PharMolix/UniProtQA huggingface dataset:
Protein: GLAH_ECO45
Sequence: MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTNRFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGIDDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHFFRHPLARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ
What is the function of this protein?
Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG).  Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
What are the official names of this protein?
Glutarate 2-hydroxylase, G-2-H.
What is the protein family that this protein belongs to?
Belongs to the glutarate hydroxylase family.
Protein: NOG1_CAEEL
Sequence: MTSMYNFKRITCVPNAQELKDVVLSKTQRKTPTVVHRQYSIGRIRAFYARKIKFLQQTLHDKLTQIITEFPKMEEIHPFYSDLMNILYDRDHYKIALGQMNTARHLIDGIAREYVRLMKYADSLYRCKMLKRAALGRMVKLLKRQKSSFEYLEQVRQHLSRLPSIDPATRTLILCGFPNVGKSSFINNVTRADVEVQPYAFTTKALYVGHLDYRFLRWQVIDTPGILDQPLEDRNTIEMQAVTALAHLKASVLFMMDVSEQCDRSIEEQLHLFESIRPLFANKPVLIGLNKVDIRHRSDLPPEKAALLDQLEKEGIPIIETSTLTQEGVMGLRDRACDELLAQRVEAKIQAKKITNVEDCVLNRVFVAYPAPRDEKVRAPFVPPGLAAKRAQKKLQEAQELMETDGDEFAAKIPQKPGKIGKEKIAKGGSQSTDLGDLRDENTRRLEREIELEMQDDYILDLKKHYMLKNPDEKYDIVPEIWEGHNLADFVDPEIQSKLENLLREEELLEQAGEYESDLDSDDEETKEKLKLALQIREKEKLLTLDHAVNKRIAGRIGSRIHGSRKRDRSMSRLENELGELGVDVDTKKMKNLQGQCAKPQLGKKMKVGRSRSLSAVRPAPRDELAFPDEEKRAHVDKLRTKAMRGLRREAKKGEADRHVYDLKPKHLFCGKRGNGKTDWR
What is the function of this protein?
Involved in the biogenesis of the 60S ribosomal subunit (By similarity).  Has a role in regulating longevity, growth and brood size (PubMed:24552710).  May regulate fat storage via the insulin/IGF pathway (PubMed:24552710).
What are the official names of this protein?
Nucleolar GTP-binding protein 1.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: SSDH_MOUSE
Sequence: MATCFLLRSFWAARPALPPPGRFRPEPAGTPRRSYASGPGGLHADLLRGDSFVGGRWLPAPATFPVYDPASGAKLGTVADCGVPEARAAVRAAYDAFNSWKGVSVKERSLLLRKWYDLMIQNKDDLAKIITAESGKPLKEAQGEILYSALFLEWFSEEARRIYGDIIYTSAKDKRGLVLKQPVGVAAIITPWNFPSAMITRKVGAALAAGCTVVVKPAEDTPYSALALAQLANQAGIPAGVYNVIPCSRNKAKEVGEVLCTDPLVSKISFTGSTATGKILLHHAANSVKRVSMELGGLAPFIVFDSANVDQAVAGAMASKFRNAGQTCVCSNRFLVQRGIHDSFVTKFAEAMKKSLRVGNGFEEGTTQGPLINEKAVEKVEKQVNDAVAKGATVVTGGKRHQSGGNFFEPTLLSNVTRDMLCITEETFGPLAPVIKFDKEEEAVAIANAAEVGLAGYFYSQDPAQIWRVAEQLEVGMVGVNEGLISSVECPFGGVKQSGLGREGSKYGIDEYLEVKYVCYGGL
What is the function of this protein?
Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
What are the official names of this protein?
Succinate-semialdehyde dehydrogenase, mitochondrial, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: TRM82_YARLI
Sequence: MKHPYHIVSLSPDGKTMYAAAARQVDRICLETGECKSTVVEESATRTTTKTGDKPAAAKRTKYLPTSVSHVRSLQLSKGGKYLLATTDETKSLVLLDPTTLEVIKKVQYPKRPSAVATDKEDLNIVLGDKFGDVYGESVEDLLKVEGELKDEPVLGHVSMLTALELGYDSKDRPYVISADRDEHIRISRFPASHVIEQFCFGHQQFVSSLLINDLDASILFSAGGDDEIFVWDWLNGKQLQKLSLREHVESYLNEAHIYVDKKGVATTHKEITVSSLQQIKDTPYLLVNVESTNAIIVLKIVDNKLEVASVFATEAHVISFSVAGNLLVTSEVGSEGVKAYTITDGVVTKSDKEIPFGSCEYEDDSELISLFSTKSLRKRGEF
What is the function of this protein?
Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.  In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.
What are the official names of this protein?
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82, Transfer RNA methyltransferase 82.
What is the protein family that this protein belongs to?
Belongs to the WD repeat TRM82 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: SF3A2_DICDI
Sequence: MSEYGKAGSGGLQSSQYDNIDRRERQKQLVLEHVDVSKDPYIISNHIGSFECRLCLTVHNNVGNYLAHTQGKKHQTHLARRAAKEQRENPSVSKNNYIQTTRVIHKKTIKIGRPGYKIIKQRDSKTGQLSLLFQIDYPEIESGLQPRHRIMSAFEQRVEQPNKDYQYLLFAAEPYETIAFKIPNKEIDRTTGPDGKFFTHWDRNKTFTLQLYFKE
What is the function of this protein?
Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex.  Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex.
What are the official names of this protein?
Splicing factor 3A subunit 2.
What is the protein family that this protein belongs to?
Belongs to the SF3A2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ARGC_PROM2
Sequence: MNVAIVGATGYGGIQAVNLLKKNKNYKISFLGGNKTSGSKWNDNFPFIYLDNDPYVEEISVDNISKNSDVALLCLPNGLSSTLTRKLLERGLKVIDLSADYRYKSLDEWKKVYSKEAAIYKRNDDDLCKEAVYGLPEINKEAISKGRLIACPGCYPTSALIPLAPYLSQGIIENEGIVIDSKSGTSGGGREPNQKLLLSECGEGLSAYGLINHRHTSEIEQVASLISGNKIELLFTPHLVPIPRGMHSTIYGRLRDPGLTSDDCRILLDNYYRNFKNIKVLPVDTFPSTKWVKNTNQIFLSVKVDIRNGRIIILSAIDNLLKGQTGQAIQNLNIMSGFSMDEGLELTNNYP
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
What are the official names of this protein?
N-acetyl-gamma-glutamyl-phosphate reductase, AGPR, N-acetyl-glutamate semialdehyde dehydrogenase, NAGSA dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR7_PINTH
Sequence: MSRRSTAEKKTAKSDPIYHNRLVNMVVNRILKNGKKSLAYRILYRAIKKIQQKTDKNPLSVLRQAIRRVTPNVTVKARRVGGSTYRVPTEIRSTQGKVLAIRWLLGASRKRPGRNMNFKLSHELMDAARGNGNAIRKKEETHRMAEANRAFAHFR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.
What are the official names of this protein?
30S ribosomal protein S7, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: USF2_MOUSE
Sequence: MDMLDPGLDPASSATAAAAASHDKGPEAEEGVELQEGGDGPGAEEQTAVAIASVQQAAFGDHNIQYQFRTESNGGQVTYRVVQVTDGQLDGQGDAAGAVSVVSTAAFAGGQQAVTQVGVDGAAQRPGPAAASVPTGPAAPFPLAVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQTGTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCHADNSKTGASKGGILSKACDYIRELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQQHNLEMVGESTRQ
What is the function of this protein?
Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.
What are the official names of this protein?
Upstream stimulatory factor 2, Major late transcription factor 2, Upstream transcription factor 2.
What are the subcellular locations of this protein?
Nucleus.
Protein: LUXS_CAMJ8
Sequence: MPLLDSFKVDHTKMPAPAVRLAKVMKTPKGDDISVFDLRFCIPNKDIMSEKGTHTLEHLFAGFMRDHLNSNSVEIIDISPMGCRTGFYMSLIGTPDEKSVAKAWEEAMKDVLSVSDQSKIPELNIYQCGTCAMHSLDEAKQIAQKVLNLGISIMNNKELKLENA
What is the function of this protein?
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment.  The regulation of gene expression in response to changes in cell density is called quorum sensing.  Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).
What are the official names of this protein?
S-ribosylhomocysteine lyase, AI-2 synthesis protein, Autoinducer-2 production protein LuxS.
What is the protein family that this protein belongs to?
Belongs to the LuxS family.
Protein: CA112_DANRE
Sequence: MSQVTLLDEVSQWNQETCQQELKTVLPKLVAMHHDTDSWEEHTNILQIITSRFLPHLSLSDLETGCFSTALPKVVKVFASLLEEISKQIGGLSSQNTELQLFLRKILKTMVQTLECLSGCVRHVCSIEESVSFSNIRSLPSCILGVLKDTFQHCKDSEVMYSGRLSLVGDLLQGLFKEAYSLQKGLMELLDKINFEDTASEEEISDIVTVIHSLLDICLIISRLDIALHANTWKFIIKQSIKYQSLVEDRLHHTDISFALCEDLCRSVENCLELAQQIQQAGLQEAVHSPEYKLFQKATKMCRFFANTLVHYTKEFKVFLSKSCSRFHQLYLQINSKFLPSLCAPSVPPTLSEELRVAVLVPMDAMLTQMMSFQPFAESVLNPDHQSSAKLFLPQCLLLVNVMGKLSSQPEEALRLWSDGSQFPEETPRWSVFEAVFQSFRLCVLERLVPVCLPGVMLRGQAQGTVSLHQHVCVHMCACVAVLPAQHFPPLERSLLAAVLQADTQTALLATDVWCFLARYGTAELCYHHVVLIAHLLRACPAGGYQLFHLALVLRRLLFLMTPKHQVEFVERFPLSQEENLCVWRHTLLKCLCVEARVRVEEQVLDRATVVLEEWQNSGCRLGEIPRLNRILDCVLLVVGGSGTQNECVESLVKIISQLWSHMRSSQVQVHVTLQCTVKLLLSLSAVLIKSLEPHIILQAVSCLSGLSIHQCPDDLLLAALEFLASLGQIFIPPNIQGQVLPQISSLFNGFLTRPSWLILHHVLEAFGCFAEITNHEEVISQTLKTEEVKSKVLNFLSKTVSRQESEETRLERLKEWKCVIEKHCQQMESEKSQPAQTPLTEEPCAKRARQETKAEEEYERYLQTAEGALKALQAIERSEHSPSPPQWVRARLQLLQTLITQINTTTEEQS
What are the official names of this protein?
Uncharacterized protein C1orf112 homolog.
Protein: NDHH_MESVI
Sequence: MLQTKTDPMVISMGPHHPSMHGVLRLIVTLDGENVIDCEPVLGYLHRAMEKIAENRTIVQYLPYVTRWDYLATMFTEAITVNAPEKLANIEVPKRASYIRVIMLELSRIASHLLWLGPFMADIGAQTPFFYILREREMIYDLFEAATGMRMMHNYFRIGGVASDLPYGWVDKCLDFSDYFLPKVDEYERLITNNPIFLKRVRDVGFISREEAINWGLSGPMLRASGVQWDLRKVDNYECYGELDWNVQWQSDGDCLARYLVRLGEMRESTKIIQQALKAIPGGPYENLEARRLSKGRKSEWNNFEYQFVGKKPSPTFKIPKQEHYVRVEAPKGELGVFLMGDDNVFPWRWKIRSPGFINVQILPELVRGMKLADIMTILGSIDIIMGEVDR
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic, NAD(P)H dehydrogenase subunit H, NADH-plastoquinone oxidoreductase 49 kDa subunit, NADH-plastoquinone oxidoreductase subunit H.
What is the protein family that this protein belongs to?
Belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side.
Protein: PROB_HAEIG
Sequence: MNKKTIVVKFGTSTLTQGSPKLNSPHMMEIVRQIAQLHNDGFRIVIVTSGAIAAGRHYLNHPQLPPTIASKQLLAAVGQSQLIQAWEKLFAIYDIHIGQLLLTRADIEDRERFLNARDTLHALLDNHIIPVINENDAVATAEIKVGDNDNLSALVAILVQAEQLYLLTDQQGLFDSDPRKNSEAKLIPVVEQITDHIRSIAGGSGTNLGTGGMMTKIIAADVATRSGIETIIAPGNRPNVIADLAYEQNIGTKFIAHQSDRLESRKQWLFAAPSAGIITIDNGAQNAILEQNKSLLPAGIINVEGRFSRGEVVKIRTQSGKDIALGMPRYNSDSLQLIKGRKSADIENVLGYEYGAVAMHRDDMIILS
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HINT3_BOVIN
Sequence: MMEEEECGLGKSCARSEPVAAAQPAGSPGETPAVAAESPELANYSSKCVFCRIAAHQDPGTELLHCENEDLVCFKDIKPAAPHHYLVVPKKHFENCKYLKKDQIELIENMVTVGKAILERNNFTDFENTRMGFHVSPFCSIAHLHLHVLAPADQLSFMSRLVYRVNSYWFITADYLIEKLRT
What is the function of this protein?
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (By similarity).  Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase (By similarity).
What are the official names of this protein?
Adenosine 5'-monophosphoramidase HINT3, HINT-4, Histidine triad nucleotide-binding protein 3, HINT-3.
What is the protein family that this protein belongs to?
Belongs to the HINT family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: PDXT_SULIL
Sequence: MKIGIIAYQGSFEEHYLQLKRAFDKWSINGEITPVKIPKDLKDIDGVIIPGGESTTIGLVAKRLGILDELKEKITSGLPVMGTCAGAIMLAKEVSDAKVGKTSQPLIGTMNISIIRNYYGRQRESFETIIDLSKIGKGKANVVFIRAPAITKLWGKAQSLAELNGVTVLAEENNILATTFHPELSDTTSIHEYFLHLVKG
What is the function of this protein?
Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate.  The resulting ammonia molecule is channeled to the active site of PdxS.
What are the official names of this protein?
Pyridoxal 5'-phosphate synthase subunit PdxT, Pdx2, Pyridoxal 5'-phosphate synthase glutaminase subunit.
What is the protein family that this protein belongs to?
Belongs to the glutaminase PdxT/SNO family.
Protein: UNG_ERWT9
Sequence: MVNTMTWHDVLAEEKEKPYFRNTLARVAAERAAGKTVYPPQTDVFNAFRLTELGGVKVVILGQDPYHGPNQAHGLAFSVLPGVPVPPSLVNMYKELVTDIPGFERPNHGFLESWARQGVMLLNTVLTVEAGQAHSHVKFGWETFTDNVIAAINQHREGVVFLLWGAHAQKKGSIIDRKRHHVLHAPHPSPLSAHRGFFGSAHFSQANRWLTEHGESAIDWMPQLPAR
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPH2_BRADU
Sequence: MEVYLAQPRGFCAGVVRAIEIVERALEKFGPPVYVRHEIVHNKYVVESLKNKGAIFVEELSEVPPKAVTVFSAHGVARSVEEEAAARDLPVLNATCPLVTKVHNQGKRYITKGRTLILIGHAGHPEVEGTMGQVPAPVLLVQSVEEVNALTLPADTPVAYITQTTLSVDDTRDIISALQARFTDIQGPDIRDICYATQNRQSAVRDLSKLVDVILVVGAANSSNSNRLREIGTEAGVASYLIADGSELNPEWLKDARTVGVTAGASAPEVLVDDVIEAMRRIGPVKVQVLPGREENIEFRLPAELAAS
What is the function of this protein?
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP).  Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.
What are the official names of this protein?
4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2, HMBPP reductase 2.
What is the protein family that this protein belongs to?
Belongs to the IspH family.
Protein: SYT_BDEBA
Sequence: MLMSQITIILPDNSTKVFDHEPTALEVAMSIGPRLAKETLGAKLNGSTEISDLRTVLKDQTKVALVTTKSPESVEVVRHSCAHIMAQAIQDIWPEVKVTIGPVIDNGFYYDFDSPFAFTEEHFEKIEKKMSEIVSKDLPIHREDWPIQKAIETFKGMNERFKVELIEDLAKKGETTVGIYFNGTSWFDLCRGPHIQSTGQIKAFKLLSVAGAYWRGDEKNAQLQRVYATAFNDKKDLETYLHNIEEAKKRDHRKLGKELGMFYFNELAPGSPFFTGKGATVYNSLQTYLRELYFETGYQEVITPQIFDVNLFHTSGHYQNYKENMFFTKVDERDFASKPMNCPSHCLLYNSEKYSYRDLPIKMADFGRLHRYEKSGAMHGLTRVRTFCQDDAHIFCRMDQLQEEIAKFMNLLNRVYDKLGMGNYKIFLSTRPDNRMGSEEYWDMAEGALAEALKSLNLPFELNPGDGAFYGPKLDIMFVDALNRPWQLGTLQVDPNLPQAFDLKYTGEDNKEHRPVMLHRAILGSLERFIGVYLEHTAGHLPPWMMPVQVAILNVTDRVNSFCEELQNSLKGHSVRVEFDRRNEKLNYKIREAQLQKIPYMIIVGDKEAESRTVSLRLRDGSEHKGLTVDQVMNLITTDIKTRSLQSSLAKSATTN
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YIPF3_XENLA
Sequence: MANSSGSSRNLTAADWGGFDDNMQSGGGAAVIDMENMDDTSGSSFEDMGEIHQHMKEEEEEVEGEGVPEDGEEDGAFLGMKGVQGQLGRQVADEMWQAGKRQASKAFNLYANIDILRPYFDVEPIQVRHRLLESMIPVKMISFPQKIAGELYGPLMLVFTMVAILLHGMKSSGTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQTLSLLGYGLFGHCIVLFITYNIHFHSLFYIFWLCIGGLSTLRMVAVLLSRTVGHTQRLIVCGTMAALHMLFLLYLHFAYHKVVEGILDTLDGQNVPLPIQRVARDLPVGPNTVLNATVQVLLAHSR
What is the function of this protein?
Involved in the maintenance of the Golgi structure.  May play a role in hematopoiesis (By similarity).
What are the official names of this protein?
Protein YIPF3, YIP1 family member 3.
What is the protein family that this protein belongs to?
Belongs to the YIP1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Cytoplasm.
Protein: RS7_UREU1
Sequence: MRKLKPQKRQVLADPVYNSRLVTKLINAIMYDGKKGLAQSIIYSAFEIVEQKTGKPALEVFNKAIDNVMPIIELKVRRVGGSNFQVPTEVTPERRQTLGLRWITLYARLRHEHTMIEKLAHEIIDASNNVGAAIKKKEDTHKMAEANKAFAHLRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: WASH1_DICDI
Sequence: MTTQIYQVPVVSNGLRETESILQIVDSLEKLEKVFNDMYSTISARVSHEKSRIDNVANRLNNAQHKVNQIVGSKQAITVFSSAKYPADKKWGDYVPIYSGKHKLPFKPSHYHGLNSEDSPIKKRPEDSYLDVNDLVFIEKSIDTTSKEVEVKEGLGRIPAQIPSVSNLLLFNTQENPYKKYSNTLDNLSGGDGGEDDYTIFGDQLSKKKRLGDAPVTVKDGDSRIDAENVKIGYEPGTFEIPVYNFPSILPLPNVAENITWAAESQSIAPSQKATLNLLPTYDNSNSGSAPVNQSSGGDNNVNNNNNNNNSNNSTGIMQPPQPTNAPPPPPPPPQSANAPPPPPPPPVSAPPPFNPPSVNSNNDDDDDDDDDNGGGGGPGGAIGDLLADIRRGHKNRLKKADVGGDNGDGEDNKPPPVSDGGGGLMGDLFKKLALRRQSIATTKSTKKQSKSKKEDTDDQDGESDTDSSEWE
What is the function of this protein?
Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization.
What are the official names of this protein?
WAS protein family homolog DDB_G0292878.
What is the protein family that this protein belongs to?
Belongs to the WASH1 family.
Protein: E248R_ASFM2
Sequence: MGGSTSKYSFKNTTNIISHSIFNQMQNCISMLDGKNYIGVFGDGNIINHVFQDLNLSLNTSCVQKHVNEENFITNLSNQITQNLKDQEVALTQWMDAGHHDQKTDIEENIKVNLKTTLIQNCVSALSGMNVLVVKGNGNIVENATQKQSQQIISNCLQGSKQAIDTTTGITNTVNQYSHYTSKNFFDFIADAISAVFKNIMVAAVVIVLIIVGFIAVFYFLHSRTAMRRRKKLNRS
What is the function of this protein?
Essential for viral fusion with host endosomal membrane and core release.
What are the official names of this protein?
Inner membrane protein pE248R, pE248R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus E248R family.
What are the subcellular locations of this protein?
Host membrane; Single-pass type II membrane protein. Virion membrane. Note=Probably part of the virion inner membrane.
Protein: AGLU_SPIOL
Sequence: MKKKIPSLALGILLVFLLQYLVAGISTSENDPEGVIGYGYKVKSVKVDSGTRRSLTALPQLVKNSSVYGPDIQLLSITASLESNDRLRVRITDAKHRRWEIPDNILHRHQPPPPPPHSLSSLYRTLLSSPTTNRRKILLSHPNSDLTFSLINTTPFGFTISRKSTHDVLFDATPDPTNPNTFLIFIDQYLHLTSSLPGTRAHIYGLGEHSKPTFQLAHNQTLTMRAADIPSSNPDVNLYGSHPFYMDVRSSPVAGSTHGVLLLNSNGMDVEYTGNRITYKVIGGIIDLYFFAGPSPGQVVEQFTRVIGRPAPMPYWAFGFQQCRYGYHDVYELQSVVAGYAKAKIPLEVMWTDIDYMDAYKDFTLDPVNFPLDKMKKFVNNLHKNGQKYVVILDPGISTNKTYETYIRGMKHDVFLKRNGKPYLGSVWPGPVYFPDFLKPSALTFWTDEIKRFLNLLPVDGLWIDMNEISNFISSPPIPGSTLDNPPYKINNSGVMLPIINKTIPPTAMHYGDIPEYNVHNLFGYLEARVTRAALIKLTEKRPFVLSRSTFSGSGKYTAHWTGDNAATWNDLVYSIPSMLDFGLFGIPMVGADICGFLGNTTEELCRRWIQLGAFYPFSRDHSSLGTTYQELYRWESVAASARKVLGLRYTLLPYFYTLMYEAQLNGIPIARPLFFSFPDDIKTYGISSQFLLGKGVMVSPVLKPGVVSVTAYFPRGNWFDLFDYTRSVTASTGRYVTLSAPPDHINVHIQEGNILAMQGKAMTTQAARKTPFHLLVVMSDCGASFGELFLDDGVEVTMGVNRGKWTFVKFIAASAKQTCIITSDVVSGEFAVSQKWVIDKVTILGLRKGTKINGYTVRTGAVTRKGDKSKLKSTPDRKGEFIVAEISGLNLLLGREFKLVLH
What is the function of this protein?
Alpha-glucosidase I and II have high activity towards malto-oligosaccharides and starch, while form III and IV have high activity towards malto-oligosaccharides but low activity toward starch.
What are the official names of this protein?
Alpha-glucosidase, Maltase.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 31 family.
Protein: UTP10_KLULA
Sequence: MSSLRDQLAQVAQNNATVALDRKRRQKLHSASLVYNPKTAATQDYEYIYDTALESFHTLVSLDLRFKVFTNSLFSASSVTIDRNVQTKDQIRDLDNAVNAYLMLISPKWHLTPALHATEWLIRRFQIHIHNAEMLLLSTLNQYQTPVFKRILNIVKLPPLFNPFTNFVRNDKNPTDLTLIKLFNDMDFLKLYSNYLSKIIKQKVTYTNQLLFTTCCFINVIAFNANDEDKLNKLVPLILEISAKLLASDSSDCQMAAHTMLAVLATALPLNKSIIIAATETILANLKEDDARKKALVTISKLFQTLKGVGNVDQLPVKIYKLVDNSFPFEYLLQFLSNENKYSSDKFFTAYIRSVIRYDHDKLSQIVKILRKIKLEKYEVRFIITDLIHLSEVLEDKSQLIDVFEYFISINEGLVLKCLQALNLTGEVFEIRLTTSLFSVKNSAEQSGEDIIKVLDDAKASTANGSAVPFKDFMTKNSEFISTKAESMLLVKDEKFVKLLSLFVEAVSKGYQPGLFLSSFFTTLESRITFVLRIIVSPGSPVALRLISLTQLSKFINGIDEQTDLFSLVPILVTALMDISRSVRSNTKKVLQQIAKRPFTAKYFLSNVLYGENLKVPMLSPKDSKFWLTNFLSDYIVESTDISSLVIPSKNDMVYMLFWCNQALHLPLAYSKTIMLKLLTAVPQYAFTYSKVFEQFMATYITERSSWETKCIKNKTNFKDFETAVCAIVAPKEKNSFAIDFLINCLESEYEQLSNIMADRILSLYPTLKFPNQLKIVQSIIDSSVDKELSYDGLETLQSLPLTADIFVSVLKSNTINSEDQTDLTKRRRRRSSTVNKSALQKQDISQIAEAHLKKMTIILETLDKLKVKSNENLLNALFNLLSDLETLDHDGGLPVLYAQETLSSCLLNTISSLKSNNGSMKLPSIRADILVAAIRSSTSPQMQNKLLLVVGALASVSPETILHSVMPIFTFMGAHTIRQDDEFSTLVVERTISTIVPALLKSTEVTNKSDEIEFLLMSFSTAFSHVPKHRRVSLYSTLVRELGPSDVIAPFLFLIAQQYSNCLEKFKIAESKNYIEFFKAFLSKFDILEQLHGFNELFNLVELLDEDSSKNEVAPTRTLFSNGIVNMSKSELFVLKKNDLDFIDKVIGESKSDYYNTSSNLKLRILSTLLDPNIEIEVKNQVRNEFSILLSKTLNAINMTDSLSYDKHSSAGSNDEEAGSESEAEVDQKELKDILFGLLEHVLDLLPIQDFVASILPLLQGNTDESVRHHLTVVTSNKFIEEPMESFETANEILSTLVETTEKASESTQILQVTLNTISSIVTRFGDRLDSHLLVKSMENSCKQLTSKKIELEISSLTVLTTLIQTLGVKTLAFYPKIVPVAISIFKTYQNAKNNLKEQLQLAIVLLFASMIKKIPSFLLSNLQDVFVILFHSDEVADSVRLSVISLIVEHIPLKDVFKTLQKVWTNDVSSSNNSVAVSLFLSMLESAVEAIDKKSATQQSPVFFRLLLNLFEYRSICTFDENSINRIEASVHQIANVYVLKLNDKVFRPLFALVVNWAFNGEGVTNTNMSKEERLMAFYKFYNKTQENLKSIITSYFTYLLEPTNNLLKQFISKETVNVSLRRLVLISLTSSFKYDRDEYWKSTSRFELISESLINQLTNVEDVIGKYLVKAIGSLATNNSGVDEHNKIMSDLMISHMKTSCKTREKFWAVRSMKLIYSKVGDGWLVLLPRLVPIIAELLEDEDEEVEYEVRSGLVKVVESVMGEPFDRYLS
What is the function of this protein?
Involved in nucleolar processing of pre-18S ribosomal RNA.  Involved in ribosome biosynthesis (By similarity).
What are the official names of this protein?
U3 small nucleolar RNA-associated protein 10.
What is the protein family that this protein belongs to?
Belongs to the HEATR1/UTP10 family.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: TGT_ECO24
Sequence: MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
What is the function of this protein?
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr).  Catalysis occurs through a double-displacement mechanism.  The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate.  The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product.  After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
What are the official names of this protein?
Queuine tRNA-ribosyltransferase, Guanine insertion enzyme, tRNA-guanine transglycosylase.
What is the protein family that this protein belongs to?
Belongs to the queuine tRNA-ribosyltransferase family.