PharMolix/UniProtQA huggingface dataset:
Protein: LAA1_YEAST
Sequence: MANRSLKKVIETSSNNGHDLLTWITTNLEKLICLKEVNDNEIQEVKEIHTQLDEFVRYISVLENTDDLELHSVFISLSQLYTISIWRLKDEYPGVVFDSAAFLTNVLCEEDVSIDDGDTDPNQKKKKKKSSTKKKKYIYSPAKDIACTILVQLFENFGSSISSLIPLLFNAIFKNLKKIMEKSKYYHATFMTTLLQLFNAILRNSNNDDKILDPATYAKFSKLSKTVFDSISTDEKDFSVTFVSVLIECWTAHFKQTNFIREHSHDIIETIYSRFTEGEIGVYGFANDETRIFTAKSLAEILFDYYFSKNILTLQEVWSIYVKIFLNCDTRDVESGCFESIIHLINLNLLADNTFLSNSKYLDIVLSLSGVFSSYEVNNRSMNTLSRYLRYFQHMHEVILPHLNDSAKTQMLYYILGCSDTYQSSSKSDSASNFKYSIDAKPETQWLTLLQLDFTYVLISDLGSTFTTEENTVKEIRDKLVDLATCEIFTIRVHTVEILKVFLNNCPEYLSETIENSLRALSTDFKSTGKFIFHKNHGHAFIIANLIKGAESDYISYELIMRITVFSTSFIKNNTTSTSSNLYFKGLLCWILLIGLMNYKDEQYLKLQIPQLFLFWKVLLTHTYTYHDEDELYKNLEIRNHALTCLLTYLSNTTIDKEMAKQVSYLLTKCSNFNHSIDLKSKNIDNALLHNENRILQVYLKLEKYINSDFNSSLLILIVKNFSDPNLYTESSSSVLGSLKDIGNRKVSNKDDMESNIVLESSINTLLRQNNGFAFGLSSKITGDRIVNLSMSSAYKYDESISGSWPSKDYNWYNIFEVEVSKPISPILSLDSLILLYGSGSYSQIDRYAPQVTTSLIDSSMELFSSVFPFLNSKIQYSIMETLNLSMFSKMTTPLRSVAVAANVCSALHNALRIMQENNLELDYSVGQLIIESIKKIQFFNDIFLTKIKADCVGLLTAAIARTLGDEERQKFLTEQSRIFIKNVADMDEPYLRMFHVLSLATIFKYNSQYANFEEYFDVIFALMRDPHPVVHSWSLKAMHILLEKHLVIDLKTAALLLSSMEELLVQDKYGIYGRSTLRCNYNRDFNSHVAIGEISRTLTETVGPNFLELNTKVLDSFRNITLSMLISNNILNSITSIKMFENIATFKMKNILNYEIFILASKSIIKSSIVTGIGSSYFDTTFTGSNELISRTSSLKGAFENFDLLTLLYKLQMEEFFMKEMENLSWRYLALFPNSGSVKNYFTEWILHTFKRDNHWFDKLYSIFNMSLGRLFQSYNRDVSALLEVNGLKKSSEKEIKGEEEESIANVNQLTDTDAGGLDSENLQWKSRQIILNLILMLCLESEKYENLLLALSNKIADLIKISFRGSTVRNEGMKLTGLHILNFVLKNYSTMRDPQVPGSSILEQQEAQITSALMPAFSKGSSPTVMSFAITVAAEVLASNIMPPDKLGRISQLLIDLLGNFKDPNSGIRIGEAIIVTPKAKRKIELAVLDAWAEVVQRSITSSNDALFSFTRKYWSILVPLWIISLREYMMIKYNDNDSTVQVKNDSKENSLIEPRSTKIELYEPVWLNFVEALGCTLDSDVQVILASLNDEELEYFLFILFSQCLEAIVKNIDDHSVKMQVLPALHNVLKSNLCIKSIFEDDIITEVVEIMDRLISTGDSKEEFLLVDIISDLIIGYSKCNATPETFLQDIDKLYELLRLLMTIISERLPFIKYNVLTSEEDDNEIKISPTDISLLKKTFIAFESNISNFDNMFKVDLYSCLLFIIGKIYECSHREVIIPIILPLFKALVKALTESEDEKNIVLLEIFYGSIKDVIYHKLDSKNKVATILILLSNGYSKLSFQELNQCANILSEALNNPATQPIALQGFKRIISNIFKYPLLQYFMKLVIKRFFQDIQTNDSLSQASIKTKLIIQFSEEVIKQDHQKASLSIALCLSFFAAYHSAYTEKIDNEVASGIVALAKLDKNSFKEAISSTISPQQKAIIGSVMEAYVKSQSLGSVEEAFQLKSFD
What is the function of this protein?
Involved in the trans-Golgi network (TGN)-endosome transport.  Important for the correct localization of the adapter protein complex AP-1.
What are the official names of this protein?
AP-1 accessory protein LAA1, Large AP-1 accessory protein 1.
What are the subcellular locations of this protein?
Golgi apparatus. Note=Colocalizes with AP-1 adapter complex, with clathrin-coated vesicles to the late-Golgi apparatus and with ribosomes. Localization depends on ADP-ribosylation factor (ARF).
Protein: ARCA_VIBC3
Sequence: MNRLYVGSEVGQLRRVLLNRPERALTHLTPSNCHELLFDDVLAVEAAGVEHDAFANTLRTQDVEVLLLHDLLEETLAIPEARQWLLNTQISDFRFGPTFARELRHALNHLDDHHLTTLLLGGLAFSELHLESDSMLPKMRQPLDFVIEPLPNHLFTRDTSCWVYGGVSLNPMMKPARQRETNHLRAIYRWHPIFAQHPFIHYFGIDDLHYDNANIEGGDVLVIGKGAVLIGMSERTSPQGVENLAAALFKHGQASKVIAINLPKHRSCMHLDTVMTHMDVDTFSVYPEVMRKDLPTWRLTPKGNNGDMRVEQVPSYLHAIEQALGVDYLKIITTGGNSYEAEREQWNDANNVLTVKPGVVIGYERNVYTNEKYDKAGIKVLTIPGNELGRGRGGARCMSCPIERDGI
What are the official names of this protein?
Arginine deiminase, ADI, Arginine dihydrolase, AD.
What is the protein family that this protein belongs to?
Belongs to the arginine deiminase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DBP10_NEOFI
Sequence: MPHRAASPAMSENEFDITGALFQNDSDSDNEQPSAKSKRQPPKKVPSQALDFLGDVNEDDDDDEAFIAEQQTSANRKASNLKGRTVKKGGGFQAMGLSANLLKAIARKGFSVPTPIQRKTIPVIMDDQDVVGMARTGSGKTAAFVIPMIEKLKSHSTKVGARGLILSPSRELALQTLKVVKELGRGTDLKSVLLVGGDSLEEQFAMMAGNPDIVIATPGRFLHLKVEMNLDLSSIRYVVFDEADRLFEMGFAAQLTEILHGLPANRQTLLFSATLPKSLVEFARAGLQEPTLVRLDTESKISPDLQNAFFSVKSSEKEGALLYILQEVIKMPTGPTEVSQQRKEEDASAKNWKNKKRKRAEMEKAVNMRESPTKHSTIVFAATKHHVDYLYSLLSEAGFAVSYVYGSLDQTARKIQVQNFRTGMTNILVVTDVAARGIDIPILANVINYDFPSQPKIFIHRVGRTARAGRKGWSYSLVRDADAPYLLDLQLFLGRRLVVGREFGDQVNFAEDVVTGSLPRDGLSQSCEWVTKVLDDNADLAAQRTVAAKGEKLYMRTRNSASLESAKRSKQVVSSDNWTSIHPLFQDETSNLEAEREKMLARIGGYRPPETIFEVNNRRMGKHENVDALDTIKRVRTTLESKKKRAQANEKSEFLEDASDDEKAANEAGENENEGAFSDEDDDVPTGVADNMSMASDSELEVTFSSYSQSKENKAKKASAASFQNPEYFMSYTPNNNSLVEDRAYGVHSGTNSNFAQASRSATMDLAGDDGGRGFGEARTLMRWDKRHKKYVARQNDEDGSKGTRLVRGESGAKIAASFRSGRFDAWKRGNRLGRLPRVGEAEAPNLTAGLNAAISGKRFRHRKEQAPKRADPLRGDYEKMKKKAELAKERAMSKAGGAAPRGKSELKNTDDIRIARKLKQKRREKNARPSRKK
What is the function of this protein?
ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits and is required for the normal formation of 25S and 5. 8S rRNAs.
What are the official names of this protein?
ATP-dependent RNA helicase dbp10.
What is the protein family that this protein belongs to?
Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: ZBED3_HUMAN
Sequence: MRSGEPACTMDQARGLDDAAARGGQCPGLGPAPTPTPPGRLGAPYSEAWGYFHLAPGRPGHPSGHWATCRLCGEQVGRGPGFHAGTSALWRHLRSAHRRELESSGAGSSPPAAPCPPPPGPAAAPEGDWARLLEQMGALAVRGSRRERELERRELAVEQGERALERRRRALQEEERAAAQARRELQAEREALQARLRDVSRREGALGWAPAAPPPLKDDPEGDRDGCVITKVLL
What is the function of this protein?
Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin (By similarity).  Involved in transcription activation of Wnt target gene expression (By similarity).  Plays a role in symmetric division of blastomeres in the early stages of embryogenesis via regulation of mitotic spindle central positioning and organization of the F-actin filament network (By similarity).  Plays a role in regulating the distribution of cellular organelles, via modulation of cytoskeletal dynamics and cytoplasmic lattice formation (By similarity).
What are the official names of this protein?
Zinc finger BED domain-containing protein 3, Axin-interacting protein.
What are the subcellular locations of this protein?
Cytoplasm. Membrane. Secreted.
Protein: HFQ_SHEDO
Sequence: MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQVESFDQFVILLKNTVSQMVYKHAISTVVPARALHITPTQSSQPGYVQHDDAPAE
What is the function of this protein?
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations.  Also binds with high specificity to tRNAs.
What are the official names of this protein?
RNA-binding protein Hfq.
What is the protein family that this protein belongs to?
Belongs to the Hfq family.
Protein: RBSA1_BURL3
Sequence: MSRSESPRPLLEMRGISKTFPAVRALDNVSLTVYPGEIHSLMGENGAGKSTLMKILSGAYRADAGGEILIDGTRIDIDGPLAARDAGVAVIYQELCLSPNLSVAENIYIGRELRRGNRRWGTIDRAAMARGCEDVLARLSASFGPDTLVDTLSIAEQQLVEIARAVHTRARILVMDEPTTPLSSRETEHLFRLIRQLREEGLAIIYISHRMAEIYELSDRVSVLRDGTYVGTLERASLSAERLVAMMVGRDISGFYKKEHAPYDPGHLLLSVRDIADDARVRGCSLDLHAGEVLGIAGLVGAGRTELARLIFGAEPRVRGDVKVGERTFGAHSPRDAIDAGLVYLTEDRKRQGLFLDMSVRDNINISVCNRDARLGSLDLARGAERARDAIASLSIRVPDANVNVGALSGGNQQKVLLSRLLETKPRVLILDEPTRGVDIGAKSEIYRIINELARAGVGVIVISSELPEIIGVADRVLVMREGEIAGELGGYTQTPITQEAIIALATGSQAELADAH
What is the function of this protein?
Part of the ABC transporter complex RbsABC involved in ribose import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Ribose import ATP-binding protein RbsA 1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: RNPA_PSEPU
Sequence: MSQDFSREKRLLTPRHFKAVFDSPTGKVPGKNLLILARENGLDHPRLGLVIGKKSVKLAVQRNRLKRLMRDSFRLNQQLLAGLDIVIVARKGLGEIENPELHQHFGKLWKRLARSRPTPAVTANSAGVDSQDA
What is the function of this protein?
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus.  It can also cleave other RNA substrates such as 4. 5S RNA.  The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
What are the official names of this protein?
Ribonuclease P protein component, RNase P protein, RNaseP protein, Protein C5.
What is the protein family that this protein belongs to?
Belongs to the RnpA family.
Protein: PFKA_YARLI
Sequence: MIEGISFASFVTHEKPKFVRALDFYKALGFLPTKEYKHGTDHHATDEEGAGSIQEVWLTSSRAGVPSVTVKLRLSRHGNEHVSLPNLKHDWRSLVPSLVYYAPDLDAVRAAITPFLHEDHSTLLERPSHTNFIELYAIDPMGNLVGFSRRENPYSSAMQKPFSADDIGPQNFSKPNETKIKGKKRIGVMTSGGDAPGMCAAVRAVVRAGIARGCEVYAVREGYEGLVKGGDLIEPLSWEDVRGWLSLGGTLIGTARCKEFREREGRLAGALNMVKNGIDALIVIGGDGSLTGADLFREEWPSLIEELVTNGSITAEQAERHRHLDICGMVGSIDNDMATTDVTIGAYSSLDRICELVDFIDATAQSHSRAFVVEVMGRHCGWLALMAGTATGADYIFIPEAAPDATQWAEKMTRVVKRHRSQGKRKTVVIVAEGAIDSDLNPITAKMVKDVLDGIGLDTRISTLGHVQRGGPPVAADRVLASLQGVEAIDAILSLTPETPSPMIALNENKITRKPLVESVALTKKVADAIGNKDFAEAMRLRNPEFVEQLQGFLLTNSADKDRPQEPAKDPLRVAIVCTGAPAGGMNAAIRSAVLYGLARGHQMFAIHNGWSGLVKNGDDAVRELTWLEVEPLCQKGGCEIGTNRSLPECDLGMIAYHFQRQRFDGLIVIGGFEAFRALNQLDDARHAYPALRIPMVGIPATISNNVPGTDYSLGADTCLNSLVQYCDVLKTSASATRLRLFVVEVQGGNSGYIATVAGLITGAYVVYTPESGINLRLLQHDISYLKDTFAHQADVNRTGKLLLRNERSSNVFTTDVITGIINEEAKGSFDARTAIPGHVQQGGHPSPTDRVRAQRFAIKAVQFIEEHHGSKNNADHCVILGVRGSKFKYTSVSHLYAHKTEHGARRPKHSYWHAIGDIANMLVGRKAPPLPETLNDEIEKNIAKEQGIIDPC
What is the function of this protein?
Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
What are the official names of this protein?
ATP-dependent 6-phosphofructokinase, ATP-PFK, Phosphofructokinase, Phosphohexokinase.
What is the protein family that this protein belongs to?
Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MAN7_ARATH
Sequence: MKLLALFPFLAIVIQLSCWELGTDALPSGGFVRTKGVQFSLNGYPYYANGFNAYWLMYVASDPSQRSKISTAFQDASRHGLTVARTWAFSDGGYRALQYSPGSYNEDMFQGLDFALAEARRHGIKIILSFANNYESFGGRKQYVDWARSRGRPVSSEDDFFTDSLVKDFYKNHIKAVLNRFNTFTKVHYKDDPTIMAWELMNEPRCPSDPSGRAIQAWITEMAAHVKSLDRNHLLEAGLEGFYGQSSPQSKTLNPPGQFGTDFIANNRIPGIDFVTVHSYPDEWFPDSSEQSQMDFLNKWLDAHIQDAQNVLHKPIILAEFGKSMKKPGYTPAQRDIVFNTVYSKIYGSAKRGGAAAGGLFWQLLVNGIDNFQDGYGIILSQSSSTVNVISQQSRKLTLIRKIFARMINVEKWKRARGQGQVGKRGHKINN
What is the function of this protein?
Required for both, loosening of the micropylar endosperm, and rupture of the seed coat in germinating seeds.  May participate in the hydrolysis of the mannans in the cell wall of germinating seeds.
What are the official names of this protein?
Mannan endo-1,4-beta-mannosidase 7, Beta-mannanase 7, Endo-beta-1,4-mannanase 7, AtMAN7.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 5 (cellulase A) family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRHO_XANOP
Sequence: MITNTAAYQFVTIQHPQTLAASVLAQAEQQALKGSVLIAEEGINLFLAGDAEQIGAFYAWLQADARFARMRIKYSESAYQPFARLKVKIKPEIISFRRDDASPLQGRAPSVTPAVLREWLRNGQDDRGRPLVLLDTRNAQEVVYGTFQGALTLPIDTFTELPGALESHRAALADATVVSFCTGGIRCEKAALWMQADGMDNVLQLEGGILGYFEEVGGEGYDGRCFVFDERVALDPELKPLVDAERPAKTGKI
What is the function of this protein?
Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.
What are the official names of this protein?
tRNA uridine(34) hydroxylase, tRNA hydroxylation protein O.
What is the protein family that this protein belongs to?
Belongs to the TrhO family.
Protein: RL27_BRADU
Sequence: MAHKKAGGSSRNGRDSKGKRLGIKAFGGEVVIPGNIIARQRGTTWHPGLNVGMGTDHTLFAKIEGRVTFQAKANGRTFVSVLPIAEAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: NNRE_DAPPU
Sequence: MHPHSYLNQSDAIALDVELFNYFGVEQLMELAGLSCASAIAEGFPESKNVLIVVGPGNNGGDGLVCARHLKMFGYSPEIFYPKRTAKTLYENLTKQCELFEIPFLTACPTTEGLNSKYSLVVDALFGFSFKAPVRKEFTEIIDNMLHMSTPCCSIDIPSGWDVENGPLDQDNSLKPAMLISLSAPKLCARFFHGIHYLGGRFIAPALATKYKLKLPNYPSTHNCVRL
What is the function of this protein?
Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.  This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
What are the official names of this protein?
NAD(P)H-hydrate epimerase, NAD(P)HX epimerase.
What is the protein family that this protein belongs to?
Belongs to the NnrE/AIBP family.
Protein: DNAA_BORBZ
Sequence: MEKSKNIWSLILTEIKKELSEEEFYVWFENLCFLESIGDNIKISTPNLFHKNQIEKRFTKKIKEILIKNGYNNIVIVFTNQPPKTHSNKQETKNPALNETFSKFDKLKEKTTSKEAIQNIQDRIKMYIKKEEEEEPTNFKNPFLKKRYTFENFIIGPNNKLAYNASLSISKNPGKKYNPCLIYGGVGLGKTHLLQSIGNKTEELHHNLKILYVTAENFLNEFVESIKTHETKKFKKKYRYLDMLLIDDIHDLQKKEGIQEELFHTFNALYEDNKQLVFTCDRSPSELTNFTDRLKSRFTRGLNVDISKPNFELRAAIVEKKAEEDGINVPKNILNLVAQKVTTNVRDLEAAVTKLKAYIDLDNIEIDIEIVEKIIKEIIIYEKETTNEPNNKINIENIKKILLRELKITHKDIEGHSKKPEITKARHIYAYLLRNFTELSTVEIGKIIGGKTHSTVLYSINKIDRDRNNDKEINNLITELMNKIKKN
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPG_ECO81
Sequence: MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
What are the official names of this protein?
ATP synthase gamma chain, ATP synthase F1 sector gamma subunit, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: HSLO_STREM
Sequence: MDKLIKTISVSGAFRAYVLDCTETVRAAQERHHTLSSSTVALGRTLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATGEVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNVLLDQEDKVKVAGGFMLQVLPEASDEEISRYEKRIQEMPAISSLLASENHIDALLAAIYGKEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQFDQADLEVLINDKT
What is the function of this protein?
Redox regulated molecular chaperone.  Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation.  Plays an important role in the bacterial defense system toward oxidative stress.
What are the official names of this protein?
33 kDa chaperonin, Heat shock protein 33 homolog, HSP33.
What is the protein family that this protein belongs to?
Belongs to the HSP33 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CABL1_HUMAN
Sequence: MAAAAAAATTAACSSGSAGTDAAGASGLQQPPPQPQPQPAAAAPAQPPPEPPRKPRMDPRRRQAALSFLTNISLDGRLPPQDAEWGGGEEGGAAKPGAGGACGARTRFSLLAAAERGGCIALAAPGTPAAGLAAGSGPCLPQPSSLPPLIPGGHATVSGPGVARGFASPLGAGRASGEQWQPPRPAPLAACAQLQLLDGSGAAGQEELEEDDAFISVQVPAAAFLGSGTPGSGSGSRGRLNSFTQGILPIAFSRPTSQNYCSLEQPGQGGSTSAFEQLQRSRRRLISQRSSLETLEDIEENAPLRRCRTLSGSPRPKNFKKIHFIKNMRQHDTRNGRIVLISGRRSFCSIFSVLPYRDSTQVGDLKLDGGRQSTGAVSLKEIIGLEGVELGADGKTVSYTQFLLPTNAFGARRNTIDSTSSFSQFRNLSHRSLSIGRASGTQGSLDTGSDLGDFMDYDPNLLDDPQWPCGKHKRVLIFPSYMTTVIDYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGACVLLAAKIGSDLKKHEVKHLIDKLEEKFRLNRRELIAFEFPVLVALEFALHLPEHEVMPHYRRLVQSS
What is the function of this protein?
Cyclin-dependent kinase binding protein.  Enhances cyclin-dependent kinase tyrosine phosphorylation by nonreceptor tyrosine kinases, such as that of CDK5 by activated ABL1, which leads to increased CDK5 activity and is critical for neuronal development, and that of CDK2 by WEE1, which leads to decreased CDK2 activity and growth inhibition.  Positively affects neuronal outgrowth.  Plays a role as a regulator for p53/p73-induced cell death (By similarity).
What are the official names of this protein?
CDK5 and ABL1 enzyme substrate 1, Interactor with CDK3 1, Ik3-1.
What is the protein family that this protein belongs to?
Belongs to the cyclin family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Located in the cell body and proximal region of the developing axonal shaft of immature neurons. Located in axonal growth cone, but not in the distal part of the axon shaft or in dendritic growth cone of mature neurons (By similarity).
Protein: RS6_STRT1
Sequence: MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKDWEKRRLAYEIQDFREGLYHVVNVEANDATALNEFDRLSKINGDILRHMIVKLDA
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MYG_OCHPR
Sequence: MGLSDGEWQLVLNVWGKVEADLAGHGQEVLIRLFKNHPETLEKFDKFKNLKSEDEMKGSDDLKKHGNTVLSALGGILKKKGQHEAELKPLAQSHATKHKIPVKYLEFISEAIIQVLQSKHPGDFGADAQGAMSKALELFRNDMAAKYKELGFQG
What is the function of this protein?
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
What are the official names of this protein?
Myoglobin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: AMZ1_HUMAN
Sequence: MLQCRPAQEFSFGPRALKDALVSTDAALQQLYVSAFSPAERLFLAEAYNPQRTLFCTLLIRTGFDWLLSRPEAPEDFQTFHASLQHRKPRLARKHIYLQPIDLSEEPVGSSLLHQLCSCTEAFFLGLRVKCLPSVAAASIRCSSRPSRDSDRLQLHTDGILSFLKNNKPGDALCVLGLTLSDLYPHEAWSFTFSKFLPGHEVGVCSFARFSGEFPKSGPSAPDLALVEAAADGPEAPLQDRGWALCFSALGMVQCCKVTCHELCHLLGLGNCRWLRCLMQGALSLDEALRRPLDLCPICLRKLQHVLGFRLIERYQRLYTWTQAVVGTWPSQEAGEPSVWEDTPPASADSGMCCESDSEPGTSVSEPLTPDAGSHTFASGPEEGLSYLAASEAPLPPGGPAEAIKEHERWLAMCIQALQREVAEEDLVQVDRAVDALDRWEMFTGQLPATRQDPPSSRDSVGLRKVLGDKFSSLRRKLSARKLARAESAPRPWDGEES
What is the function of this protein?
Probable zinc metalloprotease.
What are the official names of this protein?
Archaemetzincin-1, Archeobacterial metalloproteinase-like protein 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase M54 family.
Protein: GLMM_SHESA
Sequence: MSERKFFGTDGIRGKVGSGQMTPELALKLGWAAGRVLSRSGTKKVIIGKDTRISGYMFESALEAGLSAAGLNVMLMGPMPTPAVAYLTRTFRAEAGVVISASHNPYYDNGIKFFSTDGSKLDDNLELEIEAELEKPLECVESHLLGKVSRIEDARGRYIEYCKGNFPADQTLTGLKIVVDCAHGATYHIAPAVFRELGAEVIAIGDKPNGVNINDKVGATSMAKICETVLTEGADLGIALDGDGDRIMMVNSRGEVIDGDQILYILACDAKARGVLRGGVVGTLMSNLGLDLALQALDIPFARSKVGDRYVMELLKELDWRIGGENSGHILNLDHGTTGDGIVAGILVLAAMRRQNATLEQLTAPMEMLPQVLVNVRFEGEHDPLSSDKVKAAQAQVESELGARGRVLLRKSGTEPLIRVMVEGDDHNTVLAHANLIADAVKSAS
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: Y2020_ARCFU
Sequence: MVKIRLHTTVSSETARKIEDLKKKHRTTSSVVEKAVDLLYTSENFSRLGDEDLLILAFIRELNFMLCAKDHYTALVEGDAERAVRESMIEMAVKYLSKKPISDLDFEELLSVVARLWNLLNRAEHAEVQKDGEKLNFVFYHDMRSKAVSELHLNLLKYLYEKYYSKKYEMQVDTITVNGFSVLFFPKDSVD
What are the official names of this protein?
Uncharacterized protein AF_2020.
Protein: RSMJ_DICNV
Sequence: MTDYFALKERPPYFPERVPCHILEHVPQGFYLAKHEQRWALCCTDKKPIHIDFTDTLYRRGGKEYLPKAFKNMNGKRIFDATAGWGRDSWLLACRGFQVTLCERQAYLYTLLAQAIELAKNTPETAATAAQLTLVYQDSCQYLRTTSTQFDAIYLDPMYPPRQKSAKVKKEMAILHILLDDEAGDTAENLLLLQTARARCARVVVKRPHTAPPLGNQVPRYCIDAPNTRFDVYLH
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: LSPA_BURCJ
Sequence: MAKTLSKPASGALAPWLGISLIVILFDQLSKIAILKTFAYGAQHALTSFFNLVLVYNRGAAFGFLSTASGWQRWAFTALGVGATLVICFLLKRHGHQRLFSVSLALILGGALGNVIDRLVYGHVIDFLDFHLGAWHFPAFNLADSAITIGAVLLIYDELRRVRGSR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: COPZ_STAA2
Sequence: MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
What is the function of this protein?
Chaperone that serves for the intracellular sequestration and transport of Cu(+).  Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) (By similarity).
What are the official names of this protein?
Copper chaperone CopZ.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACDE1_METAC
Sequence: MVDTAKNTKLFTSYGVSTSKTVTPEIAAKLISKAKRPLLMVGTLTLDPELLDRVVKISKTANIPIAATGSSLASLADKDVDAEYINAHMLGFYLTDPNWPGLDGNGNYDTVIVLGFKKFYINQVLSAAKNFSNLKTIAIERGYIQNATMSFGNLSKADHYAALDELIDLL
What is the function of this protein?
Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy.  The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.  The precise role of the epsilon subunit is unclear; it may have a stabilizing role within the alpha(2)epsilon(2) component and/or be involved in electron transfer to FAD during a potential FAD-mediated CO oxidation.
What are the official names of this protein?
Acetyl-CoA decarbonylase/synthase complex subunit epsilon 1, ACDS complex subunit epsilon 1, ACDS complex carbon monoxide dehydrogenase subunit epsilon 1, ACDS CODH subunit epsilon 1.
What is the protein family that this protein belongs to?
Belongs to the CdhB family.
Protein: TDRD3_XENTR
Sequence: MLLIALNTDLRTTGKKFLPNDINGGKVEKVNGPCVLQIQKIRNISAPKDNEESQAAPRMLRLQLTDGHTSCTAIELNYLSKISLNTPPGTKIKLLGTIEVKNGYLLLDDTNTVVLGGEVEHLIEKWELQRSLSKHSRSNIGIEGGPPPFVPFGQRCASVASVDSKELDSRKTLQASSVTKPVGENDEFEKQRTAAIAEVAKSKETKTFGGGGNAGSNLNPGAGGSRNKEVFQKEKIIRAEGKSEGVYRELVDEKALRHITEMGFSKDAARQALMDHSNNVEAALNSLLTGNKSKPVQGPPARGKGKGRGRTRAEEDDELTSARPSAPSTLFDFLESKMGSFSIEDHKLQSQSQSQVHQKPLNLEQNGIKDYNHKDYNQPRQFTRNDTRAPRNEKPPRFQKEIQASRQYEGNGPPKSRGSEKQSSSVAEQWMEERNKCERGYPRNDRLKDFSHLPSSHQNEGSYKKSYTNPMQGRGMKGGNHTEVKEEFHHQNSNTEGSHQKRGKKDDQRYNSEFYTDRRARTGNTETFTNIPNEKCFSANNELSNFQTILIKDGANDLSNGEVDQKARRFGPIKPIGTNLNSSHEDKSKMFSYNNAKKRSGPIKQERPLEAVYSGFSWRPGDECLALYWEDNKYYRAEVEALHSSGTTAVVKFSDYGNYEEVLLENIRPIQAEAWEEEGDFGDFRRGGDGQPRRSTRPTQQFYQPPRARN
What is the function of this protein?
Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins.  In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci.  In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By similarity).
What are the official names of this protein?
Tudor domain-containing protein 3.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associated with actively translating polyribosomes and with mRNA stress granules (By similarity).