PharMolix/UniProtQA huggingface dataset:
Protein: THO2_SCHPO
Sequence: MTSLPEKDQQGEVSVSENQKKLSEEWEPYIDKLVASNRTRDERVESIQELFQKCVIEEKLPVDIFFSIFSLAFERLEEKNTLASYVIDTLWLFDTEWIKNFHEGSHDKAEKRLVSIGKGLKEFLPEEWLLSRLDCKFLENINVVPNGDFLNRKIVRTNTSLLYRQKKFNLLREESEGFSHLMINFFDALTCLRNKSLNEDYLIVQVNKSIISTIGAFDLDPNKVLDLILLLFSENLLDSWRFFLSILRNSPWGPNKERKFWNQLPDREKETFLNNLSNANGIFNFDERFTNTKSIMSQVLGHNLQYMYKEDDENLESYFMMVALLIKYNFISIDNIWAHLSPSDEELGKELGKYKDKLDEQTFKAKGNALTMAAPLPDDEIEDGETMDGQKAEAVPEIKKAKPSQKLGLLKSLLSIGDLSSSLLILGRYPFLLRAYPELSNLYHKLLHISISSIYANYSPLKLLPNDVRERLKQPKFIPEDSRLREITLRPPKEKNLVFSLDPFADRFNKTESEVFYYFENYDEDIPILRNLTEFYNIAIPWLRLSGLALCHDPVIVTKLCRIGQKCVDNSSESRTLWLDIIRSLLLPLITLIDVNTGLSYELFELLSKFDSSTRYALYGEWSSTSMKKFPELKLQNSITEKETKGILRRLTKTNVKQFGRLLAKVCHSNPCTVFSIALNQIETYDNLVEVVVDSARFITALDFDALTFIILSSFSNEFKKRLKSDGTSIAHWLQGLASFCGRVFRRYSSLDCTSIVEYVIKQFKVNQMFDLVILKELLSQMTGLQPWTNLSDNQIQGAAGGPVLRQLSLSLIYENPDVVRKSSMRLFNTLQKNGLATQLLVLLSQKYSTCIYDVTDENSHLKLISSLQDECSDVLYLLMEFLNMVCSPKSYYKLIPSFEQLIQDFHIQPQVAFYLSRYKNLDHSLTGSNTEDAMDIDYENTSSPNTASNPVWSIDNSVITELLPKQIWDYFSPNFYLTFWKLSLYDVFVPLERYEFERSRAFDQIRQTDAANTFYSRHRHDRQKIMQLSNSLQNELKEHINSLESVRKVLQGDCVKWFIPNGVFPNGTRLEHARFNCARYLWTLCIAPRLKMSPHDALYCAKFVKLLHSLGTPNFSTMSFLEILFNSQLPSFIFSMTQREADNFGRFLYEVLYDITSWYRDKILYERECLANGALPGFRLYWSDEQNDPDLSAVLPYNKFVLLFSKWHKYLTSYFESCLLSTEYMHIYNSVIILEKILPCFPLIIESGSALKRAAERLKDEEKREDLKVLALGYFAKLSKKQPEWVSFNSFSGTVRPSNSEKLQRPQQLSVAATSAVDSKTASISEEQAKIDKQKVALNPSAPEFVPDSTPSDAVASETDNKNLVENKAVEKRVEARSSANERKQEERRRKTTPEGNRRALRTRTPTNEDIQRSDSKLREDQSRDRTPQSRSFTNENNDNLRSVSRHTRREPQQAQNLNARREHESQKSDRWRQNGNVNRNPRVSNNNSTNVSRERSSEANHRTSNDNKRDEVTEGKDKNKRQDISGESNSRQNNAISRAGRSNGSNRGNDSRDADGRRSTHYASNKRPRSSDSQSPSNLREEDERENSRRRARQDDRRDRDSRQQRDRPRDRTSRSAREEKRRKIQ
What is the function of this protein?
Component the THO subcomplex of the TREX complex, which operates in coupling transcription elongation to mRNA export.  The THO complex is recruited to transcribed genes and moves along the gene with the elongating polymerase during transcription.  THO is important for stabilizing nascent RNA in the RNA polymerase II elongation complex by preventing formation of DNA:RNA hybrids behind the elongating polymerase.
What are the official names of this protein?
THO complex subunit 2.
What is the protein family that this protein belongs to?
Belongs to the THOC2 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: MPAO_CLAUC
Sequence: MISPVSSILASIWDNSKLLLDHTSVLSIALIGVACAISIRSILYVRLACANYSILLLTHAQRLRLAYSTPLRHVPGPWYAKFTALGLRANDVAGNRWYYVQGLHKKYGSIVRIAPEEVAISDPKVVSKVHALGTEFRKRQQPGTPFNIFSISDPKAHRTRQRFYAKAFSDETLKASTEPAVRQLIKTAVASIKRDAALRKDHTADVYKWCMLFGSDVAFQVIYGNSNTEGLMATQKTTDEVIMGAYLQRMNAWAQFCFPVFLLGRWLSPLSPTLHNIFRVEEKYGDFWQEGQRQREIAARTVFVQNTKYSKNDGVFSVSDEVKLSDVDIAHDITTFLGAGGEPVGASLVFLIWQVLRMPDLQRELEAEVAGLTEPITDATTAQLPILNGVIYETLRLYGGGVTQMPRYAPIATELGGYVIPPGTAVTTHTGALHRNPAAWDDPEK
What is the function of this protein?
Methylphloroacetophenone oxidase; part of the gene cluster that mediates the biosynthesis of usnic acid, a dibenzofuran lichen product possessing a broad spectrum of biological activities (PubMed:26895859).  Two genes, mpas and mpao, comprise the usnic acid biosynthetic gene cluster with a single post-PKS enzyme, the methylphloracetophenone oxidase (mpao) (PubMed:26895859).  The methylphloroacetophenone synthase (mpas) is a non-reducing polyketide synthase that produces methylphloracetophenone from acetate via a methylated tetraketide intermediate (PubMed:26895859).  The methylphloroacetophenone oxidase then carries out the oxidative dimerization of methylphloracetophenone to usnic acid (PubMed:26895859).
What are the official names of this protein?
Methylphloroacetophenone oxidase, MPAO, Cytochrome P450 monooxygenase MPAO, Usnic acid biosynthesis protein MPAO.
What is the protein family that this protein belongs to?
Belongs to the cytochrome P450 family.
What are the subcellular locations of this protein?
Membrane; Single-pass membrane protein.
Protein: MURB_CHLMU
Sequence: MTNAFPFSVQESVPLNRFSTFRIGGPARYFKELVSVDEALKVFSFLHTSPIPYIIIGKGSNCLFHDQGFNGLVLYNNIQGQTFLSDTQIKVLSGVSFSLLGRQLSSKGFSGLEFAVGIPGTVGGAVFMNAGTALANTASSLVSVEIIDHAGNLLSLSREELLFSYRTSPFQKKTAFIVSATFQLTRDSQAAQRAKALIEERILKQPYEYPSVGCIFRNPEGVSAGALIDQAGLKGLTIGGGQISQKHGNFIINTGNASAADVLELIETIQKTLKQQGIALEKEVRIIPFQPNLGVS
What is the function of this protein?
Cell wall formation.
What are the official names of this protein?
UDP-N-acetylenolpyruvoylglucosamine reductase, UDP-N-acetylmuramate dehydrogenase.
What is the protein family that this protein belongs to?
Belongs to the MurB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVB_CAUVC
Sequence: MTRVISGEPQHGDLAPADRALRPQTLAEFVGQEQAKGNLRVFIEAAKGRGEALDHVLLFGPPGLGKTTLAQIVARELGVNFRATSGPVLNKPGDLAAILTNLEANDVLFIDEIHRLSSNVEEILYPAMEDHVLDLVIGEGPSARSIRIDLAPFTLVAATTRAGMLATPLRDRFGIPIRLEFYTPAELRHVLQHAARKMGAPLTDDGADEIAKRARGTPRVAGRLLRRVRDFATADGADRIDRKAAAMALARLEVDESGLDSLDRRYLRAMIENYGGGPVGVETIAYAIAEARDAVEDVIEPYLMQQGFIQRTPRGRMACGKAYLHLGLTPPAAPPGQAQGALFDEG
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time.  Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange.  Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration.  The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration.  Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvB.
What is the protein family that this protein belongs to?
Belongs to the RuvB family.
Protein: YL720_MIMIV
Sequence: MVEAPRIRITYEKIRHTKNHRIVSISGPSYKRMNVDLIDYIIRKWWFAGKYIYLMLISSNKPTYVIRTHMMMHGRILVGNQDSPTKRAFMIIQLDNDIVLRWYRSQITLLDPNCLAEIKTNYTICTTRQAIMDSIKLMKYDLSNNRFDYNLFQSHLKNGINIHSSEIITDFLLDQEYFPGVGNILQQEALYDCKILPLKKVQDIDEPMFDCLCNSLKKIIDLLYESYKFRESGKEFGPILRIYRKSLCPLGHKTIRKKIGLRNRMTTWCPVCQL
What are the official names of this protein?
Endonuclease 8-like L720, Endonuclease VIII-like L720.
What is the protein family that this protein belongs to?
Belongs to the FPG family.
Protein: HMGA2_MOUSE
Sequence: MSARGEGAGQPSTSAQGQPAAPVPQKRGRGRPRKQQQEPTCEPSPKRPRGRPKGSKNKSPSKAAQKKAETIGEKRPRGRPRKWPQQVVQKKPAQETEETSSQESAEED
What is the function of this protein?
Functions as a transcriptional regulator.  Functions in cell cycle regulation through CCNA2.  Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.  Plays a role in postnatal myogenesis, is involved in satellite cell activation (PubMed:27446912).  Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (By similarity).
What are the official names of this protein?
High mobility group protein HMGI-C, High mobility group AT-hook protein 2.
What is the protein family that this protein belongs to?
Belongs to the HMGA family.
What are the subcellular locations of this protein?
Nucleus.
Protein: RRF_AZOSB
Sequence: MISDLKKTTEQKMQKSIDALKTDLAKIRTGRAHTGLLDHVMVEYYGSMVPINQVANITLIDARTIGVQTWEKPMLGKVEKAIRDCDLGLNPANMGEIIRVPMPALTEERRRDLTKVVRQEGETAKVAVRNLRRDANQHLKDAVKDKTISEDDERRSQDDIQKLTDKYVAEIDKLLAQKEQELMQI
What is the function of this protein?
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis.  May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
What are the official names of this protein?
Ribosome-recycling factor, RRF, Ribosome-releasing factor.
What is the protein family that this protein belongs to?
Belongs to the RRF family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: WRKY4_ARATH
Sequence: MSEKEEAPSTSKSTGAPSRPTLSLPPRPFSEMFFNGGVGFSPGPMTLVSNMFPDSDEFRSFSQLLAGAMSSPATAAAAAAAATASDYQRLGEGTNSSSGDVDPRFKQNRPTGLMISQSQSPSMFTVPPGLSPAMLLDSPSFLGLFSPVQGSYGMTHQQALAQVTAQAVQANANMQPQTEYPPPSQVQSFSSGQAQIPTSAPLPAQRETSDVTIIEHRSQQPLNVDKPADDGYNWRKYGQKQVKGSEFPRSYYKCTNPGCPVKKKVERSLDGQVTEIIYKGQHNHEPPQNTKRGNKDNTANINGSSINNNRGSSELGASQFQTNSSNKTKREQHEAVSQATTTEHLSEASDGEEVGNGETDVREKDENEPDPKRRSTEVRISEPAPAASHRTVTEPRIIVQTTSEVDLLDDGYRWRKYGQKVVKGNPYPRSYYKCTTPGCGVRKHVERAATDPKAVVTTYEGKHNHDLPAAKSSSHAAAAAQLRPDNRPGGLANLNQQQQQQPVARLRLKEEQTT
What is the function of this protein?
Transcription factor that binds specifically to the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element.  Has a positive role in resistance to necrotrophic pathogens (e. g.  Botrytis cinerea), but a negative effect on plant resistance to biotrophic pathogens (e. g.  Pseudomonas syringae).
What are the official names of this protein?
Probable WRKY transcription factor 4, WRKY DNA-binding protein 4.
Protein: SYT_HERAR
Sequence: MITVRLPDGSQREFDTPVTVAQVAANIGAGLAKAALAGKVNGNVVDTSYLIEQDSDLSIITDKDAEGLDVIRHSTAHLLAYAVKELFPDAQVTIGPVIENGFYYDFSYKRPFTPEDLLAIEKKMAELAKKDEPVTRQVLPRDVAVEYFKSIGEAYKAEIIASIPADQDVSLYTEGKFTDLCRGPHVPSTGKLKVFKLMKLAGAYWRGDSKNEMLQRIYGTAWAKKEEQEAYLTMLEEAEKRDHRKLGRALDLFHFQEEAPGLIFWHPKGWTVWQQVEQYMRRVYQDNGYQEVKAPQILDRSLWEKSGHWENYKENMFTTESENRSYALKPMNCPGHVQIFASDLRSYRELPLRYGEFGQCHRNEPSGSLHGMMRVRGFTQDDGHIFCTEDQILDECVAFTALLQKVYRDFGFTNVIYKVATRPEKRVGSDEAWDKAEAALIASLDRSGCTYEISPGEGAFYGPKIEYTLKDAIGRMWQCGTIQVDFSMPARLGAEYVAEDNTKKIPVMLHRAILGSFERFIGMLIENHAGALPLWLAPVQIAVLNISDAQADYAQAVAQNLKKQGFRVHVDLRNEKITYKIREHSIQKLPYIIVIGDKERDAGTVAVRARGNVDLGVMPVDLLVERLNNEVEAKA
What is the function of this protein?
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).  Also edits incorrectly charged L-seryl-tRNA(Thr).
What are the official names of this protein?
Threonine--tRNA ligase, Threonyl-tRNA synthetase, ThrRS.
What is the protein family that this protein belongs to?
Belongs to the class-II aminoacyl-tRNA synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: Y7886_DICDI
Sequence: MCGGPNKWYIFLIGLVNINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKRFFFFG
What are the official names of this protein?
Putative uncharacterized protein DDB_G0277057.
Protein: RS15_RAT
Sequence: MAEVEQKKKRTFRKFTYRGVDLDQLLDMSYEQLMQLYSARQRRRLNRGLRRKQHSLLKRLRKAKKEAPPMEKPEVVKTHLRDMIILPEMVGSMVGVYNGKTFNQVEIKPEMIGHYLGEFSITYKPVKHGRPGIGATHSSRFIPLK
What is the function of this protein?
Component of the small ribosomal subunit.  The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
What are the official names of this protein?
40S ribosomal protein S15, RIG protein.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uS19 family.
Protein: PFDA_METB6
Sequence: MDQNEIETLQYYLKEYGQQAEVFAGQLELMENGRMEALAAIEALEALATSEDGTVLLQIGGGASLRAKVLEPEKVLLNIGSEVIVEKTSVDAIEYLKDRITELEASQKKVSEALEKLRAQTNEIAKRLEQGYRQAPGGSPVPHRHDHEDHDEE
What is the function of this protein?
Molecular chaperone capable of stabilizing a range of proteins.  Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
What are the official names of this protein?
Prefoldin subunit alpha, GimC subunit alpha.
What is the protein family that this protein belongs to?
Belongs to the prefoldin alpha subunit family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: HEMA_I76AL
Sequence: MNTQILILAISAFLCVRADKICLGHHAVSNGTKVDTLTEKGIEVVNATETVEQKNIPKICSKGKQTIDLGQCGLLGTTIGPPQCDQFLEFSANLIIERREGDDICYPGKFDNEETLRQILRKSGGIKKENMGFTYTGVRTNGETSACRRSRSSFYAEMKWLLSNTDNGVFPQMTKSYKNTKREPALIIWGIHHSGSTAEQTRLYGSGNKLVTVWSSKYQRSFAPNPGPRPQINGQSGRIDFYWLMLDPNDTVTFSFNGAFIAPDRASFLRGKSLGIQSDAQLDNNCEGECYHIGGTIISNLPFQNINSRAIGKCPRYVKQKSLMLATGMKNVPENSTHKQLTHHMRKKRGLFGAIAGFIENGWEGLIDGWYGYRHQNAQGEGTAADYKSTQSAINQITGKLNRLIEKTNQQFELIDNEFNEIEKQIGNVINWTRDSIIEVWSYNAEFLVAVENQHTIDLTDSEMNKLYEKVRRQLRENAEEDGNGCFEIFHQCDNDCMASIRNNTYDHKKYRKEAIQNRIQIDAVKLSSGYKDIILWFSFGASCFLFLAIAMVLAFICIKNGNMRCTICI
What is the function of this protein?
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell.  This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway.  Plays a major role in the determination of host range restriction and virulence.  Class I viral fusion protein.  Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.  Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide.  Several trimers are required to form a competent fusion pore.
What are the official names of this protein?
Hemagglutinin.
What is the protein family that this protein belongs to?
Belongs to the influenza viruses hemagglutinin family.
What are the subcellular locations of this protein?
Virion membrane; Single-pass type I membrane protein. Host apical cell membrane; Single-pass type I membrane protein. Note=Targeted to the apical plasma membrane in epithelial polarized cells through a signal present in the transmembrane domain. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts.
Protein: SMC2_SCHPO
Sequence: MKIEELIIDGFKSYAVRTVISNWDDQFNAITGLNGSGKSNILDAICFVLGITNMSTVRAQNLQDLIYKRGQAGITRASVTIVFNNRDPASSPIGFENHPQVSVTRQIIMGGTSKYLINGHRALQQNVQNLFQSVQLNINNPNFLIMQGRITKVLNMKATEILSMIEEASGTRMFEERKEKAFRTMQRKEAKVEEINTLLREEIEPRLTKLRTEKKTFLEYQHIYNDLERLSHLCTAYDYYKLSLKVEELTVQASQKHSHIAEMESSLQTSKQEVLILKEKIKKIEDERMRQMSVSSDRTLDSQLQTVNENITRISTSIELKNTALEEEHGDLQQIRGKAKELETLLRGKRKRLDEVLSVYEKRKDEHQSISKDFKSQEELISSLTTGLSTTEGHETGYSRKLHEARDTLNDFKAEKETNRLKLEGLNKQISLTKPKKAEATKRCDQLNREIDILQNHVEKLKMSLKNTNSDITGEDVLQQKLKQLAKDRGNLLNELDALKSKLAYMEFTYTDPTPNFDRSKVKGLVAQLLTLNEENYDKQTALEITAGGRLYNLIVETEKIGAQLLQKGNLKRRVTIIPLNKITSFVASAERVGAAKKISNNKAQLALELIGYDDELLPAMQYVFGSTLVCDTPESAKKVTFHPSVKLKSVTLDGDVYDPSGTLTGGSVNKSAGPLLQIQKLNSLQLKLQVVTSEYEKLETQLKDLKTQNANFHRLEQEIQLKQHELTLLIEQRETDSSFRLLSDYQQYKDDVKDLKQRLPELDRLILQSDQAIKKIERDMQEWKHNKGSKMAELEKEFNQYKHKLDEFTPILEKSENDYNGVKLECEQLEGELQNHQQSLVQGESTTSLIKTEIAELELSLVNEEHNRKKLTELIEIESAKFSGLNKEIDSLSTSMKTFESEINNGELTIQKLNHEFDRLEREKSVAITAINHLEKENDWIDGQKQHFGKQGTIFDFHSQNMRQCREQLHNLKPRFASMRKAINPKVMDMIDGVEKKEAKLRSMIKTIHRDKKKIQDTVKSIDRFKRSALEKTWREVNSSFGEIFDELLPGNSAELQPPENKEFTDGLEIHVKIGSIWKDSLAELSGGQRSLVALALIMSLLKYKPAPMYILDEIDAALDLSHTQNIGRLIKTKFKGSQFIIVSLKEGMFTNANRLFHVRFMDGSSVVQAR
What is the function of this protein?
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.  The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
What are the official names of this protein?
Structural maintenance of chromosomes protein 2, Cell untimely torn protein 14, Chromosome segregation protein cut14.
What is the protein family that this protein belongs to?
Belongs to the SMC family. SMC2 subfamily.
What are the subcellular locations of this protein?
Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, condensin associates with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase.
Protein: INA17_YEAS7
Sequence: MLKRRSNALITLSRTKLFPITTVAYYHRRLLNQQRRAVSTSPKKEIKSLEDLANLDSLDGVDTELIRDLINEHTTKLNIKKELDMLKKFSQEEESGHEIPVKRFIRPLWMFILMGSSVYLLLHFSWWKLEHEERESQLKKEVEILEHQLNELIIQDKTHNTSRGKGSNESTHMKPWYRRWFW
What is the function of this protein?
Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase.  INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain.
What are the official names of this protein?
Inner membrane assembly complex subunit 17, Altered inheritance of mitochondria protein 43, Found in mitochondrial proteome protein 14.
What is the protein family that this protein belongs to?
Belongs to the INA17 family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Single-pass membrane protein.
Protein: PURA_LACLA
Sequence: MPSVVVVGTQWGDEGKGKITDFLSSNAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLIEEIAYLAENGVSAESLRISDRAHVILPYHKKLDFLQEEAKGDKKIGTTIKGIGPAYMDKAARVGIRVADLLDKEIFEERLRTNLEAKNREFVKMYDSEPIEFEEIFEEYYEYGQQLKKYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKISKVVGVCKAYTSRVGDGPFPTELFDEVGHQIREVGHEYGTTTGRPRRVGWFDSVVMRHAKRVSGLTNLSLNSIDVLSGLETVKICVAYERSNGEQITHYPASLKELADCKPIYEELPGWSEDITSCRTLEELPEAARNYVRRVGELVGVRISTFSVGPGREQTNVLESVWGV
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PGLR2_ASPNG
Sequence: MHSFASLLAYGLAASATLASASPIEARGSCTFKTAAAAKAGKAGCSTITLDNIEVPAGTTLDLTGLTSGTKVIFEGTTTFDYEEWAGPLISMSGKDITVTGASGHLINCDGARWWDGKGTSGKKKPKFFYAHGLDSSSITGLNIKNTPLMAFSVQADDITLTDITINNADGDTLGGHNTDAFDVGNSVGVNIIKPWVHNQDDCLAINSGENIWFTSGTCIGGHGLSIGSVGGRSNNVVKNVTIEHSTVSNSENAVRIKTVSGATGSVSEITYSNIVMSGISDYGVVIQQDYEDGKPTGKPTNGVTITDVKLESVTGTVDSKATDIYLLCGSGSCSDWTWDDVKVTGGKKSTACKNYPSVASC
What is the function of this protein?
Involved in maceration and soft-rotting of plant tissue.  Hydrolyzes the 1,4-alpha glycosidic bonds of de-esterified pectate in the smooth region of the plant cell wall.
What are the official names of this protein?
Endopolygalacturonase II, EPG-II, Pectinase 2, Polygalacturonase II, PG-II, Polygalacturonase X2.
What is the protein family that this protein belongs to?
Belongs to the glycosyl hydrolase 28 family.
What are the subcellular locations of this protein?
Secreted.
Protein: MOBA_STAS1
Sequence: MKAIILAGGQSERFGEPKAFAQINAQPFYKRIIDVLEGTNMFNQIIISTNETLASQFDHSDIIIDEDQNKDKGPLAGIQSVIQHYESEELFFVVSVDTPMISQKAVSKLYQFMVEHLIEDQLDIAGFKEKGRPIPTIAFYSPHTLPYIDDALNSNDYSLKSVYNKVKSDWLDVNLIESPDYWYKNINYQQDLDSLQQDILNR
What is the function of this protein?
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
What are the official names of this protein?
Probable molybdenum cofactor guanylyltransferase, MoCo guanylyltransferase, GTP:molybdopterin guanylyltransferase, Mo-MPT guanylyltransferase, Molybdopterin guanylyltransferase, Molybdopterin-guanine dinucleotide synthase, MGD synthase.
What is the protein family that this protein belongs to?
Belongs to the MobA family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RL30_STRP8
Sequence: MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVVKEDNAAIRGMVTAISHLVTVEDVK
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: FKB10_HUMAN
Sequence: MFPAGPPSHSLLRLPLLQLLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPGQDPEKTIGDMFQNQDRNQDGKITVDELKLKSDEDEERVHEEL
What is the function of this protein?
PPIases accelerate the folding of proteins during protein synthesis.
What are the official names of this protein?
Peptidyl-prolyl cis-trans isomerase FKBP10, PPIase FKBP10, 65 kDa FK506-binding protein, 65 kDa FKBP, FKBP-65, FK506-binding protein 10, FKBP-10, Immunophilin FKBP65, Rotamase.
What are the subcellular locations of this protein?
Endoplasmic reticulum lumen.
Protein: RL30_SALPA
Sequence: MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAVRGMVNAVSFMVKVEE
What are the official names of this protein?
50S ribosomal protein L30.
What is the protein family that this protein belongs to?
Belongs to the universal ribosomal protein uL30 family.
Protein: PPX1_MYCLE
Sequence: MRLGVLDVGSNTVHLLVVDAYRGGHPTPMSSTKATLRMVEATDSSGKITKRAADKLVSTIGEFAKIAVSSGCAELMAFATSAVREAGNSDDVLSRVRKETGVRLQVLRGVDESRLTFLAVRRWFGWSAGRIINLDIGGGSLELSNGVDEEPEVALSLPLGAGRLTREWLPDDPPGRRRVAMLRDWLDSELSDASVTVLEAGKPDLAVATSKTFRSLARLTGAAPSAAGPRAKRALTVNGLRQLIAFISRMTASDRAELEGISTERAPQIVAGALVAEASMRALSIETVDICPWALREGLILRKLDSEADGTALVQTSVRDTRGQEVDRNAANRSRGDKT
What is the function of this protein?
Degradation of inorganic polyphosphates (polyP).  Releases orthophosphate processively from the ends of the polyP chain.
What are the official names of this protein?
Exopolyphosphatase 1, ExopolyPase 1.
What is the protein family that this protein belongs to?
Belongs to the GppA/Ppx family.
Protein: GATB_HELPJ
Sequence: MPFEAVIGLEVHVQLNTKTKIFCSCSTSFGETPNSNTCPVCLGLPGALPVLNKEVVKKAIQLGTAIEAHINQYSIFARKNYFYPDLPKAYQISQFEVPIVSDGKLEIDTKEGAKIVRIERAHMEEDAGKNIHEGSYSLVDLNRACTPLLEIVSKPDMKNSEEAIAYLKKLHAIVRFIGISDANMQEGNFRCDANVSIRPKGDEKLYTRVEIKNLNSFRFIAKAIEYEIERQSVAWENGRYNEEVVQETRLFDTAKGITLSMRNKEESADYRYFKDPDLYPVFIDEKLLKEAQKINELPGAKKIRYMKDFNLKEDDANLLVSDPLLAEYFESMLNLGVKAKTSVTWLCVELLGRLKAEVTLENCGISAHALGALAKRIDEGKISGKSAKDVLDRLLEEQGGDVDTLIEQMGLSQVNDTEAIVKVIEEVLKNNADKVLEYKSGKDKLFGFFVGQAMKNLKGANPSVVNAILKEKLD
What is the function of this protein?
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases.  The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity).
What are the official names of this protein?
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, Asp/Glu-ADT subunit B.
What is the protein family that this protein belongs to?
Belongs to the GatB/GatE family. GatB subfamily.
Protein: EFPL_SALTI
Sequence: MPRANEIKKGMVLNYNGKLLIVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLSRRGVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLSTGLVIQVPEYLSAGEKIRIHIEERRYMGRAD
What are the official names of this protein?
Elongation factor P-like protein.
What is the protein family that this protein belongs to?
Belongs to the elongation factor P family.