PharMolix/UniProtQA huggingface dataset:
Protein: RPOD_SHEVD
Sequence: MEHTPQSQLKLLLAKGKEQGYLTYAEVNDHLPADMVDADQIEDIVQMINDMGIRVYEQAPDADEIMMTEDSTDDDAAEEAAAALATVEAELGRTTDPVRMYMREMGTVELLTREGEIVIAKRIEEGIYTVQASVAEYPPAIASILDQFDRYEAEEVRLSDIISGFIDPNAADIAPTATHIGSDLSQSERDKDDSKDDSKDDDEDEEEEGPKGPDPEESKERFTQLREVHENTLKIIADKGRGHPEATVALFEIGELFKEFRLMPKQFDRLVKNMRATMDKVRVQERLIMKLCVEQAKMPKKNFVKGYTADESSIAWFDTELASKKPYAEGLKMIEPDVRRCRFKLDIIEKETGLAIASIKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATGESLRNATHEVLAGLTAREAKVLRMRFGIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEILKSFLDE
What is the function of this protein?
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.  This sigma factor is the primary sigma factor during exponential growth.
What are the official names of this protein?
RNA polymerase sigma factor RpoD, Sigma-70.
What is the protein family that this protein belongs to?
Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: BIOF1_BACVZ
Sequence: MKEFEFLKAELDKMKENKTWQQMKQIETKQGPSVEVKGENVIQLSSNNYLGLTSHPRLVEAAKRAAEEFGAGTGSVRTIAGTFTMHNELEKKLANFKKTEAALVFQSGFTTNQGVLSSILTKEDIVISDELNHASIIDGIRLTKADKKVYRHVDMDDLERVLKKSMNYRMRLIVTDGVFSMDGNIAPLPDIVKLAEAYDAFVMVDDAHASGVLGKNGRGTVNHFGLDGRVHIQVGTLSKAIGVLGGYAAGSQVLIDYLRHKGRPFLFSTSHPPAVTAACIEAIDVLLEEPEHMEKLWENTAYFKDKLVQMGLTLTKSETPIVPILIGEEEKAQALSDLLLTRGVFAQSIVYPTVAQGKARIRTIITAEHTNEELDRALEVIRSAAKELQLV
What is the function of this protein?
Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
What are the official names of this protein?
8-amino-7-oxononanoate synthase 1, AONS, 7-keto-8-amino-pelargonic acid synthase, 7-KAP synthase, KAPA synthase, 8-amino-7-ketopelargonate synthase, Alpha-oxoamine synthase.
What is the protein family that this protein belongs to?
Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
Protein: RS13_BRUSI
Sequence: MARIAGVNIPTNKRVNIALQYIHGIGPKFAREIVTKVGIADDRRVNQLSDAEVLQIREAIDADYQVEGDLRREVSMNIKRLMDLGCYRGLRHRRSLPVRGQRTHTNARTRKGPAKAIAGKKK
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: MO3_MOROL
Sequence: NRLCCSQYGFCGTTSEYCSRANGCQSNCWGR
What is the function of this protein?
Chitin-binding protein which functions in defense against chitin-containing fungal pathogens.
What are the official names of this protein?
Morintide mO3, Morintide hevein-like peptide 3, Mo-HLP3.
Protein: Y368_STRE4
Sequence: MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFTGDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF
What is the function of this protein?
Binds to DNA and alters its conformation.  May be involved in regulation of gene expression, nucleoid organization and DNA protection.
What are the official names of this protein?
Nucleoid-associated protein SEQ_0368.
What is the protein family that this protein belongs to?
Belongs to the YbaB/EbfC family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid.
Protein: INT7_HUMAN
Sequence: MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEAVVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDEFVKRIFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVFAAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLLQQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKNDPRKAVKRLAIQDLKLLANKTPHTWSRENIQALCECALQTPYDSLKLGMLSVLSTLSGTIAIKHYFSIVPGNVSSSPRSSDLVKLAQECCYHNNRGIAAHGVRVLTNITVSCQEKDLLALEQDAVFGLESLLVLCSQDDSPGAQATLKIALNCMVKLAKGRPHLSQSVVETLLTQLHSAQDAARILMCHCLAAIAMQLPVLGDGMLGDLMELYKVIGRSATDKQQELLVSLATVIFVASQKALSVESKAVIKQQLESVSNGWTVYRIARQASRMGNHDMAKELYQSLLTQVASEHFYFWLNSLKEFSHAEQCLTGLQEENYSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLRIDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLASRYGDLYQASFDADSATLRNVELQQQSCLLISHAIEALILDPESASFQEYGSTGTAHADSEYERRMMSVYNHVLEEVESLNRKYTPVSYMHTACLCNAIIALLKVPLSFQRYFFQKLQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRKIQSVCLNVSSTLQSKSGQDYKIPIDNMTNEMEQRVEPHNDYFSTQFLLNFAILGTHNITVESSVKDANGIVWKTGPRTTIFVKSLEDPYSQQIRLQQQQAQQPLQQQQQRNAYTRF
What is the function of this protein?
Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.  The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable).  Plays a role in DNA damage response (DDR) signaling during the S phase (PubMed:21659603).  May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex (PubMed:23904267).
What are the official names of this protein?
Integrator complex subunit 7, Int7.
What is the protein family that this protein belongs to?
Belongs to the Integrator subunit 7 family.
Protein: GLYA_SHIFL
Sequence: MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEKQAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERIKGKVLDICARYPVYA
What is the function of this protein?
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier.  This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules.  Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
What are the official names of this protein?
Serine hydroxymethyltransferase, SHMT, Serine methylase.
What is the protein family that this protein belongs to?
Belongs to the SHMT family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ENO_YERPP
Sequence: MSKIVKVIGREIIDSRGNPTVEAEVHLEGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNGPIAQAVIGKDAKDQANIDKIMIDLDGTENKSQFGANAILAVSLAAAKAAAASKGMPLYEHIAELNGTPGKFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEAVRIGSEVFHHLAKVLKAKGLNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEDLTKQYPIVSIEDGLDESDWAGFKYQTEVLGDKIQLVGDDLFVTNTKILKEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGDRAPFNGLKEVKGQ
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: RBL_MAIZE
Sequence: MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQLGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVPGDPDQYICYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYSKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRACYECLRGGLDFTKDDENVNSQPFMRWRDRFVFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTTLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIFFTQDWVSMPGVIPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAAANRVALEACVQARNEGRDLAREGNEIIKAACKWSAELAAACEIWKEIKFDGFKAMDTI
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process.  Both reactions occur simultaneously and in competition at the same active site.
What are the official names of this protein?
Ribulose bisphosphate carboxylase large chain, RuBisCO large subunit.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO large chain family. Type I subfamily.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: SPEA_SHEFN
Sequence: MSDWSIEDARSGYNVTHWSQGFYGIREDGEVTVSPNPQNPDHKVGLNELAKSMVEAGVSLPVLVRFPQILHHRVESLCEAFNDAIKKYDYQNDYLLVYPIKVNQQKTVVEEILASQKSKEVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDKEYIRLALIGEKLGHKVYIVLEKMSELKMVLIEAEKLGITPRLGLRVRLAFQGKGKWQASGGEKSKFGLSAAQVLKVIAELKSANMLDSLQLLHFHLGSQIANIRDIRQGVSEAGRFYCELRQLGASIDCFDVGGGLAVDYDGTRSQSNNSMNYGLNEYANNIVNVLTDLCNEYEQPMPRIISESGRHLTAHHAVLITDVIGTEAYQPENIQEPSEDAPQLLHNMWQSWLEISGRYDQRAIIEIYHDSQSDISEAHSLFAVGQLSLADRAWAEQANLRVCHEVKGLLSNNNRYHRPVIDELNEKLADKFFVNFSLFQSLPDAWGIDQVFPVLPLSGLDKAPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPAWSADSPYLIGFFMVGAYQEILGDMHNLFGDTNSAVVRIDERGLSQIESVLEGDTVADVLRYVNLDAVDFMRTYEELVNQHIVEEERASILEELQLGLKGYTYLEDF
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: GRPE_SALHS
Sequence: MSSKEQKTPEGQAPEEIIMDQHEEVEAVEPNDSAEQVDPRDEKIANLEVQLAEAQTRERDTVLRIKAEMENLRRRTEQDIEKAHKFALEKFVNELLPVIDSLDRALEVADKANPDMAAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMVESEEVPAGNVLGIMQKGYTLNGRTIRAAMVTVAKAK
What is the function of this protein?
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE.  It is the nucleotide exchange factor for DnaK and may function as a thermosensor.  Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex.  GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle.  Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.
What are the official names of this protein?
Protein GrpE, HSP-70 cofactor.
What is the protein family that this protein belongs to?
Belongs to the GrpE family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PLPL_PICGU
Sequence: MTSSTPLYDENEDYIDENHINTFAKALLWEDDDHDGLASPPLPAYEGDKLAEVNAEELSSVLTPEPNNESEKSRPEFVVSHNDWYPINAPEKSKAKADAKGRKKRASTRDEFRSSAAYTLLRWPFLIIITVWILLLCILYTVVRAYVALSEYMLTWVGERKVLRNKLRASKTYEEWIENALELDRYLHLDKWSSIPRFSYYDYRTVKRTTSKLRMLRMRGMDEELMVFLQGCLKKNFAGIENRQLYAHRYYGTKNVVHVYIDEVVASIDHVTESENITPEDKRRFFRSVSRNYGRTALCLSGGACFAYTHFGIVKALLDNDLLPSIITGTSGGGLVAALACTRTDDELKQLLVPRLARKITACEDPWYVWIPRWWRTGARFDSTAWARKSNYFTLGSLTFQEAYHRTGRRLNISTVPADPHSPVILCNNITAPNCIIWSCLLASSAVPGILNPVVLMMKDSKKNTIVPFSLGSKWKDGSLRTDIPIDALKTYYNVNFTVVSQVNPHISLFFFAPKGSVGRPVASSRRKTRREKYASLRGGFIATALEHLFKLEIKKWLEMIKTLDLLPRLSESDWSSIWLQRFTGSITIWPRNNFRDFWYILSDPSEEGLGEMIRKGERYMFPKILFLKHRLSIENAIERGRTKSKLSTAHLEHSPRFSGTPEFAGPEFQLQTVHYDDDYDSESSAEETLSPGFSQGTHAVLTDESDDDSSDDEIDD
What is the function of this protein?
Probable lipid hydrolase.
What are the official names of this protein?
Patatin-like phospholipase domain-containing protein PGUG_03164.
What is the protein family that this protein belongs to?
Belongs to the PLPL family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: RECR_HAEIG
Sequence: MQSSPLLEHLIENLRCLPGVGPKSAQRMAYHLLQRNRSGGMNLARALTEAMSKIGHCSQCRDFTEEDTCNICNNPRRQNSGLLCVVEMPADIQAIEQTGQFSGRYFVLMGHLSPLDGIGPREIGLDLLQKRLVEESFHEVILATNPTVEGDATANYIAEMCRQHNIKVSRIAHGIPVGGELETVDGTTLTHSFLGRRQID
What is the function of this protein?
May play a role in DNA repair.  It seems to be involved in an RecBC-independent recombinational process of DNA repair.  It may act with RecF and RecO.
What are the official names of this protein?
Recombination protein RecR.
What is the protein family that this protein belongs to?
Belongs to the RecR family.
Protein: SRK2A_ARATH
Sequence: MDKYELVKDIGAGNFGVARLMKVKNSKELVAMKYIERGPKIDENVAREIINHRSLRHPNIIRFKEVVLTPTHLAIAMEYAAGGELFERICSAGRFSEDEARYFFQQLISGVSYCHAMQICHRDLKLENTLLDGSPAPRLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKMADVWSCGVTLYVMLVGAYPFEDQEDPKNFRKTIQKIMAVQYKIPDYVHISQDCKNLLSRIFVANSLKRITIAEIKKHSWFLKNLPRELTETAQAAYFKKENPTFSLQTVEEIMKIVADAKTPPPVSRSIGGFGWGGNGDADGKEEDAEDVEEEEEEVEEEEDDEDEYDKTVKEVHASGEVRIS
What are the official names of this protein?
Serine/threonine-protein kinase SRK2A, Arabidopsis protein SK1, OST1-kinase-like 7, SNF1-related kinase 2.4, SnRK2.4.
What is the protein family that this protein belongs to?
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Protein: SYGB_DICT6
Sequence: MGKNFLLEIGTEEMPAHFIDPAIRQMYDFSLEYFKNKKISLESVKIWATPRRLVVYIENLGEKQEAQEEEIRGPAAHIGYKDGMWTEVAKRFVEQYGASLEDLHIEETPKGKYIFLRKVKEGMNTLEILPDYITSLLKSIRFPKMMKWGDVDFYFGRPIRWIVALYGDTEIEVEIAGVKSSRYSRPPRFLPQIPIEIRDADSYLNVMRENYIIVDQEERKNEILKQINKIANENSFILDYEDDLLKEVNYLVEYPTALLGEFDKKYLALPEVVLIITMEKKQRYFPLRDADGNLTNKFIVIRNGTDNYKDIVIQGNEKVLKARLSDAEYYYHEDTKHPLEKYTEKLSGIIFQEQLGTIKDKVERVRILVREIANILGLSSEENKILERSVNLYKADLGTLMVSEYPELHGIMGRIYAKISGEKDPIPEVIGEYIYPRTLDDRLPSNFLASILGIADRIDSLTGYFALDLFPTGSEDPIGLRRISGGLLRLLLESSLKLNLRNLFVKSFEIYNFGEKYPLSQIDKGMGFIGQRLRNLLLDRYSIDIVDAVMEVGYDEMWRLKRRLDFISKFKEKESYEKLKKALNRLYRILPKDFTPKEVSENLLSSPFEKKLYEDYLKIKNEIFNDILEGNYEVLLSYDFLNEFSDDIEKFFDNVLVMSPNEDERINRLSLLSLIKLLFWEILDWSRLS
What are the official names of this protein?
Glycine--tRNA ligase beta subunit, Glycyl-tRNA synthetase beta subunit, GlyRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NUSG_LIBAS
Sequence: NQVEAAVQRPVSSVFFEVGERVCVSDGPFASFNGIVKNVDEEKSRVHVEVVIFGRVTPVELAYNQVEKIV
What is the function of this protein?
Participates in transcription elongation, termination and antitermination.
What are the official names of this protein?
Transcription termination/antitermination protein NusG.
What is the protein family that this protein belongs to?
Belongs to the NusG family.
Protein: IACD_PESFW
Sequence: MAQQKVIKYTVEHNRKDGVSEEDFIEWFTNTLIPQMVPVMQKNNILKYAVHKTDHQISTAFQSQVDKVRPGWVVSKCDLILEHWVNDLGDIMKLSQDPEWAAALKDQDVWMDNSKSNIHIGYDTIYIEDGTITNVPRK
What is the function of this protein?
Dehydratase; part of the gene cluster that mediates the biosynthesis of iso-A82775C, a enylepoxycyclohexane and biosynthetic precursor of the chloropestolide anticancer natural products (PubMed:29384350).  Within the cluster, the prenyltransferase iacE prenylates siccayne to generate pestalodiol E, using dimethylallyl diphosphate (DMAPP) as cosubstrate (PubMed:29384350).  The probable oxidoreductase iacF is then involved in the epoxidation of pestalodiol F to pestalodiol F, which is further converted to pestalofone A by the short-chain dehydrogenase/reductase iacG (PubMed:29384350).  Iso-A82775C is subsequently generated from pestalofone A by the short-chain dehydrogenase/reductase iacC (PubMed:29384350).  Iso-A82775C is further condensed with maldoxin via a Diels-Alder reaction to produce the anticancer natural products chloropestolides A to E (Probable).
What are the official names of this protein?
Dehydratase iacD, Iso-A82775C biosynthesis cluster protein D.
What is the protein family that this protein belongs to?
Belongs to the tpcK family.
Protein: OBG_CROS8
Sequence: MKFVDEATILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGDVWLEADENLNTLIDYRFEKSFRAERGQNGQSRDCTGKRGKDVTIKVPVGTRVIDQGTGETMGDMTKHGQRLMVAKGGWHGLGNTRFKSSVNRTPRQKTMGTPGEKRDLQLELMLLADVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLIEGAAEGAGLGIRFLKHLERCRVLLHLIDLDPIDGSDPAENARIIVGELEKYSEKLASKPRWLVFNKIDLLSREEAEAKAKAIADALGWEEKYYLISAASQMNVKDLCWDVMHFIIENPVVHEEEAKQPEKVEFMWDDYHRQQLEEMEAEAEEEWDDDWDEDDDEGVEIVYQR
What is the function of this protein?
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate.  Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
What are the official names of this protein?
GTPase Obg, GTP-binding protein Obg.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBD_CHAGL
Sequence: MTIAIGKSSKEPKGLFDSMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWLTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVAFHGAFGLIGFMLRQFEIARSVQLRPYNAIAFTGPIAVFVSVFLIYPLGQSGWFFAPSFGVAGIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTIFEDGDGANTFRAFNPTQAEETYSFVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAVGVVGLAVNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLVFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: FENR1_LISIN
Sequence: MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPDVGGKVRYFFPEKIIRDIGGIPAITGANLVANLKEQAETFHPTIVCNERVVDVTKLTDGVFQLTSHNGSIHFSKTVVIATGSGTFEVNKLEAMHVDDFPLAINYDVKNLEQFRDKIVTVSGGGNSAIDWAQTLEPIAKKVHLIYRGEDFKAHEESVRELKNSRVEIHIHHEIKELIGANNQLASIKICCNQTQVTKTIETEALFINHGVKVDLGTMAEWGFELADFGIVVDDEMKTTVPGIFACGDSATYSRKIRIIAAGLHEGPIAINSAKKYLEPTARDEAMISTHHESFIG
What are the official names of this protein?
Ferredoxin--NADP reductase 1, FNR 1, Fd-NADP(+) reductase 1.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: PSB_FERPA
Sequence: MIHDKVFKGTTTVGLVCKDGVVLATEKRATMGNFIASRRAKKIYKITDRIAMTTAGSVGDAQFLARLIKVETNLYTIRKEEEPTVKAVATLVSNLLNSVRYFPYLVQLLIGGVDKTGAKIYSIDPIGGAIEEIDIVATGSGSPMAYGVLEDNYRKDINVDEAVELAIRAIYSAMKRDSASGDGIDVVKITEKEYVELTPEEIEAILEKLR
What is the function of this protein?
Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
What are the official names of this protein?
Proteasome subunit beta, 20S proteasome beta subunit, Proteasome core protein PsmB.
What is the protein family that this protein belongs to?
Belongs to the peptidase T1B family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: EHF_HUMAN
Sequence: MILEGGGVMNLNPGNNLLHQPPAWTDSYSTCNVSSGFFGGQWHEIHPQYWTKYQVWEWLQHLLDTNQLDANCIPFQEFDINGEHLCSMSLQEFTRAAGTAGQLLYSNLQHLKWNGQCSSDLFQSTHNVIVKTEQTEPSIMNTWKDENYLYDTNYGSTVDLLDSKTFCRAQISMTTTSHLPVAESPDMKKEQDPPAKCHTKKHNPRGTHLWEFIRDILLNPDKNPGLIKWEDRSEGVFRFLKSEAVAQLWGKKKNNSSMTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNARGWRENEN
What is the function of this protein?
Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation.  May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades.  Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.  Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter.  May contribute to development and carcinogenesis by acting as a tumor suppressor gene or anti-oncogene.
What are the official names of this protein?
ETS homologous factor, hEHF, ETS domain-containing transcription factor, Epithelium-specific Ets transcription factor 3, ESE-3.
What is the protein family that this protein belongs to?
Belongs to the ETS family.
What are the subcellular locations of this protein?
Nucleus.
Protein: CENPM_CHICK
Sequence: MAVLRPFDKLPELNSATILLVGAEGGPQQQLAEAMLREKKDFNINIHLASSLPLPSERDHLRPRIDLIAFVIDIKSKYSLKNVQASLAYVDVRFFLGKVCFLVTGVGRANNCSVEMNAIWKLGEDYCSPVIFCELELEGIRVATAQRLLRMLQICAGRVPGVSALYFSLLMRNSAGD
What is the function of this protein?
Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation.
What are the official names of this protein?
Centromere protein M, CENP-M.
What are the subcellular locations of this protein?
Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres.
Protein: RL51_ORYSI
Sequence: MGGFVKTQKTNAYYKRFQVKFKRRRQGKTDYRARIRLTNQDKNKYNTPKYRFVVRFTNKDITAQIVYATIAGDIVMAAAYSHELPRYGLEVGLTNYAAAYCTGLLLARRVLKLRGLDQEYEGNIEATGEDYYVEPADERRPFRALLDVGLIRTTTGNRVFGALKGALDGGLDIPHSDKRFAGFKKDEKQLDSDIHRKYIYGGHVADYMRSMAEEEPEKFQAHFSEYLKKGIDADGMEALYKKVHAAIRADPTMAKSTKKEPATHKRYNLKKLTYEQRKASLVERLNALNSSAGADDDDEEEDDE
What is the function of this protein?
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.  The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules.  The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain.  The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.
What are the official names of this protein?
60S ribosomal protein L5-1.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: CLPP1_LEIXX
Sequence: MADMGIQPSVFDRLLKDRIIWLGSEVRDENANEIAAKLLLLAAEDSKRDIYLYINSPGGSITAGMAIYDTMQFVPNDIVTVGIGMAASMGQLLLTAGTKGKRYITPNARVLLHQPHGGFGGTASDIRTQAQLILHMKKRLAEITSEATGKTVDQVNADGDRDRWFTAQEALDYGFVDHIRESALLVAGGGGTAPAGK
What is the function of this protein?
Cleaves peptides in various proteins in a process that requires ATP hydrolysis.  Has a chymotrypsin-like activity.  Plays a major role in the degradation of misfolded proteins.
What are the official names of this protein?
ATP-dependent Clp protease proteolytic subunit 1, Endopeptidase Clp 1.
What is the protein family that this protein belongs to?
Belongs to the peptidase S14 family.
What are the subcellular locations of this protein?
Cytoplasm.