PharMolix/UniProtQA huggingface dataset:
Protein: VIP1_CAEEL
Sequence: MAHKGTESKEQIWPYKITIGICAMNRKATSKPMRAIMKKIIDFYGQWVDSFIFPEQVIINEPVENWPLCHCLVSFHSTEFPLEKAIAYVKLRNPYVINNLDRQYDLLDRRTVFKILSDNGIEHPRHGYVIRGRPNEPDTELVEHPDHIEVNGEVFNKPFVEKPISSEDHNVYIYYPSSVGGGSQRLFRKINNRSSWYSPKSEVRKEGSYIYEEFIPADGTDVKVYAVGPFYAHAEARKAPGLDGKVERDSDGKEVRYPVILSNKEKQIAKKIVLAFGQTVCGFDLLRANGKSYVCDVNGFSFVKTSTKYYEDTAKILGNQIVRHYAKSKNWRVPSDMPQPPILDLGLGDDPPMITTPSGKLAELRCVVAVIRHGDRTPKQKMKLIVTDQRFFALFEKYDGYKKHEIKMKKPNQLMEVLELARALVIEKQRDRHQILEKLREGTGEEEIHKSEHDLEVCEEEMKKWEQMRTVLEMYGHFSGINRKVQMKYLKERETKTSDEELRREGPALLLILKWGGELTTAGNMQAEALGRLFRTLYPGIRRTDGKSSPEDTQGLGFLRLHSTYRHDLKIYASDEGRVQTTAAAFAKGLLALEGELTPILMQMVKSANTDGLLDDDCQARLYQTELKRYLHKALQADRDFTPQDYLELNPNGLRAITAAMEFIKNPRKMCHEIAGYVEKMCGVIVEYSQTRPTGSTLYLQESMDLAQRRWNKELREFRRKNKHGEVEFDISKIPDIYDNIKYDMEHNPDLCINNEVEFERMYVCVKNMADIVVPQEYGIKTENKMVIAQRVCTPLLRKIRNDLHRCLENKESEETQTRLDPRASQGIATPFRHVRTRLYFTSESHIHTLMNLIRYGNLCSVDDKKWQRAMNFLSGVTEFNYMTQVVLMVYEDSRKENDEADTGPRFHIEILFSPGLYPCFLTEKERIYETRFNLSTNPKPATSSRSSGRESRDTNDSASSSTEGRRPSIEKVVTVVTPTQLSTPSVTNDDLSISSNAESTAAESTGLVNTTTKTHNDSEDDLNDVESVNLVALDELNNTTKAMADDGKTAKRQRSVTGAEKSMEEGDKPHGEWKGNGVAKSGSQISVGSNEMESNNESMETVGGGKGQWVKDLLDQTKRAMAMNSIREVEPPIVIPTPVPSTTTAVVEDEASERQSRSRRYFPYRFKHHTAQLLTGMSGGGVHMQNRLISTDVLTGKFGDHDNKKNSRKDFGAGTAVLSTAVIARSSSAPRLMTYESEDFSVGEIKRFWPPLRSLETLHDSINLSQFDGFLERLIKGALTPLPSPPKTPLPSALSCDAINKTPTQDEVEKVIGKLAPTSSTD
What is the function of this protein?
Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4.  PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis.  Phosphorylates inositol hexakisphosphate (InsP6) at position 1 to produce PP-InsP5 which is in turn phosphorylated by IP6Ks to produce (PP)2-InsP4.  Alternatively, phosphorylates PP-InsP5 at position 1, produced by IP6Ks from InsP6, to produce (PP)2-InsP4.
What are the official names of this protein?
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase, InsP6 and PP-IP5 kinase.
What is the protein family that this protein belongs to?
Belongs to the histidine acid phosphatase family. VIP1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: RL27_BORPA
Sequence: MAQKKGGGSTRNGRDSESKRLGVKVYGGQSILAGSIIVRQRGTRFHPGVNVGVGKDHTLFALANGKVHFSVKGALNKPTVSVVAAE
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: RISB_CALS8
Sequence: MRTFEGSFCGKDLKLAIVVSRFNSFITDELLKGCLDGLSRHDVDSENIDVYYVPGAFEIPLVAKKLAKSKKYNAIIALGAVIRGSTPHFEYVSAEVSKGIANVSLEQEVPVIFGVLTCDTVDQAIERAGTKAGNKGFDAALSALEMANLMKNISES
What is the function of this protein?
Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate.  This is the penultimate step in the biosynthesis of riboflavin.
What are the official names of this protein?
6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, LS, Lumazine synthase.
What is the protein family that this protein belongs to?
Belongs to the DMRL synthase family.
Protein: SYT_PYRIL
Sequence: MRVLYIHAERFTWDVKDPASDIRDEPISGKANNALVIFATVERGDIPDEGFLRQIARDIIDVANKVKASSIVIYPYAHLSSELARPYVAREVLNKLYEVVKSEFHGEVYKAPFGYYKAFEIKCFGHPLSELSRSFKPEGAKVEKKVEERRDVYIVLTPSGEEYNPADFNYDKFEDLKALVDKEVFKKELSGGSEPRYLDYLRKFGFEWESMSDVGHMRYAPEATIMIELVEDYAYMVAKSLGIPVFKIRGTNMFKLSETAIESHARLFGERLYVVESDTDLILRYAACFQQFAMVKDWVISYKHLPFGVIEIADSYRHEQPGETVLLFRLRRFFMPDLHIFTRDMAEAIDISFKLHEVIFREIEKLGRTYVSLYNVTEEFYKEYKNYLIELAKREGKPILVRILPGQKYYWVLNVEFHIIDELGRPREIATFQIDIGNAKRFGIKYVDENNQVRYPVIIHTAILGSVERYLYVVFDTMAKAEKAGKIPRLPTWLSPVQVRIIPITRDNLKYAVEIADKLETEGIRVDIDDRDETLSKKIRDAEVSWIPYICVVGSKEETEGVLSVRERGGGQYKTTPEELIKKIKEETRGYPNRPLYMPRFLSQRPSRG
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGC_BRUC2
Sequence: MKPKIFIDGEHGTTGLQIRTRLAERDDLEVISIPEAERRNKDLRADYLRAADIAILCLPDDASKEAVSLLEGHNSTRIIDTSTAHRVHPDWAYGFAELAKGQRERIAEARLVANPGCYPTGAIALVRPLRDAGLLPADYPVSVNAVSGYTGGGKQLIAQMEDRNHPDYLAANNFLYGLPLKHKHVPELQLHGRLDRRPIFSPSVGRFPQGMIVQVPLFLSELEGSPSLAKVHAVLTEHYAGQDIVEVVPLEESAKLPRVDAEELAGKDGMKLFVFGTEDHGQVNLVALLDNLGKGASGAAVQNMNLMLGK
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEM1_LYSSC
Sequence: MHTIVVGLNYKTAPVEIREKLSFIESELPQAMEALQKQKSILENVIVSTCNRTEIYAVVDQLHTGRHFVKQFLADWFDLPVETFSSYLTIREEDEAVEHLFKVTAGIDSMVLGETQILGQVKKSFLSGQEIGTTGTVYNQLFKQAVTFAKRAHNETAIGENAVSVSYAAVELAKKIFGSLQRKHVAILGAGKMGELAIENLYGSGVGKVTVINRTFEKAESLAAKFHGQAKSMKELQCSLLEADILITSTGATDYVIDYELMQFVERLRKGKPLFMVDIAVPRDIDPRVGDLPNVFLYDIDDLQGIVEANLAERERAAADITDMIGHEVIQFKDWVSTLGVVPVISALRKKANRIQEETMTSIENKMPDLTERERKILSKHTKSIINQLLKEPILQAKEMANSPKANEQLRLFQQIFGIEEAVEAEVQEMTKQELERKERAQATQTSAEPKYSF
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: LEUC_BACSU
Sequence: MMPRTIIEKIWDQHIVKHGEGKPDLLYIDLHLIHEVTSPQAFEGLRQKGRKVRRPQNTFATMDHNIPTVNRFEIKDEVAKRQVTALERNCEEFGVRLADLHSVDQGIVHVVGPELGLTLPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLSTQTLWQQRPKTLEVRVDGTLQKGVTAKDVILAVIGKYGVKFGTGYVIEYTGEVFRNMTMDERMTVCNMSIEAGARAGLIAPDEVTFEYCKNRKYTPKGEEFDKAVEEWKALRTDPGAVYDKSIVLDGNKISPMVTWGINPGMVLPVDSEVPAPESFSAEDDKKEAIRAYEYMGLTPHQKIEDIKVEHVFIGSCTNSRMTDLRQAADMIKGKKVADSVRAIVVPGSQSVKLQAEKEGLDQIFLEAGFEWRESGCSMCLSMNNDVVPEGERCASTSNRNFEGRQGKGARTHLVSPAMAAMAAIHGHFVDVRKFYQEKTVV
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase, Superoxide-inducible protein 10, SOI10.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: RL9_RICCN
Sequence: MEIILIKPVRKLGKIGDILKVADGFGRNYLLPQKLAIRATEPNKELIVKQKHEFEAKDKQIREEVEKINALIKDQQLVFIRQTSNDGKLFGSVTNKEIADKLSENISYNISHSNIILDKQIKSTGIYTVEIRLHAELNAIVTVIVARSESEAQDYLREQKTETSEDLAELA
What is the function of this protein?
Binds to the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L9.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL9 family.
Protein: CYCL_DROME
Sequence: MEVQEFCENMEEIEDENYDEEKSARTSDENRKQNHSEIEKRRRDKMNTYINELSSMIPMCFAMQRKLDKLTVLRMAVQHLRGIRGSGSLHPFNGSDYRPSFLSDQELKMIILQASEGFLFVVGCDRGRILYVSDSVSSVLNSTQADLLGQSWFDVLHPKDIGKVKEQLSSLEQCPRERLIDAKTMLPVKTDVPQSLCRLCPGARRSFFCRMKLRTASNNQIKEESDTSSSSRSSTKRKSRLTTGHKYRVIQCTGYLKSWTPIKDEDQDADSDEQTTNLSCLVAIGRIPPNVRNSTVPASLDNHPNIRHVLFISRHSGEGKFLFIDQRATLVIGFLPQEILGTSFYEYFHNEDIAALMESHKMVMQVPEKVTTQVYRFRCKDNSYIQLQSEWRAFKNPWTSEIDYIIAKNSVFL
What is the function of this protein?
Putative transcription factor involved in the generation of biological rhythms.  Activates cycling transcription of Period (PER) and Timeless (TIM) by binding to the E-box (5'-CACGTG-3') present in their promoters.
What are the official names of this protein?
Protein cycle, Brain and muscle ARNT-like 1, BMAL1, MOP3.
What are the subcellular locations of this protein?
Nucleus.
Protein: F16PC_BACVZ
Sequence: METKYLDLLAQKYDCEEKVVTEIINLKAILNLPKGTEHFVSDLHGEYQAFQHVLRNGSGRVKEKIRDIFSGVIYDREIDELAALVYYPEDKLKLIKHDFDTKEALNEWYKETIHRMIKLVSYCSSKYTRSKLRKALPAQFAYISEELLYKTEQAANKEQYYSEIIEQIIALGQADKLITGLAYSTQRLVVDHLHVVGDIYDRGPQPDKIMEELINYHSVDIQWGNHDVLWIGAYSGSKVCLANIIRICARYDNLDIIEDVYGINLRPLLNLAEKYYDDNPSFRPKADENRPEDEIKQITKIHQAIAMIQFKLESPIIKRRPNFNMEERLLLEKIDYDRNEITLNGKTYQLENTCFATVNPKQPDELLEEEAEVMDKLLFSVQNSEKLGRHMNFMMKKGSLYLKYNGNLLIHGCIPVDENGSMETMMIEDKAYAGRELLDVFERFLREAFAHPEETDDLATDMTWYLWTGEYSSLFGKRAMTTFERYFIKEKETHKEKKNPYYYLREDEAACRNILMEFGLNPDHGHIINGHTPVKEIEGEDPIKANGKMIVIDGGFSKAYQSTTGIAGYTLLYNSYGMQLVAHKHFNSKAEVLSTGTDVLTVKRLVDKELERKKVKETNVGEELMKEVAILEKLREYRYMK
What are the official names of this protein?
Fructose-1,6-bisphosphatase class 3, FBPase class 3, D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3.
What is the protein family that this protein belongs to?
Belongs to the FBPase class 3 family.
Protein: SEGN_PIG
Sequence: MDSACKPTQRRLDAAGFWQIWQRFDADEKGYIEEKELDAFFHHVLTKLGTDDAVMEENVWKMKQQFMAAHDVSKDGHIQMKELACLFLSEDENFLLLFRQETPLDSSVEFMQIWRKYDADSSGFISAAELCNFLRDLFLHHKKAISEAKLEEYTGTMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDACSTEERKRDFEKIFAHYDVSKTGALEGPEVDGFVKDMMELVQPSISGVDLDKFREILLRHCDVNKDGKIQKSELALCLGLKINP
What are the official names of this protein?
Secretagogin.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cytoplasmic vesicle, secretory vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Predominantly cytoplasmic. A small proportion is associated with secretory granules and membrane fractions (By similarity).
Protein: H2A1P_MOUSE
Sequence: MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHHKAKGK
What is the function of this protein?
Core component of nucleosome.  Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.  Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.  DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
What are the official names of this protein?
Histone H2A type 1-P.
What is the protein family that this protein belongs to?
Belongs to the histone H2A family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RL27_CORDI
Sequence: MAHKKGASSSSNGRDSEAKRLGVKRFGGQQVNAGEILVRQRGTKFHPGENVGRGGDDTLFALKAGAVEFITKRNRRLVNIVENETVDA
What are the official names of this protein?
50S ribosomal protein L27.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL27 family.
Protein: 238R_IIV6
Sequence: MAFNGIERFYVKELKKLEFSSIIELQLAEEELIRDFGTLNTIHNNDSGVFGNIDVQITDLRKKKKKIMDKIYILPPRKEILDSAMNESKIKLDISWFFDNYMDQELTNVMNYFDGEEPIHINTVVLEWFGYEGDLRTQKRKFIDMLKRNSIPYKELTSKEEIELYPTIKEEILSLPHKGAIACSKWLVMKPYDIKIAMLRLNTKNSQIIKQYYIKMEELVRLYAQYTTLFIEKEKEQMSREMNSLQLMMEEMKIANLKQEEERKLDRLMLTESRNMLQTMGIEIKTVKYNNNNLIDQNNELLERVDEVLHKVDVVQTKLNISVEDRAPQPDKNKRRERFLLLKRNDENYPYYTIRAQDINAKKALKRQKDMFSDVTILLDLICHPNTKTFYVRIKDDLKKKGVEFHLCEISIEDSQITEQDLVEAMMKINDEKREIKNEK
What are the official names of this protein?
Putative MSV199 domain-containing protein 238R.
What is the protein family that this protein belongs to?
Belongs to the IIV-6 006L/238R/313L/468L family.
Protein: MURC_RHIME
Sequence: MKMPKTIGLVHFIGIGGIGMSGIAEVLHNLGHRVQGSDQADSANVQRLREKGISISIGHKAENLGDAEVVVVSTAIKKDNPELIAAREKFLPVVRRAEMLAELMRFRNAIAIGGTHGKTTTTSMVAALLDAGGLDPTVINGGIINAYGTNARMGAGEWMVVEADESDGTFLKLPADIAVVTNIDPEHLDHYGSFDAVRAAFRQFVENVPFYGFGVLCLDHPEVQSMVGKIEDRKVVTYGENPQADVRFHNIRMDGATSIFDIEIRRRRTGQVIEIKDLRLPMPGRHNVSNATAAVAVAQRLGIKPEDIARGLATFGGVKRRFTLTGEWNGARIFDDYGHHPVEIRAVLRAAREACQGRIVAVHQPHRYSRLSSLFEDFTSCFNDADTILLAPVYAAGEEAIEGVSSEALVDRIKAAGHRDARHVPGQEALAPVIAKIAQPGDFVVLLGAGSITYWAAALPKQLAEISGNRA
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylmuramate--L-alanine ligase, UDP-N-acetylmuramoyl-L-alanine synthetase.
What is the protein family that this protein belongs to?
Belongs to the MurCDEF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MMS22_MOUSE
Sequence: MDGCSAASTFLTDSLELELGTEWCKPPCFSCAFDNREGKFSGESYLASGALKRLILNLDPLPTNFEEDTVELFGFQWVTETALVYSCRELFHLFRQQIFNLESLVQVSCDFGKIATLHAKADSIRQQCVVFLHYIKVFIFRCLKVQEAESHSRPAHPYEALEAQLPSMLVDELRGLLLYIGHLAALPSVTVGAFVNQNQMKLFPPSWHLLHLYLDTHWLVLEILHILGEKLKQVVYGRQFIGQAGDNLTNVSLFEEHCEHLFCDLICLSLNRFDKVMPSEALLISHCPCSCVKELWVLLIHLLDHRRKWSVADSFWNWLNKLLRTLFEKSSDQRRSSVSLTQAKDPLGFSWWISVHVASLYQIDRHGVSDKMKQMESNWSFIEELLKRSVTVQDSILEEQLRMHLHCCLTLCDFWEPNISVVTILWEYYSKNLNSSFSISWLPLKGLTNIIKSPLSMLTLVRNCCSDKQDPDLYKSSSSYIIFLCILAKVVKKAMRTSGPHPWKQVKGRIYSKFHQKRMEELTEVGLQNFFSLFLLLAAVAEIEDVASHVLDLLRFLRPASMSSHGALVWKGQMAFLLMYAQKNLDIGVWAEKLSCEFQEKAKEFLVSKNDEMVQRHALWTLLCIYIDGVQEVFETSSCLYPSHEHLLNDGFSMLLPACRESELRTVLNFLQAVLARIRSVHQQLCQELQRENVDLTVQSSLSAKERPLAAVAGALWRHFFSFLKSQRMTQVVPLSQLADAAADFTLLAVDMPNTAPPDLQPQPVISIIQLFGWDDIIWPQVVARYLSHLLQNSTVYEALSQSSCVSSQSLTIRSWVRCVLQMHIKHLSDPDLLIDVNPEQAVEKEYMEQLAEMTRLLFTLSEVKSVFSKAQIEQLPSPDDPKQALIQFLEAVGVTYRTLQTFSDKSAMVTKSLEYLGEVLKYIKPYLGKKVSSAGLQLTYGIMGILVKSWAHIFATSKAQKLLFRIIDCLLLPHTVLQQDKELPGPMLTAIQKTLPLYLQGICIVCCQSQNPNAYLNQLLRNVIEQYIGRFLPTSPCVSDLGQHPVLLALRNPASVPSMTPLRKHTVHAIRKSYLEFKGSSPPPRLASVLAFVLQLFKDTEMGACDLELLLPGILKCLVLVNEPQVKKLATENLQCMVQTCQVGSEGGPATQLTSLFRQFIQDYGMQYSYQVYSILETVATLNQHVVIQLIPTLTQSLKDSELKWGLGRNIAQREAYSRLLSGLGQVGQGEKQRLEK
What is the function of this protein?
Component of the MMS22L-TONSL complex, a complex that promotes homologous recombination-mediated repair of double-strand breaks (DSBs) at stalled or collapsed replication forks.  The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication.  It mediates the assembly of RAD51 filaments on single-stranded DNA (ssDNA): the MMS22L-TONSL complex is recruited to DSBs following histone replacement by histone chaperones and eviction of the replication protein A complex (RPA/RP-A) from DSBs.  Following recruitment to DSBs, the TONSL-MMS22L complex promotes recruitment of RAD51 filaments and subsequent homologous recombination.  Within the complex, MMS22L acts by binding ssDNA.
What are the official names of this protein?
Protein MMS22-like, Methyl methanesulfonate-sensitivity protein 22-like.
What is the protein family that this protein belongs to?
Belongs to the MMS22 family. MMS22L subfamily.
What are the subcellular locations of this protein?
Nucleus. Chromosome. Note=Localizes to DNA damage sites, accumulates at stressed replication forks. Recruited to stalled or collapsed replication forks; directly binds replication protein A complex (RPA/RP-A)-coated single-stranded DNA (ssDNA).
Protein: TRMFO_STAHJ
Sequence: MSQTVNIVGAGLAGSEAAYQLAQRGIKVNLIEMRPVKQTPAHHTDKFAELVCSNSLRGNALTNGVGVLKEEMRRLDSLIISAADKARVPAGGALAVDRHDFSGYITETLRNHPNVTVINEEINSIPEGYTIIATGPLTTENLAKEIVDITGKDQLYFYDAAAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEEEFNRFYDAVLEAEVAPTNEFEKEKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPFAVVQLRQDDAAGTLYNIVGFQTHLKWGAQKEVIRLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELIKEDRIQFAGQMTGVEGYVESAASGLVAGINLAHKLLDKGEVIFPRETMIGSMAYYISHAKNEKNFQPMNANFGLLPSLEKRIKDKKERYEAQANRALEYLENYKKTL
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYFB_BURMA
Sequence: MQFPESWLRTFVDPQLTTDELSHALTMAGLEVESLRPAAPPTEKIVVGRVLEVVKHPDADKLNVCQVDAGTGATLQIVCGAPNVAPGIKVPVALVGAKLPPAEEGGAPFAIKLSKLRGVESQGMLCSARELKLSEDHSGLMILPEGTPVGQDIREALNLDDTVFEIKLTPNKADCLSVFGIARETAAITGAPLAAPDIRPVLAELTETLPVKISAPDLCGRFSGRVIRGVNARAKTPHWMVERLERAGQRSVSALVDISNYVMFELGRPSHVFDLDKIHGGIDVRWGKRGESLKLLNGNTIELDETVGVISDGAQVESLAGIMGGDSTAVTLDTTNIYLEAAFWWPDSIRGRARKYNFSTDAAHRFERGVDYSTTVEHVERITQLILDICGGQAGPVDDQIVSLPQRAPVSMRASRANRIIGVEIGEDEIAQIFTRLGLAFERDGDVFRVTPPPHRFDIEIEEDLIEEVARIYGFEKIPARPPVAKSEMRATDETRRSVHAIRHALAARDYAETVNFSFVDAEWERDFAGNDNPVRLLNPIASQLSVMRTTLFGSLVGVLRHNLNRRAERVRVFEAGRVFVADPSVKAGELAVEGYAQPKRIGALAYGPVVEEQWGTATRQVDYFDVKGDLEALLAPVPARFVKAEHPALHPGRSARIEVDGHAVGWIGELHPRLMQKYELPHAPVMFEIDTDALVARALPAPSEVSKFPPVRRDIAVVVDQKVEVQALFDEMKKALADDACKFVQRVALFDEFRAKSNTSGGLSAHEKSLAFRVTLQDAAGTLQDETVDQAIQTLVDRMARVYGARLRG
What are the official names of this protein?
Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL17_CLAM3
Sequence: MPKPTKGPRLGGGPAHERLMLANLAQSLFEHKSIKTTETKAKRLRPVAERLVTFAKRGDLHARRRVMGIIPSKSVVHELFTEIAPLVAERDGGYTRITKLGFRKGDNAPMVQIELVLEPVTPKVRSSRTSTATAPAAAAPAAEAPAEESDVPVEETDAVEHTDETPAETTDEAAAEVEADAAEKSDK
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: LSPA_BURP1
Sequence: MAKTLSKSSGGALAPWLGISLIVILFDQLTKIAVLKTFAYGAMHALTPFFNLTLIYNRGAAFGFLATAGGWQRWAFTALGIGATLVICYLLKRHGHQRLFSLSLALILGGALGNVIDRLIYGHVIDFLDFHVGAWHWPAFNLADSAITVGAVLLIYDELRRVRGAR
What is the function of this protein?
This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
What are the official names of this protein?
Lipoprotein signal peptidase, Prolipoprotein signal peptidase, Signal peptidase II, SPase II.
What is the protein family that this protein belongs to?
Belongs to the peptidase A8 family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: S100B_RABIT
Sequence: MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVAMVTTACHEFFEHE
What is the function of this protein?
Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain.  Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer (By similarity).  Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites (By similarity).  Acts as a neurotrophic factor that promotes astrocytosis and axonal proliferation.  Involved in innervation of thermogenic adipose tissue by acting as an adipocyte-derived neurotrophic factor that promotes sympathetic innervation of adipose tissue (By similarity).  Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase (By similarity).  Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling (By similarity).  Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization.  May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity (By similarity).
What are the official names of this protein?
Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B.
What is the protein family that this protein belongs to?
Belongs to the S-100 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SSUB2_XANAC
Sequence: MAGLASGATTACRATPMSAATTGLPLRVRGIAKRYGDSDVLRGIDLEIAPSACVAIVGRSGCGKSTLLRVIAGLETADVGTVDSGRAPLAAQRDAVRLMFQDARLLPWKRVIDNVALGLGRAGRAQAQQALDAVGLGTRGNAWPSALSGGQRQRVALARALVHRPRLLLLDEPLGALDALTRIEMQQLIVQLWRQHGFTLVLVTHDVAEASALADRIVVLEHGKVGLDVAVPVPHPRAPGLPALASIQAQVLSRLLGTTQVPEPAAPKAQTRHGPPRGATAQDTSPLQRIL
What is the function of this protein?
Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import.  Responsible for energy coupling to the transport system.
What are the official names of this protein?
Aliphatic sulfonates import ATP-binding protein SsuB 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Aliphatic sulfonates importer (TC 3.A.1.17.2) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: UFM1_SALSA
Sequence: MSKVTFKITLTSDPRLPYKVLSVPESTPFTAVLKFAAEEFKVPAATSAIITNDGIGINPAQTAGNVFLKHGSELRIIPRDRVGGRGVGTDRPSSSSSKTQ
What is the function of this protein?
Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer.  The so-called ufmylation, requires the ufm1-activating E1 enzyme uba5, the ufm1-conjugating E2 enzyme ufc1, and the ufm1-ligase E3 enzyme ufl1.  Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.
What are the official names of this protein?
Ubiquitin-fold modifier 1.
What is the protein family that this protein belongs to?
Belongs to the UFM1 family.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm.
Protein: AROA_GEODF
Sequence: MQIHTSKPAKTVRGEITVPGDKSISHRSIMLGSLARGITTVKGFLRGEDNLATLNAFRAMGIIVHDDGETLKIEGNGLHGLGEPADVLDCGNSGTSMRLMTGLLSGQRFFSVLTGDQYLRKRPMKRVLEPLNLMGATVFGRAGGDKAPLAIVGTSLKGIAYQSPVSSAQVKSAILLAGMYADGETQVTEPHLSRDHSERILRYFGADIETYSGGTRIRGGRELEGREIIVPGDISSAAFFMVAALIVPGSELLIKGVGVNPTRTGIIDILQAMGGDITLQNCRESSGEPVADILVKSSRLKGIEVGGDLVPRAIDEFPVICVAASLAEGKTVIRDAKELRVKETDRIKAMAFNLQKAGVAVVETENGMDVTGMEKLEGCTAESFGDHRIAMSMLIAGLAARDQITVNDTECIGTSFPNFTALLQGVTVI
What is the function of this protein?
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
What are the official names of this protein?
3-phosphoshikimate 1-carboxyvinyltransferase, 5-enolpyruvylshikimate-3-phosphate synthase, EPSP synthase, EPSPS.
What is the protein family that this protein belongs to?
Belongs to the EPSP synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RSMH_ANADE
Sequence: MSADFRHEPVLANEVLELLRPRPGELFLDGTLGGGGHSGLLLEAGARVIALDKDPRALAAATARLARFGEAFRAVRSDFRDAKNVLEALGIGAVDGALVDLGVSSPQLDEAERGFSFSRPGPLDMRMGDTGETLEDLLRRIDERELARILREYGEEPFARPVARAIKAALEAEAPLDTARLAEVVAGAIPRKAWPHRIHPATRTFQALRIAVNDELGALAAWLDGLPGVLAPGGRAAAISFHSLEDRMVKEKFRALTQACTCPPDLPVCACGAKASFAAITRKAVKASDDEIARNPRARSARLRAVEKLR
What is the function of this protein?
Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase H, 16S rRNA m(4)C1402 methyltransferase, rRNA (cytosine-N(4)-)-methyltransferase RsmH.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmH family.
What are the subcellular locations of this protein?
Cytoplasm.