGKGEGLVFADTGEVQRALDAGQVELHAKISVRLTEWTKDKASGEFVPSTSLVDTTVGRALLSEILPKGLPFSNINKALKKKEISKLINVSFRKCGLKETVVFADKLLQNGFRLATRAGFSVAIDDMLVPPQKTEILARAEAEVKEIEQQYVSGLVTAGERYNKVVDIWGKAGDDVSKVMMDQLKVEKTTDRHGKEVNQESFNAIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVVTEEDCGTTNGSVMRAIVEGGEVIESLRERVLGRSTAEEVLHPETRAVLVPAGQMLDEDTLEELEAAGVDEVKVRTALTCETRYGLCAKCYGRDLGRGGLINLGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAIASTVEAKSNGVIGFNATMRYVTNSKGELVVIARSGEVIIQDEHGRERERHKVPYGATLTVKADQQVKAGTILANWDPLTRPIITEFAGQVKFENIEEGLTVAKQVDDVTGLSTLVVIDPKRRGSAKVVRPQVKLVDANGAEVKIPGTDHSVTIGFQVGALIQVRDGQDVGPGEVLARIPVEGQKTRDITGGLPRVAELFEARSPKDKGMLAEITGTVSFGKETKGKVRLQITDPDGKVWDELVPKEKNVLVHEGQVVNKGELIVDGPADPQDILRLLGIEELSRYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVENPGESGYIAGEQVERSEILNTNEQLQSEGKIPATYSNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDELRGLKENVIVGRLIPAGTGLAYHQARKAKEAMDDAERRAIAEAEAAEMATTGSDEAPEVEGSGVESGSAE
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: RL15_CANLF
Sequence: MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR
What is the function of this protein?
Component of the large ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
60S ribosomal protein L15.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL15 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CRCB_AGRFC
Sequence: MINIALVATGGAIGSVFRYLVGVWSMRLAGPNFPWGTLAVNIVGSFLIGLLVELVARRLNASIEMRLFLVTGVLGGFTTFSSFSLDAVSLFERGALGLSAFYILASLVVSIAAVFAGLALGRNLF
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: TOP1_CRIGR
Sequence: MSGDHLHNDSQIEADFRLNDSHKHKDKHKDREHRHKEHKKDKEKDREKSKHSNSEHKDSEKKHKEKEKTKHKDGSSEKHKDKHKDRDKEKRKEEKIRASGDAKIKKEKENGFSSPPRIKDEPDDDGYFAPPKEDIKPLKRPRDEDDADYKPKKIKTEDIKKEKKRKLEEEEDGKLKKTKNKDKDKKGAESDNKKKKPKKEEEQKWKWWEEERYPEGIKWKFLEHKGPVFAPPYEPLPEGVKFYYDGKVMKLSPKAEEVATFFAKMLDHEYTTKEIFRKNFFKDWRKEMTNDEKNVITNLSKCDFTQMSQYFKDQSEARKQMSKEEKLKIKEENEKLLKEYGFCVMDNHRERIANFKIEPPGLFRGRGNHPKMGMLKRRIMPEDIIINCSKDAKVPSPPPGHKWKEVRHDNKVTWLVSWTENIQGSIKYIMLNPSSRIKGEKDWQKYETARRLKKCVDKIRNQYREDWKSKEMKVRQRAVALYFIDKLALRAGNEKEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEKRVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKELTAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDLKSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLDPRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF
What is the function of this protein?
Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex.  Introduces a single-strand break via transesterification at a target site in duplex DNA.  The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand.  The free DNA strand then rotates around the intact phosphodiester bond on the opposing strand, thus removing DNA supercoils.  Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.  Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.  Involved in the circadian transcription of the core circadian clock component BMAL1 by altering the chromatin structure around the ROR response elements (ROREs) on the BMAL1 promoter.
What are the official names of this protein?
DNA topoisomerase 1, DNA topoisomerase I.
What is the protein family that this protein belongs to?
Belongs to the type IB topoisomerase family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm. Note=Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumoylated forms found in both nucleoplasm and nucleoli.
Protein: PATH2_ARATH
Sequence: MERSDSRDFYNFAKTSSDNNSALFDASQYEFFGQSLEEVELGGLDDDGTVRGHVDDEEYHLFDKREGAGLGSLSDMDDLATTFAKLNRNVTGPKHLGVIGDRGSGSFSRESSTATDWTQDNEFTSWLDQHTVEEQVQEASWSSQPQSSPNSNSLYRTSSYPQQQTQLQHYSSEPIIVPESTFTSFPSPGKRSQQSSPSHIHRAPSLPGGSQSNFSAPNASPLSNSTFHLSGLSHGPSHYGNNLARYASCGPTLGNMVQQPPHWVTDPGLLHGDHSALLHSLMQQQHLQQLPPRNGFTSQQLISLQQRQSLAHLAALQSQLYSSYPSPSHKALFGVGEVREHKHKSSHRSRKNRGGISQQTSDLASQKSESGLQFRSKYMTSEEIESILKMQHSNSHSSDPYVNDYYHQARLAKKSSGSRTKPQLYPSHLKDHQSRSRNSSDQQPQVHVDALGKITLPSICRPRALLEVDSPPSSGHKHLEDEPLVAARVTIEDAFGVLIDIVDIDRTLQFNRPQDGGAQLRRKRQILLEGLATSLQLVDPFSKTGQKTGLTTKDDIVFLRITTLPKGRKLLTKYLQLLVPGTEIARVVCMAVFRHLRFLFGGLPSDSLAAETIANLAKAVTVCVQAMDLRALSACLAAVVCSSEQPPLRPIGSSSGDGASVVLVSLLERAAEVIVAVVPPRVSNHGNPNDGLWRASFDEFFSLLTKYCRSKYETIHGQNHDNAADVLELAIKREMPAELLRASLRHTNEDQRNFLLNVGRSASPVSESTTTRASASGGQINSEFVRG
What is the function of this protein?
Activator of mRNA decapping.  Involved in mRNA decay via decapping.
What are the official names of this protein?
Protein PAT1 homolog 2, AtPAT1H2.
Protein: TIG_CERS5
Sequence: MQVTETLKEGLKRAYTITVTAAELDAKVQEKLVEAQPDIEMKGFRKGKVPLAMLRKQFGPRLLGDAMQDAIDGAMRDHLETSGDRPAMQPEVRMVDGETWQEGTDVVVEMKYEALPEIPEIETSKVTLERLVVKADEAAVDEALKNLAESAQNFDDRRKGSKAKDGDQIVIDFKGSVDGELFEGGSAEDYPLVLGSGSFIPGFEEQLVGAKVEDEVTVKVTFPTEYGAKHLAGKEAEFACTVKAVKAPKPAEIDDELAKKYGAEDLAALKAQIAERLEAEYKGASRAVLKRALLDQLDTMVSFELPSKLVEAEAHQIAHQLWHEEHPEEHGHNHGTIEPTDEHKALAERRVRLGLLLAEIGRKAEVTVTDAEMTQAVLAQARQYPGQERAYFEFVQKNPQIQQQLRAPIFEDKVVDLILEGATVTEKEVGKDDLQKAIEALDEM
What is the function of this protein?
Involved in protein export.  Acts as a chaperone by maintaining the newly synthesized protein in an open conformation.  Functions as a peptidyl-prolyl cis-trans isomerase.
What are the official names of this protein?
Trigger factor, TF, PPIase.
What is the protein family that this protein belongs to?
Belongs to the FKBP-type PPIase family. Tig subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Note=About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.
Protein: KDPB_BACC3
Sequence: MMRPIVVKEKQIHVVEDEVRQAKTMDRDIVKHAMKQSFAKLNPKVMIKNPIMFVVEIGFIITFILSFLPSHSSSVPGWFNITVSLILLFTVLFANFAEALAEGRGKAQADSLKQSKKDVFANVVKENGDIVQVSATDLRKGDLVIVKQGEMIPSDGEVIKGLASVDESAITGESAPVIKEAGGDFCSVTGGTMVVSDEITIVITSNPGESFIDKMISLVEGAARQKTPNEIALNTVLTSLTLIFLIVVVTLPIFTNYLGFQIDTAVLVALLVCLIPTTIGGLLSAIGIAGMDRVTKFNVLAMSGKAVEAAGDINTIILDKTGTITFGNRMAHTLLPVGNETIEQVGKWAAISSVLDETPEGRSVIEYVKTKSISYNREIAEQGEFVPFKAETRMSGVDLQDGTKVRKGAVGSVIEWVRSQGGTIPKDVNQKADFISKEGGTPLVVAVDNRIYGLIYLKDTVKPGMRERFEQLRQMGIKTVMCTGDNPLTAATIAKEAGVDEFVAECKPEDKIAVIKAEQDKGKLVAMTGDGTNDAPALAQADVGLAMNSGTTAAKEAANMIDLDSNPTKIIEVVGIGKQLLMTRGALTTFSIANDIAKYFAIIPAMFTLAIPQMEALNIMKLTSPLSAILSALIFNAVIIPLLIPLAMKGIAYKPMSSNALLGRNLLIYGLGGVIVPFIGIKVIDIIVGLFI
What is the function of this protein?
Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm.  This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.
What are the official names of this protein?
Potassium-transporting ATPase ATP-binding subunit, ATP phosphohydrolase [potassium-transporting] B chain, Potassium-binding and translocating subunit B, Potassium-translocating ATPase B chain.
What is the protein family that this protein belongs to?
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: CK071_HUMAN
Sequence: MALNNVSLSSGDQRSRVAYRSSHGDLRPRASALAMVSGDGFLVSRPEAIHLGPRQAVRPSVRAESRRVDGGGRSPREPDGRGRSRQARFSPYPIPAVEPDLLRSVLQQRLIALGGVIAARISV
What are the official names of this protein?
Uncharacterized protein C11orf71.