PharMolix/UniProtQA huggingface dataset:
Protein: RSXA_ECOLC
Sequence: MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
What is the function of this protein?
Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.  Required to maintain the reduced state of SoxR.
What are the official names of this protein?
Ion-translocating oxidoreductase complex subunit A, Rsx electron transport complex subunit A.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: OAZ_ONCVO
Sequence: MSKLAVSSSFSLLCGNCKRGHVGLECYSDVPTNNLLSNEHLHSLESFVNEVSSEWCCHLVDGNTLAIFLPFDQSTWNLSKGAFVSLLEFCEDNLPIKRILLCLNKINVDETVVSCFKYLGFSPLHPHLYPSCIDSQGVFVMVYSM
What is the function of this protein?
Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels.  Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.
What are the official names of this protein?
Ornithine decarboxylase antizyme, ODC-Az.
What is the protein family that this protein belongs to?
Belongs to the ODC antizyme family.
Protein: DCC_MOUSE
Sequence: MENSLGCVWVPKLAFVLFGASLLSAHLQVTGFQIKPFTSLHFVSEPSDAVTMRGGNVLLNCSAESDRGVPVIKWKKDGLILALGMDDRKQQLPNGSLLIQNILHSRHHKPDEGLYQCEASLADSGSIISRTAKVTVAGPLRFLSQTESITAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLNPLPGDSRVVVLPSGALQISRLQPGDSGVYRCSARNPASIRTGNEAEVRILSDPGLHRQLYFLQRPSNVIAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGTYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECAVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQSSAQLIVPKPAIPSSSILPSAPRDVLPVLVSSRFVRLSWRPPAEAKGNIQTFTVFFSREGDNRERALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEWGPGESSQPIKVATQPELQVPGPVENLHAVSTSPTSILITWEPPAYANGPVQGYRLFCTEVSTGKEQNIEVDGLSYKLEGLKKFTEYTLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNISLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSGPDVSTPMLPPVGVQAVALTHEAVRVSWADNSVPKNQKTSDVRLYTVRWRTSFSASAKYKSEDTTSLSYTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPRAVIVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETISGDRLTHQIMDLSLDTMYYFRIQARNVKGVGPLSDPILFRTLKVEHPDKMANDQGRHGDGGYWPVDTNLIDRSTLNEPPIGQMHPPHGSVTPQKNSNLLVITVVTVGVLTVLVVVIVAVICTRRSSAQQRKKRATHSVSKRKGSQKDLRPPDLWIHHEEMEMKNIEKPTGTDPAGRDSPIQSCQDLTPVSHSQSETQMGSKSASHSGQDTEDAGSSMSTLERSLAARRATRAKLMIPMEAQSSNPAVVSAIPVPTLESAQYPGILPSPTCGYPHPQFTLRPVPFPTLSVDRGFGAGRTQSVSEGPTTQQQPMLPPAQPEHPSSEEAPSRTIPTACVRPTHPLRSFANPLLPPPMSAIEPKVPYTPLLSQPGPTLPKTHVKTASLGLAGKARSPLLPVSVPTAPEVSEESHKPTEDPASVYEQDDLSEQMASLEGLMKQLNAITGSAF
What is the function of this protein?
Receptor for netrin required for axon guidance.  Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding.  Its association with UNC5 proteins may trigger signaling for axon repulsion.  It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.  Implicated as a tumor suppressor gene.
What are the official names of this protein?
Netrin receptor DCC, Tumor suppressor protein DCC.
What is the protein family that this protein belongs to?
Belongs to the immunoglobulin superfamily. DCC family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: UL14_HCMVM
Sequence: MGGGRLPPLWLPLLIAWSEWGNCCLDAPPVVRSPCLQPVRDRNRERNPGSPQLLPYGDRLEVACIFPAHDWPEVSIRVHLCYWPEIVRSLVVDARSGQVLHNDASCYIAGGRWRFEDGGAAQRLSLSFRLITETAGTYTCVLGNETHSLATETTALVADVHDLRHSDRSCDLAFGSRSQTRYLWTPDPSRLRSINCGWEGERHRVVHYIPGTSGLLPSCEEDERELCVPFISQSIADNNCSRRHRVDGARRRYHLRRDYWLTDPKIGLLAAGSVALTSLCHLLCYWCSESYRRLNTEEENEAAEETAAGEASAVAAAAVSEEEQQRE
What are the official names of this protein?
Uncharacterized protein UL14.
What is the protein family that this protein belongs to?
Belongs to the HHV-5 UL14 protein family.
What are the subcellular locations of this protein?
Host membrane; Single-pass membrane protein.
Protein: BACE_BACAM
Sequence: MKQLKPNSKYLLFGQALSFMGDYCVLPALLILSTYYHDYWVTSGVIAVRSIPMVFQPFLGVLVDRLDRVKIMLWTDVIRGVIFLGLTFLPKGEYPLLFLALLFVSYGSGVFFNPARLAVMSSLEADIKNINTLFAKATTISIIVGAAAGGLFLLGGSVELAVAFNGVTYLVSAFFISRIKLQYVPIQSENVREAFQSFKEGLKEIKTNAFVLNAMFTMITMALLWGVVYSYFPIVSRFLGDGEIGNFLLTFCIGFGGFIGAALVSKWGFNNNKGLMYFTVLSIVSLALFLFTPIFAVSVIAAILFFIAMEYGEVLAKVKVQENAANQIQGRIFSVAEASIGLCIAVGSMLINIVDAAVIMAFIVLLVSGLFLHTKLVNKSFSERNNESEQIHL
What is the function of this protein?
Part of the bacilysin biosynthesis operon.  May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic (By similarity).
What are the official names of this protein?
Putative bacilysin exporter BacE.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: VSP2_OVOOK
Sequence: VVGGDECNINEHRFLVALYY
What is the function of this protein?
Thrombin-like snake venom serine protease.  Releases both fibrinopeptides A and B from fibrinogen (FGA and FGB) to form fibrin clots.
What are the official names of this protein?
Thrombin-like enzyme okinaxobin-2, SVTLE, Fibrinogen-clotting enzyme, Okinaxobin II, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: SSPI_CALS4
Sequence: MDIKRAVLENLKRRSKEEIKGFIQEVVDSKNENAIPGLGVIFEAAWEKMTEEEKDSMMNLIMRGIS
What are the official names of this protein?
Small, acid-soluble spore protein I, SASP I.
What is the protein family that this protein belongs to?
Belongs to the SspI family.
What are the subcellular locations of this protein?
Spore core.
Protein: P2RY1_MELGA
Sequence: MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
What is the function of this protein?
Receptor for extracellular adenine nucleotides such as ADP (PubMed:8058061).  In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (By similarity).
What are the official names of this protein?
P2Y purinoceptor 1, P2Y1, 6H1 orphan receptor, ADP receptor, Purinergic receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RLMN_CAMLR
Sequence: MSELKNMLDFTKEELENLVQPKFRAKQIFEWVYKKYADDFLQMSSLPKDFRVYLQKNFHFSPLKCVKDEKSKDGSIKYLFELLDGKKIEAVLLPMKEELVDENGKIIKHARYTICVSSQVGCKSGCSFCLTAKGGLSRNLSAGEIVGQILWIKKHNKIPYERRVNIVYMGMGEPLDNLKNVSKAVKILADNDALAISPRRQTISTSGLAKQIKELGEMNLGVLLAISLHAVNDELRSELMPINKAYNIASIMEAVRNFPIDQRKRVMFEYLLIDGINDKIEHAKELVKLLNGIKAKVNLILFNPHEGSLYNRPSVENAIKFQDYLSAKGVTCTIRESKGLDISAACGQLKERQSKQ
What is the function of this protein?
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.  m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.
What are the official names of this protein?
Dual-specificity RNA methyltransferase RlmN, 23S rRNA (adenine(2503)-C(2))-methyltransferase, 23S rRNA m2A2503 methyltransferase, Ribosomal RNA large subunit methyltransferase N, tRNA (adenine(37)-C(2))-methyltransferase, tRNA m2A37 methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. RlmN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL23_ACIB5
Sequence: MNNERIYQVLKGPVFSEKAQVLGDTAGVQVFKVDINATKLEIKKAVEKLFGVEVVKVNTTITKGKTKRFGRTLGRRSDVKKAYVTLKAGQDVEMADLGDTAESAAE
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: RL7_GEOSE
Sequence: MTKEQIIEAVKNMTVLELNELVKAIEEEFGVTAAAPVVVAGGAAAGAEAAAEKTEFDVILADAGAQKIKVIKVVREITGLGLKEAKDLVDNTPKPIKEGIAKEEAEEIKAALEEAGAKVEIK
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.  Is thus essential for accurate translation (Probable).
What are the official names of this protein?
50S ribosomal protein L7/L12, BL13, Ribosomal protein 'A'.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL12 family.
Protein: EXC4_CAEEL
Sequence: MAEAYQIQSNGDPQSKPLLELYVKASGIDARRIGADLFCQEFWMELYALYEIGVARVEVKTVNVNSEAFKKNFLGAQPPIMIEEEKELTYTDNREIEGRIFHLAKEFNVPLFEKDPSAEKRIENLYRNFKLFLRAKVEFDKGKKEPSRVEDLPAQIKVHYNRVCEQLSNIDQLLSERKSRYLLGNSMTEYDCELMPRLHHIRIIGLSLLGFDIPHNFTHLWAYILTAYRTAAFIESCPADQDIIHHYKEQMNLFTNQRETLQSPTKTHTIPEKVLSDIRVKGLAPDVNVH
What is the function of this protein?
May insert into membranes and form chloride ion channels.  Involved in the formation of the excretory canal.  Required to prevent cystic lumenal expansions in the excretory cell.  Not required for formation of the initial tube, but is required for regulating the size of the tube lumen as it grows.
What are the official names of this protein?
Chloride intracellular channel exc-4, Excretory canal abnormal protein 4.
What is the protein family that this protein belongs to?
Belongs to the chloride channel CLIC family.
What are the subcellular locations of this protein?
Cytoplasm. Membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain. Localizes to various tubular membranes in distinct cell types, including the lumenal membrane of the excretory tubes.
Protein: NQRE_CELJU
Sequence: MEHLLSLLVRSVFIENMALAFFLGMCSFLAMSKKINAAIGLGIAVIVVQTVTVPANNLLLTYLLKEDALAWAGVTGVDLTFLSFISFIGVIAAIVQIMEMVMDKYMPALYNALGVFLPLITVNCVIMGGSLFMVERDYHFAESVVYGFGSGAGWAIAIVLLAGILEKMKYSDIPEGLRGLGITFITVGLMSLGFMSFGGISL
What is the function of this protein?
NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm.  NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.
What are the official names of this protein?
Na(+)-translocating NADH-quinone reductase subunit E, Na(+)-NQR subunit E, Na(+)-translocating NQR subunit E, NQR complex subunit E, NQR-1 subunit E.
What is the protein family that this protein belongs to?
Belongs to the NqrDE/RnfAE family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: SLE1_STAAU
Sequence: MQKKVIAAIIGTSAISAVAATQANAATTHTVKPGESVWAISNKYGISIAKLKSLNNLTSNLIFPNQVLKVSGSSNSTSNSSRPSTNSGGGSYYTVQAGDSLSLIASKYGTTYQNIMRLNGLNNFFIYPGQKLKVSGTASSSNAASNSSRPSTNSGGGSYYTVQAGDSLSLIASKYGTTYQKIMSLNGLNNFFIYPGQKLKVTGNASTNSGSATTTNRGYNTPVFSHQNLYTWGQCTYHVFNRRAEIGKGISTYWWNANNWDNAAAADGYTIDNRPTVGSIAQTDVGYYGHVMFVERVNNDGSILVSEMNYSAAPGILTYRTVPAYQVNNYRYIH
What is the function of this protein?
Peptidoglycan hydrolase involved in the splitting of the septum during cell division.  Binds to both alpha and beta-chains of human fibrinogen as well as fibronectin, which suggests a role in the colonization of host factor-coated material or host tissue.  Also exhibits lytic activity against S. carnosus and S. aureus cells but not against M. luteus cells.
What are the official names of this protein?
N-acetylmuramoyl-L-alanine amidase sle1.
What are the subcellular locations of this protein?
Secreted. Cell surface.
Protein: RL21_STAA8
Sequence: MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGDSVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: ENTS_ECO24
Sequence: MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVELRRFRQTPPQVTASDS
What is the function of this protein?
Component of an export pathway for enterobactin.
What are the official names of this protein?
Enterobactin exporter EntS.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. EntS (TC 2.A.1.38) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YR083_MIMIV
Sequence: MSTVKFTVVEPTIFSNVSISFKEDKIILFLESKVIGTLYQTSGNILWESECPITRSSYKELSHWMKCYDCGRDFCVPKNCDYHDQIPKSIYRESVLNKYTLTIKWTNYCSLESAITKTIQVYIDLNKIETNTN
What are the official names of this protein?
Uncharacterized protein R83.
What is the protein family that this protein belongs to?
Belongs to the mimivirus L15/L51/R83 family.
Protein: SH3P3_ARATH
Sequence: MDAFRRQASKLRDQVAKQQLAVIKQFSGTGYESSDVMVIDELEMQRHHQLDKLYRSTRSAKEFQRDIVKAAEAFTTIGLRHIEAGTKLSEDCCRYGNENSQNIDENILAKAAAIYGDARKHVDKEQEDFNKLLASQVLDPLRAMVAGSPLEDARHLAQRYSRMRQEAETHATEVSRRQARVREAPIPENVAKLQLAEAKMQELKANMAVLGKEATAALAAVESQQHRLTFQRLVAMVEGEKNYHLRIAAILSDIEAEMVTEKQHKESAPPAIPTENGSEKTSYFLAEVIHPFSAASEKELDLDKGDYIVVRKVSQTGWAEGECKGKAGWFPMAYIEKRQRLPTTNFAAEVY
What is the function of this protein?
May be involved in the recruitment of DRP2A to the accessory protein complex and in the negative regulation of its GTPase activity.
What are the official names of this protein?
SH3 domain-containing protein 3, AtSH3P3.
What are the subcellular locations of this protein?
Cytoplasmic vesicle, clathrin-coated vesicle.
Protein: PPAC_STRGC
Sequence: MSKILVFGHQNPDSDAIGSSYAFAYLAREAYGLDTEAVALGEPNEETAFVLDYFGVAAPRVITSAKAEGAEQVILTDHNEFQQSVADIAEVEVYGVVDHHRVANFETANPLYMRLEPVGSASSIVYRMFKEHSVAVSKEIAGLMLSGLISDTLLLKSPTTHPTDKAIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRVAQVNTVDIAEVLERQAEIEAAIEKAIADNGYSDFVLMITDIINSNSEILAIGSNMDKVEAAFNFVLENNHAFLAGAVSRKKQVVPQLTESFNA
What are the official names of this protein?
Probable manganese-dependent inorganic pyrophosphatase, Pyrophosphate phospho-hydrolase, PPase.
What is the protein family that this protein belongs to?
Belongs to the PPase class C family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADB_PSEF5
Sequence: MIYEGKAITVKALESGIVELNFDLKGESVNKFNRLTLNELRQAVDTIKADASIKGVIVSSGKDVFIVGADITEFVDNFKLPDAELVAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADYRVMAASAKIGLPEVKLGIYPGFGGTVRLPRLIGADNAIEWIAAGKENRAEDALKVGAVDAVVAPDKLKDAALALVKRAISGEFDYKAKRQPKLEKLKLNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKAANFGRDKALEVEAAGFVKLAKTSAAQSLIGLFLNDQELKKKAKAYDEIAKDVKQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDKGRMTAAKMAEVLNGIRPTLSYGDFGNVDLVVEAVVENPKVKQIVLAEVEGQVKEDTILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSELAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKIMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRRSAVDVLYEAKRLGQKNGKGFYAYETDKKGKQKKVADPSVLEVLKPIVYEQREVTDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPPFRGGALRYIDSIGVAEFVALADQYADLGALYHPTAKLREMAKNGQSFFG
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: Y2045_STRPI
Sequence: MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYIDYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFSEAYVNIWYKRYVELKNR
What are the official names of this protein?
UPF0374 protein SPH_2045.
What is the protein family that this protein belongs to?
Belongs to the UPF0374 family.
Protein: CAPR2_DANRE
Sequence: MRKTETMVQLSPSRTLETLTPSELTVEKDDGQGSPKPESPRMLSALQLALSSTTVYCGYEKYIEDGLICLKHKIRNIEKKKLKLERYSDKLKKGEKLNEDQLEAVGKYDEVVHNLKFAKELQKTIGSLTQDLLKAQRKAVRQEKQMKTDEEKSRLSLMLQVQYVLHSLQREDVRKNFCNTRQYSCYMSTQDMEGLMDLASLVGCKRDYSISLEDQMRRAAIVYWELLEGNEKPVAGSTYKHMKEKLLRLVDSGFFDNIPLPKSDSQEKTETIKPDSQSRPSGLTTLVKLSSNEVPSKEFLNRRYMPETDERRRGETASPRNWKEDFLAMKEREPPDSWEMEELADPPASSQSPIQKPWKGAAGLIPKTVDIVKRSTTDPKEKRQRKKAEQDSKSMPVAVEVFSSPSPLPKDPVQRRQQLETLMDQISGSFSFMQESLLDGESSPVNTQTKRCRPSPGSSTPIVQRELTKSPSDILPSSQRSTPLRILLSGEGKGCLSNGDRSINGSDLELHSEDKPRKQAEGFNSPPLYRRGSSISVSLENQSTVQAGRQMLCNGVSSSGSAQTFSTPPSRRSISAENPFHNIHSVFNVIGESSGMKADESGFSESIHRSFTSAKTSSVTTASTQTPPELNPPEEDLQIEGQYPLECAVSAGGPVFSSSHSRVGQSCYSRGAVRGGYDAYRVNVRSPGGSFMSQTHREPASALYMARENGYQQNFKRGAGTATQRSSAGWSDSSQVSSPDRDGAYPLDSGLSDTLSIPAMEVPMNPQGPHTLMPVHVYPLTQLRVAFSAARTANFAPGTLDQPIAFDLLHTNLGDMFDTGSGRFTCPATGAYVFIFHILKLAISVPLYINLMRNEEVMVSAYANDGAPDHETASNHAVLQLFQGDQVWLRLHRGAIYGSSWKYSTFSGFLLYQD
What is the function of this protein?
Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway.  Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling.  May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons.  Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation.  May be involved in apoptosis.
What are the official names of this protein?
Caprin-2, RNA granule protein 140.
What is the protein family that this protein belongs to?
Belongs to the caprin family.
What are the subcellular locations of this protein?
Cytoplasm. Cell membrane; Peripheral membrane protein.
Protein: PYRD_VIBVY
Sequence: MLYRLARAGFFQLDAEKAHDLAIQNFKRFTGTPIDLFYRQQLPNRPVECMGLTFRNPVGLAAGLDKNGECIEAFDAMGFGFVEIGTVTPRAQSGNDKPRLFRLVGAEGIINRMGFNNLGVDNLIENVKKAKYSCVLGINIGKNKDTPIEKGAEDYLICMEKVYEYAGYIAVNISSPNTPGLRTLQYGEALDELLVELKRKQAELEEKHGKYVPLALKIAPDLTDDEISQICQSLINNKIDGVIATNTTLDRTMVEGMKYAQEAGGLSGRPLQSRSTEVVRLLRKELQGNIPIIGVGGVDSYVAAKEKMLAGADLVQVYSGFIYHGPGLVRDIVKNL
What is the function of this protein?
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
What are the official names of this protein?
Dihydroorotate dehydrogenase (quinone), DHOdehase, DHOD, DHODase, Dihydroorotate oxidase.
What is the protein family that this protein belongs to?
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: LERL1_BOVIN
Sequence: MAGIKALISLSFGGAIGLMFLMLGCALPIYNQYWPLFVLFFYILSPIPYCIARRLVDDTDAMSNACKELAIFLTTGIVVSAFGLPIVFARANLIEWGACALVLTGNTVIFATILGFFLVFGSNDDFSWQQW
What is the function of this protein?
Negatively regulates growth hormone (GH) receptor cell surface expression in liver.  May play a role in liver resistance to GH during periods of reduced nutrient availability (By similarity).
What are the official names of this protein?
Leptin receptor overlapping transcript-like 1.
What is the protein family that this protein belongs to?
Belongs to the OB-RGRP/VPS55 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: DCTA_ECOK1
Sequence: MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLFGFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS
What is the function of this protein?
Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane.
What are the official names of this protein?
C4-dicarboxylate transport protein.
What is the protein family that this protein belongs to?
Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: YI41_SCHPO
Sequence: MSNPESLKKQVEPPGYNELFMVEDVCNVDLEQGLDLCKPEKVNKQSQRSRQSRQSLFTNTIKPQKDKMNIKTNKIKEFLNDLFTEFSKFHNSYYPDGRISTRSNFRWPLLIIWSIIIVFAVDKKFEVQKFLSIWINENRFYSEIWVPIAIYVCLLVLMLLSLIFFAEFAVLALRVTGVIIAVLGMIIAVLGMIIAALGATITGLLYFGHWALYKLVILSLGFKIVTPGDVCVSNTLPTHNGETALHSETTVGSDIEQIELQNMPTPVKK
What are the official names of this protein?
UPF0494 membrane protein C1348.01.
What is the protein family that this protein belongs to?
Belongs to the UPF0494 family.
What are the subcellular locations of this protein?
Vacuole membrane; Multi-pass membrane protein.
Protein: RS7_BUCBP
Sequence: MPRRRGIGHRKILSDPKFSSEMVAKLINIIMVDGKKSIAEEIVYQALTMLAKKIGKPELEVLELALENVRPTVEVKSRRVGGSTYQVPIEVRPVRRHALAMRWIVHSARKRIDKSMIIRLSNELSDAIENKGSAVKKREDVHRMAEANKAFAHYRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: NUOCD_BUCCC
Sequence: MILSLFKLFGKENFFIQDSYLESPILWIDSTILIQVIGFLKKNNTCSYEILFDLFGIDERTRKNVKSFPNADFTVSYYFFSISNNSDLILKVALLKEHLQLPTISSIFLNANWYEREIWDMFGIVFNNHPYLTRILMPKNWVGHPLRKDYSSHATEFDEFYFTKQKEDLAMESLKFCPKSWGLENNDSNNSEYMFLNFGPNHPSSHGAFRIVLQLHGEKIINCIPDIGYHHRGAEKIAERQTWHSYIPYTDRIEYLGGCVNEMPYILAVEKLAGIVVPEKVQVIRILLSELFRINSHLLFLSTFIQDIGSMSTVFLAFTDRQKIYDLIESITGARMHPAWFRIGGVAKDLPKNWNSLLKKFLIWMPKRLDYYVNIAIKNKILISRSKGIAAYGKKEALSWGITGAGLRATGVNFDVRKNRPYSGYQNFDFEVPIGNNISDAYTRVLLKIEEIRQSLKILNQCLLHMPLGSYKSDHPLSTPQKKNKSLFHIERMITHFLQMSWGPIIPSNESFQMIEATKGINSYYLISDGLTTSYRTRIRTPSFAHLQQIPSVIRGYVISDLIVYLGSIDFVMSDVDR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NADH-quinone oxidoreductase subunit C/D, NADH dehydrogenase I subunit C/D, NDH-1 subunit C/D.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the complex I 49 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.