PharMolix/UniProtQA huggingface dataset:
Protein: RS13_LEGPC
Sequence: MARIAGVNIPDHKHVVIALTAIYGIGKTTSLKLCKTVDIDPSVKVSQLSDAQLESLRTEIAKITVEGDLRRVVTMNIKRLMDLGCYRGLRHRRGLPLRGQRTKTNARTRKGRRKGTSS
What is the function of this protein?
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA.  In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.  Contacts the tRNAs in the A and P-sites.
What are the official names of this protein?
30S ribosomal protein S13.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS13 family.
Protein: ENO_BIFAA
Sequence: MAVIESVYARQILDSRGNPTVEVVLDTDDGAQGLGLVPSGASTGEAEAWERRDGDKSVYQGKGVLNAVKAVNEEIAPKVIGMDASDQRALDETMIELDGTPNKGRLGANAILGVSLAALYASAESADQPLYRYIGGTNGHILPVPNMNIMNGGAHADFATDIQEYMISPYGFNTYSEALQAGVEVYHTLKNVLKKQGLNTGLGDEGGFAPKMKSNKDSLNYIMDAISAAGYEPGKQIGISLDVASSEFYNKETGKYHFEGDDREAGYMLDFYENLINEYPIVSIEDPFQEEGWDDWAAITAKLGDRLQFVGDDLLVTNPARLAKGIKLGAANSLLVKLNQIGTVTETLDAIELATKNGFTSMVSHRSGETPDTTISDLAVAKNTGQIKTGAPARGERIAKYNRLLEIEEELGSTAQYAGYSAFKACKKYIAE
What is the function of this protein?
Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate.  It is essential for the degradation of carbohydrates via glycolysis.
What are the official names of this protein?
Enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase.
What is the protein family that this protein belongs to?
Belongs to the enolase family.
What are the subcellular locations of this protein?
Cytoplasm. Secreted. Cell surface. Note=Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.
Protein: HMUV_SHIDY
Sequence: MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLLRQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHPHRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLFLDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCVLHDLNLAARYADRIVLMQKGKVIANGKPQDVLTQQELTMLYGADITVLEDPANHSPLIVLDH
What is the function of this protein?
Part of the ABC transporter complex HmuTUV involved in hemin import.  Responsible for energy coupling to the transport system (Probable).
What are the official names of this protein?
Hemin import ATP-binding protein HmuV.
What is the protein family that this protein belongs to?
Belongs to the ABC transporter superfamily. Heme (hemin) importer (TC 3.A.1.14.5) family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein.
Protein: CNBP1_MOUSE
Sequence: MNREGAPGKSPEEMYIQQKVRVLLMLRKMGSNLTASEEEFLRTYAGVVSSQLSQLPQHSIDQGAEDVVMAFSRSETEDRRQ
What is the function of this protein?
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.
What are the official names of this protein?
Beta-catenin-interacting protein 1, Inhibitor of beta-catenin and Tcf-4.
What is the protein family that this protein belongs to?
Belongs to the CTNNBIP1 family.
What are the subcellular locations of this protein?
Cytoplasm. Nucleus.
Protein: SYFA_SHEPC
Sequence: MQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSLSPEEKPAFGQAVNDAKQAIQQKLTERIDGLKSSELEAKLIAEKIDVTLPGRTQENGGLHPVTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEHHPARADHDTFYFNPKLMLRTQTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDEHVNFAELKGILHDFLRNFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL36_KORVE
Sequence: MKVRASVKKICDKCKVIRRHGVVRVICENAKHKQRQG
What are the official names of this protein?
50S ribosomal protein L36.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL36 family.
Protein: GORS1_RAT
Sequence: MGLGASSEQPAGGEGFHLHGVQENSPAQQAGLEPYFDFIITIGHSRLNKENDTLKALLKANVEKPVKLEVFNMKTMRVREVEVVPSNMWGGQGLLGASVRFCSFRRASEHVWHVLDVEPSSPAALAGLRPYTDYIVGSDQILQESEDFFTLIESHEGKPLKLMVYNSESDSCREVTVTPNAAWGGEGSLGCGIGYGYLHRIPTQPSSQYKKPPSASSPGTPAKTPQPNAFPLGAPPPWPIPQDSSGPELGSRQSDYMEALPQVPGGFMEEQLPGPGSPGHGTADYGGCLHSMEIPLQPPPPVQRVMDPGFLDVSGMSLLDSNNTSVCPSLSSSSLLTPTAVSALGPEDIGSSSSSHERGGEATWSGSEFEISFPDSPGSQAQVDHLPRLTLPDGLTSAASPEEGLSAELLEAQTEEPAHTASLDCMAQTEGPAGQVQAAPDPEPGLCEGPW
What is the function of this protein?
Key structural protein of the Golgi apparatus (By similarity).  The membrane cisternae of the Golgi apparatus adhere to each other to form stacks, which are aligned side by side to form the Golgi ribbon (By similarity).  Acting in concert with GORASP2/GRASP55, is required for the formation and maintenance of the Golgi ribbon, and may be dispensable for the formation of stacks (By similarity).  However, other studies suggest that GORASP1 plays an important role in assembly and membrane stacking of the cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis (PubMed:12839990, PubMed:23940043, PubMed:9346242).  Caspase-mediated cleavage of GORASP1 is required for fragmentation of the Golgi during apoptosis (PubMed:11815631, PubMed:12015985).  Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes (By similarity).  Mediates ER stress-induced unconventional (ER/Golgi-independent) trafficking of core-glycosylated CFTR to cell membrane (By similarity).
What are the official names of this protein?
Golgi reassembly-stacking protein 1, Golgi peripheral membrane protein p65, Golgi reassembly-stacking protein of 65 kDa, GRASP65.
What is the protein family that this protein belongs to?
Belongs to the GORASP family.
Protein: RL28_NEIG1
Sequence: MARVCKVTGKRPMSGNNVSHANNKTKRRFLPNLQSRRFWVESENRWVRLRVSNAALRTIDKVGIDVVLADLRARGEA
What are the official names of this protein?
50S ribosomal protein L28.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL28 family.
Protein: DBF4A_HUMAN
Sequence: MNSGAMRIHSKGHFQGGIQVKNEKNRPSLKSLKTDNRPEKSKCKPLWGKVFYLDLPSVTISEKLQKDIKDLGGRVEEFLSKDISYLISNKKEAKFAQTLGRISPVPSPESAYTAETTSPHPSHDGSSFKSPDTVCLSRGKLLVEKAIKDHDFIPSNSILSNALSWGVKILHIDDIRYYIEQKKKELYLLKKSSTSVRDGGKRVGSGAQKTRTGRLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDVDKPSSMQKQTQVKLRIQTDGDKYGGTSIQLQLKEKKKKGYCECCLQKYEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYEKDTPKKKRIKYSVGSLSPVSASVLKKTEQKEKVELQHISQKDCQEDDTTVKEQNFLYKETQETEKKLLFISEPIPHPSNELRGLNEKMSNKCSMLSTAEDDIRQNFTQLPLHKNKQECILDISEHTLSENDLEELRVDHYKCNIQASVHVSDFSTDNSGSQPKQKSDTVLFPAKDLKEKDLHSIFTHDSGLITINSSQEHLTVQAKAPFHTPPEEPNECDFKNMDSLPSGKIHRKVKIILGRNRKENLEPNAEFDKRTEFITQEENRICSSPVQSLLDLFQTSEEKSEFLGFTSYTEKSGICNVLDIWEEENSDNLLTAFFSSPSTSTFTGF
What is the function of this protein?
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation.  Required for progression of S phase.  The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
What are the official names of this protein?
Protein DBF4 homolog A, Activator of S phase kinase, Chiffon homolog A, DBF4-type zinc finger-containing protein 1.
Protein: SSPH_HALH5
Sequence: MLNTQRAQEIAASPIMANVTYQEVPIYIQHVDEQNETARIYPLDNPELEQDVPLSQLMEH
What are the official names of this protein?
Small, acid-soluble spore protein H, SASP H.
What is the protein family that this protein belongs to?
Belongs to the SspH family.
Protein: GCST_ECO7I
Sequence: MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEAQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.
What are the official names of this protein?
Aminomethyltransferase, Glycine cleavage system T protein.
What is the protein family that this protein belongs to?
Belongs to the GcvT family.
Protein: ACCD_CLOP1
Sequence: MIKNLLNKRKYITVSSVELNDTELNEDEKPNIPSGMWSKCEKCAKILYTEDLRENFNVCPNCGHHFKLGAYERIKYLTDENTFVEFDKKMVGRNPLDFNGYEEKIKGYQKKSHVIEGVVTGEAYIAQRKVVLCVMDSNFMMGSMGTAVGEKITRAIEYATKNRLPLIIFTCSGGARMQEGIYSLMQMAKVSGAIYRHGRENLLYITVLTNPTTGGVTASFAMEGDIILSEPGCLVGFAGRRVIEGTINEKLPDDFQTAEFLLEKGFIDKIVQRKDLKQVITSLLRMHEVDYE
What is the function of this protein?
Component of the acetyl coenzyme A carboxylase (ACC) complex.  Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
What are the official names of this protein?
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, ACCase subunit beta, Acetyl-CoA carboxylase carboxyltransferase subunit beta.
What is the protein family that this protein belongs to?
Belongs to the AccD/PCCB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SAV_BPLSK
Sequence: MNYGTNNHYANEYGMELNEYFKHHFNYEELAGWYTMQVLKYLVRAGKKEGESYDKDRNKALDYAGELANLSNENELTEYTTDDIMGFAQDIADDFKQWKDERNNFKSEFTKEEIKAIDERYLEFIEEV
What is the function of this protein?
Involved in the sensitivity of the virus to the host AbiV system.
What are the official names of this protein?
SaV protein, Gene product 26, Gp26.
What is the protein family that this protein belongs to?
Belongs to the skunalikevirus SaV protein family.
Protein: DADA_ECODH
Sequence: MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANAGQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYMENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDAGVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKFRFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYSLTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMVVRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQLLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS
What is the function of this protein?
Oxidative deamination of D-amino acids.
What are the official names of this protein?
D-amino acid dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the DadA oxidoreductase family.
Protein: DDRC_DEIRA
Sequence: MKNAPLTLNFGSVRLPVSADGLLHAPTAQQQLGLTQSWEAALVEHGLPETYRDFGAGPEAAVSVPDFVALAFALDTPEARRWQKRARELLARAMQGDVRVAAQIAERNPEPDARRWLAARLESTGARRELLATVARHGGEGRVYGQLGSISNRTVLGKDSASVRQERGVKATRDGLTSAELLRLAYIDTVTARAIQESEARGNAAILTLHEQVARSERQSWERAGQVQRVG
What is the function of this protein?
Appears to contribute to D. radiodurans capacity to survive exposure to ionizing radiation (PubMed:15454524).  Likely functions as a DNA damage-induced nucleoid-associated protein (NAP) that contributes to the enhanced level of nucleoid compaction after irradiation by bridging DNA duplexes, thereby limiting the dispersion of the fragmented genome immediately after irradiation to facilitate subsequent DNA repair.  In vitro, binds both ssDNA and dsDNA, and is able to compact circular DNA, circularize linear DNA, anneal complementary DNA strands and protect DNA from nucleases (PubMed:35801857, PubMed:28542368).
What are the official names of this protein?
DNA damage response protein C.
Protein: NOMT_ORYSJ
Sequence: MVSPVVHRHAAGGGSGGDDDDQACMYALELLGGSVVSMTLKAAIELGLVDELLAAAGAAVTAEELAARLRLPAAVAAAAAVDRMLRLLASYGVVRCATEAGPDGKARRSYAAAPVCKWLAAGSSSGEGSMAPLGLLNLDKVFMENWYYLKEAVSEGGTAFDKAYGTSLFQYLGQDGNEPSNTLFNQAMASHSVVITNKLLQFFRGFDAGAGVDVLVDVGGGVGATLRMITARHPHLRGVNYDLPHVIAQAPPVEGVEHIGGSMFDHVPSGSAILLKWILHLWGDEECVKILKNCYKALPAKGKVILVEYVLPASPEATLAAQEAFRLDVMMLNRLAGGKERTQQEFTDLAVDAGFSGDCKPTYIFTNVWALEFTK
What is the function of this protein?
S-adenosyl-L-methionine-dependent methyltransferase involved in the biosynthesis of the sakuranetin, an inducible defense mechanism of O. sativa against pathogen attack.
What are the official names of this protein?
Naringenin 7-O-methyltransferase, NOMT, OsNOMT.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family. COMT subfamily.
Protein: RSMJ_MANSM
Sequence: MNIQLICETENSQNFTALCKEKGLTHDPASVLALVQTETDGEVRLELRKLDEPKLGAVYVDFVAGTMAHRRKFGGGRGEAIAKAVGVKGNELPSVIDATAGLGRDAFVLASIGCRVRLVERHPVVYLLLQDGLRRAYADPEIGEMMQKNMQLLPVHHITELNPFEDFADVVYLDPMYPHKQKSALVKKEMRVFQYLVGADSDSNLLLEPALKLAKKRVVVKRPDYAEFLAEKAPQFSRETKNHRFDIYSVNV
What is the function of this protein?
Specifically methylates the guanosine in position 1516 of 16S rRNA.
What are the official names of this protein?
Ribosomal RNA small subunit methyltransferase J, 16S rRNA m2G1516 methyltransferase, rRNA (guanine-N(2)-)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the methyltransferase superfamily. RsmJ family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL25_ACIAD
Sequence: MANFVLNATARNEDKQGKGASRRLRREALVPAIIYGGEAEPVAVTIELRELVKALENNAFFEEVVEVKVGDKVENVKIQALQRHPAKNTPMHADFKRA
What is the function of this protein?
This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L25.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL25 family.
Protein: RECA_STAAU
Sequence: MDNDRQKALDTVIKNMEKSFGKGAVMKLGDNIGRRVSTTSTGSVTLDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQSNGGVAAFIDAEHALDPEYAQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGDTHVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGQEIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDLGVENDIVDKSGAWYSYNGERMGQGKENVKMYLKENPQIKEEIDRKLREKLGISDGDVEETEDAPKSLFDEE
What is the function of this protein?
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs.  It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
What are the official names of this protein?
Protein RecA, Recombinase A.
What is the protein family that this protein belongs to?
Belongs to the RecA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: YTZA_BACSU
Sequence: MRFLFLLFIVFPAIEIGIFLFLGNLIGILPTVLFMILTGIIGAAAAKKQGTEVYYKVQRDLQYGKMPGEAIADGLCIFIGGLLLMLPGFLSDLAGACLLIPFTRGWCKPILFKWLRGMSKNKRIIIK
What are the official names of this protein?
UPF0716 protein YtzA.
What is the protein family that this protein belongs to?
Belongs to the UPF0716 (FxsA) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: WDR74_MOUSE
Sequence: MATASARWNHVWVGTETGILKGVNLQRKHAANFTPSGQPRREEAVNALCWGTGGETQILVGCADRTVRYFNAEEGTFLSQRYCPGGEGTFRGLAQADGTLITCVDSGILRVWCENDKEASSDPLLELKVGPGVCRMRQDPTHTHVVATCGKENALKVWDLQGSEEPVFRAKNVRNDWLDLRVPIWDQDTQFLPGSQKLVTCTGYHQVRVYDPVSPQRRPVLEATYGEYPLTAMTLTPEGNSVIVGNTHGQLAEIDFRQGRLLGCLKGLAGSVRGLQCHPSKPLLASCGLDRVLRIHRIRNPRGLEHKVYLKSQLNCLLLSGRDNWEDEPQEPQEPNQVPSEDTETDELWASLEAAAKRKLPDLDQTQGALQRRKKKKRPGSTSP
What is the function of this protein?
Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit.  Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity).  Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (PubMed:21799883).
What are the official names of this protein?
WD repeat-containing protein 74.
What are the subcellular locations of this protein?
Nucleus, nucleolus. Nucleus. Note=Nucleolar location depends on active PolI transcription of pre- rRNA.
Protein: LEPA_FRAP2
Sequence: MKNIRNFSIIAHIDHGKSTLSDRFIQVCNGLSEREMKEQVLDSMDIERERGITIKAQSVTLDYVARDGQTYQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQTVANCYTAIEQNLEVIPILNKIDLPSAEPDRVAEEIEEIIGIDATGATTCSAKTGIGVEDVLETIVAKVPAPEGDVNAKLQALIIDSWFDNYLGVVSLVRIKNGTLKKGEKFKVMSTGVSYQVDRVGVFTPKMKDLDHLKAGEVGFIVAGIKDIHGAPVGDTLTHTHNPTDKPVPGFKKVQPQVYAGMFTISSDDYPDFREALDKLSLNDASLFFEPEVSQALGFGFRCGFLGMLHMEIIQERLEREYNLDLITSAPTVVYKAVKKDGETIDVDSPSKLPEPGAIAEIHEPIVRANILVPKDYVGSVITICVEKRGVQVDLNYVGSQVSITYDLPMIEVVSDFFDTLKSVTKGYGSLDYELIRYEAADMVRLDVLINGDKVDALASIVHKDQAKYKGRELVERLKELIPRQMFEVAIQAAIGGTIVARSTVKALRKNVLAKCYGGDVSRKKKLLEKQKEGKKRMKNIGSVEIPQEAFLSVLKK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: SYT_CHLTR
Sequence: MIHVTCNQEAFELPEGASAMDLANKMKQSHCFAGALINDQEKDLSTTLQDGDTVLFLTWDDPKGREIFLHTSAHILAQAVLRLWPSAQPTIGPVIDQGFYYDFANLSISEEDFPAIEAMAKTIAEEKFPISRQVFPDKEAALAYFSQNPFKAELIAELPEEVEISAYTQGEFLDLCRGPHLPSTAPVKAFKLLRTSSAYWKGDPSRESLIRIYGVSFPTTKELKEHLHQLEEAKKRDHRVLGTKLDLFSQQTCSAGMPFFHPRGMVVWNALVDYWKRLHQRAGYQQIQTPQLMNRELWEISGHWENYKENMYTLTVDEEDYAIKPMNCPGCMLYYKTQLHSYREFPLRIAEIGHVHRHELSGALSGLMRVRTFHQDDAHVFLTPEQVEEETLNILNLVSELYGTFGLEYHLELSTRPEQGTIGSDDLWELATKALKRALVKSQKPFIISPGEGAFYGPKIDIHVKDAINRTWQCGTIQLDMFLPERFDLKYTNAQGEKSTPIMLHRALFGSIERFLGILIEHFKGRFPLWLSPEHVRIITVADRHEARAQELAKHFSQMGIIVSVDSSNESVSKKIRNAQNMQVNYMITIGDKELETHLLAVRTRDNRVLNDIAVEQFSHVILEELRSLSLTPSL
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: OTNC_HAEIN
Sequence: MTDLAQKELMVQLGRSFYERGYTVGGAGNLSVRLDDNRVLVTPTGSSLGRLSVERLSVLDMEGNLLGGDKPSKEAVFHLAMYKKNPECKAIVHLHSTYLTALSCLDNLDPNNAIEPFTPYYVMRVGKMQVIPYYRPGSPKIAEELSNRALTGKAFLLANHGVVVTGSDLLDAADNTEELEETAKLFFTLQGQKIRYLTDTEVKDLENRGK
What is the function of this protein?
Catalyzes the decarboxylation of 3-oxo-tetronate 4-phosphate to dihydroxyacetone phosphate (DHAP) and CO(2).
What are the official names of this protein?
3-oxo-tetronate 4-phosphate decarboxylase.
What is the protein family that this protein belongs to?
Belongs to the aldolase class II family. AraD/FucA subfamily.
Protein: KDTA_RICBR
Sequence: MMRLYYFLSFLLLPIYFVIIFIRLLIGKEDIRRVKERFAIGKHRQDNRFLIWIHAASVGESMIALNLVDNISKHFPEVRFLVTSWTQSSAKILSTKLPKIATHQLLPIDNIIFTKIFLNNWKPDLGIFIESELWPGTINEAAKQCNLLLVNARMSDKSFESWKKRKGFFQLIVKNFSEVIVQSERDLQKFNELGISNTTNLGNIKFANEKLPVNQEELIKLSEHLKNKQVILFASTHPEDEEIILPIIKNLKKQVIDCYIILIPRHPERIKSILDNCIAQDLSATAKSQNDLPVLTDDLYIVDRFGEMGLFFSIASISFIGGSFKQGGHNILEAAHFSNCIIFGPDMSKNTDIAKGVLQSKAAIQIKSGEELLNMLEYLLDPNNSRELKNYQENSLKFVERNQKILDEYLQIITKFFP
What is the function of this protein?
Involved in lipopolysaccharide (LPS) biosynthesis.  Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.
What are the official names of this protein?
3-deoxy-D-manno-octulosonic acid transferase, Kdo transferase, Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 30 subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein; Cytoplasmic side.
Protein: SELO_JANSC
Sequence: MPDAFPFDNTYASLPDRFFTRMSPKPVAEPGLIAVNRPLAERLGITLGESDAELAQLFAGNVVPMGAAPLAQVYAGHQFGGWSQQLGDGRAVMLGEVVAPDGARFDVQLKGAGQTPYSRMGDGRAWLGPVLREYIVSEAMAALGIPTTRALAAVTTGEIVLREARMPGAVLTRVAASHIRVGTFQYFAARQDVDALQALLDHTIARHYPDVDGPSGLLDAALQAQADLIAKWMGVGFIHGVMNTDNMTLSGETIDYGPCAFMDTYEANKVFSSIDQFGRYAYAQQPQIAAWNLAQLATALLPLMPDRDAAIEEFTEAVNGFAARFDTAWHGVLRAKLGLVSEQEGDAQLAFDLLNRMEQGGGDFTQVFRALSGPEPERAAEAFAAPAVLAPWLKAWRARLARDNVAKAARIASMQADNPALIPRNHRIEEVIQAAVKGDFAPFERLTTALQDPFTDRPEFADLQATPARSEAVTQTFCGT
What is the function of this protein?
Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).
What are the official names of this protein?
Protein adenylyltransferase SelO.
What is the protein family that this protein belongs to?
Belongs to the SELO family.
Protein: CDS1_YEAST
Sequence: MSDNPEMKPHGTSKEIVESVTDATSKAIDKLQEELHKDASESVTPVTKESTAATKESRKYNFFIRTVWTFVMISGFFITLASGHAWCIVLILGCQIATFKECIAVTSASGREKNLPLTKTLNWYLLFTTIYYLDGKSLFKFFQATFYEYPVLNFIVTNHKFICYCLYLMGFVLFVCSLRKGFLKFQFGSLCVTHMVLLLVVFQAHLIIKNVLNGLFWFLLPCGLVIVNDIFAYLCGITFGKTKLIEISPKKTLEGFLGAWFFTALASIILTRILSPYTYLTCPVEDLHTNFFSNLTCELNPVFLPQVYRLPPIFFDKVQINSITVKPIYFHALNLATFASLFAPFGGFFASGLKRTFKVKDFGHSIPGHGGITDRVDCQFIMGSFANLYYETFISEHRITVDTVLSTILMNLNDKQIIELIDILIRFLSKKGIISAKNFEKLADIFNVTKKSLTNHS
What is the function of this protein?
Supplies CDP-diacylglycerol, which may play an important role as both a precursor to phosphoinositide biosynthesis in the plasma membrane and as a negative effector of phosphatidylinositol 4-kinase activity, thereby exerting an effect on cell proliferation via a lipid-dependent signal transduction cascade.
What are the official names of this protein?
Phosphatidate cytidylyltransferase, CDP-diacylglycerol synthase, CDP-DAG synthase, CDS, CDP-diglyceride pyrophosphorylase, CDP-diglyceride synthase, CDP-DG synthase, CTP:phosphatidate cytidylyltransferase.
What is the protein family that this protein belongs to?
Belongs to the CDS family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle. Note=Exclusively present in the ER, and not in mitochondria. Also associated with post-Golgi apparatus secretory vesicles destined for the plasma membrane.
Protein: FOLE_YEAS8
Sequence: MHKGKKNYPNLITSFRMNLKKIILNHDRFSHPERWKTNALLRFTFVYIKFLFDLMIIKNPLRMVGKTYRDAVTALNSLQSNYANIMAIRQTGDRKNTMTLLEMHEWSRRIGYSASDFNKLNIVHITGTKGKGSTAAFTSSILGQYKEQLPRIGLYTSPHLKSVRERIRINGEPISEEKFAKYFFEVWDRLDSTTSSLDKFPHMIPGSKPGYFKFLTLLSFHTFIQEDCKSCVYEVGVGGELDSTNIIEKPIVCGVTLLGIDHTFMLGDTIEEIAWNKGGIFKSGAPAFTVEKQPPQGLTILKERAEERKTTLTEVPPFKQLENVKLGIAGEFQKSNASLAVMLASEILHTSNILEEKIKCSSNASIPEKFIIGLQNTKWEGRCQVLEKGKNVWYIDGAHTKDSMVAASTWFRDMVRLSKRKKILLFNQQSRDANALVNNLYSSVSPEITFDDVIFTTNVTWKSGSYSADLVSMNTSQEDVEKLKVQESLVKNWNKIDDNRAKTHVTASIEEANELIETLYDEPADIFVTGSLHLVGGLLVVFDRIDVK
What is the function of this protein?
Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.  Required for methionine synthesis and maintenance of intact mitochondrial DNA.  Involved in telomere maintenance (By similarity).
What are the official names of this protein?
Folylpolyglutamate synthase, Folylpoly-gamma-glutamate synthetase, FPGS, Tetrahydrofolylpolyglutamate synthase, Tetrahydrofolate synthase.
What is the protein family that this protein belongs to?
Belongs to the folylpolyglutamate synthase family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane. Mitochondrion matrix. Cytoplasm.