PharMolix/UniProtQA huggingface dataset:
Protein: GLMM_MYCUA
Sequence: MGRLFGTDGVRGVANRELTAELALALGAATAQHLASSTGPGRRVAVVGRDPRASGEMLEAAVIAGLTSQGVDALRVGVLPTPAVAYLTGAYDADFGVMISASHNPMPDNGIKIFGPGGHKLDDATENRIESLVAAGPGLRPVGSEIGRVIDAEDAADRYLRHVSKACTTRLDGLTVVVDCAHGAASEVGPRAYRAAGARVIEINADPNGLNINDDCGSTHLEAIRAAVLAHGADLGVAHDGDADRCLAVDANGDLVDGDAIMVVLALAMQEAGELASDTLVTTVMSNLGLHLAMREAGVNVRTTGVGDRYVLEELRAGDYSLGGEQSGHIVMPGLGSTGDGIVTGLRLMTRMVATGASLAALASRMQTLPQVLINVQVTDKATAAAAPSVQAAVDRAETELGDTGRILLRPSGTEPLIRVMVEAADEEAAHRLATSVADAVSAAG
What is the function of this protein?
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.
What are the official names of this protein?
Phosphoglucosamine mutase.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: LEUC_SHEB2
Sequence: MTNAKTLYQKVWDAHIVTAPEGEAPVIYVDRHLVHEVTSPQAFSGLKVAGRKLRAPEKTFATMDHNTSTRSASLDALSPMARTQVETLAQNCKDFGVRLYDIHHPNQGIVHVMGPELGITLPGTVIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLRQLKAKTMKIEVRGHVTDGVTAKDIVLAIIGKIGMDGGTGYVVEFCGEAIEALSMEGRMTVCNMAIEMGAKAGMVAPDQTTFDYLAGREFAPKGEDWTEAVAYWKAIKTDDGAVFDAVVELDAADIAPQLTWGTNPGQVVAIDGKVPDPINEANPSTRASMEKALEYIGLSAGTPMTDISINKVFIGSCTNSRIEDLRSAAVHAKGRKVASGVTAIVVPGSGQVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNDDRLEAGDRCASTSNRNFEGRQGRGSRTHLVSPAMAAAAAVAGHFVDIRKPY
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase large subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
Protein: DNLJ_OENOB
Sequence: MNPADQFTPIEDLTFTQAQAEIRDLSDELTKWGREYYEEDNPSVEDYVYDAHYARLVALEKAYPSLAMPDSPTQHVAAGNQTKNDSRGLQKVVHPVPMLSLGDVFSIQELLDWDLVTTKNAGSQQKYNLELKIDGLAISLRYENGRLIQASTRGDGSIGENVTDNVKTITEIPKVLNEPLTIEVRGEIYMRKEAFADLNQQRDEEGKTIFANPRNAAAGSLRQLDPKITAKRHLSSFIYYTAQNDVLGVNTQSDVLERFRQLGFPVNSSNKVIDRMTEVKDYIDEYTIKRDNLPYGIDGVVVKVNDLDVENELGNTVKIPRWSIAYKFPPEEALTVVRDITWTVGRTGVVTPTAIMDPVFLAGTKVKRASLHNPDYLQEKDVRIGDTVTLHKAGDIIPEVGQVILKKRPADAQAYPIPVYCPSCKSKLVHVQGEVALRCINPECPAQIKEGLIHFASRNAMNIDGLGPRVVEQLLSKNLIRKISDLYALTESQLTTLDKFADLSSKNLIQAIDRSRQNSVERLITALGIRGVGAKAAKVLAAHFKNLRNLQNAGAEEIAEIDGVGQVMADAIRQYFNSESVASLINELENFQVNFDYLTTSTVDEKNYFFNKRIVLTGKLIHWTRPQMQAWLEEHGANVSSSVSSKTDLLIAGSDVGSKLERANKLGIKVINEQDFINLSNAKK
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: UBIA_FRAP2
Sequence: MQNNTKFKAYIMLMRLHRPIPILLILWPTLTALVLASHGIPDIKYLIVFTIGVVVMRTVGCIVNDIADIDFDKYVERTNTRPLTSGKLSVKNALYLCLALTIIAFICVLFLNLYTILLSFVALFLAVLYPFCKRFFAIPQLILGLAFNFGIFMAFSAIENQIPLEAWIFYLSTICWTIAYDTIYALADRDFDLEIGIKSSAVLFGDKVFKYIFLFNFISLILLIALGIYLSFNIIFYIGVIISAFLFIRNYFLYKKLGITNCIKAFSDNHWIGLIIFILVVIQYL
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DLTC_STRZP
Sequence: MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVEIENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA
What is the function of this protein?
Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA).  The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA.  The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD.  D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall.
What are the official names of this protein?
D-alanyl carrier protein, DCP, D-alanine--poly(phosphoribitol) ligase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the DltC family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MBD2_ARATH
Sequence: MSMSQSRAVQRSSSPNEDRGENQLVVYDLKGNDDTEEEVLPVQSQPLSSRTQCPSIGAFTVQCASCFKWRLMPSMQKYEEIREQLLENPFFCDTAREWKPDISCDVPADIYQDGTRLWAIDKPNISRPPAGWQRLLRIRGEGGTRFADVYYVAPSGKKLRSTVEVQKYLNDNSEYIGEGVKLSQFSFQIPKPLQDDYVRKRPARLLDSIDNTNTPVAKEANPLAWISPDDHISLQLGTPTESGLNNSHYQPSKKKKTSTLSIFGSNDELADR
What is the function of this protein?
Probable transcriptional regulator.
What are the official names of this protein?
Methyl-CpG-binding domain-containing protein 2, AtMBD2, MBD02, Methyl-CpG-binding protein MBD2.
What are the subcellular locations of this protein?
Nucleus. Note=Not present in chromocenters and the nucleolus.
Protein: RS16_BRUMB
Sequence: MALKIRLARAGSKKRPYYHVVVADVRAPRDGRFIETVGSWNPVLPKDAERVKLDAERIQHWIAQGAQPTDRVLRFLDQAGIAKRPSRNNPTKGEPGKKAQERLALAKQAEEEAAAKAAEAASE
What are the official names of this protein?
30S ribosomal protein S16.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bS16 family.
Protein: DPCKG_SULIN
Sequence: MEIRDNNKVNLCFAFDNLRKELSRPYGILFTNNKLFLDFVSKSIQQGFKVITVGDYVSRVLEENGIIPFLEVIDGKTKRSIPQRTIVKNKEYRVTNEAGKIRFEIFEIMENILKDRDGGVVFVNGEEDLLVIPVTLSADNGDIVIYGQPNAGAVVIIVNEMIRWRVRDILEKAVVKEC
What is the function of this protein?
Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
What are the official names of this protein?
GTP-dependent dephospho-CoA kinase, Dephospho-coenzyme A kinase, DPCK.
What is the protein family that this protein belongs to?
Belongs to the GTP-dependent DPCK family.
Protein: GSTM1_RAT
Sequence: MPMILGYWNVRGLTHPIRLLLEYTDSSYEEKRYAMGDAPDYDRSQWLNEKFKLGLDFPNLPYLIDGSRKITQSNAIMRYLARKHHLCGETEEERIRADIVENQVMDNRMQLIMLCYNPDFEKQKPEFLKTIPEKMKLYSEFLGKRPWFAGDKVTYVDFLAYDILDQYHIFEPKCLDAFPNLKDFLARFEGLKKISAYMKSSRYLSTPIFSKLAQWSNK
What is the function of this protein?
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.  The olfactory GST may be crucial for the acuity of the olfactory process (PubMed:8110735, PubMed:8664265).  Participates in the formation of novel hepoxilin regioisomers (By similarity).
What are the official names of this protein?
Glutathione S-transferase Mu 1, GST 3-3, GSTM1-1, Glutathione S-transferase Yb-1, GST Yb1.
What is the protein family that this protein belongs to?
Belongs to the GST superfamily. Mu family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VF354_ASFM2
Sequence: MALTTHSGKLIPELQFKAHHFIDKTTVLYGPSKTGKTVYVKHIMKILQPHIEQILVVAPSEPSNRSYEGFVHPTLIHYRLWLADKQKKNDNKGAERFLEAIWQRQTMMSSIYSRVNNIDMLKTLYHKLPIDIQQKENKNIAKVECLKAEQTDQKKEEKITSLYQQLLKKIIIQNIHMYKNLCLTEDEKFTLNYINLNPRLLLILDDCAAELHPLFTKEIFKKFFYQNRHCFISMIICCQDDTDLPANLRKNAFVSIFTNASICMSNFSRQSNRYSKQDKEYVEEISHIVFKGYRKLVYIREDENRQHFYHSTVPLPTAFSFGSKALLKLCKAVYSKEVVIDKSNPYWSKFRLNF
What are the official names of this protein?
Uncharacterized protein B354L, pB354L.
What is the protein family that this protein belongs to?
Belongs to the asfivirus B354L family.
Protein: BCH2_YEAST
Sequence: MSFLWGSTKSKKGKNKKAAGSLPSGVVPQQRVKPTRKNVPIDYPRTLEKVHGESLIFRTSLLSELVSTGKSGIGPPDLIHCTELDKFHDEKIGEFFYITGIDASSVSMPIAFLKLIKWNDGKKLKSASLKNDDITTYCTFNIFQKLDIRLRYESEDVYQVNIVDCLNGNNEIPLSDLIWEETFVSCCIRSVIINSDFERKIPGLVELPFVFENRCASDYKRVIDSLCKFLPRFLECGWDSTKSVYATILNNYLTESLLVFLSITPEFITDYAIQVLDNLMTNDPSNSRYYAIVIISIMERSNDRDVEMIKRIHEILDLLLPVLYGLPSDEPYISDLINCITDVLSIQARFLLNNNDYELSLSISTLATNLSSDNFESWYLLSKGYIFSQQYDKALLSINSMPCLAEYDIVKQAQINAFKFYMNYYKAPLCHSREHCTMTSHELNHLMNIMHYENELELKTIIFGRTVMPNESKYGCIEEIWNKSCLELGPICGPQSDNLINFVSQQEVNTVGDMLLLKRSKETRQESWFIKQVRLLLMELVARIGWNALLQLRSDVFVMESKFKMIESSDKLSTELRQKRLCQRWFDAMFLDVYEDLSISTSSQENKATAKYSGLEWELLGLTLLRVSDLPDAVACLRTSILARFDPISCHHLLNFYLTMDFNDEFMRRFDVDIILDLLVKLISFRIRFYDRFQIFSLQVLRKLEGQLGSEIIKNKIINSPYGQAGITSVIDYMLECLSKNRNEACLAYERPLPDLPSTIKPLAD
What is the function of this protein?
Member of the CHS5-ARF1P-binding proteins (CHAPS) which mediates export of specific cargo proteins, including chitin synthase CHS3.
What are the official names of this protein?
Protein BCH2, BUD7 and CHS6 homolog 2.
What is the protein family that this protein belongs to?
Belongs to the CHAPS family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Note=Trans-Golgi network location requires interaction with CHS5 and with myristoylated GTP-bound ARF1 for the recruitment to the membranes.
Protein: MURB_STAAE
Sequence: MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPTKNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAGSGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQGSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQPLEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYENLIHYVQKTVKEKFGIELNREVRIIGEHPKES
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL10_DANRE
Sequence: MGRRPARCYRYCKNKPYPKSRFCRGVPDPKIRIFDLGRKKAKVDEFPLCAHMVSDEYEQLSSEALEAARICANKYMVKTCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSVRTKAQNKEHVIEALRRAKFKFPGRQKIHVSKKYGFTKFNTCDFDNMLAEKRLIPDGCGVKYIPSRGPLSRWKALHAN
What is the function of this protein?
Component of the large ribosomal subunit (Probable).  Plays a role in the formation of actively translating ribosomes (PubMed:25316788).  Plays a role in the embryonic brain development (PubMed:25316788).
What are the official names of this protein?
60S ribosomal protein L10, Protein QM, Ribosomal protein L10.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: CRCB_POLAQ
Sequence: MWLSILAIFCGAGLGALLRTGFNLLSVGVASVIPLGTLISNMVGGYLIGIALAFFGNNPHLSPEWKLLIITGFLGGLTTFSSFSAEVVTMIQRGEFTWALGTALLHLVGSLVLTLLGIWTYQAIK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RE104_SACPS
Sequence: MSTNKEEEHQIVCTQDFLRQYYVSESVSIQFGLNNKTIRTINEEEFNNAAMCIMTRTNYPESTLKRSASTYLLNSYHKKPATLSLPFVFGDTINLSEDMEDNNENNLLYSDTLYGDDSLTQRGDQVVYKIDTQEEDSSFTLLQSEANETRPLSSSSTPQILQSDYSVVMQEGQTSNGSIFQFSSP
What is the function of this protein?
Potential transcriptional regulator that is required to activate expression of a number of early meiotic genes including HOP1.
What are the official names of this protein?
Meiotic recombination protein REC104.
Protein: CLP1L_MOUSE
Sequence: MWSGRSSFTSLVVGVFLVYVVHTCWVMYGIVYTRPCSGDSNCIQPYLALRPKLQLSVYTTTRSSLGAENNVDLILNVEDFDVDSKFERTVNVSVPKKTRNNGTLYAYIFLHHAGILPWQDGKQVHVVSTLTTYMIPKPEEINLLTGESATQQQIEAEKKPSNALDEPVSHWRPRLTLNVMVDDFVFDGSSLPADVHRYMKMIQLGKTVHYLPILFIDQLSNRVKDLMVINRSTTELPLTVSYDKISLGRLRFWIHMQDAVYSLQQFGFSEKDADELKGIFVDTNLYLLALTFFVAAFHLLFDFLAFKSDISFWKKKKSMIGMSTKAVLWRCFSTVVIFLFLLDEQTSLLVLIPAGVGAAIELWKVKKALKITVAWRGLRPVFQFGTHSESERKTEKYDAQAMKYLSYLLYPLCVGGAVYSLLNIKYKSWYSWLINSFVNGVYAFGFLFMLPQLFVNYKMKSVAHLPWKAFTYKAFNTFIDDVFAFIITMPTSHRLACFRDDVVFLVYLYQRWLYPVDKSRVNEFGESYEEQPKRKPHPD
What is the function of this protein?
Scramblase that mediates the translocation of glucosaminylphosphatidylinositol (alpha-D-GlcN-(1-6)-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol, GlcN-PI) across the endoplasmic reticulum (ER) membrane, from the cytosolic leaflet to the luminal leaflet of the ER membrane, where it participates in the biosynthesis of glycosylphosphatidylinositol (GPI).  GPI is a lipid glycoconjugate involved in post-translational modification of proteins.  Can also translocate 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) (phosphatidylinositol or PI), as well as several other phospholipids (1,2-diacyl-sn-glycero-3-phosphocholine, 1,2-diacyl-sn-glycero-3-phosphoethanolamine), and N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI) in vitro.
What are the official names of this protein?
Lipid scramblase CLPTM1L, Cisplatin resistance-related protein 9, CRR9p, Cleft lip and palate transmembrane protein 1-like protein, CLPTM1-like protein.
What is the protein family that this protein belongs to?
Belongs to the CLPTM1 family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: HYP1_PISTI
Sequence: MKFAAVVVLAAAAAAVSAETNAQRMARGLPPKAPIRRHGTPADTEKRSHPSSTGGGQCNTGPIQCCNTVATSGSQSGVDELLTLLGLSVPVGTQVGASCSPISAVGTGSGAQCSGQTVCCEQNEWNGLVNIGCMPINLNA
What are the official names of this protein?
Hydrophobin-1.
What is the protein family that this protein belongs to?
Belongs to the fungal hydrophobin family.
What are the subcellular locations of this protein?
Secreted, cell wall.
Protein: ACBP_HUMAN
Sequence: MSQAEFEKAAEEVRHLKTKPSDEEMLFIYGHYKQATVGDINTERPGMLDFTGKAKWDAWNELKGTSKEDAMKAYINKVEELKKKYGI
What is the function of this protein?
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters.  It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor.  It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
What are the official names of this protein?
Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, DBI, Endozepine, EP.
What is the protein family that this protein belongs to?
Belongs to the ACBP family.
Protein: IF3_STRPJ
Sequence: MFFSNKTKEVKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADNANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGDFDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKMDGRQMFMQLAPATDKK
What is the function of this protein?
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
What are the official names of this protein?
Translation initiation factor IF-3.
What is the protein family that this protein belongs to?
Belongs to the IF-3 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MACAP_MOUSE
Sequence: MVLDSGTQVYEQAPPRPPAGSPSQHHKLKPSNGNGPPLYPWPESLGMPLALAVPSALQQQTMWQTFSKLHLEQSSHMRRSESTYSVNSTGRRGRGKAPIGRGCDPGGTLRPAASLPHIAKIRKDVGSSSSKSPCMLVALRPTNMDQEREKFFQSHYTYNPQFEYQEPMPMSVLEKYQEASAQFMNQAVGIIEAVLEKFGTYENFEAATGGQLLTKCQIWSTVRKYMQKEGCVGEIVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRLQYGLQPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLAQYVQDEGVRWEYCVRAKRGQTDTSQPGCFSKDQVYLDGILRILRHRHTIDFQLLTSLGKVSYEDVEQLRPYGVLDNTRVPHFMKDLERYRQQLEHIMTTNRLDEAELGRLLPD
What is the function of this protein?
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function (PubMed:35482892).  Also able to remove the C-terminal phenylalanine residue of alpha-tubulin TUBA8.  Recognizes adjacent tubulin dimers along the same protofilament (By similarity).
What are the official names of this protein?
Microtubule-associated tyrosine carboxypeptidase.
What is the protein family that this protein belongs to?
Belongs to the peptidase MATCAP family.
Protein: GB_HHV1K
Sequence: MHQGAPSWGRRWFVVWALLGLTLGVLVASAAPTSPGTPGVAAATQAANGGPATPAPPPLGAAPTGDPKPKKNKKPKNPTPPRPAGDNATVAAGHATLREHLRDIKAENTDANFYVCPPPTGATVVQFEQPRRCPTRPEGQNYTEGIAVVFKENIAPYKFKATMYYKDVTVSQVWFGHRYSQFMGIFEDRAPVPFEEVIDKINAKGVCRSTAKYVRNNLETTAFHRDDHETDMELKPANAATRTSRGWHTTDLKYNPSRVEAFHRYGTTVNCIVEEVDARSVYPYDEFVLATGDFVYMSPFYGYREGSHTEHTTYAADRFKQVDGFYARDLTTKARATAPTTRNLLTTPKFTVAWDWVPKRPSVCTMTKWQEVDEMLRSEYGGSFRFSSDAISTTFTTNLTEYPLSRVDLGDCIGKDARDAMDRIFARRYNATHIKVGQPQYYQANGGFLIAYQPLLSNTLAELYVREHLREQSRKPPNPTPPPPGASANASVERIKTTSSIEFARLQFTYNHIQRHVNDMLGRVAIAWCELQNHELTLWNEARKLNPNAIASVTVGRRVSARMLGDVMAVSTCVPVAADNVIVQNSMRISSRPGACYSRPLVSFRYEDQGPLVEGQLGENNELRLTRDAIEPCTVGHRRYFTFGGGYVYFEEYAYSHQLSRADITTVSTFIDLNITMLEDHEFVPLEVYTRHEIKDSGLLDYTEVQRRNQLHDLRFADIDTVIHADANAAMFAGLGAFFEGMGDLGRAVGKVVMGIVGGVVSAVSGVSSFMSNPFGALAVGLLVLAGLAAAFFAFRYVMRLQSNPMKALYPLTTKELKNPTNPDASGEGEEGGDFDEAKLAEAREMIRYMALVSAMERTEHKAKKKGTSALLSAKVTDMVMRKRRNTNYTQVPNKDGDADEDDL
What is the function of this protein?
Envelope glycoprotein that forms spikes at the surface of virion envelope.  Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans.  Involved in fusion of viral and cellular membranes leading to virus entry into the host cell.  Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.  May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress.  Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).
What are the official names of this protein?
Envelope glycoprotein B, gB.
What is the protein family that this protein belongs to?
Belongs to the herpesviridae glycoprotein B family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein. Host endosome membrane; Single-pass type I membrane protein. Host Golgi apparatus membrane; Single-pass type I membrane protein. Note=During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs. It is probably transported to the cell surface from where it is endocytosed and directed to the trans-Golgi network (TGN).
Protein: CTR3_HUMAN
Sequence: MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIALHVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETKTGEEVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEIKSNQPSRKSRAKTVDLDPGTLYVHSV
What is the function of this protein?
Uniporter that mediates the uptake of cationic L-amino acids such as L-arginine, L-lysine and L-ornithine (PubMed:11591158).  The transport is sodium ions- and pH-independent, moderately trans-stimulated and is mediated by passive diffusion (PubMed:11591158).
What are the official names of this protein?
Cationic amino acid transporter 3, CAT-3, CAT3, Cationic amino acid transporter y+, Solute carrier family 7 member 3.
What is the protein family that this protein belongs to?
Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: RBS1_MESCR
Sequence: MASSMVSSAAVATVNRTPAQASMVAPFNGLKSVAAFPVTKKNNDITSVATNGGRVQCMQVWPPLGKKKFETLSYLPPLSEESLMKEVQYLLNNGWVPCLEFEPTHGFVYREHGNTPGYYDGRYWTMWKLPMFGCTDPSQVVAELEEAKKAYPEAFIRIIGFDNVRQVQCISFIAYKPASYDA
What is the function of this protein?
RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate.  Both reactions occur simultaneously and in competition at the same active site.  Although the small subunit is not catalytic it is essential for maximal activity.
What are the official names of this protein?
Ribulose bisphosphate carboxylase small subunit, chloroplastic 1, RuBisCO small subunit 1.
What is the protein family that this protein belongs to?
Belongs to the RuBisCO small chain family.
What are the subcellular locations of this protein?
Plastid, chloroplast.
Protein: ADC_BURPS
Sequence: MKPSQVRSKAFAMPLTSPAFPMGPYRFVNREFLIITYRTDMDRLREIVPEPLEVKEPLVHYEFIRMPDSTGFGDYTESGQVIPVEYKGQPGGYTLAMYLNDHPPIAGGRELWGFPKKLAQPTLQTHIDTLLGTLDYGPVRVATGTMGYKHQELDLEEQAKRLAGANFLLKIIPHVDGSARVCELVRYYLQDIEMKGAWTGPASLQLAPHALAPVADLPVLEIVEARHLLADLTLGLGEVVYDYLAQ
What is the function of this protein?
Catalyzes the conversion of acetoacetate to acetone and carbon dioxide.
What are the official names of this protein?
Acetoacetate decarboxylase, AAD, ADC.
What is the protein family that this protein belongs to?
Belongs to the ADC family.
Protein: MURJ_RHIME
Sequence: MSLVKKFATVGGATLGSRLFGFIRETFMAAALGTGPVADAFNTAFRLPNTFRRLFAEGAFNSAFVPLFAKEIEAHGMDGARRFSEEVFGVLFTVLLLLTIAMELSMPFIVGQLIAPGFADDPAKFTSTVTFATIMFPYLACMSLAAMMAGMLNSLHRYFAAAIAPVFLNFILIAVLAYAWYSGQDAVAVGYDLSWGVLAAGLVQLAIVWVAVRNAGIRIGFRRPRLTPNVKRLLVLALPAAITGGITQINLLINTNIASAKEGAVSSLVYADRIYQLPLGVVGIAVATVLLPELARALRGGNLNEAANLQNRSVEFTLFLTLPAAAALLVMSEPIVRLLFERGQFSPESTVVVGHILAIYGLGLPAFVLIKAFIPGFFAREDTRTPMIFAGISVAVNVSLALTLFPSLAASGIATAEIVAGWVNALLLFATLVWRGHWGRDIPLLTRIPRLVIAAAIMAAALYVAVDWLAFPLSSAAPLSTRALTLCGLIAAAMAIYFAVAFGIGGASLSMIRRSVKRGASASSVERASEGADRQ
What is the function of this protein?
Involved in peptidoglycan biosynthesis.  Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
What are the official names of this protein?
Probable lipid II flippase MurJ.
What is the protein family that this protein belongs to?
Belongs to the MurJ/MviN family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: RL6_ECOL6
Sequence: MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVKHADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNVINLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGKGVRYADEVVRTKEAKKK
What is the function of this protein?
This protein binds to the 23S rRNA, and is important in its secondary structure.  It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
What are the official names of this protein?
50S ribosomal protein L6.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL6 family.
Protein: Y1551_ACTP7
Sequence: MSIQSSEIIETIKMVADQNFDVRTITIGIDLHDCISADIDQLNQNIYQKITTIGKDLVETAKILSAKYGIPIVNQRISVTPIAQIAAATKADSYVSIAQTLDRAAKAIGVSFIGGFSALVQKGMSPSDEVLIRSIPEAMQTTDIVCSSINIGSTRAGINMDAVKLAGETIKRTADITPEGFGCAKIVVFCNAVEDNPFMAGAFHGSGEADAIINVGVSGPGVVKEALENSNATTLTEVAEVVKKTAFKITRVGELIGQEAAKMLNIPFGILDLSLAPTPAVGDSVARILEAMGLSVCGTHGTTAALALLNDAVKKGGMMASSSVGGLSGAFIPVSEDEGMIAAAESGILTLDKLEAMTAVCSVGLDMIAVPGKTPAHTISGIIADEAAIGMINSKTTAVRIIPVTGKDVGESVEFGGLLGYAPIMPVKEGSCEVFVNRGGRIPAPVQSMKN
What are the official names of this protein?
UPF0210 protein APP7_1551.
What is the protein family that this protein belongs to?
Belongs to the UPF0210 family.
Protein: TYSY_HHV8P
Sequence: MFPFVPLSLYVAKKLFRARGFRFCQKPGVLALAPEVDPCSIQHEVTGAETPHEELQYLRQLREILCRGSDRLDRTGIGTLSLFGMQARYSLRDHFPLLTTKRVFWRGVVQELLWFLKGSTDSRELSRTGVKIWDKNGSREFLAGRGLAHRREGDLGPVYGFQWRHFGAAYVDADADYTGQGFDQLSYIVDLIKNNPHDRRIIMCAWNPADLSLMALPPCHLLCQFYVADGELSCQLYQRSGDMGLGVPFNIASYSLLTYMLAHVTGLRPGEFIHTLGDAHIYKTHIEPLRLQLTRTPRPFPRLEILRSVSSMEEFTPDDFRLVDYCPHPTIRMEMAV
What are the official names of this protein?
Thymidylate synthase, TS, TSase.
What is the protein family that this protein belongs to?
Belongs to the thymidylate synthase family.