PharMolix/UniProtQA huggingface dataset:
Protein: CYH1_MOUSE
Sequence: MEDDDSYVPSDLTAEERQELENIRRRKQELLADIQRLKEEIAEVANEIESLGSTEERKNMQRNKQVAMGRKKFNMDPKKGIQFLIENGLLKNTCEDIAQFLYKGEGLNKTAIGDYLGERDEFSIQVLHAFVELHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCQCNTGVFQSTDTCYVLSFAIIMLNTSLHNPNVKDKPTVERFIAMNRGINDGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDSKKPNCFELYIPDNKDQVIKACKTEADGRVVEGNHTVYRISAPTPEEKEDWIKCIKAAISRDPFYEMLAARKKKVSSTKRH
What is the function of this protein?
Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6 (PubMed:18042453, PubMed:20080746).  Promotes the activation of ARF factors through replacement of GDP with GTP (PubMed:18042453).  Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity (PubMed:20080746, PubMed:29420262).
What are the official names of this protein?
Cytohesin-1, PH, SEC7 and coiled-coil domain-containing protein 1, CLM1, SEC7 homolog A, mSec7-1.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein. Cytoplasm, cytosol. Cell junction, tight junction. Cell junction, adherens junction. Note=Colocalized with TJP1 during epithelial polarization (PubMed:20080746).
Protein: CLPX_LACJO
Sequence: MANEITEQEEVKCSFCGKPQSQVKKIVAGNGVYICNECIDLSKKIIDDELKADSIKETKDLPKPMEIKKQLDEYVIGQDRAKKVLSVAVYNHYKRISQMDIDSTGTELQKSNIALIGPTGSGKTYLAQTLAKILNVPFAIADATTLTEAGYVGEDVENILLKLLQNADYDIERAQRGIIYIDEIDKISKKAENVSITRDVSGEGVQQSLLKILEGTIASVPPQGGRKHPQQQMIKIDTTNILFIVGGAFDGIENIVKNRLGKKTIGFGAENGLNQVDADDWQKNLTTGDLVKFGLIPEFIGRIPIIATLDKLSTEDLIRILTEPKNALVKQYKKLLSLDDVDLEFTDGALQAIADMAISRRMGARGLRSIVENSLMDVMYRTPSDDNIKEVQITKDVITKHAEPKITYKEDKAEKTSEATK
What is the function of this protein?
ATP-dependent specificity component of the Clp protease.  It directs the protease to specific substrates.  Can perform chaperone functions in the absence of ClpP.
What are the official names of this protein?
ATP-dependent Clp protease ATP-binding subunit ClpX.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family.
Protein: RS8_METCA
Sequence: MSMSDPLSDLLTRIRNGQAAGKAEIIVPASKLKRAVCQVLKEEGYIAGFSDVTEQGKHNIRVELKYHNGAPVIDKIQRVSKPGCRRYRGRDELPKVMGGFGIAIVSTSKGVMSDRRARSVGEGGEVLCVVE
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S8.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS8 family.
Protein: GCST_BORPA
Sequence: MSAPLKRTPLAEEHLAAGARMVDFGGWDMPLAYGSQLEEHHAVRQDAGMFDVSHMLNVDVGGADATAFLRRLVANDVARLATPGRALYSCMLNPQGGIIDDLIIYYFAPDQWRVVVNAGTADKDIAWMQRVAAADGFDVAIAPRRDLAMVAVQGPNARAKVWAARPAWQAASEPLAPFSAAAVEAGTLVARTGYTGEDGFEIVLPADAVVQLWRDLLAQGVRPCGLGARDTLRLEAGMNLYGQDMDELVHPDQAGLSWTVALKDEARRFVGRDAIEQFAVPRAFVGLKLQERGVMRAHMPVRCAQGMGELTSGTMSPTLGVSVGFARVPVGVQPGDAVEVEIRGKWVPALVCKLPFVRHGKAVEHS
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: COAD_NOCSJ
Sequence: MTRAVCPGSFDPVTNGHLDIVRRAAAIFDELVVATGTNVSKSRLFDPEERLEMLREVCADLPNVTVMGFTGLIVDFCRDIDAQAIVKGLRGGNDYEYELPMAQMNAHLTGVETVFLTTHASWGYVSSSLVKEVASLGGDVSALVPPAVHGRLQARLAAG
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: QUEC_YERPG
Sequence: MKRAVVVFSGGQDSTTCLIQALQQYDEVHCITFDYGQRHRTEIDVARELALQLGATAHKVLDVGMLNELAVSSLTRDSIPVPSYDANADGALPSTFVPGRNILFLTLASIYAYQVQAQAVITGVCETDFSGYPDCRDEFIKALNHAIDLGIGRDIAFITPLMWLDKAETWALADYYQQLDLIRHHTLTCYNGIKGDGCGQCAACHLRAKGLASYMANKQQVILNLKQKVGLA
What is the function of this protein?
Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
What are the official names of this protein?
7-cyano-7-deazaguanine synthase, 7-cyano-7-carbaguanine synthase, PreQ(0) synthase, Queuosine biosynthesis protein QueC.
What is the protein family that this protein belongs to?
Belongs to the QueC family.
Protein: RGI2_YEAS8
Sequence: MTKKDKKAKGPKMSTITTKSGESLKVFEDLHDFETYLKGETEDQEFDHVHCQLKYYPPFVLHDAHDDPEKIKETANSHSKKFVRHLHQHVEKHLLKDIKTAINKPELKFHDKKKQESFDRIVWNYGEETELNAKKFKVSVEVVCKHDGAMVDVDYRTEPLQPLI
What is the function of this protein?
Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.
What are the official names of this protein?
Respiratory growth induced protein 2.
What is the protein family that this protein belongs to?
Belongs to the RGI1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRPA_SHIB3
Sequence: MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATSS
What is the function of this protein?
The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.
What are the official names of this protein?
Tryptophan synthase alpha chain.
What is the protein family that this protein belongs to?
Belongs to the TrpA family.
Protein: MTFA_PECAS
Sequence: MIKWPWNNSQPQVQTLEHWQAAISIPLLAPLSDEEHQKLAALADQFLKQKRLIPLQELLLTDIMQRRIALLFSLPVLSLGIGALDGFHEVLVYPGPFIVEEEWQDDIGLVHTGKMVQSGQSWDQGPIVLNWQEVQDSFDLSGFNLIIHEVAHKLDIRSSGEATGVPLIPLRDIAVWEQHLHSAMDALQEEIDLVGEDAASMDPYAVHDPAECFAVLSEYFFSAPELLEERFPDLYRCFQKFYRQDPLARLKSWQNNINYRAPSIY
What is the function of this protein?
Involved in the regulation of ptsG expression by binding and inactivating Mlc.
What are the official names of this protein?
Protein MtfA, Mlc titration factor A.
What is the protein family that this protein belongs to?
Belongs to the MtfA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RABH_DICDI
Sequence: MIKDNIKLKLTIIGDWNVGKSSLLYRFFNDVFYEQTKLSMGEHFFYKTVLIRGESIDLQITDTSGMEKFRSLNNSFYSNLDGILIVYDISDQETFENTKLWLNEANKLAPKDCIKIIVASKFDLENKVVDSNIVKSYADNLNLKFFETSSKNSINVEETFITLVEDILLKKNYQFNNITKNKNNQDEDFNKKKGCSIN
What are the official names of this protein?
Ras-related protein RabH.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Rab family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor; Cytoplasmic side.
Protein: YBAB_ECOLC
Sequence: MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLPPGFKMPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein YbaB.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: ATPB2_DINSH
Sequence: MANAKGKVTQVIGAVVDVQFEDTLPEILNALNTENNGKKLVLEVAQHLGENTVRTIAMDATEGLVRGAEVTDTGGPITIPVGNATLGRIMNVIGEPIDEKGPVEASESRAIHQPAPEFSEQSTGSEILVTGIKVIDLLAPYSKGGKIGLFGGAGVGKTVLIMELINNIAKVHSGYSVFAGVGERTREGNDLYHEMIESNVIKPDNLSESQVALVYGQMNEPPGARARVALTGLTLAEQFRDQSGTDVLFFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATDMGQMQERITSTKGGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRAISELGIYPAVDPLDSSSRILDPGIVGEEHYQVARDVQGILQRYKSLQDIIAILGMDELSEEDKLTVARARKIQRFLSQPFDVAKVFTGSDGVQVPIEDTISSFKAVVAGEYDHLPEGAFYMVGGIDEVIAKAERMAADAA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta 2, ATP synthase F1 sector subunit beta 2, F-ATPase subunit beta 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: SUS4_ORYSJ
Sequence: MSGPKLDRTPSIRDRVEDTLHAHRNELVALLSKYVSQGKGILQPHHILDALDEVQSSGGRALVEGPFLDVLRSAQEAIVLPPFVAIAVRPRPGVWEYVRVNVHELSVEQLTVSEYLRFKEELVDGQYNDPYILELDFEPFNASVPRPNRSSSIGNGVQFLNRHLSSIMFRNKDCLEPLLDFLRGHRHKGHVMMLNDRIQSLGRLQSVLTKAEEHLSKLPADTPYSQFAYKFQEWGLEKGWGDTAGYVLEMIHLLLDVLQAPDPSTLETFLGRIPMIFNVVVVSPHGYFGQANVLGLPDTGGQIVYILDQVRALENEMVLRLKKQGLDFTPKILIVTRLIPEAKGTSCNQRLERISGTQHTYILRVPFRNENGILRKWISRFDVWPYLEKFAEDAAGEIAAELQGTPDFIIGNYSDGNLVASLLSYKMGITQCNIAHALEKTKYPDSDIYWTKYDEKYHFSCQFTADIIAMNNADFIITSTYQEIAGSKNTVGQYESHTAFTLPGLYRIVHGIDVFDPKFNIVSPGADMSIYFPYTEKAKRLTSLHGSLENLISDPEQNDEHIGHLDDRSKPILFSMARLDRVKNITGLVEAYAKNARLRELVNLVVVAGYNDVKKSKDREEIAEIEKMHELIKTYNLFGQFRWISAQTNRARNGELYRYIADTHGAFVQPAFYEAFGLTVVEAMTCGLPTFATVHGGPAEIIEHGISGFHIDPYHPDQAANLIADFFEQCKQDPNHWVEVSNRGLQRIYEKYTWKIYSERLMTLAGVYGFWKYVSKLERRETRRYLEMFYILKFRELAKTVPLAVDEAH
What is the function of this protein?
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways.
What are the official names of this protein?
Sucrose synthase 4, OsSUS4, Sucrose-UDP glucosyltransferase 4.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 1 family. Plant sucrose synthase subfamily.
Protein: NRFA_DESPS
Sequence: MNKSYKILLTGSVIAIGAMGLMANSINSREAERKEINTGPVVQAEGVASKNEEWYRYYPREYDSWKQTKKSDKITDLLREKPQLAIIWAGYGFAKDYNAPRGHFYAIQDNINTLRTGAPTGPSNGPMPTACWTCKSPDVPRLMDEVGENEFFTGKWAKYGNQIVNPIGCADCHNSQTGNLGFSRPHLGRALEASGVNLDEITFQDMRTLVCAQCHVEYYFRPTEWTDKTGKTKTAKVVTLPWAKGLSAENMEEYYDEYSFKDWTHKISKAPMLKAQHPGYELFSKGIHAQNGVSCADCHMPYKQQGSIKYTDHNIGNPLDDIASTCLTCHRDSEKAFRDRVASKLERKEQLMKMAMDTLAAAHLEAGKAWELGATEAEMQPVLELLRSGQWLWDYSIASHGSFFHSPEETLRLLGVANDKGGKARIKLAAILAQHGLIGYQVPDFSTKEKAQALAGVPLQKLITEKKAFESTLLEQWNEEAVKAGRLDPKTLEGMSNKSSWSQTELSQ
What is the function of this protein?
Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process.
What are the official names of this protein?
Cytochrome c-552, Ammonia-forming cytochrome c nitrite reductase, Cytochrome c nitrite reductase.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c-552 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: RL36_STRTD
Sequence: MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: ATPB_LEPBA
Sequence: MNKGKIKQIIGSVMDISFESGNMPEIYNAVEIQTKVNGKDVTITAEVQQHIGDNTVRAISLQSTDGLKRGLEVTDTGIPISVPVGTKTLGRIFNVLGEAIDELGDLPKDVKKMPIHRNAPTYEEIKPKTEIFETGIKVIDLLAPYIKGGKTGLFGGAGVGKTVLIQELINNIAKQHGGFSVFAGVGERTREGNDLWNEMKESGVIDKTVLCFGQMNEPPGARLRVALSALTMAENFRDESGSDILLFVDNIFRFSQAGSEVSALLGRMPSAVGYQPTLSTEMGGLQERITSTTRGSITSVQAIYVPADDLTDPAPATAFTHLDATTVLSRAISEKGIYPAVDPLDSTSRIMNPQIVGEEHYSTAREVQRILQRYKDLQDIIAILGMDELSEDDKILVARARRLEKFLSQPFHVAEQFTGRPGKYVKLEDTIRSFKGIIEGKYDSLPEQAFYMVGSIDEVIEAAKQLKG
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: PSAB_EUCGG
Sequence: MALRFPRFSQGLAQDPTTRRIWFGIATAHDFESHDDITEERLYQNIFASHFGQLAIIFLWTSGNLFHVAWQGNFEAWVQDPLHVRPIAHAIWDPHFGQPAVEAFTRGGALGPVNIAYSGVYQWWYTIGLRTNEDLYTGALFLLFLSAISLIAGWLHLQPKWKPSVSWFKNAESRLNHHLSGLFGVSSLAWTGHLVHVAIPGSRGEYVRWNNFLDVLPHPEGLGPLFTGQWNLYAQNPDSNSHLFGTSQGSGTAILTLLGGFHPQTQSLWLTDIAHHHLAIAFIFLVAGHMYRTNFGIGHSIKDLLEAHTPPGGRLGRGHKGLYDTINNSIHFQLGLALASLGVITSLVAQHMYSLPAYAFIAQDFTTQAALYTHHQYIAGFIMTGAFAHGAIFFIRDYNPEQNEDNVLARMLDHKEAIISHLSWASLFLGFHTLGLYVHNDVMLAFGTPEKQILIEPIFAQWIQSAHGKTSYGFDVLLSSTNSPAFNAGQSIWLPGWLNAINENSNSLFLTIGPGDFLVHHAIALGLHTTTLILVKGALDARGSKLMPDKKDFGYSFPCDGPGRGGTCDISAWDAFYLAVFWMLNTIGWVTFYWHWKHITLWQGNVSQFNESSTYLMGWLRDYLWVNSSQLINGYNPFGMNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLAWAHERTPLANLIRWRDKPVALSIVQARLVGLAHFSVGYIFTYAAFLIASTSGKFG
What is the function of this protein?
PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX.  PSI is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn.  Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin.
What are the official names of this protein?
Photosystem I P700 chlorophyll a apoprotein A2, PSI-B, PsaB.
What is the protein family that this protein belongs to?
Belongs to the PsaA/PsaB family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi- pass membrane protein.
Protein: CYB_PHYBS
Sequence: MTNIRKSHPLIKIINHSFIDLPTPSNISAWWNFGSLLGMCLALQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYTHANGASMFFIFLYFHIGRGIYYGSYTYTETWNIGVILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFVLPFIVTAMVMIHLLFLHETGSNNPSGVNSDSDKIPFHPYYTIKDILGLLFMFITLTMLILFSPDLLVDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVIALVFSILILVLLPIIHTSKQRSMSFRPFSQYLLWILVANLMILTWIGSQPVEYPFITIGQLASISYFCIILIIMPATSYMENKMLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: SPB5_XENTR
Sequence: MDALRLANTALAVDIFKKLCEKSATDNFVCSPLCISSSLSLIRKGSQGNTASELEKALHFEKVKDPDFGFQLLSSDISKISSANSLKLLKRVYVDNSIECKKDFINSAKKPYPLELETIDFKSQAEEARTQINSSVKELTDGNFETVLNEGSCDENTKIIMLGAASFKGKWVYTFNKSETKEMDFHINKKETKPVQMMHLEARLSIGYINELKTMVLEMPFQSKHFSMLILLPKDIEDDSTGLKKLEQDMTFEKYTHWTNPSMMANSKVKVSLPKFKMENSYDLKDMLKSLGINDAFNEEASDFSEMTESKGISISQAIQKACIEVDEDGTESADVSMERRLMNKEEFLADHPFIYILRHNKTRTIIMLGRYCGPSEAS
What is the function of this protein?
May not exhibit serine protease inhibitory activity.
What are the official names of this protein?
Serpin B5.
What is the protein family that this protein belongs to?
Belongs to the serpin family. Ov-serpin subfamily.
What are the subcellular locations of this protein?
Secreted, extracellular space.
Protein: SYM_HAEDU
Sequence: MSNKRKMLVTCALPYANGAIHLGHMLEHIQADIWVRFQRMRGHQVYFVCADDAHGTPIMLNAAKQGITPEQLIAKAKADHIADFQSFNISFDNYHSTHSEENRNITTAMYKTLRDKGLIKTRVISQLFDPEKQMFLPDRFVKGTCPKCQAEDQYGDNCEVCASTYSPMDLINPHSVVSGATPIVKQSEHFFFDLPNFEAMLKTWTHSGSLQPQIANKMQEWFESGLQQWDISRDAPYFGFPIPDTENKFFYVWLDAPIGYMASFKNLCDRTGLNYEEFWQKESKTELYHFIGKDIVYFHSLFWPAMLEGCDQRKPTNIFAHGYVTVDGVKMSKSRGTFIQASTYLKHIDPECLRYYYAAKLNERIEDLDLNLDDFVQRVNSDIVNKLVNLASRNASFITKRFAGNLADKLEDEALFAEFVAQASNIADHYEAREYNKAIRLIMDLCDKANKYVDDKAPWVIAKQADREAELHAVCSMGIELFRILISYLKPVLPQLATRAEAFLQTELRWDNIASPLLNQNVAPFKSLFSRLEKKQIDRVIEETKALFSTQPKTEQPQVASTMNDNQQQNIEPIAAEISIDDFAKLDLRVAKVIQCEAVPESNKLLKFQLDLGDHQRQVLSGIKAAYSKPEELNGRFVIMVANLAPRKMKFGLSEGMILSAGTGGADLFLLSGDCGIRPGMQVK
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y665_METMP
Sequence: MKSRKFFSKLKEESYDVSIFDLMNAKVYLEKDMTYLPQDYKKGYIEDFFTFFPEVLKEIKNKTEEEIEDFEIEDEEIKRVELRLCSMGSKQTGRESYEKLVKTVINYLIFINERPLHALTTRFPGGKQIIEKNGNYYCPIKNAQSNELSICEFCICKDLNEL
What are the official names of this protein?
UPF0305 protein MMP0665.
What is the protein family that this protein belongs to?
Belongs to the UPF0305 family.
Protein: DNJC2_BOVIN
Sequence: MLLLPSAADGQGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKAYEMLSDPVKRRAFNSVDPTFDNSVPSKSEAKDNFFEVFSPVFERNSRWSNKKNVPKLGDMNSSFEDVDAFYSFWYNFDSWREFSYLDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKADAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNLCKTWNHFSDSEAERVKMMEEVEKLCDRLELSSLQCLNETLTSSTKEVGKAALEKQIEEINEQIRKEKEEAEARMRQASKNAEKSAGGGGNGSKHWSEDDLQLLIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKSLQKLDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEGPCTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAAQEQVLNASRGKK
What is the function of this protein?
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus.  When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state.  In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain.  When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
What are the official names of this protein?
DnaJ homolog subfamily C member 2, Zuotin-related factor 1.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm, cytosol.
Protein: CLD19_RAT
Sequence: MANSGLQLLGYFLALGGWVGIIASTALPQWKQSSYAGDAIITAVGLYEGLWMSCASQSTGQVQCKLYDSLLALDGHIQSARALMVVAVLLGFVAMVLSVVGMKCTRVGDSNPTAKGRVAISGGALFLLAGLCTLTAVSWYATLVTQEFFNPSTPVNARYEFGPALFVGWASAGLAILGGSFLCCTCPEPERANSIPQPYRSGPSTAAREPVVKLSTSVKGPLGV
What is the function of this protein?
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
What are the official names of this protein?
Claudin-19.
What is the protein family that this protein belongs to?
Belongs to the claudin family.
What are the subcellular locations of this protein?
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Protein: ASP2_FRUSA
Sequence: XKEYND
What are the official names of this protein?
Acid shock protein 2.
Protein: RS17_METAC
Sequence: MARDIGLNIPAPSEECDDAYCPFHGTLPVRGQILVGTVVSSKMDNTVVIERQYMKMVSKYQRYEKRRSKIHAHNPACISAKVGDIVTIAECRPISKTKSYVVVKAEVPK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: RS11_LIMRD
Sequence: MATKKGTRKRRAKKNVETGVAHIHSTFNNTLIMITDVQGNAVAWSSAGVLGFKGSRKSTPFAAQMASEAAAKQAMEHGMKTVEVEVKGPGSGREAAIRALQATGLEVTAIRDVTPVPHNGSRPPKRRRV
What is the function of this protein?
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA.  Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
What are the official names of this protein?
30S ribosomal protein S11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS11 family.
Protein: SAHH_PSEPG
Sequence: MSAANMPAGFTDYKVADISLAAWGRRETIIAESEMPALMGLRRKYLTEQPLKGAKILGCIHMTIQTAVLIETLVALGAEVRWSSCNIFSTQDQAAASIAAAGIPVFAWKGETEEEYEWCLEQTILKDGQPWDANMILDDGGDLTELLHKKYPQVLDRVHGVTEETTTGVHRLLDMLAKGELKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSAQSLRQEGMIVKVTEVDPICAMQACMDGFELVSPFIDGINDGTEASIDKALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGAGSFDPQNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIFLFEQKYADLSAEKKAERLTVEVLPKKLDEEVALEMVRGFGGVVTKLTKQQADYIGVTVEGPFKPHAYRY
What is the function of this protein?
May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
What are the official names of this protein?
Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase, AdoHcyase.
What is the protein family that this protein belongs to?
Belongs to the adenosylhomocysteinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: O36O_CONAE
Sequence: MSRLGIMVLTLLLLVFIVTSHQDAGEKQATHRGAINFRWRRSLIRRTATEECEEYCEDEEKTCCGLEDGEPVCATTCLG
What are the official names of this protein?
Conotoxin ArMSGL-021.
What is the protein family that this protein belongs to?
Belongs to the conotoxin O3 superfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: KGUA_CERS4
Sequence: MARRGLLLILSSPSGAGKSTLSKRLTAWDPSIRFSVSATTRAPRPGEVDGRDYYFRTRDEFIAAVEAGEMLEHAEVFGNFYGSPKAPVEKALEQGHDTLFDIDWQGGQQIRNSSLGRDVVSIFVLPPSIGELDRRLRSRAQDSEEVIATRMARSKDEISHWAEYDYVLVNRDLDLAEEQLKMILSAERLRRDRQPDLMDFVRGLNGEFETR
What is the function of this protein?
Essential for recycling GMP and indirectly, cGMP.
What are the official names of this protein?
Guanylate kinase, GMP kinase.
What is the protein family that this protein belongs to?
Belongs to the guanylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PYRH_PSEPF
Sequence: MAQQGSGYQARYKRILLKLSGEALMGSEEFGIDPKVLDRMALEVGQLVGIGVQVGLVIGGGNLFRGEALSKAGMDRVTGDHMGMLATVMNALAMRDALERANISAIVMSAISMVGVTDHYDRRKAMRHLNSKDVVIFAAGTGNPFFTTDSAACLRAIEIDADVVLKATKVDGVYTADPFKDPHAEKFDHLTYDEVLDRKLGVMDLTAICLCRDHKMPLRVFNMNKPGALLNIVHGGAEGTLIEEVQQ
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPX3_PARTE
Sequence: MSQSDLDRQIAQLRNCENITEGEVKALCTKAREILVEESNVQRVDAPVTICGDIHGQFFDLMELFKVGGDCPDTNYLFLGDFVDRGFNSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSLNVWRYCTDIFDYLSLAAVIEEKIFCVHGGLSPSIKTMDDIRAIDRKQEVPHDGAMCDLMWSDPDEIEGWNLSPRGAGYLFGGDVVDDFNRKNNIELICRAHQLVMEGYRVMFNEQLVTVWSAPNYCYRCGNVASILELDENLTKQYKIFEAAQENKGLPAKKPIPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP-X homolog 3.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-4 (PP-X) subfamily.