PharMolix/UniProtQA huggingface dataset:
Protein: PNP_ZYMMO
Sequence: MFDIKRQEIDWGGKKLTLETGQVARQADGAVIATLGETVVLCAVTAAKTVKEGQDFFPLTVHYQEKYSAAGRIPGGFFKRERGATERETLISRLIDRPIRPLFPEGFYNETLVIAQVMSYDGENEPDILAMIAASAALALSGVPFLGPIGAARVGYQDGEFILNPTLEQLEKSDLDLVVGATRDAVMMVESEANELPEEVMLNAVSFAHESLQPVIKAIINLAEQAAKEPWELVSYDDSALAAKVEELCYDNFDKAYRLTRKAERVDALSKAKAVLDEAFPEADPTEKLRIQKLAKKLEAKIVRTAILKEGRRIDGRDLKTVRPIRSQVGFLPRTHGSALFTRGETQALVSTTLGTADAEQMIDGLTGLHYERFMLHYNFPPYSVGEVGRFGAPGRREIGHGKLAWRALHPVLPSKADFPYTIRVLSDITESNGSSSMATVCGGCLALMDAGVPLTRPVSGIAMGLILEKDGFAILSDIMGDEDHLGDMDFKVAGTEKGITSLQMDIKVAGITEEIMQKALEQAKGGRAHILGEMSKALGEVRSEISNLAPRIETMSVPKDKIRDVIGTGGKVIREIVATTGAKVDIEDDGTVRLSSSDPANIEAAREWINGIVEEPEVGKIYNGKVVNIVDFGAFVNFMGGRDGLVHVSEIKNERVNKVSDVLSEGQEVKVKVLEIDNRGKVRLSMRVVDQETGAELDDNRPPRENAERRGGERPRRDRGPRRESGDRPARRDMEPEFAPAFLRKDS
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KAD_DEHMB
Sequence: MYNVIFLGAPGSGKGTQGEVVAKELKLAHMATGDLFRKAIECGDELGDTVKSYMERGELVPDEITISVVLKHLAGLKDVTGIILDGFPRSLRQAEALDEALVQQGQGIGRVIYINVPEDELVRRLSGRWVCRSCQSPYQSGCAEVTKGKCSRCQGELYQRPDDTPETVKERLKVYFSKTAPLIEYYRSKGKLSEIDGMAEISEVTKRIISAIKCGK
What is the function of this protein?
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP.  Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
What are the official names of this protein?
Adenylate kinase, AK, ATP-AMP transphosphorylase, ATP:AMP phosphotransferase, Adenylate monophosphate kinase.
What is the protein family that this protein belongs to?
Belongs to the adenylate kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATL61_ARATH
Sequence: MKESDAVILIHLGINIVFAFFFFGISAVVVSCIIKCYNTHDDDHDHDNNNDGHVSITIKERVGIKPYVLRSIPIVDFNTKDFKYVLECVVCLSELADGDKARVLPSCDHWFHVECIDSWLQSNSTCPICRKRVCLKQSRTRPELGGRDKSFNQNHDQTSEHHEFSTDPPTNTDTAIIEDGGCGEANEGQPELTAVVIDIPAKEI
What are the official names of this protein?
Putative RING-H2 finger protein ATL61, RING-type E3 ubiquitin transferase ATL61.
What is the protein family that this protein belongs to?
Belongs to the RING-type zinc finger family. ATL subfamily.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: IPK1_CANGA
Sequence: MLVAEGGANILLELDHRGVLYRCNVRDKSLKVNNEYTYKNYRYINQVVRPLLGDCIPEMELVDIPYDRISGIIGDFVGDPDSDHVSALTIKNLRPTNVYGEKIRYDDHFTKVYHDDTMEHILVEIKPKWLHHAKFCRNCTHNNLKNRKIPYCYALMVVDPSHVSDMLLHTGIAFPRKFLIKFVDYFSKSDNILAKLHDIQKNLDSNVSMNDIKSIDDVSDAFLLNMTLKDVSCFIEWTREPDSLEVNVVDVDMKLVSKLDHWVNTHIQLSNSSNLVHH
What is the function of this protein?
Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
What are the official names of this protein?
Inositol-pentakisphosphate 2-kinase, Inositol-1,3,4,5,6-pentakisphosphate 2-kinase, Ins(1,3,4,5,6)P5 2-kinase, InsP5 2-kinase.
What is the protein family that this protein belongs to?
Belongs to the IPK1 type 1 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RR18_CITSI
Sequence: MDKTKRLFLKSKRSFRRRLPPIQSGDRIDYRNMTLISRFLSEQGKILSRRVNRLTLKEQRLITIAIKQARILSSLPFLNNEKQFERSGLTARPPGLRTRKK
What are the official names of this protein?
30S ribosomal protein S18, chloroplastic.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS18 family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: CWC23_KLULA
Sequence: MDLAHVKDNHVDLYRILHIHVNDNEHLNSVTPTLINKQFRKLSLTLHPDKSNESDLNITRDRWDNLQSAYRILSEHKKEYDIWYQRTFLHSNRELLEKLEISEKAKKEKLISYDEIEKIQRYGQTLRKLVHFEIPISDWRNPSFTENTDDLNKLTETCLFRIKLVKRKEYNNEQKLNEWFRKIDIPITVQYYSENNDQREDDLVVYASARNVQTTIEILRTIENEKELHPDILEFTPAVEFEHFSFKEKVELDPSLGSIIYNSSDNPIIM
What is the function of this protein?
Involved in pre-mRNA splicing.  May be involved in endoplasmic reticulum-associated protein degradation (ERAD) and required for growth at low and high temperatures (By similarity).
What are the official names of this protein?
Pre-mRNA-splicing factor CWC23.
What is the protein family that this protein belongs to?
Belongs to the DnaJ family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: RS212_GLOVI
Sequence: MTEVRLGENESIESALKRFKKKIQKAGILSEIKRRERYEKPSARRKRKAEAARKRRR
What are the official names of this protein?
30S ribosomal protein S21 2.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS21 family.
Protein: RS13_PSESM
Sequence: MARIAGVNIPDNKHTVISLTYIYGVGRTTAQKICATTGVNPAVKIKDLSDEQIEQLRGEVAKFTTEGDLRREINMKIKRLMDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIRK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: CH60_THENE
Sequence: MPKLLKFNEEARRALERGVDKVANAVKITLGPKGRNVVIEKSWGSPTITNDGVSIAKEIELEDKFENLGAQLVKEVASKTNDVAGDGTTTATVLAQAMIKEGLKNVAAGANPILLKRGIDKAVERAVEEIKKLSKKLSGREDIAHVAAISANSPEIGELIAEAMDKVGEDGVITVEDSKTLETYVEFTEGMQFDRGYISPYFVTDAEKMEVVLKEPSILITDRKLSAVKPLIPILEKVAQTGKPLLVIAEDVEGEALTTLVLNKLKGTLQSCAVKAPGFGERRKAMLQDIAILTGGQVASEELGINLEDLTLEDLGRADLVRVKKDETIIIGGKGDPEAIKKRIAQIKAQIEETTSEYEKETLQERMAKLAGGVAVIKVGAATETELKEKKHRIEDALSATRAAVEEGIVPGGGVTLLRSRKAVEKLLEELDGDEKIGAQIVYKALSAPIRQIAENAGYDGAVIIEKILASDDPAYGFDALRGEFGNMFEKGIIDPAKVTRSALQNAASIAGMLLTTEVLVVEKPEEKKETPSLPEEY
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NDK_HAHCH
Sequence: MAVERTLSIIKPDAVAKNVIGEIYSRFEKAGLRIVAAKMLHLSQEQAEGFYAEHKERGFFPDLVAFMTSGPVVVQALEGENAIALNRQLMGATNPKEAEPGTIRADFASSIDANAVHGSDSAASAEREVAYFFSENEICPRS
What is the function of this protein?
Major role in the synthesis of nucleoside triphosphates other than ATP.  The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
What are the official names of this protein?
Nucleoside diphosphate kinase, NDK, NDP kinase, Nucleoside-2-P kinase.
What is the protein family that this protein belongs to?
Belongs to the NDK family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y662_CHLP8
Sequence: MDNEFEMLKAGKLLIASANLLESNFKRTVLLMCEHNDEGSIGFILNKPMEFKVCEAISGFDEIDEPLHMGGPVQVDTVHFLHTRGDVIDDAQEVLPGLFWGGDKEQLSYLINTGVIRPSEVRFFLGYAGWSAGQLKDEFEEGSWYTADASNEQVFTDEYERMWSRTVRSKGGDYCLVANSPELPGMN
What are the official names of this protein?
UPF0301 protein Cpar_0662.
What is the protein family that this protein belongs to?
Belongs to the UPF0301 (AlgH) family.
Protein: FETP_LEPCP
Sequence: MARTVQCVLLKKEADGLDFSPYPGELGKRIYEQVSKEAWQQWLKHQTMLVNENRLNLADARARQYLARQMERYFFGEGADQPTGYVPPTA
What is the function of this protein?
Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.
What are the official names of this protein?
Probable Fe(2+)-trafficking protein.
What is the protein family that this protein belongs to?
Belongs to the Fe(2+)-trafficking protein family.
Protein: ADCS_YEAST
Sequence: MLSDTIDTKQQQQQLHVLFIDSYDSFTYNVVRLIEQQTDISPGVNAVHVTTVHSDTFQSMDQLLPLLPLFDAIVVGPGPGNPNNGAQDMGIISELFENANGKLDEVPILGICLGFQAMCLAQGADVSELNTIKHGQVYEMHLNDAARACGLFSGYPDTFKSTRYHSLHVNAEGIDTLLPLCTTEDENGILLMSAQTKNKPWFGVQYHPESCCSELGGLLVSNFLKLSFINNVKTGRWEKKKLNGEFSDILSRLDRTIDRDPIYKVKEKYPKGEDTTYVKQFEVSEDPKLTFEICNIIREEKFVMSSSVISENTGEWSIIALPNSASQVFTHYGAMKKTTVHYWQDSEISYTLLKKCLDGQDSDLPGSLEVIHEDKSQFWITLGKFMENKIIDNHREIPFIGGLVGILGYEIGQYIACGRCNDDENSLVPDAKLVFINNSIVINHKQGKLYCISLDNTFPVALEQSLRDSFVRKKNIKQSLSWPKYLPEEIDFIITMPDKLDYAKAFKKCQDYMHKGDSYEMCLTTQTKVVPSAVIEPWRIFQTLVQRNPAPFSSFFEFKDIIPRQDETPPVLCFLSTSPERFLKWDADTCELRPIKGTVKKGPQMNLAKATRILKTPKEFGENLMILDLIRNDLYELVPDVRVEEFMSVQEYATVYQLVSVVKAHGLTSASKKTRYSGIDVLKHSLPPGSMTGAPKKITVQLLQDKIESKLNKHVNGGARGVYSGVTGYWSVNSNGDWSVNIRCMYSYNGGTSWQLGAGGAITVLSTLDGELEEMYNKLESNLQIFM
What is the function of this protein?
Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine.  Required for the synthesis of 4-aminobenzoate (PABA), an important component in tetrahydrofolate biosynthesis.
What are the official names of this protein?
Aminodeoxychorismate synthase, ADC synthase, P-aminobenzoic acid synthase, PABA synthase, Para-aminobenzoate synthase.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the anthranilate synthase component I family.
Protein: ZN326_MOUSE
Sequence: MDFEDDYVHSTCRGAYQDFNGMDRDYGPGSYGGLDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQTRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRSYDAFGGPSTGRGRGRGHMGDFGSFHRPGIIVDYQNKPANVTIATARGIKRKMMQIFIKPGGAFIKKPKLAKPMDKMNLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVMEFLHECMVNKFKKASIRKQQTLNHPEAYKIIEKDIMEGVTADDHMMKVETVHCSACSVYIPALHSSVQLHLKSPDHSKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHPQDQQIEGDEEDEEKIDEPIEEEEEEEEEEEEEGEEAGSVEEEGDVEGEEGTAEAAAAGEADAVGEAEGAGEAEEAEEEEEEEGTQEFAAQACATEQCEHRQM
What is the function of this protein?
Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions (By similarity).  May also play a role in neuronal differentiation.  Able to bind DNA and activate expression in vitro.
What are the official names of this protein?
DBIRD complex subunit ZNF326, Zinc finger protein 326, Zinc finger protein interacting with mRNPs, Zinc finger protein-associated with nuclear matrix of 75 kDa.
What is the protein family that this protein belongs to?
Belongs to the AKAP95 family.
Protein: UL58_HCMVA
Sequence: RFTSRNTAPRWYKRDESGLATSIAAITTDFRCAPPTKRRTSYTPQKPARLRAPNLCVISTSQHDTNRVTWFPEHVRGTDPRHVLEDLTVYESIKQEKIRTLKLCVFIFPSPSFYQKTHFSSCKK
What are the official names of this protein?
Uncharacterized protein UL58.
Protein: HSLU_ACIF2
Sequence: MSEMTPREIVQELDKYIIGQSEAKRAVAIALRNRWRRGQVPPPLHQEITPKNILMIGPTGVGKTEIARRLAQLANAPFIKVEATKFTEVGYVGKDVESIIRDLTETAVDMIRNERQVALRQRAEELAEERILDILIPGPRDSSVPRSDEGTRQKFRKMLREGKLDAQEIEIEVSAPKGGVEIMAPAGMEEMTNQLREMFSNMAPGKTSTRRVTVSEAQRLLTDDEAAKLVNEEEVRALALERVQSGGIVFIDEIDKVAVRSGTQQGSDVSREGVQRDLLPLVEGSNVSTRYGVVKTDHILFIASGAFHLSKPSDLIPELQGRLPIRVELEALSAADLVRILQEPENALVRQYGALLASDGLALHFTQDGVQRIAEIAQQVNERVENIGARRLHTVMERLLEEVAFVAPDGSTTALEVDAAYVDSRLKDLAQDEDLSRYIL
What is the function of this protein?
ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.  The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV.  HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
What are the official names of this protein?
ATP-dependent protease ATPase subunit HslU, Unfoldase HslU.
What is the protein family that this protein belongs to?
Belongs to the ClpX chaperone family. HslU subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXP3_MACFA
Sequence: MPNPRPGKPSAPSLALGPSPGASPSWRAAPKASDLLGARGPGGIFQGRDLRGGAHASSSSLNPMPPSQLQLPTLPLVMVAPSGARLGPLPHLQALLQDRPHFMHQLSTVDAHARTPVLQVHPLESPAMISLPPPTTATGVFSLKARPGLPPGINVASLEWVSREPALLCTFPNPGAPRKDSTLSAMPQSSYPLLANGVCKWPGCEKVFEEPEDFLKHCQADHLLDEKGRAQCLLQREMVQSLEQQLVLEKEKLSAMQAHLAGKMALTKASSVASSDKGSCCIVAAGSQGSAVPAWSGPREAPDSLFAVRRHLWGSHGNSTFPEFLHNMDYFKFHNMRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCFVRVESEKGAVWTVDELEFRKKRSQRPSRCSNPTPGP
What is the function of this protein?
Transcriptional regulator which is crucial for the development and inhibitory function of regulatory T-cells (Treg).  Plays an essential role in maintaining homeostasis of the immune system by allowing the acquisition of full suppressive function and stability of the Treg lineage, and by directly modulating the expansion and function of conventional T-cells.  Can act either as a transcriptional repressor or a transcriptional activator depending on its interactions with other transcription factors, histone acetylases and deacetylases.  The suppressive activity of Treg involves the coordinate activation of many genes, including CTLA4 and TNFRSF18 by FOXP3 along with repression of genes encoding cytokines such as interleukin-2 (IL2) and interferon-gamma (IFNG).  Inhibits cytokine production and T-cell effector function by repressing the activity of two key transcription factors, RELA and NFATC2.  Mediates transcriptional repression of IL2 via its association with histone acetylase KAT5 and histone deacetylase HDAC7.  Can activate the expression of TNFRSF18, IL2RA and CTLA4 and repress the expression of IL2 and IFNG via its association with transcription factor RUNX1.  Inhibits the differentiation of IL17 producing helper T-cells (Th17) by antagonizing RORC function, leading to down-regulation of IL17 expression, favoring Treg development.  Inhibits the transcriptional activator activity of RORA (By similarity).  Can repress the expression of IL2 and IFNG via its association with transcription factor IKZF4 (By similarity).
What are the official names of this protein?
Forkhead box protein P3.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Note=Predominantly expressed in the cytoplasm in activated conventional T-cells whereas predominantly expressed in the nucleus in regulatory T-cells (Treg). The 41 kDa form derived by proteolytic processing is found exclusively in the chromatin fraction of activated Treg cells.
Protein: NADK_SALEP
Sequence: MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCAQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYNINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
What is the function of this protein?
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP.  Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
What are the official names of this protein?
NAD kinase, ATP-dependent NAD kinase.
What is the protein family that this protein belongs to?
Belongs to the NAD kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MDCC_PSESM
Sequence: METLSFEFPAGQPPKGRALVGVVGSGDLEVLLEPGQPGKLSIQVVTSVNGASLRWKHLFERMFDGQTPPALSIDIHDFGATPGVVRLRLEQGFEEIGHD
What is the function of this protein?
Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism.
What are the official names of this protein?
Malonate decarboxylase acyl carrier protein, Malonate decarboxylase subunit delta.
What is the protein family that this protein belongs to?
Belongs to the MdcC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL24_SULSY
Sequence: MIKLKKGDPVIVLTGKDKGKVSKIKQIIRKDGKVKVVVEGVNVVKKHLRPIQGVREGGIVEIEKPIDISNVAYYDEKSKRPVKVGIKYVVEGNKISKVRINKKSGEIIDKVWEKIKKEV
What is the function of this protein?
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
What are the official names of this protein?
50S ribosomal protein L24.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL24 family.
Protein: Y1684_METTH
Sequence: MSLWPNRSRNWRVHCDCRGFNLDRHVSEINERILEGDAAVFTADEIKDMVRDGDVPSADEVDVVTTATCGVMSGTAAVMHLRVSEPGSFRKAASVELNGIPAYPGPCPNENLGSVDLFIYGTGHSREDPDYGGGFLFRDLLLGSEVEVRVTSVEGRVVESTVTMDDIETARIVGTRMAFRNYTALVNPGETPVKSIFNAFEMPENCGGLSFSGCGDINPLENDPSMETVHQGTGVLLNGARAIVLGEGTRSSPIKPNLMLSGDLHDMKPRYIGGFRTAAGPEIFNTVAVPVPVTSERVLENLMVLNSDIKLPVADVRDRSRVITEITYEDVWSGDVRPVHHPERCTDCAVCLAARRCPTHAIDNGLDLDRCFGCGVCAWSCPSGAYEMDTGTVRIGELAVPIICRQSDRLRARELSLELKKLIENGDFLMG
What are the official names of this protein?
Uncharacterized protein MTH_1684.
Protein: CARME_HUMAN
Sequence: MQRRRRPPPPTSRLPEGCGGGGGGSEEVEVQFSAGRWGSAAAVSAAAAAATRSTEEEEERLEREHFWKIINAFRYYGTSMHERVNRTERQFRSLPANQQKLLPQFLLHLDKIRKCIDHNQEILLTIVNDCIHMFENKEYGEDGNGKIMPASTFDMDKLKSTLKQFVRDWSETGKAERDACYQPIIKEILKNFPKERWDPSKVNILVPGAGLGRLAWEIAMLGYACQGNEWSFFMLFSSNFVLNRCSEINKYKLYPWIHQFSNNRRSADQIRPIFFPDVDPHSLPPGSNFSMTAGDFQEIYSECNTWDCIATCFFIDTAHNVIDYIDTIWKILKPGGIWINLGPLLYHFENLANELSIELSYEDIKNVVLQYGFKVEVEKESVLSTYTVNDLSMMKYYYECVLFVVRKPQ
What is the function of this protein?
N-methyltransferase that catalyzes the formation of anserine (beta-alanyl-N(Pi)-methyl-L-histidine) from carnosine.  Anserine, a methylated derivative of carnosine (beta-alanyl-L-histidine), is an abundant constituent of vertebrate skeletal muscles.  Also methylates other L-histidine-containing di- and tripeptides such as Gly-Gly-His, Gly-His and homocarnosine (GABA-His).
What are the official names of this protein?
Carnosine N-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the carnosine N-methyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Nucleus.
Protein: GCS2_AZOSB
Sequence: MSLEAFSPSRALSIGVELELQLVGTHDYDLVGAADDMLRLTAGLDLPGDIKPEMTDSMIEISTGVCDNHAMVLTQLDGLRAALVDIARRLNVGICGGGTHGFQDWGERRIFDNPRFHYLHELYGYLAKQFTVFGQHVHIGCPGPDAALYLVHGLSRYIPHLIALSASSPFLQGQDTGFQSSRLNAVFAFPLSGRAPFALSWSDFGAYFDKMSATGVVSSMKDFYWDIRPKPEYGTVEVRVMDTPLTVERAAALAAYIQALARYLMVERPIQPREDDYLVYTFNRFQACRFGYAGTYVDPENHTHCSIAEALEASFTRIEQHAIELGAEAAIGRLRADVASGRNDAWWLRGQLGPQVTLPEVVMAQCRRWMNGEGM
What is the function of this protein?
ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
What are the official names of this protein?
Putative glutamate--cysteine ligase 2, Gamma-glutamylcysteine synthetase 2, GCS 2, Gamma-GCS 2.
What is the protein family that this protein belongs to?
Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
Protein: GUAA_STACT
Sequence: MEMAKEQEMILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSYTIDPEIYNLGVPVLGICYGMQLTTKLLGGKVERANEREYGKAIIHAKADELFFGLPEEQTVWMSHSDKVIEIPEGFESIADSPSTPYAAIEDKERRIYGVQFHPEVRHTEYGNDILRNFVRRICDCTGEWTMENFIDLEIEKIREQVGDRKVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMDKLKGVSDPEQKRKIIGNEFVYVFDDEASKLEGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMQFELIEPINTLFKDEVRALGIELGIPEHLVWRQPFPGPGLGIRVLGEITEEKLEIVRESDAILREVIREEGLEREIWQYFTVLPGMRSVGVMGDYRTYDYTIGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDVTSKPPSTIEWE
What is the function of this protein?
Catalyzes the synthesis of GMP from XMP.
What are the official names of this protein?
GMP synthase [glutamine-hydrolyzing], GMP synthetase, Glutamine amidotransferase.
Protein: ACTB_CHICK
Sequence: MDDDIAALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF
What is the function of this protein?
Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells.  Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction.  In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
What are the official names of this protein?
Actin, cytoplasmic 1, Beta-actin.
What is the protein family that this protein belongs to?
Belongs to the actin family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton. Nucleus.
Protein: SYP_SALA4
Sequence: MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGLRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLVRNELSSYKQLPLNFFQIQTKFRDEVRPRFGVMRSREFLMKDAYSFHTSQESLQETYDAMYAAYSRIFSRMGLDFRAVQADTGSIGGNASHEFQVLAQSGEDDIVFSDVSDYAANIELAEAIAPQTPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEKTVKTLLVKAVKDSKSPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVINAGPGSLGPVNMPIPVIIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPVVADIRNVVAGDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNFDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVLMDDRKERPGVMFADMELIGIPHTIVIGDRNLDNDDIEYKYRRSGEKSLIKTGDIVDYLVKAIKG
What is the function of this protein?
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).  As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine.  One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP.  The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro).  The misacylated Cys-tRNA(Pro) is not edited by ProRS.
What are the official names of this protein?
Proline--tRNA ligase, Prolyl-tRNA synthetase, ProRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSAD_SYNY3
Sequence: MTELSGQPPKFGGSTGGLLSKANREEKYAITWTSASEQVFEMPTGGAAIMNEGENLLYLARKEQCLALGTQLRTKFKPKIQDYKIYRVYPSGEVQYLHPADGVFPEKVNEGREAQGTKTRRIGQNPEPVTIKFSGKAPYEV
What is the function of this protein?
PsaD can form complexes with ferredoxin and ferredoxin-oxidoreductase in photosystem I (PS I) reaction center.
What are the official names of this protein?
Photosystem I reaction center subunit II, Photosystem I 16 kDa polypeptide, PSI-D.
What is the protein family that this protein belongs to?
Belongs to the PsaD family.