PharMolix/UniProtQA huggingface dataset:
Protein: BC11B_HUMAN
Sequence: MSRRKQGNPQHLSQRELITPEADHVEAAILEEDEGLEIEEPSGLGLMVGGPDPDLLTCGQCQMNFPLGDILVFIEHKRKQCGGSLGACYDKALDKDSPPPSSRSELRKVSEPVEIGIQVTPDEDDHLLSPTKGICPKQENIAGPCRPAQLPAVAPIAASSHPHSSVITSPLRALGALPPCLPLPCCSARPVSGDGTQGEGQTEAPFGCQCQLSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEPGPASSSLTPRLTIPPPLGPEAVAQSPLMNFLGDSNPFNLLRMTGPILRDHPGFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMRLNPMAIDSPAMDFSRRLRELAGNSSTPPPVSPGRGNPMHRLLNPFQPSPKSPFLSTPPLPPMPPGGTPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELAGEGLKAADGDFRHHESDPSLGHEPEEEDEEEEEEEEELLLENESRPESSFSMDSELSRNRENGGGGVPGVPGAGGGAAKALADEKALVLGKVMENVGLGALPQYGELLADKQKRGAFLKRAAGGGDAGDDDDAGGCGDAGAGGAVNGRGGGFAPGTEPFPGLFPRKPAPLPSPGLNSAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSSENGSLRFSTPPGDLLDGGLSGRSGTASGGSTPHLGGPGPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS
What is the function of this protein?
Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals.  Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed:27959755).  Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes (PubMed:16809611).  Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity).  May also function in the P53-signaling pathway (By similarity).
What are the official names of this protein?
B-cell lymphoma/leukemia 11B, BCL-11B, B-cell CLL/lymphoma 11B, COUP-TF-interacting protein 2, Radiation-induced tumor suppressor gene 1 protein, hRit1.
What are the subcellular locations of this protein?
Nucleus.
Protein: HSP18_CLOAB
Sequence: MFGMVPFRRNNNGLMRREDFFDKMFDNFFSDDFFPTTTFNGNAGFKVDIKEDDDKYTVAADLPGVKKDNIELQYENNYLTINAKRDDIVETKDDNNNFVRRERSYGELRRSFYVDNIDDSKIDASFLDGVLRITLPKKVKGKDNGRRIDIH
What is the function of this protein?
Probable chaperone.
What are the official names of this protein?
18 kDa heat shock protein, HSP 18.
What is the protein family that this protein belongs to?
Belongs to the small heat shock protein (HSP20) family.
Protein: DOM34_YEAST
Sequence: MKVISLKKDSFNKGGAVITLLPEDKEDLFTVYQIVDKDDELIFKKKFTSKLDEAGKKKSTDLVKLKIKVISEDFDMKDEYLKYKGVTVTDESGASNVDIPVGKYLSFTLDYVYPFTIIKQNFNKFMQKLLNEACNIEYKSDTAAVVLQEGIAHVCLVTSSSTILKQKIEYSMPKKKRTTDVLKFDEKTEKFYKAIYSAMKKDLNFDKLKTIILCSPGFYAKILMDKIFQYAEEEHNKKILDNKGMFFIAHCSTGYLQGINEVLKNPLYASKLQDTKYSKEIMVMDEFLLHLNKDDDKAWYGEKEVVKAAEYGAISYLLLTDKVLHSDNIAQREEYLKLMDSVESNGGKALVLSTLHSLGEELDQLTGIACILKYPLPDLDEDDGEE
What is the function of this protein?
Involved in protein translation.  Together with HBS1, may function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.  The complex formed by DOM34 and HBS1 has ribonuclease activity towards double-stranded RNA substrates, but does not cleave single-stranded RNA.  Acts as endonuclease; has no exonuclease activity.  Increases the affinity of HBS1 for GTP, but nor for GDP.  Promotes G1 progression and differentiation and is involved in mitotic and meiotic cell divisions.
What are the official names of this protein?
Protein DOM34.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LGT_ECOLI
Sequence: MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
What is the function of this protein?
Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
What are the official names of this protein?
Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase, Prolipoprotein diacylglyceryl transferase.
What is the protein family that this protein belongs to?
Belongs to the Lgt family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FILI_METH6
Sequence: MTLRRSILAFTGGMILVLALICSTFMCHMMMGTLSDLEEAYVHQKVDGTLFYLQEDLSSLKRAAEDWGHWNDTRDFVIGENDQYIQDNLNSWTLSGLDVDFMIYYDRSGNLFYSRAFNHATGEEVPAPGRLLSLAKDDPLIAHSSPEDGLTGIVSDPEGLLLVSSTTILDSHWKGPISGTFIVGRRLDGARAEGLARLSGIDLRMAATAPVGESEGTNSKTSLLIVKEDSDTLIATKTIDDVYGNPTVLLEAQVPREIRSRGLETIRRQVVGIFLASLLFGGLILLFLELSILMPLATITSSVEAIREQEKGQGSRIPTVGPAELATLAESINEMLDHLESYNQKLAMSEKRFRTIVDTAHDCIFIKDPKSRYVLVNPVMERIFQLPASKMLGERDEVFFSAETAARIREKDAGVLSGEPFVGEVSAHTRAGSSMTFHAVKVPLRDDRGQVTGICGIARDITDIKEAGVELLKRDRLLSASAAASYSLLVNYDIDQIIIDVLQLLGEAVEADRAYIFENQTVDGEVLMSQRYEWTKGEVEPQINNPVLQSLPYHPDSSTFYEIISRGRPYVGLVKDLPESERAYLAPQGIVSILIVPIFVEDRLWGFIGFDDCHRERFWSNGEISVLQVAAGSIGGAFIRSRTRADLVRAKGELQERIGEVEAKNAEMERFVYTVSHDLRSPLVTIQGFVGFLREDLSALDGDKIKIDLAMIEEAVLKMDHLLKDTLSLSRVGRVVNPPEEGSFGEIVHEALSQASGELRSRGIKVSLAEGWPRVRVDRLRVQEALTNLLDNSIKYMGDRPHPEIEVGWRPEGEETVFFVRDNGIGMDPDQWEKVFGLFYKIDPDSEGSGVGLAIVRRIIEVHGGRIWIESEEGRGTCVLFTLPTP
What is the function of this protein?
Could also catalyze the synthesis of the quorum sensing (QS) signal molecules carboxyl-acyl homoserine lactones (AHLs), which regulate the transition of the cellular morphology from short cells to filaments and of the carbon metabolic flux from biomass formation to methane production.
What are the official names of this protein?
Methanogenesis regulatory histidine kinase FilI, Acyl-homoserine-lactone synthase, AHL synthase.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PUR5_SYNR3
Sequence: MDYKSAGVDVEAGRHFVERIRTSVEATHRPEVLGGLGGFGGLCRLPAGLEKPLLVAGTDGVGTKLELAQECGRHHGVGIDLVAMCANDVITCGAEPLFFLDYIATGKLSPAAMAEVVEGIASGCSQSGCSLLGGETAEMPGFYPAGRYDLAGFCVAVVDEPRLIDGQTIQAGDQLLAIASSGVHSNGFSLVRRILEANQVPLETSQAALGGRSAAEALLEPTLLYAPLVKALLQSPELELRGMAHITGGGLPENLPRPLPQGLAAQIDPGSWQRPALFHWLQELGSVPERDLWHTFNLGIGYVLVLPESSCQQALEVVHNSGFTGWICGEIVVGQGVLGLPAGA
What are the official names of this protein?
Phosphoribosylformylglycinamidine cyclo-ligase, AIR synthase, AIRS, Phosphoribosyl-aminoimidazole synthetase.
What is the protein family that this protein belongs to?
Belongs to the AIR synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RT19_YEAST
Sequence: MQPAARLLSRSVWKGPNIVPLPIREAMTKGTPIRTNARAATILPQFVGLKFQIHNGKEYVPIEISEDMVGHKLGEFAPTRKRFSYTQTKNK
What is the function of this protein?
Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain.  The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.
What are the official names of this protein?
37S ribosomal protein S19, mitochondrial, Mitochondrial small ribosomal subunit protein uS19m.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
What are the subcellular locations of this protein?
Mitochondrion. Note=Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.
Protein: AMPA_GEOSM
Sequence: MRIEISSDNPLEHATPALVVGCFEDERGRVFEECDAALGGCLGRLAETREFTGKAGTTRLLHTLGKLPAERLLLVGLGKKADLTHERLRQAAGHAMQALRTSRAASFASTLPLASSLPRATESVAIGSLLGSYSFDLYKTKDKEQRFAFEEMTLMAPQPEREMARAVAEQAEQICRGVQLARDLVSHPGNVVTPGYLAQAARELAARHALEVRVYEQDELESLGMNALLGVGKGAAEPPRLIVLRYRGEGAKGRPVVLVGKGITFDSGGISIKPGPGMEEMKTDMAGAAAVFGTLEAAALLRLPVDLIGVVPTTENMPDGKAFKPGDVLASLSGTTIEITNTDAEGRLILCDALHFAQKFKPAAMIDLATLTGACVVALGHEASAVLGNDQRLVDALKKSGDETGERLWQLPLWDEYGEGMKSDIADIKNAGSRDGGTIKAAWFLKQFVGETRWAHLDIAGTAWSEKARPYSPKGATGVGVRLLIEYLRRK
What is the function of this protein?
Presumably involved in the processing and regular turnover of intracellular proteins.  Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.
What are the official names of this protein?
Probable cytosol aminopeptidase, Leucine aminopeptidase, LAP, Leucyl aminopeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase M17 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IF1_NOCFA
Sequence: MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLSRGRIVYRYK
What is the function of this protein?
One of the essential components for the initiation of protein synthesis.  Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds.  Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC).  Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.
What are the official names of this protein?
Translation initiation factor IF-1.
What is the protein family that this protein belongs to?
Belongs to the IF-1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CARA_PASMU
Sequence: MSEPAILVLADGSVFHGTSIGAKGHTVGEVVFNTAMTGYQEILTDPSYFRQIVTLTYPHIGNTGTNLEDCEANHVYASGLIIRDLPLLHSNFRSSMSLRDYLQTHNVVAIADIDTRRLTRILRDKGAQAGCIMTGEIDEAKALELAKSFGSMAGKDLAQEVSTGEIFTWTSGQWQLGKGFIEQTQAEFNVVAYDFGVKHNILRMLAERGCKITVVPAKTSAEQVLALNPDGIFLSNGPGDPEPCDYAISAIQTLLASKKPIFGICLGHQLLGLAAGGKTKKMAFGHHGANHPVQDLNTQKVFITSQNHGFEVDEASLPSHVRVTHRSLFDNSVQGIELSDQSAFSFQGHPEASPGPNDVAYLFDKFINEMRKANLSQLSTYVAHH
What are the official names of this protein?
Carbamoyl-phosphate synthase small chain, Carbamoyl-phosphate synthetase glutamine chain.
What is the protein family that this protein belongs to?
Belongs to the CarA family.
Protein: SSUD_ECOSM
Sequence: MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGYTGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGRALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLLGETVDFNGKHIHVRGAKLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAHGRKIRFGIRLHVIVRETNGEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAALHNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPHLEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVANDFIPRNVAQS
What is the function of this protein?
Catalyzes the desulfonation of aliphatic sulfonates.
What are the official names of this protein?
Alkanesulfonate monooxygenase, FMNH2-dependent aliphatic sulfonate monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the SsuD family.
Protein: ENCAP_RHOE4
Sequence: MTNLHRDLAPISAAAWAEIEEEASRTFKRHVAGRRVVDVEGPSGDDLAAIPLGHQVPINPLADGVIAHARQSQPVIELRVPFTVSRQAIDDVERGAKDSDWQPVKDAAKQIAFAEDRAIFEGYPAASITGVRASGSNPELKLPIDAKDYPEAISQAITSLRLAGVNGPYSLLLNADAFTAINETSDHGYPIREHLRRVLDGEIIWAPAIDGAFLLSTRGGDYELHLGQDLSIGYLSHDANSVELYFQESMTFLMYTSEAVVSLA
What is the function of this protein?
Shell component of a type 1 encapsulin nanocompartment.  Assembles into proteinaceous shells 21-24 nm in diameter.  Empty organelles can be expressed in E. coli.  Cargo proteins (DypB) are targeted to the interior via their C-terminal extensions.
What are the official names of this protein?
Type 1 encapsulin shell protein.
What is the protein family that this protein belongs to?
Belongs to the encapsulin family. Family 1 subfamily.
What are the subcellular locations of this protein?
Encapsulin nanocompartment.
Protein: DNLI_SULAC
Sequence: MEFKLIAEYFDRLEKISSRIQLTALLTDLLKKSDKDVIDKVIYITQGKLWPDFFEKPEIGLGEKLMIKALSVSTNIKEDEIEKQLRILGDLGEVAYKLKRTNSSQNVLSYLGSTKVTKLTVEEVYESLSKIALSEGEGSRDMKIRSLAGLLKKADPLEAKYIIRFIDGRLRVGIGDATIMDALANVFGGGTAARPLIERAYNLRADLGNIAKLLAENGIETIKSIKPEVGIPIRPMLAERLTDPSEILAKVGGKGIVDYKYDGERAQIHKKGEKVYIFSRRLENITRQYPDVVEYIKNSIKSNEVILEGEIVAIDKESGEILPFQNLMHRKRKNDIGEAIKEYPVNVYLFDLMYNDGEDYTQKPLPDRREKLEEIVTQNDIVKVADHKYIDKVNELVEYFHQAISDGTEGVIVKSIGKDSIYQAGARGFLWIKLKKDYQSEMADSVDLVIVGAFYGRGKRGGKLSSLLMAAYDPDKDTFYTVCKVASGFSDAELEEVQKMLSEAKLDKKDPRVESEIQPDIWVKPKYVAEIIGAEITLSPLHTCCKGVVSEEAGLSIRFPRFIRWRDDKSVEEATTPNEILEMYQSRLKKKVEDITET
What is the function of this protein?
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [ATP].
What is the protein family that this protein belongs to?
Belongs to the ATP-dependent DNA ligase family.
Protein: Y154_UREPA
Sequence: MVKDDKLVPSIRLLTPNELSEQWANPNSEINQITRAVLTIQGIDLKAIDLNQAAQIIYFCQANNLNPLNKEVYLIQMGNRLAPIVGIHTMTERAYRTERLVGIVQSYNDVNKSAKTILTIRSPGLKGLGTVEAEVFLSEYSTNKNLWLTKPITMLKKVSLAHALRLSGLLAFKGDTPYIYEEMQQGEAVPNKKMFTPPVAEVIEPAVENIKKVDFNEF
What are the official names of this protein?
Uncharacterized protein UU154.
Protein: ARLY_YERE8
Sequence: MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLTTAEQQQLEQALSVLLEEVQADPQAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELKTAVQQLQQALVITAEANQDAVMPGYTHLQRAQPVTFAHWCLAYAEMLARDESRLQDTLKRLDVSPLGSGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALSLSDLQKFSAVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
What are the official names of this protein?
Argininosuccinate lyase, ASAL, Arginosuccinase.
What is the protein family that this protein belongs to?
Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLSX_THEM4
Sequence: MKKIAIDLMGGDFAPAEILAGALSFAKDFKDVELYLVGIEDNFKNVSLPENCKKVTVEDYLPMDIKPTEALRRKKSTMYQSCKLVKENVVDAVVSAGNTGALLACATFVVGRMKNIERPTLAVPIPTKDGFCVLADAGANIDVKPSTLLQFGVMGVEYAKFLGIKNPKVGLLNVGTEENKGTQKEQEAFKLLKEHFKKNFMGNVEGNDINMGKVDVVVADGFHGNIAMKTMEGTAKLIVDVLKSNIKKNIISAIGALLMKSVFNRLKEKLDPRKYGGTFFVGVNGIVVKAHGNSDRIAIYHALKVAKDGIEASLTSNIEEAIRNVWNSRYGRD
What is the function of this protein?
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP).  This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
What are the official names of this protein?
Phosphate acyltransferase, Acyl-ACP phosphotransacylase, Acyl-[acyl-carrier-protein]--phosphate acyltransferase, Phosphate-acyl-ACP acyltransferase.
What is the protein family that this protein belongs to?
Belongs to the PlsX family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with the membrane possibly through PlsY.
Protein: PHYE_ARATH
Sequence: MGFESSSSAASNMKPQPQKSNTAQYSVDAALFADFAQSIYTGKSFNYSKSVISPPNHVPDEHITAYLSNIQRGGLVQPFGCLIAVEEPSFRILGLSDNSSDFLGLLSLPSTSHSGEFDKVKGLIGIDARTLFTPSSGASLSKAASFTEISLLNPVLVHSRTTQKPFYAILHRIDAGIVMDLEPAKSGDPALTLAGAVQSQKLAVRAISRLQSLPGGDIGALCDTVVEDVQRLTGYDRVMVYQFHEDDHGEVVSEIRRSDLEPYLGLHYPATDIPQAARFLFKQNRVRMICDCNATPVKVVQSEELKRPLCLVNSTLRAPHGCHTQYMANMGSVASLALAIVVKGKDSSKLWGLVVGHHCSPRYVPFPLRYACEFLMQAFGLQLQMELQLASQLAEKKAMRTQTLLCDMLLRDTVSAIVTQSPGIMDLVKCDGAALYYKGKCWLVGVTPNESQVKDLVNWLVENHGDDSTGLTTDSLVDAGYPGAISLGDAVCGVAAAGFSSKDYLLWFRSNTASAIKWGGAKHHPKDKDDAGRMHPRSSFTAFLEVAKSRSLPWEISEIDAIHSLRLIMRESFTSSRPVLSGNGVARDANELTSFVCEMVRVIETATAPIFGVDSSGCINGWNKKTAEMTGLLASEAMGKSLADEIVQEESRAALESLLCKALQGEEEKSVMLKLRKFGQNNHPDYSSDVCVLVNSCTSRDYTENIIGVCFVGQDITSEKAITDRFIRLQGDYKTIVQSLNPLIPPIFASDENACCSEWNAAMEKLTGWSKHEVIGKMLPGEVFGVFCKVKCQDSLTKFLISLYQGIAGDNVPESSLVEFFNKEGKYIEASLTANKSTNIEGKVIRCFFFLQIINKESGLSCPELKESAQSLNELTYVRQEIKNPLNGIRFAHKLLESSEISASQRQFLETSDACEKQITTIIESTDLKSIEEGKLQLETEEFRLENILDTIISQVMIILRERNSQLRVEVAEEIKTLPLNGDRVKLQLILADLLRNIVNHAPFPNSWVGISISPGQELSRDNGRYIHLQFRMIHPGKGLPSEMLSDMFETRDGWVTPDGLGLKLSRKLLEQMNGRVSYVREDERCFFQVDLQVKTMLGVESRGTEGSSSIK
What is the function of this protein?
Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region.  Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses.  Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc.  It also controls the expression of its own gene(s) in a negative feedback fashion.
What are the official names of this protein?
Phytochrome E.
What is the protein family that this protein belongs to?
Belongs to the phytochrome family.
Protein: GSK3_DICDI
Sequence: MSSKDQILEKDKKETDDNGNKKTTTTTSSSSSSSSSSKPRSNKFDKVIIKSNGVCYITEGVIGNGSFGVVTQAIVADTKEVVAIKKVLQDQRYKNRELQIMKMLNHINIVSLKNSFYTSDNDEVYLNLVLEYVPDTVYRVSRHYSMSKQPVPNIFVKLYIYQLCRSINYIHSLGICHRDIKPQNLLLDTSTSTLKLCDFGSAKILIKGETNVSYICSRHYRAPELIFGSTNYTTTIDVWSLGCVLAELLLGQPLFPGENGIDQLVEIIKVLGTPTKEQIHAMNPYYTSFKFPEIKANPWPRVFKAKDVPAESIDLISKILLYDPSSRLKPVEICAHPFFDELRDPKTCLPDGKPLPPLFNFTIAEQTSIGPKLAKTLIPSHAMNQIELPSPLFPNLAISSSNQSSSSNSNANVSSNLNSHSASPSTTSSSSSTPNSIPVQSPSTTNTTSSTTNNTTTTTTTTTTSNH
What is the function of this protein?
During cellular differentiation, may mediate an extracellular cyclic AMP stimulated signal transduction pathway that regulates prespore and prestalk B-cell proportions through inhibition of stalk cell formation and induction of prespore cell differentiation.  The cAMP receptor carC appears to activate gskA via the tyrosine kinases zakA and zak2, to stimulate prespore differentiation, while carD appears to negatively regulate gskA, to promote prestalk formation.
What are the official names of this protein?
Glycogen synthase kinase-3, GSK-3.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
Protein: CECB_DROME
Sequence: MNFNKIFVFVALILAISLGNSEAGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATARG
What is the function of this protein?
Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria.
What are the official names of this protein?
Cecropin-B.
What is the protein family that this protein belongs to?
Belongs to the cecropin family.
What are the subcellular locations of this protein?
Secreted.
Protein: PNMA3_MOUSE
Sequence: MPLNLLQDWCRGEHLNTQRSMLILGIPEDCSEDEFEETLHEALKHLGRYRIIGRMFRREENAQAFLVELARDFDYALVPREIEGKGGPWEVVVKPPHSDDEFLNRLNHFLEEERRTVSDMNRVLGTHSNHSPTKTTISADFWVWAQTLGAVMQPLLEQMLYRELRVFSGNTISIPGLLAFDSWLEHTTEMLQMWQVPEVEKRRRLMECLRGPALQVVNVLRANNAAITVKECLEALRQVFGSVDNRKIAQLKFCKAYQEPGEKVSSFVVRLETLLQKALEKNAISRKNVNQTRLKRILGGAILSAKLREKLKMLKQRRRPPGFLALVKLFREEEEEWEATRGSERSCYEGLELGPSPSNIGSEERELFVPAFGSVLEERPYQGSRRRRHRRRGQHRKGGVPRDDSQGTRKQNYDTFCYSCGEDGHIRVHCFNPSNRTLVKQKRQAAMEKGNRSWAWEKSHPKPKTK
What are the official names of this protein?
Paraneoplastic antigen Ma3 homolog.
What is the protein family that this protein belongs to?
Belongs to the PNMA family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: AQPZ_VIBVY
Sequence: MNKYLAELFGTFWLVLGGCGSAVLAAAFPDVGIGLLGVSLAFGLTVLTMAFAIGHISGCHLNPAVTIGLWAGGRFEAKEIVPYILAQVIGGVIAGGVLYTIASGQMGFDATSSGFASNGYGEHSPGGYSLTSALVTEIVMAMMFLLVILGATDQRAPQGFAPIAIGLCLTLIHLISIPVTNTSVNPARSTGVALYVGDWATAQLWLFWVAPILGALLGAVAYKLISGSNKD
What is the function of this protein?
Channel that permits osmotically driven movement of water in both directions.  It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells.  It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
What are the official names of this protein?
Aquaporin Z.
What is the protein family that this protein belongs to?
Belongs to the MIP/aquaporin (TC 1.A.8) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MEF2C_RAT
Sequence: MGRKKIQITRIMDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNSTNKLFQYASTDMDKVLLKYTEYNEPHESRTNSDIVETLRKKGLNGCDSPDPDADDSVGHSPESEDKYRKINEDIDLMISRQRLCAVPPPNFEMPVTIPVSSHNSLVYSNPVSSLGNPNLLPLAHPSLQRNSMSPGVTHRPPSAGNTGGLMGGDLTSGAGTSAGNGYGNPRNSPGLLVSPGNLNKNIQAKSPPPMNLGMNNRKPDLRVLIPPGSKNTMPSVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSADLSSLSGFNTASALHLGSVTGWQQQHLHNMPPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPPRDRTTTPSRYPQHTRHEAGRSPVDSLSSCSSSYDGSDREDHRNEFHSPIGLTRPSPDERESPSVKRMRLSEGWAT
What is the function of this protein?
Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes (PubMed:15862299).  Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development.  Enhances transcriptional activation mediated by SOX18.  Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission.  Crucial for normal neuronal development, distribution, and electrical activity in the neocortex.  Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis.  Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells.  May also be involved in neurogenesis and in the development of cortical architecture (By similarity).
What are the official names of this protein?
Myocyte-specific enhancer factor 2C, Myocyte enhancer factor 2C.
What is the protein family that this protein belongs to?
Belongs to the MEF2 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, sarcoplasm.
Protein: DPOL_BPPH2
Sequence: MKHMPRKMYSCDFETTTKVEDCRVWAYGYMNIEDHSEYKIGNSLDEFMAWVLKVQADLYFHNLKFDGAFIINWLERNGFKWSADGLPNTYNTIISRMGQWYMIDICLGYKGKRKIHTVIYDSLKKLPFPVKKIAKDFKLTVLKGDIDYHKERPVGYKITPEEYAYIKNDIQIIAEALLIQFKQGLDRMTAGSDSLKGFKDIITTKKFKKVFPTLSLGLDKEVRYAYRGGFTWLNDRFKEKEIGEGMVFDVNSLYPAQMYSRLLPYGEPIVFEGKYVWDEDYPLHIQHIRCEFELKEGYIPTIQIKRSRFYKGNEYLKSSGGEIADLWLSNVDLELMKEHYDLYNVEYISGLKFKATTGLFKDFIDKWTYIKTTSEGAIKQLAKLMLNSLYGKFASNPDVTGKVPYLKENGALGFRLGEEETKDPVYTPMGVFITAWARYTTITAAQACYDRIIYCDTDSIHLTGTEIPDVIKDIVDPKKLGYWAHESTFKRAKYLRQKTYIQDIYMKEVDGKLVEGSPDDYTDIKFSVKCAGMTDKIKKEVTFENFKVGFSRKMKPKPVQVPGGVVLVDDTFTIK
What is the function of this protein?
Polymerase responsible for protein-primed viral DNA replication by strand displacement with high processivity and fidelity (PubMed:3863101) (PubMed:2498321).  To start replication, the DNA polymerase forms a heterodimer with a free primer terminal protein (TP), recognizes the replication origins at both 5' ends of the linear chromosome, and initiates replication using as primer the OH-group of Ser-232 of the TP (PubMed:22210885).  This polymerase possesses three enzymatic activities: DNA synthesis (polymerase), primer terminal protein (TP) deoxynucleotidylation, which is the formation of a covalent linkage (phosphoester) between the hydroxyl group of a specific serine residue in TP and 5'-dAMP, a reaction directed by the second T at the 3' end, and 3' to 5' exonuclease activity (PubMed:2790959).  Exonuclease activity has a proofreading purpose (PubMed:2790959).  DNA polymerase edits the polymerization errors using an intramolecular pathway as the primer terminus travels from one active site to the other without dissociation from the DNA (PubMed:10493855).  DNA polymerization catalyzed by the DNA polymerase is a highly accurate process, but the protein-primed initiation is a quite inaccurate reaction (PubMed:8428945).  Since the polymerase initiates the replication on the second thymine, the TP-dAMP initiation product translocates backwards to recover the template information of the first nucleotide (sliding back-mechanism) (PubMed:19011105).
What are the official names of this protein?
DNA polymerase, Gene product 2, gp2, Protein p2.
What is the protein family that this protein belongs to?
Belongs to the DNA polymerase type-B family.