PharMolix/UniProtQA huggingface dataset:
Protein: QUEA_BACAN
Sequence: MDINLFDFHLPEELIAQVPLEERETSRLMVLDRETGDIEHKHFTDILSYLHEGDCLVLNETKVMPARLHGVKEDTGAHIEVLLLKQEEGDKWETLVKPAKRVKEGTVISFGEGKLKATCTGTADQGGRQLEFSYDGIFYEILDELGEMPLPPYIKETLEDRDRYQTVYAKEIGSAAAPTAGLHFTEELLEKLKQKGVELAFITLHVGLGTFRPVSADTIEEHHMHAEYYHMSEETAALLNRVKENGGRIITVGTTSTRTLETIATDHDGKLCAASGWTDIFMYPGYEFKAIDGLITNFHLPKSTLIMLVSAFANRDNVLHAYNEAVKEKYRFFSFGDAMFVASHAKMGNK
What is the function of this protein?
Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
What are the official names of this protein?
S-adenosylmethionine:tRNA ribosyltransferase-isomerase, Queuosine biosynthesis protein QueA.
What is the protein family that this protein belongs to?
Belongs to the QueA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_PSEU2
Sequence: MGALTKAEMAERLYEELGLNKREAKELVELFFEEIRHALEDNEQVKLSGFGNFDLRDKRQRPGRNPKTGEEIPITARRVVTFRPGQKLKARVEAYAGTKS
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: COX2_PHYHA
Sequence: MALPFQLGFQDATSPIMEELLHFHDHTLMIVFMISSLVLYLISSMLTTRLTHTSTMDAQEVETIWTILPAIILITIALPSLRILYMMDEINNPSMTIKTMGHQWYWSYEYTDYSELCFDSYMIPTSDLKSGGLRLLEVDNRVVIPMEMTVRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQTTLLSTRPGLYYGQCSEICGSNHSFMPIVLEMVTLNCFEKWSTSML
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: U73C5_ARATH
Sequence: MVSETTKSSPLHFVLFPFMAQGHMIPMVDIARLLAQRGVIITIVTTPHNAARFKNVLNRAIESGLPINLVQVKFPYLEAGLQEGQENIDSLDTMERMIPFFKAVNFLEEPVQKLIEEMNPRPSCLISDFCLPYTSKIAKKFNIPKILFHGMGCFCLLCMHVLRKNREILDNLKSDKELFTVPDFPDRVEFTRTQVPVETYVPAGDWKDIFDGMVEANETSYGVIVNSFQELEPAYAKDYKEVRSGKAWTIGPVSLCNKVGADKAERGNKSDIDQDECLKWLDSKKHGSVLYVCLGSICNLPLSQLKELGLGLEESQRPFIWVIRGWEKYKELVEWFSESGFEDRIQDRGLLIKGWSPQMLILSHPSVGGFLTHCGWNSTLEGITAGLPLLTWPLFADQFCNEKLVVEVLKAGVRSGVEQPMKWGEEEKIGVLVDKEGVKKAVEELMGESDDAKERRRRAKELGDSAHKAVEEGGSSHSNISFLLQDIMELAEPNN
What is the function of this protein?
Specifically catalyzes 23-O-glucosylation of brassinosteroids, resulting probably in their inactivation.  Also, involved in the O-glucosylation of trans-zeatin and dihydrozeatin.  Active in vitro on cis-zeatin, dihydrozeatin-9-N-Glc, and olomoucine.  Also involved in the detoxification of the Fusarium mycotoxin deoxynivalenol by the transfer of glucose from UDP-glucose to the hydroxyl group at C-3.  Possesses low quercetin 7-O-glucosyltransferase and 4'-O-glucosyltransferase activities in vitro.
What are the official names of this protein?
UDP-glycosyltransferase 73C5, Cytokinin-O-glucosyltransferase 3, Deoxynivalenol-glucosyl-transferase 1, Zeatin O-glucosyltransferase 3, AtZOG3.
What is the protein family that this protein belongs to?
Belongs to the UDP-glycosyltransferase family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: ATPD_ACICJ
Sequence: MSSAVSASPQAASPQQDRTSGLSARYARALYELADERKQLDEVVSEMAALGRLFAEDPSLRRLIASRSIDAREAGRAMEQVLASQGVSDLVRNFIGTAIANRRLADLPSLVAGFAVYVAEKRGVVAADIASAHPLTDTQRAQLTARLAEAGYGRVTIRETVDPSLLGGLTVRIGSKLYDTSLKSRLQRLRHVMKGAA
What is the function of this protein?
This protein is part of the stalk that links CF(0) to CF(1).  It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.
What are the official names of this protein?
ATP synthase subunit delta, ATP synthase F(1) sector subunit delta, F-type ATPase subunit delta, F-ATPase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the ATPase delta chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RL18A_MOUSE
Sequence: MKASGTLREYKVVGRCLPTPKCHTPPLYRMRIFAPNHVVAKSRFWYFVSQLKKMKKSSGEIVYCGQVFEKSPLRVKNFGIWLRYDSRSGTHNMYREYRDLTTAGAVTQCYRDMGARHRARAHSIQIMKVEEIAAGKCRRPAVKQFHDSKIKFPLPHRVLRRQHKPRFTTKRPNTFF
What is the function of this protein?
Component of the large ribosomal subunit (PubMed:36517592).  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:36517592).
What are the official names of this protein?
60S ribosomal protein L18a.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL20 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HYPA_METSB
Sequence: MHEISLIESVVALVEDERRKQDFSRVRMIRLRLGALGHAEPEALRFCFDAVTRGTIAEGARLDIDIVLGEGWCSSCSRTVPLEERFAACPICGNAPVQMTAGDELRVAEMEVE
What is the function of this protein?
Involved in the maturation of [NiFe] hydrogenases.  Required for nickel insertion into the metal center of the hydrogenase.
What are the official names of this protein?
Hydrogenase maturation factor HypA.
What is the protein family that this protein belongs to?
Belongs to the HypA/HybF family.
Protein: ACDH_ECOSM
Sequence: MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIASKSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
What is the function of this protein?
Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A.  Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
What are the official names of this protein?
Acetaldehyde dehydrogenase, Acetaldehyde dehydrogenase [acetylating].
What is the protein family that this protein belongs to?
Belongs to the acetaldehyde dehydrogenase family.
Protein: TGT_STRP4
Sequence: MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSIGGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIRLTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.
Protein: HSLU_RICCK
Sequence: MKATKITYKKDPMGLTPAQIVNELNRFIVGQEKAKKAVAIALRNRCRRKRVEGNLRNEIVPKNILMIGSTGVGKTEIARRLAKLTNSPFYKIEATKFTEVGYVGRDVESIIRDLVEIAVNTEKTLAKTEVDINAREKAIERILDSLVGKTSSSETREKFKEKVLNGELNDTEIEISVADTAPIGGGSFEIPGMPGSSMGVLNLGDMIGRALGSSKTKTKKMLVKEAMAIIIPEELEKLIDQEKIIQQAITLAENDGIVFIDEIDKIASAPSSGAKNAEISREGVQRDLLPLIEGTTVNTKYGQVKTDHILFIASGAFHIAKPSDLLPELQGRLPIRVELNSLTKDDMIKILLEPETSLIKQYSALIGTEDVHLEFTASAIEKIADYAITVNLEVEDIGARRLHTILENLLEDISFEASEMKGKKITIDDQFVENQLSKIITNLDLAKFIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MNMA_PARL1
Sequence: MTGLNSLDLPGRPEDTRVVVAMSGGVDSSVTAALLKEQGYDVVGITLQLYDHGAAVSRKGACCAGQDIQDARRVADQIGIPHYVLDYEDRFRRAVMDDFADSYAAGETPIPCVRCNERVKFRDLLDTARDLGAAALATGHYIASRRGAAGRELHRPRDEERDQSYFLFATTQEQLEFLRFPLGELTKPEARALADRMGLEVAGKPDSQDICFVPTGRYTTIVEKLRPGASAPGEVVHLDGRVLGRHSGIVNFTIGQRRGLGIGASEPVSEPLFVVKLDPLKRQVIVGPREALETQKLTLRDINWLGDGPFAELPGEGLKIVAKVRSTRPPVPARLFRTGEGAVVELLESEGGVAPGQACVFYDGGGGQRVLGGGWIVRTESCWQVPEAGTSRVAAPTAD
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TYPH_POLSJ
Sequence: MQTPPTPLSSLTPHKLRLRRLGIDTYQEPVLYMHRDCRVCHSEGFEAQSRVELALGDRTIVATLNVVSGDFLAPDEAGLSEAAWRLLGAQEGDMVSPRHPAPIESLGHVRAKVYGRHLTQAAITAVIEDVTAGRYSDLQLAAFVTACAGDRLDQEETVSLTRAMVAAGERIDWGEGLVMDKHCVGGLPGNRTTMVIVPIVAACGLRMPKTSSRAITSPAGTADTMETLAPVDLDVAQIRRVVERTGGCVVWGGAVRLSPADDILIRVERPLDLDSQGQLVASILSKKVAAGSTHVLIDMPVGPTAKVRSAEAADLLGRLLGQVGQTLGLRMRVVQTDGLAPVGRGIGPALEARDVLAVLRNLATAPADLAQRSLLLAGEVLEFGGAAPAGGGLALASAVLADGRAWRKFQDICAAQGGLREPPVAAHQQAVHALRSGSVLAIDNRRLARIAKLAGAPGAACAGIDLHVRPGEFVERGQPLFTLHAATPGELAYALEYAASQAETVHVLEDA
What are the official names of this protein?
Putative thymidine phosphorylase, TdRPase.
What is the protein family that this protein belongs to?
Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
Protein: GLYA_CAMJJ
Sequence: MSLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRYYGGCEFVDEIETLAIQRCKKLFNCKFANVQPNSGSQANQGVYAALINPGDKILGMDLSHGGHLTHGAKVSSSGKMYESCFYGVELDGRIDYEKVREIAKKEKPKLIVCGASAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGPRGGIIMTNDEEFAKKINSAIFPGIQGGPLMHVIAAKAVGFKFNLSDEWKIYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGITANKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYIADILDDINNEKLQENIKQELKKLASNFIIYERAMF
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: B3GN8_HUMAN
Sequence: MRCPKCLLCLSALLTLLGLKVYIEWTSESRLSKAYPSPRGTPPSPTPANPEPTLPANLSTRLGQTIPLPFAYWNQQQWRLGSLPSGDSTETGGCQAWGAAAATEIPDFASYPKDLRRFLLSAACRSFPQWLPGGGGSQVSSCSDTDVPYLLLAVKSEPGRFAERQAVRETWGSPAPGIRLLFLLGSPVGEAGPDLDSLVAWESRRYSDLLLWDFLDVPFNQTLKDLLLLAWLGRHCPTVSFVLRAQDDAFVHTPALLAHLRALPPASARSLYLGEVFTQAMPLRKPGGPFYVPESFFEGGYPAYASGGGYVIAGRLAPWLLRAAARVAPFPFEDVYTGLCIRALGLVPQAHPGFLTAWPADRTADHCAFRNLLLVRPLGPQASIRLWKQLQDPRLQC
What is the function of this protein?
Beta-1,3-N-acetylglucosaminyltransferase that plays a role in the elongation of specific branch structures of multiantennary N-glycans.  Has strong activity towards tetraantennary N-glycans and 2,6 triantennary glycans.
What are the official names of this protein?
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8, BGnT-8, Beta-1,3-Gn-T8, Beta-1,3-N-acetylglucosaminyltransferase 8, Beta3Gn-T8.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 31 family.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein: IF2_AERS4
Sequence: MAEVSVKQLATDIDTPVDRLLQQFVDAGISKSKADDLVSESEKQTLLAHLKKQHGGDELTAPARMTLQRKTKSTISVQGTGGKNKEVQVEVRKTRTYVKRSALEDEQRQAEAEETARLEAEEKARSEAENKVRLDAEEKARREAEQARREAEEKARIEAQSKARQAPQPAKAASSTAQQEAEKMAKREAEELKRQQEQTALQKAEELAAKKAEEARLMAEQNGPRWAEEEAARAKESSDYHLTTNKHAQAAEDELDRKEETSRRTAAAAVKAPKKAGRREDDRDSRNPRARKGKRGKMAMPNAMKHGFNKPAAVVNRDVVIGETITVAELANKMAVKGVEVIKAMMKMGAMATINQVIDQETAQLVAEEMGHKVVLRRENELEEAVLSDRDETSEAKSRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVETDSGMITFLDTPGHAAFTSMRARGAKSTDIVVLVVAADDGVMPQTIEAIQHAKAAEVPIVVAVNKIDKPEADPDRVKTELARYNVMSEDWGGDSQFVHVSAKSGEGIDDLLEAILIQSEVLELKAVVDGMASGVVIESFLDKGRGPVATVLVQEGTLRQGDIVLCGLEYGRIRAMRDELGREIKEAGPSLPVEILGLSGVPSAGDEATVVRDEKKAREVALYRQGKFRDVKLARQQKAKLENMFANMTEGEVSEVNVVIKADVQGSVQAICDALVQLSTDEVKVKIVGSGVGGITETDATLAAASSAILVGFNVRADASARKVIESESLDLRYYSVIYDLIDEVKQAMSGKLAPEYRQEIIGLAEVRSVFKSPKFGAVAGCMVTEGVVKRSNRIRVLRDNVVIYEGELESLRRFKDDVNEVRNGYECGIAVKNYNDVREGDQIEVYETIEIQRTL
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits.  Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.
What are the official names of this protein?
Translation initiation factor IF-2.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PRO_ADE40
Sequence: MGSSEQELVAIVRELGCGPYFLGTFDKRFPGFMAPHKLACAIVNTAGRETGGVHWLALAWNPKNRTCYLFDPFGFSDERLKQIYQFEYEGLLKRSALASTPDHCITLIKSTQTVQGPFSAACGLFCCMFLHAFVNWPTSPMERNPTMDLLTGVPNSMLQSPQVVPTLRHNQERLYRFLAQRSPYFQRHCERIKKATAFDQMKNNM
What is the function of this protein?
Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions.  Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors.  Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating.  Without maturation, the particle lacks infectivity and is unable to uncoat.  Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction.  Cleaves host cell cytoskeletal keratins K7 and K18.
What are the official names of this protein?
Protease, Adenain, Adenovirus protease, AVP, Adenovirus proteinase, Endoprotease.
What is the protein family that this protein belongs to?
Belongs to the peptidase C5 family.
What are the subcellular locations of this protein?
Virion. Host nucleus. Note=Present in about 10 copies per virion.
Protein: AFAGR_AGRCY
Sequence: ANDPQCLYGNVAAKF
What is the function of this protein?
Has antifungal activity against M. arachidicola with an IC(50) of 125 uM, but not against F. oxysporum.  Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase with an IC(50) of 60 uM.  Has mitogenic activity towards murine splenocytes.  Lacks antiproliferative activity towards HepG2 hepatoma cells.  Has antibacterial activity against the Gram-negative bacterium P. fluorescens.  No antibacterial activity against the Gram-positive bacteria B. subtilis, B. cereus, B. megaterium, M. phei and S. aureus, or against the Gram-negative bacteria E. aerogenes, E. coli, P. aeruginosa, P. fluorescens and P. vulgaris.
What are the official names of this protein?
Agrocybin.
Protein: GLPK_SOLM1
Sequence: MANYILSLDQGTTSSRAILFTREGDIKQIAQKEFTQIYPQPGWVEHNANEIFDTQSYVMRECLQFAGVDASDVAAIGITNQRETTVVWDKKTGAPIHNAIVWQDRRTAGFCDELKAKGLADVIRQKTGLVIDAYFSGTKVRWILDNVPGAREKADKGELLFGTIDSWLIWNLTKGAVHVTDESNASRTLLFNINTGAWDDELLAIIGVPAAMLPRVSKSSEVVGEIHPEFLGKALPIAGNAGDQQAATYGNACLKEGMAKNTYGTGCFMLMNTGKAPRPSNNNLLTTMAWATPSGRYFALEGSVFIAGAVVQWLRDGLGIIQSAPEVEQLALSVPDNGGVFLVPAFAGLGAPHWDQYARGAMVGITRGATKAHIARAALESIALQTLDIMDCMQKDAGIKLDTLRADGGATRNNLLMQFQADVLGVPVERPMVTETTALGAAYLAGLAVGFWKSEEEIAAMWQLDRRFEPNMAQSDRDKLLHDWQRAVARSKAWIEA
What is the function of this protein?
Key enzyme in the regulation of glycerol uptake and metabolism.  Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
What are the official names of this protein?
Glycerol kinase, ATP:glycerol 3-phosphotransferase, Glycerokinase, GK.
What is the protein family that this protein belongs to?
Belongs to the FGGY kinase family.
Protein: Y208_LISMO
Sequence: MIVTTSPNIEGKQIIEYKKIVFGEVITGVNFMKDIGAGLRNFFGGRSQGYEDELINAREEAIREMEQRAKDIGANAVIGVDIDYEVLGADNGMLMVTASGTAVVIEAQDY
What are the official names of this protein?
UPF0145 protein lmo0208.
What is the protein family that this protein belongs to?
Belongs to the UPF0145 family.
Protein: RUVC_NEIG1
Sequence: MSATVRILGIDPGSRVTGFGIIDVRGRDHFYVASGCIKTPADEPLFTADRIAVIVRHIGEVVAVYKPQQAAVEQVFVNVNPASTLMLGQARGAALAALVSHKLPVSFTEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRNHGLAAFTKLNPSGMQVKRGRFQ
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: ACP_VARPS
Sequence: MSDIEARVKKIIAEQLGVEESQVTNEKAFVADLGADSLDTVELVMALEDEFGIEIPDEDAEKITTVQNAVDYATKNQKA
What is the function of this protein?
Carrier of the growing fatty acid chain in fatty acid biosynthesis.
What are the official names of this protein?
Acyl carrier protein, ACP.
What is the protein family that this protein belongs to?
Belongs to the acyl carrier protein (ACP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMPA_ACTP2
Sequence: MEFSVKNGSVEKQRTACLVVGVYEPRRLSAAAEQLDKLSEGYISTLLRRGDLEGKAGQTLLLHNVPNVPADRVLLVGCGKERELTERQYKQIIQKMVQAVSETGSMEVVCFLTELHVKGRTSYWNVRFAIEAIQESLYSYNDFKSIKPEVRREFRRVIFNVANRKDLADAERALEHGKAISTGVAFAKNVANCPPNVCNPAYLAELAKGLAAEYDNIRTTVIDEAEMAALGMNAYLAVSRGSQNPAYLSVIEYKNHPNPDAKPIVLVGKGLTFDSGGISIKPSDSMDEMKYDMGGAASVYGTMKALAEMKLPLNVIGVLAGCENMPDGNAYRPGDILTTMNGLTVEVLNTDAEGRLVLCDTLTYVERFEPELVIDMATLTGACMIALGAHNSGLMSTSNVLANELLNAAEQADDKAWRLPLGEEYQEQLKSNFADLANIGGRLGGAITAGQFLSNFTKKYSWAHLDIAGTAWKSGAAKGATGRPVSLLSQFLINKANNQ
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: T2R30_PONPY
Sequence: MITFLPIIFSILIVVIFVIGNFANGFIALVNSIEWVKRQKISFADQILIALAVSRVGLLWALLLHWYATELNLAFYSVEVRITAYNVWAVTNHFSNWLATSLSMFYLLKIANFSNLIFLRIKRRVKSVILVILLGPLLFLVCHLFVINMNEIVWTKEYEGNLTWKIKLRNAVFLSNMTLTMLANFVPLTLTLISFLLLICSLCKHLKKMQLHGKGSQDPSTKVHIKALQTVTCFLLLCAIYFLSMIISVYNFGRLEKKPVFMFCQAITFSYPSTHAFILIWGNKKLKQIFLSVLWHVRYWVKDRSLRLHRFTRAALCKG
What is the function of this protein?
Receptor that may play a role in the perception of bitterness and is gustducin-linked.  May play a role in sensing the chemical composition of the gastrointestinal content.  The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
What are the official names of this protein?
Taste receptor type 2 member 30, Taste receptor type 2 member 47, T2R47.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor T2R family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PGKC_TRYBB
Sequence: MTLNEKKSINECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLTEGGSCVLMSHLGRPKGIPMAQAGKIRSTGGVPGFQQKATLKPVAKALSELLLRPVTFAPDCLNAADVVSKMSPGDVVLLENVRFYKEEGSKKAKDREAMAKILASYGDVYISDAFGTAHRDSATMTGIPKILGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNMLQRIDYLLIGGAMAYTFLKAQGYSIGKSKCEESKLEFARSLLKKAEDRKVQVILPIDHVCHTEFKAVDSPLITEDQNIPEGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIAKAMGRGTHEHGLMSIIGGGDSASAAELSGEAKRMSHVSTGGGASLELLEGKTLPGVTVLDEKSAVVSYASAGTGTLSNRWSSL
What are the official names of this protein?
Phosphoglycerate kinase, glycosomal, Phosphoglycerate kinase C.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate kinase family.
What are the subcellular locations of this protein?
Glycosome.
Protein: URED_OPITP
Sequence: MDFAGHLHLRAAPRAFGHTALTLQSFRAPFHLSKPYWDYDSRVLLVQVVNPTAGILAGDRIESEITVDAGAALLITTPSASRVFRMDAGVATCRQHFTVAAGAWLEVMPGPLVPHRGSDYRQSTIVELTRGAGGFFVDQLMPGRAAHGEAWAWRRLCLEFECRLDGRLLVRERVDQSGEELRALAELAGSGAAACFANAILIPGAEADEDWRAAVEGLHRDGAWVGVSALREAGWSIKVIAPDGAYLRETLRAIRAVLAEAFPRMRCDPRRL
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreD.
What is the protein family that this protein belongs to?
Belongs to the UreD family.
What are the subcellular locations of this protein?
Cytoplasm.