PharMolix/UniProtQA huggingface dataset:
Protein: RS6_RUTMC
Sequence: MRHYEITLIVHPDQSAQVGTMMEKYKEIITTGGGKIHRKEDWGRKHLAYPIKKIYKAHYLMMNIECDQEVLDKLNYNFRFNDAILRNLIISEDGVITTPSIMMANKDKEKGRS
What is the function of this protein?
Binds together with S18 to 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S6.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS6 family.
Protein: MDTJ_ECO45
Sequence: MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLIKSGTRKARKPELEVNHGAV
What is the function of this protein?
Catalyzes the excretion of spermidine.
What are the official names of this protein?
Spermidine export protein MdtJ.
What is the protein family that this protein belongs to?
Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family. MdtJ subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: END4_HALS3
Sequence: MRVGAHVSIAGGVDNAVTNELDVGGNCGQIFTHSPQVWQDPNIGADEAAAFREGTAADLDGPWVIHSSYLVNLCTPKDDLRAKSIDSMQAEVDAAHTLGIPYVNVHLGAHTGAGVDDGLDNAASALDELDIPDDVTVLIESDAGSGTKLGGDFEHLHEVLTRSDQDLDVCIDTAHAFAAGYDLSTEAAVNDTLAAFDDVVGLDHLQYVHLNDSKHACGTNKDEHAHIGEGHIGEAGMRAFINHDAIADVPLVLETPHEDGRGFAWNIDRVRDLRA
What is the function of this protein?
Endonuclease IV plays a role in DNA repair.  It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate.
What are the official names of this protein?
Probable endonuclease 4, Endodeoxyribonuclease IV, Endonuclease IV.
What is the protein family that this protein belongs to?
Belongs to the AP endonuclease 2 family.
Protein: PME6_ARATH
Sequence: MDHKILLTPPKSLYTKCIITIIYVVSISHLNAHFITSCKQTPYPSVCDHHMSNSPLKTLDDQTDGFTFHDLVVSSTMDQAVQLHRLVSSLKQHHSLHKHATSALFDCLELYEDTIDQLNHSRRSYGQYSSPHDRQTSLSAAIANQDTCRNGFRDFKLTSSYSKYFPVQFHRNLTKSISNSLAVTKAAAEAEAVAEKYPSTGFTKFSKQRSSAGGGSHRRLLLFSDEKFPSWFPLSDRKLLEDSKTTAKADLVVAKDGSGHYTSIQQAVNAAAKLPRRNQRLVIYVKAGVYRENVVIKKSIKNVMVIGDGIDSTIVTGNRNVQDGTTTFRSATFAVSGNGFIAQGITFENTAGPEKHQAVALRSSSDFSVFYACSFKGYQDTLYLHSSRQFLRNCNIYGTVDFIFGDATAILQNCNIYARKPMSGQKNTITAQSRKEPDETTGFVIQSSTVATASETYLGRPWRSHSRTVFMKCNLGALVSPAGWLPWSGSFALSTLYYGEYGNTGAGASVSGRVKWPGYHVIKTVTEAEKFTVENFLDGNYWITATGVPVNDGL
What is the function of this protein?
Acts in the modification of cell walls via demethylesterification of cell wall pectin.
What are the official names of this protein?
Probable pectinesterase/pectinesterase inhibitor 6.
What is the protein family that this protein belongs to?
In the C-terminal section; belongs to the pectinesterase family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: PTGA_STAAU
Sequence: MFKKLFGKGKEVQKDIAIYAPLTGEFVKIEDIPDPVFAQKMMGEGFGINPTEGEVVSPIAGRVDNVFPTKHAIGLKADNGLELLVHIGLDTVQLDGEGFEVLVSSGDEVNVGDPLVRFNLEYINNNAKSVISPIIITNTDQAASINIYDENAVIKGETKVIDVTMN
What is the function of this protein?
The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane.  The enzyme II complex composed of PtsG and Crr is involved in glucose transport.
What are the official names of this protein?
PTS system glucose-specific EIIA component, EIIA-Glc, EIII-Glc, Glucose-specific phosphotransferase enzyme IIA component.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FOXL2_CAPHI
Sequence: MMASYPEPEDASGALLAPETGRAAKEPEAPAPPSPGKGGGGGAGAAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYSRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHSHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTNAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
What is the function of this protein?
Transcriptional regulator.  Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination (By similarity).  Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity).  Has apoptotic activity in ovarian cells (By similarity).  Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity).  Activates SIRT1 transcription under cellular stress conditions (By similarity).  Activates transcription of OSR2 (By similarity).  Is a transcriptional repressor of STAR (By similarity).  Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity).  Is a regulator of CYP19 expression.
What are the official names of this protein?
Forkhead box protein L2.
What are the subcellular locations of this protein?
Nucleus.
Protein: DCD_MARN8
Sequence: MSIKSDKWIRRMSEQHGMIEPFEAGQVRESEKGRVISYGTSSYGYDVRCSNEFKIFTNVHSATVDPKNFDENSFVNYTGDVCIIPPNSFALARTVEYFRIPRSVLTICLGKSTYARCGIIVNVTPLEPEWEGQVTLEFSNTTNLPAKIYANEGVAQMLFFESDEICETSYKDRGGKYLGQTGVTLPRT
What is the function of this protein?
Catalyzes the deamination of dCTP to dUTP.
What are the official names of this protein?
dCTP deaminase, Deoxycytidine triphosphate deaminase.
What is the protein family that this protein belongs to?
Belongs to the dCTP deaminase family.
Protein: RL13_STAAS
Sequence: MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: RS5_CHLAA
Sequence: MKRERINPETLELEERVVQINRVSKVVKGGRRFSFSTVVVVGDGKGHVGIGMGKAAEVPDAIRKGAEAAKRNLIRVPLVHATVPHEVVTKFAATKVMLRPAAPGTGVIAGRGVRPVVEAAGIKDLLSKVYGSNNPVNVVKATFKALSEMTSLHEMASRRDMTPQELMERRTRRETEAA
What is the function of this protein?
Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
What are the official names of this protein?
30S ribosomal protein S5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS5 family.
Protein: KDUI_ECOL6
Sequence: MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
What is the function of this protein?
Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate.
What are the official names of this protein?
4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase, 5-keto-4-deoxyuronate isomerase, DKI isomerase.
What is the protein family that this protein belongs to?
Belongs to the KduI family.
Protein: GALE_RAT
Sequence: MEEKVLVTGGAGYIGSHTVLELLEAGYSPVVIDNFHNSIRGEDSMPESLRRVQELTGRSVEFEEMDILDQAALQHLFKKHNFKAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMRAMGVKSLVFSSSATVYGKPVPASGRGPPHRGCTKPYGKSKFFIEEMIQDLCRADTAWNAVLLRYFIPIGAHRSARIGEDPQGIPNNLMPYVSQVAIGRREALNVFGDDYATEDGTGVRDYIHVVDLAKGHIAALKKLKEQCGCRIYNLGTGTGYSVLQMVQAMEKASGKKIPYKVVARREGDVAACYANPSLAHEELGWTAALGLDRMCEDLWRWQKQNPSGLGAHG
What is the function of this protein?
Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine.  The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate.  It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited.  Both UDP-sugar interconversions are important in the synthesis of glycoproteins and glycolipids.
What are the official names of this protein?
UDP-glucose 4-epimerase, Galactowaldenase, UDP-N-acetylglucosamine 4-epimerase, UDP-GlcNAc 4-epimerase, UDP-galactosamine 4-epimerase, UDP-GalNAc 4-epimerase, UDP-galactose 4-epimerase.
What is the protein family that this protein belongs to?
Belongs to the NAD(P)-dependent epimerase/dehydratase family.
Protein: GGA2_MOUSE
Sequence: MAATAVAAGTGSPAGTESAEGGPGAAAALELWLNKATDPSMAEQDWSAIQKFCEQVNTDPSGPTHAPWLLAHKIQSPQEKEALYALTVLEICMNHCGEKFHSEVAKFRFLNELIKVLSPKYLGAWATEKVKGRVIEILFSWTVWFPEDIKIRDAYQMLKKQGIIKQDPKLPMDKILPPPSPWPKSIFDADEEKSKLLTRLLKSNHPEDLQAANRLIKNLVKEEQEKSEKVSRRVSAVEEVRSHVRVLREMLSMYRRPGHALPDQQALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVRLYKQVVEGRVSAGNAVPAAVGAIPAPRAFPNPEPCGLNCPLIDLETPSLLHQDLAALGINDVPTRNQVVIPSCCNDKKQPGAITLMGGGIQSLSADRNLLDLFSPQPSPGLNYVPQKSIPKEVPPGTKASPGWSWEAGPLASSTASQNTPLAHVFVPLESVKPSSLPPIVVYDRNGFRILLHFSQTGAPGHPDVKVLLLTMMSTATQPVWDVMFQVAVPKSMRVKLQPASSSKLPAFSPLMPPAVISQTLLLDNPHKEPIRLRYKLTFNQGGQPFSEVGEVKDFPDLAVLSTA
What is the function of this protein?
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes.  Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (DXXLL) motif.  Mediates export of the GPCR receptor ADRA2B to the cell surface.  Regulates retrograde transport of phosphorylated form of BACE1 from endosomes to the trans-Golgi network.
What are the official names of this protein?
ADP-ribosylation factor-binding protein GGA2, Gamma-adaptin-related protein 2, Golgi-localized, gamma ear-containing, ARF-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the GGA protein family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Early endosome membrane; Peripheral membrane protein.
Protein: RS15_CITBB
Sequence: MLVTEKKQEIVNAHKLHDSDTGSPEVQIALLSERITYLTEHFKTHKKDHHSRRGLLKIVGQRRGLLDYLKKKDVERYKSIIAKLGIRR
What is the function of this protein?
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
What are the official names of this protein?
30S ribosomal protein S15.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS15 family.
Protein: WHY2_SOLTU
Sequence: MLKVSRLLHPRNQLLHKKLPGECVKGSIWQHAINTFAGFSTVRQNVVADAGKREGRVFAPYSVFKGKAALSAEPRLPTFNRLDSGGVKLNRRGVIMLTFWPSVGERKYDWEKRQLFALSATEVGSLISMGTRDSSEFFHDPSMLSSNAGQVRKSLSIKPNADGSGYFISLSVVNNNLKTNDRFTVPVTTAEFAVMRTAFSFALPHIMGWDRFTNRPSESISQSPSKVVPQLMEAEWDR
What is the function of this protein?
Single-stranded DNA-binding protein that may be involved in the maintenance of mitochondrial genome stability by preventing break-induced DNA rearrangements.
What are the official names of this protein?
Single-stranded DNA-binding protein WHY2, mitochondrial, Protein WHIRLY 2, StWHY2.
What is the protein family that this protein belongs to?
Belongs to the Whirly family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: PROB_NEIMF
Sequence: MKYKRIVFKVGTSSITHSDGSLSRGKIQTITRQLAALHHAGHELVLVSSGAVAAGFGALGFKKRPVKIADKQASAAVGQGLLMEEYTANLSSDGIVSAQILLSRADFADKRRYQNAGGALSVLLQRRAVPIINENDTVSVEELKIGDNDTLSAQVAAMIQADLLVLLTDIDGLYTGNPNSNPDAVRLDKIEHINHEIIEMAGGSGSANGTGGMLTKIKAATIAAESGVPVYICSSLKPDALAEAAEHQADGSFFVPRAKGLRTQKQWLAFYSESRGSVYVDEGAEHALSEQGKSLLMSGIAGIEGHFSRMDTVTVYSKATKQPLGKGRVLFGSAAAEDLLKSRKAKGVFIHRDDWISITPEIRLLLTEF
What is the function of this protein?
Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
What are the official names of this protein?
Glutamate 5-kinase, Gamma-glutamyl kinase, GK.
What is the protein family that this protein belongs to?
Belongs to the glutamate 5-kinase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PPR27_ARATH
Sequence: MFPKSLAVSRKNSNLTKGVSGLRRLCSSSSTITGSPCPPRYDVAVIADLIEKQHWSKLGVHVTDINPNELFRQLISSELDPDLCLRYYSWLVKNSDISVSLELTFKLLHSLANAKRYSKIRSFLDGFVRNGSDHQVHSIFHAISMCDNVCVNSIIADMLVLAYANNSRFELGFEAFKRSGYYGYKLSALSCKPLMIALLKENRSADVEYVYKEMIRRKIQPNVFTFNVVINALCKTGKMNKARDVMEDMKVYGCSPNVVSYNTLIDGYCKLGGNGKMYKADAVLKEMVENDVSPNLTTFNILIDGFWKDDNLPGSMKVFKEMLDQDVKPNVISYNSLINGLCNGGKISEAISMRDKMVSAGVQPNLITYNALINGFCKNDMLKEALDMFGSVKGQGAVPTTRMYNMLIDAYCKLGKIDDGFALKEEMEREGIVPDVGTYNCLIAGLCRNGNIEAAKKLFDQLTSKGLPDLVTFHILMEGYCRKGESRKAAMLLKEMSKMGLKPRHLTYNIVMKGYCKEGNLKAATNMRTQMEKERRLRMNVASYNVLLQGYSQKGKLEDANMLLNEMLEKGLVPNRITYEIVKEEMVDQGFVPDIEGHLFNVSTKS
What are the official names of this protein?
Pentatricopeptide repeat-containing protein At1g09820.
What is the protein family that this protein belongs to?
Belongs to the PPR family. P subfamily.
Protein: NIFS_FRASE
Sequence: MIYLDHNATTPVDPRVVEVMLPLFTERFANPASKHAPGQEATRIVERARREVASLAGARPREIVFTSGATEAANLAIGGVLATAEPGRRRILVGATEHPAVLGAADAAVSAGSAVSADGTTAAERIAVHPDGTVDVDDLRRRLGPDVALVAVMAANNETGAVNDPRPLVEAARSAGRCCCADVTQALGRVPVEFERTGVDLAVSSAHKLYGPKGVGALIASKDAWSRLAPRVHGGGQERGLRAGTLNTAGIAGFGAAARIAAESMADDGTRQRALVALLTELLVKRLGPGAVELNGPVRARLPNTVNLRFVGAGADEVQACAPRVAISAGSACSGGGDEPSHVLRAMGRTATEARESLRFSLGRATTTEEIRTAADLVARAVLRVRSLSQSTPIQDEVRDDNRASSNSLNRGSAASKES
What is the function of this protein?
Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.  Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.
What are the official names of this protein?
Cysteine desulfurase, Nitrogenase metalloclusters biosynthesis protein NifS.
What is the protein family that this protein belongs to?
Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
Protein: P4KG4_ARATH
Sequence: MSSAGVALSPVRSEPLIMPLVRANSCLDSYPDDTIMIYLTLPGSVIPMRVLESDSIESVKLRIQSYRGFVVRNQKLVFGGRELARSNSNMRDYGVSEGNILHLVLKLSDLQVLDVKTTCGKHCRFHVERGRNIGYVKKQISKKRGDFVDPDEQEILYEGEKLEDQSLINDICRNDDSVLHLLVRRSAKVRVKPVEKNFELSIVAPQAKDKKGREAKSIVPPKKLSLEPVVVNSKAKVPLVVKDMIQSASDGLKSGNSPVRSSEGTGGAYFMQGPSGNKFVGVFKPIDEEPMAENNPQGLPLSPNGEGLKKGTKVGEGALREVAAYILDHPKSGNKSMFGEEIGFAGVPPTAMIECLHPGFNHPKGIKTKIGSLQMFTENDGSCEDMGPLSFPVEEVHKISVLDIRLANADRHGGNILMTKDESGKLVLVPIDHGYCLPESFEDCTFEWLYWPQARKPYSAETQEYIRSLDAEEDIDLLKFHGWKMPAETAQTLRISTMLLKKGVERGLTAFEIGTIMCRETLSKKSLVEEMVEEAQEAVLPGTSEAAFLEALSDVMDYHLDHSQEH
What is the function of this protein?
The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3) (By similarity).  Undergoes autophosphorylation and phosphorylates serine/threonine residues of protein substrates (PubMed:17880284).  Phosphorylates RPN10 and UFD1 in vitro (PubMed:17880284).
What are the official names of this protein?
Phosphatidylinositol 4-kinase gamma 4, AtPI4Kgamma4, PI-4Kgamma4, PI4K gamma 4, Ubiquitin-like domain kinase gamma 4, UbDK gamma 4.
What is the protein family that this protein belongs to?
Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISPE_GEODF
Sequence: MKTIECKAPAKVNYRLDVLRRRPDGYHDLRMIMQRIDLCDDIRISLSETPGVRVACGKEGVPDGPGNIAWRAADALLKLSGRCTGIDISIVKNIPVAAGLGGGSSDCASALMGVNELLELHLTDEQLMEAGSKLGADVPFFIFKKTALAEGIGDKLAAVEAAPAWLVIVNPNLAVSTAWVYQNLQLTAGKDEYIIPRFYGSVSDICAILANDLEKVTIGRFPVINQIKQKLLQVGAAGSLMSGSGSTVFGIFAEEAPARKAAEKLSRESDWFVAAVKTL
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: SDF2L_HUMAN
Sequence: MWSAGRGGAAWPVLLGLLLALLVPGGGAAKTGAELVTCGSVLKLLNTHHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRIRGGSEGGCPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMPSANTHNTWKAMEGIFIKPSVEPSAGHDEL
What are the official names of this protein?
Stromal cell-derived factor 2-like protein 1, SDF2-like protein 1, PWP1-interacting protein 8.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: HFLX_MAGMM
Sequence: MLETHQAPDRAILLQALEPKVTRDACQRLLDELVHLSTTAGLEVHATQLLSLQKAVPATYFGSGQVEELARRIEEDEIDVAVVNHALTPIQQRNLEKKLNAKVVDRTGLILEIFAARARTREGIMQVELASLMYQQSRLVRSWTHLERQRGGVGLRGGPGERQIEVDRRLIRERIHKLKKQLEEVERTRALQRQPRQDIPLFTVALVGYTNAGKSTLFNLLTRAGVLAEDKLFATLDPTMRAVDLPDGGRILLSDTVGFIRQLPHQLVAAFKATLEEVMSADMLLHVVDLSDPEWERYVESVNGVLQELEVQHTRTLTVYNKIDRLESRGILERELARGDTIGVSAQTGEGVEPLLSELRRAVGRAMLRYEVILPVSDGRWLAKFHAEASVVEVREGEDFTTLIVELAPAVLGRLQGEVEREGVEVQFRPVD
What is the function of this protein?
GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
What are the official names of this protein?
GTPase HflX, GTP-binding protein HflX.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
What are the subcellular locations of this protein?
Cytoplasm. Note=May associate with membranes.
Protein: RLA3_LEIIN
Sequence: MSTKYLAAYALASLSKASPSQADVEAICKAVHIDVDQATLAFVMESVTGRDVATLIAEGAAKMSAMPAASSGAAAGVTASAAGDAAPAAAAAKKDEPEEEADDDMGFGLFD
What is the function of this protein?
Plays an important role in the elongation step of protein synthesis.
What are the official names of this protein?
60S acidic ribosomal protein P2-2.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic ribosomal protein P1/P2 family.
Protein: BIOF_ECOL6
Sequence: MIWQEKIDAALDARRVADALRRRYPVAQGAGRWLVADDCQYLNFSSNDYLGLSHHPQIIRAWQQGADQFGVGSGGSGHVSGYSVAHQVLEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSPLRRFAHNDVTHLARLLASPCPGQQLVVTEGVFSMDGDSAPLEEIQQVTQQHDGWLMVDDAHGTGVIGEQGRGSCWLQKVKPELLVVTFGKGFGVSGAAVLCSNTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSWSAIQPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: CAPP1_SOYBN
Sequence: MANRNLEKMASIDAQLRLLVPAKVSEDDKLVEYDALLLDRFLDILQDLHGEDLKETVQEVYELSAEYEGKHDPKKLEELGNLITSLDAGDSIVVAKSFSHMLNLANLAEEVQIAHSRRNKLKKGDFADENNATTESDIEETLKKLVVDMKKSPQEVFDALKNQTVDLVLTAHPTQSVRRSLLQKHGRIRNNLTQLYAKDITPDDKQELDEALQREIQAAFRTDEIRRTPPTPQDEMRAGMSYFHETIWKGVPTFLRRVDTALKNIGINERVPYNAPLIQFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANLYYSQIEDLMFELSMWRCNDELRVRADELNRSSKKNSVAKHYIEFWKAIPPNEPYRVLLGEVRNRLYQTRERSRHLLAHGYSDIPEEETFTNVEEFLEPLELCYRSLCACGDRAIADGSLLDFLRQVSTFGLSLVRLDIRQESDRHTDVLDAITKHLEIGSYQEWSEEKRQQWLLSELSGKRPLFGPDLPQTEEIRDVLETFHVIAELPLDNFGAYIISMATAPSDVLAVELLQRECHVKHPLRVVPLFEKLADLEAAPAALARLFSVDWYRNRINGKQEVMIGYSDSGKDAGRFSAAWQLYKAQEELIMVAKQYGVKLTMFHGRGGTVGRGGGPTHLAILSQPPETIHGSLRVTVQGEVIEQSFGEQHLCFRTLQRFTAATLEHGMHPPISPKPEWRALMDEMAVIATEEYRSIVFKEPRFVEYFRLATPELEYGRMNIGSRPAKRRPSGGIETLRAIPWIFAWTQTRFHLPVWLGFGAAFKHVIEKDVRNIHVLQEMYNQWPFFRVTIDLVEMVFAKGDPGIAALYDRLLVSEDLWSFGEQLRTMYEETKELLLQVAGHRDLLEGDPYLKQRLRLRDSYITTLNVCQAYTLKRIRDPNYNVKLRPHISKESIEISKPADELITLNPTSEYAPGLEDTLILTMKGIAAGLQNTG
What is the function of this protein?
Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
What are the official names of this protein?
Phosphoenolpyruvate carboxylase, housekeeping isozyme, PEPCase, PEPC 1.
What is the protein family that this protein belongs to?
Belongs to the PEPCase type 1 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTLD_SHIB3
Sequence: MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRIVPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPSMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLPHKNLIQGIAGAMHFRSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ
What are the official names of this protein?
Mannitol-1-phosphate 5-dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the mannitol dehydrogenase family.
Protein: RL17_SALDC
Sequence: MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKTEAAAE
What are the official names of this protein?
50S ribosomal protein L17.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL17 family.
Protein: RL21_AROAE
Sequence: MYAVIKTGGKQYRVAAGEKIKVEQIPADVGSEITIDQVFMVGEGESVKIGTPVVSGATVTATVVSHGRHDKIKIFKMRRRKHYQKHQGHRQNYTELRIEAISA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.
Protein: UBA4_YARLI
Sequence: MDRSDSEKTDVLPMFKQEYGRYGRQMLVPEFGISGQLDLRSKRILVVGAGGLGSPAIQYLAGAGIGHITIIDDDTVEESNLHRQTIHAGNVNVPKSESAAEFVGKLNPCISVTPMVVRLSPSNSFSVFEGHDLVLDCTDGPAVRYLINDTAVLSGIPVVSASALKTEGQLSIYNYNGGPCYRCLFPIPPPADAVQTCGDGGIMGPVVGMMGMSQAMEAIKLLTGVYSESFTPFLMLYSAYNFPPWKSVKVRKRQKTCAACGDVPRISRQLIETGQVDYSEFCGSPSQVLLGEEHRITPEEYSKIVSTKHILLDVRERPQFDITSFPRSINIPWSELKHKEELDVQVDGSPVYVVCRYGNDSQNAVDKLQKLGIPSKDIKGGLYAWAKNVDEKFPIY
What is the function of this protein?
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln).  Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1.  Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus.  The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1.  Subsequently, a transient disulfide bond is formed.  Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.  Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation.  May also be involved in protein urmylation.
What are the official names of this protein?
Adenylyltransferase and sulfurtransferase UBA4, Ubiquitin-like protein activator 4.
What is the protein family that this protein belongs to?
In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.