PharMolix/UniProtQA huggingface dataset:
Protein: DNLJ_COLP3
Sequence: MSNVEKKISQLQQQLNQYNHEYYVLDQPSVPDAEYDRLMTALIDLEKTNPELKTIDSPSQKVGGQALKSFTQVTHQLPMLSLDNVFSLDDFHAFVKRVKDRLNDNQAIVFCAEPKLDGLAVSLRYEHGQLIQAATRGDGSVGENITTNIRTIKSIPLKLMGTPGKDFPDIVEVRGEVFMPKASFDALNTLAKKRGEKGFANPRNAAAGSLRQLDSKITAKRNLAFYAYSLGFVGKLSDGGAESTDLTNDFFANSHHERLCQLKRLGLPMCPEVRLLESEQACDAFYQDILAKRSALSYEIDGTVLKVDEISLQKRLGFVARAPRWAIAYKFPAEEELTCVEDVEFQVGRTGAITPVARLKPVFVGGVTVSNATLHNQDEITRLGLKVNDFVVIRRAGDVIPQIVSVVLDKRPDNAVDIVFPTSCPVCDSAVAKPEGEAVLRCTAGLFCAAQRKEAIKHFASRKAHDVDGLGDKLVEQLVDEKLINTPADLFKLTEIQVSTIDRMGKKSATNLINGLEQAKSTTLAKFIYGLGIREVGEATAANLANHFYTLAAIESASLEDLQNVSDVGEVVAKNIINFFKEEHNLAIVSGLSEVMHWPTIEIKSAEELPLAEQIFVLTGTLTQMGRTEAKTALQSLGAKVSGSVSKNTHFVVAGDKAGSKLTKAQDLGISVLTEDGLVALLAEHGITI
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GYRB_BUCAI
Sequence: MKNIYDSSNIKILRGLDAVRKRPGMYIGDTDDGSGLHHMVFEIVDNSIDEALSGYCKEIIVTIHSDNSVSVKDDGRGIPTDIHPEENISAAEVILTVLHSGGKFDNASYQISGGLHGVGISVVNALSEKLELIIDKNKKKYQQIYRHGKPENPLSIIGTTDTTGTYIRFWPSYKTFTNNIKFQYEILSKRLRELSFLNSNIAIYLEDNRTSIKNCYHYKGGIKAFIKFLNAKKTPIHTHIFYFRSTKDQIELEIAMQWNNSHQENILCFTNNIPQKDGGTHLAGFRSGMTRTLNLHIEREGYNKKNKTTIIGEDVREGLTAIISIKIPDPKFSSQTKDKLVSSEARSVIESLINENLIEYLLENPSDSKFIIQKIINAAKVREAARRAREINKKKSILDLGALPGKLSDCQENDPKFSEIYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKSKFDKMILSQEVASLITALGCGIGKNEYNIDKLRYHYIIIMTDADVDGAHIRTLLLTFFYRQLPELIEKGYVYIAQPPLYKLKKGRKEKYIKNDEEMNTYQIKNALKDLVLKSEDNLIINQKLKKFKKIMSEYHYIQIIMKQSKHYFPKLVFNELIYHNHLHNLKDIEIVKEWIYTLAENLNKKDNSNNHYSIEIKENLDKNIFEPTIKISRYAHYTKYDFKEEFLKSKEYLLITNLGESFKKYFSDKVLIEKSGSTYKIDSIKNTWKWLIKQSKRGLFIQRYKGLGEMNPEQLWNTTMNPETRNMLQVTIKDAVSANNLFNTLMGEAVEPRRQFIENNALKAENIDV
What is the function of this protein?
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state.  Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation.  Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings.  Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
What are the official names of this protein?
DNA gyrase subunit B.
What is the protein family that this protein belongs to?
Belongs to the type II topoisomerase GyrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_CLOPS
Sequence: MIKNLLNKRKYITVSSVELNDTELSEDEKPNIPSGMWSKCEKCAKILYTEDLRENFNVCPNCGHHFKLGAYERIKYLTDENTFVEFDKKMIGRNPLDFNGYEEKIKGYQKKSHVIEGVVTGEAYIAQRKVVLCVMDSNFMMGSMGTAVGEKITRAIEYATKNRLPLIIFTCSGGARMQEGIYSLMQMAKVSGAIYRHGRENLLYITVLTNPTTGGVTASFAMEGDIILSEPGCLVGFAGRRVIEGTINEKLPDDFQTAEFLLEKGFIDKIVQRKDLKQVITSLLRMHEVDYE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRGC2_HUMAN
Sequence: MAGNDCGALLDEELSSFFLNYLADTQGGGSGEEQLYADFPELDLSQLDASDFDSATCFGELQWCPENSETEPNQYSPDDSELFQIDSENEALLAELTKTLDDIPEDDVGLAAFPALDGGDALSCTSASPAPSSAPPSPAPEKPSAPAPEVDELSLLQKLLLATSYPTSSSDTQKEGTAWRQAGLRSKSQRPCVKADSTQDKKAPMMQSQSRSCTELHKHLTSAQCCLQDRGLQPPCLQSPRLPAKEDKEPGEDCPSPQPAPASPRDSLALGRADPGAPVSQEDMQAMVQLIRYMHTYCLPQRKLPPQTPEPLPKACSNPSQQVRSRPWSRHHSKASWAEFSILRELLAQDVLCDVSKPYRLATPVYASLTPRSRPRPPKDSQASPGRPSSVEEVRIAASPKSTGPRPSLRPLRLEVKREVRRPARLQQQEEEDEEEEEEEEEEEKEEEEEWGRKRPGRGLPWTKLGRKLESSVCPVRRSRRLNPELGPWLTFADEPLVPSEPQGALPSLCLAPKAYDVERELGSPTDEDSGQDQQLLRGPQIPALESPCESGCGDMDEDPSCPQLPPRDSPRCLMLALSQSDPTFGKKSFEQTLTVELCGTAGLTPPTTPPYKPTEEDPFKPDIKHSLGKEIALSLPSPEGLSLKATPGAAHKLPKKHPERSELLSHLRHATAQPASQAGQKRPFSCSFGDHDYCQVLRPEGVLQRKVLRSWEPSGVHLEDWPQQGAPWAEAQAPGREEDRSCDAGAPPKDSTLLRDHEIRASLTKHFGLLETALEEEDLASCKSPEYDTVFEDSSSSSGESSFLPEEEEEEGEEEEEDDEEEDSGVSPTCSDHCPYQSPPSKANRQLCSRSRSSSGSSPCHSWSPATRRNFRCESRGPCSDRTPSIRHARKRREKAIGEGRVVYIQNLSSDMSSRELKRRFEVFGEIEECEVLTRNRRGEKYGFITYRCSEHAALSLTKGAALRKRNEPSFQLSYGGLRHFCWPRYTDYDSNSEEALPASGKSKYEAMDFDSLLKEAQQSLH
What is the function of this protein?
Plays a role of stimulator of transcription factors and nuclear receptors activities.  Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids.  May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed.  May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure.  Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
What are the official names of this protein?
Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PGC-1-related estrogen receptor alpha coactivator.
What are the subcellular locations of this protein?
Nucleus.
Protein: ATP6_ALIF1
Sequence: MAAPGEALTQSGYIEHHLTNLSLAKLGLVADEASFWNVHIDSLFFSVFTGMLFLWVFRSVAKKATTGVPGKLQCFVEMIVEFVADNVKETFHGRNPLIAPLALTIFCWVILMNLMDLVPIDFLPYPAEHWLGIPYLKVVPSADVNITMAMALGVFALMIYYSIKVKGLGGFAKELALHPFNHPIMIPFNLLLEVISLLAKPLSLGMRLFGNMFAGEVVFILIAAMLPWYLQWVGALPWAIFHILVILIQAFVFMMLTIVYLSMAHEDSDH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YIHY_ESCF3
Sequence: MLKTIHEKARHHTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQQYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNAIWRSKRVRPKIYSFAVYWMILTLGPLLAGASLAISSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
What are the official names of this protein?
UPF0761 membrane protein YihY.
What is the protein family that this protein belongs to?
Belongs to the UPF0761 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SYFA_THESM
Sequence: MELSYQEKVTLIKLRELKKASFDELVKETGLDQVAVMRAILWLQSKGLAKLHEKQKRVVKITELGEKYAKIGLPERRALKLLVEKGKVTLEDLREVLSEDELRPIIGILRKEGWATVRKEDDVLTLELTEKGKEALTKERPIDIALKVLAEKREVEAREIEELLSLKELKTRKIGEEDAKAEREVEITDEGLRIASEGLELKEEVSILTPELIKSGGWKNVEFKHFNIHAPVKRLYPGKKQPYRTFLDKIRRKLIEMGFIEMTVESLIETQFWNFDALFQPQNHPARDWTDTYQLKYPKYGFLPDETLVERVKASHEHGWITGSRGWGYKWDPRTAMLLMPRAHATALSARQLGKGVQIPGKYFAIQRVFRPDVLDRTHLIEFNQVDGFVVGETLTFKHLLGILKRFAVEIAGAKKVKFLPDYYPFTEPSVQMSAYHEELGWVEFGGAGVFREEMTKPLGIDVPVIAWGIGIDRLAMFKLGIDDIRYLFSYDLKWLREAKLVW
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL332_GEOKA
Sequence: MRVNITLACTECGERNYITSKNKRNNPERLELKKYCPRDRKVTLHRETK
What are the official names of this protein?
50S ribosomal protein L33 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: RHAB_ECO81
Sequence: MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWNVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTIYQLRALTEQQPELIPHIAHALLIPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINPNDDRFINPDEMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA
What is the function of this protein?
Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose).  Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate.
What are the official names of this protein?
Rhamnulokinase, RhaB, ATP:L-rhamnulose phosphotransferase, L-rhamnulose 1-kinase, Rhamnulose kinase.
What is the protein family that this protein belongs to?
Belongs to the rhamnulokinase family.
Protein: RL8_AEDAL
Sequence: MGRVIRAQRKGEGSVFTAHTKKRKGEPKLRALDYAERHGYLKGTVKQIIHDPGRGAPLAVVHFRDPYKFNVRKQLFIAAEGMYTGQFVYCGKRAQLQIGNVLPIGLMPEGTIVCNLEEKTGDRGKLARTSGNYASVIAHNPDTKRTRVKLPSGAKKVLPSANRAMVGIVAGGGRIDKPILKAGRAYRKYKVKRNCWPKVRGVAMNPVEHPHGGGNHQHIGKASTVKRGTPPGRKVGLIAARRTGRIRGGKGDEKFKEKEKK
What are the official names of this protein?
60S ribosomal protein L8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARBK2_MOUSE
Sequence: MADLEAVLADVSYLMAMEKSKTAPAARASKKVVLPEPSIRSVMQRYLAERNEITFDKIFNQKIGFLLFKDFCLNEIGEAVPQVKFYEEIKEYEKLDNEEDRLRRSRQMYDAYIMRELLSSTHQFSKQAVEHVQSHLSKKQVTATLFQPYIEEICESLRGDIFQKFMESDKFTRFCQWKNVELNIHLSMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRVKMKQGETLALNERIMLSLVSTGDCPFIVCMTYAFHTPDKLCFILDLMNGGDMHYHLSQHGVFSEKEMRFYASEIILGLEHMHTCFVVYRDLKPANILLDEYGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGTCYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTVNVQLPDAFSPELRSLLEGLLQRDVSQRLGCGGGGARELKEHIFFKGIDWQHVYLRKYPPPLIPPRGEVNAADAFDIGSFDEEDTKGIKLLDCDQDLYKNFPLVISERWQQEVVETIYDAVNADTDKIEARRKAKNKQLGQEEDYAMGKDCIMHGYMLKLGNPFLTQWQRRYFYLFPNRLEWRGEGESRQSLLTMEQIMSVEETQIKDRKCILLRIKGGKQFVLQCESDPEFAQWLKELTCTFNEAQRLLRRAPKFLNKPRAAILEFSKPPLCHRNSSGL
What is the function of this protein?
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
What are the official names of this protein?
Beta-adrenergic receptor kinase 2, Beta-ARK-2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.
Protein: LEC4_SCOPL
Sequence: DAEPPSPAEECAAVKMESCGDDWLYIDENRKVKYFETPKTFQEAQDHCESEDGNLVAMHTEFQKYVVACLSWIYNHKLHRMWIGAGRSEGETQNIDGSDFDYAKWKGGQPDNFGGNEDCIEANFIDWGYLNDVECSEKLPFMCA
What is the function of this protein?
The role of this hemagglutinin in the venom is unknown, because it is masked by the high venom hemolytic activity.  Lectin with specificity to galactose.  Induces hemagglutination.
What are the official names of this protein?
C-type isolectin Sp-CL4.
What is the protein family that this protein belongs to?
Belongs to the true venom lectin family.
Protein: KDSB_BRASB
Sequence: MTQPKILVLIPARMASTRLPGKPLLDIAGLPMIVQVLRRAQEANIGRVAVATDTKEIADAVIAHGGEAVMTRPDHPSGSDRIYEASCKLDPAGEAEIVVNLQGDFPTILPQNIRDVLLPLSDPAVDIATLAAQIHTAEEDAAPSVVKAVGSPIGERRLRALYFTRATAPHGDGPRYHHIGLYAYRRAALERFVSLPPSPLELQEKLEQLRALEAGMRIDIGIVDTVPRGVDTPPDLETARRLLSKA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL3_SALTO
Sequence: MDRQVKGILGAKLGMTQVWDNNRVVPVTVVQAGPCVVSQVRSQEKDGYAAVQLAYGAIDPRKVKKPISGHYAKADVAPRRHIVELRTTDAGEYSSGQEVTVEEFPAGISVDVTGKTKGKGYAGPMKRHGFHGLRASHGVERKHRSPGSIGGCATPGRVFKGTRMAGRMGGVRYTVQNLTVQAVDTENNLLLVRGAIPGPKGALVLVRTAAKAKKGGAAK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: CLIP1_MOUSE
Sequence: MSMLKPSGLKAPTKILKPGSTALKTPAAAAAPVEKTIPSEKASGPPSSETQEEFVDDFRVGERVWVNGNKPGFIQFLGETQFAPGQWAGIVLDEPIGKNDGSVAGVRYFQCEPLKGIFTRPSKLTRKVQAEDEANGLQAAPGRTASPLSTAAATMVSSSPATPSNIPHKPSQSTAKEPSATPQISNLTKTASESISNLSEAGSVKKGERELKVGDRVLVGGTKAGVVRFLGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCQPKYGLFAPVHKVTKIGFPSTTPAKAKAAAVRRVMAATPASLKRSPSASSLSSMSSVASSVSSKPSRTGLLTETSSRYARKISGTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHVGEIEQELALARDGHDQHVLELEAKMDQLRTMVEAADREKVELLNQLEEEKRKVEDLQFRVEEESITKGDLEVATVSEKSRIMELEKDLALRAQEVAELRRRLESSKPPGDVDMSLSLLQEISALQEKLEAIHTDHQGEMTSLKEHFGAREEAFQKEIKALHTATEKLSKENESLRSKLDHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSKGIGTDSAEFAELKTQIERLRLDYQHEIESLQSKQDSERSAHAKEMETMQAKLMKIIKEKEDSLEAVKARLDSAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKYTEQSEVIGNFTSQLSAVKEKLLDLDALRKANSEGKLELETLRQQLEGAEKQIKNLETERNAESSKANSITKELQEKELVLTGLQDSLNQVNQVKETLEKELQTLKEKFASTSEEAVSAQTRMQDTVNKLHQKEEQFNVLSSELEKLRENLTDMEAKFKEKDDREDQLVKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERSVEELQLKLTKANENASFLQKSIGEVTLKAEQSQQQAARKHEEEKKELEEKLLELEKKMETSYNQCQDLKAKYEKASSETKTKHEEILQNLQKMLADTEDKLKAAQEANRDLMQDMEELKTQADKAKAAQTAEDAMQIMEQMTKEKTETLASLEDTKQTNARLQNELDTLKENNLKTVEELNKSKELLSVENQKMEEFKKEIETLKQAAAQKSQQLSALQEENVKLAEELGRTRDEVTSHQKLEEERSVLNNQLLEMKKRESEFRKDADEEKASLQKSISLTSALLTEKDAELEKLRNEVTVLRGENATAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDAQAEEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGEDLNSYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSEDPPHSTHHGSRSEERPYCEICEMFGHWATNCNDDETF
What is the function of this protein?
Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton.  Promotes microtubule growth and microtubule bundling.  Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking.  Plays a role macropinocytosis and endosome trafficking.
What are the official names of this protein?
CAP-Gly domain-containing linker protein 1, Cytoplasmic linker protein 170, CLIP-170, Restin.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle. Note=Localizes to microtubule plus ends. Localizes preferentially to the ends of tyrosinated microtubules (PubMed:16954346). Accumulates in plasma membrane regions with ruffling and protrusions. Associates with the membranes of intermediate macropinocytic vesicles (By similarity).
Protein: NRDI_ECO8A
Sequence: MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIAQKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
What is the function of this protein?
Probably involved in ribonucleotide reductase function.
What are the official names of this protein?
Protein NrdI.
What is the protein family that this protein belongs to?
Belongs to the NrdI family.
Protein: GPMA_CORK4
Sequence: MSNGKLILLRHGQSQWNSTNQFTGWVDVDLTEKGEAEAKRGGELIKEKGLHPEVLYTSLLRRAIRTADIALNAADRLWIPVIRDWRLNERHYGALQGLNKADTKEKYGNEKFMAWRRSYDTRPPELEDGAEYSQSDDPRYANLDSVPKTECLKDVVARFVPYFKEEILPRAQKGQTVLIAAHGNSLRALVKHLDNISDDDIAGLNIPTGIPLVYEIAEDGSVVNPGGTYLDPEAAAAGAAAVANQGSK
What is the function of this protein?
Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
What are the official names of this protein?
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, BPG-dependent PGAM, PGAM, Phosphoglyceromutase, dPGM.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Protein: SYG_THEKO
Sequence: MGEKPDKYEILQDLMRRRGFAWGSFEIYGGSRGFYDYGPLGATIKRKIERKIREAFQREGFFELETPDITPEKVFIASGHVEKFVDPLVECKKCGARFRADHLVEEALGIDTEGMSAEHLTQLIREHDIRCPECGGELSDVWYFNLMFETRIGPYGDQKGYLRPETAQGIFVNFRRLNAFARNKLPFGVFQIGKAYRNEISPRQGMLRLREFTQAEAEIFFNPNETEHPHFDEVKDEKLRLYPIEHQLKNLSMIELTAEEAVKKGYIMNTFFAYYMVMVKRVLLDIGIPEDKIRFRQQLPEERAHYSRDTWDAEIHSERFGWVECVGIANRGDYDLSRHMRESGADLTVLIHYDEPKIVKKLEVSLNMKRVGPKLKKDAKRINELIKGWGEEKKRELVELLEKEGKVTIEGYELEKDDFIIREVEEKITGEKIVPHVLEPSFGIDRPFYLLLENSLVIEEDRTYLRIKKDMAPIEVAVLPLVAKEPLKSIAYDIFRTLQKEGFIAVYDEKDTVGRRYMRYDEIGTPYCVTVDNQTPEDGTVTIRDRDTREQIRVKIEELPKKLRELIFES
What is the function of this protein?
Catalyzes the attachment of glycine to tRNA(Gly).
What are the official names of this protein?
Glycine--tRNA ligase, Glycyl-tRNA synthetase, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH601_MYCBP
Sequence: MSKLIEYDETARRAMEVGMDKLADTVRVTLGPRGRHVVLAKAFGGPTVTNDGVTVAREIELEDPFEDLGAQLVKSVATKTNDVAGDGTTTATILAQALIKGGLRLVAAGVNPIALGVGIGKAADAVSEALLASATPVSGKTGIAQVATVSSRDEQIGDLVGEAMSKVGHDGVVSVEESSTLGTELEFTEGIGFDKGFLSAYFVTDFDNQQAVLEDALILLHQDKISSLPDLLPLLEKVAGTGKPLLIVAEDVEGEALATLVVNAIRKTLKAVAVKGPYFGDRRKAFLEDLAVVTGGQVVNPDAGMVLREVGLEVLGSARRVVVSKDDTVIVDGGGTAEAVANRAKHLRAEIDKSDSDWDREKLGERLAKLAGGVAVIKVGAATETALKERKESVEDAVAAAKAAVEEGIVPGGGASLIHQARKALTELRASLTGDEVLGVDVFSEALAAPLFWIAANAGLDGSVVVNKVSELPAGHGLNVNTLSYGDLAADGVIDPVKVTRSAVLNASSVARMVLTTETVVVDKPAKAEDHDHHHGHAH
What is the function of this protein?
Involved in copper homeostasis (PubMed:32812602).  Binds copper and may help maintaining copper homeostasis when copper is present in excess, notably in the macrophage phagosome, by acting as a metal storage protein (PubMed:32812602).  Increases copper tolerance during biofilm formation (PubMed:32812602).  In vitro binds to human CD209 (DC-SIGN) and may help mediate adherence to host cells (PubMed:21203928).
What are the official names of this protein?
Chaperonin GroEL 1, 60 kDa chaperonin 1, Chaperonin-60 1, Cpn60 1.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Although thought of as a cytoplasmic chaperone this protein has been found to interact in vitro with a host extracellular protein.
Protein: UBA4_DEBHA
Sequence: MNDLSREDLLQKIRLLELENAKLKESKSAVSTVSDQYEYDAKYPKIDEYFSSDEYKRYGRQMIVPQFGSLISQVKLKKSKVLFIGAGGLGCPALLYLSASGVGEIGIIDDDLVDISNLHRQVLHTTESVGIHKCESAKRYINKLNPHVKVNTYPFRLSNDNAFDIIEKYDLILDCTDTPATRYLINDVSVICGKTIVSGSGLKTDGQLSILNFHGIGPCYRCFYPKPPSPGSVTSCSDGGVVGPAIGLIGITMALEAIKVITDFYTDETFKPFLSMYSGYPQQQIRVFKMRNKQANCAVCGNNPTVLKSTISDNDIDYAEFCGRVNPNVLAPELRISVQEYHNYINSSQGENSILIDVRPKEQYEITKLPNSINIAWDPTFIKADNIDSYLPSNFDKNTNTFVMCRYGNDSQMATKKLIENFGFNEVKDIKGGINKWSKEIDSKIPQY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1.  Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase UBA4, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DPH2_EMENI
Sequence: MTTELAAAPVLSTPDDRILEETDPVVPQTNRILSEEELAITYDIERTLKEIRQARYKRIALQFPDEMLPDAPRVFQLLSRGLEARDIVDGGSKANTETEPTDGLVDSASRLDLKDADEWSPKLYILADTSYGTCCVDEVAAEHVDADVVVHYGRSCLSPTARLPVIYVFTHKELPLDPVLKAFKETYPDPETKVILAADVTYSDHIPEVYSRLVQEGYSSLFATALVHDPSSVIPNRTVPDSVKEAPESLGNWQLFHISEPPTALLLTLASRVAAIHIYPTDGPAGTDVKPLPASTAMVLRRRYAILTRLSTVPIFGILVNTLSVKNYLHIVDHVRDKIAAAGKKSYMFVVGKLNAAKVANFSEIGGWVVIGCWESSLVDSKDFWKPVITPFELEVALKGDEERVWTGAWQSDFQSILDQPPPSSNSPGNSQEANEGPEFGDHARDEDEDAMSEPESAPPEFDLRTGRYVSYSRPMRDSAPRVSASQGATAAISAQTGAADGPSAARALARRAKGDLAMVGNTFSPGAEFLRSQRTWTGLGSDFNSAANVEYDDEENDSTLVVQGRKGIARGYTVGDSIDRH
What is the function of this protein?
Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.  Dph1 and dph2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising dph3 and a NADH-dependent reductase, predominantly cbr1 (By similarity).  Facilitates the reduction of the catalytic iron-sulfur cluster found in the dph1 subunit (By similarity).
What are the official names of this protein?
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2, Diphthamide biosynthesis protein 2, Diphtheria toxin resistance protein 2, S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 2.
What is the protein family that this protein belongs to?
Belongs to the DPH1/DPH2 family. DPH2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS7_PROM2
Sequence: MSRRNAAVKRPVLPDPQFNSRLASMMISRLMKHGKKSTAQRILSDAFSLISERTGGNAVELFETAVKNATPLVEVRARRVGGATYQVPMEVRQERGTAMALRWLVTFSRARNGKSMSQKLAGELMDAANETGSAVKKREDTHKMAEANKAFAHYRY
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: PGLR2_ASPAW
Sequence: MHSFASLLRYGLAAGATLASASPIEARDSCTFTTAAAAKAGKAKCSTITLDSIKVPAGTTLDLTGLTSGTKVIFEGTTTFDYEDWAGPLISMSGKDITVTGASGHLINCDGSRWWDGKGTSGKKKPKFFYAHGLDSSSITGLNIKNTPLMAFSVESDDITLTDITINNADGDSLGGHNTDAFDVGNSVGVNIIKPWVHNQDDCLAINSGENIWFTGGTCIGGHGLSIGSVGDRSNNVVKNVTIEHSTVSNSENAVRIKTISGATGSVSEITYSNIVMSGISDYGVVIQQDYEDGKPTGKPTNGVTITDVKLESVTGTVDSKATDIYLLCGSGSCSDWTWDDVKVTGGKKSSACKNLPSVASC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase II, EPG-II, Pectinase 2, Polygalacturonase II, PG-II, Polygalacturonase X2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.