PharMolix/UniProtQA huggingface dataset:
Protein: GUAA_PORG3
Sequence: MLEKLIILDFGSQTTQLIARRIRELNTYCEVYPYNKLPEDLSGVRGIILSGSPYSVYDSKAFRIELSELRGKLPLLGICYGAQSLVHQAGGKVEPCDSREYGRTHLTLRQPEDALLTGLQSGTTVWMSHGDTITSLPEGFEVIAGTEDVPNAAFRIRGEKTWGVQFHPEIYHSEEGTKLLGNFLDICGMKRDWTPASFIEATVQELRERLGDDKVILALSGGVDSSVVAVLLNKAIGRNLTCIFVDHGLLRKGEFERVLQDYEHLGLNVIGVNAKEKFFAALSGVTDPEQKRKIIGRGFIEVFDEEARKLKDIKWLGQGTIYPDVIESLSITGMVIKSHHNVGGLPERMNLRLVEPLRMLFKDEVRRVGLELGMMPHLIHRHPFPGPGLGIRILGEITEEKATILQNADDIYMSLMREWGLYDQVWQAGAILLPVRSVGVMGDERTYEYTVALRAVTSMDAMSADWVHLPYDFLAKVSNEIINKVRGVNRVVYDISSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: RL25_ENDTX
Sequence: MKEVILDAQARTVGSKGDLAFLRKSGKIPAIFYGKGIKPEAIAVSSKVFVSIMEANGANVIINLNFKDGKKAAIVKSLDRDFLTQHTIHIDFHAISLEDKIEVLVPVHIAGVADGVKNFGGVMEFIVREVKVEAIPRNIPQKISVDVKALRIGQGITVADLPELDGVKYVQDSSTLIVHVIAVAAVFEEEKPEAMAGGTATVVQPEVIISKGKKDKEDEEAEKGTSVASPTTATGGTKK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: FADB_SHIFL
Sequence: MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLIEGAMAILRQAINGDLDWKAKRQPKQEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA
What is the function of this protein?
Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle.  Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA.  It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate.
What are the official names of this protein?
Fatty acid oxidation complex subunit alpha.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
Protein: T184A_HUMAN
Sequence: MSNVSGILETAGVPLVSANWPQPSPPPAVPAGPQMDHMGNSSQGAPWLFLTSALARGVSGIFVWTALVLTCHQIYLHLRSYTVPQEQRYIIRLLLIVPIYAFDSWLSLLLLGDHQYYVYFDSVRDCYEAFVIYSFLSLCFQYLGGEGAIMAEIRGKPIKSSCLYGTCCLRGMTYSIGFLRFCKQATLQFCLVKPVMAVTTIILQAFGKYHDGDFNVRSGYLYVTLIYNASVSLALYALFLFYFTTRELLRPFQPVLKFLTIKAVIFLSFWQGLLLAILERCGVIPEVETSGGNKLGAGTLAAGYQNFIICVEMLFASVALRYAFPCQVYAEKKENSPAPPAPMQSISSGIRETVSPQDIVQDAIHNFSPAYQHYTQQATHEAPRPGTHPSGGSGGSRKSRSLEKRMLIPSEDL
What is the function of this protein?
Acts as a heparin receptor in vascular cells (By similarity).  May be involved in vesicle transport in exocrine cells and Sertoli cells (By similarity).
What are the official names of this protein?
Transmembrane protein 184A.
What is the protein family that this protein belongs to?
Belongs to the TMEM184 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Endosome. Cytoplasmic vesicle, secretory vesicle membrane.
Protein: TRYT_SHEEP
Sequence: MLHLLALALLLSLVSAAPAPGQALQRSGIIGGKEAPGSRWPWQVSLRVRDQYWRHQCGGSLIHPQWVLTAAHCIGPELQEPSDFRVQLREQHLYYQDRLLPISRVIPHPHYYMVENGADIALLQLEEPVSISRHVQPVTLPPASETFPPESQCWVTGWGDVDNGRPLPPPYPLKQVKVPIVENSVCDWKYHSGLSTDYSVPIVQEDNLCAGDGGRDSCQGDSGGPLVCKVNGTWLQAGVVSWGDGCAKPNRPGIYTRITSYLDWIHQYVPQEP
What is the function of this protein?
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.
What are the official names of this protein?
Tryptase-2.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Tryptase subfamily.
What are the subcellular locations of this protein?
Secreted. Note=Released from the secretory granules upon mast cell activation.
Protein: RECR_SALTY
Sequence: MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQDVCNICSNPRRQENGQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLASEKISELILATNPTVEGEATANYIAELCAEAGVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIIF
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: DCBD1_HUMAN
Sequence: MVPGARGGGALARAAGRGLLALLLAVSAPLRLQAEELGDGCGHLVTYQDSGTMTSKNYPGTYPNHTVCEKTITVPKGKRLILRLGDLDIESQTCASDYLLFTSSSDQYGPYCGSMTVPKELLLNTSEVTVRFESGSHISGRGFLLTYASSDHPDLITCLERASHYLKTEYSKFCPAGCRDVAGDISGNMVDGYRDTSLLCKAAIHAGIIADELGGQISVLQRKGISRYEGILANGVLSRDGSLSDKRFLFTSNGCSRSLSFEPDGQIRASSSWQSVNESGDQVHWSPGQARLQDQGPSWASGDSSNNHKPREWLEIDLGEKKKITGIRTTGSTQSNFNFYVKSFVMNFKNNNSKWKTYKGIVNNEEKVFQGNSNFRDPVQNNFIPPIVARYVRVVPQTWHQRIALKVELIGCQITQGNDSLVWRKTSQSTSVSTKKEDETITRPIPSEETSTGINITTVAIPLVLLVVLVFAGMGIFAAFRKKKKKGSPYGSAEAQKTDCWKQIKYPFARHQSAEFTISYDNEKEMTQKLDLITSDMADYQQPLMIGTGTVTRKGSTFRPMDTDAEEAGVSTDAGGHYDCPQRAGRHEYALPLAPPEPEYATPIVERHVLRAHTFSAQSGYRVPGPQPGHKHSLSSGGFSPVAGVGAQDGDYQRPHSAQPADRGYDRPKAVSALATESGHPDSQKPPTHPGTSDSYSAPRDCLTPLNQTAMTALL
What are the official names of this protein?
Discoidin, CUB and LCCL domain-containing protein 1.
Protein: RL31_AYWBP
Sequence: MKANIHPQFKTVEVSCATCGKQHPIGTTVNSIKIETCSNCHTFYTGVQTFVVKAGPVDKFNKRYGITQDQKVKKFPSNADNQKEPAEEQE
What is the function of this protein?
Binds the 23S rRNA.
What are the official names of this protein?
50S ribosomal protein L31.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
Protein: HEM1_GLAP5
Sequence: MTILALGINHKTASVSLREKVAFVEDKRQRAFEQIRDQSLAESVVILSTCNRTELYFHQPKIPPQEEHPDNIAWREQCFNWFAEIHQLDKEELSEAYYFKQNLEAARHLMSVACGLDSLILGEPQILGQVKQAYQESEEFYHSQGSGVSTNLSRLFQKTFATAKRVRSETEIGSSAVSVAYAACGLARQIFDDFTKLRFLLVGAGETIELVARHLINHGAKNIMIANRTHIRAEMLAVKLDIPMQILSLSALQIGLNQADVVICSTGSPDILITKEMVEQAQKQRRFDPMLLIDIAVPRDIDEKAGELDSIYAYSVDDLQNIIQQNIAQRQQAAEQAKEIVIEEAKDFFVWLKQQQSTNLIKHYRQNAEEIRLDLLEKALSALQQGQDCEKVLNELSYKLTNQLLHIPTQALQAMAKNSNVKGLQSFSKALKLEE
What is the function of this protein?
Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
What are the official names of this protein?
Glutamyl-tRNA reductase, GluTR.
What is the protein family that this protein belongs to?
Belongs to the glutamyl-tRNA reductase family.
Protein: RS13_CHLMU
Sequence: MPRIIGIDIPAKKKLKISLTYIYGIGPALSEEIIARLQLNPEARAAELTEEEVGRLNALLQSDYVVEGDLRRRVQSDIKRLITIHAYRGQRHRLSLPVRGQRTKTNSRTRKGKRKTVAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: RL4_AZOVD
Sequence: MQLNVNGAQAIEVSERTFGGEFNETLVHQAVVAYLAGGRQGSKQQKNRSDVSGGGKRPWRQKGTGRARAGTSRGPLWRGGGVTFAARPQNHDQKLNKKMYRAALRSILSELVRQERLVVVEDFAVDAPKTKSLVSKLGGLGLSDVLIVSDAVDQNLYLAARNLPHVDVRDVLGSDPVSLIAYDKVLITVPAVKKFEELLG
What is the function of this protein?
Forms part of the polypeptide exit tunnel.
What are the official names of this protein?
50S ribosomal protein L4.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL4 family.
Protein: HIS6_BLOPB
Sequence: MLAKRIIPCLDVGNNKVIKGIQFKDHKIVGDILELANRYAKSGADELVFYDITASPNDQVVNKRWISQIAKVINIPFCVAGGINTLKQAKQILASGADKISINSPALINPMLIQELADHLGTQCVVVSIDTWHNPQKKIYQVKCYTGDSTRAKITTWQTLDWVKKVQEYGAGEIVLNMMNQDGMKNGYDLDQLRNIRKHCQVPLIASGGAGTYQHFLEAFRDADVDGALAASVFHNQIIDIHKLKQFLNKEGIKIRLC
What is the function of this protein?
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate.  The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
What are the official names of this protein?
Imidazole glycerol phosphate synthase subunit HisF, IGP synthase cyclase subunit, IGP synthase subunit HisF, ImGP synthase subunit HisF, IGPS subunit HisF.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SYH_ALIFM
Sequence: MAKTIQAIRGMNDCLPTQSPLWQKVEGSVKRVISAYGYNEVRMPIVEQTHLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIENGLLYNQEQRLWYMGPMFRHERPQKGRYRQFHQVGVEVFGLNGPDVDAELIMMTARLWRELGIDQHVRLELNSIGSLEARANYRTALVAFLEQHLDVLDEDCKRRMHTNPMRVLDTKNPDVQAILGDAPKLSEYLDDDSKAHFSGLCELLDAAGIQYQVNERLVRGLDYYNRTVFEWITESLGAQGTVCGGGRYDGLVEQLGGKTTPAVGFAMGLERLVLLMETLELTDVRRSVDVYMVTAGEGTLMAGMKLAESLREQVPGLRVMCHFGGGNFKKQFKRADNAGAAVALILGETEVAEQTVNVKDLRNGEQVTLPQSDVFTKLAELI
What are the official names of this protein?
Histidine--tRNA ligase, Histidyl-tRNA synthetase, HisRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TM2D2_CAEEL
Sequence: MLHKILFLICLASFIPTIGSISGTKDVKSKNCDGSAGLTCTFPGDCRIGDTVKVNCTSRKGCPNPVSRNNVEAVCRFCWQLLPGDYDCEPATNCSTSSTKLLVTKCSAHSSVICMGQRNFYKRIPCNWSSGYSWTKTMILSVVLGGFGADRFYLGLWKSAIGKLFSFGGLGVWTLVDVVLIAVGYIKPYDGSMYI
What are the official names of this protein?
TM2 domain-containing protein C41D11.9.
What is the protein family that this protein belongs to?
Belongs to the TM2 family.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: NSP4_ROTHW
Sequence: MDKLADLNYTLSVITSMNDTLHSIIQDPGMAYFLYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVIKYCIVTIINTLLKLAGYKEQVTTKDEIEQQMDRIVKEMRRQLEMIDKLTTREIEQVELLKRIHDNLITRPVDVIDMSKEFNQKNIKTLDEWESGKNPYEPSEVTASM
What is the function of this protein?
The secreted form acts as an enterotoxin that causes phospholipase C-dependent elevation of the intracellular calcium concentration in host intestinal mucosa cells.  Increased concentration of intracellular calcium disrupts the cytoskeleton and the tight junctions, raising the paracellular permeability.  Potentiates chloride ion secretion through a calcium ion-dependent signaling pathway, inducing age-dependent diarrhea.  To perform this enterotoxigenic role in vivo, NSP4 is released from infected enterocytes in a soluble form capable of diffusing within the intestinal lumen and interacting with host plasma membrane receptors on neighboring epithelial cells such as integrins ITGA1/ITGB1 and ITGA2/ITGB1.
What are the official names of this protein?
Non-structural glycoprotein 4, NSP4, NCVP5, NS28.
What is the protein family that this protein belongs to?
Belongs to the rotavirus NSP4 family.
What are the subcellular locations of this protein?
Host rough endoplasmic reticulum membrane; Single-pass type III membrane protein. Host membrane, host caveola; Single-pass type III membrane protein. Secreted. Note=NSP4 localizes also in vesicular structures which contain autophagosomal markers and associate with viroplasms in virus- infected cells. Additionally, a soluble form of glycosylated NSP4 is secreted despite retention of its transmembrane domain.
Protein: PT1_STAES
Sequence: MSKLIKGIAASDGVAIAKAYLIVEPDLSYDSNEKVTDIESEVEKFNDAIEASKIELTKIRNNAEAQLGADKAAIFDAHLLVLDDPELIQPIQDKIRNDKVNAATGLDEVTTQFISIFESMDNEYMKERAADIRDVSKRVLAHILGVDLPNPSLINESAVIVGNDLTPSDTAQLNKEFVQGFVTNIGGRTSHSAIMSRSLEIAAVVGTKSITEEVKQGDMIIVDGMSGDVIIDPTEDELIAYQNKRERFFEDKKELQKLRDADTVTVDGVHAELAANIGTPDDLSGVIDNGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKKVLETMDGKRVVVRTLDIGGDKELPYLDLPKEMNPFLGYRAIRLCLAQPEIFRPQLRALLRASVYGKLNIMFPMVATIKEFRDAKSMLLEEKENLLREGYEVSDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDQTAVPLLLGLGLDEFSMSATSILKARRQINGLSKNEMAELANRAVECSTQEEVVDLVNQLAK
What is the function of this protein?
General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS).  This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
What are the official names of this protein?
Phosphoenolpyruvate-protein phosphotransferase, Phosphotransferase system, enzyme I.
What is the protein family that this protein belongs to?
Belongs to the PEP-utilizing enzyme family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: UBA1_RAT
Sequence: MSSSPLSKKRRVSGPDPKPGSNCSSAQSVLSEVSSVPTNGMAKNGSEADIDESLYSRQLYVLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLREEDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSGFQVVVLTNSPLEEQLRVGEFCHSRGIKLVVADTRGLFGQLFCDFGEEMVLTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARHGFETGDFVSFSEVQGMVQLNGCQPIEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKKISFKSLPASLAEPDFVMTDFAKYSRPAQLHIGFQALHQFCAQHNRPPRPRNEEDATELVTLAQAVNARSPPAVQQDNVDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPIMQWLYFDALECLPEDKEALTEDKCLPRQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGCELLKNFAMIGLGCGEGGEVVVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMNPYIQVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNVDARMYMDRRCVYYRKPLLESGTLGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPAENVNQYLTDSKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWGDCVTWACHHWHTQYCNNIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNTLHLDYVMAAANLFAQTYGLTGSQDRAAVASLLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLPGFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDISPADRHKSKLIAGKIIPAIATTTAAVVGLVCLELYKVVQGHQQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEVQGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVSRVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR
What is the function of this protein?
Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system.  Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP.  Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress.  Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites.
What are the official names of this protein?
Ubiquitin-like modifier-activating enzyme 1, Ubiquitin-activating enzyme E1.
What is the protein family that this protein belongs to?
Belongs to the ubiquitin-activating E1 family.
What are the subcellular locations of this protein?
Cytoplasm. Mitochondrion. Nucleus.
Protein: Y2298_MYCTO
Sequence: MKYLDVDGIGQVSRIGLGTWQFGSREWGYGDRYATGAARDIVKRARALGVTLFDTAEIYGLGKSERILGEALGDDRTEVVVASKVFPVAPFPAVIKNRERASARRLQLNRIPLYQIHQPNPVVPDSVIMPGMRDLLDSGDIGAAGVSNYSLARWRKADAALGRPVVSNQVHFSLAHPDALEDLVPFAELENRIVIAYSPLAQGLLGGKYGLENRPGGVRALNPLFGTENLRRIEPLLATLRAIAVDVDAKPAQVALAWLISLPGVVAIPGASSVEQLEFNVAAADIELSAQSRDALTDAARAFRPVSTGRFLTDMVREKVSRR
What are the official names of this protein?
Uncharacterized oxidoreductase MT2355.
What is the protein family that this protein belongs to?
Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily.
Protein: SDC2_MOUSE
Sequence: MQRAWILLTLGLMACVSAETRTELTSDKDMYLDNSSIEEASGVYPIDDDDYSSASGSGADEDIESPVLTTSQLIPRIPLTSAASPKVETMTLKTQSITPAQTESPEETDKEEVDISEAEEKLGPAIKSTDVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA
What is the function of this protein?
Cell surface proteoglycan which regulates dendritic arbor morphogenesis.
What are the official names of this protein?
Syndecan-2, SYND2, Fibroglycan, Heparan sulfate proteoglycan core protein, HSPG.
What is the protein family that this protein belongs to?
Belongs to the syndecan proteoglycan family.
What are the subcellular locations of this protein?
Membrane; Single-pass type I membrane protein.
Protein: BKRB1_MACFA
Sequence: MASWPPLQLQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICSFGLLGNLFVLLVFLLPRRRLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGIIKANLFISIFLVVAISQDRYCVLVHPMASRRRQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLPHEAWHFARIVELNILAFLLPLAAIIFFNYHILASLRGREEVSRTRCGGSKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFLAFTNSSLNPVIYVFAGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
What is the function of this protein?
This is a receptor for bradykinin.  Could be a factor in chronic pain and inflammation.
What are the official names of this protein?
B1 bradykinin receptor, B1R, BK-1 receptor.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Bradykinin receptor subfamily. BDKRB1 sub-subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL31_HALSA
Sequence: MSASEFDDRFVTVPLRDVTKVPSHERAGEAMNIIRQHLAKQFAVDEDAVRLDPSINDAVWSEGNNNPPRKLRVHAGSFAEDGETVVEADYEG
What are the official names of this protein?
50S ribosomal protein L31e.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein eL31 family.
Protein: SCTN1_SALTI
Sequence: MKTPRLLQYLAYPQKITGPIIEAELRDVAIGELCEIRRGWHQKQVVARAQVVGLQRERTVLSLIGNAQGLSRDVVLYPTGRALSAWVGYSVLGAVLDPTGKIVERFTPEVAPISEERVIDVAPPSYASRVGVREPLITGVRAIDGLLTCGVGQRMGIFASAGCGKTMLMHMLIEQTEADVFVIGLIGERGREVTEFVDMLRASHKKEKCVLVFATSDFPSVDRCNAAQLATTVAEYFRDQGKRVVLFIDSMTRYARALRDVALASGERPARRGYPASVFDNLPRLLERPGATSEGSITAFYTVLLESEEEADPMADEIRSILDGHLYLSRKLAGQGHYPAIDVLKSVSRVFGQVTTPTHAEQASAVRKLMTRLEELQLFIDLGEYRPGENIDNDRAMQMRDSLKAWLCQPVAQYSSFDDTLSGMNAFADQN
What is the function of this protein?
ATPase component of the type III secretion system (T3SS), also called injectisome, which is used to inject bacterial effector proteins into eukaryotic host cells (By similarity).  Acts as a molecular motor to provide the energy that is required for the export of proteins (By similarity).  Required for type III secretion apparatus (T3SA) formation, proper protein secretion, host cell invasion and virulence (By similarity).  May play a critical role in T3SS substrate recognition, disassembly of the effector/chaperone complex and unfolding of the effector in an ATP-dependent manner prior to secretion (By similarity).
What are the official names of this protein?
SPI-1 type 3 secretion system ATPase, T3SS-1 ATPase, Invasion protein InvC.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FRDC_PHOLL
Sequence: MTTKRKPYIRSMAPNWWQKLGFYRFYILRESTAVTTMWFSILLIYGLFALKGGTQSWHEFVTFLQNPVILLVNIITLLGALLHTKTWFELAPKAANIVIKGEKMGSGPVIKLLWAVTIIVTMIILGIALL
What is the function of this protein?
Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; fumarate reductase is used in anaerobic growth, and succinate dehydrogenase is used in aerobic growth.  Anchors the catalytic components of the fumarate reductase complex to the cell inner membrane, binds quinones.
What are the official names of this protein?
Fumarate reductase subunit C, Fumarate reductase 15 kDa hydrophobic protein, Quinol-fumarate reductase subunit C, QFR subunit C.
What is the protein family that this protein belongs to?
Belongs to the FrdC family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PYRB1_SHEHH
Sequence: MSNPLYNKNIISITDLSRAELELIVSTANELKQHPRPDLLKNKVIASCFFEASTRTRLSFETAVQRLGGSVIGFPDSGNTSLGKKGETLADSVQVISSYSDAFFMRHNQEGAARLASEFSSVPVINGGDGSNQHPTQTLLDLFSIYETQGTLDKLQVAFVGDLKYGRTVHSLTQALSLFDCEFHFVAPPALSMPEYIIDELKEKGCTFTQYDSLDGVLSKLDILYMTRVQKERFDETEYQHMKSSFILTAQMFEGVKDNLKVLHPLPRVDEITTDVDSTPYAYYFQQAKNGVYARQALLALVLTNEFGDK
What are the official names of this protein?
Aspartate carbamoyltransferase 1, Aspartate transcarbamylase 1, ATCase 1.
What is the protein family that this protein belongs to?
Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
Protein: DTD_ECO27
Sequence: MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
What is the function of this protein?
An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs.  Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS.  Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site.  By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
What are the official names of this protein?
D-aminoacyl-tRNA deacylase, DTD, Gly-tRNA(Ala) deacylase.
What is the protein family that this protein belongs to?
Belongs to the DTD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DMDA_EUBBA
Sequence: MGMTMTQKILAAHASLDSVKAGDLIMADLDMVLANDITGPVAINVFGTIDKEKVFDKDKIALVPDHFAPAKDIKSAQQCKQVRCFACDQEITNYFEIGEMGIEHALLPEKGLVAAGDVVIGADSHTCTYGALGAFSTGVGSTDMAVGMATGKAWFKVPAALRFNLTGTLNKNVSGKDLILHIIGMIGVDGALYRSMEFTGPGVACLSMDDRFTISNMAIEAGGKNGIFPVDDQTISYMEEHGSGDYKVYAADADAVYEKTFDIDLSQLKSTVAFPHLPENTKTVDAIEEPVTIDQVVIGSCTNGRFEDLKRAADILRGKHVKKGVRMLVIPATHKIYLDAMEAGYLREFIEAGATISTPTCGPCLGGYMGILAEGERCVSTTNRNFVGRMGHVDSEVYLASPEVAAASAILGRIATPDEL
What are the official names of this protein?
2,3-dimethylmalate dehydratase large subunit.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.
Protein: OADC_PSEU2
Sequence: MPKASHQDLRRSFRALTSSNACFHTASVFDPMSARIAADLGFEVGILGGSVASLQVLAAPDFALITLSEFVEQATRIGRVAQLPVIADADHGYGNALNVMRTVVELERAGISALTIEDTLLPAQFGRKSTDLISTAEGVGKIRAALEARVDPEMSIFARTNAAIIPVQEAISRVQQYQAAGADGITIVGIRDFDHLAQISEGVTVPLMLVTYGNPELHDNARLAEMGVRVCVHGHAAYFAAIKATYDCLREQRQILGNESNMSATELTHTYTQPEDYVEWARKFMNVNE
What is the function of this protein?
Catalyzes the decarboxylation of oxaloacetate into pyruvate.  Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate.
What are the official names of this protein?
Oxaloacetate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
Protein: TRMFO_PROM2
Sequence: MIDKKVIVIGAGLAGSEAAWQVANAGVPVKLVEMRPFKSTPAHHTGEFGELVCSNSFGALNPDRAAGLLQKELRIFKSLIIQTADKFAVPAGGALAVDRSKFSMALTEALSSHPLIEIERFEQLDLPRKEKITILATGPLTSDELSYKIQAFTGIDACHFFDAASPIIYGDSIDQEIVFKASRYDKGDPAYLNCPMDKNNYIHFRNQLIEGEQANLKDFEKESANFFEACLPIEEIARRGVDTMRFGPLKSIGLWNPKWGDLFDRENRLKKRPYAIVQLRKEDLEGKLLNMVGFQTNLKWSEQKRIFRMIPGLEKAEFVRFGVMHRNTFLESPNLLLPTLQFMKRNNLFAAGQITGTEGYAAAAAGGLLAGINASLLAKGKKTVSFPKESMIGSLINFISNKNQILSNQKKNKFQPMPASFGLVPELTKRIKDKRLRYKAYQERSTEALNDFKNKLDYCFEKDHLLSKIY
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y540_METJA
Sequence: MEEIIDVKNPKEVIEYLNNIDVDEYVEIYFGRVHVEGRLMHYNDGLIRLVHEKYGIIEVEIEKILDDLLELVHSNGEKRVVLRFY
What are the official names of this protein?
Uncharacterized protein MJ0540.