PharMolix/UniProtQA huggingface dataset:
Protein: ATPG_BORA1
Sequence: MPGIKEIRTKIKSVQNTRKITKAMEMVAASKMRKAQERMRAGRPYANKVREIAAHLMQANPEYNHPYLQQREIKAVGVVLVTTDKGLCGGLNTNISRLTLNRFKDFEAQNIQVRATAFGNKGLGLLTRIGTKLVSQETQLGDKPDLDRLLGAIKVQLDDYLEGRIDALYVATTRFVNTMKQEPVFLRLLPLASGLNDPFQSGLEHLESTTEVKSDYGWDYIYEPDAKSVIDDLLQRYVEGLLYQAVAENMASEQSARMVAMKAASDNAKKVIGELQLVYNKTRQAAITKEISEIVGGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RPOC_BAUCH
Sequence: MKDLFKLLKAQAKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVVEGGMTYLERNQILTEEQYLDALEEFGDEFDAKMGAEAIHHLLKNMDLEQECEQLREEIVDVSSETKRKKLTKRIKLLESFVHSGNKPEWMILNVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLSAPDIIVRNEKRMLQEAVDALLDNGRRGRVITSSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLEICGLATTIKAAKKMVEREEAVVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLVEGKAIQLHPLVCAAYNADFDGDQMAVHIPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDRVNSKGEGMILTGPKEAEKIYHAGIAELHARVKVRITEYEKIDDNELVEKKQIIDTTIGRAILWMIVPKGLPFDLVNQVLGKKSISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGSSVGIDDMVIPAHKAEIIDDAENEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMDNLSTEVVLNCHGKEELQVSFNNIFMMSDSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEEDCGTLSGIVMTPVIEGGDVKESLRERVLGRVTTENILQPGKTDILVKRNTLLNEQWCDILEEHSVDNIKVRSVVTCDADFGVCAYCYGRDLARGHLVNKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAAFRAAAESSIQVKNHGILCLVNAKFVINSANKIVITSRNAELKISDEFGRTKESYKVPYGAIMAKGDGANIISGETIANWDPHTMPVITEVNGFIRFTDMIEGQTIIRQTDELTGLSSIVILDTAERTSSGKDLRPALKIVDANQQDILIPGTDMPAQYFLPGKTIVQLEDGTKITSGDTLARLPQETSGTKDITGGLPRVADLFEARIPKEPAILAEASGIISFGKDTKGKRRLVISSLHSNDSYEEMIPKWRQLNVFEGERVERGDVISDGPESPHDILRLRGVHAVTRYIINEVQDVYRLQGVRINDKHIEVIVRQMLRKATIINAGGSDLLEGEQVEYSRIKIINRQLKSEGRQEITYVRDLLGITKASLATESFISAASFQETTRVLTEASVAGKRDDLRGLKENVIVGRLIPAGTGYAYHQERARYSKHREEALDMQQITAADEASANLAELLNSSLTNHKH
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta', RNAP subunit beta', RNA polymerase subunit beta', Transcriptase subunit beta'.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta' chain family.
Protein: CAPSD_CMVN
Sequence: MDKSESTSAGRNRRRRPRRGSRSASSSSDANFRVLSQQLSRLNKTLAAGRPTINHPTFVGSERCKPGYTFTSITLKPPKIDRGSYYGKRLLLPDSVTEYDKKLVSRIQIRVNPLPKFDSTVWVTVRKVPASSDLSVAAISAMFADGASPVLVHQYAASGVQANNKLLYDLSAMRADIGDMRKYAVLVYSKDDALETDELVLHVDVEHQRIPTSGVLPV
What is the function of this protein?
Capsid protein.  Probably binds RNA and plays a role in packaging (By similarity).
What are the official names of this protein?
Capsid protein, CP, Coat protein.
What is the protein family that this protein belongs to?
Belongs to the cucumovirus capsid protein family.
What are the subcellular locations of this protein?
Virion.
Protein: Y3435_DICDI
Sequence: MKYSIDDLIFSKDIDEDLYCQLCCNLMNESVSCPNGHCLCKGCFHKQIETVKSECPICCIPVTIQTLCKNIYLQKHINNLKVYCPNSFLNNDNNKLILDEKKGCKEILTIEQLKNGKHLKECKFTFVSCEYNEKCGKYRMNEIENHQDQCNYYPTKCFYCKNDFERMNLSNHLLLDCPLVIIGCRYKDGGCNETFPRHELSKHLALEDNHQQYISNIINGHQSLLKSTSKQLKQLRSSCEELETKLINNDYSFNGRWIIKQFSAHFDLFKENPFTNLIISPPIFLTPTKEFSLSLSADTVVNSVNCISVILSKQFQSSSTIKFSFEITNQSQTKSIKKEEKKKFSHLIGSSHSIEFPTSEIYNIHNKFIVNDQLIIKFNIKILSIQDEQQEIEESEENFNNTLITELEE
What is the function of this protein?
Probable adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases.
What are the official names of this protein?
TNF receptor-associated factor family protein DDB_G0273435/DDB_G0273505.
What is the protein family that this protein belongs to?
Belongs to the TNF receptor-associated factor family. A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ZN622_CHICK
Sequence: MATYTCITCRVAFKDADIQRAHYKTDWHRYNLKRKVADMPPVTAENFQERVLAQRAVAEERDKVTATYCTVCSKRFSTFNAYENHLKSKKHLELEKKAVQAVSKKVKILNEKNLEKGLAVESVDKDEMNAAIQQAIRAQPSSSPKKVPLPPSHASSSPVPMESAGLLQSKERTQKPPRLQWFEQQAKKLAKQEAEEEEDSEEGWEEMDSDEDLGSEEEMEGVEEEEEKQAEAESTCAIGAIPVTDCLFCSHHSRTLMKNVAHMTKVHSFFIPDIEYLVDLRGLIKYLGEKIGVGKICIWCNEKGKSFYSTEAVQAHMNDKSHCKLFTDGDAALEFADFYDFRSSYPDHKEGQDMEVPAELPSDRELEYDDDTMELIPPFRCKSWSSFFNEILQAAVWSVKNGGCY
What is the function of this protein?
Pre-60S-associated cytoplasmic factor involved in the cytoplasmic maturation of the 60S subunit.
What are the official names of this protein?
Cytoplasmic 60S subunit biogenesis factor ZNF622, Zinc finger protein 622, Zn-finger protein C47.
What is the protein family that this protein belongs to?
Belongs to the REI1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ULK2_MOUSE
Sequence: MEVVGDFEYCKRDLVGHGAFAVVFRGRHRQKTDWEVAIKSINKKNLSKSQILLGKEIKILKELQHENIVALYDVQELPNSVFLVMEYCNGGDLADYLQAKGTLSEDTIRVFLHQIAAAMRILHSKGIIHRDLKPQNILLSYANRRKSNVSGIRIKIADFGFARYLHSNTMAATLCGSPMYMAPEVIMSQHYDAKADLWSIGTVIYQCLVGKPPFQANSPQDLRMFYEKNRSLMPSIPRETSPYLANLLLGLLQRNQKDRMDFEAFFSHPFLEQVPVKKSCPVPVPVYSGPVPGSSCSSSPSCRFASPPSLPDMQHIQEENLSSPPLGPPNYLQVSKDSASNSSKNSSCDTDDFVLVPHNISSDHSYDMPMGTTARRASNEFFMCGGQCQPTVSPHSETAPIPVPTQVRNYQRIEQNLISTASSGTNPHGSPRSAVVRRSNTSPMGFLRVGSCSPVPGDTVQTGGRRLSTGSSRPYSPSPLVGTIPEQFSQCCCGHPQGHEARSRHSSGSPVPQTQAPQSLLLGARLQSAPTLTDIYQNKQKLRKQHSDPVCPSHAGAGYSYSPQPSRPGSLGTSPTKHTGSSPRNSDWFFKTPLPTIIGSPTKTTAPFKIPKTQASSNLLALVTRHGPAESQSKDGNDPRECSHCLSVQGSERHRSEQQQSKAVFGRSVSTGKLSEQQVKAPLGGHQGSTDSLNTERPMDVAPAGACGVMLALPAGTAASARAVLFTVGSPPHSATAPTCTHMVLRTRTTSVGSSSSGGSLCSASGRVCVGSPPGPGLGSSPPGAEGAPSLRYVPYGASPPSLEGLITFEAPELPEETLMEREHTDTLRHLNMMLMFTECVLDLTAVRGGNPELCTSAVSLYQIQESVVVDQISQLSKDWGRVEQLVLYMKAAQLLAASLHLAKAQVKSGKLSPSMAVKQVVKNLNERYKFCITMCKKLTEKLNRFFSDKQRFIDEINSVTAEKLIYNCAVEMVQSAALDEMFQQTEDIVYRYHKAALLLEGLSKILQDPTDVENVHKYKCSIERRLSALCCSTATV
What is the function of this protein?
Serine/threonine-protein kinase involved in autophagy in response to starvation.  Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes.  Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR.  Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1.  May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences.  Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration.  Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons.
What are the official names of this protein?
Serine/threonine-protein kinase ULK2, Serine/threonine-protein kinase Unc51.2, Unc-51-like kinase 2.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
What are the subcellular locations of this protein?
Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Localizes to pre-autophagosomal membrane.
Protein: COXX_CUPTR
Sequence: MVTATHPHSLGRLSRMRHLARQYAALTKPRVTQLAVFCAIIGMFLATPGMVPWPVLIGGAAGIWLLAGAAFAINCLVEQKIDALMRRTAWRPSATGEITTRQTLVFSAILGGAGMWLLHVYANDLTMWLTFATFLGYAVVYTILLKPATPQNIVIGGLSGAMPPALGWAAVAGEVPAEAWFLVLIIFTWTPPHFWALALYRRADYAKSGLPMLPVTHGERYTLLHILLYTLIMIAATLLPFVYGMSGYIYLAAALALGAGFLAYAWKLYRNYSDELAQRTFRFSILYLSLLFAALLVDHYFKFVPQV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LXR3_HYPJQ
Sequence: MKNGAFPHDNAAVPNVERVLPLFSLKGRTAIVSGAGAGIGLAVAQAFAEAGANVAIWYNSNKQAVTSAEDIAKTYGVKCKAYQVNVTSAEAVDKAITEIIKEFNGRLDVFVANSGITWTEGAFIDGSVESARNVMSVNVDGVMWCAKSAGAHFRRQKEEGTTIDGKPLDNFIAGSFIATASMSGSIVNVPQLQAVYNSSKAAVIHFCKSLAVEWTGFARVNTVSPGYIITEISNFVPPETKTLWKDKIVMGREGRVGELKGAYLYLASDASSYTTGLDMIVDGGYSLP
What is the function of this protein?
L-xylulose reductase involved in the catabolism of L-arabinose through an oxidoreductive pathway.  Catalyzes the NADPH-dependent reduction of L-xylulose.  Is also able to convert D-xylulose, D-ribulose, L-sorbose, and D-fructose to their corresponding polyols.
What are the official names of this protein?
L-xylulose reductase.
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Protein: RL10_MANSM
Sequence: MALNLQDKQAIVAEVNEAAKGALSAVIADSRGVTVDKMTELRKTAREAGVSMRVVRNTLLRRAVEGTEFECLTDTFTGPTLIAFSNEHPGAAARLFKEFAKANDKFEIKGAAFEGKIQDVDFLATLPTYDEAIARLMGTIKEAAAGKLVRTFAALRDKLQEAA
What is the function of this protein?
Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL10 family.
Protein: YAEH_ECOL5
Sequence: MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
What are the official names of this protein?
UPF0325 protein YaeH.
What is the protein family that this protein belongs to?
Belongs to the UPF0325 family.
Protein: PNP_PROM1
Sequence: MQGQTKSVSFDGREIKLTTGRFAPQAGGSVMIECGDTSVLVTATKSSGREGVDFLPLMCDYEERLYAAGRIPGSFMRREGRPPERATLISRLIDRPMRPLFPGWMRDDIQIVATCLSLDERVPADVLAVTGASMATLMAGIPFQGPMAAVRVGLLGDDFVLNPSYREIERGDLDLVVAGTPDGVVMVEAGANQLSEQDVIEAIDFGYEAITELINAQKEVLKESGIKQEMPKAPEIDDTISTYLDKNCTKSISEVLKNFDQTKEERDNKIEEIKISISAKIDGLKDDNAVKKSLSLNNKLLENSYKALTKKLMREQIIKEGKRVDGRELNEVRAIEADAAVLPNRVHGSALFQRGLTQVLSTATLGTPSDAQEMDDLNPNTDKTYIHHYNFPPYSVGETRPMRTPGRREVGHGALAERALIPVLPAKDTFPYVLRVVSEVLSSNGSTSMASVCGSTLALMDAGVPLKAPVGGAAMGLIKEGKEVRILTDIQGIEDFLGDMDFKVAGTEKGITALQMDMKITGLPIETIGEAINQALPARTHILGKMLDAIETPKDNLSPHAPRLLSFRIDPELIGTVIGPGGRTIKGITERTNTKIDIEDGGIVTIASHDGAAAEEAQRIIEGLTRKVHEGEIFPGSITRIIPIGAFVEILPGKEGMIHISQLSEARVEKVEDVVKVGDQVTVRVREIDNRGRINLTLRGVSQNGGMSNYPEPTPTPVAPLT
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y5837_DICDI
Sequence: MENTENKILDKRKEYEKEIYNKEIDQCDDNNINREINYLVYRWLNSQNGIDKNLVTSLFQDFNKNDLLPKKVNWLGQQENFTSNELNEKYKHIQSDHIKSIFSSYRDLAIQHGHFSKLPFQINTLLGDNAYSMIPKGFNDKKDNDNNGDNNLLNKEKIPDNNNNNNSSSSSSSNSNTNKKKIKVSYLYNRPQVVTPTALQPENTTNTTTTTTATTTTTTTTTTTNNTNVQTTPTNTTNTTLTTPPPQIPILPTTVPDIDIQQQQQQQQQQQQQTISKSKNEDINNNNNILSIQRNRYKSFTMMRFTENPFDFSIPIPVKLSGQEVISKSLKSTSQLPISFYSNFKNSLIVYGHKAPTYCLQFDKSGRLYFTGSDDHLVKVWSTYSGRLIATLRGHLGDITDMCTSFDNSLLATASNDNVIRIWNLNSNQYDSIASLTGHDPSVNNTITSISFLSNPTTRLLVSSDSFGQCKLWNLDKSNHVISLSLNDNGSQSTINTGNINDEQIDTEMITDAEVPILTATTITTAITTTATTATATIATTTTTTTPGKTNEITGTTMNKGGTLIVASVDSSLKIWSTLFNPPKLVNTLEGHPTTILALQYSHGSDAIVSGSYDGTVIIWRHSGGPKWDHVIFNIKNTQRPNQANSHPKKVARSKATFKNVIWSHDDRFIITTDYNMIRVWNSLDGSFHLEMAEHTSEVYVTSCHPFDSRLIMSSGYDSQVILWSIETGEIIKKFVLQEPGFQCQILDGCFSPDGQKFIVTNSTGKWFMFELGLGSDINNLKKLVPNEQYFLTDYHPLIRDANGNVLDELTQTPPHLMPRAMLVNYQGLPYPDHYNFTDQDAIYHLEPYKNTSNYKRDLKIQKEFERREVYTFNQGNPSNIPSHPIVIFVASEPKPQPKKIPKKPRRPWDQIEEEIIDDEIIFPSDPSDEDFNPSDASENSSEDEQQQQHQQQQQDDDDDDDDDEDYDSDGKKMSTRKKSKIKADKRKKRLLKQSKKFTRRNTSPSKFNEIMNTFDLPEDDDNNSNNNNRKAVSNKRLSNKQKKRYNLINDGEIEMDDDDQYLNDNILDSDDNDYEHRNRYDNDEFSGSESYNGSDGGGGGGDDDSDNSSDNSSENDSSANGSDSDYSGSKSNKNKRGDKSKRNKKGKKNVKNKKVQKRGRKKSSTSSSSSTSHNQNHLTASALKKLNDIRKKKEILPVCPKWLSITSTTSETFYSPQVGDFIFYFYQGHTKYLEKFPPNGIESNLDNKSIVNYILNNNNINNNNNNNNNNNNNNNNNNNNNNNGVDDQQINSDDDDSQKIIKKSYQECIIKNLNYFISPDGTHKVVITLLPVFDQQVPPQNQNDESNFYTVIYHVSDIPDYLVLASKVRKSMLTDWTVPNKRFRMFYPASGWYNGTIIEISDSDPLFPNSPWENIKVLWDDTEEEDRVNYWEIDEKFDDDQNPQKIKEIKDENENEKVIENNQQQQQQQPQQQPQQQPIQNNQQLSINNTNVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSLNGGLVDYSGNNNNNNNNNFNYNSNNNLSMSGILDYTNFNNNNNNFMNYNMYQGNYNGMMMNNNTSNYSYLDPNNSNMYMQTYPQNSTMQNQQQPQLNNIYYNSQLQPTNYNYTNNFNTNYSNFNNSSSNIMNYNTNNNFNSPPTATTSNTTTTTTTTTETSNNNNNNNNNNNNNNNNNNFKDNILRIKIQYVESIEDEKIENLKKEMKEFLENDEITDIYSEPVDLKLYPLYIRFVPHPMDISTIIKRLESSYYRSLDAIYFDAKLIMIDAYVYNKPNTMVAKNSKLVFHRISDILKEAANYTPSDILLQSGGSFDSFTLKSMAADKDDSQLDDEDDSMVSGVTNDDDDDDDNLANNNHGNNKSRNGDGLEGDISISDSEHDNSKTGKNITRSLLSPSEDEGGINVNRTPSKRGRKKANATTTTTTTTTTTSSTPSKRLITGRLTRSRSNQSNEESDDDGFIDDNNSSHQNGGKILDDSDNDDKNQNGTDNDYNDDDDDDDNDGDSTNKKRKSIKNQTEPITKRQRTNRLIFEDEDEDDNNQEEDEEDYQEKPKPKPRSKQTTPKVTTPRKRGRKKIDQSEEEEDEDQSDVNSNNNSDNESGGEDGYSGEDGSESESNNGGDIDDEEFLNLLEKPKSKPKGRGRPSFKNNNNNNNINNNVNLTPSKRGRGRPPKSN
What are the official names of this protein?
Bromodomain and WD repeat-containing DDB_G0285837.
Protein: ASSY_VARPS
Sequence: MSTILQNVPAGQKVGIAFSGGLDTSAALHWMKLKGAIPYAYTANLGQPDEPDYDEIPRKAMLYGAENARLIDCRAQLANEGIAALQAGAFHVTTAGVTYFNTTPLGRAVTGTMLVSAMKEDDVHIWGDGSTYKGNDIERFYRYGLLTNPNLKIYKPWLDQLFIDELGGRAEMSAFMTKAGFGYKMSAEKAYSTDSNMLGATHEAKDLENLDSGMQIVQPIMGVAFWKDEVEVKRETVSVRFEEGRPVALNGVEHANLVELILEANRIGGRHGLGMSDQIENRIIEAKSRGIYEAPGLALLFIAYERLVTGIHNEDTIEQYRDHGRKLGRLLYQGRWFDPQAIMLRETAQRWVARAVTGEVTIELRRGNDYSILNTVSPNLTYKPERLSMEKVAGAFTPLDRIGQLTMRNLDIVDTREKLAIYTRTGLLSPGQGTAVPRLSNDDETK
What are the official names of this protein?
Argininosuccinate synthase, Citrulline--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the argininosuccinate synthase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTNC_ECOLI
Sequence: MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLGDMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPLAAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVALSVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAAFTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD
What is the function of this protein?
Also functions as a receptor for bacterial chemotaxis and is required for infection of the cell by bacteriophage lambda where it most likely functions as a pore for penetration of lambda DNA.
What are the official names of this protein?
PTS system mannose-specific EIIC component, EII-P-Man, EIIC-Man, Mannose permease IIC component.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: WLS_DROWI
Sequence: MSGTILENLSGRKLSILVSILLLCQVLCFLLGGIFAPVPAGHLTILGSLCRENHARQNDTNFFLYSRGDGACKQVTSEEVDADALKLANQIVHVFQLPLPRENKILEYTRWQQNLIGVLQVEFGYDSSPELHEPAKELQLTIDMRLAYRNNDDADNDWKLYAHSVEHRYLDCDTSHIGPTETLYTCDMIPLFELGALHHSFYLLNLRFPLDSPKQMNLQFGHMHDLTLTAIHQNGGFTKVWLFLKSVLFPFVVGIMVWFWRRVHLLQRSPALLEYMLIYLGGALTFLNLPLEYLTLGLEMPYMLLLSDIRQGIFYAMLLSFWLIFAGEHMLIQDSGNKSTIRSRYWKHLSAVVVGCISLFIFDISERGVQLRNPFYSIWTTPLGAKVAMGFIFLAGVSAAIYFLFLCFMIWKVFKNIGDKRTSLPSMSQARRLHYEGLIYRFKFLMLATLLCAALTVAGFIMGQMAEGHWKWNEHIEIQLTSAFLTGVYGMWNIYIFALLILYAPSHKQWPSMHHSDETTQSNENIVASAASEEIEFSHLPSDSNPSEISSLTSFTRKVAFD
What is the function of this protein?
A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells.  In non-neuronal cells wls directs wg secretion.  The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26).  In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles.  Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip (By similarity).
What are the official names of this protein?
Protein wntless.
What is the protein family that this protein belongs to?
Belongs to the wntless family.
What are the subcellular locations of this protein?
Presynaptic cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Note=In non-neuronal cells, wls binds to wg in the Golgi and accompanies it to the plasma membrane where the two proteins dissociate. Wg is secreted and wls is then internalized and returns to the Golgi apparatus in a retromer-dependent manner. Wls and wg colocalize in the Golgi apparatus in wg-producing cells, and reduced expression is seen in non-producing cells. Endoplasmic reticulum expression is unchanged in wg-producing versus non-producing cells. In neuronal cells, wls is localized both pre- and postsynaptically and is transferred trans-synaptically from the pre- to the postsynaptic compartment (By similarity).
Protein: YBEY_STAA1
Sequence: MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTFVDKQEIQEINRTYRDKDKVTDVISFALEEDEPEIDFSGLDIPRVLGDIIICTDVAQEQANNYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX7_YEAST
Sequence: MANKVIQLQKIFQSSTKPLWWRHPRSALYLYPFYAIFAVAVVTPLLYIPNAIRGIKAKKA
What is the function of this protein?
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.  The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase.  Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water.  Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of COX2 and heme A of COX1 to the active site in COX1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)).  The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
What are the official names of this protein?
Cytochrome c oxidase subunit 7, mitochondrial, Cytochrome c oxidase polypeptide VII.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c oxidase VIIa family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PPM1L_BOVIN
Sequence: MIEDTMTLLSLLGRIMRYFLLRPETLFLLCISLALWSYFFHTDEVKTIVKSSRDAVKMVKGKVAEIMQNDRLGGLDVLEAEFSKTWEFKSHNVAVYSIQGRRDHMEDRFEVLMDLANKTHPSIFGIFDGHGGETAAEYVKSRLPEALKQHLQDYEKDKENSVLSYQTILEQQILSIDREMLEKLTVSYDEAGTTCLIALLSDKDLTVANVGDSRGVLCDKDGNAIPLSHDHKPYQLKERKRIKRAGGFISFNGSWRVQGILAMSRSLGDYPLKNLNVVIPDPDILTFDLDKLQPEFMILASDGLWDAFSNEEAVRFIKDRLDEPHFGAKSIVLQSFYRGCPDNITVMVVKFRNSSKTEEQ
What is the function of this protein?
Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
What are the official names of this protein?
Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon.
What is the protein family that this protein belongs to?
Belongs to the PP2C family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ATPA_SALAI
Sequence: MAELTISTEEIRGALERYVSSYTADVSREEVGTVADAGDGIAHVEGLPSTMTNELLEFEDGTLGVALNLDVREIGVVVLGDFGGIEEGQRVKRTGRVLSAPVGDAFLGRVVNALGHPIDGLGDIANEGFRELELQAPNVMARKSVDEPLQTGIKAVDAMTPIGRGQRQLIIGDRKTGKTTVALDTILNQRDNWRSGDPKKQVRCIYVAVGQKASTIASIKGVLEEAGAMEYTTIVASPASDPAGFKYLAPYTGSTIGQHWMYGGKHVLVVFDDLSKQAEAYRAVSLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDEMGGGSMTGLPIIETKANDISAFIPTNVISITDGQIFLETDLFNQGVRPAINVGTSVSRVGGAAQVKPMKKVAGSLRLNLAQYRELEAFAAFASDLDKASRAQLERGSRLVELLKQPNYSPFPVEEQVVSVWAGTEGRLDDIPVGEIRRFESEFLQYLRHKHEGVLAGIAAGTWGDEIIASLDAAISDFKNLFLGKEDEQRVNEPPAKPLAGEENRETVTRFRDGTTDRPAES
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: XERD_CAUVC
Sequence: MSQGEAWADAFLEMMAVERAAARNTLTAYGKDLEDARGFLSRSGHDLHDADAETIEAYFQDLGARGLSPATAARRRSAVRQFYRFVLGEGWRTDDPSRRVAAPKAGRPLPKVLERDEIERLLAAASAKDSAQGLRLACMIELIYASGLRISELLALPLLALARDPAYLIVKGKGGKERLAPLNDAARAAVKAYLVERPAFLPKGQKDSPWLFPSRGATGRLTPRRVGQLLEDAAIAAGIDRQKVSPHVLRHAFATHLLEGGADLRVIQTLLGHADIATTQIYTHVAGEHLAHIVQTKHPLGRKKG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerD.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RK32_TUPAK
Sequence: MAVPKKRTSKSKTNLRKTVWKKKALKQAIQAYFIASRASKKLNLEKAITKDLNTES
What are the official names of this protein?
50S ribosomal protein L32, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL32 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ZSWM7_HUMAN
Sequence: MAVVLPAVVEELLSEMAAAVQESARIPDEYLLSLKFLFGSSATQALDLVDRQSITLISSPSGRRVYQVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA
What is the function of this protein?
Involved in early stages of the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.  Required for meiotic progression, hence for fertility (PubMed:32719396, PubMed:33713115, PubMed:34402903).
What are the official names of this protein?
Zinc finger SWIM domain-containing protein 7, SWIM domain-containing and Srs2-interacting protein 1 homolog, SWIM-type zinc finger domain-containing protein 7.
What is the protein family that this protein belongs to?
Belongs to the SWS1 family.
What are the subcellular locations of this protein?
Nucleus.