PharMolix/UniProtQA huggingface dataset:
Protein: TRPC1_RABIT
Sequence: MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEENTLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQLLLDYGCQKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCECTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEVEFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRLKLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCYLIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYLLILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFADRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLGMFLLVLFSFTIGLTQLYDKGYTPKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFSLAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDKEWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNSLKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNEIRDLLGFRTSKYAMFYPRN
What is the function of this protein?
Thought to form a receptor-activated non-selective calcium permeant cation channel.  Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors.  Seems to be also activated by intracellular calcium store depletion.
What are the official names of this protein?
Short transient receptor potential channel 1, TrpC1, Calcium influx channel TRPC1A.
What is the protein family that this protein belongs to?
Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: MERP_SALTI
Sequence: MKKLFAALALAAVVAPVWAATQTVTLSVPGMTCASCPITVKHALSKVEGVSKTDVSFDKRQAVVTFDDAKTNVQKLTKATEDAGYPSSLKR
What is the function of this protein?
Involved in mercury resistance.  Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
What are the official names of this protein?
Mercuric transport protein periplasmic component, Mercury scavenger protein, Periplasmic mercury ion-binding protein.
What is the protein family that this protein belongs to?
Belongs to the MerP family.
What are the subcellular locations of this protein?
Periplasm.
Protein: PYRF_DICT6
Sequence: MRKYDPIIVALDFPEERKALEVAEKIIPYVKNFKVGLELFSVAGPHIVKALKEMGTNVFIDLKLFDIPNTVVRTLDRLLTLDPFMVTLHILGGEEMLRESVKLVSQYKESNKTEYPYLLGVTVLTSFNEETLRRSWGISRSLPEQVLFLAQLAQETGLDGVIASPWEIELLRNNLRRPMLIVTPGIRLTKDKTDDQQRIMTPREALERGSDYLVIGRPITQSSDPYEVIRNIRSQIEDIVESRL
What is the function of this protein?
Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
What are the official names of this protein?
Orotidine 5'-phosphate decarboxylase, OMP decarboxylase, OMPDCase, OMPdecase.
What is the protein family that this protein belongs to?
Belongs to the OMP decarboxylase family. Type 1 subfamily.
Protein: BTUC_SALHS
Sequence: MLTFARQQQRRNVRWLLSLSLLVLLATLLSLCAGEQWIAPGDWLSARGELFVWQIRLPRTLAVLLVGAALALSGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPGWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSFDLRQLMYWMMGGFGGVDWQQSWLMIALIPVLIWICCQSQPLNMLALGETSARQLGLPLWFWRNLLVVATGWMVGVSVAMAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGAIALLLADVVARLALASAELPIGVVTATLGAPVFIWLLLKSAR
What is the function of this protein?
Part of the ABC transporter complex BtuCDF involved in vitamin B12 import.  Involved in the translocation of the substrate across the membrane.
What are the official names of this protein?
Vitamin B12 import system permease protein BtuC.
What is the protein family that this protein belongs to?
Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: UPP_YERE8
Sequence: MKIVEVKHPLVKHKLGLMRENDISTKRFRELASEVGSLLTYVATADLETEKVTIEGWNGPVEIEQIKGKKITVVPILRAGLGMMEGVLENVPSARISVVGVYRDEETLKPVPYFQKLVSNIDERMALVVDPMLATGGSMIATIDLLKKAGCKSIKVLVLVAAPEGIKALEAAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
What is the function of this protein?
Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.
What are the official names of this protein?
Uracil phosphoribosyltransferase, UMP pyrophosphorylase, UPRTase.
What is the protein family that this protein belongs to?
Belongs to the UPRTase family.
Protein: UTP5_YEAST
Sequence: MDSPVLQSAYDPSGQYLCYVTVALDKQRVGVQPTQRATSSGVDTVWNENFLYLEDSKLKVTCLKWVNLASSDTVAIILGMNNGEIWLYSVLANEVTYKFTTGNSYEIKDIDLMGNQLWCIDSSDAFYQFDLLQFKLLQHFRINNCVQLNKLTIVPAGDSVAQLLVASHSISLIDIEEKKVVMTFPGHVSPVSTLQVITNEFFISGAEGDRFLNVYDIHSGMTKCVLVAESDIKELSHSGQADSIAVTTEDGSLEIFVDPLVSSSTKKRGNKSKKSSKKIQIVSKDGRKVPIYNAFINKDLLNVSWLQNATMPYFKNLQWREIPNEYTVEISLNWNNKNKSADRDLHGKDLASATNYVEGNARVTSGDNFKHVDDAIKSWERELTSLEQEQAKPPQANELLTETFGDKLESSTVARISGKKTNLKGSNLKTATTTGTVTVILSQALQSNDHSLLETVLNNRDERVIRDTIFRLKPALAVILLERLAERIARQTHRQGPLNVWVKWCLIIHGGYLVSIPNLMSTLSSLHSTLKRRSDLLPRLLALDARLDCTINKFKTLNYEAGDIHSSEPVVEEDEDDVEYNEELDDAGLIEDGEESYGSEEEEEGDSDNEEEQKHTSSKQDGRLETEQSDGEEEAGYSDVEME
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 5, U3 snoRNA-associated protein 5, U three protein 5, U3 protein 5 required for transcription, t-UTP5.
What is the protein family that this protein belongs to?
Belongs to the UTP5 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Note=Associated with ribosomal chromatin, even in the absence of transcription.
Protein: ADRM1_BOVIN
Sequence: MTTSGALFPSLVPGSRGSSNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSGGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSGGPPASSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGDGASTAASPAQPIQLSDLQSILATMSVPAGPGGGQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESLPQTAEEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNSASPEQQEGDGKDKKDEEEDMSLD
What is the function of this protein?
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.  This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required.  Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.  Within the complex, functions as a proteasomal ubiquitin receptor.  Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation.  UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.
What are the official names of this protein?
Proteasomal ubiquitin receptor ADRM1, Rpn13 homolog.
What is the protein family that this protein belongs to?
Belongs to the ADRM1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RL14_LACLA
Sequence: MIQTESRLKVADNSGAKELLTIRVLGGSSRKFAGIGDIVVATVKSAAPGGAVKKGEVVKAVIVRTKSGAKRPDGSYIKFDENAAVLIRDDKTPRGTRIFGPVARELREGGYMKIVSLAPEVL
What is the function of this protein?
Binds to 23S rRNA.  Forms part of two intersubunit bridges in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL14 family.
Protein: NQRA_ALISL
Sequence: MITIKKGLDLPIAGVPTQVINDGNSITKVALLGEEYVGMRPTMHARVEDVVKKGQILFADKKNPGVIFTSPVSGKVVEINRGAKRVLQSVVIAVEGEEQVTFNSYAANQLASLDRDAIKQQLIDSGAWTALRTRPFSKVPAIDSETKAIFVTAMDTNPLAADAEVIINQQEDAFVAGLDLLSVLTGEKVYVCKKGGSLPRSSQGNVEEHVFDGPHPAGLAGTHMHYLYPVDLNNVAWSIGYQDVIAFGQLFLTGEIYSDRIVSLAGPAVNNPRLVRTITGASLLELTDSEVMPGEVRIISGSVLNGTQASGPHAYLGPYHQQVCVLREGREKEFLGWAVPGKNKFSVTRSFLSHVFSGQLFNMTTTTNGSDRAMVPIGSYERVMPLDMEPTMLLRDLCAGDVDSAARLGALELDEDDLGLCTYVCPGKYEYGPMLREILDTIEKEG
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit A, Na(+)-NQR subunit A, Na(+)-translocating NQR subunit A, NQR complex subunit A, NQR-1 subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrA family.
Protein: RL3_BORAP
Sequence: MLGLIGKKVGMTQIFQKNGIVVPVTVIEFQPNYIIGKKTVDRDGYSALIAGSVDLKGSKVSKPIKGQYKSLKDIEPKKYVIELKGLDGYDAGDEIKVDVFKSVKYVDVTGTTKGKGFQGAMKRHNFSGGPSSHGSKFHRHLGGTGQATTPARTFKGTKMAGRMGGNQQTIQNLEVVLINEEKRAILVKGAVPGAKGSFVVVKKSKK
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: ATPB_STRA1
Sequence: MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKNGDKSQKVVLEVALELGDGLVRTIAMESTDGLTRGLEVLDTGRAISVPVGKDTLGRVFNVLGDAIDLEEPFAEDAERQPIHKKAPSFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQMGIYPAVDPLASSSRALTPEIVGDEHYEVATEVQRVLQRYRELQDIIAILGMDELSDEEKTLVGRARRIQFFLSQNFNVAETFTGQPGSYVPVEETVRGFKEILDGKHDQIPEDAFRMVGGIEDVIAKAEKMNY
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The catalytic sites are hosted primarily by the beta subunits.
What are the official names of this protein?
ATP synthase subunit beta, ATP synthase F1 sector subunit beta, F-ATPase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: CWC2_CANGA
Sequence: MDSDKGWRQRKARVQLAEVSGELAAAQQTHSVNIWYGKWQSSRHVSVHRLDPERDSGVTRGDSSGTWKFCLYFARGLCALGHKCEYLHHIPEQSDFDRYLVEGTPLLDCFGREKHAENREDMAGVGSFNQQNRTLYVGNIGNAAVMKNGKPLNSRQVESRIRYMFGRLGPMDRVRYLPEKNCAFVRYRHHITAEFAKEAMRDQSLSLSMAQDAALGAQDSTGLLVKWAREDPDPQSRAHKEEDLVNALLSLLPPQQTQTPSRTTSRTTNKTTNEATSKVRKLHRKVYRTTTAAMSHKNILTSYDSD
What is the function of this protein?
Involved in the first step of pre-mRNA splicing.  Required for cell growth and cell cycle control.  Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex.  May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA.  Associates predominantly with U6 snRNAs in assembled active spliceosomes.  Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC2.
What is the protein family that this protein belongs to?
Belongs to the RRM CWC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: PAPA1_MYCTA
Sequence: MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAARGLDHSRLLIASVEVFGHCDLRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPADIEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRADSFTFYASIDHLHADGQFVGVGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINNGTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHELTGADTYFGITPKDIRTPADLMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLAKVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKLFEGLNVGTYSDGRVTYPLSTMVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNNIERMTWRSCRAGDFIDICNLKVANVTVDREA
What is the function of this protein?
Catalyzes the acylation of trehalose-2-sulfate-2'-palmitate (SL659) by adding the (hydroxy)phthioceranoyl group at the 3'-position to yield the diacylated intermediate 2-palmitoyl-3-(C43)-phthioceranyl-alpha, alpha'-D-trehalose-2'-sulfate (SL1278).
What are the official names of this protein?
2'-acyl-2-O-sulfo-trehalose (hydroxy)phthioceranyltransferase PapA1, Polyketide synthase-associated protein A1, SL659 acyltransferase PapA1.
What is the protein family that this protein belongs to?
Belongs to the PapA acyltransferase family.
Protein: COAD_XANCB
Sequence: MSVANSRIAVYPGTFDPITNGHIDLVNRAAPLFERVVVGVAYSPSKGPALPLERRVELAQEALAAHANVEVRGFDTLLAHFVRDMGAGVLLRGLRAVSDFEYEFQMASMNRHLIPEVETLFLTPAEQYSFISSSLVREIARLGGDVSGFVPASVVDALRQVRESRAQV
What is the function of this protein?
Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.
What are the official names of this protein?
Phosphopantetheine adenylyltransferase, Dephospho-CoA pyrophosphorylase, Pantetheine-phosphate adenylyltransferase, PPAT.
What is the protein family that this protein belongs to?
Belongs to the bacterial CoaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATOSB_HUMAN
Sequence: MRHVQAEPSPSSEPEAGPSQPPVRQGALQGGLLMGYSPAGGATSPGVYQVSIFSPPAGTSEPHRALKRQAPSTEGPRELKRGPGLGAREGLPPEEPSTVGLLGPEGPGLGLGVASQHFSHRGLCVVEQRSSVTSSWTSGAWSPPCPPSNASCNTLHTRDWASPDPGGQGSLGESPGPAPPGQLHTLDTDLHSLAQIGGKSPVAGVGNGGSLWPRESPGTANGHSPEHTPPGPGPPGPCPTKRRLLPAGEAPDVSSEEEGPAPRRRRGSLGHPTAANSSDAKATPFWSHLLPGPKEPVLDPTDCGPMGRRLKGARRLKLSPLRSLRKGPGLLSPPSASPVPTPAVSRTLLGNFEESLLRGRFAPSGHIEGFTAEIGASGSYCPQHVTLPVTVTFFDVSEQNAPAPFLGIVDLNPLGRKGYSVPKVGTVQVTLFNPNQTVVKMFLVTFDFSDMPAAHMTFLRHRLFLVPVGEEGNANPTHRLLCYLLHLRFRSSRSGRLSLHGDIRLLFSRRSLELDTGLPYELQAVTEAPHNPRYSPLP
What is the function of this protein?
Transcription regulator that may syncronize transcriptional and translational programs.
What are the official names of this protein?
Atos homolog protein B.
What is the protein family that this protein belongs to?
Belongs to the ATOS family.
Protein: ALKL1_MOUSE
Sequence: MWLTKPSTPVSALLLLALALSPPGTQGRPQRSLAARVAELRPELFLPVTGTRLPPRASRSTEIFPRDLTLKDKFIKHFTGPVTFSAECSKHFHRLYHNTRDCSTPAYYKRCARLLTRLAVSPLCSQT
What is the function of this protein?
Cytokine that acts as a physiological ligand for receptor tyrosine kinase LTK, leading to its activation.  Monomeric ALKAL1 binds to LTK, leading to LTK homodimerization and activation.  In contrast to ALKAL2, does not act as a potent physiological ligand for ALK.
What are the official names of this protein?
ALK and LTK ligand 1, Augmentor beta, AUG-beta.
What is the protein family that this protein belongs to?
Belongs to the ALKAL family.
What are the subcellular locations of this protein?
Secreted. Cell membrane. Note=Following interaction with receptor tyrosine kinase LTK, associates with the cell membrane, membrane-binding is required to activate LTK.
Protein: TRMFO_BRUME
Sequence: MSNNTDLSPVHVIGGGLAGSEAAWQIAQAGVPVVLHEMRPVRGTDAHKTEQLAELVCSNSFRSDDAETNAVGVLHAEMRLAGSLIMACADAHQVPAGGALAVDREGFSQAVTARLEAHPLITIEREEITGLPPTEWGTTIIATGPLTAPSLAEAIAAETDADALAFFDAIAPIIHFDSINMDVCWFQSRYDKVGPGGTGKDYINCPMDKEQYEAFVAALIEGDKTDFKEWEGTPYFDGCLPIEVMAERGPETLRHGPMKPMGLTNAHNPTVKPYAVVQLRQDNALGTLYNMVGFQTKLKYGSQTGIFKMIPGLENAEFARLGGLHRNTYLNSPVLLDNVLRLKSRQTLRFAGQVTGCEGYVESSAIGLLAGRFTAAEKLSQAAVPPPPTTAFGALLGHITGGHIVTDDEPGKRSFQPMNVNFGLFPPVDVPKPEGKRLRGKEKTIAKKRALSARALADCRNWLSLY
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GT031_HIS1I
Sequence: MSGRDISVAIQYPGSRVNRITYPLSKTNIEYEVSADNPFDFDIVLLDCPGLNVLKPLAKAKFSSVPVVYRVQGDVLRAFQEMNYTNFKYRSAKYLFSHLDGAIPIEPVLGRRFSNVTGVRNIGTATLAKSEKYWPNAKHWDESLRLISVTNVNYIGKVQPMVDYAPYISRFLQRNGGHWNIYGKGRLAGYLQDNLGGYDNISYCGYAEDIKSRYANSNCMLHLSNFDSLPNAILEGFASNLPVITNPFSVFSDYHGPIEVTELKKIDAKLCSMQDPTTRRIKARQGQEYLKAKHTPEIVGEQYSVVFRSVLNDC
What are the official names of this protein?
Putative glycosyltransferase ORF31.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family.
Protein: Y1367_PSYIN
Sequence: MPLVFFARVADVSLGTFRTIVIFRGHKFLASFIGFFEIIIWLVASAQVLTNLDQWYLALAYASGFSVGNYAGISIENRFAIGNELIRCISFNRDVLAGKLREEGFKVVSFDGDMGEAYPVELLLVIEKRRNVPSLIQLIKDLDPTAVYSVSDVKSVYEGPDIFPRRSLLHSTLMLLGKR
What are the official names of this protein?
UPF0316 protein Ping_1367.
What is the protein family that this protein belongs to?
Belongs to the UPF0316 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MNMA_XANP2
Sequence: MTDLPLLDTDGDPASTRVVVAMSGGVDSSVVAGLYARAGYDVVGVTLQLYDHGEAAHRRGACCAGQDIYDASEVARTLGIPHYVLDYESRFKEEVIDRFAASYASGVTPIPCVDCNRTVKFRDLLATAEELGARYLATGHYVASRALPDGRRGLYRAAEEARDQSYFLYATTAAQLERLRFPLGEMRKADVRALAAEFGLPVADKPDSQDICFVPGGDYAQVVQRLRPEAAEPGDIVHLDGRVLGRHRGVMHYTIGQRKGLGIATPEPLYVIAIDAARQQVRVGPRAALSVSAITIDDVNWLGDIPFTDALARQADVYVKVRSTRPPVPAHLARATDGTPAVHLAVGEEGVAPGQACVLYDDAGAAARLLGGGTIMRAERVAKSVAEVA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BPC7_ARATH
Sequence: MNSFPAQNLMLSATNANKDSGLRTSNAHWLHSCIAVPKTTGIDLSQEPPAEGVMVPQSHLFPPPIRDSRNDTETVKQKSVNQSPSKALKPKPQRKKRSVSNKSKKTPSIPETKREKKNLDINIDISSFDTSGVPPPVCSCTGVSRVCYKWGMGGWQSSCCTISISTYPLPMSTTRPGARLAGRKMSNGAYVKLLARLADEGYDLSHPLDLKNHWARHGTNKFVTIK
What is the function of this protein?
Transcriptional regulator that specifically binds to GA-rich elements (GAGA-repeats) present in regulatory sequences of genes involved in developmental processes.
What are the official names of this protein?
Protein BASIC PENTACYSTEINE7, AtBPC7, GAGA-binding transcriptional activator BBR/BPC7.
What is the protein family that this protein belongs to?
Belongs to the BBR/BPC family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ZFP36_ORYSJ
Sequence: MTAALQALLDPTALSLGLPTPAINKEEYLAICLAALACTRAGKALVGVGGQQQVQACNKWLCPAPAAPEELRFRCTVCGKAFASYQALGGHKSSHRKPPSPGDHYGAAAAAQQLASAGDSKEDSASSAAGSTGPHRCTICRRSFATGQALGGHKRCHYWDGTSVSVSVSASASAASSAVRNFDLNLMPLPESTAAAGIKRWAEEEEVQSPLPVKKLRMSN
What is the function of this protein?
Probable transcription factor involved in abscisic acid (ABA) signaling.  Required for the regulation of the cross-talk between NADPH oxidase, hydrogen peroxide and MAP kinase in ABA signaling.  Regulates the expression of the NADPH oxidase genes RBOHB and RBOHE, and the MAPK genes MPK1, MPK4, MPK5, MPK7 and MPK14.  Regulates ABA-induced hydrogen peroxide production and antioxidant defense.  Required for tolerance to water stress and oxidative stress.
What are the official names of this protein?
Zinc finger protein 36, Protein BROAD-SPECTRUM RESISTANCE DIGU 1.
Protein: CSRA_BUCCC
Sequence: MLILTRRIGETLIIGDEITVTLLGIKGNQIRVGINAPKKISVHREEIYKKIQLEKKNLL
What is the function of this protein?
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability.  Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems.  Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA.  Its function is antagonized by small RNA(s).
What are the official names of this protein?
Translational regulator CsrA, Carbon storage regulator.
What is the protein family that this protein belongs to?
Belongs to the CsrA/RsmA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y244_THEP1
Sequence: MKKIKSFGGKNLGGGKQEKLLKDFAKMQEELQKKIQELEESFSQIEVEASVGGGAVRIVATCDRRVKDIEIDEDLKEDFDTLKDLLIAGMNEVMEKIEKRREEEMSKITQQFGIPGLM
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein Tpet_0244.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: YA72_SCHPO
Sequence: MWSFARYTQKFCLRNLQLKNFSNKVKVSSLLFCSPNVRNISNWQCKRFTQSDAKDLASGVPSVKSDADQLQPKPTYNVSFTCTVCNTRSNHNFSKQAYHNGTVLVQCPKCKNRHLMADHLKIFSEERVTIEDILAKKGETFKKGYGQVINGNVVEFKPPQFKIRPAKSSSSNSSK
What are the official names of this protein?
Uncharacterized protein C24H6.02c.
Protein: RL2_RICFE
Sequence: MALKNFNPITPSLRELVQVDKTSLWKGRPLKSLTKGISKTGGRNNQGRITSWHRGGGHKKLYRIIDFKRNKIDISAIVERIEYDPNRTAFIALIKYEDGEYSYILAPQKLSVGDRVISSQDADIKIGNCLPLKFIPTGTTLHNVEMKVGKGGQIARSAGTSVDLVGKDSGYAQIKLRSGEFRLVPLDCKATIGSISNPDQKNINLGKAGRNRWLGWRPHVRGVAMNPVDHPHGGGEGKTSGGRHPVTPWGFPTKGKKTRKNKRTSKFIVKKRK
What is the function of this protein?
One of the primary rRNA binding proteins.  Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation.  It has been suggested to have peptidyltransferase activity; this is somewhat controversial.  Makes several contacts with the 16S rRNA in the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L2.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL2 family.
Protein: SYK_COXB2
Sequence: MELKDQIKEENEQIAQRKLKLKKRREEGQAYPNDFKRDSLAADLHAVYDQFDSGALTAKAIRVKMAGRMMTRRIMGKASFAHIQDMKGRMQIYVTRDSLPQGVYSDFKSWDLGDIVGIEGELFKTKTEELSVKVDQIRLLTKALRPMPDKFHGLHDQEQRFRQRYLDLIVNESSRHLFQTRSQVIAQIRRFLDDRGYIEVETPMMHPLPGGAAARPFETHHNAMNMDLFLRIAPELYLKRLVVGGFEKVYEINRNFRNEGISTRHNPEFTMLEFYQAYATYEDMMMLTESMIRHLAEKIFGVMEIKYQGVRIDLNKPFPRLSLRDAILQFNPGITPDQIDHLETARELAHKYEIATPAHYGLGKIQTELFEKLVEEKLQQPIFITHFPKEVSPLSRANEENDFITDRFEFYVGGREIANGFSELNDPEDQAARFREQLKARNAGDLEAMSFDEDYITALEYGLPPTAGEGIGIDRLVMLFTDNASIRDVILFPLLRSK
What are the official names of this protein?
Lysine--tRNA ligase, Lysyl-tRNA synthetase, LysRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IDHC_SOLTU
Sequence: MAFQKITVQNPIVEMDGDEMTRVIWKSIKDKLILPFLELDIKYFSLGLPHRDATDDKVTVESAEATQKYNVAIKCATITPDEARVKEFNLKSMWRSPNGTIRNILNGTVFREPIMCKNIPRLVPGWTKPICIGRHAFGDQYRATDTVIKGAGKLKLVFVPEGSDEKTEFEVYNFTGAGGVALSMYNTDESVRSFAEASMNMAFQKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKSKYEEAGIWYEHRLIDDMVAYALKSEGGYVWACKNYDGDVQSDFLAQGFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYRVHQKGGETSTNSIASIFAWTRGLAHRATLDNNERLLDFTEKLEAACIGAVESGKMTKDLALIIIHGSKLSREHYLNTEEFIDAVADELKARLLKAKA
What is the function of this protein?
May supply 2-oxoglutarate for amino acid biosynthesis and ammonia assimilation via the glutamine synthetase/glutamate synthase (GS/GOGAT) pathway.
What are the official names of this protein?
Isocitrate dehydrogenase [NADP], IDH, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate and isopropylmalate dehydrogenases family.
What are the subcellular locations of this protein?
Cytoplasm.