PharMolix/UniProtQA huggingface dataset:
Protein: LTV1_DROME
Sequence: MVKGKKPYIDRKKAVTFHLVHRSQHDPLVTDENAPQRVLLEAAARQQKPKDPEPPTDPAQRQEELKKFGIHFDDDYDYMQHLKKRENDVVWEFMENPNQARKQKVQDSEKPGPAPKLMLPSSVFASEFEESEGMLNKAAPQTLRLDWDPDVVAALDSDCENEELEDDFVIQAMAEGDSDDEEWDDEDGEEQSDMDFDSDDLNEDENEDELMDRLAPLMRERRFDDEEVKSRFTEYSMSSSVIRRNEQLSLLDDRFEKFYATYDDPELGDLALEDIEGNWHQKHPVVMQCFQEFKKKDKGIEYNKEWDRERIEKYRNVVEGEEDPTEELVEYEVDDPKQKKWDCESILSTYSNIYNHPKVIDEPRRSRRSSASTNPAPIQIDPKTGLPTNVLRGGVDGQLTAKALANLADESPAATGPKSLCAKSVLSTLSVLSIRPKDETHEEKKERKRLLKDYRNERRIEKKANTEAFKEEKKRQTHVKINQRTNQQGASIV
What is the function of this protein?
Necessary for the biogenesis of 40S ribosome subunits by regulating pre-rRNA processing.  Non-ribosomal factor required for efficient nuclear export of the ribosomal 40S subunit.  Necessary for endoreplication driven by Myc.
What are the official names of this protein?
Protein LTV1 homolog, Low temperature viability protein 1, Ribosome biogenesis factor LTV1.
What is the protein family that this protein belongs to?
Belongs to the LTV1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEF_OCEIH
Sequence: MVGRDENELQDVQLLGSQGTTYDFNYTPEVLEVFDNKHVSRDYFVKFNCPEFTTLCPKTNQPDFGTIYISYIPDIKMVESKSLKLYLFSFRNHGDFHEDCINIIMNDLIDLMNPRYIEVRGKFTPRGGISIDPYCNYGRPGTKFEQMADQRLIQHDMYPEKIDNR
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
What are the official names of this protein?
NADPH-dependent 7-cyano-7-deazaguanine reductase, 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_STRPZ
Sequence: MFVKKGDKVRVIAGKDKGTEAVVLKALPKVNKVIVEGVGMIKKHQKPNTENPQGAIVEKEAPIHVSNVQVLDKNGVAGRVGYKVVDGKKVRYSKKSGEVLD
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: MAC2_PSEA3
Sequence: MTTEDNQRWSQVSPDLAKRPLVGVEKVLNYTEYYQNGNFQLTIALLFETSVASETLCERFPLALWSVRSKLPELGTSTVSNDQSAELDLDHALWQPIRSLEQAQQWLDDTGVIVNDGTSVQQMVDRLSNRRIEPIGKQFRVYLVCDPLYGAPGLIVNASHVLNGHRALFQGESIFKALLSPRISDATRQNPDAKAALAAIFKPEELNEALPKLPQSLNTAYADKFQPGAPEIEAGFHKVGEKLSNGAQPSIGIPRFQIPSAKPAFSLGSLDGTPMSMLNLRSRINAADNQSLKRACKKYGASVPSLVYACIVNSIDRHCGSSSSEAVLGANLAYSAHASRWMPAETFEERSPVNMAIVLGSGYLSPEELQPGQRGRNLGEAGLFALARTIRKKQDDFLDTPHIIGAMSDLGEQVSSQLAEVAERQREAGTDARVALSENSPLVCPPTLTSQGVITVKRFYTAQGASDELHLEQPADEHLEFFDICTGGRTTDASVCFAMFTHVGALTLQAHFDSHFFDAQLVRNILDDVVSQLGSAAASASLTSQDQAKL
What is the function of this protein?
Acyl-CoA-dependent acyltransferase; part of the gene cluster that mediates the biosynthesis of mannosylerythritol lipids (MELs), surface-active substances that enhance the availability of water-insoluble substrates (Probable) (PubMed:20564650, PubMed:31923270).  Depending on the number of acetyl groups, mannosylerythritol lipids can be differentiated into MEL A (fully acetylated), MEL B and MEL C (monoacetylated at R-6 and R-4, respectively), and the fully deacetylated MEL D (By similarity).  The first step in the pathway is the generation of mannosylerythritol by the glycosyltransferase EMT1 which catalyzes the transfer of GDP-mannose to the C-4 atom of meso-erythritol (Probable).  This reaction has to be stereospecific, since only mannosyl-D-erythritol is generated (Probable).  The produced disaccharide is subsequently acylated with fatty acids of various lengths by the acyltransferases MAC1 and MAC2 at positions C-2 and C-3, repectively (Probable).  The existence of MEL derivatives which carry an acetyl group at C-2 implies that at least MAC1 also accepts acetyl-CoA as a donor (Probable).  The final step of MEL biosynthesis is the acetylation of the fully acylated mannosylerythritol lipids catalyzed by the acetyl-CoA-dependent acetyltransferase MAT1 (Probable).  MAT1 displays a relaxed regioselectivity and is able to transfer acetylgroups to both positions C-4 and C-6 of the mannosyl moiety (Probable).
What are the official names of this protein?
Acyl-CoA-dependent acyltransferase MAC2, Mannosylerythritol lipids (MELs) biosynthesis cluster protein MAC2.
What is the protein family that this protein belongs to?
Belongs to the trichothecene O-acetyltransferase family.
Protein: SH3L2_PONAB
Sequence: MVIRVFIASSSGFVAIKKKQQDVVRFLEANKIEFEEVDITMSEEQRQWMYKNVPLEKKPTQGNPLPPQIFNGDRYCGDYDSFFESKESNTVFSFLGLKPRLASKAEP
What are the official names of this protein?
SH3 domain-binding glutamic acid-rich-like protein 2.
What is the protein family that this protein belongs to?
Belongs to the SH3BGR family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RS10_ECOL5
Sequence: MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG
What is the function of this protein?
Involved in the binding of tRNA to the ribosomes.
What are the official names of this protein?
30S ribosomal protein S10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS10 family.
Protein: SLYA_CALRH
Sequence: GLEDCDFGWSPYDQHCYQAFNEQKTWDEAEKFCRAQENGAHLASIESNGEADFVSWLISQKDELADEDYVWIGLRAQNKEQQCSSEWSDGSSVSYENLIDLHTKKCGALEKLTGFRKWVNYYCEQMHAFVCKLLPY
What is the function of this protein?
Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2).  Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation.  Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial.
What are the official names of this protein?
Snaclec rhodocytin subunit alpha, Aggretin alpha chain, Rhodoaggretin subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the snaclec family.
What are the subcellular locations of this protein?
Secreted.
Protein: AUR25_RANRN
Sequence: GLFDIVKKVVGAFGSL
What is the function of this protein?
Amphipathic alpha-helical antimicrobial peptide with moderate to potent activity against Gram-positive bacteria, Gram-negative bacteria and fungi (PubMed:10951191, PubMed:19056250, PubMed:23841919) (By similarity).  Shows also a weak activity against biofilm of both Gram-positive and Gram-negative bacteria (PubMed:19056250).  Probably acts by disturbing membrane functions with its amphipathic structure (PubMed:10951191, PubMed:23841919).  Kills fungi via membranolytic action (By similarity).  Enhanced sterol levels in lipid composition membranes reduce interaction of this peptide with membranes, having a protective effect against the lytic ability of the peptide (By similarity).  Shows anticancer activity (PubMed:10951191).
What are the official names of this protein?
Aurein-2.5.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Aurein subfamily.
What are the subcellular locations of this protein?
Secreted. Target cell membrane. Note=Contact and insertion into membrane begin at the N-terminus.
Protein: SIR2A_DICDI
Sequence: MYAVNPIECIHLKDEYDTCINKSIFDKDLKITKCHACNDESENWICMTCGVVSCSRHVNGHAGEHFENTKHPISASFSDHSFWCYTCDTYVHNTPLFDICEILENIKSSNKKDKIVPKKDQKEEEEEDQVVPSASITTSSTTTSISKQTTVNNTTTTSSSSTTTTTTTTSTTINNNEEEEESESETDESSSEGEESLSLIQRMREMIFGVGRGPKIVAPSEQEESEEDESCVLKKPTIEEIAKYINSAKCKNIIVMTGAGISVAAGIPDFRSPKTGLYEKLDKYDLPYREAIFDIEYFKKNPKPFYVLSKELFPGSFNPTTVHYFIKLLSDKGLLLRNFTQNIDTLERIAGIPANKLVEAHGSFATSHCVSCKKEYSTEYVKERIFKDELPECTETSGCKGIVKPDIVFFGESLPSRFNDCAREDFTKCDLLLVIGTSLKVHPFASLINFAKGCPRVLINFEEVGTNPYGGFKFNQPSNKLDVKCIGDCQTLVLDLIKLLGWENEFNQIVKN
What is the function of this protein?
NAD-dependent deacetylase, which plays an important role in the regulation of transcriptional repression.
What are the official names of this protein?
NAD-dependent deacetylase sir2A, Silent information regulator sir2A.
What is the protein family that this protein belongs to?
Belongs to the sirtuin family.
Protein: Y3065_LEGPA
Sequence: MTQEKGKFAEQLALNYLKENGLALVMQNYHCRLGEIDLIMREGSYLVFIEVRSRSNMNFGGGLASITYEKKQKIIKATSHYMIKYRIQDKFPIRFDVISIDGKSNKITWLKNAFDAGC
What are the official names of this protein?
UPF0102 protein lpp3065.
What is the protein family that this protein belongs to?
Belongs to the UPF0102 family.
Protein: AZOR_CROS8
Sequence: MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPVPVLDGELVGALRPSDAPLTPRQQDALSLSDELIAELQAHDVIVIAAPMYNFNIPTQLKNYFDLVARAGVTFRYTEKGPEGLVTGKRAIVLTSRGGIHKDTPTDLVTPYLSLFLGFIGITDVNFVFAEGVAYGPEMATKAQSDAKAAIDALVSA
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase, Azo-dye reductase, FMN-dependent NADH-azo compound oxidoreductase, FMN-dependent NADH-azoreductase.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: MGSA_CLOD6
Sequence: MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDETELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYHVPIATNLASAEIFIKALDRGELSWREVRKSKSQRI
What is the function of this protein?
Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.
What are the official names of this protein?
Methylglyoxal synthase, MGS.
What is the protein family that this protein belongs to?
Belongs to the methylglyoxal synthase family.
Protein: NDUA1_MOUSE
Sequence: MWFEILPGLAIMGVCLVIPGVSTAYIHKFTNGGKEKRVARVQYQWYLMERDRRISGVNRYYVSKGLENID
What is the function of this protein?
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone.
What are the official names of this protein?
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1, Complex I-MWFE, CI-MWFE, NADH-ubiquinone oxidoreductase MWFE subunit.
What is the protein family that this protein belongs to?
Belongs to the complex I NDUFA1 subunit family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein; Matrix side.
Protein: PF2R_RAT
Sequence: MSINSSKQPASSAAGLIANTTCQTENRLSVFFSIIFMTVGIVSNSLAIAILMKAYQRFRRKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSVFGISMVFSGLCPLFLGSTMAIERCIGVTNPLFHSTKITSKHVKMILSGVCMFAVFVALLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSSLGLLALGISFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMVIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKENQQASSEAGL
What is the function of this protein?
Receptor for prostaglandin F2-alpha (PGF2-alpha).  The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.  Initiates luteolysis in the corpus luteum.
What are the official names of this protein?
Prostaglandin F2-alpha receptor, PGF receptor, PGF2-alpha receptor, Prostanoid FP receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: SYFA_PARD8
Sequence: MLDKIKALLQEVENMKAANAEELEALRIKYLSKKGEISALMNDFRNVAADQKREVGKYLNELKETTQSKINELKESFENVQTANDDIDLTRTAYPIELGTRHPLSLVKKEICDIFGRLGFSIAEGPEIEDDWHVFSSLNFAEDHPARDMQDTFFIQHNPDVLLRTHTSSVQTRVMEKQEPPIRIICPGRVYRNEAISYRAHCFFHQVEALYVDKNVSFADLKQALLFFAKEMFSPDTKIRLRPSYFPFTEPSAEMDISCNICGGKGCPFCKGTGWVEILGCGMVDPNVLENCGIDSKVYSGYALGMGIERITNLKYQVKDLRMFSENDVRFLRQFESAN
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF_GLUDA
Sequence: MTRFDPFFQTALDDLDRRHLKRVLSPVDRDGPVIVRRDGASLLDFSSNDYLGLSHHPALRARAIDWTERFGIGSGASRLVTGTSEQYRQVEARLARFKGTEAALLLASGWQANAAVLPALLRISAAQTGEPALVFTDRLNHASLHHGCQAAGVRQIRFAHNDLGHLEHLLAQRQAQRGLRFIVTESVFSMDGDRADVAGLRTLADRYGAFLYLDEAHATGVLGPQGRGLSAEAGGVDLAMGTFSKALGGFGAYVAGSRAVCDWLVSTCSGFIYTTALPPGVLGVIDAALDLVPTLDAERAHLAGLADRMRAGAGALGWSTGPSSTQIVPVIVGAADRALTLARALAARGMLGTAIRPPTVPAGSARIRVALSAAHDETMVDRLLSALEDAAREHGIAP
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: TRUB_PROM0
Sequence: METKDGFLVINKDKGCTSHDCVKQIRKLLNTKKVGHTGTLDPEVIGILPIAIGSATRFIQYLPQGKTYIGQIKLGIRTNTDDIHGEIINQKSWPKISDEKLDQYLNRFRGIIKQIPPKVSSVHINGERAYKKSFRNEVFELAPREVKIDELTLMKWDQINGILEIKVKCSAGTYIRAIARDLGEILNSEGCLLQLKRISACGFDEQNSIKISDIEKDKKNSKNFIIPTISALNHISSFVLSTEEQINFWQTGRAIRVDINYFQENKSFDYKKPIKVIDKKQILLGIGFLNEEQSNINPKLVLNAK
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: SP1L4_ARATH
Sequence: MGKARGVNSGGGESSLGYLFGSGESVPKPNKPNAKTGFTTTTTTTTTTDGAGGRPKTTTTTTTTGDKNKTEENSAGVRGSPNNYYRSDGQNCGNFLTERPSTKVHAAPGGGSSLGYLFGSGPCGSDK
What is the function of this protein?
Acts redundantly with SPR1 in maintaining the cortical microtubules organization essential for anisotropic cell growth.
What are the official names of this protein?
Protein SPIRAL1-like 4.
What is the protein family that this protein belongs to?
Belongs to the SPIRAL1 family.
Protein: TRUB_COXBU
Sequence: MTATNHPKLFKRPVDGVLLLDKPGGMTSNEALQRVKRLFHAKKAGHTGSLDPLATGLLPICLGEATKFSQFLLEADKSYSVKGRLGVRTASGDSESPILTERPIPKLTKRALEKTLFAFRGVIDQTPSMYSALKHKGQPLYKLARQGIEVERKTRQVTIYELTLLDWDNESIELYVHCSKGTYIRTLLDDVGEALGCGAHVVALRRLRVAHYHEDQMIKLAHLEREYDKANYTGLDRYLLPLETMVSHFPAIKLSSSTAFYLQQGQAVMVPNAPTHGFVRLRDQNDQFIGIGEILSDARIAPRRLIQKR
What is the function of this protein?
Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase B, tRNA pseudouridine(55) synthase, Psi55 synthase, tRNA pseudouridylate synthase, tRNA-uridine isomerase.
What is the protein family that this protein belongs to?
Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
Protein: XYNC_ASPFU
Sequence: MVVLSKLVSSILFVSLVSAGVIEERQAASINQAFTSHGKKYFGTASDQALLQKSQNEAIVRKDFGQLTPENSMKWDATEPSQGRFNFAGADFLVNYAKQNGKKVRGHTLVWHSQLPSWVSAISDKNTLTSVLKNHITTVMTRYKGQIYAWDVVNEIFNEDGSLRDSVFSRVLGEDFVRIAFETARSVDPSAKLYINDYNLDSASYGKTQGMVRYVKKWLAAGIPIDGIGTQTHLGAGASSSVKGALTALASSGVSEVAITELDIAGASSQDYVNVVKACLDVPKCVGITVWGVSDRDSWRSGSSPLLFDSNYQPKAAYNAIIAAL
What is the function of this protein?
Endo-1,4-beta-xylanase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose.
What are the official names of this protein?
Endo-1,4-beta-xylanase C, Xylanase C, 1,4-beta-D-xylan xylanohydrolase C.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 10 (cellulase F) family.
What are the subcellular locations of this protein?
Secreted.
Protein: FADB_BACSU
Sequence: MNAISLAVDQFVAVLTIHNPPANALSSRILEELSSCLDQCETDAGVRSIIIHGEGRFFSAGADIKEFTSLKGNEDSSLLAERGQQLMERIESFPKPIIAAIHGAALGGGLELAMACHIRIAAEDAKLGLPELNLGIIPGFAGTQRLPRYVGTAKALELIGSGEPISGKEALDLGLVSIGAKDEAEVIEKAKALAAKFAEKSPQTLASLLELLYSNKVYSYEGSLKLEAKRFGEAFESEDAKEGIQAFLEKRKPQFKGE
What is the function of this protein?
Involved in the degradation of long-chain fatty acids.
What are the official names of this protein?
Probable enoyl-CoA hydratase.
What is the protein family that this protein belongs to?
Belongs to the enoyl-CoA hydratase/isomerase family.
Protein: CLE26_ARATH
Sequence: MRNNHSLRLQLWFRTLFTVGVVTLLMIDAFVLQNNKEDDKTKEITTAVNMNNSDAKEIQQELEDGSRNDDLSYVASKRKVPRGPDPIHNRFLLLSRFILSLLTNPYPYLHICVLDVSV
What is the function of this protein?
Extracellular signal peptide that regulates cell fate.  Represses root apical meristem maintenance.  Regulates the transition of protophloem cells from proliferation to differentiation, thus impinging on postembryonic growth capacity of the root meristem; this signaling pathway requires CRN and CLV2 (PubMed:28607033).
What are the official names of this protein?
CLAVATA3/ESR (CLE)-related protein 26.
What is the protein family that this protein belongs to?
Belongs to the CLV3/ESR signal peptide family.
What are the subcellular locations of this protein?
[CLE26p]: Secreted, extracellular space.
Protein: FLGH_RHOPT
Sequence: MSKSVPLQRIVLVAALMATGGLAGGCSSIDRLAAIGERPALTPIENPTTQPGYKPVQMPMPKPEVASYNANSLWRNGSRAFFKDQRAAKVGDILTVTVNFTDKANIANETQRSRTSKEDSGITDFIGSKTITTPATAVLPGRILTTDSTSSSDGKGSVQRQEALQTNVAAVVTQVLPNGNLVVEGKQEIRVNFEIRELIVAGIVRPEDIQSDNTIDSSKIAQARIAYGGRGQITDVQQPRYGQQVMDVLLPF
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.
Protein: DNJ6A_XENLA
Sequence: MVEYYEVLGVQRNASADDIKKAYRRLALKWHPDKNPDNKDEAERRFKEVAEAYEVLSDSKKRDIYDKYGKEGLTNRGGGSHFDEAPFQFGFTFRSPDDVFRDFFGGRDPFSFDLFADDPFDDFFGRSRHRANRSRPAGGGGGPFLSTFGGFPAFGPSFSPFDSGFSSSFGSFGGHGGHGGFTSFSSSSFGGSEMGNFRSVSTSTKVVNGRRVTTKRIVENGQERVEVEEDGQLKSLTVNGKEQLLRLDNK
What is the function of this protein?
Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70.  Plays an indispensable role in the organization of KRT8/KRT18 filaments.  Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin.  Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins.  Also reduces cellular toxicity and caspase-3 activity.
What are the official names of this protein?
DnaJ homolog subfamily B member 6-A.
What are the subcellular locations of this protein?
Cytoplasm, perinuclear region. Nucleus.
Protein: ATPE_ECO81
Sequence: MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.
What are the official names of this protein?
ATP synthase epsilon chain, ATP synthase F1 sector epsilon subunit, F-ATPase epsilon subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase epsilon chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: COXX_RICPU
Sequence: MSSLVRPINLGKINHSQSTVKDYILLMKPRVMSLVIFTGFVGMWLAPYSVHPFIAGIAVVCIALGAGSAGAINMWYDRDIDSLMKRTQKRPIVRGVIESDEALSFGLITGFFAVFFMALCVNLLASFLLLFTIFYYICIYTIWLKRRSIQNIVIGGVSGALPPVIGYAAVSNTISLESSILFLIIFIWTPPHSWALALFCNDDYKNCKVPMMPAVKGTLYTKKQILIYSILLFIVSLMPFFIGMNNFIYLIISGILGVVFLYYAGSLFYDTPDNKQAKRFFAYSIFYLFFIFLLLYSTNTISTIS
What is the function of this protein?
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
What are the official names of this protein?
Protoheme IX farnesyltransferase, Heme B farnesyltransferase, Heme O synthase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: FOLD_NEIM0
Sequence: MSAQLINGKEVSQKRLQAVAEAVAQRQQDNLHMPCLAVVLVGGDPASAVYVRNKKTACQKCGIKSLSYELPESTSQEELLALVDRLNADSEVDGILVQLPLPKHLDSQAVLERISPDKDVDGFHPYNVGRLAVKMPLMRPCTPKGVMTLLEAYGIDPKGKKAVVVGASNIVGRPQALELLLARATVTVCHSATENLADEVAGADILVVGVGIPNFVKGEWIKPGAVVIDVGINRLDDGSLCGDVEFETAKERAAMITPVPGGVGPMTIATLMENTLHAASLHDA
What is the function of this protein?
Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
What are the official names of this protein?
Bifunctional protein FolD.
What is the protein family that this protein belongs to?
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
Protein: DNAA_STAAE
Sequence: MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLSSIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPSTETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLIDDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIVDITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLLGKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPRQIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEIRNV
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ECFA1_BACC1
Sequence: MKKEKLRTENISFQYPGAATYALKDVSFSLYEGEWVSVIGQNGSGKSTLAKLLNGLFLPEAGTITVNDTMVLSEETVWDVRKQIGMVFQNPDNQFVGTTVQDDVVFGLENIGMPREQMVERLDQALRLVRMEDFLNDEPHSLSGGQKQRVAIAGVLALQPSILILDEATSMLDPQGRREVVETVRQLVNEKGITVLSITHDLEEAAQSDRVIILNKGEILEEGTPEQIFKSSHMLQEIGLDVPFSVKIAELLKRNEILLQNTHLTMESLVNELWRLHSKK
What is the function of this protein?
ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex.  Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
What are the official names of this protein?
Energy-coupling factor transporter ATP-binding protein EcfA1, ECF transporter A component EcfA1.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Energy-coupling factor EcfA family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.