PharMolix/UniProtQA huggingface dataset:
Protein: PCKA_YERE8
Sequence: MSVKGITPQELAAYGIHNVSEIVYNPSYDLLFQEETKPTLEGYERGTLTNTGAIAVDTGIFTGRSPKDKYIVRDAITQDTVWWADQGKGKNDNKPLSQETWTHLKGLVTNQLSGKRLFVVDTFCGANADTRLQVRFVTEVAWQAHFVKNMFIRPTDEELAHFEPDFIVMNGAKCINPNWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVGEKGDVAIFFGLSGTGKTTLSTDPKRKLIGDDEHGWDDDGVFNFEGGCYAKTIKLSEEAEPDIYHAIKRDALLENVVVLPDGTVDFNDGSKTENTRVSYPIYHIENIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTANQTQYHFLSGFTAKLAGTERGVTEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAVGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGEIDKAETFTLPIFDLAVPMALPGVDPAILDPRDTYADVAQWQEKAEDLAKRFTTNFDKYTDTPAGAALVSAGPKI
What is the function of this protein?
Involved in the gluconeogenesis.  Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
What are the official names of this protein?
Phosphoenolpyruvate carboxykinase (ATP), PCK, PEP carboxykinase, PEPCK.
What is the protein family that this protein belongs to?
Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ARGR_AERS4
Sequence: MKHNDKQEKLAKAFKALLKEERFGSQAEIVTALQEMGFENINQSKVSRMLSRFGAVRTRNAKMEMVYCLPVELGVPTTSSPLKNLVLDVDHNGALVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFITPTSDTDIEELYLSALELFEQTP
What is the function of this protein?
Regulates arginine biosynthesis genes.
What are the official names of this protein?
Arginine repressor.
What is the protein family that this protein belongs to?
Belongs to the ArgR family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFA_EDWI9
Sequence: MALTKAEMSEHLFEKLGLSKRDAKDLVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKCRVENATPKD
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit alpha, IHF-alpha.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: DOK4_PONAB
Sequence: MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDAARFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAAQGPEQQVASQFLWAWSDTGRICASTVLLASLAVGVLSRGDIWLTPQVKIWF
What is the function of this protein?
DOK proteins are enzymatically inert adaptor or scaffolding proteins.  They provide a docking platform for the assembly of multimolecular signaling complexes.  DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity).  Putative link with downstream effectors of RET in neuronal differentiation.  May be involved in the regulation of the immune response induced by T-cells (By similarity).
What are the official names of this protein?
Docking protein 4, Downstream of tyrosine kinase 4.
What is the protein family that this protein belongs to?
Belongs to the DOK family. Type B subfamily.
Protein: SYC_RHOPB
Sequence: MALRLYDTLTKEKRDFAPLDPSNVRMYVCGPTVYDFAHIGNARPVIVFDVLFRLLRHLYGPDHVKYVRNITDVDDKINDRATRDFPGLPLNEAIRKVTEQTEKQFHDDVDALGCLRPTIEPRATEHIGEMRSIIDRLVEGGFAYVAEDHVLFSPQAMNAADGILPRYGSLANRSLDEMIAGARVDVAPYKRDVTDFVLWKPSKPGEPSWPSPAGIATQGRPGWHIECSAMAWKHLGEKFDIHGGGIDLVFPHHENEVAQSCCAFHTDRMATTWMHNGFLQVEGEKMSKSLGNFLTISDQRDQWGPAVLRLNMLKTHYRQPIDWTQHNLSETGRELDRWFEFLESASGGDPNDANDVMSALADDLNTSAAITALRVQFKNKNSAALRSGLDLLGIPIGREFIQGRKHVRLYAEGAFVAAGGGTATFSTASSSVERSDIQQLIDARAAARARKDFKESDRIRDQLAAMGVVLKDGKDADGKPTTTWEIAR
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TTCA_ACIBT
Sequence: MYAPVESNEGFNFKPELPTSSAYYRLLKKLRRQVGHAIRDFNMIEDGDKVMVCVSGGKDSYTLLDILLQFKRIAPINFDIVAVNLDQKQPGFPEDVLPRYMEENNIPYYILEKDTYSITKRLTPEGKTYCAVCSRLRRGSLYGFAQEIGATKVALGHHRDDIIATFFLNLFHGGSLKAMPPKLLSSDKKNILIRPLAYVEEKDIIKYAELRKFPIIPCNLCGSQENLQRAMINEMLREWDRQYPKRLHSIFGALQNVSPSQLADRDLFDFEVLDSQRELDFKDPEELKKRLDVVNLSFAAE
What is the function of this protein?
Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32).  The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.
What are the official names of this protein?
tRNA-cytidine(32) 2-sulfurtransferase, Two-thiocytidine biosynthesis protein A, tRNA 2-thiocytidine biosynthesis protein TtcA.
What is the protein family that this protein belongs to?
Belongs to the TtcA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RLMN1_PARUW
Sequence: MKIPPISILSHTSESYANAISHELGKGFQHAKLVYQEWFRRGNISGLNPAFKNAQALLQNILSLTDFSFLPISQNLTDGQTGKFLIKTIDDLDIKSVLIPMQAGGTLCISSQIGCQMGCAFCETGRMGLLRNLTTQEILSQLFIAKFRLHFSVRNIVFMGMGEPFDNYDTVMHAFRILTDSHGFGLGNNRITISTSGCLEGIYRLLQETTPLPNLAVSLNAPNDELRNKLMPINKKYPLKELYQAIYDFCKQTSKQVLIAYVLIKEQNDSIEHAKQLTNFLSGLNVKINLIPYNPQSRDRFQSPEQSTLENFTSYLREKGFYTLLRQTKGQKIMAACGQLGNLELKRKKPFILPILKE
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.
What are the official names of this protein?
Probable dual-specificity RNA methyltransferase RlmN 1, 23S rRNA (adenine(2503)-C(2))-methyltransferase 1, 23S rRNA m2A2503 methyltransferase 1, Ribosomal RNA large subunit methyltransferase N 1, tRNA (adenine(37)-C(2))-methyltransferase 1, tRNA m2A37 methyltransferase 1.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NADD_XYLFM
Sequence: MPSLHIFYGGTFDPVHVGHLAIARAAHAALQAPIALIPSADPPHRPTPGSSSMDRLRMLQLAVSKEPGLSADPRELRRAARQNRPSYTVDTLTEVRSELGPKTSIIWLLGADAFVNLSNWKDWQMLPELTHLVVANRPGITLQTQLPPKMATVFNHRWVQDPATLRKTPHGHLWLLNQHPNPSSASKVRAAISAAAHWEADLTPEVAQYIRTHGLYGIHDIN
What is the function of this protein?
Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
What are the official names of this protein?
Probable nicotinate-nucleotide adenylyltransferase, Deamido-NAD(+) diphosphorylase, Deamido-NAD(+) pyrophosphorylase, Nicotinate mononucleotide adenylyltransferase, NaMN adenylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the NadD family.
Protein: XOL1_CAEEL
Sequence: MQVEANSERRVKILGIDRSENSPVLTYMETEDDPNFRNSKLAAAPHTVHMMDSGFLAINRQCLVKGKAILAREPKSSNEHMIDDLPKHAHDQHTLSILRDFIDQLKLHNVYEINFYDPLDSSGKLAVIPMLIALWKCMLASETDICDQEVLKSIMNSVIAKFELQIPCKNAVIDATLSGSREEVHIIAEDGSLENSNGTTEHFNKKHDLVFVKTDLHPEDFTPQMFPSQAKAKLLRDAFNNEEDEDTFPDILVPAYMTAHSKNRVRQEDYTCLEVEFDSQVALEKLMNEHEQVEGFEVQQGGILVALKKDSFFDDELIEKIAIAIATESRQSVSSVSFDLLKLGPGASLVTLANSRRFEPECRVVLQIEVKPVSPGETSSEGISDEHHYEEYDEDDIMEEEEAPSARQDDTYDEDEE
What is the function of this protein?
Sex-determining factor that is required for sexual differentiation and X chromosome dosage compensation to promote male development (PubMed:7813020, PubMed:9217163, PubMed:33372658).  High expression during gastrulation triggers male development, while low expression at that time triggers hermaphrodite development.  Although related to GHMP kinase, its mode of action remains unclear.
What are the official names of this protein?
XO lethal protein 1.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Xol-1 subfamily.
What are the subcellular locations of this protein?
Nucleus.
Protein: CYB_CHOPC
Sequence: MTNIRKTHPLMKIINHSFIDLPAPSNISSWWNFGSLLGTCLIIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMYLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVQWIWGGFSVDKATLTRFFAFHFILPFIVAALAGVHLLFLHETGSNNPSGLSSDADKIPFHPYYTIKDILGVLLLMLALTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILVLAIIPLLHTSKQRSMMFRPFSQCMFWILVADLITLTWIGGQPVEHPFIIIGQLASILYFLLILILMPITSLLENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: HA10_MOUSE
Sequence: MGAMAPRTLLLLLAAALAPTQTQAGSHSMRYFETSVSRPGLGEPRFIIVGYVDDTQFVRFDSDAETPRMEPRAPWMEQEGPEYWERETQRAKGNEQSFHVSLRTLLGYYNQSESGSHTIQWMYGCKVGSDGRFLRGYLQYAYDGRDYIALNEDLKTWTAADVAAIITRRKWEQAGAAEYYRAYLEAECVEWLLRYLELGKETLLRTDPPKTHVTHHPGSEGDVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVYHEGLPEPLTLRWEPPPSTDSIMSHIADLLWPSLKLWWYL
What is the function of this protein?
Involved in the presentation of foreign antigens to the immune system.
What are the official names of this protein?
H-2 class I histocompatibility antigen, Q10 alpha chain.
What is the protein family that this protein belongs to?
Belongs to the MHC class I family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: ISS_ECOLX
Sequence: MQDNKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSPIGQRKLLMQPKFVGGAENVVKTETQQTFVNALPGFITFGIYTPRETRVYCSQ
What is the function of this protein?
Increases serum survival and confers group II surface exclusion.
What are the official names of this protein?
Protein iss.
Protein: COAX_MYCTU
Sequence: MLLAIDVRNTHTVVGLLSGMKEHAKVVQQWRIRTESEVTADELALTIDGLIGEDSERLTGTAALSTVPSVLHEVRIMLDQYWPSVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAAYDRFRKAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELARPRSVVGKNTVECMQAGAVFGFAGLVDGLVGRIREDVSGFSVDHDVAIVATGHTAPLLLPELHTVDHYDQHLTLQGLRLVFERNLEVQRGRLKTAR
What is the function of this protein?
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
What are the official names of this protein?
Type III pantothenate kinase, PanK-III, Pantothenic acid kinase.
What is the protein family that this protein belongs to?
Belongs to the type III pantothenate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTM1_YEAST
Sequence: MTEDKSQVKIRFFTREKDELLHVQDTPMYAPISLKRYGLSEIVNHLLGSEKPVPFDFLIEGELLRTSLHDYLTKKGLSSEASLNVEYTRAILPPSYLNSFSNEDWVSSLDVGDGSKHIISGSYDGIVRTWDLSGNVQKQYSGHSGPIRAVKYISNTRLVSAGNDRTLRLWKTKNDDLKLTSQQQAQEDDDDEVNIEDGKTLAILEGHKAPVVSIDVSDNSRILSASYDNSIGFWSTIYKEMTVVDPLEDINNPNNKISTAARKRRKLTMKDGTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTARCIDTRTTSYSLLSIAQLSTLNLLACGSSARHITLHDPRVGASSKVTQQQLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRSTSPMYTITREDKSVQKGVNDKVFAVKWAEKVGIISAGQDKKIQINKGDNIFKN
What is the function of this protein?
Component of the NOP7 complex, which is required for maturation of the 25S and 5. 8S ribosomal RNAs and formation of the 60S ribosome.
What are the official names of this protein?
Ribosome biogenesis protein YTM1, Microtubule-associated protein YTM1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat WDR12/YTM1 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus, nucleoplasm.
Protein: MT1C_ARATH
Sequence: MAGSNCGCGSSCKCGDSCSCEKNYNKECDNCSCGSNCSCGSSCNC
What is the function of this protein?
Metallothioneins have a high content of cysteine residues that bind various heavy metals (Probable).  Confers tolerance to cadmium (Cd) and plays a role in Cd and zinc (Zn) homeostasis (PubMed:16240177).
What are the official names of this protein?
Metallothionein-like protein 1C, MT-1C.
What is the protein family that this protein belongs to?
Belongs to the metallothionein superfamily. Type 15 family.
Protein: TATA_EHRRW
Sequence: MALGPWQIFLILVIILVLFGAGKLPDVMSDLGKGIRNLKQELKDNKLASTEDESNL
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: IXTPA_LISMO
Sequence: MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASVLNQTVIADDSGLIVDALDGAPGVYSARYAGVAHDDAKNNEKLLKNLEGVEPDKRTARFHCTLAVATPSEKTSFYTGEVEGVIAEQLCGTNGFGYDPLFFLPEFGLTMAEIPAEKKNEISHRANAIKQLEKDLVEVVEKVTKK
What is the function of this protein?
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP.  Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
dITP/XTP pyrophosphatase, Non-canonical purine NTP pyrophosphatase, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase, Nucleoside-triphosphate pyrophosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the HAM1 NTPase family.
Protein: DAPF_YERPY
Sequence: MQFSKMHGLGNDFMVVDAVTQNVYFSPELIRRLADRHTGVGFDQMLVVEPPYDPELDFHYRIFNADGSEVSQCGNGARCFARFVRLKGLTNKREISVSTQTGRMILSVTEDEQVCVNMGEPDFEPQTVPFRAAKAEKTYILRAAEHTVLCGVVSMGNPHCVMQVDDVSVANVALLGPVLENHERFPERANIGFMQVVSRDHIRLRVYERGAGETQACGSGACAAVAVGVVQDLLNENVHVELPGGSLHIRWQGPGHPLYMTGPATHVYDGFIHL
What is the function of this protein?
Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
What are the official names of this protein?
Diaminopimelate epimerase, DAP epimerase, PLP-independent amino acid racemase.
What is the protein family that this protein belongs to?
Belongs to the diaminopimelate epimerase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSB_LEPBP
Sequence: MSSRHRGRSLALMCLYQIDLVGTDPDRAMKFDWYDKKITREEKDYAVFLVKGVVENRKAIDTLIKKYSENWELSRISVVNRCILRLSILSLQKEPFLAAPVVINEAVELTKEFETEESAQFINGLLDAFYKKEILPKEPH
What is the function of this protein?
Involved in transcription antitermination.  Required for transcription of ribosomal RNA (rRNA) genes.  Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
What are the official names of this protein?
Transcription antitermination protein NusB, Antitermination factor NusB.
What is the protein family that this protein belongs to?
Belongs to the NusB family.
Protein: 17KD_RICCA
Sequence: GSQFGKGKGQLIGVGAGALLGAILGNQIGAGMDEQDRRLAELTSQRALETTPSGTSIEWRNPDNGNYGYVTPSKTYKNST
What are the official names of this protein?
17 kDa surface antigen.
What is the protein family that this protein belongs to?
Belongs to the rickettsiale 17 kDa surface antigen family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor.
Protein: GGR_METVS
Sequence: MRALEESYDVVVVGAGPAGSMSSYNASKNGAKTLLIEKAQEIGTPVRCAEAIPRIESFGINPSSEFIRSYIKGAYLVAPNGKKITVKGGKTDGYVVERKIFDKFLAIRSAKEGTKIAVKSRVTGLEKTEEGYNVFVNHLGKEYTVKTKLVIAADGVESTISEYAGLKSKKNHNEVCSCAEYEMTNVKLLDNNMMEFYFGEICPKGYIWLFPKGDTVNVGIGIIEGSKKAIEYLDDFLSNPLLEGRLKNAVPVEFKVGGDPVGGPIKKTFKDNLIVVGDAAGHVSPLTGGGISLAMDCGLIAGEVCAKSISSKNYSEEFLSQYETRWKEKHYKFLMNDLKYKTILQKLNDNELNAIADSIPENLEEVDVGKLAIKIVKKAPSLLKYFKELI
What is the function of this protein?
Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids.  Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains.
What are the official names of this protein?
Digeranylgeranylglycerophospholipid reductase, DGGGPL reductase, 2,3-bis-O-geranylgeranylglyceryl phosphate reductase, Geranylgeranyl reductase, GGR.
What is the protein family that this protein belongs to?
Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily.
Protein: RR20_TRICV
Sequence: MANNASAEKRILINERNRLQNRFYKSSVRTLTKLYLKDLEVYKISRNPSDKEKAKNRLSLVYSLIDKGSKRNVFHKNTAARKKSKLASQLKIA
What is the function of this protein?
Binds directly to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S20, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS20 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: KNOSD_ORYSJ
Sequence: MAFHGHLPHEMTMQALGADDAAVAAAAAAGGVGAGGAPAWMRYNDGSFLHLQTTSDSSASPSGAAAAAAAAAAAAAAGVQQWMGGGGGGEDAVAAAMGGGGEADAARCKAEILAHPLYEQLLSAHVACLRIATPVDQLPRIDAQLAQSQGVVAKYSALAAAAAGDDGRELDQFMTHYVLLLCSFKEQLQQHVRVHAMEAVMACWELEQNLQSLTGASPGEGTGATMSDGEDDQADSEANMYDPSLDGADNMGFGLPTESERSLMERVRQELKHELKQGYKEKLIDIREEILRKRRAGKLPGDTTSTLKAWWQSHAKWPYPTEEDKARLVQETGLQLKQINNWFINQRKRNWHSNPSSSTSVKTKRKSNAGDNNS
What is the function of this protein?
Isoform 3 acts as transcription activator, but isoforms 1 and 2 do not.
What are the official names of this protein?
Homeobox protein knotted-1-like 13, Homeobox protein OSH45.
What is the protein family that this protein belongs to?
Belongs to the TALE/KNOX homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: DECR2_ARATH
Sequence: MDSPFKPDVVRGQVALITGGGSGIGFEISSQFGKHGASIAIMGRRKQVLDDAVSALRSLGIQAIGLEGDVRKQEDARRVVEATFQHFGKLDILVNAAAGNFLAAAEDLSPNGFRTVLDIDAVGTFNMCHAALKYLKKGAPGRDSSSGGGSIINISATLHYTASWYQIHVSAAKAAVDATTRNLALEWGTDYDIRVNGIAPGPIGGTPGMSKLVPEEIENKTREYMPLYKVGEKWDIAMAALYLSCDSGKYVSGLTMVVDGGLWLSKPRHLPKEAVKQLSRAVEKRSRAKPVGLPTSKL
What is the function of this protein?
Auxiliary enzyme of beta-oxidation.  Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome.  Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA (By similarity).
What are the official names of this protein?
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing].
What is the protein family that this protein belongs to?
Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.
What are the subcellular locations of this protein?
Peroxisome.
Protein: RUVA_AGRFC
Sequence: MIGKLKGSIEEIGADYVLVDVHGVCYVAYCSARTLSKIGSVGEAVVLFIETYVREDQLKLFGFVSALEREWFNLLQSVQGVGSKVALAVLSTLSPSELANAIALQDKTMISRAPGIGPKVAVRLVTELRNKAPAFAGDASASIGLKQELGEGVASAPVADAVSALTNLGYSRDQAANAVAAALKNGGEGGDSAKLIRLGLKELSR
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: DNAA_BACHK
Sequence: MENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PKNX1_MOUSE
Sequence: MMATQTLSIDSYQDGQQMQVVTELKTEQDPNCSDPDAEGVSPPPIESQTPMDADKQAIYRHPLFPLLALLFEKCEQSTQGSEGTTSASFDVDIENFVRKQEKDGKPFFCEDPETDNLMVKAIQVLRIHLLELEKVNELCKDFCSRYIACLKTKMNSETLLSGEPGSPYSPVQSQQIQSAITGTLSPQGIVVPASALQQGNVTMATVAGGTVYQPVTVVTPQGQVVTQALSPGTIRIQNSQLQLQLNQDLSILHQEDGSSKNKRGVLPKHATNVMRSWLFQHIGHPYPTEDEKKQIAAQTNLTLLQVNNWFINARRRILQPMLDSSCSETPKTKKKPAQNRPVQRFWPDSLASGVAQATPSELAMSEGAVVTITTPVNMNVDSLQSLSSDGATLAVQQVMMAGQSEDESVDSTEDEGGALAPTHISGLVLENSDSLQ
What is the function of this protein?
(Microbial infection) In complex with PBX1, binds to the 5'-TGATTGAC-3' consensus sequence in the U5 region of Moloney murine leukemia virus and promotes viral transcription.
What are the official names of this protein?
Homeobox protein PKNOX1, PBX/knotted homeobox 1.
What is the protein family that this protein belongs to?
Belongs to the TALE/MEIS homeobox family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RHAD_CROS8
Sequence: MQRILSSWFVQGMVKATSDMWLKGWDERNGGNVSLRLDAADVEPYRDEFYPAPRCVELSQPRTELAGCWFLVTGSGKFFRNVQLDPADTLVLLQITDDGMAYHIHWGLSNGGLPTSELASHFQSHAVRKAVSGGKDRVIMHCHATNLIALSFVLELDEARFTRLLWEGSTECLVVFPDGIGIVPWMVPGTDGIGSATSEQMKTHTLVLWPHHGIFGTGPTLDEAFGLIDTAEKSAEILVKVLSMGGMKQTITREELIALGERFGVTPHAGAIAL
What is the function of this protein?
Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde.
What are the official names of this protein?
Rhamnulose-1-phosphate aldolase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. RhaD subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: AMY_THECU
Sequence: MGVRRSLAALLAALLGCATSLVALTVAASPAHAAPSGNRDVIVHLFQWRWKSIADECRTTLGPHGFGAVQVSPPQEHVVLPAEDYPWWQDYQPVSYKLDQTRRGSRADFIDMVNTCREAGVKIYVDAVINHMTGTGSAGAGPGSAGSSYSKYDYPGIYQSQDFNDCRRDITNWNDKWEVQHCELVGLADLKTSSPYVQDRIAAYLNELIDLGVAGFRIDAAKHIPEGDLQAILSRLKNVHPAWGGGKPYIFQEVIADSTISTGSYTHLGSVTEFQYHRDISHAFANGNIAHLTGLGSGLTPSDKAVVFVVNHDTQRYEPILTHTDRARYDLAQKFMLAHPYGTPKVMSSYTWSGDDKAGPPMHSDGTTRPTDCSADRWLCEHRAVAGMVGFHNAVAGQGIGSAVTDGNGRLAFARGSAGYAAFNATNTAWTRTFTTSLPDGVYCDVANGTFVDGVCDGPSYQVSGGKFTATVPANGAVALHVEAPGSCGPDGCGTPPGGGDDCTTVTARFHATVTTWYGQEVAVVGSIPELGSWQPAQGVRLRTDSGTYPVWSGAVDLPAGVGFEYKYVKLNRTAPWSGSRAATASPPWMTSGGGCSQNFYDSWR
What are the official names of this protein?
Alpha-amylase, 1,4-alpha-D-glucan glucanohydrolase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 13 family.
Protein: FLGH_SHIFL
Sequence: MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
What is the function of this protein?
Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
What are the official names of this protein?
Flagellar L-ring protein, Basal body L-ring protein.
What is the protein family that this protein belongs to?
Belongs to the FlgH family.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Bacterial flagellum basal body.