PharMolix/UniProtQA huggingface dataset:
Protein: LPXB_PSESM
Sequence: MTSPLRIALVAGEASGDILGSGLMRALKARHPDVRFIGVGGPLMEAEGMQSYFPMERLSVMGLVEVLGRLRELLARRKLLVQTLIDEKPDVFIGIDAPDFTLNIELQLRRAGIKTVHYVSPSVWAWRQKRVLKIREGCDLMLTLLPFEARFYEEKGVPVRFVGHPLADTIPLESDRGATRAELGLSVDGPVVALMPGSRGGEVGRLGALFFDAAERLLVERPGLRFVLPCASPQRRAQVEQLLQGRDLPITLLDGRSHVALAACDAVLIASGTATLEALLYKRPMVVAYRMAPLTFWVLKRLVKSPYVSLPNLLAQRLLVPELLQDDATPEALARTLLPLIEDGHAQTEGFDAIHRILRRDASNQAADAVLSLLGLPLSL
What is the function of this protein?
Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
What are the official names of this protein?
Lipid-A-disaccharide synthase.
What is the protein family that this protein belongs to?
Belongs to the LpxB family.
Protein: Y040_OSHVF
Sequence: MDDEDDFFNFLSEKPTDKEQSMLDDIFKMGNDTEDIFSRLNEFLSNDINLTPNNEETYTNRFNYDASVSLLDNVGRAASFNTYYRDGQEFRSHLHGQVMDDESEHIVASLEEECYKRGNKYFVSDFIYYDTETNSWTPKREELSKIGLEKDIKADVICVDKIKVWTGPRSEHLMSIQNATNSLSGYEKRDSMNKPPKGMFLHEVVKFGDLMGTMARYKRTDNTQSSHPFSENNRTNRTNVNMARGIHEFTLLNRIMMAHNIANNPYGGSSTLISRDSENNNSLTVDSVINSVINGITFKAEACKKEKKGEKKGFSLTQMASFGTHKSVVNFNEQDLEEIANMTEEELALAPLEGAEVQVHEACFNCSAVRGSRILPDMKRKGCQLLEDTKESITSLAVNNGKAKIMKMSNSLAWNSLNTLIDMMCWEANTHKMTREEEMEFFNTEITPALNGLHVSRDNYAQASSFTQQIPKNKFLAEPDIKSVSHKHKSVRTRNIFGQTNIKFKTAHRKVGELNNKKPMTGEKPPPKNKKSPKYKNNTFASQWARNMGIVRFLEFGPRVCRNRCDFREPTEEEI
What are the official names of this protein?
Uncharacterized protein ORF40.
Protein: CYC23_RHOTP
Sequence: QEAPKAFNQCQACHKVEAGEDGVGPSLFGLFGHKLGQAPGFKYSEAHLKFAQQTVDEPFLTKYLADPKASLPGNKMVFAGLKNPDDVKAVLAYLKTIK
What is the function of this protein?
Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway.  However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria.
What are the official names of this protein?
Cytochrome c2.
What is the protein family that this protein belongs to?
Belongs to the cytochrome c family.
What are the subcellular locations of this protein?
Periplasm.
Protein: ACCD_LACLA
Sequence: MALFQKKKYIKINPNRSIIEKQAEQPEVPDELFAKCPACKHTIYQKDLGKNKVCPNCDYNFRITAKERLAIVADKDSFVEMFTGIESKNPLDFPGYPEKLAATKARTGLDEAVITGTATIKGQKTALAIMDSTFIMASMGTVVGEKLTRLFEYATTEKLPIIVFTASGGARMQEGIMSLMQMAKTSAAVKRHSNAGLFYITVLTDPTTGGVTASFASLGDIILAEPQSLIGFAGRRVIEQTVRQTLPDDFQKAEFLLNHGFVDAIVKRTELRQKLALLLELHTEVENV
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPA2_SYNC1
Sequence: MKDTLPSATQVLKEAFDTLDSALENFSPVLAVQHVGWVEYIGKGIARVGGLPGVRCEELLAFPGGLLGLALDADEDQVGVVLFGDYTHLQAGDEVRRTGRVLDVPVGDGLIGRVVNPVGRCLDGGKPVAFQRQLPVERPAPPIMDRLPVTQPLMTGIKVIDALIPIGRGQRELILGDRQTGKTAIAIDAIINQRDQDVVCIYCAIGQRAASVAGVVTELRNCGALDYTIVVVAEGDAPPGLQYIAPYAATSMAEHFMEHGRDVLIVYDDLTRHARAYREISLLLRRPPGREAFPGDIFYVHSRLLERATHLNEPRGGGSLTALPIIETEAQNLSAYIPTNLISITDGQIYLSPELFQKGLLPSVDVGKSVSRVGGKTQLAAYRAVAGDLRLTYAQFEELEAFARFGTRLDEETRQVLHRGRRVRAILKQTQSSPRTAPQQVLVLHSLNSGVFDTVDEEALPAAEQAICAAVSEIPEIVDKILQGKTLSQEDLDVMHTVAKRVTRPFIKLGEEGHAGAAGDAT
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha 2, ATP synthase F1 sector subunit alpha 2, F-ATPase subunit alpha 2.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: YYBJ_BACSU
Sequence: MIEVLNLTKKIKKTTVLDNISYTFEKGTIYGLFGSNGSGKTMLLRALSGLIVPTEGSITIKGEQLHKDISFPKSVGLIIENMQLLPQYDAFTNLKILSKIKKIASDNDILDSISRVGLENFNSVKVSKFSLGMKQRLNIAQAIFEKPDILLLDEPTNAIDEKGVAFVHDILLQEKKRGATIIITSHHKEDIISLCDIALEMNHGRLETSEKVIYKKDS
What are the official names of this protein?
Uncharacterized ABC transporter ATP-binding protein YybJ.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily.
Protein: SRK2H_ARATH
Sequence: MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA
What are the official names of this protein?
Serine/threonine-protein kinase SRK2H, OST1-kinase-like 9, SNF1-related kinase 2.5, SnRK2.5.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: ALAE_CROS8
Sequence: MSQELNSMFSPHSRLRHAVADTFAMVVYCSVVGMMIEIFVSGMSFEQSLSSRLVAIPVNMVIAWPYGLYRDAVMRLAARVGKGRLVRNLADVIAYITFQSPVYAAILLFVGADIPQIITAVSSNIVVSMMMGAAYGYFLDYCRRLFRVSPAAPVSAQA
What is the function of this protein?
Exports L-alanine.
What are the official names of this protein?
L-alanine exporter AlaE.
What is the protein family that this protein belongs to?
Belongs to the AlaE exporter family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRE_PROMM
Sequence: MSPLPPSAEACRNELLNRLAREAYRHGDFTLASGRQSNHYVNCKPVSLSGSGLALLGLALLKYVEPDAVCVAGLTLGADPLVSAVAMAAAQAERTLNALIVRKQAKGHGTAAWLEGPLPPSGARITVLEDVVTTGGSSLKAVQQLRETGYLVTRVVTIVDRQEGGEEALNAAELELVSLYQLNQVAERARQLETET
What is the function of this protein?
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
What are the official names of this protein?
Orotate phosphoribosyltransferase, OPRT, OPRTase.
What is the protein family that this protein belongs to?
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Protein: YM4C6_STAAR
Sequence: MLELITDFSKKSFKNYSMKEELKFNAINIIYGVNGRGKTSLARGIKEIIEENNPDSLRYFYTDYIHELLLLEDSNKFKGVKATFGTKNVEIENKIIKLKNEVVDMTDTKKLLVEKRRKLRELINEIHKSRKGNLKIPLKSSNKSIEEVIAIYEKNLKDAKKIEHNIESIRNFVANDETLYNKYNSIYEVMIPSLKIETYDVDRLTKILQNNYTDIKIPSFEVIDWLRNGLELHNVEESICKFCGNNLNYNLIKEKIEIYLLNEKKKDFDYLKDVEKSIEQLSDNYEQYLSNIDIFVNELGVQKSVEESLGDSIDEIKRILKQKLGNMENDNLKFPSDDYITLISRLSEIEEECKEKKKIKLKELNKKTENINVIVTGSISLEILENQSIREELSSIQYEENECKKQEQLNEEINAKISKLHENQSDYNDFKIYLNGVFESINLHIRLKSDETTQNYYLYHDLENISLNIKDISEGEKNLIAFLFFYFELFEDEKQETIKSNIKTLIIDDPINSFDEANRFYVLELIKKVLKSKFNQIFIFTHSWNDFCDITYRLKGEDHNFYEVYKDHQGTSFLEKFKKVKTPYKKLFQEIYELSRKSQKDIVEEDCYYYHSINSIRRVFEEFLSFKLKNSDLAQKSNQPEIEEVYRKMTGNEMSNNKKIKLGSFLTIINVLSHKPYRAIDVIGSAKFLMRYIEDVDKAHYDAMKD
What are the official names of this protein?
Uncharacterized chromosomal cassette SCCmec type IVc protein CR006.
Protein: GCH1_HELP2
Sequence: MENFFNQFFENIGEDKNREGLKETPKRVQELWKFLYKGYKEDPKVALKSAYFQGVCDEMIVAQNIEFYSTCEHHLLPFLGNISVGYIPKEKIVGISAIAKLIEIYSKRLQIQERLTTQIAETFDEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDPKTRAEFMQLLKS
What are the official names of this protein?
GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP-CH-I.
What is the protein family that this protein belongs to?
Belongs to the GTP cyclohydrolase I family.
Protein: DAT11_ORYSJ
Sequence: MVGSDGDGDGGGGEAHAPAAPAHHHRRPPRPRGGSGAIVEGFAAALRRRIRSGAAAAARASFGGDSGDEAASGEPSSSSSSSPSRRRGGDSNGAEASSAAGGGGGRGGGGDFSAFTFRAAAPVHRKAKESPLSSDAIFKQSHAGLFNLCIVVLVAVNSRLIIENLMKYGLLIRAGFWFNDKSLRDWPLLMCCLSLPAFPLGAFAVEKLAFNNVITDAVATCLHIFLSTTEIVYPVLVILKCDSAVLSGFLLIFIACIVWLKLVSFAHTNHDIRQLTMGGKKVDNELSTVDMDNLQPPTLGNLIYFMMAPTLCYQPSYPRTSCVRKGWLIRQIILYLIFTGLQGFIIEQYINPIVVNSQHPLKGGLLNAVETVLKLSLPNVYLWLCMFYAFFHLWLSILAEILRFGDREFYKDWWNAKTIDEYWRKWNMPVHKWVVRHIYFPCMRNGISKEVAVLISFLVSAVLHEICVAVPCRILKFWAFLGIMLQIPLIVLTAYLKSKFRDTMVGNMIFWFFFCIYGQPMCLLLYYHDVMNRIEKAR
What is the function of this protein?
Involved in triacylglycerol (TAG) synthesis.  Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA.
What are the official names of this protein?
Diacylglycerol O-acyltransferase 1-1, OsDGAT1-1.
What is the protein family that this protein belongs to?
Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RL17_SHESR
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMASSLVRHEIIKTTVAKAKELRRVVEPLITLAKSDSVANRRLAFARTRDAEVVGKLFTELGPRYQERPGGYTRILKCGLRAGDKAPMAYIELVGRPEAAQAVEVEAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: YD018_HUMAN
Sequence: MKPDWPRRGAAGTRVRSRGEGDGTYFARRGAGRRRREIKAPIRAAWSPPSAAMSGLQSGRRWRPQGTGTGARAAGALAALRLGPRLRAAPLLAPLWLLAPTPDSHMTPAPLALRASRGWRENNLSDYQYSWMQKC
What are the official names of this protein?
Putative uncharacterized protein FLJ13197.
Protein: ILVD_SODGM
Sequence: MPKYRSATTTHGRNMAGARALWRATGMTDDDFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEASGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLLDKIIKLDLIDAMIQGANPDVSDEDSNQIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLNAGERIVGLAKRYYEQDDTSALPRSIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEGEVDFTMADIDRLSRKVPHLCKVAPSTQKYHMEDVHRSGGVIGILGELGRSGLLNGDVHNVLGLSLPETLARYDVMVSDDAAVKSMYAAGPAGIRTTQAFSQDCRWPSLDTDRQEGCIRAREFAYSQDGGLAVLYGNIAEDGCIVKTAGVDKGSLVFRGPAKVYESQEAASEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTTFLKSVGLGKSCALITDGRFSGGTSGLSIGHVSPEAASGGLIGLVRDGDIIDINIAGRGIVLDVADSELAARRETELARGAAAWTPVARERQVSFALKAYASLATSADKGAVRDKAKLGG
What is the function of this protein?
Functions in the biosynthesis of branched-chain amino acids.  Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
What are the official names of this protein?
Dihydroxy-acid dehydratase, DAD.
What is the protein family that this protein belongs to?
Belongs to the IlvD/Edd family.
Protein: FRBH_BLOB1
Sequence: MSQQEAVDAAFLPTLDLSRLVSSDAEERQKLVRACEVYGFFYLDLRSDAELIALWTGVLDLMGQYFNLSLDEKMRDSRNSDTHGYEPVATSTGAQDDLPDYYESLKASRDEVLTQSSKLAPAVKANHALLNRFIERAHAVTMMILRQLSIALELDDSHKFEAFHRHSEESLSTLSMFRYPKQEVLDVGVGHNKHTDIGTLTFLLCQQQGLQVLSKDPVGWRFVQPLPGCAVINVGDTLRFLSGSRFRSAVHRVIPVDQLQRQDRFSIAYFLRAENNATLNAVGGRTVSAKDWHDEKFDVFRKSREAQASDDVLTGGMERDM
What is the function of this protein?
2-oxoglutarate-dependent dioxygenase; part of the gene cluster that mediates the biosynthesis of the antifungal antibiotic FR901469, an inhibitor of beta-1,3-glucansynthase, exerting antifungal activity against the pathogenes Candida albicans and Aspergillus fumigatus (PubMed:27660098).  FR901469 is a cyclic depsipeptide containing 12 amino acid residues and a fatty acid chain (PubMed:27660098).  The NRPS frbI contains 12 modules responsible for the formation of the depsipeptide backbone which is denoted as Acyl-Thr-Ala-Tyr-Val-4OHPro-Thr-Thr-3OHPro-threo3OHGln-Gly-Thr-Orn-OH (C71H116N14O23) (Probable).  The PKS frbB is probably involved in the production of the hydrocarbon chain, and the acyl-CoA ligase frbC might be involved in the transport of the chain to the peptide ptoduct of frbI (Probable).  Because FR901469 contains 3 hydroxylated amino acid residues, the 3 oxygenases frbA, frbH, and frbJ might be participating in amino acid hydroxylation (Probable).  As no thioesterase domains were detected in frbI or frbB, the thioesterases frbD and frbE may instead release and cyclize the products of the NRPS and PKS, respectively (Probable).
What are the official names of this protein?
2-oxoglutarate-dependent dioxygenase frbH, FR901469 biosynthesis cluster protein H.
What is the protein family that this protein belongs to?
Belongs to the iron/ascorbate-dependent oxidoreductase family.
Protein: RPOB_PARP8
Sequence: MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQAEVPTAQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYMLSPPAFNIKECQQRGLTYCSALRAKVRLVLLDKESPSKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDVLYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMPEGAQMEFVPERLRGEVARFDITDRDGKVIVQKDKRINAKHIRDLENAKTKYISVPEDYLLGRVLAKNVVDGDTGEVIANANDEVTESVLDKLREAKIKDIQTLYTNDLDQGPYISSTLRIDETADKMAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEEAYDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVTDGKVTDQIDYLSAIEEGRYVIAQANAAVAEDGTLTDELVSSREAGETLMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTVAVDSGTTVQALRGGVVDYVDAGRIVIRVNDDEAVAGDVGVDIYNLIKYTRSNQNTNINQRPIAKVGDKVARGDVLADGASTDLGELALGQNMLVAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLARMLEGKVANGGPKKLAKGTKIERAYLEDLDHYHWFDIRLADEEAAAQLEAIKDSIEQKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQARIEEVRAFLTKIYNESGRAEELESFSDDEILELAKNLREGVPFATPVFDGATEEEMSSMLDLAFPDDIAQNLGMTKSKNQVRLYDGRTGEAFERTVTVGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN
What is the function of this protein?
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
What are the official names of this protein?
DNA-directed RNA polymerase subunit beta, RNAP subunit beta, RNA polymerase subunit beta, Transcriptase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the RNA polymerase beta chain family.
Protein: PIGC_DICDI
Sequence: MNDHHLNHRIINNINASSSSSSSSSPVQTNININSANNTNNNNNNNNNNNNNNNNNNNNIDNKWKKNLYEKQPYSDNYTDETFLIGLVQNANFIKYDFWTVVLDSFTVSQQITSVILFAIIFFHSLKHTLTLPFLVAMAGGFLVLGYIAIIIIDPSANFLSIRSSFLHIILLFGTVYGLSPVLRTLTNSFSDDTIWALTFILLLAHLFFHDYGYTNNESQKFSAPVSLNAAIFASVLLGSRLPSNIHVFVLISYAIETFALFPIFRHHLKRHSMELHVGLTVILCVTCSLLLLGMSKLLALIYIGIIGTITFVCPLWLIFIQKYKNEINGPWDEASVISQSGGEF
What is the function of this protein?
Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
What are the official names of this protein?
Putative phosphatidylinositol N-acetylglucosaminyltransferase subunit C, Phosphatidylinositol-glycan biosynthesis class C protein, PIG-C.
What is the protein family that this protein belongs to?
Belongs to the PIGC family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: RIMM_SYNC1
Sequence: MVLQQSDLLILGVVIGTHGLRGDLKIRGSDQDFPLLSKMHQLVFLREGETVLKCARRKAGWYKGHLLLQIAGYRDVRAVQHLVGCEVAVRRDDVPGLPAGEYYWFQLKGMTAVDRRLGALGCLEDIFTTAAHDIYVINGDYGEVLVPAVKAFIADVDLESNRILFDLPDGLVQET
What is the function of this protein?
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region.  Probably interacts with S19.  Essential for efficient processing of 16S rRNA.  May be needed both before and after RbfA during the maturation of 16S rRNA.  It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
What are the official names of this protein?
Ribosome maturation factor RimM.
What is the protein family that this protein belongs to?
Belongs to the RimM family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PROF2_MALDO
Sequence: MSWQAYVDDHLMCEIEGNHLSAAAIIGHNGSVWAQSATFPQLKPEEVTGIMNDFNEPGSLAPTGLYLGGTKYMVIQGEPGVVIRGKKGPGGVTVKKSTMALLIGIYDEPMTPGQCNMVVERLGDYLIEQGL
What is the function of this protein?
Binds to actin and affects the structure of the cytoskeleton.  At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.  By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity).
What are the official names of this protein?
Profilin-2, GD4-2, Pollen allergen Mal d 4.0201.
What is the protein family that this protein belongs to?
Belongs to the profilin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton.
Protein: FURH_ARCFU
Sequence: MWKERAMEEMKKAGLRLTPQRLKLIEVIEKIGGRHPTLKEVYEEVVKEFPTMSFSTLYSNLLIFRGLGLLDFFTLEGETRVEVNCEPHFNVIEREEIRDFVDEELIGEIERRLGRNVKVVNVFMEDRD
What are the official names of this protein?
Ferric uptake regulation protein homolog.
What is the protein family that this protein belongs to?
Belongs to the Fur family.
Protein: NU4LM_TAMTE
Sequence: MSSIYMNILLAFTMALLGLLMYRSHLMSSLLCLEGMMLSLFILSTVTMLNTSFTLSSMMPVMLMVFAACEAAVGLALLVTVSNTYGLDYVQNLNLLQC
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 4L, NADH dehydrogenase subunit 4L.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 4L family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: TPMT_SHEB8
Sequence: MEPGFWHEKWHQQQIGFHQQDINPFLVKYWQQLGLPADTQVFVPLCGKSLDMCFLAEQGHQVIGCELNELAVQHFFSDNQLEMTQTTVGEHQHYHTEQISLYQGDIFTLPKTITQAVTAFYDRAALIAWPESMRAQYAKQLASLLPSGSVGLLVTLDYPQEALSGPPFAVSPTWVEQHLSDDFDIEVLASQDVLADNPRFIKKAVPWLNEAAYLLKRK
What are the official names of this protein?
Thiopurine S-methyltransferase, Thiopurine methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FTHS_STRP7
Sequence: MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDKIRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRRILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRRLANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIAHGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRALKMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVLKELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEKIVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEITIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: MXC_DANRE
Sequence: MSSFDSAEGECNGLNQHYEKKVRPIIDLVDTLRALGVEKDLNLPAIAVIGDQSSGKSSVLEALSGVALPRGIGIVTRCPLILKLKKITRDKNWSGLLTYKDQTEILKEPTGIENAVLKAQIALAGTGEGISHEMITLEIQSCDVPDLTLIDLPGIARVATGNQPEDIEKQIKDLIEKFIKRQETISLVVVPANIDIATTEALKMASTVDPTGQRTLCILTKPDLVDRGMEDTVVRTVNNEVIRLEKGYMIVKCRGQQDINDKLNLVEALEKERRFFDEHPQFSSLLEDGKATIPLLGQRLTEELVEHIAKNVPRLQNQIEMKLQKTFERLKVLGESVPDDDEIELNNFLIKKLRQFMDALEEVKRVEEEPVKSDTRVFSKIRQEFVSWKHILDSKPIKMSTDLQEYVRTHRGKELPGFLNYGTFAGIIRMHVEDLEEPALKLLRNAKDIVHSSVGSIANIHFNGYPNLLLAVKEPIEKCLHEQFQNAEEKIRSQFKLEKTVYCQDDLYTNHLNLLRPKNTVRFGLEASLGNSELRETAFHLTSYLTIACERLANQIPLIVQYHMMNEYNSQLQNAMLGLIGTSDPGMLLCEDSGVARIRKDLKERLERLKDARRALPKVVHSANSW
What are the official names of this protein?
Interferon-induced GTP-binding protein MxC, IFN-inducible antiviral protein MxC, Interferon-inducible MxC protein.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: H2X01_CYRHA
Sequence: MKMTLIAIPTCAAVLVLHTTAAEELEAESQLMEVGMPDTELEAVDGERLFECSVSCEIEKEGNRDCKKKKCKGGWKCKFNMCVKV
What is the function of this protein?
Postsynaptic neurotoxin.
What are the official names of this protein?
U4-theraphotoxin-Hhn1p, U4-TRTX-Hhn1p, Hainantoxin-II-24, HNTX-II-24.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 12 (Hwtx-2) family. 02 (Hwtx-2) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: AMAN2_AMAEX
Sequence: MSDINATRLPVFSLPVFFPFVSDDIQAVLTRGESLC
What is the function of this protein?
Cyclic nonapeptide that belongs to the MSDIN-like toxin family responsible for a large number of food poisoning cases and deaths (PubMed:24050899).
What are the official names of this protein?
Amanexitide proprotein 2.
What is the protein family that this protein belongs to?
Belongs to the MSDIN fungal toxin family.
Protein: DLP1_SCHPO
Sequence: MSFPFASLLKRPSAISSLLSLKKPGSWSSILLKAVGVLSRDSRWHSDLLKMLTEEMDSLNGQINTWTDNNPLLDEITKPYRKSSTRFFHPLLVLLMSRASVNGDPPSQQLFQRYKQLARVTELIHAANIIHINIGEEQSNEQIKLATLVGDYLLGKASVDLAHLENNAITEIMASVIANLVEGHFGSRQNGSVGLSNERTILLQSAFMPAKACLCASILNNSSQYINDACFNYGKFLGLSLQLAHKPVSPDAQVLQKNNDILKTYVENAKSSLSVFPDIEAKQALMEIANSVSK
What is the function of this protein?
Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
What are the official names of this protein?
Decaprenyl-diphosphate synthase subunit 2, All-trans-decaprenyl-diphosphate synthase subunit 2, Decaprenyl pyrophosphate synthase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the FPP/GGPP synthase family.
Protein: RUVC_BIFLD
Sequence: MIILGVDPGLTRCGVGVIEAGEHRRLSFIHVDVVRSSPDITQDLRLLAIYNGLSEKMDRFAPDAVSIERVFAQSNRNTVLGTAQAAGLAMLAAAQRNIPVALHTPTEAKLAITGNGQAQKIQVERMVTRILNLTKMPTPADAADALALAICHALRPAGALQGGEREQHLTAAQRQWAEAAQNSTRRRINHDRGM
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: NCPP_ECO45
Sequence: MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQPFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENTSQRGEARSATLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRTSVYHQAVILALSPFHNAVYQPLQA
What is the function of this protein?
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives.  Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
What are the official names of this protein?
Inosine/xanthosine triphosphatase, ITPase/XTPase, Non-canonical purine NTP phosphatase, Non-standard purine NTP phosphatase, Nucleoside-triphosphate phosphatase, NTPase.
What is the protein family that this protein belongs to?
Belongs to the YjjX NTPase family.
Protein: Y131_UREPA
Sequence: MNQIKMNKSFAEFSKLPKIKQVFTPWFIAALVIFIVGLTIAFTMVGLLNEGFENARALVNDQGQIIGKVADVSGDNHSLMSWLGYDQHANYQELYKTIHDQLINGKTMESLINNTNKNNDPKLYEALHYHAHSKFINHNGTWGFVTKVLSDWENSWFYKYNQLFSQLANSQNPVLAAQGIKSLAKLSTIIQYQNPNYIAYNWVFIVFMMPQMITFIIIVVKLATVFSPKKSAEEKQAYKLAKLEVKNQKKAKKLNNSLQQINLNLEAN
What are the official names of this protein?
Uncharacterized protein UU131.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.