PharMolix/UniProtQA huggingface dataset:
Protein: HRH1_RAT
Sequence: MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHTVGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFILCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKCETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLRSDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCFRLDIMQKQSVAEGDVRGSKANDQALSQPKMDEQSLNTCRRISETSEDQTLVDQQSFSRTTDSDTSIEPGPGRVKSRSGSNSGLDYIKITWKRLRSHSRQYVSGLHLNRERKAAKQLGFIMAAFILCWIPYFIFFMVIAFCKSCCSEPMHMFTIWLGYINSTLNPLIYPLCNENFKKTFKKILHIRS
What is the function of this protein?
In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
What are the official names of this protein?
Histamine H1 receptor, H1R, HH1R.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RL13_ECOSM
Sequence: MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
What is the function of this protein?
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself.  It is important during the early stages of 50S assembly.
What are the official names of this protein?
50S ribosomal protein L13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL13 family.
Protein: TSR4_YEAST
Sequence: MSKIEELPPSDTDDHSYSSKPGDVFLAFVDAPVKETDDILVEDSFIGGEPKWLHPDSEPPAELLKCGACKSADNMKLLLQAFSPLDDEQMSAIQQRLGINNMSYINPQDDRVLYVFLCTECQRKGNSVRCIRGVKKNKNVDSLSEKMASTSLEKDFQINPFDLSNNSDSKCNAFSSNPFGGANANPFGADSINSNISQSKDEGKKKESATVSAKTARKLHDLQKDKEYDGNKCFKSCLLYVEEETFKNKKPAHLQLPKNLKIDKEALDLTGDEDLEKDPIKLDPRTEKLSKFLDDDTFQKFQEVVGYNPLQVLRYDLGGKPLLYAETKVDILSTVPRPGYNPSSQRIFEMQLMPKMIFDLEEVVSVDNGMEWGTILVFTDVENYMPEFDEHGVGYVEECVKVQWESRT
What is the function of this protein?
Required for processing of the 20S pre-rRNA at site D to generate mature 18S rRNA.
What are the official names of this protein?
20S rRNA accumulation protein 4.
What is the protein family that this protein belongs to?
Belongs to the TSR4 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MPPE1_AILME
Sequence: MALIRLGFGRQHFCLLKRRSFLMLKLAALVFAVVLFCEFLIYYLVIFRCDWPEVKTPASDSGQKTLKAMFLADTHLLGEVRGHWLDKLRREWQMERAFQTALRLLQPEVVFILGDIFDEGKWSSSQAWADDVERFQKIFRHPRHVQLKVVAGNHDIGFHYQMNAYKIKRFEKVFSPERLFSWKGINFVMVNSVALEGDGCHICSEAEAELIEISRKLNCSRKQERRSGPCPDPQLLPASAPVLLQHFPLYRRSDANCSGEDAAPLEERGIPFKERYDVLSQEASQQLLWWLRPRLILSGHTHSACEVLHGAEVPEISVPSFSWRNRNNPSFIMGSMTPTEYALAKCYLPYEDTVLATYCVAAGLLVVLILVHSELLPSPFLFGWNLLRKFKT
What is the function of this protein?
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi.  Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins (By similarity).
What are the official names of this protein?
Metallophosphoesterase 1, Post-GPI attachment to proteins factor 5.
What is the protein family that this protein belongs to?
Belongs to the metallophosphoesterase superfamily. MPPE1 family.
What are the subcellular locations of this protein?
Golgi apparatus, cis-Golgi network membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi- pass membrane protein. Note=Also localizes to endoplasmic reticulum exit site.
Protein: RL11_HALVD
Sequence: MAGTIEVLVPGGKANPGPPLGPELGPTPVDVQDVVNDINDQTAAFDGMEVPVTVEYDDDGSFSIEVGVPPTAALIKDEVGFDTGSGEPQENFVADMSIEQLKKVAEQKSSDLLSYDLKNASKEVAGTCASLGVTIEGEDARTFKQRIDGGDFDDYFDDE
What is the function of this protein?
Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
What are the official names of this protein?
50S ribosomal protein L11, L11E.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL11 family.
Protein: VF385_ASFWA
Sequence: MDEIINKYQAVEKLFKEIQQGLAAYDQYKTLISEMMHYNNHIKQEYFNFLMIISPYLIRAHSGETLRNKVNNEIKRLILVENINTKISKTLVSVNFLLQKKLSTDGVKTKNMWCTNNPMLQVKTAHNLFKQLCDTQSKTQWVQTLKYKECKYCHTDMVFNTTQFGLQCPNCGCIQELMGTIFDETHFYNHDGQKAKSGIFNPNRHYRFWIEHILGRNSEQELGTKQDPCGTKVLQQLKKIIKRDNKCIALLTVENIRKMLKEINRTDLNNCVSLILRKLTGVGPPQISESILLRGEYIFTEAIKIREKVCKKGRINRNYYPYYIYKIFDAILPPNDTTNRRILQYIHLQGNDTLANNDSEWESICMELPEIKWKPTDRTHCVHFF
What are the official names of this protein?
Zinc finger protein B385R, pB385R.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B385R family.
Protein: PURA_SALPA
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPSALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKVEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEYGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATP22_YEAS8
Sequence: MLKCICRVYSQPLAQMVTSPLFKHMGSAGTYTILPITNLRHLSTKNCPLKIKSNRSEPLQFGDFERQVPCSRKSGSSKNVQKRLYELRQLKTVLSETFGVTEYASFFESLRNALHINNCSENEKKKLLYDIILHQHELYPEVARKIGFYLPGEVHRWFWYHIPKSESFNHYLFLLKSDVLLFTSNYCTRFTNRLIKGTEMERQLATFQIFLHDETNIKFIMEKVLKLHTFDSLIALVNGLVKAKNFRFIKVFIQALLQKLEQHCYSGKDGAKQKNLRYVKFNNTLLYYLLKSGNVELFIKTFQEELKFIVSSGLLNHIDGNEHILNFPIHHYLNLLRISNRQEELFNVISCLQSSPLMKYKLFKEFLMGELIASFQAFRDPKLVCKYLLSSYSSKASANILNALGIWGWLYHSKSTTLTAPTLARELKNKNNILPNTMRIGSPVTVPILTELYRSLLSSSSVSLESGQFKNCLLDLYYKYKSFLSEEAHKYRYWRNDTGILNVFLNYIRFQAREPRLAYNVLLDFYSQPFAKKVVLTTTLCPFSIVAYKNHTLTQAELSELLQVMHKNGVPLTFKFCSAMVMHYVKMRDEKGARSWYNKILFGGFEIRHMALIQIIKDQGWPFPKNFDETLLTELVENNNIKEPTDSTLFTDEDMFEEDGKPRFNDDDVNKCTNIIRETLKSLN
What is the function of this protein?
Translation factor specific for subunit 6 of the mitochondrial ATPase.  Required for assembly of the CF(0) component of the ATPase (By similarity).
What are the official names of this protein?
Mitochondrial translation factor ATP22.
What is the protein family that this protein belongs to?
Belongs to the ATP22 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein: SWT14_ORYSJ
Sequence: MAGMSLQHPWAFAFGLLGNIISFMTYLAPLPTFYRIYKSKSTQGFQSVPYVVALFSAMLWIYYALLKSDECLLITINSAGCVIETIYIAVYLVYAPKKAKMFTAKLLLLVNVGVFGLILLLTLLLSAGDRRIVVLGWVCVGFSVSVFVAPLSIIRLVVRTKSVEFMPFSLSFSLTISAVVWFLYGLLIKDKYVALPNVLGFSFGVIQMGLYAMYRNSTPKAVLTKEVEAATATGDDDHSAAGVKEHVVNIAKLSAAVDVVKTREVHPVDVESPPAEAPPEEDDKAAAATAAAVAGAGEKKVAA
What is the function of this protein?
Confers blight susceptibility (PubMed:25988582).  Confers TAL effector-mediated susceptibility to Xanthomonas oryzae pv.  oryzae (PubMed:23879865).
What are the official names of this protein?
Bidirectional sugar transporter SWEET14, OsSWEET14.
What is the protein family that this protein belongs to?
Belongs to the SWEET sugar transporter family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: LEUD_CLOD6
Sequence: MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDKFISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPILECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKANRG
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 2 subfamily.
Protein: Y4XK_SINFN
Sequence: MTLRIIAHLLALTASLAGCTSTAPIYVEQPTPIFVRQESTVLKLESFHASEQQRLLAFLWKASRGRRDALHLVISGSSRLSAEAVHQARQMGIGASNIHLLDQNDRGHLRIEAVVYHALPPICRSLSSQLLNDEFFDQPIGCSTSHNLAVMINDPRDLLGNRFVKPSDGDRAAIPVTTYRTSTGKGGL
What are the official names of this protein?
Uncharacterized lipoprotein y4xK.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor.
Protein: RL19_XANCP
Sequence: MSKLNKTILADFEAAQIQRQLPEFNQGDTVVVNVKVKEGNRERVQAYEGVVIGTKNAGLNSAFTVRKISHGFGVERVFQTHSAIIDSVEVKRRGKVRAGKLYYLRGLEGKAARIKEDLAAAAQAKAARQAAAKAE
What is the function of this protein?
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
What are the official names of this protein?
50S ribosomal protein L19.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL19 family.
Protein: SACA3_HUMAN
Sequence: MVSALRGAPLIRVHSSPVSSPSVSGPRRLVSCLSSQSSALSQSGGGSTSAAGIEARSRALRRRWCPAGIMLLALVCLLSCLLPSSEAKLYGRCELARVLHDFGLDGYRGYSLADWVCLAYFTSGFNAAALDYEADGSTNNGIFQINSRRWCSNLTPNVPNVCRMYCSDLLNPNLKDTVICAMKITQEPQGLGYWEAWRHHCQGKDLTEWVDGCDF
What is the function of this protein?
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization.  It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane.  The processed form has no detectable bacteriolytic activity in vitro.
What are the official names of this protein?
Sperm acrosome membrane-associated protein 3, Cancer/testis antigen 54, CT54, Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, Lysozyme-like protein 3, Sperm lysozyme-like protein 1, Sperm protein reactive with antisperm antibodies, Sperm protein reactive with ASA.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 22 family.
What are the subcellular locations of this protein?
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein. Note=Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Protein: ACX14_CAEEL
Sequence: MHLNTSICEVDNPDLTEEREKGTFDTDKMAAVIYGSEKLARRRREISEAVSKIPELADTQPFPFMDRLEKITEGSRKLEVLNNNIRDIIDYDDNGERLHIYQEVTGMEGHPLALHEVMFIPALVSQASKEQQEKWLGRARRREIIGCYAQTEMGHGTNLRKLETTATYFPDTQEFVLNTPTTTALKWWPGALGKSSNYAVVVVDMIIKGKSYGPHPFMVQLRDEKTHIPLKGIVVGDIGPKMSFNGGDNGFLGFDKFRVPRTNLLMRHVRVEADGTYVKPPHAKVNHSAMVHVRSHMATGQGALLAQALIIAVRYSAVRRQGFLENKTQEVKVLDYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVTHQTGEGIEQARMACGGHGYSMASYISEIYGIAIGGCTYEGENMVMLLQLARYLVKSVELIKSGEAKKLGPMVSYLAAKGGHPDLSSLNGYVTAFEHMARRQAWKATEKFLKLMESGESREIAWNKSTVELTRASRLHTRLFIIEAFMRRVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALEFMSSTQLDYIRDQLYLYLEKIRPSAVSLVDSFQISDMQLRSVLGRRDGNVYENLFKWAKSSPLNKSDVLPSVDKYLMPMMEKAKL
What is the function of this protein?
Involved in the first step of peroxisomal beta-oxidation by catalyzing the desaturation of fatty acid-derived side chains of ascaroside pheromones, which regulates development and behavior (PubMed:29537254, PubMed:29863473).  Specifically, shortens ascarosides with a 9-carbon side chain (asc-C9) and, in association with acox-1. 1, may contribute to the shortening of ascarosides with a 11-carbon side chain (asc-C11) (PubMed:29537254, PubMed:29863473).  May contribute to the production of indol-3-carbonyl(IC)-ascarosides in association with acox-1. 1 and acox-3 (PubMed:29863473).
What are the official names of this protein?
Acyl-coenzyme A oxidase acox-1.4.
What is the protein family that this protein belongs to?
Belongs to the acyl-CoA oxidase family.
What are the subcellular locations of this protein?
Peroxisome.
Protein: Y1293_STREM
Sequence: MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKMLEDFHAARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTFNALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPEGMGRNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLNGITSGYAKFETFPVWNLPLHHPVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYASPTDMGVNMVGFSIVNEEAAIEASKQEIIRRYYQTLVDFKAERVTETAVKKLELLMNDIGVTPKDRQVTLIARQKAELTGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTLAHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKELGNLKGSEAHSTVILTNEDKHALRQLGINVTFDPVYQHHKLYRS
What are the official names of this protein?
UPF0371 protein Sez_1293.
What is the protein family that this protein belongs to?
Belongs to the UPF0371 family.
Protein: OXR1_NEUCR
Sequence: MSYHDARRRHPHPIQTFRPESEYSSSAPGSGAQTPTGSGASSSQLPGLVSSIWGGLIRRFSAETPSLTHSQSYPADSSHSHFDDHNYNNSNDNNGVDGVYVPPRFHETIQRTASPMQPPPLEPVQLKGFAPDTPASARILTQAIAEEIRIMVPTRLSIVDEWNLVYSLDQDGASLGTLYDKCAKYSGRRVGFVLVVKDAEGGIFGAYLSDFPHPAPKYFGTGECFLWRASVMASLPPPPSADTTNLRGRTSTISSVGTGTDTATNTATNHNSGDDLASCTVLRATTTATPPHNDSADDLFADLTGTVDQTTIRFKAFPYSGVNDYYILCESHFLSVGAGDGKFGLWLDDGLEKGVSSTSQTFGNEQLSDQGEKFSVLGVEVWVIGSGGL
What is the function of this protein?
May be involved in protection from oxidative damage.
What are the official names of this protein?
Oxidation resistance protein 1.
What is the protein family that this protein belongs to?
Belongs to the OXR1 family.
What are the subcellular locations of this protein?
Mitochondrion.
Protein: FTSB_ENT38
Sequence: MGKLTLLLLALLVWLQYSLWFGKNGLHDYGRVNDDVTAQQATNAKLKARNDQLFAEIDDLNGGQEAIEERARNELSMTKPDETFYRLVPDASKRNQGSAQNNR
What is the function of this protein?
Essential cell division protein.  May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
What are the official names of this protein?
Cell division protein FtsB.
What is the protein family that this protein belongs to?
Belongs to the FtsB family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass type II membrane protein. Note=Localizes to the division septum.
Protein: FER_DROME
Sequence: MGFSSALQSRAAHEALIVRQDAELRLMETMKRSIQMKAKCDKEYAISLTAVAQQGLKIDRADEMQGSLISKSWRSYMDELDHQAKQFKFNAEQLEVVCDKLTHLSQDKRKARKAYQEEHAKIAARLNHLTDEVVRKKSEYQKHLEGYKALRTRFEENYIKAPSRSGRKLDDVRDKYQKACRKLHLTHNEYVLSITEAIEVEKDFRNVLLPGLLEHQQSVQESFILLWRNILQEAAQYGDLTADKYKEIQKRIDTVIGSINPTEEYGEFTEKYKTSPTTPLLFQFDETLIQDIPGKLQSSTLTVDNLTVDWLRNRLQELEGAVRDCQEKQMKMIEHVNGGSPVANGSIISNGSNTSNGIQSNKDSLCRQSKDLNALRCQEKQKQKLVDMIKCALNEVGCEELPSGCDDDLTLEQNFIENGYNNEQQRSNSTSSPGLGIMNELMRRGGVLTLLRGRGRHFKRKSTPQPATPMTRSRQGRFNKLQPRSQSLGSLSVIRDGNGPSPARYEPITNHRLRQAASVHYLGEEIATSSTNPPDLTRLRRTQCSMLCLGEDEEPVVLASPAPLTQLTAAVLTNTNNNHIYADLELDKKKDTSPSPECKGEQIQPKKEQIRIEINQTAPQNSIDAHLDRIDELNRVLDDRLKRTLQPSDDVNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKDTSHSKKRSLSFSQKSISNIFSNLKEFSKSPLVRMGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNNNNKNTSSNSNHSASQSTIITSTITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKPCKQCTKRRRIHPSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQTTGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDNSH
What is the function of this protein?
Tyrosine-protein kinase which is required during embryogenesis for formation of the actin cable in leading edge cells of the dorsal epidermis and for the timely progression of dorsal closure.  May play a role in regulation of adherens junctions and cell adhesion through phosphorylation of the beta-catenin arm.
What are the official names of this protein?
Tyrosine-protein kinase Fer.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
What are the subcellular locations of this protein?
Membrane; Peripheral membrane protein. Cell junction, adherens junction. Note=At stages 11-12 of embryogenesis, localizes to adherens junctions in epidermal cells. At stages 13-14, is no longer detected in the epidermal cell junctions which border with the amnioserosa.
Protein: AAR2_BOVIN
Sequence: MAAMQMDPELARRLFFEGATVVILNMPKGTEFGIDYNSWEVGPKFRGVKMIPPGIHFLHYSSVDKANPREVGPRMGFFLNLQQRGLKVLRWDAAREEVDLSPAPEAEVEAMRANLQELDQFLGPYPYTTLKKWISLTNFISEATVEKLQPESRQICAFSEVLPVLSMRHTKDRVGQNLPRCGAECKSYQEGLARLPEMKPRAGTEIRFSELPTQMFPAGATPAEITRHSMDLSYALETVLSKQFPCSPQDVLGELQFAFVCFLLGNVYEAFEHWKRLLNLLCRSEEAMVKHHSLYVNLISILYHQLGEIPADFFVDIVSQDNFLTSTLQVFFSSARSVAVDATLRQKAERFQAHLTKKFRWDFEAEPEDCAPVVVELPDGVGTG
What is the function of this protein?
Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.
What are the official names of this protein?
Protein AAR2 homolog, AAR2 splicing factor homolog.
What is the protein family that this protein belongs to?
Belongs to the AAR2 family.
Protein: STR7_ARATH
Sequence: MLRFYHWRFPPSLAVVRMLSSPPPPHSHSPFSGGGVNSNSVGGNSKPELQFPQSQPHKLSSSPSSSLKSTVACSNAGAIRRSMATVSQAFSERTESIDSDLGSLVVVSFYKFADFPEHADFRKPLKDLCEKLRVSGGIILAPEGINGSICGIRESVEEVLAFIQRDVRLNGLRQVETPVSPEQEAIHHGHSSSSPLAAGEDAPFRWDHVRVKLKKEIVTLGIPSVSPIERVGTYVSPEEWNELISDPETVVIDVRNTYETRIGKFKGAVDPCTTAFRNFPSWVENQFALKQEGNETQAKVEKEDFSEITHKEDKAEKPKTLPRIAMYCTGGIRCEKASSLLLSQGFEEVYHLKGGILKYLEEVPKTESLWEGECFVFDKRVSVEHGLAQGTHKLCYGCKQPISDEDMEAPEYEYGVSCPYCYSKKSEEEKERARARQTQFEEWGVIGGPDKGRRPATKPDSPRKKINAKLGSSI
What are the official names of this protein?
Rhodanese-like domain-containing protein 7, Sulfurtransferase 7, AtStr7.
Protein: SPRN_SHEEP
Sequence: MNWAAAVCWALLLAATFLCDGSAAKGGRGGARGSARGGRGAARVRVRPAPRYAGSSVRAAAGAAAGAAAAAGVAAGLAAGSSWRRAAGPAELGLEDAEDGAPGSNGTGRGVYSYWAWTSGAGPTGHRHLCPLLGGALGALRLLRP
What is the function of this protein?
Prion-like protein that has PrP(C)-like neuroprotective activity.  May act as a modulator for the biological actions of normal and abnormal PrP (By similarity).
What are the official names of this protein?
Shadow of prion protein, Protein shadoo.
What is the protein family that this protein belongs to?
Belongs to the SPRN family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: PTH_NITWN
Sequence: MRLFVGLGNPGTKYQGNRHNIGFMVVDEIARRHGFAPWRRRFQGEASEGTLDRERVIVLKPATYMNNSGNAVQDAVQFFKLKEADVVVFHDEIELPPAKVRVKVGGGIAGHNGLRSISAHIGNDYRRVRLGVGHPGVKELVHAHVLNDFARSERSWVEALVDTVAENAALLVAAKDSAFQNKVHLAMQAKGFADNGGEDKQN
What is the function of this protein?
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
What are the official names of this protein?
Peptidyl-tRNA hydrolase, PTH.
What is the protein family that this protein belongs to?
Belongs to the PTH family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CH10_SHEB9
Sequence: MNIRPLHDRVIVKRLEVESTSAGGIVLTGSAAEKSTRGEILAVGNGRILENGTVKPLDVKVGDVVIFNEGYGVKKEKIDGQEVLILSEADLMAVVG
What is the function of this protein?
Together with the chaperonin GroEL, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.  GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.
What are the official names of this protein?
Co-chaperonin GroES, 10 kDa chaperonin, Chaperonin-10, Cpn10.
What is the protein family that this protein belongs to?
Belongs to the GroES chaperonin family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DAPA_PROMA
Sequence: MSTVPEISSAPFGRLLTAMVTPFDTAGAVDFALAARLARYLVDQGSDGLIVCGTTGESPTLSWEEQYQLLETVRNAVNGSAKVLAGTGSNSTSEAIHATAKAAEAGADGALVVVPYYNKPPQAGLESHFRAVAQAAPDLPLMLYNIPGRTGCSISPITVQRLMNCSNIVSFKAASGTTNEVTDLRIRCGSRLAIYSGDDGLLLPMLSVGAVGVVSVASHIVGMRLKAMIEAYFAGENSLALSHHEQLQPLFKALFATTNPIPVKAALELIGWPVGAPRSPLLPLENQMKNELMKTISALLQT
What is the function of this protein?
Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
What are the official names of this protein?
4-hydroxy-tetrahydrodipicolinate synthase, HTPA synthase.
What is the protein family that this protein belongs to?
Belongs to the DapA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FADA_SHEAM
Sequence: MKQAVIVDCIRTPMGRSKGGVFRNVRAETLSAELMKALLLRNPGVDPNTIEDVIWGCVQQTLEQGFNIARNASLLAGVPKTAGAVTVNRLCGSSMEALHQASRAIMTGMGDTFIIGGVEHMGHVPMNHGVDFHPGLAANVAKASGMMGLTAEMLGKLHGISREMQDQFAVRSHQRAHAASIEGRFANEIYAIEGHDANGALIKVDYDEVIRPETTLESLAGLRPVFDPANGTVTAGTSSALSDGAAAMLVMEEEKARALGLTIRARVRSMAVAGCDAAIMGYGPVPATQKALARAGLSIQDMDVIELNEAFAAQSLPCVKDLGLMDVVEDKVNLNGGAIALGHPLGCSGARISTTLINLMEHKDATLGLATMCIGLGQGIATVFERV
What is the function of this protein?
Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
What are the official names of this protein?
3-ketoacyl-CoA thiolase, Acetyl-CoA acyltransferase, Beta-ketothiolase, Fatty acid oxidation complex subunit beta.
What is the protein family that this protein belongs to?
Belongs to the thiolase-like superfamily. Thiolase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YQO5_SCHPO
Sequence: MSTNPNAGIQPLTNSISQSASAHPELYHTTSHESVSTYQLQSQLSHSATSNLSTAANFHTRPPIANDENAQNLSTVNSSHSSELSKANLVDVEKCIQDPLLQIFPTVEDPDRFVFSIDPKSPLIAVNWPFRKKLKITCVYSYVALCSTFASSVFSVPAEAITTIFHISLTVSLLTMTVFLCGYIAGPIVWAPLSELSGRKLPLLIGMFGFGIFNISVAVAKDIQTIMMCRFFSGFFASAPLTVVAAAFADMYSNKHRGTAITIFAALVFDGPLVSPIIGGFLTKSYLGWRWTEYITSFMGFFALVIVYLFCDETYSKAIIRNKAKEYRAMSGNYFVHAKSEEEVLTVPDVAKNYLLVPMKLLFTEPIVFLITLYSSFVYAILYLLLEAYPIIFSEKRHFSMGVAELPYIGLLVGVFIGSAINISFEPWYYRRCLALGGKPDPEARLPPMMIGCFMFPAGIFWLSWSGYYSYVHWIVPTLSGLATGCGILLIFLQCLNYLIDAYLFRAASAVAANTIMRSAMAAGFPLFAVQMFHNMGVGWAGSLLGFIAVALIPMPFAFFFFGRKIREKSKMAVVL
What are the official names of this protein?
Uncharacterized transporter C569.05c.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. CAR1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum. Golgi apparatus. Membrane; Multi-pass membrane protein.
Protein: ACTP4_ACTEQ
Sequence: MSRLIIVFIVVSMICSATALPSKKIIDEDEKDEKRSVAVAGAIIKGAALTFNVLQTVLKALGDISRKIAVGVDNESGKTWTALNTYFRSGTSDIVLPHKVPHGKALLYNGQKDRGPVATGAVGVLAYAMSDGNTLAVLFSVPYDYNWYSNWWNVRIFKGRRRADQRMYEQLYYYLSPFRGDNGWHERHLGYGLKSRGFMNSGGQAILEIHVTKA
What is the function of this protein?
Pore-forming protein that forms cations-selective hydrophilic pores of around 1 nm and causes cytolysis.  Pore formation is a multi-step process that involves specific recognition of membrane sphingomyelin (but neither cholesterol nor phosphatidylcholine) using aromatic rich region and adjacent phosphocholine (POC) binding site, firm binding to the membrane (mainly driven by hydrophobic interactions) accompanied by the transfer of the N-terminal region to the lipid-water interface and finally pore formation after oligomerization of monomers.
What are the official names of this protein?
DELTA-actitoxin-Aeq1c, DELTA-AITX-Aeq1c, Equinatoxin IV, EqT IV, EqTIV, Equinatoxin-4.
What is the protein family that this protein belongs to?
Belongs to the actinoporin family. Sea anemone subfamily.
What are the subcellular locations of this protein?
Secreted. Nematocyst. Target cell membrane. Note=Forms an alpha-helical membrane channel in the prey.