PharMolix/UniProtQA huggingface dataset:
Protein: UGPB_BRUA2
Sequence: MFTRLITTSVLTGAIALTIGSQAFAQTELAWWHGMTGANNEMVNELSKEFNESQSEYKIVPVYKGNYPETLNAGIAAFRSKQPPAILQVFDAGSGVMMAAEGAIVPAAEVLEKGGYKFDKSQYLPGIVAYYSKPDGTMLSFPYNSSSPILYYNKDAFKKAGLDENKPPKTWPEVFEAAKKIKASGASPCGFTSTWLTWIQTENFAAWNNVPYGTNENGLAGTDVKLEINSPLYVEHFQAIADLAKDGTFRYGGRTSEAKQLFTSGECAMLTESSGGLGDVVKSGINYGIGQLPYYEGHGPQNTIPGGASLWVFAGLSDDQYKGIAEFFNFLSQTKIQVKLHEKSGYLPVTLAAYEETKKSDFYEKNPGRETPILQMMGKEPTENSKGVRLVNLPQVRDILNEEFEAMLGGKQDAKTALDNAVKRGNAAIAAAQ
What is the function of this protein?
Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import.  Binds G3P.
What are the official names of this protein?
sn-glycerol-3-phosphate-binding periplasmic protein UgpB.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 1 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: Y3576_BRUSU
Sequence: MLNRFIAFFRSVFLIGLVATAFGALPARAANETAPDYALSMHGDVALPADYTHFPYTNPDAPKKGSLTVGVVGTFDSLNPFVLKSMRTTARGLYNDGEFGNMVYQTLMLRSRDEPFTLYSLLAEKVAIDPERKWVEFTLNPKAKWSDGQPVTVDDVLFTYDILTEKGRPPYNSRMSRVAKIEKTGERSVRFTFNEKSDREFPMLIAGSMPVLPKHAINRDTFGNSTLEPPIGSGPYVVASVQPGQRIVYKRNPDYWGKDLPSQRGFNNFDKISIEYYRNETSLFESFKKGILDIFIEGNPIRWEKLYDFPAVEQGKVIKDTFEKGTPADMLGFVFNTRRPIFADRRVRQALGLLFDFEWANRNLFAGQYRRTQSFWEGSQLSSVGRPADARERELLAAFPGAVREDVMNGTWHPPVTDGSGHDRVPAKKAYDLLSQAGFQFKDGMAIDPTGKPFAFEIMTRSPDEEKIALAYQRNLSRLGIAVEIHTVDDAQYQQRLQTFDYDMILGALASSLSPGNEQWLRWGSASRDVQGSFNFAGVADPAVDAMIEALLAARNRADFVSAVRALDRVLISGDYYVPLYHLPYQWVARWDRIEHPQKTPLSGYQLPTWWHTSQ
What are the official names of this protein?
Putative binding protein BRA0576/BS1330_II0571.
What is the protein family that this protein belongs to?
Belongs to the bacterial solute-binding protein 5 family.
What are the subcellular locations of this protein?
Periplasm.
Protein: AIS_SALHS
Sequence: MLAFTLRFIKNKRYLATLAGALVIIAGLTSQHAWSGNGLPQINGKALAALAKQHPVVVLFRHAERCDRSDNTCLSDSTGITVNGAQDARALGKAFSADIQNYNLYSSNTVRTIQSATWFSAGRSLTVDKKMMDCGSGIYASINTLLKKSQNKNIVIFTHNHCLTYIAKNKRGVKFDPDYLNALVMHAENGKLFLDGEFVPG
What is the function of this protein?
Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core.
What are the official names of this protein?
Lipopolysaccharide core heptose(II)-phosphate phosphatase.
What is the protein family that this protein belongs to?
Belongs to the phosphoglycerate mutase family. Ais subfamily.
What are the subcellular locations of this protein?
Periplasm.
Protein: YFBS_ECO57
Sequence: MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLTVPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTVAGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLVVNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFRDLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVNGVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPESELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGMLAKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLMGKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMMLGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPVSSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF
What are the official names of this protein?
Uncharacterized transporter YfbS.
What is the protein family that this protein belongs to?
Belongs to the CitM (TC 2.A.11) transporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RK23_ATRBE
Sequence: MDGIKYAVFTDKSIRLLGKNQYTSNVESGSTRTEIKHWVELFFGVKVIAMNSHRLPGKSRRMGPIMGHTMHYRRMIITLQPGYSIPPLRKKRT
What is the function of this protein?
Binds to 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L23, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: M1_I72A5
Sequence: MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKDVALSYSTGALASCMGLIYNRMGTVTTEVAFGLVCATCEQIADSQHRSHRQMMTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQIQRFK
What is the function of this protein?
Determines the virion's shape: spherical or filamentous.  Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology.  Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms.
What are the official names of this protein?
Matrix protein 1, M1.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses Matrix protein M1 family.
What are the subcellular locations of this protein?
Virion membrane; Peripheral membrane protein; Cytoplasmic side. Host nucleus.
Protein: SYY_CLOTE
Sequence: MGNNVFDVLKERGYIKQTTHEEEIRDLINKDKITFYIGFDPTADSLHIGHFLPLMMMAHMQKAGHRPIALVGGGTVRIGDPSGKSEMRKMLSKEAIDKNVSSIKSQISRFIDFSDDKAILVDNADWLLNLNYLEFIREIGVHFSVNKMLTAECFKQRLEKGLSFLEFNYMLMQAYDFLCLNRKYGCVMELGGDDQWSNMLAGTDLIRREESKSAYAMTCTLLTNSEGNKMGKTVNGALWLDKDKTSPYEFYQYWRNVDDADVEKCLALLTFLPMDEVRRLAALEGNKINEAKKVLAYEVTKLIHGEDEAKKAEEASEALFGAGKDMSNVPTVNISKDDLGKGILDILVETKILPSKGEARRLIQQGGLSINEEKVTDINMAVTEDLFEENSIIIRRGKKSYNRIVIE
What is the function of this protein?
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
What are the official names of this protein?
Tyrosine--tRNA ligase, Tyrosyl-tRNA synthetase, TyrRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ADP_ADE02
Sequence: MTGSTIAPTTDYRNTTATGLTSALNLPQVHAFVNDWASLDMWWFSIALMFVCLIIMWLICCLKRRRARPPIYRPIIVLNPHNEKIHRLDGLKPCSLLLQYD
What is the function of this protein?
Promotes the release of progeny virus from the host cell nucleus by accelerating the lysis and death of the host cell.
What are the official names of this protein?
Adenovirus death protein, ADP, Early-3 11.6 kDa glycoprotein, E3-11.6K.
What is the protein family that this protein belongs to?
Belongs to the adenoviridae ADP family.
What are the subcellular locations of this protein?
Host nucleus membrane; Single-pass type I membrane protein. Host endoplasmic reticulum membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single- pass type I membrane protein. Note=Initially associates with the endoplasmic reticulum and Golgi apparatus and ultimately localizes to the nuclear membrane.
Protein: ALGJ_PSEFL
Sequence: MTRSLRVLYIGLFLVLLLALGAWSLRSFFGFSTNADATVLNGRWTKAVETHYDEEFPIKRLGTNLWAALDYKLFNEGRPGVVLGRDHWLYSDEEFNPAVNEDQNLEGNYALVEGVRQKLKAQGIQLVMAIVPAKVRLYPEHLGEVKPASIHANLYQDFHARVAADKIIAPDLLGPLQQAKLGGKQVFLRTDTHWTPDGAEIAAKQLAKTIADKTPLNGEPQRFVTEAEKTEPHKGDLRLFLPLDPLFENLMPPKEPLEKRVTHLAETKGDDALFSDSETPVALVGTSYSANPNWNFVGALKQALGSDVISYAEDGHGPILPMLSYLKSDDFKNNPPQVLIWEFPERYLPVNNEIGDADPSWVAQLKQAGSRQQNMALNTPVNHQKSETPDRAQN
What is the function of this protein?
Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization-transport complex and adds acetyl groups at the O-2 and O-3 positions of mannuronate residues.  Acetylation of alginate is important for the architecture of biofilms and increases the ability of alginate to act as a defense barrier (By similarity).
What are the official names of this protein?
Probable alginate O-acetylase AlgJ, Alginate biosynthesis protein AlgJ.
What is the protein family that this protein belongs to?
Belongs to the AlgJ family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Periplasmic side. Periplasm.
Protein: UREF1_BRUC2
Sequence: MIIITPITNDPTTALLRLMAWLSPVFPVGSFSYSHGLERAVHDGLVVDAAGLQDWLQWLVRRGSGWNDAVLCAESWRCAMKGEDLHEIAELAEALAGSRERHMETMLQGGAFLAAARSWPCEIFDRLPPDCAYPVAVGAVAGGHGVPLAQALAAFLQAFCINLLQASIRLSVTGQSGVTAIMAALEPVLGETAARAALSSMEDLGSATFIADIMAMKHETQHSRLFRS
What is the function of this protein?
Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
What are the official names of this protein?
Urease accessory protein UreF 1.
What is the protein family that this protein belongs to?
Belongs to the UreF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_THESQ
Sequence: MAQVDLLNVKGEKVGTLEISDFVFNIDPNYDVMWRYVDMQLSNRRAGTASTKTRGEVSGGGRKPWPQKHTGRARHGSIRSPIWRHGGIAHGPKPRDWSKKLNKKMKKLALRSALSVKYRENKLFVLDDLKLERPKTKFLKEILQNLQLSDKKTLIVLPWKDEGYMNVKLSGKNLPNVKVIIADNPNNSKNGEKAVRIDGLNVFDMLKYDYLVLTQDMVSKIEEVLGNEAGKALTE
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RL13_UREU1
Sequence: MQKSSMLKKEAAIARRQWYLVDATDLVLGRLSVKVADILRGKNKVDYTPNVDAGDYVIIVNSDKVVLTGQKALRENWYNHSHYIGGLRTRSGEEMISKYSDELIRRSVKGMLPKNKLSKQILNKLFIYKNDKHSHEAQQPTILELKLK
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: LPXK_BURP1
Sequence: MSARPGLLARAEARLTREWQRRGALAWALAPFACAFGAIAALRRAAYARGWKARVDCGVPVVVVGNVTVGGTGKTPTVIALVDALRAAGFTPGVVSRGYGAKIAAPTAVTAASPPQQAGDEPLLIARRTLAPVWVCPDRVAAVRALKVAHPEVDVVVSDDGLQHYRLARAVEIVVFDHRLGGNGFLLPAGPLREPLSRRRDATLVNDPYSRALPPWPDTFALSLAPGDAWHLDRPSRRKPLAQFAGERVLAAAGIGAPERFFATLRAAGVAPATRALPDHYAFATNPFVDDHFDAILITEKDAVKLGTSWRDARIWVVPVEAALDPRLIALVVEKLRGRTSA
What is the function of this protein?
Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
What are the official names of this protein?
Tetraacyldisaccharide 4'-kinase, Lipid A 4'-kinase.
What is the protein family that this protein belongs to?
Belongs to the LpxK family.
Protein: HIME_ASPJA
Sequence: MSNSTDPSDYCTFEICPITEAYVYYVPSLAGNAFYLALFAVLLAAQLVLAVRYRTWGYLAGLSGGLILEIIGYIGRIQLHSNPFRFGPYLEYLICLTIGPAILSASIYICLGRIVIVYGEGISRLRPKTYTMVFVACDLVSLVLQAAGGAITSVADADQYDLAQDGINIMIAGLASQVASLALFMALCLDYAWRVYKSPHNLSPETRMRDLRHSLRWKAFLAGLALATVAIFMRSVFRVAELKGGFHSSLANDQVLFMTLEGAMIAIAVIALTVLHPGLCFDGLWDQTKWSFRRSRDSEMQLIEVSAGHEAKAQRADLGMS
What is the function of this protein?
Efflux pump that is probably involved in the efflux of himeic acid A, a ubiquitin-activating enzyme (E1) inhibitor.
What are the official names of this protein?
Efflux pump himE, Himeic acid A biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: MALT_SALSV
Sequence: MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALVTSPAGYGKTTLVSQWAAGKNELGWYSLDEGDNQQERFASYLIAAIQQATGGHCSTSEAMAQKRQYASLTSLFAQLFIELAQWHRPLYLVIDDYHLITNPVIHDAMRFFLRHQPENFTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFNHQEAKQFFDRRLSSPIEAAESSRMCDDVAGWATALQLIALSARQNHTSAHHSARRLAGINASHLSDYLVDEVLDNVDVSTRHFLLKSAILRSMNDALIVRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFSYHPLFGSFLRQRCQWELAAELPEIHRAAAESWMEQGFPSEAIHHALAAGDAQMLRDILLNHAWGLFNHSELALLEESLKALPWESLLENPRLVLLQAWLMQSQHRYSEVNTLLARAEQEIKGVMDGTLHAEFNALRAQVAINDGNPEEAERLAKLALDELPLAWFYSRIVATSVHGEVLHCKGDLSQSLSLMQQTEQMARHHDVWHYALWSLIQQSEIQFAQGFLQAAWETQERAFQLIKEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIAVLSTFQPQQQLQCLTLLVQCSLARGDLDNARSQLNRLENLLGNGRYHCDWISNADKVRVIYWQLTGDKKSAANWLRHTPKPAFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQSGRKNDAQRVLLDALQLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPEMEQHRAQRILREINQHHRHKFAHFDEGFVERLLNHPDVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELAVAATTIKTHIRNLYQKLGVAHRQDAVQHAQQLLKMMGYGV
What is the function of this protein?
Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides.  Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.
What are the official names of this protein?
HTH-type transcriptional regulator MalT, ATP-dependent transcriptional activator MalT.
What is the protein family that this protein belongs to?
Belongs to the MalT family.
Protein: ENO_CAMFF
Sequence: MVIVKKISAIEVLDSRGNPTIKTKVELCDGSIGEAIVPSGASTGKREALELRDGGEAFGGKGVLKAIKNVNSMIAEEICGKDAYNQKAIDDAMLALDGTDNYSRIGANAVLGVSMAVARAAANSLNIPLYRYLGGANACTLPVPMFNIINGGAHANNSVDFQEFMIMPFGFSKFSNALRAATEVYQTLKKILNDLGHSTAVGDEGGFAPNLKDNEEPIKIIMEAIKKAGYKPGEQIKLALDVASSELYDGKTYQIEGKKLTSEELVDRYVKLCDKYPIFSIEDGLSEDDWDGWKILSEKLGDKIQLVGDDLFVTNEKILKEGIEKGIANAILIKPNQIGSVSQTMQTVRLAQRNGYRCVMSHRSGESEDSFIADFAVALNTGEIKTGATSRSERNAKYNRLLEIELETSEFLGDKI
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: PANB_PSEPF
Sequence: MPAITLTTLQSLKQKGEKITMLTCYDATFAHACNEAGVEVLLVGDSLGMVLQGHDSTLPVTTAEMAYHVASVKRGNSDALILADLPFMANATLEQTMTNSALLMQAGAHMVKVEGALWLADSIRLLAERGVPVCAHMGLTPQAVNILGGYKVQGRNENQARQMRADAISLEQAGAAMLLLECVPSELAAEITQAVKIPVIGIGAGSDTDGQVLVLHDMLGLSISGRVPKFVKNFMQGQDSIQSALKAYVSEVKATTFPGIEHGFSA
What is the function of this protein?
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
What are the official names of this protein?
3-methyl-2-oxobutanoate hydroxymethyltransferase, Ketopantoate hydroxymethyltransferase, KPHMT.
What is the protein family that this protein belongs to?
Belongs to the PanB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL4_DROME
Sequence: MSLGNARPLVSVYTEKNEPAKDKNICLPAVFKAPIRPDVVNEVHQLLRRNNRQAYAVSELAGHQTSAESWGTGRAVARIPRVRGGGTHRSGQGAFGNMCRGGRMFAPTKTFRRWHRKVNVNQRRYALVSAIAASGVPALVQSKGHVIDGVSEFPLVVSDEVQKVQKTKQAVIFLRRLKIWADIQKVYKSQRFRAGRGTMRDRRRIARRGPLVVYDKDEGLRKAFRNIPGIETINVDKLNLLKLAPGGHVGRFVIWTESAFARLNDLFGTWKKPSTLKKGYNLPQPKMANTDLSRLLKSEEIRKVLRDPRKRVFRSVRRLNPLTNVRQLIKLNPYAEVLKRRAALAAEKRTVAKVLAKAKKQNVELAKSHFANVATKAAANRAKLLAARKKKVAAKKPAAKK
What are the official names of this protein?
60S ribosomal protein L4, L1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: RIMP_NOSS1
Sequence: MTHPLVPPITDLAIPVAEQLGLEVVGIVFHTNQRPPVLRIDIRNPQQDTGLDDCERMSRALEAALDATEIIPDAYVLEVSSPGISRQLVTDREFISFKGFPVIVSTSPPHEEQQEWIGQLIRRDETKVYINQKGRVIEIPRPLITRVLLYDGE
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PXG5_ARATH
Sequence: MASSISAAEVKVVPEEYNFLQKHVAFFDRNKDGIVYPSETFQGFRAIGCGYLLSTFAAVFINISLSSKTRPGKGFSFSFPIEVKNVRLGIHSSDSGVYDKDGRFVASKFEEIFAKHAHTHRDALTSKELKELLKANREPNDCKGGILAFGEWKVLYNLCKDKSGLLHKEIVRAVYDGSLFEQLEKQRSSKTP
What is the function of this protein?
Calcium-binding peroxygenase involved in the degradation of storage lipid in oil bodies.  May be involved in the interaction between oil bodies and vacuoles during seed germination (By similarity).
What are the official names of this protein?
Probable peroxygenase 5, AtPXG5, Caleosin-5.
What is the protein family that this protein belongs to?
Belongs to the caleosin family.
What are the subcellular locations of this protein?
Lipid droplet. Microsome membrane.
Protein: DNAA_DECAR
Sequence: MSGFWESCLQRFEQELPAQQFNTWIKPLRLEGESTALEDGLRLIAPNGFILKWVRDRYLTRIEDYSRTFFEGPVTIALVIGSGKATAARIQATTTDSGQNAPANPATTSEKRTAASEKARGKGSNYEKSRLFPSFTFDNLVVGKANDLARAAAVQVANNPGGAYNPLFIYGGAGLGKTHLIHAIGNTIATENPEKIVRYVHAEDYYSDVVRAYQQKSFDSFKRTYRSLDVLLLDDVQFFNGKNRSQEEFFFLFNALIEARKQIIITCDTYPKDINGLDDRLVTRFDWGLTVQIEPPELEMRVAILKKKAEAEGIQLDDEVAFFIAKHLRSNVRELEGALKKVLAYSSFHGRVIALDLAKEALKDVIGSVRNVGMDNIQKTVADYYKIKVAELFSKKRTRAIARPRQVAMWLCREVTSHSFPEIGDAFGGRDHTTVIHAVKTIDSLRIKENELNHDLHVLLQVLKG
What is the function of this protein?
Plays an important role in the initiation and regulation of chromosomal replication.  Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'.  DnaA binds to ATP and to acidic phospholipids.
What are the official names of this protein?
Chromosomal replication initiator protein DnaA.
What is the protein family that this protein belongs to?
Belongs to the DnaA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YCAR_SHISS
Sequence: MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLETEARVLTADESKS
What are the official names of this protein?
UPF0434 protein YcaR.
What is the protein family that this protein belongs to?
Belongs to the UPF0434 family.
Protein: PK1IP_HUMAN
Sequence: MELVAGCYEQVLFGFAVHPEPEACGDHEQWTLVADFTHHAHTASLSAVAVNSRFVVTGSKDETIHIYDMKKKIEHGALVHHSGTITCLKFYGNRHLISGAEDGLICIWDAKKWECLKSIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPRGEQYVVIIQNKIDIYQLDTASISGTITNEKRISSVKFLSESVLAVAGDEEVIRFFDCDSLVCLCEFKAHENRVKDMFSFEIPEHHVIVSASSDGFIKMWKLKQDKKVPPSLLCEINTNARLTCLGVWLDKVADMKESLPPAAEPSPVSKEQSKIGKKEPGDTVHKEEKRSKPNTKKRGLTGDSKKATKESGLISTKKRKMVEMLEKKRKKKKIKTMQ
What is the function of this protein?
Negatively regulates the PAK1 kinase.  PAK1 is a member of the PAK kinase family, which has been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA.  PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain.  PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.  May be involved in ribosomal large subunit assembly (PubMed:24120868).
What are the official names of this protein?
p21-activated protein kinase-interacting protein 1, PAK/PLC-interacting protein 1, hPIP1, PAK1-interacting protein 1, WD repeat-containing protein 84.
What are the subcellular locations of this protein?
Nucleus, nucleolus.
Protein: MLIC_YERE8
Sequence: MKHLFGTTAVLGTAAVLMLTGCSLVQPKNETLHYQCGGTKLTVMQDNKQDKVSLVLDGKQLTLPQVRAASGAKYSDNHYTFWSKGNTAFVERDEKVIINDCRLLTTPNDSILQGEDR
What is the function of this protein?
Specifically inhibits C-type lysozymes.
What are the official names of this protein?
Membrane-bound lysozyme inhibitor of C-type lysozyme.
What is the protein family that this protein belongs to?
Belongs to the MliC family. Type 1 subfamily.
What are the subcellular locations of this protein?
Cell outer membrane; Lipid-anchor. Note=Anchored to the periplasmic side.
Protein: RL34_PORG3
Sequence: MKRTYQPSNRKRLNKHGFRSRMATANGRRVLAARRAKGRAKLTVSDEFVG
What are the official names of this protein?
50S ribosomal protein L34.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL34 family.
Protein: TDH_AGRRK
Sequence: MSNMMKALVKSKPEVGLWMEHVPVPEVGPNDVLIRVRKSAICGTDVHIWNWDQWAQKTIPVPMVVGHEFCGEIAEIGSAVTKYHVGERVSGEGHIVCGKCRNCRAGRGHLCRNTLGVGVNRPGSFGEFVCIPESNVVPIPDDIPDEVAAIFDPFGNAVHTALSFDLVGEDVLVTGAGPIGIMGAMVAKRSGARKVVITDINPNRLALAHKLGIDHVVDASKENLADVMKSIGMTEGFDVGLEMSGAAPAFRDMIDKMNNGGKIAILGIAPAGFEIDWNKVIFKMLNLKGIYGREMFETWYKMIAFVQGGLDVSPVITHRIGIDDFREGFEAMRSGNSGKVVMDWF
What is the function of this protein?
Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
What are the official names of this protein?
L-threonine 3-dehydrogenase, TDH.
What is the protein family that this protein belongs to?
Belongs to the zinc-containing alcohol dehydrogenase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPF_SHEON
Sequence: MKIRIGHGFDVHKFGEPRPLILCGVEVPYETGLVAHSDGDVVLHAISDAILGAMALGDIGKHFPDTDAAYKGADSRVLLRHCYALAKAKGFELGNLDVTIIAQAPKMAPHIEDMRQVLAADLNADVADINVKATTTEKLGFTGRKEGIAVEAVVLLSRQ
What is the function of this protein?
Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds.  Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MECDP-synthase, MECPP-synthase, MECPS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
Protein: RNPH_ECO24
Sequence: MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN
What is the function of this protein?
Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation.  Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important.  Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
What are the official names of this protein?
Ribonuclease PH, RNase PH, tRNA nucleotidyltransferase.
What is the protein family that this protein belongs to?
Belongs to the RNase PH family.
Protein: RS14_SALTO
Sequence: MARRSLSNRQARREELVARHADRRAELKRLIAHPDTDPDVRADAVRQLARLPRDSSPVRLRNRDVIDGRPRGVLTRFGLSRVRFREMALRGELPGIRKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: GLNB_MYCBO
Sequence: MKLITAIVKPFTLDDVKTSLEDAGVLGMTVSEIQGYGRQKGHTEVYRGAEYSVDFVPKVRIEVVVDDSIVDKVVDSIVRAARTGKIGDGKVWVSPVDTIVRVRTGERGHDAL
What is the function of this protein?
In nitrogen-limiting conditions, when the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP.  P-II-UMP allows the deadenylation of glutamine synthetase (GS), thus activating the enzyme.  Conversely, in nitrogen excess P-II is deuridylated and promotes the adenylation of GS.  P-II indirectly controls the transcription of the GS gene (glnA).  P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA.  When P-II is uridylylated to P-II-UMP, these events are reversed (By similarity).
What are the official names of this protein?
Nitrogen regulatory protein P-II.
What is the protein family that this protein belongs to?
Belongs to the P(II) protein family.