PharMolix/UniProtQA huggingface dataset:
Protein: CRR50_ARATH
Sequence: MSSVFGSVHILAMIAIQLLLTHSVSSLNLTNAYLHHKCSNTQGKYKQGSAFEKNLNLVLSTITSIGNFRDGFRYTEEGEDPNNVFVMFQCRGDSYWSKCPPCISTAVSGLRRRCPRNKGAIIWYDQCLLKISSVASFNKIDYENDFYLSNPNNMSDRGLFNKETSALLEKLAYKASDRNNLDGKQLVLYAAGEKRIGTKKVYAMVQCTKDLIFTKCFECLEGILRKFPQCCDGKRGGRVFGTSCNFRYELYPFLRN
What are the official names of this protein?
Cysteine-rich repeat secretory protein 50.
What is the protein family that this protein belongs to?
Belongs to the cysteine-rich repeat secretory protein family.
What are the subcellular locations of this protein?
Secreted.
Protein: LDH_PLABE
Sequence: MAPKAKIVLVGSGMIGGVMATLIVQKNLGDVVMFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNTYDDLKDADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNNCPNAFIIVVTNPVDVMVQLLHQHSGVPKNKIVGLGGVLDTSRLKYYISQKLNVCPRDVNAHIVGAHGNKMVLLKRYITVGGIPLQEFINNKKITDQELDAIFDRTINTALEIVNLHASPYVAPAAAIIEMAESYIRDLRKVLICSTLLEGQYGHKDIFAGTPLVIGGNGVEQVIELQLNADEKKKFDEAVAETSRMKALI
What are the official names of this protein?
L-lactate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the LDH/MDH superfamily. LDH family.
Protein: KU80_SCHPO
Sequence: MSDKECTVFVLDLGKDMGTCHHGRSHSDLEWTLSYFHDELSHKFLANRKTDVVGIVGYKCDDTKNDLAEQEAYWNISVLYPIQTALFSKLQSVSQTLKPSNTMQGDLISAIVVSFDLMARHCKKNKWKKKMIVLTAARGIIDFSDYIGIAEQLLQHDVFLGVYGVDFDQEDINYSEPLKESQKKENEVRIQEFVESCHGQYCTFQQIYNNIGKPWVRKVRPVAIFRGTFSIGNRDSKDTSISIQVERYPRTRLTKPPTSSAFYENDMSKNYECLNIENSNVENKSMESDAVSTVRSYMVRDPKTNDSFEVKREDLESGYSYGRTIVPISRSDEDVLALDTIPGYEILGFIPKSSLPIYYTISDTNIIVPKDDFESKLNFSAFVQSLEREHRYALARFVSKDKGVPVLLVLMPYVEFKRHYLVDIQLPFAEDVRPYSFSEFEKLSNEEDMRQIDFAVSNYIDNMDLDSSDCGFNPPFEPENTFSMIPHRLQQAISYYANSPEGDLPQPNIYLTRYTNPPKSLLDNCILDLKLIKEKLTVNVPVKPKYSSQETAFDTGAPISEEQIEELLNSGLDEQEGEKLLVLHVSEKDPVGTFTEVLKNPFGLEDALTEMEKVIKNLIDKSKYDLALQSLQSLRLHSILEDEVERFNEYLTRLKKDVMQNNKPKENELINKIRSSGLDIILHDELTRHDNFNNI
What is the function of this protein?
Single-stranded DNA-dependent ATP-dependent helicase.  Involved in non-homologous end joining (NHEJ) DNA double strand break repair.  DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA.  Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection.  Required also for telomere recombination to repair telomeric ends in the absence of telomerase.  ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase.  Involved in telomere maintenance.  Interacts with telomeric repeats and subtelomeric sequences thereby controlling telomere length and protecting against subtelomeric rearrangement.  Maintains telomeric chromatin, which is involved in silencing the expression of genes located at the telomere.  Required for mating-type switching (By similarity).
What are the official names of this protein?
ATP-dependent DNA helicase II subunit 2, ATP-dependent DNA helicase II subunit Ku80, Pombe Ku80.
What is the protein family that this protein belongs to?
Belongs to the ku80 family.
What are the subcellular locations of this protein?
Nucleus. Chromosome, telomere.
Protein: TRMFO_DICT6
Sequence: MEKVKIIGGGLAGSEAAWQLAKRKIPVEIYEMRPVVTTPVHKTEYLAELVCSNSFKSTELTNASGLLKEEMKKLDSLLLRVAEETRVPAGVALAVDRELFAKRVQEILLESPYVTVIREEVKKIPEEGIVIVATGPLTSSDFAEHLIEILDTDSLYFYDAVSPIIYADSINYEKVFSASRYGKGEEAYLNCPMTKEEYERFVEELVNAETVESHYPGEEKFFEGCLPIEVLARRGIDTLRYGPMKPVGLIDPKTGKEPYAVVQLRPENIQKTLYSMVGFQTRLKFQEQRRIFRMIPGLENAEFARYGVMHRNTYFYAPKFLKPTLQFIKNERVFFAGQLIGVEGYMESAAMGIVAGINAARLYKGKPLIILPPTTMIGALISYVTTKVPVKQFQPMNANWGILLPLERPVKDKKLRNRLLAERALRDLDDVIRRFAINV
What is the function of this protein?
Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.
What are the official names of this protein?
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO, Folate-dependent tRNA (uracil-5-)-methyltransferase, Folate-dependent tRNA(M-5-U54)-methyltransferase.
What is the protein family that this protein belongs to?
Belongs to the MnmG family. TrmFO subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CICE_EMENI
Sequence: MERFPRSAADAQQLLQLAELFKQSAEIIAEEWNKEDFSRIKAETNSIKSNLGSLDTARILPSPRLHEATRTVLAITGAATELVAEPYSRIQEVACQYFESRALFVAAERRIPDLLAGAGEYGLSVGEIAEATGIEERKLSRILRCLCSIHIFRQIGTDRFANNRISAALKNNEPLRAYVQLFNLDIYTASDQLPKYLLSSQGASYKVHETAWQKAVGTTKARWDWLAERVSLDEVRPKEAPYPGLPDVRHLQPGPDGKYARPELDNFGLAMVGGGKVSGAAHAYDFPWASLGDALVVDVGGGVGGFVLQLLPAYPQLRYIVQDRAEVLQQAQEEIWPVEAPEAVADGRVQFMEHNFFQPNPVKGADVYWLRGIFYCVQILSALRTSMAPTSRILVCDQVMNTTAGCDEIPPAPSPLPANYGYYMRYPHHRDLAMMSIINGIERTPAQFTELVKQAGLKVNKIWNCRSMVGIVEIGLKNEKDRHHRRLSYMGFGNYTQLGIGFFSSAKGPVRDELQADEQA
What is the function of this protein?
O-methyltransferase; part of the gene cluster that mediates the biosynthesis of cichorine, a phytotoxin active against knapweed, corn, and soybeans (PubMed:24244835).  The first step in the pathway is performed by the non-reducing polyketide synthase pkbA that condenses one acetyl-CoA starter unit with 3 malonyl-CoA units (PubMed:22510154).  PkbA also catalyzes one methylation step to produce 3-methylorsellinate (PubMed:22510154).  The nonribosomal peptide synthase-like protein cicB, the cytochrome P450 monooxygenase cicH and the O-methyltransferase cicE are involved in the conversion of 3-methylorsellinate into nidulol (PubMed:24244835).  CicB converts 3-methylorsellinate to a yet unidentified intermediate, cicH may play a ring-closing role for cichorine and cicE is plausibly responsible for the methylation of one of the phenol groups (Probable).  The oxidoreductase cicC acts downstream with still unidentified enzymes to further convert nidulol into cichorine (PubMed:24244835).
What are the official names of this protein?
O-methyltransferase cicE, Cichorine biosynthesis cluster protein E.
What is the protein family that this protein belongs to?
Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-independent O-methyltransferase family.
Protein: FENR_STRPB
Sequence: MKDKAYDITIIGGGPIGLFAAFYAGLRGVTVKIIESLSELGGQPAILYPEKMIYDIPAYPSLTGVELTENLIKQLSRFEDRTTICLKEEVLTFDKVKGGFSIRTNKAEHFSKAIIIACGNGAFAPRTLGLESEENFADHNLFYNVHQLDQFAGQKVVICGGGDSAVDWALALEDIAESVTVVHRRDAFRAHEHSVELLKTSTVNLLTPYVPKALKGIGNLAEKLVIQKVKEDEVLELELDSLIVSFGFSTSNKNLKNWNLDYKRSSITVSPLFQTSQEGIFAIGDAAAYNGKVDLIATGFGEAPTAVNQAINYIYPDRDNRVVHSTSLID
What are the official names of this protein?
Ferredoxin--NADP reductase, FNR, Fd-NADP(+) reductase.
What is the protein family that this protein belongs to?
Belongs to the ferredoxin--NADP reductase type 2 family.
Protein: GLYL3_MOUSE
Sequence: MLVLKCSTKLFILENMLKSHFPESLKVYGAVMNINRGNPFQKEVVLDSWPNFKVIITRREREAETDNLDHYTNAYAVFYKDIRAYQQLLEEHDVINWDQVFQIQGLQSELYAASKAVAKARLLDLDINLASFKAVHFSPVSSVPDHSFLTGPTPRLTYLSVSDADLLNRTWSRGGNQQCLRYLANLIACFPSVCVRDEKGNPVSWGITDQFATMCHGYTLPDHRRKGYSRLVALTLARKLQSRGFPSQGNVLDDNLASINLLKSVQAEFLPCRFHRLILTPAAFSRQAHL
What is the function of this protein?
Catalyzes the conjugation of long-chain fatty acyl-CoA thioester and glycine to produce long-chain N-(fatty acyl)glycine, an intermediate in the primary fatty acid amide biosynthetic pathway.
What are the official names of this protein?
Glycine-N-acyltransferase-like protein 3, Acyl-CoA:glycine-N-acyltransferase-like protein 3.
Protein: VAPB4_MYCTU
Sequence: MSATIPARDLRNHTAEVLRRVAAGEEIEVLKDNRPVARIVPLKRRRQWLPAAEVIGELVRLGPDTTNLGEELRETLTQTTDDVRW
What is the function of this protein?
Antitoxin component of a type II toxin-antitoxin (TA) system.  Antitoxin that counteracts the effect of its cognate VapC4 toxin.  Upon expression in situ, in M. smegmatis or E. coli neutralizes the effect of cognate toxin VapC4.
What are the official names of this protein?
Antitoxin VapB4, VapB-mt4.
What is the protein family that this protein belongs to?
Belongs to the phD/YefM antitoxin family.
Protein: GCSH_AERPE
Sequence: MGGQVIEVEVAGVRFLLRKDLRYTESDEWARLEDGVATVGITDFAQKELKDIVGVELPEKGRKVKKGEAVATVESIKATADIYAPLSGEIVDVNEKLLDQPELINDDPYGEGWIFKIKVEDPGEFESLLTPEQYVESVRKRKE
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Probable glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: SAT_DESRM
Sequence: MALVQPHGGKLTPVLAPKEQRAELKAKAEKLPVIRMSSRESSDCLMLGMGAFSPLTGFMTQADYQGVIDNMHLASGLAWPLPVTLAVTKDQAASIEVGQELALVDDETDIYVGIIKVADKYEYDKVKECKATFFTDDADHPGVQKVMSQGEVYLGGDIVTFSEMGYATKYAGYYAHPAETRALFESKGWSTVCAFQTRNPLHRSHEFLCKIGNEVCDGLFLHPIVGKLKKGDIPAEVRFECYKAHMENYFNPATIEMRVYPMEMRYAGPKEAILHAIFRQNFGCSHILVGRDHAGVGSYYTAYQAQEIFDEFKPGEILCQPIKVTASYYCKKCMGMATEKTCPHTKEDRIAISGTKVREMFSKGELPPLEFGRKEVLEILTKYYQSLEK
What are the official names of this protein?
Sulfate adenylyltransferase, ATP-sulfurylase, Sulfate adenylate transferase, SAT.
What is the protein family that this protein belongs to?
Belongs to the sulfate adenylyltransferase family.
Protein: F90AF_HUMAN
Sequence: MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDKGEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPKERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQACLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLENGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE
What are the official names of this protein?
Putative protein FAM90A15P.
What is the protein family that this protein belongs to?
Belongs to the FAM90 family.
Protein: RL18_ROSS1
Sequence: MAKRTPRELRIRRHRRVRKKVHGTPQRPRLCVFRSNMHIYAQVIDDTVGRTLAAASTVEPELRASLTGKTKTEQAKAVGAVIAERARAAGIERVVFDRGGFKYHGRVQALADAARAGGLQF
What is the function of this protein?
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
What are the official names of this protein?
50S ribosomal protein L18.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL18 family.
Protein: CYB_CTECO
Sequence: MNNTRKSHPLIKIVNHSFIDLPTPSNISAWWNFGSLLGVCLGLQILTGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFIFLYFHIGRGIYYGSYTFMNTWNIGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGPTLVEWIWGGFSVDKATLTRFFAFHFILPFIITAMVMIHLLFLHETGSNNPSGMNSDSDKIPFHPYYTIKDVLGVLFMMITLMSLVMFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVSSILILMLFPIMHSSKQRSMSFRPFSQCLMWLLVANLFILTWIGGQPVEYPFIIIGQLASVTYFFTILILMPSMALMENKLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: RS7_LACLS
Sequence: MRKNRAPKREVLADPMYNSIVVTRLINRVMLDGKRGVAAQIVYGAFKQIEEATGNNPLEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLRWLVTIARNRGEHTMQDRLAKEILDAANNTGAAVKKREDTHKMAEANRAFAHFRW
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit.  Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
What are the official names of this protein?
30S ribosomal protein S7.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS7 family.
Protein: SSRP_FRATT
Sequence: MSKHKVSPATIAKNKKALHDYTILEKFEAGIVLQGWEVKSIRAGKVQMVDSHVHIKHGEAWLFNCLITPLLSASTHVVADAAATRKLLLNRREINKIMGRIEQKGFTCIPLSMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRLFKKAYK
What is the function of this protein?
Required for rescue of stalled ribosomes mediated by trans-translation.  Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes.  tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB.  tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame.  During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA.  The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation.  The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.
What are the official names of this protein?
SsrA-binding protein, Small protein B.
What is the protein family that this protein belongs to?
Belongs to the SmpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=The tmRNA-SmpB complex associates with stalled 70S ribosomes.
Protein: ADE_CUPNH
Sequence: MTIDAALAEQIRRTPKAELHVHIEGTLEPELIFRLAQRNQVALPYPSVEALRAAYAFTDLQSFLDIYYAGASVLLTEEDFFDMTMDYVKRAVADNVRHAEIFFDPQTHTARGVPIGVVIDGIADALAQARTEYDFSSSLILCFLRHLPEEDAFATLEAALPYRDRFVGVGLDSSERGNPPEKFARVFARARELGLHLVAHAGEEGPAQYVTDALDILKAQRIDHGVRAIDDPALVERLARERVALTVCPLSNVKLKVYPDLRDHPLKRMLDAGVVITLHSDDPAYFGGYMNANWEATFEALPLDAADAHKLARNSFEAAFLPAMQKAEFLAEVDHFWSSPPKSPPATAPAA
What is the function of this protein?
Catalyzes the hydrolytic deamination of adenine to hypoxanthine.  Plays an important role in the purine salvage pathway and in nitrogen catabolism.
What are the official names of this protein?
Adenine deaminase, ADE, Adenine aminohydrolase, AAH.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
Protein: UBIA_ECOL6
Sequence: MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
What is the function of this protein?
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group.  Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
What are the official names of this protein?
4-hydroxybenzoate octaprenyltransferase, 4-HB polyprenyltransferase.
What is the protein family that this protein belongs to?
Belongs to the UbiA prenyltransferase family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: LEPA_IDILO
Sequence: MPNRAFKQSNIRNFSIIAHIDHGKSTLSDRLIQHCGGLTDREMAEQVLDSMDLERERGITIKAQSVTLYYTAKDGETYQLNFIDTPGHVDFSYEVSRSLAGCEGALLVVDAAQGVEAQTLANCYTAIEMDLEVVPVLNKIDLPQADAMGVAQEIEDIVGIEAVDAVQCSAKTGLGIDDVLERIVRQIPPPKGEPEEPLQALIIDSWFDNYQGVVSLVRVRNGTLRAGEKMTVMSTGQSYQIDKVGYFDPKPHETGILHTGEVGYVISGIKDILGAPVGDTLTNTKSPAKEPVPGFKKVKPQVYAGMFPISSEDYESFRDALGKLSLNDASLFYEPENSAALGFGFRCGFLGMLHMEIIQERLEREYDIDLITTAPTVVYEVEKTDGSIVKVDNPVNLPAVNDIETIYEPIVEANILVPQEFLGNVITLCVDKRGVQTAMAYHGKQVAVTYELPMAEVVMDFFDRLKSTSRGYASLDYQFKKFEPADMVRVDILINGDRVDALAMITHRDHAEGRGRMLVDKMRELIPRQMFDIAIQATIGNHVIARSTVKQLRKNVTAKCYGGDISRKKKLLQKQKEGKKRMKNLGNVEVPQEAFLAVLKVGK
What is the function of this protein?
Required for accurate and efficient protein synthesis under certain stress conditions.  May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes.  Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly.  Binds to ribosomes in a GTP-dependent manner.
What are the official names of this protein?
Elongation factor 4, EF-4, Ribosomal back-translocase LepA.
What is the protein family that this protein belongs to?
Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: ISPE_NOVAD
Sequence: MQEASGLAPAPLPFQGRAMSLRETAYAKINLALHVRRRRDDGYHELETLFAFVDAGDELTAKPAPADSLRVFGEFGGALDDPFGNIVAKALGTLPHGEGWAVTLEKHLPVAAGLGGGSADAGAVFRMVERSHGLPADWHARAARLGADVPACVESAACIGRGTGTELEPIPNDLAGTPVLLVNPRIPLATGPVFKAWDGVDRGALEGATAREVAFAGRNDLEAPALSLVPEIGAVLVTLRQTGGWLTRMSGSGATCFALYDTPEQRDLAQAAMPPSWWTLGGALR
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: RIMP_TREPA
Sequence: MNFSPNTLGSFESCAEVVRSLGCALVDLQWSVSAVSRRVQQAQGRARAVIYSAGGVTLDVCARVHRILVPRLQALGGVRTVFLEVGSPGERVIRNAAEFSIFLGETVKVWFCTGQFQVGTLAFADETCLTLTAGGVPVTIPYVQLTKAQLHPAVRA
What is the function of this protein?
Required for maturation of 30S ribosomal subunits.
What are the official names of this protein?
Ribosome maturation factor RimP.
What is the protein family that this protein belongs to?
Belongs to the RimP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: TRUA_ACIET
Sequence: MRMALGVSYNGQAYNGWQSQPSGNTVQDRLEAALGRFATQEVHTICAGRTDAGVHGLMQVVHFDTQLQRAPFSWVRGTNTFLPTDIAVQWAQPVPDAFHSRACAVARRYAYVLLQSPVRPSVDAGRVGWVFHALDEQAMHRAVQHLLGEHDFTSFRASACQAKSPVKTLHRIDITRRAPPAGESTGTHGCIPCYWRFEFEGNAFLHHMIRNIMGCIVAIGQGLYPPEWMRTVLEARSRDAAAPTFSPDGLYFQGPVYGAEWGLPTRTAAYDWLP
What is the function of this protein?
Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
What are the official names of this protein?
tRNA pseudouridine synthase A, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I.
What is the protein family that this protein belongs to?
Belongs to the tRNA pseudouridine synthase TruA family.
Protein: MUKF_SALPK
Sequence: MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAAEGGDEFHWHRNVYAPLKYSVAEIFDSIDLTQRIMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDDPWALTYANADRLLDMRDEEMALRDDEVTGELPPDLEYEEFNEIREQLAAIIEEQLAIYKTRQTPLDLGLVVREYLAQYPRARHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
What is the function of this protein?
Involved in chromosome condensation, segregation and cell cycle progression.  May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.  Not required for mini-F plasmid partitioning.  Probably acts via its interaction with MukB and MukE.  Overexpression results in anucleate cells.  It has a calcium binding activity.
What are the official names of this protein?
Chromosome partition protein MukF.
What is the protein family that this protein belongs to?
Belongs to the MukF family.
What are the subcellular locations of this protein?
Cytoplasm, nucleoid. Note=Restricted to the nucleoid region.
Protein: MNMA_VIBVU
Sequence: MSDNSQKKVIVGMSGGVDSSVSAYLLKQQGYQVEGLFMKNWEEDDDSEYCTAAEDLADAQAVCDKLGIHLHKINFASEYWDNVFEYFLAEYKAGRTPNPDILCNKEIKFKAFLEFADEVLDADYIAMGHYVRRSFPENGEKPQMLRGLDGNKDQSYFLYTLSHEQVARSLFPVGDLEKPEVRRIAEEQGLITAKKKDSTGICFIGERKFTDFLSRYLPAQPGNIESPEGEVLGQHQGLMYHTLGQRKGLHIGGRKGGGGNEEPWFVAEKDLKRNVLIAVQGQDHPMLKSEGLIASQLHWVEREPIRDVVKCTVKTRYRQQDIPCTIIPIDDENIKVIFDEPEIAVTPGQSAVFYQGDVCLGGGIIEKRIKYTQA
What is the function of this protein?
Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
What are the official names of this protein?
tRNA-specific 2-thiouridylase MnmA.
What is the protein family that this protein belongs to?
Belongs to the MnmA/TRMU family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: KIZ_CHICK
Sequence: MSEAGRAAAGPCPEVSPSRSQQLGGLLRCLRDSETRRLELERKLMEYKSSDAYLMKLKYVKLKKYLEEVNERQKRALLRNQTFLNEFNEFEAHVKASSSELIEKMVRYGREIKSGLSFQEGDLARGDKEEGCNEQMPQAARQAGIHAKTALSRSLHHPVPFFMGHCMSACSVQQETPQPAACPNSLTALQGDETDGHPTQADDDMQHANKLDEQGGKSYVPMGEKMSIRDSSLHSSLLNFTERKNSTELCSALPDGGSLQSRTADLASDTSVEEVVTREHLVASAKEVCEQPVLLASAPEPSITGPQCNLNTQQAASQDSSSSSTHPEENYSLQPPSCCAAEDEPLGSSVPEGFCSQDGSLKEDLEASEAAVLCQLPEAKSGQQWDVATLQASLNSHTAFLEEHEHLCTEELAAVLHSTLDLDEEAPGSQAPPLLREVLAEECGDGSSVQSNESSYSLPSIPNDSREVEQAKHVLWLDSMGKQGCVIGNNGSEAKESQEMCSERSSSSERSGDLSRPEFRKGAITAIKSKAFWGESDDSSSEAVDALRPQTRSPEADDFDDFYD
What is the function of this protein?
Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation.  Required for stabilizing the expanded pericentriolar material around the centriole.
What are the official names of this protein?
Centrosomal protein kizuna, Polo-like kinase 1 substrate 1.
What is the protein family that this protein belongs to?
Belongs to the kizuna family.
What are the subcellular locations of this protein?
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body.
Protein: GSA_SHEB2
Sequence: MTRSEALFEQAKKTIPGGVNSPVRAFNGVGGSPLFIEKANGAYIYDADGKAYIDYVGSWGPMILGHNHPKIRAAVLAAVENGLSFGAPTELEVQMAEKVISMVPSIEQVRMVSSGTEATMSAIRLARGFTNRDKILKFEGCYHGHADCLLVKAGSGALTLGQPSSPGIPEDFAKHTLTAVYNDLDSVRTLFEQYPTDISCIIIEPVAGNMNCIPPIPGFLQGLRDICDEFGALMIIDEVMTGFRVSQSGAQGYYGVTPDLTTLGKVIGGGMPVGAFGGRKDVMQFIAPTGPVYQAGTLSGNPIAMSAGLAQMEALCEEGLYEELSAKTKRIAEGFKAAADKHGIPMAINYVGGMFGFFFTEQPEITRFDQVTQCNIEQFRIFYHGMLDEGVYLAPSAYEAGFLSMAHGEEEMRLTLEAADRVLASMKAAS
What are the official names of this protein?
Glutamate-1-semialdehyde 2,1-aminomutase, GSA, Glutamate-1-semialdehyde aminotransferase, GSA-AT.
What is the protein family that this protein belongs to?
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: MIAA_AZOC5
Sequence: MGLRDSEALKPLAVLIAGPTASGKSALALDLAERTDGVIINADSMQVYGDLRILTARPSPEEEMRVPHRLYGHVDGAADYSVARWIADAAAAMATARAEGRLPIVIGGTGLYFRALTRGLAPIPEIPEEVRQRVRRMAEDEVTVVLHARLATRDPEAAVRLQPQDRQRILRALEVFEATGQPLSQWQRATHRPVLEEASAVRFVLEVERETLRGRIDRRFETMMEAGALAEVERLAARELPADRTILKAHGAPALTRYLRGEMSRADAIAEGQNDTRRYAKRQVTWFRHQMPDWMRGTPDTALDQLTGTLRL
What is the function of this protein?
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
What are the official names of this protein?
tRNA dimethylallyltransferase, Dimethylallyl diphosphate:tRNA dimethylallyltransferase, DMAPP:tRNA dimethylallyltransferase, DMATase, Isopentenyl-diphosphate:tRNA isopentenyltransferase, IPP transferase, IPPT, IPTase.
What is the protein family that this protein belongs to?
Belongs to the IPP transferase family.