PharMolix/UniProtQA huggingface dataset:
Protein: FBX10_ARATH
Sequence: MVSVNLPWELVEEILYRVPPQSLARFRTVCKQWNSLFDDNKFVNDHLVRSRPQFMFRTDSKMYSVAVNFSGPWIEVHELTLDIPGLNCEMPIWLYNYVDCDGLLFCTSYKFKGVLIWNPWLKQTRLFASNHHYPTKYVIGYDNKKRYKVLDYEFEPSSKLTIYEIGLYSKKVKDLESDSSWSVVQSNSVSLNGTLYWAGVDVNNGIFIRSFSFSTERLTTFCRLPLKYNEDNILALAVFRKDRFSLLKLCNKTSKIKIWLTKNSINNREIGLVEDVVWIKLMTVLIPDFPKLPFRWYNRPDLTYFLDNDDAKRLVICCYDETQQVYIYIVRRNIVKKIKIDLFEDLLDQSSPHLRTYIPSLVRPTQVKEDNNKLYVL
What are the official names of this protein?
Putative F-box only protein 10.
Protein: CPH2_CANAL
Sequence: MLSQYDEQLAAGDNNGFNKQGNATLYSFDFVDADDFLDSISGALPNNGHNNVNPNTNDISFEDMNIMNPNIYSPVSAASGDDFTQSSGQPMISEGSNYTGQNFTDYLSDNSLEGYDKNTSRPLHEVDIGFSNKRSNSTSTGSLSHNEEITPISHYSVDSIVTSPEPPINKQGDFPPIKRTTTVSSTNSITNTTKKPAKVTKPKSKDKNSHNMIEKKYRTNINTKILALRDAVPALRIAAGCDDVSIADLEGLTPASKLNKASVLTKATEYIKHLESKNFILKQQNIELHRLIQHANMNPKSLPPPPQQMQAPPQPGFGFYPPQNQSFNVTPASQYPSPQQQVSPTQQQTVHHPPQPNRYLLGGMAAVMGTSLFGGSGENDFRSLSALPFSYLFPNAILNPSPLTIQLWTLTKVLLVVGSLASIFIPMYKQAQLKKEDKPNTIPETSLLDWILISIGFKTPAKLSVSKRDAIISNLQGGNDWSQLVSDYFYLAGCEINFENCFLSLVLGTIIRHRFPVVATILNHYLSMKEALLLNLDYKGFSKSLIRLNQLISKVDGVSIFESTNLTTRLTNVFTNNRINANIVDGQNHVKYIEFYQRNINDYYAIVFNWRLLEFIHELNVTYLEQLNDDQSQVLTDLKIIEAFFGEQDNKLFGYYQLFTSILNANYAPYLFESLKDKVESSLEKFRIAYEGIDLTDHEIHNTSSEDEYEQESPVVYKYEPTLKSQKSLISSLNLVNEEEFIILTCSLTIYYYKNKEYDRALKLLNYLRLDNDSKTLSLLTFTSLITLINELIPGKIEDNVNLDSAIRICRDWLENPDLTQYMDEDIKLELKKIVVTKGMIVNGIDVNESDEE
What is the function of this protein?
Transcription factor that positively controls filamentous growth, virulence, and invasiveness.  Binds directly to the two SRE-1-like elements upstream of TEC1 and thus regulates positively expression of this important hyphal growth regulator.  Functions independently of known signaling cascades involving EFG1.  Regulates also gene expression during intestinal colonization but is not involved in host cell adhesion.
What are the official names of this protein?
Transcription factor CPH2, Candida pseudohyphal regulator 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: SODM_MYCPH
Sequence: SHSKHHATYVKGVNDAIAKLEEARANGDHGAIFLHEKNLAFHLGGHVNHTIWWKNLSPHGGDKPTGDLAAAIDDQFGSFDNFRAQFTAAANGLQGSGWAVLGYDTLGDRLLTFQLYDQQANVPLGIIPLLLVDMWEHA
What is the function of this protein?
Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
What are the official names of this protein?
Superoxide dismutase [Mn].
What is the protein family that this protein belongs to?
Belongs to the iron/manganese superoxide dismutase family.
Protein: BCDO2_MOUSE
Sequence: MLGPKQSLPCIAPLLTTAEETLSAVSARVRGHIPEWLNGYLLRVGPGKFEFGKDRYNHWFDGMALLHQFRMERGTVTYKSKFLQSDTYKANSAGGRIVISEFGTLALPDPCKSIFERFMSRFEPPTMTDNTNVNFVQYKGDYYMSTETNFMNKVDIEMLERTEKVDWSKFIAVNGATAHPHYDPDGTAYNMGNSYGPRGSCYNIIRVPPKKKEPGETIHGAQVLCSIASTEKMKPSYYHSFGMTKNYIIFVEQPVKMKLWKIITSKIRGKPFADGISWEPQYNTRFHVVDKHTGQLLPGMYYSMPFLTYHQINAFEDQGCIVIDLCCQDDGRSLDLYQLQNLRKAGEGLDQVYELKAKSFPRRFVLPLDVSVDAAEGKNLSPLSYSSASAVKQGDGEIWCSPENLHHEDLEEEGGIEFPQINYGRFNGKKYSFFYGCGFRHLVGDSLIKVDVTNKTLRVWREEGFYPSEPVFVPVPGADEEDSGVILSVVITPNQSESNFLLVLDAKSFTELGRAEVPVQMPYGFHGTFVPI
What is the function of this protein?
Broad specificity mitochondrial dioxygenase that mediates the asymmetric oxidative cleavage of carotenoids (PubMed:11278918, PubMed:21106934).  Cleaves carotenes (pure hydrocarbon carotenoids) such as all-trans-beta-carotene and lycopene as well as xanthophylls (oxygenated carotenoids) such as zeaxanthin, lutein and beta-cryptoxanthin at both the 9,10 and the 9',10' carbon-carbon double bond (PubMed:11278918, PubMed:21106934).  Through its function in carotenoids metabolism regulates oxidative stress and the production of important signaling molecules (PubMed:21106934).
What are the official names of this protein?
Carotenoid-cleaving dioxygenase, mitochondrial, B-diox-II, Beta,beta-carotene 9',10'-oxygenase, Beta-carotene dioxygenase 2.
What is the protein family that this protein belongs to?
Belongs to the carotenoid oxygenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: YR188_MIMIV
Sequence: MRSSFSKCKVNTCNPSNCLEVDILIVGGGASGIYSAWRLSQTYPNKKVLVIEEKSYLGGRLESVYFGNEKIYAEVGGMRTFPSIDLYVTAVIKKLKLQSIPVPYIEPDNIAYVKNTRLTVEATSIGPSSNPEKQKLIQLYKIPPDEQNISTNDIIYAAAVRAAPTFPEDWRTVYDYPELNNETFSEMFSEQGVSANTQQVFEVFSGYSFFISQRLAASTGIRENISISGENNQHFVVGGYSSIVFGMTDETFCNPNYQLFLNTSIKKITPSNSPNGLHTSILVDTLTGLPITIKSESIILSVPKDSLNRIVAPITPNTIETMNSLTDWRAFKAFLLVDQTTYQLISMNGHMKGRGISDLPARQVWAYSGNPPCVLIYCDNAYADFWKKYINDEINNCFPKFHDPCINKPLVSELKRQIGIIYSVDPSKIVVNKILYKYWYAGAYFSKPSDIPKLFEEVRTPLGPEYSVYLVGSDISVSQGWVDGALNTADNLLVKYYGVTSILDENRLY
What are the official names of this protein?
Uncharacterized protein R188.
What are the subcellular locations of this protein?
Virion.
Protein: ISPG_SHEFN
Sequence: MYNESPIIRRPSTRIYVGNVPIGDGAPIAVQSMTNTKTTDVAATVAQIRALEKVGADIVRVSVPTMDDAEAFKIIKQSVNVPLVADIHFDYRIALKVAEYGADCLRINPGNIGNEERIRSVVECARDKNIPIRIGVNGGSLEKDLMDKYREPTPEALFESAMRHVDILDRLNFDQFKVSVKASDVFLAVASYRLLAKQIRQPLHLGITEAGGMRAGSVKSAVGLGMLLAEGIGDTLRISLAADPVEEIKVGFDILKSLRIRSRGINFIACPSCSRQEFDVISTVNELERRLEDITTAMDVSIIGCVVNGPGEALVSDIGLTGGHAKSGYYDDGVRQKERFDNNKIIDGLEAKIRAKASMMANRIAITDKTE
What is the function of this protein?
Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin), 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the IspG family.
Protein: DNLJ_BACAN
Sequence: MSKEIAKKRIEELRDLLNTFNYQYHVLDNPSVSDAEYDRNMQELIKLEAENPEFMSEDSPSIRVGGTVLDIFEKVTHKSPMLSLGNAFNEGDLRDFDRRVRQGIDDANVRYICELKIDGLAVSLHYEKGRFIQGATRGDGVTGEDITQNLKTIKAIPLRLNEEVTLEARGEAYMPKRSFVKLNEEKEQNGEDVFANPRNAAAGSIRQLDPKIAAKRNLSMFVYGLANVEEKTIPSHSESLDYLGELGFKTNPNRRTCETIEEVIAYVEEWQEKRPHLDYEIDGIVIKVDDVALQESLGTTAKSPRWAIAYKFPAEEVVTRLTGIELSVGRTGVVTPTAELEPVRVAGTIVRRASLHNEDLIREKDIRIGDYVVVKKAGDIIPEVVNVIFDKRTGGEEEYHMPTHCPACESELVRLEEEVALRCINPTCPAQIREGLIHFVSRNAMNIDGLGERVITQLFDADYIRTFADLYSLTKEQLLQLERFGEKSATNLVQAIENSKENSLERLLFGLGIRHVGAKAARTFAEHFETMDALVKATEEELKAINEIGEKMAQSVVAYFDNEDVLELLQQFKEYGVNMTYKGIKIADLQNVESYFAGKTVVLTGKLEVMGRSEAKKKIEALGGKVTGSVSKSTDLVVAGEAAGSKLAQAEKHNVEVWNEERFLQELNK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: SWC4_SCHPO
Sequence: MTSADIRDVFELPPPEIGNKQKSKTPTERRPEGISRELYSLLGENSAPLAIYQKKFKEKPKVSHKAKNWVRQPFSISSRKDDFTLHHWVLKSEVDSEASYKFEKFNVPLFIIDYTDEEYQNYLKDEDWNKDETDYLFRLCKDYDLRFFVIADRYDNEKYKKHRTLEDLKDRFYSVSRKILLARNPINSMTAAQSSLLNTMEYNKEQEVIRKKYLIGLASRTPEEVAEEEALFIELKRIETSQAKLLSDRDEVLRLLDEQKGDGGIHEYHTSAGMSSLIQDMINSQRTKNKVEEAIVSSSAPSSGVSSVLNTPTRPHALSTPRIRYGPQPTDPQFGITWHEKLHPGTFVRSQKIPAIKASLSQRVSSVMTELGVSSRLIMPTAKNFEKFVELQNSIVSLLELKRKVDRLSQETEIQDKLSRKRSASPDGSESKKHISQ
What is the function of this protein?
Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling.  Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A.  The NuA4 complex is also involved in DNA repair (By similarity).
What are the official names of this protein?
SWR1-complex protein 4.
What is the protein family that this protein belongs to?
Belongs to the SWC4 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DRAM1_HUMAN
Sequence: MLCFLRGMAFVPFLLVTWSSAAFIISYVVAVLSGHVNPFLPYISDTGTTPPESGIFGFMINFSAFLGAATMYTRYKIVQKQNQTCYFSTPVFNLVSLVLGLVGCFGMGIVANFQELAVPVVHDGGALLAFVCGVVYTLLQSIISYKSCPQWNSLSTCHIRMVISAVSCAAVIPMIVCASLISITKLEWNPREKDYVYHVVSAICEWTVAFGFIFYFLTFIQDFQSVTLRISTEINGDI
What is the function of this protein?
Lysosomal modulator of autophagy that plays a central role in p53/TP53-mediated apoptosis.  Not involved in p73/TP73-mediated autophagy.
What are the official names of this protein?
DNA damage-regulated autophagy modulator protein 1, Damage-regulated autophagy modulator.
What is the protein family that this protein belongs to?
Belongs to the DRAM/TMEM150 family.
What are the subcellular locations of this protein?
Lysosome membrane; Multi-pass membrane protein.
Protein: RS10_PARUW
Sequence: MAKQEKQPKSARQKIRIRLKGYDQRLLDRSTGDIVETAKRTGAAIAGPIPLPTSCEKFTVLRSPNIDRKSREQFEIRTHRRLIDILNPTSKTIDALKTLTLPAGVDIKIKA
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: RNY_STAA9
Sequence: MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVNQAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSDLLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQRVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDGRIHPGRIEDMVEKARKEVDYIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQNVLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKYGENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETLSESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTVVRETRAVEYAK
What is the function of this protein?
Endoribonuclease that initiates mRNA decay.
What are the official names of this protein?
Ribonuclease Y, RNase Y, Conserved virulence factor A.
What is the protein family that this protein belongs to?
Belongs to the RNase Y family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: ACDA_METJA
Sequence: MVMGNNVEMDIKKLLTPLVKMKNANISMSIKFGEEEEEEWEPMGPTPMPKIPTLRHWDFKLLERYPPFYMPICDLCCLCTFGKCDLSRGKKGACGLNIKAQQARIVLIACCIGAACHAGHSRHLVHHLIETLGRDYPIDLGNEIEVEAPIARTVTGIKPKTLGDLEKILDYCEEQITHLLSAAHTGQEGDYLDFESKALHAGMIDDLAREAGDLAQIVAYNMPKGDEDAPLIELGFGCIDKSKPVILCIGHNVVPGSYILEYLEENSMEDEVEVCGICCTAIDITRVSDKPKVVGPLSRQLMFVRSGVADVVIVDEQCIRTDILEEVLKTGAVLIATNEKMCLGLEDVSHMDEDEIIGYLLRNRAALLLDEKKVGKVAVEVAKIVAKERKDRKTLPDLNEVVELAKQCTECGWCNRNCPNAFKVKEAMALAKQGNFKGFIDLYKRCYGCGRCEAICPRNLPIVSMTTKVGEAYYKDLKFKMRAGRGPIKDVEIRSVGAPIVFGDIPGVVALVGCSNHPNGEEEVAMIAKEFLERKYIVVATGCAAMAIGMWKDKDGKTLYEKYPGEFRAGGLVNCGSCLSNCHITGAAIKIANIFAKVPLRGNYAEVADYILNKVGAVGVAWGAMSQKAAAIATGVNRWGIPVILGPHGAKYRRLYLSNGEKFKVKDKKTGEILEIEPAPEHLIVTAENVKECICMIPKLCMRPNDTPKGRANKIYHYVDVYEKYFGRMPPDLEKFVRTEKDIPFMMKDKIMAYLEEKGWKPLEKYPQDPTILY
What is the function of this protein?
Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2).  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit alpha, ACDS complex subunit alpha, ACDS complex carbon monoxide dehydrogenase subunit alpha, ACDS CODH subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the Ni-containing carbon monoxide dehydrogenase family.
Protein: RS18_CAMJE
Sequence: MAEKRKYSRKYCKYTEAKVEFIDYKDTAMLKHALSERFKIMPRRLTGTSKKYQEMVEVAIKRARHVALIPYIVDRKEVINNPFEGL
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
Protein: ISCR_SHIDS
Sequence: MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKLRA
What is the function of this protein?
Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins.
What are the official names of this protein?
HTH-type transcriptional regulator IscR.
Protein: TRPA_BRUC2
Sequence: MTTRIDTKFAELKAEGRPALVTYFMGGDPDLETALKVMKALPKAGADVIELGMPFSDPMADGPAIQAAGLRALNAGQTLAKTLYMAAEFRKEDDTTPIVMMGYYNPIYVYGVERFLTDAKASGVDGLIVVDLPSEMDAELCIPAMKAGINFIRLTTPTTDDKRLPKVLHNSSGFVYYVSMNGITGAAIADTAKVGEAVRHIKKSTDLPICVGFGVKTPEQAAAIATHADGVVVGTAIVNAIAGELDEKGKVKGDPVAAATRLVHALAESVRATRLEAAQ
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: T2F7_NEIGO
Sequence: MNTVFSNIANAKITEKSLNAVWMDLFKSADEVLMATGYVSNDAVVELHKILELNDHIQKIDLLVGMHYLEGFSHLQYDSLCKLNDFLRHEKRGAVYVSPFVKFHGKMYSFKNYQKINGLIGSANLTCFWDSTERTYETMLHLNGKPAQILQADIQSTIHKLGKNIQEVERPSKFIEHNSHLENCLGVQKIAPEQIRQLFAQTSEYHFSIPAKTEEKSNLNVFFGEGRRDKRGFVKPRPWYEVELIVSKDITSQEGYPVLKSFTVITDDGWQFQCKTSGDYSKTSTQKMNLKTLGKWIKGRLESHGCLQNNEKITHETLREYGNESF
What is the function of this protein?
A P subtype restriction enzyme that recognizes the double-stranded sequence 5'-GCSGC-3'; the cleavage site is unknown.
What are the official names of this protein?
Type II restriction enzyme NgoFVII, R.NgoFVII, Endonuclease NgoFVII, R.NgoVII, S.NgoVII, Type-2 restriction enzyme NgoFVII.
Protein: NFI_XANOM
Sequence: MAMHTNGPVFAGWDGSVIQAQQLQQQLAQRVLLHDEVSATPQLLAGFDVGFEDDGQSTRAAAVLLDAHTLLPLETHVARVPTSMPYVPGLLSFRELPALLQALALLSRTPDLVFIDGQGIAHPRRLGIAAHFGVVTGLPCIGIAKQRLAGSFAEPGPERGDHTPILLGGAQIGWALRSKPRCNPLIVSPGHRVSMQGALGWNLRTLRSYRLPEPTRLADRLASRRGKMPALAADTPLLF
What is the function of this protein?
DNA repair enzyme involved in the repair of deaminated bases.  Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
What are the official names of this protein?
Endonuclease V, Deoxyinosine 3'endonuclease, Deoxyribonuclease V, DNase V.
What is the protein family that this protein belongs to?
Belongs to the endonuclease V family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYM_CERS5
Sequence: MARILITSAIPYINGIKHLGNLVGSQLPADLYARYMRGRGHEVMFICATDEHGTPAELAAAKAGKPVEVYCAEMHEIQKEIAAGFRLSFDHFGRSSSARNHRLTQHFAGQLAENGFIEEVSERQVFSVADNRFLPDRYIEGTCPNCGYDKARGDQCENCTKQLDPTDLINPRSAISGSTDLEVRETKHLYLRQRALKDEIEAWIDSKTDWPVLTTSIAKKWLHDGEGLQDRGITRDLHWGVPVKKGDQPWPGMEGKVFYVWFDAPIEYIAGTAEWADANGKTEADWERWWRTDKGAGDVRYVQFMGKDNVPFHTLSFPATIMGSREPWKLVDYIKSFNYLNYDGGQFSTSQGRGVFMDQALSILPADYWRWWLLSHAPENSDSEFTWENFQASVNKDLADVLGNLVSRVTKFCRSKFGETVPAGGAFGEREHQLIAELQERLAAYESCMEAMEIRKAATELRALWVAGNEYLQSAAPWTVVKTDPERAQAMIRLSLNLIRLYAVISRPFIPDAAASTMASLGCDDWSWPTDVAAALERLPAGHAFTTPDVLFRKITDEERAEWQTRFAGVRT
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPD_PSEPK
Sequence: MSNLRRAAEALRRSKTVVFFTGAGISADSGIPTFRDKLTGLWAKHDPQRLETADAFRANPTLVWSWYLWRRHQVSQAKPNSAHLSIPQLADAGWDVSVVTQNIDDLHERAGSSPVVHLHGSLMDVKCFGCHRPAELSPDQLAVPLEGQLIEPPRCTRCNGRLRPGVVWFRENLPDNAWRSAVRLVRACDLLVSVGTSGVVMPAAGIPDMALAVGATVIHVNLEDVGMDGADEIMLEGPAGVVLPALLQATGVAALSPPGVPT
What is the function of this protein?
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins.  Modulates the activities of several proteins which are inactive in their acylated form.
What are the official names of this protein?
NAD-dependent protein deacylase, Regulatory protein SIR2 homolog.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family. Class III subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MSCL_OCEIH
Sequence: MWKEFKEFAFKGNIIDLAVAVVIGGAFGAIVTSFVENIITPLMGVIVGGVDFTTLKVTVGEAEILYGNFIQSFVDFIIIAFSIFLAIKFLVKFKRQKEEEEVEAVVEELSKQEELLTEIRDLLKEQSNKN
What is the function of this protein?
Channel that opens in response to stretch forces in the membrane lipid bilayer.  May participate in the regulation of osmotic pressure changes within the cell.
What are the official names of this protein?
Large-conductance mechanosensitive channel.
What is the protein family that this protein belongs to?
Belongs to the MscL family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RR18_ARAHI
Sequence: MNKSKRPFTKSKRSFRRRLPPIQSGDRIDYRNMSLISRFISEQGKILSRRVNRVTLKQQRLITMAIKQARILSLLPFLNNQKQFERSESTPRTTSLRTRKK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: Y1663_STAAN
Sequence: MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDEFRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQIIVKPLDEIYAD
What are the official names of this protein?
UPF0342 protein SA1663.
What is the protein family that this protein belongs to?
Belongs to the UPF0342 family.
Protein: GUN_PSEFS
Sequence: MSPLKCMALAALGAVMFVGSAQAQTCDWPLWQNYAKRFVQDDGRVLNSSMKPTESSSEGQSYAMFFALVGNDRASFDKLWTWTKANMSGADIGQNLPGWLWGKKADNTWGVIDPNSASDADLWMAYALLEAARVWNAPQYRADAQLLLANVERNLIVRVPGLGKMLLPGPVGYVHAGGLWRFNPSYQVLAQLRRFHKERPNAGWNEVADSNAKMLADTASNPHGLAANWVGYRATSANTGLFVVDPFSDDLGSYDAIRTYMWAGMTAKGDPLAAPMLKSLGGMTRATAASATGYPPEKIHVLTGEVEKNNGYTPMGFSASTVAFFQARGETALAQLQKAKVDDALAKALAPSAPDTAQPIYYDYMLSLFSQGFADQKYRFEQDGTVKLSWEAACAVTR
What is the function of this protein?
Hydrolyzes carboxymethylcellulose.
What are the official names of this protein?
Endoglucanase, Carboxymethylcellulase, CMCase, Cellulase, Endo-1,4-beta-glucanase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 8 (cellulase D) family.
What are the subcellular locations of this protein?
Secreted.
Protein: RNH2_SALDC
Sequence: MIEFVYPHTHLVAGVDEVGRGPLVGAVVTAAVILDPARPIVGLNDSKKLSEKRRLSLYDEIKEKALSWSLGRAEAHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPELPVPSMAVVKGDSRVAEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAQYGATAHHRRSFAPVKRALGLVS
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease HII, RNase HII.
What is the protein family that this protein belongs to?
Belongs to the RNase HII family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UPPP_CORGB
Sequence: MNEEITLLAAAADPAATENIGWVQTIVLSIVQGLTEFLPISSSGHLRIISELFWGADAGASFTAVVQLGTEAAVLVFFAKEIWQIITGWFAGVFNKERRGFEYRMGWMIIVATIPVVILGVLGKDLIREALRNMWITASVLILFSLVFILAEKMGKKERDYDKLTMKDAIIMGLAQCLALIPGVSRSGGTISAGLFLGLKREVATKFSFLLAIPAVLGSGLYSLPDAFAPSSGQAASGLQLTVGTLFAFVVGYISIAWLMKFVANHSFSWFAAYRIPAGLLVMLLLALGMLNP
What is the function of this protein?
Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).  Confers resistance to bacitracin.
What are the official names of this protein?
Undecaprenyl-diphosphatase, Bacitracin resistance protein, Undecaprenyl pyrophosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the UppP family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DXR_RHOP5
Sequence: MSAVPLRNGKAAASGVRQVTVLGATGSIGDSTMDLLRATPERYQVEALTANSNVAGLAKLAIEFNARFAAVADASLLGDLRAALAGTGIECGAGEGAVIEAAARPSDWVMAAVAGAAGLKPALAAVDRGATVALANKECLVCAGEFFMQRAADAQACILPADSEHNALFQALASGDRAELTKVIITASGGPFRTWAAADIEQATLAQALKHPNWSMGQKITIDSASMMNKGLEVIEAHWLFALSPDEIEVVVHPQSIIHGMVEFSDRSVVAQLGAPDMRIPIAHCLGWPDRIVGRAAALDLTKIGQLTFEAPDFARFPGLRLAYDALRAGHCATTVYNAANEIAVAAFVKEQIRFGAIARLVEETLNAWIRAGNLAPLGSADDAISVDHKARNLAATLLPQIAAKAS
What is the function of this protein?
Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
What are the official names of this protein?
1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXP reductoisomerase, 1-deoxyxylulose-5-phosphate reductoisomerase, 2-C-methyl-D-erythritol 4-phosphate synthase.
What is the protein family that this protein belongs to?
Belongs to the DXR family.
Protein: TM114_HUMAN
Sequence: MRVHLGGLAGAAALTGALSFVLLAAAIGTDFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSHSGLWRTCRVQSPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQVDISFGWSLALGWISFIAELLTGAAFLAAARELSLRRRQDQAI
What are the official names of this protein?
Transmembrane protein 114.
What is the protein family that this protein belongs to?
Belongs to the PMP-22/EMP/MP20 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNT_MOUSE
Sequence: MSIETLLEAARFLEWQAQQQQRAREEQERLRLEREREREQEQKRASNLARLAHALPVEEPRIEAPPLPLSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQSLPPPPPLPPAAQPLPLAPRQPALVSTPGLSIKEPVTLPTRPQVPTPAPLLPDAKTTVAPTGSPKPLQPLPAPILTIAPHPGVQPQLAPQQPPPPTLGTLKLAPAEEAKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVDDKKTSNLSVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQTGQPEDDQASTSTASEGEDNVDEEMEGDRAGLGPPKLNHRPQPELLKSALPTPSTAPAPLPTHPHPHPHPVALSPAHLPVQQQQPPQQKTPLPAPPPPPATPTQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQTVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPPIGHITVHPATLNHVAHLGSQLPLYPQPVAVSQPVAVSHIAHTLSHQQVNGTAGLGPPATVMAKPAVGAQVVHHPQLVGQTVLNPVTMVTMPSFPVSTLKLA
What is the function of this protein?
Binds DNA as a heterodimer with MAX and represses transcription.  Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.
What are the official names of this protein?
Max-binding protein MNT, Myc antagonist MNT, Protein ROX.
What are the subcellular locations of this protein?
Nucleus.
Protein: Y2345_MYCTO
Sequence: MRLVRLLGMVLTILAAGLLLGPPAGAQPPFRLSNYVTDNAGVLTSSGRTAVTAAVDRLYADRRIRLWVVYVENFSGQSALNWAQRTTRTSELGNYDALLAVATTGREYAFLVPSAMPGVSEGQVDNVRRYQIEPALHDGDYSGAAVAAANGLNRSPSSSSRVVLLVTVGIIVIVVAVLLVVMRHRNRRRRADELAAARRVDPTNVMALAAVPLQALDDLSRSMVVDVDNAVRTSTNELALAIEEFGERRTAPFTQAVNNAKAALSQAFTVRQQLDDNTPETPAQRRELLTRVIVSAAHADRELASQTEAFEKLRDLVINAPARLDLLTQQYVELTTRIGPTQQRLAELHTEFDAAAMTSIAGNVTTATERLAFADRNISAARDLADQAVSGRQAGLVDAVRAAESALGQARALLDAVDSAATDIRHAVASLPAVVADIQTGIKRANQHLQQAQQPQTGRTGDLIAARDAAARALDRARGAADPLTAFDQLTKVDADLDRLLATLAEEQATADRLNRSLEQALFTAESRVRAVSEYIDTRRGSIGPEARTRLAEAKRQLEAAHDRKSSNPTEAIAYANAASTLAAHAQSLANADVQSAQRAYTRRGGNNAGAILGGIIIGDLLSGGTRGGLGGWIPTSFGGSSNAPGSSPDGGFLGGGGRF
What is the function of this protein?
May play a role in septum formation.
What are the official names of this protein?
UPF0603 protein MT2410.
What is the protein family that this protein belongs to?
Belongs to the UPF0603 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ERG6_CANGA
Sequence: MSESELRQRQAEFTKELHGEGAESRTGLTALLSKNRNAQREAVSKYLRHWDGKTDKEAEDRRLEDYNEATHSYYNVVTDFYEYGWGSSFHFSRFYKGENFQAAMARHEQYLAYMAGIKKGDLVLDVGCGVGGPARTIARFTGCNIIGLNNNDYQIQKAKYYAKKYNLQDHMDFVKGDFMNMEFEPNSFDKVYAIEATCHAPKLEGVYGEIYKVLKPGGTFAVYEWVMTENYDENNEEHRKIAYEIELGDGIPKMFTVDVAKQALKNVGFEVEVSKDLADEDDEIPWYYPLTGEWKYVQSLSDIATFFRTSYFGRKFTNCMVSIMEKVGVAPQGSVEVTAALENAAVGLVEGGRKKLFTPMFLFVAKKPEDAK
What is the function of this protein?
Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.
What are the official names of this protein?
Sterol 24-C-methyltransferase, Delta(24)-sterol C-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.