PharMolix/UniProtQA huggingface dataset:
Protein: RUVC_POLAQ
Sequence: MRWIGIDPGLRITGFGVIDVDGQKLTYVASGTIESGDPAKGLPERLGALYAGVKEVLETYRPEQAAIEEVFLNVNPRSTLMLGQARGAVIAALVSEKLPVAEYSALRVKQAIVGTGRAAKPQVQEMVKRLLRLSRAPGTDASDALGVAICAAHHSQIPKAITSALASKKRSK
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair.  Endonuclease that resolves HJ intermediates.  Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction.  The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'.  Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange.  HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Crossover junction endodeoxyribonuclease RuvC, Holliday junction nuclease RuvC, Holliday junction resolvase RuvC.
What is the protein family that this protein belongs to?
Belongs to the RuvC family.
Protein: HBM_HUMAN
Sequence: MLSAQERAQIAQVWDLIAGHEAQFGAELLLRLFTVYPSTKVYFPHLSACQDATQLLSHGQRMLAAVGAAVQHVDNLRAALSPLADLHALVLRVDPANFPLLIQCFHVVLASHLQDEFTVQMQAAWDKFLTGVAVVLTEKYR
What are the official names of this protein?
Hemoglobin subunit mu, Hemoglobin mu chain, Mu-globin.
What is the protein family that this protein belongs to?
Belongs to the globin family.
Protein: RS3_HAHCH
Sequence: MGQKVNPVGIRLGIVKDHNSVWYADKKNYSDHLLTDIKVREFLMKKLEKASVSKVIIERPPQNAKITIHTARPGIVIGKKGEDVDRLRQEVGELMKVPVHINIEEIRKPDLDAKLVASGVAGQLERRVMFRRAMKRAVQNAMRQGAKGIKIQVGGRLGGAEIARTEWYREGRVPLHTLRADIDYATHEAHTTYGVIGVKVWIFKGEILGGIEQVRAEKKAAKKKSSK
What is the function of this protein?
Binds the lower part of the 30S subunit head.  Binds mRNA in the 70S ribosome, positioning it for translation.
What are the official names of this protein?
30S ribosomal protein S3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS3 family.
Protein: ABCF2_HUMAN
Sequence: MPSDLAKKKAAKKKEAAKARQRPRKGHEENGDVVTEPQVAEKNEANGRETTEVDLLTKELEDFEMKKAAARAVTGVLASHPNSTDVHIINLSLTFHGQELLSDTKLELNSGRRYGLIGLNGIGKSMLLSAIGKREVPIPEHIDIYHLTREMPPSDKTPLHCVMEVDTERAMLEKEAERLAHEDAECEKLMELYERLEELDADKAEMRASRILHGLGFTPAMQRKKLKDFSGGWRMRVALARALFIRPFMLLLDEPTNHLDLDACVWLEEELKTFKRILVLVSHSQDFLNGVCTNIIHMHNKKLKYYTGNYDQYVKTRLELEENQMKRFHWEQDQIAHMKNYIARFGHGSAKLARQAQSKEKTLQKMMASGLTERVVSDKTLSFYFPPCGKIPPPVIMVQNVSFKYTKDGPCIYNNLEFGIDLDTRVALVGPNGAGKSTLLKLLTGELLPTDGMIRKHSHVKIGRYHQHLQEQLDLDLSPLEYMMKCYPEIKEKEEMRKIIGRYGLTGKQQVSPIRNLSDGQKCRVCLAWLAWQNPHMLFLDEPTNHLDIETIDALADAINEFEGGMMLVSHDFRLIQQVAQEIWVCEKQTITKWPGDILAYKEHLKSKLVDEEPQLTKRTHNV
What are the official names of this protein?
ATP-binding cassette sub-family F member 2, Iron-inhibited ABC transporter 2.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
Protein: RFT1_CANGA
Sequence: MSGADILEKTTRGATFLMMGQLFSKIVTFLLNNTLVRYLSPRIFGITAFLEFIVGTVLFFSREAIRLSTQRIADGNDADNDHDHDRDDSALQVCVNFAMIPLFIGIPLSIGLIAWQYHNINGYFVTLPFFQWSVFAIWVGIILELVNEPLFVLNQHFLNYGARSRYESIAVTANCLVNFTVVYSYEKKLILTSYFDDSERFREGIAILAFALGKLAYAATLLMCYYYNYLMNFKSNKPFKLSLQKIKSKVNEKQTYYFRSDILEHFKKVYFQLCFKHLLTEGDKLIINTFCTVEEQGIYSLLSNYGSLITRLLFAPIEESLRLLLAVLLSKKDSKNLQLSMKVLVNLTKFYLYLSLLVMIFGPNNSSYLLQFLIGSKWSTNSVLHAIRVYCVYIPFLSFNGIFEAFLASVATGDQILRHSYFMMMCSFAFLINSWIFIEYLDLSVNGLIISNIINMSLRIIYSFSFIVKFYRELHTESSIFMNFTNFKATLGAAALVAILNWQMVGYVSSFNGFITSATLALILLSVILIKERATLNELIINRRAANMKSV
What is the function of this protein?
May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
What are the official names of this protein?
Oligosaccharide translocation protein RFT1.
What is the protein family that this protein belongs to?
Belongs to the RFT1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: EFTS_HELPH
Sequence: MSGISAQLVKKLRDLTDAGMMDCKKALVEVAGDLQKAIDFLREKGLSKAAKKADRIAAEGVIALEVAPDFKSAMMVEINSETDFVAKNEGFKELVKKTLETIKAHNIHATEELLKSPLDNKPFEEYLHSQIAVIGENILVRKIAHLKAPSSHIINGYAHSNARVGVLIGIKYDNEKNAPKVVELARNIAMHAAAMKPQVLDCKDFSLDFVKKETLALIAEIEKDNEEAKRLGKPLKNIPTFGSRIELSDEVLAHQKKAFEDELKAQGKPEKIWDKIVPGKMERFIADNTLIDQRLTLLGQFYVMDDKKTIAQVVADCSKEWDDDLKITEYVRFELGEGIEKKAENFAEEVALQMK
What is the function of this protein?
Associates with the EF-Tu. GDP complex and induces the exchange of GDP to GTP.  It remains bound to the aminoacyl-tRNA. EF-Tu. GTP complex up to the GTP hydrolysis stage on the ribosome.
What are the official names of this protein?
Elongation factor Ts, EF-Ts.
What is the protein family that this protein belongs to?
Belongs to the EF-Ts family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURQ_METM5
Sequence: MVPKVLVMSGYGINCETETAHAFQKAGAETDIVHINDLIAGKKKMADYEIIMFPGGFSYGDDTGSGNAFANKIKNNLFDDLKEFINSGKLILGICNGFQVMTNLGLFALPSTDYGERISALEANTNNRYECRWVHVKENDSICVFTKGITITHVPIAHGEGRFYCDEKTYFELKENKQIVFSYCDSEGNSANQEYPLNPNGAYYDIAGICDKTGRIMGLMPHPERSLYSISEPEYQLKKEIAKRNREIIPEFIESNLQIFKNAVEYFNK
What is the function of this protein?
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway.  Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.  The FGAM synthase complex is composed of three subunits.  PurQ produces an ammonia molecule by converting glutamine to glutamate.  PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner.  PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.
What are the official names of this protein?
Phosphoribosylformylglycinamidine synthase subunit PurQ, FGAM synthase, Formylglycinamide ribonucleotide amidotransferase subunit I, FGAR amidotransferase I, FGAR-AT I, Glutaminase PurQ, Phosphoribosylformylglycinamidine synthase subunit I.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: GATC_HELPJ
Sequence: MQIDDALLQRLEKLSMLEIKDEHKESVKGHLAEVLGFVENIFALETNNLKTDTHLSTPLREDEPKSQPHIAKEILSQNKHSQDHYFVVPKIIE
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Glutamyl-tRNA(Gln) amidotransferase subunit C, Glu-ADT subunit C.
What is the protein family that this protein belongs to?
Belongs to the GatC family.
Protein: BARD1_HUMAN
Sequence: MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS
What is the function of this protein?
E3 ubiquitin-protein ligase.  The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability.  Plays a central role in the control of the cell cycle in response to DNA damage.  Acts by mediating ubiquitin E3 ligase activity that is required for its tumor suppressor function.  Also forms a heterodimer with CSTF1/CSTF-50 to modulate mRNA processing and RNAP II stability by inhibiting pre-mRNA 3' cleavage.
What are the official names of this protein?
BRCA1-associated RING domain protein 1, BARD-1, RING-type E3 ubiquitin transferase BARD1.
What are the subcellular locations of this protein?
Nucleus. Note=During S phase of the cell cycle, colocalizes with BRCA1 into discrete subnuclear foci. Can translocate to the cytoplasm. Localizes at sites of DNA damage at double-strand breaks (DSBs); recruitment to DNA damage sites is mediated by the BRCA1-A complex.
Protein: EF1A4_ARATH
Sequence: MGKEKFHINIVVIGHVDSGKSTTTGHLIYKLGGIDKRVIERFEKEAAEMNKRSFKYAWVLDKLKAERERGITIDIALWKFETTKYYCTVIDAPGHRDFIKNMITGTSQADCAVLIIDSTTGGFEAGISKDGQTREHALLAFTLGVKQMICCCNKMDATTPKYSKARYDEIIKEVSSYLKKVGYNPDKIPFVPISGFEGDNMIERSTNLDWYKGPTLLEALDQINEPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGMIKPGMVVTFAPTGLTTEVKSVEMHHESLLEALPGDNVGFNVKNVAVKDLKRGYVASNSKDDPAKGAANFTSQVIIMNHPGQIGNGYAPVLDCHTSHIAVKFSEILTKIDRRSGKEIEKEPKFLKNGDAGMVKMTPTKPMVVETFSEYPPLGRFAVRDMRQTVAVGVIKSVDKKDPTGAKVTKAAVKKGAK
What is the function of this protein?
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.
What are the official names of this protein?
Elongation factor 1-alpha 4, EF-1-alpha 4, eEF-1A4.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region.
Protein: IL18_FELCA
Sequence: MAAIPVDDCINFVGMKFIDNTLYFVADSDENLETDYFGKLEHKLSILRNLNDQVLFINQGDQPVFEDMPDSDCTDNAPRTEFIIYMYKDSLTRGLAVTISVNYKTMSTLSCENKIISFKEMSPPESINDEGNDIIFFQRSVPGHDDKIQFESSLYKGYFLACEKEKDLFKLILKKKDENGDKSIMFTVQNKN
What is the function of this protein?
Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses.  Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators.  Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.  Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
What are the official names of this protein?
Interleukin-18, IL-18, Interferon gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma.
What is the protein family that this protein belongs to?
Belongs to the IL-1 family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Note=The precursor is cytosolic. In response to inflammasome-activating signals, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation. The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10.
Protein: PETG_MANES
Sequence: MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL
What is the function of this protein?
Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.  PetG is required for either the stability or assembly of the cytochrome b6-f complex.
What are the official names of this protein?
Cytochrome b6-f complex subunit 5, Cytochrome b6-f complex subunit PetG, Cytochrome b6-f complex subunit V.
What is the protein family that this protein belongs to?
Belongs to the PetG family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: PDRP_BACCN
Sequence: MDNKIVYVVSDSVGETADLVVRAAMGQFPFAPDIRRVPYVEDTGTLKEVISIAKSNRALICFTLVKPDMRQYLLTEAAKEGVEAYDIIGPLIDQIAEITRQVPRYEPGIVRKLDEEYFKKIEAIEFAVKYDDGRDARGILKADIVLIGVSRTSKTPLSQYLAHNKRLKVANVPLVPEVDPPEELYQVSKEKCFGLKINPEKLNHIRKERLKSLGLSDGATYANINRIKEEIDHFEKVINKINCQVIDVSNKAIEETANIIVNAVQNQRMF
What is the function of this protein?
Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
What are the official names of this protein?
Putative pyruvate, phosphate dikinase regulatory protein, PPDK regulatory protein.
What is the protein family that this protein belongs to?
Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.
Protein: RS16_BRUA2
Sequence: MALKIRLARAGSKKRPYYHVVVADVRAPRDGRFIETVGSWNPVLPKDAERVKLDAERIQHWIAQGAQPTDRVLRFLDQAGIAKRPSRNNPTKGEPGKKAQERLALAKQAEEEASAKAAEAAAAAAAPAEEAASE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: MTNA_ARTOC
Sequence: MSLQSIRYKRGMLQVLDQLQVPHVERYIPVSTAKEGWHVIKEMHVRGAPAIAIVAVLSLSIELTELMDHEKLSTEADEVEAYILEKLDYLVTSRPTAVNLSDAAIKLKTLVQKRKQIGDPKGKDLAEAYVEAAEKMLIDDAMDNHRLGDFGATWIVNNTPVGKEGKKVGVLTHCNTGSLATAGYGTALGVIRSLLASDKLEHAYCTETRPYNQGARLTAFELVHDKIPATLITDSMAASLLAQKGAGLAAIVVGADRVVANGDTANKIGTYQLAVLAKYHGVKFIVAAPRTTIDLRTKEGEDIIIEERAKSEVTRITGPRISDLGKNEENITLETVNIAAPGIDVWNPAFDVTPYDLIDAIVTEVGVAEKNADGLFQLEKLFGFP
What is the function of this protein?
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
What are the official names of this protein?
Methylthioribose-1-phosphate isomerase, M1Pi, MTR-1-P isomerase, S-methyl-5-thioribose-1-phosphate isomerase, Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein.
What is the protein family that this protein belongs to?
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: ATPA_CHLPB
Sequence: MSTTVRPDEVSAILRKHLAGFESEADVYDVGTVLQVGDGIARIYGLSKVAAGELLEFPDNVMGMALNLEEDNVGAVMFGKSTAVKEGDTVKRTGILASIPVGEAMLGRVINPLGEPIDGKGPIETSIRLPLERKAPGVIFRKSVNQPLQTGLKAIDAMIPIGRGQRELIIGDRQTGKTAVAIDTIINQKGKDVFCIYVAIGQKGSTIAQVVSTLEKYGAMEYTTVIASSASDPAPMQFIAPYAGAAIGEFFRDTGRHALVIYDDLSKQAVAYRQLSLLLRRPPGREAYPGDVFYLHSRLLERAAKITDDLETAKKMNDLPEPLKPMVKAGGSLTALPVIETQAGDVSAYIPTNVISITDGQIFLEPNLFNAGQRPAINVGISVSRVGGSAQIKAMKKITGTLRLDLAQFRELEAFSKFGSDLDKATKAQLDRGARLVEILKQDQYVPMAVEKQVAIIFAGTQGVLDQLDLQYIRRFEEEFLSLLEHKHSDILNSIAETGQMDVDVAKRLKEVAEQFMSTFKQKVTA
What is the function of this protein?
Produces ATP from ADP in the presence of a proton gradient across the membrane.  The alpha chain is a regulatory subunit.
What are the official names of this protein?
ATP synthase subunit alpha, ATP synthase F1 sector subunit alpha, F-ATPase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the ATPase alpha/beta chains family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: NUDT7_MOUSE
Sequence: MSRPCGLPEPVRNNLIDDAKARLRKSDVGTRYSHLSSNKFSVLVPLLARGGKLYLMFTVRSDKLKREPGEVCFPGGKRDPVDTDDTATALREAQEEVGLHPHQVEVVSHLVPYVFDNDALVTPVVGFLDHNFQAQPNADEVKEVFFVPLDYFLHPQVYYQKQITQSGRDFIMHCFEYKDPETGVNYLIQGMTSKLAVLVALIILEQSPAFKIDFDLHDLIPSCERTFLWRYSLSKL
What is the function of this protein?
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate (PubMed:11415433, PubMed:18799520, PubMed:29378847).  Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies (PubMed:11415433).  Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs (PubMed:18799520).  Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester (PubMed:18799520).  May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand (PubMed:18799520).  Does not play a role in U8 snoRNA decapping activity (PubMed:21070968).  Binds U8 snoRNA (PubMed:21070968).  Exhibits decapping activity towards dpCoA-capped RNAs in vitro (PubMed:32432673).
What are the official names of this protein?
Peroxisomal coenzyme A diphosphatase NUDT7, Nucleoside diphosphate-linked moiety X motif 7, Nudix motif 7.
What is the protein family that this protein belongs to?
Belongs to the Nudix hydrolase family. PCD1 subfamily.
Protein: HSP1_TACAC
Sequence: MARFRPSRSRSRSLYRRRRRSRRQRSRRGGRQTGPRKITRRGRGRGKSRRRRGRRSMRSSRRRRRRRRN
What is the function of this protein?
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis.  They compact sperm DNA into a highly condensed, stable and inactive complex.
What are the official names of this protein?
Sperm protamine P1.
What is the protein family that this protein belongs to?
Belongs to the protamine P1 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome.
Protein: RS14_ECOLI
Sequence: MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNAVLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14, Small ribosomal subunit protein uS14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: RSMJ_SHIDS
Sequence: MQICLIDETGTGDGALSVLATRWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTDITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLASKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RNH_ANAD2
Sequence: MSQARFIAFSDGSALVNPGGPGGTGFVVLDRARPAYRFGGTRWVEDGPNAVTNNRMELRAVLEALEGLPGGEQVEVISDSRYVVDALSRWIHGWRKKGWRTASGEPVLNRDLIEALDARASALTVRYTWVRGHDGHAVNEVVDQLAQAAARGVAGPGEAEVVAALRAEAFLAGGSAAPRSSRA
What is the function of this protein?
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
What are the official names of this protein?
Ribonuclease H, RNase H.
What is the protein family that this protein belongs to?
Belongs to the RNase H family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BETA_PSEPF
Sequence: MSQEFDYIIVGAGSAGNTLATRLTEDEGVTVLLLEAGGPDYRFDFRTQMPAALAFPLQGRRYNWAYETDPEPHMDGRRMECGRGKGLGGSSLINGMCYIRGNAMDYDGWAKLPGLEDWSYLDCLPYFRKAETRDIGPNDYHGGDGPVSVTTPKAGNNPLFHAMVEAGVQAGYPRTEDLNGYQQEGFGPMDRTVTPNGRRASTARGYLDVAKKRSTLTIVTHALTDKVLFEGKRAVGVRYLVGAAEERVEARARKEVIVCSGAIASPQLLQRSGVGPAKLLESLDIPVVHDLPGVGENLQDHLELYLQYACTQPVSLYPSLLWYNQPAIGAEWLFNGTGIGASNQFEAGGFIRTRPEFEWPNIQYHFLPVAINYNGSNGVKEHGFQAHMGSMRSPSRGRVQVKSKDPRQHPSILFNYMATEQDWQEFRDGIRLTREIMQQPALDAFRGREISPGIEVQTDEQLDKFIREHAETAFHPSCSCKMGTDDMAVVDGEGRVHGMQGLRVVDASIMPIITTGNLNAPTIMMAEKIADKIRGRQPLPRSKAPYYVAGDAPVKGKAMRDVSAVAQ
What is the function of this protein?
Involved in the biosynthesis of the osmoprotectant glycine betaine.  Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
What are the official names of this protein?
Oxygen-dependent choline dehydrogenase, CDH, CHD, Betaine aldehyde dehydrogenase, BADH.
What is the protein family that this protein belongs to?
Belongs to the GMC oxidoreductase family.
Protein: SYP_FRATH
Sequence: MKATQTLIATTKELPKEAVLISHQYMLKAGLIKKLASGIYTWMPLGLKVLQKIQNIVRDEMNKAGASELLLPSILPSELLQETHRWDKFGPELLKLHDRHNRDFCYGPTHEEPIVDMARDTIKSYKQLPLNLYQIQTKFRDEIRPRFGVMRAREFIMKDAYSFHENSQCLRNTYNTMYATYCNILDKIGLAYRPVKADTGAIGGDNSHEFQVLANAGEDIICYSNGSDYAANIELATYAKPDLSKRVNSQNTIEKIHTPNIKTIEKLCKEMSFDIKKTIKTMVIKDAGGNFFALVIRGDHELNETKINKLDQIIAPYTLATKEEIFSIFNANPGSLGIYNCPISIIADYSAIAITDLVCGANEDDYHFTNVNWDRDVTNYQIADIRNVVTGDISPDGKGTLELTNGIEVGHIFELEDVYSKPMNANIIGQDGKSKPMLMGCYGFGVSRVMAAAIEQSHDENGIIWPESIAPYQVAILPINYNKSDKVKEVADKLCQDLLGDGIDVLLDDRGARPGVMFADADLIGYSHHVVIGDRLLEQGLIEYKNRKTQEKQEITIAELIKLLK
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NEPR1_XENTR
Sequence: MNSLEQAEDLKAFERRLTEYVSCLQPATGRWRMILIVVSVCTATGAWNWLIDPETQKVSFFTSLWNHPFFTISCITLIGLFFAGIHKRVVAPSIIAARCRTVLAEYNMSCDDTGKLILKPRPHVQ
What is the function of this protein?
May form with the serine/threonine protein phosphatase ctdnep1 an active complex dephosphorylating and activating lipins.  Lipins are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels.  May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics.  May also indirectly regulate the production of lipid droplets and triacylglycerol (By similarity).
What are the official names of this protein?
Nuclear envelope phosphatase-regulatory subunit 1, Transmembrane protein 188.
What is the protein family that this protein belongs to?
Belongs to the CNEP1R1 family.
What are the subcellular locations of this protein?
Nucleus membrane; Multi-pass membrane protein. Cytoplasm.
Protein: NDPA_SHEDO
Sequence: MSINIEQAIIHEISQDSQGQLRCRLRPQPLLNSQAVEAMLEELHQTYSGKAGKGFGFFGTHGEDGEANPAFADGLSQYRSGDLGFVEFTGVASKLLQEELAKYDFSQGGFLLMSCYTSMTSDYLFVALLSAKSSMTVLDDMELSQNNHLDLNNIQLAARIDLTEWQADKDSRKYISFIRGRAGRKVADFFLDFMGCVEGVNIKAQNKTLMHAVEDFVSGSELTKDERQQCRDKVFDYCSERAEVGADIELKDLADELADSGMDSFYDFASSGTYELDEEFPADKASLRQLKKFSGTGGGVTLSFDGGHLGERVIYDPISDTLLIKGVPANLKDQLDRRLKG
What are the official names of this protein?
Nucleoid-associated protein Sden_2335.
What is the protein family that this protein belongs to?
Belongs to the YejK family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: HEMH_YERP3
Sequence: MMQSKPGVLMVNLGTPDAPTSKAIKRYLAEFLSDRRVVDTSPLLWWPLLHGVILPLRSPRVAKLYQSVWMEEGSPLLVYSRRQQKALAARMPDIPVELGMSYGSPNLPEAIEKLLAQGVTNLVILPLYPQYSCSTSAAVWDAVARVLKGYRRLPSISFIRDYAEHPAYISALKQSVERSFAEHGQPDRLVMSFHGIPKRYAQLGDDYPIRCEDTSRALRAALPLPAEKIIMTYQSRFGREPWLTPYTDETLKSLPSQGVKHIQLICPGFSADCLETLEEIKEQNREFFLHAGGEKFEYIPALNDDEGHIALLEQLIRHNI
What is the function of this protein?
Catalyzes the ferrous insertion into protoporphyrin IX.
What are the official names of this protein?
Ferrochelatase, Heme synthase, Protoheme ferro-lyase.
What is the protein family that this protein belongs to?
Belongs to the ferrochelatase family.
What are the subcellular locations of this protein?
Cytoplasm.