PharMolix/UniProtQA huggingface dataset:
Protein: CD1D_RAT
Sequence: MLYLPCLLLWAFPQFWGQSEVQQNYTFGCLQISSFANRSWSRTDSVVWLGDLQTHRWSNDSDTISFTKPWSQGKFSNQQWEKLQHMFQVYRTSFTRDIKEIVKMMSPKEDYPIEVQLSAGCEMYPGNASESFLHVAFQGEYVVRFHGTSWQKVPEAPSWLDLPIKMLNADEGTRETVQILLNDTCPQFVRGLLEAGKPDLEKQEKPVAWLSRGPNPAHGHLQLVCHVSGFHPKPVWVMWMRGDQEQGGTHRGDILPNADETWYLQATLDVEAGDEAGLACRVKHSSLEGQDIILYWGGRQVSPVLIFLIVGVLVLVVCAVAYYIIRKRRRSYQDIM
What is the function of this protein?
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
What are the official names of this protein?
Antigen-presenting glycoprotein CD1d.
What are the subcellular locations of this protein?
Cell membrane; Single-pass type I membrane protein. Basolateral cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Protein: SPEA_DEIRA
Sequence: MCPARLRTPRTASLPTHRRSAMTTANPLNTSFTSADAAELYQVPNWSGGWFRVSDKGLMEATPAPGLHASLRAIVDEIVDRGESLPVILRFPQVLAGRVKHLNEAFQAAINEYNYSGHYQGVFPIKVNQRRAVVETVAAAGYDYAHGLEAGSKAELALCLAQKMHPDALLCCNGFKDDGFIKLALWGRTLGKNVVITIEKFTELDRILKQAKALGVKPAVGVRFKLHARGSGQWEESGGDQAKFGLNAYELLRVVERLKEENMLDSLVMLHTHIGSQITDIRRVKVAVREAAQTYAGLIAAGADLKYLNVGGGLGVDYDGSKTTFYASMNYTVKEYAADIVYTVQEVCKAREVPEPVIVSESGRALTAHHAVLILPVVDVTGPTRNLEDQELTVPGEDSHQIVRDMYETLENISMRNYRESYNDAVGDKQTLHNLFDLGYVTLEDRARGEALFNAILRKIAKLIQGEKYVPDELEDLQKVLADKFICNFSLFQSLPDNWAIGALFPIVPLDRLNEQPTRQATLVDITCDSDGKVEKFIDLRDVKATLPLHEPGDRPYYLGAFLMGAYQDVLGSAHNLFGKVSEAHVTVRPGGRFNIDLFVRGQKARRMIESMGYEEPMLRDAIEDQADAAIGRGTLTQEQEHELLEDYGEELLGYTYLEYES
What is the function of this protein?
Catalyzes the biosynthesis of agmatine from arginine.
What are the official names of this protein?
Biosynthetic arginine decarboxylase, ADC.
What is the protein family that this protein belongs to?
Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.
Protein: YPT1_ECOLX
Sequence: MKITDHKLSEGIALTFRVPEGNIKHPLIILCHGFCGIRNVLLPCFANAFTEAGFATITFDYRGFGESDGERGRLVPAMQTEDIISVINWAEKQECIDNQRIGLWGTSLGGGHVFSARAQDQRVKCIVSQLAFADGDVLVTGEMNESERASFLSTLNKMAEKKKNTGKEMFVGVTRVLSDNESKVFFEKVKGQYPEMDIKIPFLTVMETLQYKPAESAAKVQCPVLIVIAGQDSVNPPEQGKALYDAVASGTKELYEEADACHYDIYEGAFFERVAAVQTQWFKKHL
What are the official names of this protein?
Uncharacterized 31.7 kDa protein in traX-finO intergenic region.
What is the protein family that this protein belongs to?
To E.coli YcjY.
Protein: TSAD_CERS4
Sequence: MSRPLTFLGIESSCDDTAAAVVRAEGTRAEILSSVVDGQTALHAAFGGVVPEIAARAHAERLDLCVERALEEAGLGLRDLDGIAVTAGPGLIGGVLSGVMLAKGLAAGTGLPLVGVNHLAGHALTPRLTDGLAFPYLMLLVSGGHCQFLIARGAEEFSRLGGSIDDAPGEAFDKTAKLLGLPQPGGPSVEAEAAAGDPRRFAFPRPMLDRPGCDMSFSGLKTALLRARDGLVAEKGGLTRADRADLCAGFQAAVVEVLAEKTRRALAVYAAEGAAEPALAVAGGVAANGPIRAALTRVAEAAGVRFLAPPLRLCTDNAAMIAWAGIERFRAGGRDGMELSARPRWPLDRSAPALIGSGRKGAKA
What is the function of this protein?
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.  Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB.  TsaD likely plays a direct catalytic role in this reaction.
What are the official names of this protein?
tRNA N6-adenosine threonylcarbamoyltransferase, N6-L-threonylcarbamoyladenine synthase, t(6)A synthase, t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD, tRNA threonylcarbamoyladenosine biosynthesis protein TsaD.
What is the protein family that this protein belongs to?
Belongs to the KAE1 / TsaD family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PSBT_TOBAC
Sequence: MEALVYTFLLVSTLGIIFFAIFFREPPKVPTKKN
What is the function of this protein?
Seems to play a role in the dimerization of PSII.
What are the official names of this protein?
Photosystem II reaction center protein T, PSII-T.
What is the protein family that this protein belongs to?
Belongs to the PsbT family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: DEOC_SHEB2
Sequence: MTDLKKAAQRAIELMDLTTLNDDDTDQKVIDLCHKAKTAAGNTAAICIYPRFIPIARKTLDEIGAEDIQIATVTNFPHGNDDIAIAVLETRAAVAYGADEVDVVFPYRALMEGNETIGFELVKACKEACGEVLLKVIIESGVLADPALIRRASELSIDAGADFIKTSTGKVPVNATLEAAEIMLTVISEKNTQVGFKPAGGVRDAAQAAEFLGVAERILGADWVSPRTFRFGASSLLNSLLHTLELADAPKPTQGY
What is the function of this protein?
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
What are the official names of this protein?
Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase.
What is the protein family that this protein belongs to?
Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PURA_SALTY
Sequence: MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPSALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEYGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: NPC21_DICDI
Sequence: MKHSKNQIVYITFFIIILIVVKPIESVEWNDCSDPNDSFKIEKLEFSPEQPIAGQDLIISISGYLNKEITNGEAYLSITFDRIPIIKLKGNLCNGMGVTCPIQQGNYSTTTINQEIPENAPQGYYYVNFVLYDQDDLQITCIDVQMNITQS
What is the function of this protein?
Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
What are the official names of this protein?
Putative phosphatidylglycerol/phosphatidylinositol transfer protein 1, PG/PI-TP.
What is the protein family that this protein belongs to?
Belongs to the NPC2 family.
Protein: BORG5_MOUSE
Sequence: MPGPQGGTGAPTMSLGKLSPVGWVSSSHGKRRLTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGRSGNTHRSPRSFLARKLQQVRRVGVPPRRMASPAAPSPAPPPISPIIKNAISLPQLNQATYDSLVMGKLSFDSTPASSTDGHSGYGLESGFCTISRLPRVEKHSNRDRDRDPDHSQDREQSSFPSEPTPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAETPVPTANPPAPAANPAPTAKPPAHAITTLDAVTSLPASAVTSLPAPAAASSPSRGHFPNGVTSVLGPAAEAKPSPVGEGPQVPSNMTFDRHGASWGASRASWGASRASRHYTEMDARRELAGVLPQVHGSWESLNEDWSTPPASVRAPVPTSVQVNAFEFADAEEDDEVKV
What is the function of this protein?
Probably involved in the organization of the actin cytoskeleton.  Induced membrane extensions in fibroblasts (By similarity).
What are the official names of this protein?
Cdc42 effector protein 1, Binder of Rho GTPases 5.
What is the protein family that this protein belongs to?
Belongs to the BORG/CEP family.
What are the subcellular locations of this protein?
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Protein: TATA_DEHM1
Sequence: MPKIGPMEILIIVLLVVVVFGIGKLPQVGDAIGKGIRNFRKASSGEEEKEEVETKEETKTIEKSE
What is the function of this protein?
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.  TatA could form the protein-conducting channel of the Tat system.
What are the official names of this protein?
Sec-independent protein translocase protein TatA.
What is the protein family that this protein belongs to?
Belongs to the TatA/E family.
What are the subcellular locations of this protein?
Cell membrane; Single-pass membrane protein.
Protein: M2_I54A2
Sequence: MSLLTEVETPIRNEWGCRCNDSSDPLIIAASVVGILHLILWILDRLFFKCIYRLFKHGLKRGPSTEGVPESMREEYRKEQQSAVDADDSHFVNIELE
What is the function of this protein?
Forms a proton-selective ion channel that is necessary for the efficient release of the viral genome during virus entry.  After attaching to the cell surface, the virion enters the cell by endocytosis.  Acidification of the endosome triggers M2 ion channel activity.  The influx of protons into virion interior is believed to disrupt interactions between the viral ribonucleoprotein (RNP), matrix protein 1 (M1), and lipid bilayers, thereby freeing the viral genome from interaction with viral proteins and enabling RNA segments to migrate to the host cell nucleus, where influenza virus RNA transcription and replication occur.  Also plays a role in viral proteins secretory pathway.  Elevates the intravesicular pH of normally acidic compartments, such as trans-Golgi network, preventing newly formed hemagglutinin from premature switching to the fusion-active conformation.
What are the official names of this protein?
Matrix protein 2, Proton channel protein M2.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses matrix protein M2 family.
What are the subcellular locations of this protein?
Virion membrane. Host apical cell membrane; Single-pass type III membrane protein. Note=Abundantly expressed at the apical plasma membrane in infected polarized epithelial cells, in close proximity to budding and assembled virions. Minor component of virions (only 16-20 molecules/virion).
Protein: BAPT_TAXCU
Sequence: MKKTGSFAEFHVNMIERVMVRPCLPSPKTILPLSAIDNMARAFSNVLLVYAANMDRVSADPAKVIREALSKVLVYYYPFAGRLRNKENGELEVECTGQGVLFLEAMADSDLSVLTDLDNYNPSFQQLIFSLPQDTDIEDLHLLIVQVTRFTCGGFVVGANVYGSACDAKGFGQFLQSMAEMARGEVKPSIEPIWNRELVKLEHCMPFRMSHLQIIHAPVIEEKFVQTSLVINFEIINHIRRRIMEERKESLSSFEIVAALVWLAKIKAFQIPHSENVKLLFAMDLRRSFNPPLPHGYYGNAFGIACAMDNVHDLLSGSLLRTIMIIKKSKFSLHKELNSKTVMSSSVVDVNTKFEDVVSISDWRHSIYYEVDFGWGDAMNVSTMLQQQEHEKSLPTYFSFLQSTKNMPDGIKMLMFMPPSKLKKFKIEIEAMIKKYVTKVCPSKL
What is the function of this protein?
Acyltransferase involved in taxol biosynthesis (PubMed:12232048).  Catalyzes the selective 13-O-acylation of baccatin III with (3R)-3-amino-3-phenylpropanoyl-CoA as the acyl donor to form 3'-N-debenzoyl-2'-deoxytaxol (PubMed:12232048).
What are the official names of this protein?
Baccatin III:3-amino-3-phenylpropanoyltransferase.
What is the protein family that this protein belongs to?
Belongs to the plant acyltransferase family.
Protein: RL35_STAA1
Sequence: MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQLRKARLVSKSDMKRVKQLLAYKK
What are the official names of this protein?
50S ribosomal protein L35.
What is the protein family that this protein belongs to?
Belongs to the bacterial ribosomal protein bL35 family.
Protein: MAX_HUMAN
Sequence: MSDNDDIEVESDEEQPRFQSAADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQNALLEQQVRALEKARSSAQLQTNYPSSDNSLYTNAKGSTISAFDGGSDSSSESEPEEPQSRKKLRMEAS
What is the function of this protein?
Transcription regulator.  Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'.  The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor.  May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity.  Represses MYC transcriptional activity from E-box elements.
What are the official names of this protein?
Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X.
What is the protein family that this protein belongs to?
Belongs to the MAX family.
What are the subcellular locations of this protein?
Nucleus. Cell projection, dendrite.
Protein: HIS4_PELPD
Sequence: MLVIPAIDLKDGVCVRLEQGLMDRDTVFNDNPASQALEWQNQGAELLHIVDLDGAFAGTPRNKAAIEAIVKAISIPAQLGGGIRDLATIESYLSLGLSRVIIGTAAQRNPQLVKEACAKFPGRIVVGIDAKAGMVAVQGWAEVTGITAVDLARKFEDCGVAAIIYTDISRDGMLQGPNIEATRSLAEAVAIPVIASGGVSTLKDIENLMTIERSGVTGVITGKAIYTGAIRLHEAIALTGKDNQE
What are the official names of this protein?
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase, Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
What is the protein family that this protein belongs to?
Belongs to the HisA/HisF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ATPL_ECO57
Sequence: MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
What is the function of this protein?
Key component of the F(0) channel; it plays a direct role in translocation across the membrane.  A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
What are the official names of this protein?
ATP synthase subunit c, ATP synthase F(0) sector subunit c, F-type ATPase subunit c, F-ATPase subunit c, Lipid-binding protein.
What is the protein family that this protein belongs to?
Belongs to the ATPase C chain family.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: QUEE_PYRAE
Sequence: MSATPRVRVLEIFASLQGEGINLGRPAVFVRLAGCPIRCIYCDTKYSWDFNAGVEMGVEEIVAKALALSVVGHVVVTGGEPLIWQRRGLEELACALRALGSVEVETSGAYPPTPELDRCVDFYDVSPKLSNAGVKAPFSPFYASSPKAWFKFVVSNADDVEEVERFVVAYGIPRGRVFLMPMAESPEEHGEALRRIWDAAVRGGFRVTPRLHIMAWGNARGK
What is the function of this protein?
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
What are the official names of this protein?
7-carboxy-7-deazaguanine synthase, CDG synthase, Archaeosine biosynthesis protein QueE.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
Protein: GCSH_METPB
Sequence: MLRFTDEHEWLRLDGDVATVGITAHAAEQLGDLVFVELPKVGVKLTKGEAAAVVESVKAASDVYAPLSGEVTEVNEAALSDPASVGADPQGAGWLYRLKLDDVSAMDALMDEAAYADFAK
What is the function of this protein?
The glycine cleavage system catalyzes the degradation of glycine.  The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
What are the official names of this protein?
Glycine cleavage system H protein.
What is the protein family that this protein belongs to?
Belongs to the GcvH family.
Protein: AP3S_YEAST
Sequence: MIHAVLIFNKKCQPRLVKFYTPVDLPKQKLLLEQVYELISQRNSDFQSSFLVTPPSLLLSNENNNDEVNNEDIQIIYKNYATLYFTFIVDDQESELAILDLIQTFVESLDRCFTEVNELDLIFNWQTLESVLEEIVQGGMVIETNVNRIVASVDELNKAAESTDSKIGRLTSTGFGSALQAFAQGGFAQWATGQ
What is the function of this protein?
Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated.  The complex is associated with the Golgi region as well as more peripheral structures.  It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to the vacuole.  Required for the transport via the ALP pathway, which directs the transport of the cargo proteins PHO8 and VAM3 to the vacuole.
What are the official names of this protein?
AP-3 complex subunit sigma, AP-3 complex sigma3A subunit, Adaptor-related protein complex 3 subunit sigma, Clathrin-associated/assembly/adaptor protein, small 3, Sigma-adaptin 3A, Sigma3-adaptin.
What is the protein family that this protein belongs to?
Belongs to the adaptor complexes small subunit family.
What are the subcellular locations of this protein?
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein: VRP1_SCHPO
Sequence: MAPAPPPPPPAPAPAAAAPAPPLMTGDRSALLNSIQKGKKLKKATTNDRSAPVVGGGVVGERKSNTPKSFAAPPVPTGAPSLPTSSNNTQQAEERPSMPALGGLFAGGMPKLRHIGKSSASAAPPSAPAPPTPQSELRPPTSAPPRPSIPPPSPASAPPIPSKAPPIPSSLPPPAQPAAPVKSPPSAPSLPSAVPPMPPKVPPPPLSQAPVANTSSRPSSFAPPAGHAPNVTSESPKFPNRGPSIPSASVPPVPPSSYVLQQRPNRVDDHGRFHFKDDSYLPIPHPFLGVPKVYRGGSGTTVPLNLSSF
What is the function of this protein?
Involved in cytoskeletal organization and cellular growth.  May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins such as profilin or proteins possessing SH3 domains.  Plays a role in actin patch assembly by enhancing the ability of myo1 to stimulate actin polymerization by the Arp2/3 complex.
What are the official names of this protein?
Verprolin.
What is the protein family that this protein belongs to?
Belongs to the verprolin family.
Protein: POL5_DROME
Sequence: MITHRLVGKFFKPLGNDSDITFFVLPNLHSFDGIIGDDTLKDLKAIVDRKNNCLIITPGIKIPLLARASINVNPLLAAEHPDGTQEILNSLLGEFPRIFEPPLSGMSVETAVKAEIRTNTQDPIYAKSYPYPVNMRGEVERQIDELLQDGIIRPSNSPYNSPIWIVPKKPKPNGEKQYRMVVDFKRLNTVTIPDTYPIPDINATLASLGNAKYFTTLDLTSGFHQIHMKESDIPKTAFSTLNGKYEFLRLPFGLKNAPAIFQRMIDDILREHIGKVCYVYIDDIIVFSEDYDTHWKNLRLVLASLSKANLQVNLEKSHFLDTQVEFLGYIVTADGIKADPKKVRAISEMPPPTSVKELKRFLGMTSYYRKFIQDYAKVAKPLTNLTRGLYANIKSSQSSKVPITLDETALQSFNDLKSILCSSEILAFPCFTKPFHLTTDASNWAIGAVLSQDDQGRDRPIAYISRSLNKTEENYATIEKEMLAIIWSLDNLRAYLYGAGTIKVYTDHQPLTFALGNRNFNAKLKRWKARIEEYNCELIYKPGKSNVVADALSRIPPQLNQLSTDLDANPEDDMQSLATAHSALHDSSRLIPHVESPINVFKNQLIFDTTRSKYLCEHPFPGYTRHLIPLKDGSLADLTNSLQSCLRPVIINGVKIPEAHLQRFQSICLANFLLYKIRITQRLVADVSGAEEICEIIEKEHRRAHRGPTEIRLQLLEKYYFPRMSSTIRLQTSSCQCCKLYKYERHPNKPNLQPTPIPNYPCEILHIDIFALEKRLYLSCIDKFSKFAKLFHLQSKASVHLRETLVEALHYFTAPKVLVSDNERGLLCPTVLNYLRSLDIDLYYAPTQKSEVNGQVERFHSTFLEIYRCLKDELPTFKPVELVHIAVDRYNTSVHSVTNRKPADVFFDRSSRVNYQGLTDFRRQTLEDIKGLIEYKQIRGNMARNKNRDEPKSYGPGDEVFVANKQIKTKEKARFRCEKVQEDNKITVKTRSGKIFHKSDLRN
What are the official names of this protein?
Retrovirus-related Pol polyprotein from transposon opus.
Protein: RL16_ALISL
Sequence: MLQPKRTKFRKVMTGRNRGLAKGTEVSFGEFGLKAVGRGRLTARQIEAARRAMTRHVKRQGQIWIRVFPDKPITEKPLEVRQGKGKGNVEYWVAQIQPGKVMYEMNGVPEELAREAFRLAARKLPIKTTFVTKQVM
What is the function of this protein?
Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
What are the official names of this protein?
50S ribosomal protein L16.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL16 family.
Protein: YIHI_YERP3
Sequence: MKQPNKAPRANIAAPKGTATPKRRRKTRDELDAEARDRKRQKKHSGNRSGARTNVEGSNKKGHSQTQEKDPRVGSKVPVPLVIESQVKAKSMPKPVEKNVVKPRLTPEEELAKLENDERLDALLDRLDNDEVLNKEDQAYVDLTLDRIDALMEQLGIELGDDEDDVEREEKQEDILQLLKRGNPKDTF
What is the function of this protein?
A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function.  May play a role in ribosome biogenesis.
What are the official names of this protein?
Der GTPase-activating protein YihI.
What is the protein family that this protein belongs to?
Belongs to the YihI family.
Protein: VTS1_CANAL
Sequence: MEQSQGNIANSPPTSEIPQRPIILSPPPLDQNSLNQSFNNLPTSVPQGHANRQQSVGYNLQHEFETLTANLDLDLNSSTRNITQSAPPNQQQQQQSQLQATDSQLLTTTADLNTKPAHSVKPTLAAPAASRYGSHLGSDLLGKSTSSLLGDNNPVSPIQKFSSINTQLDSLLNNNISSAKSKTGTNSPFLSNAGLSNRPQSVNDFSNIFNRQDQQQQQQSQTFSSFTTQQQSQNQNQNQNQSNFYSDLIVFSNWIENLNPQDNLTMIDYLCSNLPLDILLTFKSKLDLHLQGGSAQNQQSQQSQLLPQFVMSPYSQYDQQLYNDMDKLNIQDDSFKSKHGNSSFRSNHLANLIDKVERPKSADPFVNNTKYGQYQQQSYNQHSYQQQHPLVDRAKSPTSHLYEKTNFLQLAAANSNNTGGNYNQYMPSLSSTSSSLGQANSNNTSTRDDMDLKLGALATINSRVALDSNRKHPHVATPGSTWNNQTHTHSHISPPHHNQMHSGVRNVSNFEESINRSLNSSSVPASMHKSNYSNSHGNNSNNNSGNTNINSNQNKGTHKKKINSPTSAVSMQQNSTSVNSTTSGNGGANANVNTTATTSSSSSSSMPIEVSSLELLNNIPAWLKLLRLHKYTECLKDVPWKELIELDNDQLESKGVAALGARRKLLKAFDVVKNNLPVV
What is the function of this protein?
RNA-binding protein involved in post-transcriptional regulation through transcript degradation.
What are the official names of this protein?
RNA-binding protein VTS1.
What is the protein family that this protein belongs to?
Belongs to the VTS1 family.
What are the subcellular locations of this protein?
Cytoplasm, cytosol. Cytoplasm, P-body.
Protein: MINC_SHIDS
Sequence: MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLKHAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGKEKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARLQLVENALTVQPLN
What is the function of this protein?
Cell division inhibitor that blocks the formation of polar Z ring septums.  Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.  Prevents FtsZ polymerization.
What are the official names of this protein?
Probable septum site-determining protein MinC.
What is the protein family that this protein belongs to?
Belongs to the MinC family.
Protein: PSBD_HORVU
Sequence: MTIALGRVPKEENDLFDTMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFALIGFMLRQFELARSVQLRPYNAISFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSAIGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL
What is the function of this protein?
Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.  The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors.  D2 is needed for assembly of a stable PSII complex.
What are the official names of this protein?
Photosystem II D2 protein, PSII D2 protein, Photosystem Q(A) protein.
What is the protein family that this protein belongs to?
Belongs to the reaction center PufL/M/PsbA/D family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Multi-pass membrane protein.
Protein: CH60_BRUMB
Sequence: MAAKDVKFGRTAREKMLRGVDILADAVKVTLGPKGRNVVIEKSFGAPRITKDGVSVAKEVELEDKFENMGAQMLREVASKTNDTAGDGTTTATVLGQAIVQEGAKAVAAGMNPMDLKRGIDLAVNEVVAELLKKAKKINTSEEVAQVGTISANGEAEIGKMIAEAMQKVGNEGVITVEEAKTAETELEVVEGMQFDRGYLSPYFVTNPEKMVADLEDAYILLHEKKLSNLQALLPVLEAVVQTSKPLLIIAEDVEGEALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGQVISEDLGIKLESVTLDMLGRAKKVSISKENTTIVDGAGQKAEIDARVGQIKQQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKEKKDRVDDALNATRAAVEEGIVAGGGTALLRASTKITAKGVNADQEAGINIVRRAIQAPARQITTNAGEEASVIVGKILENTSETFGYNTANGEYGDLISLGIVDPVKVVRTALQNAASVAGLLITTEAMIAELPKKDAAPAGMPGGMGGMGGMDF
What is the function of this protein?
Together with its co-chaperonin GroES, plays an essential role in assisting protein folding.  The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.
What are the official names of this protein?
Chaperonin GroEL, 60 kDa chaperonin, Chaperonin-60, Cpn60.
What is the protein family that this protein belongs to?
Belongs to the chaperonin (HSP60) family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PDCL3_DANRE
Sequence: MQDPNADTEWNDILRKKGILPPKETPVEEEEDEQLHLQSQSVVKTYEDMTLEELEENEDEFSEEDEHAMEMYRLKRLAEWKANQMKNVFGELKEISGQDYVQEVNKAGEGIWVVLHLYKQGIPLCSLINQHLAQLARKFPQSKFLKSISSTCIPNYPDRNLPTLFVYRDGEMKAQFIGPLVFGGMNLTCDELEWRLSESGAVKTDLEENPRKQIQDQLMTSIRCSANTHRDGEEDSDED
What is the function of this protein?
Acts as a chaperone for the angiogenic VEGF receptor KDR/VEGFR2, increasing its abundance by inhibiting its ubiquitination and degradation (PubMed:26059764).  Inhibits the folding activity of the chaperonin-containing T-complex (CCT) which leads to inhibition of cytoskeletal actin folding (By similarity).  Acts as a chaperone during heat shock alongside HSP90 and HSP40/70 chaperone complexes (By similarity).  Modulates the activation of caspases during apoptosis (By similarity).
What are the official names of this protein?
Phosducin-like protein 3, Viral IAP-associated factor 1 homolog.
What is the protein family that this protein belongs to?
Belongs to the phosducin family.
What are the subcellular locations of this protein?
Cytoplasm. Cytoplasm, perinuclear region. Endoplasmic reticulum.