PharMolix/UniProtQA huggingface dataset:
Protein: TNR1B_MOUSE
Sequence: MAPAALWVALVFELQLWATGHTVPAQVVLTPYKPEPGYECQISQEYYDRKAQMCCAKCPPGQYVKHFCNKTSDTVCADCEASMYTQVWNQFRTCLSCSSSCTTDQVEIRACTKQQNRVCACEAGRYCALKTHSGSCRQCMRLSKCGPGFGVASSRAPNGNVLCKACAPGTFSDTTSSTDVCRPHRICSILAIPGNASTDAVCAPESPTLSAIPRTLYVSQPEPTRSQPLDQEPGPSQTPSILTSLGSTPIIEQSTKGGISLPIGLIVGVTSLGLLMLGLVNCIILVQRKKKPSCLQRDAKVPHVPDEKSQDAVGLEQQHLLTTAPSSSSSSLESSASAGDRRAPPGGHPQARVMAEAQGFQEARASSRISDSSHGSHGTHVNVTCIVNVCSSSDHSSQCSSQASATVGDPDAKPSASPKDEQVPFSQEECPSQSPCETTETLQSHEKPLPLGVPDMGMKPSQAGWFDQIAVKVA
What is the function of this protein?
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha.  The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity).
What are the official names of this protein?
Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: NRDR_RUEPO
Sequence: MRCPFCGNIDTQVKDSRPAEDHVSIRRRRFCPACGGRFTTYERVQLRDLVVIKTSGKREDFDRDKLERSIRISMQKRPIDPERIDQMISGIVRRLESMGETDIPSKKIGEIVMEALARIDTVAYVRFASVYKNFQAADDFEDFVHELRPPSPPTEE
What is the function of this protein?
Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.
What are the official names of this protein?
Transcriptional repressor NrdR.
What is the protein family that this protein belongs to?
Belongs to the NrdR family.
Protein: YR7H_ECOLX
Sequence: MGSACSAESAHSCQHVLPVAPGCGAMRMHDRLHQNVDVWKLGNQTWSTPLMYPKMELVEYNIAISKCINGKSSKVDHHLFSFLVFPKAMPRDATVSQHIVNCVD
What are the official names of this protein?
Protein ORFh in retron Ec67.
Protein: XERC_PELTS
Sequence: MYVHIDNFLVYLRVEKNASPRTTESYQKDLFHGLDYFASRLGKEDHAIVPSDIDHRIFRHYLAHMQKQGLARATMARRLAAWRSFYRYLYREKIIDGNPLLRVASPKLEKRLPRFLYEDEAKELVEAPDTKQPLGMRDRALLETLYAGGLRISELVLLDLGDLDISSGYIRVTGKRARERLVPLGSMAVEALQAYLAKARPRLMANSVAKKINNALFLNCRGERLSARGIRKILDKYVEKVSLERKISPHTLRHSFATHLLNAGADLRSVQELMGHVRLSSTQVYTHVTGERLKKVYRKSHPRAKG
What is the function of this protein?
Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules.  The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division.  It also contributes to the segregational stability of plasmids.
What are the official names of this protein?
Tyrosine recombinase XerC.
What is the protein family that this protein belongs to?
Belongs to the 'phage' integrase family. XerC subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EFTS_STAS1
Sequence: MAISAKLVKELREKTGAGMMDCKKALTETDGDIDKAVDFLREKGIAKAAKKSDRIAAEGLVHVEERGNEAAIVEINSETDFVARNEGFQQLVKEIAIQVLDTKAETVEALLETNLPDGKSVDQRVKEAISTIGEKLSIRRFAVRTKTDNDSFGAYLHMGGRIGVLTVVEGSTDAEAAKDVAMHIAAINPKYVSSEQVSEDEIAHERDVLKQQALNEGKPENIVEKMVEGRLRKYLQEICAVDQNFVKNPDQTVEAFLKSKGGKLVDFVRYEVGEGMEKREENFADEVKGQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RIBB_YERPE
Sequence: MNQTLLSDFGTPVERVERAIDALRNGRGVMVLDDESRENEGDMVFAAEAMTLEQMALTIRHGSGIVCLCITDERRQQLDLPMMVTHNSSQFQTAFTVTIEAAEGVTTGVSAADRLTTIRKAIADNAKPADLNRPGHVFPLRGQPGGVLSRRGHTEASIDLATLAGYKPAGVLCELTNDDGSMAHAPEVIAFAKLHDMPVVTIDDLAAYLQSRAKKAS
What is the function of this protein?
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
What are the official names of this protein?
3,4-dihydroxy-2-butanone 4-phosphate synthase, DHBP synthase.
What is the protein family that this protein belongs to?
Belongs to the DHBP synthase family.
Protein: RASF6_RAT
Sequence: MTTMDHRFPSRIFVNERTSITREQLNSLLETYNVFYENQKNLHILYGQTEDGQLIVEGMLDIFWGVKRPIQLKIQDEKQISSFDLLKSPETFSSKGRMTRWGEFDDLYRISEMDKTQALAPEARHTPEDYLSCYSVLKQCADEEPESPLLYRTVSEAALVRKRMRAPEMYRKDRMGTLAKHRASINGHVYDHETSIFTPTFGSETKVRANSIMKTEEVIKQLLQKFKIENSPRDFALYIIFGTGEKRKLKKTDVPLLQRLIQGPSKSNARIFLMDKDAEEISSDVAPYINFHFSFLKSILQRLDEEEKMEIERIMAKFNTERAFILKCLQSKRAAKTETTV
What is the function of this protein?
Involved in the induction of apoptosis.  May act as a Ras effector protein.  May suppress the serum-induced basal levels of NF-kappa-B.
What are the official names of this protein?
Ras association domain-containing protein 6.
Protein: HSSS_STAA9
Sequence: MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKIMKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTVDQKGHKTFYGEPFREDTLSQNAINNVLNNKDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDEIGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVDQLIKDIIRHEQFAADEKSLIILADLESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISNDGSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTITLPNNSH
What is the function of this protein?
Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence.  HssS functions as a heme sensor histidine kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to an aspartate residue of HssR.  HssR/HssS activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity).
What are the official names of this protein?
Heme sensor protein HssS.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: DTML5_DICDI
Sequence: MKIFIIKIILVLFNYVLLSYSINQDLNILNVYDVRFAQTHVIPIEGKSWILNNKTYTLTIVGNRDSLLLVKFIDISITGTSSIKTVTTKTTKEEIKATILTNTYNVMVWNNDIVMGTRLLNDPNQLPPTESNGEQYSNEHHSIMIPKEWVKPGMKLQFFENSNSFIKSSKFIFPNVGQDYTLKMWTLPFYLFGANDTNTRPFNQTKNIDDSISAGLSQVYSCSNILSLNHPIQRVDWPYLVLGPRNGLPGMLITNSDQKKDGYAIMEGVLNILTGIRVAFGESTSSIQIYAPLLHLGANGKYADTYGGLGGSSRGTGDYRYSDTFVHEQGHAMGLPHAGEAFASGSYPYVNGSLLGSEWGFDINHYEFLSITLSNTSKNYKGCEKKNVKDTQNRCVKQSVMQSGAGDRSSNYLFSMFSDFEMSIIQNYFKNSIYYDEQIGKYKKWNETIGSYYEYKPITKDYGFYRLDDGIPIERDIDVYTIVFTYSLVGPEPLSQIYPLLKSKGNLIRQFDPTNKTEMKLITPNTGSIPWYCFNSGCDYTIRVTYDDDSIKHILLQQGKRQYWKPMGDFKLNFNDPTSSDSFLLGVINVKAIKTIKKVELLETLMAWNGISKNSKLLTFKLF
What are the official names of this protein?
Dictomallein-5.
What is the protein family that this protein belongs to?
Belongs to the dictomallein family.
What are the subcellular locations of this protein?
Secreted.
Protein: TRPC_RHIEC
Sequence: MSDILKKIELYKREEIAAAKAAVSLADLKAMQAGQSAPRGFYQALTAKREAGHFGLIAEIKKASPSKGLIRPDFDPPALAKAYEAGGAACLSVLTDTPSFQGAPEFLTAARAACALPALRKDFMFETYQVHEARAWGADCILLIMASLTDDEAERLQDESFSLGMDVLVEVHDASEMERALKLSSPLIGINNRNLRTFEVGLTVSETLASMVPDDRLLVGESGIFTHADCKRLQAAGINTFLVGESLMRKDDVTAATRALLVGEAAIAAE
What are the official names of this protein?
Indole-3-glycerol phosphate synthase, IGPS.
What is the protein family that this protein belongs to?
Belongs to the TrpC family.
Protein: HIS7_RUBXD
Sequence: MARVGELERKTGETFVRVRLEVDGEGRADVSTGVGFLDHLLHLLAHHSGMDLEVRAEGDTWVDDHHTVEDTGLVLGRALDQALGDRSDLVRFADASVPLIEALSTAAVDLGGRSHLTCNTGPLPEKIGTFDTELFPEFLRAFTQYGRFTLHLNCHYGHNAHHKVESGVKALAVALRAAVSRRSSGTASTKGVVD
What are the official names of this protein?
Imidazoleglycerol-phosphate dehydratase, IGPD.
What is the protein family that this protein belongs to?
Belongs to the imidazoleglycerol-phosphate dehydratase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_SACHY
Sequence: MTIAVGRVTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFALIGFMLRQFELARSVQLRPYNAISFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: GUAC_STRPM
Sequence: MFNDIPVFDYEDIQLIPNKCIITSRSQADTSVTLGKYQFKLPVIPANMQTIIDETIAERLAKEGYFYIMHRFDEDSRKPFIKRMHEQGLIASISVGVKACEYEFVTSLKEDAPEFITIDIAHGHANSVIDMIKHIKTELPETFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKSIRFGASMVMIGSLFAGHIESPGKTVEVDGETFKEYYGSASEYQKGEHKNVEGKKILLPTKGHLSDTLTEMQQDLQSSISYAGGKDLDSLRHVDYVIVKNSIWNGDSI
What is the function of this protein?
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.  It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
What are the official names of this protein?
GMP reductase, Guanosine 5'-monophosphate oxidoreductase, Guanosine monophosphate reductase.
What is the protein family that this protein belongs to?
Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily.
Protein: NUF2_GIBZE
Sequence: MAYNPRMSIIPTSQQNSRTRKKEEEADAFMRLPDREIVGCITDIGITFTVADLQKPNAAHVQQIFEWFAELLLNATRETVEPAMRAAAEDIAGEYADIIPSDTRNLMGFYVSLRRLLFECGITDFSFNDLYKPTYDRLVKIFSYLINFVRFRESQTAVIDQHYNKAESTKTRIETLYGENQENEGRLEDMKRNRKAMEAQVQQKTMRNEELKKRLLELRRNQERVAARLEEAKQKKGELTTALEQKTHEKVTLKQESTKLRPYVLQSASDLQENLAELRDILNNDKSHIDALDRRARALQTSTDSFSVVSTDVASCIKILDEIASELAKEEEELARNAKQRDALSERSNNAREVERTETMLKRQLSKWMERTEKLREQSNHKAHEAKEKMHELRAIHRQLTEEHTEKGKEMEVRRVRIEQTEKKMLDLKENIENEVHSAHEEYRKMEAHIKLYIAEMEQAIA
What is the function of this protein?
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
What are the official names of this protein?
Probable kinetochore protein NUF2.
What is the protein family that this protein belongs to?
Belongs to the NUF2 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with kinetochores.
Protein: EFP_STAA3
Sequence: MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKVEPAMIENRRMQYLYADGDNHVFMDNESFEQTELSSDYLKEELNYLKEGMEVQIQTYEGETIGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTLNVPLFVNEGDVLIINTGDGSYISRG
What is the function of this protein?
Involved in peptide bond synthesis.  Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro.  Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
What are the official names of this protein?
Elongation factor P, EF-P.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TSR3_METBU
Sequence: MKKQIDKDYHLHIFHAKQCDPKKCTGKKMARFELARIFDKVQKIPRGSILLDPMAKQALSPADKHEQNITVLDCSWETVEEVFPHLMRLHLQHRALPYLVATNPVNFGRPFKLTSVEAFAAALYILGNKKQAEKILSKFNWGHVFLDMNKEPLEDYSKAKDSNEIIKIQSEYM
What is the function of this protein?
Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M. jannaschii 16S rRNA.  It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).
What are the official names of this protein?
16S rRNA aminocarboxypropyltransferase.
What is the protein family that this protein belongs to?
Belongs to the TDD superfamily. TSR3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_YERPE
Sequence: MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQIRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAATVLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVIHPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYAPSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: MURE_LEPBL
Sequence: MKMKLTNLLHEFPELKLGSLPSGKNPDSVPIEYIQSDSRKTNPEDIFCVPESIGTKKGEFISNTKASVILLHRSSNISIDSSKIVLECEEDPEQLQGRIASFLLGHPSKTLEIVAVTGTNGKTSLTNILFALAKDQGKICGLIGTIGVKFGDRSIDTGYTTPDASSLNLILKQMKDEGVTTVFMEASSHGLKLGRIGGISLKAGVFTNLTQDHLDFHSDMEDYFESKFRLFEILDVSKSPFAVLDYSSPGGNELHRKIRNNLPDLPIKALDGIGGEYKVSNPFLTLQGTSYVLSLPGNRSQTISTNLLGSFNVRNTALAFLTGLGLGLDPKGMFSSLKEIPQIPGRFQIVYSKDRSRMAVVDYAHTPDALENIIRSVRNSRPKRLITLFGCGGDRDKTKRPKMARIAEELSDQVILTSDNPRSEKPEAILDEIQSGFSPGFTPLLREVDRARAISEGVGILPEGGCLLVAGKGHEEYQIIGKEKRHFSDVEEVRKAFGLF
What is the function of this protein?
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
What are the official names of this protein?
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase, Meso-A2pm-adding enzyme, Meso-diaminopimelate-adding enzyme, UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase, UDP-MurNAc-tripeptide synthetase, UDP-N-acetylmuramyl-tripeptide synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family. MurE subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ACCD_PELPB
Sequence: MAWFKRVKPSIRPTDKRDMPEGLWWKCEECGAMLHKKQFEDHFFTCAECGHHFRISPYKYFSILFDDDKYVEFDDHLRSADPLGFVDTKKYPDRVHDTIEKSGKTEACRNAHGESGGRPLVVSAMDFGFIGGSMGSVVGEKIARAVDKSLELDAPLLVISQSGGARMMEGAFSLMQMAKTAARLTRLSERKLPFVSLMTDPTMGGISASFAMLGDINISEPKALIGFAGPRVIRDTIKRDLPEGFQRAEFLLEQGFLDRVIHRRDLKNELVTLFSMLKV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NIFM_KLEOX
Sequence: MNPWQRFARQRLARSRWNRDPAALDPADTPAFEQAWQRQCHMEQTIVARVPEGDIPAALLENIAASLAIWLDEGDFAPPERAAIVRHHARLELAFADIARQAPQPDLSTVQAWYLRHQTQFMRPEQRLTRHLLLTVDNDREAVHQRILGLYRQINASRDAFAPLAQRHSHCPSALEEGRLGWISRGLLYPQLETALFSLAENALSLPIASELGWHLLWCEAIRPAAPMEPQQALESARDYLWQQSQQRHQRQWLEQMISRQPGLCG
What is the function of this protein?
Required for the activation and stabilization of the iron-component (NifH) of nitrogenase.  Probable PPIase.
What are the official names of this protein?
Putative peptidyl-prolyl cis-trans isomerase NifM, PPIase NifM, Rotamase NifM.
What is the protein family that this protein belongs to?
Belongs to the PpiC/parvulin rotamase family.
Protein: HBA2_ALDGI
Sequence: MVLTAGDKANVKTVWSKVGSHLEDYGSETLERLFVVYPSTKTYFPHFDLHHDSPQVRAHGKKVLSALGEAVNHIDDIPGALSKLSDLHAQNLRVDPVNFKLLNLCFVVVVGRHHPTILTPEVHVSLDKFLSAVAQNLTSKYR
What is the function of this protein?
Involved in oxygen transport from the lung to the various peripheral tissues.
What are the official names of this protein?
Hemoglobin A subunit alpha-2, Hemoglobin A alpha-2 chain.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: SLX4_YEAST
Sequence: MELQRAQRNLKFLQNEDYVNVTDQTNLNGESQNAYSLGMETQVPEMQFSLSSDDDSIGTQVKSVTAQKSPMTQETTKNDTERNKDVDKSCNPVSTSHPDLGGSNIEENIFINTQIQSRLDDAEEETNLKLKLEKFKYSFKSSNADDTHSNANVTAKRRPAIRKANSKLKTKPKTKRDPKIIKNITDFNINNYERSRTASLLKQLSGKHKKVLDIIKTQNEGNSDKPPRARNNKGEKATFDTYSEQEWKDIMKLLLQKFPQSEETDLNEVQKFLYGSEKSSNSLDNQESSQQRLWTASQLPPELPDEAIQPEQEERIRDTQSAVNFLSLSQVMDDKSEIMKDEESIIISRGDSTSSQEYGNGLEPQQPVGNVVGEDIELAVGTRINAFSLTDYKACKPMSVEVSRRCENSTDNDYDNISIVSDTTDETSTLFPLDQYRYVFIENDERPPLATDTIGSTQFFTPNTSPLDGIIDLTQESFKAVRSLISPLKVENNKTGVTSQASNQVQVPATRTPTIIPQKNLTTTLKTEEEKNNIGSSIRVKLLQESVVKLNPKLVKHNFYRVEANDSEEEETEFDDQFCIADIQLVDSSKISTKDSTQNPTTSNDIIDTSAASSIASPEKFCEIMMSQSMKELRQSLKTVGLKPMRTKVEIIQSLQTASQILSTANPDNKGEHGGVANFSKIEIFDHLTELIEAFPDFLERIYTFEPIPLNELIEKLFSAEPFVSQIDEMTIREWADVQGICLRNDKK
What is the function of this protein?
Regulatory subunit that interacts with and increases the activity of different structure-specific endonucleases.  Has several distinct roles in protecting genome stability by resolving diverse forms of deleterious DNA structures.  Component of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination.  Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.  Has a preference for simple Y, 5'-flap and replication fork-like structures.  It cleaves the strand bearing the 5'-non-homologous arm at the branch site junction and generates ligatable, nicked products from the 5'-flap or replication fork substrates.  Plays a critical role in maintaining the integrity of the ribosomal DNA (rDNA) loci, where it has a role in re-starting stalled replication forks.  Has Holliday junction resolvase activity in vitro.  Interacts with the structure-specific RAD1-RAD10 endonuclease and promotes RAD1-RAD10-dependent 3'-non-homologous tail removal (NHTR) during repair of double-strand breaks by single-strand annealing.  SLX4 also promotes recovery from DNA-alkylation-induced replisome stalling during DNA replication by facilitating the error-free mode of lesion bypass.  This does not require SLX1 or RAD1-RAD10, but probably RTT107.
What are the official names of this protein?
Structure-specific endonuclease subunit SLX4, Synthetic lethal of unknown function protein 4.
What is the protein family that this protein belongs to?
Belongs to the SLX4 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: YAAA_ECOSE
Sequence: MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPPQISTLMRISDKLAGINAARFHDWQRDFTPENARQAILAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALAAQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFFDEDSSSNGELVFKRYEQR
What are the official names of this protein?
UPF0246 protein YaaA.
What is the protein family that this protein belongs to?
Belongs to the UPF0246 family.
Protein: KHSE_VIBCM
Sequence: MSVVVYAPASIGNVSVGFDVLGAAVSPIDGTLLGDRVKVEAGAEAFTLKTAGRFVDKLPANPQENIVYDCWQVFARELEKKSVVLKPLTMTLEKNMPIGSGLGSSACSIVAALDALNQFHASPLDETELLALMGEMEGKISGSIHYDNVAPCYLGGVQLMLEELGIISQSVPSFDDWYWVMAYPGIKVSTAEARAILPAQYRRQDIVAHGRYLAGFIHACHTQQPELAAKMIKDVIAEPYREKLLPGFAKARNYAASAGALATGISGSGPTLFSVCKEQAVAERVARWLEQNYVQNEEGFVHICRLDKQGSKVTGSEL
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HBAT_HUMAN
Sequence: MALSAEDRALVRALWKKLGSNVGVYTTEALERTFLAFPATKTYFSHLDLSPGSSQVRAHGQKVADALSLAVERLDDLPHALSALSHLHACQLRVDPASFQLLGHCLLVTLARHYPGDFSPALQASLDKFLSHVISALVSEYR
What are the official names of this protein?
Hemoglobin subunit theta-1, Hemoglobin theta-1 chain, Theta-1-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: YBAJ_BACSU
Sequence: MNALVAHNSKAWDKKVETGNEWTVAVEQQVIEQAKKGNWDIRVTPMKDVPKDWFPPIKGLKVLCLASGGGQQGPVLAAAGADVTVLDNSEKQLNQDRMIAERDGLTIHTVKGSMDDLSVFNDESFDVIVHPVANVFVENVLPVWKEAYRVLKRNGILISGFVNPVVFLFDTELEQQGVLKVKHSIPYADPEDLPKHKVKKLIENNEALEFGHSLEDQIKGQIDAGFIVTGFYEDKGGFVLDQYIHTYSATRSVKV
What are the official names of this protein?
Uncharacterized methyltransferase YbaJ.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily.
Protein: YCF12_CYACA
Sequence: MLNWQVIVQLVFLALIITTGPVIIVYLSTRERNLL
What is the function of this protein?
A core subunit of photosystem II (PSII).
What are the official names of this protein?
Photosystem II reaction center protein Ycf12.
What is the protein family that this protein belongs to?
Belongs to the Ycf12 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: RL16_BRUA4
Sequence: MMQPKRTKFRKQFKGRIHGNSKGGTDLNFGAFGLKAVEPERVTARQIEAARRAITRHMKRAGRVWIRIFPDLPVTSKPTEVRMGKGKGSVDYWACRVAPGRVMFELDGVPEDVAREALRLGAAKLPIKTRFIQRIAE
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: MAX_RAT
Sequence: MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGGTISAFDGGSDSSSESEPEEPQNRKKLRMEAS
What is the function of this protein?
Transcription regulator.  Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'.  The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor.  May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.  Represses MYC transcriptional activity from E-box elements (By similarity).
What are the official names of this protein?
Protein max, Myc-associated factor X.
What is the protein family that this protein belongs to?
Belongs to the MAX family.
What are the subcellular locations of this protein?
Nucleus. Cell projection, dendrite.