PharMolix/UniProtQA huggingface dataset:
Protein: SHL_ARATH
Sequence: MPKQKAPRKQLKSYKLKHINKSIQEGDAVLMRSSEPGKPSYVARVEAIETDARGSHAKVRVRWYYRPEESIGGRRQFHGAKEVFLSDHFDFQSADTIEGKCKVHSFSSYTKLDSVGNDDFFCRFEYNSTTGAFDPDRVTVFCKCEMPYNPDDLMVQCEECSEWFHPSCIGTTIEEAKKPDNFYCEECSPQQQNLHNSNSTSNNRDAKVNGKRSLEVTKSKNKHTKRPG
What is the function of this protein?
Chromatin remodeling factor that binds to methylated histone (e. g.  H3K4me2/3) to prevent their acetylation (e. g.  H3K9K14Ac), likely by recruiting histone deacetylase (HDAC) complexes, and thus regulate the transcription of target genes (PubMed:25281686).  Required during development and for fertility, probably by modulating developmental gene expression (PubMed:11129039, PubMed:15082927, PubMed:25281686).  Promotes development speed, but at fitness cost (PubMed:11129039).  Involved in the chromatin-mediated repression of floral initiation and controls genes regulating flowering.  Negatively regulates the expression of the floral integrator SOC1, by preventing high levels of H3 acetylation, thus maintaining an inactive chromatin conformation (PubMed:25281686).
What are the official names of this protein?
Chromatin remodeling protein SHL, Protein SHORT LIFE.
What is the protein family that this protein belongs to?
Belongs to the SHL1/EBS protein family.
Protein: SECB1_GLUOX
Sequence: MSENTTDNAALGQENVPAMPLAINLQYTKDLSFEVPAGASIFATLRSAPQISVNIDVQANRLEEDQAVYEVALAVRAEAAEPPAQEGGQAGRTVFIAELTYAAVVTLNNPPQELIEPILLVEVPRLIFPYVRSIVSDVTRDGGFPPVVLQPIDFVALWQAKRAQQFPEPAGEA
What is the function of this protein?
One of the proteins required for the normal export of preproteins out of the cell cytoplasm.  It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state.  It also specifically binds to its receptor SecA.
What are the official names of this protein?
Protein-export protein SecB 1.
What is the protein family that this protein belongs to?
Belongs to the SecB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPE_FRATT
Sequence: MANIKAKKYYSYAKINLFLHILNKRPDGYHNLQTWFTFLDLKDQLTFSFNNSREINISSNISIAAKQDNLVYKAIKKFQQSYRVQDIGVDIEIKKNIPMGAGLGGGSSNAATTLIALRDYYLPQLSNEEMIPLAAKLGADVPIFVYGKSAWAEGIGEILYHKDFSPQYALLIKPDIHISTKEFFTSEDLIKSSVLISKDLGFDKSIMHNDFENVFYAKYPEFSQYLKELDSDFRMTGTGSCFYLLSADKNKLEQLARKINKPLDKWLVKTLNYVY
What is the function of this protein?
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
What are the official names of this protein?
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CMK, 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase.
What is the protein family that this protein belongs to?
Belongs to the GHMP kinase family. IspE subfamily.
Protein: PBGP9_SOLS0
Sequence: MKTFVLHIFIFALVAFASASRDSAKKIGSQYDNYATCLAEHSLTEDDIFSIGEVSSGQHKTNHEDTELHKNGCVMQCLLEKDGLMSGADYDEEKIREDYIKETGAQPGDQRIEALNACMQETKDMEDKCDKSLLLVACVLAAEAVLADSNEGA
What is the function of this protein?
Colony queen number, a major feature of social organization, is associated with worker genotype for Gp-9.  Colonies are headed by either a single reproductive queen (monogyne form) or multiple queens (polygyne form).  Differences in worker Gp-9 genotypes between social forms may cause differences in workers' abilities to recognize queens and regulate their numbers (By similarity).
What are the official names of this protein?
Pheromone-binding protein Gp-9, PBP, Putative odorant-binding protein Gp-9.
What is the protein family that this protein belongs to?
Belongs to the PBP/GOBP family.
What are the subcellular locations of this protein?
Secreted.
Protein: YKOG_BACSU
Sequence: MEKGHILIVEDEEKIARVLQLELEYEGYSVTIKHNGTEGLDAAAEGGYSLVLLDVMLPGLSGLEVLRRLRKTDSQTPVILLTARDSIPDKVTGLDIGANDYVTKPFEIEELLARIRAALRQNGTKTEDIGTFLTYDDLRVNEKTREVRRGDKEVELTPREFDLLVYMLKHPQQVLTREQILSSVWGFDYIGDTNVVDVYIRYIRKKLDYPYEKQLIHTIRGVGYAIKG
What is the function of this protein?
Probable member of the two-component regulatory system YkoH/YkoG.
What are the official names of this protein?
Uncharacterized transcriptional regulatory protein YkoG.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: JZ13C_CHIGU
Sequence: MKTSVLFVIFGLALLFCLSFADELEDTGRQCGEFMWKCGAGKPTCCSGYDCSPTWKWCVLKSPGRR
What is the function of this protein?
Probable ion channel inhibitor.
What are the official names of this protein?
U10-theraphotoxin-Cg1a 3, U10-TRTX-Cg1a, Jingzhaotoxin-13.3, JZTX-13.3, Peptide F5-18.88.
What is the protein family that this protein belongs to?
Belongs to the neurotoxin 10 (Hwtx-1) family. 29 (Jztx-13) subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: RS17_PARDP
Sequence: MPKRILQGKVVSDKNEQTVTVLVERRFKHPLLHKTVRSSKKYRAHDADNQFKVGDTVRIVECAPISKTKRWTVLTETAEVSA
What is the function of this protein?
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
What are the official names of this protein?
30S ribosomal protein S17.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS17 family.
Protein: FOLR2_MOUSE
Sequence: MAWKQTPLLLLVYMVTTGSGRDRTDLLNVCMDAKHHKTKPGPEDKLHDQCSPWKKNACCSVNTSQELHKADSRLYFNWDHCGKMEPACKSHFIQDSCLYECSPNLGPWIQQVDQSWRKERFLDVPLCKEDCHQWWEACRTSFTCKRDWHKGWDWSSGINKCPNTAPCHTFEYYFPTPASLCEGLWSHSYKVSNYSRGSGRCIQMWFDSTQGNPNEDVVKFYASFMTSGTVPHAAVLLVPSLAPVLSLWLPG
What is the function of this protein?
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells.  Has high affinity for folate and folic acid analogs at neutral pH.  Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release (By similarity).
What are the official names of this protein?
Folate receptor beta, FR-beta, Folate receptor 2, Folate-binding protein 2.
What is the protein family that this protein belongs to?
Belongs to the folate receptor family.
What are the subcellular locations of this protein?
Cell membrane; Lipid-anchor, GPI- anchor.
Protein: MUTS_ANAD2
Sequence: MPEIAQAHTPMMRQYLETKARYPDAILFFRLGDFYEMFFEDALTASEALQITLTARSKGDDKVPMCGVPYHAARGYVARLLEKGFKVAICDQVEEPGKSQLVKREVTRVVTPGMVLDDQVLDPREASWLGAVALEDGRAGLALLDASTGQLQCGEVDGDERLVDELRRAGVRELVFSSAADGARTDAIARAAGAPAARRDAAEFDRAEDRLRKHLGVPSLDGFGVSGLPLGLAAAAAALAYLADTQRATPRHVDRISRLSTDDVLLLDEATRTNLELERTLSGGRKKGTLLALLDRTVTAPGGRRLAEWLRYPLTDLARIGARLDAVEELTGAAVAREELALALRPVADLERLLSRLVLGQGNARDLRALAGALLALPALAGVLEARGAARLREAGARLRGLEALAAHLDAAVAEEPPATLREGGFIRRGHSAELDEIVAIAEDGKGWIAAMEAKERERTGIGSLKVRFNKVFGYYLEVTKPNLHLVPKDWERRQTTVGGERFVTPELKTFEEKVLTAEERRAALEERLFEALRQAVAAEAPRVRTAADAVATADALLSLSRVAAERGYVRPEVDASEALEIVDGRHPVVEAVLPDGPAAYVPNDVLVASRGAPECGEHGALLVITGPNMAGKSTVMRQAALVVLLAQMGAFVPARRARIGLVDRIFTRVGASDDLARGRSTFMVEMTETAAILHNATRRSLVVLDEIGRGTSTFDGVSIAWAVAEHLHDVTGCRTLFATHYHELQDLARERPAVRNLTVAVREVGDRVVFLRKLVQGGASRSYGIEVAKLAGLPAEVLARAREILKNLEAMEVDEGGHPALARGRRRRAGPSAAQLGLFGGGAPADPAAEDVAKAIRAIDLDALRPLDALNLLAGWKKSLE
What is the function of this protein?
This protein is involved in the repair of mismatches in DNA.  It is possible that it carries out the mismatch recognition step.  This protein has a weak ATPase activity.
What are the official names of this protein?
DNA mismatch repair protein MutS.
What is the protein family that this protein belongs to?
Belongs to the DNA mismatch repair MutS family.
Protein: RL5_DESRM
Sequence: MARLKDKYLNEVQPNLMQKFGYKNIMQVPKLEKVIINIGLGEAVQNSKAVDAAVGDLMAITGQRPITTKAKKSIAAFKLRAGMTIGTKVTLRGERMYEFVDRLFNVALPRVRDFRGISDKSFDGRGNYTMGLKEQLIFPEIEYDKIDKVRGMDITFVTTAKTDEEARELLKLMGIPFVKVS
What is the function of this protein?
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.  In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement.  Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
What are the official names of this protein?
50S ribosomal protein L5.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL5 family.
Protein: RL3_PSEP1
Sequence: MTIGVIGRKCGMTRIFTEEGVSIPVTVIEIEPNRVTQFKTEETDGYRAVQVTVGERRASRVTAAQAGHFAKANVAAGRGVWEFRLEEGDFQAGDLIKAELFTAGQLVDVTGQSKGKGFAGTIKRWNFRGQDNTHGNSVSHRVPGSIGQCQTPGRVFKGKKMSGHMGAERVTVQSLEVVRVDAERNLLLIKGAVPGATGGDVVVRPAVKARG
What is the function of this protein?
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
What are the official names of this protein?
50S ribosomal protein L3.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL3 family.
Protein: GUN21_ORYSJ
Sequence: MVAAMTMCAAVAVLLVLTSTMAAAAGDGDGDGGGFDYKKALHSGLLYFEAQRSGHLPYNQRVRWRGHSGLADGLQQGVDLVGGYYDAGDNVKFGLPMAFTMTMLSWAAAEFWDEIAAAGERRHVLEAIKWGTDYLVKAHTAADELWAEVGDGDTDHYCWQRPEDMTTSRQAYKVDRDNPGSDVAGETAAALAAASIVFRRSKPRYSRLLLRHAEQLFDFGDRYRGKYDSSIGEVRAYYASVSGYGDELLWAALWLHRATGRRGYLDYAVAMADELGGVGWAVTEFSWDVKYAGLQILAAKVLMDGGDHPAAHAATLEQYRSKAEHYLCACLGKNAAAGDNVNRTAGGMLFVRRWNNMQYVTNAAFLLTVYSRYLRDSGGDTIRCSGGAMATGDELAAMARAQADYVLGDNPAGVSYMVGYGRRFPRRVHHRGASMVSHRADGRFVGCVQGYDRWFRRGGANPNVVAGAIVGGPDDRDRFRDSRDNYMQTEACTYNTAPMVGVFAHLHAQKMAARTANNNADRSMIKRVD
What are the official names of this protein?
Endoglucanase 21, Endo-1,4-beta glucanase 21, OsGLU9.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 9 (cellulase E) family.
What are the subcellular locations of this protein?
Secreted.
Protein: NTE1_USTMA
Sequence: MSQVPVASPASWSSVASAAAAAVSAATSASSSLAASVDEPAATTATAATASYADERNPLIALFDGLLRVVLASLNLIRILATFSTITVPSLVYAILHYSLTLQLNFPSLALLFLTSLISAFIWLRYRHLNKYERLREVPITRDEGFNLNPDVASPGGDNDRGSFHNYLDDFLQAIRIFGFLEKPVFHELARHLQTRRLVAGDSLSLDTDFSFYIVIDGHVQVYAPLPSATASAVGQDSVEDEDDSGYQLLNEVESGGTLSSLFTILSLFTEDVKLSFDDHDDPHLAPPHPAYPAMDRLNNSSAANHLGRGNNATAPTSPYSSAFNPPSQTAAQLQLNAAALRNVPAAISTEGAVERLGGSAAVRSTSKSSHARTASSGTASATVQDGDTSTIMDPLEQNDDGVTSSLYHAPDLQMPPAQAAAPFSHFAPSYHPSPAGTPISSLPGSTHSPYFRGRATSIHALHEAAGGPNTPGSILSAMSSSAHGHYHPQADYLPRQGAGTVARATVDTTLAVIPAEAFKRLTKKFPNAAAHIVQVILARLSRVTFHTAHKYLGLTKEVMRTEKSINDLACFPLPSEFYEKGGMDKLRHRFLPQPNSKRETTVDDDYFRDFQEWTSISQRSSTPVPGSKDDTKDAATSSPPKVRIASDLPSLTTSSKQSNQKPTSSRISAARTPWGHPDPPLKTPTARNMVGPGDLLSMASLSQDGWYTTGFDMHSAQPTPRAKPRSVSKLEPFHGPLPHPVDDSTDGTSPLSGASPIPIRKGSSTMYHQGEAIGTDRPFANIGLPHFDIKNEVMDCIAKSIGLAQAAHSPLAPSYQASPHINAQDSLLQRSVFKSAFGSLSMLDAAMAEEESSITGTNSSMAGHGHSGFHPSDFENEVEIKFFPAGSTLVKAGESRAGLFYVIDGFLDVLLPAEANELEEEDRLKPNMNHKSAKTDASSGSSRQNRPGSHRKDSSSASLRAGLLDERNLREADVSLPQRRGTEADRISSNGDGNSGSVHRPAMREGSSSSTSYGTPAGLRKKPTESAKVGNALDGTGGAGSSSRRKPSHVSSGSGATTMPRHPDATNSNMAFTAKQPVLHPSLHQQQPLRGKPSQQSSQRSKDGKRSIFTVGRGGIAGYLSSLLGTASYVDITAKTDVYVGFLPAHALERIMERRPIVLLTLCKRLLSLLPPLILHIDSSLDWQQVNAGQVIYREDDPSDSFFIVINGRLRAITEKTNGIEVHNEYGQGDSVGELDVITNSRRRTTLHAIRDSELAKMPSTLFNAISVRHPAITIQISRIIARRVRTELVRSKQEGAALGAPIPGLPDLGRNNLNLKTVAIVPVTRQVPVIDFAAKLQTAFDDTIGGRAIFLDQSSVMGVLGRHAFSRMGKLKLAGWLADLEQKYRLVVYVVDTPVSSAWSQTSIRQADCVLMVGFGDEPAMGEYERLLMSVKTTARKELVLLHPERSVPPGSTREWLKNRPWVHAHHHVEMPGLTGSHAGAAISTGGDPKAVKALRNLKQKLETSLQRYRKTMTPLSASGRPHHASDFARLARRLCGMSIGLVLGGGGARGCAHLGVIRALEERGIPIDMVGGTSIGSLVGGLYAREAEMVSTFGRAKRFAGRMASLWRFASDLTYPVVSYTTGHEFNRGVFKAIQETHIEDMWIPFFCNTTNITWSRMEVHTSGYAWRYIRGSMTLAGLIPPLVDEGNMLVDGGYVDNLPVTVMLAMGARSVFAVDVGSIDDTSPRAYGDTLSGWWVLLNRWNPWSDASKIPSIPDIQGRLTYVSSVKTLEEAKKVKGCFYMRMPVEEFGTLAFGRFDMIYEKGYKAAVELLDGWDAEGKLPSGTEREDFEDDWEDGDEYEEYEVYTDDESGVGGGVRKIRKKRRRTRRKAGISARRNSI
What is the function of this protein?
Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho).  Plays an important role in membrane lipid homeostasis.  Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity).
What are the official names of this protein?
Lysophospholipase NTE1, Intracellular phospholipase B, Neuropathy target esterase homolog.
What is the protein family that this protein belongs to?
Belongs to the NTE family.
What are the subcellular locations of this protein?
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein: ATPG_PICAN
Sequence: ATLREIETRLKSIKNIEKITNTMKVVASTRMGRAQRAMASSRAFREGDSDFFATAETSTPETAEKTLIIAVSSDKGLCGSIHSQIAKATRAKLQETPNADVVTIGDKIKAQMLRTHSSNVVLSFNGVGKEAPTFWEASLIADEIRKLGDYDKIEVMYNKFVSGVAFEPSVFPSFSPISIEESPKLSEFELEEDQAIPTSLSQISLTNAILNAMAEGYASEISARRNAMDNASKNAGEMINKYSILYNRTRQAVITNELVDIITGASSLD
What is the function of this protein?
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (PubMed:25759169).  F-type ATP synthases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk (PubMed:27791192).  During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).  Part of the complex F(1) domain and the central stalk which is part of the complex rotary element (By similarity).  The gamma/ATP3 subunit protrudes into the catalytic domain formed of alpha/ATP1(3)beta/ATP2(3) (By similarity).  Rotation of the central stalk against the surrounding alpha/ATP1(3)beta/ATP2(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta/ATP2 subunits (By similarity).
What are the official names of this protein?
ATP synthase subunit gamma, mitochondrial, F-ATPase gamma subunit.
What is the protein family that this protein belongs to?
Belongs to the ATPase gamma chain family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Note=The F-type ATP synthase complex is anchored in the mitochondrial inner membrane via the F(0) domain with the F(1) domain and the peripheral stalk extending into the mitochondrial matrix.
Protein: ATP6_CAMJ8
Sequence: MKDLFLFSSLLDASHTFSYFFHIGLVALIAVIVAMMATRSMQLVPRGMQNLGEAFLEGVLSMGRDTMGSEKGARKYLPLVATLGIIVFFSNIIGIIPGFHAPTASLNLTLSLAIIVFVYYHFEGIRAQGFVKYFAHFMGPIKLLAPLMFPIEIVSHLSRVVSLSFRLFGNIKGDDLFLMVILALVPYIAPLPAYVLLTFMAFLQAFIFMILTYVYLAGATVVEEGH
What is the function of this protein?
Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
What are the official names of this protein?
ATP synthase subunit a, ATP synthase F0 sector subunit a, F-ATPase subunit 6.
What is the protein family that this protein belongs to?
Belongs to the ATPase A chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: DNLJ_STRPQ
Sequence: MKKRIKELTDLLNRYRYDYYTKDAPSVSDSDYDKLYRELVTLEQSYPEYVLQDSPTQQVGGTILKGFEKYRHQYPLFSLQDAFSREELDAFDKRVKAEFPNATYLAELKIDGLSISLSYENGFLQVGATRGDGNIGENITENIKKIKDIPHQLSEPLTITVRGEAYMSRQSFKAINEGRQENGETEFANPRNAAAGTLRQLDTAVVAKRQLATFLYQEVSPTARNQQNEVLAELADLGFSVNPYYQLTSSMDEIWDFIKTIEAKRDQLAYDIDGVVIKVNSLAMQEELGFTVKAPRWAIAYKFPAEEKEAEILSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRIGDTVIVYKAGDIIPAVLNVVMSKRNQQEVMLIPKLCPSCGSELVHFEDEVALRCINPLCPSLIQRSLEHFASRDAMNITGLGPAIVEKLFLAGFVHDVADIYQLTKEDFMQLDGIKEKSADKLLAAIEASKSNSAEKLLFGLGIRHIGSKVSRLILEVYGDISALLTAKEEEIARIDGLGSTIAQSLTQYFEQKTAAILVDELKTAGVNMHYSGQKVNSDAALFGLTVVLTGKLNQLNRNEAKDKLEALGAKVTGSVSKKTDLVIAGSDAGSKLEKAKSLGIRIEDEDWLRQL
What is the function of this protein?
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction.  It is essential for DNA replication and repair of damaged DNA.
What are the official names of this protein?
DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)].
What is the protein family that this protein belongs to?
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Protein: GUN6_HUMIN
Sequence: QSGNPFSGRTLLVNSDYSSKLDQTRQAFLSRGDQTNAAKVKYVQEKVGTFYWISNIFLLRDIDVAIQNARAAKARGENPIVGLVLYNLPDRDCSAGESSGELKLSQNGLNRYKNEYVNPFAQKLKAASDVQFAVILEPDAIGNMVTGTSAFCRNARGPQQEAIGYAISQLQASHIHLYLDVANGGWLGWADKLEPTAQEVATILQKAGNNAKIRGFSSNVSNYNPYSTSNPPPYTSGSPSPDESRYATNIANAMRQRGLPTQFIIDQSRVALSGARSEWGQWCNVNPAGFGQPFTTNTNNPNVDAIVWVKPGGESDGQCGMGGAPAAGMWFDAYAQMLTQNAHDEIAR
What is the function of this protein?
Plays a central role in the recycling of plant biomass.  The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
What are the official names of this protein?
Endoglucanase-6B, Cellulase 6B, Endo-1,4-beta-glucanase 6B.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 6 (cellulase B) family.
Protein: SECE_RICCN
Sequence: MFKEYKIYKFFEQVKQETYKVVWPTRKELVASTLVVVVAVFIFSLICLVLDYSIHNIMQLLLNIGK
What is the function of this protein?
Essential subunit of the Sec protein translocation channel SecYEG.  Clamps together the 2 halves of SecY.  May contact the channel plug during translocation.
What are the official names of this protein?
Protein translocase subunit SecE.
What is the protein family that this protein belongs to?
Belongs to the SecE/SEC61-gamma family.
What are the subcellular locations of this protein?
Cell inner membrane; Single-pass membrane protein.
Protein: YO335_YEAST
Sequence: MEHSHWFRKMSSLHQEFVCFLFWPLT
What are the official names of this protein?
Putative uncharacterized protein YOR335W-A.
Protein: RL23_METPB
Sequence: MSADPRHYDVIVSPVITEKATNLTEQNKVVFRVAPKATKPQIKDAVEKLFDVKVTGVNTLTTKGKKKFFRGQRGQRSDVKKAIVTLAEGDTIDVTTGL
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: PGM1_HUMAN
Sequence: MVKIVTVKTQAYQDQKPGTSGLRKRVKVFQSSANYAENFIQSIISTVEPAQRQEATLVVGGDGRFYMKEAIQLIARIAAANGIGRLVIGQNGILSTPAVSCIIRKIKAIGGIILTASHNPGGPNGDFGIKFNISNGGPAPEAITDKIFQISKTIEEYAVCPDLKVDLGVLGKQQFDLENKFKPFTVEIVDSVEAYATMLRSIFDFSALKELLSGPNRLKIRIDAMHGVVGPYVKKILCEELGAPANSAVNCVPLEDFGGHHPDPNLTYAADLVETMKSGEHDFGAAFDGDGDRNMILGKHGFFVNPSDSVAVIAANIFSIPYFQQTGVRGFARSMPTSGALDRVASATKIALYETPTGWKFFGNLMDASKLSLCGEESFGTGSDHIREKDGLWAVLAWLSILATRKQSVEDILKDHWQKYGRNFFTRYDYEEVEAEGANKMMKDLEALMFDRSFVGKQFSANDKVYTVEKADNFEYSDPVDGSISRNQGLRLIFTDGSRIVFRLSGTGSAGATIRLYIDSYEKDVAKINQDPQVMLAPLISIALKVSQLQERTGRTAPTVIT
What is the function of this protein?
This enzyme participates in both the breakdown and synthesis of glucose.
What are the official names of this protein?
Phosphoglucomutase-1, PGM 1, Glucose phosphomutase 1.
What is the protein family that this protein belongs to?
Belongs to the phosphohexose mutase family.
Protein: TVA22_HUMAN
Sequence: MKRILGALLGLLSAQVCCVRGIQVEQSPPDLILQEGANSTLRCNFSDSVNNLQWFHQNPWGQLINLFYIPSGTKQNGRLSATTVATERYSLLYISSSQTTDSGVYFCAVE
What is the function of this protein?
V region of the variable domain of T cell receptor (TR) alpha chain that participates in the antigen recognition (PubMed:24600447).  Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes.  Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens (PubMed:25493333).  Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracellular activation of LCK that phosphorylates the ITAM motifs of CD3G, CD3D, CD3E and CD247 enabling the recruitment of ZAP70.  In turn ZAP70 phosphorylates LAT, which recruits numerous signaling molecules to form the LAT signalosome.  The LAT signalosome propagates signal branching to three major signaling pathways, the calcium, the mitogen-activated protein kinase (MAPK) kinase and the nuclear factor NF-kappa-B (NF-kB) pathways, leading to the mobilization of transcription factors that are critical for gene expression and essential for T cell growth and differentiation (PubMed:23524462).  The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement.  This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells.  Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity (PubMed:15040585).
What are the official names of this protein?
T cell receptor alpha variable 22.
What are the subcellular locations of this protein?
Cell membrane.
Protein: KGSDH_SACS2
Sequence: MKSYQGLADKWIKGSGEEYLDINPADKDHVLAKIRLYTKDDVKEAINKAVAKFDEWSRTPAPKRGSILLKAGELMEQEAQEFALLMTLEEGKTLKDSMFEVTRSYNLLKFYGALAFKISGKTLPSADPNTRIFTVKEPLGVVALITPWNFPLSIPVWKLAPALAAGNTAVIKPATKTPLMVAKLVEVLSKAGLPEGVVNLVVGKGSEVGDTIVSDDNIAAVSFTGSTEVGKRIYKLVGNKNRMTRIQLELGGKNALYVDKSADLTLAAELAVRGGFGLTGQSCTATSRLIINKDVYTQFKQRLLERVKKWRVGPGTEDVDMGPVVDEGQFKKDLEYIEYGKNVGAKLIYGGNIIPGKGYFLEPTIFEGVTSDMRLFKEEIFGPVLSVTEAKDLDEAIRLVNAVDYGHTAGIVASDIKAINEFVSRVEAGVIKVNKPTVGLELQAPFGGFKNSGATTWKEMGEDALEFYLKEKTVYEGW
What is the function of this protein?
2,5-dioxopentanoate dehydrogenase involved in the degradation of pentoses such as D-arabinose or D-xylose, a major component of hemicelluloses such as xylan.  Catalyzes the fifth reaction in the pentose utilization pathway through dehydratation of 2,5-dioxopentanoate into 2-oxoglutarate.  Shows also dehydrogenase activity toward glycolaldehyde and DL-glyceraldehyde.
What are the official names of this protein?
2,5-dioxopentanoate dehydrogenase, DopDH, Aldehyde dehydrogenase T, Alpha-ketoglutaric semialdehyde dehydrogenase AldhT.
What is the protein family that this protein belongs to?
Belongs to the aldehyde dehydrogenase family.
Protein: AZOR1_BACCZ
Sequence: MNKTLIINAHPKVDDTSSVSIKVFNHFLESYKEFIPNNETIEQINLYDDVVPMIDKTVLSAWEKQGNGQQLTDEEQKVTERMSEILQQFKSANTYVIVLPLHNFNIPSKLKDYMDNIMIARETFKYTETGSVGLLKDGRRMLVIQASGGIYTNDDWYTDVEYSHKYLKAMFNFLGIEDYQIVRAQGTAVLDPNEVLQNAYREVEEAASRLANK
What is the function of this protein?
Also exhibits azoreductase activity.  Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
What are the official names of this protein?
FMN-dependent NADH:quinone oxidoreductase 1, Azo-dye reductase 1, FMN-dependent NADH-azo compound oxidoreductase 1, FMN-dependent NADH-azoreductase 1.
What is the protein family that this protein belongs to?
Belongs to the azoreductase type 1 family.
Protein: SUCC_XANOM
Sequence: MNFHEYQSKQLLAEYGIPVPSGKVAATPDEAVDVATSLGKGPWMVKAQIHAGGRGKAGGVKFCKTTDDVKAAAAKMLGTKMSTYQTAGVELPINLVLVTTAGEIVKELYLSILVDRGTKTITYIASSEGGVEIEQVAAETPELIHALNVDFVEGVQGYHGRDFGFKLGLNAKQAGQFASIMVNLYKLFNEKDLALVEINPLAILDDGNLYALDGKFDSDDNAAFRQKQLVAMRDKTQEDETEVTASELDINYVTMDGNIGCMVNGAGLAMATMDVIKLNGGEPANFLDVGGGANKQRVIEAFKLILSSDKVEGIFVNIFGGIVRCDMIAEGIIAAVKEVGVKVPVVVRLEGTNVEEGKQLLRDSGMAIIPADNINDGAKKVVEAVKNAA
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.