PharMolix/UniProtQA huggingface dataset:
Protein: COA8_CAEBR
Sequence: MSSLSSSSSNVRMDRRFDWVGPPDSVSKIRKIMLRRVDNESELERQYRAAREELNQWNSDFWAEHNQLFDRQKSEFVEKKQKELGRLEHVSANELSEFYRDFLNDRHVAMMVYNKEWYRRNLQLIWPALKVNVVRFFRMARR
What is the function of this protein?
May be required for cytochrome c complex (COX) assembly and function, COX being the terminal component of the mitochondrial respiratory chain.
What are the official names of this protein?
COA8 family protein CBG23705, mitochondrial, COA8, APOPT family protein CBG23705, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COA8 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SYR_STRCO
Sequence: MASVTSLSDSVQQHLASALTATRPEAAGADPLLRRSDRADYQANGILALAKKTKANPRELAAEVVARITTGDELIEDVEVSGPGFLNITVADRAITANLAARLADGERLGVPLKQDAGTTVVDYAQPNVAKEMHVGHLRSAVIGDALRSMLDFTGEKTIGRHHIGDWGTQFGMLIQYLFEHPGELAPAGDIDGEQAMSNLNRVYKASRAVFDTDEEFKERARRRVVALQSGDKETLDLWQQFVDESKVYFYSVFEKLDMEIRDEEIVGESAYNDGMPETARLLEEMGVAVRSEGALVVFFDEIRGKDDQPVPLIVQKADGGFGYAASDLTAIRNRVQDLHATTLLYVVDVRQSLHFRMVFETARRAGWLGDEVTAHNMGYGTVLGADGKPFKTRAGETVRLEDLLDEAVQRAAEVVREKARDLTEDEIQERAAQVGIGAVKYADLSTSPNRDYKFDLDQMVSLNGDTSVYLQYAYARIQSILRKAGEVRPAAHPELALHEAERALGLHLDAFGPTVFEAAAEYAPHKLAAYLYQLASLYTTFYDKCPVLKAETPEQVENRLFLCDLTARTLHRGMALLGIRTPERL
What are the official names of this protein?
Arginine--tRNA ligase, Arginyl-tRNA synthetase, ArgRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EPN4_HUMAN
Sequence: MLNMWKVRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISKFRRKDREDSPERCSDSDEEKKARRGRSPKGEFKDEEETVTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKTSVPSSKSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGDWSAFNQAPSGPVASSGEFFGSASQPAVELVSGSQSALGPPPAASNSSDLFDLMGSSQATMTSSQSMNFSMMSTNTVGLGLPMSRSQNTDMVQKSVSKTLPSTWSDPSVNISLDNLLPGMQPSKPQQPSLNTMIQQQNMQQPMNVMTQSFGAVNLSSPSNMLPVRPQTNALIGGPMPMSMPNVMTGTMGMAPLGNTPMMNQSMMGMNMNIGMSAAGMGLTGTMGMGMPNIAMTSGTVQPKQDAFANFANFSK
What is the function of this protein?
Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).  May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes.  Stimulates clathrin assembly.
What are the official names of this protein?
Clathrin interactor 1, Clathrin-interacting protein localized in the trans-Golgi region, Clint, Enthoprotin, Epsin-4, Epsin-related protein, EpsinR.
What is the protein family that this protein belongs to?
Belongs to the epsin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin- coated vesicle. Note=Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
Protein: LIN54_DANRE
Sequence: MDVVSPELNSLLPDEIMDTEAMDEDPPASHLTPPPQSAPESAQVPMETEVPEIISICPTTASMQAISTNAKSTTSSTTQLLLTPSSSSSTTTKNATPTLPKIPSLSVPPNHQLIINKVAADGKSPGGAVIKQEGQKLLVAGLSKTGQPIMLALPHAWNKPATSQGSGDAKSQPTQIKMVTAMGKPVIAVSSASQLVASSTPLQAQHLKTLQITKKPPVSTAGPMITKLIITKALNNKVLSSPGSVSPVVTGRVVSQSTPLTPPRTIAIGETISTVPQNAATNSKVAISPLKSPSKLTVVSVTSQSSNSPQKSMTLPLNVALGQQILTVQQSAVTSPAKAGSSQSTTQTVKPVQTVTVPTSQFKTIIPLTTPPNVQQIQVPGSRFHYVRLVTATTGSSTVQTGGSTNTNPSIQPAKPVMMNAAVRMSVPIVPAQTAKQVVPKPLSSAAQVVTTSQTPQRLIMPATHLPQIQPNLTNLPPGTVLAPAHGSGNVGYAVLPAPYVTQIPQPAFVTLTSSSTFSTATPSQAQARLSLNGLSTSEANSRPRKPCNCTRSQCLKLYCDCFANGEFCNNCNCVNCFNNLDHESERLKAIKACLDRNPVAFKPKIGKGKEGESDRRHSKGCNCKKSGCLKNYCECYEAKIMCSSICKCMGCKNFEESPERKTLMHLADAAEVRVQQQTAAKTKLSSQISDLLTRTTPAITSGGGKLPYTFVTKEVAEATCDCLLEQAEQAELTNQPQAMAERLILEEFGRCLHRIISFAGKAKTDCPINC
What is the function of this protein?
Component of the DREAM complex, a multiprotein complex that can both act as a transcription activator or repressor depending on the context.  Specifically recognizes the consensus motif 5'-TTYRAA-3' in target DNA.
What are the official names of this protein?
Protein lin-54 homolog.
What is the protein family that this protein belongs to?
Belongs to the lin-54 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MURI_MYCLE
Sequence: MSSPLLPVGVFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLSIPEIRAHALAICDDLVGRGVKILVIACNTASAACLRDARERYDVPVVEVILPAVRRAVAATRNGRIGVIGTRATIASHAYQDAFAAARDTEITAVACPRFVDFVECGVTSGRQVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLAGLIQLAMGENVTLVSSAEETAKEVLRVLTERDLLRRHDAPPVNRVFEATGDPEAFIQLAARFLGPAVSGVQPARLHSRVR
What is the function of this protein?
Provides the (R)-glutamate required for cell wall biosynthesis.
What are the official names of this protein?
Glutamate racemase.
What is the protein family that this protein belongs to?
Belongs to the aspartate/glutamate racemases family.
Protein: Y600_BACAA
Sequence: MSIKYSNKINKIRTFALSLVFIGLFIAYLGVFFRENIIIMTTFMMVGFLAVIASTVVYFWIGMLSTKTVQIICPSCDKPTKMLGRVDACMHCNQPLTMDRDLEGKEFDEKYNKKSYKS
What are the official names of this protein?
UPF0295 protein BAA_0600.
What is the protein family that this protein belongs to?
Belongs to the UPF0295 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: HEM6_RAT
Sequence: MALRLGQLGSGPWWRAVRGDYAQLRAPSPRSASACVCRLPGTAGTQPRRGLGHGSSAGGGSRLGTGLAAALAGMAGLAAAVLGHVQRAEMVPKSSGARSPSPGRLEEDGDELARRCSTFMSSPVTELRELGRRPDDMKTKMELMIMETQAQVCRALAQVDGVADFSVDRWERKEGGGGITCVLQDGRVFEKAGVNISVVHGNLSEEAANQMRSRGKALKKKDGKLPFTAMGISSVIHPKNPYAPTMHFNYRYFEVEEADGKMHWWFGGGCDLTPTYLNREDAVHFHRTLKEACDQHGPDIYPKFKKWCDDYFFIAHRGERRGIGGIFFDDLDSPSKEEAFRFVKTCAEAVVPSYVPIVKKHCDDSYTPQDKLWQQLRRGRYVEFNLVYDRGTKFGLFTPGSRIESILMSLPLTARWEYMHSPPENSKEAEILEVLRHPKDWVH
What is the function of this protein?
Involved in the heme biosynthesis.  Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX (By similarity).
What are the official names of this protein?
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial, COX, Coprogen oxidase, Coproporphyrinogenase.
What is the protein family that this protein belongs to?
Belongs to the aerobic coproporphyrinogen-III oxidase family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: LPP2_SALPA
Sequence: MNRTNKLILGAVVLGSALLAGCSSNAKIDQLSSDVQTLSAKVDQLSNDVNAMRSDIQAAKDDAARANQRLDNKVSRVRK
What is the function of this protein?
A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes.  The only protein known to be covalently linked to the peptidoglycan network (PGN).  Also non-covalently binds the PGN.  The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane.
What are the official names of this protein?
Major outer membrane lipoprotein Lpp 2, Braun lipoprotein 2, BLP 2, Murein lipoprotein 2.
What is the protein family that this protein belongs to?
Belongs to the Lpp family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor; Periplasmic side. Secreted, cell wall; Peptidoglycan-anchor. Note=Attached via its lipidated N- terminus to the inner leaflet of the outer membrane. Attached to the peptidoglycan network (PGN) via its C-terminus.
Protein: RL23_SHEPA
Sequence: MISEERLLKVILAPHISEKSTVNAEKNNTVVFRVAIDATKAEVKAAVAQLFEVEVDSVRTLVNKGKTKRTGARVGRRSDWKKAYVTLAEGADIDFVGGAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL22_DROME
Sequence: MAPTAKTNKGDTKTAAAKPAEKKAAPAAAAAKGKVEKPKAEAAKPAAAAAKNVKKASEAAKDVKAAAAAAKPAAAKPAAAKPAAASKDAGKKAPAAAAPKKDAKAAAAPAPAKAAPAKKAASTPAAAPPAKKAAPAKAAAPAAAAPAPAAAAPAVAKPAPKPKAKAAPAPSKVVKKNVLRGKGQKKKKVSLRFTIDCTNIAEDSIMDVADFEKYIKARLKVNGKVNNLGNNVTFERSKLKLIVSSDVHFSKAYLKYLTKKYLKKNSLRDWIRVVANEKDSYELRYFRISSNDDEDDDAE
What are the official names of this protein?
60S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL22 family.
Protein: UFL1_DROVI
Sequence: MSSDWDEIKRLAADFQKAQLTSTLQKLSERNCIEIVTLLLEKQLLDVVFTNDGKEYITPDHLEREIQDELYANGGRANLVEVSKTLNVDLSRIVTLAERIAAENPHIHLLLGQLIDEDYITHIAQEINEKLAQHGEISISDLTSQFDLPSDFLQQNVVEKHLGKIIKGRQDASNPRVFFTQAYIQRCKAKIRGALAAITKPTNVAVILQQINVQEKIFHSLLDEISPAGQVTSKQANAQYVPHIYAKTQADWVNSFYKQNSFLEYEAINKLGISDAKTYIRNQFPNEQFLFLKRVALGARLIELTVVSALNECSATKHYLDLSTILPSNLSEEDIAEAFDAVIAQKHCNPSHFVYLESIVFSQAYLTELVQPCHDMALALAKSAIDNGVYQQYIVEKTLAQKGNNLSTSHDADDDSKTDKRDERRRKAASGKAGGGAQGRETKTKSTKKHQRGRAAAHNHDSEDEEDTVQQSAGNTRKSVKALELVKSSDIINLIKITLEEEGLEHLAKPIAALYLNQLNQVALSKAQELYEATPQTNRRQTHAAIQERVNMLLVDIRLYEKGLKLFHADTQTQLVKYLLKSLGNEICNELTLYVAAECSLSVKSTNLNVDQRIKLIQELDAQYRNALLEQNKALNRSIEDFELATESVLKACSMIIKKADKKKDRALIIGHKEKLLQQLLECHEPALLLHLAALILFTTITGCILHASGKFVSAILQHIRASLNEPQNALYLVLQMLQQATPDSAESKSINEQLQSLQAEVVDLAQNYSRASVSKAD
What is the function of this protein?
E3 UFM1-protein ligase that mediates ufmylation of target proteins.
What are the official names of this protein?
E3 UFM1-protein ligase 1 homolog, E3 UFM1-protein transferase 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the UFL1 family.
Protein: DTDA_DESA1
Sequence: MIGLVYSVEDPAGRGIASYIVEALKPHRTTNPYAMEYYEGDGFVLAGFNEDVIYFDFLEERLPMVSEYIVLSRHSSKAGVKSYTVHHTGNYGGEALSGGRPGELGIASPRTAWLLLRLLKTYRDAYSRNEYEVSYEATHHGPTSLSKPLVFIEIGSGLDEWRNRVNHAVVGDTVIGFLRGGIRDECIPVIGIGGGHYPRKHTELALAEPVCYGHIMAKYALEYMSRVVLDKMTERSVVKPVEVIVEKKGTRQEHRSLLEEYVSEKKLSLRYI
What is the function of this protein?
D-aminoacyl-tRNA deacylase with broad substrate specificity.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, D-tyrosyl-tRNA(Tyr) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DtdA deacylase family.
Protein: RS19_STRE4
Sequence: MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR
What is the function of this protein?
Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S19.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: ATGT_THEAC
Sequence: MKIEERDGLARIAKFETPHGPIETPTVLPVINPNIMNITPQEMKPLGLQGIITNSYIILRTPELRERALREGLHSLIGYDGPIMTDSGTFQSYVYGSIEFNNREVVDFQRRIGSDISTILDVFTTPGTPKPEAEKAVIETYNRMLEVNDEEGIIAGPVQGGVYPDLRQKSAELMNSTNAGYHPIGGVVPLLETYDYSTLVDIIINSKINLSFNKPVHLFGGGHPMFFAFSVYLGVDLFDSASYIKYAKDDRLIYPDGTRDLARITELPQWSPLYDRYTVKEIRDLDKERRSLEIARHNLKAIFMEISEIKERIYEEGLAQYVAQKARSHPSLMKAYSRIMSYSNILEKYEDLSKKTAYFFYDSFSTRNPYVSRINRFTESYLSSNKKDTYAFTYRAWNPGYTNSEFVRDVYQKIDCNALISWSGTFVPAELENTYPIEQTVSSGFEPDPDFSRAKDLIAPFRVDMYKGEKFEGEQVRSFNLNKIRMVADYQFGSGVGRMIFRDDVRINVSKTGRIRGILSKEGRQIATMRNDGFFTLTYYGASLIHSQLKPPAMRVTVSKESAEYNAKGYSVFFKFILGSDENIIAKNDVLVVDEDDVLAAVGKAMVSGRELREYTEGIAVKVHEGRDQSEK
What is the function of this protein?
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
What are the official names of this protein?
tRNA-guanine(15) transglycosylase, 7-cyano-7-deazaguanine tRNA-ribosyltransferase, Archaeal tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the archaeosine tRNA-ribosyltransferase family.
Protein: ALBA2_SACSH
Sequence: MTEKLNEIVVRKTKNVEDHVLDVIVLFNQGIDEVILKGIGREISKAVDVYNSLKDRLGDGIQLVNVQTGSEVRDRRRISYILLRLKRVY
What is the function of this protein?
Binds double-stranded DNA tightly but without sequence specificity.  It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture.  However, it does not significantly compact DNA.  Binds rRNA and mRNA in vivo.  May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity).
What are the official names of this protein?
DNA/RNA-binding protein Alba 2.
What is the protein family that this protein belongs to?
Belongs to the histone-like Alba family.
What are the subcellular locations of this protein?
Cytoplasm. Chromosome.
Protein: FABH_ALIF1
Sequence: MYSKILGTGSYLPAQIRSNADLEKMVDTSDEWILARTGISERRIAGEDESVATMAHLASVNAIEMAGIDKNDIDLIILATSTPTYSFPSAACEVQGLLGIQGCPAFDLSAACSGFVYALSVADQHIKTGMAKNVLVIGSDAVSHTCDPEDRSTIILFGDGAGAVVLGQSEEPGIISTHLHADGKFGELLSLPVPSRKNEEADKWLYMAGNEVFKVAVTQLSNLVKETLQENQMDKSELDWLVPHQANLRIIKATAKKLSMSMDQVVVTLDRHGNTSAATVPTALDEAVRDGRIQRGQTLLLEAFGGGFTWGSALVKF
What is the function of this protein?
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.  Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production.  Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities.  Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
What are the official names of this protein?
Beta-ketoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III, 3-oxoacyl-[acyl-carrier-protein] synthase 3, 3-oxoacyl-[acyl-carrier-protein] synthase III.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. FabH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HUTH_BACC3
Sequence: MITLTGHTLTIEEMKRLLLEGEGVTACPNSMQKVAECREVVEKIVEDGKVVYGITTGFGKFSDVLIQKDDVKALQHNLIQSHACGIGDPFPEEVSRGMLILRANTMLKGVSGVRPLVVNMLLEFVNRKIHPVVPQQGSLGASGDLAPLSHLALVLLGEGEVFYKGKRVHAMVALTEEGLEPIELEAKEGLALINGTQAMTAQGVLSYIEAEATSYQAELIASMTIEGLQGIIDAFDENVHKARGYKEQVEVASRIRDILHDSKLTTKQGELRVQDAYSLRCIPQVHGASWQVLNYVKEKLEIEMNAATDNPLIFDGGEKVISGGNFHGQPIAFAMDFLKVGMAELANISERRIERLVNPQLNDLPPFLSPEPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHAHQIIQNVRRVLSVEMICAMQAAEYRGIENMSTVTKSFYHQGRQQVPSITNDRIFSTDIENITHWLKTNYSIKERLDVNAAL
What are the official names of this protein?
Histidine ammonia-lyase, Histidase.
What is the protein family that this protein belongs to?
Belongs to the PAL/histidase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TLP12_PHONI
Sequence: QKKDKKDKFYGLF
What are the official names of this protein?
Tachykinin-like peptide-XII, P.nigriventer tachykinin peptides XII, PnTkP-XII, U29-ctenitoxin-Pn1l, U29-CNTX-Pn1l.
What is the protein family that this protein belongs to?
Belongs to the tachykinin family.
What are the subcellular locations of this protein?
Secreted.
Protein: HEMH_FRATF
Sequence: MQQYSSKYNKQAILLVNLGTPDNYDTKSIKRYLKEFLSDPRVIEANPILWKIILNLIILPIRAKKNIHTYKTVWNKQHNKSPLLFYTENLADKLDKKLDNYIVDYAMRYGNPSIESKIKSLQDQGATEIIIFPLYPQYSATTATVYDEVYRVLSKLRWQPTIKGINPYYDNKFHIQTISQQIKEHLKKLDSTPDTVLFSFHGLPKEYFDKGDPYYCHCYKTYRLVKEELQNEYPNIDFELSFQSRFGPKKWLEPYTTVKLEEFAKQNKSVVIIAPGFSADCLETLEELAISEKENFIKKGGKEFSLIPCLNDSNQHVDMLYNIIDEEICLKK
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OBG_NITEU
Sequence: MKFIDEVKIQISAGDGGNGVASFRREKFIPRGGPDGGDGGHGGSIYALADHNLNTLIDYRFTPVFRAKRGENGRGSDCYGKGAEDIVLRMPVGTIITNDLTGELVADLEHDQQKVLLAKGGRGGLGNLHFKSSTNRAPRQFTHGEAGEQFELRLELRVLADVGLLGLPNAGKSTLIRAVSAARPKVADYPFTTLYPNLGVVRVDAGHSFVMADIPGLIEGAAEGAGLGHRFLKHLGRTRLLLHVIDVAPFDENVDIVHSARALVDELRKFDETLYRKPRWLVFNKVDMLPEDEQQAVCTRLLQAMNWQERWFAISALTGRGCQALIYAIMGHLQQLQSDSEET
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ESPB_MYCTO
Sequence: MTQSQTVTVDQQEILNRANEVEAPMADPPTDVPITPCELTAAKNAAQQLVLSADNMREYLAAGAKERQRLATSLRNAAKAYGEVDEEAATALDNDGEGTVQAESAGAVGGDSSAELTDTPRVATAGEPNFMDLKEAARKLETGDQGASLAHFADGWNTFNLTLQGDVKRFRGFDNWEGDAATACEASLDQQRQWILHMAKLSAAMAKQAQYVAQLHVWARREHPTYEDIVGLERLYAENPSARDQILPVYAEYQQRSEKVLTEYNNKAALEPVNPPKPPPAIKIDPPPPPQEQGLIPGFLMPPSDGSGVTPGTGMPAAPMVPPTGSPGGGLPADTAAQLTSAGREAAALSGDVAVKAASLGGGGGGGVPSAPLGSAIGGAESVRPAGAGDIAGLGQGRAGGGAALGGGGMGMPMGAAHQGQGGAKSKGSQQEDEALYTEDRAWTEAVIGNRRRQDSKESK
What are the official names of this protein?
ESX-1 secretion-associated protein EspB, Antigen MTB48.
What are the subcellular locations of this protein?
Secreted. Note=Secreted via the ESX-1 / type VII secretion system (T7SS).
Protein: COXX_CUPNH
Sequence: MVTATHPHSLGKLSRIRHLARQYAALTKPRVTQLAVFCAIIGMFLATPGMVPWRVLIGGAAGIWLLAGAAFAINCLVEQKIDALMRRTAWRPSATGEITTPQTLVFSAILGGAGMWLLHVYANDLTMWLTFATFLGYAVVYTILLKPATPQNIVIGGLSGAMPPALGWAAVAGEVPAEAWFLVLIIFTWTPPHFWALALYRRADYAKSGLPMLPVTHGERYTLLHILLYTLIMIAATLLPFVYGMSGYIYLAAALALGAGFLAYAWKMYRNYSDELAQRAFRFSILYLSLLFAALLVDHYFKFVPQV
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: MNMG_SYNS3
Sequence: MSFSPPPTEVFDVIVVGGGHAGCEAAITAARLGLSTALFTLNLDRIAWQPCNPAVGGPAKSQLVHEVDALGGVIGRLADATAIQKRVLNASRGPAVWALRAQTDKRHYSREMLQLLHHTPNLALREAMVTGLEVDGDPEPAGQARITGVRTYFGSVYGAQAVVLTAGTFLGGRIWVGHQSMSAGRAGEQAAEGLTDALKQLGFQTDRLKTGTPARVDRRSIALDQLEAQPSDAADRFFSFDPTAWASGEQMSCHITRTTAATHQLIKDNLHLTAIYGGIIDSKGPRYCPSIEDKIVRFADKDSHQIFLEPEGRDTPEIYVQGFSTGLPETIQLELLRTLPGLEQCVMLRPAYSVDYDYLPATQLKPSLETKRVRGLFSAGQLNGTTGYEEAAAQGLVAGLNAARLIGGQEPVHFPRENSYIGTMIDDLVSQDLREPYRVLTSRSEYRLVLRGDNADRRLTPLGRELGLIDDRRWQLFNDKLQAMEEEKQRLETVRLKVSDPVASTVEKESGAPIRGSITLADLLRRSGVHSSDLVRHRLADAELPLAVREGAEIDIKYSGYLQRQQQQIDQVKRQSLRKLPADLDYASIGTLSREAREKLTAIQPTTLGQATHIPGVSQADLTALLLWLELQKRRSQKSESLASSTNSR
What is the function of this protein?
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
What are the official names of this protein?
tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, Glucose-inhibited division protein A.
What is the protein family that this protein belongs to?
Belongs to the MnmG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VFIL_BP186
Sequence: MLKSEPSFASLLVKQSPGMHYGHGWIAGKDGKRWHPCRSQSELLKGLKTKSPKSSGFLIIRIVHFVIKGVKHVTR
What is the function of this protein?
This protein causes filamentation.
What are the official names of this protein?
Protein fil.
Protein: TBA1B_CRIGR
Sequence: MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY
What is the function of this protein?
Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers.  Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms.  Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
What are the official names of this protein?
Tubulin alpha-1B chain, Alpha-tubulin 1, Alpha-tubulin I, Tubulin alpha-1 chain.
What is the protein family that this protein belongs to?
Belongs to the tubulin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: RL7_LEGPH
Sequence: MAVSKNEILETISNMTVMEVVELIEAMEEKFNVSAAAAAVAVAAPAAGAGAAAAEEQTEFTVVMTSFGSNKVNVIKAIRGITGLGLKEAKDLVEGAPSTVKEGVSKDEAASIKKELEEAGATVEVK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation.
What are the official names of this protein?
50S ribosomal protein L7/L12.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: Y1265_HAEIN
Sequence: MTEQTFILGKDAALEDSIAKFQQKLTALGFNIEEASWLNPVPNVWSVHIRDKDCPQCFSNGKGASKKAALASALGEYFERLSTNYFFADFYLGQEIANSDFVHYPNEKWFPIEDDALLPNGILDDYLLDYFBPNAELTPELLVDLQSGNYDRGIVAMPYVRQSDEQTVYIPQSIIANLYVSNGMSAGNTKFEARVQGLSEVFERYVKNKIIAEAISLPEIPKSVMDRYPSIQASIAKLEEEGFPIYAFDASLGGKYPVICVVLLNPNNGTCFSSFGAHPNFQVALERTVTELLQGRSLKDLDVFSPPSFNNDDVAEHANLETHFIDSSGLISWDLLKETPDYEFADWDFSGTTQEEYNNLMAIFRADEKEVYVMDYNHLDVYACRIIVPGMSDIYPADDLIYANNNMGMDWREILLDLPNWHHDAETYQELLEELDGQDIDDATRVREFIGIVAPKNSGWTTLRVGELKSMLHLALGELEQALDWANWTLNMNSSVFTTEPVNYYRTLISIIELHLDQNRDPAQYRAVFEKMYGKDAVKQAWAAVSEGGNPFYNLPASDENLKNFKEHQALLGAYGKLQKAKKENWK
What are the official names of this protein?
Uncharacterized protein HI_1265.
Protein: HIS1_DICT6
Sequence: MIRIAIPTGRMLEQTLDFLRNFDKKLLDEEKGRKLRIRGERFEVFLAKPWDLPLYVEERVVDLGIIGRDVILEQERNLVNLLSLPFGYCKMVIAGYPHISLEKNGKEIKIATKYENIARKFLEDKWSKIKVIKLNGSVELGPILNISDFIVDIVETGKTLKENGLEIKEVLFESSACLVSNVASFVYLRDEILSFVKEVRKLNDKCN
What is the function of this protein?
Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP).  Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
What are the official names of this protein?
ATP phosphoribosyltransferase, ATP-PRT, ATP-PRTase.
What is the protein family that this protein belongs to?
Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS18_PSEFS
Sequence: MARFFRRRKFCRFTAEDVKEIDYKDLNTLKAYVSETGKIVPSRITGTKARYQRQLATAIKRARFLALLAYTDSHGR
What is the function of this protein?
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S18.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.