PharMolix/UniProtQA huggingface dataset:
Protein: CMR1_VANPO
Sequence: MVELTEFQKRRQENIKRNNDLLKKLHLGGAASRIKREAGVDDTHRTVVKKKKSPSVSRGRSASPKVAPVATRRSMRLRGEKVDNVGIPNVSDTQLMKMSLDGTSGSSVNDKELVDEIKDTPVIGDVKLSDLIKDEKEENLIEKFKSFANKNFSSGDFFEEIRKRQMENKAPELQKLQDDFDLQLYDVFQPNEIKLVYERITATYFHPSLDKKLIVAGDTSGNIGLWNVRDEPLSENGEDQMVEPDITKVKFFTKNVGKIDCFTSDTSKLLTASYDGSLRSIDLNSLQSNDILTLRNEYDDPLGISDFQFSYENPNVLLMTTLSGEFVNIDLREKIGEQISSNLRRLSDKKIGSFSINPNRPYEIATGSLDRTLKIWDIRKLVKKPEWSQYEDYDSCEIVSVYDSRLSVSAVSYSPTDNTLVCNGYDDTIRLFDVGSDNLPDDLQPKLTLKHNCQSGRWTSILKARFKQDQDVFAIANMKRAIDIYDSQGQQLAHLPTATVPAVISWHPLRNWIAGGNSSGKIFLFTDETVKKEEEE
What is the function of this protein?
DNA-binding protein that binds to both single- and double-stranded DNA.  Binds preferentially to UV-damaged DNA.  May be involved in DNA-metabolic processes.
What are the official names of this protein?
DNA damage-binding protein CMR1.
What is the protein family that this protein belongs to?
Belongs to the WD repeat DDB2/WDR76 family.
Protein: MNMA_PSEF5
Sequence: MRDPAPSDTQKKRVIVGMSGGVDSSVSALLLMEQGYQVEGLFMKNWEEDDGTEYCTAMDDLADAQAVCDKIGIKLHTANFAAEYWDNVFEHFLAEYKAGRTPNPDILCNREIKFKAFLDYAMMLGADLIATGHYVRRRDIDGRTELLKGLDPNKDQSYFLHAVGGEQIAKTLFPVGELEKPEVRAIAEKHDLATAKKKDSTGICFIGERRFSDFLKQYLPAQPGEIKTTEGEVIGRHHGLMYHTIGQRQGLGIGGLKDAGEEPWYVLIKDLEHNELIVGQGNDHPWLFSRALLASDIYWVNPIDLSLPRRLTAKVRYRQSDQPCTLEKTTNGYRATFDDPQRAVTPGQSVVFYDGEICLGGGVIEVAEPWSSKDARP
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: IHFB_PECCP
Sequence: MTKSELIERLAGQQSHIPAKVVEDAVKEMLEQMASTLAEGDRIEIRGFGSFSLHYRAPRVGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG
What is the function of this protein?
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
What are the official names of this protein?
Integration host factor subunit beta, IHF-beta.
What is the protein family that this protein belongs to?
Belongs to the bacterial histone-like protein family.
Protein: ADDB_SYMTH
Sequence: MRFIIGGAGSGKSQRCLDELTQAAQAAPAGPPLILLVPEQATFQVEQALLGSGRLKGIIRAQVLSFQRLAWRVSLKAGGLALPPLSDLGKQMVLRALLEKKRDDLRLFHQVADKPGFIERVAGSIRELRSYRQGPESLRRQLSQLEAEGLGETSLGAKLHDLALVMDELRSYIEGRFTDPDEYLTVLAARLEESRLLEGAEVWVDGFNGFTPQELAVLGAVMRSARQVHISLCIPPGQLYKAGGHHSPSDLFHPVLSTYDQLMQLAAESGVAVDPPLYLNEPLRFRGAPELAHVERYLFRQSAPAWPGAPERIALVEAQNRREEVAAAAREILRLVREEGLRFREIAVVARDLEGYGDLAATLFAEHGIPAFIDRRRTVAHHPLVELLRAALEVVVQDWAYGPVFRYLKTDLTGVSRAEIDLLENYVIEHGIRGRAWQQQEPWQYLRRYTLEEDAVPAGPAQQALLDEIHRIRRRATAPLLAFQRRLQRRGRPGPTVREITTYLFQLLDDLKVARQLEAWKAEAEQRGDLETAREHEQVWTRVLELFDQIVEGLGDQVLSPKVYLQVLSAGLDGLKLGLIPPGLDQVIVGTVERSRHAGVRATLILGATEKDFPPQPAEDAIFTDRERERLKQSGLDVGPTSLERLFQEQFLTYVALTRGSDFLWISYPLADESGRAAAPSPVVGRMRRLFPELKPRPAAPPAPDAEAAVAQVATPRQLAAAVARALRRARSGYAVEPHWLDLYQCIVLDPDLHREGAAVLAAVGYEEWLRRRGTPVGRELARLLYGDRLVTSVSRLEAFLSCPFRHFAGYALRLQGRAEFTVSAPEFGLFYHAALSLFVRELERDGLAWDTLTPDEAWRRMDSIIDRLAPRLQSEILLSSPQHRYLLRVIRRTLQSSLDYLSEHVLHGEFRPVAVEVPFGEEMDGLPPVEVDLPGGGRVLLRGRIDRVDALEGRDGRWYVRVIDYKSGRRDLRLGDFYHGLTLQLLLYLMAVVEGGEPLLPGTRVPAGALYLPVYDPVEPVNAPVPPDEVRPLRRKRYQARGLVSDDPAVIQAMDAAGLGLIQAKLKKDGTVYKGAPVASPDQFRQLFAHLRRVVRACGEQILQGEAAIAPYRLGPHTACQYCAYRPVCQFDPAVEPQGYRRLEKMDAPDVWQRVAAAGGEGDV
What is the function of this protein?
The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease.  Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination.  The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity.
What are the official names of this protein?
ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease AddB, DNA 3'-5' helicase AddB.
What is the protein family that this protein belongs to?
Belongs to the helicase family. AddB/RexB type 1 subfamily.
Protein: MU111_SCHPO
Sequence: MLSKKMKICRPSLVLIYLWYLVDCTSFSMNSVTCLRLMQLLLAKYYQIPIDLVGEKLSIVSASSCLLQYLVALVVVPFYSTIIKKLTPWFTVFTTWVGEEYFFFASTLSILYMDDFPTCAYFVIFSISFLLGISGTGPSLNASYKSLCKLYSYENSFIVVLNSIFVVSSCIGPFLGSILLLRVSLLQLYLISWTIHFINFVFHSLLAVFFSSKYTSYAQKEGQPILNATENLEVEYNALNTTPSSFEEQPLLNGLNDSPRNPVSRTNAEGFKALNASFDGSYKFPIPIVLLCFFLYSLLTPFFDIHLQFQLIVMHMSIVQVGFINSVKTFGSLLTCSVCLFLTYVGGFSVHMMKTTMLIGLTATTLIIFILYFATAQTLPCLALFYGITSSIGPSIHGLVAAYVPNDKPHRYWKFTALLEASATFISYPFQSLAFIVCLKYCSFYFFIGPICICLLGSISSYLLLGYH
What is the function of this protein?
Has a role in meiosis.
What are the official names of this protein?
Meiotically up-regulated gene 111 protein.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: PYRH_JANMA
Sequence: MTTPAYKRVLLKLSGEALMGDDPYGINRATIERMVADVSEVAKLGVELAIVIGGGNIFRGVAPGAQGMDRATADYMGMLATVMNSLALADAMRQVGITARVMSAIAIEQVVEPYVRPKALQYLEEGKIVIFAAGTGNPFFTTDTAAALRGSEIGAEIVLKATKVDGVYSADPNKDPDATRYATITFDEAISKHLQVMDATAFALCRDQKLPIKVFSIVKPGALKRVVMGEDEGTLVHV
What is the function of this protein?
Catalyzes the reversible phosphorylation of UMP to UDP.
What are the official names of this protein?
Uridylate kinase, UK, Uridine monophosphate kinase, UMP kinase, UMPK.
What is the protein family that this protein belongs to?
Belongs to the UMP kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RR4_GLAMU
Sequence: RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKNKQRSKALIQNFIASSPHQEELPNHLTIDPFQYKGLVNQIIDSKWIGLKINELLVVEYYSRQT
What is the function of this protein?
With S5 and S12 plays an important role in translational accuracy.
What are the official names of this protein?
30S ribosomal protein S4, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS4 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: LRIG1_MOUSE
Sequence: MARPGPGVLGAPRLAPRLLLWLLLLLLQWPESAGAQAGPRAPCAAACTCAGDSLDCSGRGLATLPRDLPSWTRSLNLSYNRLSEIDSAAFEDLTNLQEVYLNSNELTAIPSLGAASIGVVSLFLQHNKILSVDGSQLKSYLSLEVLDLSSNNITEIRSSCFPNGLRIRELNLASNRISILESGAFDGLSRSLLTLRLSKNRITQLPVKAFKLPRLTQLDLNRNRIRLIEGLTFQGLDSLEVLRLQRNNISRLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNSISRIQRDGWSFCQKLHELILSFNNLTRLDEESLAELSSLSILRLSHNAISHIAEGAFKGLKSLRVLDLDHNEISGTIEDTSGAFTGLDNLSKLTLFGNKIKSVAKRAFSGLESLEHLNLGENAIRSVQFDAFAKMKNLKELYISSESFLCDCQLKWLPPWLMGRMLQAFVTATCAHPESLKGQSIFSVLPDSFVCDDFPKPQIITQPETTMAVVGKDIRFTCSAASSSSSPMTFAWKKDNEVLANADMENFAHVRAQDGEVMEYTTILHLRHVTFGHEGRYQCIITNHFGSTYSHKARLTVNVLPSFTKIPHDIAIRTGTTARLECAATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDMGVYSCTAQNSAGSVSANATLTVLETPSLAVPLEDRVVTVGETVAFQCKATGSPTPRITWLKGGRPLSLTERHHFTPGNQLLVVQNVMIDDAGRYTCEMSNPLGTERAHSQLSILPTPGCRKDGTTVGIFTIAVVCSIVLTSLVWVCIIYQTRKKSEEYSVTNTDETIVPPDVPSYLSSQGTLSDRQETVVRTEGGHQANGHIESNGVCLRDPSLFPEVDIHSTTCRQPKLCVGYTREPWKVTEKADRTAAPHTTAHSGSAVCSDCSTDTAYHPQPVPRDSGQPGTASSQELRQHDREYSPHHPYSGTADGSHTLSGGSLYPSNHDRILPSLKNKAASADGNGDSSWTLAKLHEADCIDLKPSPTLASGSPELMEDAISTEAQHLLVSNGHLPKACDSSPESVPLKGQITGKRRGPLLLAPRS
What is the function of this protein?
Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
What are the official names of this protein?
Leucine-rich repeats and immunoglobulin-like domains protein 1, LIG-1.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein.
Protein: Y193_SACS2
Sequence: MIQEELVQIQELNEEIGRLLIEIARKSIKEEFKLDKLDLSKYDNPILDKKGLAFVTLEKIAYNTSSLRGCIGYVEAVAPLKQIAASAAKAAAFSDPRFNPLQEDELANIIIEVTVLTKPEEIKVKDRWDLPKIIKVGEDGLIVEKGILHSGLLLPQVPMEYCWDEETFLAETCIKASLEPDCWLDSSVRIKRFHGIIFKETKPNGSDIIVIKPSDIKCKLNELINNL
What are the official names of this protein?
Protein SSO0193.
Protein: PDXK_SALPA
Sequence: MGQESDIQSVLFDDNHRALQTDIVAVQSQVVYGSVGNSIAVPAIKAQGLRVTAVPTVLFSNTPHYKTFYGGIIPAEWFAGYLTALNERDALRELKAITTGYMGSADQIVLLSKWLMAIRASHPEVCILVDPVIGDTDSGMYVQAEIPQAYRTYLLPQAQGLTPNVFELEMLSGKPCRTLEEAVAAAQSLLSDTLKWVVITSAPGESLETITVAVVTAQVVEVFAHPRVATELKGTGDLFCAELVSDIVQGKKLTTAAKDAAQRVLEVMTWTQQCGCDELILPPAGEAR
What is the function of this protein?
B6-vitamer kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP).  Catalyzes the phosphorylation of pyridoxine (PN), pyridoxal (PL), and pyridoxamine (PM), forming their respective 5'-phosphorylated esters, i. e.  PNP, PLP and PMP.
What are the official names of this protein?
Pyridoxine/pyridoxal/pyridoxamine kinase, PN/PL/PM kinase, B6-vitamer kinase.
What is the protein family that this protein belongs to?
Belongs to the pyridoxine kinase family. PdxK subfamily.
Protein: UBC14_ARATH
Sequence: MANNQASLLLQKQLKDLCKKPVDGFSAGLVDEKNVFQWSVSIMGPPDTLYEGGFFNAIMSFPENYPVSPPTVTFTSEMWHPNVYSDGKVCISILHPPGDDPHGYELASERWTPVHTVESIVLSIISMLSGPNDESPANVEAAKEWRDNRAEFRKKVSRCVRRSQEML
What is the function of this protein?
Accepts the ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins.  Involved in the formation of multiubiquitin chains.  Signal the protein for selective degradation.
What are the official names of this protein?
Ubiquitin-conjugating enzyme E2 14, E2 ubiquitin-conjugating enzyme 14, TAYO29, UbcAt3, Ubiquitin carrier protein 14, Ubiquitin-protein ligase 14.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-conjugating enzyme family.
Protein: PLOD3_RAT
Sequence: MAASVPEPRLLLLLLLLLPPLPPVTSASDRPRGANPVNPDKLLVITVATAETEGYRRFLQSAEFFNYTVRTLGLGQEWRGGDVARTVGGGQKVRWLKKEMEKYASQEDMIIMFVDSYDVILASSPTELLKKFVQSGSHLLFSAESFCWPDWGLAEQYPEVGVGKRFLNSGGFIGFAPTIHRIVRQWKYKDDDDDQLFYTQLYLDPGLREKLKLSLDHKSRIFQNLNGALDEVVLKFDQNRVRIRNVAYDTLPVVVHGNGPTKLQLNYLGNYVPNGWTPQGGCGFCNLNRRTLPGGQPPPRVLLAVFVEQPTPFLPRFLQRLLLLDYPPDRISLFLHNNEVYHEPHIADAWPQLQDHFSAVKLVGPEEALSSGEARDMAMDSCRQNPECEFYFSLDADAVLTNPETLRILIEQNRKVIAPMLSRHGKLWSNFWGALSPDEYYARSEDYVELVQRKRVGLWNVPYISQAYVIRGETLRTELPEKEVFSSSDTDPDMAFCRSVRDKGIFLHLSNQHEFGRLLSTSHYDTDHLHPDLWQIFDNPVDWREQYIHENYSRALDGEGLVEQPCPDVYWFPLLTEQMCDELVEEMEHYGQWSGGRHEDSRLAGGYENVPTVDIHMKQVGYEDQWLQLLRTYVGPMTEHLFPGYHTKTRAVMNFVVRYRPDEQPSLRPHHDSSTFTLNVALNHKGVDYEGGGCRFLRYDCRVSSPRKGWALLHPGRLTHYHEGLPTTRGTRYIMVSFVDP
What is the function of this protein?
Multifunctional enzyme that catalyzes a series of post-translational modifications on Lys residues in procollagen.  Plays a redundant role in catalyzing the formation of hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens (By similarity).  Plays a redundant role in catalyzing the transfer of galactose onto hydroxylysine groups, giving rise to galactosyl 5-hydroxylysine (By similarity).  Has an essential role by catalyzing the subsequent transfer of glucose moieties, giving rise to 1,2-glucosylgalactosyl-5-hydroxylysine residues.  Catalyzes hydroxylation and glycosylation of Lys residues in the MBL1 collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues.  Catalyzes hydroxylation and glycosylation of Lys residues in the ADIPOQ collagen-like domain, giving rise to hydroxylysine and 1,2-glucosylgalactosyl-5-hydroxylysine residues.  Essential for normal biosynthesis and secretion of type IV collagens.  Essential for normal formation of basement membranes (By similarity).
What are the official names of this protein?
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3.
What are the subcellular locations of this protein?
Rough endoplasmic reticulum. Endoplasmic reticulum lumen. Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. Secreted. Secreted, extracellular space. Note=The majority of the secreted protein is associated with the extracellular matrix.
Protein: ISPF_ORYSJ
Sequence: MATASSLFLASPVATAPTARARSTPSASPARPSLRLRRPSTLAAAAVQAEHQPAVAAAPKPPALPFRVGHGFDLHRLEPGLPLIIGGIDIPHDRGCDAHSDGDVLLHCVVDAILGALGLPDIGQIFPDSDPRWKGADSSVFMREAVKLMHEAGYELGNLDATLILQKPKISPFKETIRSNLCDLLGADPSVVNLKAKTHEKVDSLGENRSIAAHTVVLLMRK
What is the function of this protein?
Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate into 2C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP (Probable).  Is essential for chloroplast development (PubMed:29143298).
What are the official names of this protein?
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, chloroplastic, MECDP-synthase, MECPS, MECS.
What is the protein family that this protein belongs to?
Belongs to the IspF family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: F1712_MOUSE
Sequence: MPPPSGPGVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSGNGSWLELIPLAAVSVHLLTGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTSGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDNKRDQATSMSQLHLICGGPLEPTSSGDPEAPPPGSLHSAFSSSRDLASSRDDFFRAKPRSASRPAAEPPGARTVEGAGLKSARSVEGPGGLEPSLDEYRRGPAGAAAFLHEPPSPPPSFDHYLGHKGAAESKTPDFLLSQSVDQLARPPSLSQPGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDEATPPEGSAAGPARPFPQPDPQRPLMQGHAGAGGDSGGGEGWGGGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGSGGRSTDASLDSGVDVHEARPARRRLPREERERAQLPAPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVVAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK
What are the official names of this protein?
Protein FAM171A2.
What is the protein family that this protein belongs to?
Belongs to the FAM171 family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: PP451_ARATH
Sequence: MDASVVRFSQSPARVPPEFEPDMEKIKRRLLKYGVDPTPKILNNLRKKEIQKHNRRTKRETESEAEVYTEAQKQSMEEEARFQTLRREYKQFTRSISGKRGGDVGLMVGNPWEGIERVKLKELVSGVRREEVSAGELKKENLKELKKILEKDLRWVLDDDVDVEEFDLDKEFDPAKRWRNEGEAVRVLVDRLSGREINEKHWKFVRMMNQSGLQFTEDQMLKIVDRLGRKQSWKQASAVVHWVYSDKKRKHLRSRFVYTKLLSVLGFARRPQEALQIFNQMLGDRQLYPDMAAYHCIAVTLGQAGLLKELLKVIERMRQKPTKLTKNLRQKNWDPVLEPDLVVYNAILNACVPTLQWKAVSWVFVELRKNGLRPNGATYGLAMEVMLESGKFDRVHDFFRKMKSSGEAPKAITYKVLVRALWREGKIEEAVEAVRDMEQKGVIGTGSVYYELACCLCNNGRWCDAMLEVGRMKRLENCRPLEITFTGLIAASLNGGHVDDCMAIFQYMKDKCDPNIGTANMMLKVYGRNDMFSEAKELFEEIVSRKETHLVPNEYTYSFMLEASARSLQWEYFEHVYQTMVLSGYQMDQTKHASMLIEASRAGKWSLLEHAFDAVLEDGEIPHPLFFTELLCHATAKGDFQRAITLINTVALASFQISEEEWTDLFEEHQDWLTQDNLHKLSDHLIECDYVSEPTVSNLSKSLKSRCGSSSSSAQPLLAVDVTTQSQGEKPEEDLLLQDTTMEDDNSANGEAWEFTETELETLGLEELEIDDDEESSDSDSLSVYDILKEWEESSKKE
What is the function of this protein?
Involved in the regulation of early chloroplast development and chloroplast gene expression in a SIGF-dependent manner.
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At5g67570, chloroplastic, Protein DELAYED GREENING 1, Protein EMBRYO DEFECTIVE 1408.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: UBIA_LEGPL
Sequence: MIPWNAYVRLLRLNKPIGILLLWYPTAWALWMANQGFPSIDLLMIFLLGTVFMRSAGCVINDIADRHIDRHVARTQFRPLTSGEVSLSEAFILLFILLCASLFLLLKLPINCFYFAVISVLITFLYPFCKRFFNAPQLVLGLAFSMGIPMAFIASGKNLNSDFIVLFLINFSWIIAYDTMYAMTDKADDLKIGVKSTAIYFASYDRLIIALLLIFLHSLWLVWAINKNVECFFYLLWCTAAGILTYQLKLIYARIPKNCFKAFLVSGYYGLVMWFAVGLALI
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YURK_BACSU
Sequence: MLNNGSSTPLYIQLKQIITDDIKKGVYSPTAKLPTENELCTKYNVSRITVRKAILDLVEEGYLIRQQGKGTFVKSPKLKRELIAVNGYSEFMESTGKKPKHHVLSHDIIPASKPIAEKLQIQPESPVVELKRILYNDDQPLTFEVTHYPLDLFPGIDTFIADGVSMHDILKQQYKVVPTHNTKLLNVVYAQQEESKYLDCDIGDALFEIDKTAFTSNDQPIYCSLFLMHTNRVTFTINSPYT
What are the official names of this protein?
Uncharacterized HTH-type transcriptional regulator YurK.
Protein: KHSE_STAAC
Sequence: MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPNLCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGYYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRSLNSQVVSCHSELVDINISGVKERIVYQ
What is the function of this protein?
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
What are the official names of this protein?
Homoserine kinase, HK, HSK.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL22_RICM5
Sequence: MYMVQENKNFATAQAKSIRVSSRKLNLVAAFIRNMKVSEALVQLTFSPKRIAKVVKDCLQSAVANAENNLGLDIDRLVITKATVGKALVMKRVMPRAKGRATRINKFFSNLYITVTEKEDN
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: RL28_SALHS
Sequence: MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRIIDKKGIETVLSELRARGEKY
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: RS7_METBF
Sequence: MKIFGKWDPTEVEVRDLGIKRYVSLTPVIVPHSSGKHARQQFNKSEISIVERLANNLMRTEINTGKKQKTLRAVEEAFDIVSKKTKQNPIQVLVDAIANAGPREEVVRLKYGGISVPKAVDTAPQRRVDTALRYISMGTNNAAFKSKRSVAECLATELIGAANRDTKSFAINRKDAKERVAKAAR
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: RICKA_RICMO
Sequence: MTKEIDINKLLAQENNALNTILSQVNELCEQNKQLQGLIEIQNETKALEKEYNRSLPWFKRFVNTVSNVKYIFIKSEEQLTNEAIKYNNKILKDIDNKIYNIAEKSVSLKQELQEEIEKNFKDLTKKDLSKDQRERLSEVFFSYKSKPERFSALHMTNPLQFINAEELEKQYNSLNATKQNIQNLISENSNVKELKEIQKQVAEIREEVPYTFFEKLNNIWQNVKNVFVNNSEQVLAKNKESNTRTIRKIDEQLYKTKHKFEELIENKERNINDIIAKLPDNEELQKIVSNLTNHMASTKEPILTNSSLAKPLENNITPPPPLPGNNIPSPPPPPPPLPGNNIPSPPPPPPPLPGNNIPSPPPPPPPLPGNNIPSPPPPPPPLSGNNIPSPPPPPPPLSGNNIPSPPPPPPPLPGNNIPSPPPPPPPLSQNNIPPPPPPPMAPVSAQTEKLSKPVEATTVKKPENQPRPSIDTSDLMREIAGPKKLRKVEETDVKVQDSRDLLLQSIRGEHKLKKVEFDPNTGKPVAHSHSKPVQNVNKLSGVASILARRVVMEMSDSSGSESDSGNWSDVGVNRNTKTLKTKRERRKILNNRNSQKPSFVK
What is the function of this protein?
Recruits and activates the Arp2/3 complex, which in turn leads to actin polymerization, promoting Rickettsia motility during infection.
What are the official names of this protein?
Arp2/3 complex-activating protein rickA, Actin polymerization protein rickA.
What are the subcellular locations of this protein?
Cell surface.
Protein: RL11_HELPJ
Sequence: MAKKVVGEIKLQIPAGKANPSPPVGPALGQRGVNIMEFCKAFNERTKDMGSFNIPVIITVYQDKSFTFITKKPPVTDLIKKASGVEKGSDNPLKNKIAKLTHKQVEEIAQLKMEDLNTSTMEAAKKIVMGSARSMGVEVVD
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: RL22_BORGP
Sequence: MLSQIKREGNRVVMLVNRRYTARGKNLPSSPKKVRPIADNIRGKSYIKAIAVLCSMPNKGAKLLEKVVKSAASNAMYHNKNLSEDMIFVKIVMVDDGRRRKKIWPRARGRADRLVNRNCHIFVEVDEKKDIKG
What is the function of this protein?
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
What are the official names of this protein?
50S ribosomal protein L22.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL22 family.
Protein: CYB_PRIPR
Sequence: MTNIRKSHPLIKIINGSFIDLPTPSNISAWWNFGSLLGICLILQILTGLFLAMHYTSDTATAFSSVTHICRDVNYGWMIRYMHANGASMFFICLFMHVGRGMYYGSYTFLETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTSLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAAVHLLFLHETGSNNPSGITSDLDKIPFHPYYTIKDILGLLFLIQVLMLLVLFSPDMLGDPDNYIPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILAIIPLLHTSKQRGMMFRPLSQCLFWLLVADLLTLTWIGGQPVEYPFIIIGQLASVIYFSIILILMPISGIIENHLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: PGTB_SALTY
Sequence: MKGRLLQRLRQLSISNSLRGAFLTGALLTLIVSMVSLYSWHEQSSQVRYSLDEYFPRIHSAFLIEGNLNLAVDQLNEFLLAPNTTVRLQLRTQIIQHLDKIERLSQGLQLAERRQLAVILQDSRTLLAELDNALYNMFLVREKVSELSARIDWLHDDFTTELNSLVQDFTWQQGTLLDQIEANQGDAAQYLQRSREVQNEQQQVYTLARIENQIVDDLRDRLNELKSGNNDGMLVETHIRYLENLKKTADENIRALDDWPSTITLRQTIDELLEIGMVKNKMPDTMRDYVAAQKALLDASRAREATLGRFRTLLEAQLGSSHQQMQTFNQRLEQIVRVSGGLILVATLLALLLAWGLNHYFIRSRLVKRFTALNQAVVQIGLGRTDSTIPVYGRDELGRIARLLRHTLGQLNMQRRQLEQEVAERKEIEADLRAMQDELIQTAKLAVVGQTMTTLAHEINQPLNALSMYLFTAGRAIEQGQSGQARNTLTKAEGLINRIDAIIRSLRQFTRRAELETPLYPVDLRQTFVAAWELLAMRHQSRQGALSLPTDTVWVSGDEVRIQQVLVNVLANALDACSHDAVIAVTWQTQGEALEVYIADNGPGWPVALLPSLLKPFTTSKAVGLGIGLSISVSLMAQMKGDLRLASTLTRNACVVLQFSVTDVDDVE
What is the function of this protein?
Member of the two-component regulatory system PgtB/PgtA that regulates the inducible phosphoglycerate transport system.  Activates PgtA by phosphorylation.
What are the official names of this protein?
Phosphoglycerate transport system sensor protein PgtB.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PHOSP_IHNVO
Sequence: MSDGEGEQFFNLEGEDILRLESRLKNPRNDGQIGKNPRQRKEDQAPQEEPKKTTRRPDKNKGLSQLEQLILKYVEEESCQDALKDFGGLIANIRQAHQAELTSHLEKVATEHRANLQALTKSQQEHEKVSKEILSAVIAIRSNLNENHSPRPKPLDPDQVKAARALGFGIGYRTALNVFDRIKGVTPDNAGSQEVKNMAIRAAEEDEYEGSPTFFRKVIDAVKKRMKQGQ
What is the function of this protein?
Essential component of the RNA polymerase transcription and replication complex.  Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity).
What are the official names of this protein?
Phosphoprotein, Protein P, Protein M1.
What is the protein family that this protein belongs to?
Belongs to the novirhabdovirus protein P family.
What are the subcellular locations of this protein?
Host cytoplasm.