PharMolix/UniProtQA huggingface dataset:
Protein: INX6_DROME
Sequence: MYAAVKPLSNYLRLKTVRIYDPIFTLHSKCTIVILLTCTFLLSAKQYFGEPILCLSSERQADYVQSYCWTMGTYILPAEVDRDGGSSWEYALYAPTSTAAETFNVSSLRALVAQNEQYARFISIAEGVGPETRGVTKRMYLRYYQWVFMILLFQSLLFYFPSFLWKVWEGQRMEQLCCEVGDALIVEATYRTRLQMLTRYFRAQFAPIHWCYSIKYAFCELLNVFISILNFWLMDVVFNGFWYKYIHALAAIPVYDWNLWNLMTSRVFPKVAKCEMFVYGPSGTPNIMDILCVLPLNILNEKIFAVLYVWFLFIALLAIMNILYRLLVICCPELRLQLLRTHLNGMPKSHVREVLASAGYGDWFVLMCVSINVNPTLFRELLEQLYAKLNQARCTEPVFAEQPCQQVPQLAQVPQLFSHAKLDRCPSRNCSLLIDPTADRHSICTESSHRVTAMPTAPTLNLMAPNDEIISMDRFFHESHA
What is the function of this protein?
Structural components of the gap junctions.
What are the official names of this protein?
Innexin inx6, Innexin-6, Gap junction protein prp6, Pas-related protein 6.
What is the protein family that this protein belongs to?
Belongs to the pannexin family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
Protein: MED10_DICDI
Sequence: MEQQQPQQQNDGQQQQQQQQQHQQQQQQQQQQQQQQQQSEQERIYNKKQEHLPLLQTVEELVEELRRSLIVVEEFQTPSQQLLFDKLNKIINLYEKIESNRHIVNDVEIPLEIFRVIDQSKNPDLYVKETLQNCLSANEKTKGKIESIKNFKKELESHISESFASEYAEYKLLTQKKETQEQQNDDQIKVDDSNNNNNNNNNNNYNNNNNNNNNNINNN
What is the function of this protein?
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes.  Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.  Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).
What are the official names of this protein?
Putative mediator of RNA polymerase II transcription subunit 10, Putative mediator complex subunit 10.
What is the protein family that this protein belongs to?
Belongs to the Mediator complex subunit 10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: FTHS_BACC1
Sequence: MTTTTTVKSDIEIAQEASMKKIQEIAADLNILEDELEPYGHYKGKLSLDIFKRLQNEKDGKVVLVTAINPTPAGEGKSTVTVGLGQAFNKIGKKTVIALREPSLGPTMGLKGGAAGGGFSQVVPMEDINLHFTGDIHAITTANNALAAFIDNHIQQGNTLGIDTRKIVWKRCVDLNDRALRNVVIGLGGPVQGVPREDGFDITVASEIMAVFCLATDIQDLKARLSRIVVAYNFANQPVTVKDLGVEGALTLLLKDALKPNLVQTLENTPAIIHGGPFANIAHGCNSVIATTMAAKLGDYVITEAGFGADLGAEKFLDIKARAAGIKPEAVVIVATIRALKMHGGVAKDQLKEENVDALAKGMENLQKHVETIQSFGVPFVIAINKFITDTDAEVAYLQEWCNERGYAVSLTEVWEKGGQGGVDLAEKVLKEIEKGENNYAPLYELELPLEEKIRTIAQKVYGAKDIEFAPKARKQLAQYEGEGWSNLPVCMAKTQYSLSDDATKLGRPSDFIVTIRELKPSIGAGFIVALTGTMLTMPGLPKQPAALQMDVNEDGKAVGLF
What are the official names of this protein?
Formate--tetrahydrofolate ligase, Formyltetrahydrofolate synthetase, FHS, FTHFS.
What is the protein family that this protein belongs to?
Belongs to the formate--tetrahydrofolate ligase family.
Protein: DYR21_ECOLX
Sequence: MERSSNEVSNPVAGNFVFPSNATFGMGDRVRKKSGAAWQGQIVGWYCTNLTPEGYAVESEAHPGSVQIYPVAALERIN
What is the function of this protein?
Key enzyme in folate metabolism.  Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
What are the official names of this protein?
Dihydrofolate reductase type 2, Dihydrofolate reductase type II.
Protein: VSP1_BOTAN
Sequence: VIGGDECNINEHPFLVALYYSTFFCGMTLINQEWVLTAAHESEKFPKEKYFIFCPNNKDIMLIRLDKPVSNSEHIAPLSLPSSPPSVGSVCRKPALYTKVFDYLLWIQSIIAGNTATCP
What is the function of this protein?
Thrombin-like snake venom serine protease, with high clotting activity in vitro.  Has also fibrinogenolytic ability, showing a fast degradation of fibrinogen Aalpha chain (FGA), a slow degradation of Bbeta chain (FGB) and no degradation of gamma chain.  Also causes platelet aggregation in platelet rich plasma (PRP) and washed platelet suspension.
What are the official names of this protein?
Thrombin-like enzyme TLBan, SVTLE TLBan, Fibrinogen-clotting enzyme, Snake venom serine protease, SVSP.
What is the protein family that this protein belongs to?
Belongs to the peptidase S1 family. Snake venom subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: DMS4_PITNO
Sequence: GLWSTIKQKGKEAAIAAAKAAGKAALNAASEAL
What is the function of this protein?
Has antiparasitic activity against trypomastigote form of T. cruzi (IC(50)=0. 25 uM) in vitro but not against L. infantum (PubMed:24113627).  Probably acts by permeabilizing cell membranes (PubMed:24113627).  In vitro, shows no cytotoxicity against macrophages (PubMed:24113627).  Has antibacterial activity (By similarity).
What are the official names of this protein?
Dermaseptin-4.
What is the protein family that this protein belongs to?
Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily.
What are the subcellular locations of this protein?
Secreted.
Protein: PSD_ANAMM
Sequence: MSFPSIHRHGYPFICLAFLCSCIGFALSSSLGVIFAMITALCAYFFRDPIRVIPLNDALVASPADGVVTSIVEVESPLNDGKTVTRISIFLSLFDVHVNRVPVSGVVKSVEHRPGSFSSAGSGGAVNENERVRAVIESSVGGHCIVVEQIAGVLARRIVCDLESGKAAKLGSRMGIIRFGSRMNIYIPAGMPVSVAEGHTVVGGETIIASLDADMATVHKDLTFDKV
What is the function of this protein?
Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
What are the official names of this protein?
Phosphatidylserine decarboxylase proenzyme.
What is the protein family that this protein belongs to?
Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
What are the subcellular locations of this protein?
Cell membrane; Peripheral membrane protein.
Protein: NU2C2_MANES
Sequence: MIWHVQNENFILDSTRIFMKAFHLLLFDGSFIFPECILIFGLILLLMIDSTSDQKDIPWLYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFVLTATLGGMFLCGANDLITIFVAPECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHAFSWLYGSSGGEIELQEIVNGLINTQMYNSPGISIALIFITVGIGFKLSLAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMIVGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVLFGLRTGTDNIRDYAGLYTKDPFLALSLALCLLSLGGLPPLAGFFGKLHLFWCGWQAGLYFLVLIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRSPLRSNNSIELSMIVCVIASTIPGISMNPIVEIAQDTLF
What is the function of this protein?
NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain.  The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone.  Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient.
What are the official names of this protein?
NAD(P)H-quinone oxidoreductase subunit 2 B, chloroplastic, NAD(P)H dehydrogenase, subunit 2 B, NADH-plastoquinone oxidoreductase subunit 2 B.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: EXUT_BACSU
Sequence: MFSKDKLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGGVASDRYGAKLTLFVAMVVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNWFPPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFSWKVSFVLIMIIGLIWAVLWFKFVKEKPQETIKEAPAIKAETSPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFPSYLVDERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSRKVVLVTCLFSSAVLIGFAGLVATTAGAVTLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHFLANTAGIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAVIRFVRPIIGKPAGTEAENPVSY
What is the function of this protein?
Transport of aldohexuronates such as D-glucuronate and D-galacturonate.
What are the official names of this protein?
Hexuronate transporter, Aldohexuronate transport system.
What is the protein family that this protein belongs to?
Belongs to the major facilitator superfamily. Phthalate permease family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: ICMF_PARXL
Sequence: MTDLSTPQRAGSHKLPAGRRLRFVTAAALFDGHDASINIMRRILQASGVEVIHLGHNRSVDEVATAALHEDADGVAVSSYQGGHNEYFRYLVDLLRARGGERIKVFGGGGGVIVPEEIAGLERYGVEKIYSPQDGQRLGLQGMIDDMIARCAEGARAAAATGESQVGAWAAEFSEHGLPRFDSRDDVGVDRQGAVARNPSSEASRVAAAGRGDHLDRGVRAASTADTADTANTANTANTANTGSVADAADAADAADAADAADAASTASTASTASTASTASTAGIPDPASLVFRRLAQLISAFETAAIDVNTRDKLSALAEVTAIPLLGITGTGGAGKSSLTDELIRRFRLDYGDALTIAVLAIDPSRRKSGGALLGDRIRMNAIGDWGGGARVYMRSMATREASSEISDSLPDALMLCKAAGFDLIVVETSGIGQGNAAIVPFVDESLYVMTPEFGAASQLEKIDMLDFASFVAINKFDRKGARDALRDVAKQVQRNRADFAKSPEAMPVFGTIASRFNDDGVTALYRHVAEALRKHGLRSGGGRLAAPEDLRFSSGRNAIVPPARVRYLADIAQTIHAYRERADAQARLARERWQLIEARRMLVETGEAARSTVATSASPGASASSKANACTSTSSKANASPGANTTANSNASATSGTATPTDALNPTLSQLDTLITQRTASLGERERILLDTWPEIVAAYSGTEHIVRVRDREIRTALTVATLSGSEVRKVSLPKFVDHGEILRWLMLDNLPGYFPFTAGVFPFRRENEDPTRMFAGEGDPQRTNRRFKLLSEGMPAKRLSTAFDSVTLYGEEPHERPDIYGKVGNSGVSVATLDDMKTLYDGFDLCAPETSVSMTINGPAPTILAMFFNVAIDQQIARTTQRQGRPLTEDELAATRRTALENVRGTVQADILKEDQGQNTCIFSTEFSLKVMGDIQAYFVEHGVRNFYSVSISGYHIAEAGANPISQLAYTLANGFTYVEAYLARGMSIDDFAPNLSFFFSNGMDPEYTVLGRVARRIWAVAMRERYGANERSQKLKYHVQTSGRSLHAQEIDFNDIRTTLQALIAIYDNCNSLHTNAFDEAITTPTEESVRRAVAIQLIINREWGLAKNQNPNQGSFVIEELTDLVEEAVLAEFDRLTERGGVLGAMETGYQRGRIQDESMLYEHRKHDGSYPIVGVNTFLSAHPHEAPQPIALARSTDDEKQSQLQRLRAFQAQHRDAAPAALERLKRAVIDDENVFAVLMDVVRVCSLGQITHALFEVGGQYRRNM
What is the function of this protein?
Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry (PubMed:19864421).  Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly (By similarity).  Does not exhibit methylmalonyl-CoA mutase (MCM) activity (PubMed:19864421).
What are the official names of this protein?
Fused isobutyryl-CoA mutase.
What is the protein family that this protein belongs to?
Belongs to the IcmF family.
Protein: CYSK_STAAS
Sequence: MAQKPVDNITQIIGGTPVVKLRNVVDDNAADVYVKLEYQNPGGSVKDRIALAMIEKAEREGKIKPGDTIVEPTSGNTGIGLAFVCAAKGYKAVFTMPETMSQERRNLLKAYGAELVLTPGSEAMKGAIKKAKELKEEHGYFEPQQFENPANPEVHELTTGPELLQQFEGKTIDAFLAGVGTGGTLSGVGKVLKKEYPNIEIVAIEPEASPVLSGGEPGPHKLQGLGAGFIPGTLNTEIYDSIIKVGNDTAMEMSRRVAKEEGILAGISSGAAIYAAIQKAKELGKGKTVVTVLPSNGERYLSTPLYSFDD
What are the official names of this protein?
Cysteine synthase, CSase, O-acetylserine (thiol)-lyase, OAS-TL, O-acetylserine sulfhydrylase.
What is the protein family that this protein belongs to?
Belongs to the cysteine synthase/cystathionine beta-synthase family.
Protein: MENC_MYCUA
Sequence: MIPGPATLPDLLDRLQVVALPMRVRFRGITTREVALIEGPSGWGEFGAFLEYQPPEAAAWLASAIDAAYGQPPPVRRGRIPINATVPAVPPAQVPELLARFPGARTAKVKVAEPGQTLASDVERVNAVRALVPTVRVDANGGWSVDQAAQAAVALTADGPLEYLEQPCATVGELAELRRRIEVPIAADEAIRKAEDPLAVVRAGAADVAVLKVAPLGGVWALLDIAAQIDIPVVISSALDSAVGIAAGLSAAAALPQLQHACGLGTGGLFVEDVAEPAIPVDGALAPQRVAPDPARLRALGAAPDRRQWWIDRIKACYPLLYRRSGD
What is the function of this protein?
Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB).
What are the official names of this protein?
o-succinylbenzoate synthase, OSB synthase, OSBS, 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase, o-succinylbenzoic acid synthase.
What is the protein family that this protein belongs to?
Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.
Protein: NU2M_DROME
Sequence: MFNNSSKILFITIMIIGTLITVTSNSWLGAWMGLEINLLSFIPLLSDNNNLMSTEASLKYFLTQVLASTVLLFSSILLMLKNNMNNEINESFTSMIIMSALLLKSGAAPFHFWFPNMMEGLTWMNALMLMTWQKIAPLMLISYLNIKYLLLISVILSVIIGAIGGLNQTSLRKLMAFSSINHLGWMLSSLMISESIWLIYFFFYSFLSFVLTFMFNIFKLFHLNQLFSWFVNSKILKFTLFMNFLSLGGLPPFLGFLPKWLVIQQLTLCNQYFMLTLMMMSTLITLFFYLRICYSAFMMNYFENNWIMKMNMNSINYNMYMIMTFFSIFGLFLISLFYFMF
What is the function of this protein?
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis.  Complex I functions in the transfer of electrons from NADH to the respiratory chain.  The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
What are the official names of this protein?
NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2.
What is the protein family that this protein belongs to?
Belongs to the complex I subunit 2 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: KDSB_PSET1
Sequence: MEFVVVIPARYASSRLPGKPLADICGKPMIQHVYEKACLSGASKVVIATDHQKVFDAVSTFTSDVLMTREDHQSGTERLAEVVDLLKLDNNTIVVNVQGDEPLLAPENVSQVATLLNESTAPMATLSVAIEEQEDVFNPNAVKVVSDINKNALYFSRASIPFDRSAMMGEQSTLDLTPFQRHVGIYAYRAGFIKQYIELSVSPLEQLESLEQLRVLYHGYNIKIEQAHITPQAGVDTPEDLAKVISYLQSKHA
What is the function of this protein?
Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
What are the official names of this protein?
3-deoxy-manno-octulosonate cytidylyltransferase, CMP-2-keto-3-deoxyoctulosonic acid synthase, CKS, CMP-KDO synthase.
What is the protein family that this protein belongs to?
Belongs to the KdsB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: FABZ_MOOTA
Sequence: MDWNAIQGILPHRYPFLLVDRVLEVEAGRRAVGQKNVSGNEWYFSGHFPGQPVMPGVLIMEALAQVGAVALLSLPEFQGRLALFGGMDRVRFRRQVVPGDVLRLETEIIKLKGRVGKGYGRAFVGEELAAEGELLFAVGEKIE
What is the function of this protein?
Involved in unsaturated fatty acids biosynthesis.  Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
What are the official names of this protein?
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ, (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase, (3R)-hydroxymyristoyl-ACP dehydrase, Beta-hydroxyacyl-ACP dehydratase.
What is the protein family that this protein belongs to?
Belongs to the thioester dehydratase family. FabZ subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RS14_RENSM
Sequence: MAKKSMIAKNDQRKVIVERYAEKRLALKKALVNPESTDEQREEARLGLQKLPRNASPIRLRNRDAIDGRPRGTLQKFGISRVRFRDMAHRGELPGIKKSSW
What is the function of this protein?
Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
What are the official names of this protein?
30S ribosomal protein S14.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS14 family.
Protein: SYFA_PERMH
Sequence: MGLKEDLKALEEEAKKLIEEASDIGKLNDIRVNYLGKKGKIKSILKTLGKLSPEERKEIGQLANRIKDELEEALKEKTELLKKKALEEELRKNRIDITLPPQWIESGSSHPVISTLIEISQIFISMGFSVAEGPEVEKEKYNFDMLNIPPDHPARDMQDTFFLNNGDILRTHTSPVQIRTMLKHKPPIAVIAPGRVYRKDADPTHSPMFHQIEGLLVDRDVTFRDLKGILKIFLESVFGKDTKIRFRPSYFPFTEPSAEVDIGCTVCGGKGCRVCKGTGWLEILGCGMVDPEVFKAVGIDPEEYTGFAFGLGIERIAMLKYRITDIRLLFTGDMRFNQQFKGIR
What are the official names of this protein?
Phenylalanine--tRNA ligase alpha subunit, Phenylalanyl-tRNA synthetase alpha subunit, PheRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: DNAK_STAAR
Sequence: MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
What is the function of this protein?
Acts as a chaperone.
What are the official names of this protein?
Chaperone protein DnaK, HSP70, Heat shock 70 kDa protein, Heat shock protein 70.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 70 family.
Protein: RL23_HELPY
Sequence: MADIMDIKSILYTEKSLGLQEKGVLVVQTAQNVTKNQLKEVFKTYFGFEPLKINSLKQEGKVKRFRGKLGQRKSFKKFYVKVPEGASIAALGA
What is the function of this protein?
One of the early assembly proteins it binds 23S rRNA.  One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.  Forms the main docking site for trigger factor binding to the ribosome.
What are the official names of this protein?
50S ribosomal protein L23.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL23 family.
Protein: G6PI_ASHGO
Sequence: MATTNTFSDFKLASELPAWAKLQELYEKKGKTLSLKEAFATDEQRFQKYSRTFSNHDGSKILFDFSKNLVDDEILGALAQLAREANVTQLRDQMFNGEHINSTEDRAVYHVALRNRANKPMYVDGKNVAPEVDAVLQHMKEFSEQVRSGAWKGYTGKSIKDVVNIGIGGSDLGPVMVTEALKHYAGPLKVHFVSNIDGTHLAETLKEVDPETTLFLVASKTFTTAETITNATSAKNWFLSKTGNNPAHISKHFAALSTNETEVAKFGIDTKNMFGFESWVGGRYSVWSAIGLSVALYIGFDQFEDFLKGAEAVDKHFTSTPIEDNIPLLGGLLSVWYNNFFDAQTHLVVPFDQYLHRFPAYLQQLSMESNGKSVTRGNVFANYSTGSILFGEPATNAQHSFFQLVHQGTKVIPSDFILAAQSHNPIENNLHQKMLASNFFAQAEALMVGKDEAQVKAEGATGGLVPHKVFSGNRPTTSILVQKITPANLGALIAYYEHVTFTEGAIWNINSFDQWGVELGKVLAKVIGKDLDTTGETTSHDASTNGLINQFKAWL
What is the function of this protein?
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.
What are the official names of this protein?
Glucose-6-phosphate isomerase, GPI, Phosphoglucose isomerase, PGI, Phosphohexose isomerase, PHI.
What is the protein family that this protein belongs to?
Belongs to the GPI family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: CYB_CHISR
Sequence: MPHQQILMLFGLLPVATNISTWWNFGSMLLACLTLQLLTGFFLAVHYTANINLAFSSIIHITRDVPYGWMMQNLHAIGASMFFICIYIHIARGLYYGSYLNKETWLSGTTLLIMLMATAFFGYVLPWGQMSFWAATVITNLLTAIPYLGSTMTTWLWGGFAINDPTLTRFFALHFILPFGIISLSSLHILLLHEEGSSNPLGTNSDIDKIPFHPYQTYKDMLMLTIMTIMLLTIVSFFPDIFNDPDNFSKANPLVTPQHIKPEWYFLFAYGILRSIPNKLGGALALTMSIMILLTMPFTHTSKLRSMMFRPLMQLTFWTFTATFLVISWTATKPVEPPFTTISQVAALMYFLFFISNPIMGWLENKIMKL
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: URE1_HALWD
Sequence: MSRKLSREAYTDLFGATEGDRLRLGDTNLLAKIEKDHGTYGDEAVFGGGKTMRDGMGMQSGTTQAEGALDWVFSNAVIIDPILGIQKGDIGVRDGKIAGIGKAGNPDTMDGVDDELVIGPSTDTAPADGLIATPGGLDIHIHFNSKELFEHALASGVTTMFGGGYGGGATTCTTGPENIKRFLQAAEEYPVNVGFYAKGNSSGPDPIIEQIEAGACGLKLHEDWGSTPDVIDTALTVADEEDVQVCIHTDTLNESGFLEDTFEAIDGRTIHTFHIEGAGGGHAPDVLELIGYDHMLPSSTNPSMPYTVNTFDEHLDMVMVCHHLNPDVPEDVAFAESRIRSETIAAEDVLHDMGAISMMTSDSQAMGRMAEVITRTWQTAHKMKSQRGALPADRGTDADNARIKRYVAKYTINPAKVAGINEYVGSLEPGKMADIVLWEPEFYGIKPKYVIKGGFPVHSEMGEANGSLMTCEPVMQRSRMGAVGKAKHAISTTFVSKAAYENDIGDQIGLESRVRPVEGTRDVGKNDMRHNEYAPENIDIDPQTFEVAVDGEHVTCEPAEELPLAKRYSL
What are the official names of this protein?
Urease subunit alpha, Urea amidohydrolase subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: SPAQ_SALEN
Sequence: MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLSGWYGEVLLSYGRQVIFLALAKG
What is the function of this protein?
Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells.
What are the official names of this protein?
Surface presentation of antigens protein SpaQ.
What is the protein family that this protein belongs to?
Belongs to the FliQ/MopD/SpaQ family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: U6VN_CONVE
Sequence: EDCIAVGQLCVFWNIGRPCCSGLCVFACTVKLP
What is the function of this protein?
Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav) (By similarity).  Has strong insecticidal properties at a dose of only 100 pmol/g of body weight (when injected into the haemocoel of the wax moth G.  mellonella larvae).  Provoques tremor and uncontrolled movements in insect larvae, that are typical symptoms caused by neurotoxins (PubMed:22728460).  On fish G. niger, intraperitoneal injection of the toxin causes full extension of the fins, change in posture, breathing difficulties (at 30 and 100 pmol/g body weight) and death (at 100 pmol/g body weight) (PubMed:22728460).
What are the official names of this protein?
Omega-conotoxin-like Vn2, Conotoxin Vn2, Conotoxin-Vn, Vn6A.
What are the subcellular locations of this protein?
Secreted.
Protein: OCP1_CALMC
Sequence: GFGD
What is the function of this protein?
Cardioactive; has both positive chronotropic and inotropic effects on the heart.  Ocp-2 is a 1000 time less active than Ocp-1.
What are the official names of this protein?
Cardioactive peptide Ocp-1/Ocp-2.
What are the subcellular locations of this protein?
Secreted.
Protein: IFNA4_HUMAN
Sequence: MALSFSLLMAVLVLSYKSICSLGCDLPQTHSLGNRRALILLAQMGRISHFSCLKDRHDFGFPEEEFDGHQFQKAQAISVLHEMIQQTFNLFSTEDSSAAWEQSLLEKFSTELYQQLNDLEACVIQEVGVEETPLMNEDSILAVRKYFQRITLYLTEKKYSPCAWEVVRAEIMRSLSFSTNLQKRLRRKD
What is the function of this protein?
Produced by macrophages, IFN-alpha have antiviral activities.  Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
What are the official names of this protein?
Interferon alpha-4, IFN-alpha-4, Interferon alpha-4B, Interferon alpha-76, Interferon alpha-M1.
What is the protein family that this protein belongs to?
Belongs to the alpha/beta interferon family.
What are the subcellular locations of this protein?
Secreted.
Protein: NUOB1_AZOSB
Sequence: MSIEGVFREGFVTTSLDAVINWTRTGSLWPMTFGLACCAVEMIHAGCSRYDLDRFGVVFRPSPRQSDLMIVAGTLCNKMAPALRKVYDQMAEPRWVISMGSCANGGGYYHYSYSVVRGCDRIVPVDVYVPGCPPTAEALLYGIIQLQNKIKRTNTIAR
What is the function of this protein?
NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.  Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity).
What are the official names of this protein?
NADH-quinone oxidoreductase subunit B 1, NADH dehydrogenase I subunit B 1, NDH-1 subunit B 1.
What is the protein family that this protein belongs to?
Belongs to the complex I 20 kDa subunit family.
What are the subcellular locations of this protein?
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side.
Protein: YNJ6_CAEEL
Sequence: MEGKLSMDSQILEEVIRSGNIPCHGRTGMLCAGGGLLPPALLDESRVPKFYLDALVASGGTSSTALPNTGLVYNLMGTSGLPKDVLSHIWSAVNRAKPGQLTRPEFFSLLALIALAQKGESLAALCAMDSLPIPYLNPVQAFPTASNPAPTTNTSSSFVPFGKIKPSAFIPTSLLPRRSMRKKKESDSKEVSAHNSPAKGAAHDLAGLDFGSDISSMKEEIKDINETPTQSCWRETVHAIYIVVEEANQLFKDSKKEVIQEISETEKGSAYFKSLSKAFDTLERVCKSAGVQLSVQSTKEAEYCRNLRRKWETFMDTTPEQNVEMTDDRKCAICCQPVQNPIDYGGQCFDVTCANLWVNGVSSTLPSLHLK
What are the official names of this protein?
Uncharacterized protein R10E11.6.
Protein: RL21_CAMJD
Sequence: MYAIIKHSGKQYKVSVGDDLKLDHFEAESKASIEVSEVLAINDKELKVGAPFVAGAKVVLEVINHGKDKKVVIYKKRRRKDSKLKRGFRRQFTRVVVKDIKA
What is the function of this protein?
This protein binds to 23S rRNA in the presence of protein L20.
What are the official names of this protein?
50S ribosomal protein L21.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL21 family.