PharMolix/UniProtQA huggingface dataset:
Protein: UVRB_STAES
Sequence: MVEHVPFKLKSEFEPQGDQPQAIQKIVDGVNERKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSSLFERDDVIIIASVSCIYGLGNPEEYKNLVVSVRVGMEMERSELLRKLVDVQYSRNDIDFQRGTFRVRGDVVEIFPASREEMCIRVEFFGDEIDRIREVNYLTGEVIREREHFTIFPASHFVTREEKMKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQIRGMYNGDRARKQVLIDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYELEHTDEMVEQIIRPTGLLDPKIDVRPTENQIDDLLSEIQDRVDKDERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDAIVGINLLREGIDIPEVSLVVILDADKEGFLRSDRSLIQTIGRAARNDKGEVIMYADKITDSMQYAIDETQRRREIQIAHNKEHGITPKTINKKIHDVISATVESDETNQQQQTELPKKMTKKERQKTIENIEKEMKKAAKDLDFEKATELRDMLFELKAEG
What is the function of this protein?
The UvrABC repair system catalyzes the recognition and processing of DNA lesions.  A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities.  Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer.  DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands.  Then UvrB probes one DNA strand for the presence of a lesion.  If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed.  This complex is subsequently bound by UvrC and the second UvrB is released.  If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
What are the official names of this protein?
UvrABC system protein B, Protein UvrB, Excinuclease ABC subunit B.
What is the protein family that this protein belongs to?
Belongs to the UvrB family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: CLCB_CITK8
Sequence: MFRRLLIATIIGILAALAVAGFRHAMLVLEWLFLRNDTGSLVNAATNLSPWRRLITPAVGGLAAGALLWGWQKMNQQRPHAPTDYMEALQTDGQFDYGASLVKSLASLLVVASGSAIGREGAMILLAALAASCFAQRCTPREEWKLWIACGAAAGMASAYHAPLAGSLFIAEILFGTLMLASLGPVVISAVVALLTTHLLSGGNALLYTVHLSLDLHVREYAMIISTGLVAGVCGPLFMWLMTTTHNGFIRLKLSPPWQLALGGFIVGLLSLLTPAVWGNGYSVVQSFLLSPPLLSVIAGIFICKLLAVLASSGSGAPGGVFTPTLFIGLSIGMLYGRMWGFWLPGADEMAILLGLTGMATLLAATTHAPMMSTLMICEMTGEYRLLPGLLIACVVASVLSRTLREDSVYRQHTAEH
What is the function of this protein?
Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response.
What are the official names of this protein?
Voltage-gated ClC-type chloride channel ClcB.
What is the protein family that this protein belongs to?
Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily.
What are the subcellular locations of this protein?
Cell inner membrane; Multi-pass membrane protein.
Protein: PP2A_HEVBR
Sequence: MPSHGDLDRQIEHLMECKPLPEARGQTLCDQARAILVEEWNVQPVKCPVTVCGDIHGQFYDLIELFRIGGNAPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRDRITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALIESQIFCLHGGLSPSLDTLDNIRALDRIQEVPHEGPMCDLLWSDPDDRCGWGISPRGAGYTFGQDIAAQFNHTNGLTLISRAHQLVMEGYNWCQEKNVVTVFSAPNYCYRCGIMAAILEIGENMAQNFLQFDPAPRQIEPDTTRKTPDYFL
What are the official names of this protein?
Serine/threonine-protein phosphatase PP2A catalytic subunit.
What is the protein family that this protein belongs to?
Belongs to the PPP phosphatase family. PP-2A subfamily.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: COX23_CANGA
Sequence: MAADEDIIKDGNYDPHVQTDKDKVDYAPKGVDTTEYRYYPDNPESTLNKYRFAMKDHSQYYDPCQESAKMSFKCLELNDYDRDQCKEYFDAYRECKKQWLEARRKDRTNWS
What is the function of this protein?
Required for the assembly of cytochrome c oxidase.
What are the official names of this protein?
Cytochrome c oxidase-assembly factor COX23, mitochondrial.
What is the protein family that this protein belongs to?
Belongs to the COX23 family.
What are the subcellular locations of this protein?
Mitochondrion intermembrane space.
Protein: LEUD_BORA1
Sequence: MQAFTFHEGLVAPLDRENVDTDLIIPKQFLKSIKRTGFGPNLFDELRYLDHGEPGMDNSKRPLNPDFVLNQPRYQGASILLGRKNFGCGSSREHAPWALQQYGFRAIIAPSYADIFFNNSFKNGLLPIVLTELEVARLFDEVKAFPGYKLKVDLERQVVIAADGREMAFEVDAFRKYCLLNGFDDIGLTLRQSDKIRAFEAERLARHPWLESRPVA
What is the function of this protein?
Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
What are the official names of this protein?
3-isopropylmalate dehydratase small subunit, Alpha-IPM isomerase, IPMI, Isopropylmalate isomerase.
What is the protein family that this protein belongs to?
Belongs to the LeuD family. LeuD type 1 subfamily.
Protein: TRAR_SINFN
Sequence: MSVNGNLRSLIDMLEAAQDGHMIKIALRSFAHSCGYDRFAYLQKDGTQVRTFHSYPGPWESIYLGSDYFNIDPVLAEAKRRRDVFFWTADAWPARGSSPLRRFRDEAISHGIRCGVTIPVEGSYGSAMMLTFASPERKVDISGVLDPKKAVQLLMMVHYQLKIIAAKTVLNPKQMLSPREMLCLVWASKGKTASVTANLTGINARTVQHYLDKARAKLDAESVPQLVAIAKDRGLV
What is the function of this protein?
Positive regulation of conjugal transfer.  TraR activates target genes in the presence of AAI and also activates traR and traI themselves (By similarity).
What are the official names of this protein?
Probable transcriptional activator protein TraR.
What is the protein family that this protein belongs to?
Belongs to the autoinducer-regulated transcriptional regulatory protein family.
Protein: CYB_SHEEP
Sequence: MINIRKTHPLMKIVNNAFIDLPAPSNISSWWNFGSLLGICLILQILTGLFLAMHYTPDTTTAFSSVTHICRDVNYGWIIRYMHANGASMFFICLFMHVGRGLYYGSYTFLETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFIFPFIIAALAMVHLLFLHETGSNNPTGIPSDTDKIPFHPYYTIKDILGAILLILILMLLVLFTPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLVIMPLLHTSKQRSMMFRPISQCMFWILVADLLTLTWIGGQPVEHPYIIIGQLASIMYFLIILVMMPVASIIENNLLKW
What is the function of this protein?
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain.  The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c.  Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
What are the official names of this protein?
Cytochrome b, Complex III subunit 3, Complex III subunit III, Cytochrome b-c1 complex subunit 3, Ubiquinol-cytochrome-c reductase complex cytochrome b subunit.
What is the protein family that this protein belongs to?
Belongs to the cytochrome b family.
What are the subcellular locations of this protein?
Mitochondrion inner membrane; Multi-pass membrane protein.
Protein: EPMB_HAEIN
Sequence: MRILPQEPVIREEQNWLTILKNAISDPKLLLKALNLPEDDFEQSIAARKLFSLRVPQPFIDKIEKGNPQDPLFLQVMCSDLEFVQAEGFSTDPLEEKNANAVPNILHKYRNRLLFMAKGGCAVNCRYCFRRHFPYDENPGNKKSWQLALDYIAAHSEIEEVIFSGGDPLMAKDHELAWLIKHLENIPHLQRLRIHTRLPVVIPQRITDEFCTLLAETRLQTVMVTHINHPNEIDQIFAHAMQKLNAVNVTLLNQSVLLKGVNDDAQILKILSDKLFQTGILPYYLHLLDKVQGASHFLISDIEAMQIYKTLQSLTSGYLVPKLAREIAGEPNKTLYAE
What is the function of this protein?
With EpmA is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'.  EpmB appears to act before EpmA.  Displays lysine 2,3-aminomutase activity, producing (R)-beta-lysine from (S)-alpha-lysine (L-lysine) (By similarity).
What are the official names of this protein?
L-lysine 2,3-aminomutase, LAM, EF-P post-translational modification enzyme B.
What is the protein family that this protein belongs to?
Belongs to the radical SAM superfamily. KamA family.
Protein: SUCC_BRUME
Sequence: MNIHEYQAKRLLHTYGAPIANGVAVYSVEQAEEWAKTLPGPLYVVKSQIHAGGRGKGKFKELPADAKGGVRLAKSVEEVVANAKEMLGNTLVTKQTGEAGKQVNRLYIEDGADIERELYLSILIDRSVGRPAFVVSTEGGMDIEAVAEETPEKIVTVAIDPAKGVTDEDANKLADALKLEGGAREDGLKLFPILYKAFTEKDMSLLEINPLIVMTNGRVRVLDAKVSFDNNALFRHPDIVELRDLTEEDPKEIEASKYDLAYVALDGNIGCMVNGAGLAMATMDIIKLYGAEPANFLDVGGGASKEKVTAAFKIITADPAVEGILVNIFGGIMKCDVIAEGVIAAVKEVGLKVPLVVRLEGTNVELGKKIINESGLNVISADDLDDAAQKIVAAVKGN
What is the function of this protein?
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA.  The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
What are the official names of this protein?
Succinate--CoA ligase [ADP-forming] subunit beta, Succinyl-CoA synthetase subunit beta, SCS-beta.
What is the protein family that this protein belongs to?
Belongs to the succinate/malate CoA ligase beta subunit family.
Protein: PRIL_PYRHO
Sequence: MLDPFSEKAKELLKGFGSINDFMDAIPKIVSVDDVIERIRVVKNEKLIDKFLDQDNVMDLAQFYALLGALSYSPYGIELELVKKANLIIYSERLKRKKEIKPEEISIDVSTAIEFPTEDVRKIERVYGKIPEYTMKISDFLDLVPDEKLANYYIYEGRVYLKREDLIRIWSKAFERNVERGVNMLYEIRDELPEFYRKVLGEIQAFAEEEFGRKFGEIQGGKLRPEFFPPCIKNALKGVPQGIRNYAITVLLTSFLSYARICPNPPRRNVRVKDCIKDIRVITEEILPIIIEAANRCSPPLFEDQPNEIKNIWYHLGFGYTANPSLEDSGNSTWYFPPNCEKIRANAPQLCTPDKHCKYIRNPLTYYLRRLYLEGRRNAPKRGNKRGKKELLHQ
What is the function of this protein?
Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.  Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability.  The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis.  May also play a role in DNA repair.
What are the official names of this protein?
DNA primase large subunit PriL, DNA primase 46 kDa subunit, p46.
What is the protein family that this protein belongs to?
Belongs to the eukaryotic-type primase large subunit family.
Protein: PNLN_PANAR
Sequence: MKNKAVLMLMALFLVAVTQVHGDPEPSYKARSCTAYGYFCMIPPRCRGTVVANHWCRARGHICCSSPSNVYGKNQLLAA
What is the function of this protein?
Involved in the melanization cascade in response to lipopolysaccharide (LPS).  In vitro, reversibly and competitively inhibits trypsin (Ki=8. 6 nM) but not serine proteases chymotrypsin, elastase, subtilisin, thrombin and plasmin, cysteine peptidase papain or metallopeptidase carboxypeptidase A.
What are the official names of this protein?
Panulirin.
Protein: UNG_GAHVM
Sequence: MAQLDLTGLTETSKMIVGECHVELKRCAEPPLAADEPMPKKCRRPAGPPKGFISTRGDTSPSSDNNHIHSIQSLTNGDSCVQPWDIIANAYNIHENWKQLLLPELCCLRGSEILAEYERRAITEEVYPPKMDIFAWTRYCAPESVKAVIVGQDPYANPGQAHGLAFSVKQGVAIPPSLKNILLAVKACYPSADLGNHGCLEAWSKRGVLLLNSVLTVKRGDPGSHHSVGWQFFIRNILRRLSSTTRGIVFMLWGAQAQTMYFQTDYDDRHLVLKYSHPSPLSRKPFATCTHFKEANDFLSKIGRGCIDWSLTA
What is the function of this protein?
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines.  Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes.
What are the official names of this protein?
Uracil-DNA glycosylase, UDG, UNG.
What is the protein family that this protein belongs to?
Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
What are the subcellular locations of this protein?
Host nucleus.
Protein: GLT11_MOUSE
Sequence: MGSITVRYFCYGCLFTSATWTVLLFIYFNFSEVTQPLRNVPIKGSGPHGPFPKKFYPRFTRGPGRVLDPQFKANRIDRLMNNHIEDPDKGLSKSSSELGMIFNERDQELRDLGYQKHAFNMLISNRLGYHRDVPDTRNAECRRKSYPTDLPTASIVICFYNEAFSALLRTVHSVVDRTPAHLLHEIILVDDSSDFDDLKGELDEYIQRYLPAKVKVIRNMKREGLIRGRMIGAAHATGEVLVFLDSHCEVNVMWLQPLLAIILEDPHTVVCPVIDIISADTLAYSSSPVVRGGFNWGLHFKWDLVPVSELGGPDGATAPIRSPTMAGGLFAMNRQYFNDLGQYDSGMDIWGGENLEISFRIWMCGGKLFILPCSRVGHIFRKRRPYGSPEGQDTMTHNSLRLAHVWLDEYKEQYFSLRPDLKNKSFGNISERVELRKKLGCQSFKWYLDNIYPEMQIPGPNAKPQQPVLINRGPKRPRVLQRGRLYHLQTNKCLVAQGRSSQKGGLVLLKTCDYGDPTQVWIYNEDHELILNNLLCLDMSETRSSDPPRLMKCHGSGGSQQWTFGKNNRLYQVSVGQCLRVMDLMDQKGYVGMAICDGSSSQQWRLEG
What is the function of this protein?
Polypeptide N-acetylgalactosaminyltransferase that catalyzes the initiation of protein O-linked glycosylation and is involved in left/right asymmetry by mediating O-glycosylation of NOTCH1.  O-glycosylation of NOTCH1 promotes activation of NOTCH1, modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).  Polypeptide N-acetylgalactosaminyltransferases catalyze the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.  Displays the same enzyme activity toward MUC1, MUC4, and EA2 than GALNT1.  Not involved in glycosylation of erythropoietin (EPO) (By similarity).
What are the official names of this protein?
Polypeptide N-acetylgalactosaminyltransferase 11, Polypeptide GalNAc transferase 11, GalNAc-T11, pp-GaNTase 11, Protein-UDP acetylgalactosaminyltransferase 11, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 11.
What is the protein family that this protein belongs to?
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
What are the subcellular locations of this protein?
Golgi apparatus membrane; Single- pass type II membrane protein.
Protein: CRCB3_METBF
Sequence: MYTILLVGIGGFIGATLRYVFGGWIQNSFVNFPVGTLTINTIGSFFLGLIMYFSEYQGLFSDQTRIFLTIGILGAFTTLSTFGYESFRLLDDSKLMLMSINVVSTVLFSMMAVYLGKTVALGVSSYLLGGMK
What is the function of this protein?
Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
What are the official names of this protein?
Putative fluoride ion transporter CrcB 3.
What is the protein family that this protein belongs to?
Belongs to the CrcB (TC 9.B.71) family.
What are the subcellular locations of this protein?
Cell membrane; Multi-pass membrane protein.
Protein: PURA_PSYIN
Sequence: MGNNVVVLGTQWGDEGKGKVVDLLTDKAQWVVRYQGGHNAGHTLVIDGEKTVLHLIPSGILRDNVKCVIGNGVVLSPEALLEELKMLEDRGVPAKERLHISEGCPLILPYHIALDAARELARGDKAIGTTGRGIGPAYEDKVARRGLRVDDLFNMETFAVKLKEVIDYHNFQLVNYYKVEAVNFDEVLKQVQSVADLLISLVIDVTDELDKARLRGENILFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGFGPAHIDYVLGIVKAYTTRVGSGPFPTELYDGVDKLDPAGKHLGTVGHEFGATTGRLRRTGWFDAVAIKRAVQLNSITGFCLTKLDVLDGLEEIKICTAYKMPGDKLVDVPPMSAEGYEQAVPVYETVPGWTESSFGVTSFDALPKNAQAYVRRLEEITGIPMDIISTGPDRNETMIQVNPFN
What is the function of this protein?
Plays an important role in the de novo pathway of purine nucleotide biosynthesis.  Catalyzes the first committed step in the biosynthesis of AMP from IMP.
What are the official names of this protein?
Adenylosuccinate synthetase, AMPSase, AdSS, IMP--aspartate ligase.
What is the protein family that this protein belongs to?
Belongs to the adenylosuccinate synthetase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ISPD_MOUSE
Sequence: MEPGPCSRPAEPGHCVSGPAGAGSAFPESPLSVAGAEPGNRPGTVAAVLPAGGCGERMGVRTPKQFCRVLERPLISYTLQAMERVCWIKDIVVTVTGENMEAMRSIIQRYGHKRISLAEAGATRHRSIFNGLKALAEDQPDCKLTKPEVVIIHDAVRPFVEEDILLRVVLAAKEHGAAGAIRPLVSTVISPSADGHLDHSLDRAKHRASEMPQAFLFDVIYEAYQQCSDFDLEFGTECLQLALKYCHRKAKLVEGPPALWKVTYKQDLCAAEAMIKEKISQEICVVMNTKDEESVGHLLEEALRKELNCMKITSTVMDHIGGDIRNFIEQCYSFICVNVVSPDSQETRKLLRILEESSLPLLYPVVVVLVHCFDFTSVPLAQKMESLVWIRGLAKEVKERNILLSGLLLNYSQDEQKLQESLGQSAAIIAALVKERNSALVGQLLVA
What is the function of this protein?
Cytidylyltransferase required for protein O-linked mannosylation (By similarity).  Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate (By similarity).  CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity).  Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively (By similarity).  Not involved in dolichol production (By similarity).
What are the official names of this protein?
D-ribitol-5-phosphate cytidylyltransferase, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein, Isoprenoid synthase domain-containing protein.
What is the protein family that this protein belongs to?
Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
What are the subcellular locations of this protein?
Cytoplasm, cytosol.
Protein: SCPB_CLOB1
Sequence: MNKDHEEQLEINEVSQKNKYKSIIESLLFMSGEPINIKDLATILNCKQDKVSSLLNEMNNSYVGKDRGIKILIHNRAVQLVTKPENSIYVEKLLKTNVRQSLSQAALETLSIIAYKQPITRVAIDEIRGVKSDRAIYTLLEKNIIKECGRLDVPGKPILYGTTEEFLKFFGLDSIEAIPNLEDLLKEFSKEEN
What is the function of this protein?
Participates in chromosomal partition during cell division.  May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
What are the official names of this protein?
Segregation and condensation protein B.
What is the protein family that this protein belongs to?
Belongs to the ScpB family.
What are the subcellular locations of this protein?
Cytoplasm. Note=Associated with two foci at the outer edges of the nucleoid region in young cells, and at four foci within both cell halves in older cells.
Protein: PSBK_SKECO
Sequence: MESLLLARLPEAYVVFSPLVDVFPVIPVFFLLLAFVWQAAVGFR
What is the function of this protein?
One of the components of the core complex of photosystem II (PSII).  PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation.  It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation.
What are the official names of this protein?
Photosystem II reaction center protein K, PSII-K.
What is the protein family that this protein belongs to?
Belongs to the PsbK family.
What are the subcellular locations of this protein?
Plastid, chloroplast thylakoid membrane; Single-pass membrane protein.
Protein: GSKIP_XENTR
Sequence: MEVDYNPMDLPVNTVYEDESEFRDLEGTDVKDMCLEAEAIVNDVLFAVGNMFVSKTLPCAVDVAYINVEIKEGTRYCLELTDAGLRVAGYAFDHLAEGLCSQYHETVYSLLDSLSPAYREAFGNALLQRLEALKRDGQS
What are the official names of this protein?
GSK3-beta interaction protein, GSKIP.
What is the protein family that this protein belongs to?
Belongs to the GSKIP family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: PNP_CUPTR
Sequence: MSMFNKVVKEFQWGQHKVRMETGEIARQAGGAVLVDVEDTVVLATVVAAKSPKPGQDFFPLTVDYIEKTYAAGKIPGGFFKREGRPSENETLTSRLIDRPLRPLFPEGFYNDVQVVVHVVSLNPEVPADIPALIGASAALAVSGIPFNGPVGAARVGYKDGQYLLNPTRSQIATSDLDLVVAGTERAVLMVESEANQLSEDVMLGAVVYGHEQMQTAINAIHELVREGGKPEWDWAPAAKNEPLIAKVTEVALPLLQEAYQLRQKSARSQKLKEVSANVAAALAEAGVEADKVEVGNIMFDLEAKIVRGQILNGEPRIDGRDTRTVRPIEIRSSVLPRAHGSALFTRGETQALVVATLGTKSDEQIIDALAGEYRDRFMLHYNMPPFATGETGRVGSPKRREIGHGRLAKRALIPVLPKEDEFAYTIRLVSEITESNGSSSMASVCGGCLALMDAGVPVKAHVAGVAMGLILEGNKFAVLTDILGDEDHLGDMDFKVAGTDNGITALQMDIKVQGITKEIMQVALAQAKEGRLHILSNMQEAMGHARTELSAHAPRMITMKIHPDKIREVIGKGGSTIQALTKETGTTIDIQEDGTITIASTSTEGMAEAKRRIEGITAEAEVGKIYAGTVLKLLDFGAIVNILPGKDGLLHISEIVNERVKDIKDWLKEGQQVRVKLIQADEKGRLRLSLKAALAEEGGSISPINAGESAAPAAPAGGSEQQ
What is the function of this protein?
Involved in mRNA degradation.  Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.
What are the official names of this protein?
Polyribonucleotide nucleotidyltransferase, Polynucleotide phosphorylase, PNPase.
What is the protein family that this protein belongs to?
Belongs to the polyribonucleotide nucleotidyltransferase family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: ELBP_ECOLX
Sequence: MNKVKCYVLFTALLSSLYAHGAPQTITELCSEYRNTQIYTINDKILSYTESMAGKREMVIITFKSGETFQVEVPGSQHIDSQKKAIERMKDTLRITYLTETKIDKLCVWNNKTPNSIAAISMKN
What is the function of this protein?
The biological activity of the toxin is produced by the A chain, which activates intracellular adenyl cyclase.
What are the official names of this protein?
Heat-labile enterotoxin B chain, LT-B, porcine, LTP-B.
Protein: HSP83_DROPE
Sequence: MPEEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLIADRVTVTSKNNDDEQYVWESXXXGSFTXKADNXEPLXRGTKIXLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKDDEAKKDMDTDEPKIEDVGEDEDADKKDKDGKKKKTIKEKY
What is the function of this protein?
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.  Undergoes a functional cycle that is linked to its ATPase activity.  This cycle probably induces conformational changes in the client proteins, thereby causing their activation.  Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.  Required for piRNA biogenesis by facilitating loading of piRNAs into PIWI proteins (By similarity).
What are the official names of this protein?
Heat shock protein 83, HSP 82.
What is the protein family that this protein belongs to?
Belongs to the heat shock protein 90 family.
What are the subcellular locations of this protein?
Cytoplasm.
Protein: RUVA_STAA8
Sequence: MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKHLDHEVLIHTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIENENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAMLALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS
What is the function of this protein?
The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR).  RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure.  The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.  HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA.
What are the official names of this protein?
Holliday junction branch migration complex subunit RuvA.
What is the protein family that this protein belongs to?
Belongs to the RuvA family.
Protein: IPI1_CANAL
Sequence: MASKRKRKEKQKDFAKAKLKVGKTAQKPDNYTDTSFKSKTISLPNQSIASSSNYGASSGASRSSLSTGPSLAVLTHQLSLTKHHSSNTRKEVLNYLQTHLPENPSYYKNIMTSILPLILDEDKEVRKALMSLLSAIFAKQPGLIDLHLRSTILFILSAMSHIIPNIRTTSTHFLRIIVENSHGNLINSYFVKIMRNWFVLMGWSLNEQDSKQLSMAVTTLSITAMNANSKQARIGHLQNLNKFLSKTLQHDQDKDKNKDMKLNITIHPQSYKYLLTDTVQPYQPLKLFVKEFKSEGSGSNGSGISMLDLNTISTEDLDTRKKIMNDVFKPLMIKNLNTFVKEGGEIGREANNCISIVTQACTSSSE
What is the function of this protein?
Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
What are the official names of this protein?
Pre-rRNA-processing protein IPI1-1.
What is the protein family that this protein belongs to?
Belongs to the IPI1/TEX10 family.
What are the subcellular locations of this protein?
Nucleus.
Protein: ACMA_GORST
Sequence: MSTTTLDAAVIGTGVAGLYELHMLREQGLEVRAYDKASGVGGTWYWNRYPGARFDSEAYIYQYLFDEDLYKGWSWSQRFPGQEEIERWLNYVADSLDLRRDISLETEITSAVFDEDRNRWTLTTADGDTIDAQFLITCCGMLSAPMKDLFPGQSDFGGQLVHTARWPKEGIDFAGKRVGVIGNGATGIQVIQSIAADVDELKVFIRTPQYALPMKNPSYGPDEVAWYKSRFGELKDTLPHTFTGFEYDFTDAWEDLTPEQRRARLEDDYENGSLKLWLASFAEIFSDEQVSEEVSEFVREKMRARLVDPELCDLLIPSDYGFGTHRVPLETNYLEVYHRDNVTAVLVRDNPITRIRENGIELADGTVHELDVIIMATGFDAGTGALTRIDIRGRDGRTLADDWSRDIRTTMGLMVHGYPNMLTTAVPLAPSAALCNMTTCLQQQTEWISEAIRHLRATGKTVIEPTAEGEEAWVAHHDELADANLISKTNSWYVGSNVPGKPRRVLSYVGGVGAYRDATLEAAAAGYKGFALS
What is the function of this protein?
Plays an important role in the metabolism of acetone derived from propane oxidation (PubMed:17071761).  Catalyzes the oxidation of acetone to methyl acetate (PubMed:17071761, PubMed:30392152).  Exhibits high catalytic efficiency towards various linear and cyclic ketones, such as butanone, 2-pentanone, 2-heptanone, 2-octanone, 2-nonanone, 2-decanone, cyclobutanone, cyclopentanone and cyclohexanone (PubMed:17071761, PubMed:30392152).  Elicits the highest catalytic efficiency towards butanone and cyclobutanone (PubMed:30392152).  Is highly specific for NADPH and cannot use NADH (PubMed:17071761, PubMed:30392152).
What are the official names of this protein?
Acetone monooxygenase (methyl acetate-forming), ACMO, NADPH-dependent acetone monooxygenase.
What is the protein family that this protein belongs to?
Belongs to the FAD-binding monooxygenase family.