PharMolix/UniProtQA huggingface dataset:
Protein: APTX_CIOIN
Sequence: MRILYRLLKMADDTVKCYLECCKSSHPKLPLPHNVPVIIGRTPELGITDKLCSRSQLELTSNCYKRYVLVKRLGANTSQINGIDIEKNKSSRLEEGQDLHVVNGKFPHRVYFTGCQNDTKTEKAVVPKLPTKSTDLTKSDLSIKQPERKKLKVSENKSKVLNSKIKPQEKFSSESVYAFDSPSPMSSRCEKKAESNKRAPTHKHWSQGLKASMEDPELVVKEDEQIVVIKDKYPKAKYHWLILPKDSISSTKNLSTDNIELLKHILKVGQELAAEVKDKQPDVEFRFGYHAVASMSQMHMHVISQDFQSSSFKTKKHWNSFTTDYFVDATDIINELETGGKVKDRRTMTSLLNEPLKCHRCKKPQKNIPTLKKHIDSCQK
What is the function of this protein?
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair.  Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species.  Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined.  Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (By similarity).  Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) (By similarity).
What are the official names of this protein?
Aprataxin, Forkhead-associated domain histidine triad-like protein, FHA-HIT.
What are the subcellular locations of this protein?
Nucleus, nucleoplasm. Nucleus, nucleolus.
Protein: HFLD_SALPK
Sequence: MAKNYYDITLALSGICQSARLVQQLAHQGHCDADALHVSLNSVIDMNPSSTLGVFGGSEANLRLGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSAKGALNTLGDRINGLQRQLDHFDLQSDTLMSAMAGIYVDVISPLGPRIQVTGSPAVLQSPQVQAKVRASLLAGIRAAVLWHQVGGGRLQLMFSRHRLTTQAKQILAHLTPEL
What are the official names of this protein?
High frequency lysogenization protein HflD homolog.
What is the protein family that this protein belongs to?
Belongs to the HflD family.
What are the subcellular locations of this protein?
Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: C4BPA_BOVIN
Sequence: MKHQRVPVMILHSKGTMASWPFSRLWSISDPILFQVTLVATLLATVLGSCGIPPYLDFAFPINELNETRFETGTTLRYTCRPGYRISSRKNFLICDGTDNWKYKEFCVKKRCENPGELLNGQVIVKTDYSFGSEIEFSCSEGYVLIGSANSYCQLQDKGVVWSDPLPQCIIAKCEPPPTISNGRHNGGDEDFYTYGSSVTYSCDRDFSMLGKASISCRVENKTIGVWSPSPPSCKKVICVQPVVKDGKITSGFGPIYTYQQSIVYACNKGFRLEGDSLIHCEADNSWNPPPPTCELNGCLGLPHIPHALWERYDHQTQTEQQVYDIGFVLSYKCHFGYKPETDGPTTVTCQSNLEWSPYIECKEVCCPEPNLNNYGSITLHRRPSTSTHCTYISGDKISYECHSKYMFDALCTKHGTWSPRTPECRPDCKSPPVIAHGQHKVVSKFFTFDHQAVYECDKGYILVGAKELSCTSSGWSPAVPQCKALCLKPEIEYGRLSVEKVRYVEPEIITIQCESGYSVVGSENITCSEDRTWYPEVPKCEWEYPEGCEQVVTGRKLLQCLSRPEEVKLALEVYKLSLEIEILQTNKLKKEAFLLREREKNVTCDFNPE
What is the function of this protein?
Controls the classical pathway of complement activation.  It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b.  It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a.  Alpha chain binds C4b.  It interacts also with serum amyloid P component.
What are the official names of this protein?
C4b-binding protein alpha chain, C4bp.
What are the subcellular locations of this protein?
Secreted.
Protein: RL25_HELPY
Sequence: MLEGVIRESITKANAKALKKDGYLIANVYGKGIENVNGAFKLNPFIKYLKEKKHLIFPVKLGDKTFEVVVQEYQKNPVTNELIHVDLLAVTKGVKSKFKVPIKHQGTPVGLKNKGILMLSKKRISVECAPEHLPDHYLVDVAPLDVNESILVRDLEKHENVKILDHDSIAVIGVIKAK
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25, General stress protein CTC.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
Protein: SYC_LIMF3
Sequence: MLKIYNTLTRQKEEFHPQQAGIVNMYVCGPTVYNYIHIGNARSVVAFDTVRRYLEFSGYQVNYVSNFTDVDDKMIKAAKEQGITVPELAYKYIQAYMEDTAALNVEPATTHPRATENIDGIISFIEDLIEKGYAYQSGGDVYYRARKFAHYGQLSGQSLDDLEVGASEHVSTEEVAKKKDPLDFALWKAAKPGEIKWDSPWGAGRPGWHIECSVMSTKYLGDTLDIHAGGQDLEFPHHENEIAQSEAKTGHRFVNYWMHNGFVTIGRDNEKMSKSLGNFVTVHDLIKEVDPQVLRFFMSTTQYRRPIQYSQESLVEAQANLEHLKNTYDNLAYRLKDATSGTDGGVQRQLADFRARFVAAMDDDINVQNGIAVVYELMRFANQYVEQRLVQREPIVAIQLMLKRLVAVFGVDLAVSATEINDEKIKELIEKRNAARAEKDFALSDQIRDQLRDQGIILEDTPQGTRYRKESN
What are the official names of this protein?
Cysteine--tRNA ligase, Cysteinyl-tRNA synthetase, CysRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KEX1_CANAL
Sequence: MKLILSTLIVFIHTLLVSALPTKEGSDPNSAKKYLVSDLPGLHENITPDNSIPLMFAGQLEIYPETDTHYFFWKFSDSNPETVTNRTIFWLNGGPGCSSMDGALLETGPFRINSQQQVISNNGSWHKMGDIIYVDQPAGTGFSYSDTYITDLDQVAEYFLKFMEKYYELFPEEIGYEIYFAGESYAGQYIPYIADAILQRNKKLVDGEHKYDLRGVLIGNGWVSPNEQSLSYLPFFKDHGLIDVHHPKWATLLAKHEQCQKIVNKIDSTFDDGVVHYYEVSSSTCEAILTDLLEYTQDTASEKDQRCVNMYDYTLRDSYPSCGMNWPYELVNVGPFLRQEKVMHQLNLINLKKWNECNGRVGRTFQARHSIPAVHLLPELAKEIPVMLFNGANDIICNSQGVLSYLQKLQWNGETGFTNKDNQISWIYDNKEVGYIIWERNISFINIYNSSHMVPYDLPDVSRALIDLITGKYDEKDVDGKKSFVTYPLGSRKESDASADGEENAGSDKVPGDSPSQTIDPMISSSTASSSSVESSLSSSTASADSDSTSSKFTRLIQLAVILVIFWGVYVLYASYKSRPSSIIKKPTNNTSNVTRSSAGKKKNVQWADQLNQFEDDERTQEPNQGIIAKAIGKITGSKDTRGRYAPVQRGNGNEYIDDIELGEGLSDPNVDEFIIGSDDDEEQGQAHSGAATHNQKQKPMN
What is the function of this protein?
Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors.  Promotes cell fusion and is involved in the programmed cell death (By similarity).
What are the official names of this protein?
Pheromone-processing carboxypeptidase KEX1, Carboxypeptidase D.
What is the protein family that this protein belongs to?
Belongs to the peptidase S10 family.
What are the subcellular locations of this protein?
Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein.
Protein: 3NBB_COERA
Sequence: QAIGPPYGLCFQCNQKTSSDCTEARRCSPFHEKCYTLYQPDENWMKSSGLSHFGCGKQCPTAGPEGRVTCCLTPRCN
What is the function of this protein?
Potent postsynaptic neurotoxin.  Displays readily reversible competitive antagonism at the nicotinic acetylcholine receptor (nAChR).
What are the official names of this protein?
Alpha-colubritoxin.
What is the protein family that this protein belongs to?
Belongs to the snake three-finger toxin family. Ancestral subfamily. Boigatoxin sub-subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: MRGB2_MOUSE
Sequence: MSGDFLIKNLSTSAWKTNITVLNGSYYIDTSVCVTRNQAMILLSIIISLVGMGLNAIVLWFLGIRMHTNAFTVYILNLAMADFLYLCSQFVICLLIAFYIFYSIDINIPLVLYVVPIFAYLSGLSILSTISIERCLSVIWPIWYRCKRPRHTSAITCFVLWVMSLLLGLLEGKACGLLFNSFDSYWCETFDVITNIWSVVFFGVLCGSSLTLLVRIFCGSQRIPMTRLYVTITLTVLVFLIFGLPFGIYWILYQWISNFYYVEICNFYLEILFLSCVNSCMNPIIYFLVGSIRHRRFRRKTLKLLLQRAMQDTPEEEQSGNKSSSEHPEELETVQSCS
What is the function of this protein?
Mast cell-specific receptor for basic secretagogues, i. e.  cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core.  Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium.  In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction (PubMed:25517090).
What are the official names of this protein?
Mas-related G-protein coupled receptor member B2.
What is the protein family that this protein belongs to?
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: Y2616_CLOBK
Sequence: MSRLSKEEISERLLELIKDETKPAIGCTEPVAVAFTVATGKKYMQGEILKIDLKVSKNILKNGKSVTIPNTEVCGLDIAGALGGICGDPEEGLFVFKNVNKDYLDKAREMIKNKVVTLNPIENTDPVFVEATLKGEKDEVIVILRRGHTNIEKVIVNGEIAFEKDNKNEKDNKDCDFMKELSLKDIREITEDISIEKLGFIMDGIEMNKEAAKEGLKRQKGLTLGSSLLKLQQEGKLGKDSATIARILTAAGSDLRMGGGMCPIMTSGGSGNQGLCVILPITVVAEDIKAPKEKLQRAVFFGHAVNNFVKKYTGKLSAICGCAIAAGIGATAGITWLLGGKDKEINGAILNMLANLTGMVCDGAKGSCAIKLSTSASEAVISAYLALNDIIVPNNTGIIGNTVEDTINNLGMLCKDGFYKADDVMLSIACKEVI
What are the official names of this protein?
UPF0597 protein CLD_2616.
What is the protein family that this protein belongs to?
Belongs to the UPF0597 family.
Protein: NU6M_BOVIN
Sequence: MMLYIVFILSVIFVMGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLNFGGSFLGLMVFLIYLGGMMVVFGYTTAMATEQYPEIWLSNKAVLGAFVTGLLMEFFMVYYVLKDKEVEVVFEFNGLGDWVIYDTGDSGFFSEEAMGIAALYSYGTWLVIVTGWSLLIGVVVIMEITRGN
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.  Essential for the catalytic activity and assembly of complex I.
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 6, NADH dehydrogenase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 6 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: Y921_BRUSU
Sequence: MKRGCAIAVMICGLITSVSAASAADLIVQEPVFEPLPQPALAGWYLRGDIGYNFKSKTGGKWNFWNQFEEPYRGVDDTFNYDDFSLKGGASYGVGVGYRFNDMLRTDLTLDYFRASINGRTNCPSYVKSSHGLNPVEDNCHYEDNSKASVWTAMANAYVDLPRVGPLTPYLGAGIGAAYVKYDTWKTSEICPTCTLQSDKDGFDSWRFAMALMAGVSYDLTDQLKLDLGYRYLRVNGGNAYGYDEQDRQVINQYGQGAGADGPQAKDNGFNIHTVRAGLRYEFR
What are the official names of this protein?
Uncharacterized protein BRA0921/BS1330_II0913.
What is the protein family that this protein belongs to?
Belongs to the surface antigen msp4 family.
Protein: CU03_HOMAM
Sequence: DRDAQTLTDERNDQGDGNFRYEFETSNGIYTQKTGTPGSEGQSNYQGSFRFPLEDGTIAEVTYIADEYGFQPSSDLLPVGPPAPPHVQRLLEIAEDQRRQGITFD
What are the official names of this protein?
Cuticle protein AMP3, HA-AMP3.
Protein: METK_CHLTE
Sequence: MSHSRYYFTSESVSEGHPDKVADQISDAVLDEFIKQDPNSRVACETFVTTGQVIVGGEVTSKGIVDVQTIARKTITEIGYTKGEYMFDANSCGILSALHSQSPDINRGVDRKEEIADEFDRVGAGDQGMMFGYACTETPELMPAAIQYAQELVRLLAEIRKEGKIMTYLRPDAKSQVTLEYDGNDNVLRVEAVVVSTQHDPEPAGMSEAEFQAVIKNDVIENVIKKVIPAKLIDENTKFHINPTGRFEIGGPHGDTGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAARHVAKNIVAAGLADKCTVQVSYAIGVARPISIYINTHGTSKHGLSDEQIQEKAEAIFDLRPLAIIRRFNLDRPHGWCYRDTAAYGHFGREQFPWEKTEKVAELKAALGL
What is the function of this protein?
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP.  The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
What are the official names of this protein?
S-adenosylmethionine synthase, AdoMet synthase, MAT, Methionine adenosyltransferase.
What is the protein family that this protein belongs to?
Belongs to the AdoMet synthase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YPFN_SHISS
Sequence: MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPPHRDFNDKWDDDDDWPKKDQPKK
What are the official names of this protein?
UPF0370 protein YpfN.
What is the protein family that this protein belongs to?
Belongs to the UPF0370 family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: YEXN_AERSA
Sequence: DPFMQALEQGLPAGVWTLAQVSQGRLDPEYRHHFYQATGWQEEVGLILPVRDGLTLMLFLGRLDKRSTLSRDELARLEGVFPLVHSLCRQQWQQSQPLLAQSTAQPDSTSLKSAVEQAMASVGGDRLTRRERQVAELLLQGLDTEAIAAALGIGNGTVKNHRKHLYGKLRLGSRAELFNLFLNHLITAPVGDIQTP
What are the official names of this protein?
Putative HTH-type transcriptional regulator in exeN 3'region, ORF2.
Protein: YEGS_SALA4
Sequence: MANFPASLLILNGKSADNQPLREAITLLRDEGIQIHVRVTWEKGDAQRYVDEARRLGVETVIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPEALDKALKLAIAGNAMEIDMARVNDKTCFINMATGGFGTRITTETPEKLKAALGGVSYLIHGLMRMDTLTPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPTALINDGLLQLRIFTGEELLPALFSTLTQSDDNPNIIDGASAWFDIHAPHEITFNLDGEPLSGQEFHIEVLPGALRCRLPPDCPLLR
What is the function of this protein?
Probably phosphorylates lipids; the in vivo substrate is unknown.
What are the official names of this protein?
Probable lipid kinase YegS.
What is the protein family that this protein belongs to?
Belongs to the diacylglycerol/lipid kinase family. YegS lipid kinase subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MTURN_HUMAN
Sequence: MDFQQLADVAEKWCSNTPFELIATEETERRMDFYADPGVSFYVLCPDNGCGDNFHVWSESEDCLPFLQLAQDYISSCGKKTLHEVLEKVFKSFRPLLGLPDADDDAFEEYSADVEEEEPEADHPQMGVSQQ
What is the function of this protein?
Promotes megakaryocyte differentiation by enhancing ERK and JNK signaling as well as up-regulating RUNX1 and FLI1 expression (PubMed:24681962).  Represses NF-kappa-B transcriptional activity by inhibiting phosphorylation of RELA at 'Ser-536' (PubMed:24681962).  May be involved in early neuronal development (By similarity).
What are the official names of this protein?
Maturin, Maturin neural progenitor differentiation regulator protein homolog, Protein Ells1.
What is the protein family that this protein belongs to?
Belongs to the MTURN family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: VSP13_TRIST
Sequence: MVLIRVLANLLILQLSYAQRSSELVIGGDECNINEHRFLVALYKSGRFRCGGTLINQEWVLTAAHCDRRNMEIKLGMHSKNVPNEDEQRRVPKEKFFCDSNKNHTQWNKDIMLIRLNSPVNNSTHIAPLSLPSNPPIVGSVCRIMGWGTITSPNETYPDVPHCANINLFNYTVCHGAHAGLPATSRTLCAGVLEEGKDTCKGDSGGPLICNGQFQGIVSWGGDPCAQPREPGVYTKVFDHLDWIQNIIAGNTTATCPL
What is the function of this protein?
Snake venom serine protease that may act in the hemostasis system of the prey.
What are the official names of this protein?
Snake venom serine protease KN13, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PNCB_RHIEC
Sequence: MAKTDIARRVYNHAWKLDPIIRSLIDTDFYKLLMLQMIWKLYPDVNASFTLINRTKRVHLAEEIDEGDLREQLDHARTLRLSKKEMIWLAGNSFYGRAQIFEPEFLAWLSNFQLPEYELSKKDGQYVLDFHGSWKETTMWEIPALAIVNELRSRSAMKALGPFTLDVLYARAKAKMWSKVERLKELPGLRISDFGTRRRHSFLWQRWCVEALKEGIGPAFTGTSNVLLAMDSDLEAVGTNAHELPMVAAALAQTDEQLRNAPYKILRDWNKLYGGNLLIVLPDAFGTAAFLRDAPEWVADWTGFRPDSAPPIEGGEKIIDWWKKMGRDPRQKLLIFSDGLDVDAIIDTYRHFEGRVRMSFGWGTNLTNDFAGCAPTEISGLNPISIVCKVSDANGRPAVKLSDNPQKATGEPAEVERYLKFFGAEDRVDQTVLV
What is the function of this protein?
Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
What are the official names of this protein?
Nicotinate phosphoribosyltransferase, NAPRTase.
What is the protein family that this protein belongs to?
Belongs to the NAPRTase family.
Protein: IF6_TOXGV
Sequence: MNASCAALWSLGSSRMATRAQFESSNEVGVFAKLTNSYCLVALGGSEHFYSTLEAELAPHIPVVHATVGGTRVIGRVCVGNRRGLIVPSITTDQELQHLRNSLPDSVEIRRVEERLSALGNNVACNDYVALLHTDMDKETEEIVQDVLGVEAFRATIGKQTLVGSYCHFTNQGGLVHVMTPVEDMEELSQLLQVPLTAGTVNRGSDLVGAGLIANDWAAFCGMDTTATELAVVERIFKIATRNQQKLNLVDDLTLRSSLIDTLS
What is the function of this protein?
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm.  May also be involved in ribosome biogenesis.
What are the official names of this protein?
Eukaryotic translation initiation factor 6, eIF-6.
What is the protein family that this protein belongs to?
Belongs to the eIF-6 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus, nucleolus. Note=Shuttles between cytoplasm and nucleus/nucleolus.
Protein: Y1638_METJA
Sequence: MNFEKIIEEKVNQKLKELRLKNSLEILEKLDINTELKEALKSTLLKRLNGEKEFYKISIDKKPKAVVAFSGGVDSSTSAIIAKQIFDVKAVSCYSKYIMTDEMRENAKNIAKKIGISLEFVSIDLEEVYKGVVNGKFHPCGRCHKVIENAVIDYAKKIDAEFVIFGDLLAFGYLALYREDEIFRFNLPSFFALTKDEEREILKNNGIELKMSYGCPLLKIYHKHNKGYKFTIQRILREVRGRVVNEEEGFKNIVEILNQQ
What are the official names of this protein?
Uncharacterized protein MJ1638.
Protein: DXS_RENSM
Sequence: MGLLETIQHPADLARLSDEQLVQLAQEIRDFLISNVAQTGGHLGPNLCVVELTLAIHRVFDSPRDSIIFDTGHQSYVHKLVTGRQHFSTLRQQGGLSGYADRGESVHDVVESSHASSSLSWADGISRARVLNGEGDRYVVAVIGDGALTGGMTWEALNNIAADKDRRVVIVVNDNGRSYAPTVGGLADYLRSLRPAIDSLRTHKAYEGNLDWTKNKLQNGGFLGQLMYKSLHAAKKGVKDWWAPQGLFEDLGMKYIGPVDGHDQKALESAMQTAKNYAGPVIVHAMTDKGRGYAPARADEADQFHAVGVIDPETGLPLDPSTAQSWTSVFAEEIAEIADERDDIVGITAAMLIPVGLHRMAERHPQRVIDVGIAEQHALTTAAGMAFGGLHPVVAMYATFLNRGFDQLLMDVALHKAGVTVVLDRAGVTGPDGPSHHGMWDLSMLQIIPGLHLAAPRDATRLREELREAVAISDAPTVLRYSKGNVGAEVEAIERLDDGVDILARRPAGSTENDVLLVSVGAMSEMSLQVANLLGAQGISSTVVDPRWVLPVPQSIIELAAQHRIVIVIEDGVRAGGVGSRIRQEMRAAGVDTALNEVGLPVEFLAHGSRGQVLDRVGLTAQKVAHDVVAQVLGTKVPFARPLPNEQITHTGQFPTL
What is the function of this protein?
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
What are the official names of this protein?
1-deoxy-D-xylulose-5-phosphate synthase, 1-deoxyxylulose-5-phosphate synthase, DXP synthase, DXPS.
What is the protein family that this protein belongs to?
Belongs to the transketolase family. DXPS subfamily.
Protein: SYM_MANSM
Sequence: MSNQHRQILVTCALPYANGPIHLGHMLEHIQADIWVRFQRMRGNEIHFVCADDAHGTPIMLKADQMGITPEQLIADVKEKHYADFCGFNISFDNYHSTHSEENRELSELIYSRLKENGFIKSRTISQLFDPEKSMFLPDRFVKGTCPKCKAEDQYGDNCEVCSATYSPTELINPRSAVSGATPVIKESEHFFFDLPSFESMLKEWNRSGALQSEVANKMQEWFDAGLQQWDISRDAPYFGFKIPGTENKYFYVWLDAPIGYMASFKNLCKRENLDFDRFWNKDSNTELYHFIGKDIMYFHSLFWPAMLDGANYRKPTNIFVHGYVTVNGEKMSKSRGTFIQAATYLKHLDPECLRYYYAAKLSNRIDDLDLNLDDFVQRVNTDLVNKLVNLASRNAGFIQKRFDGKLADKLEDESLFAEFIAQSEQIAAYYENREFGKAIREIMALTDKANKYVDDKAPWVIAKEEGREAELQAVCSMGIQLFRVLMGYLKPVLPKLAERSEAFLQAELTWDNLAQPLLNHGIAPFKALFSRLDVKQIDAMIEASKAENAAVNATVKKEEKNSKKSTALLTDFEPIEPEISIDDFAKIDLRVAKVIKCEEVPESKKLLKFQLDLGFEQRQVLSGIKGAYNNPEELEGRFVIVVANLAPRKMKFGVSEGMILSAGTGGEDLYLLDVDAGVKAGSRVM
What is the function of this protein?
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
What are the official names of this protein?
Methionine--tRNA ligase, Methionyl-tRNA synthetase, MetRS.
What is the protein family that this protein belongs to?
Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PTR7_ARATH
Sequence: MSLPETKSDDILLDAWDFQGRPADRSKTGGWASAAMILCIEAVERLTTLGIGVNLVTYLTGTMHLGNATAANTVTNFLGTSFMLCLLGGFIADTFLGRYLTIAIFAAIQATGVSILTLSTIIPGLRPPRCNPTTSSHCEQASGIQLTVLYLALYLTALGTGGVKASVSGFGSDQFDETEPKERSKMTYFFNRFFFCINVGSLLAVTVLVYVQDDVGRKWGYGICAFAIVLALSVFLAGTNRYRFKKLIGSPMTQVAAVIVAAWRNRKLELPADPSYLYDVDDIIAAEGSMKGKQKLPHTEQFRSLDKAAIRDQEAGVTSNVFNKWTLSTLTDVEEVKQIVRMLPIWATCILFWTVHAQLTTLSVAQSETLDRSIGSFEIPPASMAVFYVGGLLLTTAVYDRVAIRLCKKLFNYPHGLRPLQRIGLGLFFGSMAMAVAALVELKRLRTAHAHGPTVKTLPLGFYLLIPQYLIVGIGEALIYTGQLDFFLRECPKGMKGMSTGLLLSTLALGFFFSSVLVTIVEKFTGKAHPWIADDLNKGRLYNFYWLVAVLVALNFLIFLVFSKWYVYKEKRLAEVGIELDDEPSIPMGH
What is the function of this protein?
Dual affinity nitrate transporter.  Involved in proton-dependent nitrate uptake and in the regulation of the nitrate transporter NRT2. 1.  Acts also as a nitrate sensor that trigger a specific signaling pathway stimulating lateral root growth and seed germination.  The uptake activity is not required for sensor function.  Displays an auxin transport facilitation inhibited by high nitrate concentration.  Required to prevent auxin accumulation in preemerged lateral root primordia and young lateral roots when external nitrate concentration is low or null.  May be involved in the basipetal transport of auxin out of the lateral root tips.  Acts as a bidirectional transporter involved in root-to-shoot nitrate translocation.  Recognizes specifically nitrate and chlorate, but not nitrite, alanine, sulfate, phosphate or the di-peptide Ala-Ala.
What are the official names of this protein?
Protein NRT1/ PTR FAMILY 6.3, AtNPF6.3, Nitrate transporter 1.1, AtNRT1, Nitrate/chlorate transporter, Protein CHLORINA 1.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
What are the subcellular locations of this protein?
Membrane; Multi- pass membrane protein.
Protein: ARF3_MOUSE
Sequence: MGNIFGNLLKSLIGKKEMRILMVGLDAAGKTTILYKLKLGEIVTTIPTIGFNVETVEYKNISFTVWDVGGQDKIRPLWRHYFQNTQGLIFVVDSNDRERVNEAREELMRMLAEDELRDAVLLVFANKQDLPNAMNAAEITDKLGLHSLRHRNWYIQATCATSGDGLYEGLDWLANQLKNKK
What is the function of this protein?
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.  Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
What are the official names of this protein?
ADP-ribosylation factor 3.
What is the protein family that this protein belongs to?
Belongs to the small GTPase superfamily. Arf family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasm, perinuclear region.
Protein: NKPD1_HUMAN
Sequence: MQQEAAQRESEELQHVQWRPRAVSGWGVPQLLWYLVFLQPIITEVHLRRRNVQFLFIRFSAWQYAGTDKLWAGLVTTLCEGIRRHYGALPFSVYSVLGNKPATRQDCCQSEWHCRRRVCLGLLALLAALGLGVGLLYLSLGGHALGHGSPSGSLLKVFGGAATTLSGSGLLMAVYSVGKHLFVSQRKKIERLVSREKFGSQLGFMCEVKKEVELLTDFLCFLEIYQRRRLRVVLEVTGLDTCYPERVVGVLNAINTLLSDSHAPFIFILVVDPSILAACLESAGNMKGTADNGYLFLNRTVTLPFSVPIMGRRTKLQFLHDAVQSRDDLLYREMTRKPWLPGDAGGESAQLLAVQAQAGTERGQGRIDDEAARRIQEALFCLHDERDCLYEYVPDNVVSMRRIVNTVPITVRLLQQQQQQGDFGGPTPRQAVAWVVLANQWPCRLSWALQCLEDRQQTGGAPEGRARLWDVFRDNSRELHTMTKALQNVLDLDGDPELFERFLGADFPFTVAEAQSLLRCTVNLDHSIRRRMGLIRAVSALKPPSPPKSPTRDTPHAAHRANSASRAPPSGRASGQAGEGHHTGDLAHRGKLWPVACALFRPGQSSPGGP
What are the official names of this protein?
NTPase KAP family P-loop domain-containing protein 1.
What are the subcellular locations of this protein?
Membrane; Multi-pass membrane protein.
Protein: STC_ANGAU
Sequence: MLRMSGLILTLVLVTAAYEQDESEPLSPRTARFSASSPSDVARCLNGALQVGCSAFACLDNSTCNTDGMHEICRSFLHGAAKFDTQGKTFVKESLKCIANGITSKVFLTIRRCSSFQKMISEVQEECYSKLDLCSVAQSNPEAMGEVAQVPSQFPNRYYSTLLQSLLTCDEDTVEQVRAGLVSRLEPEMGVLFQLLQTKACPPSAAGGTGPVGAGGSWRWPMGPPMFKIQPNLRSRDPTHLFAKKRSTSS
What is the function of this protein?
Its primary function is the prevention of hypercalcemia.  Upon release into the circulation, it lowers calcium transport by the gills, thereby reducing its rate of influx from the environment into the extracellular compartment.  STC also stimulates phosphate reabsorption by renal proximal tubules.  The consequence of this action is increased levels of plasma phosphate, which combines with excess calcium and promotes its disposal into bone and scales.
What are the official names of this protein?
Stanniocalcin, STC, Corpuscles of Stannius protein, CS, Hypocalcin, Teleocalcin.
What is the protein family that this protein belongs to?
Belongs to the stanniocalcin family.
Protein: PA2B1_LATCO
Sequence: MYPAHLLVLLAVCVSLLGASAISNRPRNLVQFSELIQCVNKGKRATYHYMDYGCYCGKGGSGTPVDALDRCCKTHDDCYGQAEKKGCFPLLSLYNFACFPGAPQCGKGNTCQRFVCACDLKAALCFAKSPYNNNNYNIDIKKKCQTLIYMRLQTQ
What is the function of this protein?
Snake venom phospholipase A2 (PLA2) that inhibits neuromuscular transmission by blocking acetylcholine release from the nerve termini.  PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity).
What are the official names of this protein?
Basic phospholipase A2 PC1, svPLA2, Phosphatidylcholine 2-acylhydrolase.
What is the protein family that this protein belongs to?
Belongs to the phospholipase A2 family. Group I subfamily. D49 sub-subfamily.
What are the subcellular locations of this protein?
Secreted.