PharMolix/UniProtQA huggingface dataset:
Protein: Y613_STRA3
Sequence: MLHKNDIIETEISDISHEGMGIAKVDGFVFFVENALPGEIIKMRVLKLRKRIGYGKVEEYLTTSPHRNEGLDYTYLRTGIADLGHLTYEQQLLFKQKQVADNLYKIAHISDVLVEPTLGMTIPLAYRNKAQVPVRRVDGQLETGFFRKNSHTLVSIEDYLIQEKEIDALINFTRDLLRKFDVKPYDEEQQSGLIRNLVVRRGHYTGQLMLVLVTTRPKIFRIDQMIEKLVSAFPSVVSIMQNINDRNSNVIFGKEFRTLYGSDTIEDQMLGNTYAISAQSFYQVNTEMAEKLYQKAIDFSDLNSEDIVIDAYSGIGTIGLSVAKQVKHVYGVEVVEKAVSDAKENATRNGITNSTYVADSAENAMAKWLKEGIKPTVIMVDPPRKGLTESFVYSAAQTKADKITYISCNSATMARDIKLFEELGYHLVKIQPVDLFPMTHHVECVALLVKA
What are the official names of this protein?
Uncharacterized RNA methyltransferase gbs0613.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
Protein: DNBI_HHV6Z
Sequence: MADENETVVSAPVSTAAWIYVFPKEKELLDVLSVLSLMERNSPVVISPLLMNLTVENDFSTTVKTPITNFGGTILTKITSFMPVCFFFHGTEQLVGMAEDHGDLIRLCEQTRQKFHLQSFEVPTARKVIDIKALCSAVGKDADSVICHVACGNGFKELLFAGLLIPCVEEQIQVQVGEYSCVKIPLYSATLFETEETISLSSCTEFIQERGFFLPALSETLFYYVFTSWGTTLRFSNTKELIDAGLKQFTQDGEQTVKLAPHKTYLGISGQKISAVEKDFLMLVDSVVTELSFSHVAEYLDSVYDPSQIMNFNDWPIIRNSETHAERMAQLTNLKLHLSSHLAVLIFAPNSILYCSKLAFIPNVKQAFNSVMTQELLLRSLSFCNALSSLTEDVYNDNRKIIKCDSTSGKDDKFSANHLAYACATCPQLLSYVVWNLNRMSVYNAGNAYTEIYNHLVNCSANLCEFCDGKCCQSCIGTAMVRVGTRLPAIPKNVKKEPLVMSMFSRYYAEVDILGSFGRKPVSELKEIGKDQQNTLSLDRGKFVSQIFDYCKKNSLIDPVTGEDTFNVRSKKDFVSIIHGLTQCIEECVSRCIVEMRRTQTPREQIENCLQSFNVDTTPYATAFSPFLTFAYYKVILTVLQNLALIVASGHVVDRPCTGNSISKWLVQQYQSLYGTFHSSYLKKGFLNTRTVKVASNVDMEQILDCDLYKSGKYVKTTIQAKLCRLSMQCLRDFRIKNRPFNKSSKTAHNNPYFKKNVKHKKNPLSGCISFLLFKYHDKLFPNVKISCLELWQRFLLNNVPKTLDIGNPEEVKTFIKFAFSITNTYDEIDIIDIQPECLSTFIDCYFHNKFLSALGFHDYLTSLHGLTSKLVTQNPVLFPVVLDKQPKFSSIQEYLVYVKKLVLDGVPNPVIASLSKEPNFGTIFTSRSLVTFGLTLEKFVSLANREYFQFGQLGWIGGSGVDRNLNPTSSALQDFRFMRQKTIIATKFSEVIVKKVRRETIMFDTEVVKGKVLSIVENLTNDIDPELLIIAEVMRDREDKPTMDDMLFFVDGREALAASIMLKLNHLVDMNVRDFSIANLQSVFEAVSSNDAPVYDFSEILAEEDDQASGVLKCDETETETDEPMTKKNRL
What is the function of this protein?
Plays several crucial roles in viral infection.  Participates in the opening of the viral DNA origin to initiate replication by interacting with the origin-binding protein.  May disrupt loops, hairpins and other secondary structures present on ssDNA to reduce and eliminate pausing of viral DNA polymerase at specific sites during elongation.  Promotes viral DNA recombination by performing strand-transfer, characterized by the ability to transfer a DNA strand from a linear duplex to a complementary single-stranded DNA circle.  Can also catalyze the renaturation of complementary single strands.  Additionally, reorganizes the host cell nucleus, leading to the formation of prereplicative sites and replication compartments.  This process is driven by the protein which can form double-helical filaments in the absence of DNA.
What are the official names of this protein?
Major DNA-binding protein.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae major DNA-binding protein family.
What are the subcellular locations of this protein?
Host nucleus. Note=In the absence of DNA replication, found in the nuclear framework- associated structures (prereplicative sites). As viral DNA replication proceeds, it migrates to globular intranuclear structures (replication compartments).
Protein: PRMA_NOSP7
Sequence: MANTWWELQILCEPDLEDSIFWRLEDFGCRGTASENKGNSSLVRAYLSTIQTQLLDLAALSLWLRQDALCVGVSSPSLQWQLIDEEDWATSWKQYWHPQEIGDRFLINPAWLPLPETTERLVIRLDPGVAFGTGNHATTQLCLESLEMRLSEVPQSFVGNSGKHKHLVIADIGCGSGILSIGALLLGAEKVYAVDNDPLAVQSTISNGLLNDISSERLLPALGSVDVLTKLLEKPVDGIVCNILAHVIIELIPEMSAIAKPETWAIFSGILLEQSKAVADALEQNGWVVATLWKRKEWCCLNVRRS
What is the function of this protein?
Methylates ribosomal protein L11.
What are the official names of this protein?
Ribosomal protein L11 methyltransferase, L11 Mtase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. PrmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EUTC_ECOSM
Sequence: MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCTTPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRIATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
What is the function of this protein?
Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds.  Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12.
What are the official names of this protein?
Ethanolamine ammonia-lyase small subunit, EAL small subunit.
What is the protein family that this protein belongs to?
Belongs to the EutC family.
What are the subcellular locations of this protein?
Bacterial microcompartment.
Protein: RL33_DECAR
Sequence: MAKGGREKIKLESTAGTGHFYTTSKNKRTTPEKLEFMKYDPKARKHVAYKEVKLK
What are the official names of this protein?
50S ribosomal protein L33.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL33 family.
Protein: PURA_LEPIC
Sequence: MPASLVVGTQWGDEGKAKVIDFLSKDTDIIVRYQGGANAGHTVVVHGKKYVFHLVPSGVIYDQTICVIGNGVVLDPLFFIEECDRLQKEGFPVFDKLLLSDACHLLFPYHSQIDSARETTLSQEHKIGTTKKGIGICYADKMMRTGLRVGDLLDTSYQTRLKHLVDEKNRELDKLYGMPPVSYNDINEGLKFFLSKVKKNIINTAYYLDTELKKGKRVLLEGAQGTGLDVDFGTYPYVTSSNPTTGGALIGTGIPFQHLKHVIGITKAYTTRVGEGPFPTELLGEAGEKLRQKGGEFGATTGRPRRCGWFDVEMLKHSVRINGITSIALTKIDILSDYDTIPVATGYKLNGKTLDCFPSQGLDKVEVIYEEFPGWKSDISGICEFQKLPEKCKNYISALEKWIGVKINLVSTGPDRKDTIHGDSF
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPOX_YEAST
Sequence: MLLPLTKLKPRAKVAVVGGGVSGLCFTYFLSKLRPDVEITLFESQNRTGGWIYSCNTRDMSGNPIMLEKGPRTLRGVSDGTVLIMDTLKDLGKEAVIQSIDKGCIADKKFLLDPSDKLVQVPNSISTTVKFLLNPLGKGLITGMMGEWFRKKSPHPGQDESVESICDRRFGNNYISNNMISALLRGIYGDDVSLLSAKRTFKKIYYNELKHGSNTQAMIDNMRGKSRSKKTENLHQSLTGCLNDYSNAFGKDRSKLLDLSNTLKKYPMLGLAGGLETFPKIVRNALNEFKNVKIVTGNPVTQIMKRPANETTIGLKAKSGDQYETFDHLRLTITPPKIAKLLPKDQNSLSKLLDEIQSNTIILVNYYLPNKDVIDADLQGFGYLVPKSNKNPGKLLGVIFDSVIERNFKPLFDKLSTNPNALNKYTKVTAMIGGCMLNEHGVPVVPSREVTINAVKDALNNHLGISNKDLEAGQWEFTIADRCLPRFHVGYDAWQERAERKLQESYGQTVSVGGMGFSRSPGVPDVIVDGFNDALQLSK
What is the function of this protein?
Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
What are the official names of this protein?
Protoporphyrinogen oxidase, PPO.
What is the protein family that this protein belongs to?
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Note=Bound to the mitochondrial inner membrane with its active site facing the cytosolic side.
Protein: YBEY_MYCPU
Sequence: MNIINITNKSNFRFMYKKEFLKIMDIIQEKFNFKKRISVDLLITDNKEVRENNLLYRNVDKETDVLSFPFGDPDFFDHLDFIPLGSIIISHEKIVAQALEFNHSKKREFCYLFTHSLLHLLGYDHKEEDEEKIMNQYTKEIVEKLNIYR
What is the function of this protein?
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
What are the official names of this protein?
Endoribonuclease YbeY.
What is the protein family that this protein belongs to?
Belongs to the endoribonuclease YbeY family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF84_ASFK5
Sequence: MPYSRDITKFITATEPEVGLPLLALQRSKSVIGIILLVISLLLIFIGIIILSVSSHTTAGSVLVVLSLILGGGGFFLIYKDNS
What are the official names of this protein?
Transmembrane protein EP84R, pEP84R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus EP84R family.
What are the subcellular locations of this protein?
Virion membrane.
Protein: RS14Z_STAHJ
Sequence: MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICFRELAYKGQIPGVRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14 type Z.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.
Protein: SYA_PROMM
Sequence: MAVARSLRSGDSRPRTGSEIRTAFLTFFAERAHQVIPSASLVPEDPTVLLTIAGMLPFKPVFMGQAERPAPRATSSQKCIRTNDIENVGRTARHHTFFEMLGNFSFGDYFKQQAIEWAWELTTEVFGLDPKNLVVSVFREDDEAETIWRDVVGVNPKRIMRMDEADNFWASGPTGPCGPCSEIYYDFKPDLGNDDIDLEDDGRFVEFYNLVFMQYNRDGEGNLTPLANRNIDTGMGLERMAQILQGVPNNYETDIIYPLIETAAGLAGLDYQKLDEKGKTSFKVIGDHCRAITHLICDGVTASNLGRGYIMRRLLRRVVRHGRLVGIEKPFLQAMGEAAIALMVEAYPQLEERRKLILAELNREEARFLETLERGEKVLADVLVANPQMISGGQAFELYDTYGFPLELTQEIAEEHGLTVDLQGFEQAMDQQRQRAKAAAVSIDLTLQGAIEQMAAELEATRFQGYEVLEQPCCVLALVVNGESAERASAGDSVQIVLDTTPFYGESGGQVGDHGVLSGEGSGGNGVIVTVDDVSRHRNVFVHFGRIERGTLALGDLVNAQVDRACRRRAQANHTATHLLQAALKQVVDSGIGQAGSLVDFDRLRFDFHCARAVTAKELEQIEALINGWIMESHDLIVEEMSIQEAKAAGAVAMFGEKYADVVRVVDVPGVSMELCGGTHVANTAEIGLFKIVAESSVAAGIRRIEAVAGPAVLAYLNERDEVVKKLLERLKVQPSEIVERVTSLQEELKSSQKALTAARAELAVAKSAALATQAVAVGEYQLLVARLDGVEGAGLQNAAQGLLDQLGDGAAVVLGGLPDPSDEGKVILVAAFGKQLIAQGQQAGKFIGSIAKRCGGGGGGRPNLAQAGGRDGAALDGALEAAKVDLQQALG
What is the function of this protein?
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala).  Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
What are the official names of this protein?
Alanine--tRNA ligase, Alanyl-tRNA synthetase, AlaRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y536_YERPB
Sequence: MNNPDDVLLINRFLRQQHVLTLCAGSGMDMWCASCFYVFDENQMALFLMTEKHTRHSELMLINPQVAGTVATQSRTIALIKGIQYRGDISLLSGDAEQAARNRYCRRFPVAKVSSAPLWQLNLLEIKMTNNALGFGKKLHWSRVEPL
What are the official names of this protein?
UPF0306 protein YPTS_0536.
What is the protein family that this protein belongs to?
Belongs to the UPF0306 family.
Protein: ARFP2_BOVIN
Sequence: MTDGILGKAATMEIPIHGNGEAGQLPEDDGLEQDLQQVMVSGPNLNETSIVSGGYGGSGDGLIPTGSGRHPSHSATPAGPGDEVARGIAGEKFDIVKKWGINTYKCTKQLLSERFGRGSRTVDLELELQIELLRETKRKYESVLQLGRALTAHLYSLLQTQHALGDAFADLSQKSPELQEEFGYNAETQKLLCKNGETLLGAVNFFVSSINTLVTKTMEDTLMTVKQYEAARLEYDAYRTDLEELSLGPRDAGTRGRLESAQATFQAHRDKYEKLRGDVAIKLKFLEENKIKVMHKQLLLFHNAVSAYFAGNQKQLEQTLQQFNIKLRPPGAEKPSWLEEQ
What is the function of this protein?
Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network.  May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2.  Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site.  Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria.  In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG.
What are the official names of this protein?
Arfaptin-2, ADP-ribosylation factor-interacting protein 2.
What are the subcellular locations of this protein?
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Protein: PYRH_STAA1
Sequence: MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAKMDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRVLTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVILMGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFSIMEEGNIKRAVMGEKIGTLITK
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_THEAB
Sequence: MEKHTLEALVRSVVGKKRAVRRLRRQGFVPGVVYGPDVEPLSISIKRSNLIKLFHEVTEASIISLTVKDENGKEVFSHDVFIKNVQYDKLTDEVKHVDFYAPEKGHKMKINLPLEFVGKAKGEEKGGVLEIHHHELPVETLPNAVVEKLEIDVSNLDLGQALYVKDLKLPEGMEAELDEEEIIAIVSTPSGLEVEEETGEEESAEPEVIEKGKKEEE
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: IL10H_EBVA8
Sequence: MERRLVVTLQCLVLLYLAPECGGTDQCDNFPQMLRDLRDAFSRVKTFFQTKDEVDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPEAKDHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQIKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTIKAR
What is the function of this protein?
Inhibits IFN-gamma synthesis.  Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules.  In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes (By similarity).
What are the official names of this protein?
Viral interleukin-10 homolog, vIL-10, 20 kDa protein, Protein BCRF1.
What is the protein family that this protein belongs to?
Belongs to the IL-10 family.
What are the subcellular locations of this protein?
Secreted.
Protein: PICAL_MOUSE
Sequence: MSGQSLTDRITAAQHSVTGSAVSKTVCKATTHEIMGPKKKHLDYLIQCTNEMNVNIPQLADSLFERTTNSSWVVVFKSLITTHHLMVYGNERFIQYLASRNTLFNLSNFLDKSGLQGYDMSTFIRRYSRYLNEKAVSYRQVAFDFTKVKRGADGVMRTMNTEKLLKTVPIIQNQMDALLDFNVNSNELTNGVINAAFMLLFKDAIRLFAAYNEGIINLLEKYFDMKKNQCKEGLDIYKKFLTRMTRISEFLKVAEQVGIDRGDIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRLKELAKKPHTSLTTAASPVSTSAGGIMTAPAIDIFSTPSSSNSTSKLPNDLLDLQQPTFHPSVHAMSAAPQGASTWGDPFSATLDAVEDAIPSLNPFLTKSSGDVHLPIASDVSTFTTRTPTHEMFVGFSPSPVAQPHSSAGLNVDFESVFGNKSTNVAVDSGGFDELGGLLKPTVASQNQSLPVAKLPPNKLVSDDLDSSLANLVGNLGIGNGTTKNDVSWSQPGEKKLTGGSNWQPKVAPTTAWSAATMNGMHFPQYAPPVMAYPATTPTGMIGYGIPPQMGSVPVMTQPTLIYSQPVMRPPNPFGPVSGAQIQFM
What is the function of this protein?
Cytoplasmic adapter protein that plays a critical role in clathrin-mediated endocytosis which is important in processes such as internalization of cell receptors, synaptic transmission or removal of apoptotic cells.  Recruits AP-2 and attaches clathrin triskelions to the cytoplasmic side of plasma membrane leading to clathrin-coated vesicles (CCVs) assembly.  Furthermore, regulates clathrin-coated vesicle size and maturation by directly sensing and driving membrane curvature.  In addition to binding to clathrin, mediates the endocytosis of small R-SNARES (Soluble NSF Attachment Protein REceptors) between plasma membranes and endosomes including VAMP2, VAMP3, VAMP4, VAMP7 or VAMP8.  In turn, PICALM-dependent SNARE endocytosis is required for the formation and maturation of autophagic precursors.  Modulates thereby autophagy and the turnover of autophagy substrates such as MAPT/TAU or amyloid precursor protein cleaved C-terminal fragment (APP-CTF).
What are the official names of this protein?
Phosphatidylinositol-binding clathrin assembly protein, Clathrin assembly lymphoid myeloid leukemia, CALM.
What is the protein family that this protein belongs to?
Belongs to the PICALM/SNAP91 family.
What are the subcellular locations of this protein?
Cell membrane. Membrane, clathrin-coated pit. Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle. Nucleus. Note=Colocalized with clathrin in the Golgi area. Interaction with PIMREG may target PICALM to the nucleus in some cells.
Protein: MAFK_CHICK
Sequence: MTTNPKPNKALKVKEESGENAPVLSDDELVSMSVRELNQHLRGLTKEEVIRLKQRRRTLKNRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMKLELDALRSKYEALQTFARTVARGPITPTKVATTSVITIVKSAEISSSSVPFSAAS
What is the function of this protein?
Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves.  However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites.  Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
What are the official names of this protein?
Transcription factor MafK.
What is the protein family that this protein belongs to?
Belongs to the bZIP family. Maf subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: KEFB_ERWT9
Sequence: MEGQSLLMAGLLYLCAAVIAVPLAARLGIGAVLGYLLAGIAIGPWGLGFISDVQEILHFSELGVVFLMFIIGLELKPSKLWELRRSIFGVGAAQVLLSAAVLGGLLWLTDFSWQAAIIGGIGLAMSSTAMALQLMRDKAMNRNESGQLGFSVLLFQDLAVIPALALVPLLAGSDSGHTDWMKLGMKVLAFAGMLVGGRYLLRPIFRFIAASGVREVFTAAALLLVLGSALFMEALGLSMALGTFIAGILLAESEYRHELEIAIDPFKGLLLGLFFISVGMALNLGVLYTHILEILAGVVMLVTVKTAVLYLLARIYGLRSSERLQFSGVLSQGGEFAFVLFSAASSTSLFSGDQMPLLLVTVTLSMMTTPLLMQGVDKILKHRFNEVDDSQEKPFVEDDKPQVIVVGFGRFGQVVARLLMANEKRITVLERDISAVSLMRSYGYKVYYGDATQLELLRAAGAETAQSLVIACNGPEDAMAIVHLCQQHFPHLQILARARGRVEAHELLQAGVTQFSRETFSSALELGRKTLMSLGMHPHQAFRAQQHFRRLDMRMLRALMPNHGDSQQISRVKEARRELEDIFQAELRHEKRQFDGWDEAD
What is the function of this protein?
Pore-forming subunit of a potassium efflux system that confers protection against electrophiles.  Catalyzes K(+)/H(+) antiport.
What are the official names of this protein?
Glutathione-regulated potassium-efflux system protein KefB, K(+)/H(+) antiporter.
What is the protein family that this protein belongs to?
Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. KefB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YHDY_BACSU
Sequence: MPDYLQQYFTLDNIIQIGISLAILLVFLILRKLFTRYFFNLLFNLTNRPKTEIFKQVVLAFDKPARWFFVALGLFLAIRYSPFLDEQMPVISKIYRSLIVALLCWGLCNLTATSSFIFHKVNQRFELDMDDILAPFLSKLLRFVIIALSVSVIAQEFNYDVNGFVAGLGLGGLAFALAAKDTISNFFGGIIIITEKPFTIGDWVETSTVTGSVEDITFRSTRFRTAQGALVTVPNSTLSMEAITNWTRMTKRQITFSIHVSYATPIENLERSIHSLRTMLLEHEGVDNEIIMVNFDTFADSYYNLFFNFYTKTTVWAENLNIREDINYKIIEILGAEGVQFAYPGQMVVVKQKHESDQFQVNLNKEEKERA
What is the function of this protein?
May play a role in resistance to osmotic downshock.
What are the official names of this protein?
Uncharacterized MscS family protein YhdY.
What is the protein family that this protein belongs to?
Belongs to the MscS (TC 1.A.23) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: A7056_ARTBC
Sequence: MRSTAYLTALLSFLGATHAAPEGPRCRCTPDQSCWPSPGLWQTLNKTLSGNLVAVKPVGTVCHDPTYNGGLCDSVKGMQTDSSWRSAQPGAVQSINWETWPEKNESCYIDGPRQVPCGQGRIPLYSAVVQSPLDIQKTVRFASKYNLRLVIKNTGHDFLGRSTGPQSLQILTHNMKSINFTDNFVPEGKPDGRGIGQAVTIGAGVQLNELYEAAGKRGLTQVIGLSTTVGAAGGYIQGGGHSPLGPWKGMSTDHVLEYKVVTAGAKFVTANEYQNSDLFWALRGGGGGTFGVVTSVTLRTFKDPPTIVSQVNVTMDGKANESYWAAVEKFQAYLPTLSDGGCSGYYYMLPNVTLGPQSAAVIIAAFYYANKTDKAHVDNLYRPLFASLSSIPGINVASVSVPVSSSTEAFRSAFDQKPPRDGGGVNILGSRLFSRKLLEAPGGAANLTAALSKLDFKNLQPAIGHLVAGGQVAKNTHIQSALNPSWRKALVHLVISRDWSIDSTFAEQEKISTKLTAEEIPLLAAVEPDMGAYTNEADVNEPRFQQTFWGTNYNTLLRVKNRWDPRGLFFVRSGVGSEAWDKQGLCRA
What are the official names of this protein?
Uncharacterized FAD-linked oxidoreductase ARB_02478.
What is the protein family that this protein belongs to?
Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
Protein: FMT_ANAPZ
Sequence: MKVVFMGSSEFSLPAFEALVSADSYDVVAVYTKAPKPAGRGYALTKTPVHICAEGKGIPVRSPVSLRAEGEESIMAEYAPDVIVVVSYGLMLPKWTLTASRMGCVNIHPSLLPRWRGAAPMQHAILSGDTVTGVTIMQINEFMDAGDIYLQEVTEIGEKENILDLSRRLSVMGSRMLLKVLDSIGSIQPIKQDESGVTIANKLEEFRIDFEEAADVICRRIRALYPKMYFMLDGSRVRVLEAESYEFAEMNIGDVINNELHIRCGGNTALVPLVVQQESKKPCDIKSFLCRFRGKSMPVVS
What is the function of this protein?
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet).  The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
What are the official names of this protein?
Methionyl-tRNA formyltransferase.
What is the protein family that this protein belongs to?
Belongs to the Fmt family.
Protein: RMA1_ARATH
Sequence: MALDQSFEDAALLGELYGEGAFCFKSKKPEPITVSVPSDDTDDSNFDCNICLDSVQEPVVTLCGHLFCWPCIHKWLDVQSFSTSDEYQRHRQCPVCKSKVSHSTLVPLYGRGRCTTQEEGKNSVPKRPVGPVYRLEMPNSPYASTDLRLSQRVHFNSPQEGYYPVSGVMSSNSLSYSAVLDPVMVMVGEMVATRLFGTRVMDRFAYPDTYNLAGTSGPRMRRRIMQADKSLGRIFFFFMCCVVLCLLLF
What is the function of this protein?
E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of aquaporin PIP2-1.  Forms a ubiquitin ligase complex in cooperation with the E2 enzymes UCB8/UCB10.
What are the official names of this protein?
E3 ubiquitin-protein ligase RMA1, Protein RING membrane-anchor 1, RING-type E3 ubiquitin transferase RMA1.
Protein: MYC_MOUSE
Sequence: MDFLWALETPQTATTMPLNVNFTNRNYDLDYDSVQPYFICDEEENFYHQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVATSFSPREDDDGGGGNFSTADQLEMMTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSTSLSPARGHSVCSTSSLYLQDLTAAASECIDPSVVFPYPLNDSSSPKSCTSSDSTAFSPSSDSLLSSESSPRASPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQTPAKRSESGSSPSRGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRAKLDSGRVLKQISNNRKCSSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSIQADEHKLTSEKDLLRKRREQLKHKLEQLRNSGA
What is the function of this protein?
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'.  Activates the transcription of growth-related genes.  Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis.  Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells.  Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (PubMed:31005419).  Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
What are the official names of this protein?
Myc proto-oncogene protein, Proto-oncogene c-Myc, Transcription factor p64.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: Y4229_AERS4
Sequence: MSIKEWPEDERPREKLLRQGPATLSDAELLAIFLRTGVNGLSAVDLSRQLLQQFGSLRALLGADQGAFCHAHGLGPAKYAQLQAVLEMGKRHLAEQLQRGDALTSPQLTRDYLQAQLREVFALLLLDNQHRVIQFVELFYGTLDSASVWPREIVQIALKHNAAAVILAHNHPSGVAEPSRADRQITDRILAALALIDIRVLDHLVIGDGITVSFAERGWL
What are the official names of this protein?
UPF0758 protein ASA_4229.
What is the protein family that this protein belongs to?
Belongs to the UPF0758 family.
Protein: DESAT_BOMMO
Sequence: MPPNSVDKTNETEYLKDNHVDYEKLIAPQASPIKHKIVVMNVIRFSYLHIAGLYGLYLCFTSAKLATSVFAIVLFFLGNFGITAGAHRLWSHNGYKVKLPLEILLMVFNSIAFQNTIFTWVRDHRLHHKYTDTDADPHNATRGFFFSHIGWLLVRKHPMVKIAGKSLDMSDIYCNPLLRFQKKYAIPFIGTICFIIPTLAPMYFWGESLNNAWHITVLRYIFSLNGTFLVNSAAHLWGYKPYDKSLKATQSGMANAFTFGEGFHNYHHVFPWDYRADELGDRYINLTTRFIDFFAWMGWAYDLKTASTNIIEKRALRTGDGTYKRPNGMN
What is the function of this protein?
Fatty acid desaturase that catalyzes 2 consecutive steps in the biosynthesis of bombykol, a sex pheromone produced by the moth.  First acts as an acyl-CoA Delta(11) desaturase (1) by catalyzing the formation of Delta(11) fatty acyl precursors.  Then acts as a (11Z)-hexadec-11-enoyl-CoA conjugase (2) by converting a single cis double bond at position 11 of (11Z)-hexadec-11-enoyl-CoA into conjugated 10 trans and 12 cis double bonds.
What are the official names of this protein?
(11Z)-hexadec-11-enoyl-CoA conjugase, Bmpgdesat1, Acyl-CoA Delta(11) desaturase, Acyl-CoA Z11/delta10,12 desaturase.
What is the protein family that this protein belongs to?
Belongs to the fatty acid desaturase type 1 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.